TY  - JOUR
AB  - This systematic review and meta-analysis aimed to comprehensively assess the effects of attention-deficit/hyperactivity disorder (ADHD) and ADHD medications on the risk of depression and anxiety in children and adolescents. A comprehensive search of PubMed, Embase, Cochrane Library, and Web of Science was conducted up to January 30, 2024. The outcomes were depression and anxiety. Subgroup analysis was performed according to outcome population as youth onset, sex and duration of medication. Sensitivity analysis and publication bias assessment were also performed. Thirty-three studies were included. The children and adolescents with ADHD had a significantly higher risk of depressive disorder than those without ADHD [pooled relative risk (RR) = 2.27, 95% confidence interval (CI) = 1.57-3.29, P < 0.001]. The children and adolescents with ADHD were at a higher risk of major depressive disorder than those without ADHD (pooled RR = 2.20, 95%CI = 1.47-3.29, P = 0.002). The children and adolescents with ADHD had an increased risk of specific phobia versus those without ADHD (pooled RR = 1.68, 95%CI = 1.16-2.44, P = 0.006). The risk of social phobia in the ADHD group was higher than that in the non-ADHD group (pooled RR = 1.71, 95%CI = 1.13-2.61, P = 0.012). The children and adolescents with ADHD were at an elevated risk of agoraphobia compared with those without ADHD (pooled RR = 4.99, 95%CI = 1.51-16.56, P = 0.009). Children and adolescents with stimulant medications had a significantly lower risk of depression than those without stimulant medications (pooled RR = 0.80, 95%CI = 0.72-0.89, P < 0.001). In conclusion, children and adolescents with ADHD had higher risks of depressive disorder, major depressive disorder, specific phobia, social phobia, and agoraphobia than those without ADHD. Stimulant medications for ADHD were associated with a reduced risk for depression.
AN  - 39740618
AU  - Zhang,
AU  - Y.
AU  - Liao,
AU  - W.
AU  - Rao,
AU  - Y.
AU  - Gao,
AU  - W.
AU  - Yang,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.jpsychires.2024.12.022
L1  - internal-pdf://1729931074/508ed1ae-01e0-4f70-ad05-09ab1c842c8e.pdf
PY  - 2025
SP  - 623-639
T2  - Journal of Psychiatric Research
TI  - Effects of ADHD and ADHD medications on depression and anxiety in children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1016%2fj.jpsychires.2024.12.022
UR  - https://www.sciencedirect.com/science/article/pii/S0022395624007246?via%3Dihub
VL  - 181
ER  -
TY  - JOUR
AB  - **Objectives**: This comprehensive review and meta-analysis aimed to thoroughly identify the effectiveness of music therapy (MT) in improving behavioral symptoms in children with autism spectrum disorders (ASD) by analyzing the data from all relevant randomized controlled trials (RCTs) related to this field. **Methods**: From inception until September 18, 2024, PubMed, Web of Science, the Cochrane Library, SinoMed, and Embase were searched. Two reviewers extracted the data separately, and any controversies between the authors' assessments were resolved by conversation or speaking with another author. The behavioral symptoms scale score before and after the intervention was taken from the included trials and used to reflect the therapeutic effect of music therapy in children with autism. **Results**: 2607 records across all retrieved databases were discovered, thirteen of which were included in a meta-analysis with 1160 participants. According to the meta-analysis, children with autism showed a substantial improvement in their behavior symptoms when receiving music treatment (standardized mean difference [SMD] = -0.66, 95% confidence interval [CI]: -0.93 to -0.39, p < 0.001). With I-2 = 78% and P < 0.001, we did discover a medium level of heterogeneity among the included studies. **Conclusions**: MT has a positive impact on improving behavioral symptoms in children with autism. However, given the significant heterogeneity and limitations in this study, RCTs with rigorous methodological quality are still required to confirm the curative benefits of MT in autistic children precisely.
AN  - WOS:001411538500001
AU  - Gao,
AU  - X.
AU  - Y.
AU  - Xu,
AU  - G.
AU  - J.
AU  - Fu,
AU  - N.
AU  - N.
AU  - Ben,
AU  - Q.
AU  - Wang,
AU  - L.
AU  - Bu,
AU  - X.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.3389/fpsyt.2024.1511920
L1  - internal-pdf://4217501299/Gao-2025-The effectiveness of music therapy in.pdf
PY  - 2025
SP  - 11
T2  - Frontiers in Psychiatry
TI  - The effectiveness of music therapy in improving behavioral symptoms among children with autism spectrum disorders: a systematic review and meta-analysis
UR  - <Go to ISI>://WOS:001411538500001
UR  - https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1511920/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - **BACKGROUND**: We performed an umbrella review to synthesize evidence on the effects of physical activity (PA) interventions on indicators of physical and psychological health among children and adolescents, including body mass index (BMI), blood pressure (BP), depressive symptoms, and cognitive function. **METHODS**: PubMed, Embase, Web of Science, and the Cochrane Library were systematically searched from inception through 31 July 2023. We included meta-analyses of randomized controlled trials exploring the effects of PA interventions on BMI, BP, depressive symptoms, or cognitive function in healthy or general children and adolescents. Standard Mean Difference (SMD) was calculated for continuous outcome indicators, while Relative Risk (RR) was calculated for categorical outcome indicators. **RESULTS**: A total of 21 meta-analyses were included. The evidence for the effects of PA interventions on reducing BMI [n = 68,368, SMD = - 0.04, 95% confidence interval (CI) = - 0.07 to - 0.01, P = 0.012, I<sup>2</sup> = 46.6%], relieving diastolic BP (n = 8204, SMD = - 1.16, 95% CI = - 2.12 to - 0.20, P = 0.018, I<sup>2</sup> = 83.1%), preventing depressive symptoms (n = 5146, SMD = - 0.21, 95% CI = - 0.31 to - 0.12, P < 0.001, I<sup>2</sup> = 29.0%), and promoting cognitive function (n = 19,955, SMD = 0.40, 95% CI = 0.27-0.54, P < 0.001, I<sup>2</sup> = 88.0%) was all weak but significant (class IV evidence). Subgroup analyses demonstrated that school-based and after-school PA interventions, curricular PA interventions, and PA interventions emphasizing enjoyment were more effective in reducing BMI, while curricular PA and sports programs achieved greater executive function. **CONCLUSION**: PA interventions could weakly reduce BMI, relieve BP, prevent depressive symptoms, and promote cognitive function in general children and adolescents. Targeted interventions on PA should be a priority to promote physical and psychological health for children and adolescents, especially the curricular PA emphasizing enjoyment in the school settings.
AN  - 39847308
AU  - Cai,
AU  - S.
AU  - Wang,
AU  - H.
AU  - Zhang,
AU  - Y.
AU  - H.
AU  - Zhao,
AU  - T.
AU  - M.
AU  - Yuan,
AU  - X.
AU  - Deng,
AU  - H.
AU  - W.
AU  - Chen,
AU  - Y.
AU  - P.
AU  - Liu,
AU  - Y.
AU  - F.
AU  - Dang,
AU  - J.
AU  - J.
AU  - Shi,
AU  - D.
AU  - Chen,
AU  - Z.
AU  - Y.
AU  - Li,
AU  - J.
AU  - X.
AU  - Huang,
AU  - T.
AU  - Y.
AU  - Huang,
AU  - Y.
AU  - M.
AU  - Hu,
AU  - Y.
AU  - F.
AU  - Chen,
AU  - Y.
AU  - J.
AU  - He,
AU  - G.
AU  - Wang,
AU  - M.
AU  - Xu,
AU  - J.
AU  - Chen,
AU  - S.
AU  - Zou,
AU  - Z.
AU  - Y.
AU  - Song,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1007/s12519-024-00874-3
L1  - internal-pdf://0810870215/Cai-2025-Could physical activity promote indic.pdf
PY  - 2025
SP  - 23
T2  - World Journal of Pediatrics
TI  - Could physical activity promote indicators of physical and psychological health among children and adolescents? An umbrella review of meta-analyses of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs12519-024-00874-3
UR  - https://link.springer.com/article/10.1007/s12519-024-00874-3
UR  - https://link.springer.com/content/pdf/10.1007/s12519-024-00874-3.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Animal-assisted interventions (AAIs) have emerged as a promising nonpharmacological intervention option for children diagnosed with attention-deficit/hyperactivity disorder (ADHD). However, recent systematic reviews have been primarily narrative. Additionally, the pooled effectiveness of AAIs was absent from these systematic reviews. **METHODS**: We conducted a comprehensive systematic review and meta-analysis, searching multiple databases, including Web of Science, MEDLINE, CINAHL, Scopus, PsycINFO, EMBASE and Cochrane, from inception of the databases to March 2024. We retrieved 17 randomised controlled trials or quasi-experimental studies and used Review Manager 5.4.1 software to perform a meta-analysis of the effects of AAIs in treating children with ADHD. We conducted a set of random-effects meta-analyses to estimate standardised mean differences (SMD) with 95% confidence intervals (CI) using subgroup data by different outcome domains extracted from eight randomised controlled trials, in relation to changes in behavioural, mental and physical functioning in a total of 307 children with ADHD before and after the intervention. **RESULTS**: In comparison with non-AAI groups, AAIs significantly improved attention problems in children with ADHD (SMD = -0.42, 95% CI = -0.71 to -0.13), self-esteem (0.46, 0.14 to 0.78), learning and cognition problems (-0.69, -0.98 to -0.39) and motor proficiency (0.77, 0.11 to 1.42). The pooled effect of AAIs on the severity of ADHD symptoms in the experimental group was not significantly different from the effect of conventional treatments in the control group (0.10, -0.31 to 0.52). Similarly, AAIs had no significant positive effects on social interaction (-0.22, -0.51 to 0.06), social skills (-0.32, -0.87 to 0.24), problematic behaviours (-0.10, -0.54 to 0.35) or emotional problems, including depression and anxiety (-0.13, -0.51 to 0.24). **CONCLUSIONS**: As an ADHD management strategy complementary to gold-standard approaches, such as medication or multimodal interventions, AAIs did not appear to be more effective in improving the majority of core ADHD outcomes in children. Future studies should incorporate rigorous study designs with large sample sizes and a standard protocol to achieve more valid and reliable conclusion.
AN  - 39791320
AU  - Yu,
AU  - S.
AU  - Xue,
AU  - H.
AU  - Xie,
AU  - Y.
AU  - Shao,
AU  - G.
AU  - Hao,
AU  - Y.
AU  - Fan,
AU  - L.
AU  - Du,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1111/camh.12744
L1  - internal-pdf://4120813613/subito-le25020600523.pdf
PY  - 2025
SP  - 34-52
T2  - Child & Adolescent Mental Health
TI  - Review: Animal-assisted intervention for children with attention-deficit/hyperactivity disorder - a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1111%2fcamh.12744
UR  - https://acamh.onlinelibrary.wiley.com/doi/10.1111/camh.12744
VL  - 30
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Post-traumatic stress disorder (PTSD) is a potentially disabling condition that can lead to long-term impairments, with a significant proportion of adolescents being affected by trauma. Studies have suggested that trauma-focused cognitive behavioral therapy (TF-CBT) is an effective treatment for PTSD in adolescents, however, little is known about the relative advantages of different mind-body interventions. The network meta-analysis aims to evaluate and compare the efficacy of various mind-body interventions in alleviating PTSD symptoms in adolescents. **METHODS**: A systematic search was conducted across multiple databases including PubMed, Embase, Web of Science, Scopus, The Cochrane Library, CNKI, WFDSP, and VIP databases. Randomized controlled trials (RCTs) evaluating the effects of mind-body interventions on PTSD in adolescents were included. A network meta-analysis (NMA) was conducted to evaluate the effectiveness of various mind-body intervention therapies using the Surface Under the Cumulative Ranking curve (SUCRA). SUCRA calculates the mean of the cumulative percent area under the curve for each therapy, providing a comprehensive ranking of treatment efficacy. The primary outcomes measured were changes in PTSD symptom scores post-treatment and at follow-ups ranging from 1 to 12 months. **RESULTS**: A total of 20 studies involving 5 interventions and 2085 adolescents were included in the analysis. No inconsistencies were found between direct and indirect evidence. TF-CBT consistently demonstrated the most significant effect in reducing PTSD symptoms compared to routine care and no-treatment groups. The ranking of intervention efficacy from highest to lowest was as follows: TF-CBT (SUCRA = 87.3%), meditation, CBT, yoga combined with meditation and mindfulness (SUCRA = 32.3%). Due to limited evidence, the follow-up results for PTSD symptom changes remained inconclusive. **CONCLUSION**: Five mind-body interventions were found to be effective in treating PTSD symptoms in adolescents, with TF-CBT emerging as the most effective treatment. Findings suggest that yoga combined with meditation and mindfulness may have promising effects, however, further research is needed to confirm these results due to the limited evidence available.
AN  - 40001042
AU  - Bianjiang,
AU  - Z.
AU  - Jianchun,
AU  - Z.
AU  - Xiaoyu,
AU  - S.
AU  - Jian,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1186/s12888-025-06620-x
L1  - internal-pdf://0188541361/Bianjiang-2025-Mind-body intervention for post.pdf
PY  - 2025
SP  - 178
T2  - Bmc Psychiatry
TI  - Mind-body intervention for post-traumatic stress disorder in adolescents: a systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1186%2fs12888-025-06620-x
UR  - https://bmcpsychiatry.biomedcentral.com/counter/pdf/10.1186/s12888-025-06620-x.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: This systematic review aimed to 1) update the existing evidence on the antidepressant effects of aerobic exercise (AE) in youth. 2) Investigate any potential dose-response relationships between AE interventions and depressive symptom reduction. 3) Provide evidence-based insights to inform future research and clinical depression treatment. **METHODS**: Employing the PRISMA and PERSiST guidelines, a comprehensive search across nine databases (Web of Science, PubMed, Scopus, PsycINFO, SportDiscus, CINAHL, Medline, Embase, and CNKI) yielded a total of 782 relevant studies. Following rigorous selection criteria, 26 eligible studies (comprising 22 different samples) were included in the analysis, featuring a combined sample size of 1308 participants. The meta-analysis was conducted via R. **RESULTS**: AE notably decreased depressive symptoms among youth [g = -0.92; 95% CI (-1.16, -0.69); p < 0.01]. Significant dose-response relationships were observed across age groups [beta = -0.06; 95% CI (-0.12, 0.00), p < 0.05], the intensity [beta = -0.03; 95% CI (-0.06, 0.00); p < 0.05], and the duration ^ 2 [beta = 0.001, 95% CI (0.001, 0.002), p < 0.05] of the AE intervention. **CONCLUSIONS**: Aerobic exercise interventions can effectively alleviate depressive symptoms in youth. A moderate-intensity AE program, lasting 25-40 min and conducted three times a week for 9-15 weeks, can increase alleviation of depression.
AN  - 39800178
AU  - Yang,
AU  - Q.
AU  - Wang,
AU  - J.
AU  - Lu,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.psychsport.2025.102803
L1  - internal-pdf://3096286872/6c7c39fc-171f-4765-b2a1-f953d98c2960.pdf
PY  - 2025
SP  - 102803
T2  - Psychology of Sport & Exercise
TI  - The impact of aerobic exercise on depression in young people: A meta regression and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1016%2fj.psychsport.2025.102803
UR  - https://www.sciencedirect.com/science/article/pii/S1469029225000020?via%3Dihub
VL  - 77
ER  -
TY  - JOUR
AB  - **Background**: To evaluate the effect of virtual reality therapy on anxiety disorders in adolescents and adults by Meta-analysis. **Methods**: A comprehensive literature search was conducted by PubMed, Web of Science, Embase, CINAHL, Scopus, Cochrane (from inception to November 2024). Two researchers independently performed literature screening, quality evaluation and data extraction, and Stata16.0 and Review Man 5.4 software were used for Meta-analysis. **Results**: A total of 33 studies involving 3182 adolescents and adults with anxiety disorders were included. The results of Meta-analysis showed that compared with conventional interventions, virtual reality therapy significantly improved the symptoms and level of anxiety in patients with anxiety disorder [SMD = -0.95, 95%CI (-1.22,-0.69), Z = 7.05, P < 0.00001]. **Conclusion**: The current findings suggest that VR therapy interventions have a positive effect on improving the anxiety state of patients with anxiety disorders. The aforementioned research findings must be confirmed by more high-caliber studies due to the number and quality limitations of the contained literature. **Systematic review registration**: https://www.crd.york.ac.uk/prospero/display, identifier CRD42024574772.
AN  - 40084050
AU  - Zeng,
AU  - W.
AU  - Xu,
AU  - J.
AU  - Yu,
AU  - J.
AU  - Chu,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.3389/fpsyt.2025.1553290
L1  - internal-pdf://2447595628/Zeng-2025-Effectiveness of virtual reality the.pdf
PY  - 2025
SP  - 1553290
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Effectiveness of virtual reality therapy in the treatment of anxiety disorders in adolescents and adults: a systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.3389%2ffpsyt.2025.1553290
UR  - https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2025.1553290/pdf
VL  - 16
ER  -
TY  - JOUR
AB  - **Introduction**: Social impairments and repetitive behaviors are at the core symptoms of autism spectrum disorder (ASD). Intranasal administration of the neuropeptide oxytocin (OXT) is a promising treatment. However, there have been inconsistencies in the effects of OXT on social impairments and repetitive behaviors. **Methods**:  A comprehensive search in PubMed, the Cochrane Library, Embase, and Web of Science was conducted to gather randomized controlled trials (RCTs) on the efficacy of OXT in patients diagnosed with ASD up to 11/06/2024. The core outcomes were social impairments measured by total Social Responsiveness Scale (SRS) scores and repetitive behaviors measured by the Repetitive Behavior Scale (RBS). **Results**: This meta-analysis ultimately included 12 RCTs with 498 ASD patients. In an initial analysis, intranasal OXT showed no significant effect on social impairments. For a high dose of 48 IU per day, a beneficial effect on social impairments was found. According to the dose-response meta-analysis, the results indicated that higher doses of OXT might be more effective for social impairments. Depending on repetitive behaviors, the overall analysis showed no significant effect, while the dose over 48 IU per day revealed significant results and the dose-response meta-analysis suggested that higher doses could be more effective for repetitive behaviors. **Discussion**: Although these findings show no consistent beneficial effects, the results of the dose-response meta-analysis suggest that high doses of intranasal OXT per day may be more effective in ASD. Systematic review registration https://www.crd.york.ac.uk/prospero, identifier CRD42024567213.
AN  - WOS:001418819600001
AU  - Zhang,
AU  - Y.
AU  - Y.
AU  - Zhang,
AU  - X.
AU  - L.
AU  - Huang,
AU  - L.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.3389/fpsyt.2024.1477076
L1  - internal-pdf://0304085189/Zhang-2025-Optimal dose of oxytocin to improve.pdf
PY  - 2025
SP  - 11
T2  - Frontiers in Psychiatry
TI  - Optimal dose of oxytocin to improve social impairments and repetitive behaviors in autism spectrum disorders: meta-analysis and dose-response meta-analysis of randomized controlled trials
UR  - <Go to ISI>://WOS:001418819600001
UR  - https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1477076/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Early intervention may prevent maltreatment during infancy. This study examined the effectiveness of interventions initiated during the perinatal period to prevent child abuse and neglect. **METHODS**: We searched the MEDLINE, PsycINFO, Embase, and Cochrane Central Register of Controlled Trials databases for articles published before February 2023. Randomized controlled trials of interventions that began during pregnancy or within the first year postpartum, aimed at preventing child abuse and neglect in at-risk families, were included. The risk of bias in each study was evaluated using RoB 2. Outcomes from each study were combined using random-effects meta-analysis. The certainty of the evidence was assessed using the GRADE approach. **FINDINGS**: A total of 1746 articles were assessed for eligibility; 56 reports from international sources met the inclusion criteria, and 32 reports were included in the meta-analysis. Nineteen intervention studies based on 25 reports provided results regarding child maltreatment, and the overall risk ratio of the meta-analysis at the time of final reporting (evaluation period: 4-225 months) was 0.92 (95 % confidence interval [CI]: 0.79-1.07). In subgroup analysis by intervention type, the risk ratio for comprehensive support was 1.74 (95 % CI: 1.05-2.87). **INTERPRETATION**: Few studies have demonstrated the overall effectiveness of abuse prevention interventions for pregnant women with psychosocial risks. The timing and severity of child maltreatment reports must be considered, as they may reflect the effectiveness of early detection in preventing more serious future abuse.
AN  - 39731876
AU  - Tamon,
AU  - H.
AU  - Suto,
AU  - M.
AU  - Yoshitsugu,
AU  - H.
AU  - Maruyama,
AU  - N.
AU  - Ogawa,
AU  - K.
AU  - Takehara,
AU  - K.
AU  - Tachibana,
AU  - Y.
AU  - Kawashima,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.chiabu.2024.107154
L1  - internal-pdf://2389020063/02740bb3-b1e5-470b-b026-cdf7545eb3d7.pdf
PY  - 2025
SP  - 107154
T2  - Child Abuse & Neglect
TI  - Interventions for expectant and new parents designed to prevent child abuse and neglect in at-risk families: Systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1016%2fj.chiabu.2024.107154
UR  - https://www.sciencedirect.com/science/article/pii/S0145213424005441?via%3Dihub
VL  - 160
ER  -
TY  - JOUR
AB  - **Aims**: This study aimed to compare the efficacy of non-pharmacological interventions in children with preoperative anxiety. **Background**: It is estimated that preoperative anxiety affects up to 60% of children which is associated with both immediate and long-term adverse outcomes. Several non-pharmacological interventions have been demonstrated to be effective, but further research is necessary to determine which is the most effective.**Design**: This study was conducted and reported in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) 2020 checklist. **Methods**: We searched randomised controlled trials in twelve databases from which inception to March 31, 2024. The primary outcome was the severity of preoperative anxiety change from the baseline to the endpoint which is usually before the anaesthesia induction. Within the frequentist framework, a random-effects network meta-analysis (NMA) was used to compare the primary outcomes. The surface under the cumulative ranking curve (SUCRA) was used to rank each intervention separately. Subgroup and sensitivity analyses were carried out for the primary outcomes. **Results**: A total of 36 randomised controlled trials (RCTs) with 3182 paediatric patients were included. Based on the results, psychological + digital health intervention was significantly more effective than control groups and ranked highest. Combined parental presence during induction anaesthesia and video games (PPIA + VG) had significant benefits compared to almost all other interventions with the highest rank. **Conclusion**: Psychological + digital health interventions, especially PPIA + VG, may be the most effective non-pharmacological interventions for reducing preoperative anxiety in children. It is necessary to conduct more RCTs to evaluate the efficacy of different non-pharmacological interventions. **Relevance to Clinical Practice**: Non-pharmacological interventions can effectively improve preoperative anxiety in children. **Patient or Public Contribution**: No patient or public contribution applies to this work. **Trial Registration**: PROSPERO CRD42024509512 ()
AN  - WOS:001390493300001
AU  - Chen,
AU  - H.
AU  - T.
AU  - Zhang,
AU  - J.
AU  - H.
AU  - Li,
AU  - S.
AU  - A.
AU  - Zhang,
AU  - H.
AU  - Y.
AU  - Wei,
AU  - L.
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1111/jocn.17582
L1  - internal-pdf://1099492102/Chen-2025-Non-pharmacological Interventions fo.pdf
PY  - 2025
SP  - 15
T2  - Journal of Clinical Nursing
TI  - Non-pharmacological Interventions for Preoperative Anxiety in Children: A Systematic Review and Network Meta-Analysis
UR  - <Go to ISI>://WOS:001390493300001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jocn.17582?download=true
ER  -
TY  - JOUR
AB  - Substance use disorders (SUD) in mothers of young children can negatively impact the family unit and promote the intergenerational cycle of mental health disorders. This systematic review aims to: 1) provide an overview of substance use treatments for mothers of young children (from birth to 5 years old); 2) synthesize findings on maternal substance use and child/maternal mental health outcomes; and 3) identify key treatment components. Database searches in Medline, PsycINFO, PubMED, and PsycARTICLES were conducted on May 7th, 2024. A total of 14, 916 articles were identified following duplicate removal. Articles were screened following PRISMA guidelines. Eight articles (n = 900) met inclusion criteria. Outcomes of interest included maternal substance use, child/maternal mental health, and treatment components. All studies indicated maternal substance use treatments were at least as, or more, effective in improving maternal substance use and child/maternal mental health outcomes compared to controls. Treatment components included: mother/family mental health, basic needs, parenting skills, occupation/education, operant conditioning, crisis management, and medical education. Operant conditioning was the only treatment component which appeared to positively impact maternal substance use outcomes; no other treatment components were associated with outcomes of interest. This review provides preliminary evidence highlighting the benefits of substance use treatments for mothers of young children on substance use and mental health outcomes. Future randomized controlled trials with harmonized outcome measures and qualitative data that identifies treatment needs of mothers with lived experience are crucial to evaluate maternal substance use treatments and improve treatment development.
AN  - 39798357
AU  - Joyce,
AU  - K.
AU  - M.
AU  - Delaquis,
AU  - C.
AU  - P.
AU  - Alsaidi,
AU  - T.
AU  - Sulymka,
AU  - J.
AU  - Conway,
AU  - A.
AU  - Garcia,
AU  - J.
AU  - Paton,
AU  - A.
AU  - Kelly,
AU  - L.
AU  - E.
AU  - Roos,
AU  - L.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.addbeh.2024.108241
L1  - internal-pdf://0285803876/891969fa-f324-4788-943b-f67d14c60fb6.pdf
PY  - 2025
SP  - 108241
T2  - Addictive Behaviors
TI  - Treatment for substance use disorder in mothers of young children: A systematic review of maternal substance use and child mental health outcomes
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.addbeh.2024.108241
UR  - https://www.sciencedirect.com/science/article/pii/S0306460324002909?via%3Dihub
VL  - 163
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis aim to summarize and analyze current research on the effects of MI on neurodevelopment in children of all ages and health statuses to provide a reference for music therapy (MT) and its clinical research in pediatrics. We conducted a comprehensive search of PubMed, Embase, Web of Science, and Cochrane Library databases up to December 2023, focusing on randomized controlled trials that evaluated neurodevelopmental outcomes following MI. Our analysis, which included seven studies involving 337 participants, employed standardized mean difference (SMD) calculations to assess outcomes across multiple neurodevelopmental scales. While no significant cognitive improvements were observed on the Bayley-III scale, positive effects were noted in language, motor skills, and IQ scores when assessed via Gesell, CSBQ, and IQ scales. Our research underscores the potential of music intervention in the process of children's neurodevelopment, including cognitive function, language, motor and IQ. Based on the limitations, researchers should carefully design their MI protocols, ensuring standardization and avoiding probable confounding factors such as regional specificity, age ranges and special populations, it will contribute to more robust results and improve the comparability of findings across studies.
AN  - 40140669
AU  - Jiang,
AU  - D.
AU  - Liu,
AU  - X.
AU  - Lin,
AU  - Q.
AU  - Wang,
AU  - G.
AU  - Wang,
AU  - G.
AU  - Zhang,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1038/s41598-025-93795-8
L1  - internal-pdf://2092390570/Jiang-2025-Music intervention for neurodevelop.pdf
PY  - 2025
SP  - 10388
T2  - Scientific Reports
TI  - Music intervention for neurodevelopment in the pediatric population: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1038%2fs41598-025-93795-8
UR  - https://www.nature.com/articles/s41598-025-93795-8.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Anxiety disorders are among the most prevalent mental health conditions in childhood, affecting an estimated 10 % to 20 % of children. Cognitive Behavioral Therapy (CBT) is the most commonly employed treatment for these disorders. This study utilizes a meta-analytic approach to evaluate the effectiveness of CBT interventions in reducing anxiety levels among children diagnosed with anxiety disorders. **METHODS**: A comprehensive search was conducted in the "PubMed," "Science Direct," "Scopus," and "Web of Science" databases to identify randomized controlled and quasi-experimental studies that investigated the impact of CBT on children's anxiety levels. Studies that met the inclusion criteria were selected for analysis. The methodological quality of the selected studies was assessed using the "Critical Appraisal Checklists" developed by the Joanna Briggs Institute (JBI). Meta-analytic procedures were performed using the Review Manager 5.4.1 software. **RESULTS**: Twenty-nine studies published between 2015 and 2024 met the inclusion criteria and were included in the meta-analysis. The results indicate that CBT interventions are significantly effective in reducing anxiety levels in children with anxiety disorders (SMD: -1.51, 95 % CI: -2.07, -0.95, Z = 5.28, p < 0.00001). Among the various types of CBT, cognitive behavioral play therapy emerged as the most effective in reducing anxiety (SMD: -2.41, 95 % CI: -2.95, -1.88, Z = 8.84, p < 0.00001). Additionally, follow-up assessments at 3, 6, and 12 months post-intervention demonstrated that CBT has a sustained effect in lowering children's anxiety levels over time. **CONCLUSIONS**: This meta-analysis offers a valuable update to the existing literature by reinforcing the efficacy of CBT interventions in treating anxiety disorders in children.
AN  - 39779425
AU  - Alemdar,
AU  - H.
AU  - Karaca,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.pedn.2024.12.020
L1  - internal-pdf://3817986871/04f6324c-f1e0-4eb7-978a-db0ab176b746.pdf
PY  - 2025
SP  - 07
T2  - Journal of Pediatric Nursing
TI  - The effect of cognitive behavioral interventions applied to children with anxiety disorders on their anxiety level: A meta-analysis study
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.pedn.2024.12.020
UR  - https://www.sciencedirect.com/science/article/pii/S0882596324004652?via%3Dihub
VL  - 07
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: We conducted an umbrella review of systematic reviews (SRs), with or without meta-analysis (MA), of randomized controlled trials (RCTs) assessing nonpharmacological sleep interventions for children and adolescents across various clinical populations. **METHOD**: We searched multiple electronic databases up to January 24, 2024. Meta-analyzable data from RCTs in the retrieved SRs/MAs were pooled using Metaumbrella. Primary outcomes were subjective/objective child sleep parameters. Additional outcomes included child health/functioning and parental sleep/health. The quality of the MAs/SRs was assessed with Assessment of Multiple Systematic Reviews (AMSTAR-2), and the certainty of evidence using Grading of Recommendations, Assessment, Development and Evaluations (GRADE). **RESULTS**: We included 93 SRs/MAs covering 393 RCTs, with 25 (17%, 39%, and 30%: high, moderate, and low quality) providing data for quantitative synthesis. Behavioral interventions, usually multicomponent including parent training, psychoeducation, and/or specific sleep therapy/strategies, showed beneficial effects on night waking, sleep duration, overall sleep disturbance, mood/depression, and maternal sleep quality (standardized mean difference [SMD] = 0.10-0.80) in participants with sleep problems without a formal sleep disorder diagnosis. For those with a formal diagnosis (mainly insomnia), benefits were found for night waking, sleep efficiency (subjective/actigraphically measured), and sleep onset latency (mean SMD = 0.49-0.97). Those with attention-deficit/hyperactivity disorder (ADHD) improved in bedtime resistance, night waking, parasomnias, sleep anxiety, ADHD symptoms, sleep disturbance, and quality of life (mean SMD = 0.18-0.49). For those with autism, sleep disturbance improved (mean SMD = 0.70). However, all findings were of low to very low certainty of evidence. **CONCLUSION**: Among nonpharmacological interventions for sleep difficulties in youth, only behavioral interventions are supported by meta-analytic evidence, yet with small-to-moderate effect sizes and limited certainty of evidence. **PLAIN LANGUAGE SUMMARY**: This "umbrella review" (a review of reviews) analyzed 93 systematic reviews and meta-analyses of randomized controlled trials examining nonmedication sleep interventions for children and adolescents. The authors found that behavioral interventions, including parent training and psychoeducation, had positive effects on sleep issues like night waking, with effect sizes ranging from small to moderate. Improvements were also seen in children with ADHD and autism. However, the quality of the evidence for these benefits was rated as low to very low. This suggests that while behavioral approaches may help, more robust evidence is needed to confirm their benefits. **STUDY PREREGISTRATION INFORMATION**: The efficacy and tolerability of nonpharmacological interventions for sleep problems in children and adolescents: protocol for an umbrella review of systematic reviews and meta-analyses of randomised controlled trials. https://osf.io; j9qna/.
AN  - 39608635
AU  - Hornsey,
AU  - S.
AU  - J.
AU  - Gosling,
AU  - C.
AU  - J.
AU  - Jurek,
AU  - L.
AU  - Nourredine,
AU  - M.
AU  - Telesia,
AU  - L.
AU  - Solmi,
AU  - M.
AU  - Butt,
AU  - I.
AU  - Greenwell,
AU  - K.
AU  - Muller,
AU  - I.
AU  - Hill,
AU  - C.
AU  - M.
AU  - Cortese,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.jaac.2024.10.015
L1  - internal-pdf://3633993883/1-s2.0-S0890856724020215-main.pdf
PY  - 2025
SP  - 329-345
T2  - Journal of the American Academy of Child & Adolescent Psychiatry
TI  - Umbrella Review and Meta-Analysis: The Efficacy of Nonpharmacological Interventions for Sleep Disturbances in Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1016%2fj.jaac.2024.10.015
UR  - https://www.sciencedirect.com/science/article/pii/S0890856724020215?via%3Dihub
VL  - 64
ER  -
TY  - JOUR
AB  - Parent-focused interventions hold promise for reducing child anxiety, but their content varies greatly, and little is known on the intervention content. We estimated the effects of parent-focused interventions on child anxiety and the most effective combinations of theoretical components. We searched PsycINFO, Medline, and Web of Science in October 2022 for randomized trials on parent-focused interventions to reduce children's anxiety. We used robust variance estimation to estimate main effects and differential effects by individual theoretical components, and network meta-analysis to estimate the effects of clusters of components (preregistration: PROSPERO CRD42022362983). We identified 26 studies (k = 157, N = 4098). Parent-focused interventions had a significant medium effect on children's anxiety (d = -0.59; 95% CI [-0.92, -0.26]). Interventions used seven theoretically distinct components. No significant differential effects were found, but all clusters of components that produced significant effects contained a behavioral component. Adding cognitive and emotional components to behavioral components seemed beneficial. This meta-analysis highlights the potential of parent-focused interventions for children's anxiety, and of behavioral components in particular, but is limited by the very low certainty of evidence. More high-quality research is needed to understand the exact potential of parent-focused interventions on children's anxiety, and their most effective components.
AN  - 39847956
AU  - Rienks,
AU  - K.
AU  - Salemink,
AU  - E.
AU  - Laas
AU  - Sigurardottir,
AU  - L.
AU  - B.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Staaks,
AU  - J.
AU  - P.
AU  - C.
AU  - Leijten,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.brat.2025.104692
L1  - internal-pdf://1937587830/f42c6db3-07dd-4894-945a-c5eba3e7ecf3.pdf
PY  - 2025
SP  - 104692
T2  - Behaviour Research & Therapy
TI  - Supporting parents to reduce children's anxiety: A meta-analysis of interventions and their theoretical components
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1016%2fj.brat.2025.104692
UR  - https://www.sciencedirect.com/science/article/pii/S0005796725000142?via%3Dihub
VL  - 185
ER  -
TY  - JOUR
AB  - This systematic review provides an overview of the current literature on the effects of physical activity (PA) as an intervention to treat anxiety symptoms in adolescents and young adults. Three searches (March and May 2022; July 2024) focusing on RCTs using a PA intervention of at least moderate intensity were carried out in PubMed, PsycInfo, SportDiscus, and Google Scholar. Studies were screened, and risk of bias was assessed for all included studies. In total 2,521 studies were retrieved, and 14 RCTs were retained. Studies were compared based on several criteria, such as type of exercise, intensity, delivery mode, PA alone or as add-on treatment. Results suggest that PA is more effective compared to inactive control conditions. Intensity (moderate or high) or type of exercise (aerobic or resistance training) requirements for anxiolytic effects are less clear. Participants with elevated anxiety scores benefit more from PA interventions than those with low anxiety scores. We conclude that PA is a promising intervention to treat anxiety in adolescents and young adults. Heterogeneity between studies is high, and many present methodological shortcomings. Little is known about the underlying mechanisms responsible for anxiety-reducing effects. To advance research, more high-quality studies are needed to develop effective and personalized PA interventions. (PsycInfo Database Record (c) 2025 APA, all rights reserved)
AN  - 2025-81742-001
AU  - Aumer,
AU  - Thierry
AU  - Vogele,
AU  - Claus
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1027/2512-8442/a000168
L1  - internal-pdf://0892858394/Aurner_2025.pdf
PY  - 2025
SP  - No Pagination Specified
T2  - European Journal of Health Psychology
TI  - Anxiety reducing effects of physical activity in adolescents and young adults: Revisiting the evidence
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=psyc24&DO=10.1027%2f2512-8442%2fa000168
ER  -
TY  - JOUR
AB  - **Background/Objectives**: Attention-deficit/hyperactivity disorder (ADHD) currently lacks a universally accepted biomarker or diagnostic test, underscoring the need for objective and effective assessment methods. Transcranial magnetic stimulation (TMS) has emerged as a promising tool for both assessing cortical excitability and providing therapeutic interventions. This study conducted two independent meta-analyses to evaluate: 1) the potential of TMS in assessing cortical excitability, and 2) its therapeutic efficacy in managing ADHD symptoms. **Methods**: A systematic search was conducted in EMBASE, MEDLINE, PsycINFO, ClinicalTrials, and PubMed following PRISMA guidelines. The "cortical excitability" meta-analysis included studies comparing TMS-EMG or TMS-EEG neurophysiological measures between ADHD patients and healthy controls. The "therapeutic" meta-analysis focused on randomized controlled trials (RCTs) evaluating repetitive TMS (rTMS) effects on ADHD symptoms. Standardized mean differences (SMDs) were calculated for pooled effect sizes. **Results**: In the "cortical excitability" meta-analysis, 17 studies were included, demonstrating significantly reduced short-interval intracortical inhibition (SICI) in ADHD compared to healthy controls (pooled SMD = 0.65, 95% CI: 0.41-0.88, P < 0.00001). No significant differences were observed for motor evoked potentials (MEP), motor thresholds (aMT/rMT), cortical silent period (cSP), ipsilateral silent period (iSP), or intracortical facilitation (ICF). The "therapeutic" meta-analysis, encompassing 8 samples from 7 studies, demonstrated that rTMS significantly improved ADHD symptoms compared to control conditions (pooled SMD = 0.45, 95% CI: 0.19-0.70, P = 0.0006). **Conclusions**: This study highlights the potential of TMS as both a diagnostic and therapeutic tool in ADHD. Reduced SICI appears to be a key neurophysiological marker of ADHD, reflecting cortical GABAergic dysfunction. Additionally, rTMS shows promise in alleviating ADHD symptoms, though further studies are needed to confirm long-term therapeutic benefits and optimize stimulation protocols. **Systematic review registration**: https://www.crd.york.ac.uk/prospero/, identifier CRD42024507867.
AN  - WOS:001433515200001
AU  - Han,
AU  - Y.
AU  - Wei,
AU  - Z.
AU  - Y.
AU  - Zhao,
AU  - N.
AU  - Zhuang,
AU  - Q.
AU  - Zhang,
AU  - H.
AU  - Fang,
AU  - H.
AU  - L.
AU  - Zang,
AU  - Y.
AU  - F.
AU  - Feng,
AU  - Z.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - 10.3389/fpsyt.2025.1544816
L1  - internal-pdf://1121146988/Han-2025-Transcranial magnetic stimulation in.pdf
PY  - 2025
SP  - 17
T2  - Frontiers in Psychiatry
TI  - Transcranial magnetic stimulation in attention-deficit/hyperactivity disorder: a systematic review and meta-analysis of cortical excitability and therapeutic efficacy
UR  - <Go to ISI>://WOS:001433515200001
UR  - https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2025.1544816/pdf
VL  - 16
ER  -
TY  - JOUR
AB  - **Purpose**: Early language intervention is essential for children with indicators of language delay. Enhanced milieu teaching (EMT) is a naturalistic intervention that supports the language development of children with emerging language. We conducted a systematic review and meta-analysis of all qualifying single- case and group design studies that evaluate the experimental effects of EMT on child outcomes. **Method**: We evaluated the risk of bias in the included studies and conducted a descriptive analysis of study quality, effect sizes, and demographics. We reviewed a total of 29 single-case and 17 group design studies in which 1,590 children participated. **Results**: Out of 46 studies, 39 met the What Works Clearinghouse standards without reservations, showing low levels of risk of bias. The effects were comparable when EMT was implemented alone and when it was implemented with another intervention component, and EMT was more effective when implemented by caregivers than when implemented by therapists. Most studies did not report sufficient participant demographics. **Conclusions**: The EMT research literature published thus far is of high study quality; the effects across studies are comparable; and the intervention has been studied via a wide range of delivery modalities, contexts, implementers, and samples. Future research could systematically examine the effects of EMT and explore these varying intervention delivery, implementer, and learner characteristics as moderators.
AN  - WOS:001391132400018
AU  - Kang,
AU  - V.
AU  - Y.
AU  - Kim,
AU  - S.
AU  - Gregori,
AU  - E.
AU  - Maggin,
AU  - D.
AU  - M.
AU  - Chow,
AU  - J.
AU  - C.
AU  - Zhao,
AU  - H.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1044/2024_jslhr-24-00260
L1  - internal-pdf://0731908131/retrieve.cleaned.pdf
PY  - 2025
SP  - 259-281
T2  - Journal of Speech Language and Hearing Research
TI  - Systematic Review and Meta-Analysis of Enhanced Milieu Teaching
UR  - <Go to ISI>://WOS:001391132400018
VL  - 68
ER  -
TY  - JOUR
AB  - Adolescence is a vulnerable period for the onset of mental disorders and risk behaviours. Based on the Health-Promoting Schools Framework, whole-school interventions offer a promising strategy in this developmentally-sensitive cohort, through championing a systems-based approach to promotion and prevention that involves the key stakeholders in an adolescent's life. The evidence-base surrounding the effectiveness of whole-school interventions, however, remains inconclusive, partly due to the insufficient number of studies in previous meta-analyses. An updated systematic review and meta-analysis was thus conducted on the effectiveness of whole-school interventions promoting mental health and preventing risk behaviours in adolescence. From 12,897 search results, 28 studies reported in 58 publications were included. Study characteristics and implementation assessments were synthesized across studies, and quality appraisals and meta-analyses performed. Analyses identified a significant reduction in the odds of cyber-bullying by 25%, regular smoking by 31% and cyber-aggression by 37% in intervention participants compared to the control. Whole-school interventions thus offer substantial population health benefits through the reduction of these highly-prevalent issues affecting adolescents. The non-significant findings pertaining to the remaining eleven outcomes, including alcohol use, recreational drug use, anxiety, depression and positive mental health, are likely attributable to suboptimal translation of the Health-Promoting Schools Framework into practice and inadequate sensitivity to adolescents' local developmental needs. Given the ongoing challenges faced in the implementation and evaluation of these complex interventions, this study recommends that future evaluations assess the implementation of health-promoting activities in both intervention and control conditions and actively use this implementation data in the interpretation of evaluation findings.++Preregistration++: A pre-registered PROSPERO protocol (ID: CRD42023491619) informed this study.
AN  - 39869244
AU  - Lekamge,
AU  - R.
AU  - B.
AU  - Jain,
AU  - R.
AU  - Sheen,
AU  - J.
AU  - Solanki,
AU  - P.
AU  - Zhou,
AU  - Y.
AU  - Romero,
AU  - L.
AU  - Barry,
AU  - M.
AU  - M.
AU  - Chen,
AU  - L.
AU  - Karim,
AU  - M.
AU  - N.
AU  - Ilic,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1007/s10964-025-02135-6
L1  - internal-pdf://1905070114/Lekamge-2025-Systematic Review and Meta-analys.pdf
PY  - 2025
SP  - 27
T2  - Journal of Youth & Adolescence
TI  - Systematic Review and Meta-analysis of the Effectiveness of Whole-school Interventions Promoting Mental Health and Preventing Risk Behaviours in Adolescence
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs10964-025-02135-6
UR  - https://link.springer.com/content/pdf/10.1007/s10964-025-02135-6.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - **Background** Neonatal abstinence syndrome (NAS) is a drug withdrawal syndrome, mostly occurring after antenatal exposure to opioids. A neonate may be born physically dependent on opioid medications, which causes withdrawal symptoms (such as high pitched crying, disruptions in the sleep wake cycle and tremors) after birth. This is diagnosed with a standardised withdrawal assessment, such as the Finnegan score. Newborns developing NAS require medical treatment and longer hospital stays after birth than neonates without this condition. Treatments for NAS include multiple multimodal treatments to ease symptoms of withdrawal, such as swaddling, 'rooming in' and breastfeeding. If the standardised assessment exceeds a certain threshold, newborns are treated pharmacologically with an orally administered opioid. However, optimal NAS management continues to be debated. Acupuncture has been proposed as a potential intervention. Acupuncture involves stimulation of specific points on the body, either through the insertion of thin metal needles or with techniques that do not penetrate the skin, such as acupressure and laser. **Objectives** To assess if acupuncture (acupressure, needle, laser) reduces the treatment duration of neonatal abstinence syndrome (NAS) in newborn infants, reduces adverse events and reduces length of hospital stay. **Search methods** We used bibliographic databases (CENTRAL, PubMed, Embase) and trial registries, together with reference checking, citation searching and contact with study authors, to identify the studies that are included in the review. The latest search date was 25 August 2023. Selection criteria We included randomised controlled trials (RCTs) or quasi RCTs, and cluster randomised trials. We included infants born at full term and late preterm who were diagnosed with NAS within the first 72 hours after birth (i.e. showing significant signs as assessed using a standardised NAS assessment tool, e.g. presenting with withdrawal syndrome and Finnegan score > 8). We included studies where acupuncture (using invasive or non invasive techniques) was compared with: 1) no intervention; 2) placebo or sham treatment; 3) any pharmacological treatment; or 4) another type of acupuncture (e.g. penetration of the skin with a needle versus acupressure). Acupuncture could be given alone or in combination with conventional medical treatment for NAS ('standard care'), as long as the latter was administered to the control group as well. **Data collection and analysis** We used the standard methodological procedures expected by Cochrane. Our primary outcomes were duration of any pharmacological treatment for NAS, adverse events and length of hospital stay. We used GRADE to assess the certainty of evidence. **Main results** We included two single centre RCTs (104 infants). Both studies compared non invasive acupuncture added to standard care versus standard care. There were no studies where acupuncture was compared with placebo or sham treatment, pharmacological treatment or with another type of acupuncture. We did not identify any ongoing studies. One of the included studies was conducted with 28 babies in Austria, between 2009 and 2014; it was a prospective, blinded RCT of laser acupuncture, which was performed daily at ear and body acupuncture points, bilaterally, until morphine was discontinued. The other study was conducted with 76 babies in the USA between 1992 and 1996. It was a randomised, prospective, but unblinded study of acupressure: a small herbal seed was taped to an ear acupoint or acupoints, and the seed site was massaged for 30 to 60 seconds after each NAS scoring event. The evidence is very uncertain about the effect of adding acupuncture to standard care on the following outcomes. Duration of any pharmacological treatment for NAS. In one study, the median duration was 28 days (interquartile range (IQR) 22 to 33) and 39 days (IQR 32 to 48) in the acupuncture and control groups, respectively; in the other study, the mean duration of any pharmacological treatment for NAS was 22.1 days (standard deviation (SD) 16.6) and 22.7 days (SD 13.8) in the acupuncture and control groups, respectively (mean difference (MD) 0.60, 95% CI 7.45 to 6.25; 1 study, 76 infants). **Adverse events**. Both studies reported that no adverse effects occurred (risk difference (RD) 0.00 95% CI 0.05 to 0.05; 2 studies, 104 infants; I 2 = 0). Length of hospital stay in days. In one study (28 infants), the median and IQR were 35 (25 to 47) days and 50 (36 to 66) days in the acupuncture and control groups, respectively. In the other study (76 infants), the mean duration of any pharmacological treatment for NAS was 25.8 days (SD 16.4) and 26 days (SD 13.3) in the acupuncture and control groups, respectively (MD 0.20, 95% CI 6.90 to 6.50; 1 study, 76 infants). Highest score in a single standardised NAS assessment. One study (28 infants) reported median scores of 15 (IQR 13 to 18) and 16 (IQR 14 to 19) in the acupuncture and control groups, respectively; the other study (76 infants) reported that the average NAS score per scoring event was slightly lower (mean 4.95, SD 1.00) for the 'control' infants than for the infants assigned to acupuncture (mean 5.27, SD 1.04). We judged the certainty of the evidence to be very low for all these outcomes. No studies reported data on all cause mortality, pain or long term follow up. **Authors' conclusions** The limited available evidence is insufficient to establish the benefits and harms of acupuncture for the management of NAS in newborn infants. Both studies we included in this review assessed non invasive acupuncture and reported no adverse effects; however, data are drawn from a very small sample. In light of current limitations, clinicians are urged to approach the use of acupuncture in newborn infants with NAS cautiously, as there is currently no evidence to support its routine application. This systematic review highlights the need for well conducted, large randomised controlled trials to achieve an optimal information size to assess both the benefits and harms of acupuncture for NAS. In addition, comparisons of acupuncture techniques and sites should be made to assess effectiveness and feasibility. **Plain language summary** Acupuncture for babies with neonatal abstinence syndrome after exposure to drugs while in the womb **Key messages** Due to a lack of evidence, we are unable to draw any conclusions about the benefits and risks of acupuncture for babies with neonatal abstinence syndrome caused by being exposed to drugs while in the womb. Large studies that are well designed and reported are needed to find out more about the benefits and risks of acupuncture, including studies that make comparisons of acupuncture techniques, sites, timing and application. What is neonatal abstinence syndrome? Neonatal abstinence syndrome is a drug withdrawal syndrome, mostly occurring after being exposed to opoid drugs (such as heroin and methadone) while still in the womb. A neonate may be born physically dependent on a drug, which causes withdrawal symptoms after birth, for example, high pitched crying, a disrupted sleep wake cycle and tremors. Neonatal abstinence syndrome is diagnosed with a standardised withdrawal assessment, such as the Finnegan score. How is neonatal abstinence syndrome treated? Newborns developing neonatal abstinence syndrome require medical treatment and longer hospital stays after birth than neonates without this condition. Treatments for neonatal abstinence syndrome include multiple multimodal treatments to ease symptoms of withdrawal, such as swaddling, 'rooming in' and breastfeeding. If the standardised assessment exceeds a certain threshold, newborns are treated pharmacologically with an orally administered opioid. However, optimal neonatal abstinence syndrome management continues to be debated. Acupuncture has been proposed as a potential intervention. Acupuncture involves stimulation of specific points on the body, either through the insertion of thin metal needles ('invasive') or using techniques that do not penetrate the skin ('non invasive'), such as acupressure and laser. What did we want to find out? Our goal was to determine the benefits and risks of acupuncture in babies with neonatal abstinence syndrome (NAS). The primary outcomes were the duration of pharmacological treatment (medication), adverse events (harm) and length of hospital stay. What did we do? We searched for studies comparing acupuncture to no treatment, medications or other types of acupuncture (e.g. needle acupuncture versus laser acupuncture). Acupuncture could be given alone or in combination with conventional medical treatment for NAS ('standard care'), as long as the latter was administered to all participants in the study. **What did we find?** We found two studies including 104 infants in total. Both studies compared acupuncture (with techniques that do not penetrate the skin) added to standard care versus standard care. The two studies used different acupuncture techniques. One study of 28 infants, which was conducted in Austria between 2009 and 2014, used daily laser acupuncture on ear and body acupuncture points until the morphine used to treat the NAS symptoms in both groups was stopped. The other study, conducted in the USA between 1992 and 1996, included 76 babies and used acupressure with herbal seeds taped to ear acupoints that were massaged for 30 to 60 seconds, along with standard NAS care. **Main results** The evidence is very uncertain about the effects of adding acupuncture to standard care on how long infants need to take medication or stay in hospital. The evidence is also very uncertain about whether acupuncture can reduce the highest score an infant is given when a doctor assesses their neonatal abstinence syndrome. No adverse events were reported for any of the infants in either study, but as there were only 104 babies, it is not possible for us to draw any conclusions about the safety of acupuncture from these results. No studies provided information about pain or infant death. Nor did they follow up on the infants' progress in the longer term. **What are the limitations of the evidence?** The main limitation is that only two small studies were analysed. Some of the outcomes were not reported at all. Moreover, the studies could have been better designed. It is unclear whether there are studies on this topic that have been conducted but have not been published. As far as we are aware, there are no studies currently taking place. **How up to date is this evidence?** The evidence is up to date as of August 2023.
AN  - CD014160
AU  - Urlesberger,
AU  - B.
AU  - Cabano,
AU  - R.
AU  - Soll,
AU  - G.
AU  - Pahl,
AU  - A.
AU  - Oei,
AU  - J.
AU  - L.
AU  - Schmölzer,
AU  - G.
AU  - M.
AU  - Raith,
AU  - W.
AU  - Bruschettini,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - 10.1002/14651858.CD014160.pub2
KW  - *Acupuncture Therapy [methods]
KW  - *Neonatal Abstinence Syndrome [therapy]
KW  - *Randomized Controlled Trials as Topic
KW  - Acupressure [methods]
KW  - Analgesics, Opioid [adverse effects, therapeutic use]
KW  - Humans
KW  - Infant, Newborn
KW  - Laser Therapy [methods]
KW  - Length of Stay
N1  - [Central Editorial Service]
PY  - 2025
T2  - Cochrane Database of Systematic Reviews
TI  - Acupuncture for neonatal abstinence syndrome in newborn infants
UR  - https://doi.org//10.1002/14651858.CD014160.pub2
ER  -
TY  - JOUR
AB  - Adolescents are susceptible to developing depression and anxiety, and educational interventions could improve their mental well-being. This systematic review aimed to evaluate the effectiveness of universal educational prevention interventions in improving mental health literacy, depression, and anxiety among adolescents. Eight electronic databases were searched until June 2024: Cochrane Library, PubMed, EMBASE, CINAHL, PsycINFO, Scopus, Web of Science, ProQuest Dissertations, and Theses Global. Since the included studies assessed various aspects of mental health literacy, the results for mental health literacy were synthesized narratively. In contrast, a meta-analysis using a random-effects model was applied to the depression and anxiety outcomes. Heterogeneity was examined using I<sup>2</sup> statistics and Cochran's Q Chi-squared test. The Cochrane risk of bias tool and the GRADE approach conducted quality appraisal at the study and outcome levels, respectively. The review was reported according to the PRISMA guidelines. This review included 34 randomized controlled trials. Universal education prevention interventions were found to be promising in improving adolescents' mental health literacy but showed limited effects on individual mental health literacy components and on reducing depression (SMD = -0.06, 95%CI: [-0.11, -0.02], Z = 2.58, p = 0.01, I<sup>2</sup> = 45%) and anxiety (SMD = -0.00, 95%CI: [-0.06, 0.06], Z = 0.07, p = 0.94, I<sup>2</sup> = 58%) at post-intervention. Future trials should consider using a hybrid delivery model utilizing health care and the non-health care professionals. These interventions must incorporate skills-based sessions to develop emotional regulation strategies, complemented by extended follow-up periods that include booster sessions to reinforce learning. Given the very low quality of evidence as rated by the GRADE approach, current findings need to be interpreted with caution.
AN  - 39710627
AU  - Yani,
AU  - D.
AU  - I.
AU  - Chua,
AU  - J.
AU  - Y.
AU  - X.
AU  - Wong,
AU  - J.
AU  - C.
AU  - M.
AU  - Pikkarainen,
AU  - M.
AU  - Shorey,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1111/inm.13494
L1  - internal-pdf://4097350444/Yani_2025.pdf
PY  - 2025
SP  - e13494
T2  - International Journal of Mental Health Nursing
TI  - The Effects of Universal Educational Interventions in Improving Mental Health Literacy, Depression, and Anxiety Among Adolescents: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1111%2finm.13494
UR  - https://onlinelibrary.wiley.com/doi/10.1111/inm.13494
VL  - 34
ER  -
TY  - JOUR
AB  - **Background**: Children presenting to hospitals during the preoperative period are often exposed to procedures that cause significant stress. Through preoperative interventions, nurses play an important role in relieving the anxiety of children and their parents. **Objective**: This study was conducted to determine the effect of audio-visual methods on preoperative anxiety levels in children. **Methods**: PubMed (including MEDLINE), Cochrane, EBSCOHost, Web of Science, YOK National Thesis Center, and Google Scholar databases of randomized controlled studies published in the last 10 years were searched for this meta-analysis. 32 studies were included in the meta-analysis, and the total sample size was 2795. **Results**:  According to the results of the meta-analysis using the random-effects model, audio-visual methods had a positive effect on reducing anxiety (SMD: -1.312, %95 CI -1,666-(0,958), Z=-7,260, p < 0,001, Q-value = 556,572 I2 = 94.519). The moderator analysis demonstrated that cartoons (SMD:-1.645, p < 0.001), games (SMD:-1.931, p = 0.001), music (SMD:-0.534, p < 0.001), video showings (SMD:-1.363, p = 0.001), and virtual reality (SMD:-1.782, p < 0.001) reduced preoperative anxiety in children. **Conclusions**: Audio-visual methods are effective in reducing preoperative anxiety in children. The results of this study may provide pediatric perioperative nurses with additional information to help them decrease anxiety for patients and their families. (PsycInfo Database Record (c) 2025 APA, all rights reserved)
AN  - 2025-71044-001
AU  - Kulakac,
AU  - Nursen
AU  - Ustuner
AU  - Top,
AU  - Fadime
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1007/s10566-024-09849-x
L1  - internal-pdf://4087089781/Kulakac-2025-The effect of audio-visual method.pdf
PY  - 2025
SP  - No Pagination Specified
T2  - Child & Youth Care Forum
TI  - The effect of audio-visual methods on preoperative anxiety in children: A systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=psyc23&DO=10.1007%2fs10566-024-09849-x
UR  - https://link.springer.com/article/10.1007/s10566-024-09849-x
UR  - https://link.springer.com/content/pdf/10.1007/s10566-024-09849-x.pdf
ER  -
TY  - JOUR
AB  - **BACKGROUND AND AIM**: The use of acupuncture is becoming increasingly popular in the management of attention-deficit/hyperactivity disorder (ADHD). This systematic review consolidates evidence on acupuncture's efficacy and safety for treating ADHD in children and adolescents. **METHODS**: Controlled clinical trials assessing acupuncture against waitlist-control, placebo or active controls, or as an adjunct treatment were systematically searched across seven databases from inception to November 2024. Cochrane criteria were adhered to. **RESULTS**: We reviewed 25 studies with 1758 participants. None compared acupuncture to placebo or behavioral therapy. Subdomain analysis of the Conners' Parent Rating Scale indicated that acupuncture and Methylphenidate had comparable effects on Conduct Problems [SMD =0.03, 95%CI (-0.93, 0.99), p=0.95] and Learning Problems [SMD =0.29, 95%CI (-0.38, 0.97), p=0.39], but acupuncture was more effective in controlling Impulsive/Hyperactive symptoms [SMD =-1.71, 95%CI (-2.08, -1.35), p<0.01]. Insufficient sample size prevented confirmation of potential false positives. Acupuncture was safer and reduced Methylphenidate-related side-effects, including appetite loss, sleep disturbances, dry mouth, abdominal pain, and constipation. Acupuncture combined with behavioral therapy outperformed behavioral therapy alone in improving Psychosomatic symptoms [SMD =-0.88, 95%CI (-1.54, -0.23), p<0.01]. In the Integrated Visual and Auditory Continuous Performance Test, ADHD patients receiving acupuncture alongside conventional care performed better than those receiving conventional care alone. Nevertheless, the methodological quality of the included trials was very low to low, with significant bias risk, and 88% lacked follow-up. **CONCLUSIONS**: Acupuncture may offer an alternative for children and adolescents with ADHD who are intolerant to medication (primarily Methylphenidate). When combined with medication or behavioral therapy, it appeared more effective in ameliorating hyperactivity/impulsivity, inattention and conduct problems than standard treatments alone. It is also safe and well-tolerated. However, the supporting evidence is of low quality, and well-designed randomized controlled trials are needed. Thus, it is premature to recommend acupuncture as an alternative or adjunctive therapy for ADHD management.
AN  - 40086639
AU  - Zhao,
AU  - F.
AU  - Y.
AU  - Xu,
AU  - Y.
AU  - Kennedy,
AU  - G.
AU  - A.
AU  - Conduit,
AU  - R.
AU  - Zhang,
AU  - W.
AU  - J.
AU  - Jiang,
AU  - T.
AU  - Xu,
AU  - P.
AU  - Ho,
AU  - Y.
AU  - S.
AU  - Fu,
AU  - Q.
AU  - Q.
AU  - Chow,
AU  - C.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.ctim.2025.103163
L1  - internal-pdf://1374312493/1-s2.0-S096522992500038X-main.pdf
PY  - 2025
SP  - 103163
T2  - Complementary Therapies in Medicine
TI  - Is integrating acupuncture into the management of attention-deficit/hyperactivity disorder among children and adolescents now opportune and evidence-based? A systematic review with meta-analysis and trial sequential analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.ctim.2025.103163
UR  - https://www.sciencedirect.com/science/article/pii/S096522992500038X?via%3Dihub
VL  - 90
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Technology-based interventions are increasingly integrated to improve symptom management of pediatric oncology patients. However, evidence for their effectiveness remains low across various studies characterized by different methodologies and patient populations. This study aimed to synthesize and analyze the effectiveness of technology-based intervention in symptom management in pediatric oncology patients. **METHODS**: Six databases (PubMed, Web of Science, Cochrane Library, Ovid MEDLINE, CINAHL, and Scopus) were searched from January 1, 2014, to January 1, 2024. The methodological quality of the included studies was assessed using the Cochrane and JBI checklists. The PRISMA guidelines for systematic reporting were followed in this study. The search protocol has been registered with the PROSPERO International Prospective Register of Systematic Reviews (CRD42024516320). **RESULTS**: Thirteen studies with 624 pediatric oncology patients were analyzed. Significant differences were found between intervention and control groups in pain (Hedge's g=-0.695, 95% CI: -0.994 to -0.396, p < 0.001), fear (Hedge's g=-0.737, 95% CI: -1.01 to -0.464, p < 0.001), anxiety, and nausea and vomiting (Hedge's g=-0.573, 95% CI: -0.912 to -0.235, p < 0.001). **CONCLUSION**: The findings indicate that VR, iPad, humanoid robots, and Pain Squad reduce pain in pediatric oncology. VR, biofeedback-based VR, and iPads also alleviate fear, while all three plus humanoid robots mitigate anxiety. VR, interactive mobile apps, tablet games, text reminders, and iPads effectively decrease nausea and vomiting. More research is needed to evaluate the long-term effects of these interventions.
AN  - 39837686
AU  - Savas,
AU  - E.
AU  - H.
AU  - Akca
AU  - Sumengen,
AU  - A.
AU  - Semerci,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.soncn.2025.151808
L1  - internal-pdf://2758688889/4f1194b0-04f4-4193-9824-29774d2746b1.pdf
PY  - 2025
SP  - 151808
T2  - Seminars in Oncology Nursing
TI  - Effectiveness of Technology-Based Intervention in Symptom Management in Pediatric Oncology Patients: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.soncn.2025.151808
UR  - https://www.sciencedirect.com/science/article/pii/S0749208125000014?via%3Dihub
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Neonates admitted to the neonatal intensive care unit (NICU) undergo several painful procedures, causing significant stress. Maternal involvement in neonatal care significantly reduces pain and stress, thereby supporting better neurodevelopment in neonates. **CLINICAL QUESTION**: How do maternal involvement strategies reduce neonatal pain and pain-related stress in the NICU? **DATA SOURCES**: A systematic search was conducted on CENTRAL, PubMed Medline, EMBASE, CINAHL, Scopus, Web of Science, ProQuest databases, and Google Scholar for studies published between January 2007 and March 2024. **STUDY SELECTION**: A search across 7 databases yielded a total of 1360 studies, which were exported to Rayyan software for screening. Two independent authors conducted the screening based on the eligibility criteria. **DATA EXTRACTION**: Cochrane data collection forms were used to extract the data from the included studies. **RESULTS**: Out of 1360 titles identified during the initial search, a total of 27 randomized controlled trials were eligible and were included. Although there is a slight inconsistency in results, meta-analysis findings revealed that skin-to-skin care, holding, massage, feeding the baby, and maternal voice stimulation, significantly reduce procedural pain and pain-related stress, in neonates admitted to the NICU. **IMPLICATIONS FOR PRACTICE AND RESEARCH**: Given the consistent results, this systematic review strongly supports NICU healthcare professionals in encouraging mothers to engage in neonatal care activities to reduce procedural pain and related stress. More research is needed, including navigating the mothers on the importance of their involvement in neonatal care throughout the NICU admission and after hospital discharge.
AN  - 40048649
AU  - Siva,
AU  - N.
AU  - Praharaj,
AU  - M.
AU  - Tanay,
AU  - K.
AU  - Das,
AU  - S.
AU  - Nayak,
AU  - B.
AU  - S.
AU  - Lewis,
AU  - L.
AU  - E.
AU  - S.
AU  - Noronha,
AU  - J.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1097/ANC.0000000000001247
L1  - internal-pdf://0380655599/evidenced_based_recommendation_for_involving.3.pdf
PY  - 2025
SP  - 103-112
T2  - Advances in Neonatal Care
TI  - Evidenced-Based Recommendation for Involving Mothers to Reduce the Procedural Pain and Stress in High-Risk Neonates: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1097%2fANC.0000000000001247
VL  - 25
ER  -
TY  - JOUR
AB  - **Purpose**: This study aimed to evaluate the effectiveness of vigorous physical activity as an intervention for alleviating depressive symptoms among adolescents and young adults. **Methods**: A comprehensive search on systematically reliable databases was carried out, and studies running till August 2023 were considered in this study. The articles included in this meta-analysis assessed the impact of exercise interventions on depressive symptomatology in adolescents and young adults. Two independent investigators screened the studies, extracted data, and evaluated quality. **Results**: Physical activity produced an important reduction in depressive symptoms [SMD] = -4.23, 95% CI: -7.02, -1.44, p = 0.0001; a moderate effect size in both the adolescent population with clinical depression and adolescents who presented with subclinical depressive symptoms. Notably, vigorous physical exercise worked most favorably for adolescent depressive symptomatology, while moderate-intensity exercise was the best choice for adolescents with diagnosed clinical depression. **Conclusion**: This meta-analysis suggests that vigorous physical activity could reduce depressive symptoms in adolescents and young adults. However, further studies are needed to provide clearer recommendations regarding the type, duration, and intensity of exercise necessary to treat clinical depression in this population.
AN  - 40041423
AU  - Yang,
AU  - W.
AU  - Chen,
AU  - H.
AU  - Liu,
AU  - W.
AU  - Qu,
AU  - S.
AU  - Ge,
AU  - Y.
AU  - Song,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.3389/fnbeh.2025.1479326
L1  - internal-pdf://2285656141/Yang-2025-Efficacy of vigorous physical activi.pdf
PY  - 2025
SP  - 1479326
T2  - Frontiers in Behavioral Neuroscience
TI  - Efficacy of vigorous physical activity as an intervention for mitigating depressive symptoms in adolescents and young adults: a comprehensive systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.3389%2ffnbeh.2025.1479326
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11876554/pdf/fnbeh-19-1479326.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: To evaluate systematic reviews of randomised controlled trials (RCTs) on the effects of exercise on general cognition, memory and executive function across all populations and ages. **METHODS**: Systematic reviews and meta-analyses of RCTs evaluating the effects of exercise on general cognition, memory and executive function were eligible. Data extraction and risk of bias scoring were conducted in duplicate. The A MeaSurement Tool to Assess systematic Reviews (AMSTAR-2) was used to assess the risk of bias. Effect sizes were pooled using random effects models and reported as standardised mean differences (SMD). Subgroup analyses were conducted for participant and intervention characteristics. General cognition, memory and executive function. **DATA SOURCES**: CINAHL, The Cochrane Library, Embase, MEDLINE via OVID, Emcare, ProQuest Central, ProQuest Nursing and Allied Health Source, PsycINFO, Scopus, Sport Discus and Web of Science. **RESULTS**: 133 systematic reviews (2,724 RCTs and 258 279 participants) were included. Exercise significantly improved general cognition (SMD=0.42), memory (SMD=0.26) and executive function (SMD=0.24). Memory and executive function improvements from exercise were greater for children and adolescents than for adults and older adults. Those with attention-deficit/hyperactivity disorder exhibited greater improvement in executive function than other populations. Effects were generally larger for low- and moderate-intensity interventions. Shorter interventions (1-3 months) and exergames (video games that require physical movement) had the largest effects on general cognition and memory. Findings remained statistically significant after excluding reviews rated as low and critically low quality. **CONCLUSIONS**: These findings provide strong evidence that exercise, even light intensity, benefits general cognition, memory and executive function across all populations, reinforcing exercise as an essential, inclusive recommendation for optimising cognitive health. **TRIAL REGISTRATION NUMBER**: PROSPERO ID: CRD42023468991.
AN  - 40049759
AU  - Singh,
AU  - B.
AU  - Bennett,
AU  - H.
AU  - Miatke,
AU  - A.
AU  - Dumuid,
AU  - D.
AU  - Curtis,
AU  - R.
AU  - Ferguson,
AU  - T.
AU  - Brinsley,
AU  - J.
AU  - Szeto,
AU  - K.
AU  - Petersen,
AU  - J.
AU  - M.
AU  - Gough,
AU  - C.
AU  - Eglitis,
AU  - E.
AU  - Simpson,
AU  - C.
AU  - E.
AU  - Ekegren,
AU  - C.
AU  - L.
AU  - Smith,
AU  - A.
AU  - E.
AU  - Erickson,
AU  - K.
AU  - I.
AU  - Maher,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1136/bjsports-2024-108589
L1  - internal-pdf://2986629150/bjsports-2024-108589.full.pdf
PY  - 2025
SP  - 06
T2  - British Journal of Sports Medicine
TI  - Effectiveness of exercise for improving cognition, memory and executive function: a systematic umbrella review and meta-meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1136%2fbjsports-2024-108589
VL  - 06
ER  -
TY  - JOUR
AB  - **BACKGROUND**: This review aimed to synthesise the literature about interventions for parents of adolescents with intellectual disability, including parental experience of receiving interventions and intervention effectiveness. **METHODS**: Eligible interventions aimed to improve parenting skills and/or parent-adolescent relationships, adolescent behavioural/emotional problems and/or parent well-being. ASSIA, EMBASE, Medline, PsycINFO and Web of Science were last searched on 11 July 2024. The TIDieR checklist and the MMAT were used for quality appraisal. A narrative synthesis was conducted. (Pre-registration: PROSPERO CRD42022384409). **RESULTS**: Twelve studies with 1041 families were included. Intervention descriptions were detailed; however, study quality was mixed. Nearly all studies reported the intervention was associated with positive effects on parenting, parent-adolescent relationships, adolescent behaviour/emotional problems or parent well-being. Three randomised controlled trials (RCTs) offer the strongest evidence but are limited in quality. All studies investigating parent experiences reported positive responses. **CONCLUSIONS**: High-quality studies (e.g., RCTs) are needed to enable conclusions about efficacy and effectiveness.
AN  - 39967490
AU  - Scripps,
AU  - E.
AU  - Sutherland,
AU  - D.
AU  - Langdon,
AU  - P.
AU  - E.
AU  - Hastings,
AU  - R.
AU  - P.
AU  - Gray,
AU  - K.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1111/jar.70004
L1  - internal-pdf://0641272127/Scripps-2025-Supporting Parents of Adolescents.pdf
PY  - 2025
SP  - e70004
T2  - Journal of Applied Research in Intellectual Disabilities
TI  - Supporting Parents of Adolescents With Intellectual Disabilities: A Systematic Review of Interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1111%2fjar.70004
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jar.70004?download=true
VL  - 38
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: While numerous reviews examine digital interventions, including computer game-based, evidence regarding their effectiveness for ADHD symptoms remains mixed. Focusing on computer game-based interventions, this study aims to identify specific intervention features and trial-related factors that influence outcomes in pediatric ADHD symptoms through a systematic review and meta-analysis of randomized controlled trials. **METHODS**: Comprehensive literature searches were conducted in Web of Science, PubMed and PsycINFO. The certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. **RESULTS**: Seventeen studies were included. Beyond common game characteristics, some interventions incorporated additional elements-such as neurofeedback, physical exercise via virtual reality (VR) and social components-allowing subgroup analyses. The neurofeedback subgroup showed the largest effect size (standardized mean difference (SMD)=-0.51, 95 % confidence interval (CI) [-0.88, -0.15], heterogeneity index (I<sup>2</sup>)=45.85 %, p < 0.05, very low certainty of evidence), followed by the physical exercise/VR subgroup (SMD=-0.40, 95 %CI [-0.76, -0.04], I<sup>2</sup>=0.00 %, p < 0.05, very low certainty of evidence). Other subgroups, including those with social components or without additional elements, did not show significant effect sizes. The physical exercise/VR subgroup demonstrated small-to-medium effect sizes in both inattention and hyperactivity/impulsivity subscales, whereas the neurofeedback subgroup showed similar effects only in inattention. Trial-level factors, including participant demographics and intervention duration, showed no significant relationship with SMD in meta-regression. **CONCLUSION**: Although inconclusive, synergizing with game dynamics, neurofeedback and physical exercise/VR may enhance effectiveness of computer game-based interventions in addressing pediatric ADHD symptoms. Particularly, interventions with physical exercise/VR have potential to address both inattention and hyperactivity/impulsivity.
AN  - 40153883
AU  - Hamada,
AU  - T.
AU  - Seki,
AU  - M.
AU  - Nango,
AU  - E.
AU  - Shibata,
AU  - T.
AU  - Imai,
AU  - S.
AU  - Miyata,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.psychres.2025.116447
L1  - internal-pdf://1740527786/1-s2.0-S0165178125000964-main.pdf
PY  - 2025
SP  - 116447
T2  - Psychiatry Research
TI  - Enhancing effects of exercise and neurofeedback: A systematic review and meta-analysis of computer game-based interventions for pediatric ADHD
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.psychres.2025.116447
UR  - https://www.sciencedirect.com/science/article/pii/S0165178125000964?via%3Dihub
VL  - 348
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: In this systematic review and meta-analysis, we assessed and summarised the certainty of the evidence about the effects of gender affirming hormone therapy (GAHT) in individuals with gender dysphoria (GD). **METHODS**: We searched Medline, Embase, PsychINFO, Social Sciences Abstracts, LGBTQ+ Source and Sociological Abstracts from inception to September 2023. We included studies comparing GAHT with no GAHT in individuals aged <26 years with GD. Outcomes of interest included psychological and physical effects. Pairs of reviewers independently screened articles, abstracted data and assessed the risk of bias in the included studies. We performed meta-analyses and assessed the certainty of the evidence using the grading of recommendations assessment, development and evaluation (GRADE) approach. **RESULTS**: We included 24 studies. Comparative observational studies (n=9) provided mostly very low certainty evidence regarding GD, global function and depression. One comparative observational study reported that the odds of depression may be lower (OR 0.73 (95% CI 0.61 to 0.88), n (number of studies)=1, low certainty) in individuals who received GAHT compared with those who did not. Before-after studies (n=13) provided very low certainty evidence about GD, global function, depression and bone mineral density. Case series studies (n=2) provided high certainty evidence that the proportion of individuals with cardiovascular events 7-109 months after receiving GAHT was 0.04 (95% CI 0.03 to 0.05, n=1, high certainty).**CONCLUSION**: There is considerable uncertainty about the effects of GAHT and we cannot exclude the possibility of benefit or harm. Methodologically rigorous prospective studies are needed to produce higher certainty evidence. **TRIAL REGISTRATION NUMBER**: PROSPERO CRD42023452171.
AN  - 39855725
AU  - Miroshnychenko,
AU  - A.
AU  - Ibrahim,
AU  - S.
AU  - Roldan,
AU  - Y.
AU  - Kulatunga-Moruzi,
AU  - C.
AU  - Montante,
AU  - S.
AU  - Couban,
AU  - R.
AU  - Guyatt,
AU  - G.
AU  - Brignardello-Petersen,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1136/archdischild-2024-327921
L1  - internal-pdf://0294249320/Miroshnychenko-2025-Gender affirming hormone t.pdf
PY  - 2025
SP  - 12
T2  - Archives of Disease in Childhood
TI  - Gender affirming hormone therapy for individuals with gender dysphoria aged <26 years: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1136%2farchdischild-2024-327921
UR  - https://adc.bmj.com/content/archdischild/early/2025/02/11/archdischild-2024-327921.full.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - Autism spectrum disorder (ASD) has become an increasingly prominent global health issue. Sulforaphane is a phytochemical with multiple functions that target many of the same biochemical and molecular pathways (biomarkers) associated with ASD. This study aimed to conduct a meta-analysis based on sulforaphane's effect on Aberrant Behavior Checklist (ABC) and Social Responsiveness Scale (SRS) in patients with ASD. We conducted comprehensive searches in the PubMed, Medline, Cochrane, EMBASE, and Web of Science databases from their inception. The modified Cochrane risk of bias tool was used to check the risk of bias of the included studies. Review Manager 5.3 software was used to conduct this meta-analysis. The results of this meta-analysis showed that sulforaphane significantly improved irritability and hyperactivity symptoms, suggesting that sulforaphane has the potential for the combined treatment of autism. Additional studies are needed to confirm and explore the effect of sulforaphane.
AN  - 39951914
AU  - Guo,
AU  - J.
AU  - Wang,
AU  - Y.
AU  - He,
AU  - W.
AU  - Lou,
AU  - M.
AU  - Peng,
AU  - Y.
AU  - Shi,
AU  - H.
AU  - Lian,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.braindev.2025.104321
L1  - internal-pdf://2681493518/1-s2.0-S0387760425000026-main.pdf
PY  - 2025
SP  - 104321
T2  - Brain & Development
TI  - Effects of sulforaphane on ABC and SRS scales in patients with autism spectrum disorder: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1016%2fj.braindev.2025.104321
UR  - https://www.sciencedirect.com/science/article/pii/S0387760425000026?via%3Dihub
VL  - 47
ER  -
TY  - JOUR
AB  - We investigated the effect of cognitive training of executive functions on children's cognitive outcomes. To address this issue, a systematic meta-analysis of published research articles on cognitive training interventions was performed considering children's age, training duration, -procedure, and -technology in moderator analyses. The results (N = 57) of a random-effects-model showed that cognitive training was effective with a total effect size of g = 23 The training was more effective for younger compared to older children. Training benefits were found for near- and far-transfer tasks. The largest gains for a near-transfer skill were found for working memory. Both numeracy and literacy skills profited from training. Computer training was very effective, however, only a few studies used mobile technology. Non-adaptive training was associated with greater effect sizes and both group and individual training were similarly effective. Verbal feedback was important for younger children. School was an effective context for training, however, only a few studies were conducted at home or at the lab. The findings are discussed and advocate an early start of cognitive training interventions.
AN  - WOS:001396547000001
AU  - Birtwistle,
AU  - E.
AU  - Chernikova,
AU  - O.
AU  - Wünsch,
AU  - M.
AU  - Niklas,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1177/21582440241311060
L1  - internal-pdf://3896631946/f073ffd8-cfc8-4548-959e-4f590ee6022d.pdf
PY  - 2025
SP  - 18
T2  - Sage Open
TI  - Training of Executive Functions in Children: A meta-analysis of cognitive training interventions
UR  - <Go to ISI>://WOS:001396547000001
VL  - 15
ER  -
TY  - JOUR
AB  - Given the significance of gut microbiota in autism spectrum disorder (ASD), we aimed to assess the quality of systematic reviews (SRs) of studies assessing gut microbiota and effects of probiotic supplementation in children with ASD. PubMed, EMBASE, PsycINFO, Medline, and Cochrane databases were searched from inception to November 2024. We included SRs of randomised or non-randomized studies reporting on gut microbiota or effects of probiotics in children with ASD. A total of 48 SRs (probiotics: 21, gut microbiota: 27) were included. The median (IQR) number of studies and participants was 7 (5) and 328 (362), respectively, for SRs of probiotic intervention studies and 18 (18) and 1083 (1201), respectively, for SRs of gut microbiota studies in children with ASD. The quality of included SRs was low (probiotics: 12, gut microbiota: 14) to critically low (probiotics: 9, gut microbiota: 13) due to lack of reporting of critical items including prior registration, deviation from protocol, and risk of bias assessment of included studies. Assuring robust methodology and reporting of future studies is important for generating robust evidence in this field.
AN  - 40142438
AU  - Agrawal,
AU  - S.
AU  - Rath,
AU  - C.
AU  - Rao,
AU  - S.
AU  - Whitehouse,
AU  - A.
AU  - Patole,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.3390/microorganisms13030545
L1  - internal-pdf://3227080859/Agrawal_2025.pdf
PY  - 2025
SP  - 27
T2  - Microorganisms
TI  - Critical Appraisal of Systematic Reviews Assessing Gut Microbiota and Effect of Probiotic Supplementation in Children with ASD-An Umbrella Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.3390%2fmicroorganisms13030545
VL  - 13
ER  -
TY  - JOUR
AB  - **OBJECTIVES**: To assess the effectiveness of digital health on symptoms and health-related quality of life in children and adolescent cancer survivors. **METHODS**: We searched PubMed, Embase, Web of Science, Cochrane Library, and CINAHL databases on July 11, 2024, to identify randomized controlled trials of the impact of digital health on children and adolescent cancer survivors aged 0-19 years. The Cochrane Risk of Bias Tool version 1.0 was used to evaluate the quality of randomized controlled trials. It was registered in PROSPERO with the number CRD42024526347. **RESULTS**: A total of 23 randomized controlled trials were included, of which 18 were meta-analyzed. Compared with usual care, digital health interventions can significantly improve pain (SMD = -0.86, 95% CI: -1.21 to -0.51, P < 0.001), nausea and vomiting (SMD = -0.49, 95% CI: -0.97 to -0.02, P = 0.04), anxiety (SMD = -1.05, 95% CI: -1.60 to -0.50, P = 0.0002), distress (SMD = -0.74, 95% CI: -1.07 to -0.41, P < 0.001), fear (MD = -0.91, 95% CI: -1.40 to -0.42, P = 0.0003), and health-related quality of life (SMD = 1.41, 95% CI: 1.11 to 1.70, P < 0.001) in children and adolescent cancer survivors. However, improvements in fatigue and anger were not significant. **CONCLUSIONS**: Our systematic review provides evidence that digital health interventions have great potential to improve the symptoms and health-related quality of life of children and adolescent cancer survivors. **IMPLICATIONS FOR CANCER SURVIVORS**: Digital technologies to improve symptoms and health-related quality of life in children and adolescent cancer survivors deserve wider application.
AN  - 40146477
AU  - Zhao,
AU  - B.
AU  - Zhang,
AU  - T.
AU  - Chen,
AU  - Y.
AU  - Zhang,
AU  - S.
AU  - Bao,
AU  - L.
AU  - Zhang,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1007/s11764-025-01788-3
L1  - internal-pdf://2040617115/Zhao-2025-Effects of digital health on symptom.pdf
PY  - 2025
SP  - 27
T2  - Journal of Cancer Survivorship
TI  - Effects of digital health on symptoms and health-related quality of life in children and adolescent cancer survivors: a meta-analysis and systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs11764-025-01788-3
UR  - https://link.springer.com/article/10.1007/s11764-025-01788-3
UR  - https://link.springer.com/content/pdf/10.1007/s11764-025-01788-3.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - **BACKGROUND**: The mental health chatbot is dedicated to providing assistance to individuals grappling with the complexities of depression and anxiety. **OBJECTIVE**: The study aimed to evaluate the effectiveness of the mental health chatbot in alleviating symptoms of depression and anxiety among adolescents and young adults. **METHODS**: A systematic review framework was employed with a protocol pre-registered on Prospero (CRD42023418877). Databases were systematically searched, including PubMed, ACM Digital Library, Embase, Cochrane and IEEE. Data synthesis was conducted narratively, and meta-analysis was performed by pooling data from the original studies. **RESULTS**: Ten randomized controlled trials focused on an acute population, mainly females and university students. Chatbots designed for daily conversations and mood monitoring, using cognitive behavioral therapy techniques, showed efficacy in treating depression (95% CI = -1.09 to -0.23; p = .003). However, it is essential to highlight that these interventions utilizing chatbots for mental health were not found to be efficacious in managing symptoms of anxiety (95% CI = -0.56 to 0.4; p = .74). **CONCLUSIONS**: Evidence supports the effectiveness of mental health chatbots in treating depression, but further exploration and refinement are needed to optimize their efficacy in managing anxiety.
AN  - 39935147
AU  - Chen,
AU  - T.
AU  - H.
AU  - Chu,
AU  - G.
AU  - Pan,
AU  - R.
AU  - H.
AU  - Ma,
AU  - W.
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1080/17434440.2025.2466742
L1  - internal-pdf://0018805418/Effectiveness of mental health chatbots in dep.pdf
PY  - 2025
SP  - 1-9
T2  - Expert Review of Medical Devices
TI  - Effectiveness of mental health chatbots in depression and anxiety for adolescents and young adults: a meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1080%2f17434440.2025.2466742
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Movement behaviors, including physical activity (PA), sedentary behavior (SB), and sleep, are fundamental to early childhood development. These behaviors interact dynamically within a 24-hour period, creating a complex balance that influences not only physical health but also cognitive and emotional well-being in young children. While the physical health benefits of movement behaviors are well-documented, systematic evaluations of how interventions targeting these behaviors affect cognitive development in preschool-aged children remain limited. **METHODS**: This review was guided through PRISMA 2020 guidelines. We conducted a systematic review of randomized controlled trials (RCTs) to evaluate the impact of interventions targeting PA, SB, and sleep on cognitive outcomes in preschool-aged children. A comprehensive search was performed across five databases: PubMed, PsycInfo, Web of Science, Embase, and CINAHL, covering studies published between January 2000 and December 2023. Eligible studies were those that focused on at least one movement behavior, had a minimum intervention duration of four weeks, and assessed cognitive development as a primary outcome. The cognitive outcomes evaluated included executive function, attention, memory, and other key domains critical to early childhood development, such as language, processing speed, and social cognition. **RESULTS**: Twenty-two RCTs (14 individual, 8 cluster) met the inclusion criteria. Of these, 21 studies focused on PA, while only one targeted SB, and none specifically addressed sleep or combined movement behaviors. PA interventions, particularly those involving cognitively engaging activities, significantly improved cognitive domains such as executive function, inhibition, and attention, with effect sizes ranging from moderate to large (Cohen's d > 0.5). The SB-focused study did not report significant cognitive improvements. A clear gap exists in understanding the effects of sleep and multi-behavior interventions on cognitive outcomes. **CONCLUSIONS**: Cognitively engaging PA interventions demonstrated the largest effects, while motor skill-focused and general PA programs produced moderate to smaller gains. Evidence on SB and sleep interventions remains limited, with no studies exploring the combined effects of these three movement behaviors. Future research should focus on integrated interventions that address PA, SB, and sleep to achieve a more comprehensive understanding of their collective impact on cognitive development in early childhood. **TRIAL REGISTRATION**: This study was registered with PROSPERO under the registration number CRD42023479156.
AN  - 39849503
AU  - Pacheco,
AU  - C.
AU  - Culkin,
AU  - V.
AU  - Putkaradze,
AU  - A.
AU  - Zeng,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1186/s12966-025-01705-y
L1  - internal-pdf://2288464761/Pacheco-2025-Effects of movement behaviors on.pdf
PY  - 2025
SP  - 12
T2  - International Journal of Behavioral Nutrition & Physical Activity
TI  - Effects of movement behaviors on preschoolers' cognition: a systematic review of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1186%2fs12966-025-01705-y
UR  - https://ijbnpa.biomedcentral.com/counter/pdf/10.1186/s12966-025-01705-y.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - **Purpose**: This study aims to systematically review and summarize the empirical evidence on the effectiveness of cognitive behavioral and Adlerian play therapy for children aged 3-12 years. **Methods**: In this context, experimental studies examining the efficacy of play therapies published in peer-reviewed journals in the English language in EBSCOhost, PubMed, Science Direct, Scopus, and Web of Science databases between 2003 and 2023 were reviewed. **Results**: The findings indicate that play therapies are effective in addressing children's externalized and internalized behavior problems as well as language impairments. However, their impact on executive function and memory varied. **Conclusions**: Following an evaluation of the risk of bias in the included studies, it was concluded that cognitive behavioral and Adlerian play therapies effectively cope with problem behaviors and support cognitive functions in children. The strengths and weaknesses of the current study were discussed, and various suggestions were made for the future.
AN  - WOS:001436440000001
AU  - Fidan,
AU  - B.
AU  - S.
AU  - Dogmus,
AU  - Y.
AU  - U.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - 10.1177/10497315251316182
L1  - internal-pdf://4027603114/sertkaya-fidan-ulusoy-dogmus-2025-the-effectiv.pdf
PY  - 2025
SP  - 20
T2  - Research on Social Work Practice
TI  - The Effectiveness of Cognitive Behavioral and Adlerian Play Therapies in Children Aged 3-12 Years: A Systematic Literature Review
UR  - <Go to ISI>://WOS:001436440000001
UR  - https://journals.sagepub.com/doi/10.1177/10497315251316182
ER  -
TY  - JOUR
AB  - This review aims to evaluate the effectiveness of mindfulness-based interventions in improving the mental health of parents of children with intellectual and developmental disabilities (IDDs), specifically focusing on outcomes such as parental stress, anxiety, depression, and parent-child relationships. A systematic search was conducted across multiple databases, including Web of Science, PubMed, Embase, and others, up to December 2024. Two reviewers independently screened studies, extracted data, and assessed bias risk using the Cochrane Risk of Bias tool. Studies involving parents of children with intellectual or developmental disabilities who received mindfulness-based interventions and reported psychological outcomes were included. The meta-analysis was conducted using Review Manager 5.4 software, with a random effects model applied. This systematic review included 15 studies (1124 participants), of which 14 were used for meta-analysis (1078 participants). The results indicate that mindfulness-based interventions reduced the stress levels [SMD = - 0.26, 95% CI (- 0.49, - 0.04)], depressive symptoms [SMD = - 0.37, 95% CI (- 0.66, - 0.08)], distress [SMD = - 0.26, 95% CI (- 0.43, - 0.09)] and anxiety symptoms[SMD = - 0.35, 95% CI (- 0.66, - 0.04)] of parents of children with IDDs, while also improving parent-child relationships [SMD = - 0.32, 95% CI (- 0.05, - 0.58)], although the effects were moderate. Subgroup analyses revealed that interventions lasting 8 weeks or more [SMD =- 0.41, 95% CI (-0.67, -0.14)] and those targeting only the parents [SMD = - 0.26, 95% CI (- 0.44, - 0.08)] showed some positive effects in improving parent-child relationships or parent stress. Mindfulness-based interventions appear to have a positive effect on improving the mental health of parents of children with IDDs. However, the evidence of their effectiveness in enhancing parental mindfulness remains inconclusive. Future studies should consider the key factors influencing intervention implementation and optimize the design of large-scale randomized controlled trials to systematically and comprehensively assess the effectiveness and applicability of mindfulness-based interventions.
AN  - 40080346
AU  - Yang,
AU  - T.
AU  - Wang,
AU  - Y.
AU  - Xu,
AU  - P.
AU  - Tao,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1007/s10803-025-06790-3
L1  - internal-pdf://1047353483/Yang-2025-The Effectiveness of Mindfulness-Bas.pdf
PY  - 2025
SP  - 13
T2  - Journal of Autism & Developmental Disorders
TI  - The Effectiveness of Mindfulness-Based Interventions in Improving the Mental Health of Parents of Children with Intellectual or Developmental Disabilities: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs10803-025-06790-3
UR  - https://link.springer.com/article/10.1007/s10803-025-06790-3
UR  - https://link.springer.com/content/pdf/10.1007/s10803-025-06790-3.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - **Background**: Attention-deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children, often accompanied by working memory deficits. Recently, exercise interventions have gained attention as a potential strategy to improve cognitive function in children with ADHD. However, the effects of different types of exercise on working memory remain unclear. This study aimed to assess the effects of various exercise interventions on working memory in children with ADHD using a network meta-analysis. **Methods**: A comprehensive search was conducted in PubMed, Cochrane, Embase, and Web of Science databases for relevant studies. After screening according to the inclusion and exclusion criteria, a total of 17 eligible studies were identified for analysis. A network meta-analysis was performed to integrate data and evaluate the effects of cognitive-aerobic exercise, ball games, mind-body exercises, interactive games, and general aerobic exercise on working memory in children with ADHD. **Results**: The results indicated significant differences in the effectiveness of various types of exercise interventions on working memory in children with ADHD. Cognitive-aerobic exercise showed the most significant effect (SMD = 0.72, 95% CI: 0.44-1.00), followed by ball games (SMD = 0.61, 95% CI: -0.12-1.35). Mind-body exercises and interactive games had moderate effects (SMD = 0.50 and 0.37, respectively), while general aerobic exercise showed relatively small effects (SMD = 0.40, 95% CI: 0.19-0.60). SUCRA analysis further confirmed the highest preference for cognitive-aerobic exercise in improving working memory. Meta-regression analysis showed that intervention frequency and total intervention duration significantly affected the effectiveness of cognitive-aerobic exercise, while other variables did not significantly moderate the effects. **Conclusion**: Cognitive-aerobic exercise had the most significant effect on improving working memory in children with ADHD. Higher intervention frequency and longer intervention duration may enhance its effects. Future research should explore the impact of these factors and consider increasing sample sizes to validate the role of these moderators. **Systematic review registration**: https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=627915.
AN  - 39931282
AU  - Song,
AU  - X.
AU  - Hou,
AU  - Y.
AU  - Shi,
AU  - W.
AU  - Wang,
AU  - Y.
AU  - Fan,
AU  - F.
AU  - Hong,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fpsyg.2025.1522944
L1  - internal-pdf://2919103411/Song-2025-Exploring the impact of different ty.pdf
PY  - 2025
SP  - 1522944
T2  - Frontiers in Psychology
TI  - Exploring the impact of different types of exercise on working memory in children with ADHD: a network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.3389%2ffpsyg.2025.1522944
UR  - https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2025.1522944/pdf
VL  - 16
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Self-harm is common in adolescents and a major public health concern. Evidence for effective interventions that stop repetition is lacking. This individual-participant-data (IPD) meta-analysis of randomised controlled trials (RCTs) aimed to provide robust estimates of therapeutic intervention effects and explore which treatments are best suited to different subgroups. **METHOD**: We searched databases and trial registers, to January-2022. RCTs compared therapeutic intervention to control, targeted adolescents aged 11-18 with a history of self-harm and receiving clinical care and reported on outcomes related to self-harm or suicide attempt. Primary outcome was repetition of self-harm at 12 months post-randomization . Two-stage random-effects IPD meta-analyses were conducted overall and by intervention. Secondary analyses incorporated aggregate data (AD) from RCTs without IPD. PROSPERO registration: CRD42019152119. **RESULTS**: We identified 39 eligible studies; 26 provided IPD (3,448 participants), 7 provided AD (698 participants). There was no evidence that intervention/s were more or less effective than controls at preventing repeat self-harm by 12 months in IPD (odds ratio (OR)=1.06 [95% CI 0.86, 1.31], studies=20, n=2,949) or IPD+AD (OR=1.02 [95% CI 0.82, 1.27], studies=22, n=3,117) meta-analyses and no evidence of heterogeneity of treatment effects on study and treatment factors. Across all interventions, participants with multiple prior self-harm episodes showed evidence of improved treatment effect on self-harm repetition 6-12 months after randomization (OR=0.33 [95% CI 0.12, 0.94], studies=9, n=1,771). **CONCLUSION**: This large-scale meta-analysis of RCTs provided no evidence that therapeutic intervention was more, or less, effective than control for reducing repeat self-harm. We observed evidence indicating more effective interventions within youth with two or more self-harm incidents. Funders and researchers need to agree on a core set of outcome measures to include in subsequent studies.
AN  - 39892472
AU  - Wright-Hughes,
AU  - A.
AU  - Farrin,
AU  - A.
AU  - J.
AU  - Fonagy,
AU  - P.
AU  - Ougrin,
AU  - D.
AU  - Stahl,
AU  - D.
AU  - Wright,
AU  - J.
AU  - Irving,
AU  - D.
AU  - Mughal,
AU  - F.
AU  - Truscott,
AU  - A.
AU  - Diggins,
AU  - E.
AU  - Chanen,
AU  - A.
AU  - Cooney,
AU  - E.
AU  - Carter,
AU  - G.
AU  - Clover,
AU  - K.
AU  - Dadds,
AU  - M.
AU  - Diamond,
AU  - G.
AU  - Esposito-Smythers,
AU  - C.
AU  - Green,
AU  - J.
AU  - Griffiths,
AU  - H.
AU  - Hassanian-Moghaddam,
AU  - H.
AU  - Hatcher,
AU  - S.
AU  - Hazell,
AU  - P.
AU  - Husein,
AU  - N.
AU  - Kaess,
AU  - M.
AU  - King,
AU  - C.
AU  - Morthorst,
AU  - B.
AU  - O'Connor,
AU  - R.
AU  - C.
AU  - Santamarina-Perez,
AU  - P.
AU  - Tyrer,
AU  - P.
AU  - Walwyn,
AU  - R.
AU  - Cottrell,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.jaac.2025.01.017
L1  - internal-pdf://3640202456/1-s2.0-S0890856725000474-main.pdf
PY  - 2025
SP  - 28
T2  - Journal of the American Academy of Child & Adolescent Psychiatry
TI  - Systematic Review and Individual Participant Data Meta-Analysis: Reducing Self-Harm in Adolescents: Pooled Treatment Effects, Study, Treatment and Participant Moderators
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.jaac.2025.01.017
UR  - https://www.sciencedirect.com/science/article/pii/S0890856725000474?via%3Dihub
VL  - 28
ER  -
TY  - JOUR
AB  - Promoting bidirectional development between typically developing children and children with disabilities in inclusive preschool education is a critical yet underexplored area. Employing a meta-analysis methodology, this study examined this question by incorporating 15 experiment studies that met the established criteria, resulting in the generation of 33 independent effect sizes from a total of 1268 participants. The results from the random-effects model demonstrate a positive and favourable impact of inclusive preschool education on children's development (SMD = 0.583). The moderation analysis results indicate that the impact of inclusive education on children's development is significantly moderated by children's age group and the type of children, while the activity domain and intervention approach do not exhibit significant moderation effects.
AN  - WOS:001398951000001
AU  - Wang,
AU  - L.
AU  - Lei,
AU  - Y.
AU  - X.
AU  - Zhou,
AU  - Q.
AU  - Wei,
AU  - Y.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1080/13603116.2025.2449848
L1  - internal-pdf://4238802577/Wang-2025-Impact of inclusive education on ear.pdf
PY  - 2025
SP  - 16
T2  - International Journal of Inclusive Education
TI  - Impact of inclusive education on early childhood development: a systematic review and meta-analysis
UR  - <Go to ISI>://WOS:001398951000001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/13603116.2025.2449848
ER  -
TY  - JOUR
AB  - **LAY ABSTRACT**: Sleep disorders are common in people on the autistic spectrum and can affect their development, daily function, and overall well-being. This study examined the effectiveness of non-pharmacological intervention to improve sleep in autistic children and adolescents without intellectual disability. We considered 11 studies of non-pharmacological treatments for autistic children and adolescents. The results indicate that these interventions help to improve several sleep parameters, either by increasing, for example, the total time and quality of sleep, or by reducing the time needed for falling asleep. These approaches offer important treatment options especially for those cases where medication is not feasible, allowing physicians and specialists to propose more targeted and safer solutions for managing sleep difficulties in this population.
AN  - 39968574
AU  - Vargas,
AU  - C.
AU  - Paoletti,
AU  - D.
AU  - De
AU  - Stasio,
AU  - S.
AU  - Berenguer,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1177/13623613251319391
L1  - internal-pdf://4044874990/vargas-et-al-2025-sleep-disturbances-in-autist.pdf
PY  - 2025
SP  - 13623613251319391
T2  - Autism
TI  - Sleep disturbances in autistic children and adolescents: A systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1177%2f13623613251319391
UR  - https://journals.sagepub.com/doi/10.1177/13623613251319391
ER  -
TY  - JOUR
AB  - Positive psychological interventions (PPI) hold promise for boosting well-being and quality of life in diverse populations, but not much is known about their efficacy as ecological momentary interventions (EMIs, e.g. via mobile applications) in daily life. This meta-analysis uses random-effects models to examine the efficacy of PPI-EMIs compared to control groups (active or passive) and exploring study region, age, gender, and risk of bias as moderators. Overall, 16 studies were included (N = 3397, 69.1% female, M<sub>age</sub> = 21.87, SD = 13.02). We observed clinically significant effects in favor of the intervention for positive affect at posttest (k = 6; g = 0.29; p = 0.05) and well-being at follow-up (k = 5; g = 0.21; p = 0.13). No significant moderator effects were found. The number of studies was small for each outcome, risk of bias was mixed, and heterogeneity of effects was moderate to high for most outcomes.
AN  - 39930901
AU  - Tomczyk,
AU  - S.
AU  - Ewert,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1111/aphw.70006
L1  - internal-pdf://3558859264/Tomczyk-2025-Positive changes in daily life_ A.pdf
PY  - 2025
SP  - e70006
T2  - Applied Psychology: Health and Well-Being
TI  - Positive changes in daily life? A meta-analysis of positive psychological ecological momentary interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1111%2faphw.70006
UR  - https://iaap-journals.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/aphw.70006?download=true
VL  - 17
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) of behavioural and psychological interventions for managing paediatric obesity. **METHODS**: Eligible studies, published between 1985 and 2022, included 0 to 18 year olds with outcomes reported >=3 months post-baseline, including patient-reported outcome measures (PROMs), cardiometabolic and anthropometric outcomes, and adverse events (AEs). We pooled data using a random effects model and assessed certainty of evidence (CoE) related to minimally important difference estimates for outcomes using GRADE. **RESULTS**: We included 73 unique RCTs (n = 6305 participants, 53% female). Intervention types included physical activity (n = 1437), nutrition (n = 447), psychological (n = 1336), technology-based (n = 901) or multicomponent (>=2 intervention types, n = 2184). Physical activity had a small effect on health-related quality of life (HRQoL), varying effects ranging from moderate to very large on blood pressure, lipids and insulin resistance, and a small effect on BMIz. Nutrition had a small effect on lipids, insulin resistance and BMIz. Psychological interventions showed a small effect on HRQoL and triglycerides and moderate benefits on depressive symptoms, while technology interventions showed small benefits on blood pressure and BMIz. Multicomponent interventions had a large benefit on anxiety, small benefit on depressive symptoms, with large to very large benefits on lipids, and small benefits for diastolic blood pressure, insulin resistance and BMIz. AEs were reported infrequently, and when reported, were described as mild. **CONCLUSION**: Physical activity and multicomponent interventions showed improvements in PROMs, cardiometabolic and anthropometric outcomes. Future trials should consistently measure PROMs, evaluate outcomes beyond the intervention period, and study children <6 years of age.
AN  - 39823182
AU  - Henderson,
AU  - M.
AU  - Moore,
AU  - S.
AU  - A.
AU  - Harnois-Leblanc,
AU  - S.
AU  - Johnston,
AU  - B.
AU  - C.
AU  - Fitzpatrick-Lewis,
AU  - D.
AU  - Usman,
AU  - A.
AU  - M.
AU  - Sherifali,
AU  - D.
AU  - Merdad,
AU  - R.
AU  - Rigsby,
AU  - A.
AU  - M.
AU  - Esmaeilinezhad,
AU  - Z.
AU  - Morrison,
AU  - K.
AU  - M.
AU  - Hamilton,
AU  - J.
AU  - Ball,
AU  - G.
AU  - D.
AU  - C.
AU  - Birken,
AU  - C.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1111/ijpo.13193
L1  - internal-pdf://4092657654/Henderson-2025-Effectiveness of behavioural an.pdf
PY  - 2025
SP  - e13193
T2  - Pediatric Obesity
TI  - Effectiveness of behavioural and psychological interventions for managing obesity in children and adolescents: A systematic review and meta-analysis framed using minimal important difference estimates based on GRADE guidance to inform a clinical practice guideline
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1111%2fijpo.13193
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijpo.13193?download=true
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Understanding the mechanisms of change and between-family differences in behavioural parenting interventions for children with attention-deficit/hyperactivity disorder (ADHD) may help personalise interventions. Therefore, we examined whether improvements in parenting are associated with changes in child behaviour and functional outcomes, and how these associations vary based on parents' baseline parenting levels. **METHODS**: We collected individual participant data including 19 randomised controlled trials focusing on children with ADHD (n = 1,720). Immediate post-intervention measures of child ADHD and oppositional behaviour severity, reported by parents and functional impairment reported by either the parent or probably masked clinicians, were treated as outcomes. We estimated pathways from intervention (vs. control) to child outcomes, via immediate post-intervention parent reports of constructive parenting (e.g. praise), non-constructive parenting (e.g. physical punishment) and parent-child affection (e.g. warmth), while controlling for baseline values of both child outcomes and parenting levels. Baseline values of each parenting variable were used as moderators of the mediated pathways. **RESULTS**: Improvements in parenting behaviours and parent-child affection immediately following the intervention jointly explained concurrent improvements in children's ADHD severity, oppositional behaviour and functional impairment. Furthermore, when reversing the direction of the pathways, improvements in all child outcomes jointly explained improvements in each aspect of parenting. Improvements in non-constructive parenting and parent-child affection uniquely accounted for intervention effects on functional impairment, especially for families with higher baseline levels of non-constructive parenting. **CONCLUSIONS**: Our findings might indicate that improvements in both the behavioural and affective aspects of parenting are associated with concurrent reductions in child behaviour problems and functional impairment. However, more research is necessary to explore the potential causal directionality between parenting and child outcomes. Nonetheless, supporting families with poorer parenting skills may be especially important, as reductions in non-constructive parenting in these families are linked to stronger treatment effects on child functional impairment.
AN  - 39910778
AU  - Psyllou,
AU  - C.
AU  - Luman,
AU  - M.
AU  - van
AU  - den
AU  - Hoofdakker,
AU  - B.
AU  - J.
AU  - Van
AU  - der
AU  - Oord,
AU  - S.
AU  - Aghebati,
AU  - A.
AU  - Boyer,
AU  - B.
AU  - Buitelaar,
AU  - J.
AU  - Chronis-Tuscano,
AU  - A.
AU  - Daley,
AU  - D.
AU  - Dekkers,
AU  - T.
AU  - J.
AU  - DuPaul,
AU  - G.
AU  - J.
AU  - Fabiano,
AU  - G.
AU  - A.
AU  - Ferrin,
AU  - M.
AU  - Franke,
AU  - N.
AU  - Tsahor,
AU  - N.
AU  - G.
AU  - Harvey,
AU  - E.
AU  - Hennig,
AU  - T.
AU  - Herbert,
AU  - S.
AU  - Hoekstra,
AU  - P.
AU  - J.
AU  - Kern,
AU  - L.
AU  - Mautone,
AU  - J.
AU  - A.
AU  - Mikami,
AU  - A.
AU  - Y.
AU  - Normand,
AU  - S.
AU  - Pfiffner,
AU  - L.
AU  - J.
AU  - Shimabukuro,
AU  - S.
AU  - Schramm,
AU  - S.
AU  - A.
AU  - Schweitzer,
AU  - J.
AU  - B.
AU  - Sibley,
AU  - M.
AU  - H.
AU  - Sonuga-Barke,
AU  - E.
AU  - Thompson,
AU  - C.
AU  - Thompson,
AU  - M.
AU  - J.
AU  - Tripp,
AU  - G.
AU  - Webster-Stratton,
AU  - C.
AU  - Xie,
AU  - Y.
AU  - Leijten,
AU  - P.
AU  - Groenman,
AU  - A.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1111/jcpp.14120
L1  - internal-pdf://1697385033/Psyllou-2025-Research Review_ Mechanisms of ch.pdf
PY  - 2025
SP  - 05
T2  - Journal of Child Psychology & Psychiatry & Allied Disciplines
TI  - Research Review: Mechanisms of change and between-family differences in parenting interventions for children with ADHD - an individual participant data meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1111%2fjcpp.14120
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.14120?download=true
VL  - 05
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Traditional and non-traditional strategies have been employed to improve youth health. Dog-assisted interventions have been proposed as a novel strategy to regulate stress and its consequences across all age groups. This systematic review and multilevel meta-analysis assessed the influence of dog-assisted interventions on cortisol levels in youth and explored potential moderators. **SOURCES**: We conducted a comprehensive systematic search across multiple databases, including PubMed, Scopus, Web of Science, Cochrane Library, and ScienceDirect, up to June 17, 2024, to evaluate the impact of dog-assisted interventions on youth cortisol levels. Two reviewers independently extracted and verified data from eligible randomized clinical trials, with a third reviewer ensuring accuracy. Cochrane's RoB 2.0 tool was used to assess the risk of bias. Heterogeneity was analyzed using Q and I<sup>2</sup> statistics. A random-effects model was employed to calculate effect sizes (ES) using R software. **SUMMARY OF THE FINDINGS**: Significant cortisol reductions were found for interventions lasting >15 min (ES: 0.65; p = .038), with a non-significant trend towards reduced cortisol in non-medical settings (ES: 0.46; p = .070). No significant effects were observed for shorter interventions, different control groups, or age-specific analyses. Meta-regression analysis revealed significant differences, showing better outcomes with longer intervention times and fewer female participants. **CONCLUSION**: Dog-assisted interventions lasting >15 min seem to be a promising and non-traditional strategy for regulating cortisol levels in children and adolescents in stressful situations. This study outlines gaps in the research and future directions.
AN  - 39951871
AU  - Pena-Jorquera,
AU  - H.
AU  - Hernandez-Jana,
AU  - S.
AU  - Sanchez-Martinez,
AU  - J.
AU  - Espinoza-Puelles,
AU  - J.
AU  - P.
AU  - Martinez-Flores,
AU  - R.
AU  - Barreto-Schuch,
AU  - F.
AU  - Yanez-Sepulveda,
AU  - R.
AU  - Delgado-Floody,
AU  - P.
AU  - Ferrari,
AU  - G.
AU  - Sadarangani,
AU  - K.
AU  - P.
AU  - Cancino-Lopez,
AU  - J.
AU  - Bento-Torres,
AU  - J.
AU  - Espinoza-Salinas,
AU  - A.
AU  - Stamatakis,
AU  - E.
AU  - Cristi-Montero,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.socscimed.2025.117815
L1  - internal-pdf://1914707737/1-s2.0-S0277953625001443-main.pdf
PY  - 2025
SP  - 117815
T2  - Social Science & Medicine
TI  - Dog companionship and cortisol levels in youth. A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.socscimed.2025.117815
UR  - https://www.sciencedirect.com/science/article/pii/S0277953625001443?via%3Dihub
VL  - 369
ER  -
TY  - JOUR
AB  - **AIM**: This study aims to compare and rank the effects of acoustic stimulation on painful procedures in both preterm and full-term infants. **METHODS**: Six databases including Medline, Web of Science, the Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature, Embase, and SinoMed, were searched from inception to July, 2023. A Bayesian network meta-analysis with random effects models was performed using R software and Stata 15.0. The quality of included studies was assessed using the Cochrane Collaboration's tool. The study protocol was registered at PROSPERO (Registration number: CRD42023451102). **RESULTS**: A total of 28 studies involving 2624 preterm and full-term infants were included and 8 acoustic stimulation interventions were identified. Regarding pain levels during procedures, maternal voice, maternal voice plus, music therapy and maternal voice plus, music therapy plus, other pharmaceutical interventions, vocal music therapy, white noise, and white noise plus were significantly more effective than control group [standardized mean differences (SMD) ranged from -2.6 to -0.87]. White noise plus was the most effective intervention for reducing pain levels during procedures (90.6 %). Regarding pain levels after procedures (no specific time mentioned), maternal voice, maternal voice plus, music therapy and maternal voice plus, music therapy plus, other pharmaceutical interventions, other non-pharmaceutical interventions, routine care, vocal music therapy, and white noise plus were significantly more effective than control group (SMD ranged from -4.7 to -1.6). Music therapy and maternal voice plus was the most effective intervention for reducing pain levels after procedures, without specific time mentioned (95.29 %). Regarding pain levels 1 min after procedures, only music therapy plus and other pharmaceutical interventions were effective (SMD ranged from -4.5 to -4.9) and music therapy plus was the most effective intervention (93.41 %). No interventions had significant effects on pain levels 3, 5, and 10 min after procedures. Regarding heart rate, only white noise plus could provide a lower increase during procedures. For oxygen saturation, only vocal music therapy could provide a lower decrease after painful procedures (no specific time mentioned). No interventions had significant effects on stabilizing respiratory rate. **CONCLUSION**: This review suggests that multiple acoustic stimulation interventions are effective for pain relief in both preterm and full-term infants undergoing painful procedures. More high quality studies with larger sample size are required to generate evidence regarding the short- and long-term effectiveness and safety of acoustic stimulation interventions on painful procedures.
AN  - 40048939
AU  - Ding,
AU  - S.
AU  - Wang,
AU  - Q.
AU  - Fu,
AU  - X.
AU  - Huang,
AU  - X.
AU  - Liao,
AU  - L.
AU  - Zhang,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.ijnurstu.2025.105031
L1  - internal-pdf://0658987132/Ding_2025.pdf
PY  - 2025
SP  - 105031
T2  - International Journal of Nursing Studies
TI  - Effects of acoustic stimulation on painful procedures in preterm and full-term infants: A systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1016%2fj.ijnurstu.2025.105031
UR  - https://www.sciencedirect.com/science/article/pii/S0020748925000409?via%3Dihub
VL  - 165
ER  -
TY  - JOUR
AB  - **AIM**: To evaluate the effectiveness of social robots in reducing pain, stress, and anxiety among hospitalised children. **BACKGROUND**: Children are often subjected to painful medical procedures during hospitalisation, resulting in pain, stress and anxiety. This can have significant implications for a child's psychological and overall well-being. Therefore, it is essential to alleviate these emotions among hospitalised children. **METHODS**: The review included studies involving hospitalised children ages 1-12 who underwent any medical procedure and received interventions involving social robots. Six databases were searched for articles published on the review topic. The search timeline was from January 2013 to January 2024. The included studies need to assess the effectiveness of the robots in improving primary outcomes such as pain, stress, distress, or anxiety levels. A meta-analysis of these variables was conducted. **RESULTS**: The meta-analysis of 313 participants found that social robots had a standardised mean difference (SMD) of -0.10 (95 % CI: -0.41 to 0.22, P = 0.54) in reducing pain, indicating no significant effect. For stress and distress, with a total of 309 participants, the SMD was -0.33 (95 % CI: -0.62 to -0.03, P = 0.003), and for anxiety, including 335 participants, the SMD was -0.42 (95 % CI: -0.73 to -0.10, P = 0.09). These findings suggest that while social robots are not effective in reducing pain, however, they are effective in lowering stress and anxiety levels in hospitalised children undergoing painful medical procedures. **CONCLUSION**: This review highlights the efficacy of social robots when introduced to hospitalised children who are undergoing painful medical procedures. Nurses could consider integrating social robots into patient care protocols, which would yield advantages for anxious young children and their parents, as social robots help improving the child's psychological and overall well-being during medical procedures.
AN  - 39965262
AU  - Or,
AU  - X.
AU  - Y.
AU  - Ng,
AU  - Y.
AU  - X.
AU  - Goh,
AU  - Y.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.pedn.2025.01.032
L1  - internal-pdf://2712997347/1-s2.0-S0882596325000430-main.pdf
PY  - 2025
SP  - 11-20
T2  - Journal of Pediatric Nursing
TI  - Effectiveness of social robots in improving psychological well-being of hospitalised children: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.pedn.2025.01.032
UR  - https://www.sciencedirect.com/science/article/pii/S0882596325000430?via%3Dihub
VL  - 82
ER  -
TY  - JOUR
AB  - **Background**: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by social impairments, sensory processing issues, repetitive behavior patterns, motor abnormalities, and executive function impairments. **Objective**: To systematically review and meta-analyze the effects of various exercise modalities on flexibility and cognitive control, social skills, behavioral problems, motor skills, and coordination in children with ASD, providing scientific evidence for clinical practice to guide effective exercise interventions for children with ASD. **Methods**: Literature searches were conducted in PubMed, EMbase, Cochrane Library, EBSCOhost, and Web of Science databases, covering the period from database inception to February 15, 2024. Inclusion criteria included studies involving children with ASD, any form of exercise intervention, reporting at least one ASD-related outcome, and designed as randomized controlled trials (RCTs) or quasi-experimental studies. Exclusion criteria included reviews, conference abstracts, commentary articles, and studies lacking sufficient statistical data for meta-analysis. Study quality was assessed using the PEDro scale. Effect sizes were calculated using standardized mean differences (SMD). Heterogeneity was assessed with the I <sup>2</sup> statistic. Multiple subgroup analyses were conducted, and publication bias was evaluated using Begg's Test and Egger's Test. **Results**: 23 RCTs were included in this study, showing positive effects of exercise interventions in various domains.Upper grade students showed significant improvement in flexibility and cognitive control (SMD = -0.282, p = 0.161). Lower grade children showed the most significant improvement in motor skills and coordination (SMD = 0.475, p = 0.043). Preschool children showed significant enhancement in social skills (SMD = 0.312, p = 0.041). Behavioral problems improved significantly across all age groups (SMD = -0.674, p < 0.001). Martial arts and ball games were particularly effective in enhancing these domains, and appropriate periodic exercise interventions effectively improved various abilities in children with ASD. Results varied across different ages and intervention types. **Conclusion**: Exercise interventions significantly improve flexibility, cognitive control, motor skills, coordination, social skills, and behavioral problems in children with ASD. This study supports exercise interventions as an effective method to enhance multiple abilities in children with ASD and emphasizes the importance of designing personalized intervention programs tailored to different ages and needs. Future research should focus on larger sample sizes and long-term follow-ups to confirm the sustainability and generalizability of intervention effects.
AN  - 40083436
AU  - Wang,
AU  - Y.
AU  - Qian,
AU  - G.
AU  - Mao,
AU  - S.
AU  - Zhang,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.3389/fped.2025.1475019
L1  - internal-pdf://2709739597/Wang-2025-The impact of physical exercise inte.pdf
PY  - 2025
SP  - 1475019
T2  - Frontiers in Pediatrics
TI  - The impact of physical exercise interventions on social, behavioral, and motor skills in children with autism: a systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.3389%2ffped.2025.1475019
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11903732/pdf/fped-13-1475019.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - This meta-review provides the first meta-analytic evidence from published meta-analyses examining the effectiveness of acute exercise interventions on cognitive function. A multilevel meta-analysis with a random-effects model and tests of moderators were performed in R. Thirty systematic reviews with meta-analyses (383 unique studies with 18,347 participants) were identified. Acute exercise significantly improved cognitive function with a small-to-medium effect (N of standardized mean difference [SMD] = 44, mean SMD [M SMD] = 0.33, 95% CI [0.24, 0.42], p < .001). A generalized effect was observed across cognitive domains, showing benefits to tasks identified as attention (M SMD = 0.37), mixed/other (M SMD = 0.36), executive function (M SMD = 0.36), memory (M SMD = 0.23), and information processing (M SMD = 0.20). The timepoint of assessment was a significant moderator (p < .05) with the largest benefits observed when cognitive function was assessed following exercise (M SMD = 0.32). Sample descriptors (i.e., age, cognitive status) and exercise parameters (i.e., intensity, type, duration) did not moderate the positive acute exercise effect on cognitive function (ps > .05). Acute exercise facilitates cognitive function, with the size of the effect varying depending on the timing of assessment in relation to exercise. Notably, these benefits are evident across cognitive domains and occur regardless of participants' characteristics and exercise settings, supporting the adoption of acute exercise for improved cognitive function across the lifespan.
AN  - WOS:001410114400001
AU  - Chang,
AU  - Y.
AU  - K.
AU  - Ren,
AU  - F.
AU  - F.
AU  - Li,
AU  - R.
AU  - H.
AU  - Ai,
AU  - J.
AU  - Y.
AU  - Kao,
AU  - S.
AU  - C.
AU  - Etnier,
AU  - J.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1037/bul0000460
L1  - internal-pdf://1705516200/Chang_2025.pdf
PY  - 2025
SP  - 21
T2  - Psychological Bulletin
TI  - Effects of Acute Exercise on Cognitive Function: A Meta-Review of 30 Systematic Reviews With Meta-Analyses
UR  - <Go to ISI>://WOS:001410114400001
ER  -
TY  - JOUR
AB  - **Background**: Self-harm in adolescents is an international concern. Evidence highlights that therapeutic intervention (TI), such as cognitive behaviour therapy informed treatments, after self-harm leads to reduced self-harm repetition. However, there is no prior literature about the effects of TI on future mortality in adolescents. We examined the effect of TI on mortality rates in adolescents across RCTs. **Methods**: This review was reported in accordance with PRISMA guidance. MEDLINE, EMBASE, PsycINFO, and Cochrane Library were searched to 19 June 2024. Two authors independently screened titles, abstracts, and full texts against pre-defined criteria. RCTs were included if they compared a TI versus a comparator in adolescents up to 18 years with at least one prior self-harm episode. There was no lower age limit. For the pooled effect size of mortality, the DerSimonian-Laird method was used, and a random effects model for self-harm and suicide attempts. The primary outcome was intra or post-trial mortality in adolescent post TI, and the effect of TIs on self-harm including attempted suicide episodes were secondary outcomes. Analyses were done in Stata. **Results**: Twenty-four trials of TIs consisting of 3470 randomised adolescents were included. The pooled risk difference for mortality of participants in the TI group was 0.002 (95% CI -0.003 to 0.008, p = 0.42). There were 6 deaths in the TI group compared to 15 deaths in the comparator group. The pooled risk difference for TI on repeat self-harm was -0.07 (95% CI -0.132 to -0.007, p = 0.028), and -0.05 (95% CI -0.086 to -0.007, p = 0.022) for suicide attempts compared to comparator. **Conclusions**: This review found no significant impact of TIs on future mortality in adolescents. We also demonstrated that TIs can reduce suicide attempts which can lead to substantial benefits for adolescents, families, and clinical services.
AN  - WOS:001402597200001
AU  - Mughal,
AU  - F.
AU  - Young,
AU  - P.
AU  - Stahl,
AU  - D.
AU  - Asarnow,
AU  - J.
AU  - R.
AU  - Ougrin,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/jcv2.12302
L1  - internal-pdf://0567738501/Mughal-2025-Mortality in adolescents after the.pdf
PY  - 2025
SP  - 16
T2  - Jcpp Advances
TI  - Mortality in adolescents after therapeutic intervention for self-harm: A systematic review and meta-analysis
UR  - <Go to ISI>://WOS:001402597200001
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: To perform a systematic review and meta-analysis of randomized controlled trials (RCTs) of behavioral interventions for sleep disruption in children with neurodevelopmental and medical conditions. **METHODS**: A comprehensive literature search was designed and run for studies published between 1970 and July 1, 2023. Original, peer-reviewed RCTs of children ages birth to 18 years with/at risk for sleep disruption and a neurodevelopmental and/or medical condition were included. Interventions without behavioral components, lifestyle interventions, or pharmaceutical interventions were excluded. Primary outcomes included sleep health domains, and secondary outcomes were condition symptomatology and quality of life. **RESULTS**: Data from 15 RCTs were examined (1,374 participants, 78% male, 71% White). Sleep disruptions were predominantly insomnia symptoms. Intervention content included parent training, sleep hygiene education, and relaxation strategies. Adaptations to the interventions for use in children with neurodevelopmental and/or medical conditions included behavioral strategies commonly used in those conditions, sleep education specific to the condition, and/or use of case examples specific to the condition. No studies reported on adverse effects. Behavioral sleep interventions had a significant effect on sleep satisfaction, bedtime resistance, and ADHD symptoms at postintervention. At follow-up, effects were maintained only for sleep satisfaction. Parent rating of child sleep duration improved at follow-up but not postintervention. **CONCLUSIONS**: Despite being at high risk for comorbid sleep disruption, children with neurodevelopmental and/or medical conditions are underrepresented in the sleep intervention literature. Future research is needed with larger, more diverse samples and increased methodological rigor to address sleep disruption in these pediatric populations. **PROTOCOL REGISTRATION**: Open Science Framework Preregistration doi.org/10.17605/OSF.IO/KE58C, date of registration December 9, 2023.
AN  - 39932204
AU  - Kamara,
AU  - D.
AU  - Bernard,
AU  - A.
AU  - Clark,
AU  - E.
AU  - L.
AU  - M.
AU  - Duraccio,
AU  - K.
AU  - M.
AU  - Ingram,
AU  - D.
AU  - G.
AU  - Li,
AU  - T.
AU  - Piper,
AU  - C.
AU  - R.
AU  - Cooper,
AU  - E.
AU  - Simon,
AU  - S.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1093/jpepsy/jsae096
L1  - internal-pdf://3620605739/Kamara-2025-Systematic review and meta-analysi.pdf
PY  - 2025
SP  - 11
T2  - Journal of Pediatric Psychology
TI  - Systematic review and meta-analysis of behavioral interventions for sleep disruption in pediatric neurodevelopmental and medical conditions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1093%2fjpepsy%2fjsae096
UR  - https://academic.oup.com/jpepsy/advance-article-abstract/doi/10.1093/jpepsy/jsae096/8008673?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/jsae096.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA34wggN6BgkqhkiG9w0BBwagggNrMIIDZwIBADCCA2AGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMmPxVCwWLG_mvOnSmAgEQgIIDMQPLu0RsGF1KDX04kFH71uGnA_VgGELzWcuJFiro1SXmVR-QYYF79gi6W02bZQZaSv4QuudSszRHlTKYluqeJfNOhknkpIhhqMUNz5UJCV-KWCI8xfnRBgGikAgqZoylqpMSXqwOCktZj1YPzm55RoM562KiMCAfivaAbVRPmBpLaNCe498HAitU25r_HrxEEI9DFZaQqsPdpvJyhaT_OMhBIl7LBykeMsGOew7IEf0b-8b63lVo_YpHfaYfvoAiroW2mWaS1I71tuGyTkb5rxGCg_tjXtlNv15o9l0cqdhQDm-LYqAYYLMXH0CIMx2lB5gV0bJzgwVwBEyBsBOMvr_G1y8O4bLMbPzDPc2lQ6n5cPI1qdjbJTCG_iemlBZfBkR-QynObu9je6WH72wYW_dZoetHyv-IYwmXUascu6n2r0qEzi7ZClUwxaN947UlwtWyKhz48hSSzZrIN3DSwLt2hTE4LxUEqtUZJ7HDz4MRCj39ZuQOLxarXhc34D8e_0Qn6mR1SVKxcJzj4_r0I5SlT0I1U-nTR6De3yHSYgUsTRsETRWqzWBQlfyYJL41hBvlS5xLNgkyyIVr_wm9jlonrZICHJgrH5YIfWU21qd7m9aEF__mzX4irunJqmEbffu9dJJg0be_ag2hrD_CTJ9fIP5R6R6cLMDTUXfK4jneogoF8zz247ZpKRTKAvDu8Etg3cPviV-82d20u3IzEevAd12_ejT20saxq9gEr-o7yYCl3igfQXuRSv-D4rk-PCYP6rw2l8UkEqAT7r190GIn6hkGLCAOdaAnY9T_1afuSCHr2LxgLNd0y3_b7260qtsIMAOh_TnyCoSTpvfmbUntMa5SyPOsgS-09r3Atswvamd48w3GRCgtzLvoxxazopoysxADKFF5wb5BYIiTxGIL-HOvUp7nYFZGw5rQo1-A6h3t_s4y4pMq2LBI4Yz5BBBf-0vw92Jv8-l4NllSHfFsvsY690KCbsB2dbHdxAuqu9evu3ZhAS5inrjt5rznASsg2Ko6bwl6yZF6GKJ4TsNXmmDjZROgazMl3GQ6T2bHwjJh00kB4FvjJJX1V6BkJKY
VL  - 11
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Effective management of neonatal pain and stress is crucial, with non-pharmacological approaches like maternal odor showing promise. However, mixed evidence exists on its efficacy. This study aims to comprehensively assess the effects of breast milk odor on pain and stress (primary outcomes) and on oxygen saturation (SpO2) and heart rate (secondary outcomes) in neonates. **METHODS**: A thorough search was conducted on PubMed, Cochrane, SID, Embase, and Google Scholar until January 14, 2025, without time restrictions. A meta-analysis was performed to compare outcomes between intervention and control groups, assessing heterogeneity using the I++2++ statistic and chi-squared test. A random effects model was applied for high heterogeneity (I++2++ >= 30%, p < 0.05), analyzing continuous outcomes with mean difference (MD) and standardized mean difference (SMD) at a 95% confidence interval (CI). Subgroup analyses were conducted based on newborn procedures and term status, along with meta-regression and sensitivity analyses. Trial Sequential Analysis (TSA) was employed to ensure reliable conclusions about the intervention effects, and the certainty of evidence was evaluated using GRADE. **RESULTS**: The systematic review included seven studies (RCT and quasi-experimental) revealing that breast milk odor significantly reduces pain responses in neonates (SMD: -1.60, 95% CI: -2.48, -0.72; I<sup>2</sup> = 94%; 7 trials; 478 neonates; low-certainty evidence). It also improved key physiological parameters, such as oxygen saturation (MD: 1.64, 95% CI: 0.49, 2.80; I<sup>2</sup> = 57%; 5 trials; 288 neonates; very low-certainty evidence) and heart rate (MD: -6.73, 95% CI: -12.33, -1.13; I++2++ = 78%; 5 trials; 288 neonates; very low-certainty evidence). Although a reduction in stress levels was noted, it did not reach statistical significance (MD: -0.64, 95% CI: -1.87, 0.59; I++2++ = 89%; 2 trials; 128 neonates; very low-certainty evidence). Meta-regression indicated a significant correlation between cesarean delivery rates and neonatal pain response (p = 0.010). TSA results confirmed the analysis was adequately powered for pain outcome. **CONCLUSION**: The review underscores the potential of breast milk odor as a non-pharmacological intervention for managing pain in neonates. However, the low to very low certainty of evidence calls for further research to validate these findings and improve neonatal care protocols.
AN  - 40011834
AU  - Laleh,
AU  - S.
AU  - S.
AU  - Inal,
AU  - S.
AU  - Maghalian,
AU  - M.
AU  - Mirghafourvand,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1186/s12887-025-05504-z
L1  - internal-pdf://0017557265/Laleh-2025-The effect of breast milk odor on i.pdf
PY  - 2025
SP  - 145
T2  - Bmc Pediatrics
TI  - The effect of breast milk odor on infant pain and stress levels: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1186%2fs12887-025-05504-z
UR  - https://bmcpediatr.biomedcentral.com/counter/pdf/10.1186/s12887-025-05504-z.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Physical activity interventions positively influence executive functions in both the general population and individuals with ADHD. However, there is limited research focusing on school-aged children, who have the highest ADHD diagnosis rates. This study aims to provide targeted intervention strategies for improving executive function in this population, offering a practical reference for selecting specific exercise types when designing interventions for children with ADHD. **METHODS**: A systematic search was conducted across PubMed, Embase, Web of Science, and the Cochrane Library to identify relevant RCTs up to September 2023. Two independent reviewers handled literature screening, data extraction, and quality assessment. Stata 15.1 software was used for the meta-analysis.**RESULTS**: The meta-analysis included 19 studies, revealing that physical activity interventions significantly improved executive functions in school-aged children with ADHD. Cognitive flexibility (SMD=0.70, 95% CI: 0.09, 1.31) and working memory (SMD=0.74, 95% CI: 0.20, 1.28) showed moderate to large effects, while inhibition switching had a small to medium effect (SMD=-0.35, 95% CI: -0.74, 0.03). Subgroup analysis indicated that cognitively engaging exercises were more effective, with intervention outcomes moderated by duration, frequency, and length. **LIMITATION**: Inconsistent measurement tools among the included studies may introduce biases. **CONCLUSIONS**: Physical activity interventions are effective in enhancing executive functions in school-aged children with ADHD. Cognitively engaging exercises show the most promise, especially when tailored by intervention duration, frequency, and length.
AN  - 40010649
AU  - Li,
AU  - D.
AU  - Miao,
AU  - C.
AU  - Wang,
AU  - D.
AU  - Li,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.jad.2025.01.155
L1  - internal-pdf://2979594951/1-s2.0-S0165032725001855-main.pdf
PY  - 2025
SP  - 24
T2  - Journal of Affective Disorders
TI  - Effect of physical activity interventions on executive functions in school-age children with ADHD: A meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.jad.2025.01.155
UR  - https://www.sciencedirect.com/science/article/pii/S0165032725001855?via%3Dihub
VL  - 24
ER  -
TY  - JOUR
AB  - A growing number of studies have examined the effects of group counseling on students' mental health or academic functioning in China; no meta-analysis of these studies has yet been conducted, which may limit school-based applicability or the development of service systems. This study sought to establish an overall effect size for group counseling interventions, as well as identify potential moderator variable effects on their efficacy for Chinese mainland adolescents in particular. A total of 611 studies, comprising 15,320 adolescent participants altogether, were included, with meta-analyses conducted for six mental health outcomes and five academic functioning outcomes. The results showed that, at posttest, group counseling had statistically significant medium to large effects on depression symptoms (standardized mean difference [SMD] = -0.835), anxiety symptoms (SMD = -0.722), loneliness (SMD = -0.791), sleep problems (SMD = -1.075), self-harm (SMD = -1.463), suicidal ideation (SMD = -1.055), learning motivation (SMD = 0.952), learning engagement (SMD = 1.478), academic self-efficacy (SMD = 1.264), academic procrastination (SMD = -1.528), and learning burnout (SMD = -1.591). The moderator results suggest that group counseling might work best as a small-scale intervention and that online intervention resulted in improvements comparable to face-to-face intervention. This study demonstrates that school-based group counseling effectively enhances both the mental health and academic functioning of Chinese adolescents. Our finding highlights the importance of such interventions in addressing psychological and educational challenges in schools, providing evidence for educators and policymakers to strengthen these support systems. Future research should explore how intervention components interact to optimize their impact in school settings. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
AN  - 39992753
AU  - Lin,
AU  - H.
AU  - Wang,
AU  - Y.
AU  - He,
AU  - G.
AU  - Li,
AU  - J.
AU  - Zheng,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1037/cou0000789
L1  - internal-pdf://3397979056/2025-84390-001.pdf
PY  - 2025
SP  - 24
T2  - Journal of Counseling Psychology
TI  - The effect of school-based group counseling on Chinese mainland adolescents' mental health and academic functioning: A meta-analysis of controlled studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1037%2fcou0000789
VL  - 24
ER  -
TY  - JOUR
AB  - **AIM**: Gender dysphoria (GD) refers to the psychological distress associated with the incongruence between one's sex and one's gender identity. To manage GD, individuals may delay the development of primary and secondary sex characteristics with the use of puberty blockers. In this systematic review, we assess and summarise the certainty of the evidence about the effects of puberty blockers in individuals experiencing GD. **METHODS**: We searched Medline, Embase, PsychINFO, Social Sciences Abstracts, LGBTQ+ Source and Sociological Abstracts from inception to September 2023. We included observational studies comparing puberty blockers with no puberty blockers in individuals aged <26 years experiencing GD, as well as before-after and case series studies. Outcomes of interest included psychological and physical outcomes. Pairs of reviewers independently screened articles, abstracted data and assessed risk of bias. We performed a meta-analysis and assessed the certainty of a non-zero effect using the grading of recommendations assessment, development and evaluation (GRADE) approach. **RESULTS**: We included 10 studies. Comparative observational studies (n=3), comparing puberty blockers versus no puberty blockers, provided very low certainty of evidence on the outcomes of global function and depression. Before-after studies (n=7) provided very low certainty of evidence addressing gender dysphoria, global function, depression, and bone mineral density. **CONCLUSIONS**: There remains considerable uncertainty regarding the effects of puberty blockers in individuals experiencing GD. Methodologically rigorous prospective studies are needed to understand the effects of this intervention. **TRIAL REGISTRATION NUMBER**: PROSPERO CRD42023452171.
AN  - 39855724
AU  - Miroshnychenko,
AU  - A.
AU  - Roldan,
AU  - Y.
AU  - Ibrahim,
AU  - S.
AU  - Kulatunga-Moruzi,
AU  - C.
AU  - Montante,
AU  - S.
AU  - Couban,
AU  - R.
AU  - Guyatt,
AU  - G.
AU  - Brignardello-Petersen,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1136/archdischild-2024-327909
L1  - internal-pdf://2070621128/Miroshnychenko-2025-Puberty blockers for gende.pdf
PY  - 2025
SP  - 30
T2  - Archives of Disease in Childhood
TI  - Puberty blockers for gender dysphoria in youth: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1136%2farchdischild-2024-327909
UR  - https://adc.bmj.com/content/archdischild/early/2025/01/29/archdischild-2024-327909.full.pdf
VL  - 30
ER  -
TY  - JOUR
AB  - **Importance**: Mental health stigma is a considerable barrier to help-seeking among young people. **Objective**: To systematically review and meta-analyze randomized clinical trials (RCTs) of interventions aimed at reducing mental health stigma in young people. **Data Sources**: Comprehensive searches were conducted in the CENTRAL, CINAHL, Embase, PubMed, and PsycINFO databases from inception to February 27, 2024. Search terms included "stigma," "mental health," "mental disorders," "adolescents," "youth," and "randomized controlled trial." **Study Selection**: Inclusion criteria encompassed RCTs involving interventions aimed at reducing mental health stigma among young people (aged 10-24 years). Studies had to report outcomes related to stigma or help-seeking behaviors. Exclusion criteria included grey literature and studies without results. **Data Extraction and Synthesis**: Data were extracted independently by 7 authors (M.A.C., D.N., F.B., S.C., A.I.L., J.C., V.M.) using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Risk of bias was assessed with the Cochrane risk-of-bias tool. Three-level multivariate meta-analyses were conducted to account for within-study correlations and to maximize data use. Standardized mean differences (SMDs) (Hedges g) and odds ratios (ORs) with 95% CIs were calculated. The data analysis was conducted from May 30 through July 4, 2024. **Main Outcomes and Measures**: Primary outcomes included stigma-related knowledge, attitudes, behaviors, and general stigma. Help-seeking outcomes were categorized into attitudes, intentions, and behaviors. Secondary outcomes included self-efficacy and empowerment. **Results**: A total of 97 studies were included in the systematic review, representing 43852 young people (mean [IQR] age, 18.7 [15.8-21.3] years; mean [IQR] females, 59.2% [49.4%-72.0%]), and 74 studies were included in 3-level multivariate meta-analyses. Significant short-term effect sizes were found for stigma-related knowledge (SMD, 0.66; 95% CI, 0.43-0.89), attitudes (SMD, 0.38; 95% CI, 0.20-0.56), behaviors (SMD, 0.29; 95% CI, 0.13-0.45), and general stigma (SMD, 0.20; 95% CI, 0.06-0.34) and for help-seeking attitudes (SMD, 0.18; 95% CI, 0.09-0.28) and intentions (SMD, 0.14; 95% CI, 0.07-0.21). Social contact interventions had a greater influence on stigma-related behaviors than did educational approaches. **Conclusions and Relevance**: These findings suggest that interventions to reduce mental health stigma among youth are beneficial in the short term. Further high-quality RCTs with long-term follow-up are needed to better understand and enhance these interventions' outcomes.
AN  - 39813031
AU  - Crockett,
AU  - M.
AU  - A.
AU  - Nunez,
AU  - D.
AU  - Martinez,
AU  - P.
AU  - Borghero,
AU  - F.
AU  - Campos,
AU  - S.
AU  - Langer,
AU  - A.
AU  - I.
AU  - Carrasco,
AU  - J.
AU  - Martinez,
AU  - V.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1001/jamanetworkopen.2024.54730
L1  - internal-pdf://3401314187/Crockett-2025-Interventions to Reduce Mental H.pdf
PY  - 2025
SP  - e2454730
T2  - JAMA Network Open
TI  - Interventions to Reduce Mental Health Stigma in Young People: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1001%2fjamanetworkopen.2024.54730
UR  - https://watermark.silverchair.com/crockett_2025_oi_241537_1736277617.93914.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAzMwggMvBgkqhkiG9w0BBwagggMgMIIDHAIBADCCAxUGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMrpzqb1aoEXNySP8hAgEQgIIC5ryPVBRRpgeTItAbgEkt4HDys2ZOVgcj2BJFf9i09E2GpTfG5l_Dw0TztC0efYp10ur30Iru6s6X4L1qzt32R4t-uA52jTI8SL77Ssi-7qVHpJQQyHUFzgigK2v6Xy_AxNCDsyImyv0Sdf2LWOv5Fwvweoxcc9bx9Lh4nD93YwNYV1PZ8gzVuTkSi6D-SIC5rpP43MrvAvbbtBpMTdvVANyuImG9LHOracgvaVa-lvWKxB4O41GqwEkUJcM15ls4dRc0-0KPyZ1kWCfpEZK4FrWPZAfCwwpeieKM6GyQmURrJvPQFVt_6mTbKfAH5N3MRkMwd8dOXRB3A74QazjzCUO070iN77DjY3wpQuYT6vbkND4MKX1BXBTP6Xlczt3YDO5FzApDguNzaDFxblsIJINeXfv3N73EZp7mKcu5oDTskDkIEksIJTy39q2MK0IU0_GNLHed0uDeMc6_c4snVKCWVsCV0doX51lgHbV4iW3ft78CoLRSHXy9sHa7h4vEZ5CnRA8ZC-rgbt9vhhvZSxwk0f_x5_WHC8qk1faDQHpENQvyw74qHfPL8VZCWamKbTpoWlXdeeG0W4NF0rSTI7roD45jliiby66qVuZ0y_qOkrlXaOsuwajDdEMGgb5dPtIEYKsSXaqSctoZl-8oWZnsNoqkniMnSfmNzXlt_ti75jysGg3JZ12jKtGYo61ePY1Y0e6yu54lceImIKfZPLwknPsIO-sd-4C_t58KicytEZtYSDJ5T4x2lKh_6JLb8LeaF4jq-morG8LoTFQxaL1hq4RxqA7BkYUirDyWPQae5VPlyDtHYxvXcryXxDNIBMuwTDXGdSNxlVoH7pCoUcJtqZmUcRDiWnme-c5-QX1BpyX683RFUNpGLAptzd93ylh55hOfAQ-0SSVuKxCcw6IPhkCzCLgd45gWjI_P0kOUbw8v1Z77CnX51RFPFpKjlh7j4q007BU4TKev52l9Ti457Pf8p_Y
VL  - 8
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Numerous studies have explored interventions to reduce digital addiction outcomes, but inconclusive evidence makes it difficult for decision-makers, managers, and clinicians to become familiar with all available literature and find appropriate interventions. **OBJECTIVE**: This study aims to summarize and assess the certainty of evidence of interventions proposed to decrease digital addiction from published meta-analyses. **METHODS**: An umbrella review of published meta-analyses was performed. We searched PubMed, Cochrane Library, Web of Science, and Embase for meta-analyses published up to February 2024. Eligible studies evaluated interventions using randomized controlled trials, nonrandomized controlled trials, or quasi-experimental studies and were assessed for methodological quality using Assessment of Multiple Systematic Reviews version 2. A random effects model was used to analyze data, considering heterogeneity and publication bias. Grading of Recommendations, Assessment, Development, and Evaluations was applied to assess evidence with certainty. **RESULTS**: A total of 5 studies assessing 21 associations were included in the umbrella review, of which 4 (80%) were high-quality meta-analyses. Weak evidence was observed in 19 associations, whereas null associations appeared in the remaining 2 associations. These associations pertained to 8 interventions (group counseling, integrated internet addiction [IA] prevention programs, psychosocial interventions, reality therapy, self-control training programs, cognitive behavioral therapy, interventions to reduce screen time in children, and exercise) and 9 outcomes (self-control, self-esteem, internet gaming disorder symptoms, time spent gaming, IA scores, screen use time, interpersonal sensitivity longlines, anxiety, and depression). Cognitive behavioral therapy reduces anxiety (standardized mean difference [SMD] 0.939, 95% CI 0.311 to 1.586), internet gaming disorder symptoms (SMD 1.394, 95% CI 0.664 to 2.214), time spent gaming (SMD 1.259, 95% CI, 0.311 to 2.206), and IA scores (SMD -2.097, 95% CI -2.814 to -1.381). Group counseling had a large effect on improving self-control (SMD 1.296, 95% CI 0.269 to 2.322) and reducing IA levels (SMD -1.417, 95% CI -1.836 to -0.997). Exercise intervention reduced IA scores (SMD -2.322, 95% CI -3.212 to -1.431), depression scores (SMD -1.421, 95% CI -2.046 to -797), and interpersonal sensitivity scores (SMD -1.433, 95% CI -2.239 to -0.627). **CONCLUSIONS**: The evidence indicates that current interventions to reduce digital addiction are weak. Data from more and better-designed studies with larger sample sizes are needed to establish robust evidence. **TRIAL REGISTRATION**: PROSPERO CRD42024528173; crd.york.ac.uk/PROSPERO/display_record.php?RecordID=528173.
AN  - 39933164
AU  - Lu,
AU  - P.
AU  - Qiu,
AU  - J.
AU  - Huang,
AU  - S.
AU  - Wang,
AU  - X.
AU  - Han,
AU  - S.
AU  - Zhu,
AU  - S.
AU  - Ning,
AU  - Y.
AU  - Zeng,
AU  - F.
AU  - F.
AU  - Yuan,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.2196/59656
L1  - internal-pdf://0338300121/jmir-2025-1-e59656.pdf
PY  - 2025
SP  - e59656
T2  - Journal of Medical Internet Research
TI  - Interventions for Digital Addiction: Umbrella Review of Meta-Analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.2196%2f59656
VL  - 27
ER  -
TY  - JOUR
AB  - This study provided a systematic review and meta-analysis of UCLA PEERS R for social skills improvement in adolescents or young adults with autism. A total of 21 randomized controlled trials and 10 non-randomized controlled trials were included, and six different outcome indicators were analyzed. The results showed that PEERS improved participants' knowledge of social skills, ability to apply social skills, and emotional intelligence, and the difference between caregiver-reported scores and teacher-reported scores was statistically significant. The PEERS intervention produced the smallest effect using PEERS in East Asia. This study discussed the significance of PEERS on the improvement of social skills in ASD and the reasons for the results of the subgroup analyses, and provided some recommendations for PEERS intervention methods that may help to improve the effectiveness of the intervention.
AN  - 40056598
AU  - Cheng,
AU  - Y.
AU  - Shi,
AU  - J.
AU  - Cheng,
AU  - X.
AU  - Wei,
AU  - Y.
AU  - Wang,
AU  - J.
AU  - Jiang,
AU  - Z.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.ajp.2025.104422
L1  - internal-pdf://3537328127/Cheng_2025.pdf
PY  - 2025
SP  - 104422
T2  - Asian Journal of Psychiatry
TI  - Impact of social knowledge and skills training based on UCLA PEERS R on social communication and interaction skills of adolescents or young adults with autism: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1016%2fj.ajp.2025.104422
UR  - https://www.sciencedirect.com/science/article/pii/S1876201825000656?via%3Dihub
VL  - 106
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Targeted interventions are needed to prevent depression in at-risk children and adolescents. Children and adolescents are commonly at risk of depression due to subsyndromal depressive symptoms or problems in their social environment. **METHODS**: This review was conducted according to the Cochrane guidelines (2023) and reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. A literature search was done in December 2023 using three electronic databases and a manual search. The methodological quality of all eligible studies was assessed using the Cochrane Collaboration's tool for assessing the risk of bias. **RESULTS**: This review includes 77 intervention studies of which 13 are follow-ups. Of the 64 identified main studies (n = 11,808), 19 were selective interventions targeting the problems in a social environment. Of the participants 63.6 % were girls and the mean age ranged between 9 and 17. Most of the studies were conducted in a Western school setting using psychological interventions, with the majority being CBT (cognitive behavioral therapy) based programs. Targeted interventions reduced the symptoms of depression statistically significantly at postintervention (SMD 0.27, 95 % confidence interval 0.16-0.37) and 6-month follow-up (SMD 0.32, 0.18-0.45) compared to any comparator. Intervention effects were not statistically significant at the 12-month follow-up. **CONCLUSION**: Indicated and selective interventions targeted to children and adolescents at risk of depression due to their social environment have a small effect on depressive symptoms. Interventions should be delivered by mental health experts.
AN  - 39914750
AU  - Luttinen,
AU  - J.
AU  - Watroba,
AU  - A.
AU  - Niemela,
AU  - M.
AU  - Miettunen,
AU  - J.
AU  - Ruotsalainen,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.jad.2025.02.002
L1  - internal-pdf://3433563636/1-s2.0-S0165032725001892-main.pdf
PY  - 2025
SP  - 189-205
T2  - Journal of Affective Disorders
TI  - The effectiveness of targeted preventive interventions for depression symptoms in children and adolescents: Systematic review and meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1016%2fj.jad.2025.02.002
UR  - https://www.sciencedirect.com/science/article/pii/S0165032725001892?via%3Dihub
VL  - 376
ER  -
TY  - JOUR
AB  - Parenting programs worldwide provide families with essential knowledge and skills to foster positive child development. Meta-analyses on the effectiveness of parenting programs for parent and child outcomes predominantly included families from so-called WEIRD (Western, Educated, Industrialized, Democratic) countries. Expanding upon existing meta-analyses, the current study focused solely on Middle East/North Africa (MENA) countries through a systematic search of the literature for records that evaluated the effectiveness of parenting programs delivered during early childhood (birth to eight years). A total of 395 effect sizes of parent outcomes and 190 effect sizes of child outcomes were obtained from 29 studies. Using multilevel meta-analytic models, the pooled effects suggested that parenting programs had a positive effect on parent (g =1.01) and child outcomes (g = 1.43). An examination of publication bias suggested that the effects were robust. Moderator analyses showed trends suggesting that the overall effect may be influenced by program, study, and sample characteristics. Greater improvement of parent outcomes was not associated with greater improvement of child outcomes. Together, parenting programs may be promising support services for parents in MENA countries, with the potential of enhancing parenting and promoting psychosocial health and well-being for parents and children. Further implementation research is needed in MENA countries to increase knowledge about mechanisms and processes underlying effective parenting programs.
AN  - WOS:001357467400001
AU  - von
AU  - Suchodoletz,
AU  - A.
AU  - Camia,
AU  - C.
AU  - Maliki,
AU  - A.
AU  - Alwahedi,
AU  - M.
AU  - S.
AU  - Kelly,
AU  - M.
AU  - P.
DB  - November 2024.enl
DO  - 10.1016/j.ecresq.2024.10.013
L1  - internal-pdf://2878176983/1-s2.0-S0885200624001492-main.cleaned.pdf
PY  - 2025
SP  - 334-346
T2  - Early Childhood Research Quarterly
TI  - Parenting programs in the Middle East/North Africa (MENA) region: A multilevel meta-analysis
UR  - <Go to ISI>://WOS:001357467400001
UR  - https://www.sciencedirect.com/science/article/pii/S0885200624001492?pes=vor&utm_source=clarivate&getft_integrator=clarivate
VL  - 70
ER  -
TY  - JOUR
AB  - **Background** Asthma is a chronic airway condition with a global prevalence of 262.4 million people. Asthma education is an essential component of management and includes provision of information on the disease process and self‐management skills development such as trigger avoidance. Education may be provided in various settings. The home setting allows educators to reach populations (e.g. financially poor) that may experience barriers to care (e.g. transport limitations) within a familiar environment, and allows for avoidance of attendance at healthcare settings. However, it is unknown if education delivered in the home is superior to usual care or the same education delivered elsewhere. There are large variations in asthma education programmes (e.g. patient‐specific content versus broad asthma education, number/frequency/duration of education sessions). This is an update of the 2011 review with 14 new studies added. Objectives To assess the effects of educational interventions for asthma, delivered in the home to children, their caregivers, or both, on asthma‐related outcomes. **Search methods**: We searched Cochrane Airways Group Trials Register, CENTRAL, MEDLINE, two additional databases and two clinical trials registries. We searched reference lists of included trials/review articles (last search October 2022), and contacted authors of included studies. Selection criteria We included randomised controlled trials of education delivered in the home to children and adolescents (aged two to 18 years) with asthma, their caregivers or both. We included self‐management programmes, delivered face‐to‐face and aimed at changing behaviour (e.g. medication/inhaler technique education). Eligible control groups were usual care, waiting list or less‐intensive education (e.g. shorter, fewer sessions) delivered outside or within the home. We excluded studies with mixed‐disease populations and without a face‐to‐face component (e.g. telephone only). **Data collection and analysis**: Two review authors independently selected trials, assessed trial quality, extracted data and used GRADE to rate the certainty of the evidence. We contacted study authors for additional information. We pooled continuous data with mean difference (MD) and 95% confidence intervals (CI). We used a random‐effects model and performed sensitivity analyses with a fixed‐effect model. When combining dichotomous and continuous data, we used generic inverse variance, using a Peto odds ratio (OR) and fixed‐effect model. Primary outcomes were exacerbations leading to emergency department visits and exacerbations requiring a course of oral corticosteroids. Six months was the primary time point for outcomes. The summary of findings tables reported on the primary outcomes, and quality of life, daytime symptoms, days missed from school and exacerbations leading to hospitalisations. Main results This review includes 26 studies with 5122 participants (14 studies and 2761 participants new to this update). Sixteen studies (3668 participants) were included in meta‐analyses. There was substantial clinical diversity. Participants differed in age (range 1 to 18 years old) and asthma severity (mild to severe). The context and content of educational interventions also varied, as did the aims of the studies (e.g. reducing healthcare utilisation, improving quality of life) and there was diversity in control group event rates. Outcomes were measured over various time points specified in the original studies. All studies were at risk of bias due to the nature of the intervention. It is possible that the participants/educators may not have been aware of their allocation, so all studies were judged at unclear risk for performance bias. Home‐based education versus usual care, waiting list or less‐intensive education programme delivered outside the home Primary outcomes Home‐based education may result in little to no difference in exacerbations leading to emergency department visits at six‐month follow‐up compared to control, but the evidence is very uncertain (Peto OR 1.22, 95% CI 0.50 to 2.94; 5 studies (2 studies with 2 intervention arms), 855 participants; very low‐certainty evidence). Home‐based education results in little to no difference in exacerbations requiring a course of oral corticosteroids compared to control (mean difference (MD) −0.18, 95% CI −0.63 to 0.26; 1 study (2 intervention arms), 250 participants; low‐certainty evidence). Secondary outcomes Home‐based education may improve quality‐of‐life scores compared to control, but the evidence is very uncertain (standardised mean difference (SMD) 0.32, 95% CI 0.08 to 0.56; 4 studies, 987 participants; very low‐certainty evidence). The evidence is very uncertain about the effects of home‐based education on mean symptom‐free days, days missed from school/work and exacerbations leading to hospitalisation compared to control (all very low‐certainty evidence). Home‐based education versus less‐intensive home‐based education for children with asthma Primary outcomes A more‐intensive home‐based education intervention did not reduce exacerbations leading to emergency department visits (Peto OR 1.36, 95% CI 0.35 to 5.30; 4 studies, 729 participants; low‐certainty evidence) or exacerbations requiring a course of oral corticosteroids (MD 0.08, 95% CI −0.14 to 0.30; 3 studies, 605 participants; low‐certainty evidence), compared to a less‐intensive type of home‐based education. Secondary outcomes A more‐intensive home‐based asthma education intervention may reduce hospitalisation due to an asthma exacerbation (Peto OR 0.14, 95% CI 0.04 to 0.55; 4 studies, 689 participants; low‐certainty evidence), but not days missed from school (low‐certainty evidence), compared with a less‐intensive home‐based asthma education intervention. A more intensive home‐based education intervention had no effect on quality of life and symptom‐free days (both very low certainty), compared with a less‐intensive home‐based asthma education intervention, but the evidence is very uncertain. Authors' conclusions We found uncertain evidence for home‐based asthma educational interventions compared to usual care, education delivered outside the home or a less‐intensive educational intervention. Home‐based education may improve quality of life compared to control and reduce the odds of hospitalisation compared to less‐intensive educational intervention. Although asthma education is recommended in guidelines, the considerable diversity in the studies makes the evidence difficult to interpret about whether home‐based education is superior to none, or education delivered in another setting. This review contributes limited information on the fundamental optimum content and setting for educational interventions in children. Further studies should use standard outcomes from this review and design trials to determine what components of an education programme are most important. Plain language summary How useful is it to deliver asthma education to children, or their caregivers, or both, in the home? Key messages – There is limited evidence that home‐based education improves quality of life compared with education delivered out of the home, and reduces admissions to hospital compared with a less‐intensive education. – There is not enough evidence to show whether education delivered in the home is better or worse than education delivered outside the home for exacerbations (worsening of asthma) requiring an emergency department visit, treatment with oral corticosteroids (medicine used to treat asthma that reduces inflammation (swelling) in the airways), changes in asthma symptoms or how well the lungs work. – Well‐designed trials are needed to address the exact components of asthma education that are linked with improved asthma knowledge and outcomes. What is asthma? Asthma is a chronic (long term) lung condition. People with asthma have inflammation (swelling) in the airways in the lungs. The symptoms are wheeze, shortness of breath, chest tightness and cough. What is asthm education? Asthma education aims to teach children and caregivers how to manage their asthma using a partnership between the patient and healthcare professionals. Components of asthma education include information about asthma; training in managing asthma, including how to use inhalers effectively; a management strategy; and encouragement to use medications correctly. Monitoring of asthma, such as with a peak flow meter (a hand‐held device that measures how quickly you can breathe out fully) and regular healthcare professional reviews are also components of asthma education. Why do we think the home might be a good place to give children asthma education? The home setting allows educators to reach populations (such as those with poorer backgrounds) that may experience barriers to care (such as lack of transportation) within a familiar environment, and prevents a need for attendance at healthcare settings. This review update is timely because following the COVID‐19 pandemic, healthcare policymakers are thinking more broadly about how and where care is delivered. What did we want to find out? While guidelines recommend that children with asthma should receive asthma education, it is not known if education delivered in the home is superior to usual care (no education or education delivered elsewhere). We wanted to consider if the intensity of the education (e.g. how many education sessions were given) had any impact on children with asthma. What did we do? We searched for studies delivering home‐based education about asthma to children or their caregivers. The education had to be compared to control (either no education or education delivered at a healthcare centre), or to a less‐intensive education delivered at home. We compared and summarised the results of the studies and rated our confidence in the evidence, based on factors such as study methods and sizes. What did we find? We found 26 studies involving 5122 children. Most studies were done in North America. Most families were from poorer areas. Children differed in terms of age, severity of asthma and type of educational intervention. **Results**: We found that home‐based education may result in little to no difference in exacerbations leading to emergency department visits, but the evidence is very uncertain. We found that there may be little or no difference in the number of courses of oral corticosteroids prescribed (a medicine used to treat asthma that reduces inflammation (swelling) in the airways). We found there may be some improvement in quality of life with home‐based education compared to control, and reduced admissions to hospital with an asthma exacerbation compared to less‐intensive education, but the evidence is uncertain. Asthma symptom‐free days and days missed from school or work also showed considerable uncertainty when compared with either control or less‐intensive education, and there may be little or no difference in these outcomes. What are the limitations of the evidence? The children and families may have known which treatment they received. There were many differences between the children's asthma severity, the types of education delivered and other factors. There were also many differences between the control groups of the included studies (that is, who the education group was compared to). This makes it difficult to know whether treatments had any impact on children with asthma because the studies were so different. The aims of a treatment might be different too. For some children whose families have little asthma knowledge, the aim may have been to improve their knowledge of symptoms. This may encourage them to go to the emergency department more often. However, for some children who have poorly controlled asthma and may be going to the emergency department a lot, the aim may have been to decrease the number of emergency department visits. This might be by teaching them how to use their medications properly so they have improved asthma control. This makes thinking about the evidence more complicated. How up to date is this evi ence? This is the first update of a Cochrane review first published in 2011. The information is current to October 2022.
AN  - CD008469
AU  - O'Connor,
AU  - A.
AU  - Hasan,
AU  - M.
AU  - Sriram,
AU  - K.
AU  - B.
AU  - Carson-Chahhoud,
AU  - K.
AU  - V.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - 10.1002/14651858.CD008469.pub3
KW  - *Asthma [therapy]
KW  - *Caregivers [education]
KW  - *Patient Education as Topic [methods]
KW  - *Quality of Life
KW  - *Randomized Controlled Trials as Topic
KW  - Adolescent
KW  - Anti-Asthmatic Agents [therapeutic use]
KW  - Child
KW  - Child, Preschool
KW  - Home Care Services
KW  - Humans
KW  - Self Care
KW  - Self-Management [education]
L1  - internal-pdf://0658593822/O'Connor_et_al-2025-Cochrane_Database_of_Syste.pdf
N1  - [Central Editorial Service]
PY  - 2025
T2  - Cochrane Database of Systematic Reviews
TI  - Home‐based educational interventions for children with asthma
UR  - https://doi.org//10.1002/14651858.CD008469.pub3
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Perinatal depression and anxiety are the most common mental health disorders among pregnant and postpartum adolescents. Pharmacological and non-pharmacological interventions exist for perinatal depression and anxiety; however, there is limited evidence on the effectiveness of non-pharmacological interventions in adolescent mothers. **AIM**: To identify, evaluate, and summarize the available evidence on the effectiveness of non-pharmacological interventions for the prevention and treatment of perinatal depression and anxiety in adolescent mothers. **METHODS**: We followed the Cochrane guidelines in conducting the reviews and the Preferred Reporting Items for Systematic review and Meta-Analysis (PRISMA) guidelines in reporting the findings. Randomized clinical trials (RCTs), interventional studies, cohort studies, and case-control studies of non-pharmacological interventions that assessed depression and/or anxiety symptoms or diagnoses after intervention in adolescent mothers were eligible for inclusion. We searched PubMed/Medline, Embase, Cochrane Central Register of Controlled Trials, and PsycINFO, as well as the reference lists of relevant studies and grey literature. **RESULTS**: We identified eight clinical trials that were eligible for inclusion in the systematic review (n=806); four of these studies were eligible for inclusion in a meta-analysis (n=451). Non-pharmacological interventions (specifically Cognitive Behavioral Therapy (CBT) and Interpersonal Therapy (IPT)) for depressive symptoms showed small to moderate effects (SMD: -0.57, 95% CI: -0.77, -0.36; p-value<0.001) in the intervention groups compared to the control groups. **CONCLUSIONS**: Non-pharmacological interventions, specifically CBT and IPT, may be effective in treating perinatal depression among adolescent mothers. These interventions could be successfully delivered by trained health care professionals in health care settings such as antenatal clinics.
AN  - 40081580
AU  - Mwita,
AU  - M.
AU  - Dewey,
AU  - D.
AU  - Konje,
AU  - E.
AU  - T.
AU  - Patten,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.jad.2025.03.056
L1  - internal-pdf://2260949131/1-s2.0-S0165032725003945-main.pdf
PY  - 2025
SP  - 11
T2  - Journal of Affective Disorders
TI  - Non-pharmacological interventions for perinatal depression and anxiety among adolescent mothers: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.jad.2025.03.056
UR  - https://www.sciencedirect.com/science/article/pii/S0165032725003945?via%3Dihub
VL  - 11
ER  -
TY  - JOUR
AB  - **Introduction**: The effects of cognitive remediation therapy (CRT) in adults with mental health disorders have been widely documented, but its effects in adolescents with mental health disorders remain poorly understood. This review aims to (1) determine the effects of CRT on cognition, symptoms and functioning for adolescents with mental health disorders and (2) evaluate the methodological quality of studies on CRT.*Methods**: A systematic review and meta-analysis were conducted of randomised controlled trials of CRT involving adolescents with mental health disorders. Searches were conducted in databases for studies pertaining to CRT effects on cognition, social functioning and clinical symptoms. Methodological quality was assessed using the Clinical Trials Assessment Measure.**Results**: Fourteen studies (N = 14) were included, with 11 independent samples (k = 11, 592 participants). Participants had various mental health disorders. CRT showed a small significant effect on cognition (g = 0.14, p = 0.02), particularly on processing speed, working memory and episodic memory. No significant effects were found for clinical symptoms (g = 0.04, p = 0.58) and social functioning (g = 0.06, p = 0.39). Methodological quality of included studies was variable, ranging from poor to good quality. **Conclusion**: Included studies showed a small significant effect of CRT on cognition, and non-significant effects on clinical symptoms and social functioning in adolescents with mental health disorders. The lack of effects may be partly explained by limitations in the methodology of included studies. A critical analysis of current studies is presented and recommendations of core techniques to consider for future CRT studies are discussed.
AN  - WOS:001418066300001
AU  - East-Richard,
AU  - C.
AU  - Cayouette,
AU  - A.
AU  - Allott,
AU  - K.
AU  - Anderson,
AU  - E.
AU  - Haesebaert,
AU  - F.
AU  - Cella,
AU  - M.
AU  - Cellard,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1111/eip.70016
L1  - internal-pdf://2157571544/East-Richard-2025-Cognitive Remediation for Ad.pdf
PY  - 2025
SP  - 19
T2  - Early Intervention in Psychiatry
TI  - Cognitive Remediation for Adolescents With Mental Health Disorders: A Systematic Review and Meta-Analysis
UR  - <Go to ISI>://WOS:001418066300001
VL  - 19
ER  -
TY  - JOUR
AB  - **Background**: Pediatric patients undergoing surgery frequently experience significant anxiety, which can result in adverse effects such as prolonged sedation and behavioral changes associated with pharmacological interventions such as oral midazolam. Video games offer a nonpharmacological distraction method that shows promise in alleviating procedural anxiety without significant adverse effects. However, the effectiveness of video games compared to midazolam in managing perioperative anxiety remains uncertain. **Objective**: This study aimed to evaluate the effectiveness of video game interventions in reducing perioperative anxiety in pediatric patients undergoing general anesthesia. **Methods**: We conducted a comprehensive search across PubMed, Embase, Web of Science, and the Cochrane Library, supplemented by reference screening. Primary outcomes included anxiety levels assessed during parent separation and mask induction procedures, while secondary outcomes encompassed emergence delirium, postoperative behavior, and length of stay in the postanesthesia care unit (PACU). The risk of bias was assessed using the Risk of Bias 2 scale. Data were synthesized descriptively and through meta-analysis, with the certainty of the evidence evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria. **Results**: Six randomized controlled trials involving 612 participants were included in the analysis. Children who participated in video game interventions reported significantly lower anxiety levels during parent separation (standardized mean difference, SMD -0.31, 95% CI -0.50 to -0.12; P=.001), with high certainty, and during mask induction (SMD -0.29, 95% CI -0.52 to -0.05; P=.02), with moderate certainty, compared to those receiving oral midazolam. Additionally, significant differences in postoperative behavior changes in children were observed compared to oral midazolam (SMD -0.35, 95% CI -0.62 to -0.09; P=.008). Children in the video game intervention groups also had a shorter length of stay in the PACU (mean difference, MD -19.43 min, 95% CI -31.71 to -7.16; P=.002). However, no significant differences were found in emergence delirium (MD -2.01, 95% CI -4.62 to 0.59; P=.13). **Conclusions**: Video game interventions were more effective than midazolam in reducing perioperative anxiety among pediatric patients, improving postoperative behavior, and shortening the length of stay in the PACU. However, video games alone did not outperform midazolam in managing emergence delirium. Further high-quality research is needed for more conclusive results.
AN  - 40063979
AU  - Luo,
AU  - Z.
AU  - Deng,
AU  - S.
AU  - Zhou,
AU  - R.
AU  - Ye,
AU  - L.
AU  - Zhu,
AU  - T.
AU  - Chen,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.2196/67007
L1  - internal-pdf://0485447804/games-2025-1-e67007.pdf
PY  - 2025
SP  - e67007
T2  - JMIR Serious Games
TI  - Comparative Efficacy of Video Games Versus Midazolam in Reducing Perioperative Anxiety in Pediatric Patients: Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.2196%2f67007
VL  - 13
ER  -
TY  - JOUR
AB  - This review analyzes randomized controlled studies that investigated parent training interventions in Europe. Included studies had to have utilized interventions based on social learning theory and enrolled immigrant families. Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were followed, and the review was pre-registered with PROSPERO. A search of nine databases identified 8286 publications, seven of which fulfilled the inclusion criteria. These articles were published between 2010 and 2017. Since 1996, extremely few effective trials have been conducted in Europe. The meta-analysis revealed a small but significant overall effect for child problem behaviors and positive and negative parenting (effect size = 0.26, 0.24, and 0.20, respectively), compared with the control conditions, thus favoring parent training. Only some studies have addressed the migration or cultural issues in family life-a barrier to the development of future programs. This review highlights issues such as cultural adaptation and intersectionality to assist evaluators and planners in improving the practice of their professions and their knowledge base. We call for more evidence regarding the effects of parental programs on immigrant families living in Europe.
AN  - 39986021
AU  - Bjorknes,
AU  - R.
AU  - Saus,
AU  - M.
AU  - Neumer,
AU  - S.
AU  - P.
AU  - Gammelsaeter,
AU  - S.
AU  - Halvorsen,
AU  - T.
AU  - B.
AU  - Patras,
AU  - J.
AU  - Douglas,
AU  - M.
AU  - Haug,
AU  - I.
AU  - M.
AU  - Rasmussen,
AU  - L.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.evalprogplan.2025.102555
L1  - internal-pdf://0489379917/Bjørknes_2025.pdf
PY  - 2025
SP  - 102555
T2  - Evaluation & Program Planning
TI  - Parent training programs for immigrant families in Europe: A systematic review and meta-analysis of randomized trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1016%2fj.evalprogplan.2025.102555
UR  - https://www.sciencedirect.com/science/article/pii/S0149718925000229?via%3Dihub
VL  - 110
ER  -
TY  - JOUR
AB  - Suicide and self-harm are a leading cause of death globally, with females aged 15-24 years being a high-risk group requiring urgent intervention. Promoting mental health literacy is a well-established strategy for early intervention. No review has explored the available interventions promoting mental health literacy for female adolescents and their reach, effectiveness, adoption, implementation, and maintenance as a whole remains unknown. This study reviews existing interventions promoting mental health literacy in female adolescents. Searches included original peer-reviewed articles from inception to May 2024 across six databases, identifying twelve studies for review. Five independent meta-analyses were conducted, showing no significant effects immediately post-intervention for mental health literacy, knowledge, stigmatising attitudes, and help-provision. A significant reduction in stigmatising attitudes was found > 6 months post-intervention. Moderation analyses could not be performed due to insufficient data. None of the included studies reported on interventions specifically for female adolescents. This review also evaluated reporting of RE-AIM components, finding limited reporting on reach, adoption, and maintenance. These findings highlight a substantial gap in high-impact and tailored mental health prevention and promotion interventions for female adolescents. Therefore, there is a clear need to understand and target female adolescents' mental health literacy needs to develop and implement more effective interventions.
AN  - 39841249
AU  - Arnold,
AU  - E.
AU  - R.
AU  - Liddelow,
AU  - C.
AU  - Lim,
AU  - A.
AU  - S.
AU  - X.
AU  - Vella,
AU  - S.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1007/s00787-025-02648-2
L1  - internal-pdf://1854004789/Arnold-2025-Mental health literacy interventio.pdf
PY  - 2025
SP  - 22
T2  - European Child & Adolescent Psychiatry
TI  - Mental health literacy interventions for female adolescents: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs00787-025-02648-2
UR  - https://link.springer.com/content/pdf/10.1007/s00787-025-02648-2.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - **OBJECTIVES**: To evaluatethe effectiveness of social skills training (SST) interventions for children with autism spectrum disorder (ASD). **METHODS**: A systematic review and meta-analysis were carried out to identify relevant studies published between 2000-2023. The study was conducted in accordance with the PRISMA guidelines. Studies were included if they met the following criteria: randomized controlled trials (RCTs) or quasi-RCTs, participants were children with ASD aged 3-18 years, SST interventions were delivered individually or in groups, and social skills were assessed using standardized measures. Effect sizes were calculated using Cohen's d, and meta-analyses were carried out using a random-effects model. **RESULTS**: A total of 17 studies were included in the meta-analysis. The overall effect size for SST interventions was 0.28-0.60 (95% confidence interval: [0.23-0.41]), indicating a small to moderate effect. Social skills training interventions were effective in improving a range of social skills, including social communication, reciprocity, and joint attention. **CONCLUSION**: Social skills training interventions demonstrate modest to moderate effectiveness in improving social skills in children with ASD, with outcomes varying depending on intervention type, participant characteristics, and implementation fidelity. While SST interventions offer potential benefits, they should be considered as one component of a broader, individualized treatment plan for children with ASD, rather than a standalone solution. **PROSPERO No. ID: CRD42024578682**.
AN  - 40096975
AU  - Alahmari,
AU  - F.
AU  - S.
AU  - Alhabbad,
AU  - A.
AU  - A.
AU  - Alshamrani,
AU  - H.
AU  - A.
AU  - Almuqbil,
AU  - M.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.15537/smj.2025.46.3.20240788
L1  - internal-pdf://2269337770/Alahmari-2025-Effectiveness of social skills t.pdf
PY  - 2025
SP  - 226-237
T2  - Saudi Medical Journal
TI  - Effectiveness of social skills training interventions for children with autism spectrum disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.15537%2fsmj.2025.46.3.20240788
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11918677/pdf/smj-46-3-226.pdf
VL  - 46
ER  -
TY  - JOUR
AB  - Negative self-perceptions are implicated in the development and maintenance of depression in young people, but little is known about their receptiveness to change in response to treatment. This paper reports on a pre-registered meta-analysis examining the extent to which treatments for depression in young people aged 11-24 result in changes to self-perceptions. Controlled treatment trials examining outcomes related to self-perceptions were synthesised (k = 20, N = 2041), finding small reductions in both symptoms of depression (g = -0.30; 95 % CI: -0.52, -0.08) and self-perception outcomes (g = 0.33; 95 % CI: 0.16, 0.49) for interventions compared with control groups. Meta-regression analyses found no significant association between reductions in depressive symptoms and improvements in self-perception following treatment, suggesting that despite interventions generally improving both outcomes these changes may be unrelated to each other. Our results indicate that young people's self-perceptions are sensitive to change following treatment for depression, however effect sizes are small and treatments could be more effective in targeting and changing negative self-perceptions. Given the importance that young people place on integrating work on their sense of self into treatments for depression, future interventions could aim to support young people with depression to develop a positive sense of self.
AN  - 39622116
AU  - Dean,
AU  - R.
AU  - L.
AU  - Lester,
AU  - K.
AU  - J.
AU  - Grant,
AU  - E.
AU  - Field,
AU  - A.
AU  - P.
AU  - Orchard,
AU  - F.
AU  - Pile,
AU  - V.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.cpr.2024.102521
L1  - internal-pdf://2114384645/6c9a5062-93b4-4b83-a2fd-620dc6b68d08.pdf
PY  - 2025
SP  - 102521
T2  - Clinical Psychology Review
TI  - The impact of interventions for depression on self-perceptions in young people: A systematic review & meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1016%2fj.cpr.2024.102521
UR  - https://www.sciencedirect.com/science/article/pii/S0272735824001429?via%3Dihub
VL  - 115
ER  -
TY  - JOUR
AB  - **Objective**: Mindfulness-based interventions are increasingly being used in schools to improve students' mental, emotional, and behavioral development. Although many mindfulness programs exist, the types of programs that are effective for specific age groups remain unclear. In this systematic review, the authors used established rating criteria to describe the level of evidence for school-based mindfulness interventions. **Methods**: A search of major databases, gray literature, and evidence base registries was conducted to identify studies published between 2008 and 2022 that focused on mindfulness interventions within school settings. The authors rated mindfulness interventions as having high, moderate, or low levels of evidence based on the number and rigor of studies with positive outcomes. **Results**: Of the 24 interventions identified across 41 studies, three interventions-Learning to BREATHE, Mindfulness in School Project, and mindfulness-based stress reduction (MBSR)-received a rating of high level of evidence. Three interventions-Gaia Program, MindUP, and a blended version of MBSR and mindfulness-based cognitive therapy-received a rating of moderate level of evidence. The interventions rated as having a high level of evidence were conducted with middle or high school students, and interventions with moderate evidence were also conducted with elementary students, demonstrating effectiveness of mindfulness across a range of age groups. Few studies examined outcomes for underserved populations. **Conclusions**: With greater use and more research, mindfulness interventions have the potential to promote student well-being and prevent mental health conditions.
AN  - WOS:001390726000007
AU  - Marshall,
AU  - T.
AU  - Farrar,
AU  - A.
AU  - Wilson,
AU  - M.
AU  - Taylor,
AU  - J.
AU  - George,
AU  - P.
AU  - Ghose,
AU  - S.
AU  - S.
AU  - Cosgrove,
AU  - J.
AU  - Patel,
AU  - N.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1176/appi.ps.20240027
L1  - internal-pdf://3509461383/6c68cd45-5e86-43d3-ab37-0fdf55bd0d9c.pdf
PY  - 2025
SP  - 49-60
T2  - Psychiatric Services
TI  - Mindfulness-Based Interventions in Schools: Assessing the Evidence Base
UR  - <Go to ISI>://WOS:001390726000007
VL  - 76
ER  -
TY  - JOUR
AB  - **BACKGROUND** Extended reality (XR) technologies are increasingly being used to reduce health and procedural anxieties. The global effectiveness of these interventions is uncertain, and there is a lack of understanding of how patient outcomes might vary between different contexts and modalities. **OBJECTIVE** This research used panoramic meta-analysis to synthesize evidence across the diverse clinical contexts in which XR is used to address common outcomes of health and procedural anxiety. **METHODS** Review-level evidence was obtained from 4 databases (MEDLINE, Embase, APA PsycINFO, and Epistemonikos) from the beginning of 2013 until May 30, 2023. Reviews that performed meta-analysis of randomized controlled trials relating to patient-directed XR interventions for health and procedural anxiety were included. Studies that analyzed physiological measures, or focused on technologies that did not include meaningful immersive components, were excluded. Furthermore, data were only included from studies that compared intervention outcomes against no-treatment or treatment-as-usual controls. Analyses followed a preregistered, publicly available protocol. Trial effect sizes were extracted from reviews and expressed as standardized mean differences, which were entered into a 3-level generalized linear model. Here, outcomes were estimated for patients (level 1), studies (level 2), and anxiety indications (level 3), while meta-regressions explored possible influences of age, immersion, and different mechanisms of action. Where relevant, the quality of reviews was appraised using the AMSTAR-2 (A Measurement Tool to Assess Systematic Reviews, Revised Instrument) tool. **RESULTS** Data from 83 individual trials were extracted from 18 eligible meta-analyses. Most studies involved pediatric patient groups and focused on procedural, as opposed to general, health anxieties (eg, relating to needle insertion, dental operations, and acute surgery contexts). Interventions targeted distraction-, education-, and exposure-based mechanisms, and were provided via a range of immersive and nonimmersive systems. These interventions proved broadly effective in reducing patient anxiety, with models revealing significant but heterogeneous effects for both procedural (d=-0.75, 95% CI -0.95 to -0.54) and general health (d=-0.82, 95% CI -1.20 to -0.45) indications (when compared with nontreatment or usual-care control conditions). For procedural anxieties, effects may be influenced by publication bias and appear more pronounced for children (vs adults) and nonimmersive (vs immersive) technology interventions, but they were not different by indication. **CONCLUSIONS** Results demonstrate that XR interventions have successfully reduced patient anxiety across diverse clinical contexts. However, significant uncertainty remains about the generalizability of effects within various unexplored indications, and existing evidence is limited in methodological quality. Although current research is broadly positive in this area, it is premature to assert that XR interventions are effective for any given health or procedural anxiety indication.
AN  - 39778203
AU  - Arthur,
AU  - T.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Harris,
AU  - D.
AU  - Robinson,
AU  - S.
AU  - Wilson,
AU  - M.
AU  - Vine,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.2196/58086
L1  - internal-pdf://0554557419/a10f48a0-731f-45db-a5a0-ca649afa22bb.pdf
PY  - 2025
SP  - e58086
T2  - Journal of Medical Internet Research
TI  - Extended Reality Interventions for Health and Procedural Anxiety: Panoramic Meta-Analysis Based on Overviews of Reviews
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.2196%2f58086
VL  - 27
ER  -
TY  - JOUR
AB  - **OBJECTIVES**: The current study aimed at investigating the efficacies of probiotics in alleviating the symptoms of irritability/emotional lability in individuals with a neurodevelopmental condition. **METHODS**: Randomized placebo-controlled trials were identified through searching major electronic databases from inception to December, 2023. The outcome of interests included improvements in the symptoms of irritability/emotional lability. Outcomes were quantitatively expressed as effect size (ES) based on standardized mean difference (SMD) with 95% confidence interval (CI). **RESULTS**: Seven studies with 1479 participants were included in this meta-analysis. The primary results revealed a significant improvement in the symptoms of irritability/emotional lability in individuals with neurodevelopmental conditions receiving probiotics compared with the placebos (SMD= -0.17, p=0.03). Subgroup analyses demonstrated an association between a significant improvement in the symptoms of irritability/emotional lability and the use probiotics relative to placebos only in studies using multiple-strain probiotics (SMD=-0.19, p=0.04, three studies with 452 participant) but not in those adopting single-strain regimens. **CONCLUSIONS**: Our study supported the use of probiotics for alleviating the symptoms of irritability/emotional lability in individuals with neurodevelopmental conditions, mainly in those receiving multiple-strain probiotics as supplements. Nevertheless, the limited number of studies targeting irritability as their primary outcomes, and most did not investigate other confounding factors such as dietary habits or consumption of other nutritional supplements may impair the robustness of evidence. Our results, which were derived from a limited number of available trials, warrant further large-scale clinical investigations for verification.
AN  - 39864755
AU  - Huang,
AU  - P.
AU  - W.
AU  - Chia-Min,
AU  - C.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Tang,
AU  - Y.
AU  - H.
AU  - Liu,
AU  - C.
AU  - Hung,
AU  - K.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.ctim.2025.103132
L1  - internal-pdf://3938058855/1f56de4e-1fd3-429b-a1f5-45d93ece1eb0.pdf
PY  - 2025
SP  - 103132
T2  - Complementary Therapies in Medicine
TI  - Therapeutic effects of probiotics on symptoms of irritability/emotional lability associated with neurodevelopmental conditions: A systematic review and meta-analysis of placebo-controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.ctim.2025.103132
UR  - https://www.sciencedirect.com/science/article/pii/S096522992500007X?via%3Dihub
VL  - 89
ER  -
TY  - JOUR
AB  - **INTRODUCTION**: Preterm and low birth weight (LBW) infants are at an increased risk of morbidity and mortality compared with their term counterparts, with more than 20 million LBW infants born each year, the majority in lower middle-income countries (LMICs). Given the increased vulnerability and higher nutritional needs of these infants, optimizing feeding strategies may play a crucial role in improving their health outcomes. **METHODS**: We updated evidence of Every Newborn Series published in The Lancet 2014 by identifying relevant systematic reviews, extracting low-income country (LIC) and LMIC data, and conducting revised meta-analysis for these contexts. **RESULTS**: We found 15 reviews; the evidence showed that early initiation of enteral feeding reduced neonatal mortality overall, but not in LIC/LMIC settings. Breastfeeding promotion interventions increased the prevalence of early initiation of breastfeeding and exclusive breastfeeding at 3 and 6 months of age in LMIC settings. There was an increased risk of neonatal mortality with formula milk in LIC/LMIC settings. Despite contributing to greater weight gain, there was a higher risk of necrotizing enterocolitis with formula milk overall. Breast milk fortification and nutrient-enriched formula improved growth outcomes. Iron and vitamin A supplementation reduced anemia and mortality rates (LMIC), respectively. The evidence also suggested that benefits of various different micronutrient supplementation interventions such as zinc, calcium/phosphorous, and vitamin D, outweigh the risks since our review demonstrates little to no adverse effects deriving from their supplementation, particularly for a breastfed preterm and/or LBW infant. **CONCLUSION**: Early adequate nutritional support of preterm or LBW infant is paramount to averse adverse health outcomes, contribute to normal growth, resistance to infection, and optimal development. Breast milk feeding and micronutrient supplementation are crucial to reduce diarrhea incidence and mortality respectively while feed fortification or nutrient-enriched formula, when breast milk is not available, to enhance better growth especially in LMICs where there is higher population of growth restriction and stunting. This review also highlights need for randomized trials in LMICs at large scale to further strengthen the evidence.
AN  - 39591949
AU  - Azhar,
AU  - M.
AU  - Yasin,
AU  - R.
AU  - Hanif,
AU  - S.
AU  - Bughio,
AU  - S.
AU  - A.
AU  - Das,
AU  - J.
AU  - K.
AU  - Bhutta,
AU  - Z.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1159/000542154
L1  - internal-pdf://0822565019/Azhar-2025-Nutritional Management of Low Birth.pdf
PY  - 2025
SP  - 209-223
T2  - Neonatology
TI  - Nutritional Management of Low Birth Weight and Preterm Infants in Low- and Low Middle-Income Countries
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1159%2f000542154
UR  - https://karger.com/neo/article-pdf/122/Suppl. 1/209/4304887/000542154.pdf
VL  - 122
ER  -
TY  - JOUR
AB  - **Objective**: Bipolar disorder (BD) in childhood and adolescence is associated with aggressive behaviors, which might be common and in turn associated with poor clinical outcomes. This is the first systematic review to provide a comprehensive view of the current status of the knowledge about aggressive behaviors in youth with BD. **Method**: We conducted a PRISMA-compliant systematic review of studies investigating aggressive behaviors in children and adolescents with BD (PROSPERO: CRD42023431674). A systematic multi-step literature search was performed on PubMed and the Web of Science. Literature search and data extraction were carried out independently. We provided a systematic synthesis of the findings from the included studies We assessed risk of bias using a modified version of the Newcastle-Ottawa Scale for cross-sectional and cohort studies. **Results**: Of the 2,277 identified records 35 were included; mean age was 12.4 years, and 57.1% were male individuals. 7 studies reported on the prevalence of aggressive behavior among BD children and adolescent population, with 5 of them reporting a prevalence of over 69.0%. Aggressive behaviors were more common in children and adolescents with BD than in those with ADHD or depression. Aggressive behaviors were associated with borderline personality disorder features and poor family functioning. Valproic acid received empirical support for its efficacy in reducing aggressive behavior in BD. **Conclusion**: Aggressive behaviors are prevalent among youth with BD and warrant clinical attention and specific evidence-based management. Further research on prognostic factors and psychosocial interventions evaluated prospectively is required. **Diversity & Inclusion Statement**: One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented sexual and/or gender groups in science. One or more of the authors of this paper self-identifies as living with a disability. We actively worked to promote sex and gender balance in our author group. We actively worked to promote inclusion of historically underrepresented racial and/or ethnic groups in science in our author group.
AN  - 40109487
AU  - Aymerich,
AU  - C.
AU  - Bullock,
AU  - E.
AU  - Rowe,
AU  - S.
AU  - M.
AU  - B.
AU  - Catalan,
AU  - A.
AU  - Salazar
AU  - de
AU  - Pablo,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.jaacop.2024.02.009
L1  - internal-pdf://2366331035/Aymerich-2025-Aggressive Behavior in Children.pdf
PY  - 2025
SP  - 42-55
T2  - JAACAP Open
TI  - Aggressive Behavior in Children and Adolescents With Bipolar Spectrum Disorder: A Systematic Review of the Prevalence, Associated Factors, and Treatment
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.1016%2fj.jaacop.2024.02.009
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11914919/pdf/main.pdf
VL  - 3
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Hyperbaric oxygen therapy (HBOT) is considered a potential treatment for autism spectrum disorders, aiming to improve the underlying pathophysiological mechanisms. It has been studied in several clinical trials, but the effectiveness is still controversial. **PURPOSE**: This systematic review aimed to systematically evaluate the effectiveness of hyperbaric oxygen therapy in the treatment of autism in children and adolescents. **METHODS**: We systematically searched seven databases (PubMed, Embase, Cochrane Libraries, Web of Science, CNKI, Wanfang, and SinoMed) up to March 20, 2024, as well as references lists. The included studies evaluated the effect of HBOT on improving the core symptoms of autism and other specific symptoms (e.g., communication, sociability, cognitive awareness, behavior), including RCTs and quasiexperimental studies. The Cochrane Collaboration's Risk of Bias Assessment Tool for Randomized Trials (RoB2.0) and the JBI Risk of Bias Tool for Quasi-Experimental Studies were used as quality assessment tools. A random effects model was used to conduct a meta-analysis of the core and specific symptoms of autism. Sensitivity analyses and meta-regression were performed to identify sources of heterogeneity and assess result robustness. A Grading of Recommendations Assessment, Development, and Evaluation (GRADE) evidence certainty analysis was performed for outcomes. This systematic review is registered with PROSPERO (CRD42024527220). **RESULTS**: A total of 17 studies with 890 patients were ultimately included in the metaanalysis. The meta-analysis revealed moderately large, significant effects of hyperbaric oxygen therapy, reducing core symptoms of autism [SMD=-0.66, 95% CI (-1.04, -0.28), P=0.0006], and improving three aspects of daily performances (communication [SMD=-0.88, 95% CI (-1.71,-0.04), P=0.04], cognitive awareness [SMD=-0.93, 95% CI (-1.51, -0.35), P=0.002], and behavior [SMD=-0.80, 95% CI (- 1.46, -0.13), P=0.02] in children and adolescents with autism. This systematic review and meta-analysis have limitations such as poor quality and high heterogeneity of the included study. **CONCLUSION**: These findings underscore the potential benefits of hyperbaric oxygen therapy in managing autism-related symptoms and improving daily functioning in affected children and adolescents. Future rigorously designed, high-quality studies are required to confirm the efficacy of hyperbaric oxygen therapy and establish standard treatment protocols.
AN  - 39826608
AU  - Tu,
AU  - P.
AU  - Halili,
AU  - X.
AU  - Zhang,
AU  - S.
AU  - Yang,
AU  - J.
AU  - Xiao,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.pnpbp.2025.111257
L1  - internal-pdf://1517524023/b0162778-e7d7-44ba-ac88-979548b93fbb.pdf
PY  - 2025
SP  - 111257
T2  - Progress in Neuro-Psychopharmacology & Biological Psychiatry
TI  - The effectiveness of hyperbaric oxygen therapy in children and adolescents and with autism spectrum disorders: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.pnpbp.2025.111257
UR  - https://www.sciencedirect.com/science/article/pii/S0278584625000119?via%3Dihub
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Traditional gamified interventions and serious games have been widely employed by therapists and researchers working with people with autism spectrum disorder. Recent studies have also indicated a trend towards technology-based gamification for training behavioral and social skills in autistic people. Nevertheless, the effectiveness of these gamified interventions in enhancing social interaction and communication outcomes among autistic people remains unclear. **OBJECTIVE**: This systematic review and meta-analysis of existing gamified interventions focused on people with autism spectrum disorder aimed to provide an overview of commonly used gamification elements and features for enhancing their social interaction and communication outcomes. **METHODS**: A total of 11 bibliographic databases were systematically searched from inception to April 2024. Experimental studies, including but not limited to randomized controlled trials, quasi-experimental studies (e.g., non-randomized studies, pre-post studies), and pilot studies. Medical Subject Heading terms, keywords, and free words such as 'ASD', 'gamification', and 'social interaction and communication' were used for the search. The extracted data were subjected to a narrative synthesis, and the study outcomes were subjected to a meta-analysis. Gamified elements were classified based on the most widely adopted gamification elements for learning purposes. **RESULTS**: Twenty studies involving 349 participants were eligible. Of 297 participants included for descriptive synthesis, 246 (82.8 %) were male, with a mean age at study entry of 11.55 years. Children and adolescents with autism spectrum disorder were the most common target populations (k = 19, 95 %), followed by the general adult population (k = 1, 5 %). Two main themes related to the application of gamification interventions emerged from the included studies: the augmentation of engagement in the intervention and the amplification of the desired interventional outcomes. Commonly used gamification elements included feedback (k = 10, 50 %), rewards (k = 10, 50 %), custom learning (k = 9, 45 %), monitoring (k = 9, 45 %), and personalization (k = 8, 40 %). Four of the included studies applied 5-7 elements in their interventions. Five studies were included in the meta-analysis, showing a positive overall effect of gamified interventions on social interaction and communication (pooled standardized mean difference: 0.46; 95 % CI 0.08, 0.85; I<sup>2</sup> 0%). **CONCLUSION**: This study offers a comprehensive review of gamification elements and gamified interventions currently used in social interaction and communication skills among people with autism spectrum disorder. The potential benefits of included studies targeting social interaction and communication skills highlight the need for further in-depth investigation in this group. Future randomized controlled trials with more comprehensive development and trials that apply game-related design are suggested.
AN  - 40043470
AU  - Wang,
AU  - T.
AU  - Ma,
AU  - H.
AU  - Ge,
AU  - H.
AU  - Sun,
AU  - Y.
AU  - Kwok,
AU  - T.
AU  - T.
AU  - Liu,
AU  - X.
AU  - Wang,
AU  - Y.
AU  - Lau,
AU  - W.
AU  - K.
AU  - W.
AU  - Zhang,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.ijnurstu.2025.105037
L1  - internal-pdf://1923045500/1-s2.0-S002074892500046X-main.pdf
PY  - 2025
SP  - 105037
T2  - International Journal of Nursing Studies
TI  - The use of gamified interventions to enhance social interaction and communication among people with autism spectrum disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1016%2fj.ijnurstu.2025.105037
UR  - https://www.sciencedirect.com/science/article/pii/S002074892500046X?via%3Dihub
VL  - 165
ER  -
TY  - JOUR
AB  - Social skills training (SST) is a widely proposed intervention to address social impairments in autism spectrum disorder (ASD). SST employs a series of activities aiming to enhance pro-social behaviors. A promising approach to evaluate SST's effects lays on social responsiveness (SR) indicators, which are related to the capacity to respond appropriately to social stimuli. Despite the widespread use of SST, there are no integrative studies evaluating its effects on the SR of ASD people. We performed a systematic review with meta-analysis investigating the effects of SSTs in SR indicators of individuals with ASD. PRISMA guidelines were considered to search through EMBASE, PubMed, PsycINFO, and Scopus without timeframes or language restrictions. Randomized controlled trials (RCTs) were included only. Jamovi (version 1.6) was used to perform the meta-analysis with the standardized mean difference (SMD) between pre and post-intervention scores () as the outcome measure. Twenty-seven papers composed the review and 25 the meta-analysis. The population was predominantly male (80%), with a mean age of 13.03 years. Interventions were mostly conducted in group settings. Meta-analysis indicated the set of interventions as capable of improving SR indicators of ASD people (SMD = 0.57 (CI 95% 0.46-0.67; p < 0.0001). Although our findings cannot support PEERS program as quantitatively superior to other programs, its methodological consistency, treatment adherence and involvement of parents are noteworthy. SST appears to be a viable, versatile, and easily implementable intervention to improve SR of individuals with ASD.
AN  - 40153036
AU  - Anchieta,
AU  - M.
AU  - V.
AU  - Torro-Alves,
AU  - N.
AU  - da
AU  - Fonseca,
AU  - E.
AU  - K.
AU  - G.
AU  - de
AU  - Lima
AU  - Osorio,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1007/s00787-025-02697-7
L1  - internal-pdf://0025385021/Anchieta-2025-Effects of social skills trainin.pdf
PY  - 2025
SP  - 28
T2  - European Child & Adolescent Psychiatry
TI  - Effects of social skills training on social responsiveness of people with Autism spectrum disorder: a systematic review with meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs00787-025-02697-7
UR  - https://link.springer.com/article/10.1007/s00787-025-02697-7
UR  - https://link.springer.com/content/pdf/10.1007/s00787-025-02697-7.pdf
VL  - 28
ER  -
TY  - JOUR
AB  - **INTRODUCTION**: Various antibullying strategies have emerged in the literature. To date, there is a dearth of the quality of evidence on the effectiveness of current antibullying programmes in reducing the sequelae of bullying. This critical appraisal examines the effectiveness of bullying in alleviating social isolation, loneliness and posttraumatic stress disorder (PTSD) among schoolchildren. **METHODS**: This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines. Several databases were searched, and inclusion and exclusion criteria were applied to the articles selected for inclusion. **RESULTS**: Out of the 9537 articles initially identified and after assessing the eligibility of the studies, 22 articles were included in this systematic review, and 10 experimental studies were used for the meta-analysis. There was a significant (p = 0.015) and small standardized mean difference (SMD) (SMD = -0.132, 95% CI = -0.026 to -0.238) of the effect of psycho-educational programmes on social isolation among school children. Additionally, there was a significantly small SMD of the effect of psycho-educational programmes on loneliness among school students (SMD = -0.215, p = 0.049, 95% CI = -0.001 to -0.429). There were not enough publications to perform a meta-analysis of the effects of psycho-educational programmes on PTSD symptoms in school children. **CONCLUSIONS**: Although psycho-educational interventions exhibit promise in mitigating social isolation and loneliness, additional research is required to comprehend their efficacy and comprehensively determine the optimal implementation strategies.
AN  - 40098599
AU  - Al-Alawi,
AU  - K.
AU  - S.
AU  - Eltayib,
AU  - R.
AU  - A.
AU  - A.
AU  - Al
AU  - Saadoon,
AU  - M.
AU  - Alhaj,
AU  - A.
AU  - H.
AU  - Aldhafri,
AU  - S.
AU  - Al-Adawi,
AU  - S.
AU  - Chan,
AU  - M.
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1111/cch.70062
L1  - internal-pdf://1505646622/subito-le25040700301.pdf
PY  - 2025
SP  - e70062
T2  - Child: Care, Health & Development
TI  - Efficacy of Psycho-Educational Interventions on School Bullying in Social Isolation, Loneliness and PTSD Among Schoolchildren: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1111%2fcch.70062
UR  - https://onlinelibrary.wiley.com/doi/10.1111/cch.70062
VL  - 51
ER  -
TY  - JOUR
AB  - A metacognitive learner acts in a planful way, monitors their progress, flexibly adapts their strategies, and reflects on their learning. Unsurprisingly, a metacognitive approach to learning is an important predictor of children's academic performance and many attempts have been made to promote metacognition in young children. The current meta-analytic study evaluates the impact of such metacognition interventions on outcomes related to self-regulated learning and academic achievement in typically developing pre- and elementary school children. Structural, content-related, and methodological moderators were tested in this study including 349 effect sizes from 67 studies. An overall effectiveness of metacognition interventions was evidenced at immediate post-test g = 0.48 (95% CI [0.35, 0.61]), and at follow-up g = 0.29 (95% CI [0.17, 0.40]). Interestingly, metacognition interventions effectively enhanced children's self-efficacy only at follow-up, suggesting that the positive impact of these interventions can unfold over a protracted period. For the first time, children's executive functions were considered as outcome variables and results indicated a positive impact of metacognition interventions on these variables. One notable finding was that interventions that were delivered by teachers or task materials were more effective than interventions that were delivered by researchers for two outcomes related to self-regulated learning. This finding may reflect recent improvements in how teachers and researchers collaborate to develop intervention programs. The study supports and extends existing evidence that young learners benefit from metacognition interventions in myriad ways and provides novel insights relevant for pedagogical practice and theories of self-regulated learning.
AN  - WOS:001388504500001
AU  - Eberhart,
AU  - J.
AU  - Schäfer,
AU  - F.
AU  - Bryce,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1007/s11409-024-09405-x
L1  - internal-pdf://3650353096/Eberhart-2025-Are metacognition interventions.pdf
PY  - 2025
SP  - 45
T2  - Metacognition and Learning
TI  - Are metacognition interventions in young children effective? Evidence from a series of meta-analyses
UR  - <Go to ISI>://WOS:001388504500001
UR  - https://link.springer.com/content/pdf/10.1007/s11409-024-09405-x.pdf
VL  - 20
ER  -
TY  - JOUR
AB  - Considering the potential detrimental impact of poverty on psychological development and the resulting harmful cycles, implementing poverty alleviation interventions is necessary for children and adolescents. Although several meta-analyses have demonstrated the effectiveness of monetary poverty reduction programs, there remains a significant gap in understanding how multidimensional poverty reduction strategies boost psychological development. This meta-analysis aims to address this gap by disclosing the impact of multifaceted anti-poverty interventions on the psychological development of children and adolescents. A comprehensive search was conducted through 12 electronic databases. This review identified nine studies, which included a variety of intervention elements such as educational support, skill training, and cognitive cultivation, and collectively involved 1434 participants. A random effect model by RevMan v5.4 software was adapted to carry out the meta-analysis. The findings reveal a significant effect of anti-poverty programs on promoting positive psychological development (e.g. resilience, grit, and self-esteem) and mitigating negative psychological outcomes (e.g. depression, anxiety and disengagement). Subgroup analyses showed that smaller groups (100 or fewer participants) led to greater improvements in positive psychological outcomes. Professional providers (e.g., psychologists, social workers) had a stronger impact on improving positive psychological outcomes, while non-professional providers (e.g., school teachers) were more effective at alleviating psychological difficulties.
AN  - 39870971
AU  - Li,
AU  - C.
AU  - Xu,
AU  - S.
AU  - Cheng,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1007/s10964-025-02146-3
L1  - internal-pdf://2478707613/Li-2025-Effectiveness of Poverty Reduction Pro.pdf
PY  - 2025
SP  - 27
T2  - Journal of Youth & Adolescence
TI  - Effectiveness of Poverty Reduction Programs on Psychological Development of Children and Adolescents at Risk of Poverty: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs10964-025-02146-3
UR  - https://link.springer.com/article/10.1007/s10964-025-02146-3
UR  - https://link.springer.com/content/pdf/10.1007/s10964-025-02146-3.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - Chinese societies, encompassing Hong Kong, mainland China, Macau, and Taiwan, face growing challenges concerning the mental health of youth. Despite increasing scholarly interest and governmental policy emphasis on youth mental health prevention and promotion programs to address such concerns, there remains insufficient evidence on the synthesized effectiveness of current programs across Chinese societies, due to the lack of thorough reviews and methodological limitation in existing analyses. This systematic review and meta-analysis identified and evaluated studies that used experimental or quasi-experimental designs to examine the characteristics, quality, implementation, and efficacy of existing evidence-based prevention and promotion programs targeting mental health and well-being among youth aged 12 to 18 in Chinese societies. The study screened 3,448 studies identified through searches in both English and Chinese databases, of which 52 met the systematic review inclusion criteria. Included studies encompassed 39255 youth residing in mainland China, Hong Kong, and Taiwan, as no studies were found in Macau. The majority of the included studies were school-based (n = 50), addressed multiple mental health outcomes (n = 46), used randomized trials (n = 37), and conducted in mainland China (n = 26). Overall risk of bias assessment indicated an average quality score of 7.33 (SD = 1.08) for all included studies, with several criteria on participant recruitment, follow-up, and data analysis remained significant threats across studies. While schoolteachers were the primary implementers for many programs (n = 30), scant information regarding implementation support and process was available. Pooled effects regressions by outcome across included studies (n = 30) showed statistically significant effect on reducing externalizing behaviors, particularly substance use among youth. Included programs also demonstrated small effects on youth's coping skills (i.e., drug resistance and positive coping behaviors) and social and emotional competencies (i.e., self-esteem and self-efficacy). No effects were found on the reduction of internalizing problems and behaviors, including anxiety, stress, and depression. The findings show promise for high-quality youth mental health prevention and promotion programs in Chinese societies aimed at promoting mental well-being, whereas preventing internalizing symptoms remains challenging. Furthermore, findings reveal that the prevailing study quality risks and lack of attention on implementation issues might pose additional threats to many current programs. Future scholars should pay close attention to addressing methodological quality and implementation challenges when designing and delivering mental health prevention and promotion programs for youth across Chinese societies.
AN  - WOS:001399429000001
AU  - Yang,
AU  - Y.
AU  - B.
AU  - Fu,
AU  - L.
AU  - Y.
AU  - Cheng,
AU  - S.
AU  - Y.
AU  - Fowler,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1007/s40894-024-00254-y
L1  - internal-pdf://0125558796/Yang-2025-Youth Mental Health Prevention and P.pdf
PY  - 2025
SP  - 40
T2  - Adolescent Research Review
TI  - Youth Mental Health Prevention and Promotion Programs in Chinese Societies: A Systematic Review and Meta-Analysis
UR  - <Go to ISI>://WOS:001399429000001
UR  - https://link.springer.com/article/10.1007/s40894-024-00254-y
UR  - https://link.springer.com/content/pdf/10.1007/s40894-024-00254-y.pdf
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Selective serotonin reuptake inhibitors (SSRIs) are the first choice in pharmacotherapy for children and adolescents with obsessive-compulsive disorder (OCD). SSRI trials for pediatric OCD have not been investigated using individual participant data (IPD), which is crucial for detecting patient-level effect modifiers. This study performed an IPD meta-analysis of efficacy of SSRIs compared with placebo and a meta-regression on baseline patient characteristics that might modify efficacy. **METHOD**: Crude participant data from short-term, randomized, placebo-controlled SSRI trials for pediatric OCD were obtained from the registry of the Dutch regulatory authority. A systematic literature search was also performed, and authors were approached to provide IPD. A 1- and 2-stage analysis was conducted, with change on Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) as the primary outcome. Odds ratio (OR) with >=35% CY-BOCS reduction was used as the responder outcome measure. Modifying effect of age, sex, weight, duration of illness, family history, and baseline symptom severity was examined. The Cochrane RoB 2.0 tool was used to examine methodological rigor, and Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to examine certainty of evidence. **RESULTS**: Data were obtained from 4 studies comprising 614 patients. The sample represented 86% of all participants ever included in double-blind placebo-controlled SSRI trials for pediatric OCD. Meta-analysis showed reduction of 3.0 CY-BOCS points compared with placebo (95% CI 2.5-3.5), corresponding to a small effect size (0.38 Hedges' g). Analysis of response showed an odds ratio of 1.89 (95% CI 1.45-2.45). Of all possible modifiers, severity was correlated negatively with odds ratio for response (beta = -0.92, p = .0074). Risk of bias was generally low. All studies were performed in North America with an overrepresentation of White participants. Findings were limited by inability to include data on additional variables such as socioeconomic status and comorbidities. **CONCLUSION**: This IPD meta-analysis showed a small effect size of SSRIs in pediatric OCD, with baseline severity as a negative modifier of response. Generalizability of findings might be limited by selective inclusion of White, North American participants. **STUDY REGISTRATION INFORMATION**: Patient Characteristics and Efficacy of SSRI Treatment in Children and Adolescents With Obsessive Compulsive Disorder: An Individual Participant Data Meta-analysis of Randomized, Placebo-Controlled Trials; https://www.crd.york.ac.uk; CRD42023486079.
AN  - 39799995
AU  - Cohen,
AU  - S.
AU  - E.
AU  - de
AU  - Boer,
AU  - A.
AU  - Storosum,
AU  - B.
AU  - W.
AU  - C.
AU  - Mattila,
AU  - T.
AU  - K.
AU  - Niemeijer,
AU  - M.
AU  - J.
AU  - Geller,
AU  - D.
AU  - A.
AU  - Denys,
AU  - D.
AU  - Zantvoord,
AU  - J.
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.jaac.2025.01.001
L1  - internal-pdf://3461541114/068e0d87-080a-4f6c-9086-4256c2dbe118.pdf
PY  - 2025
SP  - 10
T2  - Journal of the American Academy of Child & Adolescent Psychiatry
TI  - Systematic Review and Meta-analysis of Individual Participant Data: Randomized, Placebo-Controlled Trials of Selective Serotonin Reuptake Inhibitors for Pediatric Obsessive-Compulsive Disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.jaac.2025.01.001
UR  - https://www.sciencedirect.com/science/article/pii/S0890856725000024?via%3Dihub
VL  - 10
ER  -
TY  - JOUR
AB  - **Objective**: This study aimed to systematically review the available evidence on the effects of exercise training programs on sleep quality in attention deficit hyperactivity disorder. **Methods**: Studies were searched in five electronic databases until March 2024. The methodological quality of the included studies was assessed using the Physiotherapy Evidence Database and Methodological Index for Non-Randomized Studies scales. **Results**: A total of five randomized clinical trials, two non-randomized comparative studies, and one single-arm trial were included. Self-reported sleep quality (n = 7) and objective sleep status (n = 3) were the main outcomes analyzed. Generally, exercise induced positive effects on self-reported sleep outcomes. The performed meta-analysis with data from 131 participants indicated that exercise showed a non-significant trend towards increasing objective sleep duration (Hedges' g -2.67; 95% CI -11.33; 5.99, p = 0.185). While exercise appears safe for individuals with attention deficit hyperactivity disorder, its efficacy in managing sleep disturbances in this population remains uncertain. **Conclusions**: While there is evidence suggesting a positive impact of exercise on self-reported sleep quality, its efficacy for improving sleep duration could not be confirmed.
AN  - 40003220
AU  - Gonzalez-Devesa,
AU  - D.
AU  - Sanchez-Lastra,
AU  - M.
AU  - A.
AU  - Outeda-Monteagudo,
AU  - B.
AU  - Diz-Gomez,
AU  - J.
AU  - C.
AU  - Ayan-Perez,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3390/children12020119
L1  - internal-pdf://0973859890/Gonzalez-Devesa-2025-Effectiveness of Exercise.pdf
PY  - 2025
SP  - 22
T2  - Children
TI  - Effectiveness of Exercise on Sleep Quality in Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.3390%2fchildren12020119
UR  - https://mdpi-res.com/d_attachment/children/children-12-00119/article_deploy/children-12-00119-v2.pdf?version=1737625881
VL  - 12
ER  -
TY  - JOUR
AB  - Most people with mental health needs cannot access treatment; among those who do, many access services only once. Accordingly, single-session interventions (SSIs) may help bridge the treatment gap. We conducted the first umbrella review synthesizing research on SSIs for mental health problems and service engagement in youth and adults. Our search yielded 24 systematic reviews of SSIs, which included 415 unique trials. Twenty reviews (83.33%) reported significant, positive effects of SSIs for one or more outcomes (anxiety, depression, externalizing problems, eating problems, substance use, treatment engagement or uptake). Across 12 reviews that meta-analytically examined SSIs' effectiveness relative to controls, SSIs showed a positive effect across outcomes and age groups (standardized mean difference = -0.25, I2 = 43.17%). Per AMSTAR 2 (A Measurement Tool to Assess Systematic Reviews), some methodological concerns emerged across reviews, such as low rates of preregistration. Overall, findings support the clinical utility of SSIs for certain psychological problems and populations. Implementation research is needed to integrate effective SSIs into systems of care.
AN  - 39874601
AU  - Schleider,
AU  - J.
AU  - L.
AU  - Zapata,
AU  - J.
AU  - P.
AU  - Rapoport,
AU  - A.
AU  - Wescott,
AU  - A.
AU  - Ghosh,
AU  - A.
AU  - Kaveladze,
AU  - B.
AU  - Szkody,
AU  - E.
AU  - Ahuvia,
AU  - I.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1146/annurev-clinpsy-081423-025033
L1  - internal-pdf://1938375574/dfcb9dfb-d3c3-4655-ac1b-ac17746b220f.pdf
PY  - 2025
SP  - 28
T2  - Annual Review of Clinical Psychology
TI  - Single-Session Interventions for Mental Health Problems and Service Engagement: Umbrella Review of Systematic Reviews and Meta-Analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1146%2fannurev-clinpsy-081423-025033
VL  - 28
ER  -
TY  - JOUR
AB  - Previous studies have indicated wide variation in the effectiveness of cognitive and behaviour therapies (CBTs) for preventing and treating anxiety disorders in children and adolescents, indicating the presence of moderators influencing outcomes. This meta-analysis investigated whether sample characteristics (child age, child baseline anxiety levels, parental baseline anxiety levels) and intervention characteristics (intervention duration, facilitator contact time, facilitator background, delivery formats, parental involvement) moderate the effectiveness of CBTs for universal prevention, targeted prevention, and treatment of anxiety disorders in children and adolescents. We identified 86 eligible randomized controlled trials (RCTs) assessing the effectiveness of 98 CBTs versus non-active controls. Effect sizes were the post-intervention standardized mean difference of children's broad anxiety symptoms between CBT and non-active controls. Moderation analyses were conducted separately on child- and parent-reported outcomes using meta-regression and subgroup analyses. We found some evidence for (1) a moderating role of child age, facilitator background, and parental involvement on the effectiveness of CBTs for universal prevention; (2) a moderating role of child age and intervention duration on the effectiveness of CBTs for targeted prevention; (3) a moderating role of child age, facilitator contact time, and delivery formats on the effectiveness of CBTs for treatment. There was no evidence for a moderating role of child baseline anxiety levels on the effectiveness of CBTs for universal/targeted prevention or treatment. The moderating role of parental baseline anxiety levels and its potential interaction with parental involvement was not tested given the limited available data. Although these findings provide insights into the question of what works for whom, they should be interpreted cautiously given the limited available data, wide variation in outcomes, potential confounders, and discrepancies between child- and parent-reported outcomes.
AN  - 39799802
AU  - Zhou,
AU  - S.
AU  - Creswell,
AU  - C.
AU  - Kosir,
AU  - U.
AU  - Reardon,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.cpr.2025.102548
L1  - internal-pdf://1553050066/b99671ea-ccc7-4983-9119-568ec70e57d1.pdf
PY  - 2025
SP  - 102548
T2  - Clinical Psychology Review
TI  - Moderators of cognitive and behaviour therapies for prevention and treatment of anxiety disorders in children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.cpr.2025.102548
UR  - https://www.sciencedirect.com/science/article/pii/S0272735825000145?via%3Dihub
VL  - 116
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Physical activity (PA) interventions have been shown to yield positive effects on cognitive functions. However, it is unclear which type of PA intervention is the most effective in children and adolescents with Neurodevelopmental Disorders (NDDs). This study aimed to compare the effectiveness of different types of PA interventions on cognitive functions in children and adolescents with NDDs, with additional analyses examining intervention effects across specific NDD types including attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). **METHODS**: In this systematic review and network meta-analysis, seven databases (Web of Science, PubMed, Medline, APA PsycINFO, Embase, CINAHL, and SPORTDiscus) for randomized controlled trials from database inception to September 2023 were searched. Randomized controlled trials comparing the effectiveness of PA intervention with any non-pharmacological treatment or control group on cognitive functions in children and adolescents diagnosed with NDDs aged 5-17 years were included. Frequentist network meta-analyses were performed based on standardized mean differences (SMD) using random effects models to examine post-intervention differences in cognitive functions, including attention, memory, and executive functions. Intervention dropout was assessed as a measure of treatment acceptability. **RESULTS**: Thirty-one randomized controlled trials (n = 1,403, mean age 10.0 +/- 1.9 years) with 66 arms were included in the network. Mind-body exercise (MBE; SMD = 1.91 for attention; 0.92 for executive functions), exergaming (SMD = 1.58 for attention; 0.97 for memory; 0.94 for executive functions), and multi-component physical activity (MPA; SMD = 0.79 for executive functions) were associated with moderate to substantial cognitive improvements compared with usual care, whereas the effectiveness of aerobic exercise (AE) was non-significant. Exergaming (SMD = 0.78, 95%CI 0.12 to 1.45) and MPA (SMD = 0.64, 95%CI 0.11 to 1.18) were more effective than AE for executive functions. When analyzing specific NDD types, exergaming lost its superiority over usual care for attention and memory in ADHD, nor for executive functions in ASD. Instead, MPA demonstrated significant benefits across these domains and populations. The certainty of evidence for these comparisons was very low to low. No significant differences in acceptability were observed among MBE, exergaming, and MPA. **CONCLUSIONS**: The findings in this study suggest that MBE, exergaming, and MPA were effective interventions for improving domain-specific cognitive functions in children and adolescents with NDDs. AE demonstrated non-significant effectiveness for all outcomes. MBE emerges as particularly advantageous for attention. MPA yielded consistent improvements in memory and executive functions across NDD types. Further high-quality randomized controlled trials of direct comparisons are needed to confirm and expand on the findings from this NMA. **TRIAL REGISTRATION**: PROSPERO CRD42023409606.
AN  - 39806448
AU  - Tao,
AU  - R.
AU  - Yang,
AU  - Y.
AU  - Wilson,
AU  - M.
AU  - Chang,
AU  - J.
AU  - R.
AU  - Liu,
AU  - C.
AU  - Sit,
AU  - C.
AU  - H.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1186/s12966-024-01702-7
L1  - internal-pdf://0050040926/Tao-2025-Comparative effectiveness of physical.pdf
PY  - 2025
SP  - 6
T2  - International Journal of Behavioral Nutrition & Physical Activity
TI  - Comparative effectiveness of physical activity interventions on cognitive functions in children and adolescents with Neurodevelopmental Disorders: a systematic review and network meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1186%2fs12966-024-01702-7
UR  - https://ijbnpa.biomedcentral.com/counter/pdf/10.1186/s12966-024-01702-7.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - We aimed to analyse the available scientific evidence on the effects of exercise programs on sleep quality in autism spectrum condition. Studies were searched in five electronic databases (MEDLINE/PubMed, Web of Science, EBSCOhost Environment Complete, Dialnet Plus and Scopus) until February 2024 (updated in August 2024). A total of ten randomized clinical trials were included. The pooled mean difference for subjective sleep duration (Child's Sleep Habits Questionnaire [CSHQ] sub-scale), total CSHQ score, objective sleep duration and objective efficiency were - 1.62 points (95 % confidence interval [CI] - 2.34 to - 0.91; p < 0.001), -9.43 points (95 % CI: -16.89 to -1.97, p < 0.001), 0.42 h (95 % CI: 0.05-0.80, p = 0.03) and 9.91 % (95 % CI: 5.04-14.78, p < 0.001), respectively. In conclusion, exercise can serve as an adjunct therapy for managing sleep-related problems among children on the autism spectrum.
AN  - WOS:001361388700001
AU  - González-Devesa,
AU  - D.
AU  - Sanchez-Lastra,
AU  - M.
AU  - A.
AU  - Outeda-Monteagudo,
AU  - B.
AU  - Ayán-Pérez,
AU  - C.
AU  - Diz-Gómez,
AU  - J.
AU  - C.
DB  - Desember 2024.enl
DO  - 10.1016/j.rasd.2024.102516
L1  - internal-pdf://1141636102/f012d349-14ed-4a78-ac4c-9adc8ef16322.pdf
PY  - 2025
SP  - 14
T2  - Research in Autism Spectrum Disorders
TI  - The effect of exercise training on sleep quality in autism spectrum condition: Systematic review and meta-analysis of randomized controlled trials
UR  - <Go to ISI>://WOS:001361388700001
UR  - https://www.sciencedirect.com/science/article/pii/S1750946724001910?via%3Dihub
VL  - 119
ER  -
TY  - JOUR
AB  - By conducting a three-level meta-analysis of 616 randomized effect sizes from 45 studies, it was established that positive discipline interventions significantly contribute to enhancing parenting skills, fostering relationships, constructing a positive school climate, alleviating children's disruptive behaviours, and boosting caregivers' efficacy. The intervention duration and investigative methodology seem to moderate the treatment effects in the negative outcomes. The optimal intervention duration for positive results is less than 10 h, contrasting with 10-20 h for negative outcomes. Groups featuring participants with high-level education backgrounds are likely to experience enhanced intervention effects. Caregivers with children under 8 years of age exhibit a more pronounced effect in reinforcing positive aspects while parents with children aged 8 years or older achieve a more favourable impact in mitigating negative aspects. Compared to other programmes, PD exerts a more significant influence on promoting positive outcomes while less impact on reducing negative outcomes. (PsycInfo Database Record (c) 2025 APA, all rights reserved)
AN  - 2025-65983-001
AU  - Yu,
AU  - Yanni
AU  - Fang,
AU  - Jingwei
AU  - Chen,
AU  - Huan
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1080/03004430.2024.2448678
L1  - internal-pdf://1911071250/Yu-2025-A comprehensive three-level meta-analy.pdf
PY  - 2025
SP  - No Pagination Specified
T2  - Early Child Development and Care
TI  - A comprehensive three-level meta-analysis of the positive discipline programme: Effectiveness and moderating variables
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=psyc23&DO=10.1080%2f03004430.2024.2448678
UR  - https://www.tandfonline.com/doi/full/10.1080/03004430.2024.2448678
UR  - https://www.tandfonline.com/doi/pdf/10.1080/03004430.2024.2448678
ER  -
TY  - JOUR
AB  - Virtual reality (VR) technology provides innovative intervention means for children with autism spectrum disorder (ASD) due to its advantages of realism, flexibility, and controllability, bringing new possibilities. The application of VR technology for intervention in children with ASD has been widely explored. A total of 39 studies reviewed relevant literature from 2006 to February 2024 and found that VR technology demonstrated strong effectiveness in intervention for children with ASD, including social skills, moods and emotions, daily living skills, attention and others. However, existing studies have limitations regarding research methods, participants, theories, and long-term effectiveness. Future research should overcome the limitations of current studies, focusing on weak quality of research methods, targeting female individuals with ASD and individuals with varying levels of functioning, exploring the theoretical foundations of VR-based interventions, and conducting long-term follow-ups to verify intervention effects.
AN  - WOS:001409050400001
AU  - Fu,
AU  - W.
AU  - Q.
AU  - Tao,
AU  - T.
AU  - Wang,
AU  - J.
AU  - Y.
AU  - Peng,
AU  - Z.
AU  - W.
AU  - Wang,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1177/01626434251317984
L1  - internal-pdf://4263908162/Fu-2025-Application of Virtual Reality Technol.pdf
PY  - 2025
SP  - 11
T2  - Journal of Special Education Technology
TI  - Application of Virtual Reality Technology in Intervention for Children With Autism Spectrum Disorder: A Systematic Review
UR  - <Go to ISI>://WOS:001409050400001
ER  -
TY  - JOUR
AB  - Sleep problems occur in up to 20%-45% of adolescents. This systematic review and meta-analysis examined the effectiveness of digital sleep interventions, based on cognitive behavioural therapy for insomnia, for adolescents with insomnia symptoms. The objective was to synthesise and quantify, through meta-analyses, changes in sleep following completion of a digital sleep-based intervention. MEDLINE, PubMed, PsycINFO, Scopus, EMBASE, CENTRAL, and Web of Science databases were searched from January 2012 to March 2024. Within-subject studies or randomized-controlled trials reporting the effects of digital cognitive behavioural therapy for insomnia were included. Risk of bias was assessed using the integrated quality criteria for the review of multiple study designs. Random-effects meta-analyses estimated pooled standardised within-subject mean differences to assess effectiveness. Nine studies involving 486 adolescents were included. Digital cognitive behavioural therapy for insomnia interventions were effective in reducing insomnia symptoms (Hedges' g = 1.40), subjective sleep-onset latency (Hedges' g = 0.72) and waking after sleep onset (Hedges' g = 0.47), and increasing subjective and objective total sleep time (Hedges' g = -0.29 and -0.23, respectively). Other objective measures of sleep did not improve. All studies met the minimum ICROMS score and were considered to be of sufficient quality. Seven within-subject studies failed to satisfy all mandatory criteria. These results suggest that digital cognitive behavioural therapy for insomnia interventions are effective in improving adolescent's perceptions of their sleep, but are less effective at improving some objective measures of sleep. To achieve a clear understanding of how digital cognitive behavioural therapy for insomnia interventions compare with other behavioural interventions, additional high-quality randomized-controlled trials comparing digital cognitive behavioural therapy for insomnia interventions with traditional in-person modalities are needed. (PROSPERO;CRD42021287479).
AN  - WOS:001418990800001
AU  - Cleary,
AU  - M.
AU  - A.
AU  - Richardson,
AU  - C.
AU  - Ross,
AU  - R.
AU  - J.
AU  - Heussler,
AU  - H.
AU  - S.
AU  - Wilson,
AU  - A.
AU  - Downs,
AU  - J.
AU  - Walsh,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1111/jsr.14466
L1  - internal-pdf://3263828396/Cleary-2025-Effectiveness of current digital c.pdf
PY  - 2025
SP  - 19
T2  - Journal of Sleep Research
TI  - Effectiveness of current digital cognitive behavioural therapy for insomnia interventions for adolescents with insomnia symptoms: A systematic review and meta-analysis
UR  - <Go to ISI>://WOS:001418990800001
ER  -
TY  - JOUR
AB  - Children who engage in aggressive behaviors are at heightened risk of being involved in the justice system, committing serious offenses, and becoming chronic offenders. The Stop Now And Plan (SNAP) program was designed as an early intervention to address several mechanisms underlying the development of conduct problems, including emotion regulation, prosocial behaviors, and parent-child relationships. The purpose of this study was to systematically review and synthesize current research on the SNAP program and conduct a meta-analysis. Following PRISMA guidelines, PubMed and PyscINFO were searched, and the developers of SNAP were contacted to ensure no articles were missed. Twenty-two peer-reviewed articles were ultimately included following a two-stage screening process. The meta-analysis revealed a moderate effect size change (SMD = - 0.54, 95% CI [- .42, - .65], p < .001) in externalizing problems from pre- to post-SNAP Group. The narrative review found evidence for decreases in symptoms (e.g., conduct problems, aggression, delinquency, internalizing problems) across SNAP programming. There was also preliminary evidence for changes in proposed mechanisms across the groups (e.g., emotion regulation, parent behaviors, child-parent relationship). Two randomized controlled trials (RCT) supported the efficacy of the SNAP Boys Group over another active treatment. One waitlist control found similar results for the SNAP Girls Group. There is growing evidence for SNAP, attributable to the effective clinical research partnerships established by the developers. More rigorous methods and RCTs will help solidify SNAP as a top evidence-based intervention.
AN  - WOS:001422093000001
AU  - Craig,
AU  - S.
AU  - G.
AU  - Frankiewicz,
AU  - K.
AU  - Stearns,
AU  - N.
AU  - R.
AU  - Girard-Lapointe,
AU  - J.
AU  - Cortese,
AU  - A.
AU  - Vogel,
AU  - N.
AU  - Pepler,
AU  - D.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1007/s11121-025-01788-w
L1  - internal-pdf://2727877425/Craig-2025-What Do We Know About the Stop Now.pdf
PY  - 2025
SP  - 23
T2  - Prevention Science
TI  - What Do We Know About the Stop Now and Plan Program? A Systematic Review and Meta-Analysis of an Early Invention for Children and Youth with Conduct Problems
UR  - <Go to ISI>://WOS:001422093000001
UR  - https://link.springer.com/article/10.1007/s11121-025-01788-w
UR  - https://link.springer.com/content/pdf/10.1007/s11121-025-01788-w.pdf
ER  -
TY  - JOUR
AB  - Pediatric major depressive disorder (MDD) often leads to recurrent depression in adulthood. The efficacy, safety and dose dependency of pharmacological effect is unclear. We conducted a systematic review and dose-response meta-analysis comprising of 22 double-blind randomized controlled trials, the majority of which had short trial durations ranging from 6 to 12 weeks. Studies were identified from PubMed, Ovid Embase, Ovid Medline, Ovid PsycInfo, Wanfang, ClinicalTrial.gov and CENTRAL until July 31, 2023. Doses of all antidepressants were converted to fluoxetine equivalents. Outcomes including treatment response, remission, suicidality, tolerability and acceptability were assessed. Sensitivity analysis, funnel plot and the trim-and fill method are used to assess and adjust for publication bias. Findings revealed that antidepressants were marginally more effective than placebos in terms of treatment response, but significantly increased the risk of adverse effects. No significant differences were observed in remission, suicidality, or overall dropout rates. Dose-response analysis indicated a relatively flat increase in response probability with higher fluoxetine equivalent doses, but also a sharp increase risk of discontinuation due to side effects. This study suggests that antidepressants for pediatric MDD may be less effective in adults, emphasizing the need to balance treatment benefits with potential adverse effects when considering interventions for this population.
AN  - 40056173
AU  - Zhang,
AU  - Y.
AU  - Gao,
AU  - Y.
AU  - Li,
AU  - X.
AU  - Zou,
AU  - Y.
AU  - Ye,
AU  - Y.
AU  - Zou,
AU  - Z.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1007/s00787-025-02688-8
L1  - internal-pdf://4038088781/Zhang-2025-Antidepressant treatment of depress.pdf
PY  - 2025
SP  - 08
T2  - European Child & Adolescent Psychiatry
TI  - Antidepressant treatment of depression in children and adolescents: a systematic review and dose-response meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs00787-025-02688-8
UR  - https://link.springer.com/article/10.1007/s00787-025-02688-8
UR  - https://link.springer.com/content/pdf/10.1007/s00787-025-02688-8.pdf
VL  - 08
ER  -
TY  - JOUR
AB  - In the school environment, young people show a high level of sedentary behaviour. Physical activity has been shown to be beneficial in improving students' quality of life. Moreover, physical activity with cognitive challenges and the implementation of active breaks are effective tools to work on the cognitive development of students in the school environment. The overall aim of this study was to analyse and compare the effect of interventions based on active breaks and cognitively challenging physical tasks to improve executive functions. The search for research was carried out in Web of Science, ERIC, Scopus, PsycINFO, Pubmed and Cochrane Library from May to August 2024. It has been considered studies that applied a physical activity programme with cognitive demands or application of active breaks and that used a randomised controlled trial or controlled trial design. The quantitative synthesis consisted of 22 studies. Two moderating variables were established: physical activities with cognitive demands and the use of active breaks. The application of physical activities with cognitive demands was more effective for working on cognitive flexibility (g = 1.47, CI = [0.70, 2.25]), fluency (g = 1.71, CI = [1.16, 2.27]) and updating (g = 1.05, CI = [-0.96, 3.06]). The application of active breaks was more efficient for attention work (g = 0.74, CI = [0.01, 1.47]), inhibition (g = 1.24, CI = [0.56, 1.92]) and working memory (g = 1.00, CI = [-0.54, 2.55]). It has been concluded that the presence of cognitive load in school physical activities condition the work of different executive functions. (PsycInfo Database Record (c) 2025 APA, all rights reserved)
AN  - 2025-92317-001
AU  - Zurita-Ortega,
AU  - Felix
AU  - Gonzalez-Valero,
AU  - Gabriel
AU  - Ubago-Jimenez,
AU  - Jose
AU  - Luis
AU  - Melguizo-Ibanez,
AU  - Eduardo
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.psicoe.2025.500163
L1  - internal-pdf://1207785642/1-s2.0-S2530380525000012-main.pdf
PY  - 2025
SP  - No Pagination Specified
T2  - Revista de Psicodidactica (English Edition)
TI  - Analysis of cognitively loaded physical tasks and active breaks for the improvement of executive functions in the school context. A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=psyc24&DO=10.1016%2fj.psicoe.2025.500163
UR  - https://www.sciencedirect.com/science/article/pii/S2530380525000012?via%3Dihub
ER  -
TY  - JOUR
AB  - **Objective**: To describe the chronic physical activity at school effects on children and adolescents' cognitive performance, examining different types of intervention in the school environment. **Design**: A systematic review with meta-analysis and meta-regression was conducted including experimental studies reporting the effects of physical activity at school on cognitive performance in children and adolescents. **Data sources**: PubMed, Embase, Scopus, and Cochrane Library from database inception to February 30, 2023. **Eligibility criteria for selecting studies**: Studies with: (P) healthy children and adolescents, (I) interventions with physical activity at school (sports, general physical activity, and physical exercises), (C) a control group, (O) cognitive flexibility, working memory, inhibitory control, and attention outcomes; and (S) Randomised trials of RCTs and longitudinal designs. **Results**: Eighteen studies were included. The interventions were divided into three groups: different team games, general physical activity, and different physical exercises. Physical activity at school was associated with changes in cognitive flexibility (g: 0.244; 95% CI 0.116 to 0.373; p <0.001; I-2 = 0%); in working memory (g: 0.123; 95% CI 0.028 to 0.219; p = 0.012; I-2 = 14%); in inhibitory control (g: 0.122; 95% CI 0.062 to 0.182; p < 0.001; I-2 = 3%); and in attention (g: 0.100; 95% CI 0.040 to 0.161; p < 0.001; I-2 = 0%). **Conclusion**: Our results support that interventions with chronic physical activity at school have a positive effect on cognitive flexibility, inhibitory control, working memory, and attention in children and adolescents. Subgroup analyses established that the impact on each outcome essentially depends on the type of intervention performed. Meta-regression showed that age was a valid predictor of improvements in working memory **Prospero registration**: CRD42021274668.
AN  - WOS:001390150500001
AU  - Mello,
AU  - J.
AU  - B.
AU  - Costa,
AU  - R.
AU  - R.
AU  - da
AU  - Silva,
AU  - F.
AU  - F.
AU  - Martins,
AU  - R.
AU  - Cristi-Montero,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1016/j.edurev.2024.100658
L1  - internal-pdf://3449235174/27ca8cf1-2617-40e7-906c-60d0969f3a0d.pdf
PY  - 2025
SP  - 13
T2  - Educational Research Review
TI  - School ACTIVE, brain active: A meta-analysis and meta-regression on chronic school physical activity effects on cognitive performance in children and adolescents
UR  - <Go to ISI>://WOS:001390150500001
UR  - https://www.sciencedirect.com/science/article/pii/S1747938X24000678?via%3Dihub
VL  - 46
ER  -
TY  - JOUR
AB  - **BACKGROUND**: As digital mental health delivery becomes increasingly prominent, a solid evidence base regarding its efficacy is needed. **OBJECTIVE**: This study aims to synthesize evidence on the comparative efficacy of systemic psychotherapy interventions provided via digital versus face-to-face delivery modalities. **METHODS**: We followed PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for searching PubMed, Embase, Cochrane CENTRAL, CINAHL, PsycINFO, and PSYNDEX and conducting a systematic review and meta-analysis. We included randomized controlled trials comparing mental, behavioral, and somatic outcomes of systemic psychotherapy interventions using self- and therapist-guided digital versus face-to-face delivery modalities. The risk of bias was assessed with the revised Cochrane Risk of Bias tool for randomized trials. Where appropriate, we calculated standardized mean differences and risk ratios. We calculated separate mean differences for nonaggregated analysis. **RESULTS**: We screened 3633 references and included 12 articles reporting on 4 trials (N=754). Participants were youths with poor diabetic control, traumatic brain injuries, increased risk behavior likelihood, and parents of youths with anorexia nervosa. A total of 56 outcomes were identified. Two trials provided digital intervention delivery via videoconferencing: one via an interactive graphic interface and one via a web-based program. In total, 23% (14/60) of risk of bias judgments were high risk, 42% (25/60) were some concerns, and 35% (21/60) were low risk. Due to heterogeneity in the data, meta-analysis was deemed inappropriate for 96% (54/56) of outcomes, which were interpreted qualitatively instead. Nonaggregated analyses of mean differences and CIs between delivery modalities yielded mixed results, with superiority of the digital delivery modality for 18% (10/56) of outcomes, superiority of the face-to-face delivery modality for 5% (3/56) of outcomes, equivalence between delivery modalities for 2% (1/56) of outcomes, and neither superiority of one modality nor equivalence between modalities for 75% (42/56) of outcomes. Consequently, for most outcome measures, no indication of superiority or equivalence regarding the relative efficacy of either delivery modality can be made at this stage. We further meta-analytically compared digital versus face-to-face delivery modalities for attrition (risk ratio 1.03, 95% CI 0.52-2.03; P=.93) and number of sessions attended (standardized mean difference -0.11; 95% CI -1.13 to -0.91; P=.83), finding no significant differences between modalities, while CIs falling outside the range of the minimal important difference indicate that equivalence cannot be determined at this stage. **CONCLUSIONS**: Evidence on digital and face-to-face modalities for systemic psychotherapy interventions is largely heterogeneous, limiting conclusions regarding the differential efficacy of digital and face-to-face delivery. Nonaggregated and meta-analytic analyses did not indicate the superiority of either delivery condition. More research is needed to conclude if digital and face-to-face delivery modalities are generally equivalent or if-and in which contexts-one modality is superior to another. **TRIAL REGISTRATION**: PROSPERO CRD42022335013; https://tinyurl.com/nprder8h.
AN  - 39993307
AU  - Erasmus,
AU  - P.
AU  - Borrmann,
AU  - M.
AU  - Becker,
AU  - J.
AU  - Kuchinke,
AU  - L.
AU  - Meinlschmidt,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.2196/46441
L1  - internal-pdf://2396257624/ijmr-2025-1-e46441.pdf
PY  - 2025
SP  - e46441
T2  - Interactive Journal of Medical Research
TI  - Comparing Digital Versus Face-to-Face Delivery of Systemic Psychotherapy Interventions: Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.2196%2f46441
VL  - 14
ER  -
TY  - JOUR
AB  - This study primarily evaluated the effects of vigorous-intensity exercises on working memory and inhibitory control in children with attention deficit hyperactivity disorder (ADHD). Search for eligible studies through four databases, and then proceed with screening. The inclusion criteria are as follows: (1) Children with ADHD; (2) Randomised controlled trial; (3) The intervention group received exercise, while the control group did not perform any exercises as the treatment; (4) Conducted pre- and post-exercise assessments, which include working memory and inhibitory control parameters. Use the Cochrane bias risk assessment tool to evaluate the quality of the selected study. Select standardized mean difference as the appropriate effect scale index, and use Revman 5.4 software to analyze the mean difference. This study was registered in the PROSPERO (CRD42024597510). A total of ten studies fulfilled the inclusion criteria and were selected for the meta-analysis. The included studies involved 367 males and 159 females, where 273 belonged to the exercise group and 253 from the control group. Participants in the exercise group enhanced working memory [0.37 (0.12, 0.63) p < 0.05, I<sup>2</sup> = 0%] than the control group. In addition, the results indicated that submaximal intensity exercise improved inhibition regulation levels significantly [- 0.34 (- 0.65, - 0.03), p < 0.05, I<sup>2</sup> = 0%]. Based on the systematic meta-analysis results, vigorous-intensity exercises have effective working memory, cognitive function, and motor ability-increasing effects on children with ADHD. Furthermore, Submaximal intensity exercise can effectively improve control inhibition in children with ADHD.
AN  - 40156018
AU  - Zhang,
AU  - R.
AU  - Li,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1186/s13052-025-01924-w
L1  - internal-pdf://1460623484/Zhang-2025-Effect of vigorous-intensity exerci.pdf
PY  - 2025
SP  - 104
T2  - Italian Journal of Pediatrics
TI  - Effect of vigorous-intensity exercise on the working memory and inhibitory control among children with attention deficit hyperactivity disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1186%2fs13052-025-01924-w
UR  - https://ijponline.biomedcentral.com/counter/pdf/10.1186/s13052-025-01924-w.pdf
VL  - 51
ER  -
TY  - JOUR
AB  - **AIM**: To assess the effectiveness of family-centered care (FCC) interventions on motor and neurobehavior development of very preterm infants. **METHOD**: Randomized and quasi-randomized trials assessing the effect of FCC on motor and neurobehavioral outcomes in very preterm infants (28-32 wk gestation) were included. Five electronic databases and grey literature were searched from January 2010 to August 2022. Two reviewers independently screened the titles/abstracts and full texts, assessed the risk of bias, and extracted data. The Cochrane Risk of Bias 2.0 Tool and GRADE were used for risk and evidence certainty assessments. Meta-analysis or narrative synthesis was performed based on data availability and heterogeneity. **RESULTS**: Seventeen trials with 21 publications were included. GRADE showed low to moderate evidence. At 24 months, FCC interventions improved motor development (Mean Difference (MD):5.00, 95% CI: 2.58-7.42), cognitive development (MD: 3.64, 95% CI: 1.15-6.12), and behavior development (MD: -2.40, 95% CI: -4.32, -0.48) compared to control groups. Further, the FCC showed minimal or inconclusive effects on language, communication, and personal social development measured anytime between newborn and 24 months of age. **CONCLUSIONS**: Early initiated FCC interventions can be a promising approach to improve motor, cognition, and behavioral development in very preterm infants.
AN  - 39819163
AU  - Raghupathy,
AU  - M.
AU  - K.
AU  - Parsekar,
AU  - S.
AU  - S.
AU  - Nayak,
AU  - S.
AU  - R.
AU  - Karun,
AU  - K.
AU  - M.
AU  - Khurana,
AU  - S.
AU  - Spittle,
AU  - A.
AU  - J.
AU  - Lewis,
AU  - L.
AU  - E.
AU  - S.
AU  - Rao,
AU  - B.
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1080/01942638.2024.2449387
L1  - internal-pdf://2786737094/f2f8ad88-62d2-459e-a276-857ebef63cf9.pdf
PY  - 2025
SP  - 1-30
T2  - Physical & Occupational Therapy in Pediatrics
TI  - Effect of Family-Centered Care Interventions on Motor and Neurobehavior Development of Very Preterm Infants: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1080%2f01942638.2024.2449387
ER  -
TY  - JOUR
AB  - The purpose of this network meta-analysis (NMA) is to compare the effect of different non-pharmacological interventions (NPIs) on Problematic Internet Use (PIU). Randomized controlled trials (RCTs) published from their inception to 22 December 2023 were searched in Cochrane Central Register of Controlled Trials, Embase, Medline, Web of Science, China National Knowledge Infrastructure, China Science and Technology Journal Database, Chinese BioMedical Literature Database, and WanFang Data. We carried out a data analysis to compare the efficacy of various NPIs using Bayesian NMA. A battery of analyses and assessments, such as conventional meta-analysis and risk of bias, were performed concurrently. Two reviewers extracted data and evaluated bias using the Cochrane Risk of Bias tool independently. We identified 90 RCTs including 15 different NPIs (5986 participants), namely sports intervention (SI), electroencephalogram biological feedback (EBF), reality therapy (RT), positive psychology therapy (PPT), sandplay therapy (ST), educational intervention (EI), compound psychotherapy (CPT), electroacupuncture therapy (AT), group counseling (GC), family therapy (FT), electrotherapy (ELT), craving behavior intervention (CBI), virtual reality therapy (VRT), cognitive behavior therapy (CBT), and mindfulness therapy (MT). Our NMA results showed that SI, EBF, RT, PPT, ST, EI, CPT, AT, GC, FT, ELT, CBT, CBI, VRT, and MT were effective in reducing PIU levels. The most effective NPI was SI (SMD = -4.66, CrI: -5.51, -3.82, SUCRA = 95.43%), followed by EBF (SMD = -4.51, CrI: -6.62, -2.39, SUCRA = 90.89%) and RT (SMD = -3.83, CrI: -6.01, -1.62, SUCRA = 81.90%). Our study showed that SI was the best NPI to relieve PIU levels in youth. Medical staff should be aware of the application of SI to the treatment of PIU in youth in future clinical care.
AN  - 39851902
AU  - Tian,
AU  - J.
AU  - J.
AU  - He,
AU  - X.
AU  - Y.
AU  - Guo,
AU  - Z.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3390/bs15010098
L1  - internal-pdf://2678559314/Tian-2025-Optimal Non-Pharmacological Interven.pdf
PY  - 2025
SP  - 20
T2  - Behavioral Sciences
TI  - Optimal Non-Pharmacological Interventions for Reducing Problematic Internet Use in Youth: A Systematic Review and Bayesian Network Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.3390%2fbs15010098
UR  - https://mdpi-res.com/d_attachment/behavsci/behavsci-15-00098/article_deploy/behavsci-15-00098.pdf?version=1737375664
VL  - 15
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Related issues, such as sleep disturbance, are also frequently reported by children with autism spectrum disorder (ASD). This study systematically reviewed the influences of exercise on sleep and anxiety in children with ASD. **METHODS**: Search for eligible studies through four databases, and then proceed with screening. The inclusion criteria are as follows: 1) Children with ASD; 2) Age 6-14 years; 3) Randomised Controlled Trial (RCT); 4) The experimental (EXP) group received exercise training , while the control (CON) group did not exercise; 5) Conducted pre- and post-test, which include sleep and anxiety. Use the Cochrane bias risk assessment tool to evaluate the quality of the selected study. Select Standardized Mean Difference (SMD) as the appropriate effect scale index, and use Revman 5.4 software to analyze the mean difference of the selected article data. **RESULTS**: A total of seven studies fulfilled the inclusion criteria and were selected for the meta-analysis. The included studies involved 387 males and 79 females. The results demonstrated that the EXP group benefited from the improved sleep [SMD, -1.05 (-1.25, -0.85), p < 0.05, I2 = 27%] and anxiety [SMD, -1.14 (-1.56, -0.72), p < 0.05, I2 = 95%] than the CON group. **CONCLUSION**: According to the findings, exercise intervention could offer non-pharmacological interventions for improving sleep and anxiety in children diagnosed with ASD. Sports training could also be considered to promote the rehabilitation of children patients with ASD, which might provide valuable insights.
AN  - 40107307
AU  - Wang,
AU  - J.
AU  - Li,
AU  - J.
AU  - Wang,
AU  - F.
AU  - You,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1055/a-2561-8487
L1  - internal-pdf://0510810267/a-2561-8487.pdf
PY  - 2025
SP  - 19
T2  - Neuropediatrics
TI  - Exercise Intervention Influences on Sleep and Anxiety in Children with Autism Spectrum Disorder: A meta-analyses of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1055%2fa-2561-8487
UR  - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-2561-8487
VL  - 19
ER  -
TY  - JOUR
AB  - Exercise interventions targeting Fundamental Movement Skills (FMS) represent a critical approach for mitigating functional impairments in children with autism spectrum disorder (ASD). This study, for the first time, based on motor development theory, employed a Network Meta-analysis (NMA) to examine the effects of four types of exercise interventions-Isolation of Fundamental Movement Skills (FMS-I), Combination of Fundamental Movement Skills (FMS-C), Fine Motor Movement (FMM), and Specialized Movement Skills (SMS)-on the core symptoms of ASD in children aged 3-12, including social communication deficits and stereotyped and repetitive behaviors. Five electronic databases were systematically searched up to May 22, 2024. Included studies compared exercise interventions with control groups and assessed at least one core symptom of ASD. Study quality and evidence certainty were evaluated using the Risk of Bias tools (RoB 2.0, ROBINS-I) and the Confidence in Network Meta-Analysis (CINeMA) framework. Data analysis was performed via Stata 17.0 software. The systematic review included 26 studies encompassing 878 children, with 19 studies eligible for NMA. Ranking probabilities indicated that FMS-I emerged as the most promising intervention for addressing social communication deficits (SMD: -0.99, 95%CI: -1.46 to -0.52; SUCRA: 86.9%) and stereotyped and repetitive behaviors (SMD: -2.73, 95% CI: -3.76 to -1.70; SUCRA: 100%). The FMS-C showed potential for enhancing overall features (SMD: -0.90; 95%CI: -1.32 to -0.49; SUCRA: 74.7%). To conclude, exercise interventions should be grounded in FMS, transitioning from isolated movements to integrated actions, to enhance the overall behavior of children with ASD.
AN  - 40131458
AU  - Zhang,
AU  - L.
AU  - Zhang,
AU  - C.
AU  - Yuan,
AU  - X.
AU  - Ji,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1007/s00787-025-02696-8
L1  - internal-pdf://1424709693/Zhang-2025-The impact of exercise intervention.pdf
PY  - 2025
SP  - 25
T2  - European Child & Adolescent Psychiatry
TI  - The impact of exercise interventions on core symptoms of 3-12-year-old children with autism spectrum disorder: a systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs00787-025-02696-8
UR  - https://link.springer.com/article/10.1007/s00787-025-02696-8
UR  - https://link.springer.com/content/pdf/10.1007/s00787-025-02696-8.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - **BACKGROUNDS**: Exposure to adverse childhood experiences (ACEs) is associated with adverse neurobiological, developmental, cognitive, behavioral, psychological, and social consequences among children and adolescents. Psychosocial interventions hold promise for mitigating the negative impacts of ACEs, but there is a lack of updated and comprehensive evidence summarizing their effects qualitatively and quantitatively. **AIMS**: We performed a systematic review and meta-analysis of existing evidence on the effectiveness of psychosocial interventions on children's outcomes, including internalizing and externalizing problems. **METHODS**: We searched five database sources from inception to April 2024 for studies on the effectiveness of any psychosocial intervention in any outcome among children and adolescents aged 6-18 who experienced ACEs. We qualitatively synthesized the characteristics of the studies, samples, interventions, and outcomes. We quantitatively estimated the pooled effects of psychosocial interventions on a range of outcomes encompassing internalizing problems, externalizing problems, family relationships, coping, and self-esteem using meta-analysis. Additionally, we conducted a series of subgroup meta-analyses to compare the intervention effects based on sample and intervention characteristics. **RESULTS**: Forty-four studies were included, with 20 randomized controlled trials, nine controlled trials, and 15 pre-post trials. Significant intervention effects were observed in internalizing problems (standardized mean difference, SMD = -0.36) and externalizing problems (SMD = -0.57), but not in family relationships, coping, or self-esteem. Subgroup analyses have identified various effective interventions for internalizing problems and externalizing problems, respectively. **CONCLUSIONS**: The evidence suggests that psychosocial interventions are effective in preventing internalizing and externalizing problems among children and adolescents who have experienced ACEs. Recommendations are provided for designing and evaluating future psychosocial interventions.
AN  - 39869973
AU  - Mao,
AU  - P.
AU  - Zou,
AU  - Y.
AU  - Hash,
AU  - J.
AU  - Long,
AU  - N.
AU  - Tan,
AU  - M.
AU  - Yang,
AU  - J.
AU  - Yuwen,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.chiabu.2024.107244
L1  - internal-pdf://3975683675/f1025792-f202-4d4c-8626-c2c2c4a903df.pdf
PY  - 2025
SP  - 107244
T2  - Child Abuse & Neglect
TI  - Psychosocial interventions for children and adolescents with adverse childhood experiences: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.chiabu.2024.107244
UR  - https://www.sciencedirect.com/science/article/pii/S0145213424006379?via%3Dihub
VL  - 161
ER  -
TY  - JOUR
AB  - **Background**: People with disabilities are consistently falling behind in educational outcomes compared to their peers without disabilities, whether measured in terms of school enrolment, school completion, mean years of schooling, or literacy levels. These inequalities in education contribute to people with disabilities being less likely to achieve employment, or earn as much if they are employed, as people without disabilities. Evidence suggests that the gap in educational attainment for people with and without disabilities is greatest in low- and middle-income countries (LMICs). Exclusion of people with disabilities from mainstream education, and low rates of participation in education of any kind, are important issues for global equity. Interventions which might have a positive impact include those that improve educational outcomes for people with disabilities, whether delivered in specialist or inclusive education settings. Such interventions involve a wide range of initiatives, from those focused on the individual level – such as teaching assistance to make mainstream classes more accessible to children with specific learning needs – to those which address policy or advocacy.**Objectives**: The objectives of this review were to answer the following research questions: (1) What is the nature of the interventions used to support education for people with disabilities in LMICs? (2) What is the size and quality of the evidence base of the effectiveness of interventions to improve educational outcomes for people with disabilities in LMICs? (3) What works to improve educational outcomes for people with disabilities in LMICs? (4) Which interventions appear to be most effective for different types of disability? (5) What are the barriers and facilitators to the improvement of educational outcomes for people with disabilities? (6) Is there evidence of cumulative effects of interventions? **Search Methods**: The search for studies followed two steps. Firstly, we conducted an electronic search of databases and sector-specific websites. Then, after initial screening, we examined the reference lists of all identified reviews and screened the cited studies for inclusion. We also conducted a forward search and an ancestral search. No restrictions in terms of date or format were placed on the search, but only English-language publications were eligible for inclusion. **Selection Criteria**: In our review, we included studies on the basis that they were able to detect intervention impact. Descriptive studies of various designs and methodologies were not included. We also excluded any study with a sample size of fewer than five participants. We included studies which examined the impact of interventions for people with disabilities living in LMICs. There were no restrictions on comparators/comparison groups in included studies. However, to be eligible for inclusion, a study needed to have both an eligible intervention and an eligible outcome. Any duration of follow-up was eligible for inclusion. **Data Collection and Analysis**: We used EppiReviewer for bibliographic management, screening, coding, and data synthesis. Eligibility was assessed using a predesigned form based on the inclusion criteria developed by the authors. We piloted all coding sheets with at least five studies before use. The form allowed for coding of multiple intervention domains and multiple outcomes domains. The entire screening process was reported using a PRISMA flow chart. We screened all unique references from our search title and abstract, with two independent reviewers determining relevance, and repeated this process for full texts. Data was extracted from studies according to a coding sheet. Coding included: (1) extraction of basic study characteristics, (2) a narrative summary of procedures and findings (including recording of iatrogenic effects), (3) a summary of findings/results table, (4) an assessment of confidence in study findings, and (5) creation of a forest plot of effect sizes. A third data collector, a research associate, checked the results of this process. Confidence in study findings was assessed using a standardised tool. All coding categories were not mutually exclusive and so multiple coding was done where an intervention covered more than one category of intervention. **Main Results**: Twenty-eight studies were included in this review. Most studies (n = 25) targeted children with disabilities. Only two studies directly targeted family members, and the remaining three focused on service providers. Individuals with intellectual or learning and developmental impairments were most frequently targeted by interventions (n = 17). The category of interventions most represented across studies was ‘Educational attainment support’, for instance, a reading comprehension intervention that combined strategy instruction (graphic organisers, visual displays, mnemonic illustrations, computer exercises, predicting, inference, text structure awareness, main idea identification, summarisation, and questioning) for children with dyslexia. The second most common category of intervention was ‘Accessible learning environments’, for instance, programmes which aimed to improve social skills or to reduce rates of victimisation of children with disabilities in schools. Regarding intervention effects, included studies concerned with ‘Conditions for inclusion of people with disabilities in education’ showed a moderately significant effect, and one study concerned with teacher knowledge showed a significant effect size. Among the 18 studies included in the analysis of intervention effects on ‘Skills for learning’, 12 interventions had a significant effect. When considering the effect of interventions on different outcomes, we see that the effect on literacy, cognitive skills, handwriting, and numeracy are significant. All these effects are large but are based on a low number of studies. The studies concerned with speech and school behaviour show no significant effect of intervention. Across studies, heterogeneity is high, and risk of publication bias varies but was frequently high. All but one study received an overall rating of low confidence in study findings. However, this lack of confidence across studies was largely due to the use of low-rigour study designs and was not always reflective of multiple points of weakness within a given study. **Authors' Conclusions**: Children with disabilities fall behind in educational outcomes as the current school systems are not set up to teach children with different impairment types. There is no one ‘magic bullet’ intervention which can equalise health outcomes for this group. A twin-track approach is needed, which both addresses the specific needs of children with disabilities but also ensures that they are included in mainstream activities (e.g., through improving the skills of teachers and accessibility of the classroom). However, currently most interventions included in this systematic review targeted individual children with disabilities in an attempt to improve their functioning, skills, and competencies, but did not focus on mainstreaming these children into the school by system-level or school-level changes. Consequently, a focus on evaluation of interventions which target not just the individual with a disability but also their broader environment, are needed.
AU  - Hunt,
AU  - X.,
AU  - Saran,
AU  - A.,
AU  - White,
AU  - H.,
AU  - Kuper,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1002/cl2.70016
PY  - 2025
T2  - Campbell Systematic Reviews
TI  - Effectiveness of interventions for improving educational outcomes for people with disabilities in low- and middle-income countries: A systematic review
ER  -
TY  - JOUR
AB  - Generative artificial intelligence (GAI) has brought new ideas for optimizing students' learning. Despite increasing attention on the effects of GAI on learning outcomes (LO), research results are inconsistent. While GAI's educational benefits are qualitatively described, there is substantial debate about its actual impact on students' LO. The study sought to quantify GAI's impact on students' LO, evaluating its overall and average effects, and examining four key moderating factors: functional types of GAI, educational levels, intervention duration, and knowledge domains. Based on the screening criteria, 26 empirical studies were selected from 5,887 peer-reviewed papers. Two researchers collaboratively completed the literature screening and coding process. The research employed a meta-analytic method to calculate the impact of GAI on learners' LO, and examined four moderating factors. GAI exerts a significant but small overall effect on students' LO (g = 0.392), with varying impacts on physical (g = 0.701), social-emotional (g = 0.347), and intellectual (g = 0.372) outcomes. The changes of GAI's functional types have no significant effect on LO, but three other moderating factors do, showing significant statistical differences. GAI more significantly impacts primary school students, especially in supporting their intellectual and social-emotional outcomes. Longer interventions have a greater effect on LO than short ones, particularly intellectual and physical outcomes. GAI's effects vary across knowledge domains, possibly due to its adaptability in different subjects. Long-term GAI in higher education boosts intellectual and physical outcomes, especially in education and humanities and arts, while short-term use in primary education enhances social-emotional outcomes. Integrating diverse learning components and adjusting GAI implementation parameters can optimize its effectiveness in terms of enhancing LO across different levels of education.
AN  - WOS:001432408400001
AU  - Zhu,
AU  - Y.
AU  - K.
AU  - Liu,
AU  - Q.
AU  - W.
AU  - Zhao,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - 10.1007/s10639-025-13420-z
L1  - internal-pdf://3904395309/Zhu-2025-Exploring the impact of generative ar.pdf
PY  - 2025
SP  - 29
T2  - Education and Information Technologies
TI  - Exploring the impact of generative artificial intelligence on students' learning outcomes: a meta-analysis
UR  - <Go to ISI>://WOS:001432408400001
UR  - https://link.springer.com/article/10.1007/s10639-025-13420-z
UR  - https://link.springer.com/content/pdf/10.1007/s10639-025-13420-z.pdf
ER  -
TY  - JOUR
AB  - As a leading cause of adolescent death, suicidal and self-injurious related behaviors (SSIRBs) is a devastating global health problem, particularly among patients with psychiatric disorders (PDs). Previous studies have shown that multiple interventions can alleviate symptoms and reduce risks. This review aimed to provide a systematic summary of interventions (i.e., medication, physical therapy, psychosocial therapy) for the treatment of SSIRBs among Chinese adolescents with PDs. From inception to September 17, 2023, twelve databases (PubMed, CINAHL, ScienceDirect, PsycINFO, EMBASE, Cochrane Library, Clinical Trial, Web of Science, CEPS, SinoMed, Wanfang and CNKI) were searched. We qualitatively and quantitatively synthesized the included studies. Standardized mean differences (SMDs), risk ratios and their 95% confidence intervals (CIs) used the Der Simonian and Laird random-effects model. Fifty-two studies covering 3709 eligible participants were included. Overall, the commonly used interventions targeting SSIRBs and negative feelings in PDs adolescents with SSIRBs included psychosocial therapy (e.g., cognitive behavioral therapy), medication (e.g., antidepressants), and physiotherapy (e.g., repetitive transcranial magnetic stimulation). Importantly, quetiapine fumarate in combination with sodium valproate (SV) had positive effects on reducing self-injury behaviors score [SMD: -2.466 (95% CI: -3.305, -1.628), I<sup>2</sup> = 88.36%], depression [SMD: -1.587 (95% CI: -2.505, -0.670), I<sup>2</sup> = 90.45%], anxiety [SMD: -1.925 (95% CI: -2.700, -1.150), I<sup>2</sup> = 85.23%], impulsivity [SMD: -2.439 (95% CI: -2.748, -2.094), I<sup>2</sup> = 0%], as well as its safety in comparison with SV alone. No significant difference of adverse reactions was found by low-dose QF (P > 0.05). This review systematically outlined the primary characteristics, safety and effectiveness of interventions for Chinese PDs adolescents with SSIRBs, which could serve as valuable evidence for guidelines aiming to formulate recommendations.
AN  - 40044640
AU  - Lu,
AU  - J.
AU  - Huang,
AU  - J.
AU  - Gao,
AU  - W.
AU  - Wang,
AU  - Z.
AU  - Yang,
AU  - N.
AU  - Luo,
AU  - Y.
AU  - Guo,
AU  - J.
AU  - Pang,
AU  - W.
AU  - I.
AU  - P.
AU  - Lok,
AU  - G.
AU  - K.
AU  - I.
AU  - Rao,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1038/s41398-025-03278-7
L1  - internal-pdf://0125786298/Lu-2025-Interventions for suicidal and self-in.pdf
PY  - 2025
SP  - 73
T2  - Translational Psychiatry
TI  - Interventions for suicidal and self-injurious related behaviors in adolescents with psychiatric disorders: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1038%2fs41398-025-03278-7
UR  - https://www.nature.com/articles/s41398-025-03278-7.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - **Background**: Childhood obesity and mental health disorders are increasingly prevalent. While lifestyle interventions are widely recognized as effective for managing obesity in children and adolescents, their effects on mental health remain unclear. This study aimed to systematically evaluate the effects of lifestyle interventions on mental health outcomes among children and adolescents with overweight or obesity. **Methods**: In this systematic review and meta-analysis, we searched five databases (PubMed, Embase, MEDLINE, CENTRAL and CINAHL) for relevant randomised controlled trials (RCTs) or non-randomised studies of interventions (NRSIs) published from database inception to December 7, 2024, without language restrictions. Lifestyle interventions are defined as structured programs that promote health-related behavioural changes across diverse domains, such as physical activity, dietary adjustments, cognitive training, and psychosocial support. We included studies that assessed the effects of lifestyle interventions on mental health outcomes among children and adolescents with overweight or obesity. Two reviewers independently screened records for eligibility, extracted study-level data and assessed risk of bias of RCTs and NRSIs via the revised Cochrane Risk of Bias Tool for randomised controlled trials (RoB 2) and the Risk of Bias in Non-randomised Studies-of Interventions (ROBINS-I), and certainty of the evidence by the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. RCTs were prioritized as the primary source of evidence, while NRSIs served as supplementary evidence. A random-effects meta-analysis model was performed to calculate pooled standardized mean differences (SMDs) and 95% confidence intervals (CIs). Subgroup analyses stratified by age, body mass index (BMI) category, intervention type, theoretical framework, duration, and World Bank income region, were further conducted to identify potential sources of heterogeneity. The review protocol was registered in PROSPERO, CRD42024571061. **Findings**: We identified 20,359 records, of which 26 studies (17 RCTs and nine NRSIs) involving 3511 children and adolescents with overweight or obesity were included. Mental health outcomes assessed included depression, anxiety, self-concept, self-efficacy, negative affect, quality of life, and emotional functioning. Lifestyle interventions evaluated encompassed physical activity, health education, emotion regulation, diet, and multicomponent approaches. Among RCTs, reductions in depression (SMD = -0.24, 95% CI: -0.39 to -0.10, I-square [I <sup>2</sup>] = 0.0%) and improvements in quality of life (SMD = 0.24, 95% CI: 0.04-0.44, I <sup>2</sup> = 44.0%) were observed, with moderate certainty. Subgroup analyses revealed greater reductions in depression among adolescents and participants with obesity, in programs that involving multicomponent approaches, lasting below three months, using behavioural and cognitive theory, or being conducted in high-income countries (HICs). For quality of life, greater improvements were observed among participants with overweight or obesity, in programs based on behavioural and cognitive theory, or in those conducted in low- and middle-income countries (LMICs). Meanwhile, among NRSIs, reductions in depression (SMD = -0.22, 95% CI: -0.33 to -0.11, I <sup>2</sup> = 11.5%), as well as enhancements in self-concept (SMD = 0.19, 95% CI: 0.09-0.29, I <sup>2</sup> = 0.0%), quality of life (SMD = 0.52, 95% CI: 0.23-0.81, I <sup>2</sup> = 86.2%), and emotional functioning (SMD = 0.40, 95% CI: 0.21-0.60, I <sup>2</sup> = 0.0%) were noted. However, the effects on other mental health outcomes, including anxiety, negative affect, and self-efficacy, remain inconclusive. **Interpretation**: Lifestyle interventions modestly improve depressive symptoms and quality of life in children and adolescents with overweight or obesity, with additional benefits for self-concept and emotional functioning observed in NRSIs. These findings underscore the potential of lifestyle interventions to address both physical and mental health. Future research should focus on evaluating long-term psychological outcomes and developing cost-effective, culturally tailored interventions. **Funding**: This study was supported by National Natural Science Foundation of China (72474196).
AN  - 40093991
AU  - Zhou,
AU  - J.
AU  - Song,
AU  - Y.
AU  - Ying,
AU  - J.
AU  - Zhang,
AU  - C.
AU  - Wu,
AU  - J.
AU  - Shan,
AU  - S.
AU  - Zha,
AU  - J.
AU  - Zhou,
AU  - L.
AU  - Xiao,
AU  - W.
AU  - Song,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted Copy.enl
DO  - /10.1016/j.eclinm.2025.103121
L1  - internal-pdf://1487624237/Zhou-2025-Effects of lifestyle interventions o.pdf
PY  - 2025
SP  - 103121
T2  - Eclinicalmedicine
TI  - Effects of lifestyle interventions on mental health in children and adolescents with overweight or obesity: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.1016%2fj.eclinm.2025.103121
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11906288/pdf/main.pdf
VL  - 81
ER  -
TY  - JOUR
AB  - Pharmacological treatments (i.e., melatonin) and non-pharmacological therapies (e.g., parent-based sleep education programs and behavioural interventions) have been found to result in improved sleep in children and adolescents with autism spectrum disorder (ASD). However, there are several limitations to these treatment approaches, including concerns about the possible side-effects and safety, high-cost and uncertainties of long-term effects. Physical activity (PA) intervention is a promising behavioural intervention that has received increasing attention. However, the effects of PA intervention on sleep are still unclear in this clinical group. This study aimed to synthesize available empirical studies concerning the effects of PA interventions on sleep in children and adolescents with ASD. Following PRISMA guidelines, seven electronic databases: APA PsychInfo, CINAHL Ultimate, ERIC, MEDLINE, PubMed, SPORTDiscus, and Web of Science, were searched from inception to March 2023. Randomized controlled trials/quasi-experimental designs with comparison groups were included. Initially, 444 articles were identified, 13 articles underwent systematic review, and 8 studies with control groups and sufficient statistical data were selected for meta-analysis. Compared to no-treatment control groups, PA interventions had a large positive effect on parent-reported general sleep problems, night awakenings, sleep resistance, sleep duration and actigraphy-assessed sleep efficiency in children and adolescents with ASD.
AN  - 38442500
AU  - Liang,
AU  - X.
AU  - Haegele,
AU  - J.
AU  - A.
AU  - Tse,
AU  - A.
AU  - C.
AU  - Li,
AU  - M.
AU  - Zhang,
AU  - H.
AU  - Zhao,
AU  - S.
AU  - Li,
AU  - S.
AU  - X.
DB  - Mars 24.enl
DO  - /10.1016/j.smrv.2024.101913
L1  - internal-pdf://1859438016/1-s2.0-S1087079224000170-main.pdf
PY  - 2024
SP  - 101913
T2  - Sleep Medicine Reviews
TI  - The impact of the physical activity intervention on sleep in children and adolescents with autism spectrum disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1016%2fj.smrv.2024.101913
UR  - https://www.sciencedirect.com/science/article/pii/S1087079224000170?via%3Dihub
VL  - 74
ER  -
TY  - JOUR
AB  - BACKGROUND: Systemic therapy (ST) is a psychotherapeutic intervention in complex human systems (both psychological and interpersonal). Cognitive behavioural therapy (CBT) is an established treatment for children and adolescents with mental disorders. As methodologically rigorous systematic reviews on ST in this population are lacking, we conducted a systematic review and meta-analysis to compare the benefit and harm of ST (and ST as an add-on to CBT) with CBT in children and adolescents with mental disorders. 

METHODS: We searched MEDLINE, Embase, PsycINFO and other sources for randomised controlled trials in 14 mental disorder classes for the above comparisons in respect of effects on patient-relevant outcomes (search date: 7/2022). Where possible, meta-analyses were performed and results were graded into 3 different evidence categories: "proof", "indication", or "hint" (or none of these categories). PRISMA standards were followed. 

RESULTS: Fifteen studies in 5 mental disorder classes with usable data were identified. 2079 patients (mean age: 10 to 19 years) were analysed. 12/15 studies and 29/30 outcomes showed a high risk of bias. In 2 classes, statistically significant and clinically relevant effects in favour of ST were found, supporting the conclusion of a hint of greater benefit of ST for mental and behavioural disorders due to psychoactive substance use and of ST as an add-on to CBT for obsessive-compulsive disorders. In 2 other classes (eating disorders; hyperkinetic disorders), there was no evidence of greater benefit or harm of ST. For affective disorders, a statistically significant effect to the disadvantage of ST was found for 1 outcome, supporting the conclusion of a hint of lesser benefit of ST. 

CONCLUSIONS: Our results show a hint of greater benefit of ST (or ST as an add-on to CBT) compared with CBT for 2 mental disorder classes in children and adolescents (mental and behavioural disorders due to psychoactive substance use, obsessive compulsive disorders). Given the importance of CBT as a control intervention, ST can therefore be considered a beneficial treatment option for children and adolescents with certain mental disorders. Limitations include an overall high risk of bias of studies and outcomes and a lack of data for several disorders.
AN  - 38355466
AU  - Seidel,
AU  - D.
AU  - H.
AU  - Markes,
AU  - M.
AU  - Grouven,
AU  - U.
AU  - Messow,
AU  - C.
AU  - M.
AU  - Sieben,
AU  - W.
AU  - Knelangen,
AU  - M.
AU  - Oelkers-Ax,
AU  - R.
AU  - Grumer,
AU  - S.
AU  - Kolsch,
AU  - H.
AU  - Kromp,
AU  - M.
AU  - von
AU  - Pluto
AU  - Prondzinski,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1186/s12888-024-05556-y
L1  - internal-pdf://2097107059/Seidel-2024-Systemic therapy in children and a.pdf
PY  - 2024
SP  - 125
T2  - BMC Psychiatry
TI  - Systemic therapy in children and adolescents with mental disorders: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&AN=38355466
UR  - https://bmcpsychiatry.biomedcentral.com/counter/pdf/10.1186/s12888-024-05556-y.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - Online parenting programs to support parents of children with behavioral problems and emotional problems have become widely available in recent years. Research has consistently shown their positive effects on child development, parents' adaptive parenting practices, and parents' mental health. However, knowledge is lacking on which type of content is more suitable to be delivered online. Our work addresses this knowledge gap by conducting traditional and network meta-analyses to improve our understanding of (1) how effective online parenting programs are to improve children's behavior and emotional problems, and (2) what clusters of components are most likely to yield the strongest effects. Following the PROSPERO preregistration, we systematically searched PsycINFO, MEDLINE, Web of Science, and Cochrane. Of the 8292 records retrieved, 28 records on 27 randomized controlled trials (N = 5,312) met the inclusion criteria. Results show moderate effect sizes of online parenting programs on reduced child behavioral and emotional problems, parents' ineffective parenting practices, and parents' mental health problems. Online programs adopting a learning theory perspective, either with or without additional parental self-care and parents as therapist approaches, are most likely to yield the strongest effects on child behavioral problems. Online programs adopting a learning theory perspective, parental self-care and parents as therapist approaches, with or without additional relationship perspectives, are most likely to yield the strongest effects on child emotional problems. Online parenting programs seem promising tools for improving child behavioral and emotional problems. Future research should identify the circumstances that allow parents and children to benefit more from specific components in these programs. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2025-36330-001
AU  - Canario,
AU  - Ana
AU  - Catarina
AU  - Pinto,
AU  - Rita
AU  - Silva-Martins,
AU  - Marco
AU  - Rienks,
AU  - Karen
AU  - Akik,
AU  - Burcu
AU  - Komurcu
AU  - Stanke,
AU  - Koraljka
AU  - Modic
AU  - David,
AU  - Oana
AU  - Kiziltepe,
AU  - Rukiye
AU  - Melendez-Torres,
AU  - G.
AU  - Thongseiratch,
AU  - Therdpong
AU  - Leijten,
AU  - Patty
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1007/s11121-024-01735-1
L1  - internal-pdf://3587174163/Canario-2024-Online parenting programs for chi.pdf
PY  - 2024
SP  - No Pagination Specified
T2  - Prevention Science
TI  - Online parenting programs for children's behavioral and emotional problems: A network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=psyc23&DO=10.1007%2fs11121-024-01735-1
UR  - https://link.springer.com/content/pdf/10.1007/s11121-024-01735-1.pdf
ER  -
TY  - JOUR
AB  - Peer-mediated interventions are interventions in which peers without disabilities are systematically taught to engage children with disabilities in positive social interactions, with the aim of helping children with disabilities acquire new, targeted social skills. Peer-mediated interventions have been used to enhance the social and play skills of young children with disabilities for many years and continues to be commonly used with young children with disabilities in classroom settings. Because of the frequent use of peer-mediated interventions, it is important to know the level of empirical support for this instructional practice. The objective of this overview was to evaluate systematic reviews of peer-mediated interventions for young children with or at risk for disabilities under the age of five years old.This synthesis is an overview of reviews, which is a review method used for evaluating existing research reviews. To complete this overview, we searched electronic databases and other sources for published articles presenting the results of reviews of studies on peer-mediated interventions for young children with or at risk for disabilities under the age of five years old. We then synthesized the findings across reviews to formulate conclusions on the effects of the intervention to make practice recommendations. We searched the literature in October 2023 for articles that presented findings of a systematic review on peer-mediated interventions for young children with or at risk of disabilities under the age of five years old. We located 10 reviews. In the 10 reviews there were 47 studies with 114 young children with a variety of developmental disabilities. In the studies included in the reviews, the peer-mediated interventions typically occurred in natural settings including inclusive classrooms and children's homes. The findings from all 10 included reviews suggested that peer-mediated interventions were an effective intervention for improving the social development of young children with disabilities. Over 80% of the 47 studies included in the 10 reviews had positive findings. Three reviews conducted a meta-analysis, which is a statistical technique of combining results across studies. All three meta-analyses showed robust results of the peer-mediated intervention. Thus, the use of peer-mediated interventions for children with or at risk of disabilities under the age of five is strongly supported by empirical research. Therefore, peer-mediated interventions should be considered an evidence-based practice for young children with disabilities. As demonstrated in the reviews, the use of peer-mediated interventions was most robust when used with preschool-aged children in inclusive (natural) settings.
AN  - WOS:001345969400001
AU  - Reichow,
AU  - B.
AU  - Song,
AU  - J.
AU  - W.
DB  - November 2024.enl
DO  - 10.1177/02711214241281383
L1  - internal-pdf://0240683179/Reichow-2024-Overview of Reviews of Peer-media.pdf
PY  - 2024
SP  - 15
T2  - Topics in Early Childhood Special Education
TI  - Overview of Reviews of Peer-mediated Interventions for Young Children With Disabilities
UR  - <Go to ISI>://WOS:001345969400001
UR  - https://journals.sagepub.com/doi/10.1177/02711214241281383
UR  - https://journals.sagepub.com/doi/pdf/10.1177/02711214241281383?download=true
ER  -
TY  - JOUR
AB  - Background
Surf therapy is gaining popularity for improving mental health. However, there is limited research evidence to substantiate these claims. Therefore, this systematic review aimed to assess randomized or non-randomized studies analyzing the efficacy of surf therapy in improving symptoms of mental illness compared to non-exercising controls and/or alternative intervention, and to identify evidential gaps to inform future research.

Methods
PRISMA 2020 reporting guidelines were followed. Eligibility criteria included participants of any age and sex, explicitly diagnosed with any mental health disorder, while exposed to surf therapy and compared to non-exercising controls and/or alternative interventions. The primary outcome consisted of changes in symptoms of mental illness scored from baseline to post-intervention. Any randomized or non-randomized trial design was considered. We searched Cochrane Library, CINAHL, EMBASE, PubMed, Scopus, SPORTDiscus and Web of Science databases (December 7, 2023), without language or publication date restrictions and without filters. Risk of bias was assessed using RoB 2. A meta-analysis could not be conducted due to heterogeneity of the studies; therefore, a narrative synthesis of individual study results was performed.

Results
Of 5,666 records, three randomized controlled studies were included in the review. Overall, the findings of the three studies suggest no robust consistent evidence of improvement in mental health symptoms when comparing surf therapy to wait-list control groups or other nature-based exercise interventions (hike therapy). Certainty of evidence should be considered very low, as it is based on three randomized controlled trials.

Conclusion
Although we believe that surf therapy provides an interesting approach, robust evidence is scarce. Routes for future well-designed, controlled studies are discussed.OtherNo funding to report. Registration: PROSPERO CRD42021277060.
AN  - WOS:001342166900001
AU  - Carneiro,
AU  - L.
AU  - Clemente,
AU  - F.
AU  - M.
AU  - Claudino,
AU  - J.
AU  - G.
AU  - Ferreira,
AU  - J.
AU  - Ramirez-Campillo,
AU  - R.
AU  - Afonso,
AU  - J.
DB  - November 2024.enl
DO  - 10.1186/s12906-024-04674-0
L1  - internal-pdf://0768836084/Carneiro-2024-Surf therapy for people with men.pdf
PY  - 2024
SP  - 10
T2  - Bmc Complementary Medicine and Therapies
TI  - Surf therapy for people with mental health disorders: a systematic review of randomized and non-randomized controlled trials
UR  - <Go to ISI>://WOS:001342166900001
UR  - https://bmccomplementmedtherapies.biomedcentral.com/counter/pdf/10.1186/s12906-024-04674-0.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - **Background:** 
Adolescence represents a distinctive phase of development, and variables linked to this developmental period could affect the efficiency of prevention and treatment for depression and anxiety, as well as the long-term prognosis. The objectives of this study were to investigate the long-term effectiveness of psychosocial interventions for adolescents on depression and anxiety symptoms and to assess the influence of different intervention parameters on the long-term effects. 

**Methods:** 
In this systematic review and meta-analysis, we searched five databases (Cochrane Library, Embase, Medline, PsychInfo, Web of Science) and trial registers for relevant papers published between database inception and Aug 11, 2022, with no restrictions on the language or region in which the study was conducted. An updated search was performed on Oct 3, 2023. Randomised controlled trials of psychosocial interventions targeting specifically adolescents were included if they assessed outcomes at 1-year post-intervention or more. The risk of bias in the results was assessed using the Cochrane RoB 2.0. Between-study heterogeneity was estimated using the I<sup>2</sup> statistic. The primary outcome was depression and studies were pooled using a standardised mean difference, with associated 95% confidence interval, p-value and I<sup>2</sup>. The study protocol was pre-registered on PROSPERO (CRD42022348668). 

**Findings:** 
57 reports (n = 46,678 participants) were included in the review. Psychosocial interventions led to small reductions in depressive symptoms, with standardised mean difference (SMD) at 1-year of -0.08 (95% CI: -0.20 to -0.03, p = 0.002, I<sup>2</sup> = 72%), 18-months SMD = -0.12, 95% CI: -0.22 to -0.01, p = 0.03, I<sup>2</sup> = 63%) and 2-years SMD = -0.12 (95% CI: -0.20 to -0.03, p = 0.01, I<sup>2</sup> = 68%). Sub-group analyses indicated that targeted interventions produced stronger effects, particularly when delivered by trained mental health professionals (K = 18, SMD = -0.24, 95% CI: -0.38 to -0.10, p = 0.001, I<sup>2</sup> = 60%). No effects were detected for anxiety at any assessment. 

**Interpretation:** 
Psychosocial interventions specifically targeting adolescents were shown to have small but positive effects on depression symptoms but not anxiety symptoms, which were sustained up to 2 years. These findings highlight the potential population-level preventive effects if such psychosocial interventions become widely implemented in accessible settings, such as schools. Future trials should include a longer term-follow-up at least at 12 months, in order to determine whether the intervention effects improve, stay the same or wear off over time. 
Funding: UKRI Medical Research Council.
AN  - 38273890
AU  - Duagi,
AU  - D.
AU  - Carter,
AU  - B.
AU  - Farrelly,
AU  - M.
AU  - Lisk,
AU  - S.
AU  - Shearer,
AU  - J.
AU  - Byford,
AU  - S.
AU  - James,
AU  - K.
AU  - Brown,
AU  - J.
AU  - S.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.eclinm.2023.102382
L1  - internal-pdf://1540716062/Duagi-2024-Long-term effects of psychosocial i.pdf
PY  - 2024
SP  - 102382
T2  - EClinicalMedicine
TI  - Long-term effects of psychosocial interventions for adolescents on depression and anxiety: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&AN=38273890
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10809118/pdf/main.pdf
VL  - 68
ER  -
TY  - JOUR
AB  - Self-injurious behavior (SIB) among children and youth with developmental disabilities has not diminished in prevalence despite the availability of effective interventions, and the impact on quality of life for people and their families is devastating. The current meta-analysis reviews SIB intervention research between 2011 and 2021 using single-case experimental designs with children and youth up to 21 years old and provides a quantitative synthesis of data from high-quality studies including moderator analyses to determine effects of participant and study characteristics on intervention outcomes. Encouraging findings include a high level of effectiveness across studies in the decrease of SIB (Tau-U = -0.90) and increase of positive behavior (Tau-U = 0.73), as well as an increase in studies (relative to prior reviews) reporting intervention fidelity, generalization, maintenance, and social validity. However, our findings shed limited light on potential moderating variables in the development of interventions for children and youth who exhibit SIB. Of the potential moderators of intervention effects, only implementer (researcher/therapist vs. parent/caregiver) and setting (clinic vs. home) were significantly associated with improved outcomes. We discuss the need for more robust involvement of natural communities of implementers in SIB intervention research to better equip them to effectively and sustainably meet the needs of people they care for. We also discuss the importance of creating systems enabling broad access for children with SIB to effective interventions in service of reducing burden for people, families, and society over time.
AN  - WOS:001140162800001
AU  - Moore,
AU  - T.
AU  - R.
AU  - Lee,
AU  - S.
AU  - H.
AU  - Freeman,
AU  - R.
AU  - Mahmoundi,
AU  - M.
AU  - Dimian,
AU  - A.
AU  - Riegelman,
AU  - A.
AU  - Simacek,
AU  - J.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/01454455231218742
L1  - internal-pdf://3979183456/moore-et-al-2024-a-meta-analysis-of-treatment-.pdf
PY  - 2024
SP  - 41
T2  - Behavior Modification
TI  - A Meta-Analysis of Treatment for Self-Injurious Behavior in Children and Adolescents With Intellectual and Developmental Disabilities
UR  - <Go to ISI>://WOS:001140162800001
UR  - https://journals.sagepub.com/doi/10.1177/01454455231218742
ER  -
TY  - JOUR
AB  - The experience of academic stress is common during high school and can have significant negative consequences for students' educational achievement and wellbeing. High school students frequently report heightened levels of school-related distress, particularly as they approach high-stakes assessments. Programs designed to reduce or prevent academic stress are needed, and their delivery in school settings is ideal to improve treatment access. The current review aimed to examine the effectiveness of high school-based programs in reducing or preventing academic stress. A systematic search returned 31 eligible studies across 13 countries. Programs were categorised according to intervention type, format, and facilitator. Results showed that the methodological quality of most studies was poor, and many used an inactive control group. As predicted by theories of academic stress, the strongest evidence was for programs grounded in cognitive-behavioural therapy (CBT). There was evidence that both universal and targeted approaches can be beneficial. The unique implementation issues for these two formats are discussed. Most programs were delivered by psychologists and were generally effective, but almost all of these were CBT programs. A smaller proportion of programs delivered by teachers were effective. Therefore, future studies should evaluate the implementation success of programs to improve the rate of effective delivery by school staff. Overall, the field will benefit from more randomised controlled trials with comparisons to active control groups, larger sample sizes and longer-term follow-ups.
AN  - 38436893
AU  - Jagiello,
AU  - T.
AU  - Belcher,
AU  - J.
AU  - Neelakandan,
AU  - A.
AU  - Boyd,
AU  - K.
AU  - Wuthrich,
AU  - V.
AU  - M.
DB  - Mars 24.enl
DO  - /10.1007/s10578-024-01667-5
L1  - internal-pdf://0093177483/Jagiello-2024-Academic Stress Interventions in.pdf
PY  - 2024
SP  - 04
T2  - Child Psychiatry & Human Development
TI  - Academic Stress Interventions in High Schools: A Systematic Literature Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs10578-024-01667-5
UR  - https://link.springer.com/content/pdf/10.1007/s10578-024-01667-5.pdf
VL  - 04
ER  -
TY  - JOUR
AB  - **Background**
Depression is a public health problem and common amongst adolescents. Cognitive behavioural therapy (CBT) is widely used to treat adolescent depression but existing research does not provide clear conclusions regarding the relative effectiveness of different delivery modalities.

**Objectives**
The primary aim is to estimate the relative efficacy of different modes of CBT delivery compared with each other and control conditions for reducing depressive symptoms in adolescents. The secondary aim is to compare the different modes of delivery with regard to intervention completion/attrition (a proxy for intervention acceptability).

**Search Methods**
The Cochrane Depression, Anxiety and Neurosis Clinical Trials Register was searched in April 2020. MEDLINE, PsycInfo, EMBASE, four other electronic databases, the CENTRAL trial registry, Google Scholar and Google were searched in November 2020, together with reference checking, citation searching and hand-searching of two databases.

**Selection Criteria**
Randomised controlled trials (RCTs) of CBT interventions (irrespective of delivery mode) to reduce symptoms of depression in young people aged 10–19 years with clinically relevant symptoms or diagnosis of depression were included.

**Data Collection and Analysis**
Screening and data extraction were completed by two authors independently, with discrepancies addressed by a third author. CBT interventions were categorised as follows: group CBT, individual CBT, remote CBT, guided self-help, and unguided self-help. Effect on depressive symptom score was estimated across validated self-report measures using Hedges' g standardised mean difference. Acceptability was estimated based on loss to follow-up as an odds ratio. Treatment rankings were developed using the surface under the cumulative ranking curve (SUCRA). Pairwise meta-analyses were conducted using random effects models where there were two or more head-to-head trials. Network analyses were conducted using random effects models.

**Main Results**
Sixty-eight studies were included in the review. The mean age of participants ranged from 10 to 19.5 years, and on average 60% of participants were female. The majority of studies were conducted in schools (28) or universities (6); other settings included primary care, clinical settings and the home. The number of CBT sessions ranged from 1 to 16, the frequency of delivery from once every 2 weeks to twice a week and the duration of each session from 20 min to 2 h. The risk of bias was low across all domains for 23 studies, 24 studies had some concerns and the remaining 21 were assessed to be at high risk of bias. Sixty-two RCTs (representing 6435 participants) were included in the pairwise and network meta-analyses for post-intervention depressive symptom score at post-intervention. All pre-specified treatment and control categories were represented by at least one RCT. Although most CBT approaches, except remote CBT, demonstrated superiority over no intervention, no approaches performed clearly better than or equivalent to another. The highest and lowest ranking interventions were guided self-help (SUCRA 83%) and unguided self-help (SUCRA 51%), respectively (very low certainty in treatment ranking). Nineteen RCTs (3260 participants) were included in the pairwise and network meta-analyses for 6 to 12 month follow-up depressive symptom score. Neither guided self-help nor remote CBT were evaluated in the RCTs for this time point. Effects were generally attenuated for 6- to 12-month outcomes compared to posttest. No interventions demonstrated superiority to no intervention, although unguided self-help and group CBT both demonstrated superiority compared to TAU. No CBT approach demonstrated clear superiority over another. The highest and lowest ranking approaches were unguided self-help and individual CBT, respectively. Sixty-two RCTs (7347 participants) were included in the pairwise and network meta-analyses for intervention acceptability. All pre-specified treatment and control categories were represented by at least one RCT. Although point estimates tended to favour no intervention, no active treatments were clearly inferior. No CBT approach demonstrated clear superiority over another. The highest and lowest ranking active interventions were individual CBT and group CBT respectively. Pairwise meta-analytic findings were similar to those of the network meta-analysis for all analyses. There may be age-based subgroup effects on post-intervention depressive symptoms. Using the no intervention control group as the reference, the magnitudes of effects appear to be larger for the oldest age categories compared to the other subgroups for each given comparison. However, they were generally less precise and formal testing only indicated a significant difference for group CBT. Findings were robust to pre-specified sensitivity analyses separating out the type of placebo and excluding cluster-RCTs, as well as an additional analysis excluding studies where we had imputed standard deviations.

**Authors' Conclusions**
At posttreatment, all active treatments (group CBT, individual CBT, guided self-help, and unguided self-help) except for remote CBT were more effective than no treatment. Guided self-help was the most highly ranked intervention but only evaluated in trials with the oldest adolescents (16–19 years). Moreover, the studies of guided self-help vary in the type and amount of therapist support provided and longer-term results are needed to determine whether effects persist. The magnitude of effects was generally attenuated for 6- to 12-month outcomes. Although unguided self-help was the lowest-ranked active intervention at post-intervention, it was the highest ranked at follow-up. This suggests the need for further research into whether interventions with self-directed elements enable young people to maintain effects by continuing or revisiting the intervention independently, and whether therapist support would improve long-term outcomes. There was no clear evidence that any active treatments were more acceptable to participants than any others. The relative effectiveness of intervention delivery modes must be taken into account in the context of the needs and preferences of individual young people, particularly as the differences between effect sizes were relatively small. Further research into the type and amount of therapist support that is most acceptable to young people and most cost-effective would be particularly useful.
AU  - Bjornstad,
AU  - G.,
AU  - Sonthalia,
AU  - S.,
AU  - Rouse,
AU  - B.,
AU  - Freeman,
AU  - L.,
AU  - Hessami,
AU  - N.,
AU  - Dunne,
AU  - J.
AU  - H.,
AU  - Axford,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1002/cl2.1376
L1  - internal-pdf://2612330763/Campbell Systematic Reviews - 2024 - Bjornstad.pdf
PY  - 2024
T2  - Campbell Systematic Reviews
TI  - A comparison of the effectiveness of cognitive behavioural interventions based on delivery features for elevated symptoms of depression in adolescents: A systematic review
ER  -
TY  - JOUR
AB  - Natural disasters and extreme weather events have increased in recent years and are likely to increase further in the face of climate change. Many survivors of such events suffer from mental health complaints. We conducted a systematic review and meta-analysis on treatment efficacy of psychological interventions for mental disorders in survivors of natural disasters. Systematic database searches resulted in the inclusion of ten randomised controlled trials with 613 participants (37.8 % women). Nine of these trials focused on posttraumatic stress disorder (PTSD), whereas one trial included individuals with alcohol dependence. Studies were conducted in China, Turkey, Iran, Pakistan, and Thailand. Four trials included children and adolescents who received group treatments, whereas six trials included adults who received individual treatments. Most interventions consisted of cognitivebehavioural therapy (k = 7). Results suggest a significant short-term efficacy of interventions for PTSD compared to passive control conditions (g = 1.44; 95 % CI 0.53-2.35, k = 7). The long-term efficacy after an average of 8 weeks post-treatment remained significant (g = 0.59; 95 % CI 0.25-0.93, k = 4). The trials furthermore yielded significant treatment effects regarding comorbid depression compared to control conditions for both short-term and long-term assessments. Heterogeneity in effect sizes between individual studies was small to moderate. Our findings suggest that psychological interventions, especially cognitive-behavioural therapy, can effectively treat PTSD and comorbid mental health problems in survivors of natural disasters. Nonetheless, conclusions are limited by the small number of trials and the strong focus on PTSD.
AN  - WOS:001355144100001
AU  - Kip,
AU  - A.
AU  - Brouër,
AU  - P.
AU  - Morina,
AU  - N.
DB  - November 2024.enl
DO  - 10.1016/j.cresp.2024.100197
L1  - internal-pdf://1783527628/1-s2.0-S2666622724000182-main.cleaned.pdf
PY  - 2024
SP  - 9
T2  - Current Research in Ecological and Social Psychology
TI  - A meta-analysis on treatment efficacy of psychological interventions for mental disorders in individuals exposed to natural disasters
UR  - <Go to ISI>://WOS:001355144100001
UR  - https://www.sciencedirect.com/science/article/pii/S2666622724000182?pes=vor&utm_source=clarivate&getft_integrator=clarivate
VL  - 6
ER  -
TY  - JOUR
AB  - The current study aimed to conduct a systematic review and meta-analysis of self-management interventions for teaching daily living skills to autistic individuals. This study accessed the corresponding studies by doing a search in six databases. 14 articles and one dissertation met the inclusion criteria. The included studies were first analyzed descriptively and coded according to quality indicators using What Works Clearinghouse (WWC) standards. Second, the effect sizes of the included studies were calculated using two different effect size measures (i.e., Tau-U and performance-criteria-based effect size values [PCES]). Third, these analyses were also conducted for generalization and maintenance data. Of 15 studies included in this review, nine met the WWC standards with and without reservations. Tau-U analyses were conducted for 14 studies, whereas PCES values were calculated for only eight studies with mastery criteria. The findings indicated that the self-management interventions had a .93 CI95 (.80, 1) overall effect size for Tau-U with a very large effect. On the other hand, the overall effect size for the PCES values indicated a moderate effect with .99. The weighted effect sizes in generalization and maintenance phases were very large for Tau-U; however, moderate to high effects for PCES. Although self-management interventions showed diversity, one of the domains of daily living skills (i.e., community living skills) has not been studied in the field. Notably, among the studies in our review, the last ones are from 2019. Detailed findings from descriptive analyses and two different effect size calculations are discussed, and recommendations for future studies are given.
AN  - WOS:001216112700001
AU  - Aydin,
AU  - O.
AU  - Sulu,
AU  - M.
AU  - D.
AU  - Ari-Arat,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1007/s10803-024-06355-w
L1  - internal-pdf://1699371212/Aydin-2024-A Meta-Analysis of Self-Management.pdf
PY  - 2024
SP  - 16
T2  - Journal of Autism and Developmental Disorders
TI  - A Meta-Analysis of Self-Management Interventions in Teaching Daily Living Skills to Autistic Individuals
UR  - <Go to ISI>://WOS:001216112700001
UR  - https://link.springer.com/content/pdf/10.1007/s10803-024-06355-w.pdf
ER  -
TY  - JOUR
AB  - Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with executive function deficits that are improved with medications. However, meta-analyses of stimulant effects on cognition have mostly tested single-dose effects, and there is no meta-analysis of non-stimulant effects. This systematic review and meta-analysis tested the clinically more relevant longer-term effects of Methylphenidate (20 studies; minimum 1 week) and Atomoxetine (8 studies; minimum 3 weeks) on reaction time, attention, inhibition, and working memory, searching papers on PubMed, Embase, Ovid MEDLINE, and PsycINFO. The meta-analysis of 18 studies in 1667 subjects showed that methylphenidate was superior to placebo in all cognitive domains with small to medium effect sizes (Hedges g of 0.34-0.59). The meta-analysis of atomoxetine included 7 studies in 829 subjects and showed no effects in working memory, but superior effects in the other domains with medium to large effect sizes (Hedge's g of 0.36-0.64). Meta-regression analysis showed no drug differences on cognitive effects. The meta-analyses show for the first time that chronic Methylphenidate and Atomoxetine have comparable effects of improving executive functions in people with ADHD.
AN  - WOS:001240360600001
AU  - Isfandnia,
AU  - F.
AU  - El
AU  - Masri,
AU  - S.
AU  - Radua,
AU  - J.
AU  - Rubia,
AU  - K.
DB  - Juni 24.enl
DO  - 10.1016/j.neubiorev.2024.105703
L1  - internal-pdf://0092039786/1-s2.0-S0149763424001726-main.cleaned.pdf
PY  - 2024
SP  - 23
T2  - Neuroscience and Biobehavioral Reviews
TI  - The effects of chronic administration of stimulant and non-stimulant medications on executive functions in ADHD: A systematic review and meta-analysis
UR  - <Go to ISI>://WOS:001240360600001
VL  - 162
ER  -
TY  - JOUR
AB  - **Introduction**
The aim of this study is to assess the effectiveness of serotonin-norepinephrine reuptake inhibitors (SNRIs) in managing ADHD symptoms compared to placebo, stimulants, or compared as pre- and post-treatment.

**Methods**
Clinical trials assessing the potency of SNRIs in treating ADHD patients were imported from PubMed, Web of Science, and Scopus (until February 2023). Data were extracted by two independent researchers. Random- and fixed- effect meta-analysis was performed to pool the data. Publication bias and study heterogeneity were assessed. The Cochrane Collaboration tool was utilized to determine the risk of bias. The certainty of outcomes was evaluated by the Grade criteria.

**Results**
Of the initial 830 studies, 13 were finally imported after two screening stages which two separate researchers carried out. The pooled standardized mean difference (95% CI) of reducing the score of different ADHD questionnaires (showing reduction in total inattentive and hyperactivity/impulsivity symptoms) by SNRIs, venlafaxine, and duloxetine were - 2.20 [- 3.00, - 1.40], - 1.86 [- 2.69, - 1.02], - 2.65 [- 3.35, - 1.96], respectively. While the most reported side effects were nausea, abdominal pain, and sedation, all studies reported that side effects were not serious and were well tolerated. Outcomes for the effectiveness of venlafaxine and duloxetine got high and moderate certainty, respectively.

**Conclusions**
Duloxetine and venlafaxine can be administered to treat symptoms of ADHD while being well tolerated. It seems that duloxetine is more potent in reducing ADHD symptoms. It can also be concluded that venlafaxine is more effective in females, and is more effective on inattentive symptoms of ADHD rather than hyperactive symptoms.
AN  - WOS:001150911500001
AU  - Dezfouli,
AU  - R.
AU  - A.
AU  - Hosseinpour,
AU  - A.
AU  - Ketabforoush,
AU  - S.
AU  - Daneshzad,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1186/s43045-024-00400-1
L1  - internal-pdf://3256096766/Dezfouli-2024-Efficacy, safety, and tolerabili.pdf
PY  - 2024
SP  - 26
T2  - Middle East Current Psychiatry-Mecpsych
TI  - Efficacy, safety, and tolerability of serotonin-norepinephrine reuptake inhibitors in controlling ADHD symptoms: a systematic review and meta-analysis
UR  - <Go to ISI>://WOS:001150911500001
UR  - https://mecp.springeropen.com/counter/pdf/10.1186/s43045-024-00400-1.pdf
VL  - 31
ER  -
TY  - JOUR
AB  - PURPOSE: This study was aimed to review and analyze the evidence of the psychosocial interventions for survivors of childhood cancer. 

METHODS: Electronic databases (PubMed, Embase, Medline, Web of Science, Science Direct, and Scopus) and manuel search were performed for psychosocial randomised controlled trials (RCTs) conducted with survivors who were diagnosed under the age of 18 and have completed treatment. Meta-analyses were performed to evaluate the effects of interventions on psychosocial health outcomes. The trials were published in English between 1 January 2000 to 30 June 2022 were included. Extracted data were analyzed using Review Manager 5.4. 

RESULTS: Ten trials conducted with 955 childhood cancer survivors were included in the systematic review. Meta-analysis of six RCTs showed no difference in the general quality of life (SMD, 0.07; 95% CI: [-0.09 to 0.23], I<sup>2</sup> 0%, (p > 0.05)) and three RCTs showed no difference in the physical activity self-efficacy (SMD, 0.12; 95% CI: [-0.35 to 0.58], I<sup>2</sup> 75%, (p > 0.05)) between intervention and control group. Interventions longer than 24 weeks (including follow-up) were effective in the quality of life and physical activity self-efficacy of the survivors. The overall quality of the evidence was low due to overall low risk of bias for only half of the studies (50%). 

CONCLUSIONS: Psychosocial interventions were not effective on quality of life and physical activity self-efficacy of childhood cancer survivors, however, long-term interventions provided improvement in these outcomes. 

REGISTRATION: The protocol for the meta-analysis was registered at PROSPERO (CRD42022375053/22 Nov 2022).
AN  - 38460392
AU  - Arpaci,
AU  - T.
AU  - Altay,
AU  - N.
DB  - Mars 24.enl
DO  - /10.1016/j.ejon.2024.102541
L1  - internal-pdf://0827967052/1-s2.0-S1462388924000395-main.cleaned.pdf
PY  - 2024
SP  - 102541
T2  - European Journal of Oncology Nursing
TI  - Psychosocial interventions for childhood cancer survivors: Systematic review and meta-analysis of randomized control trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1016%2fj.ejon.2024.102541
UR  - https://www.sciencedirect.com/science/article/pii/S1462388924000395?via%3Dihub
VL  - 69
ER  -
TY  - JOUR
AB  - Background: The efficacy of bumetanide on autism spectrum disorders (ASD) has been extensively studied, but the results remain inconclusive, necessitating a critical examination to determine its therapeutic role. Therefore, this study conducted a meta-analysis of bumetanide treatments for ASD to explore its efficacy and identify subpopulation that responded positively. 

Methods: A systematic search was conducted on PubMed, EMBASE, MEDLINE, PsyclNFO, Web of Science, Clinical Trials.gov, and references in reviews from the earliest available date to September 2023. Randomized controlled trials (RCTs) were identified that evaluated the efficacy of bumetanide in improving overall core symptoms (OCS) of ASD. Therefore, nine studies with 1036 participants were included in the study. 

Results: Bumetanide showed significant effects on OCS of ASD (WMD = - 1.91, p = 0.006), particularly in sub-domains including relation to inanimate objects, adaption to environment changes, auditory response, near sensory responses, anxiety and hyperactivity. Moderating analysis indicated that a significant effect size of bumetanide on OCS of ASD was observed in specific subgroup, including 3-6 years old (WMD = -1.08, p = 0.008), the tablet (WMD = 2.80, p = 0.003), 3-month intervention (WMD = -2.54, p = 0.003), and the single-center studies (WMD = -2.80, p = 0.003). 

Conclusions: Bumetanide has a large and significant impact on the OCS of ASD. Given the limited number and quality of included RCTs, future research should prioritize conducting large-scale trials focusing on sub-parameters or specific clinical features to comprehensively evaluate the efficacy of bumetanide in subpopulations of children with ASD.
AN  - WOS:001220755200001
AU  - Xiao,
AU  - H.
AU  - L.
AU  - Zhu,
AU  - H.
AU  - Jing,
AU  - J.
AU  - Q.
AU  - Jia,
AU  - S.
AU  - J.
AU  - Yu,
AU  - S.
AU  - H.
AU  - Yang,
AU  - C.
AU  - J.
DB  - Juni 24.enl
DO  - 10.1016/j.rasd.2024.102363
L1  - internal-pdf://2935450593/1-s2.0-S1750946724000382-main.cleaned.pdf
PY  - 2024
SP  - 13
T2  - Research in Autism Spectrum Disorders
TI  - Can bumetanide be a miraculous medicine for autism spectrum disorder: Meta-analysis evidence from randomized controlled trials
UR  - <Go to ISI>://WOS:001220755200001
VL  - 114
ER  -
TY  - JOUR
AB  - **AIM**: The aim of this study was to evaluate the efficacy of Group social skills interventions (GSSIs) versus any comparator on social functioning in children aged 5-12 years with acquired brain injury or cerebral palsy. 

**BACKGROUND**: GSSIs are an evidence-based approach to foster social skills development in children with autism spectrum disorder. Currently, limited literature exploring GSSIs in children with acquired brain injury and cerebral palsy is available. 

**RESULTS**: MEDLINE, SCOPUS, Embase, CINAHL, Cochrane Library, PsycINFO, clinicaltrials.gov, ICTRP and ProQuest Dissertations and Theses were systematically searched. Study screening, risk-of-bias, Grading of Recommendations Assessment, Development and Evaluation and data extraction were performed in duplicate. Six studies were included in the narrative synthesis (one randomised controlled trial and five nonrandomised studies). Results indicate that GSSIs may increase children's social skills as measured on the Social Skills Rating System and Social Skills Questionnaire. Very low certainty evidence was found for improvements in social functioning and competence. 

**CONCLUSIONS**: There is low certainty evidence that participation in GSSI may lead to gains in social functioning for children with acquired brain injury or cerebral palsy. Given the certainty of the evidence, these results must be interpreted with caution. Only one randomised controlled trial of GSSIs for children with acquired brain injury was identified, underscoring the need for additional high-quality studies.
AN  - 38528324
AU  - Thompson,
AU  - B.
AU  - A.
AU  - D.
AU  - Gilmore,
AU  - R.
AU  - Barfoot,
AU  - J.
AU  - Sakzewski,
AU  - L.
DB  - Mars 24.enl
DO  - /10.1111/cch.13242
L1  - internal-pdf://1574159917/Thompson-2024-A systematic review of the effic.pdf
PY  - 2024
SP  - e13242
T2  - Child: Care, Health & Development
TI  - A systematic review of the efficacy of group social skills interventions on social functioning and social participation in children with acquired brain injury or cerebral palsy
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1111%2fcch.13242
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cch.13242?download=true
VL  - 50
ER  -
TY  - JOUR
AB  - Background
Mental health disorders including major depressive disorder (MDD) are well recognized as major contributors to the global burden of disease among adolescents. The prevalence of adolescent depression is estimated to have increased by at least 25% during the COVID‐19 pandemic, compounding the already challenging problem of insufficient mental health service and service accessibility that existed prepandemic.

Omega‐3 polyunsaturated fatty acid (PUFA) supplementation is currently recommended as a preventive treatment for depression in high‐risk adults as well as a second‐line monotherapy for adults with mild to moderate MDD, and adjunctive to antidepressants for adults with moderate to severe MDD. The benefits of omega‐3 PUFA intake on depressive illness have been hypothesized to occur as a result of their effect on neurotransmission, maintenance of membrane fluidity, and anti‐inflammatory action. A comprehensive synthesis and quantification of the existing evidence on omega‐3 PUFA's efficacy in treating depression among children and adolescents is essential for clinicians to provide informed guidance to young people and their families, especially considering the absence of current guidelines for this age group.

Objectives
Primary objective

To determine the impact of omega‐3 PUFA supplementation versus a comparator (e.g. placebo, wait list controls, no treatment/supplementation, or standard care) on clinician‐diagnosed depression or self‐reported depression symptoms in children and adolescents.

Secondary objectives

To estimate the size of the effect of omega‐3 PUFAs on depression symptoms.

To estimate the effect of each type of omega‐3 PUFA (EPA or DHA), compared with placebo, on depression.

To determine if the effect is modified by dosage, format (capsule or liquid), sex, or age.

To determine compliance and attrition for omega‐3 PUFAs as an intervention for depression in children and adolescents.

To determine the safety of omega‐3 PUFAs as an intervention for depression in children and adolescents.

Search methods
We searched CENTRAL, MEDLINE, Embase, three other databases, reference lists of included studies, grey literature, and relevant reviews. The latest search date was 18 May 2023.

Selection criteria
We included randomized controlled trials (RCTs) involving males and females aged 19 years or younger with diagnosed depression comparing omega‐3 PUFA supplementation to placebo, wait list control, no treatment/supplementation, or standard care.

Data collection and analysis
We used standard Cochrane methods. Our primary outcomes were self‐reported depression symptoms and clinically diagnosed resolution of depression. Our secondary outcomes were attrition, adverse effects, and compliance with the intervention. We used GRADE to assess the certainty of evidence for key outcomes.

Main results
We included five trials with 228 participants in our meta‐analysis. All trials used a placebo comparator; intervention duration ranged from 10 to 16 weeks (median: 12 weeks).

Omega‐3 PUFA supplementation compared to placebo may reduce self‐reported depression symptoms, but the evidence is very uncertain (standardized mean difference [SMD] −0.34, 95% confidence interval [CI] −0.85 to 0.17; lower SMD means greater improvement in depression due to omega‐3 PUFA; 5 trials, 185 participants; very low‐certainty evidence).

Omega‐3 PUFA supplementation may have little to no effect on remission of depression symptoms compared to placebo, but the evidence is very uncertain (omega‐3 PUFA versus placebo: 50% versus 48%; odds ratio [OR] 1.11, 95% CI 0.45 to 2.75; 4 trials, 127 participants; very low‐certainty evidence).

Omega‐3 PUFA supplementation may result in little to no difference in attrition (dropouts) compared to placebo (omega‐3 PUFA versus placebo: 18% versus 19%; OR 0.94, 95% CI 0.46 to 1.90; 5 trials, 228 participants; low‐certainty evidence).

Omega‐3 PUFA supplementation may result in little to no difference in adverse effects, with one study reporting more muscle cramps in the fish oil group (13/27 participants) compared to the placebo group (6/29 participants); one study reported more frequent defecation in the omega‐3 group (1/29 participants) and one study identified mild skin rash and unusual/manic behavior in the placebo group (2/27 participants).

None of the included studies reported serious adverse effects.

Authors' conclusions
Based on five small studies, omega‐3 PUFA supplementation may reduce self‐reported depression symptoms, but the evidence is very uncertain. Omega‐3 PUFA supplementation may have little to no effect on depression remission compared to placebo, but the evidence is very uncertain. Omega‐3 PUFA supplementation may result in little to no difference in attrition or adverse effects. The studies observed no serious adverse effects.

This review highlights early‐stage research on omega‐3 PUFA and depression in young people. The evidence on the effects of omega‐3 PUFA supplementation in improving self‐reported depression symptoms or achieving depression remission in children and adolescents is very uncertain. While no harms are evident, more data are needed to confirm potential risks.

Addressing current limitations in the evidence base through the design and conduct of methodologically rigorous studies — larger sample sizes, varied dosages, eicosapentaenoic acid/docosahexaenoic acid ratios, treatment durations, and safety profiles — is crucial to advance our understanding of the role of omega‐3 PUFA supplementation for depression in children and adolescents.
AN  - CD014803
AU  - Campisi,
AU  - S.
AU  - C.
AU  - Zasowski,
AU  - C.
AU  - Bradley-Ridout,
AU  - G.
AU  - Schumacher,
AU  - A.
AU  - Szatmari,
AU  - P.
AU  - Korczak,
AU  - D.
DB  - November 2024.enl
DO  - 10.1002/14651858.CD014803.pub2
L1  - internal-pdf://1706569574/Campisi_et_al-2024-Cochrane_Database_of_System.pdf
N1  - [Central Editorial Service]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Omega‐3 fatty acid supplementation for depression in children and adolescents
UR  - https://doi.org//10.1002/14651858.CD014803.pub2
ER  -
TY  - JOUR
AB  - BACKGROUND: The manifestation of complex trauma results from exposure to severe and repetitive stressors occurring within the caregiver system. Frequently associated with child maltreatment, complex trauma can lead to impairments in multiple domains, including attachment, affect and behavioural regulation, and cognition. Treatments, including Trauma-Focused Cognitive Behavioural Therapy, have been shown to be efficacious, but high attrition rates point to the need for complementary methods that boost client retention and treatment efficacy. This systematic review examines whether dog-assisted therapy has beneficial impacts on the treatment of complex trauma and whether it can decrease treatment attrition among children presenting with complex trauma exposure. 

METHODS: We followed PRISMA guidelines to locate relevant research reports. Seven published research reports matched the inclusion criteria. 

RESULTS: Dog-assisted therapy may increase the efficacy of standard interventions for complex trauma, although only one study formally assessed treatment retention. Across most studies, there is an overall lack of detailed information on the nature of therapeutic activities involving the dog and how these activities may complement or enhance therapy as usual. Studies were of varying methodological quality, impacting the reliability of findings. 

CONCLUSIONS: Future studies should aim to better describe and justify dog-assisted therapy techniques and evaluate these in comparison with standard evidence-based approaches to the treatment of childhood complex trauma.
AN  - 39201951
AU  - Chapman,
AU  - R.
AU  - L.
AU  - Baselmans,
AU  - C.
AU  - Howell,
AU  - T.
AU  - J.
AU  - Ronken,
AU  - C.
AU  - Butler,
AU  - D.
DB  - September 2024.enl
DO  - /10.3390/children11081017
L1  - internal-pdf://3421458328/Chapman-2024-Exploring the Benefits of Dog-Ass.pdf
PY  - 2024
SP  - 20
T2  - Children
TI  - Exploring the Benefits of Dog-Assisted Therapy for the Treatment of Complex Trauma in Children: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=pmnm&DO=10.3390%2fchildren11081017
UR  - https://mdpi-res.com/d_attachment/children/children-11-01017/article_deploy/children-11-01017.pdf?version=1724160265
VL  - 11
ER  -
TY  - JOUR
AB  - AIM: To determine the treatment effect of resistance training in reducing symptoms of anxiety and depression in young people.

METHODS: We searched MEDLINE, PsychINFO, and PubMed for articles published in English from January 1980 to September 2023 for randomized controlled trials (RCT) that included at least 4 weeks of resistance training, with participants aged 26 years or younger with clinically elevated anxiety and depression symptoms. A random-effects meta-analysis was used to calculate a pooled effect size of resistance training pre-and post-intervention compared to control groups. The quality of evidence was assessed using the Cochrane risk-of-bias 2 (RoB 2) and Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) criteria. 

RESULTS: Ten RCTs involving 376 participants (209 females and 127 males) across educational, clinical, and community based setting were eligible for inclusion in the analysis. Resistance training was associated with a significant reduction in depressive (Hedge's g = -1.06, 95% CI -1.61 to -0.51, p < .001) and anxiety (Hedge's g = -1.02, 95% CI -1.50 to -0.54, p < .001) symptoms. Substantial heterogeneity was observed in the analysis of depression symptoms (I<sup>2</sup> = 79%) and anxiety symptoms (I<sup>2</sup> = 66%). Six trials had a low risk of bias, four trials showed some concerns. The GRADE analysis demonstrated a high level of certainty for depressive symptoms and a moderate level for anxiety symptoms. 

CONCLUSION: Resistance training is an effective intervention in reducing depression and anxiety symptoms in young people, delivered across a range of settings. Future trials exploring the effect resistance training interventions with long-term follow up are warranted to understand the outcomes.
AN  - 38710640
AU  - Marinelli,
AU  - R.
AU  - Parker,
AU  - A.
AU  - G.
AU  - Levinger,
AU  - I.
AU  - Bourke,
AU  - M.
AU  - Patten,
AU  - R.
AU  - Woessner,
AU  - M.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1111/eip.13528
L1  - internal-pdf://3593101359/Early Intervention Psych - 2024 - Marinelli -.pdf
PY  - 2024
SP  - 06
T2  - Early intervention in psychiatry
TI  - Resistance training and combined resistance and aerobic training as a treatment of depression and anxiety symptoms in young people: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1111%2feip.13528
VL  - 06
ER  -
TY  - JOUR
AB  - OBJECTIVE: To systematically evaluate the safety and efficacy of antioxidant therapy in children and adolescents with attention deficit hyperactivity disorder (ADHD). 

METHODS: Randomized controlled trials and prospective studies on antioxidant therapy in children and adolescents with ADHD were searched in PubMed, Embase, and Cochrane Library from the inception of databases to November 12, 2022. Two investigators independently screened the literature, extracted data, and evaluated the quality of the included studies. Network meta-analysis (PROSPERO registration number CRD 42023382824) was carried out by using R Studio 4.2.1. 

RESULTS: 48 studies involving 12 antioxidant drugs (resveratrol, pycnogenol, omega-3, omega-6, quercetin, phosphatidylserine, almond, vitamin D, zinc, folic acid, ginkgo biloba, Acetyl-L-carnitine) were finally included, with 3,650 patients. Network meta-analysis showed that omega-6 (0.18), vitamin D (0.19), and quercetin (0.24) were the top three safest drugs according to SUCRA. The omega-3 (SUCRA 0.35), pycnogenol (SUCRA 0.36), and vitamin D (SUCRA 0.27) were the most effective in improving attention, hyperactivity, and total score of Conners' parent rating scale (CPRS), respectively. In terms of improving attention, hyperactivity, and total score of Conners' teacher rating scale (CTRS), pycnogenol (SUCRA 0.32), phosphatidylserine+omega-3 (SUCRA 0.26), and zinc (SUCRA 0.34) were the most effective, respectively. In terms of improving attention, hyperactivity and total score of ADHD Rating Scale-Parent, the optimal agents were phosphatidylserine (SUCRA 0.39), resveratrol+MPH (SUCRA 0.24), and phosphatidylserine (SUCRA 0.34), respectively. In terms of improving attention, hyperactivity and total score of ADHD Rating Scale-Teacher, pycnogenol (SUCRA 0.32), vitamin D (SUCRA 0.31) and vitamin D (SUCRA 0.18) were the optimal agents, respectively. The response rate of omega-3+6 was the highest in CGI (SUCRA 0.95) and CPT (SUCRA 0.42). 

CONCLUSION: The rankings of safety and efficacy of the 12 antioxidants vary. Due to the low methodological quality of the included studies, the probability ranking cannot fully explain the clinical efficacy, and the results need to be interpreted with caution. More high-quality studies are still needed to verify our findings.
AN  - 38547138
AU  - Zhou,
AU  - P.
AU  - Yu,
AU  - X.
AU  - Song,
AU  - T.
AU  - Hou,
AU  - X.
DB  - Mars 24.enl
DO  - /10.1371/journal.pone.0296926
L1  - internal-pdf://0966968736/Zhou-2024-Safety and efficacy of antioxidant t.pdf
PY  - 2024
SP  - e0296926
T2  - PLoS ONE [Electronic Resource]
TI  - Safety and efficacy of antioxidant therapy in children and adolescents with attention deficit hyperactivity disorder: A systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&DO=10.1371%2fjournal.pone.0296926
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0296926&type=printable
VL  - 19
ER  -
TY  - JOUR
AB  - INTRODUCTION: Mentalization-based therapy (MBT) and its adapted version for adolescents (MBT-A) are repeatedly highlighted as promising treatments for reducing self-harm, particularly in borderline personality disorder (BPD). Despite the availability of publications providing evidence of their efficacy in reducing self-harm, recent meta-analyses have yielded mixed results. To inform best-practice clinical decision-making, we conducted a systematic review and meta-analysis. We aimed to disentangle findings for both adolescents and adults on the efficacy of MBT(-A) in reducing self-harm (primary outcome) and symptoms of BPD and depression (secondary outcomes). 

METHODS: Web of Science, Scopus, Embase, PubMed/Medline, and Cochrane Review Database were searched for eligible studies published until September 2022. In total, 14 studies were identified, comprising 612 participants from nine MBT studies (six pre-post, three RCTs) and five MBT-A studies (two pre-post, three RCTs). Aggregated effect sizes were estimated using random-effects models. Meta-regressions were conducted to assess the effect of moderator variables (treatment duration, drop-out rates, and age) on effect sizes. 

RESULTS: Overall, both MBT and MBT-A demonstrated promising effects in reducing self-harm (g = -0.82, 95% CI -1.15 to -0.50), borderline personality disorder (g = -1.08, 95% CI -1.38 to -0.77), and depression (g = -1.1, 95% CI -1.52 to -0.68) symptoms. However, when compared to control interventions (TAU, SCM), MBT(-A) did not prove to be more efficacious, with the exception of MBT showing superior effects on BPD symptoms in adults (g = -0.56, 95% CI -0.88 to -0.24). 

CONCLUSION: Although the pre-post evaluations seem promising, this analysis, including RCTs, showed no superiority of MBT(-A) to control conditions, so that prioritizing the application of MBT (-A) for the treatment of self-harm is not supported. Possible explanations and further implications are discussed.
AN  - 38279664
AU  - Hajek
AU  - Gross,
AU  - C.
AU  - Oehlke,
AU  - S.
AU  - M.
AU  - Prillinger,
AU  - K.
AU  - Goreis,
AU  - A.
AU  - Plener,
AU  - P.
AU  - L.
AU  - Kothgassner,
AU  - O.
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/sltb.13044
L1  - internal-pdf://1625323960/Hajek Gross-2024-Efficacy of mentalization-bas.pdf
PY  - 2024
SP  - 27
T2  - Suicide & Life Threatening Behavior
TI  - Efficacy of mentalization-based therapy in treating self-harm: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=38279664
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/sltb.13044?download=true
VL  - 27
ER  -
TY  - JOUR
AB  - **Objective**
The purpose of this systematic review and meta-analysis is to provide an updated examination of the adolescent Dialectical Behavioral Therapy (DBT) literature and synthesize study findings across treatment settings (e.g. inpatient, outpatient, school), and treatment levels (e.g. clinical intervention, targeted, universal prevention). We also provide meta-analytic findings of the impact of DBT across key problem behaviors: depression, emotion dysregulation, suicidal and self-harm behaviors, externalizing problems, and eating disorders.

**Method**
A reference database search was used to identify studies conducted on adolescent DBT interventions from 2000 through 2023 (N = 72). In addition to ensuring that the review process conformed to the PRISMA statement, we independently verified that each study met inclusion criteria before triple coding each article to examine variables of interest and extracted outcome data needed to conduct meta-analyses.

**Results**
DBT appears to demonstrate effectiveness in improving mental health outcomes in adolescents across a range of psychiatric problems. To meet these treatment needs, DBT interventions have been appropriately adapted based on care setting, suggesting empirical support in inpatient, residential, partial hospitalization, and intensive outpatient programs, as well as in outpatient settings, juvenile correctional facilities, and schools.

**Conclusions**
The growing evidence base for adolescent DBT appears to reflect its promise and versatile clinical utility. Clinical implications and recommendations for future directions are discussed, including the need for more randomized controls and representation of diverse communities.
AN  - WOS:001359405800001
AU  - Boustani,
AU  - M.
AU  - Mazzone,
AU  - E.
AU  - Hodgins,
AU  - J.
AU  - Rith-Najarian,
AU  - L.
DB  - November 2024.enl
DO  - 10.1080/15374416.2024.2426142
L1  - internal-pdf://1374320750/Dialectical Behavior Therapy Programming for A.pdf
PY  - 2024
SP  - 16
T2  - Journal of Clinical Child and Adolescent Psychology
TI  - Dialectical Behavior Therapy Programming for Adolescents: A Systematic Review and Meta-Analysis of Clinical and Implementation Outcomes
UR  - <Go to ISI>://WOS:001359405800001
ER  -
TY  - JOUR
AB  - **Objective**
Adolescents are particularly susceptible to developing an eating disorder (ED). Therefore, schools are in a unique position to assist in the prevention of EDs for this vulnerable group. To ascertain the current evidence-base for school-based ED prevention efforts, we conducted a systematic review and meta-analysis of randomised controlled trials that delivered a school-based ED prevention intervention and assessed the impact these interventions had on ED symptomatology.

**Method**
Electronic databases (PsycINFO, MEDLINE, EMBASE, Web of Science, Scopus and CENTRAL) were searched for published randomised controlled trials of school-based ED prevention interventions from inception to 2024. Twelve studies from 11 articles were identified with 7935 participants (mean ages ranging from 12 to 17). Of these studies, six were included in meta-analyses.

**Results**
Media literacy and dissonance-based interventions reported small to medium effects for ED symptomatology compared to controls at post-intervention. At three-to-six-month follow-up, intervention groups reported small negative to medium-sized positive effects compared to control groups on eating disorder symptomatology.

**Conclusions**
While school-based ED prevention interventions can effectively reduce ED symptomatology post-intervention, the programs analysed in this review do not reliably demonstrate effectiveness across groups and time. Future research should build upon current interventions to increase effectiveness and include long-term follow-ups.
AN  - WOS:001357038400001
AU  - Berry,
AU  - S.
AU  - L.
AU  - Burton,
AU  - A.
AU  - L.
AU  - Rogers,
AU  - K.
AU  - Lee,
AU  - C.
AU  - M.
AU  - Berle,
AU  - D.
AU  - M.
DB  - November 2024.enl
DO  - 10.1002/erv.3149
L1  - internal-pdf://3357509834/Euro Eating Disorders Rev - 2024 - Berry - A s.pdf
PY  - 2024
SP  - 21
T2  - European Eating Disorders Review
TI  - A systematic review and meta-analysis of eating disorder preventative interventions in schools
UR  - <Go to ISI>://WOS:001357038400001
ER  -
TY  - JOUR
AB  - The level of psychological stress in children and adolescents has increased rapidly over the past decade. The aim of the present meta-analysis was to evaluate the effectiveness of school-based intervention programs targeting stress management and coping/resilience in school-aged children. The present study used more rigorous selection criteria than previous meta-analyses by only including randomized controlled trials to increase the validity of the meta-analysis. Fifty-five studies were selected for the analysis, including 66 comparisons in the case of stress and 47 comparisons in the case of coping/resilience outcomes. A meta-regression with robust variance estimation was used. Effects were calculated as the standardized mean difference (Hedges' g) between the intervention and control conditions at posttest. The results highlighted important methodological issues and the influence of outliers. Without outliers, the results indicated a small significant overall effect on stress (g = -0.15, p < .01) and coping/resilience (g = 0.14, p = .01). When outliers were included, the effect sizes markedly increased in both cases (g(stress) = -0.26, p = .022; g(coping/resilience) = 0.30, p = .009). Stress management interventions were more effective if they were delivered by mental health professionals or researchers than by teachers. Coping/resilience interventions were more effective in older age groups, in selective samples, and if they included cognitive behavioral therapy. An explanation of the results and a detailed discussion of the limitations of the study and its implications for practice are considered.
AN  - WOS:001294124200001
AU  - Juhász,
AU  - A.
AU  - Sebestyén,
AU  - N.
AU  - Arva,
AU  - D.
AU  - Barta,
AU  - V.
AU  - Pártos,
AU  - K.
AU  - Vokó,
AU  - Z.
AU  - Rákosy,
AU  - Z.
DB  - September 2024.enl
DO  - 10.1016/j.jsp.2024.101352
L1  - internal-pdf://0123688667/1-s2.0-S0022440524000724-main.cleaned.pdf
PY  - 2024
SP  - 23
T2  - Journal of School Psychology
TI  - We need better ways to help students avoid the harms of stress: Results of a meta-analysis on the effectiveness of school-based stress management interventions
UR  - <Go to ISI>://WOS:001294124200001
VL  - 106
ER  -
TY  - JOUR
AB  - BACKGROUND>: Sibling sexual abuse (SSA) is the most common form of intra-familial child sexual abuse yet is largely understudied. 

OBJECTIVE: To systematically review the literature on risk and protective factors, disclosure patterns and responses to disclosure, and therapeutic or other responses to cases of sibling sexual abuse. 

METHODS: In line with PRISMA guidelines, six key databases were searched along with a systematic search of key grey literature sources. Studies were then screened with 39 included for review.

RESULTS: SSA behavior was most commonly demonstrated by male siblings with histories of abuse, learning disabilities, and exposure to family conflict, violence, and disadvantage. Rates of disclosure to parents were low, with many victims (most commonly female) not disclosing until adulthood. Parents were also found to often respond poorly by minimising and disbelieving victimized children. 

CONCLUSIONS: Early detection and prevention are paramount to improve outcomes for children and young people, and their families. Professionals working in sectors such as social work, education, health, and mental health need to be aware of the risk and protective factors, disclosure patterns, and appropriate responses to SSA behavior to provide effective support. Our review highlights the need for more awareness-raising and education for parents to address the issue of SSA in families, reduce stigma and barriers to disclosure for victims, and facilitate access to treatment and intervention when harmful sexual behaviors are demonstrated. There is a need for more rigorous research on SSA behavior to support practice development.
AN  - 39551691
AU  - Russell,
AU  - D.
AU  - H.
AU  - Trew,
AU  - S.
AU  - Dickson,
AU  - J.
AU  - Hunt,
AU  - G.
AU  - R.
AU  - Higgins,
AU  - D.
AU  - J.
DB  - November 2024.enl
DO  - /10.1016/j.chiabu.2024.107136
L1  - internal-pdf://0619740309/1-s2.0-S014521342400526X-main.cleaned.pdf
PY  - 2024
SP  - 107136
T2  - Child Abuse & Neglect
TI  - The risk and protective factors, response to disclosure, and interventions for sibling sexual abuse: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1016%2fj.chiabu.2024.107136
UR  - https://www.sciencedirect.com/science/article/pii/S014521342400526X?via%3Dihub
ER  -
TY  - JOUR
AB  - There are over 40 million displaced children and youth worldwide and there is a need promote their mental wellbeing. This study aimed to synthesize evidence regarding promotion interventions to increase wellbeing, resilience, and quality of life (primary outcomes), and prevention interventions to reduce internalizing and externalizing symptoms (secondary outcomes) in this population. The review protocol was registered with PROSPERO (CRD42022329978). Medline, PsycINFO, and Web of Science were searched. Inclusion criteria were: >= 10 participants, sample <= 18 years of age, no parental participation, explicated forced migrant populations, implementation in non-clinical context, and validated measures. Fifteen studies (N interventions = 18, N participants = 5741) were eligible. Two studies included outcomes related to wellbeing and quality of life. The remaining studies reported depression, PTSD, anxiety, internalizing and externalizing behaviours, and behavioural and emotional problems. There was only sufficient data to perform random-effects meta-analysis of depression scores. No significant effects were observed in comparison to control condition in randomized trials (n = 4994, k = 5) but a small significant positive trend was observed in within-group analyses (n = 537, k = 12). Cochrane's risk of bias tools and the GRADE certainty of evidence tool were applied. No studies achieved low risk of bias and certainty of evidence was very low. In sum, there remains a dearth of rigorous intervention studies investigating the effects of promotive and preventative psychological interventions on the wellbeing, resilience, and quality of life of forcibly displaced minors. However, the few eligible studies in this review indicate promise.
AN  - 38627307
AU  - Giles,
AU  - C.
AU  - J.
AU  - Vasthagen,
AU  - M.
AU  - van
AU  - Leuven,
AU  - L.
AU  - Edenius,
AU  - A.
AU  - Ghaderi,
AU  - A.
AU  - Enebrink,
AU  - P.
DB  - April 24.enl
DO  - /10.1007/s00787-024-02424-8
L1  - internal-pdf://1932709607/Giles-2024-The efficacy of psychological preve.pdf
PY  - 2024
SP  - 16
T2  - European Child & Adolescent Psychiatry
TI  - The efficacy of psychological prevention, and health promotion interventions targeting psychological health, wellbeing or resilience among forced migrant children and youth: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&DO=10.1007%2fs00787-024-02424-8
UR  - https://link.springer.com/content/pdf/10.1007/s00787-024-02424-8.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - PURPOSE: Evidence on non-pharmacological interventions for adolescents with type 1 diabetes is unclear. This review aimed to evaluate the effectiveness of non-pharmacological intervention in adolescents with type 1 diabetes. METHODS: We conducted a search on databases from November 11 to 19, 2022, for randomized controlled trials for the effects of non-pharmacological intervention in adolescents with type 1 diabetes. To identify recent research trends, we included studies published from 2017 to November 2022. The risk of bias was assessed using the Cochrane Risk of Bias Tool 2.0. To estimate the effect size, a meta-analysis was performed using RevMan 5.4 program and R Studio. RESULTS: A total of 45 studies were included in the systematic review. Among those, 30 studies were included in the meta-analysis. Non-pharmacological interventions were significantly effective in improving HbA1c (SMD=-0.26, 95% CI: -0.42, -0.09), quality of life (SMD=0.44, 95% CI: 0.13 to 0.76), anxiety (SMD=-0.91, 95% CI: -1.26, -0.56), and blood glucose (SMD=-1.62, 95% CI: -2.22, -1.01). Subgroup analysis showed that duration of intervention was not a covariate related to HbA1c levels. CONCLUSIONS: Non-pharmacological interventions have shown effectiveness in improving the HbA1c, quality of life, anxiety, and blood glucose in adolescents with type 1 diabetes. Future studies with more rigorous methodology are needed to confirm and strengthen the validity of these findings. Additionally, attention to changes in the lipid profile and self-care motivation among adolescents with type 1 diabetes is warranted. Trial registration number: Prospero (crd42022382190).
AN  - 38307162
AU  - DaeEun,
AU  - L.
AU  - Haejung,
AU  - L.
AU  - YoonYoung,
AU  - S.
AU  - Gaeun,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.anr.2024.01.008
L1  - internal-pdf://1104156217/1-s2.0-S1976131724000082-main.cleaned.pdf
PY  - 2024
SP  - 31
T2  - Asian Nursing Research
TI  - Effectiveness of non-pharmacological interventions for adolescents with type 1 diabetes in the last five years: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medp&AN=38307162
UR  - https://www.sciencedirect.com/science/article/pii/S1976131724000082?via%3Dihub
VL  - 31
ER  -
TY  - JOUR
AB  - Background
Because of wars, conflicts, persecutions, human rights violations, and humanitarian crises, about 84 million people are forcibly displaced around the world; the great majority of them live in low‐ and middle‐income countries (LMICs). People living in humanitarian settings are affected by a constellation of stressors that threaten their mental health. Psychosocial interventions for people affected by humanitarian crises may be helpful to promote positive aspects of mental health, such as mental well‐being, psychosocial functioning, coping, and quality of life. Previous reviews have focused on treatment and mixed promotion and prevention interventions. In this review, we focused on promotion of positive aspects of mental health.

Objectives
To assess the effects of psychosocial interventions aimed at promoting mental health versus control conditions (no intervention, intervention as usual, or waiting list) in people living in LMICs affected by humanitarian crises.

Search methods
We searched CENTRAL, MEDLINE, Embase, and seven other databases to January 2023. We also searched the World Health Organization's (WHO) International Clinical Trials Registry Platform and ClinicalTrials.gov to identify unpublished or ongoing studies, and checked the reference lists of relevant studies and reviews.

Selection criteria
Randomised controlled trials (RCTs) comparing psychosocial interventions versus control conditions (no intervention, intervention as usual, or waiting list) to promote positive aspects of mental health in adults and children living in LMICs affected by humanitarian crises. We excluded studies that enrolled participants based on a positive diagnosis of mental disorder (or based on a proxy of scoring above a cut‐off score on a screening measure).

Data collection and analysis
We used standard Cochrane methods. Our primary outcomes were mental well‐being, functioning, quality of life, resilience, coping, hope, and prosocial behaviour. The secondary outcome was acceptability, defined as the number of participants who dropped out of the trial for any reason. We used GRADE to assess the certainty of evidence for the outcomes of mental well‐being, functioning, and prosocial behaviour.

Main results
We included 13 RCTs with 7917 participants. Nine RCTs were conducted on children/adolescents, and four on adults. All included interventions were delivered to groups of participants, mainly by paraprofessionals. Paraprofessional is defined as an individual who is not a mental or behavioural health service professional, but works at the first stage of contact with people who are seeking mental health care. Four RCTs were carried out in Lebanon; two in India; and single RCTs in the Democratic Republic of the Congo, Jordan, Haiti, Bosnia and Herzegovina, the occupied Palestinian Territories (oPT), Nepal, and Tanzania. The mean study duration was 18 weeks (minimum 10, maximum 32 weeks). Trials were generally funded by grants from academic institutions or non‐governmental organisations.

For children and adolescents, there was no clear difference between psychosocial interventions and control conditions in improving mental well‐being and prosocial behaviour at study endpoint (mental well‐being: standardised mean difference (SMD) 0.06, 95% confidence interval (CI) −0.17 to 0.29; 3 RCTs, 3378 participants; very low‐certainty evidence; prosocial behaviour: SMD −0.25, 95% CI −0.60 to 0.10; 5 RCTs, 1633 participants; low‐certainty evidence), or at medium‐term follow‐up (mental well‐being: mean difference (MD) −0.70, 95% CI −2.39 to 0.99; 1 RCT, 258 participants; prosocial behaviour: SMD −0.48, 95% CI −1.80 to 0.83; 2 RCT, 483 participants; both very low‐certainty evidence). Interventions may improve functioning (MD −2.18, 95% CI −3.86 to −0.50; 1 RCT, 183 participants), with sustained effects at follow‐up (MD −3.33, 95% CI −5.03 to −1.63; 1 RCT, 183 participants), but evidence is very uncertain as the data came from one RCT (both very low‐certainty evidence).

Psychosocial interventions may improve mental well‐being slightly in adults at study endpoint (SMD −0.29, 95% CI −0.44 to −0.14; 3 RCTs, 674 participants; low‐certainty evidence), but they may have little to no effect at follow‐up, as the evidence is uncertain and future RCTs might either confirm or disprove this finding. No RCTs measured the outcomes of functioning and prosocial behaviour in adults.

Authors' conclusions
To date, there is scant and inconclusive randomised evidence on the potential benefits of psychological and social interventions to promote mental health in people living in LMICs affected by humanitarian crises. Confidence in the findings is hampered by the scarcity of studies included in the review, the small number of participants analysed, the risk of bias in the studies, and the substantial level of heterogeneity. Evidence on the efficacy of interventions on positive mental health outcomes is too scant to determine firm practice and policy implications. This review has identified a large gap between what is known and what still needs to be addressed in the research area of mental health promotion in humanitarian settings.
AN  - CD014300
AU  - Papola,
AU  - D.
AU  - Prina,
AU  - E.
AU  - Ceccarelli,
AU  - C.
AU  - Cadorin,
AU  - C.
AU  - Gastaldon,
AU  - C.
AU  - Ferreira,
AU  - M.
AU  - C.
AU  - Tol,
AU  - W.
AU  - A.
AU  - van
AU  - Ommeren,
AU  - M.
AU  - Barbui,
AU  - C.
AU  - Purgato,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/14651858.CD014300.pub2
KW  - *Developing Countries
KW  - *Mental Health
KW  - *Quality of Life
KW  - *Randomized Controlled Trials as Topic
KW  - Adaptation, Psychological
KW  - Adolescent
KW  - Adult
KW  - Altruism
KW  - Bias
KW  - Child
KW  - Female
KW  - Health Promotion [methods]
KW  - Humans
KW  - Mental Disorders [therapy]
KW  - Psychosocial Functioning
KW  - Psychosocial Intervention [methods]
KW  - Refugees [psychology]
KW  - Stress Disorders, Post-Traumatic [psychology, therapy]
L1  - internal-pdf://4234305989/Papola_et_al-2024-Cochrane_Database_of_Systema.pdf
N1  - [Common Mental Disorders]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological and social interventions for the promotion of mental health in people living in low‐ and middle‐income countries affected by humanitarian crises
UR  - http://dx.doi.org/10.1002/14651858.CD014300.pub2
ER  -
TY  - JOUR
AB  - OBJECTIVE: This pooled analysis aims to demonstrate the clinical efficacy and safety of combined desmopressin and anticholinergic therapy in the treatment of pediatric nocturnal enuresis (NE).

METHODS: A systematic search was conducted through PubMed, MEDLINE, EMBASE, ResearchGate, and Cochrane Library to identify all randomized controlled trials (RCTs) comparing monotherapy with desmopressin versus combined therapy with desmopressin and anticholinergic agents for the treatment of NE. Data analysis was performed using RevMan version 5.4.1.

RESULTS: This study included 8 RCTs involving a total of 659 patients. The frequencies of complete response (CR), partial response (PR), and nonresponse (NR) were computed for both short-term treatment (1 month) and long-term treatment (3 months). Additionally, alterations in the mean number of NE episodes, adverse events, and relapse were assessed. Our analysis indicates that, in comparison to the monotherapy group, the combination therapy group plays a pivotal role in augmenting the CR odds and diminishing the NR ratios in both short-term and long-term treatments (1 month CR ratio [risk ratio (RR): 1.84; 95% confidence interval (CI): 1.22-2.76; p = 0.003, I<sup>2</sup> = 72%]; 3 months CR ratio [RR: 1.48; 95% CI: 1.25-1.76; p < 0.00001, I<sup>2</sup> = 0%]; 1 month NR ratio [RR: 0.67; 95% CI: 0.55-0.82; p = 0.0001, I<sup>2</sup> = 0%]; 3 months CR ratio [RR: 0.37; 95% CI: 0.19-0.73; p = 0.004, I<sup>2</sup> = 0%]). Furthermore, in both short-term and long-term treatment, the combined therapy group exhibits a greater magnitude of change in the average number of NE episodes compared to patients receiving monotherapy (1 month, mean difference [MD] = -2.97; 95% CI: -4.23 to -1.71, p < 0.0001; 3 months, MD = -4.30; 95% CI: -7.18 to -1.43, p = 0.003). Moreover, the combination therapy group exhibits a significant reduction in the recurrence rate (RR: 0.36; 95% CI: 0.15-0.86; p = 0.02). There is no significant difference in the incidence of adverse events between the two groups (RR: 1.16; 95% CI: 0.58-2.31; p = 0.67). 

CONCLUSION: Combining desmopressin with anticholinergic medications is more effective for NE than desmopressin alone, with lower recurrence and minimal adverse effects.
AN  - 37787540
AU  - Tang,
AU  - G.
AU  - Liu,
AU  - H.
AU  - Wu,
AU  - G.
AU  - Ding,
AU  - G.
AU  - Chu,
AU  - Y.
AU  - Cui,
AU  - Y.
AU  - Wu,
AU  - J.
DB  - Mars 24.enl
DO  - /10.1002/nau.25295
L1  - internal-pdf://1797178597/Tang-2024-The pooled analysis evaluates the th.pdf
PY  - 2024
SP  - 183-195
T2  - Neurourology & Urodynamics
TI  - The pooled analysis evaluates the therapeutic efficacy of desmopressin combined with anticholinergic drugs in the treatment of pediatric nocturnal enuresis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1002%2fnau.25295
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/nau.25295?download=true
VL  - 43
ER  -
TY  - JOUR
AB  - Reviews and meta-analyses were conducted on universal prevention on school bullying, but no systematic scientific attention has been paid to the indicated interventions targeting those students already involved in the bullying phenomenon as victims or as bullies. This review examined 43 studies providing a qualitative and systematic synthesis of what is realized in the school context as indicated actions, deepening the main characteristics of their implementation and their effectiveness. The analysis was conducted separately for interventions targeting those involved in perpetrating behaviors, those who are victimized, and for interventions including both sides. The results showed that most indicated actions are designed for victims and bullies/victims, and for adolescents. In terms of the interventions implemented, the review presented Evidence-Based Interventions specifically ideated for bullying or programs adapted from general mental health, traditional strategies reported in the literature to address bullying/victimization cases, and specific procedures defined as bullying-indicated interventions. Most interventions are delivered by school staff in the case of bullies/victims and bullies target, while for indicated victim interventions, they are generally led by the school psychologist or counsellor. Interventions for bullies included psycho-educational and emotional-focused actions, victims' interventions mainly focused on counselling, clinical, and skills building. Protocols for both targets included relational and mediational approaches. 67% of the studies evaluated the effectiveness, and only in a minority of cases did the intervention result not significant in reducing the different types of outcomes. Research needs to integrate a valid evaluation of effectiveness to discuss the sustainability of these new and traditional interventions. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2025-50217-001
AU  - Annalaura,
AU  - Nocentini
AU  - Benedetta,
AU  - Taddei
AU  - Lisa,
AU  - De
AU  - Luca
AU  - Ersilia,
AU  - Menesini
DB  - Desember 2024.enl
DO  - /10.1007/s40894-024-00255-x
L1  - internal-pdf://0835256490/d953a172-4dd5-4e55-919d-5db7d00c0f8c.pdf
PY  - 2024
SP  - No Pagination Specified
T2  - Adolescent Research Review
TI  - Indicated interventions for youth involved in bullying and victimization behaviors: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=psyc23&DO=10.1007%2fs40894-024-00255-x
UR  - https://link.springer.com/article/10.1007/s40894-024-00255-x
ER  -
TY  - JOUR
AB  - The prevalence of gaming disorder is assumed to be between 2%-5%. The treatment effect of different therapeutic interventions of gaming disorder has not been studied extensively. This systematic review and metaanalysis sought to identify all intervention studies on gaming disorder with a control group, determine the effect of the interventions, and examine moderators. Studies applying a therapeutic intervention and using an appropriate comparison group were identified by searching electronic databases, previous reviews, and reference lists. Data on type of treatment, name of outcome measurement, symptom level and other study characteristics were extracted and analyzed using meta-analysis and meta-regression. A total of 38 studies and 76 effect sizes, originating from 9524 participants were included. RoB2 and ROBINS-I risk of bias tools were used to assess within-study risk of bias. Correlational hierarchical models with robust variance estimation were fitted to effect size data and yielded a moderate summary estimate. Egger's sandwich test, funnel plot inspections, and other tests were conducted to assess risk of bias between studies. Results indicate that there may be an overall effect of therapeutic interventions for gaming disorder, but confidence in these findings is compromised by small-study effects, possible publication bias, a limited study pool, and a lack of standardization. The field needs more higher quality studies before the evidence-base can support reliable meta-analytic estimates.
AN  - WOS:001092150700001
AU  - Danielsen,
AU  - P.
AU  - A.
AU  - Mentzoni,
AU  - R.
AU  - A.
AU  - Låg,
AU  - T.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1016/j.addbeh.2023.107887
L1  - internal-pdf://0761336655/Danielsen_2024.pdf
PY  - 2024
SP  - 17
T2  - Addictive Behaviors
TI  - Treatment effects of therapeutic interventions for gaming disorder: A systematic review and meta-analysis
UR  - <Go to ISI>://WOS:001092150700001
UR  - https://www.sciencedirect.com/science/article/pii/S0306460323002824?via%3Dihub
VL  - 149
ER  -
TY  - JOUR
AB  - **Objective**: To explore the effects of mind-body exercise (MBE) on ADHD through a systematic review and meta-analysis. **Methods**: After identifying relevant search keywords based on the study's technical terminology, research articles were retrieved from five databases. Two researchers independently screened the results to select studies that met the inclusion criteria. A random-effects model was used to conduct a meta-analysis on the included studies. **Results**: The findings indicate that MBE interventions significantly improved attention in individuals with ADHD [SMD=-0.97, 95% CI (-1.56, -0.39), P < 0.05]. However, the meta-analysis found no evidence that MBE improved executive function, emotional issues, or hyperactivity/impulsivity in ADHD patients. **Conclusions**: MBE is beneficial for attention improvement in ADHD patients. However, further evidence is needed to support its efficacy as an adjunctive treatment for other symptoms.
AN  - WOS:001382821500001
AU  - Peng,
AU  - J.
AU  - Wang,
AU  - W.
AU  - R.
AU  - Wang,
AU  - Y.
AU  - T.
AU  - Hu,
AU  - F.
AU  - T.
AU  - Jia,
AU  - M.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.3389/fpsyt.2024.1490708
L1  - internal-pdf://0223295892/Peng-2024-Effects of mind-body exercise on ind.pdf
PY  - 2024
SP  - 10
T2  - Frontiers in Psychiatry
TI  - Effects of mind-body exercise on individuals with ADHD: a systematic review and meta-analysis
UR  - <Go to ISI>://WOS:001382821500001
UR  - https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1490708/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - BACKGROUND: Group trauma-focused cognitive behavior therapy (TF-CBT) is widely used to treat post-traumatic stress disorder (PTSD) in children and adolescents. However, the available evidence remains unclear. 

METHOD: PubMed, EMBASE, Cochrane, Web of Science, PsycINFO, CINAHL, ProQuest Dissertations, LILACS, and international trial registers were searched from database inception to April 30, 2022. We included randomized controlled trials (RCTs) that compared TF-CBT with any control condition for treating children and adolescents with PTSD. Analyses were performed using Review Manager version 5.3 and Stata 16.0. The risk of bias was assessed using the Cochrane Risk of Bias 2.0 tool. This study was registered with PROSPERO (CRD42020206096). 

RESULTS: Eleven RCTs involving 1942 patients were included. Group TF-CBT was significantly more effective than other treatments at post-treatment (standardized mean difference [SMD]: -0.43, 95% confidence interval [CI]: -0.65 to -0.22), follow-up (SMD: -0.33, 95% CI: -0.52 to -0.13), and in relieving depressive symptoms (SMD: -0.29, 95% CI: -0.49 to -0.09), but not in terms of acceptability. Subgroup analyses showed that group TF-CBT was superior to other treatments in studies including children with post-traumatic stress symptoms (PTSS) (SMD: -0.54, 95% CI: -0.79 to -0.28) and psychiatric comorbidities (SMD: -0.48, 95% CI: -0.72 to -0.23). 

LIMITATIONS: The small sample sizes of identified studies limited some findings. 

CONCLUSION: When considering effectiveness at post-treatment and follow-up or the reduction of depressive symptoms, group TF-CBT could be a good choice for children and adolescents with PTSD. Among these patients, those with PTSS or psychiatric comorbidities may benefit the most.
AN  - 38219423
AU  - Xie,
AU  - S.
AU  - Cheng,
AU  - Q.
AU  - Tan,
AU  - S.
AU  - Li,
AU  - H.
AU  - Huang,
AU  - T.
AU  - Xiang,
AU  - Y.
AU  - Zhou,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.genhosppsych.2023.11.012
L1  - internal-pdf://2303300317/1-s2.0-S0163834323001883-main.cleaned (1).pdf
PY  - 2024
SP  - 127-134
T2  - General Hospital Psychiatry
TI  - The efficacy and acceptability of group trauma-focused cognitive behavior therapy for the treatment of post-traumatic stress disorder in children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=mesx&AN=38219423
UR  - https://www.sciencedirect.com/science/article/pii/S0163834323001883?via%3Dihub
VL  - 86
ER  -
TY  - JOUR
AB  - Research is increasingly highlighting the role of negative trauma-related appraisals in child and adolescent post-traumatic stress disorder (PTSD). The cognitive model of PTSD claims that an essential mechanism of treatment is a reduction in these appraisals. The current systematic review with meta-analysis investigated the extent to which psychological treatments for PTSD reduce negative trauma-related appraisals in children and adolescents. Four databases (PsycINFO, Medline Complete, CINAHL Complete and PTSDpubs) were searched on the 11-12th December 2022. The Risk of Bias 2 (ROB-2) tool was used to assess for risk of bias. Thirteen studies were included in this review, comprising 937 child and adolescent participants. Using a random effects model to perform the meta-analysis, a medium pooled effect size for the effect of current treatments on trauma-related appraisals was found (g = -.67, 95% CI [-.86, -.48]). There was only a moderate level of heterogeneity between studies (I<sup>2</sup> = 44.4%), increasing the confidence with which these findings can be interpreted. These results indicate that psychological treatments for child and adolescent PTSD significantly reduce negative trauma-related appraisals. However, it is important to note that no trial included in the review was categorised as having low risk of bias.
AN  - 39213739
AU  - Smith,
AU  - C.
AU  - Ford,
AU  - C.
AU  - Baldwin,
AU  - G.
AU  - Jensen,
AU  - T.
AU  - K.
AU  - Karatzias,
AU  - T.
AU  - Birkeland,
AU  - M.
AU  - S.
AU  - Meiser-Stedman,
AU  - R.
DB  - September 2024.enl
DO  - /10.1016/j.brat.2024.104621
L1  - internal-pdf://3390395405/1-s2.0-S0005796724001487-main.pdf
PY  - 2024
SP  - 104621
T2  - Behaviour Research & Therapy
TI  - Do psychological treatments for PTSD in children and young people reduce trauma-related appraisals? A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&D=medl&DO=10.1016%2fj.brat.2024.104621
VL  - 182
ER  -
TY  - JOUR
AB  - Objective: To explore the efficacy of sandplay therapy in intervening social communication deficits in children with autism spectrum disorders (ASD), and whether this efficacy is influenced by the age of the children and the dosage of sandplay therapy intervention. 

Methods: Following the PICOS principle, randomized controlled trials (RCTs) related to sandplay therapy for social communication deficits in ASD children were retrieved from seven databases: PubMed, WOS, The Cochrane Library, Embase, CNKI, Wanfang, and VIP, from the inception of each database to November 10, 2023. Two experimenters independently conducted study screening and excluded studies with concomitant diseases, incomplete data, unextractable data, and non-randomized controlled trials. The PEDro scale was used for methodological quality assessment, and the GRADEprofiler method was employed to evaluate the quality of evidence. Stata17 software was used for meta-analysis, subgroup analysis, sensitivity analysis, and publication bias testing. The standardized mean difference (SMD) and 95% confidence interval (CI) were used as the effect statistics. 

Results: A total of 12 RCTs (791 cases) were included. Sandplay therapy had a positive impact on the social communication deficits of ASD children [SMD = -1.42, 95%CI (-1.79, -1.04), P < 0.001]. Subgroup analysis revealed that sandplay therapy administered during the early school age (449 cases, SMD = -1.44, P < 0.05), for a duration of 22-28 weeks (208 cases, SMD = 1.69, P < 0.05), and with a frequency of once per week (218 cases, SMD = -1.67, P < 0.05) was most effective in improving on social communication deficits of ASD children. 

Discussion: The quality of evidence in this study was rated as high, with good methodological quality, including 12 studies with better quality and no detection of bias risk. The study had high heterogeneity, which was attributed to the measurement tools and intervention duration through subgroup analysis, with no inconsistency found. Additionally, no downgrade factors related to imprecision, publication bias, or indirectness were identified. In conclusion, sandplay therapy is an effective measure to improve social communication deficits in children with ASD, and current evidence recommends early intervention using an individual sandplay therapy or integrated sandplay therapy intervention program once a week for 22-28 weeks, which can serve as evidence-based clinical guidance. 

<b>Systematic Review Registration</b>: www.crd.york.ac.uk, identifier (CRD420234821750).
AN  - 39463730
AU  - Yuxi,
AU  - R.
AU  - Shuqi,
AU  - J.
AU  - Cong,
AU  - L.
AU  - Shufan,
AU  - L.
AU  - Yueyu,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fped.2024.1454710
L1  - internal-pdf://0153094747/Yuxi-2024-A systematic review of the effect of.pdf
PY  - 2024
SP  - 1454710
T2  - Frontiers in Pediatrics
TI  - A systematic review of the effect of sandplay therapy on social communication deficits in children with autism spectrum disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffped.2024.1454710
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11502332/pdf/fped-12-1454710.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **Importance** 
Problem-solving skills training (PSST) has a demonstrated potential to improve psychosocial well-being for parents of children with chronic health conditions (CHCs), but such evidence has not been fully systematically synthesized.

**Objective** 
To evaluate the associations of PSST with parental, pediatric, and family psychosocial outcomes.

**Data Sources** 
Six English-language databases (PubMed, Embase, CINAHL, PsycINFO, Web of Science, and Cochrane Library), 3 Chinese-language databases (China National Knowledge Infrastructure, China Science and Technology Journal Database, and Wanfang), gray literature, and references were searched from inception to April 30, 2023.

**Study Selection** 
Randomized clinical trials (RCTs) that performed PSST for parents of children with CHCs and reported at least 1 parental, pediatric, or family psychosocial outcome were included.

**Data Extraction and Synthesis** 
Study selection, data extraction, and quality assessment were conducted independently by 2 reviewers. Data were pooled for meta-analysis using the standardized mean difference (SMD) by the inverse variance method or a random-effects model. Subgroup analyses of children- and intervention-level characteristics were conducted.

**Main Outcomes and Measures** 
The psychosocial outcomes of the parents, their children, and their families, such as problem-solving skills, negative affectivity, quality of life (QOL), and family adaptation.

**Results** 
The systematic review included 23 RCTs involving 3141 parents, and 21 of these trials were eligible for meta-analysis. There was a significant association between PSST and improvements in parental outcomes, including problem-solving skills (SMD, 0.43; 95% CI, 0.27-0.58), depression (SMD, -0.45; 95% CI, -0.66 to -0.23), distress (SMD, -0.61; 95% CI, -0.81 to -0.40), posttraumatic stress (SMD -0.39; 95% CI, -0.48 to -0.31), parenting stress (SMD, -0.62; 95% CI, -1.05 to -0.19), and QOL (SMD, 0.45; 95% CI, 0.15-0.74). For children, PSST was associated with better QOL (SMD, 0.76; 95% CI, 0.04-1.47) and fewer mental problems (SMD, -0.51; 95% CI, -0.68 to -0.34), as well as with less parent-child conflict (SMD, -0.38; 95% CI, -0.60 to -0.16). Subgroup analysis showed that PSST was more efficient for parents of children aged 10 years or younger or who were newly diagnosed with a CHC. Significant improvements in most outcomes were associated with PSST delivered online.

**Conclusions and Relevance** 
These findings suggest that PSST for parents of children with CHCs may improve the psychosocial well-being of the parents, their children, and their families. Further high-quality RCTs with longer follow-up times and that explore physical and clinical outcomes are encouraged to generate adequate evidence.
AN  - WOS:001136984300002
AU  - Zhou,
AU  - T.
AU  - J.
AU  - Luo,
AU  - Y.
AU  - H.
AU  - Xiong,
AU  - W.
AU  - J.
AU  - Meng,
AU  - Z.
AU  - Y.
AU  - Zhang,
AU  - H.
AU  - Y.
AU  - Zhang,
AU  - J.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1001/jamapediatrics.2023.5753
L1  - internal-pdf://4016084505/Zhou-2024-Problem-Solving Skills Training for.pdf
PY  - 2024
SP  - 11
T2  - Jama Pediatrics
TI  - Problem-Solving Skills Training for Parents of Children With Chronic Health Conditions
UR  - &lt;Go to ISI&gt;://WOS:001136984300002
UR  - https://watermark.silverchair.com/jamapediatrics_zhou_2024_oi_230089_1702572633.21551.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAy8wggMrBgkqhkiG9w0BBwagggMcMIIDGAIBADCCAxEGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMpcQeyGGYlyIoGQw6AgEQgIIC4vE1CRtY1zUQByztij2UmkGrcC6fQ3oCDsWu4fRtckLDnQjw4jMXuZaU866jJf6JCFZ5pVvBDtUtaeLUovxWG5XS9t4iDwXOx6_rOsv-Uw1e4ZCKKk0uw4hIQmZsHObCjNtnPF056pSb_eWsc-FJ73V75s320WltlI390Uq0XM9Gq6BMS34ihOvk5Do6_xq061DkHr2y7Y2LR6NpLwnSrnXUciJxXZUusLkXW1fRhZuadvH_rZmO6GjCYHjPo_5fLVQh5IQqj8RemKHQQwW6MKHxeJrASEFQRatlJDLBp64RiHLNVewdyOGwzU0qAzi7NleKZ26Ud7oVxdHFcyKxeBbxi6-UCs6LLabXSwrNT0N8jFIqprgF_ALD7dqH1219j608Tcr8VzyJaVmSXX_A7mZJ10OGrYJPrnm0UQfC9v0cTdn2rdWF6ooOj219xqzEjd4otuhIDw38C-SF3qS2Zf4sKqotSD59ZserrAyT3tVXES6ax_PEoA26K4mcuIIbOJXMpJXyAFXig5pdO7Cooix6HhLLnfqAEJACzd5bXGGStdo6nl2T2olQ2uridw8z9yRrd-grWBG_FkATNcVMEBuGVsxFeItabo0eCEgNGkjD94pXIR1BHR_14JkmsFiZRcRFgtzy2Cu6fydEyZzZRtzsdSKz7kia2U4h9aLq1YZUANqXIGPRH5L3uXJTkTqdJMWSc2MEvKScrn3AI9UEiEwHgxpqAw_3lqaeoZ6y-3upC0PThz-LzgNwiALbyefC_Q1z1Rknngo1UK2nteYKqlazO2jsPOM9ThbDGBdAwOmTZWvrSugdOvEsyKVEf_oczpvzpAG4Vc7f06TSw6U3MeIcAqpbyhpDF0uLieFc-iVCYobQACSKtLkKeXUe5Eh0zVTfubnG4rZivb_w9HaG6If4A7vB8QQnO624xmtNf9c9J4uIXFOa7Kn9qJdXZFcqIFdTkxP5dqgDlDiQsZnKX59pkw
ER  -
TY  - JOUR
AB  - OBJECTIVE: This umbrella review of systematic reviews and meta-analyses evaluates the effectiveness of Solution-Focused Brief Therapy (SFBT) across various populations and settings. 

METHOD: A total of 25 systematic reviews, including 15 meta-analyses, were analyzed. Reviews were included if they used systematic search methods and quality assessments and focused on the effectiveness of SFBT as a therapeutic approach. 

RESULTS: SFBT demonstrated significant positive outcomes across different issues, settings, and cultural contexts, with no evidence of harm. High confidence in evidence of effectiveness was established for depression, overall mental health, and progress towards individual goals for the adult population. In addition, findings indicated mainly moderate confidence in evidence of SFBT effectiveness for a wide variety of outcomes for all age groups. No difference was found in the confidence in the evidence by world region, though Western and Eastern studies researched some different aspects.

CONCLUSION: SFBT is an effective therapeutic approach for various psychological, social, school, medical, couple, or self-related issues. Further research with rigorous methodologies and comprehensive reporting is needed to strengthen the confidence in these findings and provide evidence for the brevity of the intervention.
AN  - 39324877
AU  - Zak,
AU  - A.
AU  - M.
AU  - Pekala,
AU  - K.
DB  - September 2024.enl
DO  - /10.1080/10503307.2024.2406540
L1  - internal-pdf://0335500941/Effectiveness of solution-focused brief therap.pdf
PY  - 2024
SP  - 1-13
T2  - Psychotherapy Research
TI  - Effectiveness of solution-focused brief therapy: An umbrella review of systematic reviews and meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1080%2f10503307.2024.2406540
ER  -
TY  - JOUR
AB  - This study systematically identified the effects of physical activity (PA) on depression, anxiety and weight-related outcomes among children and adolescents with overweight/obesity. EMBASE, The Cochrane Library, Web of Science, and PubMed were searched from January 1, 2000 to August 1, 2022 for peer-reviewed papers. Meta-analyses were conducted to ascertain the effect of physical activity on symptoms of anxiety, depression and weight-related outcomes in overweight/obese children and adolescents. Twenty-five studies representing 2188 participants, with median age 12.08 years old (8.3 to 18.44 years) were included. Depressive and anxiety symptoms, BMI, BMI z-scores, weight, waist circumference and height were evaluated. After incorporating the effects of PA interventions on children and adolescents with overweight/obesity, PA could improve depressive and anxiety symptoms, but not obesity indexes except waist circumference. While, PA combined with other interventions have a significant effect both on anxiety symptoms and BMI compared to pure PA intervention. In terms of intervention duration, we observed that durations falling within the range of 8 to 24 weeks exhibited the most positive effects on reducing depressive symptoms. <b>FOR SHORT COMMUNICATIONS</b>: We included 25 articles on the effects of physical activity on psychological states such as depression and anxiety, weight, BMI and other weight-related indicators in children and adolescents with overweight/obesity. We attempted to determine the most appropriate type of physical activity intervention for children and adolescents with overweight/obesity, as well as the most appropriate population characteristics and duration by combining the outcome data from each article. This has a great enlightening effect for health workers to carry out corresponding strategies in the future.
AN  - 38490590
AU  - Chen,
AU  - L.
AU  - Liu,
AU  - Q.
AU  - Xu,
AU  - F.
AU  - Wang,
AU  - F.
AU  - Luo,
AU  - S.
AU  - An,
AU  - X.
AU  - Chen,
AU  - J.
AU  - Tang,
AU  - N.
AU  - Jiang,
AU  - X.
AU  - Liang,
AU  - X.
DB  - Mars 24.enl
DO  - /10.1016/j.jad.2024.02.092
L1  - internal-pdf://0401131100/1-s2.0-S0165032724004087-main.cleaned.pdf
PY  - 2024
SP  - 275-285
T2  - Journal of Affective Disorders
TI  - Effect of physical activity on anxiety, depression and obesity index in children and adolescents with obesity: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jad.2024.02.092
UR  - https://www.sciencedirect.com/science/article/pii/S0165032724004087?via%3Dihub
VL  - 354
ER  -
TY  - JOUR
AB  - A significant proportion of youth with depression do not respond to available treatment. Transcranial direct current stimulation (tDCS) is a promising third-line treatment in depressed adults, but evidence in youth seems scarce. Following the PRISMA guidelines, we conducted a systematic literature review on tDCS treatment for depression in children and adolescents. No published studies were found on the use of tDCS in youth with depression. Given the null-findings, no conclusion can be drawn about the effectiveness of tDCS treatment for adolescent depression. The reasons for this paucity of evidence in light of existing regulatory frameworks and technical challenges are discussed.
AN  - WOS:001125949300001
AU  - V&ouml;ckel,
AU  - J.
AU  - Spitznagel,
AU  - N.
AU  - Markser,
AU  - A.
AU  - Sigrist,
AU  - C.
AU  - Koenig,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.ajp.2023.103838
L1  - internal-pdf://3570110838/1-s2.0-S1876201823003957-main.cleaned.pdf
PY  - 2024
SP  - 4
T2  - Asian Journal of Psychiatry
TI  - A paucity of evidence in youth: The curious case of transcranial direct current stimulation for depression
UR  - &lt;Go to ISI&gt;://WOS:001125949300001
UR  - https://www.sciencedirect.com/science/article/pii/S1876201823003957?via%3Dihub
VL  - 91
ER  -
TY  - JOUR
AB  - This study aimed to examine the efficacy of school-based e-cigarette preventive interventions via a systematic review and meta-analysis. We searched Medline, Embase, PsycINFO, Scopus, CINAHL, Cochrane, and clinical trial registries for studies published between January 2000 and June 2023 using keywords for e-cigarettes, adolescents, and school. Of 1566 double-screened records, 11 met the criteria of targeting adolescents, evaluating an e-cigarette preventive intervention, being conducted in a secondary school, using a randomized controlled trial (RCT), cluster RCT, or quasi-experimental design, and comparing an intervention to a control. Pre-specified data pertaining to the study design, outcomes, and quality were extracted by one reviewer and confirmed by a second, and where necessary, a third reviewer. Meta-analyses found no evidence that school-based interventions prevented e-cigarette use at the longest follow-up, which ranged between 6 and 36 months post-intervention (OR = 0.43, 95% CI = 0.16, 1.12; p = 0.09). However, subgroup analyses identified significant effects at post-test and when studies with &lt; 12-month follow-up were omitted. No effect was found for tobacco use at the longest follow-up (OR = 1.01, 95% CI = 0.65, 1.59, p = 0.95); however, reductions in past 30-day tobacco use (OR = 0.59, 95% CI = 0.39, 0.89, p = 0.01) which encompassed e-cigarettes in some studies were identified. Narrative synthesis supported these mixed results and found some school-based interventions prevented or reduced e-cigarette and/or tobacco use; however, some increased use. School-based interventions were also associated with improved knowledge (SMD = - 0.38, 95% CI = - 0.68, - 0.08, p = 0.01), intentions (SMD = - 0.15, 95% CI = - 0.22, - 0.07, p = 0.0001), and attitudes (SMD = - 0.14, 95% CI = - 0.22, - 0.06; p = 0.0007) in the short term. Overall, the quality of evidence was low-to-moderate. School-based interventions hold the potential for addressing e-cigarette use, however, can have null or iatrogenic effects. More high-quality research is needed to develop efficacious interventions, and schools must be supported to adopt evidence-based programs. This is the first systematic review and meta-analysis to examine the efficacy of school-based preventive interventions for e-cigarette use. It provides crucial new knowledge about the efficacy of such interventions in preventing e-cigarette use and improving other outcomes (e.g., tobacco use, knowledge, intentions, attitudes, and mental health) among adolescents and the key characteristics associated with efficacious interventions. Our findings have important practical implications, highlighting future research directions for the development and evaluation of e-cigarette preventive interventions, along with the need to provide support to schools to help them identify and adopt evidence-based programs.
AN  - 39325296
AU  - Gardner,
AU  - L.
AU  - A.
AU  - Rowe,
AU  - A.
AU  - L.
AU  - Newton,
AU  - N.
AU  - C.
AU  - Egan,
AU  - L.
AU  - Hunter,
AU  - E.
AU  - Devine,
AU  - E.
AU  - K.
AU  - Aitken,
AU  - T.
AU  - Thornton,
AU  - L.
AU  - Teesson,
AU  - M.
AU  - Stockings,
AU  - E.
AU  - Champion,
AU  - K.
AU  - E.
DB  - September 2024.enl
DO  - /10.1007/s11121-024-01730-6
L1  - internal-pdf://2979878729/Gardner-2024-A Systematic Review and Meta-anal.pdf
PY  - 2024
SP  - 26
T2  - Prevention Science
TI  - A Systematic Review and Meta-analysis of School-Based Preventive Interventions Targeting E-Cigarette Use Among Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs11121-024-01730-6
UR  - https://link.springer.com/content/pdf/10.1007/s11121-024-01730-6.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder characterized by symptoms of inattention, hyperactivity, and impulsivity. Individuals with ADHD often encounter heightened emotional and behavioral challenges. This study aims to conduct a meta-analysis of the efficacy of digital interventions in improving symptoms of ADHD. 

METHODS: This study searched 6 databases for English articles from database construction until December 4, 2023. Randomized controlled trials employing digital interventions for ADHD were gathered. Following the Cochrane Collaboration criteria, Review Manager 5.3 software was utilized to evaluate the risk of bias present in the included papers. Mean differences for post-intervention and follow-up data were standardized using Stata 18.0 software. Subgroup analysis was employed to investigate the sources of heterogeneity. The study adhered to the PRISMA guidelines and was registered on the PROSPERO platform (CRD42024504134). 

RESULTS: This review included a total of 25 randomized controlled trials (RCTs). The combined study population comprised 1780 cases. In the digital intervention groups, there was a significant decrease in overall ADHD symptoms (SMD = -0.33; 95 % CI = [-0.51, -0.16]) compared to the control groups. Furthermore, there was a significant reduction in inattention symptoms (SMD = -0.31; 95 % CI = [-0.46, -0.15]) and hyperactivity/impulsivity symptoms (SMD = -0.15; 95 % CI = [-0.29, -0.02]) within the digital intervention groups. 

CONCLUSION: The digital interventions proved beneficial for individuals with ADHD by alleviating symptoms of ADHD, inattention, and hyperactivity/impulsivity.
AN  - 39191306
AU  - Liu,
AU  - X.
AU  - Yang,
AU  - Y.
AU  - Ye,
AU  - Z.
AU  - Wang,
AU  - F.
AU  - Zeng,
AU  - K.
AU  - Sun,
AU  - Y.
AU  - Huang,
AU  - Y.
AU  - Dai,
AU  - L.
DB  - September 2024.enl
DO  - /10.1016/j.jad.2024.08.156
L1  - internal-pdf://2006078320/1-s2.0-S0165032724013910-main.cleaned.pdf
PY  - 2024
SP  - 563-577
T2  - Journal of Affective Disorders
TI  - The effect of digital interventions on attention deficit hyperactivity disorder (ADHD): A meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1016%2fj.jad.2024.08.156
VL  - 365
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Tic disorder is a common neurodevelopmental disorder in childhood, characterized primarily by motor or vocal tics. However, there is no systematic evaluation of pediatric massage therapy for children with Tic disorder. This study aims to evaluate the effectiveness and safety of massage therapy for children with tic disorder through a comprehensive meta-analysis and systematic review. 

**METHODS**: We systematically searched relevant randomized controlled trials from various databases such as CBM, CNKI, VIP, Wanfang database, PubMed, Embase, Web of Science, Cochrane Library, and SINOMED, published up to October 2023. To collect randomized controlled trials on pediatric massage therapy or in combination with other therapies for the treatment of tic disorders in children. The risk of bias in the included articles was assessed using the Cochrane guideline. Meta-analyses were performed using Review Manager 5.4, and publication bias was evaluated by using Begg test and Egger test in Stata SE software. 

**RESULTS**: This meta-analysis included 19 randomized controlled trials with 1423 patients. Pediatric massage therapy alone or in combination with conventional medication demonstrated a significant increase in clinical effectiveness rates [risk ratios = 1.15, 95% confidence interval [CI] (1.10, 1.20), Z = 6.54, P &lt; .001], and reduced Yale Global Tie Severity Scale scores [standardized mean difference = -0.85, 95% CI (-1.50, -0.19), Z = 2.54, P = .01] and traditional Chinese medicine syndrome scores [standardized mean difference = -1.35, 95%CI (-2.08, -0.63), Z = 3.66, P = .0002]. In terms of adverse reactions, there was no statistical difference between the experimental and control groups [risk ratios = 0.26, 95% CI (0.14, 0.49), Z = 4.25, P &lt; .001]. The Begg test and Egger test results indicated no publication bias. 

**CONCLUSION**: Evidence suggests that pediatric massage therapy is effective in improving tic disorders in children.
AN  - 38518056
AU  - Wu,
AU  - J.
AU  - Yang,
AU  - F.
AU  - Wang,
AU  - Z.
AU  - Wang,
AU  - L.
AU  - Tian,
AU  - T.
AU  - Xue,
AU  - Z.
AU  - Sun,
AU  - L.
DB  - Mars 24.enl
DO  - /10.1097/MD.0000000000037568
L1  - internal-pdf://2430584302/Wu-2024-Pediatric massage therapy for treatmen.pdf
PY  - 2024
SP  - e37568
T2  - Medicine
TI  - Pediatric massage therapy for treatment of tic disorders in children: A systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.1097%2fMD.0000000000037568
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10957010/pdf/medi-103-e37568.pdf
VL  - 103
ER  -
TY  - JOUR
AB  - Introduction: Children diagnosed with autism spectrum disorder (ASD) commonly encounter difficulties in social interactions and communication, significantly affecting their overall wellbeing. One proposed strategy to address these challenges is through physical exercise interventions. This study aims to conduct a meta-analysis to assess the impact of physical exercise interventions on the social skills of children with ASD. 

Methods: To perform this meta-analysis, we followed the Preferred Reporting Items of Systematic Reviews and Meta-Analyses (PRISMA) Statement and the practical guide for transparent reporting of systematic reviews. Eligible studies included randomized controlled trials or quasi-experimental studies investigating the effects of physical exercise interventions on social skills among children with ASD. We used the standardized mean difference (SMD) to measure effect size. 

Results: Sixteen studies were included in the meta-analysis. The results indicated a significant improvement in social skills among children with ASD following physical exercise interventions (SMD = -0.54, 95% CI = [-0.63; -0.44]). The moderator analysis underscored the crucial role of age in explaining the intervention outcomes for enhancing social skills, with interventions lasting more than 12 weeks recommended for better social skills improvement. 

Discussion: The findings of this meta-analysis provide robust evidence supporting the efficacy of physical exercise interventions in enhancing the social skills of children with ASD. The moderator analysis underscores the importance of considering both the mean age and duration of interventions when implementing such programs. These results underscore the significance of physical exercise as a viable option for improving social skills in this population.
AN  - 39421839
AU  - Koh,
AU  - S.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fpsyg.2024.1399902
L1  - internal-pdf://1671886829/Koh-2024-Analyzing the influence of physical e.pdf
PY  - 2024
SP  - 1399902
T2  - Frontiers in Psychology
TI  - Analyzing the influence of physical exercise interventions on social skills in children with autism spectrum disorder: insights from meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffpsyg.2024.1399902
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11484040/pdf/fpsyg-15-1399902.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - **Background**
Numerous interventions for irritability in autism spectrum disorder (ASD) have been investigated. We aimed to appraise the magnitude of pharmacological and non-pharmacological interventions for irritability in ASD without any restrictions in terms of eligible interventions.

**Methods**
We systematically searched PubMed/MEDLINE, Scopus, and Web of Science until April 15, 2023. We included randomized controlled trials (RCTs) with a parallel design that examined the efficacy of interventions for the treatment of irritability in patients of any age with ASD without any restrictions in terms of eligible interventions. We performed a random-effects meta-analysis by pooling effect sizes as Hedges&rsquo; g. We classified assessed interventions as follows: pharmacological monotherapy, risperidone plus adjuvant therapy versus risperidone monotherapy, non-pharmacological intervention, and dietary intervention. We utilized the Cochrane tool to evaluate the risk of bias in each study and the GRADE approach to assess the certainty of evidence for each meta-analyzed intervention.

**Results**
Out of 5640 references, we identified 60 eligible articles with 45 different kinds of interventions, including 3531 participants, of which 80.9% were males (mean age [SD]&thinsp;=&thinsp;8.79 [3.85]). For pharmacological monotherapy, risperidone (Hedges&rsquo; g &minus;&thinsp;0.857, 95% CI &minus;&thinsp;1.263 to &minus;&thinsp;0.451, certainty of evidence: high) and aripiprazole (Hedges&rsquo; g &minus;&thinsp;0.559, 95% CI &minus;&thinsp;0.767 to &minus;&thinsp;0.351, certainty of evidence: high) outperformed placebo. Among the non-pharmacological interventions, parent training (Hedges&rsquo; g &minus;&thinsp;0.893, 95% CI &minus;&thinsp;1.184 to &minus;&thinsp;0.602, certainty of evidence: moderate) showed a significant result. None of the meta-analyzed interventions yielded significant effects among risperidone&thinsp;+&thinsp;adjuvant therapy and dietary supplementation. However, several novel molecules in augmentation to risperidone outperformed risperidone monotherapy, yet from one RCT each.

**Limitations**
First, various tools have been utilized to measure the irritability in ASD, which may contribute to the heterogeneity of the outcomes. Second, meta-analyses for each intervention included only a small number of studies and participants.

**Conclusions**
Only risperidone, aripiprazole among pharmacological interventions, and parent training among non-pharmacological interventions can be recommended for irritability in ASD. As an augmentation to risperidone, several novel treatments show promising effects, but further RCTs are needed to replicate findings.

Trial registration PROSPERO, CRD42021243965.
AN  - WOS:001157321000001
AU  - Choi,
AU  - H.
AU  - Kim,
AU  - J.
AU  - H.
AU  - Yang,
AU  - H.
AU  - S.
AU  - Kim,
AU  - J.
AU  - Y.
AU  - Cortese,
AU  - S.
AU  - Smith,
AU  - L.
AU  - Koyanagi,
AU  - A.
AU  - Dragioti,
AU  - E.
AU  - Radua,
AU  - J.
AU  - Fusar-Poli,
AU  - P.
AU  - Shin,
AU  - J.
AU  - I.
AU  - Cheon,
AU  - K.
AU  - A.
AU  - Solmi,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1186/s13229-024-00585-6
L1  - internal-pdf://3503297511/Choi-2024-Pharmacological and non-pharmacologi.pdf
PY  - 2024
SP  - 14
T2  - Molecular Autism
TI  - Pharmacological and non-pharmacological interventions for irritability in autism spectrum disorder: a systematic review and meta-analysis with the GRADE assessment
UR  - &lt;Go to ISI&gt;://WOS:001157321000001
UR  - https://molecularautism.biomedcentral.com/counter/pdf/10.1186/s13229-024-00585-6.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - <b>Background</b>: Attention-deficit/hyperactivity disorder (ADHD) is one of the common neurodevelopmental disorders in children and virtual reality (VR) has been used in the diagnosis and treatment of ADHD. 

Objective: This paper aims to systematically evaluate the effect of VR technology on the attention and motor ability of children with ADHD. 

Methods: The intervention method of the experimental group was VR technology, while the control group adopted non-VR technology. The population was children with ADHD. The outcome indicators were attention and motor abilities. The experimental design was randomized controlled trial. Two researchers independently searched PubMed, Cochrane Library, Web of Science, and Embase for randomized controlled trials related to the effect of VR technology on ADHD children&#039;s attention and motor ability. The retrieval date was from the establishment of each database to January 4, 2023. The PEDro scale was used to evaluate the quality of the included literature. Stata (version 17.0; StataCorp LLC) was used for effect size combination, forest map-making, subgroup analyses, sensitivity analyses, and publication bias. GRADEpro (McMaster University and Evidence Prime Inc) was used to evaluate the level of evidence quality. 

Results: A total of 9 literature involving 370 children with ADHD were included. VR technology can improve ADHD children&#039;s attention (Cohen d=-0.68, 95% CI -1.12 to -0.24; P&lt;.001) and motor ability (Cohen d=0.48, 95% CI 0.16-0.80; P&lt;.001). The intervention method and diagnosis type for VR technology had a moderating effect on the intervention&#039; impact on children&#039;s attention (P&lt;.05). The improvement in children&#039;s attention by &quot;immersive&quot; VR technology was statistically significant (Cohen d=-1.05, 95% CI -1.76 to -0.34; P=.004). The improvement of children&#039;s attention by &quot;nonimmersive&quot; VR technology was statistically significant (Cohen d=-0.28, 95% CI -0.55 to -0.01; P=.04). VR technology had beneficial effects on both children with an &quot;informal diagnosis&quot; (Cohen d=-1.47, 95% CI -2.35 to -0.59; P=.001) and those with a &quot;formal diagnosis&quot; (Cohen d=-0.44, 95% CI -0.85 to -0.03; P=.03). 

Conclusions: VR technology can improve attention and motor ability in children with ADHD. Immersive VR technology has the best attention improvement effect for informally diagnosed children with ADHD.https://www.crd.york.ac.uk/PROSPERO/.
AN  - 39602820
AU  - Yu,
AU  - C.
AU  - Wang,
AU  - C.
AU  - Xie,
AU  - Q.
AU  - Wang,
AU  - C.
DB  - Desember 2024.enl
DO  - /10.2196/56918
L1  - internal-pdf://4180869493/065e9931-50b7-4e33-ad5d-edf3169920fa.pdf
PY  - 2024
SP  - e56918
T2  - JMIR Serious Games
TI  - Effect of Virtual Reality Technology on Attention and Motor Ability in Children With Attention-Deficit/Hyperactivity Disorder: Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.2196%2f56918
VL  - 12
ER  -
TY  - JOUR
AB  - OBJECTIVE: This systematic review, performed in accordance with the PRISMA guidelines, seeks to summarize the interventions that have been developed in order to improve executive functioning and attention in children born prematurely. 

METHODS: The PICOS framework helped guide the structure and relevant terms selected for the study. Electronic systematic searches of the databases PubMed (NLM), Ovid Medline, Ovid All EBM Reviews, Ovid Embase, and Ovid PsycINFO were completed in March 2022. This review focuses on interventions that target attention and executive functioning in prematurely born children between birth and 12 years old, with outcome measures assessed between 3 and 12 years old, even if the age range in the study can exceed our own parameters. Data extraction included sample characteristics, country of recruitment, type of intervention, description of the intervention group and control group, outcome measures, and overall results. An assessment of the quality of methodology of studies was performed through an adaptation of the Downs and Black checklist for both randomized and nonrandomized studies in healthcare interventions. An assessment of the risk of bias was also presented using the Cochrane risk of bias tool for randomized trials 2.0. 

RESULTS: A total of 517 premature children received an intervention at some point between birth and early adolescence. Eleven different interventions were assessed in 17 studies, with rating of the quality of methodology and outcomes ranging from lower quality studies (44% quality rating) to robust studies (96% quality rating) in terms of reporting standards, external and internal validity, and power. Five of those studies focused on interventions administered in the neonatal intensive care unit or shortly postdischarge (e.g., the Mother-Infant Transaction Program and the Newborn Individualized Developmental Care and Assessment Program, documented in two articles each [11%] or the Infant Behavioral Assessment and Intervention Program assessed in one study [about 5%]), while 12 articles reported on interventions administered between the ages of 1.5-12 years old [mostly computerized cognitive training programs such as Cogmed (23%) and BrainGame Brian (17%)]. Of the 17 articles examined, 12 (70%) showed positive short-term outcomes postintervention and 3 (17%) demonstrated positive long-term results with small to large effect sizes (0.23-2.3). Among included studies, 50% showed an overall high risk of bias, 21.4% showed some concerns, and 28.6% were low risk of bias.

CONCLUSIONS: Due to the heterogeneity of the programs reviewed, the presented findings should be interpreted as descriptive results. A careful and individualized selection from the various available interventions should be made based on the target population (i.e., age at intervention administration and outcome testing) before implementing these program protocols in clinical settings.
AN  - 39186682
AU  - Maalouf,
AU  - Y.
AU  - Provost,
AU  - S.
AU  - Gaudet,
AU  - I.
AU  - Dodin,
AU  - P.
AU  - Paquette,
AU  - N.
AU  - Gallagher,
AU  - A.
DB  - August 2024.enl
DO  - /10.1093/jpepsy/jsae068
L1  - internal-pdf://1263886760/Maalouf-2024-Executive and attentional functio.pdf
PY  - 2024
SP  - 26
T2  - Journal of Pediatric Psychology
TI  - Executive and attentional functioning interventions in preterm children: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1093%2fjpepsy%2fjsae068
UR  - https://watermark.silverchair.com/jsae068.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA3AwggNsBgkqhkiG9w0BBwagggNdMIIDWQIBADCCA1IGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMgNh7oLwxGqd7Qm3GAgEQgIIDI1kvFpfMcanYFNpm6Cv4fYGWwaW6C1AuxE-m9pJ7hVZl4msvu9fhGrloOq9t6O6jnQ-H2qpJXSr_P7oh6ENNTFe5U4uo6PsAJlzHWqWaIs4SkE91R2klSp2euvkc3aJD6lEUwQehZtVFMsYiuPCyXqW0rtEJDCnXE4hXuj5r7mH93mSQOzDahd5kN8vWHmDPaWoqwhts2LP3Kp6JhCKKnoMBrcCuk4YSw6YQd7VKwruBHFDqmUXgMpvBC2c9YbuBEhFGTvAYmHRCDfOH4QmAdxWJOsM9rB1InheYnTS6bYI_ipYS8UO8x6vjwoVMWPkFgOsgYOaVkSox0JzP8J_P6_167ONA5l7CfmIdZHpVJ2K6NahEndIevD8G7JxS0Bz4w-nj12TNru6CJbMJjr1au7YB12ZJVLNucb9_Pxl1vTHuVSX6U78OTGR5wUXADQuVwLbI4SMi_RWnI-qZDAhnYZluk2zhu66z0jG5UBZeAXKzGGCK-BWxk80FOqv9_winGek3Ax8lRMhrGfxRLXa7tc3YmdwihbO7lynZ9hcyYgAZffrGONsYey5bTA3_v9hLiTyW80teuO3rCfCefPthoPJlrP8ZHOejgvc3fNoVvCa8kz3epaXQLf2yGs69_bfST8Mreqtqn2W_MmQJZhs70ve9Zbf8kfbCx-dKBRK7UmYHXu9DefK2IUhYoHnQeaRO-9g4R5t0IotoES4Zyjtp_Qh_7DIvqDCL8XlGiHO9gfLhpsM-dD6lUrss8WolEHdFQHC-edUo2Rvy173FskWwU2Aqhw7NSfCeYrt0LONn8vdsnxOsxBVuouayxT1WJzxG9NDXRfodLtr9jBRJjX-2jVs__jWNvH_kd4Eyhu964bGDHwL-i0nKVhKXyGrEPW8qdtQZyLb5aJ-NaS8LpuDhY-GHHG_KbARs9fdGPcMM1G7PQ-2FKJ02UlVtkL8e4X3hpGvxfSklFRoZvZcBlDYVfr74bb98t7JRU9xbA0FNZ9833EsO_2SE-8IiRn9b7nHcEcabcTxxXzFWMMfIyoOU4Lg-u7xO92pUAi8f1sSJ7vkXn85-
VL  - 26
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Recently, studies on behavioral interventions for autism have gained popularity. Naturalistic Developmental Behavior Interventions (NDBIs) are among the most effective, evidence-based, and widely used behavior interventions for autism. However, no research has been conducted on which of the several NDBI methods is most effective for parents and children with autism spectrum disorders. Therefore, we conducted a network meta-analysis to compare the specific effects of each type of parental-mediated NDBI on children&#039;s developmental skills and parent fidelity. 

**METHODS**: PubMed, Embase, Cochrane Library, Medline, Web of Science, China National Knowledge Infrastructure (CNKI), CINAHL, and Wanfang databases were searched from inception to August 30, 2023. A total of 32 randomized controlled trial studies that examined the efficacy of different NDBIs were included. 

**RESULTS**: Parents of children with ASD who received Pivotal Response Treatment (PRT) reported significant improvements in their children&#039;s social skills (SUCRA, 74.1%), language skills (SUCRA, 88.3%), and parenting fidelity (SUCRA, 99.5%). Moreover, parents who received Early Start Denver Model (ESDM) reported significant improvements in their children&#039;s language (SMD = 0.41, 95% CI: 0.04, 0.79) and motor skills (SMD = 0.44, 95% CI: 0.09, 0.79). In terms of the efficacy of improving parent fidelity, the results showed that the Improving Parents as Communication Teachers (ImPACT) intervention significantly improved parent fidelity when compared with the treatment-as-usual group (TAU) (SMD = 0.90, 95% CI: 0.39, 1.42) and the parental education intervention (PEI) (SMD = 1.10, 95% CI:0.28, 1.91). There was a difference in parent fidelity among parents who received PRT(SMD = 3.53, 95% CI: 2.26, 4.79) or ESDM(SMD = 1.42, 95% CI: 0.76, 2.09) training compared with PEI. 

**CONCLUSION**: In conclusion, this study revealed that parents can achieve high fidelity with the ImPACT intervention, and it can serve as an early first step for children newly diagnosed with ASD. It also showed that parent-mediated ESDM is effective in improving language and motor skills for children with ASD and can be used as part of the second stage of parent training. Parent-mediated PRT can also be used as a third stage of parent training with sufficient training intensity to further improve language, social, and motor skills.
AN  - 38664754
AU  - Ouyang,
AU  - Y.
AU  - Feng,
AU  - J.
AU  - Wang,
AU  - T.
AU  - Xue,
AU  - Y.
AU  - Mohamed,
AU  - Z.
AU  - A.
AU  - Jia,
AU  - F.
DB  - April 24.enl
DO  - /10.1186/s12887-024-04752-9
L1  - internal-pdf://0161163194/Ouyang-2024-Comparison of the efficacy of pare.pdf
PY  - 2024
SP  - 270
T2  - BMC Pediatrics
TI  - Comparison of the efficacy of parent-mediated NDBIs on developmental skills in children with ASD and fidelity in parents: a systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1186%2fs12887-024-04752-9
UR  - https://bmcpediatr.biomedcentral.com/counter/pdf/10.1186/s12887-024-04752-9.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - The sexual abuse of the child is a wide-ranging and complex problem with physical, emotional and psychological consequences, with social, moral, cultural and legal dimensions, and when the prevalence rates are analyzed, it is seen that it is a serious problem for all societies. One of the most common strategies used to prevent child sexual abuse is school-based initiatives. So, the purpose of this integrative literature review is to systematically evaluate the evidence of the effectiveness of school-based child sexual abuse prevention programs. In this context, the current study includes 22 articles that meet the criteria for inclusion. The Comprehensive Meta-Analysis (CMA) statistical program was used to calculate the effect sizes of the studies included in the meta-analysis. The mean, standard deviation, sample size, p, t, or f value data reported in the primary studies were used to calculate the effect sizes of the studies included in the meta-analysis. As a result of the analyzes carried out within the scope of the study, it was concluded that school-based education practices aimed at preventing child sexual abuse are highly effective, and that after the prevention programs, the knowledge and skill levels of the children increased widely and these increases were statistically significant. As a result, it can be said that the knowledge and self-protection skills of children can be increased by participating in school-based sexual abuse prevention programs.
AN  - WOS:001155590300001
AU  - T&uuml;rkkan,
AU  - T.
AU  - Odaci,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.16986/huje.2024.514
L1  - internal-pdf://2044878945/T&uuml;rkkan-2024-Assessment of Effectiveness of Sc.pdf
PY  - 2024
SP  - 146-162
T2  - Hacettepe Universitesi Egitim Fakultesi Dergisi-Hacettepe University Journal of Education
TI  - Assessment of Effectiveness of School-Based Child Sexual Abuse Prevention Programs: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001155590300001
VL  - 39
ER  -
TY  - JOUR
AB  - Many young people are exposed to risk factors that increase their risk of mental illness. Physical activity provision is an increasingly popular approach to protect against mental illness in the face of these risk factors. We examined the effectiveness of physical activity interventions for the promotion of mental health outcomes in at-risk children and adolescents. We searched health databases for randomised and non-randomised intervention studies, with no date restriction, and assessed risk of bias using the Cochrane Risk of Bias tools. We present a narrative synthesis of our results accompanied with a summary of available effect sizes. Thirty-seven reports on 36 studies were included, with multi-sport or yoga interventions the most popular intervention approaches (a combined 50% of included studies). Outcomes measured included internalising, self-evaluative, wellbeing, overall symptomatology, resilience, externalising, and trauma outcomes. We found that 63% of between-groups effects favoured the intervention arm, and 83% of within-groups effects favoured an intervention effect. While recognising high risk of bias, our findings provide evidence in support of the effectiveness of physical activity interventions for promoting mental health outcomes in at-risk young people. We encourage further work designed to better understand the intervention characteristics that may lead to positive benefits.
AN  - 39162060
AU  - Simpson,
AU  - A.
AU  - Teague,
AU  - S.
AU  - Kramer,
AU  - B.
AU  - Lin,
AU  - A.
AU  - Thornton,
AU  - A.
AU  - L.
AU  - Budden,
AU  - T.
AU  - Furzer,
AU  - B.
AU  - Jeftic,
AU  - I.
AU  - Dimmock,
AU  - J.
AU  - Rosenberg,
AU  - M.
AU  - Jackson,
AU  - B.
DB  - August 2024.enl
DO  - /10.1080/17437199.2024.2391787
L1  - internal-pdf://3157221675/Simpson-2024-Physical activity interventions f.pdf
PY  - 2024
SP  - 1-35
T2  - Health Psychology Review
TI  - Physical activity interventions for the promotion of mental health outcomes in at-risk children and adolescents: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1080%2f17437199.2024.2391787
UR  - https://www.tandfonline.com/doi/pdf/10.1080/17437199.2024.2391787
ER  -
TY  - JOUR
AB  - BACKGROUND: Children with disabilities (CWDs) constitute a substantial segment of the population who encounter abuse, emphasizing the need to comprehend the influence of school-based interventions on this susceptible group. <b>AIM</b>: This systematic review and meta-analysis aimed to identify and evaluate the effectiveness of school-based interventions in enhancing child sexual abuse (CSA) knowledge among CWDs. 

PARTICIPANTS: This meta-analysis incorporated seven published studies, encompassing 387 CWDs. 

METHODS: Our study synthesizes findings from seven experimental and quasi-experimental studies, adhering to the PRISMA guidelines. The study was registered in PROSPERO. The literature search, conducted between September 25, 2023, and October 2, 2023, employed various databases and keywords relevant to the study&#039;s scope. The research question and articles&#039; eligibility were assessed using the Population, Intervention, Comparison, Outcomes, and Study type (PICOs). The meta-analysis was conducted using the Comprehensive Meta-Analysis (CMA) software. 

RESULTS: The school-based intervention greatly impacted CWDs&#039; CSA knowledge scores (Hedges&#039;s g = 1.026 [95% CI: 0.845; 1.208], z = 11.074, p = 0.000). The findings of this meta-analysis demonstrate that Questionnaire/scale-based knowledge measurement (Hedges&#039;s g = 2.586 [95% CI: 0.920; 4.252], z = 3.043, P = 0.002) and Vignette-based knowledge measurement (Hedges&#039;s g = 1.065 [95% CI: 0.655; 1.474], z = 5.100, p = 0.000) are effective in assessing CWDs&#039; knowledge of CSA. 

CONCLUSION: This systematic review and meta-analysis of seven randomized controlled studies and quasi-experimental studies provide robust evidence supporting the effectiveness of school-based interventions in significantly enhancing CSA knowledge among CWDs. <b>IMPLICATIONS TO PRACTICE</b>: These findings are potentially significant evidence for education professionals, including educators and school health nurses.
AN  - 38955613
AU  - Ozcevik
AU  - Subasi,
AU  - D.
AU  - Akca
AU  - Sumengen,
AU  - A.
AU  - Semerci,
AU  - R.
AU  - Cakir,
AU  - G.
AU  - N.
DB  - Juli 2024.enl
DO  - /10.1016/j.pedn.2024.06.024
L1  - internal-pdf://3044293449/1-s2.0-S0882596324002525-main.cleaned.pdf
PY  - 2024
SP  - 01
T2  - Journal of Pediatric Nursing
TI  - Effectiveness of school-based interventions on child sexual abuse knowledge in children with disabilities: Systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.pedn.2024.06.024
VL  - 01
ER  -
TY  - JOUR
AB  - To compare the effects of single aerobic exercise, cognitive + exercise, combined exercise, and ball exercise on inhibitory control in children with attention deficit hyperactivity disorder (ADHD) using network Meta-analysis. Literature related to randomized controlled trials of exercise interventions for inhibitory control in children with ADHD was searched in the databases of pubmed, Web of science, Embase, Cochrane, and Scopus with a search deadline of December 31, 2023. Two researchers screened the literature, extracted data, and evaluated methodological quality. Statistical analysis and plotting were performed using Stata 17.0 software. A total of 18 papers involving 737 participants were included. Network Meta-analysis showed that single aerobic exercise [SMD = 0.75 (0.27,1.22), P &lt; 0.05], ball games [SMD = 1.98 (0.99,2.97), P &lt; 0.05] were significantly better than the control group, and ball games were significantly better than the combination exercises [SMD = 1.66(0.50,2.81), P &lt; 0.05], cognitive + exercise [SMD = 1.69(0.46,2.92), P &lt; 0.05], single aerobic exercise[SMD = 1.23(0.13,2.33), P &lt; 0.05]. The results of SUCRA probability ranking showed that ball exercises played the most significant role in improving inhibitory control (SUCRA = 99.5). Single aerobic and ball sports have significant advantages in inhibitory control in children with ADHD; ball sports are significantly better than combined exercises, single aerobic exercise, and cognitive + exercise in inhibitory control in children with ADHD. Ball games are the most effective intervention in enhancing inhibitory control in children with ADHD.
AN  - WOS:001314903600001
AU  - Li,
AU  - H.
AU  - Zhang,
AU  - P.
AU  - Yan,
AU  - B.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1007/s12144-024-06661-7
L1  - internal-pdf://1033959920/Li-2024-Does type of exercise matter_ Network.pdf
PY  - 2024
SP  - 10
T2  - Current Psychology
TI  - Does type of exercise matter? Network meta-analysis of the effects of different exercise modalities on inhibitory control in children with attention deficit hyperactivity disorder
UR  - &lt;Go to ISI&gt;://WOS:001314903600001
UR  - https://link.springer.com/article/10.1007/s12144-024-06661-7
UR  - https://link.springer.com/content/pdf/10.1007/s12144-024-06661-7.pdf
ER  -
TY  - JOUR
AB  - To investigate the impact of different types of exercise modalities on children and adolescents with developmental disorders. Data were obtained from randomized controlled trials retrieved from five databases. Following the PRISMA NMA guidelines, a Bayesian framework-based Markov chain Monte Carlo simulation was used for aggregation and analysis. The included studies were assessed for risk of bias and quality evaluation. A total of 68 studies were included. Moderate-quality evidence suggests that combative sports may be the best exercise for enhancing gross motor skills, ball sports are the most effective for improving executive function, neurodevelopmental motor training is the most effective for improving social skills, and aquatic exercise is the most effective for improving behavioral problems.

 CONCLUSIONS: Combat sports, ball sports, neurodevelopmental motor training, and aquatic exercise may be effective exercise modalities for improving symptoms in children and adolescents with developmental disorders. However, the degree of improvement can vary among individuals with specific developmental disorders. Therefore, precise assessment of the individual symptoms of children or adolescents is crucial before selecting specific exercise interventions. <b>TRIAL REGISTRATION</b>: PROSPERO (CRD42024545673).

 WHAT IS KNOWN: * Many studies indicate that exercise as an intervention can have positive effects on individuals with developmental disorders, such as ADHD and autism. However, reported effects vary, and there is no clear consensus on the optimal exercise intervention method yet.

WHAT IS NEW: * Through a comprehensive network meta-analysis, various exercise interventions for children and adolescents with developmental disorders were compared to determine the optimal approach. The study found that combat sports, ball sports, neurodevelopmental motor training, and aquatic exercise could potentially be effective modalities for improving symptoms in this population.
AN  - 39546034
AU  - Jia,
AU  - M.
AU  - Hu,
AU  - F.
AU  - Yang,
AU  - D.
DB  - November 2024.enl
DO  - /10.1007/s00431-024-05858-z
L1  - internal-pdf://2752347347/s00431-024-05858-z.cleaned.pdf
PY  - 2024
SP  - 18
T2  - European Journal of Pediatrics
TI  - Effects of different exercise modalities on pediatric and adolescent populations with developmental disorders: a network meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1007%2fs00431-024-05858-z
UR  - https://link.springer.com/article/10.1007/s00431-024-05858-z
VL  - 184
ER  -
TY  - JOUR
AB  - BACKGROUND: Previous research indicates disparities in the care of bereaved parents and siblings following a stillbirth in the family. The aim of this systematic review was to assess the effects of interventions aimed at reducing psychological distress among parents or siblings in high-income countries after experiencing a stillbirth. 

METHODS: The databases CINAHL, Medline, PsycInfo, Cochrane Library, and EMBASE were searched in August 2022. 

RESULTS: Four intervention studies from the United States (US), the United Kingdom (UK), Finland, and Australia, met the inclusion criteria. The interventions comprised a perinatal grief support team; a perinatal counselling service; a grief support program; and a support package including contacts with peer supporters and health care staff. No studies of interventions for siblings were found. The results could not be synthesised due to disparities in interventions and outcome measures. The risk of bias was assessed as high in all four studies and the certainty for all outcomes was rated as very low. 

CONCLUSION: More controlled trials with rigorous methods are needed to evaluate the effect of bereavement support interventions in parents and siblings after stillbirth. Future studies should include a core outcome set to make them more comparable. Most of the studies in this review were assessed to have an overall high risk of bias, mainly due to problems with missing outcome data; thus, future studies could specifically target this problem.
AN  - 38242808
AU  - Hildingsson,
AU  - I.
AU  - Bertero,
AU  - C.
AU  - Hultcrantz,
AU  - M.
AU  - Karrman
AU  - Fredriksson,
AU  - M.
AU  - Peira,
AU  - N.
AU  - Silverstein,
AU  - R.
AU  - A.
AU  - Persson,
AU  - M.
AU  - Sveen,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.wombi.2024.01.007
L1  - internal-pdf://2150464771/1-s2.0-S1871519224000192-main.pdf
PY  - 2024
SP  - 18
T2  - Women &amp; Birth: Journal of the Australian College of Midwives
TI  - Support interventions to reduce psychological distress in families experiencing stillbirth in high income countries: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38242808
UR  - https://www.sciencedirect.com/science/article/pii/S1871519224000192?via%3Dihub
VL  - 18
ER  -
TY  - JOUR
AB  - Interventions utilizing human-computer interaction (HCI) in autism rehabilitation have gained popularity, yet their efficacy has not been fully elucidated. This meta-analysis assessed 30 international studies from the past decade that employed HCIs for autism intervention. The findings revealed a moderate positive effect (g = 0.484) on improving social skills, reducing repetitive behaviors, and mitigating emotional disturbances in individuals with autism. Common HCI technologies, such as applications, robots, and virtual reality, exhibit moderate effects. Adult participants benefitted the most, followed by adolescents, children, and infants. This discrepancy may be related to the stability and engagement of adults in terms of cognition and behavior. Individual-format interventions surpass group formats, and interventions lasting less than one month tend to be more focused and goal-oriented, demonstrating the most significant effects on ASD. Furthermore, research findings indicate no publication bias; however, due to the variability among individuals with ASD and the diversity of intervention measures, further analysis is needed to identify the underlying factors influencing the effectiveness of these interventions.
AN  - WOS:001330208700003
AU  - Liu,
AU  - Y.
AU  - F.
AU  - Ma,
AU  - Y.
AU  - Huang,
AU  - L.
AU  - B.
AU  - Xiao,
AU  - C.
AU  - L.
AU  - Ding,
AU  - T.
DB  - November 2024.enl
DO  - 10.1007/s10639-024-13096-x
L1  - internal-pdf://1195472522/s10639-024-13096-x.cleaned.pdf
PY  - 2024
SP  - 20
T2  - Education and Information Technologies
TI  - The effects of human-computer interaction-based interventions for autism spectrum disorder: a meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001330208700003
UR  - https://link.springer.com/article/10.1007/s10639-024-13096-x
ER  -
TY  - JOUR
AB  - Solution-focused brief therapy (SFBT) can be a culturally adaptive school-based intervention for youth. Despite the evidence that supports the practical use of SFBT with various populations, its effectiveness particularly among East Asian American (EAA) youth outcomes in school settings requires further study. For this systematic review and meta-analysis, we searched U.S. and East Asian studies (e.g., Chinese, Korean, and Japanese) published from 1995 to 2022 and compared the treatment effects of SFBT on youth outcomes. This study looked at results from 110 studies from the U.S., Chinese, and Korean literatures and revealed stronger treatment effects of SFBT in Chinese and Korean studies compared with U.S. studies. The moderation effects of country showed that the overall treatment effect size was greater among Korean studies compared with U.S. studies. Implications for the use of SFBT among EAA youth are discussed.
AN  - WOS:001236457400001
AU  - Park,
AU  - I.
AU  - Y.
AU  - Kim,
AU  - J.
AU  - Franklin,
AU  - C.
AU  - Zhang,
AU  - A.
AU  - A.
AU  - Guz,
AU  - S.
AU  - Shinohara,
AU  - T.
AU  - Yu,
AU  - M.
AU  - Cho,
AU  - Y.
AU  - J.
AU  - Hai,
AU  - A.
AU  - H.
DB  - Juni 24.enl
DO  - 10.1177/10443894241234089
L1  - internal-pdf://4214517111/park-et-al-2024-comparing-the-effectiveness-of.pdf
PY  - 2024
SP  - 21
T2  - Families in Society-the Journal of Contemporary Social Services
TI  - Comparing the Effectiveness of Solution-Focused Brief Therapy for Adolescent Outcomes in Schools Between the US and East Asian Studies: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001236457400001
UR  - https://journals.sagepub.com/doi/10.1177/10443894241234089
ER  -
TY  - JOUR
AB  - Background: Consistent diabetes control is crucial for patients with type 1 diabetes (T1D) to prevent diabetic complications. Analyzing the long-term effects of non-pharmacological interventions can improve diabetes management. 

Aim: To examine the long-term effects of non-pharmacological interventions in adolescents and young adults with T1D through a systematic review and meta-analysis of randomized controlled trials (RCTs). 

Methods: The searches, without any year limitations, were conducted in seven databases. Two reviewers independently performed data extraction and risk of bias assessments. The meta-analysis was conducted using the RevMan 5.4 program and R Studio. The study was registered with PROSPERO (CRD42024503185). 

Results: A total of 40 studies were included in the systematic review, of which 28 were included in the meta-analysis. Notably, non-pharmacological interventions were effective in improving glycated hemoglobin (HbA1c) at 6 months and self-care at &gt;12 months of follow-up. Subgroup analyses revealed that combined interventions encompassing self-care behavior management, education, and psychological interventions could enhance self-care. Additionally, a combination of face-to-face and telephonic communication was effective in improving HbA1c.
AN  - WOS:001358384200001
AU  - Lee,
AU  - D.
AU  - Lee,
AU  - H.
AU  - Lee,
AU  - M.
AU  - Park,
AU  - G.
DB  - November 2024.enl
DO  - 10.1111/wvn.12751
L1  - internal-pdf://2691202056/Lee-2024-Long-term effects of non-pharmacologi.pdf
PY  - 2024
SP  - 13
T2  - Worldviews on Evidence-Based Nursing
TI  - Long-term effects of non-pharmacological interventions in adolescents and young adults with type 1 diabetes: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001358384200001
ER  -
TY  - JOUR
AB  - Background: Accelerated by technological advancements and the recent global pandemic, there is burgeoning interest in digital mental health literacy (DMHL) interventions that can positively affect mental health. However, existing work remains inconclusive regarding the effectiveness of DMHL interventions. Objective: This systematic review and meta -analysis investigated the components and modes of DMHL interventions, their moderating factors, and their long-term impacts on mental health literacy and mental health. Methods: We used a random -effects model to conduct meta -analyses and meta -regressions on moderating effects of DMHL interventions on mental health. Results: Using 144 interventions with 206 effect sizes, we found a moderate effect of DMHL interventions in enhancing distal mental health outcomes (standardized mean difference=0.42, 95% CI -0.10 to 0.73; P&lt;.001) and a large effect in increasing proximal mental health literacy outcomes (standardized mean difference=0.65, 95% CI 0.59-0.74; P&lt;.001). Uptake of DMHL interventions was comparable with that of control conditions, and uptake of DMHL interventions did not moderate the effects on both proximal mental health literacy outcomes and distal mental health outcomes. DMHL interventions were as effective as face-to-face interventions and did not differ by platform type or dosage. DMHL plus interventions (DMHL psychoeducation coupled with other active treatment) produced large effects in bolstering mental health, were more effective than DMHL only interventions (self-help DMHL psychoeducation), and were comparable with non-DMHL interventions (treatment as usual). DMHL interventions demonstrated positive effects on mental health that were sustained over follow-up assessments and were most effective in enhancing the mental health of emerging and older adults. Conclusions: For theory building, our review and meta -analysis found that DMHL interventions are as effective as face-to-face interventions. DMHL interventions confer optimal effects on mental health when DMHL psychoeducation is combined with informal, nonprofessional active treatment components such as skills training and peer support, which demonstrate comparable effectiveness with that of treatment as usual (client -professional interactions and therapies). These effects, which did not differ by platform type or dosage, were sustained over time. Additionally, most DMHL interventions are found in Western cultural contexts, especially in high -income countries (Global North) such as Australia, the United States, and the United Kingdom, and limited research is conducted in low-income countries in Asia and in South American and African countries. Most of the DMHL studies did not report information on the racial or ethnic makeup of the samples. Future work on DMHL interventions that target racial or ethnic minority groups, particularly the design, adoption, and evaluation of the effects of culturally adaptive DMHL interventions on uptake and mental health functioning, is needed. Such evidence can drive the adoption and implementation of DMHL interventions at scale, which represents a key foundation for practice -changing impact in the provision of mental health resources for individuals and the community.
AN  - WOS:001183554900003
AU  - Yeo,
AU  - G.
AU  - Reich,
AU  - S.
AU  - M.
AU  - Liaw,
AU  - N.
AU  - A.
AU  - Chia,
AU  - E.
AU  - Y.
AU  - M.
DB  - April 24.enl
DO  - 10.2024/1/e51268
L1  - internal-pdf://2306440556/PDF.cleaned (3).pdf
PY  - 2024
SP  - 19
T2  - Journal of Medical Internet Research
TI  - The Effect of Digital Mental Health Literacy Interventions on Mental Health: Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001183554900003
VL  - 26
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: This systematic review aims to evaluate the effectiveness of universal school-based transdiagnostic interventions in promoting the mental health of children and adolescents. It compares and discusses interventions targeting the prevention of mental disorders versus the promotion of mental health. Additionally, the roles of teachers and psychologists as intervention conductors are examined. 

**METHODS**: A comprehensive search of the Psycinfo, Pubmed, and Web of Science databases was conducted without any time restrictions to identify relevant literature on universal school-based transdiagnostic interventions promoting children and adolescents&#039; mental health. 

**RESULTS AND DISCUSSION**: The findings reveal that universal school-based transdiagnostic promotion/prevention programs have a small to medium overall effect size. These interventions demonstrate a broad coverage of different aspects of children and adolescents&#039; mental health. However, the relative effectiveness of teacher-led versus psychologist-led interventions remains unclear. Interventions focused on preventing mental disorders exhibit a higher effect size, albeit on a narrower range of mental health aspects for children and adolescents. 

**SIGNIFICANCE**: This study enhances our understanding of universal school-based transdiagnostic interventions and their impact on children and adolescents&#039; mental health. Further research is needed to elucidate the comparative efficacy of teacher-led and psychologist-led interventions and to explore the specific dimensions of mental health targeted by these interventions.
AN  - 38600562
AU  - Wang,
AU  - P.
AU  - Wang,
AU  - Z.
AU  - Qiu,
AU  - S.
DB  - April 24.enl
DO  - /10.1186/s13034-024-00735-x
L1  - internal-pdf://0545878561/Wang-2024-Universal, school-based transdiagnos.pdf
PY  - 2024
SP  - 47
T2  - Child &amp; Adolescent Psychiatry &amp; Mental Health [Electronic Resource]
TI  - Universal, school-based transdiagnostic interventions to promote mental health and emotional wellbeing: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.1186%2fs13034-024-00735-x
UR  - https://capmh.biomedcentral.com/counter/pdf/10.1186/s13034-024-00735-x.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - Background: Children and young people with experience of being in care (e.g. foster care, kinship care, residential care or at home with a supervision requirement order) are at higher risk of adverse mental health and well-being outcomes compared to the general population. Despite a range of policy recommendations and interventions, it is not clear what approaches are effective in the United Kingdom, or how context factors give rise to facilitators and inhibitors of implementation and acceptability. 

Objectives: The CHIMES review is a complex-systems-informed mixed-method systematic review that aimed to synthesise the international evidence base for interventions addressing the mental health and well-being of care-experienced children and young people (age &lt;= 25 years) and to assess the potential transportability of this evidence base to the United Kingdom context. 

Data sources: We searched 16 electronic bibliographic databases and 22 websites from 1990 to May 2022. We conducted citation tracking, screened relevant systematic reviews and contacted international experts. 

Method: We used a convergent synthesis design. We first constructed an evidence map to confirm review scope before undertaking method-level syntheses for outcome evaluations, process evaluations and economic evaluations. These elements were integrated into a review-level synthesis to identify potential evidence-based interventions that may progress to further development, adaptation and evaluation in the United Kingdom. We conducted stakeholder consultations to prioritise intervention theories, types and outcomes. 

Results: We identified 64 interventions from 124 study reports. Interventions were primarily evaluated in the United States and targeted young people&#039;s competencies or carers&#039; parenting practices. Meta-analysis reported limited evidence that interventions effectively improved mental health in the shorter term (0-6 months): total social, emotional and behavioural problems (d = -0.15, 95% confidence interval -0.28 to -0.02); internalising problem behaviours (d = -0.35, 95% confidence interval -0.61 to -0.08); externalising problem behaviours (d = -0.30, 95% confidence interval -0.53 to -0.08); depression and anxiety (d = -0.26, 95% confidence interval -0.40 to -0.13) and social-emotional functioning difficulties (d = -0.18, 95% confidence interval -0.31 to -0.05), but these impacts were not observed in the longer term (&gt; 6 months). Five key context factors potentially explain challenges to implementation and acceptability: lack of system resources; the time, cognitive and emotional burden of delivery or participation; interprofessional tensions; the devaluing of young people, meaning that they felt unable to express dissatisfaction with interventions; and the devaluating of carers&#039; expertise and needs. From the evidence, stakeholder consultation identified two priority interventions: (1) mentoring by individuals with knowledge and experience of care and (2) system and ethos change to create harmonisation between organisations and facilitate interprofessional relationships. Well-being and suicide-related behaviours are priority outcomes alongside mental health. 

Limitations: The review was limited by a paucity of theory and economic evaluations, so it is unclear how interventions might function or their potential cost-effectiveness. Interventions were insufficiently described, making it challenging to map the evidence base. Outcome evaluations were poorly reported. Due to ongoing restrictions with COVID-19, stakeholder consultations were conducted later than intended with a smaller number of attendees. 

Conclusions: The review identified some evidence for interventions impacting mental health in the short term. There is a lack of system-level interventions and approaches that target subjective well-being and suicide-related outcomes. Future intervention might prioritise mentoring and targeting system culture. <b>Study registration</b>: This study is registered as PROSPERO CRD42020177478.

Funding: This award was funded by the National Institute for Health and Care Research (NIHR) Public Health Research programme (NIHR award ref: NIHR129113) and is published in full in Public Health Research; Vol. 12, No. 14. See the NIHR Funding and Awards website for further award information.
AN  - 39641478
AU  - Evans,
AU  - R.
AU  - MacDonald,
AU  - S.
AU  - Trubey,
AU  - R.
AU  - Noyes,
AU  - J.
AU  - Robling,
AU  - M.
AU  - Willis,
AU  - S.
AU  - Vinnicombe,
AU  - S.
AU  - Boffey,
AU  - M.
AU  - Wooders,
AU  - C.
AU  - El-Banna,
AU  - A.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
DB  - Desember 2024.enl
DO  - /10.3310/MKYP6299
L1  - internal-pdf://2264072330/Evans-2024-Interventions to improve mental hea.pdf
PY  - 2024
SP  - 1-124
T2  - Public Health Research
TI  - Interventions to improve mental health and well-being in care-experienced children and young people aged less than 25: the CHIMES systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.3310%2fMKYP6299
UR  - https://njl-admin.nihr.ac.uk/document/download/2046707
VL  - 12
ER  -
TY  - JOUR
AB  - Despite the wide usage of technology in educational settings, the overall evidence base of technology-aided reading interventions for students with autism spectrum disorder (ASD) has not been fully investigated. The purpose of this meta-analysis was to quantify the effects of technology-aided reading interventions for students with ASD and determine if participant and intervention characteristics moderate intervention effects. Reviewed articles were systematically identified and evaluated for methodological rigor according to design standards suggested by What Works Clearinghouse (WWC). A total of 13 single-case studies that met the WWC standards (50%) were analyzed for effects using Tau-U and yielded 50 separate effect sizes with 33 participants. Results of this study found a moderate overall effect of .89 (CI95 [.83, .96]) for technology-aided reading interventions, and variables associated with using time delay moderated reading outcomes.
AN  - WOS:001289670100001
AU  - Kim,
AU  - S.
AU  - Y.
AU  - Mason,
AU  - R.
AU  - A.
AU  - Rispoli,
AU  - M.
AU  - Davis,
AU  - J.
AU  - L.
AU  - Lory,
AU  - C.
AU  - Gregori,
AU  - E.
AU  - Roberts,
AU  - C.
AU  - A.
AU  - Whitford,
AU  - D.
AU  - Wang,
AU  - D.
AU  - N.
DB  - September 2024.enl
DO  - 10.1177/10883576241267963
L1  - internal-pdf://0187586455/kim-et-al-2024-a-meta-analysis-of-single-case-.pdf
PY  - 2024
SP  - 12
T2  - Focus on Autism and Other Developmental Disabilities
TI  - A Meta-Analysis of Single-Case Research on Technology-Aided Reading Interventions for Students With Autism Spectrum Disorder
UR  - &lt;Go to ISI&gt;://WOS:001289670100001
UR  - https://journals.sagepub.com/doi/10.1177/10883576241267963
ER  -
TY  - JOUR
AB  - **Objective:** 
To compare the effects of various sports exercise programs on the core symptoms of patients with autism spectrum disorder (ASD). 

**Methods:** 
We searched the China National Knowledge Infrastructure, VIP databases, Wanfang databases, Cochrane Library, PubMed, EMBASE, and Web of Science databases from their inception to February 2023 for randomized controlled trial that investigated the effect of sports exercise on the core symptoms of ASD. The overall risk of bias in the included literature was summarized using the revised Cochrane Randomized Trial Risk of Bias Tool (ROB2), and network meta-analysis was used to compare the intervention effects. 

**Results:**
A total of 30 studies involving 1,375 participants were included. The results showed that sports exercise programs, including 8-12 weeks of ball sports (SMD = -5.35, 95%CI: -7.57, -3.23), horse riding (SMD = -3.71, 95%CI: -6.18, -1.13), 8-12 weeks of comprehensive sports exercise (SMD = -2.17, 95%CI: -3.99, -0.44), and more than 12 weeks of comprehensive sports exercise (SMD = -3.75, 95%CI: -6.33, -1.24), significantly improved social interaction disorders. Furthermore, 8-12 weeks of ball sports (SMD = -4.36, 95%CI: 2.04, 6.73) and more than 12 weeks of comprehensive sports exercise (SMD = 3.65, 95%CI: 1.40, 6.08) significantly improved repetitive behaviors and restricted interests. 

**Conclusion:** 
Sports exercise can improve the core symptoms of ASD patients, and different symptoms show a selective response to different exercise elements.
AN  - WOS:001229764700001
AU  - Li,
AU  - L.
AU  - L.
AU  - Jia,
AU  - S.
AU  - Q.
AU  - Wang,
AU  - P.
AU  - Li,
AU  - S.
AU  - F.
AU  - Wang,
AU  - X.
AU  - Zhu,
AU  - X.
AU  - Y.
DB  - Juni 24.enl
DO  - 10.3389/fneur.2024.1360434
L1  - internal-pdf://0315322188/Li-2024-A network meta-analysis of the effect.pdf
PY  - 2024
SP  - 12
T2  - Frontiers in Neurology
TI  - A network meta-analysis of the effect of physical exercise on core symptoms in patients with autism spectrum disorders
UR  - &lt;Go to ISI&gt;://WOS:001229764700001
UR  - https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1360434/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - The fast-paced, technology-driven demands of modern society give rise to heightened levels of cognitive overload and psychological fatigue which presents challenges for the cognitive health and development of young people. Beyond cognitive restoration, cognitive enhancement in childhood is a key influence on future educational, occupational, and social outcomes. One promising avenue of research relates to nature exposure and its potential to restore cognitive processes (restorative effect) and increase cognitive capacity for cognitive processing (instorative effect) in children and adolescents. This systematic review and meta-analysis sought to provide clearer insight into the body of literature surrounding the benefits of nature on cognition for children and adolescents by providing a statistical synthesis of the conflicting reports in this area. Two meta-analyses were conducted to investigate the association (from 22 correlational studies) and effect (from 34 experimental studies) of nature exposure on cognition within children and adolescents. Findings revealed no association across correlational studies but small positive restorative effects and instorative effects effect across experimental studies-particularly for attention and executive functioning outcomes. Moderator analyses indicated that lengthier interventions produced significant nature effects over shorter interventions. Additionally, both children (&lt;10 years) and adolescents (10-19 years) appeared to benefit equally from nature exposure interventions. The beneficial nature effect was observed for neurotypical youths; however, the findings for neurodivergent youths were inconclusive due to limited studies, thereby warranting further research in this population. Publication bias was not an issue, though sensitivity analyses revealed that more rigorous studies yielded smaller effect sizes than studies of lower methodological quality, indicating that findings should be taken with caution, and that stronger evidence in the investigation of nature-based restorative/instorative effects is warranted. Research in this area is critical as nature exposure appears to be a viable strategy to foster healthy cognitive development in young people.
AN  - WOS:001250587100001
AU  - Nguyen,
AU  - L.
AU  - Walters,
AU  - J.
DB  - Juli 2024.enl
DO  - 10.1016/j.jenvp.2024.102336
L1  - internal-pdf://3941219270/1-s2.0-S0272494424001099-main.cleaned.pdf
PY  - 2024
SP  - 25
T2  - Journal of Environmental Psychology
TI  - Benefits of nature exposure on cognitive functioning in children and adolescents: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001250587100001
VL  - 96
ER  -
TY  - JOUR
AB  - Background: Studies have shown that music therapy can be used as a therapeutic aid for clinical disorders. To evaluate the effects of music therapy (MT) on language communication and social skills in children with autism spectrum disorder (ASD), a meta-analysis was performed on eligible studies in this field. 

Methods: A systematic search was conducted in eight databases: PubMed, Embase, Web of Science, Cochrane Library databases, the China National Knowledge Infrastructure (CNKI), Wanfang Data, the Chinese Biomedical Literature (CBM) Database, and the VIP Chinese Science and Technology Periodicals Database. The standard mean difference (SMD) values were used to evaluate outcomes, and the pooled proportions and SMD with their 95% confidence intervals (CIs) were also calculated. 

Results: Eighteen randomized controlled trial (RCT) studies were included, with a total of 1,457 children with ASD. This meta-analysis revealed that music therapy improved their language communication [SMD = -1.20; 95%CI -1.45, -0.94; chi&lt;sup&gt;2&lt;/sup&gt; (17) = 84.17, I&lt;sup&gt;2&lt;/sup&gt; = 80%, p &lt; 0.001] and social skills [SMD = -1. 13; 95%CI -1.49, -0.78; chi&lt;sup&gt;2&lt;/sup&gt; (17) = 162.53, I&lt;sup&gt;2&lt;/sup&gt; = 90%, p &lt; 0.001]. In addition, behavior [SMD = -1.92; 94%CI -2.56, -1.28; chi&lt;sup&gt;2&lt;/sup&gt; (13) = 235.08, I&lt;sup&gt;2&lt;/sup&gt; = 95%, p &lt; 0.001], sensory perception [SMD = -1.62; 95%CI -2.17, -1.08; chi&lt;sup&gt;2&lt;/sup&gt; (16) = 303.80, I&lt;sup&gt;2&lt;/sup&gt; = 95%, p &lt; 0.001], self-help [SMD = -2. 14; 95%CI -3.17, -1.10; chi&lt;sup&gt;2&lt;/sup&gt; (6) = 173.07, I&lt;sup&gt;2&lt;/sup&gt; = 97%, p &lt; 0.001] were all improved. 

Conclusion: Music therapy has a positive effect on the improvement of symptoms in children with ASD. <b>Systematic review registration</b>: https://www.crd.york.ac.uk/PROSPERO/.
AN  - 38774719
AU  - Shi,
AU  - Z.
AU  - Wang,
AU  - S.
AU  - Chen,
AU  - M.
AU  - Hu,
AU  - A.
AU  - Long,
AU  - Q.
AU  - Lee,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fpsyg.2024.1336421
L1  - internal-pdf://1262512268/Shi-2024-The effect of music therapy on langua.pdf
PY  - 2024
SP  - 1336421
T2  - Frontiers in Psychology
TI  - The effect of music therapy on language communication and social skills in children with autism spectrum disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffpsyg.2024.1336421
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11106491/pdf/fpsyg-15-1336421.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - OBJECTIVE: To assess the effectiveness of Internet-based self-help interventions in treating depression in adolescents and young adults. 

METHODS: A systematic search was conducted across six databases, including PubMed, to identify randomized controlled trials (RCTs) that satisfied the specified inclusion and exclusion criteria. The intervention measure consisted of Internet-based self-help interventions. 

RESULTS: A total of 23 randomized controlled trials (RCTs) were included in this analysis. Meta-analysis indicated that Internet-based self-help therapies significantly reduced depression scores in adolescents and young adults. (OR = -0.68, 95%CI [-0.88, -0.47], P &lt; 0.001). We examined the effects of patient recruitment from various regions, medication usage, therapist involvement, weekly intervention time, and intervention duration. Patients selected from school, primary healthcare centers, clinics and local communities had better results. Intervention lasting 30 to 60 min and 60 to180 minutes per week were effective in the short term. 

CONCLUSION: The internet-based self-help intervention can be effective in treating depression in adolescents and young adults. However, factors such as patient recruitment locations, medication usage, Therapists&#039; involvement, weekly intervention time, and intervention duration interacted with the outcome. Subgroup analysis on potential adverse effects and gender was impossible due to insufficient data from the included studies.
AN  - 39243081
AU  - Ma,
AU  - Q.
AU  - Shi,
AU  - Y.
AU  - Zhao,
AU  - W.
AU  - Zhang,
AU  - H.
AU  - Tan,
AU  - D.
AU  - Ji,
AU  - C.
AU  - Liu,
AU  - L.
DB  - September 2024.enl
DO  - /10.1186/s12888-024-06046-x
L1  - internal-pdf://0321212593/Ma-2024-Effectiveness of internet-based self-h.pdf
PY  - 2024
SP  - 604
T2  - Bmc Psychiatry
TI  - Effectiveness of internet-based self-help interventions for depression in adolescents and young adults: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1186%2fs12888-024-06046-x
UR  - https://bmcpsychiatry.biomedcentral.com/counter/pdf/10.1186/s12888-024-06046-x.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - **Background**: Suicide is a leading cause of death among adolescents and young adults. While only few evidence-based treatments with limited efficacy are available, family processes have recently been posed as a possible alternative target for intervention. Here, we review the evidence for Attachment-Based Family Therapy (ABFT), a guideline-listed treatment targeting intrafamilial ruptures and building protective caregiver-child relationships. **Method**: PubMed, PsycINFO, Embase, and Scopus were searched for prospective trials on ABFT in youth published up until November 6(th), 2023, and including measures of suicidality. Results were independently screened by two researchers following PRISMA guidelines. Risk of bias was assessed using the Cochrane RoB-2 framework. A random effects meta-analysis was conducted on suicidal ideation and depressive symptoms post-intervention scores in randomized-controlled trials (RCTs). **Results**: Seven articles reporting on four RCTs (n = 287) and three open trials (n = 45) were identified. Mean age of participants was M-pooled = 15.2 years and the majority identified as female (similar to 80%). Overall, ABFT was not significantly more effective in reducing youth suicidal ideation, g(pooled) = 0.40, 95% CI [-0.12, 0.93], nor depressive symptoms, g(pooled) = 0.33, 95% CI [-0.18, 0.84], compared to investigated controls (Waitlist, (Enhanced) Treatment as Usual, Family-Enhanced Nondirective Supportive Therapy). **Conclusion**: Evidence is strongly limited, with few available trials, small sample sizes, high sample heterogeneity, attrition rates, and risk of bias. While not generally superior to other treatments, ABFT might still be a clinically valid option in specific cases and should be further investigated. Clinicians are currently recommended to apply caution when considering ABFT as stand-alone intervention for suicidal youth and to decide on a case-by-case basis.
AN  - WOS:001389345900005
AU  - Schulte-Frankenfeld,
AU  - P.
AU  - M.
AU  - Breedvelt,
AU  - J.
AU  - J.
AU  - F.
AU  - Brouwer,
AU  - M.
AU  - E.
AU  - van
AU  - der
AU  - Spek,
AU  - N.
AU  - Bosmans,
AU  - G.
AU  - Bockting,
AU  - C.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.32872/cpe.13717
L1  - internal-pdf://1828341333/Schulte-Franken-2024-Effectiveness of Attachme.pdf
PY  - 2024
SP  - 23
T2  - Clinical Psychology in Europe
TI  - Effectiveness of Attachment-Based Family Therapy for Suicidal Adolescents and Young Adults: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001389345900005
UR  - https://cpe.psychopen.eu/index.php/cpe/article/download/13717/13717.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - BACKGROUND: Recent evidence indicates that the risk of death by suicide in teenagers has increased significantly worldwide. Consequently, different therapeutic interventions have been proposed for suicidal behavior in this particular population. Therefore, the main objective of this study is to provide an updated review of the existing psychological interventions for the treatment of suicide attempts (SA) in adolescents and to analyze the efficacy of such interventions. 

METHODS: A systematic review was conducted following PRISMA guidelines. The studies were identified by searching PubMed, PsychINFO, Web of Science, and Scopus databases from 2016 to 2022. According to the inclusion criteria, a total of 40 studies that tested the efficacy of different psychological interventions were selected.

RESULTS: Various psychological interventions for adolescents with suicidal behaviors were identified. Most of those present promising results. However, to summarize results from recent years, dialectical behavior therapy (DBT) was the most common and the only treatment shown to be effective for adolescents at high risk of suicide and SA. In contrast, empirical evidence for other psychological interventions focusing on deliberate self-harm (SH) is inconclusive. 

CONCLUSIONS: Interventions specifically designed to reduce suicidal risk in adolescents have multiplied significantly in recent years. There are a few promising interventions for reducing suicidal behaviors in adolescents evaluated by independent research groups. However, replication and dismantling studies are needed to identify the effects of these interventions and their specific components. An important future challenge is to develop brief and effective interventions to reduce the risk of death by suicide among the adolescent population.
AN  - 39414779
AU  - Garcia-Fernandez,
AU  - A.
AU  - Bobes-Bascaran,
AU  - T.
AU  - Martinez-Cao,
AU  - C.
AU  - Gonzalez-Blanco,
AU  - L.
AU  - Fernandez-Fernandez,
AU  - J.
AU  - Zurron-Madera,
AU  - P.
AU  - Seijo
AU  - Zazo,
AU  - E.
AU  - Jimenez-Trevino,
AU  - L.
AU  - Garcia-Portilla,
AU  - M.
AU  - P.
AU  - Bobes,
AU  - J.
AU  - Saiz,
AU  - P.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1038/s41398-024-03132-2
L1  - internal-pdf://0776401565/Garcia-Fernande-2024-Psychological interventio.pdf
PY  - 2024
SP  - 438
T2  - Transl Psychiatry Psychiatry
TI  - Psychological interventions for suicidal behavior in adolescents: a comprehensive systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1038%2fs41398-024-03132-2
UR  - https://www.nature.com/articles/s41398-024-03132-2.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Background
Anxiety and stress responses are often considered normative experiences, and children and adolescents may benefit from anxiety prevention programmes. One such programme is FRIENDS which is based on a firm theoretical model which addresses cognitive, physiological and behavioural processes. FRIENDS is manualised and can, thus, easily be integrated into school curriculums.

Objectives
What are the effects of the FRIENDS preventive programme on anxiety symptoms in children and adolescents? Do the effects differ between participant age groups, participant socio-economic status, type of prevention, type of provider, country of implementation and/or implementation issues in relation to the booster sessions and parent sessions?

Search Methods
The database searches were carried out in September 2023, and other sources were searched in October 2023. We searched to identify both published and unpublished literature. A date restriction from 1998 and onwards was applied.

Selection Criteria
The intervention was three age-appropriate preventive anxiety programmes: Fun FRIENDS, FRIENDS for Life, and My FRIENDS Youth. Primary outcome was anxiety symptoms and secondary outcome was self-esteem. Studies that used a control group were eligible, whereas qualitative approaches were not.

Data Collection and Analysis
The number of potentially relevant studies was 2865. Forty-two studies met the inclusion criteria. Twenty-eight studies were used in the data synthesis. Four studies had a critical risk of bias. Six studies did not report data that enabled calculation of effect sizes and standard errors. Two studies had partial overlap of data to other studies used, and two were written in Persian. Meta-analyses were conducted on each outcome separately. All analyses were inverse variance weighted using random effects statistical models.

Main Results
Studies came from 15 different countries. Intervention start varied from 2001 to 2016. The average number of participants analysed was 240, and the average number of controls was 212. Twenty-five comparisons reported on anxiety symptoms post-intervention. The weighted average standardised mean difference (SMD) was 0.13 (95% CI 0.04 to 0.22). There was some heterogeneity. Twelve comparisons reported on anxiety symptoms at 12 months follow-up. The weighted average SMD was 0.31 (95% CI 0.13 to 0.49). There was a large amount of heterogeneity. Five comparisons reported on self-esteem post-intervention with a weighted average SMD of 0.20 (95% CI &minus;0.20 to 0.61) and a large amount of heterogeneity. At follow-up, we found evidence that programmes implemented by mental health providers appears to perform better than programmes implemented by teachers. The evidence was inconclusive beyond 12 months follow-up.

Authors&#039; Conclusions
Our results indicate that the FRIENDS intervention may reduce anxiety symptoms in children and adolescents when reported by children and adolescents themselves. The majority of trials employed a wait-list design, implying only a few studies reported on the long-term effects of the FRIENDS intervention. Our findings suggest that the FRIENDS intervention may increase the reduction in anxiety symptoms 12 months after the intervention. This emphasises the need for future research that apply designs that allows for long-term follow-up. We are uncertain about the effects on self-esteem. The overall certainty of evidence varied from low to very low. There is a need for more rigorously conducted studies.
AU  - Filges,
AU  - T.
AU  - Smedslund,
AU  - G.
AU  - Eriksen,
AU  - T.
AU  - Birkefoss,
AU  - K.
AU  - Kildemoes,
AU  - M.
AU  - W.
DB  - November 2024.enl
DO  - /10.1002/cl2.1443
L1  - internal-pdf://4163656655/Campbell Systematic Reviews - 2024 - Filges -.pdf
PY  - 2024
SP  - e1443
T2  - Campbell Systematic Reviews
TI  - The FRIENDS preventive programme for reducing anxiety symptoms in children and adolescents: A systematic review and meta-analysis
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/cl2.1443
VL  - 20
ER  -
TY  - JOUR
AB  - BACKGROUND: Cannabinoids have been of increasing interest mainly due to their putative efficacy in a wide array of psychiatric, psychosomatic, and neurological conditions. 

AIMS: This systematic review aims to synthesize results from randomized placebo-controlled trials regarding the efficacy and the dosage of cannabinoids as therapeutics in psychiatric disorders in children, adolescents, and young adults. 

METHODS: All publications up to June 30th, 2024, were included from PubMed and Embase. Eligibility criteria in accordance with the PRISMA-guidelines was applied. RCTs providing pre- and post-treatment parameters on cannabinoid therapies for mental disorders in comparison to controls in an age range from 0 to 25 years were included. Effect sizes were calculated as Hedges&#039; g for primary outcomes, and a multilevel random-effects meta-analysis was conducted to account for dependent outcomes from same study populations. 

RESULTS: We identified 7603 records, of which 8 independent clinical trials (reported in 9 publications) met the pre-established eligibility criteria, comprising 474 unique participants (245 treatment, 229 control). Analysis of 13 primary outcomes (of 7 clinical trials) revealed a modest positive overall effect for symptom improvement or normalization of brain physiology (Hedges&#039; g = 0.308, 95% CI: 0.167, 0.448). Autism spectrum disorder studies showed the most consistent evidence (g = 0.264, 95% CI: 0.107, 0.421), while other conditions showed wider confidence intervals. Age-stratified analysis showed that adult populations (mean age 23.3 years, n = 5 outcomes) demonstrated higher effect sizes (g = 0.463, SD = 0.402) compared to pediatric populations (mean age 11.8 years, n = 8 outcomes; g = 0.318, SD = 0.212). Whole plant preparations (g = 0.328, 95% CI: 0.083, 0.573) and pharmaceutical cannabinoids (g = 0.292, 95% CI: 0.069, 0.515) showed comparable effects. CBD dosages ranged from 17.5 mg to 600 mg per day, with no significant correlation between dosage and effect size (rho = -0.014, p = 0.963). Mild to moderate side effects were reported, but no serious adverse events. Risk of bias assessment ranged from low (n = 3) to high (n = 5).

CONCLUSION: While meta-analysis of effect sizes for primary outcomes revealed modest positive effects, particularly for autism spectrum disorders, the current evidence remains insufficient to broadly recommend cannabinoids for treating mental disorders in youth populations. Larger, controlled studies with standardized outcomes are needed to establish definitive clinical recommendations.
AN  - 39696457
AU  - Kock,
AU  - P.
AU  - Badek,
AU  - A.
AU  - Meyer,
AU  - M.
AU  - Klaassen,
AU  - A.
AU  - L.
AU  - Walter,
AU  - M.
AU  - Kindler,
AU  - J.
DB  - Desember 2024.enl
DO  - /10.1186/s13034-024-00846-5
L1  - internal-pdf://0830733506/Kock-2024-Cannabinoids for treating psychiatri.pdf
PY  - 2024
SP  - 158
T2  - Child &amp; Adolescent Psychiatry &amp; Mental Health [Electronic Resource]
TI  - Cannabinoids for treating psychiatric disorders in youth: a systematic review of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.1186%2fs13034-024-00846-5
UR  - https://capmh.biomedcentral.com/counter/pdf/10.1186/s13034-024-00846-5.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - Humanitarian emergencies pose a significant global health challenge for children and young people&#039;s mental and psychological health. This systematic review investigates the effectiveness of mental health and psychosocial support (MHPSS) programmes delivered to children and young people affected by humanitarian emergencies in low- and middle-income countries (LMICs). Twelve electronic databases, key websites and citation checking were undertaken. Forty-three randomised controlled trials (RCTs) published in English between January 1980 and May 2023 were included in the review. Overall, the findings suggest that cognitive behavioural therapy may improve depression symptoms in children and young people affected by humanitarian emergencies. Narrative exposure therapy may reduce feelings of guilt. However, the impact of the other MHPSS modalities across outcomes is inconsistent. In some contexts, providing psychosocial programmes involving creative activities may increase the symptoms of depression in children and young people. These findings emphasise the need for the development of MHPSS programmes that can safely and effectively address the diverse needs of children and young people living in adversarial environments.
AN  - WOS:001193242700001
AU  - Bangpan,
AU  - M.
AU  - Felix,
AU  - L.
AU  - Soliman,
AU  - F.
AU  - D&#039;Souza,
AU  - P.
AU  - Jieman,
AU  - A.
AU  - T.
AU  - Dickson,
AU  - K.
DB  - April 24.enl
DO  - 10.1017/gmh.2024.17
L1  - internal-pdf://1433840122/Bangpan-2024-The impact of mental health and p.pdf
PY  - 2024
SP  - 16
T2  - Cambridge Prisms-Global Mental Health
TI  - The impact of mental health and psychosocial support programmes on children and young people&#039;s mental health in the context of humanitarian emergencies in low- and middle-income countries: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001193242700001
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/9EFA1694EF877E1A4F760754AD511B9B/S2054425124000177a.pdf/div-class-title-the-impact-of-mental-health-and-psychosocial-support-programmes-on-children-and-young-people-s-mental-health-in-the-context-of-humanitarian-emergencies-in-low-and-middle-income-countries-a-systematic-review-and-meta-analysis-div.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - BACKGROUND: Virtual Reality (VR) based diagnostic and therapeutic interventions have opened up new possibilities for addressing the challenges in identifying and treating individuals with Autism Spectrum Disorders (ASD). 

AIM: To conduct a systematic review and meta-analysis of Randomized Controlled Trials to investigate the impact of Immersive VR techniques on the cognitive, social, and emotional skills of under-18 children and adolescents with ASD. 

METHODS AND PROCEDURES: Four databases were systematically searched as per &quot;Preferred Reporting Items for Systematic Reviews and Meta-analyses&quot; guidelines and assessed six RCTs for further analysis. The Cochrane Risk of Bias tool was used to assess the methodological quality of the studies. 

OUTCOMES: Pooled results favoured VR and reported significant differences between experimental and control groups concerning social skills (SMD:1.43; 95 % CI: 0.01-2.84; P: 0.05), emotional skills (SMD: 2.45; 95 % CI: 0.21-4.18; P: 0.03) and cognitive skills. 

CONCLUSION: VR offers an array of benefits that make it a promising tool for children and adolescents with ASD to improve their cognitive, social and emotional skills in a safe and supportive setting. However, accessibility, affordability, customization, and cost are also significant aspects to consider when developing and implementing VR-based interventions for ASD.
AN  - 38941690
AU  - Mittal,
AU  - P.
AU  - Bhadania,
AU  - M.
AU  - Tondak,
AU  - N.
AU  - Ajmera,
AU  - P.
AU  - Yadav,
AU  - S.
AU  - Kukreti,
AU  - A.
AU  - Kalra,
AU  - S.
AU  - Ajmera,
AU  - P.
DB  - Juli 2024.enl
DO  - /10.1016/j.ridd.2024.104771
L1  - internal-pdf://1354250581/1-s2.0-S0891422224001033-main.cleaned.pdf
PY  - 2024
SP  - 104771
T2  - Research in Developmental Disabilities
TI  - Effect of immersive virtual reality-based training on cognitive, social, and emotional skills in children and adolescents with autism spectrum disorder: A meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1016%2fj.ridd.2024.104771
VL  - 151
ER  -
TY  - JOUR
AB  - BACKGROUND: Cognitively combined/engaged physical activity (CC/CE-PA) has been used as an intervention for children/adolescents with attention-deficit/hyperactivity disorder (ADHD). 

METHOD: This review aimed to quantify the effects of CC/CE-PAs on enhancing executive and physical function and alleviating ADHD symptoms in children/adolescents with ADHD. An extensive literature search of online databases identified 32 studies (75% high-quality studies), of which 22 (pooled n=968) were included in the meta-analysis.

RESULTS: The included studies covered five PA types with varying intervention periods, frequencies, and exercise durations. The CC/CE-PAs showed an overall significant effect on improving executive function (standardized mean difference [SMD]: 1.10) and motor competence (SMD: 0.52) and alleviating ADHD symptoms (SMD: -0.75). Program design and participants&#039; medication status were found to significantly moderate the effect of CC/CE-PA.

CONCLUSION: More evidence is needed to support the effect of CC/CE-PA by comparing it with other interventions and using a rigorous experimental design.
AN  - 39550802
AU  - Fang,
AU  - Y.
AU  - Sun,
AU  - F.
AU  - Wang,
AU  - Z.
AU  - Yang,
AU  - Y.
AU  - Lau,
AU  - M.
AU  - Huang,
AU  - K.
AU  - Yeung,
AU  - M.
AU  - K.
AU  - Kranz,
AU  - G.
AU  - S.
AU  - Chan,
AU  - C.
AU  - C.
AU  - H.
DB  - November 2024.enl
DO  - /10.1016/j.ridd.2024.104880
L1  - internal-pdf://3191572338/1-s2.0-S0891422224002129-main.pdf
PY  - 2024
SP  - 104880
T2  - Research in Developmental Disabilities
TI  - Cognitively combined/engaged physical activity for the executive function, symptomology, and motor competence of children and adolescents with attention-deficit/hyperactivity disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.ridd.2024.104880
UR  - https://www.sciencedirect.com/science/article/pii/S0891422224002129?via%3Dihub
VL  - 155
ER  -
TY  - JOUR
AB  - Importance: Anxiety, depression, and attention-deficit/hyperactivity disorder (ADHD) affect up to 20% of children and adolescents. Despite demonstrated efficacy, evidence-based treatments for these conditions are often inaccessible; innovative solutions are essential to meet the demand for pediatric mental health care. 

Objective: To examine the efficacy and moderators of gamified DMHIs for anxiety, depression, and ADHD in randomized clinical trials (RCTs) for children and adolescents. 

Data Sources: A systematic search of PubMed, PsycInfo, and Web of Science was conducted for RCTs published before March 20, 2024. 

Study Selection: RCTs that evaluated the efficacy of gamified DMHIs for treating pediatric ADHD, depression, or anxiety were included. Studies were excluded if they did not use a gamified DMHI, provide sufficient data for effect sizes, or were unavailable in English. 

Data Extraction and Synthesis: Efficacy data were extracted from rating scales for ADHD, depression, and anxiety. Extracted moderator variables included participant characteristics (eg, age and sex), intervention characteristics (eg, delivery modality and time limit), and trial design characteristics (eg, outcome measure and risk of bias). 

Main Outcomes and Measures: The primary outcome was change in ADHD, depression, or anxiety severity in the treatment group compared to the control group. Hedges g quantified treatment effects. <b>Results</b>: The search strategy identified 27 RCTs that included 2911 participants across ADHD, depression, and anxiety disorders. There were modest significant effects of gamified DMHIs on ADHD (g, 0.28; 95% CI, 0.09 to 0.48) and depression (g, 0.28; 95% CI, 0.08 to 0.47) but small, nonsignificant effects for anxiety disorders (g, 0.07; 95% CI, -0.02 to 0.17). Moderator analyses revealed that DMHIs for ADHD delivered on a computer and those RCTs that had a greater preponderance of male participants produced larger treatment effects. DMHIs for depressive disorders that used preset time limits for gamified DMHIs also exhibited larger treatment effects.

Conclusions and Relevance: The findings suggest a benefit of gamified DMHIs for youth with ADHD or depressive disorder. Pediatricians and other health care professionals have new information about novel, accessible, and efficacious options for pediatric mental health care.
AN  - 39312259
AU  - Bryant,
AU  - B.
AU  - R.
AU  - Sisk,
AU  - M.
AU  - R.
AU  - McGuire,
AU  - J.
AU  - F.
DB  - September 2024.enl
DO  - /10.1001/jamapediatrics.2024.3139
L1  - internal-pdf://2230736416/jamapediatrics_bryant_2024_oi_240057_172616945.pdf
PY  - 2024
SP  - 23
T2  - Jama Pediatrics
TI  - Efficacy of Gamified Digital Mental Health Interventions for Pediatric Mental Health Conditions: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1001%2fjamapediatrics.2024.3139
UR  - https://jamanetwork.com/journals/jamapediatrics/article-abstract/2823863
VL  - 23
ER  -
TY  - JOUR
AB  - (1) Background: Previous studies have identified discrepancies in improvements in executive functioning in typically developing children when comparing closed- and open-skill exercise interventions. However, there is limited research on executive functioning in attention deficit hyperactivity disorder (ADHD). This study aims to conduct a systematic review and meta-analysis to explore the impact of closed- and open-skill exercises on ADHD populations. 

(2) Methods: The PRISMA guidelines for systematic reviews were followed to search seven databases to evaluate and analyze studies published from 2013 to 2023. Prospero: CRD42023460452. 

(3) Results: A meta-analysis of 578 subjects with ADHD in 11 RCTs (Randomized control trial) and 3 NRS (Non-randomized studies) revealed that closed-skill exercise significantly improved executive function subdomains, including inhibitory control (standardized mean differences (SMD) = -1.00), cognitive flexibility (SMD = -1.33), and working memory (SMD = -0.85). Furthermore, open-skill exercise was found to have a positive effect on inhibitory control (SMD = -1.98) and cognitive flexibility (SMD = -0.97) in ADHD patients. Both types of exercise interventions demonstrated an improvement in executive function compared to controls, with open-skill exercises exhibiting superior effects (Q&lt;sub&gt;b&lt;/sub&gt; = 6.26). 

(4) Conclusions: The review recommends a 12-week intervention cycle with exercise at least twice a week of moderate or higher intensity as suitable for ADHD individuals. This review also encourages individuals with ADHD to engage in exercises involving multiple motor skill types.
AN  - 38920831
AU  - Qiu,
AU  - C.
AU  - Zhai,
AU  - Q.
AU  - Chen,
AU  - S.
DB  - Juni 24.enl
DO  - /10.3390/bs14060499
L1  - internal-pdf://3672730530/Qiu-2024-Effects of Practicing Closed- vs. Ope.pdf
PY  - 2024
SP  - 14
T2  - Behavioral sciences
TI  - Effects of Practicing Closed- vs. Open-Skill Exercises on Executive Functions in Individuals with Attention Deficit Hyperactivity Disorder (ADHD)-A Meta-Analysis and Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3390%2fbs14060499
UR  - https://mdpi-res.com/d_attachment/behavsci/behavsci-14-00499/article_deploy/behavsci-14-00499.pdf?version=1718347337
VL  - 14
ER  -
TY  - JOUR
AB  - **Background**
Obesity is considered to be a risk factor for various diseases, and its incidence has tripled worldwide since 1975. In addition to potentially being at risk for adverse health outcomes, people with overweight or obesity are often stigmatised. Behaviour change interventions are increasingly delivered as mobile health (m‐health) interventions, using smartphone apps and wearables. They are believed to support healthy behaviours at the individual level in a low‐threshold manner.

**Objectives**
To assess the effects of integrated smartphone applications for adolescents and adults with overweight or obesity.

**Search methods**
We searched CENTRAL, MEDLINE, PsycINFO, CINAHL, and LILACS, as well as the trials registers ClinicalTrials.gov and World Health Organization International Clinical Trials Registry Platform on 2 October 2023 (date of last search for all databases). We placed no restrictions on the language of publication.

**Selection criteria**
Participants were adolescents and adults with overweight or obesity. Eligible interventions were integrated smartphone apps using at least two behaviour change techniques. The intervention could target physical activity, cardiorespiratory fitness, weight loss, healthy diet, or self‐efficacy. Comparators included no or minimal intervention (NMI), a different smartphone app, personal coaching, or usual care. Eligible studies were randomised controlled trials of any duration with a follow‐up of at least three months.

**Data collection and analysis**
We used standard Cochrane methodology and the RoB 2 tool. Important outcomes were physical activity, body mass index (BMI) and weight, health‐related quality of life, self‐efficacy, well‐being, change in dietary behaviour, and adverse events. We focused on presenting studies with medium‐ (6 to &lt; 12 months) and long‐term (&ge; 12 months) outcomes in our summary of findings table, following recommendations in the core outcome set for behavioural weight management interventions.

**Main results**
We included 18 studies with 2703 participants. Interventions lasted from 2 to 24 months. The mean BMI in adults ranged from 27 to 50, and the median BMI z‐score in adolescents ranged from 2.2 to 2.5.

Smartphone app versus no or minimal intervention

Thirteen studies compared a smartphone app versus NMI in adults; no studies were available for adolescents. The comparator comprised minimal health advice, handouts, food diaries, smartphone apps unrelated to weight loss, and waiting list.

Measures of physical activity: at 12 months&#039; follow‐up, a smartphone app compared to NMI probably reduces moderate to vigorous physical activity (MVPA) slightly (mean difference (MD) &minus;28.9 min/week (95% confidence interval (CI) &minus;85.9 to 28; 1 study, 650 participants; moderate‐certainty evidence)). We are very uncertain about the results of estimated energy expenditure and cardiorespiratory fitness at eight months&#039; follow‐up. A smartphone app compared with NMI probably results in little to no difference in changes in total activity time at 12 months&#039; follow‐up and leisure time physical activity at 24 months&#039; follow‐up.

Anthropometric measures: a smartphone app compared with NMI may reduce BMI (MD of BMI change &minus;2.6 kg/m2, 95% CI &minus;6 to 0.8; 2 studies, 146 participants; very low‐certainty evidence) at six to eight months&#039; follow‐up, but the evidence is very uncertain. At 12 months&#039; follow‐up, a smartphone app probably resulted in little to no difference in BMI change (MD &minus;0.1 kg/m2, 95% CI &minus;0.4 to 0.3; 1 study; 650 participants; moderate‐certainty evidence). A smartphone app compared with NMI may result in little to no difference in body weight change (MD &minus;2.5 kg, 95% CI &minus;6.8 to 1.7; 3 studies, 1044 participants; low‐certainty evidence) at 12 months&#039; follow‐up. At 24 months&#039; follow‐up, a smartphone app probably resulted in little to no difference in body weight change (MD 0.7 kg, 95% CI &minus;1.2 to 2.6; 1 study, 245 participants; moderate‐certainty evidence).

A smartphone app compared with NMI may result in little to no difference in self‐efficacy for a physical activity score at eight months&#039; follow‐up, but the results are very uncertain. A smartphone app probably results in little to no difference in quality of life and well‐being at 12 months (moderate‐certainty evidence) and in little to no difference in various measures used to inform dietary behaviour at 12 and 24 months&#039; follow‐up.

We are very uncertain about adverse events, which were only reported narratively in two studies (very low‐certainty evidence).

Smartphone app versus another smartphone app

Two studies compared different versions of the same app in adults, showing no or minimal differences in outcomes. One study in adults compared two different apps (calorie counting versus ketogenic diet) and suggested a slight reduction in body weight at six months in favour of the ketogenic diet app. No studies were available for adolescents.

Smartphone app versus personal coaching

Only one study compared a smartphone app with personal coaching in adults, presenting data at three months. Two studies compared these interventions in adolescents. A smartphone app resulted in little to no difference in BMI z‐score compared to personal coaching at six months&#039; follow‐up (MD 0, 95% CI &minus;0.2 to 0.2; 1 study; 107 participants).

Smartphone app versus usual care

Only one study compared an app with usual care in adults but only reported data at three months on participant satisfaction. No studies were available for adolescents.

We identified 34 ongoing studies.

**Authors&#039; conclusions**
The available evidence is limited and does not demonstrate a clear benefit of smartphone applications as interventions for adolescents or adults with overweight or obesity. While the number of studies is growing, the evidence remains incomplete due to the high variability of the apps&#039; features, content and components, which complicates direct comparisons and assessment of their effectiveness. Comparisons with either no or minimal intervention or personal coaching show minor effects, which are mostly not clinically significant. Minimal data for adolescents also warrants further research. Evidence is also scarce for low‐ and middle‐income countries as well as for people with different socio‐economic and cultural backgrounds. The 34 ongoing studies suggest sustained interest in the topic, with new evidence expected to emerge within the next two years. In practice, clinicians and healthcare practitioners should carefully consider the potential benefits, limitations, and evolving research when recommending smartphone apps to adolescents and adults with overweight or obesity.
AN  - CD013591
AU  - Metzendorf,
AU  - M.
AU  - I.
AU  - Wieland,
AU  - L.
AU  - S.
AU  - Richter,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/14651858.CD013591.pub2
KW  - *Overweight [therapy]
KW  - *Telemedicine
KW  - Adolescent
KW  - Adult
KW  - Humans
KW  - Obesity [therapy]
KW  - Quality of Life
KW  - Smartphone
KW  - Weight Loss
L1  - internal-pdf://0641611254/Metzendorf_et_al-2024-Cochrane_Database_of_Sys.pdf
N1  - [Metabolic and Endocrine Disorders]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Mobile health (m‐health) smartphone interventions for adolescents and adults with overweight or obesity
UR  - http://dx.doi.org/10.1002/14651858.CD013591.pub2
ER  -
TY  - JOUR
AB  - Objectives: This systematic review sought to provide evidence for the effectiveness of common pharmacological interventions used for treating attention deficit hyperactivity disorder (ADHD) symptoms in the autism spectrum disorder (ASD) population, considering studies attempting to find safe and effective drugs. 

Methods: We searched for randomized controlled trials describing the effectiveness and/or safety profile of pharmacological interventions for treating ASD and ADHD or ASD with ADHD symptoms using three bibliographic databases: PubMed, Cochrane Library, and Embase. We have chosen ADHD symptoms measured by any clinical scale as the primary outcome. As additional outcomes, we have used other symptoms of aberrant behavior measured by the aberrant behavior checklist, satisfaction with treatment, and peer satisfaction. 

Results: Twenty-two publications met the inclusion criteria for the systematic review and eight for the metaanalysis. In our investigation, we found a few articles using clonidine, modafinil, and bupropion as interventions when compared to methylphenidate (MPH). Our meta-analysis showed that MPH had positive changes compared to placebo in symptoms such as hyperactivity, irritability, or inattention. However, no effect was found in stereotyped symptoms, and our data &#039;s quantitative analysis revealed a large effect of MPH-induced adverse effects on the dropout rate. On the other hand, atomoxetine initiation had positive effects when compared to placebo on symptoms of hyperactivity and inattention. We have found no effect of atomoxetine on stereotypes or irritability. Furthermore, atomoxetine did not influence side effects that caused dropouts from studies. 

Conclusion: Our results indicated that atomoxetine has a modest effect on hyperactivity and inattention symptoms, with a relatively benign profile of side effects. MPH appears to be effective in handling hyperactivity, inattention, and irritability symptoms. However, our results on atomoxetine revealed increased dropouts due to adverse effects when compared to MPH or placebo. Evidence for other substances such as guanfacine, clonidine, bupropion, or modafinil is either preliminary or nonexistent.
AN  - WOS:001273516600001
AU  - Martins,
AU  - P.
AU  - L.
AU  - B.
AU  - Torquato,
AU  - G.
AU  - C.
AU  - P.
AU  - Dias,
AU  - Gapf
AU  - Leite,
AU  - I.
AU  - B.
AU  - Gaspar,
AU  - T.
AU  - M.
AU  - Pinto,
AU  - J.
AU  - P.
AU  - Macedo,
AU  - D.
AU  - S.
DB  - August 2024.enl
DO  - 10.1016/j.pnpbp.2024.111089
L1  - internal-pdf://1681416085/1-s2.0-S027858462400157X-main.pdf
PY  - 2024
SP  - 16
T2  - Progress in Neuro-Psychopharmacology &amp; Biological Psychiatry
TI  - Effectiveness of pharmacological interventions for managing ADHD symptoms in individuals with autism spectrum disorder: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001273516600001
VL  - 134
ER  -
TY  - JOUR
AB  - Psychological interventions can help reduce posttraumatic stress symptoms (PTSS) in youth, but many do not seek help. Internet- and mobile-based interventions (IMIs) show promise in expanding treatment options. However, the overall evidence on IMIs in reducing PTSS among youth remains unclear. This systematic review and meta-analysis investigated the efficacy of IMIs in PTSS reduction for youth exposed to traumatic events. A comprehensive literature search was conducted in January 2023 including non-randomized and randomized-controlled trials (RCT) investigating the effects of IMIs on PTSS in youth aged &lt;=25 years. Six studies were identified with five providing data for the meta-analysis. The majority of studies included youth with different types of trauma irrespective of PTSS severity at baseline (k = 5). We found a small within-group effect in reducing PTSS from baseline to post-treatment (g = -0.39, 95% CrI: -0.67 to -0.11, k = 5; n = 558; 9 comparisons). No effect emerged when comparing the effect of IMIs to control conditions (g = 0.04; 95%-CrI: -0.52 to 0.6, k = 3; n = 768; k = 3; 4 comparisons). Heterogeneity was low between and within studies. All studies showed at least some concerns in terms of risk of bias. Current evidence does not conclusively support the overall efficacy of IMIs in addressing youth PTSS. This review revealed a scarcity of studies investigating IMIs for youth exposed to traumatic events, with most being feasibility studies rather than adequately powered RCTs and lacking a trauma focus. This underscores the demand for more high-quality research.
AN  - 38424186
AU  - Schulte,
AU  - C.
AU  - Harrer,
AU  - M.
AU  - Sachser,
AU  - C.
AU  - Weiss,
AU  - J.
AU  - Zarski,
AU  - A.
AU  - C.
DB  - Mars 24.enl
DO  - /10.1038/s41746-024-01042-7
L1  - internal-pdf://2711471411/Schulte-2024-Internet- and mobile-based psycho.pdf
PY  - 2024
SP  - 50
T2  - Npj Digital Medicine
TI  - Internet- and mobile-based psychological interventions for post-traumatic stress symptoms in youth: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.1038%2fs41746-024-01042-7
UR  - https://www.nature.com/articles/s41746-024-01042-7.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - **Background**
This study addresses the pervasive issue of heightened preoperative anxiety in healthcare, particularly among pediatric patients. Recognizing the various sources of anxiety, we explored both pharmacological and nonpharmacological interventions. Focusing on distraction techniques, including active and passive forms, our meta-analysis aimed to provide comprehensive insights into their impact on preoperative anxiety in pediatric patients. 

**Methods**
Following the PRISMA and Cochrane guidelines, this meta-analysis and systematic review assessed the efficacy of pharmaceutical and distraction interventions in reducing pain and anxiety in pediatric surgery. This study was registered on PROSPERO (CRD42023449979). 

**Results**
 This meta-analysis, comprising 45 studies, investigated pharmaceutical interventions and distraction tactics in pediatric surgery. Risk of bias assessment revealed undisclosed risks in performance and detection bias. Distraction interventions significantly reduced preoperative anxiety compared to control groups, with notable heterogeneity. Comparison with Midazolam favored distraction techniques. Subgroup analysis highlighted varied efficacies among distraction methods, with a notable reduction in anxiety levels. Sensitivity analysis indicated stable results. However, publication bias was observed, suggesting a potential reporting bias. 

**Conclusion** 
Our study confirms distraction techniques as safe and effective for reducing pediatric preoperative anxiety, offering a valuable alternative to pharmacological interventions. 

Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=449979, PROSPERO [CRD42023449979].
AN  - 38440185
AU  - Mustafa,
AU  - M.
AU  - S.
AU  - Shafique,
AU  - M.
AU  - A.
AU  - Zaidi,
AU  - Sdez
AU  - Qamber,
AU  - A.
AU  - Rangwala,
AU  - B.
AU  - S.
AU  - Ahmed,
AU  - A.
AU  - Zaidi,
AU  - S.
AU  - M.
AU  - F.
AU  - Rangwala,
AU  - H.
AU  - S.
AU  - Uddin,
AU  - M.
AU  - M.
AU  - N.
AU  - Ali,
AU  - M.
AU  - Siddiq,
AU  - M.
AU  - A.
AU  - Haseeb,
AU  - A.
DB  - Mars 24.enl
DO  - /10.3389/fped.2024.1353508
L1  - internal-pdf://2135279165/Mustafa-2024-Preoperative anxiety management i.pdf
PY  - 2024
SP  - 1353508
T2  - Frontiers in Pediatrics
TI  - Preoperative anxiety management in pediatric patients: a systemic review and meta-analysis of randomized controlled trials on the efficacy of distraction techniques
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffped.2024.1353508
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10909818/pdf/fped-12-1353508.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) is highly prevalent in early childhood and has long-term negative effects when left untreated. Parent-Child Interaction Therapy (PCIT) is an early intervention for children aged 2- to-7-years that has extensive evidence for treating child externalizing problems by teaching parents effective strategies to manage child behavior. However, the effect of PCIT for families with children diagnosed with ADHD is not completely understood. This meta-analysis aims to synthesize research on the use of PCIT for children with ADHD. Nine out of 711 identified studies were analyzed. Summary effect sizes were calculated using the standardized mean gain for child ADHD symptoms, child behaviors, parent stress, and parenting behaviors, and the Fail-Safe N was calculated to determine the robustness of the results. Overall, PCIT had a significant beneficial effect on child ADHD symptoms (g = 0.90), child behavior (g = 0.44), parent stress (g = 0.82), and parenting behaviors (g = 2.15). Results of this meta-analysis suggest that PCIT is an effective treatment for reducing core symptoms of ADHD.
AN  - 38441815
AU  - Phillips,
AU  - S.
AU  - T.
AU  - Druskin,
AU  - L.
AU  - R.
AU  - Mychailyszyn,
AU  - M.
AU  - P.
AU  - Victory,
AU  - E.
AU  - Aman,
AU  - E.
AU  - McNeil,
AU  - C.
AU  - B.
DB  - Mars 24.enl
DO  - /10.1007/s10578-024-01678-2
L1  - internal-pdf://0386123137/Phillips-2024-The Efficacy of Parent-Child Int.pdf
PY  - 2024
SP  - 05
T2  - Child Psychiatry &amp; Human Development
TI  - The Efficacy of Parent-Child Interaction Therapy (PCIT) for Youth with Attention-Deficit/Hyperactivity Disorder (ADHD): A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs10578-024-01678-2
UR  - https://link.springer.com/article/10.1007/s10578-024-01678-2
UR  - https://link.springer.com/content/pdf/10.1007/s10578-024-01678-2.pdf
VL  - 05
ER  -
TY  - JOUR
AB  - **Background:** 
Clinical trials of new drugs for tic disorders (TD) often fail to yield positive results. Placebo and nocebo responses play a vital role in interpreting the outcomes of randomized controlled trials (RCTs), yet these responses in RCTs of TD remain unexplored. 

**Objective:** 
The aim was to assess the magnitude of placebo and nocebo responses in RCTs of pharmacological interventions for TD and identify influencing factors. 

**Methods:** 
A systematic search of the Embase, Medline, Cochrane Central Register of Controlled Trials, and PsycINFO databases was conducted. Eligible studies were RCTs that compared active pharmacological agents with placebos. Placebo response was defined as the change from baseline in TD symptom severity in the placebo group, and nocebo response as the proportion experiencing adverse events (AEs) in this group. Subgroup analysis and meta-regression were performed to explore modifying factors.

**Results:** 
Twenty-four trials involving 2222 participants were included in this study. A substantial placebo
response in TD symptom severity was identified, with a pooled effect size of 0.79 (95% confidence interval [CI] 0.99 to 0.59; I2 = 67%). Forty-four percent (95% CI 27% to 63%; I2 = 92%) of patients experienced AEs while taking inert pills. Sample size, study design, and randomization ratio were correlated with changes in placebo and nocebo responses. 

**Conclusion:** 
There were considerable placebo and nocebo responses in TD clinical trials. These results are of great relevance for the design of future trials and for clinical practice in TD. Systematic review registration: PROSPERO registration ID CRD42023388397. &copy; 2024 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
AN  - WOS:001153249900001
AU  - Wang,
AU  - S.
AU  - M.
AU  - Xiong,
AU  - Z.
AU  - Y.
AU  - Cui,
AU  - Y.
AU  - H.
AU  - Fan,
AU  - F.
AU  - Zhang,
AU  - S.
AU  - Jia,
AU  - R.
AU  - Hu,
AU  - Y.
AU  - C.
AU  - Li,
AU  - L.
AU  - Zhang,
AU  - X.
AU  - Han,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/mds.29714
L1  - internal-pdf://0398746182/Movement Disorders - 2024 - Wang - Placebo and.pdf
PY  - 2024
SP  - 12
T2  - Movement Disorders
TI  - Placebo and Nocebo Responses in Pharmacological Trials of Tic Disorders: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001153249900001
ER  -
TY  - JOUR
AB  - The increasing prevalence of cyberbullying victimization has become a commonplace issue globally. Although research has explored various predictors and consequences of cyberbullying victimization, most focus on a narrow range of variables or contexts, highlighting the need to comprehensively review and synthesize the wealth of empirical findings. We conducted a systematic review of meta-analyses on cyberbullying victimization, incorporating 56 meta-analyses and 296 effect sizes (sample size range 421-1,136,080, sample size median 53,183; searched via EBSCOhost ERIC, EBSCOhost PsycInfo, PubMed, Scopus, Web of Science, 13 cyberbullying-related journals, Google Scholar and ProQuest Dissertations and Theses) to address the following critical questions: (1) What are the crucial sociodemographic and psychological profiles of cyberbullying victims? (2) What critical contextual and environmental factors are associated with cyberbullying victimization? (3) What are the key psychological and behavioural consequences of cyberbullying victimization? (4) How effective are existing interventions in mitigating impacts of cyberbullying? Included meta-analyses had to focus on cyberbullying victimization and report at least one predictor or consequence. A quality assessment was conducted using the Joanna Briggs Institute Critical Appraisal Instrument for Systematic Reviews and Research Syntheses. Findings suggest that females, school-aged populations, traditional bullying victims and frequent internet users were more likely to be cyberbullied. Unregulated school environments and unsupportive parental relationships were also associated with increased cyberbullying victimization. Cyberbullying victimization was consistently associated with negative psychological outcomes, lower school performance and maladaptive coping behaviours. More importantly, the current review found that cyberbullying intervention programmes show promising results. The current review underscores the importance of devoting adequate resources to mitigating cyberbullying victimization. This umbrella review of 56 meta-analyses and 296 effect sizes examines the risk factors, protective factors and consequences of cyberbullying. The authors also examine interventions to mitigate cyberbullying victimization.
AN  - WOS:001350163700001
AU  - Kasturiratna,
AU  - Ktas
AU  - Hartanto,
AU  - A.
AU  - Chen,
AU  - C.
AU  - H.
AU  - Y.
AU  - Tong,
AU  - E.
AU  - M.
AU  - W.
AU  - Majeed,
AU  - N.
AU  - M.
DB  - November 2024.enl
DO  - 10.1038/s41562-024-02011-6
L1  - internal-pdf://4000873262/Kasturiratna-2024-Umbrella review of meta-anal.pdf
PY  - 2024
SP  - 35
T2  - Nature Human Behaviour
TI  - Umbrella review of meta-analyses on the risk factors, protective factors, consequences and interventions of cyberbullying victimization
UR  - &lt;Go to ISI&gt;://WOS:001350163700001
UR  - https://www.nature.com/articles/s41562-024-02011-6.pdf
ER  -
TY  - JOUR
AB  - Background 
Antipsychotics and mood stabilisers are gathering attention for the disturbance of metabolism. This network meta -analysis aims to evaluate and rank the metabolic effects of the commonly used antipsychotics and mood stabilisers in treating bipolar disorder (BD). 

Methods 
Registries including PubMed, Embase, Cochrane Library, Web of Science, Ovid, and Google Scholar were searched before February 15th, 2024, for randomised controlled trials (RCTs) applying antipsychotics or mood stabilisers for BD treatment. The observed outcomes were twelve metabolic indicators. The data were extracted by two reviewers independently, and con fi rmed by another four reviewers and a corresponding author. The above six reviewers all participated in data analyses. Data extraction was based on PRISMA guidelines, and quality assessment was conducted according to the Cochrane Handbook . Use a random effects model for data pooling. The PROSPERO registration number is CRD42023466669. 

Findings 
Together, 5421 records were identi fi ed, and 41 publications with 11,678 complete -trial participants were con fi rmed eligible. After eliminating possible sensitivity, risperidone ranked 1st in elevating fasting serum glucose (SUCRA = 90.7%) and serum insulin (SUCRA = 96.6%). Lurasidone was most likely to elevate HbA1c (SUCRA = 82.1%). Olanzapine ranked 1st in elevating serum TC (SUCRA = 93.3%), TG (SUCRA = 89.6%), and LDL (SUCRA = 94.7%). Lamotrigine ranked 1st in reducing HDL (SUCRA = 82.6%). Amisulpride ranked 1st in elevating body weight (SUCRA = 100.0%). For subgroup analyses, quetiapine is more likely to affect indicators of glucose metabolism among male adult patients with bipolar mania, while long-term lurasidone tended to affect glucose metabolism among female patients with bipolar depression. Among patients under 18, divalproex tended to affect glucose metabolism, with lithium affecting lipid metabolism. In addition, most observed antipsychotics performed higher response and remission rates than placebo, and displayed a similar dropout rate with placebo, while no between -group signi fi cance of rate was observed among mood stabilisers. Interpretation Our findings suggest that overall, antipsychotics are effective in treating BD, while they are also more likely to disturb metabolism than mood stabilisers. Attention should be paid to individual applicability in clinical practice. The results put forward evidence -based information and clinical inspiration for drug compatibility and further research of the BD mechanism. 

Copyright (c) 2024 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY -NC -ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
AN  - WOS:001226690400001
AU  - Kong,
AU  - L.
AU  - Z.
AU  - Wang,
AU  - H.
AU  - Z.
AU  - Yan,
AU  - N.
AU  - Xu,
AU  - C.
AU  - Y.
AU  - Chen,
AU  - Y.
AU  - Q.
AU  - Zeng,
AU  - Y.
AU  - Y.
AU  - Guo,
AU  - X.
AU  - A.
AU  - Lu,
AU  - J.
AU  - Hu,
AU  - S.
AU  - H.
DB  - Juni 24.enl
DO  - 10.1016/j.eclinm.2024.102581
L1  - internal-pdf://2721672645/1-s2.0-S2589537024001603-main.cleaned.pdf
N1  - Brynhildur Axelsdottir (2024-07-04 18:15:02)(Select): Er noen resultater for ungdom, subgruppe-analyser. ;
PY  - 2024
SP  - 15
T2  - Eclinicalmedicine
TI  - Effect of antipsychotics and mood stabilisers on metabolism in bipolar disorder: a network meta-analysis of randomised-controlled trials
UR  - &lt;Go to ISI&gt;://WOS:001226690400001
VL  - 71
ER  -
TY  - JOUR
AB  - Mental health conditions constitute a major burden of disease for adolescents globally and can lead to significant adverse consequences. This systematic review aimed to identify if psychosocial interventions are effective in preventing mental health conditions in adolescents already experiencing emotional problems. We searched for randomized controlled trials comparing psychosocial interventions for preventing mental health conditions with care as usual in adolescents aged 10-19 who are experiencing symptoms of emotional problems. We searched PubMed/Medline, PsycINFO, ERIC, EMBASE, and ASSIA databases to identify studies. We found 82 eligible studies (n = 13,562 participants). Findings show that interventions can reduce mental health conditions and increase positive mental health. Across all reported time points, psychosocial interventions showed significant, small-to moderate-sized beneficial effects on preventing mental health conditions (SMD: -0.26, 95% CI [-0.42, -0.19] and small positive effects on positive mental health (SMD: 0.17, 95% CI [0.097, 0.29]. There were no statistically significant pooled findings suggesting that psychosocial interventions had either a positive or negative effect on self-harm or suicide; aggressive, disruptive and oppositional behavior; substance use; or school attendance. Despite the positive findings, a critical gap exists in the design of effective psychosocial interventions to reduce self-harm and suicide, and other risk behaviors in adolescents with symptoms of emotional problems.
AN  - 39556075
AU  - Du
AU  - Toit,
AU  - S.
AU  - Tomlinson,
AU  - M.
AU  - Laurenzi,
AU  - C.
AU  - A.
AU  - Gordon,
AU  - S.
AU  - Hartmann,
AU  - L.
AU  - Abrahams,
AU  - N.
AU  - Bradshaw,
AU  - M.
AU  - Brand,
AU  - A.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Servili,
AU  - C.
AU  - Dua,
AU  - T.
AU  - Ross,
AU  - D.
AU  - A.
AU  - Lai,
AU  - J.
AU  - Skeen,
AU  - S.
DB  - November 2024.enl
DO  - /10.1016/j.jadohealth.2024.09.030
L1  - internal-pdf://2862975178/Psychosocial Interventions for Preventing Ment.pdf
PY  - 2024
SP  - 16
T2  - Journal of Adolescent Health
TI  - Psychosocial Interventions for Preventing Mental Health Conditions in Adolescents With Emotional Problems: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jadohealth.2024.09.030
UR  - https://www.sciencedirect.com/science/article/pii/S1054139X24004646?via%3Dihub
VL  - 16
ER  -
TY  - JOUR
AB  - Objective: The purpose of this review was to synthesize the current literature on the relationship between sleep and physical activity in children and adolescents with neurodevelopmental disorders. 

Methods&lt;: Articles were searched in PubMed, Web of Science, EBSCO, Cochrane, and Embase until April 2024. The meta-analysis was performed using Review Manager 5.3. 

Results: Our results show that measuring sleep parameters by means of different measuring tools yields different results. Most studies have found no association between sleep and physical activity in children with neurodevelopmental disorders, especially when measured subjectively, such as parent reports and sleep logs. Physical activity interventions had a significant effect on sleep efficiency, wake after sleep onset, and sleep duration when measured objectively using instruments such as wrist actigraphy. Meta-analysis showed that children and adolescents with neurodevelopmental disorders who participated in mind-body activities (SMD = -3.01, 95%CI = -4.15~-1.87, p &lt; 0.001, I&lt;sup&gt;2&lt;/sup&gt; = 99%) showed significant improvements in sleep, which were sessions lasting more than 12 weeks (SMD = -1.01, p &lt; 0.01, I&lt;sup&gt;2&lt;/sup&gt; = 97%), performed at least 3 times per week (SMD = -0.81, 95%CI = -1.53~-0.10, p = 0.03, I&lt;sup&gt;2&lt;/sup&gt; = 95%), and lasted for more than 60 min per session (SMD = -1.55, 95%CI = -2.67~-0.43, p = 0.007, I&lt;sup&gt;2&lt;/sup&gt; = 97%). However, the results of these subgroup analyses must be interpreted with caution because of the small number of studies included. 

Conclusion: Our results show that measuring sleep parameters by means of different measuring tools yields different results. There was difficulty in interpreting many of the studies included in this meta-analysis, in view of the non-standardization of protocol, especially the ability range of the cohort, duration of the study, recommended exercises, whether the caregivers or researchers supervised the exercise regime/activity, and the practicality of continuing the exercise long-term by caregivers. 

<b>Systematic review registration</b>: Identifier, CRD42024541300.
AN  - 39193141
AU  - Wang,
AU  - T.
AU  - Li,
AU  - W.
AU  - Deng,
AU  - J.
AU  - Zhang,
AU  - Q.
AU  - Liu,
AU  - Y.
AU  - Zheng,
AU  - H.
DB  - August 2024.enl
DO  - /10.3389/fneur.2024.1438786
L1  - internal-pdf://1096247157/Wang-2024-The impact of the physical activity.pdf
PY  - 2024
SP  - 1438786
T2  - Frontiers in neurology [electronic resource].
TI  - The impact of the physical activity intervention on sleep in children and adolescents with neurodevelopmental disorders: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffneur.2024.1438786
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347421/pdf/fneur-15-1438786.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - CONTEXT&lt;: Mixed evidence exists on whether physical exercise interventions influence intelligence measures in children and adolescents. 

OBJECTIVE: To determine the effect of exercise interventions on intelligence in children and adolescents. 

DATA SOURCES: Relevant articles were identified in PubMed, Web of Science, PsycINFO, and Scopus (until February 22, 2024). 

STUDY SELECTION: Randomized controlled trials assessing the effects of exercise interventions on intelligence in youth (&lt;=19 years). 

DATA EXTRACTION&lt;: A random-effects meta-analysis was performed for intelligence measures reported in &gt;=3 studies. Subanalyses examined the moderating effect of variables such as participants&#039; intelligence quotient (IQ), age, or intervention duration. 

RESULTS: Fourteen randomized controlled trials (n = 3203 participants; age range = 5-14 years) were included. Exercise interventions significantly improved general intelligence compared with control groups (standardized mean difference = 0.54, 95% confidence interval [CI] = 0.11-0.97, P = .01), which corresponded to a mean improvement in the IQ score of 4.0 points (95% CI = 1.44-6.64, P = .01). Significant benefits of exercise interventions were also observed for fluid intelligence (standard mean difference = 0.20, 95% CI = 0.06-0.34, P = .006). Crystallized intelligence could not be meta-analyzed because of a lack of studies. Subanalyses revealed similar benefits in participants with low/borderline versus normal IQ, children versus adolescents, and interventions with different durations. 

LIMITATIONS: The heterogeneity observed in the characteristics of the exercise interventions and the populations included can be a potential confounding factor. <b>CONCLUSIONS</b>: Exercise interventions are associated with improvements in intelligence (including both general and fluid intelligence) in youth.
AN  - 39506553
AU  - Morales,
AU  - J.
AU  - S.
AU  - Valenzuela,
AU  - P.
AU  - L.
AU  - Martinez-de-Quel,
AU  - O.
AU  - Sanchez-Sanchez,
AU  - J.
AU  - L.
AU  - Muntaner-Mas,
AU  - A.
AU  - Erickson,
AU  - K.
AU  - I.
AU  - Carbonell-Baeza,
AU  - A.
AU  - Ortega,
AU  - F.
AU  - B.
AU  - Jimenez-Pavon,
AU  - D.
DB  - Desember 2024.enl
DO  - /10.1542/peds.2023-064771
L1  - internal-pdf://0408090420/6018a716-1553-4bf9-bf54-9ea96130705d.pdf
PY  - 2024
SP  - 01
T2  - Pediatrics
TI  - Exercise Interventions and Intelligence in Children and Adolescents: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1542%2fpeds.2023-064771
UR  - https://publications.aap.org/pediatrics/article-abstract/154/6/e2023064771/199838/Exercise-Interventions-and-Intelligence-in?redirectedFrom=fulltext
VL  - 154
ER  -
TY  - JOUR
AB  - Background: Anxiety and depression symptomatology has increased in the child and adolescent population. Internet-delivered psychological treatments (IDPT) can help to reduce this symptomatology, attending to the largest possible population. Aim: To conduct a systematic review and network meta-analysis of IDPT to reduce anxiety and depression symptoms in children and adolescents. Methods: The search for studies was conducted in SCOPUS, PsycINFO, PSICODOC, PsycARTICLES and Medline, between 2000 and 2022, in December 2022. Studies were selected if they were conducted with a sample of children and/or adolescents with previous symptoms of anxiety and depression, had applied IDPT, and included at least two comparative groups with pretest-posttest measures. Network meta-analyses were separately performed for anxiety and depression outcomes. Publication bias was analyzed using Egger&#039;s test and funnel plots, and mixed-effects meta-regression models were applied to account for heterogeneity. Results: 37 studies were included in the meta-analysis, providing a total of 74 comparative groups. IDPT exhibited low-to-moderate, statistically significant average effect sizes when compared to both inactive and active controls. No statistical significance was found when IDPT was compared with other types of interventions. Discussion: IDPT is recommended to reduce anxiety and depression symptomatology in children and adolescents, but more studies are needed which compare treatments with other types of interventions, such as face-to-face therapy.
AN  - WOS:001275206200001
AU  - L&oacute;pez-Soler,
AU  - C.
AU  - Vicente-Escudero,
AU  - J.
AU  - L.
AU  - L&oacute;pez-L&oacute;pez,
AU  - J.
AU  - A.
AU  - Alc&aacute;ntara,
AU  - M.
AU  - Mart&iacute;nez,
AU  - A.
AU  - Castro,
AU  - M.
AU  - Fern&aacute;ndez,
AU  - V.
AU  - S&aacute;nchez-Meca,
AU  - J.
DB  - August 2024.enl
DO  - 10.1016/j.ijchp.2024.100487
L1  - internal-pdf://2988204941/1-s2.0-S1697260024000528-main.pdf
PY  - 2024
SP  - 11
T2  - International Journal of Clinical and Health Psychology
TI  - Effectiveness of internet-delivered psychological treatments for children and adolescents with anxiety and/or depressive disorders: Systematic review and network meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001275206200001
VL  - 24
ER  -
TY  - JOUR
AB  - **Objective**: This systematic review and meta-analysis aimed to comprehensively evaluate the impact of physical exercise interventions on anxiety, depression, and emotional regulation in children diagnosed with attention deficit hyperactivity disorder (ADHD). **Methods**: A comprehensive search was conducted across multiple databases, including Embase, Web of Science (WOS), PubMed, The Cochrane Library, Wanfang Data, VIP Information, and China National Knowledge Infrastructure (CNKI), from their inception up to July 2024. The search aimed to identify randomized controlled trials (RCTs) investigating the impact of physical exercise on anxiety, depression, and emotional regulation in children diagnosed with ADHD. The Physiotherapy Evidence Database (PEDro) scale was employed to assess the quality of the literature, while the revised Cochrane risk-of-bias tool (ROB-2) was used to evaluate the overall risk of bias. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) profiler method was utilized to further assess the quality of evidence. Meta-analysis, sensitivity analysis, and publication bias testing were performed using Stata 18.0 software. Effect sizes were calculated using the standardized mean difference (SMD) and 95% confidence intervals (CI). **Results**: The analysis included 18 RCTs, encompassing 830 participants. Physical exercise exhibited a significant positive effect on anxiety (SMD = -0.58, p &lt; 0.05), depression (SMD = -0.57, p &lt; 0.05), and emotional regulation (SMD = 1.03, p &lt; 0.05) in children diagnosed with ADHD. Subgroup analysis revealed that exercise programs with monotypic and mixed modalities, short duration, high frequencies, medium duration, and moderate intensities were the most efficacious in ameliorating anxiety symptoms. The mixed exercise program, when conducted for short duration, with low frequencies, medium duration, and moderate intensity was the most effective in alleviating depression symptoms. Exercise programs featuring mixed modalities, longer duration, moderate to high frequencies, shorter duration, and low intensity yielded the most significant improvements in emotional regulation. **Conclusions**: Research demonstrates that physical exercise mitigates anxiety and depression and improves emotional regulation in children with ADHD. A dose-response relationship is evident, correlating with the type, duration, intensity, frequency, and overall exercise duration. <b>Systematic Review Registration</b>: https://www.crd.york.ac.uk/prospero/, PROSPERO identifier (CRD42024571577).
AN  - 39840316
AU  - Song,
AU  - Y.
AU  - Jia,
AU  - S.
AU  - Wang,
AU  - X.
AU  - Wang,
AU  - A.
AU  - Ma,
AU  - T.
AU  - Li,
AU  - S.
AU  - Chen,
AU  - J.
AU  - Guo,
AU  - Z.
AU  - Ding,
AU  - F.
AU  - Ren,
AU  - Y.
AU  - Qin,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fped.2024.1479615
L1  - internal-pdf://0211700067/Song-2024-Effects of physical exercise on anxi.pdf
PY  - 2024
SP  - 1479615
T2  - Frontiers in Pediatrics
TI  - Effects of physical exercise on anxiety depression and emotion regulation in children with attention deficit hyperactivity disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffped.2024.1479615
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11747210/pdf/fped-12-1479615.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **Background**: In 2016, globally, suicide was the second leading cause of death amongst those aged 15 to 29 years. Self‐harm is increasingly common among young people in many countries, particularly among women and girls. The risk of suicide is elevated 30‐fold in the year following hospital presentation for self‐harm, and those with suicidal ideation have double the risk of suicide compared with the general population.Self‐harm and suicide in young people are significant public health issues that cause distress for young people, their peers, and family, and lead to substantial healthcare costs. Educational settings are widely acknowledged as a logical and appropriate place to provide prevention and treatment. A comprehensive, high‐quality systematic review of self‐harm and suicide prevention programmes in all education settings is thus urgently required. This will support evidence‐informed decision making to facilitate rational investment in prevention efforts in educational settings. Suicide and self‐harm are distressing, and we acknowledge that the content of this review is sensitive as the data outlined below represents the lived and living experience of suicidal distress for individuals and their caregivers.**Objectives**: To assess the effects of interventions delivered in educational settings to prevent or address self‐harm and suicidal ideation in young people (up to the age of 25) and examine whether the relative effects on self‐harm and suicide are modified by education setting.**Search methods**: We searched the Cochrane Common Mental Disorders Specialised Register, CENTRAL, The Cochrane Database of Systematic Reviews, Ovid MEDLINE, PsycINFO, ERIC, Web of Science Social Science Citation Index, EBSCO host Australian Education Index, British Education Index, Educational Research Abstracts to 28 April 2023.**Selection criteria**: We included trials where the primary aim was to evaluate an intervention specifically designed to reduce self‐harm or prevent suicide in an education setting. Randomised controlled trials (RCTs), cluster‐RCTs, cross‐over trials and quasi‐randomised trials were eligible for inclusion. Primary outcomes were self‐harm postintervention and acceptability; secondary outcomes included suicidal ideation, hopelessness, and two outcomes co‐designed with young people: better or more coping skills, and a safe environment, with more acceptance and understanding.**Data collection and analysis**: We used standard methodological procedures as expected by Cochrane. Two review authors independently selected studies, extracted data, and assessed risk of bias. We analysed dichotomous data as odds ratios (ORs) and continuous data as standardised mean differences (SMDs) with 95% confidence intervals (CIs). We conducted random‐effects meta‐analyses and assessed certainty of evidence using the GRADE approach. For co‐designed outcomes, we used vote counting based on the direction of effect, as there is a huge variation in the data and the effect measure used in the included studies.**Main results**: We included 51 trials involving 36,414 participants (minimum 23; maximum 11,100). Twenty‐seven studies were conducted in secondary schools, one in middle school, one in primary school, 19 in universities, one in medical school, and one across education and community settings. Eighteen trials investigated universal interventions, 11 of which provided data for at least one meta‐analysis, but no trials provided data for self‐harm postintervention. Evidence on the acceptability of universal interventions is of very low certainty, and indicates little or no difference between groups (OR 0.77, 95% CI 0.36 to 1.67; 9 studies, 8528 participants). Low‐certainty evidence showed little to no effect on suicidal ideation
AU  - Vartika
AU  - S.,
AU  - Marshall,
AU  - D.
AU  - Fortune,
AU  - S.
AU  - Prescott,
AU  - A.
AU  - E.,
AU  - Boggiss,
AU  - A.,
AU  - Macleod,
AU  - E.,
AU  - Mitchell,
AU  - C.,
AU  - Clarke,
AU  - A.,
AU  - Robinson,
AU  - J.,
AU  - Witt,
AU  - K.
AU  - G.
AU  - Hawton,
AU  - K.,
AU  - Hetrick,
AU  - S.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1002/14651858.CD013844.pub2
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Prevention of self‐harm and suicide in young people up to the age of 25 in education settings
ER  -
TY  - JOUR
AB  - **Background**
Emotional and behavioural difficulties (EBD) in children are common, characterised by externalising or internalising behaviours that can be highly stable over time. EBD are an important cause of functional disability in childhood, and predictive of poorer psychosocial, academic, and occupational functioning into adolescence and adulthood. The prevalence, stability, and long‐term consequences of EBD highlight the importance of intervening in childhood when behavioural patterns are more easily modified.

Multiple factors contribute to the aetiology of EBD in children, and parenting plays an important role. The relationship between parenting and EBD has been described as bidirectional, with parents and children shaping one another&rsquo;s behaviour. One consequence of bidirectionality is that parents with insufficient parenting skills may become involved in increasingly negative behaviours when dealing with non‐compliance in children. This can have a cyclical effect, exacerbating child behavioural difficulties and further increasing parental distress.

Behavioural or skills‐based parenting training can be highly effective in addressing EBD in children. However, emotional dysregulation may intercept some parents&#039; ability to implement parenting skills, and there is recognition that skills‐based interventions may benefit from adjunct components that better target parental emotional responses. Mindful parenting interventions have demonstrated some efficacy in improving child outcomes via improvements in parental emotion regulation, and there is potential for mindfulness training to enhance the effectiveness of standard parent training programmes.

**Objectives**
To assess the effectiveness of mindfulness‐enhanced parent training programmes on the psychosocial functioning of children (aged 0 to 18 years) and their parents.

**Search methods**
We searched the following databases up to April 2023: the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, CINAHL Plus, PsycINFO, Sociological Abstracts, Social Sciences Citation Index, Conference Proceedings Citation Index &ndash; Social Science &amp; Humanities, AMED, ERIC, ProQuest Dissertations &amp; Theses, Cochrane Database of Systematic Reviews, Campbell Collaboration Library of Systematic Reviews, as well as the following trials registers: ClinicalTrials.gov and the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP). We also contacted organisations/experts in the field.

**Selection criteria**
We included randomised and quasi‐randomised trials. Participants were parents or caregivers of children under the age of 18. The intervention was mindfulness‐enhanced parent training programmes compared with a no‐intervention, waitlist, or attentional control, or a parent training programme with no mindfulness component. The intervention must have combined mindfulness parent training with behavioural or skills‐based parent training. We defined parent training programmes in terms of the delivery of a standardised and manualised intervention over a specified and limited period, on a one‐to‐one or group‐basis, with a well‐defined mindfulness component. The mindfulness component must have included mindfulness training (breath, visualisation, listening, or other sensory focus) and an explicit focus on present‐focused attention and non‐judgemental acceptance.

**Data collection and analysis**
We followed standard Cochrane procedures.

**Main results**
Eleven studies met our inclusion criteria, including one ongoing study. The studies compared a mindfulness‐enhanced parent training programme with a no‐treatment, waitlist, or attentional control (2 studies); a parent training programme with no mindfulness component (5 studies); both a no‐treatment, waitlist, or attentional control and a parent training programme with no mindfulness component (4 studies). We assessed all studies as being at an unclear or high risk of bias across multiple domains. We pooled child and parent outcome data from 2118 participants to produce effect estimates. No study explicitly reported on self‐compassion, and no adverse effects were reported in any of the studies.

Mindfulness‐enhanced parent training programmes compared to a no‐treatment, waitlist, or attentional control

Very low certainty evidence suggests there may be a small to moderate postintervention improvement in child emotional and behavioural adjustment (standardised mean difference (SMD) &minus;0.46, 95% confidence interval (CI) &minus;0.96 to 0.03; P = 0.06, I2 = 62%; 3 studies, 270 participants); a small improvement in parenting skills (SMD 0.22, 95% CI 0.06 to 0.39; P = 0.008, I2 = 0%; 3 studies, 587 participants); and a moderate decrease in parental depression or anxiety (SMD &minus;0.50, 95% CI &minus;0.96 to &minus;0.04; P = 0.03; 1 study, 75 participants). There may also be a moderate to large decrease in parenting stress (SMD &minus;0.79, 95% CI &minus;1.80 to 0.23; P = 0.13, I2 = 82%; 2 studies, 112 participants) and a small improvement in parent mindfulness (SMD 0.21, 95% CI &minus;0.14 to 0.56; P = 0.24, I2 = 69%; 3 studies, 515 participants), but we were not able to exclude little to no effect for these outcomes.

Mindfulness‐enhanced parent training programmes compared to parent training with no mindfulness component

Very low certainty evidence suggests there may be little to no difference postintervention in child emotional and behavioural adjustment (SMD &minus;0.09, 95% CI &minus;0.58 to 0.40; P = 0.71, I2 = 64%; 5 studies, 203 participants); parenting skills (SMD 0.13, 95% CI &minus;0.16 to 0.42; P = 0.37, I2 = 16%; 3 studies, 319 participants); and parent mindfulness (SMD 0.11, 95% CI &minus;0.19 to 0.41; P = 0.48, I2 = 44%; 4 studies, 412 participants). There may be a slight decrease in parental depression or anxiety (SMD &minus;0.24, 95% CI &minus;0.83 to 0.34; P = 0.41; 1 study, 45 participants; very low certainty evidence), though we cannot exclude little to no effect, and a moderate decrease in parenting stress (SMD &minus;0.51, 95% CI &minus;0.84 to &minus;0.18; P = 0.002, I2 = 2%; 3 studies, 150 participants; low certainty evidence).

**Authors&#039; conclusions**
Mindfulness‐enhanced parenting training may improve some parent and child outcomes, with no studies reporting adverse effects. Evidence for the added value of mindfulness training to skills‐based parenting training programmes is suggestive at present, with moderate reductions in parenting stress. Given the very low to low certainty evidence reviewed here, these estimates will likely change as more high‐quality studies are produced.
AN  - CD012445
AU  - Featherston,
AU  - R.
AU  - Barlow,
AU  - J.
AU  - Song,
AU  - Y.
AU  - Haysom,
AU  - Z.
AU  - Loy,
AU  - B.
AU  - Tufford,
AU  - L.
AU  - Shlonsky,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/14651858.CD012445.pub2
KW  - *Drug-Related Side Effects and Adverse Reactions
KW  - *Mindfulness
KW  - Adolescent
KW  - Child
KW  - Emotions
KW  - Humans
KW  - Parenting
KW  - Parents
L1  - internal-pdf://2117148684/Featherston_et_al-2024-Cochrane_Database_of_Sy.pdf
N1  - [Developmental, Psychosocial and Learning Problems]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Mindfulness‐enhanced parenting programmes for improving the psychosocial outcomes of children (0 to 18 years) and their parents
UR  - http://dx.doi.org/10.1002/14651858.CD012445.pub2
ER  -
TY  - JOUR
AB  - Adolescent aggressive behavior has increasingly become a central issue affecting the safety of both school campuses and the broader society. Despite the existence of numerous community interventions targeting this issue, there has been a paucity of efforts to consolidate the findings on the effectiveness of community-based programs in preventing aggressive behavior. This meta-analysis sought to address this gap by reviewing and assessing the impact of community-based initiatives on reducing adolescent aggression. A thorough search was carried out on 12 electronic databases: EBSCO, ERIC, PubMed, PsycINFO, MEDLINE, EMBASE, Scopus, Web of Science, ProQuest Dissertations and Theses, the China National Knowledge, Wanfang Databases, and China Science and Technology Journal Database. Sixteen studies were finalized, and meta-analyses were performed using a random effect model on RevMan v5.4 software developed by Cochrane. The analysis encompassed 16 published studies, involving a total of 2,585 participants. The key components of existing programs for aggression reduction included providing behavioral skills and training for adolescents, employing a problem-solving approach to address behavioral issues, offering psychological treatment, and emphasizing community supervision. The results indicate a significant positive effect of community-based interventions on aggression reduction (standardized mean difference = -0.26, 95% confidence intervals [-0.39, -0.13], Z = 3.84, p &lt; .001). The subgroup analyses revealed that the intervention&#039;s effectiveness was moderated by the duration of the intervention, its theoretical foundation, and the sample size. This study furnishes empirical evidence supporting the enhancement of policies and practices to foster community engagement in mitigating aggressive behavior.
AN  - 38293961
AU  - Jiang,
AU  - S.
AU  - Chen,
AU  - Y.
AU  - Wang,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/15248380241227986
L1  - internal-pdf://1999208121/jiang-et-al-2024-effectiveness-of-community-ba.pdf
PY  - 2024
SP  - 15248380241227986
T2  - Trauma Violence &amp; Abuse
TI  - Effectiveness of Community-Based Programs on Aggressive Behavior Among Children and Adolescents: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38293961
UR  - https://journals.sagepub.com/doi/10.1177/15248380241227986
ER  -
TY  - JOUR
AB  - Behavioural Activation (BA)-a brief therapy based on the scheduling of enjoyable, purposeful and rewarding activities-is an effective and cost-effective treatment for depression in adults that shows promise for children and adolescents. We provide an update on a previous systematic review of evidence on BA-delivered in-person, telephone, or online-for depression and comorbid anxiety in children and adolescents. We conducted systematic literature searches in 6 databases up to February 2024. We included all study designs evaluating BA with participants up to 18 years old with diagnosable depression, as established by a validated screening tool or diagnostic manual. We used the Moncrieff Scale and the Cochrane Risk of Bias tool to assess study quality. We summarised the findings of all study types with a narrative synthesis and of randomised controlled trials (RCTs) with a meta-analysis. Overall, 24 studies (6 RCTs, 18 pre-post evaluations, n = 2,758) met our inclusion criteria. A meta-analysis of 4 RCTs (n = 156) showed that BA has a small effect of 0.24 (Hedge&#039;s adjusted g) in reducing depression symptoms compared to a waiting-list control, usual care and other therapies. Online and telephone-facilitated BA was shown to be feasible in 3 studies and effective in 1. Outcomes on comorbid anxiety were mixed. No economic evaluations met our inclusion criteria. BA shows sufficient promise as an intervention for reducing depression symptoms in children and adolescents to justify the need for further RCTs, providing that five conditions are met: studies are powered to detect a minimal clinically important difference; BA materials are fit-for-purpose to produce clinically meaningful change; follow-ups are longer than 6 months; primary outcomes are child-reported; and intervention costs, resource use and adverse events are reported.
AN  - 38615316
AU  - Tindall,
AU  - L.
AU  - Kerrigan,
AU  - P.
AU  - Li,
AU  - J.
AU  - Hayward,
AU  - E.
AU  - Gega,
AU  - L.
DB  - April 24.enl
DO  - /10.1007/s00787-024-02429-3
L1  - internal-pdf://3808647170/Tindall-2024-Is behavioural activation an effe.pdf
PY  - 2024
SP  - 14
T2  - European Child &amp; Adolescent Psychiatry
TI  - Is behavioural activation an effective treatment for depression in children and adolescents? An updated systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs00787-024-02429-3
UR  - https://link.springer.com/content/pdf/10.1007/s00787-024-02429-3.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - **Importance:** 
Children and adolescents with neurodevelopmental disorders experience mental health issues and are encouraged to be brought together in real-life treatment. However, physical activity, which is a promising method for boosting mental health, has only been examined in children and adolescents with certain types of neurodevelopmental disorders. 

**Objective:** 
To examine the association of physical activity interventions with mental health (ie, cognitive function, psychological well-being, internalizing, and externalizing problems) in children and adolescents with neurodevelopmental disorders and to identify possible moderators. 

**Data Sources:** 
Studies were searched from inception to May 2023 through Web of Science, PsycINFO, SPORTDiscus, MEDLINE, CINAHL, and ERIC. 

**Study Selection:** 
Randomized clinical trials or nonrandomized designs applying physical activity interventions and reporting at least 1 mental health outcome in children and adolescents aged 5 to 17 years with neurodevelopmental disorders were included. Two independent reviewers selected and assessed the studies. 

**Data Extraction and Synthesis:** 
Random multilevel meta-analysis using Hedges g was performed. Data extraction and risk-of-bias assessment were conducted by multiple reviewers. Heterogeneity, publication bias, sensitivity analysis, and moderator analysis were examined to substantiate the results. 

**Main Outcomes and Measures:** 
The main outcomes were mental health related to cognitive function, psychological well-being, internalizing, or externalizing problems measured by neurocognitive tasks or subjective questionnaires. 

**Results:** 
A total of 76 studies involving 3007 participants were included in systematic review, 59 of which were used for meta-analysis. The findings indicated that physical activity interventions were associated with significant benefits for overall mental health (g, 0.67; 95% CI, 0.50-0.85), cognitive function (g, 0.74; 95% CI, 0.53-0.95), psychological well-being (g, 0.56; 95% CI, 0.16-0.96), internalizing (g, 0.72; 95% CI, 0.34-1.10), and externalizing problems (g, 0.58; 95% CI, 0.28-0.89). Moderators were also identified: frequency, total sessions, and total duration for overall mental health; total sessions, and total duration for cognitive function; session duration and frequency for psychological well-being; physical activity type for internalizing problems; and session duration for externalizing problems. Moderator analyses showed that type of neurodevelopmental disorder did not modify the associations between physical activity and overall mental health or its subgroups. 

**Conclusions and Relevance:** 
The findings in this study suggest that children and adolescents with different types of neurodevelopmental disorders may be grouped together when performing physical activity interventions, which were confirmed to be beneficial to overall mental health and its subgroups in this new diagnostic population, but that physical activity interventions should be tailored when targeting different mental health domains.
AN  - 38285440
AU  - Liu,
AU  - C.
AU  - Liang,
AU  - X.
AU  - Sit,
AU  - C.
AU  - H.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1001/jamapediatrics.2023.6251
L1  - internal-pdf://4145119936/Liu-2024-Physical Activity and Mental Health i.pdf
PY  - 2024
SP  - 29
T2  - Jama Pediatrics
TI  - Physical Activity and Mental Health in Children and Adolescents With Neurodevelopmental Disorders: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38285440
UR  - https://jamanetwork.com/journals/jamapediatrics/article-abstract/2814312
UR  - https://watermark.silverchair.com/jamapediatrics_liu_2024_oi_230093_1706201886.13081.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA1MwggNPBgkqhkiG9w0BBwagggNAMIIDPAIBADCCAzUGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMUuv30yio0p6x320KAgEQgIIDBudv6vBclS3Kv9nwFLQzY-EsPIb6a6ZIb_KLB1vDbj8_EEX761Bfg1Vk6vMWCNYCBEw4HTx58cxXiyMS_52RVJu6tRQaLHvXuQjlxJVA3W92ozf2aTu3AGuCAwXpJmsRu2fOmA_R8m2Zr-gWKl9v8EJmqg2EbWsUQEeMs3L-GxvsWm7luG_-6vh-1A9p6VGKkj7BjHkBBOI-_hYhGFH5hvSbX1fOdwTe56uqn-1PpzR3sGHC3DlSS8EO-Jpef6Fcdj_pSIEd2gMfjsB2U3PaAaFDnCwNCHCLekP_cD4Zi91Mum7QTInxI8QOjSFAPAaE8oT_DGUCFNOjuvYPr13kW3nww0uLhQUTS8xr6jdKeAVmWyEIW3QsfJK8TyrtklK5O7Esfneg-Y2bPDOk66IrjJfczYNIBkI-Hzpi5CPb-U2hZ-0KHtuAWswSe2lYuMQftzMCtmV1h_zQTQBlV_PgthuXSvn4-RbGId-wsEQW2cXnQVe7X8VJsE6TrPZ9cLwakd2xqqxVdgIK4orZXAs6B0q9JPth3oTc-pKVU9YJBz92nl9sgqvBNL1iErsKF1dreLHSUMCkeyTGjm_UlutUp0GdrR45kQFu1hDlGisf1IbGg2iLlPqVfle10tVgFzOBHNGDMX2oY0YowTDYEs_vwws_ymSNrZpT3-X_zak_sLHLoXmxtYB_FpDT39kfX4QBT1HLOrme2yBc5hvQPPhv93Q-IK16rgtU7PjEVxZusVdaXNgPb9CGv8G_9xDH_sbNfImQo39JWVXybm7Xkf2LOwpBIqMirtwnYiGUx-Gm0w72DJVAVM7eXCy8h1YdU0pHIgCA6aICN54eqH0gRy5Mttd9U3VYb9sWH-Oqp4lVYY9_MH07uYrGvK3QyJ5nw3tnHlMAXy6soqUzI4DHAJnBRYK8y7x3QW-1Tie0l8qdkjybsKF_qJFU4usEIy5DFnm3u98KGDAkSlok605Ea381KbOKukRsw6bUtToTfytTVbNaxtymnx3M-Ukxx8CUrLpnbPUUJ7AgLg
VL  - 29
ER  -
TY  - JOUR
AB  - **Background:** 
To bridge the gap in adolescent psychotherapy created by the increasing need for mental health interventions and the limited possibilities of in-person treatment during the pandemic, many health care providers opted to offer online mental health care programs. As a result, the number of mental health apps available in app stores experienced a sharp increase during the COVID-19 pandemic. 

**Objective:** 
The aim of the current review is to provide an overview of feasibility and effectiveness studies testing mobile applications in adolescent psychotherapy during the peak phase of the COVID-19 pandemic. 

**Methods:** 
We conducted a literature search in Pubmed, PsychInfo, Google Scholar, OpenSIGLE and OpenGREY for papers published from June 2020 to June 2023. Studies were included if they evaluated app-based interventions intended for psychotherapeutic treatment and targeted adolescents between 12 and 27 years of age with symptoms of psychological disorders. The quality of each study was assessed using the Systematic Assessment of Quality in Observational Research (SAQOR). Effectiveness outcomes were analyzed by vote counting and calculating a binomial probability test. 

**Results:** 
The search yielded 31 relevant studies that examined 27 different apps with a total of 1,578 adolescent participants. Nine articles were primary effectiveness studies and 22 focused on feasibility measures as primary outcome. There was evidence that mental health apps influenced adolescents&#039; psychotherapy, with 83% of the studies with effectiveness outcomes favoring the intervention (p = 0.002). Sixty-one percent of the included studies were rated at low or very low quality. 

**Conclusions:** 
The pandemic has given apps a firm and important role in healthcare that will probably continue to expand in the future. To ensure that mental health apps are truly effective and beneficial for adolescents&#039; psychotherapy, we need a standardized measurement of quality features of mental health apps and higher quality app evaluation studies. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=406455, PROSPERO International Prospective Register of Systematic Reviews [CRD42023406455].
AN  - 38420028
AU  - Wullner,
AU  - S.
AU  - Hermenau,
AU  - K.
AU  - Krutkova,
AU  - M.
AU  - Petras,
AU  - I.
AU  - K.
AU  - Hecker,
AU  - T.
AU  - Siniatchkin,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fpubh.2024.1345808
L1  - internal-pdf://1308191082/Wullner-2024-Mobile applications in adolescent.pdf
PY  - 2024
SP  - 1345808
T2  - Frontiers in Public Health
TI  - Mobile applications in adolescent psychotherapy during the COVID-19 pandemic: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=38420028
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10899334/pdf/fpubh-12-1345808.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - Objective: The objective of this systematic review and meta-analysis was to evaluate the overall efficacy of cognitive behavioral therapy for insomnia (CBT-I) in treating insomnia in adolescents, and to examine the efficacy of CBT-I on different sleep-related outcomes in this population.

Methods: Randomized controlled trials (RCTs) of CBT-I on insomnia in adolescents were identified using electronic databases and manual searches. The Revised Cochrane risk-of-bias tool for randomized trials (RoB 2) was used to assess risk of bias in RCTs. A standardized mean difference (SMD) with a 95% confidence interval (CI) was used to combine effect sizes. A sensitivity analysis was performed for each outcome using a stepwise elimination method to assess whether the pooled results were significantly affected by individual studies.

Results: The analysis included 8 RCTs involving a total of 599 participants. The meta-analysis indicated that marked and statistically significant improvements in insomnia (SMD = -1.06; 95% CI -1.65 to -0.47; p &lt; 0.01), sleep onset latency (SMD = -0.99; 95% CI -1.65 to -0.32; p &lt; 0.01), total sleep time (SMD = 0.50; 95% CI 0.10 to 0.90; p = 0.01), and sleep efficiency (SMD = 0.57; 95% CI 0.26 to 0.87; p &lt; 0.01) were observed at post-treatment time point following CBT-I. At follow-up time point, a statistically significant improvement in insomnia (SMD = -0.79; 95% CI -1.42 to -0.17; p = 0.01) was observed following CBT-I. 

Conclusion: CBT-I was effective in improving insomnia in adolescents and some sleep-related outcomes, including sleep onset latency, total sleep time, and sleep efficiency. CBT-I was characterized by low risk and high therapeutic benefits and could serve as alternative or adjuvant approaches to medication for the treatment of insomnia. Considering the advantages in terms of safety and efficacy, CBT-I should be the preferred intervention for the treatment of insomnia in adolescents. 

Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, CRD42024526102.
AN  - 39628800
AU  - Mei,
AU  - Z.
AU  - Cai,
AU  - C.
AU  - Luo,
AU  - S.
AU  - Zhang,
AU  - Y.
AU  - Lam,
AU  - C.
AU  - Luo,
AU  - S.
DB  - Desember 2024.enl
DO  - /10.3389/fpubh.2024.1413694
L1  - internal-pdf://1713763851/Mei-2024-The efficacy of cognitive behavioral.pdf
PY  - 2024
SP  - 1413694
T2  - Frontiers in Public Health
TI  - The efficacy of cognitive behavioral therapy for insomnia in adolescents: a systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.3389%2ffpubh.2024.1413694
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11613502/pdf/fpubh-12-1413694.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - The objective was to assess the effectiveness of psychosocial interventions in preventing gang membership and gang-related crime among children and young adults under the age of 30. We performed a systematic review and synthesized interventions targeting universal, selective, and indicated populations published between January 2000 and April 2023. We included 42 (seven randomized, 12 nonrandomized, 23 controlled interrupted time series) studies evaluating 33 unique psychosocial interventions. Synthesis without meta-analysis found a preventive effect of psychosocial interventions in middle schools on gang membership. Furthermore, meta-analysis found that focused deterrence strategies prevented gang-involved violence, and that psychosocial support during probation decreased crime recidivism. This systematic review found significant effects of four psychosocial interventions compared to control in reducing future criminality, especially gun violence, among children and young adults. The findings are discussed regarding policy implications and ethical considerations.
AN  - WOS:001382509700001
AU  - Mellgren,
AU  - C.
AU  - Rostami,
AU  - A.
AU  - Gerell,
AU  - M.
AU  - Sturup,
AU  - J.
AU  - Hartvigsson,
AU  - T.
AU  - Munthe,
AU  - C.
AU  - Bring,
AU  - J.
AU  - Hellberg,
AU  - U.
AU  - Johnsson,
AU  - A.
AU  - K.
AU  - Fundell,
AU  - S.
AU  - Sundell,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1177/10497315241305779
L1  - internal-pdf://1805460363/46b7556f-604a-4e5f-b26e-6887c93f499a.pdf
PY  - 2024
SP  - 21
T2  - Research on Social Work Practice
TI  - Psychosocial Interventions Preventing Gang-Related Crime Among Young People: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001382509700001
UR  - https://journals.sagepub.com/doi/10.1177/10497315241305779
ER  -
TY  - JOUR
AB  - Importance: Viloxazine is a novel nonstimulant medication approved for the treatment of attention-deficit/hyperactivity disorder (ADHD). 

Objectives: To investigate the whether viloxazine is associated with effective and acceptable outcomes when treating children and adolescents with ADHD and to evaluate these outcomes&#039; associations with viloxazine doses and duration of treatment. 

Data Sources: The MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), Embase, PsycINFO, and ClinicalTrial.gov databases were searched from database inception to June 23, 2024. 

Study Selection: Two reviewers independently screened for double-blind, fixed-dose randomized clinical trials (RCTs) that compared viloxazine with placebo for pediatric patients with ADHD. 

Data Extraction and Synthesis: The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guideline. Data extraction was completed independently by 2 authors and cross-checked for errors. Random-effects pairwise and dose-response meta-analyses were conducted.

 Main Outcomes and Measures: The primary outcome was the improvement of ADHD symptoms (measured by ADHD Rating Scale-5), and the secondary outcomes were all-cause discontinuation, dropout due to adverse effects, and serious adverse effects. 

Results: A total of 5 dose-response RCTs were included, with 1560 participants (1011 [64.8%] male; mean [SD] age, 10.6 [6.7] years). Viloxazine was associated with better outcomes in ADHD treatment compared with placebo (mean difference, 5.47 points; 95% CI, 4.03-6.91 points). The dose-response curve was bell-shaped, suggesting that doses greater than 400 mg or greater than 7 mg/kg might not be associated with more efficacy. The temporal trends analysis showed ascent curves tapering off at approximately weeks 4 to 6. The curve for 100 mg/d declined more rapidly, while the curves for 200 mg/d and 400 mg/d declined more gradually. The overall discontinuation rate due to adverse effects was 4.15% in the viloxazine group (45 of 1084), while viloxazine compared with placebo was associated with 2.48-fold higher risk of discontinuation due to adverse effects (risk ratio, 2.48; 95% CI, 1.26-4.88).

Conclusions and relevance: In this meta-analysis, viloxazine was associated with better efficacy in treating children and adolescents with ADHD than placebo. A moderate dose (200-400 mg or 6-8 mg/kg) may provide optimal treatment outcomes. Future studies are warranted to assess the long-term effect of viloxazine. Viloxazine was relatively well tolerated for children and adolescents with ADHD.
AN  - 39560942
AU  - Yu,
AU  - C.
AU  - L.
AU  - Kao,
AU  - Y.
AU  - C.
AU  - Thompson,
AU  - T.
AU  - Stubbs,
AU  - B.
AU  - Tseng,
AU  - P.
AU  - T.
AU  - Hsu,
AU  - C.
AU  - W.
AU  - Yang,
AU  - F.
AU  - C.
AU  - Tu,
AU  - Y.
AU  - K.
AU  - Hsu,
AU  - T.
AU  - W.
AU  - Liang,
AU  - C.
AU  - S.
DB  - November 2024.enl
DO  - /10.1001/jamanetworkopen.2024.45885
L1  - internal-pdf://3647701211/Yu-2024-Response Trajectories and Temporal Tre.pdf
PY  - 2024
SP  - e2445885
T2  - Jama Network Open
TI  - Response Trajectories and Temporal Trends of Viloxazine Treatment for Young People With ADHD: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1001%2fjamanetworkopen.2024.45885
UR  - https://watermark.silverchair.com/yu_2024_oi_241308_1731422423.04208.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAy4wggMqBgkqhkiG9w0BBwagggMbMIIDFwIBADCCAxAGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMKA4EJzJOHPltsoVYAgEQgIIC4a1JdZ2hQPbvUyDiSaJVbch_9Ecydj4Li875gdLp_CM5mB1pVGNDrHO2wb_UXalBlu7z3uAA9gwQdNYOyJMNsCKm0D89l4z1CnhBMtbJHFTZOM3ooOUplltW4aOm52G_5z0j9FICQweskGUFK0ME6vhOkwWyRpkLEh9QTcrXAG9c85NCho9u2XdcmMZIRR9Yy4hztqvcRc8Jvv-xkIRh1hbeYS1F_VlaLU_iHh18IUiTvjDoc96EH1Hfev0PMpD4qALzCXEbrHwxj5nszBeF_MxpX97F8RtotZw0g2aJEM-uQrPs_W41rTxhgjImGxhB7roV2TpWXg2Uuc_YJBB6KylJ0ooFECI4Ih43MgmZI3rjxEYiMp78bgqq9xr0empPwT8GcrIPeu92JlitZCZ-0yEkv40pxtSv-V7C5o0ju0clDYBBBvz9TzcOuzD29TAthkUZvCj9U-lnK1t5B9gLDfW_Hk6ph38_ln_ak3gq6eDDYyxC7N1ZeD0fx4GED187zSUEd5WEuJ8jL60w-TC-Z3y2tGB5-cd2yaXdYSU0EYSPM4WDZi8IzCrJXmHWoCgUNlpyBODHCi_nksJQqrqH-n1OD61BAvQQyGJvxLGGKcSZeHTklJf7H7NIsM6e8eZ5oRUJOJB5g4da6cfOg8e_qqIpRzwztjZnCjILBUoevoCJA2CR_1e13Zr0S5sy4FMVPDtvWSporcC-iTt3BXz_2Rvwt-NwqfCPsnCmuL9lyTmcqCxXmf8zbQufXSNAUeRhMhq0ER6B2TJwZANIgH3V5erfIiS3xWNy50eI3KjIeM03rcmlZjMH1e8D68U_oe9vtmXkfxrQQbylXMQSH5zimcK-t667iFgwFD75c_kYQBYeLt7juFvrR5JW3kccTrEyRI5Ds5Xa-9baM8awVuNyg8tAjYvvsHTyN4DTGpnI6V3F1v3gSki1JqFB81MzREpSEv7ydEAjQmLAcU-c0IGblOOC
VL  - 7
ER  -
TY  - JOUR
AB  - Background
High-income countries offer social assistance (welfare) programs to help alleviate poverty for people with little or no income. These programs have become increasingly conditional and stringent in recent decades based on the premise that transitioning people from government support to paid work will improve their circumstances. However, many people end up with low-paying and precarious jobs that may cause more poverty because they lose benefits such as housing subsidies and health and dental insurance, while incurring job-related expenses. Conditional assistance programs are also expensive to administer and cause stigma. A guaranteed basic income (GBI) has been proposed as a more effective approach for alleviating poverty, and several experiments have been conducted in high-income countries to investigate whether GBI leads to improved outcomes compared to existing social programs.

Objectives
The aim of this review was to conduct a synthesis of quantitative evidence on GBI interventions in high-income countries, to compare the effectiveness of various types of GBI versus &ldquo;usual care&rdquo; (including existing social assistance programs) in improving poverty-related outcomes.

Search Methods
Searches of 16 academic databases were conducted in May 2022, using both keywords and database-specific controlled vocabulary, without limits or restrictions on language or date. Sources of gray literature (conference, governmental, and institutional websites) were searched in September 2022. We also searched reference lists of review articles, citations of included articles, and tables of contents of relevant journals in September 2022. Hand searching for recent publications was conducted until December 2022.

Selection Criteria
We included all quantitative study designs except cross-sectional (at one timepoint), with or without control groups. We included studies in high income countries with any population and with interventions meeting our criteria for GBI: unconditional, with regular payments in cash (not in-kind) that were fixed or predictable in amount. Although two primary outcomes of interest were selected a priori (food insecurity, and poverty level assessed using official, national, or international measures), we did not screen studies on the basis of reported outcomes because it was not possible to define all potentially relevant poverty-related outcomes in advance.

Data Collection and Analysis
We followed the Campbell Collaboration conduct and reporting guidelines to ensure a rigorous methodology. The risk of bias was assessed across seven domains: confounding, selection, attrition, motivation, implementation, measurement, and analysis/reporting. We conducted meta-analyses where results could be combined; otherwise, we presented the results in tables. We reported effect estimates as standard mean differences (SMDs) if the included studies reported them or provided sufficient data for us to calculate them. To compare the effects of different types of interventions, we developed a GBI typology based on the characteristics of experimental interventions as well as theoretical conceptualizations of GBI. Eligible poverty-related outcomes were classified into categories and sub-categories, to facilitate the synthesis of the individual findings. Because most of the included studies analyzed experiments conducted by other researchers, it was necessary to divide our analysis according to the &ldquo;experiment&rdquo; stage (i.e., design, recruitment, intervention, data collection) and the &ldquo;study&rdquo; stage (data analysis and reporting of results).

Main Results
Our searches yielded 24,476 records from databases and 80 from other sources. After screening by title and abstract, the full texts of 294 potentially eligible articles were retrieved and screened, resulting in 27 included studies on 10 experiments. Eight of the experiments were RCTs, one included both an RCT site and a &ldquo;saturation&rdquo; site, and one used a repeated cross-sectional design. The duration ranged from one to 5 years. The control groups in all 10 experiments received &ldquo;usual care&rdquo; (i.e., no GBI intervention). The total number of participants was unknown because some of the studies did not report exact sample sizes. Of the studies that did, the smallest had 138 participants and the largest had 8019. The risk of bias assessments found &ldquo;some concerns&rdquo; for at least one domain in all 27 studies and &ldquo;high risk&rdquo; for at least one domain in 25 studies. The risk of bias was assessed as high in 21 studies due to attrition and in 22 studies due to analysis and reporting bias. To compare the interventions, we developed a classification framework of five GBI types, four of which were implemented in the experiments, and one that is used in new experiments now underway. The included studies reported 176 poverty-related outcomes, including one pre-defined primary outcome: food insecurity. The second primary outcome (poverty level assessed using official, national, or international measures) was not reported in any of the included studies. We classified the reported outcomes into seven categories: food insecurity (as a category), economic/material, physical health, psychological/mental health, social, educational, and individual choice/agency. Food insecurity was reported in two studies, both showing improvements (SMD&thinsp;=&thinsp;&minus;0.57, 95% CI: &minus;0.65 to &minus;0.49, and SMD&thinsp;=&thinsp;&minus;0.41, 95% CI: &minus;0.57 to &minus;0.26) which were not pooled because of different study designs. We conducted meta-analyses on four secondary outcomes that were reported in more than one study: subjective financial well-being, self-rated overall physical health, self-rated life satisfaction, and self-rated mental distress. Improvements were reported, except for overall physical health or if the intervention was similar to existing social assistance. The results for the remaining 170 outcomes, each reported in only one study, were summarized in tables by category and subcategory. Adverse effects were reported in some studies, but only for specific subgroups of participants, and not consistently, so these results may have been due to chance.

Authors&#039; Conclusions
The results of the included studies were difficult to synthesize because of the heterogeneity in the reported outcomes. This was due in part to poverty being multidimensional, so outcomes covered various aspects of life (economic, social, psychological, educational, agency, mental and physical health). Evidence from future studies would be easier to assess if outcomes were measured using more common, validated instruments. Based on our analysis of the included studies, a supplemental type of GBI (provided along with existing programs) may be effective in alleviating poverty-related outcomes. This approach may also be safer than a wholesale reform of existing social assistance approaches, which could have unintended consequences.
AU  - Rizvi,
AU  - A.,
AU  - Kearns,
AU  - M.,
AU  - Dignam,
AU  - M.,
AU  - Coates,
AU  - A.,
AU  - Sharp,
AU  - M.
AU  - K.,
AU  - Magwood,
AU  - O.,
AU  - Labelle,
AU  - P.
AU  - R.,
AU  - Elmestekawy,
AU  - N.,
AU  - Rossiter,
AU  - S.,
AU  - Al-Zubaidi,
AU  - A.
AU  - A.
AU  - A.,
AU  - Dewidar,
AU  - O.,
AU  - Idzerda,
AU  - L.,
AU  - Aguilera,
AU  - J.
AU  - M.
AU  - P.,
AU  - Seal,
AU  - H.,
AU  - Little,
AU  - J.,
AU  - Antequera
AU  - Mart&iacute;n,
AU  - A.
AU  - M.,
AU  - Petkovic,
AU  - J.,
AU  - Jull,
AU  - J.,
AU  - Gergyek,
AU  - L.,
AU  - Tanjong
AU  - Ghogomu,
AU  - E.,
AU  - Shea,
AU  - B.,
AU  - Atance,
AU  - C.,
AU  - Ellingwood,
AU  - H.,
AU  - Pollard,
AU  - C.,
AU  - Mbuagbaw,
AU  - L.,
AU  - Wells,
AU  - G.
AU  - A.,
AU  - Welch,
AU  - V.,
AU  - Kristjansson,
AU  - E.
DB  - Juli 2024.enl
DO  - 10.1002/cl2.1414
L1  - internal-pdf://2022277887/Campbell Systematic Reviews - 2024 - Rizvi - E.pdf
PY  - 2024
T2  - Campbell Systematic Reviews
TI  - Effects of guaranteed basic income interventions on poverty-related outcomes in high-income countries: A systematic review and meta-analysis
ER  -
TY  - JOUR
AB  - The acquisition of daily living skills (DLS) represents an important component in establishing independence and increasing the quality of life for individuals diagnosed with autism spectrum disorder. Video prompting has become a popular intervention to teach DLS and researchers have used different perspectives when filming the video (e.g., point-of-view, spectator view). This literature review sought to systematically examine research on the use of the point-of-view perspective when using video prompting to teach DLS to individuals with autism. This review investigated the overall quality of the evidence, based on the What Works Clearinghouse standards for single-case experimental design and used Tau-U to calculate the effects of the interventions. Additionally, the researchers examined and summarized various descriptive variables found within this literature. Overall, point-of-view video prompting produced larger to very large effects. Suggestions for future research and considerations are discussed.
AN  - WOS:001348758700001
AU  - Wertalik,
AU  - J.
AU  - L.
AU  - Duke,
AU  - M.
AU  - L.
AU  - Poole,
AU  - D.
DB  - November 2024.enl
DO  - 10.1177/01626434241298955
L1  - internal-pdf://2755492466/wertalik-et-al-2024-a-systematic-review-of-poi.pdf
PY  - 2024
SP  - 12
T2  - Journal of Special Education Technology
TI  - A Systematic Review of Point-of-View Video Prompting to Teach Daily Living Skills to Individuals With Autism
UR  - &lt;Go to ISI&gt;://WOS:001348758700001
UR  - https://journals.sagepub.com/doi/10.1177/01626434241298955
ER  -
TY  - JOUR
AB  - Background: Camel milk has emerged as a potential complementary therapy for autism spectrum disorder (ASD). 

Aim: This study aimed to gather evidence from randomized controlled trials (RCTs) on the effectiveness of camel milk consumption in improving symptoms and associated measures in children with ASD.

 Methods: Comprehensive searches of multiple databases were conducted up to March 14, 2024, for RCTs that evaluated whether camel milk consumption by children with ASD was more beneficial than the consumption of a control substance. Quality and bias analyses and meta-anlaysis data were synthesized and analyzed. 

Results: Of 136 records identified, 5 RCTs (n n = 299 children) were selected. The mean difference in scores on the childhood autism rating scale (CARS) for the group given camel milk and the control groups was a mean deviation (MD) -0.75, 95% CI-1.97 to 0.47, p = 0.23. The mean difference in CARS scores in the subgroup analyses for raw camel milk was MD-0.95, 95% CI-2.33 to 0.44, p = 0.18 and boiled camel milk MD -0.50, 95% CI-1.93 to 0.93, p = 0.49. A qualitative synthesis found that raw camel milk intake led to improvements in various social behaviors in children with ASD. Camel milk consumption resulted in increased levels of anti-inflammatory, antioxidant, and immunomodulatory biomarkers, with some differences observed between patients given raw camel milk and boiled camel milk. 

Conclusion: Camel milk shows promise in improving social behaviors and certain biochemical markers in children with ASD, although the current meta-analysis did not document a significant statistical difference in CARS scores for the children studied. Future studies should focus on rigorous RCTs and larger sample sizes to substantiate these preliminary findings.
AN  - WOS:001339995600020
AU  - Kandeel,
AU  - M.
AU  - Morsy,
AU  - M.
AU  - A.
AU  - Al
AU  - Khodair,
AU  - K.
AU  - M.
AU  - Alhojaily,
AU  - S.
DB  - November 2024.enl
DO  - 10.5455/OVJ.2024.v14.i9.33
L1  - internal-pdf://0619939089/Kandeel-2024-Meta-analysis of the efficacy of.pdf
PY  - 2024
SP  - 2441-2452
T2  - Open Veterinary Journal
TI  - Meta-analysis of the efficacy of camel milk consumption for improving autism symptoms in children in randomized clinical trials
UR  - &lt;Go to ISI&gt;://WOS:001339995600020
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11563599/pdf/OpenVetJ-14-2441.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - The mental health and wellbeing of children and young people who have been in care, primarily foster care, kinship care or residential care, remains a public health priority. The Care-experienced cHildren and young people&#039;s Interventions to improve Mental health and wEll-being outcomes Systematic review (CHIMES) synthesized evidence for the effectiveness of interventions targeting: subjective wellbeing; mental, behavioral and neurodevelopmental disorders; and suicide-related outcomes. Searches were conducted in 16 bibliographic databases and 22 websites between 1990 and 2022. This was supplemented by citation tracking, screening of relevant systematic reviews, and expert recommendation. We identified 35 interventions, with 44 evaluations via randomized controlled trials. Through meta-analyses, we found that interventions have a small beneficial impact on a variety of mental health outcomes in the short term (0-6 months). Interventions improved total social, emotional, and behavioral problems (d = -0.15, 95% CI [-0.28, -0.02]), social-emotional functioning difficulties (d = -0.18, 95% CI [-0.31, -0.05]), externalizing problem behaviors (d = -0.30, 95% CI [-0.53, -0.08]), internalizing problem behaviors (d = -0.35, 95% CI [-0.61, -0.08]); and depression and anxiety (d = -0.26, 95% CI [-0.40, -0.13]). Interventions did not demonstrate any effectiveness for outcomes assessed in the longer term (&gt;6 months). Certainty of effectiveness was limited by risk of bias and imprecision. There was limited available evidence for interventions targeting subjective wellbeing and suicide-related outcomes. Future intervention design and delivery must ensure that programs are sufficient to activate causal mechanisms and facilitate change. Evaluation research should use a robust methodology. PROSPERO Registration: CRD42020177478.
AN  - 38362816
AU  - Trubey,
AU  - R.
AU  - Evans,
AU  - R.
AU  - McDonald,
AU  - S.
AU  - Noyes,
AU  - J.
AU  - Robling,
AU  - M.
AU  - Willis,
AU  - S.
AU  - Boffey,
AU  - M.
AU  - Wooders,
AU  - C.
AU  - Vinnicombe,
AU  - S.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1177/15248380241227987
L1  - internal-pdf://2952355343/trubey-et-al-2024-effectiveness-of-mental-heal.pdf
PY  - 2024
SP  - 15248380241227987
T2  - Trauma Violence &amp; Abuse
TI  - Effectiveness of Mental Health and Wellbeing Interventions for Children and Young People in Foster, Kinship, and Residential Care: Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38362816
ER  -
TY  - JOUR
AB  - Objective: In recent years, the relationship between nutrition and mental health has gained considerable interest. We identified, synthesized, and appraised all meta-analyses of randomized controlled trials (RCTs) and observational studies reporting on the efficacy of dietary patterns and nutrient supplements in the prevention and treatment of mental disorders in children and adolescents. Methods: Systematic research in MEDLINE, PsycINFO, Scopus, and Cochrane Database of Systematic Reviews was completed on 8 January 2024. Results: Our research found 24 meta-analyses: 14 on RCTs, 8 on observational studies, and 2 combining both. Emerging evidence suggests that omega-3, in particular eicosapentaenoic acid, and Vitamin D may have adjunctive benefits in the treatment of attention deficit hyperactivity disorder (ADHD), while no evidence was found for autism spectrum disorder (ASD). Observational data also indicated that prenatal folic acid supplementation (&gt;400 mu g daily) was associated with a reduced risk of ASD in offspring. In terms of dietary habits, several meta-analyses of observational data revealed that healthy dietary patterns (rich in fruits, vegetables, and fibre, low in saturated fats) during the prenatal period, childhood, and adolescence were linked to a significantly reduced risk of internalizing disorders and externalizing disorders. Conversely, unhealthy dietary habits (high in sugars, saturated animal fats, and industrial foods, low in fruits, vegetables, and fibre) are associated with an elevated risk of these mental health issues. However, the number of available studies on dietary interventions for the treatment of depression, ASD, and ADHD was limited, and the results obtained were either nonsignificant or contradictory. Conclusion: Our findings emphasize the need to establish clear causal relationships between dietary habits and the risk of mental illness in children and adolescents. Moreover, further investigation of the benefits observed with some nutrient supplements (such as omega-3 and vitamin D for ADHD) through larger-scale RCTs is imperative to establish more robust conclusions.
AN  - WOS:001216862300001
AU  - Talib,
AU  - M.
AU  - Rachdi,
AU  - M.
AU  - Papazova,
AU  - A.
AU  - Nicolis,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1177/07067437241248070
L1  - internal-pdf://0298871158/talib-et-al-2024-the-role-of-dietary-patterns-.pdf
PY  - 2024
SP  - 23
T2  - Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie
TI  - The Role of Dietary Patterns and Nutritional Supplements in the Management of Mental Disorders in Children and Adolescents: An Umbrella Review of Meta-Analyses
UR  - &lt;Go to ISI&gt;://WOS:001216862300001
UR  - https://journals.sagepub.com/doi/10.1177/07067437241248070
ER  -
TY  - JOUR
AB  - ABSTRACT: Executive function (EF) development is vital for children and adolescents, with physical activity (PA) playing a key role in its enhancement. Through a systematic review and multilevel meta-analysis, this study investigates the effectiveness of cognitively engaging physical activity (CEPA) over traditional PA in fostering EF in children and adolescents. The research involved 1671 participants across 15 studies to determine if CEPA is superior to PA in enhancing EF and to analyze interventions and dose-response effects. Results demonstrated that CEPA had a more pronounced impact on EF development compared with PA, with a Hedges&#039; g of 0.50 (95% confidence interval, 0.10-0.48), although potentially overestimated due to small-study effects and publication bias. Subgroup analyses did not find notable differences in effectiveness among various intervention types. The most substantial effect was observed with 45-minute interventions, while frequencies less than twice weekly and durations beyond 12 weeks were less effective. These findings suggest that CEPA could be a more efficacious method for advancing EF in youth, indicating a need for larger-scale randomized controlled trial (RCTs) to confirm the results and more accurately estimate their magnitude.
AN  - 39591519
AU  - Teng,
AU  - G.
AU  - Xia,
AU  - H.
AU  - Li,
AU  - Q.
AU  - Chen,
AU  - A.
DB  - November 2024.enl
DO  - /10.1097/DBP.0000000000001330
L1  - internal-pdf://2695920289/Improving Executive Function in Children and A.pdf
PY  - 2024
SP  - 26
T2  - Journal of Developmental &amp; Behavioral Pediatrics
TI  - Improving Executive Function in Children and Adolescents with Cognitive-Engaging Physical Activity: A Systematic Review and Multilevel Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1097%2fDBP.0000000000001330
VL  - 26
ER  -
TY  - JOUR
AB  - **Background and aims:** 
The cultivation of executive functions during early childhood establishes the fundamental underpinning for advanced cognitive development in adulthood. Presently, there remains a degree of controversy surrounding the empirical findings pertaining to the impact of physical activity on the executive functions of young children. This study aimed at elucidating the potential moderating factors influencing the relationship between physical activity and the executive functions of young children. 

**Methods:** 
In this study, we have conducted a meta-analysis encompassing twenty-four experimental studies with a total of 1426 participants. The meta-analysis was conducted using Stata version 17.0 and R version 4.3.2 software, with Hedges&#039;g serving as the chosen effect size metric. 

**Results:** 
The outcomes of our investigation underscore the salient point that physical activity possesses the capacity to enhance the executive functions of young children. Furthermore, it is noteworthy that the developmental impact of physical activity on the executive functions of young children is notably contingent upon the duration of the intervention. The implementation of game-based pedagogical approaches within the realm of sports activities emerges as a particularly potent means to foster the development of executive functions in young children. 

**Conclusions:** 
This meta-analysis serves to proffer quantitative evidence affirming the positive influence of physical activities on the executive functions of young children during their early developmental years. It carries substantial implications for practical application.
AN  - WOS:001218207800001
AU  - Wei,
AU  - Y.
AU  - G.
AU  - Wang,
AU  - L.
AU  - Tang,
AU  - Y.
AU  - Deng,
AU  - H.
AU  - Su,
AU  - J.
AU  - Y.
AU  - Li,
AU  - Q.
AU  - L.
DB  - Juni 24.enl
DO  - 10.1016/j.mhpa.2024.100592
L1  - internal-pdf://1708812999/1-s2.0-S1755296624000188-main.cleaned.pdf
PY  - 2024
SP  - 12
T2  - Mental Health and Physical Activity
TI  - Enhancing young children&#039;s executive function through physical activities: A three-level meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001218207800001
VL  - 26
ER  -
TY  - JOUR
AB  - The psychosocial health of children and adolescents has been particularly affected by the COVID-19 pandemic. Containment measures have restricted social development, education and recreational activities, may have increased family conflicts and, in many cases, led to feelings of loneliness, sleep disturbances, symptoms of anxiety and depression. We conducted a systematic review to identify interventions that seek to ameliorate these detrimental effects of the COVID-19 pandemic and to build resilience in children and adolescents. Literature searches were conducted in the databases MEDLINE, EMBASE, PsycINFO, CENTRAL, WHO COVID-19 Global literature on coronavirus disease and Cochrane COVID-19 Study Register (up to 30 June 2022). The searches retrieved 9557 records of which we included 13 randomized-controlled trials (RCTs) for evidence synthesis. Included studies predominantly implemented online group sessions for school-aged children with either a psychological component, a physical activity component, or a combination of both. A meta-analysis of seven studies on anxiety and five on depressive symptoms provided evidence for a positive effect of interventions by reducing anxiety (Standardized Mean Difference (SMD) (95% CI): - 0.33 (- 0.59; - 0.06)) and depressive symptoms (SMD (95% CI): - 0.26 (- 0.36; - 0.16)) compared to the control interventions. Studies also showed improvements in positive mental health outcomes, such as resilience (n = 2) and mental and psychological wellbeing (n = 2). Exploratory subgroup analyses suggested a greater effectiveness of interventions that (i) are of higher frequency and duration, (ii) enable personal interaction (face-to-face or virtually), and (iii) include a physical activity component. Almost all studies were judged to be at high risk of bias and showed considerable heterogeneity. Further research may focus on the contribution of different intervention components or distinct subgroups and settings, and should examine children and adolescents over longer follow-up periods.
AN  - 37573565
AU  - Wendel,
AU  - F.
AU  - Bender,
AU  - S.
AU  - Breitinger,
AU  - E.
AU  - Coenen,
AU  - M.
AU  - Hummel,
AU  - J.
AU  - Immich,
AU  - G.
AU  - Kirschneck,
AU  - M.
AU  - Klunder,
AU  - V.
AU  - Kunzler,
AU  - A.
AU  - M.
AU  - Lieb,
AU  - K.
AU  - Movsisyan,
AU  - A.
AU  - Li,
AU  - L.
AU  - Y.
AU  - Ravens-Sieberer,
AU  - U.
AU  - Rehfuess,
AU  - E.
AU  - Voss,
AU  - S.
AU  - Jung-Sievers,
AU  - C.
DB  - November 2024.enl
DO  - /10.1007/s00787-023-02280-y
L1  - internal-pdf://3975512095/Wendel-2024-Interventions to build resilience.pdf
PY  - 2024
SP  - 3707-3726
T2  - European Child &amp; Adolescent Psychiatry
TI  - Interventions to build resilience and to ameliorate negative psychosocial effects of the COVID-19 pandemic on children and adolescents: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.1007%2fs00787-023-02280-y
UR  - https://link.springer.com/content/pdf/10.1007/s00787-023-02280-y.pdf
VL  - 33
ER  -
TY  - JOUR
AB  - Introduction: Autism is a neurological disorder that has seen an increase in prevalence in recent years. It is hypothesized that diet may influence mental health and improve the behavioral symptoms of autism. Objectives: The purpose of this study is to examine the effects of gluten -free and casein -free diets on children with autism. Data Sources: International databases such as Google Scholar, PubMed, Cochrane, and Science Direct were searched using keywords including Autism, Gluten -free, Casein, Diet, and Autistic Disorder, without any time restriction Study Selection: Ultimately, 8 articles were selected for the final analysis. Data Extraction: The study revealed that gluten-free/casein-free (GF/CF) diets had a significantly positive effect on the behavior index of autistic children. In terms of the behavior index, the effect size was a standard mean difference (SMD) of -0.27 (P = 0.001) with a 95% confidence interval (CI) of -0.424 to -0.116. A meta -analysis comparing intervention and control groups indicated that the GF/CF diet had an effect size of SMD = -0.27 (P = 0.001) with a 95% CI of -0.429 to -0.112 on the behavior index. Results: The results of these studies were synthesized using the fixed effects model of meta -analysis with STATA version 14. Conclusions: Given the positive impact of the GF/CF diet on improving the behavior of autistic children, this dietary approach can be considered as a means to enhance behavioral symptoms in these children.
AN  - WOS:001181954400007
AU  - Karimi,
AU  - P.
AU  - Deldar,
AU  - M.
AU  - Sayehmiri,
AU  - K.
DB  - April 24.enl
DO  - 10.5812/ijp-140372
L1  - internal-pdf://0537615041/Karimi-2024-The Effects of a Gluten-Free_Casei.pdf
PY  - 2024
SP  - 9
T2  - Iranian Journal of Pediatrics
TI  - The Effects of a Gluten-Free/Casein-Free Diet on Behavioral Indices in Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001181954400007
UR  - https://brieflands.com/articles/ijp-140372.pdf
VL  - 34
ER  -
TY  - JOUR
AB  - To investigate the effect of physical activity (PA) (both general and its type) on self-esteem during and after cancer treatment. A systematic search was conducted across PubMed, Web of Science, Scopus, SPORTDiscuss, and PsycINFO from their inception to February 2024. The systematic review included 32 studies, with 15 studies (13 RCT and 2 quasi-experimental) and 3604 participants (66.7% female) included in the meta-analysis involving controlled trials using a control group and at least one PA intervention group. The study was registered in PROSPERO (CRD42022309771). Risk of bias for RCTs was assessed using the Cochrane Collaboration&#039;s tool for assessing risk of bias (RoB2), and quasi-experimental studies with the Joanna Briggs Institute critical appraisal tool. PA significantly improved self-esteem during and after cancer treatment (pooled SMD = 0.32, p &lt; 0.01). Specifically, aerobic PA (pooled SMD = 0.33, p = 0.04) and mind-body exercise (pooled SMD = 0.70, p = 0.03) had positive effects on self-esteem. Overall, PA interventions improved self-esteem during cancer treatment (pooled SMD = 0.50, p = 0.01) and in PA interventions lasting more than 12 weeks (pooled SMD = 0.44, p = 0.02). In conclusion, PA (specifically, aerobic and mind-body exercises) may have a positive effect on self-esteem during and after cancer treatment, with cancer status and the duration of the intervention being key factors.
AN  - WOS:001348892400015
AU  - Rodriguez-Solana,
AU  - A.
AU  - Gracia-Marco,
AU  - L.
AU  - Cadenas-Sanchez,
AU  - C.
AU  - Redondo-T&eacute;bar,
AU  - A.
AU  - Marmol-Perez,
AU  - A.
AU  - Gil-Cosano,
AU  - J.
AU  - J.
AU  - Llorente-Cantarero,
AU  - F.
AU  - J.
AU  - Ubago-Guisado,
AU  - E.
DB  - November 2024.enl
DO  - 10.1038/s41598-024-74888-2
L1  - internal-pdf://4051795390/Rodriguez-Solan-2024-The effects of physical a.pdf
PY  - 2024
SP  - 16
T2  - Scientific Reports
TI  - The effects of physical activity interventions on self-esteem during and after cancer treatment: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001348892400015
UR  - https://www.nature.com/articles/s41598-024-74888-2.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Autism spectrum disorders (ASD) are characterized by impaired social communication and interactions, as well as constrained and repetitive manifestations of interests and behaviors. Various interventions at cognitive and behavioral levels aim to address impaired social communication and interaction in individuals with ASD. This study systematically explores the transferability of social training in individuals with ASD, guided by the conceptual model known as the FIELD framework (Function, Implement, Ecology, Level, and Durability). Employing the PRISMA methodology, 52 original experiments were included in the study. The transfer analysis, formulated as a conceptual meta-analysis based on the effect sizes, underscores the significant impact of variables including age, severity of autism, intervention tools, intervention intensity, intervention context, and intervention duration on the transferability of social training in individuals with ASD. The transfer of skills was particularly conspicuous among younger individuals, especially in face-to-face interventions, in contrast to digital alternatives. Moreover, cognitive interventions exhibited superior transferability compared to behavioral interventions, especially when administered with a higher intervention dose.
AN  - WOS:001386371500028
AU  - Nejati,
AU  - V.
AU  - Peyvandi,
AU  - A.
AU  - Nazari,
AU  - N.
AU  - Abadi,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1038/s41598-024-83953-9
L1  - internal-pdf://3626774386/Nejati-2024-The effectiveness of social traini.pdf
PY  - 2024
SP  - 23
T2  - Scientific Reports
TI  - The effectiveness of social training in individuals with autism spectrum disorder (ASD): a systematic review and transfer analysis
UR  - &lt;Go to ISI&gt;://WOS:001386371500028
UR  - https://www.nature.com/articles/s41598-024-83953-9.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Objective: Individuals with autism spectrum disorder (ASD) exhibit impaired behavior synchronization, which is associated with social deficits. Numerous studies have demonstrated that rhythm-based interventions can effectively mitigate social deficits by promoting behavioral synchronization in individuals with ASD. Therefore, a review of the current literature is warranted in this field. The objectives of this review were to explore the effects of rhythm-based interventions on overall social skills and to study the differences in the effects of rhythm-based interventions on specific social skills. 

Method: The databases PubMed, Web of Science, Scopus, and Psycinfo were systematically explored until March 2024. A total of eleven research studies, encompassing 408 participants diagnosed with ASD, were incorporated into the meta-analysis. Effect sizes (Hedges&#039; g) were computed for each comparison and amalgamated using random-effects models to evaluate the social skills of individuals with ASD. The methodological quality of each study was evaluated using the Physiotherapy Evidence Database scale(PEDro).

Results: Overall, some valuable observations were made. Rhythm-based interventions had a medium effect on the overall social skills for ASD (Hedges&#039;s=0.681; 95%CI[0.075 to 1.286], P &lt; 0.05). Regarding domain-specific social skills, rhythm-based interventions had a large effect on social interaction (g = 1.299,95% CI [0.508 to 2.091]), a small effect on communication (g = 0.383, 95% CI [0.033 to 0.733], P &lt; 0.05), and a large effect on emotion (g = 1.752, 95% CI [0.294 to 3.210], P &lt; 0.05). However, we found a favorable but non-significant effect (g = 0.125, 95% CI [-0.039 to 0.289], P &gt; 0.05) of rhythm-based interventions on empathy. All study qualities were high (score &gt;= 6) using the Physiotherapy Evidence Database (PEDro) scale assessment. 

Conclusion: This result indicates the importance of rhythm in the clinical rehabilitation of individuals with ASD. We suggest adding appropriate rhythmic elements to clinical interventions, particularly for individuals with ASD who are less socially competent.
AN  - WOS:001336672600001
AU  - Ding,
AU  - X.
AU  - F.
AU  - Wu,
AU  - J.
AU  - L.
AU  - Li,
AU  - D.
AU  - Liu,
AU  - Z.
AU  - X.
DB  - November 2024.enl
DO  - 10.3389/fpsyt.2024.1436170
L1  - internal-pdf://3377561928/Ding-2024-The benefit of rhythm-based interven.pdf
PY  - 2024
SP  - 11
T2  - Frontiers in Psychiatry
TI  - The benefit of rhythm-based interventions for individuals with autism spectrum disorder: a systematic review and meta-analysis with random controlled trials
UR  - &lt;Go to ISI&gt;://WOS:001336672600001
UR  - https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1436170/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - This meta-analysis aimed to examine the effectiveness of interventions for youth that activate the social network for improving youth outcomes (e.g. psychological problems, child safety). A literature search yielded 37 studies with 35 independent samples (N = 712,269) of youth aged 0-26 years (M = 7.20), and 409 effect sizes. A three-level meta-analysis controlling for the dependency among effect sizes within studies showed no overall effect of interventions activating the social network (d = 0.11, p = .241). Yet, moderator analyses revealed positive effects for youth-initiated mentoring interventions (d = 0.46), youth deciding who to involve (d = 0.52), interventions that involve only one person (d = 0.56), European samples (d = 0.40), interventions targeting youth with mental health needs (d = 0.75), data retrieved through questionnaires (d = 0.10) and official records (d = 0.14), assessments completed by professionals (d = 0.34) or parents (d = 0.17), and outcomes that were corrected for pretest differences between conditions (d = 0.27). This meta-analysis demonstrates that social network activation matters for intervention effectiveness under specific conditions.
AN  - WOS:001169745000001
AU  - Koper,
AU  - N.
AU  - van
AU  - der
AU  - Heijden,
AU  - R.
AU  - M.
AU  - Donk,
AU  - S.
AU  - Kieu,
AU  - T.
AU  - Creemers,
AU  - H.
AU  - E.
AU  - van
AU  - Dam,
AU  - L.
AU  - Branje,
AU  - S.
AU  - Stams,
AU  - Gjjm
DB  - Mars 24.enl
DO  - 10.1080/10888691.2024.2317714
L1  - internal-pdf://0376489595/Koper-2024-The effectiveness of interventions.pdf
PY  - 2024
SP  - 25
T2  - Applied Developmental Science
TI  - The effectiveness of interventions for youth that activate the social network: a meta-analytic study
UR  - &lt;Go to ISI&gt;://WOS:001169745000001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/10888691.2024.2317714
ER  -
TY  - JOUR
AB  - Naturalistic Developmental Behavioral Interventions have been described as culturally responsive and family-friendly interventions, with research demonstrating improvements in children&#039;s development when receiving these services. Given the child-directed nature of Naturalistic Developmental Behavioral Interventions and the intervention&#039;s congruence with families&#039; daily routines, many studies have examined the impact of Naturalistic Developmental Behavioral Interventions on family and family member quality of life. Therefore, we conducted a systematic review and meta-analysis to explore the relationship between Naturalistic Developmental Behavioral Interventions and family quality of life. Results suggest that the receipt of Naturalistic Developmental Behavioral Intervention services neither improved nor worsened family and family member quality of life. For those involved in the provision of Naturalistic Developmental Behavioral Intervention services, there is an immediate need to convey to families that children&#039;s improvements will likely not translate into improvements in family quality of life (osf.io/3ua5f). Lay abstract Naturalistic Developmental Behavioral Interventions have been described as culturally responsive and family-friendly interventions, with research demonstrating improvements in children&#039;s development following the receipt of these interventions. Given the child-directed nature of Naturalistic Developmental Behavioral Interventions and the intervention&#039;s integration within families&#039; daily routines, many studies have examined the impact of Naturalistic Developmental Behavioral Interventions on family and family member quality of life. We conducted a systematic review and meta-analysis to explore the relationship between Naturalistic Developmental Behavioral Interventions and family quality of life. Results suggest that the provision of a Naturalistic Developmental Behavioral Intervention neither improved nor worsened family or family member quality of life. For those involved in delivering Naturalistic Developmental Behavioral Intervention services, there is an immediate need to convey to families that children&#039;s improvements will likely not translate into improvements in family quality of life.
AN  - WOS:001157062600001
AU  - Duncan,
AU  - A.
AU  - L.
AU  - Keene,
AU  - H.
AU  - Shepley,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1177/13623613241227516
L1  - internal-pdf://0163191344/duncan-et-al-2024-do-naturalistic-developmenta.pdf
PY  - 2024
SP  - 14
T2  - Autism
TI  - Do Naturalistic Developmental Behavioral Interventions improve family quality of life? A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001157062600001
ER  -
TY  - JOUR
AB  - INTRODUCTION: Children and adolescents, after natural and man-made disasters, often exhibit various psychological, emotional, and behavioral issues, showing a range of clinical symptoms related to post-traumatic stress disorder (PTSD) and depression. This review used a network meta-analysis (NMA) approach to compare and rank psychological interventions for PTSD and depression in children and adolescents after exposure to natural and man-made disasters. 

METHODS: Randomized studies of psychosocial interventions for PTSD and depression in children and adolescents exposed to natural and man-made disasters were identified. PTSD and depression symptoms at postintervention and 1-12 month follow-up are the outcomes. The standardized mean differences (SMDs) between pairs of interventions at postintervention and follow-up were pooled. Mean effect sizes with 95% credible intervals (CI) were calculated, and the ranking probabilities for all interventions were estimated using the surface under the cumulative ranking curve. Study quality was assessed with version 2 of the Cochrane risk-of-bias tool for randomized trials (RoB 2).

RESULTS: In total, 26 studies with 4331 participants were included in this NMA. Eye movement desensitization and reprocessing therapy (EMDR) (SMD = - 0.67; 95% CI - 1.17 to - 0.17), exposure therapy (ET) (SMD = - 0.66; 95% CI - 1.11 to - 0.22), and cognitive behavioral therapy (CBT) (SMD = - 0.62; 95% CI - 0.90 to - 0.34) were significantly more effective for PTSD at postintervention than inactive intervention. EMDR (SMD = - 0.72; 95% CI - 1.11 to - 0.33) and ET (SMD = - 0.62; 95% CI - 0.97 to - 0.27) were associated with a higher reduction in PTSD symptoms at follow-up than inactive intervention. EMDR (SMD = - 0.40; 95% CI - 0.78 to - 0.03) and play therapy (PT) (SMD = - 0.37; 95% CI - 0.62 to - 0.12) were significantly more effective for depression at postintervention than inactive intervention. For all psychological interventions in reducing depression symptoms at follow-up compared with inactive intervention, the differences were not significant. 

CONCLUSION: EMDR appears to be most effective in reducing PTSD and depression in children and adolescents exposed to natural and man-made disasters. In addition, ET and CBT are potentially effective in reducing PTSD symptoms at postintervention, while PT is beneficial in managing depression symptoms at the treatment endpoint.
AN  - 38918741
AU  - Xie,
AU  - Y.
AU  - Zhu,
AU  - X.
AU  - Wang,
AU  - L.
AU  - Wan,
AU  - Z.
AU  - Yang,
AU  - J.
AU  - Su,
AU  - C.
AU  - Duan,
AU  - S.
AU  - Xu,
AU  - C.
AU  - Kan,
AU  - B.
DB  - Juni 24.enl
DO  - /10.1186/s12888-024-05924-8
L1  - internal-pdf://1902210548/Xie-2024-A network meta-analysis of psychologi.pdf
PY  - 2024
SP  - 468
T2  - BMC Psychiatry
TI  - A network meta-analysis of psychological interventions for children and adolescents after natural and man-made disasters
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.1186%2fs12888-024-05924-8
UR  - https://bmcpsychiatry.biomedcentral.com/counter/pdf/10.1186/s12888-024-05924-8.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - BACKGROUND: In recent decades, many interventions targeting the occurrence (primary prevention) or the recurrence (secondary prevention) of child abuse and neglect have been tested. Findings have been synthesized in several meta-analyses and systematic reviews. However, the range of interventions addressed in these studies is very broad, and an integrative assessment of this large spectrum is lacking. 

OBJECTIVE: Focusing on high-income countries, we ask (i) what is known about the effectiveness of interventions to prevent or reduce child abuse and neglect and (ii) how robust this evidence is. 

METHODS: A systematic review of systematic reviews, called an umbrella review, was conducted. Ten databases on OvidSP and Web of Science were searched up until April 2023. Narrative synthesis was used to document the publications&#039; findings. 

RESULTS: 44 publications were included in the umbrella review. We did not find that any type of intervention had a clear, consistent, and robust track record of preventing or reducing the occurrence of child abuse and neglect. Rather, publications examining the effectiveness of interventions in all areas frequently reported non-existent, small or inconsistent effects. However, positive effects for particular interventions in specific settings did emerge. Research methodologies showed several and often severe problems. 

CONCLUSIONS: We suggest several measures to improve the quality of research and call on practitioners to be persistent in developing more effective interventions.
AN  - 38761720
AU  - Gautschi,
AU  - J.
AU  - Latsch,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.chiabu.2024.106845
L1  - internal-pdf://1815305521/1-s2.0-S0145213424002357-main.cleaned.pdf
PY  - 2024
SP  - 106845
T2  - Child Abuse &amp; Neglect
TI  - The effectiveness of interventions to prevent and reduce child maltreatment in high-income countries: An umbrella review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.chiabu.2024.106845
UR  - https://www.sciencedirect.com/science/article/pii/S0145213424002357?via%3Dihub
VL  - 153
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Depression and anxiety are major public health problems. This study evaluated the effects of internet-delivered transdiagnostic psychological treatments for individuals with depression, anxiety, or both. 

**DESIGN**: Systematic review with meta-analysis. 

**DATA SOURCES**: Medline (Ovid), Cochrane Library (Wiley), the Web of Science Core Collection (Clarivate), and PsycInfo (EBSCO) were searched on 24 May 2021, with an update on 6 February 2023.

 **ELIGIBILITY CRITERIA**: Randomised controlled trials of internet-delivered transdiagnostic psychological treatments, open to both participants with primary depression and participants with primary anxiety. This review concerned all treatment frameworks, both guided and unguided formats and all age groups. 

**DATA EXTRACTION AND SYNTHESIS**: In random-effects meta-analysis, we estimated pooled effects on depression symptoms and anxiety in terms of Hedges&#039; g with 95% CIs. Absolute and relative heterogeneity was quantified as the tau&lt;sup&gt;2&lt;/sup&gt; and I &lt;sup&gt;2&lt;/sup&gt;. 

**RESULTS**: We included 57 trials with 21 795 participants. Nine trials (16%) recruited exclusively from routine care, and three (5%) delivered treatment via video. For adults, large within-group reductions were seen in depression (g=0.90; 95% CI 0.81 to 0.99) and anxiety (g=0.87; 95% CI 0.78 to 0.96). Compared with rudimentary passive controls, the added effects were moderate (depression: g=0.52; 95% CI 0.42 to 0.63; anxiety: g=0.45; 95% CI 0.34 to 0.56) and larger in trials that required all participants to meet full diagnostic criteria for depression or an anxiety disorder. Compared with attention/engagement controls, the added effects were small (depression: g=0.30; 95% CI 0.07 to 0.53; anxiety: g=0.21; 95% CI 0.01 to 0.42). Heterogeneity was substantial, and the certainty of the evidence was very low. Two trials concerned adolescents and reported mixed results. One trial concerned older adults and reported promising results. 

**CONCLUSION**: Internet-delivered transdiagnostic treatments for depression and anxiety show small-to-moderate added effects, varying by control condition. Research is needed regarding routine care, the video format, children and adolescents and older adults. 

**PROSPERO REGISTRATION NUMBER**: CRD42021243172.
AN  - 38569713
AU  - Kolaas,
AU  - K.
AU  - Berman,
AU  - A.
AU  - H.
AU  - Hedman-Lagerlof,
AU  - E.
AU  - Lindsater,
AU  - E.
AU  - Hybelius,
AU  - J.
AU  - Axelsson,
AU  - E.
DB  - April 24.enl
DO  - /10.1136/bmjopen-2023-075796
L1  - internal-pdf://0799243800/Kolaas-2024-Internet-delivered transdiagnostic.pdf
PY  - 2024
SP  - e075796
T2  - Bmj Open
TI  - Internet-delivered transdiagnostic psychological treatments for individuals with depression, anxiety or both: a systematic review with meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1136%2fbmjopen-2023-075796
UR  - https://bmjopen.bmj.com/content/bmjopen/14/4/e075796.full.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Poor youth mental health is an area of global concern. Summer holiday programs may provide environments that support mental health when the structures and supports of school are not available. The aim of this review was to determine the effectiveness of summer holiday programs in improving the mental health, social-emotional well-being, and cognitive (non-academic) outcomes of children and adolescents. Studies of summer holiday programs for school-aged children (5-18 years) were included if they measured any mental, socio-emotional or cognitive (non-academic) outcome. Studies were excluded if they were published prior to 2000, targeted clinical populations or lasted less than five days. Six databases were searched (April 2023). Risk of bias was assessed using the PEDro tool. Study outcomes were grouped according to three main constructs: mental health (psychological well-being, anxiety, depression, distress, and self-perception including self-esteem, self-worth, self-concept, confidence, and competence); social-emotional well-being (behavior and social skills, e.g., communication, bullying, conflict resolution, empathy, and social skills); and cognitive function (memory, selective attention, and executive function). A fourth &quot;other&quot; group captured substance use, personality traits, character skills, and values. Effect sizes were calculated as the standardized mean difference between pre- and post-intervention scores. The synthesis involved a random-effects meta-analysis (presented in forest plots), where possible, with the remaining outcomes narratively synthesized. Twenty-six studies (n = 6812 participants) were included. The results of the meta-analysis suggested that summer programs showed a statistically non-significant trend toward reducing symptoms of anxiety and depression (k = 2 studies, SMD = -0.17, 95% CI -2.94, 2.60), psychological distress (k = 2 studies, SMD -0.46, 95% CI -1.71, 0.79), and no effect on self-esteem (k = 6 studies, SMD = 0.02, 95% CI -0.02, 0.06) or self-worth (k = 3 studies, SMD = 0.05, 95% CI 0.00, 0.11). Narrative syntheses indicated a pattern toward improvements in general mental health, self-perception, social-emotional outcomes, and cognition. Studies were generally small, with a high risk of bias. Summer holiday programs for children and adolescents show trends toward improving mental, social, emotional, and cognitive outcomes. Programs targeting disadvantaged children showed stronger patterns of improvement related to mental health and self-perception than programs targeting the general population. While effect sizes are small to negligible, they consistently indicate improvements. Summer programs present a promising avenue to promote mental health in children; however, further rigorously designed, clearly reported control-group studies are required to more fully understand their effects.
AN  - 39201822
AU  - Eglitis,
AU  - E.
AU  - Simpson,
AU  - C.
AU  - Singh,
AU  - B.
AU  - Olds,
AU  - T.
AU  - Machell,
AU  - A.
AU  - Virgara,
AU  - R.
AU  - Richardson,
AU  - M.
AU  - Brannelly,
AU  - K.
AU  - Grant,
AU  - A.
AU  - Gray,
AU  - J.
AU  - Wilkinson,
AU  - T.
AU  - Rix,
AU  - Z.
AU  - Maher,
AU  - C.
DB  - September 2024.enl
DO  - /10.3390/children11080887
L1  - internal-pdf://3865665164/Eglitis-2024-Effect of Summer Holiday Programs.pdf
PY  - 2024
SP  - 23
T2  - Children
TI  - Effect of Summer Holiday Programs on Children&#039;s Mental Health and Well-Being: Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3390%2fchildren11080887
UR  - https://mdpi-res.com/d_attachment/children/children-11-00887/article_deploy/children-11-00887-v2.pdf?version=1721818500
VL  - 11
ER  -
TY  - JOUR
AB  - Despite the widespread use of acupuncture, its effectiveness and safety in treating Tourette syndrome (TS) remain controversial. Our research seeks to further evaluate the safety and effectiveness of acupuncture as a replacement therapy approach for children with TS. We conducted a comprehensive search for studies published from their inception to October 2023. The statistical analysis and subgroup analysis were conducted by software. Conduct a meta-analysis on the extracted data using the appropriate effect models. The meta-analysis was conducted on 26 studies consisting 1862 pediatric patients, which were selected from 976 identified articles. Acupuncture group demonstrated a significantly lower risk with a risk ratio (RR) of 0.29 (95% confidence interval [CI] = 0.19, 0.44, P &lt; .0001), with only 5% of participants experiencing adverse reactions. Acupuncture treatment resulted in an 18% improvement in total effectiveness rates (RR = 1.18, 95% CI = [1.12, 1.25], P &lt; .00001). The pooled data demonstrated that acupuncture therapy had a significant advantage in reducing the total score with the weighted mean difference (WMD) -4.92 (95% CI = [-6.38, -3.45], P &lt; .00001) of the Yale Global Tic Severity Scale (YGTSS), the motor tic scores (WMD = -2.24, 95% CI = [-3.14, -1.35], P &lt; .00001), the vocal tic scores (WMD: -2.34, 95% CI = [-3.31, -1.37], P &lt; .00001), and the Traditional Chinese Medicine Syndrome Scores (TCMSS) (WMD: -2.47, 95% CI = [-2.87, -2.07], P &lt; .0001). This meta-analysis reveals that acupuncture is more effective than most existing treatments in mitigating the symptoms of motor and vocal tics in children with TS, while also reducing the incidence of adverse reactions.
AN  - 39345099
AU  - Lai,
AU  - S.
AU  - Wan,
AU  - H.
AU  - Deng,
AU  - F.
AU  - Li,
AU  - Y.
AU  - An,
AU  - Y.
AU  - Peng,
AU  - J.
AU  - Yang,
AU  - X.
AU  - N.
DB  - September 2024.enl
DO  - /10.1177/00099228241283279
L1  - internal-pdf://1697928751/lai-et-al-2024-efficacy-and-safety-of-acupunct.pdf
PY  - 2024
SP  - 99228241283279
T2  - Clinical Pediatrics
TI  - Efficacy and Safety of Acupuncture for Tourette Syndrome in Children: A Meta-Analysis and Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1177%2f00099228241283279
ER  -
TY  - JOUR
AB  - Lisdexamfetamine dimesylate, a prodrug stimulant, appears to effectively treat AttentionDeficit/Hyperactivity Disorder (ADHD) in children and adults. However, an analysis of the treatment effects of the two subscales (inattentiveness and hyperactivity) within the ADHD Rating Scale-IV (ADHD-RS-IV) has not yet been done to determine if clinical significance may be attributed to either one. Nor has there been a meta-analysis of the individual doses of lisdexamfetamine dimesylate. The current meta-analysis utilizes MEDLINE, Embase, Cochrane, PubMed, and clinicaltrials.gov to identify peer-reviewed studies. Selected studies were eligible if they met the following criteria: English language, randomized-controlled trials, and utilized the ADHD-RS-IV scale to assess the efficacy of lisdexamfetamine on treating ADHD in either children or adults. The primary studies utilized were published between January 2007 and April 2024. Many of these studies calculate effect sizes based on several dosages pooled together rather than by individual dosages. We conducted a random-effects meta-analysis to estimate the effect sizes for these pooled dosages on the full ADHD-RS-IV scale and its subscales, as well as to calculate effect sizes on the same scales based on the individual dosages. Our main outcome measures are the ADHD-RS-IV scale and its subscales in individual doses and pooled results in both children and adults. Adverse events during treatment were also analyzed based on stratified dosages. Eleven publications met our inclusion criteria. The analyses indicate that compared to placebo, lisdexamfetamine effectively alleviates the symptoms outlined by the ADHD-RSIV. Moreover, there are no differences in the individual subscales or in the safety profile. Lisdexamfetamine demonstrates efficacy in treating the symptoms of ADHD, but we report that differing dosages did not yield significant differences in ADHD symptom management.
AN  - WOS:001306263300005
AU  - Rutledge-Jukes,
AU  - H.
AU  - Jonnalagadda,
AU  - P.
AU  - McIntosh,
AU  - A.
AU  - P.
AU  - Krstovski,
AU  - S.
AU  - Andriani,
AU  - N.
AU  - Smith,
AU  - I.
AU  - R.
AU  - Prendergast,
AU  - L.
AU  - Lynch,
AU  - J.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.7759/cureus.68324
L1  - internal-pdf://1621951522/Rutledge-Jukes-2024-Lisdexamfetamine&#039;s Efficac.pdf
PY  - 2024
SP  - 15
T2  - Cureus Journal of Medical Science
TI  - Lisdexamfetamine&#039;s Efficacy in Treating Attention Deficit Hyperactivity Disorder (ADHD): A Meta-Analysis and Review
UR  - &lt;Go to ISI&gt;://WOS:001306263300005
UR  - https://assets.cureus.com/uploads/review_article/pdf/256810/20240930-1579991-el6y8k.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - BACKGROUND: The ability of socially assistive robots (SARs) to treat dementia and Alzheimer&#039;s disease has been verified. Currently, to increase the range of their application, there is an increasing amount of interest in using SARs to relieve pain and negative emotions among children in routine medical settings. However, there is little consensus regarding the use of these robots.

OBJECTIVE: This study aimed to evaluate the effect of SARs on pain and negative affectivity among children undergoing invasive needle-based procedures.

DESIGN: This study was a systematic review and meta-analysis of randomized controlled trials that was conducted in accordance with the Cochrane Handbook guidelines. 

METHODS: The PubMed, CINAHL, Web of Science, Cochrane Library, Embase, CNKI, and WanFang databases were searched from inception to January 2024 to identify relevant randomized controlled trials (RCTs). We used the Cochrane Risk of Bias tool 2.0 (RoB2.0) to assess the risk of bias among the included studies, and we used RevMan 5.4 software to conduct the meta-analysis. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework was used to assess the quality of the evidence. 

RESULTS: Ten RCTs involving 815 pediatric subjects were selected for this review and reported outcomes related to pain and emotions during IV placement, port needle insertion, flu vaccination, blood sampling, and dental treatment. Children undergoing needle-related procedures with SARs reported less anxiety (SMD= -0.36; 95% CI= -0.64, -0.09) and fewer distressed avoidance behaviors (SMD= -0.67; 95% CI= -1.04, -0.30) than did those receiving typical care. There were nonsignificant differences between these groups in terms of in pain (SMD = -0.02; 95% CI = - 0.81, 0.78) and fear (SMD = 0.38; 95% CI= -0.06, 0.82). The results of exploratory subgroup analyses revealed no statistically significant differences based on the intervention type of robots or anesthetic use. 

CONCLUSIONS: The use of SARs is a promising intervention method for alleviating anxiety and distress among children undergoing needle-related procedures. However, additional high-quality randomized controlled trials are needed to further validate these conclusions. 

TRIAL REGISTRATION: The protocol of this study has been registered in the database PROSPERO (registration ID: CRD42023413279).
AN  - 39390439
AU  - Pan,
AU  - X.
AU  - Y.
AU  - Bi,
AU  - X.
AU  - Y.
AU  - Nong,
AU  - Y.
AU  - N.
AU  - Ye,
AU  - X.
AU  - C.
AU  - Yan,
AU  - Y.
AU  - Shang,
AU  - J.
AU  - Zhou,
AU  - Y.
AU  - M.
AU  - Yao,
AU  - Y.
AU  - Z.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1186/s12887-024-05116-z
L1  - internal-pdf://0570883747/Pan-2024-The efficacy of socially assistive ro.pdf
PY  - 2024
SP  - 643
T2  - Bmc Pediatrics
TI  - The efficacy of socially assistive robots in improving children&#039;s pain and negative affectivity during needle-based invasive treatment: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1186%2fs12887-024-05116-z
UR  - https://bmcpediatr.biomedcentral.com/counter/pdf/10.1186/s12887-024-05116-z.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - **Background and Objectives**: Ecopipam is a selective antagonist of the dopamine D1 receptor, and its efficacy and safety have recently been explored in several clinical trials involving patients with Tourette syndrome (TS). The objectives of this systematic review were to determine the pooled estimate for efficacy [in terms of reduction in tic Yale Global Tic Severity Scale (YGTSS) scores] and safety of oral ecopipam in subjects with TS. **Methods**:  All clinical trials that explored the efficacy and/or safety of ecopipam in patients with TS were included to determine the pooled estimate for change in YGTSS, Clinical Global Impression (CGI)-TS, and the severity of comorbid attention-deficit hyperactive disorder (ADHD), obsessive compulsion disorder (OCD), and depressive symptoms, as well as the nature and frequency of adverse effects. Case-series, retrospective studies, and case reports were excluded. Databases, such as PUBMED, EMBASE, Cochrane Central Register of Controlled Trials, and SCOPUS were searched to identify these trials using suitable combination of MESH terms/keywords on 15 June 2024. ROB 2.0 and ROBINS-I tool were used to assess the risk of bias in included randomized-controlled trials (RCTs) and non-randomized intervention studies, respectively, and the GRADE system to determine the certainty of the collated evidence. **Results**:  A total of 96 records were identified in the database search and 31 records were screened after removing duplicates. After excluding 23 irrelevant records, the full-text review included 8 records. Finally, six publications from three completed clinical trials (two RCTs, with one having an open-label extension) and one ongoing clinical trial were included. A total of 251 participants were included. The pooled estimate for mean change in YGTSS-TTS from baseline to the completion of the randomization period was statistically better in the ecopipam group compared with the placebo group [mean difference: - 3.0, 95% (confidence interval (CI) - 4.2 to - 1.9, I-2 = 55%, p &lt; 0.0001]. The ecopipam group also fared statistically better in terms of YGTSS-motor tic score, phonic tic score, as well as CGI-TS-S (p &lt; 0.0001). Changes in depressive and obsessive-compulsive symptoms were comparable in both groups, as well as the incidence of adverse effects. **Conclusions**: Ecopipam is effective in reducing the severity of tics in subjects with TS and has a good safety profile. However, only a limited number of studies were included in the review, with some having small sample sizes and short duration of follow-up.
AN  - WOS:001385773300001
AU  - Panda,
AU  - P.
AU  - K.
AU  - Panda,
AU  - P.
AU  - Dawman,
AU  - L.
AU  - Mishra,
AU  - A.
AU  - S.
AU  - Kumar,
AU  - V.
AU  - Sharawat,
AU  - I.
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1007/s40263-024-01140-w
L1  - internal-pdf://1697462019/Panda-2024-Safety and Efficacy of Ecopipam in.pdf
PY  - 2024
SP  - 16
T2  - Cns Drugs
TI  - Safety and Efficacy of Ecopipam in Patients with Tourette Syndrome: A Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001385773300001
UR  - https://link.springer.com/article/10.1007/s40263-024-01140-w
UR  - https://link.springer.com/content/pdf/10.1007/s40263-024-01140-w.pdf
ER  -
TY  - JOUR
AB  - Conduct problems are a range of disruptive behaviours in childhood that are associated with long-term adverse outcomes in adolescence and adulthood, including antisocial behaviour, substance misuse, and poor academic achievement. Children with conduct problems can vary according to age of onset, comorbidities, and environmental factors, and certain groups of children may have different treatment outcomes. It is therefore important to assess the extent to which personalised interventions for pre-specified groups of children with conduct problems may affect outcomes. We searched 13 databases and 2 trials registers up to February 2022. Randomized controlled trials, in any setting, of children (2-12 years old) with conduct problems and within a pre-specified subgroup, comparing a personalised intervention with a non-personalised intervention, waitlist control or treatment as usual were included. Personalised intervention may improve child conduct problems or disruptive behaviour measured using the Eyberg Child Behavior Inventory (ECBI) Problem subscale in the short term but may have little to no effect on improving child conduct problems or disruptive behaviour measured by the ECBI Intensity subscale or the Externalising subscale of the Child Behaviour Checklist in the short term. The certainty of evidence for all outcomes was graded as very low. In conclusion, there is limited evidence for the effectiveness of personalised interventions for subgroups of children with conduct problems.
AN  - WOS:001159357000001
AU  - Skinner,
AU  - G.
AU  - C.
AU  - M.
AU  - Lane,
AU  - C.
AU  - Hogg,
AU  - E.
AU  - Karwatowska,
AU  - L.
AU  - A.
AU  - French,
AU  - L.
AU  - Ranieri,
AU  - V.
AU  - F.
AU  - Jesnick,
AU  - L.
AU  - G.
AU  - D.
AU  - Roberts,
AU  - C.
AU  - Scott,
AU  - S.
AU  - Senior,
AU  - R.
AU  - Kennedy,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1080/14789949.2024.2314642
L1  - internal-pdf://1635604406/Personalised interventions for subgroups of ch.pdf
PY  - 2024
SP  - 21
T2  - Journal of Forensic Psychiatry &amp; Psychology
TI  - Personalised interventions for subgroups of children with conduct problems: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:001159357000001
ER  -
TY  - JOUR
AB  - In order to provide more individualized support, it is imperative to further understand the effectiveness of different types of psychotherapy on the clinical areas of need common in autistic youth (Wood et al. in Behav Ther 46:83-95, 2015). Randomized controlled trials of psychotherapy for autistic youth were included if published in English, included random assignment to treatment or control group, required a previous diagnosis of autism, had a mean age of 6-17 years, and provided outcome measure data from both intervention and control groups. A total of 133 measures were coded across 29 studies and included 1464 participants with a mean age of 10.39 years (1.89). A small mean effect size (0.38,95% CI [0.26, 0.47]) was found overall, with the largest effects for cognitive behavioral therapies on autism-related clinical needs (0.81) and overall mental health (0.78). The results show the significant impact of psychotherapy interventions for autistic youth. Additional research should further assess the details of the most effective psychotherapies for each area of clinical need.
AN  - WOS:001197491000001
AU  - Rosenau,
AU  - K.
AU  - A.
AU  - Kim,
AU  - J.
AU  - Cho,
AU  - A.
AU  - C.
AU  - B.
AU  - Seltzer,
AU  - M.
AU  - Ugueto,
AU  - A.
AU  - M.
AU  - Weisz,
AU  - J.
AU  - R.
AU  - Wood,
AU  - J.
AU  - J.
DB  - April 24.enl
DO  - 10.1007/s10578-024-01686-2
L1  - internal-pdf://3097086219/Rosenau-2024-Meta-analysis of Psychotherapy fo.pdf
PY  - 2024
SP  - 12
T2  - Child Psychiatry &amp; Human Development
TI  - Meta-analysis of Psychotherapy for Autistic Youth
UR  - &lt;Go to ISI&gt;://WOS:001197491000001
UR  - https://link.springer.com/content/pdf/10.1007/s10578-024-01686-2.pdf
ER  -
TY  - JOUR
AB  - Parenting programs aim to motivate change in parents&#039; behaviors, perceptions, and knowledge to promote desirable changes in children&#039;s adjustment and behavior. Parenting programs are typically delivered in a group-based or individual format, and it is unknown which format most effectively supports parents. On the one hand, group-based programs may be more effective since they provide access to peer-based support. On the other hand, individual programs may be more successful since they offer a tailored approach. Therefore, this meta-analysis investigated which delivery format is most effective in optimizing child behavior management (i.e., positive reinforcement and nonviolent discipline), parenting stress, and parental depressive symptoms. Studies were selected from the systematic review by Backhaus et al. (2023). Our sample included evaluations of 121 group-based and 41 individual programs based on social learning theory principles. Robust variance estimation indicated that parents&#039; child behavior management and parenting stress improved in both delivery formats. In contrast, parental depressive symptoms improved only in group-based programs. Our findings suggest that whether parents benefit more from a group-based or individual program in part depends on the outcome examined. Therefore, it is important for clinicians to understand parents&#039; goals to effectively guide them toward the most appropriate parenting program delivery format. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2025-37774-001
AU  - Mathijs,
AU  - Louise
AU  - Van
AU  - Petegem,
AU  - Stijn
AU  - Melendez-Torres,
AU  - G.
AU  - Backhaus,
AU  - Sophia
AU  - Gardner,
AU  - Frances
AU  - Leijten,
AU  - Patty
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1037/fam0001273
L1  - internal-pdf://1746599415/2025-37774-001.cleaned.pdf
PY  - 2024
SP  - No Pagination Specified
T2  - Journal of Family Psychology
TI  - Group-based versus individual parenting programs: A meta-analysis of effects on parents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.1037%2ffam0001273
ER  -
TY  - JOUR
AB  - BACKGROUND: Synthesized evidence regarding the effectiveness of non-invasive neuromodulation treatment for adolescents remains scarce. This study aimed to perform the first meta-analysis of the impact of neuromodulation treatment on depressive symptoms in adolescents. 

METHODS: According to the PRISMA guidelines, a comprehensive review covering databases in English and Chinese from their inception to November 30, 2023, was conducted. Data were pooled to compute the standardized mean difference (SMD) and risk ratio (RR), along with their respective 95 % confidence intervals (CI). 

RESULTS: A total of 27 studies involving 2075 participants were included and examined. Noninvasive neuromodulation treatment demonstrated significant positive effects on depression symptoms compared with controlled conditions (Hamilton Depression Scale (HAMD) 17: SMD = 3.503, 95 % CI = 2.404-4.602, p &lt; 0.001; HAMD 24: SMD = 3.375, 95 % CI = 2.437-4.314, p &lt; 0.001). High heterogeneity was observed (I&lt;sup&gt;2&lt;/sup&gt; = 95.2 % and 97.2 %, p &lt; 0.01), along with a substantial risk of publication bias (p &lt; 0.05). In terms of the treatment response, the RR reached 1.39 (95 % CI = 1.29-1.50, p &lt; 0.001), with low heterogeneity (I&lt;sup&gt;2&lt;/sup&gt; = 35 %, p = 0.07). 

CONCLUSIONS: Noninvasive neuromodulation treatment significant alleviated depressive symptoms in adolescents. Future research should prioritize conducting high-quality clinical trials to determine the suitable selection of adolescent patients for this treatment. In addition, these trials can help guide precision medicine approaches for stimulation protocols.
AN  - 39719809
AU  - Tang,
AU  - M.
AU  - Zheng,
AU  - Y.
AU  - Zhang,
AU  - X.
AU  - Fan,
AU  - X.
DB  - Desember 2024.enl
DO  - /10.1016/j.psychres.2024.116329
L1  - internal-pdf://1230109999/009e5683-3055-4286-89a1-853f497afa39.pdf
PY  - 2024
SP  - 116329
T2  - Psychiatry Research
TI  - Non-invasive neuromodulation treatment for depression in adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.psychres.2024.116329
UR  - https://www.sciencedirect.com/science/article/pii/S0165178124006140?via%3Dihub
VL  - 344
ER  -
TY  - JOUR
AB  - This systematic review and meta-analyses aim to synthesise evidence about behavioural interventions to address dysregulated sleeping and cry/fuss behaviour in infants aged up to 12 months and the effects on infant behaviour and maternal mental health. A systematic literature search of English-language publications was performed in November 2020 and updated in May 2023 using Medline, Embase, PsychInfo and Cinahl Plus. Twenty-two papers reporting twenty studies met inclusion criteria of these sixteen papers reported both maternal and infant outcomes. Although, there is heterogeneity of the investigations, their results are broadly consistent. Parents who attended a behavioural intervention program for unsettled behaviours in infants reported improvement of their mental health and parenting confidence, and unsettled infant behaviours were improved including a reduction of night waking and cry/fuss behaviour. This review and meta-analyse provides evidence that behavioural interventions show a mild to moderate improvement in unsettled infant behaviour and maternal mental health.
AN  - WOS:001374965300001
AU  - Stanzel,
AU  - K.
AU  - Honda,
AU  - T.
AU  - Tran,
AU  - T.
AU  - Fisher,
AU  - J.
DB  - Desember 2024.enl
DO  - 10.1002/icd.2554
L1  - internal-pdf://3379230672/Stanzel-2024-Behavioural Interventions for Pro.pdf
PY  - 2024
SP  - 24
T2  - Infant and Child Development
TI  - Behavioural Interventions for Problematic Infant Sleeping and Cry/Fuss Behaviour: A Systematic Review and Meta-Analyses
UR  - &lt;Go to ISI&gt;://WOS:001374965300001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/icd.2554?download=true
ER  -
TY  - JOUR
AB  - **Objectives:** Disruptive mood dysregulation disorder (DMDD) is a relatively new diagnosis that comprises severe, nonepisodic irritability and recurrent outbursts of emotional instability in adolescents. This meta-analysis examined the efficacy of the available pharmacological and nonpharmacological interventions for DMDD. 

**Methods:** Literature searches were conducted in July 2023. To determine relevant articles, 330 abstracts were reviewed, and 39 articles were identified for full review. A random-effects model was used for the meta-analysis, and a subgroup analysis was performed to assess the effects of study design and intervention type. 

**Results:** Eleven studies were reviewed, including six pharmacological and five nonpharmacological. Despite high heterogeneity in effects (I&lt;sup&gt;2&lt;/sup&gt; = 85%), we showed statistically significant improvements in irritability symptoms following intervention. We showed statistically significant enhancements in symptoms of irritability following the intervention. The subgroup analysis revealed that, compared with randomized controlled trials (RCTs), open trials showed significant improvements in irritability. In addition, drug intervention significantly improved irritability compared to nondrug interventions. Atomoxetine (ATX), optimized stimulants, and stimulants combined with other drugs and behavioral therapy effectively improved irritability. 

**Conclusions:** With research indicating potential benefits for irritability from a combination of pharmacological interventions and therapy, including ATX, stimulants in conjunction with antipsychotic or antidepressant medications, and cognitive-behavioral techniques such as Dialectical Behavior Therapy for Children. Future large-scale RCTs are essential to further explore and refine these treatment approaches, especially focusing on the efficacy of combining pharmacological with effective nonpharmacological to improve irritability and overall outcomes in this population.
AN  - 38683583
AU  - Zhang,
AU  - Y.
AU  - Zhang,
AU  - W.
AU  - Yu,
AU  - E.
DB  - April 24.enl
DO  - /10.1089/cap.2024.0013
L1  - internal-pdf://1151320660/zhang-et-al-2024-systematic-review-and-meta-an.pdf
PY  - 2024
SP  - 29
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Systematic Review and Meta-Analysis: Pharmacological and Nonpharmacological Interventions for Disruptive Mood Dysregulation Disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1089%2fcap.2024.0013
VL  - 29
ER  -
TY  - JOUR
AB  - This meta-analysis aims to systematically evaluate if different physical activities (PA) improve the social communication impairments (SCI) seen in children with autism spectrum disorder (ASD). For this meta-analysis, five databases (Web of Science, PubMed and Cochrane Library database in English, and CNKI and Wanfang Data Knowledge Service Platform in Chinese) were searched from database inception to September 11, 2024. The eligibility criteria included (1) study population comprised children with ASD, with no gender restriction; (2) experimental group consisted of a PA intervention; (3) control group consisted of nonPA interventions or routine activities; (4) outcomes were assessed using validated SCI scales (e.g., social cognition, social motivation, and/or social awareness); and (5) study design involved a randomized parallel group design. The quality of the evidence for each study was assessed using the Cochrane Risk of Bias tool. From a pool of 2714 potentially relevant articles, 17 were eligible for inclusion in this review. The results of overall response of PA intervention to SCI illustrated a Medium degree of statistical heterogeneity between studies (I&lt;sup&gt;2&lt;/sup&gt; = 53.3 %, p &lt; 0.01); the effect size of PA intervention on SCI (expressed as standardized mean difference) was -0.34 (95 % CI: -0.57, -0.11), which was statistically significant. SCI of autistic children could be potentially improved by PA interventions, though further research is needed to clarify if benefits achieve clinical significance in addition to statistical significance. Proper design of PA interventions (45-90 min per session, more than 3 times per week and for 8-12 weeks) may enhance their effectiveness in treating SCI in children with ASD.
AN  - 39640832
AU  - Qi,
AU  - K.
AU  - Wang,
AU  - X.
AU  - Xu,
AU  - Q.
AU  - Hu,
AU  - B.
AU  - Wang,
AU  - Z.
AU  - Bialas,
AU  - M.
DB  - Desember 2024.enl
DO  - /10.1016/j.heliyon.2024.e39053
L1  - internal-pdf://3022125070/Qi-2024-Effect of physical activity on social.pdf
PY  - 2024
SP  - e39053
T2  - Heliyon
TI  - Effect of physical activity on social communication impairments in children with autism spectrum disorder: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.1016%2fj.heliyon.2024.e39053
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11620107/pdf/main.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - Background: Extensive research has documented the positive impacts of physical activity on children and adolescents with Autism Spectrum Disorders (ASD). However, the specific benefits of various sports on the social functioning of children with ASD remain ambiguous. This study aims to employ a network meta-analysis to investigate the effects of different sports on the social functioning of children and adolescents with ASD and to establish a ranking of their effectiveness. Methods: This study conducted a comprehensive online search across Web of Science, PubMed, Cochrane, and Embase databases for randomized controlled trials and quasi-experimental studies focusing on social functioning outcomes. Data were synthesized using a Bayesian framework. Results: Sixteen relevant studies encompassing 560 participants were included. According to Cohen&#039;s classification, mini-basketball (SMD = 0.84, 95% CI: 0.46, 1.20), SPARK (SMD = 0.88, 95% CI: 0.06, 1.70), and Karate (SMD = 1.10, 95% CI: 0.27, 2.00) demonstrated high effect sizes, with Karate identified as the most effective intervention. Conversely, Combined Exercise and Nei Yang Gong interventions exhibited the least significant effects, falling below small effect sizes. Conclusion: Physical activity interventions have been shown to enhance social functioning in children and adolescents with ASD to varying extents, with Karate emerging as the most efficacious.
AN  - WOS:001299610400001
AU  - Hou,
AU  - Y.
AU  - Q.
AU  - Song,
AU  - Z.
AU  - Deng,
AU  - J.
AU  - Q.
AU  - Song,
AU  - X.
AU  - Q.
DB  - September 2024.enl
DO  - 10.3389/fpubh.2024.1399642
L1  - internal-pdf://2151436965/Hou-2024-The impact of exercise intervention o.pdf
PY  - 2024
SP  - 10
T2  - Frontiers in Public Health
TI  - The impact of exercise intervention on social interaction in children with autism: a network meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001299610400001
UR  - https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2024.1399642/pdf
VL  - 12
ER  -
TY  - JOUR
AB  - Previous reviews have synthesized the impacts of universal school-based social emotional learning (SEL) programs. However, they have yet to attempt a meta-analytic approach with rigorous inclusion criteria to identify the key SEL components and explore what make these programs work. This study aims to fill that gap by examining the impacts of SEL programs and exploring the moderating effects of methodological characteristics, implementation features, and program components on SEL effectiveness. The final sample consisted of 12 high-quality SEL programs, 59 studies, and 83,233 participants, with an overall effect size of 0.15. Meta-regression results indicated that these SEL programs could significantly improve youth social emotional skills, reinforce affect and attitudes, promote academic performance, increase prosocial behaviors, and reduce antisocial behaviors. Training teachers&#039; social emotional skills and reducing cognitive elements in SEL curricula were found to be effective components of SEL programs, whereas pedagogical activities, climate support, and family engagement were not. Large-scale studies of SEL programs tended to generate smaller effect sizes, and those with low program dosages were found to be less effective than those approaching the recommended dosage. Policy and practical implications on how to scale SEL programs are discussed.
AN  - 38280178
AU  - Shi,
AU  - J.
AU  - Cheung,
AU  - A.
AU  - C.
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10964-024-01942-7
L1  - internal-pdf://0259491981/Shi-2024-Effective Components of Social Emotio.pdf
PY  - 2024
SP  - 27
T2  - Journal of Youth &amp; Adolescence
TI  - Effective Components of Social Emotional Learning Programs: A Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38280178
UR  - https://link.springer.com/article/10.1007/s10964-024-01942-7
UR  - https://link.springer.com/content/pdf/10.1007/s10964-024-01942-7.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - This review compared the efficacy of personalized psychological interventions to standardized interventions for adolescents. We conducted a scoping review and meta-analysis of randomized controlled trials that compared personalized interventions with standardized interventions in adolescents. Data was analyzed using Bayesian multilevel random effects meta-analysis. Eligible studies were identified through five databases: Scopus, PsycINFO, MEDLINE, Web of Science, and EMBASE. Moderation analysis was conducted to explain potential sources of effect size heterogeneity. Eight studies across 13 articles (participant N = 2,490) met inclusion criteria for the review with seven studies across 10 articles (N = 1,347) providing sufficient data for inclusion in the meta-analysis. A small but significant effect size favoring personalized interventions was found (d = 0.21, 95% CrI [0.02, 0.39]), indicating that personalized interventions are associated with superior treatment outcomes compared to standardized interventions. Moderate between-study heterogeneity was found (I&lt;sup&gt;2&lt;/sup&gt; = 53.3%). There was no evidence of publication bias. The review also found significant variation in methods of treatment personalization. This review provides evidence that personalization of adolescent psychological interventions is an effective way to improve treatment outcomes. Given the large number of adolescents worldwide who will experience some sort of mental health problem, personalization could have a significantly large impact on global mental health outcomes. <b>Systematic review registration</b>: https://doi.org/10.17605/OSF.IO/XRNCG.
AN  - 39309145
AU  - Li,
AU  - W.
AU  - Gleeson,
AU  - J.
AU  - Fraser,
AU  - M.
AU  - I.
AU  - Ciarrochi,
AU  - J.
AU  - Hofmann,
AU  - S.
AU  - G.
AU  - Hayes,
AU  - S.
AU  - C.
AU  - Sahdra,
AU  - B.
DB  - September 2024.enl
DO  - /10.3389/fpsyg.2024.1470817
L1  - internal-pdf://3738260055/Li-2024-The efficacy of personalized psycholog.pdf
PY  - 2024
SP  - 1470817
T2  - Frontiers in Psychology
TI  - The efficacy of personalized psychological interventions in adolescents: a scoping review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffpsyg.2024.1470817
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413809/pdf/fpsyg-15-1470817.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Up to 30% of subjects with obsessive compulsive disorder (OCD) also have a lifetime tic disorder. Several metaanalyses of pharmaceutical or psychotherapeutic interventions for the management of OCD have been published, but none specifically on patients with OCD comorbid with tics. The literature regarding pharmacological treatments of patients with this condition is mainly focused on studies of OCD. After a search of the Cochrane, EMBASE, PubMed, PsychINFO and Science Direct databases, we performed a proportion meta-analysis of the percentage of patients whose condition improved and a paired meta-analysis of the change in the OCD score (YBOCS). Twelve case reports were retained for qualitative analysis and 14 articles for meta-analysis. Case reports showed better efficacy of combined antidepressant-antipsychotic treatment for OCD comorbid with tic disorder. The meta-analysis showed an improvement in 29% [18-42] of patients with antidepressants. Although there was no significant difference with placebo add-on, in antidepressant-resistant OCD patients, adding an antipsychotic to the antidepressant regimen led to an increase in the number of patients who improved (67% [45-86] vs 7% [0-35]) and seemed to show a decrease in the Y-BOCS score (-10.06 [-20.38; 0.26] vs (-3.61 [-9.08; 13.85]). Our study provides new evidence on the pharmacological treatment of OCD comorbid with tics. In some patients, the condition is improved by a first-line antidepressant. In case of non-response or insufficient efficacy of antidepressants, add-on treatment with certain antipsychotics can be implemented.
AN  - WOS:001333312200001
AU  - Jalenques,
AU  - I.
AU  - Asatryan,
AU  - V.
AU  - Tauveron-Jalenques,
AU  - U.
AU  - Pereira,
AU  - B.
AU  - Rondepierre,
AU  - F.
DB  - November 2024.enl
DO  - 10.1016/j.jpsychires.2024.09.048
L1  - internal-pdf://3697703147/1-s2.0-S0022395624005703-main.pdf
N1  - Brynhildur Axelsdottir (2024-12-02 18:12:55)(Screen): Tror det er voksne - men må sjekkes.;
PY  - 2024
SP  - 24-32
T2  - Journal of Psychiatric Research
TI  - Efficacy of pharmacological treatment in OCD comorbid with tic disorder: Systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001333312200001
UR  - https://www.sciencedirect.com/science/article/pii/S0022395624005703?via%3Dihub
VL  - 180
ER  -
TY  - JOUR
AB  - Autistic children and young people (CYP) experience mental health difficulties but face many barriers to accessing and benefiting from mental health care. There is a need to explore strategies in mental health care for autistic CYP to guide clinical practice and future research and support their mental health needs. Our aim was to identify strategies used to improve mental health care for autistic CYP and examine evidence on their acceptability, feasibility, and effectiveness. A systematic review and meta-analysis were carried out. All study designs reporting acceptability/feasibility outcomes and empirical quantitative studies reporting effectiveness outcomes for strategies tested within mental health care were eligible. We conducted a narrative synthesis and separate meta-analyses by informant (self, parent, and clinician). Fifty-seven papers were included, with most investigating cognitive behavioral therapy (CBT)-based interventions for anxiety and several exploring service-level strategies, such as autism screening tools, clinician training, and adaptations regarding organization of services. Most papers described caregiver involvement in therapy and reported adaptations to communication and intervention content; a few reported environmental adjustments. In the meta-analyses, parent- and clinician-reported outcomes, but not self-reported outcomes, showed with moderate certainty that CBT for anxiety was an effective treatment compared to any comparison condition in reducing anxiety symptoms in autistic individuals. The certainty of evidence for effectiveness, synthesized narratively, ranged from low to moderate. Evidence for feasibility and acceptability tended to be positive. Many identified strategies are simple, reasonable adjustments that can be implemented in services to enhance mental health care for autistic individuals. Notable research gaps persist, however.
AN  - 38757186
AU  - Pemovska,
AU  - T.
AU  - Loizou,
AU  - S.
AU  - Appleton,
AU  - R.
AU  - Spain,
AU  - D.
AU  - Stefanidou,
AU  - T.
AU  - Kular,
AU  - A.
AU  - Cooper,
AU  - R.
AU  - Greenburgh,
AU  - A.
AU  - Griffiths,
AU  - J.
AU  - Barnett,
AU  - P.
AU  - Foye,
AU  - U.
AU  - Baldwin,
AU  - H.
AU  - Minchin,
AU  - M.
AU  - Brady,
AU  - G.
AU  - Saunders,
AU  - K.
AU  - R.
AU  - K.
AU  - Ahmed,
AU  - N.
AU  - Jackson,
AU  - R.
AU  - Olive,
AU  - R.
AU  - R.
AU  - Parker,
AU  - J.
AU  - Timmerman,
AU  - A.
AU  - Sapiets,
AU  - S.
AU  - Driskell,
AU  - E.
AU  - Chipp,
AU  - B.
AU  - Parsons,
AU  - B.
AU  - Totsika,
AU  - V.
AU  - Mandy,
AU  - W.
AU  - Pender,
AU  - R.
AU  - Clery,
AU  - P.
AU  - Lloyd-Evans,
AU  - B.
AU  - Simpson,
AU  - A.
AU  - Johnson,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1017/S0033291724001089
L1  - internal-pdf://2234082108/Pemovska-2024-Approaches to improving mental h.pdf
PY  - 2024
SP  - 1-31
T2  - Psychological Medicine
TI  - Approaches to improving mental health care for autistic children and young people: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1017%2fS0033291724001089
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0B8C35C61254ADFFD8DBCFF7B8BF4BF7/S0033291724001089a.pdf/div-class-title-approaches-to-improving-mental-health-care-for-autistic-children-and-young-people-a-systematic-review-and-meta-analysis-div.pdf
ER  -
TY  - JOUR
AB  - **Background:** 
Schools have a duty of care to prevent violence between students but a significant amount of dating and relationship violence and gender-based violence occurs in schools. These are important public health issues with important longitudinal consequences for young people.

**Objectives:** 
To understand functioning and effectiveness of school-based interventions for the prevention of dating and relationship violence and gender-based violence.

**Review methods:** 
We undertook a mixed-methods systematic review to synthesise different types of evidence relating to school-based interventions for the prevention of dating and relationship violence and gender-based violence to understand if, how and in what ways these interventions are effective. We searched 21 databases and 2 trial registers and undertook forwards and backwards citation chasing, author contact and other supplementary search methods. Searches identified all literature published to June 2021. All screening was undertaken in duplicate and independently, and we quality appraised all included studies.

**Results:** 
We included 247 reports (68 outcome evaluations, 137 process evaluations). Synthesis of intervention components produced an intervention typology: single-component, curricular, multicomponent, and multilevel programmes. Synthesis of intervention theories suggested that interventions aiming to increase students&#039; sense of school belonging and sense of safety in the school building could encourage increased learning of prosocial skills and increased prosocial peer norms, and so potentially reducing dating and relationship violence and gender-based violence. Synthesis of factors affecting delivery highlighted school organisation and leaders who believed in the importance of addressing dating and relationship violence/gender-based violence, along with time and resources to deliver the interventions. The ease with which the intervention could be delivered and modified was also important. Meta-analysis found stronger evidence for intervention effectiveness in reducing dating and relationship violence than for gender-based violence, with significant long-term impacts on dating and relationship violence victimisation and perpetration, and some evidence that interventions in high-income countries could be effective for reducing victimisation and perpetration of gender-based violence in the long-term. Impacts on knowledge and attitudes were primarily short-term. Network meta-analysis did not suggest superiority of any intervention type. Moderation evidence suggested interventions reduced dating and relationship violence perpetration in boys more than girls, but reduced gender-based violence perpetration more in girls. Metaregression by intervention component did not explain heterogeneity in effectiveness, but qualitative comparative analysis suggested that reducing perpetration was important to reducing victimisation, and that perpetration could be reduced via focus on interpersonal skills, guided practice and (for gender-based violence) implementation of social structural components.

**Limitations:** 
Despite an exhaustive search, trials may have been missed and risk of publication bias was high for several analyses.

**Conclusions:** 
This is the most comprehensive systematic review of school-based interventions for dating and relationship violence and gender-based violence to date. It is clear that the prevention of dating and relationship violence and gender-based violence in schools will require longer-term investment to show benefit.
AN  - 38421001
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Orr,
AU  - N.
AU  - Farmer,
AU  - C.
AU  - Shaw,
AU  - N.
AU  - Chollet,
AU  - A.
AU  - Rizzo,
AU  - A.
AU  - J.
AU  - Kiff,
AU  - F.
AU  - Rigby,
AU  - E.
AU  - Hagell,
AU  - A.
AU  - Priolo
AU  - Filho,
AU  - S.
AU  - R.
AU  - Taylor,
AU  - B.
AU  - Young,
AU  - H.
AU  - Bonell,
AU  - C.
AU  - Berry,
AU  - V.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3310/KTWR6997
L1  - internal-pdf://2282435273/Melendez-Torres-2024-School-based intervention.pdf
PY  - 2024
SP  - 1-192
T2  - Public Health Research
TI  - School-based interventions TO Prevent Dating and Relationship Violence and Gender-Based Violence: STOP-DRV-GBV systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=38421001
UR  - https://njl-admin.nihr.ac.uk/document/download/2044842
VL  - 12
ER  -
TY  - JOUR
AB  - Interventions targeting young children&#039;s development may be uniquely impactful in rural areas where resources may be sparse. Following an expansive review of the literature of over 2,200 potential studies, this meta-analysis synthesized the impacts of child-focused interventions implemented within rural settings on key preschool developmental outcomes across 14 experimental/quasi-experimental studies and 90 effects. Random effects models with robust variance estimation revealed that interventions had a significant and moderate impact across child developmental outcomes (delta = 0.44) and for both academic/cognitive (delta = 0.52) and social-behavioral competence (delta = 0.34). Additionally, moderation analyses indicated results to be more pronounced for preschool students of color and students enrolled in Head Start, although findings should be considered in relation to the small sample of included studies. Multicomponent interventions and interventions employing family engagement were also found to significantly contribute to preschool developmental outcomes. Practical implications, study limitations, and future directions are discussed. Impact Statement Child development can be critically supported with interventions addressing academic, behavioral, and/or social-emotional outcomes. Child-focused interventions may be especially impactful in rural areas where key resources may be sparse. The current meta-analysis synthesized key findings of empirical research in this area and offers value insights for school personnel supporting preschool children&#039;s development in rural areas.
AN  - WOS:001317588300001
AU  - Smith,
AU  - T.
AU  - E.
AU  - Stormont,
AU  - M.
AU  - Singell,
AU  - E.
AU  - McGreevy,
AU  - M.
AU  - Reinke,
AU  - W.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1080/2372966x.2024.2399499
L1  - internal-pdf://0749078631/Child-Focused Interventions to Promote the Aca.pdf
PY  - 2024
SP  - 16
T2  - School Psychology Review
TI  - Child-Focused Interventions to Promote the Academic and Social-Behavioral Competence of Rural Preschool Children: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001317588300001
ER  -
TY  - JOUR
AB  - OBJECTIVE: This study aimed to synthesize and encapsulate findings from recent research (May 1, 2018 to August 1, 2023) on neurofeedback interventions for children diagnosed with attention deficit hyperactivity disorder (ADHD). 

METHODS: A comprehensive search was conducted across major databases and platforms, including randomized controlled trials s focusing on children aged 5-11 years with ADHD. The inclusion was broad, not restricted by ADHD subtype, gender, IQ, socioeconomic status, or coexisting conditions. 

RESULTS: From the study screening process, 13 studies were included in the network meta-analysis, involving 1370 children. Most neurofeedback therapies surpassed placebo in ADHD symptoms. In the acceptability outcome, five neurofeedback therapies (HEG, SCP training, TBR training, SMR training, and active control) outperformed the inactive control, physical activity, and EMG therapies. 

CONCLUSIONS: The potential efficacy of nonpharmacological interventions in ADHD management among children is illuminated. The findings advocate for a holistic, child-centered approach, emphasizing the need for further in-depth research to understand and refine these interventions.
AN  - 39711044
AU  - Wu,
AU  - G.
AU  - He,
AU  - Q.
AU  - Li,
AU  - D.
AU  - Zhang,
AU  - Z.
AU  - Miao,
AU  - J.
AU  - Shu,
AU  - Y.
DB  - Desember 2024.enl
DO  - /10.1002/brb3.70194
L1  - internal-pdf://1509291875/Wu-2024-Comparative Efficacy of Neurofeedback.pdf
PY  - 2024
SP  - e70194
T2  - Brain and Behavior
TI  - Comparative Efficacy of Neurofeedback Interventions for Attention-Deficit/Hyperactivity Disorder in Children: A Network Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.1002%2fbrb3.70194
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11664034/pdf/BRB3-14-e70194.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - **Introduction:** Psychosocial intervention is imperative for treating alcohol use disorder (AUD), but there is no comprehensive evidence regarding its effectiveness. Therefore, this study aimed to determine the effectiveness of psychosocial interventions in treating AUD amongadolescents and young adults. 

**Methods:** In this systematic review and meta-analysis, articles were searched from EMBASE, PubMed, Medline, CINAHL, Web of Science, PsycINFO, and Scopus. Also, articles were retrieved from gray literature. The quality of articles has been assessed using the Cochrane risk of bias assessment. 

**Results:** A total of 12 randomized controlled trials were included. Integrated family and CBT, CBT, guided self-change, and ecologically based family therapy had a mild effect in reducing alcohol use frequency. On the other hand, integrated motivational enhancement therapy and CBT (-0.71 [95% CI: -0.97, -0.45]) and common elements treatment approaches (4.5 [95% CI: 6.9, 2.2]) had the highest effect size for reducing alcohol use frequency and amount, respectively. In conclusion, most of the interventions had no significant effect on different drinking outcomes. Nonetheless, the effectiveness of combined interventions surpassed that of the single interventions. The effect of psychosocial interventions on abstinence was inconclusive. Therefore, future studies will explore alternative, newly emerged third-wave therapeutic approaches.

Systematic review registration: PROSPERO, CRD42023435011, https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=435011.
AN  - 39114525
AU  - Belay,
AU  - G.
AU  - M.
AU  - Mak,
AU  - Y.
AU  - W.
AU  - Wong,
AU  - F.
AU  - K.
AU  - Y.
AU  - Lam,
AU  - K.
AU  - K.
AU  - W.
AU  - Liu,
AU  - Q.
AU  - Yang,
AU  - F.
AU  - Mao,
AU  - T.
AU  - Wu,
AU  - C.
AU  - S.
AU  - T.
AU  - Ho,
AU  - K.
AU  - Y.
DB  - August 2024.enl
DO  - /10.3389/fpubh.2024.1371497
L1  - internal-pdf://4039401568/Belay-2024-Psychosocial treatment options for.pdf
PY  - 2024
SP  - 1371497
T2  - Frontiers in Public Health
TI  - Psychosocial treatment options for adolescents and young adults with alcohol use disorder: systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.3389%2ffpubh.2024.1371497
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11303970/pdf/fpubh-12-1371497.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - Background
Pain management is an important part of nursing care for children. The objective of this study was to systematically assess the impact of virtual reality (VR) technology on alleviating the pain and anxiety experienced by children during venipuncture procedures.

Methods
This study searched Pubmed, Web of Sciences, Scopus, The Cochrane Library, Cumulative Index of Nursing and Allied Health Literature (CINAHL), Embase, Medline, China National Knowledge Infrastructure (CNKI), Wanfang, Weipu and China biomedical databases on the randomized controlled trials (RCTs) of virtual reality technology for relieving pain and anxiety associated with venous puncture for children up to July 6, 2024. Risk of bias tool recommended by Cochrane library was used to evaluate the RCT quality. RevMan 5.3 software was used for statistical analysis.

Results
A total of 10 RCTs involving 874 children were included. 429 children received VR intervention during vein puncture. VR was beneficial to reduce the children&rsquo;s self-reported pain scores [SMD=-0.48, 95% CI (&minus;&thinsp;0.61, &minus;&thinsp;0.35)], children&rsquo;s caregivers reported needle-related pain level [SMD=-0.93, 95% CI (-1.45, &minus;&thinsp;0.42)], children&rsquo;s self-reported anxiety scores [SMD=-0.45, 95% CI (&minus;&thinsp;0.65, &minus;&thinsp;0.25)], children&rsquo;s caregivers reported needle-related anxiety level [SMD=-0.47, 95% CI (&minus;&thinsp;0.73, &minus;&thinsp;0.21)]. Egger regression tests indicated that there were no publication biases in the synthesized outcomes (all P&thinsp;&gt;&thinsp;0.05).

Conclusions
VR technology has been shown to effectively mitigate the pain and anxiety experienced by children during venipuncture. Despite the positive findings, more research is needed to better understand the role of VR in children undergoing venipuncture.
AN  - WOS:001286373500004
AU  - Wei,
AU  - Q.
AU  - Sun,
AU  - R.
AU  - Liang,
AU  - Y.
AU  - Chen,
AU  - D.
DB  - September 2024.enl
DO  - 10.1186/s12912-024-02184-5
L1  - internal-pdf://4245773777/Wei-2024-Virtual reality technology reduces th.pdf
PY  - 2024
SP  - 10
T2  - Bmc Nursing
TI  - Virtual reality technology reduces the pain and anxiety of children undergoing vein puncture: a meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001286373500004
UR  - https://link.springer.com/content/pdf/10.1186/s12912-024-02184-5.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - Background: Audiovisual distraction is a potentially good technique to reduce medical treatment procedure-related fear and anxiety among children. However, few studies have assessed its effectiveness. 

Objective&lt;: To conduct a systematic review and meta-analysis for evaluating the effectiveness of audiovisual distraction in reducing pain anxiety in pediatrics. 

Methods: Randomized control trials and experimental studies that reported the use of audiovisual distraction during medical/dental treatments among children aged 3-8 years, used the Face, Legs, Activity, Cry, Consolability (FLACC) scale to assess pain, and were published between 2005-2021 and in English were retrieved from PubMed, Scopus, and Web of Science. A random-effects model was used for evidence analysis. 

Results: A total of four studies were included in the systematic review and meta-analysis: two were from South Asia and one each were from Africa and North America. Three of these studies were randomized control trials. The variability among the studies was high. Three of the four studies found that AV techniques were significantly effective in reducing pain during procedures compared with the control group (P &lt; 0.00001), while one study found no difference; the cumulative evidence in the forest plot was similar. 

Conclusion: Cumulative evidence suggests that the use of audiovisual distraction is an effective strategy in reducing medical/dental procedures-related pain anxiety among children aged 3-8 years. However, evidence on this is currently limited, and thus further studies are required using various AD techniques and on different populations to substantiate these findings. <b>Funding</b>: None. <b>Registration</b>: PROSPERO (Ref no.: CRD42021245874).
AN  - 39055078
AU  - Patil,
AU  - R.
AU  - U.
AU  - Onkari,
AU  - P.
AU  - S.
AU  - Gurunathan,
AU  - D.
DB  - Juli 2024.enl
DO  - /10.4103/sjmms.sjmms_275_23
L1  - internal-pdf://2101754557/effectiveness_of_audiovisual_distraction_in.8.pdf
PY  - 2024
SP  - 252-258
T2  - Saudi Journal of Medicine &amp; Medical Sciences
TI  - Effectiveness of Audiovisual Distraction in Reducing Children&#039;s Anxiety for Pain During Medical and Dental Treatments: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.4103%2fsjmms.sjmms_275_23
VL  - 12
ER  -
TY  - JOUR
AB  - BACKGROUND: The review aimed to investigate the effectiveness of parent-child relationship interventions for families of children with intellectual disability up to 12 years old. 

METHODS: Quasi-experimental or randomised controlled trials (RCTs) of interventions targeting the parent-child relationship where &gt;=50% of children had an intellectual disability were included. Meta-analyses of parent-child relationship outcomes and child outcomes used standardised mean difference as the effect size. 

RESULTS: Twenty-seven papers were included (N = 1325). Parent-child relationship outcomes improved significantly (n = 1325; g = 1.08, 95% CI: 0.64, 1.52) with a large effect size that was robust to sensitivity analyses. Child developmental outcomes improved significantly (n = 1082; g = 0.65, 95% CI: 0.23, 1.07), and indicated a large effect size for child socialisation and communication. 

CONCLUSIONS: Findings suggest that interventions targeting parent-child relationship quality are associated with substantial improvements in parent-child relationship and may improve child outcomes related to socialisation and communication.
AN  - 39192691
AU  - Westlake,
AU  - F.
AU  - Westlake,
AU  - M.
AU  - Totsika,
AU  - V.
DB  - August 2024.enl
DO  - /10.1111/jar.13273
L1  - internal-pdf://3390202577/Westlake-2024-A systematic review and meta-ana.pdf
PY  - 2024
SP  - e13273
T2  - Journal of Applied Research in Intellectual Disabilities
TI  - A systematic review and meta-analysis of the effectiveness of interventions targeting the parent-child relationship in families of children with an intellectual disability
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.1111%2fjar.13273
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jar.13273?download=true
VL  - 37
ER  -
TY  - JOUR
AB  - The Mystery Motivator intervention has been shown to increase prosocial behavior among school-age children by capitalizing on the anticipation afforded by reward concealment or randomization. Although numerous evaluations have supported the effectiveness of the Mystery Motivator, the overall status of this intervention is still unknown. The purpose of the current meta-analysis was to quantify the effects of the Mystery Motivator for improving behavior outcomes in school-age children and determine if participant, setting, and intervention components moderate intervention effects. A systematic review of academic databases was conducted that yielded a total of 24 studies. These studies were evaluated for methodological rigor and analyzed for effects using Tau-U. Results indicate a strong overall effect for this intervention (Tau-U = .77 (CI95 [.73 to .80]). The results discussed and practical issues are considered for future research on the use of the Mystery Motivator to promote the academic and social-emotional development of children and adolescents.
AN  - WOS:001183309000001
AU  - Davis,
AU  - J.
AU  - L.
AU  - King,
AU  - H.
AU  - C.
AU  - Radley,
AU  - K.
AU  - C.
AU  - Corsi,
AU  - C.
AU  - M.
AU  - Jensen,
AU  - H.
AU  - J.
AU  - Jenson,
AU  - W.
AU  - R.
DB  - April 24.enl
DO  - 10.1177/10983007231224048
L1  - internal-pdf://0901461366/davis-et-al-2024-the-mystery-motivator-interve.pdf
PY  - 2024
SP  - 113-127
T2  - Journal of Positive Behavior Interventions
TI  - The Mystery Motivator Intervention for Challenging Behavior: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001183309000001
VL  - 26
ER  -
TY  - JOUR
AB  - **Background:** 
Parenting a child with autism spectrum disorder (ASD) is a major life challenge that leads to negative emotional distress and heavy parent duties. Parent-focused interventions have recently been developed to improve parents&#039; psychosocial well-being in caring for their children with ASD. This study aimed to evaluate the effectiveness of parent-focused interventions on improving psychological health in parents of children with ASD, when compared with active/ inactive controls, and investigate the optimal features of the effective interventions found. 

**Methods:** 
Comprehensive and systematic searches of articles was conducted in PubMed, Embase, PsycINFO, CINAHL, Cochrane Central Register, ProQuest, and CNKI, from their inceptions to 31 December 2022.

**Results:** 
A total of 21 eligible randomized controlled trials (RCTs) were included. The results indicated that the parent-focused intervention group showed reduced stress (Hedge&#039;s g=-1.26), depressive symptoms (g=-0.71), and distress (g=-0.44) in parents and problem behaviours in children (g=-0.21) and improved parent-child relationships (g=0.51) compared with the active/inactive control group post-intervention, with moderate to high certainty of evidence. Moreover, subgroup analyses revealed that mindfulness-based interventions/acceptance commitment therapy (ACT) were the optimal intervention approach for reducing parental stress and depressive symptoms. The optimal intervention duration (five to eight weeks) and target participants (involving only parents) were also identified. 

**Conclusion:** 
As mindfulness-based interventions/ACT were identified as the potentially best approach, future well-designed RCTs are recommended to further examine their effects on both parents and their children with ASD and explore the factors and mechanisms of action influencing the effectiveness of these interventions.
AN  - WOS:001219974100001
AU  - Li,
AU  - S.
AU  - N.
AU  - Chien,
AU  - W.
AU  - T.
AU  - Lam,
AU  - S.
AU  - K.
AU  - K.
AU  - Chen,
AU  - Z.
AU  - Y.
AU  - Ma,
AU  - X.
DB  - Juni 24.enl
DO  - 10.1016/j.rasd.2024.102389
L1  - internal-pdf://0022244383/1-s2.0-S1750946724000643-main.cleaned.pdf
PY  - 2024
SP  - 16
T2  - Research in Autism Spectrum Disorders
TI  - Effectiveness of parent-focused interventions for improving the mental health of parents and their children with autism spectrum disorder: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001219974100001
VL  - 114
ER  -
TY  - JOUR
AB  - Background: Refugees, asylum seekers, and internally displaced people experience a high burden of mental health problems owing to their experiencing traumas and stressful events. 

Objective: To summarise the available evidence and analyse the efficacy of brief psychological interventions (&lt; 3 months) on improving mental health outcomes, including depression, anxiety, and post-traumatic stress disorder (PTSD)-related symptoms in refugees. 

Method: We searched Medline, EMBASE, PsycINFO, CINAHL, and Global Index Medicus from inception to 19 December 2023. We included controlled studies using any cognitive behavioural therapy (CBT) or CBT-based therapies delivered over a short time (&lt; 3 months), which reported mental health outcomes pre-and post-intervention. We conducted meta-analyses using random effects to derive pooled summary statistics. The quality of the evidence was assessed with the Cochrane Risk of Bias (RoB2) and ROBINS-I tools. This study is registered on the Open Science Framework, DOI 10.17605/OSF.IO/9CXU4.

Results: 34 eligible studies across 37 publications were retrieved for analysis, and 33 studies with 4479 participants were included in the meta-analysis. There was an overall improvement in immediate mental health outcomes for all three domains, with analysis of 13 studies on anxiety outcomes (SMD -1.12, 95% CI -1.72 to -0.52), 20 studies on depression (SMD -1.04, 95% CI -1.97 to -0.11), and 24 studies on PTSD (SMD -0.82, 95% CI -1.20 to -0.45). At 3 to 6-month follow-up, however, analysis of mental health outcomes shows no significant change from baseline, with a SMD of 0.24 (95% CI -0.94 to 1.42) across 4 studies, -0.73 (95% CI -2.14 to 0.68) across 9 studies, and 0.29 (95% CI -0.94 to 1.53) across 12 studies for anxiety, depression, and PTSD respectively. 

Conclusion: Low-quality evidence shows brief psychological interventions have a positive immediate effect on refugees and internally displaced people&#039;s mental well-being. However, these effects do not persist in the short-term follow up. Heterogeneity was high, even among subgroups, impacting our findings&#039; generalisability.
AN  - WOS:001303457900001
AU  - Daniel,
AU  - N.
AU  - A.
AU  - Liu,
AU  - X.
AU  - Thomas,
AU  - E.
AU  - T.
AU  - Eraneva-Dibb,
AU  - E.
AU  - Ahmad,
AU  - A.
AU  - Heneghan,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1080/20008066.2024.2389702
L1  - internal-pdf://0392949882/Daniel-2024-Brief CBT-based psychological inte.pdf
PY  - 2024
SP  - 26
T2  - European Journal of Psychotraumatology
TI  - Brief CBT-based psychological interventions to improve mental health outcomes in refugee populations: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001303457900001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/20008066.2024.2389702
VL  - 15
ER  -
TY  - JOUR
AB  - Iron supplementation is commonly recommended for the prevention and treatment of maternal iron deficiency (ID) or iron deficiency anemia (IDA). However, the impacts of prophylactic of therapeutic prenatal iron supplementation on child neurodevelopment in upper middle-income (UMI) and high-income countries (HICs), where broad nutritional deficiencies are less common, are unclear. To investigate this, we conducted a systematic review, searching four databases (Medline, CINAHL, EMBASE, Cochrane Library) through 1 May 2023. Randomized controlled trials (RCTs) assessing oral or intravenous iron supplementation in pregnant women reporting on child neurodevelopment (primary outcome: age-standardized cognitive scores) were eligible. We included three RCTs (five publications) from two HICs (Spain and Australia) (N = 935 children; N = 1397 mothers). Due to clinical heterogeneity of the RCTs, meta-analyses were not appropriate; findings were narratively synthesized. In non-anemic pregnant women, prenatal iron for prevention of IDA resulted in little to no difference in cognition at 40 days post-partum (1 RCT, 503 infants; very low certainty evidence). Similarly, the effect on the intelligence quotient at four years was very uncertain (2 RCTs, 509 children, very low certainty evidence). No RCTs for treatment of ID assessed offspring cognition. The effects on secondary outcomes related to language and motor development, or other measures of cognitive function, were unclear, except for one prevention-focused RCT (302 children), which reported possible harm for children&#039;s behavioral and emotional functioning at four years. There is no evidence from UMI countries and insufficient evidence from HICs to support or refute benefits or harms of prophylactic or therapeutic prenatal iron supplementation on child neurodevelopment.
AN  - 39125379
AU  - Moumin,
AU  - N.
AU  - A.
AU  - Shepherd,
AU  - E.
AU  - Liu,
AU  - K.
AU  - Makrides,
AU  - M.
AU  - Gould,
AU  - J.
AU  - F.
AU  - Green,
AU  - T.
AU  - J.
AU  - Grzeskowiak,
AU  - L.
AU  - E.
DB  - August 2024.enl
DO  - /10.3390/nu16152499
L1  - internal-pdf://0034693998/Moumin-2024-The Effects of Prenatal Iron Suppl.pdf
PY  - 2024
SP  - 31
T2  - Nutrients
TI  - The Effects of Prenatal Iron Supplementation on Offspring Neurodevelopment in Upper Middle- or High-Income Countries: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.3390%2fnu16152499
UR  - https://mdpi-res.com/d_attachment/nutrients/nutrients-16-02499/article_deploy/nutrients-16-02499.pdf?version=1722424379
VL  - 16
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Pain transcends simple physiology, encompassing biological, emotional, psychological, and social facets. Children show pronounced immediate and enduring responses to pain-related procedures. The aim of this meta-analysis is to investigate the efficacy and safety of the Buzzy device for needle-related procedures in children aged twelve years or younger. 

**METHODS**: PubMed, Web of Science, and Embase were searched from inception to July 2023. Only randomized controlled trials utilizing the Buzzy device for needle-related procedures in children under twelve years old were included. Two reviewers independently conducted study selection, data extraction, and risk of bias assessment. Random-effects models were utilized, and analyses were performed using mean differences or standardized mean differences as well as risk ratios. 

**RESULTS**: A total of 19 studies were included, involving 2846 participants (Buzzy = 1095, Control = 1751). Compared to no intervention, the Buzzy device significantly reduced pain response [self-report SMD = -1.90 (-2.45, -1.36), parental SMD = -3.04 (-4.09, -1.99), observer SMD = -2.88 (-3.75, -2.02)] and anxiety scores [self-report SMD = -1.97 (-3.05, -0.88), parental SMD = -2.01 (-2.93, -1.08), observer SMD = -1.92 (-2.64, -1.19)]. Compared to virtual reality (VR), the Buzzy device reduced self-reported anxiety levels SMD = -0.47 (-0.77, -0.17), and compared to distraction cards, the Buzzy device reduced parental and observer-reported pain [parental SMD = -0.85 (-1.22, -0.48), observer SMD = -0.70 (-1.00, -0.40)] and anxiety [parental SMD = -0.96 (-1.46, -0.47), observer SMD = -0.91 (-1.40, -0.42)]. Subgroup analysis results showed that procedure type, patient age, measurement scales used, and distance of operation were not the reason of heterogeneity. The summarized first puncture attempt success rate did not differ from other interventions. There were no significant adverse events in the included studies.

 **CONCLUSION**: The Buzzy device reduces pain and anxiety in children during needle procedures, ensuring success and safety. Additionally, the effectiveness of the Buzzy device in reducing pain during venipuncture is superior when compared to its effectiveness during intramuscular injections.
AN  - 38608108
AU  - Jin,
AU  - F.
AU  - Wang,
AU  - X.
AU  - Qi,
AU  - M.
AU  - Zhang,
AU  - W.
AU  - Zhang,
AU  - Y.
DB  - April 24.enl
DO  - /10.1097/MD.0000000000037522
L1  - internal-pdf://2606416672/Jin-2024-Effectiveness and safety of Buzzy dev.pdf
PY  - 2024
SP  - e37522
T2  - Medicine
TI  - Effectiveness and safety of Buzzy device in needle-related procedures for children under twelve years of age: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1097%2fMD.0000000000037522
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11018245/pdf/medi-103-e37522.pdf
VL  - 103
ER  -
TY  - JOUR
AB  - Arts therapy is a popular intervention used to work through the effects of traumatic experience. We evaluate previous reviews and report a meta-analysis of the effectiveness of arts therapy following trauma for reducing symptoms of PTSD, enhancing positive outcomes (e.g., quality of life) and decreasing negative outcomes (e.g., depression). Database searches identified 21 (N = 868) randomised controlled trials (RCTs). Outcomes were categorised as PTSD specific, positive non-PTSD specific and negative non-PTSD specific. Several moderators were tested: age, diagnosis type, trauma type, intervention instruction, control type, therapy mode and therapy duration. Overall, random-effects analysis indicated that arts therapy was favoured relative to control for positive non-PTSD-specific outcomes (g = 1.53, p &lt; 0.001), but not for negative non-PTSD-specific (p = 0.069) or PTSD-specific outcomes (g = 0.89, p = 0.052). Regression analyses indicated that arts therapy was effective in reducing PTSD-specific outcomes in children (Z = 2.81, df = 1, p = 0.005), positive non-PTSD-specific outcomes in group-based arts therapy (Z = -2.40, df = 1, p = 0.016, I&lt;sup&gt;2&lt;/sup&gt; = 57.33) and for reducing negative non-PTSD outcomes following acute traumas (e.g., combat-related trauma or sexual abuse) (Q = 10.70, df = 3, p = 0.013, I&lt;sup&gt;2&lt;/sup&gt; = 77.09). We highlight the need for additional RCTs and standardised protocols to address heterogeneity. Our review provides an important benchmark for gauging the effectiveness of arts therapy in the treatment of trauma.
AN  - 39120099
AU  - Maddox,
AU  - G.
AU  - A.
AU  - Bodner,
AU  - G.
AU  - E.
AU  - Christian,
AU  - M.
AU  - W.
AU  - Williamson,
AU  - P.
DB  - August 2024.enl
DO  - /10.1002/cpp.3041
L1  - internal-pdf://3301597593/Maddox-2024-On the Effectiveness of Visual Art.pdf
PY  - 2024
SP  - e3041
T2  - Clinical Psychology &amp; Psychotherapy
TI  - On the Effectiveness of Visual Arts Therapy for Traumatic Experiences: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1002%2fcpp.3041
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpp.3041?download=true
VL  - 31
ER  -
TY  - JOUR
AB  - BACKGROUND: The efficacy of probiotics as a therapeutic alternative for attention-deficit hyperactivity disorder (ADHD) remain unclear. 

AIMS: To investigate the effectiveness of probiotics for symptoms of ADHD and identify possible factors affecting their efficacy. 

METHOD: Randomised placebo-controlled trials were identified through searching major databases from inception to April 2023, using the main keywords &#039;probiotics&#039; and &#039;ADHD&#039; without limitation on languages or geographic locations. The outcome of interest included improvement in total symptoms of ADHD, symptoms of inattention and hyperactivity/impulsivity, and drop-out rate. Continuous and categorical data were expressed as effect sizes based on standardised mean differences (SMDs) and odds ratios, respectively, with 95% confidence intervals. 

RESULTS: Meta-analysis of seven trials involving 379 participants (mean age 10.37 years, range 4-18 years) showed no significant improvement in total symptoms of ADHD (SMD = 0.25; P = 0.12), symptoms of inattention (SMD = 0.14; P = 0.3) or hyperactivity/impulsivity (SMD = 0.08; P = 0.54) between the probiotic and placebo groups. Despite non-significance on subgroup analyses, there was a large difference in effect size between studies using probiotics as an adjunct to methylphenidate and those using probiotics as supplementation (SMD = 0.84 v. 0.07; P = 0.16), and a moderate difference in effect size between studies using multiple strains of probiotics and those using single-strain regimens (SMD = 0.45 v. 0.03; P = 0.19). 

CONCLUSIONS: Current evidence shows no significant difference in therapeutic efficacy between probiotics and placebos for treatment of ADHD symptoms. However, albeit statistically non-significant, higher therapeutic efficacies associated with multiple-strain probiotics or combining probiotics with methylphenidate may provide direction for further research.
AN  - 38268113
AU  - Liang,
AU  - S.
AU  - C.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Chang,
AU  - C.
AU  - H.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Tzang,
AU  - R.
AU  - F.
AU  - Chiu,
AU  - H.
AU  - J.
AU  - Wang,
AU  - M.
AU  - Y.
AU  - Cheng,
AU  - Y.
AU  - C.
AU  - Hung,
AU  - K.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/bjo.2023.645
L1  - internal-pdf://1891533364/Liang-2024-Therapeutic efficacy of probiotics.pdf
PY  - 2024
SP  - e36
T2  - Bjpsych Open
TI  - Therapeutic efficacy of probiotics for symptoms of attention-deficit hyperactivity disorder in children and adolescents: meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=38268113
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/307B11FCC575B8AC36D5249175C8A9CB/S2056472423006452a.pdf/div-class-title-therapeutic-efficacy-of-probiotics-for-symptoms-of-attention-deficit-hyperactivity-disorder-in-children-and-adolescents-meta-analysis-div.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - Culturally responsive interventions for autistic children and their families have been developed and implemented to address issues related to limited representation, inequities, and disparities in access to care of minoritized families in research. Currently available reviews are relatively limited in scope or do not synthesize interventions specifically. Therefore, we conducted a meta-analysis to synthesize autism intervention literature that specifically targeted autistic individuals and their family members from minoritized backgrounds, such as immigrant families. We used four databases to identify studies that used culturally responsive interventions with minoritized autistic children and their families. An article was included if it included empirical intervention data using an experimental design. A total of 354 studies were initially screened, and 24 studies were included. Effect sizes of these studies were extracted across two levels (i.e., child and family levels). Data from group design studies were extracted manually, and data from single-case design studies were extracted using a web-based tool. We used design-comparable standardized effect sizes to compare across both designs. The analysis revealed a large, positive, and significant overall effect size across culturally responsive interventions. Specifically, social-communication and mental health outcomes yielded significant effects at the child level. Additionally, parents&#039; mental health and fidelity of strategy implementation also yielded significant results. Our results suggest that culturally responsive interventions yield comparable outcomes to unadapted, original interventions. Future research should examine the distinction between the effect of cultural adaptation and the efficacy of the intervention itself.
AN  - 38246962
AU  - Lee,
AU  - J.
AU  - D.
AU  - Kang,
AU  - V.
AU  - Y.
AU  - Terol,
AU  - A.
AU  - K.
AU  - Joo,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-023-06212-2
L1  - internal-pdf://1145602393/Lee-2024-Examining the Efficacy of Culturally.pdf
PY  - 2024
SP  - 21
T2  - Journal of Autism &amp; Developmental Disorders
TI  - Examining the Efficacy of Culturally Responsive Interventions for Autistic Children and Their Families: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38246962
UR  - https://link.springer.com/article/10.1007/s10803-023-06212-2
UR  - https://link.springer.com/content/pdf/10.1007/s10803-023-06212-2.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - BACKGROUND: Emotion dysregulation (ED), the difficulty in modulating which emotions are felt, and when and how they are expressed or experienced, has been implicated in an array of psychological disorders. Despite potentially different manifestations depending on the disorder, this symptom is emerging as a transdiagnostic construct that can and should be targeted early, given the associations with various maladaptive behaviors as early as childhood and adolescence. As such, our goal was to investigate the psychotherapeutic interventions used to address ED and gauge their effectiveness, safety, and potential mechanisms across various populations. 

METHODS: This umbrella systematic review, pre-registered under PROSPERO (registration: CRD42023411452), consolidates evidence from systematic reviews and meta-analyses on psychotherapeutic interventions targeting ED, in accordance with PRISMA guidelines. 

RESULTS: Our synthesis of quantitative and qualitative evidence from 21 systematic reviews (including 11 meta-analyses) points-with moderate overall risk of bias-to the effectiveness of Dialectical Behavior Therapy and Cognitive Behavioral Therapy in reducing ED in a wide range of adult transdiagnostic psychiatric patients and healthy participants. Similar results have emerged in other less extensively researched methods as well. However, results on adolescents and children are sparse, highlighting the need for additional research to tailor these interventions to the unique challenges of ED in younger populations with diverse externalizing and internalizing disorders. 

CONCLUSIONS: These demonstrated transdiagnostic advantages of psychotherapy for ED underscore the potential for specifically designed interventions that address this issue directly, particularly for high-risk individuals. In these individuals, early interventions targeting transdiagnostic core dimensions may mitigate the emergence of full-blown disorders. Future research on the mediating factors, the durability of intervention effects, and the exploration of understudied interventions and populations may enhance prevention and treatment efficiency, enhancing the quality of life for those affected by varied manifestations of ED.
AN  - 38677089
AU  - Saccaro,
AU  - L.
AU  - F.
AU  - Giff,
AU  - A.
AU  - De
AU  - Rossi,
AU  - M.
AU  - M.
AU  - Piguet,
AU  - C.
DB  - April 24.enl
DO  - /10.1016/j.jpsychires.2024.04.025
L1  - internal-pdf://3000942470/1-s2.0-S0022395624002310-main.cleaned.pdf
PY  - 2024
SP  - 263-274
T2  - Journal of Psychiatric Research
TI  - Interventions targeting emotion regulation: A systematic umbrella review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jpsychires.2024.04.025
UR  - https://www.sciencedirect.com/science/article/pii/S0022395624002310?via%3Dihub
VL  - 174
ER  -
TY  - JOUR
AB  - OBJECTIVE: To compare second-generation antipsychotics (SGAs) and mood stabilizers (MSs) in youth with a bipolar disorder type I (BD-I) manic/mixed episode. 

METHOD: A systematic PubMed/Embase/PsycInfo literature search until December 31, 2023, for randomized trials of SGAs or MSs in patients &lt;=18 years of age with BD-I manic/mixed episode was conducted. The study included a network meta-analysis comparing treatments regarding mania symptoms and mania response (co-primary outcomes), and secondary efficacy and tolerability outcomes. 

RESULTS: Eighteen studies (n = 2844, mean age = 11.74, female participants = 48.0%, mean study duration = 5.4 weeks) comparing 6 SGAs (aripiprazole, asenapine, olanzapine, quetiapine, risperidone, and ziprasidone) and 4 MSs (lithium, oxcarbazepine, topiramate, and valproate) were meta-analyzed. All 6 SGAs outperformed placebo in reducing manic symptomatology, including risperidone (standardized mean difference [SMD] = -1.18, 95% CI = -0.92, -1.45, Confidence in Network Meta-Analysis [CINeMA] = moderate confidence), olanzapine (SMD = -0.77, 95% CI = -0.36, -1.18, low confidence), aripiprazole (SMD = -0.67, 95% CI = -0.33, -1.01, moderate confidence), quetiapine (SMD = -0.60, 95% CI = -0.32, -0.87, high confidence), asenapine (SMD = -0.54, 95% CI = -0.19, -0.89, moderate confidence), and ziprasidone (SMD = -0.43, 95% CI = -0.17, 0.70, low confidence), whereas no mood stabilizer outperformed placebo. Concerning mania response, risperidone (RR = 2.58, 95% CI = 1.88, 3.54, low confidence), olanzapine (RR = 2.42, 95% CI = 1.33, 3.54, very low confidence), aripiprazole (RR = 2.05, 95% CI = 1.44, 2.92, low confidence), quetiapine (RR = 1.89, 95% CI = 1.45n 2.47, moderate confidence), asenapine (RR = 1.81, 95% CI = 1.28, 2.55, very low confidence) and lithium (RR = 1.35, 95% CI = 1.00, 1.83, p = .049, very low confidence) outperformed placebo, without superiority of other MSs vs placebo. Individually, risperidone was more efficacious in reducing manic symptomatology than all other comparators, except olanzapine and topiramate, yet with low/very low confidence, and was associated with increased prolactin and glucose. Pooled together, SGAs outperformed both placebo and MSs for mania symptom reduction (SMD = -0.68, 95% CI = -0.86, -0.51 and SMD = -0.61, 95% CI = -0.82, -0.40, moderate confidence), and mania response (RR = 1.85, 95% CI = 1.53, 2.24 and RR = 1.65, 95% CI = 1.33, 2.04, moderate confidence) without differences between MSs and placebo. There were no significant treatment-placebo differences for all-cause discontinuation, whereas lithium, ziprasidone, and oxcarbazepine were associated with more adverse event-related drop-outs than placebo. Most SGAs were associated with more sedation, weight gain, and metabolic issues vs placebo and MSs. 

CONCLUSION: SGAs were more efficacious than placebo and MSs in treating acute mania symptoms, however, their use must be carefully weighed against important side effects.
AN  - 39128561
AU  - Vita,
AU  - G.
AU  - Nohles,
AU  - V.
AU  - B.
AU  - Ostuzzi,
AU  - G.
AU  - Barbui,
AU  - C.
AU  - Tedeschi,
AU  - F.
AU  - Heuer,
AU  - F.
AU  - H.
AU  - Keller,
AU  - A.
AU  - DelBello,
AU  - M.
AU  - P.
AU  - Welge,
AU  - J.
AU  - A.
AU  - Blom,
AU  - T.
AU  - J.
AU  - Kowatch,
AU  - R.
AU  - A.
AU  - Correll,
AU  - C.
AU  - U.
DB  - August 2024.enl
DO  - /10.1016/j.jaac.2024.07.920
L1  - internal-pdf://0243621531/1-s2.0-S0890856724013169-main.pdf
PY  - 2024
SP  - 09
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Systematic Review and Network Meta-Analysis: Efficacy and Safety of Antipsychotics vs Antiepileptics or Lithium for Acute Mania in Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jaac.2024.07.920
VL  - 09
ER  -
TY  - JOUR
AB  - Review Rationale and Context
Many intervention studies of summer programmes examine their impact on employment and education outcomes, however there is growing interest in their effect on young people&#039;s offending outcomes. Evidence on summer employment programmes shows promise on this but has not yet been synthesised. This report fills this evidence gap through a systematic review and meta-analysis, covering summer education and summer employment programmes as their contexts and mechanisms are often similar.

Research Objective
The objective is to provide evidence on the extent to which summer programmes impact the outcomes of disadvantaged or &lsquo;at risk&rsquo; young people.

Methods
The review employs mixed methods: we synthesise quantitative information estimating the impact of summer programme allocation/participation across the outcome domains through meta-analysis using the random-effects model; and we synthesise qualitative information relating to contexts, features, mechanisms and implementation issues through thematic synthesis. Literature searches were largely conducted in January 2023. Databases searched include: Scopus; PsychInfo; ERIC; the YFF-EGM; EEF&#039;s and TASO&#039;s toolkits; RAND&#039;s summer programmes evidence review; key academic journals; and Google Scholar. The review employed PICOSS eligibility criteria: the population was disadvantaged or &lsquo;at risk&rsquo; young people aged 10&ndash;25; interventions were either summer education or employment programmes; a valid comparison group that did not experience a summer programme was required; studies had to estimate the summer programme&#039;s impact on violence and offending, education, employment, socio-emotional and/or health outcomes; eligible study designs were experimental and quasi-experimental; eligible settings were high-income countries. Other eligibility criteria included publication in English, between 2012 and 2022. Process/qualitative evaluations associated with eligible impact studies or of UK-based interventions were also included; the latter given the interests of the sponsors. We used standard methodological procedures expected by The Campbell Collaboration. The search identified 68 eligible studies; with 41 eligible for meta-analysis. Forty-nine studies evaluated 36 summer education programmes, and 19 studies evaluated six summer employment programmes. The number of participants within these studies ranged from less than 100 to nearly 300,000. The PICOSS criteria affects the external applicability of the body of evidence &ndash; allowances made regarding study design to prioritise evidence on UK-based interventions limits our ability to assess impact for some interventions. The risk of bias assessment categorised approximately 75% of the impact evaluations as low quality, due to attrition, losses to follow up, interventions having low take-up rates, or where allocation might introduce selection bias. As such, intention-to-treat analyses are prioritised. The quality assessment rated 93% of qualitative studies as low quality often due to not employing rigorous qualitative methodologies. These results highlight the need to improve the evidence.

Results and Conclusions
Quantitative synthesis The quantitative synthesis examined impact estimates across 34 outcomes, through meta-analysis (22) or in narrative form (12). We summarise below the findings where meta-analysis was possible, along with the researchers&#039; judgement of the security of the findings (high, moderate or low). This was based on the number and study-design quality of studies evaluating the outcome; the consistency of findings; the similarity in specific outcome measures used; and any other specific issues which might affect our confidence in the summary findings.

Below we summarise the findings from the meta-analyses conducted to assess the impact of allocation to/participation in summer education and employment programmes (findings in relation to other outcomes are also discussed in the main body, but due to the low number of studies evaluating these, meta-analysis was not performed). We only cover the pooled results for the two programme types where there are not clear differences in findings between summer education and summer employment programmes, so as to avoid potentially attributing any impact to both summer programme types when this is not the case. We list the outcome measure, the average effect size type (i.e., whether a standardised mean difference (SMD) or log odds ratio), which programme type the finding is in relation to and then the average effect size along with its 95% confidence interval and the interpretation of the finding, that is, whether there appears to be a significant impact and in which direction (positive or negative, clarifying instances where a negative impact is beneficial). In some instances there may be a discrepancy between the 95% confidence interval and whether we determine there to be a significant impact, which will be due to the specifics of the process for constructing the effect sizes used in the meta-analysis. We then list the I2 statistic and the p-value from the homogeneity test as indications of the presence of heterogeneity. As the sample size used in the analysis are often small and the homogeneity test is known to be under-powered with small sample sizes, it may not detect statistically significant heterogeneity when it is in fact present. As such, a 90% confidence level threshold should generally be used when interpreting this with regard to the meta-analyses below. The presence of effect size heterogeneity affects the extent to which the average effects size is applicable to all interventions of that summer programme type. We also provide an assessment of the relative confidence we have in the generalisability of the overall finding (low, moderate or high) &ndash; some of the overall findings are based on a small sample of studies, the studies evaluating the outcome may be of low quality, there may be wide variation in findings among the studies evaluating the outcome, or there may be specific aspects of the impact estimates included or the effect sizes constructed that affect the generalisability of the headline finding. These issues are detailed in full in the main body of the review.

&ndash;Engagement with/participation in/enjoyment of education (SMD):

∘Summer education programmes: +0.12 (+0.03, +0.20); positive impact; I2&thinsp;=&thinsp;48.76%, p&thinsp;=&thinsp;0.10; moderate confidence.

&ndash;Secondary education attendance (SMD):

∘Summer education programmes: +0.26 (+0.08, +0.44); positive impact; I2&thinsp;=&thinsp;N/A; p&thinsp;=&thinsp;N/A; low confidence.

∘Summer employment programmes: +0.02 (&minus;0.03, +0.07); no impact; I2&thinsp;=&thinsp;69.98%; p&thinsp;=&thinsp;0.03; low confidence.

&ndash;Passing tests (log OR):

∘Summer education programmes: +0.41 (&minus;0.13, +0.96); no impact; I2&thinsp;=&thinsp;95.05%; p&thinsp;=&thinsp;0.00; low confidence.

∘Summer employment programmes: +0.02 (+0.00, +0.04); positive impact; I2&thinsp;=&thinsp;0.01%; p&thinsp;=&thinsp;0.33; low confidence.

&ndash;Reading test scores (SMD):

∘Summer education programmes: +0.01 (&minus;0.04, +0.05); no impact; I2&thinsp;=&thinsp;0.40%; p&thinsp;=&thinsp;0.48; high confidence.

&ndash;English test scores (SMD):

∘Summer education programmes: +0.07 (+0.00, +0.13); positive impact; I2&thinsp;=&thinsp;27.17%; p&thinsp;=&thinsp;0.33; moderate confidence.

∘Summer employment programmes: &minus;0.03 (&minus;0.05, &minus;0.01); negative impact; I2&thinsp;=&thinsp;0.00%; p&thinsp;=&thinsp;0.76; low confidence.

&ndash;
Mathematics test scores (SMD):

∘All summer programmes: +0.09 (&minus;0.06, +0.25); no impact; I2&thinsp;=&thinsp;94.53%; p&thinsp;=&thinsp;0.00; high confidence.

∘Summer education programmes: +0.14 (&minus;0.09, +0.36); no impact; I2&thinsp;=&thinsp;94.15%; p&thinsp;=&thinsp;0.00; moderate confidence.

∘Summer employment programmes: +0.00 (&minus;0.04, +0.05); no impact; I2&thinsp;=&thinsp;0.04%; p&thinsp;=&thinsp;0.92; moderate confidence.

&ndash;Overall test scores (SMD):

∘Summer employment programmes: &minus;0.01 (&minus;0.08, +0.05); no impact; I2&thinsp;=&thinsp;32.39%; p&thinsp;=&thinsp;0.20; high confidence.

&ndash;All test scores (SMD):

∘Summer education programmes: +0.14 (+0.00, +0.27); positive impact; I2&thinsp;=&thinsp;91.07%; p&thinsp;=&thinsp;0.00; moderate confidence.

∘Summer employment programmes: &minus;0.01 (&minus;0.04, +0.01); no impact; I2&thinsp;=&thinsp;0.06%; p&thinsp;=&thinsp;0.73; high confidence.

&ndash;Negative behavioural outcomes (log OR):

∘Summer education programmes: &minus;1.55 (&minus;3.14, +0.03); negative impact; I2&thinsp;=&thinsp;N/A; p&thinsp;=&thinsp;N/A; low confidence.

∘Summer employment programmes: &minus;0.07 (&minus;0.33, +0.18); no impact; I2&thinsp;=&thinsp;88.17%; p&thinsp;=&thinsp;0.00; moderate confidence.

&ndash;Progression to HE (log OR):

∘All summer programmes: +0.24 (&minus;0.04, +0.52); no impact; I2&thinsp;=&thinsp;97.37%; p&thinsp;=&thinsp;0.00; low confidence.

∘Summer education programmes: +0.32 (&minus;0.12, +0.76); no impact; I2&thinsp;=&thinsp;96.58%; p&thinsp;=&thinsp;0.00; low confidence.

∘Summer employment programmes: +0.10 (&minus;0.07, +0.26); no impact; I2&thinsp;=&thinsp;76.61%; p&thinsp;=&thinsp;0.02; moderate confidence.

&ndash;Complete HE (log OR):

∘Summer education programmes: +0.38 (+0.15, +0.62); positive impact; I2&thinsp;=&thinsp;52.52%; p&thinsp;=&thinsp;0.06; high confidence.

∘Summer employment programmes: +0.07 (&minus;0.19, +0.33); no impact; I2&thinsp;=&thinsp;70.54%; p&thinsp;=&thinsp;0.07; moderate confidence.

&ndash;Entry to employment, short-term (log OR):

∘Summer employment programmes: &minus;0.19 (&minus;0.45, +0.08); no impact; I2&thinsp;=&thinsp;87.81%; p&thinsp;=&thinsp;0.00; low confidence.

∘Entry to employment, full period (log OR)

∘Summer employment programmes: &minus;0.15 (&minus;0.35, +0.05); no impact; I2&thinsp;=&thinsp;78.88%; p&thinsp;=&thinsp;0.00; low confidence.

&ndash;Likelihood of having a criminal justice outcome (log OR):

∘Summer employment programmes: &minus;0.05 (&minus;0.15, +0.05); no impact; I2&thinsp;=&thinsp;0.00%; p&thinsp;=&thinsp;0.76; low confidence.

&ndash;Likelihood of having a drug-related criminal justice outcome (log OR):

∘Summer employment programmes: +0.16 (&minus;0.57, +0.89); no impact; I2&thinsp;=&thinsp;65.97%; p&thinsp;=&thinsp;0.09; low confidence.

&ndash;Likelihood of having a violence-related criminal justice outcome (log OR):

∘Summer employment programmes: +0.03 (&minus;0.02, +0.08); no impact; I2&thinsp;=&thinsp;0.00%; p&thinsp;=&thinsp;0.22; moderate confidence.

&ndash;Likelihood of having a property-related criminal justice outcome (log OR):

∘Summer employment programmes: +0.09 (&minus;0.17, +0.34); no impact; I2&thinsp;=&thinsp;45.01%; p&thinsp;=&thinsp;0.18; low confidence.

&ndash;Number of criminal justice outcomes, during programme (SMD):

∘Summer employment programmes: &minus;0.01 (&minus;0.03, +0.00); no impact; I2&thinsp;=&thinsp;2.17%; p&thinsp;=&thinsp;0.31; low confidence.

&ndash;Number of criminal justice outcomes, post-programme (SMD):

∘Summer employment programmes: &minus;0.01 (&minus;0.03, +0.00); no impact; I2&thinsp;=&thinsp;23.57%; p&thinsp;=&thinsp;0.37; low confidence.

&ndash;Number of drug-related criminal justice outcomes, post-programme (SMD):

∘Summer employment programmes: &minus;0.01 (&minus;0.06, +0.06); no impact; I2&thinsp;=&thinsp;55.19%; p&thinsp;=&thinsp;0.14; moderate confidence.

&ndash;Number of violence-related criminal justice outcomes, post-programme (SMD):

∘Summer employment programmes: &minus;0.02 (&minus;0.08, +0.03); no impact; I2&thinsp;=&thinsp;44.48%; p&thinsp;=&thinsp;0.18; low confidence.

&ndash;Number of property-related criminal justice outcomes, post-programme (SMD):

∘Summer employment programmes: &minus;0.02 (&minus;0.10, +0.05); no impact; I2&thinsp;=&thinsp;64.93%; p&thinsp;=&thinsp;0.09; low confidence.

We re-express instances of significant impact by programme type where we have moderate or high confidence in the security of findings by translating this to a form used by one of the studies, to aid understanding of the findings. Allocation to a summer education programme results in approximately 60% of individuals moving from never reading for fun to doing so once or twice a month (engagement in/participation in/enjoyment of education), and an increase in the English Grade Point Average of 0.08. Participation in a summer education programme results in an increase in overall Grade Point Average of 0.14 and increases the likelihood of completing higher education by 1.5 times. Signs are positive for the effectiveness of summer education programmes in achieving some of the education outcomes considered (particularly on test scores (when pooled across types), completion of higher education and STEM-related higher education outcomes), but the evidence on which overall findings are based is often weak. Summer employment programmes appear to have a limited impact on employment outcomes, if anything, a negative impact on the likelihood of entering employment outside of employment related to the programme. The evidence base for impacts of summer employment programmes on young people&#039;s violence and offending type outcomes is currently limited &ndash; where impact is detected this largely results in substantial reductions in criminal justice outcomes, but the variation in findings across and within studies affects our ability to make any overarching assertions with confidence. In understanding the effectiveness of summer programmes, the order of outcomes also requires consideration &ndash; entries into education from a summer employment programme might be beneficial if this leads towards better quality employment in the future and a reduced propensity of criminal justice outcomes.

Qualitative Synthesis
Various shared features among different summer education programmes emerged from the review, allowing us to cluster specific types of these interventions which then aided the structuring of the thematic synthesis. The three distinct clusters for summer education programmes were: catch-up programmes addressing attainment gaps, raising aspirations programmes inspiring young people to pursue the next stage of their education or career, and transition support programmes facilitating smooth transitions between educational levels. Depending on their aim, summer education programme tend to provide a combination of: additional instruction on core subjects (e.g., English, mathematics); academic classes including to enhance specialist subject knowledge (e.g., STEM-related); homework help; coaching and mentoring; arts and recreation electives; and social and enrichment activities. Summer employment programmes provide paid work placements or subsidised jobs typically in entry-level roles mostly in the third and public sectors, with some summer employment programmes also providing placements in the private sector. They usually include components of pre-work training and employability skills, coaching and mentoring. There are a number of mechanisms which act as facilitators or barriers to engagement in summer programmes. These include tailoring the summer programme to each young person and individualised attention; the presence of well-prepared staff who provide effective academic/workplace and socio-emotional support; incentives of a monetary (e.g., stipends and wages) or non-monetary (e.g., free transport and meals) nature; recruitment strategies, which are effective at identifying, targeting and engaging participants who can most benefit from the intervention; partnerships, with key actors who can help facilitate referrals and recruitment, such as schools, community action and workforce development agencies; format, including providing social activities and opportunities to support the formation of connections with peers; integration into the workplace, through pre-placement engagement, such as through orientation days, pre-work skills training, job fairs, and interactions with employers ahead of the beginning of the summer programme; and skill acquisition, such as improvements in social skills. In terms of the causal processes which lead from engagement in a summer programme to outcomes, these include: skill acquisition, including academic, social, emotional, and life skills; positive relationships with peers, including with older students as mentors in summer education programmes; personalised and positive relationships with staff; location, including accessibility and creating familiar environments; creating connections between the summer education programme and the students&#039; learning at home to maintain continuity and reinforce learning; and providing purposeful and meaningful work through summer employment programmes (potentially facilitated through the provision of financial and/or non-financial incentives), which makes participants more likely to see the importance of education in achieving their life goals and this leads to raised aspirations. It is important to note that no single element of a summer programme can be identified as generating the causal process for impact, and impact results rather from a combination of elements. Finally, we investigated strengths and weaknesses in summer programmes at both the design and implementation stages. In summer education programmes, design strengths include interactive and alternative learning modes; iterative and progressive content building; incorporating confidence building activities; careful lesson planning; and teacher support which is tailored to each student. Design weaknesses include insufficient funding or poor funding governance (e.g., delays to funding); limited reach of the target population; and inadequate allocation of teacher and pupil groups (i.e., misalignment between the education stage of the pupils and the content taught by staff). Implementation strengths include clear programme delivery guidance and good governance; high quality academic instruction; mentoring support; and strong partnerships. Implementation weaknesses include insufficient planning and lead in time; recruitment challenges; and variability in teaching quality. In summer employment programmes, design strengths include use of employer orientation materials and supervisor handbooks; careful consideration of programme staff roles; a wide range of job opportunities; and building a network of engaged employers. Design weaknesses are uncertainty over funding and budget agreements; variation in delivery and quality of training between providers; challenges in recruitment of employers; and caseload size and management. Implementation strengths include effective job matching; supportive relationships with supervisors; pre-work training; and mitigating attrition (e.g., striving to increase take up of the intervention among the treatment group). Implementation weaknesses are insufficient monitors for the number of participants, and challenges around employer availability.
AU  - Muir,
AU  - D.,
AU  - Orlando,
AU  - C.,
AU  - Newton,
AU  - B.
DB  - Juli 2024.enl
DO  - /10.1002/cl2.1406
L1  - internal-pdf://0825552561/Campbell Systematic Reviews - 2024 - Muir - Im.pdf
PY  - 2024
T2  - Campbell Systematic Reviews
TI  - Impact of summer programmes on the outcomes of disadvantaged or &lsquo;at risk&rsquo; young people: A systematic review
ER  -
TY  - JOUR
AB  - This comprehensive meta-analysis aimed to assess the effectiveness of digital interventions in improving developmental skills for children and adolescents with autism spectrum disorder (ASD). We conducted a systematic literature search based on three databases. A pre-test adjusted between-group standardized effect size was computed for effect size synthesis. We utilized a robust variance estimation model to analyze overall treatment effect. Moderator analyses and publication bias were also addressed. Twenty-eight studies (150 effect sizes) using randomized control trials (RCT; n = 22) or quasi-experimental designs (QED; n = 6) were included. Most studies (n = 22) included social-emotional skills as primary outcomes. The meta-analysis revealed a medium to large overall effect size, with Hedges&#039; g = 0.62, 95% CI [0.36, 0.88], p &lt; 0.001. We found that digital interventions have a statistically significantly large effect on enhancing social-emotional skills compared with language and communication skills, cognitive skills, daily living skills, and physical skills. The results of moderator analyses indicated that computer-based interventions have larger effect sizes in comparison to tablet/smartphone-based interventions. No statistically significant differences were observed between studies utilizing RCT and those using QED. We recommended the integration of digital interventions as supplemental resources in behavioral and educational interventions. Further research needs to focus on more females, young children, and adolescents with ASD in digital intervention research.
AN  - 39325282
AU  - Xu,
AU  - F.
AU  - Gage,
AU  - N.
AU  - Zeng,
AU  - S.
AU  - Zhang,
AU  - M.
AU  - Iun,
AU  - A.
AU  - O&#039;Riordan,
AU  - M.
AU  - Kim,
AU  - E.
DB  - September 2024.enl
DO  - /10.1007/s10803-024-06563-4
L1  - internal-pdf://0399662482/s10803-024-06563-4.cleaned.pdf
PY  - 2024
SP  - 26
T2  - Journal of Autism &amp; Developmental Disorders
TI  - The Use of Digital Interventions for Children and Adolescents with Autism Spectrum Disorder-A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs10803-024-06563-4
UR  - https://link.springer.com/article/10.1007/s10803-024-06563-4
VL  - 26
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Children all over the world are subjected to torture, but few are identified as victims of these actions. Knowledge that facilitates identification, documentation, and treatment of torture injuries in children can allow redress and rehabilitation for more children in need. **OBJECTIVE**: To synthesise research regarding screening, documentation, and treatment of child survivors of torture. **METHODS**: A systematic literature review was conducted. A total of 4795 titles and/or abstracts were screened, of which 80 articles were included. Grey literature was also included. **RESULTS**: Screening for torture exposure usually consisted of questions that were included in trauma questionnaires. Questions about perpetrators in the traumatic events were missing from more than half of the studies. Although children were screened mainly for psychological injuries, it was primarily physical injuries that were documented. The evidence on treatment effects was limited. However, there was a tendency that Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) and Narrative Exposure Therapy (NET) significantly reduced PTSD up to three months to one year after the end of treatment. Treatments with individual and group-based formats, as well as those with normal and more intensified approaches, were found to have an effect on PTSD.
AN  - 39878598
AU  - Nahlen
AU  - Bose,
AU  - C.
AU  - Tamdjidi,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.7146/torture.v34i3.143968
L1  - internal-pdf://3963825643/Nahlen Bose-2024-Children who survive torture_.pdf
PY  - 2024
SP  - 15-40
T2  - Torture
TI  - Children who survive torture: A systematic review of screening, documentation and treatment of torture injuries in children
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.7146%2ftorture.v34i3.143968
UR  - https://tidsskrift.dk/torture-journal/article/download/143968/195102
VL  - 34
ER  -
TY  - JOUR
AB  - There is growing use of primary prevention interventions which aim to tackle adolescent relationship abuse (ARA) through raising awareness of the issue, changing attitudes that underpin abusive behaviors, increasing knowledge and skills to promote help-seeking, and to ultimately lower the incidence of ARA victimization and perpetration. To date, several reviews have explored the effectiveness of existing ARA prevention programs. However, the reviews often focus on a single type of intervention, setting, and/or condition, making identifying, summarizing, and appraising the available evidence challenging. Meaning it can be difficult to ascertain what works for whom and under what circumstances. Therefore, this umbrella review provides an up-to-date resynthesis and re-analysis of reviews of the ARA prevention literature, culminating in a comprehensive summary of the efficacy of program content, design, delivery, and evaluation. A systematic search of seven crossdisciplinary databases yielded 21 reviews and meta-analyses reporting the effectiveness of school-based ARA prevention programs, published prior to June 2023. This review examined review objectives, program characteristics (e.g., sample size and features, implementer details), outcome measures and findings and reported 11 determinants associated with intervention success. The findings revealed critical gaps regarding &#039;what works&#039; for school-based ARA primary prevention intervention, resulting in a set of recommendations for future program optimization.
AN  - WOS:001219059900001
AU  - Sheng,
AU  - X.
AU  - M.
AU  - Miller,
AU  - P.
AU  - Gomersall,
AU  - T.
AU  - Wager,
AU  - N.
DB  - Juni 24.enl
DO  - 10.1016/j.avb.2024.101942
L1  - internal-pdf://4197477954/1-s2.0-S1359178924000326-main.cleaned.pdf
PY  - 2024
SP  - 17
T2  - Aggression and Violent Behavior
TI  - School-based primary prevention interventions for adolescent relationship abuse: An umbrella review
UR  - &lt;Go to ISI&gt;://WOS:001219059900001
VL  - 77
ER  -
TY  - JOUR
AB  - **Background**: Understanding how development influences medication and placebo responses in anxiety disorders could inform treatment decisions, including age-specific first- versus second-line psychopharmacological interventions. **Objective**: To meta-analytically compare the trajectory of selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and placebo response in youth and adults with anxiety disorders. **Methods**: Weekly symptom severity data were extracted from prospective, randomized, parallel-group, placebo-controlled trials of SSRIs and SNRIs in children, adolescents, and adults with anxiety disorders (generalized, separation, and social anxiety disorders as well as panic disorder). Treatment response was modeled for the standardized change in continuous measures of anxiety using a Bayesian hierarchical model. Change in symptom severity was evaluated as a function of time, and post hoc analyses were conducted to determine the sensitivity of these results across sample heterogeneity and alternative functional forms. **Results**: Data were included from 11 trials of youth (SSRI, kappa = 7; SNRI, kappa = 4) and 71 studies of adults (SSRI, kappa = 46; SNRI, kappa = 25). In total, 1067 youth participated in SSRI trials and 1024 in SNRI trials. In total, 10,826 adults participated in SSRI trials (placebo, n = 5367; SSRI n = 5,459) and 6232 in SNRI trials (placebo, n = 3,128; SNRI n = 3,094). A logarithmic model best described the response. Placebo response was similar in youth and adults (mean difference = -1.98 +/- 6.21, 95% credible interval [CrI]: -10.2 to 14.2, p = 0.750), and statistically significant improvement from baseline emerged by week 2 in both adults (mean difference: -18.34 + 1.017, 95% CrI: -20.3 to 16.3, p &lt; 0.001) and youth (mean difference: -23.74 + 3.736, 95% CrI: -31.1 to -16.4, p &lt; 0.001). SSRIs produced similar improvements for youth and adults (p = 0.129), but SNRIs produced slower improvement in youth than adults (p = 0.018). **Conclusions**: Antidepressant-related improvement occurs early in youth and adults with anxiety disorders. SSRI response is similar in adults and youth; however, SNRIs produce greater responses in adults than youth, potentially representing a developmental effect.
AN  - 38800869
AU  - Mills,
AU  - J.
AU  - A.
AU  - Mendez,
AU  - E.
AU  - Strawn,
AU  - J.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1089/cap.2024.0016
L1  - internal-pdf://2280860085/dff04092-076f-4da8-9a66-5d2577f3441c.pdf
PY  - 2024
SP  - 302-309
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - The Impact of Development on Antidepressant and Placebo Response in Anxiety Disorders: A Bayesian Hierarchical Meta-Analytic Examination of Randomized Controlled Trials in Children, Adolescents, and Adults
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1089%2fcap.2024.0016
UR  - https://www.liebertpub.com/doi/10.1089/cap.2024.0016
VL  - 34
ER  -
TY  - JOUR
AB  - Growing evidence indicates that family-based mind-body therapy programs (FMBTs) act as an important alternative for attention-deficit/hyperactivity disorder (ADHD) treatment in the youth with minimal side-effects. Moreover, FMBTs contribute to improving the family functioning of those affected by ADHD. To summarize and analyze the benefits and mechanisms, an extensive literature search of the EBSCOhost, PubMed, Web of Science, and Scopus databases was conducted to identify eligible studies. Fifteen studies published between 2010-2023 were reviewed. The included FMBTs were implemented with 850 children/adolescents and 996 parents/caregivers, of whom 201 parent couples attended the programs together with their children. All included FMBTs adopted mindfulness/meditation as the core practice to enhance the participants&#039; mental focus and attention, and were designed for long-term engagement, with six including parent-child joint session(s). Positive changes were observed in both children and adolescents, including improvements in ADHD symptoms, behavioral problems, executive function, and school performance. Additionally, parents experienced positive changes in ADHD traits/symptoms, mental health, and parenting behaviors. Furthermore, FMBTs were found to enhance family functioning by delivering mindful strategies to family, restoring psychological capacity and interpersonal skills in family members, and improving parent-child relationships. The reviewed FMBTs demonstrated high levels of feasibility and participant satisfaction. The factors and issues potentially influencing the effectiveness and feasibility of FMBTs are also discussed. The findings indicate that FMBT holds promise as an ADHD treatment option in home settings. Future efforts may focus on optimizing the design of FMBTs to better address the diverse needs of families in varying circumstances.
AN  - WOS:001187109500001
AU  - Fang,
AU  - Y.
AU  - Liu,
AU  - J.
AU  - Zhang,
AU  - B.
AU  - R.
AU  - Lau,
AU  - M.
AU  - Ho,
AU  - Y.
AU  - F.
AU  - Yang,
AU  - Y.
AU  - X.
AU  - Shi,
AU  - Y.
AU  - Poon,
AU  - E.
AU  - T.
AU  - C.
AU  - Tse,
AU  - A.
AU  - C.
AU  - Y.
AU  - Sun,
AU  - F.
AU  - H.
DB  - April 24.enl
DO  - 10.1177/02654075241239878
L1  - internal-pdf://4113328206/fang-et-al-2024-a-systematic-review-of-the-ben.pdf
PY  - 2024
SP  - 32
T2  - Journal of Social and Personal Relationships
TI  - A systematic review of the benefits and mechanisms of family-based mind-body therapy programs targeting families of children and adolescents with attention-deficit/hyperactivity disorder
UR  - &lt;Go to ISI&gt;://WOS:001187109500001
ER  -
TY  - JOUR
AB  - **Background**: Docosahexaenoic acid (DHA) plays a crucial role in the growth and functional development of the infant brain. However, the impact of additional DHA supplementation on neurodevelopment in infants remains controversial in randomized controlled trials. In this systematic review and meta-analysis, we aimed to investigate the effects of prenatal and postnatal DHA supplementation on neurodevelopment. 

**Methods**: We systematically searched the MEDLINE, EMBASE, and Cochrane Library electronic databases using a predefined strategy until 8 February 2024. We extracted relevant study characteristics and outcomes related to the nervous system. Two independent reviewers critically evaluated the included studies to assess their validity and risk of bias. 

**Results**: A total of 21 studies met our inclusion criteria, one study was removed after quality assessment, and the meta-analysis included 9 randomized controlled trials. The meta-analysis results indicated that there was no statistically significant difference between the DHA supplementation group and the placebo group, as assessed by the Mental Development Index [MDI; mean difference (MD), 0.41; 95% confidence interval (CI), -0.91 to 1.73; p = 0.55]. However, the DHA group had a significantly higher Psychomotor Development Index (PDI) than the placebo group (MD, 1.47; 95% CI, 0.23 to 2.72; p = 0.02). Subgroup analyses based on populations showed that DHA supplementation was superior to placebo for infants in both MDI (language score conversion; MD, 2.05; 95% CI, -0.16 to 4.26; p = 0.07) and PDI (MD, 1.94; 95% CI, 0.23 to 3.65; p = 0.03). Other subgroup analyses indicated no statistical differences between the two groups. The remaining assessments that could not be summarized quantitatively underwent a narrative evaluation. 

**Conclusion**: Based on the BSID assessments, DHA supplementation in infants may have potential neurodevelopmental benefits. Because the meta-analysis included few high-quality articles and had some limitations, more relevant articles are needed to address the need for separate DHA supplementation in infants, pregnant women, and lactating mothers. 

**Systematic review registration**: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022348100, identifier: CRD42022348100.
AN  - 38645744
AU  - Hu,
AU  - R.
AU  - Xu,
AU  - J.
AU  - Hua,
AU  - Y.
AU  - Li,
AU  - Y.
AU  - Li,
AU  - J.
DB  - April 24.enl
DO  - /10.3389/fneur.2024.1295788
L1  - internal-pdf://2108530648/Hu-2024-Could early life DHA supplementation b.pdf
PY  - 2024
SP  - 1295788
T2  - Frontiers in neurology [electronic resource].
TI  - Could early life DHA supplementation benefit neurodevelopment? A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffneur.2024.1295788
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11032049/pdf/fneur-15-1295788.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Background and Aim: Pharmacotherapeutic options for attention-deficit hyperactivity disorder (ADHD) are limited due to adverse effects and inadequate efficacy of existing drugs. Clinical trials were conducted on dasotraline in search of a safer and more efficacious alternatives to stimulant agents. This meta-analysis was conducted to evaluate the efficacy and safety of dasotraline in ADHD compared to placebo. 

Methods: The reviewers extracted data from five relevant clinical trials after a literature search on Medline/PubMed, Embase, Scopus, Google Scholar, and Cochrane databases and Clinical Trial Registries. Quality assessment was done using the risk of bias assessment tool, and the random-effects model was used to estimate the effect size. Sub-group analysis, meta-regression, and sensitivity analysis were done as applicable. PRISMA guidelines were followed in the selection, analysis, and reporting of findings. 

Results: Dasotraline significantly reduced the ADHD total symptom score (SMD: -0.35; 95% CI: -0.55 to -0.15; P &lt; 0.001), hyperactivity/impulsivity subscale score (SMD: -0.27; 95% CI: -0.44 to -0.11; P = 0.001), inattentiveness sub-scale score (SMD: -0.33; 95% CI: -0.53 to -0.14; P &lt; 0.001), and CGI-S (SMD: -0.25; 95% CI: -0.42 to -0.08; P = 0.003). Sub-group analysis showed a significant reduction of ADHD symptoms in both pediatric and adult age groups. Meta-regression showed a significant association between SMD of ADHD symptom score reduction and the duration of dasotraline therapy. The incidence of decreased appetite showed dose dependence but not the incidence of insomnia.

Conclusions: Dasotraline 4 mg (in children) and 6 mg (in adults) can improve the clinical outcome in patients with ADHD by improving symptoms and global functioning with acceptable tolerability.PROSPERO Registration number: CRD42022321979.
AN  - 38778858
AU  - Maiti,
AU  - R.
AU  - Mishra,
AU  - A.
AU  - Jena,
AU  - M.
AU  - Maji,
AU  - S.
AU  - Padhan,
AU  - M.
AU  - Mishra,
AU  - B.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.4103/indianjpsychiatry.indianjpsychiatry_3_24
L1  - internal-pdf://4246232760/efficacy_and_safety_of_dasotraline_in.2.pdf
PY  - 2024
SP  - 326-335
T2  - Indian Journal of Psychiatry
TI  - Efficacy and safety of dasotraline in attention-deficit hyperactivity disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.4103%2findianjpsychiatry.indianjpsychiatry_3_24
VL  - 66
ER  -
TY  - JOUR
AB  - Background: This study aimed to explore the effects of physical activity (PA) on motor skills and stereotypical behavior in children with autism spectrum disorder (ASD). 

Methods: Studies were searched in PubMed, Web of Science, Embase, the Cochrane Library, and CNKI. A total of 14 studies with 345 participants were included in this study, and a randomeffects model with the standard mean difference (SMD) was used to calculate the effect size. We include 6 scales to evaluate motor skills and 2 scales to evaluate stereotyped behavior. 

Results: Compared with the baseline, the PA group showed a significantly improved Test of Gross Motor Skills (TGMD) [SMD = 1.90 (95%CI: 0.78 to 3.02), p &lt; 0.001] and Brininx-Oresetsky Test (BOT) [SMD = 7.37 (95%CI: 1.72 to 13.02), p = 0.01], while the control group did not significantly change in TGMD. For stereotyped behavior, there was a significant reduction in GARS-2 [SMD = -0.64 (95%CI: -1.10 to -0.18), p = 0.01] in the PA group compared with the baseline, while the control group did not significantly change. 

Conclusion: This meta-analysis confirmed the beneficial effects of PA on motor skills and stereotyped behavior in children with ASD. Engaging in activities like ball games at moderate intensity can be beneficial. Further research should examine the specific effects of various PA types and intensities to enhance PA-based interventions for ASD.
AN  - WOS:001239454100001
AU  - Jiang,
AU  - J.
AU  - Y.
AU  - Wang,
AU  - G.
AU  - X.
AU  - Gu,
AU  - Q.
AU  - W.
AU  - Wang,
AU  - X.
AU  - Liu,
AU  - J.
AU  - X.
DB  - Juni 24.enl
DO  - 10.1016/j.rasd.2024.102395
L1  - internal-pdf://2484563163/1-s2.0-S1750946724000709-main.cleaned.pdf
PY  - 2024
SP  - 13
T2  - Research in Autism Spectrum Disorders
TI  - Quantifying the efficacy of physical activity on motor skills and stereotypies in children with autism spectrum disorder: A meta-analysis of randomized controlled trials from the last decade
UR  - &lt;Go to ISI&gt;://WOS:001239454100001
VL  - 114
ER  -
TY  - JOUR
AB  - OBJECTIVE: To investigate the influence of aerobic exercise on depression among the young people. 

DATA SOURCES: PubMed, Web of science, Embase, Cochrane, EBSCO were searched from inception to November 2023. 

STUDY SELECTION: RCT studies, assessing the use of aerobic exercise in young people aged 6-35 years and then determining the development of depression in young people (aged 6-35 years), were selected, and mean +/- SD values adjusted for the presence of baseline depression were extracted. 

DATA EXTRACTION AND SYNTHESIS: Study quality was assessed using the Review manager 5.4.1 and Cochrane 5.1 item on risk of bias and precision of observational studies. Two reviewers conducted all review stages independently. Selected data were pooled using random-effects meta-analysis.

MAIN OUTCOMES AND MEASURES: The included studies evaluated the relationship between aerobic exercise and depression at various time points among young individuals, and provided corresponding mean +/- SD values. Depression diagnosis in the selected studies was conducted using the Depression Correlation Scale.

RESULTS: After screening 2296 articles, 163 articles were selected for full-text review, and 8 of those were further reviewed. Ultimately, 12 studies, involving 658 individuals, were included in the meta-analysis. The results of the meta-analysis indicated that aerobic exercise could effectively improve depression in young people (d = -1.33, 95%CI: -1.78 ~ -0.87, P &lt; 0.05). Subgroup analysis demonstrated that aerobic exercise was beneficial for both depression (d = -2.68, 95%CI: -3.87 ~ -1.48, P &lt; 0.05) and non-depression (d = -0.85, 95%CI: -1.20 ~ -0.51, P &lt; 0.05) conditions, as well as for low intensity (d = -0.93, 95%CI: -1.29 ~ 0.58, P &lt; 0.05) and moderate intensity (d = -2.08,95%CI:-2.88 ~ -1.27, P &lt; 0.05) exercises. Additionally, aerobic exercise was found to significantly alleviate depression in young people when performed for 40 min or less (d = -2.00,95%CI: -2.96 ~ -1.04, P &lt; 0.05), whereas durations exceeding 40 min showed a lesser effect (d = -0.85,95%CI:-1.47 ~ -0.24, P &lt; 0.05). Furthermore, the duration-based analysis revealed that aerobic exercise improved depression levels in young people regardless of duration, whether it was for less than 6 weeks (d = -1.27,95%CI: 2.12 ~ 0.14, P &lt; 0.05), 6 to 11 weeks (d = 1.55, 95% CI: 2.16 ~ 0.94, P &lt; 0.05), or more than 12 weeks (d = 1.00, 95% CI: -1.76 ~ -0.24,P &lt; 0.05). Overall, these findings suggest that aerobic exercise is a promising intervention for alleviating depression in young individuals. 

CONCLUSIONS: Both short (less than 40 min) and long (more than 40 min) periods of aerobic exercise were effective in improving depressive symptoms. However, the optimal duration of aerobic exercise may vary depending on the specific population and individual factors studied, such as age, health status, and exercise tolerance. Therefore, this study concluded that the most effective exercise regimen, 40 min of moderate-intensity aerobic exercise three times a week for 6 to 11 weeks, showed more significant improvement in depression indicators in individuals with depressive symptoms.
AN  - 39164715
AU  - Li,
AU  - W.
AU  - Liu,
AU  - Y.
AU  - Deng,
AU  - J.
AU  - Wang,
AU  - T.
DB  - August 2024.enl
DO  - /10.1186/s12888-024-06013-6
L1  - internal-pdf://0510680856/Li-2024-Influence of aerobic exercise on depre.pdf
PY  - 2024
SP  - 571
T2  - BMC Psychiatry
TI  - Influence of aerobic exercise on depression in young people: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1186%2fs12888-024-06013-6
UR  - https://bmcpsychiatry.biomedcentral.com/counter/pdf/10.1186/s12888-024-06013-6.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - Anxiety and obsessive-compulsive disorders have a significant negative impact on youth. Cognitive behavioural therapy (CBT) is recommended and established as effective first-step treatment, but persistent symptoms and non-response are common. Intensive psychological treatments deliver more or longer sessions over a shorter time span, with fewer session gaps. However, an understanding of their effectiveness, characteristics, acceptability, and feasibility is lacking. Systematically searching five databases yielded four controlled and 36 uncontrolled studies (N=2707) involving youth with primary anxiety or obsessive-compulsive disorders, many of whom received prior treatments. Intensive treatments were acceptable and feasible, with low drop-out rates. Betweengroup analyses compared intensive treatment with standard treatment (k = 2) or waitlist (k = 2), revealing no significant post-treatment differences in symptom severity or remission. Uncontrolled within-group analyses of intensive treatments showed large improvements from pre- to post-treatment in symptoms (k = 47), remission (k = 17), impairment (k = 22), functioning (k = 5), and quality of life (k = 2), with larger effects at follow-ups. Intensive treatments show promise for youth with anxiety or obsessive-compulsive disorders by potentially offering high treatment completion rates and comparable outcomes to standard CBT, aiding earlier recovery and reducing overall suffering. This systematic review/meta-analysis provides a comprehensive overview of intensive treatments, their theoretical considerations, and empirical findings. Future RCTs should compare the effectiveness of standard and intensive treatments and identify optimal populations for their use.
AN  - WOS:001355930800001
AU  - Ganzevoort,
AU  - C.
AU  - O.
AU  - W.
AU  - Wolters,
AU  - L.
AU  - H.
AU  - Hornstra,
AU  - R.
AU  - Grieve,
AU  - C.
AU  - M.
AU  - Hojgaard,
AU  - Drma
AU  - Skarphedinsson,
AU  - G.
AU  - A.
AU  - Weidle,
AU  - B.
AU  - Waite,
AU  - P.
AU  - Bertie,
AU  - L.
AU  - A.
AU  - Tomlinson,
AU  - M.
AU  - Nauta,
AU  - M.
AU  - H.
DB  - November 2024.enl
DO  - 10.1016/j.janxdis.2024.102940
L1  - internal-pdf://2807332723/1-s2.0-S0887618524001166-main.pdf
internal-pdf://1496219507/Intensive treatments for children and adolesce.pdf
PY  - 2024
SP  - 39
T2  - Journal of Anxiety Disorders
TI  - Intensive treatments for children and adolescents with anxiety or obsessive-compulsive disorders: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001355930800001
UR  - https://www.sciencedirect.com/science/article/pii/S0887618524001166?pes=vor&amp;utm_source=clarivate&amp;getft_integrator=clarivate
VL  - 108
ER  -
TY  - JOUR
AB  - **BACKGROUND**: 
The degree of physiological responses to individual antipsychotic drugs is unclear in children and adolescents. With network meta-analysis, we aimed to investigate the effects of various antipsychotic medications on physiological variables in children and adolescents with neuropsychiatric and neurodevelopmental conditions. 

**METHODS**:
 For this network meta-analysis, we searched Medline, EMBASE, PsycINFO, Web of Science, and Scopus from database inception until Dec 22, 2023, and included randomised controlled trials comparing antipsychotics with placebo in children or adolescents younger than 18 years with any neuropsychiatric and neurodevelopmental condition. Primary outcomes were mean change from baseline to end of acute treatment in bodyweight, BMI, fasting glucose, total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, prolactin, heart rate, systolic blood pressure (SBP), and QT interval corrected for heart rate (QTc) for patients receiving either active treatment or placebo. For multigroup trials reporting several doses, we calculated a summary value for each physiological variable for all doses. After transitivity assessment, we fitted frequentist random-effects network meta-analyses for all comparisons in the network. A Kilim plot was used to summarise the results for all treatments and outcomes, providing information regarding the strength of the statistical evidence of treatment effects, using p values. Network heterogeneity was assessed with tau, risk of bias of individual trials was assessed with the Cochrane Collaboration&#039;s Tool for Assessing Risk of Bias, and the credibility of findings from each network meta-analysis was assessed with the Confidence in Network Meta-Analysis (CINEMA) app. This study is registered on PROSPERO (CRD42021274393). 

**FINDINGS**:
 Of 6676 studies screened, 47 randomised controlled trials were included, which included 6500 children (mean age 13.29 years, SD 2.14) who received treatment for a median of 7 weeks (IQR 6-8) with either placebo (n=2134) or one of aripiprazole, asenapine, blonanserin, clozapine, haloperidol, lurasidone, molindone, olanzapine, paliperidone, pimozide, quetiapine, risperidone, or ziprasidone (n=4366). Mean differences for bodyweight change gain compared with placebo ranged from -2.00 kg (95% CI -3.61 to -0.39) with molindone to 5.60 kg (0.27 to 10.94) with haloperidol; BMI -0.70 kg/m&lt;sup&gt;2&lt;/sup&gt; (-1.21 to -0.19) with molindone to 2.03 kg/m&lt;sup&gt;2&lt;/sup&gt; (0.51 to 3.55) with quetiapine; total cholesterol -0.04 mmol/L (-0.39 to 0.31) with blonanserin to 0.35 mmol/L (0.17 to 0.53) with quetiapine; LDL cholesterol -0.12 mmol/L (-0.31 to 0.07) with risperidone or paliperidone to 0.17 mmol/L (-0.06 to 0.40) with olanzapine; HDL cholesterol 0.05 mmol/L (-0.19 to 0.30) with quetiapine to 0.48 mmol/L (0.18 to 0.78) with risperidone or paliperidone; triglycerides -0.03 mmol/L (-0.12 to 0.06) with lurasidone to 0.29 mmol/L (0.14 to 0.44) with olanzapine; fasting glucose from -0.09 mmol/L (-1.45 to 1.28) with blonanserin to 0.74 mmol/L (0.04 to 1.43) with quetiapine; prolactin from -2.83 ng/mL (-8.42 to 2.75) with aripiprazole to 26.40 ng/mL (21.13 to 31.67) with risperidone or paliperidone; heart rate from -0.20 bpm (-8.11 to 7.71) with ziprasidone to 12.42 bpm (3.83 to 21.01) with quetiapine; SBP from -3.40 mm Hg (-6.25 to -0.55) with ziprasidone to 10.04 mm Hg (5.56 to 14.51) with quetiapine; QTc from -0.61 ms (-1.47 to 0.26) with pimozide to 0.30 ms (-0.05 to 0.65) with ziprasidone. 

**INTERPRETATION**: Children and adolescents show varied but clinically significant physiological responses to individual antipsychotic drugs. Treatment guidelines for children and adolescents with a range of neuropsychiatric and neurodevelopmental conditions should be updated to reflect each antipsychotic drug&#039;s distinct profile for associated metabolic changes, alterations in prolactin, and haemodynamic alterations. <b>FUNDING</b>: UK Academy of Medical Sciences, Brain and Behaviour Research Foundation, UK National Institute of Health Research, Maudsley Charity, the Wellcome Trust, Medical Research Council, National Institute of Health and Care Research Biomedical Centre at King&#039;s College London and South London and Maudsley NHS Foundation Trust, the Italian Ministry of University and Research, the Italian National Recovery and Resilience Plan, and Swiss National Science Foundation.
AN  - 38897716
AU  - Rogdaki,
AU  - M.
AU  - McCutcheon,
AU  - R.
AU  - A.
AU  - D&#039;Ambrosio,
AU  - E.
AU  - Mancini,
AU  - V.
AU  - Watson,
AU  - C.
AU  - J.
AU  - Fanshawe,
AU  - J.
AU  - B.
AU  - Carr,
AU  - R.
AU  - Telesia,
AU  - L.
AU  - Martini,
AU  - M.
AU  - G.
AU  - Philip,
AU  - A.
AU  - Gilbert,
AU  - B.
AU  - J.
AU  - Salazar-de-Pablo,
AU  - G.
AU  - Kyriakopoulos,
AU  - M.
AU  - Siskind,
AU  - D.
AU  - Correll,
AU  - C.
AU  - U.
AU  - Cipriani,
AU  - A.
AU  - Efthimiou,
AU  - O.
AU  - Howes,
AU  - O.
AU  - D.
AU  - Pillinger,
AU  - T.
DB  - Juni 24.enl
DO  - /10.1016/S2352-4642(24)00098-1
L1  - internal-pdf://4018236291/1-s2.0-S2352464224000981-main.cleaned.pdf
PY  - 2024
SP  - 510-521
T2  - The Lancet Child &amp; Adolescent Health
TI  - Comparative physiological effects of antipsychotic drugs in children and young people: a network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1016%2fS2352-4642%2824%2900098-1
VL  - 8
ER  -
TY  - JOUR
AB  - Tic disorders (TDs) are neurodevelopmental conditions which affect 0.3-0.9% of individuals aged &lt; 18 years. Although tics often improve or resolve spontaneously over time, treatment is often recommended. Pharmacological approaches are widely used as primary interventions. However, their side effects encouraged the development and the interest in nonpharmacological approaches, whose efficacy in pediatric populations remains poorly understood. This systematic review aimed to evaluate the efficacy of nonpharmacological treatments for children and adolescents with TDs. A literature review was performed using PubMed, EBSCOhost, and JABA databases up to 16 May 2024. Eligible articles were randomized controlled trials, written in English and published in peer-reviewed journals, investigating the efficacy of nonpharmacological treatments in pediatric populations diagnosed with TDs. Significant evidence supported the efficacy of behavioral interventions such as the Comprehensive Behavioral Intervention for Tics (CBIT), its reduced version the Habit Reversal Therapy (HRT), and the Exposure and Relapse Prevention (ERP) in reducing tics and tic-related impairment among young people, as assessed through the Yale Global Tic Severity Scale. Behavioral interventions were generally effective in reducing tics, although some studies reported higher effects on motor tics when compared to vocal tics. High level of efficacy was observed for both face-to-face and online treatments. While future studies are needed to improve treatment effects, especially on vocal tics, as well as to have a better understanding of treatment components and modalities, taken together, the present findings support the use of nonpharmacological intervention for TDs in youth.
AN  - WOS:001342626000001
AU  - Amico,
AU  - C.
AU  - Crepaldi,
AU  - C.
AU  - Rinaldi,
AU  - M.
AU  - Buffone,
AU  - E.
AU  - Scaini,
AU  - S.
AU  - Forresi,
AU  - B.
AU  - Leoni,
AU  - M.
DB  - November 2024.enl
DO  - 10.3390/app14209466
L1  - internal-pdf://3093069558/Amico-2024-Efficacy of Nonpharmacological Trea.pdf
PY  - 2024
SP  - 18
T2  - Applied Sciences-Basel
TI  - Efficacy of Nonpharmacological Treatment in Children and Adolescent with Tic Disorder: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001342626000001
UR  - https://mdpi-res.com/d_attachment/applsci/applsci-14-09466/article_deploy/applsci-14-09466-v2.pdf?version=1729754701
VL  - 14
ER  -
TY  - JOUR
AB  - Autism Spectrum Disorder (ASD) is a complex neurological condition that significantly impacts individuals&#039; daily lives and social interactions due to challenges in verbal and non-verbal communication. Game-based tools for psychological support and patient education are rapidly gaining traction. Among these tools, teaching social skills via serious games has emerged as a particularly promising educational strategy for addressing specific characteristics associated with autism. Unlike traditional games, serious games are designed with a dual purpose: to entertain and to fulfill a specific educational or therapeutic goal. This systematic review aims to identify and categorize serious computer games that have been used to teach social skills to autistic individuals and to assess their effectiveness. We conducted a comprehensive search across seven databases, resulting in the identification and analysis of 25 games within 26 studies. Out of the 104 criteria assessed across these studies, 57 demonstrated significant improvement in participants. Furthermore, 22 of these studies reported significant enhancements in at least one measured criterion, with 13 studies observing significant improvements in all assessed outcomes. These findings overwhelmingly support the positive impact of computer-based serious game interventions in teaching social skills to autistic individuals.
AN  - WOS:001229663100001
AU  - Azadboni,
AU  - T.
AU  - T.
AU  - Nasiri,
AU  - S.
AU  - Khenarinezhad,
AU  - S.
AU  - Sadoughi,
AU  - F.
DB  - Juni 24.enl
DO  - 10.1016/j.neubiorev.2024.105634
L1  - internal-pdf://3060297126/1-s2.0-S0149763424001039-main.cleaned.pdf
PY  - 2024
SP  - 43
T2  - Neuroscience and Biobehavioral Reviews
TI  - Effectiveness of serious games in social skills training to autistic individuals: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:001229663100001
VL  - 161
ER  -
TY  - JOUR
AB  - **Background**
Young people who enter the justice system experience complex health and social needs, and offending behaviour is increasingly recognised as a public health problem. Arts interventions can be used with the aim of preventing or reducing offending or reoffending.

**Objectives**
1. To evaluate evidence on the effectiveness and impact of arts interventions on keeping children and young people safe from involvement in violence and crime. 2. To explore factors impacting the implementation of arts interventions, and barriers and facilitators to participation and achievement of intended outcomes. 3. To develop a logic model of the processes by which arts interventions might work in preventing offending behaviours.

**Search Methods**
We searched AMED, Academic Search Complete; APA PsycInfo; CINAHL Plus; ERIC; SocIndex; SportDiscus, Medline, CENTRAL, Web of Science, Scopus, PTSDPubs and Performing Arts Periodicals Database, Sage, the US National Criminal Justice Reference Service, the Global Policing and British Library EThOS databases, and the National Police Library from inception to January 2023 without language restrictions.

**Selection Criteria**
We included randomised and non-randomised controlled trials and quasi-experimental study designs. We included qualitative studies conducted alongside intervention trials investigating experiences and perceptions of participants, and offering insight into the barriers and facilitators to delivering and receiving arts interventions. We included qualitative and mixed methods studies focused on delivery of arts interventions. We included studies from any global setting. We included studies with CYP (8&ndash;25 years) who were identified as at-risk of offending behaviour (secondary populations) or already in the criminal justice system (tertiary populations). We included studies of interventions involving arts participation as an intervention on its own or alongside other interventions. Primary outcomes were: (i) offending behaviour and (ii) anti-pro-social behaviours. Secondary outcomes were: participation/attendance at arts interventions, educational attainment, school attendance and engagement and exclusions, workplace engagement, wellbeing, costs and associated economic outcomes and adverse events.

**Data Collection and Analysis**
We included 43 studies (3 quantitative, 38 qualitative and 2 mixed methods). We used standard methodological procedures expected by The Campbell Collaboration. We used GRADE and GRADE CERQual to assess the certainty of and confidence in the evidence for quantitative and qualitative data respectively.

**Main Results**
We found insufficient evidence from quantitative studies to support or refute the effectiveness of arts interventions for CYP at-risk of or who have offended for any outcome. Qualitative evidence suggested that arts interventions may lead to positive emotions, the development of a sense of self, successful engagement in creative practices, and development of positive personal relationships. Arts interventions may need accessible and flexible delivery and are likely to be engaging if they have support from staff, family and community members, are delivered by professional artists, involve culturally relevant activity, a youth focus, regularity and a sustainable strategy. We found limited evidence that a lack of advocacy, low funding, insufficient wider support from key personnel in adjacent services could act as barriers to success. Methodological limitations resulted in a judgement of very low confidence in these findings.

**Authors&#039; Conclusions**
We found insufficient evidence from quantitative studies to support or refute the effectiveness of arts interventions for CYP at-risk of offending or who have offended for any outcome. We report very low confidence about the evidence for understanding the processes influencing the successful design and delivery of arts interventions in this population of CYP and their impact on behavioural, psychosocial, cognitive and offending outcomes.
AU  - Mansfield,
AU  - L.,
AU  - Daykin,
AU  - N.,
AU  - O&#039;Connell,
AU  - N.
AU  - E.,
AU  - Bailey,
AU  - D.,
AU  - Forde,
AU  - L.,
AU  - Smith,
AU  - R.,
AU  - Gifford,
AU  - J.,
AU  - Ashdown-Franks,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1002/cl2.1377
L1  - internal-pdf://1782394843/Campbell Systematic Reviews - 2024 - Mansfield.pdf
PY  - 2024
T2  - Campbell Systematic Reviews
TI  - A mixed methods systematic review on the effects of arts interventions for children and young people at-risk of offending, or who have offended on behavioural, psychosocial, cognitive and offending outcomes: A systematic review
ER  -
TY  - JOUR
AB  - **Background**
Observational studies in preterm newborns suggest that delay in administering amino acids (AA) could result in a protein catabolic state and impact on growth and development.

**Objectives**
The objective of this review was to compare the efficacy and safety of early versus late administration of intravenous AA in neonates born at &lt; 37 weeks of gestation.

**Search methods**
We searched CENTRAL, MEDLINE, Embase, and trial registries in March 2023. We checked the reference lists of included studies and studies/systematic reviews where subject matter related to the intervention or population examined in this review.

**Selection criteria**
We included randomised controlled trials (RCTs) comparing early administration of AA with late administration in premature newborn infants. We defined early administration of AA solution as the administration of AA in isolation or with total parenteral nutrition within the first 24 hours of birth, and late administration as the administration of AA in isolation or with total parenteral nutrition after the first 24 hours of birth.

**Data collection and analysis**
We used standard Cochrane methodological procedures. We used the GRADE approach to assess the certainty of the evidence.

**Main results**
Nine studies (383 participants) were eligible for inclusion in the review. All study participants were born at &lt; 37 weeks of gestation and were inpatients in neonatal intensive care units.

No studies reported growth during the first months of life as assessed by difference in weight. Early administration of AA may have little or no effect on growth in the first month of life as measured by length (mean difference (MD) 0.00, 95% confidence interval (CI) &minus;0.41 to 0.41; 1 study; 21 participants; low‐certainty evidence) and head circumference (MD 0.05, 95% CI &minus;0.03 to 0.14; 2 studies; 87 participants; low‐certainty evidence). No studies reported the discharge weight outcome. Early administration of AA may result in little to no difference in neurodevelopmental outcome assessed by Mental Developmental Index (MDI) of &lt; 70 at two years of age (odds ratio 0.83, 95% CI 0.21 to 3.28; 1 study; 111 participants; low‐certainty evidence). No studies reported all‐cause mortality at 28 days and before discharge.

Early administration of AA may result in a large increase in positive nitrogen balance in the first three days of life (MD 250.42, 95% CI 224.91 to 275.93; 4 studies; 93 participants; low‐certainty evidence).

**Authors&#039; conclusions**
Low‐certainty evidence suggests that there may be little to no difference between early and late administration of AA in growth (measured by length and head circumference during the first month after birth) and neurodevelopmental outcome (assessed by MDI of &lt; 70). No RCTs reported on weight in the first month of life, mortality (all‐cause mortality at 28 days and before discharge), or discharge weight. Low‐certainty evidence suggests a large increase in positive nitrogen balance in preterm infants who received AA within 24 hours of birth. The clinical relevance of this observation is unknown.

The number of infants in the RCTs included in the review was small, and there was clinical heterogeneity amongst trials. Adequately powered trials in infants &lt; 37 weeks&#039; gestation are required to determine optimal timing of initiation of AA.

We identified two ongoing studies. Both studies will be recruiting infants &ge; 34 weeks of gestation and may or may not add to the outcome data for this review.
AN  - CD008771
AU  - Trivedi,
AU  - A.
AU  - Jatana,
AU  - V.
AU  - Sinn,
AU  - J.
AU  - K.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/14651858.CD008771.pub3
KW  - *Amino Acids
KW  - *Infant, Premature
KW  - Gestational Age
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - Nitrogen
KW  - Parenteral Nutrition
L1  - internal-pdf://0378493933/Trivedi_et_al-2024-Cochrane_Database_of_System.pdf
N1  - [Neonatal]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Early versus late administration of amino acids in preterm infants receiving parenteral nutrition
UR  - http://dx.doi.org/10.1002/14651858.CD008771.pub3
ER  -
TY  - JOUR
AB  - Objective
To systematically review and evaluate the efficacy of eating disorder focused family therapy (FT-ED) in comparison to all other forms of psychotherapy for children and adolescents with anorexia nervosa. A secondary aim is to assess the relative efficacy of different variations of FT-ED (e.g., shorter vs. longer dose, parent-focused).

Methods
A search with relevant terms was systematically conducted on four databases. Twenty-three publications across 18 randomized controlled trials met inclusion criteria. Outcomes of interest included variables related to weight, eating psychopathology, and remission status. Study quality was assessed, and data were extracted by two independent researchers.

Results
Adolescents receiving FT-ED gained significantly more weight by the end of treatment in comparison to those receiving individual psychotherapy. FT-ED that was delivered just to parents or to parents and child separately offered preferable weight outcomes and rates of recovery at the end of treatment in comparison to conjoint FT-ED. No other outcomes tested in the meta-analysis were statistically significant at the end of treatment or follow-up.

Discussion
Currently available data suggest the use of FT-ED in its conjoint or separated/parent focused format is the best outpatient treatment option for adolescents with anorexia nervosa when immediate weight gain is paramount. The variability of outcome measurement, including the tools used and timepoints chosen, limit comparison among no more than a handful of studies. The field would benefit from the standardization of measurement and reporting guidelines for future clinical trials.

Trial Registration
PROSPERO number: CRD42023396263.
AN  - 39041682
AU  - Austin,
AU  - A.
AU  - Anderson,
AU  - A.
AU  - G.
AU  - Lee,
AU  - J.
AU  - Vander
AU  - Steen,
AU  - H.
AU  - Savard,
AU  - C.
AU  - Bergmann,
AU  - C.
AU  - Singh,
AU  - M.
AU  - Devoe,
AU  - D.
AU  - Gorrell,
AU  - S.
AU  - Patten,
AU  - S.
AU  - Le
AU  - Grange,
AU  - D.
AU  - Dimitropoulos,
AU  - G.
DB  - Juli 2024.enl
DO  - /10.1002/eat.24252
L1  - internal-pdf://3891608878/Austin-2024-Efficacy of Eating Disorder Focuse.pdf
PY  - 2024
SP  - 23
T2  - International Journal of Eating Disorders
TI  - Efficacy of Eating Disorder Focused Family Therapy for Adolescents With Anorexia Nervosa: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1002%2feat.24252
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eat.24252?download=true
VL  - 23
ER  -
TY  - JOUR
AB  - BACKGROUND: The present meta-analysis investigates the efficacy of psychosocial interventions in bereaved children and adolescents. 

METHOD: We conducted a systematic review searching PsycINFO, PsycARTICLES, PubMed, MEDLINE, PSYNDEX, Web of Science, CINAHL and ERIC. Random-effects meta-analyses examined the effect of interventions on symptoms of grief, posttraumatic stress disorder (PTSD) and depression in controlled and uncontrolled studies. 

RESULTS: We included 39 studies (n = 5.578). Post-treatment, preventive interventions demonstrated a significant effect on grief (uncontrolled studies: g = 0.29, 95%CI [0.09;0.48]; controlled studies: g = 0.18, 95%CI [0.03;0.32]). For symptoms of PTSD and depression, only uncontrolled preventive studies yielded significant effects (PTSD: g = 0.24, 95%CI [0.11;0.36]; depression: g = 0.28, 95%CI [0.10;0.45]). Interventions targeting youth with increased grief-related distress demonstrated a significant effect in uncontrolled studies on grief (g = 1.25, 95%CI [0.94;1.57]), PTSD (g = 1.33, 95%CI [0.85;1.82]) and depression (g = 0.61, 95%CI [0.45;0.77]). A controlled effect size could only be calculated for PTSD symptoms (g = 0.71, 95%CI [0.15;1.27]). LIMITATIONS: Interventions varied widely, contributing to high heterogeneity. Only a small number of studies with mostly limited quality could be analysed. 

CONCLUSIONS: Psychosocial interventions may ameliorate grief symptoms in bereaved youth, especially when targeting youth with elevated grief distress. However, the effects observed in uncontrolled studies are substantially reduced when controlling for the natural course of bereavement. Given the increasing number of children worldwide bereaved through ongoing crises, research on interventions is surprisingly sparse.
AN  - 38218256
AU  - Hanauer,
AU  - C.
AU  - Telaar,
AU  - B.
AU  - Rosner,
AU  - R.
AU  - Doering,
AU  - B.
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2024.01.063
L1  - internal-pdf://3169483739/1-s2.0-S0165032724000739-main.cleaned.pdf
PY  - 2024
SP  - 164-173
T2  - Journal of Affective Disorders
TI  - The efficacy of psychosocial interventions for grief symptoms in bereaved children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38218256
UR  - https://www.sciencedirect.com/science/article/pii/S0165032724000739?via%3Dihub
VL  - 350
ER  -
TY  - JOUR
AB  - The high incidence of adolescent depression has become the focus of social and academic attention. Exercise is an important method to improve adolescent depression, but its intervention effect is still controversial. This study first compares and analyzes the relevant studies at home and abroad and finds that exercise prescription in adolescent depression intervention is not accurate enough. A meta-analysis was conducted to develop a precise exercise intervention strategy for adolescent depression. Firstly, this thesis identified how to optimize five elements (exercise intensity, exercise frequency, exercise time, exercise cycle, and exercise type) of exercise prescription to improve depression in adolescents. This is the problem. Furthermore, the concept of &quot;precision exercise&quot; was proposed, and a precision exercise intervention strategy (moderate-intensity aerobic exercise for 8-10 weeks, 3 times/week, 45-50 min/time) was constructed to improve adolescent depression. This paper also presents research that strengthens the cross-sectional research and empirical research on adolescent depression and establishes a precision exercise prescription database for adolescent depression in China. In conclusion, this study not only puts forward the concept of &quot;precision exercise&quot; but also constructs a precision exercise intervention strategy for adolescent depression, which has important theoretical and practical significance for improving the high incidence of adolescent depression.
AN  - WOS:001153362800001
AU  - Chen,
AU  - X.
AU  - H.
AU  - Zeng,
AU  - X.
AU  - Y.
AU  - Liu,
AU  - C.
AU  - Lu,
AU  - P.
AU  - C.
AU  - Shen,
AU  - Z.
AU  - M.
AU  - Yin,
AU  - R.
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/pchj.726
L1  - internal-pdf://1098191331/PsyCh Journal - 2024 - Chen - Formulation of p.pdf
PY  - 2024
SP  - 14
T2  - Psych Journal
TI  - Formulation of precise exercise intervention strategy for adolescent depression
UR  - &lt;Go to ISI&gt;://WOS:001153362800001
ER  -
TY  - JOUR
AB  - Several interventions have been developed to support families living with parental mental illness (PMI). Recent evidence suggests that programmes with whole-family components may have greater positive effects for families, thereby also reducing costs to health and social care systems. This review aimed to identify whole-family interventions, their common characteristics, effectiveness and acceptability. A systematic review was conducted according to PRISMA 2020 guidelines. A literature search was conducted in ASSIA, CINAHL, Embase, Medline, and PsycINFO in January 2021 and updated in August 2022. We double screened 3914 abstracts and 212 papers according to pre-set inclusion and exclusion criteria. The Mixed Methods Appraisal Tool was used for quality assessment. Quantitative and qualitative data were extracted and synthesised. Randomised-control trial data on child and parent mental health outcomes were analysed separately in random-effects meta-analyses. The protocol, extracted data, and meta-data are accessible via the Open Science Framework ( https://osf.io/9uxgp/ ). Data from 66 reports-based on 41 independent studies and referring to 30 different interventions-were included. Findings indicated small intervention effects for all outcomes including children&#039;s and parents&#039; mental health (d&lt;sub&gt;c&lt;/sub&gt; = -0.017, -027; d&lt;sub&gt;p&lt;/sub&gt; = -0.14, -0.16) and family outcomes. Qualitative evidence suggested that most families experienced whole-family interventions as positive, highlighting specific components as helpful, including whole-family components, speaking about mental illness, and the benefits of group settings. Our findings highlight the lack of high-quality studies. The present review fills an important gap in the literature by summarising the evidence for whole-family interventions. There is a lack of robust evidence coupled with a great need in families affected by PMI which could be addressed by whole-family interventions. We recommend the involvement of families in the further development of these interventions and their evaluation.
AN  - 38393370
AU  - Moltrecht,
AU  - B.
AU  - Lange,
AU  - A.
AU  - M.
AU  - C.
AU  - Merrick,
AU  - H.
AU  - Radley,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1007/s00787-024-02380-3
L1  - internal-pdf://2182822131/Moltrecht-2024-Whole-family programmes for fam.pdf
PY  - 2024
SP  - 23
T2  - European Child &amp; Adolescent Psychiatry
TI  - Whole-family programmes for families living with parental mental illness: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38393370
UR  - https://link.springer.com/content/pdf/10.1007/s00787-024-02380-3.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - **Objective**: Noninvasive brain stimulation (NIBS) is a promising complementary treatment for attention-deficit/hyperactivity disorder (ADHD). However, its efficacy varies due to diverse participant profiles and methodologies. This meta-analysis, registered with PROSPERO (CRD42023457269), seeks to assess NIBS efficacy in improving cognitive deficits and clinical symptoms in individuals with ADHD. **Methods**: We systematically searched five databases (October 2024) for randomized controlled trials focusing on cognitive functions and clinical symptoms in individuals meeting the DSM/ICD criteria for ADHD. A meta-analytical synthesis was conducted using RevMan 5.4.1. **Results**: Meta-analyses found significant improvement in inhibitory control, working memory, and inattention in active transcranial direct current stimulation (tDCS) groups compared with sham groups. Conversely, repetitive transcranial magnetic stimulation (rTMS) did not demonstrate significant therapeutic benefits for ADHD symptoms. Additionally, four transcranial random noise stimulation (tRNS) and three transcranial alternating current stimulation (tACS) studies demonstrated promising improvements in executive functions and the alleviation of ADHD symptoms. *Conclusions**: The findings from this meta-analysis highlight NIBS as a promising adjunctive therapy for managing ADHD, advancing both theoretical knowledge and practical treatment options in this field.
AN  - WOS:001387768900001
AU  - Yin,
AU  - Y.
AU  - Wang,
AU  - X.
AU  - K.
AU  - Feng,
AU  - T.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.3390/brainsci14121237
L1  - internal-pdf://2716114380/Yin-2024-Noninvasive Brain Stimulation for Imp.pdf
PY  - 2024
SP  - 22
T2  - Brain Sciences
TI  - Noninvasive Brain Stimulation for Improving Cognitive Deficits and Clinical Symptoms in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001387768900001
UR  - https://mdpi-res.com/d_attachment/brainsci/brainsci-14-01237/article_deploy/brainsci-14-01237.pdf?version=1733746726
VL  - 14
ER  -
TY  - JOUR
AB  - The twenty-first century has seen the development and delivery of online programs of behavioral family intervention for disruptive child behavior. Typically, programs evaluate outcomes in terms of change in child functioning and change in parenting ability. Existing research has also articulated the importance of parent-child relational capacity and its role in facilitating change in child functioning, and the importance of parent emotion regulation in the interests of ensuring optimal child development. These factors were explored in a meta-analysis of k = 14 prospective longitudinal research studies of online parenting interventions for disruptive child behavior. Peer reviewed randomized controlled trials with inactive control groups that were published in English between 2000 and 2022 were included in the review if they were delivered online; offered parent self-directed treatment; included as participants families who were screened as having child behavioral difficulties on validated psychometric assessment measures; and assessed child treatment outcomes, parenting ability and parent treatment outcomes. The protocol for this study was pre-registered with PROSPERO (CRD42020215947). Statistical analyses employed random effects models and reported pooled effect sizes (Hedge&#039;s g) within and between groups. Results emphasize the importance of child outcomes and parenting ability in program assessment, however, suggest that parents&#039; capacity to develop optimal parent-child relationships and regulate emotion may not be sufficiently reflected in program content. Identified continuous and categorical moderators of treatment outcome were also assessed. Results of the review are discussed in terms of their potential to influence the future development of online programs of behavioral family intervention and, therefore, child development.
AN  - 38613631
AU  - McAloon,
AU  - J.
AU  - Armstrong,
AU  - S.
AU  - M.
DB  - April 24.enl
DO  - /10.1007/s10567-024-00477-4
L1  - internal-pdf://2823496986/McAloon-2024-The Effects of Online Behavioral.pdf
PY  - 2024
SP  - 13
T2  - Clinical Child &amp; Family Psychology Review
TI  - The Effects of Online Behavioral Parenting Interventions on Child Outcomes, Parenting Ability and Parent Outcomes: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs10567-024-00477-4
UR  - https://link.springer.com/content/pdf/10.1007/s10567-024-00477-4.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - Acceptance and Commitment Therapy (ACT; Hayes et al., 1999) has gained evidence as an efficacious treatment for adolescent anxiety. The primary aim of this review was to evaluate research evidence about the efficacy of ACT when delivered in group-format for adolescent anxiety. The secondary aim was to undertake a subgroup analysis to assess the effect of group ACT on adolescent anxiety as a function of symptom severity. Finally, we aimed to assess the effect of group ACT on adolescent psychological inflexibility. Electronic databases PsycInfo (EBSCO); PubMed (NCBI); Scopus (Elsevier); Cochran Library; Embase (Ovid); MEDLINE (Ovid); Web of Science Core Collection (Thomson Reuters); and ProQuest Dissertation &amp; Theses were searched for prospective longitudinal research involving 10-20-year-olds. No restrictions were placed on publication date. A systematic review and Meta-Analysis was conducted on studies that met inclusion criteria. Results indicated that group ACT had significant, positive, between group&#039;s effects on anxiety symptoms in adolescents post treatment. Within group&#039;s analysis revealed reductions in anxiety symptoms in adolescents at follow up that were greater than those observed post treatment. Subgroup analysis indicated differences in efficacy depending on symptom severity, suggesting that ACT may be most effective for adolescents with clinically significant symptoms of anxiety. Finally, group ACT had significant, positive, between group&#039;s effects on psychological inflexibility post treatment. Within group&#039;s analysis also revealed reductions in psychological inflexibility in adolescents at follow up. Limited publication bias was evident across the included studies. These findings indicate that group ACT may be effective in reducing anxiety symptoms in adolescents, particularly in cases involving clinically significant symptoms characterised by psychological inflexibility. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2024-37550-001
AU  - Burley,
AU  - J.
AU  - McAloon,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jcbs.2023.11.003
L1  - internal-pdf://1079537745/1-s2.0-S2212144723001254-main.cleaned.pdf
PY  - 2024
T2  - Journal of Contextual Behavioral Science Vol 31, 2024, ArtID 100712
TI  - Group acceptance and commitment therapy for adolescent anxiety: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2024-37550-001
UR  - https://www.sciencedirect.com/science/article/pii/S2212144723001254?via%3Dihub
VL  - 31
ER  -
TY  - JOUR
AB  - The role of bystanders in bullying and cyberbullying prevention is crucial. Strategies must be tailored to address the shared and unique factors in online and offline contexts, ensuring that interventions create an environment where bystanders are empowered and feel responsible to act against bullying and cyberbullying. This meta-analysis examines and compares the effectiveness of interventions in enhancing bystander behaviors in bullying and cyberbullying scenarios. A comprehensive search was conducted using databases including PsycINFO, Medline, Sociological Abstracts, Social Service Abstracts, ERIC, and Scopus. Quasi-experimental and randomized controlled trials published before March 31, 2024 that reported that the effects of bystander interventions were included. The synthesis comprised 49 studies, reporting an overall random effect size (Cohen&#039;s d) of 0.25. The results highlight the crucial roles of enhancing knowledge, self-efficacy, and coping skills. Subgroup analysis revealed that the effective bystander interventions include smaller sample sizes (&lt;100 participants), shorter durations (&lt;1 month), targeting college students, and utilizing offline intervention approaches and digital techniques. These findings emphasize the promising effects and tailored characteristics of bystander intervention programs in bullying and cyberbullying contexts. Our review identifies avenues for future research within educational settings to develop more effective bystander behavior interventions to reduce bullying and cyberbullying.
AN  - WOS:001363239400001
AU  - Chen,
AU  - Q.
AU  - Q.
AU  - Lin,
AU  - W.
AU  - Z.
AU  - Wu,
AU  - Q.
AU  - R.
AU  - Ling,
AU  - C.
AU  - K.
DB  - Desember 2024.enl
DO  - 10.1177/15248380241297362
L1  - internal-pdf://2696869606/chen-et-al-2024-the-effectiveness-of-intervent.pdf
PY  - 2024
SP  - 17
T2  - Trauma Violence &amp; Abuse
TI  - The Effectiveness of Interventions on Bullying and Cyberbullying Bystander: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001363239400001
UR  - https://journals.sagepub.com/doi/10.1177/15248380241297362
ER  -
TY  - JOUR
AB  - Adolescents with physical disabilities experience common psychological distress that interacts with impaired physical function. While cognitive-based interventions have been implemented for adolescents with physical disabilities, their effects on enhancing psychological health remain uncertain. This systematic review aimed to synthesise the effects of cognitive-based interventions on the psychological distress of this population and identify optimal components for evidence-based interventions. Following the PRISMA guideline, nine databases were searched to identify eligible randomised controlled trials examining the effects of cognitive-based interventions for adolescents with physical disabilities from inception to October 2023. Data syntheses were performed using the R software, employing random-effects models. Twelve trials involving 1201 participants were identified. The pooled results revealed that cognitive-based interventions did not yield noticeable effects in reducing anxiety (g = -0.43 for postintervention; -0.14 for medium term; -0.37 for long term), depression (g = -0.05 for postintervention; -0.02 for medium term; -0.15 for long term) and stress levels (g = -0.15) over time. The secondary outcome (physical function) improved significantly in the long term compared to the control groups (g = 0.31). Furthermore, this review identified variations in the effectiveness of CBIs among different recipients, durations and modes of delivery. Given the limited number and overall low quality of identified studies for each outcome, conducting high-quality randomised controlled trials is recommended to validate the effectiveness of cognitive-based interventions in reducing psychological distress among adolescents with physical disabilities.
AN  - 39010290
AU  - Li,
AU  - J.
AU  - Li,
AU  - Y.
AU  - Mei,
AU  - X.
AU  - He,
AU  - H.
AU  - Yu,
AU  - L.
AU  - Ho,
AU  - G.
AU  - W.
AU  - K.
AU  - Chan,
AU  - E.
AU  - A.
DB  - Juli 2024.enl
DO  - /10.1111/inm.13391
L1  - internal-pdf://1624194756/Li-2024-Effectiveness of Cognitive-Based Inter.pdf
PY  - 2024
SP  - 15
T2  - International Journal of Mental Health Nursing
TI  - Effectiveness of Cognitive-Based Interventions on Psychological Distress in Adolescents With Physical Disabilities: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1111%2finm.13391
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/inm.13391?download=true
VL  - 15
ER  -
TY  - JOUR
AB  - **Background:** Co-design is recommended in mental health fields and has been associated with improved intervention efficacy. Despite its growing popularity, syntheses of evidence on the effectiveness of co-designed interventions are scarce, and little is known about their impact on anxiety and depression. 

**Methods:** The purpose of this systematic review and meta-analysis was to consolidate evidence on the effectiveness of in-person, co-designed mental health interventions for reducing anxiety and depression symptoms. An exhaustive search was conducted across six electronic databases (PubMed, PsycINFO, Embase, CINAHL, CENTRAL, and ProQuest) and grey literature. Criteria for inclusion comprised studies utilizing randomized or quasirandomized methods, implementing non-digital/in-person, co-designed interventions for mental health enhancement, and assessing anxiety and/or depression. Intervention impacts were evaluated using randomeffects meta-analyses. 

**Results:** The review identified 20 studies, with only three using the term &#039;co-design&#039;. Other terminologies included &#039;co-developed&#039; (n = 2), &#039;co-produced&#039; (n = 2), and &#039;CBPR&#039; (n = 11). Seventeen studies exhibited moderate risk of bias, while three demonstrated high risk. Meta-analyses demonstrated a moderate non-significant effect size of 0.5 (95 % CI: -0.8, 1.08; p = 0.08) on depression outcomes, and a small non-significant effect size of 0.12 (95 % CI: -0.1, 0.33; p = 0.23) on anxiety outcomes. 

**Limitations:** The majority of studies lacked sufficient statistical power to detect between-group differences. Following GRADE criteria, confidence in estimates was low. 

**Conclusions:** Notwithstanding widespread enthusiasm for co-design, the current evidence base is inadequate to confirm the impact of in-person, co-designed mental health interventions on anxiety and depression. More fullscale evaluation trials of higher quality are urgently needed, along with uniform terminology and measurement.
AN  - WOS:001176854900001
AU  - Barker,
AU  - T.
AU  - G.
AU  - O&#039;Higgins,
AU  - A.
AU  - Fonagy,
AU  - P.
AU  - Gardner,
AU  - F.
DB  - April 24.enl
DO  - 10.1016/j.jad.2023.12.080
L1  - internal-pdf://2381019430/1-s2.0-S0165032723015495-main.cleaned.pdf
PY  - 2024
SP  - 955-973
T2  - Journal of Affective Disorders
TI  - A systematic review and meta-analysis of the effectiveness of co-designed, in-person, mental health interventions for reducing anxiety and depression symptoms
UR  - &lt;Go to ISI&gt;://WOS:001176854900001
UR  - https://www.sciencedirect.com/science/article/pii/S0165032723015495?via%3Dihub
VL  - 350
ER  -
TY  - JOUR
AB  - QUESTION: Cognitive-behavioural therapy (CBT) is frequently implemented for individuals with attention-deficit hyperactivity disorder (ADHD). It is still unknown which specific components are effective, because CBT is a complex intervention with several components. The objective of this review was to assess the efficacy of CBT components for ADHD. 

STUDY SELECTION AND ANALYSIS: Building on definitions of the components used in CBT strategies, we conducted network meta-analyses to evaluate the efficacy at both the treatment level (ie, combinations of these components) and the component level (ie, individual component). Primary outcome was treatment response of ADHD core symptoms. Secondary outcomes were total ADHD symptoms, inattention symptoms, hyperactivity-impulsivity symptoms and dropout from the treatment. We searched MEDLINE (via PubMed), Embase, PsycINFO, ClinicalTrials.gov and Cochrane Library for literature published up to 31 March 2022. This review included only randomised controlled trials. 

FINDINGS: 43 trials with 3817 participants were included in the network meta-analyses. Third-wave therapy (OR=4.80, 95% credible interval (CrI) 2.50 to 9.10), behaviour therapy (OR=3.50, 95% CrI 1.70 to 7.30) and CBT (OR=3.10, 95% CrI 1.70 to 5.70) were treatments that demonstrated superior efficacy compared with placebo. The component-level analyses showed organisational strategies (incremental OR (iOR)=2.03, 95% CI 1.27 to 3.24) and third-wave components (iOR=1.95, 95% CI 1.30 to 2.93) were associated with increase in treatment response. Problem-solving techniques (incremental standardised mean difference=0.42, 95% CI 0.01 to 0.83) were associated with a reduction in inattention symptoms. 

CONCLUSIONS: Our findings suggest that the optimal treatment package for ADHD may include organisational strategies, third-wave components and problem-solving techniques. 

PROSPERO REGISTRATION NUMBER: CRD42022323898.
AN  - 39732478
AU  - Matsumoto,
AU  - K.
AU  - Hamatani,
AU  - S.
AU  - Kunisato,
AU  - Y.
AU  - Mizuno,
AU  - Y.
DB  - Desember 2024.enl
DO  - /10.1136/bmjment-2024-301303
L1  - internal-pdf://3844407356/Matsumoto-2024-Components of cognitive-behavio.pdf
PY  - 2024
SP  - 27
T2  - BMJ Mental Health
TI  - Components of cognitive-behavioural therapy for mitigating core symptoms in attention-deficit hyperactivity disorder: a systematic review and network meta-analys
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.1136%2fbmjment-2024-301303
UR  - https://mentalhealth.bmj.com/content/ebmental/27/1/e301303.full.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - This study systematically reviewed research on the use of digital game approaches for the prevention, assessment, and treatment of substance use and positive development in adolescents. **Background/Objectives**: This study aimed to identify and summarize gaps in the published literature on game-based digital interventions for substance use and positive development for adolescents through a systematic review. **Methods**: Following PRISMA guidelines, 26 studies were selected for final analysis from an initial screening of 1601 references. Data were coded for multiple components, including study characteristics, intervention types, intervention contents, sample characteristics, substance use, positive development details, measurement tools, and main findings, particularly emphasizing the effectiveness of game-based digital interventions and the facilitators and barriers affecting program effectiveness. **Results**: Regarding substance use, 50% of studies reported game-based digital interventions as effective in reducing substance use, 16.7% as partially effective, and 33.3% as not effective. For attitudes toward substance use, 65.0% demonstrated statistical effectiveness, 25.0% indicated partial effectiveness, and 10% found no significance. Among studies that included a positive development component, 35.7% were effective, 50% were partially effective, and 14.3% were not effective. Very few studies have explored the facilitators and barriers to program effectiveness without statistical verification. **Conclusions**: This study offers valuable insights into the development and validation of game-based digital interventions, thereby establishing a robust foundation for their efficacy.
AN  - 39767983
AU  - Lee,
AU  - S.
AU  - Kim,
AU  - J.
AU  - Bockhold,
AU  - S.
AU  - Lee,
AU  - J.
AU  - Chun,
AU  - J.
AU  - Yu,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3390/children11121554
L1  - internal-pdf://1800932754/Lee-2024-Game-Based Digital Interventions for.pdf
PY  - 2024
SP  - 21
T2  - Children
TI  - Game-Based Digital Interventions for Enhancing Positive Development and Addressing Substance Use in Adolescents: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3390%2fchildren11121554
UR  - https://mdpi-res.com/d_attachment/children/children-11-01554/article_deploy/children-11-01554-v2.pdf?version=1735003955
VL  - 11
ER  -
TY  - JOUR
AB  - OBJECTIVES: To evaluate the effectiveness of integrated models of mental healthcare in enhancing clinical outcomes, quality of life, satisfaction with care and health service delivery outcomes in young people aged 12-25 years. A secondary objective was to identify common components of integrated mental health interventions. 

METHODS: A systematic review and meta-analysis of studies published 2001-2023 that assessed clinical or health service use outcomes of integrated care, relative to treatment as usual, for any mental health condition in 12-25 years old accessing community-based care.

RESULTS: Of 11,444 titles identified, 15 studies met inclusion criteria and 6 studies were entered in the meta-analysis. Pooled effect size found integrated care was associated with a greater reduction in depressive symptoms relative to treatment as usual at 4-6 months (standardised mean difference = -0.260, 95% confidence interval = [-0.39, -0.13], p = 0.001). Of the seven studies reporting access or engagement, all reported higher rates of both in the intervention arm. The most frequent components of integration were use of a multidisciplinary team (13/15 studies), shared treatment planning (11/15) and workforce training in the model (14/15). 

CONCLUSIONS: Integrated models of mental healthcare are associated with a small, but significant, increase in effectiveness for depressive symptoms relative to treatment as usual. Given integrated care may increase access and engagement, future research should focus on assessing the impact of integrated care in a wider range of settings and outcomes, including clinical and functional recovery, satisfaction with care and system-level outcomes such as cost-effectiveness.
AN  - 38847297
AU  - McHugh,
AU  - C.
AU  - Hu,
AU  - N.
AU  - Georgiou,
AU  - G.
AU  - Hodgins,
AU  - M.
AU  - Leung,
AU  - S.
AU  - Cadiri,
AU  - M.
AU  - Paul,
AU  - N.
AU  - Ryall,
AU  - V.
AU  - Rickwood,
AU  - D.
AU  - Eapen,
AU  - V.
AU  - Curtis,
AU  - J.
AU  - Lingam,
AU  - R.
DB  - Juni 24.enl
DO  - /10.1177/00048674241256759
L1  - internal-pdf://3497881279/mchugh-et-al-2024-integrated-care-models-for-y.pdf
PY  - 2024
SP  - 48674241256759
T2  - Australian and New Zealand Journal of Psychiatry
TI  - Integrated care models for youth mental health: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1177%2f00048674241256759
UR  - https://journals.sagepub.com/doi/10.1177/00048674241256759
ER  -
TY  - JOUR
AB  - Background and Objective: Depression is a long-term mood condition that produces sorrow, loss of pleasure and interest, frequently with cognitive impairment. The incidence and lifetime prevalence of depression in children and adolescents are rising across all patient categories. According to statistics, 20% of teens experience significant depression. This study conducted a comprehensive review to analyse the impact of combining fluoxetine with cognitive behaviour therapy in the treatment of non-suicidal self-injury in adolescents. 

Materials and Methods: The Cochrane Library, PubMed, Embase and Web of Science were searched for controlled trials of fluoxetine and cognitive behaviour therapy for depressed adolescents. Screening and extracting material for systematic review occurred between database inception and May, 2023. 

Results: Seven trials included 893 participants. The systematic review found that the intervention group had a significantly higher rate of remission (OR: 1.11; 95% Cl: 1.03, 1.20; p&lt;0.01) than the untreated group. The two groups of patients had similar rates of recurrence, self-injury adverse events and overall adverse events (OR: 0.96; 95% CI: 0.57, 1.61; p = 0.868). 

Conclusion: This study demonstrated the stability and reliability of fluoxetine and cognitive behaviour therapy for depressed teenagers. The findings showed that fluoxetine and cognitive behaviour therapy may help depressed teenagers remit.
AN  - WOS:001337978400001
AU  - Zhao,
AU  - S.
AU  - J.
AU  - Zhang,
AU  - D.
AU  - X.
AU  - Lu,
AU  - Y.
AU  - R.
DB  - November 2024.enl
DO  - 10.3923/ijp.2024.916.925
L1  - internal-pdf://3597433489/916-925.cleaned.pdf
PY  - 2024
SP  - 916-925
T2  - International Journal of Pharmacology
TI  - Efficacy of Fluoxetine Combined with Cognitive Behavior Therapy in Treating Non-Suicidal Self-Injury in Adolescents: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001337978400001
VL  - 20
ER  -
TY  - JOUR
AB  - BACKGROUND: The prevalence of mental illness increased in children, adolescents, and young adults during the COVID-19 pandemic, while at the same time, access to treatment facilities has been restricted, resulting in a need for the quick implementation of remote or online interventions. 

OBJECTIVE: This study aimed to give an overview of randomized controlled studies examining remote or online interventions for mental health in children, adolescents, and young adults and to explore the overall effectiveness of these interventions regarding different symptoms. 

METHODS: A systematic literature search was conducted according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines using PubMed, PsycInfo, Psyndex, Embase, and Google Scholar. A meta-analysis was conducted using a random effects model to calculate overall effect sizes for interventions using standardized mean differences (SMDs) for postintervention scores. 

RESULTS: We identified 17 articles with 8732 participants in the final sample, and 13 were included in the quantitative analysis. The studies examined different digital interventions for several outcomes, showing better outcomes than the control in some studies. Meta-analyses revealed significant medium overall effects for anxiety (SMD=0.44, 95% CI 0.20 to 0.67) and social functioning (SMD=0.42, 95% CI -0.68 to -0.17) and a large significant effect for depression (SMD=1.31, 95% CI 0.34 to 2.95). In contrast, no significant overall treatment effects for well-being, psychological distress, disordered eating, and COVID-19-related symptoms were found. 

CONCLUSIONS: The qualitative and quantitative analyses of the included studies show promising results regarding the effectiveness of online interventions, especially for symptoms of anxiety and depression and for training of social functioning. However, the effectiveness needs to be further investigated for other groups of symptoms in the future. All in all, more research with high-quality studies is required.
AN  - 38315524
AU  - Fischer-Grote,
AU  - L.
AU  - Fossing,
AU  - V.
AU  - Aigner,
AU  - M.
AU  - Fehrmann,
AU  - E.
AU  - Boeckle,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.2196/46637
L1  - internal-pdf://4292225035/pdf.cleaned (9).pdf
PY  - 2024
SP  - e46637
T2  - JMIR Mental Health
TI  - Effectiveness of Online and Remote Interventions for Mental Health in Children, Adolescents, and Young Adults After the Onset of the COVID-19 Pandemic: Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38315524
VL  - 11
ER  -
TY  - JOUR
AB  - Purpose: Out-of-school adolescent girls (OoSGs) can lack education on menstrual, sexual, reproductive, and mental health (SRMH) and be more vulnerable to SRMH harms. Targeted interventions could reduce these risks. We assessed interventions and their effectiveness among OoSGs globally. 

Methods: Six online databases were searched for interventional studies targeting SRMH problems in OoSGs. Two coders independently abstracted data from each eligible study, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We summarized results using forest plots. 

Results: A total of 1,244 studies were screened; eight studies with sufficient information on SRMH outcomes were included (9,084 OoSGs, range 100-3,026 per study, overall study quality low-to-moderate). Six were educational programmes, and two were cash interventions; no study was directed at mental health. Participants were recruited through village census, outreach workers, and work locations. Some improvements were seen in indicators of SRMH knowledge (four studies), attitudes (one study), and risky sexual behaviors (four studies); however, no reduction was seen in human immunodeficiency virus or herpes simplex virus-2 incidence (two studies). 

Discussion: This review suggests that programmes can improve OosG&#039;s SRMH knowledge, attitudes, and practices and can be delivered in low resource contexts. Effective interventions are needed to support OoSGs, including interventions focusing on SRMH support incorporating elements of cash-transfer, and comprehensive sexual education, and to aid local policy and programming.
AN  - 39703482
AU  - Farquharson,
AU  - K.
AU  - Quinn-Savory,
AU  - A.
AU  - Zulaika,
AU  - G.
AU  - Mason,
AU  - L.
AU  - Nungo,
AU  - S.
AU  - Nyothach,
AU  - E.
AU  - Unger,
AU  - H.
AU  - Sivakami,
AU  - M.
AU  - Spinhoven,
AU  - P.
AU  - Phillips-Howard,
AU  - P.
AU  - A.
AU  - van
AU  - Eijk,
AU  - A.
AU  - M.
DB  - Desember 2024.enl
DO  - /10.3389/fpubh.2024.1440930
L1  - internal-pdf://2903177855/Farquharson-2024-Interventions aiming to impro.pdf
PY  - 2024
SP  - 1440930
T2  - Frontiers in Public Health
TI  - Interventions aiming to improve menstrual, sexual, reproductive, and mental health among out-of-school girls: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.3389%2ffpubh.2024.1440930
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11656019/pdf/fpubh-12-1440930.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - INTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) is a complex neurodevelopmental disorder. It is one of the most common mental disorders in youth worldwide characterized by persistent overactivity and impulsivity/inattention symptoms associated with social and academic impairment. dasotraline has been suggested to play a pivotal role as a serotonin, norepinephrine, and dopamine reuptake inhibitor. This study aimed to create evidence from published randomized clinical trials (RCTs) about the benefits of dasotraline for ADHD patients. 

METHODS: A computer literature search (PubMed, Scopus, Web of Science, and Cochrane CENTRAL) was conducted. We included RCTs comparing dasotraline versus placebo. The primary outcome measure was the ADHD Rating Scale-IV score, pooled as the mean difference between the two groups from baseline to the endpoint. The secondary outcome measures were the ADHD Rating Scale-IV Inattention score, ADHD Rating Scale-IV Hyperactivity score. 

RESULTS: Five RCTs with a total of 1594 patients were included in this study. dasotraline showed a significant improvement in the primary outcome (MD -2.65, 95% CI [-4.14 to -1.17], P= 0.0004 

CONCLUSION: The results showed that dasotraline demonstrated a significant improvement in both primary and secondary outcomes, establishing its efficacy as a novel treatment for ADHD symptoms. However, mild to moderate side effects were observed.
AN  - 39702840
AU  - Mansour,
AU  - M.
AU  - E.
AU  - M.
AU  - Alsaadany,
AU  - K.
AU  - R.
AU  - Ahmed,
AU  - M.
AU  - A.
AU  - E.
AU  - Elmetwalli,
AU  - A.
AU  - E.
DB  - Desember 2024.enl
DO  - /10.1007/s00213-024-06723-5
L1  - internal-pdf://4204133507/ea7b62ba-c39a-4892-a920-a853c167e9ff.pdf
PY  - 2024
SP  - 19
T2  - Psychopharmacology
TI  - Safety and efficacy of dasotraline for patients with attention deficit/hyperactivity disorder: a systematic review and meta-analysis of 1594 patients including GRADE qualifications
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs00213-024-06723-5
UR  - https://link.springer.com/article/10.1007/s00213-024-06723-5
VL  - 19
ER  -
TY  - JOUR
AB  - Aim: Type 1 diabetes (T1D) is one of the most common chronic conditions in children and adolescents. Approximately 1.5 million young people are currently living with T1D throughout the world. Despite recent improvement in overall indices of metabolic control in children and adolescents with T1D, control remains suboptimal and additional approaches are needed. The aim of the study was to conduct a systematic review and meta-analysis of educational and psychoeducational self-management interventions, to help optimize future interventions including physical activity support.

Methods: A systematic review and meta-analysis were conducted according to our registered protocol (PROSPERO CRD42022295932) and are reported in line with the PRISMA 2020 guidance. We searched five databases (MEDLINE, EMBASE, PsycINFO [via Ovid], CINAHL [via EBSCO], Cochrane Library) from 1994 up to May 2024. We included randomized controlled trials assessing the effectiveness of self-management interventions. Outcomes of interest included HbA1c and quality of life (QoL) as well as self-care behaviors, diabetes knowledge, and self-efficacy. Meta-analyses were conducted using a random effects model.

Results: In total, 46 papers were included, reporting on 30 interventions. Meta-analyses showed small short-term improvements in HbA1c (MD = -2.58 mmol/L, 95% CI -4.44 to -0.71, p=0.007) and QoL (mean difference [MD] = 1.37, 95% CI 0.19-2.54, p=0.02). Prespecified subgroup analyses suggested no significant difference in effectiveness of psychoeducational and education-only interventions. Quality of included studies was low with 27 having a high risk of bias.

Conclusion: There is a lack of robust evidence that current self-management interventions result in clinically meaningful improvements in HbA1c and QoL. Future research should focus on redefining approaches to supporting and encouraging self-management.
AN  - WOS:001336271100001
AU  - Cockcroft,
AU  - E.
AU  - J.
AU  - Clarke,
AU  - R.
AU  - Dias,
AU  - R.
AU  - P.
AU  - Lloyd,
AU  - J.
AU  - Mann,
AU  - R.
AU  - H.
AU  - Narendran,
AU  - P.
AU  - Reburn,
AU  - C.
AU  - Smith,
AU  - B.
AU  - Smith,
AU  - J.
AU  - R.
AU  - Andrews,
AU  - R.
AU  - C.
DB  - November 2024.enl
DO  - 10.1155/2024/2921845
L1  - internal-pdf://3472591003/Pediatric Diabetes - 2024 - Cockcroft - Effect.pdf
PY  - 2024
SP  - 19
T2  - Pediatric Diabetes
TI  - Effectiveness of Educational and Psychoeducational Self-Management Interventions in Children and Adolescents With Type 1 Diabetes: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001336271100001
VL  - 2024
ER  -
TY  - JOUR
AB  - OBJECTIVE: We conducted an umbrella review of systematic reviews (SRs), with or without meta-analysis (MA), of randomized controlled trials (RCTs) assessing nonpharmacological sleep interventions for children and adolescents across various clinical populations. 

METHOD: We searched multiple electronic databases up to January 24, 2024. Meta-analyzable data from RCTs in the retrieved SRs/MAs were pooled using Metaumbrella. Primary outcomes were subjective/objective child sleep parameters. Additional outcomes included child health/functioning and parental sleep/health. The quality of the MAs/SRs was assessed with Assessment of Multiple Systematic Reviews (AMSTAR-2), and the certainty of evidence using Grading of Recommendations, Assessment, Development and Evaluations (GRADE). 

RESULTS: We included 93 SRs/MAs covering 393 RCTs, with 25 (17%, 39%, and 30%: high, moderate, and low quality) providing data for quantitative synthesis. Behavioral interventions, usually multicomponent including parent training, psychoeducation, and/or specific sleep therapy/strategies, showed beneficial effects on night waking, sleep duration, overall sleep disturbance, mood/depression, and maternal sleep quality (standardized mean difference [SMD] = 0.10-0.80) in participants with sleep problems without a formal sleep disorder diagnosis. For those with a formal diagnosis (mainly insomnia), benefits were found for night waking, sleep efficiency (subjective/actigraphically measured), and sleep onset latency (mean SMD = 0.49-0.97). Those with attention-deficit/hyperactivity disorder (ADHD) improved in bedtime resistance, night waking, parasomnias, sleep anxiety, ADHD symptoms, sleep disturbance, and quality of life (mean SMD = 0.18-0.49). For those with autism, sleep disturbance improved (mean SMD = 0.70). However, all findings were of low to very low certainty of evidence.

CONCLUSION: Among nonpharmacological interventions for sleep difficulties in youth, only behavioral interventions are supported by meta-analytic evidence, yet with small-to-moderate effect sizes and limited certainty of evidence. 

STUDY PREREGISTRATION INFORMATION: The efficacy and tolerability of nonpharmacological interventions for sleep problems in children and adolescents: protocol for an umbrella review of systematic reviews and meta-analyses of randomised controlled trials. https://osf.io; j9qna/.
AN  - 39608635
AU  - Hornsey,
AU  - S.
AU  - J.
AU  - Gosling,
AU  - C.
AU  - J.
AU  - Jurek,
AU  - L.
AU  - Nourredine,
AU  - M.
AU  - Telesia,
AU  - L.
AU  - Solmi,
AU  - M.
AU  - Butt,
AU  - I.
AU  - Greenwell,
AU  - K.
AU  - Muller,
AU  - I.
AU  - Hill,
AU  - C.
AU  - M.
AU  - Cortese,
AU  - S.
DB  - Desember 2024.enl
DO  - /10.1016/j.jaac.2024.10.015
L1  - internal-pdf://2678520385/0ab815b7-b03f-4777-973c-e4f53b9f441e.pdf
PY  - 2024
SP  - 26
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Umbrella Review and Meta-Analysis: The Efficacy of Nonpharmacological Interventions for Sleep Disturbances in Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jaac.2024.10.015
UR  - https://www.sciencedirect.com/science/article/pii/S0890856724020215?via%3Dihub
VL  - 26
ER  -
TY  - JOUR
AB  - Autism spectrum disorder (ASD) represents a multifaceted neurodevelopmental condition characterized by challenges in communication, social interaction, and the presence of repetitive behavioral patterns. The emergence of the COVID-19 pandemic has spurred a growing interest among researchers to utilize remote physical activity as a means of intervention for individuals with ASD. To our knowledge, there have been a limited number of comprehensive meta-analyses conducted to assess the impact of web-based physical activity (WBPA) interventions. This study aims to consolidate existing evidence from previous research exploring the effects of WBPA on physical activity levels in individuals with ASD, as well as its impact on caregivers&#039; mental well-being and satisfaction with WBPA programs. We reviewed a total of 10 research studies focused on WBPA programs for individuals with ASD and their caregivers, involving 358 participants, with 158 being individuals with ASD and 200 being caregivers. Among these, one study was qualitative, five were quantitative, and four were mixed-method studies. The findings reveal that WBPA has the potential to enhance the physical activity levels of ASD individuals and positively affect the mental health of caregivers. Furthermore, it is noteworthy that the majority of caregivers expressed high levels of satisfaction with this particular form of intervention.
AN  - WOS:001307239500001
AU  - Liu,
AU  - J.
AU  - Shen,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1080/20473869.2024.2394737
L1  - internal-pdf://0210828088/Web-based physical activity programs for indiv.pdf
PY  - 2024
SP  - 14
T2  - International Journal of Developmental Disabilities
TI  - Web-based physical activity programs for individuals with autism spectrum disorder and their parents: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001307239500001
ER  -
TY  - JOUR
AB  - Background: The Centers for Disease Control and Prevention stated that about 1 in every 44 children between the ages of 4 and 8 years old had been identified with autism spectrum disorder (ASD). Complementary interventions such as massage are crucial for the improvement of the health outcomes of ASD patients, such as abnormal sensory response; Autism Behavior Checklist; parenting stress, self-regulatory difficulties, social, language, and communication abilities; tactile or oral abnormalities; Vineland daily living skills; Vineland socialization; Childhood Autism Rating Scale; Preschool Language Scale 5th Edition (PLS-5) auditory communication; and PLS-5 expressive communication. 

Purpose: We aim to systematically investigate the effects of different types of massage on self-regulatory difficulties, tactile and oral abnormalities, and parenting stress in children with ASD. 

Methods: PubMed, Cochrane Library, Scopus, and Web of Science were scoured from their inception through November 15, 2022. Research comparing massage efficacy in children with ASD to other methods or a control group was included. For randomized controlled trials (RCTs), we utilized the Cochrane risk of bias tool; and for cohort studies, we used the tool developed by the National Institutes of Health. Meta-analysis was carried out with Review Manager 5.4. For our continuous data, we calculated the mean difference (MD) and 95% confidence interval (95% CI). 

Results: We included 10 studies with a total number of 485 children with autism. Our analysis showed a significant decrease in the massage group regarding self-regulatory difficulties (MD = -9.15; 95% CI (-13.69 to -4.60), p &lt; 0.0001). Also, the massage group showed a significant decrease in tactile or oral abnormalities compared with the control group (MD = -4.83; 95% CI (-7.86 to -1.80), p = 0.002). Moreover, parenting stress significantly decreased in the massage group compared to the control group (MD = -4.31; 95% CI (-7.02 to -1.61), p = 0.002).

Conclusion: Qigong and traditional Thai massage improved self-regulatory difficulties and decreased tactile or oral abnormalities in children with autism. Moreover, they decreased parenting stress. However, we need more RCTs with larger sample sizes with high quality to assess the different types of massage effects on autistic children and produce more valid results. So, Qigong and traditional Thai massage could be used as a complement to educational and training interventions in children with autism.
AN  - 39669546
AU  - Fadlalmola,
AU  - H.
AU  - A.
AU  - Abedelwahed,
AU  - H.
AU  - H.
AU  - Hamid,
AU  - H.
AU  - I.
AU  - Ali,
AU  - A.
AU  - B.
AU  - Algadi,
AU  - H.
AU  - A.
AU  - A.
AU  - Farg,
AU  - S.
AU  - J.
AU  - Ali,
AU  - N.
AU  - M.
AU  - A.
AU  - Elbashir,
AU  - A.
AU  - A.
AU  - Mohammed,
AU  - M.
AU  - H.
AU  - Mohmmed,
AU  - S.
AU  - S.
AU  - Mousa,
AU  - S.
AU  - A.
AU  - Gaafar,
AU  - D.
AU  - A.
AU  - Eltyeb,
AU  - A.
AU  - A.
DB  - Desember 2024.enl
DO  - /10.3822/ijtmb.v17i4.1079
L1  - internal-pdf://1246951095/Fadlalmola-2024-Effects of Massage on Self-reg.pdf
PY  - 2024
SP  - 4-19
T2  - International Journal of Therapeutic Massage &amp; Bodywork
TI  - Effects of Massage on Self-regulatory Difficulties, Tactile and Oral Abnormalities, and Parenting Stress in Children with Autism Spectrum Disorder (ASD): A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3822%2fijtmb.v17i4.1079
UR  - https://ijtmb.org/index.php/ijtmb/article/download/1079/1157
VL  - 17
ER  -
TY  - JOUR
AB  - This study aimed to examine the effectiveness of dropout intervention programs among K-12 students. A total of 26 empirical studies published between 2010 and 2022 were included, from which 31 effect sizes were extracted. The average effect size for the dropout intervention programs on increasing high school completion was estimated as 0.19 (95% CI: 0.10, 0.28). We found that both nonrandomly assigned but matched designs and randomly assigned designs tended to have larger effect sizes compared to nonrandom designs. Behavioral interventions (ES = 0.33) and combined interventions that implemented at least two kinds of intervention strategies (ES = 0.31) performed better than programs focused on academics alone (ES = 0.12) in terms of preventing dropout and promoting graduation rate. We suggest educators and policymakers include behavioral components when developing intervention programs. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2024-81833-001
AU  - Wang,
AU  - Q.
AU  - Hsiao,
AU  - Y.-Y.
AU  - Hushman,
AU  - C.
AU  - Armstrong,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1080/10824669.2024.2342779
L1  - internal-pdf://4022299279/The Effectiveness of Dropout Intervention Prog.pdf
PY  - 2024
SP  - No Pagination Specified
T2  - Journal of Education for Students Placed at Risk
TI  - The effectiveness of dropout intervention programs among k-12 students: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.1080%2f10824669.2024.2342779
ER  -
TY  - JOUR
AB  - BACKGROUND: Invasive procedures are commonly used in pediatric healthcare, and storybooks can be used as an adjunct analgesic method. 

OBJECTIVES: This study was conducted to evaluate the effectiveness of using storybooks as a distraction technique to reduce fear and anxiety in pediatric healthcare. This study was conducted with the aim of revealing the level of effect of storybook use on children&#039;s fear and anxiety level in pediatric health services. 

METHODS: For this meta-analysis study, the studies were obtained by searching PubMed, Web of Science, Scopus, EBSCOhost, Google Scholar and YOK Thesis Center databases in April-June 2024 without any year limitation. After the reviews, 15 studies were included in the study. The data were synthesized by meta-analysis and narrative methods. 

FINDINGS: In this meta-analysis, it was found that storybook use in pediatric health services was effective on children&#039;s anxiety (SMD: -4.412, 95 % CI: -7.727 to -1.097; Z = -2.608, p = 0.009; I&lt;sup&gt;2&lt;/sup&gt; = 99.890 %) and fear (SMD: -1.13, 95 % CI: -1.71 to -0.54; Z = -3.78, p = 0.000; I&lt;sup&gt;2&lt;/sup&gt; = 83.065 %) levels. In addition, it was determined that the characteristics of the intervention group, age group, the characteristics and content of the storybook, the duration of the intervention and the time of the intervention played a role in the effectiveness of the storybook use intervention in pediatric health services on children&#039;s anxiety and fear levels. 

CONCLUSION: The use of story books in children&#039;s health services reduces the level of fear and anxiety in children.
AN  - 39730287
AU  - Akay,
AU  - G.
AU  - Uzun,
AU  - S.
AU  - Oguzhan,
AU  - H.
AU  - Guducu
AU  - Tufekci,
AU  - F.
DB  - Desember 2024.enl
DO  - /10.1016/j.pedn.2024.12.006
L1  - internal-pdf://4024235843/a939a376-ba67-4a9e-bafb-339be2932c56.pdf
PY  - 2024
SP  - 26
T2  - Journal of Pediatric Nursing
TI  - The Effect of storybook use in pediatric health services on children&#039;s fear and anxiety levels: A meta-analysis study
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.pedn.2024.12.006
UR  - https://www.sciencedirect.com/science/article/pii/S0882596324004512?via%3Dihub
VL  - 26
ER  -
TY  - JOUR
AB  - BACKGROUND: Growing evidence suggests that physical activity (PA) could improve cognitive performance in youths, but whether these effects occur from early childhood remains unclear. 

OBJECTIVE: To summarize evidence on the effects of PA interventions on cognitive performance in early childhood. 

METHODS: We performed a systematic search in PubMed, Scopus, Web of Science and PsycINFO (from inception to 6 september 2023) for randomized controlled trials assessing the effects of PA interventions (&gt;= 3 weeks) on cognitive-related outcomes in early childhood (3-6 years). We conducted a random-effects meta-analysis when five or more studies assessed a given outcome. The potential moderating role of participant (e.g., age) and intervention characteristics (e.g., duration, volume, intensity, cognitive engagement) was also assessed. 

RESULTS: We found a total of 24 studies (N = 3483 children) that were deemed to be of overall fair methodological quality. PA interventions were supervised and lasted between 3 and 24 weeks. The most common session duration was 30 min, with a frequency of two sessions per week. Pooled analyses revealed that PA interventions have positive effects on all analysed outcomes, including attention (standardized mean difference (SMD) = 0.49, 95% confidence interval (CI) 0.18-0.79, p = 0.002), inhibition (SMD = 0.45, 95% CI 0.06-0.84, p = 0.022), working memory (SMD = 0.50, 95% CI 0.18-0.82, p = 0.002), cognitive flexibility (SMD = 0.39, 0.15-0.62, p = 0.002) and vocabulary (SMD = 1.18, 0.19-2.16, p = 0.019). Sensitivity analyses confirmed the benefits in all cases except for inhibition (p = 0.062). No consistent differences were found relating to any moderator variable. 

CONCLUSIONS: Although further research is warranted, our findings suggest that PA interventions may improve cognitive performance in early childhood, particularly in the domains of attention, inhibition, working memory, cognitive flexibility and vocabulary. These findings might support the implementation of PA interventions from early childhood. <b>PROSPERO REGISTRATION</b>: CRD42021249319.
AN  - 38598150
AU  - Morales,
AU  - J.
AU  - S.
AU  - Alberquilla
AU  - Del
AU  - Rio,
AU  - E.
AU  - Valenzuela,
AU  - P.
AU  - L.
AU  - Martinez-de-Quel,
AU  - O.
DB  - Juli 2024.enl
DO  - /10.1007/s40279-024-02020-5
L1  - internal-pdf://0296172158/Morales-2024-Physical Activity and Cognitive P.pdf
PY  - 2024
SP  - 1835-1850
T2  - Sports Medicine
TI  - Physical Activity and Cognitive Performance in Early Childhood: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1007%2fs40279-024-02020-5
UR  - https://link.springer.com/article/10.1007/s40279-024-02020-5
UR  - https://link.springer.com/content/pdf/10.1007/s40279-024-02020-5.pdf
VL  - 54
ER  -
TY  - JOUR
AB  - Objective: To evaluate the comparative efficacy of pharmacological interventions for children and adolescents with a dual diagnosis of persistent tic disorders or Tourette disorder and attention-deficit/hyperactivity disorder (TD + ADHD). 

Methods: We searched CENTRAL, Embase, PubMed, PsycInfo, Web of Sciences, ClinicalTrials.gov, and WHO ICTRP up to September 2023 to identify double-blinded randomized controlled trials (RCTs) assessing pharmacological interventions for children and adolescents with TD + ADHD. Outcomes were change in ADHD symptoms (primary) and tics (secondary) severity. Standardized mean difference (SMD) was calculated and pooled in random-effects network meta-analysis. The Confidence in Network Meta-Analysis framework was adopted to determine certainty of evidence. 

Results: We included 8 RCTs involving 575 participants. Network meta-analyses demonstrated that alpha2 agonists (SMD, 95% confidence interval [CI] ADHD: -0.72 [-1.13 to -0.31]; TD: -0.70 [-0.96 to -0.45]) and stimulants + alpha2 agonists (ADHD: -0.84 [-1.54 to -0.13]; TD: -0.60 [-1.04 to -0.17]) were more efficacious than placebo for ADHD symptoms and tics severity. Stimulants alone were more efficacious than placebo for ADHD symptoms severity only, but they did not worsen tics (ADHD: -0.54 [-1.05 to -0.03]; TD: -0.22 [-0.49 to 0.05]). There were no significant differences between any pairs of medications that were found efficacious against placebo for ADHD symptoms or tics severity. Certainty in the evidence varied from low to very low. 

Conclusions: Stimulants are efficacious for ADHD symptoms severity and do not increase tics severity in TD + ADHD. alpha2 agonists are efficacious for both ADHD symptoms and tics severity in TD + ADHD. These findings should inform guidelines and help guide shared decision-making to choose a medication for children with TD + ADHD.
AN  - 39320340
AU  - Farhat,
AU  - L.
AU  - C.
AU  - Behling,
AU  - E.
AU  - Landeros-Weisenberger,
AU  - A.
AU  - Macul
AU  - Ferreira
AU  - de
AU  - Barros,
AU  - P.
AU  - Polanczyk,
AU  - G.
AU  - V.
AU  - Cortese,
AU  - S.
AU  - Bloch,
AU  - M.
AU  - H.
DB  - September 2024.enl
DO  - /10.1089/cap.2024.0049
L1  - internal-pdf://1855151522/farhat-et-al-2024-pharmacological-intervention.pdf
PY  - 2024
SP  - 24
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Pharmacological Interventions for Attention-Deficit/Hyperactivity Disorder in Children and Adolescents with Tourette Disorder: A Systematic Review and Network Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1089%2fcap.2024.0049
VL  - 24
ER  -
TY  - JOUR
AB  - BACKGROUND: Hospitalization often induces anxiety and fear in children, which may lead to maladaptive behaviours. Prior research has found that storytelling can help improve children&#039;s communication and reduce their stress. Not only does it enhance children&#039;s ability to express their emotions more effectively and comfortably, it also assists them in releasing negative emotions like anxiousness and fear. 

OBJECTIVES: To evaluate the effectiveness of storytelling in reducing children&#039;s anxiety and/or fear during hospitalization. 

METHODS: A systematic review and meta-analysis were conducted. The search spanned across eight online databases from their inception dates to January 2024. The Cochrane Risk of Bias Tool was utilized to perform quality appraisals. Effects model was utilized to conduct the meta-analysis. Subgroup analyses were conducted for age of participants, geographical location and measurement used. 

FINDINGS: A total of eight studies were included in this review. Compared to standard care, storytelling was found to be effective in reducing anxiety and/or fear in children during hospitalization. Anxiety scores were not affected by the participants&#039; age, but the geographical location and type of measurement scales used showed significant subgroup differences. 

CONCLUSION&gt;: Storytelling interventions help to reduce anxiety and fear levels in hospitalized children. It was suggested that hospitals could provide the necessary training to healthcare workers to perform storytelling more effectively. Additionally, involvement of parents in storytelling could be encouraged, ensuring continuity even after discharge. Further research can be conducted in more diverse geographical regions and explore how storytelling content can vary across different ages.
AN  - 39547077
AU  - Ku,
AU  - S.
AU  - H.
AU  - Chua,
AU  - J.
AU  - S.
AU  - Shorey,
AU  - S.
DB  - November 2024.enl
DO  - /10.1016/j.pedn.2024.11.006
L1  - internal-pdf://1042908464/1-s2.0-S0882596324004214-main.cleaned.pdf
PY  - 2024
SP  - 41-48
T2  - Journal of Pediatric Nursing
TI  - Effect of storytelling on anxiety and fear in children during hospitalization: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.pedn.2024.11.006
UR  - https://www.sciencedirect.com/science/article/pii/S0882596324004214?via%3Dihub
VL  - 80
ER  -
TY  - JOUR
AB  - Background
Early executive functioning (EF) skills are foundational capabilities that predict school readiness, academic development and psychiatric risk. Early interventions enhancing these capabilities could have critical import in improving outcomes. However, to develop interventions, it is necessary to identify specific EF skills that will vary with child age. Thus, we aimed to examine the characteristics and efficacy of interventions targeting EF in infancy and early childhood up to age 3.

Methods
A comprehensive search of PubMed, Embase, CINAHL and APA PsycINFO databases was performed for studies published before December 2022. Randomized and non-randomized studies of interventions designed to improve at least one EF skill in children &le;3 years were included. EF skills included attentional control, inhibition/self-regulation, activity initiation, working memory, cognitive flexibility, planning ability, problem-solving and performance monitoring. We independently extracted data, used the revised Cochrane Risk-of-Bias tool to assess the quality of the evidence and conducted Synthesis Without Meta-analysis (SWiM). The overall quality of the evidence and the strength of recommendations was determined using elements of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.

Results
Thirty-five studies met inclusion criteria (original n =&thinsp;7467). Studies were highly variable in the EF skill targeted, target subject (i.e., child, parent and teacher), nature and dosage of the intervention, and timing of outcome assessment. Most interventions focused on improving impulse control and self-regulation. The overall quality of evidence was low to moderate with a high risk of bias, though six studies had low risk of bias but yielded mixed findings of efficacy.

Conclusions
The relatively small number of early EF intervention studies uses such variable methods that there is currently no converging evidence of efficacy to recommend a specific intervention. Thus, findings support the need for a more systematic, targeted approach to the design and implementation of early EF interventions for target populations.
AN  - WOS:001260786300001
AU  - Duncan,
AU  - A.
AU  - F.
AU  - Gerner,
AU  - G.
AU  - J.
AU  - Neel,
AU  - M.
AU  - L.
AU  - Burton,
AU  - V.
AU  - J.
AU  - Byrne,
AU  - R.
AU  - Warschausky,
AU  - S.
DB  - Juli 2024.enl
DO  - 10.1111/cch.13298
L1  - internal-pdf://3893181210/Duncan-2024-Interventions to improve executive.pdf
PY  - 2024
SP  - 23
T2  - Child Care Health and Development
TI  - Interventions to improve executive functions in children aged 3 years and under: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:001260786300001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cch.13298?download=true
VL  - 50
ER  -
TY  - JOUR
AB  - Objective: Evidence on the efficacy of social skills training for adolescents with Level 1 Autism Spectrum Disorder (ASD) is unclear. 

Method: We searched Pubmed, Scopus, and Web of Science until July 27th, 2023, for randomized controlled trials (RCTs) of social skills training for pre-adolescents and adolescents (aged 9-18) with Level 1 ASD. We then pooled data on efficacy from individual RCTs by conducting multivariate mixed-effects meta-analyses in R. We estimated possible bias in the retained RCTs using the RoB2 tool. 

Results: We retained 36 RCTs (encompassing 2796 participants), including 18 RCTs comparing an experimental treatment to a waiting list, and 18 RCTs comparing it to standard care/control treatment. Meta-analyses showed that experimental treatments were significantly more efficacious than waiting list or standard care/ control treatments in improving social skills (SMD = 0.3745; 95%CI = [0.2396; 0.5093]), as well as reducing behavioral symptoms (0.3154;0.1783, 0.4525) and anxious/depressive symptoms (0.2780; 0.0432, 0.5128). However, for some outcomes there was significant heterogeneity across studies and evidence of publication bias. Subgroup analyses and meta-regressions did not identify any specific clinical or demographic factors as significant predictors of outcome. The most common risk of bias across studies was related to deviations from intended interventions and measurement of the outcomes. 

Conclusions: At the group level, social skills training for adolescents with Level 1 ASD is efficacious, with small-to-moderate effect size. Future research should focus on personalized medicine approaches, aimed at tailoring interventions to specific characteristics of adolescents with Level 1 ASD.
AN  - 38988677
AU  - Narzisi,
AU  - A.
AU  - Sesso,
AU  - G.
AU  - Fabbri-Destro,
AU  - M.
AU  - Berloffa,
AU  - S.
AU  - Fantozzi,
AU  - P.
AU  - Muccio,
AU  - R.
AU  - Bruzzi,
AU  - G.
AU  - Scatigna,
AU  - S.
AU  - Valente,
AU  - E.
AU  - Viglione,
AU  - V.
AU  - Milone,
AU  - A.
AU  - Cortese,
AU  - S.
AU  - Masi,
AU  - G.
DB  - Juli 2024.enl
DO  - /10.36131/cnfioritieditore20240302
L1  - internal-pdf://2496675071/Narzisi-2024-Social Skills Interventions for A.pdf
PY  - 2024
SP  - 169-181
T2  - Clinical Neuropsychiatry
TI  - Social Skills Interventions for Adolescents with Level 1 Autism Spectrum Disorder: A Systematic Review with Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.36131%2fcnfioritieditore20240302
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11231730/pdf/cn-21-169.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - PURPOSE: To review studies that have intervention in reading with impacts on phonological awareness in children with autism spectrum disorder. 

RESEARCH STRATEGIES: Searches took place until February 2021 in Cochrane, Embase, ERIC (Education Resources Information Center), LILACS (Latin American and Caribbean Health Sciences Literature), PubMed/Medline, Scopus, Web of Science and gray literature databases. 

SELECTION CRITERIA: The review included experimental studies with preschoolers and schoolchildren with ASD. Two independent reviewers selected the studies and, in case of disagreement, a third reviewer was consulted. &uml;

DATA ANALYSIS Joanna Briggs Institute checklists were used for risk of bias. A random effects meta-analysis was performed and the certainty of the evidence was assessed using the GRADE tool. 

RESULTS: Eight studies with some impact on phonological awareness were reviewed. The risk of bias was low and moderate. The certainty of the evidence was low for randomized trials and very low for non-randomised trials. Comparison of pre- and post-therapy on the Preschool Literacy Test (TOPEL) showed that children with ASD improved phonological awareness, with a mean difference between baseline and post-therapy of 6.21 (95% CI = 3.75-8.67; I2 = 0%). 

CONCLUSION: Shared reading and software activities with words and phrases can alter phonological awareness. These results support further research with larger samples and a detailed description of the intervention to observe its effectiveness in phonological awareness.
AN  - 38747755
AU  - Santos,
AU  - Mfpd
AU  - Aprigio,
AU  - L.
AU  - C.
AU  - S.
AU  - Lima,
AU  - Jvsb
AU  - Miranda,
AU  - F.
AU  - D.
AU  - F.
AU  - Araujo,
AU  - C.
AU  - M.
AU  - Taveira,
AU  - K.
AU  - V.
AU  - M.
AU  - Salgado-Azoni,
AU  - C.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1590/2317-1782/20242022336en
L1  - internal-pdf://1410164344/Santos-2024-Impact of reading intervention on.pdf
PY  - 2024
SP  - e20220336
T2  - Codas
TI  - Impact of reading intervention on the phonological awareness of children with autism spectrum disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1590%2f2317-1782%2f20242022336en
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11104507/pdf/codas-36-3-e20220336.pdf
VL  - 36
ER  -
TY  - JOUR
AB  - Children and adolescents with Autism Spectrum Disorder (ASD) often experience challenges in emotion regulation (ER) and emotion dysregulation (ED) which can interfere with their adaptive functioning. This study aimed to systematically review and meta-analyze the evidence on ER/ED in children and/or adolescents with ASD, examining its relationship with the following variables: internalizing and externalizing symptoms, cognitive function and social skills, and the effectiveness of non-pharmacological interventions addressing ER difficulties. Both electronic and manual searches were conducted to identify potential studies. Fifty-five studies were included in the meta-analysis. A statistically significant between-group difference was found, suggesting greater ER/ED challenges in the ASD group. Also, the ASD group showed more maladaptive ER strategies and fewer adaptive ER strategies compared to the non-ASD participants. Additionally, more severe ASD and poorer social skills were associated with greater ED and poorer ER skills, respectivelly. Furthermore, there was a significant correlation between internalizing symptomatology and both adaptive and maladaptive ER strategies. Studies of non-pharmacological interventions showed significant improvement in both ER and ED. These results imply that assessing ER/ED in children and adolescents with ASD should be part of the evaluation process, and it should also be a focal point for intervention in this population.
AN  - 38401510
AU  - Restoy,
AU  - D.
AU  - Oriol-Escude,
AU  - M.
AU  - Alonzo-Castillo,
AU  - T.
AU  - Magan-Maganto,
AU  - M.
AU  - Canal-Bedia,
AU  - R.
AU  - Diez-Villoria,
AU  - E.
AU  - Gisbert-Gustemps,
AU  - L.
AU  - Setien-Ramos,
AU  - I.
AU  - Martinez-Ramirez,
AU  - M.
AU  - Ramos-Quiroga,
AU  - J.
AU  - A.
AU  - Lugo-Marin,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.cpr.2024.102410
L1  - internal-pdf://3056485766/1-s2.0-S027273582400031X-main.cleaned.pdf
PY  - 2024
SP  - 102410
T2  - Clinical Psychology Review
TI  - Emotion regulation and emotion dysregulation in children and adolescents with Autism Spectrum Disorder: A meta-analysis of evaluation and intervention studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38401510
UR  - https://www.sciencedirect.com/science/article/pii/S027273582400031X?via%3Dihub
VL  - 109
ER  -
TY  - JOUR
AB  - There is increasing interest in the use of omega-3 supplements to reduce aggressive behavior. This meta-analysis summarizes findings from 29 RCTs (randomized controlled trials) on omega-3 supplementation to reduce aggression, yielding 35 independent samples with a total of 3918 participants. Three analyses were conducted where the unit of analysis was independent samples, independent studies, and independent laboratories. Significant effect sizes were observed for all three analyses (g = 0.16, 0.20, 0.28 respectively), averaging 0.22, in the direction of omega-3 supplementation reducing aggression. There was no evidence of publication bias, and sensitivity analyses confirmed findings. Moderator analyses were largely non-significant, indicating that beneficial effects are obtained across age, gender, recruitment sample, diagnoses, treatment duration, and dosage. Omega-3 also reduced both reactive and proactive forms of aggression, particularly with respect to self-reports (g = 0.27 and 0.20 respectively). It is concluded that there is now sufficient evidence to begin to implement omega-3 supplementation to reduce aggression in children and adults - irrespective of whether the setting is the community, the clinic, or the criminal justice system. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2025-24331-001
AU  - Raine,
AU  - Adrian
AU  - Brodrick,
AU  - Lia
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.avb.2024.101956
L1  - internal-pdf://2323317465/1-s2.0-S1359178924000466-main.pdf
PY  - 2024
SP  - 1-9
T2  - Aggression and Violent Behavior
TI  - Omega-3 supplementation reduces aggressive behavior: A meta-analytic review of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.1016%2fj.avb.2024.101956
UR  - https://www.sciencedirect.com/science/article/pii/S1359178924000466?via%3Dihub
VL  - 78
ER  -
TY  - JOUR
AB  - Background: The cognitive development of children and adolescents is crucial for their academic success and overall well-being. Physical activity has been linked to improved cognitive performance, but the specific effects of football training on cognitive function in this population remain unclear. This meta-analytic review aimed to comprehensively evaluate the impact of football training on cognitive performance in children and adolescents. 

Methods: Literature was searched through PubMed, PsycINFO, SPORTDiscus, Embase, and Web of Science. Eligible studies were randomized controlled trials (RCTs) or crossover designs assessing cognitive performance following football training interventions. Outcome measures included attention, inhibitory control, and working memory. Data synthesis and meta-analysis were performed to determine the overall effect sizes. 

Results: Twelve studies were included in the meta-analysis, comprising 1,574 children and 94 adolescents. Football training demonstrated moderate, statistically significant effects on attention (Hedges&#039; g = -0.77, p = 0.01), inhibitory control (Hedges&#039; g = -0.67, p = 0.02), and working memory (Hedges&#039; g = -0.44, p = 0.03). The findings suggest that football training positively influences cognitive performance in children and adolescents. 

Conclusion: Football training holds promise for enhancing cognitive function in children and adolescents, particularly in attention, inhibitory control, and working memory. Theoretical frameworks emphasizing environmental enrichment, cardiovascular fitness, and cognitive component skills help elucidate the underlying mechanisms. Future research should explore how football training compares to other sports and assess whether integrative drills that combine cognitive elements with skill practice offer greater cognitive benefits than skill training alone. These insights support the inclusion of football in educational programs to foster cognitive development.
AN  - 39600599
AU  - Mao,
AU  - F.
AU  - Yin,
AU  - A.
AU  - Zhao,
AU  - S.
AU  - Fang,
AU  - Q.
DB  - November 2024.enl
DO  - /10.3389/fpsyg.2024.1449612
L1  - internal-pdf://3353052995/Mao-2024-Effects of football training on cogni.pdf
PY  - 2024
SP  - 1449612
T2  - Frontiers in Psychology
TI  - Effects of football training on cognitive performance in children and adolescents: a meta-analytic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffpsyg.2024.1449612
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11588498/pdf/fpsyg-15-1449612.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - **Background**: A range of school‐based interventions are effective in improving student diet and physical activity (e.g. school food policy interventions and classroom physical activity interventions), and reducing obesity, tobacco use and/or alcohol use (e.g. tobacco control programmes and alcohol education programmes). However, schools are frequently unsuccessful in implementing such evidence‐based interventions.**Objectives**: The primary review objective is to evaluate the effectiveness of strategies aiming to improve school implementation of interventions to address students&#039; (aged 5 to 18 years) diet, physical activity, obesity, tobacco use and/or alcohol use. The secondary objectives are to:1. determine whether the effects are different based on the characteristics of the intervention including school type and the health behaviour or risk factor targeted by the intervention;2. describe any unintended consequences and adverse effects of strategies on schools, school staff or students; and3. describe the cost or cost‐effectiveness of strategies.**Search methods**: We searched CENTRAL, MEDLINE (Ovid), Embase (Ovid), five additional databases, the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP), and the US National Institutes of Health registry (clinicaltrials.gov). The latest search was between 1 May 2021 and 30 June 2023 to identify any relevant trials published since the last published review.**Selection criteria**: We defined &#039;implementation&#039; as the use of strategies to adopt and integrate evidence‐based health interventions and to change practice patterns within specific settings. We included any randomised controlled trial (RCT) or cluster‐RCT conducted on any scale, in a school setting, with a parallel control group that compared a strategy to improve the implementation of policies or practices to address diet, physical activity, obesity, tobacco use and/or alcohol use by students (aged 5 to 18 years) to no active implementation strategy (i.e. no intervention, inclusive of usual practice, minimal support) or a different implementation strategy.**Data collection and analysis**: We used standard Cochrane methods. Given the large number of outcomes reported, we selected and included the effects of a single outcome measure for each trial for the primary outcome using a decision hierarchy (i.e. continuous over dichotomous, most valid, total score over subscore). Where possible, we calculated standardised mean differences (SMDs) to account for variable outcome measures with 95% confidence intervals (CI). We conducted meta‐analyses using a random‐effects model. Where we could not combine data in meta‐analysis, we followed recommended Cochrane methods and reported results in accordance with &#039;Synthesis without meta‐analysis&#039; (SWiM) guidelines. We conducted assessments of risk of bias and evaluated the certainty of evidence (GRADE approach) using Cochrane procedures.**Main results**: We included an additional 14 trials in this update, bringing the total number of included trials in the review to 39 trials with 83 trial arms and 6489 participants. Of these, the majority were conducted in Australia and the USA (n = 15 each). Nine were RCTs and 30 were cluster‐RCTs. Twelve trials tested strategies to implement healthy eating practices; 17 physical activity, two tobacco, one alcohol, and seven a combination of risk factors. All trials used multiple implementation strategies, the most common being educational materials, educational meetings, and education outreach visits, or academic detailing. Of the 39 included trials, we judged 26 as having high risks of bias, 11 as having some concerns, and two as having low risk of bias across all domains. Pooled analyses found, relative to a control (no active implementation strategy), the use of implementation strategies probably results in a large increase in the implementation of interventions in schools (SMD 0.95, 95% CI 0.71, 1.19; I2 = 78%; 30 trials, 4912 participants; moderate‐certainty evidence). This is equivalent to a 0.76 increase in the implementation of seven physical activity intervention components when the SMD is re‐expressed using an implementation measure from a selected included trial. Subgroup analyses by school type and targeted health behaviour or risk factor did not identify any differential effects, and only one study was included that was implemented at scale. Compared to a control (no active implementation strategy), no unintended consequences or adverse effects of interventions were identified in the 11 trials that reported assessing them (1595 participants; moderate‐certainty evidence). Nine trials compared costs between groups with and without an implementation strategy and the results of these comparisons were mixed (2136 participants; low‐certainty evidence). A lack of consistent terminology describing implementation strategies was an important limitation of the review. **Authors&#039; conclusions**: We found the use of implementation strategies probably results in large increases in implementation of interventions targeting healthy eating, physical activity, tobacco and/or alcohol use. While the effectiveness of individual implementation strategies could not be determined, such examination will likely be possible in future updates as data from new trials can be synthesised. Such research will further guide efforts to facilitate the translation of evidence into practice in this setting. The review will be maintained as a living systematic review.
AU  - Lee,
AU  - D.,
AU  - O&#039;Brien,
AU  - K.,
AU  - McCrabb,
AU  - S.,
AU  - Wolfenden,
AU  - L.,
AU  - Tzelepis,
AU  - F.,
AU  - Barnes,
AU  - C.,
AU  - Yoong,
AU  - S.,
AU  - Bartlem,
AU  - K.,
AU  - Hodder,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1002/14651858.CD011677.pub4
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Strategies for enhancing the implementation of school‐based policies or practices targeting diet, physical activity, obesity, tobacco or alcohol use
ER  -
TY  - JOUR
AB  - Family therapy for eating disorders (ED) is well-established and represents the treatment choice for ED in children and adolescents according to guidelines, with cognitive behavior therapy (CBT) as a second line treatment. There is limited knowledge about how these treatments work in routine clinical care. The goal of the present meta-analysis is to investigate the effectiveness of family therapy and CBT for various EDs in children and adolescents when carried out in routine clinical care. Ovid MEDLINE, Embase OVID, and PsycINFO were searched for articles published until December 2023. The outcome of family therapy and CBT, methodological quality, risk of bias, and moderators of treatment outcome were examined and benchmarked by meta-analytically comparing with ED efficacy studies. Forty-four effectiveness studies comprising 3251 family therapy or CBT patients were included. Large to very large within-group effect sizes (ES) were found for ED-psychopathology (0.80) and weight measures for AN (1.64) at post treatment. The attrition rate was 15%. Risk of bias was considerable. Moderate to large ES were found for family therapy and CBT, respectively. The benchmarking analysis showed that effectiveness studies had comparable ESs to efficacy studies (0.80 and 0.84 for the ED-psychopathology at post treatment). The findings support family therapy and CBT for ED in children and adolescents as effective treatments when delivered in routine clinical care, with effects comparable with those found in efficacy studies. The evidence needs to be interpreted with caution because of the risk of bias in a high proportion of studies.PROSPERO [CRD42023441794].
AN  - 39190154
AU  - Wergeland,
AU  - G.
AU  - J.
AU  - Ghaderi,
AU  - A.
AU  - Fjermestad,
AU  - K.
AU  - Enebrink,
AU  - P.
AU  - Halsaa,
AU  - L.
AU  - Njardvik,
AU  - U.
AU  - Riise,
AU  - E.
AU  - N.
AU  - Vorren,
AU  - G.
AU  - Ost,
AU  - L.
AU  - G.
DB  - August 2024.enl
DO  - /10.1007/s00787-024-02544-1
L1  - internal-pdf://3815072106/Wergeland-2024-Family therapy and cognitive be.pdf
PY  - 2024
SP  - 27
T2  - European Child &amp; Adolescent Psychiatry
TI  - Family therapy and cognitive behavior therapy for eating disorders in children and adolescents in routine clinical care: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs00787-024-02544-1
UR  - https://link.springer.com/content/pdf/10.1007/s00787-024-02544-1.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - Mental health problems are the leading cause of childhood disability worldwide, resulting in poor outcomes for children and young people that persist into adulthood. It is essential that those young people most at risk of developing mental health problems receive effective preventative interventions. Whilst there have been a number of systematic reviews which have examined the effectiveness of secondary prevention interventions for specific groups of children and young people, or to address identified mental health concerns, no review has engaged with the breadth of this literature. We conducted a systematic review of systematic reviews to map this complex field of secondary preventative interventions and identify effective interventions to prevent mental health problems in children and adolescents aged 3-17 years. The review protocol was registered on PROSPERO. We searched five electronic databases from inception to February 2023. The certainty of the evidence was appraised using the AMSTAR 2. We included 49 unique systematic reviews each including between 2 and 249 (mean 34) unique studies; the majority of which were reviews which included only or mostly randomised controlled trials (70%). The reviews examined selective interventions (defined as interventions which are delivered to sub-group populations of young people at increased risk of mental health problems) (n = 22), indicated interventions (defined as interventions which target young people who are found to have pre-clinical symptoms) (n = 15) or a synthesis of both (n = 12). The certainty of the evidence in the reviews was rated as high, (n = 12) moderate (n = 5), low (n = 9) and critically low (n = 23). We found evidence to support both selective and indicated interventions in a range of populations and settings, with most of this evidence available for children and young people in their mid-years (6-10 years) and early adolescence (11-13 years). There was a large body of evidence suggesting that resilience enhancing, cognitive behaviour therapy-based and psychoeducational interventions for children who experience adversity, or those with subclinical externalising problems may offer promise. Early selective interventions for a subpopulation of children and young people who have experienced adversity which combines risk reduction and resilience enhancing approaches directed at children and their families may be effective at reducing mental health problems.
AN  - 38884876
AU  - McGovern,
AU  - R.
AU  - Balogun-Katung,
AU  - A.
AU  - Artis,
AU  - B.
AU  - Bareham,
AU  - B.
AU  - Spencer,
AU  - L.
AU  - Alderson,
AU  - H.
AU  - Brown,
AU  - E.
AU  - Brown,
AU  - J.
AU  - Lingam,
AU  - R.
AU  - McArdle,
AU  - P.
AU  - Newham,
AU  - J.
AU  - J.
AU  - Wojciechowska,
AU  - A.
AU  - Rankin,
AU  - J.
AU  - Redgate,
AU  - S.
AU  - Thomason,
AU  - P.
AU  - Kaner,
AU  - E.
DB  - Juni 24.enl
DO  - /10.1007/s10935-024-00785-z
L1  - internal-pdf://0017591843/McGovern-2024-The Effectiveness of Preventativ.pdf
PY  - 2024
SP  - 17
T2  - Jurnal de Prevenire
TI  - The Effectiveness of Preventative Interventions to Reduce Mental Health Problems in at-risk Children and Young People: A Systematic Review of Reviews
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs10935-024-00785-z
UR  - https://link.springer.com/content/pdf/10.1007/s10935-024-00785-z.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - BACKGROUND: The evidence of treatment options&#039; efficacy on acute bipolar manic episodes is relatively less in youths than adults. We aimed to compare and rank the drug&#039;s efficacy, acceptability, tolerability, and safety for acute mania in children and adolescents. 

METHOD: We systematically reviewed the double-blinded, randomized controlled trials (RCTs) comparing drugs or placebo for acute manic episodes of bipolar disorder in children and adolescents using PRISMA guidelines. We searched PubMed/MEDLINE, EMBASE, Web of Science, EBSCO, Scopus, the Cochrane Central Register of Controlled Trials, and https://clinicaltrials.gov from inception until November 20, 2022. Response to treatment was the primary outcome, and random-effects network meta-analyses were conducted (PROSPERO 2022: CRD42022367455). 

RESULTS: Of 10,134 citations, we included 15 RCTs, including 2372 patients (47 % female), 15 psychotropic drugs, and the placebo. Risperidone 0.5-2.5 mg/day, aripiprazole 30 mg/day olanzapine, quetiapine 400 mg/day, quetiapine 600 mg/day, asenapine 5 mg/day, asenapine 10 mg, ziprasidone, and aripiprazole 10 mg were found to be effective (in comparison with placebo) in children and adolescents, respectively (tau&lt;sup&gt;2&lt;/sup&gt; = 0.0072, I&lt;sup&gt;2&lt;/sup&gt; = 10.2 %). The tolerability of aripiprazole 30 mg/day was lower than risperidone 0.5-2.5 mg/day and olanzapine. Oxcarbazepine had the highest discontinuation due to the adverse effects risk ratio. LIMITATIONS: Efficacy ranking of the treatments could be performed by evaluating relatively few RCT results, and only monotherapies were considered. 

CONCLUSIONS: Efficacy, acceptability, tolerability, and safety are changing with the doses of antipsychotics for children and adolescents with acute bipolar manic episodes. Drug selection and optimum dosage should be carefully adjusted in children and adolescents.
AN  - 38211745
AU  - Tural
AU  - Hesapcioglu,
AU  - S.
AU  - Kasak,
AU  - M.
AU  - Abursu,
AU  - H.
AU  - Kafali,
AU  - S.
AU  - Ceylan,
AU  - M.
AU  - F.
AU  - Akyol,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2024.01.067
L1  - internal-pdf://1210486533/1-s2.0-S0165032724000776-main.cleaned.pdf
PY  - 2024
SP  - 438-451
T2  - Journal of Affective Disorders
TI  - A systematic review and network meta-analysis on comparative efficacy, acceptability, and safety of treatments in acute bipolar mania in youths
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38211745
UR  - https://www.sciencedirect.com/science/article/pii/S0165032724000776?via%3Dihub
VL  - 349
ER  -
TY  - JOUR
AB  - BACKGROUND: Cognitive-Behavior Therapy (CBT) is the validated non-pharmacological treatment for chronic pain in pediatric patients. While some suggested CBT were comparable to the usual care in reducing children&#039;s functional abdominal pain. This meta-analysis was designed to systematically review the literature for RCTs that investigated the efficacy of CBT in children with functional abdominal pain (FAP). 

METHODS: PubMed, Embase, and the Cochrane library were searched for papers published up to October 2022. Studies applying different CBT delivery methods (in-person, web-based, phone-based) were included in this meta-analysis to evaluate the comprehensive effectiveness of CBT compared with usual care. Weighted and standardized mean difference with the 95% confidence intervals were used for the synthesis of the results. Primary outcome was the decrease of functional disability inventory (FDI) and the secondary outcomes were the decrease of severity in pain intensity, depression, anxiety, gastrointestinal symptoms, and improvement in physical quality of life (QoL). 

RESULTS: A total of 10 RCTs with 1187 children were included in the final analysis. The results showed that CBT resulted in better effect in reducing functional disability inventory (SMD=-2.282, 95%CI: -4.537 to -0.027, P = 0.047), pain intensity (SMD=-0.594, 95%CI: -1.147 to -0.040, P = 0.036), and improving QoL (SMD = 14.097, 95%CI: 0.901 to 27.292, P = 0.036) compared with the control groups. Comparable effects were observed in the severity of depression (SMD=-0.493, 95%CI: -1.594 to 0.608, P = 0.380), anxiety (SMD=-0.062, 95%CI: -0.640 to 0.517, P = 0.835), and gastrointestinal symptoms (SMD=-1.096 95%CI: -2.243 to 0.050, P = 0.061) between CBT and usual treatment. 

CONCLUSIONS: We observed the differences in post-treatment FAP and pain intensity for children receiving CBT compared with children receiving treatment as usual. CBT in the setting of FAP demonstrates promising developments and highlights the need for future research.
AN  - 38310252
AU  - Huang,
AU  - X.
AU  - Jia,
AU  - N.
AU  - Zhang,
AU  - Y.
AU  - Hao,
AU  - Y.
AU  - Xiao,
AU  - F.
AU  - Sun,
AU  - C.
AU  - Cui,
AU  - X.
AU  - Wang,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1186/s12876-024-03120-2
L1  - internal-pdf://3886361540/Huang-2024-Effect of cognitive-behavior therap.pdf
PY  - 2024
SP  - 62
T2  - BMC Gastroenterology
TI  - Effect of cognitive-behavior therapy for children with functional abdominal pain: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38310252
UR  - https://bmcgastroenterol.biomedcentral.com/counter/pdf/10.1186/s12876-024-03120-2.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - Violence against children (VAC) in the home, or by household members, is a human rights and social problem with long-lasting consequences for individuals and society. Global policy instruments like the INSPIRE package have proposed strategies to prevent VAC, including Implementation and enforcement of laws, Norms and values, Safe environments, Parent and caregiver support, Income and economic strengthening, Response and support services, and Education and life skills. This systematic review of reviews aimed to synthesize the recent evidence base (i.e., published since 2000) for each INSPIRE strategy to reduce VAC in the home or by household members. We searched four databases using controlled vocabularies and keywords and searched for additional records in prior reviews of reviews. A total of 67 studies were included in this review, including literature reviews, meta-analyses, systematic reviews, and other types of reviews. We found extensive evidence supporting the effectiveness of parent and caregiver support interventions. However, reviews on other INSPIRE strategies were scarce. We also found a vast underrepresentation of samples from low- and- middle-income countries, children with disabilities, and families affected by forced displacement and conflict. In sum, this systematic review suggests that there are several promising strategies to prevent VAC (e.g., home visiting and parent education), but further research is necessary to strengthen the current body of evidence and effectively inform the implementation and scale-up of evidence-based interventions to protect children from violence globally.
AN  - 38682572
AU  - Cuartas,
AU  - J.
AU  - Salazar,
AU  - A.
AU  - Backhaus,
AU  - S.
AU  - Little,
AU  - M.
AU  - T.
AU  - McCoy,
AU  - D.
AU  - Yoshikawa,
AU  - H.
AU  - Bass,
AU  - M.
AU  - Metheny,
AU  - N.
AU  - Knaul,
AU  - F.
DB  - April 24.enl
DO  - /10.1177/15248380241247018
L1  - internal-pdf://0590620321/cuartas-et-al-2024-strategies-to-prevent-viole.pdf
PY  - 2024
SP  - 15248380241247018
T2  - Trauma Violence &amp; Abuse
TI  - Strategies to Prevent Violence Against Children in the Home: A Systematic Review of Reviews
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1177%2f15248380241247018
ER  -
TY  - JOUR
AB  - Aims: This systematic review and meta-analysis aimed to assess the efficacy of NMDA antagonists in ASD (Autism Spectrum Disorder) on the core (communication and social interaction, repetitive behavior) and associated symptoms (irritability) of ASD, as well as their safety. 

Methods: PubMed, CENTRAL, CINHAL, EMBASE, and PsycINFO databases were searched until November 2023. Two authors independently selected the studies and extracted data. Randomized controlled trials assessing the efficacy of NMDA receptor antagonists in participants with ASD aged &lt;18 years were included. The quality of the studies was assessed using the Risk of Bias-2 tool. A random-effect meta-analysis model was used to calculate standardized mean differences (SMD) or odds ratios (OR) using meta package in R. 

Results: This systematic review included ten studies (588 participants). Most studies did not report scales assessing core symptoms of ASD. Meta-analysis of efficacy on ASD core symptoms included three studies (248 participants). NMDA antagonists were not superior to placebo [SMD = 0.29; CI 95% (-1,94; 1.35); I-2 = 0%]. NMDA antagonists was not superior to placebo concerning response (four studies, 189 participants) [OR = 2.4; CI 95% (0.69; 8.38); I-2 = 35%]. Meta-analysis of efficacy on irritability included three studies (186 participants); NMDA antagonists were not superior to placebo [MD irritability = -1.94; CI 95% (-4.66; 0.77); I-2 = 0%]. Compared with placebo, significantly more participants in the NMDA antagonist group reported at least one adverse event (five studies, 310 participants) [OR = 2.04; CI 95% (1.17; 3.57); I-2 = 0%]. 

Conclusion: Current evidence does not support the effectiveness of NMDA antagonists in the treatment of ASD symptoms or irritability. Further research is needed due to the limited and low quality data available.
AN  - WOS:001284689600001
AU  - Dessus-Gilbert,
AU  - M.
AU  - L.
AU  - Nourredine,
AU  - M.
AU  - Zimmer,
AU  - L.
AU  - Rolland,
AU  - B.
AU  - Geoffray,
AU  - M.
AU  - M.
AU  - Auffret,
AU  - M.
AU  - Jurek,
AU  - L.
DB  - September 2024.enl
DO  - 10.3389/fphar.2024.1395867
L1  - internal-pdf://3000390075/Dessus-Gilbert-2024-NMDA antagonist agents for.pdf
PY  - 2024
SP  - 13
T2  - Frontiers in Pharmacology
TI  - NMDA antagonist agents for the treatment of symptoms in autism spectrum disorder: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001284689600001
UR  - https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1395867/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Objective: Young people with post-traumatic stress disorder experience difficulties in social and interpersonal domains. We examined whether the best-evidenced treatments of PTSD for children and young people (Trauma-focussed Cognitive Behavioural Therapy or Eye Movement Desensitisation and Reprocessing; aged 5&ndash;25) improve social or interpersonal factors in randomised controlled trials, compared to a comparator condition.

Method: The review was preregistered on PROSPERO (CRD42023455615; 18th August 2023). Web of Science Core Collection, EMBASE, CINAHL, Pubmed, PsycINFO, Cochrane Central Register of Controlled Trials and PTSDPubs were searched, and data were extracted for social and interpersonal outcomes post treatment. A random effect meta-analysis was conducted to obtain between-group pooled effect size estimates.

Results: The search resulted in 792 studies, of which 17 met our inclusion criteria (N&thinsp;=&thinsp;2498). Our meta-analysis included 13 studies which investigated social skills and functioning, revealing a small but non-significant effect favouring the evidence-based treatment versus comparison (g&thinsp;=&thinsp;.20, 95% CI [&minus;0.03, 0.44], p&thinsp;=&thinsp;.09). We narratively synthesised six studies which reported other social-related outcomes (e.g. perceptions of social support), and four out of six reported improved social domain outcomes for the evidence-based PTSD treatment condition. There was a large amount of heterogeneity, with no evidence that this could be explained by moderators.

Conclusion: Few trials report on social and interpersonal outcomes, and where they are reported the evidence is mixed. It may be that trauma-focused therapies for PTSD need to be adapted in some circumstances, so that they address social and interpersonal deficits often seen in children and young people with PTSD..
AN  - 39450446
AU  - Phillips,
AU  - A.
AU  - R.
AU  - Halligan,
AU  - S.
AU  - L.
AU  - Bailey,
AU  - M.
AU  - Birkeland,
AU  - M.
AU  - S.
AU  - Lavi,
AU  - I.
AU  - Meiser-Stedman,
AU  - R.
AU  - Oram,
AU  - H.
AU  - Robinson,
AU  - S.
AU  - Sharp,
AU  - T.
AU  - H.
AU  - Hiller,
AU  - R.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1080/20008066.2024.2415267
L1  - internal-pdf://3612278998/Phillips-2024-Systematic review and meta-analy.pdf
PY  - 2024
SP  - 2415267
T2  - European Journal of Psychotraumatology
TI  - Systematic review and meta-analysis: do best-evidenced trauma-focused interventions for children and young people with PTSD lead to changes in social and interpersonal domains?
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1080%2f20008066.2024.2415267
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11514400/pdf/ZEPT_15_2415267.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Background
When sufficient maternal milk is not available, donor human milk or formula are the alternative forms of enteral nutrition for very preterm or very low‐birthweight (VLBW) infants. Donor human milk may retain the non‐nutritive benefits of maternal milk and has been proposed as a strategy to reduce the risk of necrotising enterocolitis (NEC) and associated mortality and morbidity in very preterm or VLBW infants.

Objectives
To assess the effectiveness of donor human milk compared with formula for preventing NEC and associated morbidity and mortality in very preterm or VLBW infants when sufficient maternal milk is not available.

Search methods
We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, the Maternity and Infant Care (MIC) database, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL), from the earliest records to February 2024. We searched clinical trials registries and examined the reference lists of included studies.

Selection criteria
Randomised or quasi‐randomised controlled trials comparing feeding with donor human milk versus formula in very preterm (&lt; 32 weeks&#039; gestation) or VLBW (&lt; 1500 g) infants.

Data collection and analysis
Two review authors evaluated the risk of bias in the trials, extracted data, and synthesised effect estimates using risk ratio, risk difference, and mean difference, with associated 95% confidence intervals. The primary outcomes were NEC, late‐onset invasive infection, and all‐cause mortality before hospital discharge. The secondary outcomes were growth parameters and neurodevelopment. We used the GRADE approach to assess the certainty of the evidence for our primary outcomes.

Main results
Twelve trials with a total of 2296 infants fulfilled the inclusion criteria. Most trials were small (average sample size was 191 infants). All trials were performed in neonatal units in Europe or North America. Five trials were conducted more than 40 years ago; the remaining seven trials were conducted in the year 2000 or later. Some trials had methodological weaknesses, including concerns regarding masking of investigators and selective reporting.

Meta‐analysis showed that donor human milk reduces the risk of NEC (risk ratio (RR) 0.53, 95% confidence interval (CI) 0.37 to 0.76; I&sup2; = 4%; risk difference (RD) &minus;0.03, 95% CI &minus;0.05 to &minus;0.01; 11 trials, 2261 infants; high certainty evidence). Donor human milk probably has little or no effect on late‐onset invasive infection (RR 1.12, 0.95 to 1.31; I&sup2; = 27%; RD 0.03, 95% CI &minus;0.01 to &minus;0.07; 7 trials, 1611 infants; moderate certainty evidence) or all‐cause mortality (RR 1.00, 95% CI 0.76 to 1.31; I&sup2; = 0%; RD &minus;0.00, 95% CI &minus;0.02 to 0.02; 9 trials, 2116 infants; moderate certainty evidence).

Authors&#039; conclusions
The evidence shows that donor human milk reduces the risk of NEC by about half in very preterm or VLBW infants. There is probably little or no effect on late‐onset invasive infection or all‐cause mortality before hospital discharge.
AN  - CD002971
AU  - Quigley,
AU  - M.
AU  - Embleton,
AU  - N.
AU  - D.
AU  - Meader,
AU  - N.
AU  - McGuire,
AU  - W.
DB  - September 2024.enl
DO  - 10.1002/14651858.CD002971.pub6
KW  - *Enterocolitis, Necrotizing [epidemiology, prevention &amp; control]
KW  - *Infant, Very Low Birth Weight
KW  - *Milk, Human
KW  - Bias
KW  - Enteral Nutrition [methods]
KW  - Humans
KW  - Infant Formula
KW  - Infant, Extremely Premature
KW  - Infant, Newborn
KW  - Infant, Premature
KW  - Infant, Premature, Diseases [mortality, prevention &amp; control]
KW  - Randomized Controlled Trials as Topic
N1  - [Neonatal]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Donor human milk for preventing necrotising enterocolitis in very preterm or very low‐birthweight infants
UR  - https://doi.org//10.1002/14651858.CD002971.pub6
ER  -
TY  - JOUR
AB  - BACKGROUND: Despite evidence suggesting that age moderates the response to preventative treatment for those at clinical high risk of psychosis (CHR-P), no meta-analysis has assessed the effectiveness of preventative interventions for CHR-P children and adolescents. Our aim was to synthesise evidence assessing preventative interventions on a wide range of mental health outcomes for CHR-P children and adolescents. 

METHOD: A systematic search was conducted on Ovid MEDLINE, Pubmed, APA PsycInfo and Web of Science until June 2024 (PROSPERO: CRD42023406696). Intervention studies that had a mean participant age of under 18 years old that reported on mental health outcomes for CHR-P participants were selected. A meta-analysis was conducted for independent studies reporting the effectiveness of interventions on different outcomes (transition to psychosis, attenuated positive, negative and total prodromal psychotic symptoms, depressive symptoms and global functioning) compared to control conditions of no intervention or placebo. Evidence from other studies was also reported narratively. 

RESULTS: Twenty-four studies and 1319 CHR-P children and adolescents were included. Compared to no intervention or placebo, preventative interventions were effective for positive symptoms (SMD = 0.379, p = .022, 95% CI 0.055, 0.703), negative symptoms (SMD = 0.583, p = .004, 95% CI 0.187, 0.980), total symptoms (SMD = 0.677, p = .002, 95% CI 0.249, 1.105) and functioning (SMD = 0.944, p = .038, 95% CI 0.052, 1.836) but not reducing transition to psychosis or depressive symptoms. 

CONCLUSIONS: There are disparities in the effectiveness of preventative interventions for different outcomes, with transition to psychosis not being the only relevant outcome. Differences in the efficacy of preventative interventions emerged between CHR-P children and adolescents versus adults.
AN  - 39688301
AU  - Frearson,
AU  - G.
AU  - de
AU  - Otazu
AU  - Olivares,
AU  - J.
AU  - Catalan,
AU  - A.
AU  - Aymerich,
AU  - C.
AU  - de
AU  - Pablo,
AU  - G.
AU  - S.
DB  - Desember 2024.enl
DO  - /10.1111/camh.12755
L1  - internal-pdf://3488939202/Child Adoles Ment Health - 2024 - Frearson - R.pdf
PY  - 2024
SP  - 17
T2  - Child &amp; Adolescent Mental Health
TI  - Review: Efficacy of preventative interventions for children and adolescents at clinical high risk of psychosis - a systematic review and meta-analysis of intervention studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1111%2fcamh.12755
VL  - 17
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering om effektene av Depresjonsmestring for ungdom (DU). Artikkelen er en revisjon av tidligere evalueringer av DU i Ungsinn (Wergeland, Skotheim &amp; Kvello, 2016; Kvello, 2013), og omarbeidet i henhold til Ungsinn sine nye kriterier og prosedyrer for vurdering og klassifisering av tiltak (Martinussen mfl., 2019). DU er et tiltak på 10 sesjoner rettet mot ungdom i alderen 14&ndash;20 år med lett til moderat grad av depresjon eller depresjonssymptomer. I siste versjon av tiltaket er navnet endret til DU &ndash; Mestringskurs for ungdom. Tiltaket er utviklet av Trygve Arne Børve, og implementeres i Norge gjennom studieforbundet AOF. Hensikten med denne artikkelen er å undersøke om DU er virksomt benyttet i vanlig praksis i Norge. Hovedmålene for DU er å forebygge utvikling av depresjon, redusere symptomer og å forebygge tilbakefall av depresjon. DU følger en fastsatt struktur som er beskrevet i en manual. Gjennom kurset skal deltakerne få en forståelse for sammenhengen mellom tankestil og nedstemthet, kunnskap og ferdigheter til å redusere risikoen for å utvikle depresjon, og utvikle strategier for å mestre nedstemthet.

METODE
Kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline, PsycInfo, NORART Cochrane, Oria, NORA og SweMed, rapporter fra Helsebiblioteket, NICE og Blueprint, samt informasjon gitt fra tiltakseier.

RESULTATER
I denne artikkelen presenteres resultatene fra litteratursøket, en vurdering av kvaliteten på tiltaket og forskningsmetodisk kvalitet på foreliggende effektstudier. I tillegg beskrives implementeringskvalitet, og en oppsummering av effektene fra studiene. DU vurderes som godt beskrevet gjennom en detaljert manual og flere andre dokumenter. Tiltaket har god teoretisk og empirisk forankring gjennom kognitiv atferdsterapi, og det foreligger to norske effektivitetsstudier (&eacute;n pre&ndash;post-studie, og &eacute;n randomisert kontrollert studie (RCT)) med oppfølgingsmålinger opp til tolv måneder etter avsluttet tiltak, samt &eacute;n norsk kvalitativ evaluering. Studiene viser en effekt av tiltaket på nivået av depressive symptomer hos ungdom i løpet av intervensjonsperioden, og effektstørrelsen er liten til moderat. RCT-studien viser ingen gruppeforskjeller ved seks og tolv måneders oppfølging, Studiene ser ut til å inkludere ungdom med alvorlige depressive symptomer (BDI&gt;30), noe som bidrar til usikkerhet rundt effekten av tiltaket for den tiltenkte målgruppen. For å sikre implementeringskvalitet er det utarbeidet en sertifiseringsordning, og i RCT studien evaluerte kursholderne selv i hvilken grad de leverte i henhold til modellbeskrivelsen (modell trofasthet).

KONKLUSJON
DU er et godt beskrevet tiltak, med sterk teoretisk forankring rettet mot en av de hyppigste psykiske lidelsene blant ungdom. De to effektstudiene indikerer at tiltaket har en effekt på depressive symptomer hos ungdom, men det er fortsatt noe usikkert hvorvidt effektene kan tilskrives tiltaket. Tiltaket nærmer seg dokumentasjonsgrad 4, men gitt en del metodiske svakheter i de foreliggende studiene, klassifiseres DU på evidensnivå 3: Tiltak med noe dokumentasjon på effekt.
AU  - Skotheim,
AU  - S.
AU  - Wergeland,
AU  - G.
AU  - J.
AU  - Kvello,
AU  - Ø.
DB  - April 24.enl
DO  - /post_tiltak_arkiv/mestringskurs-for-ungdom-du-3-utg/
L1  - internal-pdf://0461323902/Mestringskurs-for-ungdom-DU-3.-utg.cleaned.pdf
PY  - 2024
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Mestringskurs for ungdom (DU) (3. utg.)
ER  -
TY  - JOUR
AB  - Purpose: Present study investigated the effectiveness of school-based intervention programs on reducing aggression among children and adolescents. 

Method: A thorough search was carried out on 12 electronic databases. Seventeen studies were finalized, and meta-analyses were performed using a random effect model on RevMan software. 

Results: Findings reveal that existing school-based programs have a significant effect on reducing aggression (standardized mean differences = -0.35, 95% confidence interval [-0.53, -0.18], Z = 3.92, p &lt; .001). Furthermore, subgroup analysis found that interventions with a theoretical basis, using a randomized controlled trial (RCT) design, or having a short duration of each session (below 45 min), were more effective than ones without a theoretical basis, using a quasi-experimental design, or having longer session duration (above 45 min) on reducing aggressive behaviors. 

Conclusion: This review provided implications to improve school-based interventions by developing designs based on the guidance of theories and RCT design, as well as limiting session duration.
AN  - WOS:001155648800001
AU  - Shen,
AU  - L.
AU  - Q.
AU  - Jiang,
AU  - S.
AU  - Tan,
AU  - S.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1177/10497315241227147
L1  - internal-pdf://4008203433/shen-et-al-2024-the-effectiveness-of-school-ba.pdf
PY  - 2024
SP  - 21
T2  - Research on Social Work Practice
TI  - The Effectiveness of School-Based Programs on Aggressive Behaviors among Children and Adolescents: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001155648800001
ER  -
TY  - JOUR
AB  - **Objectives**
We conducted this systematic review to synthesize and assess studies employing differential reinforcement interventions implemented in applied settings by educators to address the challenging behavior of individuals with autism.

**Methods**
A total of 17 studies, involving 26 participants with autism, were eligible for inclusion in the review. We systematically reviewed each study to examine key variables, study quality, and study outcomes.

**Results**
Overall, Tau-U calculations suggested a large to a very large change in outcomes for interventions involving differential reinforcement. Tau-U was higher for interventions involving differential reinforcement of alternative behavior and differential reinforcement of low rates of behavior compared to differential reinforcement of other behavior and differential reinforcement of incompatible behavior. Study quality varied, with only three studies meeting all quality indicators.

**Conclusions**
For a majority of participants, differential reinforcement resulted in positive outcomes for individuals with autism in applied settings. We discuss the results and offer preliminary guidance for practice and directions for future research.
AN  - WOS:001331040300001
AU  - Muharib,
AU  - R.
AU  - Walker,
AU  - V.
AU  - L.
DB  - November 2024.enl
DO  - 10.1007/s41252-024-00419-9
L1  - internal-pdf://3983051001/s41252-024-00419-9.cleaned.pdf
PY  - 2024
SP  - 14
T2  - Advances in Neurodevelopmental Disorders
TI  - Differential Reinforcement in Applied Settings for Individuals with Autism: Systematic Literature Review
UR  - &lt;Go to ISI&gt;://WOS:001331040300001
UR  - https://link.springer.com/article/10.1007/s41252-024-00419-9
ER  -
TY  - JOUR
AB  - Background: Given the rising interest in complementary therapeutic strategies for autism spectrum disorder (ASD), this research aims to provide a comprehensive analysis of the impact of animal-assisted activities and therapies (AAAT) on various ASD symptoms.

Methods: A meticulous search of databases, including Scopus and PubMed, was conducted to gather relevant research on AAAT for ASD. This process led to the selection of 45 studies encompassing 1,212 participants. The chosen studies were then subjected to a meta-analysis to evaluate the efficacy of AAAT in alleviating core ASD symptoms.

Results: The meta-analysis revealed significant improvements in several core ASD symptoms due to AAAT. Notably, there were improvements in social communication (MD&thinsp;=&thinsp;&minus;4.96, 95% CI [&minus;7.49, &minus;2.44]), irritability (MD&thinsp;=&thinsp;&minus;2.38, 95% CI [&minus;4.06, &minus;0.71]), hyperactivity (MD&thinsp;=&thinsp;&minus;4.03, 95% CI [&minus;6.17, &minus;1.89]), and different word usage skills (MD&thinsp;=&thinsp;20.48, 95% CI [7.41, 33.55]). However, social awareness (MD&thinsp;=&thinsp;&minus;1.63, 95% CI [&minus;4.07, 0.81]), social cognition (MD&thinsp;=&thinsp;&minus;3.60, 95% CI [&minus;9.36, 2.17]), social mannerisms (MD&thinsp;=&thinsp;&minus;0.73, 95% CI [&minus;2.55, 1.09]), social motivation (MD&thinsp;=&thinsp;&minus;1.21, 95% CI [&minus;2.56, 0.13]), lethargy (MD&thinsp;=&thinsp;&minus;1.12, 95% CI [&minus;3.92, 1.68]), and stereotypical behaviors (MD&thinsp;=&thinsp;&minus;0.23, 95% CI [&minus;1.27, 0.80]) did not significantly improve.

Conclusion: The study demonstrates the potential of AAAT in improving certain core symptoms of ASD, such as social communication, irritability, hyperactivity, and word usage skills. However, the effectiveness of AAAT in other ASD symptom domains remains uncertain. The research is limited by the absence of long-term follow-up data and a high risk of bias in existing studies. Therefore, while the findings indicate the promise of AAAT in specific areas, caution is advised in generalizing its efficacy across all ASD symptoms.
AN  - WOS:001249581800001
AU  - Xiao,
AU  - N.
AU  - K.
AU  - Bagayi,
AU  - V.
AU  - Yang,
AU  - D.
AU  - D.
AU  - Huang,
AU  - X.
AU  - L.
AU  - Zhong,
AU  - L.
AU  - Kiselev,
AU  - S.
AU  - Bolkov,
AU  - M.
AU  - A.
AU  - Tuzankina,
AU  - I.
AU  - A.
AU  - Chereshnev,
AU  - V.
AU  - A.
DB  - Juli 2024.enl
DO  - 10.3389/fvets.2024.1403527
L1  - internal-pdf://3444456437/Xiao-2024-Effectiveness of animal-assisted act.pdf
PY  - 2024
SP  - 19
T2  - Frontiers in Veterinary Science
TI  - Effectiveness of animal-assisted activities and therapies for autism spectrum disorder: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001249581800001
UR  - https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1403527/pdf
VL  - 11
ER  -
TY  - JOUR
AB  - Importance: Digital technology is now widely available for the interventions of autism, but its validity and feasibility remain to be proved. Objective: This study aimed to investigate the effectiveness of digital health interventions (DHIs) in improving core symptoms or intelligence quotient in patients with autism spectrum disorder (ASD). Methods: Three databases including PubMed, Cochrane, and Scopus, were searched on November 15, 2022. Randomized clinical trials that enrolled patients with ASD who received DHIs and a control group without DHI treatment were included. Cochrane risk of bias tool (RoB 2) was applied to assess the risk of bias. Results: A total of 33 studies, involving 1285 participants (658 [51.2%] in DHI groups and 627 [48.8%] in control groups), were analyzed to investigate the differences between DHI groups and control groups. Significantly greater improvements in the overall performance of ASD were observed in the DHI groups compared to the control groups (including active, waitlist, treatment-as-usual, and no treatment) with an effect size of 1.89 (Cohen&rsquo;s d 95% confidence interval [CI]: 1.26&ndash;2.52). Studies with treatment-as-usual, waitlist, and no treatment control demonstrated large effect sizes of Cohen&rsquo;s d 3.41 (95% CI: 0.84&ndash;5.97), Cohen&rsquo;s d 4.27 (95% CI: 1.95&ndash;6.59), and Cohen&rsquo;s d 4.52 (95% CI: 2.98&ndash;6.06) respectively. In contrast, studies with active control revealed insignificant effect sizes (Cohen&rsquo;s d 0.73, 95% CI: 0.12&ndash;1.33). Interpretation: This meta-analysis found significantly greater improvements in core symptoms or intelligence quotient in ASD patients receiving DHIs compared to those in control conditions. ASD patients may benefit from the DHIs and reduce the economic burden.
AN  - WOS:001172923600001
AU  - Wang,
AU  - T.
AU  - Q.
AU  - Ma,
AU  - Y.
AU  - Du,
AU  - X.
AU  - N.
AU  - Li,
AU  - C.
AU  - P.
AU  - Peng,
AU  - Z.
AU  - B.
AU  - Wang,
AU  - Y.
AU  - Zhou,
AU  - H.
DB  - April 24.enl
DO  - 10.1002/ped4.12417
L1  - internal-pdf://2730864395/Pediatric Investigation - 2024 - Wang - Digita.pdf
PY  - 2024
SP  - 13
T2  - Pediatric Investigation
TI  - Digital interventions for autism spectrum disorders: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001172923600001
ER  -
TY  - JOUR
AB  - Social-emotional skills are a growing area of focus for early childhood educators due to their contributions to young children&#039;s school readiness and long-term positive outcomes. Current research also highlights the need to confront biases leading to the overestimation of challenging behaviors in racially and ethnically minoritized children. When enacted into policy and practices, biases and overestimation of challenging behaviors result in disproportional, exclusionary disciplinary practices towards children from racially minoritized and economically marginalized backgrounds in early childhood educational settings. Thus, it is necessary to select and implement social-emotional learning interventions that have been designed for or culturally adapted to meet specific needs of children from these backgrounds. In the present study, we uncovered the characteristics of social-emotional learning (SEL) interventions that have been designed or culturally adapted for racially and ethnically minoritized preschool-aged children (ages 3-5 years). Using Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines with no restrictions on study dates, we conducted a systematic review of the literature. Our results indicate the implementation of culturally adapted SEL programs among preschool-age children from racially and ethnically minoritized backgrounds is in the preliminary stages with only six studies meeting inclusionary criteria. Overall, children demonstrated improved outcomes after participation in SEL programs. There were significant variations in the SEL curricula used. Frequent types of adaptions included reviewing the program from the original intervention, ensuring that the intervention is delivered in children&#039;s home language, and selecting or training qualified implementers.
AN  - WOS:001265903400001
AU  - Albritton,
AU  - K.
AU  - Stuckey,
AU  - A.
AU  - Klatka,
AU  - K.
AU  - Cruz,
AU  - K.
DB  - August 2024.enl
DO  - 10.1016/j.jsp.2024.101344
L1  - internal-pdf://2568578152/1-s2.0-S0022440524000645-main.cleaned.pdf
PY  - 2024
SP  - 20
T2  - Journal of School Psychology
TI  - Systematic review of culturally adapted SEL interventions for racially and ethnically minoritized preschool children
UR  - &lt;Go to ISI&gt;://WOS:001265903400001
VL  - 106
ER  -
TY  - JOUR
AB  - OBJECTIVE: To investigate the effectiveness of a Treatment and Education of Autistic and Related Communication Handicapped Children (TEACCH) intervention in schools for improving independent task performance in children with autism spectrum disorders (ASD). 

METHODS: We screened relevant studies published up to December 2022 from Web of science, ERIC, PsycINFO and other databases using predefined inclusion/exclusion criteria to identify suitable intervention studies for meta-analysis. Tau-U effect sizes were calculated for each A-B comparison extracted from the included experiments. Moderated analyses were conducted to examine the type of intervention (independent variable), intervention target behaviours (dependent variable), participant characteristics, setting characteristics and intervener characteristics. 

RESULTS: A total of 14 studies (38 participants) met the criteria and were included in the meta-analysis. The analysis results showed that TEACCH had a significant intervention effect, and the overall intervention effect size was Tau-U = 0.85[0.77, 0.91]. There were significant differences in the intervention target behaviour variables (p &lt; 0.01), limited variation in the intervention type variables, but no differences in participant characteristics, setting characteristics and intervenor characteristics. 

CONCLUSION: The use of TEACCH is effective in improving independent task completion in children with ASD and provides evidence-based recommendations for its extended use in schools.
AN  - 38380766
AU  - Zhou,
AU  - K.
AU  - Liu,
AU  - X.
AU  - Li,
AU  - S.
AU  - Zhang,
AU  - Y.
AU  - An,
AU  - R.
AU  - Ma,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1111/cch.13234
L1  - internal-pdf://3049876443/Child - 2024 - Zhou - The use of Treatment and.pdf
PY  - 2024
SP  - e13234
T2  - Child: Care, Health &amp; Development
TI  - The use of Treatment and Education of Autistic and Related Communication Handicapped Children in schools to improve the ability of children with autism to complete tasks independently: A single-case meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38380766
VL  - 50
ER  -
TY  - JOUR
AB  - **Objective**: This overview aims to summarize systematic reviews with meta-analyses estimating the effects of school-based depression prevention interventions on depression outcomes. **Method**: We conducted electronic searches (Australian Education Index, Google Scholar, ProQuest Dissertations and Theses A&amp;I, Pubmed, Social Science Premium Collection), hand-searched key journals, and conducted backward and forward citation chasing to identify eligible reviews. Two reviewers independently screened records, assessed full texts for eligibility, and collected data. We narratively summarized review findings and quantified the overlap of primary studies across systematic reviews using Corrected Covered Area. **Results**: We identified 29 eligible systematic reviews with 472 included primary studies overall (Mdn = 35, range = 4-137). Only 177 primary studies (37%) were included in more than one review (Corrected Covered Area = 6%). We rated all reviews as low (10%) or critically low (90%) quality on A Measurement Tool to Assess systematic Reviews-2, and most reviews (86%) at high risk of bias on Risk Of Bias In Systematic reviews. Reviews mostly suggest school-based depression prevention interventions may have modest average positive impacts on depression-related outcomes-both overall and for specific stages of prevention, school levels and student ages, and specific program manuals and intervention types. However, some reviews did not detect effects, and most reviews noted concerns about primary study quality, heterogeneity, and publication bias in this body of evidence. **Conclusions**: School-based depression prevention interventions may be beneficial on average, though existing reviews have important methodological limitations. A living systematic review conducted according to methodological best practice could provide timely, relevant, and rigorous evidence for educational decision making.
AN  - WOS:001385560300001
AU  - Grant,
AU  - S.
AU  - Schweer-Collins,
AU  - M.
AU  - Day,
AU  - E.
AU  - Trevino,
AU  - S.
AU  - D.
AU  - Steinka-Fry,
AU  - K.
AU  - Tanner-Smith,
AU  - E.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1037/ccp0000930
L1  - internal-pdf://0117701318/72f5167c-2bb9-42b4-8587-6389a3ef3d2c.pdf
PY  - 2024
SP  - 20
T2  - Journal of Consulting and Clinical Psychology
TI  - Effectiveness of School-Based Depression Prevention Interventions: An Overview of Systematic Reviews With Meta-Analyses on Depression Outcomes
UR  - &lt;Go to ISI&gt;://WOS:001385560300001
ER  -
TY  - JOUR
AB  - To compare the effects of different exercise training on executive function (EF) in obese or overweight individuals. PubMed, Web of Science, SPORTDiscus, MEDLINE, and CINAHL. The included articles, in English, should have been published from January 2000 to February 2024. All included studies were randomized controlled trials (RCTs) of exercise intervention in overweight or obese populations. The primary outcomes are EFs, which encompass core functions (e.g., inhibitory control, working memory (WM), and cognitive flexibility (CF)) and higher-level functions (e.g., responding, planning, and problem-solving). Therefore, the primary outcomes should include at least one of the above indicators. Additionally, given the focus of many exercise intervention studies on academic performance (AP) in obese adolescents, a secondary outcome includes AP. This meta-analysis synthesizes findings from 20 RCTs published between 2010 and 2023, encompassing a total of 1183 overweight or obese participants. Interventions were categorized into seven types: control training (CT), aerobic exercise (AE), resistance training (RT), coordinated physical activity (CPA), prolonged time of exercise (PTE), high-intensity interval training (HIIT), and AE combined with RT (mix mode, MIX). The surface under the cumulative ranking curve (SUCRA) results demonstrated the preferable effects of various interventions on EF improvement. SUCRA values indicate that CPA performs best in improving the accuracy and reaction speed of CF, as well as the reaction speed of inhibitory control in children and adolescents. AE shows significant effects in enhancing AP in this population. Additionally, PTE excels in improving CF and inhibitory control in middle-aged and older adults. Through subgroup analysis based on age and intervention duration, we found AE exhibited a significant effect on interventions for the 0-17 age group (SMD = 0.84, 95%CI = 0.31~1.38, p = 0.002) and interventions lasting 8-16 weeks showed significant improvement in EFs (SMD = 0.53, 95%CI = 0.00~1.05, p = 0.048). There was also a significant difference between CPA intervention and CT (SMD = 1.12, 95%CI = 0.45~1.80, p = 0.001) in children and adolescents. Additionally, PTE showed significant effects for middle-aged adults aged 17-59 (SMD = 0.93, 95%CI = 0.11~1.96, p &lt; 0.027). **Conclusions** : This NMA found that CPA and AE have significant benefits for CF, inhibitory control, and AP in children and adolescents. Furthermore, PTE improves EFs in adults and older adults. Combining the findings of this study with previous related research, we recommend that OW/OB begin by interrupting prolonged sedentary behavior and increasing fragmented physical activity, gradually incorporating AE, RT, and CPA (such as jump rope).
AN  - 39767367
AU  - Guo,
AU  - J.
AU  - Liu,
AU  - J.
AU  - Zhu,
AU  - R.
AU  - Liu,
AU  - G.
AU  - Zheng,
AU  - M.
AU  - Cao,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3390/bs14121227
L1  - internal-pdf://1167981785/Guo-2024-The Impact of Different Types of Exer.pdf
PY  - 2024
SP  - 19
T2  - Behavioral Sciences
TI  - The Impact of Different Types of Exercise on Executive Functions in Overweight/Obese Individuals: A Systematic Review and Network Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3390%2fbs14121227
UR  - https://mdpi-res.com/d_attachment/behavsci/behavsci-14-01227/article_deploy/behavsci-14-01227.pdf?version=1734612189
VL  - 14
ER  -
TY  - JOUR
AB  - **Objective**: To investigate the effects of exercise on executive function in children, providing an evidence-based foundation to inform future research in school physical education and health education. 

**Methods**: We searched ten databases: Cochrane Library, Scopus, OVID, Web of Science, PubMed, EBSCOhost, SPORTDiscus, PsycINFO, CNKI, WANFANG DATA, VIP, and SinoMed, and eight articles were included. Applying the revised Cochrane Risk of Bias Tool for Randomized Trials (RoB2), funnel plots and Egger regression analysis were integrated with R meta-analysis to screen for publication bias. The quality of the evidence was appraised using the Grading system. 

**Results**: The included literature contained 2655 participants, with 1308 in the experimental group and 1347 in the control group. The results indicated that the aerobic exercise group considerably improved inhibitory control in children compared to the control group [SMD = 0.29, 95% CI (0.05, 0.54), P = 0.018]; working memory [SMD = 0.25, 95% CI (0.07, 0.42), P = 0.005]; and cognitive flexibility [SMD = 0.36, 95% CI (0.17, 0.54), P &lt; 0.001]. However, the findings indicated that only aerobic exercise interventions extending beyond 50 weeks positively influenced academic performance in children [SMD = 1.19, 95% CI (0.34, 2.04), P = 0.006]. The results of an Egger regression analysis revealed that the p-values for inhibitory control, working memory, cognitive flexibility, and academic performance were more significant than 0.1. The Grade system said that the quality of evidence was all low regarding the level of evidence. 

**Conclusion**: Aerobic exercise enhanced executive function but only aerobic exercise interventions extending beyond 50 weeks demonstrated a significant effect on the academic performance of children. Due to the low quality of evidence presented in this study, additional high-quality randomized controlled trials are needed to confirm these findings.
AN  - 38586404
AU  - Zang,
AU  - W.
AU  - Zhu,
AU  - J.
AU  - Xiao,
AU  - N.
AU  - Fang,
AU  - M.
AU  - Li,
AU  - D.
AU  - Li,
AU  - H.
AU  - Yan,
AU  - J.
AU  - Jing,
AU  - H.
AU  - Wang,
AU  - S.
DB  - April 24.enl
DO  - /10.1016/j.heliyon.2024.e28633
L1  - internal-pdf://1800743233/Zang-2024-Effects of aerobic exercise on child.pdf
PY  - 2024
SP  - e28633
T2  - Heliyon
TI  - Effects of aerobic exercise on children&#039;s executive function and academic performance: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.1016%2fj.heliyon.2024.e28633
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10998207/pdf/main.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - Previous reviews of online self-help have not exclusively focussed on universally delivered Acceptance and Commitment Therapy (ACT). This systematic review aimed to evaluate the effectiveness of universal online self-help ACT interventions for young people. Relevant databases were searched for studies examining ACT interventions that were delivered universally, online and as self-help (guided and unguided) to young people aged 10 to 25-years-old. Eleven studies met inclusion criteria. These were assessed for quality and findings summarised using a narrative synthesis. Outcomes on mental health, well-being and ACT processes were reviewed, and results across studies were mixed. Most studies found significant improvements in mental health and well-being outcomes following the ACT intervention; however less than half found improvements in ACT process measures. Subgroups, such as those with elevated mental health symptoms, had better outcomes. There were no changes in measures of psychological inflexibility. However, methodological issues limited the interpretation of findings. Heterogeneity between studies and methodological issues made it difficult for this review to draw conclusions regarding the effectiveness of universal online self-help ACT interventions for young people. Future research with consistent approaches is needed across these types of interventions to improve methodological rigour to determine whether these interventions are effective.
AN  - 38852229
AU  - Morey,
AU  - A.
AU  - Samuel,
AU  - V.
AU  - Williams,
AU  - M.
DB  - Juni 24.enl
DO  - /10.1016/j.brat.2024.104576
L1  - internal-pdf://3565382672/1-s2.0-S0005796724001037-main.cleaned.pdf
PY  - 2024
SP  - 104576
T2  - Behaviour Research &amp; Therapy
TI  - Universal online self-help ACT interventions for youth: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.brat.2024.104576
VL  - 180
ER  -
TY  - JOUR
AB  - **Background**
Attention Deficit/Hyperactivity Disorder (ADHD) demonstrates unique developmental manifestations in adolescence with implications for optimized, age-appropriate treatment. This 10-year update is the third in a series of systematic reviews examining the efficacy and safety of adolescent ADHD treatments. We broadly examined efficacy on ADHD symptoms, impairments, and other reported outcomes. Acute and long-term efficacy, and treatment moderators, were considered.

**Method**
We performed PubMed, EMBASE, and PsycINFO searches for articles published or in press from 2013 to 2024, integrated with hand search and randomized controlled trials (RCTs) identified in this series&#039; earlier reviews. RCTs examining the safety or efficacy of interventions delivered to adolescents (ages 10.0-19.9) with a diagnosis of ADHD were included. Study characteristics were extracted and reviewed, quality of evidence was assessed using GRADE, and effect sizes were calculated for individual studies and illustrated using forest plots.

**Results**
Sixty-three RCTs were identified. Quality of evidence ranged from high (medication; k = 29) to very low (nutrient supplementation, neurofeedback, occupational therapy; k = 1 each). Medications demonstrated consistent strong impact on ADHD symptoms and inconsistent impact on impairment. Diverse cognitive/behavioral treatments (C/BTs) demonstrated inconsistent impact on ADHD symptoms but strong and consistent impact on impairment and executive function skills, plus moderate benefits on internalizing symptoms. No interventions demonstrated significant safety concerns. Long-term maintenance (up to 3 years post-treatment) was demonstrated for C/BTs, though moderate quality of evidence was noted because participants cannot be fully blinded to receipt of treatment.

**Conclusions**
The effects of C/BTs and medication appear complementary, not duplicative. Combining medication and C/BT is advised at treatment outset to maximize engagement, maintenance, and response breadth (i.e. improving both ADHD symptoms/cognitive performance and coping skills/functional impairments). Engagement strategies (e.g. motivational interviewing) may facilitate uptake. Novel treatments do not yet demonstrate effects on ADHD symptoms or impairments in adolescents but remain a promising area for research.
AN  - WOS:001326580300001
AU  - Sibley,
AU  - M.
AU  - H.
AU  - Flores,
AU  - S.
AU  - Murphy,
AU  - M.
AU  - Basu,
AU  - H.
AU  - Stein,
AU  - M.
AU  - A.
AU  - Evans,
AU  - S.
AU  - W.
AU  - Zhao,
AU  - X.
AU  - Manzano,
AU  - M.
AU  - van
AU  - Dreel,
AU  - S.
DB  - November 2024.enl
DO  - 10.1111/jcpp.14056
L1  - internal-pdf://1038975413/Sibley-2024-Research Review_ Pharmacological a.pdf
PY  - 2024
SP  - 18
T2  - Journal of Child Psychology and Psychiatry
TI  - Research Review: Pharmacological and non-pharmacological treatments for adolescents with attention deficit/hyperactivity disorder - a systematic review of the literature
UR  - &lt;Go to ISI&gt;://WOS:001326580300001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.14056?download=true
ER  -
TY  - JOUR
AB  - **Background**
Cognitive behavioural therapy (CBT) can be effective in people with schizophrenia when provided in combination with antipsychotic medication. It remains unclear whether CBT could be safely and effectively offered in the absence of concomitant antipsychotic therapy.

**Objectives**
To investigate the effects of CBT for schizophrenia when administered without concomitant pharmacological treatment with antipsychotics.

**Search methods**
We conducted a systematic search on 6 March 2022 in the Cochrane Schizophrenia Group&#039;s Study‐Based Register of Trials, which is based on CENTRAL, MEDLINE, Embase, CINAHL, PsycINFO, PubMed, ClinicalTrials.gov, and WHO ICTRP.

**Selection criteria**
We included randomised controlled trials (RCTs) in people with schizophrenia comparing CBT without antipsychotics to standard care, standard care without antipsychotics, or the combination of CBT and antipsychotics.

**Data collection and analysis**
Two review authors independently screened references for inclusion, extracted data from eligible studies, and assessed risk of bias using Cochrane&#039;s RoB 2 tool. We contacted study authors for missing data and additional information. Our primary outcome was general mental state measured with a validated rating scale. Key secondary outcomes were specific symptoms of schizophrenia, relapse, service use, number of participants leaving the study early, functioning, quality of life, and number of participants actually receiving antipsychotics during the trial. We also assessed behaviour, adverse effects, and mortality.

**Main results**
We included 4 studies providing data for 300 participants (average age 21.94 years). The mean sample size was 75 participants (range 61 to 90 participants). Study duration was between 26 and 39 weeks for the intervention period and 26 to 104 weeks for the follow‐up period. Three studies employed a blind rater, while one study was triple‐blind.

All analyses included data from a maximum of three studies. The certainty of the evidence was low or very low for all outcomes.

For the primary outcome overall symptoms of schizophrenia, results showed a difference favouring CBT without antipsychotics when compared to no specific treatment at long term (&gt; 1 year mean difference measured with the Positive and Negative Syndrome Scale (PANSS MD) &minus;14.77, 95% confidence interval (CI) &minus;27.75 to &minus;1.79, 1 RCT, n = 34). There was no difference between CBT without antipsychotics compared with antipsychotics (up to 12 months PANSS MD 3.38, 95% CI &minus;2.38 to 9.14, 2 RCTs, n = 63) (very low‐certainty evidence) or compared with CBT in combination with antipsychotics (up to 12 months standardised mean difference (SMD) 0.30, 95% CI &minus;0.06 to 0.65, 3 RCTs, n = 125).

Compared with no specific treatment, CBT without antipsychotics was associated with a reduction in overall symptoms (as described above) and negative symptoms (PANSS negative MD &minus;4.06, 95% CI &minus;7.50 to &minus;0.62, 1 RCT, n = 34) at longer than 12 months. It was also associated with a lower duration of hospital stay (number of days in hospital MD &minus;22.45, 95% CI &minus;28.82 to &minus;16.08, 1 RCT, n = 74) and better functioning (Personal and Social Performance Scale MD &minus;12.42, 95% CI &minus;22.75 to &minus;2.09, 1 RCT, n = 40, low‐certainty evidence) at up to 12 months.

We did not find a difference between CBT and antipsychotics in any of the investigated outcomes, with the exception of adverse events measured with the Antipsychotic Non‐Neurological Side‐Effects Rating Scale (ANNSERS) at both 6 and 12 months (MD &minus;4.94, 95% CI &minus;8.60 to &minus;1.28, 2 RCTs, n = 48; MD &minus;6.96, 95% CI &minus;11.55 to &minus;2.37, 2 RCTs, n = 42).

CBT without antipsychotics was less effective than CBT combined with antipsychotics in reducing positive symptoms at up to 12 months (SMD 0.40, 95% CI 0.05 to 0.76, 3 RCTs, n = 126). CBT without antipsychotics was associated with a lower number of participants experiencing at least one adverse event in comparison with CBT combined with antipsychotics at up to 12 months (risk ratio 0.36, 95% CI 0.17 to 0.80, 1 RCT, n = 39, low‐certainty evidence).

**Authors&#039; conclusions**
This review is the first attempt to systematically synthesise the evidence about CBT delivered without medication to people with schizophrenia. The limited number of studies and low to very low certainty of the evidence prevented any strong conclusions. An important limitation in the available studies was that participants in the CBT without medication group (about 35% on average) received antipsychotic treatment, highlighting the challenges of this approach. Further high‐quality RCTs are needed to provide additional data on the feasibility and efficacy of CBT without antipsychotics.
AN  - CD015332
AU  - Bighelli,
AU  - I.
AU  - &Ccedil;ıray,
AU  - O.
AU  - Salahuddin,
AU  - N.
AU  - H.
AU  - Leucht,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/14651858.CD015332.pub2
KW  - *Antipsychotic Agents [therapeutic use]
KW  - *Cognitive Behavioral Therapy [methods]
KW  - *Schizophrenia [drug therapy]
KW  - Adult
KW  - Humans
KW  - Neoplasm Recurrence, Local [drug therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Young Adult
L1  - internal-pdf://0092274377/Bighelli_sup_a__sup__et_al-2024-Cochrane_Datab.pdf
N1  - [Schizophrenia]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive behavioural therapy without medication for schizophrenia
UR  - http://dx.doi.org/10.1002/14651858.CD015332.pub2
ER  -
TY  - JOUR
AB  - **Background**
Sleep disturbances are common for children with autism spectrum disorder (ASD) and can have detrimental effects. Sleep disturbances may negatively impact the general well-being and quality of life of children.

**Objectives**
The purpose of this systematic review was to examine the effect of physical activity (PA) interventions and massage therapy (MT) on sleep disturbances in children with ASD.

**Methods**
We reviewed empirical research focusing on the effect of PA and MT on sleep-related variables published from inception to January 2023. Five electronic databases (PubMed, MEDLINE, Google Scholar, PsycInfo, and Web of Science) were included in the search. Outcomes included sleep efficiency, sleep-onset latency, sleep duration, sleep behavior, and sleep quality. PEDro and McMaster&#039;s scales were used to assess the quality of included studies.

**Results**
The search yielded a total of 20 studies meeting all inclusion criteria. Fifteen studies related to the effects of PA and five studies related to the effects of MT on sleep disorders in children with ASD. The total number of participants was 511.

**Conclusion**
PA and MT have beneficial effects on sleep efficiency, sleep-onset latency, wake after sleep onset, and sleep quality. In addition, aquatic exercise and swimming were found to be particularly effective in improving sleep in children with ASD.
AN  - WOS:001157445700001
AU  - Ekradi,
AU  - S.
AU  - Shahrbanian,
AU  - S.
AU  - Todd,
AU  - T.
AU  - Hassani,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1007/s40489-024-00433-6
L1  - internal-pdf://3917618087/Ekradi-2024-Effects of Physical Activity and M.pdf
PY  - 2024
SP  - 17
T2  - Review Journal Of Autism And Developmental Disorders
TI  - Effects of Physical Activity and Massage Therapy on Sleep Disorders Among Children with Autism Spectrum Disorder: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001157445700001
UR  - https://link.springer.com/article/10.1007/s40489-024-00433-6
UR  - https://link.springer.com/content/pdf/10.1007/s40489-024-00433-6.pdf
ER  -
TY  - JOUR
AB  - Many youth experience mental health problems and digital games hold potential as mental health interventions. This systematic review provides an overview of randomised controlled studies assessing the effectiveness of digital applied and casual games for improving mental health in youth aged 6-24 years. A systematic search of PsycINFO, Web of Science and Pubmed yielded 145 eligible studies. Studies on (sub)clinical participant samples (n = 75) most often focused on attention-deficit/hyperactivity disorder (ADHD), autism and anxiety. Applied games were found most effective for improving social skills, verbal memory and anxiety, whereas casual games were found most effective for improving depression, anxiety and ADHD. Studies involving healthy youth (n = 70) were grouped into papers examining anxiety in medical settings, momentary effects on positive and negative affect, and papers employing a longitudinal design measuring mental health trait outcomes. Promising results were found for the use of games as distraction tools in medical settings, and for applied and casual games for improving momentary affect. Overall, our findings demonstrate the potential of digital games for improving mental health. Implications and recommendations for future research are discussed, such as developing evaluation guidelines, clearly defining applied games, harmonising outcome measures, including positive outcomes, and examining nonspecific factors that may influence symptom improvement as well.
AN  - 38320420
AU  - Wols,
AU  - A.
AU  - Pingel,
AU  - M.
AU  - Lichtwarck-Aschoff,
AU  - A.
AU  - Granic,
AU  - I.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.cpr.2024.102396
L1  - internal-pdf://2269669253/1-s2.0-S0272735824000175-main.cleaned.pdf
PY  - 2024
SP  - 102396
T2  - Clinical Psychology Review
TI  - Effectiveness of applied and casual games for young people&#039;s mental health: A systematic review of randomised controlled studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=38320420
UR  - https://www.sciencedirect.com/science/article/pii/S0272735824000175?via%3Dihub
VL  - 108
ER  -
TY  - JOUR
AB  - Preoperative anxiety (POA) is a concern for children undergoing surgery, especially with general anesthesia. POA can result in many postoperative problems, such as physical, psychological, and financial problems. Nonpharmacological treatments have been investigated for reducing POA as they are more pleasant and have fewer adverse effects compared to pharmacological treatments. Audiovisual technology treatment is one of the nonpharmacological treatments developed lately. This study aims to evaluate the efficacy of an audiovisual technology intervention for reducing POA in children undergoing general anesthesia. This study was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guideline 2020. Google Scholar, PubMed, ProQuest, and Cochrane databases were used for searching English articles published between January 2015 and June 2023. Cochrane Review Manager 5.4 was used for the meta-analysis and the Risk of Bias Tool 2.0 was used to measure the risk of bias. The studies included were randomized controlled trials (RCTs) that compared the audiovisual technology intervention with a control population. The modified Yale Preoperative Anxiety Scale was the outcome of interest. We found 627 articles in four databases using the search term. After screening with the eligibility criteria, three studies from Iran, Denmark, and China were included in the meta-analysis. A random effect model was applied. The meta-analysis resulted in a significant result as a lower modified Yale Preoperative Anxiety Scale score was found in the audiovisual technology intervention group compared with the control group (mean difference -10.75 [-16.48 to -5.03]; 95% confidence interval; P = .0002.) The presence of audiovisual technology interventions such as video games, cartoons or animation videos, and smartphone applications could significantly lower POA in children undergoing general anesthesia.
AN  - WOS:001266553300001
AU  - Oktaviani,
AU  - J.
AU  - R.
AU  - Widjaja,
AU  - V.
AU  - Singgih,
AU  - N.
AU  - A.
AU  - Secodiningrat,
AU  - Rhps
DB  - August 2024.enl
DO  - 10.4103/jehp.jehp_1344_23
L1  - internal-pdf://2639553358/audiovisual_technology_intervention_for_reduci.pdf
PY  - 2024
SP  - 7
T2  - Journal of Education and Health Promotion
TI  - Audiovisual technology intervention for reducing preoperative anxiety in children undergoing general anesthesia: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001266553300001
VL  - 13
ER  -
TY  - JOUR
AB  - PROBLEM: Virtual reality (VR) is used as a novel intervention technique to alleviate uncomfortable experiences such as anxiety and pain in children. Recently, VR distraction has gained prominence in pediatric medical procedures. However, no studies have yet conducted a further quantitative analysis of the intervention effects of virtual reality exposure (VRE). This systematic review aims to analyse the effect of VRE on anxiety and pain levels in paediatric patients undergoing medical procedures. 

ELIGIBILITY CRITERIA</b>: Relevant studies were searched from four databases, including PubMed, Cochrane Library, Embase, and Web of Science. This systematic review has been registered in the International Prospective Register of Systematic Reviews (PROSPERO). 

RESULTS: The meta-analysis incorporated a total of 11 articles, encompassing 1,099 pediatric patients. The results showed that VRE relieved children&#039;s anxiety [SMD = -0.61, 95% CI (-0.93, -0.28), p &lt; 0.001], but there was no significant difference in alleviating pain in children [SMD = -1.48, 95% CI (-3.40, 0.44), p = 0.131]. 

CONCLUSIONS: The results suggest that VRE is effective in reducing children&#039;s anxiety during medical procedures. However, 7 of the 11 original studies included in this review were from the same research project, which may increase the risk of reporting bias. Also, more high-quality studies are needed in the future to verify its effectiveness for pain levels. 

IMPLICATIONS: VRE can help children become familiar with the medical environment, overcome anxiety and fear, and learn about medical procedures in advance. This can enhance their cooperation during medical process, leading to a more positive medical experience.
AN  - 39085008
AU  - Hu,
AU  - Z.
AU  - Yao,
AU  - J.
AU  - He,
AU  - L.
AU  - Li,
AU  - X.
AU  - Guo,
AU  - Y.
DB  - August 2024.enl
DO  - /10.1016/j.pedn.2024.07.027
L1  - internal-pdf://2627230653/1-s2.0-S0882596324002896-main.pdf
PY  - 2024
SP  - 30
T2  - Journal of Pediatric Nursing
TI  - The impact of virtual reality exposure on anxiety and pain levels in pediatric patients: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.pedn.2024.07.027
VL  - 30
ER  -
TY  - JOUR
AB  - Objective: Overweight and obesity are serious public health issues worldwide and significantly impair children&#039;s executive function (EF). However, there is no consensus regarding the benefits of aerobic exercise, on the EF of overweight and obese children. This study systematically evaluated the intervention effects of aerobic exercise on EF and its subcomponents (inhibitory control, working memory, and cognitive flexibility) in overweight and obese children. 

Methods: We searched six databases-PubMed, Web of Science, Cochrane Library, Embase, EBSCOhost, and China National Knowledge Infrastructure-until March 17, 2024 for randomized controlled trials examining the effects of aerobic exercise on the EF of overweight and obese children the Cochrane Risk of Bias Assessment Tool. Following heterogeneity testing, RevMan 5.4 and Stata 17.0 were used for meta-analysis and subgroup analysis of the three indicators. The standardized mean difference (SMD) and 95% confidence intervals (CI) were used as statistical measures for effect analysis with the SMD value as the effect size and a p-value of &lt;=0.05 indicating statistical significance. 

Results: Eighteen studies involving 1,260 participants were included. Aerobic exercise significantly improved overall EF (SMD = -0.50, 95% CI [-0.68, -0.32], p &lt; 0.01) with a moderate to high positive effect on inhibitory control (SMD = -0.52, 95% CI [-0.72, -0.31], p &lt; 0.01) and working memory (SMD = -0.63, 95% CI [-1.06, -0.20], p &lt; 0.01) but not on cognitive flexibility (SMD = -0.32, 95% CI [-0.71, 0.07], p = 0.11). These results suggest that EF in overweight and obese children is influenced by factors such as exercise characteristics and body mass index (BMI). Subgroup analysis revealed a significant moderating effect of exercise type, exercise intensity, session time, and individual BMI on EF. 

Conclusion: Aerobic exercise selectively improved EF in overweight and obese children. Subgroup analysis indicated that cognitive engagement in ball game interventions of at least moderate intensity and a single session of 25-40 min are more beneficial for improving EF in overweight and obese children. Extremely obese children (BMI &gt; 25 kg/m&lt;sup&gt;2&lt;/sup&gt;) do not benefit from the intervention, highlighting the need for a specific focus on intervention outcomes in future studies.
AN  - 39529725
AU  - Wang,
AU  - Y.
AU  - Wang,
AU  - H.
AU  - Zhao,
AU  - H.
DB  - November 2024.enl
DO  - /10.3389/fpsyg.2024.1485610
L1  - internal-pdf://3553130372/Wang-2024-Effects of aerobic exercise on execu.pdf
PY  - 2024
SP  - 1485610
T2  - Frontiers in Psychology
TI  - Effects of aerobic exercise on executive function among overweight and obese children: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffpsyg.2024.1485610
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11551034/pdf/fpsyg-15-1485610.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Research on attention towards non-social stimuli in preschoolers with autism spectrum disorder (ASD) has increased over the past decade; however, findings have been inconsistent. It has been suggested that stimuli relating to common circumscribed interests (CIs) elicit more attention than non-CI related stimuli. This meta-analysis synthesizes results from 31 studies that compared attention towards non-social stimuli in children with ASD under the age of five with typically developing (TD) controls using eye-tracking. Additional subgroup analysis comparing studies that employed non-social stimuli related to CIs frequently reported in adults with ASD to studies using non-CI related stimuli were conducted. Meta-regressions with age, sex, stimulus dimension, nonverbal DQ, and symptom severity were conducted. Results show small (g = 0.39) but significantly higher attention towards non-social stimuli for the ASD group. However, when studies were split based on stimulus type no significant differences for non-CI related stimuli was found. Meanwhile studies employing CI related stimuli reported significant large effects on attention allocation (g = 0.69). None of the conducted regressions reached significance. The findings show increased non-social attention in children with ASD is driven by CI related content rather than a general non-social attentional bias. The findings and future research directions are discussed.
AN  - 39503176
AU  - Hinz,
AU  - J.
AU  - R.
AU  - Eikeseth,
AU  - F.
AU  - F.
AU  - Chawarska,
AU  - K.
AU  - Eikeseth,
AU  - S.
DB  - November 2024.enl
DO  - /10.1002/aur.3261
L1  - internal-pdf://3720380978/Hinz-2024-A systematic review and meta-analysi.pdf
PY  - 2024
SP  - 06
T2  - Autism research : Official Journal of the International Society for Autism Research
TI  - A systematic review and meta-analysis of atypical visual attention towards non-social stimuli in preschoolers with autism spectrum disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1002%2faur.3261
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aur.3261?download=true
VL  - 06
ER  -
TY  - JOUR
AB  - **Introduction** 
Recently, studies on behavioral tic suppression techniques have gained popularity as opposed to pharmacological alternatives that often have potentially dangerous side effects. Differential Reinforcement of Other Behaviors therapy (DRO) is one such behavioral technique whose efficacy in tic suppression has been experimentally demonstrated albeit in studies with very few patients, and lacking statistical power. Here, we conducted a meta-analysis of these studies to improve their overall power and explore whether DRO intervention is really effective for tic suppression.

**Materials and methods** 
PubMed, Embase, PsycINFO, and Cochrane Library were searched from inception to August 30, 2023. Only original interventional studies that examined the efficacy of DRO for tic suppression were included.

**Results**
A total of 8 no control interventional studies involving 79 children with tic disorders were recruited. Most of the children had moderate tic severity. The pooled mean Yale Global Tic Severity Scale (YGTSS) score was 24.64 (95% CI: 21.99 - 30.12, p = &lt; 0.00001, I-2 = 87%). In terms of efficacy of the DRO technique for tic suppression, the results showed that DRO was effective in reducing tic frequency among the children. The pooled standardized mean difference (SMD) was -10.25 (95% CI: -14.71 - -5.79, p = &lt; 0.00001) with I-2 = 94%.

**Conclusion** 
In conclusion, this study revealed that DRO is potentially an effective tic suppression technique for temporarily managing tic disorder. It also showed that DRO could be employed for both moderate and severe tic disorders. However, the technique bears crucial limitations that limit its implementation outside of experimental settings. More studies are needed to address these limitations and improve its applicability in the real world.
AN  - WOS:001135383000004
AU  - Mohamed,
AU  - Z.
AU  - A.
AU  - Xue,
AU  - Y.
AU  - Bai,
AU  - M.
AU  - S.
AU  - Dong,
AU  - H.
AU  - Y.
AU  - Jia,
AU  - F.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1186/s12883-023-03501-2
L1  - internal-pdf://1269269637/Mohamed-2024-Efficacy of differential reinforc.pdf
PY  - 2024
SP  - 8
T2  - Bmc Neurology
TI  - Efficacy of differential reinforcement of other behaviors therapy for tic disorder: a meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001135383000004
UR  - https://bmcneurol.biomedcentral.com/counter/pdf/10.1186/s12883-023-03501-2.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - **Background**
Vitamin B12 deficiency is a major public health problem worldwide, with the highest burden in elderly people, pregnant women, and young children. Due to its role in DNA synthesis and methylation, folate metabolism, and erythropoiesis, vitamin B12 supplementation during pregnancy may confer longer‐term benefits to maternal and child health outcomes.

**Objectives**
To evaluate the benefits and harms of oral vitamin B12 supplementation during pregnancy on maternal and child health outcomes.

**Search methods**
We searched the Cochrane Pregnancy and Childbirth&#039;s Trials Register, ClinicalTrials.gov, the World Health Organization International Clinical Trials Registry Platform (ICTRP) on 2 June 2023, and reference lists of retrieved studies.

**Selection criteria**
Randomised controlled trials (RCTs), quasi‐RCTs, or cluster‐RCTs evaluating the effects of oral vitamin B12 supplementation compared to placebo or no vitamin B12 supplementation during pregnancy.

**Data collection and analysis**
We used standard Cochrane methods. Four review authors independently assessed trial eligibility. Two review authors independently extracted data from included studies and conducted checks for accuracy. Three review authors independently assessed the risk of bias of the included studies using the Cochrane RoB 1 tool. We used GRADE to evaluate the certainty of evidence for primary outcomes.

**Main results**
The review included five trials with 984 pregnant women. All trials were conducted in low‐ and middle‐income countries, including India, Bangladesh, South Africa, and Croatia. At enrolment, 26% to 51% of pregnant women had vitamin B12 deficiency (less than 150 pmol/L), and the prevalence of anaemia (haemoglobin less than 11.0 g/dL) ranged from 30% to 46%. The dosage of vitamin B12 supplementation varied from 5 &mu;g/day to 250 &mu;g/day, with administration beginning at 8 to 28 weeks&#039; gestation through to delivery or three months&#039; postpartum, and the duration of supplementation ranged from 8 to 16 weeks to 32 to 38 weeks. Three trials, involving 609 pregnant women, contributed data for meta‐analyses of the effects of vitamin B12 supplementation compared to placebo or no vitamin B12 supplementation.

Maternal anaemia: there may be little to no difference for maternal anaemia by intervention group, but the evidence is very uncertain (70.9% versus 65.0%; risk ratio (RR) 1.08, 95% confidence interval (CI) 0.93 to 1.26; 2 trials, 284 women; very low‐certainty evidence).

Maternal vitamin B12 status: vitamin B12 supplementation during pregnancy may reduce the risk of maternal vitamin B12 deficiency compared to placebo or no vitamin B12 supplementation, but the evidence is very uncertain (25.9% versus 67.9%; RR 0.38, 95% CI 0.28 to 0.51; 2 trials, 272 women; very low‐certainty evidence). Women who received vitamin B12 supplements during pregnancy may have higher total vitamin B12 concentrations compared to placebo or no vitamin B12 supplementation (mean difference (MD) 60.89 pmol/L, 95% CI 40.86 to 80.92; 3 trials, 412 women). However, there was substantial heterogeneity (I2 = 85%).

Adverse pregnancy outcomes: the evidence is uncertain about the effect on adverse pregnancy outcomes, including preterm birth (RR 0.97, 95% CI 0.55 to 1.74; 2 trials, 340 women; low‐certainty evidence), and low birthweight (RR 1.50, 95% CI 0.93 to 2.43; 2 trials, 344 women; low‐certainty evidence). Two trials reported data on spontaneous abortion (or miscarriage); however, the trials did not report quantitative data for meta‐analysis and there was no clear definition of spontaneous abortion in the study reports. No trials evaluated the effects of vitamin B12 supplementation during pregnancy on neural tube defects.

Infant vitamin B12 status: children born to women who received vitamin B12 supplementation had higher total vitamin B12 concentrations compared to placebo or no vitamin B12 supplementation (MD 71.89 pmol/L, 95% CI 20.23 to 123.54; 2 trials, 144 children).

Child cognitive outcomes: three ancillary analyses of one trial reported child cognitive outcomes; however, data were not reported in a format that could be included in quantitative meta‐analyses. In one study, maternal vitamin B12 supplementation did not improve neurodevelopment status (e.g. cognitive, language (receptive and expressive), motor (fine and gross), social‐emotional, or adaptive (conceptual, social, practical) domains) in children compared to placebo (9 months, Bayley Scales of Infant and Toddler Development Third Edition (BSID‐III); 1 trial; low‐certainty evidence) or neurophysiological outcomes (72 months, event‐related potential measures; 1 trial; low‐certainty evidence), though children born to women who received vitamin B12 supplementation had improved expressive language domain compared to placebo (30 months, BSID‐III; 1 trial; low‐certainty evidence).

**Authors&#039; conclusions**
Oral vitamin B12 supplementation during pregnancy may reduce the risk of maternal vitamin B12 deficiency and may improve maternal vitamin B12 concentrations during pregnancy or postpartum compared to placebo or no vitamin B12 supplementation, but the evidence is very uncertain. The effects of vitamin B12 supplementation on other primary outcomes assessed in this review were not reported, or were not reported in a format for inclusion in quantitative analyses. Vitamin B12 supplementation during pregnancy may improve maternal and infant vitamin B12 status, but the potential impact on longer‐term clinical and functional maternal and child health outcomes has not yet been established.
AN  - CD013823
AU  - Finkelstein,
AU  - J.
AU  - L.
AU  - Fothergill,
AU  - A.
AU  - Venkatramanan,
AU  - S.
AU  - Layden,
AU  - A.
AU  - J.
AU  - Williams,
AU  - J.
AU  - L.
AU  - Crider,
AU  - K.
AU  - S.
AU  - Qi,
AU  - Y.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/14651858.CD013823.pub2
KW  - *Abortion, Spontaneous
KW  - *Anemia
KW  - Child
KW  - Child, Preschool
KW  - Dietary Supplements
KW  - Female
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - Outcome Assessment, Health Care
KW  - Pregnancy
KW  - Vitamin B 12
KW  - Vitamins
L1  - internal-pdf://0030287305/Finkelstein_et_al-2024-Cochrane_Database_of_Sy.pdf
N1  - [Pregnancy and Childbirth]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
UR  - http://dx.doi.org/10.1002/14651858.CD013823.pub2
ER  -
TY  - JOUR
AB  - OBJECTIVE: This study aimed to evaluate the acceptability and effects of internet-based cognitive behavioral therapy (iCBT) or CBT-oriented interventions compared with control groups on depressive symptoms, remission of depression, and quality of life (QOL) in adolescents. 

METHODS: We searched English and Chinese databases for randomized controlled trials up to October 10, 2024 that investigated the effects of iCBT compared with controls in adolescents exhibiting elevated depressive symptoms or diagnosed with depression. Standardized mean differences (SMDs), relative risks (RRs), and 95% confidence intervals were applied to evaluate the pooled effects of outcomes. 

RESULTS: A total of 19 RCTs involving 3574 cases were included in this study. We found small effects on depressive symptoms severity at different time points (posttest: SMD = -0.49 [-0.66, -0.33]; 3-month follow-up [FU3]: SMD = -0.21 [-0.30, -0.11]; FU6: SMD = -0.18 [-0.35, -0.02]; FU12: SMD = -0.38 [-0.56, -0.20]). We also found a significant effect in depression remission rate at the posttest (RR = 1.74 [1.36, 2.21]) and a significant effect in QOL at the posttest (SMD = 0.30 [0.07, 0.54]). However, the result regarding acceptability was nonsignificant (RR = 1.22 [0.76, 1.97]). No significant publication bias was found in these results. 

CONCLUSION: iCBT or internet-based CBT-oriented interventions can effectively reduce depressive symptom severity and improve depression remission rate and QOL in depressed adolescents. These results are preliminary and require further validation through future systematic reviews.
AN  - 39582126
AU  - Liu,
AU  - P.
AU  - Situ,
AU  - M.
AU  - Duan,
AU  - X.
AU  - Sun,
AU  - H.
AU  - Wang,
AU  - M.
AU  - Tao,
AU  - Y.
AU  - Luo,
AU  - T.
AU  - Li,
AU  - S.
AU  - Wang,
AU  - Z.
AU  - Huang,
AU  - Y.
DB  - November 2024.enl
DO  - /10.1111/jebm.12657
L1  - internal-pdf://2142275208/Liu-2024-The Acceptability and Effects of Inte.pdf
PY  - 2024
SP  - 24
T2  - Journal of Evidence based Medicine
TI  - The Acceptability and Effects of Internet-Based Cognitive Behavioral Therapy on Depressive Symptoms and Remission in 13- to 17-Year-Old Adolescents: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1111%2fjebm.12657
UR  - https://onlinelibrary.wiley.com/doi/10.1111/jebm.12657
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jebm.12657?download=true
VL  - 24
ER  -
TY  - JOUR
AB  - This study aimed to evaluate the effectiveness of Exergaming in improving executive function and motor ability across different groups of children and adolescents. We searched several databases, including PsycINFO, Web of Science, Embase, PubMed, SPORT Discus, Scopus, and the Cochrane Central Register of Controlled Trials, for randomized controlled trial (RCT) studies published from inception until November 25, 2023, to identify studies investigating the effect of Exergaming on motor and executive function in children. The protocol was registered with PROSPERO (CRD42023482281). A total of 37 randomized controlled trials were included in this study. Our results indicate that Exergaming can influence children&#039;s cognitive flexibility [SMD = 0.34, 95%CI(0.13,0.55), I2 = 0.0%, P = 0.738], inhibition control [SMD = 0.51, 95%CI (0.30,0.72), I2 = 0.0%, P = 0.473], global cognitive [SMD = 0.87, 95%CI (0.50,1.23), I2 = 0.0%, P = 0.974], working memory [SMD = 0.18, 95%CI(-0.16, 0.52), I2 = 46.5%, P = 0.096], gross motor skills [SMD = 0.82, 95%CI (0.30, 1.35), I2 = 79.1%, P&lt;0.001], fine motor skills [SMD = 0.71, 95%CI (0.22,1.21), I2 = 78.7%, P&lt;0.001], balance [SMD = 0.61, 95%CI (0.34, 0.88), I2 = 59.5%, P = 0.001], and cardiorespiratory [SMD = 0.48, 95%CI (0.16, 0.79), I2 = 58.4%, P = 0.019]. While these findings suggest that Exergaming can promote children&#039;s cognitive flexibility, inhibitory control, global cognition and motor abilities, the effect on working memory was not statistically significant. Further high-quality randomized controlled trials are warranted to explore the potential benefits of Exergaming for different groups of children, including those with specific needs.
AN  - 39240840
AU  - Kou,
AU  - R.
AU  - Zhang,
AU  - Z.
AU  - Zhu,
AU  - F.
AU  - Tang,
AU  - Y.
AU  - Li,
AU  - Z.
DB  - September 2024.enl
DO  - /10.1371/journal.pone.0309462
L1  - internal-pdf://2118015808/Kou-2024-Effects of Exergaming on executive fu.pdf
PY  - 2024
SP  - e0309462
T2  - PLoS ONE [Electronic Resource]
TI  - Effects of Exergaming on executive function and motor ability in children: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1371%2fjournal.pone.0309462
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0309462&amp;type=printable
VL  - 19
ER  -
TY  - JOUR
AB  - This meta-analysis evaluated the effectiveness of Parent-Child Interaction Therapy (PCIT) for maltreated families and examined potential moderators associated with the intervention. Seven English electronic databases (PubMed, PsycINFO, Web of Science, MEDLINE, Scopus, Cochrane Library, and ProQuest Dissertations and Theses Global) were systematically searched to identify randomized controlled trials (RCTs) published before January 20, 2023. Eleven studies involving 1,069 maltreated or high-risk families were included in the meta-analysis. Our results showed that PCIT significantly reduced child externalizing behaviors, improved parenting skills, and decreased parenting stress and child abuse potential in maltreated families. Additionally, families with confirmed maltreatment history reported larger effect sizes across all outcomes than those at high risk of maltreatment; parenting skills outcomes were more effective in adapted PCIT versions, using per-protocol analysis, and American caregivers, whereas none of the outcomes were related to the number of sessions. These findings provide encouraging evidence for the use of PCIT as an intervention for families with a history of maltreatment, although more high-quality RCTs are required to confirm its effects.
AN  - 38287915
AU  - Zhang,
AU  - H.
AU  - Wang,
AU  - W.
AU  - Li,
AU  - Z.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/15248380231222041
L1  - internal-pdf://0109352145/zhang-et-al-2024-effectiveness-of-parent-child.pdf
PY  - 2024
SP  - 15248380231222041
T2  - Trauma Violence &amp; Abuse
TI  - Effectiveness of Parent-Child Interaction Therapy for Maltreated Families: A Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38287915
UR  - https://journals.sagepub.com/doi/10.1177/15248380231222041
ER  -
TY  - JOUR
AB  - Background
Children in foster care are at high risk of future mental health and developmental difficulties. A number of interventions may be helpful; however, the effectiveness of interventions specifically for pre-school children in foster care is not well established. This is an important omission, since infancy and early childhood may be the optimal period for interventions to prevent future problems. The current systematic review set out to establish the existing evidence base for interventions to improve social-emotional, developmental and relational outcomes for pre-school children in foster and kinship care.

Methods
Searches of online databases were undertaken in June 2023 with keyword search terms related to the study population and design. Studies utilising a randomised control design to measure the effectiveness of interventions for foster children aged 0&ndash;7 years were included. The methodological quality of included studies was assessed using the Cochrane Risk of Bias (ROB-2) tool and effects evaluated using narrative synthesis and GRADE assessments of included interventions and outcomes.

Results
Searches identified 6815 results. Twenty studies, describing seven interventions, met inclusion criteria. Fifteen studies reported intervention benefits comparative to control in at least one outcome domain, with particularly good evidence for Attachment and Behaviour Catch-Up (ABC) in improving developmental outcomes. There was also evidence for Multi-Treatment Foster Care for Pre-Schoolers (MTFC-P), Kids In Transition To School (KITS), Parent-Child Interaction Therapy (PCIT) and HeadStart in improving behavioural outcomes. The findings for relational outcomes, including attachment, were mixed; however, there was some evidence for MTFC-P and ABC in reducing avoidant attachment.

Conclusions
This systematic review contributes to our current understanding of how we might best support pre-school children in foster care. It remains unclear whether the effectiveness of particular interventions may be moderated by participant or intervention characteristics. Further research is needed to understand which interventions work best for whom in this group. Despite some variability in methodological quality and heterogeneity across studies, our findings suggest that certain interventions are likely to be helpful for young children in foster care. Dissemination and ongoing evaluation of the evidence-based interventions highlighted within this review should be implemented in clinical practice.
AN  - 2025-22609-001
AU  - Kirby,
AU  - Natalie
AU  - Biggs,
AU  - Camilla
AU  - Garside,
AU  - Megan
AU  - Cheung,
AU  - Gloria
AU  - Wilson,
AU  - Philip
AU  - Forde,
AU  - Matt
AU  - Deidda,
AU  - Manuela
AU  - Ougrin,
AU  - Dennis
AU  - Turner,
AU  - Fiona
AU  - Crawford,
AU  - Karen
AU  - Minnis,
AU  - Helen
DB  - September 2024.enl
DO  - /10.1002/jcv2.12273
L1  - internal-pdf://3243267600/JCPP Advances - 2024 - Kirby - Interventions f.pdf
PY  - 2024
SP  - No Pagination Specified
T2  - Jcpp Advances
TI  - Interventions for pre-school children in foster care: A systematic review of randomised controlled trials of child-related outcomes
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.1002%2fjcv2.12273
ER  -
TY  - JOUR
AB  - **Background:** 
The administration of omega-3 polyunsaturated fatty acid supplements is recommended as an adjuvant therapy for adults diagnosed with major depressive disorder. The evaluation of replicated data in combination treatment with omega-3 has been extensively conducted in adults over the past decade. However, the generalizability of these findings to pediatric groups is still uncertain. 

The objectives of this evaluation were twofold: (1) to evaluate the effectiveness of omega-3 and associated combination therapies in reducing the severity of depressive symptoms, and (2) to include remission rates (i.e., reduction of more than 50% in depression symptoms) as a measure of therapeutic efficacy.

**Methods:**
 We conducted a literature search on PubMed/EMBASE from inception to October 2023. Data analyses were conducted using Stata (version 17.0).

**Results:** 
We identified a total of 3168 articles. After eligibility screening of identified studies, nine studies (n = 561 participants) were included in our analysis herein. Pairwise comparisons revealed no significant improvement in depression symptoms for any intervention versus placebo. However, a clustered ranking plot identified omega-3 plus inositol as the most effective treatment for pediatric depression (77.3% efficacy). Omega-3 paired with psychoeducational psychotherapy significantly lowered the remission rate compared to placebo (standardized mean difference = 0.44, 95% confidence interval: 0.00-0.87, p = 0.048), resulting in a 91.5% remission rate, making it the most effective treatment in the study.

**Conclusions:** 
Taken together, this network meta-analysis presents compelling evidence supporting the antidepressant effects of omega-3 in pediatric groups with depression. Future research should aim to investigate omega-3 as monotherapy for young individuals with depression, as well as investigate the efficacy of omega-3 in comparison to psychosocial interventions for affected individuals.
AN  - WOS:001260938300001
AU  - Lam,
AU  - C.
AU  - Han,
AU  - L.
AU  - McIntyre,
AU  - R.
AU  - S.
AU  - Teopiz,
AU  - K.
AU  - M.
AU  - Cao,
AU  - B.
DB  - Juli 2024.enl
DO  - 10.1089/cap.2024.0017
L1  - internal-pdf://0989673923/lam-et-al-2024-comparative-efficacy-of-omega-3.pdf
PY  - 2024
SP  - 10
T2  - Journal of Child and Adolescent Psychopharmacology
TI  - Comparative Efficacy of Omega-3 Fatty Acid with Other Interventions for Depression in Children and Adolescents: A Systematic Review and Network Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001260938300001
ER  -
TY  - JOUR
AB  - **Background**: Children treated in hospitals often experience high levels of anxiety and pain. The purpose of this meta-analysis was to analyze the effect of clown care in clinical nursing on children and to provide ideas for improving the clinical nursing care provided to children. 

**Methods**: Two authors searched PubMed, Embase, Clinical trials, Cochrane Library, Web of Science, CINAHL, Scopus, China National Knowledge Infrastructure (CNKI), Weipu, and Wanfang databases to identify randomized controlled trials (RCTs) related to clown care for children until 15 September 2023. The quality assessment of the included RCTs and the data extraction were performed by two researchers, and meta-analysis was carried out using RevMan5.4. 

**Results**: A total of 15 RCTs involving 2,252 children were finally included in this meta-analysis. The findings from this meta-analysis revealed that clown care was beneficial in reducing the pain [SMD = -0.96, 95% CI (-1.76, 0.16)], anxiety [SMD = -0.81, 95% CI (-1.16, -0.46)], and crying time [SMD = -1.09, 95% CI (-1.74, -0.44)] of children and the anxiety level of caregivers [SMD = -0.99, 95% CI (-1.95, -0.03)] (all P&#039;s &lt; 0.05). No significant publication biases were detected in the synthesized outcomes (all P&#039;s &gt; 0.05). 

**Conclusions**: Clown care is helpful in reducing the pain, anxiety, and crying time of children and the anxiety level of caregivers. However, additional high-quality studies with larger sample sizes are warranted to further analyze the role of clown care in clinical practice.
AN  - 38590768
AU  - Wang,
AU  - L.
AU  - Zhu,
AU  - J.
AU  - Chen,
AU  - T.
DB  - April 24.enl
DO  - /10.3389/fped.2024.1324283
L1  - internal-pdf://3103465794/Wang-2024-Clown care in the clinical nursing o.pdf
PY  - 2024
SP  - 1324283
T2  - Frontiers in Pediatrics
TI  - Clown care in the clinical nursing of children: a meta-analysis and systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffped.2024.1324283
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999578/pdf/fped-12-1324283.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - Context Mental ill-health is a common and growing issue, affecting 1 in 8 individuals or 970 million people worldwide in 2019. Histidine-containing dipeptides (HCDs) have been suggested to mitigate some aspects of mental ill-health, but a quantitative synthesis of the evidence is lacking. Therefore, a systematic review and meta-analysis of randomized controlled trials was conducted.Objective To summarize the evidence on the effects of HCDs on mental health outcomes.Data Source A systematic literature search was performed using electronic databases (Medline via Ovid, Embase via Ovid, Scopus, Google Scholar, and Cochrane) from inception to October, 2022.Data Extraction Two authors independently extracted data using a structured extraction format.Data Analysis Data analysis was performed using STATA version 17. Random-effects models were used, and heterogeneity was assessed using the I2 test. Quality appraisal was performed using the Cochrane risk-of-bias 2.0 tool and the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach.Conclusion 5507 studies were identified, with 20 studies fulfilling the inclusion criteria. Eighteen studies comprising 776 participants were included in the meta-analysis. HCD supplementation (anserine/carnosine, l-carnosine, beta-alanine) caused a significant reduction in depression scores measured with the Becks Depression Inventory (-0.79; 95% CI: -1.24, -0.35; moderate certainty on GRADE) when compared with placebo. An increase in quality-of-life scores measured with the 36-item Short-Form survey (SF-36) (0.65; 95% CI: 0.00, 1.30) and low certainty on GRADE in HCDs (anserine/carnosine, l-carnosine, beta-alanine) when compared with placebo were found. However, the rest of the outcomes did not show a significant change between HCD supplementation and placebo. Although the number of studies included in the meta-analysis was modest, a significant mean reduction was observed in depression score as well as an increase in quality-of-life score for the HCD group when compared with placebo. Most of the studies included had small sample sizes with short follow-up periods and moderate to high risk of bias, highlighting the need for further, well-designed studies to improve the evidence base.Systematic Review Registration PROSPERO registration no. CRD42017075354.
AN  - WOS:001192180000001
AU  - Kabthymer,
AU  - R.
AU  - H.
AU  - Saadati,
AU  - S.
AU  - Lee,
AU  - M.
AU  - Hariharan,
AU  - R.
AU  - Feehan,
AU  - J.
AU  - Mousa,
AU  - A.
AU  - de
AU  - Courten,
AU  - B.
DB  - April 24.enl
DO  - 10.1093/nutrit/nuae021
L1  - internal-pdf://1620585660/Kabthymer-2024-Carnosine_histidine-containing.pdf
PY  - 2024
SP  - 11
T2  - Nutrition Reviews
TI  - Carnosine/histidine-containing dipeptide supplementation improves depression and quality of life: systematic review and meta-analysis of randomized controlled trials
UR  - &lt;Go to ISI&gt;://WOS:001192180000001
UR  - https://watermark.silverchair.com/nuae021.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA34wggN6BgkqhkiG9w0BBwagggNrMIIDZwIBADCCA2AGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMQ33c-nFjKIwyNK6ZAgEQgIIDMabaKTOfJKRl3tAzTBomYXJe344yKXnpPafxgcwfvZhsTRay7JjZR_JZy9xIxnylFNkzwbwucaxbjKzTJIWfApIlbM-bKC96kGwI7d2XBwG6pRpUgnBzjuRZk5zHv3X68avrNtGhJ1IzN9K364aTOKrOzE4F13np7aFozXQJw_yh5GipNySS0Hr3IfByIqJBMA1XV7qwfb5mhNlgzNgMjhGeb10pPyM38dG6kkhx7BK90SiFUGKL8TC2gjNcIJI2_a4JxBHgAX3gJ-mY1FwoCkk3E3D34tEUPzv9mgal5AL33amTlLLIIsiWQ28eR6PpzyYfQir9-_kjLZMrae2uoq_6YiJ4_X6Mq08oyzjW1f-nIb-hEmC8LWjx-d83kvQkwvi3BXH7B6R0wlT-L2PNfhQkdCWEwlytR-hZvXRX9zgop0q20Nw3ghQTA8nyvuDFNte_U2GLMfeT4uQJZjGy1Dw2MVLrBat41-2VZd2kbQzSQ4fqxoeTgVa9vOZmKV3X5LfLur6QNS7QUUvPcMsqZpQovAZ_mAea40YUZWgEAjeU2DALXCoOGcCQthQ61SIdk2GmnxmXA9IIPimmtiTXKVAIN-PY-8ALRDMQMrZmPxdeHSFbgj1JkhLjlGjkU6Fs9Cflb-3AoXqzD7v5CUXZSPGx5hXJXDDAw9GkLvnjFVkr3apYgzGLQptht2Vqq9fLye0xMJ5dj9NYO9HO7tmSA6n-2na_zv-tL6v8Ek73kFFy_2zJT_ZKiE12LkKtj5tPhc3yr9iQ5f6W-sHgGrWQRfbLlpUFRBKa0H-T7ItXXXRcVdLm5b4Pj7W5byRggJWP_TpgKaqA0BX7tjDg0P65DJ-NBWH4MXcPcXeE-P2jmVE2tdvnmjZUYlilu3qqqLJRccvnHsg4Rl1EjhRhTgt39hxplyLZsbef-DJh9URztg4w3W2vupnGfIb_PKGvSUY45TbiySH36ym2CiPS4_tQsfefJkaWAedOazVvwE75yyIMtr84yCW8vwz3-NSuEd9VKV5RFWVEKJhLOFNI0SoO7oQ4WIUd_Ay1UzaQC7_PhqnxQN5H1oFu22DSyerR8AO8pS0
ER  -
TY  - JOUR
AB  - BACKGROUND: Researches have found that alteration of intestinal flora may be closely related to the development of autism spectrum disorder (ASD). However, whether probiotics supplementation has a protective effect on ASD remains controversial. This meta-analysis aimed to analyze the outcome of probiotics in the treatment of ASD children. 

METHODS: The Pubmed, Cochrane Library, Web of Science and Embase were searched until Sep 2022. Randomized controlled trials (RCTs) relevant to the probiotics and placebo treatment on ASD children were screened. Quality assessment of the included RCTs was evaluated by the Cochrane collaboration&#039;s tool. The primary outcomes were ASD assessment scales, including ABC (aberrant behavior checklist) and CBCL (child behavior checklist) for evaluating the behavior improvement, SRS (social responsiveness scale) for social assessment, DQ (developmental quotient) for physical and mental development and CGI-I (clinical global impression improvement) for overall improvement. The secondary outcome was total 6-GSI (gastrointestinal severity index). 

RESULTS: In total, 6 RCTs from 6 studies with 302 children were included in the systemic review. Total 6-GSI (MD=-0.59, 95%CI [-1.02,-0.17], P &lt; 0.05) decreased significantly after oral administration of probiotics. Whereas, there was no statistical difference in ABC, CBCL, SRS, DQ and CGI-I between probiotics and placebo groups in ASD children. 

CONCLUSION: Probiotics treatment could improve gastrointestinal symptoms, but there was no significant improvement in ASD.
AN  - 38902804
AU  - Zeng,
AU  - P.
AU  - Zhang,
AU  - C.
AU  - Z.
AU  - Fan,
AU  - Z.
AU  - X.
AU  - Yang,
AU  - C.
AU  - J.
AU  - Cai,
AU  - W.
AU  - Y.
AU  - Huang,
AU  - Y.
AU  - F.
AU  - Xiang,
AU  - Z.
AU  - J.
AU  - Wu,
AU  - J.
AU  - Y.
AU  - Zhang,
AU  - J.
AU  - Yang,
AU  - J.
DB  - Juni 24.enl
DO  - /10.1186/s13052-024-01692-z
L1  - internal-pdf://0482242005/Zeng-2024-Effect of probiotics on children wit.pdf
PY  - 2024
SP  - 120
T2  - Italian Journal of Pediatrics
TI  - Effect of probiotics on children with autism spectrum disorders: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1186%2fs13052-024-01692-z
UR  - https://ijponline.biomedcentral.com/counter/pdf/10.1186/s13052-024-01692-z.pdf
VL  - 50
ER  -
TY  - JOUR
AB  - Fidget devices are tools that purportedly help students focus on a designated task while moving their bodies. Devices such as spinners, putty, and stability balls are increasingly being used within school settings to help students academically and behaviorally. However, the research behind fidget spinners is inconclusive. The current study provides a systematic review and meta-analysis of the use of fidget devices to increase academic and behavioral abilities within group classroom settings. Ten studies with a total of 509 participants were included in the analysis. Half of the studies used stability balls as the fidget device while the other half used handheld fidget devices (fidget spinners or stress ball). A multilevel meta-analysis model with robust variance estimation with random effects was used to determine an omnibus effect size and a mixed effects meta-regression model with robust variance estimation was used for moderator analyses. Results indicate that the effects of fidget devices vary widely with individual study effects ranging from -2.98 to 1.15 and an overall Hedges&#039; g effect size of -0.014. There were no significant moderating variables. Discussion explores the slightly negative overall effect when using fidget devices and the implications of using fidget devices within the school setting.Impact StatementThe benefits of using fidget devices as tools to improve either academics or behavior are negligible when used with large groups of students, even though they are inexpensive, easy to use and typically well-liked by students. It is important not to replace established, evidence-based interventions with fidget devices, which are not fully supported by research.
AN  - WOS:001334678700001
AU  - Schoenen,
AU  - E.
AU  - C.
AU  - Alsip,
AU  - B.
AU  - S.
AU  - Martinez,
AU  - J.
AU  - C.
AU  - Grekov,
AU  - P.
AU  - Aspiranti,
AU  - K.
AU  - B.
AU  - Hulac,
AU  - D.
AU  - M.
DB  - November 2024.enl
DO  - 10.1080/2372966x.2024.2411576
L1  - internal-pdf://0550337544/Schoenen-2024-A Meta-Analysis of Fidget Device.pdf
PY  - 2024
SP  - 13
T2  - School Psychology Review
TI  - A Meta-Analysis of Fidget Devices as Academic and Behavioral Interventions
UR  - &lt;Go to ISI&gt;://WOS:001334678700001
UR  - https://www.tandfonline.com/doi/full/10.1080/2372966X.2024.2411576
UR  - https://www.tandfonline.com/doi/pdf/10.1080/2372966X.2024.2411576
ER  -
TY  - JOUR
AB  - Background: Numerous experimental studies have shown that exercise can serve as an intervention with beneficial effects on children and adolescents with autism. However, a systematic review on the specific areas affected has not been conducted. 

Methods: Preliminary research sources were obtained by searching four databases, and two researchers independently screened the literature that met the study criteria. The study was conducted under the guidelines of the Cochrane Handbook for Systematic Reviews of Interventions. 

Results: 37 studies were included in the final analysis, of which 9 studies were quantitatively synthesized and 28 studies were qualitatively analyzed. Exercise interventions have positive effects on motor performance, cognitive function, individual and social relationships, behavioral problems, physical health, and brain function in children and adolescents with autism. The results of the meta-analysis indicate that exercise can effectively improve social skills [SMD=-0.53, 95%CI (-0.76, -0.3), P=0.000]. 

Conclusions: Long-term, regular, chronic exercise is beneficial for children and adolescents with autism, particularly in the area of social skills. <b>Systematic review registration</b>: https://www.crd.york.ac.uk/prospero PROSPERO, identifier CRD42024554530.
AN  - 39435130
AU  - Jia,
AU  - M.
AU  - Zhang,
AU  - J.
AU  - Pan,
AU  - J.
AU  - Hu,
AU  - F.
AU  - Zhu,
AU  - Z.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fpsyt.2024.1462601
L1  - internal-pdf://1551693476/Jia-2024-Benefits of exercise for children and.pdf
PY  - 2024
SP  - 1462601
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Benefits of exercise for children and adolescents with autism spectrum disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffpsyt.2024.1462601
UR  - https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1462601/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - BACKGROUND: Major depressive disorder (MDD) is highly prevalent in youth. Conventional treatment paradigms primarily involve selective serotonin reuptake inhibitors (SSRIs) and psychotherapy, yet a significant proportion of this population exhibits treatment-resistant depression (TRD). In adults, interventional therapies like Electroconvulsive Therapy (ECT), repetitive Transcranial Magnetic Stimulation (rTMS), and ketamine have shown promise for TRD, but their comparative efficacy remains underexplored in Adolescent and pediatric population. This systematic review and meta-analysis aims to assess the relative effectiveness of ECT, rTMS, and ketamine in treating TRD among adolescents. 

METHODS: Following PRISMA guidelines, we systematically searched databases for studies of ECT, rTMS, or ketamine for treatment-resistant depression in youth ages 10-24. Three reviewers independently screened for inclusion based on predefined criteria. Included observational and randomized controlled trials reported depression symptoms with measures like HDRS and MADRS in youth treated with ECT, rTMS, or ketamine. Two reviewers extracted data on interventions, patients, and depression symptom outcomes. Chance-adjusted inter-reviewer agreement was calculated. For meta-analysis, we pooled standardized mean differences (SMDs) in depression scores using random effects models and assessed heterogeneity with I2 statistics.

RESULTS: Meta-analysis of 10 observational studies examined SMD in depression scores for treatment resistant depression patients treated with ECT, ketamine, or rTMS. Patients treated with ECT had a significantly lower SMD of 1.99 (95 % CI 0.92-3.05, p &lt; 0.001) compared to baseline. Patients treated with ketamine also had a significantly lower SMD of 1.58 (95 % CI 1.04-2.12, p &lt; 0.001). Patients treated with rTMS had the lowest SMD of 2.79 (95 % CI 0.79-4.80, p = 0.006). There was no significant difference between the three groups overall (p &gt; 0.05). Comparative analysis between ECT and ketamine found no significant difference in SMD (p = 0.387). Comparison of ECT versus rTMS found a significant difference in SMD favoring rTMS (p = 0.004). Comparison of ketamine versus rTMS suggested a potential difference in SMD favoring rTMS (p = 0.058). In summary, rTMS resulted in significantly larger reductions in depression scores than ECT, and potentially larger reductions than ketamine. 

CONCLUSIONS: This meta-analysis illustrates the ability of rTMS, ECT, and ketamine to improve depression in youth. rTMS resulted in the largest improvements, highlighting its potential as a first-line treatment for pediatric treatment-resistant depression given its favorable side effect profile compared to ECT. Further research directly comparing these modalities is needed.
AN  - 39226935
AU  - Faries,
AU  - E.
AU  - Mabe,
AU  - L.
AU  - A.
AU  - Franzen,
AU  - R.
AU  - L.
AU  - Murtaza,
AU  - S.
AU  - Nathani,
AU  - K.
AU  - Ahmed,
AU  - B.
AU  - Prokop,
AU  - L.
AU  - Mohammed,
AU  - K.
AU  - Ahmed,
AU  - A.
AU  - T.
DB  - September 2024.enl
DO  - /10.1016/j.jad.2024.08.212
L1  - internal-pdf://0704599709/1-s2.0-S0165032724014459-main.cleaned.pdf
PY  - 2024
SP  - 519-529
T2  - Journal of Affective Disorders
TI  - Interventional approaches to treatment resistant depression (DTR) in children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jad.2024.08.212
VL  - 367
ER  -
TY  - JOUR
AB  - Long-chain n-3 polyunsaturated fatty acid (PUFA) consumption in maternal and infants has been positively associated with cognitive and visual development. Tails even meta-analysis showed mixed results. To evaluate the effects of maternal and infant n-3 PUFA supplementation on childhood psychomotor and cognitive development, PubMed, Embase, the Cochrane Library, PsycINFO and clinicaltrials.gov were searched. Randomized controlled trials were included to evaluate the effect on child cognitive and psychomotor outcomes of n-3 PUFA supplementation in mothers or infants (age &lt;= 2 years). Findings were pooled with mean differences (MD) with 95% confidence intervals (95% CIs). Heterogeneity was explored using I&lt;sup&gt;2&lt;/sup&gt; and subgroup analyses, stratified for maternal (pregnancy and/or lactation) and infant (preterm infant and term infant). We identified 47 articles, with 14 trials on mothers and 33 on infants. Pooled results showed that infants&#039; mental development index (MDI) increased with n-3 PUFA supplementation (MD = 2.91, 95% CI: 1.32-4.51, I&lt;sup&gt;2&lt;/sup&gt; = 65.1%). Subgroup analysis of MDI also demonstrated a benefit in preterm infants (MD = 4.16, 95% CI: 1.40-6.93, I&lt;sup&gt;2&lt;/sup&gt; = 49.5%) and term infants (MD = 2.28, 95% CI: 0.27-4.29, I&lt;sup&gt;2&lt;/sup&gt; = 70.1%). No significant association was found in subgroup analyses of supplementation to mothers during pregnancy or lactation period. Supplementation did not increase the psychomotor development index (PDI) in the mother or infant group. Language composite score increased for infants whose mothers accepted supplementation in pregnancy or breastfeeding (MD = 8.57, 95% CI: 5.09-12.04, I&lt;sup&gt;2&lt;/sup&gt; = 70.2%). The cognitive composite score did not improve in any subgroup. Intelligence Quotient (IQ) increased in the infants&#039; group with n-3 PUFA supplementation (MD = 2.54, 95% CI: 0.45-4.63, I&lt;sup&gt;2&lt;/sup&gt; = 66.0%). Furthermore, IQ in term infants also improved (MD = 2.91, 95% CI: 0.24-5.57, I&lt;sup&gt;2&lt;/sup&gt; = 69.2%). The funnel plot and Egger&#039;s test confirmed no publication bias in any endpoints. Supplementation with n-3 PUFA during pregnancy or breastfeeding in mothers has increased language abilities. Furthermore, direct supplementation in term infants can improve intelligence in later childhood. However, insufficient evidence supports the claim that supplementation improves cognitive abilities.
AN  - 39609259
AU  - Liu,
AU  - Y.
AU  - Zhong,
AU  - L.
AU  - Sun,
AU  - Z.
AU  - Feng,
AU  - Y.
AU  - Ding,
AU  - Q.
AU  - Zhang,
AU  - Y.
DB  - Desember 2024.enl
DO  - /10.1111/mcn.13767
L1  - internal-pdf://0582220009/Liu-2024-N-3 Fatty Acid Supplementation in Mot.pdf
PY  - 2024
SP  - e13767
T2  - Maternal &amp; Child Nutrition
TI  - N-3 Fatty Acid Supplementation in Mothers and Infants for Childhood Psychomotor and Cognitive Development: An Updated Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1111%2fmcn.13767
UR  - https://onlinelibrary.wiley.com/doi/10.1111/mcn.13767
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/mcn.13767?download=true
ER  -
TY  - JOUR
AB  - Background: Depression poses significant threats to adolescents&#039; health globally. Research has shown the potential of mind-body therapies to alleviate depression, but limited studies have directly compared the therapeutic effects of different types of mind-body therapies on adolescent depression and the optimal therapy remain unclear. Therefore, we conducted a systematic review and network meta-analysis of randomized controlled trials that met the inclusion criteria to explore the effectiveness of different types of mind-body therapies as interventions to improve depression among adolescents, and to identify the most effective interventions. 

Methods: A comprehensive search of databases including PubMed, EMBASE, Cochrane Library, Web of Science, and Scopus up to January 2024 was conducted to assess the impact of mind-body therapies on depression among adolescents. The risk of bias of the included studies was evaluated using Cochrane Review Manager 5.4. STATA 18.0 was used for network meta-analysis. The node-splitting method was used to test the local inconsistency of the network meta-analysis. Funnel plots and the Egger&#039;s test were utilized to assess the potential impact of bias in this study. 

Result: This network meta-analysis included 9 randomized controlled trials involving a total of 955 subjects. The results indicated that yoga, dance therapy and Tai Chi were more effective than other mind-body therapies in reducing symptoms of depression among adolescents. Specifically, according to the SUCRA ranking, yoga was rated to be the optimal intervention for adolescents with depression (SCURA: 82.2%), followed by dance therapy (SCURA: 77.5%) and Tai Chi (SCURA: 64.9%). 

Conclusion: This study revealed that mind-body therapies have positive effects on improving depression among adolescents. Yoga may be the most effective intervention among the different types of mind-body therapies. However, due to the small sample size of patients included, the certainty of the results was limited to some extent. Therefore, further investigation is necessary to strengthen the evidence base when more relevant studies become available. <b>Systematic review registration</b>: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42024508774.
AN  - 39050611
AU  - Luo,
AU  - S.
AU  - Mei,
AU  - Z.
AU  - Fang,
AU  - G.
AU  - Mu,
AU  - G.
AU  - Zhang,
AU  - X.
AU  - Luo,
AU  - S.
DB  - Juli 2024.enl
DO  - /10.3389/fpubh.2024.1431062
L1  - internal-pdf://2196126178/Luo-2024-Effects of mind-body therapies on dep.pdf
PY  - 2024
SP  - 1431062
T2  - Frontiers in Public Health
TI  - Effects of mind-body therapies on depression among adolescents: a systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.3389%2ffpubh.2024.1431062
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11266190/pdf/fpubh-12-1431062.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: To examine the magnitude of placebo response in randomized controlled trials (RCTs) of medications for Tourette&#039;s disorder. **METHOD**: CENTRAL, Embase, PubMed, PsycInfo, Web of Science, WHO ICTRP, and ClinicalTrials.gov databases were searched up to September, 2023 to identify placebo-controlled RCTs assessing pharmacological interventions for Tourette&#039;s disorder. Standardized mean change and standardized mean difference were calculated for within-group (placebo, drug) and between-group (drug-placebo) change in tics. Data were pooled in random-effects meta-analysis. Meta-regressions were performed to identify study-level characteristics that could be differentially associated with placebo, drug, and drug-placebo response. **RESULTS**: Literature searches identified 13,775 records, and 50 RCTs involving 1,566 participants were included in the placebo meta-analysis. Placebo response was medium to large (standardized mean change: -0.62; 95% CI: -0.75, -0.5; I&lt;sup&gt;2&lt;/sup&gt; = 76%; tau&lt;sup&gt;2&lt;/sup&gt; = 0.14). Several factors were associated with larger placebo responses (eg, non-US RCT, industry sponsorship, number of centers and participants). However, there was a moderate-to-high correlation between placebo and drug response (rho = 0.66; 95% CI: 0.47, 0.79), and factors associated with larger placebo response were also generally associated with larger drug responses. There was not a significant correlation between placebo response and drug-placebo differences (rho = -0.05; 95% CI: -0.32, 0.22), and factors associated with larger placebo response generally did not interfere in drug-placebo differences. **CONCLUSION**: The magnitude of placebo response in Tourette&#039;s disorder may be large, but similar to that in other child and adolescent psychiatric conditions. Clinical researchers may manipulate study-level factors to diminish placebo response (eg, carefully selecting study sites and keeping them at the minimum feasibility). However, drug-placebo differences may not increase as drug response will likely diminish as well. **STUDY PREREGISTRATION INFORMATION**: Comparative Efficacy, Tolerability, and Acceptability of Pharmacological Interventions for Chronic Tic Disorders Including Tourette&#039;s Syndrome in Children, Adolescents, and Adults: Protocol for a Systematic Review and Network Meta-analysis; https://www.crd.york.ac.uk; CRD42022296975. **DIVERSITY &amp; INCLUSION STATEMENT**: One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented sexual and/or gender groups in science. One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science.
AN  - 39505141
AU  - Macul
AU  - Ferreira
AU  - de
AU  - Barros,
AU  - P.
AU  - Farhat,
AU  - L.
AU  - C.
AU  - Behling,
AU  - E.
AU  - Nasir,
AU  - M.
AU  - Landeros-Weisenberger,
AU  - A.
AU  - Bloch,
AU  - M.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1016/j.jaac.2024.10.011
L1  - internal-pdf://2399411100/c548b48e-4b6f-4d68-b982-33641d4b0d95.pdf
PY  - 2024
SP  - 04
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Systematic Review and Meta-Analysis: Placebo Response in Randomized Controlled Trials of Tourette&#039;s Disorder Medications
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jaac.2024.10.011
UR  - https://www.sciencedirect.com/science/article/pii/S0890856724019737?via%3Dihub
VL  - 04
ER  -
TY  - JOUR
AB  - Developing social competence for preschoolers is an important area for early intervention, especially for young children with emotional and behavioral issues. This single case meta-analysis focused on examining the literature base for social skills interventions for preschoolers. A systematic search of the literature yielded 33 single-case studies on social skills interventions for preschoolers. Results from the aggregated single case studies using a baseline corrected Tau-U indicated a moderate to large effect (Baseline Corrected Tau = 0.66). Moderator analysis results showed gender and intervention format were statistically significant moderators for the intervention effect. Limitations and directions for future research were discussed within the context of social-behavioral research and early intervention in preschool settings. Preschool teachers can be effective social skills intervention implementers with adequate trainings. Social skills interventions delivered in large group are possibly more effective than those delivered in small group or individually in improving preschoolers&#039; social skills. Generally speaking, social skills interventions are more effective for preschool girls than boys.
AN  - WOS:001236287500001
AU  - Dong,
AU  - X.
AU  - Burke,
AU  - M.
AU  - D.
AU  - Sanchez,
AU  - L.
AU  - Bowman-Perrott,
AU  - L.
DB  - Juni 24.enl
DO  - 10.1002/pits.23248
L1  - internal-pdf://3937824400/Dong-2024-Social skills interventions in presc.pdf
PY  - 2024
SP  - 18
T2  - Psychology in the Schools
TI  - Social skills interventions in preschool settings: A meta-analysis of SCR studies
UR  - &lt;Go to ISI&gt;://WOS:001236287500001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pits.23248?download=true
ER  -
TY  - JOUR
AB  - **Background:** 
Early childhood intervention is a form of intervention aimed at children to overcome difficulties in different areas of their development after birth. There are multiple early intervention programmes, but only a few studies assess their efficacy using data. 

**Objective:** 
A systematic review and meta-analysis of early intervention programmes was carried out. Method: Inclusion criteria were considered to be empirical studies, with outcome data on children between 0 and 6 years of age with various developmental problems. The review was conducted in nine databases. 

**Results:** 
Of the total number of studies from 2000 to 2021 in English and Spanish, 40 studies were included that looked at the efficacy of the programmes. Of these, 19 used comparisons with a control group, and 13 used single-subject designs, as well as other designs. The programmes were very diverse, mostly based on behavioural procedures, and aimed at promoting the development of specific areas. The quality of the studies is medium-high. The meta-analysis included 18 studies with a mean effect size d = 0.45 (CI = 0.18, 0.67), with high sample heterogeneity and low study selection bias. 

**Conclusions:** 
Early childhood interventions have a medium and positive efficacy on the skills and abilities of children with developmental problems. The limitations of the reviewed studies are discussed, as well as the need for well-defined programmes, long-term measurements, and comparisons of different types of programmes among them.
AN  - WOS:001138441600001
AU  - G&oacute;mez-Cotilla,
AU  - R.
AU  - Lopez-de-Uralde-Selva,
AU  - M.
AU  - Valero-Aguayo,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.5093/psed2024a1
L1  - internal-pdf://3021351330/G&oacute;mez-Cotilla-2024-Efficacy of Early Intervent.pdf
PY  - 2024
SP  - 1-10
T2  - Psicologia Educativa
TI  - Efficacy of Early Intervention Programmes: Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001138441600001
UR  - https://journals.copmadrid.org/psed/archivos/1135_755X_psed_30_1_0001.pdf
VL  - 30
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Public interest in the potential benefits of white, pink, and brown noise for attention-deficit/hyperactivity disorder (ADHD) has recently mushroomed. White noise contains all frequencies of noise and sounds like static; pink or brown noise has more power in the lower frequencies and may sound, respectively, like rain or a waterfall. This meta-analysis evaluated effects on laboratory tasks in individuals with ADHD or elevated ADHD symptoms. 

**METHOD**: Eligible studies reported on participants with diagnosis of ADHD or elevated symptoms of ADHD who were assessed in a randomized trial using laboratory tasks intended to measure aspects of attention or academic work involving attention or executive function while exposed to white, pink, and brown noise and compared with a low/no noise condition. Two authors independently reviewed and screened studies for eligibility. A random-effects meta-analysis was conducted with preplanned moderator analyses of age, diagnostic status, and task type. Publication bias was evaluated. The GRADE tool was used to assess certainty of the evidence. Sensitivity analyses were conducted to evaluate robustness. 

**RESULTS**: Studies of children and college-age young adults with ADHD or ADHD symptoms (k = 13, N = 335) yielded a small but statistically significant benefit of white and pink noise on task performance (g = 0.249, 95% CI [0.135, 0.363], p &lt; .0001). No studies of brown noise were identified. Heterogeneity was minimal, and moderators were nonsignificant; results survived sensitivity tests, and no publication bias was identified. In non-ADHD comparison groups (k = 11, N = 335), white and pink noise had a negative effect (g = -0.212, 95% CI [-0.355, -0.069], p = .0036). 

**CONCLUSION**: White and pink noise provide a small benefit on laboratory attention tasks for individuals with ADHD or high ADHD symptoms, but not for non-ADHD individuals. This article addresses theoretical implications, cautions, risks, and limitations. <b>STUDY PREREGISTRATION INFORMATION</b>: White Noise for ADHD: A Systematic Review And Meta-analysis; https://www.crd.york.ac.uk/prospero; CRD42023393992.
AN  - 38428577
AU  - Nigg,
AU  - J.
AU  - T.
AU  - Bruton,
AU  - A.
AU  - Kozlowski,
AU  - M.
AU  - B.
AU  - Johnstone,
AU  - J.
AU  - M.
AU  - Karalunas,
AU  - S.
AU  - L.
DB  - Mars 24.enl
DO  - /10.1016/j.jaac.2023.12.014
L1  - internal-pdf://1064289993/1-s2.0-S0890856724000741-main.cleaned.pdf
PY  - 2024
SP  - 28
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Systematic Review and Meta-analysis: Do White Noise and Pink Noise Help With Attention in Attention-Deficit/Hyperactivity Disorder?
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jaac.2023.12.014
UR  - https://www.sciencedirect.com/science/article/pii/S0890856724000741?via%3Dihub
VL  - 28
ER  -
TY  - JOUR
AB  - BACKGROUND: The incidence of self-harm and suicidal behaviour in adolescents is increasing. Considering the great impact in this population, an actualization of the evidence of those psychological treatment&#039;s excellence for suicidal behaviour. Thus, the aim of this paper is to compile the available evidence on the effectiveness of cognitive behavioural therapy and dialectical behavioural therapy in preventing self-harm and suicidal behaviour in adolescents. 

METHODS: A umbrella review was carried out, different databases (PubMed, CINAHL, Cochrane Library, Psyinfo, Embase, Web of Science, Scopus and Google Scholar) were consulted. The 16-item measurement tool to assess systematic reviews-2 (AMSTAR-2) were performed by two independent reviewers and any discrepancies were resolved by consensus. The Rayyan-Qatar Computing Research Institute was used for the screening process. 

RESULTS: Nine systematic reviews were included. Cognitive Behavioural Therapy appears to reduce the incidence of suicide-related events compared with treatment as usual, compared to usual treatment (which usually consists of drugs and talk therapy) especially when combined with fluoxetine. Dialectical behavioural therapy seems to be associated with a reduction in suicidal ideation and self-harm. 

CONCLUSIONS: Although the results found show results with high heterogeneity. The evidence on cognitive behavioural therapy and dialectical behavioural therapy for suicide prevention, self-harm and suicide ideation in adolescents seems to show positive results. Considering, the special population and great impact, further research is needed and comparable studies should be sought that allow to set up robust recommendations.
AN  - 39129696
AU  - Torralba-Suarez,
AU  - C.
AU  - Olry-de-Labry-Lima,
AU  - A.
DB  - August 2024.enl
DO  - /10.62641/aep.v52i4.1631
L1  - internal-pdf://0694183578/Torralba-Suarez-2024-An Umbrella Review of Cog.pdf
PY  - 2024
SP  - 549-560
T2  - Actas Espanolas de Psiquiatria
TI  - An Umbrella Review of Cognitive Behavioural and Dialectical Behavioural Therapies to Treat Self-Harm and Suicidal Behaviour in Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.62641%2faep.v52i4.1631
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11319749/pdf/ActEsp-52-4-549-560.pdf
VL  - 52
ER  -
TY  - JOUR
AB  - **Background**
Infants born preterm are at increased risk of cognitive and motor impairments compared with infants born at term. Early developmental interventions for preterm infants are targeted at the infant or the parent‐infant relationship, or both, and may focus on different aspects of early development. They aim to improve developmental outcomes for these infants, but the long‐term benefits remain unclear. This is an update of a Cochrane review first published in 2007 and updated in 2012 and 2015.

**Objectives**

Primary objective

To assess the effect of early developmental interventions compared with standard care in prevention of motor or cognitive impairment for preterm infants in infancy (zero to &lt; three years), preschool age (three to &lt; five years), and school age (five to &lt; 18 years).

Secondary objective

To assess the effect of early developmental interventions compared with standard care on motor or cognitive impairment for subgroups of preterm infants, including groups based on gestational age, birthweight, brain injury, timing or focus of intervention and study quality.

**Search methods**
We searched CENTRAL, MEDLINE, Embase, CINAHL, PsycINFO and trial registries in July 2023. We cross‐referenced relevant literature, including identified trials and existing review articles.

**Selection criteria**
Studies included randomised, quasi‐randomised controlled trials (RCTs) or cluster‐randomised trials of early developmental intervention programmes that began within the first 12 months of life for infants born before 37 weeks&#039; gestational age (GA). Interventions could commence as an inpatient but had to include a post discharge component for inclusion in this review. Outcome measures were not prespecified, other than that they had to assess cognitive outcomes, motor outcomes or both. The control groups in the studies could receive standard care that would normally be provided.

**Data collection and analysis**
Data were extracted from the included studies regarding study and participant characteristics, timing and focus of interventions and cognitive and motor outcomes. Meta‐analysis using RevMan was carried out to determine the effects of early developmental interventions at each age range: infancy (zero to &lt; three years), preschool age (three to &lt; five years) and school age (five to &lt; 18 years) on cognitive and motor outcomes. Subgroup analyses focused on GA, birthweight, brain injury, time of commencement of the intervention, focus of the intervention and study quality. We used standard methodological procedures expected by Cochrane to collect data and evaluate bias. We used the GRADE approach to assess the certainty of evidence.

**Main results**
Forty‐four studies met the inclusion criteria (5051 randomly assigned participants). There were 19 new studies identified in this update (600 participants) and a further 17 studies awaiting outcomes. Three previously included studies had new data. There was variability in the focus and intensity of the interventions, participant characteristics, and length of follow‐up. All included studies were either single or multicentre trials and the number of participants varied from fewer than 20 to up to 915 in one study. The trials included in this review were mainly undertaken in middle‐ or high‐income countries. The majority of studies commenced in the hospital, with fewer commencing once the infant was home. The focus of the intervention programmes for new included studies was increasingly targeted at both the infant and the parent‐infant relationship. The intensity and dosages of interventions varied between studies, which is important when considering the applicability of any programme in a clinical setting.

Meta‐analysis demonstrated that early developmental intervention may improve cognitive outcomes in infancy (developmental quotient (DQ): standardised mean difference (SMD) 0.27 standard deviations (SDs), 95% confidence interval (CI) 0.15 to 0.40; P &lt; 0.001; 25 studies; 3132 participants, low‐certainty evidence), and improves cognitive outcomes at preschool age (intelligence quotient (IQ); SMD 0.39 SD, 95% CI 0.29 to 0.50; P &lt; 0.001; 9 studies; 1524 participants, high‐certainty evidence). However, early developmental intervention may not improve cognitive outcomes at school age (IQ: SMD 0.16 SD, 95% CI ‐0.06 to 0.38; P = 0.15; 6 studies; 1453 participants, low‐certainty evidence). Heterogeneity between studies for cognitive outcomes in infancy and preschool age was moderate and at school age was substantial. Regarding motor function, meta‐analysis of 23 studies showed that early developmental interventions may improve motor outcomes in infancy (motor scale DQ: SMD 0.12 SD, 95% CI 0.04 to 0.19; P = 0.003; 23 studies; 2737 participants, low‐certainty evidence). At preschool age, the intervention probably did not improve motor outcomes (motor scale: SMD 0.08 SD, 95% CI ‐0.16 to 0.32; P = 0.53; 3 studies; 264 participants, moderate‐certainty evidence). The evidence at school age for both continuous (motor scale: SMD ‐0.06 SD, 95% CI ‐0.31 to 0.18; P = 0.61; three studies; 265 participants, low‐certainty evidence) and dichotomous outcome measures (low score on Movement Assessment Battery for Children (ABC) : RR 1.04, 95% CI 0.82 to 1.32; P = 0.74; 3 studies; 413 participants, low‐certainty evidence) suggests that intervention may not improve motor outcome.

The main source of bias was performance bias, where there was a lack of blinding of participants and personnel, which was unavoidable in this type of intervention study. Other biases in some studies included attrition bias where the outcome data were incomplete, and inadequate allocation concealment or selection bias. The GRADE assessment identified a lower certainty of evidence in the cognitive and motor outcomes at school age. Cognitive outcomes at preschool age demonstrated a high certainty due to more consistency and a larger treatment effect.

**Authors&#039; conclusions**
Early developmental intervention programmes for preterm infants probably improve cognitive and motor outcomes during infancy (low‐certainty evidence) while, at preschool age, intervention is shown to improve cognitive outcomes (high‐certainty evidence). Considerable heterogeneity exists between studies due to variations in aspects of the intervention programmes, the population and outcome measures utilised. Further research is needed to determine which types of early developmental interventions are most effective in improving cognitive and motor outcomes, and in particular to discern whether there is a longer‐term benefit from these programmes.
AN  - CD005495
AU  - Orton,
AU  - J.
AU  - Doyle,
AU  - L.
AU  - W.
AU  - Tripathi,
AU  - T.
AU  - Boyd,
AU  - R.
AU  - Anderson,
AU  - P.
AU  - J.
AU  - Spittle,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/14651858.CD005495.pub5
KW  - *Brain Injuries
KW  - *Cognitive Dysfunction [prevention &amp; control]
KW  - Adolescent
KW  - Birth Weight
KW  - Child
KW  - Child, Preschool
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - Infant, Premature
KW  - Patient Discharge
L1  - internal-pdf://0974994245/Orton_et_al-2024-Cochrane_Database_of_Systemat.pdf
N1  - [Neonatal]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants
UR  - http://dx.doi.org/10.1002/14651858.CD005495.pub5
ER  -
TY  - JOUR
AB  - Background: Adolescence is also accompanied by ongoing mood changes (relative to childhood and adulthood), which can trigger more extreme negative emotional responses. Physical exercise alleviates negative emotions and reduces the risk of mental illness. However, the effect of physical exercise on negative emotions in adolescents is unclear, so it is valuable to synthesize previous studies with meta-analysis. 

Objective: To examine the influence of physical exercise (PE) intervention on negative emotions in adolescents aged 10 to 19 years. 

Methods: We retrieved the articles from PubMed, Web of Science, EBSCO, Cochrane, and Embase up to April 11, 2024. The main search terms were physical exercise, negative emotions, adolescents, randomized controlled trials. The meta-analysis was conducted using Review Manager 5.3. A random-effects model was employed to calculate the standardized mean difference (SMD) and 95% confidence interval (CI). Subgroups were analysed as the type of negative emotions, type of control group, intervention type, duration, time, frequency. 

Results: The PE intervention group exhibited a significantly superior improvement in alleviating negative emotions compared to the control group (SMD = -0.59, 95% CI: -0.92 to -0.26, p &lt; 0.01, Z = 3.50, I2 = 95%). PE was particularly effective in mitigating adolescent depression (SMD = -0.67, 95% CI = -1.07 to -0.28, p &lt; 0.01, I2 = 96%) but did not yield significant results in reducing adolescent anxiety (SMD = -0.29, 95% CI = -0.63 to 0.05, p = 0.10, I2 = 95%). 

Conclusion: PE intervention can ameliorate negative emotions in adolescents. <b>Systematic Review Registration</b>: https://www.crd.york.ac.uk/prospero/, identifier CRD42024534375.
AN  - 39600789
AU  - Wang,
AU  - T.
AU  - Li,
AU  - W.
AU  - Deng,
AU  - J.
AU  - Zhang,
AU  - Q.
AU  - Liu,
AU  - Y.
DB  - November 2024.enl
DO  - /10.3389/fpsyt.2024.1457931
L1  - internal-pdf://3812589115/Wang-2024-The influence of physical exercise o.pdf
PY  - 2024
SP  - 1457931
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - The influence of physical exercise on negative emotions in adolescents: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffpsyt.2024.1457931
UR  - https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1457931/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - As students in out-of-home care are at high risk of school failure, it is imperative to promote academic skills through effective interventions. A systematic review of interventions aimed at improving academic achievement of out-of-home care was conducted to identify the most effective strategies for supporting literacy and mathe-matical skills. Data from 21 interventions, involving 2,049 children in out-of-home care, were synthesized through meta-analysis. Overall, the interventions had a significant impact on literacy (g = .242, 95 % CI [.180, .305], k = 21) and mathematical skills (g = .229, 95 % CI [.115, .343], p &lt;.001, k = 14). Three main direct academic support strategies were compared to determine if one was superior to the others: tutoring, individu-alized support, and distribution of academic material. The results of subgroup analysis failed to detect any differences between effect sizes, most likely due to low statistical power. Thus, the main trends were discussed. Tutoring, as the most rigorously evaluated intervention, appeared to outperform other types of intervention strategies, especially in respect to mathematical skills, where the results remained robust despite potential methodological bias. However, it is essential to consider significant limitations when interpreting these results. Implications for practice and research are discussed.
AN  - WOS:001140365800001
AU  - Goulet,
AU  - J.
AU  - Maltais,
AU  - C.
AU  - Archambault,
AU  - I.
AU  - No&euml;l,
AU  - V.
AU  - Gu&eacute;riton,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.childyouth.2023.107388
L1  - internal-pdf://4168120463/1-s2.0-S0190740923005844-main.cleaned.pdf
PY  - 2024
SP  - 15
T2  - Children and Youth Services Review
TI  - Supporting academic achievement of children in out-of-home care through effective interventions: results of a systematic review and meta-analyses
UR  - &lt;Go to ISI&gt;://WOS:001140365800001
UR  - https://www.sciencedirect.com/science/article/pii/S0190740923005844?via%3Dihub
VL  - 156
ER  -
TY  - JOUR
AB  - Introduction
Parenting interventions have the potential to become effective strategies for improving the developmental trajectories of infants and children born prematurely. However, the effectiveness of parenting interventions is not well understood.

Methods
A literature search was conducted in five databases. A total of 24 studies involving 3,636 participants were included for review.

Results
The results showed a significant effect in cognition, language, motor development, and behavioral problems of children born prematurely. Parenting stress, anxiety, and interactive behaviors showed significant effect size.

Discussion
This review focuses on interventions that employ scaffolding parenting strategies to enhance the development of children born prematurely. Efforts should continue to empower parents through effective and sustainable parenting interventions to improve the quality of life of preterm children.
AN  - 39023458
AU  - Oh,
AU  - W.
AU  - O.
AU  - Heo,
AU  - Y.
AU  - J.
DB  - Juli 2024.enl
DO  - /10.1016/j.pedhc.2024.06.005
L1  - internal-pdf://2571975763/1-s2.0-S0891524524001482-main.pdf
PY  - 2024
SP  - 17
T2  - Journal of Pediatric Health Care
TI  - Early Parenting Interventions to Enhance Development in Infants and Children Born Prematurely: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.pedhc.2024.06.005
VL  - 17
ER  -
TY  - JOUR
AB  - **Background**
Cognitive-behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) are recommended treatments for pediatric obsessive-compulsive disorder (OCD), but their relative efficacy and acceptability have not been comprehensively examined. Further, it remains unclear whether the efficacy of in-person CBT is conserved when delivered in other formats, such as over telephone/webcam or as Internet-delivered CBT (ICBT).

**Methods**
PubMed, PsycINFO, trial registries, and previous systematic reviews were searched for randomized controlled trials (RCTs) comparing CBT (in-person, webcam/telephone-delivered, or ICBT) or SRIs with control conditions or each other. Network meta-analyses were conducted to examine efficacy (post-treatment Children&#039;s Yale-Brown Obsessive Compulsive Scale) and acceptability (treatment discontinuation). Confidence in effect estimates was evaluated with CINeMA (Confidence in Network Meta-Analysis).

**Results**
Thirty eligible RCTs and 35 contrasts comprising 2,057 youth with OCD were identified. In-person CBT was significantly more efficacious than ICBT, waitlist, relaxation training, and pill placebo (MD range: 3.95-11.10; CINeMA estimate of confidence: moderate) but did not differ significantly from CBT delivered via webcam/telephone (MD: 0.85 [-2.51, 4.21]; moderate), SRIs (MD: 3.07 [-0.07, 6.20]; low), or the combination of in-person CBT and SRIs (MD: -1.20 [-5.29, 2.91]; low). SRIs were significantly more efficacious than pill placebo (MD: 4.59 [2.70, 6.48]; low) and waitlist (MD: 8.03 [4.24, 11.82]; moderate). No significant differences for acceptability emerged, but confidence in estimates was low.

**Conclusions**
In-person CBT and SRIs produce clear benefits compared to waitlist and pill placebo and should be integral parts of the clinical management of pediatric OCD, with in-person CBT overall having a stronger evidence base. The combination of in-person CBT and SRIs may be most efficacious, but few studies hinder firm conclusions. The efficacy of CBT appears conserved when delivered via webcam/telephone, while more trials evaluating ICBT are needed.
AN  - WOS:001135453200001
AU  - Cervin,
AU  - M.
AU  - McGuire,
AU  - J.
AU  - F.
AU  - D&#039;Souza,
AU  - J.
AU  - M.
AU  - De
AU  - Nadai,
AU  - A.
AU  - S.
AU  - Aspvall,
AU  - K.
AU  - Goodman,
AU  - W.
AU  - K.
AU  - Andr&eacute;n,
AU  - P.
AU  - Schneider,
AU  - S.
AU  - C.
AU  - Geller,
AU  - D.
AU  - A.
AU  - Mataix-Cols,
AU  - D.
AU  - Storch,
AU  - E.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1111/jcpp.13934
L1  - internal-pdf://0491745658/Cervin-2024-Efficacy and acceptability of cogn.pdf
PY  - 2024
SP  - 16
T2  - Journal of Child Psychology and Psychiatry
TI  - Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001135453200001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.13934?download=true
ER  -
TY  - JOUR
AB  - Objective: Aerobic exercise (AE) interventions are beginning to be used as an emerging adjunctive treatment modality in the treatment of children with Attention Deficit Hyperactivity Disorder (ADHD). However, to date, there is no substantial evidence to support the improved effects of aerobic exercise intervention in children with ADHD aged 6&ndash;12&thinsp;years. This study aims to investigate the effect of aerobic exercise therapy on executive function in children with attention deficit hyperactivity disorder aged 6&ndash;12&thinsp;years.

Method: We conducted a systematic review and meta-analysis using PubMed and Web of Science. The cut-off date was June 1, 2023. The aim was to assess the impact of aerobic exercise interventions on children with ADHD and all randomized controlled trials eligible for aerobic exercise interventions for children with ADHD were included. Nine randomized controlled trials were screened for eligibility for systematic evaluation, and the nine studies were assessed for risk of bias using the PEDro score and the GRADE Quality of Evidence Evaluation System for quality grading of outcome indicators. After testing for heterogeneity, a random-effects model was selected for analysis. Finally, meta-analyses and regression analyses were performed on the core functions (inhibitory control, cognitive flexibility, and working memory) and subgroups of the nine studies on executive function using Revman 5.4 and Stata 16.0.

Results: The risk of bias evaluation showed a mean PEDro score of 7.78, and of the nine studies, two were rated as having excellent methodological quality, while the remaining seven had a good level of evidence, and the GRADE evidence evaluation showed that the outcome indicators were all of moderate quality. Inhibitory control [SMD&thinsp;=&thinsp;0.83,95% CI (0.37&ndash;1.29), Z&thinsp;=&thinsp;3.51, p =&thinsp;0.0005], cognitive flexibility [SMD&thinsp;=&thinsp;0.65,95% CI (0.37&ndash;0.93), Z&thinsp;=&thinsp;4.58, p &lt;&thinsp;0.00001], and working memory [SMD&thinsp;=&thinsp;0.48,95% CI (0.02&ndash;0.95), Z&thinsp;=&thinsp;2.03, p =&thinsp;0.04] were statistically significant, with effect sizes of moderate or higher; furthermore, in subgroup analyses type of intervention, duration, intensity, and medication use had different effects on inhibitory control and cognitive flexibility, and the combined IC, CF statistic found that a single category of aerobic exercise ( &beta; =&thinsp;0.867, p &lt;&thinsp;0.001), moderate intensity ( &beta; =&thinsp;0.928, p &lt;&thinsp;0.001), 6&ndash;12&thinsp;weeks (&beta;&thinsp;=&thinsp;0.804, p &lt;&thinsp;0.001), 60-90&thinsp;min ( &beta; =&thinsp;0.894, p &lt;&thinsp;0.001), and the use of medication ( &beta; =&thinsp;1.202, p =&thinsp;0.002) were better for overall improvement in EF.

Conclusion: Aerobic exercise therapy significantly improved executive functioning in children with ADHD, showing above moderate effect sizes especially in inhibitory control, cognitive flexibility, and working memory. Aerobic exercise therapy can be used as a reference in improving executive function in children with ADHD, but given the limitations of this study, it should be used with caution when applied in clinical settings.
AN  - WOS:001260072000001
AU  - Yang,
AU  - G.
AU  - Liu,
AU  - Q.
AU  - Wang,
AU  - W.
AU  - Liu,
AU  - W.
AU  - Li,
AU  - J.
AU  - F.
DB  - Juli 2024.enl
DO  - 10.3389/fpsyg.2024.1376354
L1  - internal-pdf://0747911884/Yang-2024-Effect of aerobic exercise on the im.pdf
PY  - 2024
SP  - 15
T2  - Frontiers in Psychology
TI  - Effect of aerobic exercise on the improvement of executive function in children with attention deficit hyperactivity disorder: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001260072000001
UR  - https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2024.1376354/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - This study aims to investigate the impact of frilufts-therapy (Nordic inspired therapeutic interventions in nature) on adolescents&#039; mental health through a systematic literature review following PRISMA 2020 guidelines. Inclusion criteria encompassed peer-reviewed intervention studies in English, Danish, or Norwegian, quantitatively evaluated with pre- and post-measurements on outcomes pertaining to salutogenesis. Papers published between 2010-2021 were selected from PubMed and PsycInfo in November 2021. Risk of bias was assessed using Cochrane RoB 2, ROBINS-I, and NIH tools synthesized into a six-domain assessment. Ten papers evaluating 12 studies (1711 adolescents) were selected. Meta-analysis of effect estimates on controlled studies (7) revealed a medium to large effect (ES = 0.70; CI = 0.41-0.98) favouring frilufts-therapy. Meta-analysis without control (11 studies) showed a medium effect (ES = 0.52; CI = 0.34-0.70) favouring post-test measurements. This support evidence that frilufts-therapy can improve the mental health of adolescents, but caution is advised due to potential study limitations, necessitating further research.
AN  - WOS:001220490700001
AU  - Lousen,
AU  - I.
AU  - Andkjær,
AU  - S.
DB  - Juni 24.enl
DO  - 10.1080/14729679.2024.2335554
L1  - internal-pdf://0774205338/Lousen-2024-Frilufts-therapy can improve adole.pdf
PY  - 2024
SP  - 19
T2  - Journal of Adventure Education and Outdoor Learning
TI  - Frilufts-therapy can improve adolescents&#039; mental health. A systematic review and meta-analysis of intervention studies
UR  - &lt;Go to ISI&gt;://WOS:001220490700001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/14729679.2024.2335554
ER  -
TY  - JOUR
AB  - Purpose: Executive functioning is said to be fundamental to human cognition and achievement. This meta-analysis aimed to establish what effect - if any - yoga delivered in school-settings has upon the executive functioning skills of children between three and seven years of age. 

Procedure: Databases screened were PubMed Central, Web of Science, CINAHL, Scopus, and PsycARTICLES. Studies involving a yoga-based intervention alongside a control group, and age-appropriate measures of executive functioning were included. In total, seven studies, involving 1080 participants, met the inclusion criteria. 

Findings: Meta-analysis of all seven studies demonstrated a significant (p &lt; 0.001) small positive weighted average effect size (Cohen&#039;s d) of 0.24 [95% CI 0.10, 0.39], evidencing that yoga may improve the executive functioning skills of children between three and seven years of age. Sub-group meta-analyses to examine the different domains of executive functioning (working memory, inhibitory control, and cognitive flexibility) revealed a significant (p = 0.007) small positive effect size (Cohen&#039;s d) of 0.41 [95% CI 0.11, 0.70] for working memory, and a significant (p = 0.033) marginal positive effect size (Cohen&#039;s d) of 0.18 [95% CI 0.01, 0.34] for inhibitory control. However, there were insufficient data for a sub-group meta-analysis of cognitive flexibility. 

Conclusions: Results are discussed in the context of &#039;hot&#039; and &#039;cold&#039; executive functioning skills. Study limitations are considered, and it is acknowledged that further high-quality research is needed into the effect(s) of school-based yoga on executive functioning within this population before definitive conclusions can be drawn.
AN  - WOS:001343403000001
AU  - Wilkin,
AU  - K.
AU  - Allen-Baker,
AU  - G.
AU  - Thornton,
AU  - C.
DB  - November 2024.enl
DO  - 10.1016/j.mhpa.2024.100643
L1  - internal-pdf://3179316231/1-s2.0-S1755296624000693-main.pdf
internal-pdf://2391442439/The effects of school-based yoga on the execut.pdf
PY  - 2024
SP  - 11
T2  - Mental Health and Physical Activity
TI  - The effects of school-based yoga on the executive functioning skills of children between three and seven years of age. A meta-analysis of existing research
UR  - &lt;Go to ISI&gt;://WOS:001343403000001
UR  - https://www.sciencedirect.com/science/article/pii/S1755296624000693?pes=vor&amp;utm_source=clarivate&amp;getft_integrator=clarivate
VL  - 27
ER  -
TY  - JOUR
AB  - Background
and aims: Common Mental Disorders (CMD) emerged as a substantial global burden, emphasizing the necessity of investigating effective treatment modalities, particularly in telemedicine. This umbrella review and meta-meta-analysis systematically evaluated telemedicine&#039;s effectiveness for CMD.

Methods
Key databases (PsycINFO, PubMed, EMBASE, Cochrane Library) were searched for telemedicine interventions targeting CMD, including depression and anxiety. The interventions included video conferencing, mobile applications, remote monitoring, and other communication technologies. Multiple subgroup analyses were conducted based on diverse outcomes, populations, and severity levels to gauge real-world effectiveness. The study, registered on PROSPERO (CRD42023452382), began in October 2022, with analysis from June to August 2023 and an update in April 2024.

Results
The umbrella review included 191 systematic reviews, and the meta-meta-analysis incorporated 72 meta-analyses, assessed for quality using the AMSTAR-2 tool. Results showed significant differences in depression outcomes between telemedicine and positive controls (SMD = &minus;0.29) and blank controls (SMD = &minus;0.53), both P &lt; 0.001. For anxiety, effects were also notable (SMD = &minus;0.26 for positive controls, SMD = &minus;0.68 for blank controls, both P &lt; 0.001). Telemedicine had no significant impact on adolescents but significantly improved depression (SMD = &minus;0.49, P &lt; 0.001) and anxiety (SMD = &minus;0.37, P &lt; 0.001) in adults. Across mild and severe CMD cases, telemedicine consistently demonstrated positive effects with no subgroup variations (both SMD = &minus;0.47, P &lt; 0.001).

Conclusions
In summary, telemedicine interventions showcase effectiveness comparable to traditional face-to-face methods in treating CMD. Furthermore, compared to blank controls, telemedicine exhibits significant therapeutic effectiveness.
AN  - WOS:001259455300001
AU  - Chen,
AU  - J.
AU  - Li,
AU  - C.
AU  - An,
AU  - K.
AU  - Dong,
AU  - X.
AU  - T.
AU  - Liu,
AU  - J.
AU  - Y.
AU  - Wu,
AU  - H.
DB  - Juli 2024.enl
DO  - 10.1016/j.chb.2024.108325
L1  - internal-pdf://3189259628/1-s2.0-S0747563224001936-main.cleaned.pdf
PY  - 2024
SP  - 19
T2  - Computers in Human Behavior
TI  - Effectiveness of telemedicine on common mental disorders: An umbrella review and meta-meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001259455300001
VL  - 159
ER  -
TY  - JOUR
AB  - Insomnia is common in adolescents with associated negative health consequences. This systematic review and meta-analysis assessed the effect of cognitive behavioural therapy for insomnia interventions on insomnia symptoms and subjective sleep quality in adolescents aged 10-19 years. Key electronic databases, including CINAHL, Embase, MEDLINE, PsycINFO and Scopus, were systematically searched from inception to October 2024, and five randomised controlled trials met inclusion criteria for qualitative synthesis. Four randomised controlled trials, examining a total of 527 participants, were included in the meta-analysis. One randomised controlled trial employing a hybrid cluster design was excluded in quantitative analyses due to the number of clusters and sizes not reported. Cognitive behavioural therapy for insomnia delivered to adolescents with insomnia improved subjective sleep quality and insomnia symptoms, with effect sizes (Hedge&#039;s g) of 0.4 and 1.04, respectively. Our findings provide support for the efficacy of cognitive behavioural therapy for insomnia in the treatment of adolescents with insomnia regardless of delivery modality. Further high-quality randomised controlled trials are required to strengthen our findings and understand how best to deliver cognitive behavioural therapy for insomnia to adolescents.
AN  - 39680961
AU  - Galgut,
AU  - Y.
AU  - Hoyos,
AU  - C.
AU  - Kempler,
AU  - L.
AU  - Aji,
AU  - M.
AU  - Grunstein,
AU  - R.
AU  - R.
AU  - Gordon,
AU  - C.
AU  - J.
AU  - Bartlett,
AU  - D.
AU  - J.
DB  - Desember 2024.enl
DO  - /10.1111/jsr.14442
L1  - internal-pdf://1070530870/Journal of Sleep Research - 2024 - Galgut - Co.pdf
PY  - 2024
SP  - e14442
T2  - Journal of Sleep Research
TI  - Cognitive and behavioural therapy for insomnia in the treatment of adolescent insomnia: A systematic review and meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1111%2fjsr.14442
ER  -
TY  - JOUR
AB  - Objective: Early-onset psychosis (EOP) refers to the development of psychosis before the age of 18 years. We aimed to summarize, for the fi rst time, the meta-analytical evidence in the fi eld of this vulnerable population and to provide evidence-based recommendations. Method: We performed a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) - compliant, pre-registered (PROSPERO: CRD42022350868) systematic review of several databases and registers to identify meta-analyses of studies conducted in EOP individuals to conduct an umbrella review. Literature search, screening, data extraction, and quality assessment were carried out independently. Results were narratively reported, clustered across core domains. Quality assessment was performed with the Assessment of Multiple Systematic Reviews - 2 (AMSTAR-2) tool. Results: A total of 30 meta-analyses were included (373 individual studies, 25,983 participants, mean age 15.1 years, 38.3% female). Individuals with EOP showed more cognitive impairments compared with controls and individuals with adult/late-onset psychosis. Abnormalities were observed metaanalytically in neuroimaging markers but not in oxidative stress and in fl ammatory response markers. In all, 60.1% of EOP individuals had a poor prognosis. Clozapine was the antipsychotic with the highest eff i cacy for overall, positive, and negative symptoms. Tolerance to medication varied among the evaluated antipsychotics. The risk of discontinuation of antipsychotics for any reason or side effects was low or equal compared to placebo. Conclusion: EOP is associated with cognitive impairment, involuntary admissions, and poor prognosis. Antipsychotics can be eff i cacious in EOP, but tolerability and safety need to be taken into consideration. Clozapine should be considered in EOP individuals who are resistant to 2 non-clozapine antipsychotics. Further meta-analytical research is needed on response to psychological interventions and other prognostic factors. Plain language summary: This umbrella review summarized the meta-analytical knowledge from 30 meta-analyses on early-onset psychosis. Earlyonset psychosis refers to the development of psychosis before the age of 18 years and is associated with cognitive impairment, hospitalization, and poor prognosis. Individuals with early-onset psychosis show more cognitive impairments and abnormalities compared with controls. Clozapine was the antipsychotic with the highest eff i cacy for positive, negative, and overall symptoms and should be considered in individuals with early-onset psychosis.
AN  - WOS:001262287100001
AU  - de
AU  - Pablo,
AU  - G.
AU  - S.
AU  - Rodriguez,
AU  - V.
AU  - Besana,
AU  - F.
AU  - Civardi,
AU  - S.
AU  - C.
AU  - Arienti,
AU  - V.
AU  - Garceo,
AU  - L.
AU  - M.
AU  - Andr&eacute;s-Camaz&oacute;n,
AU  - P.
AU  - Catalan,
AU  - A.
AU  - Rogdaki,
AU  - M.
AU  - Abbott,
AU  - C.
AU  - Kyriakopoulos,
AU  - M.
AU  - Fusar-Poli,
AU  - P.
AU  - Correll,
AU  - C.
AU  - U.
AU  - Arango,
AU  - C.
DB  - August 2024.enl
DO  - 10.1016/j.jaac.2023.10.016
L1  - internal-pdf://2744345032/1-s2.0-S0890856724000066-main.cleaned.pdf
PY  - 2024
SP  - 684-697
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Umbrella Review: Atlas of the Meta-Analytical Evidence of Early-Onset Psychosis
UR  - &lt;Go to ISI&gt;://WOS:001262287100001
VL  - 63
ER  -
TY  - JOUR
AB  - Background: Recent researches highlighted the significant role of the gut-brain axis and gut microbiota in autism spectrum disorder (ASD), a neurobehavioral developmental disorder characterized by a variety of neuropsychiatric and gastrointestinal symptoms, suggesting that alterations in the gut microbiota may correlate with the severity of ASD symptoms. Therefore, this study was designed to conduct a comprehensive systematic review and meta-analysis of the effectiveness of probiotic interventions in ameliorating behavioral symptoms in individuals with ASD. 

Methods: This study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. A comprehensive literature search was performed across multiple databases including the Cochrane Library, PubMed, Web of Science, and Google Scholar up until June 2024. Inclusion criteria encompassed published randomized clinical trials (RCTs), focusing on probiotic interventions and evaluating outcomes related to ASD behavior symptoms. The study utilized Cochrane&#039;s Risk of Bias 2 for bias assessment and applied random effect models with inverse variance method for statistical analysis, also addressing publication bias and conducting subgroup analyses through Begg&#039;s and Egger&#039;s tests to explore the effects of various factors on the outcomes.

Results: Our meta-analysis, which looked at eight studies with a total of 318 samples from ASD patients aged 1.5-20 years, showed that the probiotic intervention group had significantly better behavioral symptoms compared to the control group. This was shown by a pooled standardized mean difference (SMD) of -0.38 (95% CI: 0.58 to -0.18, p &lt; 0.01). Subgroup analyses revealed significant findings across a variety of factors: studies conducted in the European region showed a notable improvement with an SMD of -0.44 (95%CI: 0.72 to -0.15); interventions lasting longer than three months exhibited a significant improvement with an SMD of -0.43 (95% CI: 0.65 to -0.21); and studies focusing on both participants under and greater than 10 years found significant benefits with an SMDs of -0.37 and -0.40, respectively (95%CI: 0.65 to -0.09, and 95%CI: 0.69 to -0.11, respectively). Moreover, both multi-strain probiotics and single-strain interventions showed an overall significant improvement with a SMD of -0.53 (95%CI: 0.85 to -0.22) and -0.28 (95%CI: 0.54 to -0.02), respectively. Also, the analysis confirmed the low likelihood of publication bias and the robustness of these findings. 

Conclusion: Our study highlighted the significant improvement in ASD behavioral symptoms through probiotic supplementation. The need for personalized treatment approaches and further research to confirm efficacy and safety of probiotics in ASD management is emphasized.
AN  - WOS:001314893700001
AU  - Soleimanpour,
AU  - S.
AU  - Abavisani,
AU  - M.
AU  - Khoshrou,
AU  - A.
AU  - Sahebkar,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1016/j.jpsychires.2024.09.009
L1  - internal-pdf://2901739967/Soleimanpour_2024.pdf
PY  - 2024
SP  - 92-104
T2  - Journal of Psychiatric Research
TI  - Probiotics for autism spectrum disorder: An updated systematic review and meta-analysis of effects on symptoms
UR  - &lt;Go to ISI&gt;://WOS:001314893700001
UR  - https://www.sciencedirect.com/science/article/pii/S0022395624005314?via%3Dihub
VL  - 179
ER  -
TY  - JOUR
AB  - CONTEXT: Most youths who die by suicide have interfaced with a medical system in the year preceding their death, placing outpatient medical settings on the front lines for identification, assessment, and intervention. 

OBJECTIVE: Review and consolidate the available literature on suicide risk screening and brief intervention with youths in outpatient medical settings and examine common outcomes. 

DATA SOURCES: The literature search looked at PubMed, OVID, CINAHL, ERIC, and PsychInfo databases. 

STUDY SELECTION: Interventions delivered in outpatient medical settings assessing and mitigating suicide risk for youths (ages 10-24). Designs included randomized controlled trials, prospective and retrospective cohort studies, and case studies. 

DATA EXTRACTION: Authors extracted data on rates of referral to behavioral health services, initiation/adjustment of medication, follow-up in setting of assessment, suicidal ideation at follow-up, and suicide attempts and/or crisis services visited within 1 year of initial assessment. 

RESULTS: There was no significant difference in subsequent suicide attempts between intervention and control groups. Analysis on subsequent crisis service could not be performed due to lack of qualifying data. Key secondary findings were decreased immediate psychiatric hospitalizations and increased mental health service use, along with mild improvement in subsequent depressive symptoms. 

LIMITATIONS: The review was limited by the small number of studies meeting inclusion criteria, as well as a heterogeneity of study designs and risk of bias across studies. 

CONCLUSIONS: Brief suicide interventions for youth in outpatient medical settings can increase identification of risk, increase access to behavioral health services, and for crisis interventions, can limit psychiatric hospitalizations.
AN  - 38356411
AU  - Pitts,
AU  - B.
AU  - H.
AU  - Doyle,
AU  - R.
AU  - Wood,
AU  - L.
AU  - Dar,
AU  - R.
AU  - De
AU  - Jesus
AU  - Ayala,
AU  - S.
AU  - Sharma,
AU  - T.
AU  - St
AU  - Pierre,
AU  - M.
AU  - Anthony,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1542/peds.2023-061881
L1  - internal-pdf://1620721359/Pitts-2024-Brief Interventions for Suicidal Yo.pdf
PY  - 2024
SP  - 15
T2  - Pediatrics
TI  - Brief Interventions for Suicidal Youths in Medical Settings: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38356411
UR  - https://watermark.silverchair.com/peds.2023-061881.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA04wggNKBgkqhkiG9w0BBwagggM7MIIDNwIBADCCAzAGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMCkJuFCFK77tOCDBYAgEQgIIDAbnilNyJbrnKWSJegLE3pMpI_7TPYYZpM-Z7eXC76x3IIVwJV9nH7A_MaFyAAHLUgBEl7jG3ehi-hA7sXJWaavtRlzXpmGkPGQ-OO9GG9raWdfDnaqoxOXvshy3BaAc5i5-if6339ah-t1aUVtN1gWgOzvDCpVjTZBO9ewI7V8Zwp3ZjDh8Y8BrFZetJanJmUEP-ahYRjG6A3oZwuCITe1vL5qODrCtYfYjCyK7dF-em7SSAQOUwcRoInn_OaCNb8kDA204q-TAcJbI3IM0vGxpLsy1aekQDO-vIDQ-NkOeo0YWEtWtJe0wvZhWqZQD4EUeTty4b2fPHnG39XVT_lIDBhWIcDbgJ3Ryz-9cVuzSlUhsmhepfcgrdExm2JudFbFqYt_4FwUpzABITdUscygL8Mm97QpY8gwudw7hwfJ1Tx8eFFnb3ZeQM1VTnlqljR7xmGzSuQ_OgTIKxhwjqFtqxxspjtdd4Wt4eJjlb8rwlzXwjvNxvFmw_xbkVNYtGBh4Rr1HQsvUzQjsBIytOZNAXZvHor3b6PLeh7smHXUhWMKYNyP4mI3uBBg7QoP5MOW5ZhvA8_Yt85zsEWHS8V8zSE7WQqUY5D_XXI3CtbZXZuFBGB4TaKHP9DUTs31HAp2RdluhKoJsK4yw2yXRbvYNjLkwNFZZMoX2DCJ8OE_Scg6ZxUWwvG7a66ybBQx1eNLekfSr15gsUgHTNo_2QFnjkKmiHWTyZNuAtbvYjXnd2KqgTBdqpTJnjUh0iVkloClQ_mA5d1YOMjOl5vhR0ubml1DwjqcCMFNIF4VlFt3HvRqcgucLDTzhZdt0aRp9quiS2VGZ3XFnEAK36GPaqeEiSAuRHf7sGta7SR30UfX9JsrrX-dTp7OBVJgP-lltzCnXgMudzerBnHDbjHXIUrtSZWjvq6FcBuH1k2vsWBSuqwnEUHGd7GoEhpRFzretB55BKadZrUyfiWBF-2TBNXYh4egirBnTuV9C8rEW93ZNEXRnW1VKQWG9Yj0dXAZMAVx0
VL  - 15
ER  -
TY  - JOUR
AB  - OBJECTIVE: This document is a meta-analysis of randomized controlled trials that evaluated the effect of cognitive training interventions on attention deficit and hyperactivity disorder (ADHD) symptoms. 

METHODS: A systematic literature search was conducted using databases such as PubMed, Web of Science, and Embase from the inception of each database to April 28, 2022. Data were analyzed using Stata 15 software. The risk of bias assessment was conducted using five domains from the Cochrane Collaborations tool. 

RESULTS: A total of 10 studies with 446 children with ADHD were included. The results showed that cognitive training was effective in improving attention symptoms [SMD= -0.78 (95% CI: -1.46, -0.1)] and executive function [SMD = -0.3 (95% CI: -0.56, -0.05)] in children with ADHD compared to controls. No significant difference in the degree of improvement in hyperactivity/impulsivity with cognitive training compared to the control group [SMD = -0.65 (95% CI: -1.35, 0.05)]. In addition, subgroup analyses also found that cognitive training significantly improved attention in children with ADHD &lt;10 years of age [SMD = -1.3 (95% CI: -2.58, -0.02)] and children with ADHD with length of training &gt;30 days [SMD = -0.94 (95% CI: -1.81, -0.07)] compared to controls. 

CONCLUSION: This meta-analysis found that the beneficial effects of cognitive training on attention (particularly for children with ADHD &lt;10 years old and &gt;30 days of training) and executive function in children with ADHD, but not on hyperactivity/impulsivity.
AN  - 38261550
AU  - Zou,
AU  - X.
AU  - Yu,
AU  - F.
AU  - Huang,
AU  - Q.
AU  - Huang,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/21622965.2024.2305874
L1  - internal-pdf://2436208638/Zou-2024-The effect of cognitive training on c.pdf
PY  - 2024
SP  - 1-10
T2  - Applied Neuropsychology
TI  - The effect of cognitive training on children with attention deficit and hyperactivity disorder: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38261550
UR  - https://www.tandfonline.com/doi/pdf/10.1080/21622965.2024.2305874
VL  - Child.
ER  -
TY  - JOUR
AB  - To investigate the effect of psychosocial interventions on emotion regulation outcomes in children and youth (0-23 years). We conducted a meta-analysis using a three-level modeling approach extracting multiple effect-sizes from experimental and quasi-experimental studies. We included 40 interventions from 35 publications involving 3,891 participants and extracted 258 posttreatment effect sizes. Analyses were performed to assess intervention effects on emotion regulation, moderating effects of inclusion of acceptance focus and other potential moderators. Additionally, we examined intervention effects on mental health outcomes. Interventions showed a significant small-to-medium effect on emotion regulation (d = 0.37, 95% CI [0.22, 0.51], p &lt; .001). Similar effects on were found regardless of acceptance-focus. Interventions significantly associated with a higher level of effect (p &lt;= 0.045) included ACT, DBT, CBT and behavior parent training interventions. Significant small-to-medium effects were found for mental health outcomes (d = 0.39, 95% CI [0.25, 0.53], p &lt; .001), with a correlation of .56 between overall outcomes across domains. Meta-regression results indicated that psychosocial interventions are moderately effective in improving emotion regulation, with no significant difference in inclusion of acceptance-focus. Findings suggest that emotion regulation is a transdiagnostic process that may inform the development of more beneficial interventions.
AN  - 38717667
AU  - Espenes,
AU  - K.
AU  - Tormoen,
AU  - A.
AU  - J.
AU  - Rognstad,
AU  - K.
AU  - Nilsen,
AU  - K.
AU  - H.
AU  - Waaler,
AU  - P.
AU  - M.
AU  - Wentzel-Larsen,
AU  - T.
AU  - Kjobli,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1007/s10488-024-01373-3
L1  - internal-pdf://0562519174/Espenes-2024-Effect of Psychosocial Interventi.pdf
PY  - 2024
SP  - 08
T2  - Administration &amp; Policy in Mental Health
TI  - Effect of Psychosocial Interventions on Children and Youth Emotion Regulation: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs10488-024-01373-3
UR  - https://link.springer.com/content/pdf/10.1007/s10488-024-01373-3.pdf
VL  - 08
ER  -
TY  - JOUR
AB  - The Multiphase Optimization Strategy (MOST) is a three-phase iterative framework that could accelerate the development of behavioral interventions. This systematic review and meta-analysis was conducted within the MOST preparation phase and aimed to classify components included in pediatric sleep duration interventions, using the Behavior Change Technique (BCT) Taxonomy. Across 37 interventions, 46 out of 93 BCTs have been used, with an average of 8 techniques used per study. The most common BCTs used were instruction on how to perform the behavior (N = 29; code 4.1), practical social support (N = 22; code: 3.2), and behavioral practice/rehearsal (N = 22; code: 8.1). A latent class analysis identified two classes of interventions, distinguished by the presence of BCTs falling within the following behavior change groups: shaping knowledge, natural consequences, comparison of behavior, and repetition and substitution. Our meta-analysis revealed that interventions belonging to the latent class with these behavior change groups (N = 15) had a pooled positive intervention effect of 14 min (95 % CI: 8-21) versus 8 min (95 % CI: 1-15) for interventions without these behavior change groups (N = 19). This systematic review and meta-analysis will enhance the development of sleep promotion interventions and guide the selection of candidate intervention components for future optimization and randomized control trials.
AN  - 39216182
AU  - Decker,
AU  - J.
AU  - E.
AU  - Morales,
AU  - K.
AU  - H.
AU  - Fair,
AU  - M.
AU  - A.
AU  - Vallecorsa,
AU  - G.
AU  - Subramanyam,
AU  - S.
AU  - Fiks,
AU  - A.
AU  - G.
AU  - Mayne,
AU  - S.
AU  - Williamson,
AU  - A.
AU  - A.
AU  - Mitchell,
AU  - J.
AU  - A.
DB  - November 2024.enl
DO  - /10.1016/j.smrv.2024.101995
L1  - internal-pdf://3778377417/Classifying intervention components used in sl.pdf
PY  - 2024
SP  - 101995
T2  - Sleep Medicine Reviews
TI  - Classifying intervention components used in sleep duration interventions for children: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.1016%2fj.smrv.2024.101995
UR  - https://www.sciencedirect.com/science/article/pii/S1087079224000996?via%3Dihub
VL  - 78
ER  -
TY  - JOUR
AB  - IMPORTANCE: Individuals with autism spectrum disorder (ASD) and intellectual disability often experience persistent challenges related to aggressive behaviour and agitation, highlighting the critical need for evidence-based pharmacological interventions among other strategies. Despite previous network meta-analyses (NMAs), the rapidly evolving landscape of treatment options necessitates ongoing and updated assessments. 

OBJECTIVE: To evaluate the efficacy and tolerability of various pharmacotherapies in managing agitation in children and adults with ASD or intellectual disabilities (ID). 

METHODS: Employing a systematic review and network meta-analysis methodology, we conducted an exhaustive search across multiple databases for double-blind, randomized controlled trials focusing on pharmacotherapies targeting agitation in these neurodevelopmental disorders. Adhering to Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines, our assessment of study quality utilized the Cochrane Risk of Bias Tool to ensure methodological rigour and accuracy in data synthesis. Primary outcomes encompassed measures of reduced agitation, as indicated by treatment response on standardized agitation scales, alongside dropout rates, providing a comprehensive overview of treatment efficacy and tolerability. 

RESULTS: Our analysis included data from 38 eligible trials, involving 2503 participants across both pediatric and adult populations. Key pharmacological interventions, such as arbaclofen, risperidone plus buspirone, omega-3 fatty acids, risperidone plus palmitoylethanolamide, aripiprazole and risperidone, demonstrated significant efficacy in reducing agitation compared to placebo. Importantly, these treatments were generally well-tolerated, with no significant increase in all-cause dropouts compared to placebo, highlighting their suitability for clinical use in managing agitation in individuals with ASD or ID. 

CONCLUSIONS: This study underscores the efficacy and tolerability of several pharmacotherapies in managing agitation among children and adults with ASD or ID. Our findings provide robust evidence that specific treatments, such as arbaclofen, risperidone plus buspirone and omega-3 fatty acids, are both effective and well-tolerated, offering valuable therapeutic options for clinicians. The study emphasizes the need for ongoing research to ensure that treatment strategies remain aligned with the evolving clinical landscape, ultimately improving patient outcomes in this challenging population.
AN  - 39690490
AU  - Bahji,
AU  - A.
AU  - Forth,
AU  - E.
AU  - Nasar,
AU  - A.
AU  - Waqas,
AU  - A.
AU  - Hawken,
AU  - E.
AU  - R.
AU  - Ayub,
AU  - M.
DB  - Desember 2024.enl
DO  - /10.1177/02698811241303654
L1  - internal-pdf://3099656518/bahji-et-al-2024-navigating-agitation-in-neuro.pdf
PY  - 2024
SP  - 2698811241303654
T2  - Journal of Psychopharmacology
TI  - Navigating agitation in neurodevelopmental disorders: A comparative study of pharmacotherapies via network meta-analysis in children and adults with autism spectrum disorder or intellectual disabilities
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1177%2f02698811241303654
UR  - https://journals.sagepub.com/doi/10.1177/02698811241303654
ER  -
TY  - JOUR
AB  - **Huvudbudskap**
Forskning visar att det finns insatser som involverar socialtj&auml;nst eller motsvarande som kan minska skjutvapenvåld, medlemskap i g&auml;ng och fortsatt kriminalitet bland unga personer.

**Slutsatser**
Efter att ha gått igenom den samlade vetenskapliga litteraturen har SBU dragit f&ouml;ljande slutsatser:

F&auml;rdighetstr&auml;ning i skolan f&ouml;r elever på mellanstadiet (t.ex. konfliktl&ouml;sning) kan f&ouml;rebygga medlemskap i g&auml;ng och b&auml;rande av vapen.
Insatser av typen fokuserad avskr&auml;ckning1 bland g&auml;ngkriminella minskar skjutvapenvåld med en fj&auml;rdedel, &ouml;ver en tid av i genomsnitt cirka tre år.
Psykosociala insatser till g&auml;ngkriminella under frivård (t.ex. missbruksbehandling, st&ouml;d att s&ouml;ka arbete) kan minska fortsatt kriminalitet med knappt h&auml;lften upp till ett år efter avslutad insats.
Insatser mot &ouml;ppna drogmarknader i form av fokuserad avskr&auml;ckning kan minska narkotikabrottslighet med cirka en tredjedel, &ouml;ver en tid av i genomsnitt ett och ett halvt år.
Insatser med os&auml;ker effektivitet eller os&auml;kra risker i form av stigmatisering och urholkat f&ouml;rtroende f&ouml;r viktiga samh&auml;llsfunktioner beh&ouml;ver utv&auml;rderas.
1. F&ouml;r att minska våld riktar samh&auml;llet sina resurser mot de mest våldsdrivande individerna och de g&auml;ng de tillh&ouml;r. De informeras om att våldet måste upph&ouml;ra, vilka konsekvenser fortsatt våld kommer att ge samt erbjuder st&ouml;d till de som vill l&auml;mna det kriminella livet.

**Hur kan de viktigaste resultaten f&ouml;rstås?**
N&auml;stan alla studier &auml;r genomf&ouml;rda i USA. Det kan påverka resultatens relevans i Sverige. Det enda s&auml;kra s&auml;ttet att avg&ouml;ra om insatserna fungerar &auml;ven h&auml;r &auml;r genom att låta inf&ouml;ra och utv&auml;rdera insatserna i Sverige. I rapporten redovisas tre typer av insatser f&ouml;r att motverka g&auml;ngrelaterad kriminalitet. Universella insatser ges brett till många personer, till exempel till alla elever vid en skola. Selektiva insatser erbjuds personer med en f&ouml;rh&ouml;jd risk f&ouml;r g&auml;ngrelaterad kriminalitet. Indikerade insatser &auml;r inriktade mot g&auml;ngkriminella personer. Det kan handla om kriminalvård, insatser mot &ouml;ppna drogmarknader, och fokuserad avskr&auml;ckning. Insatserna kan vara frivilliga eller ske med tvång.

Resultaten tyder på att de indikerade insatserna &auml;r lika i flera avseenden. Framf&ouml;r allt f&ouml;rekommer samverkan mellan organisationer. Totalt f&ouml;rekommer tio olika delar, så kallade komponenter, som i varierande omfattning utg&ouml;r de indikerade insatserna. Den vanligaste komponenten &auml;r psykosocialt st&ouml;d från socialtj&auml;nst, som f&ouml;rekom i alla utom en insats. Andra vanliga komponenter &auml;r tydliga f&ouml;rv&auml;ntningar på g&auml;ngmedlemmar och tydliga sanktioner. Underlaget &auml;r f&ouml;r litet f&ouml;r mer riktade analyser om några komponenter &auml;r viktigare &auml;n andra.

**Vad handlar rapporten om?**
Det prim&auml;ra syftet &auml;r att utv&auml;rdera psykosociala insatser som ska motverka barns och ungas medlemskap i g&auml;ng, attityder till g&auml;ng och g&auml;ngrelaterad kriminalitet. Insatserna kan ges av socialtj&auml;nst eller andra relevanta akt&ouml;rer (t.ex. kriminalvård, skola, polis, civilsamh&auml;lle). Rapporten belyser också etiska aspekter som kan vara aktuella n&auml;r insatserna anv&auml;nds.

Det finns insatser d&auml;r det inte har gått att vetenskapligt bed&ouml;ma effekterna. Det g&auml;ller insatser som enbart ges på fångvårdsanstalt, familjebaserade insatser f&ouml;r antisociala tonåringar, medling, och insatser mot &ouml;ppna drogmarknader f&ouml;r att minska skjutvapenvåld.

**Vilka studier ligger till grund f&ouml;r resultaten?**
Resultatet baseras på 43 studier om psykosociala insatser till barn och unga vuxna under 30 år. Studierna har publicerats mellan år 2001 och april 2023 i vetenskapliga tidskrifter. Endast studier med en j&auml;mf&ouml;relsegrupp i form av standardbehandling har inkluderats.
AU  - SBU
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /sv/publikationer/SBU-utvarderar/psykosociala-insatser-for-att-forebygga-och-minska-gangkriminalitet-bland-barn-och-unga-vuxna/
L1  - internal-pdf://3767290347/psykosociala-insatser-for-att-forebygga-och-mi.pdf
PY  - 2024
T2  - SBU
TI  - Psykosociala insatser f&ouml;r att f&ouml;rebygga och minska g&auml;ngkriminalitet bland barn och unga vuxna
ER  -
TY  - JOUR
AB  - BACKGROUND: Vitamin D deficiency has been linked with several adverse maternal and fetal outcomes. 

OBJECTIVE: To summarize systematic reviews and meta-analyses evaluating the effects of vitamin D deficiency and of vitamin D supplementation in pregnancy on maternal and offspring health-related outcomes.

 METHODS: Prior to conducting this umbrella review, we registered the protocol in PROSPERO (CRD42022368003). We conducted searches in PubMed, Embase, and Cochrane Library for systematic reviews and meta-analyses on vitamin D in pregnancy, from database inception to October 2, 2023. All outcomes related to vitamin D in pregnancy obtained from the systematic reviews and meta-analyses were extracted. 

DATA EXTRACTION: Two reviewers independently chose studies and collected information on health outcomes. The quality of the included articles&#039; methodology was assessed using AMSTAR 2 (A Measurement Tool to Assess Systematic Reviews-2). 

RESULTS: We identified 16 eligible systematic reviews and meta-analyses, which included 250,569 women. Our results demonstrated that vitamin D deficiency in pregnancy is associated with increased risk of preterm birth, small-for gestational age/low birth weight infants, recurrent miscarriage, bacterial vaginosis and gestational diabetes mellitus. Vitamin D supplementation in pregnancy increases birth weight, and reduces the risk of maternal pre-eclampsia, miscarriage, and vitamin D deficiency, fetal or neonatal mortality, as well as attention-deficit hyperactivity disorder, and autism spectrum disorder in childhood. In women with gestational diabetes mellitus, vitamin D supplementation in pregnancy can reduce the risk of maternal hyperbilirubinemia, polyhydramnios, macrosomia, fetal distress, and neonatal hospitalization. 

CONCLUSION: Due to the association with adverse maternal and offspring health outcomes, we recommend the vitamin D status in pregnancy should be monitored, particularly in women at high risk of vitamin D deficiency. It is suggested that pregnant women take a dose of &gt;400 IU/day of vitamin D supplementation during pregnancy to prevent certain adverse outcomes.
AN  - 38816412
AU  - Chien,
AU  - M.
AU  - C.
AU  - Huang,
AU  - C.
AU  - Y.
AU  - Wang,
AU  - J.
AU  - H.
AU  - Shih,
AU  - C.
AU  - L.
AU  - Wu,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1038/s41387-024-00296-0
L1  - internal-pdf://1429036025/Chien-2024-Effects of vitamin D in pregnancy o.pdf
PY  - 2024
SP  - 35
T2  - Nutrition &amp; Diabetes
TI  - Effects of vitamin D in pregnancy on maternal and offspring health-related outcomes: An umbrella review of systematic review and meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.1038%2fs41387-024-00296-0
UR  - https://www.nature.com/articles/s41387-024-00296-0.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - BACKGROUND: We aimed at investigating the efficacies of probiotics in alleviating the core and associated symptoms of autism spectrum disorder (ASD). 

METHODS: Randomized placebo-controlled trials were identified from major electronic databases from inception to Nov 2023. The outcomes of interests including improvements in the total and associated symptoms of ASD were quantitatively expressed as effect size (ES) based on standardized mean difference (SMD) with 95% confidence interval (CI). 

RESULTS: Ten studies with 522 participants (mean age = 8.11) were included in this meta-analysis. The primary results revealed significant improvement in total symptoms in the probiotics group compared with the controls (SMD = - 0.19, p = 0.03, ten studies, n = 522) but not the core symptoms (i.e., repetitive restricted behaviors, As affiliations 3 and 5 are same, we have deleted the duplicate affiliations and renumbered accordingly. Please check and confirm.problems with social behaviors/communication). Subgroup analyses demonstrated improvement in total symptoms in probiotics users relative to their controls only in studies using multiple-strain probiotics (SMD = - 0.26, p = 0.03, five studies, n = 288) but not studies using single-strain regimens. Secondary results showed improvement in adaptation (SMD = 0.37, p = 0.03, three studies, n = 139) and an improvement trend in anxiety symptoms in the probiotics group compared with controls (SMD = - 0.29, 95% CI - 0.60 to 0.02, p = 0.07, three studies, n = 163) but failed to demonstrate greater improvement in the former regarding symptoms of irritability/aggression, hyperactivity/impulsivity, inattention, and parental stress. 

CONCLUSIONS: Our study supported probiotics use against the overall behavioral symptoms of ASD, mainly in individuals receiving multiple-strain probiotics as supplements. However, our results showed that probiotics use was only associated with improvement in adaptation and perhaps anxiety, but not core symptoms, highlighting the impact of adaptation on quality of life rather than just the core symptoms. Nevertheless, the limited number of included trials warrants further large-scale clinical investigations.
AN  - 39702309
AU  - Lee,
AU  - J.
AU  - C.
AU  - Chen,
AU  - C.
AU  - M.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Tsai,
AU  - I.
AU  - T.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Chiu,
AU  - H.
AU  - J.
AU  - Wang,
AU  - M.
AU  - Y.
AU  - Tang,
AU  - Y.
AU  - H.
AU  - Hung,
AU  - K.
AU  - C.
DB  - Desember 2024.enl
DO  - /10.1186/s13034-024-00848-3
L1  - internal-pdf://3067542065/Lee-2024-The therapeutic effects of probiotics.pdf
PY  - 2024
SP  - 161
T2  - Child &amp; Adolescent Psychiatry &amp; Mental Health [Electronic Resource]
TI  - The therapeutic effects of probiotics on core and associated behavioral symptoms of autism spectrum disorders: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.1186%2fs13034-024-00848-3
UR  - https://capmh.biomedcentral.com/counter/pdf/10.1186/s13034-024-00848-3.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - Background: A large body of research has identified the positive effects of physical activity on children with autism spectrum disorders (ASD). However, the specific benefits of different types of sports on executive functioning in children with ASD remain unclear. The aim of this study was to further analyze the effects of different sports on executive functioning in children with ASD using reticulated meta-analysis and to establish their effectiveness ranking. 

Methods: This study conducted a comprehensive online search in Web of Science, PubMed, Cochrane, Embase, and CNKI databases. It included randomized controlled trials and quasi-experimental studies, and synthesized the data using a Bayesian framework. 

Results: Several relevant studies were included. The results showed that physical activity significantly improved all three dimensions of executive functioning (inhibitory control, cognitive flexibility, and working memory) in children with ASD. The improvement in cognitive flexibility and inhibitory control both reached a medium effect size. However, the improvement in inhibitory control was better than that in cognitive flexibility, while the improvement in working memory did not reach the level of a medium effect. Mini Basketball was effective in improving inhibitory control and cognitive flexibility, but not working memory. Ping Pong was more effective in cognitive flexibility and working memory, but weaker in inhibitory control. Fixed Bicycle was less effective in all three dimensions. Among other interventions, Learning Bicycles, Animal-assisted therapy, and Exergaming performed better in cognitive flexibility. SPARK, Neiyang Gong, and Martial Arts were also effective in improving inhibitory control. However, SPARK and Fixed Bicycle were not significant in improving working memory. 

Conclusion: Physical activity as an intervention can significantly improve the executive function of children with ASD. The intervention effects of different sports on different dimensions of executive function vary. Mini Basketball was outstanding in improving inhibitory control and cognitive flexibility. Ping Pong was effective in improving cognitive flexibility and working memory. Fixed Bicycle was not effective in any dimension.
AN  - 39345918
AU  - Hou,
AU  - Y.
AU  - Wang,
AU  - Y.
AU  - Deng,
AU  - J.
AU  - Song,
AU  - X.
DB  - September 2024.enl
DO  - /10.3389/fpsyt.2024.1440123
L1  - internal-pdf://1586255720/Hou-2024-Effects of different exercise interve.pdf
PY  - 2024
SP  - 1440123
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Effects of different exercise interventions on executive function in children with autism spectrum disorder: a network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffpsyt.2024.1440123
UR  - https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1440123/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Cognitive behavioural therapy (CBT) is an efficacious intervention for child anxiety that has been translated into accessible digital formats, many of which involve parents in treatment. However, the value of parental involvement in treatment is not clearly understood. This systematic review examined characteristics of parental involvement (i.e., format and content of sessions, level of therapist guidance, and parent session compliance) in digital CBT for child anxiety (mean child age &lt;= 12 years) and their relation to child outcomes (primary disorder remission, clinician-, parent-, and child-rated anxiety, and global functioning). Systematic searches in CINAHL, Embase, ERIC, PsychINFO, PubMed, and Scopus up to 14th August 2023, and citation searching, identified 27 articles (as 23 studies) assessing 14 interventions. Two were parent-only programmes for 3-6-year-old children, with the remaining being parent-child programmes targeting older children. Parents were actively involved as coaches/collaborators, assisting their children with anxiety management and exposure, and less often as co-clients working on their own difficulties. Benefits of treatment were observed across interventions, except for one, psychoeducation-based programme. Higher remission rates were more frequently observed in interventions delivered in controlled settings, those with fewer parent-only sessions, or those incorporating more parent- or therapist-led exposure sessions. Most studies were conducted with affluent samples, limiting generalisability, and several received a high risk of bias rating. Future research should examine parent and family related mechanisms of change and modify interventions for improved adherence, such as restricting the number of modules parents are required to complete and teaching key therapeutic strategies such as exposure early in the programme.
AN  - WOS:001349865700001
AU  - Grajdan,
AU  - M.
AU  - M.
AU  - V.
AU  - Etel,
AU  - E.
AU  - Farrell,
AU  - L.
AU  - J.
AU  - Donovan,
AU  - C.
AU  - L.
DB  - November 2024.enl
DO  - 10.1007/s10567-024-00505-3
L1  - internal-pdf://3613622459/s10567-024-00505-3.cleaned.pdf
PY  - 2024
SP  - 49
T2  - Clinical Child and Family Psychology Review
TI  - A Systematic Review of Parental Involvement in Digital Cognitive Behavioural Therapy Interventions for Child Anxiety
UR  - &lt;Go to ISI&gt;://WOS:001349865700001
UR  - https://link.springer.com/article/10.1007/s10567-024-00505-3
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder that is typically managed with pharmacological and psychotherapeutic interventions. In the general population, exposure to nature has been found to have robust beneficial effects on cognitive performance, including attention. With inattention being a factor of the symptomatology of individuals with ADHD, this provides a rationale to investigate the potential benefits of exposure to nature for this population. Four electronic databases (PubMED, PsycINFO, Embase, and Web of Science) were searched for empirical studies investigating the effects of nature on ADHD prevalence and/or symptom severity in populations of school-aged children. Key characteristics, methodologies, and outcomes of included studies were extracted and evaluated. Out of the 458 studies identified, 7 met the inclusion criteria. Despite the large heterogeneity in methodological approaches, the included articles consistently reported that exposure to nature is associated with reduced ADHD diagnoses and symptom severity. Furthermore, when several covariates, such as age, gender, annual household income, parental income, and education level, as well as several pre-natal factors, were controlled for, the relationship between nature and ADHD remained significant. The reviewed literature provides strong support for the benefits of exposure to nature on ADHD in school-aged children.
AN  - 38928982
AU  - Hood,
AU  - M.
AU  - Baumann,
AU  - O.
DB  - Juni 24.enl
DO  - /10.3390/ijerph21060736
L1  - internal-pdf://0204303844/Hood-2024-Could Nature Contribute to the Manag.pdf
PY  - 2024
SP  - 05
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Could Nature Contribute to the Management of ADHD in Children? A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.3390%2fijerph21060736
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-14-00156/article_deploy/ijerph-14-00156.pdf?version=1486465342
VL  - 21
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis aimed to identify and evaluate the quality of randomised controlled trials (RCTs), assessing the efficacy of Social Skills Group Programs (SSGPs) for primary and secondary school aged autistic children and adolescents exploring the influence of informant, setting characteristics and teaching strategies as moderating factors for social outcomes. A search of the electronic databases of Medline, ProQuest, CINAHL, Scopus, and Web of Sciences electronic databases was conducted for the period January 1, 2013 until December 31, 2023 for peer-reviewed RCT studies published in English, evaluating the efficacy of SSGPs for school-aged autistic children and adolescents (6-18 years). Included studies were assessed for methodological quality and efficacy using random effect meta-analysis. Informant analysis and moderator analyses were also conducted investigating the influence of informant, setting characteristics and teaching strategy utilised in the SSGPs on the participants social outcomes. Sixty-five studies were included in the systematic review with 49 studies included in the meta-analysis. Although most studies had strong or good methodological quality, a high possibility of publication bias was detected in the meta-analysis. After statistical adjustments for publication bias were made, findings revealed that SSGPs had no effect on the overall outcomes assessed by included studies on school-aged autistic children and adolescents. However, informant analysis revealed small effects reported by self-report, parent-proxy and researchers. Teaching strategies and setting characteristics were not significant moderators for the efficacy of SSGPs on the social outcomes of autistic children and adolescents. This review highlights the need for improvements in measurement frameworks for assessing social skills in autistic children and adolescents.
AN  - 39690375
AU  - Afsharnejad,
AU  - B.
AU  - Whitehorne
AU  - Smith,
AU  - P.
AU  - Bolte,
AU  - S.
AU  - Milbourn,
AU  - B.
AU  - Girdler,
AU  - S.
DB  - Desember 2024.enl
DO  - /10.1007/s10803-024-06657-z
L1  - internal-pdf://0896333635/5c86ee80-4ad3-4fd2-b865-a4fc2bdd0e4a.pdf
PY  - 2024
SP  - 17
T2  - Journal of Autism &amp; Developmental Disorders
TI  - A Systematic Review of Implicit Versus Explicit Social Skills Group Programs in Different Settings for School-Aged Autistic Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs10803-024-06657-z
UR  - https://link.springer.com/article/10.1007/s10803-024-06657-z
VL  - 17
ER  -
TY  - JOUR
AB  - Background
Cognitive behavioural therapy (CBT) can be effective in the general population of people with schizophrenia. It is still unclear whether CBT can be effectively used in the population of people with a first‐episode or recent‐onset psychosis.

Objectives
To assess the effects of adding cognitive behavioural therapy to standard care for people with a first‐episode or recent‐onset psychosis.

Search methods
We conducted a systematic search on 6 March 2022 in the Cochrane Schizophrenia Group&#039;s Study‐Based Register of Trials, which is based on CENTRAL, MEDLINE, Embase, CINAHL, PsycINFO, PubMed, ClinicalTrials.gov, ISRCTN, and WHO ICTRP.

Selection criteria
We included randomised controlled trials (RCTs) comparing CBT added to standard care vs standard care in first‐episode or recent‐onset psychosis, in patients of any age.

Data collection and analysis
Two review authors (amongst SFM, CC, LK and IB) independently screened references for inclusion, extracted data from eligible studies and assessed the risk of bias using RoB2. Study authors were contacted for missing data and additional information. Our primary outcome was general mental state measured on a validated rating scale. Secondary outcomes included other specific measures of mental state, global state, relapse, admission to hospital, functioning, leaving the study early, cognition, quality of life, satisfaction with care, self‐injurious or aggressive behaviour, adverse events, and mortality.

Main results
We included 28 studies, of which 26 provided data on 2407 participants (average age 24 years). The mean sample size in the included studies was 92 participants (ranging from 19 to 444) and duration ranged between 26 and 52 weeks.

When looking at the results at combined time points (mainly up to one year after start of the intervention), CBT added to standard care was associated with a greater reduction in overall symptoms of schizophrenia (standardised mean difference (SMD) ‐0.27, 95% confidence interval (CI) ‐0.47 to ‐0.08, 20 RCTs, n = 1508, I2 = 68%, substantial heterogeneity, low certainty of the evidence), and also with a greater reduction in positive (SMD ‐0.22, 95% CI ‐0.38 to ‐0.06, 22 RCTs, n = 1565, I&sup2; = 52%, moderate heterogeneity), negative (SMD ‐0.20, 95% CI ‐0.30 to ‐0.11, 22 RCTs, n = 1651, I&sup2; = 0%) and depressive symptoms (SMD ‐0.13, 95% CI ‐0.24 to ‐0.01, 18 RCTs, n = 1182, I&sup2; = 0%) than control. CBT added to standard care was also associated with a greater improvement in the global state (SMD ‐0.34, 95% CI ‐0.67 to ‐0.01, 4 RCTs, n = 329, I&sup2; = 47%, moderate heterogeneity) and in functioning (SMD ‐0.23, 95% CI ‐0.42 to ‐0.05, 18 RCTs, n = 1241, I&sup2; = 53%, moderate heterogeneity, moderate certainty of the evidence) than control.

We did not find a difference between CBT added to standard care and control in terms of number of participants with relapse (relative risk (RR) 0.82, 95% CI 0.57 to 1.18, 7 RCTs, n = 693, I&sup2; = 48%, low certainty of the evidence), leaving the study early for any reason (RR 0.87, 95% CI 0.72 to 1.05, 25 RCTs, n = 2242, I&sup2; = 12%, moderate certainty of the evidence), adverse events (RR 1.29, 95% CI 0.85 to 1.97, 1 RCT, n = 43, very low certainty of the evidence) and the other investigated outcomes.

Authors&#039; conclusions
This review synthesised the latest evidence on CBT added to standard care for people with a first‐episode or recent‐onset psychosis.

The evidence identified by this review suggests that people with a first‐episode or recent‐onset psychosis may benefit from CBT additionally to standard care for multiple outcomes (overall, positive, negative and depressive symptoms of schizophrenia, global state and functioning).

Future studies should better define this population, for which often heterogeneous definitions are used.
AN  - CD015331
AU  - Mayer,
AU  - S.
AU  - F.
AU  - Corcoran,
AU  - C.
AU  - Kennedy,
AU  - L.
AU  - Leucht,
AU  - S.
AU  - Bighelli,
AU  - I.
DB  - April 24.enl
DO  - 10.1002/14651858.CD015331.pub2
KW  - *Cognitive Behavioral Therapy
KW  - *Psychotic Disorders [therapy]
KW  - Adult
KW  - Aggression
KW  - Cognition
KW  - Humans
KW  - Recurrence
KW  - Young Adult
L1  - internal-pdf://0078165684/Mayer_et_al-2024-Cochrane_Database_of_Systemat.pdf
N1  - [Schizophrenia]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive behavioural therapy added to standard care for first‐episode and recent‐onset psychosis
UR  - http://dx.doi.org/10.1002/14651858.CD015331.pub2
ER  -
TY  - JOUR
AB  - While problematic behaviors can hamper children&#039;s early positive development, the teacher-child relationship can play a crucial role in mitigating children&#039;s externalizing problem behavior (EPB).This review aims to systematically examine and synthesize evidence on the effectiveness of interventions designed to enhance teacher-child interactions (TCIs) and assess their impact on reducing EPB among children in childcare settings. Systematic literature searches were performed on four electronic databases (EBSCO, ERIC, SCOPUS, and WOS). A complementary search of clinical trial registries (clinicaltrials.gov) was performed. The studies reported on interventions targeting the promotion of TCI to reduce children&#039;s EPB in childcare settings. The children were aged 0-6 years, and their EPB was assessed using self-report questionnaires and/or observational coding instruments. The risk of bias was evaluated using the Joanna Briggs Institute&#039;s Critical Appraisal Tool. The standardized mean differences were pooled using random effects, and a moderator analysis was conducted. The review included 26 studies, 12 of which were included in a meta-analysis, revealing a significant decrease in children&#039;s EPB (SMD = -0.240; 95% CI = [-0.362, -0.117]; p = 0.001). Tier-2 interventions implemented within the Multi-Tiered Systems of Support (MTSS) framework were particularly effective (SMD = -0.508; 95% CI: [-0.755, -0.261]). Furthermore, interventions that integrated video components also showed significant effectiveness (SMD = -0.303; 95% CI: [-0.434, -0.172]). This review emphasizes the importance of enhancing TCIs to reduce children&#039;s EPB and recommends innovative training methods and long-term follow-up studies for improved effectiveness.
AN  - WOS:001360172600001
AU  - Harti,
AU  - F.
AU  - Chausseboeuf,
AU  - L.
AU  - Santelices,
AU  - M.
AU  - P.
AU  - Wendland,
AU  - J.
DB  - November 2024.enl
DO  - 10.1007/s10643-024-01773-y
L1  - internal-pdf://3728573635/s10643-024-01773-y.cleaned.pdf
PY  - 2024
SP  - 39
T2  - Early Childhood Education Journal
TI  - Modalities and Effectiveness of Interventions Aimed at Promoting Teacher-Child Interaction to Reduce Children&#039;s Externalizing Behavior Problems in Childcare Centers: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001360172600001
UR  - https://link.springer.com/article/10.1007/s10643-024-01773-y
ER  -
TY  - JOUR
AB  - OBJECTIVE: The authors sought to explore the role of iron supplementation in the management of neurodevelopmental disorders among children and youths. 

METHODS: A systematic review in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was undertaken. A subset of results was suitable for meta-analysis. The quality of the evidence and strength of the clinical recommendations were assessed by using the Grading of Recommendations, Assessment, Development, and Evaluation method, and critical appraisal was conducted with the Joanna Briggs Institute critical appraisal tools. 

RESULTS: Nine articles met inclusion criteria. These articles included studies of attention-deficit hyperactivity disorder (ADHD) (N=7), autism spectrum disorder (N=1), and Tourette&#039;s syndrome (N=1). Three randomized controlled trials evaluating iron supplementation for ADHD hyperactivity symptom severity (124 participants: placebo, N=56; supplement, N=68) met inclusion criteria for a meta-analysis. Effect sizes for the placebo and supplement groups were moderate (Cohen&#039;s d=0.76) and large (Cohen&#039;s d=1.70), respectively, although these differences were not significant. The impact of iron supplementation on inattentive ADHD symptom severity was examined in two trials (75 participants: placebo, N=31; supplement, N=44). Large, nonsignificant effect sizes were demonstrated for the placebo (Cohen&#039;s d=1.66) and supplementation (Cohen&#039;s d=3.19) groups. The quality of the evidence and strength of the clinical recommendations were considered very low. 

CONCLUSIONS: Further research is needed to examine the role of iron supplementation in the management of ADHD and neurodevelopmental disorders more generally. Additionally, iron supplementation comes with risks, including death in the case of overdose.
AN  - 38343311
AU  - Elliott,
AU  - S.
AU  - D.
AU  - Vickers,
AU  - M.
AU  - L.
AU  - McKeon,
AU  - G.
AU  - Eriksson,
AU  - L.
AU  - Malacova,
AU  - E.
AU  - Scott,
AU  - J.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1176/appi.neuropsych.20230081
L1  - internal-pdf://0590290472/elliott-et-al-2024-iron-supplementation-in-man.pdf
PY  - 2024
SP  - appineuropsych20230081
T2  - Journal of Neuropsychiatry &amp; Clinical Neurosciences
TI  - Iron Supplementation in Management of Neurodevelopmental Disorders: Systematic Review, Meta-Analysis, and Qualitative Synthesis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38343311
ER  -
TY  - JOUR
AB  - Purpose of Review
This review explores the role of vitamin D in the pathophysiology and management of attention-deficit/hyperactivity disorder (ADHD). Given the localization of Vitamin D receptors in brain regions implicated in ADHD and vitamin D&#039;s role in neurotransmitter regulation, this review synthesizes research that examines vitamin D&#039;s relationship to the development and therapeutic outcomes of ADHD.

Recent Findings
A systematic literature search resulted in the selection of seven reviews meeting the inclusion criteria. These reviews summarize original studies that are focused on: 1. The association between prenatal Vitamin D levels and ADHD in offspring, with meta-analyses suggesting that higher maternal serum Vitamin D levels reduce the likelihood and severity of ADHD symptoms in children. 2. Comparative analyses of Vitamin D levels in children with ADHD versus those without, showing lower Vitamin D levels in affected children. 3. Intervention studies where Vitamin D supplementation was linked to improvements in ADHD symptoms.

Results
Seven reviews met the inclusion criteria, from which the main results were: 1. Meta-analyses suggested a decreased risk of offspring with ADHD and fewer or less severe ADHD-related features later in life with higher maternal serum Vitamin D levels. 2. Children with ADHD were found to have lower serum Vitamin D levels than children without ADHD across the original literature. 3. Vitamin D supplementation was associated with improvements in ADHD symptoms.

Summary
The literature supports relationships between Vitamin D levels and ADHD, both in its emergence and clinical management. Despite these findings, further research is indicated. There remains a need for additional well-powered randomized clinical trials to provide evidence and guide clinical practice regarding the use of Vitamin D in ADHD and to ensure that interventions are efficacious, well tolerated and tailored to individual patients.
AN  - WOS:001242785700001
AU  - Kitaneh,
AU  - R.
AU  - Jalilian-Khave,
AU  - L.
AU  - Ysrayl,
AU  - B.
AU  - B.
AU  - Borelli,
AU  - A.
AU  - Funaro,
AU  - M.
AU  - C.
AU  - Potenza,
AU  - M.
AU  - N.
AU  - Angarita,
AU  - G.
AU  - A.
DB  - Juli 2024.enl
DO  - 10.1007/s40473-024-00278-7
L1  - internal-pdf://3773578495/Kitaneh-2024-The Relationship Between Vitamin.pdf
PY  - 2024
SP  - 18
T2  - Current Behavioral Neuroscience Reports
TI  - The Relationship Between Vitamin D and the Development and Treatment of Attention-Deficit Hyperactivity Disorder: An Overview of Systematic Reviews
UR  - &lt;Go to ISI&gt;://WOS:001242785700001
UR  - https://link.springer.com/article/10.1007/s40473-024-00278-7
UR  - https://link.springer.com/content/pdf/10.1007/s40473-024-00278-7.pdf
ER  -
TY  - JOUR
AB  - OBJECTIVES: Anxiety disorders affect 20%-50% of youth with chronic medical conditions (CMCs) and can interfere with medical care and treatment outcomes. Psychological therapies are typically designed for youth without CMCs; thus, this systematic review (Open Science Framework preregistration osf.io/a52nd/) assesses the effect of psychological therapies on anxiety, functional impairment and health-related quality of life (HRQOL) in this unique population. 

METHODS: We included randomized controlled trials of psychological therapies vs. any comparator for youth (ages 24 and younger) with CMCs that assessed child anxiety. We excluded studies of adults and those not in English. Medline, Embase, PsycInfo, and CENTRAL databases were searched, studies were screened using COVIDENCE software, and meta-analysis was undertaken in R. Study quality was assessed using the Cochrane Risk of Bias tool, version 2. Quality of evidence was assessed using the GRADE system.

RESULTS: Thirty-three studies with 2676 participants (ages 5-21 years) were included in the meta-analysis. Nearly all had at least some risk of bias. Overall, psychological interventions resulted in lower anxiety (Hedges&#039; g = -0.48 [-0.71; -0.25]), but did not have a significant effect on functional impairment or HRQOL. Based on the GRADE criteria, we have moderate confidence in these results. Treatments with higher risk of bias and those with live therapist components had greater effects on anxiety. 

CONCLUSIONS: Psychological interventions may be effective for improving anxiety for children and youth with CMCs, particularly those with a live therapist. More high-quality studies are needed to understand what components produce the best outcomes for patients.
AN  - 39607990
AU  - Tran,
AU  - S.
AU  - T.
AU  - Bieniak,
AU  - K.
AU  - Bedree,
AU  - H.
AU  - Adler,
AU  - M.
AU  - Ogunmona,
AU  - S.
AU  - Kovar-Gough,
AU  - I.
AU  - Ma,
AU  - W.
AU  - Thabrew,
AU  - H.
AU  - Cunningham,
AU  - N.
AU  - R.
DB  - Desember 2024.enl
DO  - /10.1093/jpepsy/jsae097
L1  - internal-pdf://3431135418/551513e5-e559-4def-bad6-57abbab84088.pdf
PY  - 2024
SP  - 28
T2  - Journal of Pediatric Psychology
TI  - Systematic review and meta-analysis of the effect of psychological interventions on anxiety in children and youth with chronic medical conditions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1093%2fjpepsy%2fjsae097
VL  - 28
ER  -
TY  - JOUR
AB  - Cognitive behavioral therapy (CBT) is an evidenced-based treatment for sleep concerns but may be insufficient on its own to resolve adolescent sleep problems - combining this treatment with motivational interviewing may result in more robust improvements to sleep in adolescents and young adults (AYA). This study aimed to conduct the first meta-analysis of integrated CBT and motivational interviewing (MI) for AYA sleep concerns. Following PRISMA guidelines, PsycINFO, PubMed, and Google Scholar were searched through January 2024. Cohen&#039;s d was computed for effect sizes. Eligible articles included AYA utilized an integration of CBT and MI, reported quantitative outcomes related to sleep, and were published in peer-reviewed journals and available in English. Four studies were eligible for the meta-analysis (N = 435). Results showed a small-medium effect size for reduced daytime sleepiness (d = 0.39, p = .001) and increased total sleep time (d = 0.25, p = .008) following integrated CBT and MI. Risk of bias was assessed using CMA. The findings suggest integrated CBT and MI is beneficial for AYA daytime sleepiness and sleep duration, more effective than CBT alone and other control groups. These findings contribute to the understanding of effective interventions for AYA sleep concerns, offer practical insights for practitioners, and highlight the need for further investigation into the integration of CBT and MI.
AN  - WOS:001375255700001
AU  - Vrabec,
AU  - A.
AU  - Milligan,
AU  - M.
AU  - A.
AU  - Antshel,
AU  - K.
AU  - M.
AU  - Kidwell,
AU  - K.
AU  - M.
DB  - Desember 2024.enl
DO  - 10.1177/13591045241308983
L1  - internal-pdf://1724775586/vrabec-et-al-2024-a-meta-analytic-review-of-co.pdf
PY  - 2024
SP  - 16
T2  - Clinical Child Psychology and Psychiatry
TI  - A meta-analytic review of cognitive behavior therapy and motivational interviewing for adolescent and young adult sleep concerns
UR  - &lt;Go to ISI&gt;://WOS:001375255700001
UR  - https://journals.sagepub.com/doi/10.1177/13591045241308983
ER  -
TY  - JOUR
AB  - Importance Neurofeedback has been proposed for the treatment of attention-deficit/hyperactivity disorder (ADHD) but the efficacy of this intervention remains unclear. Objective To conduct a meta-analysis of randomized clinical trials (RCTs) using probably blinded (ie, rated by individuals probably or certainly unaware of treatment allocation) or neuropsychological outcomes to test the efficacy of neurofeedback as a treatment for ADHD in terms of core symptom reduction and improved neuropsychological outcomes. Data Sources PubMed (MEDLINE), Ovid (PsycInfo, MEDLINE, Embase + Embase Classic), and Web of Science, as well as the reference lists of eligible records and relevant systematic reviews, were searched until July 25, 2023, with no language limits. Study Selection Parallel-arm RCTs investigating neurofeedback in participants of any age with a clinical ADHD or hyperkinetic syndrome diagnosis were included. Data Extraction and SynthesisStandardized mean differences (SMDs) with Hedges g correction were pooled in random effects meta-analyses for all eligible outcomes. Main Outcomes and Measures The primary outcome was ADHD total symptom severity assessed at the first postintervention time point, focusing on reports by individuals judged probably or certainly unaware of treatment allocation (probably blinded). Secondary outcomes were inattention and/or hyperactivity-impulsivity symptoms and neuropsychological outcomes postintervention and at a longer-term follow-up (ie, after the last follow-up time point). RCTs were assessed with the Cochrane risk of bias tool version 2.0. Results A total of 38 RCTs (2472 participants aged 5 to 40 years) were included. Probably blinded reports of ADHD total symptoms showed no significant improvement with neurofeedback (k = 20; n = 1214; SMD, 0.04; 95% CI, -0.10 to 0.18). A small significant improvement was seen when analyses were restricted to RCTs using established standard protocols (k = 9; n = 681; SMD, 0.21; 95% CI, 0.02 to 0.40). Results remained similar with adults excluded or when analyses were restricted to RCTs where cortical learning or self-regulation was established. Of the 5 neuropsychological outcomes analyzed, a significant but small improvement was observed only for processing speed (k = 15; n = 909; SMD, 0.35; 95% CI, 0.01 to 0.69). Heterogeneity was generally low to moderate. Conclusions and Relevance Overall, neurofeedback did not appear to meaningfully benefit individuals with ADHD, clinically or neuropsychologically, at the group level. Future studies seeking to identify individuals with ADHD who may benefit from neurofeedback could focus on using standard neurofeedback protocols, measuring processing speed, and leveraging advances in precision medicine, including neuroimaging technology.
AN  - WOS:001377075300001
AU  - Westwood,
AU  - S.
AU  - J.
AU  - Aggensteiner,
AU  - P.
AU  - M.
AU  - Kaiser,
AU  - A.
AU  - Nagy,
AU  - P.
AU  - Donno,
AU  - F.
AU  - Merkl,
AU  - D.
AU  - Balia,
AU  - C.
AU  - Goujon,
AU  - A.
AU  - Bousquet,
AU  - E.
AU  - Capodiferro,
AU  - A.
AU  - M.
AU  - Derks,
AU  - L.
AU  - Purper-Ouakil,
AU  - D.
AU  - Carucci,
AU  - S.
AU  - Holtmann,
AU  - M.
AU  - Brandeis,
AU  - D.
AU  - Cortese,
AU  - S.
AU  - Sonuga-Barke,
AU  - E.
AU  - J.
AU  - S.
AU  - European,
AU  - Adhd
AU  - Guidelines
AU  - Grp
AU  - Eagg
DB  - Desember 2024.enl
DO  - 10.1001/jamapsychiatry.2024.3702
L1  - internal-pdf://1930754937/2600b695-aacf-42a4-a4c4-5c32d838ef9f.pdf
PY  - 2024
SP  - 12
T2  - JAMA Psychiatry
TI  - Neurofeedback for Attention-Deficit/Hyperactivity Disorder
UR  - &lt;Go to ISI&gt;://WOS:001377075300001
UR  - https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2827733
ER  -
TY  - JOUR
AB  - BACKGROUND: Interventions supporting parents of young children often target parenting or parental mental health separately. Multi-component parenting and parental mental health interventions have the potential to improve parenting practices, mental health, and early childhood development. We aimed to examine their impact on child and parent outcomes. 

METHODS: In this systematic review and meta-analysis, we searched MEDLINE, Embase, Web of Science Core Collection, APA PsycINFO, CINAHL Complete, the Cochrane Central Register of Controlled Trials, and the Global Health Database from inception to Jan 23, 2024. Eligible studies were randomised controlled trials of interventions explicitly targeting parenting behaviours and parental mental health antenatally or in children&#039;s first 3 years of life. Screening, extraction, and quality assessment were done independently by two authors. Primary outcomes were cognitive and social-emotional functioning in children and depressive symptoms in parents, meta-analysed as standardised mean differences (SMDs), relative to control. This study is registered with PROSPERO, CRD42022302848. 

FINDINGS: We found 5843 records. After screening 2636 (45.1%) titles and abstracts, we manually identified and screened three additional articles and excluded 2177 records. After screening 462 full-length articles, 25 articles, representing a sample size of 8520 children and caregivers, were included. At baseline, mean caregiver age was 27.7 years (SD 5.9) and mean child age (excluding those enrolled during pregnancy) was 14.4 months (8.0). Interventions lasted a mean of 14 months (SD 11) and used a mean of 3.7 behaviour change techniques (2.0). Most interventions dedicated more time to parenting behaviours than to parental mental health. We found significant intervention effects on children&#039;s cognitive (SMD 0.19 [95% CI 0.04 to 0.34]; I&lt;sup&gt;2&lt;/sup&gt;=69%) and social-emotional (0.26 [0.17 to 0.34]; I&lt;sup&gt;2&lt;/sup&gt;=47%) outcomes but not on depressive symptoms in female caregivers (-0.18 [-0.36 to 0.002]; I&lt;sup&gt;2&lt;/sup&gt;=86%) relative to control conditions. Risk of bias across studies was moderate, and we found heterogeneity across results. 

INTERPRETATION: Multi-component parenting and mental health interventions had a positive effect on child cognitive and social-emotional outcomes, but not on depressive symptoms in parents, suggesting that other factors might contribute to positive ECD outcomes. Interventions might lack adequate focus on mental health to make a discernible impact, highlighting a need for future studies to differentiate and assess contributions of parenting and mental health components to understand independent and collective effects on family outcomes. 

FUNDING: Canadian Institutes of Health Research.
AN  - 39142740
AU  - Al
AU  - Sager,
AU  - A.
AU  - Goodman,
AU  - S.
AU  - H.
AU  - Jeong,
AU  - J.
AU  - Bain,
AU  - P.
AU  - A.
AU  - Ahun,
AU  - M.
AU  - N.
DB  - August 2024.enl
DO  - /10.1016/S2352-4642(24)00134-2
L1  - internal-pdf://1546937713/1-s2.0-S2352464224001342-main.cleaned.pdf
PY  - 2024
SP  - 656-669
T2  - The Lancet Child &amp; Adolescent Health
TI  - Effects of multi-component parenting and parental mental health interventions on early childhood development and parent outcomes: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1016%2fS2352-4642%2824%2900134-2
VL  - 8
ER  -
TY  - JOUR
AB  - Children with autism spectrum disorder (ASD) often have motor impairments. A promising strategy to improve motor and social functioning in children with ASD may be an aquatic intervention because of the properties of water. This systematic review investigated the characteristics and effects of aquatic interventions on motor and social skills in children with ASD. Searches in six databases on studies conducted between 2000 and 2023 resulted in 19 intervention studies involving 429 children aged 3 to 17 years with ASD. Best evidence syntheses and meta-analyses were used to evaluate the effects. Aquatic interventions guided by a combination of professionals in influencing behavior and in aquatic skills improved motor and social skills and significantly decreased autistic behavior in children with ASD.
AN  - WOS:001229211600001
AU  - vant
AU  - Hooft,
AU  - P.
AU  - Moeijes,
AU  - J.
AU  - Hartman,
AU  - C.
AU  - van
AU  - Busschbach,
AU  - J.
AU  - Hartman,
AU  - E.
DB  - Juni 24.enl
DO  - 10.1007/s40489-024-00464-z
L1  - internal-pdf://1954049993/vant Hooft-2024-Aquatic Interventions to Impro.pdf
PY  - 2024
SP  - 21
T2  - Review Journal of Autism and Developmental Disorders
TI  - Aquatic Interventions to Improve Motor and Social Functioning in Children with ASD: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001229211600001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-024-00464-z.pdf
ER  -
TY  - JOUR
AB  - OBJECTIVE: The number of forced migrants has been rising for years. Many forced migrants suffer from post-traumatic stress disorder (PTSD), depression, and/or anxiety and need treatment. Here, we evaluate the effectiveness of psychological interventions (CBT, EMDR, expressive/art, mindfulness, mixed elements, NET and psychoeducation) in reducing symptoms of PTSD, depression, and anxiety in forced migrants.

DESIGN AND DATA SOURCES: Systematic searches in PubMed and Web of Science and searches of preprint servers and grey literature were performed (final search date: 1 September 2023). Random-effects frequentist and Bayesian meta-analyses were used for data synthesis. 

RESULTS: We included 84 studies on treatment effects in adults (pooled N = 6302) and 32 on children and adolescents (pooled N = 1097). Our data show a reduction in symptoms of PTSD, depression and anxiety symptoms in both adults and child/adolescent forced migrants. Pooled pre- to post-treatment effects (effect size Cohen&#039;s d) ranged from -1.03 to -0.26 for PTSD, from -0.91 to -0.11 for depression and from -0.91 to -0.60 for anxiety, without there being differences in outcome per study design (i.e., RCT comparison vs. non-RCT comparison vs. single arm treatment study). Treatment effects remained evident over follow-up, and not a single type of treatment stood out as being superior to other treatment types. Structural differences in populations (e.g., regarding country of origin) over studies, however, could have hampered the validity of the comparisons between study characteristics such as treatment type. 

CONCLUSION: Our findings support the effectiveness of psychological treatment in adult and child/adolescent forced migrants.
AN  - 39152566
AU  - Molendijk,
AU  - M.
AU  - Baart,
AU  - C.
AU  - Schaffeld,
AU  - J.
AU  - Akcakaya,
AU  - Z.
AU  - Ronnau,
AU  - C.
AU  - Kooistra,
AU  - M.
AU  - de
AU  - Kleine,
AU  - R.
AU  - Strater,
AU  - C.
AU  - Mooshammer,
AU  - L.
DB  - August 2024.enl
DO  - /10.1002/cpp.3042
L1  - internal-pdf://1180787519/Molendijk-2024-Psychological Interventions for.pdf
PY  - 2024
SP  - e3042
T2  - Clinical Psychology &amp; Psychotherapy
TI  - Psychological Interventions for PTSD, Depression, and Anxiety in Child, Adolescent and Adult Forced Migrants: A Systematic Review and Frequentist and Bayesian Meta-Analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1002%2fcpp.3042
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpp.3042?download=true
VL  - 31
ER  -
TY  - JOUR
AB  - This study examines the effects of OAE on adolescent social and emotional wellbeing and their contributors. Intervention studies (single or multi-arm) assessing the effects of OAE on wellbeing were included. Meta-analysis was conducted on outcomes of interest, and the Cochrane Risk of Bias (RoB) Tool assessed RoB in multi-arm studies. Four studies assessed within-group change (n = 368), and six assessed between-group change (n = 1,143). Findings indicate significant between-group improvements in resilience, self-esteem and social belonging when OAE was compared to no intervention, but no self-efficacy and overall wellbeing changes were observed. Studies were at high risk of bias, and the credibility of the presented evidence was very low. OAE may benefit adolescents&#039; interpersonal connectedness and psychological strengths, but we cannot be confident in effect estimates due to bias and low-quality evidence. As such, this study is significant in highlighting the need for more research rigour in OAE.
AN  - WOS:001287707000001
AU  - Down,
AU  - M.
AU  - J.
AU  - A.
AU  - Picknoll,
AU  - D.
AU  - Edwards,
AU  - T.
AU  - Farringdon,
AU  - F.
AU  - Hoyne,
AU  - G.
AU  - Piggott,
AU  - B.
AU  - Murphy,
AU  - M.
AU  - C.
DB  - September 2024.enl
DO  - 10.1080/14729679.2024.2386350
L1  - internal-pdf://3376173327/Outdoor adventure education for adolescent soc.pdf
PY  - 2024
SP  - 29
T2  - Journal of Adventure Education and Outdoor Learning
TI  - Outdoor adventure education for adolescent social and emotional wellbeing: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001287707000001
UR  - https://www.tandfonline.com/doi/full/10.1080/14729679.2024.2386350
ER  -
TY  - JOUR
AB  - Among the many social and emotional learning (SEL) interventions available, mindfulness-based interventions (MBIs) have become increasingly popular, particularly for preadolescent children who were once thought to not possess the metacognitive abilities or cognitive resources to benefit from such training. Although previous research syntheses indicate that MBIs show promise in promoting positive outcomes across a range of domains, the effectiveness of MBIs for preadolescent children may be masked by the effects of older children who have comprised the majority of samples in past meta-analyses. Hence, to better understand the impact of mindfulness-based training on preadolescent children (ages 6-12 years), the present study reviewed treatment effect estimates across a range of outcomes, including mindfulness, attention, metacognition and cognitive flexibility, emotional and behavioral regulation, academic achievement and school functioning, positive emotion and self-appraisal, negative emotion and subjective distress, externalizing problems, internalizing problems, social competence and prosocial behavior, and physical health. Thirty-two studies (n&lt;sub&gt;participants&lt;/sub&gt; = 3640) were identified and included in a random-effects meta-analyses. The results from multiple meta-analytical analyses conducted in the present study suggest that preadolescents have experienced significant benefits across attention, emotional and behavioral regulation, positive emotion and self-appraisal, and social competence and prosocial behavior (g = 0.19 to 0.39). However, the overall effect was deemed small (g = 0.34). Due to the lack of comparison studies with SEL interventions, it remains unclear whether MBIs are as effective as traditional approaches in promoting healthy development and academic achievement for preadolescent children. Additionally, results from the present meta-analysis suggest various recommendations for future studies to ensure a continued growth in understanding how MBIs can be used with children.
AN  - 38143094
AU  - Kander,
AU  - T.
AU  - N.
AU  - Lawrence,
AU  - D.
AU  - Fox,
AU  - A.
AU  - Houghton,
AU  - S.
AU  - Becerra,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jsp.2023.101261
L1  - internal-pdf://1849896729/1-s2.0-S0022440523000894-main.cleaned.pdf
PY  - 2024
SP  - 101261
T2  - Journal of School Psychology
TI  - Mindfulness-based interventions for preadolescent children: A comprehensive meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=38143094
UR  - https://www.sciencedirect.com/science/article/pii/S0022440523000894?via%3Dihub
VL  - 102
ER  -
TY  - JOUR
AB  - BACKGROUND: To evaluate the effects of different interventions on adolescent internet addiction, a meta-analysis and network meta-analysis were performed to determine the possible intervention effects of these interventions. 

METHODS: Computer searches of the China National Knowledge Network, Wanfang, VIP, EMBASE, PubMed, Web of Science, EBSCO, and Cochrane Library databases were performed. The relevant randomized controlled trials were designed to assess the effects of interventions on adolescent internet addiction. The retrieval period ranged from the establishment of the database to January 31, 2024. Literature screening, data extraction, and bias risk assessment were carried out independently by two researchers. CMA 3.3, Stata 17.0 software and Review Manager 5.3 were used for the data analysis. 

RESULTS: A total of 89 studies with 6876 samples were included. A traditional meta-analysis of 51 single interventions and controlled studies revealed that sports intervention, cognitive behavior therapy, family therapy, mindfulness intervention, attention bias training and group counseling significantly improved adolescent Internet addiction [standardized mean difference (SMD)=-1.75, 95% CI (-2.07, -1.44), p&lt;0.01; I&lt;sup&gt;2&lt;/sup&gt;=94%] compared to no-treatment groups. A network meta-analysis showed that combined intervention (Sucra=93.5) had the highest probability of being the best intervention for adolescent Internet addiction, and acupuncture interventions showed the most promise as a single intervention modality; however, due to the limited number of studies, we believe that sports intervention could be the most appropriate single intervention.

DISCUSSION: The evidence provided by existing studies shows that compared with other single interventions, combined interventions have the greatest effect on adolescent IA, and sports may be the best single intervention. However, because of the limitations of sample size and quality of individual studies, the strength of the evidence still needs to be further verified by additional standardized and high-quality studies.
AN  - 39147163
AU  - Zhou,
AU  - Z.
AU  - Li,
AU  - C.
AU  - Yuan,
AU  - J.
AU  - Zang,
AU  - L.
DB  - August 2024.enl
DO  - /10.1016/j.jad.2024.08.064
L1  - internal-pdf://3610994549/1-s2.0-S0165032724012795-main (1).pdf
PY  - 2024
SP  - 13
T2  - Journal of Affective Disorders
TI  - Effectiveness of sports intervention: A meta-analysis of the effects of different interventions on adolescent internet addiction
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jad.2024.08.064
VL  - 13
ER  -
TY  - JOUR
AB  - BACKGROUND: The high prevalence of unhealthy movement behaviors among young children remains a global public health issue. eHealth is considered a cost-effective approach that holds great promise for enhancing health and related behaviors. However, previous research on eHealth interventions aimed at promoting behavior change has primarily focused on adolescents and adults, leaving a limited body of evidence specifically pertaining to preschoolers. 

OBJECTIVE: This review aims to examine the effectiveness of eHealth interventions in promoting 24-hour movement behaviors, specifically focusing on improving physical activity (PA) and sleep duration and reducing sedentary behavior among preschoolers. In addition, we assessed the moderating effects of various study characteristics on intervention effectiveness. 

METHODS: We searched 6 electronic databases (PubMed, Ovid, SPORTDiscus, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials) for experimental studies with a randomization procedure that examined the effectiveness of eHealth interventions on 24-hour movement behaviors among preschoolers aged 2 to 6 years in February 2023. The study outcomes included PA, sleep duration, and sedentary time. A meta-analysis was conducted to assess the pooled effect using a random-effects model, and subgroup analyses were conducted to explore the potential effects of moderating factors such as intervention duration, intervention type, and risk of bias (ROB). The included studies underwent a rigorous ROB assessment using the Cochrane ROB tool. Moreover, the certainty of evidence was evaluated using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) assessment. 

RESULTS: Of the 7191 identified records, 19 (0.26%) were included in the systematic review. The meta-analysis comprised a sample of 2971 preschoolers, which was derived from 13 included studies. Compared with the control group, eHealth interventions significantly increased moderate to vigorous PA (Hedges g=0.16, 95% CI 0.03-0.30; P=.02) and total PA (Hedges g=0.37, 95% CI 0.02-0.72; P=.04). In addition, eHealth interventions significantly reduced sedentary time (Hedges g=-0.15, 95% CI -0.27 to -0.02; P=.02) and increased sleep duration (Hedges g=0.47, 95% CI 0.18-0.75; P=.002) immediately after the intervention. However, no significant moderating effects were observed for any of the variables assessed (P&gt;.05). The quality of evidence was rated as &quot;moderate&quot; for moderate to vigorous intensity PA and sedentary time outcomes and &quot;low&quot; for sleep outcomes. 

CONCLUSIONS: eHealth interventions may be a promising strategy to increase PA, improve sleep, and reduce sedentary time among preschoolers. To effectively promote healthy behaviors in early childhood, it is imperative for future studies to prioritize the development of rigorous comparative trials with larger sample sizes. In addition, researchers should thoroughly examine the effects of potential moderators. There is also a pressing need to comprehensively explore the long-term effects resulting from these interventions. TRIAL REGISTRATION: PROSPERO CRD42022365003; http://tinyurl.com/3nnfdwh3.
AN  - 38381514
AU  - Jiang,
AU  - S.
AU  - Ng,
AU  - J.
AU  - Y.
AU  - Y.
AU  - Chong,
AU  - K.
AU  - H.
AU  - Peng,
AU  - B.
AU  - Ha,
AU  - A.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.2196/52905
L1  - internal-pdf://0492711493/pdf.cleaned (10).pdf
PY  - 2024
SP  - e52905
T2  - Journal of Medical Internet Research
TI  - Effects of eHealth Interventions on 24-Hour Movement Behaviors Among Preschoolers: Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38381514
VL  - 26
ER  -
TY  - JOUR
AB  - Play-based interventions are gaining popularity amongst autistic children. Parents are uniquely placed to deliver these interventions as they are most familiar with their child&#039;s strengths and challenges. Accordingly, reporting the effectiveness of play-based interventions and/or parent-delivered or mediated early-year interventions have been popular topics in the literature in the last decade. Despite this, little is known about the efficacy of parent-mediated play-based interventions on the developmental outcomes of autistic children. To close this gap in knowledge, we conducted a systematic review and meta-analysis of randomised controlled trials and quasi-experiments focusing on social communication skills, language skills, and autistic characteristics of preschool autistic children (0-6-year-old) in non-educational settings. Overall, 26 studies met the inclusion criteria 21 of which were included in the synthesis. Of the included studies, 20 studies reported social communication skills, 15 studies reported language skills, and 12 studies reported autistic characteristics. Pooling effect sizes across the included studies showed that parent-mediated play-based interventions were effective on social communication (d = .63) and language skills (d = .40) as well as autistic characteristics (d = - .19) of preschool autistic children. Our findings suggest that parent-mediated play-based interventions hold promise for improving social functioning and related autistic characteristics for preschool autistic children.
AN  - WOS:001222365400001
AU  - Deniz,
AU  - E.
AU  - Francis,
AU  - G.
AU  - Torgerson,
AU  - C.
AU  - Toseeb,
AU  - U.
DB  - Juni 24.enl
DO  - 10.1007/s40489-024-00463-0
L1  - internal-pdf://3770117276/Deniz-2024-Parent-Mediated Play-Based Interven.pdf
PY  - 2024
SP  - 21
T2  - Review Journal of Autism and Developmental Disorders
TI  - Parent-Mediated Play-Based Interventions to Improve Social Communication and Language Skills of Preschool Autistic Children: A Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001222365400001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-024-00463-0.pdf
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Home treatment in child and adolescent psychiatry offers an alternative to conventional inpatient treatment by involving the patient&#039;s family, school, and peers more directly in therapy. Although several reviews have summarised existing home treatment programmes, evidence of their effectiveness remains limited and data synthesis is lacking. 

**METHODS**: We conducted a meta-analysis on the effectiveness of home treatment compared with inpatient treatment in child and adolescent psychiatry, based on a systematic search of four databases (PubMed, CINAHL, PsychINFO, Embase). Primary outcomes were psychosocial functioning and psychopathology. Additional outcomes included treatment satisfaction, duration, costs, and readmission rates. Group differences were expressed as standardised mean differences (SMD) in change scores. We used three-level random-effects meta-analysis and meta-regression and conducted both superiority and non-inferiority testing. 

**RESULTS**: We included 30 studies from 13 non-overlapping samples, providing data from 1795 individuals (mean age: 11.95 +/- 2.33 years; 42.5% female). We found no significant differences between home and inpatient treatment for postline psychosocial functioning (SMD = 0.05 [- 0.18; 0.30], p = 0.68, I&lt;sup&gt;2&lt;/sup&gt; = 98.0%) and psychopathology (SMD = 0.10 [- 0.17; 0.37], p = 0.44, I&lt;sup&gt;2&lt;/sup&gt; = 98.3%). Similar results were observed from follow-up data and non-inferiority testing. Meta-regression showed better outcomes for patient groups with higher levels of psychopathology at baseline and favoured home treatment over inpatient treatment when only randomised controlled trials were considered. 

**CONCLUSIONS**: This meta-analysis found no evidence that home treatment is less effective than conventional inpatient treatment, highlighting its potential as an effective alternative in child and adolescent psychiatry. The generalisability of these findings is reduced by limitations in the existing literature, and further research is needed to better understand which patients benefit most from home treatment. 

TRIAL REGISTRATION: Registered at PROSPERO (CRD42020177558), July 5, 2020.
AN  - 38867231
AU  - Graf,
AU  - D.
AU  - Sigrist,
AU  - C.
AU  - Boege,
AU  - I.
AU  - Cavelti,
AU  - M.
AU  - Koenig,
AU  - J.
AU  - Kaess,
AU  - M.
DB  - Juni 24.enl
DO  - /10.1186/s12916-024-03448-2
L1  - internal-pdf://0402942773/Graf-2024-Effectiveness of home treatment in c.pdf
PY  - 2024
SP  - 241
T2  - BMC Medicine
TI  - Effectiveness of home treatment in children and adolescents with psychiatric disorders-systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1186%2fs12916-024-03448-2
UR  - https://bmcmedicine.biomedcentral.com/counter/pdf/10.1186/s12916-024-03448-2.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - Eating disorders (EDs) are known to be associated with high mortality and often chronic and severe course, but a recent comprehensive systematic review of their outcomes is currently missing. In the present systematic review and meta-analysis, we examined cohort studies and clinical trials published between 1980 and 2021 that reported, for DSM/ICD-defined EDs, overall ED outcomes (i.e., recovery, improvement and relapse, all-cause and ED-related hospitalization, and chronicity); the same outcomes related to purging, binge eating and body weight status; as well as mortality. We included 415 studies (N=88,372, mean age: 25.7+/-6.9 years, females: 72.4%, mean follow-up: 38.3+/-76.5 months), conducted in persons with anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), other specified feeding and eating disorders (OSFED), and/or mixed EDs, from all continents except Africa. In all EDs pooled together, overall recovery occurred in 46% of patients (95% CI: 44-49, n=283, mean follow-up: 44.9+/-62.8 months, no significant ED-group difference). The recovery rate was 42% at &lt;2 years, 43% at 2 to &lt;4 years, 54% at 4 to &lt;6 years, 59% at 6 to &lt;8 years, 64% at 8 to &lt;10 years, and 67% at &gt;=10 years. Overall chronicity occurred in 25% of patients (95% CI: 23-29, n=170, mean follow-up: 59.3+/-71.2 months, no significant ED-group difference). The chronicity rate was 33% at &lt;2 years, 40% at 2 to &lt;4 years, 23% at 4 to &lt;6 years, 25% at 6 to &lt;8 years, 12% at 8 to &lt;10 years, and 18% at &gt;=10 years. Mortality occurred in 0.4% of patients (95% CI: 0.2-0.7, n=214, mean follow-up: 72.2+/-117.7 months, no significant ED-group difference). Considering observational studies, the mortality rate was 5.2 deaths/1,000 person-years (95% CI: 4.4-6.1, n=167, mean follow-up: 88.7+/-120.5 months; significant difference among EDs: p&lt;0.01, range: from 8.2 for mixed ED to 3.4 for BN). Hospitalization occurred in 26% of patients (95% CI: 18-36, n=18, mean follow-up: 43.2+/-41.6 months; significant difference among EDs: p&lt;0.001, range: from 32% for AN to 4% for BN). Regarding diagnostic migration, 8% of patients with AN migrated to BN and 16% to OSFED; 2% of patients with BN migrated to AN, 5% to BED, and 19% to OSFED; 9% of patients with BED migrated to BN and 19% to OSFED; 7% of patients with OSFED migrated to AN and 10% to BN. Children/adolescents had more favorable outcomes across and within EDs than adults. Self-injurious behaviors were associated with lower recovery rates in pooled EDs. A higher socio-demographic index moderated lower recovery and higher chronicity in AN across countries. Specific treatments associated with higher recovery rates were family-based therapy, cognitive-behavioral therapy (CBT), psychodynamic therapy, and nutritional interventions for AN; self-help, CBT, dialectical behavioral therapy (DBT), psychodynamic therapy, nutritional and pharmacological treatments for BN; CBT, nutritional and pharmacological interventions, and DBT for BED; and CBT and psychodynamic therapy for OSFED. In AN, pharmacological treatment was associated with lower recovery, and waiting list with higher mortality. These results should inform future research, clinical practice and health service organization for persons with EDs.
AN  - 38214616
AU  - Solmi,
AU  - M.
AU  - Monaco,
AU  - F.
AU  - Hojlund,
AU  - M.
AU  - Monteleone,
AU  - A.
AU  - M.
AU  - Trott,
AU  - M.
AU  - Firth,
AU  - J.
AU  - Carfagno,
AU  - M.
AU  - Eaton,
AU  - M.
AU  - De
AU  - Toffol,
AU  - M.
AU  - Vergine,
AU  - M.
AU  - Meneguzzo,
AU  - P.
AU  - Collantoni,
AU  - E.
AU  - Gallicchio,
AU  - D.
AU  - Stubbs,
AU  - B.
AU  - Girardi,
AU  - A.
AU  - Busetto,
AU  - P.
AU  - Favaro,
AU  - A.
AU  - Carvalho,
AU  - A.
AU  - F.
AU  - Steinhausen,
AU  - H.
AU  - C.
AU  - Correll,
AU  - C.
AU  - U.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/wps.21182
L1  - internal-pdf://0917670247/Solmi-2024-Outcomes in people with eating diso.pdf
PY  - 2024
SP  - 124-138
T2  - World Psychiatry
TI  - Outcomes in people with eating disorders: a transdiagnostic and disorder-specific systematic review, meta-analysis and multivariable meta-regression analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=38214616
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10785991/pdf/WPS-23-124.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - Purpose: This systematic review and meta-analysis aimed to investigate the overall effects of self-regulation interventions for children living in poverty. 

Methods: The initial search identified 473 publications of randomized controlled trials, including 25 that met the inclusion criteria. We used a random effect meta-analysis with robust variance estimation to calculate the overall and subgroup effects. Meta-regression was used to examine the moderating effects of intervention approach, outcome category, measurement approach, and participant age. 

Results: A small to medium but significant overall impact was found (g = 0.35, 95% confidence interval = [0.29, 0.41]). Behavioral interventions had the greatest overall effect and greatest subgroup effects on behavioral outcomes and emotional outcomes. Age and measurement approach were found to have significant moderating effects. 

Conclusions: Behavioral interventions should be put more attention to during the self-regulation intervention on children living in poverty. In addition, inducing the intervention for children at younger ages might be more efficient.
AN  - WOS:001327263900001
AU  - Wen,
AU  - H.
AU  - Cui,
AU  - J.
AU  - W.
AU  - Husile,
AU  - H.
DB  - November 2024.enl
DO  - 10.1177/10497315241284344
L1  - internal-pdf://1194755657/Wen-2024-Self-Regulation Interventions for Chi.pdf
PY  - 2024
SP  - 17
T2  - Research on Social Work Practice
TI  - Self-Regulation Interventions for Children in Living Poverty in the United States: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001327263900001
UR  - https://journals.sagepub.com/doi/10.1177/10497315241284344
UR  - https://journals.sagepub.com/doi/pdf/10.1177/10497315241284344?download=true
ER  -
TY  - JOUR
AB  - BAKGRUNN
Flyt er et livsmestringsprogram for elever på 10. trinn som har til hensikt å gjøre deltakere bedre rustet til å gjennomføre videregående skole. Programmet er et styrkebasert gruppetiltak for ungdom i risiko for å droppe ut fra videregående, men ungdom uten kjent risiko inkluderes også. For elever omfatter tiltaket totalt 80 timer med organiserte aktiviteter fordelt på helg- og kveldssamlinger, fra oktober i 10. klasse til september påfølgende år. Foreldre deltar på fire samlinger. Kronprinsparets Fond er tiltaksutviklere, eiere av tiltaket og står for opplæring av gruppeledere i programmet. Tiltaket gjennomføres lokalt i kommunen. Det første kullet til å prøve programmet gjennomførte i 2019, og i 2022&ndash;23 gjennomførtes det i 17 kommuner.

METODE
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

RESULTATER
Resultatene består av en vurdering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Flyt er godt beskrevet og bygger på et kjent teorigrunnlag. Det er gjennomført to norske evalueringer som har kartlagt brukererfaringer ved intervju, samt endring på noen variabler målt ved spørreskjema. Det foreligger ingen nordiske effektstudier av tiltaket.

KONKLUSJON
Flyt har en god teoretisk forankring og detaljerte beskrivelser av innhold og prosedyrer. Vi anbefaler å gjennomføre effektstudier som adresserer målsetningene eksplisitt med et tilstrekkelig stringent design.
Flyt klassifiseres på evidensnivå 2 &ndash; Teoretisk begrunnede tiltak.
AU  - Sagatun,
AU  - Å.,
AU  - Sæle,
AU  - R.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /post_tiltak_arkiv/flyt-1-utg/
L1  - internal-pdf://2221885244/Flyt-1-utg-1 (1).pdf
PY  - 2024
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Flyt (1. utg)
ER  -
TY  - JOUR
AB  - Huvudbudskap
Dialektisk beteendeterapi f&ouml;r ungdomar (DBT-A) f&ouml;rebygger återfall i sj&auml;lvskadebeteende. Internetf&ouml;rmedlad k&auml;nsloregleringsterapi (IERITA) kan f&ouml;rebygga nya episoder av icke-suicidalt sj&auml;lvskadebeteende.

Slutsatser
Efter att ha granskat den vetenskapliga litteraturen har SBU dragit f&ouml;ljande slutsatser:

DBT-A minskar antalet ungdomar med sj&auml;lvskadebeteende som får ett återfall. Behandlingen uppskattas av ungdomarna och deras f&ouml;r&auml;ldrar. DBT-A under fyra månader kan vara kostnadseffektivt j&auml;mf&ouml;rt med sedvanlig vård, men svenska h&auml;lsoekonomiska studier beh&ouml;vs.
IERITA som bygger på DBT-A kan m&ouml;jligen minska antalet ungdomar med icke-suicidalt sj&auml;lvskadebeteende som får ett återfall men h&auml;r beh&ouml;vs fler randomiserade studier som bekr&auml;ftar resultaten. I svenska studier &auml;r IERITA uppskattat av ungdomar, f&ouml;r&auml;ldrar och vården.
Ungdomar som identifierar sig som att tillh&ouml;ra en sexuell minoritet eller har ett riskfyllt substansbruk, eller &auml;r omh&auml;ndertagna i r&auml;ttssystemet, har en f&ouml;rh&ouml;jd risk f&ouml;r sj&auml;lvskadebeteende. Studier på f&ouml;rebyggande interventioner saknas eller &auml;r få och små.
Det beh&ouml;vs forskning om specifika behandlingar som &ouml;kar s&auml;kerheten kring en ungdom akut efter ett suicidf&ouml;rs&ouml;k. En s&auml;kerhetsplan, f&auml;rdighetstr&auml;ning och komponenter riktade till familjen verkar vara centralt, exempelvis familjeinterventionen SAFETY.
Det beh&ouml;vs effektiv heldygnsvård med mindre risk f&ouml;r långa vårdf&ouml;rlopp och f&ouml;rs&auml;mring av h&auml;lsotillståndet. Forskning med f&ouml;re-efterm&auml;tningar och kvalitativa studier pekar på v&auml;rdet av brukarstyrda inl&auml;ggningar men det beh&ouml;vs svenska randomiserade studier.
Vad skulle resultaten kunna inneb&auml;ra?
Resultaten tyder på att det finns en potential f&ouml;r att fler ungdomar med sj&auml;lvskadebeteende ska få tillgång till effektiva behandlingar. DBT-A &auml;r idag den enda metod som har vetenskapligt st&ouml;d f&ouml;r att minska risken f&ouml;r upprepade sj&auml;lvskadef&ouml;rs&ouml;k men erbjuds i huvudsak i storstadsregionerna. Behandlingen kan pågå i upp till ett år. Studierna visar dock att redan fyra månaders DBT-A &auml;r effektivt, något som skulle kunna frig&ouml;ra resurser f&ouml;r att behandla fler. F&ouml;r att inf&ouml;ra DBT-A på fler kliniker kommer det att kr&auml;vas omfattande utbildnings- och rekryteringsinsatser, sannolikt med f&ouml;rh&ouml;jda kostnader på kort sikt.

Vidare skulle IERITA kunna komplettera vårdutbudet f&ouml;r ungdomar med icke-suicidalt sj&auml;lvskadebeteende utan omedelbar suicidrisk. IERITA &auml;r inte lika etablerad som DBT-A och det kommer kr&auml;vas utbildningsinsatser.

Vad handlar rapporten om?
Sj&auml;lvskadebeteende, oavsett om avsikten &auml;r att avsluta sitt liv eller inte, hos barn och ungdomar &auml;r ett globalt h&auml;lsoproblem och suicid &auml;r den vanligaste d&ouml;dsorsaken f&ouml;r ungdomar. Sj&auml;lvskadebeteende &ouml;kar också risken f&ouml;r framtida suicidhandlingar, annan psykisk oh&auml;lsa, riskfyllt substansbruk och kriminalitet.

Syftet med rapporten var att utv&auml;rdera om det finns några interventioner som kan f&ouml;rebygga sj&auml;lvskadebeteende. Interventionerna skulle ges till barn och ungdomar som redan har ett sj&auml;lvskadebeteende eller till sådana som tillh&ouml;r några specifika riskgrupper.

Utv&auml;rderingen gjordes som en systematisk &ouml;versikt med metaanalyser, kompletterad med systematiska &ouml;versikter till grund f&ouml;r h&auml;lsoekonomiska och etiska aspekter. 

Vilka studier ligger till grund f&ouml;r resultaten?
Resultaten baseras på 28 randomiserade studier och en systematisk &ouml;versikt. Två h&auml;lsoekonomiska studier och elva studier med kvalitativ metodik ingår också i rapporten. Studierna har publicerats från år 1990 och framåt och de flesta har genomf&ouml;rts i USA och Storbritannien.

Samtliga studier utv&auml;rderade någon form av psykologisk behandling f&ouml;rutom en studie om brukarstyrda inl&auml;ggningar. Studier på l&auml;kemedel och andra t&auml;nkbara behandlingar saknades f&ouml;r ungdomar med sj&auml;lvskador eller suicidalt beteende.
AU  - SBU
DB  - Juli 2024.enl
DO  - /sv/publikationer/SBU-utvarderar/forebygga-sjalvskadebeteende-och-suicidforsok-hos-barn-och-ungdomar--effekter-av-riktade-interventioner/
L1  - internal-pdf://3042164734/forebygga-sjalvskadebeteende-och-suicidforsok-.pdf
PY  - 2024
T2  - Statens beredning f&ouml;r medicinsk och social utv&auml;rdering (SBU)
TI  - F&ouml;rebygga sj&auml;lvskadebeteende och suicidf&ouml;rs&ouml;k hos barn och ungdomar &ndash; effekter av riktade interventioner
ER  -
TY  - JOUR
AB  - **Background:** 
Self-management interventions (SMI) are a broad class of interventions used to teach students to assess, monitor, and adjust their own behavior without direct intervention from an educator. SMI support students with autism spectrum disorder (ASD) to learn valuable selfawareness and self-determination skills for better outcomes in adulthood. 

**Methods:** 
A systematic review and meta-analysis were employed to examine the students with ASD who are likely to benefit from SMIs in educational settings, the conditions these interventions are effective under, and identify the discrete intervention packages, social validity, and anticipated effects of the intervention. 

**Results:** 
This review examined 62 single case designs with adequate quality and rigor in 18 studies, including 34 cases and 53 students with ASD. Findings indicating limited participant and intervention condition reporting within the evidence-base. 

**Conclusions:** 
Lack of translational reporting of ASD characteristics, implementation conditions, and training methods limited conclusions about for whom and under what conditions. Further, the majority of studies in the evidence base focused exclusively on self-monitoring interventions to address engagement behaviors, indicating a need for further examination of other selfmanagement components. Future directions of translational research of SMI for students with ASD are discussed.
AN  - WOS:001134413000001
AU  - Scheibel,
AU  - G.
AU  - Zaeske,
AU  - L.
AU  - M.
AU  - Malone,
AU  - E.
AU  - J.
AU  - Zimmerman,
AU  - K.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.rasd.2023.102294
L1  - internal-pdf://1461946227/1-s2.0-S1750946723001940-main.cleaned.pdf
PY  - 2024
SP  - 18
T2  - Research in Autism Spectrum Disorders
TI  - A meta-analysis of self-management interventions for students with ASD
UR  - &lt;Go to ISI&gt;://WOS:001134413000001
UR  - https://www.sciencedirect.com/science/article/pii/S1750946723001940?via%3Dihub
VL  - 110
ER  -
TY  - JOUR
AB  - Importance: Pediatric posttraumatic stress disorder (PTSD) is a common and debilitating mental disorder, yet a comprehensive network meta-analysis examining psychological interventions is lacking. 

Objective: To synthesize all available evidence on psychological interventions for pediatric PTSD in a comprehensive systematic review and network meta-analysis. 

Data Sources: PsycINFO, MEDLINE, Web of Science, and PTSDpubs were searched from inception to January 2, 2024, and 74 related systematic reviews were screened. 

Study Selection: Two independent raters screened publications for eligibility. Inclusion criteria were randomized clinical trial (RCT) with at least 10 patients per arm examining a psychological intervention for pediatric PTSD compared to a control group in children and adolescents (19 years and younger) with full or subthreshold PTSD. 

Data Extraction and Synthesis: PRISMA guidelines were followed to synthesize and present evidence. Two independent raters extracted data and assessed risk of bias with Cochrane criteria. Random-effects network meta-analyses were run. <b>Main Outcome and Measures</b>: Standardized mean differences (Hedges g) in PTSD severity. <b>Results</b>: In total, 70 RCTs (N = 5528 patients) were included. Most RCTs (n = 52 [74%]) examined trauma-focused cognitive behavior therapies (TF-CBTs). At treatment end point, TF-CBTs (g, 1.06; 95% CI, 0.86-1.26; P &lt; .001), eye movement desensitization and reprocessing (EMDR; g, 0.86; 95% CI, 0.54-1.18; P &lt; .001), multidisciplinary treatments (MDTs) (g, 0.88; 95% CI, 0.53-1.23; P &lt; .001), and non-trauma-focused interventions (g, 0.95; 95% CI, 0.62-1.28; P &lt; .001) were all associated with significantly larger reductions in pediatric PTSD than passive control conditions. TF-CBTs were associated with the largest short-term reductions in pediatric PTSD relative to both passive and active control conditions and across all sensitivity analyses. In a sensitivity analysis including only trials with parent involvement, TF-CBTs were associated with significantly larger reductions in pediatric PTSD than non-trauma-focused interventions (g, 0.35; 95% CI, 0.04-0.66; P = .03). Results for midterm (up to 5 months posttreatment) and long-term data (6-24 months posttreatment) were similar. 

Conclusions and Relevance: Results from this systematic review and network meta-analysis indicate that TF-CBTs were associated with significant reductions in pediatric PTSD in the short, mid, and long term. More long-term data are needed for EMDR, MDTs, and non-trauma-focused interventions. Results of TF-CBTs are encouraging, and disseminating these results may help reduce common treatment barriers by counteracting common misconceptions, such as the notion that TF-CBTs are harmful rather than helpful.
AN  - 39630422
AU  - Hoppen,
AU  - T.
AU  - H.
AU  - Wessarges,
AU  - L.
AU  - Jehn,
AU  - M.
AU  - Mutz,
AU  - J.
AU  - Kip,
AU  - A.
AU  - Schlechter,
AU  - P.
AU  - Meiser-Stedman,
AU  - R.
AU  - Morina,
AU  - N.
DB  - Desember 2024.enl
DO  - /10.1001/jamapsychiatry.2024.3908
L1  - internal-pdf://1019214495/e0e2aa6b-c417-4ea6-8270-8f1aa9074983.pdf
PY  - 2024
SP  - 04
T2  - JAMA Psychiatry
TI  - Psychological Interventions for Pediatric Posttraumatic Stress Disorder: A Systematic Review and Network Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1001%2fjamapsychiatry.2024.3908
UR  - https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2827463
VL  - 04
ER  -
TY  - JOUR
AB  - Background 
Attention deficit/hyperactivity disorder (ADHD) affects the physical and mental health in children and adolescents. Evidence suggests that participation in exercise may benefit children and adolescents with ADHD and enhance current and future physical and mental health. This systematic review and meta-analysis investigated the effects of exercise interventions on the physical and mental health of children and adolescents with ADHD, based on the International Classification of Functioning, Disability and Health-Children and Youth Version (ICF-CY) framework. 

Method 
This review systematically searched for studies published up to August 1, 2023, through PubMed, Web of Science, PsycINFO, and Scopus. A meta-analysis was performed on studies that reported physical and mental health outcomes more than 10 times. A semiquantitative analysis was performed on studies that reported those indicators less than 10 times. In addition, all physical and mental health outcome indicators were linked to ICF-CY codes. 

Results 
A total of 43 studies were included in the systematic review, 13 of which were eligible for meta-analysis. Our meta-analysis results showed that levels of anxiety and depression significantly decreased after exercise intervention, with medium (Hedges&#039;g = - 0.63, 95% CI [1.17, - 0.09], P &lt; 0.05) and large effect sizes (Hedges&#039;g = - 1.03, 95% CI [- 1.94, - 0.12], P &lt; 0.05), respectively. The level of attention problem significantly decreased after exercise intervention, with a large effect size (Hedges&#039;g = - 1.28, 95% CI [- 2.59, 0.04], P = 0.06), but no statistical difference was observed. The level of motor skills significantly improved after exercise intervention with a large effect size (Hedges&#039;g = 0.97, 95% CI [0.42, 1.51], P &lt; 0.01). The level of muscle strength significantly improved after exercise intervention, with a small effect size (Hedges&#039;g = 0.37, 95% CI [0.05, 0.68], P &lt; 0.05). The included studies covered a total of 31 outcome indicators, which could be divided into 4 one-level classifications and 27 two-level classifications according to the ICF-CY framework. Among the outcome indicators, 21 (67.74%) were related to &quot;physical functions&quot;, 9 (29.03%) were related to &quot;activities and participation&quot;, and 1 (3.23%) was related to &quot;body structures&quot;. 

Conclusion 
This study confirmed that exercise could improve the physical and mental health in children and adolescents with ADHD. Regarding exercise intervention to improve the health of children and adolescents with ADHD, existing research has focused on verifying the immediate effect of intervention from the perspective of &quot;physical functions&quot;. However, there is a lack of in-depth exploration into changes in the dimensions of &quot;body structures&quot; and &quot;activities and participation&quot;, as well as the long-term intervention effects. Future studies should focus more on a holistic view of health that considers &quot;body structures and functions&quot; and &quot;activities and participation&quot;, which could ultimately favor comprehensive and long-term improvements in the health status of children and adolescents with ADHD.
AN  - WOS:001288233200004
AU  - Feng,
AU  - L.
AU  - L.
AU  - Li,
AU  - B.
AU  - W.
AU  - Yong,
AU  - S.
AU  - S.
AU  - Tian,
AU  - Z.
AU  - J.
DB  - September 2024.enl
DO  - 10.1007/s42978-024-00295-8
L1  - internal-pdf://1559583130/s42978-024-00295-8.cleaned.pdf
PY  - 2024
SP  - 18
T2  - Journal of Science in Sport and Exercise
TI  - Effects of Exercise Intervention on Physical and Mental Health of Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-analysis Based on ICF-CY
UR  - &lt;Go to ISI&gt;://WOS:001288233200004
UR  - https://link.springer.com/article/10.1007/s42978-024-00295-8
ER  -
TY  - JOUR
AB  - Brief, school-based mental health interventions hold promise for reducing barriers to mental health support access, a critical endeavor in light of increasing rates of mental health concerns among youth. However, there is no consensus on whether or not brief school-based interventions are effective at reducing mental health concerns or improving well-being. This systematic review and meta-analysis aims to provide consensus and determine directions for future work. Articles were included if they examined a brief (&lt;= four sessions or 240 min of intervention time) psychosocial intervention, were conducted within a Pre-K through 12th-grade school setting, included at least one treatment outcome evaluating mental health or well-being, and were published since 2000. A total of 6,702 papers were identified through database searching, of which 81 papers (k studies = 75) were ultimately selected for inclusion. A total of 40,498 students were included across studies and a total of 75 unique interventions were examined. A total of 324 effect sizes were extracted. On average, interventions led to statistically significant improvements in mental health/well-being outcomes versus control conditions up to one-month (g = .18, p = .004), six-month (g = .15, p = .006), and one-year (g = .10, p = .03) post-intervention. There may be benefits to brief school-based interventions from a preventative public health standpoint; future research may focus on how to optimize their real-world utility. Prospero pre-registration: CRD42021255079.
AN  - 38884838
AU  - Cohen,
AU  - K.
AU  - A.
AU  - Ito,
AU  - S.
AU  - Ahuvia,
AU  - I.
AU  - L.
AU  - Yang,
AU  - Y.
AU  - Zhang,
AU  - Y.
AU  - Renshaw,
AU  - T.
AU  - L.
AU  - Larson,
AU  - M.
AU  - Cook,
AU  - C.
AU  - Hill,
AU  - S.
AU  - Liao,
AU  - J.
AU  - Rapoport,
AU  - A.
AU  - Smock,
AU  - A.
AU  - Yang,
AU  - M.
AU  - Schleider,
AU  - J.
AU  - L.
DB  - Juni 24.enl
DO  - /10.1007/s10567-024-00487-2
L1  - internal-pdf://3065146618/Cohen-2024-Brief School-Based Interventions Ta.pdf
PY  - 2024
SP  - 17
T2  - Clinical Child &amp; Family Psychology Review
TI  - Brief School-Based Interventions Targeting Student Mental Health or Well-Being: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs10567-024-00487-2
UR  - https://link.springer.com/article/10.1007/s10567-024-00487-2
UR  - https://link.springer.com/content/pdf/10.1007/s10567-024-00487-2.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - Background
High rates of youth re-offending indicate that young custody-leavers face challenges when reintegrating into their communities. Aftercare and resettlement programs can occur pre-, during, and post-release and generally provide multiple forms of support services to address youths&#039; transitional needs.

Objectives
The present review examines (1) the impact of youth aftercare/resettlement programs on crime-related outcomes, (2) how treatment effect is moderated by participant, program, and study characteristics, (3) whether some types of interventions are more effective than others, (4) barriers/facilitators to effective program implementation, (5) the theory of change underlying resettlement interventions, and (6) available research on intervention cost.

Search Methods
A comprehensive set of keywords and synonyms was combined in a Boolean search across 26 electronic databases. Multiple gray literature sources were also searched, including 23 journals, 4 meeting archives, 11 organization websites, 3 open access journal websites, and the CVs of 8 well-known researchers in the field. The search was completed in January 2023.

Selection Criteria
For objectives 1&ndash;3, studies were included if they utilized a randomized controlled design or quasi-experimental comparison group design in which participants were matched on at least some baseline variables and included at least one quantitative individual-measure of crime. For objective 4, included studies presented process evaluations of aftercare/reentry programs, clearly stated their research goals, and used qualitative methods in an appropriate way to answer the stated research question. For objectives 5 and 6, no specific methods were required; any study meeting the criteria for objectives 1&ndash;4 which presented findings on theory of change or cost data were included. For all outcomes, only studies conducted in a westernized country, and published after 1991 in English, French, or German were considered.

Data Collection and Analysis
Two coders conducted primary data extraction for the included studies. Data were entered into a Microsoft Excel database. After data extraction, the two coders validated the coding by cross-checking the database with each research report. Discrepancies between coders were discussed until consensus was reached. Where consensus could not be reached, a third coder was consulted. Study risk of bias was addressed using the ROBINS-I (Sterne et al., 2016), ROB-2 (Higgins et al., 2019), and the critical appraisal skills programme (CASP, 2018). Objectives 1&ndash;3 were addressed by synthesizing quantitative outcomes from rigorous impact evaluations of aftercare interventions using random effects models and meta-regression. Thematic and narrative analysis was conducted to address objectives 4&ndash;6.

Results
The search resulted in 15 impact studies, representing 4,718 participants across 21 program sites, and 35 effect sizes. The 21 impact evaluations were rated as having either low/moderate bias (k&thinsp;=&thinsp;11) or serious bias (k&thinsp;=&thinsp;10). The synthesis of 15 impact studies found no significant effects for arrest (k&thinsp;=&thinsp;14; OR&thinsp;=&thinsp;1.044, 95% prediction interval [0.527, 2.075], t&thinsp;=&thinsp;0.335) or incarceration (k&thinsp;=&thinsp;8, OR&thinsp;=&thinsp;0.806, 95% prediction interval [2.203, 1.433], t&thinsp;=&thinsp;&minus;1.674). A significant pooled effect was found for conviction (k&thinsp;=&thinsp;13, OR&thinsp;=&thinsp;1.209, 95% prediction interval [1.000, 1.462], t&thinsp;=&thinsp;2.256), but results were highly sensitive to the inclusion of specific studies. No meaningful pattern of results emerged in moderator analyses with respect to study, sample, program component, or program delivery characteristics. The 19 process studies were rated as either high quality (k&thinsp;=&thinsp;12) or moderate quality (k&thinsp;=&thinsp;7). Thematic synthesis of the process evaluations revealed 15 themes related to the strengths/challenges of program implementation. The assessment of program cost (k&thinsp;=&thinsp;7) determined a lack of data within the literature, preventing any summative analysis.

Authors&#039; Conclusions
Current evidence is promising with respect to conviction outcomes but overall does not find that aftercare/resettlement interventions have a reliably positive impact on crime-related outcomes for young people who have offended. High variability across outcomes and reported data resulted in small sample sizes per outcome and limited moderator analyses. Multiple challenges for program implementation exist; additional rigorous research is sorely needed to further investigate the nuances of the program effects.
AU  - Wong,
AU  - J.
AU  - S.,
AU  - Lee,
AU  - C.,
AU  - Beck,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1002/cl2.1404
L1  - internal-pdf://1885694873/Campbell Systematic Reviews - 2024 - Wong - Th.pdf
PY  - 2024
T2  - Campbell Systematic Reviews
TI  - The effects of aftercare/resettlement services on crime and violence in children and youth: A systematic review
ER  -
TY  - JOUR
AB  - **Huvudbudskap**
Forskning visar att program f&ouml;r socioemotionellt l&auml;rande (SEL) st&auml;rker de f&ouml;rmågor hos barn och ungdomar som fr&auml;mjar psykiskt v&auml;lbefinnande. Detta g&auml;ller oavsett ålder, k&ouml;n, socioekonomisk status och grad av psykiskt v&auml;lbefinnande innan insatsen påb&ouml;rjades.

**Slutsatser**
Efter att ha granskat den vetenskapliga litteraturen har SBU dragit f&ouml;ljande slutsatser:

SEL-program har medelstora eller små positiva effekter på f&ouml;rmågor som st&ouml;djer psykiskt v&auml;lbefinnande, såsom sj&auml;lvkontroll, social medvetenhet, relationskompetens, resiliens och copingstrategier.
Resultaten g&auml;ller oavsett ålder, k&ouml;n och socioekonomisk status.
Barn med l&auml;gre grad av psykiskt v&auml;lbefinnande tycks gynnas mer av SEL-program &auml;n andra barn, men det vetenskapliga underlaget &auml;r begr&auml;nsat.
F&ouml;r barn och ungdomar i åldern 12 till 18 år kan programmen &auml;ven ha positiva effekter på det psykiska v&auml;lbefinnandet. F&ouml;r yngre barn går det inte att bed&ouml;ma SEL-programmens effekter på det psykiska v&auml;lbefinnandet, eftersom det finns f&ouml;r lite forskning.
Hur kan de viktigaste resultaten f&ouml;rstås?
Alla barn och ungdomar har r&auml;tt till psykiskt v&auml;lbefinnande. Bristande psykiskt v&auml;lbefinnande kan bland annat påverka barns skolprestationer negativt och ofullst&auml;ndiga betyg från grundskolan &ouml;kar risken f&ouml;r framtida psykosociala problem. SEL-program f&ouml;rmedlade till alla barn och ungdomar via f&ouml;rskola och skola skulle kunna &ouml;ka m&ouml;jligheten f&ouml;r fler att bibehålla eller f&ouml;rb&auml;ttra sina f&ouml;rmågor till psykiskt v&auml;lbefinnande. Vi kan inte påvisa några negativa effekter av SEL-programmen. De flesta av studierna &auml;r genomf&ouml;rda i l&auml;nder utanf&ouml;r Norden och det skulle vara v&auml;rdefullt att unders&ouml;ka vilka program som anv&auml;nds i svensk f&ouml;rskola och skola.

**Vad handlar rapporten om?**
SEL-program syftar till att st&auml;rka socioemotionella f&auml;rdigheter som i sin tur kan bidra till b&auml;ttre psykiskt v&auml;lbefinnande. Syftet var att f&ouml;lja upp en tidigare SBU-rapport [1] genom att unders&ouml;ka effekterna av socioemotionellt l&auml;rande, f&ouml;rmedlat genom SEL-program, med avseende på barns ålder, k&ouml;n, socioekonomisk status och grad av psykiskt v&auml;lbefinnande innan insatsen påb&ouml;rjades. Programmen gavs i f&ouml;rskolor och skolor och hade en universell ansats, det vill s&auml;ga gavs till samtliga barn i klasserna.

**Vilka studier ligger till grund f&ouml;r resultaten?**
Totalt inkluderades 69 studier (48 från huvudrapporten och 21 från uppdateringss&ouml;kningen) i rapporten, N = 98 178. Den senaste litteraturs&ouml;kningen gjordes i mars 2023. Samtliga studier unders&ouml;kte effekterna av SEL-program på barns och ungdomars (0&ndash;18 år) upplevda psykiska v&auml;lbefinnande (3 utfall) och f&ouml;rmågor till detsamma (9 utfall). Programmen j&auml;mf&ouml;rdes fr&auml;mst med sedvanlig undervisning. Studier från samtliga v&auml;rldsdelar fanns med i underlaget.
AU  - SBU
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /sv/publikationer/SBU-utvarderar/framjande-av-psykiskt-valbefinnande-hos-barn-och-ungdomar2/
L1  - internal-pdf://0242306015/framjande-av-psykiskt-valbefinnande-hos-barn-o.pdf
PY  - 2024
T2  - SBU
TI  - Fr&auml;mjande av psykiskt v&auml;lbefinnande hos barn och ungdomar
ER  -
TY  - JOUR
AB  - BACKGROUND: Intensive Family Preservation Services (IFPS) are an important part of child welfare. They are short-term, in-home treatment programs aimed at preventing imminent out-of-home placements, however, today, their overall effectiveness remains unclear. 

OBJECTIVE: This study aims to conduct a comprehensive review of IFPS effectiveness, evaluate a wide range of outcomes, and analyze the impact of various factors on its success. 

METHODS: A three-level meta-analysis was conducted on 33 controlled trial studies comprising 226 effect sizes to test whether the effectiveness of IFPS was influenced by study, program, target, sample, and outcome characteristics.

RESULTS: Analyses showed that IFPS did have a modest overall effect on treatment outcomes (g = 0.18), with notable variations across different outcome measures, showing small and positive effects on out-of-home placement (g = 0.31), family functioning (g = 0.19), juvenile delinquency (g = 0.19), and parental psychopathology (g = 0.34). Greater program intensity was associated with smaller effects, and follow-up assessment yielded larger effects than post-test assessments, indicating that positive intervention effects increased over time. 

CONCLUSIONS: The findings suggest a rather limited effectiveness of IFPS, indicating that both practice and policy should take this into account. Recommendations for future research are provided to further enhance understanding and improvement of IFPS interventions.
AN  - 39675057
AU  - Lippens,
AU  - L.
AU  - De
AU  - Clercq,
AU  - L.
AU  - Vandevelde,
AU  - S.
AU  - De
AU  - Pauw,
AU  - S.
AU  - Stams,
AU  - G.
AU  - J.
DB  - Desember 2024.enl
DO  - /10.1016/j.chiabu.2024.107198
L1  - internal-pdf://2860972421/87b7ecdc-50aa-4439-9b5b-1cd124aa2b9e.pdf
PY  - 2024
SP  - 107198
T2  - Child Abuse &amp; Neglect
TI  - Evaluating the effectiveness of intensive family preservation services: A multi-level meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.chiabu.2024.107198
UR  - https://www.sciencedirect.com/science/article/pii/S014521342400591X?via%3Dihub
VL  - 160
ER  -
TY  - JOUR
AB  - **Purpose of Review**
This narrative review summarizes research-to-date on strategies to prevent problematic cannabis use.

**Recent Findings**
Ten meta-analytic reviews of cannabis use prevention strategies published after 2010 were identified for this review. The meta-analytic reviews were based on studies evaluating the effectiveness of school-based programs, online/digital interventions, mass-media approaches, culturally specific interventions, and brief interventions. Results indicate that school-based programs, online/digital interventions, and culturally specific interventions may help to prevent or reduce cannabis use, though effect sizes were modest. Brief interventions were found to have no effect on cannabis use frequency, but had small beneficial effects on cannabis use disorder, consequences, and abstinence. Mass media approaches were not effective in preventing cannabis use.

**Summary**
School-based programs, online/digital interventions, culturally specific interventions, and brief interventions can have modest effects on problematic cannabis use. Research is needed to evaluate environmental strategies to prevent problematic cannabis use at the population level.
AN  - WOS:001275426500001
AU  - O&#039;Hara,
AU  - S.
AU  - E.
AU  - Paschall,
AU  - M.
AU  - J.
AU  - Grube,
AU  - J.
AU  - W.
DB  - August 2024.enl
DO  - 10.1007/s40429-024-00592-w
L1  - internal-pdf://1550080832/O&#039;Hara-2024-A Review of Meta-Analyses of Preve.pdf
PY  - 2024
SP  - 886-893
T2  - Current Addiction Reports
TI  - A Review of Meta-Analyses of Prevention Strategies for Problematic Cannabis Use
UR  - &lt;Go to ISI&gt;://WOS:001275426500001
UR  - https://link.springer.com/article/10.1007/s40429-024-00592-w
UR  - https://link.springer.com/content/pdf/10.1007/s40429-024-00592-w.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - The majority of studies in the current literature analyse cyberbullying at the secondary education stage. Nevertheless, although it has been shown that cybervictim and cyberbully roles may arise from the Primary School stage onwards, more research is still needed. The consequences of this problem can be manifested in indicators of psycho-social and psycho-emotional adjustment, harming not only the aggressor and the victim, but also the bystander. The aim of this study is to deepen the research and to analyse cyberbullying programmes implemented in primary schools in order to know their results and what are those factors on which the programmes are focused. Thus, a systematic and exhaustive search for empirical studies was carried out, with 17 programmes included in the review. It has been observed that cyberbullying prevention interventions from the first contact with technologies are effective in addressing and reducing cyberbullying-related behaviours. Specifically, emotional competence, self-regulation skills, school climate and online safety are factors that are present in programmes with positive results in prevention of cyberbullying. Furthermore, the need to design and validate specific data collection instruments for Primary Education is highlighted, as well as it is necessary to increase the frequency of implementation and evaluation of interventions, favouring collaboration between families and the educational centre.
AN  - WOS:001217021900001
AU  - Chicote-Beato,
AU  - M.
AU  - Gonz&aacute;lez-V&iacute;llora,
AU  - S.
AU  - Bodoque-Osma,
AU  - A.
AU  - R.
AU  - Navarro,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1016/j.avb.2024.101938
L1  - internal-pdf://0111106815/1-s2.0-S1359178924000284-main.cleaned.pdf
PY  - 2024
SP  - 15
T2  - Aggression and Violent Behavior
TI  - Cyberbullying intervention and prevention programmes in Primary Education (6 to 12 years): A systematic review
UR  - &lt;Go to ISI&gt;://WOS:001217021900001
UR  - https://www.sciencedirect.com/science/article/pii/S1359178924000284?via%3Dihub
VL  - 77
ER  -
TY  - JOUR
AB  - Parenting support to enhance parent and child mental health is increasingly offered on websites, apps, and through videocall. This development raises the question of how online parenting support compares to traditional in -person parenting support. Is online support non-inferior to traditional in -person support? Or should online support be used as a supplement to in -person support? In the COST Action EurofamNet (CA18123), we sought to answer these questions by systematically searching for randomized trials comparing online to in -person parenting support (Study 1) and trials comparing in -person parenting support augmented with online support elements to in -person parenting support only (Study 2). We registered our review in PROSPERO (CRD42022354393) and searched PsycINFO, MEDLINE, Web of Science, and Cochrane in May 2022. Our outcomes of interests were children&#039;s mental health, parenting practices, parental mental health, and parents&#039; satisfaction with the program. For Study 1, multilevel meta-analysis of seven eligible randomized trials (101 effect sizes; N = 957) showed consistent non-inferiority of online support and a trend that parents were more satisfied with online support. For Study 2, narrative synthesis of two eligible trials (N = 279) suggests that adding online support elements to in -person support can improve program satisfaction and short -term benefits, but does not contribute significantly to program benefits above and beyond in -person support. Our findings suggest that, provided appropriate online formats and sufficient guidance from professionals, online parenting support is noninferior to in -person support. The additive value of online support elements to in -person support seems limited, but may still be meaningful. Future research should identify the circumstances under which parents prefer, and benefit more from, in -person versus online parenting support.
AN  - WOS:001193942500001
AU  - Leijten,
AU  - P.
AU  - Rienks,
AU  - K.
AU  - Groenman,
AU  - A.
AU  - P.
AU  - Anand,
AU  - M.
AU  - Akik,
AU  - B.
AU  - K.
AU  - David,
AU  - O.
AU  - Kiziltepe,
AU  - R.
AU  - Thongseiratch,
AU  - T.
AU  - Can&aacute;rio,
AU  - A.
AU  - C.
DB  - April 24.enl
DO  - 10.1016/j.childyouth.2024.107497
L1  - internal-pdf://0938654950/1-s2.0-S0190740924000690-main.cleaned.pdf
PY  - 2024
SP  - 10
T2  - Children and Youth Services Review
TI  - Online parenting support: Meta-analyses of non-inferiority and additional value to in-person support
UR  - &lt;Go to ISI&gt;://WOS:001193942500001
UR  - https://www.sciencedirect.com/science/article/pii/S0190740924000690?via%3Dihub
VL  - 159
ER  -
TY  - JOUR
AB  - This study aimed to compare and rank the effectiveness of optimal exercise intensity in improving executive function in patients with ADHD (Attention deficit hyperactivity disorder, ADHD) through a comprehensive comparison of direct and indirect evidence. A systematic search was performed in five electronic databases to explore the optimal exercise intensity for improving executive function in patients with ADHD by directly and indirectly comparing a variety of exercise intervention intensities. In addition, the isolated effects of exercise on improving executive function in patients with ADHD were explored through classical meta-analysis of paired direct comparisons. Twenty-nine studies were retrieved and included in this study. Classical paired meta-analysis showed that for the patients with ADHD in the age group of 7-17 years, statistical difference was observed for all the parameters of exercise interventions (intensity, frequency, period, and training method), the three dimensions of executive function, the use of medication or not, the high and low quality of the methodological approach. Network meta-analysis showed that high-intensity exercise training was optimal for improving working memory (97.4%) and inhibitory function (85.7%) in patients with ADHD. Meanwhile, moderate-intensity exercise training was optimal for improving cognitive flexibility (77.3%) in patients with ADHD. Moderate to high intensity exercise training shows potential for improving executive function in these patients. Therefore, we recommend applying high-intensity exercise intervention to improve executive function in patients with ADHD to achieve substantial improvement.
AN  - 38922348
AU  - Chen,
AU  - J.
AU  - W.
AU  - Du,
AU  - W.
AU  - Q.
AU  - Zhu,
AU  - K.
DB  - Juni 24.enl
DO  - /10.1007/s00787-024-02507-6
L1  - internal-pdf://4199968103/Chen-2024-Optimal exercise intensity for impro.pdf
PY  - 2024
SP  - 26
T2  - European Child &amp; Adolescent Psychiatry
TI  - Optimal exercise intensity for improving executive function in patients with attention deficit hyperactivity disorder: systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs00787-024-02507-6
UR  - https://link.springer.com/article/10.1007/s00787-024-02507-6
UR  - https://link.springer.com/content/pdf/10.1007/s00787-024-02507-6.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - Background
Parental substance misuse is a pervasive risk factor for a range of detrimental outcomes for children across the life course. While a variety of interventions have been developed for this population, the existing evidence-base requires consolidation and consideration of the comparative effectiveness of different interventions to facilitate evidence-informed decisions between different intervention approaches.

Objectives
This review aimed to use network meta-analysis to synthesise the comparative effectiveness of psychosocial, legal, and pharmacological interventions for improving outcomes for children with substance misusing parents. Network meta-analysis was not possible; however, we synthesised the effects of a broad range of interventions on child psychosocial outcomes. Another aim was to examine potential moderators of the effects, yet this was also not possible due to data limitations. A secondary objective was to qualitatively synthesise economic, treatment completion, and treatment acceptability information for included studies.

Search Methods
Searches were performed in November 2020 and again in April 2021. Encompassing multiple disciplines, we searched 34 databases, 58 grey literature repositories, and 10 trial registers. Supplementary hand searches were conducted on 11 journals, along with harvesting the references of all included studies and existing reviews, and forward citation searching each report of all included studies. Study authors were contacted to obtain missing data.

Selection Criteria
Eligible studies included randomised and quasi-experimental evaluations of psychosocial, pharmacological, and/or legal interventions using either a placebo, no treatment, waitlist control, treatment-as-usual, or alternative treatment as a comparison condition. Study participants needed to be comprised of families with children under the age of 18 with one or more currently substance-misusing parents (or caregivers). Studies were required to evaluate the eligible intervention using a child-focused psychosocial outcome. If reported in eligible studies, the following secondary outcomes were also synthesised in the review: cost-effectiveness, treatment completion, length of time in treatment and acceptability of treatment (e.g., participant perspectives of the intervention). There were no restrictions placed on publication status or geographic location, however only research written in English was included.

Data Collection and Analysis
Standard methodological procedures were followed across all stages of the review, as guided by the published protocol for the review (Eggins et al., 2020). Due to the inability to conduct network meta-analyses, random effects pairwise meta-analyses with inverse variance were used to synthesise effects when two or more studies with conceptually similar interventions and outcomes were available. Results of the meta-analyses are displayed in forest plots, and separate analyses are provided for conceptually distinct outcomes and time-points of measurement. Sensitivity analyses are used to explore possible sources of heterogeneity in the absence of sufficient studies to conduct subgroup analyses.

Main Results
99 studies (reported in 231 documents) met review inclusion criteria, encompassing 22,213 participants. Most studies were conducted in the United States (k&thinsp;=&thinsp;76), almost half were randomised controlled trials (k&thinsp;=&thinsp;46), and the most common comparator was treatment-as-usual (k&thinsp;=&thinsp;50). Interventions were evaluated using a large range of child psychosocial outcomes which broadly fell under: (a) child welfare; (b) child development; (c) child emotional and behavioural; and (d) educational domains. Intervention models were rarely only legal or pharmacological in nature, with most studies evaluating integrated psychosocial treatments with either pharmacology, coordinated health care, case-management, and/or judicial or child welfare oversight and coordination. Thirty-six meta-analyses and 227 single effect sizes were used to appraise the effectiveness of included interventions, based on 68 studies with sufficient data for effect size calculation. The size and direction of the effects varied across interventions, type of outcomes, and time-point of measurement. Twenty-seven meta-analyses and 186 single effect sizes suggested null effects. Only five single effect size estimates based on three studies indicated negative effects including: higher depressive and somatisation symptoms (parent-report), hopelessness (child-report), educational achievement difficulties (parent-report), and substantiated child protection reports for those engaged with interventions versus treatment-as-usual or no treatment. Nine meta-analyses and 36 single study effect estimates suggest that psychosocial, pharmacological and/or legal interventions have a positive effect on a range of specific child welfare, developmental, and emotional/behavioural outcomes for children. The risk of bias varied across domains and studies, which further lowers confidence in the results. Based on a subset of included studies, treatment completion tends to vary, yet cost-benefits can be achieved when intervening with children whose parents misuse substances.

Authors&#039; Conclusions
Despite a large body of evaluation evidence, disparate outcomes, and missing data precluded analyses to formally examine the comparative effectiveness of psychosocial, legal, and pharmacological interventions for improving outcomes for children with substance misusing parents. The large amount of unreported (missing) data meant that many effect estimates were underpowered due to single studies and small sample sizes. The review findings suggest that interventions for families affected by parental substance misuse can be effective when they holistically address multiple domains such as parent wellbeing/mental health, parenting, children&#039;s wellbeing, and/or other factors impacting family wellbeing (e.g., housing).
AU  - Eggins,
AU  - Elizabeth
AU  - Wilson,
AU  - David
AU  - B.
AU  - Betts,
AU  - Joseph
AU  - Roetman,
AU  - Sara
AU  - Chandler-Mather,
AU  - Ned
AU  - Theroux,
AU  - Bronwyn
AU  - Dawe,
AU  - Sharon
DB  - September 2024.enl
DO  - /10.1002/cl2.1413
L1  - internal-pdf://0908126372/Eggins - Psychosocial pharmacological and le.pdf
PY  - 2024
SP  - e1413
T2  - Campbell Systematic Reviews
TI  - Psychosocial, pharmacological, and legal interventions for improving the psychosocial outcomes of children with substance misusing parents: A systematic review
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/cl2.1413
VL  - 20
ER  -
TY  - JOUR
AB  - Motivational Interviewing (MI) is a brief counseling intervention with demonstrated efficacy in ameliorating unhealthy habits across populations, behaviors, and settings. Although prior research underscores its benefit with adolescents, a comprehensive examination of its application in school settings remains unexplored. Therefore, the primary aim of the present meta-analysis was to calculate the average estimated effect of all studies examining the use of MI with students in school settings. Second, we sought to examine heterogeneity in effects through meta- regression models. Our final model included a meta-analysis of 38 studies with 207 effect sizes evaluating the efficacy of school-based MI. We estimated multivariate models using robust variance estimation with and without outliers. Our results demonstrate a significant estimated effect in favor of using MI to treat an array of behaviors (g = 0.18, 95% Prediction Interval [-0.26, 0.61]). Findings from the meta-regression analyses indicated three significant moderators: (a) the role of the interventionist, (b) target behaviors, and (c) dosage. We offer potential explanations of the findings and discuss current limitations and implications for future work regarding MI in school settings.
AN  - WOS:001345418500001
AU  - Gersib,
AU  - J.
AU  - A.
AU  - Rojo,
AU  - M.
AU  - King,
AU  - S.
AU  - G.
AU  - Doabler,
AU  - C.
AU  - T.
DB  - November 2024.enl
DO  - 10.1016/j.jsp.2024.101386
L1  - internal-pdf://3251274275/Motivational interviewing for students in scho.pdf
PY  - 2024
SP  - 16
T2  - Journal of School Psychology
TI  - Motivational interviewing for students in school settings: A meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001345418500001
UR  - https://www.sciencedirect.com/science/article/pii/S0022440524001067?via%3Dihub
VL  - 107
ER  -
TY  - JOUR
AB  - OBJECTIVE: The objective of this systematic review was to synthesize evidence from randomized controlled trials on the efficacy of different mind-body therapies (MBTs) in enhancing resilience in adolescents.

METHODS: Randomized controlled trials of different MBTs were identified using electronic databases and manual searches, including PubMed, Embase, Web of Science, Scopus, EBSCOhost, APA PsycINFO, Cochrane Library, and Google database. The Revised Cochrane risk-of-bias tool for randomized trials (RoB 2) was used to assess risk of bias in randomized controlled trials. A narrative synthesis of the included trials was conducted. 

RESULTS: A total of 11 randomized controlled trials involving 3640 adolescents met the inclusion criteria, with 7 trials evaluating the efficacy of Mindfulness, 2 Martial arts, and 2 Yoga. Among the 11 trials, 3 trials reported a significant effect of Mindfulness on resilience in adolescents (Cohen&#039;s d = 0.11 to 0.92), while 2 trials reported a significant effect of Martial arts (Cohen&#039;s d = 0.51 to 0.73). However, 2 trials evaluating Yoga did not find significant improvements in resilience. 

CONCLUSIONS: Due to inconsistencies in the available evidence and heterogeneity across populations, sample sizes, and interventions, it is currently not possible to derive compelling recommendations to guide clinical practice on MBTs for enhancing resilience in adolescents. Whether MBTs can serve as alternative or adjuvant approaches to other established interventions to foster resilience in adolescents and mitigate the physical-health risks caused by stressful environments remains undetermined, necessitating further high-quality randomized controlled trials to evaluate their actual efficacy.
AN  - 39260190
AU  - Mei,
AU  - Z.
AU  - Jiang,
AU  - W.
AU  - Zhang,
AU  - Y.
AU  - Luo,
AU  - S.
AU  - Luo,
AU  - S.
DB  - September 2024.enl
DO  - /10.1016/j.genhosppsych.2024.08.014
L1  - internal-pdf://0361387364/1-s2.0-S016383432400183X-main.cleaned.pdf
PY  - 2024
SP  - 43-51
T2  - General Hospital Psychiatry
TI  - Mind-body therapies for resilience in adolescents: A systematic review of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.genhosppsych.2024.08.014
VL  - 91
ER  -
TY  - JOUR
AB  - Objective: To systematically evaluate and synthesize quantitative evidence regarding the effects of pediatric massage in infants and children under five years. Review methods: We conducted searches in databases including MEDLINE, Embase, Health Technology Assessment Database, the Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects, Allied and Complementary Medicine, Embase, the China National Knowledge Infrastructure, Wanfang Data, SinoMed, and CQVIP up to February 2024. Two reviewers independently screened articles, extracted data, and conducted quality appraisals on the included studies. We focused on systematic reviews with meta-analyses comparing pediatric tuina with a waitlist control, placebo, medication, massage combined with other interventions, and usual care. Outcomes analyzed included physical, psychological, developmental, and safetyrelated measures for children and their caregivers. Methodological quality was assessed using AMSTAR 2, and evidence quality was evaluated using the GRADE approach. Pooled effect estimates and heterogeneity were extracted for each meta-analyzed outcome. Evidence evaluated as &#039;high&#039; and &#039;moderate&#039; quality by GRADEpro with low heterogeneity are presented in the result section. Results: Twenty-two systematic reviews with meta-analysis of 81 outcomes were included. Seven studies (31.8 %) were high quality, and the evidence of 6 (7.4 %) outcomes were evaluated as high quality. The meta-analysis results demonstrate significant benefits of pediatric massage for infants compared to routine care, with increased weight gain (MD 455.07 g; 95 % CI 86.33 to 823.8; I2 = 0 %) based on 2 studies with 157 cases, length growth (MD 1.58 cm; 95 % CI 1.42 to 1.74; I2 = 25 %) from 9 studies with 1294 cases, reduced fussing (MD -0.37 time; 95 % CI -0.53 to -0.21; I2 = 30 %) according to 3 studies with 271 cases, and lower post-intervention bilirubin levels (3 studies/345 cases; MD -31.75 mmol/L; 95 % CI -40.05 to -23.46; I2 = 0 %). Pediatric massage was associated with reduced diarrhea incidence compared to waitlist controls (2 RCTs/ 310 cases; RR 0.39; 95 % CI 0.2 to 0.76; I2 = 0 %) and improved psychomotor development indices (4 RCTs/466 cases; SMD -0.35; 95 % CI -0.54 to -0.15; I2 = 1.06 %). Additionally, pediatric massage significantly enhanced blood oxygen saturation variation post-procedure for pain management (5 RCTs/355 cases; MD 1.05; 95 % CI 0.51 to 1.58; I2 = 0 %). Conclusions: Pediatric massage significantly enhances mother-child attachment, promotes physical growth, reduces fussing, lowers bilirubin levels, improves motor and psychomotor development, as well as manages digestive conditions and pain in children under 5 years. Future research should improve study quality and comprehensively report adverse events.
AN  - WOS:001296093600001
AU  - Chen,
AU  - S.
AU  - C.
AU  - Lin,
AU  - S.
AU  - L.
AU  - Wang,
AU  - M.
AU  - Cheung,
AU  - D.
AU  - S.
AU  - T.
AU  - Liang,
AU  - J.
AU  - G.
AU  - Cheng,
AU  - Z.
AU  - Y.
AU  - Yuen,
AU  - C.
AU  - S.
AU  - Yeung,
AU  - W.
AU  - F.
DB  - September 2024.enl
DO  - 10.1016/j.heliyon.2024.e35993
L1  - internal-pdf://0353718637/1-s2.0-S2405844024120245-main.cleaned.pdf
PY  - 2024
SP  - 16
T2  - Heliyon
TI  - Pediatric massage therapy in infants and children under 5 years: An umbrella review of systematic reviews
UR  - &lt;Go to ISI&gt;://WOS:001296093600001
VL  - 10
ER  -
TY  - JOUR
AB  - **Background**
Rates of asthma are high in children and adolescents, and young people with asthma generally report poorer health outcomes than those without asthma. Young people with asthma experience a range of challenges that may contribute to psychological distress. This is compounded by the social, psychological, and developmental challenges experienced by all people during this life stage. Psychological interventions (such as behavioural therapies or cognitive therapies) have the potential to reduce psychological distress and thus improve behavioural outcomes such as self‐efficacy and medication adherence. In turn, this may reduce medical contacts and asthma attacks.

**Objectives**
To determine the efficacy of psychological interventions for modifying health and behavioural outcomes in children with asthma, compared with usual treatment, treatment with no psychological component, or no treatment.

**Search methods**
We searched the Cochrane Airways Group Specialised Register (including CENTRAL, CRS, MEDLINE, Embase, PsycINFO, CINAHL EBSCO, AMED EBSCO), proceedings of major respiratory conferences, reference lists of included studies, and online clinical databases. The most recent search was conducted on 22 August 2022.

**Selection criteria**
We included randomised controlled trials (RCTs) comparing psychological interventions of any duration with usual care, active controls, or a waiting‐list control in male and female children and adolescents (aged five to 18 years) with asthma.

**Data collection and analysis**
We used standard Cochrane methods. Our primary outcomes were 1. symptoms of anxiety and depression, 2. medical contacts, and 3. asthma attacks. Our secondary outcomes were 1. self‐reported asthma symptoms, 2. medication use, 3. quality of life, and 4. adverse events/side effects.

**Main results**
We included 24 studies (1639 participants) published between 1978 and 2021. Eleven studies were set in the USA, five in China, two in Sweden, three in Iran, and one each in the Netherlands, UK, and Germany. Participants&#039; asthma severity ranged from mild to severe. Three studies included primary school‐aged participants (five to 12 years), two included secondary school‐aged participants (13 to 18 years), and 18 included both age groups, while one study was unclear on the age ranges. Durations of interventions ranged from three days to eight months. One intervention was conducted online and the rest were face‐to‐face.

Meta‐analysis was not possible due to clinical heterogeneity (interventions, populations, outcome tools and definitions, and length of follow‐up). We tabulated and summarised the results narratively with reference to direction, magnitude, and certainty of effects. The certainty of the evidence was very low for all outcomes. A lack of information about scale metrics and minimal clinically important differences for the scales used to measure anxiety, depression, asthma symptoms, medication use, and quality of life made it difficult to judge clinical significance.

Primary outcomes

Four studies (327 participants) reported beneficial or mixed effects of psychological interventions versus controls for symptoms of anxiety, and one found little to no difference between groups (104 participants). Two studies (166 participants) that evaluated symptoms of depression both reported benefits of psychological interventions compared to controls. Three small studies (92 participants) reported a reduction in medical contacts, but two larger studies (544 participants) found little or no difference between groups in this outcome. Two studies (107 participants) found that the intervention had an important beneficial effect on number of asthma attacks, and one small study (22 participants) found little or no effect of the intervention for this outcome.

Secondary outcomes

Eleven studies (720 participants) assessed asthma symptoms; four (322 participants) reported beneficial effects of the intervention compared to control, five (257 participants) reported mixed or unclear findings, and two (131 participants) found little or no difference between groups. Eight studies (822 participants) reported a variety of medication use measures; six of these studies (670 participants) found a positive effect of the intervention versus control, and the other two (152 participants) found little or no difference between the groups. Across six studies (653 participants) reporting measures of quality of life, the largest three (522 participants) found little or no difference between the groups. Where findings were positive or mixed, there was evidence of selective reporting (2 studies, 131 participants). No studies provided data related to adverse effects.

**Authors&#039; conclusions**
Most studies that reported symptoms of anxiety, depression, asthma attacks, asthma symptoms, and medication use found a positive effect of psychological interventions versus control on at least one measure. However, some findings were mixed, it was difficult to judge clinical significance, and the evidence for all outcomes is very uncertain due to clinical heterogeneity, small sample sizes, incomplete reporting, and risk of bias. There is limited evidence to suggest that psychological interventions can reduce the need for medical contact or improve quality of life, and no studies reported adverse events.

It was not possible to identify components of effective interventions and distinguish these from interventions showing no evidence of an effect due to substantial heterogeneity. Future investigations of evidence‐based psychological techniques should consider standardising outcomes to support cross‐comparison and better inform patient and policymaker decision‐making.
AN  - CD013420
AU  - Sharrad,
AU  - K.
AU  - J.
AU  - Sanwo,
AU  - O.
AU  - Cuevas-Asturias,
AU  - S.
AU  - Kew,
AU  - K.
AU  - M.
AU  - Carson-Chahhoud,
AU  - K.
AU  - V.
AU  - Pike,
AU  - K.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/14651858.CD013420.pub2
KW  - *Asthma [therapy]
KW  - *Psychosocial Intervention
KW  - Administrative Personnel
KW  - Adolescent
KW  - Anxiety Disorders
KW  - Anxiety [therapy]
KW  - Child
KW  - Female
KW  - Humans
KW  - Male
L1  - internal-pdf://2607632999/Sharrad_et_al-2024-Cochrane_Database_of_System.pdf
N1  - [Airways]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological interventions for asthma in children and adolescents
UR  - http://dx.doi.org/10.1002/14651858.CD013420.pub2
ER  -
TY  - JOUR
AB  - BACKGROUND: There are over 53million children worldwide under five with developmental disabilities who require effective interventions to support their health and well-being. However, challenges in delivering interventions persist due to various barriers, particularly in low-income and middle-income countries. 

METHODS: We conducted a global systematic umbrella review to assess the evidence on prevention, early detection and rehabilitation interventions for child functioning outcomes related to developmental disabilities in children under 5 years. We focused on prevalent disabilities worldwide and identified evidence-based interventions. We searched Medline, Embase, PsychINFO, and Cochrane Library for relevant literature from 1st January 2013 to 14th April 2023. A narrative synthesis approach was used to summarise the findings of the included meta-analyses. The results were presented descriptively, including study characteristics, interventions assessed, and outcomes reported. Further, as part of a secondary analysis, we presented the global prevalence of each disability in 2019 from the Global Burden of Disease study, identified the regions with the highest burden and the top ten affected countries. This study is registered with PROSPERO, number CRD42023420099. 

RESULTS: We included 18 reviews from 883 citations, which included 1,273,444 children under five with or at risk of developmental disabilities from 251 studies across 30 countries. The conditions with adequate data were cerebral palsy, hearing loss, cognitive impairment, autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder. ASD was the most prevalent target disability (n = 8 reviews, 44%). Most reviews (n = 12, 67%) evaluated early interventions to support behavioural functioning and motor impairment. Only 33% (n = 10/30) of studies in the reviews were from middle-income countries, with no studies from low-income countries. Regarding quality, half of reviews were scored as high confidence (n = 9/18, 50%), seven as moderate (39%) and two (11%) as low. 

CONCLUSIONS: We identified geographical and disability-related inequities. There is a lack of evidence from outside high-income settings. The study underscores gaps in evidence concerning prevention, identification and intervention, revealing a stark mismatch between the available evidence base and the regions experiencing the highest prevalence rates of developmental disabilities.
AN  - 38302917
AU  - Smythe,
AU  - T.
AU  - Scherer,
AU  - N.
AU  - Nanyunja,
AU  - C.
AU  - Tann,
AU  - C.
AU  - J.
AU  - Olusanya,
AU  - B.
AU  - O.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1186/s12916-024-03265-7
L1  - internal-pdf://3677968889/Smythe-2024-Strategies for addressing the need.pdf
PY  - 2024
SP  - 51
T2  - BMC Medicine
TI  - Strategies for addressing the needs of children with or at risk of developmental disabilities in early childhood by 2030: a systematic umbrella review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38302917
UR  - https://bmcmedicine.biomedcentral.com/counter/pdf/10.1186/s12916-024-03265-7.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - PROPOSE: To review published Physical Activity (PA) on the Mental Health of Children and Adolescents aged 5 to 18 years during COVID-19 pandemic-induced school closures. 

METHODS: From the database creation to April 2022, 10 databases are retrieved, with 4427 records filtered, 14 included in this research. The research takes Agency for Healthcare Research and Quality (AHRQ) evaluation standards. 

RESULTS: The thesis selects 14 studies from 6 countries, involving 400009 children and adolescents. These studies happened during the lockdown of COVID-19 (from December 2019 to April 2021). During the lockdown of COVID-19, schools were closed, which was considered part of a more extensive lockdown. Schools were closed for 1 to 4 weeks. There were 10 high quality studies (71.4%) and 4 medium quality studies (28.6%). 4 studies report that the pandemic reduces the time of PA but increases the time of watching screen and sitting. 10 studies (71.4%) identify that PA is positive for the mental health, because it helps reduce mental symptoms to a certain extent, especially anxiety, depression, and emotional disorders. 5 studies show that PA may not improve the mental health of children and adolescents under 12 during the pandemic. 4 studies indicate that the influence of PA on mental health of children and adolescents is determined by the amount of activity, including the extent, intensity, frequency, and duration, etc. 

CONCLUSIONS: In this narrative synthesis of reports from the class suspension period, reports that PA has a improve on the mental health of children and adolescents to a certain extent. it is found that PA may be helpful in reducing mental health symptoms of children and adolescents who are influenced by class suspension because of the COVID-19 pandemic. Therefore, stakeholders of the mental health of children and adolescents around the world should recommend PA because it is a practicable and beneficial way for long-term mental support.
AN  - 38917211
AU  - Zhong,
AU  - B.
AU  - Sun,
AU  - H.
AU  - Wang,
AU  - G.
AU  - Junwen,
AU  - S.
AU  - Tang,
AU  - S.
AU  - Gao,
AU  - Y.
AU  - Chen,
AU  - H.
AU  - Lu,
AU  - T.
AU  - Yan,
AU  - J.
DB  - Juni 24.enl
DO  - /10.1371/journal.pone.0299158
L1  - internal-pdf://3973869435/Zhong-2024-Physical activity on the mental hea.pdf
PY  - 2024
SP  - e0299158
T2  - PLoS ONE [Electronic Resource]
TI  - Physical activity on the mental health of children and adolescents during COVID-19 pandemic-induced school closures-A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.1371%2fjournal.pone.0299158
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0299158&amp;type=printable
VL  - 19
ER  -
TY  - JOUR
AB  - The most frequently performed invasive procedures in hospitals and healthcare centers are needle-related procedures, such as intravenous cannulation and phlebotomy, and they are identified as the major sources of pain, fear, and anxiety in children and adolescents. The objective of this systematic review was to evaluate the effectiveness of VR as a distraction measure to reduce pain, fear, and anxiety in children and adolescents undergoing needle-related invasive procedures. For this purpose, the CINAHL, Scopus, WOS, and Cochrane Library scientific databases were used. The protocol review was registered in PROSPERO (ID:42024563245), and inclusion and exclusion criteria were applied. Twenty-one studies were included in the systematic review, involving a total of 2663 participants. Significant differences favored the use of virtual reality for the control of pain intensity (WBFSpatients p = 0.001; MD = -1.83; 95% CI -2.93 to -0.72; WBFSparents p = 0.0002; MD = -2.61; 95% CI -4.00 to -1.23; WBFSnurses p = 0.0001; MD = -2.71; 95% CI -2.82 to -2.60; VAS/NRS p = 0.001, MD = -0.71; 95% CI -1.13 to -0.28), anxiety (CAMpatient p = 0.02, MD = -2.92; 95% CI -5.45 to -0.38; CAMparents p = 0.01, MD = -3.87; 95% CI -6.99 to -0.75) and fear (CFSpatients p = 0.0005, MD = -1.27; 95% CI -1.99 to -0.56; CFSparents p = 0.0005, MD = -1.33; 95% CI -2.08 to -0.58; and CFSnurses p = 0.04, MD = -1.13; 95% CI -2.24 to -0.03). However, high heterogeneity was noted. The use of virtual reality as a distraction appears to be a valuable strategy for reducing pain, fear, and anxiety during needle-related procedures, although further studies with higher methodological rigor, based on a standardized protocol, are needed.
AN  - 39311190
AU  - Caceres-Matos,
AU  - R.
AU  - Castillo-Garcia,
AU  - M.
AU  - Magni,
AU  - E.
AU  - Pabon-Carrasco,
AU  - M.
DB  - September 2024.enl
DO  - /10.3390/nursrep14030182
L1  - internal-pdf://0577720841/Caceres-Matos-2024-Effectiveness of Virtual Re.pdf
PY  - 2024
SP  - 2456-2484
T2  - Nursing Reports
TI  - Effectiveness of Virtual Reality for Managing Pain, Fear, and Anxiety in Children and Adolescents Undergoing Needle-Related Procedures: Systematic Review with Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3390%2fnursrep14030182
UR  - https://mdpi-res.com/d_attachment/nursrep/nursrep-14-00182/article_deploy/nursrep-14-00182-v3.pdf?version=1727243131
VL  - 14
ER  -
TY  - JOUR
AB  - Background and aims: Internet addiction (IA) has been identified as a major public health problem that is more prominent in adolescents and young adults. Some researchers have indicated certain advantages of family-based therapy over other treatments in participants with IA, but no conclusive evaluation has been reported. The present meta-analysis aims to review the efficacy of family-based therapy on Internet addiction in adolescents and young adults. 

Methods: Relevant articles published from 1996 to February 15th, 2024, were searched from 14 databases, including three Chinese databases. A total of 19,590 articles were identified using a combination of three sets of search terms (Internet addiction, family therapy, and adolescents). Only RCTs and nonrandomized controlled trials were included. 

Results: 18 studies, most of which were conducted in Asian countries, were included in the final data analysis. The overall severity of Internet addiction in the family-based therapy group was significantly lower than that in the control group. However, significant heterogeneity was detected. Subgroup analysis showed a beneficial effect of family-based therapy when compared with non-intervention and when added to another psychological or behavioural therapy in psychiatric patients with co-medication. Few studies have examined secondary outcomes or follow-up effects.

Discussion and Conclusions: Family-based therapy is most effective in reducing the severity of Internet addiction when combined with other therapies, especially medication treatments in psychiatric patients. It might also be helpful to relieve depression and enhance family functions, which needs further evidence. More studies following up on the post-intervention effects are recommended in the future.
AN  - 38635339
AU  - Wang,
AU  - H.
AU  - Li,
AU  - X.
AU  - Lok,
AU  - G.
AU  - K.
AU  - I.
AU  - Meng,
AU  - C.
AU  - Tan,
AU  - Y.
AU  - Lee,
AU  - U.
AU  - M.
AU  - Lei,
AU  - L.
AU  - S.
AU  - M.
AU  - Chan,
AU  - N.
DB  - April 24.enl
DO  - /10.1556/2006.2024.00015
L1  - internal-pdf://2781234095/Wang-2024-Family-based therapy for internet ad.pdf
PY  - 2024
SP  - 17
T2  - Journal of Behavioral Addictions
TI  - Family-based therapy for internet addiction among adolescents and young adults: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1556%2f2006.2024.00015
UR  - https://akjournals.com/downloadpdf/view/journals/2006/aop/article-10.1556-2006.2024.00015/article-10.1556-2006.2024.00015.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - Background
Postpartum depression (PPD) is a condition that can affect any woman regardless of ethnicity, age, party, marital status, income, and type of delivery. This condition is highly prevalent worldwide. PPD, if not treated timely, can affect the maternal-child bond and can have a detrimental impact on the future cognitive, emotional, and behavioral development of the child. Interpersonal psychotherapy (IPT) has been reported as an effective treatment of PPD in previous studies as this focuses on relationship and social support issues. Previous reviews conducted in developed nations have reported the superior efficacy of IPT in comparison to other treatment options. There is no systematic review conducted in low to middle-income countries on the efficacy of IPT on PPD. Therefore it was necessary to undertake a systematic review to assess the effectiveness of IPT in reducing the depression among postpartum women in low and middle-income countries (LMICs).

Objectives
The main aim of this systematic review was to assess the effectiveness of IPT alone or in conjunction with pharmacological therapy and/or other psychological and psychosocial interventions, in reducing depressive symptoms among women diagnosed with PPD residing in LMICs.

Search Methods
The systematic search encompassed several prominent databases and grey literature. Furthermore, experts specializing in the field of IPT were consulted to identify any relevant studies conducted in LMICs that fulfilled the predetermined eligibility criteria. The most recent search update was performed in July 2022.

Selection Criteria
The PICOS criteria were meticulously defined for this review as described. Participants: Postpartum women diagnosed with PPD in LMICs were included. Intervention: IPT either as a standalone treatment or in conjunction with pharmacological therapy was included. Comparison: any form of psychological therapy or pharmacological therapy, whether administered individually or in combination, was considered for comparison. Study designs: experimental and quasi-experimental, factorial designs, and quantitative components (experimental, quasi-experimental, factorial designs) of mixed methods designs were eligible to be included. Studies with single-group study designs and qualitative studies were excluded from the review.

Data Collection and Analysis
Two reviewers from our team conducted a rigorous screening process to determine the eligibility of articles for inclusion. This involved an initial evaluation of titles and abstracts, followed by a comprehensive assessment of the full text of selected articles. In instances where discrepancies arose between the two reviewers, resolution was achieved through discussion or consultation with a third author to establish a consensus. Following the screening process, two team members independently extracted pertinent information and data from the studies that met the inclusion criteria. The treatment effect of the intervention, in comparison to the control group, was subsequently analyzed utilizing the fixed effects model taking into account the small number of studies.

Main Results
A total of 17,588 studies were identified from various databases, and 6493 duplicate studies were removed. Subsequently, 9380 studies underwent independent title and abstract screening resulting in the exclusion of 9040 studies. 345 full texts were thoroughly assessed leading to the exclusion of 341 studies, finally including 4 studies for review. The four included trials were randomized trials and comprised a total sample size of 188 women diagnosed with PPD residing in LMICs. Among these studies, three compared IPT with usual treatment, while one study compared IPT with antidepressant medications (ADMs). In terms of the providers of IPT, in one study, IPT was administered by nurses, while psychologists delivered IPT in another study. In one study, community health workers were responsible for providing IPT. However, in one study, information regarding the specific providers of IPT was not available or reported. The primary outcome measure reported in all four studies was depression, assessed using the Edinburgh Postnatal Depression Scale (EPDS). The geographical distribution of the studies included; one conducted in Zambia, one in Kenya, one in Pakistan, and one in Iran. Out of the four studies, three were included in the meta-analysis, as missing data from one study could not be obtained. Based on the overall treatment effect, it was found that depression scores decreased significantly more in the IPT group compared to other interventions (usual treatment or ADMs) (standardized mean difference [SMD] &minus;0.62, 95% confidence interval [CI] (&minus;1.01, &minus;0.23), Z&thinsp;=&thinsp;3.13 (p&thinsp;=&thinsp;0.002), &chi;2&thinsp;=&thinsp;49.49; df&thinsp;=&thinsp;2; p&thinsp;&lt;&thinsp;0.00001; I2&thinsp;=&thinsp;96%; 3 studies, n&thinsp;=&thinsp;136). Out of the three studies, two studies compared the effectiveness of IPT in reducing depression scores specifically when compared to the usual treatment, and in both studies, depression scores were reduced significantly in the IPT group as compared to the usual treatment group. Only one study directly compared the effectiveness of IPT with ADM, reporting that IPT was more effective than ADM in reducing depression scores among postpartum women. Regarding adverse outcomes, only one study reported suicidal ideation with one participant in the IPT group and two in the ADM group (RR 0.50, 95% CI (0.05, 5.30), p&thinsp;=&thinsp;0.56, n&thinsp;=&thinsp;78). The same study reported seven participants in the ADM group had adverse drug reactions as compared to none in the IPT group (RR 15.0, 95% CI (0.89, 254), p&thinsp;=&thinsp;0.06, n&thinsp;=&thinsp;78).

Authors&#039; Conclusions
Our comprehensive search yielded a limited number of four studies conducted in such settings. Despite the scarcity of available evidence, the findings collectively suggest that IPT is indeed an effective treatment for reducing PPD when compared to usual treatment and pharmacological therapy. However given the low certainty of evidence, there is a need for further research in the form of well-designed randomized controlled trials with larger sample sizes and a reduced risk of bias. Such studies would greatly contribute to enhancing the strength and reliability of the evidence base regarding the effectiveness of IPT in the context of PPD in LMICs. The knowledge generated from future research endeavors would be highly valuable in guiding the development of more affordable and cost-effective treatment approaches for PPD in resource-limited settings.
AU  - Kang,
AU  - H.
AU  - K.
AU  - Bisht,
AU  - B.
AU  - Kaur,
AU  - M.
AU  - Alexis,
AU  - O.
AU  - Worsley,
AU  - A.
AU  - John,
AU  - D.
DB  - April 24.enl
DO  - /10.1002/cl2.1399
L1  - internal-pdf://3447832218/Campbell Systematic Reviews - 2024 - Kang - Ef.pdf
PY  - 2024
T2  - Campbell Systematic Reviews
TI  - Effectiveness of interpersonal psychotherapy in comparison to other psychological and pharmacological interventions for reducing depressive symptoms in women diagnosed with postpartum depression in low- and middle-income countries: A systematic review
ER  -
TY  - JOUR
AB  - The association of enteral micronutrient supplementation and the neurodevelopmental outcomes of preterm or low birth weight (LBW) infants is controversial. This research was prospectively registered (CRD42023454034). We searched MEDLINE, Embase, PsycInfo, ClinicalTrials. gov, and the Cochrane Library for randomised clinical trials (RCTs) or quasi-RCTs comparing any enteral micronutrients supplementation with placebo or no supplementation in preterm or LBW infants. The primary outcome was neurodevelopmental impairment (NDI), with secondary outcomes involving various neurodevelopmental tests and disabilities. There was no evidence of an association between enteral micronutrients supplementation and the risk of NDI (RR, 1.03; 95% CI, 0.93-1.14; moderate certainty evidence). There was no evidence that the supplemented groups enhanced cognitive (MD, 0.65; 95% CI, -0.37 to 1.67; low certainty evidence), language (SMD, -0.01; 95% CI, -0.11 to 0.09; moderate certainty evidence), or motor scores (SMD, 0.04; 95% CI, -0.06 to 0.15; very low certainty evidence) or IQ (SMD, -0.20; 95% CI, -0.53 to 0.13; very low certainty evidence). Subgroup analysis showed that multiple micronutrients supplementation improved expressive language score (MD, 1.42; 95% CI, 0.39-2.45), and zinc supplementation enhanced fine motor score (SMD, 1.70; 95% CI, 0.98-2.43). The overall heterogeneity was low. This study demonstrates that enteral micronutrient supplementation is associated with little or no benefits in neurodevelopmental outcomes for preterm or LBW infants. Well-designed RCTs are needed to further ascertain these associations.
AN  - 39449037
AU  - Liu,
AU  - Y.
AU  - Jin,
AU  - S.
AU  - Zhang,
AU  - G.
AU  - Chen,
AU  - T.
AU  - Huang,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1111/mcn.13756
L1  - internal-pdf://1411644576/Maternal Child Nutrition - 2024 - Liu - Ente.pdf
PY  - 2024
SP  - e13756
T2  - Maternal &amp; Child Nutrition
TI  - Enteral micronutrient supplementation and neurodevelopmental outcomes in preterm or low birth weight infants: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1111%2fmcn.13756
ER  -
TY  - JOUR
AB  - Mental disorders, most commonly anxiety disorders and fourth most common depression, are prevalent in children and adolescents. Internet- and mobile-based interventions might represent a scalable approach to improve mental health care, however, evidence so far is inconclusive and systematic reports on negative effects are missing. Four data-bases were searched for randomized controlled trials evaluating internet- and mobile-based interventions (IMIs) targeting anxiety disorders or depression in children and adolescents up to 18 years exhibiting clinically relevant symptoms. Meta-analytic evaluations were conducted in comparison to active and passive control groups, furthermore, pre-defined sub-groups were explored and reported negative effects examined. Pooled estimates showed a moderate positive effect for IMIs targeting anxiety disorders compared to passive control groups (g = -0.69; CI -0.94 to -0.45; k = 8; n = 559; p &lt;= 0,001), but not for depression. Pooled estimates compared to active control groups remained non-significant. Subgroup analyses were largely omitted due to an insufficient number of trials or were non-significant. Negative effects were mainly reported as drop-out rates and (non)-response rates, while additional negative effects, such as deterioration rates or the development of additional symptoms, were reported by only one third of included studies. The focus on children and adolescents with clinically relevant symptoms allowed the present findings to complement previous work, however, the limited amount of trials hindered many planned comparisons. The overview of reported negative effects highlighted that negative effects are being neglected in the majority of RCTs. Hence, in the future RCTs should include more information about potential negative effects, at best a combination of quantitative and qualitative information. Open Science Framework (osf.io/ch5nj).
AN  - 38430237
AU  - Dulsen,
AU  - P.
AU  - Baumeister,
AU  - H.
DB  - Mars 24.enl
DO  - /10.1007/s00787-024-02404-y
L1  - internal-pdf://1593427126/Dulsen-2024-Internet- and mobile-based anxiety.pdf
PY  - 2024
SP  - 02
T2  - European Child &amp; Adolescent Psychiatry
TI  - Internet- and mobile-based anxiety and depression interventions for children and adolescents: efficacy and negative effects - a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs00787-024-02404-y
UR  - https://link.springer.com/content/pdf/10.1007/s00787-024-02404-y.pdf
VL  - 02
ER  -
TY  - JOUR
AB  - This meta -analysis examines the efficacy of the cognitive behavioral approach to interventions toward the improvement of executive function for children/ adolescents with high -functioning autism spectrum disorder (HF-ASD). This meta -analysis paper has identified ten studies involving 437 participants with high -functioning autism spectrum disorder aged between 5 and 18. All the participants reported IQs were at or above 70. A random effect meta -analysis yielded a moderately significant effect (Hedge g = 0.72) with significant heterogeneity [Q(10) = 228.36, p &lt; .001]. There were considerable variations in the executive function domain, i.e., working memory (hedge g = 1.23) and inhibition (g = 0.47), showing significant treatment effects. On the other hand, cognitive flexibility (g = -0.51) and planning (g = -0.07) show non -significant effects toward cognitive behavioral interventions. The finding suggests that the cognitive behavioral approach to intervention demonstrates efficacy in improving executive function in children or adolescents with high -functioning autism spectrum disorder. All the cognitive behavioral intervention studies were conducted in developed countries, so differences between the approaches between developed and developing countries were inconclusive. Future studies are needed to investigate the effectiveness of cognitive behavioral techniques in intervention for low -functioning autism spectrum disorder children.
AN  - WOS:001233711800001
AU  - Kaur,
AU  - K.
AU  - Pany,
AU  - S.
AU  - Mohanty,
AU  - S.
AU  - P.
AU  - Sahoo,
AU  - P.
AU  - K.
AU  - Rana,
AU  - S.
DB  - Juni 24.enl
DO  - 10.52291/ijse.2024.39.2
L1  - internal-pdf://2724162388/Kaur-2024-Efficacy of Cognitive Behavioral Int.pdf
PY  - 2024
SP  - 11-20
T2  - International Journal of Special Education
TI  - Efficacy of Cognitive Behavioral Intervention in Improving Executive Function of Children with High Functioning Autism Spectrum Disorder: A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001233711800001
UR  - https://internationalsped.com/ijse/article/download/1257/140
VL  - 39
ER  -
TY  - JOUR
AB  - **Background**: Executive functions is a crucial ability in the early development of preschool children. While numerous studies have found that music training has a favourable effect on children&#039;s executive functions, there is a lack of a consistent perspective on this topic, particularly with regard to the dose-response relationship. **Methods**: Systematic searches were conducted of Web of Science, PubMed, Scopus, and China National Knowledge Infrastructure. A random-effects meta-analysis was used to compute standardized mean differences (SMD) and 95% confidence intervals (CI). **Results**: In all, 10 studies were included in the meta-analysis, in which children&#039;s music training groups showed significantly improved inhibitory control (SMD=0.38, 95% CI: 0.16-0.6), working memory (SMD=0.35, 95% CI: 0.16-0.54), and cognitive flexibility (SMD=0.23, 95% CI: 0.04-0.42) in comparison with control groups. Subgroup analyses indicated significant improvements relative to the control groups for inhibitory control following music training having a duration of &gt;=12weeks (SMD=0.51, 95% CI: 0.22-0.8), occurring &gt;=3 times per week (SMD=0.48, 95% CI: 0.2-0.75), and lasting 20-30min per session (SMD=0.42, 95% CI: 0.2-0.63). Significant improvements were seen for working memory following music training having a duration of &gt;=12weeks (SMD=0.42, 95% CI: 0.18-0.65), occurring &lt;3 times per week (SMD=0.49, 95% CI: 0.06-0.93), occurring &gt;=3 times per week (SMD=0.28, 95% CI:0.1-0.47), and lasting 20-30min per session (SMD=0.39, 95% CI: 0.16-0.54). Music training significantly improved cognitive flexibility following training having a duration of &gt;=12weeks (SMD=0.22, 95% CI: 0.04-0.41), occurring &gt;=3 times per week (SMD=0.19, 95% CI: 0.0-0.39), and lasting &gt;40min per session (SMD=0.74, 95% CI: 0.22-1.26). **Conclusion**: Music training has a positive effect on inhibitory control, working memory, and cognitive flexibility in preschool children aged 3-6years. This effect is influenced by certain training factors, including the duration of the intervention period, frequency per week, and length of each session. **Systematic review registration**: https://www.crd.york.ac.uk/prospero/#aboutregpage, CRD42024513482.
AN  - 39881691
AU  - Lu,
AU  - Y.
AU  - Shi,
AU  - L.
AU  - Musib,
AU  - A.
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fpsyg.2024.1522962
L1  - internal-pdf://0617813721/Lu-2024-Effects of music training on executive.pdf
PY  - 2024
SP  - 1522962
T2  - Frontiers in Psychology
TI  - Effects of music training on executive functions in preschool children aged 3-6years: systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffpsyg.2024.1522962
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11775157/pdf/fpsyg-15-1522962.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Third wave interventions have demonstrated efficacy as a treatment option to promote wellbeing in adolescents. Evidence of their effectiveness for chronic mental health disorders remains unclear. The PubMed, PsycINFO, ProQuest, Embase, and CINAHL databases were searched from inception until March 2024 for five established interventions: acceptance and commitment therapy (ACT), compassion focused therapy, dialectical behaviour therapy (DBT), mindfulness-based cognitive therapy, and mindfulness-based stress reduction (MBSR). Risk of bias was assessed (QualSyst tool), and standardized mean group differences (Hedges&#039; g) with associated p-values, 95% confidence intervals, and prediction intervals calculated. Three randomized controlled trials and 10 singlegroup designs, all assessing DBT and representing 700 adolescents (most with subthreshold or full syndrome borderline personality disorder), were included. All studies were of sound methodological quality. DBT was associated with large and significant reductions in mental health symptoms (depression, anxiety, emotional regulation, suicidal ideation, self-harm, and BPD symptoms; g range = 0.69 to 1.05) - although individual variability in treatment response was noted. Symptom improvements were maintained at follow-up (g range = 0.70 to 1.71), although based on limited data. Neither DBT intensity nor duration significantly moderated treatment effects. DBT is the most assessed intervention for adolescents with severe emotional or behavioral problems. Additional controlled studies with diverse samples are needed to confirm the unique effects of DBT relative to other promising third wave interventions. Protocol registration: Open Science Framework [htt ps://osf.io/fgd2j/].
AN  - WOS:001346823200001
AU  - Sandery,
AU  - P.
AU  - Baranoff,
AU  - J.
AU  - Dorstyn,
AU  - D.
DB  - November 2024.enl
DO  - 10.1016/j.jcbs.2024.100841
L1  - internal-pdf://3943792327/1-s2.0-S2212144724001212-main.cleaned.pdf
PY  - 2024
SP  - 13
T2  - Journal of Contextual Behavioral Science
TI  - Third wave interventions for adolescents with mental health disorders: A systematic review with meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001346823200001
UR  - https://www.sciencedirect.com/science/article/pii/S2212144724001212?pes=vor&amp;utm_source=clarivate&amp;getft_integrator=clarivate
VL  - 34
ER  -
TY  - JOUR
AB  - Objective: Non-invasive brain stimulation (NIBS) is beneficial to adult patients with depression, but its safety and efficacy in combination with antidepressants in children and adolescents with depression are not clear. We conducted a preliminary meta-analysis to objectively evaluate its clinical effect and provide information for future research and clinical practice. 

Methods: PubMed, Cochrane Library, Embase, and Web of Science were searched systematically to find clinical trials published in English before April 11, 2023. Stata software was used for meta-analysis, and random or fixed effect models were used to combine effect sizes. 

Results: Nine studies were eligible and included (n = 393). No articles about children were included in the analysis. The results showed that the remission rate was 40% (95% confidence interval [CI]: 13% to 71%). The scores of Children&#039;s Depression Rating Scale (CRDS) and Hamilton&#039;s depression scale (HAMD) significantly decreased compared to baseline value (MD = -27.04, 95% CI: -30.95, -23.12 and MD = -12.78, 95% CI: -19.55 to -6.01). In addition, the incidence of all adverse events was 13% (95% CI: 5%, 23%), and all were minor pain-related events. 

Conclusion: The combination of NIBS and antidepressants has been shown to notably alleviate depressive symptoms in adolescents, offering a considerable level of safety. This therapeutic synergy is particularly effective in patients with major depressive disorder, where repetitive transcranial magnetic stimulation augmented with antidepressants can enhance the amelioration of depressive symptoms. 

Systematic review registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023442215, PROSPERO CRD42023442215.
AN  - 38426000
AU  - Li,
AU  - Y.
AU  - Liu,
AU  - X.
DB  - Mars 24.enl
DO  - /10.3389/fpsyt.2024.1288338
L1  - internal-pdf://4084581667/Li-2024-Efficacy and safety of non-invasive br.pdf
PY  - 2024
SP  - 1288338
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Efficacy and safety of non-invasive brain stimulation in combination with antidepressants in adolescents with depression: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3389%2ffpsyt.2024.1288338
UR  - https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2024.1288338/pdf
VL  - 15
ER  -
TY  - JOUR
AB  - This review assessed the effectiveness of ECEC-based interventions to improve child physical activity, and intervention impact on child weight-based anthropometrics, fundamental movement skills (FMS), cognitive functioning, and social-emotional wellbeing. Adverse effects and costs were assessed. Finch et al&#039;s 2014 systematic review was updated. Electronic databases were searched 10 September 2014 to 27 October 2022. Included studies were randomized controlled trials of ECEC interventions targeting physical activity among children aged 0-6 years. The methodological quality of studies was assessed using Cochrane&#039;s Risk of Bias tool v2. Standardized mean differences (SMD) were calculated for each outcome with meta-analysis undertaken; otherwise, findings were described narratively. Fifty-three studies were included. ECEC-based interventions were found to significantly improve child physical activity (SMD 0.193, 95% confidence interval [CI] 0.09 to 0.3; p &lt; 0.001) and FMS (SMD 0.544, 95% CI 0.1 to 0.98; p = 0.015), compared to control. Small positive, but non-significant, effects were found for weight-based anthropometrics, cognitive functioning, and social-emotional wellbeing. Few studies reported adverse effects (n = 10), and no studies reported formal economic analyses. While ECEC-based interventions can significantly improve child physical activity and FMS, further evidence of their impact on cognitive functioning, social-emotional wellbeing, and the cost-effectiveness of such interventions is required to inform policy and practice.
AN  - WOS:001358520500001
AU  - Grady,
AU  - A.
AU  - Lorch,
AU  - R.
AU  - Giles,
AU  - L.
AU  - Lamont,
AU  - H.
AU  - Anderson,
AU  - A.
AU  - Pearson,
AU  - N.
AU  - Romiti,
AU  - M.
AU  - Lum,
AU  - M.
AU  - Stuart,
AU  - A.
AU  - Leigh,
AU  - L.
AU  - Yoong,
AU  - S.
AU  - L.
DB  - November 2024.enl
DO  - 10.1111/obr.13852
L1  - internal-pdf://1328119917/Grady-2024-The impact of early childhood educa.pdf
PY  - 2024
SP  - 20
T2  - Obesity Reviews
TI  - The impact of early childhood education and care-based interventions on child physical activity, anthropometrics, fundamental movement skills, cognitive functioning, and social-emotional wellbeing: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001358520500001
ER  -
TY  - JOUR
AB  - BACKGROUND: Cognitive Behavioural Therapy (CBT) has been proven to be effective for anxiety and depression in children and young people (CYP). Over the past 20 years there have been several attempts at delivering CBT through apps, online software, videogames, but also with a therapist via phone or videoconferencing platforms, with promising results for the &quot;technology-assisted&quot; versions. However, most research, have compared online CBT to waiting lists, and not many studies looked at the effectiveness of face-to-face (f2f) CBT versus technology-assisted CBT. 

METHODS: Adopting the PRISMA guidelines, we evaluated 1849 citations and identified 10 eligible studies. Studies were identified through the Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, PubMed/MEDLINE, Web of Science, and Scopus. 

RESULTS: Ten studies met our inclusion criteria. The studies included a variety of technology-assisted forms of CBT, including videoconferencing and online CBT. Of these, seven looked at the effectiveness of technology-assisted CBT for anxiety in CYP, and seven looked at depression. The meta-analyses had low heterogeneity and showed that technology-assisted CBT was non-inferior to f2f CBT for anxiety and depression in CYP (d = 0.06 and 0.12 respectively). 

CONCLUSIONS: Technology-assisted CBT may be a valid alternative for the treatment of anxiety and depression in CYP. Future studies should consider what specific delivery modalities are most cost-effective.
AN  - 38870346
AU  - Bevilacqua,
AU  - L.
AU  - Fox-Smith,
AU  - L.
AU  - Lampard,
AU  - O.
AU  - Rojas,
AU  - N.
AU  - Zavitsanou,
AU  - G.
AU  - Meiser-Stedman,
AU  - R.
AU  - Beazley,
AU  - P.
DB  - Juni 24.enl
DO  - /10.1177/13591045241259070
L1  - internal-pdf://0843279126/bevilacqua-et-al-2024-effectiveness-of-technol.pdf
PY  - 2024
SP  - 13591045241259070
T2  - Clinical Child Psychology &amp; Psychiatry
TI  - Effectiveness of technology-assisted vs face-to-face cognitive behavioural therapy for anxiety and depression in children and young people: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1177%2f13591045241259070
UR  - https://journals.sagepub.com/doi/10.1177/13591045241259070
ER  -
TY  - JOUR
AB  - Many students who experience behavioral difficulties (BD) also experience learning difficulties (LD) in school; however, little research exists on how to support the academic achievement of students with co-occurring BD/LD. Even less research exists for students who experience these co-occurring difficulties at the high school or secondary level. The goal of this synthesis was to explore the effects of academic interventions on the academic outcomes (i.e., reading, mathematics, and writing) of high school students with co-occurring BD/LD. A total of nine, single-case design studies met criteria for this synthesis, including two dissertations. Four studies examined mathematics outcomes, four studies assessed reading outcomes, and two studies targeted spelling outcomes, with one study examining both mathematics and spelling. The calculated Tau-U effect sizes ranged from 0.54 to 1.0 across studies. Implications for research and practice are discussed with the goal of contributing to the small body of research on secondary-aged students with co-occurring BD/LD.
AN  - WOS:001275136300001
AU  - Payne,
AU  - S.
AU  - B.
AU  - Yoon,
AU  - N.
AU  - Y.
DB  - August 2024.enl
DO  - 10.1177/01987429241261969
L1  - internal-pdf://1567513595/Payne-2024-A Synthesis of Academic Interventio.pdf
PY  - 2024
SP  - 11
T2  - Behavioral Disorders
TI  - A Synthesis of Academic Interventions for High School Students With Behavioral and Learning Difficulties
UR  - &lt;Go to ISI&gt;://WOS:001275136300001
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** This study aimed to assess the effects of art therapy on anxiety among children and adolescents. 

**METHODS:** We searched several databases, including PubMed, Web of Science, Embase (via Ovid), PsychINFO (through EBSCO), and The Cochrane Library, comprising the Cochrane Database of Systematic Reviews and the Cochrane Central Register of Controlled Trials. Additionally, Chinese databases such as CNKI (China National Knowledge Infrastructure) and Wan Fang Data were explored from their beginnings until October 22, 2023. Studies that investigated the impact of art therapy on anxiety compared to a control group were included. The methodological quality of these randomized controlled trials was evaluated using the Cochrane Handbook&#039;s risk of bias instrument. 

**RESULTS:** Six studies involving 422 participants were included. The findings indicated a notable decrease in anxiety symptoms due to art therapy, with a Standardized Mean Difference (SMD) of -1.42, 95% Confidence Interval (95%CI -2.33, -0.51), p &lt; 0.002. Notably, there was pronounced heterogeneity, as evidenced by Tau&lt;sup&gt;2&lt;/sup&gt; = 1.41, Chi&lt;sup&gt;2&lt;/sup&gt; = 101.19, df = 6, and I2 = 94%, with Z = 3.06. 

**CONCLUSION:** Art therapy significantly improved the anxiety symptoms of children and adolescents, positioning it as an effective means of treating anxiety.
AN  - 38936289
AU  - Zhang,
AU  - B.
AU  - Wang,
AU  - J.
AU  - Abdullah,
AU  - A.
AU  - B.
DB  - Juni 24.enl
DO  - /10.1016/j.clinsp.2024.100404
L1  - internal-pdf://0065170776/1-s2.0-S1807593224000814-main.cleaned.pdf
PY  - 2024
SP  - 100404
T2  - Clinics (Sao Paulo, Brazil)
TI  - The effects of art therapy interventions on anxiety in children and adolescents: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.clinsp.2024.100404
VL  - 79
ER  -
TY  - JOUR
AB  - Background
Among youth, symptoms of depression, anxiety, and alcohol use are associated with considerable illness and disability. Youth face many personal and health system barriers in accessing mental health care. Mobile applications (apps) offer youth potentially accessible, scalable, and anonymous therapy and other support. Recent systematic reviews on apps to reduce mental health symptoms among youth have reported uncertain effectiveness, but analyses based on the type of app-delivered therapy are limited.

Objectives
We conducted this systematic review with youth co-researchers to ensure that this review addressed the questions that were most important to them. The objective of this review is to synthesize the best available evidence on the effectiveness of mobile apps for the reduction of depressive symptoms (depression, generalized anxiety, psychological distress) and alcohol use among youth.

Search Methods
We conducted electronic searches of the following bibliographic databases for studies published between January 1, 2008, and July 1, 2022: MEDLINE (via Ovid), Embase (via Ovid), PsycINFO (via Ovid), CINAHL (via EBSCOHost), and CENTRAL (via the Cochrane Library). The search used a combination of indexed terms, free text words, and MeSH headings. We manually screened the references of relevant systematic reviews and included randomized controlled trials (RCTs) for additional eligible studies, and contacted authors for full reports of identified trial registries or protocols.

Selection Criteria
We included RCTs conducted among youth aged 15&ndash;24 years from any setting. We did not exclude populations on the basis of gender, socioeconomic status, geographic location or other personal characteristics. We included studies which assessed the effectiveness of app-delivered mental health support or therapy interventions that targeted the management of depressive disorders and/or alcohol use disorders. We excluded apps that targeted general wellness, apps which focused on prevention of psychological disorders and apps that targeted bipolar disorder, psychosis, post-traumatic stress disorder, attention-deficit hyperactivity disorder, substance use disorders (aside from alcohol), and sleep disorders. Eligible comparisons included usual care, no intervention, wait-list control, alternative or controlled mobile applications. We included studies which reported outcomes on depressive symptoms, anxiety symptoms, alcohol use and psychological distress over any follow-up period.

Data Collection and Analysis
We standardized the PICO definitions (population, intervention, comparison, and outcome) of each included study and grouped studies by the type of therapy or support offered by the app. Whenever app design and clinical homogeneity allowed, we meta-analyzed outcomes using a random-effects model. Outcome data measured using categorical scales were synthesized using odds ratios. Outcome data measured using continuous scales were synthesized as the standardized mean difference. We assessed the methodological quality of each included study using the Cochrane Risk of Bias 2.0 tool and we assessed certainty of the evidence using the GRADE approach.

Main Results
From 5280 unique citations, we included 36 RCTs published in 37 reports and conducted in 15 different countries (7984 participants). Among the 36 included trials, we assessed two with an overall low risk of bias, 8 trials with some concern regarding risk of bias, and 26 trials with a high risk of bias. Interventions varied in the type of therapy or supports offered. The most common intervention designs employed mindfulness training, cognitive behavioral therapy (CBT), or a combination of the two (mindfulness&thinsp;+&thinsp;CBT). However, other interventions also included self-monitoring, medication reminders, cognitive bias modification or positive stimulation, dialectical behavioral therapy, gamified health promotion, or social skill building. Mindfulness apps led to short term improvements in depressive symptoms when compared to a withheld control (SMD&thinsp;=&thinsp;&minus;0.36; 95% CI [&minus;0.63, &minus;0.10]; p&thinsp;=&thinsp;0.007, n&thinsp;=&thinsp;3 RCTs, GRADE: very low certainty) and when compared to an active control (SMD&thinsp;=&thinsp;&minus;0.27; 95% CI [&minus;0.53, &minus;0.01]; p&thinsp;=&thinsp;0.04, n&thinsp;=&thinsp;2 RCTs, GRADE: very low). Apps delivering this type of support also significantly improved symptoms of anxiety when compared to a withheld control (SMD&thinsp;=&thinsp;&minus;0.35; 95% CI [&minus;0.60, &minus;0.09]; p&thinsp;=&thinsp;0.008, n&thinsp;=&thinsp;3 RCTs, GRADE: very low) but not when compared to an active control (SMD&thinsp;=&thinsp;&minus;0.24; 95% CI [&minus;0.50, 0.02]; p&thinsp;=&thinsp;0.07, n&thinsp;=&thinsp;2 RCTs, GRADE: very low). Mindfulness apps showed improvements in psychological stress that approached statistical significance among participants receiving the mindfulness mobile apps compared to those in the withheld control (SMD&thinsp;=&thinsp;&minus;0.27; 95% CI [&minus;0.56, 0.03]; p&thinsp;=&thinsp;.07, n&thinsp;=&thinsp;4 RCTs, GRADE: very low). CBT apps also led to short-term improvements in depressive symptoms when compared to a withheld control (SMD&thinsp;=&thinsp;&minus;0.40; 95% CI [&minus;0.80, 0.01]; p&thinsp;=&thinsp;0.05, n&thinsp;=&thinsp;2 RCTs, GRADE: very low) and when compared to an active control (SMD&thinsp;=&thinsp;&minus;0.59; 95% CI [&minus;0.98, &minus;0.19]; p&thinsp;=&thinsp;0.003, n&thinsp;=&thinsp;2 RCTs, GRADE: very low). CBT-based apps also improved symptoms of anxiety compared to a withheld control (SMD&thinsp;=&thinsp;&minus;0.51; 95% CI [&minus;0.94, &minus;0.09]; p&thinsp;=&thinsp;0.02, n&thinsp;=&thinsp;3 RCTs, GRADE: very low) but not when compared to an active control (SMD&thinsp;=&thinsp;&minus;0.26; 95% CI [&minus;1.11, 0.59]; p&thinsp;=&thinsp;0.55, n&thinsp;=&thinsp;3 RCTs, GRADE: very low). Apps which combined mindfulness and CBT did not significantly improve symptoms of depression (SMD&thinsp;=&thinsp;&minus;0.20; 95% CI [&minus;0.42, 0.02]; p&thinsp;=&thinsp;0.07, n&thinsp;=&thinsp;2 RCTs, GRADE: very low) or anxiety (SMD&thinsp;=&thinsp;&minus;0.21; 95% CI [&minus;0.49, 0.07]; p&thinsp;=&thinsp;0.14, n&thinsp;=&thinsp;2 RCTs, GRADE: very low). However, these apps did improve psychological distress (SMD&thinsp;=&thinsp;&minus;0.43; 95% CI [&minus;0.74, &minus;0.12]; p&thinsp;=&thinsp;0.006, n&thinsp;=&thinsp;2 RCTs, GRADE: very low). The results of trials on apps to reduce alcohol use were inconsistent. We did not identify any harms associated with the use of apps to manage mental health concerns. All effectiveness results had a very low certainty of evidence rating using the GRADE approach, meaning that apps which deliver therapy or other mental health support may reduce symptoms of depression, anxiety and psychological distress but the evidence is very uncertain.

Authors&#039; Conclusions
We reviewed evidence from 36 trials conducted among youth. According to our meta-analyses, the evidence is very uncertain about the effect of apps on depression, anxiety, psychological distress, and alcohol use. Very few effects were interpreted to be of clinical importance. Most of the RCTs were small studies focusing on efficacy for youth at risk for depressive symptoms. Larger trials are needed to evaluate effectiveness and allow for further analysis of subgroup differences. Longer trials are also needed to better estimate the clinical importance of these apps over the long term.
AU  - Magwood,
AU  - O.
AU  - Saad,
AU  - A.
AU  - Ranger,
AU  - D.
AU  - Volpini,
AU  - K.
AU  - Rukikamirera,
AU  - F.
AU  - Haridas,
AU  - R.
AU  - Sayfi,
AU  - S.
AU  - Alexander,
AU  - J.
AU  - Tan,
AU  - Y.
AU  - Pottie,
AU  - K.
DB  - April 24.enl
DO  - /10.1002/cl2.1398
L1  - internal-pdf://3351393682/Campbell Systematic Reviews - 2024 - Magwood -.pdf
PY  - 2024
T2  - Campbell Systematic Reviews
TI  - Mobile apps to reduce depressive symptoms and alcohol use in youth: A systematic review and meta-analysis: A systematic review
ER  -
TY  - JOUR
AB  - **Background**
Whole-school interventions modify the school environment to promote health. A subset of these interventions promotes student commitment to school to prevent substance (tobacco, alcohol, other drugs) use and/or violence. A previous review identified the theory of human functioning and school organisation as a comprehensive theory of such interventions, and found evidence that these interventions reduce substance use and/or violence.

**Objectives**
The objectives were to search for, appraise and synthesise evidence to address the following questions: (1) What whole-school interventions promoting student commitment to school to prevent substance use and/or violence have been evaluated, what intervention subtypes are apparent and how closely do these align with the theory of human functioning and school organisation? (2) What factors relating to setting, population and intervention affect implementation? (3) What are the effects on student substance use, violence and educational attainment? (4) What is the cost-effectiveness of such interventions? (5) Are intervention effects mediated by student commitment to school or moderated by setting or population?

**Data sources**
A total of 56 information sources were searched (in January 2020), then an updated search of 48 of these was carried out (in May 2021). Reference lists were also searched and experts were contacted.

**Review methods**
Eligible studies were process/outcome evaluations of whole-school interventions to reduce student violence or substance use among students aged 5&ndash;18 years attending schools, via actions aligning with the theory of human functioning and school organisation: modifying teaching to increase engagement, enhancing student&ndash;staff relationships, revising school policies, encouraging volunteering or increasing parental involvement. Data extraction and quality assessments used existing tools. Theory and process reports were synthesised qualitatively. Outcome and economic data were synthesised narratively; outcome data were meta-analysed.

**Results**
Searches retrieved 63 eligible reports on 27 studies of 22 interventions. We identified four intervention subtypes focused on student participation in school-wide decisions, improving staff&ndash;student relationships, increasing engagement in learning and involving parents. The theories of change of most intervention subtypes aligned closely with the theory of human functioning and school organisation, and informed refinement of an intervention theory of change. Theories of change for interventions increasing learning engagement did not align with this theory, aiming instead to increase school commitment primarily via social skills curricula. Factors influencing the implementation included whether or not interventions were tailorable, workable and well explained. Interventions with action groups comprising staff/students, etc. and providing local data were well implemented. Implementation was also affected by whether or not schools accepted the need for change and staff had the resources for delivery. Meta-analyses suggest small, but significant, intervention effects in preventing violence victimisation and perpetration, and substance use. There was sparse and inconsistent evidence of moderation and some evidence of mediation by student commitment to school. Two economic evaluations suggested that there is the potential for the interventions to be cost-effective.

**Limitations**
The quality of the studies was variable and the economic synthesis was limited to two studies.

**Conclusions**
Whole-school interventions aiming to promote student commitment to school share similar theories of change and factors affecting implementation. They have the potential to contribute to preventing violence and substance use among young people. Future trials should aim to optimise intervention effectiveness by better theorisation, and assess implementation and effect moderators and mediators.
AN  - 38356404
AU  - Ponsford,
AU  - R.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Miners,
AU  - A.
AU  - Falconer,
AU  - J.
AU  - Bonell,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3310/DWTR3299
L1  - internal-pdf://3433316594/Ponsford-2024-Whole-school interventions promo.pdf
PY  - 2024
SP  - 1-290
T2  - Public Health Research
TI  - Whole-school interventions promoting student commitment to school to prevent substance use and violence, and improve educational attainment: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38356404
UR  - https://njl-admin.nihr.ac.uk/document/download/2044790
VL  - 12
ER  -
TY  - JOUR
AB  - The occurrence of preterm birth is correlated with the potential emergence of disabilities in children. Early intervention programs are designed to promote better developmental outcomes. These interventions employ family-centered methodologies, wherein parents are instructed to facilitate neurodevelopment, thereby promoting heightened involvement of the child in their daily activities. The objective of this investigation was to evaluate the efficacy of early family-based interventions on motor, cognitive, and language development. A systematic review and meta-analysis was conducted utilizing the databases PubMed, Medline, PEDro, Scopus, CINAHL Complete, SciELO, and Open Grey. The search terms utilized included NDT (neuro-developmental treatment), Bobath, neurodevelopmental therapy, parents administered, family administered, physical therapy modalities, early intervention (educational), early intervention, premature infant, preterm, and premature. Randomized clinical trials and observational studies written in English or Spanish were taken into consideration. The initial search resulted in 420 articles. After removing duplicates and applying the selection criteria, 12 articles were selected for the systematic review and 5 articles were selected for the meta-analysis. The meta-analysis revealed a significant association between early intervention and enhanced cognitive function (p = 0.01) in this study. Additionally, the meta-analysis indicated improvements resulting from early family-based intervention (p = 0.02) in motor function. Early motor interventions that emphasize parent involvement and education in neurodevelopment show significant outcomes in motor and cognitive areas at 2 years of age in very premature or extremely premature infants. However, inconclusive effects have been found in the language area, which is the least studied domain. Due to the methodological heterogeneity observed, further research is needed to establish conclusive decisions regarding the administration of these interventions and the determination of key evaluation periods.
AN  - 39028424
AU  - Bernabe-Zuniga,
AU  - J.
AU  - E.
AU  - Rodriguez-Lucenilla,
AU  - M.
AU  - I.
AU  - Alias-Castillo,
AU  - A.
AU  - J.
AU  - Rueda-Ruzafa,
AU  - L.
AU  - Roman,
AU  - P.
AU  - Del
AU  - Mar
AU  - Sanchez-Joya,
AU  - M.
DB  - Juli 2024.enl
DO  - /10.1007/s00787-024-02528-1
L1  - internal-pdf://3449240612/Bernabe-Zuniga-2024-Early interventions with p.pdf
PY  - 2024
SP  - 19
T2  - European Child &amp; Adolescent Psychiatry
TI  - Early interventions with parental participation and their implications on the neurodevelopment of premature children: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1007%2fs00787-024-02528-1
UR  - https://link.springer.com/article/10.1007/s00787-024-02528-1
UR  - https://link.springer.com/content/pdf/10.1007/s00787-024-02528-1.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - BACKGROUND: Social anxiety disorder (SAD) is a high-prevalence mental disorder among children and adolescents. The aim of this study is to compare and rank the effectiveness of several psychotherapies for SAD among children and adolescents. 

METHODS: Only randomized controlled trials (RCTs) were utilized by searching PubMed, Embase, Cochrane Library, and Web of Science. We used network meta-analysis in the Bayesian framework to analyze the data. This study is registered with PROSPERO, number CRD42023476829. 

RESULTS: In total, 30 RCTs with 1547 individuals were included, and nine psychotherapies with three control conditions were compared and ranked in this study. The findings revealed that internet-delivered cognitive behavioural therapy (surface under the cumulative ranking curve [SUCRA: 71.2%]), group cognitive behavioural therapy (SUCRA: 68.4%), and individual cognitive behavioural therapy (SUCRA: 66.0%) significantly reduced social anxiety symptoms; internet-delivered cognitive behavioural therapy also significantly decreased depression symptoms in these patients (SUCRA: 92.2%). In addition, group cognitive behavioural therapy can enhance functioning in these patients (SUCRA: 89.6%). 

CONCLUSION: These results suggest that internet-delivered cognitive behavioural therapy is the optimal type of psychotherapy for reducing social anxiety and depression symptoms in children and adolescents with SAD, internet-delivered parent-child interaction therapy and cognitive bias modification of interpretation have relatively poor treatment effects on social anxiety symptoms in children than other psychological interventions, and group cognitive behavioural therapy has better benefits in enhancing the functioning among children and adolescents with SAD. Further studies are needed to ascertain these results due to the limited number of included studies.
AN  - 39173929
AU  - Xian,
AU  - J.
AU  - Zhang,
AU  - Y.
AU  - Jiang,
AU  - B.
DB  - August 2024.enl
DO  - /10.1016/j.jad.2024.08.097
L1  - internal-pdf://4146027531/1-s2.0-S0165032724013156-main.pdf
PY  - 2024
SP  - 20
T2  - Journal of Affective Disorders
TI  - Psychological interventions for social anxiety disorder in children and adolescents: A systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jad.2024.08.097
VL  - 20
ER  -
TY  - JOUR
AB  - Magnesium sulphate is a common therapy in perinatal care. Its benefits when given to women at risk of preterm birth for fetal neuroprotection (prevention of cerebral palsy for children) were shown in a 2009 Cochrane review. Internationally, use of magnesium sulphate for preterm cerebral palsy prevention is now recommended practice. As new randomised controlled trials (RCTs) and longer‐term follow‐up of prior RCTs have since been conducted, this review updates the previously published version.ObjectivesTo assess the effectiveness and safety of magnesium sulphate as a fetal neuroprotective agent when given to women considered to be at risk of preterm birth.Search methodsWe searched Cochrane Pregnancy and Childbirth&#039;s Trials Register, ClinicalTrials.gov, and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) on 17 March 2023, as well as reference lists of retrieved studies.Selection criteriaWe included RCTs and cluster‐RCTs of women at risk of preterm birth that assessed prenatal magnesium sulphate for fetal neuroprotection compared with placebo or no treatment. All methods of administration (intravenous, intramuscular, and oral) were eligible. We did not include studies where magnesium sulphate was used with the primary aim of preterm labour tocolysis, or the prevention and/or treatment of eclampsia.Data collection and analysisTwo review authors independently assessed RCTs for inclusion, extracted data, and assessed risk of bias and trustworthiness. Dichotomous data were presented as summary risk ratios (RR) with 95% confidence intervals (CI), and continuous data were presented as mean differences with 95% CI. We assessed the certainty of the evidence using the GRADE approach.Main resultsWe included six RCTs (5917 women and their 6759 fetuses alive at randomisation). All RCTs were conducted in high‐income countries. The RCTs compared magnesium sulphate with placebo in women at risk of preterm birth at less than 34 weeks&#039; gestation; however, treatment regimens and inclusion/exclusion criteria varied. Though the RCTs were at an overall low risk of bias, the certainty of evidence ranged from high to very low, due to concerns regarding study limitations, imprecision, and inconsistency.Primary outcomes for infants/children:Up to two years&rsquo; corrected age, magnesium sulphate compared with placebo reduced cerebral palsy (RR 0.71, 95% CI 0.57 to 0.89; 6 RCTs, 6107 children; number needed to treat for additional beneficial outcome (NNTB) 60, 95% CI 41 to 158) and death or cerebral palsy (RR 0.87, 95% CI 0.77 to 0.98; 6 RCTs, 6481 children; NNTB 56, 95% CI 32 to 363) (both high‐certainty evidence). Magnesium sulphate probably resulted in little to no difference in death (fetal, neonatal, or later) (RR 0.96, 95% CI 0.82 to 1.13; 6 RCTs, 6759 children); major neurodevelopmental disability (RR 1.09, 95% CI 0.83 to 1.44; 1 RCT, 987 children); or death or major neurodevelopmental disability (RR 0.95, 95% CI 0.85 to 1.07; 3 RCTs, 4279 children) (all moderate‐certainty evidence). At early school age, magnesium sulphate may have resulted in little to no difference in death (fetal, neonatal, or later) (RR 0.82, 95% CI 0.66 to 1.02; 2 RCTs, 1758 children); cerebral palsy (RR 0.99, 95% CI 0.69 to 1.41; 2 RCTs, 1038 children); death or cerebral palsy (RR 0.90, 95% CI 0.67 to 1.20; 1 RCT, 503 children); and death or major neurodevelopmental disability (RR 0.81, 95% CI 0.59 to 1.12; 1 RCT, 503 children) (all low‐certainty evidence). Magnesium sulphate may also have resulted in little to no difference in major neurodevelopmental disability, but the evidence is very uncertain (average RR 0.92, 95% CI 0.53 to 1.62; 2 RCTs, 940 children; very low‐certainty evidence).Secondary outcomes for infants/children: Magnesium sulphate probably reduced severe intraventricular haemorrhage (grade 3 or 4) (RR 0.76, 95% CI 0.60 to 0.98; 5 RCTs, 5885 infants; NNTB 92, 95% CI 55 to 1102; moderate‐certainty evidence) and may have resulted in little to no difference in chronic lung disease/bronchopulmonary dysplasia (average RR 0.92, 95% CI 0.77 to 1.10; 5 RCTs, 6689 infants; low‐certainty evidence).Primary outcomes for women: Magnesium sulphate may have resulted in little or no difference in severe maternal outcomes potentially related to treatment (death, cardiac arrest, respiratory arrest) (RR 0.32, 95% CI 0.01 to 7.92; 4 RCTs, 5300 women; low‐certainty evidence). However, magnesium sulphate probably increased maternal adverse effects severe enough to stop treatment (average RR 3.21, 95% CI 1.88 to 5.48; 3 RCTs, 4736 women; moderate‐certainty evidence).Secondary outcomes for women: Magnesium sulphate probably resulted in little to no difference in caesarean section (RR 0.96, 95% CI 0.91 to 1.02; 5 RCTs, 5861 women) and postpartum haemorrhage (RR 0.94, 95% CI 0.80 to 1.09; 2 RCTs, 2495 women) (both moderate‐certainty evidence). Breastfeeding at hospital discharge and women&rsquo;s views of treatment were not reported.Authors&#039; conclusionsThe currently available evidence indicates that magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus, compared with placebo, reduces cerebral palsy, and death or cerebral palsy, in children up to two years&#039; corrected age, and probably reduces severe intraventricular haemorrhage for infants. Magnesium sulphate may result in little to no difference in outcomes in children at school age.While magnesium sulphate may result in little to no difference in severe maternal outcomes (death, cardiac arrest, respiratory arrest), it probably increases maternal adverse effects severe enough to stop treatment.Further research is needed on the longer‐term benefits and harms for children, into adolescence and adulthood. Additional studies to determine variation in effects by characteristics of women treated and magnesium sulphate regimens used, along with the generalisability of findings to low‐ and middle‐income countries, should be considered.
AN  - CD004661
AU  - Shepherd,
AU  - E.
AU  - S.
AU  - Goldsmith,
AU  - S.
AU  - Doyle,
AU  - L.
AU  - W.
AU  - Middleton,
AU  - P.
AU  - Marret,
AU  - S.
AU  - Rouse,
AU  - D.
AU  - J.
AU  - Pryde,
AU  - P.
AU  - Wolf,
AU  - H.
AU  - T.
AU  - Crowther,
AU  - C.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.1002/14651858.CD004661.pub4
KW  - *Bias
KW  - *Cerebral Palsy [prevention &amp; control]
KW  - *Magnesium Sulfate [adverse effects, therapeutic use]
KW  - *Neuroprotective Agents [therapeutic use]
KW  - *Premature Birth [prevention &amp; control]
KW  - *Randomized Controlled Trials as Topic
KW  - Female
KW  - Humans
KW  - Infant, Newborn
KW  - Pregnancy
KW  - Tocolytic Agents [therapeutic use]
L1  - internal-pdf://3877332850/Shepherd_et_al-2024-Cochrane_Database_of_Syste.pdf
N1  - [Pregnancy and Childbirth]
PY  - 2024
T2  - Cochrane Database of Systematic Reviews
TI  - Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus
UR  - http://dx.doi.org/10.1002/14651858.CD004661.pub4
ER  -
TY  - JOUR
AB  - The scientific and technological advances in the 21st century necessitate the acquisition of STEM skills for all students in order to be successful in post-secondary education and the workforce, including students with autism spectrum disorder (ASD). Technology-mediated intervention has shown promise in improving the STEM skills of students with ASD. This meta-analysis aimed to provide a quantitative synthesis of single-case experimental studies of technology-mediated interventions on the STEM achievement of students with ASD. Forty-four studies were included, and the Tau-U effect size (ES) across studies ranged from 0.28 to 1.00, with an omnibus ES of 0.91 (CI95 = [0.86, 0.97]). Variables such as technological devices and STEM areas acted as moderators. Implications for research and practice are discussed. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2025-32983-001
AU  - Zeng,
AU  - Yingying
AU  - Liu,
AU  - Di
AU  - Mao,
AU  - Yiwen
AU  - Kang,
AU  - Rui
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1080/09362835.2024.2409078
L1  - internal-pdf://2716142874/Zeng-2024-Technology-mediated stem interventio.pdf
PY  - 2024
SP  - No Pagination Specified
T2  - Exceptionality
TI  - Technology-mediated stem interventions for students with autism spectrum disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.1080%2f09362835.2024.2409078
UR  - https://www.tandfonline.com/doi/pdf/10.1080/09362835.2024.2409078
ER  -
TY  - JOUR
AB  - Purpose:
The objective of this study was to do a meta-analysis focusing on the efficacy of psychological intervention for the adolescent population and PTSD as a primary outcome variable.

Collection and Analysis of Data:
An electronic search was conducted on PubMed, Science Direct, PsycINFO, and Cochrane Library databases from January 1, 1990, to March 31, 2023. Original studies and systematic reviews/meta-analyses were segregated. In the first study, 129 meta-analyses (MAs) were screened and 8 MAs were analyzed. In the second study, six RCTs and five non-RCTs exclusively including adolescents with a primary diagnosis of PTSD were analyzed. The MA revealed the average sample size to be 243.33 (SD = 372.94) with 63.98% female participants in RCTs and 153 (SD = 237.17) with 56.99% female participants in non-RCTs. A total of 13 different interventions were analyzed. Cognitive-behavioral intervention had a large effect size of 1.63 for PTSD. Cochrane&rsquo;s Q test and I2 index revealed considerable heterogeneity among groups. There was no significant difference between RCTs and non-RCTs in the total number and duration of intervention sessions and the duration of each session. However, the average follow-up time points varied significantly between RCTs and non-RCTs. RCTs followed random sequence generation and, hence, had a low risk of selection bias.

Conclusion:
Although the CBT framework with a focus on trauma and traumatic emotions was at the core of treatment efficacy, the type of trauma was the key consideration. Further studies of treatment efficacy moderated by specific trauma characteristics are required to advance the knowledge base in the treatment of PTSD in adolescents.
AN  - WOS:001246349900001
AU  - Arora,
AU  - S.
AU  - Satapathy,
AU  - S.
DB  - Juli 2024.enl
DO  - 10.1177/02537176241255643
L1  - internal-pdf://0316947976/arora-satapathy-2024-psychological-interventio.pdf
PY  - 2024
SP  - 14
T2  - Indian Journal of Psychological Medicine
TI  - Psychological Interventions for Post-traumatic Stress Disorder as a Primary Diagnosis Among Adolescents: A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001246349900001
UR  - https://journals.sagepub.com/doi/10.1177/02537176241255643
ER  -
TY  - JOUR
AB  - This meta-analysis aimed at investigating the therapeutic effects of probiotics against the symptoms of depression in children and adolescents as well as to identify the potential confounders. Following PRISMA guidelines, major databases were searched for randomized controlled trials focusing on effects of probiotics against the symptoms of depression in children and adolescents to analyze the effect size (ES) for primary outcomes (i.e., improvement in depressive symptoms) expressed as standardized mean difference (SMD) and odds ratios (ORs) for continuous and categorical variables, respectively, with 95% confidence interval (CI). Meta-analysis of five studies (692 participants, mean age = 7.33 years, treatment duration 8-104 weeks) demonstrated no significant improvement in depressive symptoms in subjects receiving probiotics (SMD = 0.04, 95% CI: -0.33 to 0.41, p = 0.84, five studies, 692 participants). Subgroup analysis also showed no significant improvement associated with probiotic use relative to controls in the subgroup of studies focusing on individuals diagnosed with neurodevelopmental disorders (SMD = -0.11, 95% CI: -0.73 to 0.51, p = 0.72, three studies, 452 participants) and that recruiting the general population (SMD = 0.24, 95% CI: -0.43 to 0.91, p = 0.48, two studies, 240 participants). However, high levels of heterogeneity were found in both our primary results (I2 = 77%, p = 0.001) and subgroup analyses for those with neurodevelopmental disorders (I2 = 84%, p = 0.002) and the general population (I2 = 79%, p = 0.03). The results did not support the use of probiotics for relieving depressive symptoms compared with controls in children and adolescents diagnosed with neurodevelopmental disorders or in the general population. Nevertheless, given the high level of heterogeneity across the included trials and a lack of studies focusing on those with diagnoses of anxiety or depression in the current meta-analysis, further large-scale clinical investigations are required to elucidate the therapeutic potential of probiotics against depressive symptoms in these populations, especially in those diagnosed with neurodevelopmental disorders or depression.
AN  - WOS:001351582500001
AU  - Chen,
AU  - C.
AU  - M.
AU  - Liang,
AU  - S.
AU  - C.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Tang,
AU  - Y.
AU  - H.
AU  - Liu,
AU  - C.
AU  - Hung,
AU  - K.
AU  - C.
DB  - November 2024.enl
DO  - 10.1186/s13052-024-01807-6
L1  - internal-pdf://3909188116/Chen-2024-Therapeutic effects of probiotics on.pdf
PY  - 2024
SP  - 9
T2  - Italian Journal of Pediatrics
TI  - Therapeutic effects of probiotics on symptoms of depression in children and adolescents: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001351582500001
UR  - https://ijponline.biomedcentral.com/counter/pdf/10.1186/s13052-024-01807-6.pdf
VL  - 50
ER  -
TY  - JOUR
AB  - OBJECTIVE: To investigate the efficacy of physical activity as a crucial intervention for Autism spectrum disorder (ASD) in clinical settings, we conducted a network meta-analysis to evaluate the effect of various exercise interventions on sociability and communication in individuals with ASD. Our aim was to identify the exercise modalities most conducive to enhancing these essential skills. 

METHODS: We searched Web of Science, PubMed, Cochrane Library, Scopus, Embase, and searched Chinese databases from inception to April 2024. We included randomized controlled trials that assessed the effects of different exercise types on sociability and communication in individuals with ASD. Network meta-analysis (NMA) was performed using a frequentist approach, and the node-splitting method was applied to assess inconsistency. 

RESULTS: We included 38 original studies published between 2009 and 2024, with a total of 1,382 participants analyzed for sociability outcomes. Results indicated that sports games [SMD = 1.12, 95%CI (0.51, 1.73)], combination therapy [SMD = 1.11, 95%CI (0.13, 2.09)], group ball sports [SMD = 1.06, 95%CI (0.37, 1.75)], and outdoor exercise [SMD = 1.02, 95%CI (0.50, 1.55)] were more effective than passive controls. A total of 25 original literatures were included in the analysis of communication ability, involving 904 subjects, and the results showed that combination therapy [SMD = 1.57, 95% CI (0.74, 2.40)], sports games [SMD = 1.01, 95% CI (0.45, 1.56)], group ball games [SMD = 0.85, 95% CI (0.45, 1.26)], outdoor exercise [SMD = 0.79, 95% CI (0.48, 1.11)], and mind-body exercise [SMD = 0.79, 95% CI (0.29, 1.30)], all of which were more effective than passive controls. 

CONCLUSION: Physical exercise plays a significant role in alleviating symptoms and enhancing sociability and communication in individuals with ASD. Our findings highlight that sports games, combination therapy, team ball sports, and outdoor exercise are particularly effective in improving sociability. In terms of communication skills, combination therapy, sports games, team ball sports, outdoor exercise, and mind-body exercise demonstrated the most substantial benefits. These results provide a robust foundation for future interventions aimed at improving the quality of life for individuals with ASD.
AN  - 39614353
AU  - Kou,
AU  - R.
AU  - Li,
AU  - Z.
AU  - Li,
AU  - M.
AU  - Zhou,
AU  - R.
AU  - Zhu,
AU  - F.
AU  - Ruan,
AU  - W.
AU  - Zhang,
AU  - J.
DB  - Desember 2024.enl
DO  - /10.1186/s40359-024-02210-w
L1  - internal-pdf://2227370514/Kou-2024-Comparative effectiveness of physical.pdf
PY  - 2024
SP  - 712
T2  - BMC psychology
TI  - Comparative effectiveness of physical exercise interventions on sociability and communication in children and adolescents with autism: a systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1186%2fs40359-024-02210-w
UR  - https://bmcpsychology.biomedcentral.com/counter/pdf/10.1186/s40359-024-02210-w.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - This study employed a meta-analytic approach to examine the effectiveness of graphic organizers (GOs) in improving academic and behavioral outcomes for K-12 students with disabilities, drawing from the single-case special education literature. Moderators at participant and study level were analyzed in addition to the main effects. A comprehensive search yielded 47 studies that met the inclusion criteria, making data available on 184 participants and 5,065 repeated measures. Employing a multivariate multilevel meta-analysis, the present study explored the efficacy of GO interventions while considering various moderators at the participant and study levels. The findings revealed that use of GOs is an effective strategy for enhancing academic performance among students with disabilities, including those with learning disabilities and various other disabilities, across multiple academic domains. However, despite the large number of studies included in the meta-analysis, only limited conclusions can be drawn with respect to the differential effectiveness of GO interventions, since the papers focused primarily on language skill acquisition, and many did not adequately document the moderators. Recommendations include future research addressing these limitations. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2025-18787-001
AU  - Urton,
AU  - Karolina
AU  - Moeyaert,
AU  - Mariola
AU  - Nobel,
AU  - Kerstin
AU  - Barwasser,
AU  - Anne
AU  - Boon,
AU  - Richard
AU  - T.
AU  - Grunke,
AU  - Matthias
DB  - September 2024.enl
DO  - /10.1080/09362835.2024.2389080
L1  - internal-pdf://1845383955/Effects of Graphic Organizers on Outcomes for.pdf
PY  - 2024
SP  - No Pagination Specified
T2  - Exceptionality
TI  - Effects of graphic organizers on outcomes for students with disabilities: Three-level meta-analysis of single-case studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.1080%2f09362835.2024.2389080
ER  -
TY  - JOUR
AB  - Objective: Externalizing behavior concerns (EBCs) are a common concern among youth and can be associated with significant problems, indicating the need for effective treatment. While research on psychosocial interventions is promising, the specific efficacy of youth group therapy has not been assessed in a meta-analysis. The aim of this study was to assess group therapy&#039;s efficacy for EBCs and evaluate treatment moderators. Impact Statement Youth with behavioral problems who participate in group therapy show a reduction in problem behaviors as well as other improvements. This research suggests that group therapy is effective in treating behavioral concerns. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2025-09085-001
AU  - Arnold,
AU  - Rachel
AU  - A.
AU  - Burlingame,
AU  - Gary
AU  - M.
AU  - Rosendahl,
AU  - Jenny
DB  - August 2024.enl
DO  - /10.1037/gdn0000225
L1  - internal-pdf://1205364112/2025-09085-001.cleaned.pdf
PY  - 2024
SP  - No Pagination Specified
T2  - Group Dynamics: Theory, Research, and Practice
TI  - Group therapy for youth behavioral concerns: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.1037%2fgdn0000225
ER  -
TY  - JOUR
AB  - **CONTEXT**: 
Effective treatment of attention-deficit/hyperactivity disorder (ADHD) is essential to improving youth outcomes. 

**OBJECTIVES**: 
This systematic review provides an overview of the available treatment options. 

**DATA SOURCES**: 
We identified controlled treatment evaluations in 12 databases published from 1980 to June 2023; treatments were not restricted by intervention content. 

**STUDY SELECTION**: 
Studies in children and adolescents with clinically diagnosed ADHD, reporting patient health and psychosocial outcomes, were eligible. Publications were screened by trained reviewers, supported by machine learning. 

**DATA EXTRACTION**: 
Data were abstracted and critically appraised by 1 reviewer and checked by a methodologist. Data were pooled using random-effects models. Strength of evidence and applicability assessments followed Evidence-based Practice Center standards. 

**RESULTS**: 
In total, 312 studies reported in 540 publications were included. We grouped evidence for medication, psychosocial interventions, parent support, nutrition and supplements, neurofeedback, neurostimulation, physical exercise, complementary medicine, school interventions, and provider approaches. Several treatments improved ADHD symptoms. Medications had the strongest evidence base for improving outcomes, including disruptive behaviors and broadband measures, but were associated with adverse events. 

**LIMITATIONS**: 
We found limited evidence of studies comparing alternative treatments directly and indirect analyses identified few systematic differences across stimulants and nonstimulants. Identified combination of medication with youth-directed psychosocial interventions did not systematically produce better results than monotherapy, though few combinations have been evaluated. 

**CONCLUSIONS**: 
A growing number of treatments are available that improve ADHD symptoms and other outcomes, in particular for school-aged youth. Medication therapies remain important treatment options but are associated with adverse events.
AN  - 38523592
AU  - Peterson,
AU  - B.
AU  - S.
AU  - Trampush,
AU  - J.
AU  - Maglione,
AU  - M.
AU  - Bolshakova,
AU  - M.
AU  - Rozelle,
AU  - M.
AU  - Miles,
AU  - J.
AU  - Pakdaman,
AU  - S.
AU  - Brown,
AU  - M.
AU  - Yagyu,
AU  - S.
AU  - Motala,
AU  - A.
AU  - Hempel,
AU  - S.
DB  - Mars 24.enl
DO  - /10.1542/peds.2024-065787
L1  - internal-pdf://2924332730/Peterson-2024-Treatments for ADHD in Children.pdf
PY  - 2024
SP  - 01
T2  - Pediatrics
TI  - Treatments for ADHD in Children and Adolescents: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;DO=10.1542%2fpeds.2024-065787
UR  - https://watermark.silverchair.com/peds.2024-065787.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA04wggNKBgkqhkiG9w0BBwagggM7MIIDNwIBADCCAzAGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMNCoABIfQcFZsvGlAAgEQgIIDATzlZo_4wCqnhRD21ImnKRbs6zh09kVpglkGoKt6iDJdrqlZ1zpT4ghdDg4JGvwVhuWrZgE377iHLT0yugxHyut7pmTAr2k7JTYorNCQ4idF4gKfp3UcSubkT9sE9gwQSIzf7mr3MxdQJam8GCezruLZQRJdBfaWkOg2DAglQHR4umCJhlzeMiNEpPh_ukPA6p1CxCUKAVcKCOiXqs0bqO6hApM0wuaSiXYSsfhIfvzef5M7VVY-4eVuN6NyFTNpZv5qBcZrNx26mqHDXUffdrqQYDQRseTGqi5SDiGMaoaxzSgTb6j5mKYfbx9CzSSW2H0G3qGgil_El37EfAAd9mqZU4pKL0NrACu2tI_0GVFT02eRReN-6_asrWvG4Mn9Lj2u5IemkOhHIH5MyredRzux7bzgbyBMi-0aJbm6kgEFi-qvi7C4_gLvdqQVK96rUrI9MCojBmZfm4CVhopz-lmq9pBqN8H7v2-syAS495kdOWlLOUIanH3ImxZkHRhRrJd0xeYiW0eqgJDEcUZGrIAgUlt6zFwPe17noCMEbuI2r7At5T0zUHneVxY3xUuRpnX6gNqNzAVtS-tvvwBnGT3lwYxE2edrdKkRRba76PEazuPAcfvmScyUZbh-CbbHeKNKSgx6JMfuz8wWgQrOyzkDj0Xcx2V1ZIayxfjR-YznhN1H7YGUTsanbZfM-R8kCTsQVSpa_owcyIqx48_Olf_3qLKxFmwZXXLnj_Cy7fpzuLpbk9EJYi4wycwoZYntk1XHFmFqnCOxfEgLXqAQEGMTPkoIq_EUAZmRkNzAbepD-QnVk62YbVL_AG9ihnPu0KSJ03-EDISf4B6XY2DdpADER_C1XVFURBQoncjgFiMAH3LDEFrrny1VxPXTCjBHWsbrRdi-656d7CUc6vetGebgXwSNjqQtnq22npZOS7iA4f_1tn81twehhOdbRtPq124Men8-FGtpgdbP4aNIw1by8LW5PDVojttq06kUt7n4rv3UUYhT_5_vU4VAPfUhFxI
VL  - 153
ER  -
TY  - JOUR
AB  - We conducted an overview of reviews to determine the effects of naturalistic developmental behavioral interventions (NDBIs; Schreibman et al. (2015) J Autism Dev Disorders 45:2411-2428) on children with autism spectrum disorder under 8 years old. We conducted an electronic database search of Academic Search Premier, CINHAL, ERIC, Medline, and APA PsycINFO in October 2022 and August 2023 and utilized snowball methods to locate relevant reviews of NDBI. We included reviews meeting the following inclusion criteria: (1) review included a meta-analytic synthesis for at least one child outcome; (2) primary studies examined a NDBI; (3) primary studies included children with ASD with a mean pre-treatment age under eight years; (4) primary studies were conducted using a two-group comparison design; and (5) review was published in English. We extracted data on characteristics of the review, participant characteristics from the primary studies, intervention characteristics, and assessed the risk of bias of the included reviews. We conducted a narrative synthesis across outcomes reported in the included reviews. We included five reviews from six reports in this overview. Two reviews included studies that examined the Early Start Denver Model, two reviews included studies that examined the Pivotal Response Treatment, and one review included studies examining NDBIs collectively. We found positive effects of NDBIs on child&#039;s communication/language, cognition, and adaptive behavior. We found mixed effects for NDBIs on autism symptomatology and restricted and repetitive behaviors. Examination of moderator analyses reported in the included reviews suggested variables influencing the effects of NDBIs included proximity of outcome to intervention, boundedness of outcome to intervention, and study location. As shown in this overview, positive effects of NDBI for young children with ASD are supported by meta-analytic evidence. While the overall findings for NDBI across reviews are positive, the findings on specific outcomes and influential variables moderating the effects of NDBI are inconsistent. Additional evidence from randomized controlled trials and future meta-analyses are needed to strengthen our knowledge of the effects of NDBI for young children with ASD.Protocol Registration: PROSPERO CRD42022353045.
AN  - WOS:001134147000001
AU  - Song,
AU  - J.
AU  - W.
AU  - Reilly,
AU  - M.
AU  - Reichow,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s10803-023-06198-x
L1  - internal-pdf://0751733595/Song-2024-Overview of Meta-Analyses on Natural.pdf
PY  - 2024
SP  - 13
T2  - Journal of Autism and Developmental Disorders
TI  - Overview of Meta-Analyses on Naturalistic Developmental Behavioral Interventions for Children with Autism Spectrum Disorder
UR  - &lt;Go to ISI&gt;://WOS:001134147000001
UR  - https://link.springer.com/article/10.1007/s10803-023-06198-x
UR  - https://link.springer.com/content/pdf/10.1007/s10803-023-06198-x.pdf
ER  -
TY  - JOUR
AB  - PURPOSE: Evidence on non-pharmacological interventions for adolescents with type 1 diabetes is unclear. This review aimed to evaluate the effectiveness of non-pharmacological intervention in adolescents with type 1 diabetes. 

METHODS: We conducted a search on databases from November 11 to 19, 2022, for randomized controlled trials for the effects of non-pharmacological intervention in adolescents with type 1 diabetes. To identify recent research trends, we included studies published from 2017 to November 2022. The risk of bias was assessed using the Cochrane risk-of-bias tool 2.0. To estimate the effect size, a meta-analysis was performed using RevMan 5.4 program and R Studio. 

RESULTS: A total of 45 studies were included in the systematic review. Among those, 30 studies were included in the meta-analysis. Non-pharmacological interventions were significantly effective in improving Glycated hemoglobin (HbA1c) (standardized mean difference [SMD] = -0.26, 95% confidence interval [CI]: -0.42, -0.09), quality of life (SMD = 0.44, 95% CI: 0.13 to 0.76), and anxiety (SMD = -0.91, 95% CI: -1.26, -0.56). Subgroup analysis showed that duration of intervention was not a covariate related to HbA1c levels. 

CONCLUSIONS: Non-pharmacological interventions have shown effectiveness in improving the HbA1c, quality of life, and anxiety in adolescents with type 1 diabetes. Future studies with more rigorous methodology are needed to confirm and strengthen the validity of these findings. Additionally, attention to changes in the lipid profile and self-care motivation among adolescents with type 1 diabetes is warranted.

TRIAL REGISTRATION NUMBER: Prospective Register of Systematic Reviews (CRD42022382190).
AN  - 38307162
AU  - Lee,
AU  - D.
AU  - Lee,
AU  - H.
AU  - Shin,
AU  - Y.
AU  - Park,
AU  - G.
DB  - Mars 24.enl
DO  - /10.1016/j.anr.2024.01.008
L1  - internal-pdf://2731132117/1-s2.0-S1976131724000082-main.cleaned.pdf
PY  - 2024
SP  - 51-59
T2  - Asian Nursing Research
TI  - Effectiveness of Non-pharmacological Interventions for Adolescents With Type 1 Diabetes in the Last Five Years: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1016%2fj.anr.2024.01.008
UR  - https://www.sciencedirect.com/science/article/pii/S1976131724000082?via%3Dihub
VL  - 18
ER  -
TY  - JOUR
AB  - Evidence on the effectiveness of cognitive behavioral therapy (CBT)-based interventions for mental health problems of children and adolescents in institutional/foster care has been presented in various studies. However, the literature does not contain a meta-analysis study that examines and synthesizes the results together. This study aimed to examine the effectiveness of CBT in the mental health problems of children and adolescents in foster and institutional care. In the literature review, we included eight studies that met the inclusion criteria in the analysis. The results showed CBT had a strong effect (g = 1.08) on improving the mental health problems of children and adolescents in institutional/foster care. The results also showed that CBT interventions were more effective in depression (g = 1.70) than anxiety (g = 0.87) in children and adolescents in institutional/foster care. Additionally, the results indicated that CBT-based interventions were more effective in groups consisting solely of children (g = 4.06) than in groups comprising children and adolescents (g = 1.70). Thus, this
AN  - WOS:001353404000001
AU  - Das,
AU  - H.
AU  - Kurnaz,
AU  - M.
AU  - F.
AU  - Ko&ccedil;t&uuml;rk,
AU  - N.
DB  - November 2024.enl
DO  - 10.1016/j.jbct.2024.100509
PY  - 2024
SP  - 10
T2  - Journal of Behavioral and Cognitive Therapy
TI  - The effectiveness of cognitive behavioral therapy in mental health problems of children and adolescents in child protection system: A meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001353404000001
UR  - https://www.sciencedirect.com/science/article/abs/pii/S2589979124000271?via%3Dihub
VL  - 34
ER  -
TY  - JOUR
AB  - BACKGROUND: Violence against children is a global phenomenon, yet children living in humanitarian settings are at elevated risk of experiencing violent parenting. Parenting interventions are a recommended prevention strategy. 

OBJECTIVE: To conduct a systematic review and meta-analysis on the effectiveness of parenting interventions in preventing violence against children and related parent and child outcomes. 

PARTICIPANTS AND SETTING: Primary caregivers in humanitarian settings in low- and middle-income countries (LMICs). 

METHODS: A highly sensitive multi-language systematic search in electronic and grey-literature database. Studies were appraised for risk of bias, summary effects by certainty of effect, and effect estimates pooled using robust variance estimation. 

RESULTS: Twenty-three randomized trials were meta-analyzed finding a small effect on physical and psychological violence (n = 14, k = 21, d = -0.36, 95 % CI [-0.69, -0.04]), positive parenting (n = 16, k = 43, d = 0.48, 95 % CI [0.29, 0.67]), negative parenting (n = 17, k = 37, d = -0.42, 95 % CI [-0.67, -0.16]), parental poor mental health (n = 9, k = 15, d = -0.34, 95 % CI [-0.66, -0.02]), and internalizing behaviors (n = 11, k = 29, d = -0.38, 95 % CI [-0.70, -0.05]); a non-significant effect on externalizing child behaviors (n = 9, k = 17, d = -0.12, 95 % CI [-0.50, 0.27]). Too few studies reported intimate partner violence, sexual violence, and parenting stress outcomes.

CONCLUSIONS: Our findings suggest that parenting interventions in humanitarian settings in LMICs may be an effective strategy to reduce physical and psychological violence, and numerous related parent and child outcomes. However, findings need to be interpreted in light of the limited number of available studies and imprecise statistical significance for selected outcomes.
AN  - 38880688
AU  - Backhaus,
AU  - S.
AU  - Blackwell,
AU  - A.
AU  - Gardner,
AU  - F.
DB  - Juni 24.enl
DO  - /10.1016/j.chiabu.2024.106850
L1  - internal-pdf://1832021383/1-s2.0-S0145213424002400-main.cleaned.pdf
PY  - 2024
SP  - 106850
T2  - Child Abuse &amp; Neglect
TI  - The effectiveness of parenting interventions in reducing violence against children in humanitarian settings in low- and middle-income countries: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.chiabu.2024.106850
ER  -
TY  - JOUR
AB  - Fidget devices are often used in classrooms to help students move their bodies while attending to academic or behavioral directives. Devices range from small handheld tools such as spinners and tangle puzzles to larger full-body devices such as exercise balls. The current study provides a meta-analysis of the effects of fidget devices as academic and behavioral interventions in single-case design studies. Ten studies with a total of 59 students were included in the analysis. Results indicate that the effects of fidget devices vary widely with Tau-BC effects ranging from -1.00 to 1.00 and log-response ratio (LRR) effects ranging from -1.37 to 2.18. There is an overall positive treatment effect with LRR = 0.32 (95% CI = [0.08, 0.56]) and Tau-BC = 0.33 (95% CI = [0.02, 0.64]). The only moderating variables were, when considering the Tau-BC effect size estimates, methodological rigor and intervention implementation; studies that met What Works Clearinghouse methodological standards and were implemented within group settings had significantly higher effects than those studies that did not meet standards. Discussion explores connections to behavior analytic and sensory integration therapies and implications for fidget devices as interventions in schools. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2025-36630-001
AU  - Schoenen,
AU  - Ella
AU  - C.
AU  - Martinez,
AU  - Julie
AU  - C.
AU  - Grekov,
AU  - Paulina
AU  - Aspiranti,
AU  - Kathleen
AU  - B.
AU  - Hulac,
AU  - David
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1007/s43494-024-00133-0
L1  - internal-pdf://1416365886/Schoenen-2024-Fidget devices as academic and b.pdf
PY  - 2024
SP  - No Pagination Specified
T2  - Education &amp; Treatment of Children
TI  - Fidget devices as academic and behavioral interventions: A meta-analysis of single-case design studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.1007%2fs43494-024-00133-0
UR  - https://link.springer.com/article/10.1007/s43494-024-00133-0
UR  - https://link.springer.com/content/pdf/10.1007/s43494-024-00133-0.pdf
ER  -
TY  - JOUR
AB  - **Introduction**: This study aimed to systematically review the effects of different physical activity programs on the fundamental movement skills of 3 - 7-year-old children. **Methods**: For this review, the databases of CNKI, Web of Science, and PubMed were searched to collect relevant literature on the effects of different physical activity program interventions on fundamental movement skills, and a total of 10 articles with 1,121 subjects were included. The Cochrane Risk of Bias Assessment Tool was used to assess the quality of the literature, and meta-analysis was performed using Review Manager 5.4 software. **Results**: Physical activity significantly influenced children&#039;s running ability, horizontal jump, dribbling the ball, kicking ability, catching ability, overhand throwing, striking a stationary ball, and dynamic balance. However, the intervention effect was insignificant for the hop and underhand throwing abilities. The intervention effects for running ability, horizontal jump, kicking ability, and catching ability were better at less than 12 weeks than at 12 weeks and above. In addition, an intervention duration of 90 min or more was better than less than 90 min for running ability and horizontal jump. **Conclusion**: Future research is recommended to focus on the common factors of the intervention effects of physical activity programs to develop more precise and effective intervention practices to further improve children&#039;s fundamental movement skill levels.
AN  - 39839417
AU  - Yang,
AU  - Y.
AU  - Mao,
AU  - X.
AU  - Li,
AU  - W.
AU  - Wang,
AU  - B.
AU  - Fan,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fpubh.2024.1489141
L1  - internal-pdf://3773667546/Yang-2024-A meta-analysis of the effect of phy.pdf
PY  - 2024
SP  - 1489141
T2  - Frontiers in Public Health
TI  - A meta-analysis of the effect of physical activity programs on fundamental movement skills in 3-7-year-old children
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.3389%2ffpubh.2024.1489141
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC11748295/pdf/fpubh-12-1489141.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **Importance**: Child maltreatment is associated with serious negative physical, psychological, and behavioral consequences. 

**Objective**: To review the evidence on primary care-feasible or referable interventions to prevent child maltreatment to inform the US Preventive Services Task Force. 

**Data Sources**: PubMed, Cochrane Library, and trial registries through February 2, 2023; references, experts, and surveillance through December 6, 2023.

**Study Selection**: English-language, randomized clinical trials of youth through age 18 years (or their caregivers) with no known exposure or signs or symptoms of current or past maltreatment. 

**Data Extraction and Synthesis**: Two reviewers assessed titles/abstracts, full-text articles, and study quality, and extracted data; when at least 3 similar studies were available, meta-analyses were conducted. 

**Main Outcomes and Measures**: Directly measured reports of child abuse or neglect (reports to Child Protective Services or removal of the child from the home); proxy measures of abuse or neglect (injury, visits to the emergency department, hospitalization); behavioral, developmental, emotional, mental, or physical health and well-being; mortality; harms. 

**Results**: Twenty-five trials (N = 14355 participants) were included; 23 included home visits. Evidence from 11 studies (5311 participants) indicated no differences in likelihood of reports to Child Protective Services within 1 year of intervention completion (pooled odds ratio, 1.03 [95% CI, 0.84-1.27]). Five studies (3336 participants) found no differences in removal of the child from the home within 1 to 3 years of follow-up (pooled risk ratio, 1.06 [95% CI, 0.37-2.99]). The evidence suggested no benefit for emergency department visits in the short term (&lt;2 years) and hospitalizations. The evidence was inconclusive for all other outcomes because of the limited number of trials on each outcome and imprecise results. Among 2 trials reporting harms, neither reported statistically significant differences. Contextual evidence indicated (1) widely varying practices when screening, identifying, and reporting child maltreatment to Child Protective Services, including variations by race or ethnicity; (2) widely varying accuracy of screening instruments; and (3) evidence that child maltreatment interventions may be associated with improvements in some social determinants of health. 

**Conclusion and Relevance**: The evidence base on interventions feasible in or referable from primary care settings to prevent child maltreatment suggested no benefit or insufficient evidence for direct or proxy measures of child maltreatment. Little information was available about possible harms. Contextual evidence pointed to the potential for bias or inaccuracy in screening, identification, and reporting of child maltreatment but also highlighted the importance of addressing social determinants when intervening to prevent child maltreatment.
AN  - 38502070
AU  - Viswanathan,
AU  - M.
AU  - Rains,
AU  - C.
AU  - Hart,
AU  - L.
AU  - C.
AU  - Doran,
AU  - E.
AU  - Sathe,
AU  - N.
AU  - Hudson,
AU  - K.
AU  - Ali,
AU  - R.
AU  - Jonas,
AU  - D.
AU  - E.
AU  - Chou,
AU  - R.
AU  - Zolotor,
AU  - A.
AU  - J.
DB  - Mars 24.enl
DO  - /10.1001/jama.2024.0276
L1  - internal-pdf://3591816811/Viswanathan-2024-Primary Care Interventions to.pdf
PY  - 2024
SP  - 959-971
T2  - JAMA
TI  - Primary Care Interventions to Prevent Child Maltreatment: Evidence Report and Systematic Review for the US Preventive Services Task Force
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;DO=10.1001%2fjama.2024.0276
UR  - https://watermark.silverchair.com/jama_viswanathan_2024_us_240001_1710362781.65711.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA1YwggNSBgkqhkiG9w0BBwagggNDMIIDPwIBADCCAzgGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMtWNDaBsW_H0xnQl6AgEQgIIDCehP6ZzxUap-1AxMFFZ1PG9j3LDlwZeDC1O5pFyR6pnBheP_AB191Kjv3CT4r_sC6xWxy1ANjE8aIX5vGc9bV2xf0K7MTaTMI_4L44sovdz0RYCE7pykxICKsaMwI_vmvKzjtLbLtPji2-Up68pmcC76iUAzTGJRWkb6muZGOSSann0WKtJwnYGrXGa55eHM5jrQ2Wb9Q_dGL_zjUVzG-Gx5Wj0-ITg1oYGLaclYjxBAtlmgtkjRjOdOVqFSLBizCmrF0hlzkdmMP6X6n1eyY-mg2KdMyxIt2pMBBreQryulXjWSRNTs7CYb-fxWR50yW-OxVDxHIpneCsvQjHxmqMnC_58Ci8TntccLlEiP9-zrZnHSHBete_vLBZqG4z_djzTwcyxD4GACfsxzzrqF1Cie2fzUQS6HgtvjwMc2kAbJ872l4SEmvfwrvpDAAs0Z91n9tFxi06kxOiNGcxYEmwN1TzY9C9Ojg3tg2PR_uKmYLUVyKFeRVGrrXhJifKTFynP5RUTvaA3FP7-jM9g9SJE9RsDX90i7zHQ1vY6LJaA3PF8dKX-eqSbvwpg2WK73RGVW6CqPaDFm6RbwDWyVO39eSNg_tvKDmxNngZ_myLhgBYBG76EgUjJV_Innd8r0q68-z5jxOknXXEYcQ90jZNKPQgvuNPhOp59BbhfSkAu43NX5Wi5T6jGnsJLIrmKFmjd0681mZiynFsgQRqsmtQSrXTd7ulWCDd0Zfi2lrEVgm3bTfhHyL07KiRTOo7IATpLJ8kXDPl89adGe05G2XYfhytqinYMZFu63t4SrEi2zShHhYkWUtqaCleSrce1ZeEmtWJAuSAq4iOJ9Td37U26orcLo_KWfB6DdRKXlULYsJSxaQ7sSnhirATZox7pblB_JA5NRjRGe1qggzjwQY0hYeXC_oqbHM2TijYJThwOZjqQ1Mx2ex1GeDZjutunX_KIn8cUd1_Pgd-FUs7uH_a2Z8p-9zAVAM9i51W-SJUGZZX82PaE-jq_AnVCYv4FQOMjzUIeDDGpzPw
VL  - 331
ER  -
TY  - JOUR
AB  - In previously randomized controlled trials (RCTs) on the efficacy of antidepressants in restricted and repetitive behaviors (RRBs) in autism spectrum disorder (ASD), outcomes overwhelmingly showed no benefits of antidepressants studied in the larger multisite RCTs over placebo. However, the positive effect of antidepressants in the RRBs found in the small preliminary studies requires confirmation in larger trials. We aimed to systematically review the efficacy of antidepressants in the treatment of RRBs in ASD by including RCTs from the SCOPUS, PubMed, Embase, Cochrane Controlled Trials Register, Clinical Trials.gov, and other databases in January 2024. Analyzing data from 609 participants across nine RCTs showed no significant difference in the overall pooled mean-end score for RRBs between antidepressant- and placebo-treated groups [SMD (95% CI) of -0.25 (-0.53, 0.02), I2 = 54%, Tau2 = 0.10, prediction interval = -1.03, 0.53]. In small preliminary studies by one group, the clomipramine-treated group&#039;s pooled mean endpoint for obsessive-compulsive symptoms in ASD individuals showed a significantly better outcome than the desipramine-treated group, but in unconfirmed studies. Of the individual antidepressants investigated only clomipramine, and fluvoxamine illustrated some efficacy over placebo in small preliminary studies. These findings need confirmation in larger, multisite randomized controlled trials. There were no significant differences in the overall discontinuation rates or discontinuation due to adverse events between the antidepressant- and placebo-treated groups [RR (95% CI) of 1.30 (0.95, 1.78), I2 = 0%, and 1.33 (0.71, 2.47), I2=0%, respectively]. Common side effects included agitation, appetite disturbance, anorexia, gastrointestinal issues, and sleep disturbance, with no significant differences between the antidepressant and placebo groups. In conclusion, the results regarding the efficacy of antidepressants in the treatment of RRBs in ASD are inconsistent. Since previous evidence found a correlation between attention-deficit hyperactivity disorder (ADHD) symptoms including overactivity and impulsivity, and RRBs, further trials including the use of non-stimulants such as atomoxetine could be conducted.
AN  - WOS:001409108300001
AU  - Maneeton,
AU  - P.
AU  - Maneeton,
AU  - B.
AU  - Winichaikul,
AU  - Y.
AU  - Kawilapat,
AU  - S.
AU  - Kienngam,
AU  - N.
AU  - Maneeton,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.2147/ndt.S465611
L1  - internal-pdf://2963740598/Maneeton-2024-Updated Systematic Review and Me.pdf
PY  - 2024
SP  - 1711-1723
T2  - Neuropsychiatric Disease and Treatment
TI  - Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials: Antidepressants for Restricted and Repetitive Behaviors in Autism Spectrum Disorder
UR  - &lt;Go to ISI&gt;://WOS:001409108300001
UR  - https://www.dovepress.com/article/download/96110
VL  - 20
ER  -
TY  - JOUR
AB  - Despite the pressing need for culturally responsive practices to ensure equitable outcomes for students from diverse backgrounds, there remains a lack of research on deliberate cultural considerations within evidence-based social and emotional learning (SEL) practices. In response, the current study seeks to explore evidence-based practices of culturally responsive SEL programs by reviewing literature published in the last ten years. A total of 13 studies were included in a qualitative systematic review. Among them, seven studies were incorporated in a quantitative meta-analysis. The authors investigated (a) for whom the programs were implemented, (b) by whom the programs were implemented, (c) how the programs were planned and implemented, and (d) for what the programs were implemented. The overall effect size (Hedge&#039;s g) was 0.36. The subgroup difference analyses were conducted by using participant-, implementer-, program-, and outcome-related variables as moderators. Although the subgroup differences were not statistically significant, programs implemented at the targeted level, led by researchers, used multiple culturally responsive strategies showed higher effect sizes than those implemented at the universal level, led by teachers, and used only one culturally responsive strategy. Based on the findings, implications for implementing culturally responsive SEL programs were provided.Impact StatementThe current study is the first attempt to systematically review empirical studies implementing culturally responsive SEL programs published in the last ten years. The findings inform the evidence-based practice of culturally responsive SEL programs, enabling educators to implement the most effective strategies. This study advocates for the expansion and rigorous evaluation of culturally responsive SEL practices to better address the unique needs of students from diverse sociocultural backgrounds.
AN  - WOS:001364578400001
AU  - Lim,
AU  - J.
AU  - H.
AU  - Rho,
AU  - E.
AU  - Yang,
AU  - C.
AU  - Y.
DB  - Desember 2024.enl
DO  - 10.1080/2372966x.2024.2432853
L1  - internal-pdf://3689675438/Lim-2024-Evidence-Based Practices of Culturall.pdf
PY  - 2024
SP  - 16
T2  - School Psychology Review
TI  - Evidence-Based Practices of Culturally Responsive Social and Emotional Learning (SEL) Programs: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001364578400001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/2372966X.2024.2432853
ER  -
TY  - JOUR
AB  - Dating violence (DV) is a social problem that affects adolescents worldwide. Previous systematic reviews have mainly examined universal prevention programs with varying designs and outcomes. The lack of systematic reviews focusing on at-risk adolescents limits knowledge about which interventions are more effective. This systematic review synthesizes studies of DV programs for at-risk adolescents. The following databases were searched: PsycINFO, Scopus, and Web of Science. A total of 5663 studies were identified; 17 were included in the systematic review and 11 in the meta-analysis. Randomized control trials and quasi-experimental studies with a follow-up longer than a month were included. When types of DV were analyzed separately, the results showed decreases in physical and sexual violence perpetration and physical DV victimization, but not significant changes in psychological and sexual violence victimization, psychological violence perpetration and attitudes toward DV were found. When composite scores were used (including all types of DV), significant reductions in DV victimization and perpetration were found. This systematic review and meta-analysis are the first to focus on atrisk adolescents and assess physical, psychological, sexual and cyber violence and attitudes toward DV. Examining existing programs is key to understanding what works for at-risk adolescents and improving their effectiveness.
AN  - WOS:001127126000001
AU  - Arrojo,
AU  - S.
AU  - Santirso,
AU  - F.
AU  - A.
AU  - Lila,
AU  - M.
AU  - Gracia,
AU  - E.
AU  - Conchell,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.avb.2023.101893
L1  - internal-pdf://2714922824/1-s2.0-S1359178923000800-main.cleaned.pdf
PY  - 2024
SP  - 18
T2  - Aggression and Violent Behavior
TI  - Dating violence prevention programs for at-risk adolescents: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001127126000001
UR  - https://www.sciencedirect.com/science/article/pii/S1359178923000800?via%3Dihub
VL  - 74
ER  -
TY  - JOUR
AB  - Young people who transition to adulthood from out-of-home care (OOHC) are more likely to experience a range of poorer outcomes relative to their same-age peers in the community. This systematic review assessed the effectiveness of policies or interventions (hereafter &quot;interventions&quot;) aimed at improving housing, health, education, economic, and psychosocial outcomes for youth leaving OOHC (hereafter &quot;care leavers&quot;). Eleven databases of published literature were reviewed along with gray literature. Eligible studies used randomized or quasi-experimental designs and assessed interventions that provided support to care leavers prior to, during, or after they left OOHC. Primary outcomes were housing and homelessness, health and well-being, education, economic and employment, criminal and delinquent behavior, and risky behavior, while secondary outcomes were supportive relationships and life skills. Where possible, results were pooled in a meta-analysis. Certainty of evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation. Fourteen studies published in 27 reports were identified that examined independent living programs (ILPs) (n = 5), intensive support services (n = 2), coaching and peer support (C&amp;PSP) (n = 2), transitional housing (n = 1), health information or coaching (n = 2), and extended care (n = 2). All but one study was conducted in the United States. Twenty small meta-analyses were undertaken encompassing ILPs and C&amp;PSP, with two showing results that favored the intervention with certainty. The level of confidence in each meta-analysis was considered very low. A significant risk of bias was identified in each of the included studies. While some interventions showed promise, particularly extended care, the scope and strength of included evidence is insufficient to recommend any included approach.
AN  - 38828776
AU  - Taylor,
AU  - D.
AU  - Albers,
AU  - B.
AU  - Mann,
AU  - G.
AU  - Lewis,
AU  - J.
AU  - Taylor,
AU  - R.
AU  - Mendes,
AU  - P.
AU  - Macdonald,
AU  - G.
AU  - Shlonsky,
AU  - A.
DB  - Juni 24.enl
DO  - /10.1177/15248380241253041
L1  - internal-pdf://0705392444/taylor-et-al-2024-systematic-review-and-meta-a.pdf
PY  - 2024
SP  - 15248380241253041
T2  - Trauma Violence &amp; Abuse
TI  - Systematic Review and Meta-Analysis of Policies and Interventions that Improve Health, Psychosocial, and Economic Outcomes for Young People Leaving the Out-of-Home Care System
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1177%2f15248380241253041
UR  - https://journals.sagepub.com/doi/10.1177/15248380241253041
ER  -
TY  - JOUR
AB  - Objective: The purpose of this study is to investigate the impact of dietary fibre on the mental health and cognitive function of children and adolescents. 

Methods: All interventional and observational studies that contained information on the relevant population (children and adolescents), intervention/exposures (high dietary fibre consumption) and outcomes (mental and cognitive parameters) were eligible. Eight electronic databases (Embase, Medline, Pubmed, Web of Science, Scopus, PsycINFO, Cochrane Library and ClinicalTrials.gov) were searched up to December 11, 2023. 

Results: A total of 15 studies (n = 4628) met inclusion criteria, consisting of 9 intervention trials and 6 observational studies. According to observational studies, higher dietary fibre consumption was associated with a 49% reduction in the odds of depression compared to lower intake (P &lt; 0.0001; OR = 0.51; 95% CI: 0.38, 0.69; I&lt;sup&gt;2&lt;/sup&gt; = 0%). Furthermore, no significant correlations were found between dietary fibre consumption and intelligence or anxiety. Among intervention studies, no significant difference was observed between fibre supplementation and placebo in terms of anxiety (standardized mean difference (SMD): -0.23; 95% CI: -0.72, 0.27), stress (SMD: 0.03; 95% CI: -0.21, 0.28), memory (SMD: 0.46; 95% CI: -0.79, 1.71), or attention (SMD: -2.72; 95% CI: -6.30, 0.86). 

Conclusion: Evidence from observation studies demonstrated that higher dietary fibre consumption is associated with a decreased odds of depression symptoms, both in childhood and adolescence. However, the causal relationship between dietary fibre intake and mental and cognitive function in children and adolescents still requires further clarification through high-quality intervention studies in the future.
AN  - 39135486
AU  - Yang,
AU  - M.
AU  - Cai,
AU  - C.
AU  - Yang,
AU  - Z.
AU  - Wang,
AU  - X.
AU  - Li,
AU  - G.
AU  - Li,
AU  - J.
AU  - Liu,
AU  - J.
AU  - Zhang,
AU  - Z.
DB  - August 2024.enl
DO  - /10.1039/d4fo02221a
L1  - internal-pdf://3548405450/Yang-2024-Effect of dietary fibre on cognitive.pdf
PY  - 2024
SP  - 8618-8628
T2  - Food &amp; Function
TI  - Effect of dietary fibre on cognitive function and mental health in children and adolescents: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.1039%2fd4fo02221a
UR  - https://pubs.rsc.org/en/content/articlelanding/2024/fo/d4fo02221a
UR  - https://pubs.rsc.org/en/content/articlepdf/2024/fo/d4fo02221a
VL  - 15
ER  -
TY  - JOUR
AB  - INTRODUCTION: Recent literature suggests that acceptance and commitment therapy (ACT) may be an effective approach for treating symptoms of depression and anxiety symptoms in adolescents. This review meta-analyzes the efficacy of ACT on adolescent depression and anxiety, emphasizing the role of process variables (i.e., psychological flexibility). 

METHODS: We systematically searched MedLine, PsycInfo and Scopus for randomized controlled trials (RCT) investigating the effect of ACT on anxiety/depression in adolescents. Studies were combined using the inverse variance method in a random effects model. Additional subgroup and meta-regression analyses were performed, and risk of bias was assessed. The review was pre-registered (PROSPERO registration number: CRD42023483300). 

RESULTS: Our review included 27 RCTs with a total of 2860 participants. ACT did not outperform CBT but was significantly more effective than other active controls (e.g., treatment as usual) for depression symptoms and inactive controls for all outcomes. ACT was more effective than inactive controls for all outcomes. Improvements in psychological flexibility significantly predicted reductions in between-group depression and anxiety. Younger age and a higher percentage of women predicted better outcomes for some outcomes. 

LIMITATIONS: It should be noted that this results may be limited by the fact that all included studies were rated as having a high risk of bias. This is mainly due to the self-reported nature of the measures and the lack of crucial methodological information (e.g., process of randomization and allocation, treatment fidelity assessment). 

CONCLUSION: Our findings support ACT&#039;s efficacy for adolescents, particularly in treating depression symptoms. The proposed mechanism of change (psychological flexibility) plays a significant role in the improvements. ACT is comparable in efficacy to CBT, suggesting its potential as an alternative to traditional cognitive-behavioral approaches.
AN  - 39303882
AU  - Lopez-Pinar,
AU  - C.
AU  - Lara-Merin,
AU  - L.
AU  - Macias,
AU  - J.
DB  - September 2024.enl
DO  - /10.1016/j.jad.2024.09.076
L1  - internal-pdf://1590318343/1-s2.0-S0165032724015660-main.cleaned.pdf
PY  - 2024
SP  - 633-644
T2  - Journal of Affective Disorders
TI  - Process of change and efficacy of acceptance and commitment therapy (ACT) for anxiety and depression symptoms in adolescents: A meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;DO=10.1016%2fj.jad.2024.09.076
VL  - 368
ER  -
TY  - JOUR
AB  - **Background**: Attention Deficit Hyperactivity Disorder (ADHD) is a common mental health condition in children that can significantly impact their quality of life. In this study, we compared the effectiveness of virtual reality (VR) technology with traditional rehabilitation training through meta-analysis, aiming to provide a basis for the clinical optimization of rehabilitation strategies.  **Methods**: The study was registered in PROSPERO, and a search was conducted using the subject terms &quot;virtual reality&quot; and &quot;attention deficit hyperactivity disorder&quot; across six databases. The search yielded 10 randomized controlled trials (RCTs) that met the inclusion criteria. The data were analyzed using a random-effects model in statistical software. **Results**: The study found that VR exercise game technology significantly outperformed the control group in terms of both the primary outcome (executive function and cognitive function) and secondary outcomes (attention, memory, and task switching) in children under the age of 18 with ADHD (children under 18 years of age are defined as adolescents and children). Sensitivity analyses confirmed the robustness of the five outcome measures. Bias tests revealed no publication bias for the primary outcome, but some bias for the secondary outcomes, which did not affect the overall results. **Conclusion**: VR motor games significantly improved the executive and cognitive functions of children with ADHD.
AN  - 39767283
AU  - Zhang,
AU  - W.
AU  - Li,
AU  - H.
AU  - Sheng,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3390/bs14121141
L1  - internal-pdf://1611113306/Zhang-2024-A Study of the Effects of Virtual R.pdf
PY  - 2024
SP  - 28
T2  - Behavioral Sciences
TI  - A Study of the Effects of Virtual Reality-Based Sports Games on Improving Executive and Cognitive Functions in Minors with ADHD-A Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.3390%2fbs14121141
UR  - https://mdpi-res.com/d_attachment/behavsci/behavsci-14-01141/article_deploy/behavsci-14-01141.pdf?version=1732788059
VL  - 14
ER  -
TY  - JOUR
AB  - **Background**
Healthy after-school activities such as participation in organised sport have been shown to serve as important resources for reducing school failure and other problem/high-risk behaviour. It remains to be established to what extent organised sport participation has positive impacts on young people in unstable life circumstances.

**Objectives**
What are the effects of organised sport on risk behaviour, personal, emotional and social skills of young people, who either have experienced or are at-risk of experiencing an adverse outcome?

**Search Methods**
The database searches were carried out in March 2023 and other sources were searched in May 2023. We searched to identify both published and unpublished literature.

**Selection Criteria**
The intervention was participation in leisure time organised sport. Young people between 6 and 18 years of age, who either have experienced or are at-risk of experiencing an adverse outcome were eligible. Primary outcomes were problem/high-risk behaviour and a secondary outcomes social and emotional outcomes. Studies that used a control group were eligible for. Studies that utilised qualitative approaches were not.

**Data Collection and Analysis**
The number of potentially relevant studies was 43,716. Thirteen studies met the inclusion criteria. Only seven studies could be used in the data synthesis. Five studies were judged to have a critical risk of bias and were excluded from the meta-analysis. One study did not report data that enabled the calculation of effect sizes and standard errors. Meta-analyses were conducted on each conceptual outcome separately. All analyses were inverse variance weighted using random effects statistical models.

**Main Results**
Two studies were from Canada, one from Australia, and the remaining from the USA. The timespan of the interventions was 23 years, from 1995 to 2018. The median number of participants analysed was 316, and the median number of controls was 452. A number of primary outcomes were reported but each in a single study only. Concerning secondary outcomes, two studies reported the effect on overall psychosocial adjustment at post-intervention. The standardised mean difference was 0.70 (95% CI 0.28&ndash;1.11). There was a small amount of heterogeneity. Three studies reported on depressive symptoms at 0&ndash;3 years follow-up. The standardised mean difference was 0.02 (95% CI &minus;0.01 to 0.06). There was no heterogeneity between the three studies. In addition, a number of other secondary outcomes were reported each in a single study only.

**Authors&#039; Conclusions**
There were too few studies included in the meta-analyses in order for us to draw any conclusion. The dominance of Northern America clearly limiting the generalisability of the findings. The majority of the studies were not considered to be of overall high quality and the process of excluding studies with critical risk of bias from the meta-analysis applied in this review left us with only 7 of a total of 13 possible studies to synthesise. Further, because too few studies reported results on the same type of outcome, at most three studies could be combined in a particular meta-analysis and no meta-analysis could be performed on any of the primary outcomes.
AU  - Filges,
AU  - T.,
AU  - Verner,
AU  - M.,
AU  - Ladekjær,
AU  - E.,
AU  - Bengtsen,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1002/cl2.1381
L1  - internal-pdf://0444736391/Filges 2024.pdf
PY  - 2024
T2  - Campbell Systematic Reviews
TI  - Participation in organised sport to improve and prevent adverse developmental trajectories of at-risk youth: A systematic review
ER  -
TY  - JOUR
AB  - Given the limited evidence, there is no conclusive proof of the neurocognitive benefits of bovine milk fat globule membrane supplementation in infant formula. This study evaluates the neurocognitive benefits of bovine milk fat globule membrane supplementation in formula, comparing it to standard formula and assessing its noninferiority to breast milk. Data were sourced from studies published between January 2000 and March 2024 from PubMed, Cochrane Library, Web of Science, and Embase. Eight randomized controlled trials involving 1352 healthy term neonates, infants, and children up to 2 years old were included. Bovine milk fat globule membrane supplementation was significantly associated with improved cognitive development (mean difference: 3.29, 95% CI: 1.65 to 4.93, p &lt; 0.001) and demonstrated minimal heterogeneity (I&lt;sup&gt;2&lt;/sup&gt; = 0%, p = 0.564). It showed significant improvement in executive function but not in language, motor, or social-emotional development. In non-inferiority analysis, there was no significant difference compared to breast milk regarding cognitive development. These findings support bovine milk fat globule membrane as a valuable addition to infant formula for cognitive benefits.
AN  - 39064816
AU  - Thongseiratch,
AU  - T.
AU  - Kittisakmontri,
AU  - K.
AU  - Chandeying,
AU  - N.
DB  - Juli 2024.enl
DO  - /10.3390/nu16142374
L1  - internal-pdf://0095567181/Thongseiratch-2024-Bovine Milk Fat Globule Mem.pdf
PY  - 2024
SP  - 22
T2  - Nutrients
TI  - Bovine Milk Fat Globule Membrane Supplementation and Neurocognitive Development: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;DO=10.3390%2fnu16142374
UR  - https://mdpi-res.com/d_attachment/nutrients/nutrients-16-02374/article_deploy/nutrients-16-02374.pdf?version=1721646997
VL  - 16
ER  -
TY  - JOUR
AB  - PURPOSE: To evaluate the effectiveness of ACT-based interventions on improving the mental health of parents of children with SHCN compared to active/inactive controls and to investigate the characteristics/components of the effective interventions in the included studies. 

METHODS: Eight databases were searched from inception to 14 February 2023. We included all randomized controlled trials (RCTs) of ACT-based interventions for parents of children with SHCN published in English or Chinese journals and dissertations reporting at least one parental mental health outcome postintervention. 

RESULTS: Fourteen RCTs were included. The results indicated significant improvements of ACT-based interventions in the stress (Hedges&#039; g = -0.36), depressive symptoms (g = -0.32), anxiety (g = -0.29), distress (g = -0.29), psychological flexibility (g = 0.51), mindful awareness/mindfulness abilities (g = 0.41), and confidence/self-efficacy (g = 0.30) of parents, as well as in the emotional and behavioural problems (EBP; g = -0.39) of their children with SHCN postintervention, with moderate to high certainty of evidence. Furthermore, the optimal components of ACT-based interventions, including the intervention approaches (ACT combined with another parenting technique/program), active participants (only involving parents), delivery mode (in-person) and format (group-based format), and desirable number of sessions (4-8 sessions), were identified to inform the design of future interventions/studies. 

CONCLUSION: This review highlights the positive effects of ACT-based interventions on mental health, psychological flexibility, mindful awareness/mindfulness abilities, and confidence/self-efficacy in parents and EBP in children with SHCN. Since group-based ACT combined with a parenting technique/program was identified as the optimal effective strategy, its effects could be further examined in larger-scale RCTs with parents and children with SHCN with diverse ethnic and sociodemographic characteristics.
AN  - 37757593
AU  - Li,
AU  - S.
AU  - Chen,
AU  - Z.
AU  - Yong,
AU  - Y.
AU  - Xie,
AU  - J.
AU  - Li,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.comppsych.2023.152426
L1  - internal-pdf://0668991751/Li_2023_III.pdf
PY  - 2023
SP  - 152426
T2  - Comprehensive Psychiatry
TI  - Effectiveness of acceptance and commitment therapy-based interventions for improving the psychological health of parents of children with special health care needs: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37757593
UR  - https://www.sciencedirect.com/science/article/pii/S0010440X23000639?via%3Dihub
VL  - 127
ER  -
TY  - JOUR
AB  - **Background** 
Feeding and eating disorders are associated with significant illness burden and costs, yet access to evidence-based care is limited. Low intensity psychological interventions have the potential to increase such access. 

**Methods** 
A systematic review and meta-analysis were conducted on the use of low intensity psychological interventions for the treatment of feeding and eating disorders. Studies comparing low intensity psychological interventions against high intensity therapies and non-eating disorder specific psychological interventions were included, as well as those with waiting list control arms. There were three primary outcomes: eating disorder psychopathology, diagnostic and statistical manual of mental disorders (DSM) severity specifier-related outcomes and rates of remission/recovery. 

**Results** 
Thirty-three studies met the inclusion criteria, comprising 3665 participants, and 30 studies were included in the meta-analysis. Compared to high intensity therapies, low intensity psychological interventions were equivalent on reducing eating disorder psychopathology (g = - 0.13), more effective at improving DSM severity specifier-related outcomes (g = - 0.15), but less likely to achieve remission/recovery (risk ratio (RR) = 0.70). Low intensity psychological interventions were superior to non-eating disorder specific psychological interventions and waiting list controls across all three primary outcomes. 

**Conclusion** 
Overall, findings suggest that low intensity psychological interventions can successfully treat eating disorder symptoms. Few potential moderators had a statistically significant effect on outcome. The number of studies for many comparisons was low and the methodological quality of the studies was poor, therefore results should be interpreted with caution. More research is needed to establish the effectiveness of low intensity psychological interventions for children and young people, as well as for individuals with anorexia nervosa, avoidant/restrictive food intake disorder, pica and rumination disorder.
AN  - WOS:000963072700002
AU  - Davey,
AU  - E.
AU  - Bennett,
AU  - S.
AU  - D.
AU  - Bryant-Waugh,
AU  - R.
AU  - Micali,
AU  - N.
AU  - Takeda,
AU  - A.
AU  - Alexandrou,
AU  - A.
AU  - Shafran,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1186/s40337-023-00775-2
L1  - internal-pdf://0718375296/Davey-2023-Low intensity psychological interve.pdf
PY  - 2023
SP  - 25
T2  - Journal of Eating Disorders
TI  - Low intensity psychological interventions for the treatment of feeding and eating disorders: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000963072700002
UR  - https://jeatdisord.biomedcentral.com/counter/pdf/10.1186/s40337-023-00775-2.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - This systematic review aimed to evaluate the effectiveness of major types of mind-body exercises (MBEs) on health-related outcomes in children and adolescents with autism spectrum disorder (ASD). 

Seven major electronic databases were systematically searched from inception to January 3, 2023. Fifteen studies consisting of ten randomized controlled trials and five controlled clinical trials with a total 651 participants aged 3-17 years were identified. 

While there was some evidence supporting the positive effects of MBE on behavioral problems in children and adolescents with ASD, there was limited evidence supporting their efficacy on other health-related outcomes such as social communication and cognitive functions. Larger and more robust trials with longer follow-up periods are needed to draw more definitive conclusions.
AN  - WOS:001088149800001
AU  - Huang,
AU  - J.
AU  - F.
AU  - Li,
AU  - X.
AU  - C.
AU  - Chen,
AU  - Z.
AU  - W.
AU  - Zou,
AU  - L.
AU  - Y.
AU  - Healy,
AU  - S.
AU  - Tse,
AU  - C.
AU  - Y.
AU  - A.
AU  - Li,
AU  - C.
AU  - X.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1007/s40489-023-00412-3
L1  - internal-pdf://2633112242/Huang-2023-Effects of Mind-Body Exercises on H.pdf
PY  - 2023
SP  - 15
T2  - Review Journal of Autism and Developmental Disorders
TI  - Effects of Mind-Body Exercises on Health-related Outcomes in Children and Adolescents with Autism Spectrum Disorder: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001088149800001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-023-00412-3.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Although emotion socialization parenting interventions are supported by a growing body of literature, their effects have yet to be systematically examined. The present systematic review and meta-analysis assesses the evidence for emotion socialization parenting interventions for parents of young children. 

METHODS: 
Six electronic databases were systematically searched from inception to October 5th, 2022. We conducted random effects meta-analyses of randomized controlled trials of emotion socialization interventions delivered to parents of children aged 18 months to 6 years 11 months. 

RESULTS: 
Twenty-six studies which reported data from 15 individual trials met the inclusion criteria. Interventions had a positive effect on positive and negative emotion socialization parenting practices (g&#039;s = 0.50) and child emotional competence (g = 0.44). Interventions also had a positive effect on positive (g = 0.74) and negative parenting behaviors (g = 0.25), parent psychological well-being (g = 0.28), and child behavioral adjustment (g = 0.34). Findings remained significant after considering potential publication bias and conducting sensitivity analyses. Two significant moderating factors emerged. 

CONCLUSIONS: 
Emotion socialization parenting interventions are effective for improving emotion socialization parenting practices and child emotional competence. Additional methodologically rigorous trials are needed to buttress the current evidence and provide evidence for additional moderating factors.
AN  - 36706555
AU  - England-Mason,
AU  - G.
AU  - Andrews,
AU  - K.
AU  - Atkinson,
AU  - L.
AU  - Gonzalez,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.cpr.2023.102252
L1  - internal-pdf://3609948988/1-s2.0-S0272735823000107-main.cleaned.pdf
PY  - 2023
SP  - 102252
T2  - Clinical Psychology Review
TI  - Emotion socialization parenting interventions targeting emotional competence in young children: A systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36706555
VL  - 100
ER  -
TY  - JOUR
AB  - In light of increasing migration rates and the unique experiences of immigrants, this meta-analysis examined the effects of parenting interventions for immigrants. Specifically, we described the characteristics of parenting interventions for immigrants, examined cultural and/or linguistic adaptations made to the interventions, analyzed intervention effects, and examined potential moderating variables. Four electronic databases were searched in February 2021 for peer-reviewed articles published in English. Studies that involved immigrant parents, used an experimental design, and investigated an intervention targeting skills that parents could use directly with their children were included. Sixteen group design and two single-case design studies met inclusion criteria. The risk of publication bias was examined using funnel plots and found to be low. Overall, most parenting interventions for immigrants focused on young children and were delivered in groups. Interventions produced small to moderate effects on parent and child outcomes, which is comparable to those for the general population. All studies made cultural adaptations, with the most common being language. Moderator analyses indicate that the effects of interventions with surface structure adaptations were similar to those with deep structure adaptations. Limitations included the low methodological rigor of included studies and the exclusion of grey literature. More works of research on the relative effects of specific adaptations, such as ethnicity matching, are needed to better serve this population. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-38767-001
AU  - Lim,
AU  - N.
AU  - O&#039;Reilly,
AU  - M.
AU  - Russell-George,
AU  - A.
AU  - Londono,
AU  - F.
AU  - V.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s11121-022-01488-9
L1  - internal-pdf://3226911709/Lim-2023-A meta-analysis of parenting interven.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Prevention Science
TI  - A meta-analysis of parenting interventions for immigrants
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc19&amp;AN=2023-38767-001
UR  - https://link.springer.com/content/pdf/10.1007/s11121-022-01488-9.pdf
ER  -
TY  - JOUR
AB  - To address the societal harms of violence, many violence prevention interventions have been developed, tested, and implemented in the general population. These have been reported in systematic reviews and meta-analyses, which have typically focused on one type of intervention or outcome. We aimed to provide a comprehensive overview of the current evidence regarding the effectiveness of different psychosocial interventions in reducing all forms of violence toward others. We have conducted an umbrella review of previous meta-analyses using standard approaches and converted findings on effectiveness into odds ratios. We tested for the underlying quality of the meta-analytic evidence by examining heterogeneity, excess statistical significance, prediction intervals, and small study effects. We identified 16 meta-analyses, including nine investigating psychosocial interventions, and five legislative and policy changes. Most meta-analyses reported positive effects of tested interventions. The strongest effects were found for sports-based initiatives, and the weakest for general population programs aimed at early childhood, youth development, and reducing sexual assault perpetration by men. Legislative changes had varying effectiveness. We conclude that simple, scalable, and cost-efficient programs, such as sport-based initiatives, have the clearest empirical support as population-based approaches to violence prevention.
AN  - 37650521
AU  - Fazel,
AU  - S.
AU  - Burghart,
AU  - M.
AU  - Wolf,
AU  - A.
AU  - Whiting,
AU  - D.
AU  - Yu,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/15248380231195880
L1  - internal-pdf://0255080250/Fazel_2023.pdf
PY  - 2023
SP  - 15248380231195880
T2  - Trauma Violence &amp; Abuse
TI  - Effectiveness of Violence Prevention Interventions: Umbrella Review of Research in the General Population
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37650521
UR  - https://journals.sagepub.com/doi/10.1177/15248380231195880
ER  -
TY  - JOUR
AB  - **Importance:** There is a gap in the evidence regarding nature-based interventions (NBIs) for children with autism spectrum disorder (ASD). 

**Objective:** To systematically review and meta-analyze available evidence on the health-related outcomes in NBIs for children with ASD. 

**Data Sources:** The Cumulative Index to Nursing and Allied Health Literature, Cochrane, Embase, Emcare, Education Resources Information Center, Global Health, MEDLINE, PsycInfo, SPORTDiscus, and Web of Science were searched from inception until May 2023. Google Scholar and references from included studies were searched for additional studies. 

**Study Selection:** Included studies were randomized clinical trials (RCTs), controlled studies, and single-group before-and-after studies that reported health-related outcomes. Data Extraction and Synthesis: This review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) reporting guidelines. Random-effects meta-analyses were used to synthesize the data. The findings of studies that were ineligible for meta-analysis were summarized according to the Synthesis Without Meta-analysis (SWIM) reporting guidelines. 

**Main Outcomes and Measures:** The outcomes of interest were health-related outcomes (ie, social functioning, behavioral functioning, emotional functioning, sensory functioning) and the self-reported well-being of children with ASD. 

**Results:** A total of 24 studies with 717 participants (mean age range, 5.3 to 17.8 years; 141 [21.9%] female) were included. A meta-analysis from 13 studies indicated a significant negative moderate association between NBIs and social communication (standardized mean difference [SMD], -0.59; 95% CI, -0.85 to -0.34). For behavioral functioning outcomes, NBIs showed a significant moderate association with reduced hyperactivity (SMD, -0.56; 95% CI, -0.86 to -0.26) and a small to moderate association with reduced irritability (SMD, -0.49; 95% CI, -0.79 to -0.19). For sensory functioning, NBIs were significantly associated with improved inattention and distractibility (SMD, 1.13; 95% CI, 0.67 to 1.60). Significant moderate associations were observed in sensory seeking (SMD, 0.77; 95% CI, 0.33 to 1.22; P &lt; .001; I2 = 0%) and sensory sensitivity (SMD, 0.56; 95% CI, 0.12 to 1.00; P = .01; I2 = 0%). Heterogeneity of the intervention effects was not high, and I2 ranged from 0% to 67%. 

**Conclusions and Relevance:** The findings of this systematic review and meta-analysis suggested an association of NBIs in group-based recreational therapy with experiential learning with positive short-term outcomes on sensory, social, and behavioral functioning for children with ASD. Future evidence using robust study design to aid the health and functional trajectories of children with ASD is recommended.
AN  - 38060224
AU  - Fan,
AU  - M.
AU  - S.
AU  - N.
AU  - Li,
AU  - W.
AU  - H.
AU  - C.
AU  - Ho,
AU  - L.
AU  - L.
AU  - K.
AU  - Phiri,
AU  - L.
AU  - Choi,
AU  - K.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1001/jamanetworkopen.2023.46715
L1  - internal-pdf://1724590115/Fan-2023-Nature-Based Interventions for Autist.pdf
PY  - 2023
SP  - e2346715
T2  - JAMA Network Open
TI  - Nature-Based Interventions for Autistic Children: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38060224
UR  - https://watermark.silverchair.com/fan_2023_oi_231361_1701362161.26468.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAy8wggMrBgkqhkiG9w0BBwagggMcMIIDGAIBADCCAxEGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM_ltjZkaFraxRmP6dAgEQgIIC4qIheiBnCZwiq4kX57BGENAped8_hFyJZB7lzN06wcRJ9DLq3hAUpNmZEqGcIQ81s_ckrpqJA4tBiIsHcUm-flgYedtM2DqejkX09Kup9YShR9OFi0pZ_QYRDGuaLjYx8sH3FF6fbpoW2UuWv1GtziBWEfgiq0yykKN8JRftBWiu-sm6ZSDQxgWoxnepF5qbLkoV3uKKDlWXY1s4CsB3AwVgc8MrUq7C6fIOktQgSERxVAPcx1DfjGdYsMR5Li3ULfHGlUZMV97zLUtK7Tt2I000s__tPNaFf3XA-l-wrS94p1LHk2FFgTGkD9S8c2uSwKDcyLQfwlFnGE0M4_jZDd4Q0OtYxZjOQDTkM8W7myEP_qh3vVpwCoxZRuqkF6CpH8jfu7x_wfRQWzbX7fgauCMBajdwN3oqdo-WKTMfIusg3Sc65781FaScs78wQzVp0Y73omZTmhTaLIqfXTOSUO8t7VHVuFZl3pQQRu9MHTqB317muJmfPUn9TwqQ0qcKdyJciWgQVA7m8Ry0wlqDRZ3mdNXb-idErQpjCywKiKpYAUrQcYQFxmCvyEozBkHdHi8Bq35KXD4xJOmwW3fCzF1mboP8hP6vewLvpdAGdtUcua8ub8xv85rLVzOL0QzzD21pEj8KkAqFPCI7ZZm96gHiRRlxfYjrqhQ5VQYNPJiPsjb7YGvn1hBum0SJbKZfI6nEMIAjuqPWfztAgoqLivvqyLvZMD9tD5RmRqddS8oyqiPJjt44ZZpz5grXWyXq80ArhDbH8XRMA8j8ErXiNCuqqYe15EZhz6YMk77N3jOcivjVErp1DUgWMfhDPblot_OKy9Erk0xODZpTjC2pEmK6t8M322iIHDXxbxlMZr2vD10jTXJg6PBrd7EgQq-cYptkX9EYY0H-0zasFNTDZGuhdS-iGjKIDRjiUp1qsNNpOQZSiyzq7A9cQXOEATN9mynP0SABJBcTpgqAHOCIql8EvA
VL  - 6
ER  -
TY  - JOUR
AB  - Anxiety symptoms and disorders are prevalent and impairing in young children and these symptoms often persist and worsen over time, indicating the need for efficacious interventions for this age group. The purpose of this study was to evaluate the effectiveness of psychosocial interventions targeting anxiety in younger children and to assess the potential moderators of outcome. The effect sizes from 24 trials were assessed based on a random effect model. The mean weighted effect size was found to be significant and moderate in magnitude. Moderators, including level of intervention, intervention approach, rater, and level of training of the provider/program facilitator, are assessed and discussed. Overall, the findings indicate that anxiety interventions are effective in reducing anxiety in young children, and targeted trials show particularly strong promise.
AN  - WOS:000993312700001
AU  - Fisak,
AU  - B.
AU  - Penna,
AU  - A.
AU  - Mian,
AU  - N.
AU  - D.
AU  - Lamoli,
AU  - L.
AU  - Margaris,
AU  - A.
AU  - Dela
AU  - Cruz,
AU  - Samf
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1007/s10826-023-02596-y
L1  - internal-pdf://2291061012/Fisak-2023-The Effectiveness of Anxiety Interv.pdf
PY  - 2023
SP  - 12
T2  - Journal of Child and Family Studies
TI  - The Effectiveness of Anxiety Interventions for Young Children: A Meta-Analytic Review
UR  - &lt;Go to ISI&gt;://WOS:000993312700001
UR  - https://link.springer.com/content/pdf/10.1007/s10826-023-02596-y.pdf
ER  -
TY  - JOUR
AB  - **Objective:**
This study aims to perform a systematic review and meta-analysis of the effect of MBIs (Mindfulness, Tai Chi, Yoga, and Qigong) on symptoms and executive function (EF) in ADHD. 

**Method:** 
PubMed, Web of Science, the Cochrane Library, PsycINFO, CINAHL, Embase, and CNKI databases were searched to collect randomized controlled trials (RCTs) on the effects of MBIs on symptoms and EF in ADHD. Data extraction and methodological quality evaluation were conducted by two researchers, and a meta-analysis was conducted by Stata SE. 

**Results:** 
The pooled meta-analyses of MBIs revealed a positive and small effect on inattention (g = -0.26), hyperactivity/impulsivity (g = -0.19), and EF (g = -0.35). 

**Conclusion:** 
Results suggest that MBIs have a significant improvement relative to the control condition. Although some results show that symptoms are affected by age, interventions, and total time of moderators, while EF is not affected by age and measurement, it needs to be supported by more research evidence. (J. of Att. Dis. XXXX; XX(X) XX-XX)
AN  - WOS:000935340800001
AU  - Zhang,
AU  - Z.
AU  - P.
AU  - Chang,
AU  - X.
AU  - L.
AU  - Zhang,
AU  - W.
AU  - J.
AU  - Yang,
AU  - S.
AU  - Y.
AU  - Zhao,
AU  - G.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/10870547231154897
L1  - internal-pdf://0581954535/Zhang Z.pdf
PY  - 2023
SP  - 15
T2  - Journal of Attention Disorders
TI  - The Effect of Meditation-Based Mind-Body Interventions on Symptoms and Executive Function in People With ADHD: A Meta-Analysis of Randomized Controlled Trials
UR  - &lt;Go to ISI&gt;://WOS:000935340800001
ER  -
TY  - JOUR
AB  - **Purpose:** Adolescents are particularly vulnerable to suicide attempts, which is a major risk factor for completed suicide in this age group. However, most research on suicide prevention interventions comes from high-income countries with predominantly white participants and English protocols. This study examines interventions that have been tested in Latin America and Spain. 

**Methods:** A systematic review was conducted to include interventions aimed at reducing suicide ideation, attempts, and increasing knowledge about it in these regions. 

**Results:** Sixteen articles were selected, and Dialectical Behaviour Therapy, Problem Solving Therapy, and Trauma-Focused Cognitive Behavioural Therapy were found to be more effective than standard treatments or wait-list conditions in reducing the outcomes. 

**Discussion:** This review highlights the need for more research on preventive interventions in Latin America and Spain. While all interventions evaluated were effective, further research and replication studies are necessary to strengthen the evidence base for these interventions.
AN  - WOS:001078094600001
AU  - Ca&ntilde;izares,
AU  - C.
AU  - Macgowan,
AU  - M.
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1177/10497315231178462
L1  - internal-pdf://1121980591/canizares-j-macgowan-2023-interventions-for-ad.pdf
PY  - 2023
SP  - 21
T2  - Research on Social Work Practice
TI  - Interventions for Adolescent Suicide Ideation and Suicide Attempts in Latin America and Spain: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001078094600001
ER  -
TY  - JOUR
AB  - BAKGRUNN:
VIP Makkerskap er et helsefremmende og universalforebyggende tiltak, som er utviklet for å sikre en bedre overgang fra ungdomsskolen til Vg1, og fra barne- til ungdomsskolen, for en bedre skolestart og for å fremme et godt læringsmiljø. VIP Makkerskap er utviklet og eiet av Vestre Viken HF/VIP psykisk helse i skolen, med finansiering fra Helsedirektoratet over tilskuddsordningen &laquo;Psykisk helse i skolen&raquo;.

METODE:
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

RESULTATER:
Resultatene består av en vurdering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. VIP Makkerskap vurderes som godt beskrevet med et bredt faglig fundament, men det har en noe uklar teoretisk referanseramme. Tiltaket tilbyr noe implementeringsstøtte i form av informasjonsmøter og tilbud om 3-timers opplæring, men ingen prosedyrer for å sikre eller måle implementeringens kvalitet. Det er gjennomført en norsk effektstudie, presentert i to artikler, der kvasieksperimentelt design benyttes. Funnene indikerer en signifikant bedring for skoler med VIP Makkerskap på ett utfallsmål, sosialt klassemiljø, sammenlignet med kontrollskoler som ikke gjennomførte programmet. Effekten var liten, og fordi VIP Makkerskap ved noen skoler ble innført før baseline og avhengighet (nesting) i data ikke ble tatt hensyn til i analysene, er funnene noe usikre. Det ble også funnet korttidseffekter for lykke og depresjon-/angstsymptomer for elever uten eller med lav sosial angst ved baseline, men ingen effekter for elever med høy sosial angst, og det ble ikke funnet signifikante effekter etter 6 måneder. Når det gjelder ensomhet var det ingen kort- eller langtidseffekter.Det er behov for flere effektstudier av høy kvalitet som kan gi mer valide effektestimater på relevante utfallsmål både på videregående skole og i ungdomsskolen. I tillegg bør det teoretiske rasjonale for tiltaket bli tydeligere og mer spisset, og begrunnes ut fra primærlitteratur og implementeringsstrategien bør videreutvikles.

KONKLUSJON:
VIP Makkerskap klassifiseres på evidensnivå 3 &ndash; tiltak med noe dokumentasjon på effekt.
AU  - Havik,
AU  - T.
AU  - Rye,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /post_tiltak_arkiv/vip-makkerskap-1-utg/
L1  - internal-pdf://3674544172/VIP-Makkerskap.cleaned.pdf
PY  - 2023
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: VIP-Makkerskap (1. utg.)
ER  -
TY  - JOUR
AB  - Students with emotional-behavioral disorders (EBDs) often learn in alternative classroom settings to provide more intensive instruction that meets their educational needs. Although research has demonstrated promise for several behavior intervention practices in general education settings, the generalizability of these practices to more restricted environments is unknown. Thus, this meta-analysis aimed to examine the class-wide behavior interventions tested in self-contained learning environments for students with EBDs. Studies investigating behavioral interventions in alternative elementary settings were systematically screened. Fifteen studies with 20 effect sizes met inclusion criteria and results from each study were synthesized. An estimated average effect was calculated (g = 0.93, SE = 0.16), demonstrating that tested interventions are typically effective in self-contained learning environments to improve student behaviors. A thematic analysis and multi-level meta-regression were conducted to determine which elements are most beneficial to students in these unique learning environments. Results indicated that interventions that included relational supports, such as daily parent communication, differentially benefited students (B = 1.26, SE = 0.15). Limitations include the small number of studies meeting inclusion criteria that have investigated behavior interventions in self-contained settings and the need for improved research quality. Implications suggest support for adapting standardized practice elements, such as group contingencies, to improve student behaviors in multiple learning environments.
AN  - WOS:000954235500001
AU  - Gersib,
AU  - J.
AU  - A.
AU  - Mason,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/01987429231160285
L1  - internal-pdf://1019089832/Gersib_2023.pdf
PY  - 2023
SP  - 15
T2  - Behavioral Disorders
TI  - A Meta-Analysis of Behavior Interventions for Students With Emotional-Behavioral Disorders in Self-Contained Settings
UR  - &lt;Go to ISI&gt;://WOS:000954235500001
UR  - https://journals.sagepub.com/doi/10.1177/01987429231160285
ER  -
TY  - JOUR
AB  - **Objective:** 
The development of serious games for mental wellbeing is a topic of growing interest. The increase in acceptance of games as a mainstream entertainment medium combined with the immersive qualities of games provides opportunities for meaningful support and intervention in mental wellbeing.

**Method:** 
We conducted a systematic review and exploratory meta-analysis to examine if aspects of the interventions influenced outcomes as measured via overall effect sizes. We employed a multilevel meta-analytic approach to accommodate the interdependency of effect sizes (18 effect sizes from 14 studies, with 2027 participants).

**Results:** 
Overall, the main effect for gaming interventions on any outcome variable was small to medium sized, d = .35 (confidence interval [.23, 47], p &lt; .001). Results revealed that the only significant moderator was the nature of the intervention. Specifically, only interventions that included a rational emotional behavioural focus significantly predicted an improvement in depression and/or anxiety in participants.

**Conclusion:** 
The findings reveal promising effects for therapeutic games for mental health, but replications are needed, alongside the addressing of methodological and procedural concerns.
AN  - WOS:001110242100001
AU  - Eve,
AU  - Z.
AU  - Turner,
AU  - M.
AU  - Di
AU  - Basilio,
AU  - D.
AU  - Harkin,
AU  - B.
AU  - Yates,
AU  - A.
AU  - Persson,
AU  - S.
AU  - Henry,
AU  - J.
AU  - Williams,
AU  - A.
AU  - Walton,
AU  - G.
AU  - Jones,
AU  - M.
AU  - V.
AU  - Whitley,
AU  - C.
AU  - Craddock,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/cpp.2938
L1  - internal-pdf://3328800645/Eve-2023-Therapeutic games to reduce anxiety a.pdf
PY  - 2023
SP  - 14
T2  - Clinical Psychology &amp; Psychotherapy
TI  - Therapeutic games to reduce anxiety and depression in young people: A systematic review and exploratory meta-analysis of their use and effectiveness
UR  - &lt;Go to ISI&gt;://WOS:001110242100001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpp.2938?download=true
ER  -
TY  - JOUR
AB  - **Objective:** 
Evidence-based research methods were applied to assess the efficacy of faecal microbiota transplantation (FMT) for the treatment of autism in children. 

**Methods:** 
We searched the Chinese Biomedical Literature, CNKI, Wanfang, PubMed, Embase, Web of Science, and the Cochrane Library databases to collect randomised controlled trials on faecal microbiota transplantation for the treatment of autism in children. The search included studies published from the creation of the respective database to 5 April 2022. Literature screening, data extraction, and quality evaluation were implemented by three investigators according to the inclusion and exclusion criteria. The meta-analysis was performed using the RevMan 5.1 software. 

**Results:** 
Nine studies with population-based subjects and four studies with animal-based subjects were included. Five papers were screened for the meta-analysis. The results showed that FMT markedly reduced Autism Behaviour Checklist (ABC) scores in children with autism spectrum disorder (weighted mean difference (WMD) = -14.96; 95% confidence intervals (CI), -21.68 to -8.24; P &lt; 0.001; I &lt;sup&gt;2&lt;/sup&gt; = 0%). FMT also reduced Childhood Autism Rating Scale (CARS) scores (WMD = -6.95; 95% CI, -8.76 to -5.14; P &lt; 0.001; I &lt;sup&gt;2&lt;/sup&gt; = 28.1%). 

**Conclusion:** 
Our results indicate that FMT can benefit children with autism by reducing ABC and CARS scores, but more high-quality studies are needed to verify these results.
AN  - 36818228
AU  - Zhu,
AU  - D.
AU  - Jin,
AU  - X.
AU  - Guo,
AU  - P.
AU  - Sun,
AU  - Y.
AU  - Zhou,
AU  - L.
AU  - Qing,
AU  - Y.
AU  - Shen,
AU  - W.
AU  - Ji,
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1155/2023/5993628
L1  - internal-pdf://3572897455/Zhu-2023-Efficacy of Faecal Microbiota Transpl.pdf
PY  - 2023
SP  - 5993628
T2  - Evidence-Based Complementary &amp; Alternative Medicine: eCAM
TI  - Efficacy of Faecal Microbiota Transplantation for the Treatment of Autism in Children: Meta-Analysis of Randomised Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36818228
UR  - https://downloads.hindawi.com/journals/ecam/2023/5993628.pdf
VL  - 2023
ER  -
TY  - JOUR
AB  - OBJECTIVES: 
This systematic review and meta-analysis synthesized the evidence from randomized controlled trials comparing vitamin D and placebo in reducing depressive symptoms and contributing to all-cause dropout rates. 

METHODS: 
Inclusion criteria were randomized controlled trials comparing reduced depression between depressed patients receiving vitamin D and those receiving placebo. We searched PubMed, Embase, Web of Science, and the Cochrane Central Register of Controlled Trials through January 2022. 

RESULTS: 
Eighteen trials (1980 participants, median age 39 y) were included in the meta-analysis. Vitamin D supplements were significantly superior to placebo in reducing depression (standardized mean difference = -0.49; 95% confidence interval [CI], -0.75 to -0.23; I&lt;sup&gt;2&lt;/sup&gt; = 81%). Depressed adults (standardized mean difference = -0.70; 95% CI, -1.09 to -0.31) responded to vitamin D significantly better than children and adolescents (standardized mean difference = 0.10; 95% CI -0.27 to 0.47). Vitamin D administered as bolus doses (oral intermittent high doses or intramuscular single high dose) appeared to be more effective than that taken daily by the oral route (P &lt; 0.01). Patients with more severe depression tended to respond better than those with less severity (P = 0.053). We found no moderating effect of concurrent antidepressant use, presence of major depressive disorder diagnosis, physical comorbidity, sex, duration and doses of vitamin D supplement, serum 25-hydroxyvitamin D levels at baseline, and changes in serum 25-hydroxyvitamin D levels in the vitamin D group. Dropout rates were indifferent between the groups (17 trials; risk ratio = 0.84; 95% CI, 0.6-1.16; I&lt;sup&gt;2&lt;/sup&gt; = 0). 

CONCLUSIONS: 
Heterogeneous data suggested that vitamin D supplements are effective and safe for depressed patients.
AN  - 36716601
AU  - Srifuengfung,
AU  - M.
AU  - Srifuengfung,
AU  - S.
AU  - Pummangura,
AU  - C.
AU  - Pattanaseri,
AU  - K.
AU  - Oon-Arom,
AU  - A.
AU  - Srisurapanont,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.nut.2022.111968
L1  - internal-pdf://3213813478/1-s2.0-S089990072200380X-main.cleaned.pdf
PY  - 2023
SP  - 111968
T2  - Nutrition
TI  - Efficacy and acceptability of vitamin D supplements for depressed patients: A systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36716601
VL  - 108
ER  -
TY  - JOUR
AB  - Negative cognitions play a key role in the development and maintenance of depression. To reduce depressive symptoms, most interventions either encourage adolescents to change negative cognitions, theorizing that the presence of negative cognitions underlies depression, or to acknowledge negative cognitions, theorizing that one&#039;s reaction to negative cognitions underlies depression. We compared these two therapeutic strategies in a multilevel meta-analysis of the effects of changing versus acknowledging cognitions on adolescent depression. We searched three databases in June 2022 and identified 104 randomized controlled trials (335 effect sizes). The sample comprised 27,978 adolescents (sample mean age 14-18 years) with all levels of depressive symptoms (M-age = 15.6 years; 63% female; 65% ethnic majority). The overall effect of interventions on depression was small (d = 0.21, p &lt; .001). We found no evidence that either strategy was superior to the other. Strategies to acknowledge (d = 0.23, p = .016) or change cognitions (d = 0.20, p &lt; .001) both reduced adolescent depression. Our findings suggest, though based on self-reported outcomes, that both strategies are effective in reducing adolescent depression, which allows for flexibility for clinicians and patients. The next step to further understand these strategies is to scrutinize the relative effects of single versus combined approaches to change and acknowledge negative cognitions.
AN  - WOS:000940126700001
AU  - Ulukoylu,
AU  - S.
AU  - Leijten,
AU  - P.
AU  - Assink,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/10634266231154209
L1  - internal-pdf://4273853231/Ulukoylu.pdf
PY  - 2023
SP  - 12
T2  - Journal of Emotional and Behavioral Disorders
TI  - Changing or Acknowledging Cognitions: A Meta-Analysis of Reducing Depression in Adolescence
UR  - &lt;Go to ISI&gt;://WOS:000940126700001
ER  -
TY  - JOUR
AB  - **Background** 
The incidence of depression, anxiety, and post-traumatic stress disorder (PTSD) among children and adolescents residing in low- and middle-income countries (LMICs) poses a significant public health concern. However, there is variation in the evidence of effective psychological interventions. This meta-analysis aims to provide a complete overview of the current body of evidence in this rapidly evolving field. 

**Methods** 
We conducted searches on PubMed, Embase.com, and EBSCO/APA PsycInfo databases up to June 23, 2022, identify randomized controlled trials (RCTs) investigating the effectiveness of psychological interventions in LMICs that targeted children and adolescents with elevated symptoms above a cut-off score for depression, anxiety, and PTSD, comparing a psychological or psychosocial intervention with other control conditions. We conducted random effects meta-analyses for depression, anxiety, and PTSD symptoms. Sensitivity analysis for outliers and high-risk studies, and analyses for the publication bias were carried out. Subgroup analyses investigated how the intervention type, intervention format, the facilitator, study design, and age group of the participant predicted effect sizes. 

**Results** 
Thirty-one RCTs (6,123 participants) were included. We found a moderate effect of interventions on depression outcomes compared to the control conditions (g = 0.53; 95% CI: 0.06-0.99; NNT = 6.09) with a broad prediction interval (PI) (-1.8 to 2.86). We found a moderate to large effect for interventions on anxiety outcomes (g = 0.88; 95% CI: -0.03 to 1.79; NNT = 3.32) with a broad PI (-3.14 to 4.9). Additionally, a moderate effect was observed on PTSD outcomes (g = 0.54; 95% CI: 0.19-0.9; NNT = 5.86) with a broad PI (-0.64 to 1.72). 

**Conclusions** 
Psychological and psychosocial interventions aimed at addressing depression, anxiety, and PTSD among children and adolescents in LMICs have demonstrated promising results. However, future studies should consider the variation in evidence and incorporate long-term outcomes to better understand the effectiveness of these interventions. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AD  - Alozkan-Sever, Cansu: c.alozkan@vu.nlAlozkan-Sever, Cansu: Department of Clinical, Neuro- and Developmental Psychology, WHO Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, NetherlandsUppendahl, Jana R.: Chair of Social Pediatrics, TUM School of Medicine, Technical University of Munich, Munich, GermanyCuijpers, Pim: Department of Clinical, Neuro- and Developmental Psychology, WHO Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlandsde Vries, Ralph: Medical Library, Vrije Universiteit Amsterdam, Amsterdam, NetherlandsRahman, Atif: Department of Primary Care and Mental Health, Institute of Population Health, University of Liverpool, Liverpool, United KingdomMittendorfer-Rutz, Ellenor: Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, SwedenAkhtar, Aemal: Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, SwedenZheng, Zhuoli: Faculty of Psychology and Educational Sciences, KU Leuven, Leuven, BelgiumSijbrandij, Marit: Department of Clinical, Neuro- and Developmental Psychology, WHO Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
AN  - 2024-15263-001
AU  - Alozkan-Sever,
AU  - C.
AU  - Uppendahl,
AU  - J.
AU  - R.
AU  - Cuijpers,
AU  - P.
AU  - de
AU  - Vries,
AU  - R.
AU  - Rahman,
AU  - A.
AU  - Mittendorfer-Rutz,
AU  - E.
AU  - Akhtar,
AU  - A.
AU  - Zheng,
AU  - Z.
AU  - Sijbrandij,
AU  - M.
DA  - Oct
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13891
DP  - Ovid Technologies
KW  - Children
KW  - adolescents
KW  - depression
KW  - anxiety
KW  - post-traumatic stress disorder (PTSD)
KW  - low- and middle-income countries (LMICs)
KW  - psychological interventions
KW  - meta-analysis
KW  - *Anxiety Disorders
KW  - *Major Depression
KW  - *Posttraumatic Stress Disorder
KW  - *Psychosocial Interventions
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
L1  - internal-pdf://0562122650/Alozkan-Sever-2023-Research review_ Psychologi.pdf
M3  - Literature Review
Systematic Review
Meta Analysis
N1  - PS - First Posting
PY  - 2023
SP  - No Pagination Specified
T2  - Journal of Child Psychology and Psychiatry
TI  - Research review: Psychological and psychosocial interventions for children and adolescents with depression, anxiety, and post-traumatic stress disorder in low- and middle-income countries - a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2024-15263-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1111%2Fjcpp.13891&amp;issn=0021-9630&amp;isbn=&amp;volume=&amp;issue=&amp;spage=No&amp;pages=No+Pagination+Specified&amp;date=2023&amp;title=Journal+of+Child+Psychology+and+Psychiatry&amp;atitle=Research+review%3A+Psychological+and+psychosocial+interventions+for+children+and+adolescents+with+depression%2C+anxiety%2C+and+post-traumatic+stress+disorder+in+low-+and+middle-income+countries+-+a+systematic+review+and+meta-analysis.&amp;aulast=Alozkan-Sever&amp;pid=%3Cauthor%3EAlozkan-Sever%2C+Cansu%3C%2Fauthor%3E%3CAN%3E2024-15263-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.13891?download=true
ER  -
TY  - JOUR
AB  - Children and adolescents who experience the loss of a beloved one in traumatic circumstances can experience prolonged grief symptoms, characterized by symptomatology that may alter the grieving process, impair global functioning, and interact with cognitive development. Cognitive behavioral therapy (CBT) has been showing significant results in treating grief-related issues. The present systematic review assessed the effectiveness of CBT for prolonged grief symptoms in the pediatric population. This study was carried out by two independent reviewers who searched electronic databases through a combination of keywords and a set of inclusion and exclusion criteria. A total of 20 studies were selected and data were synthesized in these categories: characteristics of the participants; specificities of the instruments; effectiveness of CBT. The results of this systematic review highlighted significant improvements in prolonged grief symptoms and global functioning following CBT. No significant age, gender, or ethnicity differences were found in most studies. The Inventory of Prolonged Grief for Children/Adolescents and the Inventory of Complicated Grief-Revised for Children appear to be the pediatric population&#039;s most sensitive prolonged grief measures. The treatments were adapted based on various contextual and structural factors without losing clinical significance. Significant effect sizes were found for primary and most secondary outcomes. This systematic review underlines the effectiveness of CBT for prolonged symptoms in the pediatric population. Nonetheless, the included studies had a certain degree of heterogeneity, and their quality varied due to some biases. A validation procedure of standard methodologies for prolonged grief symptoms in children and adolescents is required to establish shared directions both in research and clinical settings. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-99571-001
AU  - Saladino,
AU  - V.,
AU  - Verrastro,
AU  - V.,
AU  - Calaresi,
AU  - D.,
AU  - Barberis,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/str0000301
L1  - internal-pdf://0589998475/Saladino_2023.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - International Journal of Stress Management
TI  - The effectiveness of cognitive behavioral therapy for prolonged grief symptoms in children and adolescents: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-99571-001
ER  -
TY  - JOUR
AB  - Sleep initiation and maintenance problems are common in the pediatric population and while behavioral interventions are recommended, their efficacy remains to be evaluated in clinical trials. 

We conducted a systematic review and network meta-analysis to assess the efficacy of non-pharmacological treatments and melatonin for sleep initiation and maintenance problems in healthy pediatric populations. We included 30 studies in the systematic review and 15 in the meta-analysis. Three network meta-analyses were conducted for sleep onset latency (SOL), wake after sleep onset (WASO), and total sleep time (TST). 

For SOL variable, the results support greater effectiveness of light therapy and melatonin than evidence-based psychological interventions, whether implemented in combination with light therapy or not. Regarding WASO variable, evidence-based psychological interventions and a combination of those techniques plus light treatment were the most efficacious. Finally, for TST variable, a larger effect was shown for the combined treatment of evidence-based psychological intervention with light therapy in comparison to other interventions. 

In conclusion, we found a high variability between study protocols likely impacting the results of the meta-analysis. Future randomized control trials studies, stratified by pediatric age classes, are needed in order to provide clear suggestions in clinical settings.
AN  - 37406497
AU  - Mombelli,
AU  - S.
AU  - Bacaro,
AU  - V.
AU  - Curati,
AU  - S.
AU  - Berra,
AU  - F.
AU  - Sforza,
AU  - M.
AU  - Castronovo,
AU  - V.
AU  - Ferini-Strambi,
AU  - L.
AU  - Galbiati,
AU  - A.
AU  - Baglioni,
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.smrv.2023.101806
L1  - internal-pdf://0804529282/Mombelli_2023.pdf
PY  - 2023
SP  - 101806
T2  - Sleep Medicine Reviews
TI  - Non-pharmacological and melatonin interventions for pediatric sleep initiation and maintenance problems: A systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37406497
UR  - https://www.sciencedirect.com/science/article/pii/S108707922300062X?via%3Dihub
VL  - 70
ER  -
TY  - JOUR
AB  - To explore the effect of exercise intervention on fundamental movement skills (FMS) of children with attention deficit hyperactivity disorder (ADHD) and/or autism spectrum disorder (ASD). Following the principle of PICOS, randomized controlled trials of the effect of exercise intervention on the FMS of ADHD/ASD children were searched. A total of 12 articles and 396 participants were included. Review Manager5.4 and Stata16.0 software were used to process and analyze the data. The results revealed that (1) exercise intervention can improve the gross motor skills of children with ADHD/ASD (p &lt; 0.00001). Aquatic therapy (SMD = 56.54, 95% CI = 38.83-74.25) has a better effect on stability skills, and FMS intervention (SMD = 17.58, 95% CI = 1.78-33.38) has a better effect on locomotor skills and object control skills. (2) Exercise intervention can improve the fine motor skills of children with ADHD/ASD (p = 0.001). Table tennis exercise (SMD = 9.91, 95% CI = 0.23-19.59) and horse-riding program (SMD = 9.50, 95% CI = 5.20-13.80) have better effects on fine manual control and hand-eye coordination. (3) The closed-skill intervention for 60 min each time, twice a week, for at least 12 weeks had the best effect on the improvement in the FMS in children with ADHD/ASD (p &lt; 0.00001). Exercise intervention may effectively improve FMS in children with ADHD/ASD. Intervention form, time, frequency, and duration are important moderator variables that positively impact the FMS of children with ADHD/ASD.
AN  - WOS:000958481100001
AU  - Ye,
AU  - Y.
AU  - Ning,
AU  - K.
AU  - Wan,
AU  - B.
AU  - J.
AU  - Shangguan,
AU  - C.
AU  - Z.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3390/su15065206
L1  - internal-pdf://3017831854/Ye-2023-The Effects of the Exercise Interventi.pdf
PY  - 2023
SP  - 13
T2  - Sustainability
TI  - The Effects of the Exercise Intervention on Fundamental Movement Skills in Children with Attention Deficit Hyperactivity Disorder and/or Autism Spectrum Disorder: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000958481100001
UR  - https://mdpi-res.com/d_attachment/sustainability/sustainability-15-05206/article_deploy/sustainability-15-05206.pdf?version=1678874526
VL  - 15
ER  -
TY  - JOUR
AB  - This systematic review evaluated the treatment effects of communication-focused parent-mediated interventions (CF-PMT), a form of intervention that involves therapists observing parent-child interactions and giving feedback to parents on how they can practice positive parenting strategies to prevent or reduce externalizing behaviours in children with developmental disabilities. A literature search was conducted on three electronic databases. To be included in the review, studies had to: evaluate CF-PMT where therapists give feedback after observing parent-child interactions; examine changes in externalizing behaviours amongst children with any forms of developmental disability; and adopt a randomised controlled trial study design. Fifteen studies met eligible criteria for the literature review, of those, 13 studies had available data on changes in the primary (child externalizing behaviours) and secondary outcomes (parental stress, child linguistic abilities and child social responsiveness). We found significant treatment effects for CF-PMT in reducing child externalizing behaviours (d = -.60) but not for any of the secondary outcomes. A sensitivity analysis showed a small but significant treatment effect for parental stress (d = -.18). Considerable bias was observed due to the lack of available information reported by studies on aspects measured by the Mixed Methods Appraisal Tool. Overall, we found evidence to support the benefits of complex interventions which incorporate direct parent-child observations and feedback to improve behavioural outcomes amongst children with developmental disabilities.
AN  - 37748447
AU  - Kei,
AU  - N.
AU  - Hassiotis,
AU  - A.
AU  - Royston,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/13591045231203097
L1  - internal-pdf://2863791469/Kei_2023.pdf
PY  - 2023
SP  - 13591045231203097
T2  - Clinical Child Psychology &amp; Psychiatry
TI  - The effectiveness of parent-Child observation in parent-Mediated programmes for children with developmental disabilities and externalizing disorders: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37748447
UR  - https://journals.sagepub.com/doi/10.1177/13591045231203097
ER  -
TY  - JOUR
AB  - Excessive aggression in children and youth can lead to impairments in family, social or academic functioning. The aim of the present study was to review the evidence on the effectiveness of nutritional supplements in reducing excessive hetero-aggression in children and youth (up to 18 years). The Cochrane Library, EMBASE, MEDLINE, ProQuest Dissertations &amp; Theses, PsycINFO, and PubMed data bases were searched for relevant studies. Altogether, 22 studies met inclusion criteria; 13 investigated the effect of macronutrients (fatty acids and amino acids), 6 studies investigated the effect of micronutrients (vitamins and minerals), while 3 studies investigated a combination of macro-and micronutrients. Out of the 22 studies, 7 reported a beneficial effect of nutritional supplementation (vitamins and minerals, essential fatty acids, or a certain combination of these); eight studies did not report a significant beneficial effect of nutritional supplementation (essential fatty acids, vitamin D, and L-tryptophan); while 7 studies reported mixed effects (vitamin B6, essential fatty acids alone and in combination with vitamins and minerals, and carnitine). The results overall suggest that there may be a role for broad-range vitamin and mineral supplements in the treatment of hetero-aggression in youth and children, while the evidence for single-nutrient supplements is quite ambiguous.
AN  - WOS:000982449900001
AU  - Qamar,
AU  - R.
AU  - Wang,
AU  - S.
AU  - M.
AU  - Qureshi,
AU  - F.
AU  - M.
AU  - LaChance,
AU  - L.
AU  - Kolla,
AU  - N.
AU  - J.
AU  - Thege,
AU  - B.
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1016/j.avb.2023.101841
L1  - internal-pdf://1201004599/1-s2.0-S1359178923000289-main.cleaned.pdf
N1  - Brynhildur Axelsdottir (2023-07-04 18:26:16)(Select): Litt varierende grad av rapportering av resultater - inkluderer for å se på det sammen;
PY  - 2023
SP  - 12
T2  - Aggression and Violent Behavior
TI  - Nutritional supplementation in the management of childhood/youth aggression: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000982449900001
VL  - 71
ER  -
TY  - JOUR
AB  - Although some studies showed the beneficial effects of physical activity interventions on aggression among children and adolescents, the current literature is inconclusive regarding various physical activity interventions and aggression subtypes. Therefore, we conducted a systematic review and meta-analysis to examine the effects of physical activity on total aggression and its subtypes, considering the differing effects on different age groups and gender. Fifteen studies were included, involving 2003 participants in this review. The meta-analysis revealed a modest pooled effect of physical activity on aggression with others-reported measures (Hedges&#039; g = -0.28), and medium-to-large effect sizes of physical activity intervention on total aggression score (g = -0.49) and hostility (g = -0.83) among participants with aggressive tendency. However, the effects of physical activity on aggression and its subscales with self-reported measures, and the differences between subgroups (such as ages, gender, intervention types) were non-significant. These findings indicate that physical activity can be effective in reducing aggression as reported by others, especially regarding anger and hostility subscales, and among participants with aggressive tendency. High quality intervention trails are necessary to achieve more detailed understanding of physical activity reducing aggression among children and adolescents. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-55727-001
AU  - Ouyang,
AU  - N.
AU  - Liu,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.avb.2023.101821
L1  - internal-pdf://2125084165/Ouyang_2023.pdf
PY  - 2023
SP  - 1-13
T2  - Aggression and Violent Behavior
TI  - Effect of physical activity interventions on aggressive behaviors for children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-55727-001
UR  - https://www.sciencedirect.com/science/article/pii/S1359178923000083?via%3Dihub
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** 
This systematic review examined the effectiveness of Emergency Department-based and initiated youth suicide prevention interventions for suicide attempts, suicidal ideation, hospitalization, family system functioning, and other mental health symptoms. 

**METHODS:** 
We searched five databases for randomized controlled trial (RCT) studies that examined Emergency Department-based and initiated suicide prevention interventions among youth aged 10 to 18 years old between May 2020 to June 2022. Using Cohen&#039;s d and 95% confidence interval as our standardised metrics, we followed the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) and Synthesis Without Meta-Analysis in Systematic Reviews (SWiM) guidelines when synthesizing, interpreting, and reporting the findings of this review. 

**RESULTS:** 
Five studies were included in this review. Findings were first synthesized according to the targeted population of the study intervention and this review&#039;s outcomes. Two interventions were effective for decreasing depressive symptoms, hospitalization recidivism, and/or increasing family empowerment. There were no interventions that reduced subsequent suicide attempts. A meta-analysis was not conducted due to the heterogeneity of the data. 

**CONCLUSION:** 
A need exists to develop and evaluate Emergency Department-based and initiated youth suicide prevention interventions that can be successfully and sustainably implemented in practice. Future research should focus on evaluating the components of interventions that effectively mitigate suicide risk among high-risk youth.
AN  - 38051744
AU  - Balasa,
AU  - R.
AU  - Lightfoot,
AU  - S.
AU  - Cleverley,
AU  - K.
AU  - Stremler,
AU  - R.
AU  - Szatmari,
AU  - P.
AU  - Alidina,
AU  - Z.
AU  - Korczak,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0289035
L1  - internal-pdf://0018227533/Balasa-2023-Effectiveness of emergency departm.pdf
PY  - 2023
SP  - e0289035
T2  - PLoS ONE [Electronic Resource]
TI  - Effectiveness of emergency department-based and initiated youth suicide prevention interventions: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38051744
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0289035&amp;type=printable
VL  - 18
ER  -
TY  - JOUR
AB  - AIM: To systematically review the effectiveness of caregiver and parent skills training programs, including caregiver-mediated interventions, for caregivers of individuals with neurodevelopmental disorders.

METHOD: We conducted a systematic review with a random-effects meta-analysis. We searched 11 electronic databases through July 2021 and used a snowball methodology to locate relevant articles of randomized controlled trials. Effect size estimates were pooled using Hedges&#039; g from data extracted from study reports and through author requests using random-effects meta-analyses for three child outcome categories (child development, adaptive behavior, and problem behavior) and three caregiver outcome categories (parenting skills and knowledge, psychological well-being, and interpersonal family relations).

RESULTS: We located 44 910 records, from which 75 randomized controlled trials involving 4746 individuals with neurodevelopmental disorders and their caregivers were included. Random-effects meta-analyses showed improvements in child development (g = 0.30; 99% confidence interval [CI] = 0.07-0.53) and reduction in reported problem behaviors (g = 0.41; 99% CI = 0.24-0.59), but not a statistically significant improvement in adaptive behavior (g = 0.28; 99% CI = -0.42 to 0.98). Caregivers showed improvements in parenting skills and knowledge (g = 0.72; 99% CI = 0.53-0.90), psychological well-being (g = 0.52; 99% CI = 0.34-0.71), and interpersonal family relations (g = 0.76; 99% CI = 0.32-1.20).

INTERPRETATION: Caregiver skills training programs benefit both caregivers and children with neurodevelopmental disorders. Skills training programs improve child development and behavior, improve parenting skills, reduce caregiver mental health issues, and improve family functioning. Programs using culturally appropriate training material to improve the development, functioning, and participation of children within families and communities should be considered when caring for children with neurodevelopmental disorders.
AD  - Reichow, Brian. AJ Pappanikou Center for Excellence in Developmental Disabilities Education, Research, and Service, University of Connecticut Health Center, Farmington, CT, USA.Reichow, Brian. University of Florida, Gainesville, FL, USA.Kogan, Cary. University of Ottawa, Ottawa, ON, Canada.Barbui, Corrado. World Health Organization Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Section of Psychiatry, Department of Public Health and Community Medicine, University of Verona, Verona, Italy.Maggin, Daniel. University of Illinois at Chicago, Chicago, IL, USA.Salomone, Erica. University of Milano-Bicocca, Milan, Italy.Smith, Isaac C. AJ Pappanikou Center for Excellence in Developmental Disabilities Education, Research, and Service, University of Connecticut Health Center, Farmington, CT, USA.Smith, Isaac C. Yale University, New Haven, CT, USA.Smith, Isaac C. Virginia Tech, Blacksburg, VA, USA.Yasamy, M Taghi. World Health Organization, Geneva, Switzerland.Servili, Chiara. World Health Organization, Geneva, Switzerland.
AN  - 37786292
AU  - Reichow,
AU  - B.
AU  - Kogan,
AU  - C.
AU  - Barbui,
AU  - C.
AU  - Maggin,
AU  - D.
AU  - Salomone,
AU  - E.
AU  - Smith,
AU  - I.
AU  - C.
AU  - Yasamy,
AU  - M.
AU  - T.
AU  - Servili,
AU  - C.
DA  - Oct 02
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/dmcn.15764
DP  - Ovid Technologies
J2  - Dev Med Child Neurol
L1  - internal-pdf://2129812650/Reichow-2023-Caregiver skills training for car.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingOctReichow, BrianKogan, CaryBarbui, CorradoMaggin, DanielSalomone, EricaSmith, Isaac CYasamy, M TaghiServili, Chiara
PY  - 2023
SP  - 02
T2  - Developmental Medicine &amp; Child Neurology
TI  - Caregiver skills training for caregivers of individuals with neurodevelopmental disorders: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37786292
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37786292&amp;id=doi:10.1111%2Fdmcn.15764&amp;issn=0012-1622&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2023&amp;title=Developmental+Medicine+%26+Child+Neurology&amp;atitle=Caregiver+skills+training+for+caregivers+of+individuals+with+neurodevelopmental+disorders%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Reichow&amp;pid=%3Cauthor%3EReichow+B%3C%2Fauthor%3E%3CAN%3E37786292%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dmcn.15764?download=true
VL  - 02
ER  -
TY  - JOUR
AB  - **Background**
Schools are sites of dating and relationship violence (DRV) and of gender-based violence (GBV) victimization and perpetration. School-based interventions can reach a broad range of students, targeting both individual and group processes that may underpin DRV and GBV. Considering DRV and GBV jointly is important because of their shared etiologies. Comparing the effectiveness of interventions using network meta-analysis (NMA) can support decision-making on optimal resource use. 

**Objectives**

To evaluate the comparative effectiveness of school-based interventions for children aged 5 to 18 years on DRV and GBV victimization, perpetration, and related mediators. 

**Search Methods** 
We searched 21 databases in July 2020 and June 2021, alongside extensive supplementary search methods, including gray literature searches, forward and backward citation chasing, and searches on first and last author names. 

**Selection Criteria**
We included randomized-controlled trials of interventions for children of compulsory school age implemented within the school setting, and either partially or wholly aimed at changing DRV or GBV outcomes. 

**Data Collection and Analysis**
Pairwise meta-analyses using random-effects robust variance estimation considered intervention effectiveness on DRV and GBV victimization and perpetration using odds ratios, and on mediators (e.g., knowledge and attitudes) using standardized mean differences. Effects were divided into short-term (&lt; 12 months postbaseline) and long-term (&gt;= 12 months postbaseline). NMAs on victimization and perpetration outcomes compared interventions categorized by breadth of mechanism and complexity of delivery and implementation. Meta-regression tested sensitivity to percentage of girls in the trial sample and country context. 

**Main Results**
Our analysis included 68 trials. Evidence was stronger overall for effects on DRV than for GBV, with significant long-term impacts on DRV victimization (odds ratio [OR] = 0.82; 95% confidence interval [CI] = 0.68, 0.99) and DRV perpetration (OR = 0.78; 95% CI = 0.64, 0.94). Knowledge and attitudinal effects were predominantly short-term (e.g., for DRV-related violence acceptance, d = 0.16; 95% CI = 0.08, 0.24). NMAs did not suggest the superiority of any intervention type; however, most analyses for GBV outcomes were inconsistent. A higher proportion of girls in the sample was associated with increased effectiveness on long-term victimization outcomes. 

**Author&#039;s Conclusions**
 Evidence is stronger for DRV than for GBV, despite considerable heterogeneity. Certainty of findings was low or very low overall. 

**Public Health Implications**
Violence reductions may require more than 1 school year to become apparent. More extensive interventions may not be more effective. A possible reason for stronger effectiveness for DRV is that whereas GBV is ingrained in school cultures and practices, DRV is potentially more open to change via addressing individual knowledge and attitudes. (Am J Public Health. 2023;113(3):320-330. https://doi.org/10.2105/10.2105/AJPH.2022.307153).
AN  - 36791352
AU  - Farmer,
AU  - C.
AU  - Shaw,
AU  - N.
AU  - Rizzo,
AU  - A.
AU  - J.
AU  - Orr,
AU  - N.
AU  - Chollet,
AU  - A.
AU  - Hagell,
AU  - A.
AU  - Rigby,
AU  - E.
AU  - Young,
AU  - H.
AU  - Berry,
AU  - V.
AU  - Bonell,
AU  - C.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2105/AJPH.2022.307153
L1  - internal-pdf://1911404569/ajph.2022.307153.cleaned (1).pdf
PY  - 2023
SP  - 320-330
T2  - American Journal of Public Health
TI  - School-Based Interventions to Prevent Dating and Relationship Violence and Gender-Based Violence: Systematic Review and Network Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36791352
VL  - 113
ER  -
TY  - JOUR
AB  - The purpose of this review was to assess the effectiveness of tablet-based speech-generating devices (SGDs) in improving communication skills for individuals with autism spectrum disorder (ASD). A total of 31 single-case design intervention studies involving 84 individuals with ASD were reviewed and included in the analysis. We calculated Tau-U to evaluate the impact of interventions involving tablet-based SGDs on four different communication responses: specifically, mands, intraverbals, tacts, and vocalizations. To explore potential moderating variables for mand outcomes, we used the Kruskal-Wallis one-way test. The analysis revealed that interventions utilizing tablet-based SGDs led to improvements in communication responses. Specifically, large to very large changes were observed in mand and intraverbal responses, whereas moderate changes were noted in tact responses and vocalizations. The findings of this review underscore the potential of tablet-based SGDs in enhancing communication among individuals with ASD. We discuss the findings and provide implications for future research and practice.
AN  - WOS:001110338100001
AU  - Muharib,
AU  - R.
AU  - Walker,
AU  - V.
AU  - Dunn,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s10803-023-06173-6
L1  - internal-pdf://1695431595/Muharib-2023-Effects of Interventions Involvin.pdf
PY  - 2023
SP  - 19
T2  - Journal of Autism and Developmental Disorders
TI  - Effects of Interventions Involving Tablet-Based Speech-Generating Devices for Individuals with ASD: A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001110338100001
UR  - https://link.springer.com/article/10.1007/s10803-023-06173-6
UR  - https://link.springer.com/content/pdf/10.1007/s10803-023-06173-6.pdf
ER  -
TY  - JOUR
AB  - **Background:** 
Violence against children affects over one billion children globally. International organisations promote parenting interventions as a main strategy to reduce violence against children. Parenting interventions have therefore been implemented rapidly across the globe. Yet, evidence for their longer-term effects remains unclear. We integrated global evidence to estimate effects over time of parenting interventions to reduce physical and emotional violence against children.

**Methods:** 
In this systematic review and meta-analysis, we searched 26 databases and trial registries (14 non-English: Spanish, Chinese, Farsi, Russian, Thai) and conducted an extensive grey literature search up to August 01, 2022. We included randomised controlled trials (RCTs) of parenting interventions based on social learning theory for parents of children aged 2-10 years, without time or context restrictions. We critically appraised studies using Cochrane&#039;s Risk of Bias Tool. Data were synthesised using robust variance estimation meta-analyses. This study is registered with PROSPERO, CRD42019141844.

**Findings:** 
We screened 44,411 records and included 346 RCTs. Sixty RCTs reported outcomes on physical or emotional violence. Trials were distributed across 22 countries (22% LMICs). Risk of bias was high for various domains. Outcome data ranged from 0 weeks to 2 years after the intervention, and was largely based on parent self-report. Parenting interventions reduced physical and emotional violent parenting behaviours immediately after the intervention (n = 42, k = 59; d = -0.46; 95% CI: -0.59, -0.33), at 1-6 months follow-up (n = 18, k = 31; d = -0.24; 95% CI: -0.37, -0.11) and at 7-24 months follow-up (n = 12, k = 19; d = -0.18; 95% CI: -0.34, -0.02), but effects were smaller over time.

**Interpretation:** 
Our findings suggest that parenting interventions can reduce physical and emotional violence against children. Effects are maintained up to 24 months follow-up, but with diminished effect sizes. With global policy interest and imminent importance, research beyond 2 years and how effects can be better sustained over time is urgently needed.

Funding: Student scholarship from the Economic Social Research Council, Clarendon, and Wolfson Isaiah Berlin Fund. Copyright &copy; 2023 The Author(s).
AU  - Backhaus,
AU  - S.
AU  - Leijten,
AU  - P.
AU  - Jochim,
AU  - J.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Gardner,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.eclinm.2023.102003
L1  - internal-pdf://3112402298/Backhaus-2023-Effects over time of parenting i.pdf
PY  - 2023
SP  - 102003
T2  - EClinicalMedicine
TI  - Effects over time of parenting interventions to reduce physical and emotional violence against children: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=pmnm&amp;NEWS=N&amp;AN=37251634
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209692/pdf/main.pdf
VL  - 60
ER  -
TY  - JOUR
AB  - **Background**
School-based law enforcement (SBLE) has become a common intervention. Although SBLE is meant to make schools safer, critics suggest it may not accomplish this purpose, and may have unintended negative consequences such as increasing students&rsquo; exclusionary discipline or contact with the criminal justice system. There may also be secondary effects related to perceptions of the school or student learning.

**Objectives**
The purpose of this review is to synthesize the literature evaluating the use of SBLE, including outcomes related to (a) crime and behavior problems; (b) perceptions of safety; and (c) learning.

**Methods**
We conducted a systematic literature search to identify studies that examined outcomes associated with SBLE use. Eligible studies used experimental or quasi-experimental designs; included samples of students, teachers/staff, schools, or school districts; reported on a policing strategy focused on crime prevention or school safety that did not involve officers teaching a curriculum; included a measure that reflects crime and behavior problems, perceptions of safety, or learning; and were in a primary or secondary school. Following a multi-stage screening process to identify studies eligible for inclusion, we estimated a series of meta-analytic models with robust variance estimation to calculate weighted mean effect sizes for each of three main categories of outcomes and commonly occurring subsets of these categories. We examined heterogeneity in these estimates across features of the primary studies&rsquo; design.

**Results**
The search and screening process yielded 1002 effect sizes from 32 reports. There were no true experiments, and the quasi-experiments ranged from strictly correlational to permitting stronger causal inferences. SBLE use was associated with greater crime and behavior problems in studies that used schools as the unit of analysis. Within this category, SBLE use was associated with increased exclusionary discipline among studies that used both schools (g&thinsp;=&thinsp;0.15, 95% confidence interval [CI] [0.02, 0.27]) and students (g&thinsp;=&thinsp;0.003, 95% CI [0.002, 0.003]) as the unit of analysis. SBLE use was not associated with any measures of crime or violence in schools. SBLE use was associated with greater feelings of safety among studies that used schools as the unit of analysis (g&thinsp;=&thinsp;0.18, 95% CI [0.13, 0.24]), although this estimate was based on only seven effect sizes from two correlational studies. All the other models, including those examining learning outcomes, yielded null results. None of the moderators tested showed meaningful relationships, indicating the findings were consistent across a variety of study design features.

**Authors&rsquo; Conclusions**
This study&#039;s findings provide no evidence that there is a safety-promoting component of SBLE, and support the criticism that SBLE criminalizes students and schools. Although we found no evidence of differences across methodological features, risk of bias in the primary studies limits our confidence in making causal inferences. To the extent that the findings are causal, schools that invest in strategies to improve safety will likely benefit from divesting from SBLE and instead investing in evidence-based strategies for enhancing school safety. Schools that continue to use SBLE should ensure that their model has no harmful effects and is providing safety benefits.
AU  - Fisher,
AU  - B.
AU  - W.
AU  - Petrosino,
AU  - A.
AU  - Persson,
AU  - H.
AU  - Guckenburg,
AU  - S.
AU  - Fronius,
AU  - T.
AU  - Benitez,
AU  - I.
AU  - Earl,
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1002/cl2.1360
L1  - internal-pdf://0160634945/Campbell Systematic Reviews - 2023 - Fisher -.pdf
PY  - 2023
T2  - Campbell Systematic Reviews
TI  - School-based law enforcement strategies to reduce crime, increase perceptions of safety, and improve learning outcomes in primary and secondary schools: A systematic review
ER  -
TY  - JOUR
AB  - **Objectives**
The present study tested the efficacy of parenting program components in reducing disruptive or delinquent child behaviors at first post-treatment for families with children in early versus middle childhood. 

**Methods**
Eighty-five studies were identified, containing five parenting components (Psychoeducation [PE], Behavior management [BM], Relationship enhancement [RE], Parental self-management [SM], and Parent as a coach [PC]). 

**Results**
For both early and middle childhood, four parenting program components were effective, namely (1) BM, (2) BM with RE, (3) BM with SM, and (4) BM with PE and RE and SM and PC. However, BM with RE and SM, as well as BM with PE and RE and SM, were effective during early childhood. BM with RE appeared to be the most beneficial intervention during early childhood, while BM was most effective during middle childhood. 

**Conclusion**
The evidence highlights the need to implement different programmatic components developmentally, during early versus middle childhood. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-61795-001
AU  - Tehrani,
AU  - H.
AU  - D.
AU  - Yamini,
AU  - S.
AU  - Vazsonyi,
AU  - A.
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s11292-023-09562-0
L1  - internal-pdf://3174128370/Tehrani-2023-The effectiveness of parenting pr.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Journal of Experimental Criminology
TI  - The effectiveness of parenting program components on disruptive and delinquent behaviors during early and middle childhood: A component network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-61795-001
UR  - https://link.springer.com/article/10.1007/s11292-023-09562-0
UR  - https://link.springer.com/content/pdf/10.1007/s11292-023-09562-0.pdf
ER  -
TY  - JOUR
AB  - **Background:** 
Non-stimulant guanfacine is a common second-line medication for attention-deficit hyperactivity disorder (ADHD). Numerous randomized controlled trials (RCTs) have explored the efficacy of guanfacine in ADHD treatment. This meta-analysis combined data from selected RCTs to analyze the efficacy and safety of guanfacine in treating ADHD. 

**Methods:** 
RCTs were identified from published sources through searches in PubMed, Cochrane Library, Web of Science, and Embase (up to February 2022), defining the Clinical Global Impression of Improvement (CGI-I) treatment response score of &lt;=2 as the primary outcome. Subgroup analysis was performed with a bound treatment duration of 10 weeks. Safety was defined by treatment-emergent adverse events (TEAEs). 

**Results:**
Twelve out of 332 studies with 2653 participants were included. All studies compared guanfacine with placebos. Guanfacine was significantly more effective in treating ADHD (Risk Ratio [RR] 1.78, 95% CI: 1.59-2.01). In the &lt;10 weeks subgroup, the efficacy in the guanfacine group compared with the placebo group was 58.5% versus 29.4%, respectively (RR 1.97, 95% CI: 1.71-2.26). In the &gt;10 weeks subgroup, the efficacy in the guanfacine group compared with the placebo group was 63.6% versus 39.7%, respectively (RR 1.57, 95% CI: 1.37-1.79). Both subgroups lacked heterogeneity (I&lt;sup&gt;2&lt;/sup&gt; = 0), and a funnel plot showed a low publication bias risk. Around 80% of participants in the guanfacine group experienced at least one TEAE, compared with 66.5% in the placebo group (RR 1.23, 95% CI: 1.14-1.32), with low heterogeneity (I&lt;sup&gt;2&lt;/sup&gt; = 46, p = 0.05). The most common TEAEs in the guanfacine group were somnolence (38.6%), headaches (20.5%), and fatigue (15.2%). 

**Conclusions:**
Guanfacine is safe and effective for treating ADHD, with no serious adverse events. Guanfacine should be considered as an effective treatment option where effectiveness or tolerability of the central nervous system stimulant is of concern. There is stronger evidence of efficacy for children; more clinical studies are needed for adults.
AN  - 36944092
AU  - Yu,
AU  - S.
AU  - Shen,
AU  - S.
AU  - Tao,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1089/cap.2022.0038
L1  - internal-pdf://2931288516/Yu_2023.pdf
PY  - 2023
SP  - 40-50
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Guanfacine for the Treatment of Attention-Deficit Hyperactivity Disorder: An Updated Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36944092
UR  - https://www.liebertpub.com/doi/10.1089/cap.2022.0038
VL  - 33
ER  -
TY  - JOUR
AB  - BACKGROUND: Mental health problems among young people are a major global public health challenge. Psychological interventions may improve mental health, yet most are developed in western cultures, and it is unclear whether they are applicable to other geographical settings and can be delivered successfully to diverse populations. We identified empirical studies focusing upon cross-culturally adapted psychological interventions and examined the cultural adaptation process used and the effectiveness of the interventions in the treatment of depression and/or anxiety disorders among young people (defined here as children and adolescents aged between 8-18 years).

METHOD: We conducted a scoping review aligning to the guidelines reported in the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Reviews (PRISMA-ScR) Statement. Stakeholder engagement enabled us to discuss the findings of the review and obtain feedback.

RESULTS: We identified 17 studies of cross-culturally adapted psychological interventions that considered the appropriate language, metaphors, culturally appropriate terms, and cultural values of young people. Most studies (n = 11) adopted a randomised control trial (RCT) methodology. Six studies used the ecological validity and cultural sensitivity framework. Planned adaptation, cultural adaptation of content, and surface and deep structure level adaptations were used in other studies. Apart from one pilot study, all studies reported that culturally adapted interventions resulted in improvements in depression and/or anxiety symptoms in young people. The results suggest the potential effectiveness of cross-culturally adapted interventions within this context. Our stakeholder consultations demonstrated that engaging different community-level stakeholders in the adaptation process was highly recommended.

CONCLUSIONS: Whilst most included studies indicated improvements in depression and/or anxiety symptoms in young people following a cross-culturally adapted intervention, more work is needed in this area. In particular, focus should be placed upon identifying the dimensions of interventions that should be culturally adapted to make them acceptable, engaging and effective.
AD  - Mishu, Masuma Pervin. Institute of Epidemiology and Health Care, University College London, London, United Kingdom.Tindall, Lucy. Department of Health Sciences, Faculty of Sciences, University of York, York, United Kingdom.Kerrigan, Philip. Department of Health Sciences, Faculty of Sciences, University of York, York, United Kingdom.Gega, Lina. Department of Health Sciences, Faculty of Sciences, University of York, York, United Kingdom.Gega, Lina. Hull York Medical School, University of York, York, United Kingdom.
AN  - 37878658
AU  - Mishu,
AU  - M.
AU  - P.
AU  - Tindall,
AU  - L.
AU  - Kerrigan,
AU  - P.
AU  - Gega,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0290653
DP  - Ovid Technologies
J2  - PLoS ONE
KW  - Adolescent
KW  - Child
KW  - Humans
KW  - Depression/th [Therapy]
KW  - *Depression
KW  - *Psychosocial Intervention
KW  - Anxiety/th [Therapy]
KW  - Anxiety Disorders/th [Therapy]
KW  - Mental Health
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://3721025589/Mishu-2023-Cross-culturally adapted psychologi.pdf
LA  - English
M3  - Systematic Review
Review
N1  - Mishu, Masuma PervinTindall, LucyKerrigan, PhilipGega, Lina
PY  - 2023
SP  - e0290653
T2  - PLoS ONE [Electronic Resource]
TI  - Cross-culturally adapted psychological interventions for the treatment of depression and/or anxiety among young people: A scoping review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=37878658
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37878658&amp;id=doi:10.1371%2Fjournal.pone.0290653&amp;issn=1932-6203&amp;isbn=&amp;volume=18&amp;issue=10&amp;spage=e0290653&amp;pages=e0290653&amp;date=2023&amp;title=PLoS+ONE+%5BElectronic+Resource%5D&amp;atitle=Cross-culturally+adapted+psychological+interventions+for+the+treatment+of+depression+and%2For+anxiety+among+young+people%3A+A+scoping+review.&amp;aulast=Mishu&amp;pid=%3Cauthor%3EMishu+MP%3C%2Fauthor%3E%3CAN%3E37878658%3C%2FAN%3E%3CDT%3ESystematic+Review%3C%2FDT%3E
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0290653&amp;type=printable
VL  - 18
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
To summarize the breadth and quality of evidence supporting commonly recommended early childhood autism interventions and their estimated effects on developmental outcomes. 

**DESIGN**
Updated systematic review and meta-analysis (autism intervention meta-analysis; Project AIM). 

**DATA SOURCES**
A search was conducted in November 2021 (updating a search done in November 2017) of the following databases and registers: Academic Search Complete, CINAHL Plus with full text, Education Source, Educational Administration Abstracts, ERIC, Medline, ProQuest Dissertations and Theses, PsycINFO, Psychology and Behavioral Sciences Collection, and SocINDEX with full text, Trials, and ClinicalTrials.gov.

**ELIGIBILITY CRITERIA FOR SELECTING STUDIES**
Any controlled group study testing the effects of any non-pharmacological intervention on any outcome in young autistic children younger than 8 years. 

**REVIEW METHODS**
Newly identified studies were integrated into the previous dataset and were coded for participant, intervention, and outcome characteristics. Interventions were categorized by type of approach (such as behavioral, developmental, naturalistic developmental behavioral intervention, and technology based), and outcomes were categorized by domain (such as social communication, adaptive behavior, play, and language). Risks of bias were evaluated following guidance from Cochrane. Effects were estimated for all intervention and outcome types with sufficient contributing data, stratified by risk of bias, using robust variance estimation to account for intercorrelation of effects within studies and subgroups. 

**RESULTS**
The search yielded 289 reports of 252 studies, representing 13 304 participants and effects for 3291 outcomes. When contributing effects were restricted to those from randomized controlled trials, significant summary effects were estimated for behavioral interventions on social emotional or challenging behavior outcomes (Hedges&#039; g=0.58, 95% confidence interval 0.11 to 1.06; P=0.02), developmental interventions on social communication (0.28, 0.12 to 0.44; P=0.003); naturalistic developmental behavioral interventions on adaptive behavior (0.23, 0.02 to 0.43; P=0.03), language (0.16, 0.01 to 0.31; P=0.04), play (0.19, 0.02 to 0.36; P=0.03), social communication (0.35, 0.23 to 0.47; P&lt;0.001), and measures of diagnostic characteristics of autism (0.38, 0.17 to 0.59; P=0.002); and technology based interventions on social communication (0.33, 0.02 to 0.64; P=0.04) and social emotional or challenging behavior outcomes (0.57, 0.04 to 1.09; P=0.04). When effects were further restricted to exclude caregiver or teacher report outcomes, significant effects were estimated only for developmental interventions on social communication (0.31, 0.13 to 0.49; P=0.003) and naturalistic developmental behavioral interventions on social communication (0.36, 0.23 to 0.49; P&lt;0.001) and measures of diagnostic characteristics of autism (0.44, 0.20 to 0.68; P=0.002). When effects were then restricted to exclude those at high risk of detection bias, only one significant summary effect was estimated-naturalistic developmental behavioral interventions on measures of diagnostic characteristics of autism (0.30, 0.03 to 0.57; P=0.03). Adverse events were poorly monitored, but possibly common. 

**CONCLUSION**
The available evidence on interventions to support young autistic children has approximately doubled in four years. Some evidence from randomized controlled trials shows that behavioral interventions improve caregiver perception of challenging behavior and child social emotional functioning, and that technology based interventions support proximal improvements in specific social communication and social emotional skills. Evidence also shows that developmental interventions improve social communication in interactions with caregivers, and naturalistic developmental behavioral interventions improve core challenges associated with autism, particularly difficulties with social communication. However, potential benefits of these interventions cannot be weighed against the potential for adverse effects owing to inadequate monitoring and reporting.
AN  - 37963634
AU  - Sandbank,
AU  - M.
AU  - Bottema-Beutel,
AU  - K.
AU  - Crowley
AU  - LaPoint,
AU  - S.
AU  - Feldman,
AU  - J.
AU  - I.
AU  - Barrett,
AU  - D.
AU  - J.
AU  - Caldwell,
AU  - N.
AU  - Dunham,
AU  - K.
AU  - Crank,
AU  - J.
AU  - Albarran,
AU  - S.
AU  - Woynaroski,
AU  - T.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1136/bmj-2023-076733
L1  - internal-pdf://2179801277/Sandbank-2023-Autism intervention meta-analysi.pdf
PY  - 2023
SP  - e076733
T2  - BMJ
TI  - Autism intervention meta-analysis of early childhood studies (Project AIM): updated systematic review and secondary analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37963634
UR  - https://www.bmj.com/content/bmj/383/bmj-2023-076733.full.pdf
VL  - 383
ER  -
TY  - JOUR
AB  - **Simple Summary** 
Executive functions are cognitive processing skills associated with planning, problem-solving, decision making, and regulating behaviour. For some individuals these abilities may be impaired, which can have negative long-term impacts. It has been proposed that interacting with animals may provide an opportunity to strengthen these skills. A systematic review was carried out to assess the ways in which interacting with animals may improve executive functions. This review included 23 studies exploring executive functions across three contexts: the human-pet relationship, the presence of an animal, and involvement in an animal-assisted service. There is some evidence to suggest that interacting with an animal may be beneficial for older adults, whilst horseback riding seems particularly beneficial for children; however, the overall methodological rigour is limited. 

**Abstract**
There has been growing interest in the potential benefits of using human-animal interactions to improve executive functions: cognitive processes that allow individuals to plan, solve problems, and self-regulate behaviour. To date, no comprehensive review has been conducted. The purpose of this study was to evaluate existing literature, adopting broad inclusion criteria. Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, 16 papers were identified from peer-reviewed literature. Additional papers were identified from grey literature, including 6 dissertations and 1 thesis. A review of these 23 studies found that human-animal interactions and executive functions are investigated in three main ways: (1) exploring the potential benefits of the human-pet relationship, (2) exploring the impact of an animal&#039;s presence during administration of executive function tests, and (3) evaluating the efficacy of animal-assisted services (e.g., animal-assisted therapy) on executive functions. Five of the included studies reported a significant improvement across all measured domains of executive functions, but effect sizes were underreported. Comparatively, 9 studies reported mixed findings, d = 0.32-0.55, while 8 studies reported no significant results. The overall rigour of the research was limited, with great heterogeneity between the study methodologies and outcome measures used. It is recommended that future studies utilise high-quality research methodologies through the use of randomisation, pre- and postmeasures, and appropriate control conditions, where possible.
AN  - WOS:001028151800001
AU  - Tepper,
AU  - D.
AU  - Shnookal,
AU  - J.
AU  - Howell,
AU  - T.
AU  - Bennett,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3390/ani13132080
L1  - internal-pdf://0586264689/Tepper-2023-Can Interacting with Animals Impro.pdf
PY  - 2023
SP  - 21
T2  - Animals
TI  - Can Interacting with Animals Improve Executive Functions? A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001028151800001
UR  - https://mdpi-res.com/d_attachment/animals/animals-13-02080/article_deploy/animals-13-02080-v2.pdf?version=1687671376
VL  - 13
ER  -
TY  - JOUR
AB  - Reviews into universal interventions to improve help seeking in young people focus on specific concepts, such as behaviour, do not differentiate between interpersonal and intrapersonal help seeking, and often report on statistical significance, rather than effect size. The aim of this review was to address the gaps highlighted above, to investigate the impact of universal, school-based interventions on help-seeking in children and young people, as well as to explore longer term impact. Four databases were searched. Data were extracted on country of origin, design, participant, school, and intervention characteristics, the help-seeking concept measured (e.g. knowledge, attitude/intention, behaviour), the duration between baseline and each follow-up (if applicable) and effect sizes at each follow-up. Quality assessment of the studies was undertaken using the Effective Public Health Practice Project (EPHPP) quality assessment tool. Overall, 14 different interventions met inclusion criteria. The majority of the studies were rated low in the quality assessment. Three constructs were most frequently reported a) intrapersonal attitudes towards help-seeking, b) interpersonal attitudes towards help-seeking and c) intrapersonal intended help-seeking. Findings around intervention effect were mixed. There was tentative evidence that interventions impacting interpersonal attitudes produced small effect sizes when measured between 3 and 6 months post intervention and that when effect sizes were initially observed intrapersonal attitudes, this remained at 3-6 month follow-up. Further work should pay attention to implementation factors, understanding the core ingredients needed to deliver effective interventions and whether embedding mental health education could help sustain or top up effect sizes from help-seeking interventions.
AN  - 36637482
AU  - Hayes,
AU  - D.
AU  - Mansfield,
AU  - R.
AU  - Mason,
AU  - C.
AU  - Santos,
AU  - J.
AU  - Moore,
AU  - A.
AU  - Boehnke,
AU  - J.
AU  - Ashworth,
AU  - E.
AU  - Moltrecht,
AU  - B.
AU  - Humphrey,
AU  - N.
AU  - Stallard,
AU  - P.
AU  - Patalay,
AU  - P.
AU  - Deighton,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s00787-022-02135-y
L1  - internal-pdf://1480039988/Hayes-2023-The impact of universal, school bas.pdf
PY  - 2023
SP  - 13
T2  - European Child &amp; Adolescent Psychiatry
TI  - The impact of universal, school based, interventions on help seeking in children and young people: a systematic literature review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36637482
UR  - https://link.springer.com/content/pdf/10.1007/s00787-022-02135-y.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - BACKGROUND: This study aimed to analyze the efficacy of resilience-promoting interventions among adolescents and youth aged 10-24 years with any type of diabetes. 

METHODS: A systematic literature search was performed using the PubMed, Web of Science, Embase, Cochrane Library, CINAHL, and PsycINFO databases from inception to May 25, 2022. The Cochrane risk of bias tool (version 2) was used to assess the quality of the included studies. A meta-analysis was performed to calculate the pooled effects of resilience-promoting interventions. 

RESULTS: Nineteen articles were included covering an overall sample of 2048 adolescents with diabetes. When analyzing the effectiveness of resilience-promoting interventions, hemoglobin A1c (HbA1c) at six months [mean difference = - 0.47, 95% confidence interval (CI) = - 0.83 to - 0.12, P = 0.009] after the intervention was improved. However, long-term (&gt;= 12 months) improvement in HbA1c was not significant. In addition, comparing the control group, there were significant differences in the effect size for stress [standardized mean difference (SMD) = - 0.87, 95% CI = - 1.25 to -0.48, P &lt; 0.05], self-efficacy (SMD = 0.50, 95% CI = 0.02-0.98, P = 0.04) and quality of life (SMD = 0.27, 95% CI = 0.03-0.51, P = 0.03). 

CONCLUSIONS: Resilience-promoting intervention is a promising way for adolescent diabetes management to improve HbA1c, stress, self-efficacy, and quality of life. Incorporating resilience-promoting components into diabetes education and re-enforcing these contents every six months are recommended for implementation in clinical practice.
AN  - 36534296
AU  - Wu,
AU  - Y.
AU  - Zhang,
AU  - Y.
AU  - Y.
AU  - Zhang,
AU  - Y.
AU  - T.
AU  - Zhang,
AU  - H.
AU  - J.
AU  - Long,
AU  - T.
AU  - X.
AU  - Zhang,
AU  - Q.
AU  - Huang,
AU  - J.
AU  - Li,
AU  - M.
AU  - Z.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12519-022-00666-7
L1  - internal-pdf://1352981591/Wu-2023-Effectiveness of resilience-promoting.pdf
PY  - 2023
SP  - 323-339
T2  - World Journal of Pediatrics
TI  - Effectiveness of resilience-promoting interventions in adolescents with diabetes mellitus: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36534296
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9761642/pdf/12519_2022_Article_666.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - **Background:** 
Strategies to reduce alcohol consumption would contribute to substantial health benefits in the population, including reducing cancer risk. The increasing accessibility and applicability of digital technologies make these powerful tools suitable to facilitate changes in behaviour in young people which could then translate into both immediate and long-term improvements to public health. 

**Objective:** 
We conducted a review of systematic reviews to assess the available evidence on digital interventions aimed at reducing alcohol consumption in sub-populations of young people [school-aged children, college/university students, young adults only (over 18 years) and both adolescent and young adults (&lt;25 years)]. Methods: Searches were conducted across relevant databases including KSR Evidence, Cochrane Database of Systematic Reviews (CDSR) and Database of Abstracts of Reviews of Effects (DARE). Records were independently screened by title and abstract and those that met inclusion criteria were obtained for full text screening by two reviewers. Risk of bias (RoB) was assessed with the ROBIS checklist. We employed a narrative analysis. 

**Results:** 
Twenty-seven systematic reviews were included that addressed relevant interventions in one or more of the sub-populations, but those reviews were mostly assessed as low quality. Definitions of &quot;digital intervention&quot; greatly varied across systematic reviews. Available evidence was limited both by sub-population and type of intervention. No reviews reported cancer incidence or influence on cancer related outcomes. In school-aged children eHealth multiple health behaviour change interventions delivered through a variety of digital methods were not effective in preventing or reducing alcohol consumption with no effect on the prevalence of alcohol use [Odds Ratio (OR) = 1.13, 95% CI: 0.95-1.36, review rated low RoB, minimal heterogeneity]. While in adolescents and/or young adults who were identified as risky drinkers, the use of computer or mobile device-based interventions resulted in reduced alcohol consumption when comparing the digital intervention with no/minimal intervention (-13.4 g/week, 95% CI: -19.3 to -7.6, review rated low RoB, moderate to substantial heterogeneity). In University/College students, a range of E-interventions reduced the number of drinks consumed per week compared to assessment only controls although the overall effect was small [standardised mean difference (SMD): -0.15, 95% CI: -0.21 to -0.09]. Web-based personalised feedback interventions demonstrated a small to medium effect on alcohol consumption (SMD: -0.19, 95% CI: -0.27 to -0.11) (review rated high RoB, minimal heterogeneity). In risky drinkers, stand-alone Computerized interventions reduced short (SMD: -0.17, 95% CI: -0.27 to -0.08) and long term (SMD: -0.17, 95% CI: -0.30 to -0.04) alcohol consumption compared to no intervention, while a small effect (SMD: -0.15, 95% CI: -0.25 to -0.06) in favour of computerised assessment and feedback vs. assessment only was observed. No short-term (SMD: -0.10, 95% CI: -0.30 to 0.11) or long-term effect (SMD: -0.11, 95% CI: -0.53 to 0.32) was demonstrated for computerised brief interventions when compared to counsellor based interventions (review rated low RoB, minimal to considerable heterogeneity). In young adults and adolescents, SMS-based interventions did not significantly reduce the quantity of drinks per occasion from baseline (SMD: 0.28, 95% CI: -0.02 to 0.58) or the average number of standard glasses per week (SMD: -0.05, 95% CI: -0.15 to 0.05) but increased the risk of binge drinking episodes (OR = 2.45, 95% CI: 1.32-4.53, review rated high RoB; minimal to substantial heterogeneity). For all results, interpretation has limitations in terms of risk of bias and heterogeneity. 

**Conclusions:** 
Limited evidence suggests some potential for digital interventions, particularly those with feedback, in reducing alcohol consumption in certain sub-populations of younger people. However, this effect is often small, inconsistent or diminishes when only methodologically robust evidence is considered. There is no systematic review evidence that digital interventions reduce cancer incidence through alcohol moderation in young people. To reduce alcohol consumption, a major cancer risk factor, further methodologically robust research is warranted to explore the full potential of digital interventions and to form the basis of evidence based public health initiatives.
AN  - 37288171
AU  - McDermott,
AU  - K.
AU  - T.
AU  - Noake,
AU  - C.
AU  - Wolff,
AU  - R.
AU  - Espina,
AU  - C.
AU  - Foucaud,
AU  - J.
AU  - Steindorf,
AU  - K.
AU  - Schuz,
AU  - J.
AU  - Thorat,
AU  - M.
AU  - A.
AU  - Weijenberg,
AU  - M.
AU  - Bauld,
AU  - L.
AU  - Kleijnen,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fdgth.2023.1178407
L1  - internal-pdf://2410928778/McDermott-2023-Digital interventions to modera.pdf
PY  - 2023
SP  - 1178407
T2  - Frontiers in Digital Health
TI  - Digital interventions to moderate alcohol consumption in young people: a Cancer Prevention Europe overview of systematic reviews
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37288171
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243367/pdf/fdgth-05-1178407.pdf
VL  - 5
ER  -
TY  - JOUR
AB  - **Background**
Infants born preterm are at increased risk of early hypernatraemia (above‐normal blood sodium levels) and late hyponatraemia (below‐normal blood sodium levels). There are concerns that imbalances of sodium intake may impact neonatal morbidities, growth and developmental outcomes.

**Objectives**
To determine the effects of higher versus lower sodium supplementation in preterm infants.

**Search methods**
We searched CENTRAL in February 2023; and MEDLINE, Embase and trials registries in March and April 2022. We checked reference lists of included studies and systematic reviews where subject matter related to the intervention or population examined in this review. We compared early (&lt; 7 days following birth), late (&ge; 7 days following birth), and early and late sodium supplementation, separately.

**Selection criteria**
We included randomised, quasi‐randomised or cluster‐randomised controlled trials that compared nutritional supplementation that included higher versus lower sodium supplementation in parenteral or enteral intake, or both. Eligible participants were preterm infants born before 37 weeks&#039; gestational age or with a birth weight less than 2500 grams, or both. We excluded studies that had prespecified differential water intakes between groups.

**Data collection and analysis**
Two review authors independently assessed eligibility and risk of bias, and extracted data. We used the GRADE approach to assess the certainty of evidence.

**Main results**
We included nine studies in total. However, we were unable to extract data from one study (20 infants); some studies contributed to more than one comparison. Eight studies (241 infants) were available for quantitative meta‐analysis. Four studies (103 infants) compared early higher versus lower sodium intake, and four studies (138 infants) compared late higher versus lower sodium intake. Two studies (103 infants) compared intermediate sodium supplementation (&ge; 3 mmol/kg/day to &lt; 5 mmol/kg/day) versus no supplementation, and two studies (52 infants) compared higher sodium supplementation (&ge; 5 mmol/kg/day) versus no supplementation. We assessed only two studies (63 infants) as low risk of bias.

Early (less than seven days following birth) higher versus lower sodium intake

Early higher versus lower sodium intake may not affect mortality (risk ratio (RR) 1.02, 95% confidence interval (CI) 0.38 to 2.72; I2 = 0%; 3 studies, 83 infants; low‐certainty evidence). Neurodevelopmental follow‐up was not reported. Early higher versus lower sodium intake may lead to a similar incidence of hyponatraemia &lt; 130 mmol/L (RR 0.68, 95% CI 0.40 to 1.13; I2 = 0%; 3 studies, 83 infants; low‐certainty evidence) but an increased incidence of hypernatraemia &ge; 150 mmol/L (RR 1.62, 95% CI 1.00 to 2.65; I2 = 0%; 4 studies, 103 infants; risk difference (RD) 0.17, 95% CI 0.01 to 0.34; number needed to treat for an additional harmful outcome 6, 95% CI 3 to 100; low‐certainty evidence). Postnatal growth failure was not reported. The evidence is uncertain for an effect on necrotising enterocolitis (RR 4.60, 95% CI 0.23 to 90.84; 1 study, 46 infants; very low‐certainty evidence). Chronic lung disease at 36 weeks was not reported.

Late (seven days or more following birth) higher versus lower sodium intake

Late higher versus lower sodium intake may not affect mortality (RR 0.13, 95% CI 0.01 to 2.20; 1 study, 49 infants; very low‐certainty evidence). Neurodevelopmental follow‐up was not reported. Late higher versus lower sodium intake may reduce the incidence of hyponatraemia &lt; 130 mmol/L (RR 0.13, 95% CI 0.03 to 0.50; I2 = 0%; 2 studies, 69 infants; RD &minus;0.42, 95% CI &minus;0.59 to &minus;0.24; number needed to treat for an additional beneficial outcome 2, 95% CI 2 to 4; low‐certainty evidence). The evidence is uncertain for an effect on hypernatraemia &ge; 150 mmol/L (RR 7.88, 95% CI 0.43 to 144.81; I2 = 0%; 2 studies, 69 infants; very low‐certainty evidence). A single small study reported that later higher versus lower sodium intake may reduce the incidence of postnatal growth failure (RR 0.25, 95% CI 0.09 to 0.69; 1 study; 29 infants; low‐certainty evidence). The evidence is uncertain for an effect on necrotising enterocolitis (RR 0.07, 95% CI 0.00 to 1.25; 1 study, 49 infants; very low‐certainty evidence) and chronic lung disease (RR 2.03, 95% CI 0.80 to 5.20; 1 study, 49 infants; very low‐certainty evidence).

Early and late (day 1 to 28 after birth) higher versus lower sodium intake for preterm infants

Early and late higher versus lower sodium intake may not have an effect on hypernatraemia &ge; 150 mmol/L (RR 2.50, 95% CI 0.63 to 10.00; 1 study, 20 infants; very low‐certainty evidence). No other outcomes were reported.

**Authors&#039; conclusions**
Early (&lt; 7 days following birth) higher sodium supplementation may result in an increased incidence of hypernatraemia and may result in a similar incidence of hyponatraemia compared to lower supplementation. We are uncertain if there are any effects on mortality or neonatal morbidity. Growth and longer‐term development outcomes were largely unreported in trials of early sodium supplementation.

Late (&ge; 7 days following birth) higher sodium supplementation may reduce the incidence of hyponatraemia. We are uncertain if late higher intake affects the incidence of hypernatraemia compared to lower supplementation. Late higher sodium intake may reduce postnatal growth failure. We are uncertain if late higher sodium intake affects mortality, other neonatal morbidities or longer‐term development.

We are uncertain if early and late higher versus lower sodium supplementation affects outcomes.
AU  - Diller,
AU  - N.
AU  - Osborn,
AU  - D.
AU  - A.
AU  - Birch,
AU  - P.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD012642.pub2
L1  - internal-pdf://2576159848/Diller_et_al-2023-Cochrane_Database_of_Systema.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Higher versus lower sodium intake for preterm infants
ER  -
TY  - JOUR
AB  - Vaping prevention messages are widely used to communicate the health harms and addiction risks of vaping and discourage vaping among adolescents and young adults. We conducted a meta-analysis of experimental studies to examine the effects of these messages and to understand their theoretical mechanisms. Systematic, comprehensive searches generated 4,451 references, among which 12 studies (cumulative N = 6,622) met inclusion criteria for the meta-analysis. Across these studies, a total of 35 different vaping-related outcomes were measured, and 14 outcomes assessed in two or more independent samples were meta-analyzed. Results showed that compared to control, exposure to vaping prevention messages led to higher vaping risk perceptions, including harm perceptions (d = 0.30, p &lt; .001), perceived likelihood of harm (d = 0.23, p &lt; .001), perceived relative harm (d = 0.14, p = .036), addiction perceptions (d = 0.39, p &lt; .001), perceived likelihood of addiction (d = 0.22, p &lt; .001), and perceived relative addiction (d = 0.33, p = .015). Also, compared to control, exposure to vaping prevention messages led to more vaping knowledge (d = 0.37, p &lt; .001), lower intentions to vape (d = -0.09, p = .022), and higher perceived message effectiveness (message perceptions; d = 0.57, p &lt; .001; effects perceptions; d = 0.55, p &lt; .001). Findings suggest vaping prevention messages have an impact, yet may operate through different theoretical mechanisms than cigarette pack warnings.
AN  - 36882378
AU  - Ma,
AU  - H.
AU  - Kieu,
AU  - T.
AU  - K.
AU  - Ribisl,
AU  - K.
AU  - M.
AU  - Noar,
AU  - S.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/10410236.2023.2185578
L1  - internal-pdf://2825174310/Ma.pdf
PY  - 2023
SP  - 1-14
T2  - Health Communication
TI  - Do Vaping Prevention Messages Impact Adolescents and Young Adults? A Meta-Analysis of Experimental Studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36882378
ER  -
TY  - JOUR
AB  - Many studies have explored the efficacy of probiotics on autism spectrum disorder (ASD) in children, but there is no consensus on the curative effect. This systematic review and meta-analysis aimed to comprehensively investigate whether probiotics could improve behavioral symptoms in children with ASD. A systematic database search was conducted and a total of seven studies were included in the meta-analysis. We found a nonsignificant overall effect size of probiotics on behavioral symptoms in children with ASD (SMD = -0.24, 95% CI: -0.60 to 0.11, p = 0.18). However, a significant overall effect size was found in the subgroup of the probiotic blend (SMD = -0.42, 95% CI: -0.83 to -0.02, p = 0.04). Additionally, these studies provided limited evidence for the efficacy of probiotics due to their small sample sizes, a shorter intervention duration, different probiotics used, different scales used, and poor research quality. Thus, randomized, double-blind, and placebo-controlled studies following strict trial guidelines are needed to precisely demonstrate the therapeutic effects of probiotics on ASD in children.
AN  - 36986145
AU  - He,
AU  - X.
AU  - Liu,
AU  - W.
AU  - Tang,
AU  - F.
AU  - Chen,
AU  - X.
AU  - Song,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/nu15061415
L1  - internal-pdf://2096931794/He-2023-Effects of Probiotics on Autism Spectr.pdf
PY  - 2023
SP  - 15
T2  - Nutrients
TI  - Effects of Probiotics on Autism Spectrum Disorder in Children: A Systematic Review and Meta-Analysis of Clinical Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36986145
UR  - https://mdpi-res.com/d_attachment/nutrients/nutrients-15-01415/article_deploy/nutrients-15-01415.pdf?version=1678870540
VL  - 15
ER  -
TY  - JOUR
AB  - OBJECTIVES: The present study aimed to meta-analytically estimate the dose-response relationship of atomoxetine for treating children with ADHD. 

METHODS: We systematically searched double-blind randomized placebo-controlled trials that evaluated the effectiveness of atomoxetine for treating ADHD in children. The search was carried out in PubMed, Cochrane Library, CINHAL, and ClinicalTrials.gov databases, covering articles from their inception until January 20, 2023. In addition, a dose-response meta-analysis was conducted.

RESULTS: In this dose-response meta-analysis, 12 double-blind randomized placebo-controlled trials involving 2,250 patients were included. The efficacy of atomoxetine increased up to a dosage of 1.4 mg/kg, after which it reached a plateau. 

CONCLUSIONS: The first dose-response meta-analysis of atomoxetine dosing for children with ADHD conducted here enhances the robustness of the Food and Drug Administration and the European Medicines Agency dose recommendations.
AN  - 38069471
AU  - Terao,
AU  - I.
AU  - Kodama,
AU  - W.
AU  - Tsuda,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/10870547231214988
L1  - internal-pdf://2099202423/terao-et-al-2023-the-dose-response-relationshi.pdf
PY  - 2023
SP  - 10870547231214988
T2  - Journal of Attention Disorders
TI  - The Dose-Response Relationship of Atomoxetine for the Treatment of Children With ADHD: A Systematic Review and Dose-Response Meta-Analysis of Double-Blind Randomized Placebo-Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38069471
UR  - https://journals.sagepub.com/doi/10.1177/10870547231214988
ER  -
TY  - JOUR
AB  - **Purpose**
This meta-analysis aims to evaluate the impact of Internet-based self-help interventions on the mental health of adolescents and college students. 

**Methods**
We conducted a systematic review of randomized controlled trials (RCTs) that investigated Internet-based self-help interventions aiming to mitigate mental health symptoms such as anxiety and depression, as well as managing high levels of stress, among adolescents and college students. Our search spanned databases including Web of Science, PubMed, Cochrane Library, and Embase, up until November 1st, 2022. It is essential to emphasize that our focus was the evaluation of symptoms (continuous outcomes), rather than the diagnosis of specific mental disorders. The meta-analysis was performed using the R version 4.3.1. The effect size measure was the standardized mean difference (SMD), and random-effects models were used to pool data from eligible RCTs. Subgroup analyses were carried out to examine variations in intervention effects based on factors such as sample type, intervention modality, guidance type, and intervention duration. 

**Results**
The meta-analysis was based on 25 comparisons involving a total of 4480 participants. In comparison to the control group (n = 2125), participants receiving interventions (n = 2355) reported significant reductions in symptoms of anxiety, depression, and stress, along with a significant improvement in quality of life. Specifically, for depression, we observed moderate intervention effects (SMD = -0.42, 95 % CI: -0.56, -0.27), and a similar pattern was seen for quality of life (SMD = 0.36, 95%CI: 0.22, 0.49). Small intervention effects were found for anxiety (SMD = -0.35, 95 % CI [-0.48, -0.22]) and stress (SMD = -0.35, 95 % CI [-0.51, -0.20]). Given significant heterogeneity, subgroup analyses were conducted for anxiety and depression, considering factors such as sample type, intervention method, and intervention duration. Notably, college students experienced more significant benefits in both anxiety and depression alleviation compared to adolescents. Longer interventions (&gt;8 weeks) were particularly effective in reducing anxiety and depression. Additionally, third-wave cognitive-behavioral therapy (CBT) showed pronounced intervention effects in both outcome measures, while the presence of guidance did not notably influence results. 

**Conclusion**
This meta-analysis underscores the positive impact of Internet-based self-help programs in alleviating the symptoms of psychological disorders among adolescents and college students. However, it is crucial to acknowledge that the available evidence exhibits inconsistencies and limitations. Therefore, further research utilizing rigorous methodologies is necessary to verify and broaden the findings of this meta-analysis.
AN  - 38023965
AU  - Wang,
AU  - Q.
AU  - Zhang,
AU  - W.
AU  - An,
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.invent.2023.100690
L1  - internal-pdf://3710722596/Wang-2023-A systematic review and meta-analysi.pdf
PY  - 2023
SP  - 100690
T2  - Internet Interventions
TI  - A systematic review and meta-analysis of Internet-based self-help interventions for mental health among adolescents and college students
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=38023965
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10654252/pdf/main.pdf
VL  - 34
ER  -
TY  - JOUR
AB  - **Background:** 
Previous studies have shown that physical activity interventions positively affect core symptoms and executive functioning in children with attention-deficit/hyperactivity disorder (ADHD). However, comparisons between different physical activity interventions still need to be made. This study is the first to analyze the effects of 10 different types of physical activity on children with ADHD through a network meta-analysis. 

**Methods:** 
PubMed, Embase, Web of Science, and Cochrane Library databases were searched for randomized controlled trials on the effects of physical activity interventions on children with ADHD. The search time frame was from database creation to October 2022. Two investigators independently performed literature screening, extraction, and quality assessment. Network meta-analysis was performed with Stata 15.1. 

**Results:** 
A total of 31 studies were included, and the results indicated that perceptual-motor training was the most effective in terms of motor ability and working memory (SUCRA = 82.7 and 73.3%, respectively). For attention problems and cognitive flexibility, aquatic exercise was the most effective (SUCRA = 80.9 and 86.6%, respectively). For social problems, horsemanship was the most effective (SUCRA = 79.4%). For inhibition switching, cognitive-motor training was the most effective (SUCRA = 83.5%). 

**Conclusion:** 
Our study revealed that aquatic exercise and perceptual-motor training had a superior overall performance. However, the effects of various physical activity interventions on different indicators in children with ADHD can vary depending on the individual and the intervention&#039;s validity. To ensure an appropriate physical activity intervention is selected, it is important to assess the severity of symptoms exhibited by children with ADHD beforehand. Copyright &copy; 2023 Li, Wang, Cui, Yan, Zang and Li.
AN  - 37021131
AU  - Li,
AU  - D.
AU  - Wang,
AU  - D.
AU  - Cui,
AU  - W.
AU  - Yan,
AU  - J.
AU  - Zang,
AU  - W.
AU  - Li,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fnins.2023.1139263
L1  - internal-pdf://3253611460/Li-2023-Effects of different physical activity.pdf
PY  - 2023
SP  - 1139263
T2  - Frontiers in Neuroscience
TI  - Effects of different physical activity interventions on children with attention-deficit/hyperactivity disorder: A network meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37021131
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067581/pdf/fnins-17-1139263.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - **Objective**
To comprehensively evaluate the efficacy of non-invasive brain stimulation (NIBS) in patients with autism spectrum disorder (ASD) in randomized controlled trials (RCT), providing a reference for future research on the same topic. 

**Methods**
Five databases were searched (Pubmed, Web of Science, Medline, Embase, and Cochrane library) and tracked relevant references, Meta-analysis was performed using RevMan 5.3 software. 

**Results**
Twenty-two references (829 participants) were included. The results of the meta-analysis showed that NIBS had positive effects on repetitive and stereotypical behaviors, cognitive function, and executive function in autistic patients. Most of the included studies had a moderate to high risk of bias, Mainly because of the lack of blinding of subjects and assessors to treatment assignment, as well as the lack of continuous observation of treatment effects. 

**Conclusion**
Available evidence supports an improvement in some aspects of NIBS in patients with ASD. However, due to the quality of the original studies and significant publication bias, this evidence must be treated with caution. Further large multicenter randomized double-blind controlled trials and appropriate follow-up observations are needed to further evaluate the specific efficacy of NIBS in patients with ASD.
AN  - WOS:001024195900001
AU  - Liu,
AU  - A.
AU  - N.
AU  - Gong,
AU  - C.
AU  - Wang,
AU  - B.
AU  - B.
AU  - Sun,
AU  - J.
AU  - X.
AU  - Jiang,
AU  - Z.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3389/fpsyt.2023.1147327
L1  - internal-pdf://0811177882/Liu_2023.pdf
PY  - 2023
SP  - 18
T2  - Frontiers in Psychiatry
TI  - Non-invasive brain stimulation for patient with autism: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001024195900001
VL  - 14
ER  -
TY  - JOUR
AB  - **Objective:** 
Internet-based cognitive behavior therapy (ICBT) may provide an accessible alternative to face-to-face treatment, but the evidence base in adolescents is limited. This systematic review and meta-analysis aims to comprehensively assess the efficacy of ICBT in addressing depression among adolescents.

**Methods:** 
Four electronic databases were searched on June 8, 2023. Randomized controlled trials (RCTs) evaluating the efficacy of ICBT for depression in adolescents were included. The quality of the studies was assessed using the risk of bias tool recommended by the Cochrane Handbook. Furthermore, the GRADE approach was employed to gauge the certainty of the obtained evidence. Meta-analysis was conducted using RevMan 5.4, and Egger&#039;s test was implemented through Stata for assessment of potential publication bias.

**Results:** 
A total of 18 RCTs involving 1683 patients were included. In comparison to control groups like attention control, waiting list, and treatment as usual, our meta-analysis findings elucidate a significant reduction in depression scores (SMD = -0.42, 95 % CI: [-0.74, -0.11], p &lt; .05) as well as anxiety scores (SMD = -0.34, 95 % CI: [-0.60, -0.08], p &lt; .05) in adolescents following ICBT interventions. Furthermore, the analysis indicated no notable distinctions in patient&#039;s quality of life (QoL) scores. (SMD = 0.12, 95 % CI: [-0.10, 0.34], p &gt; .05).

**Conclusion:** 
Results provide evidence of the efficacy of ICBT to reduce depressive and anxiety symptoms in adolescents. These research findings are of vital significance for the establishment of evidence-based treatment guidelines in the digital era.Trial registration: PROSPERO registration: CRD42021277562.
AD  - Wu, Yanan. Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China.Wu, Yanan. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.Wu, Yanan. Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China.Fenfen, E. Qinghai university affiliated hospital.Wang, Yan. Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China.Wang, Yan. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.Wang, Yan. Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China.Xu, Meng. Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China.Xu, Meng. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.Xu, Meng. Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China.Liu, Simin. Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China.Zhou, Liying. Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China.Zhou, Liying. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.Zhou, Liying. Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China.Song, Guihang. Healthcare Security Administration of Gansu Province, Lanzhou 730000, China.Shang, Xue. School of Public Health and Emergency Management, Southern University of Science and Technology.Yang, Chaoqun. Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China.Yang, Chaoqun. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.Yang, Chaoqun. Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China.Yang, Kehu. Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China.Yang, Kehu. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.Yang, Kehu. Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China.Li, Xiuxia. Health Technology Assessment Center/Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China.Li, Xiuxia. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.Li, Xiuxia. Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China.
AN  - 37822787
AU  - Wu,
AU  - Y.
AU  - Fenfen,
AU  - E.
AU  - Wang,
AU  - Y.
AU  - Xu,
AU  - M.
AU  - Liu,
AU  - S.
AU  - Zhou,
AU  - L.
AU  - Song,
AU  - G.
AU  - Shang,
AU  - X.
AU  - Yang,
AU  - C.
AU  - Yang,
AU  - K.
AU  - Li,
AU  - X.
DA  - Dec
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.invent.2023.100673
DP  - Ovid Technologies
J2  - Internet Interv
L1  - internal-pdf://0780078628/Wu-2023-Efficacy of internet-based cognitive-b.pdf
LA  - English
M3  - Review
N1  - Wu, YananFenfen, EWang, YanXu, MengLiu, SiminZhou, LiyingSong, GuihangShang, XueYang, ChaoqunYang, KehuLi, Xiuxia
PY  - 2023
SP  - 100673
T2  - Internet Interventions
TI  - Efficacy of internet-based cognitive-behavioral therapy for depression in adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37822787
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37822787&amp;id=doi:10.1016%2Fj.invent.2023.100673&amp;issn=2214-7829&amp;isbn=&amp;volume=34&amp;issue=&amp;spage=100673&amp;pages=100673&amp;date=2023&amp;title=Internet+Interventions&amp;atitle=Efficacy+of+internet-based+cognitive-behavioral+therapy+for+depression+in+adolescents%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Wu&amp;pid=%3Cauthor%3EWu+Y%3C%2Fauthor%3E%3CAN%3E37822787%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10562795/pdf/main.pdf
VL  - 34
ER  -
TY  - JOUR
AB  - BACKGROUND: Parenting interventions offer opportunities for reducing emotional problems in children and adolescents, based on addressing parental risk and protective factors. Online parenting interventions were developed more recently to increase access to interventions for parents, and the aim of this systematic review and meta-analysis is to investigate their efficacy. 

METHODS: We conducted a meta-analysis pooling studies that tested online parenting interventions having as outcome emotional problems in children/adolescents. We considered as secondary outcome parent mental health and moderation effects for the type of population, intervention characteristics, and risk of bias. 

RESULTS: Thirty-one studies met the inclusion criteria and were included in the meta-analysis. For child/adolescent emotional problems, at post-intervention, 13 studies were pooled, yielding an ES of g = -0.26 (95% CI [-0.41, -0.11]; p &lt; .001) favoring the online parental interventions over wait-list, while at follow-up five RCTs were pooled, yielding an ES of g = -0.14 (95% CI [-0.25, -0.02]; p = .015) favoring the parental online interventions over wait-list. Moderation analyses suggest that longer online parenting programs are more effective in improving child emotional problems. 

CONCLUSIONS: Online parent programs have positive effects on reducing emotional symptoms in children and adolescents. Future research will need to develop and investigate the efficacy of the programs that can personalize their contents and delivery methods.
AN  - 36860086
AU  - David,
AU  - O.
AU  - A.
AU  - Fodor,
AU  - L.
AU  - A.
AU  - Dascal,
AU  - M.
AU  - D.
AU  - Miron,
AU  - I.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/00207640231156034
L1  - internal-pdf://3501365321/David.pdf
PY  - 2023
SP  - 207640231156034
T2  - International Journal of Social Psychiatry
TI  - The efficacy of online parenting interventions in addressing emotional problems in children and adolescents: A meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36860086
ER  -
TY  - JOUR
AB  - **BACKGROUND**
The prescription of antidepressant drugs during pregnancy has been steadily increasing for several decades. Meta-analyses (MAs), which increase the statistical power and precision of results, have gained interest for assessing the safety of antidepressant drugs during pregnancy. OBJECTIVE: We aimed to provide a meta-review of MAs assessing the benefits and risks of antidepressant drug use during pregnancy. 

**METHODS**
Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, a literature search on PubMed and Web of Science databases was conducted on 25 October, 2021, on MAs assessing the association between antidepressant drug use during pregnancy and health outcomes for the pregnant women, embryo, fetus, newborn, and developing child. Study selection and data extraction were carried out independently and in duplicate by two authors. The methodological quality of included studies was evaluated with the AMSTAR-2 tool. Overlap among MAs was assessed by calculating the corrected covered area. Data were presented in a narrative synthesis, using four levels of evidence. 

**RESULTS**
Fifty-one MAs were included, all but one assessing risks. These provided evidence for a significant increase in the risks for major congenital malformations (selective serotonin reuptake inhibitors, paroxetine, fluoxetine, no evidence for sertraline; eight MAs), congenital heart defects (paroxetine, fluoxetine, sertraline; 11 MAs), preterm birth (eight MAs), neonatal adaptation symptoms (eight MAs), and persistent pulmonary hypertension of the newborn (three MAs). There was limited evidence (only one MA for each outcome) for a significant increase in the risks for postpartum hemorrhage, and with a high risk of bias, for stillbirth, impaired motor development, and intellectual disability. There was inconclusive evidence, i.e., discrepant results, for an increase in the risks for spontaneous abortion, small for gestational age and low birthweight, respiratory distress, convulsions, feeding problems, and for a subsequent risk for autism with an early antidepressant drug exposure. Finally, MAs provided no evidence for an increase in the risks for gestational hypertension, preeclampsia, and for a subsequent risk for attention-deficit/hyperactivity disorder. Only one MA assessed benefits, providing limited evidence for preventing relapse in severe or recurrent depression. Effect sizes were small, except for neonatal symptoms (small to large). Results were based on MAs in which overall methodological quality was low (AMSTAR-2 score = 54.8% +/- 12.9%, [19-81%]), with a high risk of bias, notably indication bias. The corrected covered area was 3.27%, which corresponds to a slight overlap. 

**CONCLUSIONS**
This meta-review has implications for clinical practice and future research. First, these results suggest that antidepressant drugs should be used as a second-line treatment during pregnancy (after first-line psychotherapy, according to the guidelines). The risk of major congenital malformations could be prevented by observing guidelines that discourage the use of paroxetine and fluoxetine. Second, to decrease heterogeneity and bias, future MAs should adjust for maternal psychiatric disorders and antidepressant drug dosage, and perform analyses by timing of exposure.
AN  - 36853497
AU  - Desaunay,
AU  - P.
AU  - Eude,
AU  - L.
AU  - G.
AU  - Dreyfus,
AU  - M.
AU  - Alexandre,
AU  - C.
AU  - Fedrizzi,
AU  - S.
AU  - Alexandre,
AU  - J.
AU  - Uguz,
AU  - F.
AU  - Guenole,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40272-023-00561-2
L1  - internal-pdf://1877128694/Desauney_2+23.pdf
PY  - 2023
SP  - 28
T2  - Paediatric Drugs
TI  - Benefits and Risks of Antidepressant Drugs During Pregnancy: A Systematic Review of Meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36853497
UR  - https://link.springer.com/article/10.1007/s40272-023-00561-2
VL  - 28
ER  -
TY  - JOUR
AB  - BACKGROUND: Educational interventions are a key element in the care of young patients with feeding and eating disorders, forming part of the majority of therapeutic approaches. The aim of this review is to evaluate the impact of educational interventions in adolescents with feeding and eating disorders. 

METHODS: Following the PRISMA recommendations electronic databases were searched up to 29 June 2023. Studies related to educational interventions in young population diagnosed with feeding and eating disorders (anorexia nervosa, avoidant/restrictive food intake disorder, bulimia nervosa, pica and ruminative disorders and binge- eating disorder) in Spanish and English language, without temporal limitation, were located in the databases: PubMed, Scopus, CINAHL, Cochrane Library, PsycINFO, CUIDEN, DIALNET, and ENFISPO. A search in the databases of grey literature was performed in OpenGrey and Teseo. The review protocol was registered in PROSPERO (CRD42020167736). 

RESULTS: A total of 191 articles were selected from the 9744 citations screened. Ten publications were included. The results indicated variability between educational programs, including individual and group interventions, learning techniques and various research methodologies. Variables such as learning, attitudinal and perceptual changes, anthropometric parameters, symptom improvement, normalization of eating patterns, evaluation of the program and cognitive flexibility were identified. The risk of bias was high due to the low methodological quality of a large number of studies analyzed. 

CONCLUSION: The results indicate that educational interventions can influence the improvement of knowledge level and have a positive effect on health outcomes. Although education is a common practice in the treatment of these pathologies, high-quality studies were not identified. Thus, this review concludes that additional evidence is needed to evaluate the effectiveness of educational programs, with further research studies, especially randomized controlled trials, to confirm these results.
AN  - 37608142
AU  - Ladron-Arana,
AU  - S.
AU  - Orzanco-Garralda,
AU  - R.
AU  - Escalada-Hernandez,
AU  - P.
AU  - Aguilera-Serrano,
AU  - C.
AU  - Gutierrez-Valencia,
AU  - M.
AU  - Urbiola-Castillo,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40519-023-01594-9
L1  - internal-pdf://3564998008/Ladron-Arana-2023-Efficacy of educational inte.pdf
PY  - 2023
SP  - 69
T2  - Eating &amp; Weight Disorders: EWD
TI  - Efficacy of educational interventions in adolescent population with feeding and eating disorders: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37608142
UR  - https://link.springer.com/content/pdf/10.1007/s40519-023-01594-9.pdf
VL  - 28
ER  -
TY  - JOUR
AB  - Folic acid, a water-soluble vitamin B nutrient, plays an important role not only in maintaining a healthy pregnancy but also in offspring brain development and function, however, it remains unclear whether maternal folic acid (FA) supplementation associated with the risk of different postnatal neurodevelopmental outcomes. 

Here, we performed a systematic review and meta-analysis on the impact of maternal FA supplementation on a wide range of postnatal neurodevelopmental outcomes which include intellectual development, risk of autistic traits, ADHD, behavior, language, and psychomotor problems, using studies extracted from the following databases, including MEDLINE, Web of Science, Cochrane Library, Scopus, EMBASE, and PsychInfo. 

Thirty-two cohort studies and seven case-control studies were included in this meta-analysis. In the present study, we found that prenatal FA supplementation had a positive impact on offspring&#039;s neurodevelopmental outcomes, including improved intellectual development and reduced risk of autism traits, ADHD, behavioral, and language problems. We also found that FA over-supplementation was not associated with an improvement in offspring&#039;s brain development, and may have a negative impact on offspring&#039;s neurodevelopmental outcomes. This study proved the first panoramic review on the relationship of FA supplementation with offspring&#039;s neurodevelopment. Further studies focusing on different dosages and periods of FA supplementation are needed.Supplemental data for this article is available online at https://doi.org/10.1080/10408398.2021.1993781 .
AN  - 34672229
AU  - Chen,
AU  - H.
AU  - Qin,
AU  - L.
AU  - Gao,
AU  - R.
AU  - Jin,
AU  - X.
AU  - Cheng,
AU  - K.
AU  - Zhang,
AU  - S.
AU  - Hu,
AU  - X.
AU  - Xu,
AU  - W.
AU  - Wang,
AU  - H.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/10408398.2021.1993781
L1  - internal-pdf://0854855524/Chen_2023.pdf
PY  - 2023
SP  - 3771-3787
T2  - Critical Reviews in Food Science &amp; Nutrition
TI  - Neurodevelopmental effects of maternal folic acid supplementation: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34672229
VL  - 63
ER  -
TY  - JOUR
AB  - **Background**

Brexpiprazole is the newest antipsychotic drug approved as an adjunctive for treatment‐resistant depression. This systematic review provides comprehensive, high‐quality evidence for the effects of brexpiprazole in major depressive disorder (MDD) based on existing and emerging randomised controlled trials (RCTs).

**Objectives**

To evaluate the benefits and harms of brexpiprazole as monotherapy or adjunct treatment in the acute and longer‐term treatment of MDD compared to placebo or other antidepressive agents.

**Search methods**

We used standard, extensive Cochrane search methods. The latest search date was November 2021.

**Selection criteria**

We included RCTs in people with a history of non‐response to one or more antidepressant monotherapies comparing brexpiprazole as monotherapy or adjunct treatment with placebo or other antidepressive agents.

**Data collection and analysis**

We used standard Cochrane methods. Primary outcomes were 1. response to treatment, measured as number of participants who achieved 50% or more reduction of the score on a validated scale for depression, 2. dropouts due to any reason, and 3. dropouts due to adverse effects, all measured at eight weeks (acute treatment). Our secondary outcomes were 4. number of participants who responded to treatment after two and 18 weeks, number of participants who achieved remission after eight weeks, 5. total number of participants with any adverse events, 6. social functioning or adjustment, and 7. health‐related quality of life. We used GRADE to assess certainty of evidence for each outcome.Main resultsWe retrieved nine studies with 3424 participants with treatment‐resistant depression, defined as lack of response to at least two trials of antidepressant monotherapy. The age of participants was 18 to 65 years in seven studies, 18 to 75 years in one study, and older than 65 years in one study. Inclusion criteria for all studies required a diagnosis of MDD with a current major depressive episode per Diagnostic and Statistical Manual of Mental Disorders Text Revision Fourth Edition criteria and additional criteria on minimal scores on Montgomery&ndash;Åsberg Depression Rating Scale (MADRS) and Hamilton Depression Rating Scale which varied across studies. Eight studies compared brexpiprazole as adjunctive treatment to an antidepressant versus placebo as adjunctive treatment to an antidepressant. One study added brexpiprazole or placebo to a combination of antidepressant and ketamine. Four studies used fixed dosages and five studies used flexible dosages of brexpiprazole. The manufacturer sponsored eight studies and one study was independently funded.Brexpiprazole was superior in achieving response at eight weeks (odds ratio (OR) 1.47, 95% confidence interval (CI) 1.23 to 1.75; 8 studies, 3409 participants; high‐certainty evidence). More participants randomised to brexpiprazole dropped out due to any cause at eight weeks (OR 1.37, 95% CI 1.02 to 1.83; 7 studies, 2523 participants; high‐certainty evidence) or due to adverse effects (OR 2.88, 95% CI 1.37 to 6.05; 6 studies, 2472 participants; high‐certainty evidence). Brexpiprazole was superior to placebo when added to an antidepressant for achieving remission at eight weeks (OR 1.46, 95% CI 1.19 to 1.79; 7 studies, 3358 participants; high‐certainty evidence). When response was defined based on a change in the score on MADRS, brexpiprazole also demonstrated better efficacy than placebo (mean difference (MD) &ndash;1.39, 95% CI &ndash;1.96 to &ndash;0.82; 8 studies, 3263 participants; high‐certainty evidence). Compared to placebo, add‐on brexpiprazole is probably more likely to result in akathisia (OR 2.95, 95% CI 2.06 to 4.21; 7 studies, 3358 participants; moderate‐certainty evidence) and weight gain (OR 3.14, 95% CI 2.19 to 4.49; 9 studies, 3424 participants; moderate‐certainty evidence).The risk of bias varied between low and unclear for most studies. Only one study was at high risk of selective reporting bias and other bias; however, this study had a small sample size and its impact on overall risk of bias was not considered significant. The certainty of the evidence on five of the main outcomes (response to treatment, measured as number of participants who achieved response and change in depressive symptoms, remission, dropouts due to any cause, dropouts due to adverse effects) was high. The certainty of evidence for akathisia and weight gain was downgraded one level to moderate due to indirectness.

**Authors&#039; conclusions**

Our review supports the superior efficacy of add‐on brexpiprazole in comparison to placebo in adults with treatment‐resistant depression for the short‐term and acute treatment of depression. Our findings were limited by the small number of studies and the moderate‐certainty evidence for the most common adverse effects (akathisia and weight gain). There was insufficient evidence for the effects of brexpiprazole for depression in older people or children. In addition, we found no studies that compared brexpiprazole to other antidepressants or where brexpiprazole was added after lack of response to only one antidepressant. We also lacked sufficient data to establish the long‐term efficacy of brexpiprazole as adjunctive treatment. Active comparators, long‐term studies in different age groups and cost‐effect analyses are needed to more precisely establish the clinical role of brexpiprazole in the treatment of MDD.
AU  - Ralovska,
AU  - S.
AU  - Koychev,
AU  - I.
AU  - Marinov,
AU  - P.
AU  - Furukawa,
AU  - T.
AU  - A.
AU  - Mulsant,
AU  - B.
AU  - Cipriani,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD013866.pub2
L1  - internal-pdf://2237540771/Ralovska_et_al-2023-Cochrane_Database_of_Syste.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Brexpiprazole versus placebo or other antidepressive agents for treating depression
ER  -
TY  - JOUR
AB  - **Background:** 
Forced displacement is associated with elevated risk for poor psychosocial wellbeing, yet there remains a lack of clarity around the effectiveness of commonly implemented psychosocial support interventions focused on preventing disorder and promoting wellbeing. This study aimed to synthesize the literature on evaluations of psychosocial support interventions for populations affected by forced displacement. 

**Methods:** 
We searched for peer reviewed and gray literature in seven databases (PubMed, Embase, Global Health, CINAHL, SocIndex, PsychInfo, PILOTS), fifteen organizational websites, and via solicitation through multiple networks. Various study designs were included, with the criteria that they report an evaluation of a psychosocial intervention delivered to populations affected by forced displacement, and included quantitative or qualitative data on psychosocial outcomes. Records were screened independently by two reviewers at both title/abstract and full-text review; data was double-extracted and study quality assessed, with discrepancies resolved by consensus. Meta-analyses for seven outcomes were conducted on a subset of 33 studies. 

**Results:** 
We identified 162 reports. Over half (55%) used a single-group study design, with fewer using non-random (19%) or randomized (21%) comparisons. Study designs incorporating comparison conditions were less likely to report positive findings than single-group studies. In the meta-analyses, a moderately strong overall effect was found for psychosocial wellbeing (ES: -0.534, 95% CI: [-0.870, -0.197], p=.005); small effects on both internalizing (ES: -0.152, 95% CI: [-0.310, 0.005], p= .057) and externalizing (ES: -0.249, 95% CI: [-0.515, 0.016], p=.064) problems were promising but not conclusive. Subgroup analysis suggested differential impacts on internalizing problems for adults (improvement; ES: -0.289, 95% CI: [-0.435, -0.143], p=.001) and children (worsening; ES: 0.129, 95% CI: [.054, 0.204], p=.002). Other subgroup analyses showed little meaningful variation by context, population, or intervention characteristics. 

**Conclusion:** 
Pragmatic, field-driven program evaluations are dominated by single-group designs with significant risk of bias. Findings from controlled studies are promising but highlight a need for more rigorous research to support causal inference, align outcomes with theories of change, improve measurement of more positive or wellbeing-focused outcomes, examine subgroup differences, and report potentially negative impacts.
AN  - 36816445
AU  - Nguyen,
AU  - A.
AU  - J.
AU  - Lasater,
AU  - M.
AU  - E.
AU  - Lee,
AU  - C.
AU  - Mallawaarachchi,
AU  - I.
AU  - V.
AU  - Joshua,
AU  - K.
AU  - Bassett,
AU  - L.
AU  - Gelsdorf,
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jmh.2023.100168
L1  - internal-pdf://3743352951/1-s2.0-S2666623523000181-main.cleaned.pdf
PY  - 2023
SP  - 100168
T2  - Journal of Migration and Health
TI  - Psychosocial support interventions in the context of forced displacement: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36816445
VL  - 7
ER  -
TY  - JOUR
AB  - **ABSTRACT**

Experiences in the first years of life can shape a range of outcomes throughout the lifespan. Effective early interventions have the potential to offset negative outcomes associated with early adversity. A broad range of psychodynamic interventions are available to children under five and their caregivers but there is a lack of research synthesizing the current evidence for their effectiveness.

This paper presents a systematic review and meta-analysis of the evidence for the effectiveness of psychodynamic interventions for children under 5 years of age and their caregivers. Following a systematic search of 10 databases and screening for eligibility, 77 papers were included in the review.

Most studies reported positive outcomes on a range of parent and infant domains. The meta-analyses of controlled studies found significant effects of psychodynamic interventions compared to control conditions on parental reflective functioning, maternal depression, infant behavior, and infant attachment. No significant differences between psychodynamic and control interventions were found for parental stress, and parent-infant interactions. Very few studies were rated as good quality and further high-quality research is needed. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-87220-001
AU  - Sleed,
AU  - M.
AU  - Li,
AU  - E.
AU  - T.
AU  - Vainieri,
AU  - I.
AU  - Midgley,
AU  - N.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/15289168.2023.2223739
L1  - internal-pdf://1816866093/Sleed-2023-The evidence-base for psychodynamic.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Journal of Infant, Child &amp; Adolescent Psychotherapy
TI  - The evidence-base for psychodynamic interventions with children under 5 years of age and their caregivers: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-87220-001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/15289168.2023.2223739
ER  -
TY  - JOUR
AB  - **Purpose of Review**
Problematic mobile phone use (PMPU) has become a public health issue. This study sought to investigate the effects of psychological interventions (PI) or exercise interventions (EI) for PMPU through a systematic review and meta-analysis. A literature search of ten databases was executed from January 2001 to August 2022. A total of 26 eligible RCTs (31 pairwise comparisons) were finally included. Posttreatment means and SDs were compared between intervention and control groups, and pooled effect sizes were calculated. This study is registered on PROSPERO, number CRD42022296418.

**Recent findings**
A meta-analysis of 31 pairwise comparisons showed that interventions significantly reduced the total PMPU scores (SMD = - 1.00), with significant heterogeneity (I-2 = 72.8%). Twenty-three of these trials reported PI (SMD = - 0.99) and the other eight reported EI (SMD = - 1.02); the change in total PMPU scores was not significantly different between PI and EI (P = 0.787). Among them, the largest effect sizes were found for mindfulness therapy (MT), cognitive behavioral therapy (CBT), and general aerobic exercise (GAE) (MT: SMD = - 1.50; CBT: SMD = - 1.37; GAE: SMD = - 1.32). In addition, interventions also reduced the MPUT (SMD = - 0.91), anxiety (SMD = - 1.63), loneliness (SMD = - 1.10), stress (SMD = - 0.59), and depression (SMD = - 0.31), and increased mindful attention (SMD = 1.07) and inadequacy (SMD = 1.12).

**Summary**
This is the first meta-analysis on PI or EI for PMPU. The results showed that PI or EI was equally effective in reducing PMPU. However, more rigorous trials are needed to explore intervention criteria.
AN  - WOS:000969796900001
AU  - Zhang,
AU  - K.
AU  - X.
AU  - Lu,
AU  - X.
AU  - Y.
AU  - Zhang,
AU  - X.
AU  - Q.
AU  - Zhang,
AU  - J.
AU  - H.
AU  - Ren,
AU  - J.
AU  - Guo,
AU  - H.
AU  - Y.
AU  - Zhu,
AU  - Z.
AU  - H.
AU  - Yang,
AU  - H.
AU  - Y.
AU  - Yuan,
AU  - G.
AU  - J.
AU  - Jin,
AU  - G.
AU  - F.
AU  - Du,
AU  - J.
AU  - Shi,
AU  - H.
AU  - Y.
AU  - Hao,
AU  - J.
AU  - H.
AU  - Sun,
AU  - Y.
AU  - Su,
AU  - P.
AU  - Y.
AU  - Yang,
AU  - L.
AU  - S.
AU  - Zhang,
AU  - Z.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40429-023-00471-w
L1  - internal-pdf://1731558137/Zhang-2023-Effects of Psychological or Exercis.pdf
PY  - 2023
SP  - 24
T2  - Current Addiction Reports
TI  - Effects of Psychological or Exercise Interventions on Problematic Mobile Phone Use: a Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000969796900001
UR  - https://link.springer.com/article/10.1007/s40429-023-00471-w
UR  - https://link.springer.com/content/pdf/10.1007/s40429-023-00471-w.pdf
ER  -
TY  - JOUR
AB  - **Background:**

Melatonin has become a widely used sleeping aid for young individuals currently not included in existing guidelines. The aim was to develop a recommendation on the use of melatonin in children and adolescents aged 2-20 years, with chronic insomnia due to disorders beyond indication. 

**Methods:**

We performed a systematic search for guidelines, systematic reviews, and randomised trials (RCTs) in Medline, Embase, Cochrane Library, PsycInfo, Cinahl, Guidelines International Network, Trip Database, Canadian Agency for Drugs and Technologies in Health, American Academy of Sleep Medicine, European Sleep Research Society and Scandinavian Health Authorities databases. A separate search for adverse events was also performed. The latest search for guidelines, systematic reviews, and adverse events was performed on March 17, 2023. The latest search for RCTs was performed on to February 6, 2023. The language was restricted to English, Danish, Norwegian, and Swedish. Eligible participants were children and adolescents (2-20 years of age) with chronic insomnia due to underlying disorders, in whom sleep hygiene practices have been inadequate and melatonin was tested. Studies exclusively on autism spectrum disorders or attention deficit hyperactive disorder were excluded. There were no restrictions on dosage, duration of treatment, time of consumption or release formula. Primary outcomes were quality of sleep, daytime functioning and serious adverse events, assessed at 2-4 weeks post-treatment. Secondary outcomes included total sleep time, sleep latency, awakenings, drowsiness, quality of life, non-serious adverse events, and all-cause dropouts (assessed at 2-4 weeks post-treatment), plus quality of sleep and daytime functioning (assessed at 3-6 months post-treatment). Pooled estimates were calculated using inverse variance random effects model. Statistical heterogeneity was calculated using I&lt;sup&gt;2&lt;/sup&gt; statistics. Risk of bias was assessed using Cochrane risk of bias tool. Publication bias was assessed using funnel plots. A multidisciplinary guideline panel constructed the recommendation using Grades of Recommendation, Assessment, Development and Evaluation (GRADE). The certainty of evidence was considered either high, moderate, low or very low depending on the extent of risk of bias, inconsistency, imprecision, indirectness, or publication bias. The evidence-to-decision framework was used to discuss the feasibility and acceptance of the constructed recommendation and its impact on resources and equity. The protocol is registered with the Danish Health Authority. 

**Findings:**

We identified 13 RCTs, including 403 patients with a wide range of conditions. Melatonin reduced sleep latency by 14.88 min (95% CI 23.42-6.34, 9 studies, I&lt;sup&gt;2&lt;/sup&gt; = 60%) and increased total sleep time by 18.97 min (95% CI 0.37-37.57, 10 studies, I&lt;sup&gt;2&lt;/sup&gt; = 57%). The funnel plot for total sleep time showed no apparent indication of publication bias. No other clinical benefits were found. The number of patients experiencing adverse events was not statistically increased however, safety data was scarce. Certainty of evidence was low. 

**Interpretation:**

Low certainty evidence supports a moderate effect of melatonin in treating sleep continuity parameters in children and adolescents with chronic insomnia due to primarily medical disorders beyond indication. The off-label use of melatonin for these patients should never be the first choice of treatment, but may be considered by medical specialists with knowledge of the underlying disorder and if non-pharmacological interventions are inadequate. If treatment with melatonin is initiated, adequate follow-up to evaluate treatment effect and adverse events is essential. Funding: The Danish Health Authority. The Parker Institute, Bispebjerg and Frederiksberg Hospital, supported by the Oak Foundation.
AN  - 37457114
AU  - Edemann-Callesen,
AU  - H.
AU  - Andersen,
AU  - H.
AU  - K.
AU  - Ussing,
AU  - A.
AU  - Virring,
AU  - A.
AU  - Jennum,
AU  - P.
AU  - Debes,
AU  - N.
AU  - M.
AU  - Laursen,
AU  - T.
AU  - Baandrup,
AU  - L.
AU  - Gade,
AU  - C.
AU  - Dettmann,
AU  - J.
AU  - Holm,
AU  - J.
AU  - Krogh,
AU  - C.
AU  - Birkefoss,
AU  - K.
AU  - Tarp,
AU  - S.
AU  - Handel,
AU  - M.
AU  - N.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.eclinm.2023.102049
L1  - internal-pdf://0943592080/Edemann-Callese-2023-Use of melatonin for chil.pdf
PY  - 2023
SP  - 102049
T2  - EClinicalMedicine
TI  - Use of melatonin for children and adolescents with chronic insomnia attributable to disorders beyond indication: a systematic review, meta-analysis and clinical recommendation
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37457114
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339185/pdf/main.pdf
VL  - 61
ER  -
TY  - JOUR
AB  - **Background**
Many infants are fed infant formulas to promote growth. Some formulas have a high protein content (&ge; 2.5 g per 100 kcal) to accelerate weight gain during the first year of life. The risk‐benefit balance of these formulas is unclear.

**Objectives**
To evaluate the benefits and harms of higher protein intake versus lower protein intake in healthy, formula‐fed term infants.

**Search methods**
We searched CENTRAL, MEDLINE, Embase, CINAHL, LILACS, OpenGrey, clinical trial registries, and conference proceedings in October 2022.

**Selection criteria**
We included randomized controlled trials (RCTs) of healthy formula‐fed infants (those fed only formula and those given formula as a complementary food). We included infants of any sex or ethnicity who were fed infant formula for at least three consecutive months at any time from birth. We excluded quasi‐randomized trials, observational studies, and infants with congenital malformations or serious underlying diseases. We defined high protein content as 2.5 g or more per 100 kcal, and low protein content as less than 1.8 g per 100 kcal (for exclusive formula feeding) or less than 1.7 g per 100 kcal (for complementary formula feeding).

**Data collection and analysis**
Four review authors independently assessed the risk of bias and extracted data from trials, and a fifth review author resolved discrepancies. We performed random‐effects meta‐analyses, calculating risk ratios (RRs) or Peto odds ratios (Peto ORs) with 95% confidence intervals (CIs) for dichotomous outcomes, and mean differences (MDs) with 95% CIs for continuous outcomes. We used the GRADE approach to evaluate the certainty of the evidence.

**Main results**
We included 11 RCTs (1185 infants) conducted in high‐income countries. Seven trials (1629 infants) compared high‐protein formula against standard‐protein formula, and four trials (256 infants) compared standard‐protein formula against low‐protein formula. The longest follow‐up was 11 years.

High‐protein formula versus standard‐protein formula

We found very low‐certainty evidence that feeding healthy term infants high‐protein formula compared to standard‐protein formula has little or no effect on underweight (MD in weight‐for‐age z‐score 0.05 SDs, 95% CI &minus;0.09 to 0.19; P = 0.51, I2 = 61%; 7 studies, 1629 participants), stunting (MD in height‐for‐age z‐score 0.15 SDs, 95% CI &minus;0.05 to 0.35; P = 0.14, I2 = 73%; 7 studies, 1629 participants), and wasting (MD in weight‐for‐height z‐score &minus;0.12 SDs, 95% CI &minus;0.31 to 0.07; P = 0.20, I2 = 94%; 7 studies, 1629 participants) in the first year of life.

We found very low‐certainty evidence that feeding healthy infants high‐protein formula compared to standard‐protein formula has little or no effect on the occurrence of overweight (RR 1.26, 95% CI 0.63 to 2.51; P = 0.51; 1 study, 1090 participants) or obesity (RR 1.96, 95% CI 0.59 to 6.48; P = 0.27; 1 study, 1090 participants) at five years of follow‐up.

No studies reported all‐cause mortality.

Feeding healthy infants high‐protein formula compared to standard‐protein formula may have little or no effect on the occurrence of adverse events such as diarrhea, vomiting, or milk hypersensitivity (RR 0.93, 95% CI 0.76 to 1.13; P = 0.44, I2 = 0%; 4 studies, 445 participants; low‐certainty evidence) in the first year of life.

Standard‐protein formula versus low‐protein formula

We found very low‐certainty evidence that feeding healthy infants standard‐protein formula compared to low‐protein formula has little or no effect on underweight (MD in weight‐for‐age z‐score 0.0, 95% CI &minus;0.43 to 0.43; P = 0.99, I2 = 81%; 4 studies, 256 participants), stunting (MD in height‐for‐age z‐score &minus;0.01, 95% CI &minus;0.36 to 0.35; P = 0.96, I2 = 73%; 4 studies, 256 participants), and wasting (MD in weight‐for‐height z‐score 0.13, 95% CI &minus;0.29 to 0.56; P = 0.54, I2 = 95%; 4 studies, 256 participants) in the first year of life.

No studies reported overweight, obesity, or all‐cause mortality.

Feeding healthy infants standard‐protein formula compared to low‐protein formula may have little or no effect on the occurrence of adverse events such as diarrhea, vomiting, or milk hypersensitivity (Peto OR 1.55, 95% CI 0.70 to 3.40; P = 0.28, I2 = 0%; 2 studies, 206 participants; low‐certainty evidence) in the first four months of life.

**Authors&#039; conclusions**
We are unsure if feeding healthy infants high‐protein formula compared to standard‐protein formula has an effect on undernutrition, overweight, or obesity. There may be little or no difference in the risk of adverse effects between infants fed with high‐protein formula versus those fed with standard‐protein formula.

We are unsure if feeding healthy infants standard‐protein formula compared to low‐protein formula has any effect on undernutrition. There may be little or no difference in the risk of adverse effects between infants fed with standard‐protein formula versus those fed with low‐protein formula.

The findings of six ongoing studies and two studies awaiting classification studies may change the conclusions of this review.
AU  - Gonzalez-Garay,
AU  - A.
AU  - G.
AU  - Serralde-Z&uacute;&ntilde;iga,
AU  - A.
AU  - E.
AU  - Medina
AU  - Vera,
AU  - I.
AU  - Velasco
AU  - Hidalgo,
AU  - L.
AU  - Alonso
AU  - Oca&ntilde;a,
AU  - M.
AU  - V.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD013758.pub2
L1  - internal-pdf://3119323638/Gonzalez-Garay_et_al-2023-Cochrane_Database_of.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Higher versus lower protein intake in formula‐fed term infants
ER  -
TY  - JOUR
AB  - OBJECTIVES: To evaluate the effect of different exercise interventions on depressive symptoms in children and adolescents.

METHODS: Randomized controlled trials (RCT) published until May 2023 were screened in four databases. The Cochrane collaboration tool was used to assess the risk of bias for quality evaluation. Stata 16.0 software was used for both a pairwise meta-analysis and a series of frequentist network meta-analyses (NMA).

RESULTS: A total of 35 RCTs and 5393 participants were included. Aerobic exercise had the most significant effect on depressive symptoms (66.2%), followed by group training (62.5%), resistance exercise (59.0%), and aerobic combined with resistance exercise (57.9%). Furthermore, children and adolescents younger than 15 years showed significant improvement in depressive symptoms (SMD=-0.41, 95% CI (-0.63, -0.19), P &lt; 0.01). The study also found a significant improvement in depression among healthy, obesity, and depressed populations (SMD=-0.25, 95% CI (-0.41, -0.08), P &lt; 0.01); SMD=-0.15, 95% CI (-0.31, -0.00), P &lt; 0.01; SMD=-0.75, 95% CI (-1.32, -0.19), P &lt; 0.01). Additionally, 30 min of exercise had a significant effect (SMD=-0.14, 95% CI (-0,81, -0.01), P &lt; 0.01), and 40-50 min of exercise had the best effect (SMD=-0.17, 95% CI (-0,33, -0.02), P &lt; 0.01). Lastly, exercise frequency of three times per week was significant in children and adolescents (SMD=-0.42, 95% CI (-0,66, -0.18), P &lt; 0.01).

CONCLUSION: Exercise significantly improves depressive symptoms in children and adolescents, with aerobic exercise having the most significant effect. A 12-week, three-times-a-week, 40-50-minute exercise intervention was found to be more effective in younger children and adolescents.
AD  - Li, Jiayu. College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua, 321004, Zhejiang, China.Zhou, Xianxian. College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua, 321004, Zhejiang, China.Huang, Zan. College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua, 321004, Zhejiang, China.Shao, Tianyi. College of Physical Education and Health Sciences, Zhejiang Normal University, Jinhua, 321004, Zhejiang, China. sty123@zjnu.edu.cn.
AN  - 37794338
AU  - Li,
AU  - J.
AU  - Zhou,
AU  - X.
AU  - Huang,
AU  - Z.
AU  - Shao,
AU  - T.
DA  - 10 04
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12889-023-16824-z
DP  - Ovid Technologies
J2  - BMC Public Health
KW  - Humans
KW  - Child
KW  - Adolescent
KW  - Network Meta-Analysis
KW  - Depression/pc [Prevention &amp; Control]
KW  - *Depression
KW  - *Exercise
KW  - Health Services
KW  - Exercise Therapy
L1  - internal-pdf://3511768641/Li-2023-Effect of exercise intervention on dep.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Li, JiayuZhou, XianxianHuang, ZanShao, Tianyi
PY  - 2023
SP  - 1918
T2  - BMC Public Health
TI  - Effect of exercise intervention on depression in children and adolescents: a systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37794338
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37794338&amp;id=doi:10.1186%2Fs12889-023-16824-z&amp;issn=1471-2458&amp;isbn=&amp;volume=23&amp;issue=1&amp;spage=1918&amp;pages=1918&amp;date=2023&amp;title=BMC+Public+Health&amp;atitle=Effect+of+exercise+intervention+on+depression+in+children+and+adolescents%3A+a+systematic+review+and+network+meta-analysis.&amp;aulast=Li&amp;pid=%3Cauthor%3ELi+J%3C%2Fauthor%3E%3CAN%3E37794338%3C%2FAN%3E%3CDT%3EMeta-Analysis%3C%2FDT%3E
UR  - https://bmcpublichealth.biomedcentral.com/counter/pdf/10.1186/s12889-023-16824-z.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - In this meta-analysis, we synthesized 42 between-group studies (N = 4114) evaluating the effectiveness of culturally adapted cognitive behavioral therapy (CA-CBT) on reducing depression and anxiety severity when compared to waitlist/control groups and active alternative treatments. Separate random-effects meta-analyses revealed moderate-to-large effect sizes in favor of CA-CBT on depression and anxiety when compared to active alternative treatments and waitlist/control groups. Independent random-effects models revealed evidence of publication bias and indicated influential moderating effects on anxiety. Implications for counselor practice are discussed.
AN  - WOS:000935118400001
AU  - Silveus,
AU  - S.
AU  - A.
AU  - Schmit,
AU  - M.
AU  - K.
AU  - Oliveira,
AU  - J.
AU  - T.
AU  - Hughes,
AU  - L.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/jcad.12463
L1  - internal-pdf://4174236230/Silveus-2023-Meta-analysis of culturally adapt.pdf
PY  - 2023
SP  - 129-142
T2  - Journal of Counseling and Development
TI  - Meta-analysis of culturally adapted cognitive behavioral therapy for anxiety and depression
UR  - &lt;Go to ISI&gt;://WOS:000935118400001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcad.12463?download=true
VL  - 101
ER  -
TY  - JOUR
AB  - The objective of this research was to assess the efficacy of behavioral therapy interventions in the treatment of autism spectrum disorders (ASD). The study utilized the PubMed and Embase databases to locate randomized controlled trials, quasi-experimental treatment studies, and randomized clinical trial comparisons. The experimental group received treatment based on an applied behavioral approach, such as PECS, DTT, PRT, TEACCH, ESDM, and EIBI. After examining seventeen studies, the researchers found that each type of behavioral intervention had a positive impact. Naturalistic protocols that employed PRT and PECS improved ASD symptoms in general, despite their targeting of particular cognitive domains such as language. ESDM enhanced receptive language, particularly in preschool-aged children. Structured and integrated interventions, like EIBI and TEACCH, improved overall adaptive functioning. Combining DTT with a TEACCH program produced greater benefits in linguistic, affective-social, and personal autonomy domains. However, there is a scarcity of high-quality research available on behavioral interventions for ASD. Further comparative studies are necessary to identify cost-efficient interventions. For example, PRT and PECS significantly improved social communication skills in only 15-40 hours over six months. The authors emphasized the need for continued research and the application of evidence-based interventions in specialized settings.
AD  - Pruneti, Carlo. Clinical Psychology, Clinical Psychophysiology and Clinical Neuropsychology Labs, Department of Medicine and Surgery, University of Parma, Parma, Italy.Coscioni, Gabriella. Journey Autism &amp; Behavioral Care Center, Charlestown, MA, USA.Guidotti, Sara. Clinical Psychology, Clinical Psychophysiology and Clinical Neuropsychology Labs, Department of Medicine and Surgery, University of Parma, Parma, Italy.
AN  - 37803891
AU  - Pruneti,
AU  - C.
AU  - Coscioni,
AU  - G.
AU  - Guidotti,
AU  - S.
DA  - Oct 06
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/13591045231205614
DP  - Ovid Technologies
J2  - Clin
L1  - internal-pdf://1283677135/pruneti-et-al-2023-evaluation-of-the-effective.pdf
LA  - English
M3  - Review
N1  - Pruneti, CarloCoscioni, GabriellaGuidotti, Sara
PY  - 2023
SP  - 13591045231205614
T2  - Clinical Child Psychology &amp; Psychiatry
TI  - Evaluation of the effectiveness of behavioral interventions for autism spectrum disorders: A systematic review of randomized controlled trials and quasi-experimental studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37803891
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37803891&amp;id=doi:10.1177%2F13591045231205614&amp;issn=1359-1045&amp;isbn=&amp;volume=&amp;issue=&amp;spage=13591045231205614&amp;pages=13591045231205614&amp;date=2023&amp;title=Clinical+Child+Psychology+%26+Psychiatry&amp;atitle=Evaluation+of+the+effectiveness+of+behavioral+interventions+for+autism+spectrum+disorders%3A+A+systematic+review+of+randomized+controlled+trials+and+quasi-experimental+studies.&amp;aulast=Pruneti&amp;pid=%3Cauthor%3EPruneti+C%3C%2Fauthor%3E%3CAN%3E37803891%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/10.1177/13591045231205614
ER  -
TY  - JOUR
AB  - To conduct a systematic review of the comparative efficacy of various psychotropic medications for the treatment of disruptive behavior (DBs) in youths. To this aim, we systematically reviewed randomized clinical trials (RCTs) of various psychotropic medications targeting symptoms of DBs and applied network meta-analysis to investigate their relative efficacy. Fifty-five RCTs meeting the inclusion criteria were selected. To predict and interpret relative treatment efficacy, we compared the efficacy of various psychotropic medications prescribed for DB symptoms based on their mechanism of action. Network meta-analysis revealed that for reducing DBs, second-generation antipsychotics, stimulants, and non-stimulant ADHD medications were more efficacious than placebo, and second-generation antipsychotics were the most efficacious. The dopaminergic modulation of top-down inhibitory process by these medications is discussed in this review. This study offers information on the relative efficacy of various psychotropic medications for the treatment of DB, and insight into a potential neurobiological underpinning for those symptoms. It also illustrates the potential utility of these neurobiological mechanisms as a target for future treatment studies. Copyright &copy; 2023. The Author(s).
AU  - Seok,
AU  - J.-W.
AU  - Soltis-Vaughan,
AU  - B.
AU  - Lew,
AU  - B.
AU  - J.
AU  - Ahmad,
AU  - A.
AU  - Blair,
AU  - R.
AU  - J.
AU  - R.
AU  - Hwang,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1038/s41598-023-33979-2
L1  - internal-pdf://0212635828/Seok-2023-Psychopharmacological treatment of d.pdf
PY  - 2023
SP  - 6921
T2  - Scientific Reports
TI  - Psychopharmacological treatment of disruptive behavior in youths: systematic review and network meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medl&amp;NEWS=N&amp;AN=37117632
UR  - https://www.nature.com/articles/s41598-023-33979-2.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - BACKGROUND: Cognitive behavioural therapy (CBT) is effective in treating various neurological and psychiatric diseases. It improves anxiety symptoms in children with autism spectrum disorder, gaining considerable empirical support. However, social skills results are mixed, leading to debate over its effectiveness, highlighting the need for further development. While the Social Responsiveness Scale (SRS) is a secondary indicator to measure anxiety symptoms, it primarily evaluates social skills, which are essential for rehabilitating children with autism. Therefore, evaluating social disorder improvement in children with autism is imperative. Social impairment is a core autism symptom. Therefore, we conducted a systematic review of randomised controlled trials assessing the effects of CBT on social skills in this population.

METHODS: We reviewed articles published in several databases through October 2022 and relevant reference lists. We used the standardised mean difference (SMD) as the main effect size indicator and focused on SRS metrics from baseline to endpoint. We analysed subgroups, heterogeneity, bias risk, and publication bias.

RESULTS: Our meta-analysis included 214 children from seven randomised controlled trials with nine datasets. Forest plot analysis shows CBT improved social skills in children with autism compared to controls. Subgroup analysis revealed parents&#039; and teachers&#039; SRS scores for children, SRS scores of CBT versus waitlist controls, and those of CBT versus non-waiting-list controls.

LIMITATIONS: Most randomised controlled CBT trials for children with autism have explored anxiety symptom improvement. Further, social skill assessment was a secondary outcome or not assessed. Thus, social skills data are insufficient.

CONCLUSIONS: CBT is effective in improving social impairment in children with autism.

REGISTRATION: This meta-analysis was registered with the International Prospective Register of Systematic Reviews (CRD42022363423).
AD  - You, Xiao-Rui. Hebei University of Chinese Medicine, Hebei Province, Shijiazhuang, China.Gong, Xing-Ruo. Hebei University of Chinese Medicine, Hebei Province, Shijiazhuang, China.Guo, Mei-Ran. Hebei University of Chinese Medicine, Hebei Province, Shijiazhuang, China.Ma, Bing-Xiang. The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Henan Province, Zhengzhou, China. Electronic address: mbx1963@126.com.
AN  - 37802322
AU  - You,
AU  - X.
AU  - R.
AU  - Gong,
AU  - X.
AU  - R.
AU  - Guo,
AU  - M.
AU  - R.
AU  - Ma,
AU  - B.
AU  - X.
DA  - Oct 04
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2023.10.008
DP  - Ovid Technologies
J2  - J Affect Disord
L1  - internal-pdf://4138688345/1-s2.0-S0165032723011904-main.cleaned.pdf
LA  - English
N1  - You, Xiao-RuiGong, Xing-RuoGuo, Mei-RanMa, Bing-XiangS0165-0327(23)01190-4
PY  - 2023
SP  - 8-17
T2  - Journal of Affective Disorders
TI  - Cognitive behavioural therapy to improve social skills in children and adolescents with autism spectrum disorder: A meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37802322
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37802322&amp;id=doi:10.1016%2Fj.jad.2023.10.008&amp;issn=0165-0327&amp;isbn=&amp;volume=344&amp;issue=&amp;spage=8&amp;pages=8-17&amp;date=2023&amp;title=Journal+of+Affective+Disorders&amp;atitle=Cognitive+behavioural+therapy+to+improve+social+skills+in+children+and+adolescents+with+autism+spectrum+disorder%3A+A+meta-analysis+of+randomised+controlled+trials.&amp;aulast=You&amp;pid=%3Cauthor%3EYou+XR%3C%2Fauthor%3E%3CAN%3E37802322%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/pii/S0165032723011904?via%3Dihub
VL  - 344
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Adolescents who are socially excluded are at increased risk of mental health problems such as depression and anxiety. Promoting social inclusion could be an effective strategy for preventing and treating adolescent depression and anxiety. 

**METHODS**
We conducted a systematic review of intervention studies which aimed to prevent or treat adolescent depression and/or anxiety by promoting social inclusion. Throughout the review we engaged a youth advisory group of 13 young people (aged 21-24) from Uganda, Turkey, Syria, South Africa, and Egypt. 

**RESULTS**
We identified 12 studies relevant to our review. The interventions tested use a range of different strategies to increase social inclusion and reduce depression and anxiety, including social skills training, psychoeducation, teaching life skills training, and cash transfers. Pooled standardised mean differences (SMDs) based on random-effects models showed medium-to-large benefits of interventions on improving depression and anxiety symptoms (n = 8; SMD = -0.62; 95% CI, -1.23 to -0.01, p &lt; 0.05). 

**CONCLUSION**
Although there are not many studies, those which have been done show promising results that strongly suggest that social inclusion could be an important component of programmes to promote adolescent mental health.
AN  - 36767261
AU  - Hunt,
AU  - X.
AU  - Shakespeare,
AU  - T.
AU  - Vilyte,
AU  - G.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Henry,
AU  - J.
AU  - Bradshaw,
AU  - M.
AU  - Naidoo,
AU  - S.
AU  - Mbuyamba,
AU  - R.
AU  - Aljassem,
AU  - S.
AU  - Suubi,
AU  - E.
AU  - Aljasem,
AU  - N.
AU  - Makhetha,
AU  - M.
AU  - Bantjes,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph20031895
L1  - internal-pdf://1709030870/Hunt-2023-Effectiveness of Social Inclusion In.pdf
PY  - 2023
SP  - 19
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Effectiveness of Social Inclusion Interventions for Anxiety and Depression among Adolescents: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36767261
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-20-01895/article_deploy/ijerph-20-01895-v2.pdf?version=1674999454
VL  - 20
ER  -
TY  - JOUR
AB  - BAKGRUNN:
VIP Snakk om det (tidligere VIP-programmet) er et psykoedukativt program som retter seg mot elever i videregående skoler i alderen 16 og 17 år. Programmet gir informasjon om psykisk helse og psykiske lidelser samt veiledning i hvordan man håndterer slike vansker. Lærere og helsepersonell får opplæring i programmet og hvordan man oppdager problemer hos elevene tidlig for å kunne sette i verk hjelpetiltak gjennom helsesystemet.

METODE:
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

RESULTATER:
VIP Snakk om det er evaluert i et kvasieksperimentelt design med test og kontrollgruppe, der data ble innhentet før intervensjonen, rett etter og 6, 12 og 24 måneder etter. Effektene som gjelder kunnskap om psykiske lidelser er moderate, både rett etter deltakelse i programmet og i etterundersøkelsen. Det er en svakhet at effektene ikke er konsistent rapportert for alle måletidspunkter. Psykiske problemer er bare rapportert for tidsrommet rett etter intervensjonen til ett år etter. På grunn av valgt design og spørreskjema er det vanskelig å sammenlikne effektene med andre resultater i feltet. I tillegg måles angstsymptomer med en skala som har fem spørsmål og uavklart validitet.

KONKLUSJON:
VIP Snakk om det klassifiseres på evidensnivå 3 &ndash; Tiltak med noe dokumentasjon på effekt.
AU  - Neumer,
AU  - S-P.
AU  - Rye,
AU  - M.
AU  - Holen,
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /post_tiltak_arkiv/vip-snak-om-det-2-utg/
L1  - internal-pdf://3832929156/VIP-Snakk-om-det_2-utg.cleaned.pdf
PY  - 2023
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: VIP Snakk om det (2. utg.)
ER  -
TY  - JOUR
AB  - **Purpose**
The aim of this review was to examine the efficacy of dance interventions for individuals with cerebral palsy (CP), measured at any level of the International Classification of Functioning, Disability and Health (ICF).

**Methods**
A systematic review and meta-analysis was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). A comprehensive search of peer-reviewed articles was performed using six electronic databases.

**Results**
Fourteen studies were included in this review, nine of which were also included in the meta-analysis. The meta-analyses yielded a large overall effect for cognitive, motor, and social-emotional function outcomes, with a high degree of heterogeneity between outcome effects, attributable to differences in study design.

**Conclusion**
Although recent studies provide support for the acceptance and efficacy of dance interventions for people with CP, the systematic review revealed significant limitations in study design (only 2 randomised control trials). High-quality research that measures outcomes across all dimensions of the ICF, and particularly at the level of participation, are needed to improve the level of empirical support for dance-based interventions.
AN  - WOS:000975461200001
AU  - Machado,
AU  - E.
AU  - D.
AU  - Cole,
AU  - M.
AU  - H.
AU  - Miller,
AU  - L.
AU  - McGuckian,
AU  - T.
AU  - B.
AU  - Wilson,
AU  - P.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1080/09638288.2023.2200259
L1  - internal-pdf://4050943151/Machado-2023-The efficacy of dance interventio.pdf
PY  - 2023
SP  - 17
T2  - Disability and Rehabilitation
TI  - The efficacy of dance interventions for the activity and participation of individuals with cerebral palsy - a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000975461200001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/09638288.2023.2200259
ER  -
TY  - JOUR
AB  - Attention deficit hyperactivity disorder (ADHD) is a frequently diagnosed neurodevelopmental disorder in children and adolescents. The objective of this review was to synthesize empirical studies that investigated the effects of physical activity (PA) on motor proficiency in this population. A systematic review and meta-analysis were conducted following the cochrane guidelines for systematic reviews. In May 2022, a systematic search of eight electronic databases retrieved 476 results, which were screened independently by two reviewers. Based on the inclusion and exclusion criteria, 12 studies were selected for systematic review, and 10 were included in the meta-analysis. A beneficial effect of PA on overall motor proficiency (SMD = 1.12; 95% CI [0.63 to 1.61]; p &lt; 0.05) was observed. Similar positive effects were found for motor proficiency composites, including object control, fine manual control, and body coordination. These results indicate that PA improves the motor proficiency of children and adolescents with ADHD. Copyright &copy; 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
AU  - Liu,
AU  - H.
AU  - L.
AU  - V.
AU  - Sun,
AU  - F.
AU  - Anderson,
AU  - D.
AU  - I.
AU  - Tse,
AU  - C.
AU  - Y.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10578-023-01546-5
L1  - internal-pdf://0090535838/Liu-2023-The Effect of Physical Activity Inter.pdf
PY  - 2023
T2  - Child Psychiatry and Human Development
TI  - The Effect of Physical Activity Intervention on Motor Proficiency in Children and Adolescents with ADHD: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37245166
UR  - https://link.springer.com/article/10.1007/s10578-023-01546-5
UR  - https://link.springer.com/content/pdf/10.1007/s10578-023-01546-5.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: 
The purpose of this study was to systematically review the effects of intervention experiments led by ordinary teachers to improve students&#039; mental health literacy and to provide evidence-based research and new ideas for improving students&#039; mental health literacy. 

METHODS: 
A systematic search using 5 English (Web of Science, PubMed, ProQuest, EBSCO, Springer Link) and 3 Chinese (CNKI, WanFang, and VIP) databases was initiated to identify controlled trials assessing the immediate effect and delay effect of the intervention experiment led by ordinary teachers on improving students&#039; mental health knowledge, anti-stigma, willingness, or behavior to seek-help. 

RESULTS: 
A total of 14 experiments with 7873 subjects were included. The results showed that the immediate effect of the intervention on promoting students&#039; mental health knowledge [g = 0.622, 95% CI (0.395, 0.849)] and anti-stigma [g = 0.262, 95% CI (0.170, 0.354)] was significant, but the amount of delay effect is not significant. 

CONCLUSIONS: 
The results of this review show that ordinary classroom teachers can effectively participate in projects to improve students&#039; mental health literacy, significantly improve students&#039; mental health knowledge and attitudes towards psychological problems, and make up for the shortage of full-time mental health teachers in schools. In future, more attention should be paid to students&#039; mental health literacy, and evidence-based intervention research should be strengthened. Furthermore, we can improve students&#039; mental health literacy and avoid poor mental health by addressing delays in early intervention, as well as improve experimental design, prolong the intervention time, and improve the effectiveness of the intervention.
AN  - 36673704
AU  - Liao,
AU  - Y.
AU  - Ameyaw,
AU  - M.
AU  - A.
AU  - Liang,
AU  - C.
AU  - Li,
AU  - W.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/ijerph20020949
L1  - internal-pdf://2587015970/Liao-2023-Research on the Effect of Evidence-B.pdf
PY  - 2023
SP  - 04
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Research on the Effect of Evidence-Based Intervention on Improving Students&#039; Mental Health Literacy Led by Ordinary Teachers: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36673704
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-20-00949/article_deploy/ijerph-20-00949-v2.pdf?version=1673855442
VL  - 20
ER  -
TY  - JOUR
AB  - INTRODUCTION: Anxiety disorders are the most prevalent psychiatric disorders among youth. Among the various anxiety disorders, generalized anxiety disorder is particularly prevalent. Youth with GAD appear at elevated risk of developing other anxiety disorders, mood disorder, and substance use disorders. Functional outcomes of youth with GAD can be improved through early recognition and treatment, thus promoting better longer-term outcomes. 

AREAS COVERED: The current article summarizes evidence-based state-of-the-art pharmacotherapy for pediatric GAD based on open-label, randomized, and controlled trials. Two electronic databases (PubMed and Scopus) were systematically searched in April 2022 for relevant publications. 

EXPERT OPINION: The literature supports a combination of psychotherapy and pharmacotherapy as being associated with better outcomes when compared to mono-therapies. While longer-term follow-ups are limited, one such study does challenge this notion. Both selective serotonin reuptake inhibitors (SSRIs) and selective norepinephrine reuptake inhibitors (SNRIs) have been found across studies to have moderate effect sizes in the treatment of pediatric anxiety disorders. SSRIs continue to be a first-line intervention, whereas SNRIs may be considered a second-line treatment. While more evidence is needed, there are emerging data indicating that SSRIs are associated with a more rapid and greater reduction in anxiety symptoms when compared to SNRIs.
AN  - 37074259
AU  - Castagna,
AU  - P.
AU  - J.
AU  - Farahdel,
AU  - E.
AU  - Potenza,
AU  - M.
AU  - N.
AU  - Crowley,
AU  - M.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/14656566.2023.2199921
L1  - internal-pdf://1349324439/Castagna-2023-The current state-of-the-art in.pdf
PY  - 2023
SP  - 835-847
T2  - Expert Opinion on Pharmacotherapy
TI  - The current state-of-the-art in pharmacotherapy for pediatric generalized anxiety disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=37074259
UR  - https://www.tandfonline.com/doi/full/10.1080/14656566.2023.2199921
UR  - https://www.tandfonline.com/doi/pdf/10.1080/14656566.2023.2199921
VL  - 24
ER  -
TY  - JOUR
AB  - Animal-assisted therapy (AAT) is becoming increasingly popular. The possibilities and guidelines for interventions and methods are very diverse. Currently, published studies mainly concentrate on effects in paediatrics, outpatient therapy and schools. Specific recommendations for AAT in the context of inpatient child and adolescent psychiatry do not exist. This systematic review will attempt to evaluate the existing studies in terms of their methodological quality and specify positive and negative effects, aiming to provide a decision-making aid for everyday clinical practice. A systematic literature search (PubMed/MEDLINE, APA PsycINFO, PubPsych, ProQuest, Google Scholar, and Cochrane Library) according to the PRISMA criteria resulted in 1,908 identified hits, of which 49 articles were reviewed in full text. Three raters contributed to the review of the articles using a criteria-guided codebook. This systematic review is listed in the PROSPERO database (CRD42022358909). Quality analysis was conducted using Effective Public Health Practice Project (EPHPP). Five studies were identified. The majority of these showed deficits in quality. Therapeutic effects and positive influences on the psychopathological status, interpersonal relationships and subjective well-being or attitudes towards canine-assisted therapy (CAT) could be identified. Current studies indicate positive therapeutic effects of CAT in the inpatient treatment of children and adolescents. A cautiously positive perspective is warranted, but a general recommendation for CAT cannot be given. CAT should be carefully considered, planned, and implemented by professionals. For the future, further randomised controlled studies including follow-up studies, larger subject groups and clinically evaluated interventions are necessary to validate the current results.
AN  - 38147109
AU  - Fornefeld,
AU  - D.
AU  - Zellin,
AU  - U.
AU  - Schmidt,
AU  - P.
AU  - Fricke,
AU  - O.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-023-02326-1
L1  - internal-pdf://2272864916/Fornefeld-2023-The supporting role of dogs in.pdf
PY  - 2023
SP  - 26
T2  - European Child &amp; Adolescent Psychiatry
TI  - The supporting role of dogs in the inpatient setting: a systematic review of the therapeutic effects of animal-assisted therapy with dogs for children and adolescents in an inpatient setting
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38147109
UR  - https://link.springer.com/content/pdf/10.1007/s00787-023-02326-1.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - Due to prevalent exposure to trauma in the biological family, children in foster care often experience post-traumatic stress symptoms, difficulties in forming secure attachments with the caregivers, and can present a complex range of symptoms and impairments across several areas of development. Therefore, there is an increased necessity for interventions on the effects of trauma exposure in foster care. 

This is the first meta-analysis to investigate the effectiveness of interventions on the effects of trauma exposure in foster care against control groups. Twelve randomized controlled trials on interventions for children with trauma-related diagnoses or with other mental health problems that are a result of complex trauma were included. A random-effects model was used for pooling the effect sizes, which were calculated for trauma-related outcomes at posttreatment and follow-up. Several potential moderator variables were analyzed. The results showed that participants receiving the intervention on trauma-related problems reported significantly better outcomes than those in the control conditions at posttreatment, after the exclusion of one outlier (g = 0.39; 95% CI [0.18 to 0.62]). The effect size was smaller at follow-up (g = 0.24; 95% CI [0.03 to 0.46]), but significant. Clinical diversity, methodological diversity, as well as other limitations were identified and discussed. 

Overall, the findings highlight the potential of interventions for trauma-related problems in foster care. These findings bring important contributions to the child welfare system in their efforts to develop and adapt suitable interventions for children with mental health problems due to trauma.
AN  - WOS:001017732300001
AU  - Teculeasa,
AU  - F.
AU  - Golu,
AU  - F.
AU  - Gorbanescu,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1007/s40653-023-00563-9
L1  - internal-pdf://3398119685/Teculeasa-2023-The Effectiveness of Psychologi.pdf
PY  - 2023
SP  - 16
T2  - Journal of Child &amp; Adolescent Trauma
TI  - The Effectiveness of Psychological Interventions on the Impact of Trauma Exposure in Foster Care: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001017732300001
UR  - https://link.springer.com/article/10.1007/s40653-023-00563-9
UR  - https://link.springer.com/content/pdf/10.1007/s40653-023-00563-9.pdf
ER  -
TY  - JOUR
AB  - Most substance use begins in adolescence. Both childhood trauma and associated post-traumatic stress disorder (PTSD) increase risk for early substance use, which is associated with greater eventual severity of substance use disorders (SUDs). When co-occurring, PTSD and SUD can reinforce and exacerbate each other, necessitating integrated treatment approaches. 

To systematically review existing literature on interventions for prevention or treatment of SUDs among adolescents (aged 10-24) with a history of trauma, with or without PTSD, we searched databases (PubMed, PsycInfo, CINAHL, Cochrane CENTRAL) using search terms related to substance use, trauma, adolescents, and interventions. Searches identified 8134 unique articles, 68 of which prompted full-text screening. Authors extracted data, applied the Effective Public Health Practice Project Quality Assessment Tool to evaluate the evidence, and synthesized findings. 

Thirty three articles met eligibility criteria, including 13 RCTs. Twenty studies (10 RCTs) evaluated interventions for substance use and co-occurring problems among youth with a history of trauma, predominantly via individual therapy based on cognitive-behavioral principles, although group therapy, case management, and other approaches have also been studied. Interventions with exposure-based components were infrequent but had robust results and minimal adverse outcomes. Thirteen studies examined differential response of youth with a history of trauma to standard SUD treatments, compared to youth without a history of trauma, with mixed findings. 

Youth with a history of trauma face elevated risk of SUDs and may respond differently to SUD treatments. Several promising interventions have been recently developed.
AN  - 37480386
AU  - Becker,
AU  - T.
AU  - D.
AU  - Castaneda
AU  - Ramirez,
AU  - S.
AU  - Bruges
AU  - Boude,
AU  - A.
AU  - Leong,
AU  - A.
AU  - Ivanov,
AU  - I.
AU  - Rice,
AU  - T.
AU  - R.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s00787-023-02265-x
L1  - internal-pdf://1409485567/Becker-2023-Interventions for prevention and t.pdf
PY  - 2023
SP  - 22
T2  - European Child &amp; Adolescent Psychiatry
TI  - Interventions for prevention and treatment of substance use in youth with traumatic childhood experiences: a systematic review and synthesis of the literature
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37480386
UR  - https://link.springer.com/article/10.1007/s00787-023-02265-x
UR  - https://link.springer.com/content/pdf/10.1007/s00787-023-02265-x.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - PURPOSE: The purpose of this article is to examine the efficacy of oxytocin in treating core symptoms of autism spectrum disorder (ASD) with children. 

METHODS: A systematic literature search was conducted to identify randomized controlled trials (RCTs) of oxytocin for the treatment of core symptoms in children with ASD. The search included studies published between January 1, 1999 and March 15, 2023, that were randomized, single or double-blinded, and included a placebo control group. Standard screening rules were applied to select relevant studies, resulting in the inclusion of five RCTs involving 486 children with ASD. 

RESULTS: Ultimately, a total of five RCTs, involving 486 children with ASD, were included in the review using standard screening rules.One of the included studies demonstrated a statistically significant improvement in Social Responsiveness Scale (SRS) and Repetitive Behavior Scale-Revised (RBS) scores when children with ASD were treated with oxytocin (24 IU/2 days for 6 weeks). The improvement in core symptoms persisted at the 6-month follow-up. The meta-analysis findings suggested that oxytocin might have a moderate effect in improving the core symptom of narrow interests and repetitive stereotyped behaviors in children with ASD. 

CONCLUSION: While the therapeutic value of oxytocin in treating core symptoms of ASD in children is not fully established, the results of this meta-analysis indicate a potential moderate effect. However, further studies with larger sample sizes and more robust RCTs are needed to directly demonstrate the efficacy of oxytocin. Future research should also focus on effect size and outcome evaluation accuracy while minimizing bias in RCT experiments.
AN  - 37540265
AU  - Hu,
AU  - L.
AU  - Du,
AU  - X.
AU  - Jiang,
AU  - Z.
AU  - Song,
AU  - C.
AU  - Liu,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00228-023-03545-w
L1  - internal-pdf://0601045497/Hu-2023-Oxytocin treatment for core symptoms i.pdf
PY  - 2023
SP  - 04
T2  - European Journal of Clinical Pharmacology
TI  - Oxytocin treatment for core symptoms in children with autism spectrum disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37540265
UR  - https://link.springer.com/article/10.1007/s00228-023-03545-w
UR  - https://link.springer.com/content/pdf/10.1007/s00228-023-03545-w.pdf
VL  - 04
ER  -
TY  - JOUR
AB  - Background: The growing problem of adolescent mobile phone addiction has attracted significant attention, underscoring the importance of identifying approaches to address it. Exercise has been found to reduce adolescent mobile phone addiction; however, its mechanism remains unclear. This review aims to elucidate the potential moderating factors between exercise and mobile phone addiction based on previous studies to provide a reference for adolescents to effectively participate in exercise to reduce mobile phone addiction. 

Methods: Articles were searched in the CNKI, Web of Science, Scopus, Cochrane, PsycINFO, and PubMed databases according to the inclusion criteria and followed the Preferred Reporting Items for Systematic Assessment and Meta-analysis (PRISMA). The quality of the literature was assessed by two independent reviewers using the Cochrane Collaboration Risk of Bias tool for methodological quality assessment. Meta-analysis was performed using Stata 15.1 software for Meta-analysis, standardized mean difference (SMD) was combined using a random effects model, and subgroup analysis was used to explore heterogeneity. 

Results: A total of 12 studies, 17 samples, and 861 subjects were included in the meta-analysis, and all studies were randomized controlled trials. The findings revealed that the exercise intervention significantly reduced mobile phone addiction in adolescents (SMD = -3.11; 95% CI: -3.91, -2.30; p &lt; 0.001). The intervention effect was moderated by multiple variables, such as the measurement tools, exercise intervention types, cycles, frequency, and duration of a single exercise intervention. 

Conclusion: Our findings suggest that exercise could serve as an effective strategy for preventing or ameliorating mobile phone addiction in adolescents. Based on the results of this study, we encourage mobile phone-addicted adolescents to engage in a single exercise using a mix of skills for 30-60 min three or more times weekly for more than eight consecutive weeks.
AN  - 38192396
AU  - Li,
AU  - Z.
AU  - Xia,
AU  - X.
AU  - Sun,
AU  - Q.
AU  - Li,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fpsyg.2023.1294116
L1  - internal-pdf://0526999037/Li-2023-Exercise intervention to reduce mobile.pdf
PY  - 2023
SP  - 1294116
T2  - Frontiers in Psychology
TI  - Exercise intervention to reduce mobile phone addiction in adolescents: a systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=38192396
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773895/pdf/fpsyg-14-1294116.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - **PURPOSE:**

Early language and communication interventions for children with language impairments have been shown to be effective in assessments administered immediately after treatment. The purpose of the current systematic review and meta-analysis was to assess the overall durability of those effects over time and whether durability was related to outcome type, etiology of child language impairments, implementer of intervention, magnitude of posttest effects, time between intervention and follow-up, and study risk of bias. 

**METHOD:**

 We conducted a systematic search of online databases and reference lists to identify experimental and quasi-experimental group design studies. All studies tested the effects of early communication interventions at least 3 months post-intervention. Participants were children 0-5 years old with language impairments. Coders identified study features and rated methodological quality indicators for all studies. Effect sizes at long-term timepoints and associations with potential moderators were estimated using multilevel meta-analysis with robust variance estimation. 

**RESULTS:**

Twenty studies with 129 long-term outcome effect sizes met inclusion criteria. Studies included children with developmental language disorders or language impairment associated with autism. The overall average effect size was small and significant (g = .22, p = .002). Effect size estimates were larger for prelinguistic outcomes (g = .36, p &lt; .001) than for linguistic outcomes (g = .14, p = .101). Significant factors were the posttest effect sizes, the risk of bias for randomized trials, and etiology of language impairment for linguistic outcomes. Time post-intervention did not significantly predict long-term effect sizes. 

**CONCLUSIONS:**

Outcomes of early language and communication interventions appear to persist for at least several months post-intervention. More research is needed with collection and evaluation of long-term outcomes, a focus on measurement, and consistency of primary study reporting. 

**SUPPLEMENTAL MATERIAL:**
 https://doi.org/10.23641/asha.23589648.
AN  - 37418755
AU  - Pak,
AU  - N.
AU  - S.
AU  - Chow,
AU  - J.
AU  - C.
AU  - Dillehay,
AU  - K.
AU  - M.
AU  - Kaiser,
AU  - A.
AU  - P.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1044/2023_JSLHR-22-00711
L1  - internal-pdf://3320063372/Pak_2023.pdf
PY  - 2023
SP  - 1-16
T2  - Journal of Speech Language &amp; Hearing Research
TI  - Long-Term Effects of Early Communication Interventions: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37418755
ER  -
TY  - JOUR
AB  - OBJECTIVE: 
The effectiveness of neuropsychological rehabilitation is supported by the evidence found in previous reviews, but there is a lack of research regarding the effectiveness of remotely conducted neuropsychological rehabilitation. This review aimed to identify and evaluate the results of studies investigating the effectiveness of teleneuropsychological rehabilitation. 

METHODS: 
Relevant articles were extracted from electronic databases and filtered to include studies published in 2016 or later to focus on recent practices. Data were synthesized narratively. 

RESULTS: 
A total of 14 randomized controlled studies were included in the synthesis (9 for children/adolescents, 5 for adults). The most common type of intervention was computerized cognitive training with regular remote contact with the therapist (seven studies). Regarding children and adolescents, the evidence for the effectiveness was found only for these types of interventions with improvements in cognitive outcomes. The results regarding the family-centered interventions were mixed with improvements only found in psychosocial outcomes. No support was found for the effectiveness of interventions combining cognitive and motor training. Regarding adults, all included studies offered support for the effectiveness, at least to some extent. There were improvements particularly in trained cognitive functions. Long-term effects of the interventions with generalization to global functioning remained somewhat unclear. 

CONCLUSION: 
Remote interventions focused on computerized cognitive training are promising methods within teleneuropsychological rehabilitation. However, their impact on long-term meaningful, everyday functioning remained unclear. More research is needed to reliably assess the effectiveness of teleneuropsychological interventions, especially with more comprehensive approaches.
AN  - 37746802
AU  - Naamanka,
AU  - E.
AU  - Salakka,
AU  - I.
AU  - Parkkila,
AU  - M.
AU  - Hotti,
AU  - J.
AU  - Poutiainen,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1017/S1355617723000565
L1  - internal-pdf://0321589821/Naamanka-2023-Effectiveness of teleneuropsycho.pdf
PY  - 2023
SP  - 1-18
T2  - Journal of the International Neuropsychological Society
TI  - Effectiveness of teleneuropsychological rehabilitation: Systematic review of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37746802
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/08ED8875463338F83F282E4533E0D084/S1355617723000565a.pdf/div-class-title-effectiveness-of-teleneuropsychological-rehabilitation-systematic-review-of-randomized-controlled-trials-div.pdf
ER  -
TY  - JOUR
AB  - **OBJECTIVES**
This systematic review aimed to identify and appraise studies investigating the efficacy of mindfulness-based interventions (MBIs) for improving depression, anxiety and parental stress in families affected by childhood physical illnesses, as well as feasibility and acceptability. 

**METHODS**
Embase, PsycINFO, Scopus, Medline, and PubMed were searched between February 2 and 17, 2021, and updated on August 5, 2022. Studies investigating MBIs with children and adolescents (&lt;18 years) with physical health conditions were included, and results are presented with narrative synthesis. 

**RESULTS**
Eighteen studies met eligibility criteria. Studies included children and adolescents with chronic pain, headaches, cancer, heart conditions, esophageal atresia, inflammatory bowel disease, and polycystic ovary syndrome. Most studies reported mindfulness was feasible and acceptable, although findings for different health conditions were mixed. Some studies encountered difficulties with attrition, resulting in findings being underpowered. 

**CONCLUSIONS**
MBIs show promise for improving anxiety and depression in children with physical health conditions, but there is limited support for reducing stress in the family unit. A potential direction for future research might be the inclusion of parents. However, because of the heterogeneity of studies included in this review, findings must be cautiously interpreted.
AN  - 36786779
AU  - Hughes,
AU  - O.
AU  - Shelton,
AU  - K.
AU  - H.
AU  - Penny,
AU  - H.
AU  - Thompson,
AU  - A.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/jpepsy/jsad003
L1  - internal-pdf://3174153530/Hughes-2023-Living With Physical Health Condit.pdf
PY  - 2023
SP  - 14
T2  - Journal of Pediatric Psychology
TI  - Living With Physical Health Conditions: A Systematic Review of Mindfulness-Based Interventions for Children, Adolescents, and Their Parents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36786779
UR  - https://watermark.silverchair.com/jsad003.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAuAwggLcBgkqhkiG9w0BBwagggLNMIICyQIBADCCAsIGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMpC3B0eB1kKNApCVPAgEQgIICkybJkJ4rR4xu4FNJ_XAOEfL4cxStscDr1Rf9K3zMtrsTU-Atp7jQdk8Ajdtsqtrv-05mFqjhKUTZV_jYhCXj3SYVWN-k1JBtU0aQbPJ-6vnlGxkP9OAIg5axoQsf8k8F6Dt8aLMb-4JvsMcV-ADpVJL110z3PEwrDlYhNSud0Ap2HJgJ1juT5c-NLNKWuzVHg66WYdAKYu2981toLESYdMhamBTLT3eti7OiZ157dzQefH4DBq803FMGoHBAC9jTWFcuggZSNmEyCIM7I4u6C_YSaOOzwY6wTpUyO7GyuvchCuh7jSzbx-Kf4XWZ4SdbRy7SuKhWuftsBVQQW99H5c9rxd8aY_VQA5bGICV_ENePOq4SrkormOhn-pVhA1TeVd9SHbqV0a9T4UuXZRiYOk3fBWE2aGdiSaTLmZL8dRxHJkc2D2gK8_w8MF8FW5Zh3HM9INd0BhTT-mP1Ng53eiABR30-LYNfqCHxGcuB-rykmsT8kBAUofKJ8_ymiVfFncHcDHsmNnF6Rik8q_zmd_wft24UPTkmNpdk_sh0C7tJVD8cgLsZSuw8GLx_KddiLQKOS5N2A4XlHa9k09mSRLcdx_976eVBtQ7iJsJwaT6jEztqRcKU6Uxh2JxFklcFuCvAqSe-f9XlBiZKp8tTGHiNpeB0IUoSTmU_JjT1UzFu8vugFLNWt4ZdO3Yf7UyXRxdE0KcCTvkhCk0pidc6w23jpKX8qFabLQgqVzFTOhWM9OuSpFtwXDULYNL_pQlK2X5Niavt3VKhR-F-GI9sbzv2RwRSVGQquh2qDMy-D3_05EyBYURqb9HsmVZy-15TMF3PzSRrb39Hq53Cjayk-IKVx_F-H9ab5rNzeEiH8Uu9u4rQ
VL  - 14
ER  -
TY  - JOUR
AB  - BACKGROUND AND OBJECTIVES: Evidence is needed on effective approaches to build parents&#039; ability to promote child development feasible in low- and middle-income countries. Our objective was to synthesize impact of the Reach Up early childhood parenting program in several low- and middle-income countries and examine moderation by family and implementation characteristics.

METHODS: Systematic search using PubMed and Academic Search Elite/EBSCO Host. Randomized controlled trials of the Reach Up program from 1985 to February 2022 were selected. Data were extracted by 2 independent researchers. Primary outcomes were child cognitive, language, and motor development. Secondary outcomes were home stimulation and maternal depressive symptoms. We synthesized pooled effect sizes using random effect inverse-variance weighting and effect modification by testing pooled subgroup effect estimates using the chi2 test for heterogeneity.

RESULTS: Average effect size across 18 studies ranged from 0.49 (95% confidence interval [CI] 0.32 to 0.66) for cognition, 0.38 (CI 0.24 to 0.51) for language, 0.27 (CI 0.13 to 0.40) for motor development, 0.37 (CI 0.21 to 0.54) for home stimulation, and -0.09 (CI -0.19 to 0.01) for maternal depressive symptoms. Impacts were larger in studies targeted to undernourished children, with mean enrollment older than age 12 months and intervention duration 6 to 12 months. Quality of evidence assessed with the Cochrane Assessment of Risk of Bias and GRADE system was moderate. Instruments used to assess child development varied. In moderator analyses, some subgroups included few studies.

CONCLUSIONS: Reach Up benefits child development and home stimulation and is adaptable across cultures and delivery methods. Child and implementation characteristics modified the effects, with implications for scaling. Copyright &copy; 2023 by the American Academy of Pediatrics.
AU  - Jervis,
AU  - P.
AU  - Coore-Hall,
AU  - J.
AU  - Pitchik,
AU  - H.
AU  - O.
AU  - Arnold,
AU  - C.
AU  - D.
AU  - Grantham-McGregor,
AU  - S.
AU  - Rubio-Codina,
AU  - M.
AU  - Baker-Henningham,
AU  - H.
AU  - Fernald,
AU  - L.
AU  - C.
AU  - H.
AU  - Hamadani,
AU  - J.
AU  - Smith,
AU  - J.
AU  - A.
AU  - Trias,
AU  - J.
AU  - Walker,
AU  - S.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1542/peds.2023-060221D
L1  - internal-pdf://2889453013/Jervis-2023-The Reach Up Parenting Program, Ch.pdf
PY  - 2023
T2  - Pediatrics
TI  - The Reach Up Parenting Program, Child Development, and Maternal Depression: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medl&amp;NEWS=N&amp;AN=37125892
UR  - https://watermark.silverchair.com/peds_2023060221d.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtkwggLVBgkqhkiG9w0BBwagggLGMIICwgIBADCCArsGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMsLL12_5QTXzpFw0dAgEQgIICjC2E9x9sYHvHJav2atKEpJLLypotSeHVdrqheEG7L7QKAI5xtVvy395P2wQ60n2RqB0JguPSq92ZaK2vx-gRLpUBH4rQFTieiI259QuuqPJddJIyN53aYMp0kUXMPjTkYCdcLhJWeQoOgEua59XMR7OsDFGYkSTL-CM_tOrCmGqV2oU7bgwqf-0SI6ZRJZT_ceHjy-y_hkZO_lgJIr-xapVHc2EMZ8U7Alx6fVALk3tGV7EPR39_BowmM8r0tkgxri7XVNR5kCs4bobCtgpyJapX_V7N6_n-Z3fFnAYcNF2bfMMMuDKq6pIBnVsHFdIaoG2iyznfDlXwdHHh937_3IvwwMyEMKDI0m_DWk9t-JGtOlPCdItl8rFjFvj5vjaKwBTdEXz9xkuwcc5ySsYQra2SV2s6AzvQ2I9d03HGIXQ8UJ0A1fLw3erheeoVmHNPQgqDSbhcFQh25n4U_fi7CJAyy7XS95FAuhqNQ05vEUyJgW1kV7BPZ2IVhsj6vK5dWk9Vdr_494donbrXV6j3SXZwz1B4u-W0YIP7HqTDnuka6TgWGVi6wdXrVcFrgCXtkJH86oiRF33GIJq23e-Oq7u-AhT9Syq8PxyWvaI9PsZF6e4JmxcKXE45lrquC1E6a8vhlv0d3XmdTKXU5GKrZeS8ZgFJT2KI8__s9iitnI-7mm1JvhcR4Crd0pqqOCe908RzN3yzAgt0-1Vfpb6yhE980qDq3VRixamgutL1cF-V1VRGrXoRb_40R7JVF7jn1YaWKskh3jDeWKugpYR_jZ4hTY3jYhz-2sw2pP5E5o_Be7BKFS8hstClA2D5nxlgIIn8vhA3uNGRLe48ZRfCrxKmUQ5bNMCBQIA3vr8
VL  - 151
ER  -
TY  - JOUR
AB  - Increasingly more research is showing that stress has an influence on the development and maintenance of externalizing problem behavior in adolescents. Stress, for example, causes more impulsivity and limits emotion regulation. Mindfulness focuses on stress reduction and therefore appears to be a (supportive) treatment option with added value for adolescents with externalizing problem behavior. A multilevel meta-analysis (14 studies and 48 effect sizes) was conducted to gain more insight into the effectiveness of this treatment form in reducing externalizing problem behavior. It specifically considered whether the involvement of parents or other combined forms of treatment influenced the effect. The results showed that mindfulness-based interventions are effective in reducing externalizing problem behavior in adolescents, with a large effect size (d = 0.99). The effect was found to be even greater (d = 1.14) after correction for selection bias. The moderator analysis revealed that none of the variables examined had an impact on the effect of mindfulness-based interventions. The results of the moderator analysis should be interpreted with caution. Due to the fact that parents were not involved intensely enough, were barely motivated, and no follow-up data are known about the effectiveness. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AU  - Hoogsteder,
AU  - L.
AU  - M.
AU  - Van
AU  - Os,
AU  - R.
AU  - C.
AU  - J.
AU  - Lutjens,
AU  - J.
AU  - B.
AU  - Sweers,
AU  - N.
AU  - Stams,
AU  - G.-J.
AU  - M.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/str0000285
L1  - internal-pdf://1081377419/2023-32815-001.cleaned (1).pdf
PY  - 2023
SP  - No-Specified
T2  - International Journal of Stress Management
TI  - A multilevel meta-analysis on the effect of mindfulness-based interventions in reducing externalizing problem behavior in adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=psyc21&amp;NEWS=N&amp;AN=2023-32815-001
ER  -
TY  - JOUR
AB  - **Background** 
Selective mutism (SM) is an anxiety disorder that often starts in early years with serious and lasting consequences. Nonpharmacological interventions are commonly seen as the preferred first treatment. This systematic review identifies outcome measures used and outcomes achieved for nonpharmacological interventions for children and adolescents with SM. 

**Methods** 
Systematic searches were conducted using 13 electronic databases and hand searches, including peer-reviewed and grey literature since 1992. 

**Results** 
Twenty-five studies were identified. While specific measures varied, all studies reported an outcome measure for speaking behaviour and 18 used a measure of anxiety. Few studies reported measures of SM remission (k = 6), well-being (k = 6), academic impact (k = 2), or quality of life (k = 1). Within subject outcomes for nonpharmacological interventions were variable for improvements in speaking behaviours (very small to large positive effects) and reduction in anxiety symptoms (very small negative to large positive effects). Only five randomised controlled trials (RCTs) were included in the meta-analysis. Three studies compared a combined systems/behavioural approach with waitlist controls indicating a significant and large effect (Hedges g = 1.06, p &lt; .0001, 95% CI: 0.57-1.56) on improved speaking behaviour. Two of these RCTs showed a large effect for SM remission favouring the intervention (Risk Ratio = 4.25, p = .1774, 95% CI: 0.52-34.84) but this did not reach statistical significance. Non-significant outcomes for two RCTs with active controls (Hedges g = 0.55, p &lt; .2885, 95% CI: -0.47 to 1.57) showed considerable heterogeneity in approach and outcomes, one with large and one with negligible effects.

**Conclusion** 
Despite the considerable impairment caused by SM, there has been little systematic evaluation of non-pharmacological interventions. Although combined systems/behavioural interventions are promising, further systematic evaluations are urgently needed to inform treatment approaches. Cross-study measurement harmonisation is required to promote learning from all studies, including wider clinical and economic outcomes. Clinical Trial Registration Not applicable. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AU  - Hipolito,
AU  - G.
AU  - Pagnamenta,
AU  - E.
AU  - Stacey,
AU  - H.
AU  - Wright,
AU  - E.
AU  - Joffe,
AU  - V.
AU  - Murayama,
AU  - K.
AU  - Creswell,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/jcv2.12166
L1  - internal-pdf://2796717011/Hipolito-2023-A systematic review and meta-ana.pdf
PY  - 2023
SP  - No-Specified
T2  - JCPP Advances
TI  - A systematic review and meta-analysis of nonpharmacological interventions for children and adolescents with selective mutism
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=psyc21&amp;NEWS=N&amp;AN=2023-70761-001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcv2.12166?download=true
ER  -
TY  - JOUR
AB  - The availability of digital tools aiming to promote adolescent mental health is rapidly increasing. However, the field lacks an up-to-date and focused review of current evidence. This study thus looked into the characteristics and efficacy of digital, evidence-based mental health programs for youth (11-18 years). The selection procedure followed the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines and resulted in 27 eligible studies. The high heterogeneity of the results calls for careful interpretation. Nevertheless, small, but promising, effects of digital tools were found with respect to promoting well-being, relieving anxiety, and enhancing protective factors. Some important factors influencing overall efficacy include the given setting, the level of guidance and support, and the adherence to the intervention.
AN  - 36754917
AU  - Wright,
AU  - M.
AU  - Reitegger,
AU  - F.
AU  - Cela,
AU  - H.
AU  - Papst,
AU  - A.
AU  - Gasteiger-Klicpera,
AU  - B.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s10964-023-01735-4
L1  - internal-pdf://1501172236/Wright-2023-Interventions with Digital Tools f.pdf
PY  - 2023
SP  - 754-779
T2  - Journal of Youth &amp; Adolescence
TI  - Interventions with Digital Tools for Mental Health Promotion among 11-18 Year Olds: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=36754917
UR  - https://link.springer.com/content/pdf/10.1007/s10964-023-01735-4.pdf
VL  - 52
ER  -
TY  - JOUR
AB  - BACKGROUND: Impaired executive function is a core symptom of cognitive impairment in atypical children. The purpose of this systematic review and meta-analysis is to explore the effectiveness of interventions for exercise in real-life settings on executive function in atypical children.

METHODS: This study searched the CNKI, Wan-Fang, VIP, WOS, PubMed, Scopus and EBSCO databases. Two researchers independently selected articles, extracted data and assessed the risk of bias for the included studies. Exercise activities were categorized into open and closed skills based on the unpredictability of the environmental context and into sequential and continuous skills based on the complexity of the movement structure. Based on these two classifications, motor skills were categorized into open-sequential (e.g. basketball), open-continuous (e.g. obstacle running), closed-sequential (e.g. martial arts) and closed-continuous (e.g. swimming) skills. The SPSS 25.0 and Stata 16.0 software were used for statistical analysis.

RESULTS: A total of 19 articles (23 studies) were included in the systematic review and meta-analysis. The participants were 990 atypical children with neurodevelopmental disorders. Physical exercise in real-world settings had significant intervention effects on inhibitory control (SMD = -0.592, P = 0.033), working memory (SMD = -0.473, P = 0.034) and cognitive flexibility (SMD = -0.793, P = 0.014) in atypical children. Quantitative intervention characteristics and motor skill types moderated the effect of exercise on promoting executive function in atypical children. Overall, exercise for 30-50 min, three to seven times a week for less than 10 weeks is effective in improving executive function in atypical children. Open skills and sequential skills have a positive intervention effect on more dimensions of executive function in atypical children.

CONCLUSIONS: Physical exercise in real-world settings has a positive intervention effect on executive function in atypical children. We should design interventions based on the personality traits of the subject and the type of exercise they are interested in to better promote improved executive function in atypical children.
AD  - Shi, Peng. School of Physical Education, Shanghai University of Sport, Shanghai, China.Zhang, Ziyun. School of Life and Health, Huzhou College, Huzhou, China.Feng, Xiaosu. School of Physical Educaiton, Liaoning Normal University, Dalian, China.Li, Chenyang. Department of Physical Education, Huaiyin Institute of Technology, Huaian, China.Tang, Yan. School of Physical Education, Shanghai University of Sport, Shanghai, China.
AN  - 37873578
AU  - Shi,
AU  - P.
AU  - Zhang,
AU  - Z.
AU  - Feng,
AU  - X.
AU  - Li,
AU  - C.
AU  - Tang,
AU  - Y.
DA  - Oct 24
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/cch.13182
DP  - Ovid Technologies
J2  - Child Care Health Dev
L1  - internal-pdf://1016356150/Shi-2023-Effect of physical exercise in real-w.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingOctShi, PengZhang, ZiyunFeng, XiaosuLi, ChenyangTang, Yan
PY  - 2023
SP  - 24
T2  - Child: Care, Health &amp; Development
TI  - Effect of physical exercise in real-world settings on executive function of atypical children: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37873578
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37873578&amp;id=doi:10.1111%2Fcch.13182&amp;issn=0305-1862&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2023&amp;title=Child%3A+Care%2C+Health+%26+Development&amp;atitle=Effect+of+physical+exercise+in+real-world+settings+on+executive+function+of+atypical+children%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Shi&amp;pid=%3Cauthor%3EShi+P%3C%2Fauthor%3E%3CAN%3E37873578%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cch.13182?download=true
VL  - 24
ER  -
TY  - JOUR
AB  - **Background:** 
A considerable number of published reviews have addressed the effects of physical exercise on mental health, cognitive function, or attention-deficit hyperactivity (ADHD) symptoms as outcomes in children and adolescents with ADHD. Their findings have often conflicted, therefore, there is an urgent need to synthesise a hierarchy of the evidence and examine the credibility of previous meta-analyses. To establish the robustness of these findings, we conducted an additional meta-analysis on a number of individual studies that were not covered in previous reviews but were suitable for inclusion in our own study. 

**Methods:** 
Three reviewers independently searched Web of Science, Psych INFO, Embase, Cochrane Library, PubMed, SPORTDiscus, and Cumulative Index to Nursing and Allied Health Literature (CINAHL) for meta-analyses published between database inceptions to December 1, 2022. The individual studies were also screened from 1 January 2015 to 1 December 2022. We included meta-analyses and eligible individual studies that addressed the effects of exercise on at least one outcome of mental health, cognitive function, or ADHD symptoms in children and adolescents with ADHD. We excluded systematic reviews and articles that lacked sufficient data for a meaningful second analysis. The effect estimates (Hedges&#039; g), 95% confidence interval (95% CI), 95% prediction interval (95% PI), small study effects, and excess significance bias were calculated. Finally, we categorised the meta-analyses based on the credibility of the evidence criteria and their quality using a Measurement Tool to Assess Systematic Reviews 2 checklist. This umbrella review was registered with PROSPERO, CRD42022361331. 

**Findings:** 
Of 181 listed review articles and 60 individual papers, 10 reviews and 12 individual articles were included in the meta-analyses. This yielded 37 meta-analyses based on 106 study estimates. Evidence was highly suggestive for the effectiveness of exercise (class II) for improving inattention (G = 0.92, 95% CI: 0.44-1.39, 95%), inhibitory control (G = 0.82, 95% CI: 0.52-1.13), and cognitive flexibility (G = 0.52, 95% CI: 0.32-0.72). However, evidence for the effectiveness of exercise on emotional, social, and working memory outcomes was weak, and these results were not significant for hyperactivity and behavioural functioning. Interpretation: Improvement of cognitive flexibility, inhibitory control, and inattention in children and adolescents with ADHD was highly suggested by exercise interventions. However, results were weak for other outcomes (emotional functioning, social functioning, and working memory). Further high-quality randomised controlled trials are, therefore, warranted to determine the effectiveness of exercise on weak outcomes. 

**Funding:** None.
AN  - 37599910
AU  - Dastamooz,
AU  - S.
AU  - Sadeghi-Bahmani,
AU  - D.
AU  - Farahani,
AU  - M.
AU  - H.
AU  - D.
AU  - Wong,
AU  - S.
AU  - H.
AU  - S.
AU  - Yam,
AU  - J.
AU  - C.
AU  - S.
AU  - Tham,
AU  - C.
AU  - C.
AU  - Y.
AU  - Sit,
AU  - C.
AU  - H.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.eclinm.2023.102137
L1  - internal-pdf://2145990036/Dastamooz-2023-The efficacy of physical exerci.pdf
PY  - 2023
SP  - 102137
T2  - EClinicalMedicine
TI  - The efficacy of physical exercise interventions on mental health, cognitive function, and ADHD symptoms in children and adolescents with ADHD: an umbrella review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37599910
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432969/pdf/main.pdf
VL  - 62
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Medical clowning has been proven effective in reducing pain, anxiety, and stress in many sporadic, usually small-scale studies. Our meta-analysis aims to evaluate the efficiency of medical clowns in reducing pain and anxiety in hospitalized pediatric patients and their parents in different medical fields. 

METHODS: 
A thorough literature search was conducted from different databases, and only randomized controlled trials (RCTs) were included with children aged 0 to 18 years old. A total of 18 studies were included, and statistical analysis was performed on the combined data. 

RESULTS: 
A total of 912 children (14 studies) showed significantly reduced anxiety when procedures were performed with a medical clown compared with the controls (- 0.76 on anxiety score, P &lt; 0.001). Preoperative anxiety was lower in 512 children (nine studies) with clown interventions than in the controls (- 0.78, P &lt; 0.001). The pain scale was completed by 338 participants (six studies), indicating a trend toward reduced pain during procedures performed while the clown was acting compared to controls (- 0.49, P = 0.06). In addition, medical clown significantly (- 0.52, P = 0.001) reduced parental anxiety in 489 participants in ten studies; in six of the ten studies, with a total of 380 participants, medical clown significantly reduced parental preoperative anxiety (P = 0.02). 

CONCLUSION: 
Medical clowns have substantial positive and beneficial effects on reducing stress and anxiety in children and their families in various circumstances in pediatrics. Copyright &copy; 2023. The Author(s).
AN  - 37058203
AU  - Kasem
AU  - Ali
AU  - Sliman,
AU  - R.
AU  - Meiri,
AU  - N.
AU  - Pillar,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12519-023-00720-y
L1  - internal-pdf://1761746643/Kasem Ali Slima-2023-Medical clowning in hospi.pdf
PY  - 2023
SP  - 14
T2  - World Journal of Pediatrics
TI  - Medical clowning in hospitalized children: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37058203
UR  - https://link.springer.com/content/pdf/10.1007/s12519-023-00720-y.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - IMPORTANCE: The Cochrane review (2016) on kangaroo mother care (KMC) demonstrated a significant reduction in the risk of mortality in low birth weight infants. New evidence from large multi-centre randomised trials has been available since its publication. OBJECTIVE: Our systematic review compared the effects of KMC vs conventional care and early (ie, within 24 hours of birth) vs late initiation of KMC on critical outcomes such as neonatal mortality. 

METHODS: Eight electronic databases, including PubMed&lt;sup&gt; R&lt;/sup&gt;, Embase, and Cochrane CENTRAL, from inception until March 2022, were searched. All randomised trials comparing KMC vs conventional care or early vs late initiation of KMC in low birth weight or preterm infants were included. 

DATA EXTRACTION AND SYNTHESIS: The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered with PROSPERO. 

MAIN OUTCOMES AND MEASURES: The primary outcome was mortality during birth hospitalization or 28 days of life. Other outcomes included severe infection, hypothermia, exclusive breastfeeding rates, and neurodevelopmental impairment. Results were pooled using fixed-effect and random-effects meta-analyses in RevMan 5.4 and Stata 15.1 (StataCorp, College Station, TX). 

RESULTS: In total, 31 trials with 15 559 infants were included in the review; 27 studies compared KMC with conventional care, while four compared early vs late initiation of KMC. Compared with conventional care, KMC reduces the risks of mortality (relative risk (RR) 0.68; 95% confidence interval (CI) 0.53 to 0.86; 11 trials, 10 505 infants; high certainty evidence) during birth hospitalisation or 28 days of age and probably reduces severe infection until the latest follow-up (RR 0.85, 95% CI 0.79 to 0.92; nine trials; moderate certainty evidence). On subgroup analysis, the reduction in mortality was noted irrespective of gestational age or weight at enrolment, time of initiation, and place of initiation of KMC (hospital or community); the mortality benefits were greater when the daily duration of KMC was at least 8 hours per day than with shorter-duration KMC. Studies comparing early vs late-initiated KMC demonstrated a reduction in neonatal mortality (RR 0.77, 95% CI 0.66 to 0.91; three trials, 3693 infants; high certainty evidence) and a probable decrease in clinical sepsis until 28-days (RR 0.85, 95% CI 0.76 to 0.96; two trials; low certainty evidence) following early initiation of KMC. 

CONCLUSIONS AND RELEVANCE: The review provides updated evidence on the effects of KMC on mortality and other critical outcomes in preterm and low birth weight infants. The findings suggest that KMC should preferably be initiated within 24 hours of birth and provided for at least 8 hours daily.
AN  - 37277198
AU  - Sivanandan,
AU  - S.
AU  - Sankar,
AU  - M.
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1136/bmjgh-2022-010728
L1  - internal-pdf://1577051417/Sivanandan-2023-Kangaroo mother care for prete.pdf
PY  - 2023
SP  - 06
T2  - Bmj Global Health
TI  - Kangaroo mother care for preterm or low birth weight infants: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37277198
UR  - https://gh.bmj.com/content/bmjgh/8/6/e010728.full.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - BACKGROUND: 
The aim of this study was to assess the efficiency and safety of acupuncture in core symptomatic improvement of children with autism spectrum disorder (ASD). METHODS: We searched the following databases: Cochrane Library, PubMed, Embase, Medline, China National Knowledge Infrastructure (CNKI), Wanfang, Chinese Science and Technology Periodical (VIP) and Chinese Biological Medicine (CBM), from 1 January 2012 to 25 September 2022. The Autism Behavior Checklist (ABC), Childhood Autism Rating Scale (CARS), and Autism Treatment Evaluation Checklist (ATEC) were adopted as outcome indicators. Three reviewers independently assessed the risk of bias (ROB) and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE)assessment. Utilizing Review Manager (RevMan) 5.3 and Stata 12.0, data were analyzed. 

RESULTS: A total of 38 trials were included, and 2862 participants participated in qualitative synthesis and meta-analysis. Only 1 trial was assessed as having a low ROB, and 37 trials were assessed as having an overall high ROB. The quality of evidence for most indicators were considered very low by the GRADE criteria. The results showed that acupuncture groups might have a higher clinical effective rate than nonacupuncture groups (relative risk [RR] = 1.33,95% confidence interval [CI] = 1.25-1.41; heterogeneity: x2=18.15, P = .64, I2 = 0%). Regarding changes in ABC scores, the acupuncture groups might exhibit greater decrease than nonacupuncture groups (MMD = -6.06, 95%CI = -7.25 to -4.87, P &lt; .00001; heterogeneity: x2 =73.37, P = .03, I2 = 77%). In terms of changes in CARS score, acupuncture group may benefit more than nonacupuncture group (MMD = -3.93, 95%CI = 4.90 to -2.95, P &lt; .00001; heterogeneity: x2=234.47, P &lt; .00001, I2 = 90%). Additionally, in terms of ATEC score, acupuncture groups showed more benefit than nonacupuncture groups (MMD = -10.24, 95%CI = -13.09 to -7.38, P &lt; .00001; heterogeneity: x2=45.74, P = .04, I2 = 85%). Both subgroup analysis and sensitivity analysis are existing heterogeneity. Only 1 RCT study involved adverse events with mild symptoms that did not interfere with treatment and evaluation. 

CONCLUSION: Children with ASD may benefit from acupuncture because of its effectiveness and safety. Nevertheless, given the low quality of the evidence for the assessed outcomes and the high ROB of analyzed trials, the results should be regarded with caution.
AN  - 36827010
AU  - Lun,
AU  - T.
AU  - Lin,
AU  - S.
AU  - Chen,
AU  - Y.
AU  - Zhao,
AU  - Y.
AU  - Wang,
AU  - D.
AU  - Li,
AU  - L.
AU  - Yu,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1097/MD.0000000000033079
L1  - internal-pdf://2011301429/Acupuncture_for_children_with_autism_spectrum.pdf
PY  - 2023
SP  - e33079
T2  - Medicine
TI  - Acupuncture for children with autism spectrum disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36827010
VL  - 102
ER  -
TY  - JOUR
AB  - Virtual reality (VR) shows great potential in treating and managing various mental health conditions. This includes using VR for training or rehabilitation purposes. For example, VR is being used to improve cognitive functioning (e.g. attention) among children with attention/deficit-hyperactivity disorder (ADHD). The aim of the current review and meta-analysis is to evaluate the effectiveness of immersive VR-based interventions for improving cognitive deficits in children with ADHD, to investigate potential moderators of the effect size and assess treatment adherence and safety. 

The meta-analysis included seven randomised controlled trials (RCTs) of children with ADHD comparing immersive VR-based interventions with controls (e.g. waiting list, medication, psychotherapy, cognitive training, neurofeedback and hemoencephalographic biofeedback) on measures of cognition. 

Results indicated large effect sizes in favour of VR-based interventions on outcomes of global cognitive functioning, attention, and memory. Neither intervention length nor participant age moderated the effect size of global cognitive functioning. Control group type (active vs passive control group), ADHD diagnostic status (formal vs. informal) and novelty of VR technology were not significant moderators of the effect size of global cognitive functioning. Treatment adherence was similar across groups and there were no adverse effects. Results should be cautiously interpreted given the poor quality of included studies and small sample.
AN  - 36845650
AU  - Corrigan,
AU  - N.
AU  - Pasarelu,
AU  - C.
AU  - R.
AU  - Voinescu,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10055-023-00768-1
L1  - internal-pdf://1418376523/Corrigan-2023-Immersive virtual reality for im.pdf
PY  - 2023
SP  - 1-20
T2  - Virtual Reality
TI  - Immersive virtual reality for improving cognitive deficits in children with ADHD: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36845650
UR  - https://link.springer.com/content/pdf/10.1007/s10055-023-00768-1.pdf
ER  -
TY  - JOUR
AB  - INTRODUCTION: Many nonregulatory interventions targeting children and youth have been implemented at three levels: directed at the individual (e.g., interactive video games), delivered to students at school (e.g., campus bans), and launched in the community (e.g., mass media campaigns). This systematic review aims to synthesize the evidence on the effectiveness of interventions aimed at preventing e-cigarette initiation among children and youth.

METHODS: MEDLINE, CINAHL, Embase, APA PsycINFO, and Web of Science Core Collection were searched for papers published between January 1, 2004 and September 1, 2022 that reported more than one outcome on vaping prevention among individuals aged less than 21-years-old: vaping prevalence/incidence, initiation intentions, knowledge/attitudes, and other tobacco product use prevalence/initiation intentions. Interventions were at the individual, school, or community level. The risk of bias was assessed using ROBINS-I and RoB 1.

RESULTS: Thirty-nine publications met the eligibility criteria. Fourteen individually-based (4 parental monitoring, 3 video games, 2 text messages, 3 graphic message themes, 2 healthcare), 19 school-based (14 educational and skill interventions, 5 vape-free policies/bans), and 6 community-based (3 social media, 3 mass media campaigns) interventions were reported. E-cigarette initiation prevention was observed with high perceived parental monitoring; however, the cross-sectional study designs precluded causal claims. There was promising but limited evidence that social-emotional skills curricula and peer leader programming prevented vaping initiation.

DISCUSSION: Some individual- and school-based interventions showed promise for preventing e-cigarette initiation among children and youth.
AD  - Mylocopos, Genevieve. Center for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada; Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.Wennberg, Erica. Center for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.Reiter, Anna. Center for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada; Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.Hebert-Losier, Andrea. Center for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada.Filion, Kristian B. Center for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada; Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada; Departments of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada.Windle, Sarah B. Departments of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada.Gore, Genevieve. Schulich Library of Physical Sciences, Life Sciences, and Engineering, McGill University, Montreal, QC, Canada.O&#039;Loughlin, Jennifer L. Department of Social and Preventive Medicine, Universite de Montreal, Montreal, QC, Canada; Centre de recherche du Centre hospitalier de l&#039;Universite de Montreal, Montreal, QC, Canada.Grad, Roland. Lady Davis Institute, Jewish General Hospital, Montreal, QC, Canada; Department of Family Medicine, McGill University, Montreal, QC, Canada.Eisenberg, Mark J. Center for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada; Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada; Departments of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada; Division of Cardiology, Jewish General Hospital, McGill University, Montreal, QC, Canada. Electronic address: mark.eisenberg@mcgill.ca.
AN  - 37802308
AU  - Mylocopos,
AU  - G.
AU  - Wennberg,
AU  - E.
AU  - Reiter,
AU  - A.
AU  - Hebert-Losier,
AU  - A.
AU  - Filion,
AU  - K.
AU  - B.
AU  - Windle,
AU  - S.
AU  - B.
AU  - Gore,
AU  - G.
AU  - O&#039;Loughlin,
AU  - J.
AU  - L.
AU  - Grad,
AU  - R.
AU  - Eisenberg,
AU  - M.
AU  - J.
DA  - Oct 05
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.amepre.2023.09.028
DP  - Ovid Technologies
J2  - Am J Prev Med
L1  - internal-pdf://2832816322/PIIS0749379723003896.cleaned.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingOctMylocopos, GenevieveWennberg, EricaReiter, AnnaHebert-Losier, AndreaFilion, Kristian BWindle, Sarah BGore, GenevieveO&#039;Loughlin, Jennifer LGrad, RolandEisenberg, Mark JS0749-3797(23)00389-6
PY  - 2023
SP  - 05
T2  - American Journal of Preventive Medicine
TI  - Interventions for Preventing E-Cigarette Use Among Children and Youth: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37802308
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37802308&amp;id=doi:10.1016%2Fj.amepre.2023.09.028&amp;issn=0749-3797&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2023&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=Interventions+for+Preventing+E-Cigarette+Use+Among+Children+and+Youth%3A+A+Systematic+Review.&amp;aulast=Mylocopos&amp;pid=%3Cauthor%3EMylocopos+G%3C%2Fauthor%3E%3CAN%3E37802308%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/pii/S0749379723003896?via%3Dihub
VL  - 05
ER  -
TY  - JOUR
AB  - **Objective:** 
This meta-analysis of randomized clinical trials (RCTs) was conducted to explore the therapeutic effects, tolerability and safety of repetitive transcranial magnetic stimulation (rTMS) as an adjunct treatment in adolescents with first-episode major depressive disorder (FE-MDD). 

**Methods:** 
RCTs examining the efficacy, tolerability and safety of adjunctive rTMS for adolescents with FE-MDD were included. Data were extracted by three independent authors and synthesized using RevMan 5.3 software with a random effects model. 

**Results:** 
A total of six RCTs involving 562 adolescents with FE-MDD were included. Adjunctive rTMS was superior in improving depressive symptoms over the control group [standardized mean difference (SMD) = -1.50, 95% confidence interval (CI): -2.16, -0.84; I&lt;sup&gt;2&lt;/sup&gt; = 89%, p &lt; 0.00001] in adolescents with FE-MDD. A sensitivity analysis and two subgroup analyses also confirmed the significant findings. Adolescents with FE-MDD treated with rTMS had significantly greater response [risk ratio (RR) = 1.35, 95% CI: 1.04, 1.76; I&lt;sup&gt;2&lt;/sup&gt; = 56%, p = 0.03] and remission (RR = 1.35, 95% CI: 1.03, 1.77; I&lt;sup&gt;2&lt;/sup&gt; = 0%, p = 0.03) over the control group. All-cause discontinuations were similar between the two groups (RR = 0.79, 95% CI: 0.32, 1.93; I&lt;sup&gt;2&lt;/sup&gt; = 0%, p = 0.60). No significant differences were found regarding adverse events, including headache, loss of appetite, dizziness and nausea (p = 0.14-0.82). Four out of six RCTs (66.7%), showed that adjunctive rTMS was more efficacious over the control group in improving neurocognitive function (all p &lt; 0.05). 

**Conclusion:** 
Adjunctive rTMS appears to be a beneficial strategy in improving depressive symptoms and neurocognitive function in adolescents with FE-MDD. Higher quality RCTs with larger sample sizes and longer follow-up periods are warranted in the future.
AN  - 37593451
AU  - Sun,
AU  - C.
AU  - H.
AU  - Mai,
AU  - J.
AU  - X.
AU  - Shi,
AU  - Z.
AU  - M.
AU  - Zheng,
AU  - W.
AU  - Jiang,
AU  - W.
AU  - L.
AU  - Li,
AU  - Z.
AU  - Z.
AU  - Huang,
AU  - X.
AU  - B.
AU  - Yang,
AU  - X.
AU  - H.
AU  - Zheng,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2023.1200738
L1  - internal-pdf://2541530483/Sun_2023.pdf
PY  - 2023
SP  - 1200738
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Adjunctive repetitive transcranial magnetic stimulation for adolescents with first-episode major depressive disorder: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37593451
VL  - 14
ER  -
TY  - JOUR
AB  - **Objective:** 
To assess the overall effectiveness of non-pharmacological interventions on internet addiction (IA) in youth. 

**Method:** 
Randomized controlled trials (RCTs) published from their inception to April 1, 2023 were searched in Cochrane, Embase, Medline, Web of Science, China National Knowledge Infrastructure, China Science and Technology Journal Database, Chinese BioMedical Literature Database, and WanFang Data. Two reviewers independently extracted data and evaluated bias using the Cochrane Risk of Bias tool. 

**Results:** 
Sixty-six studies performed from 2007 to 2023, with a total of 4,385 participants, were identified. The NPIs included group counseling, cognitive behavioral therapy, sports intervention, combined interventions, eHealth, educational intervention, positive psychology intervention, sand play intervention, and electrotherapy. The results revealed that NPIs significantly reduced IA levels (standardized mean difference, SMD: -2.01, 95% confidence interval, CI: -2.29 to -1.73, I&lt;sup&gt;2&lt;/sup&gt; = 93.0%), anxiety levels (SMD: -1.07, 95%CI: -1.41 to -0.73, I&lt;sup&gt;2&lt;/sup&gt; = 72.4%), depression levels (SMD: -1.11, 95%CI: -1.52 to -0.7, I&lt;sup&gt;2&lt;/sup&gt; = 84.3%), and SCL-90 (SMD: -0.75, 95%CI: -0.97 to -0.54, I&lt;sup&gt;2&lt;/sup&gt; = 27.7%). Subgroup analysis stratified by intervention measure showed that cognitive behavioral therapy, group counseling, sports intervention, combined intervention, educational intervention, positive psychology intervention, sandplay intervention, and mobile health were all effective in relieving symptoms of IA except electrotherapy. 

**Conclusion:** 
NPIs appear to be effective in the treatment of IA in youth, which would act as an alternative treatment of IA. Further studies with larger sample sizes and robust designs are needed.
AN  - 38274427
AU  - Jiang,
AU  - Y.
AU  - S.
AU  - Liu,
AU  - T.
AU  - H.
AU  - Qin,
AU  - D.
AU  - Wang,
AU  - Z.
AU  - P.
AU  - He,
AU  - X.
AU  - Y.
AU  - Chen,
AU  - Y.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2023.1327200
L1  - internal-pdf://2901835605/Jiang-2023-Effects of non-pharmacological inte.pdf
PY  - 2023
SP  - 1327200
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Effects of non-pharmacological interventions on youth with internet addiction: a systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=38274427
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/1327200/pubmed-zip/.versions/1/.package-entries/fpsyt-14-1327200/fpsyt-14-1327200.pdf?sv=2018-03-28&amp;sr=b&amp;sig=o1tT5xutlie9ZtTjbaEKhip9AMzreKHrDJNdPIZznMU%3D&amp;se=2024-02-06T12%3A05%3A57Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyt-14-1327200.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - PURPOSE: To describe allied health and educational interventions and their effectiveness for children and adolescents with fetal alcohol spectrum disorder (FASD). To appraise the quality and strength of studies.

METHODS: Electronic databases were searched between 2005 and March 2022, identifying non-pharmacological studies supporting function, activity, or participation for FASD participants aged 5-18 years using any quantitative research design. Outcomes were coded using International Classification of Functioning, Disability and Health, family of Participation Related Constructs and behaviour categories. Multi-level random-effects meta-analysis examined intervention effects. Study methodological quality was evaluated using Cochrane risk of bias tools, RoBiNT, AMSTAR 2 and NHMRC Hierarchy levels of evidence. Certainty of findings were synthesised using GRADE approach.

RESULTS: The systematic review included 25 studies with 735 participants, 10 of which were analysed by meta-analysis. Body function and structure, activity, behaviour, and sense of self outcomes were pooled. A small, positive effect favouring interventions was found (g = 0.29, 95% CI = 0.15-0.43), however the GRADE certainty was rated as low. No participation outcomes were identified.

CONCLUSIONS: Some interventions targeting body function and structure, activity and behaviour outcomes were effective. Evidence of interventions that support children&#039;s and adolescent&#039;s participation as an outcome is lacking.
AU  - Hilly,
AU  - C.
AU  - Wilson,
AU  - P.
AU  - H.
AU  - Lucas,
AU  - B.
AU  - McGuckian,
AU  - T.
AU  - B.
AU  - Swanton,
AU  - R.
AU  - Froude,
AU  - E.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/09638288.2023.2207043
L1  - internal-pdf://0629767077/Hilly-2023-Effectiveness of interventions for.pdf
PY  - 2023
SP  - 1-26
T2  - Disability and Rehabilitation
TI  - Effectiveness of interventions for school-aged-children and adolescents with fetal alcohol spectrum disorder: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37158227
UR  - https://www.tandfonline.com/doi/pdf/10.1080/09638288.2023.2207043
ER  -
TY  - JOUR
AB  - **Objective:** 
To investigate the effect of kangaroo mother care for low-birth-weight and preterm infants on parents&#039; mental and physical health. 

**Methods:** 
The Cochrane Central Register of Controlled Trials, Cochrane Register of Studies Online, PubMed, Web of Science, Scopus and EMBASE databases were searched on 16 January 2023 for randomized and quasi-randomized trials on kangaroo mother care. Records identified were screened independently by two reviewers. Pooled relative risks (RRs) are reported for categorical variables, and standardized mean differences (SMDs) or mean differences are reported for continuous variables. Evidence quality was assessed using the GRADE approach. 

**Findings:** 
The search identified 30 studies involving 7719 preterm or low-birth-weight infants. There was high-certainty evidence that kangaroo mother care substantially reduced the risk of moderate-to-severe postpartum maternal depressive symptoms compared with no kangaroo mother care (RR: 0.76; 95% confidence interval, CI: 0.59 to 0.96). In addition, there was low-certainty evidence that kangaroo mother care reduced scores for maternal stress (SMD: -0.82; 95% CI: -1.32 to -0.32) and anxiety (SMD: -0.62; 95% CI: -1.01 to -0.23) and increased mother-infant attachment and bonding scores (SMD: 1.19; 95% CI: 0.27 to 2.10). Limited evidence indicated father-infant interactions may be improved, though no marked effect on paternal depression or stress was observed. No trial reported parental physical health outcomes. 

**Conclusion:** 
Kangaroo mother care for preterm and low-birth-weight infants was associated with less postpartum maternal depression, stress and anxiety and better mother-infant attachment and bonding. More research is required to evaluate effects on paternal health.
AN  - 37265678
AU  - Pathak,
AU  - B.
AU  - G.
AU  - Sinha,
AU  - B.
AU  - Sharma,
AU  - N.
AU  - Mazumder,
AU  - S.
AU  - Bhandari,
AU  - N.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.2471/BLT.22.288977
L1  - internal-pdf://3635732004/Pathak-2023-Effects of kangaroo mother care on.pdf
PY  - 2023
SP  - 391-402G
T2  - Bulletin of the World Health Organization
TI  - Effects of kangaroo mother care on maternal and paternal health: systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37265678
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10225947/pdf/BLT.22.288977.pdf
VL  - 101
ER  -
TY  - JOUR
AB  - There is vast empirical evidence showing that juvenile delinquency is associated with delays in moral development, including moral judgment, empathy, and self-conscious emotions (guilt and shame). Consequently, interventions have been developed that target moral development of juvenile delinquents to reduce criminal offense recidivism. However, a comprehensive synthesis of studies examining the effectiveness of these interventions was not yet available. The present meta-analysis of (quasi-)experimental research therefore examined the effects of interventions that target moral development of youth engaged in delinquent behavior. Interventions that targeted moral judgment (11 studies and 17 effect sizes) showed a significant and small-to-medium effect on moral judgment (d = 0.39), with intervention type as a significant moderator, but no significant effect on recidivism (d = 0.03; 11 studies and 40 effect sizes). No (quasi-)experimental studies were found that targeted guilt and shame in juvenile offenders, and an insufficient number of studies (i.e., only two) were found to conduct a meta-analysis of interventions that target empathy. The discussion focuses on potential ways to improve moral development interventions for youth engaged in delinquent behavior, and provides suggestions for future research.
AU  - Heynen,
AU  - E.
AU  - Hoogsteder,
AU  - L.
AU  - van
AU  - Vugt,
AU  - E.
AU  - Schalkwijk,
AU  - F.
AU  - Stams,
AU  - G.-J.
AU  - Assink,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/0306624X231172648
L1  - internal-pdf://3291054449/heynen-et-al-2023-effectiveness-of-moral-devel.pdf
PY  - 2023
SP  - 306624X231172648
T2  - International journal of offender therapy and comparative criminology
TI  - Effectiveness of Moral Developmental Interventions for Youth Engaged in Delinquent Behavior: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37212305
UR  - https://journals.sagepub.com/doi/10.1177/0306624X231172648
ER  -
TY  - JOUR
AB  - Gender differences in mental health emerge as early as in childhood and adolescence, highlighting the potential need for gender-specific child and adolescent mental health care. However, it is unclear how gender-specific child and adolescent mental health care is implemented and whether its&#039; approaches are useful. Therefore, this study reviews gender-specific interventions and their effectiveness for child and adolescent mental health.

Five databases were searched for articles published between 2000 and 2021.

In total, 43 studies were included. Most interventions were conducted in school (n = 15) or community settings (n = 8). Substance-related disorders (n = 13) and eating disorders (n = 12) were addressed most frequently. Most interventions targeted girls (n = 31). Various gender-specific aspects were considered, including gender-specific risk and protective factors (n = 35) and needs (n = 35).

Although most interventions yielded significant improvements in mental health outcomes (n = 32), only few studies reported medium or large effect sizes (n = 13). Additionally, there was a lack of strong causal evidence derived from randomized controlled trials, calling for more rigorous trials in the research field. Nevertheless, our findings indicate that gender-specific mental health care can be a promising approach to meet gender-specific mental health needs.
AN  - 36849848
AU  - Herrmann,
AU  - L.
AU  - Reiss,
AU  - F.
AU  - Becker-Hebly,
AU  - I.
AU  - Baldus,
AU  - C.
AU  - Gilbert,
AU  - M.
AU  - Stadler,
AU  - G.
AU  - Kaman,
AU  - A.
AU  - Graumann,
AU  - L.
AU  - Ravens-Sieberer,
AU  - U.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10578-023-01506-z
L1  - internal-pdf://2654452784/Herrmann-2023-Systematic Review of Gender-Spec.pdf
PY  - 2023
SP  - 27
T2  - Child Psychiatry &amp; Human Development
TI  - Systematic Review of Gender-Specific Child and Adolescent Mental Health Care
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36849848
UR  - https://link.springer.com/content/pdf/10.1007/s10578-023-01506-z.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - Anxiety disorders are highly prevalent in children and adolescents. The associated functional limitations and the negative psychological consequen-ces have led to increased research into effective psychological interventions. What is missing, however, is a comprehensive review of the literature addressing the effectiveness of these treatments for specific disorders. A systematic review of systematic reviews and meta-analyses evaluating the effectiveness of psychological treatments for specific anxiety disorders in children and adolescents was performed. The study followed PRISMA guidelines. Four bibliographic databases were searched: MEDLINE (PubMed), PsycINFO, Web of Science (Core Collection), and The Cochrane Library. Two authors independently screened the articles by title, abstract, and full-text, according to established inclusion and exclusion criteria. Two independent authors evaluated the methodological quality of the included reviews using AMSTAR-2. Five records were included in this syste-matic review. Four studies included children and adolescents with specific phobias, generalized anxiety disorder, and separation anxiety disorder and one focused solely on nocturnal fears. Cognitive behavioral therapy-based interventions have been shown to be effective for the treatment of these diagnoses in both short and long term. The methodological quality of the included studies was classified as critically low. Cognitive behavioral interventions are effective in treating specific phobias, generalized anxiety disorder, and separation anxiety disorder and nighttime fears in children and adolescents. The improvement of the methodological quality and the need for further studies focusing on the effectiveness of treatments for specific disorders are discussed.
AN  - WOS:000975493000005
AU  - Galan-Luque,
AU  - T.
AU  - Serrano-Ortiz,
AU  - M.
AU  - Orgiles,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.21134/rpcna.2023.10.1.3
L1  - internal-pdf://2342244800/Galan-Luque-2023-Effectiveness of psychologica.pdf
PY  - 2023
SP  - 31-41
T2  - Revista De Psicologia Clinica Con Ninos Y Adolescentes
TI  - Effectiveness of psychological interventions for child and adolescent specific anxiety disorders: A systematic review of systematic reviews and meta-analyses
UR  - &lt;Go to ISI&gt;://WOS:000975493000005
VL  - 10
ER  -
TY  - JOUR
AB  - The effect of vitamin D supplementation on individuals with autism spectrum disorder (ASD) is inconclusive. We aimed to conduct a meta-analysis of the available randomized controlled trials (RCTs) to explore whether vitamin D supplementation can improve core symptoms and coexisting conditions in children with ASD. Data were obtained by searching the PubMed, Embase, Web of Science, CINAHL and Cochrane Library databases up to February 2022 following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Using a random-effects model, mean differences with 95% confidence intervals (CIs) were calculated through a meta-analysis. There were eight RCTs with 266 children with ASD in the present review, among which six RCTs were included in the meta-analysis. Children who received vitamin D supplementation showed a significant improvement in stereotypical behavior scores (pooled mean difference (MD): -1.39; 95% CI: -2.7, -0.07; P = 0.04) with low heterogeneity (I2 = 34%), and there was a trend toward decreased total scores on the Social Responsiveness Scale (SRS) and Childhood Autism Rating Scale (CARS, P = 0.05); however, there were no other significant differences in the core symptoms of ASD and coexisting conditions between groups as measured by the Aberrant Behavior Checklist (ABC). Vitamin D supplementation appears to improve stereotypical behaviors but does not improve other core symptoms and coexisting conditions. Further randomized controlled trials with large sample sizes and individualized doses are needed.
AU  - Zhang,
AU  - M.
AU  - Wu,
AU  - Y.
AU  - Lu,
AU  - Z.
AU  - Song,
AU  - M.
AU  - Huang,
AU  - X.
AU  - Mi,
AU  - L.
AU  - Yang,
AU  - J.
AU  - Cui,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.9758/cpn.2023.21.2.240
L1  - internal-pdf://3244062997/Zhang-2023-Effects of Vitamin D Supplementatio.pdf
PY  - 2023
SP  - 240-251
T2  - Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
TI  - Effects of Vitamin D Supplementation on Children with Autism Spectrum Disorder: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=pmnm&amp;NEWS=N&amp;AN=37119216
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10157012/pdf/cpn-21-2-240.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - **Background:** 
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that commonly occurs in childhood. The aim of this meta-analysis was to summarize the available evidence for the efficacy of digital therapeutics in children and adolescents with ADHD. 

**Methods:** 
We searched the MEDLINE, EMBASE, Cochrane Library (Cochrane Database of Systematic Reviews), and Web of Science (science and social science citation index) databases for relevant studies and used Stata 15.0 software to carry out the meta-analysis. 

**Results:** 
A total of 31 studies involving 2169 participants (1665 boys and 504 girls) aged 4-17 years old were included in the final analysis. The meta-analysis results showed that digital interventions improved the symptoms of inattention with an effect value of -0.20 (95% confidence interval [CI] -0.36, -0.04) and decreased the continuous performance task (CPT) reaction time (effect, -0.40, 95% CI -0.73, -0.07) in ADHD patients. The score for impulsive hyperactivity was slightly decreased (effect, -0.07, 95% CI -0.23, 0.09). Moreover, executive function was improved (effect, 0.71, 95% CI 0.37, 1.04). The capability of working memory appeared to be increased (effect, 0.48, 95% CI 0.21, 0.76) between the two groups. Visual appraisal of the sensitivity analysis suggested the absence of heterogeneity, and no obvious publication bias was detected. 

**Discussion:** 
Based on the existing literature evidence, we conclude that digital therapy can be a promising therapeutic strategy for ADHD patients.
AN  - 37260755
AU  - He,
AU  - F.
AU  - Qi,
AU  - Y.
AU  - Zhou,
AU  - Y.
AU  - Cao,
AU  - A.
AU  - Yue,
AU  - X.
AU  - Fang,
AU  - S.
AU  - Zheng,
AU  - Y.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyt.2023.1054831
L1  - internal-pdf://1459082601/pdf.cleaned (3).pdf
PY  - 2023
SP  - 1054831
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Meta-analysis of the efficacy of digital therapies in children with attention-deficit hyperactivity disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37260755
VL  - 14
ER  -
TY  - JOUR
AB  - **Background**
Conduct problems are a range of disruptive behaviours in childhood that are associated with long‐term adverse outcomes in adolescence and adulthood, including antisocial behaviour, substance misuse, and poor academic achievement. Children with conduct problems can vary according to age of onset, comorbidities, and environmental factors, and it has been suggested that certain groups of children may have different treatment outcomes. Therefore, it is important to assess the extent to which personalised interventions for different groups of children with conduct problems may affect outcomes. To our knowledge, this is the first review to systematically identify and appraise the effectiveness of personalised interventions, adapted, or developed, for prespecified subgroups of children with conduct problems.

**Objectives**
To assess whether personalised interventions, adapted or developed for subgroups of children with conduct problems are effective in improving outcomes.

**Search methods**
We used standard, extensive Cochrane search methods. The latest search was 1 February 2022.

**Selection criteria**
We included randomised controlled trials (RCTs), in any setting, in children (aged two to 12 years) with conduct problems and within a prespecified subgroup, comparing a personalised intervention with a non‐personalised intervention, waitlist control, or treatment as usual. Personalised interventions included adaptations to standard practice, such as parent‐training programmes; other recommended interventions for children with conduct problems; or interventions developed specifically to target subgroups of children with conduct problems. We excluded non‐personalised and non‐psychological interventions (e.g. pharmacological or dietary intervention). Prespecified subgroups of children with conduct problems, however defined, were eligible for inclusion.

**Data collection and analysis**
We used standard Cochrane methods. Our primary outcomes were 1. child conduct problems or disruptive behaviour and 2. adverse events. Our secondary outcomes were 3. personalised treatment outcomes relevant to each subgroup, 4. parenting skills and knowledge, 5. family functioning, engagement and decreased dropout, and 6. educational outcomes. We used GRADE to assess the certainty of the evidence.

**Main results**

Improvement in child conduct problems and disruptive behaviour
Compared with a non-personalised intervention, a personalised intervention may result in a slight improvement in child conduct problems or disruptive behaviour measured using the Eyberg Child Behavior Inventory (ECBI) Problem subscale in the short term (mean difference (MD) &minus;3.04, 95% confidence interval (CI) &minus;6.06 to &minus;0.02; 6 studies, 278 participants; P = 0.05), but may have little to no effect on improving child conduct problems or disruptive behaviour measured by the ECBI Intensity subscale (MD &minus;6.25, 95% CI &minus;16.66 to 4.15; 6 studies, 278 participants; P = 0.24), or the Externalising subscale of the Child Behaviour Checklist (CBCL) (MD &minus;2.19, 95% CI &minus;6.97 to 2.59; 3 studies, 189 participants, P = 0.37) in the short term. We graded the certainty of evidence as very low for all three outcomes, meaning any estimate of effect is very uncertain.

Personalised treatment outcomes, relevant to each subgroup
Although six studies reported personalised treatment outcomes, relevant to each subgroup, we were unable to pool the data due to differences between the measures used in the studies and the heterogeneity this would produce in analysis. The results for this outcome were inconclusive.

Parenting skills and knowledge
Although seven studies reported parenting skills and knowledge, we were unable to pool the data due to differences between the measures used in the studies and the heterogeneity this would produce in analysis. The results for this outcome were inconclusive.

Adverse events 
None of the trials reported monitoring adverse events. 

Summary of results
In summary, there is limited evidence that personalised intervention improves child conduct problems, personalised treatment outcomes, relevant to each subgroup, or parenting skills and knowledge compared with a non-personalised intervention. 

**Authors&#039; conclusions**
There is limited evidence for the effectiveness of personalised interventions for subgroups of children with conduct problems. The certainty of evidence for all outcomes was very low, meaning that we have very little confidence in the estimated effects and the true effects may be different to our findings, which will limit the relevance of our findings to clinical decisions. To overcome the limitations of the evidence, large-scale RCTs are needed to determine whether personalised interventions, adapted or developed, for subgroups of children with conduct problems are effective in improving outcomes. Consensus on the most appropriate measures to use in these studies is needed in order to facilitate cross-study comparisons. Persistent conduct problems predict a range of adverse long-term outcomes, so future research should investigate the medium- and long-term effects of personalised treatments. Studies are needed in low- and middle-income countries as well as studies recruiting children aged between nine and 12 years, as they were under-represented in the studies.
AU  - Lane,
AU  - C.
AU  - Hogg,
AU  - E.
AU  - Karwatowska,
AU  - L.
AU  - A.
AU  - French,
AU  - L.
AU  - Ranieri,
AU  - V.
AU  - F.
AU  - Jesnick,
AU  - L.
AU  - G.
AU  - D.
AU  - Roberts,
AU  - C.
AU  - Scott,
AU  - S.
AU  - Senior,
AU  - R.
AU  - Skinner,
AU  - G.
AU  - C.
AU  - M.
AU  - Kennedy,
AU  - E.
AU  - M.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD012746.pub2
L1  - internal-pdf://2585995728/Lane_et_al-2023-Cochrane_Database_of_Systemati.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Personalised interventions for subgroups of children with conduct problems
ER  -
TY  - JOUR
AB  - **Objectives**
To investigate whether psychosocial interventions for justice-involved youth are equally effective at reducing delinquent behavior for males and females.

**Methods**
We used meta-analysis to test for gender differences in intervention effects for justice-involved youth, including 10 randomized controlled trials that permitted assessment of gender-specific effect sizes.

**Results**
Findings show interventions were ineffective at reducing delinquency overall d = -0.006, p = .921. Moreover, there was no significant difference in recidivism outcomes by gender, Q = .071, p = .790; psychosocial interventions for justice-involved youth yielded null effects for males, d = 0.006, p = .933, and females, d = -.027, p = .785.

**Conclusions**
This study is the first meta-analysis focused on gender differences in intervention effects for justice-involved youth. Our findings suggest a need for further study to better understand what works for reducing recidivism among juvenile justice-involved males and females.
AN  - WOS:000978596400001
AU  - Galbraith,
AU  - K.
AU  - Huey,
AU  - S.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s11292-023-09567-9
L1  - internal-pdf://2089847402/Galbraith-2023-Gender differences in intervent.pdf
PY  - 2023
SP  - 13
T2  - Journal of Experimental Criminology
TI  - Gender differences in intervention effects on delinquency for justice-involved youth: A preliminary meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000978596400001
UR  - https://link.springer.com/content/pdf/10.1007/s11292-023-09567-9.pdf
ER  -
TY  - JOUR
AB  - **Background**
Preterm birth interferes with brain maturation, and subsequent clinical events and interventions may have additional deleterious effects. Music as therapy is offered increasingly in neonatal intensive care units aiming to improve health outcomes and quality of life for both preterm infants and the well‐being of their parents. Systematic reviews of mixed methodological quality have demonstrated ambiguous results for the efficacy of various types of auditory stimulation of preterm infants. A more comprehensive and rigorous systematic review is needed to address controversies arising from apparently conflicting studies and reviews.

**Objectives**
We assessed the overall efficacy of music and vocal interventions for physiological and neurodevelopmental outcomes in preterm infants (&lt; 37 weeks&#039; gestation) compared to standard care. In addition, we aimed to determine specific effects of various interventions for physiological, anthropometric, social‐emotional, neurodevelopmental short‐ and long‐term outcomes in the infants, parental well‐being, and bonding.

**Search methods**
We searched Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, CINAHL, PsycINFO, Web of Science, RILM Abstracts, and ERIC in November 2021; and Proquest Dissertations in February 2019. We searched the reference lists of related systematic reviews, and of studies selected for inclusion and clinical trial registries.

**Selection criteria**
We included parallel, and cluster‐randomised controlled trials with preterm infants &lt; 37 weeks` gestation during hospitalisation, and parents when they were involved in the intervention. Interventions were any music or vocal stimulation provided live or via a recording by a music therapist, a parent, or a healthcare professional compared to standard care. The intervention duration was greater than five minutes and needed to occur more than three times.

**Data collection and analysis**
Three review authors independently extracted data. We analysed the treatment effects of the individual trials using RevMan Web using a fixed‐effects model to combine the data. Where possible, we presented results in meta‐analyses using mean differences with 95% CI. We performed heterogeneity tests. When the I2 statistic was higher than 50%, we assessed the source of the heterogeneity by sensitivity and subgroup analyses. We used GRADE to assess the certainty of the evidence.

**Main results**
We included 25 trials recruiting 1532 infants and 691 parents (21 parallel‐group RCTs, four cross‐over RCTs). The infants gestational age at birth varied from 23 to 36 weeks, taking place in NICUs (level 1 to 3) around the world. Within the trials, the intervention varied widely in type, delivery, frequency, and duration. Music and voice were mainly characterised by calm, soft, musical parameters in lullaby style, often integrating the sung mother&#039;s voice live or recorded, defined as music therapy or music medicine. The general risk of bias in the included studies varied from low to high risk of bias.

Music and vocal interventions compared to standard care

Music/vocal interventions do not increase oxygen saturation in the infants during the intervention (mean difference (MD) 0.13, 95% CI ‐0.33 to 0.59; P = 0.59; 958 infants, 10 studies; high‐certainty evidence). Music and voice probably do not increase oxygen saturation post‐intervention either (MD 0.63, 95% CI ‐0.01 to 1.26; P = 0.05; 800 infants, 7 studies; moderate‐certainty evidence). The intervention may not increase infant development (Bayley Scales of Infant and Toddler Development (BSID)) with the cognitive composition score (MD 0.35, 95% CI ‐4.85 to 5.55; P = 0.90; 69 infants, 2 studies; low‐certainty evidence); the motor composition score (MD ‐0.17, 95% CI ‐5.45 to 5.11; P = 0.95; 69 infants, 2 studies; low‐certainty evidence); and the language composition score (MD 0.38, 95% CI ‐5.45 to 6.21; P = 0.90; 69 infants, 2 studies; low‐certainty evidence). Music therapy may not reduce parental state‐trait anxiety (MD ‐1.12, 95% CI ‐3.20 to 0.96; P = 0.29; 97 parents, 4 studies; low‐certainty evidence).

The intervention probably does not reduce respiratory rate during the intervention (MD 0.42, 95% CI ‐1.05 to 1.90; P = 0.57; 750 infants; 7 studies; moderate‐certainty evidence) and post‐intervention (MD 0.51, 95% CI ‐1.57 to 2.58; P = 0.63; 636 infants, 5 studies; moderate‐certainty evidence). However, music/vocal interventions probably reduce heart rates in preterm infants during the intervention (MD ‐1.38, 95% CI ‐2.63 to ‐0.12; P = 0.03; 1014 infants; 11 studies; moderate‐certainty evidence). This beneficial effect was even stronger after the intervention. Music/vocal interventions reduce heart rate post‐intervention (MD ‐3.80, 95% CI ‐5.05 to ‐2.55; P &lt; 0.00001; 903 infants, 9 studies; high‐certainty evidence) with wide CIs ranging from medium to large beneficial effects. Music therapy may not reduce postnatal depression (MD 0.50, 95% CI ‐1.80 to 2.81; P = 0.67; 67 participants; 2 studies; low‐certainty evidence). The evidence is very uncertain about the effect of music therapy on parental state anxiety (MD ‐0.15, 95% CI ‐2.72 to 2.41; P = 0.91; 87 parents, 3 studies; very low‐certainty evidence). We are uncertain about any further effects regarding all other secondary short‐ and long‐term outcomes on the infants, parental well‐being, and bonding/attachment. Two studies evaluated adverse effects as an explicit outcome of interest and reported no adverse effects from music and voice.

**Authors&#039; conclusions**
Music/vocal interventions do not increase oxygen saturation during and probably not after the intervention compared to standard care. The evidence suggests that music and voice do not increase infant development (BSID) or reduce parental state‐trait anxiety. The intervention probably does not reduce respiratory rate in preterm infants. However, music/vocal interventions probably reduce heart rates in preterm infants during the intervention, and this beneficial effect is even stronger after the intervention, demonstrating that music/vocal interventions reduce heart rates in preterm infants post‐intervention. We found no reports of adverse effects from music and voice. Due to low‐certainty evidence for all other outcomes, we could not draw any further conclusions regarding overall efficacy nor the possible impact of different intervention types, frequencies, or durations. Further research with more power, fewer risks of bias, and more sensitive and clinically relevant outcomes are needed.
AU  - Haslbeck,
AU  - F.
AU  - B.
AU  - Mueller,
AU  - K.
AU  - Karen,
AU  - T.
AU  - Loewy,
AU  - J.
AU  - Meerpohl,
AU  - J.
AU  - J.
AU  - Bassler,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013472.pub2
L1  - internal-pdf://2590702364/Haslbeck_et_al-2023-Cochrane_Database_of_Syste.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Musical and vocal interventions to improve neurodevelopmental outcomes for preterm infants
ER  -
TY  - JOUR
AB  - The implementation of universal school based Social-Emotional Learning (SEL) programs is increasing in Japanese schools with the aim of enhancing children&#039;s social-emotional skills and reducing mental health problems. However, there is a lack of meta-analyses evaluating the effectiveness of these programs in Japan that specifically include studies with control groups and examine program moderators. Conducting such a meta-analysis would be valuable for improving future implementations of SEL programs in Japan. The present meta-analysis analyzed 85 intervention studies with control groups to examine the effectiveness and moderators of universal school based SEL programs for Japanese children aged 5-18 years. The analysis indicates that these programs have a small overall effect (ES = 0.26), as well as small effects in improving social-emotional skills (ES = 0.24), attitude toward the self and others (ES = 0.30), positive social behavior (ES = 0.31), conduct problem (ES = 0.20), and emotional problem (ES = 0.22) at post-intervention among Japanese children. The analysis further revealed that publication type, number of participants, and school level of children moderated the overall effects of universal school based SEL programs, suggesting potential biases in effect sizes reported in peer-reviewed journals published by scientific societies, lower effectiveness for older children, and decreased effectiveness when programs are delivered to larger numbers of children. Future research should explore more effective delivery methods for SEL programs, particularly for older children and larger groups, such as integrating community components and information and communication technology into the programs.
AN  - WOS:001044901200001
AU  - Takizawa,
AU  - Y.
AU  - Bambling,
AU  - M.
AU  - Matsumoto,
AU  - Y.
AU  - Ishimoto,
AU  - Y.
AU  - Edirippulige,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3389/feduc.2023.1228269
L1  - internal-pdf://4225577216/Takisawa_2023.pdf
PY  - 2023
SP  - 20
T2  - Frontiers in Education
TI  - Effectiveness of universal school-based social-emotional learning programs in promoting social-emotional skills, attitudes towards self and others, positive social behaviors, and improving emotional and conduct problems among Japanese children: a meta-analytic review
UR  - &lt;Go to ISI&gt;://WOS:001044901200001
VL  - 8
ER  -
TY  - JOUR
AB  - Stay-play-talk (SPT) is a peer-mediated intervention that involves training peer implementers to stay in proximity to, play with, and talk to a focal child who has disabilities or lower social competence. This systematic review and meta-analysis investigated the contexts in which SPT interventions have been conducted, the methodological adequacy of the research assessing its effects, and the outcomes for both peer implementers and focal children. Studies have primarily occurred in inclusive preschool settings during free play activities, with researchers serving as facilitators. Average effects were positive and substantial for both peer implementers and focal children, although considerable heterogeneity across studies was observed. Additional research is needed to determine what peer implementer and focal child characteristics moderate intervention success, what modifications are needed for children who have complex communication needs, and optimal procedural variations (e.g., group size, training time). (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2023-30304-006
AU  - Ledford,
AU  - Jennifer
AU  - R.
AU  - Pustejovsky,
AU  - James
AU  - E.
DB  - November 2024.enl
DO  - /10.1177/1098300720983521
L1  - internal-pdf://3976956059/ledford-pustejovsky-2021-systematic-review-and.pdf
PY  - 2023
SP  - 65-77
T2  - Journal of Positive Behavior Interventions
TI  - Systematic review and meta-analysis of stay-play-talk interventions for improving social behaviors of young children
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.1177%2f1098300720983521
VL  - 25
ER  -
TY  - JOUR
AB  - This article provides a systematic review and meta-analysis of the current evidence for universal school-based (USB) social and emotional learning (SEL) interventions for students in kindergarten through 12th grade available from 2008 through 2020. 

The sample includes 424 studies from 53 countries, reflecting 252 discrete USB SEL interventions, involving 575,361 students. Results endorsed that, compared to control conditions, students who participate in USB SEL interventions experienced significantly improved skills, attitudes, behaviors, school climate and safety, peer relationships, school functioning, and academic achievement.

 Significant heterogeneity in USB SEL content, intervention features, context, and implementation quality moderated student experiences and outcomes. Strengths and limitations of this evidence and implications for future USB SEL research, policy, and practice are discussed.
AN  - 37448158
AU  - Cipriano,
AU  - C.
AU  - Strambler,
AU  - M.
AU  - J.
AU  - Naples,
AU  - L.
AU  - H.
AU  - Ha,
AU  - C.
AU  - Kirk,
AU  - M.
AU  - Wood,
AU  - M.
AU  - Sehgal,
AU  - K.
AU  - Zieher,
AU  - A.
AU  - K.
AU  - Eveleigh,
AU  - A.
AU  - McCarthy,
AU  - M.
AU  - Funaro,
AU  - M.
AU  - Ponnock,
AU  - A.
AU  - Chow,
AU  - J.
AU  - C.
AU  - Durlak,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/cdev.13968
L1  - internal-pdf://0886378652/Cipriano-2023-The state of evidence for social.pdf
PY  - 2023
SP  - 13
T2  - Child Development
TI  - The state of evidence for social and emotional learning: A contemporary meta-analysis of universal school-based SEL interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37448158
UR  - https://srcd.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cdev.13968?download=true
VL  - 13
ER  -
TY  - JOUR
AB  - Research has established associations between poor mental health and lifestyle risk behaviors among adolescents, yet gaps exist in understanding whether digital health interventions for adolescents targeting these behaviors will improve mental health and wellbeing. This study aimed to evaluate how effective digital health interventions targeting lifestyle risk behaviors are in improving mental health/wellbeing among adolescents (10-24 years old). We also aimed to understand how effects vary by participant and intervention characteristics, and intervention adherence and engagement. Through systematic review with meta-analysis, 5229 records were identified. 17 studies were included representing 9070 participants (15.3 mean age, 1.2 SD). Interventions had small but statistically non-significant positive effects on physical and psychosocial quality of life, depressive symptoms and anxiety at follow-up compared to usual care controls. Digital health delivery methods included text messaging, mobile applications, websites and email, or a combination of these. Intervention adherence, engagement and satisfaction were measured poorly across studies. Despite small changes, potential exists for digital health interventions to improve mental health or wellbeing outcomes among adolescents due to the shared nature of risk and protective factors for mental health and chronic diseases. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2024-00413-001
AU  - Raeside,
AU  - R.,
AU  - Jia,
AU  - S.S.,
AU  - Todd,
AU  - A.,
AU  - Hyun,
AU  - K.,
AU  - Singleton,
AU  - A.,
AU  - Gardner,
AU  - L.
AU  - A.,
AU  - Champion,
AU  - K.
AU  - E.,
AU  - Redfern,
AU  - J.,
AU  - Partridge,
AU  - S.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40894-023-00224-w
L1  - internal-pdf://3906905664/Raeside-2023-Are digital health interventions.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Adolescent Research Review
TI  - Are digital health interventions that target lifestyle risk behaviors effective for improving mental health and wellbeing in adolescents? A systematic review with meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2024-00413-001
UR  - https://link.springer.com/content/pdf/10.1007/s40894-023-00224-w.pdf
ER  -
TY  - JOUR
AB  - **Background:** 
Depression is a mental health disorder characterized by affective, somatic, and cognitive symptoms. Attention bias modification (ABM) has been widely used to treat depression. However, the results seem inconsistent. We conducted a systematic review and meta-analysis to investigate the efficacy of ABM for depression and to explore the optimal protocol of ABM. 

**Methods:** 
Seven databases were systematically searched from their inceptions to 5 October 2022 to include randomized controlled trials (RCTs) of ABM for depression. Two independent reviewers selected the eligible articles, extracted data, and evaluated the risk of bias using version 2 of the Cochrane risk-of-bias tool (ROB 2.0) for randomized trials. The primary outcome was the evaluation of depressive symptoms using widely accepted and validated scales. The secondary outcomes included rumination and attentional control. Meta-analysis was conducted by using RevMan (version 5.4) and Stata (version 12.0). Subgroup analyses and meta-regressions were performed to identify the source of heterogeneity. The certainty of the evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE). 

**Results:** 
A total of 19 trials involving 20 datasets (1,262 participants) were included. The overall risk of bias in one study was rated as low risk of bias, three studies were considered as high, and the remaining studies were some concerns. Compared with attention control training (ACT), ABM had a greater effect in the improvement of depression (SMD = -0.48, 95% CI -0.80 to -0.17, I&lt;sup&gt;2&lt;/sup&gt; = 82%) and rumination (MD = -3.46, 95% CI -6.06 to -0.87, I&lt;sup&gt;2&lt;/sup&gt; = 0%). No significant differences were observed in the attentional control outcome between ABM and ACT (MD = 3.07, 95% CI -0.52 to 6.65, I &lt;sup&gt;2&lt;/sup&gt; = 0%). Subgroup analysis demonstrated that adults exhibited a greater decrease in depression scores than adolescents. ABM using the dot-probe task, training target stimulus presented by face, and training directions by left-right were associated with better antidepressant effects. ABM training delivered in the laboratory tended to yield a better effect than those conducted at home. Sensitivity analysis indicated that the results were robust. The certainty of the evidence for all outcomes was low or very low, and publication bias may exist. 

**Conclusion:** 
Due to high heterogeneity and limited studies, not enough current evidence supported that ABM could be an effective intervention to relieve depressive symptoms. More rigorous RCTs are required to verify the benefits and to explore the optimal protocol of ABM training for depression. <b>Systematic Review Registration:</b> [PROSPERO], identifier [No. CRD42021279163].
AN  - 36970284
AU  - Xia,
AU  - H.
AU  - S.
AU  - Li,
AU  - Y.
AU  - X.
AU  - Zhang,
AU  - Q.
AU  - Y.
AU  - Zhong,
AU  - D.
AU  - L.
AU  - Liu,
AU  - X.
AU  - B.
AU  - Gou,
AU  - X.
AU  - Y.
AU  - Fan,
AU  - J.
AU  - Zhao,
AU  - J.
AU  - Zhang,
AU  - Y.
AU  - Ai,
AU  - S.
AU  - C.
AU  - Huang,
AU  - J.
AU  - X.
AU  - Li,
AU  - J.
AU  - Jin,
AU  - R.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2023.1098610
L1  - internal-pdf://1297802060/Xia.pdf
PY  - 2023
SP  - 1098610
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Attention bias modification for depression: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36970284
VL  - 14
ER  -
TY  - JOUR
AB  - Depression in childhood and adolescence is a public health problem due to its high prevalence and the impact it has in the individual develop-ment. There is clear evidence of the efficacy of Interpersonal Therapy (IPT) and Cognitive-Behavioural Therapy (CBT) in the treatment of depres-sion in children and adolescents; however, recent reviews and meta-analyses provide new perspectives for treatment. The purpose of this work is to synthesize the bibliography available through a systematic review of systematic reviews and meta-analysis that summarizes in a compre-hensive way the evidence of the last two decades on the effectiveness of psychological interventions for infant-juvenile depression. A systematic review of systematic reviews and meta-analyses was performed. A search was conducted in the Web of Science and Scopus databases. Eight records met the inclusion criteria, 2 were analysed in their entirety and from the remaining 6 the information needed for independent analysis was extracted. Seven different psychotherapies were studied: CBT and IPT were the most studied (n=7; 87.5%), followed by family therapy (n=5; 62.5%), psychodynamic therapy (n=3; 37.5%), behavioural therapy (n=3; 37.5%), computerised CBT (n=2; 25%), problem-solving therapy (n=1; 12.5%) and supportive therapy (n=1; 12.5%). IPT and CBT were shown to be effective in the treatment of adolescent depression. Half of the reviews (n=4; 50%) had a low methodological quality and the other half (n=4; 50%) were classified as critically low. In general, psychological interventions for child and adolescent depression produce significant, but modest effects. Specifically, IPT and CBT can be considered the main treatment alternatives for adolescent depression. There is insufficient data of specific psychological treatment for children diagnosed with a de-pressive disorder. It is suggested that research should be increased to improve the methodological quality and increase the number of studies aimed at the children population.
AN  - WOS:000975493000008
AU  - Espada,
AU  - J.
AU  - P.
AU  - Sanchez-Lopez,
AU  - A.
AU  - Morales,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.21134/rpcna.2023.10.1.6
L1  - internal-pdf://3201093736/Espada-2023-Effectiveness of psychological tre.pdf
PY  - 2023
SP  - 68-83
T2  - Revista De Psicologia Clinica Con Ninos Y Adolescentes
TI  - Effectiveness of psychological treatments for depression in childhood and adolescence: A review of reviews
UR  - &lt;Go to ISI&gt;://WOS:000975493000008
VL  - 10
ER  -
TY  - JOUR
AB  - **Background:**
Massage therapy for preterm newborns has received increasing attention in recent years due to its beneficial clinical outcomes. However, disagreements persist in different investigations. 

**Method:** 
We performed a systematic literature search in the Cochrane Library, Embase, PubMed, Web Science, and CINAHL to retrieve randomized controlled trials of premature infants receiving massage therapy and its impact on maternal and infant outcomes. Outcomes were mother-infant attachment, oxygen saturation, motor funtion, reflex, temperature, and calorie intake. The tool developed by the Cochrane collaboration assessed risk bias. With a 95% confidence interval (CI), the integration&#039;s results were presented as the mean difference or standardized mean difference. The registration number was CRD42022337849.

**Results:** 
Of 940 records retrieved, 15 trials were included. Massage therapy increased oxygen saturation (standardized mean difference (SMD) = 2.00, 95% CI [1.17 to 2.83], P &lt; 0.0001). Massage therapy can strengthen mother-infant attachment [SMD = 2.83, 95% CI (2.31 to 3.35), P &lt; 0.00001]. Other outcomes, including motor activity, relaxation, caloric intake, and temperature, did not differ significantly.

**Conclusion:**
Massage therapy can significantly improve oxygen saturation and strengthen maternal-infant attachment. However, prior to making a recommendation, additional research with a larger sample size and more rigorous design should be conducted due to the heterogeneity of studies in several outcomes.
AN  - 37719450
AU  - Zhang,
AU  - Y.
AU  - Duan,
AU  - C.
AU  - Cheng,
AU  - L.
AU  - Li,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fped.2023.1198730
L1  - internal-pdf://0590317343/Zhang-2023-Effects of massage therapy on prete.pdf
PY  - 2023
SP  - 1198730
T2  - Frontiers in Pediatrics
TI  - Effects of massage therapy on preterm infants and their mothers: a systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37719450
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10500070/pdf/fped-11-1198730.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Background**
Anorexia nervosa is a psychological condition characterised by self‐starvation and fear or wait gain or other body image disturbance. The first line of treatment is specific psychological therapy; however, there is no consensus on best practice for treating people who develop severe and enduring anorexia nervosa (SEAN). Notably, there is no universal definition of SEAN.

**Objectives**
To evaluate the benefits and harms of specific psychological therapies for severe and enduring anorexia nervosa compared with other specific therapies, non‐specific therapies, no treatment/waiting list, antidepressant medication, dietary counselling alone, or treatment as usual.

**Search methods**
We used standard, extensive Cochrane search methods. The last search date was 22 July 2022.

**Selection criteria**
We included parallel randomised controlled trials (RCTs) of people (any age) with anorexia nervosa of at least three years&#039; duration. Eligible experimental interventions were any specific psychological therapy for improved physical and psychological health in anorexia nervosa, conducted in any treatment setting with no restrictions in terms of number of sessions, modality, or duration of therapy. Eligible comparator interventions included any other specific psychological therapy for anorexia nervosa, non‐specific psychological therapy for mental health disorders, no treatment or waiting list, antipsychotic treatment (with or without psychological therapy), antidepressant treatment (with or without psychological therapy), dietary counselling, and treatment as usual as defined by the individual trials.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane. Our primary outcomes were clinical improvement (weight restoration to within the normal weight range for participant sample) and treatment non‐completion. Results were presented using the GRADE appraisal tool.

**Main results**
We found two eligible studies, but only one study provided usable data. This was a parallel‐group RCT of 63 adults with SEAN who had an illness duration of at least seven years. The trial compared outpatient cognitive behaviour therapy for SEAN (CBT‐SEAN) with specialist supportive clinical management for SEAN (SSCM‐SE) over eight months. It is unclear if there is any difference between the effect of CBT‐SEAN versus SSCM‐SE on clinical improvement at 12 months (risk ratio (RR) 1.42, 95% confidence interval (CI) 0.66 to 3.05) or treatment non‐completion (RR 1.72, 95% CI 0.45 to 6.59). There were no reported data on adverse effects. The trial was at high risk of performance and detection bias.

We rated the GRADE level of evidence as very low‐certainty for both primary outcomes, downgrading for imprecision and risk of bias concerns.

**Authors&#039; conclusions**
This review reports evidence from one trial that evaluated CBT‐SEAN versus SSCM‐SE. There was very low‐certainty evidence of little or no difference in clinical improvement and treatment non‐completion between the two therapies. There is a need for larger high‐quality trials to determine the benefits of specific psychological therapies for people with SEAN. These should take into account the duration of illness as well as participants&#039; previous experience with evidence‐based psychological therapy for anorexia nervosa.
AU  - Zhu,
AU  - j.
AU  - Hay,
AU  - P.
AU  - J.
AU  - Yang,
AU  - Y.
AU  - Le
AU  - Grange,
AU  - D.
AU  - Lacey,
AU  - J.
AU  - H.
AU  - Lujic,
AU  - S.
AU  - Smith,
AU  - C.
AU  - Touyz,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD011570.pub2
L1  - internal-pdf://1996720997/Zhu_et_al-2023-Cochrane_Database_of_Systematic.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Specific psychological therapies versus other therapies or notreatment for severe and enduring anorexia nervosa
ER  -
TY  - JOUR
AB  - BACKGROUND: Evidence about effective psychoeducational interventions to improve prenatal attachment, anxiety and depression has been increasing, but it lacks a complete synthesis of the results. The aim of this study is to evaluate the effect of psychoeducational intervention on prenatal attachment and anxiety/depression in pregnant women and their partners. 

METHODS: Ten databases were systematically searched to identify randomized controlled trials (RCTs) on the effectiveness of psychoeducational interventions on prenatal attachment from inception to March 2023, then manually screened to include studies of anxiety or depression. Two researchers assessed the methodological quality of the included studies using the Cochrane risk-of-bias tool and meta-analysis was performed using RevMan 5.4 software. 

RESULTS: Ten RCTs with a total of 700 pregnant women and 399 partners were included. Prenatal attachment scores after the intervention (standardized mean difference = 1.10, 95 % CI 0.65 to 1.55, P &lt;.00001) was significantly increased and anxiety scores (standardized mean difference = -0.99, 95 % CI -1.18 to -0.80, P &lt;.00001) was significantly lower. The subgroup analysis showed that the different prenatal attachment assessment tools were the source of heterogeneity in the combined results. The sensitivity analysis results showed reliable pooled results except for the studies using the self-made anxiety scale. 

CONCLUSION: This review suggests that psychoeducational interventions can effectively enhance prenatal attachment, reduce anxiety and depression, providing reference for the promotion of evidence-based practice of psychoeducational interventions in perinatal pregnant women and their partners.
AN  - 37689313
AU  - Wang,
AU  - X.
AU  - Xu,
AU  - H.
AU  - Liu,
AU  - X.
AU  - Yan,
AU  - J.
AU  - Chen,
AU  - C.
AU  - Li,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2023.08.131
L1  - internal-pdf://3719069613/Wang_2023_II.pdf
PY  - 2023
SP  - 33-44
T2  - Journal of Affective Disorders
TI  - Evaluating the effect of psychoeducational interventions on prenatal attachment and anxiety/depression in pregnant women and partners: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37689313
UR  - https://www.sciencedirect.com/science/article/pii/S0165032723011126?via%3Dihub
VL  - 342
ER  -
TY  - JOUR
AB  - Problem-solving (PS) has been identified as a therapeutic technique found in multiple evidence-based treatments for depression. To further understand for whom and how this intervention works, we undertook a systematic review of the evidence for PS&#039;s effectiveness in preventing and treating depression among adolescents and young adults. We searched electronic databases (PsycINFO, Medline, and Cochrane Library) for studies published between 2000 and 2022. Studies meeting the following criteria were included: (a) the intervention was described by authors as a PS intervention or including PS; (b) the intervention was used to treat or prevent depression; (c) mean or median age between 13-25 years; (d) at least one depression outcome was reported. Risk of bias of included studies was assessed using the Cochrane Risk of Bias 2.0 tool. A narrative synthesis was undertaken given the high level of heterogeneity in study variables. Twenty-five out of 874 studies met inclusion criteria. The interventions studied were heterogeneous in population, intervention, modality, comparison condition, study design, and outcome. Twelve studies focused purely on PS; 13 used PS as part of a more comprehensive intervention. Eleven studies found positive effects in reducing depressive symptoms and two in reducing suicidality. There was little evidence that the intervention impacted PS skills or that PS skills acted as a mediator or moderator of effects on depression. There is mixed evidence about the effectiveness of PS as a prevention and treatment of depression among AYA. Our findings indicate that pure PS interventions to treat clinical depression have the strongest evidence, while pure PS interventions used to prevent or treat sub-clinical depression and PS as part of a more comprehensive intervention show mixed results. Possible explanations for limited effectiveness are discussed, including missing outcome bias, variability in quality, dosage, and fidelity monitoring; small sample sizes and short follow-up periods.
AN  - 37643196
AU  - Metz,
AU  - K.
AU  - Lewis,
AU  - J.
AU  - Mitchell,
AU  - J.
AU  - Chakraborty,
AU  - S.
AU  - McLeod,
AU  - B.
AU  - D.
AU  - Bjorndal,
AU  - L.
AU  - Mildon,
AU  - R.
AU  - Shlonsky,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0285949
L1  - internal-pdf://3263734953/Metz-2023-Problem-solving interventions and de.pdf
PY  - 2023
SP  - e0285949
T2  - PLoS ONE [Electronic Resource]
TI  - Problem-solving interventions and depression among adolescents and young adults: A systematic review of the effectiveness of problem-solving interventions in preventing or treating depression
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=37643196
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0285949&amp;type=printable
VL  - 18
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) is a childhood-onset disorder characterized by pharmacological and non-pharmacological interventions. Despite the available treatment options and prevention measures, conventional treatments have several limitations. Digital therapeutics (DTx) like EndeavorRx is an emerging alternative to overcome these limitations. EndeavorRx is the first FDA-approved, game-based DTx approved for the treatment of pediatric ADHD. We investigated the effects of game-based DTx in randomised controlled trials (RCTs) on children and adolescents with ADHD. In this systematic review and meta-analysis, we searched PubMed, Embase, and PsycINFO databases up to January 2022. The protocol was registered (CRD42022299866). The assessor was defined as parents and teachers. The primary outcome was differences in inattention reported by the assessor, and the secondary outcome was differences in hyperactivity and hyperactivity/impulsivity reported by the assessor and the relative comparisons between game-based DTx, medicine, and control with indirect meta-analysis. Game-based DTx improved inattention more than the control upon assessment by assessors (standard mean difference (SMD) 0.28, 95% confidence interval (CI) 0.14-0.41; SMD 0.21, 95% CI 0.03-0.39, respectively), while medication improved inattention more than game-based DTx (SMD - 0.62, 95% CI - 1.04 to - 0.20) upon assessment by the teacher. Game-based DTx improved hyperactivity/impulsivity than the control upon assessment by assessors (SMD 0.28, 95% CI 0.03-0.53; SMD 0.30, 95% CI 0.05-0.55, respectively), and medication improved hyperactivity/impulsivity significantly than game-based DTx upon assessment by the teacher. Hyperactivity has not been reported extensively. As a result, game-based DTx had a more significant effect than the control, however medication was more effective. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-52957-001
AU  - Oh,
AU  - S.
AU  - Choi,
AU  - J.
AU  - Han,
AU  - D.
AU  - H.
AU  - Kim,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-023-02174-z
L1  - internal-pdf://2850997182/Oh_2023.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - European Child &amp; Adolescent Psychiatry
TI  - Effects of game-based digital therapeutics on attention deficit hyperactivity disorder in children and adolescents as assessed by parents or teachers: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-52957-001
UR  - https://link.springer.com/article/10.1007/s00787-023-02174-z
ER  -
TY  - JOUR
AB  - Mindfulness-based programs (MBPs) are increasingly used in educational institutions to enhance students&#039; mental health and resilience. However, reviews of the literature suggest this use may have outpaced the evidence base and further research is needed to better understand the mechanisms underlying these programs&#039; effectiveness and which outcomes are being affected. The purpose of this meta-analysis was to investigate the strength of MBPs&#039; effects on school adjustment and mindfulness outcomes while also considering the potential influence of study and program characteristics, including the role of comparison groups, students&#039; educational level, the type of program being used, and the facilitator&#039;s training and previous mindfulness experience. Following a systematic review of five databases, 46 studies using a randomized controlled design with students from preschool to undergraduate levels were selected. At post-program, the effect of MBPs compared to control groups was (a) small for overall school adjustment outcomes, academic performance, and impulsivity; (b) small to moderate for attention; and (c) moderate for mindfulness. No differences emerged for interpersonal skills, school functioning, or student behaviour. The effects of MBPs on overall school adjustment and mindfulness differed based on students&#039; educational level and the type of program being delivered. Moreover, only MBPs delivered by outside facilitators with previous experience of mindfulness had significant effects on either school adjustment or mindfulness. This meta-analysis provides promising evidence of the effectiveness of MBPs in educational contexts to improve students&#039; school adjustment outcomes beyond typically assessed psychological benefits, even when using randomized controlled designs.
AN  - 36914366
AU  - Mettler,
AU  - J.
AU  - Khoury,
AU  - B.
AU  - Zito,
AU  - S.
AU  - Sadowski,
AU  - I.
AU  - Heath,
AU  - N.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jsp.2022.10.007
L1  - internal-pdf://2015346849/Mettler.pdf
PY  - 2023
SP  - 43-62
T2  - Journal of School Psychology
TI  - Mindfulness-based programs and school adjustment: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36914366
VL  - 97
ER  -
TY  - JOUR
AB  - PROBLEM: Non-pharmacological distraction methods are novel alternatives that can help to alleviate pain and anxiety generated by venipuncture in the pediatric population. The aim is to determine the effectiveness of virtual reality, compared to cold and vibration devices (Buzzy R device), as a distraction method used during venipuncture in the management of pain and anxiety in children. 

ELIGIBILITY CRITERIA: Clinical trials, cohort and quasi-experimental studies, published between 2017 and 2022, in Spanish or English and pediatric age, found in Medline, the Cochrane Library, Scopus, Web Of Science, CINAHL and Embase databases. SAMPLE: Twenty-one studies were included and ten met the criteria for meta-analysis. 

RESULTS: Fifty-seven percent of the studies evaluate virtual reality, 33.3% the Buzzy R device and 9.5% both comparatively. The effectiveness of virtual reality in reducing pain (66.6%, n = 14) and anxiety (47.6%, n = 10) compared to standard care (control group), 95% CI = 1.53 [0.91-2.16], p &lt; 0.001, I2 = 78% and 95% CI = 1.53 [1.16-1.90]), p &lt; 0.001, I2 = 77% respectively is demonstrated. Similarly, the effectiveness of Buzzy R in reducing pain (42.9%, n = 9) and anxiety (23.8%, n = 5), 95% CI = 1.62 [0.90-2.34], p &lt; 0.001, I2 = 94% and 95% CI = 1.40 [0.06-2.20, p &lt; 0.001, I2 = 91% respectively is demonstrated. Comparatively, there is no significant difference between both methods 95% CI = 0.29 [-0.19-0.78], p = 0.24, I2 = 81%. 

CONCLUSIONS: The methods studied are effective in relieving pain and anxiety during venipuncture. Further research is needed on the level of satisfaction, adverse effects and cost-benefit. 

IMPLICATIONS: This study provides evidence of novel tools in daily practice to provide more humane, holistic and quality care.
AN  - 37603924
AU  - Merino-Lobato,
AU  - C.
AU  - Rodriguez-Gallego,
AU  - I.
AU  - Pabon-Carrasco,
AU  - M.
AU  - Romero-Castillo,
AU  - R.
AU  - Jimenez-Picon,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.pedn.2023.08.014
L1  - internal-pdf://2459541229/Merino_2023.pdf
PY  - 2023
SP  - 22-33
T2  - Journal of Pediatric Nursing
TI  - Virtual reality vs. buzzy R. efficacy in pain and anxiety management during pediatric venipuncture. Systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37603924
UR  - https://www.sciencedirect.com/science/article/pii/S0882596323002178?via%3Dihub
VL  - 73
ER  -
TY  - JOUR
AB  - OBJECTIVE: This meta-analysis examined the efficacy of available pharmacological and nonpharmacological interventions for irritability among youth with autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), disruptive behavior disorders (DBD), disruptive mood dysregulation disorder (DMDD), and/or severe mood dysregulation (SMD). 

METHOD: Literature searches were conducted in October 2020, resulting in 564 abstracts being reviewed to identify relevant papers, with 387 articles being reviewed in full. A random effects model was used for the meta-analysis, with subgroup meta-regressions run to assess effects of study design, intervention type, medication class, and clinical population. 

RESULTS: A total of 101 studies were included (80 pharmacological, 13 nonpharmacological, 8 combined). Despite high heterogeneity in effects (I&lt;sup&gt;2&lt;/sup&gt; = 94.3%), pooled posttreatment effect size for decreasing irritability was large (Hedges&#039; g = 1.62). Large effects were found for pharmacological (g = 1.85) and nonpharmacological (g = 1.11) interventions; moderate effects were found for combined interventions relative to monotherapy interventions (g = 0.69). Antipsychotic medications provided the largest effect for reducing irritability relative to all other medication classes and nonpharmacological interventions. A large effect was found for youth with ASD (g = 1.89), whereas a medium effect was found for youth with ADHD/DMDD/DBD/SMD (g = 0.64). 

CONCLUSION: This meta-analysis provides a comprehensive review of interventions targeting persistent nonepisodic irritability among youth with various psychiatric disorders. Strong evidence was found for medium-to-large effects across study design, intervention type, and clinical populations, with the largest effects for pharmacological interventions, particularly antipsychotic medications and combined pharmacological interventions, and interventions for youth with ASD.
AN  - 35714838
AU  - Breaux,
AU  - R.
AU  - Baweja,
AU  - R.
AU  - Eadeh,
AU  - H.
AU  - M.
AU  - Shroff,
AU  - D.
AU  - M.
AU  - Cash,
AU  - A.
AU  - R.
AU  - Swanson,
AU  - C.
AU  - S.
AU  - Knehans,
AU  - A.
AU  - Waxmonsky,
AU  - J.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2022.05.012
L1  - internal-pdf://1933350047/Breaux.pdf
PY  - 2023
SP  - 318-334
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Systematic Review and Meta-analysis: Pharmacological and Nonpharmacological Interventions for Persistent Nonepisodic Irritability
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35714838
VL  - 62
ER  -
TY  - JOUR
AB  - Autism spectrum disorder (ASD) has become a critical public health issue that affects more than 78 million people. In many recent studies, the authors have demonstrated that equine-assisted activities and therapies (EAATs) can substantially improve the social and behavioral skills of children with ASD. However, the qualities of the studies differ, and some authors reached opposite conclusions. In this review, we systematically and objectively examined the effectiveness of EAATs for people with ASD, combining both qualitative and quantitative methods. We searched five databases (PubMed, Scopus, ERIC, ProQuest, and MEDLINE) and added relevant references, and we identified 25 articles for data extraction and analysis. According to our results, EAAT programs can substantially improve the social and behavioral functioning and language abilities of children with ASD. However, among the subdomains, the results were inconsistent. According to the meta-analyses, there were considerable improvements in the social cognition, communication, irritability, and hyperactivity domains, but not in the domains of social awareness, mannerisms, motivation, lethargy, stereotypy, or inappropriate speech. Moreover, there was a lack of sufficient comparative data to conclude that EAAT programs lead to substantial improvements in motor and sensory functioning. In addition, among the included studies, we noted the indicator of whether EAAT programs decreased parental stress and improved family functioning, and although there were four articles in which the researchers considered this aspect, we were unable to draw any conclusions because of the insufficient data and conflicting descriptive evidence. However, we need to consider the improvement in parental mental health as a factor in the effectiveness of this complementary intervention. We hope that in future studies, researchers will focus on family functioning and conduct more randomized controlled trials (RCTs) with blinded assessments using different scales and measures.
AN  - 36767996
AU  - Xiao,
AU  - N.
AU  - Shinwari,
AU  - K.
AU  - Kiselev,
AU  - S.
AU  - Huang,
AU  - X.
AU  - Li,
AU  - B.
AU  - Qi,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/ijerph20032630
L1  - internal-pdf://1807553411/Xiao-2023-Effects of Equine-Assisted Activitie.pdf
PY  - 2023
SP  - 01
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Effects of Equine-Assisted Activities and Therapies for Individuals with Autism Spectrum Disorder: Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36767996
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-20-02630/article_deploy/ijerph-20-02630-v2.pdf?version=1675657608
VL  - 20
ER  -
TY  - JOUR
AB  - **Background:** 
Empirical evidence has shown that light therapy (LT) can reduce depression symptoms by stimulating circadian rhythms. However, there is skepticism and inconclusive results, along with confusion regarding dosing. The purpose of this study is to quantify light as a stimulus for the circadian system and create a dose-response relationship that can help reduce maladies among adolescents and young adults (AYAs). This will provide a reference for light exposure and neural response, which are crucial in the neuropsychological mechanism of light intervention. The study also aims to provide guidance for clinical application. 

**Methods:** 
The latest quantitative model of CL&lt;sub&gt;A&lt;/sub&gt; (circadian light) and CS&lt;sub&gt;t,f&lt;/sub&gt; (circadian stimulus) was adopted to quantify light dose for circadian phototransduction in youth depression-related light therapy. Articles published up to 2023 through Web of Science, Cochrane Library, Medline (OVID), CINAHL, APA PsycINFO, Embase, and Scholars were retrieved. A meta-analysis of 31 articles (1,031 subjects) was performed using Stata17.0, CMA3.0 (comprehensive meta-analysis version 3.0) software, and Python 3.9 platform for light therapy efficacy comparison and dose-response quantification. 

**Results:** 
Under various circadian stimulus conditions (0.1 &lt; CS&lt;sub&gt;t,f&lt;/sub&gt; &lt; 0.7) of light therapy (LT), malady reductions among AYAs were observed (pooled SMD = -1.59, 95%CI = -1.86 to -1.32; z = -11.654, p = 0.000; I&lt;sup&gt;2&lt;/sup&gt; = 92.8%), with temporal pattern (p = 0.044) and co-medication (p = 0.000) suggested as main heterogeneity sources. For the efficacy advantage of LT with a higher circadian stimulus that is assumed to be influenced by visualization, co-medication, disease severity, and time pattern, sets of meta-analysis among random-controlled trials (RCTs) found evidence for significant efficacy of circadian-active bright light therapy (BLT) over circadian-inactive dim red light (SMD = -0.65, 95% CI = -0.96 to -0.34; z = -4.101, p = 0.000; I&lt;sup&gt;2&lt;/sup&gt; = 84.9%) or circadian-active dimmer white light (SMD = -0.37, 95% CI = -0.68 to -0.06; z = -2.318, p = 0.02; I&lt;sup&gt;2&lt;/sup&gt; = 33.8%), whereas green-blue, circadian-active BLT showed no significant superiority over circadian-inactive red/amber light controls (SMD = -0.21, 95% CI = -0.45 to 0.04; z = -2.318, p = 0.099; I&lt;sup&gt;2&lt;/sup&gt; = 0%). Overall, circadian-active BLT showed a greater likelihood of clinical response than dim light controls, with increased superiority observed with co-medication. For pre-to-post-treatment amelioration and corresponding dose-response relationship, cumulative duration was found more influential than other categorical (co-medication, severity, study design) or continuous (CS&lt;sub&gt;t,f&lt;/sub&gt;) variables. Dose-response fitting indicated that the therapeutic effect would reach saturation among co-medicated patients at 32-42 days (900-1,000 min) and 58-59 days (1,100-1,500 min) among non-medicated AYAs. When exerting high circadian stimulus of light therapy (0.6 &lt; CS&lt;sub&gt;t,f&lt;/sub&gt; &lt; 0.7), there was a significantly greater effect size in 1,000-1,500 min of accumulative duration than &lt;1,000 or &gt;1,500 min of duration, indicating a threshold for practical guidance. 

**Limitations:** 
The results have been based on limited samples and influenced by a small sample effect. The placebo effect could not be ignored. 

**Conclusions:** 
Although the superiority of LT with higher circadian stimulus over dimmer light controls remains unproven, greater response potentials of circadian-active BLT have been noticed among AYAs, taking co-medication, disease severity, time pattern, and visual characteristics into consideration. The dose-response relationship with quantified circadian stimulus and temporal pattern had been elaborated under various conditions to support clinical depression treatment and LT device application in the post-pandemic era.
AN  - 38259764
AU  - Chen,
AU  - R.
AU  - Yan,
AU  - Y.
AU  - Cheng,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpubh.2023.1257093
L1  - internal-pdf://2047046682/Chen-2023-Circadian light therapy and light do.pdf
PY  - 2023
SP  - 1257093
T2  - Frontiers in Public Health
TI  - Circadian light therapy and light dose for depressed young people: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38259764
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10800803/pdf/fpubh-11-1257093.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - Physical education stimulates brain plasticity. However, the effect of physical education interventions on socialization and communication skills in children and preadolescents with autism spectrum disorder is unknown.

 To review and qualitatively describe studies published between 2012 and 2022 that intervened with physical education to generate changes in socialization and communication skills in children and preadolescents with autism spectrum disorder. 

The search was designed following the PRISMA (R) guidelines for systematic reviews and meta-analyses and performed in Web of Science, Scopus, and PubMed between 2012 and 2022. 

Fourteen studies were included in the systematic review and nine in the meta-analysis. 

Physical education was shown to be effective in increasing socialization and communication skills in children and preadolescents with autism spectrum disorder.
AN  - WOS:001091253900001
AU  - Ojeda,
AU  - A.
AU  - H.
AU  - Barahona-Fuentes,
AU  - G.
AU  - Ordenes,
AU  - F.
AU  - V.
AU  - Tapia,
AU  - M.
AU  - M.
AU  - Yeomans-Cabrera,
AU  - M.
AU  - M.
AU  - Martinez-Libano,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1007/s40489-023-00410-5
L1  - internal-pdf://3049529048/Ojeda-2023-Effects of Physical Education on So.pdf
PY  - 2023
SP  - 16
T2  - Review Journal of Autism and Developmental Disorders
TI  - Effects of Physical Education on Socializing and Communicating Among Children and Preadolescents with Autism Spectrum Disorder: a Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001091253900001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-023-00410-5.pdf
ER  -
TY  - JOUR
AB  - Antidepressant medication (ADM)-only, psychotherapy-only, and their combination are the first-line treatment options for major depressive disorder (MDD). Previous meta-analyses of randomized controlled trials (RCTs) established that psychotherapy and combined treatment were superior to ADM-only for MDD treatment remission or response. 

The current meta-analysis extended previous ones by determining the comparative efficacy of ADM-only, psychotherapy-only, and combined treatment on suicide attempts and other serious psychiatric adverse events (i.e. psychiatric emergency department [ED] visit, psychiatric hospitalization, and/or suicide death; SAEs). Peto odds ratios (ORs) and their 95% confidence intervals were computed from the present random-effects meta-analysis. 

Thirty-four relevant RCTs were included. Psychotherapy-only was stronger than combined treatment (1.9% v. 3.7%; OR 1.96 [1.20-3.20], p = 0.012) and ADM-only (3.0% v. 5.6%; OR 0.45 [0.30-0.67], p = 0.001) in decreasing the likelihood of SAEs in the primary and trim-and-fill sensitivity analyses. Combined treatment was better than ADM-only in reducing the probability of SAEs (6.0% v. 8.7%; OR 0.74 [0.56-0.96], p = 0.029), but this comparative efficacy finding was non-significant in the sensitivity analyses. Subgroup analyses revealed the advantage of psychotherapy-only over combined treatment and ADM-only for reducing SAE risk among children and adolescents and the benefit of combined treatment over ADM-only among adults. 

Overall, psychotherapy and combined treatment outperformed ADM-only in reducing the likelihood of SAEs, perhaps by conferring strategies to enhance reasons for living. Plausibly, psychotherapy should be prioritized for high-risk youths and combined treatment for high-risk adults with MDD.
AN  - 37964436
AU  - Zainal,
AU  - N.
AU  - H.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1017/S0033291723003306
L1  - internal-pdf://0886645612/Zainal-2023-Is combined antidepressant medicat.pdf
PY  - 2023
SP  - 1-16
T2  - Psychological Medicine
TI  - Is combined antidepressant medication (ADM) and psychotherapy better than either monotherapy at preventing suicide attempts and other psychiatric serious adverse events for depressed patients? A rare events meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37964436
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/C85C9A9E3FB14EEAE69728F6C0B498C5/S0033291723003306a.pdf/div-class-title-is-combined-antidepressant-medication-adm-and-psychotherapy-better-than-either-monotherapy-at-preventing-suicide-attempts-and-other-psychiatric-serious-adverse-events-for-depressed-patients-a-rare-events-meta-analysis-div.pdf
ER  -
TY  - JOUR
AB  - Sexual and dating violence (SDV) by male youth (&lt;= 25 years)-including sexual harassment, emotional partner violence, and rape-is a worldwide problem. The goal of this preregistered (PROSPERO, ID: CRD42022281220) systematic review was to map existing SDV prevention programs aimed at male youth, including their characteristics (e.g., content, intensity), intended psychosexual outcomes, and empirically demonstrated effectiveness, guided by the principles of the theory of planned behavior (TPB). We conducted searches in six online databases for published, peer-reviewed quantitative effectiveness studies on multi-session, group focused, and interaction based SDV prevention programs for male youth ending March 2022. After screening of 21,156 hits using PRISMA guidelines, 15 studies on 13 different programs, from four continents were included. Narrative analysis showed, first, broad ranges in program intensity (2-48 h total), and few program curricula included explicit discussion of relevant aspects of the TPB. Second, programs&#039; main intended psychosexual outcomes were to change SDV experiences, or related attitudes, or norms. Third, significant effects were found mostly on longer term behaviors and short-term attitudes. Other theoretical proxies of SDV experiences, such as social norms and perceived behavioral control, were sparsely investigated; thus, program effectiveness on these outcomes remains largely unknown. Assessed with the Cochrane Risk of Bias Tool, moderate to serious risk of bias arose in all studies. We present concrete suggestions for program content, such as explicit attention to victimization and masculinity and discuss best practices for evaluation research, including assessments of program integrity, and examining relevant theoretical proxies of SDV. Copyright &copy; 2023. The Author(s).
AU  - Verbeek,
AU  - M.
AU  - Weeland,
AU  - J.
AU  - Luijk,
AU  - M.
AU  - van
AU  - de
AU  - Bongardt,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10508-023-02596-5
L1  - internal-pdf://1589933622/Verbeek-2023-Sexual and Dating Violence Preven.pdf
PY  - 2023
T2  - Archives of sexual behavior
TI  - Sexual and Dating Violence Prevention Programs for Male Youth: A Systematic Review of Program Characteristics, Intended Psychosexual Outcomes, and Effectiveness
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37226034
UR  - https://link.springer.com/content/pdf/10.1007/s10508-023-02596-5.pdf
ER  -
TY  - JOUR
AB  - Tablet-mediated interventions have shown promise in improving the mathematical skills of individuals with autism spectrum disorder (ASD) and/or intellectual disability (ID). This meta-analysis aims to provide a quantitative synthesis of single-case experimental studies of using tablet-mediated interventions to teach mathematics to individuals with ASD and/or ID. Twenty-seven published studies between 2012 and 2022 were included. The Tau-U effect size index was used to gauge the overall effect size of tablet-mediated interventions. The obtained effect size (Tau-U = 0.98, 95% CI 0.92-1.00) indicated large improvements in mathematics performance after using tablet-mediated interventions. The analysis of potential moderating variables, including participant characteristics, intervention components, and target mathematical skills found no statistically significant moderators. Implications for researchers and practitioners who use tablet-mediated interventions to teach mathematics to individuals with ASD and/or ID are also discussed.
AN  - WOS:001041296300001
AU  - Liu,
AU  - D.
AU  - Mao,
AU  - Y.
AU  - W.
AU  - Cai,
AU  - W.
AU  - W.
AU  - Lei,
AU  - Q.
AU  - L.
AU  - Kang,
AU  - R.
AU  - Zeng,
AU  - Y.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/01626434231180579
L1  - internal-pdf://3713600375/Liu_2023_III.pdf
PY  - 2023
SP  - 17
T2  - Journal of Special Education Technology
TI  - Meta-Analysis of Tablet-Mediated Interventions to Teach Mathematics for Individuals With Autism Spectrum Disorder and/or Intellectual Disability
UR  - &lt;Go to ISI&gt;://WOS:001041296300001
UR  - https://journals.sagepub.com/doi/10.1177/01626434231180579
ER  -
TY  - JOUR
AB  - **Objectives**
Reducing and eliminating the use of Restrictive Practices (RPs) is consistent with the United Nations Convention on the Rights of Persons with Disabilities (UNCRPD). This systematic review examines the effectiveness of organisation-wide interventions in reducing behaviours of concern (BoC) and the use of RPs in people with a neurodevelopmental disorder (NDD). 

**Methods**
19 electronic databases were searched up to February 2021 for literature, with no language restrictions applied. This systematic review of interventions included any publication aimed at reducing the use of RPs and/or BoC in organisations providing services to people with any NDD. 

**Results**
A total of 15 studies were included in the review. Seven were randomised controlled trials (RCTs) and eight non-RCTs. Most studies focussed on workplace education and training. There was evidence that staff training in Positive Behaviour Support (PBS) and mindfulness-based PBS (MBPBS) reduced aggression, the use of chemical and physical restraints, and peer and staff injuries (MBPBS) in the medium term. A multi-component intervention also showed evidence of a reduction in behaviours of concern in the medium and long term. 

**Conclusions**
A number of studies showed that organisation-wide PBS training, particularly MBPBS training, can reduce BoC and the use of RPs. One multi-component study also substantially reduced BoC. Organisational strategies such as these can improve the rights of people with disability by reducing the use of RPs. However, the generalisability of these findings may be limited as all comparisons were single studies which had potential biases. We are also not able to say whether these findings can be generalised to children, and adults with other neurodevelopmental disabilities, as all but one study focused on adults with intellectual disabilities. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2024-30295-001
AU  - Iffland,
AU  - M.
AU  - A.
AU  - Gillies,
AU  - D.
AU  - M.
AU  - Aghaji,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s41252-023-00370-1
L1  - internal-pdf://2575350113/Iffland-2023-Organisation-wide interventions t.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Advances in Neurodevelopmental Disorders
TI  - Organisation-wide interventions to reduce behaviours of concern as well as restrictive practices with children or adults with a neurodevelopmental disorder: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2024-30295-001
UR  - https://link.springer.com/article/10.1007/s41252-023-00370-1
UR  - https://link.springer.com/content/pdf/10.1007/s41252-023-00370-1.pdf
ER  -
TY  - JOUR
AB  - The World Health Organisation defines health in terms of wellbeing, and wellbeing has become both a construct and a measure of impact in early intervention and prevention programs in schools. In Australia, schools report on their wellbeing initiatives and there is a plethora of government-funded wellbeing programs already in place in schools. However, education systems and stakeholders worldwide are facing significant challenges with mixed evaluation results of program impact and intervention effect. To better support students, schools, school-based healthcare workers, and community, it is important to know about the effectiveness of school-based programs; yet in the last decade, there has been no national appraisal of these programs in Australia. This systematic review aims to report on the effectiveness of Australian school-based wellbeing programs through a search of 13 databases. Out of 2888 articles, 29 met inclusion criteria. The results found that seventeen interventions comprising 80% of the total number of participants reported no statistically significant intervention effect on wellbeing outcomes. We argue that supporting wellbeing through robust program intervention is important as wellbeing presents both an indication of later onset of more serious mental health issues, and an opportunity for early intervention to break the trajectory leading to full disorder.
AN  - 37569048
AU  - Gunawardena,
AU  - H.
AU  - Voukelatos,
AU  - A.
AU  - Nair,
AU  - S.
AU  - Cross,
AU  - S.
AU  - Hickie,
AU  - I.
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph20156508
L1  - internal-pdf://2544253136/Gunawardena-2023-Efficacy and Effectiveness of.pdf
PY  - 2023
SP  - 02
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Efficacy and Effectiveness of Universal School-Based Wellbeing Interventions in Australia: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37569048
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-14-00156/article_deploy/ijerph-14-00156.pdf?version=1486465342
VL  - 20
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis aimed to investigate the efficacy and acceptability of systemic therapy in treatment of children and adolescents with depression. Six databases were used to identify randomized controlled trials (RCTs) applying systemic therapy (ST). Random-effects meta-analyses were conducted to estimate efficacy and acceptability of intervention. The primary outcome of efficacy was defined as changes of depressive symptoms. Secondary outcomes of efficacy included response rate and function improvement. Nine RCTs (n = 640) were included. For the immediate efficacy of depressive symptoms, ST was superior to waiting-list (WL) (n = 117, SMD -1.75, 95% CI -2.96 to -0.54), similar to treat as usual (TAU) (n = 146, SMD -0.45, 95% CI -1.14 to 0.24) or supportive psychotherapy (n = 263, SMD -0.04, 95%CI -0.28 to 0.20), superior to psychodynamic psychotherapy (n = 72, SMD -0.66, 95%CI -1.13 to -0.18) and inferior to cognitive behavior therapy (CBT) (n = 72, SMD 0.58, 95%CI 0.11 to 1.05). About response rate, ST (47.7%) was superior to WL, similar to TAU and supportive therapy and dynamic psychotherapy, and inferior to CBT. ST was comparable to CBT, supportive therapy and dynamic therapy on function improvement (SMD 0.18, 95% CI -0.12 to 0.49). As for acceptability, no significant difference was found between ST (11.9%) and controls (OR 0.97, 95%CI 0.61 to 1.56). In treating youths with depression, ST was superior to WL, similar to supportive psychotherapy and TAU, inferior to CBT, similar or superior to dynamic psychotherapy on symptoms relief. ST demonstrated comparable acceptability to TAU and guideline-recommended psychotherapies. Considering small sample size, the conclusion should be treated cautiously. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-61385-001
AU  - Huang,
AU  - Y.
AU  - Li,
AU  - Y.
AU  - Haun,
AU  - M.
AU  - W.
AU  - Xie,
AU  - R.
AU  - Yang,
AU  - L.
AU  - Retzlaff,
AU  - R.
AU  - Qian,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12144-023-04558-5
L1  - internal-pdf://3871939651/Huang-2023-Systemic therapy for children and a.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Current Psychology: A Journal for Diverse Perspectives on Diverse Psychological Issues
TI  - Systemic therapy for children and adolescents with depression: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-61385-001
UR  - https://link.springer.com/article/10.1007/s12144-023-04558-5
UR  - https://link.springer.com/content/pdf/10.1007/s12144-023-04558-5.pdf
ER  -
TY  - JOUR
AB  - Infant sleep problems are prevalent and have a negative impact on infant growth and development, maternal sleep, and maternal mood. The effects of psychosocial sleep interventions on infant sleep and maternal sleep and mood are unclear. This study aimed to systematically evaluate the effects of psychosocial sleep interventions on improving infant sleep, including nocturnal total sleep time, daytime total sleep, total sleep time, night wakings, and maternal sleep and mood problems (ie, depression and fatigue). We searched PubMed, Web of Science, Cochrane Library, Embase, EBSCO, OpenGrey, DeepBlue, China National Knowledge Infrastructure, and Wanfang databases. We focused on randomized controlled trials examining the effectiveness of psychosocial sleep interventions on infant sleep. The study was preregistered at the International Prospective Register of Systematic Reviews (CRD42022301654). Thirteen studies from 5889 articles were included in the review, which found that psychosocial sleep interventions improved infant nocturnal total sleep time (0.28 [0.04-0.52], p &lt; 0.05, I&lt;sup&gt;2&lt;/sup&gt; = 83.9%) and maternal depression (-0.10 [-0.28 to -0.08], p &lt; 0.05, I&lt;sup&gt;2&lt;/sup&gt; = 8.7%). To test and explore heterogeneity, we used the I&lt;sup&gt;2&lt;/sup&gt; statistic, influence analysis, subgroup analyses, and subgroup meta-analyses. Funnel plots and Egger&#039;s tests revealed no evidence of publication bias. Psychosocial sleep interventions improved infant nocturnal total sleep time and maternal depression. Future research should include more randomized controlled trials examining the effect of psychosocial sleep interventions on the improvement of maternal sleep and fatigue.
AN  - 37532607
AU  - Liu,
AU  - J.
AU  - Sun,
AU  - Y.
AU  - Fan,
AU  - X.
AU  - Zang,
AU  - T.
AU  - Han,
AU  - L.
AU  - Slack,
AU  - J.
AU  - E.
AU  - Bai,
AU  - J.
AU  - Chen,
AU  - H.
AU  - Liu,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.sleh.2023.06.010
L1  - internal-pdf://0338598473/Liu_2023_II.pdf
PY  - 2023
SP  - 31
T2  - Sleep Health
TI  - Effects of psychosocial sleep interventions on improving infant sleep and maternal sleep and mood: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37532607
UR  - https://www.sciencedirect.com/science/article/pii/S2352721823001328?via%3Dihub
VL  - 31
ER  -
TY  - JOUR
AB  - **Background and objective:** 
The potential impact of gut health on general physical and mental well-being, particularly in relation to brain function, has led to a growing interest in the potential health advantages of prebiotics, probiotics, and synbiotics for the management of ASD. A comprehensive meta-analysis and systematic review was conducted in order to evaluate the effectiveness and protection of many drugs targeted at manipulating the microbiota in the treatment of ASD.

**Methods:** 
The present study employed a comprehensive examination of various electronic databases yielded a total of 3,393 records that were deemed possibly pertinent to the study. RCTs encompassed a total of 720 individuals between the ages of 2 and 17, as well as 112 adults and participants ranging from 5 to 55 years old, all of whom had received a diagnosis of ASD.

**Results:** 
Overall, 10 studies reported Autism-Related Behavioral Symptoms (ARBS). Regarding the enhancement of autism-related behavioral symptoms, there wasn&#039;t a statistically significant difference between the intervention groups (combined standardized mean difference = -0.07, 95% confidence interval: -0.39 to 0.24, Z = 0.46, p = 0.65). We observed that in the patients with ASD treated with probiotic frontopolar&#039;s power decreased significantly from baseline to endpoints in beta band (Baseline: 13.09 +/- 3.46, vs. endpoint: 10.75 +/- 2.42, p = 0.043, respectively) and gamma band (Baseline: 5.80 +/- 2.42, vs. endpoint: 4.63 +/- 1.39, p = 0.033, respectively). Among all tested biochemical measures, a significant negative correlation was found between frontopolar coherence in the gamma band and TNF-alpha (r = -0.30, p = 0.04).

**Conclusion:** 
The existing body of research provides a comprehensive analysis of the developing evidence that indicates the potential of probiotics, prebiotics, and synbiotics as therapeutic therapies for ASD. Our findings revealed that those there was no significant effect of such therapy on autism-related behavioral symptoms, it has significant effect on the brain connectivity through frontopolar power in beta and gamma bands mediated by chemicals and cytokines, such as TNF-alpha. The psychobiotics showed no serious side-effects.
AN  - WOS:001129948600001
AU  - Rahim,
AU  - F.
AU  - Toguzbaeva,
AU  - K.
AU  - Qasim,
AU  - N.
AU  - H.
AU  - Dzhusupov,
AU  - K.
AU  - O.
AU  - Zhumagaliuly,
AU  - A.
AU  - Khozhamkul,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3389/fnut.2023.1294089
L1  - internal-pdf://0423659051/fnut-10-1294089.cleaned.pdf
PY  - 2023
SP  - 13
T2  - Frontiers in Nutrition
TI  - Probiotics, prebiotics, and synbiotics for patients with autism spectrum disorder: a meta-analysis and umbrella review
UR  - &lt;Go to ISI&gt;://WOS:001129948600001
VL  - 10
ER  -
TY  - JOUR
AB  - This meta-analysis investigated the effects of computerized cognitive training (CCT) on clinical, neuropsychological and academic outcomes in individuals with attention-deficit/hyperactivity disorder (ADHD). The authors searched PubMed, Ovid, and Web of Science until 19th January 2022 for parallel-arm randomized controlled trials (RCTs) using CCT in individuals with ADHD. Random-effects meta-analyses pooled standardized mean differences (SMD) between CCT and comparator arms. RCT quality was assessed with the Cochrane Risk of Bias 2.0 tool (PROSPERO: CRD42021229279). Thirty-six RCTs were meta-analysed, 17 of which evaluated working memory training (WMT). Analysis of outcomes measured immediately post-treatment and judged to be &quot;probably blinded&quot; (PBLIND; trial n = 14) showed no effect on ADHD total (SMD = 0.12, 95%CI[-0.01 to -0.25]) or hyperactivity/impulsivity symptoms (SMD = 0.12, 95%[-0.03 to-0.28]). These findings remained when analyses were restricted to trials (n: 5-13) with children/adolescents, low medication exposure, semi-active controls, or WMT or multiple process training. There was a small improvement in inattention symptoms (SMD = 0.17, 95%CI[0.02-0.31]), which remained when trials were restricted to semi-active controls (SMD = 0.20, 95%CI[0.04-0.37]), and doubled in size when assessed in the intervention delivery setting (n = 5, SMD = 0.40, 95%CI[0.09-0.71]), suggesting a setting-specific effect. CCT improved WM (verbal: n = 15, SMD = 0.38, 95%CI[0.24-0.53]; visual-spatial: n = 9, SMD = 0.49, 95%CI[0.31-0.67]), but not other neuropsychological (e.g., attention, inhibition) or academic outcomes (e.g., reading, arithmetic; analysed n: 5-15). Longer-term improvement (at ~6-months) in verbal WM, reading comprehension, and ratings of executive functions were observed but relevant trials were limited in number (n: 5-7). There was no evidence that multi-process training was superior to working memory training. In sum, CCT led to shorter-term improvements in WM, with some evidence that verbal WM effects persisted in the longer-term. Clinical effects were limited to small, setting specific, short-term effects on inattention symptoms.
AN  - 36977764
AU  - Westwood,
AU  - S.
AU  - J.
AU  - Parlatini,
AU  - V.
AU  - Rubia,
AU  - K.
AU  - Cortese,
AU  - S.
AU  - Sonuga-Barke,
AU  - E.
AU  - J.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1038/s41380-023-02000-7
L1  - internal-pdf://3305756330/Westwood-2023-Computerized cognitive training.pdf
PY  - 2023
SP  - 29
T2  - Molecular Psychiatry
TI  - Computerized cognitive training in attention-deficit/hyperactivity disorder (ADHD): a meta-analysis of randomized controlled trials with blinded and objective outcomes
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36977764
UR  - https://www.nature.com/articles/s41380-023-02000-7.pdf
VL  - 29
ER  -
TY  - JOUR
AB  - **Background**: The current systematic review and meta-analysis aimed to explore the evidence base to date for exercise interventions/interventions that aim to increase physical activity using a modality that can be accessed from home (i.e., online or video-based programs), and its effects on anxiety and depression in children and adolescents. 

**Methods**: A broad search was conducted using six databases (PubMed, Web of Science, CINAHL, PsychINFO, ERIC and Scopus) on February 23, 2022. Studies with children or adolescents between the ages 5 and 18 years were included. Of the 2527 records that were identified, nine studies met the full-inclusion criteria. Their quality was assessed by two independent researchers using the Cochrane risk-of-bias tool for randomized trials (RoB 2) and Quality Assessment Tool for Before-After (Pre-Post) Studies with No Control Group. Meta analyses were conducted for studies that specifically assessed anxiety and depression. 

**Results**: The overall results indicated that there is some evidence suggesting the positive effects of exercise interventions delivered online in reducing children&#039;s and adolescents&#039; anxiety (d = -0.99, 95% confidence interval [CI]: -1.12 to -0.86). Meanwhile, there seems to be insufficient evidence for its efficacy in reducing low mood (d = -0.42; 95% CI: -0.84 to 0.01). Motivational and coaching based interventions to increase levels of physical activity may be limited in their efficacy, whilst having children exercise along with a video or live sessions online appears promising. 

**Conclusion**: The current preliminary review revealed potential benefits of at-home interventions that had children and adolescents exercise along with a video in improving anxiety.
AN  - 38868129
AU  - Yamaguchi,
AU  - R.
AU  - Kawahara,
AU  - T.
AU  - Kotani,
AU  - T.
AU  - Yazawa,
AU  - R.
AU  - Suzuki,
AU  - A.
AU  - Kano,
AU  - Y.
AU  - Ishii-Takahashi,
AU  - A.
DB  - Juni 24.enl
DO  - /10.1002/pcn5.103
L1  - internal-pdf://1165061870/Yamaguchi-2023-The effectiveness of exercise p.pdf
PY  - 2023
SP  - e103
T2  - Pcn Report
TI  - The effectiveness of exercise programs accessible from home on children&#039;s and adolescents&#039; emotional well-being: Systematic review &amp; meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;DO=10.1002%2fpcn5.103
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pcn5.103?download=true
VL  - 2
ER  -
TY  - JOUR
AB  - **Background**
Acceptable, effective and feasible support strategies (interventions) for parents experiencing complex post‐traumatic stress disorder (CPTSD) symptoms or with a history of childhood maltreatment may offer an opportunity to support parental recovery, reduce the risk of intergenerational transmission of trauma and improve life‐course trajectories for children and future generations. However, evidence relating to the effect of interventions has not been synthesised to provide a comprehensive review of available support strategies. This evidence synthesis is critical to inform further research, practice and policy approaches in this emerging area.

**Objectives**
To assess the effects of interventions provided to support parents who were experiencing CPTSD symptoms or who had experienced childhood maltreatment (or both), on parenting capacity and parental psychological or socio‐emotional wellbeing.

**Search methods**
In October 2021 we searched CENTRAL, MEDLINE, Embase, six other databases and two trials registers, together with checking references and contacting experts to identify additional studies.

**Selection criteria**
All variants of randomised controlled trials (RCTs) comparing any intervention delivered in the perinatal period designed to support parents experiencing CPTSD symptoms or with a history of childhood maltreatment (or both), to any active or inactive control. Primary outcomes were parental psychological or socio‐emotional wellbeing and parenting capacity between pregnancy and up to two years postpartum.

**Data collection and analysis**
Two review authors independently assessed the eligibility of trials for inclusion, extracted data using a pre‐designed data extraction form, and assessed risk of bias and certainty of evidence. We contacted study authors for additional information as required. We analysed continuous data using mean difference (MD) for outcomes using a single measure, and standardised mean difference (SMD) for outcomes using multiple measures, and risk ratios (RR) for dichotomous data. All data are presented with 95% confidence intervals (CIs). We undertook meta‐analyses using random‐effects models.

**Main results**
We included evidence from 1925 participants in 15 RCTs that investigated the effect of 17 interventions. All included studies were published after 2005. Interventions included seven parenting interventions, eight psychological interventions and two service system approaches. The studies were funded by major research councils, government departments and philanthropic/charitable organisations. All evidence was of low or very low certainty.

Parenting interventions

Evidence was very uncertain from a study (33 participants) assessing the effects of a parenting intervention compared to attention control on trauma‐related symptoms, and psychological wellbeing symptoms (postpartum depression), in mothers who had experienced childhood maltreatment and were experiencing current parenting risk factors. Evidence suggested that parenting interventions may improve parent‐child relationships slightly compared to usual service provision (SMD 0.45, 95% CI ‐0.06 to 0.96; I2 = 60%; 2 studies, 153 participants; low‐certainty evidence). There may be little or no difference between parenting interventions and usual perinatal service in parenting skills including nurturance, supportive presence and reciprocity (SMD 0.25, 95% CI ‐0.07 to 0.58; I2 = 0%; 4 studies, 149 participants; low‐certainty evidence). No studies assessed the effects of parenting interventions on parents&#039; substance use, relationship quality or self‐harm.

Psychological interventions

Psychological interventions may result in little or no difference in trauma‐related symptoms compared to usual care (SMD ‐0.05, 95% CI ‐0.40 to 0.31; I2 = 39%; 4 studies, 247 participants; low‐certainty evidence). Psychological interventions may make little or no difference compared to usual care to depression symptom severity (8 studies, 507 participants, low‐certainty evidence, SMD ‐0.34, 95% CI ‐0.66 to ‐0.03; I2 = 63%). An interpersonally focused cognitive behavioural analysis system of psychotherapy may slightly increase the number of pregnant women who quit smoking compared to usual smoking cessation therapy and prenatal care (189 participants, low‐certainty evidence). A psychological intervention may slightly improve parents&#039; relationship quality compared to usual care (1 study, 67 participants, low‐certainty evidence). Benefits for parent‐child relationships were very uncertain (26 participants, very low‐certainty evidence), while there may be a slight improvement in parenting skills compared to usual care (66 participants, low‐certainty evidence). No studies assessed the effects of psychological interventions on parents&#039; self‐harm.

Service system approaches

One service system approach assessed the effect of a financial empowerment education programme, with and without trauma‐informed peer support, compared to usual care for parents with low incomes. The interventions increased depression slightly (52 participants, low‐certainty evidence). No studies assessed the effects of service system interventions on parents&#039; trauma‐related symptoms, substance use, relationship quality, self‐harm, parent‐child relationships or parenting skills.

**Authors&#039; conclusions**
There is currently a lack of high‐quality evidence regarding the effectiveness of interventions to improve parenting capacity or parental psychological or socio‐emotional wellbeing in parents experiencing CPTSD symptoms or who have experienced childhood maltreatment (or both). This lack of methodological rigour and high risk of bias made it difficult to interpret the findings of this review. Overall, results suggest that parenting interventions may slightly improve parent‐child relationships but have a small, unimportant effect on parenting skills. Psychological interventions may help some women stop smoking in pregnancy, and may have small benefits on parents&#039; relationships and parenting skills. A financial empowerment programme may slightly worsen depression symptoms. While potential beneficial effects were small, the importance of a positive effect in a small number of parents must be considered when making treatment and care decisions. There is a need for further high‐quality research into effective strategies for this population.
AU  - Jones,
AU  - K.
AU  - A.
AU  - Freijah,
AU  - I.
AU  - Brennan,
AU  - S.
AU  - E.
AU  - McKenzie,
AU  - J.
AU  - E.
AU  - Bright,
AU  - T.
AU  - M.
AU  - Fiolet,
AU  - R.
AU  - Kamitsis,
AU  - I.
AU  - Reid,
AU  - C.
AU  - Davis,
AU  - E.
AU  - Andrews,
AU  - S.
AU  - Muzik,
AU  - M.
AU  - Segal,
AU  - L.
AU  - Herrman,
AU  - H.
AU  - Chamberlain,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD014874.pub2
L1  - internal-pdf://3896080926/Jones_et_al-2023-Cochrane_Database_of_Systemat.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions from pregnancy to two years after birth for parents experiencing complex post-traumatic stress disorder and/or with childhood experience of maltreatment
ER  -
TY  - JOUR
AB  - OBJECTIVE: 
To map the effect of motor-based interventions on motor skills in children with ADHD. 

METHOD: 
A systematic literature search was performed in Pubmed, Web of Science, and the SCOPUS database (last search: October 30th 2022). Methodological quality was assessed using the PEDro-scale and the quality of evidence was determined with the GRADE-method. Meta-analysis was performed when at least five studies were available. 

RESULTS: 
Thirteen studies (7 RCTs) satisfied the inclusion criteria, five of which were eligible for meta-analysis. Only one of the included studies reached the low risk of bias threshold. Comparing different motor-based interventions to any non-motor control intervention showed large motor skill improvements (SMD = 1.46; 95% CI = [1.00;1.93]; I2 = 47.07%). The most effective type of motor-based intervention and the optimal treatment parameters could not be determined yet. 

CONCLUSION: 
Motor-based interventions in general seem to improve motor skills in children with ADHD. Additional RCTs are needed to increase current low GRADE confidence.
AN  - 36635879
AU  - Kleeren,
AU  - L.
AU  - Hallemans,
AU  - A.
AU  - Hoskens,
AU  - J.
AU  - Klingels,
AU  - K.
AU  - Smits-Engelsman,
AU  - B.
AU  - Verbecque,
AU  - E.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/10870547221146244
L1  - internal-pdf://3283464074/10870547221146244.cleaned.pdf
PY  - 2023
SP  - 354-367
T2  - Journal of Attention Disorders
TI  - A Critical View on Motor-based Interventions to Improve Motor Skill Performance in Children With ADHD: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36635879
VL  - 27
ER  -
TY  - JOUR
AB  - Gambling disorder in youth is an emerging public health problem, with adolescents and young adults constituting a vulnerable age group for the development of gambling-related problems. Although research has been conducted on the risk factors for gambling disorder, very few rigorous studies can be found on the efficacy of preventive interventions in young people. The aim of this study was to provide best practice recommendations for the prevention of disordered gambling in adolescents and young adults. We reviewed and synthesized the results of existing RCTs and quasi-experimental studies covering nonpharmacological prevention programs for gambling disorder in young adults and adolescents. We applied the PRISMA 2020 statement and guidelines to identify 1483 studies, of which 32 were included in the systematic review. All studies targeted the educational setting, i.e., high school and university students. Most studies followed a universal prevention strategy, that particularly targeted adolescents, and an indicated prevention strategy for university students. The reviewed gambling prevention programs generally showed good results in terms of reducing the frequency and severity of gambling, and also regarding cognitive variables, such as misconceptions, fallacies, knowledge, and attitudes towards gambling. Finally, we highlight the need to develop more comprehensive prevention programs that incorporate rigorous methodological and assessment procedures before they are widely implemented and disseminated.
AN  - 36981602
AU  - Monreal-Bartolome,
AU  - A.
AU  - Barcelo-Soler,
AU  - A.
AU  - Garcia-Campayo,
AU  - J.
AU  - Bartolome-Moreno,
AU  - C.
AU  - Cortes-Montavez,
AU  - P.
AU  - Acon,
AU  - E.
AU  - Huertes,
AU  - M.
AU  - Lacasa,
AU  - V.
AU  - Crespo,
AU  - S.
AU  - Lloret-Irles,
AU  - D.
AU  - Sordo,
AU  - L.
AU  - Clotas
AU  - Bote,
AU  - C.
AU  - Puigcorbe,
AU  - S.
AU  - Lopez-Del-Hoyo,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph20064691
L1  - internal-pdf://1683960458/ijerph-20-04691.cleaned.pdf
PY  - 2023
SP  - 07
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Preventive Gambling Programs for Adolescents and Young Adults: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36981602
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-14-00156/article_deploy/ijerph-14-00156.pdf?version=1486465342
VL  - 20
ER  -
TY  - JOUR
AB  - **Purpose:** 
Depression disorder is the most commonly diagnosed type of mental illness among youths. Although a plethora of evidence suggests a positive relationship between exercise and lower levels of depression in youths, the findings regarding the variation in magnitude of this relationship are inconclusive with respect to the preventive and therapeutic effects of different types of exercise. This network meta-analysis aimed to determine the best type of exercise for the treatment and prevention of depression in youths. 

**Methods:** 
A comprehensive search of databases, including PubMed, EMBASE, The Cochrane Library, Web of Science, PsychINFO, ProQuest, Wanfang, and CNKI, was conducted to identify relevant research on exercise interventions for depression in youth populations. The risk of bias in the included studies was evaluated using Cochrane Review Manager 5.4 according to the Cochrane Handbook 5.1.0 Methodological Quality Evaluation Criteria. The network meta-analysis was performed using STATA 15.1 to calculate the standardized mean difference (SMD) of all concerned outcomes. The node-splitting method was used to test the local inconsistency of the network meta-analysis. Funnel plots were used to evaluate the potential impact of bias in this study. 

**Result:** 
Utilizing data extracted from 58 studies (10 countries, 4,887 participants), we found that for depressed youths, exercise is significantly better than usual care in reducing anxiety (SMD = -0.98, 95% CI [-1.50, -0.45]). For non-depressed youths, exercise is significantly better than usual care in reducing anxiety (SMD = -0.47, 95% CI [ -0.66, -0.29]). In the treatment of depression, resistance exercise (SMD = -1.30, 95% CI [ -1.96, -0.64]), aerobic exercise (SMD = -0.83, 95% CI [-1.10 -0.72]), mixed exercise (SMD = -0.67, 95% CI [-0.99, -0.35]), and mind-body exercise (SMD = -0.61, 95% CI [-0.84, -0.38]) all showed significant efficacy over usual care. For the prevention of depression, resistance exercise (SMD = -1.18, 95% CI [-1.65, -0.71]), aerobic exercise (SMD = -0.72, 95% CI [-0.98, -0.47]), mind-body exercise (SMD = -0.59, 95% CI [-0.93, -0.26]), and mixed exercise (SMD = -1.06, 95% CI [-1.37 to -0.75]) were all significantly effective compared to usual care. According to the test of the surface under the cumulative ranking score (SUCRA), the ranking of exercises for the treatment of depression in depressed youths is as follows: resistance exercise (94.9%) &gt; aerobic exercise (75.1%) &gt; mixed exercise (43.8%) &gt; mind-body exercise (36.2%) &gt; usual care (0%). For the prevention of depression in non-depressed youths, resistance exercise (90.3%) &gt; mixed exercise (81.6%) &gt; aerobic exercise (45.5%) &gt; mind-body exercise (32.6%) &gt; usual care (0%). Resistance exercise thus had the best comprehensive effect on both the treatment and prevention of depression in youths (clusterank value = 1914.04). Subgroup analyses show that a frequency of 3-4 times per week, a duration of 30-60 min, and a length of more than 6 weeks were found to be the most effective interventions for depression (P &gt; 0.001). 

**Conclusion:** 
This study provides compelling evidence that exercise is a viable intervention for improving depression and anxiety in young individuals. In addition, the study emphasizes the importance of selecting the appropriate type of exercise to optimize treatment and prevention. Specifically, the results suggest that resistance exercise, performed 3-4 times per week, with sessions lasting 30-60 min and a length of more than 6 weeks, yields optimal results for the treatment and prevention of depression in young individuals. These findings have significant implications for clinical practice, particularly given the challenges associated with implementing effective interventions and the economic burden of treating and preventing depression in young people. However, it is worth noting that additional head-to-head studies are necessary to confirm these findings and strengthen the evidence base. Nevertheless, this study provides valuable insights into the role of exercise as a potential treatment and preventative measure for depression in young people. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=374154, identifier: 374154.
AN  - 37333923
AU  - Zhang,
AU  - Y.
AU  - Li,
AU  - G.
AU  - Liu,
AU  - C.
AU  - Guan,
AU  - J.
AU  - Zhang,
AU  - Y.
AU  - Shi,
AU  - Z.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyt.2023.1199510
L1  - internal-pdf://2145381078/pdf.cleaned (5).pdf
PY  - 2023
SP  - 1199510
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Comparing the efficacy of different types of exercise for the treatment and prevention of depression in youths: a systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37333923
VL  - 14
ER  -
TY  - JOUR
AB  - There is a high prevalence rate of co-occurring alcohol use and mental health problems in young people. This is associated with adverse outcomes and poses a substantial public health concern. We identified and synthesized evidence on the effectiveness of family-involved interventions in reducing alcohol use and mental health problems in young people aged 12-17. Seven databases were searched from inception to January 2023. Data from 19 articles reporting on 14 trials were pooled through random-effects meta-analysis for each outcome using Review Manager 5.3. Pooled estimates resulted in non-significant findings for alcohol use (SMD -0.60; 95% CI -1.63 to 0.42; p = 0.25; 6 trials; 537 participants), internalizing symptoms (SMD -0.13; 95% CI -0.37 to 0.10; p = 0.27), externalizing symptoms (SMD -0.26; 95% CI -0.66 to 0.15; p = 0.22) and substance use (SMD -0.33; 95% CI -0.72 to 0.06; p = 0.10). In contrast, significant intervention effects were identified for the mechanism of change, family conflict (SMD -0.30; 95% CI -0.51 to -0.09; p = 0.005). Consequently, addressing family functioning may not be sufficient in reducing co-occurring alcohol use and mental health problems. Non-significant intervention effects could be due to a lack of content addressing the relationship between alcohol use and mental health problems. Future intervention development could explore whether to incorporate such content and how best to involve the family.
AN  - 37835160
AU  - Geijer-Simpson,
AU  - E.
AU  - Kaner,
AU  - E.
AU  - Lingam,
AU  - R.
AU  - McArdle,
AU  - P.
AU  - McGovern,
AU  - R.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/ijerph20196890
L1  - internal-pdf://0498735388/Geijer.pdf
PY  - 2023
SP  - 06
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Effectiveness of Family-Involved Interventions in Reducing Co-Occurring Alcohol Use and Mental Health Problems in Young People Aged 12-17: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37835160
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-14-00156/article_deploy/ijerph-14-00156.pdf?version=1486465342
VL  - 20
ER  -
TY  - JOUR
AB  - **Background** 
Behavioural parent training is an evidence-based intervention for children with attention-deficit/hyperactivity disorder (ADHD), but little is known about the extent to which initial benefits are maintained. 

**Aims** 
This meta-analytic review investigated longer-term (i.e., more than 2 months post-intervention) child and parental outcomes of behavioural parent training for children with ADHD. 

**Materials &amp; Methods** 
We searched for randomized controlled trials and examined ADHD symptoms, behavioural problems, positive parenting, negative parenting, parenting sense of competence, parent-child relationship quality, and parental mental health as outcomes. We included 27 studies (31 interventions; 217 effect sizes), used multilevel random-effects meta-analyses for between- and within-group comparisons (pre-intervention to follow-up and post-intervention to follow-up), and explored twelve predictors of change. 

**Results** 
Between pre-intervention and follow-up (M = 5.3 months), we found significant small-to-moderate between-group effects of the intervention on ADHD symptoms, behavioural problems, positive parenting, parenting sense of competence and parent-child relationship quality. Within-group findings show sustained improvements in the intervention conditions for all outcome domains. There were few significant changes from post-intervention to follow-up. Additionally, the large majority of the individual effect sizes indicated sustained outcomes from post-intervention to follow-up. There were seven significant predictors of change in child outcomes, including stronger reductions in ADHD symptoms of girls and behaviour problems of younger children. In contrast with some meta-analyses on short-term effects, we found no differences between masked and unmasked outcomes on ADHD symptoms at follow-up. 

**Discussion &amp; Conclusion**
We conclude that behavioural parent training has longer-term benefits for children&#039;s ADHD symptoms and behavioural problems, and for positive parenting behaviours, parenting sense of competence and quality of the parent-child relationship. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2024-07041-001
AU  - Doffer,
AU  - D.
AU  - P.
AU  - Dekkers,
AU  - T.
AU  - J.
AU  - Hornstra,
AU  - R.
AU  - van
AU  - der
AU  - Oord,
AU  - S.
AU  - Luman,
AU  - M.
AU  - Leijten,
AU  - P.
AU  - Hoekstra,
AU  - P.
AU  - J.
AU  - van
AU  - den
AU  - Hoofdakker,
AU  - B.
AU  - J.
AU  - Groenman,
AU  - A.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/jcv2.12196
L1  - internal-pdf://4186042712/Doffer-2023-Sustained improvements by behaviou.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Jcpp Advances
TI  - Sustained improvements by behavioural parent training for children with attention-deficit/hyperactivity disorder: A meta-analytic review of longer-term child and parental outcomes
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2024-07041-001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcv2.12196?download=true
ER  -
TY  - JOUR
AB  - **Background:** 
Attention problems are one of the core symptoms of Attentiondeficit/hyperactivity disorder (ADHD) in children. Previous studies have shown that physical activity intervention has a positive impact on executive function in children and adolescents with ADHD, but there is limited research on attention problems in school-aged children with ADHD. There are still uncertainties about the appropriate physical activity interventions to improve attention problems in this population. This study conducted a Meta-analysis of randomized controlled trials (RCTs) related to physical activity intervention for attention problems in school-aged children with ADHD, providing a certain reference for precise intervention in attention problems for this population.

**Methods:** 
We systematically searched the following databases up to October 2022: PubMed, Embase, Web of Science, and Cochrane Library, to identify RCTs that investigated the effects of physical activity interventions on children with ADHD. Two investigators independently conducted literature screening, extraction, and quality assessment. We performed a meta-analysis using Stata 15.1.

**Results:** 
In total, we included 10 studies in this meta-analysis. The results indicated that physical activity intervention had a moderate effect in improving attention problems in school-aged children with ADHD (SMD = &minus;0.48, 95% CI: 0.85, &minus;0.07, p &lt; 0.05). Furthermore, subgroup analysis showed that the effect of physical activity intervention was moderated by intervention type, frequency, and period, rather than the physical activity environment or single intervention time.

**Conclusion:** 
Our study suggests that cognitively engaging exercise is more effective in improving attention problems in school-aged children with ADHD. Specifically, when cognitive-engaging exercise is used as the type of physical activity and the intervention frequency is less than 3 times per week, with an intervention period of less than weeks, it is most beneficial for improving attention problems in school-aged children with ADHD. However, we should also consider individual differences in children with respect to their ADHD symptoms and accurately evaluate each child&rsquo;s specific symptoms before intervention.

Systematic Review Registration: identifier (CRD42022363255).
AN  - 37576338
AU  - Li,
AU  - D.
AU  - Li,
AU  - L.
AU  - Zang,
AU  - W.
AU  - Wang,
AU  - D.
AU  - Miao,
AU  - C.
AU  - Li,
AU  - C.
AU  - Zhou,
AU  - L.
AU  - Yan,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fphys.2023.1189443
L1  - internal-pdf://2677444351/Li-2023-Effect of physical activity on attenti.pdf
PY  - 2023
SP  - 1189443
T2  - Frontiers in Physiology
TI  - Effect of physical activity on attention in school-age children with ADHD: a systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37576338
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10415683/pdf/fphys-14-1189443.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder in children and adolescents. Recent studies show that video games have great potential for the treatment and rehabilitation of ADHD patients. The aim of the present review is to systematically review the scientific literature on the relationship between video games and ADHD, focusing on adherence to treatment, frequency of the intervention, and the long-term follow-up of video games in children and adolescents with ADHD. 

METHODS: The preferred reporting items for systematic reviews and meta-analyses guidelines were adopted. The review protocol was registered in PROSPERO database. We searched in three databases, PubMed, Medline, and Web of Science to identify studies examining the association between video game interventions in ADHD patients. 

RESULTS: A total of 18 empirical studies met the established inclusion criteria. The results showed that video games-based interventions can be used to improve ADHD symptoms and display high adherence to treatment. In addition, in the studies reviewed, the most common intervention frequency is 30 min three to five times per week. However, there is little evidence from studies with video games showing long-term effects in patients with ADHD. 

CONCLUSION: Video games are useful and effective interventions that can complement traditional treatments in patients with ADHD.
AN  - 37743605
AU  - Caselles-Pina,
AU  - L.
AU  - Sujar,
AU  - A.
AU  - Quesada-Lopez,
AU  - A.
AU  - Delgado-Gomez,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/brb3.3265
L1  - internal-pdf://2401365500/Caselles-Pina-2023-Adherence, frequency, and l.pdf
PY  - 2023
SP  - e3265
T2  - Brain and Behavior
TI  - Adherence, frequency, and long-term follow-up of video game-based treatments in patients with attention-deficit/hyperactivity disorder: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37743605
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/brb3.3265?download=true
ER  -
TY  - JOUR
AB  - **Background**
Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed and treated psychiatric disorders in childhood. Typically, children and adolescents with ADHD find it difficult to pay attention and they are hyperactive and impulsive. Methylphenidate is the psychostimulant most oſten prescribed, but the evidence on benefits and harms is uncertain. This is an update of our comprehensive systematic review on benefits and harms published in 2015.

**Objectives** 
To assess the beneficial and harmful effects of methylphenidate for children and adolescents with ADHD. Search methods
We searched CENTRAL, MEDLINE, Embase, three other databases and two trials registers up to March 2022. In addition, we checked reference lists and requested published and unpublished data from manufacturers of methylphenidate. 

**Selection criteria**
We included all randomised clinical trials (RCTs) comparing methylphenidate versus placebo or no intervention in children and adolescents aged 18 years and younger with a diagnosis of ADHD. The search was not limited by publication year or language, but trial inclusion required that 75% or more of participants had a normal intellectual quotient (IQ &gt; 70). We assessed two primary outcomes, ADHD symptoms and serious adverse events, and three secondary outcomes, adverse events considered non-serious, general behaviour, and quality of life.

**Data collection and analysis**
Two review authors independently conducted data extraction and risk of bias assessment for each trial. Six review authors including two review authors from the original publication participated in the update in 2022. We used standard Cochrane methodological procedures. Data from parallel-group trials and first-period data from cross-over trials formed the basis of our primary analyses. We undertook separate analyses using end-of-last period data from cross-over trials. We used Trial Sequential Analyses (TSA) to control for type I (5%) and type II (20%) errors, and we assessed and downgraded evidence according to the GRADE approach.

**Main results**
We included 212 trials (16,302 participants randomised); 55 parallel-group trials (8104 participants randomised), and 156 cross-over trials (8033 participants randomised) as well as one trial with a parallel phase (114 participants randomised) and a cross-over phase (165 participants randomised). The mean age of participants was 9.8 years ranging from 3 to 18 years (two trials from 3 to 21 years). The malefemale ratio was 3:1. Most trials were carried out in high-income countries, and 86/212 included trials (41%) were funded or partly funded by the pharmaceutical industry. Methylphenidate treatment duration ranged from 1 to 425 days, with a mean duration of 28.8 days. Trials compared methylphenidate with placebo (200 trials) and with no intervention (12 trials). Only 165/212 trials included usable data on one or more outcomes from 14,271 participants.

Of the 212 trials, we assessed 191 at high risk of bias and 21 at low risk of bias. If, however, deblinding of methylphenidate due to typical adverse events is considered, then all 212 trials were at high risk of bias.

Primary outcomes: methylphenidate versus placebo or no intervention may improve teacher-rated ADHD symptoms (standardised mean difference (SMD) &minus;0.74, 95% confidence interval (CI) &minus;0.88 to &minus;0.61; I2 = 38%; 21 trials; 1728 participants; very low-certainty evidence). This corresponds to a mean difference (MD) of &minus;10.58 (95% CI &minus;12.58 to &minus;8.72) on the ADHD Rating Scale (ADHD-RS; range 0 to 72 points). The minimal clinically relevant difference is considered to be a change of 6.6 points on the ADHD-RS. Methylphenidate may not affect serious adverse events (risk ratio (RR) 0.80, 95% CI 0.39 to 1.67; I2 = 0%; 26 trials, 3673 participants; very low-certainty evidence). The TSA-adjusted intervention effect was RR 0.91 (CI 0.31 to 2.68).

Secondary outcomes: methylphenidate may cause more adverse events considered non-serious versus placebo or no intervention (RR 1.23, 95% CI 1.11 to 1.37; I2 = 72%; 35 trials 5342 participants; very low-certainty evidence). The TSA-adjusted intervention effect was RR 1.22 (CI 1.08 to 1.43). Methylphenidate may improve teacher-rated general behaviour versus placebo (SMD &minus;0.62, 95% CI &minus;0.91 to &minus;0.33; I2 = 68%; 7 trials 792 participants; very low-certainty evidence), but may not affect quality of life (SMD 0.40, 95% CI &minus;0.03 to 0.83; I2 = 81%; 4 trials, 608 participants; very low-certainty evidence).

**Authors&#039; conclusions**
The majority of our conclusions from the 2015 version of this review still apply. Our updated meta-analyses suggest that methylphenidate versus placebo or no-intervention may improve teacher-rated ADHD symptoms and general behaviour in children and adolescents with ADHD. There may be no effects on serious adverse events and quality of life. Methylphenidate may be associated with an increased risk of adverse events considered non-serious, such as sleep problems and decreased appetite. However, the certainty of the evidence for all outcomes is very low and therefore the true magnitude of effects remain unclear.
Due to the frequency of non-serious adverse events associated with methylphenidate, the blinding of participants and outcome assessors is particularly challenging. To accommodate this challenge, an active placebo should be sought and utilised. It may be difficult to find such a drug, but identifying a substance that could mimic the easily recognised adverse effects of methylphenidate would avert the unblinding that detrimentally affects current randomised trials.
Future systematic reviews should investigate the subgroups of patients with ADHD that may benefit most and least from methylphenidate. This could be done with individual participant data to investigate predictors and modifiers like age, comorbidity, and ADHD subtypes.
AU  - Storebø,
AU  - O.
AU  - J.
AU  - Storm,
AU  - M.
AU  - R.
AU  - O.
AU  - Ribeiro,
AU  - J.
AU  - P.
AU  - Skoog,
AU  - M.
AU  - Groth,
AU  - C.
AU  - Callesen,
AU  - H.
AU  - E.
AU  - Schaug,
AU  - J.
AU  - P.
AU  - Rasmussen,
AU  - P.
AU  - D.
AU  - Huus,
AU  - C.-M.
AU  - L
AU  - Zwi,
AU  - M.
AU  - Kirubakaran,
AU  - R.
AU  - Simonsen,
AU  - E.
AU  - Gluud,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD009885.pub3
L1  - internal-pdf://1704870458/Storeb-_et_al-2023-Cochrane_Database_of_System.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD)
ER  -
TY  - JOUR
AB  - **BACKGROUND:**

The efficacy of structured physical exercise (SPE) has been examined in empirical studies to treat attention deficit hyperactivity disorder (ADHD). This review aimed (i) to systematically review and quantify the effects of SPE on ADHD symptomology and executive function (primary outcomes) and on physical health, physical fitness and mental health issues (secondary outcomes) in children/adolescents with ADHD; (ii) to evaluate the study quality and explore moderation of the effects of SPE; and (iii) to summarize the design of SPE interventions. 

**METHODS:**

An extensive literature search in the databases of PubMed, Web of Science and EBSCOhost was conducted to identify eligible intervention studies for meta-analysis. A descriptive account of the features of the studies is provided, including assessment of risk/quality (ROB-2/ROBINS-I). Standardized mean difference (SMD) with 95% confidence intervals (CIs) were calculated with random effects models to compare post-intervention effects. 

**RESULTS:**

 A total of 18 studies were included in the review. The majority of the studies examined the effects of SPE lasting for 3-12 weeks. Assessment of bias/quality indicated half of the included studies as high quality. The meta-analysis (pooled n = 627) revealed that SPE had a positive effect on primary and secondary outcomes, that is, inattention (SMD = -1.79), executive function (SMD = 2.19), physical fitness (SMD = 1.39) and mental health issues (SMD = -0.89). Subgroup analysis showed that long-term practice of SPE, featured/tailored SPE, non-Chinese participants, taking methylphenidate and study with low quality had larger effects. 

**CONCLUSIONS:**
 
There is emerging evidence that SPE is a promising option to enhance symptom management and physical/mental health in children/adolescents with ADHD.
AN  - 37433667
AU  - Sun,
AU  - F.
AU  - Fang,
AU  - Y.
AU  - Chan,
AU  - C.
AU  - K.
AU  - M.
AU  - Poon,
AU  - E.
AU  - T.
AU  - C.
AU  - Chung,
AU  - L.
AU  - M.
AU  - Y.
AU  - Or,
AU  - P.
AU  - P.
AU  - L.
AU  - Chen,
AU  - Y.
AU  - Cooper,
AU  - S.
AU  - B.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/cch.13150
L1  - internal-pdf://2207199165/Sun-2023-Structured physical exercise interven.pdf
PY  - 2023
SP  - 11
T2  - Child: Care, Health &amp; Development
TI  - Structured physical exercise interventions and children and adolescents with attention deficit hyperactivity disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37433667
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cch.13150?download=true
VL  - 11
ER  -
TY  - JOUR
AB  - OBJECTIVE: Complementary and alternative treatments (CATs) for ADHD have proliferated over the past decade; however, their safety and efficacy remain uncertain. We completed a systematic review and meta-analyses across CAT domains. 

METHODS: Systematic search and data extraction identified randomized controlled trials for pediatric ADHD (ages 3-19 years) that included probably blind ADHD symptom outcome measures. We evaluated basic (RCT of a CAT compared with sham/placebo, attention/active control, treatment as usual, and waitlist control), complementary (RCTs comparing an evidence-based treatment with a CAT and the same evidence-based treatment), and alternative (evidence-based treatment to CAT) efficacy. Random-effect meta-analyses were conducted when at least 3 blinded studies were identified for a specific CAT domain. 

RESULTS: Eighty-seven of 2253 nonduplicate screened manuscripts met inclusion criteria. No study reported significantly greater adverse effects for CATs than controls; naturopathy reported fewer adverse effects than evidence-based treatments but did not demonstrate basic efficacy. In the systematic review of basic efficacy, evidence of effectiveness was mixed but replicated previous evidence for the possible efficacy of cognitive training, neurofeedback, and essential fatty acid supplementation for certain patients. With respect to alternative and complementary efficacy, no CAT outperformed or enhanced evidence-based treatments (stimulant medications and behavioral therapy) when replication was required. Individual meta-analyses indicated that cognitive training was the only CAT that demonstrated overall basic efficacy (SMD = 0.216; p = 0.032). 

CONCLUSION: Clinicians may cautiously recommend (but monitor) cognitive training when evidence-based treatments are not feasible or effective for a patient. Additional studies are needed to further understand the potential of CAT domains. Copyright &copy; 2023 Wolters Kluwer Health, Inc. All rights reserved.
AN  - 37084312
AU  - Zulauf-McCurdy,
AU  - C.
AU  - A.
AU  - LaCount,
AU  - P.
AU  - A.
AU  - Shelton,
AU  - C.
AU  - R.
AU  - Morrow,
AU  - A.
AU  - S.
AU  - Zhao,
AU  - X.
AU  - A.
AU  - Russell,
AU  - D.
AU  - Sibley,
AU  - M.
AU  - H.
AU  - Arnold,
AU  - L.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/DBP.0000000000001184
L1  - internal-pdf://2823195027/McCurdy_2023.pdf
PY  - 2023
SP  - 21
T2  - Journal of Developmental &amp; Behavioral Pediatrics
TI  - Systematic Review and Meta-Analyses: Safety and Efficacy of Complementary and Alternative Treatments for Pediatric Attention-Deficit/Hyperactivity Disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37084312
VL  - 21
ER  -
TY  - JOUR
AB  - Cognitive behavioral therapy (CBT) is widely recognized as an effective treatment for obsessive-compulsive disorder (OCD). However, few patients are able to receive CBT. Internet-based CBT (ICBT) may be able to overcome this problem. 

In this study, we aimed to compare the efficacy of CBT, therapist-guided ICBT (TG-ICBT), unguided ICBT (UG-ICBT), and none therapist-guided ICBT (NTG-ICBT) by a network meta-analysis. The primary outcome was the mean change in OCD severity measured by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) or the Children&#039;s Yale-Brown Obsessive Compulsive Scale (CY-BOCS). The secondary outcomes included the severity of depressive symptoms, side effects, and cost-effectiveness. 

A total of 25 trials with 1642 participants were included. We found that the efficacy of CBT was superior to that of TG-ICBT. The mean improvement in Y-BOCS/CY-BOCS scores was higher in CBT group than in UG-ICBT group, but this difference was not statistically significant. The efficacy did not differ significantly between TG-ICBT and UG-ICBT. CBT, TG-ICBT, and UG-ICBT were all more effective than the psychological placebo, waiting list, and pill placebo. In terms of efficacy, CBT combined with drug therapy was better than CBT, TG-ICBT, and UG-ICBT. Sensitivity analyses supported these findings. 

Based on the current evidence, we recommend TG-ICBT when CBT is not available. However, it is undeniable that UG-ICBT also has the potential to be an effective alternative to CBT. More evidence is needed to support this possibility.
AN  - 37907037
AU  - Zhang,
AU  - W.
AU  - Yang,
AU  - W.
AU  - Ruan,
AU  - H.
AU  - Gao,
AU  - J.
AU  - Wang,
AU  - Z.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jpsychires.2023.10.025
L1  - internal-pdf://3647153145/Zhang_2023.pdf
PY  - 2023
SP  - 140-148
T2  - Journal of Psychiatric Research
TI  - Comparison of internet-based and face-to-face cognitive behavioral therapy for obsessive-compulsive disorder: A systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=37907037
UR  - https://www.sciencedirect.com/science/article/pii/S0022395623004636?via%3Dihub
VL  - 168
ER  -
TY  - JOUR
AB  - Anxiety disorders are the most prevalent mental health issues in childhood, yet most children do not receive treatment. With recent advances in technology, a growing number of digital anxiety interventions are becoming accessible. This study is the first meta-analysis to evaluate the effectiveness and usefulness of digital cognitive-behavioral anxiety interventions for individuals under the age of 18. Five electronic databases (PsycNET, Web of Science, Science Direct, Pub Med, SAGE Journals.) were systematically searched in 2021. Inclusion criteria were: randomized control trials with a wait list no treatment control, standalone to blended care with minimal therapist involvement, diagnosed anxiety disorder or elevated levels of anxiety, outcome anxiety levels had to be assessed by a clinician, or the patients themselves by a validated anxiety measure. We assessed and controlled for publication bias, and considered the risk of bias using the Cochrane risk-of-bias tool. Eighteen studies were found eligible, which examined 1290 participants in total. Pooled effect sizes using a random-effects model yielded low overall effect for self-ratings (g = 0.28, k = 18, p &lt; 0.001, 95% CI [0.14; 0.41]), and medium effect for ratings of clinicians (g = 0.66, k = 13, p &lt; 0.001, 95% CI [0.50; 0.80]) as well as for parental report (g = 0.49, k = 16, p &lt; 0.001, 95% CI [0.29; 0.69]). We found that the effects were homogenous across studies. Further examining potential moderating factors of treatment efficacy is needed in future research, as well as conducting studies that compare traditional methods of care to their digital counterparts. Digital interventions could contribute to the well-being of children regardless of age, minimizing therapist involvement. We conclude that digital cognitive-behavioral interventions may provide an accessible, cost-effective, and scalable anxiety treatment option for children and adolescents. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2024-37996-001
AU  - Csirmaz,
AU  - L.
AU  - Nagy,
AU  - T.
AU  - Vikor,
AU  - F.
AU  - Kasos,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10935-023-00760-0
L1  - internal-pdf://0247735934/Csirmaz-2023-Cognitive behavioral digital inte.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Journal of Prevention
TI  - Cognitive behavioral digital interventions are effective in reducing anxiety in children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2024-37996-001
UR  - https://link.springer.com/content/pdf/10.1007/s10935-023-00760-0.pdf
ER  -
TY  - JOUR
AB  - **INTRODUCTION**
Suicidality among young people is a significant societal issue. The current study conducted a meta-analysis of community and clinical interventions targeting suicide attempts, self-harm, and suicidal ideation in adolescents. 

**METHOD**
Interventions targeting suicide attempts, self-harm and suicidal ideation were identified by searching PsychINFO, Medline, CINAHL and Embase in line with the PRISMA statement. Study quality was determined using a risk of bias tool. Meta-analyses examined the efficacy of the interventions. Effect sizes were calculated for suicidal ideation data (continuous data) using Hedge&#039;s g for standardised mean differences. Suicide attempts and self-harm (dichotomous data) were calculated using odds ratios (ORs). 

**RESULTS**
Seventeen RCTs were included in the meta-analysis. No significant differences were found between treatment and control groups on measures of suicide attempts or self-harm. A small effect-size was observed on measures of suicidal ideation (g = 0.47). A secondary meta-analysis investigated change over time in treatment as usual conditions, finding significant large effect-sizes for suicide attempts (OR = 18.67), self-harm (OR = 12.77), and suicidal ideation (g = 0.86). 

**LIMITATIONS**
The methodological decision to focus on specific outcomes over a broad definition of self-harm excluded some papers, which have been included in other reviews. It is unlikely to have significantly affected the overall results. The review was not preregistered. 

**CONCLUSIONS**
These twin findings highlight the importance overcoming the methodological difficulty of discerning effective interventions during a period of baseline improvement. We suggest that future trials should move away from broadly addressing &quot;suicidality/self-harm&quot; and encourage a greater targeting of at-risk individuals.
AN  - 36758338
AU  - Gaynor,
AU  - K.
AU  - O&#039;Reilly,
AU  - M.
AU  - D.
AU  - Redmond,
AU  - D.
AU  - Nealon,
AU  - C.
AU  - Twomey,
AU  - C.
AU  - Hennessy,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.comppsych.2023.152374
L1  - internal-pdf://0998947357/1-s2.0-S0010440X23000111-main.cleaned.pdf
PY  - 2023
SP  - 152374
T2  - Comprehensive Psychiatry
TI  - A meta-analysis of targeted interventions for reducing suicide-related behaviour and ideation in adolescents: Implications for trial design
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36758338
VL  - 122
ER  -
TY  - JOUR
AB  - While there are a number of systematic reviews on school-based mental health programs, there appears to be heterogeneity in their overall findings and conclusions, possibly due to the tendency to combine evidence from primary school and high school programs. To investigate the evidence for the effectiveness of targeted (for specific groups) and universal (for all students) mental health programs delivered in secondary schools, a systematic review of systematic reviews was conducted. A systematic search for reviews published from 2015 included outcomes for depression and anxiety-the most common mental health conditions-and quality appraisal of original studies in majority secondary school settings. A total of 395 references were screened and 14 systematic reviews were included. Of reviews that were assessed in full, most were excluded for not clearly separating studies in secondary school settings from primary school settings. Findings were generally positive but heterogenous in terms of quality and long-term outcomes. Interventions were mainly based on cognitive behavioural therapy (CBT), with results showing that targeted interventions are generally effective in the short-term for both anxiety and depression, while universal programs may be effective in some situations, typically in the short term and when programs were CBT-based; where reviews focused on universal resilience programs there were no significant effects. The overview shows a need for systematic reviews focused on secondary school settings, which consider contextual and individual factors that can influence the implementation and effectiveness of programs.
AN  - WOS:000978845400001
AU  - Zbukvic,
AU  - I.
AU  - McKay,
AU  - S.
AU  - Cooke,
AU  - S.
AU  - Anderson,
AU  - R.
AU  - Pilkington,
AU  - V.
AU  - McGillivray,
AU  - L.
AU  - Bailey,
AU  - A.
AU  - Purcell,
AU  - R.
AU  - Tye,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40894-023-00211-1
L1  - internal-pdf://3541070914/Zbukvic-2023-Evidence for Targeted and Univers.pdf
PY  - 2023
SP  - 21
T2  - Adolescent Research Review
TI  - Evidence for Targeted and Universal Secondary School-Based Programs for Anxiety and Depression: An Overview of Systematic Reviews
UR  - &lt;Go to ISI&gt;://WOS:000978845400001
UR  - https://link.springer.com/content/pdf/10.1007/s40894-023-00211-1.pdf
ER  -
TY  - JOUR
AB  - **Background**
This systematic review and meta-analysis examined the efficacy of Cognitive Bias Modification of Interpretation (CBM-I) to reduce hostile interpretation bias and aggressive behavior.

**Methods**
We searched PsycINFO, PubMed, Embase, Web of Science, and Cochrane Library databases up until January 1, 2023, and assessed risk of bias using Cochrane&#039;s risk of bias tool (RoB 2). We used multi-level meta-analysis to synthesize effect sizes.

**Results**
Fourteen articles including 16 randomized studies met the inclusion criteria, yielding data from 1449 participants. CBM-I had medium effects on hostile interpretation (d = -0.62, p &lt; .001) and benign interpretation (d = 0.71, p &lt; .001), and a small effect on aggressive behavior (d = -0.28, p = .017). However, effects on interpretation bias were significant only for measures that were similar to the training method, suggesting that CBM-I effects do not generalize beyond the training task. Moreover, effects on aggressive behavior were significant only for self-reported aggression, suggesting demand effects. Effects on non-self-reported aggression were small and even zero after excluding one study with an exceptionally large effect size.

**Conclusion**
There currently is insufficient evidence to use CBM-I as a treatment component to reduce aggressive behavior.
AN  - WOS:001044209400001
AU  - AlMoghrabi,
AU  - N.
AU  - Verhoef,
AU  - R.
AU  - E.
AU  - J.
AU  - Smeijers,
AU  - D.
AU  - Huijding,
AU  - J.
AU  - van
AU  - Dijk,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s10608-023-10415-3
L1  - internal-pdf://3584223983/AlMoghrabi-2023-The Effects of Cognitive Bias.pdf
PY  - 2023
SP  - 20
T2  - Cognitive Therapy and Research
TI  - The Effects of Cognitive Bias Modification on Hostile Interpretation Bias and Aggressive Behavior: A Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001044209400001
UR  - https://link.springer.com/article/10.1007/s10608-023-10415-3
UR  - https://link.springer.com/content/pdf/10.1007/s10608-023-10415-3.pdf
ER  -
TY  - JOUR
AB  - **Purpose of Review**
Stand-alone digital interventions&mdash;digital interventions delivered without provider or teacher involvement&mdash;hold promise for improving access to substance use prevention services for adolescents. We conducted a systematic review and meta-analysis to determine the efficacy of stand-alone digital interventions to prevent substance use among adolescents.

**Recent Findings**
A systematic literature search yielded 35 randomized controlled trial studies. Meta-analysis revealed significant reductions in alcohol (d = 0.4, 95% CI: 0.2, 0.5, n = 27), cannabis (d = 0.2, 95% CI: 0.1, 0.4, n = 19), and tobacco (d = 0.2, 95% CI: 0.1, 0.3, n = 18) use. Interventions with booster sessions were more likely to be effective in preventing substance use (p &lt; 0.05). Interventions that offered multiple sessions yielded larger effect sizes for alcohol (0.5 vs. 0.2) and cannabis (0.3 vs. 0.2) use, and interventions that involved parents yielded larger effect sizes for alcohol use (0.7 vs. 0.2). Among studies that reported on racial/ethnic distributions, there was an extremely low representation of American Indian or Alaskan and Native Hawaiian or Other Pacific Islander groups compared to other racial/ethnic groups (Asian, Black, Hispanic, and White).

**Summary** 
Stand-alone digital interventions were effective at preventing alcohol, cannabis, and tobacco use with small but significant effect sizes among adolescents. However, studies including Native American adolescents are lacking and needed.
AN  - WOS:001044207400001
AU  - Aneni,
AU  - K.
AU  - Meyer,
AU  - J.
AU  - Funaro,
AU  - M.
AU  - C.
AU  - Pegram,
AU  - D.
AU  - Umutoni,
AU  - F.
AU  - A.
AU  - de
AU  - la
AU  - Vega,
AU  - I.
AU  - G.
AU  - Jiao,
AU  - M.
AU  - G.
AU  - Fernandes,
AU  - C.
AU  - S.
AU  - F.
AU  - Onyeaka,
AU  - H.
AU  - Baiden,
AU  - P.
AU  - Camenga,
AU  - D.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40429-023-00508-0
L1  - internal-pdf://3357142102/Aneni-2023-A Systematic Review and Meta-Analys.pdf
PY  - 2023
SP  - 378-395
T2  - Current Addiction Reports
TI  - A Systematic Review and Meta-Analysis Evaluating the Efficacy of Stand-Alone Digital Interventions to Prevent Substance Use Among Adolescents
UR  - &lt;Go to ISI&gt;://WOS:001044207400001
UR  - https://link.springer.com/article/10.1007/s40429-023-00508-0
UR  - https://link.springer.com/content/pdf/10.1007/s40429-023-00508-0.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **CONTEXT:**

Distraction therapies are widely used in emergency departments to manage pediatric pain and distress. Little is known about which distraction techniques would translate best into the prehospital environment. 

**OBJECTIVE:**

To identify emergency department-based distraction techniques for managing pain and/or distress in pediatric patients who may be suitable for the prehospital environment. DATA SOURCES: Ovid Medline, Embase, CINAHL, Cochrane library, World Health Organization Clinical Trials Registry and Google Scholar were searched from their beginning to May 2022. 

**STUDY SELECTION:**

Studies were included if they reported on: (1) distraction techniques, (2) pediatric ED patients, (3) with pain and/or distress, and (4) used interventional or observational study designs. Studies utilizing interventions not feasible in the prehospital setting were excluded. 

**DATA EXTRACTION:**

Three authors independently assessed eligibility and completed data extraction. RESULTS: The search yielded 4516 records, and 29 studies were included. Risk of bias across all studies was moderate to high. Children were 3 months to 18 years old. Digital, nondigital, and environmental distractors were tested using 12 pain and 15 distress measurement tools. No significant negative outcomes were reported. Fifteen studies reported reductions in self-reported pain and/or distress. Active, nondigital distractors most consistently reduced pain. There was insufficient evidence to support a distraction type for distress. 

**LIMITATIONS:**

The heterogeneity in study design, distractors, measurement tools, and reporting restricted statistical analysis. 

**CONCLUSIONS:**

Distraction tools that effectively reduce pediatric pain and/or distress in the ED exist and could be adapted to the prehospital environment. Further research is required to determine feasibility and effectiveness.
AN  - 37259203
AU  - Robinson,
AU  - N.
AU  - Delorenzo,
AU  - A.
AU  - Howell,
AU  - S.
AU  - Smith,
AU  - K.
AU  - Cameron,
AU  - P.
AU  - Stock,
AU  - A.
AU  - Eastwood,
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1542/peds.2022-059910
L1  - internal-pdf://1295985387/Robinson_2023_II.pdf
PY  - 2023
SP  - 01
T2  - Pediatrics
TI  - Pediatric Distraction Tools for Prehospital Care of Pain and Distress: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37259203
UR  - https://publications.aap.org/pediatrics/article/152/1/e2022059910/191426/Pediatric-Distraction-Tools-for-Prehospital-Care
VL  - 152
ER  -
TY  - JOUR
AB  - **Background:**

Melatonin prescriptions for children and adolescents have increased substantially during the last decade. Existing clinical recommendations focus on melatonin as a treatment for insomnia related to neurodevelopmental disorders. To help guide clinical decision-making, we aimed to construct a recommendation on the use of melatonin in children and adolescents aged 5-20 years with idiopathic chronic insomnia. 

**Methods:**

A systematic search for guidelines, systematic reviews and randomised controlled trials (RCT) were performed in Medline, Embase, Cochrane Library, PsycInfo, Cinahl, Guidelines International Network, Trip Database, Canadian Agency for Drugs and Technologies in Health, American Academy of Sleep Medicine, European Sleep Research Society and Scandinavian Health Authorities databases. A search for adverse events in otherwise healthy children and adolescents was also performed. The latest search for guidelines, systematic reviews, and adverse events was performed on March 18, 2023. The latest search for RCTs was performed on to February 6, 2023. The language was restricted to English, Danish, Norwegian, and Swedish. Eligible participants were children and adolescents (5-20 years of age) with idiopathic chronic insomnia, in whom sleep hygiene practices have been inadequate and melatonin was tested. There were no restrictions on dosage, duration of treatment, time of consumption, or release formula. Primary outcomes were quality of sleep, daytime functioning and serious adverse events. Secondary outcomes included total sleep time, sleep latency, awakenings, drowsiness, quality of life, all-cause dropouts, and non-serious adverse events. Outcomes were assessed at different time points to assess short-term and long-term effects. Meta-analysis was performed using inverse variance random-effects model and risk of bias was assessed using Cochrane risk of bias tool. If possible, funnel plots would be constructed to investigate publication bias. Heterogeneity was calculated via I&lt;sup&gt;2&lt;/sup&gt; statistics. A multidisciplinary guideline panel formulated the recommendation according to Grading of Recommendations Assessment, Development and Evaluation (GRADE). The certainty of evidence was considered either high, moderate, low or very low depending on the extent of risk of bias, inconsistency, imprecision, indirectness, or publication bias. The evidence-to-decision framework was subsequently used to discuss the feasibility and acceptance of the constructed recommendation alongside the impact on resources and equity. The protocol is registered with the Danish Health Authority.

**Findings:**

We included eight RCTs with 419 children and adolescents with idiopathic chronic insomnia. Melatonin led to a moderate increase in total sleep time by 30.33 min (95% confidence interval (CI) 18.96-41.70, 4 studies, I&lt;sup&gt;2&lt;/sup&gt; = 0%) and a moderate reduction in sleep latency by 18.03 min (95% CI -26.61 to -9.44, 3 studies, I&lt;sup&gt;2&lt;/sup&gt; = 0%), both as assessed by sleep diary. No other beneficial effects were found. None of the studies provided information on serious adverse events, yet the number of participants experiencing non-serious adverse events was increased (Relative risk 3.44, 95% CI 1.25-9.42, 4 studies, I&lt;sup&gt;2&lt;/sup&gt; = 0%). Funnel plots were not constructed due to the low number of studies. The certainty of evidence was very low on the quality of sleep and low for daytime functioning. 

**Interpretation:**

Evidence of very low certainty shows that benefits are limited and unwanted events are likely when melatonin is used to treat otherwise healthy children and adolescents with chronic insomnia. Melatonin should never be the first choice of treatment for this particular population, yet carefully monitored short-term use may be considered if sleep hygiene practices and non-pharmacological interventions have proven inadequate, and only if daytime function is compromised. Funding: The Danish Health Authority and the Parker Institute, Bispebjerg and Frederiksberg Hospital supported by the Oak Foundation.
AN  - 37457117
AU  - Edemann-Callesen,
AU  - H.
AU  - Andersen,
AU  - H.
AU  - K.
AU  - Ussing,
AU  - A.
AU  - Virring,
AU  - A.
AU  - Jennum,
AU  - P.
AU  - Debes,
AU  - N.
AU  - M.
AU  - Laursen,
AU  - T.
AU  - Baandrup,
AU  - L.
AU  - Gade,
AU  - C.
AU  - Dettmann,
AU  - J.
AU  - Holm,
AU  - J.
AU  - Krogh,
AU  - C.
AU  - Birkefoss,
AU  - K.
AU  - Tarp,
AU  - S.
AU  - Handel,
AU  - M.
AU  - N.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.eclinm.2023.102048
L1  - internal-pdf://3133542822/Edemann-Callese-2023-Use of melatonin in child.pdf
PY  - 2023
SP  - 102048
T2  - EClinicalMedicine
TI  - Use of melatonin in children and adolescents with idiopathic chronic insomnia: a systematic review, meta-analysis, and clinical recommendation
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37457117
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339205/pdf/main.pdf
VL  - 61
ER  -
TY  - JOUR
AB  - **Background**
Outwardly directed aggressive behaviour in people with intellectual disabilities is a significant issue that may lead to poor quality of life, social exclusion and inpatient psychiatric admissions. Cognitive and behavioural approaches have been developed to manage aggressive behaviour but the effectiveness of these interventions on reducing aggressive behaviour and other outcomes are unclear. This is the third update of this review and adds nine new studies, resulting in a total of 15 studies in this review.

**Objectives**
To evaluate the efficacy of behavioural and cognitive‐behavioural interventions on outwardly directed aggressive behaviour compared to usual care, wait‐list controls or no treatment in people with intellectual disability. We also evaluated enhanced interventions compared to non‐enhanced interventions.

**Search methods**
We used standard, extensive Cochrane search methods. The latest search date was March 2022. We revised the search terms to include positive behaviour support (PBS).

**Selection criteria**
We included randomised and quasi‐randomised trials of children and adults with intellectual disability of any duration, setting and any eligible comparator.

**Data collection and analysis**
We used standard Cochrane methods. Our primary outcomes were change in 1. aggressive behaviour, 2. ability to control anger, and 3. adaptive functioning, and 4. adverse effects. Our secondary outcomes were change in 5. mental state, 6. medication, 7. care needs and 8. quality of life, and 9. frequency of service utilisation and 10. user satisfaction data. We used GRADE to assess certainty of evidence for each outcome.

We expressed treatment effects as mean differences (MD) or odds ratios (OR), with 95% confidence intervals (CI). Where possible, we pooled data using a fixed‐effect model.

**Main results**
This updated version comprises nine new studies giving 15 included studies and 921 participants. The update also adds new interventions including parent training (two studies), mindfulness‐based positive behaviour support (MBPBS) (two studies), reciprocal imitation training (RIT; one study) and dialectical behavioural therapy (DBT; one study). It also adds two new studies on PBS.

Most studies were based in the community (14 studies), and one was in an inpatient forensic service. Eleven studies involved adults only. The remaining studies involved children (one study), children and adolescents (one study), adolescents (one study), and adolescents and adults (one study). One study included boys with fragile X syndrome.

Six studies were conducted in the UK, seven in the USA, one in Canada and one in Germany. Only five studies described sources of funding.

Four studies compared anger management based on cognitive behaviour therapy to a wait‐list or no treatment control group (n = 263); two studies compared PBS with treatment as usual (TAU) (n = 308); two studies compared carer training on mindfulness and PBS with PBS only (n = 128); two studies involving parent training on behavioural approaches compared to wait‐list control or TAU (n = 99); one study of mindfulness to a wait‐list control (n = 34); one study of adapted dialectal behavioural therapy compared to wait‐list control (n = 21); one study of RIT compared to an active control (n = 20) and one study of modified relaxation compared to an active control group (n = 12).

There was moderate‐certainty evidence that anger management may improve severity of aggressive behaviour post‐treatment (MD &minus;3.50, 95% CI &minus;6.21 to &minus;0.79; P = 0.01; 1 study, 158 participants); very low‐certainty evidence that it might improve self‐reported ability to control anger (MD &minus;8.38, 95% CI &minus;14.05 to &minus;2.71; P = 0.004, I2 = 2%; 3 studies, 212 participants), adaptive functioning (MD &minus;21.73, 95% CI &minus;36.44 to &minus;7.02; P = 0.004; 1 study, 28 participants) and psychiatric symptoms (MD &minus;0.48, 95% CI &minus;0.79 to &minus;0.17; P = 0.002; 1 study, 28 participants) post‐treatment; and very low‐certainty evidence that it does not improve quality of life post‐treatment (MD &minus;5.60, 95% CI &minus;18.11 to 6.91; P = 0.38; 1 study, 129 participants) or reduce service utilisation and costs at 10 months (MD 102.99 British pounds, 95% CI &minus;117.16 to 323.14; P = 0.36; 1 study, 133 participants).

There was moderate‐certainty evidence that PBS may reduce aggressive behaviour post‐treatment (MD &minus;7.78, 95% CI &minus;15.23 to &minus;0.32; P = 0.04, I2 = 0%; 2 studies, 275 participants) and low‐certainty evidence that it probably does not reduce aggressive behaviour at 12 months (MD &minus;5.20, 95% CI &minus;13.27 to 2.87; P = 0.21; 1 study, 225 participants). There was low‐certainty evidence that PBS does not improve mental state post‐treatment (OR 1.44, 95% CI 0.83 to 2.49; P = 1.21; 1 study, 214 participants) and very low‐certainty evidence that it might not reduce service utilisation at 12 months (MD &minus;448.00 British pounds, 95% CI &minus;1660.83 to 764.83; P = 0.47; 1 study, 225 participants).

There was very low‐certainty evidence that mindfulness may reduce incidents of physical aggression (MD &minus;2.80, 95% CI &minus;4.37 to &minus;1.23; P &lt; 0.001; 1 study; 34 participants) and low‐certainty evidence that MBPBS may reduce incidents of aggression post‐treatment (MD &minus;10.27, 95% CI &minus;14.86 to &minus;5.67; P &lt; 0.001, I2 = 87%; 2 studies, 128 participants).

Reasons for downgrading the certainty of evidence were risk of bias (particularly selection and performance bias); imprecision (results from single, often small studies, wide CIs, and CIs crossing the null effect); and inconsistency (statistical heterogeneity).

**Authors&#039; conclusions**
There is moderate‐certainty evidence that cognitive‐behavioural approaches such as anger management and PBS may reduce outwardly directed aggressive behaviour in the short term but there is less certainty about the evidence in the medium and long term, particularly in relation to other outcomes such as quality of life. There is some evidence to suggest that combining more than one intervention may have cumulative benefits.

Most studies were small and there is a need for larger, robust randomised controlled trials, particularly for interventions where the certainty of evidence is very low. More trials are needed that focus on children and whether psychological interventions lead to reductions in the use of psychotropic medications.
AU  - Prior,
AU  - D.
AU  - Win,
AU  - S.
AU  - Hassiotis,
AU  - A.
AU  - Hall,
AU  - I.
AU  - Martiello,
AU  - M.
AU  - A.
AU  - Ali,
AU  - A.
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD003406.pub5
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Behavioural and cognitive‐behavioural interventions for outwardly directed aggressive behaviour in people with intellectual disabilities
ER  -
TY  - JOUR
AB  - The last 20 years has seen debate regarding the merits of involving parents in cognitive behavior therapy (CBT) for youth anxiety played out across systematic reviews which have high impact. These reviews examined varying treatment formats in relation to parent involvement, including youth only CBT (Y-CBT), parent only CBT (P-CBT) and family CBT (youth and parent; F-CBT). This is a novel overview of systematic reviews examining evidence for parental involvement in CBT for youth anxiety over the period this was studied. Two independent coders systematically searched for studies in medical and psychological databases using the categories &quot;Review&quot;, &quot;Youth&quot;, &quot;Anxiety&quot;, &quot;Cognitive Behavior Therapy&quot; and &quot;Parent/Family&quot;. Of the 2,189 unique articles identified, there were 25 systematic reviews since 2005 which compared the effects of CBT for youth anxiety with varying parent involvement. Despite systematically studying the same phenomenon, the reviews were heterogeneous in outcome, design, inclusion criteria and often had methodological limitations. Of the 25 reviews, 21 found no difference between formats and 22 reviews were considered inconclusive. Yet while there were typically no statistical differences, consistent patterns in the direction of effects were detected over time. P-CBT was less effective than other formats, suggesting the importance of directly treating anxious youths. Early reviews favored F-CBT over Y-CBT, however, later reviews did not show this trend. We consider the effects of moderators including exposure therapy, long-term outcomes and the child&#039;s age. We consider how to manage heterogeneity in primary studies and reviews to better detect treatment differences where they exist.Trial registration This protocol is registered with the Open Science Framework: osf.io/2u58t. Copyright &copy; 2023. The Author(s).
AU  - Byrne,
AU  - S.
AU  - Cobham,
AU  - V.
AU  - Richardson,
AU  - M.
AU  - Imuta,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-023-00436-5
L1  - internal-pdf://0090667097/Byrne-2023-Do Parents Enhance Cognitive Behavi.pdf
PY  - 2023
T2  - Clinical Child and Family Psychology Review
TI  - Do Parents Enhance Cognitive Behavior Therapy for Youth Anxiety? An Overview of Systematic Reviews Over Time
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37217646
UR  - https://link.springer.com/content/pdf/10.1007/s10567-023-00436-5.pdf
ER  -
TY  - JOUR
AB  - **Background:** 
Suicidal and self-injurious-related behaviors (SSIRBs) are a serious public health challenge in China. However, a comprehensive systematic review of psychosocial interventions for SSIRBs among Chinese adolescents has not been performed. To fill this gap, this systematic review and meta-analysis aimed to examine psychosocial interventions for SSIRBs among Chinese adolescents.

**Methods:** 
Eight international (PubMed, EMBASE, Cochrane Library, ScienceDirect, Clinical Trial, CINAHL, PsycINFO, and Web of Science) and four Chinese (Wanfang, SinoMed, CEPS, and CNKI) databases were searched from inception to 31 January 2023. Data extraction and quality assessment were independently conducted by two groups of researchers. Qualitative synthesis and meta-analysis were both used.

**Results:** 
The initial search yielded 16,872 titles. Of the 649 full texts reviewed, 19 intervention articles focusing on SSIRBs met the inclusion criteria. Thirteen out of the 19 included studies involved cognitive-behavioral therapy (CBT). Seven non-suicidal self-injury (NSSI) studies assessing self-injurious behaviors were included (six short-term studies and three long-term studies). Compared with long-term interventions [-1.30 (95% CI: -1.84, -0.76)], short-term psychosocial interventions had a higher standardized mean difference (SMD) value [1.86 (95% CI: -2.72, -0.99)]. Meta-regression showed an inverse relationship between the treatment response and sample size (slope = 0.068, Z = 2.914, p = 0.004) and proportion of females (slope = 1.096, Z = 5.848, p &lt; 0.001). Subgroup analyses showed that compared with the &quot;less than 1 month&quot; group [-0.494 (-0.783, -0.205)], in the &quot;immediate postintervention&quot; group, the pooled estimate was significantly lower [-2.800 (-4.050, -1.550), p &lt; 0.001].

**Conclusion:** 
Our review systematically summarized the key characteristics and effectiveness of existing psychosocial interventions for SSIRBs among Chinese adolescents. Short-term psychosocial interventions for NSSI were significantly effective in reducing self-injurious behavior scores, especially in the immediate postintervention period. More favorable treatment responses could be observed in both male and small samples.
AN  - WOS:001134240000001
AU  - Lu,
AU  - J.
AU  - J.
AU  - Gao,
AU  - W.
AU  - T.
AU  - Wang,
AU  - Z.
AU  - X.
AU  - Yang,
AU  - N.
AU  - Pang,
AU  - W.
AU  - I.
AU  - P.
AU  - Lok,
AU  - G.
AU  - K.
AU  - I.
AU  - Rao,
AU  - W.
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3389/fpubh.2023.1281696
L1  - internal-pdf://0831816540/Lu-2023-Psychosocial interventions for suicida.pdf
PY  - 2023
SP  - 13
T2  - Frontiers in Public Health
TI  - Psychosocial interventions for suicidal and self-injurious-related behaviors among adolescents: a systematic review and meta-analysis of Chinese practices
UR  - &lt;Go to ISI&gt;://WOS:001134240000001
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/1281696/pubmed-zip/.versions/1/.package-entries/fpubh-11-1281696/fpubh-11-1281696.pdf?sv=2018-03-28&amp;sr=b&amp;sig=h36jxxl4VJvihZjaw5xQD71xiP6ZganPSWt1BGXbCco%3D&amp;se=2024-02-06T12%3A06%3A28Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpubh-11-1281696.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Background**
Pharmacological interventions are frequently used for people with autism spectrum disorder (ASD) to manage behaviours of concern, including irritability, aggression, and self‐injury. Some pharmacological interventions might help treat some behaviours of concern, but can also have adverse effects (AEs).

**Objectives**
To assess the effectiveness and AEs of pharmacological interventions for managing the behaviours of irritability, aggression, and self‐injury in ASD.

**Search methods**
We searched CENTRAL, MEDLINE, Embase, 11 other databases and two trials registers up to June 2022. We also searched reference lists of relevant studies, and contacted study authors, experts and pharmaceutical companies.

**Selection criteria**
We included randomised controlled trials of participants of any age with a clinical diagnosis of ASD, that compared any pharmacological intervention to an alternative drug, standard care, placebo, or wait‐list control.

**Data collection and analysis**
We used standard Cochrane methods. Primary outcomes were behaviours of concern in ASD, (irritability, aggression and self‐injury); and AEs. Secondary outcomes were quality of life, and tolerability and acceptability. Two review authors independently assessed each study for risk of bias, and used GRADE to judge the certainty of the evidence for each outcome.

**Main results**
We included 131 studies involving 7014 participants in this review. We identified 26 studies as awaiting classification and 25 as ongoing. Most studies involved children (53 studies involved only children under 13 years), children and adolescents (37 studies), adolescents only (2 studies) children and adults (16 studies), or adults only (23 studies). All included studies compared a pharmacological intervention to a placebo or to another pharmacological intervention.

Atypical antipsychotics versus placebo

At short‐term follow&minus;up (up to 6 months), atypical antipsychotics probably reduce irritability compared to placebo (standardised mean difference (SMD) &minus;0.90, 95% confidence interval (CI) &minus;1.25 to &minus;0.55, 12 studies, 973 participants; moderate‐certainty evidence), which may indicate a large effect. However, there was no clear evidence of a difference in aggression between groups (SMD &minus;0.44, 95% CI &minus;0.89 to 0.01; 1 study, 77 participants; very low‐certainty evidence). Atypical antipsychotics may also reduce self‐injury (SMD &minus;1.43, 95% CI &minus;2.24 to &minus;0.61; 1 study, 30 participants; low‐certainty evidence), possibly indicating a large effect.

There may be higher rates of neurological AEs (dizziness, fatigue, sedation, somnolence, and tremor) in the intervention group (low‐certainty evidence), but there was no clear evidence of an effect on other neurological AEs. Increased appetite may be higher in the intervention group (low‐certainty evidence), but we found no clear evidence of an effect on other metabolic AEs. There was no clear evidence of differences between groups in musculoskeletal or psychological AEs.

Neurohormones versus placebo

At short‐term follow‐up, neurohormones may have minimal to no clear effect on irritability when compared to placebo (SMD &minus;0.18, 95% CI &minus;0.37 to &minus;0.00; 8 studies; 466 participants; very low‐certainty evidence), although the evidence is very uncertain. No data were reported for aggression or self ‐injury.

Neurohormones may reduce the risk of headaches slightly in the intervention group, although the evidence is very uncertain. There was no clear evidence of an effect of neurohormones on any other neurological AEs, nor on any psychological, metabolic, or musculoskeletal AEs (low‐ and very low‐certainty evidence).

Attention‐deficit hyperactivity disorder (ADHD)‐related medications versus placebo

At short‐term follow‐up, ADHD‐related medications may reduce irritability slightly (SMD &minus;0.20, 95% CI &minus;0.40 to &minus;0.01; 10 studies, 400 participants; low‐certainty evidence), which may indicate a small effect. However, there was no clear evidence that ADHD‐related medications have an effect on self‐injury (SMD &minus;0.62, 95% CI &minus;1.63 to 0.39; 1 study, 16 participants; very low‐certainty evidence). No data were reported for aggression.

Rates of neurological AEs (drowsiness, emotional AEs, fatigue, headache, insomnia, and irritability), metabolic AEs (decreased appetite) and psychological AEs (depression) may be higher in the intervention group, although the evidence is very uncertain (very low‐certainty evidence). There was no evidence of a difference between groups for any other metabolic, neurological, or psychological AEs (very low‐certainty evidence). No data were reported for musculoskeletal AEs.

Antidepressants versus placebo

At short‐term follow‐up, there was no clear evidence that antidepressants have an effect on irritability (SMD &minus;0.06, 95% CI &minus;0.30 to 0.18; 3 studies, 267 participants; low‐certainty evidence). No data for aggression or self‐injury were reported or could be included in the analysis.

Rates of metabolic AEs (decreased energy) may be higher in participants receiving antidepressants (very low‐certainty evidence), although no other metabolic AEs showed clear evidence of a difference. Rates of neurological AEs (decreased attention) and psychological AEs (impulsive behaviour and stereotypy) may also be higher in the intervention group (very low‐certainty evidence) although the evidence is very uncertain. There was no clear evidence of any difference in the other metabolic, neurological, or psychological AEs (very low‐certainty evidence), nor between groups in musculoskeletal AEs (very low‐certainty evidence).

Risk of bias

We rated most of the studies across the four comparisons at unclear overall risk of bias due to having multiple domains rated as unclear, very few rated as low across all domains, and most having at least one domain rated as high risk of bias.

**Authors&#039; conclusions**
Evidence suggests that atypical antipsychotics probably reduce irritability, ADHD‐related medications may reduce irritability slightly, and neurohormones may have little to no effect on irritability in the short term in people with ASD. There was some evidence that atypical antipsychotics may reduce self‐injury in the short term, although the evidence is uncertain. There was no clear evidence that antidepressants had an effect on irritability. There was also little to no difference in aggression between atypical antipsychotics and placebo, or self‐injury between ADHD‐related medications and placebo. However, there was some evidence that atypical antipsychotics may result in a large reduction in self‐injury, although the evidence is uncertain. No data were reported (or could be used) for self‐injury or aggression for neurohormones versus placebo. Studies reported a wide range of potential AEs. Atypical antipsychotics and ADHD‐related medications in particular were associated with an increased risk of metabolic and neurological AEs, although the evidence is uncertain for atypical antipsychotics and very uncertain for ADHD‐related medications. The other drug classes had minimal or no associated AEs.
AU  - Iffland,
AU  - M.
AU  - Livingstone,
AU  - N.
AU  - Jorgensen,
AU  - M.
AU  - Hazell,
AU  - P.
AU  - Gillies,
AU  - D.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD011769.pub2
L1  - internal-pdf://3821345598/Iffland_et_al-2023-Cochrane_Database_of_System.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Pharmacological intervention for irritability, aggression, and self-injury in autism spectrum disorder (
ER  -
TY  - JOUR
AB  - BACKGROUND: Over the past 16 years, we have developed a &#039;Meta-analytic Research Domain&#039; (MARD) of all randomized trials of psychological treatments of depression. A MARD is a living systematic review of a research field, that cannot be otherwise covered by one (network) meta-analysis and includes multiple PICOs. In this paper we give an overview of the findings of this MARD.

METHODS: A narrative review of the results of the 118 meta-analyses on psychotherapies for depression that were published within our MARD.

RESULTS: Most research has been conducted on cognitive-behavioral therapy (CBT), but several other psychotherapies are also effective, with few differences between therapies. They can be effectively delivered in individual, group, telephone and guided self-help format and are effective in many different target groups and across different age groups, although the effects are significantly smaller in children and adolescents. Psychotherapies have comparable effects as pharmacotherapy at the short term but are probably more effective at the longer term. Combined treatment is more effective than either psychotherapy or pharmacotherapy alone at the short, but also at the longer term.

LIMITATIONS: We did not summarize all published meta-analyses (protocols, methodological studies) and have not compared our results to those found in other meta-analyses on comparable subjects.

CONCLUSION: Psychotherapies can contribute considerably to a reduction of the disease burden of depression. MARDs are an important next step in the aggregation of knowledge from randomized controlled trials in psychological treatments of depression as well as in other healthcare sectors. Copyright &copy; 2023 The Author(s). Published by Elsevier B.V. All rights reserved.
AU  - Cuijpers,
AU  - P.
AU  - Miguel,
AU  - C.
AU  - Harrer,
AU  - M.
AU  - Plessen,
AU  - C.
AU  - Y.
AU  - Ciharova,
AU  - M.
AU  - Papola,
AU  - D.
AU  - Ebert,
AU  - D.
AU  - Karyotaki,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2023.05.011
L1  - internal-pdf://4045703036/1-s2.0-S0165032723006389-main.cleaned.pdf
PY  - 2023
SP  - 141-151
T2  - Journal of Affective Disorders
TI  - Psychological treatment of depression: A systematic overview of a &#039;Meta-Analytic Research Domain&#039;
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37178828
UR  - https://www.sciencedirect.com/science/article/pii/S0165032723006389?via%3Dihub
VL  - 335
ER  -
TY  - JOUR
AB  - **Background:** 
Autism spectrum disorder (ASD) is a severe public health concern, and most of the children with ASD experience a substantial delay in FMS. This study aimed to investigate the effectiveness of exercise interventions in improving FMS in children with ASD, and provide evidence to support the scientific use of exercise interventions in practice. 

**Methods:** 
We searched seven online databases (PubMed, Scopus, Web of Science, Embase, EBSCO, Clinical Trials, and The Cochrane Library) from inception to May 20, 2022. We included randomized control trials of exercise interventions for FMS in children with ASD. The methodological quality of the included studies was assessed using the Physiotherapy Evidence Database Scale. Stata 14.0 software was used for meta-analysis, forest plotting, subgroup analysis, heterogeneity analysis, and meta-regression. 

**Results:** 
Thirteen studies underwent systematic review (541 participants), of which 10 underwent meta-analysis (297 participants). Overall, exercise interventions significantly improved overall FMS in children with ASD. Regarding the three categories of FMS, exercise interventions significantly improved LMS (SMD = 1.07; 95% CI 0.73 to 1.41, p &lt; 0.001), OCS (SMD = 0.79; 95% CI 0.32 to 1.26, p = 0.001), and SS (SMD = 0.72; 95% CI 0.45 to 0.98, p &lt; 0.0001). 

**Conclusion:** 
exercise interventions can effectively improve the FMS of children with ASD. The effects on LMS are considered as large effect sizes, while the effects on OCS and SS are considered as moderate effect sizes. These findings can inform clinical practice. Systematic review registration: https://inplasy.com/inplasy-2022-12-0013/.
AN  - 37377477
AU  - Ji,
AU  - Y.
AU  - Q.
AU  - Tian,
AU  - H.
AU  - Zheng,
AU  - Z.
AU  - Y.
AU  - Ye,
AU  - Z.
AU  - Y.
AU  - Ye,
AU  - Q.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyt.2023.1132074
L1  - internal-pdf://1954142217/pdf.cleaned (4).pdf
PY  - 2023
SP  - 1132074
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Effectiveness of exercise intervention on improving fundamental motor skills in children with autism spectrum disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37377477
VL  - 14
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Children represent nearly 40% of forcibly displaced populations and are subject to stressors that affect well-being. Little is known about the effects of interventions to enhance psychological resilience in these children, outside clinical settings. 

METHODS: 
We conducted a systematic review, following Cochrane methods. Eligible studies tested resilience-enhancing interventions outside clinical settings in forcibly displaced children/adolescents. We included longitudinal quantitative studies with comparator conditions irrespective of geographical scope or language. We searched articles published between January 2010 and April 2020 in PubMed, Embase, Cochrane Library, Web of Science, PsycINFO and the WHO&#039;s Global Index Medicus. To standardise effect sizes across the different reported outcomes, we transformed reported mean differences to standardised mean differences using Hedge&#039;s g statistic with associated 95% CI. We pooled data for meta-analysis where appropriate. We used Cochrane tools to assess study risk of bias and used Grading of Recommendations Assessment, Development and Evaluation to determine evidence quality for meta-analysed outcomes.

RESULTS: 
Searches yielded 4829 results. Twenty-three studies met inclusion criteria. Studies reported 18 outcomes measured by 48 different scales; only 1 study explicitly measured resilience. Eight studies were randomised controlled trials; the rest were non-randomised pre-post studies. Interventions were diverse and typically implemented in group settings. Studies reported significant improvement in outcomes pertinent to behavioural problems, coping mechanisms and general well-being but not to caregiver support or psychiatric symptoms. In meta-analysis, resilience was improved (g&lt;sub&gt;av&lt;/sub&gt;=0.194, 95% CI 0.018 to 0.369), but anxiety symptoms and quality of life were not (g&lt;sub&gt;av&lt;/sub&gt;=-0.326, 95% CI -0.782 to 0.131 and g&lt;sub&gt;av&lt;/sub&gt;=0.325, 95% CI -0.027 to 0.678, respectively). Risk of bias varied. Quality of evidence for most graded outcomes was very low. 

CONCLUSIONS: 
The multiplicity of study designs, intervention types, outcomes and measures incumbered quantifying intervention effectiveness. Future resilience research in this population should use rigorous methods and follow reporting guidelines. Prospero registration number: Crd42020177069.
AN  - 36731918
AU  - Thabet,
AU  - A.
AU  - Ghandi,
AU  - S.
AU  - Barker,
AU  - E.
AU  - K.
AU  - Rutherford,
AU  - G.
AU  - Malekinejad,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1136/bmjgh-2021-007320
L1  - internal-pdf://1051987929/Thabet-2023-Interventions to enhance psycholog.pdf
PY  - 2023
T2  - BMJ Global Health
TI  - Interventions to enhance psychological resilience in forcibly displaced children: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36731918
UR  - https://gh.bmj.com/content/bmjgh/8/2/e007320.full.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **Background and Aim**
Crocus sativus also known as saffron, is one of the most popular traditional plants. This study aims to evaluate the efficacy and safety of saffron extracts in ADHD.

**Method**
This study includes clinical trial studies that assessed the efficacy and/or safety of saffron in ADHD patients. Non-English papers, review articles, commentaries, letters, observational studies, thesis, animal studies, in-vitro studies, and conference abstracts were not included. The risk of bias in randomized studies was evaluated based on the Cochrane RoB.2, and risk of bias in pre-post intervention studies was assessed using the ROBINS-I tool.

**Results**
Four studies met our inclusion criteria with a total of 118 patients. The results manifested an efficient role of saffron as either an adjuvant therapy to MPH or a single therapy against ADHD, without significant safety issues.Discussion: Saffron demonstrates promise in improving ADHD symptoms, with an acceptable safety profile. Future well-designed multicentral studies are suggested.
AN  - WOS:001089264800001
AU  - Seyedi-Sahebari,
AU  - S.
AU  - Farhang,
AU  - S.
AU  - Araj-Khodaei,
AU  - M.
AU  - Akhondzadeh,
AU  - S.
AU  - Naseri,
AU  - A.
AU  - Sanaie,
AU  - S.
AU  - Frounchi,
AU  - N.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1177/10870547231203176
L1  - internal-pdf://1382162730/seyedi-sahebari-et-al-2023-the-effects-of-croc.pdf
PY  - 2023
SP  - 11
T2  - Journal of Attention Disorders
TI  - The Effects of <i>Crocus sativus</i> (Saffron) on ADHD: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001089264800001
ER  -
TY  - JOUR
AB  - **Background**
Family-systems interventions have been proposed as one way of supporting families of people with an intellectual disability (ID) or who are autistic. This systematic review aimed to summarise what family-systems interventions have been studied with this population, what evidence there is for their effectiveness and families&#039; experiences of the interventions. 

**Methods**
The review was preregistered on PROSPERO (CRD42022297516). We searched five electronic databases, identified 6908 records and screened 72 full texts. Study quality was evaluated using the Mixed Methods Appraisal Tool, and a narrative synthesis was used.

**Results**
We identified 13 eligible articles with 292 participating families. Most studies reported positive effects of the interventions on wellbeing and family relationships, and families reported positive experiences. However, research quality was poor and there are no any sufficiently powered randomised controlled trials demonstrating family-systems interventions&#039; effectiveness for this population. 

**Conclusions**
There is a need for higher-quality research to establish whether family-systems interventions are beneficial for families of people who have an ID or who are autistic.
AN  - WOS:001039344800001
AU  - Sutherland,
AU  - D.
AU  - Flynn,
AU  - S.
AU  - Kurzeja,
AU  - O.
AU  - Griffin,
AU  - J.
AU  - Hastings,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1111/jir.13068
L1  - internal-pdf://3636998150/Sutherland-2023-Family-systems interventions f.pdf
PY  - 2023
SP  - 26
T2  - Journal of Intellectual Disability Research
TI  - Family-systems interventions for families of people with an intellectual disability or who are autistic: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:001039344800001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jir.13068?download=true
ER  -
TY  - JOUR
AB  - **Background** 
Dramatherapy, a creative form of psychotherapy, may be a useful treatment for child and adolescent mental health. As there is a growing evidence base, this systematic review sought to identify, describe and evaluate dramatherapy with children and adolescents who were experiencing emotional distress (anxiety, depression and trauma) in order to inform future research in this area. 

**Methods** 
Seven databases (PsychInfo, PubMed, Scopus, Web of Science, CINAHL, EMBASE and Cochrane) were searched for peer-reviewed articles exploring dramatherapy as a treatment for child and adolescent emotional distress. Hand searches of relevant journals were also conducted. Two reviewers coded articles for eligibility and independently appraised papers using the Joanna Briggs Institute Critical Appraisal Tools. Details relating to intervention and participant characteristics were extracted and, where data were available, effect sizes on measures relating to emotional distress were calculated. 

**Results** 
Fifteen papers were included. Studies showed that dramatherapy was often delivered in schools (46%) and clinical settings (20%) and was more frequently delivered to adolescents (53%) (&gt;11 years) than children (26%) (8-11 years). Dramatherapy was used as a treatment for diagnostically heterogeneous groups (40%), for emotional and behavioural difficulties (33%) and following a shared, traumatic, experience (20%). Seven papers reported relevant quantitative data however, just three of these studies were controlled and none were blinded. Pre-to-post intervention effect sizes ranged from d = 0.17 to d &gt; 2 yet samples were small and participant response to treatment was not always consistent. The largest effects were seen in dramatherapy employed following trauma and in clinical settings. Medium to large effects were also seen in early intervention school-based dramatherapy. 

**Conclusion** 
Despite promising results with regards to the treatment of child and adolescent emotional distress, the evidence base for dramatherapy is small and methodologically flawed. Larger, methodologically robust trials should test the efficacy of dramatherapy in future research. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-52450-001
AU  - Keiller,
AU  - E.
AU  - Tjasink,
AU  - M.
AU  - Bourne,
AU  - J.
AU  - Ougrin,
AU  - D.
AU  - Carr,
AU  - C.
AU  - E.
AU  - Lau,
AU  - J.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/jcv2.12145
L1  - internal-pdf://3539056068/Keiller-2023-A systematic review of dramathera.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - JCPP Advances
TI  - A systematic review of dramatherapy interventions used to alleviate emotional distress and support the well-being of children and young people aged 8-18 years old
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-52450-001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcv2.12145?download=true
ER  -
TY  - JOUR
AB  - Self-disclosure, referring to the ability to communicate and share intimate personal feelings, has strong face validity for many young people as a way of improving anxiety and depression outcomes. The current review aimed to generate the first comprehensive evidence synthesis of self-disclosure interventions involving young people aged 14-24 years who are either disclosers or recipients of personal information about living with anxiety and/or depression. 

A systematic review of quantitative and qualitative data was combined with new insights from an adolescents and young adults lived-experience panel (n = 7) with the intention to combine rigorous systematic review methods and experiential knowledge. 

Six studies of variable quality were included in this review, five were quantitative and one was qualitative. Findings suggest that self-disclosure may be effective at reducing symptoms for adolescents and young adults with established depression; effects were not apparent when delivered as early prevention. No evidence for impacts on anxiety was found. The potential for negative effects like bullying or harassment was identified. Findings were limited by a small number of studies; low representation of peer-reviewed studies from low-or middle-income countries; and varied interventions in terms of format, participants&#039; context, and nature of delivery. 

Self-disclosure may be of value in the context of interventions intended explicitly to reduce depression for those already showing symptoms. Delivery by non-specialists (such as peers and teachers) in addition to mental health professionals can help build capacity in community health systems. Self-disclosure may also be helpful at reducing stigma and stimulating help-seeking at earlier stages of mental health problems.
AN  - 36738384
AU  - Gonsalves,
AU  - P.
AU  - P.
AU  - Nair,
AU  - R.
AU  - Roy,
AU  - M.
AU  - Pal,
AU  - S.
AU  - Michelson,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10488-023-01253-2
L1  - internal-pdf://0928561974/Gonsalves-2023-A Systematic Review and Lived E.pdf
PY  - 2023
SP  - 04
T2  - Administration &amp; Policy in Mental Health
TI  - A Systematic Review and Lived Experience Synthesis of Self-disclosure as an Active Ingredient in Interventions for Adolescents and Young Adults with Anxiety and Depression
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36738384
UR  - https://link.springer.com/content/pdf/10.1007/s10488-023-01253-2.pdf
VL  - 04
ER  -
TY  - JOUR
AB  - BACKGROUND: Exergames are promising exercise tools for improving health. To the best of our knowledge, no systematic review has compared the effects of commercial exergames and conventional exercises on improving executive functions (EFs) in children and adolescents.

OBJECTIVE: This study aimed to investigate the effects of commercial exergames and conventional exercises on improving EFs in children and adolescents.METHODS: Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, 5 randomized controlled trial (RCT) databases (PubMed, Web of Science, Scopus, PsycINFO, and SPORTDiscus) were searched from their inception to July 7, 2022, to identify relevant RCTs. The Cochrane Collaboration tool was used to evaluate the risk of bias for each study. GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) was used to evaluate the overall quality of evidence.

RESULTS: In total, 8 RCTs including 435 children and adolescents were included in the analysis. Commercial exergames had no significant benefit on overall EFs compared to conventional exercises (Hedges g=1.464, 95% CI -0.352 to 3.280; P=.06). For core EFs, there was no evidence to suggest that commercial exergames are more beneficial for improving cognitive flexibility (g=0.906, 95% CI -0.274 to 2.086; P=.13), inhibitory control (g=1.323, 95% CI -0.398 to 3.044; P=.13), or working memory (g=2.420, 95% CI -1.199 to 6.038; P=.19) than conventional exercises. We rated the evidence for overall EFs, cognitive flexibility, inhibitory control, and working memory as being of very low quality due to inconsistency (large heterogeneity) and imprecision (low number of people). Additionally, no effects of the intervention were observed in the acute and chronic groups.

CONCLUSIONS: We do not have strong evidence to support the benefit of commercial exergaming on EFs because we did not observe a Hedges g close to 0 with tight CIs. Further research is needed to confirm this hypothesis.

TRIAL REGISTRATION: PROSPERO CRD42022324111; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=324111.
AD  - Wu, Jinlong. College of Physical Education, Southwest University, Chongqing, China.Xu, Zhuang. College of Physical Education, Southwest University, Chongqing, China.Liu, Haowei. College of Physical Education, Southwest University, Chongqing, China.Chen, Xiaoke. Department of Physical Education, Tsinghua University, Beijing, China.Huang, Li. College of Physical Education, Southwest University, Chongqing, China.Shi, Qiuqiong. Laboratory for Artificial Intelligence in Design, Hong Kong, China.Weng, Linman. Faculty of Psychology, Southwest University, Chongqing, China.Ji, Yemeng. College of Physical Education, Southwest University, Chongqing, China.Zeng, Hao. College of Physical Education, Nanchang University, Nanchang, China.Peng, Li. College of Physical Education, Southwest University, Chongqing, China.
AN  - 37856191
AU  - Wu,
AU  - J.
AU  - Xu,
AU  - Z.
AU  - Liu,
AU  - H.
AU  - Chen,
AU  - X.
AU  - Huang,
AU  - L.
AU  - Shi,
AU  - Q.
AU  - Weng,
AU  - L.
AU  - Ji,
AU  - Y.
AU  - Zeng,
AU  - H.
AU  - Peng,
AU  - L.
DA  - Oct 19
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/42697
DP  - Ovid Technologies
J2  - JMIR Serious Games
L1  - internal-pdf://2982501999/PDF.cleaned (5).pdf
LA  - English
N1  - Wu, JinlongXu, ZhuangLiu, HaoweiChen, XiaokeHuang, LiShi, QiuqiongWeng, LinmanJi, YemengZeng, HaoPeng, Li
PY  - 2023
SP  - e42697
T2  - JMIR Serious Games
TI  - Effects of Commercial Exergames and Conventional Exercises on Improving Executive Functions in Children and Adolescents: Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37856191
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37856191&amp;id=doi:10.2196%2F42697&amp;issn=2291-9279&amp;isbn=&amp;volume=11&amp;issue=&amp;spage=e42697&amp;pages=e42697&amp;date=2023&amp;title=JMIR+Serious+Games&amp;atitle=Effects+of+Commercial+Exergames+and+Conventional+Exercises+on+Improving+Executive+Functions+in+Children+and+Adolescents%3A+Meta-Analysis+of+Randomized+Controlled+Trials.&amp;aulast=Wu&amp;pid=%3Cauthor%3EWu+J%3C%2Fauthor%3E%3CAN%3E37856191%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 11
ER  -
TY  - JOUR
AB  - **Aim.** This study aimed to investigate whether arts-based interventions are effective in reducing the pain and anxiety of children during venipuncture.

**Material and methods.** Our search involved 9 databases, including Cumulative Index to Nursing and Allied Health Literature, ScienceDirect, Scopus, MEDLINE, EMBASE via PsycINFO, LILACS, ERIC, Web of Science, Google Scholar, and Dissertation Abstracts International until 31 December 2021. Clinical trials in humans published in English randomized or non-randomized were the main criteria for eligibility.

**Results.** We included five RCTs in our review and all were included in our meta-analysis. Quantitative analysis of different clinical parameters was described. In the art-based intervention compared with the control group in terms of reduction in pain mean deviation was -0.68; 95% confidence interval: -1.14, -0.22), whereas the art-based intervention compared with the control group in terms of anxiety reduction mean deviation: -0.78; 95% confidence interval: -1.47, -0.09) during venipuncture procedures.

**Conclusions.** In this study, art-based interventions were found to be effective for children undergoing venipuncture. However, most studies have a high risk of bias and are of low quality, so the results cannot be generalized.
AN  - WOS:001111356400001
AU  - Suleman,
AU  - S.
AU  - Halek,
AU  - M.
AU  - Enskaer,
AU  - K.
AU  - Atrushi,
AU  - A.
AU  - Nilsson,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.2478/pielxxiw-2023-0031
L1  - internal-pdf://3596306541/Suleman-2023-A systematic review and meta-anal.pdf
PY  - 2023
SP  - 8
T2  - Pielegniarstwo Xxi Wieku-Nursing in the 21 Century
TI  - A systematic review and meta-analysis of the effect of art-based psychological distraction on school-aged children&#039;s pain and anxiety during painful procedures
UR  - &lt;Go to ISI&gt;://WOS:001111356400001
UR  - https://intapi.sciendo.com/pdf/10.2478/pielxxiw-2023-0031
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Pokemon GO, an augmented reality game with widespread popularity, can potentially influence players&#039; physical activity (PA) levels and psychosocial well-being. 

**OBJECTIVE**
This review aims to systematically examine the scientific evidence regarding the impact of Pokemon GO on PA and psychosocial well-being in children and adolescents. 

**METHODS**
Using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and the GRADE (Grading of Recommendations, Assessment, Development, and Evaluations) framework, we conducted keyword and reference searches in the PubMed, CINAHL, Web of Science, and Scopus databases. We performed title and abstract screening, full-text review, evidence synthesis, and identified research gaps. 

**RESULTS**
Our review included 10 studies that explored the effect of Pokemon GO on PA or psychosocial well-being among children and adolescents. These studies used diverse designs across multiple countries and regions. Pokemon GO use measures encompassed frequency, experience, adherence, and motivation. PA assessment methods ranged from self-reported questionnaires to technology-based evaluations and qualitative approaches. Psychosocial well-being measures included emotional intelligence, personal well-being, self-control, emotionality, and sociability. In general, the estimated impact of Pokemon GO on PA was positive, with gaming elements and engagement correlating with increased PA levels. However, the effect on psychosocial well-being presented mixed results, with positive associations for sociability but a complex relationship involving well-being and internet gaming disorder. The limitations of these studies comprised the absence of randomized controlled trials, heterogeneity in study designs and outcome measures, and potential confounding bias. 

**CONCLUSIONS**
Overall, Pokemon GO tends to positively affect PA levels, while the impact on psychosocial well-being remains complex and requires further investigation. Future research should investigate the mechanisms connecting Pokemon GO use with PA and psychosocial well-being and the potential risks of excessive gameplay. These findings can help inform public health interventions to harness gaming technologies for promoting PA and enhancing well-being among the younger generation. TRIAL REGISTRATION: PROSPERO International Prospective Register of Systematic Reviews CRD42023412032; https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=412032.
AN  - 37955949
AU  - Liang,
AU  - H.
AU  - Wang,
AU  - X.
AU  - An,
AU  - R.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.2196/49019
L1  - internal-pdf://0976690561/PDF.cleaned (7).pdf
PY  - 2023
SP  - e49019
T2  - Journal of Medical Internet Research
TI  - Influence of Pokemon GO on Physical Activity and Psychosocial Well-Being in Children and Adolescents: Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37955949
VL  - 25
ER  -
TY  - JOUR
AB  - Supervised practice pairs behavioral rehearsal (i.e., the practice of skills) with constructive and supportive feedback so that learners can enact new skills accurately and develop the motivation to consistently apply these skills. The current review study takes stock of the literature on supervised practice through second-order meta-analysis, a rigorous quantitative method used to aggregate overall effects from previous meta-analyses. Results from five meta-analyses revealed a significant overall effect of supervised practice compared to unsupervised practice (SMD = 0.22). Youth outcome type significantly moderated the effects of supervised practice, with internalizing behavior yielding the largest effect. Findings suggest that providing opportunities for supervised practice has the potential to significantly improve the effectiveness of a range of skills-based interventions. Implications for supervised practice are discussed, including as an adjunct to cognitive behavioral interventions and a valuable role for volunteers and other paraprofessionals in their delivery of research supported care. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AU  - Christensen,
AU  - K.
AU  - M.
AU  - Assink,
AU  - M.
AU  - van
AU  - Dam,
AU  - L.
AU  - Stams,
AU  - G.-J.
AU  - Poon,
AU  - C.
AU  - Y.
AU  - S.
AU  - Astesano,
AU  - J.
AU  - Rhodes,
AU  - J.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10560-023-00921-4
L1  - internal-pdf://3827005170/Christensen-2023-Youth interventions with and.pdf
PY  - 2023
SP  - No-Specified
T2  - Child &amp; Adolescent Social Work Journal
TI  - Youth interventions with and without supervised practice: A second-order meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=psyc21&amp;NEWS=N&amp;AN=2023-60939-001
UR  - https://link.springer.com/article/10.1007/s10560-023-00921-4
UR  - https://link.springer.com/content/pdf/10.1007/s10560-023-00921-4.pdf
ER  -
TY  - JOUR
AB  - Parenting programs are the most common intervention for preventing the lethal form of child maltreatment, abusive head trauma (AHT). However, certain results of the effects of these programs have not yet been compared across studies. A systematic review with meta-analysis is warranted to quantitively synthesize the available evidence to identify effective elements and strategies of the programs for preventing AHT. This review aims to estimate AHT preventive parenting programs&#039; pooled effect on the reduction of AHT incidence, the improvement of parental knowledge, and the increased use of safe strategies in response to infants&#039; inconsolable crying. 

Studies published in English and Mandarin were searched and retained if they were randomized control trials (RCTs) or with a quasi-experimental design, included an AHT preventive parenting program, and provided data that quantified targeted outcomes. 

Eighteen studies were included in this review. AHT preventive parenting programs had a pooled effect on improving parents&#039; knowledge and increasing the use of safe coping strategies in response to inconsolable crying but not on the incidence of AHT and parents&#039; emotional self-regulation. Subgroup analyses showed that the intervention effects were mostly present across study designs or measurements and emerged in the reduction of AHT incidence compared with historical controls. 

The findings suggest that AHT preventive parenting programs enhance parenting knowledge and skills to provide safe care for infants. Further efforts to evaluate AHT parenting programs on the reduction of AHT incidence are necessary for decision-making on allocating and disseminating interventions.
AN  - 36762510
AU  - Chang,
AU  - H.
AU  - Y.
AU  - Chang,
AU  - Y.
AU  - C.
AU  - Chang,
AU  - Y.
AU  - T.
AU  - Chen,
AU  - Y.
AU  - W.
AU  - Wu,
AU  - P.
AU  - Y.
AU  - Feng,
AU  - J.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/15248380231151690
L1  - internal-pdf://3879514795/15248380231151690.cleaned.pdf
PY  - 2023
SP  - 15248380231151690
T2  - Trauma Violence &amp; Abuse
TI  - The Effectiveness of Parenting Programs in Preventing Abusive Head Trauma: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36762510
ER  -
TY  - JOUR
AB  - **Background:** 
Tic disorders (TD) are a kind of neuropsychiatric disease that frequently occur among preschool and school-age children, mainly characterized by motor tics or sometimes accompanied by vocal tics, and its pathogenesis is still unclear. The clinical manifestations are mainly characterized by chronic multiple movements, rapid muscle twitching, involuntary occurrence, and language disorder. Acupuncture, tuina, traditional Chinese medicine, and other methods are commonly used in clinical treatments, which have unique therapeutic advantages but have not been recognized and accepted by the international community. This study conducted a quality evaluation and meta-analysis of the currently published randomized controlled trials (RCTs) of acupuncture for TD in children in order to provide reliable evidence-based medical evidence for acupuncture for TD.

**Methods:** 
All the randomized controlled trials (RCTs) using the intervention methods acupuncture + traditional Chinese medical herbs, acupuncture + tuina, and acupuncture, and the control group using Western medicine were included in the analysis. The main outcomes were obtained by using the Yale Global Tic Severity Scale (YGTSS), the Traditional Chinese medicine (TCM) syndrome score scale, and clinical treatment efficiency. Secondary outcomes included adverse events. The risk of bias in the included studies was assessed according to the tool recommended by Cochrane 5.3. The risk of bias assessment chart, risk of bias summary chart, and evidence chart in this study will be produced using R and Stata software.

**Results:** 
There were 39 studies that met the inclusion criteria, including 3,038 patients. In terms of YGTSS, the TCM syndrome score scale changes and shows a clinically effective rate, and we found that acupuncture combined with Chinese medicine is the best treatment.

**Conclusion:** 
Acupuncture + traditional Chinese medical herbs may be the best therapy to improve TD in children. At the same time, compared with Western medicine commonly used in clinical practice, acupuncture and acupuncture combined with tuina therapy have better effects on improving TD in children. Copyright &copy; 2023 Pu, Liu, Wang, Zhang, Zhang, Ran, Sheng, Yi, Ye, Li, Wang, Chi and Luo.
AU  - Pu,
AU  - T.
AU  - Liu,
AU  - Y.
AU  - Wang,
AU  - J.
AU  - Zhang,
AU  - J.
AU  - Zhang,
AU  - J.
AU  - Ran,
AU  - Z.
AU  - Sheng,
AU  - Q.
AU  - Yi,
AU  - Z.
AU  - Ye,
AU  - J.
AU  - Li,
AU  - Y.
AU  - Wang,
AU  - X.
AU  - Chi,
AU  - H.
AU  - Luo,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fnins.2023.1156308
L1  - internal-pdf://2164752238/Pu-2023-Acupuncture and other traditional Chin.pdf
PY  - 2023
SP  - 1156308
T2  - Frontiers in Neuroscience
TI  - Acupuncture and other traditional Chinese medicine therapies in the treatment of children&#039;s tic syndrome: A network meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=pmnm&amp;NEWS=N&amp;AN=37144087
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153442/pdf/fnins-17-1156308.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - **Background** 
Research on the use of digital technologies for delivering behavioral interventions has shown mixed evidence on their efficacy for improving both autistic symptoms and co-occurring psychiatric disorders. Little knowledge exists on the specific use or efficacy of using social media in interventions aimed at autistic individuals.Objective To review and describe the current existing evidence-based research on the use of social media in interventions aimed at autistic individuals.

**Methods** 
A search was conducted across 8 databases (PubMed; EMBASE; Cochrane Library; PsycInfo; ERIC; Education Source; Web of Science; and IEEE Xplore). We included primary studies and reviews that dealt with autism spectrum disorder (ASD); described interventions that use social media; and reported results from the intervention. The quality of the evidence of the included primary studies was graded according to the GRADE criteria, and the risk of bias in systematic reviews was assessed by drawing on the AMSTAR guidelines. Results were synthesized and sorted by quality of evidence.

**Results**
A total of nine articles were included in this review: eight primary studies (five non-randomized interventions and three randomized interventions) and one systematic review. The total number of participants with an ASD-diagnosis in the included studies was 164 (aged 5 to 22 years old). Studies weighted as being of moderate quality of evidence have reported significant positive effects in the groups that received the social media interventions: increased social engagement and participation in life situations; increased physical activity level; increased improvement on occupational performance, specified goals, and behavioral problems; and decreased plaque scores coupled with parent reports of intervention success. None of the studies have reported any negative effects linked to social media interventions.

**Conclusion** 
There is very little evidence of good quality on the use of social media in interventions aimed at autistic individuals. While there is a need for more high-quality studies, all the included studies, with one exception found positive results of the interventions. These findings are encouraging, suggesting that social media-based interventions may in fact be useful for supporting behavioral changes in autistic individuals.
AN  - WOS:000952248800001
AU  - Gabarron,
AU  - E.
AU  - Skafle,
AU  - I.
AU  - Nordahl-Hansen,
AU  - A.
AU  - Wynn,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3389/fpsyt.2023.1089452
L1  - internal-pdf://3263041816/Gabarron_2023.pdf
PY  - 2023
SP  - 9
T2  - Frontiers in Psychiatry
TI  - Social media interventions for autistic individuals: Systematic review
UR  - &lt;Go to ISI&gt;://WOS:000952248800001
VL  - 14
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis aimed to examine the effectiveness of psychological interventions for internalising disorders in youth when delivered in routine settings. Secondary aims were to examine the effectiveness of cognitive behavioural therapy and determine moderators of treatment response. The study was pre-registered (PROSPERO 2020 CRD42020202776). Databases were systematically searched (PsycINFO, Medline, Embase, PubMed, ERIC) in December 2022 and screened according to the PRISMA 2020 statement. Inclusion: School aged participants (4-18 years) with a primary internalising disorder; psychotherapy delivered in a routine setting (e.g. outpatient clinic, school) by setting staff; compared psychotherapy to any control in a randomised controlled trial; reported pre-to-post or pre-to-follow-up comparisons on the primary disorder according to child, parent or independent evaluator report; and was published in English. Risk of bias was assessed using the ROB 2.0 Cochrane tool. Results were synthesised using random effects to pool estimates. Risk ratios were used to analyse dichotomous data and standardised mean differences (SMD) for continuous data. Forty-five studies were included (N = 4901 participants; M = 13 years; range 8-16; SD = 2.5). Nine used waitlist control, 17 treatment as usual, 4 placebo; 15 compared psychotherapy to active control. Psychotherapy was associated with small significant effects pre- to post-treatment compared to non-active controls for anxiety (SMD = - 0.24 to 0.50) and depression (SMD = - 0.19 to 0.34) with effects differing by informant. Psychotherapy led to small significant pre-to-post-benefits in youth internalising disorders in routine settings. Results are limited by reporter type and follow-up. Copyright &copy; 2023. The Author(s).
AN  - 37059918
AU  - Wuthrich,
AU  - V.
AU  - M.
AU  - Zagic,
AU  - D.
AU  - Dickson,
AU  - S.
AU  - J.
AU  - McLellan,
AU  - L.
AU  - F.
AU  - Chen,
AU  - J.
AU  - T.
AU  - Jones,
AU  - M.
AU  - P.
AU  - Rapee,
AU  - R.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-023-00433-8
L1  - internal-pdf://2471064459/Wuthrich-2023-Effectiveness of Psychotherapy f.pdf
PY  - 2023
SP  - 14
T2  - Clinical Child &amp; Family Psychology Review
TI  - Effectiveness of Psychotherapy for Internalising Symptoms in Children and Adolescents When Delivered in Routine Settings: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37059918
UR  - https://link.springer.com/content/pdf/10.1007/s10567-023-00433-8.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - **Background**
There is a significant research gap in the field of universal, selective, and indicated prevention interventions for mental health promotion and the prevention of mental disorders. Barriers to closing the research gap include scarcity of skilled human resources, large inequities in resource distribution and utilization, and stigma.

**Objectives**
To assess the effectiveness of delivery by primary workers of interventions for the promotion of mental health and universal prevention, and for the selective and indicated prevention of mental disorders or symptoms of mental illness in low‐ and middle‐income countries (LMICs). To examine the impact of intervention delivery by primary workers on resource use and costs.

**Search methods**
We searched CENTRAL, MEDLINE, Embase, CINAHL, Global Index Medicus, PsycInfo, WHO ICTRP, and ClinicalTrials.gov from inception to 29 November 2021.

**Selection criteria**
Randomized controlled trials (RCTs) of primary‐level and/or community health worker interventions for promoting mental health and/or preventing mental disorders versus any control conditions in adults and children in LMICs

**Data collection and analysis**
Standardized mean differences (SMD) or mean differences (MD) were used for continuous outcomes, and risk ratios (RR) for dichotomous data, using a random‐effects model. We analyzed data at 0 to 1, 1 to 6, and 7 to 24 months post‐intervention. For SMDs, 0.20 to 0.49 represented small, 0.50 to 0.79 moderate, and
AU  - Purgato,
AU  - M.
AU  - Prina,
AU  - E.
AU  - Ceccarelli,
AU  - C.
AU  - Cadorin,
AU  - C.
AU  - Abdulmalik,
AU  - J.
AU  - O.
AU  - Amaddeo,
AU  - F.
AU  - Arcari,
AU  - L.
AU  - Churchill,
AU  - R.
AU  - Jordans,
AU  - M.
AU  - J.
AU  - D.
AU  - Lund,
AU  - C.
AU  - Papola,
AU  - D.
AU  - Uphoff,
AU  - E.
AU  - van
AU  - Ginneken,
AU  - N.
AU  - Tol,
AU  - W.
AU  - A.
AU  - Barbui,
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD014722.pub2
L1  - internal-pdf://3627622386/Purgato_et_al-2023-Cochrane_Database_of_System.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Primary‐level and community worker interventions for the prevention of mental disorders and the promotion of well‐being in low‐ and middle‐income countries
ER  -
TY  - JOUR
AB  - **Background**
Young people who fail to develop language as expected face significant challenges in all aspects of life. Unfortunately, language disorders are common, either as a distinct condition (e.g., Developmental Language Disorder) or as a part of another neurodevelopmental condition (e.g., autism). Finding ways to attenuate language problems through intervention has the potential to yield great benefits not only for the individual but also for society as a whole.

**Objectives**
This meta‐analytic review examined the effect of oral language interventions for children with neurodevelopmental disorders.

**Search Methods**
The last electronic search was conducted in April 2022.

**Selection Criteria**
Intervention studies had to target language skills for children from 2 to 18 years of age with Developmental Language Disorder, autism, intellectual disability, Down syndrome, Fragile X syndrome, and Williams syndrome in randomised controlled trials or quasi‐experimental designs. Control groups had to include business‐as‐usual, waiting list, passive or active conditions. However, we excluded studies in which the active control group received a different type, delivery, or dosage of another language intervention. Eligible interventions implemented explicit and structured activities (i.e., explicit instruction of vocabulary, narrative structure or grammatical rules) and/or implicit and broad activities (i.e., shared book reading, general language stimulation). The intervention studies had to assess language skills in receptive and/or expressive modalities.

**Data Collection and Analysis**
The search provided 8195 records after deduplication. Records were screened by title and abstract, leading to full‐text examinations of 448 records. We performed Correlated and Hierarchical Effects models and ran a retrospective power analysis via simulation. Publication bias was assessed via p‐curve and precision‐effect estimate.

**Main Results**
We examined 38 studies, with 46 group comparisons and 108 effects comparing pre‐/post‐tests and eight studies, with 12 group comparisons and 21 effects at follow‐up. The results showed a mean effect size of d&thinsp;=&thinsp;0.27 at the post‐test and d&thinsp;=&thinsp;0.18 at follow‐up. However, there was evidence of publication bias and overestimation of the mean effects. Effects from the meta‐analysis were significantly related to these elements: (1) receptive vocabulary and omnibus receptive measures showed smaller effect sizes relative to expressive vocabulary, grammar, expressive and receptive discourse, and omnibus expressive tests; and (2) the length of the intervention, where longer sessions conducted over a longer period of time were more beneficial than brief sessions and short‐term interventions. Neither moderators concerning participants&rsquo; characteristics (children&#039;s diagnosis, diagnostic status, age, sex, and non‐verbal cognitive ability and severity of language impairment), nor those regarding of the treatment components and implementation of the language interventions (intervention content, setting, delivery agent, session structure of the intervention or total number of sessions) reached significance. The same occurred to indicators of study quality. The risk of bias assessment showed that reporting quality for the studies examined in the review was poor.

**Authors&rsquo; Conclusions**
In sum, the current evidence base is promising but inconclusive. Pre‐registration and replication of more robust and adequately powered trials, which include a wider range of diagnostic conditions, together with more long‐term follow‐up comparisons, are needed to drive evidence‐based practice and policy.
AU  - Donolato,
AU  - E.
AU  - Enrico
AU  - Toffalini
AU  - Rogde,
AU  - K.
AU  - Nordahl‐Hansen,
AU  - A.
AU  - Lervåg,
AU  - A.
AU  - Norbury,
AU  - C.
AU  - Melby‐Lervåg,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1002/cl2.1368
L1  - internal-pdf://0324670818/CL2-19-e1368.cleaned.pdf
PY  - 2023
T2  - Campbell Systematic Reviews
TI  - Oral language interventions can improve language outcomes in children with neurodevelopmental disorders: A systematic review and meta‐analysis
ER  -
TY  - JOUR
AB  - **Context** 
Although the survival rate of cancer patients has been increasing, such patients often experience severe physical and psychological burdens due to the effects of the disease and therapy. Multiple virtual reality (VR)-based interventions have been used to help improve physical and psychological symptoms and quality of life in cancer patients. 

**Objective** 
This study aimed to assess the effects of VR-based interventions on anxiety, pain, depression, fear, distress, and quality of life in cancer patients. 

**Methods** 
We conducted systematic searches in the PubMed, Web of Science, CINAHL, EMBASE, Cochrane Library, Scopus and APA PsycINFO databases from their inception to August 16, 2022. Two reviewers independently selected studies and extracted articles that met strict inclusion and exclusion criteria. Quality assessments of the included studies were performed according to the Cochrane risk assessment tool, and data analysis was performed using RevMan 5.4 software. 

**Results** 
A total of 12 studies including 425 participants in the intervention group and 400 participants in the control group were selected for the final analysis. The results showed a significant difference between the VR and control groups for anxiety (standard mean difference [SMD] =-0.83, 95% CI-1.25 to-0.42, P&lt; 0.001), SMD = pain (SMD =-0.86, 95% CI-1.36 to-0.35, P&lt; 0.001), depression (SMD =-0.46, 95% CI-0.74 to-0.18, P = 0.001), fear (MD =-0.82, 95% CI-1.60 to-0.03, P = 0.04), and distress (SMD =-1.16, 95% CI-1.96 to-0.37, P = 0.004). However, no significant difference was observed in quality of life (SMD = 1.01, 95% CI-0.67 to 2.70, P = 0.24). 

**Conclusions**
VR interventions were effective in improving physical and psychological symptoms in cancer patients. Due to the limited number of studies, small sample sizes, and moderate to high heterogeneity, these results should be interpreted with caution. More rigorous, comprehensive and high-quality randomized controlled trials (RCTs) are needed to validate the results of this study. 

**Trial Registration** PROSPERO International Prospective Register of Systematic Reviews CRD42022304931;https://www.crd. york.ac.uk/PROSPERO/display_record.php?RecordID=304931
AN  - WOS:000981614500001
AU  - Wu,
AU  - Y.
AU  - Wang,
AU  - N.
AU  - N.
AU  - Zhang,
AU  - H.
AU  - C.
AU  - Sun,
AU  - X.
AU  - H.
AU  - Wang,
AU  - Y.
AU  - Q.
AU  - Zhang,
AU  - Y.
AU  - X.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1016/j.jpainsymman.2023.01.023
L1  - internal-pdf://2671634408/Wu-2023-Effectiveness of Virtual Reality in Sy.pdf
PY  - 2023
SP  - E467-E482
T2  - Journal of Pain and Symptom Management
TI  - Effectiveness of Virtual Reality in Symptom Management of Cancer Patients: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000981614500001
UR  - https://www.jpsmjournal.com/article/S0885-3924(23)00053-2/pdf
VL  - 65
ER  -
TY  - JOUR
AB  - There is evidence that physical activity positively influences cognition and academic outcomes in childhood. This systematic review used a three-level meta-analytic approach, which handles nested effect sizes, to assess the impact of physical activity interventions. Ninety-two randomised control trials in typically developing children (5-12 years old, N = 25,334) were identified. Control group type and intervention characteristics including duration, frequency, and teacher qualification were explored as potential moderators. Results showed physical activity interventions improved on-task behaviour with a large effect size (g = 1.04, p = 0.03 (95% CI: 0.08-2.00), very low-certainty evidence) and led to moderate improvements in creativity (g = 0.70, p &lt; 0.01 (0.20-1.20), low-certainty evidence). Small beneficial effects were found for fluid intelligence (g = 0.16, p = 0.03 (0.02, 0.30), moderate-certainty evidence) and working memory (g = 0.18, p = 0.01 (0.07-0.29), very low-certainty evidence), but no overall benefit was observed for attention, inhibitory control, planning, cognitive flexibility or academic outcomes. Heterogeneity was high, and moderator analyses indicated beneficial effects of physical activity (PA) with academic instruction of 6-10-week duration with moderate or moderate to vigorous intensity on mathematics outcomes and enriched PA programmes on language outcomes. In contrast, aerobic PA with moderate to vigorous intensity benefitted executive function outcomes. These results therefore suggest differential mechanisms of impact of different types of PA on different aspects of cognition.
AN  - WOS:000994246000001
AU  - Vasilopoulos,
AU  - F.
AU  - Jeffrey,
AU  - H.
AU  - Wu,
AU  - Y.
AU  - W.
AU  - Dumontheil,
AU  - I.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1007/s10648-023-09760-2
L1  - internal-pdf://2823874301/Vasilopoulos-2023-Multi-Level Meta-Analysis of.pdf
PY  - 2023
SP  - 38
T2  - Educational Psychology Review
TI  - Multi-Level Meta-Analysis of Physical Activity Interventions During Childhood: Effects of Physical Activity on Cognition and Academic Achievement
UR  - &lt;Go to ISI&gt;://WOS:000994246000001
UR  - https://link.springer.com/content/pdf/10.1007/s10648-023-09760-2.pdf
VL  - 35
ER  -
TY  - JOUR
AB  - **Background** 
Evidence suggests that cognitive bias modification of interpretations (CBM-I) is effective in modifying interpretation biases and has a small effect on reducing anxiety in children and adolescents. However, most evidence to date is based on studies which report anxiety or general distress using ad-hoc Likert-type or Visual Analogue Scales, which are useful but do not reliably index symptoms of clinical importance. This meta-analysis aimed to establish the effects of CBM-I for children and adolescents on both anxiety and depression using psychometrically validated symptom measures, as well as state negative affect and negative and positive interpretation bias. 

**Methods** 
We identified studies through a systematic search. To be eligible for inclusion, studies needed to target interpretation biases, not combine CBM-I with another intervention, randomly allocate participants to CBM-I or a control condition, assess a mental health outcome (i.e., anxiety or depression symptoms using validated measures or state measures of negative affect) and/or interpretation bias and have a mean age less than 18 years. 

**Results** 
We identified 36 studies for inclusion in the meta-analysis. CBM-I had a small and non-significant unadjusted effect on anxiety symptoms (g = 0.16), no effect on depression symptoms (g = -0.03), and small and non-significant unadjusted effects on state negative affect both at post-training (g = 0.16) and following a stressor task (g = 0.23). In line with previous findings, CBM-I had moderate to large unadjusted effects on negative and positive interpretations (g = 0.78 and g = 0.52). No significant moderators were identified. 

**Conclusions** 
CBM-I is effective at modifying interpretation bias, however there were no effects on mental health outcomes. The substantial variability across studies and paucity of studies using validated symptom measures highlight the need to establish randomized controlled trial protocols that evaluate CBM-I in clinical youth samples to determine its future as a clinical intervention.
AN  - 2024-29000-001
AU  - Sicouri,
AU  - G.
AU  - Daniel,
AU  - E.
AU  - K.
AU  - Spoelma,
AU  - M.
AU  - J.
AU  - Salemink,
AU  - E.
AU  - McDermott,
AU  - E.
AU  - A.
AU  - Hudson,
AU  - J.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/jcv2.12207
L1  - internal-pdf://4292821790/Sicouri-2023-Cognitive bias modification of in.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Jcpp Advances
TI  - Cognitive bias modification of interpretations for anxiety and depression in children and adolescents: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2024-29000-001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcv2.12207?download=true
ER  -
TY  - JOUR
AB  - To determine the efficacy of intervention programs for young children (4-9 years) with emerging mental health needs, we conducted a review of meta-analytic and systematic reviews of the intervention literature. Of 41,061 abstracts identified and 15,076 screened, 152 review articles met the inclusion criteria. We reviewed interventions across multiple disciplines targeting: (1) general mental health concerns; (2) internalizing symptoms; (3) externalizing symptoms; (4) anxiety; (5) depression; (6) trauma; (7) symptoms of attention-deficit/hyperactivity disorder; and (8) mental health concerns associated with autism spectrum disorder. Substantial evidence was found for the efficacy of behavioral and cognitive behavioral interventions for general mental health concerns, externalizing symptoms (generally, as well as ADHD, conduct, and other behavioral symptoms) and internalizing symptoms (generally, as well as anxiety) aged 4-9 years. Emerging evidence was identified for interventions targeting trauma symptoms, depression symptoms, and social, emotional and behavioral symptoms in autism spectrum disorder in children aged 4-9 years. Currently there is only limited emerging evidence regarding non-behavioral or non-cognitive behavioral interventions for programs targeting children ages 4-9 years where the aim is to deliver an evidence-based program to improve child social, emotional and/or behavioral functioning. Given the recent rises in mental health needs reported in children, targeted behavioral-and/or cognitive behavior therapy-based interventions should be made widely available to children (and their families) who experience elevated symptoms.
AN  - WOS:001032293000001
AU  - Hudson,
AU  - J.
AU  - L.
AU  - Minihan,
AU  - S.
AU  - Chen,
AU  - W.
AU  - T.
AU  - Carl,
AU  - T.
AU  - Fu,
AU  - M.
AU  - Tully,
AU  - L.
AU  - Kangas,
AU  - M.
AU  - Rosewell,
AU  - L.
AU  - McDermott,
AU  - E.
AU  - A.
AU  - Wang,
AU  - Y.
AU  - W.
AU  - Stubbs,
AU  - T.
AU  - Martiniuk,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s10567-023-00443-6
L1  - internal-pdf://1835960611/Hudson-2023-Interventions for Young Children&#039;s.pdf
PY  - 2023
SP  - 49
T2  - Clinical Child and Family Psychology Review
TI  - Interventions for Young Children&#039;s Mental Health: A Review of Reviews
UR  - &lt;Go to ISI&gt;://WOS:001032293000001
UR  - https://link.springer.com/content/pdf/10.1007/s10567-023-00443-6.pdf
ER  -
TY  - JOUR
AB  - Psychodrama and drama therapy are organized health professions where credentialed professionals intentionally employ experiential drama processes and techniques to ameliorate health and well-being within a therapeutic relationship. These drama-based therapies are used for mental health treatment across a range of clients and in various healthcare settings. The aims of this systematic review and meta-analysis were to (a) aggregate and synthesize the evidence on drama-based therapies, (b) assess the strength of the effects of drama-based therapies on mental health outcomes, and (c) examine which outcome, study, sample, or intervention characteristics moderated the strength of the effect on the outcomes. Inclusion criteria were randomized control trials and clinical control trials, mental health outcomes, and therapy interventions. The protocol for this study was registered at PROSPERO and seven databases were searched: Cochrane Library, Web of Science, Embase, Wiley Online Library, PubMed, PsycINFO, and Scopus. Risk of bias in the included studies was assessed and a multilevel meta-analysis was performed, containing 30 controlled studies, 144 effect sizes, and 1,567 participants. The results showed an overall medium effect of drama-based therapies on both psychological and behavioral mental health outcomes (d = .501, [.36, .64]). There was no statistically significant difference between psychodrama and drama therapy, and other selected characteristics did not have a statistically significant impact on treatment effectiveness. Although this meta-analysis was not restricted to randomized controlled trails, these findings suggest that group psychodrama and drama therapy are effective in contributing to clients&#039; mental health, with similar overall effects as shown in other psychotherapies. Implications for future research are discussed. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AU  - Orkibi,
AU  - H.
AU  - Keisari,
AU  - S.
AU  - Sajnani,
AU  - N.
AU  - L.
AU  - de
AU  - Witte,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/aca0000582
L1  - internal-pdf://3417149463/2023-66168-001.cleaned.pdf
PY  - 2023
SP  - No-Specified
T2  - Psychology of Aesthetics, Creativity, and the Arts
TI  - Effectiveness of drama-based therapies on mental health outcomes: A systematic review and meta-analysis of controlled studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=psyc21&amp;NEWS=N&amp;AN=2023-66168-001
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis aimed to systematically evaluate the effect of physical activity (PA) on inhibitory function in children with ADHD. Experimental studies on the effect of PA on the inhibitory function of children with ADHD were retrieved. The data were obtained from PubMed, The Cochrane Library, Web of Science, EBSCO (MEDLINE, APA Psyclnfo, ERIC), Embase, Scopus, and ProQuest. The search period was from the date of inception of the respective databases to 4 May 2022, and Reviewer Manager software (version 5.3) was used for analysis. Eleven articles and 713 samples were included in the meta-analysis. Results revealed that PA can significantly improve the inhibitory function of children with ADHD (SMD = 0.78, 95% CI: 0.45-1.10, p &lt; 0.001). Subgroup analysis showed that the effectiveness of PA as an intervention in improving the inhibitory function of children with ADHD was moderated by the frequency, intensity, duration, type, and length of intervention. Based on the findings, PA can effectively improve interference suppression inhibitory function in children with ADHD. Longitudinal open-skill exercise for 60 min or more, two times/week has the best effect on improving inhibitory function in children with ADHD.
AN  - 36673793
AU  - Wang,
AU  - M.
AU  - Yang,
AU  - X.
AU  - Yu,
AU  - J.
AU  - Zhu,
AU  - J.
AU  - Kim,
AU  - H.
AU  - D.
AU  - Cruz,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/ijerph20021032
L1  - internal-pdf://0130675326/Wang-2023-Effects of Physical Activity on Inhi.pdf
PY  - 2023
SP  - 06
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Effects of Physical Activity on Inhibitory Function in Children with Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36673793
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-20-01032/article_deploy/ijerph-20-01032.pdf?version=1672993347
VL  - 20
ER  -
TY  - JOUR
AB  - AIMS: To evaluate the effects of maternal sound stimulation on preterm infants. 

BACKGROUND: With an increased focus of studies on maternal sound stimulation for preterm infants, there is a need for an up-to-date systematic review and meta-analysis of randomized controlled trials to measure the effects of maternal sound stimulation on preterm infants. 

DESIGN: A systematic review and meta-analysis. 

DATA SOURCES: We searched PubMed, EMBASE, the Cochrane Library, CINAHL Complete, VIP Journal Integration Platform, China National Knowledge Infrastructure, Wanfang Data and China Biology Medicine disc from database establishment to 28 April 2021. 

REVIEW METHODS: We conducted the meta-analysis using Review Manager 5.3. Integrative description was used for data that were not suitable for meta-analysis. 

RESULTS: A total of 380 studies between 1979 and 2021 were retrieved and 26 were included in this systematic review. Maternal sound stimulation could significantly reduce the pain level and increase the comfort level of preterm infants during a painful procedure. Compared with routine care, maternal sound stimulation could help preterm infants achieve better physiological stability by reducing their heart rate and increasing their oxygen saturation. 

CONCLUSION: Maternal sound stimulation is a feasible and effective intervention for preterm infants, which is highly recommended in the clinical setting. Copyright &copy; 2022 John Wiley &amp; Sons Australia, Ltd.
AN  - 35187754
AU  - Li,
AU  - Y.
AU  - Zhang,
AU  - J.
AU  - Yang,
AU  - C.
AU  - Xia,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/ijn.13039
L1  - internal-pdf://3979947245/Li-2023-Effects of maternal sound stimulation.pdf
PY  - 2023
SP  - e13039
T2  - International Journal of Nursing Practice
TI  - Effects of maternal sound stimulation on preterm infants: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35187754
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijn.13039?download=true
VL  - 29
ER  -
TY  - JOUR
AB  - Selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs) show similar efficacy as treatments for anxiety, obsessive-compulsive, and stress-related disorders. Hence, comparisons of adverse event rates across medications are an essential component of clinical decision-making. We aimed to compare patterns of adverse events associated with SSRIs and SNRIs in the treatment of children and adults diagnosed with these disorders through a network meta-analysis. We searched MEDLINE, PsycINFO, Embase, Cochrane, websites of regulatory agencies, and international registers from inception to 09 September 2022, for randomized controlled trials assessing the efficacy of SSRIs or SNRIs. We analyzed the proportion of participants experiencing at least one adverse event and incidence rates of 17 specific adverse events. We estimated incidence rates and odds ratios through network meta-analysis with random effects and three-level models. We analyzed 799 outcome measures from 80 studies (n = 21 338). Participants in medication groups presented higher rates of adverse events (80.22%, 95% CI 76.13-83.76) when compared to placebo groups (71.21%, 67.00-75.09). Nausea was the most common adverse event (25.71%, CI 23.96-27.54), while weight change was the least common (3.56%, 1.68-7.37). We found higher rates of adverse events of medications over placebo for most medications, except sertraline and fluoxetine. We found significant differences between medications for overall tolerability and for autonomic, gastrointestinal, and sleep-related symptoms. Adverse events are a common reason that patients discontinue SSRIs and SNRIs. Results presented here guide clinical decision-making when clinicians weigh one medication over another. This might improve treatment acceptability and compliance.
AN  - 37278215
AU  - Gosmann,
AU  - N.
AU  - P.
AU  - Costa,
AU  - M.
AU  - A.
AU  - Jaeger,
AU  - M.
AU  - B.
AU  - Frozi,
AU  - J.
AU  - Spanemberg,
AU  - L.
AU  - Manfro,
AU  - G.
AU  - G.
AU  - Cortese,
AU  - S.
AU  - Cuijpers,
AU  - P.
AU  - Pine,
AU  - D.
AU  - S.
AU  - Salum,
AU  - G.
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1017/S0033291723001630
L1  - internal-pdf://0917230375/Gosmann_2023.cleaned.pdf
PY  - 2023
SP  - 1-10
T2  - Psychological Medicine
TI  - Incidence of adverse events and comparative tolerability of selective serotonin reuptake inhibitors, and serotonin and norepinephrine reuptake inhibitors for the treatment of anxiety, obsessive-compulsive, and stress disorders: a systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37278215
UR  - https://www.cambridge.org/core/journals/psychological-medicine/article/abs/incidence-of-adverse-events-and-comparative-tolerability-of-selective-serotonin-reuptake-inhibitors-and-serotonin-and-norepinephrine-reuptake-inhibitors-for-the-treatment-of-anxiety-obsessivecompulsive-and-stress-disorders-a-systematic-review-and-network-metaanalysis/591C2978D003E9CCE0009355295767A0
ER  -
TY  - JOUR
AB  - **Importance:** 
Depression is the second most prevalent mental disorder among children and adolescents, yet only a small proportion seek or receive disorder-specific treatment. Physical activity interventions hold promise as an alternative or adjunctive approach to clinical treatment for depression. 

**Objective:** 
To determine the association of physical activity interventions with depressive symptoms in children and adolescents. Data Sources: PubMed, CINAHL, PsycINFO, EMBASE, and SPORTDiscus were searched from inception to February 2022 for relevant studies written in English, Chinese, or Italian. 

**Study Selection:** 
Two independent researchers selected studies that assessed the effects of physical activity interventions on depressive symptoms in children and adolescents compared with a control condition. 

**Data Extraction and Synthesis:** 
A random-effects meta-analysis using Hedges g was performed. Heterogeneity, risk of bias, and publication bias were assessed independently by multiple reviewers. Meta-regressions and sensitivity analyses were conducted to substantiate the overall results. The study followed the PRISMA reporting guideline.

**Main Outcomes and Measures:** 
The main outcome was depressive symptoms as measured by validated depression scales at postintervention and follow-up. Results: Twenty-one studies involving 2441 participants (1148 [47.0%] boys; 1293 [53.0%] girls; mean [SD] age, 14 [3] years) were included. Meta-analysis of the postintervention differences revealed that physical activity interventions were associated with a reduction in depressive symptoms compared with the control condition (g = -0.29; 95% CI, -0.47 to -0.10; P = .004). Analysis of the follow-up outcomes in 4 studies revealed no differences between the physical activity and control groups (g = -0.39; 95% CI, -1.01 to 0.24; P = .14). Moderate study heterogeneity was detected (Q = 53.92; df = 20; P &lt; .001; I2 = 62.9% [95% CI, 40.7%-76.8%]). The primary moderator analysis accounting for total physical activity volume, study design, participant health status, and allocation and/or assessment concealment did not moderate the main treatment effect. Secondary analyses demonstrated that intervention (ie, &lt;12 weeks in duration, 3 times per week, unsupervised) and participant characteristics (ie, aged &gt;=13 years, with a mental illness and/or depression diagnosis) may influence the overall treatment effect. 

**Conclusions and Relevance:** 
Physical activity interventions may be used to reduce depressive symptoms in children and adolescents. Greater reductions in depressive symptoms were derived from participants older than 13 years and with a mental illness and/or depression diagnosis. The association with physical activity parameters such as frequency, duration, and supervision of the sessions remains unclear and needs further investigation.
AN  - 36595284
AU  - Recchia,
AU  - F.
AU  - Bernal,
AU  - J.
AU  - D.
AU  - K.
AU  - Fong,
AU  - D.
AU  - Y.
AU  - Wong,
AU  - S.
AU  - H.
AU  - S.
AU  - Chung,
AU  - P.
AU  - K.
AU  - Chan,
AU  - D.
AU  - K.
AU  - C.
AU  - Capio,
AU  - C.
AU  - M.
AU  - Yu,
AU  - C.
AU  - C.
AU  - W.
AU  - Wong,
AU  - S.
AU  - W.
AU  - S.
AU  - Sit,
AU  - C.
AU  - H.
AU  - P.
AU  - Chen,
AU  - Y.
AU  - J.
AU  - Thompson,
AU  - W.
AU  - R.
AU  - Siu,
AU  - P.
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1001/jamapediatrics.2022.5090
L1  - internal-pdf://2915227758/Recchia-2023-Physical Activity Interventions t.pdf
PY  - 2023
SP  - 03
T2  - Jama Pediatrics
TI  - Physical Activity Interventions to Alleviate Depressive Symptoms in Children and Adolescents: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36595284
UR  - https://jamanetwork.com/journals/jamapediatrics/articlepdf/2799811/jamapediatrics_recchia_2023_oi_220081_1675462465.12338.pdf
VL  - 03
ER  -
TY  - JOUR
AB  - The aim of this systematic review was to determine the efficacy of very early interventions for infants and toddlers at increased likelihood of or diagnosed with autism for autism symptomatology, developmental outcomes and/or neurocognitive markers. Eight databases were searched (14 April 2022) with inclusion criteria: (i) RCTs with care as usual (CAU) comparison group, (ii) participants at increased likelihood of or diagnosed with autism and aged &lt;24 months corrected age (CA), (iii) parent-mediated and/or clinician directed interventions, and (iv) outcome measures were autism symptomatology, cognition, language, adaptive skills, or neurocognitive assessments (EEG and eye tracking). Quality was assessed using Risk of Bias 2 and GRADE. Nineteen publications from 12 studies reported on 715 infants and toddlers. There was low to moderate certainty evidence that clinician-assessed outcomes did not show significant treatment effects for: autism symptomatology (ADOS CSS: MD -0.08, 95% CI -0.61, 0.44, p = 0.75), cognitive outcome (Mullen Scales of Early Learning-Early Learning Composite (MSEL-ELC): SMD 0.05, 95% CI -0.19, 0.29, p = 0.67), receptive language (MSEL-Receptive Language: SMD 0.04, 95% CI -0.21, 0.3, p = 0.74) or expressive language (MSEL-Expressive Language: SMD 0.06, 95% CI -0.1, 0.23, p = 0.45). Neurocognitive outcomes (EEG and eye tracking) were heterogeneous, with inconsistent findings. There is low to moderate certainty evidence that very early interventions have limited impact on neurodevelopmental outcomes by age 3 years. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-64082-001
AU  - McGlade,
AU  - A.
AU  - Whittingham,
AU  - K.
AU  - Barfoot,
AU  - J.
AU  - Taylor,
AU  - L.
AU  - Boyd,
AU  - R.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/aur.2924
L1  - internal-pdf://3874566341/McGlade-2023-Efficacy of very early interventi.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Autism Research
TI  - Efficacy of very early interventions on neurodevelopmental outcomes for infants and toddlers at increased likelihood of or diagnosed with autism: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-64082-001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aur.2924?download=true
ER  -
TY  - JOUR
AB  - The purpose of this paper is to explore treatment effects associated with counseling and therapy interventions (CTIs) for children ages 3- 12 and to understand the role of common factors (CFs) in child CTIs. We conducted a systematic review and metaanalysis of CTIs for children to explore CF and clinically relevant outcomes based on the sequential model by Lambert and Ogles. The 59 effect sizes included in the analysis of the relationship between CTI for youth and treatment outcomes (N = 36) yielded a mean effect size of 0.548 (CI95 = 0.413, 0.683), tau2 = 0.092, p &lt; .001, indicative of a medium effect size. There were no statistically significant differences detected between study outcomes and CF, Q(2) = 5.240, p = .073. However, when inspecting effect sizes estimates between groups, interventions that were associated with learning (g = 0.623, k = 20) and action (g = 0.557, k = 35) trended toward larger magnitudes compared to support alone (g = 0.245, k = 4). Implications for counseling and future research are provided. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-79499-001
AU  - Warwick,
AU  - L.
AU  - A.
AU  - Lenz,
AU  - A.
AU  - Branch,
AU  - M.
AU  - L.
AU  - Lemberger-Truelove,
AU  - M.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/23727810.2023.2215157
L1  - internal-pdf://3496051699/Warwick-2023-A meta-analysis of common factors.pdf
PY  - 2023
SP  - 170-191
T2  - Journal of Child and Adolescent Counseling
TI  - A meta-analysis of common factors in child therapy interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2023-79499-001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/23727810.2023.2215157
VL  - 9
ER  -
TY  - JOUR
AB  - Many studies focus on the impact of equine assisted services (EAS) on social skills in autism spectrum disorder (ASD) but existing data are not consensual and the only available meta-analysis included only three studies and did not consider the social responsiveness scale (SRS). This meta-analysis aims to measure the impact of EAS on social skills in ASD. Using Pubmed, Embase, Web of Science and the Cochrane Library, the means and standard deviations of every available SRS post-intervention scores in each participant group were collected from the five selected randomised controlled trials with 240 participants. An EAS significant beneficial impact was found for the total SRS score, social communication and social cognition. A tendency to a significant impact was found for social awareness and social motivation. No significant difference was shown for autistic mannerisms. This metaanalysis shows a significant beneficial impact of EAS for several social skills in ASD. Further randomised controlled trials are required to complement these results and expand the knowledge on the field of possibilities of this care in ASD.
AN  - WOS:001055071200001
AU  - Madigand,
AU  - J.
AU  - Rio,
AU  - M.
AU  - Vandevelde,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.pnpbp.2023.110765
L1  - internal-pdf://4143648013/Madigan_2023.pdf
PY  - 2023
SP  - 9
T2  - Progress in Neuro-Psychopharmacology &amp; Biological Psychiatry
TI  - Equine assisted services impact on social skills in autism spectrum disorder: A meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001055071200001
UR  - https://www.sciencedirect.com/science/article/pii/S0278584623000519?via%3Dihub
VL  - 125
ER  -
TY  - JOUR
AB  - This review aims to systematically summarize existing evidence to determine the effectiveness of cognitive-based interventions (CBIs) on psychological health and well-being among parents of children with developmental disabilities (DD). Six databases were searched to identify eligible randomized controlled trials (RCTs) from their inception to April 2023. The revised Cochrane Risk of Bias tool for RCTs was applied to assess the risk of bias and the certainty of evidence was evaluated using the Grading of Recommendation, Assessment, Development and Evaluation. Meta-analyses were conducted using a random-effects model. Twenty-five RCTs involving 1915 participants were identified. The results indicated that CBIs reduced parental stress levels (Hedges&#039; g = - 0.69), depressive symptoms (g = - 0.95), anxiety levels (g = - 0.78), and parental distress (g = - 0.29), and improved parental well-being (g = 0.62) and parent-child relationships (g = 0.43) postintervention compared with the active/inactive control groups. Subgroup analysis of the effectiveness of interventions using mindfulness-based interventions and cognitive behavioural therapy showed positive effects. The favourable intervention duration and participant targets were also identified in this review. Furthermore, the effects of CBIs were impacted by the different types of DD among the children. This review highlighted the positive effects of CBIs on parental stress levels, depressive symptoms, anxiety levels, parental distress levels, parental well-being levels, and parent-child relationships. Future well-designed RCTs are needed to further investigate the effects of MBIs and CBT interventions on children with DD and their parents, as well as the factors and mechanisms of action affecting the efficacy of these interventions.
AN  - 37668850
AU  - Li,
AU  - S.
AU  - Yong,
AU  - Y.
AU  - Li,
AU  - Y.
AU  - Li,
AU  - J.
AU  - Xie,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-023-06063-x
L1  - internal-pdf://0402457714/Li-2023-Cognitive-Based Interventions for Impr.pdf
PY  - 2023
SP  - 05
T2  - Journal of Autism &amp; Developmental Disorders
TI  - Cognitive-Based Interventions for Improving Psychological Health and Well-Being for Parents of Children with Developmental Disabilities: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37668850
UR  - https://link.springer.com/content/pdf/10.1007/s10803-023-06063-x.pdf
VL  - 05
ER  -
TY  - JOUR
AB  - **BAKGRUNN**
Treatment Foster Care Oregon (TFCO) er en behandlingsmetode for ungdommer med alvorlige atferdsvansker og deres familier. Overordnet er målene å oppnå gode behandlingsresultater på ungdommens vansker, og at ungdommene skal kunne bo hjemme hos foreldrene. TFCO er en multisystemisk, koordinert behandlingsform, der man arbeider med flere relevante arenaer for ungdommen parallelt, som for eksempel. familie, skole, psykisk helsehjelp og fritid. I behandlingsperioden bor ungdommen midlertidig i et fosterhjem, for så å flytte gradvis hjem til foreldrene. Nasjonalt utviklingssenter for barn og unge (NUBU) som har ansvaret for metoden i Norge.

**METODE**
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

**RESULTATER**
Resultatene består av en vurdering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. I denne kunnskapsoppsummeringen identifiserte vi 4 nordiske effektstudier samt 14 internasjonale oppsummeringer og vurderinger i databaser om tiltaket. Samlet sett synes studiene å kunne dokumentere effekter på kriminalitet, antall dager i innelåste betingelser, negativ atferd og rusproblemer. Det er noe mer uklart om tiltaket har effekter på psykososiale utfallsmål.

**KONKLUSJON**
TFCO klassifiseres som et tiltak på nivå 4 som et tiltak med tilfredsstillende dokumentasjon på effekt.
AU  - Eng,
AU  - H.
AU  - Handegård,
AU  - B.
AU  - H.
AU  - Patras,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /post_tiltak_arkiv/tfco-treatment-foster-care-oregon-1-utg/
L1  - internal-pdf://2656179773/TFCO-1-utg.cleaned.pdf
PY  - 2023
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: TFCO &ndash; Treatment Foster Care Oregon (1. utg.)
ER  -
TY  - JOUR
AB  - Background:
Depression and anxiety contribute to an estimated 74.6 million years of life with disability, and 80% of this burden occurs in low- and middle-income countries (LMICs), where there is a large gap in care.

Objective:
We aimed to systematically synthesize available evidence and quantify the effectiveness of digital mental health interventions in reducing depression and anxiety in LMICs.

Methods:
In this systematic review and meta-analysis, we searched PubMed, Embase, and Cochrane databases from the inception date to February 2022. We included randomized controlled trials conducted in LMICs that compared groups that received digital health interventions with controls (active control, treatment as usual, or no intervention) on depression or anxiety symptoms. Two reviewers independently extracted summary data reported in the papers and performed study quality assessments. The outcomes were postintervention measures of depression or anxiety symptoms (Hedges g). We calculated the pooled effect size weighted by inverse variance.

Results:
Among 11,196 retrieved records, we included 80 studies in the meta-analysis (12,070 participants n=6052, 50.14% in the intervention group and n=6018, 49.85% in the control group) and 96 studies in the systematic review. The pooled effect sizes were &minus;0.61 (95% CI &minus;0.78 to &minus;0.44; n=67 comparisons) for depression and &minus;0.73 (95% CI &minus;0.93 to &minus;0.53; n=65 comparisons) for anxiety, indicating that digital health intervention groups had lower postintervention depression and anxiety symptoms compared with controls. Although heterogeneity was considerable (I2=0.94 for depression and 0.95 for anxiety), we found notable sources of variability between the studies, including intervention content, depression or anxiety symptom severity, control type, and age. Grading of Recommendations, Assessments, Development, and Evaluation showed that the evidence quality was overall high.

Conclusions:
Digital mental health tools are moderately to highly effective in reducing depression and anxiety symptoms in LMICs. Thus, they could be effective options to close the gap in depression and anxiety care in LMICs, where the usual mental health care is minimal.

Trial Registration:
PROSPERO CRD42021289709; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=289709
AN  - 2023-88040-001
AU  - Kim,
AU  - Jiyeong
AU  - Aryee,
AU  - Lois
AU  - M.
AU  - Bang,
AU  - Heejung
AU  - Prajogo,
AU  - Steffi
AU  - Choi,
AU  - Yong
AU  - K.
AU  - Hoch,
AU  - Jeffrey
AU  - S.
AU  - Prado,
AU  - Elizabeth
AU  - L.
DB  - April 24.enl
DO  - /10.2196/43066
L1  - internal-pdf://0143750493/PDF.cleaned (2).pdf
PY  - 2023
T2  - JMIR Mental Health Vol 10, 2023, ArtID e43066
TI  - Effectiveness of digital mental health tools to reduce depressive and anxiety symptoms in low- and middle-income countries: Systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.2196%2f43066
VL  - 10
ER  -
TY  - JOUR
AB  - **Purpose:** 
This review aimed to investigate the effectiveness of digital school-based mental health interventions for adolescents in Sub-Saharan Africa. 

**Method:**
The authors conducted a comprehensive search of digital school-based mental health interventions to identify studies conducted in Sub-Saharan Africa targeting adolescents between the ages of (10-19) years. Peer-reviewed studies published in English between 2009 and May 2023 were obtained through electronic bibliographic databases. 

**Result:** 
Only one study met the full inclusion criteria for this review. The included study tested a digital mental health intervention (&quot;Shamiri Digital&quot;) for treating depression, anxiety, and well-being in adolescents. The &quot;Shamiri Digital&quot; intervention demonstrated positive outcomes on depressive symptoms within the full sample. 

**Discussion:** 
The dearth of studies investigating digital mental health solutions for adolescents in low-income countries demonstrates a critical gap in intervention and research for adolescent mental health in resource constrictive settings
AN  - WOS:001075325500001
AU  - Abura-Meerdink,
AU  - G.
AU  - A.
AU  - Albright,
AU  - D.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1177/10497315231201140
L1  - internal-pdf://2291863384/abura-meerdink-albright-2023-effectiveness-of-.pdf
PY  - 2023
SP  - 10
T2  - Research on Social Work Practice
TI  - Effectiveness of Adolescent School-Based Digital Mental Health Interventions: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001075325500001
ER  -
TY  - JOUR
AB  - BACKGROUND: Grief in young people is common and associated with symptoms of anxiety and depression, yet grief interventions for this age group are under-researched.

METHOD: We conducted a systematic review and meta-analysis to examine the efficacy of grief interventions in young people. The process was co-designed with young people and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PsycINFO, Medline, and Web of Science databases were searched in July 2021 (updated December 2022).

RESULTS: We extracted results from 28 studies of grief interventions with young people (14-24 years) that measured anxiety and/or depression (N = 2803 participants, 60 % girls/women). Cognitive behavior therapy (CBT) for grief demonstrated a large effect for anxiety and medium effect for depression. A meta-regression indicated that CBT for grief that included a higher degree of CBT strategies, was not trauma focused, had &gt;10 sessions, offered on an individual basis, and did not involve parents, was associated with larger effect sizes for anxiety. Supportive therapy had a moderate effect for anxiety and a small-moderate effect for depression. Writing interventions were not effective for anxiety or depression., LIMITATIONS: Studies are limited in number and there were few randomized controlled studies.

CONCLUSIONS: Findings indicate that CBT for grief is an effective intervention for reducing symptoms of anxiety and depression in young people experiencing grief. CBT for grief should be offered as the first line treatment for grieving young people experiencing anxiety and depression.

PROTOCOL REGISTRATION: PROSPERO (registration number CRD42021264856). Copyright &copy; 2023 The Authors. Published by Elsevier B.V. All rights reserved.
AU  - Breen,
AU  - L.
AU  - J.
AU  - Greene,
AU  - D.
AU  - Rees,
AU  - C.
AU  - S.
AU  - Black,
AU  - A.
AU  - Cawthorne,
AU  - M.
AU  - Egan,
AU  - S.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2023.05.032
L1  - internal-pdf://1760462138/Breen_2023.pdf
PY  - 2023
SP  - 289-297
T2  - Journal of Affective Disorders
TI  - A co-designed systematic review and meta-analysis of the efficacy of grief interventions for anxiety and depression in young people
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37196936
UR  - https://www.sciencedirect.com/science/article/pii/S0165032723006663?via%3Dihub
VL  - 335
ER  -
TY  - JOUR
AB  - The aim of this systematic review and meta-analysis was to provide an overview of existing controlled trials focusing on the impact of multiple family therapy (MFT) on mental health problems and family functioning, and to examine the efficacy of MFT. Relevant studies were selected following a screening of 3376 studies identified by a systematic search of seven databases. The following data were extracted: participant characteristics, program characteristics, study characteristics, and information of mental health problems and/or family functioning. A total of 31 peer-reviewed, English, controlled studies evaluating the effect of MFT were included in the systematic review. Sixteen studies presenting 16 trials were included in the meta-analysis. All but one of the studies was at risk of bias, with problems concerning confounding, selection of participants and missing data. The findings confirm that MFT is offered in diverse settings, with studies presenting a variety of therapeutic modalities, focal problems, and populations. Individual studies reported some positive findings, including improvements in mental health, vocational outcomes, and social functioning. The findings of the meta-analysis suggest that MFT is associated with improvements in symptoms of schizophrenia. However, this effect was found not to be significant due to the large amount of heterogeneity. In addition, MFT was associated with small improvements in family functioning. We found little evidence to suggest that MFT successfully alleviates mood and conduct problems. To conclude, more methodologically rigorous research is needed to further examine the potential benefits of MFT, as well as the working mechanisms and core components of MFT.
AN  - WOS:000959209700001
AU  - van
AU  - Es,
AU  - C.
AU  - M.
AU  - El
AU  - Khoury,
AU  - B.
AU  - van
AU  - Dis,
AU  - E.
AU  - A.
AU  - M.
AU  - te
AU  - Brake,
AU  - H.
AU  - van
AU  - Ee,
AU  - E.
AU  - Boelen,
AU  - P.
AU  - A.
AU  - Mooren,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1111/famp.12876
L1  - internal-pdf://2308075442/van Es-The effect of multiple family therapy o.pdf
PY  - 2023
SP  - 16
T2  - Family Process
TI  - The effect of multiple family therapy on mental health problems and family functioning: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000959209700001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/famp.12876?download=true
ER  -
TY  - JOUR
AB  - **Background:** 
Appropriately selected complementary therapies, such as virtual reality (VR) and active video games (AVG), provide support to young patients during the process of cancer treatment. Therefore, this systematic review with meta-analysis aimed to analyze the effects of VR and AVG on fear, physical functions, and quality of life.

**Methods:** 
A systematic search was performed independently in Scopus, PubMed, Embase, Web of Science and Cochrane Library electronic databases for relevant randomized controlled and crossover studies. From a total of 5,963 records, 11 met the inclusion criteria. After full-text screening two publications were excluded, yet six studies were included in the quantitative analysis because three studies had a large discrepancy in their measured outcomes. For methodological quality assessments, the RoB2 software program was used, while RevMan 5.4.1 was used for statistical analysis and meta-analysis. Standard Mean Difference (SMD) outcome measures were used for the analysis. Statistical heterogeneity was assessed using the I2 statistic with a cut-off value of 50% considering intervention and outcome measures.

**Results:** 
Our systematic review includes six randomized controlled studies and three randomized crossover studies. The participants represented both sexes and were children and adolescents (&lt;18 years old) with a diagnosis of cancer. The analysis of the results allows for a careful conclusion that VR has the potential to become an accessory tool in rehabilitation and oncologic treatment. All of the included studies noted a significant advantage of this intervention.

**Conclusion:** 
VR has the potential to be an effective and important tool in the oncologic treatment of children. VR immerses the patient, and as a result, produces a distraction that effectively reduces pain associated with standard oncologic care procedures in children. However, this systematic review and meta-analysis highlights the need for more research into the use of VR as support for pediatric oncologic care., 

Systematic review registration: PROSPERO database (https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=319000), CRD42022319000. Copyright &copy; 2023 Czech, Rutkowski, Kowaluk, Kiper and Malicka.
AU  - Czech,
AU  - O.
AU  - Rutkowski,
AU  - S.
AU  - Kowaluk,
AU  - A.
AU  - Kiper,
AU  - P.
AU  - Malicka,
AU  - I.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpubh.2023.1039720
L1  - internal-pdf://1257275527/Czech-2023-Virtual reality in chemotherapy sup.pdf
PY  - 2023
SP  - 1039720
T2  - Frontiers in Public Health
TI  - Virtual reality in chemotherapy support for the treatment of physical functions, fear, and quality of life in pediatric cancer patients: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medl&amp;NEWS=N&amp;AN=37124795
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10130570/pdf/fpubh-11-1039720.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - BACKGROUND: Physical activity (PA) is often used to support the development of young children (&lt;5 years) with disabilities. The effectiveness of PA as an occupational therapy (OT) treatment approach in this population has not yet been systematically examined. AIMS: This research aimed to explore the uses and effectiveness of OT PA interventions on developmental indicators in young children with developmental disabilities. 

METHODS: A systematic review of peer-reviewed publications (from 2000 onward) across six electronic databases was conducted. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) framework was used to assess study quality. Narrative synthesis (vote counting and structured reporting of effects) was employed to summarize the findings. 

RESULTS: Eight studies with heterogenous interventions were included. Evidence demonstrated positive trends of participation in the PA interventions on physical, cognitive, and social-emotional indicators, with significance varying. There was no association between interventions and communication indicators or negative effects related to participation in the interventions. Overall, the studies were low-quality when judged by GRADE. 

CONCLUSIONS: PA may be a promising avenue for OT interventions among young children with developmental disabilities. Rigorous research is needed to determine the magnitude of effect PA has on developmental indicators.
AN  - 37069785
AU  - Taylor,
AU  - L.
AU  - G.
AU  - Primucci,
AU  - M.
AU  - Irwin,
AU  - J.
AU  - D.
AU  - Teachman,
AU  - G.
AU  - Tucker,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/01942638.2023.2199836
L1  - internal-pdf://1386960087/Taylor-2023-The Uses and Effectiveness of Occu.pdf
PY  - 2023
SP  - 1-22
T2  - Physical &amp; Occupational Therapy in Pediatrics
TI  - The Uses and Effectiveness of Occupational Therapy Physical Activity Interventions in Young Children with Developmental Disabilities: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37069785
UR  - https://www.tandfonline.com/doi/full/10.1080/01942638.2023.2199836
UR  - https://www.tandfonline.com/doi/pdf/10.1080/01942638.2023.2199836
ER  -
TY  - JOUR
AB  - BACKGROUND: Anxiety and depression are common debilitating mental health issues in families of children with chronic health conditions. It is essential to consider the mediating role of caregivers between children and healthcare workers. Previous research has evaluated the effectiveness of caregiver engagement interventions in reducing anxiety and depression in chronically ill children and their caregivers, but their overall impact awaits a synthesis of the available evidence.

METHODS: We performed a comprehensive search using PubMed, Embase, Web of Science, Cochrane Library, Ovid, PsycINFO, APA PsycArticles, and Cumulative Index of Nursing and Allied Health Literature (CINAHL).

RESULTS: Twenty-nine studies were included. The results demonstrated that caregiver engagement interventions significantly decreased anxiety (standardized mean difference [SMD] = -0.49; 95% confidence interval [CI], -0.77 to -0.22; P &lt; 0.001) and depression (SMD = -0.37; 95% CI, -0.55 to -0.18; P &lt; 0.001) among caregivers, particularly in developing countries. However, no improvements in the anxiety (SMD = 0.00; 95% CI, -0.46 to 0.46; P = 0.99) and depression (SMD = -0.14; 95% CI, -0.32 to 0.04; P = 0.14) of children were observed.

CONCLUSIONS: Significant evidence exists regarding the positive effects of caregiver engagement interventions on caregivers&#039; anxiety and depression. Further recommendations for future research should focus on engagement interventions that reduce the anxiety and depression for children with chronic conditions.

IMPLICATIONS: Clinicians should concentrate on the mental health of chronically ill children and their caregivers and extend caregiver engagement therapies to improve anxiety and depression resulting from managing the disease. Copyright &copy; 2023 Elsevier Inc. All rights reserved.
AU  - Sheng,
AU  - N.
AU  - Ouyang,
AU  - N.
AU  - Zhou,
AU  - P.
AU  - Ge,
AU  - B.
AU  - Cheng,
AU  - F.
AU  - Lv,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.pedn.2023.04.015
L1  - internal-pdf://0186813425/1-s2.0-S0882596323001045-main.cleaned.pdf
PY  - 2023
T2  - Journal of pediatric nursing
TI  - Caregiver engagement interventions on reducing the anxiety and depression of children with chronic health conditions and their caregivers: A meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37164784
UR  - https://www.sciencedirect.com/science/article/pii/S0882596323001045?via%3Dihub
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Lithium is one of the most consistently effective treatment for mood disorders. However, patients may show a high level of heterogeneity in treatment response across the lifespan. In particular, the benefits of lithium use may vary in special clinical conditions. The aim of this study was to test this hypothesis by conducting an umbrella review on the efficacy and safety of lithium in childhood and adolescence, peripartum and old age. 

**METHODS**
We applied the Preferred Reporting Items for Systematic Reviews and Meta-analyses criteria (PRISMA) to identify systematic reviews/meta-analyses on the efficacy and/or safety of lithium in mood disorders in special clinical conditions: (i) childhood and adolescence; (ii) peripartum (pregnancy, postpartum and lactation); (iii) old age. The Risk of Bias Assessment Tool for Systematic Reviews (ROBIS) tool was used to assess the risk of bias. Overlap in primary studies across systematic reviews was calculated through the Corrected Covered Area (CCA). 

**RESULTS**
We included 20 independent studies, for a total of 8209 individuals treated with lithium. Regarding paediatric age, efficacy and safety results suggested that lithium may be superior to placebo in bipolar disorders (BD) and not associated with serious adverse events. Nevertheless, primary available data are very limited. Efficacy in paediatric major depressive disorder (MDD) is not clear. During peripartum, lithium use was superior to non-lithium in preventing mood episodes and it was associated with low risk of congenital anomalies and with normal child neurodevelopment. Regarding old age, limited evidence supported lithium as an effective treatment in BD and resistant MDD; low doses should be used in this population. Systematic reviews on paediatric age showed the lowest risk of bias (80% of the studies at low risk). The CCA range of included studies was 13-47%. 

**CONCLUSIONS**
This umbrella review supports the use of lithium across the lifespan, including special clinical condition. Nevertheless, more studies with increased methodological homogeneity are needed.
AN  - 36781741
AU  - Janiri,
AU  - D.
AU  - Sampogna,
AU  - G.
AU  - Albert,
AU  - U.
AU  - Caraci,
AU  - F.
AU  - Martinotti,
AU  - G.
AU  - Serafini,
AU  - G.
AU  - Tortorella,
AU  - A.
AU  - Zuddas,
AU  - A.
AU  - Fiorillo,
AU  - A.
AU  - Sani,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s40345-023-00287-7
L1  - internal-pdf://0522305123/Janiri-2023-Lithium use in childhood and adole.pdf
PY  - 2023
SP  - 8
T2  - International Journal of Bipolar Disorders
TI  - Lithium use in childhood and adolescence, peripartum, and old age: an umbrella review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36781741
UR  - https://journalbipolardisorders.springeropen.com/counter/pdf/10.1186/s40345-023-00287-7.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Background:** 
This systematic review and meta-analysis aimed to explore whether early interventions can reduce affective symptoms and have long-term benefits among individuals at risk of bipolar disorder (BD). 

**Methods:** 
The PubMed, Embase, and Web of Science databases were searched. The primary outcome was continuous symptom scores before and after treatment. Random effects meta-analyses were conducted for each outcome arm studied and pooled mean difference estimates were calculated. 

**Results:**
 The search identified 10 controlled studies involving 425 participants and 6 single-arm studies involving 90 participants. For controlled trials, meta-analysis showed that the interventions led to greater reduction in clinical global score than placebo (standardized mean differences (SMD) = -0.96, 95 % CI:-1.32, -0.60), and supported a long-term longitudinal effect for pharmacotherapy (SMD = -0.42, 95 % CI: -0.79, -0.05). For single-arm trials, both pharmacotherapy and psychotherapy showed efficacy for depressive symptoms, while pharmacotherapy only showed efficacy for hypomania symptoms (effect size (ES) = -9.16, 95 % CI:-11.29, -7.04). Discontinuation of pharmacotherapy due to adverse effects did not show a difference. Limitations: The primary limitations are the small number of RCTs and the influence of medication dosage. 

**Conclusions:**
Based on the limited available data, early interventions show efficacy for individuals at risk of BD. Psychological therapy might be more beneficial for depressive symptoms and have long-term benefits for hypomania. Pharmacotherapy may be appropriate in situations of severe hypomanic symptoms and the poor functioning. Large, well-designed, double-blind -controlled trials are needed to make solid conclusions about the efficacy of early interventions.
AN  - WOS:001052990100001
AU  - Fang,
AU  - M.
AU  - Fan,
AU  - Z.
AU  - L.
AU  - Liu,
AU  - S.
AU  - S.
AU  - Feng,
AU  - S.
AU  - T.
AU  - Zhu,
AU  - H.
AU  - Yin,
AU  - D.
AU  - Q.
AU  - Jia,
AU  - H.
AU  - X.
AU  - Wang,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.jad.2023.07.021
L1  - internal-pdf://3006395337/Fang_2023.pdf
PY  - 2023
SP  - 53-63
T2  - Journal of Affective Disorders
TI  - Preventive interventions for individuals at risk of developing bipolar disorder: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001052990100001
UR  - https://www.sciencedirect.com/science/article/pii/S016503272300856X?via%3Dihub
VL  - 340
ER  -
TY  - JOUR
AB  - **Background**
Evidence-based psychotherapies available to treat patients with bipolar disorders (BD) are limited. Dialectical behavior therapy (DBT) may target several common symptoms of BD. We conducted a systematic review on the efficacy of DBT for mood symptoms in patients with BD. The systematic search used key words related to DBT and BD in Medline, Embase, PsycInfo, CINAHL, and Cochrane Library databases from 1980 to April 1st, 2022. We included studies that enrolled patients with a BD I or II diagnosis (DSM or ICD), age 12 and older who received a DBT-based intervention. Studies reviewed were clinical trials including observational studies that reported at least one outcome related to BD mood symptoms or severity. We did not exclude based upon psychiatric or physical co-morbidity.

**Results**
We screened 848 abstracts and reviewed 28 full texts; 10 publications with 11 studies met our pre-determined eligibility criteria. All but one were feasibility pilot studies and most included participants in all mood states except for mania. The studies provided preliminary evidence suggesting these interventions may be effective for improving several core symptoms of BD. Overall, all the studies consistently supported that DBT-based interventions are feasible and acceptable for patients with BD.

**Conclusion**
DBT may be an effective treatment for BD; however, the confidence in this conclusion is limited by the small sample sizes, heterogeneity, and high risk of bias in all published trials. Larger well-designed RCTs are now required to establish the effectiveness of DBT in BD.
AN  - WOS:000924669100001
AU  - Jones,
AU  - B.
AU  - D.
AU  - M.
AU  - Umer,
AU  - M.
AU  - Kittur,
AU  - M.
AU  - E.
AU  - Finkelstein,
AU  - O.
AU  - Xue,
AU  - S.
AU  - Q.
AU  - Dimick,
AU  - M.
AU  - K.
AU  - Ortiz,
AU  - A.
AU  - Goldstein,
AU  - B.
AU  - I.
AU  - Mulsant,
AU  - B.
AU  - H.
AU  - Husain,
AU  - M.
AU  - I.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1186/s40345-023-00288-6
L1  - internal-pdf://2168894447/Jones-2023-A systematic review on the effectiv.pdf
PY  - 2023
SP  - 11
T2  - International Journal of Bipolar Disorders
TI  - A systematic review on the effectiveness of dialectical behavior therapy for improving mood symptoms in bipolar disorders
UR  - &lt;Go to ISI&gt;://WOS:000924669100001
UR  - https://journalbipolardisorders.springeropen.com/counter/pdf/10.1186/s40345-023-00288-6.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Background:** 
Therapeutic efficacies of probiotics in improving neurocognitive functions in infants and young children remained unclear. This meta-analysis focused on different cognitive outcomes in this population. 

**Methods:** 
Major databases were searched electronically from inception to October 2023 to identify randomized controlled trials (RCTs) that investigated the therapeutic efficacy of probiotics in enhancing cognitive functions assessed by standardized tasks. The overall effect size was calculated as standardized mean difference (SMD) based on a random effects model. 

**Results:** 
Nine RCTs with 3,026 participants were identified. Both our primary and secondary results demonstrated no significant difference in neurocognitive outcomes between infants/children treated with probiotics and those receiving placebos. However, our subgroup analysis of studies that offered a probiotics treatment course of over six months demonstrated a significantly better neurocognitive outcome than placebos (SMD = 0.21, p = 0.03, two studies with 451 participants), but this finding was based on only two RCTs. 

**Conclusion:** 
Despite lack of significant therapeutic effects of probiotics on neurocognitive outcomes, our finding of a positive impact of probiotics on neurocognitive development in those undergoing treatment for over six months may provide an important direction for further investigations into the enhancement of therapeutic effects of probiotics on neurocognitive development in infants and young children. Systematic review registration: PROSPERO CRD42023463412.
AN  - 38115853
AU  - Lin,
AU  - F.
AU  - L.
AU  - Chen,
AU  - C.
AU  - M.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Tzang,
AU  - R.
AU  - F.
AU  - Chiu,
AU  - H.
AU  - J.
AU  - Wang,
AU  - M.
AU  - Y.
AU  - Cheng,
AU  - Y.
AU  - C.
AU  - Hung,
AU  - K.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpubh.2023.1323511
L1  - internal-pdf://3387766333/Lin-2023-Effects of probiotics on neurocogniti.pdf
PY  - 2023
SP  - 1323511
T2  - Frontiers in Public Health
TI  - Effects of probiotics on neurocognitive outcomes in infants and young children: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38115853
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10728653/pdf/fpubh-11-1323511.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Background**
Despite improvements in medical care, the quality of life of adults and adolescents with congenital heart disease remains strongly affected by their condition, often leading to depression. Psychotherapy, cognitive behavioural therapy, and other talking therapies may be effective in treating depression in both adults and young adults with congenital heart disease. The aim of this review was to assess the effects of treatments, such as psychotherapy, cognitive behavioural therapies, and talking therapies for treating depression in this population.

**Objectives**
To evaluate the effects (both harms and benefits) of psychological interventions for reducing symptoms of depression in adolescents (aged 10 to 17 years) and adults with congenital heart disease. Psychological interventions include cognitive behavioural therapy, psychotherapy, or &#039;talking/counselling&#039; therapy for depression.

**Search methods**
We updated searches from the 2013 Cochrane Review by searching CENTRAL, four other databases, and Conference Proceedings Citation Index to 7 March 2023, and two clinical trial registers to February 2021. We applied no language restrictions.

**Selection criteria**
Randomised controlled trials (RCTs) comparing psychological interventions to no intervention in the congenital heart disease population, aged 10 years and older, with depression.

**Data collection and analysis**
Two review authors independently screened titles and abstracts, and independently assessed full‐text reports for inclusion. Further information was sought from the authors if needed. Data were extracted in duplicate. We used standard Cochrane methods. Our primary outcome was a change in depression. Our secondary outcomes were: acceptability of treatment, quality of life, hospital re‐admission, non‐fatal cardiovascular events, cardiovascular behavioural risk factor, health economics, cardiovascular mortality, all‐cause mortality. We used GRADE to assess the certainty of evidence for our primary outcome only.

**Main results**
We identified three new RCTs (480 participants). Participants were adults with congenital heart disease. Included studies varied in intervention length (90 minutes to 3 months) and follow‐up (3 to 12 months), with depression assessed post‐intervention and at follow‐up. Risk of bias assessment identified an overall low risk of bias for the main outcome of depression.Psychological interventions (talking/counselling therapy) may reduce depression more than usual care at both three‐month (mean difference (MD) ‐1.07, 95% confidence interval (CI) ‐1.84 to ‐0.30; P = 0.006; I2 = 0%; 2 RCTs, 156 participants; low‐certainty evidence), and 12‐month follow‐up (MD ‐1.02, 95% CI ‐1.92 to ‐0.13; P = 0.02; I2 = 0%; 2 RCTs, 287 participants; low‐certainty evidence).There was insufficient evidence to draw conclusions about the impact of psychological interventions on quality of life.None of the included studies reported on our other outcomes of interest.Due to the low number of studies included, we did not undertake any subgroup analyses. One study awaits classification.

**Authors&#039; conclusions**
Psychological interventions may reduce depression in adults with congenital heart disease compared to usual care. However, the certainty of the evidence is low.Further research is needed to establish the role of psychological interventions in this population, defining the optimal duration, method of administration, and number of sessions required to obtain the greatest benefit.
AU  - Leo,
AU  - D.
AU  - G.
AU  - Islam,
AU  - U.
AU  - Lotto,
AU  - R.
AU  - R.
AU  - Lotto,
AU  - A.
AU  - Lane,
AU  - D.
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD004372.pub3
L1  - internal-pdf://2850364660/Leo_et_al-2023-Cochrane_Database_of_Systematic.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological interventions for depression in adolescent and adult congenital heart disease
ER  -
TY  - JOUR
AB  - -
AN  - 36788670
AU  - Chiu,
AU  - H.
AU  - J.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Wang,
AU  - M.
AU  - Y.
AU  - Tzang,
AU  - R.
AU  - F.
AU  - Lin,
AU  - F.
AU  - L.
AU  - Cheng,
AU  - Y.
AU  - C.
AU  - Chung,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/j.eurpsy.2023.11
L1  - internal-pdf://0142193745/Chiu-2023-Efficacy and tolerability of psychos.pdf
PY  - 2023
SP  - 1-36
T2  - European Psychiatry: the Journal of the Association of European Psychiatrists
TI  - Efficacy and tolerability of psychostimulants for symptoms of ADHD in preschool children: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36788670
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/5907357DEDA7A81474D0976E8D139829/S0924933823000111a.pdf/div-class-title-efficacy-and-tolerability-of-psychostimulants-for-symptoms-of-attention-deficit-hyperactivity-disorder-in-preschool-children-a-systematic-review-and-meta-analysis-div.pdf
ER  -
TY  - JOUR
AB  - **Huvudbudskap**
Forskning visar att det finns insatser som involverar socialtj&auml;nst eller motsvarande som kan minska skjutvapenvåld, medlemskap i g&auml;ng och fortsatt kriminalitet bland unga personer.

**Slutsatser**
Efter att ha gått igenom den samlade vetenskapliga litteraturen har SBU dragit f&ouml;ljande slutsatser:

- F&auml;rdighetstr&auml;ning i skolan f&ouml;r elever på mellanstadiet (t.ex. konfliktl&ouml;sning) kan f&ouml;rebygga medlemskap i g&auml;ng och b&auml;rande av vapen.
- Insatser av typen fokuserad avskr&auml;ckning bland g&auml;ngkriminella minskar skjutvapenvåld med en fj&auml;rdedel, &ouml;ver en tid av i genomsnitt cirka tre år.
- Psykosociala insatser till g&auml;ngkriminella under frivård (t.ex. missbruksbehandling, st&ouml;d att s&ouml;ka arbete) kan minska fortsatt kriminalitet med knappt h&auml;lften upp till ett år efter avslutad insats.
Insatser mot &ouml;ppna drogmarknader i form av fokuserad avskr&auml;ckning kan minska narkotikabrottslighet med cirka en tredjedel, &ouml;ver en tid av i genomsnitt ett och ett halvt år.
- Insatser med os&auml;ker effektivitet eller os&auml;kra risker i form av stigmatisering och urholkat f&ouml;rtroende f&ouml;r viktiga samh&auml;llsfunktioner beh&ouml;ver utv&auml;rderas.


**Hur kan de viktigaste resultaten f&ouml;rstås?**
N&auml;stan alla studier &auml;r genomf&ouml;rda i USA. Det kan påverka resultatens relevans i Sverige. Det enda s&auml;kra s&auml;ttet att avg&ouml;ra om insatserna fungerar &auml;ven h&auml;r &auml;r genom att låta inf&ouml;ra och utv&auml;rdera insatserna i Sverige. I rapporten redovisas tre typer av insatser f&ouml;r att motverka g&auml;ngrelaterad kriminalitet. Universella insatser ges brett till många personer, till exempel till alla elever vid en skola. Selektiva insatser erbjuds personer med en f&ouml;rh&ouml;jd risk f&ouml;r g&auml;ngrelaterad kriminalitet. Indikerade insatser &auml;r inriktade mot g&auml;ngkriminella personer. Det kan handla om kriminalvård, insatser mot &ouml;ppna drogmarknader, och fokuserad avskr&auml;ckning. Insatserna kan vara frivilliga eller ske med tvång.

Resultaten tyder på att de indikerade insatserna &auml;r lika i flera avseenden. Framf&ouml;r allt f&ouml;rekommer samverkan mellan organisationer. Totalt f&ouml;rekommer tio olika delar, så kallade komponenter, som i varierande omfattning utg&ouml;r de indikerade insatserna. Den vanligaste komponenten &auml;r psykosocialt st&ouml;d från socialtj&auml;nst, som f&ouml;rekom i alla utom en insats. Andra vanliga komponenter &auml;r tydliga f&ouml;rv&auml;ntningar på g&auml;ngmedlemmar och tydliga sanktioner. Underlaget &auml;r f&ouml;r litet f&ouml;r mer riktade analyser om några komponenter &auml;r viktigare &auml;n andra.

**Vad handlar rapporten om?**
Det prim&auml;ra syftet &auml;r att utv&auml;rdera psykosociala insatser som ska motverka barns och ungas medlemskap i g&auml;ng, attityder till g&auml;ng och g&auml;ngrelaterad kriminalitet. Insatserna kan ges av socialtj&auml;nst eller andra relevanta akt&ouml;rer (t.ex. kriminalvård, skola, polis, civilsamh&auml;lle). Rapporten belyser också etiska aspekter som kan vara aktuella n&auml;r insatserna anv&auml;nds.

Det finns insatser d&auml;r det inte har gått att vetenskapligt bed&ouml;ma effekterna. Det g&auml;ller insatser som enbart ges på fångvårdsanstalt, familjebaserade insatser f&ouml;r antisociala tonåringar, medling, och insatser mot &ouml;ppna drogmarknader f&ouml;r att minska skjutvapenvåld.

**Vilka studier ligger till grund f&ouml;r resultaten?**
Resultatet baseras på 43 studier om psykosociala insatser till barn och unga vuxna under 30 år. Studierna har publicerats mellan år 2001 och april 2023 i vetenskapliga tidskrifter. Endast studier med en j&auml;mf&ouml;relsegrupp i form av standardbehandling har inkluderats.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /sv/publikationer/SBU-utvarderar/psykosociala-insatser-for-att-forebygga-och-minska-gangkriminalitet-bland-barn-och-unga-vuxna/
L1  - internal-pdf://2909739874/psykosociala-insatser-for-att-forebygga-och-mi.pdf
PY  - 2023
T2  - Statens beredning f&ouml;r medicinsk och social utv&auml;rdering (SBU)
TI  - Psykosociala insatser f&ouml;r att f&ouml;rebygga och minska g&auml;ngkriminalitet bland barn och unga vuxna
ER  -
TY  - JOUR
AB  - **Background** 
Children with callous-unemotional (CU) traits are at high lifetime risk of antisocial behavior. It is unknown if treatments for disruptive behavior disorders are as effective for children with CU traits (DBD+CU) as those without (DBD-only), nor if treatments directly reduce CU traits. Separate multilevel meta-analyses were conducted to compare treatment effects on DBD symptoms for DBD+CU versus DBD-only children and evaluate direct treatment-related reductions in CU traits, as well as to examine moderating factors for both questions.

**Methods** 
We systematically searched PsycINFO, PubMed, Cochran Library (Trials), EMBASE, MEDLINE, APA PsycNet, Scopus, and Web of Science. Eligible studies were randomized controlled trials, controlled trials, and uncontrolled studies evaluating child-focused, parenting-focused, pharmacological, family-focused, or multimodal treatments. 

**Results** 
Sixty studies with 9,405 participants were included (Mage = 10.04, SDage = 3.89 years, 25.09% female, 44.10% racial/ethnic minority). First, treatment was associated with similar reductions in DBD symptoms for DBD+CU (SMD = 1.08, 95% CI = 0.45, 1.72) and DBD-only (SMD = 1.01, 95% CI = 0.38, 1.64). However, DBD+CU started (SMD = 1.18, 95% CI = 0.57, 1.80) and ended (SMD = 0.73, p &lt; .001; 95% CI = 0.43, 1.04) treatment with more DBD symptoms. Second, although there was no overall direct effect of treatment on CU traits (SMD = .09, 95% CI = -0.02, 0.20), there were moderating factors. Significant treatment-related reductions in CU traits were found for studies testing parenting-focused components (SMD = 0.21, 95% CI = 0.06, 0.35), using parent-reported measures (SMD = 0.16, 95% CI = 0.04, 0.28), rated as higher quality (SMD = 0.26, 95% CI = 0.13, 0.39), conducted outside the United States (SMD = 0.19, 95% CI = 0.05, 0.32), and with less than half the sample from a racial/ethnic minority group (SMD = 0.15, 95% CI = 0.002, 0.30). 

**Conclusions** 
DBD+CU children improve with treatment, but their greater DBD symptom severity requires specialized treatment modules that could be implemented alongside parenting programs. Conclusions are tempered by heterogeneity across studies and scant evidence from randomized controlled trials. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-52464-001
AU  - Perlstein,
AU  - S.
AU  - Fair,
AU  - M.
AU  - Hong,
AU  - E.
AU  - Waller,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13774
L1  - internal-pdf://2520041148/Perlstein-2023-Treatment of childhood disrupti.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Journal of Child Psychology and Psychiatry
TI  - Treatment of childhood disruptive behavior disorders and callous-unemotional traits: A systematic review and two multilevel meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-52464-001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.13774?download=true
ER  -
TY  - JOUR
AB  - Sand therapy is a group of expressive arts interventions that is implemented with a variety of age groups that present to therapy with any number of chief complaints. In this study, we sought to establish an overall effect size for sand therapy, its efficacy with a variety of presenting problems, and the impact moderator variables may have had on effect size. For this meta-analysis, 36 studies were included, which yielded a Hedges&#039; g of 1.165. Additionally, meta-analyses were conducted on several different presenting problems including anxiety (k = 7, g = 1.425), anger (k = 5, g = .760), depression (k = 7, g = 1.071), parent-child relationship issues (k = 5, g = 3.932), and self-esteem (k = 6, g = 1.588). The impact of moderator analyses was conducted which indicated that sand therapy was as effective in group formats (k = 11, g = 1.073) as it was in individual settings (k = 7, g = 1.285). Additionally, age groups were analyzed, which indicated that sand therapy had high effect sizes that were roughly the same for adults (k = 14, g = 1.414), adolescents (k = 8, g = 1.035), and children (k = 14, g = 1.112). We discuss clinical implications for the use of sand therapy and further research suggestions. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AD  - Holliman, Ryan: holliman@tarleton.edu; Foster, Ryan D.: rdfoster@tarleton.eduHolliman, Ryan: Department of Counseling, Tarleton State University, 10850 Texan Rider Drive, Fort Worth, TX, US, 76036, holliman@tarleton.eduHolliman, Ryan: Department of Counseling, Tarleton State University, Fort Worth, TX, USFoster, Ryan D.: Department of Counseling, Tarleton State University, Fort Worth, TX, US
AN  - 2023-96572-007
AU  - Holliman,
AU  - R.
AU  - Foster,
AU  - R.
AU  - D.
DA  - May
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/23727810.2023.2232142
DP  - Ovid Technologies
KW  - sandplay
KW  - sandtray
KW  - expressive arts
KW  - meta-analysis
KW  - *Arts
KW  - *Developmental Stages
KW  - *Expressive Psychotherapy
KW  - *Group Psychotherapy
KW  - *Play Therapy
KW  - Psychotherapy &amp; Psychotherapeutic Counseling [3310]
KW  - Human
L1  - internal-pdf://0810898525/Holliman-2023-The way we play in the sand_ A m.pdf
LA  - English
M3  - Meta Analysis
N1  - DP - May 2023
PY  - 2023
SP  - 205-221
T2  - Journal of Child and Adolescent Counseling
TI  - The way we play in the sand: A meta-analytic investigation of sand therapy, its formats, and presenting problems
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2023-96572-007
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F23727810.2023.2232142&amp;issn=2372-7810&amp;isbn=&amp;volume=9&amp;issue=2&amp;spage=205&amp;pages=205-221&amp;date=2023&amp;title=Journal+of+Child+and+Adolescent+Counseling&amp;atitle=The+way+we+play+in+the+sand%3A+A+meta-analytic+investigation+of+sand+therapy%2C+its+formats%2C+and+presenting+problems.&amp;aulast=Holliman&amp;pid=%3Cauthor%3EHolliman%2C+Ryan%3C%2Fauthor%3E%3CAN%3E2023-96572-007%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/pdf/10.1080/23727810.2023.2232142
VL  - 9
ER  -
TY  - JOUR
AB  - **Background:** 
Suicidal thoughts and behaviors (STBs) in young people is a major public health problem, which is on the rise globally. 

**Aims:** 
We applied the first network meta-analyses to examine the effectiveness of existing intervention types and contents to reduce STBs and improve suicide prevention competencies in educational settings. 

**Method:** 
We searched Medline, PsycInfo, and CENTRAL until April 2021. Quantitative studies focused on young people aged between 12 and 25 years which evaluated interventions at educational settings and contained comparator groups were included. 

**Results:** 
Overall, we identified 49 studies comprising 42,039 participants. Regarding the type of intervention, universal interventions (OR = 1.85, 95% confidence interval [CI] [1.43&ndash;2.38]) were associated with almost two-fold reductions in the odds of STBs. Selective (standardized mean difference [SMD] = 0.51, 95% CI [0.32&ndash;0.70]) and universal interventions (SMD = 0.40, 0.26&ndash;0.54) were moderately effective in increasing suicide prevention competencies. Regarding the content of the intervention, education/awareness programs (OR = 1.59, 95% CI [1.23&ndash;2.04]) and psychotherapy programs (OR = 2.22, [1.25&ndash;3.33]) were associated with 1.5- and two-fold reductions in the odds of STBs. Gatekeeper universal interventions (SMD = 1.04, 95% CI [0.73&ndash;1.34]) and gatekeeper selective interventions (SMD = 0.52, [0.26&ndash;0.77]) were strong-to-moderately more effective in increasing suicide prevention competencies when compared to no-treatment. Education/awareness interventions were also modestly effective (SMD = 0.28, 95% CI [0.12&ndash;0.44]). The quality of 81% of the included studies was low. 

**Conclusions:** 
Important policy actions should be taken with a focus on offering universal mental health/suicide awareness training programs and/or selective treatments to reduce STBs and improve suicide prevention competencies in educational settings.
AN  - 2024-38968-001
AU  - Kiran,
AU  - T.
AU  - Angelakis,
AU  - I.
AU  - Panagioti,
AU  - M.
AU  - Irshad,
AU  - S.
AU  - Sattar,
AU  - R.
AU  - Hidayatullah,
AU  - S.
AU  - Tyler,
AU  - N.
AU  - Tofique,
AU  - S.
AU  - Bukhsh,
AU  - A.
AU  - Eylem-van
AU  - Bergeijk,
AU  - O.
AU  - Ozen-Dursun,
AU  - B.
AU  - Husain,
AU  - N.
AU  - Chaudhry,
AU  - N.
AU  - Hodkinson,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/cps0000179
L1  - internal-pdf://2335539279/2024-38968-001.cleaned.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Clinical Psychology: Science and Practice
TI  - Controlled interventions to improve suicide prevention in educational settings: A systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2024-38968-001
ER  -
TY  - JOUR
AB  - **BACKGROUND:**

Antipsychotic medications are increasingly used for difficult-to-treat depression in young people. However, the evidence-base for this is unclear. Our aim was to assess the evidence for the efficacy of atypical antipsychotics in treating unipolar and bipolar depression in adolescents and young adults. 

**METHOD:**

We conducted a comprehensive systematic review and meta-analysis of randomized-control-trial studies (RCTs) of antipsychotic medications for 10- to 25-year-olds with unipolar and bipolar depression. The primary outcome of interest was change in depressive symptoms from baseline to trial endpoint. 

**RESULTS:**

No studies were identified that evaluated the use of antipsychotics in the treatment of unipolar depression. However, we identified four studies, of quetiapine, lurasidone and olanzapine/fluoxetine combination, comprising a total of 866 randomized patients, that evaluated treatment of bipolar depression. All studies used the Children&#039;s Depression Rating Scale-Revised (CDRS-R). Our meta-analysis revealed the weighted mean difference (WMD) was -4.58 (95 % CI, -6.59 to -2.57) between antipsychotic and placebo-treated groups. Response and remission rates were also significantly in favor of antipsychotic treatment. 

**LIMITATIONS:**

There were few studies, several did not address risk-of-bias domains and there was a lack of non-industry sponsored studies. CONCLUSION: There is an absence of evidence for the use of antipsychotic medications in treatment of youth unipolar depression, and no recommendations can be made. There is some evidence for the efficacy of antipsychotics, specifically lurasidone and olanzapine/fluoxetine combination, in the treatment of young people with bipolar depression. However, this evidence is limited and more studies investigating the use of these medications in young people are needed.
AN  - 37467794
AU  - Garcia-Rodriguez,
AU  - L.
AU  - Burton,
AU  - D.
AU  - J.
AU  - Leonards,
AU  - C.
AU  - A.
AU  - Davey,
AU  - C.
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jad.2023.07.082
L1  - internal-pdf://1883247530/Garcia_2023.pdf
PY  - 2023
SP  - 633-639
T2  - Journal of Affective Disorders
TI  - Effectiveness of atypical antipsychotics for unipolar and bipolar depression in adolescents and young adults: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37467794
UR  - https://www.sciencedirect.com/science/article/pii/S0165032723009357?via%3Dihub
VL  - 339
ER  -
TY  - JOUR
AB  - TRIALS: The study aimed to investigate the effect of virtual reality interventions on relieving pain and anxiety in children and adolescents receiving cancer treatment. A search that involved Cochrane Library (comprising Cochrane Central Register of Controlled Trials (CENTRAL)), PubMed, ProQuest, MEDLINE, Web of Sciences, Science Direct, and Scopus electronic databases covering the records from January 1, 2000 up to May, 2023 was conducted to determine randomized controlled trials that could be included in our study. The results of the search were limited to &quot;anxiety and pain, adolescents, children, virtual reality, cancer.&quot; Of the 160 articles that were reached during the search, seven were found eligible based on inclusion criteria. Hedges&#039; g effect size was calculated for each article. Random effects model was used to test effect sizes and moderator variables. The registration number of this meta-analysis on PROSPERO is CRD42022304737. The outcomes were pain and anxiety. Compared with standard care, virtual reality had a medium and significant effect on anxiety (g = 0.60, 95% CI: [- 1.05 - 0.15]) and pain (g = - 0.667, 95% CI: [- 1.08- -0.24]). In addition, age has been identified as an important moderator in the use of virtual reality in pain management. This meta-analysis shows that virtual reality applications are effective interventions for reducing pain and anxiety in the field of pediatric oncology. However, it is necessary to carry out randomized controlled trials that have large samples for evidence-based virtual reality applications in pediatric oncology.
AD  - Ozturk, Cigdem Sari. Gazi University, Nursing Faculty, Pediatric Nursing Department, Ankara, Turkey. cigdemsari@gazi.edu.tr.Toruner, Ebru Kilicarslan. Gazi University, Nursing Faculty, Pediatric Nursing Department, Ankara, Turkey.
AN  - 37815610
AU  - Ozturk,
AU  - C.
AU  - S.
AU  - Toruner,
AU  - E.
AU  - K.
DA  - Oct 10
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10916-023-01995-4
DP  - Ovid Technologies
J2  - J Med Syst
L1  - internal-pdf://3260046068/Ozturk-2023-Effectiveness of Virtual Reality i.pdf
LA  - English
N1  - Ozturk, Cigdem SariToruner, Ebru Kilicarslan
PY  - 2023
SP  - 103
T2  - Journal of Medical Systems
TI  - Effectiveness of Virtual Reality in Anxiety and Pain Management in Children and Adolescents Receiving Cancer Treatment: A Systematic Review and Meta-analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=37815610
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37815610&amp;id=doi:10.1007%2Fs10916-023-01995-4&amp;issn=0148-5598&amp;isbn=&amp;volume=47&amp;issue=1&amp;spage=103&amp;pages=103&amp;date=2023&amp;title=Journal+of+Medical+Systems&amp;atitle=Effectiveness+of+Virtual+Reality+in+Anxiety+and+Pain+Management+in+Children+and+Adolescents+Receiving+Cancer+Treatment%3A+A+Systematic+Review+and+Meta-analysis+of+Randomized+Controlled+Trials.&amp;aulast=Ozturk&amp;pid=%3Cauthor%3EOzturk+CS%3C%2Fauthor%3E%3CAN%3E37815610%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s10916-023-01995-4.pdf
VL  - 47
ER  -
TY  - JOUR
AB  - We performed a systematic and meta-analytic review of biofeedback-based interventions on psychological outcomes among pediatric populations. The literature search for this study was conducted in eight databases, including PubMed, the Cochrane Library, Scopus, CINAHL, Embase (OVID), Web of Science, PsycINFO (all via Ovid SP), and Google Scholar. The methodological quality of the studies was assessed using the Critical Appraisal Checklists for experimental and quasi-experimental studies that was developed by the Joanna Briggs Institute. We analyzed the effects of biofeedback-based interventions on psychological outcomes in the pediatric population by following the Preferred Reporting System for Systematic Reviews and Meta-Analysis. This systematic review and meta-analysis included nine studies with a total sample size of 658 children. In this study, EEG, EMG, and heart rate variability biofeedback were utilized to treat psychological symptoms in children. All studies focused on anxiety, with only one studying depression. As a result, it was found that all types of biofeedback effectively reduced children&#039;s anxiety levels. It was recommended that biofeedback-based interventions should be used to reduce children&#039;s anxiety. Copyright &copy; 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
AN  - 37016184
AU  - Umac,
AU  - E.
AU  - H.
AU  - Semerci,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10484-023-09583-5
L1  - internal-pdf://0453602063/Umac-2023-Effect of Biofeedback-Based Interven.pdf
PY  - 2023
SP  - 04
T2  - Applied Psychophysiology &amp; Biofeedback
TI  - Effect of Biofeedback-Based Interventions on the Psychological Outcomes of Pediatric Populations: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37016184
UR  - https://link.springer.com/article/10.1007/s10484-023-09583-5
UR  - https://link.springer.com/content/pdf/10.1007/s10484-023-09583-5.pdf
VL  - 04
ER  -
TY  - JOUR
AB  - BACKGROUND: Executive function plays a crucial role in children&#039;s cognitive development, academic performance, as well as their physical and mental health. This study aims to assess the impact of exergaming on executive functions in pediatric populations.

METHODS: The criteria of inclusion were randomized controlled trials of exergaming intervention and evaluation of executive function in children aged 4-12 years. A meta-analysis was performed in databases of China National Knowledge Infrastructure (in Chinese), Wan Fang (in Chinese), Web of Science, Embase, and PubMed, from January 2010 to February 2023, following the PRISMA guidelines. Risk of bias was assessed by the Jadad scale, the Cochrane risk of bias assessment tool, funnel plot, and regression-based Egger test. The Review Manager 5.3 was used to analyze the included articles using a random-effects model, and the effects were calculated as standardized mean difference (SMD).

RESULTS: Eleven experimental studies with children (n = 508) were included. Exergaming was found to have a positive impact on children&#039;s cognitive flexibility (SMD = 0.34, 95%CI [0.17,0.52], P &lt; 0.01), inhibitory control (SMD = 0.57, 95%CI [0.31,0.83], P &lt; 0.01), and working memory (SMD = 0.26, 95%CI [0.02,0.51], P &lt; 0.05). The publication bias were observed.

CONCLUSIONS: Exergaming has the potential to improve executive functions in children. More studies with rigorous designs are warranted to explore the specific effects of exergaming intervention. This study was registered on the PROSPERO (CRD42023401526).
AD  - Chen, Jiaqi. Department of Preschool Education, Jiaxing University, Jiaxing, China.Zhou, Xiaojiao. Department of Preschool Education, Jiaxing University, Jiaxing, China.Zhou, Xiaojiao. Institute of Child Development, Jiaxing University, Jiaxing, China.Wu, Xiangting. Department of Preschool Education, Jiaxing University, Jiaxing, China.Gao, Zan. Department of Kinesiology, Recreation, and Sport Studies, The University of Tennessee, Knoxville, TN, USA.Ye, Sunyue. Department of Preschool Education, Jiaxing University, Jiaxing, China. syye@zjxu.edu.cn.Ye, Sunyue. Institute of Child Development, Jiaxing University, Jiaxing, China. syye@zjxu.edu.cn.
AN  - 37833741
AU  - Chen,
AU  - J.
AU  - Zhou,
AU  - X.
AU  - Wu,
AU  - X.
AU  - Gao,
AU  - Z.
AU  - Ye,
AU  - S.
DA  - Oct 13
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s13690-023-01195-z
DP  - Ovid Technologies
J2  - Arch
L1  - internal-pdf://4166537833/Chen-2023-Effects of exergaming on executive f.pdf
LA  - English
N1  - Chen, JiaqiZhou, XiaojiaoWu, XiangtingGao, ZanYe, Sunyue
PY  - 2023
SP  - 182
T2  - Archives of Public Health
TI  - Effects of exergaming on executive functions of children: a systematic review and meta-analysis from 2010 to 2023
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37833741
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37833741&amp;id=doi:10.1186%2Fs13690-023-01195-z&amp;issn=0778-7367&amp;isbn=&amp;volume=81&amp;issue=1&amp;spage=182&amp;pages=182&amp;date=2023&amp;title=Archives+of+Public+Health&amp;atitle=Effects+of+exergaming+on+executive+functions+of+children%3A+a+systematic+review+and+meta-analysis+from+2010+to+2023.&amp;aulast=Chen&amp;pid=%3Cauthor%3EChen+J%3C%2Fauthor%3E%3CAN%3E37833741%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://archpublichealth.biomedcentral.com/counter/pdf/10.1186/s13690-023-01195-z.pdf
VL  - 81
ER  -
TY  - JOUR
AB  - This systematic review and synthesis summarizes intervention research for Grade K-12 students with a reading difficulty and co-occurring inattention to identify (a) the relevant intervention literature base, (b) the student, study, and intervention characteristics of these studies, (c) the effects of these interventions on reading and behavior outcomes, and (d) the collateral impact of reading interventions and behavior interventions on behavior outcomes and reading outcomes, respectively. Our search process yielded 14 eligible studies. Findings suggest that word reading instruction is associated with improved word reading outcomes and self-monitoring and function-based interventions are associated with improved student behavior. No study measured a collateral effect for reading or behavior interventions. Future reading intervention research is needed to better understand how to improve the reading and behavior outcomes for Grade K-12 students with a reading difficulty and co-occurring inattention. A PRISMA-compliant abstract can be found at .
AN  - WOS:000980181900001
AU  - Roberts,
AU  - G.
AU  - J.
AU  - Lindstrom,
AU  - E.
AU  - R.
AU  - Jimenez,
AU  - Z.
AU  - Ghosh,
AU  - E.
AU  - Mehmedovic,
AU  - S.
AU  - McFadden,
AU  - K.
AU  - A.
AU  - Fallah,
AU  - M.
AU  - B.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1007/s10864-023-09517-5
L1  - internal-pdf://0133357920/Intervention Research for Students with Co-occ.pdf
PY  - 2023
SP  - 25
T2  - Journal of Behavioral Education
TI  - Intervention Research for Students with Co-occurring Reading Difficulties and Inattention: A Systematic Review of Single-Case Design Studies
UR  - &lt;Go to ISI&gt;://WOS:000980181900001
UR  - https://link.springer.com/article/10.1007/s10864-023-09517-5
ER  -
TY  - JOUR
AB  - Digital game-based training programs have recently been used to train the cognitive abilities of children with neurodevelopmental disorders (NDDs). However, the effects of training remain controversial. The present meta-analysis explored the effectiveness of digital game-based training in children with NDDs and examined the possible moderators of its effects. Twenty-nine studies with cognitive outcomes in 1535 children were included in the present meta-analysis. The results showed that digital game-based training could significantly enhance the core cognitive abilities of children with each type of NDDs and that training could be used remotely. Meanwhile, task content and game features of digital game-based interventions separately make unique and significant contributions to the training effects, suggesting that the combination of training content and game features could efficiently improve children&#039;s cognition. Although the present study revealed that the training benefits could be maintained over a period of time, more studies are needed to explore the retention effects of digital game-based training. The present study provides a comprehensive understanding of the training effects of digital game-based interventions and new insights for future cognitive training design and application.
AN  - 36603312
AU  - Ren,
AU  - X.
AU  - Wu,
AU  - Q.
AU  - Cui,
AU  - N.
AU  - Zhao,
AU  - J.
AU  - Bi,
AU  - H.
AU  - Y.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.ridd.2022.104418
L1  - internal-pdf://0461036834/1-s2.0-S0891422222002487-main.cleaned.pdf
PY  - 2023
SP  - 104418
T2  - Research in Developmental Disabilities
TI  - Effectiveness of digital game-based trainings in children with neurodevelopmental disorders: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36603312
VL  - 133
ER  -
TY  - JOUR
AB  - **Background**
Attention deficit hyperactivity disorder (ADHD) is a major problem in children and adolescents, characterised by age‐inappropriate levels of inattention, hyperactivity, and impulsivity, and is associated with long‐term social, academic, and mental health problems. The stimulant medications methylphenidate and amphetamine are the most frequently used treatments for ADHD, but these are not always effective and can be associated with side effects. Clinical and biochemical evidence suggests that deficiencies of polyunsaturated fatty acids (PUFA) could be related to ADHD. Research has shown that children and adolescents with ADHD have significantly lower plasma and blood concentrations of PUFA and, in particular, lower levels of omega‐3 PUFA. These findings suggest that PUFA supplementation may reduce the attention and behaviour problems associated with ADHD. This review is an update of a previously published Cochrane Review. Overall, there was little evidence that PUFA supplementation improved symptoms of ADHD in children and adolescents.

**Objectives**
To compare the efficacy of PUFA to other forms of treatment or placebo in treating the symptoms of ADHD in children and adolescents.

**Search methods**
We searched 13 databases and two trials registers up to October 2021. We also checked the reference lists of relevant studies and reviews for additional references.

**Selection criteria**
We included randomised and quasi‐randomised controlled trials that compared PUFA with placebo or PUFA plus alternative therapy (medication, behavioural therapy, or psychotherapy) with the same alternative therapy alone in children and adolescents (aged 18 years and under) diagnosed with ADHD.

**Data collection and analysis**
We used standard Cochrane methods. Our primary outcome was severity or improvement of ADHD symptoms. Our secondary outcomes were severity or incidence of behavioural problems; quality of life; severity or incidence of depressive symptoms; severity or incidence of anxiety symptoms; side effects; loss to follow‐up; and cost. We used GRADE to assess the certainty of evidence for each outcome.

**Main results**
We included 37 trials with more than 2374 participants, of which 24 trials were new to this update. Five trials (seven reports) used a cross‐over design, while the remaining 32 trials (52 reports) used a parallel design. Seven trials were conducted in Iran, four each in the USA and Israel, and two each in Australia, Canada, New Zealand, Sweden, and the UK. Single studies were conducted in Brazil, France, Germany, India, Italy, Japan, Mexico, the Netherlands, Singapore, Spain, Sri Lanka, and Taiwan. Of the 36 trials that compared a PUFA to placebo, 19 used an omega‐3 PUFA, six used a combined omega‐3/omega‐6 supplement, and two used an omega‐6 PUFA. The nine remaining trials were included in the comparison of PUFA to placebo, but also had the same co‐intervention in the PUFA and placebo groups. Of these, four trials compared a combination of omega‐3 PUFA plus methylphenidate to methylphenidate. One trial each compared omega‐3 PUFA plus atomoxetine to atomoxetine; omega‐3 PUFA plus physical training to physical training; and an omega‐3 or omega‐6 supplement plus methylphenidate to methylphenidate; and two trials compared omega‐3 PUFA plus dietary supplement to dietary supplement. Supplements were given for a period of between two weeks and six months.

Although we found low-certainty evidence that PUFA compared to placebo may improve ADHD symptoms in the medium term (risk ratio (RR) 1.95, 95% confidence interval (CI) 1.47 to 2.60; 3 studies, 191 participants), there was high-certainty evidence that PUFA had no effect on parent-rated total ADHD symptoms compared to placebo in the medium term (standardised mean difference (SMD) &minus;0.08, 95% CI &minus;0.24 to 0.07; 16 studies, 1166 participants). There was also high-certainty evidence that parent-rated inattention (medium-term: SMD &minus;0.01, 95% CI &minus;0.20 to 0.17; 12 studies, 960 participants) and hyperactivity/impulsivity (medium-term: SMD 0.09, 95% CI &minus;0.04 to 0.23; 10 studies, 869 participants) scores were no different compared to placebo.

There was moderate-certainty evidence that overall side effects likely did not differ between PUFA and placebo groups (RR 1.02, 95% CI 0.69 to 1.52; 8 studies, 591 participants). There was also moderate-certainty evidence that medium-term loss to follow-up was likely similar between groups (RR 1.03, 95% CI 0.77 to 1.37; 13 studies, 1121 participants).

**Authors&#039; conclusions**
Although we found low-certainty evidence that children and adolescents receiving PUFA may be more likely to improve compared to those receiving placebo, there was high-certainty evidence that PUFA had no effect on total parent-rated ADHD symptoms. There was also highcertainty evidence that inattention and hyperactivity/impulsivity did not differ between PUFA and placebo groups.

We found moderate-certainty evidence that overall side effects likely did not differ between PUFA and placebo groups. There was also moderate-certainty evidence that follow-up was similar between groups.

It is important that future research addresses the current weaknesses in this area, which include small sample sizes, variability of selection criteria, variability of the type and dosage of supplementation, and short follow-up times.
AU  - Gillies,
AU  - D.
AU  - Leach,
AU  - M.
AU  - J.
AU  - Perez
AU  - Algorta,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD007986.pub3
L1  - internal-pdf://2987136256/Gillies_et_al-2023-Cochrane_Database_of_System.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Polyunsaturated fatty acids (PUFA) for attention deficit hyperactivity disorder (ADHD) in children and adolescents
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Attachment refers to an infant&#039;s innate tendency to seek comfort from their caregiver. Research shows that attachment is important in promoting healthy social and emotional development. Many parenting interventions have been developed to improve attachment outcomes for children. However, numerous interventions used in routine practice have a limited evidence base, meaning that we cannot be sure if they are helpful or harmful. 

OBJECTIVES: 
This research aimed to conduct a large-scale survey to identify what interventions are being used in UK services to improve child attachment; conduct a systematic review to evaluate the evidence for parenting attachment interventions; and develop recommendations for future research and practice. 

DESIGN AND METHODS: 
We worked closely with our Expert Reference Group to plan a large-scale survey focused on relevant UK services. We then conducted two systematic reviews. One searched for all randomised controlled trial evidence for any attachment parenting intervention. The second searched for all research for the top 10 routinely used interventions identified from the survey. 

RESULTS: 
The survey collected 625 responses covering 734 UK services. The results identified the 10 most commonly used interventions. The responses showed a limited use of validated measures and a wide variety of definitions of attachment. For the first review, seven studies were included from 2516 identified records. These were combined with results from previous reviews conducted by the team. Meta-analyses showed that, overall, parenting interventions are effective in reducing disorganised attachment (pooled odds ratio 0.54, 95% confidence interval 0.39 to 0.77) and increasing secure attachment (pooled odds ratio 1.85, 95% confidence interval 1.36 to 2.52). The second review searched the literature for the top 10 routinely used interventions identified by the survey; 61 studies were included from 1198 identified records. The results showed that many of the most commonly used interventions in UK services have a weak evidence base and those with the strongest evidence base are not as widely used. 

CONCLUSIONS: 
There is a need for better links between research and practice to ensure that interventions offered to families are safe and effective. Possible reasons for the disparity include the cost and accessibility of training. There is also a need for improved understanding by professionals regarding the meaning of attachment. 

LIMITATIONS: Although the survey had good geographical spread, most respondents were based in England. For review 2 we were unable to access a large number of papers; however, we conducted extensive reference checking to account for this. 

FUTURE WORK: There is a need for robust research to test the efficacy of routinely used attachment interventions. Research could also explore why routinely used interventions are not consistently subject to thorough evaluation; how to embed dissemination, cost-effectiveness, fidelity and sustainability into research; and how to keep clinical practice up to date with research developments. 

STUDY REGISTRATION: This study is registered as PROSPERO CRD42019137362. FUNDING: This project was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 27, No. 2. See the NIHR Journals Library website for further project information.
AN  - 36722615
AU  - Wright,
AU  - B.
AU  - Fearon,
AU  - P.
AU  - Garside,
AU  - M.
AU  - Tsappis,
AU  - E.
AU  - Amoah,
AU  - E.
AU  - Glaser,
AU  - D.
AU  - Allgar,
AU  - V.
AU  - Minnis,
AU  - H.
AU  - Woolgar,
AU  - M.
AU  - Churchill,
AU  - R.
AU  - McMillan,
AU  - D.
AU  - Fonagy,
AU  - P.
AU  - O&#039;Sullivan,
AU  - A.
AU  - McHale,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3310/IVCN8847
L1  - internal-pdf://3998683300/Wright-2023-Routinely used interventions to im.pdf
PY  - 2023
SP  - 1-226
T2  - Health Technology Assessment (Winchester, England)
TI  - Routinely used interventions to improve attachment in infants and young children: a national survey and two systematic reviews
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36722615
UR  - https://njl-admin.nihr.ac.uk/document/download/2041946
VL  - 27
ER  -
TY  - JOUR
AB  - CONTEXT: Physical activity (PA) interventions improve well-being and positive mental health in children and adolescents, but the results of previous systematic reviews included participants with chronic medical conditions and did not accurately assess the multidimensional nature of health-related quality of life (HRQoL). 

OBJECTIVE: The aims of this meta-analysis were to (1) evaluate the effects of PA interventions on several domains of HRQoL in healthy &lt;18-year-olds and (2) examine the effectiveness of interventions on HRQoL according to whether they were successful in increasing PA, the type of intervention delivered, and the duration of the intervention. 

DATA SOURCES: PubMed (Medline), EMBASE, the Cochrane Library, SCIELO, SPORTDiscus, and PEDro databases were systematically searched from inception to September 30, 2022. 

STUDY SELECTION: Experimental studies that examined the effectiveness of PA interventions on HRQoL participants aged &lt;18 years. 

STUDY DESIGN: Systematic review with meta-analysis and meta-regression. 

LEVEL OF EVIDENCE: Level 1. 

METHODS: Random-effects models were used to calculate pooled effect size (ES) for total HRQoL score and its dimensions. Subgroup analyses were conducted to examine the effect of PA program characteristics. 

RESULTS: A total of 17 studies were included. Pooled ES (95% CI) estimations were as follows: 0.179 (0.045, 0.002) for total HRQoL score, 0.192 (0.077, 0.306) for physical well-being, 0.158 (0.080, 0.237) for psychological well-being, 0.118 (0.044, 0.192) for autonomy and parent relation, 0.135 (0.043, 0.227) for social support and peers, and 0.129 (-0.013, 0.270) for school environment. Subgroup analyses suggested there were no differences in the effectiveness of the interventions by category of PA increase or by type and duration of intervention. 

CONCLUSION: Exercise interventions are an effective strategy for improving overall HRQoL and its most significant domains in children and adolescents.
AN  - 37608692
AU  - Bermejo-Cantarero,
AU  - A.
AU  - Sanchez-Lopez,
AU  - M.
AU  - Alvarez-Bueno,
AU  - C.
AU  - Redondo-Tebar,
AU  - A.
AU  - Garcia-Hermoso,
AU  - A.
AU  - Martinez-Vizcaino,
AU  - V.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/19417381231190885
L1  - internal-pdf://1068970334/Bermejo_2023.pdf
PY  - 2023
SP  - 19417381231190885
T2  - Sports &amp; Health
TI  - Are Physical Activity Interventions Effective in Improving Health-Related Quality of Life in Children and Adolescents? A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37608692
UR  - https://journals.sagepub.com/doi/10.1177/19417381231190885
ER  -
TY  - JOUR
AB  - There are several meta-analyses of treatment effects for children and adolescents with attention deficit hyperactivity disorder (ADHD). The conclusions of these meta-analyses vary considerably. Our aim was to synthesize the latest evidence of the effectiveness of psychological, pharmacological treatment options and their combination in a systematic overview and meta-meta-analyses. A systematic literature search until July 2022 to identify meta-analyses investigating effects of treatments for children and adolescents with ADHD and ADHD symptom severity as primary outcome (parent and teacher rated) yielded 16 meta-analyses for quantitative analyses. Meta-meta-analyses of pre-post data showed significant effects for pharmacological treatment options for parent (SMD = 0.67, 95% CI 0.60 to 0.74) and teacher ADHD symptom ratings (SMD = 0.68, 95% CI 0.54 to 0.82) as well as for psychological interventions for parent (SMD = 0.42, 95% CI 0.33 to 0.51) and teacher rated symptoms (SMD = 0.25, 95% CI 0.12 to 0.38). We were unable to calculate effect sizes for combined treatments due to the lack of meta-analyses. Our analyses revealed that there is a lack of research on combined treatments and for therapy options for adolescents. Finally, future research efforts should adhere to scientific standards as this allows comparison of effects across meta-analyses. Copyright &copy; 2023. Published by Elsevier Ltd.
AN  - 37030086
AU  - Turk,
AU  - S.
AU  - Korfmacher,
AU  - A.
AU  - K.
AU  - Gerger,
AU  - H.
AU  - van
AU  - der
AU  - Oord,
AU  - S.
AU  - Christiansen,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.cpr.2023.102271
L1  - internal-pdf://3506134605/Turk_2023.pdf
PY  - 2023
SP  - 102271
T2  - Clinical Psychology Review
TI  - Interventions for ADHD in childhood and adolescence: A systematic umbrella review and meta-meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37030086
UR  - https://www.sciencedirect.com/science/article/pii/S0272735823000296?via%3Dihub
VL  - 102
ER  -
TY  - JOUR
AB  - Recently, especially after the 2020 COVID-19 pandemic, the shift towards technology-based non-face-to-face family prevention programmes to deal with problem behaviours has increased. Different systematic reviews and meta-analyses have explored the results of the virtual versions of the programmes. However, a global summary or systematized overview of the main conclusions and implications of the different reviews is needed to establish the scientific contributions of the new formats and to help the providers of the online programmes to know the components that work and to what extent. A lack of systematized information on the different delivery modes has also been detected. 

This study addresses these issues by systematically analysing existing reviews and meta-analyses, examining the reported outcomes and, when available, results related to delivery conditions and adherence variables. 

The analysis results suggest a reduction in children&#039;s problem behaviours and a consensus on the necessity of reporting on the parental stress variable. 

In conclusion, it highlights the need for more information on delivery conditions, given the structural change in how these programmes or interventions are provided, together with data on adherence and family variables (family relationships and interactions such as family communication and family resilience).
AN  - WOS:001091257600001
AU  - Valero,
AU  - M.
AU  - Quesada,
AU  - V.
AU  - Oliver,
AU  - J.
AU  - L.
AU  - Amer,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1111/cfs.13098
L1  - internal-pdf://3005686183/Child Family Social Work - 2023 - Valero - E.pdf
PY  - 2023
SP  - 15
T2  - Child &amp; Family Social Work
TI  - Efficacy of technology-based parenting programmes in reducing behaviour problems: An analysis of systematic reviews and meta-analyses
UR  - &lt;Go to ISI&gt;://WOS:001091257600001
ER  -
TY  - JOUR
AB  - BACKGROUND: Executive function is a core deficit in children with attention deficit hyperactivity disorder (ADHD). This study systematically reviewed the evidence for the effects of physical activity (PA) interventions on executive function in children and adolescents with ADHD and explored the moderating effects of key variables of PA on executive function. 

METHODS: Relevant literature in four electronic databases, Pubmed, Web of Science, Cochrane Library, and Embase, were systematically searched. Revman 5.4 was used for data analysis, and combined effect sizes, heterogeneity tests, subgroup analyses, and sensitivity analyses were calculated. Egger&#039;s test in Stata 15.0 was used for publication bias testing. 

RESULTS: A total of 24 articles with 914 participants were included. Meta-analysis showed that PA interventions improved inhibitory control (SMD = -0.50, 95%CI [-0.71, -0.29], P &lt; 0.00001), working memory (SMD = -0.50, 95%CI [-0.83, -0.16], P = 0.004) and cognitive flexibility in children and adolescents with ADHD (SMD = -0.45, 95%CI [-0.81, -0.09], P = 0.01). Subgroup analysis revealed a moderating effect of intervention intensity, motor skill type, sessions of PA, and weekly exercise volume on executive function. 

CONCLUSION: PA interventions had positive effects on improvements in core executive functions in children and adolescents with ADHD and were influenced by intervention intensity, type of motor skill, sessions of PA, and amount of exercise. This has practical implications for the formulation of PA interventions programs.
AN  - 37590250
AU  - Song,
AU  - Y.
AU  - Fan,
AU  - B.
AU  - Wang,
AU  - C.
AU  - Yu,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0289732
L1  - internal-pdf://3951733475/Song-2023-Meta-analysis of the effects of phys.pdf
PY  - 2023
SP  - e0289732
T2  - PLoS ONE [Electronic Resource]
TI  - Meta-analysis of the effects of physical activity on executive function in children and adolescents with attention deficit hyperactivity disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37590250
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0289732&amp;type=printable
VL  - 18
ER  -
TY  - JOUR
AB  - **OBJECTIVES:**

Whole-school interventions that promote student commitment to school are a promising modality to reduce health inequalities through school-level change; however, evidence for the effectiveness of these interventions in improving policy-relevant health outcomes, such as substance use and violence, has not been comprehensively synthesised. 

**STUDY DESIGN:**

This was a systematic review and meta-analysis.

**METHODS:**

We searched 20 databases and a range of other sources to identify randomised trials meeting our intervention definition and reporting substance use and violence outcomes. Extracted effect estimates were meta-analysed using robust variance estimation with random effects, separating effects &lt;1 year from baseline and effects at or more than 1 year from baseline. 

**RESULTS:**

We included 18 evaluations with varying risk of bias. Pooled effects suggested significant impacts on short-term (odds ratio [OR] = 0.85, 95% confidence interval [CI] 0.76, 0.96) and long-term (OR = 0.79, 95% CI 0.65, 0.98) violence perpetration, short-term (OR = 0.84, 95% CI 0.72, 0.98) and long-term (OR = 0.85, 95% CI 0.73, 0.99) violence victimisation, and short-term (OR = 0.83, 95% CI 0.70, 0.97) and long-term (OR = 0.79, 95% CI 0.62, 0.998) substance use outcomes, with effects relatively stable between short-term and long-term analyses. Stratifying substance use meta-analyses by type (e.g. smoking, alcohol) did not impact results. All meta-analyses had substantial heterogeneity. 

**CONCLUSION:**

Although diverse in content, interventions appear effective with respect to the review outcomes and as a form of universal prevention. Future research should consider contextual contingencies in intervention effectiveness, given considerable policy and practice interest in these interventions and the need to support schools in effective decision-making as to intervention choice.
AN  - 37480745
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Ponsford,
AU  - R.
AU  - Falconer,
AU  - J.
AU  - Bonell,
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.puhe.2023.06.021
L1  - internal-pdf://0614998889/Melendez_2023.pdf
PY  - 2023
SP  - 190-197
T2  - Public Health
TI  - Whole-school interventions promoting student commitment to school to prevent substance use and violence: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37480745
UR  - https://www.sciencedirect.com/science/article/pii/S003335062300210X?via%3Dihub
VL  - 221
ER  -
TY  - JOUR
AB  - The physical and psychological benefits of physical activity are well established. However, there is no consensus regarding the effects of physical activity on children&#039;s academic performance in general and in specific subjects. We conducted this systematic review and meta-analysis to identify forms of physical activity that are suitable for improving the physical activity levels and academic performance of children aged 12 years and under. The PubMed, Web of Science, Embase, and Cochrane Library databases were searched. Included studies had to meet the following criteria: randomized controlled trials examining the effect of physical activity interventions on children&#039;s academic performance. Stata 15.1 software was used to conduct the meta-analysis. A total of 16 studies were included, and the results showed that the &quot;physical activity + academic curriculum&quot; format had a positive effect on children&#039;s academic performance. Physical activity had a stronger effect on math performance than on reading and spelling performance (SMD = 0.75, 95% CI: 0.30,1.19, P &lt; 0.001). Conclusion: The impact of physical activity on children&#039;s academic performance varies based on the type of physical activity intervention, with &quot;physical activity + academic curriculum&quot; format having a better effect on academic performance. The effect of physical activity interventions on children&#039;s academic performance also varies by subject; the effect is strongest for math. Trial registration: Registration and protocol CRD42022363255. What is Known: * The physical and psychological benefits of physical activity are well established. * Previous meta-analyses have failed to demonstrate the impact of physical activity on the general and subject-specific academic performance of children aged 12 and under. What is New: * The PAAL form of physical activity has a better effect on the academic performance of children aged 12 and under. * The benefit of physical activity also varies by subject, with the greatest effect being observed for math. Copyright &copy; 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
AU  - Li,
AU  - D.
AU  - Wang,
AU  - D.
AU  - Zou,
AU  - J.
AU  - Li,
AU  - C.
AU  - Qian,
AU  - H.
AU  - Yan,
AU  - J.
AU  - He,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00431-023-05009-w
L1  - internal-pdf://4228873766/Li-2023-Effect of physical activity interventi.pdf
PY  - 2023
T2  - European journal of pediatrics
TI  - Effect of physical activity interventions on children&#039;s academic performance: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37227500
UR  - https://link.springer.com/article/10.1007/s00431-023-05009-w
UR  - https://link.springer.com/content/pdf/10.1007/s00431-023-05009-w.pdf
ER  -
TY  - JOUR
AB  - **Introduction:** 
Traditional Chinese medicine (TCM) is a type of alternative medicine that has been widely utilized in the prevention and treatment of neuropsychiatric diseases such as schizophrenia, ADHD, Alzheimer disease, and Tourette syndrome (TS) in many countries. However, the results regarding TCM&#039;s effectiveness and safety in treating TS are conflicting. Therefore, the goal of the present study is to analyze and summarize the available literature related to the efficacy of TCM in the treatment of tic disorders, especially TS. 

**Methods:** 
Relevant articles for the meta-analysis were searched using appropriate keywords from PubMed, MEDLINE, and CENTRAL databases. Event data for TCM for the treatment of TS in the control and intervention arms were determined from the randomized controlled trials, and diagnostic odds ratio (DOR) and risk of bias analysis were performed. Meta-analysis was performed using MedCalc software, and suitable parameters to assess heterogeneity were computed.

**Results:** 
Twelve randomized clinical trials with a total of 1,681 TS patients were included as per the inclusion criteria. The patients&#039; clinical symptoms were improved to a greater extent, and the pooled DOR of 1.311 with a 95% confidence interval (CI) value ranging from 0.804 to 2.139 and I-2 value of 72.04% were obtained. The pooled relative risk was 1.09, with a 95% CI value ranging from 0.97 to 1.268. The data heterogeneity was assessed, and we achieved a Q value of 33.54, a p value of 0.0004, and I-2 value of 67.21% with a 95% CI value of 32.91-82.10. All these values are statistically significant, with p &lt; 0.005, and confirmed the effectiveness of TCM for TS patients. 

**Conclusion:** 
The present meta-analysis on account of these statistically significant results highly recommends using TCM to treat TS.
AN  - WOS:001037796500008
AU  - Kong,
AU  - M.
AU  - Yan,
AU  - S.
AU  - J.
AU  - Gao,
AU  - Y.
AU  - A.
AU  - Li,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1159/000524377
L1  - internal-pdf://1595575078/Kong-2023-Is Traditional Chinese Medicine Effe.pdf
PY  - 2023
SP  - 248-257
T2  - Complementary Medicine Research
TI  - Is Traditional Chinese Medicine Effective in Treating Tic Disorders (Tourette Syndrome)? A Meta-Analysis of Randomized Controlled Trials
UR  - &lt;Go to ISI&gt;://WOS:001037796500008
UR  - https://karger.com/cmr/article-pdf/30/3/248/3975887/000524377.pdf
VL  - 30
ER  -
TY  - JOUR
AB  - Cognitive behavior therapy (CBT) is by far the most examined type of psychological treatment for depression and is recommended in most treatment guide-lines. However, no recent meta-analysis has integrated the results of randomized trials examining its effects, and its efficacy in comparison with other psychotherapies, pharmacotherapies and combined treatment for depression remains uncertain. We searched PubMed, PsycINFO, Embase and the Cochrane Library to identify studies on CBT, and separated included trials into several subsets to conduct random-effects meta-analyses. We included 409 trials (518 comparisons) with 52,702 patients, thus conducting the largest meta-analysis ever of a specific type of psychotherapy for a mental disorder. The quality of the trials was found to have increased significantly over time (with increasing numbers of trials with low risk of bias, less waitlist control groups, and larger sample sizes). CBT had moderate to large effects compared to control conditions such as care as usual and waitlist (g=0.79; 95% CI: 0.70-0.89), which remained similar in sensitivity analyses and were still significant at 6-12 month follow-up. There was no reduction of the effect size of CBT according to the publication year (&lt;2001 vs. 2001-2010 vs. &gt;2011). CBT was significantly more effective than other psychotherapies, but the difference was small (g=0.06; 95% CI: 0-0.12) and became non-significant in most sensitivity analyses. The effects of CBT did not differ significantly from those of pharmacotherapies at the short term, but were significantly larger at 6-12 month follow-up (g=0.34; 95% CI: 0.09-0.58), although the number of trials was small, and the difference was not significant in all sensitivity analyses. Combined treatment was more effective than pharmacotherapies alone at the short (g=0.51; 95% CI: 0.19-0.84) and long term (g=0.32; 95% CI: 0.09-0.55), but it was not more effective than CBT alone at either time point. CBT was also effective as unguided self-help intervention (g=0.45; 95% CI: 0.31-0.60), in institutional settings (g=0.65; 95% CI: 0.21-1.08), and in children and adolescents (g=0.41; 95% CI: 0.25-0.57). We can conclude that the efficacy of CBT in depression is documented across different formats, ages, target groups, and settings. However, the superiority of CBT over other psychotherapies for depression does not emerge clearly from this meta-analysis. CBT appears to be as effective as pharmacotherapies at the short term, but more effective at the longer term.
AN  - 36640411
AU  - Cuijpers,
AU  - P.
AU  - Miguel,
AU  - C.
AU  - Harrer,
AU  - M.
AU  - Plessen,
AU  - C.
AU  - Y.
AU  - Ciharova,
AU  - M.
AU  - Ebert,
AU  - D.
AU  - Karyotaki,
AU  - E.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/wps.21069
L1  - internal-pdf://3204800171/World Psychiatry - 2023 - Cuijpers - Cognitive.pdf
PY  - 2023
SP  - 105-115
T2  - World Psychiatry
TI  - Cognitive behavior therapy vs. control conditions, other psychotherapies, pharmacotherapies and combined treatment for depression: a comprehensive meta-analysis including 409 trials with 52,702 patients
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36640411
VL  - 22
ER  -
TY  - JOUR
AB  - **Background:** 
Physical exercise has been recommended as an important nonpharmacological therapeutic strategy for managing attention deficit hyperactivity disorder (ADHD). We conducted a network meta-analysis (NMA) to assess the comparative impact of different physical exercise modalities on enhancing executive functions (EFs) and alleviating symptoms in children and adolescents with ADHD. 

**Methods:** 
We searched Web of Science, PubMed, Embase, Cochrane Central Register of Controlled Trials, SPORTDiscus, PsycINFO, CNKI, and clinical trials databases from inception to October 20, 2022. Randomized controlled trials (RCTs) and quasi-experimental studies investigating physical exercise for ADHD-related symptoms of hyperactivity/impulsivity and inattention, and executive functions were included. The frequentist random-effect NMA method was applied to pool the results. 

**Results:** 
A total of 59 studies (including 39 RCTs, 5 quasi-RCTs, and 15 self-controlled trials) published between 1983 and 2022 were incorporated into the systematic review, of which 44 studies with 1757 participants were eligible for meta-analysis. All types of physical exercise were effective in improving EFs (SMD = 1.15, 95% CI: 0.83 to 1.46), and open-skill activities which require participants to react in a dynamically changing and externally paced environment induced the most incredible benefits for executive functions (SUCRA = 98.0%, SMD = 1.96, and 95% CI: 1.15 to 2.77). Subgroup analyses for EFs revealed varied findings that open-skill activities were the most promising physical exercise type for improving inhibitory control (SUCRA = 99.1%, SMD = 1.94, and 95% CI: 1.24 to 2.64), and closed-skill activities dominated by aerobic exercises had a slightly higher probability of being the most promising physical exercise intervention for working memory (SUCRA = 75.9%, SMD = 1.21, and 95% CI: -0.22 to 2.65), and multicomponent physical exercise tended to be the most effective in cognitive flexibility (SUCRA = 70.3%, SMD = 1.44, and 95% CI: -0.19 to 3.07). Regarding ADHD-related symptoms, closed-skill activities dominated by aerobic exercises might be more advantageous for hyperactivity/impulsivity (SUCRA = 72.5%, SMD = -1.60, and 95% CI: -3.02 to -0.19) and inattention (SUCRA = 96.3%, SMD = -1.51, and 95% CI: -2.33 to -0.69) improvement. 

**Conclusion:** 
Physical exercise can significantly help to alleviate the symptoms of ADHD and improve executive functions in children and adolescents with ADHD. Most of all, to promote adherence to treatment, they should be encouraged to perform the physical exercises that they enjoy most. Copyright &copy; 2023 Zhu, Zhu, Bi, Kuang, Liu, Zhou, Yang and Ren.
AN  - 37033046
AU  - Zhu,
AU  - F.
AU  - Zhu,
AU  - X.
AU  - Bi,
AU  - X.
AU  - Kuang,
AU  - D.
AU  - Liu,
AU  - B.
AU  - Zhou,
AU  - J.
AU  - Yang,
AU  - Y.
AU  - Ren,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpubh.2023.1133727
L1  - internal-pdf://0483033617/Zhu-2023-Comparative effectiveness of various.pdf
PY  - 2023
SP  - 1133727
T2  - Frontiers in Public Health
TI  - Comparative effectiveness of various physical exercise interventions on executive functions and related symptoms in children and adolescents with attention deficit hyperactivity disorder: A systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37033046
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10080114/pdf/fpubh-11-1133727.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - BACKGROUND: Existing clinical trials of cognitive behavioural therapies with a trauma focus (CBTs-TF) are underpowered to examine key variables that might moderate treatment effects. We aimed to determine the efficacy of CBTs-TF for young people, relative to passive and active control conditions, and elucidate putative individual-level and treatment-level moderators. 

METHODS: This was an individual participant data meta-analysis of published and unpublished randomised studies in young people aged 6-18 years exposed to trauma. We included studies identified by the latest UK National Institute of Health and Care Excellence guidelines (completed on Jan 29, 2018) and updated their search. The search strategy included database searches restricted to publications between Jan 1, 2018, and Nov 12, 2019; grey literature search of trial registries ClinicalTrials.gov and ISRCTN; preprint archives PsyArXiv and bioRxiv; and use of social media and emails to key authors to identify any unpublished datasets. The primary outcome was post-traumatic stress symptoms after treatment (&lt;1 month after the final session). Predominantly, one-stage random-effects models were fitted. This study is registered with PROSPERO, CRD42019151954. FINDINGS: We identified 38 studies; 25 studies provided individual participant data, comprising 1686 young people (mean age 13.65 years [SD 3.01]), with 802 receiving CBTs-TF and 884 a control condition. The risk-of-bias assessment indicated five studies as low risk and 20 studies with some concerns. Participants who received CBTs-TF had lower mean post-traumatic stress symptoms after treatment than those who received the control conditions, after adjusting for post-traumatic stress symptoms before treatment (b=-13.17, 95% CI -17.84 to -8.50, p&lt;0.001, tau&lt;sup&gt;2&lt;/sup&gt;=103.72). Moderation analysis indicated that this effect of CBTs-TF on post-traumatic stress symptoms post-treatment increased by 0.15 units (b=-0.15, 95% CI -0.29 to -0.01, p=0.041, tau&lt;sup&gt;2&lt;/sup&gt;=0.03) for each unit increase in pre-treatment post-traumatic stress symptoms. 

INTERPRETATION: This is the first individual participant data meta-analysis of young people exposed to trauma. Our findings support CBTs-TF as the first-line treatment, irrespective of age, gender, trauma characteristics, or carer involvement in treatment, with particular benefits for those with higher initial distress. FUNDING: Swiss National Science Foundation.
AN  - 37980918
AU  - de
AU  - Haan,
AU  - A.
AU  - Meiser-Stedman,
AU  - R.
AU  - Landolt,
AU  - M.
AU  - A.
AU  - Kuhn,
AU  - I.
AU  - Black,
AU  - M.
AU  - J.
AU  - Klaus,
AU  - K.
AU  - Patel,
AU  - S.
AU  - D.
AU  - Fisher,
AU  - D.
AU  - J.
AU  - Haag,
AU  - C.
AU  - Ukoumunne,
AU  - O.
AU  - C.
AU  - Jones,
AU  - B.
AU  - G.
AU  - Flaiyah,
AU  - A.
AU  - M.
AU  - Catani,
AU  - C.
AU  - Dawson,
AU  - K.
AU  - Bryant,
AU  - R.
AU  - A.
AU  - de
AU  - Roos,
AU  - C.
AU  - Ertl,
AU  - V.
AU  - Foa,
AU  - E.
AU  - B.
AU  - Ford,
AU  - J.
AU  - D.
AU  - Gilboa-Schechtman,
AU  - E.
AU  - Tutus,
AU  - D.
AU  - Hermenau,
AU  - K.
AU  - Hecker,
AU  - T.
AU  - Hultmann,
AU  - O.
AU  - Axberg,
AU  - U.
AU  - Jaberghaderi,
AU  - N.
AU  - Jensen,
AU  - T.
AU  - K.
AU  - Ormhaug,
AU  - S.
AU  - M.
AU  - Kenardy,
AU  - J.
AU  - Lindauer,
AU  - R.
AU  - J.
AU  - L.
AU  - Diehle,
AU  - J.
AU  - Murray,
AU  - L.
AU  - K.
AU  - Kane,
AU  - J.
AU  - C.
AU  - Peltonen,
AU  - K.
AU  - Kangaslampi,
AU  - S.
AU  - Robjant,
AU  - K.
AU  - Koebach,
AU  - A.
AU  - Rosner,
AU  - R.
AU  - Rossouw,
AU  - J.
AU  - Smith,
AU  - P.
AU  - Tonge,
AU  - B.
AU  - J.
AU  - Hitchcock,
AU  - C.
AU  - Dalgleish,
AU  - T.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/S2352-4642(23)00253-5
L1  - internal-pdf://1065096203/deHaan_2023.pdf
PY  - 2023
SP  - 16
T2  - The Lancet Child &amp; Adolescent Health
TI  - Efficacy and moderators of efficacy of cognitive behavioural therapies with a trauma focus in children and adolescents: an individual participant data meta-analysis of randomised trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37980918
UR  - https://www.sciencedirect.com/science/article/pii/S2352464223002535?via%3Dihub
VL  - 16
ER  -
TY  - JOUR
AB  - OBJECTIVE: Anxiety and pain during medical procedures may have adverse short and long-term consequences. We summarize the effectiveness of hospital clown interventions, as compared with medication, the presence of a parent, standard care, and other non-pharmacological distraction interventions on anxiety and pain in minors undergoing medical procedures. 

METHOD: Randomized trials were identified in PsycINFO, MEDLINE, Embase, Scopus and CINAHL, and previous reviews. Screening of titles and abstracts and full-texts, data extraction and risk of bias assessment was done by two independent reviewers. We conducted random-effects network and pairwise meta-analyses based on a frequentist framework. 

RESULTS: Our analyses with 28 studies showed significantly lower anxiety scores in clowning and other distraction interventions as compared with the presence of parents. No differences were observed between clowning, medication, and other distraction interventions. Clowning interventions were superior to standard care in our main analyses, but non-significant in some of the sensitivity analyses. Furthermore, clowning led to significantly lower pain as compared with presence of parents and standard care. No differences were observed between clowning interventions and the other comparators. For both outcomes, large between study heterogeneity was present but no significant inconsistency between designs. Risk of bias was mainly high and accordingly the certainty of evidence is considered moderate to low. 

CONCLUSIONS: We found no significant difference between medication, other non-medical distraction interventions and hospital clown interventions. Hospital clowns and other distraction interventions were more effective in reducing anxiety and pain in children undergoing medical procedures than the presence of parents alone. In order to allow for better insights regarding the comparative effectiveness of clowning interventions future trials should include detailed descriptions about the clowning intervention itself and the comparator. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
AN  - 37023326
AU  - Caci,
AU  - L.
AU  - Zander-Schellenberg,
AU  - T.
AU  - Gerger,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/hea0001285
L1  - internal-pdf://1072171867/Caci_2023.pdf
PY  - 2023
SP  - 257-269
T2  - Health Psychology
TI  - Effectiveness of hospital clowning on pediatric anxiety and pain: Network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37023326
VL  - 42
ER  -
TY  - JOUR
AB  - Dialogic reading (DR) is an evidence-based interactive shared reading intervention. This systematic review investigated the effect of DR interventions on the communicative initiations and responses of children with autism, an area of great difficulty for most individuals with autism. More precisely, the paper aimed to (a) describe the characteristics of DR interventions, (b) evaluate the outcomes and effectiveness of DR interventions, and (c) synthesize the quality of the studies. Nine experimental studies were included in the review in which the original DR intervention or adapted versions of it were examined. All studies provided strong to adequate research report strength. Although the review showed inconsistent effects of the interventions on the communicative initiations and responses of children with autism, it concluded that DR can be a promising and beneficial shared reading intervention.
AN  - WOS:001048596900001
AU  - Alharbi,
AU  - H.
AU  - Terlektsi,
AU  - E.
AU  - Kossyvaki,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40489-023-00395-1
L1  - internal-pdf://0605218364/Alharbi-2023-Dialogic Reading Effect on Commun.pdf
PY  - 2023
SP  - 21
T2  - Review Journal of Autism and Developmental Disorders
TI  - Dialogic Reading Effect on Communicative Initiations and Responses for Children with Autism: a Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:001048596900001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-023-00395-1.pdf
ER  -
TY  - JOUR
AB  - **Objectives**
Though findings have been mixed, some primary or elementary school-based mindfulness and cognitive behavioural interventions have been shown to improve aspects of emotion regulation. Age is suggested as a potential mediator but previous reviews have not addressed this comprehensively, making evaluation of impact unclear. The current review brought together the evidence surrounding the impact of mindfulness-based interventions (MBIs) or cognitive behavioural interventions (CBIs) on emotion regulation in children aged between 7 and 12 years.

**Method**
Databases (British Education Index, Child Development and Adolescent Studies, CINAHL, Education Source, ERIC, MEDLINE, PsycINFO, PubMed, SAGE, Web of Science) were searched for published and unpublished randomised controlled trials evaluating the effect of primary school-based MBIs (n = 18) or CBIs (n = 12) on measures of emotional awareness, modulation and expression.

**Results**
Analysis of the MBIs in this review indicated a significant improvement in emotional awareness, an increase in positive emotions and a reduction in depression. Sub-analyses found an effect of age, duration and universal delivery for MBIs. Analysis of the CBIs indicated significant improvement in child negative expressive behaviours as reported by parents. Risk of bias was low across domains of incomplete outcome data and selective outcome reporting but was unclear in other domains.

**Conclusions**
Evidence from the MBI studies suggested that universal interventions with a shorter duration had more significant effects, particularly for 10-12-year-old participants. Future research should investigate programme design features and the suitability of content and skill-focus for different age groups, employing qualitative techniques for analysis. This could lead to reconsideration of typical intervention formats for primary school children.Pre-registrationPROSPERO #CRD42019139283.
AN  - WOS:000981359000002
AU  - Pickerell,
AU  - L.
AU  - E.
AU  - Pennington,
AU  - K.
AU  - Cartledge,
AU  - C.
AU  - Miller,
AU  - K.
AU  - A.
AU  - Curtis,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s12671-023-02131-6
L1  - internal-pdf://3205729468/Pickerell-2023-The Effectiveness of School-Bas.pdf
PY  - 2023
SP  - 20
T2  - Mindfulness
TI  - The Effectiveness of School-Based Mindfulness and Cognitive Behavioural Programmes to Improve Emotional Regulation in 7-12-Year-Olds: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000981359000002
UR  - https://link.springer.com/content/pdf/10.1007/s12671-023-02131-6.pdf
ER  -
TY  - JOUR
AB  - Objective: To systematically review the available evidence of the effect of Bach flower remedies (BFR) on the improvement of symptoms and behavior in children and adolescents with attention deficit hyperactivity disorder (ADHD). 

Methods: This systematic review with meta-analysis was developed following PRISMA recommendations and the protocol was registered in PROSPERO. The search for controlled trials was performed in Cochrane Central Register of Controlled Trials, Embase, PubMed and LILACS and in grey literature from their inceptions until March, 2023. The population was children and adolescents diagnosed with ADHD. The intervention included the use BFR and the control included placebo or conventional therapies group. The outcome included improvement of symptoms and behavior. RoB 2.0 was used to assess the risk of bias, while GRADE was used to assess the quality of evidence. Stata version 16.0 was used to perform the meta-analysis. 

Results: Of the 457 studies identified, only 4 studies that met the inclusion criteria remained and were included in the data analysis. The agreement between the reviewers for risk of bias assessment, based on the kappa statistic, was 0.91. Three studies reported improvement in ADHD symptoms with BFR. The studies presented some concerns regarding the risk of bias and the quality of evidence was &quot;low&quot;. The meta-analysis showed a positive effect favoring BFR (z = 2.57, p = 0.01) versus control with an effect size of 0.80 (0.19-1.42:95 %CI). I2 test value was 35.96 %, indicating moderate heterogeneity among the studies. 

Conclusions: BFR can have some effect on ADHD. However, further studies with higher methodological quality and long-term follow-up period are needed to reinforce these findings.
AN  - WOS:001197749300001
AU  - de
AU  - Oliveira,
AU  - F.
AU  - N.
AU  - Okuyama,
AU  - C.
AU  - E.
AU  - Marquez,
AU  - A.
AU  - D.
AU  - Fernandes,
AU  - K.
AU  - B.
AU  - P.
AU  - Dalaqua,
AU  - P.
AU  - V.
AU  - C.
AU  - do
AU  - Carmo,
AU  - A.
AU  - C.
AU  - F.
AU  - Barreiro,
AU  - Fcab
DB  - April 24.enl
DO  - 10.1016/j.aimed.2023.07.001
L1  - internal-pdf://2795188013/1-s2.0-S2212958823000745-main.cleaned.pdf
PY  - 2023
SP  - 93-100
T2  - Advances in Integrative Medicine
TI  - Use of Bach flower remedies in children and adolescents with attention deficit hyperactivity disorder: Systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001197749300001
UR  - https://www.sciencedirect.com/science/article/pii/S2212958823000745?via%3Dihub
VL  - 10
ER  -
TY  - JOUR
AB  - Autism spectrum disorders (ASDs) are a group of neurodevelopmental disorders characterized by increased developmental, educational, and social demands. Recent evidence suggests that up to 40%-50% of symptom variability may be determined by environmental factors including nutritional deficiency of folate, omega-3 fatty acids, and Vitamin D. Studies exist which advocate the use of micronutrient therapy to improve brain function. However, there is no consensus on their use in ASD and opinions remain divisive. This study aims to identify the role of micronutrients in ASD. We searched PubMed, Google Scholar, and Cochrane Library from the period of January 2010 to January 2022. We excluded animal studies, cross-sectional studies, and less 10 participants in a study. An initial literature search yielded a total of 666 studies, out of which 26 studies were included in the systematic review with a pooled sample of 12086 patients. Twelve studies showed an improvement in the symptoms of ASD patients when they were treated with micronutrients and seven studies found an association between micronutrient levels and ASD symptoms. The results of the meta-analysis in seven studies show that micronutrient therapy has a beneficial effect in reducing the severity of ASD, albeit being statistically insignificant (log odds ratio = -1.03, 95% confidence interval: -2.11-0.05). Our study suggests that in spite of low quality of evidence and randomized data, universal micronutrient supplementation may be started in children diagnosed with ASD due to the potential of reducing the severity of ASD along with a low risk of side effects.
AN  - WOS:001197294300002
AU  - Panchawagh,
AU  - S.
AU  - J.
AU  - Kumar,
AU  - P.
AU  - Srikumar,
AU  - S.
AU  - Sarkar,
AU  - M.
AU  - Ashok,
AU  - T.
AU  - Gupta,
AU  - S.
AU  - Shaikh,
AU  - H.
AU  - Soumya,
AU  - K.
AU  - S.
AU  - Poorvikha,
AU  - S.
AU  - Abhishek,
AU  - K.
AU  - Agrawal,
AU  - P.
AU  - Kaushal,
AU  - G.
AU  - P.
AU  - Shah,
AU  - U.
AU  - Shukla,
AU  - R.
AU  - Martinez,
AU  - D.
AU  - Prajapati,
AU  - K.
AU  - Agarwal,
AU  - A.
AU  - Singh,
AU  - K.
AU  - Sharma,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - 10.4103/injms.injms_30_23
L1  - internal-pdf://4245250314/role_of_micronutrients_in_the_management_of_au.pdf
PY  - 2023
SP  - 187-196
T2  - Indian Journal of Medical Specialities
TI  - Role of Micronutrients in the Management of Autism Spectrum Disorders: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001197294300002
VL  - 14
ER  -
TY  - JOUR
AB  - **Objective**
To explore the impact of sports on aggression in children and adolescents and analyze whether different conditions in the intervention, such as type of sports, or intervention duration, have different influences on the effect of interventions. 

**Method:** 
The study protocol was registered in PROSPERO (CRD42022361024). We performed a systematic search of Pubmed, Web of Science, Cochrane library, Embase and Scopus databases from database inception to 12 October 2022 for all studies written in English. Studies were included if they met the following PICO criteria. All analyses were carried out using the Review Manager 5.3 Software. We summarized aggression, hostility and anger scores using SMDs. Summary estimates with 95% confidence intervals were pooled using DerSimonian-Laird random effects model or fixed effects model according to between-study heterogeneity. 

**Results:** 
A total of 15 studies were deemed eligible for inclusion in this review. The overall mean effect size indicated that sport interventions was associated with lower aggression (SMD = -0.37, 95% CI [-0.69 to -0.06], P = 0.020; I&lt;sup&gt;2&lt;/sup&gt; = 88%). Subgroup analyses showed that non-contact sports were associated with lower aggression (SMD = -0.65, 95% CI [-1.17 to -0.13], P = 0.020; I&lt;sup&gt;2&lt;/sup&gt; = 92%) but high-contact sports were not (SMD = -0.15, 95% CI [-0.55 to 0.25], P = 0.470; I&lt;sup&gt;2&lt;/sup&gt; = 79%). In addition, when intervention duration &lt;6 months, sport interventions was associated with lower aggression (SMD = -0.99, 95% CI [-1.73 to -0.26], P = 0.008; I&lt;sup&gt;2&lt;/sup&gt; = 90%) and when intervention duration &gt;= 6 months, sport interventions was not associated with lower aggression (SMD = -0.08, 95% CI [-0.44 to -0.28], P = 0.660; I&lt;sup&gt;2&lt;/sup&gt; = 87%). 

**Conclusion:** 
This review confirmed that sports intervention can reduce the aggression of children and adolescents. We suggested that schools can organize young people to participate in low-level, non-contact sports to reduce the occurrence of bullying, violence and other aggression-related adverse events. Additional studies are needed to determine which other variables are associated with aggression in children and adolescents, in order to develop a more detailed and comprehensive intervention programme to reduce their aggression.
AN  - 37334131
AU  - Yang,
AU  - Y.
AU  - Zhu,
AU  - H.
AU  - Chu,
AU  - K.
AU  - Zheng,
AU  - Y.
AU  - Zhu,
AU  - F.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.7717/peerj.15504
L1  - internal-pdf://3084380448/Yang-2023-Effects of sports intervention on ag.pdf
PY  - 2023
SP  - e15504
T2  - PeerJ
TI  - Effects of sports intervention on aggression in children and adolescents: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37334131
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10274581/pdf/peerj-11-15504.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - BACKGROUND: Repetitive Transcranial magnetic stimulation (rTMS) combined with antidepressants benefited adults with depression while its efficacy and safety in children and adolescents with depression remain controversial.

METHODS: We searched PubMed, Embase, the Cochrane Library, Web of Science, CINAHL, LILACS, PsycINFO, CNKI, Wanfang Data Knowledge Service Platform, a Chinese Biology Medical disc database, and relevant clinical registration databases for randomized controlled trials from their inception to October 18, 2022. The efficacy of the treatment was assessed by changes in depression rating scale scores. Safety was assessed by the incidence of adverse events. Heterogeneity was determined using the Cochrane Q statistics and I2 statistics. Publication bias was assessed by Egger&#039;s test.

RESULTS: Eighteen studies from 10 datasets (1396 patients, 64.7 % female, age range from 8 to 24 years old). The pooled mean-endpoint scores of the depression scale for rTMS combined with the antidepressant group were significantly lower than those of sham combined with the antidepressant group both in two weeks (MD = -4.68, 95 % CI: [-6.66, -2.69]; I2 = 91 %; P &lt; 0.05) and four weeks (MD = -5.53, 95 % CI: [-9.90, -1.16]; I2 = 98 %; P &lt; 0.05). There were no differences in safety (OR = 0.64, 95 % CI: [0.20, 2.04]; I2 = 64 %; P = 0.45) and acceptability between the two groups (3/70 vs 3/70).

LIMITATION: Heterogeneity was found in this study due to the limited number of original studies included.

CONCLUSION: rTMS combined with antidepressants enhanced the efficacy of the antidepressant medication. The safety and acceptability of the two groups were comparable. These findings may help guide future research and clinical practice. Copyright &copy; 2023 The Authors. Published by Elsevier B.V. All rights reserved.
AU  - Cao,
AU  - P.
AU  - Li,
AU  - Y.
AU  - An,
AU  - B.
AU  - Ye,
AU  - L.
AU  - Xu,
AU  - Z.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2023.05.051
L1  - internal-pdf://3063776945/1-s2.0-S0165032723006924-main.cleaned.pdf
PY  - 2023
SP  - 25-34
T2  - Journal of Affective Disorders
TI  - Efficacy and safety of repetitive transcranial magnetic stimulation combined with antidepressants in children and adolescents with depression: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37211054
UR  - https://www.sciencedirect.com/science/article/pii/S0165032723006924?via%3Dihub
VL  - 336
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Substance use amongst young people poses developmental and clinical challenges, necessitating early detection and treatment. Considering the widespread use of technology in young people, delivering interventions digitally may help to reduce and monitor their substance use. AIMS: We conducted a systematic review and two meta-analyses to assess the effectiveness of digital interventions for reducing substance use (alcohol, smoking, and other substances) among young people aged 10 to 24 years old. 

METHOD: 
Embase, Global Health, Medline, PsychINFO, Web of Science and reference lists of relevant papers were searched in November 2020. Studies were included if they quantitatively evaluated the effectiveness of digital health technologies for treating substance use. A narrative synthesis and meta-analysis were conducted. 

RESULTS: 
Forty-two studies were included in the systematic review and 18 in the meta-analyses. Digital interventions showed small, but statistically significant reductions in weekly alcohol consumption compared to controls (SMD= -0.12, 95% CI= -0.17 to -0.06, I&lt;sup&gt;2&lt;/sup&gt;=0%), but no overall effect was seen on 30-day smoking abstinence (OR = 1.12, 95% CI = 0.70 to 1.80, I&lt;sup&gt;2&lt;/sup&gt;=81%). The effectiveness of digital interventions for reducing substance use is generally weak, however, promising results such as reducing alcohol use were seen. Large-scale studies should investigate the viability of digital interventions, collect user feedback, and determine cost-effectiveness. 

PRISMA/PROSPERO: 
This systematic review was conducted following Cochrane methodology PRISMA guidelines. The review was registered with PROSPERO in November 2020 (CRD42020218442).
AN  - 37664884
AU  - O&#039;Logbon,
AU  - J.
AU  - Wickersham,
AU  - A.
AU  - Williamson,
AU  - C.
AU  - Leightley,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/09638237.2023.2245902
L1  - internal-pdf://1817318278/O&#039;Logbon-2023-The effectiveness of digital hea.pdf
PY  - 2023
SP  - 1-29
T2  - Journal of Mental Health
TI  - The effectiveness of digital health technologies for reducing substance use among young people: a systematic review &amp; meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37664884
UR  - https://www.tandfonline.com/doi/pdf/10.1080/09638237.2023.2245902
ER  -
TY  - JOUR
AB  - **BAKGRUNN**
Denne artikkelen er en kunnskapsoppsummering og klassifisering av tiltaket Cool Kids, et program med hovedmålsetting å hjelpe barn og unge i alderen 6&ndash;18 år i å håndtere angst og relaterte vansker. Programmet kan tilbys både individuelt og i gruppeformat, med ca. 10 møter. Cool Kids-programmet er teoretisk forankret i kognitiv adferdsterapi. Sentrale metoder i programmet omfatter psykoedukasjon, kognitiv restrukturering, eksponering og inkludering av foreldre. Opplæring, godkjenning av veiledere og godkjenning som Cool Kids-terapeut tilbys gratis av RKBU Vest. Programmet tilbys per i dag i Norge i kommunehelsetjenesten, skolehelsetjenesten og spesialisthelsetjenesten

**METODE**
Kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

**RESULTATER**
Litteratursøket resulterte i 220 treff hvorav totalt 9 artikler ble inkludert, åtte nordiske effektstudier og en kunnskapsoppsummering. Cool Kids er detaljert beskrevet og er teoretisk forankret i kognitiv atferdsterapi, som har bred forskningsstøtte som behandling for angstlidelser. Studiene av Cool Kids holder god forskningsmetodisk kvalitet, med før, etter, og oppfølgingsmålinger, relevante og utprøvde måleinstrumenter og et multiinformant perspektiv i flertallet av studiene. Studiene ble gjennomført både i en klinisk gruppe og en gruppe som fikk indikert forebyggende (barn og ungdom som skårer over en terskelverdi på angst) tiltak. I flertallet av studiene var det en statistisk signifikant forskjell mellom intervensjonsgruppen (Cool Kids) og sammenligningsgruppen. Både i en klinisk og i en indikert forebyggende kontekst ble det påvist små til store effektstørrelser. Oppfølgingsstudier viser at effektnivået i stor grad opprettholdes over tid.

**KONKLUSJON**
Cool Kids er et evidensbasert tiltak som har et solid teoretisk fundament. Programmet er godt beskrevet. Resultater fra nordiske effektstudier tyder på at programmet kan bidra til reduksjon av angst og depresjonssymptom sammenlignet med vanlig behandling og effekten er vist å holde seg over tid for flere hoved utfallsmål. Cool Kids klassifiseres på evidensnivå 5 &ndash; Tiltak med sterk dokumentasjon på effekt.
AU  - Kaasbøll,
AU  - J.
AU  - Brøndbo,
AU  - P.
AU  - H.
DB  - Rekoding IN SUM_lme.enl
DO  - /post_tiltak_arkiv/cool-kids-1-utg/
L1  - internal-pdf://0507190328/Cool-Kids-1-utg.cleaned.pdf
PY  - 2023
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Cool Kids (1. utg)
ER  -
TY  - JOUR
AB  - INTRODUCTION: 
Over the last years, videoconference-delivered psychotherapy (VCP) has found its way into clinical practice. This meta-analysis is the first to evaluate the effectiveness of VCP for children and adolescents with a mental disorder and their parents. 

METHODS: 
A systematic literature search was performed to identify randomized controlled trials (RCTs) that compared the effectiveness of VCP for youths with a mental disorder to a control condition. Twelve studies were included. Two reviewers independently extracted data and rated study quality. 

RESULTS: 
Effect size estimates for measures of children&#039;s symptoms of mental disorders were large for comparison between VCP and waitlist (posttreatment: Hedges&#039;s g = -1.26, k = 5) and negligible for comparisons between VCP and in-person treatment (posttreatment: g = 0.00, k = 6; follow-up: g = -0.05, k = 3). Similarly, effect size estimates for measures of children&#039;s functional impairments were large for comparison between VCP and waitlist (posttreatment: g = -1.10, k = 3) and negligible for comparisons between VCP and in-person treatment (posttreatment: g = -0.23, k = 3; follow-up: g = 0.04, k = 2). VCP more effectively reduced symptoms in children with an internalizing disorder (g = -0.88, k = 5) compared to externalizing disorders (g = 0.25, k = 2) or tic disorders (g = -0.08, k = 3). 

DISCUSSION: 
The results provide preliminary evidence that VCP is an effective treatment for youths with a mental disorder and their parents. VCP was equally effective as in-person treatment in reducing children&#039;s symptoms and functional impairments. Limitations include the limited number of RCTs and incomplete reporting of methodological features.
AN  - 37715649
AU  - von
AU  - Wirth,
AU  - E.
AU  - Willems,
AU  - S.
AU  - Dopfner,
AU  - M.
AU  - Kohl,
AU  - L.
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1357633X231199784
L1  - internal-pdf://1392259688/Wirth_2023.pdf
PY  - 2023
SP  - 1357633X231199784
T2  - Journal of Telemedicine &amp; Telecare
TI  - Effectiveness of videoconference-delivered psychotherapy for children, adolescents, and their parents: A meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37715649
UR  - https://journals.sagepub.com/doi/10.1177/1357633X231199784
ER  -
TY  - JOUR
AB  - Digital parenting programs aim to increase program access, improve psychosocial outcomes for parents and children, and support triage to targeted interventions where required. This meta-analysis assessed the efficacy of online parenting programs in improving parenting skills and capabilities, and by consequence, the mental health and well-being of parents and children, and the quality of the parent-child relationship. 

Studies were included if they were: (1) online, (2) self-delivered, (3) designed for universal general population prevention, (4) evaluated experimental or quasi-experimental designs, and (5) assessed parent and child emotional and/or relational health, from pregnancy to 5 years of age. A systematic search of electronic databases and grey literature identified 22 studies that met inclusion criteria, including 24 independent samples, with 5671 unique parents. Meta-analyses were conducted using random effects models and Cohen&#039;s d effects. 

Small-to-moderate improvements in parent depression, anxiety, self-efficacy, and social support were observed. No effects on parent stress, satisfaction, or parent-child relationship quality were observed. Meta-regression and sub-group analysis were conducted to identify sensitivity or moderation effects. 

Collectively, findings suggest any benefits of online parenting programs mostly occur at the time of the intervention, for parent mental health and well-being outcomes, and that enduring effects are unlikely. However, given the cost effectiveness and accessibility of online programs, further research into ways of sustaining effects on parenting outcomes is warranted. Furthermore, given the centrality of the parent-child bond to child development across the lifecourse, additional investment in new digitally facilitated approaches focusing on this bond are likewise warranted.PROSPERO registration CRD42021275647.
AN  - WOS:001093029700001
AU  - Opie,
AU  - J.
AU  - E.
AU  - Esler,
AU  - T.
AU  - B.
AU  - Clancy,
AU  - E.
AU  - M.
AU  - Wright,
AU  - B.
AU  - Painter,
AU  - F.
AU  - Vuong,
AU  - A.
AU  - Booth,
AU  - A.
AU  - T.
AU  - Newman,
AU  - L.
AU  - Johns-Hayden,
AU  - A.
AU  - Hameed,
AU  - M.
AU  - Hooker,
AU  - L.
AU  - Olsson,
AU  - C.
AU  - McIntosh,
AU  - J.
AU  - E.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1007/s10567-023-00457-0
L1  - internal-pdf://3938131797/Opie-2023-Universal Digital Programs for Promo.pdf
N1  - Kristine Ludvigsen (2023-12-07 22:08:11)(Screen): relevant tiltak og utfall målt på barn (samspill/tilknytning) skal inn;
PY  - 2023
SP  - 30
T2  - Clinical Child and Family Psychology Review
TI  - Universal Digital Programs for Promoting Mental and Relational Health for Parents of Young Children: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001093029700001
UR  - https://link.springer.com/content/pdf/10.1007/s10567-023-00457-0.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: Procedural pain is very important in clinical children care. We aimed to evaluate the effects of active versus passive distraction for reducing procedural pain and anxiety in children. 

METHODS: Two researchers searched the Web of Science, PubMed, EMBASE, Cochrane, SinoMed, Wanfang, China National Knowledge Infrastructure, Weipu databases for the randomized controlled trials(RCTs) on the active versus passive distraction affecting procedural pain and anxiety in children until May 18, 2023. The literature screening and data extraction were carried out by two researchers independently. Review Manager 5.3 software was used for data analysis. 

RESULTS: 13 RCTs were finally included. 553 children received active distraction intervention and 551 children received passive distraction intervention. There were no significant differences in the children self-reported procedural pain betweent active and passive distraction. The parent-reported procedural pain, medical staff-reported procedural pain, children-reported procedural anxiety, parent-reported procedural anxiety, medical staff-reported procedural anxiety in the active distraction were significant less than that of active distraction. Egger regression analysis showed that there was no publication bias in the results. 

CONCLUSIONS: Existing evidence suggests that active distraction may be more effective in reducing operational pain and anxiety in children than passive distraction. More studies on the effects of active distraction versus passive distraction in children with larger sample size are needed in the future.
AN  - 37653423
AU  - Shen,
AU  - T.
AU  - Wang,
AU  - X.
AU  - Xue,
AU  - Q.
AU  - Chen,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s13052-023-01518-4
L1  - internal-pdf://3028101674/Shen-2023-Active versus passive distraction fo.pdf
PY  - 2023
SP  - 109
T2  - Italian Journal of Pediatrics
TI  - Active versus passive distraction for reducing procedural pain and anxiety in children: a meta-analysis and systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37653423
UR  - https://ijponline.biomedcentral.com/counter/pdf/10.1186/s13052-023-01518-4.pdf
VL  - 49
ER  -
TY  - JOUR
AB  - Early social-behavioral intervention that emphasizes social skill training is critical to addressing emotional and behavioral problems in early childhood. In this meta-analysis review, we examined all the social skills intervention studies for preschoolers with, or at risk of, emotional and behavioral problems using group designs. This review included 25 studies that met the inclusion criteria. The robust variance estimation method was used to calculate the overall effect size of all the included studies, as this method can count for the pre-existing difference between the experiment and control groups. The included studies yielded an overall effect of 0.54 from the 151 effect sizes that were obtained for the 3484 preschool participants. Curriculum, integration, and treatment fidelity were identified as significant moderators of effects.
AN  - 37998686
AU  - Dong,
AU  - X.
AU  - Burke,
AU  - M.
AU  - D.
AU  - Ramirez,
AU  - G.
AU  - Xu,
AU  - Z.
AU  - Bowman-Perrott,
AU  - L.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/bs13110940
L1  - internal-pdf://3351319797/Dong-2023-A Meta-Analysis of Social Skills Int.pdf
PY  - 2023
SP  - 16
T2  - Behavioral Sciences
TI  - A Meta-Analysis of Social Skills Interventions for Preschoolers with or at Risk of Early Emotional and Behavioral Problems
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37998686
UR  - https://mdpi-res.com/d_attachment/behavsci/behavsci-13-00940/article_deploy/behavsci-13-00940.pdf?version=1700137204
VL  - 13
ER  -
TY  - JOUR
AB  - BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most common neurological and mental developmental disorders in children. Published systematic reviews (SRs) and meta-analyses (MAs) concerning the use of acupuncture for ADHD have compared the efficacy of acupuncture treatment to that of drug therapies. However, the quality of these articles has not been evaluated and the evidence varies widely.

OBJECTIVE: To summarize and assess the efficacy of acupuncture for ADHD based on existing SRs and MAs. 

METHODS: A systematic search of the literature was conducted from inception until September 16 2021, using seven electronic databases. The AMSTAR-2 tool was used to evaluate the quality of SRs and MAs, and the GRADE system was used to assess the quality of evidence. RESULTS: There are a total of five SRs and MAs included in this overview. Using the AMSTAR-2, three articles were rated as having &#039;Low&#039; quality, while two were rated as having of &#039;Critically Low&#039; quality. The GRADE system was used to measure the quality of evidence for ten outcomes (five response rate outcomes, three Conners&#039; Index of Hyperactivity (CIH) score outcomes, one Conners&#039; rating scale score outcome, and one Chinese medicine syndrome outcome) across the five included MAs. Four of the ten outcomes demonstrated &#039;moderate&#039; quality, four demonstrated &#039;low&#039; quality, and two demonstrated &#039;very low&#039; quality. The risk of bias and inconsistency accounted for most downgrading factors in the included reviews. 

CONCLUSION: It is still debatable whether acupuncture is efficacious in improving the CIH score and the Response rate. Considering the heterogeneity of clinical trials and the fact that this study did not search and evaluate the relevant data of each randomized controlled trial, large-sample and high-quality randomized controlled trials are still needed to draw reliable conclusions regarding acupuncture&#039;s role in treating ADHD. Due to the poor quality of existing available evidence, little inference can be drawn from the included studies.
AN  - 37562658
AU  - Zhang,
AU  - L.
AU  - Huang,
AU  - C.
AU  - Chen,
AU  - X.
AU  - Du,
AU  - S.
AU  - Yang,
AU  - J.
AU  - Hu,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ctim.2023.102968
L1  - internal-pdf://1883813437/Zhang_2023.pdf
PY  - 2023
SP  - 102968
T2  - Complementary Therapies in Medicine
TI  - The efficacy of acupuncture for attention deficit hyperactivity disorder (ADHD): An overview of systematic reviews and meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37562658
UR  - https://www.sciencedirect.com/science/article/pii/S0965229923000559?via%3Dihub
VL  - 76
ER  -
TY  - JOUR
AB  - **Background:** 
Cognitive behavioral therapy (CBT) is the recommended treatment for depression in patients with epilepsy (PWE). However, there are no studies that calculate the effect size of CBT on depression and quality of life (QoL) in PWE. 

**Methods:** 
We searched seven electronic databases (PubMed, Web of Science, Embase, Cochrane Library, Clinical Trials, Ovid Medline, and PsycINFO). We included 13 studies examining CBT for depression in PWE and calculated its effect size. 

**Results:** A total of 13 studies met the criteria. After treatment, CBT improves depression in PWE (g = 0.36, 95%CI: 0.18 to 0.54, I2 = 50%), and the efficacy maintains during follow-up (g = 0.47, 95%CI: 0.04 to 0.89, I2 = 80%). Subgroup analysis has shown that individual CBT (g = 0.47, 95%CI: 0.20 to 0.73, I2 = 0%) had a greater effect size than group CBT (g = 0.30, 95%CI: 0.07 to 0.53, I2 = 62%) in the treatment of depression. Likewise, CBT has a positive effect on the QoL improvement of PWE (g = 0.34, 95%CI: 0.11 to 0.57, I2 = 64%). In controlling seizures, CBT did not differ from the control group (g =-0.06, 95%CI:-0.32 to 0.19, I2 = 0%). 

**Conclusions:** 
Cognitive behavioral therapy interventions were effective in improving depression and QoL in PWE, but not effective in controlling seizures. The efficacy of CBT interventions targeting seizure con-trol seems to be uncertain. (c) 2022 Elsevier Inc. All rights reserved.
AN  - WOS:000914061900001
AU  - Li,
AU  - D.
AU  - X.
AU  - Song,
AU  - Y.
AU  - Q.
AU  - Zhang,
AU  - S.
AU  - Y.
AU  - Qiu,
AU  - J.
AU  - Zhang,
AU  - R.
AU  - Wu,
AU  - J.
AU  - Y.
AU  - Wu,
AU  - Z.
AU  - Y.
AU  - Wei,
AU  - J.
AU  - W.
AU  - Xiang,
AU  - X.
AU  - F.
AU  - Zhang,
AU  - Y.
AU  - Yu,
AU  - L.
AU  - D.
AU  - Wang,
AU  - H.
AU  - H.
AU  - Niu,
AU  - P.
AU  - Fan,
AU  - C.
AU  - Li,
AU  - X.
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1016/j.yebeh.2022.109056
L1  - internal-pdf://1413285054/1-s2.0-S1525505022005054-main.cleaned.pdf
PY  - 2023
SP  - 8
T2  - Epilepsy &amp; Behavior
TI  - Cognitive behavior therapy for depression in people with epilepsy: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000914061900001
VL  - 138
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
To determine the effect of early childhood development interventions delivered by healthcare providers (HCP-ECD) on child cognition and maternal mental health. DESIGN: Systematic review, meta-analysis. 

**SETTING**
Healthcare setting or home. 

**PARTICIPANTS**
Infants under 1 month of age. 

**INTERVENTIONS**
HCP-ECD interventions that supported responsive caregiving, early learning and motor stimulation. MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Health Technology Assessment Database, Database of Abstracts of Reviews of Effects and Cochrane Database of Systematic Reviews were searched until 15 November 2021. Studies reporting prespecified outcomes were pooled using standard meta-analytical methods. 

**MAIN OUTCOME MEASURES**
Cognitive development in children at 0-36 months. 

**RESULTS**
Forty-two randomised controlled trials with 15 557 infants were included in the narrative synthesis. Twenty-seven trials were included in the meta-analyses. Pooled data from 13 trials suggest that HCP-ECD interventions may improve cognitive outcomes in children between 0 and 36 months (Bayley Scales of Infant Development version IIII (BSID-III) mean difference (MD) 2.65; 95% CI 0.61 to 4.70; 2482 participants; low certainty of evidence). Pooled data from nine trials suggest improvements in motor development (BSID-III MD 4.01; 95% CI 1.54 to 6.48; 1437 participants; low certainty of evidence). There was no evidence of improvement in maternal mental health (standardised MD -0.13; 95% CI -0.28 to 0.03; 2806 participants; 11 trials; low certainty of evidence). 

**CONCLUSIONS**
We report promising evidence, particularly for cognitive and motor outcomes, of the effect of HCP-ECD interventions. However, effect sizes were small, and the certainty of evidence ranged from very low to moderate. Additional high-quality research is required. Prospero registration number: Crd42019122021.
AN  - 36732037
AU  - Hirve,
AU  - R.
AU  - Adams,
AU  - C.
AU  - Kelly,
AU  - C.
AU  - B.
AU  - McAullay,
AU  - D.
AU  - Hurt,
AU  - L.
AU  - Edmond,
AU  - K.
AU  - M.
AU  - Strobel,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/archdischild-2022-324506
L1  - internal-pdf://1249295549/Hirve-2023-Effect of early childhood developme.pdf
PY  - 2023
SP  - 02
T2  - Archives of Disease in Childhood
TI  - Effect of early childhood development interventions delivered by healthcare providers to improve cognitive outcomes in children at 0-36 months: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36732037
UR  - https://adc.bmj.com/content/archdischild/early/2023/02/02/archdischild-2022-324506.full.pdf
VL  - 02
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Iron deficiency is negatively associated with children&#039;s cognitive development. Evidence showed that iron supplementation improves cognitive development. Nearly 50% of anemia is caused by iron deficiency. Anemia affects more school-age children, at an age where their brain development continues. The aim of this systematic review and meta-analysis is to review the evidence from published randomized controlled trials to evaluate the effects of iron supplementation on cognitive development and function among school-age children. 

METHOD: 
Five databases including MEDLINE, EMBASE, Scopus, Web of Science and CENTRAL were used to search for articles on April 20th, 2021. The search was reconducted on October 13th, 2022 to retrieve new records. Studies were eligible if they included school children 6-12 years of age, were randomized controlled trials, and if they tested iron supplementation and measured cognitive development. 

RESULT: 
Thirteen articles were included in the systematic review. Overall, iron supplementation significantly improved intelligence (standardized mean difference, 95% confidence interval) (SMD 0.46, 95%CI: 0.19, 0.73, P&lt;0.001), attention and concentration (SMD 0.44, 95%CI: 0.07, 0.81, P = 0.02) and memory (SMD 0.44, 95%CI: 0.21, 0.67, P &lt;0.001) of school-age children. There was no significant effect of iron supplementation on school achievement of school-age children (SMD 0.06, 95%CI: -0.15, 0.26, P = 0.56). In a subgroup analysis, iron-supplemented children who were anemic at baseline had had better outcomes of intelligence (SMD 0.79, 95%CI: 0.41, 1.16, P = 0.001) and memory (SMD 0.47, 95%CI: 0.13, 0.81; P = 0.006). 

CONCLUSION: 
Iron supplementation has a significant positive effect on the intelligence, attention and concentration, and the memory of school-age children but there was no evidence on the effect of iron supplementation on their school achievement.
AN  - 37368919
AU  - Gutema,
AU  - B.
AU  - T.
AU  - Sorrie,
AU  - M.
AU  - B.
AU  - Megersa,
AU  - N.
AU  - D.
AU  - Yesera,
AU  - G.
AU  - E.
AU  - Yeshitila,
AU  - Y.
AU  - G.
AU  - Pauwels,
AU  - N.
AU  - S.
AU  - De
AU  - Henauw,
AU  - S.
AU  - Abbeddou,
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1371/journal.pone.0287703
L1  - internal-pdf://3532969025/Gutema-2023-Effects of iron supplementation on.pdf
PY  - 2023
SP  - e0287703
T2  - PLoS ONE [Electronic Resource]
TI  - Effects of iron supplementation on cognitive development in school-age children: Systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=37368919
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287703&amp;type=printable
VL  - 18
ER  -
TY  - JOUR
AB  - **Background**
People with disabilities&mdash;more than a billion people worldwide&mdash;are frequently excluded from social and political life, and often experience stigmatising attitudes and behaviours from people without disabilities. This stigma, coupled with inaccessible environments and systems and institutional barriers (e.g., lack of inclusive legislation), may result in discrimination against people with disabilities (and their families) to the degree that they are not able to enjoy their rights on an equal basis with others.

**Objectives**
This review examines the effectiveness of interventions for improving social inclusion outcomes (acquisition of skills for social inclusion, broad-based social inclusion, and improved relationships) for people with disabilities in low- and middle-income countries (LMICs).

**Search Methods**
We searched academic and online databases, carried out citation tracking of included studies, and contacted experts to ensure our search was as comprehensive as possible. We also ran the searches with search terms specific to social inclusion review using Open Alex in EPPI reviewer.

Selection Criteria
We included all studies which reported on impact evaluations of interventions to improve social inclusion outcomes for people with disabilities in LMIC.

**Data Collection and Analysis**
We used review management software EPPI Reviewer to screen the search results. Two review authors independently extracted the data from each study report, including for the confidence in study findings appraisal. Data and information were extracted regarding available characteristics of participants, intervention characteristics and control conditions, research design, sample size, risk of bias and outcomes, and results. Random-effects inverse variance weighted meta-analytic methods were used to synthesise standardised mean differences for the outcomes.

**Main Results**
We identified 37 experimental and quasi-experimental studies. Studies were conducted in 16 countries, with the majority of the included studies (n&thinsp;=&thinsp;13) from South Asia and nine each from East Asia, the Pacific, the Middle East, and North Africa. Most studies targeted children with disabilities (n&thinsp;=&thinsp;23), and 12 targeted adults with disabilities. Most focused on people with intellectual disabilities (n&thinsp;=&thinsp;20) and psychosocial disabilities (n&thinsp;=&thinsp;13). Regarding intervention content, most (n&thinsp;=&thinsp;17) of the included programmes aimed to improve the social and communication skills of people with disabilities through social skills training programmes. Ten studies aimed at providing personal assistance and support and evaluated the effects of a parent training programme on the interactive skills of parents of children and their children with disabilities. We calculated effect sizes from experimental and quasi-experimental studies for outcomes on skills for social inclusion, relationships of people with disabilities with family and community members, and broad-based social inclusion among people with disabilities. A meta-analysis of 16 studies indicates an overall positive, statistically significant and large effect of the interventions for skills for social inclusion with standardised mean difference (SMD)&thinsp;=&thinsp;0.87, confidence interval (CI)&thinsp;=&thinsp;0.57 to 1.16, k&thinsp;=&thinsp;26, I2&thinsp;=&thinsp;77%, p&thinsp;&lt;&thinsp;0.001). For relationships across 12 studies, we find a positive but moderate effect (SMD&thinsp;=&thinsp;0.61, CI&thinsp;=&thinsp;0.41 to 0.80, k&thinsp;=&thinsp;15, I2&thinsp;=&thinsp;64%, p&thinsp;&lt;&thinsp;0.01). As for the overall effect on broad-based social inclusion, we find the average effect size was large, and there was significant dispersion across studies (SMD&thinsp;=&thinsp;0.72, CI&thinsp;=&thinsp;0.33 to 1.11, k&thinsp;=&thinsp;2, I2&thinsp;=&thinsp;93%, p&thinsp;&lt;&thinsp;0.01). Despite the significant and large effects estimated by the studies, some limitations must be noted. Although there was a consensus on the direction of the effects, the studies presented considerable heterogeneity in the size of the effects. A majority (n&thinsp;=&thinsp;27) of studies were assessed to be of low confidence related to methodological limitations, so the findings must be interpreted with caution. Tests for publication bias show that the effect sizes of social skills (p&thinsp;&lt;&thinsp;0.01) and social inclusion (p&thinsp;=&thinsp;0.01) are all likely to be inflated by the existence of the publication bias.

**Authors&rsquo; Conclusions**
The review&#039;s findings suggest that various interventions to improve the social inclusion of people with disabilities have a significant positive effect. Interventions such as social and communication training and personal assistance led to significant improvement in the social behaviour and social skills of people with disabilities. Studies targeting broad-based social inclusion showed a large and significant positive effect. A moderate effect was reported from interventions designed to improve relationships between people with disabilities and their families and communities. However, the findings of this review must be interpreted cautiously, given the low confidence in study methods, severe heterogeneity and significant publication bias. The available evidence focused primarily on individual-level barriers such as interventions for improving social or communications skills of people with disabilities and not the systemic drivers of exclusions such as addressing societal barriers to inclusion, such as stigma reduction, and interventions to strengthen legislation, infrastructure, and institutions.
AU  - Saran,
AU  - A.
AU  - Hunt,
AU  - X.
AU  - White,
AU  - H.
AU  - Kuper,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/cl2.1316
L1  - internal-pdf://0940129774/Campbell Systematic Reviews - 2023 - Saran - E.pdf
PY  - 2023
T2  - Campbell Systematic Reviews
TI  - Effectiveness of interventions for improving social inclusion outcomes for people with disabilities in low- and middle-income countries: A systematic review
ER  -
TY  - JOUR
AB  - **Background:** 
Parent-mediated telehealth interventions can provide caregivers of children with autism spectrum disorder (ASD) with support and the training required to care for autistic children. Although many studies demonstrated the effects of telehealth on autistic children, metaanalyses of the benefits to parents are lacking. Aim: To examine the effects of telehealth on parents of autistic children in terms of fidelity in parents and problem behaviors in autistic children. 

**Methods:** 
We conducted a systematic search in PubMed, EMBASE, and Cochrane library in July 2022. Data were analyzed using RevMan 5.4, and changes in implementation fidelity, selfefficacy, and stress in parents and behavioral problems in autistic children were compared and quality assessment was conducted. 

**Results:** 
17 controlled trials were included in this meta-analysis. The parent implementation fidelity (p = .003, CI = 0.58-2.74) and self-efficacy (p = .005, CI = 0.11-0.63) significantly increased and parent stress (p = .02, CI = -1.23 to -0.10) and children&#039;s problem behaviors significantly decreased (p = .002, CI = -2.70 to -0.60) in the telehealth group compared with the control group. Eight articles indicated the feasibility of using telehealth interventions. No significant differences were noted between the telehealth and face-to-face groups. 

**Conclusion:** 
Telehealth interventions improved the implementation fidelity and self-efficacy and reduced the stress of parents of autistic children. However, the differences in their effects between the telehealth and face-to-face groups must be analyzed in future studies.
AN  - WOS:001053423800001
AU  - Pan,
AU  - C.
AU  - Y.
AU  - Kuo,
AU  - T.
AU  - Y.
AU  - Kuo,
AU  - F.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.rasd.2023.102209
L1  - internal-pdf://3929611047/Pan_2023.pdf
PY  - 2023
SP  - 18
T2  - Research in Autism Spectrum Disorders
TI  - Meta-analysis of effectiveness of parent-mediated telehealth interventions in children with Autism spectrum disorder
UR  - &lt;Go to ISI&gt;://WOS:001053423800001
UR  - https://www.sciencedirect.com/science/article/pii/S1750946723001095?via%3Dihub
VL  - 107
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Attention-deficit/hyperactivity disorder (ADHD) is relatively common among school-age children. Technology-based interventions, such as computer-assisted training programs, neurofeedback training, and virtual reality, show promise in regulating the behaviors and cognitive functions of children with ADHD. An increasing number of randomized controlled trials have been conducted to evaluate the effectiveness of these technologies in improving the conditions of children with ADHD. 

**OBJECTIVE**
This study aims to conduct a systematic review of technological interventions for school-age children with ADHD and perform a meta-analysis of the outcomes of technology-based interventions. 

**METHODS**
A total of 19 randomized controlled studies involving 1843 participants were selected from a pool of 2404 articles across 7 electronic databases spanning from their inception to April 2022. ADHD behaviors, cognitive functions, learning ability, and quality of life were addressed in this study. 

**RESULTS**
Random effects meta-analyses found that children with ADHD receiving technology-based intervention showed small and significant effect sizes in computer-rated inattention (standardized mean difference [SMD] -0.35; P&lt;.04), parent-rated overall executive function measured by the Behavior Rating Inventory of Executive Function (SMD -0.35; P&lt;.04), parent-rated disruptive behavior disorder measured by the Child Behavior Checklist (SMD -0.50; P&lt;.001) and Disruptive Behavior Disorder Rating Scale (SMD -0.31; P&lt;.02), and computer-rated visual attention measured by the Continuous Performance Test (SMD -0.42; P&lt;.001) and Reaction Time (SMD -0.43; P&lt;.02). 

**CONCLUSIONS**
Technology-based interventions are promising treatments for improving certain ADHD behaviors and cognitive functions among school-age children with ADHD. TRIAL REGISTRATION: PROSPERO CRD42023446924; https://tinyurl.com/7ee5t24n.
AN  - 37988139
AU  - Wong,
AU  - K.
AU  - P.
AU  - Qin,
AU  - J.
AU  - Xie,
AU  - Y.
AU  - J.
AU  - Zhang,
AU  - B.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.2196/51459
L1  - internal-pdf://3949994751/PDF.cleaned (8).pdf
PY  - 2023
SP  - e51459
T2  - JMIR Mental Health
TI  - Effectiveness of Technology-Based Interventions for School-Age Children With Attention-Deficit/Hyperactivity Disorder: Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37988139
VL  - 10
ER  -
TY  - JOUR
AB  - **Objective:** 
Previous studies have shown conflicting results for the effectiveness of omega-3 polyunsaturated fatty acids (PUFAs) in improving attention-deficit/hyperactivity disorder (ADHD) symptoms. This inconsistency may be due to differences in dosage, composition, and treatment duration. The current meta-analysis aims to address this inconsistency by improving subtype analyses and focusing on heterogeneity in treatment duration, omega-3 PUFA composition, and eicosapentaenoic acid (EPA) dose. 

**Data Sources and Study Selection:** 
We searched PubMed, EMBASE, PsycINFO, and Cochrane Library for randomized controlled trials of omega-3 PUFAs for ADHD, without publication year or language limitations, up to November 27, 2022. The primary outcome was the improvement of ADHD core symptoms. Subgroup analyses were conducted based on the formula, dosages, and composition ratios of omega-3 PUFAs. To ensure methodological quality, the Cochrane Risk-of-Bias Tool 1.0 was utilized to assess the risk of bias for each study included in the analysis. The pooled data were then analyzed using the random-effect meta-analysis, and the inverse variance method was employed. 

**Data Extraction:** 
The outcomes of interest were extracted using a data extraction form developed for this study. 

**Results:** 
Twenty-two studies with 1,789 participants were included in the analysis. Overall, omega-3 PUFAs did not significantly improve ADHD core symptoms compared to placebo (standardized mean difference [SMD]: -0.16; 95% CI,-0.34 to 0.01; P= .07). However, in the subgroup of studies with a treatment duration of at least 4 months, omega-3 PUFAs were significantly more effective than placebo (SMD:-0.35; 95% CI,-0.61 to-0.09; P=.007). Neither high eicosapentaenoic acid (EPA) dosage nor high EPA/ docosahexaenoic acid (DHA) ratio was found to improve ADHD symptoms. 

**Conclusions:** 
Our findings indicate that omega-3 PUFAs did not improve ADHD core symptoms, but long-term supplementation may have potential benefits. The main limitation of the study was the moderate heterogeneity and small sample sizes in subgroup analyses and the lack of dietary pattern information.
AN  - WOS:001164732400004
AU  - Liu,
AU  - T.
AU  - H.
AU  - Wu,
AU  - J.
AU  - Y.
AU  - Huang,
AU  - P.
AU  - Y.
AU  - Lai,
AU  - C.
AU  - C.
AU  - Chang,
AU  - J.
AU  - P.
AU  - C.
AU  - Lin,
AU  - C.
AU  - H.
AU  - Su,
AU  - K.
AU  - P.
DB  - Mars 24.enl
DO  - 10.4088/JCP.22r14772
L1  - internal-pdf://1628554891/Polyunsaturated-Fatty-Acids-Attention-Deficit-.pdf
PY  - 2023
SP  - 16
T2  - Journal of Clinical Psychiatry
TI  - Omega-3 Polyunsaturated Fatty Acids for Core Symptoms of Attention-Deficit/ Hyperactivity Disorder: A Meta-Analysis of Randomized Controlled Trials
UR  - &lt;Go to ISI&gt;://WOS:001164732400004
VL  - 84
ER  -
TY  - JOUR
AB  - AIM: This systematic review investigates behaviour change techniques in interventions promoting physical activity for young people aged 12-25 years at heightened risk of problematic substance use, and the effect of these techniques on physical activity participation and substance use outcomes. 

METHODS: Four databases (PsycINFO, CINAHL, SPORTDiscus and Medline) were searched between November 2020 and November 2022 for randomized and non-randomized controlled studies according to inclusion criteria. Meta-analyses were calculated using weighted, standardized averages of effect sizes (Hedges&#039; g). 

RESULTS: Twenty-eight studies were included, 14 studies in the meta-analysis (intervention n = 1328; control n = 845). Reported BCTs included behavioural instructions, social comparison and goal setting. There was a significant effect of behaviour change techniques on combined substance use outcomes, such as cravings and consumption, for interventions reporting multiple behaviour change techniques (g = -0.33, p &lt; .001, 95% CI [-0.50,-0.16]) or one single behaviour change technique (g = -1.84, p &lt; .001, 95% CI [-2.89,-0.8]). Limitations include unexplained variance and limited reporting of relevant behaviour change technique data in the included studies. 

CONCLUSION: The results indicate that using behaviour change techniques in interventions that promote physical activity for young people has an effect on substance use. Further research needs to be completed comparing the impact of the number and type of behaviour change technique, and improved reporting of intervention content is required.
AN  - 37749782
AU  - Klamert,
AU  - L.
AU  - Craike,
AU  - M.
AU  - Bedi,
AU  - G.
AU  - Kidd,
AU  - S.
AU  - Pascoe,
AU  - M.
AU  - C.
AU  - Parker,
AU  - A.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/eip.13467
L1  - internal-pdf://1606025010/Klamert-2023-Behaviour change techniques in ph.pdf
PY  - 2023
SP  - 25
T2  - Early intervention in psychiatry
TI  - Behaviour change techniques in physical activity-focused interventions for young people at risk of problematic substance use: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37749782
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/eip.13467?download=true
VL  - 25
ER  -
TY  - JOUR
AB  - Melatonin is a potential therapeutic intervention for improving sleep quality in people with autistic spectrum disorder (ASD). We investigate the effect of using melatonin as a sleep disorder treatment in people with ASD. Interventionist studies were searched in seven databases. A total of 595 references were identified, 15 of which were eligible for the systemic review and meta-analysis. Melatonin use presented a positive effect on total sleep time (standardized mean difference- SMD = 0.78; 95%CI = 0.35; 1.21; I2 = 91%), on sleep latency (SMD = 1.23; 95%CI = 0.35; 2.11; I2 = 94%), and on sleep efficiency (SMD = -0.70; 95%CI = -1.23; -0.16; I2 = 91%) when comparing the intervention group with the placebo/control group via the global analysis. According to the global analysis, the wake after sleep onset and night awakening parameters were not statistically significant. Melatonin has possible efficacy over total time, latency, and efficiency sleep parameters.
AN  - WOS:000993874500001
AU  - Nogueira,
AU  - H.
AU  - A.
AU  - de
AU  - Castro,
AU  - C.
AU  - T.
AU  - da
AU  - Guimara,
AU  - D.
AU  - C.
AU  - G.
AU  - Pereira,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1016/j.pnpbp.2022.110695
L1  - internal-pdf://2569723068/1-s2.0-S0278584622001877-main.cleaned (1).pdf
PY  - 2023
SP  - 11
T2  - Progress in Neuro-Psychopharmacology &amp; Biological Psychiatry
TI  - Melatonin for sleep disorders in people with autism: Systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000993874500001
VL  - 123
ER  -
TY  - JOUR
AB  - **Background**
Autism spectrum disorder (autism) is a neurodevelopmental condition characterised by impairments in social communication and interaction, plus restricted, repetitive patterns of behaviour and interests. Whilst some people embrace autism as part of their identity, others struggle with their difficulties, and some seek treatment. There are no current interventions that result in complete reduction of autism features.

Acetylcholine is a neurotransmitter for the cholinergic system and has a role in attention, novelty seeking, and memory. Low levels of acetylcholine have been investigated as a potential contributor to autism symptomatology. Donepezil, galantamine, and rivastigmine (commonly referred to as acetylcholinesterase inhibitors) all inhibit acetylcholinesterase, and have slightly different modes of action and biological availability, so their effectiveness and side‐effect profiles may vary. The effect of various acetylcholinesterase inhibitor on core autism features across the lifespan, and possible adverse effects, have not been thoroughly investigated.

**Objectives**
To evaluate the efficacy and harms of acetylcholinesterase inhibitors for people with the core features (social interaction, communication, and restrictive and repetitive behaviours) of autism.

To assess the effects of acetylcholinesterase inhibitors on non‐core features of autism.

**Search methods**
In November 2022, we searched CENTRAL, MEDLINE, Embase, eight other databases, and two trials registers. We also searched the reference lists of included studies and relevant reviews, and contacted authors of relevant studies.

**Selection criteria**
Randomised controlled trials (RCTs), comparing acetylcholinesterase inhibitors (e.g. galantamine, donepezil, or rivastigmine) of varying doses, delivered orally or via transdermal patch, either as monotherapy or adjunct therapy, with placebo. People of any age, with a clinical diagnosis of autism were eligible for inclusion.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane. Our primary outcomes were core features of autism and adverse effects. Secondary outcomes were language, irritability, hyperactivity, and general health and function. We used GRADE to assess certainty of evidence.

**Main results**
We included two RCTs (74 participants). One study was conducted in Iran, the second in the USA, although exact location in the USA is unclear.

Galantamine plus risperidone versus placebo plus risperidone

One study compared the effects of galantamine plus risperidone to placebo plus risperidone (40 participants, aged 4 years to 12 years). Primary and secondary outcomes of interest were measured postintervention, using subscales of the Aberrant Behavior Checklist (score 0 to 3; higher scores = greater impairment). Very low‐certainty evidence showed there was little to no difference between the two groups postintervention for social communication (mean difference (MD) ‐2.75, 95% confidence interval (CI) ‐5.88 to 0.38), and restricted and repetitive behaviour (MD ‐0.55, 95% CI ‐3.47 to 2.37). Overall autism features were not assessed. Adverse events may be higher in the galantamine plus risperidone group (75%) compared with the placebo plus risperidone group (35%): odds ratio 5.57, 95% CI 1.42 to 21.86, low‐certainty evidence. No serious adverse events were reported. Low‐certainty evidence showed a small difference in irritability (MD ‐3.50, 95% CI ‐6.39 to ‐0.61), with the galantamine plus risperidone group showing a greater decline on the irritability subscale than the placebo group postintervention. There was no evidence of a difference between the groups in hyperactivity postintervention (MD ‐5.20, 95% CI ‐10.51 to 0.11). General health and function were not assessed.

Donepezil versus placebo

One study compared donepezil to placebo (34 participants aged 8 years to 17 years). Primary outcomes of interest were measured postintervention, using subscales of the Modified Version of The Real Life Rating Scale (scored 0 to 3; higher scores = greater impairment). Very low‐certainty evidence showed no evidence of group differences immediately postintervention in overall autism features (MD 0.07, 95% CI ‐0.19 to 0.33), or in the autism symptom domains of social communication (MD ‐0.02, 95% CI ‐0.34 to 0.30), and restricted and repetitive behaviours (MD 0.04, 95% CI ‐0.27 to 0.35). Significant adverse events leading to study withdrawal in at least one participant was implied in the data analysis section, but not explicitly reported. The evidence is very uncertain about the effect of donepezil, compared to placebo, on the secondary outcomes of interest, including irritability (MD 1.08, 95% CI ‐0.41 to 2.57), hyperactivity (MD 2.60, 95% CI 0.50 to 4.70), and general health and function (MD 0.03, 95% CI ‐0.48 to 0.54) postintervention.

Across all analyses within this comparison, we judged the evidence to be very low‐certainty due to high risk of bias, and very serious imprecision (results based on one small study with wide confidence intervals). The study narratively reported adverse events for the study as a whole, rather than by treatment group.

**Authors&#039; conclusions**
Evidence about the effectiveness of acetylcholinesterase inhibitors as a medication to improve outcomes for autistic adults is lacking, and for autistic children is very uncertain.

There is a need for more evidence of improvement in outcomes of relevance to clinical care, autistic people, and their families. There are a number of ongoing studies involving acetylcholinesterase inhibitors, and future updates of this review may add to the current evidence.
AU  - Ure,
AU  - A.
AU  - Cox,
AU  - C.
AU  - R.
AU  - Haslam,
AU  - R.
AU  - Williams,
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD013851.pub2
L1  - internal-pdf://1581835764/Ure_et_al-2023-Cochrane_Database_of_Systematic.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Acetylcholinesterase inhibitors for autistic spectrum disorders
ER  -
TY  - JOUR
AB  - Since the 1970s, hundreds of randomized trials have examined the effects of psychotherapies for depression, and this number is increasing every year. In this study, we report outcomes from a living systematic review of these studies. We use Poisson regression analyses to examine if the proportions of studies have changed over time across the characteristics of the participants, therapies, and studies. We also present a meta-analysis of the effects across the major types, formats, targets, and age groups. We included 562 randomized controlled trials (669 comparisons; 66,361 patients). Most trials are conducted in adults and the relative proportion of trials in children and adolescents, as well as in older patients is significantly decreasing. The effects in children and adolescents are also significantly smaller than in adults (p = .007). Cognitive behavior therapy (CBT) is by far the best examined type of therapy (52%), but not necessarily more effective than other therapies. Over time, the proportion of studies examining several other types of therapy is significantly decreased compared to CBT. The quality of trials has increased over time, but still, a majority do not meet basic quality criteria, not even in recent years. The effects found in studies with low risk of bias are significantly smaller than in other studies (b = -0.21; SE = 0.05; p &lt; .001). Most trials are conducted in the United States, but the proportion of studies in other parts of the world is rapidly increasing. The evidence that psychotherapies are effective is strong and growing every year. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
AN  - 37971844
AU  - Cuijpers,
AU  - P.
AU  - Harrer,
AU  - M.
AU  - Miguel,
AU  - C.
AU  - Ciharova,
AU  - M.
AU  - Karyotaki,
AU  - E.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1037/amp0001250
L1  - internal-pdf://3317895906/2024-26478-001.cleaned (1).pdf
PY  - 2023
SP  - 16
T2  - American Psychologist
TI  - Five decades of research on psychological treatments of depression: A historical and meta-analytic overview
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37971844
VL  - 16
ER  -
TY  - JOUR
AB  - Conduct problems (CP) constitute a major field for child clinical psychology, in terms of not only prevalence, but also developmental, social, and clinical relevance. This study carried out an umbrella review of meta-analyses on the efficacy of treatment/indicated prevention of child CP (mean age range up to 12 years). Following a registered protocol, several databases (i.e., Web of Science, PsycINFO, PROSPERO, and The Cochrane Library) were searched for meta-analyses published from January 2002 to March 2022. Nine meta-analytic publications met the required criteria, and the main characteristics and findings of the studies were systematically described. Weighted effect sizes (ESs) were calculated through RStudio program. Analyses of heterogeneity, publication bias, quality (AMSTAR-2), and credibility were also conducted. Results indicate that parent training has been the most studied intervention, with a weighted ES of d = -0.49 (95% CI -.67 to -.32). The reviewed studies identified several moderators for the efficacy of parent training, including individual (severity of CP), family (financial disadvantage), and intervention (delivery format) characteristics. Results from child-centered play therapy were also analyzed, d = -.34 (95% CI -.40 to -.28), but the reduced number of meta-analyses and the weakness detected by quality assessment suggest the need of cautiously considering the pooled effects. In general, evidence seems to be suggestive of the efficacy of treatment of CP, particularly for parent training. Nevertheless, efficacy seems to be moderate, heterogeneity indexes are high, and quality assessments of meta-analyses are often suboptimal. This study suggests several avenues to strengthen knowledge in this field.
AN  - WOS:000975493000003
AU  - Romero,
AU  - E.
AU  - Alvarez-Voces,
AU  - M.
AU  - Diaz-Vazquez,
AU  - B.
AU  - Lopez-Romero,
AU  - L.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.21134/rpcna.2023.10.1.1
L1  - internal-pdf://3055084294/Romero-2023-What works in the psychological tr.pdf
PY  - 2023
SP  - 9-19
T2  - Revista De Psicologia Clinica Con Ninos Y Adolescentes
TI  - What works in the psychological treatment of child conduct problems? An umbrella review of meta-analytic studies
UR  - &lt;Go to ISI&gt;://WOS:000975493000003
VL  - 10
ER  -
TY  - JOUR
AB  - **Background** 
Robust synthesis of evidence to support treatment recommendations for preschoolers with attention-deficit/hyperactivity disorder (ADHD) is lacking. The aim of this systematic review and meta-analysis was to review currently available evidence to evaluate the efficacy and acceptability of stimulants for preschool children with ADHD. 

**Methods** 
We searched electronic databases (CENTRAL, Embase, PubMed) from the database inception to March, 2022; and clinical trial registries through WHO ICTRP from the database inception to July, 2022, and selected double-blinded randomized controlled trials (RCTs) that compared stimulants against placebo for the treatment of preschoolers (age &lt;= 7 years) with ADHD. Change in ADHD symptom severity was the primary outcome (efficacy) and all-cause dropout rates (acceptability) was the secondary outcome. Data were pooled with random-effects models weighted by the inverse of the variance. Risk of bias of individual studies were assessed with the Cochrane Risk of Bias tool version 2. The Grading of Recommendations Assessment, Development, and Evaluation approach was used to assess the quality of evidence. This study is registered with PROSPERO (CRD42022348597). 

**Results** 
Five RCTs (three methylphenidate immediate-release, one methylphenidate extended-release, and one lisdexamfetamine) were included. The analysis of efficacy was based on 489 participants. Meta-analysis of change in ADHD symptom severity demonstrated a significant effect in favor of stimulants over placebo (standardized mean difference = -0.59; 95% CI -0.77, -0.41; p &lt; 0.0001). There was no evidence of heterogeneity but some concerns about publication bias. Regardless, the confidence of evidence was considered moderate. For acceptability, stimulants did not lead to an increased rate of all-cause discontinuation rates in comparison to placebo (OR = 0.59; 95% CI 0.15, 2.37; p = 0.45) but the confidence of estimate was very low. 

**Conclusions** 
Our findings demonstrated that stimulants are efficacious in reducing ADHD symptoms among preschool children. Clinicians should consider the use of stimulants when making treatment recommendations for preschoolers with ADHD. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-51290-001
AU  - Sugaya,
AU  - L.
AU  - S.
AU  - Farhat,
AU  - L.
AU  - C.
AU  - Califano,
AU  - P.
AU  - Polanczyk,
AU  - G.
AU  - V.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/jcv2.12146
L1  - internal-pdf://0580504821/Sugaya-2023-Efficacy of stimulants for prescho.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - JCPP Advances
TI  - Efficacy of stimulants for preschool attention-deficit/hyperactivity disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-51290-001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcv2.12146?download=true
ER  -
TY  - JOUR
AB  - *&#039;BAKGRUNN**

Denne artikkelen er en kunnskapsoppsummering om effekten av søskenintervensjonen SIBS til søsken til barn med kroniske helsetilstander. Intervensjonen baserer seg på familiesystemisk teori med elementer fra resiliensteori, familiekommunikasjon, forståelse av sykdom og helsekunnskap samt kognitiv atferdsterapi. Intervensjonen er et manualbasert gruppetiltak der søsken og en forelder deltar over fem økter. Tre av de fem øktene er separate barne- og foreldregrupper. Det overordnede målet er å styrke kvaliteten på kommunikasjonen mellom foreldre og barn for slik å redusere risiko for utvikling av psykiske plager hos søsken som pårørende. Tiltaket er utviklet av Frambu kompetansesenter for sjeldne diagnoser som gir opplæring i tiltaket og utdanner gruppeledere. Det eies av Frambu og Universitetet i Oslo.

**METODE**

Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

**RESULTATER**

En nordisk studie av tiltaket SIBS ble identifisert og inkludert. Studien som hadde et pre-posttest design uten kontrollgruppe, var gjennomført i Norge og inkluderte søsken-foreldre dyader. Tiltaket er godt beskrevet i manualer, og tiltaket har en tilstrekkelig teoretisk begrunnelse. Studien er samlet sett evaluert til å ha tilstrekkelig forskningsmetodisk kvalitet, men noe svakere indre og ytre validitet grunnet mangel på kontrollgruppe, høyt frafall og kjennetegn ved familiene. Effektstørrelsene i studien var små til moderate. Tiltaket har samlet sett god implementeringsstrategi, men mangler spesifisering av hvordan etterlevelse av kjernekomponentene i tiltaket sikres og hvordan førstelinjen kan registrerer utbytte og vedlikehold av effekter hos deltakere.

**KONKLUSJON**

Hovedfunn fra den nordiske studien var bedring i kvaliteten på foreldre-søsken kommunikasjon over tid. Sekundære funn var bedring i søskens psykiske helsesymptomer og tilpasning til funksjonsnedsettelsen, samt økt kunnskap om funksjonsnedsettelsen. Det vurderes at det er indikasjon på at tiltaket er virksomt, men effektstudier som inkluderer kontrollgruppe er nødvendig for å slå fast at tiltaket er virksomt for mange i målgruppen.SIBS klassifiseres på evidensnivå 3 &ndash; som et tiltak med noe dokumentasjon på effekt.
AU  - Halvorsen,
AU  - M.
AU  - B.
AU  - Lauritzen,
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - /post_tiltak_arkiv/sibs-soskenprosjektet-1-utg/
L1  - internal-pdf://0947131962/SIBS-Soskenprosjektet.cleaned.pdf
PY  - 2023
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: SIBS Søskenprosjektet (1. utg)
ER  -
TY  - JOUR
AB  - Growing evidence suggests an association between inflammatory processes and depressive disorders (DD). DD typically emerge during adolescence. Treatment effects of agents with anti-inflammatory properties in youth DD have not been systematically reviewed. Here, the existing evidence on the use of anti-inflammatory drugs (including polyunsaturated fatty acids, nonsteroidal anti-inflammatory drugs, cytokine inhibitors, statins, pioglitazone, corticosteroids, and minocycline or modafinil) in children and adolescents with DD was synthesized using meta-analysis. The PROSPERO preregistered search yielded 22 records meeting search criteria. Of these, data from 19 primary studies (n = 1366 subjects) were subjected to meta-analysis. A significant but small effect in favor of anti-inflammatory agents in reducing depressive symptoms in youth with DD was found (SMD = -0.29, 95 % CI = -0.514; -0.063, p = 0.01). Post-hoc analyzes of drug subclasses found a significant effect of omega-3 fatty acids in reducing depressive symptoms. Results underline the importance to consider inflammatory pathways in the supplemental treatment of youth with DD. Further research is warranted, to clarify if anti-inflammatory agents are only effective in a subpopulation of patients (inflammatory biotype of depression in youth) and/or to alleviate specific symptom domains of depression (e.g., cognitive symptoms).
AD  - Vockel, Jasper. University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Germany. Electronic address: jasper.voeckel@uk-koeln.de.Markser, Anna. University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Germany.Wege, Lisa. University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Germany.Wunram, Heidrun Lioba. University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Germany; University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Pediatrics, Germany.Sigrist, Christine. University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Germany.Koenig, Julian. University of Cologne, Faculty of Medicine and University Hospital Cologne, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Germany.
AN  - 37864981
AU  - Vockel,
AU  - J.
AU  - Markser,
AU  - A.
AU  - Wege,
AU  - L.
AU  - Wunram,
AU  - H.
AU  - L.
AU  - Sigrist,
AU  - C.
AU  - Koenig,
AU  - J.
DA  - Oct 19
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.euroneuro.2023.09.006
DP  - Ovid Technologies
J2  - Eur Neuropsychopharmacol
L1  - internal-pdf://2237423074/1-s2.0-S0924977X23006879-main.cleaned.pdf
LA  - English
M3  - Review
N1  - Vockel, JasperMarkser, AnnaWege, LisaWunram, Heidrun LiobaSigrist, ChristineKoenig, JulianS0924-977X(23)00687-9
PY  - 2023
SP  - 16-29
T2  - European Neuropsychopharmacology
TI  - Pharmacological anti-inflammatory treatment in children and adolescents with depressive symptoms: A systematic-review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37864981
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37864981&amp;id=doi:10.1016%2Fj.euroneuro.2023.09.006&amp;issn=0924-977X&amp;isbn=&amp;volume=78&amp;issue=&amp;spage=16&amp;pages=16-29&amp;date=2023&amp;title=European+Neuropsychopharmacology&amp;atitle=Pharmacological+anti-inflammatory+treatment+in+children+and+adolescents+with+depressive+symptoms%3A+A+systematic-review+and+meta-analysis.&amp;aulast=Vockel&amp;pid=%3Cauthor%3EVockel+J%3C%2Fauthor%3E%3CAN%3E37864981%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/pii/S0924977X23006879?via%3Dihub
VL  - 78
ER  -
TY  - JOUR
AB  - **Background** 
Previous meta-analyses of psychotherapies for children and adolescents with post-traumatic stress disorder (PTSD) did not investigate whether treatment efficacy is diminished when patients report multiple (versus single) traumas. 

**Aims** 
To examine whether efficacy of psychological interventions for paediatric PTSD is diminished when patients report multiple (versus single) traumas. 

**Method** 
We systematically searched PsycInfo, MEDLINE, Web of Science and PTSDpubs on 21 April 2022 and included randomised controlled trials (RCTs) meeting the following criteria: (a) random allocation; (b) all participants presented with partial or full PTSD; (c) PTSD is the primary treatment focus; (d) sample mean age &lt;19 years; (e) sample size n &gt;= 20. Trauma frequency was analysed as a dichotomous (single versus &gt;=2 traumas) and continuous (mean number of exposures) potential moderator of efficacy. 

**Results** 
Of the 57 eligible RCTs (n = 4295), 51 RCTs were included in quantitative analyses. Relative to passive control conditions, interventions were found effective for single-trauma-related PTSD (Hedges&#039; g = 1.09; 95% CI 0.70-1.48; k = 8 trials) and multiple-trauma-related PTSD (g = 1.11; 95% CI 0.74-1.47; k = 12). Psychotherapies were also more effective than active control conditions in reducing multiple-trauma-related PTSD. Comparison with active control conditions regarding single-event PTSD was not possible owing to scarcity (k = 1) of available trials. Efficacy did not differ with trauma exposure frequency irrespective of its operationalisation and subgroup analyses (e.g. trauma-focused cognitive-behavioural therapy only). 

**Conclusions** 
The current evidence base suggests that psychological interventions for paediatric PTSD can effectively treat PTSD in populations reporting single and multiple traumas. Future trials for PTSD following single-event trauma need to involve active control conditions. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-52384-001
AU  - Hoppen,
AU  - T.
AU  - H.
AU  - Meiser-Stedman,
AU  - R.
AU  - Jensen,
AU  - T.
AU  - K.
AU  - Birkeland,
AU  - M.
AU  - S.
AU  - Morina,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/bjp.2023.24
L1  - internal-pdf://3679367722/Hoppen-2023-Efficacy of psychological interven.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - The British Journal of Psychiatry
TI  - Efficacy of psychological interventions for post-traumatic stress disorder in children and adolescents exposed to single versus multiple traumas: Meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-52384-001
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/D2C852F813966D2A719413DBA809CBD9/S0007125023000247a.pdf/div-class-title-efficacy-of-psychological-interventions-for-post-traumatic-stress-disorder-in-children-and-adolescents-exposed-to-single-versus-multiple-traumas-meta-analysis-of-randomised-controlled-trials-div.pdf
ER  -
TY  - JOUR
AB  - Eating disorders (EDs) are high prevalent among adolescents with serious consequences. Evidence of effectiveness of psychological interventions for eating disorders in adolescents lacks a systematic synthesis of systematic reviews. The goal of this umbrella review is to summarize evidence from systematic reviews examining effects of psychological interventions for eating disorders targeting adolescents. Web of Science, PsycINFO and Cochrane Database of Systematic Reviews were searched for systematic reviews on effectiveness and/or efficacy of any psychological intervention aiming to treat eating disorders in terms of outcomes in adolescents (improvement of eating-disorder symptoms, weight restoration and treatment retention). The methodological quality of each study was assessed using AMSTAR 2. The original search identified 831 reviews, 9 of which were included in the overview of systematic reviews rated as having a low methodological quality. Predominant psychological interventions for EDs in adolescents are family-based interventions. The efficacy of cognitive behavioral therapy and third-wave treatments has been less researched. Anorexia nervosa and bulimia nervosa are the EDs that have been studied the most. This study provides evidence supporting the positive impact of psychological interventions on eating disorders in adolescents. Family based treatment is the most evidence-based psychological intervention. There is a need for high-quality systematic reviews as well as systematic reviews to examine if psychological interventions are effective for different eating disorders.
AN  - WOS:000975493000001
AU  - Garcia-Fernandez,
AU  - G.
AU  - Krotter,
AU  - A.
AU  - Udeanu,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.21134/rpcna.2023.10.1.10
L1  - internal-pdf://0868143708/Garcia-Fernande-2023-Effectiveness of psycholo.pdf
PY  - 2023
SP  - 116-126
T2  - Revista De Psicologia Clinica Con Ninos Y Adolescentes
TI  - Effectiveness of psychological interventions for eating disorders in adolescence: An overview of systematic reviews
UR  - &lt;Go to ISI&gt;://WOS:000975493000001
VL  - 10
ER  -
TY  - JOUR
AB  - BACKGROUND AND AIMS: 
Binge drinking is a widespread practice among adolescents worldwide and is associated with various harmful consequences. Theory-based interventions are a promising approach to prevent this drinking behaviour in this population. The aim of the present review was to determine: (1) the characteristics of theory-based interventions targeting binge drinking in adolescents, (2) the impact of such interventions on binge drinking, and (3) the quality of theoretical implementation. 

METHODS: 
For this systematic review, randomised controlled trials were eligible for inclusion if the binge drinking-targeting intervention was based at least on one theoretical framework, and if the population&#039;s mean age was between 10 and 18 years. Two authors extracted relevant data. A meta-analysis was conducted to evaluate the effect of interventions on binge drinking. Effect sizes were calculated with the Hedges&#039;s g. Binge drinking was measured as a continuous or dichotomous outcome. The quality of theoretical implementation of interventions was measured using an existing &quot;theory coding scheme&quot;. 

RESULTS: 
Sixteen studies were identified. Ten were based on a single theory, and six on a combination of theories. The number and type of behaviour change techniques used in each intervention varied greatly. Theory-based interventions led to a small but significant decrease in binge drinking (Hedges&#039;s g = 0.10; 95% confidence interval = 0.04, 0.16). The quality of theoretical implementation was globally low, and the reciprocal link between behaviour change techniques and theoretical constructs was unclear for most studies. 

CONCLUSIONS: 
Theory-based interventions have a small but significant beneficial impact on decreasing binge drinking in adolescents. Future research should try to be more effective in matching theoretical determinants of behaviour with the content of the intervention.
AN  - 36455407
AU  - Gourlan,
AU  - M.
AU  - Ricupero,
AU  - S.
AU  - Carayol,
AU  - M.
AU  - Cousson-Gelie,
AU  - F.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.socscimed.2022.115571
L1  - internal-pdf://1887667861/1-s2.0-S0277953622008772-main.cleaned.pdf
PY  - 2023
SP  - 115571
T2  - Social Science &amp; Medicine
TI  - Efficacy of theory-based interventions aimed at reducing binge drinking in adolescents: A systematic review and meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36455407
VL  - 317
ER  -
TY  - JOUR
AB  - This meta-analytic review aimed to investigate the effectiveness of gamified interventions in bolstering mental health. 

The gamification and the control groups were compared in terms of the between-group differences in posttest scores of both mental wellness (subjective well-being and quality of life) and psychological symptoms (anxiety and depressive symptoms). 

The review analyzed 42 studies involving 5792 participants (aged 8-74) across eight world regions. The random-effects meta-analysis revealed an overall small to medium effect size (Hedges&#039; g = 0.38; 95% CI: 0.22, 0.55; k = 141). The benefits of gamification in enhancing mental wellness were independent of both game and demographic characteristics, but there were intricate findings for studies examining the benefits of gamification in reducing psychological symptoms. For anxiety symptom reduction, the effects were larger (vs. smaller) in studies adopting specific (vs. general) measures of anxiety and in samples comprising a higher (vs. lower) proportion of males (ps &lt; .04). For depressive symptom reduction, the effects were larger (vs. smaller) in non-clinical (vs. clinical) samples (p = .01). 

These new findings are promising in showing the viability of gamification in promoting mental wellness, encouraging greater collaborations among scholars, practitioners, and game developers to contribute to the growing field of gamification science by co -designing more effective gamified interventions.
AN  - WOS:000918421600001
AU  - Cheng,
AU  - C.
AU  - Ebrahimi,
AU  - O.
AU  - V.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.chb.2022.107621
L1  - internal-pdf://2616570742/1-s2.0-S0747563222004411-main.cleaned.pdf
PY  - 2023
SP  - 17
T2  - Computers in Human Behavior
TI  - A meta-analytic review of gamified interventions in mental health enhancement
UR  - &lt;Go to ISI&gt;://WOS:000918421600001
VL  - 141
ER  -
TY  - JOUR
AB  - **Objective:**

The aim of this systematic review and meta-analysis was to systematically investigate the intervention effect of physical exercise on disordered social communication in patients with autism spectrum disorders. 

**Methods:**

This systematic review and meta-analysis used the PubMed, Web of Science, the Cochrane Library, and Embase electronic databases to conduct a systematic search of literature describing randomized controlled trials (RCTs) on the effect of physical exercise on disordered social communication in autistic patients from the first year of inclusion to 21 January 2023. 

**Results:**

A total of 14 RCTs including 460 autistic patients were analyzed. A meta-analysis showed that physical exercise had a positive effect on social communication disorder (SMD = 0.45, 95% CI: 0.15, 0.74, p &lt; 0.05) in autistic patients. Subgroup analysis showed that exercise programs with multiple components (SMD = 0.73, 95% CI: 0.39, 1.06, P &lt; 0.001), a moderate duration (SMD = 0.73, 95% CI: 0.38, 1.08, P &lt; 0.001), a moderate-high frequency (SMD = 0.84, 95% CI: 0.53, 1.14, P &lt; 0.001), and a long duration (SMD = 0.77, 95% CI: 0.36, 1.18, P &lt; 0.001) led to significant improvement. 

**Conclusion:**

Physical exercise can improve disordered social communication in patients with autism spectrum disorders. Specifically, early intervention, multi-component exercise, a moderate period, moderate and high frequency, long duration, and multi-participant programs were most effective. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/ RecordID= CRD42023422482.
AN  - 37456563
AU  - Jia,
AU  - S.
AU  - Guo,
AU  - C.
AU  - Li,
AU  - S.
AU  - Zhou,
AU  - X.
AU  - Wang,
AU  - X.
AU  - Wang,
AU  - Q.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fped.2023.1193648
L1  - internal-pdf://2149521829/Jia-2023-The effect of physical exercise on di.pdf
PY  - 2023
SP  - 1193648
T2  - Frontiers in Pediatrics
TI  - The effect of physical exercise on disordered social communication in individuals with autism Spectrum disorder: a systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37456563
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347521/pdf/fped-11-1193648.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **AIMS:**

This study aimed to summarize the evidence on sleep alterations in medication-naive children and adolescents with autism spectrum disorder (ASD). 

**METHODS:**

 We systematically searched PubMed/Medline, Embase and Web of Science databases from inception through March 22, 2021. This study was registered with PROSPERO (CRD42021243881). Any observational study was included that enrolled medication-naive children and adolescents with ASD and compared objective (actigraphy and polysomnography) or subjective sleep parameters with typically developing (TD) counterparts. We extracted relevant data such as the study design and outcome measures. The methodological quality was assessed through the Newcastle-Ottawa Scale (NOS). A meta-analysis was carried out using the random-effects model by pooling effect sizes as Hedges&#039; g. To assess publication bias, Egger&#039;s test and p-curve analysis were done. A priori planned meta-regression and subgroup analysis were also performed to identify potential moderators. 

**RESULTS:**

Out of 4277 retrieved references, 16 studies were eligible with 981 ASD patients and 1220 TD individuals. The analysis of objective measures showed that medication-naive ASD patients had significantly longer sleep latency (Hedges&#039; g 0.59; 95% confidence interval [95% CI] 0.26 to 0.92), reduced sleep efficiency (Hedges&#039; g -0.58; 95% CI -0.87 to -0.28), time in bed (Hedges&#039; g -0.64; 95% CI -1.02 to -0.26) and total sleep time (Hedges&#039; g -0.64; 95% CI -1.01 to -0.27). The analysis of subjective measures showed that they had more problems in daytime sleepiness (Hedges&#039; g 0.48; 95% CI 0.26 to 0.71), sleep latency (Hedges&#039; g 1.15; 95% CI 0.72 to 1.58), initiating and maintaining sleep (Hedges&#039; g 0.86; 95% CI 0.39 to 1.33) and sleep hyperhidrosis (Hedges&#039; g 0.48; 95% CI 0.29 to 0.66). Potential publication bias was detected for sleep latency, sleep period time and total sleep time measured by polysomnography. Some sleep alterations were moderated by age, sex and concurrent intellectual disability. The median NOS score was 8 (interquartile range 7.25-8.75). 

**CONCLUSION:**

We found that medication-naive children and adolescents with ASD presented significantly more subjective and objective sleep alterations compared to TD and identified possible moderators of these differences. Future research requires an analysis of how these sleep alterations are linked to core symptom severity and comorbid behavioural problems, which would provide an integrated therapeutic intervention for ASD. However, our results should be interpreted in light of the potential publication bias.
AN  - 37469173
AU  - Kim,
AU  - H.
AU  - Kim,
AU  - J.
AU  - H.
AU  - Kim,
AU  - J.
AU  - Kim,
AU  - J.
AU  - Y.
AU  - Cortese,
AU  - S.
AU  - Smith,
AU  - L.
AU  - Koyanagi,
AU  - A.
AU  - Radua,
AU  - J.
AU  - Fusar-Poli,
AU  - P.
AU  - Carvalho,
AU  - A.
AU  - F.
AU  - Salazar
AU  - de
AU  - Pablo,
AU  - G.
AU  - Shin,
AU  - J.
AU  - I.
AU  - Cheon,
AU  - K.
AU  - A.
AU  - Solmi,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1017/S2045796023000574
L1  - internal-pdf://0810032056/Kim-2023-Subjective and objective sleep altera.pdf
PY  - 2023
SP  - e48
T2  - Epidemiology &amp; Psychiatric Science
TI  - Subjective and objective sleep alterations in medication-naive children and adolescents with autism spectrum disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37469173
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/E9FFDB56FFF8096B63E7A9850C91BA7A/S2045796023000574a.pdf/div-class-title-subjective-and-objective-sleep-alterations-in-medication-naive-children-and-adolescents-with-autism-spectrum-disorder-a-systematic-review-and-meta-analysis-div.pdf
VL  - 32
ER  -
TY  - JOUR
AB  - **BACKGROUND:**

The coronavirus disease (COVID-19) and universal mitigation strategies have fundamentally affected peoples&#039; lives worldwide, particularly during the first two years of the pandemic. Reductions in physical activity (PA) and increased mental health (MH) problems among children and youth have been observed. This systematic review and meta-analysis investigated the relationship between physical activity (PA) and mental health (MH) among children and youth during the COVID-19 pandemic. 

**METHODS:**

Four electronic databases (EMBASE, PsycINFO, PubMed, and Web of Science) were systematically searched to identify studies that (1) examined the relationship between PA and MH among children and youth (aged 2-24 years old) and (2) were published in peer-reviewed journals in English between January 2020 and December 2021. Relationships between PA and two MH aspects (i.e., negative and positive psychological responses) among children and youth at different age ranges and those with disabilities or chronic conditions (DCC) were synthesized. Meta-analyses were also performed for eligible studies to determine the pooled effect size. 

**RESULTS:**

A total of 58 studies were eventually included for variable categorization, with 32 eligible for meta-analyses. Our synthesis results showed that greater PA participation was strongly related to lower negative psychological responses (i.e., anxiety, depression, stress, insomnia, fatigue, and mental health problems) and higher positive psychological responses (i.e., general well-being and vigor) in children and youth during COVID-19. The pattern and strength of relations between PA and MH outcomes varied across age ranges and health conditions, with preschoolers and those with DCC receiving less attention in the existing research. Meta-analysis results showed that the magnitude of associations of PA with negative (Fisher&#039;s z = - 0.198, p &lt; 0.001) and positive (Fisher&#039;s z = 0.170, p &lt; 0.001) psychological responses among children and youth was weak. These results were linked to age of participants, study quality, and reporting of PA-related information. 

**CONCLUSIONS:**

PA participation and MH among children and youth deteriorated during the COVID-19 pandemic and were closely associated with each other. For the post-COVID-19 era, additional research on age- and health condition-specific relationships between PA and MH outcomes from a comprehensive perspective is warranted. (Word count: 344 words).
AN  - 37468975
AU  - Li,
AU  - B.
AU  - Ng,
AU  - K.
AU  - Tong,
AU  - X.
AU  - Zhou,
AU  - X.
AU  - Ye,
AU  - J.
AU  - Yu,
AU  - J.
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1186/s13034-023-00629-4
L1  - internal-pdf://0197860452/Li-2023-Physical activity and mental health in.pdf
PY  - 2023
SP  - 92
T2  - Child &amp; Adolescent Psychiatry &amp; Mental Health [Electronic Resource]
TI  - Physical activity and mental health in children and youth during COVID-19: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37468975
UR  - https://capmh.biomedcentral.com/counter/pdf/10.1186/s13034-023-00629-4.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - **Background**

Functional Family Therapy (FFT) is a short-term family-based intervention for youth with behaviour problems. FFT has been widely implemented in the USA and other high-income countries. It is often described as an evidence-based program with consistent, positive effects.

**Objectives**

We aimed to synthesise the best available data to assess the effectiveness of FFT for families of youth with behaviour problems.Search MethodsSearches were performed in 2013&ndash;2014 and August 2020. We searched 22 bibliographic databases (including PsycINFO, ERIC, MEDLINE, Science Direct, Sociological Abstracts, Social Services Abstracts, World CAT dissertations and theses, and the Web of Science Core Collection), as well as government policy databanks and professional websites. Reference lists of articles were examined, and experts were contacted to search for missing information.

**Selection Criteria**

We included randomised controlled trials (RCTs) and quasi-experimental designs (QEDs) with parallel cohorts and statistical controls for between-group differences at baseline. Participants were families of young people aged 11&ndash;18 with behaviour problems. FFT programmes were compared with usual services, alternative treatment, and no treatment. There were no publication, geographic, or language restrictions.

**Data Collection and Analysis**

Two reviewers independently screened 1039 titles and abstracts, read all available study reports, assessed study eligibility, and extracted data onto structured electronic forms. We assessed risks of bias (ROB) using modified versions of the Cochrane ROB tool and the What Works Clearinghouse standards. Where possible, we used random effects models with inverse variance weights to pool results across studies. We used odds ratios for dichotomous outcomes and standardised mean differences for continuous outcomes. We used Hedges g to adjust for small sample sizes. We assessed the heterogeneity of effects with
AU  - Littell,
AU  - J.
AU  - H.
AU  - Pigott,
AU  - T.
AU  - D.
AU  - Nilsen,
AU  - K.
AU  - H.
AU  - Roberts,
AU  - J.
AU  - Labrum,
AU  - T.
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/cl2.1324
L1  - internal-pdf://1842224650/Campbell Systematic Reviews - 2023 - Littell.c.pdf
PY  - 2023
T2  - Campbell Systematic Reviews
TI  - Functional Family Therapy for families of youth (age 11&ndash;18) with behaviour problems: A systematic review and meta-analysis
ER  -
TY  - JOUR
AB  - **Objective:**
A new formulation of extended-release methylphenidate (PRC-063) was approved to treat ADHD. This metaanalysis was conducted to study the efficacy and safety of PRC-063 for ADHD. 

**Method:** 
We searched for published trials to October 2022 in several databases. 

**Results:** 
A total of 1,215 patients from 5 RCTs were included. We observed significant improvement for PRC-063 in ADHD Rating Scale (ADHD-RS; MD = &minus;6.73, 95% CI [&minus;10.34, &minus;3.12]) compared with placebo. The effect of PRC-063 on the sleep problems due to ADHD was not statistically different from placebo. Six subscales of Pittsburg Sleep Quality Index (PSQI) showed no statistical significance between PRC-063 and placebo. The result showed no significant difference comparing PRC-063 with placebo in serious treatment-emergent adverse events (TEAEs) (RR = 0.80, 95% CI [0.03, 19.34]). In subgroup analysis according to age, PRC-063 was more efficacious in minors compare to adults. 

**Conclusion:** 
PRC-063 is an efficacious and safe treatment for ADHD, especially in children and adolescents.
AN  - 36794817
AU  - Zhu,
AU  - S.
AU  - Wang,
AU  - T.
AU  - Wang,
AU  - J.
AU  - Yang,
AU  - S.
AU  - Yu,
AU  - Z.
AU  - Gao,
AU  - H.
AU  - Chen,
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/10870547231153941
L1  - internal-pdf://0980490106/10870547231153941.cleaned.pdf
PY  - 2023
SP  - 10870547231153941
T2  - Journal of Attention Disorders
TI  - Efficacy and Safety of PRC-063 for Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-analysis From Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36794817
ER  -
TY  - JOUR
AB  - OBJECTIVE: Trauma exposure in childhood is common and can lead to a range of negative mental health outcomes, including posttraumatic stress disorder (PTSD). In many settings, resources to address this distress are scarce. Group-based interventions require minimal resources and training, can be delivered by non-mental health specialists, and target larger numbers of young people. Our meta-analysis sought to establish whether such an approach is an effective method for targeting PTSD symptoms, and to identify potential moderators of effectiveness. 

METHOD: We searched PubMed, PsycNET and PTSDPubs for randomised controlled trials (RCTs) which used a group-based PTSD intervention, with children aged 6-18 years. Data were extracted for PTSD symptoms and depression symptoms. We conducted a random effects meta-analysis to obtain between group pooled effect size estimates. This study was registered on PROSPERO (CRD42020187214). 

RESULTS: The initial search identified 9,650 studies, of which 42 were eligible for inclusion (N=5,998). Children randomised to a group-based intervention had significantly lower PTSD symptoms post-treatment compared to control, with a medium pooled effect (g=-0.55, CI -0.76, -0.35). Group interventions were superior when compared to either active or passive controls; at follow-up; and for depression symptoms. There was a large amount of heterogeneity, but no evidence that this was explained by whether the intervention was delivered in a low-to-middle income or high-income country, included caregivers, or was universal or targeted. 

CONCLUSION: Group PTSD interventions, particularly CBT-based, are effective at targeting children&#039;s post-trauma distress. There was evidence of effectiveness when delivered in highly complex and resource-scarce settings and to a range of trauma-exposed groups, including those exposed to war/conflict, natural disasters, and abuse.
AN  - 36948393
AU  - Davis,
AU  - R.
AU  - S.
AU  - Meiser-Stedman,
AU  - R.
AU  - Afzal,
AU  - N.
AU  - Devaney,
AU  - J.
AU  - Halligan,
AU  - S.
AU  - L.
AU  - Lofthouse,
AU  - K.
AU  - Smith,
AU  - P.
AU  - Stallard,
AU  - P.
AU  - Ye,
AU  - S.
AU  - Hiller,
AU  - R.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2023.02.013
L1  - internal-pdf://1094884354/Davis.pdf
PY  - 2023
SP  - 20
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Meta-analytic Review: Group-Based Interventions for Treating Posttraumatic Stress Symptoms in Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36948393
VL  - 20
ER  -
TY  - JOUR
AB  - **OBJECTIVE:**

Although front-line doctors recommend medications, this kind of treatment has limited efficacy in improving executive functions (EFs) in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). This study explored the effects of non-pharmacological intervention on EFs in children and adolescents with ADHD. 

**METHODS:**

In accordance with the Preferred Reporting Items for Systematic Review and Meta-analyses guidelines, we searched seven electronic databases: APA PsycINFO, CINAHL Complete, EMBASE, ERIC, Medline, Pubmed, and Web of Science, from inception to March 2022. Two authors independently screened studies for eligibility, extracted data, and assessed bias risk using the Physiotherapy Evidence Database scale. Our analyses included randomized controlled trials and non-randomized comparison studies of non-pharmacological interventions and assessed EFs through neurocognitive tasks in children and adolescents between 5 and 18 years. 

**RESULTS:**

Sixty-seven studies with 3147 participants met the inclusion criteria. The final meta-analysis included 74 independent interventions categorized into six categories: cognitive training, EF-specific curriculum, game-based training, mindfulness practice, neurofeedback training, and physical exercise. Overall, non-pharmacological interventions (combined) produced significant moderate to large effects on overall EFs in children and adolescents with ADHD (g=0.673). Physical exercise had a large positive effect on domain-specific EFs, including inhibitory control (g=0.900) and cognitive flexibility (g=1.377). Cognitive training had a large training effect on working memory (g=0.907), and an EF-specific curriculum had a small to moderate beneficial effect on planning performance (g=0.532). 

**CONCLUSION:**

Non-pharmacological interventions, particularly physical exercise, cognitive training, and an EF-specific curriculum, appear to have beneficial effects on EFs in children and adolescents with ADHD.
AN  - 37450981
AU  - Qiu,
AU  - H.
AU  - Liang,
AU  - X.
AU  - Wang,
AU  - P.
AU  - Zhang,
AU  - H.
AU  - Shum,
AU  - D.
AU  - H.
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.ajp.2023.103692
L1  - internal-pdf://1563436865/Qiu_2023.pdf
PY  - 2023
SP  - 103692
T2  - Asian Journal of Psychiatry
TI  - Efficacy of non-pharmacological interventions on executive functions in children and adolescents with ADHD: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37450981
UR  - https://www.sciencedirect.com/science/article/pii/S1876201823002484?via%3Dihub
VL  - 87
ER  -
TY  - JOUR
AB  - BACKGROUND: With the increasing prevalence of Tourette syndrome (TS), the search for alternative therapy for TS is a growing public concern. In recent years, a growing number of randomized controlled trials have revealed the value of acupuncture combined with herbal medicine for the treatment of TS; however, its holistic efficacy and safety remains unclear. This study aimed to evaluate the efficacy and safety of acupuncture combined with herbal medicine and to provide preliminary evidence for clinical practice.

METHODS: Eight databases were searched from their establishment to November 27, 2022 to collect randomized controlled trials (RCTs) of acupuncture combined with herbal medicine for TS treatment. Two researchers independently completed the study screening, data extraction and risk of bias assessment by using NoteExpress, Excel and Cochrane Risk of Bias Tool 2.0 (RoB 2.0). Stata 15.0 software was applied to conduct meta-analysis.

RESULTS: A total of 1400 participants in 18 RCTs were included. Compared with the Western medicine (WM) , acupuncture combined with herbal medicine had better curative effect in the field of effective rate (RR = 1.18, 95% CI [1.12, 1.23], P &lt; 0.05, I2= 0%), Yale Global Tic Severity Scale (YGTSS) total score (MD = -3.91, 95% CI [-5.49, -2.33], P &lt; 0.05, I2 = 96.4%), TCM syndrome total score (MD = -2.42, 95% CI [-3.71,-1.13], P &lt; 0.05, I2 = 87.1%) and serum IgE negative rate (RR = 3.41, 95% CI [1.69, 6.87], P &lt; 0.05, I2 = 0%). Furthermore, acupuncture combined with herbal medicine reduced the adverse reaction rate (RR = 0.20, 95% CI [0.14,0.30], P &lt; 0.05, I2 = 0%) and the recurrence rate (RR = 0.27, 95% CI [0.13,0.52], P &lt; 0.05, I2 = 0%).

CONCLUSION: This study demonstrated the efficacy and safety of acupuncture combined with herbal medicine, which is probably a better alternative therapy for TS. However, the small number, low quality and potential bias of the included studies caused the limitations of our results. More high-quality RCTs are required to provide supplementary evidence in the future.
AN  - 37844564
AU  - Li,
AU  - J.
AU  - Li,
AU  - C.
AU  - Ma,
AU  - Y.
AU  - Yuan,
AU  - M.
AU  - Liu,
AU  - Y.
DA  - Oct 16
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1159/000534115
DP  - Ovid Technologies
J2  - Complementary Med
L1  - internal-pdf://4103099657/Li-2023-Efficacy and safety of acupuncture com.pdf
LA  - English
M3  - Meta-Analysis
N1  - Li, JiaweiLi, ChuncaiMa, YuqiYuan, MingxingLiu, Yuan
PY  - 2023
SP  - 1
T2  - Complementary Medical Research
TI  - Efficacy and safety of acupuncture combined with herbal medicine for children and adolescents with Tourette syndrome: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37844564
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37844564&amp;id=doi:10.1159%2F000534115&amp;issn=2504-2092&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1&amp;date=2023&amp;title=Complementary+Medical+Research&amp;atitle=Efficacy+and+safety+of+acupuncture+combined+with+herbal+medicine+for+children+and+adolescents+with+Tourette+syndrome%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Li&amp;pid=%3Cauthor%3ELi+J%3C%2Fauthor%3E%3CAN%3E37844564%3C%2FAN%3E%3CDT%3EMeta-Analysis%3C%2FDT%3E
UR  - https://karger.com/cmr/article-pdf/doi/10.1159/000534115/4043831/000534115.pdf
ER  -
TY  - JOUR
AB  - **Background**
Following sexual abuse, children and young people may develop a range of psychological problems, including anxiety, depression, post‐traumatic stress disorder (PTSD), and a range of behaviour problems. Those working with children and young people experiencing these problems may use one or more of a range of psychological approaches.

**Objectives**
To assess the relative effectiveness of psychological interventions compared to other treatments or no treatment controls, to overcome psychological consequences of sexual abuse in children and young people up to 18 years of age.

Secondary objectives

To rank psychotherapies according to their effectiveness.
To compare different &lsquo;doses&rsquo; of the same intervention.

**Search methods**
In November 2022 we searched CENTRAL, MEDLINE, Embase, PsycINFO, 12 other databases and two trials registers. We reviewed the reference lists of included studies, alongside other work in the field, and communicated with the authors of included studies.

**Selection criteria**
We included randomised controlled trials comparing psychological interventions for sexually abused children and young people up to 18 years old with other treatments or no treatments. Interventions included: cognitive behavioural therapy (CBT), psychodynamic therapy, family therapy, child centred therapy (CCT), and eye movement desensitisation and reprocessing (EMDR). We included both individual and group formats.

**Data collection and analysis**
Two review authors independently selected studies, extracted data and assessed the risk of bias for our primary outcomes (psychological distress/mental health, behaviour, social functioning, relationships with family and others) and secondary outcomes (substance misuse, delinquency, resilience, carer distress and efficacy).

We considered the effects of the interventions on all outcomes at post‐treatment, six months follow‐up and 12 months follow‐up. For each outcome and time point with sufficient data, we performed random‐effects network and pairwise meta‐analyses to determine an overall effect estimate for each possible pair of therapies. Where meta‐analysis was not possible, we report the summaries from single studies. Due to the low number of studies in each network, we did not attempt to determine the probabilities of each treatment being the most effective relative to the others for each outcome at each time point.

We rated the certainty of evidence with GRADE for each outcome.

**Main results**
We included 22 studies (1478 participants) in this review. Most of the participants were female (range: 52% to 100%), and were mainly white. Limited information was provided on socioeconomic status of participants. Seventeen studies were conducted in North America, with the remaining studies conducted in the UK (N = 2), Iran (N = 1), Australia (N = 1) and Democratic Republic of Congo (N = 1). CBT was explored in 14 studies and CCT in eight studies; psychodynamic therapy, family therapy and EMDR were each explored in two studies. Management as usual (MAU) was the comparator in three studies and a waiting list was the comparator in five studies. For all outcomes, comparisons were informed by low numbers of studies (one to three per comparison), sample sizes were small (median = 52, range 11 to 229) and networks were poorly connected. Our estimates were all imprecise and uncertain.

Primary outcomes
At post‐treatment, network meta‐analysis (NMA) was possible for measures of psychological distress and behaviour, but not for social functioning. Relative to MAU, there was very low certainty evidence that CCT involving parent and child reduced PTSD (standardised mean difference (SMD) ‐0.87, 95% confidence intervals (CI) ‐1.64 to ‐0.10), and CBT with only the child reduced PTSD symptoms (SMD ‐0.96, 95% CI ‐1.72 to ‐0.20). There was no clear evidence of an effect of any therapy relative to MAU for other primary outcomes or at any other time point.

Secondary outcomes
Compared to MAU, there was very low certainty evidence that, at post‐treatment, CBT delivered to the child and the carer might reduce parents&#039; emotional reactions (SMD ‐6.95, 95% CI ‐10.11 to ‐3.80), and that CCT might reduce parents&#039; stress. However, there is high uncertainty in these effect estimates and both comparisons were informed only by one study. There was no evidence that the other therapies improved any other secondary outcome.

We attributed very low levels of confidence for all NMA and pairwise estimates for the following reasons. Reporting limitations resulted in judgements of &#039;unclear&#039; to &#039;high&#039; risk of bias in relation to selection, detection, performance, attrition and reporting bias; the effect estimates we derived were imprecise, and small or close to no change; our networks were underpowered due to the low number of studies informing them; and whilst studies were broadly comparable with regard to settings, the use of a manual, the training of the therapists, the duration of treatment and number of sessions offered, there was considerable variability in the age of participants and the format in which the interventions were delivered (individual or group).

**Authors&#039; conclusions**
There was weak evidence that both CCT (delivered to child and carer) and CBT (delivered to the child) might reduce PTSD symptoms at post‐treatment. However, the effect estimates are uncertain and imprecise. For the remaining outcomes examined, none of the estimates suggested that any of the interventions reduced symptoms compared to management as usual.

Weaknesses in the evidence base include the dearth of evidence from low‐ and middle‐income countries. Further, not all interventions have been evaluated to the same extent, and there is little evidence regarding the effectiveness of interventions for male participants or those from different ethnicities. In 18 studies, the age ranges of participants ranged from 4 to 16 years old or 5 to 17 years old. This may have influenced the way in which the interventions were delivered, received, and consequently influenced outcomes.

Many of the included studies evaluated interventions that were developed by members of the research team. In others, developers were involved in monitoring the delivery of the treatment. It remains the case that evaluations conducted by independent research teams are needed to reduce the potential for investigator bias.

Studies addressing these gaps would help to establish the relative effectiveness of interventions currently used with this vulnerable population.
AU  - Caro,
AU  - P.
AU  - Turner,
AU  - W.
AU  - Caldwell,
AU  - D.
AU  - M.
AU  - Macdonald,
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD013361.pub2
L1  - internal-pdf://2932526552/Caro_et_al-2023-Cochrane_Database_of_Systemati.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Comparative effectiveness of psychological interventions for treating the psychological consequences of sexual abuse in children and adolescents: a network meta‐analysis
ER  -
TY  - JOUR
AB  - **RATIONALE:** 
Children with neurodevelopmental disorders such as attention-deficit hyperactivity disorder (ADHD), autism, developmental language disorder (DLD), intellectual disability (ID), and social (pragmatic) communication disorder (SPCD) experience difficulties with social functioning due to differences in their social, emotional and cognitive skills. Previous systematic reviews have focussed on specific aspects of social functioning rather than broader peer functioning and friendships. 

**OBJECTIVE:** 
To systematically review and methodologically appraise the quality and effectiveness of existing intervention studies that measured friendship outcomes for children with ADHD, autism, DLD, ID, and SPCD. 

**METHOD:** 
Following PRISMA guidelines, we searched five electronic databases: CINAHL, Embase, Eric, PsycINFO, and PubMed. Two independent researchers screened all abstracts and disagreements were discussed with a third researcher to reach consensus. The methodological quality of studies was assessed using the Cochrane Risk of Bias Tool for Randomised Trials. 

**RESULTS:** 
Twelve studies involving 15 interventions were included. Studies included 683 children with a neurodevelopmental disorder and 190 typically-developing children and diagnosed with either autism or ADHD. Within-group meta-analysis showed that the pooled intervention effects for friendship across all interventions were small to moderate (z = 2.761, p = 0.006, g = 0.485). The pooled intervention effect between intervention and comparison groups was not significant (z = 1.206, p = 0.400, g = 0.215). 

**CONCLUSION:** 
Findings provide evidence that some individual interventions are effective in improving social functioning and fostering more meaningful friendships between children with neurodevelopmental disorders and their peers. Effective interventions involved educators, targeted child characteristics known to moderate peer functioning, actively involved peers, and incorporated techniques to facilitate positive peer perceptions and strategies to support peers. Future research should evaluate the effectiveness of friendship interventions for children with DLD, ID and SPCD, more comprehensively assess peer functioning, include child self-report measures of friendship, and longitudinally evaluate downstream effects on friendship.
AN  - 38096327
AU  - Cordier,
AU  - R.
AU  - Parsons,
AU  - L.
AU  - Wilkes-Gillan,
AU  - S.
AU  - Cook,
AU  - M.
AU  - McCloskey-Martinez,
AU  - M.
AU  - Graham,
AU  - P.
AU  - Littlefair,
AU  - D.
AU  - Kent,
AU  - C.
AU  - Speyer,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0295917
L1  - internal-pdf://2622891239/Cordier-2023-Friendship interventions for chil.pdf
PY  - 2023
SP  - e0295917
T2  - PLoS ONE [Electronic Resource]
TI  - Friendship interventions for children with neurodevelopmental needs: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=38096327
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295917&amp;type=printable
VL  - 18
ER  -
TY  - JOUR
AB  - OBJECTIVES: A systematic review and meta-analysis of studies of single exercise on core symptoms and executive function in adolescents with ADHD. 

METHODS: Four databases were searched for studies of the effects of single exercise on core symptoms and executive functioning in adolescents with ADHD. 

RESULTS: Thirteen studies were included, and a single session of exercise had small effect-size improvements in core symptoms and executive function in adolescents with ADHD: 10 to 13 year olds in the early adolescent-elementary school years and 18 to 24 year olds in the late adolescent-college years. Moderate-intensity continuous training, high-intensity interval training, single sessions of less than 30 minutes, and single sessions of 30 minutes and more significantly improved cycling training, attention, inhibition, substance use, and pre-study abstinence. 

CONCLUSIONS: A single session of exercise had an overall ameliorative effect on core symptoms and executive function in adolescents with ADHD.
AN  - 38156611
AU  - Chen,
AU  - J.
AU  - W.
AU  - Zhu,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/10870547231217321
L1  - internal-pdf://0735539891/chen-zhu-2023-single-exercise-for-core-symptom.pdf
PY  - 2023
SP  - 10870547231217321
T2  - Journal of Attention Disorders
TI  - Single Exercise for Core Symptoms and Executive Functions in ADHD: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38156611
UR  - https://journals.sagepub.com/doi/10.1177/10870547231217321
ER  -
TY  - JOUR
AB  - **Background:**
Promoting school readiness is a vital strategy to close the learning gaps and reach children&#039;s full potential. This systematic review aims to examine the effectiveness of early childhood interventions delivered in educational settings for children with autism and other developmental disabilities aged 3-6 years in improving six developmental outcome domains. 

**Methods:** 
Sensitive searches were conducted in seven international databases and three Chinese regional databases, as well as seven grey literature repositories, for all available studies published in English or Chinese language. All records were double screened. Two bilingual reviewers were involved in extraction and quality appraisal. Effect sizes were synthesised using robust variance estimation. 

**Results:** 
Twenty-eight studies were included in the statistical analyses. Findings provided tentative evidence of social and communication trainings in improving social and communication skills (d = 1.22, 95% CI [0.68, 1.76]) and language interventions in increasing language abilities (d = 0.55, 95% CI [0.33, 0.76]). Treatment effects varied by diagnosis and context. There was substantial heterogeneity across studies. 

**Conclusion:**
We call for intersectional partnerships to promote the inclusion of children with autism and other developmental disabilities in early childhood service and education, as well as more robust research, especially in low- and middle-income countries and involving more types of developmental disabilities.
AN  - WOS:001098332100001
AU  - Fang,
AU  - Z.
AU  - Y.
AU  - Liu,
AU  - X.
AU  - R.
AU  - Zhang,
AU  - C.
AU  - Qiao,
AU  - D.
AU  - P.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1016/j.rasd.2023.102257
L1  - internal-pdf://1300436854/Fang_2023.pdf
PY  - 2023
SP  - 25
T2  - Research in Autism Spectrum Disorders
TI  - Early childhood interventions in educational settings that promote school readiness for children with autism and other developmental disabilities: Systematic review
UR  - &lt;Go to ISI&gt;://WOS:001098332100001
UR  - https://www.sciencedirect.com/science/article/pii/S1750946723001575?via%3Dihub
VL  - 108
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
This systematic review evaluates and summarizes existing eating disorder (ED) prevention programs in Latin American countries. 

**METHODS**
A systematic literature search was conducted using the Cochrane Controlled Trial Register, PubMed, and Virtual Health Library databases up to and including July 31, 2022. All ED prevention studies published in English, Spanish or Portuguese were eligible, regardless of the study design, sample characteristics, and type of prevention programs. The Cochrane Collaboration Risk of Bias criteria were used to evaluate the quality of the included studies. 

**RESULTS**
Twenty-two studies were included. Most were pilot studies that were nonrandomized, had a high risk of bias, were from Mexico and Brazil, and employed selective interventions. Dissonance-based programs and social cognitive theory were the commonly used approaches in interventions, and most of them were tested in adolescent girls and women. Short follow-ups were used, varying from 1 to 6 months. Many found significant decreases after the intervention and/or at follow-up in ED/disordered eating risk behaviors/symptoms, negative affect, body-ideal internalization, and body image disturbances. 

**CONCLUSIONS**
This review highlights promising efforts to prevent EDs among Latin American countries. Some barriers in conducting research include funding restrictions, laws that do not allow remuneration or compensation for participants, and high costs of training. Nonetheless, the outcomes of the programs developed and evaluated so far are positive enough to merit further work on ED prevention. Efforts for future researchers should recruit samples with diverse characteristics, use robust designs and data analysis techniques, and expand the accessibility of prevention programs. 

**PUBLIC SIGNIFICANCE STATEMENT**
The development of effective eating disorder (ED) prevention programs that can be broadly implemented is a public health priority. Nevertheless, there is limited evidence regarding the characteristics of ED prevention programs and their efficacy among Latin American countries. In the present study, we reviewed existing ED prevention programs adopted in Latin America, described their characteristics and outcomes, noted the limitations of available programs, and discussed the implications of these findings for efforts to prevent the development of EDs in Latin America. The outcomes of the programs developed and evaluated so far are positive enough to merit the development and rigorous evaluation of future programs and their broad dissemination in Latin American countries. PROSPERO registration number CRD42021275245.
AN  - 36789735
AU  - Dunker,
AU  - K.
AU  - L.
AU  - L.
AU  - Carvalho,
AU  - P.
AU  - H.
AU  - B.
AU  - Amaral,
AU  - A.
AU  - C.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/eat.23916
L1  - internal-pdf://2164700850/Dunker-2023-Eating disorders prevention progra.pdf
PY  - 2023
SP  - 15
T2  - International Journal of Eating Disorders
TI  - Eating disorders prevention programs in Latin American countries: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36789735
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eat.23916?download=true
VL  - 15
ER  -
TY  - JOUR
AB  - We conducted a network meta-analysis to assess and rank the efficacy of different physical activities on motor function, social function, communication, and stereotyped behavior in children with autism spectrum disorder. PubMed, EBSCO, Cochrane Library, and Web of Science databases were searched through May 25, 2023. A total of 37 studies involving 1200 participants and 17 interventions were included in our study. Based on the ranking probabilities, Tai Chi Chuan and fundamental motor skill intervention were ranked as possibly the most effective intervention for motor function and communication, respectively. Kata techniques had the highest probability of being best for stereotyped behavior and social function. This review provides valuable information that physical activity can be a useful strategy in the management of autism spectrum disorder.
AN  - WOS:001118759200001
AU  - Li,
AU  - Y.
AU  - H.
AU  - Feng,
AU  - Y.
AU  - Q.
AU  - Zhong,
AU  - J.
AU  - G.
AU  - Zou,
AU  - Z.
AU  - Lan,
AU  - W.
AU  - T.
AU  - Shen,
AU  - Y.
AU  - Y.
AU  - Gong,
AU  - J.
AU  - H.
AU  - Zhao,
AU  - B.
AU  - X.
AU  - Tong,
AU  - C.
AU  - Sit,
AU  - C.
AU  - H.
AU  - P.
AU  - Hou,
AU  - X.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40489-023-00418-x
L1  - internal-pdf://2962174893/Li-2023-The Effects of Physical Activity Inter.pdf
PY  - 2023
SP  - 15
T2  - Review Journal of Autism and Developmental Disorders
TI  - The Effects of Physical Activity Interventions in Children with Autism Spectrum Disorder: a Systematic Review and Network Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001118759200001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-023-00418-x.pdf
ER  -
TY  - JOUR
AB  - OBJECTIVE: Children impacted by adversity and trauma often experience psychological, emotional, behavioral, and academic difficulties. To address these concerns, there is a growing call for trauma-informed school systems to better support students with trauma histories. Teacher involvement in trauma-informed approaches is vital but understudied.

METHOD: We conducted a meta-analytic review of the literature published between 1990 and 2019 to evaluate outcomes for teachers and students involved in teacher-delivered trauma interventions. Inclusion criteria specified peer-reviewed studies, dissertations, and nonacademic reports that used randomized controlled and nonrandomized pre-post intervention designs.

RESULTS: We found 20 articles, of which, 12 were pre-post and eight were randomized designs. Seven articles specifically incorporated trauma-informed care (TIC), whereas the other 13 were traditional trauma-based mental health interventions. We conducted meta-analyses to assess student trauma symptom severity and teacher knowledge of trauma-informed practices. Results revealed that after participating in teacher-delivered trauma interventions, students reported significantly reduced trauma symptom severity postintervention and less severity of symptoms than students in the control conditions. There were no differences between trauma-based and TIC intervention student outcomes. Teachers exhibited greater knowledge acquisition after participating in TIC interventions.

CONCLUSION: These findings suggest that trauma interventions, both with and without explicitly referencing TIC principles, are evidence-based in the context of teacher-facilitated school interventions. Additional research is needed to evaluate the organizational benefits of TIC, particularly to determine if the benefits of trauma-informed schools extend beyond students. We conclude with research, policy, and practice recommendations for transformative change to create trauma-informed schools. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
AU  - Cafaro,
AU  - C.
AU  - L.
AU  - Gonzalez
AU  - Molina,
AU  - E.
AU  - Patton,
AU  - E.
AU  - McMahon,
AU  - S.
AU  - D.
AU  - Brown,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/tra0001515
L1  - internal-pdf://1156746975/2023-71161-001.cleaned.pdf
PY  - 2023
T2  - Psychological trauma : theory, research, practice and policy
TI  - Meta-analyses of teacher-delivered trauma-based and trauma-informed care interventions
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37166916
ER  -
TY  - JOUR
AB  - Sibling-mediated interventions (SMI) have the potential to increase social communication, play, and interpersonal skills for children on the autism spectrum. However, less is known about effective practices for training siblings to be intervention mediators. Existing SMI systematic reviews and meta-analyses have focused on the effects of SMIs for children on the autism spectrum. The purpose of this meta-analytic review was to (a) examine the methodological quality of existing single-case experimental design SMI studies based on What Works Clearinghouse standards; and (b) calculate omnibus effects for participants with autism and their siblings. Nineteen studies were located which met standards with or without reservations. Omnibus effect sizes were low for children with autism and moderate for neurotypical siblings.
AN  - WOS:000950126300001
AU  - Bilgili-Karabacak,
AU  - I.
AU  - Duenas,
AU  - A.
AU  - D.
AU  - Settanni,
AU  - E.
AU  - Bauer,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40489-023-00362-w
L1  - internal-pdf://0054722857/Bilgili-Karabac-A Quantitative Systematic Revi.pdf
PY  - 2023
SP  - 17
T2  - Review Journal of Autism and Developmental Disorders
TI  - A Quantitative Systematic Review of Sibling-Mediated Interventions for Young Children with Autism: Effects on Sibling Outcomes
UR  - &lt;Go to ISI&gt;://WOS:000950126300001
UR  - https://link.springer.com/article/10.1007/s40489-023-00362-w
UR  - https://link.springer.com/content/pdf/10.1007/s40489-023-00362-w.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: Anxiety, depression, and stress are the most common mental health problems in childhood. Exercise interventions in childhood help to promote mental health. 

OBJECTIVE: To investigate the relationship between exercise interventions and improvement of negative emotions such as anxiety, depression, and stress in children (5-12 years). 

METHODS: Articles were searched in five electronic databases from their inception to January 2023. The meta-analysis was performed using Stata 16.0. RESULTS: Twenty-three intervention studies included 6830 children. 1) The exercise intervention group was significantly better than the control group in improving negative emotions (Standard Mean Difference SMD=-0.25, 95% Confidence Intervals CI: -0.34 to -0.15, P &lt; 0.01). Exercise intervention improved different kinds of negative emotions: anxiety (SMD=-0.19, 95% CI: -0.33 to -0.06, P &lt; 0.01), depression (SMD=-0.22, 95% CI: -0.43 to -0.01, P &lt; 0.01), and stress (SMD=-0.33, 95% CI: -0.53 to -0.14, P &lt; 0.01); it was most effective at relieving problematic stress. Exercise interventions lasting 20-45 min were most effective in improving children&#039;s negative emotions (SMD=-0.38, 95% CI: -0.56 to -0.20, P &lt; 0.01). An exercise intervention period of 10 weeks was more effective in improving children&#039;s negative mood (SMD=-0.26, 95% CI: -0.34 to -0.17, P = 0.274). 

CONCLUSION: Exercise interventions may improve negative emotions such as anxiety, depression, and stress in children. These findings may have clinical implications for children with negative affect. However, these studies showed a large heterogeneity, and the results should be interpreted with caution. Future studies should report the variability of exercise interventions by gender, age group, and type, intensity, and place of exercise.
AN  - 37608261
AU  - Li,
AU  - J.
AU  - Jiang,
AU  - X.
AU  - Huang,
AU  - Z.
AU  - Shao,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12887-023-04247-z
L1  - internal-pdf://3461452362/Li-2023-Exercise intervention and improvement.pdf
PY  - 2023
SP  - 411
T2  - Bmc Pediatrics
TI  - Exercise intervention and improvement of negative emotions in children: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37608261
UR  - https://bmcpediatr.biomedcentral.com/counter/pdf/10.1186/s12887-023-04247-z.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - **Background**
Substance use is a global issue, with around 30 to 35 million individuals estimated to have a substance‐use disorder. Motivational interviewing (MI) is a client‐centred method that aims to strengthen a person&#039;s motivation and commitment to a specific goal by exploring their reasons for change and resolving ambivalence, in an atmosphere of acceptance and compassion. This review updates the 2011 version by Smedslund and colleagues.

**Objectives**
To assess the effectiveness of motivational interviewing for substance use on the extent of substance use, readiness to change, and retention in treatment.

**Search methods**
We searched 18 electronic databases, six websites, four mailing lists, and the reference lists of included studies and reviews. The last search dates were in February 2021 and November 2022.

**Selection criteria**
We included randomised controlled trials with individuals using drugs, alcohol, or both. Interventions were MI or motivational enhancement therapy (MET), delivered individually and face to face. Eligible control interventions were no intervention, treatment as usual, assessment and feedback, or other active intervention.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane, and assessed the certainty of evidence with GRADE. We conducted meta‐analyses for the three outcomes (extent of substance use, readiness to change, retention in treatment) at four time points (post‐intervention, short‐, medium‐, and long‐term follow‐up).

**Main results**
We included 93 studies with 22,776 participants. MI was delivered in one to nine sessions. Session durations varied, from as little as 10 minutes to as long as 148 minutes per session, across included studies. Study settings included inpatient and outpatient clinics, universities, army recruitment centres, veterans&#039; health centres, and prisons.

We judged 69 studies to be at high risk of bias in at least one domain and 24 studies to be at low or unclear risk.

Comparing MI to no intervention revealed a small to moderate effect of MI in substance use post‐intervention (standardised mean difference (SMD) 0.48, 95% confidence interval (CI) 0.07 to 0.89; I2 = 75%; 6 studies, 471 participants; low‐certainty evidence). The effect was weaker at short‐term follow‐up (SMD 0.20, 95% CI 0.12 to 0.28; 19 studies, 3351 participants; very low‐certainty evidence). This comparison revealed a difference in favour of MI at medium‐term follow‐up (SMD 0.12, 95% CI 0.05 to 0.20; 16 studies, 3137 participants; low‐certainty evidence) and no difference at long‐term follow‐up (SMD 0.12, 95% CI ‐0.00 to 0.25; 9 studies, 1525 participants; very low‐certainty evidence). There was no difference in readiness to change (SMD 0.05, 95% CI ‐0.11 to 0.22; 5 studies, 1495 participants; very low‐certainty evidence). Retention in treatment was slightly higher with MI (SMD 0.26, 95% CI ‐0.00 to 0.52; 2 studies, 427 participants; very low‐certainty evidence).

Comparing MI to treatment as usual revealed a very small negative effect in substance use post‐intervention (SMD ‐0.14, 95% CI ‐0.27 to ‐0.02; 5 studies, 976 participants; very low‐certainty evidence). There was no difference at short‐term follow‐up (SMD 0.07, 95% CI ‐0.03 to 0.17; 14 studies, 3066 participants), a very small benefit of MI at medium‐term follow‐up (SMD 0.12, 95% CI 0.02 to 0.22; 9 studies, 1624 participants), and no difference at long‐term follow‐up (SMD 0.06, 95% CI ‐0.05 to 0.17; 8 studies, 1449 participants), all with low‐certainty evidence. There was no difference in readiness to change (SMD 0.06, 95% CI ‐0.27 to 0.39; 2 studies, 150 participants) and retention in treatment (SMD ‐0.09, 95% CI ‐0.34 to 0.16; 5 studies, 1295 participants), both with very low‐certainty evidence.

Comparing MI to assessment and feedback revealed no difference in substance use at short‐term follow‐up (SMD 0.09, 95% CI ‐0.05 to 0.23; 7 studies, 854 participants; low‐certainty evidence). A small benefit for MI was shown at medium‐term (SMD 0.24, 95% CI 0.08 to 0.40; 6 studies, 688 participants) and long‐term follow‐up (SMD 0.24, 95% CI 0.07 to 0.41; 3 studies, 448 participants), both with moderate‐certainty evidence. None of the studies in this comparison measured substance use at the post‐intervention time point, readiness to change, and retention in treatment.

Comparing MI to another active intervention revealed no difference in substance use at any follow‐up time point, all with low‐certainty evidence: post‐intervention (SMD 0.07, 95% CI ‐0.15 to 0.29; 3 studies, 338 participants); short‐term (SMD 0.05, 95% CI ‐0.03 to 0.13; 18 studies, 2795 participants); medium‐term (SMD 0.08, 95% CI ‐0.01 to 0.17; 15 studies, 2352 participants); and long‐term follow‐up (SMD 0.03, 95% CI ‐0.07 to 0.13; 10 studies, 1908 participants). There was no difference in readiness to change (SMD 0.15, 95% CI ‐0.00 to 0.30; 5 studies, 988 participants; low‐certainty evidence) and retention in treatment (SMD ‐0.04, 95% CI ‐0.23 to 0.14; 12 studies, 1945 participants; moderate‐certainty evidence).

We downgraded the certainty of evidence due to inconsistency, study limitations, publication bias, and imprecision.

**Authors&#039; conclusions**
Motivational interviewing may reduce substance use compared with no intervention up to a short follow‐up period. MI probably reduces substance use slightly compared with assessment and feedback over medium‐ and long‐term periods. MI may make little to no difference to substance use compared to treatment as usual and another active intervention. It is unclear if MI has an effect on readiness to change and retention in treatment. The studies included in this review were heterogeneous in many respects, including the characteristics of participants, substance(s) used, and interventions. Given the widespread use of MI and the many studies examining MI, it is very important that counsellors adhere to and report quality conditions so that only studies in which the intervention implemented was actually MI are included in evidence syntheses and systematic reviews. Overall, we have moderate to no confidence in the evidence, which forces us to be careful about our conclusions. Consequently, future studies are likely to change the findings and conclusions of this review.
AD  - Institute of General Practice and Family Medicine, Center of Health Sciences, Martin Luther University Halle Wittenberg, Halle (Saale), Germany.Department of Preventive Medicine, School of Public Health, Addis Ababa University, Addis Ababa, Ethiopia.Institute for Medical Knowledge Management, Association of the Scientific Medical Societies in Germany, Berlin, c/o Philipps University Marburg, Berlin &amp; Marburg, Germany.Norwegian Institute of Public Health, Oslo, Norway.
AN  - 38084817
AU  - Schwenker,
AU  - R.
AU  - Dietrich,
AU  - C.
AU  - E.
AU  - Hirpa,
AU  - S.
AU  - Nothacker,
AU  - M.
AU  - Smedslund,
AU  - G.
AU  - Frese,
AU  - T.
AU  - Unverzagt,
AU  - S.
DA  - Dec 12
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD008063.pub3
KW  - Humans
KW  - *Motivational Interviewing/methods
KW  - *Substance-Related Disorders/therapy
KW  - Time Factors
KW  - Motivation
KW  - Affect
L1  - internal-pdf://2483306919/Schwenker_et_al-2023-Cochrane_Database_of_Syst.pdf
N1  - Schwenker, RosemarieDietrich, Carla EmiliaHirpa, SelamawitNothacker, MonikaSmedslund, GeirFrese, ThomasUnverzagt, SusanneengReviewSystematic ReviewEnglandCochrane Database Syst Rev. 2023 Dec 12;12(12):CD008063. doi: 10.1002/14651858.CD008063.pub3.
PY  - 2023
SP  - CD008063
T2  - Cochrane Database Syst Rev
TI  - Motivational interviewing for substance use reduction
UR  - https://www.ncbi.nlm.nih.gov/pubmed/38084817
VL  - 12
ER  -
TY  - JOUR
AB  - **Background:**

Currently, melatonin is used to treat children and adolescents with insomnia without knowing the full extent of the short-term and long-term consequences. Our aim was to provide clinicians and guideline panels with a systematic assessment of serious-and non-serious adverse events seen in continuation of melatonin treatment and the impact on pubertal development and bone health following long-term administration in children and adolescents with chronic insomnia. 

**Methods:**

We searched PubMed, Embase, Cinahl and PsycINFO via Ovid, up to March 17, 2023, for studies on melatonin treatment among children and adolescents (aged 5-20 years) with chronic insomnia. The language was restricted to English, Danish, Norwegian, and Swedish. Outcomes were non-serious adverse events and serious adverse events assessed 2-4 weeks after initiating treatment and pubertal development and bone health, with no restriction on definition or time of measurement. Observational studies were included for the assessment of long-term outcomes, and serious and non-serious adverse events were assessed via randomised studies. The certainty of the evidence was assessed using Grades of Recommendation, Assessment, Development and Evaluation (GRADE). The protocol is registered with the Danish Health Authority. 

**Findings:**

We identified 22 randomised studies with 1350 patients reporting on serious-and non-serious adverse events and four observational studies with a total of 105 patients reporting on pubertal development. Melatonin was not associated with serious adverse events, yet the number of patients experiencing non-serious adverse events was increased (Relative risk 1.56, 95% CI 1.01-2.43, 17 studies, I&lt;sup&gt;2&lt;/sup&gt; = 47%). Three studies reported little or no influence on pubertal development following 2-4 years of treatment, whereas one study registered a potential delay following longer treatment durations (&gt;7 years). These findings need further evaluation due to several methodological limitations. 

**Interpretation:**

Children who use melatonin are likely to experience non-serious adverse events, yet the actual extent to which melatonin leads to non-serious adverse events and the long-term consequences remain uncertain. This major gap of knowledge on safety calls for caution against complacent use of melatonin in children and adolescents with chronic insomnia and for more research to inform clinicians and guideline panels on this key issue. Funding: The Danish Health Authority. The Parker Institute, Bispebjerg and Frederiksberg Hospital, supported by the Oak Foundation.
AN  - 37483551
AU  - Handel,
AU  - M.
AU  - N.
AU  - Andersen,
AU  - H.
AU  - K.
AU  - Ussing,
AU  - A.
AU  - Virring,
AU  - A.
AU  - Jennum,
AU  - P.
AU  - Debes,
AU  - N.
AU  - M.
AU  - Laursen,
AU  - T.
AU  - Baandrup,
AU  - L.
AU  - Gade,
AU  - C.
AU  - Dettmann,
AU  - J.
AU  - Holm,
AU  - J.
AU  - Krogh,
AU  - C.
AU  - Birkefoss,
AU  - K.
AU  - Tarp,
AU  - S.
AU  - Bliddal,
AU  - M.
AU  - Edemann-Callesen,
AU  - H.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.eclinm.2023.102083
L1  - internal-pdf://2105350034/Handel-2023-The short-term and long-term adver.pdf
PY  - 2023
SP  - 102083
T2  - EClinicalMedicine
TI  - The short-term and long-term adverse effects of melatonin treatment in children and adolescents: a systematic review and GRADE assessment
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37483551
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359736/pdf/main.pdf
VL  - 61
ER  -
TY  - JOUR
AB  - Gut dysbiosis is associated with sepsis and necrotizing enterocolitis in preterm infants, which can adversely affect long-term growth and neurodevelopment. We aimed to synthesise evidence for the effect of probiotic supplementation on growth and neurodevelopmental outcomes in preterm infants. MEDLINE, EMBASE, EMCARE, Cochrane CENTRAL, and grey literature were searched in February 2022. Only randomized controlled trials (RCTs) were included. Meta-analysis was performed using random effects model. Effect sizes were expressed as standardized mean difference (SMD), mean difference (MD) or risk ratio (RR) and their corresponding 95% confidence intervals (CI). Risk of Bias (ROB) was assessed using the ROB-2 tool. Certainty of Evidence (CoE) was summarized using GRADE guidelines. Thirty RCTs (n = 4817) were included. Meta-analysis showed that probiotic supplementation was associated with better short-term weight gain [SMD 0.24 (95%CI 0.04, 0.44); 22 RCTs (n = 3721); p = 0.02; I&lt;sup&gt;2&lt;/sup&gt; = 88%; CoE: low]. However, length [SMD 0.12 (95%CI -0.13, 0.36); 7 RCTs, (n = 899); p = 0.35; I&lt;sup&gt;2&lt;/sup&gt; = 69%; CoE: low] and head circumference [SMD 0.09 (95%CI -0.15, 0.34); 8 RCTs (n = 1132); p = 0.46; I&lt;sup&gt;2&lt;/sup&gt; = 76%; CoE: low] were similar between the probiotic and placebo groups. Probiotic supplementation had no effect on neurodevelopmental impairment [RR 0.91 (95%CI 0.76, 1.08); 5 RCTs (n = 1556); p = 0.27; I&lt;sup&gt;2&lt;/sup&gt; = 0%; CoE: low]. Probiotic supplementation was associated with better short-term weight gain, but did not affect length, head circumference, long-term growth, and neurodevelopmental outcomes of preterm infants. Adequately powered RCTs are needed in this area. Prospero Registration: CRD42020064992.
AN  - 36788356
AU  - Panchal,
AU  - H.
AU  - Athalye-Jape,
AU  - G.
AU  - Rao,
AU  - S.
AU  - Patole,
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1038/s41430-023-01270-2
L1  - internal-pdf://0837290478/Panchal-2023-Growth and neuro-developmental ou.pdf
PY  - 2023
SP  - 14
T2  - European Journal of Clinical Nutrition
TI  - Growth and neuro-developmental outcomes of probiotic supplemented preterm infants-a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36788356
UR  - https://www.nature.com/articles/s41430-023-01270-2.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Non-suicidal self-injury (NSSI) is the deliberate and self-inflicted damage to body tissue in the absence of fatal intent, and has become a serious health problem among adolescents. The aim of this study was to evaluate the efficacy of treatment for NSSI in this population through a systematic revision and meta-analysis (PROSPERO ID: 252355). Studies with therapies that reduced NSSI were included. The search was performed in the Medline, APA PsycINFO and PubPsych databases. The synthesis of measures for the main outcome (NSSI reduction) and for secondary outcomes (global functioning change and depressive symptomatology reduction) was performed using a random effects model. The search identified a total of 1881 studies. The systematic review included five studies and the meta-analysis four studies. The summary effect estimate for the standardized mean difference in NSSI was -0.53 (95% CI: -0.82, -0.25), in global functioning it was 0.62 (95% CI: 0.34, 0.91), and in depressive symptomatology it was -0.59 (95% CI: -0.82, -0.36). The certainty of the evidence using the GRADE method is low. We conclude that therapies specifically aimed at reducing NSSI are effective in reducing both NSSI and depressive symptoms while increasing global functioning. (c) 2022 Sociedad Espanola de Psiquiatria y Salud Mental (SEPSM). Published by Elsevier Espana, S.L.U. All rights reserved.
AN  - WOS:001126839300001
AU  - Arqueros,
AU  - V.
AU  - P.
AU  - Ib&aacute;&ntilde;ez-Beroiz,
AU  - B.
AU  - Go&ntilde;i-Sarri&eacute;s,
AU  - A.
AU  - Jim&eacute;nez,
AU  - A.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.rpsm.2022.10.001
L1  - internal-pdf://2262854777/1-s2.0-S1888989122001252-main.cleaned (1).pdf
PY  - 2023
SP  - 119-126
T2  - Spanish Journal of Psychiatry and Mental Health
TI  - Efficacy of psychotherapeutic interventions for non-suicidal self-injury in adolescent population: Systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001126839300001
UR  - https://www.sciencedirect.com/science/article/pii/S1888989122001252?via%3Dihub
VL  - 16
ER  -
TY  - JOUR
AB  - **Question** 
We compared the effectiveness of different types of parenting interventions based on an a priori taxonomy, and the impact of waitlists versus treatment as usual (TAU), in reducing child internalising problems.

**Study selection and analysis** 
We conducted a systematic review and network meta-analysis of published and unpublished randomised controlled trials (RCTs) until 1 October 2022 that investigated parenting interventions with children younger than 4 years. Exclusion criteria: studies with children born preterm, with intellectual disabilities, or families receiving support for current abuse, neglect, and substance misuse. We assessed the certainty of evidence using the Confidence in Network Meta-Analysis framework. We used random-effects network meta-analysis to estimate standardised mean differences (SMDs) with 95% credible intervals (CrIs).

**Findings** 
Of 20 520 citations identified, 59 RCTs (18 349 participants) were eligible for the network meta-analysis. Parenting interventions focusing on the dyadic relationship (SMD: -0.26, 95% CrI: -0.43 to -0.08) and those with mixed focus (-0.09, -0.17 to -0.02) were more effective in reducing internalising problems than TAU at the first time point available. All interventions were more effective than waitlist, which increased the risk of internalising problems compared with TAU (0.36, 0.19 to 0.52). All effects attenuated at later follow-ups. Most studies were rated as with &#039;high risk&#039; or &#039;some concerns&#039; using the Risk of Bias Assessment Tool V.2. There was no strong evidence of effect modification by theoretically informed components or modifiers.

**Conclusions** 
We found preliminary evidence that relationship-focused and mixed parenting interventions were effective in reducing child internalising problems, and the waitlist comparator increased internalising problems with implications for waiting times between referral and support. Considering the high risk of bias of most studies included, the findings from this meta-analysis should be interpreted with caution. PROSPERO registration number CRD42020172251.
AN  - WOS:001098817400002
AU  - Costantini,
AU  - I.
AU  - L&oacute;pez-L&oacute;pez,
AU  - J.
AU  - A.
AU  - Caldwell,
AU  - D.
AU  - Campbell,
AU  - A.
AU  - Hadjipanayi,
AU  - V.
AU  - Cantrell,
AU  - S.
AU  - J.
AU  - Thomas,
AU  - T.
AU  - Badmann,
AU  - N.
AU  - Paul,
AU  - E.
AU  - James,
AU  - D.
AU  - M.
AU  - Cordero,
AU  - M.
AU  - Jewell,
AU  - T.
AU  - Evans,
AU  - J.
AU  - Pearson,
AU  - R.
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1136/bmjment-2023-300811
L1  - internal-pdf://3216183909/Costantini-2023-Early parenting interventions.pdf
PY  - 2023
SP  - 10
T2  - Bmj Mental Health
TI  - Early parenting interventions to prevent internalising problems in children and adolescents: a global systematic review and network meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001098817400002
UR  - https://mentalhealth.bmj.com/content/ebmental/26/1/e300811.full.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - Cyberbullying is a new and growing bullying practice that generates more harmful consequences than even traditional bullying. In this situation, the role of education plays a decisive role in the fight against this type of practice. In fact, in recent years there has been a significant increase in the number of educational interventions on cyberbullying. However, the scientific literature shows hardly any conclusive results on the effectiveness of these interventions. Therefore, the aim of this meta-analysis is to analyse the effects that prevention programmes on cyberbullying have on the levels of perpetration among school students. To this end, a search strategy was carried out according to the PICOS framework and PRISMA criteria in five different databases: Web of Science (WoS), SCOPUS, Educational Research Information Centre (ERIC), PubMed, ScienceDirect, SpringerLink and Google Scholar. After searching and applying inclusion/exclusion filters, 9 studies were included in the meta-analysis, covering a total of 17 different interventions conducted between 2015 and 2019. These studies described the application of different intervention programmes to students aged between 10 and 17 years. The findings of this meta-analysis showed that educational prevention programmes could decrease levels of bullying perpetration (SMD = 0.08; 95% CI [0.05, 0.11]; p &lt; 0.00001). Implications for strengthening and expanding cyberbullying prevention programmes in the educational context are discussed. In addition, future research is invited to go beyond the educational setting and consider other variables and factors that extend outside the educational environment and that are equally relevant, as well as to focus new lines of research on the important role of the cyberassistant student as an essential part of this type of situation.
AN  - WOS:000924259900001
AU  - Mula-Falcon,
AU  - J.
AU  - Gonzalez,
AU  - C.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.12795/revistafuentes.2023.21525
L1  - internal-pdf://2914632247/Mula-Falcon-2023-Effectiveness of cyberbullyin.pdf
PY  - 2023
SP  - 1-14
T2  - Revista Fuentes
TI  - Effectiveness of cyberbullying prevention programmes on perpetration levels: a meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000924259900001
VL  - 25
ER  -
TY  - JOUR
AB  - Early-onset depression contributes significantly to the global health burden and has long-term negative effects. This meta-analysis collates and examines the effectiveness of family-based interventions, where family members are involved in the treatment of depression in children and adolescents. 

A literature search was performed up to 8th March 2023. Randomised controlled trials of family-based interventions were included for participants aged 3-18 years with a diagnosis of major depressive disorder or dysthymia, according to the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5; American Psychiatric Association, 2013) or with a score above a cut-off on a standardised self-report depression measure. 

The overall effect size for treatment versus active control was g = 0.22 (95% confidence interval [CI]: -0.05-0.50) (nine studies; 659 participants), and for treatment versus non-active control it was g = 0.46 (95% CI: -0.09-1.01) (four studies; 385 participants). Effect sizes were not statistically significant, and heterogeneity was high, ranging between I&lt;sup&gt;2&lt;/sup&gt; = 64.3-81.1%. Subgroup analysis comparing attachment-based family therapy with family therapy using other theoretical frameworks did not yield a significant difference between the two. The effects of family-based therapies were larger than those in the comparison groups, but family-based therapy did not demonstrate a significant treatment benefit compared to the controls. 

More randomised controlled trials are warranted, considering that evidence for other psychotherapies for depression in children and adolescents, indicates modest effects. Family-based therapy may be an alternative for children and adolescents whose needs are not addressed by these treatments.
AN  - 37409629
AU  - van
AU  - Aswegen,
AU  - T.
AU  - Samartzi,
AU  - E.
AU  - Morris,
AU  - L.
AU  - van
AU  - der
AU  - Spek,
AU  - N.
AU  - de
AU  - Vries,
AU  - R.
AU  - Seedat,
AU  - S.
AU  - van
AU  - Straten,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/ijop.12926
L1  - internal-pdf://3536728638/van Aswegen-2023-Effectiveness of family-based.pdf
PY  - 2023
SP  - 06
T2  - International Journal of Psychology
TI  - Effectiveness of family-based therapy for depressive symptoms in children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37409629
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijop.12926?download=true
VL  - 06
ER  -
TY  - JOUR
AB  - Investigating the mechanisms through which psychotherapy brings about desired change can inform efforts to improve therapies. We applied meta-analytic structural equation modeling (MASEM) to assess putative change mechanisms for cognitive behavioral therapy (CBT) as mediators of youth depression treatment outcome. Then, we tested whether candidate mediators (CMs) showed evidence of treatment-specificity to CBT versus interpersonal psychotherapy (IPT). Literature searches identified 34 randomized trials (27 CBT, 6 IPT, 1 CBT/IPT, 3,868 participants, published 1982-2020) that measured seven CMs: negative cognition, social engagement, family functioning, pleasant activity engagement, problem solving, reframing, or avoidance. We assessed mediational pathways and whether posttreatment CMs mediated treatment effects on posttreatment depression symptoms, covarying pretreatment CMs, and symptoms. Treatment type was tested as a moderator of mediational pathways. Results show that negative cognition (24 trials) and pleasant activities (3 trials) mediated depression symptom outcome in CBT. Social engagement and family functioning showed stronger mediation in IPT (5 and 6 trials) than in CBT (14 and 13 trials). We conclude that negative cognition is a robust mediator of CBT but may not be treatment-specific; pleasant activities may also be a mediator of CBT. However, the lack of treatment or mediation effects involving problem solving and reframing contradicts CBT theory. In contrast, social and family mechanisms appear to be IPT-specific mediators. These conclusions are provisional due to small samples examining IPT and several CMs, limitations in CM measurement (i.e., posttreatment retrospective report), and assumptions of MASEM-and will need to be confirmed when more and better evidence accumulates. (PsycInfo Database Record (c) 2023 APA, all rights reserved) Impact Statement Public Significance Statement-To understand how psychotherapy impacts youth depression, we used a new approach to maximize and evaluate information gained from studies of two prominent therapies published over 3 decades. We found that cognitive behavioral therapy reliably reduced negative thinking-though it is unclear through what process-and in some cases, increased engagement in pleasant activities, with both changes in turn reducing depression symptoms. Interpersonal psychotherapy (IPT) appeared to improve depression via similar pathways to those posited for CBT (reducing negative thinking) as well as different pathways, specifically by improving young people&#039;s interpersonal skills and their peer and family relationships. Because few studies were available for some analyses, and because of limitations in the way the data were collected and analyzed, these findings are tentative and need to be confirmed in the future when more and better quality studies are conducted. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AD  - Ng, Mei Yi: meiyi.ng@fiu.eduNg, Mei Yi: Department of Psychology, Center for Children and Families, Florida International University, 11200 SW 8th Street, AHC-4 Room 457, Miami, FL, US, 33199, meiyi.ng@fiu.eduNg, Mei Yi: Department of Psychology, Harvard University, Cambridge, MA, USDiVasto, Katherine A.: Department of Psychology, Harvard University, Cambridge, MA, USGonzalez, Nazc-a-ru: Department of Psychology, Harvard University, Cambridge, MA, USCootner, Samantha: Department of Psychology, Harvard University, Cambridge, MA, USLipsey, Mark W.: Department of Human and Organizational Development, Vanderbilt University, Nashville, TN, USWeisz, John R.: Department of Psychology, Harvard University, Cambridge, MA, US
AN  - 2024-16890-001
AU  - Ng,
AU  - M.
AU  - Y.
AU  - DiVasto,
AU  - K.
AU  - A.
AU  - Gonzalez,
AU  - N.
AU  - Cootner,
AU  - S.
AU  - Lipsey,
AU  - M.
AU  - W.
AU  - Weisz,
AU  - J.
AU  - R.
DA  - Sep-Oct
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/bul0000395
DP  - Ovid Technologies
KW  - depression
KW  - meta-analysis
KW  - children and adolescents
KW  - cognitive behavioral therapy
KW  - interpersonal psychotherapy
KW  - *Cognitive Behavior Therapy
KW  - *Family
KW  - *Interpersonal Psychotherapy
KW  - *Treatment Outcomes
KW  - *Psychological Engagement
KW  - *Youth Mental Health
KW  - Affective Disorders [3211]
KW  - Cognitive Therapy [3311]
KW  - Human
KW  - Male
KW  - Female Childhood (birth-12 yrs)
KW  - School Age (6-12 yrs)
KW  - Adolescence (13-17 yrs)
L1  - internal-pdf://0201546265/2024-16890-001.cleaned.pdf
LA  - English
M3  - Meta Analysis
N1  - DP - Sep-Oct 2023
PY  - 2023
SP  - 507-548
T2  - Psychological Bulletin
TI  - How do cognitive behavioral therapy and interpersonal psychotherapy improve youth depression? Applying meta-analytic structural equation modeling to three decades of randomized trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2024-16890-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2Fbul0000395&amp;issn=0033-2909&amp;isbn=&amp;volume=149&amp;issue=9-10&amp;spage=507&amp;pages=507-548&amp;date=2023&amp;title=Psychological+Bulletin&amp;atitle=How+do+cognitive+behavioral+therapy+and+interpersonal+psychotherapy+improve+youth+depression%3F+Applying+meta-analytic+structural+equation+modeling+to+three+decades+of+randomized+trials.&amp;aulast=Ng&amp;pid=%3Cauthor%3ENg%2C+Mei+Yi%3C%2Fauthor%3E%3CAN%3E2024-16890-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 149
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis evaluated the effectiveness of telehealth social communication intervention on language skills of children with autism spectrum disorder (ASD). Twenty-one studies were included, among which 17 were single subject experimental design (SSED). Language outcomes were categorized into five linguistic domains (phonology, morphology, syntax, semantics, and pragmatics), and meta-analysis was planned for each domain. Meta-analysis was only performed for pragmatic outcomes, due to the small number of studies that included outcomes in other domains. The results showed significant pre- to post-intervention improvement, thus supporting the use of telehealth social communication intervention to improve pragmatic skills among children with ASD. More diverse measures should be used to target linguistic domains beyond pragmatics. The predominant use of SSED warrants large-scale studies for robust evidence in the future.
AN  - WOS:001100461000001
AU  - Hao,
AU  - Y.
AU  - Du,
AU  - Y.
AU  - Zhang,
AU  - S.
AU  - J.
AU  - Sun,
AU  - L.
AU  - Keene,
AU  - G.
AU  - Ikuta,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40489-023-00411-4
L1  - internal-pdf://1677405149/Hao-2023-Effectiveness of Telehealth Social Co.pdf
PY  - 2023
SP  - 18
T2  - Review Journal of Autism and Developmental Disorders
TI  - Effectiveness of Telehealth Social Communication Intervention on Language Skills Among Children with Autism Spectrum Disorder: a Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001100461000001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-023-00411-4.pdf
ER  -
TY  - JOUR
AB  - **Background:** 
Attention-deficit/hyperactivity disorder (ADHD) is typically treated with stimulant medications, which may lead to several adverse effects. Recent animal studies have shown that caffeine can improve the symptoms of ADHD. This systematic review and meta-analysis sought to evaluate the effect of caffeine on ADHD symptoms in children. 

**Methods:** 
PubMed, Embase, and Cochrane databases were searched for randomized controlled trials comparing caffeine with placebo in children, comparing overall symptoms of ADHD, inattention, hyperactivity, and impulsivity. 

**Results:** 
We included seven RCTs in the systematic review for qualitative assessment, with 104 patients aged 5 to 15 years. Four of these studies (n = 76) were included in the meta-analysis. After qualitative analysis, four studies indicated no improvement in any of the ADHD symptoms compared with placebo. One study showed improvement in ADHD symptoms based on 1 of 5 scales applied. One study indicated significant improvement in general symptoms, inattention, and hyperactivity. One study indicated improvement in sustained attention but a worsening of impulsivity. In contrast, when using a quantitative analysis of the general symptoms of ADHD, the data showed no significant difference when comparing placebo with caffeine (standardized mean difference -0.12; 95% CI -0.44 to 0.20; p = 0.45; I&lt;sup&gt;2&lt;/sup&gt; = 0%). 

**Conclusion:** 
overall, the totality of the evidence suggests no significant benefit of caffeine over placebo in the treatment of children with ADHD.
AN  - 37759905
AU  - Perrotte,
AU  - G.
AU  - Moreira,
AU  - M.
AU  - M.
AU  - G.
AU  - de
AU  - Vargas
AU  - Junior,
AU  - A.
AU  - Teixeira
AU  - Filho,
AU  - A.
AU  - Castaldelli-Maia,
AU  - J.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/brainsci13091304
L1  - internal-pdf://3666159702/Perrotte-2023-Effects of Caffeine on Main Symp.pdf
PY  - 2023
SP  - 11
T2  - Brain Sciences
TI  - Effects of Caffeine on Main Symptoms in Children with ADHD: A Systematic Review and Meta-Analysis of Randomized Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37759905
UR  - https://mdpi-res.com/d_attachment/brainsci/brainsci-13-01304/article_deploy/brainsci-13-01304.pdf?version=1694421687
VL  - 13
ER  -
TY  - JOUR
AB  - OBJECTIVES: This study investigates the impact of various physical activity (PA) types on executive functions (EFs) in children and adolescents. DESIGN: A systematic review and network meta-analysis of randomized clinical trials. 

METHODS: We searched databases such as PubMed, Embase, Cochrane, and Web of Science up to April 2023, including randomized controlled trials involving 6 distinct PA types for healthy children and adolescents. The Cochrane risk of bias tool was used to assess the risk of bias, and a random-effects model in STATA 17.0 was used to calculate standardized mean differences (SMDs) and 95% confidence intervals (CI). 

RESULTS: Ball Games emerged as the most effective modality for improving updating accuracy, securing a SUCRA score of 94.4%, and for reducing inhibition reaction time, with a SUCRA score of 94.8%. Cognitively Engaging Physical Activity led in improving inhibition accuracy with a SUCRA score of 71.7%. Dance excelled in improving update accuracy and reducing shifting reaction time, with SUCRA scores of 86.6% and 99.5%, respectively. 

CONCLUSIONS: PA has a significant benefit in EFs in children and adolescents, however the size of the effect varies by type of PA. Ball Games emerged as the most efficacious modality for enhancing updating accuracy and for expediting inhibition reaction time. Cognitively Engaging Physical Activity proved to be the preeminent strategy for improving inhibition accuracy. Dance was distinguished as the optimal approach for improving updating accuracy and reducing shifting reaction time.
AN  - 38042755
AU  - Wang,
AU  - J.
AU  - Yang,
AU  - Y.
AU  - Li,
AU  - L.
AU  - Yang,
AU  - X.
AU  - Guo,
AU  - X.
AU  - Yuan,
AU  - X.
AU  - Xie,
AU  - T.
AU  - Yang,
AU  - K.
AU  - Zhuang,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jsams.2023.11.006
L1  - internal-pdf://0791562912/1-s2.0-S144024402300484X-main.cleaned.pdf
PY  - 2023
SP  - 22
T2  - Journal of Science &amp; Medicine in Sport
TI  - Comparative efficacy of physical activity types on executive functions in children and adolescents: A network meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=38042755
UR  - https://www.sciencedirect.com/science/article/pii/S144024402300484X?via%3Dihub
VL  - 22
ER  -
TY  - JOUR
AB  - BACKGROUND: Child sexual abuse (CSA) is a type of maltreatment considered a global health problem. CSA is a traumatic experience with important consequences for the victim&#039;s health. It is essential to report the effectiveness of CSA prevention programs to offer society useful tools to combat this abuse.

OBJECTIVE: We aimed to study the effectiveness of CSA prevention programs on the knowledge acquisition based on comparing pre- and post-treatment changes, and also if their effectiveness is related to program-related and methodological variables.

PARTICIPANTS AND SETTINGS: Standardised mean change (with studies that report pre-post program measures) of the effectiveness of CSA prevention programs published between 2014 and 2021 was carried out.

METHODS: The general effectiveness of these programs and whether the results were influenced by program-related variables (the duration, the target population, participants&#039; age, or the type of intervention) or by methodology-related factors (the agent who taught them, the geographical area where they were carried out or the way the programs were evaluated) were analysed. A total of 43 samples analysing knowledge about CSA as a dependent variable were included.

RESULTS: The results reported a combined effect size considered large (d&lt;sub&gt;MR&lt;/sub&gt; = -0.96, 95 % CI [-1.10, -0.82], p &lt; .001). High inter-study heterogeneity was observed in the meta-analysis, although only the geographic area where the studies were conducted appears as a significant moderator.

CONCLUSIONS: In conclusion, the prevention programs included in this analysis significantly improved the participants&#039; knowledge acquisition.
AD  - Ferragut, Marta. Department of Psychobiology and Methodology of Behavioral Sciences, Psychology and Speech Therapy Faculty, University of Malaga, Spain. Electronic address: mferragut@uma.es.Cerezo, M Victoria. Department of Psychobiology and Methodology of Behavioral Sciences, Psychology and Speech Therapy Faculty, University of Malaga, Spain.Ortiz-Tallo, Margarita. Asociacion Con, Ciencia, Escuela de Psicoterapia y Creatividad, Malaga, Spain.Rodriguez-Fernandez, Raquel. Department of Methodology of Behavioral Sciences, Psychology Faculty, Distance Learning National University (UNED), Spain.
AN  - 37804801
AU  - Ferragut,
AU  - M.
AU  - Cerezo,
AU  - M.
AU  - V.
AU  - Ortiz-Tallo,
AU  - M.
AU  - Rodriguez-Fernandez,
AU  - R.
DA  - Oct 05
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.chiabu.2023.106489
DP  - Ovid Technologies
J2  - Child Abuse Negl
L1  - internal-pdf://3398980529/1-s2.0-S0145213423004775-main.cleaned.pdf
LA  - English
M3  - Review
N1  - Ferragut, MartaCerezo, M VictoriaOrtiz-Tallo, MargaritaRodriguez-Fernandez, RaquelS0145-2134(23)00477-5
PY  - 2023
SP  - 106489
T2  - Child Abuse &amp; Neglect
TI  - Effectiveness of child sexual abuse prevention programs on knowledge acquisition: A meta-analytical study
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37804801
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:37804801&amp;id=doi:10.1016%2Fj.chiabu.2023.106489&amp;issn=0145-2134&amp;isbn=&amp;volume=146&amp;issue=&amp;spage=106489&amp;pages=106489&amp;date=2023&amp;title=Child+Abuse+%26+Neglect&amp;atitle=Effectiveness+of+child+sexual+abuse+prevention+programs+on+knowledge+acquisition%3A+A+meta-analytical+study.&amp;aulast=Ferragut&amp;pid=%3Cauthor%3EFerragut+M%3C%2Fauthor%3E%3CAN%3E37804801%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/pii/S0145213423004775?via%3Dihub
VL  - 146
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Cognitive behavioural therapy (CBT) and medication are widely accepted and useful interventions for individuals with depression. However, a gap remains in our current understanding of how CBT directly benefits adolescents with depression. AIMS: The purpose of this study was to examine the short- and long-term effectiveness of CBT only, CBT+Medication, or Medication alone in reducing the duration of major depressive episodes, lessening internalizing and externalizing symptoms and improving global functioning. 

METHODS: 
Data were extracted from 14 unique studies with a total of 35 comparisons. Network meta-analysis was conducted and p-scores, a measure of the extent of certainty that one treatment is better than another, were used to rank treatments. 

RESULTS: 
There was no significant difference between any two treatments for depression, nor internalizing or externalizing symptoms. For global functioning, CBT had significantly greater effect at the longest follow-up than CBT+Medication. CBT+Medication had the highest p-score for depression, short- and long-term effects, and internalizing and externalizing symptoms long-term effects. No indication of publication bias was found. 

CONCLUSIONS: 
Neither modality, CBT nor medication, is superior for treating adolescent depression. However, CBT was superior in improving global functioning, which is essential for meeting developmental goals.
AN  - 36632826
AU  - Dardas,
AU  - L.
AU  - A.
AU  - Xu,
AU  - H.
AU  - Franklin,
AU  - M.
AU  - S.
AU  - Scott,
AU  - J.
AU  - Vance,
AU  - A.
AU  - van
AU  - de
AU  - Water,
AU  - B.
AU  - Pan,
AU  - W.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1017/S1352465822000662
L1  - internal-pdf://2382718212/Dardas-2023-Cognitive behavioural therapy and.pdf
PY  - 2023
SP  - 1-16
T2  - Behavioural &amp; Cognitive Psychotherapy
TI  - Cognitive behavioural therapy and medication for treatment of adolescent depression: a network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36632826
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/FA1AB0C69751807C6B5B5A423CD9D08B/S1352465822000662a.pdf/div-class-title-cognitive-behavioural-therapy-and-medication-for-treatment-of-adolescent-depression-a-network-meta-analysis-div.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: There are now hundreds of systematic reviews on attention deficit hyperactivity disorder (ADHD) of variable quality. To help navigate this literature, we have reviewed systematic reviews on any topic on ADHD. 

METHODS: We searched MEDLINE, PubMed, PsycINFO, Cochrane Library, and Web of Science and performed quality assessment according to the Joanna Briggs Institute Manual for Evidence Synthesis. A total of 231 systematic reviews and meta-analyses met the eligibility criteria. 

RESULTS: The prevalence of ADHD was 7.2% for children and adolescents and 2.5% for adults, though with major uncertainty due to methodological variation in the existing literature. There is evidence for both biological and social risk factors for ADHD, but this evidence is mostly correlational rather than causal due to confounding and reverse causality. There is strong evidence for the efficacy of pharmacological treatment on symptom reduction in the short-term, particularly for stimulants. However, there is limited evidence for the efficacy of pharmacotherapy in mitigating adverse life trajectories such as educational attainment, employment, substance abuse, injuries, suicides, crime, and comorbid mental and somatic conditions. Pharmacotherapy is linked with side effects like disturbed sleep, reduced appetite, and increased blood pressure, but less is known about potential adverse effects after long-term use. Evidence of the efficacy of nonpharmacological treatments is mixed. 

CONCLUSIONS: Despite hundreds of systematic reviews on ADHD, key questions are still unanswered. Evidence gaps remain as to a more accurate prevalence of ADHD, whether documented risk factors are causal, the efficacy of nonpharmacological treatments on any outcomes, and pharmacotherapy in mitigating the adverse outcomes associated with ADHD.
AN  - 37974470
AU  - Chaulagain,
AU  - A.
AU  - Lyhmann,
AU  - I.
AU  - Halmoy,
AU  - A.
AU  - Widding-Havneraas,
AU  - T.
AU  - Nyttingnes,
AU  - O.
AU  - Bjelland,
AU  - I.
AU  - Mykletun,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1192/j.eurpsy.2023.2451
L1  - internal-pdf://3656126952/Chaulagain-2023-A systematic meta-review of sy.pdf
PY  - 2023
SP  - e90
T2  - European Psychiatry: the Journal of the Association of European Psychiatrists
TI  - A systematic meta-review of systematic reviews on attention deficit hyperactivity disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37974470
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/B6059CFF9A2CBED026D9F92442216461/S0924933823024513a.pdf/div-class-title-a-systematic-meta-review-of-systematic-reviews-on-attention-deficit-hyperactivity-disorder-div.pdf
VL  - 66
ER  -
TY  - JOUR
AB  - **Purpose:**

We undertook a systematic review and meta-analysis of intervention research studies focused on strengthening the social information-processing (SIP) skills of children.

**Methods:**

A systematic search and review process was employed to identify, screen, and summarize research on SIP-guided interventions. 

**Results:**

The search recovered 183,184 citations published from 1997 to 2022. After screening, 42 articles were retained for a full-text review. Findings from the 15 studies using more rigorous designs [i.e., 8 individual-level randomized control trials (RCTs), 5 cluster-level RCTs, and 2 quasi-experimental studies with statistical controls for selectivity] suggest that SIP-focused interventions produced statistically significant treatment effects on cognitive skills, with mean effect sizes of 0.35 on encoding, 0.13 on hostile attribution bias, 0.13 on goal formulation, 0.16 on response decision, and-more behaviorally-0.37 on aggressive and disruptive comportment. 

**Conclusions:**

SIP-focused interventions are effective. If widely implemented, they hold the potential to reduce aggressive behavior in childhood.
AN  - WOS:001011459400001
AU  - Peng,
AU  - J.
AU  - Li,
AU  - J.
AU  - Y.
AU  - Li,
AU  - D.
AU  - Y.
AU  - Fang,
AU  - Y.
AU  - H.
AU  - Zhang,
AU  - C.
AU  - Fraser,
AU  - M.
AU  - W.
AU  - Guo,
AU  - S.
AU  - Y.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1177/10497315231182449
L1  - internal-pdf://2597922375/Peng_2023.pdf
PY  - 2023
SP  - 28
T2  - Research on Social Work Practice
TI  - Systematic Review and Meta-Analysis of Interventions to Improve Children&#039;s Social Information-Processing Skills
UR  - &lt;Go to ISI&gt;://WOS:001011459400001
UR  - https://journals.sagepub.com/doi/10.1177/10497315231182449
ER  -
TY  - JOUR
AB  - Parents of adolescents are faced with a variety of challenges related to their children&#039;s behavior and development. Behavioral parent training (BPT) programs may be effective strategies to mitigate adverse childhood experiences (ACEs) and other common behavioral problems in the adolescent period. Adolescence is the period following the onset of puberty and describes the transition from childhood to adulthood. Digital BPTs, including those delivered via the internet, downloaded digital content, text message, tablet, and video call, may present a unique opportunity to reach a broad audience of parents of adolescents by removing barriers to program accessibility (e.g., cost and transportation). We conducted a literature review to synthesize the existing evidence on digital BPTs for parents of adolescents.

 We described the digital BPTs, study designs, and evaluation and feasibility outcomes. A structured literature search identified studies meeting the following criteria for inclusion: (a) published between January 2000 and October 2022, (b) peer-reviewed, (c) available in English language, (d) study included a description of a digital BPT methodological approach, (e) study had to identify at least one parent or child behavioral outcome (e.g., parent-reported communication with their child) or feasibility outcome associated with the digital BPT, and (f) study included parents of adolescents aged 10-18 years. We extracted data on the characteristics of the study and demographic characteristics of participants, digital BPT, and evaluation and feasibility outcomes.

Twenty-eight studies met inclusion criteria. Twenty-two unique digital BPTs were evaluated across the published studies. Thirteen digital BPTs (59.1%) were developed from or grounded by an identified theory. Six digital BPTs were freely accessible by the public, while the remaining 16 were available through study participation or purchase. One digital BPT was specifically tailored to parents of adolescents of a racial/ethnic minority group. Of the 16 studies that reported either parent or adolescent race/ethnicity, 10 consisted of more than 50% White parent or adolescent participants. Twenty-four (88.9%) studies provided evaluation data for the digital BPT. Fourteen studies (63.6%) employed a randomized control trial study design, and the remaining study designs included quasi-experimental (n = 2), mixed methods (n = 1), open trial (n = 3), case study (n = 1), pretest-posttest design (n = 1), and feasibility and acceptability trial (n = 2). All studies reported improvements in at least one parent-reported or adolescent-reported behavioral outcome or feasibility outcomes, with effect sizes (Cohen&#039;s d) ranging from small (e.g., 0.20-0.49) to very large (e.g., &gt; 1.20). 

The findings of this review illustrate that technology may be a valuable way to deliver BPTs to parents of adolescents. However, few digital BPTs were developed for parents of adolescents from racial/ethnic minority groups, and many digital BPTs were not available without cost or participation in a research study. Considerations for future research are discussed.
AN  - WOS:001084779800002
AU  - Morgan,
AU  - M.
AU  - H.
AU  - C.
AU  - Huber-Krum,
AU  - S.
AU  - Willis,
AU  - L.
AU  - A.
AU  - Shortt,
AU  - J.
AU  - W.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1007/s11121-023-01596-0
L1  - internal-pdf://1235099243/Morgan-2023-A Literature Review of Digital Beh.pdf
PY  - 2023
SP  - 20
T2  - Prevention Science
TI  - A Literature Review of Digital Behavioral Parent Training Programs for Parents of Adolescents
UR  - &lt;Go to ISI&gt;://WOS:001084779800002
UR  - https://link.springer.com/content/pdf/10.1007/s11121-023-01596-0.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND AND AIMS: 
This paper aimed to evaluate the use of nonpharmacological interventions for the management of autism spectrum disorder (ASD). The effects of acupuncture and behavioural therapy, two nonpharmalogical interventions, on social function in ASD patients are still controversial. This meta-analysis investigated the impact of these two treatments and compared their effects. 

METHODS: 
Seven electronic databases were systematically searched to identify randomized controlled trials (RCTs) on the use of acupuncture or behavioural therapy for ASD. A meta-analysis was carried out using Review Manager 5.4 software. Continuous data are reported as mean differences (MDs) or standardized mean differences (SMDs) with 95% confidence intervals (CIs). An assessment of methodological quality using the Cochrane risk-of-bias (ROB) tool for trials was carried out. The Grading of Recommendation Assessment, Development, and Evaluation (GRADE) was applied to evaluate the quality (certainty) of evidence for results regarding social function indicators. 

RESULTS: 
Thirty RCTs on acupuncture and 36 on behavioural therapy were included. Compared with the control condition, body acupuncture (SMD: 0.76, 95% CI: [0.52, 1.01]; low certainty), modern acupuncture technology (SMD: 0.84, 95% CI: [0.32, 1.35]; low certainty), cognitive behavioural therapy (SMD: 0.42, 95% CI: [0.26, 0.58]; high certainty), the Denver model (SMD: 0.61, 95% CI: [0.23, 0.99]; moderate certainty) and social skills training (SMD: 0.56, 95% CI: [0.41, 0.71]; moderate certainty) improved social functioning. 

CONCLUSION: 
Behavioural therapies (such as CBT, the Denver model, social skills training), improved the social functioning of patients with ASD in the short and long term, as supported by high- and moderate-quality evidence. Acupuncture (including scalp acupuncture, body acupuncture and use of modern acupuncture technology) also improved social functioning, as supported by low- and very low-quality evidence. More high-quality evidence is needed to confirm the effect of acupoint catgut embedding and Early Intensive Behavioural Intervention (EIBI).
AN  - 37725597
AU  - Yu,
AU  - Z.
AU  - Zhang,
AU  - P.
AU  - Tao,
AU  - C.
AU  - Lu,
AU  - L.
AU  - Tang,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0291720
L1  - internal-pdf://1094878539/Yu-2023-Efficacy of nonpharmacological interve.pdf
PY  - 2023
SP  - e0291720
T2  - PLoS ONE [Electronic Resource]
TI  - Efficacy of nonpharmacological interventions targeting social function in children and adults with autism spectrum disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37725597
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0291720&amp;type=printable
VL  - 18
ER  -
TY  - JOUR
AB  - **Background:** 
Interpersonal Psychotherapy-Adolescent Skills Training (IPT-AST) is a standardized depression prevention program for adolescents conducted in campus settings. The purpose of this review is to examine the randomized controlled trials of IPT-AST for the prevention of adolescent depression in the past 20 years. 

**Methods:** 
A systematic search of relevant electronic databases (PubMed, WOS, Embase, PsycINFO, the Cochrane Library, CNKI and WANFANG DATA) and study reference lists was conducted. Any study investigating the effectiveness of IPT-AST in 12- to 20-year-olds with depressive symptoms was eligible. Synthesis was via narrative summary and meta-analysis. 

**Results:** 
A total of 6 studies met the inclusion criteria. Meta-analysis results showed a remarkable improvement in patients&#039; depressive symptoms after IPT-AST intervention (WMD = -5.05, 95% CI = -8.11 to -1.98, p &lt; 0.05, I&lt;sup&gt;2&lt;/sup&gt; = 77%). Six month follow-up data showed that the intervention outcomes of IPT-AST remained significant (WMD = -3.09, 95% CI: -5.23 to -0.94, p &lt; 0.05, I&lt;sup&gt;2&lt;/sup&gt; = 57%). 

**Conclusion:** 
This meta-analysis showed that IPT-AST was effective in adolescents with depressive symptoms at post-prevention and at 6-month follow-up. However, these conclusions are cautious, as they are based on a small number of studies and the presence of author duplication. Future studies should use multi-center, large-sample randomized controlled trials to evaluate the efficacy of IPT-AST for preventing depression in adolescents. Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42023393047.
AN  - 37588027
AU  - Zheng,
AU  - K.
AU  - Xu,
AU  - H.
AU  - Qu,
AU  - C.
AU  - Sun,
AU  - X.
AU  - Xu,
AU  - N.
AU  - Sun,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2023.1147864
L1  - internal-pdf://3507337234/Zheng_2023.pdf
PY  - 2023
SP  - 1147864
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - The effectiveness of Interpersonal Psychotherapy-Adolescent Skills Training for adolescents with depression: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37588027
VL  - 14
ER  -
TY  - JOUR
AB  - **BACKGROUND:**

The purpose of this systematic review is to synthesize the existing literature reporting the effects of computerized cognitive trainings on the executive functions of children with ADHD. 

**METHOD:**

A systematic review was carried out following the PRISMA statement; the primary sources used were five electronic databases (Scopus, Science Direct, Pubmed, Springer, Taylor &amp; Francis). 

**RESULTS:**

20 articles met the eligibility criteria, data on the training characteristics and the effects on executive functions were extracted, followed by an analysis of bias and the methodological quality of the studies. The results of the studies were widely heterogeneous, largely associated with the variety of training programs and the measurement instruments used. The most studied executive functions were working memory and inhibitory control. Some of the studies reported that the intervention led to significant effects on working memory and attention (N = 7), and improvements in inhibitory control (N = 5) and planning (N = 4) were also reported. At the same time, others did not report the effects of the intervention on these processes. The assessment of the quality of the evidence showed important risk biases among the reviewed studies. 

**CONCLUSION:**

Some training based on computer systems showed positive effects on the executive functions of working memory, attention, and inhibitory control in children with ADHD. However, other training sessions did not show significant effects. In general, the evidence shows mixed results, a high diversity of measurement instruments, and high risks of bias between the studies. Therefore, the evidence has not been consistent about the general benefits of computerized training on the executive functions of children with ADHD.
AN  - 37477014
AU  - Robledo-Castro,
AU  - C.
AU  - Lerma-Castano,
AU  - P.
AU  - R.
AU  - Bonilla-Santos,
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/10870547231187164
L1  - internal-pdf://4255853603/Robledo_2023.pdf
PY  - 2023
SP  - 10870547231187164
T2  - Journal of Attention Disorders
TI  - Effect of Cognitive Training Programs Based on Computer Systems on Executive Functions in Children With ADHD: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37477014
UR  - https://journals.sagepub.com/doi/10.1177/10870547231187164
ER  -
TY  - JOUR
AB  - AIMS AND OBJECTIVES: Evidence suggests that preparing patients for surgery using nonpharmacological strategies reduces their anxiety. However, there is no consensus on what the best practices are. This study aims to answer the question: Are interventions using nonpharmacological therapies effective in reducing preoperative anxiety?

BACKGROUND: Preoperative anxiety causes physiological and psychological adverse effects, with a negative effect on postoperative recovery., 

INTRODUCTION: According to the World Health Organization, between 266 and 360 million surgical procedures are performed annually worldwide, and it is estimated that more than 50% of patients will experience some degree of preoperative anxiety.

DESIGN: Systematic review of systematic reviews with results of interventions aimed at mitigating preoperative anxiety.

METHODS: A search was conducted for systematic reviews with meta-analyses published between 2012 and 2021 in Medline, Scopus, Web of Science and Cochrane Library. Quality was assessed using the AMSTAR-2 scale. The protocol was registered in PROSPERO.

RESULTS: A total of 1016 studies were examined, of which 17 systematic reviews were selected, yielding 188 controlled trials with 16,884 participants. In adults, the most common intervention included music, followed by massage, in children virtual reality and clowns. Almost all controlled trials reported a reduction in preoperative anxiety after the intervention, of which almost half had statistically significant results., CONCLUSION: Interventions that include music, massage and virtual reality reduce preoperative anxiety and have shown that they are cost-effective, minimally invasive and with a low risk of adverse effects. Preoperative anxiety can be reduced through a short-term intervention involving nursing professionals as an alternative or complement to drugs.

RELEVANCE TO CLINICAL PRACTICE: This review suggests that nursing professionals, in collaboration with other health professionals, should continue to conduct research on the reduction in preoperative anxiety. Further research in this area is needed, to reduce heterogeneity and consolidate the results.

NO PATIENT OR PUBLIC CONTRIBUTION: Not applied to our study, as it is a systematic review of systematic reviews. 
Copyright &copy; 2023 The Authors. Journal of Clinical Nursing published by John Wiley &amp; Sons Ltd.
AU  - Aguero-Millan,
AU  - B.
AU  - Abajas-Bustillo,
AU  - R.
AU  - Ortego-Mate,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jocn.16755
L1  - internal-pdf://1637582966/Aguero-Millan-2023-Efficacy of nonpharmacologi.pdf
PY  - 2023
T2  - Journal of Clinical Nursing
TI  - Efficacy of nonpharmacologic interventions in preoperative anxiety: A systematic review of systematic reviews
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=reference&amp;D=medp&amp;NEWS=N&amp;AN=37149743
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jocn.16755?download=true
ER  -
TY  - JOUR
AB  - Neuro-developmental delay (NDD) is when a child&#039;s reflexes and nervous system are underdeveloped or immature at a given stage of child development. Neurodevelopmental delays account for delayed skill development surrounding speech, social, emotional, behavioral, motor, and cognitive delays. NDD might affect the child&#039;s psychological and physical well-being, resulting in chronic disease and disabilities throughout adulthood. This review sought to investigate the implication of early diagnosis and intervention of NDD in children. In this regard, this research opted for a systematic meta-analysis that used keywords and Boolean operators to search through main databases, including the Web of Science, JStor, PsychINFO, Science Direct, Cochrane, Scopus, and ASSIA. The result identified that telehealth interventions improved the management of NDD in children. Also, the Early Start Denver Model (ESDM) model was determined to improve the quality of life for NDD children. Another model was LEAP (Learning Experience and Alternative Program for Preschoolers and Their Parents) and Leap (Learning, engaging, and Playing), which improved behavioral, education, and social interventions in NDD children. The study identified that technology could revolutionize NDD interventions in children, possibly improving the quality of life. The parent-children relationship was shown to enhance the management of this condition; thus, it is recommended as one of the best ways to intervene in the management of NDD. Most importantly, the integration of machine learning algorithms and technology can create models; while this may not be significant in the treatment of childhood NDD but instead might be ideal in improving the quality of life for NDD children. Moreover, their social and communication skills along with academic achievements will improve. The study proposes further research in order to understand the different types of NDDs and their intervention strategies to help the researchers identify the most accurate models to improve the conditions and support the parents and guardians in the management.
AN  - 37303321
AU  - Aldharman,
AU  - S.
AU  - S.
AU  - Al-Jabr,
AU  - K.
AU  - H.
AU  - Alharbi,
AU  - Y.
AU  - S.
AU  - Alnajar,
AU  - N.
AU  - K.
AU  - Alkhanani,
AU  - J.
AU  - J.
AU  - Alghamdi,
AU  - A.
AU  - Abdellatif,
AU  - R.
AU  - A.
AU  - Allouzi,
AU  - A.
AU  - Almallah,
AU  - A.
AU  - M.
AU  - Jamil,
AU  - S.
AU  - F.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.7759/cureus.38745
L1  - internal-pdf://0248040217/Aldharman-2023-Implications of Early Diagnosis.pdf
PY  - 2023
SP  - e38745
T2  - Cureus
TI  - Implications of Early Diagnosis and Intervention in the Management of Neurodevelopmental Delay (NDD) in Children: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37303321
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248310/pdf/cureus-0015-00000038745.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Most family violence research has been conducted in high-income countries, although family violence rates are higher in low- and middle-income countries (LMICs), and outcomes more severe. Given the strong associations of family violence with substance use and mental illness, the aim of this systematic review was to examine interventions that targeted familial violence and at least one other condition of substance use or mental illness to determine effective treatments in LMICs. 

We conducted a systematic review of interventions that addressed family violence and mental illness or substance use. A committee of three researchers independently screened titles and abstracts and conducted full-text eligibility assessments. Two researchers conducted a risk of bias assessment. Data were extracted using a structured spreadsheet and narratively synthesized. 

Our search identified 29 articles produced from 19 studies conducted in 13 LMICs. Most (n = 15) studies randomized to study condition. Lack of blinding was the most common threat. The external validity of studies was generally poor. Fourteen studies had a primary intervention target of family violence, mental health, substance use, economic improvement, or HIV. None of the studies showed improvements in all intervention areas. Child maltreatment was less likely to be addressed than intimate partner violence (IPV). Targeted interventions for substance and mental health mostly improved primary outcomes, although they were less effective in reducing IPV. 

Evidence-based treatments must be rigorously evaluated before innovations in implementation can occur. Interventions overwhelmingly addressed IPV victimization and should consider how to work with couples and include men and children.
AN  - 38024805
AU  - Mootz,
AU  - J.
AU  - J.
AU  - Fennig,
AU  - M.
AU  - Giusto,
AU  - A.
AU  - Mumey,
AU  - A.
AU  - Greene,
AU  - C.
AU  - M.
AU  - Wainberg,
AU  - M.
AU  - L.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1017/gmh.2023.62
L1  - internal-pdf://3068730862/Mootz-2023-Interventions addressing family vio.pdf
PY  - 2023
SP  - e71
T2  - Global Mental Health
TI  - Interventions addressing family violence and mental illness or substance use in low- and middle-income countries: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=38024805
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643256/pdf/S2054425123000626a.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **Background**
The prevalence of e‐cigarette use has increased globally amongst children and adolescents in recent years. In response to the increasing prevalence and emerging evidence about the potential harms of e‐cigarettes in children and adolescents, leading public health organisations have called for approaches to address increasing e‐cigarette use. Whilst evaluations of approaches to reduce uptake and use regularly appear in the literature, the collective long‐term benefit of these is currently unclear.

**Objectives**
The co‐primary objectives of the review were to: (1) evaluate the effectiveness of interventions to prevent e‐cigarette use in children and adolescents (aged 19 years and younger) with no prior use, relative to no intervention, waitlist control, usual practice, or an alternative intervention; and (2) evaluate the effectiveness of interventions to cease e‐cigarette use in children and adolescents (aged 19 years and younger) reporting current use, relative to no intervention, waitlist control, usual practice, or an alternative intervention. Secondary objectives were to: (1) examine the effect of such interventions on child and adolescent use of other tobacco products (e.g. cigarettes, cigars types, and chewing tobacco); and (2) describe the unintended adverse effects of the intervention on individuals (e.g. physical or mental health of individuals), or on organisations (e.g. intervention displacement of key curricula or learning opportunities for school students) where such interventions are being implemented.

**Search methods**
We searched CENTRAL, Ovid MEDLINE, Ovid Embase, Ovid PsycINFO, EBSCO CINAHL, and Clarivate Web of Science Core Collection from inception to 1 May 2023. Additionally, we searched two trial registry platforms (WHO International Clinical Trials Registry Platform; US National Institutes of Health Ongoing Trials Register ClinicalTrials.gov), Google Scholar, and the reference lists of relevant systematic reviews. We contacted corresponding authors of articles identified as ongoing studies.

**Selection criteria**
We included randomised controlled trials (RCTs), including cluster‐RCTs, factorial RCTs, and stepped‐wedge RCTs. To be eligible, the primary targets of the interventions must have been children and adolescents aged 19 years or younger. Interventions could have been conducted in any setting, including community, school, health services, or the home, and must have sought to influence children or adolescent (or both) e‐cigarette use directly. Studies with a comparator of no intervention (i.e. control), waitlist control, usual practice, or an alternative intervention not targeting e‐cigarette use were eligible. We included measures to assess the effectiveness of interventions to: prevent child and adolescent e‐cigarette use (including measures of e‐cigarette use amongst those who were never‐users); and cease e‐cigarette use (including measures of e‐cigarette use amongst children and adolescents who were e‐cigarette current‐users). Measures of e‐cigarette use included current‐use (defined as use in the past 30 days) and ever‐use (defined as any lifetime use).

**Data collection and analysis**
Two review authors independently screened the titles and abstracts of references, with any discrepancies resolved through consensus. Pairs of review authors independently assessed the full‐text articles for inclusion in the review. We planned for two review authors to independently extract information from the included studies and assess risk of bias using the Cochrane RoB 2 tool. We planned to conduct multiple meta‐analyses using a random‐effects model to align with the co‐primary objectives of the review. First, we planned to pool interventions to prevent child and adolescent e‐cigarette use and conduct two analyses using the outcome measures of &#039;ever‐use&#039; and &#039;current‐use&#039;. Second, we planned to pool interventions to cease child and adolescent e‐cigarette use and conduct one analysis using the outcome measure of &#039;current‐use&#039;. Where data were unsuitable for pooling in meta‐analyses, we planned to conduct a narrative synthesis using vote‐counting approaches and to follow the Cochrane Handbook for Systematic Reviews of Interventions and the Synthesis Without Meta‐analysis (SWiM) guidelines.

**Main results**
The search of electronic databases identified 7141 citations, with a further 287 records identified from the search of trial registries and Google Scholar. Of the 110 studies (116 records) evaluated in full text, we considered 88 to be ineligible for inclusion for the following reasons: inappropriate outcome (27 studies); intervention (12 studies); study design (31 studies); and participants (18 studies). The remaining 22 studies (28 records) were identified as ongoing studies that may be eligible for inclusion in a future review update. We identified no studies with published data that were eligible for inclusion in the review.

**Authors&#039; conclusions**
We identified no RCTs that met the inclusion criteria for the review, and as such, there is no evidence available from RCTs to assess the potential impact of interventions targeting children and adolescent e‐cigarette use, tobacco use, or any unintended adverse effects. Evidence from studies employing other trial designs (e.g. non‐randomised) may exist; however, such studies were not eligible for inclusion in the review. Evidence from studies using non‐randomised designs should be examined to guide actions to prevent or cease e‐cigarette use.

This is a living systematic review. We search for new evidence every month and update the review when we identify relevant new evidence. Please refer to the Cochrane Database of Systematic Reviews for the current status of this review.
AU  - Barnes,
AU  - C.
AU  - Turon,
AU  - H.
AU  - McCrabb,
AU  - S.
AU  - Hodder,
AU  - R.
AU  - K.
AU  - Yoong,
AU  - S.
AU  - L.
AU  - Stockings,
AU  - E.
AU  - Hall,
AU  - A.
AU  - E.
AU  - Bialek,
AU  - C.
AU  - Morrison,
AU  - J.
AU  - L.
AU  - Wolfenden,
AU  - L.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD015511.pub2
L1  - internal-pdf://2900037651/Barnes_et_al-2023-Cochrane_Database_of_Systema.pdf
PY  - 2023
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions to prevent or cease electronic cigarette use in children and adolescents
ER  -
TY  - JOUR
AB  - Social Anxiety Disorder (SAD) is a very common disorder in childhood and adolescence. Many studies have examined various types of Cognitive Behavioral Therapy (CBT), meaning there is a need for a study exploring the efficacy of CBT. The objectives of this study are to determine what treatments and factors can improve treatment outcomes for SAD. We performed an umbrella review of the effectiveness of psychological interventions in treating SAD in children and adolescents. Nine databases were searched using a combination of keywords. Risk of bias was assessed using AMSTAR-2. Six systematic reviews and meta-analysis were selected and reported. All of those studies assessed the efficacy of CBT in children and adolescents with SAD, demonstrating its short- and long-term effectiveness. The components that seem to be most effective are exposure in any modality and social skills training. Other considerations to take into account are addressed in the discussion.
AN  - WOS:000975493000004
AU  - Diaz-Castela,
AU  - M.
AU  - D.
AU  - Muela-Martinez,
AU  - J.
AU  - A.
AU  - Garcia-Lopez,
AU  - L.
AU  - J.
AU  - Espinosa-Fernandez,
AU  - L.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.21134/rpcna.2023.10.1.2
L1  - internal-pdf://0069062573/Diaz-Castela-2023-The state of psychological t.pdf
PY  - 2023
SP  - 20-30
T2  - Revista De Psicologia Clinica Con Ninos Y Adolescentes
TI  - The state of psychological treatments for social anxiety disorder in children and adolescents: An Umbrella Review
UR  - &lt;Go to ISI&gt;://WOS:000975493000004
VL  - 10
ER  -
TY  - JOUR
AB  - In this paper, systematic review and meta-analysis were used to demonstrate the effectiveness of physical activity intervention on core symptoms of autism spectrum disorder (ASD). Physical activity intervention for core symptoms of ASD were retrieved by computer from the PubMed Cochrane Library, Web of Science, APA PsycNet, and CNKI database during December 1, 2022. Two researchers evaluated the quality of the included literature and extracted the data. Sixteen studies were eventually included, with a total of 587 patients with ASD. Meta-analysis showed that the core symptoms of ASD patients decreased after physical activity intervention, ES(g) = 0.681(95% CI: 0.380-0.982, p = 0.000), specifically, physical activity improved the reduction of social disorder ES(g) = 0.749(95% CI: 0.524-0.973) and repeated rigid behavior ES(g) = 0.553 (95% CI: -0.079 to 1.186). Subgroup analysis showed that preschool children with ASD who were 3-6 years old, exercised for more than 12 weeks, more than 3 times a week, and exercised for more than 90 min per session had better improvement in core symptoms after participating in physical activity. The conclusion of this paper is that physical activity intervention can improve the core symptoms of ASD, especially the reduction of social disorders and repetitive behaviors.
AN  - 37539450
AU  - Wang,
AU  - S.
AU  - Chen,
AU  - D.
AU  - Yang,
AU  - Y.
AU  - Zhu,
AU  - L.
AU  - Xiong,
AU  - X.
AU  - Chen,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/aur.3004
L1  - internal-pdf://0782479832/Wang-2023-Effectiveness of physical activity i.pdf
PY  - 2023
SP  - 04
T2  - Autism research : Official Journal of the International Society for Autism Research
TI  - Effectiveness of physical activity interventions for core symptoms of autism spectrum disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37539450
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aur.3004?download=true
VL  - 04
ER  -
TY  - JOUR
AB  - **AIM:** 
This study aimed to evaluate the effectiveness of melatonin in treating insomnia in children with autism spectrum disorder (ASD). 

**METHODS:** 
Comprehensive searches were conducted in the PubMed, EMBASE, and Web of Science databases from their inception to April 20, 2022. Data were extracted and assessed for quality by two researchers. Statistical analysis was performed using the Stata 15.0 software. 

**RESULTS:** 
Four studies including 238 patients were included. The results showed that compared with the control group, melatonin could shorten the sleep-onset latency (standardized mean difference [SMD] = - 1.34, 95% CI: -2.19 to -0.48), reduce the number of awakenings (SMD = -2.35, 95% CI: -4.62 to -0.08), and prolong the total sleep time (SMD = 1.42, 95% CI: 0.5-2.33) in children with ASD. 

**CONCLUSION:** 
Melatonin has a certain effect on relieving sleep disturbances in children with ASD, which can shorten sleep latency, reduce the number of awakenings, and prolong total sleep time. Larger studies are required to verify this hypothesis.
AN  - 36827993
AU  - Xiong,
AU  - M.
AU  - Li,
AU  - F.
AU  - Liu,
AU  - Z.
AU  - Xie,
AU  - X.
AU  - Shen,
AU  - H.
AU  - Li,
AU  - W.
AU  - Wei,
AU  - L.
AU  - He,
AU  - R.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1055/s-0043-1761437
L1  - internal-pdf://0984946039/Xiong-2023-Efficacy of Melatonin for Insomnia.pdf
PY  - 2023
SP  - 24
T2  - Neuropediatrics
TI  - Efficacy of Melatonin for Insomnia in Children with Autism Spectrum Disorder: A Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36827993
UR  - https://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0043-1761437.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - **INTRODUCTION**
Children exposed to parental intimate partner violence and abuse, mental illness, and substance use experience a range of problems which may persist into adulthood. These risks often co-occur and interact with structural factors such as poverty. Despite increasing evidence, it remains unclear how best to improve outcomes for children and families experiencing these adversities and address the complex issues they face. 

**AIMS AND METHODS**
Systematic review of systematic reviews. We searched international literature databases for systematic reviews, from inception to 2021, to provide an evidence overview of the range and effectiveness of interventions to support children and families where these parental risk factors had been identified. 

**RESULTS**
Sixty-two systematic reviews were included. The majority (n = 59) focused on interventions designed to address single risk factors. Reviews mostly focused on parental mental health (n = 38) and included psychological interventions or parenting-training for mothers. Only two reviews assessed interventions to address all three risk factors in combination and assessed structural interventions. Evidence indicates that families affected by parental mental health problems may be best served by integrated interventions combining therapeutic interventions for parents with parent skills training. Upstream interventions such as income supplementation and welfare reform were demonstrated to reduce the impacts of family adversity. 

**CONCLUSION**
Most intervention approaches focus on mitigating individual psychological harms and seek to address risk factors in isolation, which presents potentially significant gaps in intervention evidence. These interventions may not address the cumulative impacts of co-occurring risks, or social factors that may compound adversities.
AN  - 36789663
AU  - Barrett,
AU  - S.
AU  - Muir,
AU  - C.
AU  - Burns,
AU  - S.
AU  - Adjei,
AU  - N.
AU  - Forman,
AU  - J.
AU  - Hackett,
AU  - S.
AU  - Hirve,
AU  - R.
AU  - Kaner,
AU  - E.
AU  - Lynch,
AU  - R.
AU  - Taylor-Robinson,
AU  - D.
AU  - Wolfe,
AU  - I.
AU  - McGovern,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/15248380231153867
L1  - internal-pdf://2965156163/15248380231153867.cleaned.pdf
PY  - 2023
SP  - 15248380231153867
T2  - Trauma Violence &amp; Abuse
TI  - Interventions to Reduce Parental Substance Use, Domestic Violence and Mental Health Problems, and Their Impacts Upon Children&#039;s Well-Being: A Systematic Review of Reviews and Evidence Mapping
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36789663
ER  -
TY  - JOUR
AB  - This article presents a comprehensive meta-analysis of international studies on the effects of parent training programs (PTP) on antisocial behavior (ASB) in children and adolescents. From systematic literature searches of 7219 reports, we finally selected 239 eligible reports with 241 independent studies and 279 comparisons between a program and a control condition up to the publication year 2020. Although most interventions were based on a cognitive-behavioral approach, we also found a great variety of programs and applications. Overall, the mean effect for PTP was positive for parent/family and ASB outcomes (d = 0.46 and d = 0.47, respectively using the random effect model at postintervention). We also found higher effects on more proximal parental outcomes such as parental stress, parental competencies, and parent-child interaction/relation. However, more distal outcomes such as marital satisfaction or parent psychopathology revealed lower effect sizes. In addition, the link between changes in parental/family outcomes and changes in ASB was significant across several outcome types, thus confirming the general causal assumption of PTP. Postintervention effects were stable across several moderators, although clinical applications revealed slightly higher effect sizes than preventive applications. Several findings cast some doubt on these generally positive results: For example, effect sizes decreased considerably in not only short- (3 to 12 months) but also especially long-term follow ups (12 months or more), and the vast majority of outcome assessments stemmed from parent ratings. Finally, we found a clear negative connection between sample and effect size. Whether this is due to publication bias or indicates a better implementation quality in smaller studies remains an open question. Copyright &copy; 2022 The Authors
AN  - 2020963204
AU  - Beelmann,
AU  - A.
AU  - Arnold,
AU  - L.
AU  - S.
AU  - Hercher,
AU  - J.
DB  - Alerts 6_2022.enl
DO  - /10.1016/j.avb.2022.101798
L1  - internal-pdf://1686486606/Beelmann_2023.pdf
PY  - 2023
T2  - Aggression and Violent Behavior
TI  - Parent training programs for preventing and treating antisocial behavior in children and adolescents: A comprehensive meta-analysis of international studies
UR  - https://www.elsevier.com/locate/aggviobeh
VL  - 68 (no pagination)
ER  -
TY  - JOUR
AB  - Both self-harm and suicidal behaviors have been targeted through school-based prevention programs, many of which have been developed in the United States. The aims of this systematic review were to assess effects of school-based prevention programs on suicide and self-harm and to evaluate whether they are fit to the exporting culture. The review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Our inclusion criteria, structured according to population/problem, intervention, control/comparison, outome, were: children and youth up to 19 years of age, school-based programs at universal, selective or indicated levels compared with teaching as usual or with other programs, and outcomes of suicide or self-harm measured at least 10 weeks after intervention. Studies without a control group or using non-behavioral outcomes were excluded. A comprehensive and systematic literature search was conducted from the 1990s to March 2022. Risk for bias was assessed with checklists adapted from the Cochrane Risk of Bias (ROB) tool. A total of 1,801 abstracts were retrieved. Five studies fulfilled our inclusion criteria, but one had high risk for bias. Confidence in the evidence for effect was assessed with Grading of Recommendations Assessment, Development and Evaluation (GRADE). Studies included in this review were evaluated with respect to applicability in the context of international export. Only two school-based programs demonstrated efficacy in preventing suicidal behaviors. Although implementation of evidence-based interventions is a crucial next step, further replication with simultaneous attention to dissemination and implementation issues are called for. Funding and registration: conducted on assignment by the Swedish government. The protocol is available at the SBU website in Swedish.
AN  - 37366058
AU  - Liljedahl,
AU  - S.
AU  - I.
AU  - Hellner,
AU  - C.
AU  - Pettersson,
AU  - A.
AU  - Ghaderi,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/sjop.12945
L1  - internal-pdf://0471849329/Liljedahl-2023-School-based self-harm preventi.pdf
PY  - 2023
SP  - 27
T2  - Scandinavian Journal of Psychology
TI  - School-based self-harm prevention programs: A systematic review with implications for international implementation
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37366058
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/sjop.12945?download=true
VL  - 27
ER  -
TY  - JOUR
AB  - After-school programmes (ASPs) often provide youth with a safer alternative to unstructured time while providing a context for building skills and forging positive relationships with programme staff and peers. ASPs may be particularly effective for youth with marginalized identities, including youth of colour and youth from low-income backgrounds. Despite this promise, few rigorous evaluations of ASPs have been conducted and even fewer meta-analyses have investigated the effects of ASPs among youth with marginalized identities. 

Using a multi-level meta-analysis of 615 effect sizes across 56 studies (overall n = 128,538), the current study examined the overall effects of ASPs on internalizing, externalizing, school-related, social functioning, and self-perception/identity outcomes among kindergarten through 12th grade youth with marginalized identities. 

Results indicated ASPs to have a small, yet significant positive overall effect on youth outcomes (g = 0.2049, p = .001, 95% CI = 0.08-0.33). Moderator analyses revealed significant differences in effects based on outcome source and outcome measure type. 

Given the ubiquity of ASPs and the challenges that youth experiencing marginalization face, this study uniquely adds to the existing literature and outlines important implications and recommendations for research, policy, and practice. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-45087-001
AU  - Christensen,
AU  - K.
AU  - M.
AU  - Kremer,
AU  - K.
AU  - P.
AU  - Poon,
AU  - C.
AU  - Y.
AU  - Rhodes,
AU  - J.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/casp.2681
L1  - internal-pdf://1571337406/Christensen-2023-A meta-analysis of the effect.pdf
PY  - 2023
SP  - No Pagination Specified
T2  - Journal of Community &amp; Applied Social Psychology
TI  - A meta-analysis of the effects of after-school programmes among youth with marginalized identities
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc19&amp;AN=2023-45087-001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/casp.2681?download=true
ER  -
TY  - JOUR
AB  - BACKGROUND: 
The ability to communicate is integral to all human relationships. Previous research has specifically highlighted communication within families as both a risk and protective factor for anxiety disorders and/or depression. Yet, there is limited understanding about whether communication is amenable to intervention in the context of adolescent psychopathology, and whether doing so improves outcomes. 

AIMS:
The aim of this systematic review was to determine in which contexts and for whom does addressing communication in families appear to work, not work and why? METHOD: We pre-registered our systematic review with PROSPERO (identifier CRD42022298719), followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidance and assessed study quality with the Risk of Bias 2 tool. 

RESULTS: 
Seven randomised controlled trials were identified from a systematic search of the literature. There was significant heterogeneity in the features of communication that were measured across these studies. There were mixed findings regarding whether family-focused interventions led to improvements in communication. Although there was limited evidence that family-focused interventions led to improvements in communication relative to interventions without a family-focused component, we discuss these findings in the context of the significant limitations in the studies reviewed. 

CONCLUSIONS: 
We conclude that further research is required to assess the efficacy of family-focused interventions for improving communication in the context of anxiety and depression in those aged 14-24 years.
AN  - 37641851
AU  - Lloyd,
AU  - A.
AU  - Broadbent,
AU  - A.
AU  - Brooks,
AU  - E.
AU  - Bulsara,
AU  - K.
AU  - Donoghue,
AU  - K.
AU  - Saijaf,
AU  - R.
AU  - Sampson,
AU  - K.
AU  - N.
AU  - Thomson,
AU  - A.
AU  - Fearon,
AU  - P.
AU  - Lawrence,
AU  - P.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/bjo.2023.545
L1  - internal-pdf://1417125097/Lloyd-2023-The impact of family interventions.pdf
PY  - 2023
SP  - e161
T2  - Bjpsych Open
TI  - The impact of family interventions on communication in the context of anxiety and depression in those aged 14-24 years: systematic review of randomised control trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37641851
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/EF8048B6113909C9334209F586AC50DB/S2056472423005458a.pdf/div-class-title-the-impact-of-family-interventions-on-communication-in-the-context-of-anxiety-and-depression-in-those-aged-14-24-years-systematic-review-of-randomised-control-trials-div.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - Dialectical behavior therapy (DBT) is an evidence-based intervention that aims to reduce maladaptive behavior by facilitating development of emotion regulation, with support for use with diagnostically diverse adolescents. We conducted a meta-analysis evaluating change in externalizing symptoms among adolescents in DBT-based interventions across 17 studies (with 25 data points). Results indicate that interventions have a small-to-medium effect in reducing externalizing symptoms (Hedge&#039;s g = -0.499, 95% CI [-0.683, -0.315], p &lt; .001). Greater intervention duration was associated with greater decrease in symptoms (slope = -0.014, Z = -2.312, SE = 0.006, p = .021), though this finding was no longer significant following removal of an outlier. No other moderators were significant (ps range: .182-.862). Findings provide meaningful information about the utility of DBT-based interventions for externalizing problems as currently delivered among adolescents.
AN  - WOS:000995119800001
AU  - Jakubovic,
AU  - R.
AU  - J.
AU  - Drabick,
AU  - D.
AU  - A.
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1037/cps0000140
L1  - internal-pdf://3820672690/Dialectic.pdf
PY  - 2023
SP  - 14
T2  - Clinical Psychology-Science and Practice
TI  - Dialectical Behavior Therapy-Based Interventions for Externalizing Problems Among Adolescents: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000995119800001
ER  -
TY  - JOUR
AB  - **BACKGROUND**
This study aimed to identify targeted interventions for the prevention and treatment of harmful alcohol use. Umbrella review methodology was used to summarise the effectiveness across a broad range of interventions, in order to identify which interventions should be considered for inclusion within universal health coverage schemes in low- and middle-income countries. 

**METHODS AND FINDINGS**
We included systematic reviews with meta-analysis of randomised controlled trials (RCTs) on targeted interventions addressing alcohol use in harmful drinkers or individuals with alcohol use disorder. We only included outcomes related to alcohol consumption, heavy drinking, binge drinking, abstinence, or alcohol-attributable accident, injury, morbidity or mortality. PubMed, Embase, PsycINFO, Cochrane Database of Systematic Reviews, and the International HTA Database were searched from inception to 3 September 2021. Risk of bias of reviews was assessed using the AMSTAR2 tool. After reviewing the abstracts of 9,167 articles, results were summarised narratively and certainty in the body of evidence for each intervention was assessed using GRADE. In total, 86 studies met the inclusion criteria, of which the majority reported outcomes for brief intervention (30 studies) or pharmacological interventions (29 studies). Overall, methodological quality of included studies was low. 

**CONCLUSIONS** For harmful drinking, brief interventions, cognitive behavioural therapy, and motivational interviewing showed a small effect, whereas mentoring in adolescents and children may have a significant long-term effect. For alcohol use disorder, social network approaches and acamprosate showed evidence of a significant and durable effect. More evidence is required on the effectiveness of gamma-hydroxybutyric acid (GHB), nalmefene, and quetiapine, as well as optimal combinations of pharmacological and psychosocial interventions. As an umbrella review, we were unable to identify the extent to which variation between studies stemmed from differences in intervention delivery or variation between country contexts. Further research is required on applicability of findings across settings and best practice for implementation. Funded by the Thai Health Promotion Foundation, grant number 61-00-1812.
AN  - 36823618
AU  - Botwright,
AU  - S.
AU  - Sutawong,
AU  - J.
AU  - Kingkaew,
AU  - P.
AU  - Anothaisintawee,
AU  - T.
AU  - Dabak,
AU  - S.
AU  - V.
AU  - Suwanpanich,
AU  - C.
AU  - Promchit,
AU  - N.
AU  - Kampang,
AU  - R.
AU  - Isaranuwatchai,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12889-023-15152-6
L1  - internal-pdf://1027781119/Botwright-2023-Which interventions for alcohol.pdf
PY  - 2023
SP  - 382
T2  - Bmc Public Health
TI  - Which interventions for alcohol use should be included in a universal healthcare benefit package? An umbrella review of targeted interventions to address harmful drinking and dependence
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36823618
UR  - https://bmcpublichealth.biomedcentral.com/counter/pdf/10.1186/s12889-023-15152-6.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - The efficacy of trauma-focused treatments for children and adolescents is well researched. However, less is known about the long-term and caregiver-reported effects. Searched databases were PsychInfo, MEDLINE, Cochrane Library, PTSDPubs, PubMed, Web of Science, and OpenGrey. Treatment effects of trauma-focused cognitive behavioral therapy (TF-CBT) were computed at 12-month follow-up with posttraumatic stress symptoms (PTSS) as primary outcome and symptoms of depression, anxiety, and grief as secondary outcomes. Concordance between participant and caregiver ratings were investigated. TF-CBT showed large improvements across all outcomes from pre-treatment to 12-month follow-up (PTSS: g = 1.71, CI 1.27-2.15) and favorable results compared to active treatments and treatment as usual at 12-month follow-up (PTSS: g = .35, CI .13-.56). More pronounced effects were found in group settings. No significant differences were detected between participant and caregiver ratings with high reliability across almost all outcomes and assessment points. TF-CBT is a reliable treatment for pediatric PTSS and secondary symptoms with stable results at 12-month follow-up.
AN  - 36959760
AU  - Thielemann,
AU  - J.
AU  - F.
AU  - B.
AU  - Kasparik,
AU  - B.
AU  - Konig,
AU  - J.
AU  - Unterhitzenberger,
AU  - J.
AU  - Rosner,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/10775595231167383
L1  - internal-pdf://3501248186/Thielemann.pdf
PY  - 2023
SP  - 10775595231167383
T2  - Child Maltreatment
TI  - Stability of Treatment Effects and Caregiver-Reported Outcomes: A meta-Analysis of Trauma-Focused Cognitive Behavioral Therapy for Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36959760
ER  -
TY  - JOUR
AB  - **Background**

Class size reductions in general education are some of the most researched educational interventions in social science, yet researchers have not reached any final conclusions regarding their effects. While research on the relationship between general education class size and student achievement is plentiful, research on class size in special education is scarce, even though class size issues must be considered particularly important to students with special educational needs. These students compose a highly diverse group in terms of diagnoses, functional levels, and support needs, but they share a common need for special educational accommodations, which often entails additional instructional support in smaller units than what is normally provided in general education. At this point, there is however a lack of clarity as to the effects of special education class sizes on student academic achievement and socioemotional development. Inevitably, such lack of clarity is an obstacle for special educators and policymakers trying to make informed decisions. This highlights the policy relevance of the current systematic review, in which we sought to examine the effects of small class sizes in special education on the academic achievement, socioemotional development, and well-being of children with special educational needs.

**Objectives**

The objective of this systematic review was to uncover and synthesise data from studies to assess the impact of small class sizes on the academic achievement, socioemotional development, and well-being of students with special educational needs. We also aimed to investigate the extent to which the effects differed among subgroups of students. Finally, we planned to perform a qualitative exploration of the experiences of children, teachers, and parents with class size issues in special education.

**Search Methods**

Relevant studies were identified through electronic searches in bibliographic databases, searches in grey literature resources, searches using Internet search engines, hand-searches of specific targeted journals, and citation-tracking. The following bibliographic databases were searched in April 2021: ERIC (EBSCO-host), Academic Search Premier (EBSCO-host), EconLit (EBSCO-host), APA PsycINFO (EBSCO-host), SocINDEX (EBSCO-host), International Bibliography of the Social Sciences (ProQuest), Sociological Abstracts (ProQuest), and Web of Science (Clarivate, Science Citation Index Expanded &amp; Social Sciences Citation Index). EBSCO OPEN Dissertations was also searched in April 2021, while the remaining searches for grey literature, hand-searches in key journals, and citation-tracking took place between January and May 2022.

**Selection Criteria**

The intervention in this review was a small special education class size. Eligible quantitative study designs were studies that used a well-defined control or comparison group, that is, studies where there was a comparison between students in smaller classes and students in larger classes. Children with special educational needs in grades K-12 (or the equivalent in European countries) in special education were eligible. In addition to exploring the effects of small class sizes in special education from a quantitative perspective, we aimed to gain insight into the lived experiences of children, teachers, and parents with class size issues in special education contexts, as they are presented in the qualitative research literature. The review therefore also included all types of empirical qualitative studies that collected primary data and provided descriptions of main methodological issues such as selection of informants, data collection procedures, and type of data analysis. Eligible qualitative study designs included but were not limited to studies using ethnographic observation or field work formats, or qualitative interview techniques applied to individual or focus group conversations.

**Data Collection and Analysis**

The literature search yielded a total of 26,141 records which were screened for eligibility based on title and abstract. From these, 262 potentially relevant records were retrieved and screened in full text, resulting in seven studies being included: three quantitative and five qualitative studies (one study contained both eligible quantitative and qualitative data). Two of the quantitative studies could not be used in the data synthesis as they were judged to have a critical risk of bias and, in accordance with the protocol, were excluded from the meta-analysis on the basis that they would be more likely to mislead than inform. The third quantitative study did not provide enough information enabling us to calculate an effect size and standard error. Meta-analysis was therefore not possible. Following quality appraisal of the qualitative studies, three qualitative studies were judged to be of sufficient methodological quality. It was not possible to perform a qualitative thematic synthesis since in two of these studies, findings particular to special education class size were scarce. Therefore, only descriptive data extraction could be performed.

**Main Results**

Despite the comprehensive searches, the present review only included seven studies published between 1926 and 2020. Two studies were purely quantitative (Forness, 1985; Metzner, 1926) and from the U.S. Four studies used qualitative methodology (Gottlieb, 1997; Huang, 2020; Keith, 1993; Prunty, 2012) and were from the US (2), China (1), and Ireland (1). One study, MAGI Educational Services (1995), contained both eligible quantitative and qualitative data and was from the U.S.

**Authors&#039; Conclusions**

The major finding of the present review was that there were virtually no contemporary quantitative studies exploring the effects of small class sizes in special education, thus making it impossible to perform a meta-analysis. More research is therefore thoroughly needed. Findings from the summary of included qualitative studies reflected that to the special education students and staff members participating in these studies, smaller class sizes were the preferred option because they allowed for more individualised instruction time and increased teacher attention to students&#039; diverse needs. It should be noted that these studies were few in number and took place in very diverse contexts and across a large time span. There is a need for more qualitative research into the views and experiences of teachers, parents, and school administrators with special education class sizes in different local contexts and across various provision models. But most importantly, future research should strive to represent the voices of children and young people with special needs since they are the experts when it comes to matters concerning their own lives.
AU  - Bondebjerg,
AU  - A.
AU  - Dalgaard,
AU  - N.
AU  - T.
AU  - Filges,
AU  - T.
AU  - Viinholt,
AU  - B.
AU  - C.
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/cl2.1345
L1  - internal-pdf://2729511929/Campbell Systematic Reviews - 2023 - Bondebjer.pdf
PY  - 2023
T2  - Campbell Systematic Reviews
TI  - The effects of small class sizes on students&#039; academic achievement, socioemotional development and well-being in special education: A systematic review
ER  -
TY  - JOUR
AB  - BACKGROUND: Many studies display promising results for interventions that are based on Applied Behavior Analysis (ABA) in the treatment of autism spectrum disorder (ASD). 

METHODS: This meta-analysis assessed the effects of such treatments on developmental outcomes in children with ASD and on parental stress based on 11 studies with 632 participants. 

RESULTS: Compared to treatment as usual, minimal or no treatment, comprehensive ABA-based interventions showed medium effects for intellectual functioning (standardized mean difference SMD = 0.51, 95% CI [0.09; 0.92]) and adaptive behavior (SMD = 0.37, 95% CI [0.03; 0.70]). Language abilities, symptom severity or parental stress did not improve beyond the improvement in control groups. Moderator analyses indicate that language abilities at intake could influence the effect sizes and the influence of treatment intensity might decrease with older age. 

CONCLUSIONS: Practical implications and limitations are discussed.
AN  - 36864429
AU  - Eckes,
AU  - T.
AU  - Buhlmann,
AU  - U.
AU  - Holling,
AU  - H.
AU  - D.
AU  - Mollmann,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12888-022-04412-1
L1  - internal-pdf://1478664436/Eckes-2023-Comprehensive ABA-based interventio.pdf
PY  - 2023
SP  - 133
T2  - Bmc Psychiatry
TI  - Comprehensive ABA-based interventions in the treatment of children with autism spectrum disorder - a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36864429
UR  - https://bmcpsychiatry.biomedcentral.com/counter/pdf/10.1186/s12888-022-04412-1.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - OBJECTIVE: Physical activity (PA) interventions are part of many interdisciplinary programs for the management of children and adolescents with or without physical or psychological conditions or disabilities. Aiming to summarize the available evidence, we conducted an umbrella review of meta-analyses of PA interventions that included psychosocial outcomes in populations of children and adolescents. 

METHOD: Literature searches were conducted in PubMed, Cochrane Central, Web of Science, Medline, SportDiscus, and PsychInfo from Jan 1, 2010 to May 6, 2022. Meta-analyses of randomised and quasi-randomised studies investigating the efficacy of PA interventions for psychosocial outcomes in children and adolescents were included. Summary effects were recalculated using common metric and random-effects models. We assessed between-study heterogeneity, predictive intervals, publication bias, small-study effects, and whether the results of the observed positive studies were more than expected due to the chance. On the basis of these calculations, strength of associations was assessed using quantitative umbrella review criteria, and credibility of evidence using the GRADE approach. Quality was assessed using the AMSTAR-II tool. This study is registered with the Open Science Framework, https://osf.io/ap8qu. 

RESULTS: A total of 112 studies from 18 meta-analyses generating 12 new meta-analyses with 21232 children and adolescents with conditions or disabilities as ADHD, cancer, cerebral palsy, chronic respiratory diseases, depression, neuromotor impairment, obesity and in general populations were included. PA interventions were efficacious in reducing psychological symptoms in all meta-analyses across the different population groups using random-effects models. However, umbrella review criteria suggested a weak strength of association for this outcome, and GRADE credibility of evidence ranged from moderate to very low. For psychological wellbeing, three out of five meta-analyses identified significant effects, but the strength of these associations was weak, and GRADE credibility of evidence ranged from moderate to very low. Similarly, for social outcomes, meta-analyses reported a significant summary effect, but the strength of association was weak, and GRADE credibility of evidence ranged from moderate to very low. For self-esteem, one meta-analysis in children with obesity failed to show any effect. 

CONCLUSION: Even though existing meta-analyses suggested a beneficial effect of PA interventions on psychosocial outcomes across different population groups, the strength of associations was weak, and the credibility of evidence was variable, depending on the target population, outcome, and condition or disability. Randomised studies of PA interventions in children and adolescents with and without different physical and psychological conditions or disabilities should always include psychosocial outcomes as an important dimension of social and mental health.
AN  - 37331468
AU  - Purgato,
AU  - M.
AU  - Cadorin,
AU  - C.
AU  - Prina,
AU  - E.
AU  - Ferreira,
AU  - M.
AU  - C.
AU  - Del
AU  - Piccolo,
AU  - L.
AU  - Gerber,
AU  - M.
AU  - Jordans,
AU  - M.
AU  - J.
AU  - Ostuzzi,
AU  - G.
AU  - Richards,
AU  - J.
AU  - Rudi,
AU  - D.
AU  - Vitali,
AU  - F.
AU  - Cortese,
AU  - S.
AU  - Schena,
AU  - F.
AU  - Barbui,
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jaac.2023.04.017
L1  - internal-pdf://4175814445/Purgato_2023.pdf
PY  - 2023
SP  - 16
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Umbrella Systematic Review and Meta-Analysis: Physical Activity as an Effective Therapeutic Strategy for Improving Psychosocial Outcomes in Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37331468
UR  - https://www.jaacap.org/article/S0890-8567(23)00314-3/fulltext
VL  - 16
ER  -
TY  - JOUR
AB  - Introduction: Documented use and investigation of hypnosis spans centuries and its therapeutic use has received endorsement by multiple medical associations. We conducted a comprehensive overview of meta-analyses examining the efficacy of hypnosis to provide a foundational understanding of hypnosis in evidence-based healthcare, insight into the safety of hypnosis interventions, and identification of gaps in the current research literature. Methods: In our systematic review, meta-analyses of randomized controlled trials on the efficacy of hypnosis in patients with mental or somatic health problems compared to any control condition published after the year 2000 were included. A comprehensive literature search using Medline, Scopus, PsycINFO, The Cochrane Library, HTA Database, Web of Science and a manual search was conducted to identify eligible reviews. Methodological quality of the included meta-analyses was rated using the AMSTAR 2 tool. Effect estimates on various outcomes including at least three comparisons (k &gt;= 3) were extracted and transformed into a common effect size metric (Cohen&#039;s d). If available, information on the certainty of evidence for these outcomes (GRADE assessment) was obtained. Results: We included 49 meta-analyses with 261 distinct primary studies. Most robust evidence was reported for hypnosis in patients undergoing medical procedures (12 reviews, 79 distinct primary studies) and in patients with pain (4 reviews, 65 primary studies). There was a considerable overlap of the primary studies across the meta-analyses. Only nine meta-analyses were rated to have high methodological quality. Reported effect sizes comparing hypnosis against control conditions ranged from d = -0.04 to d = 2.72. Of the reported effects, 25.4% were medium (d &gt;= 0.5), and 28.8% were large (d &gt;= 0.8). Discussion: Our findings underline the potential of hypnosis to positively impact various mental and somatic treatment outcomes, with the largest effects found in patients experiencing pain, patients undergoing medical procedures, and in populations of children/adolescents. Future research should focus on the investigation of moderators of efficacy, on comparing hypnosis to established interventions, on the efficacy of hypnosis for children and adolescents, and on identifying patients who do not benefit from hypnosis. Clinical Trial Registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023395514, identifier CRD42023395514.
AN  - 38268815
AU  - Rosendahl,
AU  - J.
AU  - Alldredge,
AU  - C.
AU  - T.
AU  - Haddenhorst,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.3389/fpsyg.2023.1330238
L1  - internal-pdf://2900190231/Rosendahl-2023-Meta-analytic evidence on the e.pdf
PY  - 2023
SP  - 1330238
T2  - Frontiers in Psychology
TI  - Meta-analytic evidence on the efficacy of hypnosis for mental and somatic health issues: a 20 year perspective
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=38268815
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807512/pdf/fpsyg-14-1330238.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - BACKGROUND: Social anxiety disorder (SAD) is prevalent among children and adolescents. Cognitive-behavioural therapy (CBT) has been used as the first-line treatment. However, evaluation of CBT conducted in a school setting has been scarce. 

OBJECTIVES: This study aims to review the CBT and its effectiveness in the school setting for children and adolescents with SAD or social anxiety symptoms. Quality assessment on individual studies was conducted. 

METHODS: Studies were identified through the search in PsycINFO, ERIC, PubMed and Medline targeting CBT conducted in a school setting with an aim to treat children and adolescents with SAD or social anxiety symptoms. Randomised controlled trials and quasi-experimental studies were selected. 

RESULTS: A total of 7 studies met the inclusion criteria. Five studies were randomised controlled trials, and two were quasi-experimental studies with 2558 participants aged 6-16 years from 138 primary schools and 20 secondary schools. There were minor effects to reduce social anxiety symptoms for children and adolescents at post-intervention in 86% of the selected studies. Friend for Life (FRIENDS), Super Skills for Life (SSL) and Skills for Academic and Social Success (SASS) conducted in school were more effective than the control conditions. 

CONCLUSIONS: There is a lack of quality of the evidence for FRIENDS, SSL and SASS, due to inconsistencies on the outcome assessments, statistical analyses, and the fidelity measures adopted in individual studies. Insufficient school funding and workforce with relevant health background, and the low level of parental involvement in the intervention would be the major challenges in school-based CBT for children and adolescents with SAD or social anxiety symptoms.
AN  - 36940221
AU  - Tse,
AU  - Z.
AU  - W.
AU  - M.
AU  - Emad,
AU  - S.
AU  - Hasan,
AU  - M.
AU  - K.
AU  - Papathanasiou,
AU  - I.
AU  - V.
AU  - Rehman,
AU  - I.
AU  - U.
AU  - Lee,
AU  - K.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0283329
L1  - internal-pdf://0049140027/Tse-2023-School-based cognitive-behavioural th.pdf
PY  - 2023
SP  - e0283329
T2  - PLoS ONE [Electronic Resource]
TI  - School-based cognitive-behavioural therapy for children and adolescents with social anxiety disorder and social anxiety symptoms: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36940221
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0283329&amp;type=printable
VL  - 18
ER  -
TY  - JOUR
AB  - **Background:** 
SPN-812 has been approved for attention-deficit/hyperactivity disorder (ADHD) treatment in children and adolescents. 

**Objective:** 
We aimed to analyze the efficacy and safety of different doses of SPN-812 for ADHD pediatric patients of different ages, verify its clinical efficacy, and evaluate its safety. 

**Methods:** 
Up until 30 August 2023, randomized controlled trials (RCTs) were searched in EMBASE, MEDLINE, the Cochrane Library, and clinicaltrials.gov to evaluate different doses of SPN-812 and a placebo. 

**Results:** 
We pooled 1619 patients from five RCTs with a duration of 6-8 weeks. Patients (6-17 years old) in SPN-812 (100, 200, and 400 mg/d) groups were superior to the control group in all efficacy outcomes with lower attention-deficit/hyperactivity disorder rating scale-5 (ADHD-RS-5), Conners 3-parent short form composite T score (Conners 3-PS), Weiss functional impairment rating scale-parent (WFIRS-P), and increased clinical global impression-improvement (CGI-I) score (both p &lt; 0.05). At the same time, only SPN-812 300 mg/d did not show a significantly high risk of the adverse events (AEs) such as somnolence and decreased appetite (p = 0.09). There was no significant difference between placebo and SPN-812 groups (100, 200, and 400 mg/d) in serious adverse events (SAEs) such as syncope. The subgroup analyses showed that, both in children and adolescents subgroups, SPN-812 showed better efficacy than the placebo. The two age subgroups showed a significantly higher risk of AEs and an insignificant risk of SAEs than the placebo. 

**Conclusion:** 
At present, SPN-812 (100, 200, and 400 mg/d) is superior to the corresponding control in efficacy measures. However, the safety problem cannot be ignored.
AN  - WOS:001132498100001
AU  - Tan,
AU  - X.
AU  - Xu,
AU  - Y.
AU  - J.
AU  - Wang,
AU  - S.
AU  - X.
AU  - Li,
AU  - J.
AU  - X.
AU  - Hu,
AU  - C.
AU  - X.
AU  - Chen,
AU  - Z.
AU  - Q.
AU  - Cheng,
AU  - Q.
AU  - Z.
AU  - Wang,
AU  - Z.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3390/brainsci13121627
L1  - internal-pdf://3846081887/Tan-2023-Efficacy and Safety of SPN-812 (Exten.pdf
PY  - 2023
SP  - 13
T2  - Brain Sciences
TI  - Efficacy and Safety of SPN-812 (Extended-Release Viloxazine) in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:001132498100001
UR  - https://mdpi-res.com/d_attachment/brainsci/brainsci-13-01627/article_deploy/brainsci-13-01627-v2.pdf?version=1701759273
VL  - 13
ER  -
TY  - JOUR
AB  - BACKGROUND: Children of parents with mental disorders have a relatively high risk of developing a mental illness or behavioural disorder. 

OBJECTIVE: The aim of this systematic review was to evaluate the efficacy of preventive psychotherapeutic interventions in children of parents with mental illness. In particular, the development of mental illness and/or psychological symptomatology in this population was assessed. 

METHOD: This qualitative systematic review looked at interventions targeting children aged 4-18 years without a diagnosed mental disorder, alone or with their families, with a parent with a diagnosed mental disorder. The protocol was pre-registered in Open Science Framework. A total of 1255 references were retrieved from MEDLINE, PsychArticles, PsycINFO, Springer Link, Science Direct, Scopus and WOS databases, and 12 references from grey literature. This search was replicated by an external reviewer. 

RESULTS: Fifteen studies involving 1941 children and 1328 parents were included. Interventions were based on cognitive-behavioural and/or psychoeducational components, including six randomized controlled trials. Internalizing symptomatology was assessed in 80% of the studies, externalizing and prosocial behaviour in 47%, and coping style in 33%. Only two studies measured the future risk of developing a mental disorder (ORs of 2.37 and 6.6). There was variability in the format of the intervention (group; family) as well as in the type of intervention and its duration (from one session to 12 sessions). 

CONCLUSIONS: Interventions for children of parents with mental disorder were clinically and statistically significant, especially in preventing internalizing symptomatology at one-year follow-up, with effect sizes ranging from d = -0.28 to 0.57 (95% CI).
AN  - 36997159
AU  - Puchol-Martinez,
AU  - I.
AU  - Vallina
AU  - Fernandez,
AU  - O.
AU  - Santed-German,
AU  - M.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/cpp.2850
L1  - internal-pdf://3829516479/Puchol-Martinez-2023-Preventive interventions.pdf
PY  - 2023
SP  - 30
T2  - Clinical Psychology &amp; Psychotherapy
TI  - Preventive interventions for children and adolescents of parents with mental illness: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36997159
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpp.2850?download=true
VL  - 30
ER  -
TY  - JOUR
AB  - Global guidelines emphasize the critical role of responsive caregiving in terms of reducing violence against children and promoting early childhood development. However, there is an absence of global evidence synthesis on the effects of early childhood parenting programs for children with developmental disabilities. This systematic review and meta-analysis aims to investigate the effectiveness of parenting interventions delivered for preschool-age children with developmental disabilities in reducing violence against children, altering violence-related factors, and promoting child development. We searched for randomized controlled trials with inactive control. Estimates were pooled using robust variance estimations. Meta-regressions were conducted to explore sources of heterogeneity. In all, 33 studies met the inclusion criteria. The results showed that parenting programs improved child behavior, parental mental health, parenting practices, parental self-efficacy, parent-child interaction, child language skills, and child social skills post-intervention. No studies provided data on the actual occurrence of violence against children. Effects might vary by diagnosis, delivery modality, and world region. The findings supported the delivery of parenting programs to alter factors associated with violence against children and promote child language and social skills for families of young children with developmental disabilities, especially attention deficit hyperactivity disorder, autism, intellectual disability, and language disorders. More research using rigorous methods, long-term follow-ups, and transparent reporting is needed, particularly within more low- and middle-income countries.
AN  - 37978829
AU  - Fang,
AU  - Z.
AU  - Liu,
AU  - X.
AU  - Zhang,
AU  - C.
AU  - Lachman,
AU  - J.
AU  - M.
AU  - Qiao,
AU  - D.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/15248380231207965
L1  - internal-pdf://2957121273/fang-et-al-2023-parenting-interventions-that-p.pdf
PY  - 2023
SP  - 15248380231207965
T2  - Trauma Violence &amp; Abuse
TI  - Parenting Interventions That Promote Child Protection and Development for Preschool-Age Children with Developmental Disabilities: A Global Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37978829
ER  -
TY  - JOUR
AB  - **Background:** 
People forced to leave their homes, such as refugees and internally displaced persons, are exposed to various stressors during their forced displacement, putting them at risk for mental disorders. 

**Objective:**
To summarize evidence on the efficacy of psychosocial interventions aiming to promote mental health and/or to prevent mental symptoms by fostering transdiagnostic skills in forcibly displaced persons of all ages. 

**Method:** 
Four databases and reference lists were searched for randomized controlled trials on interventions in this population on 11 March 2022. Thirty-six studies were eligible, 32 studies (comprising 5299 participants) were included in random-effects multilevel meta-analyses examining the effects of interventions on mental symptoms and positive mental health (e.g. wellbeing) as well as moderators to account for heterogeneity. OSF Preregistration-ID: 10.17605/OSF.IO/XPMU3

**Results:** 
Our search resulted in 32 eligible studies, with 10 reporting on children/adolescents and 27 on adult populations. There was no evidence for favourable intervention effects in children/adolescents, with 44.4% of the effect sizes pointing to potentially negative effects yet remaining non-significant. For adult populations, our meta-analyses showed a close-to-significant favourable effect for mental symptoms, M(SMD) = 0.33, 95% CI [-0.03, 0.69], which was significant when analyses were limited to high-quality studies and larger for clinical compared to non-clinical populations. No effects emerged for positive mental health. Heterogeneity was considerable and could not be explained by various moderators (e.g. type of control, duration, setting, theoretical basis). Certainty of evidence was very low across all outcomes limiting the generalizability of our findings. 

**Conclusion:** 
The present review provides at most weak evidence for an effect favouring transdiagnostic psychosocial interventions over control conditions for adult populations but not for children and adolescents. Future research should combine the imperative of humanitarian aid in face of major crises with studying the diverse needs of forcibly displaced persons to improve and tailor future interventions.
AN  - 37305944
AU  - Schafer,
AU  - S.
AU  - K.
AU  - Kunzler,
AU  - A.
AU  - M.
AU  - Lindner,
AU  - S.
AU  - Broll,
AU  - J.
AU  - Stoll,
AU  - M.
AU  - Stoffers-Winterling,
AU  - J.
AU  - Lieb,
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/20008066.2023.2196762
L1  - internal-pdf://2481120256/Schafer-2023-Transdiagnostic psychosocial inte.pdf
PY  - 2023
SP  - 2196762
T2  - European Journal of Psychotraumatology
TI  - Transdiagnostic psychosocial interventions to promote mental health in forcibly displaced persons: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=37305944
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262817/pdf/ZEPT_14_2196762.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - This review examines the effectiveness of positive parenting interventions aimed at improving sensitivity, responsiveness, and/or non-harsh discipline on children&#039;s early cognitive skills, in four meta-analyses addressing general mental abilities, language, executive functioning, and pre-academics. The objectives are to assess the magnitude of intervention effectiveness and identify moderators of effectiveness. We include randomized controlled trials of interventions targeting positive parenting to improve cognition in children &lt; 6 years. Studies that include children with neurodevelopmental and/or hearing disorders were excluded. MEDLINE, PsycINFO, ERIC, and ProQuest Dissertations &amp; Theses (October 2021) and citation chaining identified relevant records. Five reviewers completed screening/assessments, extraction, and risk of bias. Pooled analysis in Comprehensive Meta-Analysis (Version 3) used random effects modeling, with moderation via Q-statistics and meta-regression. Positive parenting interventions led to significant improvements in mental abilities (g = 0.46, N = 5746; k = 33) and language (g = 0.25, N = 6428; k = 30). Effect sizes were smaller and nonsignificant for executive functioning (g = 0.07, N = 3628; k = 14) and pre-academics (g = 0.16, N = 2365; k = 7). Robust moderators emerged for language and cognition. For cognition, studies with higher risk of bias scores yielded larger intervention effects. For language, studies with younger children had larger effect sizes. Studies mitigated selection and detection bias, though greater transparency of reporting is needed. Interventions that promote parental sensitivity, responsiveness, and non-harsh discipline improve early mental abilities and language. Studies examining executive functioning and pre-academics are needed to examine moderators of intervention effectiveness. Trial registration Systematic review PROSPERO registration. CRD42020222143.
AN  - 36729307
AU  - Prime,
AU  - H.
AU  - Andrews,
AU  - K.
AU  - Markwell,
AU  - A.
AU  - Gonzalez,
AU  - A.
AU  - Janus,
AU  - M.
AU  - Tricco,
AU  - A.
AU  - C.
AU  - Bennett,
AU  - T.
AU  - Atkinson,
AU  - L.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s10567-022-00423-2
L1  - internal-pdf://0719129335/Prime-2023-Positive Parenting and Early Childh.pdf
PY  - 2023
SP  - 02
T2  - Clinical Child &amp; Family Psychology Review
TI  - Positive Parenting and Early Childhood Cognition: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36729307
UR  - https://link.springer.com/content/pdf/10.1007/s10567-022-00423-2.pdf
VL  - 02
ER  -
TY  - JOUR
AB  - Background and
AN  - 36837594
AU  - Ang,
AU  - L.
AU  - Kim,
AU  - J.
AU  - T.
AU  - Kim,
AU  - K.
AU  - Lee,
AU  - H.
AU  - W.
AU  - Choi,
AU  - J.
AU  - Y.
AU  - Kim,
AU  - E.
AU  - Lee,
AU  - M.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/medicina59020392
L1  - internal-pdf://2337038530/Ang-2023-Acupuncture for Treating Attention De.pdf
PY  - 2023
SP  - 17
T2  - Medicina
TI  - Acupuncture for Treating Attention Deficit Hyperactivity Disorder in Children: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36837594
UR  - https://mdpi-res.com/d_attachment/medicina/medicina-59-00392/article_deploy/medicina-59-00392.pdf?version=1676621557
VL  - 59
ER  -
TY  - JOUR
AB  - Anxiety problems are common in children and can have profound adverse effects on personal, social and academic life. Almost 40% of anxiety disorders emerge before age 14, making primary schools invaluable settings for prevention and early support of child anxiety. Research indicates that school-based interventions can be costly and difficult to schedule, school staff lack confidence to deliver them effectively, and outcomes are mixed. One solution may be for school staff to adapt and enhance their day-to-day practices to better support children with anxiety. 

This systematic review aims to summarise what is known about the relationship between teachers&#039; classroom management and anxiety in primary school-aged children. We searched ASSIA, British Education Index, Education Abstracts, Embase, ERIC, MEDLINE, PsycINFO and Scopus in December 2020 and June 2022, using a predefined strategy. We included studies of any design, published in peer-reviewed journals at any time, in any language, reporting associations between day-to-day classroom management strategies/methods and anxiety/internalising outcomes in children aged 4-11 years, taught in mainstream primary schools. Studies were assessed for quality/risk of bias. 

We identified eight studies (six quantitative, two qualitative) including 4505 children. We found some evidence that authoritarian, controlling and punitive classrooms may be linked to higher levels of anxiety, although, overall, existing evidence indicates either a weak or no association between classroom management and anxiety. This review highlights a paucity of research in this area. Furthermore, variability in design, measures and quality makes drawing firm conclusions difficult. Recommendations for future research are discussed. Rationale for this studyContext and Implications This review explores what is currently known about the relationship between teachers&#039; day-to-day classroom management practices and anxiety in primary school-aged children. Implications for researchers and practitionersWhy the findings matterAnxiety problems are common and often start in the primary years, however there is scant evidence to inform primary school educators on how day-to-day classroom practices can be used to better support children with or at risk of anxiety problems. This review is relevant for primary classroom practitioners, school leaders, education professionals, academics, researchers and policymakers keen to better understand how to support those with or at risk of anxiety. Although overall findings indicate very small associations between teaching styles/practices and anxiety in children, there is very little research to draw on. Research is urgently needed that uses robust designs to focus on whether specific, feasible, day-to-day strategies can be used by school staff to effectively manage and minimise children&#039;s anxiety problems and, if so, how school staff can best be supported and equipped to deliver them.
AN  - WOS:000922491300001
AU  - Manley,
AU  - H.
AU  - Tu,
AU  - E.
AU  - N.
AU  - Reardon,
AU  - T.
AU  - Creswell,
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1002/rev3.3385
L1  - internal-pdf://1356662700/Manley-2023-The relationship between teachers&#039;.pdf
PY  - 2023
SP  - 22
T2  - Review of Education
TI  - The relationship between teachers&#039; day-to-day classroom management practices and anxiety in primary school children: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000922491300001
UR  - https://bera-journals.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/rev3.3385?download=true
VL  - 11
ER  -
TY  - JOUR
AB  - A systematic review and meta-analysis were utilised to explore the methodological quality, program fidelity, and efficacy of social skills group programs (SSGPs) aiming to support autistic adolescents in navigating their everyday social worlds. The study evaluated the methodological quality and theoretical fidelity of studies, with a random effect meta-analysis conducted to summarise the overall efficacy of SSGP and its effect on social communication and interaction, behavioural/emotional challenges, adaptive functioning, and autism characteristics. Although findings from the 18 identified studies indicated an adjusted medium overall effect with these programs successfully supporting autistic adolescents&#039; socialisation needs (g = 0. 60, p &lt; 0.001), most studies demonstrated medium to low program fidelity despite their good methodological quality. Given the significant heterogeneity of SSGPs and variations in the design and measurement frameworks of efficacy studies, understanding the generalisability of the findings of this research is unclear.
AN  - 36681732
AU  - Afsharnejad,
AU  - B.
AU  - Black,
AU  - M.
AU  - H.
AU  - Falkmer,
AU  - M.
AU  - Bolte,
AU  - S.
AU  - Girdler,
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s10803-023-05893-z
L1  - internal-pdf://1263469279/Afsharnejad-2023-The Methodological Quality an.pdf
PY  - 2023
SP  - 21
T2  - Journal of Autism &amp; Developmental Disorders
TI  - The Methodological Quality and Intervention Fidelity of Randomised Controlled Trials Evaluating Social Skills Group Programs in Autistic Adolescents: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36681732
UR  - https://link.springer.com/content/pdf/10.1007/s10803-023-05893-z.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - **Purpose**
Over 240 million children worldwide experience inequities due to disablement/disability. Play is important for children&#039;s global development, to enable participation in life, and has been used in therapeutic settings. The purpose of this systematic review is to determine the effectiveness of play used in therapy for children with disabilities, to explore ways that play is used in therapy, and to classify and map outcome measures used in play-based interventions to the International Classification of Functioning.

**Methods**
A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

**Results**
The search yielded 22 articles eligible for inclusion. A meta-analysis found significant heterogeneity for play-based intervention outcomes, precluding estimates of effectiveness. Body function and structure outcomes accounted for 61% of reported outcome measures.

**Conclusion**
There is a trend towards a small positive effect of play used in therapy for children with disabilities, but certainty of the effect is poor, and replication difficult due to heterogeneous reports of how play is used. Research aims and outcome measures focusing on meaningful aspects of activity and participation in addition to body function and structure domains of the International Classification of Functioning should be considered for play-based interventions for children with disabilities. Play-based interventions trend towards a positive effect on ICF outcomes, but the certainty of effect is limited.Play is used in diverse ways making it a versatile method to promote engagement or deliver therapy to a wide variety of children with disabilities.Play-based studies measuring outcomes solely related to body function and structure domains of the ICF may not capture the broader holistic benefits of play.When using play in clinical practice, professionals should consider the child&#039;s personal and environmental factors and the influence of play on activity and participation.
AN  - WOS:001075665100001
AU  - Carrington,
AU  - L.
AU  - Hale,
AU  - L.
AU  - Freeman,
AU  - C.
AU  - Smith,
AU  - D.
AU  - Perry,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1080/09638288.2023.2259305
L1  - internal-pdf://3241152812/The effectiveness of play as an intervention u.pdf
PY  - 2023
SP  - 22
T2  - Disability and Rehabilitation
TI  - The effectiveness of play as an intervention using International Classification of Functioning outcome measures for children with disabilities - a systematic review and meta-synthesis
UR  - &lt;Go to ISI&gt;://WOS:001075665100001
ER  -
TY  - JOUR
AB  - **Objectives:** 
The purpose of the current study was to consider the omnibus magnitude and direction of treatment effects associated with parent-inclusive interventions (PII) when compared to no treatment and nonparent-inclusive interventions (NPII) alternatives as well as sample and study characteristics associated with observed treatment effects. 

**Method:** 
We compared the treatment effects of child counseling interventions involving parents to NPII using meta-analysis of 59 randomized controlled studies found through four academic databases. Studies were included if they were published in English and between 1995 and 2019 in peer-reviewed and academic capstone projects, implemented randomized controlled trial methodology, participants were children ages 3&ndash;11, data were associated with primary studies, and they included some aspect of parental intervention. Analysis included synthesis of Hedge&rsquo;s g effect size, heterogeneity analysis, and moderator analysis. 

**Results:** 
The 59 studies included in the analysis yielded 5,317 participants with a mean age of 7.57. Participants predominantly identified as White (74%), female (58%), and 59% of the sample were eligible for free or reduced school lunch. Results suggested that those who received parent-inclusive treatment reported fewer symptoms as compared to thosewho received no treatment with a medium effect size (&minus;0.540, 95% confidence interval, CI [&minus;0.679, &minus;0.400], &tau;2 = 0.081, p , .001). The 60 effect sizes included in the analysis of associations between parent-inclusive and nonparent-inclusive treatment outcomes (N= 45) yielded a mean effect size of&minus;0.322, 95% CI [&minus;0.456, &minus;0.189], &tau;2 = 0.166, p , .001, indicative of a small effect size and suggesting participants who received PII tended to report fewer symptoms at the end of treatment when compared to those who received NPII. Furthermore, presenting concern, treatment modality, and race and ethnicity of participants statistically significantly moderated the mean effect size. Specifically, studies that involved diverse clients outperformed studies with more homogenous samples, and treatments targeting symptoms of anxiety and autism spectrum disorder yielded higher effect sizes than other presenting concerns. Interventions taking place in schools or inpatient settings outperformed other settings, and individual and family modalities outperformed group and multimodal approaches. Age, gender, and type of parent involvement did not yield statistically significant differences. 

**Discussion:** 
This study suggests that therapy treatments that involve parents are more effective in treating child mental health symptoms than treatments that do not involve parents. Implications are especially noteworthy for mental health therapists working with children with anxiety or autism spectrum disorder, diverse client populations, and those working in schools and inpatient settings. The demographics of participants in this study limit generalizability to older children and adolescents as well as more diverse populations. Future studies would benefit from considering additional moderating variables as the current study was limited due to narrow measures in outcome research.
AD  - StephenLine, Ahou Vaziri: ahou.line@unt.eduLine, Ahou Vaziri: Department of Counseling, University of North Texas, 1155 Union Circle, #310829, Denton, TX, US, 76203, ahou.line@unt.eduLine, Ahou Vaziri: Department of Counseling, University of North Texas, Denton, TX, USLenz, A. Stephen: Department of Counseling, Health and Kinesiology, Texas A&amp;M University-San Antonio, San Antonio, TX, USWarwick, Lindsey: Department of Clinical Mental Health Counseling, Southern Oregon University, OR, USBranch, Marianna L.: School of Counseling, Walden University, MN, USLemberger-Truelove, Matthew E.: Department of Counseling, University of North Texas, Denton, TX, US
AN  - 2024-12991-001
AU  - Line,
AU  - A.
AU  - V.
AU  - Lenz,
AU  - A.
AU  - Warwick,
AU  - L.
AU  - Branch,
AU  - M.
AU  - L.
AU  - Lemberger-Truelove,
AU  - M.
AU  - E.
DA  - Sep
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/cps0000180
DP  - Ovid Technologies
KW  - meta-analysis
KW  - child psychotherapy
KW  - parent involvement
KW  - treatment outcomes
KW  - *Child Psychotherapy
KW  - *Intervention
KW  - *Parental Involvement
KW  - *Parents
KW  - *Treatment Outcomes
KW  - Psychotherapy &amp; Psychotherapeutic Counseling [3310]
KW  - Human
L1  - internal-pdf://2046187432/2024-12991-001.cleaned.pdf
LA  - English
M3  - Meta Analysis
N1  - PS - First Posting
PY  - 2023
SP  - No Pagination Specified
T2  - Clinical Psychology: Science and Practice
TI  - A meta-analysis of parent-inclusive child therapy interventions for decreasing symptomatology
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2024-12991-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2Fcps0000180&amp;issn=0969-5893&amp;isbn=&amp;volume=&amp;issue=&amp;spage=No&amp;pages=No+Pagination+Specified&amp;date=2023&amp;title=Clinical+Psychology%3A+Science+and+Practice&amp;atitle=A+meta-analysis+of+parent-inclusive+child+therapy+interventions+for+decreasing+symptomatology.&amp;aulast=Line&amp;pid=%3Cauthor%3ELine%2C+Ahou+Vaziri%3C%2Fauthor%3E%3CAN%3E2024-12991-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Objective:**

This systematic review and meta-analysis investigates the effects of emotionally oriented parental interventions. 

**Background:**

Several emotionally oriented parental interventions have been developed during the last decade. Some of these have gained popularity and spread across several continents. The literature is growing and consists of qualitative studies; intervention only, quasi-experimental, case-control studies; and randomized controlled trials. They indicate effects for parents and children. However, no systematic review or meta-analysis has, to our knowledge, summarized the results. 

**Method:**

Using several search engines, we located 8,272 studies. After abstract and full-text screening, 33 studies were assessed for bias and included in the study. Outcomes for parents and children were extracted and combined into three constructs for parents and two for children. Meta-analyses were conducted for each construct to estimate the effect of the interventions using a robust Bayes meta-analysis. 

**Results:**

The results indicate the presence of a small to medium effect on parents&#039; mental health, behavior, and use of emotionally oriented parenting, as well as on children&#039;s internalizing and externalizing difficulties. Most participants were recruited from the general population, and clinical settings were rare. The results show little evidence of publication bias. 

**Conclusion:**

There is evidence of a small to medium effect of emotionally oriented interventions on parents and children. Systematic review registration: https://osf.io/un3q4/.
AN  - 37519350
AU  - Zahl-Olsen,
AU  - R.
AU  - Severinsen,
AU  - L.
AU  - Stiegler,
AU  - J.
AU  - R.
AU  - Fernee,
AU  - C.
AU  - R.
AU  - Simhan,
AU  - I.
AU  - Rekdal,
AU  - S.
AU  - S.
AU  - Bertelsen,
AU  - T.
AU  - B.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyg.2023.1159892
L1  - internal-pdf://3124638598/Zahl-Olsen-2023-Effects of emotionally oriente.pdf
PY  - 2023
SP  - 1159892
T2  - Frontiers in Psychology
TI  - Effects of emotionally oriented parental interventions: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37519350
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374204/pdf/fpsyg-14-1159892.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - The psychosocial health of children and adolescents has been particularly affected by the COVID-19 pandemic. Containment measures have restricted social development, education and recreational activities, may have increased family conflicts and, in many cases, led to feelings of loneliness, sleep disturbances, symptoms of anxiety and depression. We conducted a systematic review to identify interventions that seek to ameliorate these detrimental effects of the COVID-19 pandemic and to build resilience in children and adolescents. Literature searches were conducted in the databases MEDLINE, EMBASE, PsycINFO, CENTRAL, WHO COVID-19 Global literature on coronavirus disease and Cochrane COVID-19 Study Register (up to 30 June 2022). The searches retrieved 9557 records of which we included 13 randomized-controlled trials (RCTs) for evidence synthesis. Included studies predominantly implemented online group sessions for school-aged children with either a psychological component, a physical activity component, or a combination of both. A meta-analysis of seven studies on anxiety and five on depressive symptoms provided evidence for a positive effect of interventions by reducing anxiety (Standardized Mean Difference (SMD) (95% CI): - 0.33 (- 0.59; - 0.06)) and depressive symptoms (SMD (95% CI): - 0.26 (- 0.36; - 0.16)) compared to the control interventions. Studies also showed improvements in positive mental health outcomes, such as resilience (n = 2) and mental and psychological wellbeing (n = 2). Exploratory subgroup analyses suggested a greater effectiveness of interventions that (i) are of higher frequency and duration, (ii) enable personal interaction (face-to-face or virtually), and (iii) include a physical activity component. Almost all studies were judged to be at high risk of bias and showed considerable heterogeneity. Further research may focus on the contribution of different intervention components or distinct subgroups and settings, and should examine children and adolescents over longer follow-up periods.
AN  - 37573565
AU  - Wendel,
AU  - F.
AU  - Bender,
AU  - S.
AU  - Breitinger,
AU  - E.
AU  - Coenen,
AU  - M.
AU  - Hummel,
AU  - J.
AU  - Immich,
AU  - G.
AU  - Kirschneck,
AU  - M.
AU  - Klunder,
AU  - V.
AU  - Kunzler,
AU  - A.
AU  - M.
AU  - Lieb,
AU  - K.
AU  - Movsisyan,
AU  - A.
AU  - Li,
AU  - L.
AU  - Y.
AU  - Ravens-Sieberer,
AU  - U.
AU  - Rehfuess,
AU  - E.
AU  - Voss,
AU  - S.
AU  - Jung-Sievers,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-023-02280-y
L1  - internal-pdf://1235858240/Wendel-2023-Interventions to build resilience.pdf
PY  - 2023
SP  - 13
T2  - European Child &amp; Adolescent Psychiatry
TI  - Interventions to build resilience and to ameliorate negative psychosocial effects of the COVID-19 pandemic on children and adolescents: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=37573565
UR  - https://link.springer.com/content/pdf/10.1007/s00787-023-02280-y.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Psychoeducation is a common element in psychological interventions for youth depression and anxiety, but evidence about its use with youth perinatally is limited. AIMS: This review aims to understand outcomes and mechanisms of psychoeducation for the indicated prevention and treatment of perinatal depression and anxiety in youth. 

METHOD: 
For this review, we synthesised published quantitative and qualitative evidence. Seven databases (ASSIA, Medline, PubMed, PsycINFO, PsycArticles, Scopus and Web of Science) were searched for studies published before 10 August 2021. We also had consultations with a youth advisory group (N = 12). 

RESULTS: 
In total, 20 studies met the inclusion criteria. Seven quantitative studies examined multicomponent interventions that included psychoeducation, and one study evaluated psychoeducation as a standalone intervention for postnatal depression. Multicomponent interventions showed significant effects on postnatal depression in two out of six studies, as well as being effective at reducing prenatal anxiety in one study. Standalone psychoeducation for postnatal depression was also effective in one study. Evidence from 12 qualitative studies, corroborated by commentaries from the youth advisory group, suggested that psychoeducation could increase knowledge about symptoms, generate awareness of relevant services and enhance coping. 

CONCLUSIONS: 
Psychoeducation may be an important foundational ingredient of interventions for perinatal depression and, potentially, anxiety in adolescents and young adults through stimulating help-seeking and self-care.
AN  - 38088162
AU  - Mhango,
AU  - W.
AU  - Crowter,
AU  - L.
AU  - Michelson,
AU  - D.
AU  - Gaysina,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/bjo.2023.614
L1  - internal-pdf://1015429513/Mhango-2023-Psychoeducation as an active ingre.pdf
PY  - 2023
SP  - e10
T2  - BJPsych Open
TI  - Psychoeducation as an active ingredient for interventions for perinatal depression and anxiety in youth: a mixed-method systematic literature review and lived experience synthesis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=38088162
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10755556/pdf/S2056472423006142a.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - Mental health problems are a leading cause of health-related disability among children and adolescents. Organized activities are a possible preventive factor for mental health problems. An aggregated overview of evidence is relevant for youth policymakers and is lacking so far. Thus we aim to provide an overview of published systematic reviews and meta-analyses on the impact of participation in organized sport and non-sport activities (e.g. arts, music) on childhood and adolescent mental health. 

Systematic reviews were identified through a search in five databases (Embase, MEDLINE, Web of Science core collection, CINAHL and PsycINFO) on 25-March-2021. Systematic reviews about organized activities and mental health outcomes in 0-21-year-olds published in English were included. Two independent reviewers assessed titles, abstracts and full texts, performed data-extraction and quality assessment using the AMSTAR-2 and assessed the quality of evidence. 

Out of 833 studies, six were considered eligible. Quality of the reviews ranged from critically low to moderate. Most reviews focused on organized sport activities, focusing on: team sport, level of sport involvement, extracurricular and community sport activities. Indications of a positive impact on mental health outcomes were found for participation in team sport, in (school) clubs, and in extracurricular and community sport and non-sport activities. 

We found a small positive impact of organized sport activities on mental health outcomes among children and adolescents. This seems not to depend on any specific type of organized sport activity. Limited evidence was found for organized non-sport activities. Copyright &copy; 2022 The Authors
AN  - 2016195458
AU  - Boelens,
AU  - M.
AU  - Smit,
AU  - M.
AU  - S.
AU  - Raat,
AU  - H.
AU  - Bramer,
AU  - W.
AU  - M.
AU  - Jansen,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.pmedr.2021.101687
L1  - internal-pdf://1421971664/Impact of organized activities on mental-2022.pdf
internal-pdf://1215598879/Impact of organized activities on mental-20221.pdf
PY  - 2022
T2  - Preventive Medicine Reports
TI  - Impact of organized activities on mental health in children and adolescents: An umbrella review
UR  - https://www.journals.elsevier.com/preventive-medicine-reports
VL  - 25 (no pagination)
ER  -
TY  - JOUR
AB  - Play is an indispensable part of growing up and by using play to distract children while undergoing invasive procedures can have a positive impact. Play can help children to cope with painful procedures and long-term treatment.

The aim of the review was to evaluate the evidence concerning the effect of play on anxiety among children undergoing invasive procedures. 

This is a systematic review and meta-analysis. Data sources: PubMed, The MEDLINE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Clinical Key, Cochrane Library, and Google Scholar were searched between 2012 and 2020. 

Review methods: randomized controlled trials (RCTs) that evaluated the effectiveness of play on anxiety among children undergoing invasive procedures were included. Meta-analysis was done using Revman v5.3 software. A total of 451 participants from 5 trials were involved in the systemic review and meta-analysis. Self-reported anxiety, parents reported anxiety, and self-reported pain were found significant in intervention [chi2 = 7.57, df = 2 at P &lt; 0.02]. When compared with control group, the review result revealed that experimental group reduced the anxiety and pain (P &lt; 0.05). Copyright &copy; 2022, The Author(s), under exclusive licence to Indian Association of Surgical Oncology.
AN  - 2018197201
AU  - Halemani,
AU  - K.
AU  - Issac,
AU  - A.
AU  - Mishra,
AU  - P.
AU  - Dhiraaj,
AU  - S.
AU  - Mandelia,
AU  - A.
AU  - Mathias,
AU  - E.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s13193-022-01571-1
L1  - internal-pdf://4095394663/Halemani-2022-Effectiveness of Preoperative Th.pdf
PY  - 2022
T2  - Indian Journal of Surgical Oncology.
TI  - Effectiveness of Preoperative Therapeutic Play on Anxiety Among Children Undergoing Invasive Procedure: a Systematic Review and Meta-analysis
UR  - http://www.springer.com/medicine/oncology/journal/13193
UR  - https://link.springer.com/article/10.1007/s13193-022-01571-1
UR  - https://link.springer.com/content/pdf/10.1007/s13193-022-01571-1.pdf
ER  -
TY  - JOUR
AB  - OBJECTIVE: To systematically review and meta-analyze the effectiveness of family therapy compared to other active treatments for adolescents with depressive disorders or suicidal ideation. 

METHOD: We conducted a systematic search of The Cochrane Central Register of Controlled Trials, Medline, Embase, PsycINFO, AMED, CINAHL and Web of Science and performed two meta-analyses of outcomes for depressive symptoms and suicidal ideation. 

RESULTS: We screened 5,940 records and identified 10 randomized controlled studies of family therapy for depressive disorder or suicidal ideation in adolescents with an active treatment comparison group. Nine studies reported outcome measures of depressive symptoms and four reported outcome measures of suicidal ideation. The meta-analysis showed no significant difference between family therapy and active comparison treatments for end-of-treatment levels of depression. For suicidal ideation our meta-analysis showed a significant effect in favour of family therapy over comparison treatments for suicidal ideation. 

CONCLUSIONS: Based on the current body of research, we found that family therapy is not superior to other psychotherapies in the treatment of depressive disorder. However, family therapy leads to significantly improved outcomes for suicidal ideation, compared to other psychotherapies. The evidence for the treatment of depression is of low quality needs more research.
AN  - 36053279
AU  - Waraan,
AU  - L.
AU  - Siqveland,
AU  - J.
AU  - Hanssen-Bauer,
AU  - K.
AU  - Czjakowski,
AU  - N.
AU  - O.
AU  - Axelsdottir,
AU  - B.
AU  - Mehlum,
AU  - L.
AU  - Aalberg,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/13591045221125005
L1  - internal-pdf://3618371126/13591045221125005.cleaned.pdf
PY  - 2022
SP  - 13591045221125005
T2  - Clinical Child Psychology &amp; Psychiatry
TI  - Family therapy for adolescents with depression and suicidal ideation: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36053279
ER  -
TY  - JOUR
AB  - PURPOSE: This systematic review aimed to investigate the effectiveness of home visiting programs targeting parents who have maltreated their children on the prevention of child maltreatment recurrence. 

METHODS: Major databases were searched (Ovid-Medline, PubMed, Cochrane Library, CINAHL, and RISS). The frequency of maltreatment was measured for the meta-analysis, which was conducted using Review Manager 5.2 software. The effect size was measured using odds ratios (ORs). 

RESULTS: Six studies were included in the analysis, none of which were conducted in South Korea. The meta-analysis demonstrated that the risk of child maltreatment recurrence significantly decreased after a home visiting program was implemented (OR=0.45, 95% confidence interval [CI]=0.29-0.68). Nurses were the most common intervention providers. 

CONCLUSION: Home visiting programs should be provided for families in which maltreatment has already occurred to prevent the recurrence of maltreatment and foster a home environment in which children can live safely. Since the rate of child maltreatment in Korea is increasing, further research is needed to develop and implement home visiting programs in which nurses play a major role in preventing the recurrence of child maltreatment.
AN  - 35172079
AU  - Han,
AU  - K.
AU  - Oh,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.4094/chnr.2022.28.1.41
L1  - internal-pdf://2622421916/The effectiveness of home visiting progra-2022.pdf
PY  - 2022
SP  - 41-50
T2  - Child Health Nursing Research
TI  - The effectiveness of home visiting programs for the prevention of child maltreatment recurrence at home: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35172079
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858785/pdf/chnr-28-1-41.pdf
VL  - 28
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
Aripiprazole is often prescribed to young people, although there remain unanswered questions about its effects on weight gain. This study undertook a meta-analysis of weight gain occurring in young people with early psychosis who were prescribed aripiprazole. 

**METHOD**
A systematic search was conducted for studies reporting on aripiprazole and weight change in young people with a psychotic disorder. A meta-analysis integrated the data into an estimate of effect size. 

**RESULTS**
Eleven studies met the inclusion criteria amounting to 886 participants (mean age 18 years). The results showed significant weight gain averaging 2.7 kg. These increases were associated with a longer duration of exposure to aripiprazole but not a higher dosage. 

**CONCLUSIONS**
The results highlight the importance of regular patient monitoring and the early implementation of interventions to manage antipsychotic-related weight gain.
AN  - 35001673
AU  - Parmar,
AU  - A.
AU  - Hulme,
AU  - D.
AU  - Hacking,
AU  - D.
AU  - Shymko,
AU  - G.
AU  - Dragovic,
AU  - M.
AU  - Terina,
AU  - G.
AU  - Waters,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/10398562211037334
L1  - internal-pdf://2104927274/Aripiprazole in young people with early p-2022.pdf
PY  - 2022
SP  - 10398562211037334
T2  - Australasian Psychiatry
TI  - Aripiprazole in young people with early psychosis: a systematic review and meta-analysis of weight gain
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35001673
ER  -
TY  - JOUR
AB  - Autism Spectrum Disorder (ASD) is a constellation of social communication problems in addition to unusual and repetitive behaviors. In this review, we aimed to investigate the effects of probiotics, prebiotics or synbiotics on gastrointestinal (GI) and behavioral symptoms of ASD. We searched the relevant literature in several electronic databases. In total, 344 children with ASD were investigated in this review. The results of this review demonstrated significant effects of the intervention with probiotics and prebiotics on all domains of Autism Treatment Evaluation Checklist (ATEC) score. There were also different reports about their beneficial effects on the improvement of gastrointestinal symptoms, although a need for more clinical trials with the same doses and types of microorganisms is also highlighted.
AD  - [Azari, Hushyar] Urmia Univ Med Sci, Fac Med, Orumiyeh, Iran. [Morovati, Ashti] Tabriz Univ Med Sci, Fac Nutr &amp; Food Sci, Tabriz, Iran. [Gargari, Bahram Pourghassem] Tabriz Univ Med Sci, Fac Nutr &amp; Food Sci, Nutr Res Ctr, Dept Biochem &amp; Diet Therapy, Tabriz, Iran. [Sarbakhsh, Parvin] Tabriz Univ Med Sci, Fac Hlth, Dept Epidemiol &amp; Biostat, Tabriz, Iran. Science; Tabriz University of Medical Science; Tabriz University of Medical ScienceGargari, BP (corresponding author), Tabriz Univ Med Sci, Fac Nutr &amp; Food Sci, Nutr Res Ctr, Dept Biochem &amp; Diet Therapy, Tabriz, Iran.hushyarazari@hotmail.com; Ashti.morovati@yahoo.com; pourghassemb@tbzmed.ac.ir; sarbakhshp@tbzmed.ac.ir
AN  - WOS:000878941600001
AU  - Azari,
AU  - H.
AU  - Morovati,
AU  - A.
AU  - Gargari,
AU  - B.
AU  - P.
AU  - Sarbakhsh,
AU  - P.
DB  - Alerts 6_2022.enl
DO  - 10.1007/s40489-022-00348-0
J2  - Rev. J. Autism Dev. Disord.
KW  - Autism
KW  - Gut microbiota
KW  - Prebiotic
KW  - Probiotic
KW  - Synbiotic
KW  - gastrointestinal microbiota
KW  - children
KW  - receptor
KW  - level
KW  - Psychology
L1  - internal-pdf://2541141051/Azari-An Updated Systematic Review and Meta-An.pdf
LA  - English
M3  - Review; Early Access
N1  - ISI Document Delivery No.: 5X9VHTimes Cited: 0Cited Reference Count: 84Azari, Hushyar Morovati, Ashti Gargari, Bahram Pourghassem Sarbakhsh, ParvinPourghassem Gargari, Bahram/D-3556-2017Pourghassem Gargari, Bahram/0000-0001-7667-099XTabriz University of Medical SciencesThe authors want to thank Tabriz University of Medical Sciences for their supports.0Springer heidelbergHeidelberg2195-7185
PY  - 2022
SP  - 15
T2  - Review Journal of Autism and Developmental Disorders
TI  - An Updated Systematic Review and Meta-Analysis on the Effects of Probiotics, Prebiotics and Synbiotics in Autism Spectrum Disorder
UR  - &lt;Go to ISI&gt;://WOS:000878941600001
ER  -
TY  - JOUR
AB  - **Purpose of review**
To review the evidence about video game-based therapeutic intervention for people diagnosed with depressive disorders. 

**Recent findings** 
Psychotherapy has been proved to reduce depressive symptoms and is a key element in the treatment of depressive disorders. However, geographical, economical and stigmatized concerns are barriers to access to psychotherapy. New technologies and videos games can overcome some of these barriers by providing teleconferencing evidence-based therapy as time as they may offer an interactive entertainment. 

**Summary**
Overall, video game-based interventions were useful and effective in reducing symptoms of depressive disorders. Seven of the studies were published in the last 5 years, which reflects the increased research interest in video game-based interventions for depression. Overall, when adherence was reported, rates of acceptability and feasibility were high.
AN  - WOS:000751987000001
AU  - Ruiz,
AU  - M.
AU  - Moreno,
AU  - M.
AU  - Girela-Serrano,
AU  - B.
AU  - Diaz-Olivan,
AU  - I.
AU  - Munoz,
AU  - L.
AU  - J.
AU  - Gonzalez-Garrido,
AU  - C.
AU  - Porras-Segovia,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s11920-022-01314-7
L1  - internal-pdf://3842771787/Winning The Game Against Depression_ A Systema.pdf
PY  - 2022
SP  - 13
T2  - Current Psychiatry Reports
TI  - Winning The Game Against Depression: A Systematic Review of Video Games for the Treatment of Depressive Disorders
UR  - &lt;Go to ISI&gt;://WOS:000751987000001
UR  - https://link.springer.com/content/pdf/10.1007/s11920-022-01314-7.pdf
ER  -
TY  - JOUR
AB  - The breadth of available non-pharmacological interventions for autistic children, with varying evidence for efficacy summarised in multiple systematic reviews, creates challenges for parents, practitioners, and policymakers in navigating the research evidence. In this article, we report the findings of an umbrella review of 58 systematic reviews of nonpharmacological interventions for autistic children (aged 0&ndash;12 years). Positive therapeutic effects were identified for Behavioural interventions, Developmental interventions, Naturalistic Developmental Behavioural Interventions, Technology-based interventions, and Cognitive Behaviour Therapy across several child and family outcomes. Positive effects for certain practices within Sensory-based interventions and &lsquo;other&rsquo; interventions were limited to select child and family outcomes. Both inconsistent and null intervention effects were found for Treatment and Education of Autistic and related Communicationhandicapped Children, and Animal-assisted interventions across outcomes. The possible influence of child (chronological age, core autism characteristics, and related skills) and delivery (agent, mode, format, and amount) characteristics on intervention effects was rarely examined, and inconsistent where reported. Twenty-seven systematic reviews (47%) were rated as &lsquo;high&rsquo; quality. Few systematic reviews examined children&rsquo;s participation and quality of life or adverse effects. The findings highlight the need for individualised evidence-based decision-making when selecting interventions for autistic children.
AN  - 36081343
AU  - Trembath,
AU  - D.
AU  - Varcin,
AU  - K.
AU  - Waddington,
AU  - H.
AU  - Sulek,
AU  - R.
AU  - Bent,
AU  - C.
AU  - Ashburner,
AU  - J.
AU  - Eapen,
AU  - V.
AU  - Goodall,
AU  - E.
AU  - Hudry,
AU  - K.
AU  - Roberts,
AU  - J.
AU  - Silove,
AU  - N.
AU  - Whitehouse,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/13623613221119368
L1  - internal-pdf://3236951153/13623613221119368.cleaned.pdf
PY  - 2022
SP  - 13623613221119368
T2  - Autism
TI  - Non-pharmacological interventions for autistic children: An umbrella review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36081343
ER  -
TY  - JOUR
AB  - The effectiveness of anti-cyberbullying interventions reported in the literature has been mixed even when the pedagogical organization of the programs were taken into account. To gain deeper insight into the relationship between pedagogical design principles of anti-cyberbullying interventions and their program effectiveness, this study comprises a systematic review and analysis of the pedagogical characteristics and meta-analyses of anticyberbullying educational programs for adolescents published up to March 2020. Nineteen independent studies from over 2700 articles resulting from systematic searches of six database services met the study selection criteria. A detailed integrated socio-ecological framework was constructed to reveal, for each program component in the selected intervention studies, whether intrapersonal learning, interpersonal interactions, or community-oriented events were involved, and the stakeholders targeted. This pedagogical analysis identified five subgroups. Meta-analysis results of the 19 selected programs found small effect sizes overall for cyberaggression and cyber-victimization. Further explorations showed that the pedagogical design features statistically significantly moderated the effectiveness of the anti-cyberbullying intervention. The subgroup analysis showed that only programs involving interpersonal interactions and stakeholder agency demonstrated superior program effectiveness. Due to the small number of studies that provided data on long-term programs effectiveness, the meta-analysis findings were inconclusive.
AN  - WOS:000759770900008
AU  - Lan,
AU  - M.
AU  - Law,
AU  - N.
AU  - Pan,
AU  - Q.
AU  - Q.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.chb.2022.107200
L1  - internal-pdf://3550275773/Effectiveness of anti-cyberbullying educa-2022.pdf
PY  - 2022
SP  - 16
T2  - Computers in Human Behavior
TI  - Effectiveness of anti-cyberbullying educational programs: A socio-ecologically grounded systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000759770900008
UR  - https://www.sciencedirect.com/science/article/pii/S074756322200022X?via%3Dihub
VL  - 130
ER  -
TY  - JOUR
AB  - **Background**
An unprecedented number of people around the world are experiencing forced displacement due to natural or man‐made events. More than 50% of refugees worldwide are children or adolescents. In addition to the challenges of settling in a new country, many have witnessed or experienced traumatic events. Therefore, refugee children and adolescents are at risk of developing mental health problems such as post‐traumatic stress disorder, and require appropriate and effective support within communities.

**Objectives**
To assess the effectiveness and acceptability of community‐based interventions (RCTs only) in comparison with controls (no treatment, waiting list, alternative treatment) for preventing and treating mental health problems (major depression, anxiety, post‐traumatic stress disorder, psychological distress) and improving mental health in refugee children and adolescents in high‐income countries.

**Search methods**
Databases searches included the Cochrane Common Mental Disorders Controlled Trials Register (all available years), CENTRAL/CDSR (2021, Issue 2), Ovid MEDLINE, Embase, six other databases, and two trials registries to 21 February 2021. We checked reference lists of included study reports. 

**Selection criteria**
Studies of any design were eligible as long as they included child or adolescent refugees and evaluated a community‐based mental health intervention in a high‐income country. At a second stage, we selected randomised controlled trials.

**Data collection and analysis**
For randomised controlled trials, we extracted data relating to the study and participant characteristics, and outcome data relating to the results of the trial. For studies using other evaluation methods, we extracted data relating to the study and participant characteristics. W derived evidence on the efficacy and availability of interventions from the randomised controlled trials only. Data were synthesised narratively.

**Main results**
We screened 5005 records and sought full‐text manuscripts of 62 relevant records. Three randomised controlled trials were included in this review. Key concerns in the risk of bias assessments included a lack of clarity about the randomisation process, potential for bias is outcome measurement, and risk of bias in the selection of results.

**Primary outcomes**
There was no evidence of an effect of community‐based interventions when compared with a waiting list for symptoms of post‐traumatic stress (mean difference (MD) &minus;1.46, 95% confidence interval (CI) &minus;6.78 to 3.86: 1 study; low‐certainty evidence), symptoms of depression (MD 0.26, 95% CI &minus;2.15 to 2.67: 1 study; low‐certainty evidence), and psychological distress (MD &minus;10.5, 95% CI &minus;47.94 to 26.94; 1 study; very low‐certainty evidence). 

There were no data on adverse events.

**Secondary outcomes**
Three trials reported on short‐term changes in child behaviour, using different measures, and found no evidence of an effect of the intervention versus a waiting list (low to very low certainty).

None of the trials reported on quality of life or well‐being, participation and functioning, or participant satisfaction.

**Authors&#039; conclusions**
There is insufficient evidence to determine the efficacy and acceptability of community‐based mental health interventions for refugee children and adolescents.
AU  - Soltan,
AU  - F.
AU  - Cristofalo.
AU  - D.
AU  - Marshall.
AU  - D.
AU  - Purgato,
AU  - M.
AU  - Taddese,
AU  - H.
AU  - Vanderbloemen,
AU  - L.
AU  - Barbui,
AU  - C.
AU  - Uphoff,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013657.pub2
L1  - internal-pdf://2055475875/Soltan_et_al-2022-Cochrane_Database_of_Systema.pdf
PY  - 2022
T2  - Cochrane Database of Systematic Reviews
TI  - Community‐based interventions for improving mental health in refugee children and adolescents in high‐income countries
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** 
A growing literature supports mindfulness and acceptance-based interventions (MABIs) for depression prevention and treatment with individuals from dominant cultural groups, and MABIs have been theorized to be well suited to resonate with individuals from nondominant groups. The aim of the current meta-analysis was to determine whether this promise is realized in practice by evaluating the efficacy of MABIs for depression symptoms in Black Americans. 

**METHOD:** 
Thirty studies with an adequate proportion (&gt;20%) of Black Americans were identified using previous reviews and electronic databases, yielding a total of 1,703 participants with an average proportion of 70% Black Americans. Data on moderators (i.e., geographic location, study design, and intervention protocol) and outcomes were extracted and analyzed using metaregression. 

**RESULTS:** 
Results indicated a moderate effect of MABIs on symptom outcomes in the full sample g = 0.48. Effect sizes were similar in study subsets comprising majority (&gt;50%; k = 19) g = 0.39, and predominantly (&gt;90%; k = 10) g = 0.35, Black participants, with no significant moderating effect of racial composition. Effects were moderated by both sample and intervention level characteristics. 

**CONCLUSIONS:** 
The current findings support the conclusion that MABIs are efficacious to varying degrees for Black Americans; with stronger support for use in adult samples than youth samples. These results are promising, and further support efforts to expand research on evidence-based treatments (EBTs) to meet the specific mental health needs of Black Americans. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
AN  - 35343724
AU  - Dawson,
AU  - D.
AU  - N.
AU  - Jones,
AU  - M.
AU  - C.
AU  - Fairbairn,
AU  - C.
AU  - E.
AU  - Laurent,
AU  - H.
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/ccp0000706
L1  - internal-pdf://3273112518/Mindfulness and acceptance-based interven-2022.pdf
PY  - 2022
SP  - 123-136
T2  - Journal of Consulting &amp; Clinical Psychology
TI  - Mindfulness and acceptance-based interventions with Black Americans: A meta-analysis of intervention efficacy for depressive symptoms
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=35343724
VL  - 90
ER  -
TY  - JOUR
AB  - Public Health Significance Statement The present study indicates that the most common treatment approach for compulsive exercise in people with eating disorders is a multi-component intervention including a combination of psychoeducation and/or psychotherapy and/or structured exercise. Randomized controlled trials (RCTs) suggest that existing multi-component treatments lead to small reductions in compulsive exercise compared with control groups. To date, no research has been conducted on the treatment of compulsive exercise in people with muscle dysmorphia and this represents an important area for future research. A lack of consensus exists among the scientific and medical communities on how to treat compulsive exercise, a core feature of eating disorders (EDs) and muscle dysmorphia (MD). We systematically searched five electronic databases for treatment studies of compulsive exercise that sampled adolescents and/or adults with an ED or MD, assessed longitudinal changes in compulsive exercise and used a validated instrument to measure compulsive exercise or related constructs. We identified 777 papers, of which 18 met eligibility criteria. None of the included studies sampled people with MD and 15 of 18 evaluated multi-component interventions combining psychoeducation and/or psychotherapy and/or structured exercise. Results from meta-analyses indicated moderate-to-large prepost treatment changes in compulsive exercise (Cohen&#039;s d = -.62), but small treatment effects between active and control treatments in randomized controlled trials (Cohen&#039;s d = -.23). Multi-component interventions appear best suited to reduce compulsive exercise in people with EDs, but the optimal combination of treatment components is unknown. Further treatment research on MD is needed.
AN  - WOS:000749773600001
AU  - Martenstyn,
AU  - J.
AU  - A.
AU  - Aouad,
AU  - P.
AU  - Touyz,
AU  - S.
AU  - Maguire,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/cps0000064
L1  - internal-pdf://2608594960/Treatment of Compulsive Exercise in Eating Dis.pdf
PY  - 2022
SP  - 20
T2  - Clinical Psychology-Science and Practice
TI  - Treatment of Compulsive Exercise in Eating Disorders and Muscle Dysmorphia: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000749773600001
ER  -
TY  - JOUR
AB  - OBJECTIVES: Although a number of early childhood development (ECD) interventions in healthcare settings in low- and middle-income countries (LMICs) have been developed to improve parent-directed outcomes and support ECD, their impact have yet to be established. This review assesses the effectiveness of healthcare-based ECD interventions in LMICs on the following key evidence-informed parenting outcomes affecting ECD: (1) responsive caregiving (2) cognitive stimulation and (3) parental mental health. Impacts on parental knowledge regarding ECD and parenting stress were also assessed. 

METHODS: PubMed, PsycINFO, Scopus, CINAHL and Embase were searched. We included randomized controlled trials reporting effects of healthcare-based ECD interventions in LMICs on parent-directed outcomes in the first five years of life. Data extraction included study characteristics, design, sample size, participant characteristics, settings, intervention descriptions, and outcomes. Meta-analyses were conducted using random effects models. 

RESULTS: 8 articles were included. Summary standardized mean differences demonstrated significant benefits of healthcare-based interventions in LMICs for improving: (1) cognitive stimulation (n = 4; SMD = 0.32; 95% CI: 0.08 to 0.56) and (2) ECD knowledge (n = 4; SMD = 0.44; 95% CI: 0.27 to 0.60). No significant effects were seen on maternal depression and parenting stress; only one study assessed parent-child interactions in the context of responsiveness. Limitations included small number of studies for moderation analysis, high heterogeneity, variability in measures used for outcomes and timing of assessments. 

CONCLUSIONS FOR PRACTICE: Our results demonstrate statistically significant effects of healthcare-based interventions in LMICs on improving key evidence-based parenting outcomes and offers one promising strategy to support children reach their full developmental potential.
AN  - 35579803
AU  - Shah,
AU  - R.
AU  - Camarena,
AU  - A.
AU  - Park,
AU  - C.
AU  - Martin,
AU  - A.
AU  - Clark,
AU  - M.
AU  - Atkins,
AU  - M.
AU  - Schwartz,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10995-022-03445-y
L1  - internal-pdf://4266865817/Healthcare-Based Interventions to Improve-2022.pdf
PY  - 2022
SP  - 1217-1230
T2  - Maternal &amp; Child Health Journal
TI  - Healthcare-Based Interventions to Improve Parenting Outcomes in LMICs: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35579803
UR  - https://link.springer.com/article/10.1007/s10995-022-03445-y
UR  - https://link.springer.com/content/pdf/10.1007/s10995-022-03445-y.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - **Background:** 
At present, tic disorder has attracted the attention of medical researchers in many countries. More clinicians choose non-drug therapy, especially cognitive-behavioral therapy (CBT) because of the cognitive side effects of drug therapy. However, few studies had assessed its efficacy. It is necessary to have a more comprehensive understanding of the literature quality of CBT and its intervention effect.

**Methods:** 
In this study, MEDLINE, Embase, and Cochrane were searched from the beginning to June 15, 2021 to study the efficacy of -CBT on tic disorder. Only studies using the Yale Global Tic Severity Scale (YGTSS) and the control group were included.

**Results:**
A total of 12 randomized controlled trials (RCTs), including 536 patients with tic disorders, were identified. The results showed that the effect of CBT was better than that of the control group. The pooled standardized mean difference (SMD) was -0.34 (95% CI: -0.61, -0.07). The effect size of CBT differs from different intervention conditions. In seven studies, the subjects&#039; motor tic scores were counted. The sample size of the experimental group was 224 and that of the control group was 218. The pooled SMD was -0.43 (95% CI: -0.75, -0.11). Seven studies counted the vocal tic scores of subjects, 224 in the experimental group and 218 in the control group. The pooled SMD was -0.22 (95% CI: -0.54, -0.11). Seven studies counted the tic impairment scores of subjects, 220 in the experimental group and 214 in the control group. The pooled SMD was -0.48 (95% CI: -0.73, -0.23).

**Conclusion:** 
The literature shows that different CBTs can significantly reduce the total score of tic disorder and the score of motor tic, but cannot significantly reduce the score of vocal tic. In the future, more new interventions were needed to improve the symptoms of different patients, especially vocal tic.
AN  - WOS:000789611400001
AU  - Shou,
AU  - S.
AU  - T.
AU  - Li,
AU  - Y.
AU  - L.
AU  - Fan,
AU  - G.
AU  - H.
AU  - Zhang,
AU  - Q.
AU  - Yan,
AU  - Y.
AU  - R.
AU  - Lv,
AU  - T.
AU  - Y.
AU  - Wang,
AU  - J.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3389/fpsyg.2022.851250
L1  - internal-pdf://0538719869/The Efficacy of Cognitive Behavioral Ther-2022.pdf
PY  - 2022
SP  - 10
T2  - Frontiers in Psychology
TI  - The Efficacy of Cognitive Behavioral Therapy for Tic Disorder: A Meta-Analysis and a Literature Review
UR  - &lt;Go to ISI&gt;://WOS:000789611400001
VL  - 13
ER  -
TY  - JOUR
AB  - **Background:** 
Autism spectrum disorder (ASD) is a neurodevelopment disorder, marked by deficits in social communication and social interaction as well as by a restricted, repetitive patterns of behaviors, interests and activities. There is an increasing interest in the use of dance as part of rehabilitation for individuals with ASD. However, it is not clear how dance can influence on ASD symptoms. And few studies have measured and compared the outcomes of multiple studies. This study was aimed to provide a more comprehensive perspective of the efficacy of dance practice on ASD symptoms by conducting a systematic review with meta-analysis.

**Methods:** 
The electronic databases PubMed, EBSCO, MEDLINE, Cochrane and PsycINFO were searched for relevant studies reporting on the effects of dance on ASD symptoms. Only randomized controlled trials (RCTs) and non-randomized controlled studies were included in this review. Two review authors independently performed literature search, data extraction, and study quality assessment. Effect sizes for ASD symptoms were expressed as standardized mean differences (SMD) with 95% confidence intervals.

**Results:** 
Seven eligible studies were included for meta-analysis. Dance interventions varied in frequency (1-2 sessions/week), time (40 -90 min), duration (7 -17 weeks) and type. As compared to control groups, dance practice showed significant alleviation of overall symptoms of ASD (-1.48 points, CI-2.55 to -0.42 points, p = 0.006, I2 = 75%) and improvement in social interaction (0.88, CI 0.46 to 1.30, p &lt; 0.0001, I2 = 0%), but no significant effect on empathy (0.09, CI -0.25 to 0.42, p = 0.61, I2 = 2%).

**Conclusions:** 
Dance probably alleviate the negative symptoms and social deficits of individuals with ASD. However, little difference is found in empathy. Further research and studies are needed to determine the optimal dose and if dance results in greater benefits than other types of physical activity.
AN  - WOS:000782962800012
AU  - Chen,
AU  - T.
AU  - T.
AU  - Wen,
AU  - R.
AU  - Liu,
AU  - H.
AU  - Q.
AU  - Zhong,
AU  - X.
AU  - K.
AU  - Jiang,
AU  - C.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.ctcp.2022.101565
L1  - internal-pdf://0345314774/Dance intervention for negative symptoms-2022.pdf
PY  - 2022
SP  - 10
T2  - Complementary Therapies in Clinical Practice
TI  - Dance intervention for negative symptoms in individuals with autism spectrum disorder: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000782962800012
UR  - https://www.sciencedirect.com/science/article/pii/S1744388122000330?via%3Dihub
VL  - 47
ER  -
TY  - JOUR
AB  - The aims of the present meta-analysis were to (1) examine long-term effects of universal secondary school-based interventions on a broad range of competencies and problems and (2) analyze which intervention components were related to stronger or weaker intervention effects at follow-up. Fifty-four studies of controlled evaluations (283 effect sizes) reporting on 52 unique interventions were included. Long-term intervention effects were significant but small; effect sizes ranged from .08 to .23 in the intrapersonal domain (i.e., subjective psychological functioning) and from .10 to .19 in the interpersonal domain (i.e., social functioning). Intervention components were generally related to effects on specific outcomes. Some components (e.g., group discussions) were even related to both stronger and weaker effects depending on the assessed outcome. Moreover, components associated with long-term effects differed from those associated with short-term effects. Our findings underscore the importance of carefully selecting components to foster long-term development on specific outcomes.PROSPERO registration number: CRD42019137981. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-87515-001
AU  - Mertens,
AU  - E.
AU  - Dekovic,
AU  - M.
AU  - van
AU  - Londen,
AU  - M.
AU  - Spitzer,
AU  - J.
AU  - Reitz,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-022-00406-3
L1  - internal-pdf://3472066109/Mertens-2022-Components related to long-term e.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Clinical Child and Family Psychology Review
TI  - Components related to long-term effects in the intra- and interpersonal domains: A meta-analysis of universal school-based interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-87515-001
UR  - https://link.springer.com/content/pdf/10.1007/s10567-022-00406-3.pdf
ER  -
TY  - JOUR
AB  - OBJECTIVE: The aim of this systematic review and meta-analysis was to analyze the characteristics and effectiveness of technology-based interventions in improving children sleep. 

METHODS: PubMed, Embase, PsycInfo, CENTRAL and Web of Science were searched to identify research articles published until 11 August 2021. The protocol for this study was registered with PROSPERO (CRD42021272348). Articles screening, data extraction and quality assessment were carried out by two independent reviewers. 

RESULTS: In total, the search generated 4597 studies. Of these, 15 studies (8 RCTs, 1 non-randomized control study and 6 pre-post studies) met our inclusion criteria. The meta-analysis indicated that technology-based interventions significantly increased the TST (SMD = 0.21, 95% CI = 0.06, 0.37; P = 0.007) and SE (SMD = 0.52, 95% CI = 0.17, 0.87; P = 0.003), and significantly decreased the SOL (SMD = -0.30, 95% CI = -0.47, -0.12; P = 0.001) and WASO (SMD = -0.33, 95% CI = -0.59, -0.07; P = 0.012). 

CONCLUSION: This systematic review and meta-analysis suggests that technology-based interventions may be effective at improving children sleep due to the advantages of online intervention. Further researches are needed to establish which technology components are most effective in improving children sleep, as well as explore better methods for increasing consistency of participation and accuracy of outcome evaluation.
AN  - 35305528
AU  - Zhu,
AU  - H.
AU  - Xiao,
AU  - L.
AU  - Tu,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.sleep.2022.02.013
L1  - internal-pdf://3927470971/Effectiveness of technology-based interve-2022.pdf
PY  - 2022
SP  - 141-150
T2  - Sleep Medicine
TI  - Effectiveness of technology-based interventions for improving sleep among children: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=35305528
UR  - https://www.sciencedirect.com/science/article/pii/S1389945722000570?via%3Dihub
VL  - 91
ER  -
TY  - JOUR
AB  - BACKGROUND: Exposure and response prevention (ERP) is a form of cognitive behavioral therapy that can effectively relieve obsessive-compulsive symptoms and tic symptoms in patients with obsessive-compulsive disorder (OCD) and Tourette syndrome (TS). However, the effect size of ERP-based therapy is still unclear. 

METHODS: In this study, we performed a meta-analysis to identify the efficacy of ERP-based therapy for individuals with OCD and TS. The standard mean difference (SMD) with a 95% confidence interval (CI) was calculated to assess the effect size of the efficacy for ERP-based therapy. We used subgroup and meta-regression analyses to explore the heterogeneity of the pooled SMD of ERP-based therapy for OCD. We also summarized the neuroimaging studies for ERP-based therapy for OCD. This meta-analysis was registered within the International Platform of Registered Systematic Review and Meta-analysis Protocols (number: INPLASY2021120112). 

RESULTS: A total of 18 studies including a total of 1057 patients with OCD and 3 studies including 267 with TS/chronic tic disorder were identified. We did not observe any indication of publication bias using Egger&#039;s funnel plot (p = 0.41). We observed a small-to-medium effect size of ERP for both OCD (SMD = -0.27, 95% CI: -0.53 to -0.01) and TS/chronic tic disorder (SMD = -0.35, 95% CI: -0.59 to -0.1). We found no heterogeneity of ERP-based therapy for OCD between the ERP-based therapy subgroup and medicine subgroup in the subgroup analysis (p = 0.72). We found no heterogeneity of ERP-based therapy for OCD between the child subgroup and adult subgroup in the subgroup analysis (p = 0.37). We used meta-regression analysis to identify the heterogeneity of ERP-based therapy for OCD and found that the sessions of therapy and publication year did not account for any significant heterogeneity (p &gt; 0.05). The neurological mechanism of EPR-based therapy is unclear, but it may lie in changes in the prefrontal cortex and anterior cingulate cortex. 

CONCLUSIONS: In conclusion, we found that ERP-based therapy is effective for patients with OCD and TS/chronic tic disorder. We suggest a combination with other therapies and the development of online ERP services that might prove a promising new direction for healthcare providers.
AN  - 35633178
AU  - Yan,
AU  - J.
AU  - Cui,
AU  - L.
AU  - Wang,
AU  - M.
AU  - Cui,
AU  - Y.
AU  - Li,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.31083/j.jin2103097
L1  - internal-pdf://2571322316/The Efficacy and Neural Correlates of ERP-2022.pdf
PY  - 2022
SP  - 97
T2  - Journal of Integrative Neuroscience
TI  - The Efficacy and Neural Correlates of ERP-based Therapy for OCD &amp; TS: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=35633178
UR  - https://api.imrpress.com/sci/redirect/article/pdf?journal=JIN&amp;volumeCode=21&amp;issueCode=3&amp;doi=10.31083/j.jin2103097
VL  - 21
ER  -
TY  - JOUR
AB  - Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that negatively affects the inattention, disorganization, and/or hyperactivity-impulsivity in children and adolescents who suffer from it, included cases being reported that continue into adulthood. This disorder impairs social, academic, emotional, psychological, and health system functioning due to its high cost of treatment. 

The present systematic review aims to analyze the effects of physical activity, exercise, and sports on the executive function in children and adolescents diagnosed with ADHD through the scientific literature. 

The results show that the practice of physical activity, exercise, or sport produces improvements in executive function in children and adolescents diagnosed with ADHD, mainly through aerobic exercise. A 20 min session of physical activity, sport, or exercise leads to improvements in executive functions in children and adolescents with ADHD. 

It can be concluded that the practice of physical activity, exercise, and sport generate improvements on executive functions in children and adolescents with ADHD, mainly through aerobic exercise.
AN  - 35049535
AU  - Montalva-Valenzuela,
AU  - F.
AU  - Andrades-Ramirez,
AU  - O.
AU  - Castillo-Paredes,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ejihpe12010006
L1  - internal-pdf://0314352275/Effects of Physical Activity, Exercise an-2022.pdf
PY  - 2022
SP  - 61-76
T2  - European Journal of Investigation in Health Psychology &amp; Education
TI  - Effects of Physical Activity, Exercise and Sport on Executive Function in Young People with Attention Deficit Hyperactivity Disorder: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35049535
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363537/pdf/nihms-1557548.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **Background:** 
Recently, the United States Food and Drug Administration (USFDA) approved viloxazine extended-release (ER) to manage attention-deficit hyperactivity disorder (ADHD) in pediatric patients of 6-17 years of age. 

**Objective:** 
To perform a meta-analysis to determine the safety and efficacy of viloxazine ER in the management of ADHD. 

**Data Source and Methods:** 
A literature search was performed through the databases Cochrane Library, PubMed, and clinicaltrials.gov, for a period from inception to August 2021, with the keywords: viloxazine, SPN-812, ADHD, and randomized clinical trials. The randomized controlled trials published in English language that analyzed the efficacy and safety were included. The risk of bias (RoB) was assessed by RoB tool. The outcomes included in this study were the proportion of patients with a 50% reduction in ADHD-Rating Scale-5 (ADHD-RS-5 responders) and improvement in CGI-I scale and the proportion of patients with at least one adverse event, the incidence of somnolence and Serious Adverse Events (SAEs). 

**Results:** 
This meta-analysis includes 1605 patients from five randomized clinical trials; all of the trials were at low risk of bias. Viloxazine group had more ADHD-RS-5 responders as compared to placebo; RR = 1.62; 95% CI = 1.36-1.93; P = &lt;.00001. Significantly higher number of patients showed improved CGI-I score; RR = 1.53; 95% CI = 1.32-1.78; P = &lt;.00001. A higher proportion of patients was observed with at least one adverse event (RR = 1.52; 95% CI = 1.24-1.85; P = &lt;.0001), and somnolence (RR = 3.93; 95% CI = 2.11-7.31; P = &lt;.0001) in viloxazine group. The incidence of SAEs was more in viloxazine group (RR = 2.98; 95% CI = .67-13.3; P = .15). 

**Conclusions:** 
Viloxazine was found to be significantly superior to placebo in both efficacy outcomes. Adverse events and somnolence were significantly more than the placebo. The incidence was SAEs was more in the viloxazine group but was not statistically significant.
AN  - 35615643
AU  - Singh,
AU  - A.
AU  - Balasundaram,
AU  - M.
AU  - K.
AU  - Singh,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/11795735221092522
L1  - internal-pdf://4150343731/Viloxazine for Attention-Deficit Hyperact-2022.pdf
PY  - 2022
SP  - 11795735221092522
T2  - Journal of Central Nervous System Disease
TI  - Viloxazine for Attention-Deficit Hyperactivity Disorder: A Systematic Review and Meta-analysis of Randomized Clinical Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35615643
UR  - https://journals.sagepub.com/doi/pdf/10.1177/11795735221092522
VL  - 14
ER  -
TY  - JOUR
AB  - BACKGROUND: Psychological treatments for common mental disorders are increasingly being delivered remotely via the internet. Evidence suggests that internet-delivered cognitive behavioural therapy (iCBT) is superior to waitlist. However, the benefits are unclear of using this treatment modality as an add-on to treatment as usual (TAU) in regular healthcare. 

METHODS: The literature was systematically searched up to August 2021 for randomized trials of internet-delivered psychological treatments using TAU as the comparator. Eligible participants were diagnosed with depressive, anxiety, obsessive-compulsive, or trauma- and stress-related disorders. Outcomes of interest were symptoms, functioning, quality of life, healthcare utilization, and negative effects. Results were synthesized using random-effects meta-analyses. Quality of evidence was assessed using GRADE. 

RESULTS: The included studies evaluated iCBT for adults with depression (k = 9), depressive or anxiety disorders (k = 4), and post-traumatic stress disorder (k = 2) and were conducted in primary care or similar settings. For depression, low-certainty evidence suggested beneficial short-term effects on symptoms (g = -0.23; 95 % CI: = -0.37, -0.09), response rate (OR = 2.46; 1.31, 4.64), and remission (OR = 1.70; 1.19, 2.42;). The certainty of evidence was very low for long-term effects, other outcomes, and other disorders. 

LIMITATIONS: TAU varied across studies and was often insufficiently described. 

CONCLUSIONS: iCBT as a complement to usual care for adult with depression may result in a small incremental effect, which potentially could be clinically important. Studies are lacking for several common disorders and for children, adolescents, and the elderly. More robust studies of long-term effects are also needed, to better inform clinical decision-making.
AN  - 36400149
AU  - Jonsson,
AU  - U.
AU  - Linton,
AU  - S.
AU  - J.
AU  - Ybrandt,
AU  - H.
AU  - Ringborg,
AU  - A.
AU  - Leander,
AU  - L.
AU  - Moberg,
AU  - K.
AU  - Hultcrantz,
AU  - M.
AU  - Arnberg,
AU  - F.
AU  - K.
DB  - Alerts 6_2022.enl
DO  - /10.1016/j.jad.2022.11.036
L1  - internal-pdf://0746768668/Jonsson_2022.pdf
PY  - 2022
SP  - 221-234
T2  - Journal of Affective Disorders
TI  - Internet-delivered psychological treatment as an add-on to treatment as usual for common mental disorders: A systematic review with meta-analysis of randomized trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36400149
VL  - 322
ER  -
TY  - JOUR
AB  - **Background**
Attention Deficit Hyperactivity Disorder (ADHD) can co‐occur in up to 40% of people with epilepsy. There is debate about the efficacy and tolerability of stimulant and non‐stimulant drugs used to treat people with ADHD and co‐occurring epilepsy.

**Objectives**
To assess the effect of stimulant and non‐stimulant drugs on children and adults with ADHD and co‐occurring epilepsy in terms of seizure frequency and drug withdrawal rates (primary objectives), as well as seizure severity, ADHD symptoms, cognitive state, general behaviour, quality of life, and adverse effects profile (secondary objectives).

**Search methods**
We searched the following databases on 12 October 2020: Cochrane Register of Studies (CRS Web), MEDLINE (Ovid, 1946 to 9 October 2020), CINAHL Plus (EBSCOhost, 1937 onwards). There were no language restrictions. CRS Web includes randomised or quasi‐randomised controlled trials from PubMed, Embase, ClinicalTrials.gov, the World Health Organization International Clinical Trials Registry Platform (ICTRP), the Cochrane Central Register of Controlled Trials (CENTRAL), and the Specialised Registers of Cochrane Review Groups including Epilepsy. 

**Selection criteria**
We included randomised controlled trials of stimulant and non‐stimulant drugs for people of any age, gender or ethnicity with ADHD and co‐occurring epilepsy.

**Data collection and analysis**
We selected articles and extracted data according to predefined criteria. We conducted primary analysis on an intention‐to‐treat basis. We presented outcomes as risk ratios (RRs) with 95% confidence intervals (CIs), except for individual adverse effects where we quoted 99% CIs. We conducted best‐ and worst‐case sensitivity analyses to deal with missing data. We carried out a risk of bias assessment for each included study using the Cochrane risk of bias tool and assessed the overall certainty of evidence using the GRADE approach.

**Main results**
We identified two studies that matched our inclusion criteria: a USA study compared different doses of the stimulant drug osmotic‐release oral system methylphenidate (OROS‐MPH) with a placebo in 33 children (mean age 10.5 &plusmn; 3.0 years), and an Iranian study compared the non‐stimulant drug omega‐3 taken in conjunction with risperidone and usual anti‐seizure medication (ASM) with risperidone and ASM only in 61 children (mean age 9.24 &plusmn; 0.15 years). All children were diagnosed with epilepsy and ADHD according to International League Against Epilepsy and Diagnostic and Statistical Manual of Mental Disorders, fourth edition, criteria, respectively. We assessed both studies to be at low risk of detection and reporting biases, but assessments varied from low to high risk of bias for all other domains.

OROS‐MPH
No participant taking OROS‐MPH experienced significant worsening of epilepsy, defined as: 1. a doubling of the highest 14‐day or highest two‐day seizure rate observed during the 12 months before the trial; 2. a generalised tonic‐clonic seizure if none had been experienced in the previous two years; or 3. a clinically meaningful intensification in seizure duration or severity (33 participants, 1 study; low‐certainty evidence). However, higher doses of OROS‐MPH predicted an increased daily risk of a seizure (P &lt; 0.001; 33 participants, 1 study; low‐certainty evidence). OROS‐MPH had a larger proportion of participants receiving &#039;much improved&#039; or &#039;very much improved&#039; scores for ADHD symptoms on the Clinical Global Impressions for ADHD‐Improvement tool (33 participants, 1 study; low‐certainty evidence). OROS‐MPH also had a larger proportion of people withdrawing from treatment (RR 2.80; 95% CI 1.14 to 6.89; 33 participants, 1 study; moderate‐certainty evidence).

Omega‐3
Omega‐3 with risperidone and ASM were associated with a reduction in mean seizure frequency by 6.6 seizures per month (95% CI 4.24 to 8.96; 56 participants, 1 study; low‐certainty evidence) and an increase in the proportion of people achieving 50% or greater reduction in monthly seizure frequency (RR 2.79, 95% CI 0.84 to 9.24; 56 participants, 1 study; low‐certainty evidence) compared to people on risperidone and ASM alone. Omega‐3 with risperidone and ASM also had a smaller proportion of people withdrawing from treatment (RR 0.65, 95% CI 0.12 to 3.59; 61 participants, 1 study; low‐certainty evidence) but a larger proportion of people experiencing adverse drug events (RR 1.40, 95% CI 0.44 to 4.42; 56 participants, 1 study; low‐certainty evidence) compared to people on risperidone and ASM alone.

**Authors&#039; conclusions**
In children with a dual‐diagnosis of epilepsy and ADHD, there is some evidence that use of the stimulant drug OROS‐MPH is not associated with significant worsening of epilepsy, but higher doses of it may be associated with increased daily risk of seizures; the evidence is of low‐certainty. OROS‐MPH is also associated with improvement in ADHD symptoms. However, this treatment was also associated with a large proportion of treatment withdrawal compared to placebo. In relation to the non‐stimulant drug omega‐3, there is some evidence for reduction in seizure frequency in children who are also on risperidone and ASM, compared to children who are on risperidone and ASM alone. Evidence is inconclusive whether omega‐3 increases or decreases the risk of adverse drug events.

We identified only two studies &ndash; one each for OROS‐MPH and omega‐3 &ndash; with low to high risk of bias. We assessed the overall certainty of evidence for the outcomes of both OROS‐MPH and omega‐3 as low to moderate.

More studies are needed. Future studies should include: 1. adult participants; 2. a wider variety of stimulant and non‐stimulant drugs, such as amphetamines and atomoxetine, respectively; and 3. additional important outcomes, such as seizure‐related hospitalisations and quality of life. Clusters of studies which assess the same drug &ndash; and those that build upon the evidence base presented in this review on OROS‐MPH and omega‐3 &ndash; are needed to allow for meta‐analysis of outcomes.
AU  - Eaton,
AU  - C.
AU  - Yong,
AU  - K.
AU  - Walter,
AU  - V.
AU  - Mbizvo,
AU  - G.
AU  - K.
AU  - Rhodes,
AU  - S.
AU  - Chin,
AU  - R.
AU  - FM.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013136.pub2
L1  - internal-pdf://0970577804/Eaton_et_al-2022-Cochrane_Database_of_Systemat.pdf
PY  - 2022
T2  - Cochrane Database of Systematic Reviews
TI  - Stimulant and non‐stimulant drug therapy for people with attention deficit hyperactivity disorder and epilepsy
ER  -
TY  - JOUR
AB  - Youth depression is an impairing pediatric condition for which psychotherapy effects are modest. Can outcomes be improved by treatments that address the family context, as proposed in practice parameters of the American Academy of Child and Adolescent Psychiatry? To find out, we searched five decades of research for randomized controlled trials testing family-based interventions; 11 trials were found for ages 4-18 years. Using robust variance estimation, we obtained estimates of effect size (ES) and tested candidate moderators that might explain variation in ES. Overall pooled ES of the studies was 0.33 at posttreatment, similar to that reported for all youth depression treatments in three prior meta-analyses (i.e., 0.36, 0.30, and 0.29), but higher for adolescents (ages &gt;= 13, 0.50) than children (0.04). Taken together, our findings do not show superior outcomes for family-based interventions, and raise questions about how much confidence can be placed in the evidence base to date. The small number of relevant studies in more than five decades, together with the publication bias and risk of bias concerns, highlights the need for more trials testing family-based treatment, and for pre-registered reports, publicly-available preprints, and other mechanisms for improving the dissemination of completed research.
AN  - 35616765
AU  - Eckshtain,
AU  - D.
AU  - Horn,
AU  - R.
AU  - Weisz,
AU  - J.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10578-022-01375-y
L1  - internal-pdf://2275023310/Family-Based Interventions for Youth Depr-2022.pdf
PY  - 2022
SP  - 26
T2  - Child Psychiatry &amp; Human Development
TI  - Family-Based Interventions for Youth Depression: Meta-Analysis of Randomized Clinical Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35616765
UR  - https://link.springer.com/article/10.1007/s10578-022-01375-y
UR  - https://link.springer.com/content/pdf/10.1007/s10578-022-01375-y.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - BACKGROUND: Social support is a protective factor for siblings of children with neurodevelopmental disorders. 

AIMS: We reviewed studies on social support received by siblings of children with neurodevelopmental disorders. 

METHODS AND PROCEDURES: We conducted a pre-registered systematic review (CRD42020207686), searching PsycINFO, MEDLINE, Web of Science, and Scopus. 

OUTCOMES AND RESULTS: Fifteen articles were eligible for the review, 13 of which used cross-sectional designs. Two studies investigated sibling social support after an intervention. Multiple variables were negatively related to social support (e.g., sibling depression, loneliness, stress). Variables that were positively related to social support included prosocial behavior, competence (academic, social, and activity-related), problem-focused coping, and family quality of life. Potential moderators of the relationship between social support and psychosocial adjustment included the type of disorder of the affected sibling and the type of social support provider. We conclude with an overview of the reliability and validity of the seven social support measurements used across the studies. 

CONCLUSIONS AND IMPLICATIONS: Lower levels of social support are associated with more negative psychosocial adjustment among siblings of children with neurodevelopmental disorders. We encourage future researchers to further investigate ways to increase social support for siblings to improve outcomes.
AN  - 35468570
AU  - Kirchhofer,
AU  - S.
AU  - M.
AU  - Orm,
AU  - S.
AU  - Haukeland,
AU  - Y.
AU  - B.
AU  - Fredriksen,
AU  - T.
AU  - Wakefield,
AU  - C.
AU  - E.
AU  - Fjermestad,
AU  - K.
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ridd.2022.104234
L1  - internal-pdf://3638187004/A systematic review of social support for-2022.pdf
PY  - 2022
SP  - 104234
T2  - Research in Developmental Disabilities
TI  - A systematic review of social support for siblings of children with neurodevelopmental disorders
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35468570
UR  - https://www.sciencedirect.com/science/article/pii/S0891422222000646?via%3Dihub
VL  - 126
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis aims to synthesize the efficacy of culturally sensitive prevention programs for substance use outcomes among U.S. adolescents of color (aged 11 to 18 years old) and explore whether the intervention effects vary by participant and intervention characteristics. 

Eight electronic databases and grey literature were searched for eligible randomized controlled trials through September 2022. Robust variance estimation in meta-regression was used to synthesize treatment effect size estimates and to conduct moderator analysis. 

After screening, 30 unique studies were included. The average treatment effect size across all substance use outcomes (including 221 effect sizes) was Hedges&#039;s g = -0.20, 95% CI = [-0.24, -0.16]. The synthesized effect sizes were statistically significant across types of substances (alcohol, cigarette, marijuana, illicit and other drugs, and unspecified substance use), racial/ethnic groups (Hispanic, Black, and Native American), and different follow-ups (0-12 months, &gt;12 months). Very few studies reported substance use consequences as outcomes and the synthesized effect size was non-significant. Meta-regression findings suggest that the intervention effects may vary based on the type of substance.

 This meta-analysis found supportive evidence of culturally sensitive prevention programs&#039; efficacy in preventing or reducing substance use among Black, Hispanic, and Native American adolescents. More substance use prevention efforts and evidence is needed for Asian American, Pacific Islander, and multiracial adolescents.
AD  - Bo, Ai. Helen Bader School of Social Welfare, Department of Social Work, University of Wisconsin-Milwaukee, Milwaukee, WI, United States. Electronic address: aibo@uwm.edu.Goings, Trenette Clark. School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.Evans, Caroline B R. School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.Sharma, Anjalee. School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.Jennings, Zoe. School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.Durand, Brenna. Helen Bader School of Social Welfare, Department of Criminal Justice &amp; Criminology, University of Wisconsin-Milwaukee, WI, United States.Bardeen, Angela. Research and Instructional Services, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.Murray-Lichtman, Andrea. School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
AN  - 36495737
AU  - Bo,
AU  - A.
AU  - Goings,
AU  - T.
AU  - C.
AU  - Evans,
AU  - C.
AU  - B.
AU  - R.
AU  - Sharma,
AU  - A.
AU  - Jennings,
AU  - Z.
AU  - Durand,
AU  - B.
AU  - Bardeen,
AU  - A.
AU  - Murray-Lichtman,
AU  - A.
DA  - Nov 30
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.cpr.2022.102233
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://1994411753/1-s2.0-S0272735822001180-main.cleaned.pdf
LA  - English
M3  - Review
N1  - Bo, AiGoings, Trenette ClarkEvans, Caroline B RSharma, AnjaleeJennings, ZoeDurand, BrennaBardeen, AngelaMurray-Lichtman, AndreaS0272-7358(22)00118-0
PY  - 2022
SP  - 102233
T2  - Clinical Psychology Review
TI  - Culturally sensitive prevention programs for substance use among adolescents of color: A systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36495737
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36495737&amp;id=doi:10.1016%2Fj.cpr.2022.102233&amp;issn=0272-7358&amp;isbn=&amp;volume=99&amp;issue=&amp;spage=102233&amp;pages=102233&amp;date=2022&amp;title=Clinical+Psychology+Review&amp;atitle=Culturally+sensitive+prevention+programs+for+substance+use+among+adolescents+of+color%3A+A+systematic+review+and+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Bo&amp;pid=%3Cauthor%3EBo+A%3C%2Fauthor%3E%3CAN%3E36495737%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 99
ER  -
TY  - JOUR
AB  - **Background:** 
Anorexia is a common obstacle to adequate nutrition in childhood, a critical period for physical growth. East Asian traditional medicine treatment modalities including herbal medicine (HM) a re considered an attractive therapeutic option, especially in East Asian countries. The purpose of this systematic review was to comprehensively examine the efficacy and safety of HM for anorexia in children. 

**Method(s):** 
A total of 12 electronic databases from their inception date to June 2021 were searched for randomized controlled trials (RCTs) assessing the efficacy of HM for the treatment of anorexia in children. The primary outcome was an improvement in anorexia clinical symptoms after treatment. In this meta-analysis, continuous and binary outcomes were assessed, and the data are presented as the mean difference or standardized mean difference and risk ratio (RR) with their 95% confidence intervals (CIs). The risk of bias and quality of evidence were assessed using the Cochrane Collaboration&#039;s risk of bias tool and Grading of Recommendations, Assessment, Development, and Evaluations tool. 

**Result(s):** 
A total of 205 RCTs were included. A comparison of HM with placebo revealed that the total effective rate based on anorexia symptom improvement was significantly higher in the HM group (RR 1.58, 95% CI 1.34, 1.85). In comparison with controls, HM as monotherapy or adjunctive therapy to dietary supplements or conventional medications led to significant improvements in anorexia symptoms, body measurements, levels of blood biomarkers related to gastrointestinal function, and nutrition indices, with a lower recurrence rate of anorexia. No serious adverse events related to HM were reported. The risk of bias of the included studies was generally unclear, and the quality of evidence was generally low to moderate. 

**Conclusion(s):** 
Our study showed that HM could improve clinical symptoms, some anthropometric outcomes, and some biological markers related to appetite and growth in children with anorexia. However, considering the high risk of bias of the included studies and the heterogeneity of the HMs used, future research should focus on the use of standardized HMs and the implementation of methodologically robust clinical trials. 

Systematic Review Registration: https://www.crd.york.ac.uk/prosperodisplay_record.php?ID=CRD42021274376, identifier CRD42021274376. Copyright &copy; 2022 Lee, Kwon, Lee and Chang.
AN  - 2015621906
AU  - Lee,
AU  - B.
AU  - Kwon,
AU  - C.
AU  - Y.
AU  - Lee,
AU  - S.
AU  - H.
AU  - Chang,
AU  - G.
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fphar.2022.839668
L1  - internal-pdf://2760463856/Herbal Medicine for the Treatment of Anor-2022.pdf
PY  - 2022
T2  - Frontiers in Pharmacology
TI  - Herbal Medicine for the Treatment of Anorexia in Children: A Systematic Review and Meta-Analysis
UR  - http://www.frontiersin.org/Pharmacology
VL  - 13 (no pagination)
ER  -
TY  - JOUR
AB  - The aim of the present systematic review was to discuss the reported efficacy of executive functioning training techniques among adolescents. A systematic review of the literature was conducted to retrieve and consolidate findings from articles evaluating executive functioning training techniques among adolescents. A total of 26 articles were located that examined the role of executive functioning training techniques among adolescents (age 10-19 years). Articles retrieved enabled comparison across psychiatric and medical diagnoses including attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), as well as adolescents with physical health concerns. Results revealed that among typically developing adolescents, executive functioning training was non-significant or yielded small effect size improvements in executive functioning as measured by behavioral and neuroimaging tasks among 62.5% of studies reviewed. In contrast, in those with medical conditions, ASD, ADHD, and conduct disorder, all but two studies reviewed yielded a medium to large effect size, supporting the effectiveness of EF training. Future research is needed to identify the long-term efficacy of these treatments, as well as their generalizability to real-world conditions.
AN  - WOS:000834936500001
AU  - Shepard,
AU  - E.
AU  - Sweeney,
AU  - C.
AU  - Thompson,
AU  - L.
AU  - Jacobs,
AU  - S.
AU  - Grimm,
AU  - J.
AU  - Weyandt,
AU  - L.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1080/21622965.2022.2106436
L1  - internal-pdf://1624344734/Effectiveness of executive functioning trainin.pdf
PY  - 2022
SP  - 17
T2  - Applied Neuropsychology-Child
TI  - Effectiveness of executive functioning training among heterogeneous adolescent samples: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000834936500001
UR  - https://www.tandfonline.com/doi/full/10.1080/21622965.2022.2106436
ER  -
TY  - JOUR
AB  - **Background/Objective:** 
Literature shows that there is a circular relationship between children&#039;s ADHD-related behaviors and parenting stress. This systematic review and meta-analysis aimed to understand if mindfulness parent trainings have benefits for both parenting stress and the problem behaviors in children with ADHD. 

**Method(s):** 
Five databases, CINAHL, Embase, PsycINFO, PubMED, and Web of Science, were searched. Within-group effects at post-treatment and follow-up assessment, and between-group effects at post-treatment were analyzed. Effect sizes (Hedges&#039; g) were also calculated. 

**Result(s):** 
Ten studies (5 RCTs and 5 non-RCTs) met the selection criteria and were selected for systematic review, and nine of them were included for meta-analysis. Among these 10 studies, five studies involved mindfulness training for both parents and children, while the other five studies involved mindfulness training for parents only. Within-group effects at post-treatment were small-to-large for all outcomes. Hedges&#039; g ranged between -0.17 [95% CI (-0.98, 0.64)] and 4.70 [95% CI (3.59, 5.81)] for parenting stress; 0.17 [95% CI (-0.03, 0.37)] and 4.03 [95% CI (2.97, 5.09)] for children&#039;s problem behaviors; and 0.20 [95% CI (-0.10, 0.50)] and 2.98 [95% CI (2.16, 3.80)] for children&#039;s ADHD symptoms. Between-group comparisons showed mindfulness parent training was superior to other active controls on all outcomes. 

**Conclusion(s):** 
Findings suggest that mindfulness parent training may be beneficial for parenting stress and children&#039;s ADHD-related behaviors, and due to the small number of studies reviewed, cautions should be taken when interpreting the results. Copyright &copy; The Author(s) 2022.
AN  - 2015214412
AU  - Lee,
AU  - C.
AU  - S.
AU  - C.
AU  - Ng,
AU  - K.
AU  - H.
AU  - Chan,
AU  - P.
AU  - C.
AU  - K.
AU  - Peng,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/15691861211073826
L1  - internal-pdf://2313226862/Effectiveness of mindfulness parent train-2022.pdf
PY  - 2022
T2  - Hong Kong Journal of Occupational Therapy.
TI  - Effectiveness of mindfulness parent training on parenting stress and children&#039;s ADHD-related behaviors: A systematic review and meta-analysis
UR  - https://journals.sagepub.com/home/HJO
ER  -
TY  - JOUR
AB  - OBJECTIVE: Disruptive behavior disorders (DBDs) represent a common motive for referral among youths. This meta-analysis aimed at estimating the efficacy of psychosocial interventions for DBD adolescents. 

METHOD: A PRISMA-compliant systematic review of MEDLINE/PubMED/PsycINFO/Cochrane Central Register of Controlled Trials was conducted. Eligible studies were randomized controlled trials (RCTs) administering psychosocial interventions to DBD adolescents, published before April 5, 2020. From the initial set of 6,006 records, 17 RCTs involving 18 cohorts (16 publications) were subjected to a random-effect meta-analysis (involving sensitivity, subgroup, and meta-regression analyses). Primary and secondary outcomes were externalizing symptoms at RCT endpoint (i.e., standardized mean difference [SMD]) and acceptability (drop-out odds ratio [OR]), respectively. Risk of bias was assessed using the Risk of Bias 2 tool. 

RESULTS: Seventeen RCTs, involving 1,954 adolescents, were included. Mean age was 14.09 (SD 1.33) years; 61% were male. Mean RCT duration was 12 weeks, with a mean follow-up of 8 (SD 3.98) months. Concern over risk of bias emerged in 12 studies, with high concern in 6. Psychosocial interventions had a large effect size at RCT endpoint (SMD=0.98, 95%CI -0.55 to -1.38, k=18) and were acceptable (drop-out OR=1.29, 95%CI 0.62-2.70, k=13). However, this beneficial effect did not persist at follow-up (SMD=-0.36, 95%CI 0.06 to -0.78, k=10). Family format was the most effective variable. No other clinically significant moderator was found. 

CONCLUSION: Psychosocial interventions involving the families of DBD adolescents are effective and acceptable in the short term. Future studies should focus on strategies to achieve their long-term efficacy.
AN  - 35551985
AU  - Boldrini,
AU  - T.
AU  - Ghiandoni,
AU  - V.
AU  - Mancinelli,
AU  - E.
AU  - Salcuni,
AU  - S.
AU  - Solmi,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2022.05.002
L1  - internal-pdf://1332351142/Systematic Review and Meta-analysis_ Psyc-2022.pdf
PY  - 2022
SP  - 08
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Systematic Review and Meta-analysis: Psychosocial Treatments for Disruptive Behavior Symptoms and Disorders in Adolescence
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35551985
UR  - https://www.sciencedirect.com/science/article/pii/S0890856722002532?via%3Dihub
VL  - 08
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
Anorexia nervosa (AN) is a severe psychiatric disorder characterized by starvation and malnutrition, a high incidence of coexisting psychiatric conditions, and treatment resistance. The effect of pharmacotherapy has been controversial. 

**METHOD**
A systematic review was conducted for evidence of an effect of olanzapine versus placebo in adults or its effect as adjuvant treatment of AN in adolescents. 

**RESULTS**
A total of seven articles (304 patients with AN) were identified. There were four double-blind, randomized studies examining the effect of olanzapine in the treatment of AN. The mean difference in body mass index (BMI) at the end of treatment between olanzapine and placebo was 0.67 kg/m&lt;sup&gt;2&lt;/sup&gt; (95% confidence interval (CI) 0.15-1.18 kg/m&lt;sup&gt;2&lt;/sup&gt; ; p = 0.01; I&lt;sup&gt;2&lt;/sup&gt; = 0%, p for heterogeneity &lt; 0.79). The olanzapine groups showed a significant increase in BMI of 0.68 kg/m&lt;sup&gt;2&lt;/sup&gt; (95% CI 0.22-1.13 kg/m&lt;sup&gt;2&lt;/sup&gt; ; p &lt; 0.001; I&lt;sup&gt;2&lt;/sup&gt; = 0%, p for heterogeneity = 0.74) compared to the placebo groups. Only two studies examined the effect of olanzapine as adjuvant treatment in adolescents and showed an increase in BMI of 0.66 kg/m&lt;sup&gt;2&lt;/sup&gt; (95% CI -0.36 to 1.67 kg/m&lt;sup&gt;2&lt;/sup&gt; ; p = 0.21; I&lt;sup&gt;2&lt;/sup&gt; = 11%, p for heterogeneity = 0.32). 

**DISCUSSION**
Olanzapine showed efficacy in the treatment of AN with an increased BMI at the end of treatment in adults. The effect of olanzapine as adjuvant treatment in adolescents remains unclear.
AN  - 35020271
AU  - Han,
AU  - R.
AU  - Bian,
AU  - Q.
AU  - Chen,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/brb3.2498
L1  - internal-pdf://0688429185/Effectiveness of olanzapine in the treatm-2022.pdf
PY  - 2022
SP  - e2498
T2  - Brain and Behavior
TI  - Effectiveness of olanzapine in the treatment of anorexia nervosa: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35020271
UR  - https://onlinelibrary.wiley.com/doi/10.1002/brb3.2498
ER  -
TY  - JOUR
AB  - The World Health Organization currently recommends calcium supplementation for pregnant women, especially those with low calcium intakes, to reduce the risk of hypertension and preeclampsia. We aimed to evaluate the effect of this intervention on selected offspring outcomes.

A systematic search was conducted in 11 databases for published randomized controlled trials (RCTs) on the effect of maternal calcium supplementation with or without vitamin D during pregnancy on selected offspring cardiovascular, growth, and metabolic and neurodevelopmental outcomes. Screening of titles and abstracts of 3555 records and full texts of 31 records yielded six RCTs (nine reports, n = 1616). Forest plot analyses were performed if at least two studies presented comparable data on the same outcome. 

In one study (n = 591), high-dose calcium supplementation during pregnancy was associated with a decreased risk of offspring high systolic blood pressure at 5-7 years of age (risk ratio = 0.59; 95% confidence interval: 0.39-0.90). The effects of the intervention on offspring growth, metabolic, and neurodevelopmental outcomes remain unknown because of conflicting or insufficient data. High risk of attrition bias decreased the quality of the evidence. Limited available data from RCTs do not provide sufficient evidence to conclude that prenatal calcium supplementation influences offspring health outcomes beyond the newborn period.
AN  - WOS:000737278600001
AU  - Korhonen,
AU  - P.
AU  - Tihtonen,
AU  - K.
AU  - Isojarvi,
AU  - J.
AU  - Ojala,
AU  - R.
AU  - Ashorn,
AU  - U.
AU  - Ashorn,
AU  - P.
AU  - Tammela,
AU  - O.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/nyas.14729
L1  - internal-pdf://3163856383/Calcium supplementation during pregnancy and l.pdf
PY  - 2022
SP  - 16
T2  - Annals of the New York Academy of Sciences
TI  - Calcium supplementation during pregnancy and long-term offspring outcome: a systematic literature review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000737278600001
UR  - https://nyaspubs.onlinelibrary.wiley.com/doi/10.1111/nyas.14729
ER  -
TY  - JOUR
AB  - INTRODUCTION: Emotional regulation (ER) is a core variable involved in the onset and maintenance of mental health disorders; therefore, interventions targeting ER in adolescence represent a promising preventive action. The current systematic review provides a synthesis of the evidence on school-based interventions on ER in adolescent students. 

METHODS: Six electronic databases (Medline, Psychology Database, Embase, Scopus, Psychinfo, and Web of Science) were searched. The methodological quality of the included studies was assessed by the Methodological Index for Nonrandomized Studies. 

RESULTS: A total of 36 studies were identified. The interventions were based on different theoretic frameworks and focused on different components of ER. There were universal interventions that addressed the entire class, as well as interventions for a selected population of at-risk students. Only one-third of the studies were based on manualized programs. Small to moderate effect sizes were found for mental health and ER skills. Only a few studies assessed risky behaviors, and these studies showed a reduction with moderate to large effect size. Studies conducted on high-risk populations showed medium-high effect sizes on ER skills. In contrast, studies conducted on unselected samples of students showed greater variability in the outcome estimates. Acceptability analysis and attendance rates suggested that the interventions were well received by students. The lack of follow-up assessments and the absence of sample-size calculation were the most frequent methodological weaknesses. 

CONCLUSIONS: The content of the present review could be useful for professionals involved in the planning of school psychological services. Overall, the findings of the current review support the applicability and beneficial effect of school-based intervention for adolescents. Moreover, the results clearly point out the utility of a multitiered model to structure coordinated and integrated preventive interventions and to optimize resources.
AN  - 36082432
AU  - Pedrini,
AU  - L.
AU  - Meloni,
AU  - S.
AU  - Lanfredi,
AU  - M.
AU  - Rossi,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/jad.12090
L1  - internal-pdf://3495482204/Pedrini-2022-School-based interventions to imp.pdf
PY  - 2022
SP  - 08
T2  - Journal of Adolescence
TI  - School-based interventions to improve emotional regulation skills in adolescent students: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36082432
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jad.12090?download=true
VL  - 08
ER  -
TY  - JOUR
AB  - **Background:** 
Anxiety is a mental disorder characterized by apprehension, tension, uneasiness, and other related behavioral disturbances. One of the nonpharmacological treatments used for reducing anxiety is serious games, which are games that have a purpose other than entertainment. The effectiveness of serious games in alleviating anxiety has been investigated by several systematic reviews; however, they were limited by design and methodological weaknesses. 

**Objective:** 
This study aims to assess the effectiveness of serious games in alleviating anxiety by summarizing the results of previous studies and providing an up-to-date review. 

**Methods:** 
We conducted a systematic review of randomized controlled trials (RCTs). The following seven databases were searched: MEDLINE, CINAHL, PsycINFO, ACM Digital Library, IEEE Xplore, Scopus, and Google Scholar. We also conducted backward and forward reference list checking for the included studies and relevant reviews. Two reviewers independently carried out the study selection, data extraction, risk of bias assessment, and quality of evidence appraisal. We used a narrative and statistical approach, as appropriate, to synthesize the results of the included studies. 

**Results:** 
Of the 935 citations retrieved, 33 studies were included in this review. Of these, 22 RCTs were eventually included in the meta-analysis. Very low-quality evidence from 9 RCTs and 5 RCTs showed no statistically significant effect of exergames (games entailing physical exercises) on anxiety levels when compared with conventional exercises (P=.70) and no intervention (P=.27), respectively. Although 6 RCTs demonstrated a statistically and clinically significant effect of computerized cognitive behavioral therapy games on anxiety levels when compared with no intervention (P=.01), the quality of the evidence reported was low. Similarly, low-quality evidence from 3 RCTs showed a statistically and clinically significant effect of biofeedback games on anxiety levels when compared with conventional video games (P=.03). 

**Conclusions:** 
This review shows that exergames can be as effective as conventional exercises in alleviating anxiety; computerized cognitive behavioral therapy games and exergames can be more effective than no intervention, and biofeedback games can be more effective than conventional video games. However, our findings remain inconclusive, mainly because there was a high risk of bias in the individual studies included, the quality of meta-analyzed evidence was low, few studies were included in some meta-analyses, patients without anxiety were recruited in most studies, and purpose-shifted serious games were used in most studies. Therefore, serious games should be considered complementary to existing interventions. Researchers should use serious games that are designed specifically to alleviate depression, deliver other therapeutic modalities, and recruit a diverse population of patients with anxiety.
AN  - WOS:000785987000004
AU  - Abd-alrazaq,
AU  - A.
AU  - Alajlani,
AU  - M.
AU  - Alhuwail,
AU  - D.
AU  - Schneider,
AU  - J.
AU  - Akhu-Zaheya,
AU  - L.
AU  - Ahmed,
AU  - A.
AU  - Househ,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.2196/29137
L1  - internal-pdf://0356124683/The Effectiveness of Serious Games in All-2022.pdf
PY  - 2022
SP  - 22
T2  - Jmir Serious Games
TI  - The Effectiveness of Serious Games in Alleviating Anxiety: Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000785987000004
VL  - 10
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Difficulties in emotion regulation are common in adolescence and are associated with poor social and mental health outcomes. However, psychological therapies that promote adaptive emotion regulation may be inaccessible and unattractive to youth. Digital interventions may help address this need. 

OBJECTIVE: 
The aim of this systematic review and meta-analysis was to synthesize evidence on the efficacy, feasibility, and acceptability of emotion regulation digital interventions in children and early adolescents aged 8 to 14 years. 

METHODS: 
Systematic searches of Web of Science, MEDLINE, PsycINFO, EMBASE, Education Resources Information Centre, ACM Digital Library, and IEEE Xplore up to July 2020 identified 39 studies, of which 11 (28%) were included in the meta-analyses (n=2476 participants). A bespoke tool was used to assess risk of bias. 

RESULTS: 
The studies evaluated digital games (27/39, 69%), biofeedback (4/39, 10%), virtual or augmented reality (4/39, 10%), and program or multimedia (4/39, 10%) digital interventions in samples classified as diagnosed, at risk, healthy, and universal. The most consistent evidence came from digital games, which reduced negative emotional experience with a small significant effect, largely in youth at risk of anxiety (Hedges g=-0.19, 95% CI -0.34 to -0.04). In general, digital interventions tended to improve emotion regulation, but this effect was not significant (Hedges g=0.19, 95% CI -0.16 to 0.54). 

CONCLUSIONS: 
Most feasibility issues were identified in diagnosed youth, and acceptability was generally high across intervention types and samples. Although there is cause to be optimistic about digital interventions supporting the difficulties that youth experience in emotion regulation, the predominance of early-stage development studies highlights the need for more work in this area.
AN  - 35984681
AU  - Reynard,
AU  - S.
AU  - Dias,
AU  - J.
AU  - Mitic,
AU  - M.
AU  - Schrank,
AU  - B.
AU  - Woodcock,
AU  - K.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/31456
L1  - internal-pdf://0265652195/PDF.cleaned (18).pdf
PY  - 2022
SP  - e31456
T2  - Jmir Serious Games
TI  - Digital Interventions for Emotion Regulation in Children and Early Adolescents: Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35984681
VL  - 10
ER  -
TY  - JOUR
AB  - In order to propose intervention methods that can effectively improve the vocational skills of adolescents with autism spectrum disorders, meta-analysis is conducted on 16 research articles in the past twenty years focusing on single-type subjects. The intervention Tau-U effect values of related studies are calculated, and adjustment analysis is made on the subjects&#039; characteristics, intervention types, intervention methods, intervention environment, dependent variables and the degree of matching between intervention objectives and subject characteristics. The results show that the intervention effect of vocational skills of ASD adolescents is overall significant. In terms of participant characteristics, the intervention effect of high- or medium-functioning ASD adolescents was better than that of low-functioning ASD adolescents. The analysis of intervention types showed statistically significant differences, among which the audio cueing method had the strongest intervention effect, and the frequency of mobile device teaching and behavioral skills training increased significantly. The effect of multi-component interventions is the same as that of single interventions, and it shows a good trend in the past five years and has been widely employed. Vocational skill interventions promote the employment of over 10 million persons with ASD in China, which not only helps achieve their economic independence but also is an important means to improve the social happiness index. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-89710-001
AU  - Zhou,
AU  - Kun
AU  - Ma,
AU  - Siyue
AU  - Gu,
AU  - Zhiqin
AU  - Li,
AU  - Shuting
AU  - Liu,
AU  - Xinchao
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10882-022-09867-4
L1  - internal-pdf://3729494157/Zhou-2022-Meta-analysis of vocational skills i.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Journal of Developmental and Physical Disabilities
TI  - Meta-analysis of vocational skills intervention in adolescents with autism spectrum disorders
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-89710-001
UR  - https://link.springer.com/article/10.1007/s10882-022-09867-4
UR  - https://link.springer.com/content/pdf/10.1007/s10882-022-09867-4.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Interpersonal psychotherapy (IPT) has been widely used for depression. However, current studies of IPT have been restricted to depressive symptoms, and the results for improving social functioning were controversial. 

METHODS: 
A comprehensive literature search of randomized controlled trials (RCTs) was conducted through eleven databases. Data analysis was performed by RevMan5.3, and effects were summarized by using a random effects model of mean differences with 95 % confidence intervals. 

RESULTS: 
From 2443 records, eleven studies met inclusion and exclusion criteria were used for meta-analysis. The results showed that IPT had significant effects on improving social functioning (SMD: -0.53, 95 % CI: -0.80 to -0.26), reducing depression (SMD: -0.49, 95 % CI: -0.80 to -0.19) and anxiety (SMD: -0.90, 95 % CI: -1.28 to -0.52), but the effect on the overall functioning (SMD: -0.37, 95 % CI: -0.73 to -0.01) is not obvious. Moreover, subgroup analysis showed that IPT was effective in improving social functioning in adolescent depression (SMD: -0.35, 95 % CI: -0.58 to -0.13) and perinatal depression (SMD: -1.01, 95 % CI: -1.35 to -0.67), while there was no significant difference in the adult depression group (SMD: -0.39, 95 % CI: -1.05 to 0.27). 

LIMITATION: 
The blind method cannot be carried out in most studies due to the particularity of psychotherapy, heterogeneity in some results. 

CONCLUSION: 
IPT has a significant effect on improving social functioning and reducing depression and anxiety, while the effect on overall functioning requires further research. Overall, IPT is one of the effective nonpharmacological treatments for depression.
AN  - 36183821
AU  - Bian,
AU  - C.
AU  - Zhao,
AU  - W.
AU  - W.
AU  - Yan,
AU  - S.
AU  - R.
AU  - Chen,
AU  - S.
AU  - Y.
AU  - Cheng,
AU  - Y.
AU  - Zhang,
AU  - Y.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2022.09.119
L1  - internal-pdf://1125261120/1-s2.0-S0165032722011338-main.cleaned.pdf
PY  - 2022
SP  - 230-240
T2  - Journal of Affective Disorders
TI  - Effect of interpersonal psychotherapy on social functioning, overall functioning and negative emotions for depression: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36183821
VL  - 320
ER  -
TY  - JOUR
AB  - An increasing number of refugees, including children and families, suffer traumatic experiences during persecution within their country of origin, migration, and resettlement in host countries. While ample trauma interventions are offered for different cultures, little is known about the effectiveness of trauma treatment approach for refugee minors. Accordingly, this review examines trauma studies focusing on traumatized refugee children and adolescents to provide recommendations for best practices and future directions. We systematically reviewed English peer-reviewed studies on refugee children&#039;s and adolescents&#039; trauma, treatment approaches, and measurement of posttraumatic stress disorder outcomes. Only 20 experimental studies were reviewed due to a shortage of evidence in this field. A number of empirically tested trauma treatment models were identified for reducing trauma symptoms, including trauma-focused cognitive behavioral treatment, narrative exposure therapy, eye movement desensitization and reprocessing, Mein Weg (My Way), multimodal trauma-focused treatment, and art therapy. Although the effectiveness of these treatment approaches is well-established, more research with larger and more diverse samples are needed. Appropriate therapy models are also needed for this population by focusing on the psychological needs and treatments for refugee children and adolescents. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-94680-001
AU  - Genc,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.childyouth.2022.106602
L1  - internal-pdf://1959772147/1-s2.0-S0190740922002389-main.cleaned.pdf
PY  - 2022
SP  - 1-8
T2  - Children and Youth Services Review
TI  - The effectiveness of trauma treatment approaches in refugee children and adolescents: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc19&amp;AN=2022-94680-001
UR  - https://www.sciencedirect.com/science/article/pii/S0190740922002389?via%3Dihub
VL  - 141
ER  -
TY  - JOUR
AB  - **Background:** 
Attention-deficit/hyperactivity disorder (ADHD) is associated with a broad range of deficits in cognitive functions which has significant implications for quality of life. Psychostimulants are demonstrated to improve symptoms of inattention and hyperactivity/impulsivity, however, their impact on cognition remains incompletely characterized. Herein, the aim of this systematic review is to synthesize the extant literature reporting on the effects of psychostimulants on cognitive function in individuals with ADHD. 

**Method(s):** 
A systematic search of PubMed, Scopus, and Web of Science from inception to July 2021 was conducted. Additional studies were identified through Google Scholar and a manual search of the reference lists of relevant articles. Inclusion criteria were original studies that evaluated the cognitive function of individuals with ADHD taking psychostimulants drugs. We assessed the quality of the included papers using the Newcastle-Ottawa scale (NOS). 

**Result(s):** 
A total of 10 studies involving 753 subjects with ADHD and 194 healthy controls were identified and eligible for inclusion. Nine studies evaluated the impact of methylphenidate on cognitive function and one study investigated the use of lisdexamfetamine. Results indicated that attentional deficits such as memory, vigilance, divided attention, phasic and tonic alertness, and focused attention were improved in ADHD patients treated with psychostimulants. The efficacy of psychostimulants in improving other domains of cognition remains inconclusive due to conflicting evidence or insignificant findings (ie. academic performance and executive function). Overall, results indicate that psychostimulants may improve only select domains of cognition (ie. memory and attention). 

**Conclusion(s):** 
Psychostimulants are reported to improve several disparate aspects of cognition among individuals with ADHD. Further research is needed to better understand the complex relationships between cognition and behavior in ADHD, as well as the impact of medication on these distinct aspects of functioning. Further research is also needed to determine whether the pro-cognitive effect of stimulants would be transferable to other mental disorders. Copyright &copy; 2022 Elsevier Ltd
AN  - 2017256938
AU  - McKenzie,
AU  - A.
AU  - Meshkat,
AU  - S.
AU  - Lui,
AU  - L.
AU  - M.
AU  - W.
AU  - Ho,
AU  - R.
AU  - Di
AU  - Vincenzo,
AU  - J.
AU  - D.
AU  - Ceban,
AU  - F.
AU  - Cao,
AU  - B.
AU  - McIntyre,
AU  - R.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jpsychires.2022.03.018
L1  - internal-pdf://3387709522/The effects of psychostimulants on cognit-2022.pdf
PY  - 2022
SP  - 252-259
T2  - Journal of Psychiatric Research
TI  - The effects of psychostimulants on cognitive functions in individuals with attention-deficit hyperactivity disorder: A systematic review
UR  - https://www.elsevier.com/locate/jpsychires
UR  - https://www.sciencedirect.com/science/article/pii/S0022395622001406?via%3Dihub
VL  - 149
ER  -
TY  - JOUR
AB  - To investigate the effects of measurement feedback systems (MFSs) in therapy on mental health outcomes through a literature review and meta-analysis. Using a three-level modeling approach, we conducted a meta-analysis of all effect sizes from randomized controlled studies of MFSs used in the treatment of common mental health disorders. Eighty-two effect sizes were extracted from the thirty-one included studies. Analyses were performed to consider the post-treatment effects of the MFS-assisted treatment compared to treatment as usual. A separate analysis was done for the subgroup &quot;not-on-track&quot; patients as it is theorized that MFSs will be clinically useful because they make therapists aware of patients who fail to progress. MFSs had a significant effect on mental health outcomes (d = 0.14, 95% CI [0.082-0.206], p &lt; .001). Further analysis found a larger effect in patients identified as less respondent to therapy, the &quot;not-on-track&quot; group (d = 0.29, 95% CI [0.114, 0.464], p = .003). Moderation analyses indicated that the type of outcome measurement and type of feedback system used, and whether it was used for a child and youth or adult population, influenced effect sizes. MFSs seem to have a small positive effect on treatment outcomes. The effects seem to be larger for &quot;not-on-track&quot; patients, the group of patients that would usually not benefit much from treatment.
AN  - 36434313
AU  - Rognstad,
AU  - K.
AU  - Wentzel-Larsen,
AU  - T.
AU  - Neumer,
AU  - S.
AU  - P.
AU  - Kjobli,
AU  - J.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s10488-022-01236-9
L1  - internal-pdf://4008171989/Rognstad-2022-A Systematic Review and Meta-Ana.pdf
PY  - 2022
SP  - 25
T2  - Administration &amp; Policy in Mental Health
TI  - A Systematic Review and Meta-Analysis of Measurement Feedback Systems in Treatment for Common Mental Health Disorders
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36434313
UR  - https://link.springer.com/content/pdf/10.1007/s10488-022-01236-9.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - BACKGROUND: 
As comparatively few trials in subgroups of patients with schizophrenia have been done, clinicians need to know whether they can rely on the results of randomised controlled trials (RCTs) in the general population of patients with schizophrenia. We aimed to compare the efficacy and side-effects of antipsychotic drugs in different subgroups. 

METHODS: 
In this systematic review and meta-analysis, we searched reference lists of previous systematic reviews and meta-analyses, the Cochrane Schizophrenia Group&#039;s Study-Based Register (from database inception to April 27, 2020), and PubMed (from April 1, 2020 to June 14, 2021). We excluded studies in patients with stable schizophrenia (ie, relapse prevention studies), studies with a high risk of bias, and studies from mainland China due to quality concerns concerning allocation and masking methods. We included single-blind RCTs or better that assessed one or more of 16 second-generation and 18 first-generation antipsychotics in the general population of patients with schizophrenia or in one or more of the subgroups: children and adolescents (age range as defined in the original studies), patients with a first episode, patients with predominant or prominent negative symptoms, patients with comorbid substance use, patients with treatment-resistant schizophrenia, or older patients (age range as defined in the original studies). Two authors independently screened the results of the search, retrieved full-text articles, and checked the inclusion criteria. Using the Preferred Reporting Items for Systematic Reviews and Meta-analyses guideline, all parameters were extracted in duplicate. The primary outcome was change in overall symptoms. We compared drug efficacy between subgroups, by sex, schizoaffective disorder versus schizophrenia, and study origin using random-effects, inverse variance meta-analyses and random-effects subgroup tests, and meta-regression. 

FINDINGS: 
We included 537 RCTs with 76 382 participants, 26 627 (34.9%) women, 49 755 (65.1%) men, mean age 37.3 years (range of means 7.9-80.2; ethnicity data not available). 412 RCTs included patients in the general population of patients with schizophrenia, 42 included patients with treatment-resistant schizophrenia, 25 included children and adolescents, 20 included patients with their first episode, 20 included patients with predominant or prominent negative symptoms, 13 included patients with comorbid substance use, and 11 included older patients. Of 507 random-effects subgroup tests done, 46 (9%) showed a significant difference (p&lt;0.05) between subgroups, but there was no clear indication as to which drug should be used in which subgroup. 

INTERPRETATION: 
The effects of antipsychotics in various patient subgroups were usually similar to those in the general population of patients with schizophrenia, but comparably few studies contributed to the subgroups, in particular in terms of side-effects. If the evidence for treatment in a given subgroup is small, guideline makers and clinicians should consider using the results in the much better studied group of the general population of patients with schizophrenia. 

FUNDING: 
German Federal Ministry of Education and Research (Bundesministerium fur Bildung und Forschung; FKZ 01KG1508).
AN  - 36228647
AU  - Leucht,
AU  - S.
AU  - Chaimani,
AU  - A.
AU  - Krause,
AU  - M.
AU  - Schneider-Thoma,
AU  - J.
AU  - Wang,
AU  - D.
AU  - Dong,
AU  - S.
AU  - Samara,
AU  - M.
AU  - Peter,
AU  - N.
AU  - Huhn,
AU  - M.
AU  - Priller,
AU  - J.
AU  - Davis,
AU  - J.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/S2215-0366(22)00304-2
L1  - internal-pdf://3661833531/1-s2.0-S2215036622003042-main.cleaned.pdf
PY  - 2022
SP  - 884-893
T2  - The Lancet. Psychiatry
TI  - The response of subgroups of patients with schizophrenia to different antipsychotic drugs: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36228647
VL  - 9
ER  -
TY  - JOUR
AB  - PURPOSE: To assess the efficacy and safety of selective serotonin reuptake inhibitors (SSRIs) and selective noradrenaline reuptake inhibitors (SNRIs) in comparison with various control contingencies (e.g. pill placebo and cognitive behavioral treatment) for pediatric anxiety disorders. Additionally, we wanted to investigate whether serious adverse events or adverse events are more common with medication treatment compared with pill placebo. 

MATERIALS AND METHODS: Studies were selected if they were randomized controlled trials evaluating SSRIs or SNRIs. Eligible studies included participants aged 17 years or younger. Eleven studies were included, with 2122 participants. Primary outcomes were (1) remission, (2) a continuous scale such as the Social Phobia and Anxiety Inventory for Children and (3) serious adverse events. We also calculated number needed to treat and number needed to harm. 

RESULTS: SSRIs and SNRIs are an effective treatment of childhood anxiety disorders and are superior to pill placebo. While the risk of serious adverse events was low with SSRI/SNRI treatment, there was an increased risk of experiencing behavioral activation with SSRI/SNRI treatment. 

CONCLUSION: SSRI and SNRI treatment is effective for childhood anxiety disorders, with positive effect of treatment outweighing the negative effects.
AN  - 35587815
AU  - Stefansdottir,
AU  - I.
AU  - H.
AU  - Ivarsson,
AU  - T.
AU  - Skarphedinsson,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/08039488.2022.2075460
L1  - internal-pdf://0347028632/Stefansdottir-2022.pdf
PY  - 2022
SP  - 1-10
T2  - Nordic Journal of Psychiatry
TI  - Efficacy and safety of serotonin reuptake inhibitors (SSRI) and serotonin noradrenaline reuptake inhibitors (SNRI) for children and adolescents with anxiety disorders: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35587815
UR  - https://www.tandfonline.com/doi/full/10.1080/08039488.2022.2075460
ER  -
TY  - JOUR
AB  - **Objective:** 
Autism Spectrum Disorder is a neurodevelopmental disorder, with a rapid increase in recognition over the past decade. Interest in alternative therapies is growing annually, such as dietary therapies including gluten-free and/or casein-free diet, and the ketogenic diet. However, there is no consensus on the efficacy and safety of dietary therapy in children with ASD up to now. This study aimed to assess the efficacy and safety of these diet interventions for children with ASD based on a meta-analysis of global data. 

**Method(s):** 
Seven databases (Cochrane Library, PubMed, EMBASE, Web of Science, VIP, CNKI, and Wanfang) were searched according to the established inclusion criteria, from the inception of the databases to August 18, 2021. The Cochrane Bias risk assessment tool was intended to assess the quality of the included studies. Review Manager 5.4 software was used as an efficacy analysis tool of the included studies, taking the core autistic symptoms and scales of ASD as therapeutic efficacy evaluations. 

**Result(s):** 
In total, 7 RCTs with 338 participants were finally obtained. All studies assessed the association between core autistic symptoms and therapeutic diet, showing a statistically significant effect (standard mean difference (SMD) of -0.51, 95% confidence interval (Cl): -0.81 to -0.21), in which two studies which followed the GFD diet reported significant reductions in social behaviors (SMD of-0.41, 95% Cl: -0.75 to -0.06), showing no correlation with the length of the interventions (P &lt; 0.05). Two studies were performed in KD diet suggested a significant effect in core symptoms (SMD of -0.67, 95% Cl: -1.04 to -0.31). No statistically significant changes were observed in the GFCF diet, GFD diet, cognition, communication, and stereotypical behaviors subgroups (all P &gt; 0.05). 

**Conclusion(s):** 
The results of a meta-analysis suggest that diet therapies can significantly ameliorate core symptoms of ASD, and GFD diets are conducive to improving social behaviors. Although the results suggest the effectiveness of dietary therapy for ASD, limited by the small sample size of RCTs, more well-designed, and high-quality clinical trials are needed to validate the above conclusions. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42021277565. Copyright &copy; 2022 Yu, Huang, Chen, Fu, Wang, Pu, Gu and Cai.
AN  - 2015436514
AU  - Yu,
AU  - Y.
AU  - Huang,
AU  - J.
AU  - Chen,
AU  - X.
AU  - Fu,
AU  - J.
AU  - Wang,
AU  - X.
AU  - Pu,
AU  - L.
AU  - Gu,
AU  - C.
AU  - Cai,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fneur.2022.844117
L1  - internal-pdf://2073849497/Efficacy and Safety of Diet Therapies in-2022.pdf
PY  - 2022
T2  - Frontiers in Neurology
TI  - Efficacy and Safety of Diet Therapies in Children With Autism Spectrum Disorder: A Systematic Literature Review and Meta-Analysis
UR  - http://www.frontiersin.org/Neurology
VL  - 13 (no pagination)
ER  -
TY  - JOUR
AB  - Acceptance and Commitment Therapy (ACT) is increasingly used to treat eating disorders (EDs); however, the evidence for ACT with EDs has not been the subject of a systematic review. The current study reviews the evidence of ACT for EDs through January of 2022. PubMed and PsycInfo were searched for treatment studies using three or more ACT processes with adolescents or adults with anorexia nervosa, bulimia nervosa, binge eating disorder and purging disorder spectrum diagnoses. Studies focusing primarily on obesity, weight loss or body image were excluded. Twenty-two intervention studies were identified with a combined total of 674 participants. Five were randomized controlled trials. While the majority of studies focused on anorexia nervosa, these tended to be smaller studies of fewer participants. Results indicated that ACT may show reasonable efficacy for improvements in ED symptoms. However, most studies lacked sufficient methodological rigor and were weak on two or more components of the Effective Public Health Practice Project (EPHPP) Quality Assessment Tool for Quantitative Studies. Future directions and limitations of using the EPHPP for quality assessment of psychological interventions are discussed, as well as strengths and weaknesses of the evidence base in light of the recent ACBS Task Force Report on the Strategies and Tactics of Contextual Behavioral Science Research. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-95999-001
AU  - Onnink,
AU  - C.
AU  - M.
AU  - Konstantinidou,
AU  - Y.
AU  - Moskovich,
AU  - A.
AU  - A.
AU  - Karekla,
AU  - M.
AU  - K.
AU  - Merwin,
AU  - R.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jcbs.2022.08.005
L1  - internal-pdf://2890452399/1-s2.0-S2212144722000709-main.cleaned.pdf
PY  - 2022
SP  - 11-28
T2  - Journal of Contextual Behavioral Science
TI  - Acceptance and Commitment Therapy (ACT) for eating disorders: A systematic review of intervention studies and call to action
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc19&amp;AN=2022-95999-001
UR  - https://www.sciencedirect.com/science/article/pii/S2212144722000709?via%3Dihub
VL  - 26
ER  -
TY  - JOUR
AB  - Since 2006, the U.S. Administration for Children and Families (ACF) has allocated $1.2 billion to a Healthy Marriage and Relationship Education (HMRE) policy initiative that provides grants to community organizations to support relationship education (RE) services for lower income couples and individuals. The policy aim was to help disadvantaged couples and individuals form and sustain healthy, stable relationships and marriages. A significant body of research on the effectiveness of these programs has now accumulated. 

This meta-analytic study reviews all evaluation research reports of adult couple relationship education (CRE) programs supported by the ACF policy initiative to examine their impact on an array of couple, family, and individual well-being outcomes. 

Overall, our review of 32 control-group studies found a range of small but significant effects for couple relationship quality (d = .114), relationship skills (d = .132), mental health (d = .074), and coparenting (d = .033), but non-significant effects for relationship stability, parenting, and child well-being. Supplemental analyses with 19 1-group/pre-post studies showed larger effects. Planned moderator analyses explored significant heterogeneity in most effects, however, revealing interesting implications for practice and research going forward.
AN  - 35040124
AU  - Hawkins,
AU  - A.
AU  - J.
AU  - Hokanson,
AU  - S.
AU  - Loveridge,
AU  - E.
AU  - Milius,
AU  - E.
AU  - Duncan,
AU  - M.
AU  - Booth,
AU  - M.
AU  - Pollard,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/famp.12739
L1  - internal-pdf://3836844536/How effective are ACF-funded couple relat-2022.pdf
PY  - 2022
SP  - 17
T2  - Family Process
TI  - How effective are ACF-funded couple relationship education programs? A meta-analytic study
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35040124
UR  - https://onlinelibrary.wiley.com/doi/10.1111/famp.12739
VL  - 17
ER  -
TY  - JOUR
AB  - Mental illness heightens risk of medical emergencies, emergency hospitalisation, and readmissions. Innovations for integrated medical-psychiatric care within paediatric emergency settings may help adolescents with acute mental disorders to get well quicker and stay well enough to remain out of hospital. We assessed models of integrated acute care for adolescents experiencing medical emergencies related to mental illness (MHR). We conducted a systematic review by searching MEDLINE, PsychINFO, Embase, and Web of Science for quantitative studies within paediatric emergency medicine, internationally. We included populations aged 8-25 years. Our outcomes were length of hospital stay (LOS), emergency hospital admissions, and rehospitalisation. Limits were imposed on dates: 1990 to June 2021. We present a narrative synthesis. This study is registered on PROSPERO: 254,359. 1667 studies were screened, 22 met eligibility, comprising 39,346 patients. Emergency triage innovations reduced admissions between 4 and 16%, including multidisciplinary staffing and training for psychiatric assessment (F(3,42) = 4.6, P &lt; 0.05, N = 682), and telepsychiatry consultations (aOR = 0.41, 95% CI 0.28-0.58; P &lt; 0.001, N = 597). Psychological therapies delivered in emergency departments reduced admissions 8-40%, including psychoeducation (aOR = 0.35, 95% CI 0.17-0.71, P &lt; 0.01, N = 212), risk-reduction counselling for suicide prevention (OR = 2.78, 95% CI 0.55-14.10, N = 348), and telephone follow-up (OR = 0.45, 95% CI 0.33-0.60, P &lt; 0.001, N = 980). Innovations on acute wards reduced readmissions, including guided meal supervision for eating disorders (P = 0.27), therapeutic skills for anxiety disorders, and a dedicated psychiatric crisis unit (22.2 vs 8.5% (P = 0.008). Integrated pathway innovations reduced readmissions between 8 and 37% including family-based therapy (FBT) for eating disorders (X&lt;sup&gt;2&lt;/sup&gt;(1,326) = 8.40, P = 0.004, N = 326), and risk-targeted telephone follow-up or outpatients for all mental disorders (29.5 vs. 5%, P = 0.03, N = 1316). Studies occurred in the USA, Canada, or Australia. Integrated care pathways to psychiatric consultations, psychological therapies, and multidisciplinary follow-up within emergency paediatric services prevented lengthy and repeat hospitalisation for MHR emergencies. Only six of 22 studies adjusted for illness severity and clinical history between before- and after-intervention cohorts and only one reported socio-demographic intervention effects.
AN  - 36151355
AU  - Otis,
AU  - M.
AU  - Barber,
AU  - S.
AU  - Amet,
AU  - M.
AU  - Nicholls,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-022-02085-5
L1  - internal-pdf://3277705498/Otis-2022-Models of integrated care for young.pdf
PY  - 2022
SP  - 24
T2  - European Child &amp; Adolescent Psychiatry
TI  - Models of integrated care for young people experiencing medical emergencies related to mental illness: a realist systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36151355
UR  - https://link.springer.com/content/pdf/10.1007/s00787-022-02085-5.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - Nutrition is fundamental for brain development, but relatively little is known about water-soluble vitamin (WSV) levels and the effect of supplementation on psychiatry symptoms in children and adolescents (CAD) with psychiatric disorders. 

Our team systematically reviewed all studies concerning WSV abnormalities or supplementation in CAD with any psychiatric disorder. We searched for original studies published between 1990 and 15/05/2020 which were not based on retrospective chart review and which included WSV blood level measurements or investigated the effect of WSV supplementation on psychiatric symptoms in psychiatric patients aged 18 or under. 

Forty-two articles were included, 69% of which (N = 29) examined Autism Spectrum Disorders (ASD), with most of these assessing folate or vitamin B&lt;sub&gt;12&lt;/sub&gt; supplementation (N = 22, 75.9% of ASD studies). Meta-analyses showed significantly lower vitamin B&lt;sub&gt;12&lt;/sub&gt; levels in ASD and ADHD patients vs. healthy controls (HC), while folate levels were higher in ADHD patients vs. HC. 

Most of the studies (9/10, 90%) showed a decrease in symptoms as measured by clinical scales after supplementation. There was significant heterogeneity between the studies, however many found different types of vitamin abnormalities in CAD with psychiatric disorders.
AN  - 35034564
AU  - Prades,
AU  - N.
AU  - Varela,
AU  - E.
AU  - Flamarique,
AU  - I.
AU  - Deulofeu,
AU  - R.
AU  - Baeza,
AU  - I.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/1028415X.2021.2020402
L1  - internal-pdf://0470328658/Water-soluble vitamin insufficiency, defi-2022.pdf
PY  - 2022
SP  - 1-23
T2  - Nutritional Neuroscience
TI  - Water-soluble vitamin insufficiency, deficiency and supplementation in children and adolescents with a psychiatric disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35034564
UR  - https://www.tandfonline.com/doi/full/10.1080/1028415X.2021.2020402
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Engagement in multiple substance use risk behaviours such as tobacco smoking, alcohol and drug use during adolescence can result in adverse health and social outcomes. The impact of interventions that address multiple substance use risk behaviours, and the differential impact of universal versus targeted approaches, is unclear given findings from systematic reviews have been mixed. Our objective was to assess effects of interventions targeting multiple substance use behaviours in adolescents. 

**METHODS**
Eight databases were searched to October 2019. Individual and cluster randomised controlled trials were included if they addressed two or more substance use behaviours in individuals aged 8-25 years. Data were pooled in random-effects meta-analyses, reported by intervention and setting. Quality of evidence was assessed using GRADE. Heterogeneity was assessed using between-study variance, tau2 and Iota&lt;sup&gt;2&lt;/sup&gt;, and the p-value of between-study heterogeneity statistic Q. Sensitivity analyses were undertaken using the highest and lowest intra-cluster correlation coefficient (ICC). 

**RESULTS**
 Of 66 included studies, most were universal (n=52) and school-based (n=41). We found moderate quality evidence that universal school-based interventions are likely to have little or no short-term benefit (up to 12 months) in relation to alcohol use (OR 0.94, 95% CI: 0.84, 1.04), tobacco use (OR 0.98, 95% CI: 0.83, 1.15), cannabis use (OR 1.06, 95% CI: 0.86, 1.31) and other illicit drug use (OR 1.09, 95% CI: 0.85, 1.39). For targeted school-level interventions, there was low quality evidence of no or a small short-term benefit: alcohol use (OR 0.90, 95% CI: 0.74-1.09), tobacco use (OR 0.86, 95% CI: 0.66, 1.11), cannabis use (OR 0.84, 95% CI: 0.66-1.07) and other illicit drug use (OR 0.79, 95% CI 0.62-1.02). There were too few family-level (n=4), individual-level (n=2) and combination level (n=5) studies to draw confident conclusions. Sensitivity analyses of ICC did not change results. 

**CONCLUSIONS**
There is low to moderate quality evidence that universal and targeted school-level interventions have no or a small beneficial effect for preventing substance use multiple risk behaviours in adolescents. Higher quality trials and study reporting would allow better evidence syntheses, which is needed given small benefit of universal interventions can have high public health benefit. TRIAL REGISTRATION: Cochrane Database of Systematic Reviews 2014, Issue 11. Art. No.: CD011374. DOI: 10.1002/14651858.CD011374.
AN  - 35658920
AU  - Tinner,
AU  - L.
AU  - Palmer,
AU  - J.
AU  - C.
AU  - Lloyd,
AU  - E.
AU  - C.
AU  - Caldwell,
AU  - D.
AU  - M.
AU  - MacArthur,
AU  - G.
AU  - J.
AU  - Dias,
AU  - K.
AU  - Langford,
AU  - R.
AU  - Redmore,
AU  - J.
AU  - Wittkop,
AU  - L.
AU  - Watkins,
AU  - S.
AU  - H.
AU  - Hickman,
AU  - M.
AU  - Campbell,
AU  - R.
DB  - Alerts 6_2022.enl
DO  - /10.1186/s12889-022-13072-5
L1  - internal-pdf://4011053331/Tinner-2022-Individual-, family- and school-ba.pdf
PY  - 2022
SP  - 1111
T2  - BMC Public Health
TI  - Individual-, family- and school-based interventions to prevent multiple risk behaviours relating to alcohol, tobacco and drug use in young people aged 8-25 years: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35658920
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165543/pdf/12889_2022_Article_13072.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - BACKGROUND: Effective antibullying interventions may reduce the impact of bullying on young people&#039;s mental health. Nevertheless, little is known about their effectiveness in reducing internalizing symptoms such as anxiety or depression, and what factors may influence intervention effects. The aim of this systematic review, meta-analysis, and metaregression is to assess the effects of school-based antibullying interventions on children&#039;s and adolescent&#039;s internalizing symptoms. The secondary aims are to explore potential moderators, intervention components, and reductions in bullying as mediators of intervention effects on internalizing symptoms. 

METHODS: We searched nine databases: PsycINFO, Web of Science, ERIC, SCOPUS, CINAHL, Medline, Embase, ProQuest, and Cochrane Library, and performed an author search of included studies in English from January 1983 to April 2021. We included studies that evaluated school-based antibullying interventions using controlled designs and reporting on both bullying and internalizing outcomes. Random-effects and metaregression models were used to derive Hedges g values with pooled 95% CIs as estimates of effect size and to test associations between moderator variables and effect size estimates. Path analysis was used to test potential mediation using effect size measures of victimization, perpetration, and internalizing outcomes. Quality and risk of bias were assessed using Cochrane collaboration tools. 

RESULTS: This review included 22 studies with 58,091 participants in the meta-analysis. Antibullying interventions had a very small effect in reducing overall internalizing symptoms (ES, 0.06; 95% CI, 0.0284 to 0.1005), anxiety (ES, 0.08; 95% CI, 0.011 to 0.158), and depression (ES, 0.06; 95% CI, 0.014 to 0.107) at postintervention. The reduction in internalizing symptoms did not vary significantly across geographic location, grade level, program duration, and intensity. The intervention component &#039;working with peers&#039; was associated with a significant reduction, and &#039;using CBT techniques&#039; was associated with a significant increase in internalizing outcomes. Bullying victimization and perpetration did not mediate the relationship between intervention condition and internalizing outcomes. 

CONCLUSIONS: Antibullying interventions have a small impact on reducing internalizing symptoms. Ongoing development of antibullying interventions should address how best to maximize their impact on internalizing symptoms to safeguard young people from the damaging mental health outcomes of bullying.
AN  - 35474211
AU  - Guzman-Holst,
AU  - C.
AU  - Zaneva,
AU  - M.
AU  - Chessell,
AU  - C.
AU  - Creswell,
AU  - C.
AU  - Bowes,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13620
L1  - internal-pdf://2586267559/Research Review_ Do antibullying interven-2022.pdf
PY  - 2022
SP  - 26
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Research Review: Do antibullying interventions reduce internalizing symptoms? A systematic review, meta-analysis, and meta-regression exploring intervention components, moderators, and mechanisms
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35474211
VL  - 26
ER  -
TY  - JOUR
AB  - BACKGROUND: Depression and anxiety are prevalent in youth populations and typically emerge during adolescence. Repetitive negative thinking (RNT) is a putative transdiagnostic mechanism with consistent associations with depression and anxiety. Targeting transdiagnostic processes like RNT for youth depression and anxiety may offer more targeted, personalised and effective treatment. 

METHODS: A meta-analysis was conducted to examine the effect of psychological treatments on RNT, depression and anxiety symptoms in young people with depression or anxiety, and a meta-regression to examine relationships between outcomes. 

RESULTS: Twenty-eight randomised controlled trials examining 17 different psychological interventions were included. Effect sizes were small to moderate across all outcomes (Hedge&#039;s g depression = -0.47, CI -0.77 to -0.17; anxiety = -0.42, CI -0.65 to -0.20; RNT = -0.45, CI -0.67 to -0.23). RNT-focused and non-RNT focused approaches had comparable effects; however, those focusing on modifying the process of RNT had significantly larger effects on RNT than those focusing on modifying negative thought content. Meta-regression revealed a significant relationship between RNT and depression outcomes only across all intervention types and with both depression and anxiety for RNT focused interventions only. 

CONCLUSION: Consistent with findings in adults, this review provides evidence that reducing RNT with psychological treatment is associated with improvements in depression and anxiety in youth. Targeting RNT specifically may not lead to better outcomes compared to general approaches; however, focusing on modifying the process of RNT may be more effective than targeting content. Further research is needed to determine causal pathways.
AN  - 36373473
AU  - Bell,
AU  - I.
AU  - H.
AU  - Marx,
AU  - W.
AU  - Nguyen,
AU  - K.
AU  - Grace,
AU  - S.
AU  - Gleeson,
AU  - J.
AU  - Alvarez-Jimenez,
AU  - M.
DB  - Alerts 6_2022.enl
DO  - /10.1017/S0033291722003373
L1  - internal-pdf://2775367496/Bell-2022-The effect of psychological treatmen.pdf
PY  - 2022
SP  - 1-11
T2  - Psychological Medicine
TI  - The effect of psychological treatment on repetitive negative thinking in youth depression and anxiety: a meta-analysis and meta-regression
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36373473
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/8869A5666A3BE58D4D90256E06288C11/S0033291722003373a.pdf/div-class-title-the-effect-of-psychological-treatment-on-repetitive-negative-thinking-in-youth-depression-and-anxiety-a-meta-analysis-and-meta-regression-div.pdf
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Anorexia in children can cause malnutrition, low immunity, growth retardation, and various secondary infections, resulting in a huge burden on society. In East Asia, Chuna manual therapy has been widely used for the treatment of childhood anorexia. We aimed to comprehensively evaluate the effects of Chuna manual therapy for treating childhood anorexia. 

**METHODS**
Twelve databases were comprehensively searched from their inception to September 13, 2022. Only randomized controlled trials assessing Chuna manual therapy for the treatment of childhood anorexia were included. The methodological quality of the included studies was assessed using the Cochrane risk-of-bias tool. The quality of evidence for each main outcome was evaluated using the grading of recommendations assessment, development, and evaluation approach. A meta-analysis was performed, and the pooled data were presented as risk ratios (RRs) with 95% confidence intervals (CIs) for dichotomous outcomes.

**RESULTS**
Twenty-five RCTs involving 2230 participants were included. The meta-analysis showed that Chuna manual therapy had a higher total effective rate (TER) based on anorexia symptoms than that of lysine inositol and vitamin B12 (RR: 1.53, 95% CI: 1.28-1.84), multi-enzyme and multi-vitamin (RR: 1.21, 95% CI: 1.11-1.33), and zinc calcium gluconate (RR: 1.22, 95% CI: 1.06-1.39). There was no significant difference in total effective rate between Chuna manual therapy and zinc gluconate plus lysine. No adverse events associated with Chuna manual therapy were reported. Overall, the included studies had an unclear risk of bias, and the quality of evidence was generally moderate to low.

**CONCLUSION**
Current evidence showed that Chuna manual therapy may be effective and safe for improving anorexia symptoms, especially compared with lysine inositol and vitamin B12, multi-enzyme plus multi-vitamin, and zinc calcium gluconate. However, owing to the low methodological quality of the included studies, more rigorous, high-quality RCTs are required on this topic.
AD  - Lee, Hesol. Clinical Research Coordinating Team, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.Lee, Boram. KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, Republic of Korea.Lee, Sun Haeng. Department of Korean Pediatrics, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.Chang, Gyu Tae. Department of Korean Pediatrics, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
AN  - 36550806
AU  - Lee,
AU  - H.
AU  - Lee,
AU  - B.
AU  - Lee,
AU  - S.
AU  - H.
AU  - Chang,
AU  - G.
AU  - T.
DA  - Dec 16
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1097/MD.0000000000031746
DP  - Ovid Technologies
J2  - Medicine (Baltimore)
KW  - Humans
KW  - Child
KW  - Anorexia/et [Etiology]
KW  - Anorexia/th [Therapy]
KW  - *Anorexia
KW  - Calcium Gluconate
KW  - Lysine
KW  - *Musculoskeletal Manipulations
KW  - Vitamins
KW  - Vitamin B 12
KW  - SQE6VB453K (Calcium Gluconate)
KW  - K3Z4F929H6 (Lysine)
KW  - 0 (Vitamins)
KW  - P6YC3EG204 (Vitamin B 12)
L1  - internal-pdf://3240973337/Chuna manual therapy for the treatment of anor.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Lee, HesolLee, BoramLee, Sun HaengChang, Gyu Tae
PY  - 2022
SP  - e31746
T2  - Medicine
TI  - Chuna manual therapy for the treatment of anorexia in children: A PRISMA-compliant systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36550806
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36550806&amp;id=doi:10.1097%2FMD.0000000000031746&amp;issn=0025-7974&amp;isbn=&amp;volume=101&amp;issue=50&amp;spage=e31746&amp;pages=e31746&amp;date=2022&amp;title=Medicine&amp;atitle=Chuna+manual+therapy+for+the+treatment+of+anorexia+in+children%3A+A+PRISMA-compliant+systematic+review+and+meta-analysis.&amp;aulast=Lee&amp;pid=%3Cauthor%3ELee+H%3C%2Fauthor%3E%3CAN%3E36550806%3C%2FAN%3E%3CDT%3EMeta-Analysis%3C%2FDT%3E
VL  - 101
ER  -
TY  - JOUR
AB  - **Objectives:** 
Mindfulness-based interventions have been receiving more attention in research for children with attention deficit hyperactivity disorder (ADHD). This systematic review and meta-analysis was conducted to synthesize the findings of randomized controlled trials of mindfulness-based interventions for children with ADHD. 

**Methods:** 
A systematic review and meta-analysis of studies published in PsycINFO, PubMed, and Google Scholar was completed from the earliest available date until August 2022. (3) 

**Results:** 
The systematic review included 12 studies that met the inclusion criteria, and the meta-analysis included 11 studies. The overall effect sizes were g = 0.77 for ADHD symptoms, g = 0.03 for externalizing behavior problem, g = 0.13 for internalizing behavior problem, g = 0.43 for mindfulness, and g = 0.40 for parental stress for children with ADHD.

**Conclusion:** 
The results of this systematic review highlight the possible benefits of mindfulness-based interventions for children with ADHD.
AN  - 36429915
AU  - Lee,
AU  - Y.
AU  - C.
AU  - Chen,
AU  - C.
AU  - R.
AU  - Lin,
AU  - K.
AU  - C.
DB  - Alerts 6_2022.enl
DO  - /10.3390/ijerph192215198
L1  - internal-pdf://3297037509/Lee-2022-Effects of Mindfulness-Based Interven.pdf
PY  - 2022
SP  - 17
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Effects of Mindfulness-Based Interventions in Children and Adolescents with ADHD: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36429915
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-19-15198/article_deploy/ijerph-19-15198.pdf?version=1668691938
VL  - 19
ER  -
TY  - JOUR
AB  - BACKGROUND AND OBJECTIVES: 
Guided and unguided self-help prevention and treatment interventions for eating disorders delivered via traditional book format or internet delivery have been widely researched, but no reviews have focused specifically on young people. The aim of this systematic review and meta-analysis was to examine the efficacy of randomised controlled trials of self-help interventions for eating disorders in young people with a mean age between 13 and 24 years. 

METHODS: 
A total of 8 intervention groups across 7 publications of self-help interventions which were prevention and treatment trials for eating disorders, were identified (N = 985 participants; mean pooled age = ~19 years). 

RESULTS: 
There was a significant very small effect (pooled g = -0.17) of self-help interventions at post-treatment which was non-significant at follow-up (pooled g = -0.14). No evidence of publication bias was found. LIMITATIONS: There were limitations of the review, including a lack of active treatment comparisons, a small number of trials included, and few studies included an age range. 

CONCLUSIONS: 
Results from this preliminary meta-analysis suggest very small but significant effects, however further studies are required to determine whether self-help approaches are effective for prevention and treatment of eating disorder symptoms in young people. Future meta-analyses should include a larger number of trials, and younger age range of children to examine the efficacy of self-help interventions for eating disorders in young people.
AN  - 36215935
AU  - O&#039;Mara,
AU  - M.
AU  - Greene,
AU  - D.
AU  - Watson,
AU  - H.
AU  - Shafran,
AU  - R.
AU  - Kenworthy,
AU  - I.
AU  - Cresswell,
AU  - C.
AU  - Egan,
AU  - S.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jbtep.2022.101777
L1  - internal-pdf://3643942609/1-s2.0-S0005791622000556-main.cleaned.pdf
PY  - 2022
SP  - 101777
T2  - Journal of Behavior Therapy &amp; Experimental Psychiatry
TI  - The efficacy of randomised controlled trials of guided and unguided self-help interventions for the prevention and treatment of eating disorders in young people: A systematic review and preliminary meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36215935
VL  - 78
ER  -
TY  - JOUR
AB  - We conducted systematic reviews and meta-analyses to evaluate the efficacy of melatonin versus placebo or other hypnotic agents in improving sleep quality and quantity in patients with chronic insomnia. A literature search on Ovid-MEDLINE, EMBASE, and the Cochrane Library was performed up to November 2020. Sleep onset latency, total sleep time, sleep efficiency, sleep quality and quality of life were examined as outcomes. We identified 24 randomized controlled trials of chronic insomnia including four studies of patients with comorbid insomnia. All studies were compared with placebo. Due to heterogeneity, we conducted subgroup analyses by age group. In non-comorbid insomnia, melatonin was only significantly effective in sleep onset latency and total sleep time in children and adolescents. In adults group, melatonin was not significantly effective in improving sleep onset latency, total sleep time, and sleep efficiency. In comorbid insomnia, melatonin significantly improved sleep onset latency in all age groups, but there was only one study in adults group. In conclusion, melatonin did not appear to be effective in adults but might be effective in children and adolescents with chronic insomnia for both comorbid insomnia and non-comorbid insomnia. Further studies are needed to establish the efficacy and safety of melatonin by age groups.
AN  - 36179487
AU  - Choi,
AU  - K.
AU  - Lee,
AU  - Y.
AU  - J.
AU  - Park,
AU  - S.
AU  - Je,
AU  - N.
AU  - K.
AU  - Suh,
AU  - H.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.smrv.2022.101692
L1  - internal-pdf://2955419877/1-s2.0-S1087079222001058-main.cleaned.pdf
PY  - 2022
SP  - 101692
T2  - Sleep Medicine Reviews
TI  - Efficacy of melatonin for chronic insomnia: Systematic reviews and meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36179487
VL  - 66
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
Because most youth psychotherapies are developed and tested in high-income countries, relatively little is known about their effectiveness or moderators in low- and middle-income countries (LMICs). To address this gap, we conducted a meta-analysis of randomized controlled trials (RCTs) testing psychotherapies for youth with multiple psychiatric conditions in LMICs, and we tested candidate moderators.

**METHOD**
We searched nine international databases for RCTs of youth psychotherapies in LMICs published through January 2021. The RCTs targeted elevated symptoms of youth anxiety (including post-traumatic stress disorder [PTSD] and obsessive compulsive disorder [OCD]), depression, conduct, and attention problems. Using robust variance estimation, we estimated the pooled effect sizes (Hedges g) at post-treatment and follow-up for intervention versus control conditions.

**RESULTS**
Of 5,145 articles identified, 34 (with 43 treatment-control comparisons and N=4176 participants) met methodological standards and were included. The overall pooled g with winsorized outliers was 1.01 (95% CI=0.72 1.29, p&lt;.001) at post-treatment and 0.68 (95% CI=0.29 1.07, p=.003) at follow-up. Interventions delivered by professional clinicians significantly outperformed those delivered by lay-providers (g=1.59 vs. 0.53). Interventions developed non-locally were more effective if not adapted to local contexts than if adapted locally (g=2.31 vs. 0.66), highlighting a need for further research on effective adaptations. Significant risk of bias was identified.

**CONCLUSION**
 Overall pooled effects of youth psychotherapies in LMICs were markedly larger than those in recent comparable non-LMIC meta-analyses, which have shown small-to-medium effects for youth psychotherapies. Findings highlight the potential benefits of youth psychotherapies in LMICs as well as a need for more RCTs and improved study quality.
AD  - Venturo-Conerly, Katherine E. Harvard University, Cambridge Massachusetts. Electronic address: kventuroconerly@g.harvard.edu.Eisenman, Danielle. Harvard University, Cambridge Massachusetts.Wasil, Akash R. University of Pennsylvania, Philadelphia.Singla, Daisy R. Center of Addiction and Mental Health, Toronto, Ontario, Canada; The University of Toronto, Ontario, Canada; and Sinai Health, Toronto, Ontario, Canada.Weisz, John R. Harvard University, Cambridge Massachusetts.
AN  - 36563875
AU  - Venturo-Conerly,
AU  - K.
AU  - E.
AU  - Eisenman,
AU  - D.
AU  - Wasil,
AU  - A.
AU  - R.
AU  - Singla,
AU  - D.
AU  - R.
AU  - Weisz,
AU  - J.
AU  - R.
DA  - Dec 16
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jaac.2022.12.005
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
L1  - internal-pdf://1044011243/1-s2.0-S0890856722019803-main.cleaned.pdf
LA  - English
N1  - Using Smart Source ParsingDecVenturo-Conerly, Katherine EEisenman, DanielleWasil, Akash RSingla, Daisy RWeisz, John RS0890-8567(22)01980-3
PY  - 2022
SP  - 16
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Meta-analysis: The Effectiveness of Youth Psychotherapy Interventions in Low- and Middle-Income Countries
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36563875
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36563875&amp;id=doi:10.1016%2Fj.jaac.2022.12.005&amp;issn=0890-8567&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2022&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Meta-analysis%3A+The+Effectiveness+of+Youth+Psychotherapy+Interventions+in+Low-+and+Middle-Income+Countries.&amp;aulast=Venturo-Conerly&amp;pid=%3Cauthor%3EVenturo-Conerly+KE%3C%2Fauthor%3E%3CAN%3E36563875%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 16
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Mindfulness-based interventions (MBIs) have been applied in school settings for adolescents with symptoms of stress, depression, and anxiety; however, general conclusions of the efficacy of such interventions remain unclear. This meta-analysis reviewed randomized-controlled MBI trials for stress, depression, and anxiety in school settings.

**METHODS**
 One hundred one records were included after removing duplicates. Nine studies met inclusion criteria, totalling 5046 adolescents aged 12-18. Eighteen comparisons between an MBI and a control group were analyzed. 

**RESULTS**
The overall effect for symptoms of the 17 observations including stress, depression, and anxiety resulted in a significant improvement with a small effect size (k = 17, n = 3721, Hedge&#039;s g = .33, CI 95% .17-.49 p &lt; .01). Subgroup analysis revealed that when MBIs were compared to an active control group effects were not significant (k = 5, n = 2753, Hedge&#039;s g = .27, CI 95% -.03-.57 p = .08), and when compared to an inactive control group the effect was significant with a small effect size (k = 5, n = 1065, Hedge&#039;s g = .38, CI 95% .02-.75 p &lt; .05). Analysis of the interventions on a per symptom basis yielded a significant and moderate effect size for perceived stress (k = 7, n = 1116, Hedge&#039;s g = .55, CI 95% .31-.79 p &lt; .01); however, there were no significant effects for depression (k = 6, n = 3172, Hedge&#039;s g = .20, CI 95% -.05-.44 p &lt; .01) and anxiety (k = 4, n = 837, Hedge&#039;s g = .19, CI 95% -.14-.53 p = .25). 

**CONCLUSIONS**
 The impact of MBIs in school settings for adolescents yielded a significant improvement for stress, but did not for depression and anxiety. The effects were significant when compared to inactive controls, but not when compared to active controls. Implications of these findings are discussed.
AN  - 35765773
AU  - Fulambarkar,
AU  - N.
AU  - Seo,
AU  - B.
AU  - Testerman,
AU  - A.
AU  - Rees,
AU  - M.
AU  - Bausback,
AU  - K.
AU  - Bunge,
AU  - E.
DB  - Alerts 6_2022.enl
DO  - /10.1111/camh.12572
L1  - internal-pdf://2642395507/Child Adoles Ment Health - 2022 - Fulambarkar.pdf
PY  - 2022
SP  - 28
T2  - Child &amp; Adolescent Mental Health
TI  - Review: Meta-analysis on mindfulness-based interventions for adolescents&#039; stress, depression, and anxiety in school settings: a cautionary tale
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35765773
VL  - 28
ER  -
TY  - JOUR
AB  - BACKGROUND AND OBJECTIVES: 
Responsive feeding may improve health outcomes in preterm and low birth weight (LBW) infants. Our objective was to assess effects of responsive compared with scheduled feeding in preterm and LBW infants. 

METHODS: 
Data sources include PubMed, Scopus, Web of Science, CINAHL, LILACS, and MEDICUS. Randomized trials were screened. Primary outcomes were mortality, morbidity, growth, neurodevelopment. Secondary outcomes were feed intolerance and duration of hospitalization. Data were extracted and pooled with random-effects models. 

RESULTS: 
Eleven eligible studies were identified, and data from 8 randomized control trials with 455 participants were pooled in the meta-analyses. At discharge, the mean difference in body weight between the intervention (responsive feeding) and comparison (scheduled feeding) was -2.80 g per day (95% CI -3.39 to -2.22, I2 = 0%, low certainty evidence, 4 trials, 213 participants); -0.99 g/kg per day (95% CI -2.45 to 0.46, I2 = 74%, very low certainty evidence, 5 trials, 372 participants); -22.21 g (95% CI -130.63 to 86.21, I2 = 41%, low certainty evidence, 3 trials, 183 participants). The mean difference in duration of hospitalization was -1.42 days (95% CI -5.43 to 2.59, I2 = 88%, very low certainty evidence, 5 trials, 342 participants). There were no trials assessing other growth outcomes (eg, length and head circumference) mortality, morbidity or neurodevelopment. Limitations include a high risk of bias, heterogeneity, and small sample size in included studies. 

CONCLUSIONS: 
Overall, responsive feeding may decrease in-hospital weight gain. Although the evidence is very uncertain, responsive feeding may slightly decrease the duration of hospitalization. Evidence was insufficient to understand the effects of responsive compared with scheduled feeding on mortality, morbidity, linear growth, and neurodevelopmental outcomes in preterm and LBW infants.
AN  - 35921679
AU  - Talej,
AU  - M.
AU  - Smith,
AU  - E.
AU  - R.
AU  - Lauria,
AU  - M.
AU  - E.
AU  - Chitale,
AU  - R.
AU  - Ferguson,
AU  - K.
AU  - He,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1542/peds.2022-057092F
L1  - internal-pdf://3047263179/Talej-2022-Responsive Feeding for Preterm or L.pdf
PY  - 2022
SP  - 01
T2  - Pediatrics
TI  - Responsive Feeding for Preterm or Low Birth Weight Infants: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35921679
UR  - https://watermark.silverchair.com/peds_2022057092f.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAvEwggLtBgkqhkiG9w0BBwagggLeMIIC2gIBADCCAtMGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMGnlhcDQkLZxJ5QKUAgEQgIICpLYbfcV5lLxYjzcMqrQJSugFaKSqT46GgsnhdinS8-f9NNyry2ClmByELc5R5kEeNUtCFWLsPQ2aU62krxj1tA8wiqvNlXhUkHoMK5iF7UIXkyupXtZRMqV0HzgfDrgFohuNq4X3vrqYA8sdJoyDZuKIMdB6W7neO2-NSHdj9z4nCmvALsWrxwHlz7Wqpikv48VZwjbmkQozXGFrm2WqaCMUhYFQNh-0SaJR1_6BQKab5rb3cBBgifrOM0QV4qHc3D3JMnjJLzUdinZ_UOSFPyKK1uq4eoRuFmqgmkFfxZ6xaqubrQNA0B7Wrr5BL0FPh0Lssb1ZUW-c8o6IY5VQQlDkfAohSSvlOwzC2NUZUXDTzOq38avqY7J4c2c5yFsZbWG-w4QQ6OmeryygSRYSoxNK7xWBeKWAOvDGHr2lvNGEtlWg0_YH03WEQmDuLuerfiptc3RBlJES8XtLF_1bZcCEF0J63iO81eRkBl6QYVbTX_5tgOqq9rl5FrDkrZ-_lGJCWo3wbfwuYvWigOi-mXeUXqzoOWkTS_1Ww8Ywh_3mHxR6ebd6_bOgQoG2-iOExvNIkSyngpXaU4tq_Y2pkQTMgav_VAg6WYgFCOqCtMaqatGgJydgm1Vvp06gXY6AEZrw6E7W3avDI6Ov4OBQUZmGDTepQ5221uCMuDykgq8kHPpxpheAoeodalBt7vU0mZiGDw6cMQb8KVgt-okkbB-R0djAfNOhDiiBPjF9jhfQzu6BtZfoyF4n_NxxH40JEwAlYIR5rcXyouTq7zIpgwfDZzODGeQM3lc0fLsCD-aW3tOIs5YrawfXZwkQGIIaBuvsQsNEJ2jN5hIDP65ZKlIvE61Gg7Ye9kThuVYRdijr6FT7j0EQaLhTq4kPtKirMyyLLyw
VL  - 150
ER  -
TY  - JOUR
AB  - As of 2016, the Centers for Disease Control and Prevention states that approximately 9.4% (6.1 million) of children 2-17 yr of age have been diagnosed with attention deficit hyperactivity disorder (ADHD). Recent studies have looked at physical activity (PA) as a possible alternative and/or adjunct treatment option for children with ADHD. There is no clear picture on the amount of PA needed to elicit an improvement or what type of exercise is most beneficial. 

The Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines were used to search six databases to identify studies that assessed the relationship between PA and executive functioning (EF) in children with ADHD. Cochrane&#039;s Risk of Bias tool was used, and dose response using MET levels was attempted. Eligibility criteria included (a) peer-reviewed, experimental, quantitative study designs that included a control group or a within-subject design; (b) published in English between January 1997 and December 31, 2019; (c) children 5-18 yr of age; and (d) assessed the relationship between PA and EF in children with ADHD. 

A total of 49 full-text manuscripts were identified, with 24 studies being included in the final review. Although results should be interpreted with caution because of variability across studies and a high risk of bias, there seems to be consensus that acute and training PA positively influence inhibition and cognitive flexibility. More rigorous study protocols that clearly identify which EF component they are assessing and how they are addressing areas of bias will provide a more cohesive representation of the evidence on how to effectively incorporate PA to enhance EF in children with ADHD. Dose response using MET levels is also needed to improve our knowledge of how much exercise is needed to affect EF in this population.
AN  - WOS:000728800200001
AU  - Barudin-Carreiro,
AU  - A.
AU  - M.
AU  - Camhi,
AU  - S.
AU  - M.
AU  - Lindsay,
AU  - A.
AU  - C.
AU  - Wright,
AU  - J.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1249/tjx.0000000000000183
L1  - internal-pdf://2538605674/01933607-202201140-00003.cleaned.pdf
PY  - 2022
SP  - 16
T2  - Translational Journal of the American College of Sports Medicine
TI  - Physical Activity and Executive Function in Children with ADHD: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000728800200001
VL  - 7
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
Recent research has investigated the use of serious games as a form of therapeutic intervention for depression and anxiety in young people. *

**AIMS** To conduct a systematic review and meta-analysis into the effectiveness of gaming interventions for treating either depression or anxiety in individuals aged 12-25 years. 

**METHOD**
An electronic search was conducted on the 30 March 2020, using PsycINFO, ISI Web of Science Core Collection, Medline and EMBASE databases. Standardised effect sizes (Hedge&#039;s g) were calculated for between-participant comparisons between experimental (therapeutic intervention) and control conditions, and within-participant comparisons between pre- and post-intervention time points for repeated measures designs. 

**RESULTS**
Twelve studies (seven randomised controlled trials (RCTs) and five non-randomised studies) were included. For RCTs, there was a statistically significant and robust effect (g = -0.54, 95% CI -1.00 to -0.08) favouring the therapeutic intervention when treating youth depression. For non-RCTs, using a repeated measures design, the overall effect was also strong (g = -0.75, 95% CI -1.64 to 0.14) favouring therapeutic intervention, but this was not statistically significant. Interestingly, we found no statistically significant effect for treating youth anxiety. 

**CONCLUSIONS**
There is preliminary evidence to suggest that gaming interventions are an effective treatment for youth depression, but not anxiety. Further research is warranted to establish the utility, acceptability and effectiveness of gaming interventions in treating mental health problems in young people.
AN  - 34991767
AU  - Townsend,
AU  - C.
AU  - Humpston,
AU  - C.
AU  - Rogers,
AU  - J.
AU  - Goodyear,
AU  - V.
AU  - Lavis,
AU  - A.
AU  - Michail,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/bjo.2021.1078
L1  - internal-pdf://4192839869/The effectiveness of gaming interventions-2022.pdf
PY  - 2022
SP  - e25
T2  - BJPsych Open
TI  - The effectiveness of gaming interventions for depression and anxiety in young people: systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34991767
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/7206B6C2FCB40355582267D37A9B7231/S2056472421010784a.pdf/div-class-title-the-effectiveness-of-gaming-interventions-for-depression-and-anxiety-in-young-people-systematic-review-and-meta-analysis-div.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **Background** 
There has been an increase in the number of orphans around the world as a result of natural or man-made causes. Orphans are likely to face a number of challenges throughout their lives that go unrecognized. Considering these challenges, much focus needs to be given to manage their mental health issues. 

**Purpose** 
The aim of the study is to examine the effectiveness of various psychosocial interventions in managing post-traumatic stress symptoms, emotional and behavioural problems, and depression among orphans. 

**Method** 
Electronic searches on seven databases was done to identify studies investigating the effectiveness of interventions among orphans. The effectiveness of psychosocial interventions to reduce post-traumatic stress symptoms, emotional and behavioural problems, and depression was analyzed in seventeen studies. The risk of bias was assessed using the Cochrane risk of bias tool. 

**Result** 
The overall intervention effect size of post-traumatic stress symptoms was found to be high with high heterogeneity, while low effect size for emotional and behavioural problems, and depression with substantial heterogeneity. Publication bias and exploratory moderating effects of study design and intervention type were also analyzed. 

**Conclusion** 
Psychosocial interventions were more effective in reducing post-traumatic stress symptoms when compared to emotional and behavioural problems and depression.
AN  - WOS:000890318200001
AU  - Darsana,
AU  - Kumar,
AU  - S.
AU  - V.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1177/00332941221141309
L1  - internal-pdf://0215182016/00332941221141309.cleaned.pdf
PY  - 2022
SP  - 22
T2  - Psychological Reports
TI  - Psychosocial Intervention Among Orphans: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000890318200001
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Positive emotions help children and adolescents develop good personalities and interpersonal relationships. Evidence shows that participation in physical activity is associated with positive emotions in young people. However, there is still a lack of studies on the effects of physical activity on positive emotions in children and adolescents. 

OBJECTIVE:
The purpose of this systematic review and meta-analysis was to examine the effects of physical activity on positive emotions in children and adolescents. 

METHODS: 
Online databases (Scopus, PubMed, Web of Science, EBSCOhost, and APA PsycInfo) were searched from inception to August 2022. RESULT: A total of 24 articles were eventually included representing 3907 participants from 14 different countries. Overall, the effect of physical activity interventions on positive emotions was significant. The studies revealed that positive emotions were statistically better in the physical activity participation group than in the control group without physical activity (SMD = 0.62, 95% CI: (0.24, 1.01), (p &lt; 0.01). Based on subgroup analyses, we found that participation in aerobic exercise for 30-60 min in adolescents aged &gt;=12 years had a more significant intervention effect on positive emotions. 

CONCLUSION: 
These findings indicate that the moods of children and adolescents who participate in physical activity significantly improved compared with the moods of those who do not participate in physical activity. The age, exercise type, and exercise duration of adolescents are important factors influencing the positive emotions resulting from physical activity interventions.
AN  - 36361067
AU  - Li,
AU  - J.
AU  - Huang,
AU  - Z.
AU  - Si,
AU  - W.
AU  - Shao,
AU  - T.
DB  - Alerts 6_2022.enl
DO  - /10.3390/ijerph192114185
L1  - internal-pdf://3405893118/Li-2022-The Effects of Physical Activity on Po.pdf
PY  - 2022
SP  - 30
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - The Effects of Physical Activity on Positive Emotions in Children and Adolescents: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36361067
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-19-14185/article_deploy/ijerph-19-14185-v2.pdf?version=1667201217
VL  - 19
ER  -
TY  - JOUR
AB  - Teen Psychological Dating Violence (TPDV) is a serious public health concern. However, there is limited evidence on the capacity of programs to prevent this form of violence. This study aimed to conduct a systematic review and meta-analysis of RCTs to evaluate the efficacy of prevention programs for TPDV. PsycINFO/Eric/PsycArticles, PubMed and Web of Science were searched from inception through January 2021 to identify RCTs of prevention programs for adolescents that reported a measure of TPDV. The effect sizes were computed as the difference between the prevention program and control group at post or follow-up assessment by calculating Hedges&#039;s g with a random-effect model. Thirteen trials met inclusion criteria and were included in the meta-analysis. There was a small but significant effect size in favor of the prevention group as compared to the control condition for victimization (g=0.23; 95% CI, 0.10 to 0.37; p&lt;.001) and perpetration (g=0.24; 95% CI, 0.12 to 0.37; p&lt;.001) of TPDV. Overall, the combined effect size for any TPDV perpetration/victimization was 0.22 (95% CI, 0.11 to 0.34; p&lt;.001). Exploratory subgroup analysis showed that programs implemented at multiple levels (such as home, school, community) reported significantly larger effect sizes compared to single-level interventions. Significant differences in effect sizes were also associated with the type of scale used to assess TPDV. Current evidence suggests that intervention programs for TPDV may be effective, particularly when implemented at multiple levels. Further research focusing on refining tools to assess TPDV is needed.
AN  - 35469775
AU  - Piolanti,
AU  - A.
AU  - Foran,
AU  - H.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ypmed.2022.107053
L1  - internal-pdf://2957794471/Psychological violence in dating relation-2022.pdf
PY  - 2022
SP  - 107053
T2  - Preventive Medicine
TI  - Psychological violence in dating relationships among adolescents: A systematic review and meta-analysis of prevention programs
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35469775
UR  - https://www.sciencedirect.com/science/article/pii/S0091743522001013?via%3Dihub
ER  -
TY  - JOUR
AB  - **Background**
Adolescent depression and anxiety are among the leading contributors to health burden worldwide. &#039;Relaxation Techniques (RTs)&#039; are a &quot;set of strategies to improve physiological response to stress&quot; and are frequently cited as an active ingredient of trans-diagnostic, psychosocial interventions for scaling-up care for preventing and treating these conditions in adolescents. However, there is a little evidence on the effectiveness of &#039;relaxation techniques&#039; for this age group. 

**Aim(s)**
As a part of the Wellcome Trust&#039;s Active Ingredients commission, we did a systematic review and meta-analysis to evaluate the effectiveness of RTs to reduce the symptoms of distress, anxiety and depression in young people, aged 14 to 24 years old, globally. 

**Method(s)**
We searched 10 academic databases to include 65 Randomized Controlled Trials (RCTs) of relaxation-based interventions for young people with the symptoms of anxiety and depression. Primary outcomes were reduction in symptoms of distress, anxiety and/or depression. We employed the Cochrane risk of bias tool and GRADE (Grading of Recommendations, Assessment, Development and Evaluations) guidelines to assess certainty of outcomes pertaining to anxiety, depression and distress. Standardized mean difference was estimated using effect size. 

**Result(s)**
The analysis of 65 RCTs with 8009 young people showed that RTs were highly effective in treating anxiety (pooled effect size of (Standardized Mean Difference-SMD) - 0.54 (95% CI - 0.69 to - 0.40); moderately effective in reducing distress (SMD = - 0.48, 95% CI - 0.71 to - 0.24) and had only a weak effect on improving depression in young people (SMD = - 0.28 (95% CI - 0.40% to - 0.15). Face-to-face delivered relaxation techniques yielded higher effect size (SMD = - 0.47, 95% CI - 0.64 to - 0.30) compared to online delivery (SMD = - 0.22, 95% CI - 0.48 to 0.04) for anxiety. 

**Conclusion(s)**
Most of the included studies were from High Income Countries (HICs) and had a high risk of bias. Further high-quality studies with low risk of bias, especially from low resource settings are needed to evaluate the evidence for effectiveness of RTs as an active ingredient of psychological interventions to reduce the symptoms of distress, anxiety and depression in young people. Copyright &copy; 2022, The Author(s).
AN  - 2018048748
AU  - Hamdani,
AU  - S.
AU  - U.
AU  - Zill
AU  - e,
AU  - H.
AU  - Zafar,
AU  - S.
AU  - W.
AU  - Suleman,
AU  - N.
AU  - Um
AU  - ul,
AU  - B.
AU  - Waqas,
AU  - A.
AU  - Rahman,
AU  - A.
DB  - Alerts 6_2022.enl
DO  - /10.1186/s13033-022-00541-y
L1  - internal-pdf://0014009331/Hamdani-2022-Effectiveness of relaxation techn.pdf
PY  - 2022
T2  - International Journal of Mental Health Systems
TI  - Effectiveness of relaxation techniques &#039;as an active ingredient of psychological interventions&#039; to reduce distress, anxiety and depression in adolescents: a systematic review and meta-analysis
UR  - http://www.ijmhs.com/
UR  - https://ijmhs.biomedcentral.com/track/pdf/10.1186/s13033-022-00541-y.pdf
VL  - 16(1) (no pagination)
ER  -
TY  - JOUR
AB  - **Background:** 
People with autism spectrum disorder (ASD) have difficulties recognizing emotions. Studies showed that virtual reality (VR) and computerized training programs might be used as potential tools for enhancing emotion recognition in such people. However, some inconsistencies were observed between the studies. 

**Objective:** 
In the current systematic review and meta-analysis, the potential of computerized and VR training programs were evaluated for enhancing emotion recognition in people with ASD. 

**Method:** 
Using PRISMA guidelines and a PICO model, eligible studies were retrieved and the pooled effect size was calculated. Results: This meta-analysis obtained the pooled effect of Cohen&#039;s d = 0.69 (95% CI: [0.49, 0.89]) that showed the positive effect of VR and computerized training on emotion recognition in people with ASD. The effectiveness was confirmed for different types of study design, and for both children and adults, while it was larger for non-VR computerized programs compared with VR counterparts. 

**Conclusion**
Due to the small sample size of this study and the substantial heterogeneity between studies, the outcomes should be considered with caution in practice. However, these outcomes can be considered for optimizing suitable computerized applications or as the hypothesis for future studies. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-56345-001
AU  - Farashi,
AU  - S.
AU  - Bashirian,
AU  - S.
AU  - Jenabi,
AU  - E.
AU  - Razjooyan,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/20473869.2022.2063656
L1  - internal-pdf://2102677165/Effectiveness of virtual reality and comp-2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - International Journal of Developmental Disabilities
TI  - Effectiveness of virtual reality and computerized training programs for enhancing emotion recognition in people with autism spectrum disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-56345-001
UR  - https://www.tandfonline.com/doi/full/10.1080/20473869.2022.2063656
ER  -
TY  - JOUR
AB  - **Background**
Challenging classroom behaviors can interfere with student social and academic functioning and may be harmful to everyone in schools. Self-management interventions within schools can address these concerns by helping students develop necessary social, emotional, and behavioral skills. Thus, the current systematic review synthesized and analyzed school-based self-management interventions used to address challenging classroom behaviors.

**Objectives**
The current study aimed to inform practice and policy by (a) evaluating the effectiveness of self-management interventions at improving classroom behaviors and academic outcomes and (b) examining the state of research for self-management interventions based on existing literature.

**Search Methods**
Comprehensive search procedures included electronically searching online databases (e.g., EBSCO Academic Search Premier, MEDLINE, ERIC, PsycINFO), hand-searching 19 relevant journals (e.g., School Mental Health, Journal of School Psychology), reference-list searching 21 relevant reviews, and searching gray literature (e.g., contacting authors, searching online dissertation/theses databases and national government clearinghouses/websites). Searches were completed through December of 2020.

**Selection Criteria**
Included studies employed either a multiple group-design (i.e., experimental or quasi-experimental) or single-case experimental research design and met the following criteria: (a) utilized a self-management intervention, (b) conducted in a school setting, (c) included school-aged students, and (d) assessed classroom behaviors.

**Data Collection and Analysis**
Standard data collection procedures expected by the Campbell Collaboration were used in the current study. Analyses for single-case design studies incorporated three-level hierarchical models to synthesize main effects, and meta-regression for moderation. Further, robust variance estimation was applied to both single-case design and group-design studies to account for dependency issues.

**Main Results**
Our final single-case design sample included 75 studies, 236 participants, and 456 effects (i.e., 351 behavioral outcomes and 105 academic outcomes). Our final group-design sample included 4 studies, 422 participants, and 11 total behavioral effects. Most studies occurred in the United States, in urban communities, in public schools, and in elementary settings. Single-case design results indicated that self-management interventions significantly and positively impacted both student classroom behaviors (LRRi&thinsp;=&thinsp;0.69, 95% confidence interval [CI] [0.59, 0.78]) and academic outcomes (LRRi&thinsp;=&thinsp;0.58, 95% CI [0.41, 0.76]). Single-case results were found to be moderated by student race and special education status, whereas intervention effects were more pronounced for African American students (F&thinsp;=&thinsp;5.56, p&thinsp;=&thinsp;0.02) and students receiving special education services (F&thinsp;=&thinsp;6.87, p&thinsp;=&thinsp;0.01). Single-case results were not found to be moderated by intervention characteristics (i.e., intervention duration, fidelity assessment, fidelity method, or training). Despite positive findings for single-case design studies, risk of bias assessment indicated methodological shortcomings that should be considered when interpreting findings. A significant main effect of self-management interventions for improving classroom behaviors was also revealed for group-design studies (g&thinsp;=&thinsp;0.63, 95% CI [0.08, 1.17]). However, these results should be interpreted with caution given the small number of included group-design studies.

**Implications for Policy, Practice, and Research**
The current study, conducted using comprehensive search/screening procedures and advanced meta-analytic techniques, adds to the large amount of evidence indicating that self-management interventions can be successfully used to address student behaviors and academic outcomes. In particular, the use specific self-management elements (i.e., self-determining a performance goal, self-observing and recording progress, reflecting on a target behavior, and administering primary reinforcers) should be considered within current interventions as well as in the development of future interventions. Future research should aim to assess the implementation and effects of self-management at the group or classroom-level within randomized controlled trials.
AU  - Smith,
AU  - T.
AU  - Thompson,
AU  - A.
AU  - Maynard,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/cl2.1223
L1  - internal-pdf://2738211694/Campbell Systematic Reviews - 2022 - Smith - S.pdf
PY  - 2022
T2  - Campbell Systematic Reviews
TI  - Self-management interventions for reducing challenging behaviors among school-age students: A systematic review
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Levels of well-being are declining, whereas rates of mental health problems remain high in young people. The World Health Organization defines mental health as not merely the absence of mental disorder but also includes social and psychological well-being as integral to positive mental health, highlighting that mental health is applicable to young people with mental health conditions and those without a diagnosis of a mental health condition. Reduced mental well-being have been identified in studies of young people with clinical populations, as well as in populations consisting of nonclinical young people. Self-help digital interventions can be delivered at mass at a low cost and without the need for trained input, thereby facilitating access to support for well-being. Self-help interventions are effective in young people with mental health conditions, but systematic reviews of such studies have been limited to randomized controlled trials, have not included reduced well-being as an inclusion criterion, and do not consider engagement factors such as retention. 

OBJECTIVE: 
The objective of this study was to systematically review all controlled studies of digitally delivered, self-administered interventions for young people aged 9 to 25 years, with perceived or clinically diagnosed reduced psychological well-being. Participant retention and effectiveness of the interventions were also explored. 

METHODS: 
A systematic search of the PsycInfo, EMBASE, Cochrane, Scopus, and MEDLINE databases from inception to 2021, reference searches of relevant papers, and gray literature was carried out for digitally controlled studies conducted with young people with perceived or clinically diagnosed reduced well-being, aimed at improving psychological well-being. Data were extracted to identify the effectiveness and retention rates of the interventions and the quality of the studies. 

RESULTS: 
Overall, 1.04% (12/1153) of studies met the inclusion criteria: 83% (10/12) of studies were randomized controlled trials and 17% (2/12) were controlled pre-post studies. Most (6/12, 50%) studies aimed to improve symptoms of depression; 3 interventions aimed at both anxiety and depressive symptoms and 2 studies aimed at improving social functioning difficulties. Owing to the high risk of bias across interventions and lack of similar outcome measures, a meta-analysis was not conducted. Retention rates across studies were regarded as good, with moderate to high retention. Overall, the findings indicated that predominantly self-administered self-help interventions improved well-being in the areas targeted by the intervention and identified additional areas of well-being that were positively affected by interventions. Few interventions supported psychological well-being that was different from those used by young people with a clinical diagnosis of mental illness or young people from neurodiverse backgrounds. 

CONCLUSIONS: 
The findings, along with the advantages of self-help interventions, highlight the need for upscaling self-help interventions to better support vulnerable populations of young people who experience poor psychological well-being. TRIAL REGISTRATION: PROSPERO CRD42019129321; https://tinyurl.com/4fb2t4fz.
AN  - 36018675
AU  - Babbage,
AU  - C.
AU  - M.
AU  - Jackson,
AU  - G.
AU  - M.
AU  - Davies,
AU  - E.
AU  - B.
AU  - Nixon,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/25716
L1  - internal-pdf://2358343840/pdf.cleaned (16).pdf
PY  - 2022
SP  - e25716
T2  - JMIR Mental Health
TI  - Self-help Digital Interventions Targeted at Improving Psychological Well-being in Young People With Perceived or Clinically Diagnosed Reduced Well-being: Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36018675
VL  - 9
ER  -
TY  - JOUR
AB  - PURPOSE: 
To explore the effects of physical exercise intervention on the cardinal symptoms, motor skills and executive function among children with attention deficit hyperactivity disorder (ADHD). 

METHODS: 
Literature searches for randomized controlled trials (RCTs) were performed in PubMed, The Cochrane Library, Web of Science, Embase, CNKI, CBM, VIP and Wanfang databases from the time of database construction to March 28, 2021. Screening was conducted based on inclusion and exclusion criteria. The Cochrane bias risk assessment tools were used to evaluate methodological quality. Relevant data were analyzed with RevMan5.3.5 software, and Stata16.0 was used for publication bias tests. 

RESULTS: 
A total of 15 RCTs with 734 subjects were included. The meta-analysis showed that physical exercise can improve the attention of ADHD children (standardized mean difference [SMD] = -0.60, 95% confidence interval [CI] [-1.10, -0.11], p &lt; 0.01), executive function (SMD = 1.22, 95% CI [0.61, 1.82], p &lt; 0.01), and motor skills (SMD = 0.67, 95% CI [0.22, 1.12], p &lt; 0.01). There were no significant effects on hyperactivity (SMD = 0.06, 95% CI [-0.26, 0.37], p = 0.72), depression (SMD = -0.72, 95% CI [-1.55, 0.11], p = 0.09), social problems (SMD = -0.27, 95% CI [-0.64, 0.09], p = 0.14), or aggressive behavior (SMD=-0.24, 95% CI [-0.69, -0.21], p = 0.30). Intervention duration and frequency might be the source of heterogeneity. 

CONCLUSION: 
Physical exercise can help alleviate the symptoms of ADHD in children. Specifically, it can improve attention, executive function, and motor skills.
AN  - 35305344
AU  - Sun,
AU  - W.
AU  - Yu,
AU  - M.
AU  - Zhou,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.psychres.2022.114509
L1  - internal-pdf://4028929477/Effects of physical exercise on attention-2022.pdf
PY  - 2022
SP  - 114509
T2  - Psychiatry Research
TI  - Effects of physical exercise on attention deficit and other major symptoms in children with ADHD: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35305344
UR  - https://www.sciencedirect.com/science/article/pii/S0165178122001238?via%3Dihub
VL  - 311
ER  -
TY  - JOUR
AB  - ASD is a neurodevelopmental disorder that is primarily treated with psychosocial intervention. However, it is costly and requires extensive resources to be effective. This inaccessibility is also further worsened by the ongoing COVID-19 pandemic, making the shift to a digital approach a sensible option. Among the available ASD therapies, parent-mediated interventions (PMIs) have a broad application and lower implementation cost. Hence, this systematic review aims to evaluate the potential that telehealth-based PMI holds and explore its feasibility throughout the COVID-19 pandemic. To build up this study, a systematic search through PubMed, Scopus, ProQuest, Wiley, and Cochrane was performed until 14 January 2021. Using the preferred Reporting Items for Systematic Review and Meta-Analysis guidelines, we ultimately included six studies in the review. Each study was evaluated utilizing the Cochrane Risk of Bias (ROB)-2 tool. Generally, parents&#039; outcomes (knowledge, satisfaction, and compliance) were higher in intervention group (E-learning) compared to control (standard treatment or wait-list). Children also showed some improvements in social skill, communication skill, and intelligence after receiving the treatment. In addition, coaching or therapist sessions were found to be crucial as adjuvant to support parents during the intervention. In conclusion, internet-based parent-mediated interventions are promising and recommended for managing ASD patients, in the face of pandemic. However, more variety in study locations is also needed, particularly in low- and middle-income countries, to tackle the knowledge and clinical application gap. Further research should be conducted with a uniform measurement tool to achieve the same perception and reliable pooled analysis.
AN  - 36291419
AU  - Yosep,
AU  - I.
AU  - Prayogo,
AU  - S.
AU  - A.
AU  - Kohar,
AU  - K.
AU  - Andrew,
AU  - H.
AU  - Mardhiyah,
AU  - A.
AU  - Amirah,
AU  - S.
AU  - Maulana,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/children9101483
L1  - internal-pdf://0290072789/Yosep-2022-Managing Autism Spectrum Disorder i.pdf
PY  - 2022
SP  - 28
T2  - Children
TI  - Managing Autism Spectrum Disorder in the Face of Pandemic Using Internet-Based Parent-Mediated Interventions: A Systematic Review of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36291419
UR  - https://mdpi-res.com/d_attachment/children/children-09-01483/article_deploy/children-09-01483-v2.pdf?version=1664445540
VL  - 9
ER  -
TY  - JOUR
AB  - LAY ABSTRACT: Nearly three out of four autistic people experience mental health problems such as stress, anxiety or depression. The research already done does not guide us on how best to prevent or treat mental health problems for autistic people. Our aim was to look at the benefits and harms of different interventions on mental health outcomes in autistic people. We searched all the published randomised controlled trials (RCTs) about interventions for mental health conditions in autistic people until 17 October 2020. We also searched for RCTs that were not published in peer-reviewed journals. These were obtained from registers of clinical trials online. We then combined the information from all these trials using advanced statistical methods to analyse how good the interventions are. Seventy-one studies (3630 participants) provided information for this research. The studies reported how participants were responding to the intervention for only a short period of time. The trials did not report which interventions worked for people with intellectual disability. In people without intellectual disability, some forms of cognitive behavioural therapy and mindfulness therapy may be helpful. However, further research is necessary. Many trials used medications to target core features of autism rather than targeting mental health conditions, but these medications did not help autistic people. Until we have more evidence, treatment of mental health conditions in autistic people should follow the evidence available for non-autistic people. We plan to widely disseminate the findings to healthcare professionals through medical journals and conferences and contact other groups representing autistic people.
AN  - 35957523
AU  - Linden,
AU  - A.
AU  - Best,
AU  - L.
AU  - Elise,
AU  - F.
AU  - Roberts,
AU  - D.
AU  - Branagan,
AU  - A.
AU  - Tay,
AU  - Y.
AU  - B.
AU  - E.
AU  - Crane,
AU  - L.
AU  - Cusack,
AU  - J.
AU  - Davidson,
AU  - B.
AU  - Davidson,
AU  - I.
AU  - Hearst,
AU  - C.
AU  - Mandy,
AU  - W.
AU  - Rai,
AU  - D.
AU  - Smith,
AU  - E.
AU  - Gurusamy,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/13623613221117931
L1  - internal-pdf://0586056652/Linden-2022-Benefits and harms of intervention.pdf
PY  - 2022
SP  - 13623613221117931
T2  - Autism
TI  - Benefits and harms of interventions to improve anxiety, depression, and other mental health outcomes for autistic people: A systematic review and network meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35957523
UR  - https://journals.sagepub.com/doi/pdf/10.1177/13623613221117931
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Children and adolescents with intellectual disabilities (IDs) tend to have lower levels of physical activity and poorer mental health than their typically developing peers. Studies on the effects of physical activity on the mental health of children with IDs using the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework are scarce. 

**METHODS**
A systematic literature review using six databases (CINAHL, Eric, PsycINFO, PubMed, SPORTDiscus, and Web of Science) was conducted from January 2000 to September 2021. Studies reporting at least one physical activity intervention and mental health outcome in children and adolescents with IDs aged between 5 and 17 years were included in the meta-analysis. Preferred Reporting Items for Systematic Review and Meta-Analysis guideline, Comprehensive Meta-Analysis, and the RE-AIM framework were utilized. 

**RESULTS**
A total of 15 studies that met the inclusion criteria were included in the meta-analysis. The effects of physical activity on mental health in children and adolescents with IDs were significant and large (Hedges&#039; g = 0.897, p &lt; 0.01), with medium effects on psychological health (Hedges&#039; g = 0.542, p &lt; 0.01) and large effects on cognitive function (Hedges&#039; g = 1.236, p &lt; 0.01). Randomized controlled trial (RCT) design and intervention components (&gt; 120 minutes per week, therapeutic, and aerobic exercise) demonstrated the strongest effects. Moreover, study background (publication year, study location, and sample size), participant characteristics (age and sex), and Maintenance (RE-AIM framework) moderated the effects of physical activity on mental health. Based on the RE-AIM framework, there were higher proportions in the dimensions of Reach and Effectiveness than Adoption, Implementation, and Maintenance. 

**CONCLUSIONS**
Physical activity appears to have positive effects on mental health, including psychological health and cognitive function, in children and adolescents with IDs. Physical activity interventions using the RE-AIM framework are recommended to assess short- and long-term impacts and translate scientific evidence into practice. TRIAL REGISTRATION: The protocol for this meta-analysis was registered with PROSPERO ( CRD42021256543 ).
AN  - 35799257
AU  - Yang,
AU  - W.
AU  - Liang,
AU  - X.
AU  - Sit,
AU  - C.
AU  - H.
DB  - Alerts 6_2022.enl
DO  - /10.1186/s12966-022-01312-1
L1  - internal-pdf://0198562239/Yang-2022-Physical activity and mental health.pdf
PY  - 2022
SP  - 80
T2  - International Journal of Behavioral Nutrition &amp; Physical Activity
TI  - Physical activity and mental health in children and adolescents with intellectual disabilities: a meta-analysis using the RE-AIM framework
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35799257
UR  - https://ijbnpa.biomedcentral.com/track/pdf/10.1186/s12966-022-01312-1.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - We aimed to perform an umbrella review of systematic reviews and meta-analyses (SRMAs) of randomized clinical trials (RCT) of the effects of long-chain omega-3 fatty acid supplementation in pregnancy, lactation, and infancy. We searched PubMed, Scopus, and Web of Science to November 2020. Two independent investigators extracted the information, evaluated the methodological quality of SRMAs using A Measurement Tool to Assess Systematic Reviews-2 (AMSTAR2), and rated the certainty of evidence using the Grades of Recommendation, Assessment, Development and Evaluation (GRADE) approach. Either a fixed-effects or a random-effects model was used to recalculate the effect sizes and 95%CIs, depending on the number of trials. Overall, 28 SRMAs of RCTs, reporting 124 outcomes from 672 RCTs with 273,523 participants were considered eligible for the present umbrella review. Our results demonstrated evidence of moderate to high certainty that omega-3 supplementation reduced the risk of pre-eclampsia and low-birth weight and improved head circumference when used in pregnant women, and reduced severe retinopathy of prematurity and cholestasis when used in infancy. There were also favorable effects on preterm delivery, pre-natal and post-partum depression, glycemic control and inflammation markers in pregnant women, and sensitization to peanuts, positive skin prick tests, anthropometric measures, language development, visual acuity, and duration of ventilation in infants (GRADE = low). Our findings suggested that omega-3 supplementation during pregnancy can exert favorable effects against pre-eclampsia, low-birth weight, pre-term delivery, and post-partum depression, and can improve anthropometric measures, immune system, and visual activity in infants and cardiometabolic risk factors in pregnant mothers.
AN  - 35104631
AU  - Firouzabadi,
AU  - F.
AU  - D.
AU  - Shab-Bidar,
AU  - S.
AU  - Jayedi,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.phrs.2022.106100
L1  - internal-pdf://2967272145/The effects of omega-3 polyunsaturated fa-2022.pdf
PY  - 2022
SP  - 106100
T2  - Pharmacological Research
TI  - The effects of omega-3 polyunsaturated fatty acids supplementation in pregnancy, lactation, and infancy: An umbrella review of meta-analyses of randomized trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35104631
UR  - https://www.sciencedirect.com/science/article/pii/S1043661822000457?via%3Dihub
VL  - 177
ER  -
TY  - JOUR
AB  - Among the distraction techniques used for the non-pharmacological management of acute pediatric pain, one of the most performed is clown therapy. Despite the presence in the literature of some systematic reviews that evaluate its effectiveness, none of them examines its outcomes on procedural pain which has therefore been investigated in this study. 

The literature search for randomized controlled trials (RCTs) was performed on the Cochrane Library, MEDLINE, EMBASE, CINAHL, PsycINFO, Web of Science, and Scopus over a time frame ranging from each database setup date to 31 July 2021. The primary outcome was the procedural pain of children. We used the Cochrane Risk of Bias tool to assess the risk of bias of the included studies. Six RCTs were selected for this review, which included a total of 517 pediatric subjects. Children undergoing clown therapy during the venipuncture or peripheral vein cannulation procedure reported less pain than those exposed to the standard of care (SMD = -0.55; 95% CI: -1.23, 0.13) but the result was not found to be statistically significant. School-aged children and adolescent reported significantly less pain (SMD = -0.51; 95% CI: -0.92, -0.09). Compared to the standard of care, children&#039;s anxiety was significantly lower with clown therapy (SMD = -0.97; 95% CI: -1.38, -0.56). 

CONCLUSION: Clown therapy seems effective in reducing procedural pain in children, particularly for older age groups, but due to poor methodological quality and the high risk of bias of the studies included, the results obtained should be considered with caution. WHAT IS KNOWN: * Clown therapy is one of the most used techniques in the non-pharmacological management of acute pediatric pain. * Laughter physiologically stimulates the production of beta-endorphins, substances with an effect similar to opiates. WHAT IS NEW: * Clown therapy seems effective in reducing procedural pain and anxiety in children. * The intervention in school-age children or adolescents produces a statistically significant decrease in the symptom.
AN  - 35294645
AU  - Fusetti,
AU  - V.
AU  - Re,
AU  - L.
AU  - Pigni,
AU  - A.
AU  - Tallarita,
AU  - A.
AU  - Cilluffo,
AU  - S.
AU  - Caraceni,
AU  - A.
AU  - T.
AU  - Lusignani,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00431-022-04440-9
L1  - internal-pdf://3333515189/Clown therapy for procedural pain in chil-2022.pdf
PY  - 2022
SP  - 16
T2  - European Journal of Pediatrics
TI  - Clown therapy for procedural pain in children: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35294645
UR  - https://link.springer.com/content/pdf/10.1007/s00431-022-04440-9.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - To elucidate possible additive effects of electroencephalogram-based neurofeedback (EEG-NF) on medications against the core symptoms of attention-deficit/hyperactivity disorder (ADHD), randomized controlled trials (RCTs) were retrieved from electronic databases including PubMed, EMBASE, ClinicalKey, Cochrane CENTRAL, ScienceDirect, and ClinicalTrials.gov from inception to March 2022. The primary outcomes were changes in ADHD symptoms (i.e., global, inattention, hyperactivity/impulsivity) assessed with validated rating scales, while secondary outcome was all-cause discontinuation rate. Meta-analysis of five RCTs involving 305 participants [Median age = 9.285 years (range 8.6-11.05)] with a median follow-up of 12 weeks showed additive effects of EEG-NF on medications from parents&#039; observations against ADHD global symptoms (Hedges&#039; g = 0.2898, 95%CI [0.0238; 0.5557]) and inattention symptoms (Hedges&#039; g = 0.3274, 95%CI [0.0493; 0.6055]). However, additive effects failed to sustain six months after EEG-NF intervention. Besides, there was no difference in improvement of hyperactivity/impulsivity from parents&#039; observation, attentional performance, and all-cause discontinuation rate between the two groups. Our results supported additional benefits of combining EEG-NF with medications compared to medication alone in treating global symptoms and symptoms of inattention in ADHD patients. Nevertheless, given a lack of evidence showing a correlation between underlying physiological changes and small effect sizes in our preliminary results, further studies are warranted to support our findings.
AN  - 36437272
AU  - Lin,
AU  - F.
AU  - L.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Wang,
AU  - M.
AU  - Y.
AU  - Chung,
AU  - W.
AU  - Tzang,
AU  - R.
AU  - F.
AU  - Chiu,
AU  - H.
AU  - J.
AU  - Cheng,
AU  - Y.
AU  - C.
AU  - Tu,
AU  - K.
AU  - Y.
DB  - Alerts 6_2022.enl
DO  - /10.1038/s41598-022-23015-0
L1  - internal-pdf://1011928933/Lin-2022-Additive effects of EEG neurofeedback.pdf
PY  - 2022
SP  - 20401
T2  - Scientific Reports
TI  - Additive effects of EEG neurofeedback on medications for ADHD: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36437272
UR  - https://www.nature.com/articles/s41598-022-23015-0.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - Dysregulated anger, and its common behavioral urge, aggression, pose substantial costs to public health and society. Though some studies have shown DBT to be efficacious in treating aggression and anger dyscontrol, the overall effects of DBT on these outcomes are unknown.

To address this limitation, a systematic review with metaanalysis was conducted on 34 studies (N = 2536) published in PsycINFO and PubMed between January 1994 and February 2022 assessing the effect of DBT on anger and/or aggression. Included studies were empirical research articles published in a peer-reviewed journal and assessed the delivery of DBT on quantitative outcome measures of anger or aggression. Included studies delivered the standard outpatient DBT program or DBT adapted for the population and treatment setting, though all studies included the core components of DBT. Risk of publication bias was assessed. 

Results demonstrated that DBT significantly reduced anger (Hedge&#039;s G = -0.21, 95% CI [-0.32, - 0.11]) independent of study design and participant variables, though longer treatment duration was associated with greater reductions in anger. There was also a non-significant trend for DBT in reducing aggression (Hedge&#039;s G = -0.10, 95% CI [-0.21, 0.00]). 

Findings from this study suggest that DBT demonstrates efficacy in reducing dysregulated anger transdiagnostically.
AN  - WOS:000804559900002
AU  - Ciesinski,
AU  - N.
AU  - K.
AU  - Sorgi-Wilson,
AU  - K.
AU  - M.
AU  - Cheung,
AU  - J.
AU  - C.
AU  - Chen,
AU  - E.
AU  - Y.
AU  - McCloskey,
AU  - M.
AU  - S.
DB  - Alerts 6_2022.enl
DO  - 10.1016/j.brat.2022.104122
L1  - internal-pdf://0859946363/1-s2.0-S0005796722000936-main.cleaned.pdf
PY  - 2022
SP  - 12
T2  - Behaviour Research and Therapy
TI  - The effect of dialectical behavior therapy on anger and aggressive behavior: A systematic review with meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000804559900002
UR  - https://www.sciencedirect.com/science/article/pii/S0005796722000936?via%3Dihub
VL  - 154
ER  -
TY  - JOUR
AB  - **Purpose:** 
We conducted a rapid evidence review to explore the benefits and harms of digital cognitive-behavioral therapy (dCBT) and the barriers to and facilitators of implementing dCBT for adolescents. 

**Method(s):** 
We searched MEDLINE, PsycINFO, CENTRAL through December 6, 2021, for controlled trials conducted in settings highly applicable to the United States. Additionally, we searched relevant systematic reviews for eligible studies. Results were summarized qualitatively. 

**Result(s):** 
We included 12 trials (n = 1,575) that examined the effects of nine dCBT programs. Overall, dCBT was slightly superior to comparators in improving depression symptoms immediately post-intervention, but not at a longer follow-up. The use of dCBT did not appear to result in an increased risk for suicidal attempts or ideation; however, the number of events was very small. Potential barriers to implementing/maintaining dCBT are challenges engaging/retaining patients, developing infrastructure, and training therapists to facilitate dCBT. Data on harms or unintended negative consequences were not reported in the included studies. 

**Conclusion(s):** 
A limited body of evidence suggests that dCBT programs might outperform control interventions for reducing depressive symptoms immediately post-intervention, but not at a longer follow-up. The safety of dCBT programs for adolescents with depression is understudied. Copyright &copy; 2022 Society for Adolescent Health and Medicine
AN  - 2017123311
AU  - Ivlev,
AU  - I.
AU  - Beil,
AU  - T.
AU  - L.
AU  - Haynes,
AU  - J.
AU  - S.
AU  - Patnode,
AU  - C.
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jadohealth.2022.01.220
L1  - internal-pdf://2765800259/Rapid Evidence Review of Digital Cognitiv-2022.pdf
PY  - 2022
T2  - Journal of Adolescent Health.
TI  - Rapid Evidence Review of Digital Cognitive-Behavioral Therapy for Adolescents With Depression
UR  - https://www.elsevier.com/locate/jadohea
UR  - https://www.sciencedirect.com/science/article/pii/S1054139X22002798?via%3Dihub
ER  -
TY  - JOUR
AB  - **Background and aims** 
Play-based interventions are used ubiquitously with children with social, communication, and language needs but the impact of these interventions on the mental health of this group of children is unknown. Despite their pre-existing challenges, the mental health of children with developmental language disorder (DLD) and autism spectrum disorder (ASD) should be given equal consideration to the other more salient features of their condition. To this aim, a systematic literature review with meta-analysis was undertaken to assess the impact of play-based interventions on mental health outcomes from studies of children with DLD and ASD, as well as to identify the characteristics of research in this field. 

**Methods** 
The study used full systematic review design reported to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines (PRISMA prisma-statement.org) with pre-specified inclusion criteria and explicit, transparent and replicable methods at each stage of the review. The study selection process involved a rigorous systematic search of seven academic databases, double screening of abstracts, and full-text screening to identify studies using randomised controlled trial (RCT) and quasi-experimental (QE) designs to assess mental health outcomes from interventions supporting children with DLD and ASD. For reliability, data extraction of included studies, as well as risk of bias assessments were conducted by two study authors. Qualitative data were synthesised narratively and quantified data were used in the metaanalytic calculation. 

**Main contribution** A total of 2,882 papers were identified from the literature search which were double screened at the abstract (n = 1,785) and full-text (n = 366) levels resulting in 10 papers meeting the criteria for inclusion in the review. There were 8 RCTs and 2 QEs using 7 named play-based interventions with ASD participants only. Meta-analysis of 5 studies addressing positive mental health outcomes (e.g. positive affect and emotional functioning) found a significant overall intervention effect (Cohen&#039;s d = 1.60 (95% CI [0.37, 2.82], p = 0.01); meta-analysis of 6 studies addressing negative mental health outcomes (e.g., negative affect, internalising and externalising problems) found a non-significant overall intervention effect (Cohen&#039;s d = 0.04 -0.17 (95% CI [-0.04, 0.51], p = 0.88). 

**Conclusions** 
A key observation is the diversity of study characteristics relating to study sample size, duration of interventions, study settings, background of interventionists, and variability of specific mental health outcomes. Play-based interventions appear to have a beneficial effect on positive, but not negative, mental health in children with ASD. There are no high quality studies investigating the efficacy of such interventions in children with DLD. Implications This review provides good evidence of the need for further research into how commonly used play-based interventions designed to support the social, communication, and language needs of young people may impact the mental health of children with ASD or DLD.
AN  - WOS:000766604000001
AU  - Francis,
AU  - G.
AU  - Deniz,
AU  - E.
AU  - Torgerson,
AU  - C.
AU  - Toseeb,
AU  - U.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/23969415211073118
L1  - internal-pdf://1245337621/Play-based interventions for mental healt-2022.pdf
PY  - 2022
SP  - 44
T2  - Autism &amp; Developmental Language Impairments
TI  - Play-based interventions for mental health: A systematic review and meta-analysis focused on children and adolescents with autism spectrum disorder and developmental language disorder
UR  - &lt;Go to ISI&gt;://WOS:000766604000001
VL  - 7
ER  -
TY  - JOUR
AB  - BACKGROUND: Mental health difficulties in children and adolescents are highly prevalent; however, only a minority receive adequate mental health care. Internet-delivered interventions offer a promising opportunity to increase access to mental health treatment. Research has demonstrated their effectiveness as a treatment for depression and anxiety in adults. This work provides an up-to-date examination of the available intervention options and their effectiveness for children and young people (CYP). 

OBJECTIVE: In this systematic review and meta-analysis, we aimed to determine the evidence available for the effectiveness of internet-delivered interventions for treating anxiety and depression in CYP. METHODS: Systematic literature searches were conducted throughout November 2020 using PubMed, PsycINFO, and EBSCO academic search complete electronic databases to find outcome trials of internet-delivered interventions treating symptoms of anxiety and/or depression in CYP by being either directly delivered to the CYP or delivered via their parents. Studies were eligible for meta-analysis if they were randomized controlled trials. Risk of bias and publication biases were evaluated, and Hedges g between group effect sizes evaluating intervention effects after treatment were calculated. Meta-analyses used random-effects models as per protocol. 

RESULTS: A total of 23 studies met the eligibility criteria for the systematic review, of which 16 were included in the meta-analyses, including 977 participants in internet-delivered treatment conditions and 1008 participants in control conditions across 21 comparisons. Random-effects models detected a significant small effect for anxiety symptoms (across 20 comparisons; Hedges g=-0.25, 95% CI -0.38 to -0.12; P&lt;.001) and a small but not significant effect for depression (across 13 comparisons; Hedges g=-0.27, 95% CI -0.55 to 0.01; P=.06) in favor of internet-delivered interventions compared with control groups. Regarding secondary outcomes, there was a small effect of treatment across 9 comparisons for impaired functioning (Hedges g=0.52, 95% CI 0.24-0.80; P&lt;.001), and 5 comparisons of quality of life showed no effect (Hedges g=-0.01, 95% CI -0.23 to 0.21; P=.94). 

CONCLUSIONS: The results show that the potential of internet-delivered interventions for young people with symptoms of anxiety or depression has not been tapped into to date. This review highlights an opportunity for the development of population-specific interventions and their research to expand our current knowledge and build an empirical base for digital interventions for CYP. 

TRIAL REGISTRATION: PROSPERO CRD42020220171; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=220171.
AN  - 35551071
AU  - Eilert,
AU  - N.
AU  - Wogan,
AU  - R.
AU  - Leen,
AU  - A.
AU  - Richards,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/33551
L1  - internal-pdf://0613948557/Internet-Delivered Interventions for Depr-2022.pdf
PY  - 2022
SP  - e33551
T2  - JMIR Pediatrics and Parenting
TI  - Internet-Delivered Interventions for Depression and Anxiety Symptoms in Children and Young People: Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35551071
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9136650/pdf/pediatrics_v5i2e33551.pdf
VL  - 5
ER  -
TY  - JOUR
AB  - To evaluate the evidences related to the effectiveness of neurofeedback treatment for children and adolescent with attention-deficit/hyperactivity disorder (ADHD) based on the most-proximal raters. 

A systematic review of randomized control trials (RCTs) was carried out across multiple databases. the primary outcome measure was the most proximal ratings of ADHD symptoms in subjects. Conner&#039;s Parent Rating Scale (CPRS), Conner&#039;s Teacher Rating Scale (CTRS), and ADHD Rating Scale (ADHD-RS- are considered as primary outcomes. 

Seventeen trials met inclusion criteria (including 1211 patients). Analysis showed that there was no significant benefit of neurofeedback treatment compared with other treatments or control conditions [weighted mean difference/CI = HI-P: -0.02 (-0.26, 0.21), HI-T: 0.01 (-0.46, 0.48), weighted mean difference/CI = I-P: 0.00 (-0.23, 0.23), I-P: 0.12 (-0.14, 0.38)]. 

The results provide preliminary evidence that neurofeedback treatment is no efficacious clinical method for ADHD and suggest that more RTCs are needed to compare common treatment .
AN  - 35068368
AU  - Rahmani,
AU  - E.
AU  - Mahvelati,
AU  - A.
AU  - Alizadeh,
AU  - A.
AU  - Mokhayeri,
AU  - Y.
AU  - Rahmani,
AU  - M.
AU  - Zarabi,
AU  - H.
AU  - Hassanvandi,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/13554794.2022.2027456
L1  - internal-pdf://2904139356/Is neurofeedback effective in children wi-2022.pdf
PY  - 2022
SP  - 1-12
T2  - Neurocase
TI  - Is neurofeedback effective in children with ADHD? A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35068368
UR  - https://www.tandfonline.com/doi/full/10.1080/13554794.2022.2027456
ER  -
TY  - JOUR
AB  - **Objective**
The aim of this study was to analyze the randomised controlled trials that explored the effect of kangaroo mother care on physiological stress parameters of premature infants. 

**Method(s)**
Two independent researchers performed a systematic review of indexed studies in PubMed, Embase, CINAHL, Cochrane and Scopus. We included data from randomized controlled trials measuring the effects of kangaroo care compared to standard incubator care on physiological stress outcomes, defined as oxygen saturation, body temperature, heart rate and respiratory rate. The PRISMA model was used to conduct data extraction. We performed a narrative synthesis of all studies and a meta-analysis when data were available from multiple studies that compared the same physiological parameters with the kangaroo method as an intervention and controls and used the same outcome measures. 

**Result(s)**
Twelve studies were eligible for inclusion in this meta-analysis. According to statistical analysis, the mean respiratory rate of preterm infants receiving KMC was lower than that of infants receiving standard incubator care (MD, -3.50; 95% CI, -5.17 to -1.83; p &lt;0.00001). Infants who received kangaroo mother care had a higher mean heart rate, oxygen saturation and temperature, although these results were not statistically significant. 

**Conclusion(s)**
Current evidence suggests that kangaroo care in the neonatal intensive care unit setting is a safe method that may have a significant effect on some of the physiological parameters of stress in preterm infants. However, due to clinical heterogeneity, further studies are needed to assess the effects of physiological stress in the neonatal intensive care unit on the development of preterm infants. Copyright &copy; 2022 by the authors. Licensee MDPI, Basel, Switzerland.
AN  - 2015197677
AU  - Canadas,
AU  - D.
AU  - C.
AU  - Perales,
AU  - A.
AU  - B.
AU  - Martinez,
AU  - R.
AU  - G.
AU  - Casado-Belmonte,
AU  - M.
AU  - P.
AU  - Carreno,
AU  - T.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph19010583
L1  - internal-pdf://1705546421/Effects of Kangaroo Mother Care in the NI-2022.pdf
PY  - 2022
T2  - International Journal of Environmental Research and Public Health
TI  - Effects of Kangaroo Mother Care in the NICU on the Physiological Stress Parameters of Premature Infants: A Meta-Analysis of RCTs
UR  - https://www.mdpi.com/1660-4601/19/1/583/pdf
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-19-00583/article_deploy/ijerph-19-00583.pdf
VL  - 19(1) (no pagination)
ER  -
TY  - JOUR
AB  - **Background** 
The use of distance-based interventions (DBIs) to reduce suicidal ideation and behaviours are an increasingly relevant form of intervention. DBIs are more affordable, scalable and available than traditional face-To-face interventions, helping to narrow the gap between needed and provided care. 

**Aims** 
To evaluate the overall effectiveness of DBIs against suicidal ideation and behaviours. 

**Method** 
We systematically searched Web of Science, Scopus and PubMed for all DBIs primarily aimed at reducing suicidal ideation and behaviours. Data were analysed with a robust variance estimation corrected, multi-level meta-Analysis. 

**Results** 
We found 38 studies, reporting 110 outcomes. Effectiveness in reducing suicidal ideation was low (standardised mean difference-0.174, 95% CI-0.238 to-0.110). DBIs were significantly less effective against suicidal behaviours than against suicidal ideation, although still effective (standardised mean difference-0.059, 95% CI-0.087 to-0.032). Human involvement had no significant effect on effectiveness. 

**Conclusions**
Despite low effectiveness, DBIs might play a role in large-scale prevention efforts against suicidal ideation within a stepped care approach. Further, DBIs may be helpful in expanding mental health services in low-and middle-income countries with otherwise limited access to mental healthcare. Although the evidence for DBIs efficacy is well grounded, the technical and scientific evaluation of DBIs regarding their set up, functionality and components needs to be addressed in future studies. Copyright &copy; The Author(s), 2022. Published by Cambridge University Press on behalf of the Royal College of Psychiatrists.
AN  - 2019633999
AU  - Schmeckenbecher,
AU  - J.
AU  - Rattner,
AU  - K.
AU  - Cramer,
AU  - R.
AU  - J.
AU  - Plener,
AU  - P.
AU  - L.
AU  - Baran,
AU  - A.
AU  - Kapusta,
AU  - N.
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/bjo.2022.526
L1  - internal-pdf://3423264079/Schmeckenbecher-2022-Effectiveness of distance.pdf
PY  - 2022
T2  - BJPsych Open
TI  - Effectiveness of distance-based suicide interventions: Multi-level meta-Analysis and systematic review
UR  - https://www.cambridge.org/core/journals/bjpsych-open
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/31752786970DFD642CB6C6CBFF91DA23/S2056472422005269a.pdf/div-class-title-effectiveness-of-distance-based-suicide-interventions-multi-level-meta-analysis-and-systematic-review-div.pdf
VL  - 8(4) (no pagination)
ER  -
TY  - JOUR
AB  - **Sammanfattning och slutsatser**
SBU har granskat det vetenskapliga underlaget f&ouml;r hormonbehandling, pubertetsh&auml;mmande och k&ouml;nskontr&auml;r, av barn och unga med k&ouml;nsdyfori.

- Det vetenskapliga underlaget r&auml;cker inte f&ouml;r att bed&ouml;ma effekter på k&ouml;nsdysfori, psykosociala f&ouml;rhållanden, kognitiv funktion, kroppsmått, kroppssammans&auml;ttning eller &auml;mnesoms&auml;ttning. av pubertetsh&auml;mmande eller k&ouml;nskontr&auml;r hormonbehandling hos barn och ungdomar med k&ouml;nsdysfori.

- Det finns ett visst st&ouml;d på gruppnivå f&ouml;r att pubertetsh&auml;mmande hormonbehandling (GnRH) f&ouml;rlångsammar den benuppbyggnad som kan f&ouml;rv&auml;ntas ske under den f&ouml;ljande puberteten (låg tillf&ouml;rlitlighet) men att den vid starten av behandling uppnådda bent&auml;theten bibehålls (låg tillf&ouml;rlitlighet).

- Det finns ett visst st&ouml;d på gruppnivå f&ouml;r att ungdomar som fått pubertetsh&auml;mmande hormonbehandling, under en f&ouml;ljande k&ouml;nskontr&auml;r hormonbehandling med &ouml;strogen eller testosteron, återh&auml;mtar bent&auml;theten (låg tillf&ouml;rlitlighet), men det går inte att avg&ouml;ra om bent&auml;theten på sikt kommer helt upp i nivå med unga i den omgivande befolkningen.

- Det vetenskapliga underlaget r&auml;cker inte f&ouml;r att bed&ouml;ma hur ofta ungdomar, efter det att psykologisk/psykiatrisk och medicinsk utredning har inletts på grund av psykosociala problem som har ansetts bero på k&ouml;nsdysfori, v&auml;ljer att inte påb&ouml;rja eller att frivilligt avbryta pubertetsh&auml;mmande eller k&ouml;nskontr&auml;r hormonbehandling.

**Behov av uppf&ouml;ljning och forskning**

Sammanhållna data som beskriver f&ouml;rloppet f&ouml;r dem som s&ouml;ker f&ouml;r och får en k&ouml;nsdysforidiagnos i Sverige &auml;r &ouml;nskv&auml;rda.

Randomiserade studier av hormonbehandling vid k&ouml;nsdysfori saknas. Sådana studier &auml;r &ouml;nskv&auml;rda men troligen svåra att utf&ouml;ra.

De observationsstudier d&auml;r man gjort m&auml;tningar f&ouml;re och efter start av behandling &auml;r vanligen analyserade på gruppnivå Det vore &ouml;nskv&auml;rt att också f&ouml;r&auml;ndringar hos de enskilda personerna analyseras liksom att man f&ouml;rutom medelv&auml;rden också visar f&ouml;rdelningen av v&auml;rden i de studerade grupperna.

Utgångspunkt i studierna b&ouml;r vara pubertetsstadium (biologisk mognad) och inte enbart kronologisk ålder.

Observationer under l&auml;ngre tid &auml;r &ouml;nskv&auml;rda, s&auml;rskilt n&auml;r det g&auml;ller återh&auml;mtning av bent&auml;thet vid k&ouml;nskontr&auml;r hormonbehandling efter pubertetsh&auml;mmande hormonbehandling, psykosociala effekter och &auml;ndrad uppfattning om k&ouml;nsidentitet eller avbrott av behandling.

Studier under l&auml;ngre tid av personer som avslutar pubertetsh&auml;mmande hormonbehandling utan att forts&auml;tta med k&ouml;nskontr&auml;r hormonbehandling &auml;r &ouml;nskv&auml;rda.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - Har ikke DOI
L1  - internal-pdf://1647370078/hormonbehandling-vid-konsdysfori_barn-och-unga.pdf
PY  - 2022
TI  - Hormonbehandling vid k&ouml;nsdysfori &ndash; barn och unga
ER  -
TY  - JOUR
AB  - This systematic review of reviews is the first to summarize peer tutoring outcomes for students with or at-risk for emotional and behavioral disorders (EBD). Eleven narrative literature reviews, three systematic reviews, and two meta-analyses of peer tutoring interventions that met inclusion criteria were summarized. Participants across the 16 reviews included more than 2,404 students with or at-risk for EBD in pre-kindergarten through grade 12 across 73 individual, unduplicated studies. Findings support the efficacy of peer tutoring for students with or at-risk for EBD regarding academic and behavioral outcomes. Lessons learned, and implications for research and practice derived from these reviews are provided.
AN  - 36154492
AU  - Bowman-Perrott,
AU  - L.
AU  - Ragan,
AU  - K.
AU  - Boon,
AU  - R.
AU  - T.
AU  - Burke,
AU  - M.
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/01454455221118359
L1  - internal-pdf://2752096434/01454455221118359.cleaned.pdf
PY  - 2022
SP  - 1454455221118359
T2  - Behavior Modification
TI  - Peer Tutoring Interventions for Students With or At-Risk for Emotional and Behavioral Disorders: A Systematic Review of Reviews
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36154492
ER  -
TY  - JOUR
AB  - Due to the unfamiliarity of the surroundings, children having surgery endure worry and tension. Untreated anxiety in children impairs postoperative healing and causes changes in postoperative behavior. The purpose of this review was to determine the efficacy of distraction therapies on anxiety in children undergoing surgery. The systematic review was reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses standards. PubMed via MEDLINE, CINAHL, ProQuest, Web of Science, and the Cochrane Central Register of Controlled Trials were used to find relevant trials. Full-text papers published in English from January 1, 2000 to December 31, 2021 were included. Children undergoing surgery aged 1 to 18 years were included. A data extraction form was created to extract data from the selected studies. According to the Cochrane risk of bias assessment tool, studies were classified as &quot;low risk, &quot; &quot;high risk, &quot; or &quot;unclear risk. &quot; Review Manager software was used to do a quantitative meta-analysis. Thirteen studies looked at the effect of distraction intervention on children. Nine of them were selected for meta-analysis. The distraction interventions included in this review were: handheld video game, play dough and play with blocks and puzzles, tablet-based interactive distraction, animated video, painting and storytelling, age-appropriate video, distraction with video glasses, watching a movie, and bringing favorite toy during hospital stay. Meta-analysis showed that distraction interventions are effective on preoperative anxiety in children (standardized mean difference = -17.07, 95% confidence interval: 27.11-7.02, p = 0.0009).
AN  - WOS:000891224800005
AU  - Mathias,
AU  - E.
AU  - G.
AU  - Pai,
AU  - M.
AU  - S.
AU  - Bramhagen,
AU  - A.
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1055/s-0042-1757967
L1  - internal-pdf://4163030105/Mathias-Effect of Distraction Interventions on.pdf
PY  - 2022
SP  - 9
T2  - Journal of Health and Allied Sciences Nu
TI  - Effect of Distraction Interventions on Anxiety in Children Undergoing Surgery: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000891224800005
UR  - https://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0042-1757967.pdf
ER  -
TY  - JOUR
AB  - OBJECTIVE: 
This systematic review explored the effectiveness of using physical activity (PA) interventions to enhance psychological well-being and reduce psychological ill-being (e.g., anxiety, depression) in children aged six to 11 years old from the general population. 

METHODS: 
Electronic databases were searched for studies published between January 2005 and June 2020: Web of Science, ProQuest Psychology Journals, PsycINFO, Pub Med, ASSIA, CINHAL PLUS, SPORTDiscus, EMBASE and Wiley Online Library. Search terms included &quot;physical activity intervention&quot;, &quot;psychological well-being&quot;, and &quot;child*&quot;. After removing duplicates, 11,390 studies were independently screened by two authors based on inclusion/exclusion criteria and assessed for risk of bias. 

RESULTS: 
A total of 23 studies were narratively synthesised and categorised into four domains: Quality of Life (QOL), body image, self-esteem, and psychological ill-being. Evidence was provided for the impact of PA interventions in improving QOL, body image and self-esteem. Despite the positive effect on psychological well-being, evidence for a reduction in the frequency and severity of symptoms associated with psychological ill-being in children is less clear. 

CONCLUSIONS: 
Reviewed studies support the use of PA interventions in enhancing the psychological well-being of children in school and community settings. More research is warranted to understand the impact of PA interventions on reducing psychological ill-being in children from the general population.
AN  - 35995884
AU  - Hale,
AU  - G.
AU  - E.
AU  - Colquhoun,
AU  - L.
AU  - Lancastle,
AU  - D.
AU  - Lewis,
AU  - N.
AU  - Tyson,
AU  - P.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/cch.13048
L1  - internal-pdf://2029550760/Hale-2022-Physical Activity Interventions for.pdf
PY  - 2022
SP  - 22
T2  - Child: Care, Health &amp; Development
TI  - Physical Activity Interventions for the Mental Health of Children: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35995884
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cch.13048?download=true
VL  - 22
ER  -
TY  - JOUR
AB  - **Background** 
This study reviews the evidence on ecological momentary interventions (EMIs) for managing and preventing suicidal thoughts and behaviors. 

**Methods** 
This review follows the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Its protocol was registered in the PROSPERO database. We conducted a systematic literature search of five databases: PubMed, EMBASE, Web of Science, PsycInfo, and Cochrane library. The most recent search date was 10 September 2021. 

**Results** 
After screening and full-text review, 27 studies were included, totaling 19 different interventions. Many of the available interventions have not yet been clinically tested. Those that have undergone effectiveness evaluation (10 interventions) showed good rates of effectiveness and feasibility, with some exceptions. The most widely used intervention model is the safety plan, which allows the user to implement coping and distracting strategies in case of suicidal ideation. 

**Conclusions** 
Ecological momentary interventions provide certain advantages, such as their wide availability, versatility, and potential for customization. These interventions can be useful complements to traditional care, especially in situations in which face-to-face care is not possible. Evidence on the effectiveness of such interventions is still scarce. Furthermore, barriers limiting implementation in clinical practice remain. The constant advance of technology means that these interventions have great potential for improvement in the coming years.
AN  - WOS:000766745900001
AU  - Jimenez-Munoz,
AU  - L.
AU  - Penuelas-Calvo,
AU  - I.
AU  - Diaz-Olivan,
AU  - I.
AU  - Gutierrez-Rojas,
AU  - L.
AU  - Baca-Garcia,
AU  - E.
AU  - Porras-Segovia,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1097/hrp.0000000000000331
L1  - internal-pdf://1366152579/Suicide Prevention in Your Pocket_ A Syst-2022.pdf
PY  - 2022
SP  - 85-99
T2  - Harvard Review of Psychiatry
TI  - Suicide Prevention in Your Pocket: A Systematic Review of Ecological Momentary Interventions for the Management of Suicidal Thoughts and Behaviors
UR  - &lt;Go to ISI&gt;://WOS:000766745900001
VL  - 30
ER  -
TY  - JOUR
AB  - **Purpose:** 
This study is a meta-analysis on the efficacy of eye movement desensitization and reprocessing (EMDR) in reducing Post-Traumatic Stress Disorder (PTSD) and co-occurring depression, and anxiety symptoms among forcibly displaced people. Methods: A search was followed by data extraction and assessment of risk of bias. Within- and between-conditions effect sizes of posttest and follow-up outcomes using a random effects model were examined, with heterogeneity and subgroup analyses. 

**Results:** 
Twenty-two studies (N = 1964) were included and seventeen (N = 1652) had complete data for the meta-analysis. There were medium to large effect size reductions on PTSD, depression, and anxiety within-conditions. EMDR was more effective than other conditions at posttest for PTSD symptoms but outcomes for the posttests and follow-ups for depression and anxiety were inconclusive. 

**Discussion:** 
EMDR effectively reduced PTSD symptoms, depression, and anxiety among forcibly displaced people. More studies with larger samples and better designs are needed.
AN  - WOS:000789232600001
AU  - Macgowan,
AU  - M.
AU  - J.
AU  - Naseh,
AU  - M.
AU  - Rafieifar,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/10497315221082223
L1  - internal-pdf://1925589436/Eye Movement Desensitization and Reprocessing.pdf
PY  - 2022
SP  - 15
T2  - Research on Social Work Practice
TI  - Eye Movement Desensitization and Reprocessing to Reduce Post-Traumatic Stress Disorder and Related Symptoms among Forcibly Displaced People: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000789232600001
UR  - https://journals.sagepub.com/doi/pdf/10.1177/10497315221082223
ER  -
TY  - JOUR
AB  - **Background**
The consequences for children born with birth defects and developmental disabilities encompassed by foetal alcohol spectrum disorder (FASD) are profound, affecting all areas of social, behavioural and cognitive functioning. Given the strong evidence for a core deficit in executive functioning, underpinned by impaired self-regulation skills, there has been a growing focus on the development of interventions that enhance or support the development of executive functions (EFs).

**Objectives**
The primary objective of this review is to synthesise the evidence for structured psychological interventions that explicitly aim to improve EF in children. The review also sought to ascertain if the effectiveness of interventions were influenced by characteristics of the intervention, participants or type of EF targeted by the intervention.

**Search Methods**
Sixteen databases, 18 grey literature search locations and 9 trial registries were systematically searched to locate eligible studies (up to December 2020). These searches were supplemented with reference harvesting, forward citation searching, hand searches of topic-relevant journals and contact with experts.

**Selection Criteria**
Studies were included in the review if they reported on an impact evaluation of a psychological intervention aiming to improve EF in children 3&ndash;16 years who either had confirmed prenatal alcohol exposure or a formal diagnosis falling under the umbrella term of FASDs. Eligible study designs included randomised controlled trials (RCTs) and quasi-experimental designs with either no treatment, wait list control or an alternative treatment as a comparison condition. Single-group pre-post designs were also included.

**Data Collection and Analysis**
Standard methodological procedures expected by the Campbell Collaboration were used at all stages of this review. Standardised mean differences (SMDs) were used to estimate intervention effects, which were combined with random effects meta-analysis (data permitting). Risk of bias was assessed using the Cochrane Risk of Bias Tool (RoB2) and Cochrane Risk of Bias in Non-Randomised Studies-Interventions tool (ROBINS-I).

**Main Results**
The systematic search identified 3820 unique records. After title/abstract and full-text screening, 11 eligible studies (reported in 21 eligible documents) were deemed eligible, with a combined 253 participants. Of the 11 studies, 6 were RCTs, 1 was a quasi-experiment and 4 were single-group pre-post intervention designs. All studies were rated as having an overall high or serious risk of bias, with some variation across domains for RCTs. For RCT and quasi-experimental studies, the overall effect of EF interventions on direct and indirect measures of EF generally favoured the experimental condition, but was not statistically significant. There was no difference between intervention and comparison groups on direct measures of auditory attention (k&thinsp;=&thinsp;3; SMD&thinsp;=&thinsp;0.06, 95% confidence interval [CI]&thinsp;=&thinsp;&minus;1.06, 1.18), visual attention (k&thinsp;=&thinsp;2; SMD&thinsp;=&thinsp;0.90, 95% CI&thinsp;=&thinsp;&minus;1.41, 3.21), cognitive flexibility (k&thinsp;=&thinsp;2; SMD&thinsp;=&thinsp;0.23, 95% CI&thinsp;=&thinsp;&minus;0.40, 0.86), attentional inhibition (k&thinsp;=&thinsp;2; SMD&thinsp;=&thinsp;0.04, 95% CI&thinsp;=&thinsp;&minus;0.58, 0.65), response inhibition (k&thinsp;=&thinsp;3; SMD&thinsp;=&thinsp;0.47, 95% CI&thinsp;=&thinsp;&minus;0.04, 0.99), or verbal working memory (k&thinsp;=&thinsp;1; d&thinsp;=&thinsp;0.6827; 95% CI&thinsp;=&thinsp;&minus;0.0196, 1.385). Significant heterogeneity was found across studies on measures of auditory attention and visual attention, but not for measures of cognitive flexibility, attentional inhibition or response inhibition. Available data prohibited further exploration of heterogeneity. There was no statistical difference between intervention and comparison groups on indirect measures of global executive functioning (k&thinsp;=&thinsp;2; SMD&thinsp;=&thinsp;0.21, 95% CI&thinsp;=&thinsp;&minus;0.40, 0.82), behavioural regulation (k&thinsp;=&thinsp;2; SMD&thinsp;=&thinsp;0.18, 95% CI&thinsp;=&thinsp;&minus;0.43, 0.79), or emotional control (k&thinsp;=&thinsp;3; SMD&thinsp;=&thinsp;0.01, 95% CI&thinsp;=&thinsp;&minus;0.33, 0.36). Effect sizes were positive and not significant for meta-cognition (k&thinsp;=&thinsp;1; SMD&thinsp;=&thinsp;0.23, 95% CI&thinsp;=&thinsp;&minus;0.72, 1.19), shifting (k&thinsp;=&thinsp;2; SMD&thinsp;=&thinsp;0.04, 95% CI&thinsp;=&thinsp;&minus;0.35, 0.43), initiation (k&thinsp;=&thinsp;1; SMD&thinsp;=&thinsp;0.04, 95% CI&thinsp;=&thinsp;&minus;0.40, 0.49), monitoring (k&thinsp;=&thinsp;1; SMD&thinsp;=&thinsp;0.25, 95% CI&thinsp;=&thinsp;&minus;0.20, 0.70) and organisation of materials (k&thinsp;=&thinsp;1; SMD&thinsp;=&thinsp;0.25, 95% CI&thinsp;=&thinsp;&minus;0.19, 0.70). Effect sizes were negative and not statistically different for effortful control (k&thinsp;=&thinsp;1; SMD&thinsp;=&thinsp;&minus;0.53, 95% CI&thinsp;=&thinsp;&minus;1.50, 0.45), inhibition (k&thinsp;=&thinsp;2; SMD&thinsp;=&thinsp;&minus;0.08, 95% CI&thinsp;=&thinsp;&minus;0.47, 0.31), working memory (k&thinsp;=&thinsp;1; SMD&thinsp;=&thinsp;0.00, 95% CI&thinsp;=&thinsp;&minus;0.45, 0.44), and planning and organisation (k&thinsp;=&thinsp;1; SMD&thinsp;=&thinsp;&minus;0.10, 95% CI&thinsp;=&thinsp;&minus;0.55, 0.34). No statistically significant heterogeneity was found for any of the syntheses of indirect measures of EF. Based on pre-post single-group designs, there was evidence for small to medium sized improvements in EF based on direct measures (cognitive flexibility, verbal working memory and visual working memory) and indirect measures (behavioural regulation, shifting, inhibition and meta-cognition). However, these results must be interpreted with caution due to high risk of bias.

**Authors&#039; Conclusions**
This review found limited and uncertain evidence for the effectiveness of interventions for improving executive functioning in children with FASD across 8 direct and 13 indirect measures of EF. The findings are limited by the small number of high-quality studies that could be synthesised by meta-analysis and the very small sample sizes for the included studies.
AU  - Betts,
AU  - J.
AU  - L.
AU  - Eggins,
AU  - E.
AU  - Chandler-Mather,
AU  - N.
AU  - Shelton,
AU  - D.
AU  - Till,
AU  - H.
AU  - Harnett,
AU  - P.
AU  - Dawe,
AU  - S.
DB  - Alerts 6_2022.enl
DO  - /10.1002/cl2.1258
L1  - internal-pdf://2334244930/Campbell Systematic Reviews - 2022 - Betts - I.pdf
PY  - 2022
T2  - Campbell Systematic Reviews
TI  - Interventions for improving executive functions in children with foetal alcohol spectrum disorder (FASD): A systematic review
ER  -
TY  - JOUR
AB  - **Purpose:** 
This study aimed to investigate the effect of exercise intervention, and analyze exercise intervention strategies for adolescent depression through a meta-analysis of RCTs. 

**Methods:** 
Accordance to PRISMA guidelines, PubMed, Medline, EBSCO, Web of Science, SPORTDiscus, PsycINFO, ProQuest, and CNKI were searched for eligible records. Peer-reviewed studies were included if they met the following criteria: population (mean age of 10-18 years), intervention (physical activity, sport, or exercise), and outcomes (depression, adherence, ITT, dropout, adverse events, follow-up report). The protocol of this systematic review was registered in PROSPERO (CRD42022321683). Effect sizes calculations and methodological quality of exercise intervention (TESTEX scale) were carried out. The certainty of evidence was assessed by GRADE framework. 

**Results:** 
Thirteen randomized controlled trials were eligible for this review, which comprised a total of 433 adolescents. Compared with the control treatment, the effect of exercise on adolescent depression was moderate (SMD = -0.65, 95%CI: -1.03 to -0.27, p &lt; 0.01). Heterogeneity was substantial (T &lt;sup&gt;2&lt;/sup&gt; = 0.30, I &lt;sup&gt;2&lt;/sup&gt; = 67%, p &lt; 0.01). The moderating effect analysis showed that exercise intervention characteristics (organization form, exercise frequency, exercise intensity, exercise type, and single exercise session duration) of included studies varied greatly revealing multiple factors that may impact the antidepressant effect of exercise on adolescent depression (I &lt;sup&gt;2&lt;/sup&gt; &gt; 50%, p &lt; 0.05). Three studies show that the positive effect of exercise on reducing depression in adolescents remained 40 weeks after the intervention. Moreover, owing to the included studies contained methodological limitations, the certainty of evidence was reduced to moderate level. 

**Conclusion:** 
This study shows that exercise intervention has a moderate and sustained positive effect on adolescent depression. Our results recommended that adolescents with depression undertake moderate to high intensity group mixed exercise for more than 12 weeks, 20 to 60 min/time, more than 3 times/week. Additionally, our study also shows that the antidepressant effects remained for a long time after the end of exercise interventions. However, following the GRADE framework, we rated the certainty of evidence the primary meta-analysis as moderate evidence due to some limitations of included studies. Therefore, rigorous studies are still needed to verify the results. Systematic review registration: [https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=321683], identifier [CRD42022321683].
AN  - 36687827
AU  - Zhang,
AU  - C.
AU  - S.
AU  - Cheng,
AU  - L.
AU  - Chen,
AU  - X.
AU  - Wang,
AU  - Y.
AU  - Wei,
AU  - S.
AU  - Sun,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyg.2022.974382
L1  - internal-pdf://0184485429/fpsyg-13-974382.cleaned.pdf
PY  - 2022
SP  - 974382
T2  - Frontiers in Psychology
TI  - The strategies of exercise intervention for adolescent depression: A meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36687827
VL  - 13
ER  -
TY  - JOUR
AB  - **Background**
A growing number of studies have suggested that transcranial magnetic stimulation (TMS) may represent a novel technique with both investigative and therapeutic potential for autism spectrum disorder (ASD). However, a full spectrum of the adverse effects (AEs) of TMS used in ASD has not been specifically and systematically evaluated. 

**Objective**
This systematic review and meta-analysis was to assess the prevalence of AEs related to TMS in ASD and to further explore the potentially related factors on the AEs. Methods: A systematic literature research of articles published before 31 December 2020 was conducted in the databases of PubMed, Embase, Cochrane Library, Ovid, PsycINFO, Chinese National Knowledge Infrastructure (CNKI), Chongqing VIP, and WANFANG DATA. AEs reported in the studies were carefully examined and synthesized to understand the safety and tolerability of TMS among ASD. Then, subgroup and sensitivity analyses were performed to examine the potentially related factors on the AEs. PROSPERO registration number: CRD42021239827. 

**Results**
Eleven studies were included in the meta-analysis. The pooled prevalence with 95% confidence interval (CI) of AEs was calculated (overall AEs: 25%, 95% CI 18-33%; headache: 10%, 95% CI 3-19%; facial discomfort: 15%, 95% CI 4-29%; irritability 21%, 95% CI 8-37%; pain at the application site: 6%, 95% CI 0-19%; headedness or dizziness: 8%, 95% CI 0-23%). All reported AEs were mild and transient with relatively few serious AEs and can be resolved after having a rest or medication. In addition, the following variables showed no significant change in overall prevalence of AEs: the purpose of using TMS, mean age of participants, whether the stimulation site was dorsolateral pre-frontal cortex (DLPFC), intensity of TMS, and the number of stimulation sessions. 

**Conclusion**
The overall prevalence of reported AEs of TMS among ASD was 25%. No identified ASD-specific risk factors for TMS-induced AEs were found. Further studies are needed to clarify the variation in the prevalence.
AN  - WOS:000807155700001
AU  - Huashuang,
AU  - Z.
AU  - Yang,
AU  - L.
AU  - Chensheng,
AU  - H.
AU  - Jing,
AU  - X.
AU  - Bo,
AU  - C.
AU  - Dongming,
AU  - Z.
AU  - Kangfu,
AU  - L.
AU  - Shi-Bin,
AU  - W.
DB  - Alerts 6_2022.enl
DO  - 10.3389/fpsyt.2022.875591
L1  - internal-pdf://3312043808/fpsyt-13-875591.cleaned.pdf
PY  - 2022
SP  - 12
T2  - Frontiers in Psychiatry
TI  - Prevalence of Adverse Effects Associated With Transcranial Magnetic Stimulation for Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000807155700001
VL  - 13
ER  -
TY  - JOUR
AB  - In this systematic review, we examined the use of technology-based interventions to teach science, technology, engineering, and mathematics (STEM) skills to K-12 autistic students. Twenty peer-reviewed articles with 59 autistic participants, ages 5-21 and published between 2012 and 2021 were included. Studies used a variety of technology-based interventions, including video-based intervention (n = 10), virtual manipulatives (n = 7), computer-assisted instruction (n = 2), and e-texts (n = 1). Sixteen studies focused on mathematics skills, three studies on science skills, and one on both. Using the Reichow et al. (2008) evaluative method, we determined that technology-based interventions for teaching STEM skills to K-12 autistic students can be classified as an established evidence-based practice. Yet, readers should use caution when interpreting the findings, as a variety of technology-based intervention were included in this study.
AN  - WOS:000902993000001
AU  - Yakubova,
AU  - G.
AU  - Chen,
AU  - B.
AU  - B.
AU  - Defayette,
AU  - M.
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1007/s40489-022-00351-5
L1  - internal-pdf://3478847905/Yakubova-The Use of Technology-Based Intervent.pdf
PY  - 2022
SP  - 20
T2  - Review Journal of Autism and Developmental Disorders
TI  - The Use of Technology-Based Interventions in Teaching STEM Skills to Autistic Students in K-12 Settings: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000902993000001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-022-00351-5.pdf
ER  -
TY  - JOUR
AB  - ABSTRACT There is a pressing need for effective interventions targeting mental disorders for service-involved youth across child welfare, correctional and mental health residential settings. Identifying effective common practice elements (CPEs) is a promising direction toward developing effective, flexible, and feasible therapeutic interventions. The aims of this study were: 1) to identify CPEs in treatment programs for adolescents with internalizing and/or externalizing disorders across residential settings, 2) to identify which CPEs are present in effective versus all trials, and 3) to estimate whether the presence of each CPE is associated with treatment effects. A systematic search identified 24 trials of programs targeting adolescent internalizing and/or externalizing symptoms, yielding 148 effect estimates. Discrete practices were coded into CPE categories across effective trials and the full sample. Eleven CPEs were identified and employed as moderators in three-level meta-analyses. We found large significant moderator effects of two elements on externalizing symptoms: Emotion recognition and differentiation, and Psychoeducation. No CPE was significantly related to effects on internalizing outcomes. The results illustrate the difference between CPE frequency and association with effect, favoring a combination of the two approaches. Emotion recognition and differentiation, and Psychoeducation should be prioritized in novel interventions targeting adolescent externalizing behavior in residential settings. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-93374-001
AU  - Kvamme,
AU  - L.
AU  - S.
AU  - Keles,
AU  - S.
AU  - Nes,
AU  - R.
AU  - B.
AU  - Vaskinn,
AU  - L.
AU  - Waaler,
AU  - P.
AU  - M.
AU  - Wentzel-Larsen,
AU  - T.
AU  - Kjobli,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/0886571X.2022.2111397
L1  - internal-pdf://3694100905/0886571X.2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Residential Treatment for Children &amp; Youth
TI  - Common practice elements in treatment programs for adolescents with externalizing and internalizing problems: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-93374-001
UR  - https://www.tandfonline.com/doi/full/10.1080/0886571X.2022.2111397
ER  -
TY  - JOUR
AB  - OBJECTIVE: Fatigue is common in adolescence and can be highly disabling if experienced persistently, with adverse psychosocial outcomes. There is a need to better understand what nonpharmacological treatments are available for adolescents suffering with persistent fatigue. The current review systematically identified, synthesised, and evaluated the evidence regarding nonpharmacological interventions for fatigue in adolescents, focusing on evaluating effectiveness, describing intervention components, and mapping interventions onto the behaviour change technique taxonomy (BCTT). 

METHODS: CENTRAL, EMBASE, PsycINFO, PubMed, and Web of Science were systematically searched for articles including (1) adolescents aged 10-19 years old, (2) fatigue as a primary or secondary outcome, (3) nonpharmacological interventions, and (4) randomised controlled trials. Study screening, data extraction, quality assessment, and BCTT mapping were performed independently by two reviewers. Findings were presented as a narrative synthesis, with interventions ranked by promise. 

RESULTS: 5626 papers were identified and double-screened, resulting in the inclusion of 21 articles reporting 16 trials. Five interventions were classified as likely promising. Interventions often involved psychoeducation, cognitive behavioural therapy, and/or physical activity, incorporating various BCTT domains, most commonly shaping knowledge, repetition and substitution, and goals and planning. However, there did not seem to be any observable differences between fatigue-targeted and non-fatigue-targeted interventions. Overall study quality was mixed, particularly in relation to power and outcome measures. 

CONCLUSION: There are several promising nonpharmacological interventions for adolescent fatigue, although further work is needed to determine effectiveness. Future trials need to ensure design rigour, focusing on adequate powering, validated outcome measures, and adhering to best practice reporting guidelines.
AN  - 36327529
AU  - Higson-Sweeney,
AU  - N.
AU  - Mikkola,
AU  - A.
AU  - Smith,
AU  - L.
AU  - Shafique,
AU  - J.
AU  - Draper,
AU  - L.
AU  - Cooper,
AU  - K.
AU  - Dunn,
AU  - B.
AU  - D.
AU  - Loades,
AU  - M.
AU  - E.
DB  - Alerts 6_2022.enl
DO  - /10.1016/j.jpsychores.2022.111070
L1  - internal-pdf://0742573739/Higson_Sweeney_2022.pdf
PY  - 2022
SP  - 111070
T2  - Journal of Psychosomatic Research
TI  - Nonpharmacological interventions for treating fatigue in adolescents: A systematic review and narrative synthesis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36327529
VL  - 163
ER  -
TY  - JOUR
AB  - Public Health Significance Statement Early behavioral interventions for autism spectrum disorders in children treated in routine clinical care was found efficacious in reducing symptoms within the outcome domains adaptive behavior, cognition, communication, and socialization, with medium to large within-group effect sizes at post-treatment and follow-up. The outcome of effectiveness studies was similar to that of efficacy studies. Our findings suggest that clinicians and patients can be confident about the effectiveness of early behavioral interventions with already established efficacy when delivered in routine clinical care. As treatment effects are not lost when evidence-based treatment programs are transported from research clinics to routine clinical care, further implementation of evidence-based interventions is needed in routine clinical care for children with autism disorders. The current paper systematically reviews and meta-analyses the effectiveness of early behavioral interventions (BI) for children with autism spectrum disorder (ASD) in routine clinical care. The effectiveness of BI, methodological study quality, and moderators of treatment outcome were examined and benchmarked with efficacy studies. The quality of the evidence was assessed with the Cochrane risk of bias tool. Twenty-nine studies were included, comprising 1,422 participants. Medium to large within-group effect sizes (g = 0.76-1.27) were found post-treatment for the outcome domains adaptive behavior, cognition, communication, and socialization, with large average effect size at post (g = 0.94) and at follow-up (g = 1.08). Comparison of effectiveness and efficacy studies showed that evidence-based early BI in routine clinical care yielded effects comparable to university research settings. The limitations include potential language and publication bias. The findings support evidence-based behavioral treatments delivered in routine clinical care as efficacious in reducing ASD symptoms. PROSPERO registration: ID CRD42020212833.
AN  - WOS:000835444100001
AU  - Wergeland,
AU  - G.
AU  - J.
AU  - H.
AU  - Posserud,
AU  - M.
AU  - B.
AU  - Fjermestad,
AU  - K.
AU  - Njardvik,
AU  - U.
AU  - Ost,
AU  - L.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1037/cps0000106
L1  - internal-pdf://1976930070/2022-87051-001.cleaned.pdf
PY  - 2022
SP  - 16
T2  - Clinical Psychology-Science and Practice
TI  - Early Behavioral Interventions for Children and Adolescents With Autism Spectrum Disorder in Routine Clinical Care: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000835444100001
ER  -
TY  - JOUR
AB  - Parents are the primary source of support for their children and can become principal interventionists for preventing and treating their child&#039;s challenging behavior. Yet, providing adequate and adapted training for culturally diverse families can be difficult due to the increase of international migration and the diversity of languages spoken worldwide. This systematic review and meta-analysis evaluated 13 studies that implemented training for caregivers with limited proficiency in the majority language. Overall, the results suggested a moderate-small treatment effects on positive and negative parenting practices. The results also indicated moderate-small treatment effects on challenging behaviors exhibited by both individuals with developmental disabilities and typically developmental. Findings are discussed in terms of strategies used and recommendations for future research and practice. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AU  - Vargas
AU  - Londono,
AU  - F.
AU  - Lim,
AU  - N.
AU  - Barnett,
AU  - M.
AU  - R.
AU  - Hampton,
AU  - L.
AU  - H.
AU  - Falcomata,
AU  - T.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-022-05564-5
L1  - internal-pdf://4039131389/Training culturally diverse caregivers to-2022.pdf
PY  - 2022
T2  - Journal of Autism and Developmental Disorders
TI  - Training culturally diverse caregivers to decrease their child&#039;s challenging behaviors: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-58601-001
UR  - https://link.springer.com/article/10.1007/s10803-022-05564-5
UR  - https://link.springer.com/content/pdf/10.1007/s10803-022-05564-5.pdf
ER  -
TY  - JOUR
AB  - Anxiety and depression are listed as common side effects for medications licensed for treating ADHD in children and adolescents. This meta-analytic review of randomised controlled trials aimed to explore the effect of medications on symptoms of anxiety and depression in children and adolescents with ADHD. A meta-analytic review of ADHD drug trials in children and adolescents was conducted. Random effects meta-analyses were conducted on anxiety and depression outcomes measured by validated psychological scales or side effect rating scales. Only 11% of eligible trials in this review reported anxiety and/or depression as an outcome or side effect, limiting the conclusions of the meta-analyses. Relative to placebo control, no significant effect of medication was found for symptoms of anxiety or depression in randomised controlled trials of ADHD medication in children and adolescents. This review highlights the systemic lack of mental health outcome reporting in child and adolescent ADHD drug trials. The importance of widespread implementation of standardised measurement of mental health outcomes in future trials is discussed.
AN  - 35616714
AU  - Bryant,
AU  - A.
AU  - Schlesinger,
AU  - H.
AU  - Sideri,
AU  - A.
AU  - Holmes,
AU  - J.
AU  - Buitelaar,
AU  - J.
AU  - Meiser-Stedman,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-022-02004-8
L1  - internal-pdf://3783725769/A meta-analytic review of the impact of A-2022.pdf
PY  - 2022
SP  - 26
T2  - European Child &amp; Adolescent Psychiatry
TI  - A meta-analytic review of the impact of ADHD medications on anxiety and depression in children and adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35616714
UR  - https://link.springer.com/content/pdf/10.1007/s00787-022-02004-8.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - **Background:**
Factors affecting the effectiveness of electroencephalogram-based neurofeedback (EEG-NF) against the core symptoms of attention-deficit/hyperactivity disorder (ADHD) remain unclear.

**Methods:**
We searched the PubMed, Embase, Web of Science, ClinicalKey, Cochrane CENTRAL, ScienceDirect, and databases from inception to August 2022 for randomized controlled trials (RCTs) on patients with ADHD involving outcome assessments of improvements on behavioural rating scales of inattention, hyperactivity/impulsivity, and global symptoms. Comparators included nonactive (e.g., wait list/treatment as usual) and active (e.g., cognitive training) controls.

**Results:**
Our analyses included 21 RCTs comprising 1261 participants. Our results demonstrated significantly better improvement in symptoms of inattention, hyperactivity/impulsivity and global symptoms of ADHD associated with EEG-NF than comparators from both proximal (p = 0.01, p = 0.02 and p = 0.01, respectively; e.g., parents) and distal (p = 0.01, p &lt; 0.05 and p = 0.01; e.g., teachers) raters. Meta-regression revealed a positive association between therapeutic effects of EEG-NF and intelligence quotient (IQ) from observations of the most proximal raters. Subgroup analysis for studies combining 2 EEG-NF protocols showed better therapeutic effectiveness against symptoms of ADHD than those using a single NF protocol, whereas subgroup analysis adopting a double-blind design failed to demonstrate superiority of EEG-NF to sham control. Moreover, therapeutic effectiveness of EEG-NF was significantly better when wait list/treatment as usual comparators were used compared with sham/placebo EEG-NF controls on subgroup analysis.Limitations:Our findings are limited by the lack of a double-blind design in most of the studies included in our analyses.

**Conclusion:**
Our results support the effectiveness of EEG-NF for improving inattention, hyperactivity/impulsivity, and global symptoms in patients with ADHD. The high risk of detection and performance bias warrants further study.
AN  - WOS:000900410500001
AU  - Chung,
AU  - W.
AU  - L.
AU  - Yeh,
AU  - P.
AU  - Y.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Liu,
AU  - C.
AU  - Fan,
AU  - H.
AU  - Y.
AU  - Tzang,
AU  - R.
AU  - F.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Chiu,
AU  - H.
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1503/jpn.220125
L1  - internal-pdf://1202347097/Chung-2022-Factors influencing therapeutic eff.pdf
PY  - 2022
SP  - E435-E446
T2  - Journal of Psychiatry &amp; Neuroscience
TI  - Factors influencing therapeutic effectiveness of electroencephalogram-based neurofeedback against core symptoms of ADHD: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000900410500001
UR  - https://www.jpn.ca/content/jpn/47/6/E435.full.pdf
VL  - 47
ER  -
TY  - JOUR
AB  - **Introduction**
Second-generation antipsychotics are associated with significant weight gain. The aim of this systematic review and meta-analysis was to determine the efficacy and safety of metformin for the treatment of weight gain in children and young adults treated with second-generation antipsychotics.

**Methods**
We followed PRISMA guidelines to evaluated studies published before March 2020 in Medline, Google Scholar, PubMed, Cochrane library database, annual scientific sessions of the American Psychiatric Association, American Academy of Child and Adolescent, Psychiatry, and American Society of Clinical Psychopharmacology. Studies included compared metformin with the placebo for management of weight gain in children and adolescents taking atypical antipsychotics. Non-randomized studies, animal experiment studies, editorials, and review studies were excluded. Multiple parameters, including change in anthropometric-biochemical parameters, drug discontinuation rate, and side effects among the groups were assessed. The random-effects method was used for meta-analysis.

**Results**
Four studies with were included in the final analysis (213 patients; metformin: 106; control: 107). After pooled analysis, 12-16 weeks of metformin therapy was associated with a significant reduction in weight [(mean difference (MD): -4.53 lbs, confidence interval (CI): -6.19 to -2.87, p-value &lt; 0.001)], and BMI z score [MD, -0.09, CI: -0.16, -0.03, p-value: 0.004] compared to control. Metformin was also associated with a significant reduction in insulin resistance [MD: -1.38, CI: -2.26 to -0.51, p-value: 0.002]. There were higher odds of nausea-vomiting [OR: 4.07, CI: 1.32-12.54, p-value: 0.02] and diarrhea [OR: 2.93, CI: 1.50-5.71, p-value: 0.002] in the metformin group. However, there was no difference in drug discontinuation rate [OR: 1.45, CI: 0.41-5.06, p-value: 0.56].

**Conclusion**
Metformin may prove beneficial in the treatment of weight gain in children treated with second-generation antipsychotics. The pooled treatment effect showed a significant reduction in BMI Z-score and weight in just 12-16 weeks. The limitations include small sample size, variation in metformin dose, and duration of treatment. This meta-analysis should be interpreted as promising, and further larger studies are warranted before drawing a conclusion.
AD  - Mansuri, Zeeshan. Department of Psychiatry, Boston Children&#039;s Hospital and Harvard Medical School, Boston, MA, United States.Makani, Ramkrishna. Department of Psychiatry, AtlantiCare Health System, Egg Harbor Township, NJ, United States.Trivedi, Chintan. Department of Psychiatry, Texas Tech University Health Sciences Center at Permian Basin, Odessa, TX, United States.Adnan, Mahwish. Department of Psychiatry, Texas Tech University Health Sciences Center at Permian Basin, Odessa, TX, United States.Vadukapuram, Ramu. The University of Texas Rio Grande Valley, Harlingen, TX, United States.Rafael, John. MS4, Texas Tech University Health Sciences Center at Permian Basin, Odessa, TX, United States.Lodhi, Ashutosh. Providence Medical Group, Beaverton, OR, United States.Reddy, Abhishek. Department of Psychiatry, Virginia Tech Carilion School of Medicine, Roanoke, VA, United States.
AN  - 36458118
AU  - Mansuri,
AU  - Z.
AU  - Makani,
AU  - R.
AU  - Trivedi,
AU  - C.
AU  - Adnan,
AU  - M.
AU  - Vadukapuram,
AU  - R.
AU  - Rafael,
AU  - J.
AU  - Lodhi,
AU  - A.
AU  - Reddy,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyt.2022.933570
DP  - Ovid Technologies
J2  - Front Psychiatr
L1  - internal-pdf://3859109295/fpsyt-13-933570.cleaned.pdf
LA  - English
M3  - Systematic Review
N1  - Mansuri, ZeeshanMakani, RamkrishnaTrivedi, ChintanAdnan, MahwishVadukapuram, RamuRafael, JohnLodhi, AshutoshReddy, Abhishek
PY  - 2022
SP  - 933570
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - The role of metformin in treatment of weight gain associated with atypical antipsychotic treatment in children and adolescents: A systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36458118
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36458118&amp;id=doi:10.3389%2Ffpsyt.2022.933570&amp;issn=1664-0640&amp;isbn=&amp;volume=13&amp;issue=&amp;spage=933570&amp;pages=933570&amp;date=2022&amp;title=Frontiers+in+psychiatry+Frontiers+Research+Foundation&amp;atitle=The+role+of+metformin+in+treatment+of+weight+gain+associated+with+atypical+antipsychotic+treatment+in+children+and+adolescents%3A+A+systematic+review+and+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Mansuri&amp;pid=%3Cauthor%3EMansuri+Z%3C%2Fauthor%3E%3CAN%3E36458118%3C%2FAN%3E%3CDT%3ESystematic+Review%3C%2FDT%3E
VL  - 13
ER  -
TY  - JOUR
AB  - Challenging behavior tends to increase in levels during adolescence for individuals with developmental disabilities (DD). If not addressed, this can lead to negative post-school outcomes for adolescents with DD. The purposes of this meta-analysis were to examine the effects of behavioral intervention in reducing challenging behaviors of adolescents with DD and to identify variables that could potentially moderate these effects. This meta-analysis included thirty single-case design studies that met standards for methodological rigor and experimental control. Overall, behavioral interventions were found to yield moderate effects for adolescents with DD (overall Tau-U = 0.68, SD = 0.04, [0.62, 0.73]) across settings and types of challenging behaviors. With regards to participant and setting characteristics, verbal ability and classroom setting were found to moderate the effects of the intervention outcomes with statistical significance. No other variables produced similar findings. Furthermore, statistically significant differences were found between interventions that included or did not include planned reinforcement as an intervention component. Several implications for research and practice are discussed. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-43481-001
AU  - David,
AU  - M.
AU  - Mason,
AU  - R.
AU  - Davis,
AU  - J.
AU  - Gregori,
AU  - E.
AU  - Lei,
AU  - Q.
AU  - Lory,
AU  - C.
AU  - Wang,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10882-022-09841-0
L1  - internal-pdf://2112268756/School-based interventions targeting chal-2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Journal of Developmental and Physical Disabilities
TI  - School-based interventions targeting challenging behavior of adolescents with developmental disabilities: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-43481-001
UR  - https://link.springer.com/content/pdf/10.1007/s10882-022-09841-0.pdf
ER  -
TY  - JOUR
AB  - **Background**
Mentoring, specifically peer mentoring, emerged in the child welfare setting in the early 2000s. Peer parent programs provide child welfare involved families a unique opportunity to connect with parents that have successfully navigated the child welfare system and who share similar lived experiences. No systematic review has been conducted to summarize findings associated with parental participation in peer parent programs and associated child welfare case outcomes. 

**Objective(s)**
This study systematically summarizes the effectiveness of peer parent programs in child welfare on case outcomes, specifically permanency, time-in-care, and re-entry post reunification. 

**Method(s)**
Four citations were identified for review from seven academic databases. A data template was utilized to extract the following information from each study: location, target of intervention, research design, setting of intervention, intervention description, peer parent criteria, inclusion and exclusion criteria for participants, sample size, statistical tests, outcomes assessed, and key findings. 

**Result(s)**
Several peer parent programs have been developed to support and empower child welfare involved families with the aim of improving case outcomes. All of the peer parent programs reviewed had a positive impact on reunification rates; that is, parents who participated in a peer mentor program were more likely to reunify with their child(ren) when compared to non-participants. Results regarding time-in-care and re-entry post reunification at 12 and 24 months were mixed. 

**Conclusion(s)**
Child welfare agencies should consider developing peer parent programs as they appear to be a promising intervention to support parents and increase positive child welfare outcomes. Copyright &copy; 2022 Elsevier Ltd
AN  - 2018434465
AU  - Saeteurn,
AU  - E.
AU  - R.
AU  - Wu,
AU  - Q.
AU  - Vasiliou,
AU  - N.
AU  - Mabingani,
AU  - D.
AU  - Krysik,
AU  - J.
DB  - Alerts 6_2022.enl
DO  - /10.1016/j.chiabu.2022.105682
L1  - internal-pdf://3263221519/1-s2.0-S0145213422002022-main.cleaned.pdf
PY  - 2022
T2  - Child Abuse and Neglect
TI  - Peer parent programs in child welfare: A systematic review
UR  - https://www.elsevier.com/locate/chiabuneg
UR  - https://www.sciencedirect.com/science/article/pii/S0145213422002022?via%3Dihub
VL  - 129 (no pagination)
ER  -
TY  - JOUR
AB  - Preventive postdivorce interventions aim to help children cope with divorce and promote their adjustment. Nevertheless, questions remain regarding the concrete outcomes of these interventions and the intervention characteristics that influence them. This meta-analysis of 30 studies analyzes the efficacy of postdivorce interventions on children&#039;s symptomatology, personal resources, and adaptation to divorce. Likewise, it explores whether the intervention impacts the putative mediators from the family context and whether the characteristics of the studies themselves also influence the results. Using a data set of N = 4344 individuals, 258 effect sizes were calculated. Random effects analyses evidenced the impact of the interventions on specific variables instead of on children&#039;s global adjustment. There were no significant effects on children&#039;s mental health outcomes, and none of these effects were qualified by the moderators that were examined. Preventive postdivorce interventions had significant effects, specifically on children&#039;s divorce adjustment and self-esteem. The study of the moderators found that the interventions were generally homogeneous, and only one of the 20 moderators examined had a significant effect. Based on children&#039;s age, the interventions had an impact on family functioning only when they involved younger children, but this result should be interpreted with caution due to the small sample of studies. This meta-analysis provides evidence of the relevance of postdivorce interventions to critical variables as well as information about the role of the intervention characteristics in the effects and makes suggestions for future research on divorce interventions that encompass both practical and empirical developments.
AN  - 36054156
AU  - Herrero,
AU  - M.
AU  - Roca,
AU  - P.
AU  - Cormenzana,
AU  - S.
AU  - Martinez-Pampliega,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/famp.12807
L1  - internal-pdf://4257726982/Herrero-2022-The efficacy of postdivorce inter.pdf
PY  - 2022
SP  - 29
T2  - Family Process
TI  - The efficacy of postdivorce intervention programs for children: A meta-analytical review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36054156
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/famp.12807?download=true
VL  - 29
ER  -
TY  - JOUR
AB  - Video-based intervention (VBI) is an evidence-based practice for teaching a wide array of skills to autistic children and young adults; however, a limited number of studies have examined the effectiveness of parent-implemented VBI when teaching children functional skills in a home setting. The purpose of this evidence-based systematic review was to synthesize and evaluate the evidence base for parent-implemented VBI to teach functional skills to autistic children in a home setting. Nine studies published between 2012 and 2021 met the inclusion criteria for this review. Seven of these studies met the design standards and had strong or adequate levels of evidence. The findings indicate that parent-implemented VBI meets the criteria to be classified as a probable evidence-based practice, but a great variability exists in the methods of parent training, levels of parental involvement, and skills taught.
AN  - WOS:000777354300001
AU  - Yakubova,
AU  - G.
AU  - Chen,
AU  - B.
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40489-022-00316-8
L1  - internal-pdf://1800563424/Parent-Implemented Video-Based Intervention to.pdf
PY  - 2022
SP  - 24
T2  - Review Journal of Autism and Developmental Disorders
TI  - Parent-Implemented Video-Based Intervention to Teach Autistic Children: an Evidence-Based Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000777354300001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-022-00316-8.pdf
ER  -
TY  - JOUR
AB  - Stepped care approaches have been developed to increase treatment accessibility for individuals with posttraumatic stress disorder (PTSD). However, despite guidelines recommending stepped care, it is currently unclear how the approach compares to other treatments for PTSD in terms of symptom reduction, cost, and client-rated acceptability. We conducted a systematic review and meta-analysis of randomized controlled and open trials evaluating stepped care prevention (i.e., targeting those with recent trauma exposure at risk of developing PTSD) and treatment approaches for adults and adolescents/children with PTSD. Eight prevention and four treatment studies were included. There was considerable variation in the sample types, stepped approaches, and control conditions. Most studies found no significant differences between stepped care (both prevention and treatment) and control (active and usual care) in terms of PTSD severity, loss of PTSD diagnosis, depression severity, and quality of life at the final follow-up. There was some evidence to suggest that stepped care was more cost-effective, and as acceptable or more acceptable compared to controls. Interpretations were tempered by high statistical heterogeneity, risk of bias, and lack of recommended evidence-based treatments. Stepped care can make PTSD treatment more accessible; however, more high-quality research is needed comparing stepped care to active controls. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-45877-001
AU  - Roberts,
AU  - L.
AU  - N.
AU  - Nixon,
AU  - R.
AU  - D.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.beth.2022.11.005
L1  - internal-pdf://1779128745/1-s2.0-S0005789422001411-main.cleaned.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Behavior Therapy
TI  - Systematic review and meta-analysis of stepped care psychological prevention and treatment approaches for posttraumatic stress disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc19&amp;AN=2023-45877-001
ER  -
TY  - JOUR
AB  - **Objectives**
The purpose of this review was to systematically search and critically analyse literature concerning the efficacy of gluten-free and/or casein-free diets in treating maladaptive behaviours in children with autism spectrum disorder.

**Methods**
Eleven randomized clinical trials retrieved from PubMed and Cochrane Library databases and hand search were reviewed and assessed for methodological quality using the Cochrane Collaboration&#039;s risk of bias tool.

**Results**
Samples were mostly small, and few studies yielded evidence of statistically significant behavioural outcomes attributable to dietary interventions.

**Conclusions**
The results of this review imply that the efficacy of gluten-free and/or casein-free diets for individuals with autism spectrum disorder remains unsubstantiated. Larger and better designed studies focused on specific outcomes, and which are not dependent on unblinded researcher or parent report, are needed to establish whether gluten-free and/or casein-free diets are effective for children with autism spectrum disorder or any subgroup of such children.Systematic Review RegistrationPROSPERO CRD42020142407. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-81367-001
AU  - Batarseh,
AU  - H.
AU  - AbuMweis,
AU  - S.
AU  - Almakanin,
AU  - H.
AU  - A.
AU  - Anderson,
AU  - C.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s41252-022-00268-4
L1  - internal-pdf://1747434094/Batarseh-2022-Gluten-free and casein-free diet.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Advances in Neurodevelopmental Disorders
TI  - Gluten-free and casein-free diet for children with autism spectrum disorder: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-81367-001
UR  - https://link.springer.com/article/10.1007/s41252-022-00268-4
UR  - https://link.springer.com/content/pdf/10.1007/s41252-022-00268-4.pdf
ER  -
TY  - JOUR
AB  - Given the high prevalence of cyberbullying and its negative physical and psychological effects on the development of adolescents, numerous studies have attempted its reduction by developing anti-cyberbullying interventions. In the present study, we investigated the effectiveness of parent-related programs in reducing the frequency of cyberbullying perpetration and victimization among adolescents. 

A thorough search was carried out on seven electronic databases: EBSCO, ERIC, PubMed, PsycINFO, Scopus, Web of Science, and ProQuest Dissertations and Theses. Only quantitative studies that reported the effectiveness of parent-related programs in reducing the frequency of cyberbullying perpetration or victimization were included in the review. Eleven studies were finalized, and meta-analyses were performed using a random effect model on RevMan v5.4 software developed by Cochrane. 

Findings reveal that existing parent-related programs have very small effect sizes on cyberbullying perpetration (standardized mean differences [SMDs] = -0.17, 95% confidence interval [CI] [-0.26, -0.09]) and victimization (SMD = -0.17, 95% CI [-0.24, -0.10]). The modes of parental involvement and intervention do not moderate the program effectiveness, but those with shorter durations are more effective than longer ones in reducing the frequency of cyberbullying victimization. Furthermore, findings indicate that interventions with a theoretical foundation are more effective than those without one. 

This review provides evidence to improve anti-cyberbullying interventions by effectively enabling parent involvement, as well as increasing parenting skills, parent-child interactions, and communication. Given the limited effectiveness of parent-related interventions, future research is needed to identify key moderators to improve such programs or to develop school-family patterns to reduce cyberbullying.
AD  - Wang, Lin. Fudan University, Shanghai, China.Jiang, Shan. Zhejiang University, Hangzhou, China.
AN  - 36458864
AU  - Wang,
AU  - L.
AU  - Jiang,
AU  - S.
DA  - Dec 02
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/15248380221137065
DP  - Ovid Technologies
J2  - Trauma Violence Abuse Rev J
L1  - internal-pdf://0355883415/15248380221137065.cleaned.pdf
LA  - English
M3  - Review
N1  - Wang, LinJiang, Shan
PY  - 2022
SP  - 15248380221137065
T2  - Trauma Violence &amp; Abuse
TI  - Effectiveness of Parent-Related Interventions on Cyberbullying Among Adolescents: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36458864
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36458864&amp;id=doi:10.1177%2F15248380221137065&amp;issn=1524-8380&amp;isbn=&amp;volume=&amp;issue=&amp;spage=15248380221137065&amp;pages=15248380221137065&amp;date=2022&amp;title=Trauma+Violence+%26+Abuse&amp;atitle=Effectiveness+of+Parent-Related+Interventions+on+Cyberbullying+Among+Adolescents%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Wang&amp;pid=%3Cauthor%3EWang+L%3C%2Fauthor%3E%3CAN%3E36458864%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - Background: Panic disorder is a common and disabling psychiatric condition marked by sudden onset of physiological sensations that are appraised as dangerous. A number of studies and reviews have examined the efficacy of psychosocial treatments for PD; however, there is a lack of overarching reports that discuss the strength of evidence for the different psychosocial treatments for PD. This umbrella review provides an overview of systematic reviews and meta-analyses on psychosocial treatments for PD. Method(s): A systematic search and review of the literature was conducted according to PRISMA guidelines. Result(s): A total of 38 reviews (31 meta-analyses and 7 systematic reviews) were included in the umbrella review. Most of the 38 reviews were focused on the use of CBT, both in-person and internet-based, to treat PD among adults, generally finding it to be an efficacious treatment compared to control conditions. A limited number of the 38 reviews included other age ranges or examined other forms of psychosocial treatments. The methodological quality of most included reviews was rated as critically low according to the AMSTAR-2 rating system. Conclusion(s): Future reviews should focus on improving their methodological quality. Although the included reviews supported CBT as an efficacious treatment for reducing panic symptoms among adults, future research could focus on how CBT compares to other psychosocial treatments and the efficacy of CBT for PD among other populations (e.g., children and adolescents) and among diverse cultural groups. Copyright &copy; 2022 Elsevier Ltd
AN  - 2016507785
AU  - Rabasco,
AU  - A.
AU  - McKay,
AU  - D.
AU  - Smits,
AU  - J.
AU  - A.
AU  - Powers,
AU  - M.
AU  - B.
AU  - Meuret,
AU  - A.
AU  - E.
AU  - McGrath,
AU  - P.
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.janxdis.2022.102528
L1  - internal-pdf://2296227295/Psychosocial treatment for panic disorder-2022.pdf
PY  - 2022
T2  - Journal of Anxiety Disorders
TI  - Psychosocial treatment for panic disorder: An umbrella review of systematic reviews and meta-analyses
UR  - https://www.elsevier.com/inca/publications/store/8/0/1
VL  - 86 (no pagination)
ER  -
TY  - JOUR
AB  - **Background:** 
The psychological treatment of comorbid post-traumatic stress disorder (PTSD) and substance use disorder (SUD) is clinically challenging, and outcomes are often poor. 

**Objective:** 
This paper describes a systematic review and meta-analysis which sought to establish the current efficacy for a number of established psychological approaches for adults and adolescents, in comparison to interventions for SUD alone, or other active approaches, following a pre-registered protocol. 

**Method:** 
This review followed PRISMA and Cochrane Collaboration guidelines. Data extraction and risk of bias judgements using Cochrane criteria were undertaken by all authors. Primary outcomes were PTSD severity and substance use post-treatment. The quality of findings was assessed using GRADE. Following a comprehensive search, conducted to 13 September 2021, 27 studies were included. 

**Results:** 
We found a relatively high level of dropout across studies. In our main comparisons, we found no benefits for present-focused treatment approaches aimed at improving coping skills beyond those for SUD-only interventions. We found modest benefits for trauma-focused intervention plus SUD intervention post-treatment for PTSD (standardized mean difference (SMD) = -0.36, 95% confidence interval (CI) -0.64, -0.08), and at 6-13 months for PTSD (SMD = -0.48, 95% CI -0.81, -0.15) and alcohol use (SMD = -0.23, 95% CI -0.44, -0.02). There were no benefits for cognitive restructuring interventions as a group, but we found a modest effect for integrated cognitive behavioural therapy (ICBT) for PTSD post-treatment (SMD = -0.33, 95% CI -0.62, -0.04). There was evidence of some benefit for trauma-focused intervention over present-focused intervention for PTSD from a single study and for reduction in dropout for incentivized attendance for trauma-focused intervention from another single study. Most findings were of very low quality. 

**Conclusion:** 
There is evidence that trauma-focused therapy and ICBT can improve PTSD for some individuals, but many patients do not fully engage with treatment and average treatment effects are modest. HIGHLIGHTS: For PTSD, evidence was strongest for trauma-focused CBT-based approaches, but effects were modest. There was little evidence of any added benefit on substance use, beyond that of standard addiction treatments, for any included intervention.Dropout from treatment was high.
AN  - 35558682
AU  - Roberts,
AU  - N.
AU  - P.
AU  - Lotzin,
AU  - A.
AU  - Schafer,
AU  - I.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/20008198.2022.2041831
L1  - internal-pdf://2018062357/A systematic review and meta-analysis of-2022.pdf
PY  - 2022
SP  - 2041831
T2  - European Journal of Psychotraumatology
TI  - A systematic review and meta-analysis of psychological interventions for comorbid post-traumatic stress disorder and substance use disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35558682
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9090345/pdf/ZEPT_13_2041831.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - **Background:** 
Suicide becomes a widespread public health concern. Cognitive-behavioral therapy (CBT) is used to correct negative thoughts and behaviors of patients at risk of suicide. The aim of this research is to summarize and evaluate the existing evidence to explore the impact of CBT on suicide. 

**Method(s):**
We conducted a systematic searched in PubMed, Web of Science, Cochrane database from the first available year to March 2021. The methodological quality was evaluated by AMSTAR-2 tool, and the evidence quality was evaluated by GRADE classification. We summarized all the comparative effects of CBT on suicide, and used forest plots to describe the impact of CBT on suicide related outcomes included suicidal ideation, suicide attempts. The random effects model was used to summarize data. 

**Result(s):** 
Nine systematic reviews and meta-analysis were included. Most of the systematic reviews and meta-analysis were of medium methodological and evidence quality. The impact of CBT on suicide outcomes could be divided into the following two categories: CBT reduced levels of suicidal ideation (SMD -0.28, 95 % CI -0.36 to -0.21), CBT relieved suicide attempts (RR 0.77, 95 % CI 0.69 to 0.87). 

**Conclusion(s):** 
Based on the current evidence, CBT could relieve suicide, including suicide ideation, suicide attempts. CBT is scalable and cost-effective. It is helpful for health professionals to formulate personalized CBT programs, promote clinical and community applications and integrate them into comprehensive suicide interventions and prevention strategies. Copyright &copy; 2022
AN  - 2019980857
AU  - Wu,
AU  - H.
AU  - Lu,
AU  - L.
AU  - Qian,
AU  - Y.
AU  - Jin,
AU  - X.
AU  - H.
AU  - Yu,
AU  - H.
AU  - R.
AU  - Du,
AU  - L.
AU  - Fu,
AU  - X.
AU  - L.
AU  - Zhu,
AU  - B.
AU  - Chen,
AU  - H.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2022.08.067
L1  - internal-pdf://1074866139/1-s2.0-S0165032722009235-main.cleaned (1).pdf
PY  - 2022
SP  - 142-148
T2  - Journal of Affective Disorders
TI  - The significance of cognitive-behavioral therapy on suicide: An umbrella review of systematic reviews and meta-analysis
UR  - https://www.elsevier.com/locate/jad
VL  - 317
ER  -
TY  - JOUR
AB  - Research has demonstrated that regular school attendance is necessary for acceptable academic performance and the development of desirable social skills and behaviors. One in seven students in the United States struggles with chronic absenteeism, and 36 states use accountability metrics that are designed to assess attendance rates as part of school performance profiles. The current meta-analysis examined the effects of interventions and programs on student attendance outcomes in pre-K-12 public schools. Data were taken from 22 random and nonrandom controlled intervention studies published from 2000 to 2018. Between-group (weighted g = 0.25; 95% confidence interval [CI], 0.14-0.36) and within-group (weighted g = 1.04; 95% CI, 0.32-1.76) research designs resulted in small effects on attendance outcomes. Interventions were coded across three categories: behavioral interventions, family-school partnerships, and academic interventions. All three intervention areas resulted in small effects (weighted g = 0.09-0.26). The confidence interval for family-school partnerships was the only one that included 0, which suggests the possibility of a zero effect for that variable. Results suggest that most practices implemented to improve student attendance are either understudied, lead to small effects, or both. Implications for practice and future research regarding attendance interventions are discussed. Impact Statement: The current meta-analysis examined attendance interventions published from 2000 to 2018 and found 22 random and nonrandom controlled intervention studies across behavioral interventions, family-school partnerships, and academic interventions. Results demonstrated small effects for all three interventions, suggesting that most practices to improve student attendance are either understudied, lead to small effects, or both. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-26901-010
AU  - Eklund,
AU  - K.
AU  - Burns,
AU  - M.
AU  - Oyen,
AU  - K.
AU  - DeMarchena,
AU  - S.
AU  - McCollom,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/2372966X.2020.1789436
L1  - internal-pdf://1764292282/Addressing chronic absenteeism in schools-2022.pdf
PY  - 2022
SP  - 95-111
T2  - School Psychology Review
TI  - Addressing chronic absenteeism in schools: A meta-analysis of evidence-based interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-26901-010
UR  - https://www.tandfonline.com/doi/full/10.1080/2372966X.2020.1789436
VL  - 51
ER  -
TY  - JOUR
AB  - Early acknowledgment of developmental difficulties in young children strengthens both preventive and therapeutic approaches. Despite their feasibility, early intervention services are limited in Low-and-Middle-Income (LAMI) countries compared to high income countries. The aim of this study was to examine the evidence for early childhood intervention programs for developmental difficulties in children below five years in LAMI countries through a systematic review and meta-analysis. In this background, original studies published in peer-reviewed journals from 2010 to 2019 with a focus on developmental difficulties including delays and deviances; randomized research design with a clear description of the intervention and measurable outcomes, and conducted in LAMI countries were considered for the systematic review. Electronic databases, including ProQuest, PubMed, Ovid, EBSCOhost, and Google Scholar, were searched using a combination of specific keywords. PRISMA guidelines were followed to include the studies. Each of the selected study was assessed for quality before applying appropriate statistics to synthesize the data. Fourteen publications were identified from 2697 publications for the systematic review, out of which four were found compatible for a meta-analysis. The studies reviewed were conducted in Bangladesh, India, Pakistan, Uganda, Vietnam, and Zambia. A meta-analysis of four studies provided considerable evidence for the effects of early developmental intervention. This systematic review provides an evidence for early childhood intervention programs in LAMI countries. Implications of these findings for the early childhood programs are discussed in this article. (PsycInfo Database Record (c) 2024 APA, all rights reserved)
AN  - 2022-43976-001
AU  - Kumar,
AU  - Sapna
AU  - V.
AU  - Narayan,
AU  - Shweta
AU  - Malo,
AU  - Palash
AU  - Kumar
AU  - Bhaskarapillai,
AU  - Binukumar
AU  - Thippeswamy,
AU  - Harish
AU  - Desai,
AU  - Geetha
AU  - Kishore,
AU  - M.
DB  - Juli 2024.enl
DO  - /10.1016/j.ajp.2022.103026
L1  - internal-pdf://0959986271/1-s2.0-S1876201822000247-main.cleaned.pdf
PY  - 2022
SP  - 1-10
T2  - Asian Journal of Psychiatry
TI  - A systematic review and meta-analysis of early childhood intervention programs for developmental difficulties in low-and-middle-income countries
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc23&amp;DO=10.1016%2fj.ajp.2022.103026
VL  - 70
ER  -
TY  - JOUR
AB  - **Bakgrund och syfte**
Barn i Sverige har god h&auml;lsa i ett globalt perspektiv, men &ouml;ver tid har denpsykiska h&auml;lsan f&ouml;rs&auml;mrats. En dålig psykisk h&auml;lsa kan påverka barnsskolprestationer negativt och ofullst&auml;ndiga betyg från årskurs nio &ouml;kar risken f&ouml;rframtida psykosociala problem. Det &auml;r d&auml;rf&ouml;r angel&auml;get med insatser som kanfr&auml;mja psykisk h&auml;lsa, i denna rapport definierad som psykiskt v&auml;lbefinnande.

I det h&auml;r projektet utv&auml;rderade vi olika typer av program och programgruppersom inriktas på att fr&auml;mja psykiskt v&auml;lbefinnande. Sådana program syftar till attst&auml;rka friskfaktorer till skillnad från f&ouml;rebyggande program som syftar till attminska riskfaktorer f&ouml;r psykisk oh&auml;lsa. Program f&ouml;r att f&ouml;rb&auml;ttra levnadsvanoringick inte.

Vi inkluderade program som f&ouml;rmedlades till barnet sj&auml;lvt i f&ouml;rskolan ellerskolan, till f&ouml;r&auml;ldrarna eller hela familjen. Studier med individer upp till 18 årvar i fokus. Vi utv&auml;rderade effekterna dels som barnens upplevda psykiskav&auml;lbefinnande, dels som f&ouml;rmågor som kan fr&auml;mja psykiskt v&auml;lbefinnande, tillexempel social kompetens och resiliens. F&ouml;r att få en uppfattning omprogrammens fr&auml;mjande effekter accepterade vi resultat som m&auml;ttes i anslutningtill att studien avslutades eller senare.

Vi avgr&auml;nsade rapporten till program på universell nivå. Det inneb&auml;r att def&ouml;rmedlas brett, till exempel till hela skolor eller geografiska områden, utan attman valt ut specifika grupper eller individer. Vi inkluderade &auml;ven program somhade getts till hela skolor i socioekonomiskt utsatta områden. Ibland betraktasdetta som selektiva insatser eftersom deltagarna på gruppnivå kan t&auml;nkas ha enf&ouml;rh&ouml;jd risk f&ouml;r psykisk oh&auml;lsa.

Syftet med projektet var att kartl&auml;gga kunskapsl&auml;get f&ouml;r programmen. Rapporten&auml;r en del av ett regeringsuppdrag om psykisk h&auml;lsa bland barn och ungdomar(S2020/01043/FS), d&auml;r ytterligare två rapporter ingår (Program f&ouml;r att f&ouml;rebyggapsykisk oh&auml;lsa hos barn samt Program f&ouml;r att f&ouml;rebygga suicid och suicidf&ouml;rs&ouml;khos barn). I rapporten bed&ouml;mer vi programmens effekter på psykisktv&auml;lbefinnande, deltagarnas upplevelser av programmen samt dessaskostnadseffektivitet. Rapporten innehåller &auml;ven aspekter kring implementeringoch långtidseffekter samt etiska &ouml;verv&auml;ganden.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - https://www.sbu.se/sv/publikationer/SBU-utvarderar/framjande-av-psykiskt-valbefinnande-hos-barn-och-ungdomar/
L1  - internal-pdf://2354060135/framjande-av-psykiskt-valbefinnande-hos-barn-o.pdf
PY  - 2022
TI  - Fr&auml;mjande av psykiskt v&auml;lbefinnande hos barn och ungdomar
ER  -
TY  - JOUR
AB  - Despite increased numbers of children and adolescents seeking and receiving mental health treatment, rates of self-injurious thoughts and behaviors (SITBs) in youth are rising. In the hopes of aiding ongoing efforts to alleviate the burden of SITBs in this vulnerable population, the present study summarizes current knowledge on the efficacy of SITB interventions in children and adolescents. 

We conducted a meta-analysis of randomized controlled trials (RCTs) assessing treatment effects on SITBs in child and adolescent populations. A total of 112 articles comprising 558 effect sizes were included in analyses. 

Nearly all interventions produced nonsignificant reductions in SITBs. For binary SITB outcomes, a nonsignificant treatment effect was detected, with an RR of 1.06 (95% CIs [0.99, 1.14]). For continuous SITB outcomes, analyses also yielded a nonsignificant treatment effect (g = - 0.04 [- 0.12, 0.05]). These patterns were largely consistent across SITB outcomes, regardless of intervention type, treatment components, sample and study characteristics, and publication year. Our findings highlight opportunities for improving SITB intervention development and implementation in child and adolescent populations. 

The most efficacious interventions are likely to directly target the causes of SITBs; therefore, future research is needed to identify the causal processes underlying the onset and maintenance of SITBs in youth.
AN  - 35853962
AU  - Harris,
AU  - L.
AU  - M.
AU  - Huang,
AU  - X.
AU  - Funsch,
AU  - K.
AU  - M.
AU  - Fox,
AU  - K.
AU  - R.
AU  - Ribeiro,
AU  - J.
AU  - D.
DB  - Alerts 6_2022.enl
DO  - /10.1038/s41598-022-16567-8
L1  - internal-pdf://0735823007/Harris-2022-Efficacy of interventions for suic.pdf
PY  - 2022
SP  - 12313
T2  - Scientific Reports
TI  - Efficacy of interventions for suicide and self-injury in children and adolescents: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35853962
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9296501/pdf/41598_2022_Article_16567.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - BACKGROUND: Depression and anxiety are major public health concerns among adolescents. Computerized cognitive behavioral therapy (cCBT) has emerged as a potential intervention, but its efficacy in adolescents remains unestablished. 

OBJECTIVE: This review aimed to systematically review and meta-analyze findings on the efficacy of cCBT for the treatment of adolescent depression and anxiety. 

METHODS: Embase, PsycINFO, and Ovid MEDLINE were systematically searched for randomized controlled trials in English, which investigated the efficacy of cCBT for reducing self-reported depression or anxiety in adolescents aged 11 to 19 years. Titles, abstracts, and full texts were screened for eligibility by 2 independent researchers (TB and LC). A random-effects meta-analysis was conducted to pool the effects of cCBT on depression and anxiety symptom scores compared with the control groups. Study quality was assessed using the Cochrane Collaboration Risk of Bias tool. 

RESULTS: A total of 16 randomized controlled trials were eligible for inclusion in this review, of which 13 (81%) were included in the meta-analysis. The quality of the studies was mixed, with 5 (31%) studies rated as good overall, 2 (13%) rated as fair, and 9 (56%) rated as poor. Small but statistically significant effects of cCBT were detected, with cCBT conditions showing lower symptom scores at follow-up compared with control conditions for both anxiety (standardized mean difference -0.21, 95% CI -0.33 to -0.09; I&lt;sup&gt;2&lt;/sup&gt;=36.2%) and depression (standardized mean difference -0.23, 95% CI -0.39 to -0.07; I&lt;sup&gt;2&lt;/sup&gt;=59.5%). Secondary analyses suggested that cCBT may be comparable with alternative, active interventions (such as face-to-face therapy or treatment as usual). 

CONCLUSIONS: This meta-analysis reinforces the efficacy of cCBT for the treatment of anxiety and depression and is the first to examine this exclusively in adolescents. Future research could aim to identify the active components of these interventions toward optimizing their development and increasing the feasibility and acceptability of cCBT in this age group. TRIAL REGISTRATION: PROSPERO CRD42019141941; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=141941.
AN  - 35404263
AU  - Wickersham,
AU  - A.
AU  - Barack,
AU  - T.
AU  - Cross,
AU  - L.
AU  - Downs,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/29842
L1  - internal-pdf://2794743200/Computerized Cognitive Behavioral Therapy-2022.pdf
PY  - 2022
SP  - e29842
T2  - Journal of Medical Internet Research
TI  - Computerized Cognitive Behavioral Therapy for Treatment of Depression and Anxiety in Adolescents: Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35404263
VL  - 24
ER  -
TY  - JOUR
AB  - Children can develop post-traumatic stress disorder (PTSD) and mental health symptoms after traumatic events. This meta-analysis evaluated the influence of moderators of cognitive behavioural trauma treatment (CBTT) with caregiver involvement in traumatized children. A total of 28 studies were included, with 23 independent samples and 332 effect sizes, representing the data of 1931 children (M age = 11.10 years, SD = 2.36). Results showed a significant medium overall effect (d = 0.55, t = 2.478, p = 0.014), indicating CBTT with caregiver involvement was effective in treating PTSD (d = 0.70), with somewhat smaller effect sizes for internalizing, externalizing, social, cognitive and total problems (0.35 &lt; d &gt; 0.48). The positive treatment effect was robust; we found somewhat smaller effect sizes at follow-up (d = 0.49) compared to post-test (d = 0.57) assessments. Furthermore, several sample (i.e. child&#039;s age, gender, and trauma event), programme (i.e. the duration of treatment, number of sessions), study (i.e. control condition, type of instrument, informant, type of sample), and publication (i.e. publication year and impact factor) characteristics moderated the treatment outcomes of the child. In sum, the results of our meta-analysis might help to improve the effectiveness of cognitive behavioural trauma treatment for youth with PTSD, and guide the development of innovative trauma interventions that involve caregivers. Implications for theory and practice are discussed.
AN  - 36178528
AU  - Somers,
AU  - K.
AU  - Spruit,
AU  - A.
AU  - Stams,
AU  - G.
AU  - J.
AU  - Vandevelde,
AU  - S.
AU  - Lindauer,
AU  - R.
AU  - Assink,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-022-02088-2
L1  - internal-pdf://3575374307/Somers-2022-Identifying effective moderators o.pdf
PY  - 2022
SP  - 30
T2  - European Child &amp; Adolescent Psychiatry
TI  - Identifying effective moderators of cognitive behavioural trauma treatment with caregiver involvement for youth with PTSD: a meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36178528
UR  - https://link.springer.com/article/10.1007/s00787-022-02088-2
UR  - https://link.springer.com/content/pdf/10.1007/s00787-022-02088-2.pdf
VL  - 30
ER  -
TY  - JOUR
AB  - **OBJECTIVES:** 
Our objective was to assess the effects of mental health interventions for children, adolescents, and adults not quarantined or undergoing treatment due to COVID-19 infection. 

**METHODS:** 
We searched 9 databases (2 Chinese-language) from December 31, 2019, to March 22, 2021. We included randomised controlled trials of interventions to address COVID-19 mental health challenges among people not hospitalised or quarantined due to COVID-19 infection. We synthesized results descriptively due to substantial heterogeneity of populations and interventions and risk of bias concerns. 

**RESULTS:** 
We identified 9 eligible trials, including 3 well-conducted, well-reported trials that tested interventions designed specifically for COVID-19 mental health challenges, plus 6 other trials with high risk of bias and reporting concerns, all of which tested standard interventions (e.g., individual or group therapy, expressive writing, mindfulness recordings) minimally adapted or not specifically adapted for COVID-19. Among the 3 well-conducted and reported trials, 1 (N = 670) found that a self-guided, internet-based cognitive-behavioural intervention targeting dysfunctional COVID-19 worry significantly reduced COVID-19 anxiety (standardized mean difference [SMD] 0.74, 95% confidence interval [CI], 0.58 to 0.90) and depression symptoms (SMD 0.38, 95% CI, 0.22 to 0.55) in Swedish general population participants. A lay-delivered telephone intervention for homebound older adults in the United States (N = 240) and a peer-moderated education and support intervention for people with a rare autoimmune condition from 12 countries (N = 172) significantly improved anxiety (SMD 0.35, 95% CI, 0.09 to 0.60; SMD 0.31, 95% CI, 0.03 to 0.58) and depressive symptoms (SMD 0.31, 95% CI, 0.05 to 0.56; SMD 0.31, 95% CI, 0.07 to 0.55) 6-week post-intervention, but these were not significant immediately post-intervention. No trials in children or adolescents were identified. 

**CONCLUSIONS:** 
Interventions that adapt evidence-based strategies for feasible delivery may be effective to address mental health in COVID-19. More well-conducted trials, including for children and adolescents, are needed.
AN  - 35275494
AU  - Bonardi,
AU  - O.
AU  - Wang,
AU  - Y.
AU  - Li,
AU  - K.
AU  - Jiang,
AU  - X.
AU  - Krishnan,
AU  - A.
AU  - He,
AU  - C.
AU  - Sun,
AU  - Y.
AU  - Wu,
AU  - Y.
AU  - Boruff,
AU  - J.
AU  - T.
AU  - Markham,
AU  - S.
AU  - Rice,
AU  - D.
AU  - B.
AU  - Thombs-Vite,
AU  - I.
AU  - Tasleem,
AU  - A.
AU  - Santo,
AU  - T.
AU  - D.
AU  - Yao,
AU  - A.
AU  - Azar,
AU  - M.
AU  - Agic,
AU  - B.
AU  - Fahim,
AU  - C.
AU  - Martin,
AU  - M.
AU  - S.
AU  - Sockalingam,
AU  - S.
AU  - Turecki,
AU  - G.
AU  - Benedetti,
AU  - A.
AU  - Thombs,
AU  - B.
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/07067437211070648
L1  - internal-pdf://1189506923/Effects of COVID-19 Mental Health Interve-2022.pdf
PY  - 2022
SP  - 7067437211070648
T2  - Canadian Journal of Psychiatry - Revue Canadienne de Psychiatrie
TI  - Effects of COVID-19 Mental Health Interventions Among Children, Adolescents, and Adults Not Quarantined or Undergoing Treatment Due to COVID-19 Infection: A Systematic Review of Randomised Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35275494
ER  -
TY  - JOUR
AB  - **Introduction:** 
Children with cancer experience symptom distress which has been correlated with decreased quality of life (QOL). Creative arts therapy (CAT) encompasses the therapeutic use of creative arts which may improve QOL among children with cancer by affecting symptoms. Therefore, the research question was asked: Does CAT affect symptoms of pain, nausea, fatigue, anxiety, and mood in children with cancer? 

**Methods:** 
Based on the study question, a comprehensive literature search of PubMed, CINAHL, PsycINFO, and Embase was completed. Inclusion criteria limited articles to specific symptom outcomes in two-group intervention studies in the English language. Selected articles were confirmed for inclusion by the study team, followed by group discussion to develop matrices with levels of evidence based on the Grading of Recommendations Assessment, Development, and Evaluation (Grade) guidelines. Results: Initial searches revealed 1,391 articles, screened to 44 for systematic review. Based on the inclusion criteria, 11 articles remained. Four studies had evidence levels graded as low, three were low to moderate, and four were moderate. Outcomes of mood and anxiety were measured in five studies, pain in four, fatigue in two, and nausea in one study. 

**Discussion:** 
Psychological outcomes were measured more commonly than physical outcomes. Evidence reached a moderate grade in four studies. 

**Summary:** 
Through this synthesis of intervention studies with CAT in children with cancer, improvement in distressing symptoms has potential, but the state of the science for symptom management with CAT could be strengthened for nurses to promote CAT to improve QOL among children with cancer. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-40013-007
AU  - Raybin,
AU  - J.
AU  - L.
AU  - Harnke,
AU  - B.
AU  - Hendricks-Ferguson,
AU  - V.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/27527530211059432
L1  - internal-pdf://2170162474/27527530211059432.cleaned.pdf
PY  - 2022
SP  - 60-71
T2  - Journal of Pediatric Hematology / Oncology Nursing
TI  - Does creative arts therapy improve distressing symptoms in children with cancer? A synthesis of extant literature
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc19&amp;AN=2023-40013-007
VL  - 39
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
To evaluate intervention characteristics and components within behavioral sleep interventions in school-aged children with ADHD and examine evidence related to effectiveness. 

**METHOD**
A systematic review was conducted using PsycINFO, Embase, MEDLINE, PubMed, and OpenGray. The subsequent meta-analysis used sleep outcomes to produce comparable effect sizes (Hedges&#039; g) and compare intervention effects between randomized controlled trials and pre-post studies. 

**RESULTS**
Eleven articles satisfied the inclusion criteria (562 children, across all groups, aged 5-14 years, M = 8.71). Studies reported improvements in sleep although there was marked heterogeneity between studies and limited use of objective sleep measures within them. On average, intervention groups improved more than control groups in the five randomized controlled trials (-0.46, 95% CI = [-0.58, -0.35], k = 4). 

**CONCLUSION**
The findings support the use of behavioral sleep interventions for school-aged children with ADHD. Findings suggest that brief, individualized intervention may be more effective than standardized.
AN  - 35758199
AU  - Malkani,
AU  - M.
AU  - K.
AU  - Pestell,
AU  - C.
AU  - F.
AU  - Sheridan,
AU  - A.
AU  - M.
AU  - C.
AU  - Crichton,
AU  - A.
AU  - J.
AU  - Horsburgh,
AU  - G.
AU  - C.
AU  - Bucks,
AU  - R.
AU  - S.
DB  - Alerts 6_2022.enl
DO  - /10.1177/10870547221106239
L1  - internal-pdf://2877082329/10870547221106239.cleaned.pdf
PY  - 2022
SP  - 10870547221106239
T2  - Journal of Attention Disorders
TI  - Behavioral Sleep Interventions for Children With ADHD: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35758199
ER  -
TY  - JOUR
AB  - Dopaminergic dysfunction is thought to be central to schizophrenia symptomatology. Previous meta-analyses of prodopaminergic drugs in schizophrenia have important limitations, and also did not include dopamine D2/D3 partial agonists. We investigated the effect of medications which increase dopamine signalling on schizophrenia symptoms by meta-analysing double-blind, placebo-controlled RCTs. 59 RCTs were included: 29 of prodopaminergic treatments, 30 of partial agonists. Partial agonists were significantly superior to placebo against positive (SMD=-0.33,p = 1.2 x10-17), negative (SMD=-0.29,p = 2.2 x 10-31) and total symptoms (SMD =-0.39,p = 1.7 x 10-30) in schizophrenia. There were no significant differences between pooled pro-dopaminergic drugs and placebo in any symptom domain. In subgroup analysis of five studies where patients were selected for negative symptom severity, ar/modafinil was superior to placebo against negative symptoms (SMD=-0.34,p = 0.037). These data favour the clinical use of partial agonists for negative symptoms in schizophrenia, with clinically meaningful effect sizes. Our findings also suggest a benefit for ar/modafinil in patients with predominant negative symptoms. Future trials of other prodopaminergic therapies and dopamine partial agonists in patients with predominant negative symptoms are warranted. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-48074-001
AU  - Osugo,
AU  - M.
AU  - Whitehurst,
AU  - T.
AU  - Shatalina,
AU  - E.
AU  - Townsend,
AU  - L.
AU  - O&#039;Brien,
AU  - O.
AU  - Mak,
AU  - T.
AU  - L.
AU  - A.
AU  - McCutcheon,
AU  - R.
AU  - Howes,
AU  - O.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.neubiorev.2022.104568
L1  - internal-pdf://3828767692/Dopamine partial agonists and prodopamine-2022.pdf
PY  - 2022
T2  - Neuroscience and Biobehavioral Reviews Vol 135 2022, ArtID 104568
TI  - Dopamine partial agonists and prodopaminergic drugs for schizophrenia: Systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-48074-001
UR  - https://www.sciencedirect.com/science/article/pii/S0149763422000574?via%3Dihub
VL  - 135
ER  -
TY  - JOUR
AB  - **Introduction:** 
School-based child sexual abuse intervention programs were developed to educate the school children to protect them from sexual abuse. The programs were evaluated to make sure the interventions were effective in reducing child sexual abuse cases (CSA). This review aimed to determine the effectiveness of the school-based child sexual abuse intervention programs in the new millennium era (2000-2021) in improving the knowledge, skills, and attitude of school children under 18 years old toward child sexual abuse. 

**Methods:** 
A systematic search was conducted through MEDLINE (PubMed), EBSCO, and SCOPUS databases to collect full English articles related to school-based CSA intervention programs published from 2000 to 2021. 

**Results:** 
A total of 29 studies from randomized control trial and quasi-experimental from several countries was analyzed. Comparisons within group of pre-post intervention for knowledge, skills, and attitude were measured by standardized mean difference (SMD) and 95% CI of -1.06 (95% CI: -1.29, -0.84), -0.91 (95% CI: -1.2, -0.61), and -0.51 (95% CI: -3.61, 0.58), respectively. Meanwhile for between intervention and control group comparisons, the SMD of knowledge was 0.9 (95% CI: 0.63, 1.18), skills was 0.39 (95% CI: 0.07, 0.71), and attitude was 1.76 (95% CI: 0.46, 3.07). 

**Conclusion:** 
The programs were found to be effective in improving the knowledge, skills, and attitude of the students from pre-intervention to post-intervention and between the intervention and control groups. 

**Systematic Review Registration:** www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022312383, identifier: CRD42022312383.
AN  - 35937243
AU  - Che
AU  - Yusof,
AU  - R.
AU  - Norhayati,
AU  - M.
AU  - N.
AU  - Mohd
AU  - Azman,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpubh.2022.909254
L1  - internal-pdf://3085662775/Che Yusof-2022-Effectiveness of school-based c.pdf
PY  - 2022
SP  - 909254
T2  - Frontiers in Public Health
TI  - Effectiveness of school-based child sexual abuse intervention among school children in the new millennium era: Systematic review and meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35937243
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355675/pdf/fpubh-10-909254.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - A systematic review and meta-analysis was conducted where we evaluated the effects of Parent Management Training (PMT), Parent-Child Interaction Therapy (PCIT) and PMT combined with child cognitive behavioral therapy (CBT) using data from 25 RCTs on children with clinical levels of disruptive behavior (age range 2-13 years). 

Results showed that PMT (g = 0.64 [95% CI 0.42, 0.86]) and PCIT (g = 1.22 [95% CI 0.75, 1.69]) were more effective than waiting-list (WL) in reducing parent-rated disruptive behavior, and PMT also in improving parental skills (g = 0.83 [95% CI 0.67, 0.98]) and child social skills (g = 0.49 [95% CI 0.30, 0.68]). PCIT versus WL had larger effects in reducing disruptive behavior than PMT versus WL. 

In the few studies found, the addition of child CBT to PMT did not yield larger effects than PMT or WL. These results support offering PMT to children with clinical levels of disruptive behavior and highlight the additional benefits of PCIT for younger ages.
AN  - WOS:000821983900002
AU  - Helander,
AU  - M.
AU  - Asperholm,
AU  - M.
AU  - Wetterborg,
AU  - D.
AU  - Ost,
AU  - L.
AU  - G.
AU  - Hellner,
AU  - C.
AU  - Herlitz,
AU  - A.
AU  - Enebrink,
AU  - P.
DB  - Alerts 6_2022.enl
DO  - 10.1007/s10578-022-01367-y
L1  - internal-pdf://2939471132/Helander-The Efficacy of Parent Management Tra.pdf
PY  - 2022
SP  - 18
T2  - Child Psychiatry &amp; Human Development
TI  - The Efficacy of Parent Management Training With or Without Involving the Child in the Treatment Among Children with Clinical Levels of Disruptive Behavior: A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000821983900002
UR  - https://link.springer.com/content/pdf/10.1007/s10578-022-01367-y.pdf
ER  -
TY  - JOUR
AB  - This systematic and meta-analytic review investigated the effects of media health literacy (MHL) interventions in school settings on adolescents&#039; body image. 

Twenty one intervention-control comparisons reported in 16 studies were identified. The following attributes were extracted from each study for a systematic review: Study time-period and country location, sample composition, school atmosphere, unit of random assignment, theoretical perspective, intervention-control comparison, co-interventions, number of overall and MHL sessions, length of MHL sessions, and outcomes measured. 

The meta-analysis of effect sizes for three outcomes of interest related to body image showed consistent changes in the desired negative direction as expected: body image concerns (g = -0.25, k = 19); eating concerns (g = -0.18, k = 19); thin-internalization attitudes (g = -0.40, k = 12); and combined (g = -0.25, k = 21). Homogeneity analysis for the combined effect size and moderator analyses for gender composition of intervention group, number of overall intervention sessions, number of MHL specific intervention sessions within the overall intervention, and time length of MHL intervention session all showed absence of moderators. 

However, all study samples except one were of European origin and so caution should be exercised when generalizing to other cultures that may have different standards of female ideal body type.
AN  - 32873082
AU  - Zuair,
AU  - A.
AU  - A.
AU  - Sopory,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/10410236.2020.1813954
L1  - internal-pdf://2027531195/Effects of Media Health Literacy School-B-2022.pdf
PY  - 2022
SP  - 20-28
T2  - Health Communication
TI  - Effects of Media Health Literacy School-Based Interventions on Adolescents&#039; Body Image Concerns, Eating Concerns, and Thin-Internalization Attitudes: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=32873082
UR  - https://www.tandfonline.com/doi/full/10.1080/10410236.2020.1813954
VL  - 37
ER  -
TY  - JOUR
AB  - **Background**
Autism spectrum disorder (ASD) might be associated with oxidative stress, and antioxidants are commonly used in the treatment of young people with ASD. However, the evidence about the effectiveness of these interventions remains debatable. We performed a meta-analysis to evaluate the effect of antioxidants on the symptoms of patients with autism. Methods: Data sources: PubMed and Web of Science databases. 

**Study selection**
We selected placebo-controlled, double-blind, randomized clinical trials published until February 2021 to evaluate the efficacy of antioxidant interventions on ASD. Data analysis: Aberrant Behavior Checklist (ABC), Repetitive Behavior Scale-Revised (RBS), Social Responsiveness Scale (SRS), Developmental Behavior Checklist (DBC) and Clinical Global Impressions Severity scale (CGI-S) were used to evaluate the 22 different symptom outcomes. The Hedges-adjusted g value was used to estimate the effect of each dietary intervention relative to the placebo. Results: In this meta-analysis, we examined 13 double-blind randomized clinical trials, comprising a total of 570 patients with ASD: 293 in the intervention group and 277 in the placebo group. Antioxidants (N-acetylcysteine (NAC), other antioxidants) are more effective than placebos in improving the irritability among symptoms in the ABC and communication disturbance symptoms in the DBC. There was a good trend of improvement in the stereotypic behavior symptoms in the ABC. Treatment with NAC antioxidants showed a good trend of improvement in irritability in the ABC and symptoms of hyperactivity. The effect size was small, and there was a low risk of statistical heterogeneity and publication bias. 

**Limitations** 
The number of studies in this meta-analysis was small and the sample size was small. 

**Conclusion**
This meta-analysis suggests that antioxidant intervention has a potential role in the management of some symptoms in patients with ASD, and indicates the feasibility of using antioxidants to treat autism in the future.
AN  - WOS:000721036500002
AU  - Liu,
AU  - Y.
AU  - Y.
AU  - Yang,
AU  - Z.
AU  - M.
AU  - Du,
AU  - Y.
AU  - Shi,
AU  - S.
AU  - Cheng,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.pnpbp.2021.110476
L1  - internal-pdf://3559729731/1-s2.0-S0278584621002359-main.cleaned.pdf
PY  - 2022
SP  - 9
T2  - Progress in Neuro-Psychopharmacology &amp; Biological Psychiatry
TI  - Antioxidant interventions in autism spectrum disorders: A meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000721036500002
VL  - 113
ER  -
TY  - JOUR
AB  - INTRODUCTION: 
Medical procedures are often accompanied by pain and anxiety in pediatric patients. A relatively new technique to reduce pediatric pain and anxiety is Virtual Reality (VR). VR is both applied as a distraction tool and as an exposure tool to prepare patients for medical procedures. Research into the application of VR in medical settings is rapidly evolving. This meta-analysis is an update of the meta-analysis of Eijlers et al. investigating the effectiveness of VR as an intervention tool on pain and anxiety in pediatric patients undergoing medical procedures. 

METHODS: 
We searched the databases Embase, Medline, Web of Science Core Collection, Cochrane Central Register of Controlled Trials and PsycINFO. For each of these databases, different search strategies were developed. The search period from the meta-analysis from Eijlers et al., reaching until April 2018, was extended to December 2020. Pain and anxiety outcomes during medical procedures were compared for VR and standard care conditions for various medical procedures. 

RESULTS: 
The search yielded 1824 articles, of which 13 met our inclusion criteria. Combined with 13 articles of Eijlers&#039; review study, this resulted in 26 articles. VR was applied as distraction (n = 23) during medical procedures or as exposure (n = 4) before medical procedures. The effect of VR distraction was mostly studied in patients during venous access (n = 10). The overall weighted standardized mean difference (SMD) for VR distraction was -0.67 (95% CI, -0.89 - -0.45; p &lt; .001) on patient-reported pain (based on 21 studies) and -0.74 (95% CI, -1.00 - -0.48; p &lt; .001) on patient-reported anxiety (based on 10 studies). The effect of VR as an exposure tool on patient-reported anxiety was significant too (SMD = -0.58; 95% CI, -1.15 - -0.01; p &lt; .05) 

DISCUSSION: 
The current updated systematic review and meta-analysis indicates that VR is a usefool tool to reduce pain and anxiety in pediatric patients undergoing a range of medical procedures as it significantly decreases pain and anxiety outcomes when compared to care as usual.
AN  - 35993398
AU  - Tas,
AU  - F.
AU  - Q.
AU  - van
AU  - Eijk,
AU  - C.
AU  - A.
AU  - M.
AU  - Staals,
AU  - L.
AU  - M.
AU  - Legerstee,
AU  - J.
AU  - S.
AU  - Dierckx,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/pan.14546
L1  - internal-pdf://4111043702/Tas-2022-Virtual Reality in Pediatrics, Effect.pdf
PY  - 2022
SP  - 22
T2  - Paediatric Anaesthesia
TI  - Virtual Reality in Pediatrics, Effects on Pain and Anxiety: A Systematic Review and Meta-Analysis Update
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35993398
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/pan.14546?download=true
VL  - 22
ER  -
TY  - JOUR
AB  - **Aim:** 
To identify which interventions are supported by evidence and the quality of that evidence in very young children with or at high likelihood for autism spectrum disorder (ASD) to improve child outcomes. 

**Method(s):** 
We conducted an overview of reviews to synthesize early intervention literature for very young children with or at high likelihood for ASD. Cochrane guidance on how to perform overviews of reviews was followed. Comprehensive searches of databases were conducted for systematic reviews and meta-analyses between January 2009 and December 2020. Review data were extracted and summarized and methodological quality was assessed. Primary randomized controlled trial evidence was summarized and risk of bias assessed. This overview of reviews was not registered. 

**Result(s):** 
From 762 records, 78 full texts were reviewed and seven systematic reviews and meta-analyses with 63 unique studies were identified. Several interventional approaches (naturalistic developmental behavioral intervention, and developmental and behavioral interventions) improved child developmental outcomes. Heterogeneity in design, intervention and control group, dose, delivery agent, and measurement approach was noted. Inconsistent methodological quality and potential biases were identified. 

**Interpretation(s):** 
While many early interventional approaches have an impact on child outcomes, study heterogeneity and quality had an impact on our ability to draw firm conclusions regarding which treatments are most effective. Advances in trial methodology and design, and increasing attention to mitigating measurement bias, will advance the quality of the ASD early intervention evidence base. Copyright &copy; 2022 Mac Keith Press.
AN  - 2016974855
AU  - Franz,
AU  - L.
AU  - Goodwin,
AU  - C.
AU  - D.
AU  - Rieder,
AU  - A.
AU  - Matheis,
AU  - M.
AU  - Damiano,
AU  - D.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/dmcn.15258
L1  - internal-pdf://4070580466/Early intervention for very young childre-2022.pdf
PY  - 2022
T2  - Developmental Medicine and Child Neurology.
TI  - Early intervention for very young children with or at high likelihood for autism spectrum disorder: An overview of reviews
UR  - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1469-8749
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dmcn.15258?download=true
ER  -
TY  - JOUR
AB  - Treatment efficacy for eating disorders (EDs) is modest and guidelines differ. We summarized findings/quality of (network) meta-analyses (N)MA of randomized controlled trials (RCTs) in EDs. Systematic meta-review ((N)MA of RCTs, ED, active/inactive control), using (anorexia or bulimia or eating disorder) AND (meta-analy*) in PubMed/PsycINFO/Cochrane database up to December 15th, 2020. Standardized mean difference, odds/risk ratio vs control were summarized at end of treatment and follow-up. Interventions involving family (family-based therapy, FBT) outperformed active control in adults/adolescents with anorexia nervosa (AN), and in adolescents with bulimia nervosa (BN). In adults with BN, individual cognitive behavioural therapy (CBT)-ED had the broadest efficacy versus active control; also, antidepressants outperformed active. In mixed age groups with binge-eating disorder (BED), psychotherapy, and lisdexamfetamine outperformed active control. Antidepressants, stimulants outperformed placebo, despite lower acceptability, as did CBT-ED versus waitlist/no treatment. Family-based therapy is effective in AN and BN (adolescents). CBT-ED has the largest efficacy in BN (adults), followed by antidepressants, as well as psychotherapy in BED (mixed). Medications have short-term efficacy in BED (adults).
AN  - 36084848
AU  - Monteleone,
AU  - A.
AU  - M.
AU  - Pellegrino,
AU  - F.
AU  - Croatto,
AU  - G.
AU  - Carfagno,
AU  - M.
AU  - Hilbert,
AU  - A.
AU  - Treasure,
AU  - J.
AU  - Wade,
AU  - T.
AU  - Bulik,
AU  - C.
AU  - M.
AU  - Zipfel,
AU  - S.
AU  - Hay,
AU  - P.
AU  - Schmidt,
AU  - U.
AU  - Castellini,
AU  - G.
AU  - Favaro,
AU  - A.
AU  - Fernandez-Aranda,
AU  - F.
AU  - Il
AU  - Shin,
AU  - J.
AU  - Voderholzer,
AU  - U.
AU  - Ricca,
AU  - V.
AU  - Moretti,
AU  - D.
AU  - Busatta,
AU  - D.
AU  - Abbate-Daga,
AU  - G.
AU  - Ciullini,
AU  - F.
AU  - Cascino,
AU  - G.
AU  - Monaco,
AU  - F.
AU  - Correll,
AU  - C.
AU  - U.
AU  - Solmi,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.neubiorev.2022.104857
L1  - internal-pdf://3021785683/1-s2.0-S0149763422003463-main.cleaned.pdf
PY  - 2022
SP  - 104857
T2  - Neuroscience &amp; Biobehavioral Reviews
TI  - Treatment of eating disorders: A systematic meta-review of meta-analyses and network meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36084848
UR  - https://www.sciencedirect.com/science/article/pii/S0149763422003463?via%3Dihub
VL  - 142
ER  -
TY  - JOUR
AB  - For children with autism or intellectual and developmental disabilities who also have complex communication needs, communication is a necessary skill set to increase independence and quality of life. Understanding the how, where, and communication style being taught is important for identifying deficits in the field as well as which interventions are most effective. This meta-analysis sought to identify effectiveness among different settings, behavioral strategies, and moderator variables. A systematic search and screening process identified 114 eligible studies with 330 participants; overall outcomes indicate that augmentative and alternative communication interventions were effective with Tau effects ranging from 0.53 to 1.03 and log response ratio effects ranging from 0.21 to 2.90. However, no instructional context variables systematically predicted differences in intervention effectiveness.
AN  - WOS:000784827000002
AU  - Ganz,
AU  - J.
AU  - B.
AU  - Pustejovsky,
AU  - J.
AU  - E.
AU  - Reichle,
AU  - J.
AU  - Vannest,
AU  - K.
AU  - J.
AU  - Foster,
AU  - M.
AU  - Haas,
AU  - A.
AU  - N.
AU  - Pierson,
AU  - L.
AU  - M.
AU  - Wattanawongwan,
AU  - S.
AU  - Bernal,
AU  - A.
AU  - Chen,
AU  - M.
AU  - Skov,
AU  - R.
AU  - Smith,
AU  - S.
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40489-022-00314-w
L1  - internal-pdf://3455918712/Considering Instructional Contexts in AAC Inte.pdf
PY  - 2022
SP  - 15
T2  - Review Journal Of Autism And Developmental Disorders
TI  - Considering Instructional Contexts in AAC Interventions for People with ASD and/or IDD Experiencing Complex Communicative Needs: a Single-Case Design Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000784827000002
UR  - https://link.springer.com/article/10.1007/s40489-022-00314-w
UR  - https://link.springer.com/content/pdf/10.1007/s40489-022-00314-w.pdf
ER  -
TY  - JOUR
AB  - Promoting Alternative Thinking Strategies (PATHS) is a widely-used social emotional learning program for preschool and elementary school students. The purpose of this review is to examine its effects, and explore the moderation effects of methodological and implementation features on intervention effectiveness. 

Using stringent inclusion criteria, 20 qualified studies and 177 effect sizes involving 30,454 participants were included. Results showed that the overall effect size of PATHS was 0.11. In particular, the effect size of PATHS on social emotional skills (ES = 0.16) was the largest compared with other outcome domains, including attitude or relations (ES = 0.08), emotional well-being (ES = 0.02), prosocial behaviors (ES = 0.04), conduct problems (ES = 0.06), and academic performance (ES = 0.05).

 PATHS had no different impact whether it was implemented in the universal or target contexts. Research design, sample size, and intervention dosage could moderate the effectiveness of PATHS significantly, and dosage was the predominant factor in determining the effects of PATHS. Policy and practical implications were discussed.
AD  - Shi, Jieping. Department of Educational Administration and Policy, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.Cheung, Alan C K. Department of Educational Administration and Policy, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.Ni, Aohua. Department of Educational Administration and Policy, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
AN  - 36571043
AU  - Shi,
AU  - J.
AU  - Cheung,
AU  - A.
AU  - C.
AU  - K.
AU  - Ni,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyg.2022.1030572
DP  - Ovid Technologies
J2  - Front Psychol
L1  - internal-pdf://2036815951/fpsyg-13-1030572.cleaned.pdf
LA  - English
M3  - Systematic Review
N1  - Shi, JiepingCheung, Alan C KNi, Aohua
PY  - 2022
SP  - 1030572
T2  - Frontiers in Psychology
TI  - The effectiveness of Promoting Alternative Thinking Strategies program: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36571043
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36571043&amp;id=doi:10.3389%2Ffpsyg.2022.1030572&amp;issn=1664-1078&amp;isbn=&amp;volume=13&amp;issue=&amp;spage=1030572&amp;pages=1030572&amp;date=2022&amp;title=Frontiers+in+Psychology&amp;atitle=The+effectiveness+of+Promoting+Alternative+Thinking+Strategies+program%3A+A+meta-analysis.&amp;aulast=Shi&amp;pid=%3Cauthor%3EShi+J%3C%2Fauthor%3E%3CAN%3E36571043%3C%2FAN%3E%3CDT%3ESystematic+Review%3C%2FDT%3E
VL  - 13
ER  -
TY  - JOUR
AB  - Abstract Background Adopted children and children placed in foster care are at increased risk of developing a range of mental health, behavioural, and psychosocial adjustment problems. Previous studies suggest that due to early experiences of separation and loss some children may have difficulties forming a secure attachment relationship with the adoptive/foster parents. Objectives The objectives of the present review were: (1) to assess the efficacy of attachment-based interventions on measures of favourable parent/child outcomes (attachment security, dyadic interaction, parent/child psychosocial adjustment, behavioural and mental health problems, and placement breakdown) within foster and adoptive families with children aged between 0 and 17 years. (2) to identify factors that appear to be associated with more effective outcomes and factors that modify intervention effectiveness (e.g., age of the child at placement and at intervention start, programme duration, programme focus). Search Methods Relevant studies were identified through electronic searches of bibliographic databases, governmental and grey literature repositories, hand search in specific targeted journals, citation tracking, contact to international experts and Internet search engines. The database searches were carried out to October 2020. Selection Criteria The interventions of interest were parenting interventions aimed at helping the foster/adopted children and their parents to form or sustain a secure attachment relationship. The interventions had to be at least partly informed by attachment theory. Data Collection and Analysis The total number of potentially relevant studies constituted 17.822 hits after duplicates were removed. A total of 44 studies (27 different populations) met the inclusion criteria and were critically appraised by the review authors. Due to critical study quality, missing numeric data and re-use of the same data, only 24 studies analysing 16 different populations could be used in the data synthesis (children, N&thinsp;=&thinsp;1302; parents, N&thinsp;=&thinsp;1344). Meta-analysis using both child and parent outcomes were conducted on each metric separately. All analyses were inverse variance weighted using random effects statistical models. Random effects weighted mean effect sizes were calculated using 95% confidence intervals (CIs). When possible, we conducted moderator analysis using meta-regression and single factor sub group moderator analysis. Sensitivity analysis were conducted across study design and domains of the risk of bias assessment. Main Results Ten studies analysed the effect of attachment-based interventions on the overall psychosocial adjustment of foster or adopted children as reported by their caregivers post intervention. Measures used include the Child Behaviour Checklist, The Strengths and Difficulties Questionnaire, Brief Infant&ndash;Toddler Social and Emotional Assessment (BITSEA) and Eyberg Child Behaviour Inventory. The random effects weighted standardised mean difference (SMD) favouring the intervention group was 0.37 (95% CI, 0.10&ndash;0.65) and statistically significant. Three studies analysed the effects of attachment-based interventions on the observed attachment security of foster and adopted children as measured by independent observation. Measures include the Strange Situation Procedure, Attachment Q-Set, and The Emotional Availability Clinical Screener. The random effects weighted SMD was 0.59 (95% CI, &minus;0.40&ndash;1.57) and not statistically significant. Four studies analysed the effect of attachment-based interventions on positive child behaviour post intervention as measured by independent observation of video-taped interaction between the child and caregivers. Measures include Disruptive Behaviour Diagnostic Observation Schedule (DB-DOS) and Emotional Availability Scales). The random effects weighted SMD was 0.39 (95% CI, 0.14&ndash;0.64) and statistically significant. Ten studies analysed the effect of attachment-based interventions on positive parenting behaviour post intervention as measured by independent observati n of video-taped interaction between the child and caregivers or coding of audio-taped recordings of parental speech. Measures include Adapted Ainsworth Scales for sensitivity and noninterference, Measurement of Empathy in Adult&ndash;Child Interaction, The Dyadic Parent&ndash;Child Interaction Coding System, Reflective functioning scale, and Emotional Availability Scales. The random effects weighted SMD was 1.56 (95% CI, 0.81&ndash;2.31) and statistically significant. Nine studies analysed the effect of attachment-based interventions on self-reported post intervention parenting stress (Parenting Stress Index). The random effects weighted SMD was 0.24 (95% CI, 0.03&ndash;0.46.) and statistically significant. Three studies analysed the effect of attachment-based interventions on parental post intervention self-reported depressive symptoms (Beck Depression Inventory). The random effects weighted SMD was 0.59 (95% CI, &minus;0.08&ndash;1.25.) and not statistically significant. Follow-up analyses were carried out for the outcomes externalising behaviour, positive parenting, and parenting stress, but due to the low number of studies, results should be viewed with caution. Results of the single factor sub group moderator analysis suggest that it cannot be ruled out the effects differ depending on whether the interventions take place in the family home or in a clinical setting. However, it is unclear which location is associated with more positive effects as our findings differ between child and parent outcomes. Results of the sensitivity analysis showed no appreciable changes in the results following the removal of any of the studies in any of the analyses. Authors&#039; Conclusions Parenting interventions based on attachment theory increase positive parent/child interactional behaviours, decrease parenting stress, and increase the overall psychosocial adjustment of children in foster and adoptive families postintervention. Due to the low number of studies evidence regarding the effects of attachment-based parenting interventions on attachment security and disorganised attachment in foster and adopted children was inconclusive. Theoretically, it is possible that child attachment security and/or attachment disorganisation cannot change within the relatively short period of time that parenting interventions typically last. It is possible that if postintervention improvements in parenting behaviours are sustained over time, it may lead to possible improvement in child attachment security and a decrease in child disorganised attachment. Thus, more longitudinal research is needed. Furthermore, evidence regarding the long-term effects of attachment-based parenting interventions on any outcomes was inconclusive due to too few studies, but findings suggest that attachment-based interventions increase positive parenting behaviour at follow-up points 3&ndash;6 months after the intervention. No study included in the present review provided a measure of placement stability or breakdown as an outcome, which could be used in the meta-analysis. This further emphasises the need for future longitudinal research in prevention of placement breakdown.
AU  - Dalgaard,
AU  - Nina
AU  - T.
AU  - Filges,
AU  - Trine
AU  - Viinholt,
AU  - Bjørn
AU  - C.
AU  - A.
AU  - Pontoppidan,
AU  - Maiken
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/cl2.1209
L1  - internal-pdf://1601736307/Campbell Systematic Reviews - 2022 - Dalgaard.pdf
PY  - 2022
SP  - e1209
T2  - Campbell Systematic Reviews
TI  - Parenting interventions to support parent/child attachment and psychosocial adjustment in foster and adoptive parents and children: A systematic review
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/cl2.1209
VL  - 18
ER  -
TY  - JOUR
AB  - **BACKGROUND**
In clinical practice guidelines there is no consensus about the medications that should be initially offered to children and young people with Tourette&#039;s syndrome. To provide a rigorous evidence base that could help guide decision making and guideline development, we aimed to compare the efficacy, tolerability, and acceptability of pharmacological interventions for Tourette&#039;s syndrome.

**METHODS**
For this systematic review and network meta-analysis, we searched the Cochrane Central Register of Controlled Trials, Embase, PsycINFO, PubMed, Web of Science, the WHO International Clinical Trials Registry Platform, and ClinicalTrials.gov, for published and unpublished studies from database inception to Nov 19, 2021. We included double-blind randomised controlled trials of any medication administered as a monotherapy for at least 1 week against another medication or placebo in children and adolescents (aged &gt;=4 years and &lt;=18 years), adults (&gt;18 years), or both, diagnosed with Tourette&#039;s syndrome according to standardised criteria. We excluded studies that exclusively recruited participants with comorbid attention-deficit hyperactivity disorder or obsessive-compulsive disorder. The primary outcome was change in severity of tic symptoms (efficacy). Secondary outcomes were treatment discontinuations due to adverse events (tolerability) and for any reason (acceptability). Pharmacological interventions were examined considering medication categories and medications individually in separate analyses. Summary data were extracted and pooled with a random-effects network meta-analysis to calculate standardised mean differences for efficacy and odds ratios for tolerability and acceptability, with 95% CIs. The Confidence in Network Meta-Analysis (CINeMA) framework was used to assess the certainty of evidence. The protocol was pre-registered in PROSPERO (CRD42022296975).

**FINDINGS**
 Of the 12 088 records identified through the database search, 88 records representing 39 randomised controlled trials were included in the network meta-analysis; these 39 randomised controlled trials comprised 4578 participants (mean age 11.8 [SD 4.5] years; 3676 [80.8%] male participants) and evaluated 23 individual medications distributed across six medication categories. When considering medication categories, first-generation (standardised mean difference [SMD] -0.65 [95% CI -0.79 to -0.51]; low certainty of evidence) and second-generation (-0.71 [-0.88 to -0.54]; moderate certainty of evidence) antipsychotic drugs, as well as alpha-2 agonists (-0.21 [-0.39 to -0.03]; moderate certainty of evidence), were more efficacious than placebo. First-generation and second-generation antipsychotic drugs did not differ from each other (SMD 0.06 [95% CI -0.14 to 0.25]; low certainty of evidence). However, both first-generation (SMD 0.44 [95% CI 0.21 to 0.66]) and second-generation (0.49 [0.25 to 0.74]) antipsychotic drugs outperformed alpha-2 agonists, with moderate certainty of evidence. Similar findings were observed when individual medications were considered: aripiprazole (SMD -0.60 [95% CI -0.83 to -0.38]), haloperidol (-0.51 [-0.88 to -0.14]), olanzapine (-0.83 [-1.49 to -0.18]), pimozide (-0.48 [-0.84 to -0.12]), risperidone (-0.66 [-0.98 to -0.34]), and clonidine (-0.20 [-0.37 to -0.02]) all outperformed placebo, with moderate certainty of evidence. Antipsychotic medications did not differ from each other, but there was low to very low certainty of evidence for these comparisons. However, aripiprazole (SMD -0.40 [95% CI -0.69 to -0.12]) and risperidone (-0.46 [-0.82 to -0.11]) outperformed clonidine, with moderate certainty of evidence. Heterogeneity or inconsistency only emerged for a few comparisons. In terms of tolerability and acceptability, there were no relevant findings for any of the efficacious medication categories or individual medications against each other or placebo, but there was low to very low certainty of evidence associated with these comparisons.

**INTERPRETATION**
Our analyses show that antipsychotic drugs are the most efficacious intervention for Tourette&#039;s syndrome, while alpha-2 agonists are also more efficacious than placebo and could be chosen by those who elect not to take antipsychotic drugs. Shared decision making about the degree of tic-related severity and distress or impairment, the trade-offs of efficacy and safety between antipsychotic drugs and alpha-2 agonists, and other highly relevant individual factors that could not be addressed in the present analysis, should guide the choice of medication for children and young people with Tourette&#039;s syndrome.

**FUNDING** None.
AD  - Farhat, Luis C. Child Study Center, Yale University School of Medicine, New Haven, CT, USA; Department of Psychiatry, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil; Department of Psychiatry, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.Behling, Emily. Child Study Center, Yale University School of Medicine, New Haven, CT, USA.Landeros-Weisenberger, Angeli. Child Study Center, Yale University School of Medicine, New Haven, CT, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.Levine, Jessica L S. Child Study Center, Yale University School of Medicine, New Haven, CT, USA.Macul Ferreira de Barros, Pedro. Department of Psychiatry, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.Wang, Ziyu. Child Study Center, Yale University School of Medicine, New Haven, CT, USA.Bloch, Michael H. Child Study Center, Yale University School of Medicine, New Haven, CT, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. Electronic address: michael.bloch@yale.edu.
AN  - 36528030
AU  - Farhat,
AU  - L.
AU  - C.
AU  - Behling,
AU  - E.
AU  - Landeros-Weisenberger,
AU  - A.
AU  - Levine,
AU  - J.
AU  - L.
AU  - S.
AU  - Macul
AU  - Ferreira
AU  - de
AU  - Barros,
AU  - P.
AU  - Wang,
AU  - Z.
AU  - Bloch,
AU  - M.
AU  - H.
DA  - Dec 14
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/S2352-4642(22)00316-9
DP  - Ovid Technologies
J2  - Lancet Child Adolesc Health
L1  - internal-pdf://0741560728/1-s2.0-S2352464222003169-main.cleaned.pdf
LA  - English
N1  - Using Smart Source ParsingDecFarhat, Luis CBehling, EmilyLanderos-Weisenberger, AngeliLevine, Jessica L SMacul Ferreira de Barros, PedroWang, ZiyuBloch, Michael HS2352-4642(22)00316-9
PY  - 2022
SP  - 14
T2  - The Lancet Child &amp; Adolescent Health
TI  - Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette&#039;s syndrome: a systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36528030
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36528030&amp;id=doi:10.1016%2FS2352-4642%2822%2900316-9&amp;issn=2352-4642&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2022&amp;title=The+Lancet+Child+%26+Adolescent+Health&amp;atitle=Comparative+efficacy%2C+tolerability%2C+and+acceptability+of+pharmacological+interventions+for+the+treatment+of+children%2C+adolescents%2C+and+young+adults+with+Tourette%27s+syndrome%3A+a+systematic+review+and+network+meta-analysis.&amp;aulast=Farhat&amp;pid=%3Cauthor%3EFarhat+LC%3C%2Fauthor%3E%3CAN%3E36528030%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 14
ER  -
TY  - JOUR
AB  - Research suggests that transgender and non-binary (TGNB) individuals experience lower levels of psychological well-being than the general population. Although practice recommendations and guidelines exist, there is a paucity of studies evaluating the effects of psychological interventions on this group. 

This systematic review aimed to synthesize and analyze existing empirical affirmative psychological interventions for TGNB individuals to assess their efficacy. Eight databases (PubMed, Web of Science, PsycINFO, Scopus, LILACS, Cochrane, ProQuest, Google Scholar) were searched from January 2010 to June 2022 to identify relevant studies. Included studies needed to be randomized controlled trials, quasi-experimental, or uncontrolled pre-post. 

Twenty-two articles were included, of which eight had TGNB participants only, two had mixed samples with separated outcome data for TGNB participants, and 12 had mixed samples with no disaggregated data. Experimental designs, participant samples, assessed variables, and type of interventions varied widely across studies, thus preventing comparisons. 

Overall results suggest improvements in psychological distress, depression, anxiety, suicidality, substance-related risk behaviors, coping skills/emotion regulation, stress appraisal, self-esteem, self-acceptance, social support, minority stress, resilience, hope, positive identity, and identity acceptance, although conclusions are limited by moderate-to-high risk of bias. Future research should implement more consistent and rigorous methodological designs to assess and compare intervention efficacy.
AD  - Exposito-Campos, Pablo. Department of Clinical and Health Psychology and Research Methods, Faculty of Psychology, University of the Basque Country, Tolosa Hiribidea 70, 20018 Donostia-San Sebastian, Gipuzkoa, Spain; Predoctoral Research Fellowship Program of the Department of Education of the Government of the Basque Country, Spain. Electronic address: pablo.exposito@ehu.eus.Perez-Fernandez, Jose Ignacio. Department of Clinical and Health Psychology and Research Methods, Faculty of Psychology, University of the Basque Country, Tolosa Hiribidea 70, 20018 Donostia-San Sebastian, Gipuzkoa, Spain.Salaberria, Karmele. Department of Clinical and Health Psychology and Research Methods, Faculty of Psychology, University of the Basque Country, Tolosa Hiribidea 70, 20018 Donostia-San Sebastian, Gipuzkoa, Spain.
AN  - 36512905
AU  - Exposito-Campos,
AU  - P.
AU  - Perez-Fernandez,
AU  - J.
AU  - I.
AU  - Salaberria,
AU  - K.
DA  - Nov 29
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.cpr.2022.102229
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://3409531116/1-s2.0-S0272735822001143-main.cleaned (1).pdf
LA  - English
M3  - Review
N1  - Exposito-Campos, PabloPerez-Fernandez, Jose IgnacioSalaberria, KarmeleS0272-7358(22)00114-3
PY  - 2022
SP  - 102229
T2  - Clinical Psychology Review
TI  - Empirically supported affirmative psychological interventions for transgender and non-binary youth and adults: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36512905
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36512905&amp;id=doi:10.1016%2Fj.cpr.2022.102229&amp;issn=0272-7358&amp;isbn=&amp;volume=100&amp;issue=&amp;spage=102229&amp;pages=102229&amp;date=2022&amp;title=Clinical+Psychology+Review&amp;atitle=Empirically+supported+affirmative+psychological+interventions+for+transgender+and+non-binary+youth+and+adults%3A+A+systematic+review.&amp;aulast=Exposito-Campos&amp;pid=%3Cauthor%3EExposito-Campos+P%3C%2Fauthor%3E%3CAN%3E36512905%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 100
ER  -
TY  - JOUR
AB  - OBJECTIVES: To assess the effectiveness and safety of risperidone and aripiprazole in children with autism spectrum disorder (ASD). 

DESIGN AND SETTING: Overview of systematic reviews (SRs). 

SEARCH METHODS: In October 2021, we searched Cochrane Central Register of Controlled Trials, MEDLINE, Embase, PsycInfo and Epistemonikos placing no restrictions on language or date of publication. 

PARTICIPANTS: Children aged 12 years or less with ASD.

INTERVENTIONS: Risperidone and aripiprazole with no dosage restrictions. 

DATA COLLECTION AND ANALYSIS: We rated the methodological quality of the included SRs using A Measurement Tool to Assess Systematic Reviews (AMSTAR 2). We reported the Grading of Recommendations, Assessment, Development and Evaluation certainty of the evidence according to the analysis conducted by the authors of the included SRs. 

MAIN OUTCOMES MEASURED: A multidisciplinary group of experts agreed on analysing nine critical outcomes evolving core and non-core ASD symptoms. 

PATIENT AND PUBLIC INVOLVEMENT: Organisations of parents of children with ASD were involved during part of the process, participating in external revision of the final version of the report for the Chilean Ministry of Health with no additional comments (ID 757-22-L120 DIPRECE, Ministry of Health, Chile). The organisations involved were: Fundacion Union Autismo y Neurodiversidad, Federacion Nacional de Autismo, Voceria Autismo del Sur, and Voceria Autismo del Norte. 

RESULTS: We identified 22 SRs within the scope of this overview, of which 16 were of critically low confidence according to AMSTAR 2 and were excluded from the analysis. Both aripiprazole and risperidone were effective for reducing autism symptoms severity, repetitive behaviours, inappropriate language, social withdrawal and behavioural problems compared with placebo. The certainty of the evidence for most outcomes was moderate. Risperidone and aripiprazole are associated with metabolic and neurological adverse events. Follow-up was short termed. 

CONCLUSIONS: We found that aripiprazole and risperidone probably reduce symptom severity at short-term follow-up but may also cause adverse events. High-quality and updated SRs and larger randomised controlled trials with longer term follow-up are needed on this topic. Overview protocol: Prospero crd42020206535.
AN  - 35101925
AU  - Fieiras,
AU  - C.
AU  - Chen,
AU  - M.
AU  - H.
AU  - Escobar
AU  - Liquitay,
AU  - C.
AU  - M.
AU  - Meza,
AU  - N.
AU  - Rojas,
AU  - V.
AU  - Franco,
AU  - J.
AU  - V.
AU  - A.
AU  - Madrid,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/bmjebm-2021-111804
L1  - internal-pdf://1571944872/Risperidone and aripiprazole for autism s-2022.pdf
PY  - 2022
SP  - 31
T2  - BMJ Evidence based Medicine
TI  - Risperidone and aripiprazole for autism spectrum disorder in children: an overview of systematic reviews
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35101925
UR  - https://ebm.bmj.com/content/early/2022/01/31/bmjebm-2021-111804
UR  - https://ebm.bmj.com/content/ebmed/early/2022/01/31/bmjebm-2021-111804.full.pdf
VL  - 31
ER  -
TY  - JOUR
AB  - **Background**: While multiple treatments for pediatric anxiety and obsessive compulsive disorder (OCD) are efficacious, little is known about their cost-effectiveness. In response, we sought to provide relevant information through systematic review and cost-effectiveness simulation. 

**Method(s)**: We evaluated the cost-effectiveness of treatment for pediatric anxiety and OCD in two ways. First, we conducted a systematic review following PRISMA guidelines. Second, we evaluated cost-effectiveness for antidepressant medication, cognitive behavioral therapy, and their combination via a simulation that integrated information from the Truven MarketScan database and the NIMH National Database for Clinical Trials Related to Mental Illness. 

**Result(s)**: Both systematic review and simulation found antidepressant medication and cognitive behavioral therapy to be cost-effective for pediatric anxiety and OCD. Antidepressant medication was the least costly approach, and cognitive behavioral therapy provided additional cost-effectiveness, especially for OCD. Limitation(s): During systematic review, relatively few articles provided information about both costs and effectiveness. While there was a notable margin of error to support multiple interventions as cost-effective, limited prior research decreased precision of point estimates and comparisons between interventions. 

**Conclusion(s)**: Both antidepressant medication and cognitive behavioral therapy were found to be cost-effective for pediatric anxiety and OCD. Results supported investment from third party payers, who serve as critical gatekeepers that can increase treatment dissemination. However, more precise information would better inform the exact amount of investment needed, especially with regard to selection decisions between active interventions. Cost-effectiveness research would benefit from systematic collection of data on treatment costs and quality of life in future clinical trials. Copyright &copy; 2021 Elsevier B.V.
AN  - 2015467790
AU  - De
AU  - Nadai,
AU  - A.
AU  - S.
AU  - Quast,
AU  - T.
AU  - Little,
AU  - T.
AU  - B.
AU  - Westerberg,
AU  - K.
AU  - Patyk,
AU  - K.
AU  - C.
AU  - Monahan,
AU  - M.
AU  - F.
AU  - Storch,
AU  - E.
AU  - A.
AU  - Gregory,
AU  - S.
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2021.10.127
L1  - internal-pdf://2849089148/De Nadai-2022.pdf
PY  - 2022
SP  - 110-118
T2  - Journal of Affective Disorders
TI  - Intervention cost-effectiveness for pediatric anxiety and OCD: A systematic review and integrated database model
UR  - http://www.elsevier.com/locate/jad
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0165032721011101?via%3Dihub
VL  - Part A. 298
ER  -
TY  - JOUR
AB  - Animal-assisted interventions are frequently used to stimulate and improve different skills in children with and without disabilities. However, the heterogeneity of AAI studies in preschool children is large, including different health conditions, duration, outcomes, study design or therapy animals. Therefore, the current study aims to summarize all intervention procedures and provide an updated analysis of the effectiveness of AAI intervention in the early childhood. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA), a systematic search was conducted in two databases: Pubmed (MedLine) and Web of Science. The risk of bias was assessed using the Evidence Project risk of bias tool. A total of 319 articles were identified and 17 were finally included in the qualitative synthesis. Due to the large heterogeneity in terms of study design, intervention, and sample characteristics, it was not possible to conduct a meta-analysis. Animal-assisted interventions might lead to a positive impact on physical, physiological, psychosocial, and language skills in preschool children. These enhancements may be observed both in healthy children and in those with different health conditions, such as intellectual disabilities, cerebral palsy, autism disorder, or Down syndrome. Results must be interpreted with caution due to the large heterogeneity and risk of bias in the included articles.
AN  - 36424180
AU  - Lavin-Perez,
AU  - A.
AU  - M.
AU  - Rivera-Martin,
AU  - B.
AU  - Lobato-Rincon,
AU  - L.
AU  - L.
AU  - Villafaina-Dominguez,
AU  - S.
AU  - Collado-Mateo,
AU  - D.
DB  - Alerts 6_2022.enl
DO  - /10.1177/13591045221142115
L1  - internal-pdf://2723400635/Lavin-Perez_2022.pdf
PY  - 2022
SP  - 13591045221142115
T2  - Clinical Child Psychology &amp; Psychiatry
TI  - Benefits of animal-Assisted interventions in preschool children: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36424180
ER  -
TY  - JOUR
AB  - A handful of meta-analytic studies of have documented the impact of couple relationship education (CRE) programs on couple outcomes. Recently, an increasing number of studies have examined whether CRE also impacts a wider set of family outcomes. Basic research demonstrates the importance of positive couple relationship quality for effective parenting and child well-being. 

This meta-analytic study investigates whether CRE programs have effects on coparenting, parenting, and child outcomes. 

We analyzed 40 control-group studies and found small, average effect sizes for coparenting (d = 0.073, p &lt; 0.01) and child well-being/behavior (d = 0.056, p &lt; 0.01), but not for parenting (d = 0.023, ns). (Effect sizes for 12 1-group/pre-post studies are reported in online supplemental appendix S2.) Moderator analyses of control-group studies found differences in several methodological and participant characteristics that provide potential clues for future research and improving the practice of CRE to improve children&#039;s well-being. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-25465-001
AU  - Hawkins,
AU  - A.
AU  - J.
AU  - Hill,
AU  - M.
AU  - S.
AU  - Eliason,
AU  - S.
AU  - A.
AU  - Simpson,
AU  - D.
AU  - M.
AU  - Hokanson,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10826-022-02229-w
L1  - internal-pdf://0528325003/Do couple relationship education programs-2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Journal of Child and Family Studies
TI  - Do couple relationship education programs affect coparenting, parenting, and child outcomes? A meta-analytic study
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-25465-001
UR  - https://link.springer.com/content/pdf/10.1007/s10826-022-02229-w.pdf
ER  -
TY  - JOUR
AB  - **Background:** 
No established pharmacological treatment is available for the core symptoms of autism spectrum disorder (ASD). This study aimed at investigating the efficacy of antidepressants for the core and associated symptoms of ASD. 

**Method(s):** 
We searched PubMed, Embase, ClinicalKey, Cochrane CENTRAL, ScienceDirect, Web of Science and ClinicalTrials.gov using the keywords &quot;ASD&quot; and &quot;antidepressants.&quot; We searched from database inception to June 2021 for randomized controlled trials of antidepressant use in patients with ASD. We calculated pooled effect sizes based on a random-effects model. 

**Result(s):** 
Analysis of 16 studies with 899 participants showed improvements in restricted and repetitive behaviours (effect size = 0.27) and global symptoms (effect size = 1.0) in patients with ASD taking antidepressants versus those taking placebos (p &lt;= 0.01). We found no differences between the 2 groups (p &gt;= 0.36) in terms of dropout rate (odds ratio [OR] = 1.17) or rate of study discontinuation because of adverse events (OR = 1.05). We also noted improvements in irritability and hyperactivity in the antidepressant group (Hedges g = 0.33 and 0.22, respectively, both p &lt; 0.03). Subgroup analyses showed significant effects of medication type (i.e., clomipramine was better than SSRIs) and age (antidepressants were more effective in adults than in children or adolescents) on both restricted and repetitive behaviours and global improvement (p &lt; 0.05). Meta-regression demonstrated that better therapeutic effects were associated with lower symptom severity and older age. 

**Limitation(s):** 
The small effect sizes and variations in treatment response that we found warrant further study. 

**Conclusion(s):** 
Our results supported the effectiveness of antidepressants for global symptoms and symptom subdomains of ASD, with tolerable adverse effects. Low symptom severity and adulthood were associated with better outcomes. Copyright &copy; 2022 CMA Impact Inc.
AN  - 2017703372
AU  - Liang,
AU  - S.
AU  - C.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Fan,
AU  - H.
AU  - Y.
AU  - Chung,
AU  - W.
AU  - Tzang,
AU  - R.
AU  - F.
AU  - Hung,
AU  - K.
AU  - C.
AU  - Chiu,
AU  - H.
AU  - J.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Yeh,
AU  - P.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1503/jpn.210191
L1  - internal-pdf://1019839248/Liang-2022-Therapeutic effects of antidepressa.pdf
PY  - 2022
SP  - E299-E310
T2  - Journal of Psychiatry and Neuroscience
TI  - Therapeutic effects of antidepressants for global improvement and subdomain symptoms of autism spectrum disorder: a systematic review and meta-analysis
UR  - http://www.jpn.ca
UR  - https://www.jpn.ca/content/jpn/47/4/E299.full.pdf
VL  - 47(4)
ER  -
TY  - JOUR
AB  - **Background:** 
Needle-related pain, fear, and anxiety can be a deterrent to treatments in children and adolescents. Virtual reality (VR) can be used to manage the poor experience of needle procedures. 

**Objective:**
This meta-analysis aimed to examine the effects of VR on pain, fear, and anxiety related to needle procedures in children and adolescents. Methods: PubMed, EMBASE, and the Cochrane Library were searched for potentially eligible studies published up to June 2021. The outcomes were pain assessed by the Wong-Baker Faces Pain Scale (WBS) or Faces Pain Scale-Revised (FPS-R), and Visual Analog Scale (VAS), fear assessed by Children&#039;s Fear Scale (CFS), and anxiety assessed by Children&#039;s Anxiety Meter (CAM), VAS, or CFS. Because of expected heterogeneity among studies, all analyses were conducted using the random-effects model. 

**Results:** 
Ten studies were included (571 children in the VR group and 575 in the control group). Based on the WBS, VR reduced pain, either self-reported (WMD = -2.17, 95%CI: -3.37, -0.97), parent-reported (WMD = -3.52, 95%CI: -4.62, -2.42), nurse-reported (WMD = -3.29, 95%CI: -5.59, -0.99), and physician/investigator-reported (WMD = -3.48, 95%CI: -5.93, -1.04). Using the FPS-R, VR reduced needle-related pain compared with controls (WMD = -0.85, 95%CI: -1.64, -0.06). Similar results were observed for fear (children/adolescents: WMD = -1.52, 95%CI: -2.18, -0.86; parents: WMD = -1.71, 95%CI: -2.30, -1.13; nurses: WMD = -1.55, 95%CI: -2.47, -0.63; physicians/investigators: WMD = -0.59, 95%CI: -1.00, -0.18) and anxiety (self-reported: WMD = -2.79, 95%CI: -4.07, -1.54; parent-reported: WMD = -3.87, 95%CI: -5.58, -2.15; nurse-reported: WMD = -4.64, 95%CI: -6.56, -2.71; physician/investigator-reported: WMD = -2.06, 95%CI: -4.13, -0.00). 

**Conclusion:** 
A VR-based intervention could reduce needle-related pain, fear, and anxiety in children and adolescents.
AN  - 35519646
AU  - Wang,
AU  - Y.
AU  - Guo,
AU  - L.
AU  - Xiong,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyg.2022.842847
L1  - internal-pdf://0278479476/Effects of Virtual Reality-Based Distract-2022.pdf
PY  - 2022
SP  - 842847
T2  - Frontiers in Psychology
TI  - Effects of Virtual Reality-Based Distraction of Pain, Fear, and Anxiety During Needle-Related Procedures in Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35519646
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9063726/pdf/fpsyg-13-842847.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - OBJECTIVES: To review and meta-analyze existing evidence regarding the impact of school start times (SSTs) on youth sleep and developmental outcomes considering the moderating effects of youth and school characteristics. Scopus, ScienceDirect, JSTOR, Pubmed, PsychInfo, ERIC, Proquest, EBSCO, and Google Scholar were used through 2019 to select studies measuring (1) school start time and (2) sleep or other developmental outcomes. Data from 28 studies and 1 774 509 participants were extracted and analyzed using random-effects models with robust variance estimation. 

RESULTS: Later SSTs were associated with better overall developmental outcomes, longer sleep duration, and less negative mood. Specifically, new SSTs between 8:30 and 8:59 were associated with better outcomes than 8:00 to 8:29 start times. Later SSTs were more strongly associated with lower levels of sleepiness for high school (versus middle school) youth, and youth in private (versus public) schools reported better sleep and later wake times with later SSTs. Although this meta-analysis suggests an overall benefit of later SSTs, there was limited research to test outcomes such as sleep hygiene, naps, and behavioral and physical health outcomes. 

CONCLUSIONS: There is converging evidence that later SSTs are associated with better overall developmental outcomes, longer sleep duration, and less negative mood. More research needs to consider student and school characteristics to obtain reliable estimates related to possible differences by sex, race, school size, percent free/reduced lunch, and percent minority.
AN  - 35593065
AU  - Yip,
AU  - T.
AU  - Wang,
AU  - Y.
AU  - Xie,
AU  - M.
AU  - Ip,
AU  - P.
AU  - S.
AU  - Fowle,
AU  - J.
AU  - Buckhalt,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1542/peds.2021-054068
L1  - internal-pdf://0455558498/School Start Times, Sleep, and Youth Outc-2022.pdf
PY  - 2022
SP  - 01
T2  - Pediatrics
TI  - School Start Times, Sleep, and Youth Outcomes: A Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=35593065
UR  - https://watermark.silverchair.com/peds_2021054068.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtIwggLOBgkqhkiG9w0BBwagggK_MIICuwIBADCCArQGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMBZXq9qm_1qnduFGAAgEQgIIChQpTvQ5jp4SVh9CLR7tz_wV3QrZ55GafemeHurMoK5Y_UMzcHn_X_FsbGSOZIt7igRwi3uTZYvEjzdGYu0pYlglAWeKnNg5wsHTbKt_IERmCj-zEp8YUU6v_Qz9jgQfv6J6sewZ6XLjbfTNJt3BoEEDMyIIrgKRiW6YmkrClkyQr5oyr0MKzeuE2o3VNwoRgG1eRCfxPn1SfGVMq4k2LR7KYcg7zwBhHyKT894gkxFVSc4Ir1GUCxsDoAsWaGIepf_G0s_M-Kdh5ILHxireoqqBR00Yz_f8YiQKP6eKE48m6NbrwVM15R5NGgG-FrzIOD0Dp7yCsYyhklFsA2Y6h4HFhz04T4JUYR67M3q1sNWDxh5D-v_GTOOhxTYUKQ1mUidb4Hefs089sFho6aDB-h4XRBPegnbW62OnYaTP7CnCNsfkB7FvRb-rXqI6gHTTbb4Enaq1abzSQw5grNV8UCvyRk5vbMvBD24i_ir5FfBXFZ9IwlSsD_JAgkITNT4aLzzoXu2GBMVZJJ-n5RPcC9vA-ZLuYOjh1gEJBBaMDmVEalgcXChUNfHUxXZlmwYH8njXM8W2gtQVKzcHdsPo9gg98YxjhPHQpmPJz8JhkjOowPCkE7iQTM3pvWijFrikTe_EtHicmrFG8enDIY5LLLH0ZMh8LBVa4tE4fjNfAfgkbZ46ESxiquSm-mSZ2aI_8B7C6zIpKZkPS1xt7_pMfd9wNhxi05UhdhqoW9oKpgcI8WHUOTQ6bFwIMK6e1co9T0BjM5h9fDtvLpVhkrm3Z2947yN73H48jwIzyU7IXUXOtGjBeRkJSDVwj88hrxXoQXXh8dqX9w4KxiO31t3Hz_PUbn4avUA
VL  - 149
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Psychotic disorders produce important morbidity and disability in children and adolescents. There have been few relevant treatment trials, encouraging assessment of research aimed at testing efficacy and safety of antipsychotics for juveniles. We aimed to compare the short- and long-term efficacy and safety of antipsychotics to treat psychotic disorders among children and adolescents. 

**METHODS**
Four major bibliographic databases (PubMed, MEDLINE, PsycINFO, and EMBASE) were searched for clinical trials of antipsychotics in children or adolescents, from database inception to May 2021. We searched for clinical trials comparing antipsychotics with control conditions for juvenile psychosis based on blinded review by 2 independent investigators (C.S.Y. and M.L.). We adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analyses and applied the Cochrane risk-of-bias tool to appraise study quality. One reviewer (A.B.) performed data abstraction which was confirmed by 2 independent, blinded reviewers (C.S.Y. and M.L.). Primary outcomes were scores rating psychosis symptoms and dichotomized retention in treatment protocols versus dropouts because of adverse events. Effect sizes were pooled using frequentist random-effects network meta-analysis modeling to generate summary rate ratios (RRs) and Cohen d standardized mean differences. 

**RESULTS**
Systematic searching generated 1330 unique records. Of these, short-term (n = 15, for 6 [3-12] weeks) and long-term (n = 10, for 12 [6-60] months) treatment trials involved 2208 (39.2% females; median age, 15.3 years), and 1366 subjects (35.0% females; median age, 15.6 years), respectively. Short-term reduction of psychosis scores ranked clozapine (d = -1.35; 95% confidence interval [CI], -1.97 to -0.73]), molindone (-1.22; 95% CI, -1.68 to -0.75), olanzapine (-1.12; 95% CI, -1.44 to -0.81), and risperidone (-0.93; 95% CI, -1.22 to -0.63) as the most effective agents. In longer-term treatment, only lurasidone was effective. Clozapine (RR, 12.8) and haloperidol (RR, 5.15) led to more all-cause and adverse event-related dropouts. There were few trials/drug (1 each for aripiprazole, asenapine, lurasidone, molindone, paliperidone, and ziprasidone, short term; aripiprazole, clozapine, haloperidol, lurasidone, and molindone, long-term). Heterogeneity and inconsistency were high, especially in long-term trials, without evidence of publication bias. 

**CONCLUSIONS**
Some antipsychotics were effective and tolerated short term, but longer-term evidence was very limited. The overall paucity of trials and of adequate controls indicates that more well-designed randomized controlled trials are required for adequate assessment of antipsychotic drug treatment for juveniles. Systematic review registration: Prospero crd42021232937.
AN  - 35020712
AU  - Yee,
AU  - C.
AU  - S.
AU  - Bahji,
AU  - A.
AU  - Lolich,
AU  - M.
AU  - Vazquez,
AU  - G.
AU  - H.
AU  - Baldessarini,
AU  - R.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/JCP.0000000000001506
L1  - internal-pdf://0085436996/Comparative Efficacy and Tolerability of-2022.pdf
PY  - 2022
SP  - 10
T2  - Journal of Clinical Psychopharmacology
TI  - Comparative Efficacy and Tolerability of Antipsychotics for Juvenile Psychotic Disorders: A Systematic Review and Network Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35020712
VL  - 10
ER  -
TY  - JOUR
AB  - Poverty alleviation programs, such as cash transfers and monetary grants, may not only lift people out of poverty but, some argue, may improve mental health as well. However, to date, the impact of such programs on children and adolescents&#039; mental health is unclear. We carried out a systematic review and meta-analysis of poverty alleviation interventions providing monetary support and reporting mental health outcomes in 0-19 year olds in low-, middle-, and high-income countries. We searched 11 databases for research published between January 1, 1990 and June 1, 2020 and included interventions offering unconditional and/or conditional monetary support and reporting mental health outcomes. After screening 7,733 unique articles, we included 14 papers (16,750 children and adolescents at follow-up) in our narrative summary. We meta-analyzed data on internalizing symptoms from 8 papers (13,538 children and adolescents analyzed). This indicated a small but significant reduction in adolescents&#039; internalizing problems postintervention compared to control (odds ratio 0.72, 95% confidence interval 0.59-0.88, p &lt; .01; I&lt;sup&gt;2&lt;/sup&gt; = 67%, tau&lt;sup&gt;2&lt;/sup&gt; = 0.05, p &lt; .01). Our narrative synthesis provides further support for the overall effectiveness of cash programs but also notes that monetary support alone may not be sufficient in extreme risk settings and that imposing conditions may be actively harmful for the mental health of adolescent girls. We provide causal evidence that monetary interventions reduce internalizing symptoms of adolescents experiencing poverty. We recommend that future programming thoughtfully considers whether to apply conditions as part of their interventions and highlight the importance of providing additional comprehensive support for children and adolescents living in extreme risk settings.
AN  - 35430146
AU  - Zaneva,
AU  - M.
AU  - Guzman-Holst,
AU  - C.
AU  - Reeves,
AU  - A.
AU  - Bowes,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jadohealth.2022.02.011
L1  - internal-pdf://2580967518/The Impact of Monetary Poverty Alleviatio-2022.pdf
PY  - 2022
SP  - 13
T2  - Journal of Adolescent Health
TI  - The Impact of Monetary Poverty Alleviation Programs on Children&#039;s and Adolescents&#039; Mental Health: A Systematic Review and Meta-Analysis Across Low-, Middle-, and High-Income Countries
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35430146
UR  - https://www.sciencedirect.com/science/article/pii/S1054139X22003329?via%3Dihub
VL  - 13
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis explores the effectiveness of teacher interventions supporting children with externalizing behaviors based on teacher and child outcomes. A systematic search was conducted using 5 electronic databases. From 5714 papers, 31 papers that included interventions delivered directly to teachers and aimed to benefit either teachers and/or children with externalizing behaviors were included. The review focused on qualified teachers working with children aged 2-13. The results of the current meta-analysis revealed a positive effect of teacher intervention on teacher and child outcomes, including the increased use of teacher-appropriate strategies, as well as significant and moderate improvements in teacher-child closeness, and small reductions in teacher-child conflict. For child outcomes, the interventions reduced externalizing behavior problems and ADHD symptoms and enhanced prosocial behavior. Only one fully blinded analysis for conduct problems was possible and revealed a moderate but significant reduction in favor of intervention. These findings provide evidence to support the role of teacher interventions for both teachers and children with externalizing behaviors. Future research should include more PBLIND measurements so that MPROX findings can be confirmed. More research should be done to evaluate the influence of teacher interventions on teachers&#039; well-being.
AN  - 36093124
AU  - Aldabbagh,
AU  - R.
AU  - Glazebrook,
AU  - C.
AU  - Sayal,
AU  - K.
AU  - Daley,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10864-022-09491-4
L1  - internal-pdf://1610062989/Aldabbagh-2022-Systematic Review and Meta-Anal.pdf
PY  - 2022
SP  - 1-42
T2  - Journal of Behavioral Education
TI  - Systematic Review and Meta-Analysis of the Effectiveness of Teacher Delivered Interventions for Externalizing Behaviors
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36093124
UR  - https://link.springer.com/content/pdf/10.1007/s10864-022-09491-4.pdf
ER  -
TY  - JOUR
AB  - **Introduction** 
Autism spectrum disorder (ASD) is a neurodevelopmental disorder. The discovery of the influence of gut microbiota on mental illness opens up new research avenues for the role of gut microbiota modifiers, such as probiotics or prebiotics, as a potential course of treatment. Potential treatments have received considerable attention in recent years. 

**Aim** 
The meta-analysis only included clinical controlled trials to explore whether probiotics and prebiotics can improve the overall severity of ASD symptoms in children, the severity of gastrointestinal (GI) problems and the comorbid psychopathlology in ASD. 

**Gap statement** 
Although systematic reviews have been conducted in this area in the past, most of them are mixed experimental designs, and the reliability of the conclusions remains to be determined. To the best of our knowledge, no systematic review of randomized controlled trials (RCTs) has been conducted. 

**Methodology** 
A meta analysis used a combination of subject terms and free words, or used keywords, titles, and abstracts to conduct in PubMed, Web of Science, Embase, and Cochrane Library to identify studies relevant to the current review. 

**Result** 
The results of the meta-analysis showed that probiotics and prebiotics did not significantly improve the severity of ASD patients, GI problems and comorbid psychopathlology in ASD, and the result is contradictory to the previous literatures. 

**Conclusion** 
Since there are relatively few clinical controlled trials that can be included, the results of this study still need to be further verified in the clinic. In the future, more randomized controlled studies, more research populations, and the use of more professional clinicians may provide more robust research results.
AN  - 35438624
AU  - Song,
AU  - W.
AU  - Zhang,
AU  - M.
AU  - Teng,
AU  - L.
AU  - Wang,
AU  - Y.
AU  - Zhu,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1099/jmm.0.001510
L1  - internal-pdf://3721486932/Prebiotics and probiotics for autism spec-2022.pdf
PY  - 2022
T2  - Journal of Medical Microbiology
TI  - Prebiotics and probiotics for autism spectrum disorder: a systematic review and meta-analysis of controlled clinical trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35438624
UR  - https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.001510
VL  - 71
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Attention deficit hyperactivity disorder (ADHD) is a mental illness that can place a significant burden on individuals, their families, and society. East Asian Herbal Medicine (EAHM) has long been used in East Asian nations to treat mental illness in children. Nevertheless, the evidence for the effectiveness of EAHM for the treatment of ADHD is insufficient. A systematic review was performed to examine the effectiveness and safety. In addition, research on core herbal combinations was also conducted to help clinicians in their prescription selection.

**MATERIALS AND METHODS**
This systematic review and meta-analysis were prepared according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The following databases were searched: 4 English databases (PubMed, Cochrane Library, Cumulative Index to Nursing &amp; Allied Health Literature (CINAHL), EMBASE), 4 Korean databases (Korean Studies Information Service System (KISS), Research Information Service System (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Korea Citation Index (KCI)), 2 Chinese databases (Chinese National Knowledge Infrastructure Database (CNKI), Wanfang Data), and 1 Japanese database (CiNii) database. The publication bias was evaluated using funnel plots. GRADE pro was used to evaluate the evidence of the study. The core herb combination of EAHM used in this study was revealed using apriori algorithm-based association rule mining.

**RESULTS**
This review assessed 42 studies that evaluated 3484 children and adolescents. In meta-analysis, EAHM monotherapy had a similar clinical efficacy rate to conventional medicine (CM) (n = 2166; random effects RR 1.09, 95% CI 1.05 to 1.13; heterogeneity chi2= 25.08, df = 23, p = 0.35, I&lt;sup&gt;2&lt;/sup&gt;=8%). EAHM-combined therapy showed a better clinical efficacy rate than when conventional therapy was used alone (n = 746; fixed effects RR 1.19, 95% CI 1.12 to 1.26; heterogeneity chi2= 11.80, df = 9, p = 0.22, I&lt;sup&gt;2&lt;/sup&gt;=24%). For adverse events, EAHM had a lower incidence than conventional therapy. In GRADE pro, each outcome varied from moderate to very low quality. The constituents of the herb combinations with consistent association rules were Fossilia Ossis Mastodi, Polygalae Radix, and Acori Graminei Rhizoma.

**CONCLUSION**
EAHM monotherapy has similar effects to CM but with fewer side effects. Hence, it will be helpful for children with ADHD suffering from the side effects of CM. EAHM-combined therapy has a better effect than conventional therapy. Accordingly, it will be useful for children with ADHD who do not respond to treatment with conventional therapy. Nevertheless, more well-designed studies will be needed to confirm this in the future.
AD  - Lee, Ju Hyun. Department of Pediatrics of Korean Medicine, Graduate School of Dongguk University, Pildong-ro 1-Gil 30, Jung-gu, Seoul, 04620, Republic of Korea.Jo, Hee Geun. Naturalis Inc. 6, Daewangpangyo-ro, Bundang-gu, Seongnam 13549, Gyeonggi-do, Republic of Korea; Department of Herbal Pharmacology, College of Korean Medicine, Gachon University, 1342 Seongnamdae-ro, Sujeong-gu, Seongnam 13120, Gyeonggi-do, Republic of Korea. Electronic address: jho3366@hanmail.net.Min, Sang Yeon. Department of Pediatrics of Korean Medicine, Korean Medicine Hospital, Dongguk University Medical Center, Dongguk-ro 27, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10326, Republic of Korea. Electronic address: bubblem@dongguk.ac.kr.
AN  - 36463095
AU  - Lee,
AU  - J.
AU  - H.
AU  - Jo,
AU  - H.
AU  - G.
AU  - Min,
AU  - S.
AU  - Y.
DA  - Nov 24
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.explore.2022.11.002
DP  - Ovid Technologies
J2  - Explore (NY)
L1  - internal-pdf://1025070261/1-s2.0-S1550830722002063-main.cleaned.pdf
LA  - English
N1  - Using Smart Source ParsingNovLee, Ju HyunJo, Hee GeunMin, Sang YeonS1550-8307(22)00206-3
PY  - 2022
SP  - 24
T2  - Explore: The Journal of Science &amp; Healing
TI  - East asian herbal medicine for the treatment of children with attention deficit hyperactivity disorder: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36463095
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36463095&amp;id=doi:10.1016%2Fj.explore.2022.11.002&amp;issn=1550-8307&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2022&amp;title=Explore%3A+The+Journal+of+Science+%26+Healing&amp;atitle=East+asian+herbal+medicine+for+the+treatment+of+children+with+attention+deficit+hyperactivity+disorder%3A+A+Systematic+Review+and+Meta-analysis.&amp;aulast=Lee&amp;pid=%3Cauthor%3ELee+JH%3C%2Fauthor%3E%3CAN%3E36463095%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 24
ER  -
TY  - JOUR
AB  - **Objective:** 
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by developmentally inappropriate inattention, hyperactivity, and impulsivity. Multiple cognitive training appeared to be more effective than working memory training, but the evidence remains insufficient, particularly for the subgroup symptoms and executive function behaviors at home. Further analysis of the impact of factors on the effectiveness would facilitate the development of cognitive training.

**Methods:** 
We searched PubMed, Cochrane Library, Psyche, Embase, Chinese Biomedical Literature Database, CNKI, and Weifang Database, and included randomized controlled trials (RCTs) of children with ADHD undergoing cognitive intervention. Metaanalysis and univariate metaregression were performed by STATE. The risk of bias was assessed with the Cochrane risk of bias tool 2.0 by the two investigators separately. This study was registered with INPLASY, number INPLASY202140065.

**Results:** 
We included 17 RCTs in the systematic review, with a combined 1,075 participants. For metaanalyses of both subgroups of ADHD symptoms and the executive function behaviors, the test of published bias failed to reach the p &lt; 0.05 level. When all of the training are considered together, cognitive training can improve the presentation of inattention symptoms [SMD = -0.390, 95%CI (-0.675, -0.104)] and executive function behaviors (SMD = -0.319, 95%CI (-0.527, -0.111)]. In the subgroup analysis, the effects of working memory training on both presentations were not statistically significant. In contrast, the multiple cognitive training had significant effects on the presentation of inattention symptoms [SMD = -0.507, 95% CI (-0.722, -0.292)], hyperactivity/impulsivity [SMD = -0.305, 95% CI (-0.518, -0.09)], and the executive function behaviors [SMD = -0.499, 95%CI (-0.707, -0.290)]. In addition, metaregression analysis showed that only training frequency did significantly impact the symptoms of ADHD and the executive function behaviors.

**Conclusion:** 
This study showed that improvements in symptoms and executive function behaviors were related to the domains of cognitive intervention. The findings suggest that multiple domains of cognitive training and moderate training frequency may have wider clinical benefits. All the above results highlight further research in refining the executive functions of children with ADHD and developing individually tailored cognitive intervention on homes based for children with vulnerable executive functions.
AN  - WOS:000748135900001
AU  - Chen,
AU  - S.
AU  - X.
AU  - Yu,
AU  - J.
AU  - L.
AU  - Zhang,
AU  - Q.
AU  - Zhang,
AU  - J.
AU  - Zhang,
AU  - Y.
AU  - Wang,
AU  - J.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyg.2021.810298
L1  - internal-pdf://1177415667/Which Factor Is More Relevant to the Effe-2022.pdf
PY  - 2022
SP  - 10
T2  - Frontiers in Psychology
TI  - Which Factor Is More Relevant to the Effectiveness of the Cognitive Intervention? A Meta-Analysis of Randomized Controlled Trials of Cognitive Training on Symptoms and Executive Function Behaviors of Children With Attention Deficit Hyperactivity Disorder
UR  - &lt;Go to ISI&gt;://WOS:000748135900001
VL  - 12
ER  -
TY  - JOUR
AB  - **Objective:** 
To evaluate the efficacy of psychotherapy in children with tic disorder and to provide basis for the application of psychotherapy in the treatment of children with tic disorder. 

**Methods:** 
A detailed search was conducted based on PubMed, Cochrane library database, CNKI, Wanfang Data, and VIP database to determine the randomized controlled trial (RCT) of psychotherapy combined with drugs and oral drugs in the treatment of tic disorder. The search time was from the establishment of the database to August 20, 2021. All kinds of extracted data are meta analyzed, and the statistical software used is Review Manager 5.3 software. 

**Results:** 
According to the inclusion and exclusion criteria, 14 clinical trials were finally included, including 513 TD children, including 267 in the psychological intervention group and 246 in the control group. All trials were conducted in China and published from 2013 to 2021. In terms of clinical efficacy, compared with the control group, the psychotherapy combined with drugs group had more advantages in improving the effective rate (RR = 3.25, 95% CI: 2.17~4.85, Z = 5.74, P &lt; 0.00001) and improving the clinical symptoms of children with TD (WM = -5.36, 95% CI: -6.41 ~ -4.30, Z = 9.97, P &lt; 0.00000 1). 

**Conclusion:** 
Psychotherapy as an adjuvant therapy for clinical treatment of TD can improve the clinical efficacy, but due to the low methodological quality of the existing trials, the research may have potential bias. In the future, large sample, multicenter, and double-blind randomized controlled trials need to be carried out to provide further support.
AN  - 35419080
AU  - Kong,
AU  - Y.
AU  - Zhang,
AU  - X.
AU  - Ma,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1155/2022/2365210
L1  - internal-pdf://2816627927/Psychotherapy Combined with Western Medic-2022.pdf
PY  - 2022
SP  - 2365210
T2  - Computational &amp; Mathematical Methods in Medicine
TI  - Psychotherapy Combined with Western Medicine in the Treatment of Children with Tic Disorder: Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35419080
UR  - https://downloads.hindawi.com/journals/cmmm/2022/2365210.pdf
VL  - 2022
ER  -
TY  - JOUR
AB  - **Background**
Considering the rapid global movement towards inclusion for students with special educational needs (SEN), there is a surprising lack of pedagogical or didactic theories regarding the ways in which inclusive education may affect students with SEN. Group composition within the educational setting may play a role in determining the academic achievement, socio-emotional development, and wellbeing of students with SEN. Proponents of inclusion propose that segregated educational placement causes stigmatisation and social isolation which may have detrimental effects on the self-concept and self-confidence of students with SEN. On the other hand, opponents of inclusion for all special needs students suggest that placement in general education classrooms may have adverse effects especially if the time and resources allocated for individualisation are not aligned with student needs. Since the 1980s, a number of reviews on the effects of inclusion have been published. Results are inconsistent, and several reviews point to a number of methodological challenges and weaknesses of the study designs within primary studies. In sum, the impact of inclusion on students with SEN may be hypothesised to be both positive and negative, and the current knowledge base is inconsistent.

**Objectives**
The objective was first:To uncover and synthesise data from contemporary studies to assess the effects of inclusion on measures of academic achievement, socio-emotional development, and wellbeing of children with special needs when compared to children with special needs who receive special education in a segregated setting.A secondary objective was to explore how potential moderators (gender, age, type and severity of special need, part or full time inclusive education, and co-teaching) relate to outcomes.

**Search Methods**
Relevant studies were identified through electronic searches in Academic Search Premier (EBSCO), APA PsycINFO (EBSCO), EconLit (EBSCO), ERIC (EBSCO), International Bibliography of the Social Sciences (ProQuest), Sociological Abstracts (ProQuest), Science Citation Index Expanded (Web Of Science), Social Sciences Citation Index (Web Of Science), and SocINDEX (EBSCO). The database searches were completed on 24 April 2021 and other resources: grey literature repositories, hand search in targeted journals and Internet search engines were searched in August/September 2021. The search was limited to studies reported after 2000.

**Selection Criteria**
The review included studies of children with special needs in grades K to 12 in the OECD countries. Children with all types of verifiable SEN were eligible. Inclusion refers to an educational setting with a mixture of children with and without SEN. Segregation refers to the separate education of children with SEN. All studies that compared inclusive versus segregated educational settings for children with SEN were eligible. Qualitative studies were not included.

**Data Collection and Analysis**
The total number of potentially relevant studies constituted 20,183 hits. A total of 94 studies met the inclusion criteria, all were non-randomised studies. The 94 studies analysed data from 19 different countries. Only 15 studies could be used in the data synthesis. Seventy-nine studies could not be used in the data synthesis as they were judged to be of critical risk of bias and, in accordance with the protocol, were excluded from the meta-analysis on the basis that they would be more likely to mislead than inform. The 15 studies came from nine different countries. Separate meta-analyses were conducted on conceptually distinct outcomes. All analyses were inverse variance weighted using random effects statistical models. Sensitivity analyses were performed to evaluate the robustness of pooled effect sizes across components of risk of bias.

**Main Results**
The average baseline year of the interventions analysed in the 15 studies used for meta-analysis was 2006, ranging from 1998 to 2012. The average number of participants analysed in the interventions was 151, ranging from 10 to 1357, and the average number of controls was 261, ranging from 5 to 2752. The studies included children with multiple types of disabilities such as learning disorders/intellectual disabilities, autism spectrum disorders, ADHD, physical handicaps, visual impairments, and Down syndrome. At most, the results from eight studies could be pooled in any of the meta-analyses. All the meta-analyses showed a weighted average that favoured the intervention group. None of them were statistically significant. The random effects weighted standardised mean difference was 0.20 (95% confidence interval [CI]:
AU  - Dalgaard,
AU  - N.
AU  - T.
AU  - Bondebjerg,
AU  - A.
AU  - Viinholt,
AU  - B.
AU  - C.
AU  - A.
AU  - Filges,
AU  - T.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1002/cl2.1291
L1  - internal-pdf://1352363803/Campbell Systematic Reviews - 2022 - Dalgaard.pdf
PY  - 2022
T2  - Campbell Systematic Reviews
TI  - The effects of inclusion on academic achievement, socioemotional development and wellbeing of children with special educational needs
ER  -
TY  - JOUR
AB  - **Background**
Autism spectrum disorder (ASD; also known as autism) is a developmental disability that begins in childhood and is typically seen in around 1% to 2% of children. It is characterised by social communication difficulties and repetitive and restricted behaviours and routines that can have a negative impact on a child&#039;s quality of life, achievement at school, and social interactions with others. It has been hypothesised that memantine, which is traditionally used to treat dementia, may be effective in reducing the core symptoms of autism as well as some co‐occurring symptoms such as hyperactivity and language difficulties. If memantine is being used to treat the core symptoms of autism, it is important to review the evidence of its effectiveness.

**Objectives**
To assess the effects of memantine on the core symptoms of autism, including, but not limited to, social communication and stereotypical behaviours.

**Search methods**
We searched CENTRAL, MEDLINE, Embase, nine other databases and three trials registers up to February 2022. We also checked reference lists of key studies and checked with experts in the field for any additional papers. We searched for retractions of the included studies in MEDLINE, Embase, and the Retraction Watch Database. No retractions or corrections were found.

**Selection criteria**
We included randomised controlled trials (RCTs) of any dose of memantine compared with placebo in autistic people. We also included RCTs in which only one group received memantine, but both groups received the same additional therapy (e.g. a behaviour intervention).

**Data collection and analysis**
We used standard Cochrane methods. Our primary outcomes were core autism symptoms and adverse effects. Secondary outcomes were language, intelligence, memory, adaptive behaviour, hyperactivity, and irritability. We used GRADE to assess certainty of evidence. 

**Main results**
We included three RCTs (two double-blind and one single-blind) with 204 participants that examined the short-term effect (immediately postintervention) of memantine in autistic people. Two studies took place in the USA and the other in Iran. All three studies focused on children and adolescents, with a mean age of 9.40 (standard deviation (SD) 2.26) years. Most participants were male (range across studies 73% to 87%). The diagnosis of ASD was based on the Diagnostic and Statistical Manual of Mental Disorders (4th edition; 4th edition, textrevision; or 5th edition). To confirm the diagnosis, one study used the Autism Diagnostic Observation Schedule (ADOS) and the Autism Diagnostic Interview-Revised (ADI-R); one used ADOS, ADI-R or the Autism Diagnostic Interview Screener; and one used the Gilliam Autism Rating Scale. Dosage of memantine was based on the child&#039;s weight and ranged from 3 mg to 15 mg per day.

**Comparisons** 
Two studies examined memantine compared with placebo; in the other study, both groups had a behavioural intervention while only one group was given memantine.

**Risk of bias** 
All studies were rated at high risk of bias overall, as they were at high or unclear risk of bias across all but four domains in one study, and all but two domains in the other two studies. One study was funded by Forest Laboratories, LLC, (Jersey City, New Jersey), Allergan. The study sponsor was involved in the study design, data collection (via contracted clinical investigator sites), analysis and interpretation of data, and the decision to present these results. The other two studies reported no financial support or sponsorship; though in one of the two, the study medication was an in-kind contribution from Forest Pharmaceuticals.

**Primary outcomes** 
There was no clear evidence of a difference between memantine and placebo with respect to severity of core symptoms of autism, although we are very uncertain about the evidence. The standardised mean difference in autism symptoms score in the intervention group versus the control group was &ndash;0.74 standard deviations (95% confidence interval (CI) &minus;2.07 to 0.58; 2 studies, 181 participants; very low-certainty evidence; medium effect size); lower scores indicate less severe autistic symptoms. Two studies (144 participants) recorded adverse effects that the authors deemed related to the study and found there may be no difference between memantine and placebo (odds ratio (OR) 0.64, 95% CI 0.17 to 2.39; low-certainty evidence).

**Secondary outcomes** 
There may be no difference between memantine and placebo on language (2 studies, 144 participants; low-certainty evidence); memory or adaptive behaviour (1 study, 23 participants; both low-certainty evidence); or hyperactivity or irritability (1 study, 121 participants; both low-certainty evidence).

**Authors&#039; conclusions**
It is unclear whether memantine is an effective treatment for autistic children. None of the three included trials reported on the effectiveness of memantine in adults. Further studies using rigorous designs, larger samples, longer follow-up and clinically meaningful outcome measures that are important to autistic people and their families will strengthen our knowledge of the effects of memantine in autism.
AU  - Brignell,
AU  - A.
AU  - Marraffa,
AU  - C.
AU  - Williams,
AU  - K.
AU  - May,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013845.pub2
L1  - internal-pdf://0188928900/Brignell_et_al-2022-Cochrane_Database_of_Syste.pdf
PY  - 2022
T2  - Cochrane Database of Systematic Reviews
TI  - Memantine for autism spectrum disorder
ER  -
TY  - JOUR
AB  - The aim of this systematic review was to evaluate the effect of animal-assisted interventions on social functioning in children with autism spectrum disorder, based on evidence from randomized control trials. Included studies were articles published in English, with school aged children from 4 to 18 years with autism spectrum disorder. Databases searched were MEDLINE, PsycINFO, EMBASE, Web of Science, CINAHL and Zoological Record. Data extraction from included studies included demographics and sample features, interventions and controls descriptions, outcome measures, study funding and descriptive statistics. Risk of bias was assessed, considering randomization, allocation concealment, blinding, attrition, selective reporting and other sources of bias. Studies were synthesized narratively based on the animal approach taken and the use of waitlist versus active controls. Nine studies were included reporting across eight trials. Studies overall reported improvements in social functioning following equine-assisted services, with preliminary evidence suggesting improvements are sustained in the short and medium term. Insufficient evidence was available to draw conclusions on the efficacy of other animal-assisted interventions. Future research should aim to address the limitations common to included designs. Lay abstract Children with autism typically experience difficulties interacting socially with others when compared to their non-autistic peers. Establishing how effective interventions are for improving social functioning is important to help inform what should be offered to children with autism. This study reviewed how effective interventions that involved interaction with a live animal, known as animal-assisted interventions, are in improving social functioning in children with autism. A systematic search of the evidence on this topic found nine studies, which were explored for the effectiveness of animal-assisted interventions and the quality of methods used. Overall, these studies showed improvements in social functioning following equine-assisted or therapeutic horse-riding interventions, with initial evidence showing improvements are sustained in the short and medium term. However, several issues were identified, which limit the strength of any conclusions that can be drawn from this evidence. For example, in many studies people assessing the children were aware that they received the intervention or were in a control group. There was also not enough evidence available to draw conclusions on the effectiveness of other animal-assisted interventions. Future research should address the limitations that were common in the designs of these studies and investigate the potential benefit of other animal populations, such as dogs and cats.
AN  - WOS:000780799400001
AU  - Sissons,
AU  - J.
AU  - H.
AU  - Blakemore,
AU  - E.
AU  - Shafi,
AU  - H.
AU  - Skotny,
AU  - N.
AU  - Lloyd,
AU  - D.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/13623613221085338
L1  - internal-pdf://1007640703/Calm with horses_ A systematic review of anima.pdf
PY  - 2022
SP  - 21
T2  - Autism
TI  - Calm with horses? A systematic review of animal-assisted interventions for improving social functioning in children with autism
UR  - &lt;Go to ISI&gt;://WOS:000780799400001
ER  -
TY  - JOUR
AB  - This study conducts a systematic review and meta-analysis of the randomized-controlled clinical trials (RCTs) of attachment-and relationship-based interventions in the NICU. 

A systematic search of the PubMed, MEDLINE, Embase (OVID), PsycINFO, and CINAHL databases and the Cochrane Database of Systematic Reviews was conducted in February 2021. 

Of the 32,904 studies examined, 15 were identified as relevant, and 10 RCTs were eligible for meta-analysis. Cochrane&#039;s risk of bias tool was used to assess the quality of the trial reporting. Interventions were categorized as (1) parent-infant interactions, (2) parent education, and/or (3) support through qualitative synthesis. 

The attachment-or relationship-based intervention was effective in relieving maternal traumatic stress, maternal depression, infant weight growth, and infant development. Subgroup analyses suggested that interventions significantly improved sub-domains of mothers&#039; and children&#039;s interactive behavior. Tailored, staged interventions may contribute to better health outcomes in preterm infants and their families. Copyright &copy; 2022 by the authors. Licensee MDPI, Basel, Switzerland.
AN  - 2015349712
AU  - Kim,
AU  - S.
AU  - Y.
AU  - Kim,
AU  - A.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph19031126
L1  - internal-pdf://1723505691/Attachment-and Relationship-Based Interve-2022.pdf
PY  - 2022
T2  - International Journal of Environmental Research and Public Health
TI  - Attachment-and Relationship-Based Interventions during NICU Hospitalization for Families with Preterm/Low-Birth Weight Infants: A Systematic Review of RCT Data
UR  - https://www.mdpi.com/1660-4601/19/3/1126/pdf
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-19-01126/article_deploy/ijerph-19-01126.pdf
VL  - 19(3) (no pagination)
ER  -
TY  - JOUR
AB  - AIM: Cognitive behavioral treatment (CBT) and selective serotonin reuptake inhibitors (SSRIs) are considered first-line treatments for childhood anxiety disorders (ADs). The objective of this current analysis was to conduct a network meta-analysis to evaluate the comparative effectiveness of CBT, pharmacotherapy, and the combination of the two in treating pediatric ADs. 

METHODS: The studies included consisted of randomized controlled trials evaluating non-selective serotonin reuptake inhibitors (e.g. clomipramine), SSRIs, selective noradrenaline reuptake inhibitors, CBT, or a combination of CBT and pharmacotherapy. Studies were eligible for inclusion if participants were 18 years or younger. 

RESULTS: A total of 86 studies were included, with a total of 7594 participants, of which 41.51% were females. For remission, all three treatments were significantly more effective than both placebo (ORs ranging from 0.07 and 0.18) and wait-list (ORs ranging from 0.06 and 0.16). In terms of the severity of anxiety symptoms, all treatment forms were significantly more effective for reducing anxiety than wait-list (standardized mean differences (SMDs) ranging from 0.98 and 2.91). Only pharmacotherapy was significantly more effective in reducing anxiety symptoms than placebo (SMD = 2.01, 95% confidence interval, 1.02 to 3.01). Overall, the results demonstrate that CBT, pharmacotherapy, and their combination are effective treatments for childhood ADs. There was no significant difference between the three treatment forms. However, CBT was associated with lower attrition rates. 

CONCLUSION: CBT, pharmacotherapy, and the combination of the two should all be considered to treat youths with ADs. However, potential risks and benefits should be considered before devising a treatment plan.
AN  - 35507829
AU  - Arnardottir,
AU  - A.
AU  - Skarphedinsson,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/08039488.2022.2069858
L1  - internal-pdf://1492126457/Arnardottir-2022.pdf
PY  - 2022
SP  - 1-9
T2  - Nordic Journal of Psychiatry
TI  - Comparative effectiveness of cognitive behavioral treatment, serotonin, and serotonin noradrenaline reuptake inhibitors for anxiety in children and adolescents: a network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35507829
UR  - https://www.tandfonline.com/doi/full/10.1080/08039488.2022.2069858
ER  -
TY  - JOUR
AB  - **Background** 
There is still no approved medication for the core symptoms of autism spectrum disorder (ASD). This network meta-analysis investigated pharmacological and dietary-supplement treatments for ASD. 

**Methods** 
We searched for randomized-controlled-trials (RCTs) with a minimum duration of seven days in ClinicalTrials.gov, EMBASE, MEDLINE, PsycINFO, WHO-ICTRP (from inception up to July 8, 2018), CENTRAL and PubMed (up to November 3, 2021). The co-primary outcomes were core symptoms (social-communication difficulties-SCD, repetitive behaviors-RB, overall core symptoms-OCS) measured by validated scales and standardized-mean-differences (SMDs). Associated symptoms, e.g., irritability/aggression and attention-deficit/hyperactivity disorder (ADHD) symptoms, dropouts and important side-effects, were investigated as secondary outcomes. Studies in children/adolescents and adults were analyzed separately in random-effects pairwise and network meta-analyses. 

**Results** 
We analyzed data for 41 drugs and 17 dietary-supplements, from 125 RCTs (n = 7450 participants) in children/adolescents and 18 RCTs (n = 1104) in adults. The following medications could improve at least one core symptom domain in comparison with placebo: aripiprazole (k = 6 studies in analysis, SCD: SMD = 0.27 95% CI [0.09, 0.44], RB: 0.48 [0.26, 0.70]), atomoxetine (k = 3, RB:0.49 [0.18, 0.80]), bumetanide (k = 4, RB: 0.35 [0.09, 0.62], OCS: 0.61 [0.31, 0.91]), and risperidone (k = 4, SCM: 0.31 [0.06, 0.55], RB: 0.60 [0.29, 0.90]; k = 3, OCS: 1.18 [0.75, 1.61]) in children/adolescents; fluoxetine (k = 1, RB: 1.20 [0.45, 1.96]), fluvoxamine (k = 1, RB: 1.04 [0.27, 1.81]), oxytocin (k = 6, RB:0.41 [0.16, 0.66]) and risperidone (k = 1, RB: 0.97 [0.21,1.74]) in adults. There were some indications of improvement by carnosine, haloperidol, folinic acid, guanfacine, omega-3-fatty-acids, probiotics, sulforaphane, tideglusib and valproate, yet imprecise and not robust. Confidence in these estimates was very low or low, except moderate for oxytocin. Medications differed substantially in improving associated symptoms, and in their side-effect profiles. 

**Limitations** 
Most of the studies were inadequately powered (sample sizes of 20-80 participants), with short duration (8-13 weeks), and about a third focused on associated symptoms. Networks were mainly star-shaped, and there were indications of reporting bias. There was no optimal rating scale measuring change in core symptoms. 

**Conclusions** 
Some medications could improve core symptoms, although this could be likely secondary to the improvement of associated symptoms. Evidence on their efficacy and safety is preliminary; therefore, routine prescription of medications for the core symptoms cannot be recommended. Trial registration PROSPERO-ID CRD42019125317.
AN  - WOS:000764718300001
AU  - Siafis,
AU  - S.
AU  - Ciray,
AU  - O.
AU  - Wu,
AU  - H.
AU  - Schneider-Thoma,
AU  - J.
AU  - Bighelli,
AU  - I.
AU  - Krause,
AU  - M.
AU  - Rodolico,
AU  - A.
AU  - Ceraso,
AU  - A.
AU  - Deste,
AU  - G.
AU  - Huhn,
AU  - M.
AU  - Fraguas,
AU  - D.
AU  - Caceres,
AU  - A.
AU  - S.
AU  - Mavridis,
AU  - D.
AU  - Charman,
AU  - T.
AU  - Murphy,
AU  - D.
AU  - G.
AU  - Parellada,
AU  - M.
AU  - Arango,
AU  - C.
AU  - Leucht,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1186/s13229-022-00488-4
L1  - internal-pdf://2121106794/Pharmacological and dietary-supplement tr-2022.pdf
PY  - 2022
SP  - 17
T2  - Molecular Autism
TI  - Pharmacological and dietary-supplement treatments for autism spectrum disorder: a systematic review and network meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000764718300001
UR  - https://molecularautism.biomedcentral.com/track/pdf/10.1186/s13229-022-00488-4.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - Bullying and cyberbullying bring adverse physical and psychological impacts on individuals and an economic burden for society. Scholars have developed anti-bullying intervention programs to combat these problems. This meta-analysis aims to examine and compare the effectiveness of digital health interventions (DHIs) in reducing bullying and cyberbullying. A comprehensive search was conducted using databases (PsycINFO, Social Service Abstracts, Sociological Abstracts, MEDLINE, ERIC, and EMBASE). Quasi-experimental and randomized controlled trials (RCTs) published before 31 January 2021 that reported the effects of DHIs in reducing bullying or cyberbullying were included. The 16 studies included in the synthesis reported overall random effect sizes (Cohen&#039;s d) for bullying and cyberbullying reduction were 0.41 and 0.19, respectively. The results provide evidence on the effectiveness of DHIs, comparable to that of face-to-face interventions. The subgroup analysis revealed that the critical components of effective DHIs include training on bystander and bully-victim dual roles, coping skills, and interactive serious games. It highlights the promising effects of digital health approaches in bullying and cyberbullying interventions. Our review identifies avenues for future research on the development of more effective DHIs to reduce bullying and cyberbullying.
AN  - WOS:000787253800001
AU  - Chen,
AU  - Q.
AU  - Q.
AU  - Chan,
AU  - K.
AU  - L.
AU  - Guo,
AU  - S.
AU  - Y.
AU  - Chen,
AU  - M.
AU  - T.
AU  - Lo,
AU  - C.
AU  - K.
AU  - M.
AU  - Ip,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/15248380221082090
L1  - internal-pdf://3972666385/Effectiveness of Digital Health Interventions.pdf
PY  - 2022
SP  - 17
T2  - Trauma Violence &amp; Abuse
TI  - Effectiveness of Digital Health Interventions in Reducing Bullying and Cyberbullying: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000787253800001
UR  - https://journals.sagepub.com/doi/pdf/10.1177/15248380221082090
ER  -
TY  - JOUR
AB  - **Importance:** 
Sexual violence is a public health problem that affects adolescents globally. To our knowledge, no meta-analysis of prevention programs for adolescent sexual violence has been conducted. 

**Objective:** 
To perform a systematic review and meta-analysis of randomized clinical trials evaluating the efficacy of psychosocial programs for preventing sexual violence during adolescence. 

**Data Sources:**
Peer-reviewed articles published in English were searched in PsycINFO, ERIC, PsycArticles, PubMed, and Web of Science databases through December 2021. 

**Study Selection:** 
Studies were included if they were randomized clinical trials assessing the efficacy of a psychosocial prevention program targeting sexual violence and delivered to adolescents aged 10 to 19 years. 

**Data Extraction and Synthesis:** 
Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines were followed to identify studies. The quality of individual studies was assessed with the Revised Cochrane Collaboration Risk of Bias tool. A random-effects model was used to pool odds ratios (ORs). Exploratory subgroup and metaregression analyses were performed to evaluate the associations between moderators and effect sizes. 

**Main Outcomes and Measures:** 
Primary outcomes were perpetration of sexual violence, experience of sexual violence, and a composite measure of any perpetration or experience of sexual violence. Results: Data were analyzed from 20 trials involving 37294 adolescents. Compared with control conditions, prevention programs were associated with a significant reduction in the perpetration (OR, 0.83; 95% CI, 0.73-0.95; P = .005) and experience (OR, 0.87; 95% CI, 0.78-0.98; P = .02) of sexual violence, as well as a 13% significant reduction of any sexual violence (OR, 0.87; 95% CI, 0.78-0.97; P = .009). Exploratory analyses of the combination of program setting and participant age indicated that programs that were delivered in school settings and targeted at adolescents aged 15 to 19 years yielded significantly larger effect sizes (Cochran Q = 4.8; P = .03) compared with programs that were either delivered outside of a school setting or targeted younger adolescents. Quality assessment of trials revealed concerns of risk of bias across several included studies.

**Conclusions and Relevance:** 
In this meta-analysis, evidence suggested that prevention programs were associated with reducing adolescent sexual violence, especially when implemented at school with older adolescents. However, there is need for additional high-quality research. Prevention of adolescent sexual violence remains understudied compared with other similarly important public health prevention targets.
AN  - 36346627
AU  - Piolanti,
AU  - A.
AU  - Jouriles,
AU  - E.
AU  - N.
AU  - Foran,
AU  - H.
AU  - M.
DB  - Alerts 6_2022.enl
DO  - /10.1001/jamanetworkopen.2022.40895
L1  - internal-pdf://0826463912/Piolanti-2022-Assessment of Psychosocial Progr.pdf
PY  - 2022
SP  - e2240895
T2  - JAMA Network Open
TI  - Assessment of Psychosocial Programs to Prevent Sexual Violence During Adolescence: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36346627
UR  - https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2798204/piolanti_2022_oi_221159_1666975780.57092.pdf
VL  - 5
ER  -
TY  - JOUR
AB  - Attachment- and emotion-focused parenting interventions (AE) have grown in popularity as an alternative to behavioral parent training (BPT) for children and adolescents. AE go beneath behavior by helping parents understand and respond to their child&#039;s underlying attachment and emotional needs. Past reviews have examined their effects on attachment security and caregiver sensitivity, though less is known regarding their effects on child mental health symptoms. Reported here is the first systematic review and meta-analysis of individual and group AE on externalizing behavior (EXT) and internalizing behavior (INT) for children aged 0-18 years.

 A search of four databases prior to July 2021 elicited 43 studies that met eligibility criteria. Meta-analysis revealed that AE were superior to waitlist controls for EXT (SMD = - 0.17) and INT (SMD = - 0.34). Effects were sustained at follow-up periods of 6 months and greater, and AE considered to target child mental health were significantly more effective than those that did not in reducing EXT and INT. Two studies retrieved directly compared AE to BPT, which showed no evidence of a difference for follow-up measures of EXT. No studies compared AE to BPT on INT. AE demonstrated no evidence of superiority compared to controls for parent mental health. 

Findings support the potential for AE to reduce EXT and INT in children and adolescents; however, future research should consider the relative effectiveness of AE.
AN  - 35680711
AU  - Jugovac,
AU  - S.
AU  - O&#039;Kearney,
AU  - R.
AU  - Hawes,
AU  - D.
AU  - J.
AU  - Pasalich,
AU  - D.
AU  - S.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s10567-022-00401-8
L1  - internal-pdf://4115974092/Jugovac-2022-Attachment- and Emotion-Focused P.pdf
PY  - 2022
SP  - 10
T2  - Clinical Child &amp; Family Psychology Review
TI  - Attachment- and Emotion-Focused Parenting Interventions for Child and Adolescent Externalizing and Internalizing Behaviors: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35680711
UR  - https://link.springer.com/content/pdf/10.1007/s10567-022-00401-8.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - OBJECTIVES: We assessed the effect of feeding preterm or low birth weight infants with infant formula compared with mother&#039;s own milk on mortality, morbidity, growth, neurodevelopment, and disability. 

METHODS: We searched Medline (Ovid), Embase (Ovid), and Cochrane Central Register of Controlled Studies to October 1, 2021. 

RESULTS: Forty-two studies enrolling 89 638 infants fulfilled the inclusion criteria. We did not find evidence of an effect on mortality (odds ratio [OR] 1.26, 95% confidence interval [CI] 0.91-1.76), infection (OR 1.52, 95% CI 0.98-2.37), cognitive neurodevelopment (standardized mean difference -1.30, 95% CI -3.53 to 0.93), or on growth parameters. Formula milk feeding increased the risk of necrotizing enterocolitis (OR 2.99, 95% CI 1.75-5.11). The Grading of Recommendations Assessment, Development, and Evaluation certainty of evidence was low for mortality and necrotizing enterocolitis, and very low for neurodevelopment and growth outcomes. 

CONCLUSIONS: In preterm and low birth weight infants, low to very low-certainty evidence indicates that feeding with infant formula compared with mother&#039;s own milk has little effect on all-cause mortality, infection, growth, or neurodevelopment, and a higher risk of developing necrotizing enterocolitis.
AN  - 35921674
AU  - Strobel,
AU  - N.
AU  - A.
AU  - Adams,
AU  - C.
AU  - McAullay,
AU  - D.
AU  - R.
AU  - Edmond,
AU  - K.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1542/peds.2022-057092D
L1  - internal-pdf://3416886031/Strobel-2022-Mother&#039;s Own Milk Compared With F.pdf
PY  - 2022
SP  - 01
T2  - Pediatrics
TI  - Mother&#039;s Own Milk Compared With Formula Milk for Feeding Preterm or Low Birth Weight Infants: Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35921674
UR  - https://watermark.silverchair.com/peds_2022057092d.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAvEwggLtBgkqhkiG9w0BBwagggLeMIIC2gIBADCCAtMGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM59ZV6_E1aLqy4o18AgEQgIICpNGJQAsTXW4_I1JlfIRyNT00PPLAniY_B2a359s3ih7XejcZwwiA54vlUIA_gOJ20tEI4G0kGyxJ3sWQsIoZvwJGewpudlqHAnpRIS44tDG2MVRNjycNoecN9tWQHudn2LTJ8CnhOLNpGIFUKgtnbQ9XHE4_Huva-dUuESOcuMQ0g3k5ix8Y1K-3L9nBjcJvHPV4lmHLT5UVLU09HGw8fH2wHjFZLxCtAIVTuVsDMM9axsJB909M9AKIBH3rAOtL6B4Ef605U3BY4PNFSa7FoBbHxd5j0UR0mGgjZEYbIGWG6p7aGSlaLu5fuaJBq4rgDg0U2wZYouMEHRBq7TE-dXC7xZjtMR8yLzcNEKp-cKQRnw0Y04LAiWios-XPd8Ob3EobzqBMi8psHmqr_0uMZ3dIVR-N88c-VaKuCagjy2xWVGA1XoAuwzuvbt7Dr2FRze3IFiNUYrytDgdHQQwvcWbIMEI1HLQoq8lSUyx2CTomQlPDrOh0cA7x0lCjhYw8Fuw_6loZN4pCDtEIYCzlCkZfp4jL4gBq13Z6joKEL8pIchnYx0an4qtrd05CiXxqM47JJySE6QYh-V7cvv4_UIkX2qZyeMJLUrgMKf7NsoUmVAxgkLfJTk3FqcfFbXL0bw-2ZQRnVZfcXleSaJDBa-fZ5bFoXI5ZmlWKYzxpS2I_mz7F6PsY3-eG-vs_8IS9dQAtBiCOsm5Es68Tmbt3dy5LgVhgY_1Eb5tVyNNSCFO6h16iy4vnALadEmKCwnhujblwKieV63irHbdkKFFx9KEAcMUcLjwa3uZ0iKNeK3Lvj-JvcpXtdSlWU0PnX8KQiBMhpJ7PuwLsV8ZsfUDWrec390xsh1JTVWsV8eyDmmxwGE5Kx3KPWp9zrgEMy244Jq4jp5Q
VL  - 150
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) is a prevalent and serious disorder among children. Video games have shown potential for aiding in child healthcare. Video games could contribute to the assessment and management of ADHD, but there are no previous reviews on this topic. Here, we systematically review the evidence about video game-based assessment tools and interventions for children diagnosed with ADHD. This review followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The review protocol was registered in PROSPERO database. We searched four databases-PubMed, PsycInfo, Embase and clinicaltrials.gov-to identify original studies exploring either video game-based interventions or video game-based assessment tools in children with ADHD. After initial screening, full text revision and study selection, 22 articles were finally included in the review. Most studies used PC as platform, with a minority using a video console, pad, or 3D device. Video game-based assessment tools were generally effective in discriminating ADHD cases from controls, and in discriminating between ADHD subtypes. Video game-based therapeutic interventions were well accepted and generally effective in improving cognitive areas and decreasing ADHD symptoms. Gamification and cognitive training could be the main mechanisms underlying the usefulness and effectiveness of video game-based assessment tools and interventions. Software optimization and greater collaboration between developers and healthcare professionals are some of the priorities for future research in this area.
AN  - 32424511
AU  - Penuelas-Calvo,
AU  - I.
AU  - Jiang-Lin,
AU  - L.
AU  - K.
AU  - Girela-Serrano,
AU  - B.
AU  - Delgado-Gomez,
AU  - D.
AU  - Navarro-Jimenez,
AU  - R.
AU  - Baca-Garcia,
AU  - E.
AU  - Porras-Segovia,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-020-01557-w
L1  - internal-pdf://2235435117/Video games for the assessment and treatm-2022.pdf
PY  - 2022
SP  - 5-20
T2  - European Child &amp; Adolescent Psychiatry
TI  - Video games for the assessment and treatment of attention-deficit/hyperactivity disorder: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=32424511
UR  - https://link.springer.com/content/pdf/10.1007/s00787-020-01557-w.pdf
VL  - 31
ER  -
TY  - JOUR
AB  - AIM: To appraise the current evidence on the efficacy and safety of lamotrigine (LAM) in the treatment of pediatric mood disorders (PMD) (i.e., Major Depressive disorder [MDD], bipolar disorder [BD]). 

METHODS: Major databases were searched for randomized controlled trials (RCTs), open-label trials, and observational studies reporting on pediatric (age &lt; 18 years) patients treated with LAM for mood disorders. 

RESULTS: A total of 3061 abstracts were screened and seven articles were selected for inclusion. Seven studies (319 BD and 43 MDD patients), including one RCT (n = 173), three prospective (n = 105), and three retrospective (n = 84) studies, met the study criteria with a study duration range from 8 to 60.9 weeks. The mean age of this pooled data is 14.6 +/- 2.0 years. LAM daily dosage varied from 12.5 to 391.3 mg/day among the studies. In an important finding, the RCT reported favorable outcomes with LAM (HR = 0.46; p = 0.02) in 13- to 17-year-old age group as compared with 10- to 12-year-old age group (HR = 0.93; p = 0.88). In addition, time to occurrence of a bipolar event trended toward favoring LAM over placebo. All the studies identified LAM as an effective and safe drug in PMDs especially, BDs. Overall, LAM was well tolerated with no major significant side effects and no cases of Stevens-Johnson syndrome. 

CONCLUSIONS: Most studies suggested that LAM was safe and effective in pediatric patients with mood disorders. However, the data regarding the therapeutic range for LAM are lacking. Based on the data, there is inconsistent evidence to make conclusive recommendations on therapeutic LAM dosage for mood improvement in the pediatric population. Further studies including larger sample sizes are required to address this relevant clinical question.
AN  - 36086813
AU  - Kumar,
AU  - R.
AU  - Garzon,
AU  - J.
AU  - Yuruk,
AU  - D.
AU  - Hassett,
AU  - L.
AU  - C.
AU  - Saliba,
AU  - M.
AU  - Ozger,
AU  - C.
AU  - Oztosun,
AU  - C.
AU  - Ahern,
AU  - K.
AU  - Athreya,
AU  - A.
AU  - P.
AU  - Singh,
AU  - B.
AU  - Croarkin,
AU  - P.
AU  - E.
AU  - Vande
AU  - Voort,
AU  - J.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/acps.13500
L1  - internal-pdf://1409467589/Kumar-2022-Efficacy and safety of lamotrigine.pdf
PY  - 2022
SP  - 09
T2  - Acta Psychiatrica Scandinavica
TI  - Efficacy and safety of lamotrigine in pediatric mood disorders: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36086813
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acps.13500?download=true
VL  - 09
ER  -
TY  - JOUR
AB  - **Objective:** 
To evaluate the effects of Tuina (massage) vs. non-Tuina traditional Chinese medicine (TCM) treatments on nocturnal enuresis in children. 

**Methods:** 
A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted following the Preferred Reported Items for Systematic Review and Meta-analysis (PRISMA) guidelines. RevMan 5.3 software was used for meta-analysis. 

**Results:** 
Twelve RCTs recruiting a total of 1,007 children were included. Meta-analysis results showed that, compared with non-Tuina TCM treatments, Tuina could significantly improve the total effective rate of children&#039;s enuresis [RR = 1.29, 95%CI (1.22-1.36), P &lt; 0.00001]. The results of subgroup analyses indicated that the total effective rate of Tuina combined with acupuncture in the treatment of nocturnal enuresis was higher than acupuncture alone [RR = 1.24, 95%CI (1.12-1.37), P &lt; 0.0001]. The total effective rate of Tuina in the treatment of enuresis in children was better than that of herbal medicine alone [RR = 1.45, 95%CI (1.31-1.61), P &lt; 0.00001]. The total effective rate of Tuina combined with herbal medicine in the treatment of enuresis in children was better than that of herbal medicine alone [RR = 1.16, 95%CI (1.06-1.26), P = 0.0007]. No adverse reactions of Tuina were reported in all included studies. 

**Conclusion:** 
From the available evidence, Tuina, or Tuina combined with non-Tuina TCM treatments (acupuncture, or herbal medicine) can improve the clinical outcome of children with enuresis, indicating Tuina is a promising treatment choice for children&#039;s enuresis. However, because of the intrinsic limitations of the included studies, more high-quality randomized controlled trials with longer follow-up are still needed to further confirm the efficacy and safety of Tuina in the treatment of nocturnal enuresis in children.
AN  - 35493365
AU  - Tong,
AU  - C.
AU  - He,
AU  - Q.
AU  - Ho,
AU  - M.
AU  - Zhong,
AU  - Z.
AU  - Wu,
AU  - Q.
AU  - Chen,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpubh.2022.821781
L1  - internal-pdf://3733995382/Tuina for Enuresis in Children_ A Systema-2022.pdf
PY  - 2022
SP  - 821781
T2  - Frontiers in Public Health
TI  - Tuina for Enuresis in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35493365
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039245/pdf/fpubh-10-821781.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **BACKGROUND**
The efficacy of surface electroencephalographic neurofeedback (EEG-NF) for improving attentional performance assessed by laboratory measures in patients with attention-deficit/hyperactivity disorder (ADHD) remains unclear.

**METHODS**
Following the PRISMA guidelines, the PubMed, Embase, ClinicalKey, Cochrane CENTRAL, ScienceDirect, Web of Science, and ClinicalTrials.gov databases were systematically searched for randomized controlled trials on the efficacy of surface EEG-NF against ADHD focusing on attentional performance evaluated by laboratory measures from inception to January 2022.

**RESULTS**
Fourteen eligible studies were analyzed. Of the 718 participants involved, 429 diagnosed with ADHD received EEG-NF treatment. Significant improvement in attentional performance in ADHD subjects receiving EEG-NF was noted compared to their comparators (p &lt; 0.01). Besides, there was a significant EEG-NF-associated beneficial effect on sustained attention (Hedges&#039; g = 0.32, p &lt; 0.01), whereas the impact on selective attention (p = 0.57) and working memory (p = 0.59) was limited. Moreover, protocol including beta wave enhancement was superior to that only focusing on reducing theta/beta ratio or modulation of slow cortical potential. Subgroup analyses showed that three sessions per week of EEG-NF produced the best effect, while the efficacy of surface EEG-NF was much poorer (Hedges&#039; g = 0.05) when only studies that blinded their participants from knowledge of treatment allocation were included. No significant difference was noted in the improvement of attentional performance 6-12 months after EEG-NF intervention (n = 3, p = 0.42).

**CONCLUSIONS**
Our results demonstrated the satisfactory effectiveness of surface EEG-NF for improving sustained attention, especially when beta wave enhancement was included, despite its failure to sustain a long-term effect. Further large-scale trials are warranted to support our findings.
AD  - Chiu, Hsien-Jane. Taoyuan Psychiatric Center, Ministry of Health and Welfare, Taoyuan, Taiwan.Chiu, Hsien-Jane. Institute of Hospital and Health Care Administration, National Yang Ming Chiao Tung University, Taipei, Taiwan.Sun, Cheuk-Kwan. Department of Emergency Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.Sun, Cheuk-Kwan. School of Medicine for International Students, College of Medicine, I-Shou University, Kaohsiung, Taiwan.Fan, Hsin-Yi. Department of Psychiatry, Tsyr-Huey Mental Hospital, Kaohsiung Jen-Ai&#039;s Home, No. 509, Fengping 1St Rd., Daliao Dist, Kaohsiung, Taiwan.Tzang, Ruu-Fen. Department of Psychiatry, Mackay Memorial Hospital, Taipei, Taiwan.Wang, Ming-Yu. Department of Psychiatry, China Medical University Hsinchu Hospital, China Medical University, Hsinchu, Taiwan.Wang, Ming-Yu. Department of Health Services Administration, China Medical University, Taichung, Taiwan.Cheng, Ying-Chih. Department of Psychiatry, China Medical University Hsinchu Hospital, China Medical University, Hsinchu, Taiwan.Cheng, Ying-Chih. Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan.Cheng, Ying-Chih. Research Center of Big Data and Meta-Analysis, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.Cheng, Yu-Shian. Department of Psychiatry, Tsyr-Huey Mental Hospital, Kaohsiung Jen-Ai&#039;s Home, No. 509, Fengping 1St Rd., Daliao Dist, Kaohsiung, Taiwan. n043283@gmail.com.Yeh, Pin-Yang. Department of Psychology, College of Medical and Health Science, Asia University, 500, Lioufeng Rd., Wufeng, Taichung, 41354, Taiwan. PsyYPY@asia.edu.tw.Chung, Weilun. Department of Psychiatry, Tsyr-Huey Mental Hospital, Kaohsiung Jen-Ai&#039;s Home, No. 509, Fengping 1St Rd., Daliao Dist, Kaohsiung, Taiwan. johnwayroom@gmail.com.
AN  - 36536438
AU  - Chiu,
AU  - H.
AU  - J.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Fan,
AU  - H.
AU  - Y.
AU  - Tzang,
AU  - R.
AU  - F.
AU  - Wang,
AU  - M.
AU  - Y.
AU  - Cheng,
AU  - Y.
AU  - C.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Yeh,
AU  - P.
AU  - Y.
AU  - Chung,
AU  - W.
DA  - Dec 19
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1186/s13034-022-00543-1
DP  - Ovid Technologies
J2  - Child Adolesc Psychiatry Ment Health
L1  - internal-pdf://0675565632/Chiu-2022-Surface electroencephalographic neur.pdf
LA  - English
N1  - Chiu, Hsien-JaneSun, Cheuk-KwanFan, Hsin-YiTzang, Ruu-FenWang, Ming-YuCheng, Ying-ChihCheng, Yu-ShianYeh, Pin-YangChung, Weilun
PY  - 2022
SP  - 104
T2  - Child &amp; Adolescent Psychiatry &amp; Mental Health [Electronic Resource]
TI  - Surface electroencephalographic neurofeedback improves sustained attention in ADHD: a meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36536438
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36536438&amp;id=doi:10.1186%2Fs13034-022-00543-1&amp;issn=1753-2000&amp;isbn=&amp;volume=16&amp;issue=1&amp;spage=104&amp;pages=104&amp;date=2022&amp;title=Child+%26+Adolescent+Psychiatry+%26+Mental+Health+%5BElectronic+Resource%5D&amp;atitle=Surface+electroencephalographic+neurofeedback+improves+sustained+attention+in+ADHD%3A+a+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Chiu&amp;pid=%3Cauthor%3EChiu+HJ%3C%2Fauthor%3E%3CAN%3E36536438%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://capmh.biomedcentral.com/counter/pdf/10.1186/s13034-022-00543-1.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - **Introduction**
The wide range of psychosocial interventions designed to assist people with Autism Spectrum Disorder (ASD) makes it challenging to compile and hierarchize the scientific evidence that supports the efficacy of these interventions. Thus, we performed an umbrella review of published meta-analyses of controlled clinical trials that investigated the efficacy of psychosocial interventions on both core and related ASD symptoms.

**Methods**
Each meta-analysis that was identified was re-estimated using a random-effects model with a restricted maximum likelihood estimator. The methodological quality of included meta-analyses was critically appraised and the credibility of the evidence was assessed algorithmically according to criteria adapted for the purpose of this study.

**Results**
We identified a total of 128 meta-analyses derived from 44 reports. More than half of the non-overlapping meta-analyses were nominally statistically significant and/or displayed a moderate-to-large pooled effect size that favored the psychosocial interventions. The assessment of the credibility of evidence pointed out that the efficacy of early intensive behavioral interventions, developmental interventions, naturalistic developmental behavioral interventions, and parent-mediated interventions was supported by suggestive evidence on at least one outcome in preschool children. Possible outcomes included social communication deficits, global cognitive abilities, and adaptive behaviors. Results also revealed highly suggestive indications that parent-mediated interventions improved disruptive behaviors in early school-aged children. The efficacy of social skills groups was supported by suggestive evidence for improving social communication deficits and overall ASD symptoms in school-aged children and adolescents. Only four meta-analyses had a statistically significant pooled effect size in a sensitivity analysis restricted to randomized controlled trials at low risk of detection bias.

**Discussion**
This umbrella review confirmed that several psychosocial interventions show promise for improving symptoms related to ASD at different stages of life. However, additional well-designed randomized controlled trials are still required to produce a clearer picture of the efficacy of these interventions. To facilitate the dissemination of scientific knowledge about psychosocial interventions for individuals with ASD, we built an open-access and interactive website that shares the information collected and the results generated during this umbrella review. Pre-registrationPROSPERO ID CRD42020212630. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-79956-001
AU  - Gosling,
AU  - C.
AU  - J.
AU  - Cartigny,
AU  - A.
AU  - Mellier,
AU  - B.
AU  - C.
AU  - Solanes,
AU  - A.
AU  - Radua,
AU  - J.
AU  - Delorme,
AU  - R.
DB  - Alerts 6_2022.enl
DO  - /10.1038/s41380-022-01670-z
L1  - internal-pdf://1349108333/Gosling-2022-Efficacy of psychosocial interven.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Molecular Psychiatry
TI  - Efficacy of psychosocial interventions for autism spectrum disorder: An umbrella review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-79956-001
UR  - https://www.nature.com/articles/s41380-022-01670-z
UR  - https://www.nature.com/articles/s41380-022-01670-z.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Several treatment options have been proposed for pediatric acute-onset neuropsychiatric syndrome/pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection (PANS/PANDAS). Still, no clear therapeutic protocol has been recognized to prevent these neuropsychiatric diseases. The study aims to report on the literature evidence and different treatment strategies related to these disorders. 

METHODS: 
We analyzed the last 20 years&#039; English language literature and performed a comprehensive review of the PANS/PANDAS treatment, including studies reporting OCD outcomes post-treatment follow-up. 

RESULTS: 
We covered 11 articles in our systematic literature review for a total of 473 patients, of which four studies included 129 surgical subjects and seven papers with 326 medically treated patients. Pooled outcomes analysis, surgical and medical treatment reported an OCD reduction, but no statistical significance was obtained (p &lt; 0.05 for both). 

CONCLUSIONS: 
Surgical therapy in selected patients can lead to promising results, although further evidence is needed. On the other hand, the role of medical therapy remains controversial, often due to the lack of univocal curative protocols and variable responses depending on the drug used and the timing of administration. Therefore, further investigations are necessary to clarify the most appropriate therapeutic procedure.
AN  - 35204876
AU  - Cocuzza,
AU  - S.
AU  - Maniaci,
AU  - A.
AU  - La
AU  - Mantia,
AU  - I.
AU  - Nocera,
AU  - F.
AU  - Caruso,
AU  - D.
AU  - Caruso,
AU  - S.
AU  - Iannella,
AU  - G.
AU  - Vicini,
AU  - C.
AU  - Privitera,
AU  - E.
AU  - Lechien,
AU  - J.
AU  - R.
AU  - Pavone,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/children9020155
L1  - internal-pdf://4292932025/Obsessive-Compulsive Disorder in PANS_PAN-2022.pdf
PY  - 2022
SP  - 26
T2  - Children
TI  - Obsessive-Compulsive Disorder in PANS/PANDAS in Children: In Search of a Qualified Treatment-A Systematic Review and Metanalysis
UR  - https://doi.org/10.3390/children9020155
VL  - 9
ER  -
TY  - JOUR
AB  - Objectives: This study was to investigated the efficacy of music therapy (MT) in children with autism spectrum disorder (ASD) via a meta-analysis that comprehensively evaluated data from all eligible research in this field. 

Design(s): Systematic review and meta-analysis. 

Setting(s): A systematic search of the PubMed, Embase, and Cochrane Library databases from inception to October 2021 to identify studies that administered MT to children with ASD. 

Result(s): Eight randomized controlled trials (RCTs) including 608 participants met the inclusion criteria. The meta-analysis showed that MT was associated with a significant increase in social reactions among children with ASD (standardized mean difference (SMD) = 0.24, 95% confidence interval (CI) [0.03, 0.46], I&lt;sup&gt;2&lt;/sup&gt; = 0%, P = 0.03). However, MT did not elicit a significant increase in symptom severity (SMD = 0.17, 95% CI [-0.04,0.38], I&lt;sup&gt;2&lt;/sup&gt; = 0%,P = 0.12), social adaptive behavior (SMD = 0.02, 95% CI [-0.44,0.48], I&lt;sup&gt;2&lt;/sup&gt; = 0%,P = 0.93) or speech (SMD = 0.04, 95% CI [-0.39, 0.47], I&lt;sup&gt;2&lt;/sup&gt; = 0%, P = 0.86) in children with ASD. 

Conclusion(s): MT can improve social skills in children with ASD; however, there does not seem to be a consensus on the persistence of its effects. These findings can inform clinical practice. Promoting the use of MT in children with ASD and improving its symptoms are the ultimate goals. Copyright &copy; 2022 Ke, Song, Yang, Li and Liu.
AN  - 2019678468
AU  - Ke,
AU  - X.
AU  - Song,
AU  - W.
AU  - Yang,
AU  - M.
AU  - Li,
AU  - J.
AU  - Liu,
AU  - W.
DB  - Alerts 6_2022.enl
DO  - /10.3389/fpsyt.2022.905113
L1  - internal-pdf://1046530550/Ke_2022.pdf
PY  - 2022
T2  - Frontiers in Psychiatry
TI  - Effectiveness of music therapy in children with autism spectrum disorder: A systematic review and meta-analysis
UR  - http://www.frontiersin.org/Psychiatry
VL  - 13 (no pagination)
ER  -
TY  - JOUR
AB  - **Background:**

Infants of parents with perinatal anxiety are at elevated likelihood of experiencing disruption in the parent-infant relationship, as well as difficulties with socio-emotional functioning in later development. Interventions delivered in the perinatal period have the potential to protect the early dyadic relationship and support infants&#039; ongoing development and socio-emotional outcomes. This review primarily aimed to examine the efficacy of perinatal interventions on parent anxiety, infant socio-emotional development/temperament, and parent-infant relationship outcomes. Secondarily, the review sought to understand how interventions focused principally on one member of the dyad affected the outcomes of the other, and which intervention components were common to successful interventions. 

**Method:**

Five electronic databases as well as manual search procedures were used to identify randomised controlled trials according to a PICO eligibility criteria framework. Risk of bias assessments were undertaken, and a narrative synthesis was conducted. The review was pre-registered on PROSPERO (CRD42021254799). 

**Results:**

Twelve studies were analysed in total, including five interventions focused on the adult, and seven interventions focused on the infant, or the infant&#039;s relationship with their parent. Interventions incorporating cognitive behavioural strategies for affective disorders showed reductions in parent anxiety (N = 3), and interventions focusing on altering distorted maternal internal representations showed positive change in parent-child dyadic interactions, and infant outcomes (N = 2). Evidence that interventions focused on one partner of the dyad led to improved outcomes for the other partner was limited. However, evidence was of mixed methodological quality.

**Conclusions:**

It is important to integrate both parents and infants into treatment programmes for perinatal anxiety. Implications for clinical practice and future intervention trials are discussed.
AN  - 37431423
AU  - Smith,
AU  - C.
AU  - G.
AU  - Jones,
AU  - E.
AU  - J.
AU  - H.
AU  - Wass,
AU  - S.
AU  - V.
AU  - Jacobs,
AU  - D.
AU  - Fitzpatrick,
AU  - C.
AU  - Charman,
AU  - T.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/jcv2.12116
L1  - internal-pdf://3282710242/Smith-2022-The effect of perinatal interventio.pdf
PY  - 2022
SP  - e12116
T2  - Jcpp Advances
TI  - The effect of perinatal interventions on parent anxiety, infant socio-emotional development and parent-infant relationship outcomes: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=37431423
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10242933/pdf/JCV2-2-e12116.pdf
VL  - 2
ER  -
TY  - JOUR
AB  - **Objective:**
Exercise has beneficial effects on mood and anxiety symptoms. However, the impact of aquatic exercise on mood and anxiety symptoms has not been clearly confirmed. Therefore, this study aimed to synthesize and systematically analyze evidence available on boosting mental health through aquatic exercise. 

**Method:**
A systematic review and meta-analysis were conducted under the PRISMA 2020 guidelines. PubMed, BIOSIS Previews, PsycINFO, Medline, SPORTDiscus, Education Source, and Web of Science Core Collection (WoSCC) were searched in May 2022. The research included the influence of aquatic exercises on mood and anxiety symptoms. After assessing trial quality and completing data extraction, a meta-analysis was carried out through R software. The results were presented as a standardized mean difference (SMD) and the corresponding 95% confidence interval. 

**Results:**
A total of 18 original trials were included. People who received aquatic exercise intervention had a statistically significant reduction in mental disorder symptoms compared with before. The results were aquatic exercise [SMD = -0.77, 95% CI (-1.08, -0.47), I-2 = 77%, P &lt; 0.01], swimming [SMD = -0.51, 95% CI (-1.14, 0.12), I-2 = 78%, P &lt; 0.01], aquatic aerobics [SMD = -0.92, 95% CI (-1.32, -0.53), I-2 = 78%, P &lt; 0.01], moderate intensity [SMD = -0.75, 95% CI (-1.07, -0.43), I-2 = 67%, P &lt; 0.01], and low intensity [SMD = -1.07, 95% CI (-1.08, -0.47), I-2 = 85%, P &lt; 0.01]. 

**Conclusion:**
Aquatic exercise could statistically significantly improve mental health. Light aquatic aerobics probably has a better effect on mood and anxiety symptoms. However, given the number and quality of included research, verifying the aforementioned conclusions requires a larger sample of high-quality studies.
AN  - WOS:000911094000001
AU  - Tang,
AU  - Z.
AU  - Y.
AU  - Wang,
AU  - Y.
AU  - Liu,
AU  - J.
AU  - M.
AU  - Liu,
AU  - Y.
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.3389/fpsyt.2022.1051551
L1  - internal-pdf://0201920036/pdf.cleaned (1).pdf
PY  - 2022
SP  - 18
T2  - Frontiers in Psychiatry
TI  - Effects of aquatic exercise on mood and anxiety symptoms: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000911094000001
VL  - 13
ER  -
TY  - JOUR
AB  - Transcranial magnetic stimulation (TMS) is a non-invasive treatment for adolescent major depressive disorder (MDD). Existing evidence on the efficacy of TMS in adolescent MDD awaits quantitative synthesis. 

A systematic literature search was conducted, and data from eligible studies were synthesized using random-effects models. Treatment-covariate interactions were examined in exploratory analyses of individual-patient data (IPD). Systematic search of the literature yielded 1264 hits, of which 10 individual studies (2 randomized trials) were included for quantitative synthesis of mainly uncontrolled studies. Individual patient data (IPD) were available from five trials (all uncontrolled studies). Quantitative synthesis of aggregated data revealed a statistically significant negative overall standardized mean change (pooled SMCC = 2.04, 95% CI [1.46; 2.61], SE = 0.29, p &lt; .001), as well as a significant overall treatment response rate (Transformed Proportion = 41.30%, 95% CI [31.03; 51.57], SE = 0.05; p &lt; 0.001), considering data from baseline to post-treatment. Exploratory IPD analyses suggests TMS might be more effective in younger individuals and individuals with more severe depression, and efficacy might be enhanced with certain treatment modality settings, including higher number of TMS sessions, longer treatment durations, and unilateral and not bilateral stimulation. 

Existing studies exhibit methodological shortcomings, including small-study effects and lack of control group, blinding, and randomization-compromising the credibility of the present results. To date, two randomized controlled trials on TMS in adolescent depression have been published, and the only large-scale randomized trial suggests TMS is not more effective than sham stimulation. Future large-scale, randomized, and sham-controlled trials are warranted. Future trials should ensure appropriate selection of patients for TMS treatment and guide precision medicine approaches for stimulation protocols.
AN  - 35751003
AU  - Sigrist,
AU  - C.
AU  - Vockel,
AU  - J.
AU  - MacMaster,
AU  - F.
AU  - P.
AU  - Farzan,
AU  - F.
AU  - Croarkin,
AU  - P.
AU  - E.
AU  - Galletly,
AU  - C.
AU  - Kaess,
AU  - M.
AU  - Bender,
AU  - S.
AU  - Koenig,
AU  - J.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s00787-022-02021-7
L1  - internal-pdf://2528104567/Sigrist-2022-Transcranial magnetic stimulation.pdf
PY  - 2022
SP  - 24
T2  - European Child &amp; Adolescent Psychiatry
TI  - Transcranial magnetic stimulation in the treatment of adolescent depression: a systematic review and meta-analysis of aggregated and individual-patient data from uncontrolled studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35751003
UR  - https://link.springer.com/content/pdf/10.1007/s00787-022-02021-7.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - **Background:** 
Studies have shown that pharmacological and psychological treatments are effective for children and adolescents with obsessive-compulsive disorder (OCD). However, few network meta-analyses have examined whether pharmacological or psychological treatments on their own, or combined, are most effective. 

**Method(s):** 
We conducted a database search and selected randomized controlled trials of pharmacological or psychological treatments, alone or in combination, for children and adolescents with OCD. The primary outcome was change in symptom severity as a result of treatment, as assessed using the Yale-Brown Obsessive Compulsive Scale (YBOCS) or Children&#039;s Yale-Brown Obsessive Compulsive Scale (CY-BOCS). 

**Result(s):** 
We included 18 studies with 1353 participants and 12 kinds of treatments. In terms of efficacy, all pharmacological and psychotherapy treatments were more effective than placebo. Among the 12 treatments, the efficacy of pharmacological treatment combined with cognitive behavioral therapy (CBT) was more effective than pharmacological treatment alone. When pharmacological treatment was used alone, escitalopram was significantly more effective than clomipramine (CY-BOCS average change 3.42; 95% CI 2.11, 4.65), fluvoxamine (CY-BOCS average change 3.59; 95% CI 1.09, 6.20), paroxetine (CY-BOCS average change 2.80; 95% CI 0.01, 5.64) and sertraline (CY-BOCS average change 3.49; 95% CI 1.53, 5.64). 

**Conclusion(s):** 
The available evidence suggests that the combination of pharmacological and psychological treatment is likely to be most effective for children and adolescents with OCD. Copyright &copy; 2022 Elsevier Ltd
AN  - 2016734926
AU  - Tao,
AU  - Y.
AU  - Li,
AU  - H.
AU  - Li,
AU  - L.
AU  - Xu,
AU  - H.
AU  - Zhang,
AU  - H.
AU  - Zou,
AU  - S.
AU  - Deng,
AU  - F.
AU  - Huang,
AU  - L.
AU  - Wang,
AU  - Y.
AU  - Wang,
AU  - X.
AU  - Tang,
AU  - X.
AU  - Fu,
AU  - X.
AU  - Yin,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jpsychires.2022.01.057
L1  - internal-pdf://1501367334/Comparing the efficacy of pharmacological-2022.pdf
PY  - 2022
SP  - 95-102
T2  - Journal of Psychiatric Research
TI  - Comparing the efficacy of pharmacological and psychological treatment, alone and in combination, in children and adolescents with obsessive-compulsive disorder: A network meta-analysis
UR  - https://www.elsevier.com/locate/jpsychires
UR  - https://www.sciencedirect.com/science/article/pii/S0022395622000668?via%3Dihub
VL  - 148
ER  -
TY  - JOUR
AB  - Presents a study which aims to conduct a systematic review and meta analysis to examine the effects of physical activity interventions on posttraumatic growth after a traumatic event. The authors also examined the potential moderators of the intervention&#039;s effectiveness, including intervention characteristics, methodological characteristics, and participant characteristics. The planning and implementation of this systematic review and meta-analysis was guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The authors conducted a comprehensive search of six databases (CENTRAL, Embase, PubMed, Web of Science, PsycINFO, and SPORTDiscus) to identify articles on physical activity interventions and posttraumatic growth. They used both Medical Subject Headings and key terms to maximize the retrieval of relevant articles. This study synthesized the current evidence for the effects of physical activity interventions on posttraumatic growth. Physical activity interventions have a small-to-medium postive effect on posttraumatic growth. As an alternative or supplement to psychosocial interventions, physical activity may serve as a beneficial approach for facilitating posttraumatic growth. Further research should prioritize randomized controlled trial designs and investigate various types of physical activity in both medical and non-medical contexts. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-15280-001
AU  - Zhang,
AU  - N.
AU  - Xiang,
AU  - X.
AU  - Zhou,
AU  - S.
AU  - Liu,
AU  - H.
AU  - He,
AU  - Y.
AU  - Chen,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jpsychores.2021.110675
L1  - internal-pdf://2832732112/Physical activity intervention and posttr-2022.pdf
PY  - 2022
T2  - Journal of Psychosomatic Research Vol 152 2022, ArtID 110675
TI  - Physical activity intervention and posttraumatic growth: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-15280-001
UR  - https://www.sciencedirect.com/science/article/pii/S0022399921003202?via%3Dihub
VL  - 152
ER  -
TY  - JOUR
AB  - Day programs have received significant consideration within psychological literature as part of a continuum of mental health services. With increasing attention on the prevalence of eating disorders in children and adolescents, and the need for early intervention to minimize the costs and burden of the disorder, eating disorder day programs (also referred as partial hospitalization) have begun to emerge around the world. Despite their widespread use, no reviews to date have examined the efficacy of day programs for the treatment of eating disorders in children and adolescents. The current narrative literature review aims to describe and evaluate the efficacy of day programs for children and adolescents. The literature review was conducted according to the PRISMA guidelines and aimed to explore the outcomes and common program elements of day programs to guide clinical practice and service development. The review found variations amongst the day programs related to program elements, measures utilized and outcomes. Overall, the results suggest that day programs for children and adolescents are effective at restoring body weight, reducing eating disorder symptoms and addressing comorbid mental health concerns.
AN  - 36351879
AU  - Krishnamoorthy,
AU  - G.
AU  - Shin,
AU  - S.
AU  - M.
AU  - Rees,
AU  - B.
DB  - Alerts 6_2022.enl
DO  - /10.1002/erv.2953
L1  - internal-pdf://1522846401/Euro Eating Disorders Rev - 2022 - Krishnamoor.pdf
PY  - 2022
SP  - 09
T2  - European Eating Disorders Review
TI  - Day Programs for children and adolescents with eating disorders: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36351879
VL  - 09
ER  -
TY  - JOUR
AB  - **Background:**
The worldwide prevalence of paternal perinatal anxiety (PPA) ranges between 3.4% and 25.0% antenatally, and 2.4% and 51.0% postnatally. Experiencing PPA can adversely impact the individual, partners, and infants. Research concerning PPA is lagging and fragmented compared to research for new mothers. 

**Objectives:** 
To establish the effectiveness of prevention or treatment interventions for PPA in adults identifying as male. 

**Data sources:** We completed searches of Medline, EMBASE, PsycINFO and Web of Science from inception to 2 December 2021, as well as hand searches of references from relevant papers. 

**Search selection and data extraction:**
Randomised controlled trials delivering prevention or treatment interventions and reporting anxiety outcomes for new/expectant fathers in the perinatal mental health period were included. Our review follows the PRISMA reporting guidelines. One reviewer independently screened 5170 titles/abstracts; second reviewers screened 50%. Two reviewers independently screened full text, extracted data, and conducted risk of bias assessments.

**Synthesis:** 
Cochrane&#039;s collaboration tool 2 was used to assess quality. Primarily results are synthesised narratively, a post-hoc sub-group analysis was completed on four studies using the same outcome measure. 

**Main results:** 
Twelve of the 5170 studies fulfilled the inclusion criteria. Studies used psychoeducational or practical skills interventions. Interventions mostly involved couple-dyads and three studies assessed PPA as a primary outcome. Included interventions were prevention-based; no treatment interventions were found. Father-only interventions consistently reported a significant reduction of PPA.
AN  - 36431094
AU  - Fisher,
AU  - M.
AU  - L.
AU  - Sutcliffe,
AU  - P.
AU  - Southern,
AU  - C.
AU  - Grove,
AU  - A.
AU  - L.
AU  - Tan,
AU  - B.
AU  - K.
DB  - Alerts 6_2022.enl
DO  - /10.3390/jcm11226617
L1  - internal-pdf://2401092728/Fisher-2022-The Effectiveness of Interventions.pdf
PY  - 2022
SP  - 08
T2  - Journal of Clinical Medicine
TI  - The Effectiveness of Interventions for the Prevention or Treatment of Paternal Perinatal Anxiety: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36431094
UR  - https://mdpi-res.com/d_attachment/jcm/jcm-11-06617/article_deploy/jcm-11-06617-v2.pdf?version=1668588072
VL  - 11
ER  -
TY  - JOUR
AB  - **Background**
Social interaction and social communication are among the central areas of difficulty for autistic people. Music therapy uses music experiences and the relationships that develop through them to enable communication and expression, thus attempting to address some of the core problems of autistic people. Music therapy has been applied in autism since the early 1950s, but its availability to autistic individuals varies across countries and settings. The application of music therapy requires specialised academic and clinical training which enables therapists to tailor the intervention to the specific needs of the individual. The present version of this review on music therapy for autistic people is an update of the previous Cochrane review update published in 2014 (following the original Cochrane review published in 2006).

**Objectives**
To review the effects of music therapy, or music therapy added to standard care, for autistic people.

**Search methods**
In August 2021, we searched CENTRAL, MEDLINE, Embase, eleven other databases and two trials registers. We also ran citation searches, checked reference lists, and contacted study authors to identify additional studies.

**Selection criteria**
All randomised controlled trials (RCTs), quasi‐randomised trials and controlled clinical trials comparing music therapy (or music therapy alongside standard care) to &#039;placebo&#039; therapy, no treatment, or standard care for people with a diagnosis of autism spectrum disorder were considered for inclusion.

**Data collection and analysis**
We used standard Cochrane methodological procedures. Four authors independently selected studies and extracted data from all included studies. We synthesised the results of included studies in meta‐analyses. Four authors independently assessed risk of bias (RoB) of each included study using the original RoB tool as well as the certainty of evidence using GRADE. 

**Main results**
We included 16 new studies in this update which brought the total number of included studies to 26 (1165 participants). These studies examined the short‐ and medium‐term effect of music therapy (intervention duration: three days to eight months) for autistic people in individual or group settings. More than half of the studies were conducted in North America or Asia. Twenty‐one studies included children aged from two to 12 years. Five studies included children and adolescents, and/or young adults. Severity levels, language skills, and cognition were widely variable across studies.

Measured immediately post‐intervention, music therapy compared with &#039;placebo&#039; therapy or standard care was more likely to positively effect global improvement (risk ratio (RR) 1.22, 95% confidence interval (CI) 1.06 to 1.40; 8 studies, 583 participants; moderate‐certainty evidence; number needed to treat for an additional beneficial outcome (NNTB) = 11 for low‐risk population, 95% CI 6 to 39; NNTB = 6 for high‐risk population, 95% CI 3 to 21) and to slightly increase quality of life (SMD 0.28, 95% CI 0.06 to 0.49; 3 RCTs, 340 participants; moderate‐certainty evidence, small to medium effect size). In addition, music therapy probably results in a large reduction in total autism symptom severity (SMD &minus;0.83, 95% CI &minus;1.41 to &minus;0.24; 9 studies, 575 participants; moderate‐certainty evidence). No clear evidence of a difference between music therapy and comparison groups at immediately post‐intervention was found for social interaction (SMD 0.26, 95% CI &minus;0.05 to 0.57, 12 studies, 603 participants; low‐certainty evidence); non‐verbal communication (SMD 0.26, 95% CI &minus;0.03 to 0.55; 7 RCTs, 192 participants; low‐certainty evidence); and verbal communication (SMD 0.30, 95% CI &minus;0.18 to 0.78; 8 studies, 276 participants; very low‐certainty evidence). Two studies investigated adverse events with one (36 participants) reporting no adverse events; the other study found no differences between music therapy and standard care immediately post‐intervention (RR 1.52, 95% CI 0.39 to 5.94; 1 study, 290 participants; moderate‐certainty evidence). 

**Authors&#039; conclusions**
The findings of this updated review provide evidence that music therapy is probably associated with an increased chance of global improvement for autistic people, likely helps them to improve total autism severity and quality of life, and probably does not increase adverse events immediately after the intervention. The certainty of the evidence was rated as &#039;moderate&#039; for these four outcomes, meaning that we are moderately confident in the effect estimate. No clear evidence of a difference was found for social interaction, non‐verbal communication, and verbal communication measured immediately post‐intervention. For these outcomes, the certainty of the evidence was rated as &#039;low&#039; or &#039;very low&#039;, meaning that the true effect may be substantially different from these results. Compared with earlier versions of this review, the new studies included in this update helped to increase the certainty and applicability of this review&#039;s findings through larger sample sizes, extended age groups, longer periods of intervention and inclusion of follow‐up assessments, and by predominantly using validated scales measuring generalised behaviour (i.e. behaviour outside of the therapy context). This new evidence is important for autistic individuals and their families as well as for policymakers, service providers and clinicians, to help in decisions around the types and amount of intervention that should be provided and in the planning of resources. The applicability of the findings is still limited to the age groups included in the studies, and no direct conclusions can be drawn about music therapy in autistic individuals above the young adult age. More research using rigorous designs, relevant outcome measures, and longer‐term follow‐up periods is needed to corroborate these findings and to examine whether the effects of music therapy are enduring.
AU  - Geretsegger,
AU  - M.
AU  - Fusar-Poli,
AU  - L.
AU  - Elefant,
AU  - C.
AU  - M&ouml;ssler,
AU  - K.
AU  - A.
AU  - Vitale,
AU  - G.
AU  - Gold,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD004381.pub4
L1  - internal-pdf://2981960288/Geretsegger_et_al-2022-Cochrane_Database_of_Sy.pdf
PY  - 2022
T2  - Cochrane Database of Systematic Reviews
TI  - Music therapy for autistic people
ER  -
TY  - JOUR
AB  - Children and youth treated with antipsychotic drugs (APs) are particularly vulnerable to adverse drug reactions (ADRs) and prone to poor treatment response. In particular, interindividual variations in drug exposure can result from differential metabolism of APs by cytochromes, subject to genetic polymorphism. CYP1A2 is pivotal in the metabolism of the APs olanzapine, clozapine, and loxapine, whose safety profile warrants caution. 

We aimed to shed some light on the pharmacogenetic profiles possibly associated with these drugs&#039; ADRs and loss of efficacy in children and youth. 

We conducted a systematic review relying on four databases, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 recommendations and checklist, with a quality assessment. 

Our research yielded 32 publications. The most frequent ADRs were weight gain and metabolic syndrome (18; 56.3%), followed by lack of therapeutic effect (8; 25%) and neurological ADRs (7; 21.8%). The overall mean quality score was 11.3/24 (+/- 2.7). In 11 studies (34.3%), genotyping focused on the study of cytochromes. 

Findings regarding possible associations were sometimes conflicting. Nonetheless, cases of major clinical improvement were fostered by genotyping. Yet, CYP1A2 remains poorly investigated. Further studies are required to improve the assessment of the risk-benefit balance of prescription for children and youth treated with olanzapine, clozapine, and/or loxapine.
AN  - WOS:000816187500001
AU  - Merino,
AU  - D.
AU  - Fernandez,
AU  - A.
AU  - Gerard,
AU  - A.
AU  - O.
AU  - Ben
AU  - Othman,
AU  - N.
AU  - Rocher,
AU  - F.
AU  - Askenazy,
AU  - F.
AU  - Verstuyft,
AU  - C.
AU  - Drici,
AU  - M.
AU  - D.
AU  - Thummler,
AU  - S.
DB  - Alerts 6_2022.enl
DO  - 10.3390/ph15060749
L1  - internal-pdf://0385600342/Merino-2022-Adverse Drug Reactions of Olanzapi.pdf
PY  - 2022
SP  - 27
T2  - Pharmaceuticals
TI  - Adverse Drug Reactions of Olanzapine, Clozapine and Loxapine in Children and Youth: A Systematic Pharmacogenetic Review
UR  - &lt;Go to ISI&gt;://WOS:000816187500001
UR  - https://mdpi-res.com/d_attachment/pharmaceuticals/pharmaceuticals-15-00749/article_deploy/pharmaceuticals-15-00749-v2.pdf?version=1655364031
VL  - 15
ER  -
TY  - JOUR
AB  - Research on the growth mindset interventions (GMIs) on nonacademic outcomes is burgeoning. The present systematic review aims to evaluate the effects of GMIs on social-emotional outcomes among school-aged children and adolescents. Using the PRIMSA guidelines, our search across three electronic databases (PsycINFO, ERIC, and PubMed) yielded an initial identification of 1057 records. Inclusion criteria include publication format, language, participant age range, and intervention purpose, focus and components. Risk of bias was analyzed at the study level using a list of research quality indicators and across studies by comparing nonpeer reviewed versus peer reviewed publications. Our final sample yielded 13 papers including 14 studies. The findings from these studies were extracted to examine research quality, sample characteristics, intervention content, and intervention effects of the GMIs. Results showed despite that study quality, samples, and intervention designs varied, core components of the interventions were highly similar. Intervention effect results suggest that mindsets can be changed toward a growth orientation through brief GMIs, and effectiveness of GMIs on social-emotional outcomes is promising, especially in reducing depressive symptoms and aggressive reactions to perceived social exclusion. Research gaps and future directions, and implications for school psychologists and other mental health professionals are discussed.Impact StatementThis is the first study to review growth mindset interventions that target social-emotional outcomes among school-aged children and adolescents. Reviews such as this are important for researchers, school psychologists and other mental health professionals, alike. For mindset researchers, it helps in conducting future empirical studies by considering empirical and methodological implications from previous intervention studies. For practitioners, it may help to design mindset interventions in more cost-effective ways that enable them to be integrated into school-based mental health prevention or intervention programs. Generally, such interventions are effective in changing youth mindset toward a growth orientation. Evidence suggests that such interventions help ameliorate depression from getting worse and reducing aggression when adolescents experience elevated social stress. Overall, growth mindset interventions show promise in improving social-emotional outcomes and cost-efficiency, especially in school settings.
AN  - WOS:000924747000001
AU  - Jiang,
AU  - X.
AU  - Mueller,
AU  - C.
AU  - E.
AU  - Paley,
AU  - N.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1080/2372966x.2022.2151321
L1  - internal-pdf://1920598808/A Systematic Review of Growth Mindset Interven.pdf
PY  - 2022
SP  - 22
T2  - School Psychology Review
TI  - A Systematic Review of Growth Mindset Interventions Targeting Youth Social-Emotional Outcomes
UR  - &lt;Go to ISI&gt;://WOS:000924747000001
ER  -
TY  - JOUR
AB  - BACKGROUND: 
The growing prevalence of mental health disorders in children and adolescents coupled with poor medication adherence in the paediatric population is a major problem within healthcare systems affecting patient outcomes. Digital health interventions (DHIs) are primed to optimise medication adherence given the expansion of digital health markets and the increased usage of digital technologies by children and adolescents. 

OBJECTIVE: 
This rapid systematic review evaluates the impact of DHIs on optimising medication adherence amongst children and adolescents with mental health disorders compared to treatment as usual (TAU). 

METHODS: 
A rapid systematic search in electronic databases CINAHL Plus, Cochrane Library, MEDLINE, PubMed, and Scopus was conducted. The scope of the rapid systematic search included randomised controlled trials and quasi-experimental studies (non-randomised controlled trials) evaluating DHIs optimising medication adherence in children and adolescents with attention deficit hyperactivity disorder (ADHD), depression and/or anxiety. Meta-analyses were conducted based on estimating pooled odds ratio (OR) and mean difference (MD) with 95% confidence interval using a random-effects model. Thematic analysis identified key avenues DHIs offer to optimise medication adherence. 

RESULTS: 
Four studies were found, with 502 participants included in the meta-analysis. An improvement in medication adherence was observed following DHIs for studies measuring dichotomous and continuous outcomes. However, the effect was not significant for the former. DHIs were shown to help bridge the gaps between patients and healthcare professionals, allowing for more frequent monitoring, communication, and assessments. 

CONCLUSIONS: 
Medication adherence amongst children and adolescents with acute or chronic ADHD, anxiety or depression may be positively impacted by DHIs, but better-powered studies with a lower risk of bias are necessary. The evidence currently remains inconclusive on DHIs improving medication adherence in children and adolescents.
AN  - 35985977
AU  - Vitija,
AU  - A.
AU  - Amirthalingam,
AU  - A.
AU  - Soltani,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.sapharm.2022.07.042
L1  - internal-pdf://0626560587/1-s2.0-S1551741122002315-main.cleaned.pdf
PY  - 2022
SP  - 02
T2  - Research In Social &amp; Administrative Pharmacy
TI  - The impact of digital interventions on medication adherence in paediatric populations with attention deficit hyperactivity disorder, depression, and/or anxiety: A rapid systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35985977
UR  - https://www.sciencedirect.com/science/article/pii/S1551741122002315?via%3Dihub
VL  - 02
ER  -
TY  - JOUR
AB  - OBJECTIVE: Depression and anxiety cause a high burden of disease and have high relapse rates (39%-72%). This meta-analysis systematically examined effectiveness of relapse prevention strategies on risk of and time to relapse in youth who remitted. 

METHOD: PubMed, PsycInfo, Embase, Cochrane, and ERIC databases were searched up to June 15, 2021. Eligible studies compared relapse prevention strategies to control conditions among youth (mean age 13-25 years) who were previously depressed or anxious or with &gt;=30% improvement in symptoms. Two reviewers independently assessed titles, abstracts, and full texts; extracted study data; and assessed risk of bias and overall strength of evidence. Random-effects models were used to pool results, and mixed-effects models were used for subgroup analyses. Main outcome was relapse rate at last follow-up (PROSPERO ID: CRD42020149326). 

RESULTS: Of 10 randomized controlled trials (RCTs) that examined depression, 9 were eligible for analysis: 4 included psychological interventions (n = 370), 3 included antidepressants (n = 80), and 2 included combinations (n = 132). No RCTs for anxiety were identified. Over 6 to 75 months, relapse was half as likely following psychological treatment compared with care as usual conditions (k = 6; odds ratio 0.56, 95% CI 0.31 to 1.00). Sensitivity analyses including only studies with &gt;=50 participants (k = 3), showed similar results. Over 6 to 12 months, relapse was less likely in youth receiving antidepressants compared with youth receiving pill placebo (k = 3; OR 0.29, 95% CI 0.10 to 0.82). Quality of studies was suboptimal. 

CONCLUSION: Relapse prevention strategies for youth depression reduce risk of relapse, although adequately powered, high-quality RCTs are needed. This finding, together with the lack of RCTs on anxiety, underscores the need to examine relapse prevention in youth facing these common mental health conditions.
AN  - 35513189
AU  - Robberegt,
AU  - S.
AU  - J.
AU  - Brouwer,
AU  - M.
AU  - E.
AU  - Kooiman,
AU  - Beam
AU  - Stikkelbroek,
AU  - Y.
AU  - A.
AU  - J.
AU  - Nauta,
AU  - M.
AU  - H.
AU  - Bockting,
AU  - C.
AU  - L.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2022.04.014
L1  - internal-pdf://1560227283/Meta-Analysis_ Relapse Prevention Strateg-2022.pdf
PY  - 2022
SP  - 02
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Meta-Analysis: Relapse Prevention Strategies for Depression and Anxiety in Remitted Adolescents and Young Adults
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35513189
UR  - https://www.sciencedirect.com/science/article/pii/S0890856722002441?via%3Dihub
VL  - 02
ER  -
TY  - JOUR
AB  - BAKGRUNN:
Skilsmissegrupper er et helsefremmende og forebyggende gruppebasert tiltak for barn og ungesom tilbys gjennom skolen, primært via helsesykepleier. Målet med tiltaket er å gi barn somopplever samlivsbrudd i familien en arena for å møte andre barn som har lignende erfaringer, åkunne snakke med andre enn foreldrene om hvordan det oppleves, og å bli bedre i stand til åhåndtere (den nye) hverdagen. Tiltaket ble utviklet tidlig på 2000-tallet av to helsesykepleiere, ogdrives i dag gjennom organisasjonen Voksne for Barn.

METODE:
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase,Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt iinternasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fratiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiskeeffektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

RESULTATER:
Resultatene i denne kunnskapsoppsummeringen består av en vurdering av tiltakets beskrivelse,foreliggende studier, og implementeringskvalitet. Skilsmissegrupper er godt beskrevet og bygger pået kjent teorigrunnlag. Videre bygger denne kunnskapsoppsummeringen på tre kvalitative studiersom har undersøkt både ungdommenes og utøvernes opplevelse med gruppene, samt enevalueringsrapport, men det foreligger ingen nordiske effektstudier av tiltaket hvilket gjør detvanskelig å si noe om effekten av tiltaket.

KONKLUSJON:
Skilsmissegrupper klassifiseres på evidensnivå 2 &ndash; Teoretisk begrunnet tiltak
AU  - Rasmussen,
AU  - L-M.
AU  - P.,
AU  - Christiansen,
AU  - Ø.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /post_tiltak_arkiv/skilsmissegrupper-2-utg/
L1  - internal-pdf://4050367885/Skilsmissegrupper-2.utg-2022 (1).pdf
PY  - 2022
T2  - Ungsinn
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Skilsmissegrupper (2. utg.)
ER  -
TY  - JOUR
AB  - The serotonergic system is implicated in ADHD, but the impact of serotonin&#039;s precursor molecule, tryptophan, on ADHD symptomology remains unclear. Systematic searches of randomised controlled trials with an experimental tryptophan intervention in children and adults with ADHD identified 14 studies measuring core and related symptoms of the condition. Risk of bias was assessed using the Cochrane Risk of Bias tool. The 14 studies all used acute tryptophan depletion procedures, and most did not investigate core ADHD symptoms (inattention, impulsivity, hyperactivity) as primary outcome measures. Only two studies examined attention and revealed mixed effects of tryptophan. Similar effects were found for impulsivity in a small number of studies. No studies investigated hyperactivity. Most studies focused on reactive aggression, but samples were heterogenous and small, rendering potential meta-analyses inconclusive or misleading. However, the narrative analysis indicates tryptophan interventions may impact reactive aggression. More research is needed on the effect of tryptophan modulation on core ADHD symptoms, especially in adults, using more diverse samples to determine potential as an intervention. From current data, tryptophan modulation appears to alter aggressive behaviour in ADHD; however, the available studies were insufficient for the planned meta-analysis.
AN  - 35286460
AU  - Dinu,
AU  - L.
AU  - M.
AU  - Phattharakulnij,
AU  - N.
AU  - Dommett,
AU  - E.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00702-022-02478-5
L1  - internal-pdf://2514939440/Tryptophan modulation in individuals with-2022.pdf
PY  - 2022
SP  - 14
T2  - Journal of Neural Transmission
TI  - Tryptophan modulation in individuals with attention deficit hyperactivity disorder: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35286460
UR  - https://link.springer.com/content/pdf/10.1007/s00702-022-02478-5.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Behavior therapy is identified as an evidence-based treatment for adolescents with ADHD. To date, there is no literature comparing and contrasting the content of existing behavior therapy packages. This review explores the heterogeneity of evidence-based behavior therapies for adolescents with ADHD by identifying the differences and commonalities amongst them. We conducted a systematic review of the literature and identified six treatment packages that met our inclusion criteria. Qualitative coding of practice elements employed a distillation approach based on review of treatment materials from each identified package. Practice elements were sorted into categories of common, shared, or unique elements. We identified 22 practice elements in total: 5 common elements, 11 shared, and 6 unique. Common elements represented skills training (organization and time management skills) and behavior management (skill application assignments, progress monitoring, use of rewards) elements. The list of shared elements primarily comprised varying engagement and skill generalization components designed to support the success of common elements. Unique elements were primarily skills-based: social skills training and peer-based recreation activities (Challenging Horizons Program), parent-teen communication training (Supporting Teens&#039; Autonomy Daily), and distractibility reduction training and cognitive restructuring (Cognitive-Behavioral Therapy), but also included behavior modification (Challenging Horizons Program). Evidence-based psychosocial treatments for adolescents with ADHD overlap substantially and include more common and shared than unique elements. In adolescence, ADHD psychosocial therapies represent hybrid training and behavior management interventions. Community-based adaptations of evidence-based treatments should retain common elements and consider modular implementation of shared and unique elements. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2023-16815-001
AU  - Rios-Davis,
AU  - A.
AU  - Sibley,
AU  - M.
AU  - H.
AU  - Delgado,
AU  - A.
AU  - Zulauf-McCurdy,
AU  - C.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s10826-022-02475-y
L1  - internal-pdf://3089291327/Rios-Davis-2022-Identifying common and unique.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Journal of Child and Family Studies
TI  - Identifying common and unique elements of evidence-based treatments for adolescent adhd
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc19&amp;AN=2023-16815-001
UR  - https://link.springer.com/content/pdf/10.1007/s10826-022-02475-y.pdf
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Although some meta-analyses have identified potential moderators associated with treatment outcomes for pediatric obsessive-compulsive disorder (OCD), there is as yet no consensus regarding the influence of anxiety and depression symptoms on the recovery from pediatric OCD. A meta-analysis was conducted to investigate the effects of depression and anxiety symptoms and their comorbidities on the efficacy of CBT in pediatric OCD, as well as other potential moderators that may be associated with outcomes. 

**METHOD**
An exhaustive literature search from 1983 to March 2021 located 22 published articles that applied cognitive-behavioral therapy (CBT) to pediatric OCD, producing a total of 26 treatment groups. Some of the moderator variables analyzed included age, gender, comorbidity baseline in anxiety, depression and obsession, and methodological quality. 

**RESULTS**
Results showed that the psychological treatment of OCD achieves clinically significant effectiveness, both for measures of obsessions and compulsions ( d + = 2.030), and for anxiety ( d + = 0.613) and depression ( d + = 0.451). An explanatory model for the CY-BOCS effect sizes showed that three moderator variables were statistically related: the mean of the CY-BOCS (Children&#039;s Yale Brown Obsessive Compulsive Scale) in pretest, the effect size for anxiety, and the mean age of the sample. 

**CONCLUSIONS** 
CBT reduced obsessive-compulsive symptoms and, to a lesser extent, anxiety and depression symptoms. Since anxiety symptoms are reduced with the same therapy, resources would be saved compared to other treatments.
AN  - 35860997
AU  - Rosa-Alcazar,
AU  - A.
AU  - Sanchez-Meca,
AU  - J.
AU  - Rubio-Aparicio,
AU  - M.
AU  - Bernal-Ruiz,
AU  - C.
AU  - Rosa-Alcazar,
AU  - A.
AU  - I.
DB  - Alerts 6_2022.enl
DO  - /10.7334/psicothema2021.478
L1  - internal-pdf://3860123235/Rosa-Alcazar-2022-Cognitive-Behavioral Therapy.pdf
PY  - 2022
SP  - 353-364
T2  - Psicothema
TI  - Cognitive-Behavioral Therapy and Anxiety and Depression Level in Pediatric Obsessive-Compulsive Disorder: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35860997
VL  - 34
ER  -
TY  - JOUR
AB  - **Purpose** 
Depressive disorders in children and adolescents have an enormous impact on their general quality of life. There is a clear need to effectively treat depression in this age group. Effects of psychotherapy can be enhanced by involving caregivers. In our systematic review and meta-analysis, we examine for the first time the effects of caregiver involvement in depression-specific interventions for children and adolescents. 

**Methods** 
We included randomized controlled trials examining the effects of interventions for children and adolescents with depression involving their caregivers or families compared to interventions without including caregivers. Primary outcome was the severity of childhood and adolescent depression. 

**Results** 
Overall, 19 randomized controlled trials could be included (N = 1553) that were highly heterogeneous regarding outcome measures or the extent of caregiver integration. We were able to include k = 17 studies in our meta-analysis and find a small but significant effect for family-involved interventions against active control conditions without family-involvement at post intervention (alpha = 0.05, d = 0.34; [0.07; 0.60]; p = .01). 

**Conclusions** 
We detected an overall significant but small effect of family/caregivers&#039; involvement compared to control groups without it. Structured, guideline-based research is urgently needed to identify for which children/adolescents with depression, under what circumstances, and in what form the family should be effectively involved in their psychotherapy. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-45388-001
AU  - Dippel,
AU  - N.
AU  - Szota,
AU  - K.
AU  - Cuijpers,
AU  - P.
AU  - Christiansen,
AU  - H.
AU  - Brakemeier,
AU  - E-L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/papt.12392
L1  - internal-pdf://0230623811/Family involvement in psychotherapy for d-2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Psychology and Psychotherapy: Theory, Research and Practice
TI  - Family involvement in psychotherapy for depression in children and adolescents: Systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-45388-001
ER  -
TY  - JOUR
AB  - **Background**
The steadily increasing prevalence of mental disorders in children and adolescents presents itself as a public health challenge, especially given the health, social and economic burden of mental disorders. School-based interventions aimed at improving mental health literacy and reducing mental health stigma have the potential to prevent mental disorders and promote mental well-being, thus reducing the burden of mental disorders. This review identified and synthesised evidence on the effectiveness of school-based interventions designed to improve mental health literacy and reduce mental health stigma. 

**Methods**
Electronic bibliographic databases including MEDLINE, Embase, PsycINFO, Education Resources Information Center (ERIC), Child Development and Adolescent Studies, British Education Index and Applied Social Sciences Index and Abstracts (ASSIA) were searched. Randomised controlled trials (RCTs) were included if they assessed the effectiveness or cost-effectiveness of school-based intervention aimed at improving mental health literacy and reducing mental health stigma for children and young people aged 4-18 years. Quality of studies was appraised using the EPHPP tool. A numerical summary and a narrative description of the findings in relation to the research questions were synthesised. This systematic review was registered with PROSPERO (CRD42020191265). 

**Results**
We identified 21 studies describing 20 unique school-based mental health interventions. Overall, there is moderate evidence suggesting that school-based mental health interventions can be effective in improving mental health literacy and reducing mental health stigma defined as attitudes and beliefs regarding mental disorders. However, there is less evidence for their long-term effectiveness, as most studies did not include follow-ups. 

**Conclusions**
Despite exclusively including studies with randomised designs, intervention and methodological heterogeneity poses uncertainties to any conclusions made. Future research should focus on resolving methodological issues concerning how outcomes are assessed and include process evaluations to better inform the design of an intervention in term of its delivery and implementation. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-22526-001
AU  - Ma,
AU  - K.
AU  - K.
AU  - Y.
AU  - Anderson,
AU  - J.
AU  - K.
AU  - Burn,
AU  - A.-M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/camh.12543
L1  - internal-pdf://1525522419/Review_ School-based interventions to imp-2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Child and Adolescent Mental Health
TI  - Review: School-based interventions to improve mental health literacy and reduce mental health stigma - a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-22526-001
UR  - https://acamh.onlinelibrary.wiley.com/doi/10.1111/camh.12543
ER  -
TY  - JOUR
AB  - **Background**
Robot-mediated interventions show promise in supporting the development of children on the autism spectrum. 

**Objectives**
In this systematic review and meta-analysis, we summarize key features of available evidence on robot-interventions for children and young people on the autism spectrum aged up to 18 years old, as well as consider their efficacy for specific domains of learning. Data sources PubMed, Scopus, EBSCOhost, Google Scholar, Cochrane Library, ACM Digital Library, and IEEE Xplore. Grey literature was also searched using PsycExtra, OpenGrey, British Library EThOS, and the British Library Catalogue. Databases were searched from inception until April (6th) 2021. 

**Synthesis methods**
Searches undertaken across seven databases yielded 2145 articles. Forty studies met our review inclusion criteria of which 17 were randomized control trials. The methodological quality of studies was conducted with the Quality Assessment Tool for Quantitative Studies. A narrative synthesis summarised the findings. A meta-analysis was conducted with 12 RCTs. 

**Results**
Most interventions used humanoid (67%) robotic platforms, were predominantly based in clinics (37%) followed home, schools and laboratory (17% respectively) environments and targeted at improving social and communication skills (77%). Focusing on the most common outcomes, a random effects meta-analysis of RCTs showed that robot-mediated interventions significantly improved social functioning (g = 0.35 [95%CI 0.09 to 0.61; k = 7). By contrast, robots did not improve emotional (g = 0.63 [95%CI -1.43 to 2.69]; k = 2) or motor outcomes (g = -0.10 [95%CI -1.08 to 0.89]; k = 3), but the numbers of trials were very small. Meta-regression revealed that age accounted for almost one-third of the variance in effect sizes, with greater benefits being found in younger children. 

**Conclusions**
Overall, our findings support the use of robot-mediated interventions for autistic children and youth, and we propose several recommendations for future research to aid learning and enhance implementation in everyday settings. Copyright &copy; 2022 Kouroupa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AN  - 2018943932
AU  - Kouroupa,
AU  - A.
AU  - Laws,
AU  - K.
AU  - R.
AU  - Irvine,
AU  - K.
AU  - Mengoni,
AU  - S.
AU  - E.
AU  - Baird,
AU  - A.
AU  - Sharma,
AU  - S.
DB  - Alerts 6_2022.enl
DO  - /10.1371/journal.pone.0269800
L1  - internal-pdf://1584319052/Kouroupa-2022-The use of social robots with ch.pdf
PY  - 2022
T2  - PLoS ONE [Electronic Resource]
TI  - The use of social robots with children and young people on the autism spectrum: A systematic review and meta-analysis
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0269800&amp;type=printable
VL  - 17(6 June) (no pagination)
ER  -
TY  - JOUR
AB  - Various forms of cognitive behavioral therapy for insomnia (CBT-i) have been developed to improve its scalability and accessibility for insomnia management in young people, but the efficacy of digitally-delivered cognitive behavioral therapy for insomnia (dCBT-i) remains uncertain. This study systematically reviewed and evaluated the effectiveness of dCBT-i among young individuals with insomnia. We conducted comprehensive searches using four electronic databases (PubMed, Cochrane Library, PsycINFO, and Embase; until October 2021) and examined eligible records. The search strategy comprised the following three main concepts: (1) participants were adolescents or active college students; (2) dCBT-I was employed; (3) standardized tools were used for outcome measurement. Four randomized controlled trials qualified for meta-analysis. A significant improvement in self-reported sleep quality with a medium-to-large effect size after treatment (Hedges&#039;s g = -0.58~-0.80) was noted. However, a limited effect was detected regarding objective sleep quality improvement (total sleep time and sleep efficiency measured using actigraphy). These preliminary findings from the meta-analysis suggest that dCBT-i is a moderately effective treatment in managing insomnia in younger age groups, and CBT-i delivered through the web or a mobile application is an acceptable approach for promoting sleep health in young people.
AN  - 35330480
AU  - Tsai,
AU  - H.
AU  - J.
AU  - Yang,
AU  - A.
AU  - C.
AU  - Zhu,
AU  - J.
AU  - D.
AU  - Hsu,
AU  - Y.
AU  - Y.
AU  - Hsu,
AU  - T.
AU  - F.
AU  - Tsai,
AU  - S.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/jpm12030481
L1  - internal-pdf://3021122698/Effectiveness of Digital Cognitive Behavi-2022.pdf
PY  - 2022
SP  - 16
T2  - Journal of Personalized Medicine
TI  - Effectiveness of Digital Cognitive Behavioral Therapy for Insomnia in Young People: Preliminary Findings from Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35330480
UR  - https://mdpi-res.com/d_attachment/jpm/jpm-12-00481/article_deploy/jpm-12-00481.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - BACKGROUND: Preoperative anxiety in pediatric patients can affect the course of surgery and cause adverse outcomes. Distraction is used as a measure to reduce preoperative anxiety in pediatric patients. 

OBJECTIVE: This study aimed to evaluate the effect of distraction on preoperative anxiety in pediatric patients. 

METHODS: We searched randomized controlled trials in databases (PubMed, Embase, Cochrane Library and ProQuest). Relevant studies were included by strict adherence to the inclusion and exclusion criteria, and intervention methods included a variety of distraction measures compared with routine care. The primary outcome was anxiety level after the intervention in holding area and (or) induction room measured by the modified Yale Preoperative anxiety Scale. Two researchers independently screened and extracted relevant data. A random-effects model was utilized to analysis the effect size as there was significant heterogeneity among the included studies. To further explore the reasons for potential heterogeneity and the effects of different distraction interventions, subgroup analysis was performed. 

RESULTS: Our search retrieved 793 records. 44 trials were included for qualitative analysis, of which 19 randomized controlled trials with 1341 patients were included for meta-analysis. Our study suggested a decreasing anxiety level of 5.34 versus 15.28 points respectively in holding area and induction room, where the distraction interventions group compared to the control group (MD: -5.34, 95% CI: -7.97 to -2.71 at holding aera; MD: -15.28, 95% CI: -21.48 to -9.09 at induction room). According to subgroup analysis, all subgroups showed significant effects of distraction on preoperative anxiety in pediatric patients. However, the heterogeneity between studies was high. 

CONCLUSION: Distraction as a preoperative anxiety management technique can benefit pediatric patients undergoing elective surgery, and healthcare personnel can apply preoperatively to alleviate preoperative anxiety in pediatric patients. 

REGISTRATION: not registered. TWEETABLE ABSTRACT: none.
AN  - 35367844
AU  - Wu,
AU  - J.
AU  - Yan,
AU  - J.
AU  - Zhang,
AU  - L.
AU  - Chen,
AU  - J.
AU  - Cheng,
AU  - Y.
AU  - Wang,
AU  - Y.
AU  - Zhu,
AU  - M.
AU  - Cheng,
AU  - L.
AU  - Zhang,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ijnurstu.2022.104232
L1  - internal-pdf://2819975325/The effectiveness of distraction as preop-2022.pdf
PY  - 2022
SP  - 104232
T2  - International Journal of Nursing Studies
TI  - The effectiveness of distraction as preoperative anxiety management technique in pediatric patients: A systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35367844
UR  - https://www.sciencedirect.com/science/article/pii/S002074892200061X?via%3Dihub
VL  - 130
ER  -
TY  - JOUR
AB  - **Objectives**
This systematic review and meta-analysis examines the efficacy of physical activity interventions in the reduction of antisocial behavior in children and adults. Several possible moderators, including study design, sample characteristics (age, proportion male, and sample type), control group, and outcome characteristics (type of activity, duration, frequency), were also investigated.

**Methods**
A literature search was performed in the following databases: PubMed, Ebsco/SportDiscus, Ebsco/APA PsycINFO, Ebsco/ERIC, Ebsco/Criminal Justice Abstracts, Embase.com, and Clarivate Analytics/Web of Science Core Collection from inception to June 2021. Studies were eligible if they reviewed the effect of chronic physical activity interventions on antisocial behavior compared to wait-list, no-exercise, or attention control samples. The following studies were excluded: animal studies, studies reporting on acute exercise, studies including yoga or mindfulness as the sole measure of physical activity, and studies including substance (ab)use and/or smoking as the only outcome measure. A random effects model was used to calculate pooled effect sizes. The risk of bias was assessed using the Cochrane risk-of-bias tool (version 2).

**Results**
The search yielded 29 studies, of which 20 were included in the meta-analysis. Results indicate a significant small-to-medium effect (g = - 0.26) with a 95% confidence interval ranging from - 0.48 to - 0.04 in favor of physical activity interventions. Significant moderators included type of control group, type of physical activity, and type of antisocial behavior, with larger effect sizes for comparisons with inactive control groups (g = - 0.31), interventions containing walking, jogging, or running as the main type of physical activity (g = - 0.87), and anger/hostility as an antisocial outcome measure (g = - 0.42).

**Conclusions**
Physical activity interventions may be a promising way to reduce antisocial behavior in children and adults. However, due to the overall high risk of bias in the included studies, more sound evaluation research is needed to better understand the functioning and to improve the possible implementation of physical activity interventions. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2023-17775-001
AU  - van
AU  - der
AU  - Sluys,
AU  - M.
AU  - Zijlmans,
AU  - J.
AU  - Ket,
AU  - J.
AU  - Marhe,
AU  - R.
AU  - Popma,
AU  - A.
AU  - Scherder,
AU  - E.
AU  - van
AU  - der
AU  - Laan,
AU  - P.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s11292-022-09536-8
L1  - internal-pdf://3524320498/van der Sluys-2022-The efficacy of physical ac.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Journal of Experimental Criminology
TI  - The efficacy of physical activity interventions in reducing antisocial behavior: A meta-analytic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc19&amp;AN=2023-17775-001
UR  - https://link.springer.com/content/pdf/10.1007/s11292-022-09536-8.pdf
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD), one of the most common neurodevelopmental disorders in children and adolescents, is typically managed with medications which are associated with negative side effects. Therefore, non-pharmacological treatments, such as physical activity, are an attractive option. The aim of this meta-analysis was to explore the effects of acute physical activity on cognition in children and adolescents with ADHD. A comprehensive search of three literature databases yielded 14 studies for inclusion. An overall meta-analysis was conducted alongside sub-group analyses for cognitive domain, physical activity characteristics, and timing of cognitive measurements. Results revealed a small beneficial effect of physical activity on cognitive function (SMD = 0.18, [0.12,0.25], p &lt; 0.01). Sub-group analyses revealed beneficial effects of physical activity on the domains of cognitive flexibility (SMD = 0.21, [0.09,0.32], p &lt; 0.01), attention (SMD = 0.20, [0.09,0.32], p = 0.001), and inhibitory control (SMD = 0.18, [0.03,0.33], p = 0.02), but not memory (p = 0.87). Cognitive benefits also differed depending on physical activity duration (&lt;10 min, p = 0.27; 11-20 min, SMD = 0.23, [0.14,0.31], p &lt; 0.01; &gt;20 min, SMD = 0.13, [-0.00,0.26], p = 0.05), and modality (running, SMD = 0.21, [0.12,0.29], p &lt; 0.01; &#039;other&#039;, SMD = 0.39, [0.18,0.61], p &lt; 0.01; cycling, p = 0.35), and the timing of cognitive measurement following physical activity (immediately, SMD = 0.17, [-0.01,0.35], p = 0.06; 2-10 min, SMD = 0.21, [0.12,0.30], p &lt; 0.01; &gt;10 min, SMD = 0.19, [-0.09,0.47], p = 0.19). Overall, physical activity has a positive acute effect on subsequent cognition in children and adolescents with ADHD, though effects may be domain specific and influenced by the duration and modality of physical activity. These findings have practical implications for those interested in using physical activity to enhance cognition in children and adolescents with ADHD. Copyright &copy; 2022 The Authors
AN  - 2019693389
AU  - Sibbick,
AU  - E.
AU  - Boat,
AU  - R.
AU  - Sarkar,
AU  - M.
AU  - Groom,
AU  - M.
AU  - Cooper,
AU  - S.
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.mhpa.2022.100469
L1  - internal-pdf://1720486421/1-s2.0-S175529662200031X-main.cleaned.pdf
PY  - 2022
T2  - Mental Health and Physical Activity
TI  - Acute effects of physical activity on cognitive function in children and adolescents with attention-deficit/hyperactivity disorder: A systematic review and meta-analysis
UR  - http://www.elsevier.com
UR  - https://www.sciencedirect.com/science/article/pii/S175529662200031X?via%3Dihub
VL  - 23 (no pagination)
ER  -
TY  - JOUR
AB  - **Background**
Several school‐based interventions are effective in improving child diet and physical activity, and preventing excessive weight gain, and tobacco or harmful alcohol use. However, schools are frequently unsuccessful in implementing such evidence‐based interventions.

**Objectives**
1. To evaluate the benefits and harms of strategies aiming to improve school implementation of interventions to address student diet, physical activity, tobacco or alcohol use, and obesity.

2. To evaluate the benefits and harms of strategies to improve intervention implementation on measures of student diet, physical activity, obesity, tobacco use or alcohol use; describe their cost or cost‐effectiveness; and any harms of strategies on schools, school staff or students.

**Search methods**
We used standard, extensive Cochrane search methods. The latest search was between 1 September 2016 and 30 April 2021 to identify any relevant trials published since the last published review.

**Selection criteria**
We defined &#039;Implementation&#039; as the use of strategies to adopt and integrate evidence‐based health interventions and to change practice patterns within specific settings. We included any trial (randomised controlled trial (RCT) or non‐randomised controlled trial (non‐RCT)) conducted at any scale, with a parallel control group that compared a strategy to implement policies or practices to address diet, physical activity, overweight or obesity, tobacco or alcohol use by students to &#039;no intervention&#039;, &#039;usual&#039; practice or a different implementation strategy.

**Data collection and analysis**
We used standard Cochrane methods. Given the large number of outcomes reported, we selected and included the effects of a single outcome measure for each trial for the primary (implementation) and secondary (student health behaviour and obesity) outcomes using a decision hierarchy. Where possible, we calculated standardised mean differences (SMDs) to account for variable outcome measures with 95% confidence intervals (CI). For RCTs, we conducted meta‐analyses of primary and secondary outcomes using a random‐effects model, or in instances where there were between two and five studies, a fixed‐effect model. The synthesis of the effects for non‐randomised studies followed the &#039;Synthesis without meta‐analysis&#039; (SWiM) guidelines.

**Main results**
We included an additional 11 trials in this update bringing the total number of included studies in the review to 38. Of these, 22 were conducted in the USA. Twenty-six studies used RCT designs. Seventeen trials tested strategies to implement healthy eating, 12 physical activity and six a combination of risk factors. Just one trial sought to increase the implementation of interventions to delay initiation or reduce the consumption of alcohol. All trials used multiple implementation strategies, the most common being educational materials, educational outreach and educational meetings.

The overall certainty of evidence was low and ranged from very low to moderate for secondary review outcomes.
Pooled analyses of RCTs found, relative to a control, the use of implementation strategies may result in a large increase in the implementation of interventions in schools (SMD 1.04, 95% CI 0.74 to 1.34; 22 RCTs, 1917 participants; low-certainty evidence). For secondary outcomes we found, relative to control, the use of implementation strategies to support intervention implementation may result in a slight improvement on measures of student diet (SMD 0.08, 95% CI 0.02 to 0.15; 11 RCTs, 16,649 participants; low-certainty evidence) and physical activity (SMD 0.09, 95% CI &minus;0.02 to 0.19; 9 RCTs, 16,389 participants; low-certainty evidence). The effects on obesity probably suggest little to no difference (SMD &minus;0.02, 95% CI &minus;0.05 to 0.02; 8 RCTs, 18,618 participants; moderate-certainty evidence). The effects on tobacco use are very uncertain (SMD &minus;0.03, 95% CIs &minus;0.23 to 0.18; 3 RCTs, 3635 participants; very low-certainty evidence). One RCT assessed measures of student alcohol use and found strategies to support implementation may result in a slight increase in use (odds ratio 1.10, 95% CI 0.77 to 1.56; P = 0.60; 2105 participants). Few trials reported the economic evaluations of implementation strategies, the methods of which were heterogeneous and evidence graded as very uncertain. A lack of consistent terminology describing implementation strategies was an important limitation of the review.

**Authors&#039; conclusions**
The use of implementation strategies may result in large increases in implementation of interventions, and slight improvements in measures of student diet, and physical activity. Further research is required to assess the impact of implementation strategies on such behavioural- and obesity-related outcomes, including on measures of alcohol use, where the findings of one trial suggest it may slightly increase student risk. Given the low certainty of the available evidence for most measures further research is required to guide efforts to facilitate the translation of evidence into practice in this setting.
AU  - Wolfenden,
AU  - L.
AU  - McCrabb,
AU  - S.
AU  - Barnes,
AU  - C.
AU  - O&#039;Brien,
AU  - K.
AU  - M.
AU  - Ng,
AU  - K.
AU  - W.
AU  - Nathan,
AU  - N.
AU  - K.
AU  - Sutherland,
AU  - R.
AU  - Hodder,
AU  - R.
AU  - K.
AU  - Tzelepis,
AU  - F.
AU  - Nolan,
AU  - E.
AU  - Williams,
AU  - C.
AU  - M.
AU  - Yoong,
AU  - S.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD011677.pub3
L1  - internal-pdf://3303266594/Wolfenden_et_al-2022-Cochrane_Database_of_Syst.pdf
PY  - 2022
T2  - Cochrane Database of Systematic Reviews
TI  - Strategies for enhancing the implementation of school‐based policies or practices targeting diet, physical activity, obesity, tobacco or alcohol use
ER  -
TY  - JOUR
AB  - BACKGROUND: There is an increasing demand to improve personal health and reduce the social burden in children with autism spectrum disorder (ASD). A comprehensive review of ASD interventions from the point of view of efficacy, safety, and compliance is needed. The purpose of this study was to evaluate the efficacy and safety of East Asian Herbal Medicine (EAHM) in the treatment of ASD. 

MATERIALS AND METHODS: Eleven databases (PubMed, Cochrane Library, CINAHL, EMBASE, KISS, RISS, OASIS, KCI, CNKI, Wanfang data, and CiNii) were searched from their respective inception to July 2021. A search was conducted by combining the keywords Autism Spectrum Disorder and Herbal medicine. We included a randomized controlled trial in which oral administration of EAHM was combined with conventional treatment for pediatric ASD patients. The primary outcomes were the clinical efficacy rate and the improvement in Childhood Autism Rating Scale (CARS) score. 

RESULTS: A total of 7 studies involving 462 children with ASD were included. The results suggest that EAHM as part of a combined therapy enhances the CARS score (MD[95% confidential interval]=4.47[5.89,3.05], p&lt;0.01) and the clinical efficacy rate (RR=1.31[1.14,1.51], p&lt;0.01) in comparison to the control group using only conventional therapy. Safety information was reported in 4 of the 7 included studies, and there were no adverse events or the difference in the incidence of side effects between the two groups was not significant. 

CONCLUSION: This meta-analysis shows that EAHM may improves the clinical efficacy rate and CARS score in children with ASD. However, in that the quality of the included studies is not generally high and the numbers are difficult to be considered sufficient, larger scale and rigorously designed randomized controlled trials need to be conducted to strengthen the evidence.
AN  - 35181230
AU  - Lee,
AU  - J.
AU  - H.
AU  - Jo,
AU  - H.
AU  - G.
AU  - Min,
AU  - S.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.explore.2022.02.001
L1  - internal-pdf://1014103487/East Asian Herbal Medicine Combined with-2022.pdf
PY  - 2022
SP  - 03
T2  - Explore: The Journal of Science &amp; Healing
TI  - East Asian Herbal Medicine Combined with Conventional Therapy for Children with Autism Spectrum Disorder: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35181230
UR  - https://www.sciencedirect.com/science/article/pii/S1550830722000040?via%3Dihub
VL  - 03
ER  -
TY  - JOUR
AB  - INTRODUCTION: Emotional dysregulation and irritability are common in individuals with autism spectrum disorder (ASD). We conducted the first meta-analysis assessing the efficacy of a broad range of pharmacological interventions for emotional dysregulation and irritability in ASD and predictors of response. 

METHOD: Following a pre-registered protocol (PROSPERO: CRD42021235779), we systematically searched multiple databases until 01/01/2021. We included placebo-controlled randomized controlled trials (RCTs) and evaluated the efficacy of pharmacological interventions and predictors of response for emotional dysregulation and irritability. We assessed heterogeneity using Q statistics and publication bias. We conducted sub-analyses and meta-regressions to identify predictors of response. The primary effect size was the Standardized Mean Difference. Quality of studies was assessed using the &quot;Cochrane Risk of Bias Tool&quot; (RoB2). 

RESULTS: 2,856 individuals with ASD in 45 studies were included, of which 26.7% of RCTs were at high risk of bias. Compared to placebo, antipsychotics (1.028, 0.824 to 1.232) and medications used to treat ADHD (0.471, 0.061 to 0.881) were significantly better than placebo in improving emotional dysregulation and irritability, while evidence of efficacy was not found for other drug classes (p&gt;0.05). Within individual medications, evidence of efficacy was found for aripiprazole (1.179, 0.838 to 1.520) and risperidone (1.074, 0.818 to 1.331). Increased rates of comorbid epilepsy (beta=-0.049, p=0.026) were associated with a lower efficacy. 

CONCLUSION: Some pharmacological interventions (particularly risperidone and aripiprazole) have proved efficacy for short-term treatment of emotional dysregulation and irritability in ASD and should be considered within a multimodal treatment plan, taking into account also tolerability profile and families&#039; preferences.
AN  - 35470032
AU  - Salazar
AU  - de
AU  - Pablo,
AU  - G.
AU  - Jorda,
AU  - C.
AU  - P.
AU  - Vaquerizo-Serrano,
AU  - J.
AU  - Moreno,
AU  - C.
AU  - Cabras,
AU  - A.
AU  - Arango,
AU  - C.
AU  - Hernandez,
AU  - P.
AU  - Veenstra-VanderWeele,
AU  - J.
AU  - Simonoff,
AU  - E.
AU  - Fusar-Poli,
AU  - P.
AU  - Santosh,
AU  - P.
AU  - Cortese,
AU  - S.
AU  - Parellada,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2022.03.033
L1  - internal-pdf://1201888860/Systematic Review and Meta-analysis_ Effi-2022.pdf
PY  - 2022
SP  - 22
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Systematic Review and Meta-analysis: Efficacy of Pharmacological Interventions for Irritability and Emotional Dysregulation in Autism Spectrum Disorder and Predictors of Response
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35470032
UR  - https://www.sciencedirect.com/science/article/pii/S0890856722001988?via%3Dihub
VL  - 22
ER  -
TY  - JOUR
AB  - **Background:** 
Implementation of interventions to treat child and adolescent mental health problems in schools could help fill the mental health care gap in low- and middle-income countries (LMICs). Most of the evidence available come from systematic reviews on mental health prevention and promotion, and there is less evidence on treatment strategies that can be effectively delivered in schools. The aim of this review was to identify what school-based interventions have been tested to treat children and adolescents in LMICs, and how effective they are. 

**Methods:** 
We conducted a systematic review including seven electronic databases. The search was carried out in October 2022. We included randomised or non-randomised studies that evaluated school-based interventions for children or adolescents aged 6-18 years living in LMICs and who had, or were at risk of developing, one or more mental health problems. 

**Results:** 
We found 39 studies with 43 different pairwise comparisons, treatment for attention-deficit and hyperactivity (ADHD), anxiety, depression, and posttraumatic stress disorder (PTSD), Conduct disorder (CD). Pooled SMD were statistically significant and showed that, overall, interventions were superior to comparators for PTSD (SMD = 0.61; 95% CI = 0.37-0.86), not statistically significant for anxiety (SMD = 0.11; 95% CI = -0.13 to 0.36), ADHD (SMD = 0.36; 95% CI = -0.15 to 0.87), and for depression (SMD = 0.80; 95% CI = -0.47 to 2.07). For CD the sample size was very small, so the results are imprecise. 

**Conclusion:** 
A significant effect was found if we add up all interventions compared to control, suggesting that, overall, interventions delivered in the school environment are effective in reducing mental health problems among children and adolescents. Systematic review registration: [https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=129376], identifier [CRD42019129376].
AN  - 36684024
AU  - Grande,
AU  - A.
AU  - J.
AU  - Hoffmann,
AU  - M.
AU  - S.
AU  - Evans-Lacko,
AU  - S.
AU  - Ziebold,
AU  - C.
AU  - de
AU  - Miranda,
AU  - C.
AU  - T.
AU  - McDaid,
AU  - D.
AU  - Tomasi,
AU  - C.
AU  - Ribeiro,
AU  - W.
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyt.2022.1012257
L1  - internal-pdf://0739479891/fpsyt-13-1012257.cleaned.pdf
PY  - 2022
SP  - 1012257
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Efficacy of school-based interventions for mental health problems in children and adolescents in low and middle-income countries: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36684024
VL  - 13
ER  -
TY  - JOUR
AB  - Despite widespread public interest in problematic gaming interventions, questions regarding the empirical status of treatment efficacy persist. We conducted pairwise and network meta-analyses based on 17 psychological intervention studies on excessive gaming (n = 745 participants). The pairwise meta-analysis showed that psychological interventions reduce excessive gaming more than the inactive control (standardized mean difference [SMD] = 1.70, 95% confidence interval [CI] 1.27 to 2.12) and active control (SMD = 0.88, 95% CI 0.21 to 1.56). The network meta-analysis showed that a combined treatment of Cognitive Behavioral Therapy (CBT) and Mindfulness was the most effective intervention in reducing excessive gaming, followed by a combined CBT and Family intervention, Mindfulness, and then CBT as a standalone treatment. Due to the limited number of included studies and resulting identified methodological concerns, the current results should be interpreted as preliminary to help support future research focused on excessive gaming interventions. Recommendations for improving the methodological rigor are also discussed.
AN  - WOS:000889945500053
AU  - Kim,
AU  - J.
AU  - Lee,
AU  - S.
AU  - Lee,
AU  - D.
AU  - Shim,
AU  - S.
AU  - Balva,
AU  - D.
AU  - Choi,
AU  - K.
AU  - H.
AU  - Chey,
AU  - J.
AU  - Shin,
AU  - S.
AU  - H.
AU  - Ahn,
AU  - W.
AU  - Y.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1038/s41598-022-24523-9
L1  - internal-pdf://0511354325/Kim-2022-Psychological treatments for excessiv.pdf
PY  - 2022
SP  - 13
T2  - Scientific Reports
TI  - Psychological treatments for excessive gaming: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000889945500053
UR  - https://www.nature.com/articles/s41598-022-24523-9.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - OBJECTIVE: 
To assess the effectiveness of non-pharmacological interventions for the treatment of autism spectrum disorder (ASD) in children.

DESIGN: 
Overview of systematic reviews (SRs).

PARTICIPANTS: Children aged 12 years and under with ASD. 

SEARCH METHODS: 
In October 2021, we searched Cochrane Central Register of Controlled Trials, MEDLINE, Embase, PsycINFO and Epistemonikos placing no restrictions on language or date of publication. 

INTERVENTIONS: 
17 non-pharmacological interventions compared with placebo, no-treatment (including waiting list) or other interventions (ie, usual care, as defined by the authors of each study). 

DATA COLLECTION AND ANALYSIS: 
We rated the methodological quality of the included SRs using A Measurement Tool to Assess Systematic Reviews (AMSTAR 2). We reported the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) certainty of the evidence (CoE) according to the analysis conducted by the authors of the included SRs. 

MAIN OUTCOME MEASURES: 
A multidisciplinary group of experts agreed on analysing nine critical outcomes evolving core and non-core ASD symptoms. 

PUBLIC AND PATIENT INVOLVEMENT STATEMENT: 
Organisations of parents of children with ASD participated in external revision of the final version of the report. 

RESULTS: 
We identified 52 reports that were within our scope, of which 48 were excluded for various reasons. After excluding less reliable SRs, we included four SRs. Non-pharmacological interventions (ie, Early Intensive Behavioural Intervention, Applied Behaviour Analysis, Picture Exchange Communication System and Naturalistic Developmental Behavioural Interventions) may have favourable effects on some core outcomes including language, social and functioning, play or daily living skills in children with ASD (with either no GRADE assessment, very low or low CoE). In addition, we identified a lack of report for other key outcomes in the included SRs (ie, restricted, repetitive behaviour; play and sensory processing). 

CONCLUSIONS: 
Synthesised evidence regarding the efficacy of non-pharmacological interventions for children with ASD is scarce. High-quality SRs addressing the variety of both non-pharmacological interventions and relevant outcomes are needed. Prospero registration number: Crd42020206535.
AN  - 35217568
AU  - Meza,
AU  - N.
AU  - Rojas,
AU  - V.
AU  - Escobar
AU  - Liquitay,
AU  - C.
AU  - M.
AU  - Perez,
AU  - I.
AU  - Aguilera
AU  - Johnson,
AU  - F.
AU  - Amarales
AU  - Osorio,
AU  - C.
AU  - Irarrazaval,
AU  - M.
AU  - Madrid,
AU  - E.
AU  - Franco,
AU  - J.
AU  - V.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/bmjebm-2021-111811
L1  - internal-pdf://2841268382/Non-pharmacological interventions for aut-2022.pdf
PY  - 2022
SP  - 25
T2  - BMJ Evidence based Medicine
TI  - Non-pharmacological interventions for autism spectrum disorder in children: an overview of systematic reviews
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35217568
UR  - https://ebm.bmj.com/content/early/2022/02/25/bmjebm-2021-111811
UR  - https://ebm.bmj.com/content/ebmed/early/2022/02/25/bmjebm-2021-111811.full.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - Remotely delivered parenting interventions are suitable to promote child well-being and development, in a context of social isolation, as our society faced due to COVID-19. The objective of this systematic review was to assess the effectiveness of remotely delivered parenting interventions for typically developing children on caregiver-child interaction and child development. We carried out a systematic search to find studies from the inception of the database to September 2021 on six electronic databases: MEDLINE, CINAHL, Embase, Scopus, Web of Science Core Collection and Regional Portal Information and Knowledge for Health (BVS), and gray literature. Eligible study designs were experimental and quasi-experimental studies. We included parenting interventions as long as they were remotely delivered and focused on typically developing children. Two outcomes were considered: caregiver-child interaction and child development. Three randomized controlled trials (RCT) and one quasi-experimental study met the inclusion criteria. Results from two RCT revealed positive, small-to-medium effects on child development. One study showed that the new intervention had a not inferior effect compared to the results achieved by the traditional support. Children who participated in the quasi-experimental study showed significant elevations in language ability. One study reported positive caregiver-child interaction results. There is insufficient evidence to draw definitive conclusions regarding the effectiveness of remotely delivered parenting interventions on child development due to the heterogeneity of participant profiles, mode of delivery, and assessment tools. The results suggest the need to develop future methodologically rigorous studies assessing the effectiveness of remotely delivered parenting interventions for typically developing children on caregiver-child interaction and child development.
AN  - 35615461
AU  - Solis-Cordero,
AU  - K.
AU  - Duarte,
AU  - L.
AU  - S.
AU  - Fujimori,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10826-022-02328-8
L1  - internal-pdf://0009648616/Effectiveness of Remotely Delivered Paren-2022.pdf
PY  - 2022
SP  - 1-11
T2  - Journal of Child &amp; Family Studies
TI  - Effectiveness of Remotely Delivered Parenting Programs on Caregiver-child Interaction and Child Development: a Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35615461
UR  - https://link.springer.com/content/pdf/10.1007/s10826-022-02328-8.pdf
ER  -
TY  - JOUR
AB  - **Background**
Pharmacological interventions for disordered and problem gambling have been employed in clinical practice. Despite the availability of several reviews of the efficacy of pharmacological interventions for disordered or problem gambling, few have employed systematic search strategies or compared different categories of pharmacological interventions. Systematic reviews of high‐quality evidence are therefore essential to provide guidance regarding the efficacy of different pharmacological interventions for disordered or problem gambling.

**Objectives**
The primary aims of the review were to: (1) examine the efficacy of major categories of pharmacological‐only interventions (antidepressants, opioid antagonists, mood stabilisers, atypical antipsychotics) for disordered or problem gambling, relative to placebo control conditions; and (2) examine the efficacy of these major categories relative to each other. 

**Search methods**
We searched the Cochrane Common Mental Disorders Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Ovid MEDLINE, Embase, and PsycINFO (all years to 11 January 2022).Selection criteriaWe included randomised trials evaluating a pharmacological intervention for the treatment of disordered or problem gambling. Eligible control conditions included placebo control groups or comparisons with another category of pharmacological intervention.

**Data collection and analysis**
We used standard methodological procedures, including systematic extraction of included study characteristics and results and risk of bias assessment. Our primary outcome was reduction in gambling symptom severity. Our secondary outcomes were reduction in gambling expenditure, gambling frequency, time spent gambling, depressive symptoms, anxiety symptoms, and functional impairment; and responder status. We evaluated treatment effects for continuous and dichotomous outcomes using standardised mean difference (SMD) and risk ratios (RR), respectively, employing random‐effects meta‐analyses. A minimum of two independent treatment effects were required for a meta‐analysis to be conducted (with only meta‐analytic findings reported in this abstract).

**Main results**
We included 17 studies in the review (n = 1193 randomised) that reported outcome data scheduled for end of treatment. Length of treatment ranged from 7 to 96 weeks.

Antidepressants: Six studies (n = 268) evaluated antidepressants, with very low to low certainty evidence suggesting that antidepressants were no more effective than placebo at post-treatment: gambling symptom severity (SMD &minus;0.32, 95% CI &minus;0.74 to 0.09, n = 225), gambling expenditure (SMD &minus;0.27, 95% CI &minus;0.60 to 0.06, n = 144), depressive symptoms (SMD &minus;0.19, 95% CI &minus;0.60 to 0.23, n = 90), functional impairment (SMD &minus;0.15, 95% CI &minus;0.53 to 0.22, n = 110), and responder status (RR 1.24, 95% CI 0.93 to 1.66, n = 268).

Opioid antagonists: Four studies (n = 562) evaluated opioid antagonists, with very low to low certainty evidence showing a medium beneficial effect of treatment on gambling symptom severity relative to placebo at post-treatment (SMD &minus;0.46, 95% CI &minus;0.74 to &minus;0.19, n = 259), but no difference between groups in responder status (RR 1.65, 95% CI 0.86 to 3.14, n = 562).

Mood stabilisers: Two studies (n = 71) evaluated mood stabilisers (including anticonvulsants), with very low certainty evidence suggesting that mood stabilisers were no more effective than placebo at post-treatment: gambling symptom severity (SMD &minus;0.92, 95% CI &minus;2.24 to 0.39, n = 71), depressive symptoms (SMD &minus;0.15, 95% CI &minus;1.14 to 0.83, n = 71), and anxiety symptoms (SMD &minus;0.17, 95% CI &minus;0.64 to 0.30, n = 71).

Atypical antipsychotics:Two studies (n = 63) evaluated the atypical antipsychotic olanzapine, with very low certainty evidence showing a medium beneficial effect of treatment on gambling symptom severity relative to placebo at post-treatment (SMD &minus;0.59, 95% CI &minus;1.10 to &minus;0.08, n = 63).

Comparative effectiveness: Two studies (n = 62) compared antidepressants with opioid antagonists, with very low certainty evidence indicating that antidepressants were no more effective than opioid antagonists on depressive symptoms (SMD 0.22, 95% CI &minus;0.29 to 0.72, n = 62) or anxiety symptoms (SMD 0.21, 95% CI &minus;0.29 to 0.72, n = 62) at post-treatment. Two studies (n = 58) compared antidepressants with mood stabilisers (including anticonvulsants), with very low certainty evidence indicating that antidepressants were no more effective than mood stabilisers on depressive symptoms (SMD 0.02, 95% CI &minus;0.53 to 0.56, n = 58) or anxiety symptoms (SMD 0.16, 95% CI &minus;0.39 to 0.70, n = 58) at post-treatment.

Tolerability and adverse events: Several common adverse effects were reported by participants receiving antidepressants (e.g. headaches, nausea, diarrhoea/gastrointestinal issues) and opioid antagonists (e.g. nausea, dry mouth, constipation). There was little consistency in the types of adverse effects experienced by participants receiving mood stabilisers (e.g. tiredness, headaches, concentration difficulties) or atypical antipsychotics (e.g. pneumonia, sedation, increased hypomania). Discontinuation of treatment due to these adverse events was highest for opioid antagonists (10% to 32%), followed by antidepressants (4% to 31%), atypical antipsychotics (14%), and mood stabilisers (13%).

**Authors&#039; conclusions**
This review provides preliminary support for the use of opioid antagonists (naltrexone, nalmefene) and atypical antipsychotics (olanzapine) to produce short-term improvements in gambling symptom severity, although a lack of available evidence precludes a conclusion regarding the degree to which these pharmacological agents can improve other gambling or psychological functioning indices. In contrast, the findings are inconclusive with regard to the effects of mood stabilisers (including anticonvulsants) in the treatment of disordered or problem gambling, and there is limited evidence to support the efficacy of antidepressants. However, these conclusions are based on very low to low certainty evidence characterised by a small number of included studies, high risk of bias, modest pooled sample sizes, imprecise estimates, moderate between-study heterogeneity, and exclusion of participants with psychiatric comorbidities. Moreover, there were insufficient studies to conduct meta-analyses on many outcome measures; to compare efficacy across and within major categories of interventions; to explore dosage effects; or to examine effects beyond post-treatment. These limitations suggest that, despite recommendations related to the administration of opioid antagonists in the treatment of disordered or problem gambling, pharmacological interventions should be administered with caution and with careful consideration of patient needs. A larger and more methodologically rigorous evidence base with longer-term evaluation periods is required before definitive conclusions can be drawn about the effectiveness and durability of pharmacological treatments for disordered or problem gambling.
AU  - Dowling,
AU  - N.
AU  - Merkouris,
AU  - S.
AU  - Lubman,
AU  - D.
AU  - Thomas,
AU  - S.
AU  - Bowden-Jones,
AU  - H.
AU  - Cowlishaw,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD008936.pub2
L1  - internal-pdf://1918771664/Dowling_et_al-2022-Cochrane_Database_of_System.pdf
PY  - 2022
T2  - Cochrane Database of Systematic Reviews
TI  - Pharmacological interventions for the treatment of disordered and problem gambling
ER  -
TY  - JOUR
AB  - **Objective:** 
The efficacy of medication and psychotherapy for adolescent depression is controversial, so we conducted a meta-analysis to evaluate the efficacy of combination therapy. 

**Methods:** 
We followed the PRISMA checklist in completing the meta-analysis. Relevant literature was searched in PubMed, Web of Science and Embase, Chinese databases CNKI and WanFang Data. We included the literature on the comparison of the fluoxetine plus psychotherapy or cognitive-behavioral therapy (CBT) and each treatment alone for adolescent depression published in 1980-2021. All statistical analyses were performed using Stata software. 

**Results:** 
After careful review, a total of 489 relevant articles were retrieved, and 13 studies were finally included. In comparison with the control group (fluoxetine alone), fluoxetine plus CBT achieved higher response rate (RR=1.12, 95% CI: 1.04, 1.21), lower incidence of adverse Reactions (RR=0.62,95% CI:0.40,0.96), lower proportion of suicide or self-injury (RR=0.94,95% CI:0.74,1.20), and lower one-year recurrence rate (RR=0.27, 95% CI: 0.16, 0.45). Before treatment, there were no significant differences in Hamilton Depression Scale score (HAMD), Children&#039;s Depression Rating Scale Revised (CDRS-R) score, and Clinical Global Impression (CGI) Severity score. After treatment, HAMD score (SMD=-1.01, 95% CI:-1.39,-0.63), CDRS-R score (SMD= -0.10,95% CI:-0.26,-0.07), and CGI score (SMD = -0.22, 95% CI: -0.54, -0.10) were significantly lower in the combined treatment group than in the control group. 

**Conclusion:** 
Adolescents simultaneously treated with fluoxetine and CBT had significantly reduced incidence of depressive symptoms, suicide or NSSI, adverse reactions, and one-year recurrence of symptoms, than adolescents treated with fluoxetine alone. This indicates fluoxetine plus CBT may be superior to fluoxetine alone for the clinical treatment of adolescent depression.
AN  - 36349346
AU  - Liu,
AU  - W.
AU  - Li,
AU  - G.
AU  - Wang,
AU  - C.
AU  - Yu,
AU  - M.
AU  - Zhu,
AU  - M.
AU  - Yang,
AU  - L.
DB  - Alerts 6_2022.enl
DO  - /10.2147/NDT.S367931
L1  - internal-pdf://1588777039/Liu-2022-Can Fluoxetine Combined with Cognitiv.pdf
PY  - 2022
SP  - 2543-2557
T2  - Neuropsychiatric Disease &amp; Treatment
TI  - Can Fluoxetine Combined with Cognitive Behavioral Therapy Reduce the Suicide and Non-Suicidal Self-Injury Incidence and Recurrence Rate in Depressed Adolescents Compared with Fluoxetine Alone? A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36349346
UR  - https://www.dovepress.com/getfile.php?fileID=85132
VL  - 18
ER  -
TY  - JOUR
AB  - PURPOSE: 
Adolescence is a sensitive period for developing mental health problems. Interventions targeting emotion regulation have shown promising transdiagnostic effects for this group, but optimization efforts are called for. In the current study, we used an element-based approach to identify potentially active ingredients in interventions measuring emotion regulation, to guide further optimization. 

METHODS: 
We coded practice elements in 30 studies based on a systematic review of mental health interventions measuring emotion regulation in adolescents (N = 2,389 participants, mean age 13-17 years). Using a three-level modeling approach, we then investigated the difference in effect on emotion regulation between studies of interventions with and without these practice elements. 

RESULTS: 
We identified 75 practice elements and 15 element categories used in the included interventions. Results showed significantly stronger effects on emotion regulation when interventions included the practice elements Setting goals for treatment (difference in d = 0.40, 95% CI [0.09, 0.70], p = .012) and Psychoeducation about acceptance (difference in d = 0.58, 95% CI [0.09, 1.07], p = .021). Furthermore, a total of 11 elements and four overall categories were identified as potentially active ingredients, based on an effect size difference of &gt; 0.20 between interventions with and without the elements. 

CONCLUSION: 
The results can direct experimental research into the selection of practices that are most likely key to mechanisms of change in interventions addressing emotion regulation for adolescents. The challenge of measuring emotion regulation is discussed.
AN  - 35987830
AU  - Helland,
AU  - S.
AU  - S.
AU  - Mellblom,
AU  - A.
AU  - V.
AU  - Kjobli,
AU  - J.
AU  - Wentzel-Larsen,
AU  - T.
AU  - Espenes,
AU  - K.
AU  - Engell,
AU  - T.
AU  - Kirkoen,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10488-022-01213-2
L1  - internal-pdf://3274603938/Helland-2022-Elements in Mental Health Interve.pdf
PY  - 2022
SP  - 20
T2  - Administration &amp; Policy in Mental Health
TI  - Elements in Mental Health Interventions Associated with Effects on Emotion Regulation in Adolescents: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35987830
UR  - https://link.springer.com/content/pdf/10.1007/s10488-022-01213-2.pdf
VL  - 20
ER  -
TY  - JOUR
AB  - **Objective**
If a psychotherapeutic intervention has the capacity to produce positive change, the &quot;deterioration effect&quot; theory holds that it must also have the potential for negative effects. However, the definition, measurement, and reporting of unwanted events in psychotherapy is a topic of ongoing discussion. At present this area is under-explored in interventions for anorexia nervosa (AN), a severe mental illness associated with high medical and psychiatric risks. The aim of this article was to undertake a systematic review of published randomized controlled trials (RCTs) evaluating psychotherapeutic interventions for AN, and to assess how unwanted events were defined, monitored, and reported alongside the trial&#039;s key findings. 

**Method**
Using a systematic review methodology, this article identified 23 RCTs through database searches meeting eligibility criteria. Results are presented using a narrative summary approach. 

**Results**
Unwanted event reporting varied widely, both regarding definitions of key unwanted events (such as non-compliance or symptom deterioration) and in the amount of detail captured in each paper. 

**Discussion**
The review identified two key issues: firstly, a lack of consistent definitions and unclear causality made it difficult to distinguish between unwanted events, and adverse events caused by the interventions. Secondly, it highlighted the difficulty of defining unwanted events where different studies have different populations and goals. Recommendations are made around how the area of defining, monitoring, and reporting unwanted events in RCTs for AN can be taken forward. 

**Public Significance**
Whilst psychotherapies can be effective in treating mental health conditions, negative or unwanted events can sometimes occur. This review explored how RCTs examining psychotherapy for AN report how they monitor the safety of participants, and how they report unwanted events. We found that the reporting was often inconsistent or hard to interpret, and we have made recommendations for how this can be improved in the future.
AN  - WOS:000943362400001
AU  - Kinnaird,
AU  - E.
AU  - Nicholson,
AU  - M.
AU  - Thomas,
AU  - A.
AU  - Cooper,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/eat.23926
L1  - internal-pdf://2068166818/Kinnaird-Systematic review_ Exploring the moni.pdf
PY  - 2022
SP  - 18
T2  - International Journal of Eating Disorders
TI  - Systematic review: Exploring the monitoring and reporting of unwanted events in psychotherapy trials for anorexia nervosa
UR  - &lt;Go to ISI&gt;://WOS:000943362400001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eat.23926?download=true
ER  -
TY  - JOUR
AB  - OBJECTIVE: No synthesis of the Australian evidence regarding targeted prevention and early intervention for mental health concerns among young children exists. This review aimed to (1) describe the types of targeted community-based mental health programmes evaluated in Australia to support children aged 1-9 years exhibiting internalising and/or externalising symptoms and (2) examine their impact on children&#039;s internalising and externalising symptoms and disorder diagnosis. 

METHOD: A systematic review and meta-analysis was conducted (PROSPERO: CRD42021255257). Four databases (PsycINFO, PsycArticles, MEDLINE and CINAHL) were searched for Australian studies published in the past 10 years that quantitatively evaluated the impact of a targeted programme on children&#039;s mental health. The National Institute of Health Quality Assessment Tools were used to evaluate the study quality. 

RESULTS: Forty-two studies were included; the majority (67%) were medium quality. The mean sample size was 142 (SD = 170), children&#039;s average age was 5.78 years (SD = 2.44) and 58% were male. Aboriginal and Torres Strait Islander children were underrepresented. Studies evaluated 16 programmes that targeted (1) externalising symptoms (n = 20 studies, n = 6 programmes), (2) internalising symptoms (n = 14 studies, n = 7 programmes) or (3) both, termed transdiagnostic programmes (n = 8 studies, n = 3 programmes). Externalising programmes achieved a significant moderate mean reduction in externalising behaviours (standardised mean differences = -0.56), internalising programmes yielded a small mean improvement in anxiety symptoms (standardised mean differences = -0.25) and 57% reduced odds of anxiety disorder diagnosis. Evidence supporting transdiagnostic programmes was inconclusive. 

CONCLUSION: Parenting-focused programmes targeting young children&#039;s internalising or externalising behaviours have the largest local evidence base supporting their effectiveness. Limitations include a lack of engagement with fathers, triangulation of outcomes, homogeneity and implementation reporting. Greater implementation and evaluation of community-driven integrated and systemic approaches that identify, engage and support Australia&#039;s most disadvantaged cohorts of young children and their families are needed.
AN  - 36113092
AU  - Savaglio,
AU  - M.
AU  - Yap,
AU  - M.
AU  - B.
AU  - O&#039;Donnell,
AU  - R.
AU  - Skouteris,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/00048674221124506
L1  - internal-pdf://2932595172/00048674221124506.cleaned.pdf
PY  - 2022
SP  - 48674221124506
T2  - Australian &amp; New Zealand Journal of Psychiatry
TI  - Targeted community-based programmes for children&#039;s mental health: A systematic review and meta-analysis of the Australian literature
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36113092
ER  -
TY  - JOUR
AB  - Cognitive control training has gained traction as an intervention for reducing anxiety and depression vulnerability in adults. There are, however, a limited number of studies investigating such training interventions for reducing symptomology of anxiety and depression in children and adolescents. 

Thus, we aimed to provide a robust review and qualitative synthesis of the available research in young people. Twelve articles met the inclusion criteria, and all were randomised control trials. Evidence of the efficacy of cognitive control training for relief of symptoms are reported separately for anxiety, depression, and other related psychological factors, and on the basis of type of cognitive control training paradigm.

A lack of standardisation in relation to type of intervention, duration and context, outcome measures and population was observed. Results are discussed in terms of these variations and recommendations for future research are provided.
AN  - 34983006
AU  - Edwards,
AU  - E.
AU  - J.
AU  - Zec,
AU  - D.
AU  - Campbell,
AU  - M.
AU  - Hoorelbeke,
AU  - K.
AU  - Koster,
AU  - E.
AU  - H.
AU  - W.
AU  - Derakshan,
AU  - N.
AU  - Wynne,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2021.12.108
L1  - internal-pdf://1901434431/Cognitive control training for children w-2022.pdf
PY  - 2022
SP  - 158-171
T2  - Journal of Affective Disorders
TI  - Cognitive control training for children with anxiety and depression: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34983006
VL  - 300
ER  -
TY  - JOUR
AB  - **Objectives:** 
While long-lasting antipsychotics (LLA) were specifically developed to address the problem of adherence in patients with chronic psychiatric disorders, their role in pediatric populations is not clear. 

**Methods:** 
To document the efficacy, tolerance, and acceptance of LLAs in children and adolescents, a literature search was conducted using several databases for published studies (PubMed, PsycINFO) from January 1965 to December 2020. Twenty-two studies were identified (16 case reports/series, 3 open label studies, 2 controlled studies, and 1 retrospective analysis of national database). 

**Results:** 
Demographic features were widely heterogeneous across studies (total N = 480, 58% male, mean age = 15.0 +/- 1.8). Case reports/series presented positive therapeutic outcomes in noncompliant youths with severe mental illness. Three open-label one-arm studies supported the clinical efficacy of risperidone long-acting injection in patients previously stabilized with oral risperidone. One study showed lower clinical symptoms and higher functioning at 12 months in youths treated for an acute psychotic episode with paliperidone palmitate compared to oral risperidone. The types and rates of side effects of LLA were comparable to those observed for oral antipsychotics. Two studies suggested better metabolic and neurological tolerance of LLA compared to an oral form. Preliminary evidence supported a satisfactory level of treatment satisfaction in patients treated with LLA and their families, while concerns were raised regarding practical administration in outpatient services. However, the average quality of the evidence based on the RoB2 tool was low. 

**Conclusions:** 
The level of evidence was low for the efficacy of LLA in pediatric populations and very low for the tolerance and acceptance. It concerned mostly the effect of risperidone long-acting injection in adolescents with psychotic disorders. Randomized maintenance clinical trials using noninferiority analysis would be more appropriate for further research.
AN  - 35613381
AU  - Benarous,
AU  - X.
AU  - Cottin,
AU  - G.
AU  - Lahaye,
AU  - H.
AU  - de
AU  - la
AU  - Riviere,
AU  - S.
AU  - G.
AU  - Guile,
AU  - J.
AU  - M.
AU  - Speranza,
AU  - M.
AU  - Bonnot,
AU  - O.
AU  - Cohen,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1089/cap.2021.0124
L1  - internal-pdf://3656847151/Efficacy, Tolerability, and Acceptance of-2022.pdf
PY  - 2022
SP  - 25
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Efficacy, Tolerability, and Acceptance of Long-Lasting Antipsychotics in Children and Adolescents: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35613381
UR  - https://www.liebertpub.com/doi/10.1089/cap.2021.0124
UR  - https://www.liebertpub.com/doi/pdf/10.1089/cap.2021.0124?download=true
VL  - 25
ER  -
TY  - JOUR
AB  - **Background:** 
Posttraumatic stress disorder (PTSD) is common among children and adolescents who have experienced traumatic events. Exposure therapy (ET) has been shown to be effective in treating PTSD in adults. However, its efficacy remains uncertain in children and adolescents. Aim(s): To evaluate the efficacy and acceptability of ET in children and adolescents with PTSD. 

**Method(s):** 
We searched PubMed, EMBASE, Cochrane, Web of Science, PsycINFO, CINAHL, ProQuest, LILACS, and international trial registries for randomized controlled trials (RCTs) assessed ET in children and adolescents (aged &lt;=18 years) with PTSD up to August 31, 2020. The primary outcomes were efficacy (the endpoint score from PTSD symptom severity rating scales) and acceptability (all-cause discontinuation), secondary outcomes included efficacy at follow-up (score from PTSD scales at the longest point of follow-up), depressive symptoms (end-point score on depressive symptom severity rating scales) and quality of life/social functioning (end-point score on quality of life/social functioning rating scales). This study was registered with PROSPERO (CRD42020150859). 

**Result(s):** 
A total of 6 RCTs (278 patients) were included. The results showed that ET was statistically more efficacious than control groups (standardized mean differences [SMD]: - 0.47, 95% confidence interval [CI]: - 0.91 to - 0.03). In subgroup analysis, exposure therapy was more efficacious for patients with single type of trauma (SMD: - 1.04, 95%CI: - 1.43 to - 0.65). Patients with an average age of 14 years and older, ET was more effective than the control groups (SMD: - 1.04, 95%CI: - 1.43 to - 0.65), and the intervention using prolonged exposure therapy (PE) (SMD: - 1.04, 95%CI: - 1.43 to - 0.65) was superior than control groups. Results for secondary outcomes of efficacy at follow-up (SMD: - 0.64, 95%CI: - 1.17 to - 0.10) and depressive symptoms (SMD: - 0.58, 95%CI: - 0.93 to - 0.22) were similar to the previous findings for efficacy outcome. No statistically significant effects for acceptability and quality of life/social functioning were found. 

**Conclusion(s):** 
ET showed superiority in efficacy at post-treatment/follow-up and depressive symptoms improvement in children and adolescents with PTSD. Patients with single type of trauma may benefit more from ET. And ET is more effective in patients 14 years or older. Moreover, PE could be a better choice. Copyright &copy; 2022, The Author(s).
AN  - 2015600955
AU  - Huang,
AU  - T.
AU  - Li,
AU  - H.
AU  - Tan,
AU  - S.
AU  - Xie,
AU  - S.
AU  - Cheng,
AU  - Q.
AU  - Xiang,
AU  - Y.
AU  - Zhou,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12888-022-03867-6
L1  - internal-pdf://4147007993/The efficacy and acceptability of exposur-2022.pdf
PY  - 2022
T2  - BMC Psychiatry
TI  - The efficacy and acceptability of exposure therapy for the treatment of post-traumatic stress disorder in children and adolescents: a systematic review and meta-analysis
UR  - https://bmcpsychiatry.biomedcentral.com/
UR  - https://bmcpsychiatry.biomedcentral.com/track/pdf/10.1186/s12888-022-03867-6.pdf
VL  - 22(1) (no pagination)
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Postpartum depression (PPD) is a public health problem that has significant adverse effects on mothers, couple&#039;s relationships, newborn neurodevelopment, and child emotional and cognitive development. This study reviewed the effectiveness of telemedicine interventions in postparturient women with postpartum depression. AIMS: To evaluate the effectiveness of telemedicine intervention in women with postpartum depression. 

METHODS: 
Cochrane Library, PubMed, EMBASE, Web of Science, CINAHL, and PsycINFO were searched for relevant articles published between 2003 and March 2021. We also manually reviewed the reference lists of the retrieved articles. The present study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The risk of bias for individual studies was evaluated according to the Cochrane Handbook. RevMan 5.4 software was used to carry out the meta-analysis. 

RESULTS: 
The meta-analysis included 20 randomized controlled trials with a total of 3252 patients. The results demonstrated that telemedicine was an effective intervention for treating PPD and anxiety and for improving functional impairment in women during their postpartum period. 

LINKING EVIDENCE TO ACTION: 
This meta-analysis provided evidence that telemedicine was an effective intervention for treating PPD in women. Telemedicine also has significant effects on anxiety and improved functional impairment in women during their postpartum period. Our findings may provide accurate evidence-based guidance for postpartum women&#039;s mental health management. In the future, more high-quality studies are required for verifying these results.
AN  - 35349219
AU  - Liu,
AU  - X.
AU  - Huang,
AU  - S.
AU  - Hu,
AU  - Y.
AU  - Wang,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/wvn.12576
L1  - internal-pdf://3445957398/The effectiveness of telemedicine interve-2022.pdf
PY  - 2022
SP  - 29
T2  - Worldviews on Evidence Based Nursing
TI  - The effectiveness of telemedicine interventions on women with postpartum depression: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35349219
VL  - 29
ER  -
TY  - JOUR
AB  - **Background:** 
Among minors, posttraumatic stress symptoms (PTSS) are a common consequence of traumatic events requiring trauma-focused treatment. 

**Objective(s):** 
This meta-analysis quantified treatment effects of trauma-focused cognitive behavioral therapy (TF-CBT) with PTSS as primary outcome and symptoms of depression, anxiety, and grief as secondary outcomes. 

**Participants and setting:** 
Inclusion criteria for individual settings: (1) patients aged between 3 and 21, (2) at least one traumatic event, (3) minimum 8 sessions of (4) TF-CBT according to Cohen, Mannarino and Deblinger (2006, 2017), (5) a quantitative PTSS measure at pre- and post-treatment, (6) original research only. Inclusion criteria for group settings: had to involve (1) psychoeducation, (2) coping strategies, (3) exposure, (4) cognitive processing/restructuring, (5) contain some reference to the manual and no minimum session number was required. 

**Method(s):** 
Searched databases were PsychInfo, MEDLINE, Cochrane Library, PTSDPubs, PubMed, Web of Science, and OpenGrey. Result(s): 4523 participants from 28 RCTs and 33 uncontrolled studies were included. TF-CBT showed large improvements across all outcomes from pre- to post-treatment (PTSS: g = 1.14, CI 0.97-1.30) and favorable results compared to any control condition including wait-list, treatment as usual, and active treatment at post-treatment (PTSS: g = 0.52, CI 0.31-0.73). Effects were more pronounced for group settings. We give pooled estimates adjusted for risk of bias and publication bias, which initially limited the quality of the analyzed data. 

**Conclusion(s):** 
TF-CBT is an effective treatment for pediatric PTSS as well as for depressive, anxiety, and grief symptoms. It is superior to control conditions, supporting international guidelines recommending it as a first-line treatment. Copyright &copy; 2022 Elsevier Ltd
AN  - 2020320810
AU  - Thielemann,
AU  - J.
AU  - F.
AU  - B.
AU  - Kasparik,
AU  - B.
AU  - Konig,
AU  - J.
AU  - Unterhitzenberger,
AU  - J.
AU  - Rosner,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.chiabu.2022.105899
L1  - internal-pdf://2929651380/1-s2.0-S0145213422004331-main.cleaned.pdf
PY  - 2022
T2  - Child Abuse and Neglect
TI  - A systematic review and meta-analysis of trauma-focused cognitive behavioral therapy for children and adolescents
UR  - https://www.elsevier.com/locate/chiabuneg
UR  - https://www.sciencedirect.com/science/article/pii/S0145213422004331?via%3Dihub
VL  - 134 (no pagination)
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis examined interventions targeting play skills of children with autism spectrum disorder (ASD) involving typically developing (TD) peers. The objectives of this work are to (a) identify and describe the characteristics and components of interventions aimed at improving play skills in children with ASD and their TD peers, (b) examine the role of peers in interventions, (c) evaluate intervention effects, and (d) identify potential moderating variables that may influence intervention outcomes. Twenty single-case experimental design (SCED) studies published between 2000 and 2020 were included and summarized. The majority of interventions produced significant effects, further supporting the inclusion of TD peers in interventions targeting play skills for children with ASD. Recommendations for future research and practice are discussed.
AN  - WOS:000850394700002
AU  - Fedewa,
AU  - M.
AU  - Watkins,
AU  - L.
AU  - Barnard-Brak,
AU  - L.
AU  - Akemoglu,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40489-022-00343-5
L1  - internal-pdf://1307190071/Fedewa-A Systematic Review and Meta-Analysis o.pdf
PY  - 2022
SP  - 23
T2  - Review Journal Of Autism And Developmental Disorders
TI  - A Systematic Review and Meta-Analysis of Single Case Experimental Design Play Interventions for Children with Autism and Their Peers
UR  - &lt;Go to ISI&gt;://WOS:000850394700002
UR  - https://link.springer.com/article/10.1007/s40489-022-00343-5
UR  - https://link.springer.com/content/pdf/10.1007/s40489-022-00343-5.pdf
ER  -
TY  - JOUR
AB  - OBJECTIVE: This systematic review aimed to summarise the effects of cognitive-behavioural therapy on psychological, physical and social outcomes of children with cancer without limitations on publication date. 

METHODS: Thirteen English and seven Chinese electronic databases were searched from April to June 2021. Randomised control trials, quasi-experimental studies, pre-test post-test studies with a control group, factorial or cross-over designs that included children &lt;=18 years old and during various stages of the cancer trajectory, who have received cognitive-behavioural therapy, and reported (anxiety, depression, stress, quality of life, self-efficacy, fatigue, pain, behavioural distress, anger, and/or academic performance) were included. 

RESULTS: Eight studies with quality of evidence ranging from low to high risk of bias were included. The results show cognitive-behavioural therapy has favourable effects on anxiety, depression, pain and behavioural distress. The meta-analysis also show that it reduces anxiety (SMD = -0.89, 95% CI (-1.45, -0.32), p &lt; 0.002), depression (SMD = -0.90, 95% CI (-1.40, -0.39), p &lt; 0.0005), and pain (SMD = -0.56, 95% CI (-1.04, -0.08), p &lt; 0.002). It also has a favourable effect on stress, anger and self-efficacy, though the results are drawn from a single study. 

CONCLUSION: Cognitive-behavioural therapy has the potential to reduce anxiety, depression and pain for children with cancer. It also shows promise in reducing behavioural distress. Although effects on stress, anger, and self-efficacy have been found to be significant, there have been limited studies on these aspects of functioning and more research is needed. The findings are drawn from heterogeneous participants and interventions, thus emphasising the need to conduct well-designed intervention studies, including cancer survivors.
AN  - 35378435
AU  - Melesse,
AU  - T.
AU  - G.
AU  - Chau,
AU  - J.
AU  - P.
AU  - C.
AU  - Nan,
AU  - M.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jpsychores.2022.110805
L1  - internal-pdf://0346511660/Effects of cognitive-behavioural therapy-2022.pdf
PY  - 2022
SP  - 110805
T2  - Journal of Psychosomatic Research
TI  - Effects of cognitive-behavioural therapy on psychological, physical and social outcomes of children with cancer: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35378435
UR  - https://www.sciencedirect.com/science/article/pii/S0022399922000903?via%3Dihub
VL  - 157
ER  -
TY  - JOUR
AB  - This meta-analysis review compared eye movement desensitization and reprocessing and cognitive behavior therapy efficacy in reducing post-traumatic stress disorder (PTSD), anxiety, and depression symptoms.

 A systematic search for articles published between 2010 and 2020 was conducted using five databases. The RevMan software version 5 was used. Out of 671 studies, 8 fulfilled the inclusion criteria and were included in this meta-analysis. 

Three studies reported that eye movement desensitization and reprocessing reduced depression symptoms better than cognitive behavior therapy in both children, adolescents, and adults (SDM (95% CI) = -2.43 (-3.93--0.94), p = 0.001). In three other studies, eye movement desensitization and reprocessing were shown to reduce anxiety in children and adolescents better than cognitive behavior therapy (SDM (95% CI) = -3.99 (-5.47--2.52), p &lt; 0.001).

In terms of reducing PTSD symptoms, eye movement desensitization and reprocessing and cognitive behavior therapy did not demonstrate any statistically significant differences (SDM (95% CI) = -0.14 (-0.48-0.21), p = 0.44). There was no statistically significant difference at the three-month follow-up and at the six-month follow-up for depression (p = 0.31), anxiety (p = 0.59), and PTSD (p = 0.55). We recommend randomized trials with larger samples and longer follow-up times in the future.
AD  - Hudays, Ali. Community, Psychiatric and Mental Health Nursing Department, College of Nursing, King Saud University, Riyadh 11543, Saudi Arabia.Gallagher, Robyn. Charles Perkins Centre, Faculty of Medicine and Health, The University of Sydney, Sydney 2050, Australia.Hazazi, Ahmed. Department of Public Health, Faculty of Health Science, Saudi Electronic University, Riyadh 13316, Saudi Arabia.Arishi, Amal. Medical Surgical Department, College of Nursing, King Saud University, Riyadh 11543, Saudi Arabia.Bahari, Ghareeb. Nursing Administration and Education Department, College of Nursing, King Saud University, Riyadh 11543, Saudi Arabia.
AN  - 36554717
AU  - Hudays,
AU  - A.
AU  - Gallagher,
AU  - R.
AU  - Hazazi,
AU  - A.
AU  - Arishi,
AU  - A.
AU  - Bahari,
AU  - G.
DA  - Dec 15
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/ijerph192416836
DP  - Ovid Technologies
J2  - Int J Environ Res Public Health
KW  - Child
KW  - Adult
KW  - Adolescent
KW  - Humans
KW  - Stress Disorders, Post-Traumatic/th [Therapy]
KW  - Stress Disorders, Post-Traumatic/px [Psychology]
KW  - *Stress Disorders, Post-Traumatic
KW  - Eye Movements
KW  - *Cognitive Behavioral Therapy
KW  - Anxiety Disorders/th [Therapy]
KW  - *Eye Movement Desensitization Reprocessing
KW  - Treatment Outcome
L1  - internal-pdf://1201099457/Hudays-2022-Eye Movement Desensitization and R.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
Review
N1  - Using Smart Source ParsingDecHudays, AliGallagher, RobynHazazi, AhmedArishi, AmalBahari, Ghareeb16836
PY  - 2022
SP  - 15
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Eye Movement Desensitization and Reprocessing versus Cognitive Behavior Therapy for Treating Post-Traumatic Stress Disorder: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36554717
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36554717&amp;id=doi:10.3390%2Fijerph192416836&amp;issn=1660-4601&amp;isbn=&amp;volume=19&amp;issue=24&amp;spage=&amp;pages=&amp;date=2022&amp;title=International+Journal+of+Environmental+Research+%26+Public+Health+%5BElectronic+Resource%5D&amp;atitle=Eye+Movement+Desensitization+and+Reprocessing+versus+Cognitive+Behavior+Therapy+for+Treating+Post-Traumatic+Stress+Disorder%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Hudays&amp;pid=%3Cauthor%3EHudays+A%3C%2Fauthor%3E%3CAN%3E36554717%3C%2FAN%3E%3CDT%3EMeta-Analysis%3C%2FDT%3E
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-19-16836/article_deploy/ijerph-19-16836.pdf?version=1671088599
VL  - 19
ER  -
TY  - JOUR
AB  - BACKGROUND: 
The United States Food and Drug Administration has approved drugs that address only autism-related symptoms rather than the underlying impairments. N-Methyl-D-Aspartate receptor antagonists have recently emerged as a promising treatment option for a variety of neurologic and developmental problems, including autism. AIMS: To review (systematically), for the first time, the medical literature that explores the safety in and efficacy of memantine in autism. 

METHODS AND PROCEDURES: 
A comprehensive electronic search for relevant randomized controlled trials was conducted in four databases. Using RevMan software, we extracted and pooled data as a risk ratio (RR) or normalized mean differences in an inverse variance strategy. 

RESULTS: 
This systematic review and meta-analysis includes five trials. There was no difference in enhancing social responsiveness when compared to placebo, though memantine lowered the likelihood of anxiety (RR = 0.25; 95% Confidence interval: [0.07; 0.87], p = 0.03). However, memantine aggravated impulsive behaviors. Additionally, in another trial that compared memantine added to risperidone versus risperidone added to placebo, memantine was found to be effective and safe. 

CONCLUSION: 
Memantine showed safety in reducing acute symptoms of anxiety and other symptoms encountered in pediatric patients with autism spectrum disorders. However, memantine does not improve the core symptoms of autism. Nevertheless, further long-term trials are needed to explore its potential efficacy.
AN  - 35315131
AU  - Elnaiem,
AU  - W.
AU  - Benmelouka,
AU  - A.
AU  - Y.
AU  - Elgendy,
AU  - A.
AU  - M.
AU  - N.
AU  - Abdelgalil,
AU  - M.
AU  - S.
AU  - Brimo
AU  - Alsaman,
AU  - M.
AU  - Z.
AU  - Mogheeth,
AU  - A.
AU  - Ali,
AU  - M.
AU  - M.
AU  - Yousof,
AU  - S.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/hup.2841
L1  - internal-pdf://1927951785/Evaluation of memantine&#039;s efficacy and sa-2022.pdf
PY  - 2022
SP  - e2841
T2  - Human Psychopharmacology
TI  - Evaluation of memantine&#039;s efficacy and safety in the treatment of children with autism spectrum disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35315131
ER  -
TY  - JOUR
AB  - The present systematic review aimed to investigate the methodological quality and the effects of fundamental motor skills and physical activity interventions on cognitive and academic skills in typically developing 3 to 7-year-old children. 

The review was conducted and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. A literature search was carried out in April 2020 using seven electronic databases. The methodological quality of the studies was assessed with the Effective Public Health Practice Project (EPHPP) Quality Assessment Tool. Cohen&#039;s d effect size calculations and post hoc power analyses were conducted for the included studies. 

A total of 35 studies, representing 2472 children met the inclusion criteria. Two of the studies demonstrated a strong methodological quality, while 24 were considered as methodologically weak. The majority (71%) of the included studies demonstrated the beneficial effects of the intervention on cognitive and academic skills. The most evidence was found for executive functions, language, and numeracy, and the effects were largest in enhancing memory. The effects were larger on cognitive and academic skills in the combined interventions compared to only fundamental motor skill and physical activity interventions, while fundamental motor skill interventions had larger effects than physical activity interventions. 

These findings indicate that it may be possible to support typically developing preschoolers&#039; cognitive and academic learning with fundamental motor skill and physical activity interventions. However, most of the studies in this field have a weak methodological quality and thus, the presented evidence was considered weak in nature. Copyright &copy; 2021 The Authors
AN  - 2016341237
AU  - Jylanki,
AU  - P.
AU  - Mbay,
AU  - T.
AU  - Hakkarainen,
AU  - A.
AU  - Saakslahti,
AU  - A.
AU  - Aunio,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ypmed.2021.106948
L1  - internal-pdf://2107939523/The effects of motor skill and physical a-2022.pdf
PY  - 2022
T2  - Preventive Medicine
TI  - The effects of motor skill and physical activity interventions on preschoolers&#039; cognitive and academic skills: A systematic review
UR  - http://www.elsevier.com/inca/publications/store/6/2/2/9/3/4/index.htt
VL  - 155 (no pagination)
ER  -
TY  - JOUR
AB  - **Background** 
Eating disorders (EDs) and high body mass index (BMI) are two important public health issues with significant health and cost impacts. The aim of this systematic review and meta-analysis was to establish whether interventions are effective in preventing both issues. 

**Methods** 
Electronic databases were searched up to 10 May 2021. Studies were included if they were randomised or quasi-randomised controlled trials that evaluated a preventive intervention (regardless of its aim to prevent ED, high BMI or both) and reported both EDs and BMI-related outcomes. Both narrative synthesis and meta-analysis were used to synthesise the results. Publication bias was also investigated. 

**Results** 
Fifty-four studies were included for analysis. The primary aim of the studies was ED prevention (n = 23), high BMI prevention (n = 21) and both ED and high BMI prevention (n = 10). Meta-analysis results indicated that preventive interventions had a significant effect on several ED outcomes including dieting, shape and weight concerns, body dissatisfaction, negative affect, eating disorder symptoms and internalization, with effect sizes ranging from - 0.16 (95% CI - 0.27, - 0.06) to - 0.61 (95% CI - 0.29, - 0.04). Despite several studies that demonstrated positive impacts on BMI, there was no significant effect on BMI-related measures in the meta-analysis. The risk of publication bias was low for the majority of the pooled effect results. 

**Conclusion** 
Preventive interventions were effective for either high BMI or EDs. However, there is limited evidence to show that current preventive interventions were effective in reducing both outcomes. Further research is necessary to explore the risk factors that are shared by these weight-related disorders as well as effective prevention interventions.
AN  - WOS:000847200200001
AU  - Le,
AU  - L.
AU  - K.
AU  - D.
AU  - Tan,
AU  - E.
AU  - J.
AU  - Perez,
AU  - J.
AU  - K.
AU  - Chiotelis,
AU  - O.
AU  - Hay,
AU  - P.
AU  - Ananthapavan,
AU  - J.
AU  - Lee,
AU  - Y.
AU  - Y.
AU  - Mihalopoulos,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40519-022-01458-8_
L1  - internal-pdf://2103297878/Le-Prevention of high body mass index and eati.pdf
PY  - 2022
SP  - 15
T2  - Eating and Weight Disorders-Studies on Anorexia Bulimia and Obesity
TI  - Prevention of high body mass index and eating disorders: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000847200200001
UR  - https://link.springer.com/content/pdf/10.1007/s40519-022-01458-8.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: Although the clinical efficacy and safety of combination of pharmacotherapy and psychotherapy in the treatment of depressive disorders in children and adolescents have been studied, the results remain controversial. This meta-analysis aimed to study the short-term efficacy and acceptability of combined therapy for children and adolescents with depressive disorders. 

METHODS: We conducted a systematic search in multiple databases for randomised controlled trials (RCTs), up to 31 December 2020, that assessed the combination of pharmacotherapy and psychotherapy against other active treatment options (pharmacotherapy, psychotherapy and placebo combined psychotherapy) in children and adolescents ( &lt;= 18 years old) with depressive disorder. This study was registered with PROSPERO (CRD42020196701). 

RESULTS: A total of 14 RCTs involving 1,325 patients were included. For the primary and secondary outcomes, there were no statistically significant differences between the compared interventions in terms of remission (odds ratios [OR] = 1.37; 95% confidence interval [CI]: 0.93 to 2.04), acceptability (OR = 0.99; 95% CI: 0.72 to 1.38), efficacy (standardised mean differences = -0.07; 95% CI: -0.32 to 0.19), and suicidality (OR = 1.17; 95% CI: 0.67 to 2.06). Limited evidence showed that the combination of fluoxetine (OR = 1.90, 95% CI: 1.10 to 3.29) or non-selective serotonin reuptake inhibitors (non-SSRI) (OR = 2.46, 95% CI: 1.06 to 5.72) with cognitive-behavioural therapy (CBT) was superior to other active treatment options. Most included trials were rated as &#039;some concerns&#039; in terms of risk of bias assessment. 

CONCLUSION: There is no evidence from the limited available data that all combined therapies are superior to other active treatment options for the acute treatment of depressive disorder in children and adolescents. However, it showed that fluoxetine or non-SSRI pharmacotherapies combined with CBT might be superior to other therapies in short-term. Mixed characteristics (e.g. age) and small sample size of non-SSRI combined therapy may influence the generalisability of the results.
AN  - 35193522
AU  - Xiang,
AU  - Y.
AU  - Cuijpers,
AU  - P.
AU  - Teng,
AU  - T.
AU  - Li,
AU  - X.
AU  - Fan,
AU  - L.
AU  - Liu,
AU  - X.
AU  - Jiang,
AU  - Y.
AU  - Du,
AU  - K.
AU  - Lin,
AU  - J.
AU  - Zhou,
AU  - X.
AU  - Xie,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12888-022-03760-2
L1  - internal-pdf://3253800662/Comparative short-term efficacy and accep-2022.pdf
PY  - 2022
SP  - 139
T2  - BMC Psychiatry
TI  - Comparative short-term efficacy and acceptability of a combination of pharmacotherapy and psychotherapy for depressive disorder in children and adolescents: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=35193522
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862472/pdf/12888_2022_Article_3760.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - Although treatment guidelines recommend interventions entailing caregiver involvement for children and adolescents following traumatic experiences, evidence on their effectiveness is inconsistent. The present systematic review and meta-analysis considered possible moderators of their effectiveness. METHOD: Eligible studies were (quasi-)randomized controlled trials and efficacy trials published in English or German with participants up to the age of 21 years presenting symptoms of mental disorders due to traumatic experiences. The effectiveness of interventions entailing any kind and extent of caregiver involvement had to be investigated by applying evaluated instruments. PubMed, PsycINFO, ERIC, COCHRANE and PSYNDEX were searched. RESULTS: A total of 33 studies with 36 independent samples were retrieved. Child- and parent-reports on PTSD, depression, anxiety, ADHD, internalizing, externalizing symptoms and behavior problems were analyzed where available. The pooled effect size is significant and robust at post-treatment for child-reported PTSD, g = - 0.34 (95% CI = - 0.53; - 0.14), parent-reported PTSD, g = - 0.41 (95% CI = - 0.71; - 0.11), child-reported depression, g = - 0.29 (95% CI = - 0.46; - 0.11), child-reported anxiety, g = - 0.25 (95% CI = - 0.42; - 0.08), and parent-reported internalizing symptoms, g = - 0.27 (95% CI = - 0.47; - 0.07). Female sex and fulfilling diagnostic criteria appeared as potential moderators. The only significant effect size at follow-up is found for child-reported PTSD symptoms 12 months post-treatment, g = - 0.37 (95% CI = - 0.67; - 0.07). CONCLUSIONS: Interventions entailing caregiver involvement revealed greater symptom reductions than control conditions. Determinants of their effectiveness should be examined further.
AN  - 36161385
AU  - Szota,
AU  - K.
AU  - Schulte,
AU  - K.
AU  - L.
AU  - Christiansen,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-022-00415-2
L1  - internal-pdf://2888492069/Szota-2022-Interventions Involving Caregivers.pdf
PY  - 2022
SP  - 26
T2  - Clinical Child &amp; Family Psychology Review
TI  - Interventions Involving Caregivers for Children and Adolescents Following Traumatic Events: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36161385
UR  - https://link.springer.com/content/pdf/10.1007/s10567-022-00415-2.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - The current systematic review and meta-analyses examined the efficacy of psychological interventions targeting behavioural inhibition and anxiety in preschool-aged children, evaluated within randomised controlled trials. Web of Science, MEDLINE, PsycINFO and CINAHL were systematically searched from inception to March 2021. Ten studies (N = 1475 children, aged 3 - 7 years) were included in the current review. Separate analyses were conducted for behavioural inhibition, anxiety symptoms, and anxiety diagnosis as reported by parents, teachers, and observer-ratings. Pooled outcomes ranged from post-intervention to 12-month follow-up due to the limited number of studies. Meta-analyses revealed that intervention did not reduce behavioural inhibition as assessed by independent observers (SMD = -0.13, 95% CI = -0.63 to.38), but did reduce behavioural inhibition as reported by parents (SMC = -0.64, 95% CI = -1.00 to -0.27) and teachers (SMD = -0.69, 95% CI = -1.02 to -0.36). Additionally, intervention appeared to reduce the risk of anxiety disorders (RR =0.75, 95% CI =0.62 to.90), and parent-report anxiety symptoms (SMC = -0.47, 95% CI = -0.83 to -0.12) in preschool-aged children. Intervention may be efficacious in reducing anxiety in preschool-aged behaviourally inhibited children. It is less clear whether intervention leads to change in BI.
AN  - 35366584
AU  - Ooi,
AU  - J.
AU  - Dodd,
AU  - H.
AU  - F.
AU  - Meiser-Stedman,
AU  - R.
AU  - Hudson,
AU  - J.
AU  - L.
AU  - Bridges,
AU  - J.
AU  - Pass,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.janxdis.2022.102559
L1  - internal-pdf://0948460070/The efficacy of interventions for behavio-2022.pdf
PY  - 2022
SP  - 102559
T2  - Journal of Anxiety Disorders
TI  - The efficacy of interventions for behaviourally inhibited preschool-aged children: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35366584
UR  - https://www.sciencedirect.com/science/article/pii/S0887618522000329?via%3Dihub
VL  - 88
ER  -
TY  - JOUR
AB  - INTRODUCTION: Nocturnal enuresis (NE) is a common pathology in children that can have significant behavioral, emotional, and social impacts on a child&#039;s life. Recent studies have assessed PTENS as a potential treatment method for NE, particularly in those who do not respond to initial first-line treatments. Literature has shown varying results with regard to its success. There has been no systematic review and meta-analysis to date assessing outcomes following this treatment. 

OBJECTIVES: Despite multiple studies showing the potential benefits of PTENS in NE, there has been no consensus regarding its efficacy. The aim of this study was to systematically analyze the effects of PTENS on children with NE. 

STUDY DESIGN: In September 2021, a search of PubMed, Embase and the Cochrane Library was carried out for studies relating to outcomes following PTENS in children with NE. Studies included were original publication English language randomized controlled trial (RCT&#039;s) with at least ten children receiving parasacral transcutaneous electrical nerve stimulation (PTENS). After assessing for relevant studies, data were collated and analyzed from the included studies. Risk of bias was assessed using the Cochrane seven domain assessment. Our primary outcome was response and nonresponse to treatment. These results were combined in a fixed effects meta-analysis model to obtain an overall estimate of the success rate. Information regarding demographics was also collected. There was no external funding for this review. 

RESULTS: Of 145 studies found initially, four RCT&#039;s (208 children) were included. The weighted mean rate of full response to active PTENS was 10.8% (0%-19%). All studies considered, meta-analysis showed no difference between PTENS and controls (RR: 0.70, 95% confidence interval [CI: 0.37-1.32]). Subgroup analysis of monosymptomatic enuresis showed no effect of PTENS compared to controls (RR = 0.58, 95% CI: [0.24-1.42]). When grouped, studies comparing PTENS to sham/behavioral treatment showed no benefit compared to controls (RR = 0.81, 95% CI: [0.05-12.53]) and those comparing PTENS to biofeedback/interferential current (IFC) showed no difference to controls (RR = 0.69, 95% CI: [0.36-1.33]). There was no evidence of a difference between cases and controls between these latter subgroups (RR = 0.70, 95% CI: [0.37-1.32]). 

DISCUSSION/CONCLUSION: Our results suggest that PTENS has no clear benefit in the management of children with NE compared to controls. Subgroup analysis showed that its use in monosymptomatic NE has no clear advantage. However, this review has highlighted the need for further high quality studies. Limitations to this review included a relatively small sample size and the use of prior or concomitant therapies.
AN  - 36069167
AU  - Toale,
AU  - J.
AU  - Kelly,
AU  - G.
AU  - Hajduk,
AU  - P.
AU  - Cascio,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/nau.25039
L1  - internal-pdf://3630756102/Toale-2022-Assessing the outcomes of parasacra.pdf
PY  - 2022
SP  - 07
T2  - Neurourology &amp; Urodynamics
TI  - Assessing the outcomes of parasacral transcutaneous electrical nerve stimulation (PTENS) in the treatment of enuresis in children: A systematic review and meta-analysis of randomized control trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36069167
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/nau.25039?download=true
VL  - 07
ER  -
TY  - JOUR
AB  - Multiple psychosocial interventions to treat ADHD symptoms have been developed and empirically tested. However, no clear recommendations exist regarding the utilization of these interventions for treating core ADHD symptoms across different populations. The objective of this systematic review and meta-analysis by the CADDRA Guidelines work Group was to generate such recommendations, using recent evidence. Randomized controlled trials (RCT) and meta-analyses (MA) from 2010 to 13 February 2020 were searched in PubMed, PsycINFO, EMBASE, EBM Reviews and CINAHL. Studies of populations with significant levels of comorbidities were excluded. Thirty-one studies were included in the qualitative synthesis (22 RCT, 9 MA) and 24 studies (19 RCT, 5 MA) were included in the quantitative synthesis. Using three-level meta-analyses to pool results of multiple observations from each RCT, as well as four-level meta-analyses to pool results from multiples outcomes and multiple studies of each MA, we generated recommendations using the GRADE approach for: Cognitive Behavioral Therapy; Physical Exercise and Mind-Body intervention; Caregiver intervention; School-based and Executive intervention; and other interventions for core ADHD symptoms across Preschooler, Child, Adolescent and Adult populations. The evidence supports a recommendation for Cognitive Behavioral Therapy for adults and Caregiver intervention for Children, but not for preschoolers. There were not enough data to provide recommendations for the other types of psychosocial interventions. Our results are in line with previous meta-analytic assessments; however, they provide a more in-depth assessment of the effect of psychosocial intervention on core ADHD symptoms.
AN  - 36009086
AU  - Tourjman,
AU  - V.
AU  - Louis-Nascan,
AU  - G.
AU  - Ahmed,
AU  - G.
AU  - DuBow,
AU  - A.
AU  - Cote,
AU  - H.
AU  - Daly,
AU  - N.
AU  - Daoud,
AU  - G.
AU  - Espinet,
AU  - S.
AU  - Flood,
AU  - J.
AU  - Gagnier-Marandola,
AU  - E.
AU  - Gignac,
AU  - M.
AU  - Graziosi,
AU  - G.
AU  - Mansuri,
AU  - Z.
AU  - Sadek,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/brainsci12081023
L1  - internal-pdf://2182384977/Tourjman-2022-Psychosocial Interventions for A.pdf
PY  - 2022
SP  - 01
T2  - Brain Sciences
TI  - Psychosocial Interventions for Attention Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis by the CADDRA Guidelines Work GROUP
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36009086
UR  - https://mdpi-res.com/d_attachment/brainsci/brainsci-12-01023/article_deploy/brainsci-12-01023-v2.pdf?version=1660130308
VL  - 12
ER  -
TY  - JOUR
AB  - Lifestyle risk behaviors often co-occur and are prevalent among adolescents. Parent-based interventions addressing risk behaviors concurrently have the potential to improve youth and parent outcomes. This systematic review evaluated the efficacy of parent-based interventions targeting multiple lifestyle risk behaviors among adolescents and parents. MEDLINE (Ovid), Embase (Ovid), PsycInfo (Ovid), Scopus, CINAHL, the Cochrane Database of Systematic Reviews (CDSR) and Cochrane Central Register of Controlled Trials (CENTRAL) were searched from 2010-May 2021. Eligible studies were randomised controlled trials (RCTs) of parent-based interventions addressing 2+ risk behaviors: alcohol use, smoking, poor diet, physical inactivity, sedentary behaviors, and poor sleep. Studies directly targeting parents, and that assessed adolescent outcomes (11-18 years) were eligible. Where possible, random-effects meta-analysis was conducted. From 11,975 identified records, 46 publications of 36 RCTs (n = 28,322 youth, n = 7385 parents) were eligible. Parent-based interventions were associated with improved adolescent moderate-to-vigorous physical activity (MVPA) [Odds Ratio (OR) = 1.82, 95% CI = 1.18, 2.81; p = 0.007], and reduced screen time (SMD = -0.39, 95% CI = -0.62, -0.16, p = 0.0009) and discretionary food intake (SMD = -0.18; 95% CI = -0.30, -0.06; p = 0.002) compared to controls. However, there was some evidence that interventions increased the odds of ever using tobacco in the medium-term (OR = 1.47, 95% CI = 0.99, 2.18, p = 0.06) and of past month tobacco use in the long-term (OR = 1.46, 95% CI = 1.12, 1.90; p = 0.005). Overall, the quality of evidence was moderate. Parent-based interventions targeting multiple risk behaviors improved adolescent MVPA, and reduced screen time discretionary food intake. Further research is needed to address sleep problems and increase intervention efficacy, particularly for alcohol and tobacco use.
AN  - 36075490
AU  - Champion,
AU  - K.
AU  - E.
AU  - Gardner,
AU  - L.
AU  - A.
AU  - McCann,
AU  - K.
AU  - Hunter,
AU  - E.
AU  - Parmenter,
AU  - B.
AU  - Aitken,
AU  - T.
AU  - Chapman,
AU  - C.
AU  - Spring,
AU  - B.
AU  - Thornton,
AU  - L.
AU  - Slade,
AU  - T.
AU  - Teesson,
AU  - M.
AU  - Newton,
AU  - N.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ypmed.2022.107247
L1  - internal-pdf://2514266759/1-s2.0-S0091743522002961-main.cleaned.pdf
PY  - 2022
SP  - 107247
T2  - Preventive Medicine
TI  - Parent-based interventions to improve multiple lifestyle risk behaviors among adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36075490
UR  - https://www.sciencedirect.com/science/article/pii/S0091743522002961?via%3Dihub
VL  - 164
ER  -
TY  - JOUR
AB  - **Background**
Autism spectrum disorders (ASD) is diagnosed primarily by the presence of impaired social interaction, social communication, and stereotypical behaviors. Bumetanide, a loop diuretic which acts by inhibiting Na+-K+-2Cl co-transporters (NKCC): NKCC1 and NKCC2 are explored as a pharmacological agent for treatment of ASD. Aim and 

**Objectives**
The aim of the study was to analyze safety and efficacy of bumetanide in treatment of ASD. 

**Material(s) and Method(s)**
Electronic database search in PUBMED and Cochrane library was conducted using MeSH search terms &quot;Autism&quot; AND &quot;Bumetanide.&quot; Randomized or cross-over trials comparing efficacy of bumetanide versus placebo in ASD patients of any age group were included in analysis. Quantity of reduction in total Childhood Autism Rating Scale (CARS) score after 90 days of treatment with bumetanide was the primary outcome measure analyzed. Efficacy outcome measures were estimated by calculating the Mean Difference (MD) values and their 95% Confidence Intervals (CI) by both fixed and random effect models using Revman 5.4.1 software. 

**Result(s)**
A total of six trials were found to be eligible and included in quantitative synthesis of efficacy. Small but significant decrease in total CARS score (MD: -1.86, 95% CI: -3.20, -0.15, n = 352) and total social responsive scale score (MD: -9.38, 95% CI: -16.45, -2.31, n = 171) on day 91 was evident in bumetanide treated group. Conclusion(s): Bumetanide appears to provide small but significant benefits in relieving ASD symptoms. These benefits are lesser in Chinese patients compared to European patients. Copyright &copy; 2022 Sharanabasayyaswamy Basayya Hiremath and Srinivas Lokikere Devendrappa.
AN  - 2017036933
AU  - Hiremath,
AU  - S.
AU  - B.
AU  - Devendrappa,
AU  - S.
AU  - L.
DB  - Alerts 6_2022.enl
DO  - /10.5455/njppp.2022.12.04189202202052022
L1  - internal-pdf://0338609796/28-1651126193.pdf
PY  - 2022
SP  - 717-722
T2  - National Journal of Physiology, Pharmacy and Pharmacology
TI  - Bumetanide for autism spectrum disorders: A systematic review and meta-analysis
UR  - http://www.njppp.com/fulltext/28-1651126193.pdf?1654079505
VL  - 12(6)
ER  -
TY  - JOUR
AB  - CONTEXT: Previous reviews of mental health interventions have focused on adolescents (10-19 years), with a paucity of comprehensive evidence syntheses on preventive interventions for school-aged children (5-10 years). 

OBJECTIVE: To summarize and synthesize the available evidence from systematic reviews of mental health and positive development interventions for children aged 5-14.9 years in both high-income (HIC) and low- and middle-income countries (LMIC), with a focus on preventive and promotive strategies. 

DATA SOURCES: This overview includes all relevant reviews from OVID Medline, The Cochrane Library, and Campbell Systematic Reviews through December 2020. 

STUDY SELECTION: We included systematic reviews that synthesized empirical studies using experimental or quasi-experimental designs to evaluate the effectiveness of interventions in children aged 5-14.9 years. 

DATA EXTRACTION: Data extraction and quality assessment were completed independently and in duplicate by two review authors. The AMSTAR2 tool was used to assess methodological quality. 

RESULTS: We included 162 reviews. The greatest evidence was found in support of school-based universal and anti-bullying interventions in predominantly HIC. Moderate evidence was found for the use of substance abuse prevention, and early learning and positive development interventions in mixed settings. In LMIC-only contexts, the most promising evidence was found for positive youth development programs. 

LIMITATIONS: The review was primarily limited by paucity of high-quality research due to methodological issues and high heterogeneity. 

CONCLUSIONS: This overview of reviews highlights the need for further research to consolidate findings and understand the specific criteria involved in creating positive mental health and development outcomes from the various interventions considered.
AN  - 35503329
AU  - Harrison,
AU  - L.
AU  - Sharma,
AU  - N.
AU  - Irfan,
AU  - O.
AU  - Zaman,
AU  - M.
AU  - Vaivada,
AU  - T.
AU  - Bhutta,
AU  - Z.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1542/peds.2021-053852G
L1  - internal-pdf://2405508892/Mental Health and Positive Development Pr-2022.pdf
PY  - 2022
SP  - 01
T2  - Pediatrics
TI  - Mental Health and Positive Development Prevention Interventions: Overview of Systematic Reviews
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35503329
UR  - https://publications.aap.org/pediatrics/article/149/Supplement%206/e2021053852G/186940/Mental-Health-and-Positive-Development-Prevention
UR  - https://watermark.silverchair.com/peds_2021053852g.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtIwggLOBgkqhkiG9w0BBwagggK_MIICuwIBADCCArQGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMfmhA7BhoBWT5eTYEAgEQgIIChXf56YNWQ-M1JfPHhclduy_TUCeitEwo9wshP2dGpVY8rIC1JdjjGkxrSOkwNBPpFkpv3SWIukJUERvAix4_HSCS2pgY7aXfobqNDgqaT9UIfybSBG2sNeV3INpZwb-nRQPUj6wOYIDyLZRCfVrwpH3gH2tGSflGNz8wGgNevJW3WX9v4gY8zB_TWeE1M7ZX0g3fCAIlS452-sUNyw2tTd5smahhz2FsX54l9EybtBEUljWVaXrsEPdTOm9B6utnfKuMbsrYP1XajDzsR8XSQtS7dsC96t6Wcy5agQ-EB91EcAcKuvIRKIPtKyX9JFm_HnkOmtNhc0Ro02Up-KWC6GDeXrX8ajgGwLdRN0GV6wAnWQLyfsLOxw7_wbJCHXSVQtrGTnocRDfBcVJSz_CiHphYRQh6Fg_SuBJHIp4yNxz3JNcz5-i-7o27-vUPBPa27SgfGGQXjxYKN4R4G6iD1vg0romvIXEMVIM8dfPDffgn-31cHeJw8fhYw5yUYyZQ0JmB2NsSHkHIme0Bdx0PQKjGYycNLmOCEofmmIaUGnOFEpRAKh0yFhdn7lEzNVrw5q_YlBq9aF9Mfr9dm5ilTmK-IAODLbUH9n8CvqMYx1MOtUPH-7DwXNMRX08yfb55lJkhllEWInCLb5ASLwo8thL53jHophhp_qVLpO0gvA15fmCSaUcrHlZSgcHcCWWPSPh9OznIC87CVxTuA_oOORD-F5ffdkzjyPVeFwU3Bj5x8b-p6QhQJtqLPEthWk_vlHBnpis0at-MrAVtP1pdgdcvpwqdjcFuU7wVjTiooZ5iCZSgRfdwpKcyqr8y8Htx7Hg8ffJ2ht3cNPhxJHxqkMvqO21JRg
VL  - 149
ER  -
TY  - JOUR
AB  - Research has shown that academic anxiety can affect academic performance and emotional well-being. Despite previous research emphasizing the importance of understanding academic anxiety and indicating a strong association between academic performance and academic anxiety, no systematic reviews or meta-analyses have examined the effects of academic interventions on academic and anxiety outcomes. This article reports on a meta-analysis of studies examining academic interventions conducted with elementary students (kindergarten to Grade 6), in which both academic achievement and academic anxiety outcomes were reported. The systematic search yielded 13 studies comprising 1545 participants and revealed statistically significant differences favoring academic treatments over the control for academic achievement outcomes (g = 0.63, k = 11) but no statistically significant benefits for academic anxiety outcomes (g = -0.06, k = 11). The authors caution against drawing strong conclusions due to the heterogeneity in effects and the small number of studies in the extant literature.
AN  - 35618374
AU  - Fishstrom,
AU  - S.
AU  - Wang,
AU  - H.
AU  - H.
AU  - Bhat,
AU  - B.
AU  - H.
AU  - Daniel,
AU  - J.
AU  - Dille,
AU  - J.
AU  - Capin,
AU  - P.
AU  - Vaughn,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jsp.2022.03.011
L1  - internal-pdf://1175592717/A meta-analysis of the effects of academi-2022.pdf
PY  - 2022
SP  - 265-284
T2  - Journal of School Psychology
TI  - A meta-analysis of the effects of academic interventions on academic achievement and academic anxiety outcomes in elementary school children
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=35618374
UR  - https://www.sciencedirect.com/science/article/pii/S0022440522000310?via%3Dihub
VL  - 92
ER  -
TY  - JOUR
AB  - In-Classroom physical activity breaks (IcPAB) are a promising way to promote children&#039;s health behaviors, while contributing to the development of their academic and cognitive ability and health outcomes. Yet the effect of the activity breaks, which are exclusive to classroom settings, are still mixed and unclear. Hence, this review was conducted to identify the characteristics and the effects of IcPAB among primary school children. The review protocol was registered on PROSPERO (CRD42021234192). Following the Cochrane guidelines, PubMed, PsycINFO (ProQuest), MEDLINE (EBSCOhost), Embase/Ovid, SportDISCUS (EBSCOhost), Web of Science, Scopus and Academic Search Premier (EBSCOhost) databases were searched to collect data on randomised control trials without a time restriction. The final database search was conducted on the 8 November 2021. Random effects models were used to calculate the effect sizes. The systematic review identified ten eligible studies, nine of which were also included in the meta-analysis. Few studies used the theoretical frameworks and process evaluations. IcPAB showed mixed effectiveness on academic outcomes: i.e., IcPAB had effects on spelling performance (p &lt; 0.05) and foreign language learning (p &lt; 0.01) but not on mathematics and reading performance. Health behaviors such as moderate-to-vigorous physical activity levels were improved (p &lt; 0.01), but IcPAB did not have an impact on cognition outcomes and health outcomes. Given these mixed results, further research is needed underpinned by strong methodological quality, theoretical underpinnings and reliable process evaluation methods.
AN  - 35954831
AU  - Peiris,
AU  - Dlihk
AU  - Duan,
AU  - Y.
AU  - Vandelanotte,
AU  - C.
AU  - Liang,
AU  - W.
AU  - Yang,
AU  - M.
AU  - Baker,
AU  - J.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph19159479
L1  - internal-pdf://1338738424/Peiris.pdf
PY  - 2022
SP  - 02
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Effects of In-Classroom Physical Activity Breaks on Children&#039;s Academic Performance, Cognition, Health Behaviours and Health Outcomes: A Systematic Review and Meta-Analysis of Randomised Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35954831
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-14-00156/article_deploy/ijerph-14-00156.pdf?version=1486465342
VL  - 19
ER  -
TY  - JOUR
AB  - BACKGROUND AND OBJECTIVES: 
Iron is needed for growth and development of infants globally, but preterm and low birth weight (LBW) infants are at risk for severe iron deficiencies. To assess the effect of enteral iron supplementation on mortality, morbidity, growth, and neurodevelopment outcomes in preterm or LBW infants fed human milk. Secondary objectives were to assess the effect on biomarkers and dose and timing. 

METHODS: 
Data sources include PubMed, Embase and Cochrane Library databases to March 16, 2021. Study Selection includes controlled or quasi experimental study designs. Two reviewers independently extracted data. 

RESULTS: 
Eight trials (eleven reports; 1093 participants, 7 countries) were included. No trials reported mortality. At latest follow-up, there was little effect on infection (very low certainty evidence, 4 studies, 401 participants, relative risk [RR] 0.98, 95% confidence interval [95% CI] 0.56 to 1.73, I2 = 0.00%) and necrotising enterocolitis (3 studies, 375 participants, RR 1.47, 95% CI 0.68 to 3.20, I2 = 0.00%). There was an increase in linear growth (length) (moderate certainty evidence, 3 studies, 384 participants, mean difference 0.69 cm, 95% CI 0.01 to 1.37, I2 = 0%) but little effect on weight, head circumference, or cognitive development. There was an improvement in anemia (moderate certainty evidence, 2 studies, 381 participants, RR 0.25, 95% CI 0.10 to 0.62, I2 = 0.00%) but no effect on serum ferritin. Limitations include heterogeneity in the included studies. 

CONCLUSIONS: 
There are important benefits for human milk-fed preterm and LBW infants from enteral iron supplementation. However, more randomized control trials are required to improve the certainty of evidence.
AN  - 35921671
AU  - Manapurath,
AU  - R.
AU  - M.
AU  - Gadapani
AU  - Pathak,
AU  - B.
AU  - Sinha,
AU  - B.
AU  - Upadhyay,
AU  - R.
AU  - P.
AU  - Choudhary,
AU  - T.
AU  - S.
AU  - Chandola,
AU  - T.
AU  - R.
AU  - Mazumdar,
AU  - S.
AU  - Taneja,
AU  - S.
AU  - Bhandari,
AU  - N.
AU  - Chowdhury,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1542/peds.2022-057092I
L1  - internal-pdf://2551809425/Manapurath-2022-Enteral Iron Supplementation i.pdf
PY  - 2022
SP  - 01
T2  - Pediatrics
TI  - Enteral Iron Supplementation in Preterm or Low Birth Weight Infants: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35921671
UR  - https://watermark.silverchair.com/peds_2022057092i.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAvEwggLtBgkqhkiG9w0BBwagggLeMIIC2gIBADCCAtMGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMQJKWxV2QrfbAkTU-AgEQgIICpG4-lVuJZr1zZGPt-WlY2h8lI54uR_rtw8tSgIoxyQiEEuW18bPMEqMnYn7HriuvBEjSad9wr0aC87-bjg71Rco5SXRMS5hANaDL99XzHoVzvQ-f9eKVAdvOQAbqXdthzK-ScMCWsK9n-WS5LNURA3hK_88ZaNkGfKJTO_mw3SsieotB0Dv1BkbSy6InmVRx5pDr5_a2gjZcpNaOue_iCwC3z03KCzjg5vG0u-azayd4-2JiKemw8kEYizEVmOPwZoLgQYf9RKp7ureSLeVMV0DwylIruJB9zVptjnWh2rNFEpG9bNilEAHaQV48jElxlIgHQxVIB8BiHpm7Tpx48veg678bdRg7hLrhz7Eu7bWdYEX6MucSWHqGfYOk-b0AuGmLL8h7JFwTCmBTmrqw4CWIV40X1LUltgxGniG-9TMMmVZYtrb4p7uW6OJkMG2IAJPAMDhGlj3ef0bWQUjFGHTBZiTy0do7xep0nHpsgcKHWmgiKcquIA9Ajo5f5uKyRYHzOIgzUYPY7S94GELw27DXDGnMw_oAtw7jua0Ssf8tBPPBHBbDnRUvn0mz2rf61hwYkSrET5Lpd1vm8vReY_uDkiI4ajikd16rmTWlZIoNjXkTY1mOUXBqIMMbe_SSBl_rMcvzwmhZJJ4zB5nz9FFwz4KOAIn6inJ63Snp1B2BWaAkatT2CTOOSpN5jeA_OcdcA8-JIeeGe-qPwgw7hYzwPwU0zMj3xl-DmTg2WBhR6igwqux2gBXM6juZNqnQ1F5xkAhGwbTOwXI77ogGQ2UExbV2yYTWGTX8MUW6B4f0f8qqAINMkO3rH2ylNzRJdC5UchOUeZABCKQX5qYzPcoFERH_5CKO6b98SogPoxmllvbniyBTCjDefiuJfgABMXVQkzA
VL  - 150
ER  -
TY  - JOUR
AB  - **Objectives**
Peer relationships play a critical role throughout childhood and adolescence. This meta-analysis systematically reviews the effects of mindfulness-based interventions (MBIs) on peer relationships of children and adolescents.

**Methods**
We identified 21 relevant studies from 12 databases. The overall intervention effect size was estimated with the pooled standardized mean difference using random-effects models. Moderator analyses were performed to explore the variability in intervention effects. Fidelity data were synthesized narratively. Risk of bias and publication bias were also assessed.

**Results**
MBIs showed small positive within-group effects (g = 0.48, 95% CI [0.33, 0.62]) and between-group effects (g = 0.40, 95% CI [0.18, 0.62]) on peer relationships. The effects of MBIs on peer relationships varied significantly by participant age and facilitator background.

**Conclusions**
MBIs show promising effects in improving peer relationships among children and adolescents. However, considering the limited evidence currently available, more studies are needed to validate the efficacy of the interventions.
Meta-analysis Pre-registration PROSPERO #CRD42021232836 (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-99630-001
AU  - Dai,
AU  - X.
AU  - Du,
AU  - N.
AU  - Shi,
AU  - S.
AU  - Lu,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12671-022-01966-9
L1  - internal-pdf://0352563064/Dai-2022-Effects of mindfulness-based interven.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Mindfulness
TI  - Effects of mindfulness-based interventions on peer relationships of children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc19&amp;AN=2022-99630-001
UR  - https://link.springer.com/content/pdf/10.1007/s12671-022-01966-9.pdf
ER  -
TY  - JOUR
AB  - Iodine supplementation during pregnancy in areas with mild-moderate deficiency is still a matter of debate. The present study aimed at systematically reviewing currently available evidences provided by meta-analyses with the aim to further clarify controversial aspects regarding the need of iodine supplementation in pregnancy as well as to provide guidance on clinical decision-making, even in areas with mild-moderate deficiency. Medline, Embase and Cochrane search from 1969 to 2022 were performed. For the purpose of this review, only studies containing meta-analytic data were selected. A total of 7 meta-analyses were retrieved. Four meta-analyses evaluated the relationship between iodine status during pregnancy and neonatal and maternal outcomes suggesting the existence of a U-shaped correlation between iodine status and several maternal and neonatal consequences, especially if iodine status is evaluated at the beginning of pregnancy. Three meta-analyses evaluating the results of intervention trials failed to provide straightforward conclusions on the benefits of iodine supplementation in pregnant women in areas with mild-moderate iodine deficiency. Although evidence coming from meta-analyses suggests a role of iodine status during pregnancy in determining maternal and child outcomes, results of meta-analyses of intervention trials are still controversial. Several factors including, degree of iodine deficiency, and pooling studies conducted in areas with different iodine intake, may account for the lack of benefits reported by meta-analyses of intervention trials. More high-quality, randomized, controlled trials including information on timing, dose and regimen of iodine supplementation are needed to further elucidate this issue.
AN  - WOS:000867594800001
AU  - Croce,
AU  - L.
AU  - Chiovato,
AU  - L.
AU  - Tonacchera,
AU  - M.
AU  - Petrosino,
AU  - E.
AU  - Tanda,
AU  - M.
AU  - L.
AU  - Moleti,
AU  - M.
AU  - Magri,
AU  - F.
AU  - Olivieri,
AU  - A.
AU  - Pearce,
AU  - E.
AU  - N.
AU  - Rotondi,
AU  - M.
DB  - Alerts 6_2022.enl
DO  - 10.1007/s11154-022-09760-7
L1  - internal-pdf://2079769236/Croce-Iodine status and supplementation in pre.pdf
PY  - 2022
SP  - 10
T2  - Reviews in Endocrine &amp; Metabolic Disorders
TI  - Iodine status and supplementation in pregnancy: an overview of the evidence provided by meta-analyses
UR  - &lt;Go to ISI&gt;://WOS:000867594800001
UR  - https://link.springer.com/content/pdf/10.1007/s11154-022-09760-7.pdf
ER  -
TY  - JOUR
AB  - **Background**
Schizophrenia at a young age deserves investigation because of the greater severity and burden of illness on individuals and health care than its adult onset. For this study, we included both childhood-onset schizophrenia and early-onset schizophrenia. We used the common term &quot;childhood and adolescent-onset schizophrenia (CAOS)&quot; for either type. This systematic review provides an overview of the clinical use, efficacy, and safety of clozapine treatment in managing CAOS. 

**Methods**
We conducted a systematic literature search in PubMed, Embase, and PsycINFO databases. We searched for randomized controlled trials (RCTs), open-label studies (OLSs), review articles, meta-analytic and observational studies. Our literature search resulted in 1242 search results. After the title, abstract, and full article review, 18 studies qualified (double-blind RCTs n = 4; OLS n = 4; observational studies n = 7; case reports n = 3). 

**Results**
Clozapine use in CAOS was generally well tolerated and not associated with any fatalities. Clozapine use in the short term (6 weeks) and long term (2-9 years) was superior in efficacy than other antipsychotics in CAOS management. Improvement in overall symptoms was maintained during long-term follow-up over the years in OLSs. Clozapine appeared to have a favorable clinical response and shorter hospital stays. Sedation and hypersalivation were commonly reported (90%), constipation was next in frequency (13%-50%). Neutropenia was seen in 6%-15% of cases and agranulocytosis (&lt;0.1%). Although weight gain was common (up to 64%), followed by metabolic changes (8%-22%), treatment-onset diabetes was less frequent (&lt;6%). Akathisia, tachycardia, and blood pressure changes were less commonly seen. 

**Conclusions**
Limited studies indicate that clozapine is a safe and efficacious option for CAOS management. We need large-scale and well-designed long-term RCTs for the use of clozapine in the management of CAOS.
AN  - 35099269
AU  - Adnan,
AU  - M.
AU  - Motiwala,
AU  - F.
AU  - Trivedi,
AU  - C.
AU  - Sultana,
AU  - T.
AU  - Mansuri,
AU  - Z.
AU  - Jain,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1089/cap.2021.0092
L1  - internal-pdf://1307086931/Clozapine for Management of Childhood and-2022.pdf
PY  - 2022
SP  - 28
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Clozapine for Management of Childhood and Adolescent-Onset Schizophrenia: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35099269
UR  - https://www.liebertpub.com/doi/pdf/10.1089/cap.2021.0092?download=true
VL  - 28
ER  -
TY  - JOUR
AB  - A substantial empirical base supports the use of psychotherapy to alleviate anxiety symptoms and diagnoses in children and adolescents. However, focusing only on symptom or diagnostic reduction provides an incomplete picture of clinically meaningful efficacy given that anxiety disorders in this age group are integrally associated with problems in functioning.

A systematic review and meta-analysis (N studies = 40, N participants = 3094) evaluating the impacts of psychotherapy for anxiety was conducted on the following outcomes: global functioning, social functioning, academic functioning, and school attendance. Randomised controlled trials with a passive control condition, a child and/or adolescent sample (7-17 years) with a primary anxiety diagnosis, and receiving anxiety-focused psychotherapy were eligible for inclusion if they reported suitable outcome data. 

Results from the meta-analysis indicated that from pre- to post-treatment, psychotherapy led to significant improvements in global functioning according to clinician (d = 1.55), parent (d = 0.67), and child (d = 0.31) reports and on social functioning according to parent (d = 0.51), but not child (d = 0.31) reports. The qualitative review provided preliminary support psychotherapy&#039;s efficacy in increasing family functioning and school attendance, but not so much in enhancing academic performance. 

These results indicate that psychotherapy improves daily functioning in anxious children and adolescents. The study also highlighted the limited attention paid to measures of functioning in the empirical literature on treatment of childhood anxiety.Trial Registry: This study is registered with PROSPERO under the identification number CRD42021246565. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-80258-001
AU  - Dickson,
AU  - S.
AU  - J.
AU  - Kuhnert,
AU  - R.-L.
AU  - Lavell,
AU  - C.
AU  - H.
AU  - Rapee,
AU  - R.
AU  - M.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s10567-022-00402-7
L1  - internal-pdf://1042988771/Dickson-2022-Impact of psychotherapy for child.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Clinical Child and Family Psychology Review
TI  - Impact of psychotherapy for children and adolescents with anxiety disorders on global and domain-specific functioning: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-80258-001
UR  - https://link.springer.com/content/pdf/10.1007/s10567-022-00402-7.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Depression is widespread among adolescents and seriously endangers their quality of life and academic performance. Developing strategies for adolescent depression has important public health implications. No systematic review on the effectiveness of physical exercise for adolescents aged 12-18 years with depression or depressive symptoms has previously been conducted. This study aims to systematically evaluate the effect of physical exercise on adolescent depression in the hope of developing optimum physical exercise programs. 

METHODS: 
Nine major databases at home and abroad were searched to retrieve randomized controlled trials (RCTs) on exercise interventions among adolescents with depression or depressive symptoms. The retrieval period started from the founding date of each database to May 1, 2021. The methodological quality of the included articles was evaluated using the modified PEDro scale. A meta-analysis, subgroup analysis, sensitivity analysis, and publication bias tests were then conducted. 

RESULTS: 
Fifteen articles, involving 19 comparisons, with a sample size of 1331, were included. Physical exercise significantly reduced adolescent depression (standardized mean difference [SMD] = - 0.64, 95% CI - 0.89, - 0.39, p &lt; 0.01), with a moderate effect size, in both adolescents with depression (SMD = -0.57, 95% CI - 0.90, - 0.23, p &lt; 0.01) and adolescents with depressive symptoms (SMD = - 0.67, 95% CI - 1.00, - 0.33, p &lt; 0.01). In subgroups of different depression categories (depression or depressive symptoms), aerobic exercise was the main form of exercise for the treatment of adolescents with depression. For adolescents with depression, interventions lasting 6 weeks, 30 min/time, and 4 times/week had optimum results. The effects of aerobic exercise and resistance + aerobic exercise in the subgroup of adolescents with depressive symptoms were significant, while the effect of physical and mental exercise (yoga) was not significant. For adolescents with depressive symptoms, aerobic exercise lasting 8 weeks, 75-120 min/time, and 3 times/week had optimum results. Physical exercise with moderate intensity is a better choice for adolescents with depression and depressive symptoms. 

CONCLUSIONS: 
Physical exercise has a positive effect on the improvement of depression in adolescents. The protocol for this study was registered with INPLASY (202170013). DOI number is 10.37766/inplasy2021.7.0013. Registration Date:2021.7.06.
AN  - 35227300
AU  - Wang,
AU  - X.
AU  - Cai,
AU  - Z.
AU  - D.
AU  - Jiang,
AU  - W.
AU  - T.
AU  - Fang,
AU  - Y.
AU  - Y.
AU  - Sun,
AU  - W.
AU  - X.
AU  - Wang,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s13034-022-00453-2
L1  - internal-pdf://3793547337/Systematic review and meta-analysis of th-2022.pdf
PY  - 2022
SP  - 16
T2  - Child &amp; Adolescent Psychiatry &amp; Mental Health [Electronic Resource]
TI  - Systematic review and meta-analysis of the effects of exercise on depression in adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35227300
UR  - https://capmh.biomedcentral.com/track/pdf/10.1186/s13034-022-00453-2.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - To examine current clinical research on the use of transcranial magnetic stimulation (TMS) in the treatment of pediatric and young adult autism spectrum disorder in intellectually capable persons (IC-ASD). We searched peer-reviewed international literature to identify clinical trials investigating TMS as a treatment for behavioral and cognitive symptoms of IC-ASD. We identified sixteen studies and were able to conduct a meta-analysis on twelve of these studies. Seven were open-label or used neurotypical controls for baseline cognitive data, and nine were controlled trials. In the latter, waitlist control groups were often used over sham TMS. Only one study conducted a randomized, parallel, double-blind, and sham controlled trial. Favorable safety data was reported in low frequency repetitive TMS, high frequency repetitive TMS, and intermittent theta burst studies. Compared to TMS research of other neuropsychiatric conditions, significantly lower total TMS pulses were delivered in treatment and neuronavigation was not regularly utilized. Quantitatively, our multivariate meta-analysis results report improvement in cognitive outcomes (pooled Hedges&#039; g = 0.735, 95% CI = 0.242, 1.228; p = 0.009) and primarily Criterion B symptomology of IC-ASD (pooled Hedges&#039; g = 0.435, 95% CI = 0.359, 0.511; p &lt; 0.001) with low frequency repetitive TMS to the dorsolateral prefrontal cortex. The results of our systematic review and meta-analysis data indicate that TMS may offer a promising and safe treatment option for pediatric and young adult patients with IC-ASD. However, future work should include use of neuronavigation software, theta burst protocols, targeting of various brain regions, and robust study design before clinical recommendations can be made.
AN  - 36161554
AU  - Smith,
AU  - J.
AU  - R.
AU  - DiSalvo,
AU  - M.
AU  - Green,
AU  - A.
AU  - Ceranoglu,
AU  - T.
AU  - A.
AU  - Anteraper,
AU  - S.
AU  - A.
AU  - Croarkin,
AU  - P.
AU  - Joshi,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s11065-022-09564-1
L1  - internal-pdf://3198541619/Smith-2022-Treatment Response of Transcranial.pdf
PY  - 2022
SP  - 26
T2  - Neuropsychology Review
TI  - Treatment Response of Transcranial Magnetic Stimulation in Intellectually Capable Youth and Young Adults with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36161554
UR  - https://link.springer.com/article/10.1007/s11065-022-09564-1
UR  - https://link.springer.com/content/pdf/10.1007/s11065-022-09564-1.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - **Objective:** 
To evaluate the effects of different interventions on Internet addiction (IA), a meta-analysis and network meta-analyses were performed. 

**Methods:** 
We searched PubMed, Cochrane, Embase, Web of Science, PsycINFO, ProQuest, CNKI, WanFang, VIP database, and CBM from their inception to August 2021 to identify randomized controlled trials (RCTs) where the effects of interventions on IA were assessed. The risk of bias was evaluated according to the Revised Cochrane risk-of-bias tool for randomized trials (RoB2). The R studio Software and Stata 14.0 were used to perform traditional meta-analysis and network meta-analyses. 

**Results:** 
A total of 59 RCTs including 3832 participants were incorporated into meta-analysis. The results of the traditional meta-analysis of 24 studies showed that CBT, group counseling, sports intervention, and Internet based intervention could significantly reduce IA levels (SMD = -1.90, 95%CI: -2.26 to -1.55, P &lt; 0.01, I-2 = 85.9%) as compared to no-treatment control groups. Network meta-analyses based on different scales showed that combined interventions had the highest probability of being the best interventions for IA (SUCRA = 91.0 % based on IAT; SUCRA = 89.0 % based on CIAS). 

**Discussion:** 
Most interventions have significant effects on the treatment of IA. Compared with single interventions, combined interventions showed a more pronounced improvement in Internet addiction symptoms.
AN  - WOS:000823032700010
AU  - Zhang,
AU  - X.
AU  - Q.
AU  - Zhang,
AU  - J.
AU  - H.
AU  - Zhang,
AU  - K.
AU  - X.
AU  - Ren,
AU  - J.
AU  - Lu,
AU  - X.
AU  - Y.
AU  - Wang,
AU  - T.
AU  - L.
AU  - Yang,
AU  - H.
AU  - Y.
AU  - Guo,
AU  - H.
AU  - Y.
AU  - Yuan,
AU  - G.
AU  - J.
AU  - Zhu,
AU  - Z.
AU  - H.
AU  - Hao,
AU  - J.
AU  - H.
AU  - Sun,
AU  - Y.
AU  - Su,
AU  - P.
AU  - Y.
AU  - Yang,
AU  - L.
AU  - S.
AU  - Zhang,
AU  - Z.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.jad.2022.06.013
L1  - internal-pdf://0104042434/1-s2.0-S0165032722006735-main.cleaned.pdf
PY  - 2022
SP  - 56-71
T2  - Journal of Affective Disorders
TI  - Effects of different interventions on internet addiction: A meta-analysis of random controlled trials
UR  - &lt;Go to ISI&gt;://WOS:000823032700010
UR  - https://www.sciencedirect.com/science/article/pii/S0165032722006735?via%3Dihub
VL  - 313
ER  -
TY  - JOUR
AB  - **Objective:** 
Assess the effectiveness of physical therapy, including supervised physical exercise for body mass index (BMI) restoration; improving muscle strength and the psychological, behavioural, cognitive symptoms and quality of life in patients with anorexia nervosa (AN). 

**Methods:** 
A Systematic Review (SR) was conducted in the following scientific databases: Medline, PubMed, PEDro, PsychInfo, Cochrane Library plus, Nursing and Allied Health database, Scopus and Web of Science databases, from inception until November 2021. An assessment of the risk of bias and the certainty of evidence across studies was conducted. Articles were eligible if they followed randomized and non-randomized control trial designs with treatments based on physical therapy or exercise or physical activity in AN patients. 

**Results:** 
496 records were screened, and after eligibility assessment, 6 studies from 8 articles were finally analysed. The studies, involving 176 AN patient (85.02% of patients), reported improvements in muscle strength, eating behaviour, eating attitude, mood and quality of life. Three studies included nutritional co-interventions and four studies included psychological therapy. None of the studies reported adverse effects. 

**Conclusions:** 
In two of the RCTs included in this SR, strength training and high intensity resistance improved the muscle strength of patients with AN. In addition, in two RCTs, improvements were observed in patients&#039; attitudes towards their bodies after basic body awareness therapy or after full body massage and instruction to relax. In addition, quality of life improved in two studies, with stretching, isometrics, endurance cardiovascular and muscular exercising.
AN  - WOS:000881315000001
AU  - Minano-Garrido,
AU  - E.
AU  - J.
AU  - Catalan-Matamoros,
AU  - D.
AU  - Gomez-Conesa,
AU  - A.
DB  - Alerts 6_2022.enl
DO  - 10.3390/ijerph192113921
L1  - internal-pdf://2189742581/Minano-Garrido-2022-Physical Therapy Intervent.pdf
PY  - 2022
SP  - 13
T2  - International Journal of Environmental Research and Public Health
TI  - Physical Therapy Interventions in Patients with Anorexia Nervosa: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000881315000001
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-19-13921/article_deploy/ijerph-19-13921.pdf?version=1666793044
VL  - 19
ER  -
TY  - JOUR
AB  - Improving parenting, child attachment, and externalizing behaviors: Meta-analysis of the first 25 randomized controlled trials on the effects of Video-feedback Intervention to promote Positive Parenting and Sensitive Discipline (VIPP-SD). VIPP-SD combines support of parental sensitive responsiveness with coaching parents in sensitive limit setting. 

Here, we present meta-analyses of 25 RCTs conducted with more than 2,000 parents and caregivers. Parents or children had various risks. We examined its effectiveness in promoting parental cognitions and behavior regarding sensitive parenting and limit setting, in promoting secure child-parent attachment, and reducing externalizing child behavior. 

Web of Science, MEDLINE, PubMed, and recent reviews were searched for relevant trials (until May 10, 2021). Multilevel meta-analysis with META, METAFOR, and DMETAR in R took account of the 3-level structure of the datasets (studies, participants, measures). The meta-analyses showed substantial combined effect sizes for parenting behavior (r = .18) and attitudes (r = .16), and for child attachment security (r = .23), but not for child externalizing behavior (r = .07). In the subset of studies examining effects on both parenting and attachment, the association between effect sizes for parenting and for attachment amounted to r = .48. 

We consider the way in which VIPP-SD uses video-feedback an active intervention component. Whether VIPP-SD indeed stimulates secure attachment through enhanced positive parenting remains an outstanding question for further experimental study and individual participant data meta-analysis.
AN  - WOS:000743352400001
AU  - van
AU  - Ijzendoorn,
AU  - M.
AU  - H.
AU  - Schuengel,
AU  - C.
AU  - Wang,
AU  - Q.
AU  - Bakermans-Kranenburg,
AU  - M.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1017/S0954579421001462
L1  - internal-pdf://3120474442/Improving parenting, child attachment, and ext.pdf
PY  - 2022
SP  - 16
T2  - Development and Psychopathology
TI  - Improving parenting, child attachment, and externalizing behaviors: Meta-analysis of the first 25 randomized controlled trials on the effects of Video-feedback Intervention to promote Positive Parenting and Sensitive Discipline
UR  - &lt;Go to ISI&gt;://WOS:000743352400001
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/D6711F49014002C4FFB1A713E2A28743/S0954579421001462a.pdf/div-class-title-improving-parenting-child-attachment-and-externalizing-behaviors-meta-analysis-of-the-first-25-randomized-controlled-trials-on-the-effects-of-video-feedback-intervention-to-promote-positive-parenting-and-sensitive-discipline-div.pdf
ER  -
TY  - JOUR
AB  - Most critically ill neonates require constant monitoring, continuous care, and supervision. However, distance created by admission and prolonged stay in a neonatal intensive care unit (NICU) may contribute to a delay in parent-infant bonding. This review aimed to determine how family-centered care (FCC) in the NICU affects parental bonding with critically ill infants. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were used to perform a systematic search of the literature within the following four electronic databases: Cumulative Index of Nursing and Allied Health Literature (CINAHL), MEDLINE, Cochrane Library, and Web of Science. The search was conducted through July/August 2020. Research quality was evaluated using the Johns Hopkins Nursing Evidence-Based Practice Grading Scale. Out of 816 articles identified through literature search, 16 of the studies met our inclusion criteria. The majority of the studies (n = 14) found FCC interventions resulted in a significant increase in parental bonding. Results showed evidence practicing FCC in the NICU setting supports early parent-infant bonding. Nurses should consider implementing evidence-based FCC strategies into practice, such as allowing parents unrestricted access to their infants. More rigorous research with larger samples is recommended. More studies are also needed focusing on father-infant dyads and mother-father-infant triads.
AN  - WOS:000783573000001
AU  - Kutahyalioglu,
AU  - N.
AU  - S.
AU  - Scafide,
AU  - K.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/13674935221085799
L1  - internal-pdf://4268763252/Effects of family-centered care on bonding_ A.pdf
PY  - 2022
SP  - 17
T2  - Journal of Child Health Care
TI  - Effects of family-centered care on bonding: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000783573000001
UR  - https://journals.sagepub.com/doi/pdf/10.1177/13674935221085799
ER  -
TY  - JOUR
AB  - **Background:** 
The developmental consequences of childhood trauma for young children are extensive and impact a diverse range of areas. Young children require treatments that consider their developmental stage and are inclusive of caregiver involvement. Parent-Child Interaction Therapy (PCIT), with its dyadic focus and developmental sensitivity, is uniquely positioned to offer therapeutic support to young children and their families. 

**Aim:** 
The current study aimed to conduct a systematic review of the current literature on PCIT and trauma and determine treatment outcomes for children and caregivers. Method: A systematic review of five electronic databases was undertaken. Studies that utilized PCIT to treat a population who had experienced trauma were included in the review regardless of study design. 

**Results:** 
PCIT was used to treat a population who had experienced trauma in 40 studies. PCIT was an effective treatment in improving a variety of child and parent outcomes in this population including reduced parenting stress, child behavior problems, child trauma symptoms, parental mental health concerns, negative parenting strategies, and reducing potential risk of recidivism of abuse and neglect. These findings should be taken with caution given attrition rates and potential for bias in the study samples. 

**Discussion:**
Clinicians should consider PCIT as a potential treatment for children who have experienced trauma and their families. Future research should incorporate corroborative sources of information, assessment of caregiver and child trauma symptoms, examination of permanency outcomes, and consider standardization of PCIT modifications for child trauma to determine treatment in this population of children.
AN  - WOS:000919803000007
AU  - Warren,
AU  - J.
AU  - M.
AU  - Halpin,
AU  - S.
AU  - A.
AU  - Hanstock,
AU  - T.
AU  - L.
AU  - Hood,
AU  - C.
AU  - Hunt,
AU  - S.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.chiabu.2022.105942
L1  - internal-pdf://1160172913/warren.pdf
PY  - 2022
SP  - 29
T2  - Child Abuse &amp; Neglect
TI  - Outcomes of Parent-Child Interaction Therapy (PCIT) for families presenting with child maltreatment: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000919803000007
VL  - 134
ER  -
TY  - JOUR
AB  - **Background:** 
Aided augmentative and alternative communication (AAC) interventions have been shown to be effective in teaching children with autism spectrum disorder (ASD) to communicate for a range of communication functions. However, currently little is known about the specific characteristics of interventions that can be used to teach functions other than object request. 

**Method:** 
A systematic search and appraisal was undertaken of extant ASD-AAC research to determine whether outcomes varied according to intervention strategies used, communication functions and behaviours targeted, treatment intensity, and participant characteristics. Eighteen studies were identified and appraised for constituents and outcomes. 

**Results:** 
Intervention components varied widely, as did behaviours targeted, participant characteristics, dosage, and outcomes. There was evidence that a range of functions and communication behaviours could be taught successfully in structured, context-bound routines, with the teaching strategies of time delay and prompting applied most frequently. A small correlation was found between dosage and effect size. 

**Conclusions:** 
The current appraisal provides evidence that children with ASD who use aided AAC can learn communication functions beyond making requests for objects. AAC interventions that include time delay and prompting, and that teach skills in specific routines, are more likely to demonstrate a moderate to large effect size. Further research on the range of factors that may potentially influence outcomes, such as participant characteristics and dosage, is needed. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-18405-001
AU  - Logan,
AU  - K.
AU  - Iacono,
AU  - T.
AU  - Trembath,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.rasd.2021.101896
L1  - internal-pdf://2043624976/A systematic search and appraisal of inte-2022.pdf
PY  - 2022
T2  - Research in Autism Spectrum Disorders Vol 90 2022, ArtID 101896
TI  - A systematic search and appraisal of intervention characteristics used to develop varied communication functions in children with autism who use aided AAC
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-18405-001
UR  - https://www.sciencedirect.com/science/article/pii/S1750946721001719?via%3Dihub
VL  - 90
ER  -
TY  - JOUR
AB  - OBJECTIVES: 
Third wave cognitive behavioural therapies are increasingly used with children and adolescents. This meta-analysis aimed to determine the effectiveness of four third-wave interventions (acceptance and commitment therapy, compassion focused therapy, mindfulness-based cognitive therapy, and metacognitive therapy) for youth. 

METHODS: 
Four electronic databases were used to identify randomized controlled trials, which tested effects related to health, well-being and functioning. Sensitivity analyses considering study quality were conducted and moderators were explored. 

RESULTS: 
The results based on 50 RCTs meeting inclusion criteria indicated emotional symptoms/internalizing problems (g = -.68, 95% CI -.98 to -.37, k = 43, N = 3265), behavioural difficulties/externalizing problems (g = -.62, 95% CI -1.01 to -.22, k = 23, N = 1659), interference from difficulties (g = -.46, 95% CI -.87 to -.05, k = 21, N = 1786), third wave processes (g = .39, 95% CI .17 to .62, k = 22, N = 1900), wellbeing/flourishing (g = .76, 95% CI .35 to 1.17, k = 21, N = 1303) and physical health/pain (g = .72, 95% CI .01 to 1.44, k = 9, N = 1171) yielded significant effects. Effect for quality of life (g = .62, 95% CI -.08 to 1.31, k = 12, N = 1271) was non-significant. When analysing only those studies rated moderate-high quality, third wave interventions yielded significant superiority effects compared to controls for emotional symptoms/internalizing problems (g = -.55, 95% CI -.82 to -.27, k = 28, N = 2110), interference from difficulties (g = -.48, 95% CI -.90 to -.05, k = 21, N = 1605), third wave processes (g = .27, 95% CI .11 to .43, k = 18, N = 1692), well-being/flourishing (g = .50, 95% CI .18 to .81, k = 16, N = 1063), and quality of life (g = .32, 95% CI .04 to .60, k = 10, N = 1212). Behavioural difficulties/externalizing problems (g = -.38, 95% CI -.86 to .10, k = 15, N = 1351) and physical health/pain (g = .52, 95% CI -.14 to 1.17, k = 8, N = 1139) ceased to be significant. Widespread heterogeneity raised concerns about generalizability and follow-up data was relatively sparse. 

CONCLUSIONS: 
This meta-analysis finds promising results for use of third wave CBT with youth, though the review has limitations.
AN  - 36443910
AU  - Perkins,
AU  - A.
AU  - M.
AU  - Meiser-Stedman,
AU  - R.
AU  - Spaul,
AU  - S.
AU  - W.
AU  - Bowers,
AU  - G.
AU  - Perkins,
AU  - A.
AU  - G.
AU  - Pass,
AU  - L.
DB  - Alerts 6_2022.enl
DO  - /10.1111/bjc.12404
L1  - internal-pdf://1726535039/British J Clinic Psychol - 2022 - Perkins_2022.pdf
PY  - 2022
SP  - 28
T2  - British Journal of Clinical Psychology
TI  - The effectiveness of third wave cognitive behavioural therapies for children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36443910
VL  - 28
ER  -
TY  - JOUR
AB  - BACKGROUND: This metaregression analysis examined which behavioral techniques that are commonly used in behavioral parent and teacher training programs for children with attention-deficit/hyperactivity disorder (ADHD) were related to program effectiveness on children&#039;s behavioral outcomes. 

METHODS: We included 32 randomized controlled trials (N = 2594 children) investigating behavioral parent training, teacher training, or a combination, in children with ADHD under 18 years. Outcomes were symptom counts of total ADHD, inattention, and hyperactivity-impulsivity and behavioral problems. The dosage of techniques was extracted from the intervention manuals. Metaregression was used to assess which techniques and intervention characteristics (setting, delivery method, duration, and home-school collaboration) were associated with intervention effectiveness. 

RESULTS: Higher dosage of psycho-education for parents was associated with smaller effects on behavioral problems and, only in case of parent training, also with smaller effects on ADHD symptoms. Higher dosage of teaching parents/teachers to use negative consequences was associated with larger effects on behavioral problems. Individual training compared with group training was associated with larger effects on ADHD and hyperactivity-impulsivity symptoms. 

CONCLUSIONS: This study provides first insights into the specific techniques that are essential in behavioral parent and teacher training programs for children with ADHD. This knowledge can eventually be used to improve and tailor interventions.
AN  - 35417075
AU  - Hornstra,
AU  - R.
AU  - Groenman,
AU  - A.
AU  - P.
AU  - van
AU  - der
AU  - Oord,
AU  - S.
AU  - Luman,
AU  - M.
AU  - Dekkers,
AU  - T.
AU  - J.
AU  - van
AU  - der
AU  - Veen-Mulders,
AU  - L.
AU  - Hoekstra,
AU  - P.
AU  - J.
AU  - van
AU  - den
AU  - Hoofdakker,
AU  - B.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/camh.12561
L1  - internal-pdf://1716736239/Review_ Which components of behavioral pa-2022.pdf
PY  - 2022
SP  - 13
T2  - Child &amp; Adolescent Mental Health
TI  - Review: Which components of behavioral parent and teacher training work for children with ADHD? - a metaregression analysis on child behavioral outcomes
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35417075
VL  - 13
ER  -
TY  - JOUR
AB  - PURPOSE: This systematic review and meta-analysis investigated the effects of parenting education programs (PEPs) for refugee and migrant parents. 

METHODS: A systematic review was conducted according to PRISMA guidelines. Relevant studies published from 2000 to 2020 were identified through a systematic search of six electronic databases (PubMed, Embase, Cochrane Library, CINAHL, RISS, KMBASE). A meta-analysis of the studies was then undertaken. 

RESULTS: Of the 14,996 published works identified, 23 studies satisfied the inclusion criteria, and 19 studies were analyzed to estimate the effect sizes (standardized mean differences) of the PEPs using random-effect models. PEPs were effective for parenting efficacy (effect size [ES]=1.40; 95% confidence interval [CI]: 1.14-1.66), positive parenting behaviors (ES=0.51; 95% CI: 0.30-0.73), parent-child relationships (ES=0.38; 95% CI: 0.22-0.53), and parenting stress (ES=0.64; 95% CI: 0.50-0.79). There were statistically significant differences in the effect sizes of PEPs that included mothers only (ES=0.93), included children under 7 years of age(ES=0.91), did not include child participation (0.77), continued for 19 or more sessions (ES=0.80), and were analyzed in quasi-experimental studies (ES=0.86). The overall effect of publication bias was robust. 

CONCLUSION: PEPs were found to be effective at improving parenting efficacy, positive parenting behaviors, parent-child relationships, and parenting stress.
AN  - 35172078
AU  - Lee,
AU  - I.
AU  - S.
AU  - Kim,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.4094/chnr.2022.28.1.23
L1  - internal-pdf://2620980374/Effects of parenting education programs f-2022.pdf
PY  - 2022
SP  - 23-40
T2  - Child Health Nursing Research
TI  - Effects of parenting education programs for refugee and migrant parents: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35172078
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858783/pdf/chnr-28-1-23.pdf
VL  - 28
ER  -
TY  - JOUR
AB  - The present study aimed to identify which school-based positive psychology interventions are effective for increasing children&#039;s well-being; synthesize existing interventions; and summarize the quality of identified studies. This systematic literature review includes publications up to August 2020, retrieved from the PsycINFO, ERIC and Scopus databases. This review comprises fifteen studies that fit the inclusion and exclusion criteria. Most of the interventions, programs and curricula that aimed to promote children&#039;s well-being focused on elements of subjective well-being, and their effects remained in the short and long-term. Most of the programs that showed a positive effect on well-being were delivered by teachers, which may have enhanced the success of the programs. To be effective, the content of interventions can include a single component or multiple components of well-being. Further research is needed to verify the impact of the effects on well-being through follow-up assessments. The overall quality of the reports is adequate, but most of them lack a randomized controlled design.
AN  - WOS:000766435600001
AU  - de
AU  - Oliveira,
AU  - C.
AU  - Almeida,
AU  - C.
AU  - Giacomoni,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s12187-022-09935-3
L1  - internal-pdf://2255343016/School-Based Positive Psychology Interventions.pdf
PY  - 2022
SP  - 18
T2  - Child Indicators Research
TI  - School-Based Positive Psychology Interventions that Promote Well-Being in Children: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000766435600001
UR  - https://link.springer.com/content/pdf/10.1007/s12187-022-09935-3.pdf
ER  -
TY  - JOUR
AB  - School discipline disproportionality has long been documented in educational research, primarily impacting Black/African American and non-White Hispanic/Latinx students. In response, federal policymakers have encouraged educators to change their disciplinary practice, emphasizing that more proactive support is critical to promoting students&#039; social and behavioral outcomes in school. Results from a literature review conducted nearly a decade ago indicated that there was, at that point, a paucity of empirical research related to considering students&#039; culture (e.g., race, ethnicity) and supporting school behavior. 

The purpose of this study is to replicate and expand the previous review to summarize the characteristics of the most recent school-based quantitative research addressing interventions to promote social and behavioral outcomes for racially and ethnically minoritized youth. We screened 1687 articles for inclusion in the review. 

Upon coding 32 eligible research studies, we found that intervention and implementer characteristics within these studies varied, but noted strong intervention effects in studies that included established evidence-based practices, adapted interventions, as well as new practices piloted with student participants. 

Results inform recommendations to continue to study interventions that promote positive social and behavioral outcomes for racially and ethnically minoritized students to disrupt a long history of subjection to exclusionary discipline disproportionately. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-43479-001
AU  - Fallon,
AU  - L.
AU  - M.
AU  - DeFouw,
AU  - E.
AU  - R.
AU  - Cathcart,
AU  - S.
AU  - C.
AU  - Berkman,
AU  - T.
AU  - S.
AU  - Robinson-Link,
AU  - P.
AU  - O&#039;Keeffe,
AU  - B.
AU  - V.
AU  - Sugai,
AU  - G.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s10864-021-09436-3
L1  - internal-pdf://1895939998/Fallon-2022-School-based supports and interven.pdf
PY  - 2022
SP  - 123-156
T2  - Journal of Behavioral Education
TI  - School-based supports and interventions to improve social and behavioral outcomes with racially and ethnically minoritized youth: A review of recent quantitative research
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-43479-001
UR  - https://link.springer.com/article/10.1007/s10864-021-09436-3
UR  - https://link.springer.com/content/pdf/10.1007/s10864-021-09436-3.pdf
VL  - 31
ER  -
TY  - JOUR
AB  - BACKGROUND: Children and adolescents who experience traumatic events may develop post-traumatic stress disorder (PTSD), which is often associated with other psychiatric disorders, including depression and anxiety. Cognitive behavioral therapy (CBT) is widely used in psychotherapy to treat PTSD in children and adolescents. This meta-analysis evaluated previous studies on the effectiveness of CBT in the treatment of PTSD in children and adolescents. 

METHODS: Randomized controlled trials (RCTs) published before July 25, 2021, were retrieved from seven databases. All RCTs of CBT compared to control, including conventional treatment or other treatments, in children or adolescents with PTSD. Random effect models were employed for all outcomes. Risk of bias was performed by Cochrane Collaboration&#039;s tool. The publication bias was evaluated using the Egger&#039;s regression analysis. 

RESULTS: Nineteen RCTs were included in the meta-analysis. Compared with control, CBT was effective in reducing the symptoms of PTSD in children and adolescents, with a variety of scales used to measure the overall PTSD symptoms: CAPS (SMD = -0.41, 95%CI [-0.71, -0.12]), CPSS (SMD = -0.88, 95%CI [-1.42, -0.34]) and UCLA-PTSD RI (SMD = -1.70, 95%CI [-2.98, -0.42]). Furthermore, CBT also improved the comorbidities of depression (SMD = -0.43, 95%CI [-0.70, -0.17]) and anxiety (SMD = -0.29, 95%CI [-0.56, -0.03]) associated with PTSD. However, CBT was not effective in reducing avoidance symptoms (SMD = 0.38, 95%CI [-0.55, 1.31]). 

CONCLUSION: CBT can reduce the severity of PTSD in children and adolescents and improve the symptoms of depression and anxiety, as evident in the treatment of PTSD victims of sexual abuse and war and in patients aged more than 7 years.
AN  - 35460743
AU  - Xian-Yu,
AU  - C.
AU  - Y.
AU  - Deng,
AU  - N.
AU  - J.
AU  - Zhang,
AU  - J.
AU  - Li,
AU  - H.
AU  - Y.
AU  - Gao,
AU  - T.
AU  - Y.
AU  - Zhang,
AU  - C.
AU  - Gong,
AU  - Q.
AU  - Q.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2022.04.111
L1  - internal-pdf://3457837510/Cognitive behavioral therapy for children-2022.pdf
PY  - 2022
SP  - 502-511
T2  - Journal of Affective Disorders
TI  - Cognitive behavioral therapy for children and adolescents with post-traumatic stress disorder: meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35460743
UR  - https://www.sciencedirect.com/science/article/pii/S0165032722004499?via%3Dihub
VL  - 308
ER  -
TY  - JOUR
AB  - **Background**
Anxiety disorders are among the most common comorbid mental disorders in children and adolescents with attention-deficit hyperactivity disorder (ADHD). While the role of atomoxetine, a non-stimulant medication, is well-established in the management of ADHD symptoms since two decades, there is a dearth of evidence regarding its efficacy in the management of anxiety disorders in children and adolescents with ADHD. 

**Aim(s)**
We aimed to provide insights into (1) the comparative efficacy of atomoxetine in children and adolescents with comorbid ADHD and anxiety disorders, (2) change in severity of anxiety symptoms based on patients&#039;, parents&#039;, and clinicians&#039; ratings, (3) tolerability and side effects. 

**Method(s)**
We searched PubMed, EMBASE, and PsycINFO for clinical trials that addressed the efficacy of atomoxetine for anxiety symptoms in children and adolescents with ADHD. All published literature was systematically reviewed. 

**Result(s)**
We included four studies, out of which two specifically addressed comorbid ADHD and anxiety disorder. The studies suggested that atomoxetine did not exacerbate and in fact reduced anxiety symptoms in young patients with comorbid ADHD. 

**Conclusions and implications**
Overall, atomoxetine demonstrates good efficacy in improving anxiety symptoms in children and adolescents with ADHD. Further studies are needed to shed light on atomoxetine&#039;s efficacy for anxiety subtypes in ADHD. Copyright &copy; 2022 The Authors
AN  - 2018710924
AU  - Khoodoruth,
AU  - M.
AU  - A.
AU  - S.
AU  - Ouanes,
AU  - S.
AU  - Khan,
AU  - Y.
AU  - S.
DB  - Alerts 6_2022.enl
DO  - /10.1016/j.ridd.2022.104275
L1  - internal-pdf://3341732319/1-s2.0-S0891422222001056-main.cleaned.pdf
PY  - 2022
T2  - Research in Developmental Disabilities
TI  - A systematic review of the use of atomoxetine for management of comorbid anxiety disorders in children and adolescents with attention-deficit hyperactivity disorder
UR  - https://www.elsevier.com/locate/redevdis
UR  - https://www.sciencedirect.com/science/article/pii/S0891422222001056?via%3Dihub
VL  - 128 (no pagination)
ER  -
TY  - JOUR
AB  - BACKGROUND: Parent-only interventions for childhood anxiety may be an important alternative to resource and time intensive child-focused cognitive behavioural therapy (CBT). This systematic review and meta-analysis aimed to investigate the efficacy of parent-only interventions in reducing symptoms of anxiety disorders in school-aged children. 

METHODS: A systematic search of five databases (inception to March 2021) identified 29 eligible studies. A range of study designs were captured, including randomised controlled trials (RCTs) and case series. A narrative synthesis was conducted. Random effects meta-analyses were performed on parent- and child-reported outcomes and pre-test post-test effect sizes were calculated for uncontrolled studies. 

RESULTS: Findings indicated a significant treatment effect for parent-only interventions compared to waitlist controls. No significant differences were found when comparing parent-only interventions with other active interventions; anxiety symptoms reduced in both conditions. No significant treatment effects were found for child-rated outcomes. Calculated effect sizes for uncontrolled studies were typically large, although sample sizes were small. No clear evidence was found for a superior type, duration or format of intervention. 

LIMITATIONS: The methodological quality of many studies in this review (19/29) was rated &#039;weak&#039;. Only English language papers were included. 

CONCLUSIONS: To date, this is the first systematic review and meta-analysis of the efficacy of parent-only interventions for reducing symptoms of child anxiety disorders. Our results suggest that parent-only interventions may be effective in reducing child anxiety. These findings are important for clinical practice because they suggest that efficient, low intensity interventions delivered to parents may lead to positive outcomes for children.
AN  - 35460744
AU  - Jewell,
AU  - C.
AU  - Wittkowski,
AU  - A.
AU  - Pratt,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2022.04.082
L1  - internal-pdf://1466061601/The impact of parent-only interventions o-2022.pdf
PY  - 2022
SP  - 20
T2  - Journal of Affective Disorders
TI  - The impact of parent-only interventions on child anxiety: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35460744
UR  - https://www.sciencedirect.com/science/article/pii/S0165032722004207?via%3Dihub
VL  - 20
ER  -
TY  - JOUR
AB  - BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) benefits adults with depression while its efficacy and safety in children and adolescents with major depressive disorder (MDD) remain unclear. We conducted a preliminary meta-analysis here to objectively appraise rTMS in the youth with MDD to inform future research and clinical practice. 

METHODS: We searched Pubmed, Embase, Web of Science and the Cochrane Central Register of Controlled Trials from their inception to December 1, 2021. Studies with a control group or self-controlled designs and evaluating the Hamilton Depression Scale (HAM-D) or the Children&#039;s Depression Rating Scale-Revised (CDRS-R) at baseline and post-rTMS treatment were included. Two reviewers independently selected eligible studies, retrieved data in a structured fashion and assessed studies&#039; quality. Hedges&#039;g with 95% confidence intervals and withdrawal rate with 95% confidential intervals were separately used to evaluate the efficacy and safety of rTMS. 

RESULTS: Thirteen studies with six datasets (165 patients, 61.8% female, age range from 10 to 25years old) were included and our meta-analysis found children and adolescents with MDD benefited from rTMS treatment (Hedges&#039;g 1.37, 95% CI 0.85 to 1.90, P=0.001). In addition, 4% of patients (95% CI 0.02 to 0.09) withdrew during rTMS treatment for reasons including fear, mood swings, suicide ideation and adverse events. 

LIMITATIONS: This conclusion is tempered by a small number of studies included and a potentially existing placebo effect. 

CONCLUSIONS: Our findings suggest rTMS could benefit children and adolescents with MDD in a relatively safe manner, and this result may help guide clinical practice.
AN  - 36174786
AU  - Qiu,
AU  - H.
AU  - Liang,
AU  - K.
AU  - Lu,
AU  - L.
AU  - Gao,
AU  - Y.
AU  - Li,
AU  - H.
AU  - Hu,
AU  - X.
AU  - Xing,
AU  - H.
AU  - Huang,
AU  - X.
AU  - Gong,
AU  - Q.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2022.09.060
L1  - internal-pdf://0470931158/1-s2.0-S0165032722010655-main.cleaned.pdf
PY  - 2022
SP  - 26
T2  - Journal of Affective Disorders
TI  - Efficacy and safety of repetitive transcranial magnetic stimulation in children and adolescents with depression: A systematic review and preliminary meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36174786
UR  - https://www.sciencedirect.com/science/article/pii/S0165032722010655?via%3Dihub
VL  - 26
ER  -
TY  - JOUR
AB  - **Background**
Emerging meta-analytical evidence indicates that baseline exposure to antipsychotics in individuals at clinical high-risk for psychosis (CHR-P) is associated with a higher risk of an imminent transition to psychosis. Despite their tolerability profile and potential beneficial effects, baseline exposure to antidepressants (AD) in CHR-P has surprisingly received far less attention as a potential risk modulator for transition to psychosis. The current systematic review and meta-analysis were performed to fix such a knowledge gap. 

**Methods**
Systematic scrutiny of Medline and Cochrane library, performed up to 1 August 2021, searching for English-language studies on CHR-P reporting numeric data about the sample, the transition outcome at a predefined follow-up time and raw data on AD baseline exposure in relation to such outcome. 

**Results**
Of 1942 identified records, 16 studies were included in the systematic review and meta-analysis. 26% of the participants were already exposed to AD at baseline; at the end of the follow-up 13.5% (95% CI 10.2-17.1%) of them (n = 448) transitioned to psychosis against 21.0% (18.9 to 23.3%) of non-AD exposed CHR-P (n = 1371). CHR-P participants who were already under AD treatment at baseline had a lower risk of transition than non-AD exposed CHR-P. The RR was 0.71 (95% CI 0.56-0.90) in the fixed-effects model (z = -2.79; p = 0.005), and 0.78 (0.58-1.05) in the random-effects model (z = -1.77; p = 0.096; tau-squared = 0.059). There was no relevant heterogeneity (Cochran&#039;s Q = 18.45; df = 15; p = 0.239; I-2 = 18.7%). 

**Conclusions**
 Ongoing AD exposure at inception in CHR-P is associated to a reduced risk of transition to psychosis at follow up.
AN  - WOS:000804997900001
AU  - Raballo,
AU  - A.
AU  - Poletti,
AU  - M.
AU  - Preti,
AU  - A.
DB  - Alerts 6_2022.enl
DO  - 10.1017/s0033291722001428
L1  - internal-pdf://3264728472/Raballo-Do antidepressants prevent transition.pdf
PY  - 2022
SP  - 11
T2  - Psychological Medicine
TI  - Do antidepressants prevent transition to psychosis in individuals at clinical high-risk (CHR-P)? Systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000804997900001
UR  - https://www.cambridge.org/core/journals/psychological-medicine/article/abs/do-antidepressants-prevent-transition-to-psychosis-in-individuals-at-clinical-highrisk-chrp-systematic-review-and-metaanalysis/1BC9491432D2029543D52E7251124C3E
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/1BC9491432D2029543D52E7251124C3E/S0033291722001428a.pdf/div-class-title-do-antidepressants-prevent-transition-to-psychosis-in-individuals-at-clinical-high-risk-chr-p-systematic-review-and-meta-analysis-div.pdf
ER  -
TY  - JOUR
AB  - AIMS: To evaluate the effectiveness of virtual reality (VR) intervention in the management of pain, anxiety and fear in paediatric patients undergoing needle-related procedures. 

DESIGN: A systematic review and meta-analysis of randomized controlled trials (RCTs). 

DATA SOURCES: A librarian-designed search of the Cochrane Library, PubMed, Web of Science, EMBASE, CINAHL, CBM, CNKI, and Wanfang databases was conducted to identify research articles in English or Chinese on RCTs up to February 28, 2022. 

REVIEW METHODS: Two researchers independently screened eligible articles. The Cochrane Handbook for Systematic Reviews was used to assess the risk of bias in the included studies. A fixed- or random-effects meta-analysis model was used to determine the pooled mean difference based on the results of the heterogeneity test. 

RESULTS: A total of 2269 articles were initially screened. The meta-analysis included data from 27 studies representing 2224 participants. Compared with the non-VR group, the VR intervention group significantly reduced pain, anxiety, and fear in paediatric patients who underwent puncture-related procedures. Subgroup analysis showed that VR has advantages over conventional and other distraction methods. 

CONCLUSION: Paediatric patients undergoing needle-related procedures would benefit from VR interventions for pain, anxiety and fear management. 

IMPACT: VR intervention has the potential to reduce pain, anxiety and fear in paediatric patients undergoing puncture-related procedures. Future clinical interventions could incorporate VR into puncture procedures as an effective method to reduce negative emotions in children eligible for VR distractions. 

PATIENT OR PUBLIC CONTRIBUTION: Our paper is a systematic review and meta-analysis and such details don&#039;t apply to our work.
AN  - 36330583
AU  - Gao,
AU  - Y.
AU  - Xu,
AU  - Y.
AU  - Liu,
AU  - N.
AU  - Fan,
AU  - L.
DB  - Alerts 6_2022.enl
DO  - /10.1111/jan.15473
L1  - internal-pdf://3316172193/Guo.pdf
PY  - 2022
SP  - 03
T2  - Journal of Advanced Nursing
TI  - Effectiveness of virtual reality intervention on reducing the pain, anxiety and fear of needle-related procedures in paediatric patients: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36330583
VL  - 03
ER  -
TY  - JOUR
AB  - **Background**
Virtual reality (VR)-based biofeedback is a relatively new intervention and is increasingly being used for the treatment of anxiety disorders. This is the first research synthesis regarding effects and efficacy of this novel mode of treatment. 

**Method**
We conducted a systematic review and meta-analysis of the VR biofeedback literature on treating anxiety symptoms. The MEDLINE/PubMed, Scopus and Web of Science databases were searched for eligible pre-post comparisons and randomized controlled trials (RCTs). We used self-reported anxiety, heart rate (HR), and heart rate variability (HRV) as primary outcome measures. 

**Results**
A total of 7 studies with 191 participants reported VR biofeedback interventions. Of these studies 5 were RCTs, with 103 participants receiving VR biofeedback and 99 control participants (either 2D biofeedback or waiting list controls). We found that VR biofeedback significantly lowers self-reported anxiety (g = -0.28) and HR (g = -0.45), but not HRV. Furthermore, there were no significant differences in outcomes between VR biofeedback and 2D biofeedback but a significant reduction in HR in the VR biofeedback group compared with the waiting list (g = -0.52). 

**Conclusion**
While the first findings are optimistic, more controlled studies with a wider variety of samples are needed to bring this field forward. Particularly, children and adolescents may profit from the combination of gamification elements, VR, and biofeedback.
AN  - WOS:000739738500001
AU  - Kothgassner,
AU  - O.
AU  - D.
AU  - Goreis,
AU  - A.
AU  - Bauda,
AU  - I.
AU  - Ziegenaus,
AU  - A.
AU  - Glenk,
AU  - L.
AU  - M.
AU  - Felnhofer,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00508-021-01991-z
L1  - internal-pdf://3038289548/Virtual reality biofeedback interventions for.pdf
PY  - 2022
SP  - 11
T2  - Wiener Klinische Wochenschrift
TI  - Virtual reality biofeedback interventions for treating anxiety A systematic review, meta-analysis and future perspective
UR  - &lt;Go to ISI&gt;://WOS:000739738500001
UR  - https://link.springer.com/content/pdf/10.1007/s00508-021-01991-z.pdf
ER  -
TY  - JOUR
AB  - Supporting parents through the delivery of evidence-based parenting interventions (EBPI) is a way of promoting children&#039;s rights, given the known benefits to child development and family wellbeing. Group Triple P (GTP) is an EBPI suitable for parents of children aged 2-12 years, who experience parenting difficulties, and/or child behavior problems. Even though GTP has been intensively studied, information lacks on the magnitude of its effects, considering the risk of bias within and across prior research. To address this, a systematic review and meta-analysis (PROSPERO registration CRD42019085360) to evaluate the effects of GTP on child and parent outcomes at short- and longer-term was performed. Through a systematic search of a set of databases, 737 research papers were identified, and 11 trials were selected. The risk of bias within and across studies was evaluated. Significant positive effects of GTP were found immediately after the intervention for child behavior problems, dysfunctional parenting practices, parenting sense of competence, psychological adjustment, parental stress levels, conflict, and relationship quality. Six months after the intervention, positive effects were found only for child behavior problems. Data suggest that GTP might be an effective EBPI leading to positive family outcomes. Substantial risk of bias was found, highlighting the importance of improving the quality of research.
AN  - 35206299
AU  - Nogueira,
AU  - S.
AU  - Canario,
AU  - A.
AU  - C.
AU  - Abreu-Lima,
AU  - I.
AU  - Teixeira,
AU  - P.
AU  - Cruz,
AU  - O.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph19042113
L1  - internal-pdf://0426706178/Nogueira_2022.pdf
PY  - 2022
SP  - 13
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Group Triple P Intervention Effects on Children and Parents: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=35206299
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-14-00156/article_deploy/ijerph-14-00156.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - Internet gaming disorder (IGD) is a formal mental disorder leading to bad outcomes for children and adolescents. This study comprehensively compared the estimated effect of various pharmacotherapy and psychosocial interventions for IGD from randomized controlled trials (RCT) through updated meta-analysis, using meta-regression. A search of PubMed/MEDLINE, Cochrane Library, and Airiti Library between 2000 and 2017 was conducted for various IA/IGD intervention modalities. A total of 124 studies from 29 selected papers involving 5601 children and young adults with IA/IGD were found. Meta-analyzing the pooled standardized mean difference (SMD) revealed a preliminary random effect of 1.399 with a 95% confidence interval of 1.272-1.527, suggesting highly effective treatment of IA/IGD. After adjusting for the confounding risks of age, publication year, type of subjects, and type of study, this study revealed that combining pharmacotherapy with cognitive behavioral therapy (CBT) or multi-level counseling (MLC) was the most effective treatment option. Using a scale of time spent online or a severity of IA symptoms scale was a more effective measurement, with p-values = 0.006 and 0.002, respectively. IA/IGD patients with comorbid depression showed worse outcomes than youth with another comorbidity. The corresponding model goodness-of-fit indices were tau&lt;sup&gt;2&lt;/sup&gt; = 1.188; I&lt;sup&gt;2&lt;/sup&gt;-Residual = 89.74%; and Adjusted-R&lt;sup&gt;2&lt;/sup&gt; = 16.10%. This systematic review indicates that pharmacotherapy combined with CBT or MLC might be an effective therapeutic strategy for youth with gaming disorder.
AN  - 35270305
AU  - Chang,
AU  - C.
AU  - H.
AU  - Chang,
AU  - Y.
AU  - C.
AU  - Yang,
AU  - L.
AU  - Tzang,
AU  - R.
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph19052612
L1  - internal-pdf://3934424716/Chang 2022.cleaned.pdf
PY  - 2022
SP  - 24
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - The Comparative Efficacy of Treatments for Children and Young Adults with Internet Addiction/Internet Gaming Disorder: An Updated Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=35270305
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-14-00156/article_deploy/ijerph-14-00156.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - **Background**
Among people with a diagnosis of borderline personality disorder (BPD) who are engaged in clinical care, prescription rates of psychotropic medications are high, despite the fact that medication use is off‐label as a treatment for BPD. Nevertheless, people with BPD often receive several psychotropic drugs at a time for sustained periods.

**Objectives**
To assess the effects of pharmacological treatment for people with BPD.

**Search methods**
For this update, we searched CENTRAL, MEDLINE, Embase, 14 other databases and four trials registers up to February 2022. We contacted researchers working in the field to ask for additional data from published and unpublished trials, and handsearched relevant journals. We did not restrict the search by year of publication, language or type of publication.

**Selection criteria**
Randomised controlled trials comparing pharmacological treatment to placebo, other pharmacologic treatments or a combination of pharmacologic treatments in people of all ages with a formal diagnosis of BPD. The primary outcomes were BPD symptom severity, self‐harm, suicide‐related outcomes, and psychosocial functioning. Secondary outcomes were individual BPD symptoms, depression, attrition and adverse events.

**Data collection and analysis**
At least two review authors independently selected trials, extracted data, assessed risk of bias using Cochrane&#039;s risk of bias tool and assessed the certainty of the evidence using the GRADE approach. We performed data analysis using Review Manager 5 and quantified the statistical reliability of the data using Trial Sequential Analysis.

**Main results**
We included 46 randomised controlled trials (2769 participants) in this review, 45 of which were eligible for quantitative analysis and comprised 2752 participants with BPD in total. This is 18 more trials than the 2010 review on this topic. Participants were predominantly female except for one trial that included men only. The mean age ranged from 16.2 to 39.7 years across the included trials. Twenty‐nine different types of medications compared to placebo or other medications were included in the analyses. Seventeen trials were funded or partially funded by the pharmaceutical industry, 10 were funded by universities or research foundations, eight received no funding, and 11 had unclear funding.

For all reported effect sizes, negative effect estimates indicate beneficial effects by active medication. Compared with placebo, no difference in effects were observed on any of the primary outcomes at the end of treatment for any medication.

Compared with placebo, medication may have little to no effect on BPD symptom severity, although the evidence is of very low certainty (antipsychotics: SMD ‐0.18, 95% confidence interval (CI) ‐0.45 to 0.08; 8 trials, 951 participants; antidepressants: SMD &minus;0.27, 95% CI &minus;0.65 to 1.18; 2 trials, 87 participants; mood stabilisers: SMD &minus;0.07, 95% CI &minus;0.43 to 0.57; 4 trials, 265 participants).

The evidence is very uncertain about the effect of medication compared with placebo on self‐harm, indicating little to no effect (antipsychotics: RR 0.66, 95% CI 0.15 to 2.84; 2 trials, 76 participants; antidepressants: MD 0.45 points on the Overt Aggression Scale‐Modified‐Self‐Injury item (0‐5 points), 95% CI &minus;10.55 to 11.45; 1 trial, 20 participants; mood stabilisers: RR 1.08, 95% CI 0.79 to 1.48; 1 trial, 276 participants).

The evidence is also very uncertain about the effect of medication compared with placebo on suicide‐related outcomes, with little to no effect (antipsychotics: SMD 0.05, 95 % CI &minus;0.18 to 0.29; 7 trials, 854 participants; antidepressants: SMD &minus;0.26, 95% CI &minus;1.62 to 1.09; 2 trials, 45 participants; mood stabilisers: SMD &minus;0.36, 95% CI &minus;1.96 to 1.25; 2 trials, 44 participants).

Very low‐certainty evidence shows little to no difference between medication and placebo on psychosocial functioning (antipsychotics: SMD &minus;0.16, 95% CI &minus;0.33 to 0.00; 7 trials, 904 participants; antidepressants: SMD &minus;0.25, 95% CI ‐0.57 to 0.06; 4 trials, 161 participants; mood stabilisers: SMD &minus;0.01, 95% CI ‐0.28 to 0.26; 2 trials, 214 participants).

Low‐certainty evidence suggests that antipsychotics may slightly reduce interpersonal problems (SMD &minus;0.21, 95% CI &minus;0.34 to ‐0.08; 8 trials, 907 participants), and that mood stabilisers may result in a reduction in this outcome (SMD &minus;0.58, 95% CI ‐1.14 to ‐0.02; 4 trials, 300 participants). Antidepressants may have little to no effect on interpersonal problems, but the corresponding evidence is very uncertain (SMD &minus;0.07, 95% CI ‐0.69 to 0.55; 2 trials, 119 participants).

The evidence is very uncertain about dropout rates compared with placebo by antipsychotics (RR 1.11, 95% CI 0.89 to 1.38; 13 trials, 1216 participants). Low‐certainty evidence suggests there may be no difference in dropout rates between antidepressants (RR 1.07, 95% CI 0.65 to 1.76; 6 trials, 289 participants) and mood stabilisers (RR 0.89, 95% CI 0.69 to 1.15; 9 trials, 530 participants), compared to placebo.

Reporting on adverse events was poor and mostly non‐standardised. The available evidence on non‐serious adverse events was of very low certainty for antipsychotics (RR 1.07, 95% CI 0.90 to 1.29; 5 trials, 814 participants) and mood stabilisers (RR 0.84, 95% CI 0.70 to 1.01; 1 trial, 276 participants). For antidepressants, no data on adverse events were identified.

**Authors&#039; conclusions**
This review included 18 more trials than the 2010 version, so larger meta‐analyses with more statistical power were feasible. We found mostly very low‐certainty evidence that medication may result in no difference in any primary outcome. The rest of the secondary outcomes were inconclusive. Very limited data were available for serious adverse events. The review supports the continued understanding that no pharmacological therapy seems effective in specifically treating BPD pathology. More research is needed to understand the underlying pathophysiologic mechanisms of BPD better. Also, more trials including comorbidities such as trauma‐related disorders, major depression, substance use disorders, or eating disorders are needed. Additionally, more focus should be put on male and adolescent samples.
AU  - Stoffers-Winterling
AU  - JM,
AU  - Storebø
AU  - OJ,
AU  - Pereira
AU  - Ribeiro
AU  - J,
AU  - Kongerslev
AU  - MT,
AU  - V&ouml;llm
AU  - BA,
AU  - Mattivi
AU  - JT,
AU  - Faltinsen
AU  - E,
AU  - Todorovac
AU  - A,
AU  - Jørgensen
AU  - MS,
AU  - Callesen
AU  - HE,
AU  - Sales
AU  - CP,
AU  - Schaug
AU  - JP,
AU  - Simonsen
AU  - E,
AU  - Lieb
AU  - K.
DB  - Alerts 6_2022.enl
DO  - /10.1002/14651858.CD012956.pub2
L1  - internal-pdf://0785243081/Stoffers-Winterling_et_al-2022-Cochrane_Databa.pdf
PY  - 2022
T2  - Cochrane Database of Systematic Reviews
TI  - Pharmacological interventions for people with borderline personality disorder
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Globally, suicide is the fourth highest cause of adolescent mortality (Suicide: https://www.who.int/news-room/fact-sheets/detail/suicide). The effects of post-primary school-based suicide prevention (PSSP) on adolescent suicidal thoughts and behaviours (STBs) have not been comprehensively synthesised. We aim to estimate the population effect for PSSP interventions on adolescent STBs and explore how intervention effects vary based on intervention and contextual moderators. 

METHODS: 
Searches of PsycINFO, Medline, Education Source, ERIC, Web of Science, and the Cochrane Central Register of Controlled Trials identified cluster randomised trials examining the effectiveness of PSSP on adolescent STBs. The Cochrane Risk of Bias tool assessed bias. Crude and adjusted back-transformed odds ratios (ORs) were calculated. Multilevel random-effects models accounted for dependencies of effects. Univariate meta-regression explored variability of intervention and contextual moderators on pooled effects. 

RESULTS: 
There were 19 and 12 effects for suicidal ideation (SI) and suicide attempts (SA). Compared with controls, interventions were associated with 13% (OR = 0.87, 95%CI [0.78, 0.96]) and 34% (OR = 0.66, 95%CI [0.47, 0.91]) lower crude odds reductions for SI and SA, respectively. Effects were similar for adjusted SI (OR = 0.85, 95%CI [0.75, 0.95]) and SA (OR = 0.72, 95%CI [0.59, 0.87]) models. Within-study (0.20-9.10%) and between-study (0-51.20%) heterogeneity ranged for crude and adjusted SA models and SI heterogeneity was 0%. Moderator analyses did not vary SA effects (ps &gt; .05). 

CONCLUSIONS: 
This meta-analysis contributes to the PSSP evidence-base by demonstrating that PSSP targeting STBs as both primary intervention outcomes and with other health and well-being outcomes reduced SI and SA among 33,155 adolescents attending 329 schools, compared to controls. The number needed to treat estimates suggests the potential of reducing the incidence of SA and SI in one adolescent by implementing PSSP in 1-2 classrooms, supporting PSSP as a clinically relevant suicide prevention strategy. Although moderator analyses were nonsignificant and contained a small number of trials, larger SA effect sizes support particular effectiveness for interventions of a duration of &lt;=1 week, involving multiple stakeholders and with a 12-month follow-up.
AN  - 35289410
AU  - Walsh,
AU  - E.
AU  - H.
AU  - McMahon,
AU  - J.
AU  - Herring,
AU  - M.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13598
L1  - internal-pdf://2391988707/Research Review_ The effect of school-bas-2022.pdf
PY  - 2022
SP  - 15
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Research Review: The effect of school-based suicide prevention on suicidal ideation and suicide attempts and the role of intervention and contextual factors among adolescents: a meta-analysis and meta-regression
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35289410
VL  - 15
ER  -
TY  - JOUR
AB  - **Background**: Suicidal thoughts and behaviors (STBs) among adolescents have hardly decreased despite preventative efforts. School-based prevention programs could have a great reach, yet suicide prevention is not an easy topic to address. To increase acceptability of school-based suicide prevention, it is important to evaluate whether programs that target known risk factors of STBs, such as depression, could be equally effective. 

**Method(s)**: We conducted a systematic literature search in major electronic databases. Outcomes were suicidal ideation and behaviors. Multivariate random effects meta-regression-analyses were conducted. 

**Result(s)**: Eleven primary studies met the inclusion criteria, totalling 23,230 participants. The post-test effect size was small for both suicidal ideation (g = 0.15) and suicidal behaviors (g = 0.30). Meta-regression indicated that targeting known risk factors of STBs was not a significant modifier of effect size for ideation, indicating equal effectiveness. However, it was significant modifier of effect for behaviors, but only one intervention targeted know risk factors. Effects at follow-up (3-12 months) were also significant but small for both outcomes. 

**Limitation(s)**: Substantial heterogeneity between studies was noted. Only few and small sample size studies could be included that targeted known risk factors of STBs. Therefore, these results should be interpreted with caution. 

**Conclusion(s)**: School-based prevention of STBs shows some promise within three months post-test assessments, and potentially also have effects that are sustained over time. More studies are needed to make conclusions regarding school-based interventions that target risk factors of STBs. Copyright &copy; 2021
AN  - 2015609508
AU  - Gijzen,
AU  - M.
AU  - W.
AU  - M.
AU  - Rasing,
AU  - S.
AU  - P.
AU  - A.
AU  - Creemers,
AU  - D.
AU  - H.
AU  - M.
AU  - Engels,
AU  - R.
AU  - C.
AU  - M.
AU  - E.
AU  - Smit,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2021.10.062
L1  - internal-pdf://2230366365/Gijzen-2022.pdf
PY  - 2022
SP  - 408-420
T2  - Journal of Affective Disorders
TI  - Effectiveness of school-based preventive programs in suicidal thoughts and behaviors: A meta-analysis
UR  - http://www.elsevier.com/locate/jad
VL  - Part A. 298
ER  -
TY  - JOUR
AB  - BACKGROUND: Despite the widespread use of psychotropic medications in people with autism spectrum disorder (ASD), there is limited evidence to suggest that psychotropic medications including mood stabilisers are effective in individuals with ASD. AIMS: To carry out a systematic review and meta-analysis of randomised controlled trials (RCTs) that assessed the effectiveness of mood stabilisers in people with ASD. 

METHOD: We searched the following databases: Cochrane Library, MEDLINE, Embase, CINAHL, PsycINFO, ERIC, DARE, and ClinicalTrials.gov. In addition, we hand-searched 12 relevant journals. We used the Cochrane Risk of Bias and Jadad scores to assess the quality of included RCTs. We carried out a meta-analysis using a random-effects model. 

RESULTS: We included eight RCTs (four on valproate, two on levetiracetam, and one each on lamotrigine and topiramate) that included a total of 310 people with ASD, primarily children. Outcomes were based on core and associated ASD symptoms including irritability and aggression but not bipolar disorder. Only two small studies (25%) from the same group showed definite superiority over placebo and one over psychoeducation alone. Meta-analysis of pooled data on the Aberrant Behaviour Checklist-irritability, Clinical Global Impression Scale-improvement, and Overt Aggression Scale (OAS)/OAS-modified did not show any significant inter-group difference. The rates of adverse effects did not show any significant inter-group difference. 

CONCLUSIONS: Given the methodological flaws in the included studies and the contradictory findings, it is difficult to draw any definitive conclusion about the effectiveness of mood stabilisers to treat either ASD core symptoms or associated behaviours. Robust large-scale RCTs are needed in the future to address this issue.PROSPERO registration: CRD42021255467 on 18 May 2021.
AN  - 35197135
AU  - Limbu,
AU  - B.
AU  - Deb,
AU  - S.
AU  - Roy,
AU  - M.
AU  - Lee,
AU  - R.
AU  - Roy,
AU  - A.
AU  - Taiwo,
AU  - O.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/bjo.2022.18
L1  - internal-pdf://0773455638/Randomised controlled trials of mood stab-2022.pdf
PY  - 2022
SP  - e52
T2  - BJPsych Open
TI  - Randomised controlled trials of mood stabilisers for people with autism spectrum disorder: systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35197135
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/9F14E285BB001AFE0B0BD48B05D02FD1/S2056472422000187a.pdf/div-class-title-randomised-controlled-trials-of-mood-stabilisers-for-people-with-autism-spectrum-disorder-systematic-review-and-meta-analysis-div.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - Children of mothers with serious mental health difficulties are at increased risk of developing mental health difficulties themselves in their own lifetime. Specialist interventions delivered in perinatal mental health services offer an opportunity to support the infant&#039;s development and long-term mental health. This review aimed to systematically evaluate the shared elements of successful perinatal mental health interventions that underpin improved outcomes for infants whose mothers experience perinatal mental health difficulties. Nine electronic databases were searched comprehensively for relevant controlled studies of perinatal mental health interventions, and a narrative synthesis undertaken to assess whether statistically significant benefits were noted. Sixteen studies, trialing 19 interventions, were analyzed using a narrative approach and grouped according to reported effectiveness. Eight interventions demonstrated significant improvements in infant outcomes and/or mother-infant relationship outcomes and were used to inform the analysis of the included interventions&#039; components. While the interventions identified were diverse, there were common components which potentially underpin successful interventions for infants whose mothers are experiencing mental health difficulties, including: facilitation of positive MotherxInfant interactions; helping mothers to understand their infant&#039;s perspective or inner world; and the use of video feedback.
AN  - WOS:000760242500005
AU  - Newton,
AU  - K.
AU  - Buck,
AU  - E.
AU  - T.
AU  - Weich,
AU  - S.
AU  - Uttley,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1017/s0954579420001340
L1  - internal-pdf://3274400509/A review and analysis of the components o-2022.pdf
PY  - 2022
SP  - 37-54
T2  - Development and Psychopathology
TI  - A review and analysis of the components of potentially effective perinatal mental health interventions for infant development and mother-infant relationship outcomes
UR  - &lt;Go to ISI&gt;://WOS:000760242500005
UR  - https://www.cambridge.org/core/journals/development-and-psychopathology/article/abs/review-and-analysis-of-the-components-of-potentially-effective-perinatal-mental-health-interventions-for-infant-development-and-motherinfant-relationship-outcomes/73FC3D26B833FE33BAE80A35D0A0BF9F
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/73FC3D26B833FE33BAE80A35D0A0BF9F/S0954579420001340a.pdf/div-class-title-a-review-and-analysis-of-the-components-of-potentially-effective-perinatal-mental-health-interventions-for-infant-development-and-mother-infant-relationship-outcomes-div.pdf
VL  - 34
ER  -
TY  - JOUR
AB  - Problem solving is a common focus of psychological interventions for young people. However, existing evidence syntheses are relatively limited in their scope and conclusions. 

Taking a transdiagnostic approach and incorporating diverse sources of evidence, we examined the role of problem solving as an active ingredient for the indicated prevention and treatment of depression and anxiety in 14-24-year-olds. Three information sources were integrated using framework synthesis: (1) a systematic review of randomized controlled trials of problem solving; (2) a metasynthesis of qualitative evidence on the therapeutic experience of problem solving; and (3) consultations with a Youth Advisory Group. 

Intervention protocols that included problem solving and no more than one other specific component appeared to be effective for depression but not anxiety. Larger multicomponent interventions with a problem-solving element achieved moderate effect sizes for both conditions. There was no clear evidence that effectiveness varied by population characteristics, intervention formats, or contextual factors. Qualitative evidence and youth consultations highlighted positive views about the practicality, simplicity, and flexibility of problem solving. Converging sources also suggested changes in problem orientation as a key transdiagnostic process contributing to positive outcomes. 

Problem solving is a widely applicable therapeutic approach that can help young people with emotional problems to resolve specific stressors and lead to a more hopeful mindset about managing future challenges. Implications for practice are discussed. Copyright &copy; 2022 Society for Adolescent Health and Medicine
AN  - 2019140063
AU  - Michelson,
AU  - D.
AU  - Hodgson,
AU  - E.
AU  - Bernstein,
AU  - A.
AU  - Chorpita,
AU  - B.
AU  - F.
AU  - Patel,
AU  - V.
DB  - Alerts 6_2022.enl
DO  - /10.1016/j.jadohealth.2022.05.005
L1  - internal-pdf://0445172722/1-s2.0-S1054139X22004530-main.cleaned.pdf
PY  - 2022
T2  - Journal of Adolescent Health.
TI  - Problem Solving as an Active Ingredient in Indicated Prevention and Treatment of Youth Depression and Anxiety: An Integrative Review
UR  - https://www.elsevier.com/locate/jadohea
UR  - https://www.sciencedirect.com/science/article/pii/S1054139X22004530?via%3Dihub
ER  -
TY  - JOUR
AB  - OBJECTIVE/BACKGROUND: 
Healthy sleep is particularly important for children with attention deficit hyperactivity disorder (ADHD), as sleep disturbances might aggravate disease symptoms. This review aims to synthesize and report evidence on the effectiveness of sleep interventions in increasing sleep, quality of life (QoL), and ADHD symptoms among children with ADHD. 

PATIENTS/METHODS: 
The systematic literature review follows the Cochrane Collaboration methodology recommendations for literature reviews. Four databases were used based on the population, intervention, control and outcome (PICO) framework. Controlled trials with minimum 20 children in each group, aged 6-18, and published from 2005 and onwards were included. Results from the studies were reported in forest plots and three of the seven review outcomes were synthesized in meta-analyses. 

RESULTS: 
The search identified 7710 records; of which 4808 abstracts were screened. After fulltext-screening of 99 papers, eight papers from five studies were included. The studies included behavioral sleep interventions and pharmacological interventions using melatonin and eszopiclone. For six of the seven outcomes, the effect sizes were small to moderate and the certainty of the evidence was low. For one outcome, sleep disturbances, the effect size was a moderate -0.49 standardized mean differences (95% confidence interval -0.65;-0.33), with a moderate certainty of evidence for the behavioral interventions for children aged 5-13 years with ADHD. 

CONCLUSIONS: 
This review identified few and heterogeneous studies. A moderate certainty of evidence for a moderate effect size was only obtained for sleep disturbances from the behavioral interventions. A low certainty of the evidence for a moderate effect size was found for the total sleep time from the pharmacological intervention using melatonin and one behavioral intervention, which indicates that these sleep interventions impact sleep quantity and quality among children with ADHD.
AN  - 36603513
AU  - Larsson,
AU  - I.
AU  - Aili,
AU  - K.
AU  - Lonn,
AU  - M.
AU  - Svedberg,
AU  - P.
AU  - Nygren,
AU  - J.
AU  - M.
AU  - Ivarsson,
AU  - A.
AU  - Johansson,
AU  - P.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.sleep.2022.12.021
L1  - internal-pdf://0719630702/1-s2.0-S1389945722012709-main.cleaned.pdf
PY  - 2022
SP  - 64-75
T2  - Sleep Medicine
TI  - Sleep interventions for children with attention deficit hyperactivity disorder (ADHD): A systematic literature review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36603513
VL  - 102
ER  -
TY  - JOUR
AB  - We aimed at mapping the meta-analytic evidence base on the efficacy of psychological treatments for posttraumatic stress disorder (PTSD) in specific populations. 

We conducted a systematic search until January 2022 in MEDLINE, PsycINFO, PTSDpubs, Web of Science, and the Cochrane Database of Systematic Reviews for meta-analyses of randomized controlled trials. We contrasted all eligible meta-analyses irrespective of overlapping datasets to present a comprehensive overview of the state of research. Reporting quality was assessed using the AMSTAR 2 tool and certainty of evidence was assessed using established umbrella review criteria. 

Nine meta-analyses with distinct adult populations (51 unique trials) and four with children and adolescents (24 unique trials) were included. Reporting quality of meta-analyses was heterogeneous with risk of bias assessment being rated lowest. The certainty of evidence on the efficacy of psychological interventions for adult populations was thoroughly weak because of small samples and large heterogeneity. In war- and conflict-affected youth, the certainty of evidence was suggestive. 

Our review highlights the need to improve quality of meta-analyses on treatment efficacy for PTSD. More importantly, however, the findings demonstrate the need for new large-scale trials on the efficacy of treatments for PTSD in distinct populations in order to increase certainty of evidence and to identify potential differences in treatment responses.
AD  - Kip, Ahlke. Institute of Psychology, University of Munster, Munster, Germany.Iseke, Linnea N. Institute of Psychology, University of Munster, Munster, Germany.Papola, Davide. WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Science, Section of Psychiatry, University of Verona, Verona, Italy.Gastaldon, Chiara. WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Science, Section of Psychiatry, University of Verona, Verona, Italy.Barbui, Corrado. WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Science, Section of Psychiatry, University of Verona, Verona, Italy.Morina, Nexhmedin. Institute of Psychology, University of Munster, Munster, Germany. Electronic address: morina@uni-muenster.de.
AN  - 36529109
AU  - Kip,
AU  - A.
AU  - Iseke,
AU  - L.
AU  - N.
AU  - Papola,
AU  - D.
AU  - Gastaldon,
AU  - C.
AU  - Barbui,
AU  - C.
AU  - Morina,
AU  - N.
DA  - Dec 13
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.cpr.2022.102239
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://0961434493/1-s2.0-S0272735822001246-main.cleaned.pdf
LA  - English
M3  - Review
N1  - Kip, AhlkeIseke, Linnea NPapola, DavideGastaldon, ChiaraBarbui, CorradoMorina, NexhmedinS0272-7358(22)00124-6
PY  - 2022
SP  - 102239
T2  - Clinical Psychology Review
TI  - Efficacy of psychological interventions for PTSD in distinct populations - An evidence map of meta-analyses using the umbrella review methodology
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36529109
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36529109&amp;id=doi:10.1016%2Fj.cpr.2022.102239&amp;issn=0272-7358&amp;isbn=&amp;volume=100&amp;issue=&amp;spage=102239&amp;pages=102239&amp;date=2022&amp;title=Clinical+Psychology+Review&amp;atitle=Efficacy+of+psychological+interventions+for+PTSD+in+distinct+populations+-+An+evidence+map+of+meta-analyses+using+the+umbrella+review+methodology.&amp;aulast=Kip&amp;pid=%3Cauthor%3EKip+A%3C%2Fauthor%3E%3CAN%3E36529109%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 100
ER  -
TY  - JOUR
AB  - BACKGROUND: 
There are few available antidepressants for pediatric Major Depressive Disorder (MDD). The objective of this systematic review and meta-analysis was to review industry-funded studies of antidepressants in children and adolescents with MDD, and to better understand the contribution of study design and placebo response to the findings of these studies. 

METHODS: 
Randomized, double-blind, placebo-controlled clinical trials that compared antidepressant with placebo for the acute treatment of MDD in children and/or adolescents were selected. Estimates of the standardized mean difference (SMD) in change in Children&#039;s Depression Rating Scale-Revised scores were pooled, after examining for heterogeneity. A random-effects meta-analysis was completed. 

RESULTS: 
Thirty-four antidepressant-placebo comparisons, involving 6161 subjects, were included. The SMD among all studies was 0.12 (CI 0.08, 0.17; p &lt; 0.001), a very small effect size, lower than that seen in studies of adults with MDD. When the meta-analysis was limited to studies with a low mean placebo response, the SMD increased to 0.19 and further increased to 0.22 when studies with at least a 50% chance of receiving placebo were included. LIMITATIONS: Many studies focused on older children and younger adolescents. Our findings may not reflect antidepressant efficacy in older adolescents. 

CONCLUSIONS: 
The modest SMD identified in this analysis may reflect study design factors and the application of antidepressants developed for adults to pediatric patients. Given the urgent clinical need for more pediatric MDD treatments, the influence of placebo response and the need for drug development tailored to this population should be considered in pediatric MDD trial design.
AN  - 35247482
AU  - Feeney,
AU  - A.
AU  - Hock,
AU  - R.
AU  - S.
AU  - Fava,
AU  - M.
AU  - Hernandez
AU  - Ortiz,
AU  - J.
AU  - M.
AU  - Iovieno,
AU  - N.
AU  - Papakostas,
AU  - G.
AU  - I.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2022.02.074
L1  - internal-pdf://4086580725/Antidepressants in children and adolescen-2022.pdf
PY  - 2022
SP  - 55-64
T2  - Journal of Affective Disorders
TI  - Antidepressants in children and adolescents with major depressive disorder and the influence of placebo response: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=35247482
UR  - https://www.sciencedirect.com/science/article/pii/S0165032722002233?via%3Dihub
VL  - 305
ER  -
TY  - JOUR
AB  - Children of anxious parents are at heightened risk of developing an anxiety disorder of their own, but promising research indicates that targeting parenting behaviours can reduce the risk of intergenerational transmission of anxiety. Given there is extensive evidence for the efficacy of treatments for adult anxiety, the current review sought to identify whether interventions solely addressing parental symptoms had any effect on the mental health and wellbeing of their children. Randomised Controlled Trials of psychological interventions targeting adults with a probable anxiety disorder and which included a child mental health or wellbeing outcome were eligible for inclusion. Scopus, Web of Science, PubMed, PsychINFO, and PsychArticles were searched, and 2137 articles were systematically reviewed. However, no articles were identified that met the review criteria. Research into interventions targeting adult anxiety is failing to consider the potential benefit treatment may have on dependent children. This is a missed opportunity to evaluate a potential means of support for children who are known to be at risk of anxiety. Evaluation of psychological interventions for adult anxiety should consider including both adult and child mental health outcomes to determine potential preventative effects.
AN  - 35397376
AU  - Chapman,
AU  - L.
AU  - Hutson,
AU  - R.
AU  - Dunn,
AU  - A.
AU  - Brown,
AU  - M.
AU  - Savill,
AU  - E.
AU  - Cartwright-Hatton,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.janxdis.2022.102557
L1  - internal-pdf://3678161620/The impact of treating parental anxiety o-2022.pdf
PY  - 2022
SP  - 102557
T2  - Journal of Anxiety Disorders
TI  - The impact of treating parental anxiety on children&#039;s mental health: An empty systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35397376
UR  - https://www.sciencedirect.com/science/article/pii/S0887618522000305?via%3Dihub
VL  - 88
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Digital, self-guided cognitive behavioral therapy (CBT) interventions circumvent many barriers to in-person therapy for young people (aged 12-24 years), although adherence to these interventions is low. The absence or insufficient disclosure of recommendations or instructions for appropriate use may account for this. As such, many young people may not self-administer these interventions appropriately or receive the optimal degree of treatment. 

OBJECTIVE: 
This systematic review aims to synthesize the literature on digital CBT for depression and anxiety in young people to describe how appropriate use has been defined and communicated to users as instructions for use, to describe how adherence has been measured, and to determine the associations between adherence and treatment outcomes. 

METHODS: 
A systematic review was conducted with 2 reviewers (SHL and MRA) extracting data independently. Overall, 4 electronic databases (Embase, MEDLINE, PsycINFO, and Cochrane Library) were searched in April 2021 for studies that met the following inclusion criteria: participants aged between 12 and 24 years, evaluated a digital CBT intervention targeting depression or anxiety, and reported instructions or recommendations for use or measures of adherence. Studies that evaluated non-CBT interventions or cognitive- or behavioral-only interventions were excluded. Methodological quality was assessed using the Cochrane Risk of Bias Tool and the Integrated Quality Criteria for the Review of Multiple Study Designs. 

RESULTS: 
There were 32 manuscripts that met the inclusion criteria, of which 28 (88%) were unique studies (N=16,578 youths). Definitions of appropriate use varied among the different interventions in terms of intended recipients, duration and frequency of use, and the features used to support engagement and adherence to appropriate use definitions. Reporting of appropriate use definitions in studies was inconsistent, with no study systematically describing components of appropriate use or providing information on how recommendations for use were relayed to users. Most often, definitions of appropriate use were derived from the study protocol and descriptions of intervention features. Adherence was mostly operationalized as the degree of intervention completion; however, reporting of adherence data was heterogeneous. There was little evidence of an association between degree of use and outcomes in the 9 studies that examined this. 

CONCLUSIONS: 
Definitions of appropriate use are unique to each digital CBT intervention. However, statements of appropriate use are not systematically reported in the literature. Furthermore, the extent to which recommendations for use are communicated to users is not routinely reported. Despite unique definitions of appropriate use, adherence was most often generically operationalized as the degree of intervention completion and was not consistently associated with outcomes. We proposed a framework to promote systematic reporting of definitions of appropriate use for digital interventions to provide guidance to users and to assist the development of appropriate and nuanced measures of adherence. 

TRIAL REGISTRATION: PROSPERO CRD42020208668; https://tinyurl.com/4bu2yram.
AN  - 35976180
AU  - Li,
AU  - S.
AU  - H.
AU  - Achilles,
AU  - M.
AU  - R.
AU  - Werner-Seidler,
AU  - A.
AU  - Beames,
AU  - J.
AU  - R.
AU  - Subotic-Kerry,
AU  - M.
AU  - O&#039;Dea,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/37640
L1  - internal-pdf://0850494037/PDF.cleaned (17).pdf
PY  - 2022
SP  - e37640
T2  - JMIR Mental Health
TI  - Appropriate Use and Operationalization of Adherence to Digital Cognitive Behavioral Therapy for Depression and Anxiety in Youth: Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35976180
VL  - 9
ER  -
TY  - JOUR
AB  - In order to meet the growing need for mental health provision for young people, more attention has turned to schools to provide evidence-based interventions. Acceptance and Commitment Therapy (ACT) has been demonstrated in recent reviews and meta-analyses to be effective with young people, however to date no sys-tematic reviews have examined the use of ACT as a school-based intervention.This systematic review aimed to evaluate the methodological quality and examine the effectiveness of all peer-reviewed literature on ACT interventions based in secondary schools.The PsycInfo, Scopus and Web of Science databases were searched for studies published in any year reporting on the use of ACT interventions based in secondary schools aiming to prevent or reduce mental health difficulties or promote wellbeing. Both universal and targeted studies were eligible for inclusion. Nine studies met inclusion criteria, with a total of 1324 participants across studies (age range 13-21 years).Outcomes measured across all studies were depression, anxiety, anger, psychological capital, stress, wellbeing, life satisfaction, psychological health, emotional problems and mental health symptoms. Six studies also used process measures to explore different constructs linked to psychological flexibility, the mechanism of change in ACT. There was significant variation in methodological quality across studies.Despite methodological weaknesses across studies, there are some promising results to show support for the use of ACT as a school-based intervention. As existing studies were heterogeneous with regard to design and outcomes measured, this review was unable to draw firm conclusions regarding the efficacy of ACT or the moderating influence of program type, program format or program delivery. More highly powered studies comparing ACT to other active treatments are needed in order to explore these questions further.
AN  - WOS:000828541900001
AU  - Knight,
AU  - L.
AU  - Samuel,
AU  - V.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.jcbs.2022.06.006
L1  - internal-pdf://1959428099/1-s2.0-S2212144722000588-main.cleaned.pdf
PY  - 2022
SP  - 90-105
T2  - Journal of Contextual Behavioral Science
TI  - Acceptance and commitment therapy interventions in secondary schools and their impact on students? mental health and well-being: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000828541900001
UR  - https://www.sciencedirect.com/science/article/pii/S2212144722000588?via%3Dihub
VL  - 25
ER  -
TY  - JOUR
AB  - OBJECTIVES: 
To assess effects of supplementation with 3 or more micronutrients (multiple micronutrients; MMN) compared to no MMN in human milk-fed preterm and low birth weight (LBW) infants. 

RESULTS: 
Data on a subgroup of 414 preterm or LBW infants from 2 randomized controlled trials (4 reports) were included. The certainty of evidence ranged from low to very low. For growth outcomes in the MMN compared to the non-MMN group, there was a small increase in weight-for-age (2 trials, 383 participants) and height-for-age z-scores (2 trials, 372 participants); a small decrease in wasting (2 trials, 398 participants); small increases in stunting (2 trials, 399 participants); and an increase in underweight (2 trials, 396 participants). For neurodevelopment outcomes at 78 weeks, we found small increases in Bayley Scales of Infant Development, Version III (BISD-III), scores (cognition, receptive language, expressive language, fine motor, gross motor) in the MMN compared to the non-MMN group (1 trial, 27 participants). There were no studies examining dose or timing of supplementation. 

CONCLUSIONS: 
Evidence is insufficient to determine whether enteral MMN supplementation to preterm or LBW infants who are fed mother&#039;s own milk is associated with benefit or harm. More trials are needed to generate evidence on mortality, morbidity, growth, and neurodevelopment.
AN  - 35921670
AU  - Kumar,
AU  - M.
AU  - Chowdhury,
AU  - R.
AU  - Sinha,
AU  - B.
AU  - Upadhyay,
AU  - R.
AU  - P.
AU  - Chandola,
AU  - T.
AU  - R.
AU  - Mazumder,
AU  - S.
AU  - Taneja,
AU  - S.
AU  - Edmond,
AU  - K.
AU  - Bahl,
AU  - R.
AU  - Bhandari,
AU  - N.
AU  - Ramakrishnan,
AU  - U.
AU  - Rivera,
AU  - J.
AU  - A.
AU  - Tandon,
AU  - S.
AU  - Duggan,
AU  - C.
AU  - P.
AU  - Liu,
AU  - E.
AU  - Fawzi,
AU  - W.
AU  - Manji,
AU  - K.
AU  - Choudhary,
AU  - T.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1542/peds.2022-057092N
L1  - internal-pdf://4152328398/Kumar-2022-Enteral Multiple Micronutrient Supp.pdf
PY  - 2022
SP  - 01
T2  - Pediatrics
TI  - Enteral Multiple Micronutrient Supplementation in Preterm and Low Birth Weight Infants: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35921670
UR  - https://watermark.silverchair.com/peds_2022057092n.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAvEwggLtBgkqhkiG9w0BBwagggLeMIIC2gIBADCCAtMGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMzSXE-X9AZmcZvORZAgEQgIICpCifZ8lW7-L4DPxu0E5DiT7HNGpwniPxgTfleI03944PUL_F0g8ONRAp8EPHzM1Jv3b4jQmSzwfcR_76rosgIunxocqQUmKsife8Zz0-ejIorspv7kynqbS3Nza1sh5SP-eSMB0tOBCLJlGNjIZHkGuHwUZtORSPJZ2k8PGsnKpdFxuPyi_k9UpFT-qdIAMk2OqvM3ZfE5-CROmZfST1Q43LgoC1JF7rzLMkLBB_mnr3p9F_IDXTX5tFHmilU5aKpFMbHM1bMlfQSEdfbFfvpa56os7T5CRpNx0KRlwMmSIvaKlHP8Wujk1mqt8rhG9IAtWb5MUA8NgWQtSpiaQ2N1zqjdW5DWgHJYwnh0FYXvEjJk3_kr16gYV5Ig8BuHSOZZZx_pH9hyvScKyLKOgg7Pz1z65NitrAbl-sN5A555xeGMhB4t8KfF13RR7vT0gyAVA1DePNxrYy11CqUlVKJv5iAZWzqQlVz2-pAbKc0ehigpzygfSbS5kHOJ98E2cfsHJ4mDQVqNoiiZonn3WJx_PxlDewqZpCnJ3foDHR-hIjXtC2esqXaMQwylG0FTvDInQ3XnlGQUXEaCZQ75jgT83LFVppcSv0lOOhmyyZGZCOCdm4_dPWDxfntamKEZsSPRzXKUr63cFvyr_BI8BXkIkcEQK24bPa2D-sAnZXlcWWd67ICiODvWPHy1KCfkUH49PGFtpKnfnB6FQHZwCyZI1Pwf50zfnnd1UT_MsN-ruUhEpAofgoCqihQZ-iOLfhw7iJ4cDgCbtUjcn_dLM-R66HBwBIFROWlTRECQ2rQBVN-YHHuroU2eUGLJs6O5YOfjlDYTJrv7mfd2_h1Uq7LUESDmstd4wT5KoHpLyOPG2GDl_2_YBLtQlVadOxBs_g7DMxQ-U
VL  - 150
ER  -
TY  - JOUR
AB  - A hospitalized child experiences anxiety more frequently as compared to non-hospitalized children. Surgery can be emotionally distressing for children, and subsequently their parents and caregivers, this distress can cause profound adverse impacts on children. 

We aimed to identify the effect of non-pharmacological interventions on children&#039;s (1-18 years) anxiety undergoing surgery. The following databases: Medical Literature Analysis and Retrieval System Online (MEDLINE), Cumulative Index of Nursing and Allied Health Literature (CINAHL), Proquest, Web&quot; of Science, and Cochrane Central Register of Controlled Trials were systematically searched for full-text articles. 

The review included 15 randomized controlled trials. The risk of bias was assessed using Cochrane Risk of Bias tool. The interventions included in the study were preoperative education, puppet play, therapeutic play, distraction activities, parental presence, and clown therapy. The review presents a narrative reporting of the findings.

This review identifies that non-pharmacological interventions are effective in reducing anxiety among children undergoing surgery. There are a limited number of studies from developing countries. Further research is required to underpin the use of these interventions with children before surgery.
AN  - 35098734
AU  - Mathias,
AU  - E.
AU  - G.
AU  - Pai,
AU  - M.
AU  - S.
AU  - Guddattu,
AU  - V.
AU  - Bramhagen,
AU  - A.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/13674935211062336
L1  - internal-pdf://0902799582/Non-pharmacological interventions to redu-2022.pdf
PY  - 2022
SP  - 13674935211062336
T2  - Journal of Child Health Care
TI  - Non-pharmacological interventions to reduce anxiety among children undergoing surgery: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35098734
ER  -
TY  - JOUR
AB  - Children with autism spectrum disorder (ASD) have been shown to benefit from parent-implemented interventions (PIIs). This meta-analysis improved on prior reviews of PIIs by evaluating RCTs and multiple potential moderators, including indicators of research quality. Fifty-one effect sizes averaged moderately strong overall benefits of PIIs (g = 0.553), with studies having lower risk of research bias yielding lower estimates (g = 0.47). Parent and observer ratings yielded similar averaged estimates for positive behavior/social skills (g = 0.603), language/communication (g = 0.545), maladaptive behavior (g = 0.519), and to a lesser extent, adaptive behavior/life skills (g = 0.239). No other study, intervention, or participant characteristic moderated outcomes. PIIs with children with ASD tend to be effective across a variety of circumstances.
AN  - 35996037
AU  - Cheng,
AU  - W.
AU  - M.
AU  - Smith,
AU  - T.
AU  - B.
AU  - Butler,
AU  - M.
AU  - Taylor,
AU  - T.
AU  - M.
AU  - Clayton,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-022-05688-8
L1  - internal-pdf://4141579010/Cheng-2022-Effects of Parent-Implemented Inter.pdf
PY  - 2022
SP  - 22
T2  - Journal of Autism &amp; Developmental Disorders
TI  - Effects of Parent-Implemented Interventions on Outcomes of Children with Autism: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35996037
UR  - https://link.springer.com/content/pdf/10.1007/s10803-022-05688-8.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - This systematic review aimed to investigate the methodological quality and the effects of fundamental motor skills and physical activity interventions on cognitive and academic skills in 3- to 7-year-old children with special educational needs. The review was reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) statement. A literature search was carried out in April 2020 (updated in January 2022) using seven electronic databases, including ERIC, Scopus, Web of Science, PsycINFO, CINAHL, PubMed, and SPORTDiscus. The methodological quality of the studies was assessed with Effective Public Health Practice Project (EPHPP) Quality Assessment Tool. Cohen&#039;s d effect sizes and post-hoc power analyses were conducted for the included studies. Altogether 22 studies (1883 children) met the inclusion criteria, representing children at-risk for learning difficulties, due to family background (n&lt;sub&gt;studies&lt;/sub&gt; = 8), children with learning difficulties (n&lt;sub&gt;studies&lt;/sub&gt; = 7), learning disabilities (n&lt;sub&gt;studies&lt;/sub&gt; = 5), and physical disabilities (n&lt;sub&gt;studies&lt;/sub&gt; = 2). Two of the included 22 studies displayed strong, one moderate, and 19 studies weak methodological quality. The intervention effects appeared to be somewhat dependent on the severity of the learning difficulty; in cognitive and language skills, the effects were largest in children at-risk due to family background, whereas in executive functions the effects were largest in children with learning disabilities. However, due to the vast heterogeneity of the included studies, and a rather low methodological quality, it is challenging to summarize the findings in a generalizable manner. Thus, additional high-quality research is required to determine the effectiveness of the interventions.
AN  - 36009064
AU  - Jylanki,
AU  - P.
AU  - Mbay,
AU  - T.
AU  - Byman,
AU  - A.
AU  - Hakkarainen,
AU  - A.
AU  - Saakslahti,
AU  - A.
AU  - Aunio,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/brainsci12081001
L1  - internal-pdf://3604184716/Jylanki-2022-Cognitive and Academic Outcomes o.pdf
PY  - 2022
SP  - 28
T2  - Brain Sciences
TI  - Cognitive and Academic Outcomes of Fundamental Motor Skill and Physical Activity Interventions Designed for Children with Special Educational Needs: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36009064
UR  - https://mdpi-res.com/d_attachment/brainsci/brainsci-12-01001/article_deploy/brainsci-12-01001-v3.pdf?version=1659922902
VL  - 12
ER  -
TY  - JOUR
AB  - Evidence shows interventions can improve positive body image in adult women. This systematic review examined the evidence of efficacy of interventions that aimed to increase positive body image in children and young people aged under 18 years. 

The authors followed PRISMA guidelines for the review. Searches of CINAHL Plus, Medline, PsychINFO, Wiley Online Library, SCOPUS and grey literature were conducted up to February 2021 and identified 4171 papers. 

Thirteen studies evaluating 12 interventions, designed for children/adolescents aged 9-18 years, were eligible and evaluated using the Effective Public Health Practice Project (EPHPP) Quality Assessment Tool. The studies evaluated body appreciation, body-esteem, and embodiment. Studies using cognitive dissonance, peer support, and psychoeducation had evidence of improving body appreciation and body-esteem in adolescent girls. 

However, evidence of efficacy for younger children and boys was lacking and the studies ranged in methodological quality. Further research should rigorously evaluate positive body image interventions using second-generation measures that assess specific components of positive body image and consider how to promote positive body image in young children and boys.
AN  - 35679652
AU  - Guest,
AU  - E.
AU  - Zucchelli,
AU  - F.
AU  - Costa,
AU  - B.
AU  - Bhatia,
AU  - R.
AU  - Halliwell,
AU  - E.
AU  - Harcourt,
AU  - D.
DB  - Alerts 6_2022.enl
DO  - /10.1016/j.bodyim.2022.04.009
L1  - internal-pdf://0367117034/1-s2.0-S1740144522000730-main.cleaned.pdf
PY  - 2022
SP  - 58-74
T2  - Body Image
TI  - A systematic review of interventions aiming to promote positive body image in children and adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35679652
UR  - https://www.sciencedirect.com/science/article/pii/S1740144522000730?via%3Dihub
VL  - 42
ER  -
TY  - JOUR
AB  - **Background:** 
Challenging behaviours are common among children and adolescents with intellectual disabilities. Such behaviours often result in poor quality of life outcomes such as physical injury, difficulties with relationships and community integration. 

**Aim:** 
This systematic review aimed to synthesise evidence from studies that assessed the effect of interventions used to reduce/manage challenging behaviour among children with intellectual disabilities in community settings. 

**Methods:** 
Studies published between January 2015 and January 2021 were sought from five electronic databases. The quality of studies was assessed, and a narrative synthesis was conducted. 

**Results:** 
A total of 11 studies were included which utilised various non-pharmacological interventions including multi-model interventions, microswitch technology, cognitive behavioural therapy, art, music and illustrated stories. Microswitch cluster technology was the most used intervention. Studies using pharmacological interventions were not retrieved. Results indicated that a person-centred planning approach was key to offering individualised treatment. 

**Conclusions:** 
The superiority of one intervention or a combination of interventions could not be determined from this review given the heterogeneity of studies. Future research is required to explore the use and effects of pharmacological interventions to compare outcomes and improve quality of care of children with intellectual disabilities. 
(PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-49705-001
AU  - O&#039;Regan,
AU  - O.
AU  - Doyle,
AU  - Y.
AU  - Murray,
AU  - M.
AU  - McCarthy,
AU  - V.
AU  - J.
AU  - Saab,
AU  - M.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/20473869.2022.2052416
L1  - internal-pdf://2971097857/Reducing challenging behaviours among chi-2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - International Journal of Developmental Disabilities
TI  - Reducing challenging behaviours among children and adolescents with intellectual disabilities in community settings: A systematic review of interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-49705-001
UR  - https://www.tandfonline.com/doi/full/10.1080/20473869.2022.2052416
ER  -
TY  - JOUR
AB  - Self-reported effectiveness of electroencephalogram-based neurofeedback (EEG-NF) against the core symptoms of attention-deficit hyperactivity disorder (ADHD) in adolescents/adults remains unclear. 

We searched PubMed, Embase, ClinicalKey, Cochrane CENTRAL, ScienceDirect, Web of Science, and ClinicalTrials.gov from inception to August 2021 for randomized clinical trials (RCTs) of EEG-NF with self-reported ADHD symptom ratings. Comparators included participants on waitlist/treatment as usual (TAU) or receiving other interventions. 

Of the 279 participants (mean age = 23.48; range: 6-60) in five eligible RCTs, 183 received EEG-NF treatment. Forest plot demonstrated no difference in inattention (SMD = -0.11, 95% CI -0.39-0.18, p = 0.46), total score (SMD = -0.08, 95% CI -0.36-0.2, p = 0.56), and hyperactivity/impulsivity (SMD = 0.01, 95% CI -0.23-0.25, p = 0.91) between EEG-NF and comparison groups. Nevertheless, compared with waitlist/TAU, EEG-NF showed better improvement in inattention (SMD = -0.48, 95% CI -0.9--0.06, p = 0.03) but not hyperactivity/impulsivity (SMD = -0.03, 95% CI -0.45-0.38, p = 0.87). Follow-up 6-12 months demonstrated no difference in inattention (SMD = -0.01, 95% CI -0.41-0.38, p = 0.94), total score (SMD = 0.22, 95% CI -0.08-0.52, p = 0.15), and hyperactivity/impulsivity (SMD = -0.01, 95% CI -0.27-0.26, p = 0.96) between the two groups. Dropout rate also showed no difference (RR = 1.05, 95% CI 0.82-1.33, p = 0.72).

 Our results support EEG-NF for improving inattention in adolescents/young adults, although its effectiveness against hyperactivity/impulsivity remains inconclusive.
AN  - 35705685
AU  - Fan,
AU  - H.
AU  - Y.
AU  - Sun,
AU  - C.
AU  - K.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Chung,
AU  - W.
AU  - Tzang,
AU  - R.
AU  - F.
AU  - Chiu,
AU  - H.
AU  - J.
AU  - Ho,
AU  - C.
AU  - N.
AU  - Hung,
AU  - K.
AU  - C.
DB  - Alerts 6_2022.enl
DO  - /10.1038/s41598-022-14220-y
L1  - internal-pdf://3409297419/Fan-2022-A pilot meta-analysis on self-reporte.pdf
PY  - 2022
SP  - 9958
T2  - Scientific Reports
TI  - A pilot meta-analysis on self-reported efficacy of neurofeedback for adolescents and adults with ADHD
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=35705685
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200800/pdf/41598_2022_Article_14220.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - Functioning and quality of life (QOL) are typical outcomes assessed in children and adolescents with major depressive disorder (MDD); however, meta-analytical evidence remains scarce. The aim of this meta-analysis was to assess functioning and QOL antidepressant outcomes in this population. Eight electronic databases (PubMed, Cochrane Library, Web of Science, Embase, CINAHL, PsycINFO, LILACS, and ProQuest Dissertation Abstracts) were searched for double-blind randomized controlled trials (RCTs) up to July 31, 2020. RCTs that compared antidepressants with placebo for treating functioning and QOL in children and adolescents with MDD were included. Primary outcomes were mean change scores of functioning and QOL scales from baseline to post-treatment. Subgroup and sensitivity analyses were conducted to examine whether results were affected by moderator variables (e.g., medication type, age, sample size, and treatment duration). From 7284 publications, we included 17 RCTs (all 17 assessed functioning and 4 assessed QOL outcomes) including 2537 participants. Antidepressants showed significant positive effects on functioning (standardized mean difference [SMD] = 0.17, 95% confidence interval [CI] = 0.09-0.25, p &lt; 0.0001) but not on QOL (SMD = 0.11, 95% CI = -0.02 to 0.24, p = 0.093), with no significant heterogeneity. The subgroup analysis showed that second-generation antidepressants (especially fluoxetine, escitalopram, and nefazodone), but not first-generation antidepressants, led to significant improvements in functioning. Antidepressants (especially second generation) improve functioning but not QOL in children and adolescents with MDD. However, well-designed clinical studies using large samples are needed to confirm these findings. Copyright &copy; 2022, The Author(s).
AN  - 2016498850
AU  - Teng,
AU  - T.
AU  - Zhang,
AU  - Z.
AU  - Yin,
AU  - B.
AU  - Guo,
AU  - T.
AU  - Wang,
AU  - X.
AU  - Hu,
AU  - J.
AU  - Ran,
AU  - X.
AU  - Dai,
AU  - Q.
AU  - Zhou,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1038/s41398-022-01951-9
L1  - internal-pdf://3927129584/Effect of antidepressants on functioning-2022.pdf
PY  - 2022
T2  - Translational Psychiatry
TI  - Effect of antidepressants on functioning and quality of life outcomes in children and adolescents with major depressive disorder: a systematic review and meta-analysis
UR  - http://www.nature.com/tp/index.html
UR  - https://www.nature.com/articles/s41398-022-01951-9.pdf
VL  - 12(1) (no pagination)
ER  -
TY  - JOUR
AB  - **Background**
No consensus on whether physical activity (PA) is related to physical and mental health among pediatric population remains has been reached to date. To further explore their association, our study assessed the effect of PA on physical and mental health of children and adolescents through a systematic review and meta-analysis of randomized controlled studies (RCTs).

**Methods**
Several databases(Web of science, PubMed, Embase, Cochrane Central register of controlled trials, CINAHL) were searched from inception to 1st, December 2020 without language restrictions.

**Results**
38,236 records were identified primitively and 31 included studies with 1,255 participants eventually met our inclusion criteria, all of which exhibited a relatively low-moderate risk of bias of overall quality. In regard to mental health, the administration of PA, compared with the control group, led to moderate improvements in Autism Spectrum Disorder(ASD)[Standard mean difference (SMD) = -0.50, Confidence interval(CI): -0.87, -0.14)] and depression(SMD = -0.68, CI: -0.98, -0.38) among children and adolescents. Similarly, significant result was observed in obesity (SMD = -0.58, CI: -0.80, -0.36). No significant differences were observed in Attention deficit hyperactivity disorder (ADHD) (SMD = -0.29, CI: -0.59, 0.01).

**Conclusion**
Altogether, PA may have a beneficial effect on children and adolescents with ASD, depression and obesity; nevertheless, there is insufficient evidence to confirm its efficacy in ADHD. More large-scale population based randomized controlled trials are needed to explore more reliable evidence between them.
AD  - Peng, Sanying. Department of Physical Education, Hohai University, Nanjing, China.Peng, Sanying. School of Educational Studies, Universiti Sains Malaysia, Penang, Malaysia.Fang, Yuan. College of International Languages and Cultures of Hohai University, Nanjing, China.Othman, Ahmad Tajuddin. School of Educational Studies, Universiti Sains Malaysia, Penang, Malaysia.Liang, Jinghong. Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
AN  - 36533019
AU  - Peng,
AU  - S.
AU  - Fang,
AU  - Y.
AU  - Othman,
AU  - A.
AU  - T.
AU  - Liang,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyg.2022.940977
DP  - Ovid Technologies
J2  - Front Psychol
L1  - internal-pdf://2265274119/fpsyg-13-940977.cleaned.pdf
LA  - English
M3  - Systematic Review
N1  - Peng, SanyingFang, YuanOthman, Ahmad TajuddinLiang, Jinghong
PY  - 2022
SP  - 940977
T2  - Frontiers in Psychology
TI  - Meta-analysis and systematic review of physical activity on neurodevelopment disorders, depression, and obesity among children and adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=36533019
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36533019&amp;id=doi:10.3389%2Ffpsyg.2022.940977&amp;issn=1664-1078&amp;isbn=&amp;volume=13&amp;issue=&amp;spage=940977&amp;pages=940977&amp;date=2022&amp;title=Frontiers+in+Psychology&amp;atitle=Meta-analysis+and+systematic+review+of+physical+activity+on+neurodevelopment+disorders%2C+depression%2C+and+obesity+among+children+and+adolescents.&amp;aulast=Peng&amp;pid=%3Cauthor%3EPeng+S%3C%2Fauthor%3E%3CAN%3E36533019%3C%2FAN%3E%3CDT%3ESystematic+Review%3C%2FDT%3E
VL  - 13
ER  -
TY  - JOUR
AB  - **Background**
With the popularity of computers, the internet, and the global spread of COVID-19, more and more attention deficit hyperactivity disorder (ADHD) patients need timely interventions through the internet. At present, there are many online intervention schemes may help these patients. It is necessary to integrate data to analyze their effectiveness. 

**Objectives**
Our purpose is to integrate the ADHD online interventions trials, study its treatment effect and analyze its feasibility, and provide reference information for doctors in other institutions to formulate better treatment plans. 

**Methods**
We searched PubMed, EMBASE and Cochrane libraries. We didn&#039;t limit the start date and end date of search results. Our last search was on December 1, 2021. The keyword is ADHD online therapy. We used the Cochrane bias risk tool to assess the quality of included studies, used the standardized mean difference (SMD) as an effect scale indicator to measure data. Random effects model, subgroup analysis were used to analyze the data. 

**Results**
Six randomized controlled trials (RCTs) were identified, including 261 patients with ADHD. These studies showed that online interventions was more effective than waiting list in improving attention deficit and social function of adults and children with ADHD. The attention deficit scores of subjects were calculated in six studies. The sample size of the test group was 123, the sample size of the control group was 133, and the combined SMD was -0.73 (95% confidence interval: -1.01, -0.44). The social function scores of subjects were calculated in six studies. The sample size of the experimental group was 123 and the control group was 133. The combined SMD was -0.59 (95% confidence interval: -0.85, -0.33). 

**Conclusions**
The results show that online interventions of ADHD may be an effective intervention. In the future, we need more online intervention researches to improve the symptoms of different patients, especially for some patients who have difficulties in accepting face-to-face treatment.
AN  - 35837629
AU  - Shou,
AU  - S.
AU  - Xiu,
AU  - S.
AU  - Li,
AU  - Y.
AU  - Zhang,
AU  - N.
AU  - Yu,
AU  - J.
AU  - Ding,
AU  - J.
AU  - Wang,
AU  - J.
DB  - Alerts 6_2022.enl
DO  - /10.3389/fpsyg.2022.854810
L1  - internal-pdf://0534564842/Shou-2022-Efficacy of Online Intervention for.pdf
PY  - 2022
SP  - 854810
T2  - Frontiers in Psychology
TI  - Efficacy of Online Intervention for ADHD: A Meta-Analysis and Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35837629
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274127/pdf/fpsyg-13-854810.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - &quot;Attachment and Biobehavioural Catch-Up&quot; (ABC) is a 10 session home visiting program, grounded in attachment theory. It aims to improve child emotion regulation, attachment and behavioral outcomes through changing caregivers&#039; attachment related behaviors. There is increasing evidence with respect to the effectiveness of ABC in producing positive child outcomes, but the intervention&#039;s direct effect on parent outcomes remains unclear. 

This review examined the association of ABC with attachment related parent outcomes. The PubMed, EMBASE, PyschINFO and SCOPUS databases were searched for relevant studies in August 2021, and again in April 2022. The eligibility criteria for included studies were (1) infants aged 0-27 months at time of the ABC intervention, (2) &quot;at risk&quot; parents, (3) controlled trials published in peer-reviewed journals and (4) utilized a measure of attachment related parent outcomes. 

Eleven eligible studies were included. The findings showed ABC had a significant small to medium effect on a variety of attachment related parent outcomes among parents presenting with multiple psychosocial risk factors. &quot;Sensitivity&quot; was measured most frequently, with small to medium main effect sizes recorded at follow-up, compared to controls. Implications for the clinical effectiveness of the ABC program in community settings are discussed. 

Future research should clarify who ABC is most effective for and how it compares to similar interventions.
AD  - O&#039;Byrne, Emma. School of Applied Psychology, University College Cork, Cork, Ireland.McCusker, Chris. School of Applied Psychology, University College Cork, Cork, Ireland.McSweeney, Shane. School of Applied Psychology, University College Cork, Cork, Ireland.
AN  - 36565696
AU  - O&#039;Byrne,
AU  - E.
AU  - McCusker,
AU  - C.
AU  - McSweeney,
AU  - S.
DA  - Dec 24
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/imhj.22025
DP  - Ovid Technologies
J2  - Infant Ment Health J
L1  - internal-pdf://1561745003/Infant Mental Health Journal - 2022 - O Byrne.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDecO&#039;Byrne, EmmaMcCusker, ChrisMcSweeney, Shane
PY  - 2022
SP  - 24
T2  - Infant Mental Health Journal
TI  - The impact of the &quot;Attachment and Biobehavioural Catch-Up&quot; program on attachment related parent behavior-A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36565696
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36565696&amp;id=doi:10.1002%2Fimhj.22025&amp;issn=0163-9641&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2022&amp;title=Infant+Mental+Health+Journal&amp;atitle=The+impact+of+the+%22Attachment+and+Biobehavioural+Catch-Up%22+program+on+attachment+related+parent+behavior-A+systematic+review.&amp;aulast=O%27Byrne&amp;pid=%3Cauthor%3EO%27Byrne+E%3C%2Fauthor%3E%3CAN%3E36565696%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 24
ER  -
TY  - JOUR
AB  - Individuals with autism spectrum disorder (ASD) struggle accessing psychotherapy services for comorbidities, including anxiety-, depressive- and obsessive-compulsive disorders (OCD). Apart from cognitive behavioural therapy (CBT) for anxiety in children with ASD, it is unclear whether psychotherapy is effective for these comorbid disorders. We therefore systematically reviewed any form of psychotherapy for co-occurring symptoms of anxiety, depression and OCD in individuals with ASD.Database searches were conducted until February 2022 using EMBASE, PsycINFO and PubMed. Randomised controlled trials (RCT) were included investigating any form of psychotherapy for symptoms of anxiety, depression and OCD in individuals with ASD. Summary data were extracted, and random-effects meta-analyses were conducted.For CBT 26 RCTs (n = 1251), and for social skills training (SST) 11 RCTs (n = 475) met criteria for inclusion. Pooled effect sizes indicated a moderate reduction of anxiety in children (g = -0.70) and a small reduction of depressive symptoms in adults (g = -0.39). For SST overall effect sizes were small for reduction of anxiety in children (g = -0.35) and adults (g = -0.34) and moderate for reduction of depressive symptoms in children (g = -0.50). Risk of bias was high in 18, moderate in 16 and low in 3 RCTs.Our results provide new and age-specific evidence that: (1) CBT is effective for reducing anxiety in children and to a lesser extent for depressive symptoms in adults with ASD; and (2) social skills interventions are effective for reducing anxiety in children and adults and for depressive symptoms in children with ASD.
AN  - 36404645
AU  - Wichers,
AU  - R.
AU  - H.
AU  - van
AU  - der
AU  - Wouw,
AU  - L.
AU  - C.
AU  - Brouwer,
AU  - M.
AU  - E.
AU  - Lok,
AU  - A.
AU  - Bockting,
AU  - C.
AU  - L.
AU  - H.
DB  - Alerts 6_2022.enl
DO  - /10.1017/S0033291722003415
L1  - internal-pdf://0022404869/Wichers-2022-Psychotherapy for co-occurring sy.pdf
PY  - 2022
SP  - 1-17
T2  - Psychological Medicine
TI  - Psychotherapy for co-occurring symptoms of depression, anxiety and obsessive-compulsive disorder in children and adults with autism spectrum disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36404645
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/7FEA93E91B99E3E50619E69CA3C293D5/S0033291722003415a.pdf/div-class-title-psychotherapy-for-co-occurring-symptoms-of-depression-anxiety-and-obsessive-compulsive-disorder-in-children-and-adults-with-autism-spectrum-disorder-a-systematic-review-and-meta-analysis-div.pdf
ER  -
TY  - JOUR
AB  - Behaviour parent training (BPT) is known to effectively reduce child externalising problems. However, evidence for BPT to have secondary benefits for reducing internalising symptoms remains unclear. 

To address this, electronic databases (PsycINFO, MEDLINE, EMBASE, CINAHL, and SCOPUS) were systematically searched for studies examining internalising outcomes from BPT among children aged 2-12 years with clinically elevated externalizing problems. Outcomes for internalising problems following BPT were analysed by meta-analysis. 

Of 9105 studies identified, 24 studies met the eligibility criteria. Results from meta-analysis demonstrated a significant small treatment effect size (g = - 0.41) for reducing internalising symptoms immediately after treatment. Studies showed moderate heterogeneity (I&lt;sup&gt;2&lt;/sup&gt; = 44%). Moderation analyses indicated that the overall treatment effect was robust against variations in treatment and study design characteristics. However, a review of individual study methods indicate that these results are limited by significant heterogeneity and limitations in clinical assessment. 

Overall, the results suggest that BPT programmes for reducing externalising problems have the potential to improve internalising outcomes, but that there is limited information to determine the reliability of these effects, highlighting the need for further investigation.
AD  - Bloss, Christy. Department of Clinical Psychology, School of Health in Social Science, University of Edinburgh, Edinburgh, UK.Brown, Sophie. Department of Clinical Psychology, School of Health in Social Science, University of Edinburgh, Edinburgh, UK.Sawrikar, Vilas. Department of Clinical Psychology, School of Health in Social Science, University of Edinburgh, Edinburgh, UK. vilas.sawrikar@ed.ac.uk.Sawrikar, Vilas. Centre of Applied Developmental Psychology, University of Edinburgh, Edinburgh, UK. vilas.sawrikar@ed.ac.uk.
AN  - 36527525
AU  - Bloss,
AU  - C.
AU  - Brown,
AU  - S.
AU  - Sawrikar,
AU  - V.
DA  - Dec 17
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s00787-022-02122-3
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
L1  - internal-pdf://1349406191/Bloss-2022-Does behavioural parent training re.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDecBloss, ChristyBrown, SophieSawrikar, Vilas
PY  - 2022
SP  - 17
T2  - European Child &amp; Adolescent Psychiatry
TI  - Does behavioural parent training reduce internalising symptoms (or not) among children with externalising problems? Systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36527525
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36527525&amp;id=doi:10.1007%2Fs00787-022-02122-3&amp;issn=1018-8827&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2022&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=Does+behavioural+parent+training+reduce+internalising+symptoms+%28or+not%29+among+children+with+externalising+problems%3F+Systematic+review+and+meta-analysis.&amp;aulast=Bloss&amp;pid=%3Cauthor%3EBloss+C%3C%2Fauthor%3E%3CAN%3E36527525%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s00787-022-02122-3.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - **Purpose** 
The purposes of this systematic review were to systematically summarize components in existing school-based child sexual abuse (CSA) prevention programs and identify predictors for program effectiveness. 

**Method** 
Building upon the most comprehensive systematic review on this topic, we conducted systematic searches in both English-language from September 2014 to October 2020 and Chinese-language from inception to October, 2020. Meta-regressions were performed to identify predictors for program effectiveness. 

**Results** 
Thirty-one studies were included with a total sample size of 9049 participants. Results from meta-analyses suggested that interventions are effective in increasing participants&#039; CSA knowledge as assessed via questionnaires (g = 0.72, 95% CI [0.52-0.93]) and vignette-based measures (g = 0.55, 95% CI [0.35-0.74]). Results from meta-regression suggested that interventions with more than three sessions are more effective than interventions with fewer sessions. Interventions appear to be more effective with children who are 8 years and older than younger children. 

**Discussion** 
CSA is a global issue that has significant negative effects on victims&#039; physical, psychological, and sexual well-being. Our findings also provide recommendations for future research, particularly in terms of optimizing the effectiveness of school-based CSA prevention programs, and the better reporting of intervention components as well as participant characteristics.
AN  - WOS:000822293100001
AU  - Lu,
AU  - M.
AU  - Y.
AU  - Barlow,
AU  - J.
AU  - Meinck,
AU  - F.
AU  - Walsh,
AU  - K.
AU  - Wu,
AU  - Y.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/10497315221111393
L1  - internal-pdf://3847259318/Lu-School-based Child Sexual Abuse Interventio.pdf
PY  - 2022
SP  - 23
T2  - Research on Social Work Practice
TI  - School-based Child Sexual Abuse Interventions: A Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000822293100001
UR  - https://journals.sagepub.com/doi/pdf/10.1177/10497315221111393
ER  -
TY  - JOUR
AB  - BAKGRUNN:
Mestringskatten er et manualbasert program for behandling av barn og ungdom med angstplager eller angstlidelser. Tiltaket foreligger i to versjoner; Mestringskatten (7&ndash;13 år) og Mestringskatten for ungdom (14&ndash;17 år). Barneversjonen omfatter 12 samlinger, mens ungdomsversjonen består av 14 samlinger. Begge versjonene inkluderer i tillegg to foreldresamlinger. Målgruppen for tiltaket er unge med separasjonsangstlidelse, sosial angstlidelse og/eller generalisert angstlidelse. Tiltaket kan gjennomføres både som individuell behandling og som gruppebehandling. Rettighetshaver i Norge er Universitetsforlaget (www.universitetsforlaget.no). Foreliggende artikkel er en revidert versjon av tidligere evalueringer av samme tiltak i Ungsinn (Bratt, 2010; Haugland og Bjåstad, 2017).

METODE:
Kunnskapsoppsummeringen bygger på to systematiske litteratursøk gjennomført i henholdsvis 2016 og 2020 i databasene Mbase, Medline, Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS, SweMed, Kunnskapssenteret, NREPP, NICE, Blueprint og CEBC. Det er i tillegg innhentet informasjon fra fagansvarlige for programmet ved RBUP Øst og Sør.

RESULTATER:
Resultatene omfatter en oppsummering av tiltakets beskrivelse, forskningsstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Tiltakets bakgrunn, innhold og metoder er godt beskrevet gjennom strukturerte og detaljerte terapeutmanualer og arbeidsbøker. Tiltaket har god teoretisk forankring. Det foreligger en rekke kvalitetsmessig gode internasjonale effektstudier og metaanalyser av barneversjonen av det opprinnelige amerikanske tiltaket (Coping Cat), hvor effekt av tiltaket er godt dokumentert. Det har vært gjennomført en effektivitetsstudie av Mestringskatten i Norge med pasienter (7&ndash;13 år) fra ordinære barne- og ungdomspsykiatriske klinikker. Resultatene viste effekt av Mestringskatten sammenlignet med venteliste, for eksempel ved tap av primær angstdiagnose. Både individuell behandling og gruppebehandling med Mestringskatten hadde effekt. Barn med sosial angstlidelse viste større sannsynlighet for bedring etter gruppebehandling sammenlignet med individuell behandling. Resultatene av behandlingen ble opprettholdt ved 2 års oppfølging. Deltakere og terapeuter rapporterte tilfredshet med tiltaket. Det er ingen krav til opplæring, kvalifikasjoner eller prosedyrer for å sikre tilstrekkelig implementeringskvalitet ved bruk av programmet. Internasjonalt er det begrenset evidens for ungdomsmanualen og vi fant ingen nordiske studier som har evaluert effekten av Mestringskatten for ungdom.

KONKLUSJON:
Mestringskatten og Mestringskatten for ungdom er tiltak med god teoretisk forankring. Tiltakene er godt beskrevet. Mestringskatten har dokumentert effekt ved en norsk effektivitetsstudie av høy kvalitet blant barn (7&ndash;13 år) rekruttert fra klinikker innen barn- og unges psykiske helsevern i Norge. Resultatene antas å ha god overføringsverdi til vanlig klinisk praksis. Tiltaket har vist effekt i en rekke internasjonale studier og kunnskapsoppsummeringer. Det foreligger ingen nordiske studier på effekten av Mestringskatten for ungdom. Manglende systematisk oppfølging av implementering av tiltaket bidrar til usikkerhet om kvaliteten på behandlingen når Mestringskatten og Mestringskatten for ungdom benyttes i vanlig praksis i Norge.

Tiltaket benyttet for barn (7-13 år) klassifiseres på evidensnivå 4: Tiltak med tilfredsstillende dokumentasjon på effekt.

Tiltaket benyttet for ungdom (14&ndash;17 år) klassifiseres på evidensnivå 3: Tiltak med noe dokumentasjon på effekt.
AU  - Haugland,
AU  - B.
AU  - S.,
AU  - Bjåstad,
AU  - J.
AU  - F.,
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - Tom verdi
PY  - 2022
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Mestringskatten (3. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/mestringskatten-3-utg/
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
To evaluate the effectiveness of group cognitive-behavioral therapy (GCBT) for the treatment of adolescents with obsessive compulsive disorder (OCD). 

**METHODS**
This review was registered in PROSPERO under number CRD42020158475. Five databases (PubMed, Virtual Health Library, Web of Science, Scopus, and PsycINFO) were searched. After applying the inclusion and exclusion criteria, 13 studies were analyzed in the qualitative synthesis (i.e., systematic review) and eight in the quantitative synthesis (i.e., meta-analysis). For the latter, fixed-effect modeling was used to assess the primary outcome (i.e., OCD symptoms). 

**RESULTS**
The main findings suggest that GCBT is effective in reducing the symptoms of OCD in adolescents (d = -1.32). However, these results must be interpreted with caution, since all of the included studies showed some bias in their design. 

**CONCLUSIONS**
 GCBT is effective in reducing OCD symptoms in adolescents.
AN  - 35749639
AU  - Bortoncello,
AU  - C.
AU  - F.
AU  - Cardoso,
AU  - N.
AU  - O.
AU  - Salvador,
AU  - E.
AU  - Z.
AU  - de
AU  - Avila,
AU  - R.
AU  - C.
AU  - Machado,
AU  - W.
AU  - L.
AU  - Ferrao,
AU  - Y.
AU  - A.
DB  - Alerts 6_2022.enl
DO  - /10.47626/1516-4446-2021-2264
L1  - internal-pdf://2831792953/rbp20212264.cleaned.pdf
PY  - 2022
SP  - 23
T2  - Revista Brasileira de Psiquiatria
TI  - Efficacy of group cognitive-behavioral therapy in adolescents with obsessive compulsive disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35749639
VL  - 23
ER  -
TY  - JOUR
AB  - Vesicular monoamine transporter type 2 (VMAT2) inhibitors may be an effective therapy for chronic tic disorders (CTD), including Tourette syndrome (TS), but there has not been a meta-analysis compiling available evidence from randomized controlled trials (RCTs). We performed a systematic review and meta-analysis to evaluate the efficacy, acceptability, and tolerability of VMAT2 inhibitors for CTD/TS. PubMed, CENTRAL, and Embase were searched for double-blinded RCTs of VMAT2 inhibitors versus placebo for the treatment of CTD/TS. Change in tic severity measured by the Yale Global Tic Severity Scale (efficacy) and rates of discontinuation attributed to adverse effects (tolerability) or all causes (acceptability) were extracted closest to 12 weeks. Mean difference (MD) and odds ratio (OR) were the effect size indexes for efficacy and acceptability/tolerability, respectively. Data were pooled through random-effects meta-analysis weighted by inverse variance. Five RCTs involving eight comparisons were included. Meta-analysis found a nonsignificant effect on efficacy (k = 8; N = 583; MD = -0.71; 95% confidence interval [CI], -1.93 to 0.50; P = 0.24), and there was certainty that the true effect is nonclinically meaningful (high quality of evidence). Meta-analysis found decreased tolerability (k = 7; N = 626; OR = 2.67; 95% CI, 1.21-5.92; P = 0.01) and decreased acceptability (k = 8; N = 626; OR = 1.90; 95% CI, 1.14-3.18; P = 0.01), although those comparisons were limited because of the relatively small number of events across trials. Meta-analyses did not support the efficacy of VMAT2 inhibitors in the short-term treatment of tic disorders and suggested no clinically meaningful effect of these agents on tic symptoms. (c) 2022 International Parkinson and Movement Disorder Society
AN  - WOS:000758937700001
AU  - Behling,
AU  - E.
AU  - Farhat,
AU  - L.
AU  - C.
AU  - Landeros-Weisenberger,
AU  - A.
AU  - Bloch,
AU  - M.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/mds.28957
L1  - internal-pdf://0156255378/Meta-Analysis_ Efficacy and Tolerability of Ve.pdf
PY  - 2022
SP  - 11
T2  - Movement Disorders
TI  - Meta-Analysis: Efficacy and Tolerability of Vesicular Monoamine Transporter Type 2 Inhibitors in the Treatment of Tic Disorders
UR  - &lt;Go to ISI&gt;://WOS:000758937700001
ER  -
TY  - JOUR
AB  - This article reviews 12 meta-analyses of universal, school-based social and emotional learning (SEL) programs for children from early childhood education through high school. The aims were to assess the breath and consistency of outcomes across meta-analyses and the potential influence of different moderators (i.e., individual, programmatic, ecological, and methodological) on program impacts. Collectively, the meta-analyses were rated to be high quality and included 523 unique reports conducted in many countries and involving an estimated 1 million students. Mean effects were consistently statistically significant across reviews on a range of outcomes including increased SEL skills, attitudes, prosocial behaviors, and academic achievement, and decreased conduct problems and emotional distress (post ds ranged from 0.09 to 0.70 and follow-up ds ranged from 0.07 to 0.33 depending on the outcome and the specific review). However, there was little consistency regarding the moderators examined, or findings when the same moderators were assessed across reviews. Moreover, there is little information on possible interactions between moderators. Research has yet to clarify which individual, contextual, methodological, and programmatic variables promote or hinder the development of different SEL skills for diverse school-aged children and youth. Recommendations to guide future research in identifying the conditions and mechanisms by which SEL programs are most effective are provided. (PsycInfo Database Record (c) 2023 APA, all rights reserved) Impact Statement Public Significance Statement-This review of 12 meta-analyses, involving an estimated 1 million students from early childhood education through high school, shows that social and emotional learning (SEL) programs have consistent, positive impacts on a broad range of student outcomes including increased SEL skills, attitudes, prosocial behaviors, and academic achievement and decreased conduct problems and emotional distress. However, there is little consistency regarding conditions and mechanisms by which these programs are most effective. By summarizing the substantial evidence base for SEL programs, and offering recommendations for future work, this article will stimulate more research and practice related to such initiatives. (PsycInfo Database Record (c) 2023 APA, all rights reserved)
AN  - 2023-55252-001
AU  - Durlak,
AU  - J.
AU  - A.
AU  - Mahoney,
AU  - J.
AU  - L.
AU  - Boyle,
AU  - A.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/bul0000383
L1  - internal-pdf://0062168769/Durlak.pdf
PY  - 2022
SP  - 765-782
T2  - Psychological Bulletin
TI  - What we know, and what we need to find out about universal, school-based social and emotional learning programs for children and adolescents: A review of meta-analyses and directions for future research
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc21&amp;AN=2023-55252-001
VL  - 148
ER  -
TY  - JOUR
AB  - Animal-assisted therapy has become a fast-growing and effective approach for remediating core impairments of children with ASD; however, recent systematic review studies on the effects of AAT in children with ASD have some limitations, including referral to a variety of animal-assisted interventions rather than to horseback-riding therapy alone and the absence of any meta-analysis in systematic reviews. A complete systematic review of the studies that describe the use of THR as an intervention is needed to specifically target the core impairments of children with ASD. The purpose of this study was to employ the systematic review method to synthesize research findings regarding the effects of THR programs on the social interaction and communication skills of children with ASD. We conducted a structured search in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched for potentially relevant studies in five databases (Web of Science, PubMed, CINAHL, Scopus, and SPORTDiscus) from inception until February 2022. In addition, we manually searched the bibliographies of the included studies to find articles that might otherwise have been missed. We considered articles eligible or ineligible if they satisfied specific inclusion or exclusion criteria. Our results showed that the THR program is an effective direct and alternative therapeutic program that can considerably improve the social behaviors and communication skills of children with ASD and can effectively impact autistic impairments in areas such as social awareness, social cognition, social motivation, and social communication. These findings are in line with those of previous studies; however, we did not find statistical evidence of any effect of THR on the autistic behaviors of irritability, stereotypy, and inappropriate speech. In conclusion, the findings produced by this meta-analysis study provide evidence that THR programs can considerably improve the social behaviors and communication skills of children with ASD.
AN  - 36361327
AU  - Chen,
AU  - S.
AU  - Zhang,
AU  - Y.
AU  - Zhao,
AU  - M.
AU  - Du,
AU  - X.
AU  - Wang,
AU  - Y.
AU  - Liu,
AU  - X.
DB  - Alerts 6_2022.enl
DO  - /10.3390/ijerph192114449
L1  - internal-pdf://1296089513/Chen-2022-Effects of Therapeutic Horseback-Rid.pdf
PY  - 2022
SP  - 04
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Effects of Therapeutic Horseback-Riding Program on Social and Communication Skills in Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36361327
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-19-14449/article_deploy/ijerph-19-14449.pdf?version=1667549195
VL  - 19
ER  -
TY  - JOUR
AB  - **Aim:** 
There is insufficient evidence regarding the efficacy and safety of stem cell therapy for autism spectrum disorders. We performed the first meta-analysis of stem cell therapy for autism spectrum disorders in children to provide evidence for clinical rehabilitation. 

**Methods:** 
The data source includes PubMed/Medline, Web of Science, EMBASE, Cochrane Library and China Academic Journal, from inception to 24th JULY 2021. After sifting through the literature, the Cochrane tool was applied to assess the risk of bias. Finally, we extracted data from these studies and calculated pooled efficacy and safety. 

**Results:** 
5 studies that met the inclusion criteria were included in current analysis. Meta-analysis was performed using rehabilitation therapy as the reference standard. Data showed that the Childhood Autism Rating Scale score of stem cell group was striking lower than the control group (WMD: -5.96; 95%CI [-8.87, -3.06]; p &lt; 0.0001). The Clinical Global Impression score consolidated effect size RR = 1.01, 95%CI [0.87, 1.18], Z = 0.14 (p = 0.89), the effective rate for The Clinical Global Impression was 62% and 60% in the stem cell group and the control group, respectively. The occurrence events of adverse reactions in each group (RR = 1.55; 95%CI = 0.60 to 3.98; p = 0.36), there was no significant difference in the incidence of adverse reactions between the stem cell group and the control group. 

**Conclusions:**
The results of this meta-analysis suggested that stem cell therapy for children with autism might be safe and effective. However, the evidence was compromised by the limitations in current study size, lacking standardized injection routes and doses of stem cells, as well as shortages in diagnostic tools and long period follow-up studies. Hence, it calls for more studies to systematically confirm the efficacy and safety of stem cell therapy for children with autism spectrum disorders.
AN  - 35601435
AU  - Qu,
AU  - J.
AU  - Liu,
AU  - Z.
AU  - Li,
AU  - L.
AU  - Zou,
AU  - Z.
AU  - He,
AU  - Z.
AU  - Zhou,
AU  - L.
AU  - Luo,
AU  - Y.
AU  - Zhang,
AU  - M.
AU  - Ye,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fped.2022.897398
L1  - internal-pdf://1354312780/Efficacy and Safety of Stem Cell Therapy-2022.pdf
PY  - 2022
SP  - 897398
T2  - Frontiers in Pediatrics
TI  - Efficacy and Safety of Stem Cell Therapy in Children With Autism Spectrum Disorders: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35601435
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114801/pdf/fped-10-897398.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **Background** 
Suicidal ideation is an increasingly common presentation to the paediatric emergency department. The presence of suicidal ideation is linked to acute psychiatric hospital admission and increased risk of suicide. The paediatric emergency department plays a critical role in reducing risk of suicide, strengthening protective factors and encouraging patient engagement with ongoing care. 

**Aims** 
This rapid review aims to synthesise evidence on interventions that can be implemented in the paediatric emergency department for children and adolescents presenting with suicidal ideation. 

**Method** 
Six electronic databases were searched for studies published since January 2010: PubMed, Web of Science, Medline, PsycINFO, CINAHL and Cochrane. Outcomes of interest included suicidal ideation, engagement with out-patient services, incidence of depressive symptoms, hopelessness, family empowerment, hospital admission and feasibility of interventions. The Cochrane risk-of-bias tool was used to evaluate the quality of studies. 

**Results** 
Six studies of paediatric emergency department-initiated family-based (n = 4) and motivational interviewing interventions (n = 2) were narratively reviewed. The studies were mainly small and of varying quality. The evidence synthesis suggests that both types of intervention, when initiated by the paediatric emergency department, reduce suicidal ideation and improve patient engagement with out-patient services. Family-based interventions also showed a reduction in suicidality and improvement in family empowerment, hopelessness and depressive symptoms. 

**Conclusions** 
Paediatric emergency department-initiated interventions are crucial to reduce suicidal ideation and risk of suicide, and to enhance ongoing engagement with out-patient services. Further research is needed; however, family-based and motivational interviewing interventions could be feasibly and effectively implemented in the paediatric emergency department setting. Copyright &copy; 2022 The Author(s). Published by Cambridge University Press on behalf of the Royal College of Psychiatrists.
AN  - 2017136470
AU  - Virk,
AU  - F.
AU  - Waine,
AU  - J.
AU  - Berry,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/bjo.2022.21
L1  - internal-pdf://3266995178/A rapid review of emergency department in-2022.pdf
PY  - 2022
T2  - BJPsych Open
TI  - A rapid review of emergency department interventions for children and young people presenting with suicidal ideation
UR  - https://www.cambridge.org/core/journals/bjpsych-open
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/9B3854A523D1E2B1782DFC4B9B5CAFB4/S2056472422000217a.pdf/div-class-title-a-rapid-review-of-emergency-department-interventions-for-children-and-young-people-presenting-with-suicidal-ideation-div.pdf
VL  - 8(2) (no pagination)
ER  -
TY  - JOUR
AB  - Mindfulness-based programs are a promising intervention modality for reducing disruptive behavior, and Soles of the Feet (SOF) is one program that teaches internal awareness of personal events (e.g., unpleasant emotions) and a self-regulation strategy to decrease disruptive behaviors. This study conducted a meta-analysis of single-case research design (SCRD) studies that implemented SOF to decrease disruptive behaviors. Existing SOF studies were evaluated using high-quality SCRD standards, resulting in 15 studies included in the analysis (49 participants; mean age 23.12 years (SD = 15.87); highly heterogeneous backgrounds). Studies were analyzed to calculate effect sizes using Tau-U, an innovative non-parametric statistical approach for estimating effect sizes in SCRD studies. The aggregated weighted Tau-U effect size of SOF across all studies was -0.87. Moderator analyses indicated SOF&#039;s effectiveness was robust across participant characteristics and delivery formats. This meta-analysis suggests that SOF is a moderately effective evidence-based practice for reducing disruptive behavior.
AN  - WOS:000753028800001
AU  - Felver,
AU  - J.
AU  - C.
AU  - Clawson,
AU  - A.
AU  - J.
AU  - Ash,
AU  - T.
AU  - L.
AU  - Martens,
AU  - B.
AU  - K.
AU  - Wang,
AU  - Q.
AU  - Singh,
AU  - N.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/01454455211073738
L1  - internal-pdf://1658714348/Meta-Analysis of Mindfulness-Based Program Sol.pdf
PY  - 2022
SP  - 29
T2  - Behavior Modification
TI  - Meta-Analysis of Mindfulness-Based Program Soles of the Feet for Disruptive Behaviors
UR  - &lt;Go to ISI&gt;://WOS:000753028800001
UR  - https://journals.sagepub.com/doi/pdf/10.1177/01454455211073738
ER  -
TY  - JOUR
AB  - Electroconvulsive therapy (ECT) is a well-established treatment for adults with mood disorders. However, its use in child and adolescent populations is less common. At the same time, approximately 60% of child and adolescent patients do not respond satisfactorily to first-line treatments for mood disorders. 

Given the need for effective treatments for severe mood disorders in adolescents and the low use rate of ECT, this systematic review examines the existing literature on the effectiveness and adverse effect profile of ECT when used for treatment-resistant mood disorders in children and adolescents. Searches were conducted in Medline, Embase, and PsycInfo using search terms related to (1) children and adolescents, (2) mood disorders, and (3) ECT. Searches identified 1715 unique articles. The full text of 71 selected articles were reviewed, leading to 41 studies included in the study. A standardized data extraction tool was used to collect key information from each study (i.e. author and publication year, objectives, participants and setting, design, measures, clinical outcomes, and side effects). 

As most of the studies found were case series, the Joanna Briggs Institute Case Series Critical Appraisal tool was used to assess quality. Studies were summarized qualitatively by comparing findings across key study parameters. Our review identified 41 studies for inclusion. Twenty were case series, two were case-control studies, and nineteen were case reports. Overall treatment response rates ranged from 51 to 92%, with patients receiving an average of 12 treatments. Among studies with n &gt; 30, response rates were largely 70-82% for depression and 87-90% for mania. Seven studies used the Mini-Mental State Exam and found no evidence of significant post-treatment cognitive impairment. The majority of side effects were minor and transient. Tardive seizure was reported in 4 (0.6%) patients. ECT was discontinued early due to side effects in 11 (1.5%) cases. No fatalities were reported.

Our data suggest that ECT is safe and effective for the treatment of mood disorders in child and adolescent populations, and should be considered in severe and treatment-refractory cases. Controlled studies with objective measures and long-term follow-up are needed to advance the evidence base.
AN  - WOS:000740592000001
AU  - Castaneda-Ramirez,
AU  - S.
AU  - Becker,
AU  - T.
AU  - D.
AU  - Bruges-Boude,
AU  - A.
AU  - Kellner,
AU  - C.
AU  - Rice,
AU  - T.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-022-01942-7
L1  - internal-pdf://3018495020/Systematic review_ Electroconvulsive therapy f.pdf
PY  - 2022
SP  - 32
T2  - European Child &amp; Adolescent Psychiatry
TI  - Systematic review: Electroconvulsive therapy for treatment-resistant mood disorders in children and adolescents
UR  - &lt;Go to ISI&gt;://WOS:000740592000001
UR  - https://link.springer.com/content/pdf/10.1007/s00787-022-01942-7.pdf
ER  -
TY  - JOUR
AB  - **Objectives**
Interventions involving kindness- and compassion-based meditation (KCBM) have been shown to have various benefits for adults, and there is growing interest in using KCBMs with children. This systematic review explores the effects of KCBM on wellbeing, prosociality, and cognitive functioning in children and adolescents. 

**Methods**
Studies were eligible if they examined interventions that contained a proportion of KCBM above a set threshold, included child participants only, used any or no control group, and included at least one outcome measure related to wellbeing, prosociality, or cognitive functioning. Studies were assessed for quality using the Quality Assessment Tool for Quantitative Studies, and findings were synthesised narratively. 

**Results**
A systematic literature search of 11 databases up to February 2020 identified 3,073 papers. Ten studies were eligible for inclusion in the review, including 807 children. There was evidence of improvements in wellbeing in 47% of wellbeing outcome measures (including stress, anxiety, depression, negative affect, markers of inflammation, mindfulness, and self-compassion). Prosociality and cognitive functioning (visual perception and motor accuracy) were examined in 1 study each, and there was evidence of improvements in both outcomes. Effect sizes ranged from small to large. There was some evidence that interventions were more effective with younger, non-clinical populations and where intervention teachers were experienced. Study quality was generally weak. 

**Conclusions**
There was no strong evidence base for positive effects of KCBM with children. However, the findings of the review are encouraging given the early stage of development of the field, and further research is warranted. Recommendations for future research include more robust methodological design, improved reporting, and a focus on developmental mechanisms of change.
AN  - WOS:000814924900001
AU  - Perkins,
AU  - N.
AU  - Sehmbi,
AU  - T.
AU  - Smith,
AU  - P.
DB  - Alerts 6_2022.enl
DO  - 10.1007/s12671-022-01925-4
L1  - internal-pdf://2783825179/Perkins-Effects of Kindness- and Compassion-Ba.pdf
PY  - 2022
SP  - 25
T2  - Mindfulness
TI  - Effects of Kindness- and Compassion-Based Meditation on Wellbeing, Prosociality, and Cognitive Functioning in Children and Adolescents: a Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000814924900001
UR  - https://link.springer.com/content/pdf/10.1007/s12671-022-01925-4.pdf
ER  -
TY  - JOUR
AB  - Camel milk is better tolerated than the milk of other ruminants, potentially expanding its consumer appeal. It also contains essential vitamins, minerals, and immunoglobulins, providing the milk with antioxidant, antibacterial, and antiviral properties. These properties may reduce oxidative stress in camel milk consumers, ameliorating many conditions, including those of the CNS, such as autism spectrum disorders (ASDs). 

We performed a meta-analysis of randomized controlled trials (RCTs) in which camel milk administration (boiled or raw) was examined as an ASD treatment intervention. The primary endpoint was participants&#039; total autism scores, determined using the Childhood Autistic Responsiveness Scale (CARS). A comparison of the responsiveness in these ASD intervention groups yielded a mean difference (MD) of 1.99 (0.89, 3.08) in those consuming boiled camel milk, MD = 2.77 (1.92, 3.61) in raw camel milk consumers, and MD = -1.02 (-0.10, 2.13) in cow milk consumers. Heterogeneity was notably low among the examined studies. Treatment of ASD with raw and boiled camel milk resulted in significantly lower CARS scores than the placebo.

 Our findings support the development of larger, more populated RCTs to establish camel milk&#039;s overall potential as a therapeutic intervention for CNS disorders.
AN  - 35669459
AU  - Kandeel,
AU  - M.
AU  - El-Deeb,
AU  - W.
DB  - Alerts 6_2022.enl
DO  - /10.1155/2022/6422208
L1  - internal-pdf://3539781736/Kandeel-2022-The Application of Natural Camel.pdf
PY  - 2022
SP  - 6422208
T2  - Bioinorganic Chemistry &amp; Applications
TI  - The Application of Natural Camel Milk Products to Treat Autism-Spectrum Disorders: Risk Assessment and Meta-Analysis of Randomized Clinical Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35669459
UR  - https://downloads.hindawi.com/journals/bca/2022/6422208.pdf
VL  - 2022
ER  -
TY  - JOUR
AB  - **Background:**
At-risk youth may be defined as a diverse group of young people in unstable life circumstances, who are currently experiencing or are at risk of developing one or more serious problems. At-risk youth are often very unlikely to seek out help for themselves within the established venues, as their adverse developmental trajectories have installed a lack of trust in authorities such as child protection agencies and social workers. To help this population, a number of outreach programmes have been established seeking to help the young people on an ad hoc basis, meaning that the interventions are designed to fit the individual needs of each young person rather than as a one-size-fits-all treatment model. The intervention in this review is targeted outreach work which may be (but does not have to be) multicomponent programmes in which outreach may be combined with other services.ObjectivesThe main objective of this review was to answer the following research questions: What are the effects of outreach programmes on problem/high-risk behaviour of young people between 8 and 25 years of age living in OECD countries? Are they less likely to experience an adverse outcome such as school failure or drop-out, runaway and homelessness, substance and/or alcohol abuse, unemployment, long-term poverty, delinquency and more serious criminal behaviour?

**Search Methods:**
We identified relevant studies through electronic searches of bibliographic databases, governmental and grey literature repositories, hand search in specific targeted journals, citation tracking, and Internet search engines. The database searches were carried out in September 2020 and other resources were searched in October and November 2021. We searched to identify both published and unpublished literature, and reference lists of included studies and relevant reviews were searched.

**Selection Criteria:**
The intervention was targeted outreach work which may have been combined with other services. Young people between 8 and 25 years of age living in OECD countries, who either have experienced or is at-risk of experiencing an adverse outcome were eligible. Our primary focus was on measures of problem/high-risk behaviour and a secondary focus was on social and emotional outcomes. All study designs that used a well-defined control group were eligible for inclusion. Studies that utilised qualitative approaches were not included.

**Data Collection and Analysis:**
The total number of potentially relevant studies constituted 17,659 hits. A total of 16 studies (17 different interventions) met the inclusion criteria. Only five studies could be used in the data synthesis. Eight studies could not be used in the data synthesis as they were judged to have critical risk of bias and, in accordance with the protocol, were excluded from the meta-analysis on the basis that they would be more likely to mislead than inform. Two studies (three interventions) did not provide enough information enabling us to calculate an effect size and standard error, and one study did not provide enough information to assess risk of bias. Meta-analysis of all outcomes were conducted on each conceptual outcome separately. All analyses were inverse variance weighted using random effects statistical models incorporating both the sampling variance and between study variance components into the study level weights. Random effects weighted mean effect sizes were calculated using 95% confidence intervals. Too few studies were included to carry out any sensitivity analyses.

**Main Results:**
Four of the five studies used for meta analysis were from the USA and one was from Canada. The timespan in which included studies were carried out was 32 years, from 1985 to 2017; on average the intervention year was 2005. The average number of participants in the analysed interventions was 116, ranging from 30 to 346 and the average number of controls was 81, ranging from 32 to 321. At most, the results from two studies could be pooled in a single meta‐analysis. It was only possible to pool the outcomes drug (other than marijuana) use, marijuana use and alcohol use each at two different time points (one and 3 months follow up). At 1 month follow up the weighted averages varied between zero and 0.05 and at 3 months follow up between &minus;0.17 and 0.07. None of them were statistically significant. In addition, a number of other outcomes were reported in a single study only.

**Authors&#039; Conclusions:**
 Overall, there were too few studies included in any of the meta‐analyses in order for us to draw any conclusion concerning the effectiveness of outreach. The vast majority of studies were undertaken in the USA. The dominance of the USA as the main country in which outreach interventions meeting our inclusion criteria have been evaluated using rigorous methods and within our specific parameters clearly limits the generalisability of the findings. None of the studies, however, was considered to be of overall high quality in our risk of bias assessment and the process of excluding studies with critical risk of bias from the meta‐analysis applied in this review left us with only five of a total of 16 possible studies to synthesise. Further, because too few studies reported results on the same type of outcome at most two studies could be combined in a particular meta‐analysis. Given the limited number of rigorous studies available from countries other than the USA, it would be natural to consider conducting a series of randomised controlled trials evaluating the effectiveness of outreach for at‐risk youth in countries outside the USA. The trial(s) should be designed, conducted and reported according to methodological criteria for rigour in respect of internal and external validity to achieve robust results and preferably reporting a larger number of outcomes.
AU  - Filges,
AU  - T.
AU  - Dalgaard,
AU  - N.
AU  - T.
AU  - Viinholt,
AU  - B.
AU  - C.
AU  - A
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/cl2.1282
L1  - internal-pdf://0177218656/Filges - Outreach programs to improve life cir.pdf
PY  - 2022
T2  - Campbell Systematic Reviews
TI  - Outreach programs to improve life circumstances and prevent further adverse developmental trajectories of at-risk youth in OECD countries: A systematic review
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis considered evidence of guided play compared to direct instruction or free play to support children&#039;s learning and development. 

Interventions from 39 studies were reviewed (published 1977-2020); 17 were included in meta-analysis (Ntotal = 3893; Mchildage = 1-8 years; Mgirls 49.8%; Methnicity White 41%, African American/Black 28%, Hispanic 19%). Guided play had a greater positive effect than direct instruction on early maths skills (g = 0.24), shape knowledge (g = 0.63), and task switching (g = 0.40); and than free play on spatial vocabulary (g = 0.93). 

Differences were not identified for other key outcomes. Narrative synthesis highlighted heterogeneity in the conceptualization and implementation of guided play across studies. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-23203-001
AU  - Skene,
AU  - K.
AU  - O&#039;Farrelly,
AU  - C.
AU  - M.
AU  - Byrne,
AU  - E.
AU  - M.
AU  - Kirby,
AU  - N.
AU  - Stevens,
AU  - E.
AU  - C.
AU  - Ramchandani,
AU  - P.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/cdev.13730
L1  - internal-pdf://0618964728/Can guidance during play enhance children-2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Child Development
TI  - Can guidance during play enhance children&#039;s learning and development in educational contexts? A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-23203-001
UR  - https://srcd.onlinelibrary.wiley.com/doi/10.1111/cdev.13730
ER  -
TY  - JOUR
AB  - Past meta-analyses in mental health interventions failed to use stringent inclusion criteria and diverse moderators, therefore, there is a need to employ more rigorous methods to provide evidence-based and updated results on this topic. This study presents an updated meta-analysis of interventions targeting anxiety or depression using more stringent inclusion criteria (e.g., baseline equivalence, no significant differential attrition) and additional moderators (e.g., sample size and program duration) than previous reviews. This meta-analysis includes 29 studies of 32 programs and 22,420 students (52% female, 79% White). Among these studies, 22 include anxiety outcomes and 24 include depression outcomes. Overall, school-based mental health interventions in grades K-12 are effective at reducing depression and anxiety (ES = 0.24, p = 0.002). Moderator analysis shows that improved outcomes for studies with anxiety outcomes, cognitive behavioral therapy, interventions delivered by clinicians, and secondary school populations. Selection modeling reveals significant publication and outcome selection bias. This meta-analysis suggests school-based mental health programs should strive to adopt cognitive behavioral therapy and deliver through clinicians at the secondary school level where possible.
AN  - 36229755
AU  - Zhang,
AU  - Q.
AU  - Wang,
AU  - J.
AU  - Neitzel,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10964-022-01684-4
L1  - internal-pdf://0178661807/Zhang-2022-School-based Mental Health Interven.pdf
PY  - 2022
SP  - 13
T2  - Journal of Youth &amp; Adolescence
TI  - School-based Mental Health Interventions Targeting Depression or Anxiety: A Meta-analysis of Rigorous Randomized Controlled Trials for School-aged Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36229755
UR  - https://link.springer.com/content/pdf/10.1007/s10964-022-01684-4.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - **BACKGROUND**
There is abundant evidence showing that iron deficiency is closely linked with delayed brain development, worse school performance, and behavioral abnormalities. However, evidence on the impact of iron supplementation among children and adolescents in low- and middle-income countries (LMICs) has been inconsistent. This study aims to examine the effect of oral iron supplementation on cognitive function among children and adolescents in LMICs.

**METHODS**
A systematic review and meta-analysis was conducted to examine the impact of iron supplementation on cognitive function (including intelligence, attention, short-term memory, long-term memory, and school performance) among children and adolescents aged 5 to 19. We searched PubMed, Embase, Web of Science, CINAHL, and references of related articles published from the inception of the databases to 1 May 2022. Random-effects pooled standardized mean difference (SMD) with 95% confidence intervals (CIs) were calculated to estimate the effect of iron supplementation on cognitive function. We also investigated the heterogeneity of the effects using subgroup and meta-regression analyses. This review was registered with PROSPERO (CRD42020179064).

**RESULTS**
Nine studies with 1196 individual participants from five countries were identified and included. Iron had a positive impact on intelligence test scores among children and adolescents (SMD = 0.47, 95% confidence interval [CI]: 0.10, 0.83). Meta-regression showed that the intelligence test scores improved with increasing the iron supplement dose (odds ratio [CI] = 1.02, 95% CI: 1.00, 1.04). There were no significant effects on attention, short-term memory, long-term memory, or school performance.

**CONCLUSIONS**
Oral iron intake can improve the intelligence test scores of children and adolescents in LMICs and should be considered for future nutritional interventions.
AD  - Chen, Zekun. Vanke School of Public Health, Tsinghua University, Beijing 100084, China.Yang, Huanhuan. Vanke School of Public Health, Tsinghua University, Beijing 100084, China.Wang, Dongqing. Department of Global Health and Population, Department of Nutrition, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA.Sudfeld, Christopher R. Department of Global Health and Population, Department of Nutrition, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA.Zhao, Ai. Vanke School of Public Health, Tsinghua University, Beijing 100084, China.Xin, Yiqian. Duke Global Health Institute, Duke University, Durham, NC 27705, USA.Chen, Jiawen Carmen. Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.Fawzi, Wafaie W. Department of Global Health and Population, Department of Nutrition, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA.Xing, Yan. Department of Pediatrics, Peking University Third Hospital, Beijing 100191, China.Li, Zhihui. Vanke School of Public Health, Tsinghua University, Beijing 100084, China.
AN  - 36558491
AU  - Chen,
AU  - Z.
AU  - Yang,
AU  - H.
AU  - Wang,
AU  - D.
AU  - Sudfeld,
AU  - C.
AU  - R.
AU  - Zhao,
AU  - A.
AU  - Xin,
AU  - Y.
AU  - Chen,
AU  - J.
AU  - C.
AU  - Fawzi,
AU  - W.
AU  - W.
AU  - Xing,
AU  - Y.
AU  - Li,
AU  - Z.
DA  - Dec 15
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/nu14245332
DP  - Ovid Technologies
J2  - Nutrients
KW  - Humans
KW  - Child
KW  - Adolescent
KW  - *Iron
KW  - *Developing Countries
KW  - Cognition
KW  - Attention
KW  - Dietary Supplements
KW  - E1UOL152H7 (Iron)
L1  - internal-pdf://0827674517/Chen-2022-Effect of Oral Iron Supplementation.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Using Smart Source ParsingDecChen, ZekunYang, HuanhuanWang, DongqingSudfeld, Christopher RZhao, AiXin, YiqianChen, Jiawen CarmenFawzi, Wafaie WXing, YanLi, Zhihui5332
PY  - 2022
SP  - 15
T2  - Nutrients
TI  - Effect of Oral Iron Supplementation on Cognitive Function among Children and Adolescents in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=36558491
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36558491&amp;id=doi:10.3390%2Fnu14245332&amp;issn=2072-6643&amp;isbn=&amp;volume=14&amp;issue=24&amp;spage=&amp;pages=&amp;date=2022&amp;title=Nutrients&amp;atitle=Effect+of+Oral+Iron+Supplementation+on+Cognitive+Function+among+Children+and+Adolescents+in+Low-+and+Middle-Income+Countries%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Chen&amp;pid=%3Cauthor%3EChen+Z%3C%2Fauthor%3E%3CAN%3E36558491%3C%2FAN%3E%3CDT%3EMeta-Analysis%3C%2FDT%3E
UR  - https://mdpi-res.com/d_attachment/nutrients/nutrients-14-05332/article_deploy/nutrients-14-05332-v2.pdf?version=1671175351
VL  - 14
ER  -
TY  - JOUR
AB  - **Background**
One person in every four will suffer from a diagnosable mental health condition during their life. Such conditions can have a devastating impact on the lives of the individual and their family, as well as society. International healthcare policy makers have increasingly advocated and enshrined partnership models of mental health care. Shared decision‐making (SDM) is one such partnership approach. Shared decision‐making is a form of service user‐provider communication where both parties are acknowledged to bring expertise to the process and work in partnership to make a decision. This review assesses whether SDM interventions improve a range of outcomes. This is the first update of this Cochrane Review, first published in 2010.

**Objectives**
To assess the effects of SDM interventions for people of all ages with mental health conditions, directed at people with mental health conditions, carers, or healthcare professionals, on a range of outcomes including: clinical outcomes, participation/involvement in decision‐making process (observations on the process of SDM; user‐reported, SDM‐specific outcomes of encounters), recovery, satisfaction, knowledge, treatment/medication continuation, health service outcomes, and adverse outcomes.

**Search methods**
We ran searches in January 2020 in CENTRAL, MEDLINE, Embase, and PsycINFO (2009 to January 2020). We also searched trial registers and the bibliographies of relevant papers, and contacted authors of included studies. We updated the searches in February 2022. When we identified studies as potentially relevant, we labelled these as studies awaiting classification.

**Selection criteria**
Randomised controlled trials (RCTs), including cluster‐randomised controlled trials, of SDM interventions in people with mental health conditions (by Diagnostic and Statistical Manual of Mental Disorders (DSM) or International Classification of Diseases (ICD) criteria).

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane. Two review authors independently screened citations for inclusion, extracted data, and assessed risk of bias. We used GRADE to assess the certainty of the evidence.

**Main results**
This updated review included 13 new studies, for a total of 15 RCTs. Most participants were adults with severe mental illnesses such as schizophrenia, depression, and bipolar disorder, in higher‐income countries. None of the studies included children or adolescents. 

Primary outcomes
We are uncertain whether SDM interventions improve clinical outcomes, such as psychiatric symptoms, depression, anxiety, and readmission, compared with control due to very low‐certainty evidence.

For readmission, we conducted subgroup analysis between studies that used usual care and those that used cognitive training in the control group. There were no subgroup differences.

Regarding participation (by the person with the mental health condition) or level of involvement in the decision‐making process, we are uncertain if SDM interventions improve observations on the process of SDM compared with no intervention due to very low‐certainty evidence. On the other hand, SDM interventions may improve SDM‐specific user‐reported outcomes from encounters immediately after intervention compared with no intervention (standardised mean difference (SMD) 0.63, 95% confidence interval (CI) 0.26 to 1.01; 3 studies, 534 participants; low‐certainty evidence). However, there was insufficient evidence for sustained participation or involvement in the decision‐making processes.

Secondary outcomes
We are uncertain whether SDM interventions improve recovery compared with no intervention due to very low‐certainty evidence.

We are uncertain if SDM interventions improve users&#039; overall satisfaction. However, one study (241 participants) showed that SDM interventions probably improve some aspects of users&#039; satisfaction with received information compared with no intervention: information given was rated as helpful (risk ratio (RR) 1.33, 95% CI 1.08 to 1.65); participants expressed a strong desire to receive information this way for other treatment decisions (RR 1.35, 95% CI 1.08 to 1.68); and strongly recommended the information be shared with others in this way (RR 1.32, 95% CI 1.11 to 1.58). The evidence was of moderate certainty for these outcomes. However, this same study reported there may be little or no effect on amount or clarity of information, while another small study reported there may be little or no change in carer satisfaction with the SDM intervention. The effects of healthcare professional satisfaction were mixed: SDM interventions may have little or no effect on healthcare professional satisfaction when measured continuously, but probably improve healthcare professional satisfaction when assessed categorically.

We are uncertain whether SDM interventions improve knowledge, treatment continuation assessed through clinic visits, medication continuation, carer participation, and the relationship between users and healthcare professionals because of very low‐certainty evidence.

Regarding length of consultation, SDM interventions probably have little or no effect compared with no intervention (SDM 0.09, 95% CI ‐0.24 to 0.41; 2 studies, 282 participants; moderate‐certainty evidence). On the other hand, we are uncertain whether SDM interventions improve length of hospital stay due to very low‐certainty evidence.

There were no adverse effects on health outcomes and no other adverse events reported.

Authors&#039; conclusions
This review update suggests that people exposed to SDM interventions may perceive greater levels of involvement immediately after an encounter compared with those in control groups. Moreover, SDM interventions probably have little or no effect on the length of consultations. 

Overall we found that most evidence was of low or very low certainty, meaning there is a generally low level of certainty about the effects of SDM interventions based on the studies assembled thus far. There is a need for further research in this area.
AU  - Aoki
AU  - Y,
AU  - Yaju
AU  - Y,
AU  - Utsumi
AU  - T,
AU  - Sanyaolu
AU  - L,
AU  - Storm
AU  - M,
AU  - Takaesu
AU  - Y,
AU  - Watanabe
AU  - K,
AU  - Watanabe
AU  - N,
AU  - Duncan
AU  - E,
AU  - Edwards
AU  - AGK.
DB  - Alerts 6_2022.enl
DO  - /10.1002/14651858.CD007297.pub3
L1  - internal-pdf://4216437225/Aoki_et_al-2022-Cochrane_Database_of_Systemati.pdf
PY  - 2022
T2  - Cochrane Database of Systematic Reviews
TI  - Shared decision-making interventions for people with mental health conditions
ER  -
TY  - JOUR
AB  - Globally, an estimated 79.5 million individuals have been displaced, nearly 40% of whom are children. Parenting interventions may have the potential to improve outcomes for displaced families. 

To investigate this, we conducted a systematic review to identify the types of caregiver or parenting interventions that have been evaluated among displaced families, to assess their efficacy across a range of contexts, and to describe their cultural and contextual adaptations. The review followed PRISMA guidelines. 

At stage one, all articles describing caregiver/parenting interventions for forcibly displaced families were included to provide a scoping review of the state of the literature. At stage two, only randomized controlled trials (RCTs) and quasi-experimental designs were included, allowing for quantitative analysis of program effects. 

A total of 30 articles (24 studies) were identified in stage one. 95.8% of these articles were published in the past 10 years. Of these, 14 articles (10 studies) used an RCT or quasi-experimental design to assess program efficacy or effectiveness. Relative to control groups, those assigned to caregiving programs showed significant, beneficial effects across the domains of parenting behaviors and attitudes, child psychosocial and developmental outcomes, and parent mental health. Cultural adaptations and recruitment and engagement strategies are described. 

The evidence base for caregiving programs for displaced families has expanded in recent years but remains limited. Caregiving/parenting programs show promise for reducing the negative effects of forced displacement on families, but future studies are needed to understand which programs show the greatest potential for scalability. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-22202-001
AU  - Gillespie,
AU  - S.
AU  - Banegas,
AU  - J.
AU  - Maxwell,
AU  - J.
AU  - Chan,
AU  - A.
AU  - C.
AU  - Darawshy,
AU  - N.
AU  - A.-S.
AU  - Wasil,
AU  - A.
AU  - R.
AU  - Marsalis,
AU  - S.
AU  - Gewirtz,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-021-00375-z
L1  - internal-pdf://2899679205/Parenting interventions for refugees and-2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Clinical Child and Family Psychology Review
TI  - Parenting interventions for refugees and forcibly displaced families: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-22202-001
UR  - https://link.springer.com/content/pdf/10.1007/s10567-021-00375-z.pdf
ER  -
TY  - JOUR
AB  - **Background:** 
Virtual reality (VR) is used as a distraction measure during painful clinical procedures associated with the use of needles. These procedures include vaccinations, blood draws, or the administration of medications, which can cause children to feel increased levels of pain and fear. 

**Objective:** 
The objective of this study was to collect and analyze the current evidence regarding the effectiveness of VR as a tool to distract children from pain and fear during needle procedures as compared to that of standard techniques. 

**Methods:** 
A systematic review and meta-analysis was performed. We included randomized clinical trials (RCTs) or quasi-RCTs with participants younger than 21 years who underwent needle procedures in which the main distraction measure used was VR and where the main outcome measure was pain. The databases searched included the PubMed, Web of Science, Scopus, PsycINFO, CINAHL, and Cochrane libraries. In this systematic review, the studies were analyzed by applying the Critical Appraisal Skills Program guide in Spanish and the Jadad scale. In the meta-analysis, the effect size of the studies was analyzed based on the results for pain and fear in children. 

**Results:** 
From 665 unique search results, 21 studies were included in this systematic review, most of which reported low methodological quality. The study sample cohorts ranged from a minimum of 15 participants to a maximum of 220 participants. Ten studies were included in the meta-analysis. The global effect of using VR as a distraction measure was a significant reduction in pain (inverse variance [IV] -2.37, 95% CI -3.20 to -1.54; Z=5.58; P&lt;.001) and fear (IV -1.26, 95% CI -1.89 to -0.63; Z=3.92; P&lt;.001) in children in the experimental groups. 

**Conclusions:** 
The quality of the studies was mostly low. The main limitations were the impossibility of blinding the participants and health care personnel to the VR intervention. Nonetheless, the use of VR as a distraction measure was effective in reducing pain and fear in children during procedures involving needles.
AN  - WOS:000886937900012
AU  - Lluesma-Vidal,
AU  - M.
AU  - Gonzalez,
AU  - R.
AU  - Garcia-Garces,
AU  - L.
AU  - Sanchez-Lopez,
AU  - M.
AU  - I.
AU  - Peyro,
AU  - L.
AU  - Ruiz-Zaldibar,
AU  - C.
DB  - Alerts 6_2022.enl
DO  - 10.2196/35008
L1  - internal-pdf://3645624602/Lluesma_Vidal_2022.pdf
PY  - 2022
SP  - 12
T2  - Jmir Serious Games
TI  - Effect of Virtual Reality on Pediatric Pain and Fear During Procedures Involving Needles: Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000886937900012
VL  - 10
ER  -
TY  - JOUR
AB  - Sandplay therapy is a cross-cultural, psychodynamic, nondirective, multisensory psychotherapy method founded by Dora Kalff. Sandplay is used with children and adults with a range of mental health problems. Despite sandplay&#039;s growing popularity, its empirical evidence base is less developed than more well-known therapies. This international study provides a meta-analysis of the available quantitative outcome studies in order to summarize the growing evidence base of sandplay. The meta-analysis specifically examined emotional and behavioral outcome measures of treatment with sandplay therapy. The initial search identified 1,715 potential records from over 16 countries. After screening, 40 studies from eight countries representing 1,284 participants met the inclusion criteria. Mean effect sizes were calculated using a random effects model with the Comprehensive Meta-Analysis (CMA) program. The overall effect size was large (Hedges&#039; g = 1.10). Large effect sizes were maintained for internalizing, externalizing, and attention-deficit/hyperactivity disorder (ADHD) symptoms. Improved effect sizes were associated with individual treatment over the group format. These results suggest that sandplay therapy is an effective treatment method for children and adults with a wide variety of mental health concerns. Limitations and suggestions for further research are discussed. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-48948-001
AU  - Wiersma,
AU  - J.
AU  - K.
AU  - Freedle,
AU  - L.
AU  - R.
AU  - McRoberts,
AU  - R.
AU  - Solberg,
AU  - K.
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/pla0000180
L1  - internal-pdf://1992124277/A meta-analysis of sandplay therapy treat-2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - International Journal of Play Therapy
TI  - A meta-analysis of sandplay therapy treatment outcomes
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-48948-001
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
The efficacy of different forms of acupuncture for the treatment of nocturnal enuresis in children is not known. 

**OBJECTIVE**
To determine the efficacy of different forms of acupuncture, such as manual acupuncture, laser/electroacupuncture, acupoint injection, and moxibustion, for the treatment of nocturnal enuresis. 

**METHODS**
A literature search was conducted on Medline, EMBASE, Web of Science, CINAHL, PubMed, Physiotherapy Evidence Database, and Scopus from database inception to September 2020. The Cochrane risk of bias tool was utilised to evaluate the risk of bias in each included study. The quality of the evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation tool. 

**RESULTS**
Thirteen trials (n = 890) were included. Meta-analyses revealed significantly greater numbers of children reporting improved nocturnal enuresis in the moxibustion (p = 0.004), acupoint injection (p = 0.020), and laser acupuncture (p = 0.001) groups than in the control groups. Meta-analyses showed no significant differences in the numbers of children reporting the complete cure of nocturnal enuresis between laser acupuncture and desmopressin (p = 0.57). 

**CONCLUSIONS**
 The review identified moxibustion, acupoint injections, and laser acupuncture as effective treatments for nocturnal enuresis in children. However, the evidence for these interventions is limited and of very-low-grade quality. The effects of laser acupuncture compared with desmopressin remain inconclusive.
AN  - 34893441
AU  - Kannan,
AU  - P.
AU  - Bello,
AU  - U.
AU  - M.
DB  - Alerts 6_2022.enl
DO  - /10.1016/j.explore.2021.11.008
L1  - internal-pdf://1763756245/1-s2.0-S1550830721002433-main.cleaned.pdf
PY  - 2022
SP  - 488-497
T2  - Explore: The Journal of Science &amp; Healing
TI  - The efficacy of different forms of acupuncture for the treatment of nocturnal enuresis in children: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34893441
UR  - https://www.sciencedirect.com/science/article/pii/S1550830721002433?via%3Dihub
VL  - 18
ER  -
TY  - JOUR
AB  - **Background** 
Specific programs are often implemented for specific child mental health problems, while many children suffer from comorbid problems. Ideally, programs reduce a wider range of mental health problems. The present study tested whether parenting programs for children&#039;s conduct problems, and which individual and clusters of program elements, have additional effects on children&#039;s emotional problems. 

**Methods** 
We updated the search of a previous systematic review in 11 databases (e.g., PsycINFO and MEDLINE) and included studies published until July 2020 with keywords relating to &#039;parenting&#039;, &#039;program&#039;, and &#039;child behavioral problems&#039;. Also, we searched for recent trials in four trial registries and contacted protocol authors. Studies were eligible for inclusion if they used a randomized controlled trial to evaluate the effects of a parenting program for children aged 2-10 years which was based on social learning theory and included a measure of children&#039;s emotional problems postintervention. 

**Results** 
We identified 69 eligible trials (159 effect sizes; 6,240 families). Robust variance estimation showed that parenting programs had small significant parent-reported additional effects on emotional problems immediately postintervention (Cohen&#039;s d = -0.14; 95% CI, -0.21, -0.07), but these effects faded over time. Teachers and children did not report significant effects. Additional effects on emotional problems were larger in samples with clinical baseline levels of such problems. No individual program elements predicted larger additional effects. Of the clusters of elements, combining behavior management and relationship enhancement elements was most likely to yield the strongest additional effects. 

**Conclusions** 
The additional effects on emotional problems of parenting programs designed to reduce conduct problems are limited, but some clusters of elements predict larger effects. Our findings may contribute to realistic expectations of the benefits of parenting programs for children&#039;s conduct problems and inform the development of programs with wider benefits across mental health problems. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2023-02152-001
AU  - Kjobli,
AU  - J.
AU  - Melendez-Torres,
AU  - G.
AU  - Gardner,
AU  - F.
AU  - Backhaus,
AU  - S.
AU  - Linnerud,
AU  - S.
AU  - Leijten,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13697
L1  - internal-pdf://3030237999/Kjobli-2022-Research review_ Effects of parent.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Journal of Child Psychology and Psychiatry
TI  - Research review: Effects of parenting programs for children&#039;s conduct problems on children&#039;s emotional problems - a network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc19&amp;AN=2023-02152-001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.13697?download=true
ER  -
TY  - JOUR
AB  - **Background**
Primary healthcare, particularly Indigenous‐led services, are well placed to deliver services that reflect the needs of Indigenous children and their families. Important characteristics identified by families for primary health care include services that support families, accommodate sociocultural needs, recognise extended family child‐rearing practices, and Indigenous ways of knowing and doing business. Indigenous family‐centred care interventions have been developed and implemented within primary healthcare services to plan, implement, and support the care of children, immediate and extended family and the home environment. The delivery of family‐centred interventions can be through environmental, communication, educational, counselling, and family support approaches.

**Objectives**
To evaluate the benefits and harms of family‐centred interventions delivered by primary healthcare services in Canada, Australia, New Zealand, and the USA on a range of physical, psychosocial, and behavioural outcomes of Indigenous children (aged from conception to less than five years), parents, and families.Search methodsWe used standard, extensive Cochrane search methods. The latest search date was 22 September 2021.Selection criteriaWe included randomised controlled trials (RCTs), cluster RCTs, quasi‐RCTs, controlled before‐after studies, and interrupted time series of family‐centred care interventions that included Indigenous children aged less than five years from Canada, Australia, New Zealand, and the USA. Interventions were included if they met the assessment criteria for family‐centred interventions and were delivered in primary health care. Comparison interventions could include usual maternal and child health care or one form of family‐centred intervention versus another.

**Data collection and analysis**
We used standard Cochrane methods. Our primary outcomes were 1. overall health and well‐being, 2. psychological health and emotional behaviour of children, 3. physical health and developmental health outcomes of children, 4. family health‐enhancing lifestyle or behaviour outcomes, 5. psychological health of parent/carer. 6. adverse events or harms. Our secondary outcomes were 7. parenting knowledge and awareness, 8. family evaluation of care, 9. service access and utilisation, 10. family‐centredness of consultation processes, and 11. economic costs and outcomes associated with the interventions. We used GRADE to assess the certainty of the evidence for our primary outcomes.Main resultsWe included nine RCTs and two cluster‐RCTs that investigated the effect of family‐centred care interventions delivered by primary healthcare services for Indigenous early child well‐being. There were 1270 mother&ndash;child dyads and 1924 children aged less than five years recruited. Seven studies were from the USA, two from New Zealand, one from Canada, and one delivered in both Australia and New Zealand. The focus of interventions varied and included three studies focused on early childhood caries; three on childhood obesity; two on child behavioural problems; and one each on negative parenting patterns, child acute respiratory illness, and sudden unexpected death in infancy. Family‐centred education was the most common type of intervention delivered. Three studies compared family‐centred care to usual care and seven studies provided some &#039;minimal&#039; intervention to families such as education in the form of pamphlets or newsletters. One study provided a minimal intervention during the child&#039;s first 24 months and then the family‐centred care intervention for one year. No studies had low or unclear risk of bias across all domains. All studies had a high risk of bias for the blinding of participants and personnel domain.

Family‐centred care may improve overall health and well‐being of Indigenous children and their families, but the evidence was very uncertain. The pooled effect estimate from 11 studies suggests that family‐centred care improved the overall health and well‐being of Indigenous children and their families compared no family‐centred care (standardised mean difference (SMD) 0.14, 95% confidence interval (CI) 0.03 to 0.24; 2386 participants).We are very uncertain whether family‐centred care compared to no family‐centred care improves the psychological health and emotional behaviour of children as measured by the Infant Toddler Social Emotional Assessment (ITSEA) (Competence domain) (mean difference (MD) 0.04, 95% CI
AU  - Strobel,
AU  - N.
AU  - Chamberlain,
AU  - C.
AU  - Campbell,
AU  - S.
AU  - K.
AU  - Shields,
AU  - L.
AU  - Bainbridge,
AU  - R.
AU  - G.
AU  - Adams,
AU  - C.
AU  - Edmond,
AU  - K.
AU  - M.
AU  - Marriott,
AU  - R.
AU  - McCalman,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD012463.pub2
L1  - internal-pdf://3084239092/Strobel_et_al-2022-Cochrane_Database_of_System.pdf
PY  - 2022
T2  - Cochrane Database of Systematic Reviews
TI  - Family‐centred interventions for Indigenous early childhood well‐being by primary healthcare services
ER  -
TY  - JOUR
AB  - We conducted the first systematic review and series of meta-analyses to assess the efficacy and tolerability of melatonin in children/adolescents or adults with sleep or mental health disorders, using the same set of criteria across disorders and ages. 

Based on a pre-registered protocol (PROPSPERO: CRD42021289827), we searched a broad range of electronic databases up to 02.02.2021 for randomized control trials (RCTs) of melatonin. We assessed study quality using the Risk of Bias tool, v2. 

We included a total of 34 RCTs (21 in children/adolescents: N = 984; 13 in adults: N = 1014). We found evidence that melatonin significantly improved sleep onset latency and total sleep time, but not sleep awaking, in children and adolescents with a variety of neurodevelopmental disorders, and sleep onset latency (measured by diary) as well as total sleep time (measured with polysomnography) in adults with delayed sleep phase disorder. No evidence of significant differences between melatonin and placebo was found in terms of tolerability. 

We discuss clinical and research implications of our findings. Copyright &copy; 2022 The Authors
AN  - 2018889737
AU  - Salanitro,
AU  - M.
AU  - Wrigley,
AU  - T.
AU  - Ghabra,
AU  - H.
AU  - de
AU  - Haan,
AU  - E.
AU  - Hill,
AU  - C.
AU  - M.
AU  - Solmi,
AU  - M.
AU  - Cortese,
AU  - S.
DB  - Alerts 6_2022.enl
DO  - /10.1016/j.neubiorev.2022.104723
L1  - internal-pdf://3742093165/1-s2.0-S0149763422002123-main.cleaned.pdf
PY  - 2022
T2  - Neuroscience and Biobehavioral Reviews
TI  - Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis
UR  - https://www.elsevier.com/locate/neubiorev
UR  - https://www.sciencedirect.com/science/article/pii/S0149763422002123?via%3Dihub
VL  - 139 (no pagination)
ER  -
TY  - JOUR
AB  - Children with autism spectrum disorder (ASD) present with persistent deficits in both social communication and interactions, along with the presence of restricted and repetitive behaviors, resulting in significant impairment in significant areas of functioning. Children with ASD consistently reported significantly lower vitamin D levels than typically developing children. Moreover, vitamin D deficiency was found to be strongly correlated with ASD severity. Theoretically, vitamin D can affect neurodevelopment in children with ASD through its anti-inflammatory properties, stimulating the production of neurotrophins, decreasing the risk of seizures, and regulating glutathione and serotonin levels.

 A Title/Abstract specific search for publications on Vitamin D supplementation trials up to June 2021 was performed using two databases: PubMed and Cochrane Library. 

Twelve experimental studies were included in the synthesis of this review. 

Children with ASD reported a high prevalence of vitamin D deficiency or insufficiency. In general, it was observed that improved vitamin D status significantly reduced the ASD severity, however, this effect was not consistently different between the treatment and control groups. The variations in vitamin D dose protocols and the presence of concurrent interventions might provide an explanation for the variability of results. The age of the child for introducing vitamin D intervention was identified as a possible factor determining the effectiveness of the treatment. Common limitations included a small number of participants and a short duration of follow-ups in the selected studies. Long-term, well-designed randomized controlled trials are warranted to confirm the effect of vitamin D on severity in children with ASD. Copyright &copy; 2021 by the authors. Licensee MDPI, Basel, Switzerland.
AN  - 2015017037
AU  - Kittana,
AU  - M.
AU  - Ahmadani,
AU  - A.
AU  - Stojanovska,
AU  - L.
AU  - Attlee,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/nu14010026
L1  - internal-pdf://0476552391/The role of vitamin d supplementation in-2022.pdf
PY  - 2022
T2  - Nutrients
TI  - The role of vitamin d supplementation in children with autism spectrum disorder: A narrative review
UR  - https://www.mdpi.com/2072-6643/14/1/26/pdf
UR  - https://mdpi-res.com/d_attachment/nutrients/nutrients-14-00026/article_deploy/nutrients-14-00026-v2.pdf
VL  - 14(1) (no pagination)
ER  -
TY  - JOUR
AB  - OBJECTIVE: 
Utilizing a multi-level meta-analytic approach, this review is the first to systematically quantify the efficacy of reading interventions for school-aged children with ADHD and identify potential factors that may increase the success of reading-related interventions for these children. 

METHOD: 
18 studies (15 peer-reviewed articles, 3 dissertations) published from 1986 to 2020 (N = 564) were meta-analyzed. 

RESULTS: 
Findings revealed reading interventions are highly effective for improving reading skills based on both study-developed/curriculum-based measures (g = 1.91) and standardized/norm-referenced achievement tests (g = 1.11) in high-quality studies of children with rigorously-diagnosed ADHD. Reading interventions that include at least 30 hours of intervention targeting decoding/phonemic awareness meet all benchmarks to be considered a Level 1 (Well-Established) Evidence-Based Practice with Strong Research Support for children with ADHD based on clinical and special education criteria. 

CONCLUSIONS: 
Our findings collectively indicate that reading interventions should be the first-line treatment for reading difficulties among at-risk readers with ADHD.
AN  - 36278436
AU  - Chan,
AU  - E.
AU  - S.
AU  - M.
AU  - Shero,
AU  - J.
AU  - A.
AU  - Hand,
AU  - E.
AU  - D.
AU  - Cole,
AU  - A.
AU  - M.
AU  - Gaye,
AU  - F.
AU  - Spiegel,
AU  - J.
AU  - A.
AU  - Kofler,
AU  - M.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/10870547221130111
L1  - internal-pdf://0429072410/10870547221130111.cleaned.pdf
PY  - 2022
SP  - 10870547221130111
T2  - Journal of Attention Disorders
TI  - Are Reading Interventions Effective for At-Risk Readers with ADHD? A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36278436
ER  -
TY  - JOUR
AB  - Objectives: 
To assess the effects of trauma-focused cognitive behavioral therapy (TF-CBT) among maltreated children, and to examine the role of potential moderators. 

Methods: 
A search of eight databases was conducted. Eighteen studies involving 11 randomized and quasi-randomized controlled trials with 965 maltreated children were included, and the effect sizes were pooled using random-effect models. 

Results:
There were large effect sizes for posttraumatic growth and emotional management. Moderate to large effects were evident for PTSD and depression, while small effects were found for anxiety, internalizing behavior, sexualized behavior, and parenting practice. Effects were maintained at 3-12 months for some outcome domains. The effectiveness of TF-CBT was better when delivered to older children, and versions of TF-CBT, delivery format, sessions, and treatment length will not affect effectiveness. 

Conclusions: 
TF-CBT effectively reduces abuse-related symptoms and improves positive psychosocial outcomes among maltreated children.
AN  - WOS:000905596200001
AU  - Wang,
AU  - W.
AU  - W.
AU  - Chen,
AU  - K.
AU  - Y.
AU  - Zhang,
AU  - H.
AU  - P.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1177/10497315221147277
L1  - internal-pdf://3838573837/10497315221147277.cleaned.pdf
PY  - 2022
SP  - 16
T2  - Research on Social Work Practice
TI  - Effectiveness of Trauma-Focused Cognitive Behavioral Therapy Among Maltreated Children: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000905596200001
ER  -
TY  - JOUR
AB  - **Objectives**
The aim of this study was to systematically review the literature investigating the acute effects of moderate-to-vigorous physical activity (MVPA) on executive functions (EFs) in children with attention-deficit/ hyperactivity disorder (ADHD) and perform a meta-analysis of the effects of MVPA on task components that require lower and higher EF demand in this population. 

**Methods**
The systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Six electronic databases, i.e., PubMed, Scopus, Web of Science, Embase, SPORTDiscus, and Education Resources Information Center (ERIC), were searched for eligible studies. Randomeffects weights were used to pool the effect sizes. Publication bias was assessed by Egger&#039;s regression test and Rosenthal&#039;s fail-safe N. This study is registered on PROSPERO, number CRD42020184082. 

**Results**
The electronic database search yielded 12 studies, which met the inclusion criteria, comprising a total of 375 participants. Eleven studies with data from 275 participants were included in the meta-analysis to examine the acute effects of MVPA on tasks with lower and higher EF demand. A single bout of MVPA had a small positive effect on tasks with lower (n = 10, g = 0.32, 95% CI = 0.123-0.517) and higher (n = 10, g = 0.25, 95% CI = 0.13-0.371) EF demand. No publication bias was found. Conclusions: A single bout of MVPA may have a general facilitative effect on cognition, indicating that acute MVPA may be a transient nonpharmacological adjunctive treatment for childhood ADHD.
AN  - WOS:000719891200003
AU  - Chueh,
AU  - T.
AU  - Y.
AU  - Hsieh,
AU  - S.
AU  - S.
AU  - Tsai,
AU  - Y.
AU  - J.
AU  - Yu,
AU  - C.
AU  - L.
AU  - Hung,
AU  - C.
AU  - L.
AU  - Benzing,
AU  - V.
AU  - Schmidt,
AU  - M.
AU  - Chang,
AU  - Y.
AU  - K.
AU  - Hillman,
AU  - C.
AU  - H.
AU  - Hung,
AU  - T.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.psychsport.2021.102097
L1  - internal-pdf://2755072614/1-s2.0-S1469029221002156-main.cleaned.pdf
PY  - 2022
SP  - 9
T2  - Psychology of Sport and Exercise
TI  - Effects of a single bout of moderate-to-vigorous physical activity on executive functions in children with attention-deficit/hyperactivity disorder: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000719891200003
VL  - 58
ER  -
TY  - JOUR
AB  - **Objective:**

Physical activity (PA) has been proposed as an adjunct treatment and secondary prevention interovention for attention-deficit hyperactivity/impulsivity disorder (ADHD) and oppositional defiant disorder (ODD). However, meta-analyses testing effects on symptoms and functional impairment have yielded conflicting results. 

**Methods:**
A systematic search of eight databases yielded 15 randomized controlled trial and 2 quasi-experimental design studies-including N = 881 youth (M = 9.75 years, 71% male)-that tested the effects of multi-week PA programs on symptoms and impairment of children with [or at-risk for] ADHD and/or ODD. 

**Results:**
Random effects meta-analyses favored PA groups on omnibus ADHD measures (g = 0.42, 95%CI[-0.62;-0.21]), combined ADHD symptoms (g = 0.50, 95%CI[-0.82;-0.17]), inattention (g = 0.41,95%CI[-0.82; 0.00]), and hyperactivity/impulsivity (g = 0.30, 95%CI[-0.56;-0.04]). Heterogeneity was moderate across studies (I2 = 49%, 95%CI[12%-to-70%]). Significant differences favored PA programs whether inclusion required diagnosis, programs augmented frontline treatments, and active or passive comparison groups were utilized. 

**Conclusion:**
Diverse PA programs can reduce ADHD symptoms, especially where they intentionally pursue this end.
AN  - WOS:001006183700004
AU  - Bustamante,
AU  - E.
AU  - E.
AU  - Balbim,
AU  - G.
AU  - M.
AU  - Ramer,
AU  - J.
AU  - D.
AU  - Santiago-Rodriguez,
AU  - M.
AU  - E.
AU  - DuBois,
AU  - D.
AU  - L.
AU  - Brunskill,
AU  - A.
AU  - Mehta,
AU  - T.
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1016/j.psychsport.2022.102268
L1  - internal-pdf://0208539211/Bustamante_2023.pdf
PY  - 2022
SP  - 11
T2  - Psychology of Sport and Exercise
TI  - Diverse multi-week physical activity programs reduce ADHD symptoms: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:001006183700004
UR  - https://www.sciencedirect.com/science/article/pii/S1469029222001364?via%3Dihub
VL  - 63
ER  -
TY  - JOUR
AB  - Non-suicidal self-injury (NSSI) in children and adolescents is a frequent phenomenon. NSSI at any time is a significant predictor of future NSSI but also, and more importantly, for suicide attempts. Less evidence is available for the impact, or more specifically, the therapeutic effect of psychotropic drugs on the emergence of NSSI in this population. The phenomenon is clinically highly relevant since adolescent psychiatric inpatients are often affected by NSSI and most of them are treated with psychotropic drugs. While previous reviews on NSSI comprised suicidal self-injury (SSI), this review aims at elucidating the potential impact of psychotropic drugs on the emergence of specifically NSSI in children and adolescents. Systematic searches of articles indexed electronically in PubMed, Embase and PsycInfo were conducted (PROSPERO CRD42020209505). Studies included in the quantitative synthesis were evaluated using the SIGN level of evidence rating. Meta-analyses were performed using RevMan (Version 5.4). 2227 records were identified through database searches. Two additional records were identified manually. In total, seven studies were included in qualitative and four studies in quantitative analyses. In a meta-analysis, selective serotonin reuptake inhibitors (SSRIs) were compared vs. control medication (placebo or serotonin-norepinephrine reuptake inhibitor) and here, no statistically significant difference between the groups could be observed regarding the frequency of NSSI events (Risk Ratio (RR) = 1.07, 95% confidence interval (CI) 0.60-1.91, p = 0.82, I2 = 12%). Evidence regarding the association of SSRI use and NSSI among children and adolescents is sparse and the impact of psychotropic drugs in general on NSSI rates in this population should be addressed in future clinical and observational studies. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-34788-001
AU  - Eggart,
AU  - V.
AU  - Cordier,
AU  - S.
AU  - Hasan,
AU  - A.
AU  - Wagner,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00406-022-01385-w
L1  - internal-pdf://0631895488/Psychotropic drugs for the treatment of n-2022.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - European Archives of Psychiatry and Clinical Neuroscience
TI  - Psychotropic drugs for the treatment of non-suicidal self-injury in children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-34788-001
UR  - https://link.springer.com/content/pdf/10.1007/s00406-022-01385-w.pdf
ER  -
TY  - JOUR
AB  - With the emergence of the coronavirus disease 2019 pandemic as a threat to mental health, the demand for online interventions that can replace face-to-face approaches for the prevention of mental health problems is increasing. Although several previous reviews on online interventions have targeted adolescents with symptoms of or those diagnosed with mental illness, there is still a lack of evidence on the effectiveness of online preventive interventions for general and at-risk adolescents. Therefore, this review aimed to evaluate the effectiveness of online interventions on the prevention of an increase in the scores of stress, anxiety, and depression in general and at-risk adolescents. A search was performed using PubMed, EMBASE, and Cochrane Library CENTRAL. Altogether, 19 studies were included, and 16 studies were used for the meta-analysis. Our results showed that cognitive behavioral therapy and family-based interventions were most commonly used. Twelve and seven studies conducted universal and selective preventive interventions, respectively. The meta-analysis showed that online interventions significantly prevent an increase in depression score but not in stress and anxiety scores. Evidence regarding the prevention of increases in stress and anxiety scores is limited, suggesting the need for further randomized controlled trials on online interventions for stress and anxiety in adolescents.
AN  - 36181636
AU  - Noh,
AU  - D.
AU  - Kim,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s11121-022-01443-8
L1  - internal-pdf://0848176646/Noh-2022-Effectiveness of Online Interventions.pdf
PY  - 2022
SP  - 01
T2  - Prevention Science
TI  - Effectiveness of Online Interventions for the Universal and Selective Prevention of Mental Health Problems Among Adolescents: a Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36181636
UR  - https://link.springer.com/content/pdf/10.1007/s11121-022-01443-8.pdf
VL  - 01
ER  -
TY  - JOUR
AB  - **Background**
During adolescence, suicide risk increases; effective treatments are needed to reduce risk. 

**Method(s)**
Databases were searched (1995-2020) for randomized controlled trials (RCTs) concerning psychosocial treatments for suicide prevention in adolescents (10-18 yrs). Data were extracted from the timepoint closest to 6 months. Cohen&#039;s ds were estimated for reducing suicidal ideation (SI), self-harming behaviors (SHB) excluding strictly non-suicidal self-injury, and suicide attempts (SA) and analyzed using generalized least square regression. Meta-analytic innovations included within-person correlations to reflect trait suicidality; annualization to control for exposure; estimated lifetime risk based on ages; and modeling inclusion/exclusion criteria. Alternate approaches included relative risk and comparison of intervention and control treatments to baseline. 

**Result(s)**
Of 30 RCTs, 6 assessing SHB (4 measuring SA), and 7 assessing SI demonstrated treatment effectiveness. Overall, interventions decreased SI (n = 25) with low effect size (d = 0.08, p = 0.01), non-significant after controlling for publication bias (d = 0.05, p = 0.1); interventions were non-significant for SHB (n = 25, d = 0.001, p = 0.97) or SA (n = 18, d = 0.03, p = 0.52). To prevent one SHB, the number needed to treat (NNT) was 45[26,156]; for SA, NNT=42[24,149]. Non-superiority may relate to effectiveness of control treatments. Thus, experimental and control treatments also were compared to baseline: both reduced SI (p &lt; 0.0001), and effectiveness improved for SHB (NNT=12) and SA (NNT=11). Limitation(s): Study heterogeneity and inconsistent statistical reporting limited meta-analysis. 

**Conclusion(s)**
Psychosocial interventions for suicide risk in adolescents showed little effectiveness compared with control treatments; suicide outcomes improved in both groups compared to baseline. Different approaches may be needed, including precision medicine methodologies and standardized statistical reporting criteria. Copyright &copy; 2021 Elsevier B.V.
AN  - 2016413398
AU  - Itzhaky,
AU  - L.
AU  - Davaasambuu,
AU  - S.
AU  - Ellis,
AU  - S.
AU  - P.
AU  - Cisneros-Trujillo,
AU  - S.
AU  - Hannett,
AU  - K.
AU  - Scolaro,
AU  - K.
AU  - Stanley,
AU  - B.
AU  - H.
AU  - Mann,
AU  - J.
AU  - J.
AU  - Wainberg,
AU  - M.
AU  - L.
AU  - Oquendo,
AU  - M.
AU  - A.
AU  - Sublette,
AU  - M.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2021.12.094
L1  - internal-pdf://1903925862/Twenty-six years of psychosocial interven-2022.pdf
PY  - 2022
SP  - 511-531
T2  - Journal of Affective Disorders
TI  - Twenty-six years of psychosocial interventions to reduce suicide risk in adolescents: Systematic review and meta-analysis
UR  - https://www.elsevier.com/locate/jad
VL  - 300
ER  -
TY  - JOUR
AB  - The superiority of early interventions for children with autism spectrum disorders (ASDs) compared to treatment as usual (TAU) has recently been questioned. This study was aimed to investigate the efficacy of early interventions in improving the cognitive ability, language, and adaptive behavior of pre-school children with ASDs through a systematic review of randomized controlled trials (RCTs). In total, 33 RCTs were included in the meta-analysis using the random effects model. The total sample consisted of 2581 children (age range: 12-132 months). Early interventions led to positive outcomes for cognitive ability (g = 0.32; 95% CI: 0.05, 0.58; p = 0.02), daily living skills (g = 0.35; 95% CI: 0.08, 0.63; p = 0.01), and motor skills (g = 0.39; 95% CI: 0.16, 0.62; p = 0.001), while no positive outcomes were found for the remaining variables. However, when studies without the blinding of outcome assessment were excluded, positive outcomes of early interventions only remained for daily living skills (g = 0.28; 95% CI: 0.04, 0.52; p = 0.02) and motor skills (g = 0.40; 95% CI: 0.11, 0.69; p = 0.007). Although early intervention might not have positive impacts on children with ASDs for several outcomes compared to controls, these results should be interpreted with caution considering the great variability in participant and intervention characteristics. Copyright &copy; 2022 by the authors.
AN  - 2018992651
AU  - Daniolou,
AU  - S.
AU  - Pandis,
AU  - N.
AU  - Znoj,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/jcm11175100
L1  - internal-pdf://2091234941/Daniolou-2022-The Efficacy of Early Interventi.pdf
PY  - 2022
T2  - Journal of Clinical Medicine
TI  - The Efficacy of Early Interventions for Children with Autism Spectrum Disorders: A Systematic Review and Meta-Analysis
UR  - https://www.mdpi.com/journal/jcm
UR  - https://mdpi-res.com/d_attachment/jcm/jcm-11-05100/article_deploy/jcm-11-05100-v2.pdf?version=1662011427
VL  - 11(17) (no pagination)
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent disorders in children and adolescents. Neurofeedback, a nonpharmaceutical treatment, has shown promising results. To review the evidence of efficacy of neurofeedback as a treatment for children and adolescents with ADHD. A systematic review of the specific scientific studies published in 1995-2021, identifying and analyzing randomized controlled trials (RCT). A total of 1636 articles were identified and 165 met inclusion criteria, of which 67 were RCTs. Neurofeedback training was associated with significant long-term reduction in symptoms of ADHD. Though limitations exist regarding conclusions about the specific effects of neurofeedback, the review documents improvements in school, social, and family environments.
AN  - 35612676
AU  - Moreno-Garcia,
AU  - I.
AU  - Cano-Crespo,
AU  - A.
AU  - Rivera,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10484-022-09547-1
L1  - internal-pdf://0669592339/Results of Neurofeedback in Treatment of-2022.pdf
PY  - 2022
SP  - 25
T2  - Applied Psychophysiology &amp; Biofeedback
TI  - Results of Neurofeedback in Treatment of Children with ADHD: A Systematic Review of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35612676
UR  - https://link.springer.com/article/10.1007/s10484-022-09547-1
UR  - https://link.springer.com/content/pdf/10.1007/s10484-022-09547-1.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - Neurofeedback training is a common treatment option for attention deficit hyperactivity disorder (ADHD). Given theta/beta-based neurofeedback (T/B NF) training targets at the electrophysiological characteristics of children with ADHD, benefits for attention may be expected. PsycINFO, PubMed, ScienceDirect, Scopus, and Web of Science were searched through December 31, 2020. Studies were evaluated with Risk of Bias tools. Within-group effects based on Pre- and Post-treatment comparisons of the Intervention Group, and Between-group effects based on the between-group differences from Pre-treatment to Post-treatment were calculated. Nineteen studies met selection criteria for systematic review, 12 of them were included in meta-analysis. Within-group effects were medium at Post-treatment and large at Follow-up. Between-group analyses revealed that T/B NF was superior to waitlist control and physical activities, but not stimulant medication. Results showed that T/B NF has benefits for attention in children with ADHD, however, cautions should be taken when interpreting the findings.
AN  - 35471754
AU  - Lee,
AU  - C.
AU  - S.
AU  - C.
AU  - Chen,
AU  - T.
AU  - T.
AU  - Gao,
AU  - Q.
AU  - Hua,
AU  - C.
AU  - Song,
AU  - R.
AU  - Huang,
AU  - X.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10578-022-01361-4
L1  - internal-pdf://1900697275/The Effects of Theta_Beta-based Neurofeed-2022.pdf
PY  - 2022
SP  - 26
T2  - Child Psychiatry &amp; Human Development
TI  - The Effects of Theta/Beta-based Neurofeedback Training on Attention in Children with Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35471754
UR  - https://link.springer.com/content/pdf/10.1007/s10578-022-01361-4.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - BAKGRUNN:
Denne artikkelen oppsummerer kunnskapen om effektene av PMTO-foreldregruppe (tidligere kalt TIBIR &ndash; Foreldregruppeintervensjonen) som intervensjon i TIBIR-programmet. Artikkelen er en revisjon av en tidligere beskrivelse av det samme tiltaket i Ungsinn, men er videreutviklet i henhold til Ungsinns nye kriterier og prosedyrer. Intervensjonen baserer seg på prinsippene fra Parent Management Training Oregonmodellen (PMTO), med det unntaket at i denne intervensjonen møtes foreldrene i grupper over 12 samlinger. Det deltar inntil 12 foreldre/foresatte i gruppene og gruppen ledes av to gruppeledere. Målgruppen for tiltaket er foreldre og foresatte til barn med begynnende atferdsproblemer, men tiltaket kan også tilbys til familier som har barn med identifiserte atferdsproblemer.

METODE:
Følgende databaser ble gjennomsøkt etter litteratur om tiltaket: Embase, Medline, Psychinfo, Cochrane, Cristin, Nora, Scopus og Svemed.

RESULTATER:
Tre studier som omhandlet PMTO&ndash;foreldregruppe ble identifisert og inkludert. Det er gjennomført tre norske studier; en effektstudie blant norske foreldre og to studier med henholdsvis foreldre med minoritetsbakgrunn og fosterforeldre. Det foreligger en god beskrivelse av tiltaket i manualer, og tiltaket har en god teoretisk begrunnelse. Alle studiene er evaluert til å ha tilfredsstillende til god forskningsmetodisk kvalitet. Effektstørrelsene i de to studiene der disse er beregnet er i hovedsak små til moderate. Tiltaket har en god implementeringsstrategi og gode rutiner for å sikre at innholdet i tiltaket og effektene opprettholdes.

KONKLUSJON:
Studiene som evaluerer tiltaket har relativt god forskningsmetodisk kvalitet, og effektstørrelser beregnet til små til store. Hovedfunnene i de inkluderte studiene trekker alle i retning av at barnas atferdsproblemer reduseres som følge av tiltaket, samt at foreldreferdigheter styrkes. Det antas derfor at tiltaket vil være nyttig for mange i målgruppen.PMTO-foreldregruppe klassifiseres på evidensnivå 4 &ndash; som et tiltak med tilfredsstillende dokumentasjon på effekt.
AU  - Adolfsen,
AU  - F.
AU  - Reedtz,
AU  - C.
AU  - Koposov,
AU  - R.
AU  - Fossum,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /post_tiltak_arkiv/pmto-foreldregruppe/
L1  - internal-pdf://0865934730/PMTO-foreldregruppe-Final.pdf
PY  - 2022
T2  - Ungsinn
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: PMTO-foreldregruppe (2. utg.)
ER  -
TY  - JOUR
AB  - Indigenous Peoples (IP) face significant health disparities that stem from historical trauma (HT). This is the first systematic review to investigate mental health interventions that address HT in addition to treating mental health disorders among IP in the United States. The data search included seven databases for published studies, consultations with experts, hand searching journals, and reference list checking. Five studies met the inclusion criteria and were included in the review. In total, 608 clients were examined. Findings suggested that treatments that addressed HT had a marginally beneficial effect on psychological and HT symptom outcomes. However, one study found that the intervention was not successful at maintaining these gains. Due to the limited number of studies, and the heterogeneity of research findings and the methodological limitations suffered by included studies, no definite conclusions about mental health interventions that address HT can be drawn. Recommendations for practice, such as using traditional healing practices for IP in mental health interventions, and recommendations for future research are provided.
AN  - WOS:000786587600001
AU  - Sevillano,
AU  - L.
AU  - Wood,
AU  - B.
AU  - Franklin,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1093/swr/svac007
L1  - internal-pdf://0730673876/Mental Health Interventions That Address-2022.pdf
PY  - 2022
SP  - 127-140
T2  - Social Work Research
TI  - Mental Health Interventions That Address Historical Trauma among Indigenous Peoples: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000786587600001
UR  - https://academic.oup.com/swr/article-abstract/46/2/127/6563098?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/svac007.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAs8wggLLBgkqhkiG9w0BBwagggK8MIICuAIBADCCArEGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMOzRdnP9zssZbfbvpAgEQgIICgkRvewzrDGI_jOfM9qDrpmJzYW7tGIxbrq6X5kF9gYf-W_NQf8758c_0tYtz50CgIHTFLpSNx2oHvJWVWf3rIlpEg3yFc7WQR-RXt0aK1_RjgEQeKez8mK3bfgVbF1WmwwFmJCAxdbCzK-rCOFeKkPh3BqDV8o8VidYFuk2OLBUwooqrktd6ybnHVBBN1X1YiAsFg5QzteJLrjKfwJNrnG37EdOrNSYjC0PvkDt4eMp-8IknbZr-y0CFAjmQFiN6Vt7VNQM7M-hz0ifMv6yhXZlMepYZCOPPx6agH302vH1ZO5Czu-4Ktie0AVlLO89dRtGmg5IqXUtopfd71RXPfr7H-4kBjIY4E4-z2aUWW6NkEyqo7rPJ6hcPhPtRNwnR5RF7Gqu98O7jrZ2AVs2L1-k1YB7gICALIDBCKhv4Vc4NHkpyNohv503kxZQcELYUEcd1W4OzILx7JnmeJgFVfa-aPKaDwbhNqwZVmjsl0bUNkLcwEOi71hh3hmnwJLryWAtYxBNWhfbRIH164Xc5ZMyuT_43yvSbvMfn0EtX9pr2F6Q_Qzkonq5XqpaA7eaT5jgFGWVgdBwpvN_U4C_XfBOaQlBZODyCYVKKTBObVravS2uGUzJ_oaYLSV4IyFq4oaV4uAM4YSUARgb_f7J22HdaB3bXU5vpA4JfJgqzBCp-Ljo7K9j5hqATwk7mBycXlIm09FI5udD6-xAFXTZ7cdMEcJ_eLvgUZTlDXQvAQiM9ibhozP-sTRgI2CO1_2mv_kf97A0EA2Ac7keZn6WsS_3SiiE-y3ZVnpHpvoxAPLXcZvowJdf-RzLAakPHu-mKFnZwm8sj4Z_QJKOTK_jsMc9VYg
VL  - 46
ER  -
TY  - JOUR
AB  - **Objective**
To quantitatively synthesize the literature on the effects of repetitive transcranial magnetic stimulation (rTMS) on suicidal ideation (SI) in patients with treatment-resistant depression. 

**Data Sources** 
A literature search was conducted using PubMed, SCOPUS, Ovid, MEDLINE, Embase, and Web of Science from inception to January 11, 2021, for the keywords repetitive transcranial magnetic stimulation, suicidal ideation, suicidality, treatment-resistant depression, refractory depression, transcranial magnetic stimulation, and brain stimulation. 

**Study Selection**
A total of 16 publications were eligible for inclusion. Studies were included that investigated the effects of rTMS in adolescents and/or adults 16 years or older diagnosed with unipolar or bipolar depression with suicidal ideation data before and after rTMS intervention. 

**Data Extraction**
Data were extracted and managed using Covidence. Extracted data included authors, publication year, country of origin, study design, patient demographics, primary diagnosis, comorbidities, mean age, outcome assessment instruments, detailed stimulation parameters, sham control procedures, and any serious adverse events related to SI. 

**Results**
A quantitative analysis of effect size using Hedges g was calculated for both randomized controlled trials and all other uncontrolled trials. We found a decrease in SI scores in randomized controlled trials (g = 0.158, 95% confidence interval [CI] = -0.078 to 0.393, P = .191), although the effect was not significant. There was a significant decrease in suicidal ideation scores for uncontrolled trials (g = 0.692, 95% CI = 0.463 to 0.922, P &lt; .001). 

**Conclusions**
Our findings suggest that rTMS may be an effective treatment for SI in individuals with treatment-resistant depression, although further investigation is warranted.
AN  - 35044731
AU  - Mehta,
AU  - S.
AU  - Konstantinou,
AU  - G.
AU  - Weissman,
AU  - C.
AU  - R.
AU  - Daskalakis,
AU  - Z.
AU  - J.
AU  - Voineskos,
AU  - D.
AU  - Downar,
AU  - J.
AU  - Mulsant,
AU  - B.
AU  - H.
AU  - Blumberger,
AU  - D.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.4088/JCP.21r13969
L1  - internal-pdf://3085279563/The Effect of Repetitive Transcranial Mag-2022.pdf
PY  - 2022
SP  - 18
T2  - Journal of Clinical Psychiatry
TI  - The Effect of Repetitive Transcranial Magnetic Stimulation on Suicidal Ideation in Treatment-Resistant Depression: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=35044731
VL  - 83
ER  -
TY  - JOUR
AB  - The prevalence of bullying worldwide is high (UNESCO, 2018). Over the past decades, many anti-bullying interventions have been developed to remediate this problem. However, we lack insight into for whom these interventions work and what individual intervention components drive the total intervention effects. 

We conducted a large-scale individual participant data (IPD) meta-analysis using data from 39,793 children and adolescents aged five to 20 years (M-age = 12.58, SD = 2.34) who had participated in quasi-experimental or randomized controlled trials of school-based anti-bullying interventions (i.e., 10 studies testing nine interventions). Multilevel logistic regression analyses showed that anti-bullying interventions significantly reduced self-reported victimization (d = - 0.14) and bullying perpetration (d = - 0.07). Anti-bullying interventions more strongly reduced bullying perpetration in younger participants (i.e., under age 12) and victimization for youth who were more heavily victimized before the intervention. We did not find evidence to show that the inclusion of specific intervention components was related to higher overall intervention effects, except for an iatrogenic effect of non-punitive disciplinary methods-which was strongest for girls. Exploratory analyses suggested that school assemblies and playground supervision may have harmful effects for some, increasing bullying perpetration in youth who already bullied frequently at baseline. 

In conclusion, school-based anti-bullying interventions are generally effective and work especially well for younger children and youth who are most heavily victimized. Further tailoring of interventions may be necessary to more effectively meet the needs and strengths of specific subgroups of children and adolescents.
AN  - WOS:000821714000002
AU  - Hensums,
AU  - M.
AU  - de
AU  - Mooij,
AU  - B.
AU  - Kuijper,
AU  - S.
AU  - C.
AU  - Fekkes,
AU  - M.
AU  - Overbeek,
AU  - G.
AU  - BIRC:
AU  - the
AU  - anti-Bullying
AU  - Interventions
AU  - Research
AU  - Consortium,
DB  - Alerts 6_2022.enl
DO  - 10.1007/s11121-022-01387-z
L1  - internal-pdf://2912601513/Hensums-What Works for Whom in School-Based An.pdf
PY  - 2022
SP  - 12
T2  - Prevention Science
TI  - What Works for Whom in School-Based Anti-bullying Interventions? An Individual Participant Data Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000821714000002
UR  - https://link.springer.com/content/pdf/10.1007/s11121-022-01387-z.pdf
ER  -
TY  - JOUR
AB  - Functional communication training, an intervention for challenging behavior rooted in principles of applied behavior analysis, has copious empirical support dating back to the mid-1980s for autistic individuals. Recently, there has been a concerted effort to thin reinforcement delivery during functional communication training using contingency-based delays that, in turn, are designed to enhance practicality and feasibility while not compromising on efficacy.

In this synthesis, we meta-analyzed the literature using log response ratio effect sizes to investigate (a) combined and across type effectiveness of contingency-based delays and (b) moderating variables that might impact intervention outcomes. 

Findings showed that contingency-based delays were effective for autistic individuals (log response ratio = -2.17; 95% CI = (-2.76, -1.58)) and most effective when the contingency incorporated positive reinforcement (log response ratio = -2.30; 95% CI = (-2.83, -1.78)). In addition, delay procedures that included differential reinforcement of alternative behavior were overall more effective (log response ratio = -2.13; 95% CI = (-2.72, -1.55)) than those that involved differential reinforcement of other behavior (log response ratio = -1.24; 95% CI = (-3.84, 1.37)). Noteworthy moderating variables found to impact contingency-based delay efficacy included the intervention dosage and the topography of behavior. 

We discuss these findings and highlight directions where additional empirical research is warranted to improve our understanding about contingency-based delays for autistic individuals. Lay abstract Functional communication training, an intervention for challenging behavior rooted in principles of applied behavior analysis, has copious empirical support dating back to the mid-1980s for autistic individuals. Recently, there has been a concerted effort to thin reinforcement delivery during functional communication training using contingency-based delays that, in turn, are designed to enhance practicality and feasibility while not compromising efficacy. 

In this synthesis, we meta-analyzed the literature base with the goal of investigating both combined and across type effectiveness of contingency-based delays. We also aimed to investigate moderating variables that might impact intervention outcomes. Findings showed that contingency-based delays were effective for individuals with an autism spectrum disorder diagnosis and most effective when the delay incorporated some form of positive reinforcement. In addition, differential reinforcement of alternative-based delays was overall more effective when compared to differential reinforcement of other behavior-based delays. Noteworthy moderating variables found to impact contingency-based delay efficacy included the intervention dosage and the topography of behavior. We discuss these findings and highlight directions where additional empirical research is warranted to improve our understanding about contingency-based delays for individuals diagnosed with autism spectrum disorder.
AN  - WOS:000738645000001
AU  - Muharib,
AU  - R.
AU  - Dowdy,
AU  - A.
AU  - Rajaraman,
AU  - A.
AU  - Jessel,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/13623613211065540
L1  - internal-pdf://0348300220/Contingency-based delay to reinforcement follo.pdf
PY  - 2022
SP  - 21
T2  - Autism
TI  - Contingency-based delay to reinforcement following functional communication training for autistic individuals: A multilevel meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000738645000001
ER  -
TY  - JOUR
AB  - OBJECTIVE: To examine child behavior change scores from randomized controlled trials (RCTs) of parent interventions for pediatric traumatic brain injury (TBI). 

METHODS: MEDLINE, EMBASE, PsycINFO, and CINAHL were searched to identify studies that examined parent interventions for pediatric TBI. Inclusion criteria included (i) a parent intervention for children with TBI; (ii) an RCT study design; (iii) statistical data for child behavior outcome(s); and (iv) studies that were published in English. 

RESULTS: Seven studies met inclusion criteria. All interventions reported improved child behavior after pediatric TBI; however, child and parent factors contributed to behavior change scores in some interventions. Factors found to contribute to the level of benefit included age of child, baseline behavior levels, sociodemographics (eg, parent income, parent education), and parent mental health. 

CONCLUSION: Improved child behavior outcomes resulting from parent interventions for pediatric TBI are well supported by the evidence in the peer-reviewed literature. Clinicians are encouraged to consider child and parent factors as they relate to child behavior outcomes.
AN  - 35125430
AU  - Cermak,
AU  - C.
AU  - A.
AU  - McCabe,
AU  - S.
AU  - A.
AU  - Kuchurean,
AU  - B.
AU  - Schaefer,
AU  - J.
AU  - Tendera,
AU  - A.
AU  - Beal,
AU  - D.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/HTR.0000000000000766
L1  - internal-pdf://0712306379/Parent Interventions Improve Behavior Aft-2022.pdf
PY  - 2022
SP  - 01
T2  - Journal of Head Trauma Rehabilitation
TI  - Parent Interventions Improve Behavior After Pediatric Traumatic Brain Injury: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35125430
VL  - 01
ER  -
TY  - JOUR
AB  - The objective of this study is to conduct a systematic review and meta-analysis to assess the effect of psychosocial interventions in reducing problematic Internet use (PIU), anxiety, and depression symptoms in a sample of people. 

This review was registered on the PROSPERO database (CRD42020181912) and a total of 15 studies were included. Analyses of the effect of the interventions were conducted based on the standardized mean difference of the studied outcomes (PIU, anxiety, and depression). 

Most studies reported a positive effect of psychosocial interventions on reducing symptoms of PIU, depression, and anxiety among people with PIU. However, only one detected a robust effect in reducing symptoms of anxiety. For depression, this effect was more modest, and there was no difference between the different modalities of psychosocial interventions. 

The results suggest that psychosocial interventions are effective in reducing both symptoms of PIU and co-occurring symptoms of depression and anxiety in individuals with PIU.
AN  - WOS:000805717700001
AU  - Andrade,
AU  - A.
AU  - L.
AU  - M.
AU  - Martins,
AU  - G.
AU  - D.
AU  - Scatena,
AU  - A.
AU  - Lopes,
AU  - F.
AU  - M.
AU  - de
AU  - Oliveira,
AU  - W.
AU  - A.
AU  - Kim,
AU  - H.
AU  - S.
AU  - De
AU  - Micheli,
AU  - D.
DB  - Alerts 6_2022.enl
DO  - 10.1007/s11469-022-00846-6
L1  - internal-pdf://0653965809/Andrade-The Effect of Psychosocial Interventio.pdf
PY  - 2022
SP  - 22
T2  - International Journal of Mental Health and Addiction
TI  - The Effect of Psychosocial Interventions for Reducing Co-occurring Symptoms of Depression and Anxiety in Individuals with Problematic Internet Use: A Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000805717700001
UR  - https://link.springer.com/content/pdf/10.1007/s11469-022-00846-6.pdf
ER  -
TY  - JOUR
AB  - OBJECTIVES: Children with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) experience a higher prevalence of depression and anxiety compared with age-matched controls. Our previous systematic reviews in 2015/16 found little evidence for effective treatment for children with CFS/ME with comorbid depression and/or anxiety. This review updates these findings. 

DESIGN: A systematic review. We searched Cochrane library, Medline, Embase and PsycINFO databases from 2015 to 2020. We combined the updated results with our previous reviews in a narrative synthesis. 

PARTICIPANTS: Inclusion criteria: &lt;18 years old; diagnosed with CFS/ME (using Centers for Disease Control and Prevention, National Institute for Health and Care Excellence or Oxford criteria); validated measures of depression and/or anxiety. 

INTERVENTIONS: Observational studies or randomised controlled trials. 

COMPARISON: Any or none. OUTCOMES: Studies with outcome measures of anxiety, depression or fatigue. 

RESULTS: The updated review identified two studies. This brings the total number of paediatric CFS/ME studies with a measure of anxiety and/or depression since 1991 to 16. None of the studies specifically targeted depression, nor anxiety. One new study showed the Lightning Process (in addition to specialist care) was more effective at reducing depressive and anxiety symptoms compared with specialist care alone. Previous studies evaluated cognitive-behavioural therapy (CBT); pharmacological interventions and behavioural approaches. CBT-type interventions had most evidence for improving comorbid anxiety and/or depressive symptoms but varied in delivery and modality. Other interventions showed promise but studies were small and have not been replicated. 

CONCLUSION: Very few paediatric CFS/ME intervention studies have been conducted. This review update does not significantly add to what is known from previous reviews. The evidence is of poor quality and insufficient to conclude which interventions are effective at treating comorbid anxiety and/or depression in paediatric CFS/ME. PROSPERO REGISTRATION NUMBERS: CRD42016043488 and CRD42015016813.
AN  - 35105619
AU  - Clery,
AU  - P.
AU  - Royston,
AU  - A.
AU  - Driver,
AU  - K.
AU  - Bailey,
AU  - J.
AU  - Crawley,
AU  - E.
AU  - Loades,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/bmjopen-2021-051358
L1  - internal-pdf://3182555342/What treatments work for anxiety and depr-2022.pdf
PY  - 2022
SP  - e051358
T2  - BMJ Open
TI  - What treatments work for anxiety and depression in children and adolescents with chronic fatigue syndrome? An updated systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=35105619
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808375/pdf/bmjopen-2021-051358.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **Background**
People who experience incarceration die by suicide at a higher rate than those who have no prior criminal justice system contact, but little is known about the effectiveness of interventions in other criminal justice settings. We aimed to synthesise evidence regarding the effectiveness of interventions to reduce suicide and suicide-related behaviours among people in contact with the criminal justice system. 

**Methods**
We searched Embase, PsycINFO, MEDLINE, and grey literature databases for articles published between 1 January 2000 and 1 June 2021. The protocol was registered with PROSPERO (CRD42020185989). 

**Findings**
Thirty-eight studies (36 primary research articles, two grey literature reports) met our inclusion criteria, 23 of which were conducted in adult custodial settings in high-income, Western countries. Four studies were randomised controlled trials. Two-thirds of studies (n=26, 68%) were assessed as medium quality, 11 (29%) were assessed as high quality, and one (3%) was assessed as low quality. Most had considerable methodological limitations and very few interventions had been rigorously evaluated; as such, drawing robust conclusions about the efficacy of interventions was difficult.

**Interpretation**
More high-quality evidence from criminal justice settings other than adult prisons, particularly from low- and middle-income countries, should be considered a priority for future research. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.
AN  - WOS:000801916100008
AU  - Carter,
AU  - A.
AU  - Butler,
AU  - A.
AU  - Willoughby,
AU  - M.
AU  - Janca,
AU  - E.
AU  - Kinner,
AU  - S.
AU  - A.
AU  - Southalan,
AU  - L.
AU  - Fazel,
AU  - S.
AU  - Borschmann,
AU  - R.
DB  - Alerts 6_2022.enl
DO  - 10.1016/j.eclinm.2021.101266
L1  - internal-pdf://4114398228/1-s2.0-S2589537021005472-main.cleaned.pdf
PY  - 2022
SP  - 19
T2  - EClinicalMedicine
TI  - Interventions to reduce suicidal thoughts and behaviours among people in contact with the criminal justice system: A global systematic review
UR  - &lt;Go to ISI&gt;://WOS:000801916100008
UR  - https://www.sciencedirect.com/science/article/pii/S2589537021005472?via%3Dihub
VL  - 44
ER  -
TY  - JOUR
AB  - **INTRODUCTION**
The aim of this systematic review was to assess the effectiveness of brief interventions realized in primary care in reducing cannabis use for adolescents and emerging adults. 

**METHODS**
PubMed, CINAHL, Embase, PsycInfo, and Central (Cochrane Library) were searched until December 2020. Randomized controlled trials conducted in primary care, concerning in-person brief interventions for non-medical cannabis users aged from 12 to 25 years old were eligible for inclusion. Brief interventions had to last 30 min or less. Patients with comorbid mental health disorder or very specific populations were not included. 

**RESULTS**
One thousand eighty hundred and fifty-five studies were identified through database searching; only 8 studies involving 2,199 patients were included for qualitative synthesis after double reading and data extraction. Randomized controlled trials selected were heterogeneous regarding screening tools, initial levels of cannabis use and cannabis outcomes measures. Brief interventions were all based on motivational interviewing techniques or personalized feedback. Seven studies consisted in a single session of brief intervention. Six studies involved also other substance users. No significant reduction of cannabis use after brief intervention was found for most studies, especially in the long term. A trend of decreased cannabis consequences, such as negative psychosocial repercussions, perception of cannabis use by peers, or driving under the influence of cannabis, was reported. 

**CONCLUSION**
The current state of knowledge does not allow us to say that the brief intervention is effective in reducing cannabis use among adolescents in primary care. We found a mild positive effect on cannabis consequences after brief intervention. Mixed qualitative and quantitative studies are need to better evaluate the impact of brief intervention and his faisability. PROSPERO (International Prospective Register of Systematic Reviews): ndegree CRD42016033080.
AN  - 35696124
AU  - Chazal,
AU  - C.
AU  - Roux,
AU  - C.
AU  - Kinouani,
AU  - S.
AU  - Schuers,
AU  - M.
AU  - Fortin,
AU  - F.
AU  - Pereira,
AU  - B.
AU  - Blanc,
AU  - O.
AU  - Pinol-Domenech,
AU  - N.
AU  - Brousse,
AU  - G.
AU  - Vorilhon,
AU  - P.
AU  - Laporte,
AU  - C.
DB  - Alerts 6_2022.enl
DO  - /10.1093/fampra/cmac050
L1  - internal-pdf://1599323250/Chazal-2022-Effectiveness of brief interventio.pdf
PY  - 2022
SP  - 13
T2  - Family Practice
TI  - Effectiveness of brief interventions in primary care for cannabis users aged from 12 to 25 years old: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35696124
UR  - https://academic.oup.com/fampra/advance-article-abstract/doi/10.1093/fampra/cmac050/6607695?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/cmac050.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAvAwggLsBgkqhkiG9w0BBwagggLdMIIC2QIBADCCAtIGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM1wCixjwK01TnRIOnAgEQgIICo2SmDV6DYjLWU6aPzdTwf58SANVOfgzKMiSaL0LEMZ43opiCoiVLRl1sOEj0ldPE0ogVCSBAswu8MhxDfkf8Rdomg6YolaASqau4e7o08_EENbq8OlG-WFdI0lATKNXiN2GSfN26rp0_e7uhNMSWTg5VUXRvZyd1CAmw8oF6nGxQ7FIR92FsXj_PrO3KMBelwv1Zmgi7I6z3tn-fuGkb5hpciGOrC8fy4djMsEWAapaQ4gQAmo9dudMX_DlDkca6cpg7d5ndaq9A9Kyc9djSmZKF7_P0V_5nDhQ1FnEWLGE4uE5N8-jT83b1xm8jla5H0XnJjFILZQYTuCNaiUeZ9HQXTIdbMLVD2hYbCk-RdGO9TztBjzaT7CfugT_pZwtiS8Ms1ym5vY86FMN22JKDZBGGGoPQ1BmXzP7jJSQ6Lh7XiTxqEHG8Pr56jSK1mGkCvxCMgqGC1srGxnOq6D4-aZ8dvySnub1O22-e-Hu0_Ukpl_6cOmswYDHfz4tgJfxWxNp4UPzb4It4VT59B6ljwBEGiMWfTCniVutSqc1zY123vN0APV30QIXrmmJZP0JOyoQWlQ8Bfo_vNN1Yp_e47RHcDzsb8CVnAD-CGlEhXlJ5W496iKgGu1BmQJQpw8q11foD0DDg-BuecCvXs41jh6c5Qzj32iAGCoxAcI0L1gn6bRIrBmaYsEnd8poGvmfeXPRBw5pDZR7g2EuMfyF68v5Z0QYkT6I1-Qye28ofuNeLHivdKNhxu27suAy4oMTPqJtxrHfKcPWP81G2-TYGr0EdcirpR6pugbl6xhMr0J21gMAAFW5gETTzbCphAwlN2DFpJHigrd9vo08PeOI2b_MPwhDC3Q3u-p9f75Ahrydk7wpCz9aNj8s0bUsDwXdufwlZcA
VL  - 13
ER  -
TY  - JOUR
AB  - OBJECTIVE: The present study was aimed at analyzing the effect of physical activity on motor coordination in children with ASD. 

METHODS: On 28 June 2021, a systematic review with meta-analysis was performed using the following databases: MEDLINE, SciELO, LILACS, PEDro, SPORTDiscus, CINAHL, SCOPUS, Web of Science, Cochrane, and Science Direct. We analyzed the methodological quality and risk of bias using the Jadad scale and Cochrane tool, respectively. Motor coordination results were meta-analyzed using the RevMan program. Two independent researchers used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) tool to assess the level of evidence from the meta-analysis. 

RESULTS: We found four studies in the listed databases and five randomized clinical trials were included in the meta-analysis that included 109 children with ASD. Children with ASD who performed physical activity did not present significantly better motor coordination than control children (p = 0.12). 

CONCLUSIONS: Considering the clinical importance of physical activity for children with ASD, this systematic review with meta-analysis showed that physical activity had no statistically significant effects on coordination in individuals with ASD.
AN  - 36360956
AU  - Monteiro,
AU  - C.
AU  - E.
AU  - Da
AU  - Silva,
AU  - E.
AU  - Sodre,
AU  - R.
AU  - Costa,
AU  - F.
AU  - Trindade,
AU  - A.
AU  - S.
AU  - Bunn,
AU  - P.
AU  - Costa,
AU  - E.
AU  - Silva
AU  - G.
AU  - Di
AU  - Masi,
AU  - F.
AU  - Dantas,
AU  - E.
DB  - Alerts 6_2022.enl
DO  - /10.3390/ijerph192114081
L1  - internal-pdf://1991168892/Monteiro-2022-The Effect of Physical Activity.pdf
PY  - 2022
SP  - 28
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - The Effect of Physical Activity on Motor Skills of Children with Autism Spectrum Disorder: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=36360956
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-19-14081/article_deploy/ijerph-19-14081-v2.pdf?version=1667180303
VL  - 19
ER  -
TY  - JOUR
AB  - **QUESTION**
Mindfulness-based programmes (MBPs) are an increasingly popular approach to improving mental health in young people. Our previous meta-analysis suggested that MBPs show promising effectiveness, but highlighted a lack of high-quality, adequately powered randomised controlled trials (RCTs). This updated meta-analysis assesses the-state-of the-art of MBPs for young people in light of new studies. It explores MBP&#039;s effectiveness in active vs passive controls; selective versus universal interventions; and studies that included follow-up. 

**STUDY SELECTION AND ANALYSIS**
We searched for published and unpublished RCTs of MBPs with young people (&lt;19 years) in PubMed Central, PsycINFO, Web of Science, EMBASE, ICTRP, ClinicalTrials.gov, EThOS, EBSCO and Google Scholar. Random-effects meta-analyses were conducted, and standardised mean differences (Cohen&#039;s d) were calculated. 

**FINDINGS**
Sixty-six RCTs, involving 20 138 participants (9552 receiving an MBP and 10 586 controls), were identified. Compared with passive controls, MBPs were effective in improving anxiety/stress, attention, executive functioning, and negative and social behaviour (d from 0.12 to 0.35). Compared against active controls, MBPs were more effective in reducing anxiety/stress and improving mindfulness (d=0.11 and 0.24, respectively). In studies with a follow-up, there were no significant positive effects of MBPs. No consistent pattern favoured MBPs as a universal versus selective intervention. 

**CONCLUSIONS**
The enthusiasm for MBPs in youth has arguably run ahead of the evidence. While MBPs show promising results for some outcomes, in general, the evidence is of low quality and inconclusive. We discuss a conceptual model and the theory-driven innovation required to realise the potential of MBPs in supporting youth mental health.
AN  - 35820989
AU  - Dunning,
AU  - D.
AU  - Tudor,
AU  - K.
AU  - Radley,
AU  - L.
AU  - Dalrymple,
AU  - N.
AU  - Funk,
AU  - J.
AU  - Vainre,
AU  - M.
AU  - Ford,
AU  - T.
AU  - Montero-Marin,
AU  - J.
AU  - Kuyken,
AU  - W.
AU  - Dalgleish,
AU  - T.
DB  - Alerts 6_2022.enl
DO  - /10.1136/ebmental-2022-300464
L1  - internal-pdf://3758866256/Dunning-2022-Do mindfulness-based programmes i.pdf
PY  - 2022
SP  - 12
T2  - Evidence Based Mental Health
TI  - Do mindfulness-based programmes improve the cognitive skills, behaviour and mental health of children and adolescents? An updated meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35820989
UR  - https://ebmh.bmj.com/content/ebmental/25/3/135.full.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Group social skills interventions (GSSIs) are offered to youth with Autism Spectrum Disorder (ASD) to improve social functioning. This systematic review focused on the adolescent population, including a wider range of disabilities. AIMS: To evaluate effectiveness of GSSIs at improving social functioning in adolescents with congenital, acquired or developmental disabilities. 

METHODS AND PROCEDURES: 
Databases, trial registries and dissertations were systematically searched and a meta-analysis of randomized controlled trials conducted. Study screening, risk-of-bias assessment and Grading of Recommendations Assessment, Development and Evaluation were completed. 

OUTCOMES AND RESULTS: 
Sixteen studies (n=1119), 15 with adolescents with ASD and one with brain tumor survivors, revealed GSSIs reduced social impairment on the Social Responsiveness Scale (mean difference (MD) 9.68, 95% CI 5.63-13.73; P&lt;0.001), increased social skills on the Social Skill Improvement System Rating Scales (SMD 0.38, 95% CI 0.10-0.65; P=0.007), and improved adolescent social knowledge on the Test of Adolescent Social Skills (MD 7.43 points, 95% CI 5.36-9.50; P&lt;0.001). 

CONCLUSIONS AND IMPLICATIONS: 
There is moderate certainty evidence that GSSIs improve social responsiveness, social skills and knowledge, and low certainty of evidence to improve social participation for adolescents with ASD. High quality randomized studies are required to inform clinical practice with adolescents with other disabilities. WHAT THIS PAPER ADDS: Current evidence for group social skills interventions (GSSIs) is for adolescents with autism (ASD). GSSIs likely improve social knowledge and reduce impairments in adolescents with ASD, however the effect of GSSIs on social participation is not well understood. Only one randomized trial investigated GSSIs in another population of adolescents, highlighting the need for more high-quality studies including adolescents with other disabilities.
AN  - 35306461
AU  - Gilmore,
AU  - R.
AU  - Ziviani,
AU  - J.
AU  - Chatfield,
AU  - M.
AU  - D.
AU  - Goodman,
AU  - S.
AU  - Sakzewski,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ridd.2022.104218
L1  - internal-pdf://3703737038/Social skills group training in adolescen-2022.pdf
PY  - 2022
SP  - 104218
T2  - Research in Developmental Disabilities
TI  - Social skills group training in adolescents with disabilities: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35306461
UR  - https://www.sciencedirect.com/science/article/pii/S0891422222000488?via%3Dihub
VL  - 125
ER  -
TY  - JOUR
AB  - **Objective:**
To synthesize the evidence on the efficacy of ADHD teacher training interventions for teachers&rsquo; ADHD knowledge and reducing pupils&rsquo; ADHD-type behaviors.

**Method:**
Six electronic databases were systematically searched up to 14/04/20. Meta-analyses were performed to pool standardized mean differences (SMD).

**Results:**
29 studies were included in the systematic review, and 22 meta-analyzed. SMD for teacher knowledge within subjects at post-test and follow-up was 1.96 (95% confidence interval = 1.48, 2.43) and ‒1.21 (&ndash;2.02, &ndash;0.41) respectively. Between subjects analyses at post-test showed SMD = 1.56 (0.52, 2.59), with insufficient data at follow-up. At post-test, SMD for pupils&rsquo; behavior within and between subjects was 0.78 (0.37, 1.18), and 0.71 (&ndash;0.11, 1.52), respectively. Medium-to-high risk of bias was found in all but one study.

**Conclusion:**
ADHD teacher training programs may be effective in initially improving ADHD teachers&rsquo; knowledge. There is inconsistent evidence for their efficacy to reduce students&rsquo; ADHD-type behaviors.
AN  - 2022-14815-003
AU  - Ward,
AU  - Rebecca
AU  - J.
AU  - Bristow,
AU  - Sarah
AU  - J.
AU  - Kovshoff,
AU  - Hanna
AU  - Cortese,
AU  - Samuele
AU  - Kreppner,
AU  - Jana
DB  - Alle inkluderte systematiske oversikter i IN SUM-Converted.enl
DO  - /10.1177/1087054720972801
L1  - internal-pdf://3398329417/Ward-2022-The effects of ADHD teacher training.pdf
PY  - 2022
SP  - 225-244
T2  - Journal of Attention Disorders
TI  - The effects of ADHD teacher training programs on teachers and pupils: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc22&amp;AN=2022-14815-003
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679179/pdf/10.1177_1087054720972801.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - GenerationPMTO is a theory- and evidence-based behavioral parenting program widely implemented in the past three decades. This systematic review and meta-analysis examined the effectiveness of twenty GenerationPMTO studies on parenting and child adjustment among 3893 families in six countries. 

Hedges&#039; g from studies with pretest-posttest-controlled designs were computed and robust variance estimation (RVE) was used to deal with the effect size dependency. 

Results showed that GenerationPMTO significantly promoted parenting and child adjustment with moderate to high levels of heterogeneity. Specifically, GenerationPMTO improved parental discipline, parenting monitoring, skill encouragement, child externalizing problems, and child internalizing problems. Subgroup analyses revealed several important moderators, including type of comparison group, measurement, informant, risk of bias, etc. Intervention effects were quite robust across countries and multiple demographic characteristics. No publication bias across studies for parenting and child adjustment was detected. The revised Cochrane risk of bias for randomized trials (RoB 2) procedure was used to assess risk of bias within the included studies. Some studies showed a higher level of risk due to problems with the randomization process, missing data, low measurement quality, and reporting bias. Due to lack of data, we did not examine intervention effects on parental mental health or couple relationship quality. 

Future studies should test mediation models to understand the mechanisms of change and to identify moderators in order to understand the high levels of heterogeneity in GenerationPMTO studies. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-71341-001
AU  - Cai,
AU  - Q.
AU  - Chan,
AU  - A.
AU  - C.
AU  - Lee,
AU  - S-K.
AU  - Marsalis,
AU  - S.
AU  - Gewirtz,
AU  - A.
AU  - H.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s10567-022-00400-9
L1  - internal-pdf://1306966950/Cai-2022-Effectiveness of generationpmto to pr.pdf
PY  - 2022
SP  - No Pagination Specified
T2  - Clinical Child and Family Psychology Review
TI  - Effectiveness of generationpmto to promote parenting and child adjustment: A meta-analytic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-71341-001
UR  - https://link.springer.com/article/10.1007/s10567-022-00400-9
UR  - https://link.springer.com/content/pdf/10.1007/s10567-022-00400-9.pdf
ER  -
TY  - JOUR
AB  - Parental involvement is a key ingredient in school policy and various parental involvement programs aim at raising children&#039;s school success. 

Adding to existing meta-analyses summarizing the findings on the effectiveness of parental involvement programs, we included academic and nonacademic outcomes, and analyzed the correspondence between changes in parents&#039; involvement and changes in children&#039;s outcomes. 

We synthesized findings regarding the effectiveness of parental involvement interventions for children&#039;s academic and nonacademic outcomes from preschool to third grade. A total of 307 effect sizes were obtained from 39 studies included in the meta-analysis. Using a random-effect approach, the average effect suggested that parental involvement interventions had a positive and moderate effect on children&#039;s overall performance, as well as on academic and nonacademic outcomes when considered separately. School-based and home-based interventions were not significantly associated with the overall effect. Further characteristics of the intervention were analyzed as moderators. 

The effects of the intervention on parental involvement itself were significantly associated with the effect size differences on children&#039;s outcomes. Implications for policy and practice are discussed. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
AN  - 35679215
AU  - Cosso,
AU  - J.
AU  - von
AU  - Suchodoletz,
AU  - A.
AU  - Yoshikawa,
AU  - H.
DB  - Alerts 6_2022.enl
DO  - /10.1037/fam0000992
L1  - internal-pdf://0086818312/2022-68974-001.cleaned.pdf
PY  - 2022
SP  - 09
T2  - Journal of Family Psychology
TI  - Effects of parental involvement programs on young children&#039;s academic and social-emotional outcomes: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=35679215
VL  - 09
ER  -
TY  - JOUR
AB  - -
AD  - See, Celine. Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Level 2, Clinical Research Centre, Block MD11, 10 Medical Drive, 117597, Singapore. Electronic address: e0323532@u.nus.edu.Ng, Matthew. Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Level 2, Clinical Research Centre, Block MD11, 10 Medical Drive, 117597, Singapore. Electronic address: e0310260@u.nus.edu.Ignacio, Jeanette. Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Level 2, Clinical Research Centre, Block MD11, 10 Medical Drive, 117597, Singapore. Electronic address: nurimjj@nus.edu.sg.
AN  - 36528945
AU  - See,
AU  - C.
AU  - Ng,
AU  - M.
AU  - Ignacio,
AU  - J.
DA  - Dec 16
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.ienj.2022.101231
DP  - Ovid Technologies
J2  - Int Emerg Nurs
L1  - internal-pdf://2613467027/1-s2.0-S1755599X2200088X-main.cleaned.pdf
LA  - English
M3  - Review
N1  - See, CelineNg, MatthewIgnacio, JeanetteS1755-599X(22)00088-X
PY  - 2022
SP  - 101231
T2  - International emergency nursing
TI  - Effectiveness of music interventions in reducing pain and anxiety of patients in pediatric and adult emergency departments: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36528945
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36528945&amp;id=doi:10.1016%2Fj.ienj.2022.101231&amp;issn=1878-013X&amp;isbn=&amp;volume=66&amp;issue=&amp;spage=101231&amp;pages=101231&amp;date=2022&amp;title=International+emergency+nursing&amp;atitle=Effectiveness+of+music+interventions+in+reducing+pain+and+anxiety+of+patients+in+pediatric+and+adult+emergency+departments%3A+A+systematic+review+and+meta-analysis.&amp;aulast=See&amp;pid=%3Cauthor%3ESee+C%3C%2Fauthor%3E%3CAN%3E36528945%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 66
ER  -
TY  - JOUR
AB  - **BACKGROUND AND OBJECTIVES**
The effects of chronic exercise interventions (CEIs) on core symptoms and executive functions (EFs) of attention-deficit/hyperactivity disorder (ADHD) and how different characteristics of CEIs could modify the effect remain unclear. We synthesized the current evidence on the effects of CEIs on core symptoms and EFs in children and adolescents with ADHD.

**METHODS**
Data sources include PubMed, Embase, Web of Science, Cochrane Library, and China National Knowledge Infrastructure from database inception to July 31, 2022. Study selection includes randomized controlled trials that reported on the effects of CEIs on core symptoms and/or EFs in ADHD aged 6 to 18 years.

**RESULTS**
Twenty-two randomized controlled trials were included. CEIs had a small beneficial effect on overall core symptoms (standardized mean difference [SMD] = -0.39, 95% confidence interval [CI]: -0.64 to -0.14), as well as inattention (SMD = -0.32, 95% CI: -0.63 to -0.004) among children and adolescents with ADHD. Closed-skill exercise showed a large improvement in core symptoms (SMD = -0.83, 95% CI: -1.30 to -0.35), whereas open-skill exercise did not. Additionally, CEIs had a moderately beneficial effect on overall EFs (SMD = -0.68, 95% CI: -0.91 to -0.45) and a moderate-to-large effect on the specific domains of EFs. The pooled effects on overall core symptoms and EFs were not significantly modified by study population (children or adolescents), exercise session duration (&lt;=50 or &gt;50 minutes per session, median), or total exercise sessions (&lt;24 or &gt;=24 sessions, median).

**CONCLUSIONS**
CEIs have small-to-moderate beneficial effects on overall core symptoms and EFs in children and adolescents with ADHD.
AD  - Huang, Huan. School of Exercise and Health.Jin, Zhijuan. Department of Developmental and Behavioral Pediatrics, Shanghai Children&#039;s Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China.He, Changshuang. School of Exercise and Health.Guo, Shaoyu. School of Exercise and Health.Zhang, Yiwen. Department of Developmental and Behavioral Pediatrics, Shanghai Children&#039;s Medical Center, School of Medicine, Shanghai Jiaotong University, Shanghai, China.Quan, Minghui. School of Exercise and Health.Quan, Minghui. Shanghai Frontiers Science Research Base of Exercise and Metabolic Health, Shanghai University of Sport, Shanghai, China; and.
AN  - 36510746
AU  - Huang,
AU  - H.
AU  - Jin,
AU  - Z.
AU  - He,
AU  - C.
AU  - Guo,
AU  - S.
AU  - Zhang,
AU  - Y.
AU  - Quan,
AU  - M.
DA  - Dec 13
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1542/peds.2022-057745
DP  - Ovid Technologies
J2  - Pediatrics
L1  - internal-pdf://0290148916/Huang-2022-Chronic Exercise for Core Symptoms.pdf
LA  - English
N1  - Using Smart Source ParsingDecHuang, HuanJin, ZhijuanHe, ChangshuangGuo, ShaoyuZhang, YiwenQuan, Minghuie2022057745
PY  - 2022
SP  - 13
T2  - Pediatrics
TI  - Chronic Exercise for Core Symptoms and Executive Functions in ADHD: A Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36510746
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:36510746&amp;id=doi:10.1542%2Fpeds.2022-057745&amp;issn=0031-4005&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2022&amp;title=Pediatrics&amp;atitle=Chronic+Exercise+for+Core+Symptoms+and+Executive+Functions+in+ADHD%3A+A+Meta-analysis.&amp;aulast=Huang&amp;pid=%3Cauthor%3EHuang+H%3C%2Fauthor%3E%3CAN%3E36510746%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://watermark.silverchair.com/peds_2022057745.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAsEwggK9BgkqhkiG9w0BBwagggKuMIICqgIBADCCAqMGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMDJF7UU72opEcso5iAgEQgIICdBJZVzdfx0DgbwQqccNiWYgQ354NVSZnVJuumhItS64Vj2UCVhrSPQofhgF4-QSaJu1HyWrQyNAwy9HmH-IJ4AiB0ZrNy4E0LlZeo1vH0tXFmSArKfpHaZAO9VIRZf20aXg1WOK7VuOQn5GD4AoW80JgMZqitMsibQ2vIibL0LNrpaNoGattR-L84DgB3fwXK3lBueNqrjaaTM511bdoetxETSFhVy8Rnp3AqLF-Hb1b476e5B90LdqXOS0G0j1P9gRdmdZ2XzGwOg48p_uL9T7ohmH5JAWfCNTLgM4e6XsHO4P4trg6_C_EorVySMlT3lh64bSyuO2GsmfRo-Ylq9EHlCBQ8kaxog7XV3k9XvVApc2Urh57Y0cAj8nco6Syz9M1OuzkI0Fz5cLAmD5o0g7klQa2xfGDooaYqaIqbeDshzEYn--NXmCFQbfANlWFWeoIXO6zjEw4KuOtKvsOrLK24GTuprD69rzPcuazCIfZYuLuLRJsp4FW8JSvXjy_z8T5_O4fcGqNyMvBBGHPk4SY2k9XAfQ4OrnRdXGD7wOkFqXi8MKR3iTbWncAcMZwy3C0kZepFqIFgkaRIyiQSFxSC6nG_nK-E2uIUgCMkhdjAuPCjTA4RzDqBIY2diYogZ2RUDkijQsREwg31r5lMKqmdmJfzyoLihE9fjpH-ojBl2nHySp0w4vJOvQMon07sTFl91InTJpHx8lTAz52MMxr-x3NfDFuZuxbF2u9ilLRpdXxSHmzOg_FppcuM7JRnf-Zwph7cktxwuRdA0XDnLSCbHP6zXZdX2jhKx8Nqv8dpcaMvLRzwjBHrpqZevIbcn4KPzI
VL  - 13
ER  -
TY  - JOUR
AB  - Siblings of persons with neurodevelopmental conditions (NDCs) have increased risk of poorer psychosocial functioning. This systematic review evaluated quantitative and qualitative evidence on sibling mental health and wellbeing outcomes following psychosocial interventions and the risk and protective factors associated with post-intervention outcomes. From 2025 identified studies published from 1991 to 2022 across ten databases, 24 studies were included. The largest immediate post-intervention improvements were in self-esteem, social wellbeing and knowledge of NDCs. The most sustained improvements in intervention groups at follow-up periods were in emotional and behavioural adjustment and NDC knowledge. There were positive, but small, differences in favour of the intervention groups on knowledge of NDCs, self-esteem, coping and the sibling relationship as compared to waitlist control groups. Psychosocial interventions for siblings are heterogeneous, and more data, including consideration of unique family circumstances, are needed to improve reporting and replicability, to measure effectiveness and tailor necessary supports.
AN  - 36175605
AU  - Wolff,
AU  - B.
AU  - Magiati,
AU  - I.
AU  - Roberts,
AU  - R.
AU  - Skoss,
AU  - R.
AU  - Glasson,
AU  - E.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-022-00413-4
L1  - internal-pdf://3958372503/Wolff-2022-Psychosocial Interventions and Supp.pdf
PY  - 2022
SP  - 30
T2  - Clinical Child &amp; Family Psychology Review
TI  - Psychosocial Interventions and Support Groups for Siblings of Individuals with Neurodevelopmental Conditions: A Mixed Methods Systematic Review of Sibling Self-reported Mental Health and Wellbeing Outcomes
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=36175605
UR  - https://link.springer.com/content/pdf/10.1007/s10567-022-00413-4.pdf
VL  - 30
ER  -
TY  - JOUR
AB  - BAKGRUNN
MITT VALG er en norsk tilpasset versjon av det universelt forebyggende undervisningsprogrammet Lions Quest som er utviklet i USA. MITT VALG er beskrevet som et livsmestringsprogram med fokus på sosial og emosjonell læring, psykisk helse, kritisk tenkning og faglig utvikling. Denne oppsummeringen tar for seg opplæringsprogrammet MITT VALG for ungdomskolen. MITT VALG eies av Stiftelsen Det er mitt valg, opprettet av Lions Norge.

METODE
Denne oppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline, Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

RESULTATER
Resultatene består av en vurdering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. MITT VALG er godt beskrevet og begrunnet, og tiltakseier tilbyr noe implementeringsstøtte. Det er gjennomført &eacute;n norsk effektstudie, men resultatene på de fleste utfallsmål viser ikke effekt av programmet. Studien er mangelfullt rapportert og det er uklart hvilke av utfallsmålene som er mest sentrale for tiltaket effektivitet. MITT VALG har vært under revisjon vår 2020, noe som ytterligere svekker effektstudiens relevans.

KONKLUSJON
MITT VALG klassifiseres på evidensnivå 2 &ndash; Teoretisk begrunnede tiltak.
AU  - Sæle,
AU  - R.
AU  - G.,
AU  - Aasheim,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2021
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Mitt valg! Ungdomsskole-versjonen (1. utg)
UR  - https://ungsinn.no/post_tiltak_arkiv/mitt-valg-ungdomsskole-versjonen-1-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - <b>Objective:</b> We reviewed previously published meta-analyses of neurofeedback applied to children with ADHD and conducted a new meta-analysis of randomized controlled trials (RCTs) that updates previous results and incorporates methodological modifications. <b>Method:</b> Searches were carried out through PubMed, Sage, PsycINFO, SpringerLink, and Psicodoc. We used Hedges&#039; (adjusted) g and a random-effects model. To assess heterogeneity, Q and I&lt;sup&gt;2&lt;/sup&gt; were calculated. We performed different analyses depending on the control groups, ADHD symptoms, pre- and/or posttreament data used and symptom evaluator.
AD  - Riesco-Matias, Pablo. Pontifical University of Salamanca, Spain.Yela-Bernabe, Jose Ramon. Pontifical University of Salamanca, Spain.Crego, Antonio. Pontifical University of Salamanca, Spain.Sanchez-Zaballos, Elena. Pontifical University of Salamanca, Spain.
AN  - 30646779
AU  - Riesco-Matias,
AU  - P.
AU  - Yela-Bernabe,
AU  - J.
AU  - R.
AU  - Crego,
AU  - A.
AU  - Sanchez-Zaballos,
AU  - E.
DA  - 02
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1087054718821731
DP  - Ovid Technologies
J2  - J Atten Disord
KW  - Attention Deficit Disorder with Hyperactivity/th [Therapy]
KW  - *Attention Deficit Disorder with Hyperactivity
KW  - Central Nervous System Stimulants/tu [Therapeutic Use]
KW  - Child
KW  - Humans
KW  - Learning
KW  - *Neurofeedback
KW  - 0 (Central Nervous System Stimulants)
L1  - internal-pdf://1552814281/Riesco-Matias-2021.pdf
LA  - English
M3  - Meta-Analysis
N1  - Riesco-Matias, PabloYela-Bernabe, Jose RamonCrego, AntonioSanchez-Zaballos, Elena
PY  - 2021
SP  - 473-485
T2  - Journal of Attention Disorders
TI  - What Do Meta-Analyses Have to Say About the Efficacy of Neurofeedback Applied to Children With ADHD? Review of Previous Meta-Analyses and a New Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=30646779
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30646779&amp;id=doi:10.1177%2F1087054718821731&amp;issn=1087-0547&amp;isbn=&amp;volume=25&amp;issue=4&amp;spage=473&amp;pages=473-485&amp;date=2021&amp;title=Journal+of+Attention+Disorders&amp;atitle=What+Do+Meta-Analyses+Have+to+Say+About+the+Efficacy+of+Neurofeedback+Applied+to+Children+With+ADHD%3F+Review+of+Previous+Meta-Analyses+and+a+New+Meta-Analysis.&amp;aulast=Riesco-Matias&amp;pid=%3Cauthor%3ERiesco-Matias+P%3C%2Fauthor%3E%3CAN%3E30646779%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1087054718821731
VL  - 25
ER  -
TY  - JOUR
AB  - **Introduction**
Around 250 million children in low-income and middle-income countries are at risk of not fulfilling their developmental potential. There is a need to update syntheses investigating the effects of combined nutrition and stimulation interventions on children&#039;s growth and development and identify intervention characteristics associated with positive effects. 

**Methods**
We did a systematic review to: (1) understand the effects of integrated nutrition and stimulation interventions versus (i) usual care and (ii) standalone nutrition or stimulation interventions, on the growth and development of children under five; (2) explore intervention characteristics (delivery strategies, behaviour change techniques, intensity and personnel) associated with positive effects. We searched eight databases for studies published from inception to 16 November 2020. Eligible studies were randomised and non-randomised controlled trials of integrated nutrition and stimulation interventions examining growth and developmental outcomes. We performed meta-analyses for length-for-age/height-for-age, weight-for-age and weight-for-length/weight-for-height Z scores and cognitive, motor and language development scores, and subgroup analyses by intervention characteristics. We conducted random-effects metaregression to assess potential subgroup differences in outcomes by intervention characteristics. 

**Results**
Twenty trials were included in the meta-analysis. Pooled effect sizes showed significant benefits of integrated interventions on developmental outcomes compared with usual care and standalone nutrition interventions (I-2 &gt;75%) but not on growth outcomes. Moreover, integrated interventions have non-significant effects on developmental outcomes compared with standalone stimulation interventions. Integrated interventions showed greater effects on cognitive (p=0.039) and language (p=0.040) outcomes for undernourished children compared with adequately nourished children. The effects of integrated interventions on developmental outcomes did not differ by intervention characteristics. 

**Conclusion**
Integrated interventions have greater benefits for children&#039;s development than usual care or standalone nutrition interventions, especially in settings with high levels of undernutrition. Future studies should use standardised reporting of implementation processes to identify intervention characteristics linked to positive effects.
AN  - WOS:000691869900005
AU  - Dulal,
AU  - S.
AU  - Prost,
AU  - A.
AU  - Karki,
AU  - S.
AU  - Saville,
AU  - N.
AU  - Merom,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/bmjgh-2020-003872
L1  - internal-pdf://0448180964/Dulal-2021-Characteristics and effects of inte.pdf
PY  - 2021
SP  - 16
T2  - Bmj Global Health
TI  - Characteristics and effects of integrated nutrition and stimulation interventions to improve the nutritional status and development of children under 5 years of age: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000691869900005
UR  - https://gh.bmj.com/content/bmjgh/6/7/e003872.full.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
The influence of childhood trauma on the treatment outcomes of pharmacological and/or psychological interventions for adolescents and adults with bipolar disorder was systematically reviewed.
 
**METHODS**
Randomised and non-randomised studies of interventions for bipolar disorder that included an assessment of childhood trauma were eligible. MEDLINE Complete, Embase, PsycINFO, and the Cochrane Central Register of Controlled Trials were searched. Two independent reviewers completed the screening and extraction process. Two independent reviewers assessed the risk of bias in the included studies using the Cochrane Collaboration&#039;s Risk of Bias tool and the Newcastle-Ottawa Scale. Alongside a narrative synthesis, random-effects meta-analyses were performed. 

**RESULTS**
 Twelve studies (1175 participants) were included. The narrative review highlighted differential treatment outcomes among individuals with a history of childhood trauma. The meta-analyses suggested that childhood trauma was unrelated to treatment response (five studies, 426 participants; odds ratio 0.58, 95% CI 0.27-1.25, p = .164) but may be associated with greater improvement in global functioning (three studies, 210 participants; Hedge&#039;s g 0.65, 95% CI 0.04-1.26, p = .037). *

**LIMITATIONS**
The impact of childhood trauma on the effectiveness of specific pharmacological/psychological interventions could not be explored due to the small body of research identified. 

**CONCLUSION**
 The overall quality of the extant evidence is low, which precludes definitive comment on the role of childhood trauma in the treatment of bipolar disorder. Additional research that uses large and representative samples is required to ascertain whether a history of childhood trauma affects the treatment outcomes of interventions for individuals with bipolar disorder.
AN  - 34606813
AU  - Wrobel,
AU  - A.
AU  - L.
AU  - Jayasinghe,
AU  - A.
AU  - Russell,
AU  - S.
AU  - E.
AU  - Marx,
AU  - W.
AU  - Alameda,
AU  - L.
AU  - Dean,
AU  - O.
AU  - M.
AU  - Cotton,
AU  - S.
AU  - M.
AU  - Berk,
AU  - M.
AU  - Turner,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2021.09.103
L1  - internal-pdf://2925121537/Wrobel-2021-The influence of childhood trauma.pdf
PY  - 2021
SP  - 350-362
T2  - Journal of Affective Disorders
TI  - The influence of childhood trauma on the treatment outcomes of pharmacological and/or psychological interventions for adolescents and adults with bipolar disorder: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34606813
VL  - 296
ER  -
TY  - JOUR
AB  - BACKGROUND: 
This study aimed to assess the efficacy of acupuncture for treating attention deficit hyperactivity disorder (ADHD) in children and adolescents.

PATIENTS AND METHODS: 
Systematic review and meta-analysis including randomized controlled trials that compared the effects of acupuncture treatment (AT) with pharmacotherapy (methylphenidate hydrochloride, MPH) among patients with ADHD. A total of 12 electronic databases were searched from inception until February 3, 2020. The main outcomes were the effective rate and post-treatment hyperactivity scores. We also assessed the incidence of adverse events and follow-up course.

RESULTS: 
A total of 10 studies involving 876 patients were included in this study. The meta-analysis revealed that AT yielded a significantly higher effective rate than MPH (odds ratio 2.239, 95% CI 1.438-3.487, p &lt; 0.001, 8 studies), and that AT can reduce the hyperactivity scores to a lesser degree than MPH (standardized mean difference = -0.882, 95% CI -1.295 to -0.469, p &lt; 0.001, 3 studies). Two studies reported no adverse events in the AT group, while one study suggested that AT can reduce adverse drug reactions. Furthermore, 3 studies concluded that the effects of AT were maintained, even after completion of treatment.

CONCLUSION: 
This study suggests that AT may be more beneficial than MPH therapy for ADHD patients. However, the evidence may be highly limited, especially considering the outcome of hyperactivity scores with the high risk of bias, very low GRADE, and small number of studies. Thus, further studies of rigorous design and high quality are needed to confirm and strengthen the results, especially in the Western part of the world. Additionally, well-designed randomized controlled trials that evaluate adverse events and include a long-term follow-up should be conducted to determine the efficacy, safety, and side effects of AT for ADHD in children and adolescents.
AD  - Chen, Yi-Chen. Department of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.Chen, Yi-Chen. School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien, Taiwan.Chen, Yi-Chen. Department of Education and Human Potentials Development, National Dong Hwa University, Hualien, Taiwan.Wu, Li-Kung. Department of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.Wu, Li-Kung. School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien, Taiwan.Lee, Ming-Shinn. Department of Education and Human Potentials Development, National Dong Hwa University, Hualien, Taiwan.Kung, Yen-Lun. Department of Chinese Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, kung818@gmail.com.Kung, Yen-Lun. School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien, Taiwan, kung818@gmail.com.
AN  - 33508834
AU  - Chen,
AU  - Y.
AU  - C.
AU  - Wu,
AU  - L.
AU  - K.
AU  - Lee,
AU  - M.
AU  - S.
AU  - Kung,
AU  - Y.
AU  - L.
DA  - Jan 28
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1159/000513655
DP  - Ovid Technologies
J2  - Complementary Med
L1  - internal-pdf://1535744780/Chen-2021.pdf
LA  - English
M3  - Meta-Analysis
N1  - Chen, Yi-ChenWu, Li-KungLee, Ming-ShinnKung, Yen-Lun
PY  - 2021
SP  - 1-11
T2  - Complementary Medical Research
TI  - The Efficacy of Acupuncture Treatment for Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33508834
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33508834&amp;id=doi:10.1159%2F000513655&amp;issn=2504-2092&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-11&amp;date=2021&amp;title=Complementary+Medical+Research&amp;atitle=Die+Wirksamkeit+der+Akupunktur+in+der+Behandlung+der+Aufmerksamkeitsdefizit-Hyperaktivitatsstorung%3A+Eine+systematische+Ubersicht+und+Metaanalyse.&amp;aulast=Chen&amp;pid=%3Cauthor%3EChen+YC%3C%2Fauthor%3E%3CAN%3E33508834%3C%2FAN%3E%3CDT%3EMeta-Analysis%3C%2FDT%3E
UR  - https://www.karger.com/Article/Abstract/513655
UR  - https://www.karger.com/Article/Pdf/513655
ER  -
TY  - JOUR
AB  - In recent years, the application of virtual reality (VR) for therapeutic purposes has escalated dramatically. Favorable properties of VR for engaging patients with autism, in particular, have motivated an enormous body of investigations targeting autism-related disabilities with this technology. This study aims to provide a comprehensive meta-analysis for evaluating the effectiveness of VR on the rehabilitation and training of individuals diagnosed with an autism spectrum disorder. Accordingly, we conducted a systematic search of related databases and, after screening for inclusion criteria, reviewed 33 studies for more detailed analysis. Results revealed that individuals undergoing VR training have remarkable improvements with a relatively large effect size with Hedges g of 0.74. Furthermore, the results of the analysis of different skills indicated diverse effectiveness. The strongest effect was observed for daily living skills (g = 1.15). This effect was moderate for other skills: g = 0.45 for cognitive skills, g = 0.46 for emotion regulation and recognition skills, and g = 0.69 for social and communication skills. Moreover, five studies that had used augmented reality also showed promising efficacy (g = 0.92) that calls for more research on this tool. In conclusion, the application of VR-based settings in clinical practice is highly encouraged, although their standardization and customization need more research.
AN  - WOS:000670292500001
AU  - Karami,
AU  - B.
AU  - Koushki,
AU  - R.
AU  - Arabgol,
AU  - F.
AU  - Rahmani,
AU  - M.
AU  - Vahabie,
AU  - A.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2021.665326
L1  - internal-pdf://1414311403/Karami-2021-Effectiveness of Virtual_Augmented.pdf
PY  - 2021
SP  - 25
T2  - Frontiers in Psychiatry
TI  - Effectiveness of Virtual/Augmented Reality-Based Therapeutic Interventions on Individuals With Autism Spectrum Disorder: A Comprehensive Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000670292500001
VL  - 12
ER  -
TY  - JOUR
AB  - The impact of trauma on children and youth has potentially serious and long-lasting negative consequences, including increased involvement in the juvenile and criminal justice systems. 

The objective of this study was to meta-analyze research on the effectiveness of trauma-informed treatment programs for justice-involved youth and youth at risk of justice system involvement who have experienced some form of trauma. 

Our systematic search identified 29 publications that met our eligibility criteria and represent 30 treatment-comparison contrasts. Six of these evaluated the effectiveness of trauma-informed programs for justice-involved youth, and the remaining 24 evaluated programs for at-risk children and youth. 

The findings suggest that cognitive-behavioral therapy (CBT), including trauma-focused CBT, is effective. In addition, there was weak evidence suggesting that programs that used a cognitive restructuring component or had the participant create a trauma narrative were slightly more effective than programs without these features. Additional high-quality randomized controlled trials are needed.

(PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-69816-005
AU  - Olaghere,
AU  - A.
AU  - Wilson,
AU  - D.
AU  - B.
AU  - Kimbrell,
AU  - C.
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/00938548211003117
L1  - internal-pdf://0006892834/Olaghere-2021-Trauma-informed interventions fo.pdf
PY  - 2021
SP  - 1261-1277
T2  - Criminal Justice and Behavior
TI  - Trauma-informed interventions for at-risk and justice-involved youth: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-69816-005
UR  - https://journals.sagepub.com/doi/10.1177/00938548211003117
UR  - https://journals.sagepub.com/doi/pdf/10.1177/00938548211003117
VL  - 48
ER  -
TY  - JOUR
AB  - Resilience may be defined as the ability to recover and adapt to adverse situations. Given that resilience involves cognitive and behavioral aspects, it could be promoted based on strategies that favor them, especially during childhood and adolescence. As a result, several resilience-focused programs have been developed and studied.
 
This systematic review of Randomized Controlled Trials (RCTs) aimed to assess resilience-focused programs for children (&lt;12 years old) and adolescents (12-22 years old) compared to active (treatment as usual, other program modalities, and educational curriculum at school) or inactive (waiting list, no treatment) control groups. We performed a systematic review of meta-analyses of RCTs. 

The following databases were searched: Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Embase, and PsycINFO. Two authors independently selected the studies, extracted the data, and assessed the studies&#039; risk of bias. Meta-analyses of random effects were conducted to calculate the standard mean differences (SMD) and 95% confidence interval (CI) of program effectiveness. 

Of the 17 RCTs that met the inclusion criteria, 13 provided sufficient data to assess the effectiveness of the programs after their implementation. Meta-analyses indicated overall effectiveness of the programs in promoting resilience (SMD = 0.48, 95% CI [0.15, 0.81], p = 0.0077). The subgroup analysis indicated effectiveness only among adolescents&#039; resilience (SMD = 0.48, 95% CI [0.08, 0.88], p = 0.02). The follow-up analysis also indicated evidence of continuation of results within a period of up to 6 months up (SMD = 0.12, 95% CI [-0.44, 0.69], p = 0.02). 

These results indicated the effectiveness of promoting resilience, especially in adolescents, and its continuation in follow-up analyses. These findings are promising in the field of resilience programs; however, further studies are necessary to analyze the different possible characteristics of programs and their results. <b>Clinical Trial Registration:</b> [https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020179874], [CRD42020179874].
AN  - 34880812
AU  - Pinto,
AU  - T.
AU  - M.
AU  - Laurence,
AU  - P.
AU  - G.
AU  - Macedo,
AU  - C.
AU  - R.
AU  - Macedo,
AU  - E.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyg.2021.754115
L1  - internal-pdf://2852335381/Pinto-2021-Resilience Programs for Children an.pdf
PY  - 2021
SP  - 754115
T2  - Frontiers in Psychology
TI  - Resilience Programs for Children and Adolescents: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34880812
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645691/pdf/fpsyg-12-754115.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Neonatal abstinence syndrome (NAS) due to opioid withdrawal may result in disruption of the mother-infant relationship, sleep-wake abnormalities, feeding difficulties, weight loss, seizures and neurodevelopmental problems. OBJECTIVES: To assess the effectiveness and safety of using a sedative versus control (placebo, usual treatment or non-pharmacological treatment) for NAS due to withdrawal from opioids and determine which type of sedative is most effective and safe for NAS due to withdrawal from opioids. SEARCH METHODS: We ran an updated search on 17 September 2020 in CENTRAL via CRS Web and MEDLINE via Ovid. We searched clinical trials databases, conference proceedings and the reference lists of retrieved articles for randomised controlled trials and quasi-randomised trials. 

**SELECTION CRITERIA**: We included trials enrolling infants with NAS born to mothers with an opioid dependence with more than 80% follow-up and using randomised, quasi-randomised and cluster-randomised allocation to sedative or control. 

**DATA COLLECTION AND ANALYSIS**: Three&nbsp;review authors assessed trial eligibility and risk of bias, and independently extracted data. We used the GRADE approach to assess the certainty of the evidence. 

**MAIN RESULTS**: We included 10 trials (581 infants) with NAS secondary to maternal opioid use in pregnancy. There were multiple comparisons of different sedatives and regimens. There were limited data available for use in sensitivity analysis of studies at low risk of bias. Phenobarbital versus supportive care:&nbsp;one study reported there may be little or no&nbsp;difference in treatment failure with phenobarbital and supportive care versus supportive care alone (risk ratio (RR) 2.73, 95% confidence interval (CI) 0.94 to 7.94; 62 participants; very low-certainty evidence). No infant had a clinical seizure. The study did not report mortality, neurodevelopmental disability and adverse events. There may be&nbsp;an increase in days&#039; hospitalisation and treatment from use of phenobarbital (hospitalisation: mean difference (MD) 20.80, 95% CI 13.64 to 27.96; treatment: MD 17.90, 95% CI 11.98 to 23.82; both 62 participants; very low-certainty evidence). Phenobarbital versus diazepam:&nbsp;there may be a&nbsp;reduction in treatment failure with phenobarbital versus diazepam (RR 0.39, 95% CI 0.24 to 0.62; 139 participants; 2 studies; low-certainty evidence). The studies did not report mortality, neurodevelopmental disability and adverse events. One study reported there may be little or no&nbsp;difference in days&#039; hospitalisation and treatment (hospitalisation: MD 3.89, 95% CI -1.20 to 8.98; 32 participants; treatment: MD 4.30, 95% CI -0.73 to 9.33; 31 participants; both low-certainty evidence). Phenobarbital versus chlorpromazine: there may be a reduction in treatment failure with phenobarbital versus chlorpromazine (RR 0.55, 95% CI 0.33 to 0.92; 138 participants; 2 studies;&nbsp;very low-certainty evidence), and no infant had a seizure. The studies did not report mortality and neurodevelopmental disability. One study reported there may be little or no difference in days&#039; hospitalisation (MD 7.00, 95% CI -3.51 to 17.51; 87 participants; low-certainty evidence) and 0/100 infants had an adverse event. Phenobarbital and opioid versus opioid alone: one study reported no infants with treatment failure and no clinical seizures in either group (low-certainty evidence). The study did not report mortality, neurodevelopmental disability and adverse events.&nbsp;One study reported there may be a reduction in&nbsp;days&#039; hospitalisation for infants treated with phenobarbital and opioid (MD -43.50, 95% CI -59.18 to -27.82; 20 participants; low-certainty evidence). Clonidine and opioid versus opioid alone: one study reported there may be little or no difference in treatment failure with clonidine and dilute tincture of opium (DTO) versus DTO alone (RR 0.09, 95% CI 0.01 to 1.59; 80 participants; very low-certainty evidence). All five infants with treatment failure were in the DTO group. There may be little or&nbsp;no difference in seizures (RR 0.14, 95% CI 0.01 to 2.68; 80 participants; very low-certainty evidence). All three infants with seizures were in the DTO group. There may be little or&nbsp;no difference in mortality after discharge (RR 7.00, 95% CI 0.37 to 131.28; 80 participants; very low-certainty evidence). All three deaths were in the clonidine and DTO group. The study did not report neurodevelopmental disability. There may be little or no difference in days&#039; treatment (MD -4.00, 95% CI -8.33 to 0.33; 80 participants; very low-certainty evidence). One adverse event occurred in the clonidine and DTO group. There may be little or no difference in rebound NAS after stopping treatment, although all seven cases&nbsp;were in the clonidine and DTO group. Clonidine and opioid versus phenobarbital and opioid: there may be little or no difference in treatment failure (RR 2.27, 95% CI 0.98 to 5.25; 2 studies, 93 participants; very low-certainty evidence). One study reported one infant in the clonidine and morphine group had a seizure, and there were no infant mortalities. The studies did not report neurodevelopmental disability. There may be&nbsp;an increase in days&#039; hospitalisation and days&#039; treatment with clonidine and opioid versus phenobarbital and opioid(hospitalisation: MD 7.13, 95% CI 6.38 to 7.88; treatment: MD 7.57, 95% CI 3.97 to 11.17; both 2 studies, 91 participants; low-certainty evidence). There may be little or&nbsp;no difference in adverse events (RR 1.55, 95% CI 0.44 to 5.40; 2 studies, 93 participants; very low-certainty evidence). However, there was oversedation only in the phenobarbital and morphine group;&nbsp;and hypotension, rebound hypertension and rebound NAS only in the clonidine and morphine group. 

**AUTHORS&#039; CONCLUSIONS**: There is very low-certainty evidence that phenobarbital increases duration of hospitalisation and treatment, but reduces days to regain birthweight and duration of supportive care each day compared to supportive care alone. There is low-certainty evidence that phenobarbital reduces treatment failure compared to diazepam and very low-certainty evidence that&nbsp;&nbsp;phenobarbital reduces treatment failure compared to chlorpromazine. There is low-certainty evidence of an increase in days&#039; hospitalisation and days&#039; treatment with clonidine and opioid compared to phenobarbital and opioid. There are insufficient data to determine the safety and incidence of adverse events for infants treated with combinations of opioids and sedatives including phenobarbital and clonidine.
AD  - Department of Neonatal Medicine, RPA Women and Babies, Royal Prince Alfred Hospital, Camperdown, Australia.Central Clinical School, School of Medicine, The University of Sydney, Sydney, Australia.
AN  - 34002380
AU  - Zankl,
AU  - A.
AU  - Martin,
AU  - J.
AU  - Davey,
AU  - J.
AU  - G.
AU  - Osborn,
AU  - D.
AU  - A.
DA  - May 18
DB  - My EndNote Library.enl
DO  - 10.1002/14651858.CD002053.pub4
DP  - NLM
J2  - The Cochrane database of systematic reviews
KW  - Bias
KW  - Chlorpromazine/therapeutic use
KW  - Clonidine/therapeutic use
KW  - Diazepam/therapeutic use
KW  - Humans
KW  - Hypnotics and Sedatives/*therapeutic use
KW  - Infant, Newborn
KW  - Narcotics/therapeutic use
KW  - Neonatal Abstinence Syndrome/*drug therapy
KW  - Opioid-Related Disorders/*drug therapy
KW  - Phenobarbital/therapeutic use
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
LA  - eng
N1  - 1469-493xZankl, AngelikaMartin, JillDavey, Jane GOsborn, David AJournal ArticleMeta-AnalysisResearch Support, Non-U.S. Gov&#039;tSystematic ReviewCochrane Database Syst Rev. 2021 May 18;5(5):CD002053. doi: 10.1002/14651858.CD002053.pub4.
PY  - 2021
SP  - Cd002053
T2  - Cochrane Database Syst Rev
TI  - Sedatives for opioid withdrawal in newborn infants
VL  - 5
ER  -
TY  - JOUR
AB  - BACKGROUND: Digital health interventions (DHIs) are efficacious for several mental disorders in youth; however, integrated, evidence-based knowledge about the mechanisms of change in these interventions is lacking. 

OBJECTIVE: This systematic review aims to comprehensively evaluate studies on mediators and mechanisms of change in different DHIs for common mental disorders in children and adolescents. 

METHODS: A systematic literature search of the electronic databases Cochrane Central Register of Controlled Trials, Embase, MEDLINE, and PsycINFO was conducted, complemented by backward and forward searches. Two independent reviewers selected studies for inclusion, extracted the data, and rated the methodological quality of eligible studies (ie, risk of bias and 8 quality criteria for process research). 

RESULTS: A total of 25 studies that have evaluated 39 potential mediators were included in this review. Cognitive mediators were the largest group of examined intervening variables, followed by a broad range of emotional and affective, interpersonal, parenting behavior, and other mediators. The mediator categories with the highest percentages of significant intervening variables were the groups of affective mediators (4/4, 100%) and combined cognitive mediators (13/19, 68%). Although more than three-quarters of the eligible studies met 5 or more quality criteria, causal conclusions have been widely precluded. 

CONCLUSIONS: The findings of this review might guide the empirically informed advancement of DHIs, contributing to improved intervention outcomes, and the discussion of methodological recommendations for process research might facilitate mediation studies with more pertinent designs, allowing for conclusions with higher causal certainty in the future.
AN  - 34842543
AU  - Domhardt,
AU  - M.
AU  - Engler,
AU  - S.
AU  - Nowak,
AU  - H.
AU  - Lutsch,
AU  - A.
AU  - Baumel,
AU  - A.
AU  - Baumeister,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/29742
L1  - internal-pdf://1650436129/Domhardt-2021.pdf
PY  - 2021
SP  - e29742
T2  - Journal of Medical Internet Research
TI  - Mechanisms of Change in Digital Health Interventions for Mental Disorders in Youth: Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34842543
VL  - 23
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Mindfulness-Based Interventions (MBIs) have been increasingly proposed as treatment in patients with Attention-Deficit/Hyperactivity Disorder (ADHD), showing promising results on different proposed outcomes, in both children and adults. 

**OBJECTIVES**: To systematically review and meta-analyse studies concerning the effects of MBIs on either ADHD and associated features, associated clinical conditions, neurocognitive impairments, mindfulness skills, global functioning and quality of life. 

**METHODS**: Searches were conducted on five databases, including controlled and observational studies on both adults and children populations. The review process was compliant to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Meta-analyses and meta-regression models were conducted. 

**RESULTS**: Thirty-one full-texts were included. In both adults and children, MBIs showed to be more effective than waiting lists in improving ADHD symptoms and some other outcomes. In adults, a medium pooled effect size was shown by meta-analysis for ADHD symptoms but in some cases a publication bias was detected. Subgroup analysis and meta-regression confirmed the gap detected by our systematic review between the medium/large effect size of inactive-controlled studies and the low/negligible one of active-controlled studies. In children, no active-controlled studies have been conducted. Mindfulness Awareness Practice (MAP) and Mindfulness Based Cognitive Therapy (MBCT) were the most used protocols in adult studies, whereas a combination of MBCT and Mindfulness Based Stress Reduction (MBSR) was more preferred for children and adolescent patients. 

**CONCLUSIONS**: Even if further studies with a better methodology are needed, we can suggest the MBIs may be useful as complementation and not as replacement of other active interventions.
AN  - 34146899
AU  - Oliva,
AU  - F.
AU  - Malandrone,
AU  - F.
AU  - di
AU  - Girolamo,
AU  - G.
AU  - Mirabella,
AU  - S.
AU  - Colombi,
AU  - N.
AU  - Carletto,
AU  - S.
AU  - Ostacoli,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2021.05.068
L1  - internal-pdf://0992461859/Oliva-2021-The efficacy of mindfulness-based i.pdf
PY  - 2021
SP  - 475-486
T2  - Journal of Affective Disorders
TI  - The efficacy of mindfulness-based interventions in attention-deficit/hyperactivity disorder beyond core symptoms: A systematic review, meta-analysis, and meta-regression
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34146899
VL  - 292
ER  -
TY  - JOUR
AB  - A systematic review and meta-analysis conducted to evaluate the combined effect of distraction intervention for needle-related pain in order to provide the basis for developing an effective nursing intervention for children. 

We searched three electronic databases, PubMed, Embase, and CINAHL, for original articles published in the period from 1 January 2011 to 31 July 2019. In addition, a manual search was performed on the basis of references in the literature and the references of the articles in pursuit of comprehensive data until 10 December 2019. 

Meta-analysis was performed by the synthesis of the effect size, homogeneity, heterogeneity, and trim-and-fill method using MIX 2.0 Pro. Well-planned RCTs, single-center studies, high-quality studies, participants older than 10 years of age, and visual and clown distraction interventions were effective for needle-related pain and distress management among children. 

The results showed evidence supporting the effect of distraction interventions for children&#039;s needle-related pain and distress. Through this review, strategies were identified to design better interventions to improve the outcomes. 

Copyright &copy; 2021 by the authors. Licensee MDPI, Basel, Switzerland.
AN  - 2013582925
AU  - Cho,
AU  - M.
AU  - K.
AU  - Choi,
AU  - M.
AU  - Y.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/ijerph18179159
L1  - internal-pdf://2923437988/Cho-2021-Effect of distraction intervention fo.pdf
PY  - 2021
T2  - International Journal of Environmental Research and Public Health
TI  - Effect of distraction intervention for needle-related pain and distress in children: A systematic review and meta-analysis
UR  - https://www.mdpi.com/1660-4601/18/17/9159/pdf
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-18-09159/article_deploy/ijerph-18-09159.pdf
VL  - 18(17) (no pagination)
ER  -
TY  - JOUR
AB  - Sammanfattning
Bakgrund och syfte
I den h&auml;r rapporten utv&auml;rderar vi program f&ouml;r att f&ouml;rebygga psykisk oh&auml;lsa hos barn upp till 18 års ålder. Med program avser vi standardiserade manualbaserade insatser som syftar till att påverka ett beteende eller ett tillstånd. Rapporten t&auml;cker program som f&ouml;rmedlas till barnet sj&auml;lvt i skolan eller som ges till f&ouml;r&auml;ldrarna eller hela familjen.

Vi har avgr&auml;nsat psykisk oh&auml;lsa till dels utagerande dels inåtv&auml;nda problem och beteenden. Till utagerande beteenden h&ouml;r aggressivitet och st&ouml;rande uppf&ouml;rande. Vi avgr&auml;nsade inåtv&auml;nda problem till ångest och depressivitet. Kortsiktiga mål f&ouml;r den h&auml;r typen av program &auml;r att minska nivån av problem på gruppnivå. Långsiktiga mål &auml;r att f&ouml;rebygga svåra problem och diagnoser som normbrytande beteenden, uppf&ouml;randest&ouml;rning, ångest och depression och att minska risken f&ouml;r långsiktiga konsekvenser av psykisk oh&auml;lsa som till exempel kriminalitet, våld och suicid.

F&ouml;r att ett program skulle ses som f&ouml;rebyggande kr&auml;vde vi att effekterna f&ouml;ljdes upp efter minst sex månader, i enlighet med internationella riktlinjer.

F&ouml;rebyggande program kan ges på flera nivåer. Universella program f&ouml;rmedlas brett, till exempel till hela skolor medan selektiva program erbjuds till grupper av barn som på gruppnivå har en f&ouml;rh&ouml;jd risk f&ouml;r psykisk oh&auml;lsa. Indikerade program ges riktat till barn som visar tidiga tecken på psykisk oh&auml;lsa. Studier d&auml;r barnen uppfyllde kriterier på en diagnos och d&auml;r målet var att snabbt få en f&ouml;rb&auml;ttring, det vill s&auml;ga snarast behandling, ingick inte i utv&auml;rderingen.

Syftet med projektet var att uppdatera en tidigare SBU-rapport från år 2010 om program f&ouml;r att f&ouml;rebygga psykisk oh&auml;lsa hos barn. Uppdateringen &auml;r en del av ett regeringsuppdrag om psykisk h&auml;lsa bland barn och unga (S2020/01043/FS). Rapporten består av systematiska &ouml;versikter om programmens effekter och risker, de erfarenheter som finns av programmen och deras kostnadseffektivitet samt en diskussion om etiska och sociala aspekter på anv&auml;ndningen av program.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2021
TI  - Program f&ouml;r att f&ouml;rebygga suicid och suicidf&ouml;rs&ouml;k hos barn: En systematisk &ouml;versikt med utv&auml;rdering av effekter och h&auml;lsoekonomiska aspekter
UR  - https://www.sbu.se/sv/publikationer/SBU-utvarderar/program-for-att-forebygga-suicid-och-suicidforsok-hos-barn/
ER  -
TY  - JOUR
AB  - **Background**: Adolescents use heroin as well as prescription opioids. Unfortunately, access to care for adolescents and young adults with opioid use disorder is limited. Naltrexone is a mu opioid receptor antagonist which blocks the effects of opioids, prevents intoxication and physiologic dependence. Here, we present literature on the use of naltrexone for adolescents with opioid use disorder. 

**Method(s)**: Electronic databases were searched for scientific literature addressing the use of naltrexone in adolescents with opioid use disorder. 

**Result(s)**: Four scientific articles were found to meet inclusion criteria. A retrospective case-series review in Australian hospitals suggests less overdose events after the implantation of extended-release naltrexone pellets. A case series utilizing extended-release naltrexone injection at a community treatment center found 10 of 16 patients remained in treatment for 4 or more months, 9 of 16 had a &quot;good outcome.&quot; Two retrospective cohort studies assessing insurance data found significantly improved retention rates for youth receiving naltrexone compared to behavioral services alone. 

**Conclusion(s)**: Preliminary data suggest improved risk of overdose events, retention in treatment, and improved outcomes with the use of extended-release naltrexone for youth struggling with opioid use disorder. Copyright &copy; 2021 Taylor &amp; Francis Group, LLC.
AN  - 2012853377
AU  - LaCasse,
AU  - M.
AU  - Quigley,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/14659891.2021.1941351
L1  - internal-pdf://0128365605/LaCasse-2021-Naltrexone for adolescent opioid.pdf
PY  - 2021
T2  - Journal of Substance Use.
TI  - Naltrexone for adolescent opioid use disorder: a bridge in the treatment gap?
UR  - http://www.tandfonline.com/loi/ijsu20
UR  - https://www.tandfonline.com/doi/full/10.1080/14659891.2021.1941351
UR  - https://www.tandfonline.com/doi/pdf/10.1080/14659891.2021.1941351?needAccess=true
ER  -
TY  - JOUR
AB  - **Purpose**: Adolescent mental illness often goes undetected. Youth and teen Mental Health First Aid (MHFA) are variations of adult MHFA that aims to help adults and adolescents recognize the signs and provide help where appropriate. 

We conducted a systematic review to summarize the current evidence for youth and teen MHFA, providing direction for future training and research. Method(s): A systematic search was performed on September 12, 2020 on PubMed, Embase, PsycINFO, ERIC, and 
Cochrane using keywords related to teen or youth MHFA, adolescents, and mental health. A narrative synthesis was then carried out. 

**Result(s)**: Of the 695 articles identified, 14 studies were included. All studies were from the U.S. and Australia. All studies demonstrated significant improvements in knowledge, recognition, stigmatizing attitudes, confidence, helping intentions, and helping behavior in both adult and youth participants. Improvement in knowledge and confidence was most reported, and improvement in helping behavior was the least reported. There is encouraging evidence of long-term benefits after the training. 

**Conclusion(s)**: More studies need to be conducted in non-Western countries, high-risk populations, and different professional settings. Future interventions could also consider different modes of learning, longer-term follow-up, and the measurement of outcomes that evaluate the quality of helping behavior. Copyright &copy; 2020 Society for Adolescent Health and Medicine
AN  - 2010052875
AU  - Ng,
AU  - S.
AU  - H.
AU  - Tan,
AU  - N.
AU  - J.
AU  - H.
AU  - Luo,
AU  - Y.
AU  - Goh,
AU  - W.
AU  - S.
AU  - Ho,
AU  - R.
AU  - Ho,
AU  - C.
AU  - S.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jadohealth.2020.10.018
L1  - internal-pdf://3344744944/Ng-2021-A Systematic Review of Youth and Teen.pdf
PY  - 2021
SP  - 199-210
T2  - Journal of Adolescent Health
TI  - A Systematic Review of Youth and Teen Mental Health First Aid: Improving Adolescent Mental Health
UR  - http://www.elsevier.com/locate/jadohea
UR  - https://www.jahonline.org/article/S1054-139X(20)30632-7/fulltext
VL  - 69
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis examined the effectiveness of parent-infant interventions for parents of preterm infants on parental sensitivity compared to standard care or active comparators. This review follows the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and was prospectively registered in the International Prospective Register of Systematic Reviews (PROSPERO; registration ID: CRD42016047083). Database searches were performed from inception to 2020 to identify eligible randomized controlled trials. Two review authors independently selected studies, extracted data, and assessed the risk of bias using the Cochrane risk of bias assessment tool and quality of evidence using the Grades of Recommendation, Assessment, Development and Evaluation (GRADE) guidelines. A total of 19 studies (n = 2,111 participants) were included and 14 were suitable to be pooled in our primary outcome meta-analysis. Results show no significant effect of parent-infant interventions over standard care or basic educational programs, on parental sensitivity. Results may not necessarily be due to the ineffectiveness of the interventions but rather due to implementation failure or high risk of bias of included studies.
AN  - WOS:000620010100001
AU  - Lavallee,
AU  - A.
AU  - De
AU  - Clifford-Faugere,
AU  - G.
AU  - Ballard,
AU  - A.
AU  - Aita,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1053815121991928
L1  - internal-pdf://0860585653/Lavallee.pdf
PY  - 2021
T2  - JOURNAL OF EARLY INTERVENTION
TI  - Parent-Infant Interventions to Promote Parental Sensitivity During NICU Hospitalization: Systematic Review and Meta-Analysis
UR  - https://journals.sagepub.com/doi/10.1177/1053815121991928
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1053815121991928
ER  -
TY  - JOUR
AB  - **OBJECTIVES**: Prescribing antipsychotic medications to children and adolescents with severe mental and developmental disorders is common; however, there is a lack of consensus on appropriate metabolic monitoring for this population. This review systematically evaluates studies examining metabolic monitoring of children and adolescents prescribed antipsychotic medication to understand the clinical practice of metabolic monitoring and identify opportunities to improve the safety of antipsychotic prescribing in this population.

**METHODS**: A systematic search for original research on metabolic monitoring in children and adolescents prescribed antipsychotics was conducted in six databases (PubMed, EMBASE, PsycINFO, The Cochrane Library [Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, CENTRAL], Cochrane Methodology Register and Web of Science [Science and Social Science Citation Index]) from inception to February 2020 following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies were assessed for quality and findings summarised using narrative synthesis.

**RESULTS**: Fifteen papers were identified. Studies agreed on the need for metabolic monitoring; however, there was a gap between guideline-recommended practice and clinical practice. Variable rates of baseline and subsequent monitoring were reported for both physical and biochemical parameters, with particularly low rates for monitoring requiring venesection. Younger age was also associated with lower monitoring rates. Implementation of quality improvement activities (new guidelines, staff education and checklists) improved monitoring rates although the measurement of biochemical parameters still occurred in only a minority of children.

**CONCLUSION**: Despite widespread awareness and concern regarding metabolic side-effects, monitoring occurred inconsistently and infrequently, particularly for biochemical parameters requiring venesection. Monitoring of anthropometric measures (weight, body mass index and waist circumference) with escalation to more laboratory testing where metabolic concerns are identified may improve monitoring. Minimising iatrogenic harm, through reduced antipsychotic prescription where possible, is a clinical priority in this population.
AD  - Mead, Laura. Metro North Mental Health, Royal Brisbane and Women&#039;s Hospital, Herston, QLD, Australia.Mead, Laura. Children&#039;s Health Queensland Hospital and Health Service, South Brisbane, QLD, Australia.Ayres, Alice. Children&#039;s Health Queensland Hospital and Health Service, South Brisbane, QLD, Australia.Blake, Julie A. Metro North Mental Health, Royal Brisbane and Women&#039;s Hospital, Herston, QLD, Australia.Blake, Julie A. QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.Scott, James G. Metro North Mental Health, Royal Brisbane and Women&#039;s Hospital, Herston, QLD, Australia.Scott, James G. QIMR Berghofer Medical Research Institute, Herston, QLD, Australia.Scott, James G. Queensland Centre for Mental Health Research, Wacol, QLD, Australia.
AN  - 33951933
AU  - Mead,
AU  - L.
AU  - Ayres,
AU  - A.
AU  - Blake,
AU  - J.
AU  - A.
AU  - Scott,
AU  - J.
AU  - G.
DA  - May 05
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/00048674211009620
DP  - Ovid Technologies
J2  - Aust N Z J Psychiatry
L1  - internal-pdf://2398228290/Mead-2021.pdf
LA  - English
N1  - Mead, LauraAyres, AliceBlake, Julie AScott, James G
PY  - 2021
SP  - 48674211009620
T2  - Australian &amp; New Zealand Journal of Psychiatry
TI  - Monitoring of metabolic side-effects in children and adolescents prescribed antipsychotic medication: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33951933
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33951933&amp;id=doi:10.1177%2F00048674211009620&amp;issn=0004-8674&amp;isbn=&amp;volume=&amp;issue=&amp;spage=48674211009620&amp;pages=48674211009620&amp;date=2021&amp;title=Australian+%26+New+Zealand+Journal+of+Psychiatry&amp;atitle=Monitoring+of+metabolic+side-effects+in+children+and+adolescents+prescribed+antipsychotic+medication%3A+A+systematic+review.&amp;aulast=Mead&amp;pid=%3Cauthor%3EMead+L%3C%2Fauthor%3E%3CAN%3E33951933%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/10.1177/00048674211009620
UR  - https://journals.sagepub.com/doi/pdf/10.1177/00048674211009620
ER  -
TY  - JOUR
AB  - In families where child abuse and neglect have already occurred, there is a strong imperative to provide interventions that reduce or eliminate harm done to children. Parenting programs lack tailoring for the needs of maltreating parents, and maltreating parents themselves are a heterogeneous group with varying needs. The literature on the effectiveness of parenting interventions for high-risk parents is limited, and this scarcity of knowledge can result in child protection cases being treated as a natural experiment. For children who experience ongoing maltreatment by their parents, the most stringent test for effectiveness goes beyond an improvement in positive parenting skills-child abuse and neglect must reduce or be eliminated. The present review addressed the research question What evidence is there that parenting interventions conducted with parents who maltreat their children, reduce the incidence of further child maltreatment? Databases were searched for trials of parenting interventions where participants were maltreating parents and outcome data included an objective measure of child abuse and neglect. Nine studies satisfied the selection criteria and are summarized. Four studies reported a statistically significant difference between groups in favor of the intervention group for two parenting interventions, Parent-Child Interaction Therapy and SafeCare. However, the review concludes that none of the reviewed parenting interventions have been demonstrated to be effective at reducing all types of child maltreatment through a high-quality RCT. Previous research is compromised by several critical methodological limitations, including low participant recruitment and retention, and narrow selection criteria. Recommendations are offered for future research on parenting interventions that aim to reduce child abuse and neglect. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Whitcombe-Dobbs, Sarah: sarah.whitcombe-dobbs@canterbury.ac.nzWhitcombe-Dobbs, Sarah: School of Health Sciences, University of Canterbury, Christchurch, New Zealand, 8140, sarah.whitcombe-dobbs@canterbury.ac.nzWhitcombe-Dobbs, Sarah: University of Canterbury, Christchurch, New ZealandTarren-Sweeney, Michael: University of Canterbury, Christchurch, New Zealand
AN  - 2020-69171-006
AU  - Whitcombe-Dobbs,
AU  - Sarah
AU  - Tarren-Sweeney,
AU  - Michael
DA  - Februar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/2516103219893383
DP  - Ovid Technologies
KW  - child abuse and neglect, child maltreatment recidivism, high-risk families, parenting intervention effectiveness, treatment evaluation
KW  - *Child Abuse
KW  - *Child Neglect
KW  - *Family
KW  - *Intervention
KW  - *Parenting
KW  - Parents
KW  - Recidivism
KW  - Treatment
KW  - Group Intervention
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human
L1  - internal-pdf://1734196632/Whitcombe-Dobbs-2019.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2021
SP  - 374-393
T2  - Developmental Child Welfare
TI  - What evidence is there that parenting interventions reduce child abuse and neglect among maltreating families? A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-69171-006
UR  - https://journals.sagepub.com/doi/10.1177/2516103219893383
UR  - https://journals.sagepub.com/doi/pdf/10.1177/2516103219893383
VL  - 1
ER  -
TY  - JOUR
AB  - **Introduction**: The aims of this systematic review and meta-analysis are to provide a summary of the current literature concerning compulsory treatments in patients with eating disorders (ED) and to understand whether compulsorily and involuntarily treated patients differ in terms of baseline characteristics and treatment outcomes. 

**Method(s)**: Relevant articles were identified following the PRISMA guidelines by searching the following terms: &quot;treatment refusal&quot;, &quot;forced feeding&quot;, &quot;compulsory/coercive/involuntary/forced treatment/admission&quot;, &quot;eating disorders&quot;, &quot;feeding and eating disorders&quot;, &quot;anorexia nervosa&quot;, &quot;bulimia nervosa&quot;. Research was restricted to articles concerning humans and published between 1975 and 2020 in English. 

**Result(s)**: Out of 905 articles retrieved, nine were included for the analyses allowing the comparisons between 242 compulsorily and 738 voluntarily treated patients. Mean body mass index (BMI) was slightly lower in patients compelled to treatments. Mean illness duration, BMI at discharge and BMI variation showed no significant differences between the two groups. Average length of hospitalization was 3 weeks longer among compulsory-treated patients, but this did not result in a higher increase in BMI. No significant risk difference on mortality was estimated (three studies). 

**Conclusion(s)**: Compulsory treatments are usually intended for patients having worse baseline conditions than voluntary ones. Those patients are unlikely to engage in treatments without being compelled but, after the treatments, albeit with longer hospitalisations, they do achieve similar outcomes. Therefore, we can conclude that forcing patients to treatment is a conceivable option. Level of Evidence: Level I, systematic review and meta-analysis. Copyright &copy; 2020, The Author(s).
AN  - 2007059027
AU  - Atti,
AU  - A.
AU  - R.
AU  - Mastellari,
AU  - T.
AU  - Valente,
AU  - S.
AU  - Speciani,
AU  - M.
AU  - Panariello,
AU  - F.
AU  - De
AU  - Ronchi,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40519-020-01031-1
L1  - internal-pdf://2010598780/Atti-2021-Compulsory treatments in eating diso.pdf
PY  - 2021
SP  - 1037-1048
T2  - Eating and Weight Disorders
TI  - Compulsory treatments in eating disorders: a systematic review and meta-analysis
UR  - http://link.springer.com/journal/40519
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062396/pdf/40519_2020_Article_1031.pdf
VL  - 26
ER  -
TY  - JOUR
AB  - <b>Purpose:</b> Technology-assisted interventions are essential in supporting cancer survivors&#039; psychosocial outcomes, especially for childhood, adolescent, and young adult (AYA) cancer survivors, a tech-savvy generation. This study aims to systematically evaluate review and meta-analyze technology-assisted interventions for childhood and AYA cancer survivors. 

<b>Methods:</b> Following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines, the study team used a pre-set of key words and searched studies across 11 electronic databases and 4 professional websites, and conducted a manual search of reference lists from published reviews. Meta-analysis of small sample size corrected Hedges&#039; g was conducted using meta-regression with robust variance estimation. 

<b>Results:</b> Final analysis included a total of 28 clinical trials, including 237 effect sizes reported an overall statistically significant treatment effect of technology-assisted psychosocial interventions for childhood and AYA cancer survivors, g = 0.382, 95% confidence interval (CI) 0.243 to 0.521, p &lt; 0.0001. Subgroup analysis revealed that distraction-based interventions and interventions for psychosocial and emotional health were overall statistically significant, whereas interventions for childhood and AYA cancer survivors&#039; cancer knowledge outcomes and physical and functional health outcomes were statistically nonsignificant. Moderator analysis found intervention target was a significant moderator. 

<b>Conclusions:</b> Technology-assisted interventions for childhood and AYA cancer survivors were overall effective across domains of survivorship outcomes. Favorable evidence was found primarily for childhood cancer survivors with limited support for AYA cancer survivors. 

<b>Implications for Cancer Survivors:</b> Although existing technology-assisted interventions are overall promising, research support for cancer survivors from different age groups and with different psychosocial challenges varies and should be considered individually.
AD  - Zhang, Anao. University of Michigan School of Social Work, Ann Arbor, Michigan, USA.Zebrack, Bradley. University of Michigan School of Social Work, Ann Arbor, Michigan, USA.Acquati, Chiara. University of Houston Graduate College of Social Work; and The University of Texas MD Anderson Cancer Center Department of Health Disparities Research, Houston, Texas, USA.Roth, Michael. Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.Levin, Nina Jackson. University of Michigan School of Social Work, and Department of Anthropology, Ann Arbor, Michigan, USA.Wang, Kaipeng. Graduate School of Social Work, University of Denver, Denver, Colorado, USA.Schwartz, Samantha. University of Michigan School of Social Work, Ann Arbor, Michigan, USA.
AN  - 33960845
AU  - Zhang,
AU  - A.
AU  - Zebrack,
AU  - B.
AU  - Acquati,
AU  - C.
AU  - Roth,
AU  - M.
AU  - Levin,
AU  - N.
AU  - J.
AU  - Wang,
AU  - K.
AU  - Schwartz,
AU  - S.
DA  - May 06
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1089/jayao.2021.0012
DP  - Ovid Technologies
J2  - J Adolesc Young Adult Oncol
L1  - internal-pdf://3886420856/Zhang-2021.pdf
LA  - English
N1  - Using Smart Source ParsingMayZhang, AnaoZebrack, BradleyAcquati, ChiaraRoth, MichaelLevin, Nina JacksonWang, KaipengSchwartz, Samantha
PY  - 2021
SP  - 06
T2  - Journal of Adolescent &amp; Young Adult Oncology
TI  - Technology-Assisted Psychosocial Interventions for Childhood, Adolescent, and Young Adult Cancer Survivors: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33960845
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33960845&amp;id=doi:10.1089%2Fjayao.2021.0012&amp;issn=2156-5333&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+Adolescent+%26+Young+Adult+Oncology&amp;atitle=Technology-Assisted+Psychosocial+Interventions+for+Childhood%2C+Adolescent%2C+and+Young+Adult+Cancer+Survivors%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Zhang&amp;pid=%3Cauthor%3EZhang+A%3C%2Fauthor%3E%3CAN%3E33960845%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.liebertpub.com/doi/pdfplus/10.1089/jayao.2021.0012
VL  - 06
ER  -
TY  - JOUR
AB  - Chronic stress is associated with dysregulations in the physiological stress system, resulting in diverse negative developmental outcomes. Since adolescence is a period characterized by increased stress-sensitivity, and schools are an important environment for the developing adolescent, school-based interventions promoting psychosocial functioning are of particular interest to prevent adverse outcomes. The present study therefore aimed to investigate the effectiveness of such interventions on hypothalamic pituitary adrenal-axis (i.e., cortisol) and cardiovascular (i.e., blood pressure [BP] and heart rate [HR]/heart rate variability [HRV]) parameters of stress in adolescents, and examined moderators of effectiveness. The search resulted in the inclusion of k = 9 studies for cortisol, k = 16 studies for BP, and k = 20 studies for HR/HRV. The results indicated a significant small overall effect on reducing BP, but no significant effect for HR/HRV. For cortisol, large methodological variation in the few primary studies did not allow for quantitative analyses, but a qualitative review demonstrated inconsistent results. For BP and HR/HRV, larger effects were observed for intervention programs with a mindfulness and/or meditation component, for interventions without a cognitive-behavioural component and for interventions with a higher intensity. Providing adolescents with techniques to improve indicators of physiological stress may prevent emerging mental health problems.
AN  - WOS:000678820400001
AU  - Loon,
AU  - A.
AU  - W.
AU  - G.
AU  - Creemers,
AU  - H.
AU  - E.
AU  - Okorn,
AU  - A.
AU  - Vogelaar,
AU  - S.
AU  - Miers,
AU  - A.
AU  - C.
AU  - Saab,
AU  - N.
AU  - Westenberg,
AU  - P.
AU  - M.
AU  - Asscher,
AU  - J.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/smi.3081
L1  - internal-pdf://2993534895/Loon-The effects of school-based interventions.pdf
PY  - 2021
SP  - 23
T2  - Stress and Health
TI  - The effects of school-based interventions on physiological stress in adolescents: A meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000678820400001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/smi.3081?download=true
ER  -
TY  - JOUR
AB  - The preschool years presents an important opportunity to support children&#039;s social and emotional development. Social and emotional learning (SEL) programs in early childhood education and care (ECEC) have gained an increased interest due to its potential to improve child health and educational outcomes. 

We aimed to identify existing systematic reviews on universal, curriculum-based SEL interventions in ECEC settings (children aged 0 to 7 years), assess their risk of bias, synthesize the findings and identify knowledge gaps. We undertook a systematic literature search in seven different databases. Reviews of studies without control groups were excluded. Each abstract and full text article was assessed independently, and disagreements were solved in consensus. Relevant reviews were assessed for bias using the ROBIS tool. 

Of 4912 records identified through database searches, two systematic reviews met the inclusion criteria. Both reviews were assessed as having a high risk of bias. The results were used to summarize existing knowledge and knowledge gaps. In conclusion, SEL interventions in preschool settings must be considered knowledge gaps. There is a need for more high-quality primary studies and further systematic reviews that adhere to strict scientific methods and address the overwhelming heterogeneity in field, in terms of interventions, settings and outcomes.</p>
AN  - WOS:000711916200001
AU  - Djamnezhad,
AU  - D.
AU  - Koltcheva,
AU  - N.
AU  - Dizdarevic,
AU  - A.
AU  - Mujezinovic,
AU  - A.
AU  - Peixoto,
AU  - C.
AU  - Coelho,
AU  - V.
AU  - Achten,
AU  - M.
AU  - Kolumban,
AU  - E.
AU  - Machado,
AU  - F.
AU  - Hofvander,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/feduc.2021.691670
L1  - internal-pdf://3751614639/feduc-06-691670.cleaned.pdf
PY  - 2021
SP  - 11
T2  - Frontiers in Education
TI  - Social and Emotional Learning in Preschool Settings: A Systematic Map of Systematic Reviews
UR  - &lt;Go to ISI&gt;://WOS:000711916200001
VL  - 6
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
There has been a burgeoning development of trauma-informed care (TIC) interventions for children involved with the child welfare system. A quantitative synthesis of these interventions&#039; effects on child wellbeing is warranted for the advancement of evidence-based practices. 

**OBJECTIVES: **
We conducted a systematic review and meta-analysis to estimate TIC interventions&#039; pooled effect on the wellbeing of children involved with the child welfare system, while examining factors that may moderate the effect.

**METHODS: **
The search and review yielded 15 eligible studies. We first estimated the interventions&#039; pooled effect based on a compound child wellbeing indicator, and then on three specific child wellbeing indicators: posttraumatic stress disorder (PTSD) symptom reduction, behavioral problem reduction, and other psychological wellbeing improvement. We further conducted subgroup meta-analyses to evaluate factors that may moderate the effect. 

**RESULTS: **
TIC interventions had a moderate effect as shown through the compound child wellbeing indicator (SMD = 0.47, 95% CI = [0.27, 0.67]) as well as the three specific indicators (SMD = 0.37 to 0.52, 95% CI = [0.02, 0.88]). Subgroup meta-analyses indicated that the intervention effects varied but generally remained at a moderate level across study and intervention characteristics. 

**CONCLUSIONS: **
The findings suggest that TIC interventions for children involved with the child welfare system are promising, but the effect may vary by intervention strategies and other factors. Implications for practices and research are discussed.
AN  - 34478999
AU  - Zhang,
AU  - S.
AU  - Conner,
AU  - A.
AU  - Lim,
AU  - Y.
AU  - Lefmann,
AU  - T.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.chiabu.2021.105296
L1  - internal-pdf://3648274992/Zhang-2021-Trauma-informed care for children i.pdf
PY  - 2021
SP  - 105296
T2  - Child Abuse &amp; Neglect
TI  - Trauma-informed care for children involved with the child welfare system: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34478999
VL  - 122
ER  -
TY  - JOUR
AB  - Prodromal symptoms of Autism Spectrum Disorder (ASD) have been detected within the first year of life. This review evaluated evidence from randomized controlled trials (RCTs) of parent-mediated interventions for infants under 24 months who are at risk for ASD. Electronic databases, including grey literature, were searched up till November 2019. Seven RCTs were identified. There was substantial heterogeneity in recruitment, outcome measures and effect size calculations. Interventions did not reduce the risk of later ASD diagnosis and post-intervention effects on infant outcomes were inconsistent, with five studies reporting significant improvements across both treatment and control groups. Moderate level of evidence of intervention effects on parental interaction skills and the small number of RCTs, and significant limitations restrict generalizability across studies.
AN  - WOS:000670844900005
AU  - Law,
AU  - M.
AU  - L.
AU  - Singh,
AU  - J.
AU  - Mastroianni,
AU  - M.
AU  - Santosh,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-021-05148-9
L1  - internal-pdf://1892005182/Law-Parent-Mediated Interventions for Infants.pdf
PY  - 2021
SP  - 22
T2  - Journal of Autism and Developmental Disorders
TI  - Parent-Mediated Interventions for Infants under 24 Months at Risk for Autism Spectrum Disorder: A Systematic Review of Randomized Controlled Trials
UR  - &lt;Go to ISI&gt;://WOS:000670844900005
UR  - https://link.springer.com/content/pdf/10.1007/s10803-021-05148-9.pdf
ER  -
TY  - JOUR
AB  - **Objectives**
 Polypharmacy is common in maintenance treatment of bipolar illness, but proof of greater efficacy compared to monotherapy is assumed rather than well known. We systematically reviewed the evidence from the literature to provide recommendations for clinical management and future research. 

**Method(s)**
 A systematic review was conducted on the use of polypharmacy in bipolar prophylaxis. Relevant papers published in English through 31 December 2019 were identified searching the electronic databases MEDLINE, Embase, PsycINFO, and the Cochrane Library. 

**Result(s)**
Twelve studies matched inclusion criteria, including 10 randomized controlled trials (RCTs). The best drug combination in prevention is represented by lithium + valproic acid which showed a significant effect on time to mood relapses (HR = 0.57) compared to valproic acid monotherapy, especially for manic episodes (HR = 0.51). The effect was significant in terms of time to new drug treatment (HR = 0.51) and time to hospitalization (HR = 0.57). A significant reduction in the frequency of mood relapses was also reported for lithium + valproic acid vs. lithium monotherapy (RR=0.12); however, the trial had a small sample size. Lamotrigine + valproic acid reported significant efficacy in prevention of depressive episodes compared to lamotrigine alone. 

**Conclusion(s)** The literature to support a generally greater efficacy with polypharmacy in bipolar illness is scant and heterogeneous. Within that limited evidence base, the best drug combination in bipolar prevention is represented by lithium + valproic acid for manic, but not depressive episodes. Clinical practice should focus more on adequate monotherapy before considering polypharmacy. Copyright &copy; 2021 The Authors. Acta Psychiatrica Scandinavica published by John Wiley &amp; Sons Ltd.
AN  - 2011605935
AU  - Amerio,
AU  - A.
AU  - Russo,
AU  - D.
AU  - Miletto,
AU  - N.
AU  - Aguglia,
AU  - A.
AU  - Costanza,
AU  - A.
AU  - Benatti,
AU  - B.
AU  - Odone,
AU  - A.
AU  - Barroilhet,
AU  - S.
AU  - A.
AU  - Brakoulias,
AU  - V.
AU  - Dell&#039;Osso,
AU  - B.
AU  - Serafini,
AU  - G.
AU  - Amore,
AU  - M.
AU  - Ghaemi,
AU  - S.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/acps.13312
L1  - internal-pdf://3342577998/Amerio-2021-Polypharmacy as maintenance treatm.pdf
PY  - 2021
SP  - 259-276
T2  - Acta Psychiatrica Scandinavica
TI  - Polypharmacy as maintenance treatment in bipolar illness: A systematic review
UR  - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1600-0447
UR  - https://onlinelibrary.wiley.com/doi/10.1111/acps.13312
VL  - 144(3)
ER  -
TY  - JOUR
AB  - **Purpose:** 
Developmental and life course criminology (DLCC) engages not only in correlational longitudinal research but also in programs of developmental prevention. Within this context, child training on social skills plays an important role. The present article contains a comprehensive meta-analysis of randomized controlled trials (RCTs) on the effects of this type of intervention. 

**Method:** 
We updated a meta-analysis on this topic Losel &amp; Beelman (Annals of the American Academy of Political and Social Science 587:84-109, 2003) to cover more recent studies while focusing specifically on aggression, delinquency, and related antisocial outcomes. From a systematic search of 1133 reports, we found 113 studies with 130 eligible RCT comparisons between a program and control group. Overall, 31,114 children and youths were included in these evaluations. Most interventions were based on a cognitive-behavioral approach. 

**Results:** 
Overall, the mean effect was positive, but rather small (d = 0.25 using the random effect model). There were similar effects on aggression, delinquency, and other outcomes, but a tendency to somewhat stronger effects in behavior observations and official records than in rating scales. Most outcome measurements were assessed within 3 months or up to 1 year after training. Only a minority (k = 14) had follow-up assessments after more than 1 year. In the latter studies, mean effects were no longer significant. Indicated prevention for youngsters who already showed some antisocial behavior had better effects than universal approaches and (partially related to this) older youngsters benefited more than preschool children. There was much heterogeneity in the findings. Evaluations performed since our previous meta-analysis in 2003 did not reveal larger effects, but training format, intensity, and other moderators were relevant. 

**Conclusions:** 
Mean results are promising, but more long-term evaluations, replications, booster approaches, and combinations with other types of interventions are necessary to ensure a substantial impact on antisocial development in the life course. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AU  - Beelmann,
AU  - A.
AU  - Losel,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40865-020-00142-8
L1  - internal-pdf://1699089738/A comprehensive meta-analysis of randomiz-2021.pdf
PY  - 2021
SP  - 41-65
T2  - Journal of Developmental and Life Course Criminology
TI  - A comprehensive meta-analysis of randomized evaluations of the effect of child social skills training on antisocial development
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2021-35706-003
UR  - https://link.springer.com/content/pdf/10.1007/s40865-020-00142-8.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - Problematic Internet use (PIU) can lead to dysfunction and undesired consequences, especially in adolescents and youths. Preventive interventions can reduce them, but should be built on sound evidence. This review synthesizes the available evidence on the effectiveness of primary prevention programs for PIU in adolescents and youths. It adds to previous reviews by broadening the search to general and specific problematic behavior. 

Two independent reviewers performed a systematic search for published studies on PIU and internet addiction in English, French and Spanish using PubMed, PsycINFO, Cochrane Register of Controlled Trials, and Scopus. Published experimental and quasi-experimental studies that assessed the effectiveness of primary prevention programs targeting PIU behaviors were considered for inclusion. Full texts for eligible studies were retrieved and assessed for quality. Five studies were retained for narrative synthesis. Three of them based the intervention strategy on an underlying theory, one on media literacy, and one used an educational-based approach. A meta-analysis showed that all five interventions were effective in preventing internet addiction separately. However, when using the Hartung-KnappSidik-Jonkman (HKSJ) estimator and removing one of the studies because of a disproportionate Hedges&#039; g, combined effects were no longer significant. Although PIU is a popular topic little is known about ways to prevent it. 

This review demonstrates that prevention programs can be based on different theoretical approaches, but that the available evidence is too heterogeneous to derive generalizable conclusions concerning their effectiveness.
AN  - WOS:000644682500010
AU  - Saletti,
AU  - S.
AU  - M.
AU  - R.
AU  - Van
AU  - den
AU  - Broucke,
AU  - S.
AU  - Chau,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.5817/CP2021-2-10
L1  - internal-pdf://2979430538/Saletti-2021.pdf
PY  - 2021
T2  - CYBERPSYCHOLOGY-JOURNAL OF PSYCHOSOCIAL RESEARCH ON CYBERSPACE
TI  - The Effectiveness of Prevention Programs for Problematic Internet Use in Adolescents and Youths: A Systematic Review and Meta-Analysis
UR  - https://cyberpsychology.eu/article/download/13570/11999
VL  - 15
ER  -
TY  - JOUR
AB  - There has been a growing interest in the gastrointestinal system and its significance for autism spectrum disorder (ASD), including the significance of adopting a gluten-free and casein-free (GFCF) diet. The objective was to investigate beneficial and safety of a GFCF diet among children with a diagnosis of ASD. 

We performed a systematic literature search in Medline, Embase, Cinahl, and the Cochrane Library up to January 2020 for existing systematic reviews and individual randomized controlled trials (RCTs). Studies were included if they investigated a GFCF diet compared to a regular diet in children aged 3 to 17 years diagnosed with ASD, with or without comorbidities. The quality of the identified existing reviews was assessed using A Measurement Tool to Assess Systematic Reviews (AMSTAR). The risk of bias in RCTs was assessed using the Cochrane Risk of Bias Tool, and overall quality of evidence was evaluated using Grades of Recommendation, Assessment, Development, and Evaluation (GRADE). We identified six relevant RCTs, which included 143 participants. 

The results from a random effect model showed no effect of a GFCF diet on clinician-reported autism core symptoms (standardized mean difference (SMD) -0.31 (95% Cl. -0.89, 0.27)), parent-reported functional level (mean difference (MD) 0.61 (95% Cl -5.92, 7.14)) or behavioral difficulties (MD 0.80 (95% Cl -6.56, 10.16)). On the contrary, a GFCF diet might trigger gastrointestinal adverse effects (relative risk (RR) 2.33 (95% Cl 0.69, 7.90)). The quality of evidence ranged from low to very low due to serious risk of bias, serious risk of inconsistency, and serious risk of imprecision. Clinical implications of the present findings may be careful consideration of introducing a GFCF diet to children with ASD. However, the limitations of the current literature hinder the possibility of drawing any solid conclusion, and more high-quality RCTs are needed. The protocol is registered at the Danish Health Authority website. Copyright &copy; 2021 by the authors. Licensee MDPI, Basel, Switzerland.
AD  - (Keller) Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen 1014, Denmark (Rimestad) Institute of Psychology, Aarhus University, Aarhus 8000, Denmark (Rohde, Korfitsen, Tarp, Handel) The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg 2000, Denmark (Rohde, Petersen, Korfitsen, Tarp, Handel) The Danish Health Authority, Copenhagen 2300, Denmark (Lauritsen) Psychiatry, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University, Aalborg 9000, DenmarkA. Keller, Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen 1014, Denmark. E-mail: amelie.keller@sund.ku.dk
AN  - 2005917675
AU  - Keller,
AU  - A.
AU  - Rimestad,
AU  - M.
AU  - L.
AU  - Rohde,
AU  - J.
AU  - F.
AU  - Petersen,
AU  - B.
AU  - H.
AU  - Korfitsen,
AU  - C.
AU  - B.
AU  - Tarp,
AU  - S.
AU  - Lauritsen,
AU  - M.
AU  - B.
AU  - Handel,
AU  - M.
AU  - N.
DA  - February
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/nu13020470
DP  - Ovid Technologies
KW  - Autism spectrum disorder
KW  - Childhood
KW  - Gluten-free/casein-free diet
KW  - A Measurement Tool to Assess Systematic Reviews
KW  - adolescent
KW  - autism
KW  - child
KW  - Cinahl
KW  - Cochrane Library
KW  - comorbidity
KW  - controlled study
KW  - drawing
KW  - Embase
KW  - female
KW  - gluten free casein free diet
KW  - human
KW  - male
KW  - Medline
KW  - randomized controlled trial (topic)
KW  - review
KW  - risk assessment
KW  - risk factor
KW  - systematic review
L1  - internal-pdf://2513482614/Keller-2021-The effect of a combined gluten-an.pdf
LA  - English
M3  - Review
PY  - 2021
SP  - 1-18
T2  - Nutrients
TI  - The effect of a combined gluten-and casein-free diet on children and adolescents with autism spectrum disorders: A systematic review and meta-analysis
UR  - https://www.mdpi.com/2072-6643/13/2/470/pdf
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2005917675
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.3390%2Fnu13020470&amp;issn=2072-6643&amp;isbn=&amp;volume=13&amp;issue=2&amp;spage=1&amp;pages=1-18&amp;date=2021&amp;title=Nutrients&amp;atitle=The+effect+of+a+combined+gluten-and+casein-free+diet+on+children+and+adolescents+with+autism+spectrum+disorders%3A+A+systematic+review+and+meta-analysis&amp;aulast=Keller&amp;pid=%3Cauthor%3EKeller+A.%3C%2Fauthor%3E%3CAN%3E2005917675%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://res.mdpi.com/d_attachment/nutrients/nutrients-13-00470/article_deploy/nutrients-13-00470.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - **Innledning**
Betegnelsen psykose eller psykotisk episode er en beskrivelse av en psykisk tilstand hvor personen har vanskeligheter med å skille mellom hva som er virkelig eller ikke.  Antipsykotika benyttes i dag som den fremste behandlingen av psykose, inkludert førstegangspsykose. Studier som omhandler bruk av antipsykotika, er i hovedsak utført på personer med flere tidligere psykoser og ikke personer med førstegangspsykose. Langtidsbehandling med antipsykotika for personer med førstegangspsykoser er vanlig, men både langtids- og korttidseffektene for denne gruppen er uavklarte. Personer med førstegangspsykose er ofte yngre, har ikke mottatt behandling tidligere og kan være mer utsatt for bivirkninger av medikamentell behandling. Det stilles derfor spørsmål ved om det finnes andre og bedre behandlingsmuligheter enn med antipsykotika.

**Hensikt**
Hensikten med denne systematiske oversikten var å undersøke effekten av antipsykotika sammenlignet med placebo eller ikke-medikamentelle tiltak hos personer med førstegangspsykose.

**Metode**
Vi har utarbeidet en systematisk oversikt ved hjelp av fremgangsmåter som beskrevet i Folkehelseinstituttets metodebok for oppsummert forskning og i en fagfellevurdert prosjektplan. For å identifisere relevante studier søkte en bibliotekar seks internasjonale litteraturdatabaser, slik som MEDLINE, EMBASE og PsycINFO, i juni 2021. Vi brukte også &laquo;knowledge graph&raquo; i MAG (Microsoft Academic Graph) til å identifisere ytterligere relevante studier. Vi sjekket referanselistene til alle studier som ble lest i fulltekst, samt studier som hadde tilgrensende tematikk. Vi inkluderte randomiserte kontrollerte studier som undersøkte effekten av antipsykotika sammenlignet med placebo eller ikke-medikamentelle tiltak hos personer med førstegangspsykose. Relevante utfall var:
Psykosesymptomer målt med overordnede kartleggingsverktøy slik som Positive and Negative Syndrome Scale (PANSS) eller Brief Psychiatric Rating Scale (BPRS)
Tilbakefall målt slik studieforfatterne definerte det eller som forverring av psykisk tilstand som krevde behandling.
Funksjonsendring i sosiale relasjoner eller arbeid/utdanning
To medarbeidere valgte uavhengig av hverandre ut relevante studier og vurderte deretter risiko for systematiske skjevheter i de inkluderte studiene. Dette ble gjort ved bruk av sjekklisten Cochrane risk of bias tool 2.0 (RoB 2). Videre hentet to medarbeidere ut relevant data og oppsummerte resultatene i tekst og tabeller. Vi beregnet effektestimater for relevante utfall rapportert i de inkluderte studiene og utførte en meta-analyse på tvers av to studier. Vi beskrev majoriteten av resultatene fra hver enkelt studie for seg, da det ikke var mulig å sammenstille dem i metaanalyser. Vi vurderte tillit til resultatene ved hjelp av GRADE-tilnærmingen (Grading of Recommendations Assessment, Development and Evaluation).

**Resultater**
Litteratursøket resulterte i 4283 referanser (etter dublettkontroll) pluss 802 referanser identifisert via MAG. Vi inkluderte tre RCTer i denne systematiske oversikten, &eacute;n fra Australia og to fra Storbritannia. Studiene var publisert i henholdvis 2018 og 2020. Alle studiene sammenlignet antipsykotika med kognitiv atferdsterapi eller andre psykososiale tiltak, hvor to studier inkluderte en tredje sammenligningsgruppe med kombinasjonstiltak. Studiene hadde relativt få deltakere (&lt;100) som i hovedsak var ungdom eller unge voksne. Alle deltakerne mottok &laquo;tidlige intervensjoner for psykose&raquo; enten som en del av barne- og ungdomspsykiatrien eller spesialisert psykisk helsetjeneste, intervensjonen fant derfor sted i disse settingene. Studiene målte psykosesymptomer og sosial fungering, i tillegg til andre utfall som ikke var relevant for vår problemstilling. Ingen av studiene målte tilbakefall.
AU  - Jardim,
AU  - Patricia
AU  - Sofia
AU  - JacobsenBorge,
AU  - T.
AU  - C.
AU  - Johansen,
AU  - T.
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2021
TI  - Effekten av antipsykotika ved førstegangspsykose:en systematisk oversikt
UR  - https://www.fhi.no/publ/2021/effekten-av-antipsykotika-ved-forstegangspsykose/
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Small-quantity (SQ) lipid-based nutrient supplements (LNSs) provide many nutrients needed for brain development. 

**OBJECTIVES: **
We aimed to generate pooled estimates of the effect of SQ-LNSs on developmental outcomes (language, social-emotional, motor, and executive function), and to identify study-level and individual-level modifiers of these effects. 

**METHODS: **
We conducted a 2-stage meta-analysis of individual participant data from 14 intervention against control group comparisons in 13 randomized trials of SQ-LNSs provided to children age 6-24 mo (total n = 30,024). 

**RESULTS: **
In 11-13 intervention against control group comparisons (n = 23,588-24,561), SQ-LNSs increased mean language (mean difference: 0.07 SD; 95% CI: 0.04, 0.10 SD), social-emotional (0.08; 0.05, 0.11 SD), and motor scores (0.08; 95% CI: 0.05, 0.11 SD) and reduced the prevalence of children in the lowest decile of these scores by 16% (prevalence ratio: 0.84; 95% CI: 0.76, 0.92), 19% (0.81; 95% CI: 0.74, 0.89), and 16% (0.84; 95% CI: 0.76, 0.92), respectively. SQ-LNSs also increased the prevalence of children walking without support at 12 mo by 9% (1.09; 95% CI: 1.05, 1.14). Effects of SQ-LNSs on language, social-emotional, and motor outcomes were larger among study populations with a higher stunting burden (&gt;=35%) (mean difference: 0.11-0.13 SD; 8-9 comparisons). At the individual level, greater effects of SQ-LNSs were found on language among children who were acutely malnourished (mean difference: 0.31) at baseline; on language (0.12), motor (0.11), and executive function (0.06) among children in households with lower socioeconomic status; and on motor development among later-born children (0.11), children of older mothers (0.10), and children of mothers with lower education (0.11). 

**CONCLUSIONS: **
Child SQ-LNSs can be expected to result in modest developmental gains, which would be analogous to 1-1.5 IQ points on an IQ test, particularly in populations with a high child stunting burden. Certain groups of children who experience higher-risk environments have greater potential to benefit from SQ-LNSs in developmental outcomes. 

This trial was registered at www.crd.york.ac.uk/PROSPERO as CRD42020159971.
AN  - 34590116
AU  - Prado,
AU  - E.
AU  - L.
AU  - Arnold,
AU  - C.
AU  - D.
AU  - Wessells,
AU  - K.
AU  - R.
AU  - Stewart,
AU  - C.
AU  - P.
AU  - Abbeddou,
AU  - S.
AU  - Adu-Afarwuah,
AU  - S.
AU  - Arnold,
AU  - B.
AU  - F.
AU  - Ashorn,
AU  - U.
AU  - Ashorn,
AU  - P.
AU  - Becquey,
AU  - E.
AU  - Brown,
AU  - K.
AU  - H.
AU  - Chandna,
AU  - J.
AU  - Christian,
AU  - P.
AU  - Dentz,
AU  - H.
AU  - N.
AU  - Dulience,
AU  - S.
AU  - J.
AU  - L.
AU  - Fernald,
AU  - L.
AU  - C.
AU  - H.
AU  - Galasso,
AU  - E.
AU  - Hallamaa,
AU  - L.
AU  - Hess,
AU  - S.
AU  - Y.
AU  - Huybregts,
AU  - L.
AU  - Iannotti,
AU  - L.
AU  - L.
AU  - Jimenez,
AU  - E.
AU  - Y.
AU  - Kohl,
AU  - P.
AU  - Lartey,
AU  - A.
AU  - Le
AU  - Port,
AU  - A.
AU  - Luby,
AU  - S.
AU  - P.
AU  - Maleta,
AU  - K.
AU  - Matchado,
AU  - A.
AU  - Matias,
AU  - S.
AU  - L.
AU  - Mridha,
AU  - M.
AU  - K.
AU  - Ntozini,
AU  - R.
AU  - Null,
AU  - C.
AU  - Ocansey,
AU  - M.
AU  - E.
AU  - Parvez,
AU  - S.
AU  - M.
AU  - Phuka,
AU  - J.
AU  - Pickering,
AU  - A.
AU  - J.
AU  - Prendergast,
AU  - A.
AU  - J.
AU  - Shamim,
AU  - A.
AU  - A.
AU  - Siddiqui,
AU  - Z.
AU  - Tofail,
AU  - F.
AU  - Weber,
AU  - A.
AU  - M.
AU  - Wu,
AU  - L.
AU  - S.
AU  - F.
AU  - Dewey,
AU  - K.
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1093/ajcn/nqab277
L1  - internal-pdf://1094201469/Prado-2021-Small-quantity lipid-based nutrient.pdf
PY  - 2021
SP  - 29
T2  - American Journal of Clinical Nutrition
TI  - Small-quantity lipid-based nutrient supplements for children age 6-24 months: a systematic review and individual participant data meta-analysis of effects on developmental outcomes and effect modifiers
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34590116
UR  - https://watermark.silverchair.com/nqab277.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtowggLWBgkqhkiG9w0BBwagggLHMIICwwIBADCCArwGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMNq6ju-dkwKJEieNgAgEQgIICjceAAsfE74eHq5gsO1nUG9ohOMr_4d5rU2g7l_ZTrBuydhDt5KZtGoAAThUiq0IKqIqFZtRHpMVFVV2JXpPet7-mX5l_Xi0oSqpnDMRiyguEQvg1XidGE0PO6axhEpuk7E8VZEhD6hAJGXCR6HN4b4cst01vqtMKaaD4TuEGQ9l-2E_ZYjiQMON5dHXtdwsN4TICnNm_xtTU1DCJy_kBEggzZlkQeg1rof6qyqJ7iZ1xHFJ43I7G1twYseYlMzmk1iVK_8biskSDfcTlb7334teXjHq6ruib2x_Iq1LxTsXxfjvGG7xglCsjg76v_5XXqL_Bo2VHFqOJLlgqM7C83NZ_mQg0MDWovakbYvx4yOvkKQeNFFkL-J4iWlzCwJL5ILWH38sjbnx3Eu7b7Ed1l7hG8Ke_JCtvpsr8WMH0leCs6QKZBaJPdwLWrpmIF8hOIw4QFh8wRYqQIgkV3KV8FuxRwoDJQ9U74wpp5wev3h0nGWiXr1EJPLj0Uf2P91qJcfLIlB5QffcIHssz-TrEDPz8m64g5r9NfinxBIkgxZz4iZYqrWMOh2bzqv3ymEJqU8LVVpFrGR58p-7-EaKxgr_DuA5ztTWssXQoK8-c96wf2_B5W4cIc1TKEHT2HjY6D_kIyR1tw8hyoamzLwHlCA0oRf4uM1ZaZaj72TBxqjAQVFUgV4p3cfRff3OddUpWoq1Q1EZXFc2j7vEdjJNtdZxdQ9VEjzuXeTn1lmuGOWQXrE6q_T4zkCZZmeuP6wmnCtGD3Q0vdUH93p3fMuzYnVfR49YDJfEDVWSvOvMAFqqS_0fDGDlIe5IVReq9uDN5yMEuylSR_uUtjh7lDuX8omUQG7IHeekGdXvIODbr
VL  - 29
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Ultrasound examination of pregnancy before 24 weeks gestation may lead to more accurate dating and earlier diagnosis of pathology, but may also give false reassurance. It can be used to monitor development or diagnose conditions of an unborn baby. This review compares the effect of routine or universal, ultrasound examination, performed before 24 completed weeks&#039; gestation, with selective or no ultrasound examination.&nbsp; 

**OBJECTIVES**: To assess the effect of routine pregnancy ultrasound before 24 weeks as part of a screening programme, compared to selective ultrasound or no ultrasound, on the early diagnosis of abnormal pregnancy location, termination for fetal congenital abnormality, multiple pregnancy, maternal outcomes and later fetal compromise. To assess the effect of first trimester (before 14 weeks) and second trimester (14 to 24 weeks) ultrasound, separately. SEARCH METHODS: We searched Cochrane Pregnancy and Childbirth&#039;s Trials Register, ClinicalTrials.gov, and the World Health Organization&#039;s International Clinical Trials Registry Platform (ICTRP) on 11 August 2020. We also examined the reference lists of retrieved studies. SELECTION CRITERIA: We included randomised controlled trials (RCTs), quasi-RCTs, cluster-RCTs and RCTs published in abstract form. We included all trials with pregnant women who had routine or revealed ultrasound versus selective ultrasound, no ultrasound, or concealed ultrasound, before 24 weeks&#039; gestation. All eligible studies were screened for scientific integrity and trustworthiness. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed trials for eligibility and risk of bias, extracted data and checked extracted data for accuracy. Two review authors independently used the GRADE approach to assess the certainty of evidence for each outcome 

**MAIN RESULTS**: Our review included data from 13 RCTs including 85,265 women. The review included four comparisons. Four trials were assessed to be at low risk of bias for both sequence generation and allocation concealment and two as high risk. The nature of the intervention made it impossible to blind women and staff providing care to treatment allocation. &nbsp;Sample attrition was low in the majority of trials and outcome data were available for most women. Many trials were conducted before it was customary for trials to be registered and protocols published. First trimester routine versus selective ultrasound: four studies, 1791 women, from Australia, Canada, the United Kingdom (UK) and the United States (US). First trimester scans probably reduce short-term maternal anxiety about pregnancy (risk ratio (RR) 0.80, 95% confidence interval (CI) 0.65 to 0.99; moderate-certainty evidence). We do not have information on whether the&nbsp;reduction&nbsp;was sustained.&nbsp; The evidence is very uncertain about the effect of first trimester scans on perinatal loss (RR 0.97, 95% CI 0.55 to 1.73; 648 participants; one study; low-certainty evidence) or induction of labour for post-maturity (RR 0.83, 95% CI 0.50 to 1.37; 1474 participants; three studies; low-certainty evidence). The effect of routine first trimester ultrasound on birth before 34 weeks or termination of pregnancy for fetal abnormality was not reported. Second trimester routine versus selective ultrasound: seven studies, 36,053 women, from Finland, Norway, South Africa, Sweden and the US. Second trimester scans probably&nbsp;make little difference to perinatal loss (RR 0.98, 95% CI 0.81 to 1.20; 17,918 participants, three studies; moderate-certainty evidence) or intrauterine fetal death (RR 0.97, 95% CI 0.66 to 1.42; 29,584 participants, three studies; low-certainty evidence). Second trimester scans may reduce induction of labour for post-maturity (RR 0.48, 95% CI 0.31 to 0.73; 24,174 participants, six studies; low-certainty evidence), presumably by more accurate dating. Routine second trimester ultrasound may improve detection of multiple pregnancy (RR 0.05, 95% CI 0.02 to 0.16; 274 participants, five studies; low-certainty evidence). Routine second trimester ultrasound may increase detection of major fetal abnormality before 24 weeks (RR 3.45, 95% CI 1.67 to 7.12; 387 participants, two studies; low-certainty evidence) and probably increases the number of women terminating pregnancy for major anomaly (RR 2.36, 95% CI 1.13 to 4.93; 26,893 participants, four studies; moderate-certainty evidence). Long-term follow-up of children exposed to scans before birth did not indicate harm to children&#039;s physical or intellectual development (RR 0.77, 95% CI 0.44 to 1.34; 603 participants, one study; low-certainty evidence). The effect of routine second trimester ultrasound on birth before 34 weeks or maternal anxiety was not reported. Standard care plus two ultrasounds and referral for complications versus standard care: one cluster-RCT, 47,431 women, from Democratic Republic of Congo, Guatemala, Kenya,&nbsp;Pakistan and Zambia. This trial included a co-intervention, training of healthcare workers and referral for complications and was, therefore, assessed separately. Standard pregnancy care plus two scans, and training and referral for complications, versus standard care probably makes little difference to whether women with complications give birth in a risk appropriate setting with facilities for caesarean section (RR 1.03, 95% CI 0.89 to 1.19; 11,680 participants; moderate-certainty evidence). &nbsp;The intervention also probably makes little to no difference to low birthweight (&lt; 2500 g) (RR 1.01, 95% CI 0.90 to 1.13; 47,312 participants; moderate-certainty evidence). The evidence is very uncertain about whether the community intervention (including ultrasound) makes any difference to maternal mortality (RR 0.92, 95% CI 0.55 to 1.55; 46,768 participants; low-certainty evidence). Revealed ultrasound results (communicated to both patient and doctor) versus concealed ultrasound results (blinded to both patient and doctor at any time before 24 weeks): one study, 1095 women, from the UK. The evidence was very uncertain for all results relating to revealed versus concealed ultrasound scan (very low-certainty evidence). 

**AUTHORS&#039; CONCLUSIONS**: Early scans probably reduce short term maternal anxiety.&nbsp; Later scans may reduce labour induction for post-maturity. They may improve detection of major fetal abnormalities and increase the number of women who choose termination of pregnancy for this reason. They may also reduce the number of undetected twin pregnancies. All these findings accord with observational data.&nbsp; Neither type of scan appears to alter other important maternal or fetal outcomes, but our review may underestimate the effect in modern practice because trials were mostly &nbsp;from relatively early in the development of the technology, and many control participants also had scans. The trials were also underpowered to show an effect on other&nbsp;important maternal or fetal outcomes.
AD  - Department of Obstetrics and Gynaecology, Nottingham University Hospitals NHS Trust, Nottingham, UK.Nottingham China Health Institute, The University of Nottingham Ningbo, Ningbo, China.Division of Child Health, Obstetrics and Gynaecology, School of Medicine, University of Nottingham, Nottingham, UK.
AN  - 34438475
AU  - Kaelin
AU  - Agten,
AU  - A.
AU  - Xia,
AU  - J.
AU  - Servante,
AU  - J.
AU  - A.
AU  - Thornton,
AU  - J.
AU  - G.
AU  - Jones,
AU  - N.
AU  - W.
DA  - Aug 26
DB  - My EndNote Library.enl
DO  - 10.1002/14651858.Cd014698
DP  - NLM
J2  - The Cochrane database of systematic reviews
LA  - eng
N1  - 1469-493xKaelin Agten, AndreaXia, JunServante, Juliette AThornton, Jim GJones, Nia WJournal ArticleResearch Support, Non-U.S. Gov&#039;tReviewCochrane Database Syst Rev. 2021 Aug 26;8(8):CD014698. doi: 10.1002/14651858.CD014698.
PY  - 2021
SP  - Cd014698
T2  - Cochrane Database Syst Rev
TI  - Routine ultrasound for fetal assessment before 24 weeks&#039; gestation
VL  - 8
ER  -
TY  - JOUR
AB  - **Background**: Hegemonic masculinity has been recognized as contributing to the perpetration of different forms of gender-based violence (GBV). Abandoning hegemonic masculinities and promoting positive masculinities are both strategies used by interventions that foreground a &quot;gender-transformative approach.&quot; Preventing GBV among young people could be strengthened by engaging young men. In this article, we aim to systematically review the primary characteristics, methodological quality, and results of published evaluation studies of educational interventions that aim to prevent different forms of GBV through addressing hegemonic masculinities among young people. Main body: We conducted a systematic review of available literature (2008-2019) using Medline (PubMed), Scopus, Web of Science, PsycInfo, the CINAHL Complete Database, and ERIC as well as Google scholar. The Template for Intervention Description and Replication was used for data extraction, and the quality of the selected studies was analyzed using the Mixed Method Appraisal Tool. More than half of the studies were conducted in Africa (n = 10/15) and many were randomized controlled trials (n = 8/15). Most of the studies with quantitative and qualitative methodologies (n = 12/15) reported a decrease in physical GBV and/or sexual violence perpetration/victimization (n = 6/15). Longitudinal studies reported consistent results over time. 

**Conclusions**: Our results highlight the importance of using a gender-transformative approach in educational interventions to engage young people in critical thinking about hegemonic masculinity and to prevent GBV.
AN  - WOS:000675680200001
AU  - Perez-Martinez,
AU  - V.
AU  - Marcos-Marcos,
AU  - J.
AU  - Cerdan-Torregrosa,
AU  - A.
AU  - Briones-Vozmediano,
AU  - E.
AU  - Sanz-Barbero,
AU  - B.
AU  - Davo-Blanes,
AU  - M.
AU  - Daoud,
AU  - N.
AU  - Edwards,
AU  - C.
AU  - Salazar,
AU  - M.
AU  - La
AU  - Parra-Casado,
AU  - D.
AU  - Vives-Cases,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/15248380211030242
L1  - internal-pdf://0647284919/Perez-Martinez-Positive Masculinities and Gend.pdf
PY  - 2021
SP  - 19
T2  - Trauma Violence &amp; Abuse
TI  - Positive Masculinities and Gender-Based Violence Educational Interventions Among Young People: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000675680200001
UR  - https://journals.sagepub.com/doi/10.1177/15248380211030242
UR  - https://journals.sagepub.com/doi/pdf/10.1177/15248380211030242
ER  -
TY  - JOUR
AB  - Autism spectrum disorders (ASD) are an emerging health problem worldwide. So far, no definite cure for ASD exists. L-Carnosine is an amino acid containing beta-alanine and L-histidine which has been proposed to have neuroprotective, antioxidant and anti-convulsive properties that may benefit affected children with this disorder. 

This review aimed to assess the effect of L-Carnosine in the management of ASD in children. We systematically reviewed randomised controlled trials (RCTs) which documented the effect of L-Carnosine in children with ASD. A literature search was performed in PubMed, Cochrane Library, Google Scholar, ClinicalTrials.gov, Clinical Trial Registry-India databases from inception to December 20, 2020. Articles were selected based on pre-set inclusion/exclusion criteria. The primary outcomes were changes in social, communication and behavioural responses and the secondary outcomes were improvement in sleep disorders, gastrointestinal problems, oxidative stress markers and adverse effects. Jadad scale was used to assess the quality of RCTs and modified Cochrane risk of bias tool was used to check the risk of bias of the included studies. The meta-analysis was reported based on the fixed-effects model. Four double-blinded, placebo-controlled, RCTs and one open label trial with a total of 215 participants were selected for the review. All the trials were methodological of high quality according to the Jadad scale. The modified Cochrane risk of bias tool showed a low to high risk of bias. 

Results from the meta-analysis of three studies showed no significant difference between L-Carnosine and placebo groups in the Gilliam autism rating scale (GARS) (MD = - 2.57; 95% CI - 10.30, 5.16, p = 0.52) and in its socialisation (MD = - 1.51; 95% CI - 6.16, 3.14, p = 0.53), behaviour (MD = - 0.48; 95% CI - 4.82, 3.87, p = 0.83) and communication (MD = - 3.94; 95% CI - 10.00, 2.11, p = 0.20) subscales as well as the childhood autism rating scale (CARS) (MD = - 0.88; 95% CI - 6.96, 5.20; p = 0.78). 

Current data do not support the use of L-Carnosine in the management of children with ASD due to a low number of studies and sample size available. Further studies are warranted to know the effect of L-Carnosine for ASD management. Copyright &copy; 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, AT part of Springer Nature.
AD  - (Abraham, Rajanandh) Department of Pharmacy Practice, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu 600116, India (Undela) Department of Pharmacy Practice, National Institute of Pharmaceutical Education and Research, Guwahati, India (Narasimhan) Department of Paediatric Medicine, Sri Ramachandra Medical Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, IndiaM.G. Rajanandh, Department of Pharmacy Practice, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu 600116, India. E-mail: rajanandh.mg@sriramachandra.edu.in U. Narasimhan, Department of Paediatric Medicine, Sri Ramachandra Medical Centre, Sri Ramachandra Institute of Higher Education and Research, Chennai, India. E-mail: udayakumar.n@sriramachandra.edu.in
AN  - 2010770754
AU  - Abraham,
AU  - D.
AU  - A.
AU  - Undela,
AU  - K.
AU  - Narasimhan,
AU  - U.
AU  - Rajanandh,
AU  - M.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00726-021-02960-6
DP  - Ovid Technologies
KW  - Amino acids
KW  - Nutraceutical
KW  - Supplement
KW  - Vulnerable population
KW  - autism
KW  - child
KW  - Childhood Autism Rating Scale
KW  - clinical trial
KW  - clinical trial registry
KW  - Cochrane Library
KW  - controlled study
KW  - double blind procedure
KW  - drug therapy
KW  - female
KW  - gastrointestinal symptom
KW  - human
KW  - India
KW  - male
KW  - Medline
KW  - meta analysis
KW  - open study
KW  - outcome assessment
KW  - oxidative stress
KW  - randomized controlled trial (topic)
KW  - rating scale
KW  - review
KW  - risk assessment
KW  - sample size
KW  - sleep disorder
KW  - systematic review
KW  - amino acid
KW  - carnosine
KW  - placebo
L1  - internal-pdf://3715108525/Abraham-2021.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDate of Publication: 2021
PY  - 2021
T2  - Amino Acids.
TI  - Effect of L-Carnosine in children with autism spectrum disorders: a systematic review and meta-analysis of randomised controlled trials
UR  - http://link.springer.de/link/service/journals/00726/index.htm
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010770754
UR  - https://link.springer.com/article/10.1007/s00726-021-02960-6
UR  - https://link.springer.com/content/pdf/10.1007/s00726-021-02960-6.pdf
ER  -
TY  - JOUR
AB  - School-based programs seem promising for child abuse prevention. However, research mainly focused on sexual child abuse and knowledge is lacking on how individual program components contribute to the effectiveness of school-based prevention programs for any form of child abuse. 

This study aimed to examine the overall effect of these school-based programs on (a) children&#039;s child abuse-related knowledge and (b) self-protection skills by conducting two three-level meta-analyses. Furthermore, moderator analyses were performed to identify how program components and delivery techniques were associated with effectiveness. 

A literature search yielded 34 studies (158 effect sizes; N = 11,798) examining knowledge of child abuse and 22 studies (99 effect sizes; N = 7804) examining self-protection skills. A significant overall effect was found of school-based programs on both knowledge (d = 0.572, 95% CI [0.408, 0.737], p &lt; 0.001) and self-protection skills (d = 0.528, 95% CI [0.262, 0.794], p &lt; 0.001). The results of the first meta-analysis on children&#039;s child abuse knowledge suggest that program effects were larger in programs addressing social-emotional skills of children (d = 0.909 for programs with this component versus d = 0.489 for programs without this component) and self-blame (d = 0.776 versus d = 0.412), and when puppets (d = 1.096 versus d = 0.500) and games or quizzes (d = 0.966 versus d = 0.494) were used. The second meta-analysis on children&#039;s self-protections skills revealed that no individual components or techniques were associated with increased effectiveness. Several other study and program characteristics did moderate the overall effects and are discussed. 

In general, school-based prevention programs show positive effects on both knowledge and self-protection skills, and the results imply that program effectiveness can be improved by implementing specific components and techniques.
AN  - WOS:000658127600001
AU  - Gubbels,
AU  - J.
AU  - van
AU  - der
AU  - Put,
AU  - C.
AU  - E.
AU  - Stams,
AU  - Gjjm
AU  - Assink,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-021-00353-5
L1  - internal-pdf://0133275242/Gubbels-2021-Effective Components of School-Ba.pdf
PY  - 2021
SP  - 553-578
T2  - Clinical Child and Family Psychology Review
TI  - Effective Components of School-Based Prevention Programs for Child Abuse: A Meta-Analytic Review
UR  - &lt;Go to ISI&gt;://WOS:000658127600001
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8176877/pdf/10567_2021_Article_353.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - **Objectives** Involving parents and children in mindfulness-based interventions may holistically benefit family well-being. This meta-analysis systematically reviews and synthesizes the effects of mindfulness-based parallel-group (MBPG) interventions, which simultaneously involve parent and child, on family functioning, and the mental health of parents and children. 

**Methods** A total of 20 relevant studies were identified from 14 databases. The overall intervention effect size was estimated by pooled standardized mean difference. Moderator analyses were performed to explain the variability in intervention effects. Risk of bias and publication bias were also assessed. 

**Results** MBPG interventions showed minor-to-small positive effects on family functioning (d = 0.182, 95% CI [0.045, 0.319]), parental mental health (d = 0.238, 95% CI [0.110, 0.365]), and child mental health (d = 0.325, 95% CI [0.137, 0.513]). The effects of MBPG interventions on child mental health varied significantly by child age, child gender, recruitment setting, type of parent group, other activities in child group, other activities in parent group, and study design. 

**Conclusions** MBPG interventions show promising effects in improving mental health of both parents and children as well as in improving overall family functioning. However, significant variations exist in characteristics of participants, interventions, and study designs. Given the limited evidence currently available, more studies are needed to assess the determinants of effectiveness in MBPG interventions. Protocol Registration: PROSPERO #CRD42020164927
AN  - WOS:000687918200001
AU  - Xie,
AU  - Q.
AU  - W.
AU  - Dai,
AU  - X.
AU  - L.
AU  - Lyu,
AU  - R.
AU  - H.
AU  - Lu,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12671-021-01728-z
L1  - internal-pdf://0402871822/Xie-Effects of Mindfulness-Based Parallel-Grou.pdf
PY  - 2021
SP  - 22
T2  - Mindfulness
TI  - Effects of Mindfulness-Based Parallel-Group Interventions on Family Functioning and Child and Parent Mental Health: a Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000687918200001
UR  - https://link.springer.com/content/pdf/10.1007/s12671-021-01728-z.pdf
ER  -
TY  - JOUR
AB  - Top-tier evidence on the safety/tolerability of 80 medications in children/adolescents with mental disorders has recently been reviewed in this jour-nal. To guide clinical practice, such data must be combined with evidence on efficacy and acceptability. Besides medications, psychosocial inter-ventions and brain stimulation techniques are treatment options for children/adolescents with mental disorders. 

For this umbrella review, we systematically searched network meta-analyses (NMAs) and meta-analyses (MAs) of randomized controlled trials (RCTs) evaluating 48 medications, 20 psychosocial interventions, and four brain stimulation techniques in children/adolescents with 52 different mental disorders or groups of mental disorders, reporting on 20 different efficacy/acceptability outcomes. Co-primary outcomes were disease-specific symptom reduction and all-cause discontinuation (&quot;acceptability&quot;). We included 14 NMAs and 90 MAs, reporting on 15 mental disorders or groups of mental disorders. Overall, 21 medications outperformed placebo regarding the co-primary outcomes, and three psychosocial interventions did so (while seven outperformed waiting list/no treatment). Based on the meta-analytic evidence, the most convincing efficacy profile emerged for amphetamines, methylphenidate and, to a smaller extent, behavioral therapy in attention-deficit/hyperactivity disorder; aripiprazole, risperidone and several psychosocial interventions in autism; risperidone and behavioral interventions in disruptive behavior disorders; several antipsychotics in schizophrenia spectrum disorders; fluoxetine, the combination of fluoxetine and cognitive behavioral therapy (CBT), and interpersonal therapy in depression; aripiprazole in mania; fluoxetine and group CBT in anxiety disorders; fluoxetine/selective serotonin reuptake inhibitors, CBT, and behavioral therapy with exposure and response prevention in obsessive-compulsive disorder; CBT in post-traumatic stress disorder; imipramine and alarm behavioral intervention in enuresis; behavioral therapy in encopresis; and family therapy in anorexia nervosa. 

Results from this umbrella review of interventions for mental disorders in children/adolescents provide evidence-based information for clinical decision making.
AD  - Correll, Christoph U. Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York, NY, USA.Correll, Christoph U. Department of Psychiatry and Molecular Medicine, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.Correll, Christoph U. Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA.Correll, Christoph U. Department of Child and Adolescent Psychiatry, Charite Universitatsmedizin Berlin, Berlin, Germany.Cortese, Samuele. Center for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.Cortese, Samuele. Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK.Cortese, Samuele. Solent NHS Trust, Southampton, UK.Cortese, Samuele. Hassenfeld Children&#039;s Hospital at NYU Langone, New York University Child Study Center, New York, NY, USA.Cortese, Samuele. Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, UK.Croatto, Giovanni. Neurosciences Department, University of Padua, Padua, Italy.Monaco, Francesco. Department of Mental Health, ASL Salerno, Salerno, Italy.Krinitski, Damir. Integrated Psychiatry Winterthur, Winterthur, Switzerland.Arrondo, Gonzalo. Center for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.Arrondo, Gonzalo. Mind-Brain Group, Institute for Culture and Society, University of Navarra, Pamplona, Spain.Ostinelli, Edoardo G. Psychiatry Department, Oxford University, Oxford, UK.Zangani, Caroline. Department of Health Sciences, University of Milan, Milan, Italy.Fornaro, Michele. Department of Psychiatry, Federico II University, Naples, Italy.Estrade, Andres. Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Estrade, Andres. Department of Clinical and Health Psychology, Catholic University, Montevideo, Uruguay.Fusar-Poli, Paolo. Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Fusar-Poli, Paolo. OASIS Service, South London and Maudsley NHS Foundation Trust, London, UK.Fusar-Poli, Paolo. Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.Fusar-Poli, Paolo. Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Carvalho, Andre F. Department of Psychiatry, University of Toronto, Toronto, ON, Canada.Carvalho, Andre F. Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.Solmi, Marco. Neurosciences Department, University of Padua, Padua, Italy.Solmi, Marco. Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.
AN  - 34002501
AU  - Correll,
AU  - C.
AU  - U.
AU  - Cortese,
AU  - S.
AU  - Croatto,
AU  - G.
AU  - Monaco,
AU  - F.
AU  - Krinitski,
AU  - D.
AU  - Arrondo,
AU  - G.
AU  - Ostinelli,
AU  - E.
AU  - G.
AU  - Zangani,
AU  - C.
AU  - Fornaro,
AU  - M.
AU  - Estrade,
AU  - A.
AU  - Fusar-Poli,
AU  - P.
AU  - Carvalho,
AU  - A.
AU  - F.
AU  - Solmi,
AU  - M.
DA  - Jun
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/wps.20881
DP  - Ovid Technologies
J2  - World Psychiatry
L1  - internal-pdf://2004763615/Correll-2021.pdf
LA  - English
N1  - Correll, Christoph UCortese, SamueleCroatto, GiovanniMonaco, FrancescoKrinitski, DamirArrondo, GonzaloOstinelli, Edoardo GZangani, CarolineFornaro, MicheleEstrade, AndresFusar-Poli, PaoloCarvalho, Andre FSolmi, Marco
PY  - 2021
SP  - 244-275
T2  - World Psychiatry
TI  - Efficacy and acceptability of pharmacological, psychosocial, and brain stimulation interventions in children and adolescents with mental disorders: an umbrella review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34002501
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129843/pdf/WPS-20-244.pdf
VL  - 20
ER  -
TY  - JOUR
AB  - Small-quantity lipid-based nutrient supplements (SQ-LNSs) were designed to provide multiple micronutrients within a food base that also provides energy, protein, and essential fatty acids, targeted towards preventing malnutrition in vulnerable populations. 

Previous meta-analyses demonstrated beneficial effects of SQ-LNSs on child growth, anemia, and mortality. To further examine the efficacy and effectiveness of SQ-LNSs, and explore study-level and individual-level effect modifiers, we conducted an individual participant data meta-analysis of 14 randomized controlled trials of SQ-LNSs provided to children 6-24 mo of age (n &gt; 37,000). 

We examined growth, development, anemia, and micronutrient status outcomes. Children who received SQ-LNSs had a 12-14% lower prevalence of stunting, wasting, and underweight; were 16-19% less likely to score in the lowest decile for language, social-emotional, and motor development; had a 16% lower prevalence of anemia; and had a 64% lower prevalence of iron-deficiency anemia compared with control group children. 

For most outcomes, beneficial effects of SQ-LNSs were evident regardless of study-level characteristics, including region, stunting burden, malaria prevalence, sanitation, water quality, duration of supplementation, frequency of contact, or average reported compliance with SQ-LNSs. 

For development, the benefits of SQ-LNSs were greater in populations with higher stunting burden, in households with lower socioeconomic status, and among acutely malnourished children. For hemoglobin and iron status, benefits were greater in populations with higher anemia prevalence and among acutely malnourished children, respectively. Thus, targeting based on potential to benefit may be worthwhile for those outcomes. 

Overall, co-packaging SQ-LNSs with interventions that reduce constraints on response, such as the prevention and control of prenatal and child infections, improving health care access, and promotion of early child development, may lead to greater impact. 

Policymakers and program planners should consider including SQ-LNSs in strategies to reduce child mortality, stunting, wasting, anemia, iron deficiency, and delayed development. 

This study was registered at www.crd.york.ac.uk/PROSPERO as CRD42019146592, CRD42020159971, and CRD42020156663.
AN  - 34590696
AU  - Dewey,
AU  - K.
AU  - G.
AU  - Stewart,
AU  - C.
AU  - P.
AU  - Wessells,
AU  - K.
AU  - R.
AU  - Prado,
AU  - E.
AU  - L.
AU  - Arnold,
AU  - C.
AU  - D.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1093/ajcn/nqab279
L1  - internal-pdf://3542295061/Dewey-2021-Small-quantity lipid-based nutrient.pdf
PY  - 2021
SP  - 29
T2  - American Journal of Clinical Nutrition
TI  - Small-quantity lipid-based nutrient supplements for the prevention of child malnutrition and promotion of healthy development: overview of individual participant data meta-analysis and programmatic implications
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34590696
UR  - https://watermark.silverchair.com/nqab279.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtkwggLVBgkqhkiG9w0BBwagggLGMIICwgIBADCCArsGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMvrlD6j8AeY6YDUqVAgEQgIICjJEzPTmBpc_WnehyldQiKhhMXRItnjBc9wcD_mwdArG5JdEkPWKQX3BdLHZ-Xi2se0wHoPz9ez1Lc4YJgjs3DAUtj76vcrXeTN102WqjrOfYW-t6bgs-nsi0SWusP4kte7ywxfj6ZBcF-9MdR55knEy7he6wi5-BlJy13i-amU1BiamAUsj2iIYNhUUGH9jcMPg4oqvbAyD2dEIHeGJpuUyLLs6Zx1enpglIpf6YPZV4kqi6nqzHCm4T3WOm4fhKDSWGCICd8R4s6Ocazcyl9qozNWybUm2UZr39pMnusWduYGffFTJaiRe_tHwQ52Qkjq0R967i4MwiLgOrq3t5tAEq1LQXuIVRntGlxMtq9vl7D1DL5qb2525FYV-7caLWG3FnQH4vdfFCQY1qcW17qDkzb5ReOuQex9peGpysM9Ivdw_LwY2oRGMyPHECVilchjYB7OdZYtSE2KVPtJpsEzr2sYlvky662-bGbC-ZoeZkYA3spQYcNHW9rSFihM6AqLbNnBoPaWkO65vFpCE-O4GdfQl3hBv_H2MOhsWGZBy_ShO_KOzKN27R3SH0MDcWvU2Fa-vodh0IWFrZ9lDmNHjymohyI7LjRoKwH1ySZaj-glJ1Ns3VlDFMwmAQC3WY-94pdYSluatAk7pZeJtMnqnt9DJaFKPzAcCX8OnQFjj94w79hqly_8JeNuqBdI8npxhU4BbXyfWOnx7irpHQmeN2Ttyeq7pxbw7oRp8WfJ7l5byeyqJ3bdkM5Sdmc_uya2th_FXIwKaKLo-WHd0T8aTbuDLNGjVA3NVOsKWlcLLQvxKVOhq-XbGrRr6XMYh67-Y7m4_WFterLyPdZJJy7kHRX27RNYiIaX_GWUg
VL  - 29
ER  -
TY  - JOUR
AB  - Public Health Significance Statement This systematic review and meta-analysis sheds light on heterogeneity in the relationship between therapeutic alliance and intervention outcomes in youth internalizing disorders (anxiety, depression, and obsessive-compulsive disorder). 

We found preliminary evidence of heterogeneity with regards to problem type, timing of alliance measurement, and geographic location. This knowledge of &quot;for whom&quot; and &quot;under what circumstances&quot; the alliance contributes most strongly to outcomes can guide efforts to tailor and personalize interventions for youth internalizing disorders by leveraging the therapeutic alliance, thus, enhancing outcomes.

We report a systematic review and meta-analysis of studies examining the prospective relationship between therapeutic alliance and outcomes for youth ages 6 to 18 receiving intervention for internalizing disorders, with a primary aim to identify potential sources of heterogeneity. 

Twenty studies met criteria for the review and 18 studies met criteria for the meta-analysis. The overall size of the alliance-outcome relationship was small and positive (r = 0.18, p &lt; .01). The strength of the alliance-outcome relationship varied by problem type, alliance timing, and geographic location. Effect sizes were significantly smaller in studies of youth anxiety and significantly larger when alliance was measured between Sessions 4-6 and in studies conducted in the United States. 

We discuss study implications and methodological considerations for future studies.
AN  - WOS:000735540000001
AU  - Bose,
AU  - D.
AU  - Proenza,
AU  - D.
AU  - A.
AU  - Costales,
AU  - G.
AU  - Viswesvaran,
AU  - C.
AU  - Bickman,
AU  - L.
AU  - Pettit,
AU  - J.
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/cps0000052
L1  - internal-pdf://2609746332/Therapeutic Alliance in Psychosocial Intervent.pdf
PY  - 2021
SP  - 14
T2  - Clinical Psychology-Science and Practice
TI  - Therapeutic Alliance in Psychosocial Interventions for Youth Internalizing Disorders: A Systematic Review and Preliminary Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000735540000001
ER  -
TY  - JOUR
AB  - Considering the significant impact of perinatal depression on both maternal wellbeing and infant development, it is important to examine the effectiveness of interventions designed to prevent or reduce these risks. 

This systematic review and meta-analysis synthesised evidence on parenting intervention in relation to how such programs affect symptoms of perinatal depression and infant outcomes within 12 months of postpartum. 

We followed the Cochrane Collaboration guidelines on conducting systematic reviews and meta-analyses. A total of five electronic databases were searched for controlled trials that met pre-determined eligibility criteria. 

Outcomes of interest were maternal depressive symptoms and infants&#039; language, motor and socioemotional development. Seventeen studies involving 1665 participants were included in the systematic review. 

Estimates from a random effects model of 15 studies in the final meta-analysis revealed statistically significant reductions in maternal depressive symptoms at post-intervention for mothers allocated to receive parenting interventions (SMD = - 0.34, 95%CI - 0.44, - 0.24; z = 5.97, p &lt; 0.001; I&lt;sup&gt;2&lt;/sup&gt; = 0%). 

Data on infant development outcomes from the included studies were scarce, and therefore, infant outcomes were not analysed in this review. For individual study outcomes, the majority of studies reported a general trend for reductions in maternal depressive symptoms from pre- to post-intervention. 

Although parenting interventions are frequently considered preventive strategies that are designed to offer support to parents and impart skills that promote their physical and psychological wellbeing, our findings suggest that these interventions have a positive effect on perinatal depressive symptoms. Implications and recommendations for future research are addressed. 

The systematic review protocol was registered with PROSPERO 2020 CRD42020184491.
AN  - 34580804
AU  - Adina,
AU  - J.
AU  - Morawska,
AU  - A.
AU  - Mitchell,
AU  - A.
AU  - E.
AU  - McBryde,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s10567-021-00371-3
L1  - internal-pdf://1251611410/Adina-2021-Effect of Parenting Interventions o.pdf
PY  - 2021
SP  - 27
T2  - Clinical Child &amp; Family Psychology Review
TI  - Effect of Parenting Interventions on Perinatal Depression and Implications for Infant Developmental Outcomes: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34580804
UR  - https://link.springer.com/content/pdf/10.1007/s10567-021-00371-3.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - **Objectives**
Sports programs are widely implemented as measures of crime prevention. In contrast to their popularity, there is little systematic knowledge about their effectiveness. This systematic review and meta-analysis have been carried out to fill this gap. In a systematic review, we gathered data on evaluated prevention programs specifically designed to prevent crime and delinquency. We then conducted a meta-analytic integration with studies using at least roughly equivalent control groups for the program evaluation. 

**Method**
To retrieve relevant literature, we conducted a comprehensive international literature search until June 2021 drawing on scientific databases. We also applied snow-balling searches and contacted practitioners in the field. Studies were eligible if they evaluated sports programs designed to prevent delinquency on primary, secondary, and/or tertiary level. We focused on crime-related outcomes and potentially underlying psycho-social factors. We made no restrictions regarding characteristics of the participants or other aspects such as duration of the program. 

**Results**
24 studies were eligible for our systematic review, from which only thirteen were included into our meta-analytic integration. We found a moderate effect of participation in sports programs on crime-related outcomes (d = 0.36, p &lt; .001). Participants showed a significant decrease in outcomes such as aggressiveness or anti-social behavior. We also analyzed psychological outcomes such as self-esteem or mental well-being, which also significantly improved when participating in sports programs (d = 0.87, p &lt; ..05). 

**Conclusions* Sports programs seem to be an effective measure of crime prevention. However, future research needs more sound evaluation designs and moderator analyses to better understand the functioning and improve the implementation of sports programs.
AN  - WOS:000714999100001
AU  - Jugl,
AU  - I.
AU  - Bender,
AU  - D.
AU  - Losel,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10940-021-09536-3
L1  - internal-pdf://1890066575/Jugl-Do Sports Programs Prevent Crime and Redu.pdf
PY  - 2021
SP  - 52
T2  - Journal of Quantitative Criminology
TI  - Do Sports Programs Prevent Crime and Reduce Reoffending? A Systematic Review and Meta-Analysis on the Effectiveness of Sports Programs
UR  - &lt;Go to ISI&gt;://WOS:000714999100001
UR  - https://link.springer.com/content/pdf/10.1007/s10940-021-09536-3.pdf
ER  -
TY  - JOUR
AB  - **Background**: Recently, the literature suggested that placental transfusion facilitated by delayed cord clamping (DCC), besides having benefits on hematological parameters, might improve the infants&#039; brain development. Objective: The present review primarily evaluates the Ages and Stages Questionnaire (ASQ) total score mean difference (MD) at long-term follow-up (&gt;= 4 months) comparing DCC (&gt;90 or &gt;180 s) to early cord clamping (ECC). Secondary aims consisted of evaluating the ASQ domains&#039; MD and the results obtained from other methods adopted to evaluate the infants&#039; neurodevelopment. 

**Methods**: MEDLINE, Scopus, Cochrane, and databases were searched (up to 2nd November 2020) for systematic review and meta-analysis. All randomized controlled trials (RCTs) of term singleton gestations received DCC or ECC. Multiple pregnancies, pre-term delivery, non-randomized studies, and articles in languages other than English were excluded. The included studies were assessed for bias and quality. ASQ data were pooled stratified by time to follow up. 

**Results**: This meta-analysis of 4 articles from 3 RCTs includes 765 infants with four-month follow-up and 672 with 12 months follow-up. Primary aim (ASQ total score) pooled analysis was possible only for 12 months follow-up, and no differences were found between DCC and ECC (MD 1.1; CI 95: -5.1; 7.3). DCC approach significantly improves infants&#039; communication domains (MD 0.6; CI 95: 0.1; 1.1) and personal-social assessed (MD 1.0; CI 95: 0.3; 1.6) through ASQ at 12 months follow-up. Surprisingly, the four-month ASQ personal social domain (MD -1.6; CI 95: -2.8; -0.4) seems to be significantly lower in the DCC group than in the ECC group. 

**Conclusions**: DCC, a simple, non-interventional, and cost-effective approach, might improve the long-term infants&#039; neurological outcome. Single-blinding and limited studies number were the main limitations. Further research should be performed to confirm these observations, ideally with RCTs adopting standard methods to assess infants&#039; neurodevelopment.
AN  - WOS:000643553900001
AU  - Xodo,
AU  - S.
AU  - Xodo,
AU  - L.
AU  - Baccarini,
AU  - G.
AU  - Driul,
AU  - L.
AU  - Londero,
AU  - A.
AU  - P.
DA  - APR 12
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fped.2021.651410
L1  - internal-pdf://0685788172/Xodo-2021.pdf
PY  - 2021
T2  - FRONTIERS IN PEDIATRICS
TI  - Does Delayed Cord Clamping Improve Long-Term (&gt;= 4 Months) Neurodevelopment in Term Babies? A Systematic Review and a Meta-Analysis of Randomized Clinical Trials
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/651410/pubmed-zip/.versions/1/.package-entries/fped-09-651410/fped-09-651410.pdf?sv=2018-03-28&amp;sr=b&amp;sig=6EK%2B2DR1kPVsEBRWr%2Fqocj9aQj%2B8BWwAxwfvbF2y6fc%3D&amp;se=2021-06-24T14%3A35%3A27Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fped-09-651410.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - **Objective**
Assess the safety and efficacy of upcoming stem cell treatments and analyze their effects on the cognitive and behavioral impairments in patients diagnosed with autism. Methods We included controlled and noncontrolled, randomized and non-randomized trials evaluating stem cell therapy as a treatment in patients with autism spectrum disorder compared to placebo or without comparator. 

**Data Sources**
Scopus, Web of Science, MEDLINE and EMBASE. Risk of bias was assessed using Cochrane&#039;s Risk of Bias tool and the NIH&#039;s Quality Assessment Tool for Studies With No Control Group. 

**Results**
Eleven trials including 461 patients proved eligible. ABC scale meta-analysis showed a mean raw of -11.97 in the intervention groups (95 % CI -91.45 to 67.52, p &lt; 0.01). CARS scale reported a mean raw of -9.08 (95 % CI -15.43 to -2.73, p &lt; 0.01). VABS scale was reported by their domains: communication domain reported a mean raw of 2.69 (95 % CI 1.30 to 4.08, p = 0.92); daily living domain, 1.99 (95 % CI 0.83 to 3.15, p = 0.51); motor domain, 1.06 (95 % CI -0.37 to 2.48, p = 0.20); socialization domain, 3.09 (95 % CI 1.71 to 4.48, p = 0.61); adaptive behavior domain, 2.10 (95 % CI 1.04 to 3.16, p = 0.36). Furthermore, the most common side effects reported included fever, hyperactivity, vomit, headache, and aggressiveness; no serious adverse events were reported. 

**Conclusions**
The body of evidence suggests that stem cell therapy significantly improves scales in patients with autism spectrum disorder, hence, future studies should help us have more confidence in the results. We found no serious adverse events related to the stem cell therapy.
AN  - WOS:000695377700001
AU  - Villarreal-Martinez,
AU  - L.
AU  - Gonzalez-Martinez,
AU  - G.
AU  - Saenz-Flores,
AU  - M.
AU  - Bautista-Gomez,
AU  - A.
AU  - J.
AU  - Gonzalez-Martinez,
AU  - A.
AU  - Ortiz-Castillo,
AU  - M.
AU  - Robles-Saenz,
AU  - D.
AU  - A.
AU  - Garza-Lopez,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12015-021-10257-0
L1  - internal-pdf://0549569406/Villarreal-Mart-Stem Cell Therapy in the Treat.pdf
PY  - 2021
SP  - 10
T2  - Stem Cell Reviews and Reports
TI  - Stem Cell Therapy in the Treatment of Patients With Autism Spectrum Disorder: a Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000695377700001
UR  - https://link.springer.com/content/pdf/10.1007/s12015-021-10257-0.pdf
ER  -
TY  - JOUR
AB  - Past reviews of cyberbullying preventative interventions have critiqued the field regarding scientific rigor, and a meta-analysis found that randomized controlled trials (RCTs) of such interventions were more effective than non-RCTs. However, no review has examined the risk of bias, dosage, modality, and delivery context of such programs to date. The current study addresses this gap through a systematic review of the literature. Potential articles (N = 4,737) from 4 databases were identified and screened (Academic Search Premier including ERIC, PsychINFO, and the Psychology and Behavioral Collection; PubMed; Web of Science; Compendex); 72 articles were reviewed for eligibility. Final articles included (N = 30) were based on a rigorous search process guided by inclusion and exclusion criteria. The majority of studies were conducted in Europe; two were conducted in the USA, three in Australia, and two in the Middle East. Efforts to reduce risk of bias were evaluated using the Cochrane&#039;s Risk of Bias tool. Harvest plots were constructed to qualitatively illustrate the rigor, dosage, modality, and context of the interventions, and meta-analytic random effects models were conducted to examine effect sizes of the interventions on cyberbullying perpetration and victimization. Results suggest that cyberbullying interventions delivered through schools are effective, though expanded follow-up time is suggested, and additional evidence is needed for home settings and digital delivery.
AN  - 34714506
AU  - Doty,
AU  - J.
AU  - L.
AU  - Giron,
AU  - K.
AU  - Mehari,
AU  - K.
AU  - R.
AU  - Sharma,
AU  - D.
AU  - Smith,
AU  - S.
AU  - J.
AU  - Su,
AU  - Y.
AU  - W.
AU  - Ma,
AU  - X.
AU  - Rijo,
AU  - D.
AU  - Rousso,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s11121-021-01314-8
L1  - internal-pdf://3921204935/Doty-2021-The Dosage, Context, and Modality of.pdf
PY  - 2021
SP  - 29
T2  - Prevention Science
TI  - The Dosage, Context, and Modality of Interventions to Prevent Cyberbullying Perpetration and Victimization: a Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34714506
UR  - https://link.springer.com/content/pdf/10.1007/s11121-021-01314-8.pdf
VL  - 29
ER  -
TY  - JOUR
AB  - Physical exercise has a positive impact on anxiety and depression. However, the evidence that associates strength training with a decrease in adolescents&#039; psychosocial disorders is scarce. Consequently, the objective was to analyze the effects of training with different modes of strength intervention on anxiety, stress, and depression in adolescents. 

The search was designed according to PRISMA&lt;sup&gt; R&lt;/sup&gt;. We searched WoS, Scopus, SPORTDiscus, PubMed, and MEDLINE (2010-2020). Methodological quality and risk of bias were assessed with the Cochrane Collaboration. The analysis was carried out with a standardized mean difference (SMD) pooled using the Hedges g test (95% CI). The Main Outcome Measures were: anxiety, stress, and depression in adolescents post strength training. Nine studies were included in the systematic review and seven in the meta-analysis. 

These studies showed a large and significant effect of strength training on anxiety (SMD = -1.75; CI = 95%: -3.03, -0.48; p = 0.007) and depression (SMD = -1.61; CI = 95%: -2.54, -0.67, p = 0.0007). In conclusion, training with different modes of strength intervention have shown control over anxiety and depression in adolescents. However, conventional strength training seems to have better results than other modes of strength intervention.
AN  - 34574400
AU  - Barahona-Fuentes,
AU  - G.
AU  - Huerta
AU  - Ojeda,
AU  - A.
AU  - Chirosa-Rios,
AU  - L.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/ijerph18189477
L1  - internal-pdf://0849877230/Barahona-Fuente-2021-Effects of Training with.pdf
PY  - 2021
SP  - 08
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Effects of Training with Different Modes of Strength Intervention on Psychosocial Disorders in Adolescents: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34574400
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-14-00156/article_deploy/ijerph-14-00156.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Neurocognitive deficits are at the heart of explanatory models of ADHD and lead to significant impairments in daily life. Determine dosing effects of methylphenidate (MPH) on a broad range of neurocognitive functions and investigate possible impairing effects of high doses is therefore important. 

**METHOD: **
Placebo-controlled trials were included that investigated MPH dosing effects on neurocognitive functions in children (5-18 years) diagnosed with ADHD. Effect sizes (SMD) were calculated for different neurocognitive functions (baseline speed, variability in responding, non-executive memory and executive memory, inhibitory control and cognitive flexibility) and, if available, for ADHD symptoms. Meta-regression analysis were used to investigate linear effects of dose (mg/kg/dose) and separate meta-analyses compared SMDs for three MPH dose ranges: low (0.10-0.30 mg/kg/dose), medium (0.31-0.60 mg/kg/dose) and high dose (0.61-1.00 mg/kg/dose).

**RESULTS: **
Thirty-one studies fulfilled inclusion criteria comprising 804 children with ADHD. MPH had beneficial effects on all neurocognitive functions (d=0.20-0.73). Significant linear dosing effects were found for ADHD symptoms and lower-order neurocognitive functions (baseline speed, variability in responding, non-executive memory), with greater enhancement of functioning with increasing dose. No dosing effects were found for higher-order neurocognitive functions (executive memory, inhibitory control and cognitive flexibility). No detrimental effects for MPH were found on any of the investigated functions. 

**CONCLUSION: **
MPH is superior to placebo in improving ADHD symptoms and a broad range of neurocognitive functions, however effects sizes regarding the effects of dose vary substantially between functions. Our data highlights the importance of considering both neurocognitive and symptomatic aspects of ADHD in clinical practice.
AN  - 34534624
AU  - Vertessen,
AU  - K.
AU  - Luman,
AU  - M.
AU  - Staff,
AU  - A.
AU  - Bet,
AU  - P.
AU  - de
AU  - Vries,
AU  - R.
AU  - Twisk,
AU  - J.
AU  - Oosterlaan,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jaac.2021.08.023
L1  - internal-pdf://1750023518/Vertessen-2021-Meta-analysis_ Dose-dependent E.pdf
PY  - 2021
SP  - 11
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Meta-analysis: Dose-dependent Effects of Methylphenidate on Neurocognitive Functioning in Children With Attention-Deficit/Hyperactivity Disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34534624
UR  - https://www.jaacap.org/article/S0890-8567(21)01709-3/pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **BACKGROUND**: The prevention of mental disorders and promotion of mental health and well-being are growing fields. Whether mental health promotion and prevention interventions provide value for money in children, adolescents, adults, and older adults is unclear. The aim of the current study is to update 2 existing reviews of cost-effectiveness studies in this field in order to determine whether such interventions are cost-effective.

**METHODS AND FINDINGS**: Electronic databases (including MEDLINE, PsycINFO, CINAHL, and EconLit through EBSCO and Embase) were searched for published cost-effectiveness studies of prevention of mental disorders and promotion of mental health and well-being from 2008 to 2020. The quality of studies was assessed using the Quality of Health Economic Studies Instrument (QHES). The protocol was registered with PROSPERO (# CRD42019127778). The primary outcomes were incremental cost-effectiveness ratio (ICER) or return on investment (ROI) ratio across all studies. A total of 65 studies met the inclusion criteria of a full economic evaluation, of which, 23 targeted children and adolescents, 35 targeted adults, while the remaining targeted older adults. A large number of studies focused on prevention of depression and/or anxiety disorders, followed by promotion of mental health and well-being and other mental disorders. Although there was high heterogeneity in terms of the design among included economic evaluations, most studies consistently found that interventions for mental health prevention and promotion were cost-effective or cost saving. The review found that targeted prevention was likely to be cost-effective compared to universal prevention. Screening plus psychological interventions (e.g., cognitive behavioural therapy [CBT]) at school were the most cost-effective interventions for prevention of mental disorders in children and adolescents, while parenting interventions and workplace interventions had good evidence in mental health promotion. There is inconclusive evidence for preventive interventions for mental disorders or mental health promotion in older adults. While studies were of general high quality, there was limited evidence available from low- and middle-income countries. The review was limited to studies where mental health was the primary outcome and may have missed general health promoting strategies that could also prevent mental disorder or promote mental health. Some ROI studies might not be included given that these studies are commonly published in grey literature rather than in the academic literature.

**CONCLUSIONS**: Our review found a significant growth of economic evaluations in prevention of mental disorders or promotion of mental health and well-being over the last 10 years. Although several interventions for mental health prevention and promotion provide good value for money, the varied quality as well as methodologies used in economic evaluations limit the generalisability of conclusions about cost-effectiveness. However, the finding that the majority of studies especially in children, adolescents, and adults demonstrated good value for money is promising. Research on cost-effectiveness in low-middle income settings is required.TRIAL REGISTRATION: PROSPERO registration number: CRD42019127778.
AD  - Le, Long Khanh-Dao. Deakin University, Deakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Geelong, Australia.Esturas, Adrian Cuevas. Deakin University, Deakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Geelong, Australia.Mihalopoulos, Cathrine. Deakin University, Deakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Geelong, Australia.Chiotelis, Oxana. Deakin University, Deakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Geelong, Australia.Bucholc, Jessica. Deakin University, Deakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Geelong, Australia.Chatterton, Mary Lou. Deakin University, Deakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Geelong, Australia.Engel, Lidia. Deakin University, Deakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Geelong, Australia.
AN  - 33974641
AU  - Le,
AU  - L.
AU  - K.
AU  - Esturas,
AU  - A.
AU  - C.
AU  - Mihalopoulos,
AU  - C.
AU  - Chiotelis,
AU  - O.
AU  - Bucholc,
AU  - J.
AU  - Chatterton,
AU  - M.
AU  - L.
AU  - Engel,
AU  - L.
DA  - May
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pmed.1003606
DP  - Ovid Technologies
J2  - PLoS Med
L1  - internal-pdf://1195068835/Le-2021.pdf
LA  - English
N1  - Le, Long Khanh-DaoEsturas, Adrian CuevasMihalopoulos, CathrineChiotelis, OxanaBucholc, JessicaChatterton, Mary LouEngel, Lidia
PY  - 2021
SP  - e1003606
T2  - PLoS Medicine / Public Library of Science
TI  - Cost-effectiveness evidence of mental health prevention and promotion interventions: A systematic review of economic evaluations
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33974641
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8148329/pdf/pmed.1003606.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - This study analyzed the effects of various alcohol prevention programs on the drinking behavior of adolescents. There were seven electronic databases used for the literature search. A systematic review and meta-analysis are employed for works published in Korean and English from January 2010 to April 2021, with strict inclusion criteria yielding 12 papers in the review. The type of alcohol prevention interventions included educational and motivational interventions. Six studies had more than 500 participants each, and five studies had more than 10 participating schools. The programs did not effectively reduce the frequency of drinking or binge drinking of adolescents but significantly reduced the amount of alcohol consumed. Based on the results of this study, when planning alcohol prevention programs for adolescents, it is necessary to adopt a multi-level ap-proach, including the engagement of parents and the community. Copyright &copy; 2021 by the authors. Licensee MDPI, Basel, Switzerland.
AN  - 2013371927
AU  - Cho,
AU  - M.
AU  - K.
AU  - Cho,
AU  - Y.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph18168524
L1  - internal-pdf://0588327906/Cho-2021-Do alcohol prevention programs influe.pdf
PY  - 2021
T2  - International Journal of Environmental Research and Public Health
TI  - Do alcohol prevention programs influence adolescents&#039; drinking behaviors? A systematic review and meta-analysis
UR  - https://www.mdpi.com/1660-4601/18/16/8524/pdf
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-18-08524/article_deploy/ijerph-18-08524-v2.pdf
VL  - 18 (16) (no pagination)
ER  -
TY  - JOUR
AB  - **Abstract**
**Background**
Multisystemic Therapy&reg; (MST&reg;) is an intensive, home-based intervention for families of youth with social, emotional, and behavioural problems. MST therapists engage family members in identifying and changing individual, family, and environmental factors thought to contribute to problem behaviour. Intervention may include efforts to improve communication, parenting skills, peer relations, school performance, and social networks. MST is widely considered to be a well-established, evidence-based programme. 

**Objectives**
We assessed (1) impacts of MST on out-of-home placements, crime and delinquency, and other behavioural and psychosocial outcomes for youth and families; (2) consistency of effects across studies; and (3) potential moderators of effects including study location, evaluator independence, and risks of bias. 

**Search Methods**
Searches were performed in 2003, 2010, and March to April 2020. We searched PsycINFO, MEDLINE, ERIC, NCJRS Abstracts, ProQuest and WorldCAT dissertations and theses, and 10 other databases, along with government and professional websites. Reference lists of included articles and research reviews were examined. Between April and August 2020 we contacted 22 experts in search of missing data on 16 MST trials. 

**Selection Criteria**
Eligible studies included youth (ages 10 to 17) with social, emotional, and/or behavioural problems who were randomly assigned to licensed MST programmes or other conditions. There were no restrictions on publication status, language, or geographic location. 

**Data Collection and Analysis**
Two reviewers independently screened 1802 titles and abstracts, read all available study reports, assessed study eligibility, and extracted data onto structured electronic forms. We assessed risks of bias (ROB) using modified versions of the Cochrane ROB tool and What Works Clearinghouse standards. Where possible, we used random effects models with inverse variance weights to pool results across studies. We used odds ratios for dichotomous outcomes and standardised mean differences for continuous outcomes. We used Hedges g to adjust for small sample sizes. We assessed the heterogeneity of effects with &chi;2 and I 2. Pairwise meta-analyses are displayed in forest plots, with studies arranged in subgroups by location (USA or other country) and investigator independence. We provide separate forest plots for conceptually distinct outcomes and endpoints. We assessed differences between subgroups of studies with &chi; 2 tests. We generated robust variance estimates, using correlated effects (CE) models with small sample corrections to synthesise all available outcome measures within each of nine outcome domains. Exploratory CE analyses assessed potential moderators of effects within these domains. We used GRADE guidelines to assess the certainty of evidence on seven primary outcomes at one year after referral. 

**Main Results**
Twenty-three studies met our eligibility criteria; these studies included a total of 3987 participating families. Between 1983 and 2020, 13 trials were conducted in the USA by MST program developers and 10 studies were conducted by independent teams (three in the USA, three in the UK, and one each in Canada, the Netherlands, Norway, and Sweden). These studies examined outcomes of MST for juvenile offenders, sex offenders, offenders with substance abuse problems, youth with conduct or behaviour problems, those with serious mental health problems, autism spectrum disorder, and cases of child maltreatment. We synthesised data from all eligible trials to test the claim that MST is effective across clinical problems and populations. Most trials compared MST to treatment as usual (TAU). In the USA, TAU consisted of relatively little contact and few services for youth and families, compared with more robust public health and social services available to youth in other high-income countries. One USA study provided &ldquo;enhanced TAU&rdquo; to families in the control group, and two USA studies compared MST to individual therapy for youth. The quality of available evidence for M T is mixed. We identified high risks of bias due to: inadequate randomisation procedures (in 9% of studies); lack of comparability between groups at baseline (65%); systematic omission of cases (43%); attrition (39%); confounding factors (e.g., between-group differences in race, gender, and attention; 43%); selective reporting of outcomes (52%); and conflicts of interest (61%). Most trials (96%) have high risks of bias on at least one indicator. GRADE ratings of the quality of evidence are low or moderate for seven primary outcomes, with high-quality evidence from non-USA studies on out-of-home placement. Effects of MST are not consistent across studies, outcomes, or endpoints. At one year post randomisation, available evidence shows that MST reduced out-of-home placements in the USA (OR 0.52, 95% confidence interval [CI] 0.32 to 0.84; P&thinsp;&lt;&thinsp;.01), but not in other countries (OR 1.14, CI 0.84 to 1.55; P&thinsp;=&thinsp;.40). There is no overall evidence of effects on other primary outcomes at one year. When we included all available outcomes in CE models, we found that MST reduced placements and arrests in the USA, but not in other countries. At 2.5 years, MST increased arrest rates in non-USA countries (OR 1.27, CI 1.01 to 1.60; P =&thinsp;.04) and increased substance use by youth in the UK and Sweden (SMD 0.13, CI &minus;0.00 to 0.27; P&thinsp;=&thinsp;.05). CE models show that MST reducesd self-reported delinquency and improved parent and family outcomes, but there is no overall evidence of effects on youth symptoms, substance abuse, peer relations, or school outcomes. Prediction intervals indicate that future studies are likely to find positive or negative effects of MST on all outcomes. Potential moderators are confounded: USA studies led by MST developers had higher risks of bias, and USA control groups received fewer services and had worse outcomes than those in independent trials conducted in other high-income countries. The USA/non-USA contrast appears to be more closely related to effect sizes than than investigator independence or risks of bias. 

**Authors&#039; Conclusions**
The quality of evidence for MST is mixed and effects are inconsistent across studies. Reductions in out-of-home placements and arrest/conviction were observed in the USA, but not in other high-income countries. Studies that compared MST to more active treatments showed fewer benefits, and there is evidence that MST may have had some negative effects on youth outside of the USA. Based on moderate to low quality evidence, MST may reduce self-reported delinquency and improve parent and family outcomes, but there is no overall evidence of effects on youth symptoms, substance abuse, peer relations, or school outcomes.
AU  - Littell,
AU  - Julia
AU  - H.
AU  - Pigott,
AU  - Therese
AU  - D.
AU  - Nilsen,
AU  - Karianne
AU  - H.
AU  - Green,
AU  - Stacy
AU  - J.
AU  - Montgomery,
AU  - Olga
AU  - L.
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/cl2.1158
PY  - 2021
SP  - e1158
T2  - Campbell Systematic Reviews
TI  - Multisystemic Therapy&reg; for social, emotional, and behavioural problems in youth age 10 to 17: An updated systematic review and meta-analysis
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/cl2.1158
VL  - 17
ER  -
TY  - JOUR
AB  - **Question**
Suicide is a global public and mental health problem. The effectiveness of social support interventions has not been widely demonstrated in the prevention of suicide. We aimed to describe the methods of social support interventions in preventing suicide and examine the efficacy of them. 

**Study selection and analysis**
We searched literature databases and conducted clinical trials. The inclusion criteria for the summary of intervention methods were as follows: (1) studies aimed at preventing suicide through method(s) that directly provide social support; (2) use of one or more method(s) to directly provide social support. The additional inclusion criteria for meta-analysis on the efficacy of these interventions included: (1) suicide, suicide attempt or social support-related outcome was measured; (2) randomised controlled trial design and (3) using social support intervention as the main/only method. 

**Findings**
In total, 22 656 records and 185 clinical trials were identified. We reviewed 77 studies in terms of intervention methods, settings, support providers and support recipients. There was a total of 18 799 person-years among the ten studies measuring suicide. The number of suicides was significantly reduced in the intervention group (risk ratio (RR)=0.48, 95% CI 0.27 to 0.85). In 14 studies with a total of 14 469 person-years, there was no significant reduction of suicide attempts in the overall pooled RR of 0.88 (95% CI 0.73 to 1.07). 

**Conclusions**
Social support interventions were recommended as a suicide prevention strategy for those with elevated suicide risk.
AN  - WOS:000731097900001
AU  - Hou,
AU  - X.
AU  - F.
AU  - Wang,
AU  - J.
AU  - L.
AU  - Guo,
AU  - J.
AU  - Zhang,
AU  - X.
AU  - X.
AU  - Liu,
AU  - J.
AU  - H.
AU  - Qi,
AU  - L.
AU  - M.
AU  - Zhou,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/ebmental-2021-300318
L1  - internal-pdf://2177441310/Hou-Methods and efficacy of social support int.pdf
PY  - 2021
SP  - 7
T2  - Evidence-Based Mental Health
TI  - Methods and efficacy of social support interventions in preventing suicide: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000731097900001
UR  - https://ebmh.bmj.com/content/ebmental/early/2021/12/14/ebmental-2021-300318.full.pdf
ER  -
TY  - JOUR
AB  - Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder affecting multiple developmental domains including social communication, behavioral-affective, sensorimotor, and cognitive systems. There is growing evidence for the use of holistic, whole-body, Creative Movement Therapies (CMT) such as music, dance, yoga, theater, and martial arts in addressing the multisystem impairments in ASD. 

We conducted a comprehensive quantitative and qualitative review of the evidence to date on the effects of CMT on multiple systems in individuals with ASD. The strongest evidence, both in terms of quantity and quality, exists for music and martial arts-based interventions followed by yoga and theater, with very limited research on dance-based approaches. Our review of 72 studies (N = 1,939 participants) across participants with ASD ranging from 3 to 65 years of age suggests that at present there is consistent evidence from high quality studies for small-to-large sized improvements in social communication skills following music and martial arts therapies and medium-to-large improvements in motor and cognitive skills following yoga and martial arts training, with insufficient evidence to date for gains in affective, sensory, and functional participation domains following CMT. 

Although promising, our review serves as a call for more rigorous high-quality research to assess the multisystem effects of CMT in ASD. Based on the existing literature, we discuss implications of our findings for autism researchers and also provide evidence-based guidelines for clinicians to incorporate CMT approaches in their plan of care for individuals with ASD. Copyright &copy; 2021 Amonkar, Su, Bhat and Srinivasan.
AN  - 636565736
AU  - Amonkar,
AU  - N.
AU  - Su,
AU  - W.
AU  - C.
AU  - Bhat,
AU  - A.
AU  - N.
AU  - Srinivasan,
AU  - S.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2021.722874
L1  - internal-pdf://1158941302/fpsyt-12-722874.cleaned.pdf
PY  - 2021
T2  - Frontiers in Psychiatry
TI  - Effects of Creative Movement Therapies on Social Communication, Behavioral-Affective, Sensorimotor, Cognitive, and Functional Participation Skills of Individuals With Autism Spectrum Disorder: A Systematic Review
UR  - http://www.frontiersin.org/Psychiatry
VL  - 12 (no pagination)
ER  -
TY  - JOUR
AB  - **LAY ABSTRACT**
Interventions to address core symptoms for young children on the autism spectrum have a strong and growing evidence base. Adapting and delivering evidence-based interventions to infants and toddlers with a high likelihood for autism is a logical next step. This systematic review and meta-analysis summarize the association between infant and toddler interventions and developmental and family outcomes. Results indicate that these early interventions are effective for improving parent implementation of core strategies, yet the effects do not readily translate to child outcomes. However, key studies demonstrate conditional results that indicate that parent implementation is associated with child outcome. Implications for research and practice toward building adaptive interventions that respond to parent implementation and changing child characteristics are discussed.
AN  - 34628968
AU  - Hampton,
AU  - L.
AU  - H.
AU  - Rodriguez,
AU  - E.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/13623613211050433
L1  - internal-pdf://0869583366/Hampton-2021-Preemptive interventions for infa.pdf
PY  - 2021
SP  - 13623613211050433
T2  - Autism
TI  - Preemptive interventions for infants and toddlers with a high likelihood for autism: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34628968
UR  - https://journals.sagepub.com/doi/pdf/10.1177/13623613211050433
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis aimed to summarize the effects of forest therapy on depression and anxiety using data obtained from randomized controlled trials (RCTs) and quasiexperimental studies. We searched SCOPUS, PubMed, MEDLINE(EBSCO), Web of science, Embase, Korean Studies Information Service System, Research Information Sharing Service, and DBpia to identify relevant studies published from January 1990 to December 2020 and identified 20 relevant studies for the synthesis. The methodological quality of eligible primary studies was assessed by ROB 2.0 and ROBINS-I. Most primary studies were conducted in the Republic of Korea except for one study in Poland. Overall, forest therapy significantly improved depression (Hedges&#039;s g = 1.133; 95% confidence interval (CI): -1.491 to -0.775) and anxiety (Hedges&#039;s g = 1.715; 95% CI: -2.519 to -0.912). The quality assessment resulted in five RCTs that raised potential concerns in three and high risk in two. Fifteen quasi-experimental studies raised high for nine quasi-experimental studies and moderate for six studies. In conclusion, forest therapy is preventive management and nonpharmacologic treatment to improve depression and anxiety. However, the included studies lacked methodological rigor and required more comprehensive geographic application. Future research needs to determine optimal forest characteristics and systematic activities that can maximize the improvement of depression and anxiety. Copyright &copy; 2021 by the authors. Licensee MDPI, Basel, Switzerland.
AN  - 2014735648
AU  - Yeon,
AU  - P.
AU  - S.
AU  - Jeon,
AU  - J.
AU  - Y.
AU  - Jung,
AU  - M.
AU  - S.
AU  - Min,
AU  - G.
AU  - M.
AU  - Kim,
AU  - G.
AU  - Y.
AU  - Han,
AU  - K.
AU  - M.
AU  - Shin,
AU  - M.
AU  - J.
AU  - Jo,
AU  - S.
AU  - H.
AU  - Kim,
AU  - J.
AU  - G.
AU  - Shin,
AU  - W.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph182312685
L1  - internal-pdf://0099249457/Effect of forest therapy on depression an-2021.pdf
PY  - 2021
T2  - International Journal of Environmental Research and Public Health
TI  - Effect of forest therapy on depression and anxiety: A systematic review and meta-analysis
UR  - https://www.mdpi.com/1660-4601/18/23/12685/pdf
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-18-12685/article_deploy/ijerph-18-12685-v2.pdf?version=1638417418
VL  - 18(23) (no pagination)
ER  -
TY  - JOUR
AB  - Rates of self-harm amongst children appear to be increasing. This presents challenges for practitioners responsible for maintaining the safety of children admitted to mental health inpatient settings. Policy guidelines recommend that practitioners should aim to avoid the use of restrictive practices for children. It is currently unclear, however, what evidence-based alternatives to restrictive practices are available. We aimed to identify what non-restrictive interventions have been proposed to reduce self-harm amongst children in mental health inpatient settings and to evaluate the evidence supporting their use in clinical practice. A systematic search of five databases (CINAHL, Embase, Ovid MEDLINE, APA Psycinfo, and Cochrane) was conducted to identify articles reporting on non-restrictive interventions aimed at reducing self-harm amongst children in mental health inpatient settings. Articles were quality assessed and relevant data were extracted and synthesized using narrative synthesis. Searches identified relatively few relevant articles (n = 7) and these were generally of low methodological quality. The underlying theoretical assumptions and putative mechanisms of change for the interventions described were often unclear. Despite concerns about the rates of self-harm amongst children in mental health inpatient settings, there is a lack of high-quality research to inform clinical practice. There is an urgent need to develop effective non-restrictive interventions aimed at reducing self-harm for children using inpatient mental health services. Intervention development should be theoretically informed and be conducted in collaboration with people who have lived experience of this issue. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-93594-001
AU  - Griffiths,
AU  - R.
AU  - Dawber,
AU  - A.
AU  - McDougall,
AU  - T.
AU  - Midgley,
AU  - S.
AU  - Baker,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/inm.12940
L1  - internal-pdf://0081442992/Griffiths-2021-Non-restrictive interventions t.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - International Journal of Mental Health Nursing
TI  - Non-restrictive interventions to reduce self-harm amongst children in mental health inpatient settings: Systematic review and narrative synthesis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-93594-001
UR  - https://onlinelibrary.wiley.com/doi/10.1111/inm.12940
ER  -
TY  - JOUR
AB  - This report provides a review of randomized controlled trials that tested whether an eating disorder prevention program significantly reduced future onset of eating disorders, which is important because eating disorders are common and result in marked functional impairment. 

We identified 15 trials involving 5080 participants (mean ages ranging from 14.5 to 22.3) that reported 19 tests of whether selective eating disorder prevention programs significantly reduced future onset of eating disorders relative to some type of minimal control condition or a credible alternative intervention. Healthy lifestyle modification prevention programs, dissonance-based prevention programs, and a self-esteem/self-efficacy prevention program significantly reduced future onset of eating disorders, though the later was only evaluated in one trial. 

Psychoeducational, cognitive behavioral, behavioral weight gain, interpersonal, and family-therapy-based prevention programs did not significantly reduce future onset of eating disorders. The average prevention effect size was statistically significant (OR = 1.64, 95% CI = [1.09, 2.46], t = 2.54, p = .020) and there was heterogeneity in effect sizes (Q [18] = 35.96, p = .007). Prevention effects were significantly larger for trials that recruited participants with elevations on a single risk factor versus with elevations in multiple risk factors and for healthy lifestyle modification prevention programs versus cognitive behavioral prevention programs, though the remaining examined factors did not moderate intervention effect sizes (e.g., risk of bias). 

The fact that lifestyle modification and dissonance-based prevention programs significantly reduced future onset of eating disorders in multiple trials, producing a 54% to 77% reduction in future eating disorder onset implies that broadly implementing these prevention programs could reduce the population prevalence of eating disorders.
AN  - WOS:000661242100005
AU  - Stice,
AU  - E.
AU  - Onipede,
AU  - Z.
AU  - A.
AU  - Marti,
AU  - C.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.cpr.2021.102046
L1  - internal-pdf://3071141082/Stice-2021-A meta-analytic review of trials th.pdf
PY  - 2021
SP  - 17
T2  - Clinical Psychology Review
TI  - A meta-analytic review of trials that tested whether eating disorder prevention programs prevent eating disorder onset
UR  - &lt;Go to ISI&gt;://WOS:000661242100005
VL  - 87
ER  -
TY  - JOUR
AB  - **Objective:** 
The current systematic review aimed to provide comprehensive data on the effects of iodine supplementation in pregnancy and investigate its potential benefits on infant growth parameters and neurocognitive development using meta-analysis.

**Methods:** 
A systematic review was conducted on trials published from January 1989 to December 2019 by searching MEDLINE, Web of Science, the Cochrane Library, Scopus, and Google Scholar. For most maternal and neonatal outcomes, a narrative synthesis of the data was performed. For birth anthropometric measurements and infant neurocognitive outcomes, the pooled standardized mean differences (SMDs) with 95% CIs were estimated using fixed/random effect models.

**Results:** 
Fourteen trials were eligible for inclusion in the systematic review, of which five trials were included in the meta-analysis. Although the findings of different thyroid parameters are inconclusive, more consistent evidence showed that iodine supplementation could prevent the increase in thyroglobulin concentration during pregnancy. In the meta-analysis, no differences were found in weight (-0.11 (95% CI: -0.23 to 0.01)), length (-0.06 (95% CI: -0.21 to 0.09)), and head circumference (0.26 (95% CI: -0.35 to 0.88)) at birth, or in cognitive (0.07 (95% CI: -0.07 to 0.20)), language (0.06 (95% CI: -0.22 to 0.35)), and motor (0.07 (95% CI: -0.06 to 0.21)) development during the first 2 years of life in infants between the iodine-supplemented and control groups.

**Conclusion:** 
Iodine supplementation during pregnancy can improve the iodine status in pregnant women and their offspring; however, according to our meta-analysis, there was no evidence of improved growth or neurodevelopmental outcomes in infants of iodine-supplemented mothers.
AD  - Nazeri, Pantea. Family Health Institute, Breastfeeding Research Center, Tehran University of Medical Sciences, Tehran, Iran.Shariat, Mamak. Family Health Institute, Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran.Azizi, Fereidoun. Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
AN  - 33112293
AU  - Nazeri,
AU  - P.
AU  - Shariat,
AU  - M.
AU  - Azizi,
AU  - F.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1530/EJE-20-0927
DP  - Ovid Technologies
J2  - Eur
KW  - *Child Development/de [Drug Effects]
KW  - Clinical Trials as Topic
KW  - Congenital Hypothyroidism/pc [Prevention &amp; Control]
KW  - *Dietary Supplements
KW  - Female
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - *Iodine/ad [Administration &amp; Dosage]
KW  - Iodine/bl [Blood]
KW  - Male
KW  - *Maternal Nutritional Physiological Phenomena
KW  - Pregnancy
KW  - Pregnancy Complications/pc [Prevention &amp; Control]
KW  - Pregnancy Trimesters/bl [Blood]
KW  - *Prenatal Care/mt [Methods]
KW  - 9679TC07X4 (Iodine)
L1  - internal-pdf://4032299340/Nazeri-2021.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Nazeri, PanteaShariat, MamakAzizi, FereidounEJE-20-0927
PY  - 2021
SP  - 91-106
T2  - European Journal of Endocrinology
TI  - Effects of iodine supplementation during pregnancy on pregnant women and their offspring: a systematic review and meta-analysis of trials over the past 3 decades
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=33112293
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33112293&amp;id=doi:10.1530%2FEJE-20-0927&amp;issn=0804-4643&amp;isbn=&amp;volume=184&amp;issue=1&amp;spage=91&amp;pages=91-106&amp;date=2021&amp;title=European+Journal+of+Endocrinology&amp;atitle=Effects+of+iodine+supplementation+during+pregnancy+on+pregnant+women+and+their+offspring%3A+a+systematic+review+and+meta-analysis+of+trials+over+the+past+3+decades.&amp;aulast=Nazeri&amp;pid=%3Cauthor%3ENazeri+P%3C%2Fauthor%3E%3CAN%3E33112293%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://eje.bioscientifica.com/view/journals/eje/184/1/EJE-20-0927.xml
UR  - https://eje.bioscientifica.com/downloadpdf/journals/eje/184/1/EJE-20-0927.pdf
VL  - 184
ER  -
TY  - JOUR
AB  - **CONTEXT**: In several studies, authors have reported on cognitive behavioral therapy (CBT) for children and adolescents with autism spectrum disorders (ASDs), but inconsistent treatment effectiveness was revealed from these studies.

**OBJECTIVE**: To evaluate the effectiveness of CBT on the symptoms of ASD and social-emotional problems in children or adolescents with ASD by using a meta-analytic approach.

**DATA SOURCES**: Data sources included PubMed, Embase, and the Cochrane Library.

**STUDY SELECTION**: We selected randomized controlled trials (RCTs) in which authors reported effectiveness of CBT on the symptoms of ASD and social-emotional problems in children or adolescents with ASD from database inception to May 2019.

**DATA EXTRACTION**: For each study, 2 authors extracted data on the first author&#039;s surname, publication year, country, sample size, mean age, CBT target, intervention, outcome measurement, follow-up duration, and investigated outcomes.

**RESULTS**: Forty-five RCTs and 6 quasi RCTs of 2485 children and adolescents with ASDs were selected for the final meta-analysis. There was no significant difference between CBT and control for symptoms related to ASD based on self-reported outcomes (standard mean difference: -0.09; 95% confidence interval: -0.42 to 0.24; P = .593), whereas CBT significantly improved the symptoms related to ASD based on informant-reported outcomes, clinician-rated outcomes, and task-based outcomes. Moreover, the pooled standard mean differences indicated that CBT has no significant effect on symptoms of social-emotional problems based on self-reported outcomes.

**LIMITATIONS**: The quality of included studies was low to modest, significant heterogeneity among the included studies for all investigated outcomes was detected, and publication bias was inevitable.

**CONCLUSIONS**: These findings indicate that CBT may significantly improve the symptoms of ASD and social-emotional problems in children or adolescents with ASD.
AD  - Wang, Xinyuan. Contributed equally as co-first authors.Zhao, Jinzhu. Contributed equally as co-first authors.
AN  - 33888566
AU  - Wang,
AU  - X.
AU  - Zhao,
AU  - J.
AU  - Huang,
AU  - S.
AU  - Chen,
AU  - S.
AU  - Zhou,
AU  - T.
AU  - Li,
AU  - Q.
AU  - Luo,
AU  - X.
AU  - Hao,
AU  - Y.
DA  - Apr 22
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1542/peds.2020-049880
DP  - Ovid Technologies
J2  - Pediatrics
L1  - internal-pdf://1869419798/Wang-2021.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingAprWang, XinyuanZhao, JinzhuHuang, ShanChen, ShulingZhou, TuoLi, QingLuo, XiaopingHao, Yane2020049880
PY  - 2021
SP  - 22
T2  - Pediatrics
TI  - Cognitive Behavioral Therapy for Autism Spectrum Disorders: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33888566
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33888566&amp;id=doi:10.1542%2Fpeds.2020-049880&amp;issn=0031-4005&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Pediatrics&amp;atitle=Cognitive+Behavioral+Therapy+for+Autism+Spectrum+Disorders%3A+A+Systematic+Review.&amp;aulast=Wang&amp;pid=%3Cauthor%3EWang+X%3C%2Fauthor%3E%3CAN%3E33888566%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pediatrics.aappublications.org/content/147/5/e2020049880
UR  - https://pediatrics.aappublications.org/content/pediatrics/147/5/e2020049880.full.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - **Background**: Repeat offending, also known as criminal recidivism, in people released from prison has remained high over many decades. To address this, psychological treatments have been increasingly used in criminal justice settings; however, there is little evidence about their effectiveness. We aimed to evaluate the effectiveness of interventions in prison to reduce recidivism after release. 

**Method(s)**: For this systematic review and meta-analysis, we searched the Cochrane Central Register of Controlled Trials, Embase, Global Health, MEDLINE, PsycINFO, and Google Scholar for articles published from database inception to Feb 17, 2021, without any language restrictions. We searched for randomised controlled trials (RCTs) that evaluated the effect of psychological interventions, delivered to adolescents and adults during incarceration, on recidivism outcomes after release. We excluded studies of solely pharmacological interventions and of participants in secure psychiatric hospitals or special residential units, or attending therapies mainly delivered outside of the prison setting. We extracted summary estimates from eligible RCTs. Data were extracted and appraised according to a prespecified protocol, with effect sizes converted to odds ratios. We used a standardised form to extract the effects of interventions on recidivism and estimated risk of bias for each RCT. Planned sensitivity analyses were done by removing studies with fewer than 50 participants. Our primary outcome was recidivism. Data from individual RCTs were combined in a random-effects meta-analysis as pooled odds ratios (ORs) and we explored sources of heterogeneity by comparing effect sizes by study size, control group, and intervention type. The protocol was pre-registered with PROSPERO, CRD42020167228. 

**Finding(s)**: Of 6345 articles retrieved, 29 RCTs (9443 participants, 1104 [11.7%] females, 8111 [85.9%] males, and 228 [2.4%] unknown) met the inclusion criteria for the primary outcome. Mean ages were 31.4 years (SD 4.9, range 24.5-41.5) for adult participants and 17.5 years (SD 1.9; range 14.6-20.2) for adolescent participants. Race or ethnicity data were not sufficiently reported to be aggregated. If including all 29 RCTs, psychological interventions were associated with reduced reoffending outcomes (OR 0.72, 95% CI 0.56-0.92). However, after excluding smaller studies (&lt;50 participants in the intervention group), there was no significant reduction in recidivism (OR 0.87, 95% CI 0.68-1.11). Based on two studies, therapeutic communities were associated with decreased rates of recidivism (OR 0.64, 95% CI 0.46-0.91). These risk estimates did not significantly differ by type of control group and other study characteristics. Interpretation(s): Widely implemented psychological interventions for people in prison to reduce offending after release need improvement. Publication bias and small-study effects appear to have overestimated the reported modest effects of such interventions, which were no longer present when only larger studies were included in analyses. Findings suggest that therapeutic communities and interventions that ensure continuity of care in community settings should be prioritised for future research. Developing new treatments should focus on addressing modifiable risk factors for reoffending. Funding(s): Wellcome Trust, Fonds de recherche du Quebec - Sante. Copyright &copy; 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license
AN  - 2014134344
AU  - Beaudry,
AU  - G.
AU  - Yu,
AU  - R.
AU  - Perry,
AU  - A.
AU  - E.
AU  - Fazel,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/S2215-0366%2821%2900170-X
L1  - internal-pdf://4225114857/Beaudry-2021-Effectiveness of psychological in.pdf
PY  - 2021
SP  - 759-773
T2  - The Lancet Psychiatry
TI  - Effectiveness of psychological interventions in prison to reduce recidivism: a systematic review and meta-analysis of randomised controlled trials
UR  - https://www.journals.elsevier.com/the-lancet-psychiatry
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376657/pdf/main.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **Background**: Over 250 million children in low- and middle-income countries are at risk of not achieving their fullest developmental potential due to co-occurring risks such as poor nutrition and inadequate learning opportunities. Early intervention programs integrating the aspects of nurturing care, that is, good health, adequate nutrition, safety and security, responsive caregiving, and learning opportunities, may ameliorate against the negative impact of these adverse conditions. 

**Methods**: This meta-analytic review updates the evidence base of parenting interventions comprising stimulation and responsive caregiving components on developmental outcomes for children under age 2 years in low- and middle-income countries. It also describes and assesses the moderation effects of population characteristics and implementation features on the intervention effectiveness. Studies were identified based on previous systematic reviews and an updated literature search in eight databases and the gray literature up to December 2020. A random-effect model was used to explore the pooled effect sizes accounted for by the intervention for developmental outcome of cognition, language, motor, and social-emotional capacities. Exploratory moderation analyses were also conducted. 

**Results**: Twenty-one randomized controlled trials representing over 10,400 children from 12 low- and middle-income countries and regions across three continents (Africa, Latin America, and Asia) were identified. The interventions showed overall small-to-moderate effects on children&#039;s cognitive development (ES = 0.44; 95% CI = [0.30, 0.57]); language development (ES = 0.33; 95% CI = [0.18, 0.49]); and motor skills (ES = 0.21; 95% CI = [0.10, 0.32]). The overall effect on social-emotional development was non-significant (ES = 0.17; 95% CI = [-0.01, 0.34]). Effect sizes (ES) varied significantly across the studies. Parenting programs that targeted vulnerable groups, including rural communities and caregivers with lower education levels, had more significant effects on children&#039;s development. Group sessions (vs. individual visits) and high program dose (&gt;= 12 sessions) were also associated with stronger effects on child development. Further research is needed to determine the effectiveness of the workforce and training on programmatic outcomes. 

**Conclusion**: The findings indicate that parenting interventions that encourage nurturing care are effective in improving the early development of children, especially among vulnerable populations. We discuss opportunities to strengthen the implementation of research-based parenting interventions in such contexts.
AN  - WOS:000679857500001
AU  - Zhang,
AU  - L.
AU  - L.
AU  - Ssewanyana,
AU  - D.
AU  - Martin,
AU  - M.
AU  - C.
AU  - Lye,
AU  - S.
AU  - Moran,
AU  - G.
AU  - Abubakar,
AU  - A.
AU  - Marfo,
AU  - K.
AU  - Marangu,
AU  - J.
AU  - Proulx,
AU  - K.
AU  - Malti,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpubh.2021.671988
L1  - internal-pdf://1443362570/Zhang-2021-Supporting Child Development Throug.pdf
PY  - 2021
SP  - 20
T2  - Frontiers in Public Health
TI  - Supporting Child Development Through Parenting Interventions in Low- to Middle-Income Countries: An Updated Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000679857500001
VL  - 9
ER  -
TY  - JOUR
AB  - The authors conducted a meta-analysis exploring the effectiveness of child-centered play therapy (CCPT) approaches with children referred for disruptive behaviors across 23 between group studies (N = 908). Separate meta-analytic procedures were conducted for studies that implemented wait-list/no treatment and alternative treatment comparisons to estimate the aggregated treatment effect of CCPT approaches. Results revealed medium Hedges&#039;s g effect sizes for externalizing and overall problem behaviors compared to alternative treatment and waitlist controls, and small Hedges&#039;s g effect sizes for aggressive behaviors. The authors explore the impact of CCPT on behavioral disruptions, implications for therapists, and ways in which therapists can utilize play therapy to meet the increasing rates of childhood behavioral disorders. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-70169-001
AU  - Parker,
AU  - M.
AU  - M.
AU  - Hunnicutt
AU  - Hollenbaugh,
AU  - K.
AU  - Kelly,
AU  - C.
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/pla0000128
L1  - internal-pdf://3094234344/Parker-2021-Exploring the impact of child-cent.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - International Journal of Play Therapy
TI  - Exploring the impact of child-centered play therapy for children exhibiting behavioral problems: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-70169-001
ER  -
TY  - JOUR
AB  - **Introduction** Inadequate care during early childhood can lead to long-term deficits in skills. Parenting programmes that encourage investment in young children are a promising tool for improving early development outcomes and long-term opportunities in low-income and middle-income regions, such as rural China. 

**Methods** We conducted a systematic review and a meta-analysis to investigate the prevalence of early developmental delays and stimulating parenting practices as well as the effect of parental training programmes on child development outcomes in rural China. We obtained data in English from EconPapers, PubMed, PsycARTICLES, Cochrane Library, Web of Science and Scopus (Elsevier) and in Chinese from China National Knowledge Infrastructure, Wanfang Data and VIP Information. We conducted frequentist meta-analyses of aggregate data and estimated random-effects meta-regressions. Certainty of evidence was rated according to the Grading of Recommendations Assessment, Development and Evaluation approach. 

**Results** We identified 19 observational studies on the prevalence of developmental delays and stimulating parenting practices for children under 5 years of age (n=19 762) and ten studies on the impact of parental training programmes on early child development (n=13 766). Children&#039;s risk of cognitive, language and social-emotional delays in the rural study sites (covering 14 provinces mostly in Central and Western China) was 45%, 46%, and 36%, respectively. Parental training programmes had a positive impact on child cognition, language and social-emotional development. 

**Conclusion** There is evidence to suggest that early developmental delay and the absence of stimulating parenting practices (ie, reading, storytelling and singing with children) may be prevalent across rural, low-income and middle-income regions in Central and Western China. Results support the effectiveness of parental training programmes to improve early development by encouraging parental engagement.
AN  - WOS:000687755100003
AU  - Emmers,
AU  - D.
AU  - Jiang,
AU  - Q.
AU  - Xue,
AU  - H.
AU  - Zhang,
AU  - Y.
AU  - Zhang,
AU  - Y.
AU  - T.
AU  - Zhao,
AU  - Y.
AU  - X.
AU  - Liu,
AU  - B.
AU  - Dill,
AU  - S.
AU  - E.
AU  - Qian,
AU  - Y.
AU  - W.
AU  - Warrinnier,
AU  - N.
AU  - Johnstone,
AU  - H.
AU  - Cai,
AU  - J.
AU  - H.
AU  - Wang,
AU  - X.
AU  - L.
AU  - Wang,
AU  - L.
AU  - Luo,
AU  - R.
AU  - F.
AU  - Li,
AU  - G.
AU  - R.
AU  - Xu,
AU  - J.
AU  - J.
AU  - Liu,
AU  - M.
AU  - Huang,
AU  - Y.
AU  - Q.
AU  - Shan,
AU  - W.
AU  - J.
AU  - Li,
AU  - Z.
AU  - H.
AU  - Zhang,
AU  - Y.
AU  - Sylvia,
AU  - S.
AU  - Ma,
AU  - Y.
AU  - Medina,
AU  - A.
AU  - Rozelle,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/bmjgh-2021-005578
L1  - internal-pdf://3875418495/Emmers-2021-Early childhood development and pa.pdf
PY  - 2021
SP  - 13
T2  - Bmj Global Health
TI  - Early childhood development and parental training interventions in rural China: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000687755100003
UR  - https://gh.bmj.com/content/bmjgh/6/8/e005578.full.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **Objectives** Low-income youth are at greater risk for persistent exposure to environmental stressors and they face a number of barriers to accessing mental health treatment. Furthermore, it is unclear whether interventions developed for youth more generally are effective for this vulnerable population. The objective of this systematic review was to review and summarize the effectiveness of mindfulness-based interventions delivered in low-income schools (Grades 3-9) on psychological functioning. 

**Methods** Searches were conducted in PsycINFO, Web of Science, PubMed, Scopus, and MEDLINE, which led to the inclusion of eight studies in the current review (seven unique samples). Study interventions, methodologies, and individual characteristics were reviewed and summarized. 

**Results** Findings were inconsistent across studies, but some improvements were reported for externalizing and internalizing symptoms, emotional regulation, and perceived stress. Feasibility data were limited, with findings of high enrollment and retention, moderate levels of student-reported satisfaction, and low adherence to at-home practice. 

**Conclusions** Although diverse interventions were delivered across studies, these results suggest that school-based mindfulness interventions may have potential for increasing access to intervention for low-income youth. Strengths and limitations of the literature are reviewed, and future directions are discussed.
AN  - WOS:000605092800002
AU  - Segal,
AU  - S.
AU  - C.
AU  - Vyas,
AU  - S.
AU  - S.
AU  - Monson,
AU  - C.
AU  - M.
DA  - JUN
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12671-020-01571-8
L1  - internal-pdf://2312243589/Segal-2021.pdf
PY  - 2021
SP  - 1316-1331
T2  - MINDFULNESS
TI  - A Systematic Review of Mindfulness-Based Interventions in Low-Income Schools
UR  - https://link.springer.com/content/pdf/10.1007/s12671-020-01571-8.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **Background** Universal classroom-based interventions are a useful method to increase the mental health and resilience in children. Resilience describes the process that leads to a positive development despite adversities. It comprises the seven resources access to material resources, relationships, identity, power and control, cultural adherence, social justice and cohesion. Yet there is a paucity of studies evaluating interventions that enhance resilience in children exposed to adverse childhood experiences.

**Method** This systematic review investigates whether universal classroom-based interventions can increase the seven resilience-related resources in children that live in adverse environments. Search strings were formulated based on an adapted version of the PICO criteria. The risk of bias of the individual studies was assessed using the ROBINS-I tool. 

**Results** Seventeen studies were included in the review, of which 15 found an increase in resilience. The resource power and control was targeted in every intervention. Not one intervention included all seven resources. Intervention outcomes related mostly to just two of the resources (power and control and identity) and were rarely linked to what was being trained in the intervention. 

**Conclusion** The results of this review show that classroom-based interventions are suitable for promoting resilience in children living in adverse environments. Yet more high-quality studies are needed that evaluate the effectiveness of universal interventions on children living in adverse environments and specifically the effectiveness of training each of the seven resources. Future developments of school-based interventions should be careful to target and assess all resilience-related resources.
AN  - WOS:000679304600001
AU  - Higgen,
AU  - S.
AU  - Mueller,
AU  - J.
AU  - T.
AU  - Mosko,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/camh.12493
L1  - internal-pdf://4229408502/Higgen-Review_ Universal mental health interve.pdf
PY  - 2021
SP  - 13
T2  - Child and Adolescent Mental Health
TI  - Review: Universal mental health interventions for young students in adverse environments - a systematic review of evaluated interventions
UR  - &lt;Go to ISI&gt;://WOS:000679304600001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/camh.12493?download=true
ER  -
TY  - JOUR
AB  - AIM: To date it is unclear whether the physical, cognitive, psychological and social benefits of dance extend to children with disabilities.

METHOD: This systematic review synthesised empirical research on the effect of non-therapy dance programs on children with physical and developmental disabilities.

RESULTS: Nineteen studies met inclusion criteria, including 521 participants aged 3-18 years and adapted dance programs with duration ranging from 7-78 hours. Sixteen studies had weak methodology. Most examined physical outcomes with improvements in 17/23 areas and meta-analyses showing significant medium to large effects for balance and jumping skills. Positive effects were also indicated for psychological, cognitive and social domains from the few available studies.

CONCLUSION: Existing literature is heterogeneous and of poor quality but indicates dance may have physical, cognitive and psychosocial benefits for children with disabilities. Implications for rehabilitation To date the benefits of dance for children with disabilities have not been systematically synthesised. Dance may have physical, cognitive and psychosocial benefits for children with disabilities. Further research into psychosocial benefits in particular is warranted.
AD  - May, Tamara. Deakin Child Study Centre, School of Psychology, Deakin University, Geelong, Australia.Chan, Emily S. Deakin Child Study Centre, School of Psychology, Deakin University, Geelong, Australia.Lindor, Ebony. Deakin Child Study Centre, School of Psychology, Deakin University, Geelong, Australia.McGinley, Jennifer. Department of Physiotherapy, University of Melbourne, Parkville, Australia.Skouteris, Helen. Monash Centre for Healthcare Improvement and Implementation Science, Monash University, Clayton, Australia.Austin, David. Deakin Child Study Centre, School of Psychology, Deakin University, Geelong, Australia.McGillivray, Jane. Deakin Child Study Centre, School of Psychology, Deakin University, Geelong, Australia.Rinehart, Nicole J. Deakin Child Study Centre, School of Psychology, Deakin University, Geelong, Australia.
AN  - 31112671
AU  - May,
AU  - T.
AU  - Chan,
AU  - E.
AU  - S.
AU  - Lindor,
AU  - E.
AU  - McGinley,
AU  - J.
AU  - Skouteris,
AU  - H.
AU  - Austin,
AU  - D.
AU  - McGillivray,
AU  - J.
AU  - Rinehart,
AU  - N.
AU  - J.
DA  - Jan
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/09638288.2019.1615139
DP  - Ovid Technologies
J2  - Disabil Rehabil
L1  - internal-pdf://2108532322/May-2021.pdf
LA  - English
N1  - May, TamaraChan, Emily SLindor, EbonyMcGinley, JenniferSkouteris, HelenAustin, DavidMcGillivray, JaneRinehart, Nicole J
PY  - 2021
SP  - 13-26
T2  - Disability &amp; Rehabilitation
TI  - Physical, cognitive, psychological and social effects of dance in children with disabilities: systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31112671
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31112671&amp;id=doi:10.1080%2F09638288.2019.1615139&amp;issn=0963-8288&amp;isbn=&amp;volume=43&amp;issue=1&amp;spage=13&amp;pages=13-26&amp;date=2021&amp;title=Disability+%26+Rehabilitation&amp;atitle=Physical%2C+cognitive%2C+psychological+and+social+effects+of+dance+in+children+with+disabilities%3A+systematic+review+and+meta-analysis.&amp;aulast=May&amp;pid=%3Cauthor%3EMay+T%3C%2Fauthor%3E%3CAN%3E31112671%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/full/10.1080/09638288.2019.1615139
UR  - https://www.tandfonline.com/doi/pdf/10.1080/09638288.2019.1615139?needAccess=true
VL  - 43
ER  -
TY  - JOUR
AB  - **Purpose**: This systematic review critically appraises and maps the evidence for stuttering interventions in childhood and adolescence. We examine the effectiveness of speech-focused treatments, the efficacy of alternative treatment delivery methods and identify gaps in the research evidence. 

**Method(s)**: Nine electronic databases and three clinical trial registries were searched for systematic reviews, randomised controlled trials (RCTs) and studies that applied an intervention with children (2-18 years) who stutter. Pharmacological interventions were excluded. Primary outcomes were a measure of stuttering severity and quality assessments were conducted on all included studies. 

**Result(s)**: Eight RCTs met inclusion criteria and were analysed. Intervention approaches included direct (i.e. Lidcombe Program; LP) and indirect treatments (e.g. Demands and Capacities Model; DCM). All studies had moderate risk of bias. Treatment delivery methods included individual face-to-face, telehealth and group-based therapy. Both LP and DCM approaches were effective in reducing stuttering in preschool aged children. LP had the highest level of evidence (pooled effect size=-3.8, CI -7.3 to -0.3 for LP). There was no high-level evidence for interventions with school-aged children or adolescents. Alternative methods of delivery were as effective as individual face-to-face intervention. 

**Conclusion(s)**: The findings of this systematic review and evidence mapping are useful for clinicians, researchers and service providers seeking to understand the existing research to support the advancement of interventions for children and adolescence who stutter. Findings could be used to inform further research and support clinical decision-making. Copyright &copy; 2021 Elsevier Inc.
AN  - 2011401305
AU  - Brignell,
AU  - A.
AU  - Krahe,
AU  - M.
AU  - Downes,
AU  - M.
AU  - Kefalianos,
AU  - E.
AU  - Reilly,
AU  - S.
AU  - Morgan,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jfludis.2021.105843
L1  - internal-pdf://0516906955/Brignell-2021-Interventions for children and a.pdf
PY  - 2021
T2  - Journal of Fluency Disorders
TI  - Interventions for children and adolescence who stutter: A systematic review, meta-analysis, and evidence map
UR  - http://www.elsevier.com/locate/jfludis
VL  - 70 (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND**: There is a growing interest in the promotion of mental health, and concepts as resilience are re-emerging and taking relevance. In addition, Information and Communication Technologies can provide potential benefits in the field of mental health, and the treatment of mental disorders in particular. This study aims to synthesize the evidence of internet-based resilience interventions, analyzing the theoretical adequacy, methodological quality and efficacy. 

**METHODS**: A systematic search was performed. The eligibility criteria stated for this article were: randomized controlled trials targeted at adults or adolescents and including any psychological intervention focussing on resilience in its rationale or design. Studies with direct (e.g. resilience scales) and proximal resilience measures (e.g. scales on well-being) were included. Risk of bias was assessed for each trial using Cochrane&#039;s Collaboration Tool. Two reviewers worked independently in order to identify potential articles. A total of 11 articles were selected. A random-effects pooling model using the Hartung-Knapp-Sidik-Jonkman method based on direct and proximal resilience measures at post-test was used. 

**RESULTS**: The overall effects of online resilience training compared to control groups at post-test were not significant; the effect size concerning the improvement of resilience was g=0.12 (95% CI: -0.14 to 0.38). In addition, a potential association between the type of outcome and the effect size could be revealed. 

**CONCLUSIONS**: The results of the present meta-analysis showed that the overall effect of online resilience trainings was not significant. Nonetheless, a tendency for a higher benefit for resilience was found in the studies with a clear assessment theory, indicating some promising effects. Registration number: Prospero crd42018083339.
AN  - 34240159
AU  - Diaz-Garcia,
AU  - A.
AU  - Franke,
AU  - M.
AU  - Herrero,
AU  - R.
AU  - Ebert,
AU  - D.
AU  - D.
AU  - Botella,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/eurpub/ckaa255
L1  - internal-pdf://1101430805/Diaz-Garcia-2021-Theoretical adequacy, methodo.pdf
PY  - 2021
SP  - i11-i18
T2  - European Journal of Public Health
TI  - Theoretical adequacy, methodological quality and efficacy of online interventions targeting resilience: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34240159
UR  - https://watermark.silverchair.com/ckaa255.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAt4wggLaBgkqhkiG9w0BBwagggLLMIICxwIBADCCAsAGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMMiT6ZB7vEiN3L1MkAgEQgIICkTkwyO7292fnYDrN1SBGAEG-w4E_BuYVw_RwlW28Ih6Ga6hVb-nSATznaXTypTkszxeyhi7PVrbHnwvLVQVUTTuxLPpqJ853UZuwpXIck6FW4cyBnhT-rfXIT2XM1u2_FIu97odcTAq5zUmk9tAChfG1f-paDoA46urN7KEFJPP3Ll1SfEDw6U3ZhJkkRgkBUo6JfRT9DnDkoA6Y63XPa7h0Vg-67vk2zAiooj31O17eK7-7XinAelJLa34xR6ppQKfPwx5f1h9vUv0yMC9H-F3uJNHhImbRmjuXo_yxZV3CnUQ_Ua3N9hETxD0wt-funsV9guaS100SnkUYdfAG2GuTANS7zHIzTt-63TfIYOWx_WS9saTmRPn8gDRst6tcg8W3ILS9EaOH6NMLTYARPSkfwyVyso8bttzIC_yTgLhVBiFweRnQgnfXU1CPx8uUupbKjvi8ew_vx9qy70JXqAfQL-pNNVw2FHnQh4ytgRdwBSjspQsk6OuJAUbxaNbGuhAQiuzYT_FcEjKmx5Jz3dYG6LkIFe0wEtM34YW1APsRzDJwzALxt7PajTgBSkQeN993HDzVNWFIm0d9I9jP2_mx3QkEQ23dpk_2aarYuARUYQrr68Zx1y3nF7JLavyHfWwOTQ2VPdx7wApr4fleUSH05sJwKXlB72UEN0v9LKETzfbFAQOK1-V1On5FGV2O1N3u8Wcd_ZCgzhwHUxfsAfel8j7Y86JlogIhYoUotZjQxaB37RKa2mvry9zF8lrSSjULfhbWH7VNZ_0E8_OUhu8m4re1VIU8HZrT_7s8xAt06B41k7wwYQITLG1W4ptMj2vD5YF-_5zXmb6l6I71otS6ay-uz6eVcZML4nMBbo5lpQ
VL  - 31
ER  -
TY  - JOUR
AB  - **Background**: Nocturnal crying is a common condition in which children intermittently or continuously cry and fuss during the night, at certain times or throughout the night. It is a common pediatric sleep disturbance for which medical assistance is highly sought by parents, and one of the non-pharmacologic treatments for nocturnal crying is pediatric acupuncture. This review aimed to review the literature about the effectiveness and safety of pediatric acupuncture for nocturnal crying. 

**Methods**: Literature searches were performed on PubMed, the Cochrane Controlled Register of Trials (CENTRAL), Allied and Complementary Medicine Database (AMED), Chinese National Knowledge Infrastructure Database (CNKI), Wanfang Database, and Chinese Science and Technique Journals Database (VIP), OASIS, the Research Information Service System (RISS), and National Digital Science Library (NDSL) from the available date of inception until December 28, 2020. Two review authors independently screened the titles and abstracts of all relevant articles from the search to select eligible articles. All variants of clinical studies on acupuncture treatment for nocturnal crying, including case reports and case studies, were eligible. Data were independently extracted by two review authors using a standard data extraction form. Retrieved data are presented in a tabular form and narratively discussed.

**Results**: We included 12 studies (10 case series and two case reports) with a total sample size of 2,324 children recruited from the hospital outpatient department. All of the included studies were conducted in mainland China and administered acupuncture as the sole intervention. For the primary outcome, the total efficacy rate of acupuncture treatment for nocturnal crying was reported as 100% in 9 studies, 95% in one study, 94% in another study, and 86% in the remaining study. For the secondary outcome, one study reported a 14% recurrence rate, whereas another study reported an 11% recurrence rate after treatment. There were no follow-ups in most of the studies. None of the studies reported possible adverse events. Most children recovered after one treatment. Generally, the acupoints that were most frequently selected were acupoints EM30 and PC9. 

**Conclusions**: This comprehensive review suggested that pediatric acupuncture may be an effective treatment for nocturnal crying, which could be worth investigating further.
AN  - WOS:000679061600001
AU  - Ang,
AU  - L.
AU  - Song,
AU  - E.
AU  - Lee,
AU  - H.
AU  - W.
AU  - Kim,
AU  - J.
AU  - T.
AU  - Kim,
AU  - E.
AU  - Lee,
AU  - M.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fped.2021.647098
L1  - internal-pdf://3353365649/Ang-2021-Acupuncture Treatment for Nocturnal C.pdf
PY  - 2021
SP  - 8
T2  - Frontiers in Pediatrics
TI  - Acupuncture Treatment for Nocturnal Crying in Pediatric Patients: A Systematic Review of Clinical Studies
UR  - &lt;Go to ISI&gt;://WOS:000679061600001
VL  - 9
ER  -
TY  - JOUR
AB  - The Good Behavior Game (GBG) is widely recognized as an evidence-based intervention that reinforces prosocial behaviors and discourages disruptive behaviors among students in the classroom setting. 

The current meta-analysis synthesized randomized controlled trials of the GBG to examine its impact on proximal student outcomes across seven studies representing 4,700 children. Although recent reviews focusing on single-case studies of the GBG have reported moderate to large treatment effects, our results were quite modest in comparison (hedges&#039; g = 0.09-0.32). 

Treatment effect sizes also varied according to outcome and sex. The GBG significantly outperformed the comparison conditions for peer-rated conduct problems and shy/withdrawn behavior as well as teacher-rated conduct problems for which a greater effect was found for girls relative to boys. Moreover, the treatment effect in favor of the GBG for reading comprehension was specific to boys and not girls. 

No significant differences were found between the GBG and comparison conditions for inattention and teacher-rated shy/withdrawn behavior. These results suggest that the GBG may not be as impactful as originally reported and the intended population and treatment targets should be considered before its implementation in the classroom. 

(PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-71945-006
AU  - Smith,
AU  - S.
AU  - Barajas,
AU  - K.
AU  - Ellis,
AU  - B.
AU  - Moore,
AU  - C.
AU  - McCauley,
AU  - S.
AU  - Reichow,
AU  - B.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/0145445519878670
L1  - internal-pdf://2761833384/Smith-2021-A meta-analytic review of randomize.pdf
PY  - 2021
SP  - 641-666
T2  - Behavior Modification
TI  - A meta-analytic review of randomized controlled trials of the Good Behavior Game
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-71945-006
UR  - https://journals.sagepub.com/doi/10.1177/0145445519878670?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0145445519878670
VL  - 45
ER  -
TY  - JOUR
AB  - With a mandate to increase the capacity to support global mental health, this is the first meta-analysis with the aim of examining where the field stands in understanding the effectiveness of psychological interventions created for, and implemented with, children in African countries who experience stress and trauma. Searches for empirical randomized-controlled trials of psychological interventions with children in African countries were carried out in major databases. 

The current study combines the results of 26 studies to examine overall effectiveness of these interventions and goes on to examine the moderators of effectiveness looking at eight different potential moderators. Two moderators reach the level of significance, namely that mental health outcomes and age moderate the effectiveness of an intervention. Interventions targeting trauma were most effective. Some instances in which the null hypothesis could not be rejected turned out to be positive for the purposes of this study e.g. the education level of facilitators and the format of the group, do not show a significant impact on the effect size of these interventions. 

This study concludes that the creation and development of psychological interventions for African children should continue, and potential moderating variables should be more closely examined.
AN  - WOS:000669841300002
AU  - Katsonga-Phiri,
AU  - T.
AU  - Lewis,
AU  - J.
AU  - T.
AU  - Murray,
AU  - M.
AU  - DuBois,
AU  - D.
AU  - L.
AU  - Grant,
AU  - K.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.childyouth.2021.106096
L1  - internal-pdf://1307095335/Katsonga-Phiri-2021-Mental health intervention.pdf
PY  - 2021
SP  - 13
T2  - Children and Youth Services Review
TI  - Mental health interventions for African children: A meta-analytic review
UR  - &lt;Go to ISI&gt;://WOS:000669841300002
VL  - 127
ER  -
TY  - JOUR
AB  - Depression is a disabling, highly prevalent, frequently chronic, and difficult-to-treat disorder with an immense cognitive, social, and economic burden. Given that many of the advances in other non-communicable disorders like cancer have been in prevention rather than treatment, the prevention of depression is currently an unmet public health priority. 

We sought to provide an overview of the meta-analytic literature through conducting a systematic umbrella review of universally delivered preventive interventions for depression. The search was conducted on March 18, 2021 utilising the following databases (all accessed through EBSCOHost); Allied and Complementary Medicine Database, CINAHL Complete, Global Health, Health Source: Nursing/Academic Edition, MEDLINE Complete and APA PsychArticles. The following search terms related to depression, prevention, and trial study design. Two authors independently screened articles and a third resolved discrepancies. Eligibility criteria sought to identify meta-analyses that investigated the prevention of depression (i.e., reduced incidence) through intervention studies that were universal, in that they were designed to be delivered to entire populations.

Six meta-analyses on psychological interventions, two school-based meta-analyses, and one eHealth meta-analysis were included in this umbrella review. Findings indicated that all identified studies were of good quality and one was of fair quality. One previous meta-review that examined physical activity to prevent depression was included in results, comprising eight meta-analyses. Preventive interventions have primarily and successfully utilized psychological therapeutic components, delivered at the school, community, and workplace settings. Both school- and eHealth-based interventions hold some utility for depression prevention. 

There is meta-analytic evidence that physical activity is efficacious for depression prevention. However, universal prevention is inconsistently defined. There is a pressing need for well-designed randomized controlled preventative interventions for depression before recommendations can be universally accepted with convincing level of evidence. Copyright &copy; 2021
AN  - 2015489107
AU  - Hoare,
AU  - E.
AU  - Collins,
AU  - S.
AU  - Marx,
AU  - W.
AU  - Callaly,
AU  - E.
AU  - Moxham-Smith,
AU  - R.
AU  - Cuijpers,
AU  - P.
AU  - Holte,
AU  - A.
AU  - Nierenberg,
AU  - A.
AU  - A.
AU  - Reavley,
AU  - N.
AU  - Christensen,
AU  - H.
AU  - Reynolds,
AU  - C.
AU  - F.
AU  - Carvalho,
AU  - A.
AU  - F.
AU  - Jacka,
AU  - F.
AU  - Berk,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jpsychires.2021.10.006
L1  - internal-pdf://3813127473/Hoare-2021.pdf
PY  - 2021
SP  - 483-493
T2  - Journal of Psychiatric Research
TI  - Universal depression prevention: An umbrella review of meta-analyses
UR  - http://www.elsevier.com/locate/jpsychires
UR  - https://www.sciencedirect.com/science/article/abs/pii/S002239562100604X?via%3Dihub
VL  - 144
ER  -
TY  - JOUR
AB  - Background: Progesterone is widely used in prenatal care. However, long-term effects of prenatal progesterone treatment on child development are unclear. Objective(s): To evaluate long-term outcomes in children after prenatal progesterone treatment. Search strategy: MEDLINE, Embase and Cochrane Central Register of Controlled Trials from inception to 24 May 2020. Selection Criteria: Randomised controlled trials (RCTs) reporting outcomes in children born to women who received progesterone treatment (compared with placebo or another intervention) during any trimester in pregnancy. Data Collection and Analysis: Two authors independently selected and extracted data. We used the Cochrane Risk of Bias tool for randomised trials and Quality In Prognosis Studies. Main Result(s): Of 388 papers, we included seven articles based on five RCTs, comprising 4222 measurements of children aged 6 months to 8 years. All studies compared progesterone to placebo in second and/or third trimester for the prevention of preterm birth. Meta-analysis (two studies, n = 890 children) showed no difference in neurodevelopment as assessed by the Bayley-III Cognitive Composite score at 2 years between children exposed to progesterone versus placebo (Standardised Mean Difference -0.04, 95% Confidence Interval -0.26 to 0.19), I&lt;sup&gt;2&lt;/sup&gt; = 22%. Heterogeneity prohibited additional meta-analyses. Other long-term outcomes showed no differences. Conclusion(s): Our systematic review comprising a multitude of developmental measurements with a broad age range did not find evidence of benefit or harm in offspring prenatally exposed to progesterone treatment for the prevention of preterm birth. We identified an urgent need for follow-up studies of prenatal progesterone administration in early pregnancy and effects in offspring beyond early childhood. Tweetable abstract: Progesterone to prevent preterm birth: no effect on child development. Outcomes after first trimester progesterone are unclear. Copyright &copy; 2020 The Authors. BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley &amp; Sons Ltd
AD  - (Simons, Leeuw, van&#039;t Hooft, Roseboom, Oudijk, Pajkrt, Painter) Department of Obstetrics, Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands (Limpens) Medical Library, Research Support, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands (Roseboom) Department of Epidemiology and Data Science, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands (Finken) Department of Paediatric Endocrinology, Emma Children&#039;s Hospital, Amsterdam UMC, Amsterdam, NetherlandsN.E. Simons, Department of Obstetrics, Amsterdam Reproduction and Development Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands. E-mail: n.e.simons@amsterdamumc.nl
AN  - 2007461061
AU  - Simons,
AU  - N.
AU  - E.
AU  - Leeuw,
AU  - M.
AU  - van&#039;t
AU  - Hooft,
AU  - J.
AU  - Limpens,
AU  - J.
AU  - Roseboom,
AU  - T.
AU  - J.
AU  - Oudijk,
AU  - M.
AU  - A.
AU  - Pajkrt,
AU  - E.
AU  - Finken,
AU  - M.
AU  - J.
AU  - J.
AU  - Painter,
AU  - R.
AU  - C.
DA  - May
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/1471-0528.16582
DP  - Ovid Technologies
KW  - Development
KW  - Follow up
KW  - long-term
KW  - luteal phase support
KW  - preterm birth prevention
KW  - progesterone
KW  - systematic review
KW  - Bayley Scales of Infant Development
KW  - child
KW  - child development
KW  - childhood
KW  - clinical trial
KW  - Cochrane Library
KW  - controlled study
KW  - drug therapy
KW  - Embase
KW  - female
KW  - first trimester pregnancy
KW  - human
KW  - infant
KW  - luteal phase
KW  - Medline
KW  - meta analysis
KW  - nervous system development
KW  - nonhuman
KW  - prematurity
KW  - prevention
KW  - progeny
KW  - prognosis
KW  - randomized controlled trial (topic)
KW  - review
KW  - school child
KW  - third trimester pregnancy
KW  - placebo
L1  - internal-pdf://3336911738/Simons-2021.pdf
LA  - English
M3  - Review
PY  - 2021
SP  - 964-974
T2  - BJOG: An International Journal of Obstetrics and Gynaecology
TI  - The long-term effect of prenatal progesterone treatment on child development, behaviour and health: a systematic review
UR  - http://obgyn.onlinelibrary.wiley.com/hub/journal/10.1111/(ISSN)1471-0528/
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2007461061
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33112462&amp;id=doi:10.1111%2F1471-0528.16582&amp;issn=1470-0328&amp;isbn=&amp;volume=128&amp;issue=6&amp;spage=964&amp;pages=964-974&amp;date=2021&amp;title=BJOG%3A+An+International+Journal+of+Obstetrics+and+Gynaecology&amp;atitle=The+long-term+effect+of+prenatal+progesterone+treatment+on+child+development%2C+behaviour+and+health%3A+a+systematic+review&amp;aulast=Simons&amp;pid=%3Cauthor%3ESimons+N.E.%3C%2Fauthor%3E%3CAN%3E2007461061%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://obgyn.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/1471-0528.16582?download=true
VL  - 128
ER  -
TY  - JOUR
AB  - **Background**: Pediatric, adolescent, and young adult (PAYA) cancer survivors suffer from multiple domains of adverse psychosocial and behavioral outcomes during and after their cancer treatment. This study conducted a systematic review and metaanalysis of psychosocial, behavioral, and supportive interventions for PAYA cancer survivors. 

**Method(s)**: We searched 11 electronic databases, 4 professional websites, and manual search of reference lists in existing reviews. We selected randomized controlled trials and controlled trials without randomization focusing on PAYA cancer survivors across six outcome domains. 

**Result(s)**: We included 61 studies (4,402 participants) published between 1987 and 2020. Overall risk of bias across studies was low. We identified an overall moderate and statistically significant treatment effect size for PAYA cancer survivors across six outcome domains. 

**Conclusion(s)**: psychosocial, behavioral, and supportive interventions were overall effective for PAYA cancer survivors. However, interventions were not effective for certain outcome domains, and less effective among AYA versus pediatric cancer survivors. Copyright &copy; 2021 Elsevier B.V.
AD  - (Zhang, Zebrack) University of Michigan School of Social Work, United States (Wang) University of Denver Graduate School of Social Work, United States (Tan) University of Michigan Medical School Department of Psychiatry, United States (Walling) University of Michigan Medical School Department of Pediatrics, United States (Chugh) University of Michigan Medical School Department of Internal Medicine, United StatesA. Zhang, Adolescent and Young Adult Oncology Program at Michigan Medicine, RM3704 1080 South University Avenue, Ann Arbor, MI 48109, United States. E-mail: zhangan@umich.edu
AN  - 2011292952
AU  - Zhang,
AU  - A.
AU  - Wang,
AU  - K.
AU  - Zebrack,
AU  - B.
AU  - Tan,
AU  - C.
AU  - Y.
AU  - Walling,
AU  - E.
AU  - Chugh,
AU  - R.
DA  - April
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.critrevonc.2021.103291
DP  - Ovid Technologies
KW  - Adolescent and young adult cancer
KW  - Pediatric cancer
KW  - Psycho-oncology
KW  - Survivorship
KW  - Systematic review and meta-analysis
KW  - adolescent
KW  - adult
KW  - cancer survival
KW  - cancer survivor
KW  - child
KW  - effect size
KW  - female
KW  - human
KW  - human experiment
KW  - male
KW  - meta analysis
KW  - randomization
KW  - randomized controlled trial (topic)
KW  - review
KW  - systematic review
KW  - young adult
L1  - internal-pdf://1098719640/Zhang-2021.pdf
LA  - English
M3  - Review
PY  - 2021
T2  - Critical Reviews in Oncology/Hematology
TI  - Psychosocial, behavioral, and supportive interventions for pediatric, adolescent, and young adult cancer survivors: A systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/critrevonc
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2011292952
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33675909&amp;id=doi:10.1016%2Fj.critrevonc.2021.103291&amp;issn=1040-8428&amp;isbn=&amp;volume=160&amp;issue=&amp;spage=103291&amp;pages=&amp;date=2021&amp;title=Critical+Reviews+in+Oncology%2FHematology&amp;atitle=Psychosocial%2C+behavioral%2C+and+supportive+interventions+for+pediatric%2C+adolescent%2C+and+young+adult+cancer+survivors%3A+A+systematic+review+and+meta-analysis&amp;aulast=Zhang&amp;pid=%3Cauthor%3EZhang+A.%3C%2Fauthor%3E%3CAN%3E2011292952%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 160 (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Both chronic and acute exercise interventions have reported positive effects on executive functions (EFs) in general populations. However, data on changes in EFs in children and adolescents with autism spectrum disorder (ASD) in response to exercise interventions are still unclear. 

**OBJECTIVE: **
This systematic review and meta-analysis aimed to synthesize available empirical studies concerning the effects of exercise interventions on EFs in children and adolescents with ASD. 

**METHODS:** 
In accordance with the Preferred Reporting Items for Systematic Review and Meta-analyses guidelines, the electronic databases CINAHL Complete (via EBSCOhost), SPORTDiscus with Full Text (via EBSCOhost), MEDLINE (via EBSCOhost), Web of Science, ProQuest, and Education Resources Information Center (ERIC; via EBSCOhost) were searched from inception to January 2021. Two authors independently extracted data and conducted a risk-of-bias analysis using the Physiotherapy Evidence Database scale. Randomized controlled trials/quasi-experimental designs that used acute or chronic exercise interventions and assessed EFs through neurocognitive tasks or questionnaires among children and adolescents with ASD were included. In total, 259 articles were identified, of which 15 full texts were independently assessed for eligibility by two authors. In total, 14 articles underwent systematic review, and seven were selected for meta-analysis. 

**RESULTS: **
Overall, chronic exercise interventions had a small to moderate positive effect on overall EFs in children and adolescents with ASD (g = 0.342; 95% confidence interval [CI] 0.084-0.600; p &lt; 0.01). Regarding domain-specific EFs, chronic exercise interventions had a small to moderate positive effect on cognitive flexibility (g = 0.312; 95% CI 0.053-0.570; p &lt; 0.01) and inhibitory control (g = 0.492; 95% CI 0.188-0.796; p &lt; 0.01). However, our review found a non-significant effect size (g = 0.212; 95% CI - 0.088 to 0.512) on working memory. 

**CONCLUSIONS: **
Chronic exercise interventions appear to have beneficial effects on overall EFs in children and adolescents with ASD, particularly in relation to cognitive flexibility and inhibitory control.
AN  - 34468951
AU  - Liang,
AU  - X.
AU  - Li,
AU  - R.
AU  - Wong,
AU  - S.
AU  - H.
AU  - S.
AU  - Sum,
AU  - R.
AU  - K.
AU  - W.
AU  - Wang,
AU  - P.
AU  - Yang,
AU  - B.
AU  - Sit,
AU  - C.
AU  - H.
AU  - P.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s40279-021-01545-3
L1  - internal-pdf://2287544415/Liang-2021-The Effects of Exercise Interventio.pdf
PY  - 2021
SP  - 01
T2  - Sports Medicine
TI  - The Effects of Exercise Interventions on Executive Functions in Children and Adolescents with Autism Spectrum Disorder: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34468951
UR  - https://link.springer.com/content/pdf/10.1007/s40279-021-01545-3.pdf
VL  - 01
ER  -
TY  - JOUR
AB  - Development of innovative and time-efficient strategies to involve youth in physical activity is pivotal in the actual inactivity pandemic. Moreover, physical activity may improve academic performance, of great interest for educators. 

This present systematic review aimed to analyze the effects of high-intensity interval training (HIIT) on cognitive performance and psychological outcomes in youth. A database search (Web of Science, PubMed, Scopus, and PsycINFO) for original research articles was performed. A total of eight articles met the inclusion criteria, and the Cochrane risk of bias tool was used. The studies&#039; results were recalculated to determine effect sizes using Cohen&#039;s d. Different HIIT interventions reported improvements on cognitive performance at executive function (d = 0.75, +78.56%), linguistic reasoning (d = 0.25, +7.66%), concentration (d = 0.71, +61.10%), selective attention (d = 0.81, +60.73%), non-verbal and verbal abilities (d = 0.88, +47.50%; d = 1.58, +22.61%, respectively), abstract reasoning (d = 0.75, +44.50%), spatial and numerical abilities (d = 37.19, +22.85%; d = 1.20, +8.28%, respectively), and verbal reasoning (d = 1.00, +15.71%) in youth. Regarding psychological outcomes, HIIT showed higher self-concept (d = 0.28, +8.71%) and psychological well-being in boys and girls (d = 0.73, +32.43%, d = 0.39, +11.58%, respectively). 

To sum up, HIIT interventions between 4-16 weeks, for 8-30 min/session, at &gt;=85% maximal heart rate, would provide positive effects on cognitive performance and psychological outcomes in youth.
AN  - 34067861
AU  - Alves,
AU  - A.
AU  - R.
AU  - Dias,
AU  - R.
AU  - Neiva,
AU  - H.
AU  - P.
AU  - Marinho,
AU  - D.
AU  - A.
AU  - Marques,
AU  - M.
AU  - C.
AU  - Sousa,
AU  - A.
AU  - C.
AU  - Loureiro,
AU  - V.
AU  - Loureiro,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph18105344
L1  - internal-pdf://3350940161/Alves-2021-High-Intensity Interval Training up.pdf
PY  - 2021
SP  - 17
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - High-Intensity Interval Training upon Cognitive and Psychological Outcomes in Youth: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med18&amp;AN=34067861
UR  - https://res.mdpi.com/d_attachment/ijerph/ijerph-14-00156/article_deploy/ijerph-14-00156.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - Attention Bias Modification (ABM) is a novel computerized therapy for anxiety disorders and is thought to augment the effect of Cognitive Behavior Therapy (CBT) as it may target different mechanisms. Recently, a growing number of studies have examined the combined effects of ABM and CBT on clinically anxious patients, with mixed results. This review examined the combined efficacy of ABM and CBT. A literature search was conducted in four main databases: PsycINFO, Embase, Pubmed and the Cochrane library, resulting in 11 randomized studies. The combination of ABM and CBT had small but significant effects on clinician-rated anxiety symptoms and attention bias towards threat compared to the control group, while ESs for anxiety (all measures), self-reported or parent-reported anxiety measures and depression symptoms were non-significant. Studies in which ABM was conducted as an integral part of each CBT session yielded greater reduction in anxiety symptoms than those conducting ABM and CBT at separate time points. Older participants and patients with social anxiety disorder tended to benefit less from the combination of ABM and CBT based on bias scores. This study may provide preliminary evidence that ABM and CBT have the potential to complement each other, especially when they are conducted integrally.
AN  - WOS:000641345000033
AU  - Hang,
AU  - Y.
AU  - M.
AU  - Xu,
AU  - L.
AU  - Wang,
AU  - C.
AU  - Zhang,
AU  - G.
AU  - J.
AU  - Zhang,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.psychres.2021.113892
L1  - internal-pdf://1137943326/Hang-2021-Can attention bias modification augm.pdf
PY  - 2021
SP  - 9
T2  - Psychiatry Research
TI  - Can attention bias modification augment the effect of CBT for anxiety disorders? A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000641345000033
VL  - 299
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Parent-Child Interaction Therapy (PCIT) is a well-established treatment for behavioural, hyperactivity and oppositional-defiant problems in children. Previous meta-analyses are scarce, and they have tended to mix problems and measures. 

**OBJECTIVE**
A meta-analysis study was conducted with all available studies on PCIT (1980 to 2020) to determine its specific efficacy and effectiveness for child behavioural problems. METHOD: Selection from databases collected a total of 100 studies. The inclusion criteria were to compare PCIT in children with behavioural problems between 2 and 12 years of age; comparing groups and using standardized instruments. 

**RESULTS**
PCIT exhibited a significant mean effect size ( d = -0.87 [95% CI: -1.10, -0.63] versus control and/or treatment-as-usual groups, but the effect size was smaller and not significant in follow-ups ( d = -0.23 [95% CI: -0.49, 0.04]). The within-group studies, comparing versions of PCIT, also demonstrated a significant effect size ( d = -0.26 (95% CI: -0.43, -0.08), and in pre-post comparisons this effect was greater ( d = -1.40 [95% CI: -1.69, -1.10]). CONCLUSIONS: PCIT is an effective intervention for treating child behaviour problems such as disruptive, hyperactive, negative, and externalizing problems. It is supported by 40 years of experimental and clinical studies, and also by this meta-analysis.
AN  - 34668468
AU  - Valero-Aguayo,
AU  - L.
AU  - Rodriguez-Bocanegra,
AU  - M.
AU  - Ferro-Garcia,
AU  - R.
AU  - Ascanio-Velasco,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.7334/psicothema2021.70
L1  - internal-pdf://0819901687/Valero-Aguayo-2021-Meta-analysis of the Effica.pdf
PY  - 2021
SP  - 544-555
T2  - Psicothema
TI  - Meta-analysis of the Efficacy and Effectiveness of Parent Child Interaction Therapy (PCIT) for Child Behaviour Problems
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34668468
VL  - 33
ER  -
TY  - JOUR
AB  - OBJECTIVES: This systematic review aims to examine the effectiveness of online mental health interventions for youth. 

METHODS: We searched seven electronic databases (PubMed, PsycINFO, Medline, Embase, CINAHL, Web of Science and SCOPUS) for the past 10 years to identify randomized controlled trials which have evaluated the use of telehealth interventions for young people with mental health problems. The included studies were assessed for quality and risk of bias.

RESULTS: Forty-five randomized controlled trials (n = 13,291 participants) were eligible for this review. Most studies (35 trials) evaluated the use of web-based self-help platforms to deliver cognitive behavioural therapy (14 trials), mindfulness (four trials), acceptance commitment therapy (five trials) and positive psychology (two trials). Mobile/computer applications were used to deliver cognitive behavioural therapy (four trials) and coping strategies training (two trials). Web-based synchronous chat (one trial) was used to assist communication between counsellors and participants. Three studies used artificial intelligence-based conversational agents to deliver cognitive behavioural therapy (two trials) and problem-solving-strategy training (one trial). Eighty-two percent (n = 37) identified the participants as student population (i.e. university students, high school students). Sixty-four percent (n = 29) of the telehealth interventions were found to be effective in managing depression, anxiety, stress, insomnia and improving quality of life when compared with control conditions. 

CONCLUSIONS: Online mental health interventions were found to be effective in managing diverse mental health conditions among youth. Online self-help platforms were the most frequently used modality and artificial intelligence-based chatbots are merging as potential solutions. Future research is warranted to investigate the solutions to improve the retention rate and satisfaction of telehealth interventions among this population.
AN  - 34726992
AU  - Zhou,
AU  - X.
AU  - Edirippulige,
AU  - S.
AU  - Bai,
AU  - X.
AU  - Bambling,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1357633X211047285
L1  - internal-pdf://0009425080/Are online mental health interventions fo-2021.pdf
PY  - 2021
SP  - 638-666
T2  - Journal of Telemedicine &amp; Telecare
TI  - Are online mental health interventions for youth effective? A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34726992
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1357633X211047285
VL  - 27
ER  -
TY  - JOUR
AB  - Children and adolescents with ASD also have co-occurrence of attention deficit hyperactivity disorder (ADHD) symptoms. ADHD symptoms, especially hyperactivity, greatly increased the severity of autism symptoms. This study concentrated on two widely-used medications: the second generation of antipsychotics (SGAs) and ADHD medication, aiming to conduct a meta-analysis about their effect on hyperactivity, so it would offer some evidence for clinical medication choice. The Medline, Embase, Cochrane Central Register of Controlled Trials and China National Knowledge Infrastructure databases were searched from inception to July 2019 for studies exploring the use of SGAs and ADHD medications in autistic children and adolescents. Double-blind, randomized controlled trials that reported hyperactivity as an outcome were included in the study. A total of thirteen trials with 712 participants were included in our meta-analysis. For SGAs, the standardized mean difference (SMD) of hyperactivity subscale in Aberrant behavior checklist scale or conners rating scales was 0.59, 95% confidence interval (CI): 0.23-0.96, I2 = 74%, Q = 15.34, P &lt; 0.01. For ADHD medications, SMD was -0.66, with 95% CI: -0.99 to 0.33, I2 = 53%, Q = 15.02, P = 0.04. As for adverse events, in the SGAs group, somnolence had the largest effect size, risk ratio = 5.62, 95% CI: 3.20- 9.87 (I2 = 0%, Q = 2.45, P = 0.65). In ADHD group, the side effect of decreased appetite showed the largest effect size (risk ratio = 2.63, 95% CI = 0.99-7.01, I2 = 65.7%, Q = 11.66, P = 0.02). Both ADHD medications and SGAs were effective in dealing with hyperactivity in children and adolescents with autism but were shown to increase the risk of decreased appetite, somnolence, headache and nausea or vomiting. The clinical use of these medications should carefully weigh the benefits and risks.
AN  - WOS:000639294500001
AU  - Wang,
AU  - F.
AU  - Wen,
AU  - F.
AU  - Yu,
AU  - L.
AU  - P.
AU  - Yan,
AU  - J.
AU  - J.
AU  - Liu,
AU  - J.
AU  - R.
AU  - Li,
AU  - Y.
AU  - Cui,
AU  - Y.
AU  - H.
DA  - MAY
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/YIC.0000000000000349
L1  - internal-pdf://1806200082/Wang-2021-The efficacy and safety in attention.pdf
PY  - 2021
SP  - 109-116
T2  - INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY
TI  - The efficacy and safety in attention deficit hyperactivity disorder of second-generation antipsychotics and other medications for hyperactivity in children and adolescents with autism: a meta-analysis
VL  - 36
ER  -
TY  - JOUR
AB  - Meta-analyses have shown that digital mental health apps can be efficacious in reducing symptoms of depression and anxiety. However, real-world usage of apps is typically not sustained over time, and no studies systematically examine which features increase sustained engagement with apps or the relationship between engagement features and clinical efficacy. 

We conducted a systematic search of the literature to identify empirical studies that (1) investigate standalone apps for depression and/or anxiety in symptomatic participants and (2) report at least one measure of engagement. Features intended to increase engagement were categorized using the persuasive system design (PSD) framework and principles of behavioral economics. 

Twenty-five studies with 4159 participants were included in the analysis. PSD features were commonly used, whereas behavioral economics techniques were not. Smartphone apps were efficacious in treating symptoms of anxiety and depression in randomized controlled trials, with overall small-to-medium effects (g = 0.2888, SE = 0.0999, z(15) = 2.89, p = 0.0119, Q(df = 14) = 41.93, p &lt; 0.0001, I&lt;sup&gt;2&lt;/sup&gt; = 66.6%), and apps that employed a greater number of engagement features as compared to the control condition had larger effect sizes (beta = 0.0450, SE = 0.0164, t(15) = 2.7344, p = 0.0161). We observed an unexpected negative association between PSD features and engagement, as measured by completion rate (beta = -0.0293, SE = 0.0121, t(17) = 02.4142, p = 0.0281). Overall, PSD features show promise for augmenting app efficacy, though engagement, as reflected in study completion, may not be the primary factor driving this association. 

The results suggest that expanding the use of PSD features in mental health apps may increase clinical benefits and that other techniques, such as those informed by behavioral economics, are employed infrequently. Copyright &copy; 2021, The Author(s).
AN  - 2010468517
AU  - Wu,
AU  - A.
AU  - Scult,
AU  - M.
AU  - A.
AU  - Barnes,
AU  - E.
AU  - D.
AU  - Betancourt,
AU  - J.
AU  - A.
AU  - Falk,
AU  - A.
AU  - Gunning,
AU  - F.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1038/s41746-021-00386-8
L1  - internal-pdf://0264369227/Wu-2021-Smartphone apps for depression and anx.pdf
PY  - 2021
T2  - npj Digital Medicine
TI  - Smartphone apps for depression and anxiety: a systematic review and meta-analysis of techniques to increase engagement
UR  - https://www.nature.com/npjdigitalmed/
UR  - https://www.nature.com/articles/s41746-021-00386-8.pdf
VL  - 4 (1) (no pagination)
ER  -
TY  - JOUR
AB  - **Background**
In‐hospital growth of preterm infants remains a challenge in clinical practice. The high nutrient demands of preterm infants often lead to growth faltering. For preterm infants who cannot be fed maternal or donor breast milk or may require supplementation, preterm formulas with fat in the form of medium chain triglycerides (MCTs) or long chain triglycerides (LCTs) may be chosen to support nutrient utilization and to improve growth. MCTs are easily accessible to the preterm infant with an immature digestive system, and LCTs are beneficial for central nervous system development and visual function. Both have been incorporated into preterm formulas in varying amounts, but their effects on the preterm infant&#039;s short‐term growth remain unclear. This is an update of a review originally published in 2002, then in 2007.

**Objectives**
To determine the effects of formula containing high as opposed to low MCTs on early growth in preterm infants fed a diet consisting primarily of formula. 

**Search methods**
We used the standard search strategy of Cochrane Neonatal to search Cochrane Central Register of Controlled Trials (CENTRAL; 2020, Issue 8), in the Cochrane Library; Ovid MEDLINE Epub Ahead of Print, In‐Process &amp; Other Non‐Indexed Citations, Ovid MEDLINE(R) Daily, and Ovid MEDLINE(R); MEDLINE via PubMed for the previous year; and Cumulative Index to Nursing and Allied Health Literature (CINAHL), on 16 September 2020. We also searched clinical trials databases and the reference lists of retrieved articles for randomized controlled trials (RCTs) and quasi‐RCTs.Selection criteriaWe included all randomized and quasi‐randomized trials comparing the effects of feeding high versus low MCT formula (for a minimum of five days) on the short‐term growth of preterm (&lt; 37 weeks&#039; gestation) infants. We defined high MCT formula as 30% or more by weight, and low MCT formula as less than 30% by weight. The infants must be on full enteral diets, and the allocated formula must be the predominant source of nutrition.

**Data collection and analysis**
The review authors assessed each study&#039;s quality and extracted data on growth parameters as well as adverse effects from included studies. All data used in analysis were continuous; therefore, mean differences with 95% confidence intervals were reported. We used the GRADE approach to assess the certainty of evidence.

**Main results**
We identified 10 eligible trials (253 infants) and extracted relevant growth data from 7 of these trials (136 infants). These studies were found to provide evidence of very low to low certainty. Risk of bias was noted, as few studies described specific methods for random sequence generation, allocation concealment, or blinding. We found no evidence of differences in short‐term growth parameters when high and low MCT formulas were compared.

As compared to low MCT formula, preterm infants fed high MCT formula showed little to no difference in weight gain velocity (g/kg/d) during the intervention, with a typical mean difference (MD) of ‐0.21 g/kg/d (95% confidence interval (CI) ‐1.24 to 0.83; 6 studies, 118 infants; low‐certainty evidence). The analysis for weight gain (g/d) did not show evidence of differences, with an MD of 0.00 g/d (95% CI ‐5.93 to 5.93; 1 study, 18 infants; very low‐certainty evidence), finding an average weight gain of 20 &plusmn; 5.9 versus 20 &plusmn; 6.9 g/d for high and low MCT groups, respectively. We found that length gain showed no difference between low and high MCT formulas, with a typical MD of 0.10 cm/week (95% CI ‐0.09 to 0.29; 3 studies, 61 infants; very low‐certainty evidence). Head circumference gain also showed little to no difference during the intervention period, with an MD of ‐0.04 cm/week (95% CI ‐0.17 to 0.09; 3 studies, 61 infants; low‐certainty evidence). Two studies reported skinfold thickness with different measurement definitions, and evidence was insufficient to determine if there was a difference (2 studies, 32 infants; very low‐certainty evidence). There are conflicting data (5 studies) as to formula tolerance, with 4 studies reporting narrative results of no observed clinical difference and 1 study reporting higher incidence of signs of gastrointestinal intolerance in high MCT formula groups. There is no evidence of effect on the incidence of necrotizing enterocolitis (NEC), based on small numbers in two trials. Review authors found no studies addressing long‐term growth parameters or neurodevelopmental outcomes.

**Authors&#039; conclusions**
We found evidence of very low to low certainty suggesting no differences among short‐term growth data for infants fed low versus high MCT formulas. Due to lack of evidence and uncertainty, neither formula type could be concluded to improve short‐term growth outcomes or have fewer adverse effects. Further studies are necessary because the results from included studies are imprecise due to small numbers and do not address important long‐term outcomes. Additional research should aim to clarify effects on formula tolerance and on long‐term growth and neurodevelopmental outcomes, and should include larger study populations to better evaluate effect on NEC incidence.
AU  - Perretta,
AU  - L.
AU  - Ouldibbat,
AU  - L.
AU  - Hagadorn,
AU  - J.
AU  - I.
AU  - Brumberg,
AU  - H.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD002777.pub2
L1  - internal-pdf://0461495937/Perretta_et_al-2021-Cochrane_Database_of_Syste.pdf
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - High versus low medium chain triglyceride content of formula for promoting short-term growth of preterm infants
ER  -
TY  - JOUR
AB  - **Background:**
Home visiting programs are widely endorsed for preventing child maltreatment. Yet, knowledge is lacking on what and how individual program components are related to the effectiveness of these programs. 

**Objective(s):** 
The aim of this meta-analysis was to increase this knowledge by summarizing findings on effects of home visiting programs on child maltreatment and by examining potential moderators of this effect, including a range of program components and delivery techniques. 

**Method(s):** 
A literature search yielded 77 studies (N=48,761) examining the effectiveness of home visiting programs, producing 174 effect sizes. In total, 35 different program components and delivery techniques were coded. 

**Result(s):** 
A small but significant overall effect was found (d=0.135, 95 % CI (0.084, 0.187), p&lt;0.001). Programs that focused on improving parental expectations of the child or parenthood in general (d = 0.308 for programs with this component versus d = 0.112 for programs without this component), programs targeting parental responsiveness or sensitivity to a child&#039;s needs (d = 0.238 versus d = 0.064), and programs using video-based feedback (d = 0.397 versus d = 0.124) yielded relatively larger effects. Providing practical and instrumental assistance was negatively associated with program effectiveness (d=0.044 versus d = 0.168). Further, program effects were larger when percentages of non-Caucasians/non-Whites in samples and follow-up durations increased. 

**Conclusion(s):** 
In general, home visiting programs can prevent child maltreatment only to a small extent. However, implementing specific components and techniques can improve program effectiveness. Copyright &copy; 2021 The Author(s)
AD  - (Gubbels, van der Put, Stams, Assink) Research Institute of Child Development and Education, University of Amsterdam, Nieuwe Achtergracht 127, Amsterdam 1018 WS, Netherlands (Prinzie) Erasmus University Rotterdam, Erasmus School of Social and Behavioral Sciences, Department of Psychology, Education &amp; Child Studies, Burgemeester Oudlaan 50, Rotterdam 3062 PA, NetherlandsJ. Gubbels, Research Institute of Child Development and Education, University of Amsterdam, P.O. Box 15780, Amsterdam 1001 NG, Netherlands. E-mail: J.Gubbels@uva.nl
AU  - Gubbels,
AU  - J.
AU  - van
AU  - der
AU  - Put,
AU  - C.
AU  - E.
AU  - Stams,
AU  - G.
AU  - J.
AU  - J.
AU  - M.
AU  - Prinzie,
AU  - P.
AU  - J.
AU  - Assink,
AU  - M.
DA  - April
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.chiabu.2021.104981
DP  - Ovid Technologies
KW  - Child abuse
KW  - Child maltreatment
KW  - Home visitation
KW  - Home visiting
KW  - Meta-analysis
KW  - Program components
KW  - article
KW  - child
KW  - effect size
KW  - expectation
KW  - female
KW  - follow up
KW  - human
KW  - male
KW  - meta analysis
KW  - parenthood
KW  - program effectiveness
KW  - systematic review
KW  - videorecording
L1  - internal-pdf://3304370734/Gubbels-2021.pdf
LA  - English
PY  - 2021
T2  - Child Abuse and Neglect
TI  - Components associated with the effect of home visiting programs on child maltreatment: A meta-analytic review
UR  - http://www.elsevier.com/locate/chiabuneg
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010943608
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33571741&amp;id=doi:10.1016%2Fj.chiabu.2021.104981&amp;issn=0145-2134&amp;isbn=&amp;volume=114&amp;issue=&amp;spage=104981&amp;pages=&amp;date=2021&amp;title=Child+Abuse+and+Neglect&amp;atitle=Components+associated+with+the+effect+of+home+visiting+programs+on+child+maltreatment%3A+A+meta-analytic+review&amp;aulast=Gubbels&amp;pid=%3Cauthor%3EGubbels+J.%3C%2Fauthor%3E%3CAN%3E2010943608%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
VL  - 114 (no pagination)
ER  -
TY  - JOUR
AB  - AIM: Cognitive deficits are recognized features of depressive disorders in youth aged 12-25. These deficits are distressing, predict functional impairment and limit the effectiveness of psychological therapies. Cognitive enhancement using behavioural, biochemical or physical treatments may be useful in young people with depression, but studies have not been synthesized. The aim was to systematically review the evidence for treatments for objective and subjective cognitive functioning, and their acceptability and functional outcomes in people aged 12-25 with depression. 

METHOD: Three electronic databases were searched for articles using pre-specified criteria. Pharmacological treatments were not eligible. Risk of bias was rated using the Cochrane Collaboration&#039;s revised risk-of-bias tool. Dual full-text article screening, data extraction and quality ratings were completed. 

RESULTS: Twelve studies were included for review (median participant age: 20.39 years), five of which were randomized-controlled trials (RCTs). Sample sizes were generally small (median = 23; range: 9-46). Eight studies investigated behavioural treatments including aerobic exercise, cognitive training and education or strategy-based methods. Four studies examined repetitive transcranial magnetic brain stimulation (rTMS). Most behavioural treatments revealed preliminary evidence of improved cognitive function in youth depression. Consent rates were greatest for exercise- and education-based approaches, which may indicate higher acceptability levels. Findings from rTMS trials were mixed, with only half showing cognitive improvement. Functional outcomes were reported by three behavioural treatment trials and one rTMS trial, with functional improvement reported only in the former. Some concern of risk of bias was found in each RCT. 

CONCLUSION: Behavioural treatments, such as exercise, cognitive training and education/strategy-focused techniques, show encouraging results and appear to be acceptable methods of addressing cognitive deficits in youth depression based on participation rates. Brain stimulation and biochemical treatments (e.g., nutrient-based treatment) require further investigation.
AN  - 34825492
AU  - Daglas-Georgiou,
AU  - R.
AU  - Bryce,
AU  - S.
AU  - Smith,
AU  - G.
AU  - Kaur,
AU  - M.
AU  - Cheng,
AU  - N.
AU  - De
AU  - Rozario,
AU  - M.
AU  - Wood,
AU  - S.
AU  - J.
AU  - Allott,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/eip.13248
L1  - internal-pdf://0847946966/Daglas-Georgiou-2021.pdf
PY  - 2021
SP  - 25
T2  - Early intervention in psychiatry
TI  - Treatments for objective and subjective cognitive functioning in young people with depression: Systematic review of current evidence
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34825492
UR  - https://onlinelibrary.wiley.com/doi/10.1111/eip.13248
VL  - 25
ER  -
TY  - JOUR
AB  - Exposure to trauma at a younger age has been associated with an increased likelihood of developing PTSD. School-based interventions have been utilized to address traumatic stress and PTSD symptoms in children. However, to date, no meta-analyses have been performed to evaluate the strength of intervention impacts on PTS symptoms in school-aged children, ages 5-11. 

Thus, the current review sought to address these gaps. Nine international databases were searched during the study&#039;s timeframe. Inclusion criteria were: (1) randomized controlled trials of an intervention or prevention program, (2) implementation in a school-based setting, (3) children aged 5-11, and (4) an outcome variable for PTS or PTSD. Although 26 studies met the above criteria, 21 studies met all inclusion criteria, including the data necessary to run the analysis, and were ultimately included in the meta-analysis. Random effects models were used; the standard mean difference was reported at -.30, which was determined as statistically significant (t = - 2.70, p = .01; 95% CI: [- 0.52, -0.07]). 

The results indicate that school-based interventions can effectively reduce posttraumatic stress in young children. These results indicate that school-based programs to address trauma in children may be an effective strategy to reduce PTS-related symptoms. Some limitations include a small number of studies included in the meta-analysis. Additionally, few studies reported enough detail to determine racial and ethnic demographic and specific age outcomes. 

As a result, it was not possible to isolate the specific effects on the intended age group and conduct moderator effects for racial and ethnic demographic data.
AN  - WOS:000673881100001
AU  - Bagneris,
AU  - J.
AU  - R.
AU  - Noel,
AU  - L.
AU  - Harris,
AU  - R.
AU  - Bennett,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12310-021-09451-9
L1  - internal-pdf://0036589127/Bagneris-School-Based Interventions for Posttr.pdf
PY  - 2021
SP  - 13
T2  - School Mental Health
TI  - School-Based Interventions for Posttraumatic Stress Among Children (Ages 5-11): Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000673881100001
UR  - https://link.springer.com/content/pdf/10.1007/s12310-021-09451-9.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: There are not many drugs for teen depression, and many antidepressants are not recommended for people under the age of 14 years. Thus, cognitive behavioral therapy, such as art therapy, is widely used in the treatment of adolescent depression. Group painting therapy (GPT) is a psycho-art treatment that allows the artist to engage in the creative process of painting. 

METHODS: Chinese and English databases were searched with a combination of words, including &quot;Adolescent depression&quot;, &quot;Group painting therapy&quot;, &quot;Art therapy&quot;, and &quot;Depression&quot;. A meta-analysis of the literature was carried out using the Cochrane system (RevMan 5.3). 

RESULTS: Six randomized controlled trials (RCTs) were included in this study, of which 4 (66.66%) adopted the correct random assignment method, and 1 (16.67%) adopted a hidden detailed assignment scheme. One (16.67%) article adopted a blind method to evaluate the results. After GPT, depressed adolescent patients&#039; positive emotion scores improved significantly [mean deviation (MD) =4.62, 95% confidence interval (CI) (3.79, 5.45), P&lt;0.01] as did patients&#039; negative emotion scores [MD =-1.88, 95% CI (-2.29, -1.46), P&lt;0.01]. Patients&#039; cognitive function and executive ability were also significantly improved by GPT. 

DISCUSSION: The results of our systematic evaluation and meta-analysis confirmed that GPT significantly improves adolescent depression and relieves patients&#039; negative emotions.
AN  - 34763436
AU  - Yuan,
AU  - Z.
AU  - Li,
AU  - B.
AU  - Ye,
AU  - X.
AU  - Zhu,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.21037/apm-21-2474
L1  - internal-pdf://0633916702/Systematic review and meta-analysis of th-2021.pdf
PY  - 2021
SP  - 10744-10755
T2  - Annals of Palliative Medicine
TI  - Systematic review and meta-analysis of the effects of group painting therapy on the negative emotions of depressed adolescent patients
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34763436
UR  - https://apm.amegroups.com/article/viewFile/81400/pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **Objective**: The authors systematically reviewed evidence on pharmacotherapy for perinatal mental health disorders. Method(s): The authors searched for studies of pregnant, postpartum, or reproductive-age women with mental health disorders treated with pharmacotherapy in MEDLINE, EMBASE, PsycINFO, the Cochrane Library, and trial registries from database inception through June 5, 2020 and surveilled literature through March 2, 2021. Outcomes included symptoms; functional capacity; quality of life; suicidal events; death; and maternal, fetal, infant, or child adverse events. 

**Result(s)**: 164 studies were included. Regarding benefits, brexanolone for third-trimester or postpartum depression onset may be associated with improved depressive symptoms at 30 days when compared with placebo. Sertraline for postpartum depression may be associated with improved response, remission, and depressive symptoms when compared with placebo. Discontinuing mood stabilizers during pregnancy may be associated with increased recurrence of mood episodes for bipolar disorder. Regarding adverse events, most studies were observational and unable to fully account for confounding. Evidence on congenital and cardiac anomalies for treatment compared with no treatment was inconclusive. Brexanolone for depression onset in the third trimester or the postpartum period may be associated with risk of sedation or somnolence, leading to dose interruption or reduction when compared with placebo. 

**Conclusion(s)**: Evidence from few studies supports the use of pharmacotherapy for perinatal mental health disorders. Although many studies report on adverse events, they could not rule out underlying disease severity as the cause of the association between exposures and adverse events. Patients and clinicians need to make informed, collaborative decisions on treatment choices. Copyright &copy; 2021 The Authors. Psychiatric Research and Clinical Practice published by Wiley Periodicals LLC. on behalf of the American Psychiatric Association
AD  - (Viswanathan, Middleton, Berkman, Coker-Schwimmer, Baker, Voisin, Bann, Gaynes) RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center, Chapel Hill, United States (Viswanathan, Berkman, Bann) RTI International, Research Triangle Park, Chapel Hill, NC, United States (Middleton, McLaurin-Jiang, Dotson, Coker-Schwimmer, Baker, Voisin) Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, United States (Stuebe, Goulding) Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, United States (Stuebe) Department of Maternal and Child Health, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, United States (Gaynes) Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, United States (Gaynes) Department of Epidemiology Gillings Global School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, United StatesM. Viswanathan, RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center, Chapel Hill, United States. E-mail: viswanathan@rti.org
AN  - 2011402039
AU  - Viswanathan,
AU  - M.
AU  - Middleton,
AU  - J.
AU  - C.
AU  - Stuebe,
AU  - A.
AU  - M.
AU  - Berkman,
AU  - N.
AU  - D.
AU  - Goulding,
AU  - A.
AU  - N.
AU  - McLaurin-Jiang,
AU  - S.
AU  - Dotson,
AU  - A.
AU  - B.
AU  - Coker-Schwimmer,
AU  - M.
AU  - Baker,
AU  - C.
AU  - Voisin,
AU  - C.
AU  - E.
AU  - Bann,
AU  - C.
AU  - Gaynes,
AU  - B.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1176/appi.prcp.20210001
DP  - Ovid Technologies
KW  - adult
KW  - bipolar disorder
KW  - child
KW  - Cochrane Library
KW  - congenital heart malformation
KW  - drug therapy
KW  - Embase
KW  - female
KW  - fetus
KW  - functional status
KW  - human
KW  - infant
KW  - Medline
KW  - mental disease
KW  - meta analysis
KW  - mood
KW  - postnatal depression
KW  - PsycINFO
KW  - quality of life
KW  - remission
KW  - review
KW  - sedation
KW  - somnolence
KW  - systematic review
KW  - third trimester pregnancy
KW  - brexanolone
KW  - placebo
KW  - sertraline
L1  - internal-pdf://0728922954/Viswanathan-2021-Maternal, Fetal, and Child Ou.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDate of Publication: 2021
PY  - 2021
T2  - Psychiatric Research and Clinical Practice.
TI  - Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Meta-Analysis of Pharmacotherapy
UR  - https://onlinelibrary.wiley.com/journal/25755609
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2011402039
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1176%2Fappi.prcp.20210001&amp;issn=2575-5609&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Psychiatric+Research+and+Clinical+Practice&amp;atitle=Maternal%2C+Fetal%2C+and+Child+Outcomes+of+Mental+Health+Treatments+in+Women%3A+A+Meta-Analysis+of+Pharmacotherapy&amp;aulast=Viswanathan&amp;pid=%3Cauthor%3EViswanathan+M.%3C%2Fauthor%3E%3CAN%3E2011402039%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Background**
Depression and anxiety disorders are considered to be among the greatest burdens of disease in children and adolescents. Recent literature has reported music therapy to be a safe and potentially effective intervention for the treatment of depression and anxiety. This systematic review examined the effectiveness of music therapy in reducing the symptom severity of depression and/or anxiety among children and adolescents. 

**Methods**
Randomized controlled trials (RCTs) were obtained from a systematic search of nine major English databases from inception to January 2021. Studies were categorized by outcome, music therapy technique and follow-up period. 

**Results**
Seven RCTs (n = 589) were included. Four RCTs had some concern of bias, while three had high risk of bias. Statistical pooling was not appropriate due to clinical heterogeneity. Four studies (n = 428) favoured music therapy for improvement of depressive symptoms at short- and intermediate-term follow-ups compared to control. One study (n = 106) favoured music therapy for improvement of anxiety symptoms at short-term follow-up compared to control. No studies favoured any control over music therapy for symptom improvement of depression and/or anxiety. 

**Conclusion**
Limited evidence suggests music therapy is an effective treatment for improving depression and/or anxiety symptom severity in children and adolescents. More high-quality RCTs are needed to address methodological flaws of current studies.
AN  - WOS:000724456900001
AU  - Belski,
AU  - N.
AU  - Abdul-Rahman,
AU  - Z.
AU  - Youn,
AU  - E.
AU  - Balasundaram,
AU  - V.
AU  - Diep,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/camh.12526
L1  - internal-pdf://0507973246/Child Adoles Ment Health - 2021 - Belski - Rev.pdf
PY  - 2021
SP  - 9
T2  - Child and Adolescent Mental Health
TI  - Review: The effectiveness of musical therapy in improving depression and anxiety symptoms among children and adolescents - a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000724456900001
UR  - https://acamh.onlinelibrary.wiley.com/doi/10.1111/camh.12526
ER  -
TY  - JOUR
AB  - **Background** Rates of physical activity decline throughout adolescence, and evidence indicates that this has an adverse impact on psychological health. This paper aims to synthesise available evidence for physical activity interventions on the mental health and well-being of young people (11-19 years) from the general population. 

**Method** Nine databases were searched to identify studies published between January 2005 and June 2020: Web of Science, ProQuest Psychology Journals, PsycINFO, Pub Med, ASSIA, CINHAL PLUS, SPORTDiscus, EMBASE and Wiley Online Library. Key search terms included &#039;physical activity intervention&#039;, &#039;mental health&#039; and &#039;adolescen*&#039;. Eligible studies were independently screened by two authors based on inclusion/exclusion criteria. 

**Results** Twenty-eight interventions were narratively synthesised in four categories: Quality of Life (QOL), self-esteem, psychological well-being and psychological ill-being (e.g. depression, stress). A large proportion (67.9%) of interventions were multicomponent and combined physical activity with other features such as health education (e.g. nutrition). However, only a limited number (N = 5) specifically addressed mental health. Findings suggest that interventions are useful in improving psychological well-being and QOL, yet evidence for self-esteem is mixed. 

**Conclusions** Although effectiveness in improving well-being is evident, evidence for a reduction in the frequency and severity of mental health problems is less clear. A summary of the overall impact of physical activity interventions on the mental health of young people is presented.
AN  - WOS:000659034400001
AU  - Hale,
AU  - G.
AU  - E.
AU  - Colquhoun,
AU  - L.
AU  - Lancastle,
AU  - D.
AU  - Lewis,
AU  - N.
AU  - Tyson,
AU  - P.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/camh.12485
L1  - internal-pdf://1877319743/Hale-Review_ Physical activity interventions f.pdf
PY  - 2021
SP  - 12
T2  - Child and Adolescent Mental Health
TI  - Review: Physical activity interventions for the mental health and well-being of adolescents - a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000659034400001
UR  - https://acamh.onlinelibrary.wiley.com/doi/10.1111/camh.12485
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/camh.12485?download=true
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Co-occurring mental health and substance use (SU) disorders among adolescents are common, with two-thirds of adolescents who seek SU treatment also requiring support for mental health. Primary care physicians play a key role in the pharmacological treatment of mental health disorders among adolescents, however, little is known about the impact of these treatments on SU outcomes. 

**OBJECTIVES: **
This systematic review summarizes the evidence regarding commonly used pharmacotherapy interventions for mental health and their impact on adolescent SU. 

**METHODS: **
Literature searches were conducted across five databases as part of a larger systematic review of adolescent SU interventions. Studies were screened for eligibility by two researchers, and study data were extracted regarding study design, patient and treatment characteristics and results. Risk of bias analyses and qualitative syntheses were completed to evaluate the strength of the evidence and the impact of pharmacotherapy on SU outcomes. 

**RESULTS: **
Ten randomized controlled trials exploring seven pharmacotherapies met criteria for inclusion. All studies had low to moderate risk of bias. Four studies evaluated pharmacotherapy for co-occurring depression and SU, three evaluated attention deficit hyperactivity disorder and SU, and three evaluated bipolar disorder and SU. Five of the 10 studies also included a behavioural intervention. We found no evidence that pharmacotherapy for co-occurring mental health diagnoses impacted SU. 

**CONCLUSION: **
Family medicine clinicians prescribing pharmacotherapy for mental health should be aware that additional interventions will likely be needed to address co-occurring SU.
AN  - 34448853
AU  - Scott,
AU  - K.
AU  - Becker,
AU  - S.
AU  - J.
AU  - Helseth,
AU  - S.
AU  - A.
AU  - Saldanha,
AU  - I.
AU  - J.
AU  - Balk,
AU  - E.
AU  - M.
AU  - Adam,
AU  - G.
AU  - P.
AU  - Konnyu,
AU  - K.
AU  - J.
AU  - Steele,
AU  - D.
AU  - W.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1093/fampra/cmab096
L1  - internal-pdf://1371224203/Scott-2021-Pharmacotherapy interventions for a.pdf
PY  - 2021
SP  - 27
T2  - Family Practice
TI  - Pharmacotherapy interventions for adolescent co-occurring substance use and mental health disorders: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34448853
UR  - https://academic.oup.com/fampra/advance-article-abstract/doi/10.1093/fampra/cmab096/6358606?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/cmab096.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAvQwggLwBgkqhkiG9w0BBwagggLhMIIC3QIBADCCAtYGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMf5CMG36_03hSx0C7AgEQgIICp7AP-Q6wbskwHk_2MEYGsqnYhTzi9neT_fzrEkaStt4TEOIQLJJSYEEY6HNQStDPWFcrNXqCUc33x5qKAPUW98TJjt8BVrOsuONsprsIJTHRfflsjX5FE1gW0ketVN90rQwgvZBUPdjm6d9sIRi5xcWNj9uviit4UcVUHpSzAjm1NA5OHGfIsPm6vVKwyycTy31PWAZY_HCedZ5mWOOoiYBt_AzNqZ1zjMMSyJtGGGQOgeFwMPMAyCG1wTd0fVijOIPaUlwH4I7Y_1C0Bqajf6ryEMV_FwARvCbp3WsxcDr4qfPKCAsKiI5nzpdtFeSiGOJm3EIEw2ZXI-PXCm5E-72eKB5_Nq5VUjS1MZfIKAjwfNTHy81wWOcQN94pMy-9ErN1ISqxKN9BVxtxyPcBrwkhKtyGj557hM4lh4dEHfZF2VswlfxZy3yjbgDl2jXKNwfD-yEfLCzLi0YF5_e3HyXpkCg-_G99DmcnH8d4FAnCVepl_1uTrs_6nPJIOEEqhRs5IPYETWeYXnInKERHptFZqFUwOlIB_OsQhlhyla21GMH9A0edst8-NtRYX2kAHxAgv4f43S6PyWxtaBTDXApWKZ0emV559u11o8O7CoL6mvAbiSzOGQqlxbe-DhV9s-cH0Cd9HKErHI1X15QqWXPInyD5f5B7aVc0bp_yU_OF347uqOuUK-iRQ7wfM4jGNTuobbIsKuZLVnyTK92fVBvK7U_d2YffkryTgg7UNTTZnyIQ-z38Cqb2-cMVBA4I_sFxYIXfwHLcQ-ciO-743gdZzOED7NtT8ZaPSHwY2wZWYuFtIIC9iBN_qbOspnbTrTZ8sdx1IPW0HT2w7xztcmMwtPa_vOkhvGE4XpJlYr7yBN6nwyhIW7hd2h4ztU5vkwOR1KUVT7Q
VL  - 27
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Cancer can have various psychosocial effects on children and young adults. Technology-based psychosocial interventions are increasingly popular in paediatric oncology for psychosocial health. 

**OBJECTIVE**
The objective of this study is to investigate the effectiveness of technology-based psychosocial interventions applied to children, adolescent and young adults undergoing cancer treatment. METHODS: Eight electronic databases including PubMed, Cochrane Library (including Cochrane Central Register of Controlled Trials [CENTRAL]), CINAHL Plus with Full Text, PsycINFO, MEDLINE, ProQuest, Science Direct and Scopus were searched to identify eligible randomised controlled trials from 1 January 2010 up to 9 April 2021. Search results were limited to &#039;children, adolescent and young adults&#039; 6-24 years undergoing cancer treatment. Randomised controlled studies in which technology-based psychosocial interventions were applied were examined. Of 4,927 articles, 12 articles met the inclusion criteria. Hedges&#039; g effect size was computed for each study. Effect sizes and moderator variables were tested using random-effects models. This study is registered with PROSPERO, number CRD42020177787. 

**RESULTS**
The outcomes were anger, anxiety, coping, depression, distress, quality of life and resilience. Compared with standard care, technology-based psychosocial interventions had a large effect and significantly on anger (g = -1.327, 95% CI: [-2.43, 0.22], anxiety (g = -0.89, 95%CI: [-1.34, -0.18], and depression (g = -1.05, 95% CI: [-1.65,-0.46]. Also, it was found that the duration of interventions had a significant moderator and effect size of the distress and resilience outcomes increased as the duration increased. 

**CONCLUSION**
This meta-analysis demonstrated that technology-based psychosocial interventions served as an effective intervention as it appears to have implications reducing anger, anxiety and depression in paediatric oncology. Nevertheless, randomised controlled studies with larger samples still needed to establish evidence-based psycho-oncological interventions for paediatric oncology. Future research should develop interventions more graduated by duration.
AN  - 34632662
AU  - Ozturk,
AU  - C.
AU  - S.
AU  - Toruner,
AU  - E.
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/ecc.13515
L1  - internal-pdf://3610367219/Ozturk-2021-Effectiveness of technology-based.pdf
PY  - 2021
SP  - e13515
T2  - European Journal of Cancer Care
TI  - Effectiveness of technology-based psychosocial interventions for child, adolescents and young adults undergoing cancer treatment: A meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34632662
UR  - https://onlinelibrary.wiley.com/doi/10.1111/ecc.13515
ER  -
TY  - JOUR
AB  - Premature mortality represents an important outcome for crime and violence prevention and related social interventions, but little is known about premature mortality in relation to these interventions. 

This article assesses the impact of interventions for at-risk and criminally involved youths and adults on premature mortality over the life-course. Systematic review methods are used, including comprehensive search strategies to identify, screen, and code eligible studies. Meta-analytic techniques are used to assess the impact of interventions on premature mortality, the influence of key moderators, and cause of mortality (natural vs. unnatural). 

A total of 11 studies met the inclusion criteria. Studies originated in five countries and were reported in the last two decades. Sample size can be considered large (&gt;500 participants) for all but two of the studies. Analysis of pooled effects showed a non-significant impact of interventions on premature mortality (OR= 0.89; 95% CI: 0.46, 1.74). Life-course stage, intervention type, and evaluation design did not moderate the mean effect. Of the nine studies that reported cause of mortality, interventions were associated with an increased likelihood of death by unnatural causes (OR = 1.78; 95% CI: 1.05, 2.39; p= .03). 

We conclude that greater attention needs to be paid to evaluating and understanding premature mortality over the life-course as part of the study of the effectiveness of crime and violence prevention interventions, and research opportunities exist to make an immediate contribution to this body of knowledge.
AN  - WOS:000723965100001
AU  - Welsh,
AU  - B.
AU  - C.
AU  - Zane,
AU  - S.
AU  - N.
AU  - Reeves,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40865-021-00185-5
L1  - internal-pdf://0859321023/Welsh-Impact of Interventions for At-Risk and.pdf
PY  - 2021
SP  - 22
T2  - Journal of Developmental and Life-Course Criminology
TI  - Impact of Interventions for At-Risk and Criminally Involved Youths and Adults on Premature Mortality over the Life-Course: a Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000723965100001
UR  - https://link.springer.com/content/pdf/10.1007/s40865-021-00185-5.pdf
ER  -
TY  - JOUR
AB  - Children with Autism Spectrum Disorder (ASD) often have deficits in motor skills, especially balance. 

This article presents a meta-analytic review of 15 intervention studies that aimed to improve balance in children and adolescents with ASD. Across these studies, there were 195 participants with ASD for whom pre-intervention and post-intervention balance scores were available. We measured the standardized mean difference (Hedges&#039; g) between their pre-intervention and post-intervention balance scores and found a large, positive effect from these balance interventions (standardized mean difference-1.82 (95% CI [1.34, 2.29])). 

Various balance intervention procedures were shown to be very efficacious for children and adolescents with ASD. Clearly, balance is a motor skill that is very susceptible to intervention efforts. We also provided recommendations to researchers regarding what information to include when conducting intervention studies.
AN  - 34936828
AU  - Djordjevic,
AU  - M.
AU  - Memisevic,
AU  - H.
AU  - Potic,
AU  - S.
AU  - Djuric,
AU  - U.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/00315125211060231
L1  - internal-pdf://2817268137/Djordjevic-2021-Exercise-Based Interventions A.pdf
PY  - 2021
SP  - 315125211060231
T2  - Perceptual &amp; Motor Skills
TI  - Exercise-Based Interventions Aimed at Improving Balance in Children with Autism Spectrum Disorder: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34936828
UR  - https://journals.sagepub.com/doi/pdf/10.1177/00315125211060231
ER  -
TY  - JOUR
AB  - The purpose of this meta-analysis was to summarize single-case design studies in which paraprofessionals delivered interventions to students with autism spectrum disorder in school settings. We descriptively analyzed participant and intervention characteristics and study quality and estimated intervention effect using Tau-U across student participants. Overall, paraprofessional-implemented interventions resulted in large to very large changes across a range of student outcomes and intervention conditions. Interventions delivered by paraprofessionals in inclusive school settings and within the context of whole group instructional arrangements resulted in significant changes in student outcomes as compared to interventions delivered in self-contained classrooms and within one-to-one and small group instructional arrangements. We present implications for research and practice and discuss limitations. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Walker, Virginia L.: virginia.walker@uncc.eduWalker, Virginia L.: Department of Special Education and Child Development, University of North Carolina at Charlotte, 9201 University City Blvd., Charlotte, NC, US, 28223, virginia.walker@uncc.eduWalker, Virginia L.: Department of Special Education and Child Development, University of North Carolina at Charlotte, Charlotte, NC, USCoogle, Christan Grygas: Division of Child, Family, and Community Engagement, George Mason University, Fairfax, VA, USLyon, Kristin J.: Kansas University Center on Developmental Disabilities (KUCDD), University of Kansas, Lawrence, KS, USTurf, Mindi: Department of Special Education, Illinois State University, Normal, IL, US
AN  - 2020-26576-001
AU  - Walker,
AU  - V.
AU  - L.
AU  - Coogle,
AU  - C.
AU  - G.
AU  - Lyon,
AU  - K.
AU  - J.
AU  - Turf,
AU  - M.
DA  - Apr
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/pits.22380
DP  - Ovid Technologies
KW  - autism spectrum disorder, meta- analysis, paraprofessional, single- case design
KW  - *Autism Spectrum Disorders
KW  - *Paraprofessional Personnel
KW  - *Special Education Students
KW  - *Students
KW  - *Group Intervention
KW  - Classrooms
KW  - Special &amp; Remedial Education [3570]
KW  - Human Adulthood (18 yrs &amp; older)
L1  - internal-pdf://3340703592/Walker-2021.pdf
LA  - English
M3  - Meta Analysis
PY  - 2021
SP  - 686-701
T2  - Psychology in the Schools
TI  - A meta-analytic review of paraprofessional-implemented interventions for students with autism spectrum disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-26576-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1002%2Fpits.22380&amp;issn=0033-3085&amp;isbn=&amp;volume=58&amp;issue=4&amp;spage=686&amp;pages=686-701&amp;date=2021&amp;title=Psychology+in+the+Schools&amp;atitle=A+meta-analytic+review+of+paraprofessional-implemented+interventions+for+students+with+autism+spectrum+disorder.&amp;aulast=Walker&amp;pid=%3Cauthor%3EWalker%2C+Virginia+L%3C%2Fauthor%3E%3CAN%3E2020-26576-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/10.1002/pits.22380
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pits.22380?download=true
VL  - 58
ER  -
TY  - JOUR
AB  - We conducted a meta-analysis which included 16 sibling-mediated intervention studies that aims to utilize siblings to teach their brothers and sisters with autism spectrum disorder play skills, functional skills, or to decrease unwanted behaviors. 

In general, results across the studies show that sibling-mediated intervention has medium effect size and can be used as a method to improve many skills which include social and communication skills. Sibling-mediated intervention also facilitated maintenance and generalization of the targeted skills.

The researchers discuss the findings and make suggestions for future investigations. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2021-45049-003
AU  - Bene,
AU  - K.
AU  - Lapina,
AU  - A.
DB  - Alerts 6_2022.enl
DO  - /10.1007/s40489-020-00212-z
L1  - internal-pdf://3861625563/Bene-2021-A meta-analysis of sibling-mediated.pdf
PY  - 2021
SP  - 186-194
T2  - Review Journal Of Autism And Developmental Disorders
TI  - A meta-analysis of sibling-mediated intervention for brothers and sisters who have autism spectrum disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2021-45049-003
UR  - https://link.springer.com/content/pdf/10.1007/s40489-020-00212-z.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **Background**
Mental health problems are a major health issue for children and adolescents around the world. The school environment allows adolescents to be reached comprehensively and on a low threshold, making it a potential environment for mental health interventions. 

The aim of this review was to describe interventions delivered by health-care workers in school environment for individual adolescents aged 12-18 with mental health problems and to assess the effectiveness of these interventions.
AN  - 34955926
AU  - Karukivi,
AU  - J.
AU  - Herrala,
AU  - O.
AU  - Sateri,
AU  - E.
AU  - Tornivuori,
AU  - A.
AU  - Salantera,
AU  - S.
AU  - Aromaa,
AU  - M.
AU  - Kronstrom,
AU  - K.
AU  - Karukivi,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2021.779933
L1  - internal-pdf://2342331151/fpsyt-12-779933.cleaned.pdf
PY  - 2021
SP  - 779933
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - The Effectiveness of Individual Mental Health Interventions for Depressive, Anxiety and Conduct Disorder Symptoms in School Environment for Adolescents Aged 12-18-A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34955926
VL  - 12
ER  -
TY  - JOUR
AB  - **Introduction:** 
Adolescent dating violence (ADV), including psychological, physical, threatening, and/or sexual abuse between adolescent romantic partners, is an epidemic in the United States, with youth report rates ranging from 15 to 77% for perpetration and 14-73% for victimization. ADV victimization is associated with multiple adverse outcomes in both adolescence and adulthood (e.g., suicidal ideation, substance use, bullying), as is ADV perpetration (e.g., sexually transmitted infections, intimate partner violence in adulthood). Given the high prevalence and profound impact of ADV on youth in the US, many prevention efforts have emerged in the past 20 years. Previous reviews of these efforts have focused primarily on school-based interventions or have broadly reviewed programs including all research design types and outcomes. This review is the first to provide a comprehensive, quantitative synthesis of all existing ADV prevention programs tested using randomized controlled trial designs with a control group, specifically measuring ADV perpetration and/or victimization as outcomes. 

**Method(s):** 
Employing a systematic literature search and screening protocol, nine studies were identified for meta-analysis. 

**Result(s):** 
Results indicate that ADV prevention programs may decrease the risk of emotional, physical, and sexual perpetration, as well as emotional and physical victimization. 

**Conclusion(s):** 
This is the first review to uncover significant intervention effects on the actual occurrence of ADV, with previous reviews only finding effects on outcomes such as ADV knowledge and attitude. Findings suggest that ADV prevention programs are promising and may warrant implementation more broadly with youth, and this review provides methodological suggestions for future research evaluating new ADV prevention programs. Copyright &copy; 2020 The Foundation for Professionals in Services for Adolescents
AD  - (Russell, Voith, Lee) Jack, Joseph, and Morton Mandel School of Applied Social Sciences at Case Western Reserve University, Cleveland, OH, United StatesK.N. Russell, Jack, Joseph, and Morton Mandel School of Applied Social Sciences at Case Western Reserve University, Cleveland, OH, United States. E-mail: knr25@case.edu
AN  - 2010589262
AU  - Russell,
AU  - K.
AU  - N.
AU  - Voith,
AU  - L.
AU  - A.
AU  - Lee,
AU  - H.
DA  - February
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.adolescence.2020.12.009
DP  - Ovid Technologies
KW  - Adolescent dating violence
KW  - Meta-analysis
KW  - Perpetration
KW  - Prevention
KW  - Randomized controlled trial
KW  - Victimization
KW  - adolescent
KW  - attitude
KW  - controlled study
KW  - dating violence
KW  - female
KW  - human
KW  - human experiment
KW  - juvenile
KW  - male
KW  - meta analysis
KW  - outcome assessment
KW  - quantitative analysis
KW  - randomized controlled trial (topic)
KW  - review
KW  - synthesis
KW  - systematic review
L1  - internal-pdf://0951496414/Russell-2021.pdf
LA  - English
M3  - Review
PY  - 2021
SP  - 6-14
T2  - Journal of Adolescence
TI  - Randomized controlled trials evaluating adolescent dating violence prevention programs with an outcome of reduced perpetration and/or victimization: A meta-analysis
UR  - http://www.elsevier.com/inca/publications/store/6/2/2/8/4/9/index.htt
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010589262
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.adolescence.2020.12.009&amp;issn=0140-1971&amp;isbn=&amp;volume=87&amp;issue=&amp;spage=6&amp;pages=6-14&amp;date=2021&amp;title=Journal+of+Adolescence&amp;atitle=Randomized+controlled+trials+evaluating+adolescent+dating+violence+prevention+programs+with+an+outcome+of+reduced+perpetration+and%2For+victimization%3A+A+meta-analysis&amp;aulast=Russell&amp;pid=%3Cauthor%3ERussell+K.N.%3C%2Fauthor%3E%3CAN%3E2010589262%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0140197120302037?via%3Dihub
VL  - 87
ER  -
TY  - JOUR
AB  - **Importance**: Self-harm and suicidal behavior are associated with substantial morbidity and mortality among children and adolescents. The comparative performance of psychotherapies for suicidality is unclear because few head-to-head clinical trials have been conducted. 

**Objective(s)**: To compare the efficacy of psychotherapies for the treatment of self-harm and suicidality among children and adolescents. Data Sources: Four major bibliographic databases (PubMed, MEDLINE, PsycINFO, and Embase) were searched for clinical trials comparing psychotherapy with control conditions from inception to September 2020. 

**Study Selection**: Randomized clinical trials comparing psychotherapies for suicidality and/or self-harm with control conditions among children and adolescents were included after a blinded review by 3 independent reviewers (A.B., M.P., and J.W.). 

**Data Extraction and Synthesis**: The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting guideline was followed for data abstraction, and the Cochrane risk of bias tool was used to evaluate study-level risk of bias. Data abstraction was performed by 1 reviewer (A.B.) and confirmed by 2 independent blinded reviewers (J.W. and M.P.). Data were analyzed from October 15, 2020, to February 15, 2021. 

**Main Outcomes and Measures**: The primary outcomes were dichotomized self-harm and retention in treatment. The secondary outcomes were dichotomized all-cause treatment discontinuation and scores on instruments measuring suicidal ideation and depressive symptoms. Effect sizes were pooled using frequentist random-effects network meta-analysis models to generate summary odds ratios (ORs) and Cohen d standardized mean differences (SMDs). Negative Cohen d SMDs or ORs less than 1 indicated that the treatment reduced the parameter of interest relative to the control condition (eg, signifying a beneficial association with suicidal ideation). 

**Result(s)**: The systematic search generated 1272 unique records. Of those, 44 randomized clinical trials (5406 total participants; 4109 female participants [76.0%]) from 49 articles were selected (5 follow-up studies were merged with their primary clinical trials to avoid publication bias). The selected clinical trials spanned January 1, 1995, to December 31, 2020. The median duration of treatment was 3 months (range, 0.25-12.00 months), and the median follow-up period was 12 months (range, 1-36 months). None of the investigated psychotherapies were associated with increases in study withdrawals or improvements in retention in treatment compared with treatment as usual. Dialectical behavioral therapies were associated with reductions in self-harm (OR, 0.28; 95% CI, 0.12-0.64) and suicidal ideation (Cohen d SMD, -0.71; 95% CI, -1.19 to -0.23) at the end of treatment, while mentalization-based therapies were associated with decreases in self-harm (OR, 0.38; 95% CI, 0.15-0.97) and suicidal ideation (Cohen d SMD, -1.22; 95% CI, -2.18 to -0.26) at the end of follow-up. The quality of evidence was downgraded because of high risk of bias overall, heterogeneity, publication bias, inconsistency, and imprecision. 

**Conclusions and Relevance**: Although some psychotherapeutic modalities appear to be acceptable and efficacious for reducing self-harm and suicidality among children and adolescents, methodological issues and high risk of bias prevent a consistent estimate of their comparative performance. Copyright &copy; 2021 Georg Thieme Verlag. All rights reserved.
AD  - (Bahji, Ortega, Patten) Department of Psychiatry, University of Calgary, 2500 University Dr NW, Calgary, AB T2N 1N4, Canada (Pierce, Wong, Roberge) Department of Psychiatry, Queen&#039;s University, Kingston, ON, Canada (Pierce, Wong, Roberge) Division of Child and Youth Mental Health, Queen&#039;s University, Kingston, ON, Canada (Patten) Department of Community Health Sciences, University of Calgary, Calgary, AB, CanadaA. Bahji, Department of Psychiatry, University of Calgary, 2500 University Dr NW, Calgary, AB T2N 1N4, Canada. E-mail: anees.bahji1@ucalgary.ca
AN  - 634774168
AU  - Bahji,
AU  - A.
AU  - Pierce,
AU  - M.
AU  - Wong,
AU  - J.
AU  - Roberge,
AU  - J.
AU  - N.
AU  - Ortega,
AU  - I.
AU  - Patten,
AU  - S.
DA  - 16 Apr
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1001/jamanetworkopen.2021.6614
DP  - Ovid Technologies
KW  - adolescent
KW  - adult
KW  - article
KW  - automutilation/th [Therapy]
KW  - bibliographic database
KW  - child
KW  - comparative effectiveness
KW  - depression
KW  - dialectical behavior therapy
KW  - female
KW  - follow up
KW  - human
KW  - male
KW  - mentalization-based treatment
KW  - meta analysis
KW  - priority journal
KW  - program acceptability
KW  - psychotherapy
KW  - randomized controlled trial (topic)
KW  - suicidal behavior/th [Therapy]
KW  - suicidal ideation
KW  - suicide attempt
KW  - systematic review
L1  - internal-pdf://4134743284/Bahji-2021.pdf
LA  - English
PY  - 2021
T2  - JAMA Network Open
TI  - Comparative Efficacy and Acceptability of Psychotherapies for Self-harm and Suicidal Behavior among Children and Adolescents: A Systematic Review and Network Meta-analysis
UR  - https://jamanetwork.com/journals/jamanetworkopen
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=634774168
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33861328&amp;id=doi:10.1001%2Fjamanetworkopen.2021.6614&amp;issn=2574-3805&amp;isbn=&amp;volume=4&amp;issue=4&amp;spage=e216614&amp;pages=&amp;date=2021&amp;title=JAMA+Network+Open&amp;atitle=Comparative+Efficacy+and+Acceptability+of+Psychotherapies+for+Self-harm+and+Suicidal+Behavior+among+Children+and+Adolescents%3A+A+Systematic+Review+and+Network+Meta-analysis&amp;aulast=Bahji&amp;pid=%3Cauthor%3EBahji+A.%3C%2Fauthor%3E%3CAN%3E634774168%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2778571/bahji_2021_oi_210217_1617752037.87001.pdf
VL  - 4 (4) (no pagination)
ER  -
TY  - JOUR
AB  - **Objective**. Although increasing evidence reveals the efficacy of traditional Chinese medicine (TCM) and its safety on Tourette Syndrome (TS) patients, whether TCM is indeed improving TS remains unclear. The purpose of the current study is to perform a meta-analysis to evaluate the efficacy and safety of TCM on treating TS patients. 

**Method**. An elaborate search strategy was conducted based on several databases including Medline, Embase, Cochrane, Web of Science, CINAHL, CBM, VIP, CNKI, and Wanfang Data in order to identify the relevant randomized controlled trials (RCTs) from their inception to as late as May 1st, 2020. General information and data needing analysis were extracted simultaneously for the necessity of various analyses such as descriptive analysis and metaquantitative analysis. 

**Results**. Forty-seven trials with 5437 TS patients in total were eventually included according to our criteria. All trials were conducted in China, and the publication years ranged from 2004 to 2017. In terms of clinical efficacy, clinical symptoms of patients with TCM were more likely to be improved compared with the control group (odds ratio, OR=-1.29, 95% confidence interval, CI: -2.54 to -0.06, I2=0.00%). As to the outcome of recurrence rate, the pooled results revealed that the TCM group was more inclined to stabilize the recurrence (OR=0.44, 95% CI: 0.24 to 0.78, I2=0.00%). Similar results were observed in adverse reaction (OR=0.32, 95% CI: 0.24 to 0.43, I2=32.90%). 

**Conclusion**. The results of our study recommend applying TCM to treat TS patients for better efficacy and safety. Results need to be interpreted cautiously due to certain limitations in our study. Copyright &copy; 2021 Na Wang et al.
AN  - 2011493464
AU  - Wang,
AU  - N.
AU  - Qin,
AU  - D.
AU  - D.
AU  - Xie,
AU  - Y.
AU  - H.
AU  - Wu,
AU  - X.
AU  - C.
AU  - Wang,
AU  - D.
AU  - Y.
AU  - Hang,
AU  - Yang
AU  - Li,
AU  - X.
AU  - X.
AU  - Xiong,
AU  - L.
AU  - Liang,
AU  - J.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1155/2021/6630598
L1  - internal-pdf://1514336386/Wang-2021-Traditional Chinese Medicine Strateg.pdf
PY  - 2021
T2  - BioMed Research International
TI  - Traditional Chinese Medicine Strategy for Patients with Tourette Syndrome Based on Clinical Efficacy and Safety: A Meta-Analysis of 47 Randomized Controlled Trials
UR  - http://www.hindawi.com/journals/biomed/
UR  - https://downloads.hindawi.com/journals/bmri/2021/6630598.pdf
VL  - 2021 (no pagination)
ER  -
TY  - JOUR
AB  - Anxiety disorders are common in adolescence but outcomes for adolescents are unclear and we do not know what factors moderate treatment outcome for this age group. We conducted meta-analyses to establish the effectiveness of psychological therapies for adolescent anxiety disorders in (i) reducing anxiety disorder symptoms, and (ii) remission from the primary anxiety disorder, compared with controls, and examine potential moderators of treatment effects. The protocol was registered with PROSPERO (CRD42018091744).

Electronic databases (Web of Science, MEDLINE, Psycinfo, EMBASE) were searched from January 1990 to December 2019. 2511 articles were reviewed, those meeting strict criteria were included. Random effects meta-analyses were conducted. Analyses of symptom severity outcomes comprised sixteen studies (CBT k = 15, non-CBT k = 1; n = 766 adolescents), and analyses of diagnostic remission outcomes comprised nine (CBT k = 9; n = 563 adolescents). 

Post-treatment, those receiving treatment were significantly more likely to experience reduced symptom severity (SMD = 0.454, 95% CI 0.22-0.69) and remission from the primary anxiety disorder than controls (RR = 7.94, 95% CI 3.19-12.7) (36% treatment vs. 9% controls in remission). None of the moderators analysed were statistically significant. 

Psychological therapies targeting anxiety disorders in adolescents are more effective than controls. However, with only just over a third in remission post-treatment, there is a clear need to develop more effective treatments for adolescents, evaluated through high-quality randomised controlled trials incorporating active controls and follow-up data. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-82416-001
AU  - Baker,
AU  - H.
AU  - J.
AU  - Lawrence,
AU  - P.
AU  - J.
AU  - Karalus,
AU  - J.
AU  - Creswell,
AU  - C.
AU  - Waite,
AU  - P.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s10567-021-00364-2
L1  - internal-pdf://1092753552/Baker-2021-The effectiveness of psychological.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Clinical Child and Family Psychology Review
TI  - The effectiveness of psychological therapies for anxiety disorders in adolescents: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-82416-001
UR  - https://link.springer.com/content/pdf/10.1007/s10567-021-00364-2.pdf
ER  -
TY  - JOUR
AB  - **Objectives** Theta burst stimulation (TBS) is often used in clinical practice and research protocols for adults with neuropsychiatric disorders. There are substantial knowledge gaps related to the application of TBS in children and adolescents. This systematic review examined the safety and tolerability of TBS in children and adolescents. 

**Materials and Methods** A systematic review of human TBS studies in children and adolescents was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The following inclusion criteria were applied: 1) articles in English language only; 2) studies that included child and adolescent participants (up to 21 years of age); 3) studies that administered intermittent TBS or continuous TBS or both to participants; 4) studies that had an outcome measure; and 5) availability of full text material. The primary outcome measures were tolerability and safety. When feasible, the clinical effects were reviewed. 

**Results** Twenty relevant articles met the criteria for inclusion. The reported adverse events were mild and similar to what is noted in adult studies. The most common symptom was headache. One case report described a seizure induced by TBS. Collectively, the studies were heterogeneous but the methodologic quality of randomized trials was high. 

**Conclusions** TBS interventions in children may have similar safety, tolerability, and feasibility as compared to adults. However, long-term, follow-up studies of TBS are lacking. Future dose-ranging studies with systematic assessment of adverse events will be important in the translation of findings with TBS from adults to youth.
AN  - WOS:000654451900001
AU  - Elmaghraby,
AU  - R.
AU  - Sun,
AU  - Q.
AU  - Ozger,
AU  - C.
AU  - Shekunov,
AU  - J.
AU  - Romanowicz,
AU  - M.
AU  - Croarkin,
AU  - P.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/ner.13455
L1  - internal-pdf://1971817811/Elmaghraby-A Systematic Review of the Safety a.pdf
PY  - 2021
SP  - 9
T2  - Neuromodulation
TI  - A Systematic Review of the Safety and Tolerability of Theta Burst Stimulation in Children and Adolescents
UR  - &lt;Go to ISI&gt;://WOS:000654451900001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ner.13455?download=true
ER  -
TY  - JOUR
AB  - The fear of being in the focus of attention in social situations can develop into a social anxiety disorder (SAD). The classical treatment for SAD is cognitive behavioral therapy, which is in many cases accompanied by drug treatments. A promising alternative treatment is physical activity (PA) interventions, because regular PA has been shown to be suitable for reducing anxiety in general. 

We conducted a pre-registered systematic review and meta-analysis (PROSPERO registration no. CRD42020191181) as well as two additional searches. Our aim was to investigate whether PA interventions are a suitable treatment for SAD and whether PA is suitable for reducing social anxiety (SA) in general. For studies with randomized controlled trial designs, a not statistically significant effect of medium size toward lower general SA symptomatology was found in the PA group in comparison with the control group (d = -0.24, p = 0.377). For studies with longitudinal designs, significantly lower SA symptoms were found after PA treatments (d = -0.22, p = 0.001). The effect of PA on SA was stronger for adults than for children and adolescents (p = 0.003). For cross-sectional studies, a small negative association between SA symptoms and the amount of PA was found, i.e., lower SA was found for people who were more physically active (r = -0.12, p = 0.003). 

We conclude that PA is a promising means for the (additional) treatment of SAD or to reduce SA in general in non-clinical samples, but more research in which high-quality studies with randomized controlled trial designs are used is needed. Furthermore, open questions with respect to moderating variables (e.g., age, sex, BMI, type of intervention, stress, amount of regular PA before the intervention, and comorbidities) remain still open.
AN  - 34177489
AU  - Zika,
AU  - M.
AU  - A.
AU  - Becker,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fnhum.2021.653108
L1  - internal-pdf://0116849785/Zika-2021-Physical Activity as a Treatment for.pdf
PY  - 2021
SP  - 653108
T2  - Frontiers in Human Neuroscience
TI  - Physical Activity as a Treatment for Social Anxiety in Clinical and Non-clinical Populations: A Systematic Review and Three Meta-Analyses for Different Study Designs
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34177489
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230570/pdf/fnhum-15-653108.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Prolonged viewing of screen-based media is associated with poor sleep in children. Previous systematic reviews have analysed the effectiveness of interventions that aim to limit children&#039;s screen use; however, none have evaluated its effect on sleep. 

The aim of this systematic review was to evaluate the effect of interventions that incorporate strategies to control children&#039;s screen use on screen use and sleep. The databases Pubmed, Embase, Eric, Scopus and PsycInfo were searched during October 2017 and updated in February 2019 for experimental studies with a control that assessed interventions to control screen use in children aged 2-14 years and reported both screen use and sleep outcomes. From 3,872 initial records, 11 studies (six randomized control [RCT], four cluster RCT and one cluster, quasi-experimental) were eligible for inclusion. 

A total of 4,656 children aged 2-13 years were included in the studies. The mean reduction in screen time was 0.56 hr (33 min)/day (95% confidence interval [CI], 0.92, 0.20) and the mean sleep duration increased by 0.19 hr (11 min)/day (95% CI, 0.05, 0.33). Bedtime was advanced by 0.16 hr (10 min) on weekdays and by 1.0 hr at the weekend. Subgroup analyses indicated stronger intervention effects for interventions of shorter duration (&lt;3 months), which specifically targeted screen use or sleep, and those with direct participant contact. In conclusion, small improvements in screen time and sleep duration can be achieved in children. 

It is not possible to determine if a reduction in screen time directly improves sleep, due to the limited number of studies, the presence of co-interventions, issues with studies&#039; methodological quality and heterogeneity. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2020-45085-001
AU  - Martin,
AU  - Katie
AU  - B.
AU  - Bednarz,
AU  - Jana
AU  - M.
AU  - Aromataris,
AU  - Edoardo
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jsr.13130
L1  - internal-pdf://3826827448/Martin-2021-Interventions to control children&#039;.pdf
PY  - 2021
T2  - Journal of Sleep Research Vol 30(3), 2021, ArtID e13130
TI  - Interventions to control children&#039;s screen use and their effect on sleep: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-45085-001
UR  - https://onlinelibrary.wiley.com/doi/10.1111/jsr.13130
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jsr.13130?download=true
VL  - 30
ER  -
TY  - JOUR
AB  - Needle-related procedures are often a source of pain, anxiety and fear in young patients. This systematic review aimed to investigate the effectiveness of virtual reality (VR) on reducing pain, fear and anxiety in pediatric patients undergoing needle-related procedures. Pain, anxiety, fear, changes in blood pressure and heart rate as well as satisfaction were evaluated as outcomes during needle-related procedures in VR compared with standard care conditions. 

A meta-analysis was performed, taking into account online databases. Two authors independently conducted literature searches in December 2020. The last search was conducted in March 2021 from a total of 106 records, 7 met our inclusion criteria. One study was excluded from the meta-analysis due to insufficient data. VR was applied as a distractor during venous access. Statistically significant benefits of using VR were shown in children&#039;s pain scores, where VR significantly decreased symptoms (n = 3204 patients, MD = -2.85; 95% CI -3.57, -2.14, for the Wong-Baker Faces Pain Rating Scale and n = 2240 patients, MD = -0.19; 95% CI -0.58, 0.20, for the Faces Pain Scale-Revised). The analysis of fear, anxiety and satisfaction scores revealed no significant differences between the conditions, as the studies were too heterogeneous to be pooled. 

Distraction using virtual reality may be an effective intervention for reducing pain in children undergoing needle-related medical procedures. However, further research in the implementation of VR as a distractor for children and adolescents is required, due to the limited research into this field. Copyright &copy; 2021 by the authors. Licensee MDPI, Basel, Switzerland.
AN  - 2007878279
AU  - Czech,
AU  - O.
AU  - Wrzeciono,
AU  - A.
AU  - Rutkowska,
AU  - A.
AU  - Guzik,
AU  - A.
AU  - Kiper,
AU  - P.
AU  - Rutkowski,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/jcm10153248
L1  - internal-pdf://3106764963/Czech-2021-Virtual reality interventions for n.pdf
PY  - 2021
T2  - Journal of Clinical Medicine
TI  - Virtual reality interventions for needle-related procedural pain, fear and anxiety-a systematic review and meta-analysis
UR  - https://www.mdpi.com/2077-0383/10/15/3248/pdf
UR  - https://res.mdpi.com/d_attachment/jcm/jcm-10-03248/article_deploy/jcm-10-03248.pdf
VL  - 10 (15) (no pagination)
ER  -
TY  - JOUR
AB  - **ABSTRACT** This systematic review and meta-analysis aims to provide a comprehensive evaluation of randomized controlled trials of psychoeducational group interventions targeting anxiety symptoms in youths. We systematically searched for articles and located twelve studies that collectively included 1132 subjects. Analyses showed an overall effect of -0.47 (95% CI -0.75 to -0.19) on the Standardized Mean Difference (SMD) scale, suggesting that psychoeducation effectively reduces anxiety symptoms in children and adolescents. However, the I 2 index was 86.4% revealing the presence of substantial heterogeneity. These results suggest that psychoeducation may be a promising alternative for the prevention and/or treatment of anxiety disorders in youths. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-71242-001
AU  - Baourda,
AU  - V.
AU  - C.
AU  - Brouzos,
AU  - A.
AU  - Mavridis,
AU  - D.
AU  - Vassilopoulos,
AU  - S.
AU  - P.
AU  - Vatkali,
AU  - E.
AU  - Boumpouli,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/01933922.2021.1950881
L1  - internal-pdf://2618827075/Baourda-2021-Group psychoeducation for anxiety.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Journal for Specialists in Group Work
TI  - Group psychoeducation for anxiety symptoms in youth: Systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-71242-001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/01933922.2021.1950881?needAccess=true
ER  -
TY  - JOUR
AB  - **Background: **
Social, emotional, and behavioral problems in childhood are key predictors of persistent problem behaviors throughout the life courses of individuals. Early parental intervention training, as an important preventive measure, plays a critical role in improving the social, emotional, and behavioral (SEB) development of children.

**Method: **
We conducted a systematic review and meta-analysis to analyze the intervention effects of the latest literature on Triple P (Positive Parenting Program), which is a multilevel system that provides treatment and prevention for children at risk of social, emotional, and behavioral problems via parenting approaches to enhance the parenting knowledge, skills, and confidence of parents. Since the literature on Triple P from 1970 to 2012 has already been systematically reviewed, this study searched the literature from 2013 to 2020 from the Web of Science, EBSCO, ERIC, MEDLINE, CNKI, and Triple P Evidence-Base website using multiple search strategies. This study differs from the existing research by its inclusion criteria of studies that use experimental designs or quasi-experimental designs. A total of 37 studies were included in the final analysis, and STATA 16.0 was used for evaluation while RevMan 5.3 for risk of bias assessment.

**Results:** 
The results show that Triple P can promote the social competence of children (SMD = 0.274) and prevent their emotional (SMD = &minus;0.254) and behavioral problems (SMD = &minus;1.38) to a certain extent. Simultaneously, the proximal effects on parents mainly included changing negative parenting styles (SMD = &minus;0.46), reducing parenting conflicts (SMD = &minus;0.311), and improving parenting efficacy and self-confidence (SMD = 0.419). The distal effects on parents included reducing the psychological adjustment problems of parents (SMD = &minus;0.265), improving parent&ndash;child relationships, and reducing parent&ndash;child conflict (SMD = &minus;0.714). However, the meta-analysis results did not show a significant effect of Triple P on improving the marital relationship quality and satisfaction of parents (SMD = 0.063). Components of the program intervention, including intervention level, service delivery format, service method, and program implementation setting, and the age of the children were crucial moderating factors on the outcomes of Triple P.

**Conclusion:** 
This study systematically reviewed the latest Triple P intervention literature and found the significant effectiveness of Triple P on the SEB problems of children and parenting outcomes and the moderators of the effect size.
AN  - 34512467
AU  - Li,
AU  - N.
AU  - Peng,
AU  - J.
AU  - Li,
AU  - Y.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyg.2021.709851
L1  - internal-pdf://2191664966/Li-2021-Effects and Moderators of Triple P on.pdf
PY  - 2021
SP  - 709851
T2  - Frontiers in Psychology
TI  - Effects and Moderators of Triple P on the Social, Emotional, and Behavioral Problems of Children: Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34512467
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427298/pdf/fpsyg-12-709851.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Attention Deficit Hyperactivity Disorder (ADHD) can be associated with limited understanding of the condition and poor social skills. Some evidence favors a psychoeducational approach, but little is known about the effectiveness of psychoeducation.

**METHODS**: Systematic review and meta-analysis of studies assessing psychoeducational interventions that aim to improve social skills of young people with ADHD.

**RESULTS**: Ten studies, including 943 participants, reported across 13 papers met the inclusion criteria. Although effect sizes were small, findings suggest the included interventions significantly improved social skills in young people with ADHD.

**CONCLUSIONS**: Results show promise for psychoeducational behavioral interventions . However, the recommendations that can be developed from existing evidence are somewhat limited by the low quality of studies. Further rigorous trials are needed. In addition, future research should consider the long-term outcomes for these interventions, they should be iteratively co-designed and research should consider the context they intend to be delivered in.
AD  - Powell, Lauren Amy. University of Sheffield, Sheffield, UK.Parker, Jack. University of Derby, Derby, UK.Weighall, Anna. University of Sheffield, Sheffield, UK.Harpin, Valerie. Ryegate Children&#039;s Centre, Sheffield Children&#039;s NHS Foundation Trust, Sheffield, UK.
AN  - 33666104
AU  - Powell,
AU  - L.
AU  - A.
AU  - Parker,
AU  - J.
AU  - Weighall,
AU  - A.
AU  - Harpin,
AU  - V.
DA  - Mar 05
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1087054721997553
DP  - Ovid Technologies
J2  - J Atten Disord
L1  - internal-pdf://3027574677/Powell-2021-Psychoeducation Intervention Effec.pdf
LA  - English
N1  - Powell, Lauren AmyParker, JackWeighall, AnnaHarpin, Valerie
PY  - 2021
SP  - 1087054721997553
T2  - Journal of Attention Disorders
TI  - Psychoeducation Intervention Effectiveness to Improve Social Skills in Young People with ADHD: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33666104
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33666104&amp;id=doi:10.1177%2F1087054721997553&amp;issn=1087-0547&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1087054721997553&amp;pages=1087054721997553&amp;date=2021&amp;title=Journal+of+Attention+Disorders&amp;atitle=Psychoeducation+Intervention+Effectiveness+to+Improve+Social+Skills+in+Young+People+with+ADHD%3A+A+Meta-Analysis.&amp;aulast=Powell&amp;pid=%3Cauthor%3EPowell+LA%3C%2Fauthor%3E%3CAN%3E33666104%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1087054721997553
ER  -
TY  - JOUR
AB  - **Background** It has been suggested that low serum zinc levels may be associated with suboptimal outcomes of pregnancy, such as prolonged labour, atonic postpartum haemorrhage, pregnancy‐induced hypertension, preterm labour and post‐term pregnancies, although these associations have not yet been established. This is an update of a review first published in 1997 and subsequently updated in 2007, 2012 and 2015.

**Objectives**. 1.To compare the effects on maternal, fetal, neonatal and infant outcomes in healthy pregnant women receiving zinc supplementation versus no zinc supplementation, or placebo.2. To assess the above outcomes in a subgroup analysis reviewing studies performed in women who are, or are likely to be, zinc‐deficient.

**Search methods** For this update, we searched Cochrane Pregnancy and Childbirth&rsquo;s Trials Register, ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform (ICTRP) (3 July 2020), and reference lists of retrieved studies.Selection criteria Randomised trials of zinc supplementation versus no zinc supplementation or placebo administration during pregnancy, earlier than 27 weeks&#039; gestation. We excluded quasi‐randomised controlled trials. We intended to include studies presented only as abstracts, if they provided enough information or, if necessary, by contacting authors to analyse them against our criteria; we did not find any such studies. Data collection and analysis. Three review authors applied the study selection criteria, assessed trial quality and extracted data. When necessary, we contacted study authors for additional information. We assessed the certainty of the evidence using GRADE.

**Main results** For this update, we included 25 randomised controlled trials (RCTs) involving over 18,000 women and their babies. The overall risk of bias was low in half of the studies. The evidence suggests that zinc supplementation may result in little or no difference in reducing preterm births (risk ratio (RR) 0.87, 95% confidence interval (CI) 0.74 to 1.03; 21 studies, 9851 participants; low‐certainty evidence). Further, zinc supplementation may make little or no difference in reducing the risk of stillbirth (RR 1.22, 95% CI 0.80 to 1.88; 7 studies, 3295 participants; low‐certainty evidence), or perinatal deaths (RR 1.10, 95% CI 0.81 to 1.51; 2 studies, 2489 participants; low‐certainty evidence). It is unclear whether zinc supplementation reduces neonatal death, because the certainty of the evidence is very low. Finally, for other birth outcomes, zinc supplementation may make little or no difference to mean birthweight (MD 13.83, 95% CI ‐15.81 to 43.46; 22 studies, 7977 participants; low‐certainty evidence), and probably makes little or no difference in reducing the risk of low birthweight (RR 0.94, 95% CI 0.79 to 1.13; 17 studies, 7399 participants; moderate‐certainty evidence) and small‐for‐gestational age babies when compared to placebo or no zinc supplementation (RR 1.02, 95% CI 0.92 to 1.12; 9 studies, 5330 participants; moderate‐certainty evidence). We did not conduct subgroup analyses, as very few studies used normal zinc populations.

**Authors&#039; conclusions** There is not enough evidence that zinc supplementation during pregnancy results in improvements in maternal or neonatal outcomes. Future research to address ways of improving the overall nutritional status of pregnant women, particularly in low‐income regions, and not looking at zinc in isolation, should be an urgent priority.
AU  - Carducci,
AU  - B.
AU  - Keats.
AU  - E.
AU  - C.
AU  - Bhutta,
AU  - Z.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD000230.pub6
L1  - internal-pdf://1979392484/Carducci_et_al-2021-Cochrane_Database_of_Syste.pdf
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - Zinc supplementation for improving pregnancy and infant outcome
ER  -
TY  - JOUR
AB  - Evidence suggests that cyberbullying among school-age children is related to problem behaviors and other adverse school performance constructs. As a result, numerous school-based programs have been developed and implemented to decrease cyberbullying perpetration and victimization. Given the extensive literature and variation in program effectiveness, we conducted a comprehensive systematic review and meta-analysis of programs to decrease cyberbullying perpetration and victimization. Our review included published and unpublished literature, utilized modern, transparent, and reproducible methods, and examined confirmatory and exploratory moderating factors. A total of 50 studies and 320 effect sizes spanning 45,371 participants met the review protocol criteria. Results indicated that programs significantly reduced cyberbullying perpetration (g = -0.18, SE = 0.05, 95% CI [-0.28, -0.09]) and victimization (g = -0.13, SE = 0.04, 95% CI [-0.21, -0.05]). Moderator analyses, however, yielded only a few statistically significant findings. We interpret these findings and provide implications for future cyberbullying prevention policy and practice.
AN  - WOS:000664423400002
AU  - Polanin,
AU  - J.
AU  - R.
AU  - Espelage,
AU  - D.
AU  - L.
AU  - Grotpeter,
AU  - J.
AU  - K.
AU  - Ingram,
AU  - K.
AU  - Michaelson,
AU  - L.
AU  - Spinney,
AU  - E.
AU  - Valido,
AU  - A.
AU  - El
AU  - Sheikh,
AU  - A.
AU  - Torgal,
AU  - C.
AU  - Robinson,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s11121-021-01259-y
L1  - internal-pdf://4092055483/Polanin-A Systematic Review and Meta-analysis.pdf
PY  - 2021
SP  - 16
T2  - Prevention Science
TI  - A Systematic Review and Meta-analysis of Interventions to Decrease Cyberbullying Perpetration and Victimization
UR  - &lt;Go to ISI&gt;://WOS:000664423400002
UR  - https://link.springer.com/content/pdf/10.1007/s11121-021-01259-y.pdf
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Mental health problems in children and young people are common and can lead to poor long-term outcomes. Despite the availability of effective psychological interventions for mental health disorders, only a minority of affected children and young people access treatment. Digital interventions, such as applied games and virtual reality (VR), that target mental health problems in children and young people may hold a key to increasing access to, engagement with, and potentially the effectiveness of psychological treatments. To date, several applied games and VR interventions have been specifically developed for children and young people. This systematic review aims to identify and synthesize current data on the experience and effectiveness of applied games and VR for targeting mental health problems in children and young people (defined as average age of 18 years or below).

**METHODS**: Electronic systematic searches were conducted in Medline, PsycINFO, CINAHL, and Web of Science.

**RESULTS**: Nineteen studies were identified that examined nine applied games and two VR applications, and targeted symptoms of anxiety, depression, and phobias using both quantitative and qualitative methodologies. Existing evidence is at a very early stage and studies vary extensively in key methodological characteristics. For applied games, the most robust evidence is for adolescent depressive symptoms (medium clinical effect sizes). Insufficient research attention has been given to the efficacy of VR interventions in children and young people.

**CONCLUSIONS**: The evidence to date is at a very early stage. Despite the enthusiasm for applied games and VR, existing interventions are limited in number and evidence of efficacy, and there is a clear need for further co-design, development, and evaluation of applied games and VR before they are routinely offered as treatments for children and young people with mental health problems.
AD  - Halldorsson, Brynjar. Department of Experimental Psychology, University of Oxford, Oxford, UK.Halldorsson, Brynjar. Department of Psychiatry, University of Oxford, Oxford, UK.Halldorsson, Brynjar. Department of Psychology, Reykjavik University, Reykjavik, Iceland.Hill, Claire. School of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.Waite, Polly. Department of Experimental Psychology, University of Oxford, Oxford, UK.Waite, Polly. Department of Psychiatry, University of Oxford, Oxford, UK.Waite, Polly. School of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.Partridge, Kate. CAMHS Anxiety and Depression Pathway, Berkshire Healthcare Foundation Trust, University of Reading, Reading, UK.Freeman, Daniel. Department of Psychiatry, University of Oxford, Oxford, UK.Freeman, Daniel. Oxford Health NHS Foundation Trust, Oxford, UK.Creswell, Cathy. Department of Experimental Psychology, University of Oxford, Oxford, UK.Creswell, Cathy. Department of Psychiatry, University of Oxford, Oxford, UK.
AN  - 33655534
AU  - Halldorsson,
AU  - B.
AU  - Hill,
AU  - C.
AU  - Waite,
AU  - P.
AU  - Partridge,
AU  - K.
AU  - Freeman,
AU  - D.
AU  - Creswell,
AU  - C.
DA  - Mar 02
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13400
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
L1  - internal-pdf://1460213748/Halldorsson-2021-Immersive virtual reality and.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingMarHalldorsson, BrynjarHill, ClaireWaite, PollyPartridge, KateFreeman, DanielCreswell, Cathy
PY  - 2021
SP  - 02
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Immersive virtual reality and digital applied gaming interventions for the treatment of mental health problems in children and young people: the need for rigorous treatment development and clinical evaluation
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33655534
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33655534&amp;id=doi:10.1111%2Fjcpp.13400&amp;issn=0021-9630&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Immersive+virtual+reality+and+digital+applied+gaming+interventions+for+the+treatment+of+mental+health+problems+in+children+and+young+people%3A+the+need+for+rigorous+treatment+development+and+clinical+evaluation.&amp;aulast=Halldorsson&amp;pid=%3Cauthor%3EHalldorsson+B%3C%2Fauthor%3E%3CAN%3E33655534%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.13400?download=true
VL  - 02
ER  -
TY  - JOUR
AB  - One of the most studied aspects of children&#039;s cognitive development is that of the development of the executive function, and research has shown that physical activity has been demonstrated as a key factor in its enhancement. 

This meta-analysis aims to assess the impact of specific sports interventions on the executive function of children and teenagers. A systematic review was carried out on 1 November 2020 to search for published scientific evidence that analysed different sports programs that possibly affected executive function in students. Longitudinal studies, which assessed the effects of sports interventions on subjects between 6 and 18 years old, were identified through a systematic search of the four principal electronic databases: Web of Science, PubMed, Scopus, and EBSCO. 

A total of eight studies, with 424 subjects overall, met the inclusion criteria and were classified based on one or more of the following categories: working memory, inhibitory control, and cognitive flexibility. The random-effects model for meta-analyses was performed with RevMan version 5.3 to facilitate the analysis of the studies. Large effect sizes were found in all categories: working memory (ES -1.25; 95% CI -1.70; -0.79; p &lt; 0.0001); inhibitory control (ES -1.30; 95% CI -1.98; -0.63; p &lt; 0.00001); and cognitive flexibility (ES -1.52; 95% CI -2.20; -0.83; p &lt; 0.00001). 

Our analysis concluded that healthy children and teenagers should be encouraged to practice sports in order to improve their executive function at every stage of their development. Copyright &copy; 2021 by the authors. Licensee MDPI, Basel, Switzerland.
AN  - 2007517329
AU  - Contreras-Osorio,
AU  - F.
AU  - Campos-Jara,
AU  - C.
AU  - Martinez-Salazar,
AU  - C.
AU  - Chirosa-Rios,
AU  - L.
AU  - Martinez-Garcia,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/brainsci11060755
L1  - internal-pdf://0386495846/Contreras-Osori-2021-Effects of sport-based in.pdf
PY  - 2021
T2  - Brain Sciences
TI  - Effects of sport-based interventions on children&#039;s executive function: A systematic review and meta-analysis
UR  - https://www.mdpi.com/2076-3425/11/6/755/pdf
UR  - https://res.mdpi.com/d_attachment/brainsci/brainsci-11-00755/article_deploy/brainsci-11-00755.pdf
VL  - 11 (6) (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Up to 60% of pediatric surgical patients develop high levels of preoperative anxiety. This study compared the effects of oral combinations of midazolam and ketamine with oral midazolam alone for pediatric preanesthetic medication. 

**METHODS**: The study protocol was registered in PROSPERO as CRD42020172920. A systematic literature search was conducted using Medline, Cochrane, EMBASE, CENTRAL, and Web of Science for randomized controlled trials comparing oral combinations of midazolam and ketamine with midazolam alone as preanesthetic medication in elective surgical pediatric patients. Meta-analyses included the following outcomes: anxiety and sedation levels, child&#039;s behavior during separation from parents, face mask acceptance, and venipuncture. The quality of evidence was assessed using GRADE criteria. 

**RESULTS**: Twenty studies were included. The following effects (RR (95% CI)) were observed for combinations of ketamine and midazolam relative midazolam alone: anxiolysis (1.2 (0.94-1.52); p = 0.15; I2 = 80%; GRADE = very low); satisfactory sedation (1.2 ( 1.10-1.31); p &lt; 0.001; I2 = 71%; GRADE = very low); behavior during parental separation (1.2 (1.06-1.36); p = 0.003; I2 = 88%; GRADE = very low); facial mask acceptance (1.13 (1.04-1.24); p = 0.007; I2 = 49%; GRADE = very low); behavior during venipuncture (1.32 (1.11-1.57); p = 0.002; I2 = 66%; GRADE = very low). 

**CONCLUSIONS**: While similar probabilities of obtaining anxiolysis were found, adequate sedation, calm behavior during child&#039;s separation from parents, low levels of fear during face mask adaptation, and cooperative behavior during peripheral venous cannulation were more likely with midazolam-ketamine combinations.
AN  - 34411631
AU  - Oliveira
AU  - Filho,
AU  - G.
AU  - R.
AU  - Castilhos,
AU  - C.
AU  - M.
AU  - Kriegl,
AU  - J.
AU  - P.
AU  - Bianchi,
AU  - G.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.bjane.2021.07.026
L1  - internal-pdf://0136987520/Oliveira Filho-2021-Oral preanesthetic medicat.pdf
PY  - 2021
SP  - 16
T2  - Brazilian Journal of Anesthesiology
TI  - Oral preanesthetic medication in children - comparison between midazolam alone and in combination with ketamine: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34411631
VL  - 16
ER  -
TY  - JOUR
AB  - **Objective**
To evaluate the effectiveness and safety of pharmacological interventions for the treatment of psychological distress in people with asthma. 

**Data sources**
Electronic searches were performed in Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, PubMed/Medline, Embase, PsycInfo, Health Technology Assessment Database and Web of Science (inception to April 2019). 

**Study selections**
Included studies were randomized controlled trials (RCT) or controlled clinical trials investigating the effect of pharmacological interventions for psychological distress in people with asthma. Records were screened and data extracted by two independent authors into standardized pilot-tested extraction templates. Data was analyzed according to standard Cochrane methodology and entered into Review Manager Software version 5.3.
AN  - 32065543
AU  - Tran,
AU  - L.
AU  - Sharrad,
AU  - K.
AU  - Kopsaftis,
AU  - Z.
AU  - Stallman,
AU  - H.
AU  - M.
AU  - Tai,
AU  - A.
AU  - Spurrier,
AU  - N.
AU  - Esterman,
AU  - A.
AU  - Carson-Chahhoud,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/02770903.2020.1731826
L1  - internal-pdf://3275728871/Tran-2021-Pharmacological interventions for th.pdf
PY  - 2021
SP  - 759-769
T2  - Journal of Asthma
TI  - Pharmacological interventions for the treatment of psychological distress in patients with asthma: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=32065543
UR  - https://www.tandfonline.com/doi/full/10.1080/02770903.2020.1731826
VL  - 58
ER  -
TY  - JOUR
AB  - The purpose of this study was to conduct an analysis of the effects of behavioral interventions used in alternative school settings on student outcomes, including group design (GD) and single-case design (SCD) studies. 

Behavioral interventions were broadly defined as interventions targeting behavior or thoughts and feelings, but not academics. An alternative school setting is defined as, &quot;A public elementary/secondary school that (1) addresses needs of students that typically cannot be met in a regular school, (2) provides nontraditional education, (3) serves as an adjunct to a regular school, or (4) falls outside the categories of regular, special education, or vocational education&quot; (National Center for Education Statistics, 2017). 

Studies meeting What Works Clearinghouse design standards for GD and SCD were included. A total of 21 eligible studies (13 GD; 8 SCD) were included across peer-reviewed journal articles and dissertations. The GD studies included a total of 1202 participants and SCD included 105 participants. Hedges&#039; g effect sizes measures were calculated separately for GD and SCD studies. Results indicate interventions in alternative settings have at least moderate effects on behavioral and emotional outcomes; these effects were higher for SCD studies. 

There were no significant moderators for GD studies, but outcomes were moderated by grade and race for SCD studies. The need for future studies with increased methodological rigor is discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-83084-001
AU  - Aspiranti,
AU  - K.
AU  - Mayworm,
AU  - A.
AU  - Gadke,
AU  - D.
AU  - L.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/pits.22591
L1  - internal-pdf://0806294758/Aspiranti-2021-Analysis of behavioral interven.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Psychology in the Schools
TI  - Analysis of behavioral interventions in alternative school settings
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-83084-001
UR  - https://onlinelibrary.wiley.com/doi/10.1002/pits.22591
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pits.22591?download=true
ER  -
TY  - JOUR
AB  - **Background**
Tourette syndrome (TS) is a neurodevelopmental disorder characterised by involuntary muscle movements manifesting as motor and vocal tics. In the majority, tics are manageable without medication. Where tics cause discomfort or impair function, behavioural or pharmaceutical treatments may be considered. 

**Aim(s)**
To provide a meticulous examination of the quality of evidence for the current pharmacological treatments for TS. 

**Method(s)**
PubMed and Google Scholar were searched to identify randomised, placebo-controlled trials (RCTs) of aripiprazole, risperidone, clonidine, guanfacine, haloperidol, pimozide, tiapride and sulpiride for the treatment of tics in children and adults with TS. Quality of reporting and risk of bias were assessed against the CONSORT checklist and Cochrane risk of bias criteria, respectively. 

**Result(s)**
Seventeen RCTs were identified. Response rates reached 88.6% for aripiprazole, 68.9% for clonidine, 62.5% for risperidone and 19% for guanfacine. Statistically significant improvements were reported for all medications compared to placebo in at least one study and for at least one measure of tic severity. Most studies predated the CONSORT and Cochrane criteria and did not score highly when assessed on these measures. 

**Conclusion(s)**
There are relatively few placebo-controlled trials of commonly prescribed medications. Studies are often of poor quality and short duration. There is evidence for the efficacy of each medication, but no drug is clearly superior. Clonidine and guanfacine are better tolerated than antipsychotics, but less effective. There is too little evidence to determine whether adults respond differently from children. Copyright &copy; The Author(s) 2021.
AN  - 2013241495
AU  - Besag,
AU  - F.
AU  - M.
AU  - C.
AU  - Vasey,
AU  - M.
AU  - J.
AU  - Lao,
AU  - K.
AU  - S.
AU  - J.
AU  - Chowdhury,
AU  - U.
AU  - Stern,
AU  - J.
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/02698811211032445
L1  - internal-pdf://0956505302/Besag-2021-Pharmacological treatment for Toure.pdf
PY  - 2021
SP  - 1037-1061
T2  - Journal of Psychopharmacology
TI  - Pharmacological treatment for Tourette syndrome in children and adults: What is the quality of the evidence? A systematic review
UR  - http://www.sagepub.co.uk/journal.aspx?pid=105678
UR  - https://journals.sagepub.com/doi/10.1177/02698811211032445
UR  - https://journals.sagepub.com/doi/pdf/10.1177/02698811211032445
VL  - 35(9)
ER  -
TY  - JOUR
AB  - Emotion dysregulation is a transdiagnostic phenomenon in Eating Disorders (ED), and Dialectical Behaviour Therapy (DBT) (which was developed for reducing dysregulated emotions in personality disorders) has been employed in patients with ED. This systematic review and meta-analysis investigated whether the effect of DBT was stronger on emotion dysregulation, general psychopathology, and Body Mass Index (BMI) in participants with ED, when compared to a control group (active therapy and waitlist). Eleven studies were identified in a systematic search in accordance with PRISMA guidelines. Most studies included participants with Binge Eating Disorder (BED) (n = 8), some with Bulimia Nervosa (BN) (n = 3), and only one with Anorexia Nervosa (AN). The pooled effect of DBT indicated a greater improvement in Emotion Regulation (ER) (g = -0.69, p = 0.01), depressive symptoms (g = -0.33, p &lt; 0.00001), ED psychopathology (MD = -0.90, p = 0.005), Objective Binge Episodes (OBE) (MD = -0.27, p = 0.003), and BMI (MD = -1.93, p = 0.01) compared to the control group. No improvement was detected in eating ER following DBT (p = 0.41). DBT demonstrated greater efficacy compared with the control group in improving emotion dysregulation, ED psychopathology, and BMI in ED. The limitations included the small number of studies and high variability.
AN  - WOS:000699580500001
AU  - Rozakou-Soumalia,
AU  - N.
AU  - Darvariu,
AU  - S.
AU  - Sjogren,
AU  - J.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/jpm11090931
L1  - internal-pdf://1565696602/Rozakou-Soumali-2021-Dialectical Behaviour The.pdf
PY  - 2021
SP  - 20
T2  - Journal of Personalized Medicine
TI  - Dialectical Behaviour Therapy Improves Emotion Dysregulation Mainly in Binge Eating Disorder and Bulimia Nervosa: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000699580500001
UR  - https://mdpi-res.com/d_attachment/jpm/jpm-11-00931/article_deploy/jpm-11-00931-v4.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Background** Much is not known about the efficacy of interventions to prevent poor mental health outcomes in young people by targeting either the general population (universal prevention) or asymptomatic individuals with high risk of developing a mental disorder (selective prevention). 

**Methods** We conducted a PRISMA/MOOSE-compliant systematic review and meta-analysis of Web of Science to identify studies comparing post-test efficacy (effect size [ES]; Hedges&#039; g) of universal or selective interventions for poor mental health outcomes versus control groups, in samples with mean age &lt;35 years (PROSPERO: CRD42018102143). Measurements included random-effects models, I-2 statistics, publication bias, meta-regression, sensitivity analyses, quality assessments, number needed to treat, and population impact number. 

**Results** 295 articles (447,206 individuals; mean age = 15.4) appraising 17 poor mental health outcomes were included. Compared to control conditions, universal and selective interventions improved (in descending magnitude order) interpersonal violence, general psychological distress, alcohol use, anxiety features, affective symptoms, other emotional and behavioral problems, consequences of alcohol use, posttraumatic stress disorder features, conduct problems, tobacco use, externalizing behaviors, attention-deficit/hyperactivity disorder features, and cannabis use, but not eating-related problems, impaired functioning, internalizing behavior, or sleep-related problems. Psychoeducation had the highest effect size for ADHD features, affective symptoms, and interpersonal violence. Psychotherapy had the highest effect size for anxiety features. 

**Conclusion:: Universal and selective preventive interventions for young individuals are feasible and can improve poor mental health outcomes.
AN  - WOS:000652457600003
AU  - de
AU  - Pablo,
AU  - G.
AU  - S.
AU  - De
AU  - Micheli,
AU  - A.
AU  - Solmi,
AU  - M.
AU  - Oliver,
AU  - D.
AU  - Catalan,
AU  - A.
AU  - Verdino,
AU  - V.
AU  - Di
AU  - Maggio,
AU  - L.
AU  - Bonoldi,
AU  - I.
AU  - Radua,
AU  - J.
AU  - Boy,
AU  - O.
AU  - B.
AU  - Provenzani,
AU  - U.
AU  - Ruzzi,
AU  - F.
AU  - Calorio,
AU  - F.
AU  - Nosari,
AU  - G.
AU  - Di
AU  - Marco,
AU  - B.
AU  - Famularo,
AU  - I.
AU  - Montealegre,
AU  - I.
AU  - Signorini,
AU  - L.
AU  - Molteni,
AU  - S.
AU  - Filosi,
AU  - E.
AU  - Mensi,
AU  - M.
AU  - Balottin,
AU  - U.
AU  - Politi,
AU  - P.
AU  - Shin,
AU  - J.
AU  - I.
AU  - Correll,
AU  - C.
AU  - U.
AU  - Arango,
AU  - C.
AU  - Fusar-Poli,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/hrp.0000000000000294
L1  - internal-pdf://1330871513/de Pablo-2021-Universal and Selective Interven.pdf
PY  - 2021
SP  - 196-215
T2  - Harvard Review of Psychiatry
TI  - Universal and Selective Interventions to Prevent Poor Mental Health Outcomes in Young People: Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000652457600003
VL  - 29
ER  -
TY  - JOUR
AB  - **OBJECTIVES**: Acceptance and commitment therapy (ACT) has accrued a growing evidence-base for a wide variety of psychological difficulties. Given that ACT promotes broad and flexible repertoires of behaviour as well as neutralizing the ubiquitous psychological processes theorized to be responsible for much human suffering, such an approach may hold promise. The use of ACT-informed parenting interventions offers another alternative to solely behavioural approaches but it remains relatively understudied and in need of further exploration.

**DESIGN**: The current systematic review, which searched four databases, aimed to collate all ACT interventions that included parental therapeutic components in the treatment of various child presenting difficulties. The review also rated the methodological rigour of the ACT evidence-base for this type of treatment format.

**RESULTS**: Twenty-seven individual studies covering a broad spectrum of presenting problems were included, comprising of 1,155 participants. A large proportion of studies were within-group designs with a smaller number using randomized controlled trials. The majority of studies reported improvements on either parent report symptoms regarding child physical or psychological functioning as well as parent-reported measures of stress, depression, and anxiety. Similar improvements were noted on a number of ACT mechanisms of change outcomes, including mindfulness, acceptance, and cognitive fusing. These gains were evident for parents of children with neurodevelopmental disorders, chronic pain, and significant physical health difficulties. Maintenance or further treatment gains were often reported at follow-up. These positive findings are tempered by low levels of methodological rigour common in some of the studies included.

**CONCLUSIONS**: Despite these limitations, ACT holds promise as a transdiagnostic intervention that can help with the parenting of children with a range of psychological and physical difficulties.PRACTITIONER POINTS: ACT has accrued a relatively strong evidence base for a range of psychological difficulties. Despite some methodological shortcomings, ACT shows promise as an intervention to help parents manage stress and difficulties especially in relation to children with autism, chronic pain, and physical health needs. Further research is required in comparing ACT to more established treatments and helping consolidate initial positive findings.
AD  - Byrne, Gary. Health Service Executive, Dublin, Ireland.Ghrada, Aine Ni. Health Service Executive, Dublin, Ireland.O&#039;Mahony, Teresa. Health Service Executive, Dublin, Ireland.Brennan, Emma. School of Psychology, Trinity College, Dublin, Ireland.
AN  - 32406169
AU  - Byrne,
AU  - G.
AU  - Ghrada,
AU  - A.
AU  - N.
AU  - O&#039;Mahony,
AU  - T.
AU  - Brennan,
AU  - E.
DA  - Apr
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/papt.12282
DP  - Ovid Technologies
J2  - Psychol Psychother
L1  - internal-pdf://1674132753/Byrne-2021.pdf
LA  - English
M3  - Review
N1  - Byrne, GaryGhrada, Aine NiO&#039;Mahony, TeresaBrennan, Emma
PY  - 2021
SP  - 378-407
T2  - Psychology &amp; Psychotherapy: Theory, Research &amp; Practice
TI  - A systematic review of the use of acceptance and commitment therapy in supporting parents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32406169
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32406169&amp;id=doi:10.1111%2Fpapt.12282&amp;issn=1476-0835&amp;isbn=&amp;volume=94&amp;issue=2&amp;spage=378&amp;pages=378-407&amp;date=2021&amp;title=Psychology+%26+Psychotherapy%3A+Theory%2C+Research+%26+Practice&amp;atitle=A+systematic+review+of+the+use+of+acceptance+and+commitment+therapy+in+supporting+parents.&amp;aulast=Byrne&amp;pid=%3Cauthor%3EByrne+G%3C%2Fauthor%3E%3CAN%3E32406169%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://bpspsychub.onlinelibrary.wiley.com/doi/10.1111/papt.12282
UR  - https://bpspsychub.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/papt.12282?download=true
VL  - 94 Suppl 2
ER  -
TY  - JOUR
AB  - **Objective**: Research evidence and clinical observation support the importance of family involvement in the treatment of childhood behavior problems, and strengths-based, solution-oriented treatment offers an alternative to a problem-focused treatment approach. The current study provides a systematic review of solution-focused brief therapy (SFBT) for behavior problems in children and adolescents, and conducts meta-analyses regarding the effectiveness of SFBT compared to control conditions, the moderating role of family involvement in SFBT, and the effects of SFBT for internalizing versus externalizing behaviors. 

**Methods**: SFBT studies from January 1, 1990 to February 21, 2019 were retrieved from major databases and included published and unpublished studies and dissertations. Twenty studies with control or comparison groups (9 randomized, 11 non-randomized) met all inclusion criteria and were analyzed using robust variance estimation (RVE). 

**Results**: The RVE meta-analysis found a small to medium positive effect size favoring SFBT over control conditions for child behavioral problems (g = 0.43, 95% CI [0.20, 0.67], p = .001). The study did not find evidence of a moderating effect from family involvement in SFBT interventions, and there was no statistically significant difference between the effect sizes of family-involved SFBT (g = 0.37, 95% CI [-0.46, 1.21]) and family non-involved SFBT (g = 0.61, 95% CI [-0.30, 1.52]) for child behavior problems. For externalizing behaviors, SFBT showed greater effectiveness than comparison groups with a small to medium effect size (g = 0.43, 95% CI [0.18, 0.68]), but the small effect size favoring SFBT for internalizing problems was not significant (g = 0.18, 95% CI [-0.01, 0.38]). 

**Conclusions**: The evidence supports the overall effectiveness of SFBT for addressing behavior problems in children and adolescents, with evidence of greater effectiveness for externalizing rather than internalizing behaviors. Findings indicated no significant effect of including a family-involvement component in solution-focused interventions for child behavior problems, suggesting the need for further research on moderating factors that may enhance the effectiveness of SFBT with children and families. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Hsu, Kai-Shyang: casehsu@scu.edu.tw; Eads, Ray: eads.34@osu.edu; Lee, Mo Yee: lee.355@osu.edu; Wen, Zhemin: wen.176@osu.eduHsu, Kai-Shyang: Soochow University, No. 70, Linhsi Road, Shihlin District, Taipei City, Taiwan, 111002, casehsu@scu.edu.twHsu, Kai-Shyang: Soochow University, Taipei City, TaiwanEads, Ray: Ohio State University, Columbus, OH, USLee, Mo Yee: Ohio State University, Columbus, OH, USWen, Zhemin: Shan Ai Zhao Yue Mental Counseling Center, Shenzhen, China
AN  - 2020-90546-001
AU  - Hsu,
AU  - K.-S.
AU  - Eads,
AU  - R.
AU  - Lee,
AU  - M.
AU  - Y.
AU  - Wen,
AU  - Z.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.childyouth.2020.105620
DP  - Ovid Technologies
KW  - Children and adolescents, Meta-analysis, Intervention effectiveness, Solution-focused brief therapy, Family involvement, Behavioral problems
KW  - *Behavior Problems
KW  - *Brief Psychotherapy
KW  - *Family
KW  - *Solution Focused Therapy
KW  - *Treatment Effectiveness Evaluation
KW  - Adolescent Development
KW  - Childhood Development
KW  - Externalization
KW  - Family Intervention
KW  - Psychotherapy &amp; Psychotherapeutic Counseling [3310]
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://0424090150/Hsu-2021.pdf
LA  - English
M3  - Meta Analysis
PY  - 2021
T2  - Children and Youth Services Review Vol 120 2021, ArtID 105620
TI  - Solution-focused brief therapy for behavior problems in children and adolescents: A meta-analysis of treatment effectiveness and family involvement
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-90546-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2020.105620&amp;issn=0190-7409&amp;isbn=&amp;volume=120&amp;issue=&amp;spage=105620&amp;pages=&amp;date=2021&amp;title=Children+and+Youth+Services+Review&amp;atitle=Solution-focused+brief+therapy+for+behavior+problems+in+children+and+adolescents%3A+A+meta-analysis+of+treatment+effectiveness+and+family+involvement.&amp;aulast=Hsu&amp;pid=%3Cauthor%3EHsu%2C+Kai-Shyang%3C%2Fauthor%3E%3CAN%3E2020-90546-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 120
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Behavioral parent training is an evidence-based intervention for children with attention-deficit/hyperactivity disorder (ADHD), but it is unknown which of its components are most effective. This meta-regression analysis investigated which specific behavioral techniques that parents learn in parent training are associated with effects on parental outcomes. 

**METHOD**: A search was performed for randomized controlled trials on parent training for children with ADHD, with positive parenting, negative parenting, parenting sense of competence, parent-child relationship quality, and parental mental health as outcome measures. After screening 23,026 publications, 29 studies contributing 138 effect sizes were included (N = 2,345). For each study, the dosage of 39 behavioral techniques was derived from intervention manuals, and meta-regression determined which techniques were related to outcomes. 

**RESULTS**: Parent training had robust small- to medium-sized positive effects on all parental outcomes relative to control conditions, both for unblinded and probably blinded measures. A higher dosage of techniques focusing on the manipulation of antecedents of behavior was associated with better outcomes on parenting sense of competence and parental mental health, and a higher dosage of techniques focusing on reinforcement of desired behaviors was related to larger decreases in negative parenting. Higher dosages of psychoeducation were negatively related to parental outcomes. 

**CONCLUSION**: Although techniques were not investigated in isolation, the results suggested that manipulation of antecedents of behavior and reinforcement techniques are key components of parent training for children with ADHD in relation to parental outcomes. These exploratory findings may help to strengthen and tailor parent training interventions for children with ADHD.
AN  - 34224837
AU  - Dekkers,
AU  - T.
AU  - J.
AU  - Hornstra,
AU  - R.
AU  - van
AU  - der
AU  - Oord,
AU  - S.
AU  - Luman,
AU  - M.
AU  - Hoekstra,
AU  - P.
AU  - J.
AU  - Groenman,
AU  - A.
AU  - P.
AU  - van
AU  - den
AU  - Hoofdakker,
AU  - B.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2021.06.015
L1  - internal-pdf://1883405779/Dekkers-2021-Meta-analysis_ Which Components o.pdf
PY  - 2021
SP  - 02
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Meta-analysis: Which Components of Parent Training Work for Children With Attention-Deficit/Hyperactivity Disorder?
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34224837
UR  - https://www.jaacap.org/article/S0890-8567(21)00420-2/pdf
VL  - 02
ER  -
TY  - JOUR
AB  - **Objective**
The efficacy of antidepressant drugs combined with psychotherapy is controversial; hence, this meta-analysis was conducted to assess the efficacy of the combination therapy. 

**Methods**
Relevant literature was searched in PubMed, Web of Science and Embase, Chinese databases CNKI, and WanFang Data. We included the literature on the comparison of the sertraline combined with cognitive behavioral therapy (CBT) and each treatment alone for adolescent depression published in 2000-2021. Meta-analysis was performed using Stata16.0 software. 

**Results**
A total of 421 relevant articles were retrieved, and 14 studies were finally included. In comparison with the control group (sertraline), sertraline combined with CBT achieved higher response rate (OR=5.07, 95% CI: 3.00, 8.58) and lower incidence of adverse reactions (OR=0.43, 95% CI: 0.24, 0.75). Before treatment, there were no significant differences in depression score, anxiety score, and symptom self-rating scale score between the two groups. After treatment, depression score (SMD=-2.79, 95% CI: -3.64, -1.94), anxiety score (SMD=-1.22, 95% CI: -1.96, -0.47), and symptom self-rating scale score (SMD=-1.73, 95% CI: -3.19, -0.27) were significantly lower in the combined treatment group than in the control group. 

**Conclusion**
Although the number of comparative trials is small, this study shows that sertraline is effective for adolescent depression, but sertraline combined with CBT is more effective. The latter can significantly reduce the incidence of depressive symptoms, anxiety, and adverse reactions in patients. Therefore, this combination therapy is recommended for the clinical treatment of adolescent depression. Copyright &copy; 2021 Wenliang Liu et al.
AN  - 2016491407
AU  - Liu,
AU  - W.
AU  - Li,
AU  - G.
AU  - Wang,
AU  - C.
AU  - Wang,
AU  - X.
AU  - Yang,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1155/2021/5309588
L1  - internal-pdf://1120247592/Efficacy of Sertraline Combined with Cogn-2021.pdf
PY  - 2021
T2  - Computational and Mathematical Methods in Medicine
TI  - Efficacy of Sertraline Combined with Cognitive Behavioral Therapy for Adolescent Depression: A Systematic Review and Meta-Analysis
UR  - http://www.hindawi.com/journals/cmmm/
UR  - https://downloads.hindawi.com/journals/cmmm/2021/5309588.pdf
VL  - 2021 (no pagination)
ER  -
TY  - JOUR
AB  - <b>Objective:</b> To assess the effectiveness of physical activity (PA) intervention on attention-deficit/hyperactivity disorder (ADHD)-related symptoms.

**Method**: Studies that investigated PA intervention for ADHD-related symptoms were identified through searching PubMed, Web of Science, Cochrane Library, and Embase databases from inception through June 2021. Standardized mean difference (SMD) with 95% confidence interval (CI) was used to assess the effectiveness of PA intervention on improving ADHD-related symptoms. The meta-analyses were conducted using fixed-effect or random-effect models according to the heterogeneity of the studies.

**Results**: Nine before&ndash;after studies (232 participants) and 14 two-group control studies (162 participants/141 controls) were included in this meta-analysis. Combined results for before&ndash;after studies indicated significant improvements on all studied ADHD-related symptoms (inattention: SMD = 0.604, 95% CI: 0.374&ndash;0.834, p &lt; 0.001; hyperactivity/impulsivity: SMD = 0.676, 95% CI: 0.401&ndash;0.950, p &lt; 0.001; emotional problems: SMD = 0.416, 95% CI: 0.283&ndash;0.549, p &lt; 0.001; behavioral problems: SMD = 0.347, 95% CI: 0.202&ndash;0.492, p &lt; 0.001). Meta-analyses for two-group control studies further confirmed that PA intervention significantly improved the inattentive symptom (SMD = 0.715, 95% CI: 0.105, 1.325, p = 0.022). Subgroup analyses suggested significant beneficial effect on inattention symptoms in children. Moreover, closed motor skills were beneficial for hyperactive/impulsive problems (SMD = 0.671, p &lt; 0.001), while open motor skills were beneficial for attention problems (SMD = 0.455, p = 0.049). When excluding studies with combined medication, the studies in unmedicated participants in before&ndash;after studies still showed significant results in all studied ADHD-related symptoms as in the overall analysis. Given the limited sample size, the best frequency and intensity of PA intervention need further investigation.

**Conclusion**: Our results suggested that PA intervention could possibly improve ADHD-related symptoms, especially inattention symptoms. Closed-skill and open-skill activities could be beneficial for hyperactivity/impulsivity and inattention symptoms, respectively. Further high-quality randomized clinical trials with large sample size are needed.
AN  - 34764893
AU  - Xie,
AU  - Y.
AU  - Gao,
AU  - X.
AU  - Song,
AU  - Y.
AU  - Zhu,
AU  - X.
AU  - Chen,
AU  - M.
AU  - Yang,
AU  - L.
AU  - Ren,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2021.706625
L1  - internal-pdf://2981282744/Xie-2021.pdf
PY  - 2021
SP  - 706625
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Effectiveness of Physical Activity Intervention on ADHD Symptoms: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34764893
VL  - 12
ER  -
TY  - JOUR
AB  - Adverse childhood experiences (ACEs) are associated with various mental health problems such as depression, anxiety, drug abuse, and suicide-related behaviors. Yet, it is largely unknown if non-pharmacological interventions are beneficial in improving mental health among ACEs survivors. The purposes of the current meta-analysis were to: (1) evaluate the efficacy of non-pharmacological interventions in reducing depressive symptom severity among those exposed to ACEs, and, (2) estimate the pooled effect size of these interventions. We searched PubMed, CINAHL, and PsycINFO for randomized controlled trials of psychological interventions for depression among ACEs survivors. Two reviewers independently extracted article data and evaluated the quality of studies using the Cochrane risk-of-bias criteria. We estimated the pooled effect sizes using a random-effects model. We also performed sensitivity tests using a meta-regression and sub-group analyses. Using the pooled data of 1624 individuals from 20 unique RCTs, we found that non-pharmacological intervention had a medium to large effect size in reducing depressive symptom severity compared to control conditions (Hedges&#039; g=0.714, 95% CI [0.46, 0.97]). Such efficacy was sustained over the shorter-term follow-up (0 to 6 months; Hedges&#039; g=0.23, 95% CI [0.04, 0.49]). Although there was an indication that the efficacy may be sustained in the longer term (12 months or more; Hedges&#039; g=0.53, 95% CI: [-0.17, 1.22]), this finding was not statistically significant. Cognitive approaches had a larger effect size than noncognitive interventions. In conclusion, non-pharmacological interventions are efficacious options for treating depression among individuals with a history of adverse childhood experiences. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-11206-008
AU  - Elrefaay,
AU  - S.
AU  - M.
AU  - Wang,
AU  - S.
AU  - Park,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jbct.2021.05.001
L1  - internal-pdf://0663615302/Elrefaay_2021.pdf
PY  - 2021
SP  - 349-362
T2  - Journal of Behavioral and Cognitive Therapy
TI  - Non-pharmacological interventions for depression among survivors of adverse childhood experiences: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-11206-008
VL  - 31
ER  -
TY  - JOUR
AB  - **Objectives**
While mindfulness-based parenting programs (MPPs) are increasingly popular for reducing child behavior problems, the evidence for the advantages of MPP over existing behavioral parent training is unclear. Existing systematic reviews have largely excluded the breadth of MPP protocols, including those that integrate behavioral skills components. Therefore, a scoping review was conducted to map the nature and extent of research on MPPs for parents of children aged 3 to 12 years with behavioral problems. 

**Methods**
PRISMA-ScR guidelines were used to conduct an encompassing peer literature review of cross-disciplinary databases. Studies were included if they reported mindfulness interventions for parents of children aged between 3 and 12 years with externalizing behavior problems and had an outcome measure of child behavioral problems that could be represented as an effect size. Randomized controlled trials as well as quasi-experimental, pre-post studies and unpublished dissertations were included. 

**Results**
Sixteen studies met the inclusion criteria (N = 1362). The majority of MPPs delivered mindfulness adapted to parenting based on the Bogels&#039; protocol within clinical settings. There was a dearth of fully integrated mindfulness and behavioral programs. MPPs generally produced pre-to-post-intervention improvements with small effect sizes across child behavior and parent style, stress, and mindfulness measures. Examining longer follow-up periods compared to pre-intervention, effects reached a moderate size across most outcome measures. 

**Conclusions**
MPPs continue to show promise in improving child behavior and parental mindfulness, well-being, and style. Further research is needed to determine how to best leverage the advantages of mindfulness in augmenting the well-established effectiveness of behavioral programs.
AN  - WOS:000740198100001
AU  - Donovan,
AU  - M.
AU  - O.
AU  - Pickard,
AU  - J.
AU  - A.
AU  - Herbert,
AU  - J.
AU  - S.
AU  - Barkus,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12671-021-01799-y
L1  - internal-pdf://2017236402/Mindful Parent Training for Parents of Childre.pdf
PY  - 2021
SP  - 20
T2  - Mindfulness
TI  - Mindful Parent Training for Parents of Children Aged 3-12 Years with Behavioral Problems: a Scoping Review
UR  - &lt;Go to ISI&gt;://WOS:000740198100001
UR  - https://link.springer.com/content/pdf/10.1007/s12671-021-01799-y.pdf
ER  -
TY  - JOUR
AB  - Even compared with students with other disabilities, students with autism spectrum disorder (ASD) often experience poor postsecondary employment outcomes. Video-based intervention (VBI) has been effective in teaching a variety of skills to students with ASD, but there has yet to be a quantitative synthesis evaluating its effectiveness to teach vocational skills specifically. Therefore, the aim of this synthesis was to empirically evaluate the effectiveness of VBI to teach vocational skills to transition-age youth with ASD. This review analyzed 22 studies using design standards, quality indicators, visual analysis, success estimates, and Tau-U effect sizes. The findings indicate that VBI is effective in teaching employable skills to this population, but further diversification of skills, student demographics, and authentic implementation contexts is needed.
AN  - WOS:000677936600001
AU  - Chen,
AU  - B.
AU  - B.
AU  - Yakubova,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40489-021-00282-7
L1  - internal-pdf://0777285749/Chen-Evaluating the Effects of Video-Based Int.pdf
PY  - 2021
SP  - 16
T2  - Review Journal of Autism and Developmental Disorders
TI  - Evaluating the Effects of Video-Based Intervention to Teach Vocational Skills to Transition-Age Youth with Autism Spectrum Disorder: an Evidence-Based Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000677936600001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-021-00282-7.pdf
ER  -
TY  - JOUR
AB  - A student&#039;s sense of school belonging is critical to school success, yet internationally, a large proportion of secondary students do not feel that they belong to their school. However, little is understood about how schools can address this issue, nor what evidence-based interventions are available to increase belonging among secondary school students. 

The aim of this study is to identify and critically review the evidence on school-based interventions that increase a sense of school belonging in adolescents. Seven electronic databases and the Cochrane Central Register of Controlled Trials were searched from 1999 to February 2021 using &#039;school belonging&#039; and &#039;intervention&#039; amongst the key search terms. 

A total of 22 controlled trials were identified with 14 studies reporting effective school-based interventions for enhancing a sense of adolescent school belonging. Successful interventions targeted students&#039; strengths and promoted positive interactions between students and between school staff and students. 

Overall, this review found a paucity of interventions that intentionally aimed to develop adolescent school belonging. Inconsistencies in terminology use and definitions describing school belonging were identified even when similar measurement tools were utilised. Findings of this review have important practice implications and provide information to support schools to select evidence-based interventions to improve students&#039; sense of school belonging.
AN  - WOS:000667913000001
AU  - Allen,
AU  - K.
AU  - A.
AU  - Jamshidi,
AU  - N.
AU  - Berger,
AU  - E.
AU  - Reupert,
AU  - A.
AU  - Wurf,
AU  - G.
AU  - May,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10648-021-09621-w
L1  - internal-pdf://1744521307/Allen-Impact of School-Based Interventions for.pdf
PY  - 2021
SP  - 29
T2  - Educational Psychology Review
TI  - Impact of School-Based Interventions for Building School Belonging in Adolescence: a Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000667913000001
UR  - https://link.springer.com/content/pdf/10.1007/s10648-021-09621-w.pdf
ER  -
TY  - JOUR
AB  - An abstract is not available for this content
AN  - 34779375
AU  - Bergsund,
AU  - H.
AU  - B.
AU  - Drozd,
AU  - F.
AU  - Olafsen,
AU  - K.
AU  - S.
AU  - Nilsen,
AU  - K.
AU  - H.
AU  - Linnerud,
AU  - S.
AU  - Kjobli,
AU  - J.
AU  - Jacobsen,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1017/S0954579421001164
L1  - internal-pdf://1927912600/The effect of relationship-based interven-2021.pdf
PY  - 2021
SP  - 1-20
T2  - Development &amp; Psychopathology
TI  - The effect of relationship-based interventions for maltreated children and adolescents: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34779375
UR  - https://www.cambridge.org/core/journals/development-and-psychopathology/article/abs/effect-of-relationshipbased-interventions-for-maltreated-children-and-adolescents-a-systematic-review-and-metaanalysis/730515244F232316DB1ADC874A4FC968
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Subthreshold depression has been found to be associated with considerable impairment and an increased risk of developing major depression. Although several randomized trials have examined the effects of psychological interventions for subthreshold depression in children and adolescents, no meta-analysis has integrated the results of these trials.

**METHOD**: We searched 4 bibliographic databases and included randomized trials comparing psychological interventions with control conditions in children and adolescents scoring above a cut-off of a depression questionnaire but not meeting diagnostic criteria for major depression (or persistent depressive disorder) according to a diagnostic interview. Effect sizes and incidence rates of major depression were pooled with random effects meta-analyses.

**RESULTS**: A total of 12 trials with 1,576 children and adolescents met inclusion criteria. The overall effect size indicating the difference between treatment and control at post-test was g = 0.38 (95% CI = 0.14-0.63), which corresponds to a number-needed-to-treat (NNT) of 8.4. Heterogeneity was moderate to high (I&lt;sup&gt;2&lt;/sup&gt; = 61; 95% CI = 28-79), and there was significant risk of publication bias (p &lt; .04). The 2 studies in children less than 12 years of age showed nonsignificant effects (g = 0.01; 95% CI = -1.16 to 1.18). We found no significant effect on the incidence of major depression at follow-up (relative risk = 0.52; 95% CI = 0.25-1.08), although this may be related to low statistical power.

**CONCLUSION**: Interventions for subthreshold depression may have positive acute effects in adolescents. There is currently insufficient evidence, however, that these interventions are effective in children less than 12 years of age, or that they prevent the onset of major depression at follow-up.
AD  - Cuijpers, Pim. Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, The Netherlands. Electronic address: p.cuijpers@vu.nl.Pineda, Blanca S. Institute for International Internet Interventions for Health (i4Health), Palo Alto University, California.Ng, Mei Yi. Florida International University, Miami.Weisz, John R. Harvard University, Cambridge, Massachusetts.Munoz, Ricardo F. Institute for International Internet Interventions for Health (i4Health), Palo Alto University, California.Gentili, Claudio. University of Padova, Italy.Quero, Soledad. Universitat Jaume I, Castellon, Spain, and CIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), Madrid, Spain.Karyotaki, Eirini. Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, The Netherlands.
AN  - 33596437
AU  - Cuijpers,
AU  - P.
AU  - Pineda,
AU  - B.
AU  - S.
AU  - Ng,
AU  - M.
AU  - Y.
AU  - Weisz,
AU  - J.
AU  - R.
AU  - Munoz,
AU  - R.
AU  - F.
AU  - Gentili,
AU  - C.
AU  - Quero,
AU  - S.
AU  - Karyotaki,
AU  - E.
DA  - Feb 14
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2020.11.024
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
L1  - internal-pdf://2025407720/Cuijpers-2021.pdf
LA  - English
N1  - Using Smart Source ParsingFebCuijpers, PimPineda, Blanca SNg, Mei YiWeisz, John RMunoz, Ricardo FGentili, ClaudioQuero, SoledadKaryotaki, EiriniS0890-8567(21)00074-5
PY  - 2021
SP  - 14
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - A Meta-analytic Review: Psychological Treatment of Subthreshold Depression in Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33596437
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33596437&amp;id=doi:10.1016%2Fj.jaac.2020.11.024&amp;issn=0890-8567&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=A+Meta-analytic+Review%3A+Psychological+Treatment+of+Subthreshold+Depression+in+Children+and+Adolescents.&amp;aulast=Cuijpers&amp;pid=%3Cauthor%3ECuijpers+P%3C%2Fauthor%3E%3CAN%3E33596437%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.jaacap.org/article/S0890-8567(21)00074-5/pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Behavioral Parent Training (BPT) traditionally occurs in face-to-face (FTF BPT). Recently, Behavioral Intervention Technology (BIT) has been developed to deliver BPT in lieu of or as an adjunct to FTF BPT using websites, computer software, smartphone applications, podcasts, pre-recorded sessions, and teletherapy. 

The present meta-analysis reviews BIT BPT randomized control and comparison studies to determine the overall efficacy of BITs, if the level of human support significantly effects BIT BPT treatment outcomes, and which populations BIT BPT are effective for, by analyzing the following study variables: socioeconomic status, race, and clinical population. 

The analyses indicated that, overall, BIT BPT is an effective treatment (g = 0.62), and did not indicate a significant difference between levels of human support (chi(2) (3) = 4.94, p = 0.18). Analysis did indicate a significant difference between studies that used waitlist or education control groups, compared to studies that used active treatment controls (chi(2) (1) = 12.90, p = 0.00). The analyses did not indicate a significant difference between clinical population, low socioeconomic status, and racial minority studies. These findings provide preliminary evidence that BIT BPT is effective for treating child and adolescent externalizing behavior in a variety of populations.</p>
AN  - WOS:000717004500001
AU  - Bausback,
AU  - K.
AU  - B.
AU  - Bunge,
AU  - E.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/socsci10100367
L1  - internal-pdf://0726273412/socsci-10-00367-v2.cleaned.pdf
PY  - 2021
SP  - 27
T2  - Social Sciences-Basel
TI  - Meta-Analysis of Parent Training Programs Utilizing Behavior Intervention Technologies
UR  - &lt;Go to ISI&gt;://WOS:000717004500001
VL  - 10
ER  -
TY  - JOUR
AB  - **ABSTRACT** Young people in residential out-of-home care often exhibit health and psychosocial challenges, which can emerge from childhood trauma. A body of research has examined the wellbeing of these young people; however, the ways in which interventions and practice models can improve the health and psychosocial wellbeing of young people in out-of-home care remains unclear. 

A systematic review was conducted to examine the effectiveness of interventions and practice models for improving health and psychosocial outcomes of young people in residential care and to identify relevant knowledge gaps. After a worldwide search, only four studies, from Australia (n = 2), USA (n = 1), and Canada (n = 1) were found. These studies evaluated Cognitive Behaviour Treatment, Healthy Eating Active Living, Power Through Choices and the Alternate Care Clinic. These studies aimed to improve numerous health and psychosocial outcomes including mental health, behaviour, obesity, pregnancy and sex. Despite limited evidence, the review suggests that contemporary interventions and practice models do have the potential to have positive impacts on the health and psychosocial outcomes of young people in residential care. Rigorous assessment of promising evidence-based interventions is urgently needed to advance best practice and improve outcomes. 

**IMPLICATIONS** Therapeutic and psychosocial approaches have significant impacts on the health and psychosocial wellbeing of young people in residential out-of-home care. Interventions and practice models within residential out-of-home care should incorporate trauma-informed care and psychoeducation. Findings from this review may guide the design and implementation of interventions and practice models in out-of-home care as well highlighting knowledge gaps for future research in this field. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Skouteris, Helen: helen.skouteris@monash.eduSkouteris, Helen, helen.skouteris@monash.edu
AN  - 2021-36617-001
AU  - Galvin,
AU  - E.
AU  - O&#039;Donnell,
AU  - R.
AU  - Breman,
AU  - R.
AU  - Avery,
AU  - J.
AU  - Mousa,
AU  - A.Halfpenny,
AU  - N.
AU  - Skouteris,
AU  - H.
DA  - Apr
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/0312407X.2020.1856394
DP  - Ovid Technologies
KW  - Out-of-home Care, Residential Care, Health, Psychosocial Health, Interventions, Implementation
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
L1  - internal-pdf://3577034689/Galvin-2021.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Australian Social Work
TI  - Interventions and practice models for improving health and psychosocial outcomes for children in residential out-of-home care: Systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-36617-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F0312407X.2020.1856394&amp;issn=0312-407X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=No&amp;pages=No+Pagination+Specified&amp;date=2021&amp;title=Australian+Social+Work&amp;atitle=Interventions+and+practice+models+for+improving+health+and+psychosocial+outcomes+for+children+in+residential+out-of-home+care%3A+Systematic+review.&amp;aulast=Galvin&amp;pid=%3Cauthor%3EGalvin%2C+Emma%3C%2Fauthor%3E%3CAN%3E2021-36617-001%3C%2FAN%3E%3CDT%3E%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/full/10.1080/0312407X.2020.1856394
UR  - https://www.tandfonline.com/doi/pdf/10.1080/0312407X.2020.1856394?needAccess=true
ER  -
TY  - JOUR
AB  - **Background**
Young people present high rates of cannabis use, abuse, and dependence. The United Nations estimates that roughly 3.8% of the global population aged 15-64 years used cannabis at least once in 2017. Cannabis use in young people may impair cognitive skills, interfere with learning, impact relationships, and lead to long term behavioural and psychological consequences. Online cannabis interventions (OCI) are increasingly popular, but their dissemination is not often supported by empirical evidence. 

**Aim**
To systematically compile and analyse the effectiveness of OCI for the reduction of cannabis use among adolescents and young adults (AYA). Methods Pooled effect sizes of cannabis use between treatment and control groups were estimated. For each comparison, Hedge&#039;s g was calculated using a random effects model. 

**Results** 
The search strategy yielded 4531 articles. Of those, a total of 411 articles were retrieved for detailed evaluation resulting in 17 eligible studies (n = 3525). Analyses revealed that online interventions did not significantly reduce cannabis consumption (Hedge&#039;s g = -0.061, 95% CI [-0.363] to [-0.242], p = .695) and high heterogeneity was noted (Q = 191.290). More recent studies using structured interventions, daily feedback, AYA centred designs, and peer support, specifically targeting CU seemed to have positive effects to address CU in this population. 

**Conclusions**
The lack of positive outcomes suggests that more specific and targeted interventions may be necessary to promote cannabis-related behavioural change among young people. These targeted interventions may include structured CU modules, daily feedback, peer support for increased adherence, user-centred design procedures, and input from key stakeholders such as families and service providers. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-81914-001
AU  - Beneria,
AU  - A.
AU  - Santesteban-Echarri,
AU  - O.
AU  - Daigre,
AU  - C.
AU  - Tremain,
AU  - H.
AU  - Ramos-Quiroga,
AU  - J.
AU  - A.
AU  - McGorry,
AU  - P.
AU  - D.
AU  - Alvarez-Jimenez,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/eip.13226
L1  - internal-pdf://2132417562/Beneria-2021-Online interventions for cannabis.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Early Intervention in Psychiatry
TI  - Online interventions for cannabis use among adolescents and young adults: Systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-81914-001
UR  - https://onlinelibrary.wiley.com/doi/10.1111/eip.13226
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/eip.13226?download=true
ER  -
TY  - JOUR
AB  - Tourette&#039;s syndrome (TS) is a complex neurodevelopmental disorder characterized by high comorbidity. Treatment with psychotherapy is highly recommended, however, there exists limited available evidence on the use and the optimal psychotherapeutic outcome is debatable.

We performed a systematic search on several bibliographic databases for randomized controlled trials (RCTs) reporting the use of psychotherapy treatment in TS patients, from inception to August 1st, 2020, and without language restrictions. Outcome measures were measured by the Yale global tic severity scale (YGTSS) to determine the efficacy of psychotherapy. Data were pooled as Standard mean difference (SMD) in the Bayesian analysis of the random effect model. 

A total of 17 RCTs with 9 treatments and 1042 participants were included from an initial 4901 records. The primary outcome including, Comprehensive behavioral intervention (CBIT) [SMD = -1.43, 95%Credible interval (CrI): -2.39, -0.44], Exposure with response prevention (ERP) [SMD = -1.37, 95%CrI: -2.62, -0.13], Habit reversal therapy (HRT) [SMD = -0.93, 95%CrI: 1.83, -0.05], and Behavior therapy (BT) [SMD = -0.85, 95%CrI: 1.51, -0.18], were found to be significantly lower in the TS group compared with the control group (including wait-list, treatment-as-usual or other named control group). 

Based on the Surface under the cumulative ranking curve (SUCRA), CBIT (SUCRA value = 86.97%, 95%CrI: 44%, 100%) was found to be a suitable psychotherapeutic treatment for TS patients. High-quality RCTs on psychotherapy are needed to perform for establishing the foundation of the generation of evidence-based guidelines. Copyright &copy; 2021
AN  - 2014435116
AU  - Liang,
AU  - J.
AU  - H.
AU  - Zhang,
AU  - S.
AU  - X.
AU  - Chen,
AU  - Y.
AU  - C.
AU  - Tan,
AU  - K.
AU  - Y.
AU  - Zhang,
AU  - J.
AU  - S.
AU  - Zhao,
AU  - Y.
AU  - Kakaer,
AU  - A.
AU  - Chen,
AU  - Y.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jpsychires.2021.07.051
L1  - internal-pdf://1567434815/1-s2.0-S0022395621004817-main.cleaned.pdf
PY  - 2021
SP  - 451-461
T2  - Journal of Psychiatric Research
TI  - Role of psychotherapy strategy for the management of patients with Tourette syndrome - A Bayesian network meta-analysis
UR  - https://www.elsevier.com/locate/jpsychires
VL  - 143
ER  -
TY  - JOUR
AB  - **Background** Bullying first emerged as an important topic of research in the 1980s in Norway (Olweus), and a recent meta‐analysis shows that these forms of aggression remain prevalent among young people globally (Modecki et al.). Prominent researchers in the field have defined bullying as any aggressive behavior that incorporates three key elements, namely: (1) an intention to harm, (2) repetitive in nature, and (3) a clear power imbalance between perpetrator and victim (Centers for Disease Control and Prevention; Farrington). There are many negative outcomes associated with bullying perpetration, such as: suicidal ideation (Holt et al.), weapon carrying (Valdebenito et al.), drug use (Ttofi et al.), and violence and offending in later life (Ttofi et al.). Bullying victimization too is associated with negative outcomes such as: suicidal ideation (Holt et al.), anxiety, low self‐esteem and loneliness (Hawker&amp; Boulton). Therefore, school bullying is an important target for effective intervention, and should be considered a matter of public health concern.

**Objectives** The objective of this review is to establish whether or not existing school‐based antibullying programs are effective in reducing school‐bullyng behaviors. This report also updates a previous meta‐analysis conducted by Farrington and Ttofi. This earlier review found that antibullying programs are effective in reducing bullying perpetration and victimization and a primary objective of the current report is to update the earlier analysis of 53 evaluations by conducting new searches for evaluations conducted and published since 2009.

**Search Methods** Systematic searches were conducted using Boolean combinations of the following keywords: bully*; victim*; bully‐victim; school; intervention; prevention; program*; evaluation; effect*; and anti‐bullying. Searches were conducted on several online databases including, Web of Science, PscyhINFO, EMBASE, EMBASE, DARE, ERIC, Google Scholar, and Scopus. Databases of unpublished reports, such as masters&#039; and doctoral theses (e.g., Proquest) were also searched.

**Selection Criteria** Results from systematic searches were screened thoroughly against the following inclusion criteria. To be included in this review, a study must have: (1) described an evaluation of a school‐based antibullying program implemented with school‐age participants; (2) utilized an operational definition of school‐bullying that coincides with existing definitions; (3) measured school‐bullying perpetration and/or victimization using quantitative measures, such as, self‐, peer‐, or teacher‐report questionnaires; and (4) used an experimental or quasi‐experimental design, with one group receiving the intervention and another not receiving the intervention.

**Data Collection and Analysis** Of the 19,877 search results, 474 were retained for further screening. The majority of these were excluded, and after multiple waves of screening, 100 evaluations were included in our meta‐analysis. A total of 103 independent effect sizes were estimated and each effect size was corrected for the impact of including clusters in evaluation designs. Included evaluations were conducted using both randomized (n&thinsp;=&thinsp;45; i.e., randomized controlled trials/RCTs) and nonrandomized (n&thinsp;=&thinsp;44; i.e., quasi‐experimental designs with before/after measures; BA/EC) methodologies. All of these studies included measures of bullying outcomes before and after implementation of an intervention. The remaining 14 effect sizes were estimated from evaluations that used age cohort designs. Two models of meta‐analysis are used to report results in our report. All mean effects computed are presented using both the multivariance adjustment model (MVA) and random effects model (RE). The MVA model assigns weights to primary studies in direct proportion to study level sampling error as with the fixed effects model but adjusts the meta‐analytic standard error and confidence intervals for study heterogeneity. The RE model incorporates between‐study heterogeneity into the formula for assigning weights to primary studies. The differences and strengths/limitations of both approaches are discussed in the context of the present data.ResultsOur meta‐analysis identified that bullying programs significantly reduce bullying perpetration (RE: odds ratio [OR]&thinsp;=&thinsp;1.309; 95% confidence interval [CI]: 1.24&ndash;1.38; z&thinsp;=&thinsp;9.88; p&thinsp;&lt;&thinsp;.001) and bullying victimization (RE: OR&thinsp;=&thinsp;1.244; 95% CI: 1.19&ndash;1.31; z&thinsp;=&thinsp;8.92; p&thinsp;&lt;&thinsp;.001), under a random effects model of meta‐analysis. Mean effects were similar across both models of meta‐analysis for bullying perpetration (i.e., MVA: OR&thinsp;=&thinsp;1,324; 95% CI: 1.27&ndash;1.38; z&thinsp;=&thinsp;13.4; p&thinsp;&lt;&thinsp;.001) and bullying victimization (i.e., MVA: OR&thinsp;=&thinsp;1.248; 95% CI: 1.21&ndash;1.29; z&thinsp;=&thinsp;12.06; p&thinsp;&lt;&thinsp;.001). Under both computational models, primary studies were more effective in reducing bullying perpetration than victimization overall. Effect sizes varied across studies, with significant heterogeneity between studies for both bullying perpetration (Q&thinsp;=&thinsp;323.392; df&thinsp;=&thinsp;85; p&thinsp;&lt;&thinsp;.001; I2&thinsp;=&thinsp;73.716) and bullying victimization (Q&thinsp;=&thinsp;387.255; df&thinsp;=&thinsp;87; p&thinsp;&lt;&thinsp;.001; I2&thinsp;=&thinsp;77.534) outcomes. Analyses suggest that publication bias is unlikely. Between‐study heterogeneity was expected, given the large number of studies included, and thus, the number of different programs, methods, measures and samples used.

**Authors&#039; Conclusions** We conclude that overall, school‐based antibullying programs are effective in reducing bullying perpetration and bullying victimization, although effect sizes are modest. The impact of evaluation methodology on effect size appears to be weak and does not adequately explain the significant heterogeneity between primary studies. Moreover, the issue of the under‐/over‐estimation of the true treatment effect by different experimental designs and use of self‐reported measures is reviewed. The potential explanations for this are discussed, along with recommendations for future primary evaluations. Avenues for future research are discussed, including the need further explain differences across programs by correlating individual effect sizes with varying program components and varying methodological elements available across these 100 evaluations. Initial findings in the variability of effect sizes across different methodological moderators provide some understanding on the issue of heterogeneity, but future analyses based on further moderator variables are needed.
AU  - Gaffney,
AU  - H.
AU  - Ttofi,
AU  - M.
AU  - M.
AU  - Farrington,
AU  - D.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - https://doi.org/10.1002/cl2.1143
L1  - internal-pdf://1571552477/Gaffney.pdf
PY  - 2021
T2  - Campbell Systematic Reviews
TI  - Effectiveness of school‐based programs to reduce bullying perpetration and victimization: An updated systematic review and meta‐analysis
ER  -
TY  - JOUR
AB  - The intensive use of the Internet and communication technologies among adolescents has increased addiction and/or their problematic use. The innovative and revolutionary development of this technology can have negative effects on the mental and physical health of its users, and it seems to have a greater impact on adolescents. 

As this is causing a public health problem, the objective of this study was to review the different intervention and prevention programs for this problem in adolescents. 

A total of 14 programs met the inclusion criteria. The analysis of the programs allows for the identification of effective intervention designs for prevention, and also for the treatment of the current problems derived from the use of the Internet and technological devices among adolescent users.
AN  - WOS:000734566400001
AU  - Canas,
AU  - E.
AU  - Estevez,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/electronics10232923
L1  - internal-pdf://1128240031/Intervention Programs for the Problematic-2021.pdf
PY  - 2021
SP  - 18
T2  - Electronics
TI  - Intervention Programs for the Problematic Use of the Internet and Technological Devices: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000734566400001
UR  - https://mdpi-res.com/d_attachment/electronics/electronics-10-02923/article_deploy/electronics-10-02923-v2.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - As 30% of individuals with autism spectrum disorder (ASD) demonstrate difficulties with vocal output, augmentative and alternative communication (AAC) intervention can provide a means for those persons to have the ability to communicate with others. To determine the most effective mode of AAC for individuals with ASD, practitioners must have access to current comparative research in order to make evidence-based decisions. 

This systematic review searched ERIC, Google Scholar, PsycINFO, and Science Direct databases for studies that compared AAC modes, including mobile technology based speech-generating devices, in intervention with individuals with ASD. The search yielded nine (n = 9) alternating treatment design single case studies including a total of 36 participants with ASD with a mean age of seven (range: 3-13). The included studies were compared to evaluate operants, evidence-based best practices, preferences, and participant performance across AAC modes. Visual and statistical analyses indicated most participants not only preferred using the SGD but had performed better when using such devices compared to picture exchange and manual sign.

Findings suggest that practitioners should consider using mobile technology based SGDs to promote verbal behavior from children with a diagnosis of ASD. Additionally, research evaluating verbal operants beyond the initial mand (request) and incorporating participants who are adolescents or adults is needed.
AN  - WOS:000687493200001
AU  - Lorah,
AU  - E.
AU  - R.
AU  - Holyfield,
AU  - C.
AU  - Miller,
AU  - J.
AU  - Griffen,
AU  - B.
AU  - Lindbloom,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10882-021-09803-y
L1  - internal-pdf://3054648084/Lorah-A Systematic Review of Research Comparin.pdf
PY  - 2021
SP  - 24
T2  - Journal of Developmental and Physical Disabilities
TI  - A Systematic Review of Research Comparing Mobile Technology Speech-Generating Devices to Other AAC Modes with Individuals with Autism Spectrum Disorder
UR  - &lt;Go to ISI&gt;://WOS:000687493200001
UR  - https://link.springer.com/content/pdf/10.1007/s10882-021-09803-y.pdf
ER  -
TY  - JOUR
AB  - **Background**: Despite the established evidence base of psychological interventions in treating PTSD in children and young people, concern that these trauma-focused treatments may &#039;retraumatise&#039; patients or exacerbate symptoms and cause dropout has been identified as a barrier to their implementation. Dropout from treatment is indicative of its relative acceptability in this population. 

**Objective**: Estimate the prevalence of dropout in children and young people receiving a psychological therapy for PTSD as part of a randomized controlled trial (RCT). 

**Methods**: A systematic search of the literature was conducted to identify RCTs of evidence-based treatment of PTSD in children and young people. Proportion meta-analyses estimated the prevalence of dropout. Odds ratios compared the relative likelihood of dropout between different treatments and controls. Subgroup analysis assessed the impact of potential moderating variables. 

**Results**: Forty RCTs were identified. Dropout from all treatment or active control arms was estimated to be 11.7%, 95% CI [9.0, 14.6]. Dropout from evidence-based treatment (TFCBTs and EMDR) was 11.2%, 95% CI [8.2, 14.6]. Dropout from non-trauma focused treatments or controls was 12.8%, 95% CI [7.6, 19.1]. There was no significant difference in the odds of dropout when comparing different modalities. Group rather than individual delivery, and lay versus professional delivery, were associated with less dropout. 

**Conclusions**: Evidence-based treatments for children and young people with PTSD do not result in higher prevalence of dropout than non-trauma focused treatment or waiting list conditions. Trauma-focused therapies appear to be well tolerated in children and young people.
AN  - 34377359
AU  - Simmons,
AU  - C.
AU  - Meiser-Stedman,
AU  - R.
AU  - Baily,
AU  - H.
AU  - Beazley,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/20008198.2021.1947570
L1  - internal-pdf://0596266465/Simmons-2021-A meta-analysis of dropout from e.pdf
PY  - 2021
SP  - 1947570
T2  - European Journal of Psychotraumatology
TI  - A meta-analysis of dropout from evidence-based psychological treatment for post-traumatic stress disorder (PTSD) in children and young people
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34377359
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344790/pdf/ZEPT_12_1947570.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: We examined whether anti-Black cultural racism moderates the efficacy of psychotherapy interventions among youth.

**METHOD**: We analyzed a subset of studies from a previous meta-analysis of five decades of youth psychotherapy randomized controlled trials. Studies were published in English between 1963 and 2017 and identified through a systematic search. The 194 studies (N = 14,081; ages 2-19) across 34 states comprised 2,678 effect sizes (ESs) measuring mental health problems (e.g., depression) targeted by interventions. Anti-Black cultural racism was operationalized using a composite index of 31 items measuring explicit racial attitudes (obtained from publicly available sources; e.g., General Social Survey), aggregated to the state level and linked to the meta-analytic database. Analyses were conducted with samples of majority (i.e., &gt;=50%) Black (n = 36 studies) and majority-White (n = 158 studies) youth. 

**RESULTS**: Two-level random effects meta-regression analyses indicated that higher anti-Black cultural racism was associated with lower ESs for studies with majority-Black youth (beta = -0.2, 95% CI: -0.35, -0.04, p = .02) but was unrelated to ESs for studies with majority-White youth (beta = 0.0004, 95% CI: -0.03, 0.03, p = .98), controlling for relevant area-level covariates. In studies with majority-Black youth, mean ESs were significantly lower in states with the highest anti-Black cultural racism (&gt;1 SD above the mean; g = 0.19) compared to states with the lowest racism (&lt;1 SD below the mean; g = 0.60). 

**CONCLUSION**: Psychotherapy randomized controlled trials with samples comprised of majority-Black youth were significantly less effective in states with higher (vs. lower) levels of anti-Black cultural racism, suggesting that anti-Black cultural racism may be one contextual moderator of treatment effect heterogeneity.
AN  - 34371101
AU  - Price,
AU  - M.
AU  - A.
AU  - Weisz,
AU  - J.
AU  - R.
AU  - McKetta,
AU  - S.
AU  - Hollinsaid,
AU  - N.
AU  - L.
AU  - Lattanner,
AU  - M.
AU  - R.
AU  - Reid,
AU  - A.
AU  - E.
AU  - Hatzenbuehler,
AU  - M.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2021.07.808
L1  - internal-pdf://1369982949/Price-2021-Meta-analysis_ Are Psychotherapies.pdf
PY  - 2021
SP  - 04
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Meta-analysis: Are Psychotherapies Less Effective for Black Youth in Communities With Higher Levels of Anti-Black Racism?
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34371101
VL  - 04
ER  -
TY  - JOUR
AB  - Mental health courts (MHCs) are increasingly used across the United States as a means of reducing contact with the criminal justice system for individuals experiencing serious mental health conditions. MHCs rely on diversion from incarceration to rehabilitation, services, and treatment to reduce recidivism and other negative outcomes among individuals with mental health disorders. While MHCs are a potential evidence-based remedy for the intensifying mental health and criminal justice crises in America, there is limited research indicating the overall effects these courts have on recidivism, and whether the effects vary across different sub-groups or research design and analytic features. Therefore, we present a meta-analysis of 38 effect sizes collected from 30 evaluations conducted from 1997 through 2020 on the impact of mental health courts on recidivism for adults and juveniles with mental health issues in the United States. Weighted meta-analytic results indicate that MHC participation corresponds to a 74% decrease in recidivism (OR = 0.26). Notably, the strength of MHC effects are similar for adult and juvenile participants, and stable across varied follow-up periods, study design features, and when prior criminal history, gender and race/ethnicity are controlled for in the analyses. Implications for the criminal justice system are also discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-65257-001
AU  - Fox,
AU  - B.
AU  - Miley,
AU  - L.
AU  - N.
AU  - Kortright,
AU  - K.
AU  - E.
AU  - Wetsman,
AU  - R.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12103-021-09629-6
L1  - internal-pdf://0230725056/Fox-2021-Assessing the effect of mental health.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - American Journal of Criminal Justice
TI  - Assessing the effect of mental health courts on adult and juvenile recidivism: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-65257-001
UR  - https://link.springer.com/content/pdf/10.1007/s12103-021-09629-6.pdf
ER  -
TY  - JOUR
AB  - **BACKGROUND**: As preterm infants&#039; neurodevelopment is shaped by NICU-related factors during their hospitalization, it is essential to evaluate which interventions are more beneficial for their neurodevelopment at this specific time. The objective of this systematic review and meta-analysis was to evaluate the effectiveness of interventions initiated during NICU hospitalization on preterm infants&#039; early neurodevelopment during their hospitalization and up to two weeks corrected age (CA).

**METHODS**: This systematic review referred to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses [PRISMA] guidelines and was registered in PROSPERO (CRD42017047072). We searched CINAHL, MEDLINE, PubMed, EMBASE (OVID), Cochrane Systematic Reviews, CENTRAL, and Web of Science from 2002 to February 2020 and included randomized controlled/clinical trials conducted with preterm infants born between 24 and 36&lt;sup&gt;6/7&lt;/sup&gt; weeks of gestation. All types of interventions instigated during NICU hospitalization were included. Two independent reviewers performed the study selection, data extraction, assessment of risks of bias and quality of evidence.

**RESULTS**: Findings of 12 studies involving 901 preterm infants were synthesized. We combined three studies in a meta-analysis showing that compared to standard care, the NIDCAP intervention is effective in improving preterm infants&#039; neurobehavioral and neurological development at two weeks CA. We also combined two other studies in a meta-analysis indicating that parental participation did not significantly improve preterm infants&#039; neurobehavioral development during NICU hospitalization. For all other interventions (i.e., developmental care, sensory stimulation, music and physical therapy), the synthesis of results shows that compared to standard care or other types of comparators, the effectiveness was either controversial or partially effective.

**CONCLUSIONS**: The overall quality of evidence was rated low to very low. Future studies are needed to identify interventions that are the most effective in promoting preterm infants&#039; early neurodevelopment during NICU hospitalization or close to term age. Interventions should be appropriately designed to allow comparison with previous studies and a combination of different instruments could provide a more global assessment of preterm infants&#039; neurodevelopment and thus allow for comparisons across studies.TRIAL REGISTRATION: Prospero CRD42017047072 .
AD  - Aita, Marilyn. Faculty of Nursing, Universite de Montreal, P.O. Box 6128, Succursale centre-ville, Montreal, QC, H3C 3J7, Canada. marilyn.aita@umontreal.ca.Aita, Marilyn. CHU Sainte-Justine Research Centre, 3175, chemin de la Cote-Sainte-Catherine, Montreal, QC, H3T 1C5, Canada. marilyn.aita@umontreal.ca.Aita, Marilyn. Quebec Network on Nursing Intervention Research, PO Box 6128, Centre-ville, Montreal, QC, H3C 3J7, Canada. marilyn.aita@umontreal.ca.De Clifford Faugere, Gwenaelle. Faculty of Nursing, Universite de Montreal, P.O. Box 6128, Succursale centre-ville, Montreal, QC, H3C 3J7, Canada.De Clifford Faugere, Gwenaelle. CHU Sainte-Justine Research Centre, 3175, chemin de la Cote-Sainte-Catherine, Montreal, QC, H3T 1C5, Canada.Lavallee, Andreane. Faculty of Nursing, Universite de Montreal, P.O. Box 6128, Succursale centre-ville, Montreal, QC, H3C 3J7, Canada.Lavallee, Andreane. CHU Sainte-Justine Research Centre, 3175, chemin de la Cote-Sainte-Catherine, Montreal, QC, H3T 1C5, Canada.Feeley, Nancy. Quebec Network on Nursing Intervention Research, PO Box 6128, Centre-ville, Montreal, QC, H3C 3J7, Canada.Feeley, Nancy. Ingram School of Nursing, McGill University, 680 Rue Sherbrooke Ouest #1800, Montreal, QC, H3A 2M7, Canada.Feeley, Nancy. Centre for Nursing Research and Lady Davis Institute, Jewish General Hospital, 3755 Chemin de la Cote-Sainte-Catherine, Montreal, QC, H3T 1E2, Canada.Stremler, Robyn. Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, 155 College St, Toronto, ON, M5T 1P8, Canada.Stremler, Robyn. Hospital for Sick Children (SickKids), 555 University Ave, Toronto, ON, M5G 1X8, Canada.Rioux, Emilie. Faculty of Nursing, Universite de Montreal, P.O. Box 6128, Succursale centre-ville, Montreal, QC, H3C 3J7, Canada.Rioux, Emilie. Jewish General Hospital, 3755 Chemin de la Cote-Sainte-Catherine, Montreal, QC, H3T 1E2, Canada.Proulx, Marie-Helene. Faculty of Nursing, Universite de Montreal, P.O. Box 6128, Succursale centre-ville, Montreal, QC, H3C 3J7, Canada.
AN  - 33926417
AU  - Aita,
AU  - M.
AU  - De
AU  - Clifford
AU  - Faugere,
AU  - G.
AU  - Lavallee,
AU  - A.
AU  - Feeley,
AU  - N.
AU  - Stremler,
AU  - R.
AU  - Rioux,
AU  - E.
AU  - Proulx,
AU  - M.
AU  - H.
DA  - 04 29
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12887-021-02559-6
DP  - Ovid Technologies
J2  - BMC Pediatr
KW  - *Hospitalization
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - *Infant, Premature
KW  - Parents
L1  - internal-pdf://3598597541/Aita-2021.pdf
LA  - English
M3  - Meta-Analysis
Research Support, Non-U.S. Gov&#039;t
Systematic Review
N1  - Aita, MarilynDe Clifford Faugere, GwenaelleLavallee, AndreaneFeeley, NancyStremler, RobynRioux, EmilieProulx, Marie-Helene
PY  - 2021
SP  - 210
T2  - BMC Pediatrics
TI  - Effectiveness of interventions on early neurodevelopment of preterm infants: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=33926417
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33926417&amp;id=doi:10.1186%2Fs12887-021-02559-6&amp;issn=1471-2431&amp;isbn=&amp;volume=21&amp;issue=1&amp;spage=210&amp;pages=210&amp;date=2021&amp;title=BMC+Pediatrics&amp;atitle=Effectiveness+of+interventions+on+early+neurodevelopment+of+preterm+infants%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Aita&amp;pid=%3Cauthor%3EAita+M%3C%2Fauthor%3E%3CAN%3E33926417%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082967/pdf/12887_2021_Article_2559.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - **INTRODUCTION**
This study aims to report the effect sizes of telemedicine treatments on the symptom domains of paediatric ADHD. 

**METHODS**
In this systematic review and meta-analysis, electronic databases, i.e. PubMed, Scopus, Web of Science and Embase, were searched for articles published up to December 2020. The inclusion criteria were as follows: children or adolescents diagnosed for ADHD or other hyperkinetic disorders; randomized controlled trials (RCTs); efficacy established with parents and teachers or self-rating scales at least for one of the following domains: inattention, cognitive function, hyperactivity, hyperactivity/impulsivity or oppositional behaviours. The risk of bias was assessed using the Cochrane risk of bias tool for RCTs. 

**RESULTS**
From 310 records reduced to 228 after removing duplicates, overall 12 studies were fulfilled our inclusion criteria. They consisted of 708 participants (358 with telemedicine intervention and 350 controls). The telemedicine interventions varied from computerized training programmes with phone calls to videoconferencing programmes, virtual reality classrooms or games. The most applicable method consisted of computerized training programmes with phone calls. Pooling results of all studies with available data on each subscale showed a significant effect of telemedicine on inattention/cognitive function (standardized mean difference (SMD) = 0.26, 95% CI: 0.16, 0.36), hyperactivity/impulsivity (SMD = 0.29, 95% CI: 0.06, 0.52), and oppositional behaviours (SMD = 0.72, 95% CI: 0.24, 1.20) subscales in ADHD. Almost all studies had an overall unclear risk of bias. The source of outcome assessment (parents, teachers or self-report questionnaire) was addressed as a potential confounding factor. In almost all symptom domains, the satisfaction from the treatment was higher in parents than in teachers. 

**CONCLUSIONS**
 The clinical effects of telemedicine on the treatment of ADHD showed a small effect size for inattention/cognitive function, hyperactivity/impulsivity and oppositional behaviours.
AN  - 34633251
AU  - Bemanalizadeh,
AU  - M.
AU  - Yazdi,
AU  - M.
AU  - Yaghini,
AU  - O.
AU  - Kelishadi,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1357633X211045186
L1  - internal-pdf://0632269260/Bemanalizadeh-2021-A meta-analysis on the effe.pdf
PY  - 2021
SP  - 1357633X211045186
T2  - Journal of Telemedicine &amp; Telecare
TI  - A meta-analysis on the effect of telemedicine on the management of attention deficit and hyperactivity disorder in children and adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34633251
UR  - https://journals.sagepub.com/doi/10.1177/1357633X211045186
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1357633X211045186
ER  -
TY  - JOUR
AB  - **Introduction: **
Amongst its advocates, one of the key arguments for a Universal Basic Income (UBI) is its potential to improve population mental health. However, while previous authors have variously examined the potential effects of UBI on income, employment and labour market demand, the direct mental health consequences of previous pilots have been less frequently examined. The purpose of this paper is therefore to conduct a review of the literature on UBI and to re-examine the existing research with a mental health focus. 

**Method(s): **
Six electronic databases were used to conduct a review of the literature. We searched for empirical research studies of any design, conducted since the year 2000 in High Income Countries, exploring the effects of interventions similar to a UBI on the mental health of children or working-age adults. Grey literature and government reports were also included. 

**Result(s): **
A total of 1566 articles were screened of which seven peer reviewed studies and eight governmental reports were ultimately selected for inclusion. None of the identified studies directly compared the impact of individual payments with those made on a household basis, or the effects of payments which were truly universal. However, several studies evaluated the mental health outcomes associated with payments provided unconditionally, and consistently reported clear and significant improvements in mental wellbeing. Potential mediating factors included improved time with family and friends, a reduction in perceived stigma and a renewed sense of hope for the future. 

**Conclusion(s):** 
Our review has produced evidence to suggest that prophesies surrounding the mental health benefits of a UBI are at least partially justified. However, future studies should aim to be conducted at an area level, with an adequately powered sample size, and investigate interventions of a considerable duration using a longitudinal design. 

Copyright &copy; 2021 Elsevier Ltd
AN  - 2014566644
AU  - Wilson,
AU  - N.
AU  - McDaid,
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.socscimed.2021.114374
L1  - internal-pdf://3595452711/Wilson-2021-The mental health effects of a Uni.pdf
PY  - 2021
T2  - Social Science and Medicine
TI  - The mental health effects of a Universal Basic Income: A synthesis of the evidence from previous pilots
UR  - http://www.elsevier.com/locate/socscimed
VL  - 287 (no pagination)
ER  -
TY  - JOUR
AB  - The current study aimed to provide a comprehensive appraisal of the current evidence on the effectiveness of Pivotal Response Training (PRT) for individuals with autism spectrum disorder (ASD) and to explore predictors of treatment response. We conducted a systematic review of the following electronic databases and registers: PsycINFO, Medline, Embase, Cochrane Central Register of Controlled Trials, ERIC, Linguistics and Language Behavior Abstracts. Six systematic reviews were identified, two with meta-analytic component. Identified reviews varied widely in terms of their aims, outcomes, and designs which precluded a unified and consistent set of conclusions and recommendations. Ten RCTs were identified. Eight of identified RCTs reported at least one language and communication-related outcome. Statistically significant effects of PRT were identified across a majority of identified RCTs for a range of language and communication skills. However, evidence for positive treatment effects of PRT on outcome measures assessing other domains was less robust and/or specific. Overall, both previous systematic reviews and new meta-analysis of the RCTs suggest that PRT shows promise for improving language and communication. Only four RCTs examined the association between baseline child characteristics and treatment outcomes, however, no consistent pattern emerged. This review has identified several key methodological and design improvements that are needed to enable our field to fully capitalize on the potential of RCT designs and characterize detailed profiles of treatment responders. These findings are essential for informing the development of evidence-based guidelines for clinicians on what works for whom and why.
AN  - 35153850
AU  - Uljarevic,
AU  - M.
AU  - Billingham,
AU  - W.
AU  - Cooper,
AU  - M.
AU  - N.
AU  - Condron,
AU  - P.
AU  - Hardan,
AU  - A.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2021.766150
L1  - internal-pdf://0580652305/Examining Effectiveness and Predictors of-2021.pdf
PY  - 2021
SP  - 766150
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Examining Effectiveness and Predictors of Treatment Response of Pivotal Response Treatment in Autism: An Umbrella Review and a Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35153850
VL  - 12
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Youth suicide prevention in high-schools and universities is a public health priority. Our aim was to propose a research agenda to advance evidence-based suicide prevention in high-schools and universities by synthesizing and critically reviewing the research focus and methodologies used in existing intervention studies. 

**METHODS**: Fourteen databases were systematically searched to identify studies which evaluate suicide prevention interventions delivered on high-school or university campuses, with before and after measures. Data from included studies (n = 43) were extracted to identify what, where, how and for whom interventions have been tested. Narrative synthesis was used to critically evaluate research focus and methodology. Study quality was assessed. 

**RESULTS**: Research has focused primarily on selective interventions, with less attention on indicated and universal interventions. Most evidence comes from North America and high-income countries. The target of interventions has been: non-fatal suicidal behaviour; confidence and ability of staff/students to intervene in a suicidal crisis; suicide-related knowledge and attitudes; and suicide-related stigma. No studies included suicide deaths as an outcome, evaluated eco-systemic interventions, explored how context influences implementation, used multisite study designs, or focused explicitly on LGBTQ+ youth. Two studies evaluated digital interventions. Quality of the majority of studies was compromised by lack of methodological rigour, small samples, and moderate/high risk of bias. Interventions often assume the existence of an external well-functioning referral pathway, which may not be true in low-resource settings. 

**CONCLUSION**: To advance evidence-based suicide prevention in educational settings we need to: conduct more high-quality clinical and pragmatic trials; promote research in low- and middle-income countries; test targeted interventions for vulnerable populations (like LGBTQ+ youth), evaluate interventions where death by suicide is the primary outcome; include translational studies and use implementation science to promote intervention uptake; evaluate the potential use of digital and eco-systemic interventions; and conduct multisite studies in diverse cultural settings.
AN  - 34112141
AU  - Breet,
AU  - E.
AU  - Matooane,
AU  - M.
AU  - Tomlinson,
AU  - M.
AU  - Bantjes,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12889-021-11124-w
L1  - internal-pdf://3976354990/Breet-2021-Systematic review and narrative syn.pdf
PY  - 2021
SP  - 1116
T2  - BMC Public Health
TI  - Systematic review and narrative synthesis of suicide prevention in high-schools and universities: a research agenda for evidence-based practice
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med18&amp;AN=34112141
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8194002/pdf/12889_2021_Article_11124.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - **Background **
Physical activity among children and adolescents is associated with lower adiposity, improved cardio‐metabolic health, and improved fitness. Worldwide, fewer than 30% of children and adolescents meet global physical activity recommendations of at least 60 minutes of moderate to vigorous physical activity per day. Schools may be ideal sites for interventions given that children and adolescents in most parts of the world spend a substantial amount of time in transit to and from school or attending school. 

**Objectives **
The purpose of this review update is to summarise the evidence on effectiveness of school‐based interventions in increasing moderate to vigorous physical activity and improving fitness among children and adolescents 6 to 18 years of age. Specific objectives are: &bull; to evaluate the effects of school‐based interventions on increasing physical activity and improving fitness among children and adolescents; &bull; to evaluate the effects of school‐based interventions on improving body composition; and &bull; to determine whether certain combinations or components (or both) of school‐based interventions are more effective than others in promoting physical activity and fitness in this target population. 

**Search methods **
We searched CENTRAL, MEDLINE, Embase, CINAHL, PsycINFO, BIOSIS, SPORTDiscus, and Sociological Abstracts to 1 June 2020, without language restrictions. We screened reference lists of included articles and relevant systematic reviews. We contacted primary authors of studies to ask for additional information. 

**Selection criteria **
Eligible interventions were relevant to public health practice (i.e. were not delivered by a clinician), were implemented in the school setting, and aimed to increase physical activity among all school‐attending children and adolescents (aged 6 to 18) for at least 12 weeks. The review was limited to randomised controlled trials. For this update, we have added two new criteria: the primary aim of the study was to increase physical activity or fitness, and the study used an objective measure of physical activity or fitness. Primary outcomes included proportion of participants meeting physical activity guidelines and duration of moderate to vigorous physical activity and sedentary time (new to this update). Secondary outcomes included measured body mass index (BMI), physical fitness, health‐related quality of life (new to this update), and adverse events (new to this update). Television viewing time, blood cholesterol, and blood pressure have been removed from this update. 

**Data collection and analysis **
Two independent review authors used standardised forms to assess each study for relevance, to extract data, and to assess risk of bias. When discrepancies existed, discussion occurred until consensus was reached. Certainty of evidence was assessed according to GRADE. A random‐effects meta‐analysis based on the inverse variance method was conducted with participants stratified by age (children versus adolescents) when sufficient data were reported. Subgroup analyses explored effects by intervention type. 

**Main results **
Based on the three new inclusion criteria, we excluded 16 of the 44 studies included in the previous version of this review. We screened an additional 9968 titles (search October 2011 to June 2020), of which 978 unique studies were potentially relevant and 61 met all criteria for this update. We included a total of 89 studies representing complete data for 66,752 study participants. Most studies included children only (n = 56), followed by adolescents only (n = 22), and both (n = 10); one study did not report student age. Multi‐component interventions were most common (n = 40), followed by schooltime physical activity (n = 19), enhanced physical education (n = 15), and before and after school programmes (n = 14); one study explored both enhanced physical education and an after school programme. Lack of blinding of participants, personnel, and outcome assessors and loss to follow‐up were the most common sources of bias. 

Results sho that school‐based physical activity interventions probably result in little to no increase in time engaged in moderate to vigorous physical activity (mean difference (MD) 0.73 minutes/d, 95% confidence interval (CI) 0.16 to 1.30; 33 studies; moderate‐certainty evidence) and may lead to little to no decrease in sedentary time (MD ‐3.78 minutes/d, 95% CI ‐7.80 to 0.24; 16 studies; low‐certainty evidence). School‐based physical activity interventions may improve physical fitness reported as maximal oxygen uptake (VO₂max) (MD 1.19 mL/kg/min, 95% CI 0.57 to 1.82; 13 studies; low‐certainty evidence). School‐based physical activity interventions may result in a very small decrease in BMI z‐scores (MD ‐0.06, 95% CI ‐0.09 to ‐0.02; 21 studies; low‐certainty evidence) and may not impact BMI expressed as kg/m&sup2; (MD ‐0.07, 95% CI ‐0.15 to 0.01; 50 studies; low‐certainty evidence). We are very uncertain whether school‐based physical activity interventions impact health‐related quality of life or adverse events. 

**Authors&#039; conclusions **
Given the variability of results and the overall small effects, school staff and public health professionals must give the matter considerable thought before implementing school‐based physical activity interventions. Given the heterogeneity of effects, the risk of bias, and findings that the magnitude of effect is generally small, results should be interpreted cautiously.
AN  - CD007651
AU  - Neil-Sztramko,
AU  - S.
AU  - E.
AU  - Caldwell,
AU  - H.
AU  - Dobbins,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1002/14651858.CD007651.pub3
KW  - *Health Promotion
KW  - *Schools
KW  - Adolescent
KW  - Child
KW  - Exercise [*physiology]
KW  - Humans
KW  - Motor Activity
KW  - Physical Fitness [*physiology]
KW  - Program Evaluation
KW  - Randomized Controlled Trials as Topic
N1  - [Public Health]
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - School‐based physical activity programs for promoting physical activity and fitness in children and adolescents aged 6 to 18
UR  - http://dx.doi.org/10.1002/14651858.CD007651.pub3
ER  -
TY  - JOUR
AB  - **Background** Selective mutism is a rare childhood anxiety disorder characterized by a consistent failure to speak in certain social situations where speech is expected, despite fluent speech in other situations. The purpose of this meta-analysis was to investigate the efficacy of psychological interventions for selective mutism in randomized controlled trials (RCTs). 

**Methods** Five RCTs with a total of 233 participants were analysed using a random-effects model. A quality assessment of the included studies revealed that psychometrically sound measures and treatment manuals were used across all studies. 

**Results** The results of the analyses showed psychological interventions to be more effective than no treatment, with the overall weighted effect size of g = 0.87, indicating a large mean treatment effect. This effect did not significantly differ with whether only selective mutism specific or nonselective mutism specific measures were included in the analysis. 

**Conclusions** These findings provide support for the efficacy of psychological treatment for selective mutism. Future research could examine the effects of the successful treatments identified in this meta-analysis when compared with a psychological placebo or another bona fide treatment.
AN  - WOS:000678792500001
AU  - Steains,
AU  - S.
AU  - Y.
AU  - Malouff,
AU  - J.
AU  - M.
AU  - Schutte,
AU  - N.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/cch.12895
L1  - internal-pdf://0954917762/Steains-Efficacy of psychological intervention.pdf
PY  - 2021
SP  - 11
T2  - Child Care Health and Development
TI  - Efficacy of psychological interventions for selective mutism in children: A meta-analysis of randomized controlled trials
UR  - &lt;Go to ISI&gt;://WOS:000678792500001
UR  - https://onlinelibrary.wiley.com/doi/10.1111/cch.12895
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/cch.12895?download=true
ER  -
TY  - JOUR
AB  - **Background**
Trichotillomania (TTM; hair‐pulling disorder) is a prevalent and disabling disorder characterised by recurrent hair‐pulling. Here we update a previous Cochrane Review on the effects of medication for TTM.

**Objectives**
To assess the effects of medication for trichotillomania (TTM) in adults, children and adolescents compared with placebo or other medication.

**Search methods**
We searched CENTRAL, MEDLINE, Embase, PsycINFO, eleven other bibliographic databases, trial registries and grey literature sources (to 26 November 2020). We checked reference lists and contacted subject experts.

**Selection criteria**
We selected randomised controlled trials of medication versus placebo or other medication for TTM in adults, children and adolescents.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane.

**Main results**
Twelve studies were included. We identified 10 studies in adults (286 participants) with a mean sample size of 29 participants per trial; one study in children and adolescents (39 participants); and, one study in adults and adolescents (22 participants: 18 adults and 4 adolescents). All studies were single‐centre, outpatient trials. Eleven studies compared medication and placebo (334 participants); one study compared two medications (13 participants). Studies were 5 to 13 weeks duration. We undertook meta‐analysis only for opioid antagonists as other comparisons contained a single study, or reported insufficient data.

Antioxidants versus placebo in adults

There was little to no difference in treatment response between antioxidant (35.7%) and placebo groups (28.6%) after six weeks, based on a single trial of silymarin (risk ratio (RR) 2.25, 95% confidence interval (CI) 0.84 to 5.99; 36 participants; low‐certainty evidence). We could not calculate differences in number of dropouts as there were no events in either group (18 participants; low‐certainty evidence).

Antioxidants versus placebo in adolescents

There was little to no difference in treatment response between antioxidant (50%) and placebo groups (25%) after six weeks, based on a single trial of silymarin (RR 2.00, 95% CI 0.28 to 14.20; 8 participants; low‐certainty evidence). We could not calculate differences in number of dropouts as there were no events in either group (8 participants; low‐certainty evidence).

Antipsychotics versus placebo in adults

There may be greater treatment response in the antipsychotic group (85%) compared to the placebo group (17%) after 12 weeks, based on a single trial of olanzapine (RR 5.08, 95% CI 1.4 to 18.37; 25 participants; low‐certainty evidence). We could not calculate differences in number of dropouts as there were no events in either group (25 participants; low‐certainty evidence).

Cell signal transducers versus placebo in adults

There was little to no difference in treatment response between cell signal transducer (42.1%) and placebo groups (31.6%) after 10 weeks, based on a single trial of inositol (RR 1.33, 95% CI 0.57 to 3.11; 38 participants; low‐certainty evidence). We could not calculate differences in number of dropouts as there were no events in either group (38 participants; low‐certainty evidence).

Glutamate modulators versus placebo in adults

There is probably greater treatment response in the glutamate modulator group (56%) compared to the placebo group (16%) after 12 weeks, based on a single trial of N‐acetylcysteine (RR 3.5, 95% CI 1.34 to 9.17; 50 participants; moderate‐certainty evidence). We could not calculate differences in number of dropouts as there were no events in either group (50 participants; low‐certainty evidence).

Glutamate modulators versus placebo in children and adolescents

There was little to no difference in treatment response between the glutamate modulator (25%) and placebo groups (21.1%) in children and adolescents, based on a single trial of N‐acetylcysteine (RR 1.19, 95% CI 0.37 to 3.77; 39 participants; low‐certainty evidence). There was little to no difference in dropouts due to adverse events between glutamate modulator (5%) and placebo (0%) groups, based on a single trial (RR 2.86, 95% CI 0.12 to 66.11; 39 participants; low‐certainty evidence).

Opioid antagonists versus placebo in adults

There may be little to no difference in treatment response between opioid antagonist (37.5%) and placebo groups (25%) after six to eight weeks, based on two studies of naltrexone, but the evidence is very uncertain (RR 2.14, 95% CI 0.25 to 18.17; 2 studies, 68 participants; very low‐certainty evidence). No data were available regarding dropouts due to adverse events.

Selective serotonin reuptake inhibitors (SSRIs) versus placebo in adults

There were no data available for treatment response to SSRIs. There was little to no difference in dropouts due to adverse events in the SSRI group (5.1%) compared to the placebo group (0%) after 6 to 12 weeks, based on two trials of fluoxetine (RR 3.00, 95% CI 0.33 to 27.62; 2 studies, 78 participants; low‐certainty evidence).

Tricyclic antidepressants (TCAs) with predominantly serotonin reuptake inhibitor (SRI) actions versus placebo in adults

There may be greater treatment response in the TCAs with predominantly SRI actions group (40%) compared to the placebo group (0%) after nine weeks, but the evidence is very uncertain, based on a single trial of clomipramine (RR 5.73, 95% CI 0.36 to 90.83; 16 participants; very low‐certainty evidence). There may be increased dropouts due to adverse events in the TCAs with predominantly SRI actions group (30%) compared to the placebo group (0%), but the evidence is very uncertain (RR 4.45, 95% CI 0.27 to 73.81; 16 participants; very low‐certainty evidence).

TCAs with predominantly SRI actions versus other TCAs in adults

There may be greater treatment response in the TCAs with predominantly SRI actions group compared to the other TCAs group after five weeks, based on a single trial comparing clomipramine to desipramine (mean difference (MD) ‐4.00, 95% CI ‐6.13 to ‐1.87; 26 participants; low‐certainty evidence). We could not calculate differences in number of dropouts as there were no events in either group (26 participants; low‐certainty evidence).

**Authors&#039; conclusions**
There was insufficient evidence from meta‐analysis to confirm or refute the efficacy of any agent or class of medication for the treatment of TTM in adults, children or adolescents. Preliminary evidence suggests there may be beneficial treatment effects for N‐acetylcysteine, clomipramine and olanzapine in adults based on four trials, albeit with relatively small sample sizes.
AN  - CD007662
AU  - Hoffman,
AU  - J.
AU  - Williams,
AU  - T.
AU  - Rothbart,
AU  - R.
AU  - Ipser,
AU  - J.
AU  - C.
AU  - Fineberg,
AU  - N.
AU  - Chamberlain,
AU  - S.
AU  - R.
AU  - Stein,
AU  - D.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD007662.pub3
KW  - *Antipsychotic Agents [therapeutic use]
KW  - *Trichotillomania [drug therapy]
KW  - Adolescent
KW  - Antidepressive Agents, Tricyclic [therapeutic use]
KW  - Clomipramine
KW  - Humans
KW  - Selective Serotonin Reuptake Inhibitors
L1  - internal-pdf://3522243970/Hoffman_et_al-2021-Cochrane_Database_of_System.pdf
N1  - [Common Mental Disorders]
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - Pharmacotherapy for trichotillomania
UR  - https://doi.org//10.1002/14651858.CD007662.pub3
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Mindful parenting is the process of bringing awareness and attention intentionally in a non-reactive and non-judgemental way to a child at any present moment. Parenting mindfulness is believed to influence parenting factors and parental psychological outcomes, child&#039;s emotional and behavioural outcomes, and family relationships. However, the efficacy of such interventions on interpersonal mindfulness in parenting and parenting behaviours has received minimal empirical attention. 

**OBJECTIVE**: This meta-analysis aims to quantitatively evaluate the efficacy of mindful parenting interventions on parenting mindfulness and parenting behaviours. Parenting stress, parents&#039; psychological wellbeing, interpersonal relationships, and child behavioural outcomes were examined secondarily. When meta-analysis was not possible (due to insufficient data in the included studies), the narrative approach was taken to present the findings. 

**DESIGN**: A systematic review, meta-analysis, and narrative summary. 

**METHODS**: Six electronic databases (PubMed, Embase, PsycINFO, CINAHL, Scopus, and ProQuest Dissertations and Theses) were systematically searched for articles in the English language from their respective dates of inception to December 2020. Studies involving clinical and non-clinical samples of parents with children or youths aged 24 years and below were included. Only randomised controlled trials were included. Studies were excluded if the mindfulness intervention did not focus on parenting skills training; that is, it focused on childbirth, stress reduction or incorporated other forms of therapy (e.g. cognitive behavioural therapy). Data was synthesised using a random-effects model in RevMan 5.4. The outcomes of primary interest were parenting mindfulness and parenting behaviours. The secondary outcomes were parenting stress, parents&#039; psychological wellbeing, interpersonal relationships, and child behavioural outcomes. 

**RESULTS**: Eleven studies representing 1,340 parents from six countries were included in the review. No evidence of intervention effect was found for overall parenting mindfulness and overall parenting stress. However, mindful parenting interventions demonstrated a moderate effect size when examining parenting mindfulness scores (standardised mean differences (d)=0.62, 95% CI: 0.11, 1.13, p = 0.02) of parents with non-clinical samples of children. No intervention effect was found for overall parenting stress. Due to insufficient studies and data, findings on parenting behaviours, psychological wellbeing, relationships, and child behaviour were presented narratively. 

**CONCLUSION**: Mindful parenting interventions are associated with higher parenting mindfulness scores for parents of typically developing children when compared with a control group. The limited studies and mixed results on positive parenting behaviours, parental psychological wellbeing, parental relationship with child and partner, and child behavioural outcomes serve as an impetus for further research.
AN  - 34175531
AU  - Shorey,
AU  - S.
AU  - Ng,
AU  - E.
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ijnurstu.2021.103996
L1  - internal-pdf://1121770449/Shorey-2021-The efficacy of mindful parenting.pdf
PY  - 2021
SP  - 103996
T2  - International Journal of Nursing Studies
TI  - The efficacy of mindful parenting interventions: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34175531
VL  - 121
ER  -
TY  - JOUR
AB  - **Introduction**: Effective adolescent learning programmes can positively influence adolescent development and curb risky behaviour. By immersing learners in an experience, experiential learning motivates learners to reflect on the experience to transform and create new skills, attitudes and ways of thinking. However, evidence of its effectiveness in learning programs facilitating positive youth development is still lacking. 

The objective of this study is to (a) identify the effect of adolescent learning programmes on prosocial behaviour, empathy and subjective well-being, (b) compare the effectiveness of experiential learning programmes and non-experiential learning programmes on improving these three outcomes, and (c) evaluating the effects of age on the outcomes of adolescent learning programmes. 

**Methods**: This study was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Randomised controlled trials of learning programmes for typically developing adolescents aged 8-25 in the past 15 years were identified, and assessed for quality with the Physiotherapy Evidence Database (PEDRO) scale. One thousand ninety-six records were screened with the inclusion and exclusion criteria, and 20 studies were adopted for this meta-analysis. The standardised mean difference and 95% confidence interval (CI) of the effect of experiential learning program on empathy, prosocial behaviour, and subjective well-being were examined. Sub-group analysis based on age was conducted to examine the effects of experiential learning on adolescents in different stages of life. 

**Results**: Experiential learning programmes were more effective than non-experiential learning programmes in improving empathy [d = 0.65 (0.07, 1.23)] and subjective well-being [d = 0.46 (0.33, 0.59)]. The effect sizes of the three outcomes in non-experiential learning programmes were non-significant. Studies conducted on older adolescents had the most significant improvements in the three outcomes. 

**Conclusions**: Results suggest the broader application of experiential learning in adolescent learning programmes for older adolescents in the future to promote positive youth development.
AN  - WOS:000686560800001
AU  - Chan,
AU  - H.
AU  - H.
AU  - K.
AU  - Kwong,
AU  - H.
AU  - Y.
AU  - C.
AU  - Shu,
AU  - G.
AU  - L.
AU  - F.
AU  - Ting,
AU  - C.
AU  - Y.
AU  - Lai,
AU  - F.
AU  - H.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.childyouth.2021.106136
L1  - internal-pdf://2867407545/Chan-2021-Effects of Experiential Learning Pro.pdf
PY  - 2021
SP  - 18
T2  - Frontiers in Psychology
TI  - Effects of Experiential Learning Programmes on Adolescent Prosocial Behaviour, Empathy, and Subjective Well-being: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000686560800001
VL  - 12
ER  -
TY  - JOUR
AB  - **BACKGROUND** Infants born preterm are known to be at risk for abnormal brain development and adverse neurobehavioral outcomes. To improve early neurodevelopment, several non-pharmacological interventions have been developed and implemented in the neonatal intensive care unit (NICU). Sensory-based interventions seem to improve short-term neurodevelopmental outcomes in the inherently stressful NICU environment. However, how this type of intervention affects brain development in the preterm population remains unclear. 

**METHODS** 
A systematic review of the literature was conducted for published studies in the past 20 years reporting the effects of early, non-pharmacological, sensory-based interventions on the neonatal brain after preterm birth. 

**RESULTS** 
Twelve randomized controlled trials (RCT) reporting short-term effects of auditory, tactile, and multisensory interventions were included after the screening of 1202 articles. Large heterogeneity was identified among studies in relation to both types of intervention and outcomes. Three areas of focus for sensory interventions were identified: auditory-based, tactile-based, and multisensory interventions. 

**CONCLUSIONS** 
Diversity in interventions and outcome measures challenges the possibility to perform an integrative synthesis of results and to translate these for evidence-based clinical practice. This review identifies gaps in the literature and methodological challenges for the implementation of RCTs of sensory interventions in the NICU. 

**IMPACT** 
This paper represents the first systematic review to investigate the effect of non-pharmacological, sensory-based interventions in the NICU on neonatal brain development. Although reviewed RCTs present evidence on the impact of such interventions on the neonatal brain following preterm birth, it is not yet possible to formulate clear guidelines for clinical practice. This review integrates existing literature on the effect of sensory-based interventions on the brain after preterm birth and identifies methodological challenges for the conduction of high-quality RCTs.
AN  - 34508227
AU  - Beltran,
AU  - M.
AU  - I.
AU  - Dudink,
AU  - J.
AU  - de
AU  - Jong,
AU  - T.
AU  - M.
AU  - Benders,
AU  - Mjnl
AU  - van
AU  - den
AU  - Hoogen,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1038/s41390-021-01718-w
L1  - internal-pdf://1947343586/Beltran-2021-Sensory-based interventions in th.pdf
PY  - 2021
SP  - 10
T2  - Pediatric Research
TI  - Sensory-based interventions in the NICU: systematic review of effects on preterm brain development
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34508227
UR  - https://www.nature.com/articles/s41390-021-01718-w.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - Dietary recommendations have been proposed as a way of impacting current and future mental health. There exists a limited body of conflicting literature related to pediatric nutritional interventions and depression. This meta-analysis aims to determine the efficacy of child and adolescent dietary interventions on depression. Systematic searches in electronic databases and gray literature were conducted. After screening 6725 citations, 17 studies were included in this systematic review. Quality assessment was performed using the Cochrane risk-of-bias tool and the Joanna Briggs Institute Critical Appraisal Tool for Quasi-Experimental Studies. A meta-analysis of Hedges g values was calculated using the Hartung-Knapp-Sidik-Jonkman method. Publication bias was assessed with funnel plots and the Egger test. The results of the meta-analysis of the RCTs (k = 7) demonstrated a nonsignificant effect of dietary intervention (g = 0.05; 95% CI: -0.25, 0.35; P = 0.70) whereas the results of the pre-post intervention studies (k = 9) demonstrated a significant small-to-medium effect favoring dietary intervention for reducing depression (g = -0.45; 95% CI: -0.64, -0.27; P = 0.001). Publication bias was not detected by the Egger test or by funnel plot asymmetry. The current meta-analysis demonstrates that &quot;healthy&quot; dietary interventions for children or adolescents in the community have little impact on nonclinical depression. Confusion will persist until better-designed studies in pediatric nutritional psychiatry research focusing on adolescents with depressive illness are conducted.
AN  - 34302170
AU  - Campisi,
AU  - S.
AU  - C.
AU  - Zasowski,
AU  - C.
AU  - Shah,
AU  - S.
AU  - Bradley-Ridout,
AU  - G.
AU  - Madigan,
AU  - S.
AU  - Szatmari,
AU  - P.
AU  - Korczak,
AU  - D.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/advances/nmab088
L1  - internal-pdf://2480088613/Campisi-2021-Do Healthy Dietary Interventions.pdf
PY  - 2021
SP  - 23
T2  - Advances in Nutrition
TI  - Do Healthy Dietary Interventions Improve Pediatric Depressive Symptoms? A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34302170
UR  - https://academic.oup.com/advances/advance-article-abstract/doi/10.1093/advances/nmab088/6327216?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/nmab088.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAwYwggMCBgkqhkiG9w0BBwagggLzMIIC7wIBADCCAugGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMO6jZgDU8xaFzO8ICAgEQgIICuWtKD6dJQ3AdhO-1_lqXuBNS51rhMInYG5DBBA6OjMFsbTZfdVwJiZeQRHkV2XsHPW8xN67OSjeV0LTqy2u4B5jj3dj4-rmrycnkcQHnHa_-75l72N7C6AGulKwJJr8ZJ7TMGJibVSgrcEV6tFj2yP_SueSBpMncjXfMwqPfQHZM5C7K_jG8nkM7fZxd39VRzdvlPLZYPtdiWFgi3qPhib-BdXdt-bEZB5LLb2HIeKwT1gT3-BfnQTRRxKgeOjQ_7TRAw39El1FdGtRo5614zf_YO1DuNkO6fNnAoRHqfSVuW24nIEpDT4wlhdk2nN6BrYCXuYAd0d6joM9kqN3LoB4JxFHGydGCTx6CuXaNS1Qq-BqeuWEl6slVaGpeXVBY43YfkHFAAtgiroFXi0huZe0NiLINpc4Pm2hqeJEHivspN-5ylYJv7BowsRpSKzF8EQb0P0UgDHtayH58QdVTYj7rOeXR8RHNPE-LbhTFtVkpuLTgPDCQfHjRcmxmQ-6rKDluZC_gkmXwxSezh836Aj5b3IJDVeFbj4xNjqHoR6EAek1qB14YHrfJaoYAyvmH9qS_O7V3HlqjMSHfNZRvru1w0jGiU0455x5YdC1PlGyl1iunQXdtX5x6FuqPRs7wKyN52Yp3c3avzndH4ctvQA3oYeU2tVXg190RZdmu1PmqynWVPyQSXCtoSdJjy1fuCPIgQj5YvOV_f3jvM_uop1XTWZkgg1TTaKP6RWg2PM9ShvoctVdqqrGHfRMzgXj6UXVC2rgXZrf_8UPycY3d57YdRf4HdkpEU165A8W2Tnib3G77o6nIGJaw5Pt7_Vd_DzpzQfMMwHUETJwc3he5T6WhHP2r01_7kybxxG3NxkDkeL8tThN82uNyJEMihpKDJEF0iLHHLC8bwhXlWQpg9RuFYQ7WLt8-Euc
VL  - 23
ER  -
TY  - JOUR
AB  - The ability to understand what one reads, or reading comprehension, is central to academic success. For many children with autism spectrum disorder (ASD), reading comprehension is a noted area of challenge. For children with typical development, it is well established that successful reading comprehension requires two broad skills: word reading and oral language. For children with ASD, word reading is often believed to be relatively intact, even in the face of poor reading comprehension, suggesting that deficits in oral language, more than in word reading, underlie reading comprehension deficits. Yet, extant research has suggested the importance of both skills. To clarify the role of these skills in the reading comprehension of children with ASD, we conducted a meta-analysis. ERIC, PsycINFO, PubMed, and Proquest Dissertation &amp; Theses were searched for studies of reading comprehension in children with ASD, published up to May 2019. We identified 26 relevant studies about children with ASD (aged 6-18 years) that included both a measure of word reading and reading comprehension. Hunt-Schmidt Random Effects Models showed similar mean correlations between reading comprehension and the component skills of word reading (M r = 0.65 [0.27-1.03]) and oral language (M r = 0.61 [0.33-0.88]). These findings demonstrate that these skills are essential for reading comprehension in children with ASD, making contributions of similar size. This study advances our understanding of the mechanisms by which children with ASD understand what they read, providing a foundation on which to build programmatic research into each of these mechanisms. LAY SUMMARY: Academic progress is closely tied to children&#039;s ability to understand what they read. Yet reading comprehension is difficult for many children with autism spectrum disorder (ASD). We used a statistical method to summarize existing research on the skills that children with ASD use to understand what they read. We found that the reading comprehension of children with ASD was related to a similar extent to both their ability to read individual words and their oral language skills. These findings suggest that both areas should be assessed in order to determine appropriate interventions to support reading comprehension for children with ASD.
AD  - Sorenson Duncan, Tamara. School of Linguistics and Language Studies, Carleton University, Ottawa, Ontario, Canada.Sorenson Duncan, Tamara. Department of Pediatrics, Dalhousie University &amp; IWK Health Centre, Halifax, Nova Scotia, Canada.Sorenson Duncan, Tamara. Department of Psychology and Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.Karkada, Manasi. Department of Psychology and Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.Deacon, S Helene. Department of Psychology and Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.Smith, Isabel M. Department of Pediatrics, Dalhousie University &amp; IWK Health Centre, Halifax, Nova Scotia, Canada.Smith, Isabel M. Department of Psychology and Neuroscience, Dalhousie University, Halifax, Nova Scotia, Canada.
AN  - 33580639
AU  - Duncan,
AU  - T.
AU  - S.
AU  - Karkada,
AU  - M.
AU  - Deacon,
AU  - S.
AU  - H.
AU  - Smith,
AU  - I.
AU  - M.
DA  - Feb 13
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/aur.2483
DP  - Ovid Technologies
J2  - Autism Res
L1  - internal-pdf://2337455090/Sorenson Duncan-2021.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingFebSorenson Duncan, TamaraKarkada, ManasiDeacon, S HeleneSmith, Isabel M
PY  - 2021
SP  - 13
T2  - Autism research : Official Journal of the International Society for Autism Research
TI  - Building Meaning: Meta-analysis of Component Skills Supporting Reading Comprehension in Children with Autism Spectrum Disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33580639
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33580639&amp;id=doi:10.1002%2Faur.2483&amp;issn=1939-3806&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Autism+research+%3A+Official+Journal+of+the+International+Society+for+Autism+Research&amp;atitle=Building+Meaning%3A+Meta-analysis+of+Component+Skills+Supporting+Reading+Comprehension+in+Children+with+Autism+Spectrum+Disorder.&amp;aulast=Sorenson+Duncan&amp;pid=%3Cauthor%3ESorenson+Duncan+T%3C%2Fauthor%3E%3CAN%3E33580639%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/10.1002/aur.2483
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aur.2483?download=true
VL  - 13
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Given the widespread nature and clinical consequences of self-harm and suicidal ideation among adolescents, establishing the efficacy of developmentally appropriate treatments that reduce both self-harm and suicidal ideation in the context of broader adolescent psychopathology is critical.

**METHODS**: We conducted a systematic review and meta-analysis of the Dialectical Behaviour Therapy for Adolescents (DBT-A) literature on treating self-injury in adolescents (12-19 years). We searched for eligible trials and treatment evaluations published prior to July 2020 in MEDLINE/PubMed, Scopus, Google Scholar, EMBASE, and the Cochrane Library databases for clinical trials. Twenty-one studies were identified [five randomized-controlled trials (RCTs), three controlled clinical trials (CCTs), and 13 pre-post evaluations]. We extracted data for predefined primary (self-harm, suicidal ideation) and secondary outcomes (borderline personality symptoms; BPD) and calculated treatment effects for RCTs/CCTs and pre-post evaluations. This meta-analysis was pre-registered with OSF: osf.io/v83e7.

**RESULTS**: Overall, the studies comprised 1673 adolescents. Compared to control groups, DBT-A showed small to moderate effects for reducing self-harm (g = -0.44; 95% CI -0.81 to -0.07) and suicidal ideation (g = -0.31, 95% CI -0.52 to -0.09). Pre-post evaluations suggested large effects for all outcomes (self-harm: g = -0.98, 95% CI -1.15 to -0.81; suicidal ideation: g = -1.16, 95% CI -1.51 to -0.80; BPD symptoms: g = -0.97, 95% CI -1.31 to -0.63).

**CONCLUSIONS**: DBT-A appears to be a valuable treatment in reducing both adolescent self-harm and suicidal ideation. However, evidence that DBT-A reduces BPD symptoms was only found in pre-post evaluations.
AD  - Kothgassner, Oswald D. Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.Goreis, Andreas. Department of Clinical and Health Psychology, Faculty of Psychology, University of Vienna, Vienna, Austria.Goreis, Andreas. Outpatient Unit for Research, Teaching and Practice, Faculty of Psychology, University of Vienna, Vienna, Austria.Robinson, Kealagh. School of Psychology, Te Herenga Waka - Victoria University of Wellington, Wellington, New Zealand.Huscsava, Mercedes M. Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.Schmahl, Christian. Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.Plener, Paul L. Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.Plener, Paul L. Department of Child and Adolescent Psychiatry and Psychotherapy, University of Ulm, Ulm, Germany.
AN  - 33875025
AU  - Kothgassner,
AU  - O.
AU  - D.
AU  - Goreis,
AU  - A.
AU  - Robinson,
AU  - K.
AU  - Huscsava,
AU  - M.
AU  - M.
AU  - Schmahl,
AU  - C.
AU  - Plener,
AU  - P.
AU  - L.
DA  - Apr 20
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1017/S0033291721001355
DP  - Ovid Technologies
J2  - Psychol Med
L1  - internal-pdf://0405426172/Kothgassner-2021.pdf
LA  - English
N1  - Kothgassner, Oswald DGoreis, AndreasRobinson, KealaghHuscsava, Mercedes MSchmahl, ChristianPlener, Paul L
PY  - 2021
SP  - 1-11
T2  - Psychological Medicine
TI  - Efficacy of dialectical behavior therapy for adolescent self-harm and suicidal ideation: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33875025
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33875025&amp;id=doi:10.1017%2FS0033291721001355&amp;issn=0033-2917&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-11&amp;date=2021&amp;title=Psychological+Medicine&amp;atitle=Efficacy+of+dialectical+behavior+therapy+for+adolescent+self-harm+and+suicidal+ideation%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Kothgassner&amp;pid=%3Cauthor%3EKothgassner+OD%3C%2Fauthor%3E%3CAN%3E33875025%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/800E5FFC241040B62414A8EA25BA2B72/S0033291721001355a.pdf/div-class-title-efficacy-of-dialectical-behavior-therapy-for-adolescent-self-harm-and-suicidal-ideation-a-systematic-review-and-meta-analysis-div.pdf
ER  -
TY  - JOUR
AB  - **Background**
Although widely used, the current evidence for the efficacy of antidepressant and anti-anxiety medications for people with autism spectrum disorder (ASD) is limited and conflicting. 

**Aims**
We carried out a systematic review and meta-analysis of randomised controlled trials that assessed the effectiveness of these medications in people with ASD. Method: We searched the following databases: Cochrane Library, Medline, EMBASE, CINAHL, PsycINFO, ERIC, DARE and ClinicalTrials.gov. Additionally, we hand-searched 11 relevant journals. We used the Cochrane risk-of-bias tool and Jadad score to assess the quality of each included study. We carried out a meta-analysis using a random effects model. 

**Results**
We included 15 randomised controlled trials (13 on antidepressants and two on anti-anxiety medications) for a total of 958 people with ASD. Data showed contradictory findings among the studies, with larger studies mostly showing a non-significant difference in outcomes between the treatment and the placebo groups. Meta-analysis of pooled Yale-Brown Obsessive Compulsive Scale and Clinical Global Impression Scale data from nine studies (60%) did not show any statistically significant inter-group difference on either of the outcome measures. The adverse effects reported were mild and, in most studies, their rates did not show any significant inter-group difference. 

**Conclusions**
Given the methodological flaws in the most included studies and contradictory findings, it is difficult to draw any definitive conclusion about the effectiveness of either antidepressant or anti-anxiety medications to treat either ASD core symptoms or associated behaviours. Robust, large-scale, randomised controlled trials are needed to address this issue. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-91645-001
AU  - Deb,
AU  - S.
AU  - Roy,
AU  - M.
AU  - Lee,
AU  - R.
AU  - Majid,
AU  - M.
AU  - Limbu,
AU  - B.
AU  - Santambrogio,
AU  - J.
AU  - Roy,
AU  - A.
AU  - Bertelli,
AU  - M.
AU  - O.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/bjo.2021.1003
L1  - internal-pdf://1519850679/Deb-2021-Randomised controlled trials of antid.pdf
PY  - 2021
T2  - BJPsych Open Vol 7 2021, ArtID e179
TI  - Randomised controlled trials of antidepressant and anti-anxiety medications for people with autism spectrum disorder: Systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2021-91645-001
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/E3B6397AEA86E4723AE2ADB6E77030DD/S2056472421010036a.pdf/div-class-title-randomised-controlled-trials-of-antidepressant-and-anti-anxiety-medications-for-people-with-autism-spectrum-disorder-systematic-review-and-meta-analysis-div.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - The current meta-analysis comprehensively examined the effects of physical activity interventions on executive function among people with neurodevelopmental disorders. The meta-analysis included 34 studies with 1058 participants aged 5-33 years. Results indicated an overall significant medium effect of physical activity interventions on improving executive function in people with neurodevelopmental disorders under the random-effect model (Hedges&#039; g = 0.56, p &lt;.001). Significant moderators of the effects of physical activity intervention on executive function included age, intervention length and session time, executive function subdomains, and intervention dose (total minutes in the intervention). This meta-analysis provides support for the effectiveness of physical activity interventions on executive function among people with neurodevelopmental disorders. Future studies and limitations are discussed. Copyright &copy; 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
AD  - (Sung, Leung, MacDonald) Adapted Physical Activity, Kinesiology, School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Rm 8 Women&#039;s Building, 160 SW 26th St, Corvallis, OR 97331, United States (Ku) Physical Education and Sports Science Academic Group, National Institute of Education, Nanyang Technological University, Singapore 639798, SingaporeM.-C. Sung, Adapted Physical Activity, Kinesiology, School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Rm 8 Women&#039;s Building, 160 SW 26th St, Corvallis, OR 97331, United States. E-mail: sungmin@oregonstate.edu
AN  - 2011179143
AU  - Sung,
AU  - M.
AU  - C.
AU  - Ku,
AU  - B.
AU  - Leung,
AU  - W.
AU  - MacDonald,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-021-05009-5
DP  - Ovid Technologies
KW  - adhd
KW  - asd
KW  - Cognition
KW  - Disability
KW  - Exercise intervention
KW  - adolescent
KW  - adult
KW  - article
KW  - attention deficit disorder
KW  - child
KW  - controlled study
KW  - executive function
KW  - exercise
KW  - female
KW  - human
KW  - male
KW  - meta analysis
KW  - physical activity
KW  - preschool child
KW  - systematic review
L1  - internal-pdf://0377636650/Sung-2021.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2021
PY  - 2021
T2  - Journal of Autism and Developmental Disorders.
TI  - The Effect of Physical Activity Interventions on Executive Function Among People with Neurodevelopmental Disorders: A Meta-Analysis
UR  - http://www.wkap.nl/journalhome.htm/0162-3257
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2011179143
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33856619&amp;id=doi:10.1007%2Fs10803-021-05009-5&amp;issn=0162-3257&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+Autism+and+Developmental+Disorders&amp;atitle=The+Effect+of+Physical+Activity+Interventions+on+Executive+Function+Among+People+with+Neurodevelopmental+Disorders%3A+A+Meta-Analysis&amp;aulast=Sung&amp;pid=%3Cauthor%3ESung+M.-C.%3C%2Fauthor%3E%3CAN%3E2011179143%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s10803-021-05009-5.pdf
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Whether parental presence during their children&#039;s painful medical procedures is advantageous with regard to child&#039;s pain-related outcomes is questionable. Research regarding this topic is equivocal and additional questions, such as whether levels of parental involvement may play a role as well, remain to be assessed. The purpose of this systematic review is to summarize and critically appraise the literature regarding the impact of parental presence versus absence during their children&#039;s painful medical procedures on the child&#039;s pain-related outcomes. 

**METHODS: **
The review protocol was registered on Prospero (ID CRD42018116614). A systematic search in PubMed, Web of Science, and PsycArticles resulted in 22 eligible studies incorporating 2157 participants. Studies were considered eligible if they included children (&lt;= 18 years old) undergoing a painful medical procedure and compared parental presence and/or involvement with parental absence during the procedure. 

**RESULTS: **
The children&#039;s pain-related outcomes included self-reported pain intensity, self-reported fear, anxiety and distress, observed pain-related behavior, and physiological parameters. Overall, evidence points in the direction of beneficial effects of parental presence versus absence with regard to children&#039;s self-reported pain intensity and physiological parameters, whereas mixed findings were recorded for children&#039;s self-reported fears, anxiety and distress, and observed pain-related behaviors. 

**CONCLUSIONS: **
In order to provide clear recommendations on how to involve the parent during the procedure, as well as for which type of children and parents parental presence has the best effects, further research is needed, as indicated in this review.
AN  - 34453832
AU  - Rheel,
AU  - E.
AU  - Malfliet,
AU  - A.
AU  - Van
AU  - Ryckeghem,
AU  - D.
AU  - M.
AU  - L.
AU  - Pas,
AU  - R.
AU  - Vervoort,
AU  - T.
AU  - Ickmans,
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1093/pm/pnab264
L1  - internal-pdf://2803839882/Rheel-2021-The Impact of Parental Presence on.pdf
PY  - 2021
SP  - 28
T2  - Pain Medicine
TI  - The Impact of Parental Presence on their Children during Painful Medical Procedures:A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34453832
UR  - https://academic.oup.com/painmedicine/advance-article-abstract/doi/10.1093/pm/pnab264/6359192?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/pnab264.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAvgwggL0BgkqhkiG9w0BBwagggLlMIIC4QIBADCCAtoGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM1_ZMwakY4I4BsEdVAgEQgIICq9L42HwhJzqa5zEGxEYd24FSElVRDvfo0UF67rqtAiD5qex0xEN51gYmi-H2pU-jxhgPWTM27_BkTgPAe4eTarlMKECHA5IaWJfTIhFv7ZMr9BwNfSPbMI5hPh1Km-RnnhMVlkHLmkGh4bSKzf0KHHEvX0y3NMgwkz6P7XNqYaSOYbC6aXU8hDsFkYChAILSXDsP4FVy9XeohUGli00Ij7BAFrH8ngJ03B4vKqgt0l8_tYth4WvyJLHlvN3Ev4qKArmBh_GIcE_D5WGhV6azbmDkapokOr3_GTsX1w2ahOA5Kd_B8vOnSE7V-2HQ73FotZdfM_Bf4ifWzfpIPD153FhKb9hBAOmTlHRj7hA9jQY4_su4MzHxUSGZoQ-8qSRgFZDPFNwv4CTRHxOr9nDivgR4wO0jrzIKEwP6cheRSCFI9wNp3hz0hf725WR0IDlbemCcWzjTx4RX7DVk0XFzojJDzLtEh6SmHiLhdFeaoQxT6CKYc009zKmMFVTD7szjWLn-ItQQvcWa5XPAQ8lovIwP88XfJHbc6DfuQ_DfGW11OA5gv_iydFhU-N7h-jFVBUHCDSPzR-UxCDV6RY9HTTdNlHcbbpxeADtxioQ1h179ILvOpk-IHyZ8t0C5n-ri7Mak7s6eUg7_v5obHTnXHC-0BN5ZbhXZ9YcDYQODF10yyLrwcbxXtlID7uH0XwlZaQWHY_Y-fnrAj-VY7IvcMFzlMrBU7pQwafTKaPW6b5tJ7uKJYTWA642v1JgSUaBoDVMrgIBP4ttQchQCaCp-lSrwQhEYeBx2u0OgH9Yo9e_AMw1OOT6FLhREjd63Pm_E8s2bOmc18aPHTGCphl1BsVaZOq5lfrcP75_qIr3xH0Ozn_4X2OAMFBARmrf71M3S_alFnfd07SQLUCTS
VL  - 28
ER  -
TY  - JOUR
AB  - **Background**

This is an update of the review published on the Cochrane Library in 2016, Issue 8. Having cancer may result in extensive emotional, physical and social suffering. Music interventions have been used to alleviate symptoms and treatment side effects in people with cancer. This review includes music interventions defined as music therapy offered by trained music therapists, as well as music medicine, which was defined as listening to pre‐recorded music offered by medical staff. 

**Objectives**
To assess and compare the effects of music therapy and music medicine interventions for psychological and physical outcomes in people with cancer. 

**Search methods**
We searched the Cochrane Central Register of Controlled Trials (CENTRAL; 2020, Issue 3) in the Cochrane Library, MEDLINE via Ovid, Embase via Ovid, CINAHL, PsycINFO, LILACS, Science Citation Index, CancerLit, CAIRSS, Proquest Digital Dissertations, ClinicalTrials.gov, Current Controlled Trials, the RILM Abstracts of Music Literature, http://www.wfmt.info/Musictherapyworld/ and the National Research Register. We searched all databases, except for the last two, from their inception to April 2020; the other two are no longer functional, so we searched them until their termination date. We handsearched music therapy journals, reviewed reference lists and contacted experts. There was no language restriction. Selection criteria We included all randomized and quasi‐randomized controlled trials of music interventions for improving psychological and physical outcomes in adults and pediatric patients with cancer. We excluded patients undergoing biopsy and aspiration for diagnostic purposes. 

**Data collection and analysis**
Two review authors independently extracted the data and assessed the risk of bias. Where possible, we presented results in meta‐analyses using mean differences and standardized mean differences. We used post‐test scores. In cases of significant baseline difference, we used change scores. We conducted separate meta‐analyses for studies with adult participants and those with pediatric participants. Primary outcomes of interest included psychological outcomes and physical symptoms and secondary outcomes included physiological responses, physical functioning, anesthetic and analgesic intake, length of hospitalization, social and spiritual support, communication, and quality of life (QoL) . We used GRADE to assess the certainty of the evidence. Main results We identified 29 new trials for inclusion in this update. In total, the evidence of this review rests on 81 trials with a total of 5576 participants. Of the 81 trials, 74 trials included adult (N = 5306) and seven trials included pediatric (N = 270) oncology patients. We categorized 38 trials as music therapy trials and 43 as music medicine trials. The interventions were compared to standard care. 

**Psychological outcomes**

 The results suggest that music interventions may have a large anxiety‐reducing effect in adults with cancer, with a reported average anxiety reduction of 7.73 units (17 studies, 1381 participants; 95% confidence interval (CI) ‐10.02 to ‐5.44; very low‐certainty evidence) on the Spielberger State Anxiety Inventory scale (range 20 to 80; lower values reflect lower anxiety). Results also suggested a moderately strong, positive impact of music interventions on depression in adults (12 studies, 1021 participants; standardized mean difference (SMD): &minus;0.41, 95% CI &minus;0.67 to &minus;0.15; very low‐certainty evidence). We found no support for an effect of music interventions on mood (SMD 0.47, 95% CI &minus;0.02 to 0.97; 5 studies, 236 participants; very low‐certainty evidence). Music interventions may increase hope in adults with cancer, with a reported average increase of 3.19 units (95% CI 0.12 to 6.25) on the Herth Hope Index (range 12 to 48; higher scores reflect greater hope), but this finding was based on only two studies (N = 53 participants; very low‐certainty evidence). 

**Physical outcomes**

We found a moderate pain‐reducing effect of music interventions (SMD &minus;0. 7, 95% CI &minus;1.07 to &minus;0.26; 12 studies, 632 adult participants; very low‐certainty evidence). In addition, music interventions had a small treatment effect on fatigue (SMD &minus;0.28, 95% CI &minus;0.46 to &minus;0.10; 10 studies, 498 adult participants; low‐certainty evidence). The results suggest a large effect of music interventions on adult participants&#039; QoL, but the results were highly inconsistent across studies, and the pooled effect size was accompanied by a large confidence interval (SMD 0.88, 95% CI &minus;0.31 to 2.08; 7 studies, 573 participants; evidence is very uncertain). Removal of studies that used improper randomization methods resulted in a moderate effect size that was less heterogeneous (SMD 0.47, 95% CI 0.06 to 0.88, P = 0.02, I 2 = 56%). A small number of trials included pediatric oncology participants. The findings suggest that music interventions may reduce anxiety but this finding was based on only two studies (SMD &minus;0.94, 95% CI &minus;1.9 to 0.03; very low‐certainty evidence). Due to the small number of studies, we could not draw conclusions regarding the effects of music interventions on mood, depression, QoL, fatigue or pain in pediatric participants with cancer. The majority of studies included in this review update presented a high risk of bias, and therefore the overall certainty of the evidence is low. For several outcomes (i.e. anxiety, depression, pain, fatigue, and QoL) the beneficial treatment effects were consistent across studies for music therapy interventions delivered by music therapists. In contrast, music medicine interventions resulted in inconsistent treatment effects across studies for these outcomes. 

**Authors&#039; conclusions**
This systematic review indicates that music interventions compared to standard care may have beneficial effects on anxiety, depression, hope, pain, and fatigue in adults with cancer. The results of two trials suggest that music interventions may have a beneficial effect on anxiety in children with cancer. Too few trials with pediatric participants were included to draw conclusions about the treatment benefits of music for other outcomes. For several outcomes, music therapy interventions delivered by a trained music therapist led to consistent results across studies and this was not the case for music medicine interventions. Moreover, evidence of effect was found for music therapy interventions for QoL and fatigue but not for music medicine interventions. Most trials were at high risk of bias and low or very low certainty of evidence; therefore, these results need to be interpreted with caution. 

**Plain language summary**
Can music interventions benefit people with cancer? 

**The issue**
Cancer may result in extensive emotional, physical and social suffering. Music therapy and music medicine interventions have been used to alleviate symptoms and treatment side effects and address psychosocial needs in people with cancer. In music medicine interventions, patients simply listen to pre‐recorded music that is offered by a medical professional. Music therapy requires the implementation of a music intervention by a trained music therapist, the presence of a therapeutic process and the use of personally tailored music experiences. 

**The aim of the review**
This review is an update of a previous Cochrane review from 2016, which included 52 studies. For this review update, we searched for additional trials studying the effect of music interventions on psychological and physical outcomes in people with cancer. We searched for studies up to April 2020. 

**What are the main findings?**
We identified 29 new studies, so the evidence in this review update now rests on 81 studies with 5576 participants. Of the 81 studies, 74 trials included adults and 7 included children.The findings suggest that music therapy and music medicine interventions may have a beneficial effect on anxiety, depression, hope, pain, fatigue, heart rate and blood pressure in adults with cancer. Music therapy but not music medicine interventions may improve adult patients&#039; quality of life and levels of fatigue. We did not find evidence that music interventions improve mood, distress or physical functioning, but only a few trials studied these outcomes. We could not draw any conclusions about the effect of music interventions on immunologic functioning, resilience, spiritual well‐being or communication outcomes in adults because there were not enough trials looking at these aspects. Due to the small number of trials, we could not draw conclusions for children. Therefore, more research is needed. Overall, the treatment benefits of music therapy interventions were more consistent across trials than those of music medicine interventions, leading to greater confidence in the treatment impact of music therapy interventions delivered by a trained music therapist. No adverse effects of music interventions were reported. 

**Quality of the evidence**
Most trials were at high risk of bias, so these results need to be interpreted with caution. We did not identify any conflicts of interests in the included studies. 

**What are the conclusions?**
We conclude that music interventions may have beneficial effects on anxiety, depression, hope, pain, and fatigue in adults with cancer. Furthermore, music may have a small positive effect on heart rate and blood pressure. Reduction of anxiety, depression, fatigue and pain are important outcomes for people with cancer, as they have an impact on health and overall quality of life.
AN  - CD006911
AU  - Bradt,
AU  - J.
AU  - Dileo,
AU  - C.
AU  - Myers-Coffman,
AU  - K.
AU  - Biondo,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD006911.pub4
KW  - Affect
KW  - Anxiety [*therapy]
KW  - Body Image
KW  - Depression [therapy]
KW  - Fatigue [therapy]
KW  - Humans
KW  - Music Therapy [*methods]
KW  - Music [psychology]
KW  - Neoplasms [physiopathology, *psychology]
KW  - Pain Management
KW  - Quality of Life
KW  - Standard of Care
KW  - Stress, Psychological [therapy]
KW  - Treatment Outcome
N1  - [Gynaecological, Neuro-oncology and Orphan Cancer]
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - Music interventions for improving psychological and physical outcomes in people with cancer
UR  - http://dx.doi.org/10.1002/14651858.CD006911.pub4
ER  -
TY  - JOUR
AB  - Developed by Siegfried (&quot;Zig&quot;) Engelmann and colleagues, direct instruction (DI) has been recognized as an effective and replicable teaching model for decades. Although rooted in many principles of learning that behavior analysts utilize in daily practice, DI is not a common a component of behavior analytic services for learners with autism spectrum disorder (ASD). This may be attributed to behavior analysts&#039; unfamiliarity with research evaluating the efficacy of DI with learners with ASD. This article synthesizes findings across studies evaluating DI with learners with ASD. The review addresses the contributions of the studies to date and identifies additional areas of research that may lead to more learners with ASD benefitting from DI.
AN  - WOS:000656758000001
AU  - Frampton,
AU  - S.
AU  - E.
AU  - Munk,
AU  - G.
AU  - T.
AU  - Shillingsburg,
AU  - L.
AU  - A.
AU  - Shillingsburg,
AU  - M.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40614-021-00292-0
L1  - internal-pdf://1441110002/Frampton-A Systematic Review and Quality Appra.pdf
PY  - 2021
SP  - 22
T2  - Perspectives on Behavior Science
TI  - A Systematic Review and Quality Appraisal of Applications of Direct Instruction with Children with Autism Spectrum Disorder
UR  - &lt;Go to ISI&gt;://WOS:000656758000001
UR  - https://link.springer.com/content/pdf/10.1007/s40614-021-00292-0.pdf
ER  -
TY  - JOUR
AB  - In recent years a large array of treatment protocols conceptualized as transdiagnostic have been developed with clinical and practical advantages compared to traditional single-disorder protocols. Within this panorama, the Transdiagnostic Unified Protocol (UP) of Emotional Disorders was developed aimed at treating the negative affective processes underlying several diagnostic categories, and accounting for the covariance of different emotional disorders. The UP has been found to efficiently target the roots of these disorders leading to a reduction in symptoms of co-occurring disorders. However, several questions have marginally addressed in the previous studies, and some UP features still remain unexplored. 

The present meta-analysis aims at evaluating whether the UP results to significant changes in anxiety and depression symptoms severity in children, adolescents, and adults. 19 RCTs and 13 uncontrolled pre-post trials comprising 2183 patients/clients met inclusion criteria for meta-analysis. Large to moderate combined overall effect size for both depression plus anxiety were detected in the uncontrolled pre-post studies (g = 0.756) and in RTCs studies (g = 0.452), respectively. Large effect size at pre-treatment to 3-6-month follow-up was observed for combined depression plus anxiety (g = 1.113). Subgroup analysis suggested that UP treatment does not differ across the anxiety and depression self-report measures. Moreover, UP intervention outperformed both passive and active control conditions to treat negative affective syndromes. Meta-regression confirmed the moderate effects of therapist level of experience, the sample characteristics, and the UP-protocol adaptations. 

The findings indicate that the manualized UP treatment has potential to contribute to improving mental health outcomes, particularly of anxiety and depression. Copyright &copy; 2021 Elsevier Ltd
AN  - 2012751982
AU  - Carlucci,
AU  - L.
AU  - Saggino,
AU  - A.
AU  - Balsamo,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.cpr.2021.101999
L1  - internal-pdf://1652583377/Carlucci-2021-On the efficacy of the unified p.pdf
PY  - 2021
T2  - Clinical Psychology Review
TI  - On the efficacy of the unified protocol for transdiagnostic treatment of emotional disorders: A systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/clinpsychrev
VL  - 87 (no pagination)
ER  -
TY  - JOUR
AB  - **Background:** 
Attention-deficit hyperactivity disorder (ADHD) is a commonly diagnosed behavioral disorder in school-aged children. A core symptom of ADHD is difficulties with executive functions (EF). Physical activity (PA) interventions are proposed to be a valuable addition to traditional treatment approaches for ADHD. This systematic review examined the evidence for the effect of chronic PA on EF, specifically, inhibition, shifting, working memory, and attention in children with ADHD compared to no treatment. The moderating impact of PA cognitive demand and methylphenidate (MPH) treatment on the effect of PA interventions on EF was also examined. 

**Method(s):** 
A systematic review and meta-analyses were conducted following the Cochrane Guidelines for Systematic Reviews. A protocol was published with PROSPERO (CRD42018099617); seven databases were searched, and 3690 results screened by two independent researchers. Based on inclusion and exclusion criteria, 12 eligible studies were included, and separate meta-analyses were conducted for each EF domain, each including subgroups of high vs low cognitive demand, and MPH-intake vs. MPH-free. 

**Result(s):** 
Results showed beneficial effects of PA for all EF, with 95%-CI compatible with positive effects for shifting (SMD = -1.58; 95%-CI [-3.12; -0.04]) and working memory (SMD = -0.99; 95%-CI [-1.80; -0.18])only. Cognitive demand of PA differed in its impact depending on the domain of EF. Benefits of PA were lesser in those taking MPH, though subgroup differences were statistically non-significant. 

**Conclusion(s):** 
Children with ADHD benefit from PA leading to enhanced executive functioning performance. However, the cognitive demands of the PA need to be considered when contemplating PA as an adjunctive treatment option. Copyright &copy; 2020 Elsevier Ltd
AD  - (Welsch, Kelly, Fawkner, Booth, Niven) University of Edinburgh, Moray House School of Education and Sport, University of Edinburgh (Holyrood Campus), Scotland EH8 8AQ, United Kingdom (Alliott) MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, England, Cambridge CB2 0QQ, United Kingdom (Kelly, Fawkner, Niven) Physical Activity for Health Research Center, Moray House School of Education and Sport, St Leonard&#039;s Land, University of Edinburgh EH8 8AQ, United KingdomL. Welsch, University of Edinburgh, Moray House School of Education and Sport, University of Edinburgh (Holyrood Campus), Scotland EH8 8AQ, United Kingdom. E-mail: livia.welsch@institut-fuer-ppt.de
AN  - 2010596329
AU  - Welsch,
AU  - L.
AU  - Alliott,
AU  - O.
AU  - Kelly,
AU  - P.
AU  - Fawkner,
AU  - S.
AU  - Booth,
AU  - J.
AU  - Niven,
AU  - A.
DA  - Januar
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.mhpa.2020.100379
DP  - Ovid Technologies
KW  - adhd
KW  - Attention
KW  - Exercise therapy
KW  - Inhibition
KW  - Shifting
KW  - Working memory
KW  - article
KW  - attention deficit disorder
KW  - child
KW  - executive function
KW  - female
KW  - human
KW  - kinesiotherapy
KW  - male
KW  - meta analysis
KW  - physical activity
KW  - practice guideline
KW  - systematic review
KW  - methylphenidate
L1  - internal-pdf://2547299076/Welsch-2021.pdf
LA  - English
PY  - 2021
T2  - Mental Health and Physical Activity
TI  - The effect of physical activity interventions on executive functions in children with ADHD: A systematic review and meta-analysis
UR  - http://www.elsevier.com
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010596329
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.mhpa.2020.100379&amp;issn=1755-2966&amp;isbn=&amp;volume=20&amp;issue=&amp;spage=100379&amp;pages=&amp;date=2021&amp;title=Mental+Health+and+Physical+Activity&amp;atitle=The+effect+of+physical+activity+interventions+on+executive+functions+in+children+with+ADHD%3A+A+systematic+review+and+meta-analysis&amp;aulast=Welsch&amp;pid=%3Cauthor%3EWelsch+L.%3C%2Fauthor%3E%3CAN%3E2010596329%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/abs/pii/S1755296620300636?via%3Dihub
VL  - 20 (no pagination)
ER  -
TY  - JOUR
AB  - **CONTEXT**: Children who receive more responsive care during their early childhood tend to exhibit stronger cognitive development, mental well-being, and physical health across their life course. 

**OBJECTIVE**: Determine how to design effective responsivity training programs for caregivers. 

**DATA SOURCES**: We searched seven electronic databases through October 2020. STUDY SELECTION: Randomized trials (k = 120) of programs training parents of children ages 0 to 6 to be more responsive. DATA EXTRACTION: Two reviewers independently extracted data. Data were pooled by using random-effects pairwise and network meta-analyses. 

**RESULTS**: Programs had, on average, a medium effect (d = 0.56; 95% confidence interval [CI]: 0.47 to 0.65). The most effective programs included didactic teaching and opportunities for parents to observe models, practice skills, and receive feedback (d = 1.07; 95% CI: 0.37 to 1.77), or all these instructional methods in addition to reflection (d = 0.86; 95% CI: 0.64 to 1.09). Programs that had participants observe examples of responsivity (d = 0.70; 95% CI: 0.57 to 0.83), used researchers as facilitators (d = 0.89; 95% CI: 0.66 to 1.12), assigned homework (d = 0.85; 95% CI: 0.66 to 1.02), and had a narrow scope (d = 0.72; 95% CI: 0.57 to 0.87) were more effective than those that did not. LIMITATIONS: Most samples included only mothers from Western countries and lacked follow-up data. 

**CONCLUSIONS**: Having parents observe examples of responsive caregiving and complete home-practice in short, focused programs may be an effective, scalable approach to enhancing responsivity in the general population and reducing inequalities in child development.
AN  - 34261810
AU  - Sokolovic,
AU  - N.
AU  - Rodrigues,
AU  - M.
AU  - Tricco,
AU  - A.
AU  - C.
AU  - Dobrina,
AU  - R.
AU  - Jenkins,
AU  - J.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1542/peds.2020-033563
L1  - internal-pdf://1671291044/Sokolovic-2021-Teaching Parents to Be Responsi.pdf
PY  - 2021
T2  - Pediatrics
TI  - Teaching Parents to Be Responsive: A Network Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34261810
UR  - https://pediatrics.aappublications.org/content/148/2/e2020033563
UR  - https://pediatrics.aappublications.org/content/pediatrics/148/2/e2020033563.full.pdf
VL  - 148
ER  -
TY  - JOUR
AB  - A meta-analysis update of randomized controlled trials investigating recombinant human erythropoietin suggests improved neurodevelopmental outcome in preterm infants. There was substantial heterogeneity, which could be ascribed to a single trial. Exclusion of this trial featuring a high risk of bias abolished heterogeneity and any effects of recombinant human erythropoietin treatment.
AN  - 34095027
AU  - Fischer,
AU  - H.
AU  - S.
AU  - Reibel,
AU  - N.
AU  - J.
AU  - Buhrer,
AU  - C.
AU  - Dame,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fped.2021.657228
L1  - internal-pdf://1720554241/Fischer-2021-Prophylactic Erythropoietin for N.pdf
PY  - 2021
SP  - 657228
T2  - Frontiers in Pediatrics
TI  - Prophylactic Erythropoietin for Neuroprotection in Very Preterm Infants: A Meta-Analysis Update
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34095027
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173165/pdf/fped-09-657228.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - **Background**: Cannabis is one of the most used drugs worldwide. There is no gold standard treatment for cannabis use disorder (CUD). Motivational interviewing (MI) has shown efficacy in some substance use disorders. 

Therefore, a systematic review was conducted to assess the effectiveness of MI in CUD. Methods: Randomized controlled trials or open-label studies published until September 2019 from 3 different databases (Pubmed, Scopus, and PsycINFO) were included, following the PRISMA guidelines and a predetermined set of criteria for article selection. Meta-analyses were conducted. The end point was determined as month 3, and 4 outcomes were analysed (abstinence rates, reduction in frequency of use, reduction in quantity of use, and reduction in cannabis use disorder symptoms) in 2 populations (adolescents and adults). 

**Results**: Forty studies were identified, of which 24 were performed in adults and 16 in adolescents. MI showed efficacy in achieving abstinence in both adults (odds ratio [OR] = 3.84, 95% confidence interval [CI] 2.40-6.16, p &lt; 0.0001) and adolescents (OR = 2.02, 95% CI 1.42-2.89, p &lt; 0.0001). MI showed efficacy in reducing frequency and quantity of use in adults but not in adolescents. Those adults who were in the MI group consumed less joints per day than those in the control group (mean difference = -0.69 joints per day, 95% CI -0.84 to -0.53, p &lt; 0.001), and they consumed on less days per month (mean difference = -3.9 days per month, 95% CI -7.47 to -0.34, p = 0.0317) than those in the control group. 

**Conclusions**: MI is an effective intervention to reduce cannabis use and achieve abstinence, especially among adults and patients with no prior history of psychotic disorder. Further investigation is needed to assess the effect on CUD symptoms. MI should be included in guidelines for treating cannabis use disorder as one of the essential psychological interventions.
AN  - WOS:000652272700001
AU  - Calomarde-Gomez,
AU  - C.
AU  - Jimenez-Fernandez,
AU  - B.
AU  - Balcells-Olivero,
AU  - M.
AU  - Gual,
AU  - A.
AU  - Lopez-Pelayo,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1159/000515667
L1  - internal-pdf://1545942657/Calomarde-Gomez.pdf
PY  - 2021
T2  - EUROPEAN ADDICTION RESEARCH
TI  - Motivational Interviewing for Cannabis Use Disorders: A Systematic Review and Meta-Analysis
UR  - https://www.karger.com/Article/Abstract/515667
UR  - https://www.karger.com/Article/Pdf/515667
ER  -
TY  - JOUR
AB  - **Background**: Primary prevention has the potential to modify the course of depression, but the consistency and magnitude of this effect are currently undetermined. 

**Method(s)**: PRISMA and RIGHT compliant (PROSPERO:CRD42020179659) systematic meta-review, PubMed/Web of Science, up to June 2020. Meta-analyses of controlled interventions for the primary prevention of depressive symptoms [effect measures: standardized mean difference (SMD)] or depressive disorders [effect measure: relative risk (RR)] were carried out. Results were stratified by: (i) age range; (ii) target population (general and/or at-risk); (iii) intervention type. Quality (assessed with AMSTAR/AMSTAR-PLUS content) and credibility (graded as high/moderate/low) were assessed. USPSTF grading system was used for recommendations. 

**Result(s)**: Forty-six meta-analyses (k=928 individual studies, n=286,429 individuals, mean age=22.4 years, 81.1% female) were included. Effect sizes were: SMD=0.08-0.53; for depressive symptoms; RR=0.90-0.28 for depressive disorders. Sensitivity analyses including only RCTs did not impact the findings. AMSTAR median=9 (IQR=8-9); AMSTAR-PLUS content median=4.25 (IQR=4-5). Credibility of the evidence was insufficient/low in 43 (93.5%) meta-analyses, moderate in two (4.3%), and high in one (2.2%): reduction of depressive symptoms using psychosocial interventions for young adults only, and a combination of psychological and educational interventions in primary care had moderate credibility; preventive administration of selective serotonin reuptake inhibitors (SSRIs) for depressive disorders in individuals with a stroke had high credibility. Limitation(s): Intervention heterogeneity and lack of long-term efficacy evaluation. 

**Conclusion(s)**: Primary preventive interventions for depression might be effective. Among them, clinicians may offer SSRIs post-stroke to prevent depressive disorders, and psychosocial interventions for children/adolescents/young adults with risk factors or during the prenatal/perinatal period. Copyright &copy; 2021 The Authors
AN  - 2013972629
AU  - Salazar
AU  - de
AU  - Pablo,
AU  - G.
AU  - Solmi,
AU  - M.
AU  - Vaquerizo-Serrano,
AU  - J.
AU  - Radua,
AU  - J.
AU  - Passina,
AU  - A.
AU  - Morsillo,
AU  - P.
AU  - Correll,
AU  - C.
AU  - U.
AU  - Borgwardt,
AU  - S.
AU  - Galderisi,
AU  - S.
AU  - Bechdolf,
AU  - A.
AU  - Pfennig,
AU  - A.
AU  - Bauer,
AU  - M.
AU  - Kessing,
AU  - L.
AU  - V.
AU  - van
AU  - Amelsvoort,
AU  - T.
AU  - Nieman,
AU  - D.
AU  - H.
AU  - Domschke,
AU  - K.
AU  - Krebs,
AU  - M.
AU  - O.
AU  - Sand,
AU  - M.
AU  - Vieta,
AU  - E.
AU  - McGuire,
AU  - P.
AU  - Arango,
AU  - C.
AU  - Shin,
AU  - J.
AU  - I.
AU  - Fusar-Poli,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2021.07.101
L1  - internal-pdf://3304737523/Salazar de Pabl-2021-Primary prevention of dep.pdf
N1  - Ingrid Borren (2021-09-15 21:10:59)(Screen): ungdom?;
PY  - 2021
SP  - 957-970
T2  - Journal of Affective Disorders
TI  - Primary prevention of depression: An umbrella review of controlled interventions
UR  - http://www.elsevier.com/locate/jad
VL  - 294
ER  -
TY  - GEN
AB  - Tom verdi
AU  - Ames,
AU  - H.
AU  - M.
AU  - R.
AU  - Muller,
AU  - A.
AU  - E.
AU  - Jardim,
AU  - P.
AU  - S.
AU  - J.
AU  - Langøien,
AU  - L.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - Tom verdi
PY  - 2021
TI  - Effekter av og erfaringer med eksterne skolefokuserte tiltak for barn og unge som er plassert på barnevernsinstitusjon: En mixed-methods systematisk oversikt
UR  - https://www.fhi.no/publ/2021/effekter-av-og-erfaringer-med-eksterne-skolefokuserte-tiltak-for-barn-og-un/
ER  -
TY  - JOUR
AB  - Cognitive behavioral therapy (CBT) is a well-established treatment for anxiety disorders. However, few efforts have been made to summarize the impact of specific intervention-related variables on therapeutic outcomes in different-aged youth with a separation anxiety disorder (SAD). 

PRISMA guidelines were followed to provide an efficacy overview of different disorder-specific CBT protocols against transdiagnostic ones among youth with SAD. Literature search was conducted in Pubmed, EBSCOhost, PsychInfo, PsycArticles, PSYNDEX, Medline, and ERIC. 

In total, 9 papers met the eligibility criteria. Overall, preschoolers benefited more from disorder-specific CBT protocols, whereas school-aged children and adolescents from transdiagnostic ones. Interventions aimed at removing SAD maintenance factors, by including parent-sessions, were efficacious, especially among younger children. Psychotherapy had higher efficacy than drug treatments, with individual- and group-CBT addressing SAD symptoms similarly. Findings support CBT as the golden standard for SAD in youth, impacting on the core symptoms in a time-limited, goal-directed way, with long-term effects.Y
AN  - WOS:000723555300001
AU  - Giani,
AU  - L.
AU  - Caputi,
AU  - M.
AU  - Forresi,
AU  - B.
AU  - Michelini,
AU  - G.
AU  - Scaini,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s41811-021-00129-3
L1  - internal-pdf://4092140648/Giani-Evaluation of Cognitive-Behavioral Thera.pdf
PY  - 2021
SP  - 24
T2  - International Journal of Cognitive Therapy
TI  - Evaluation of Cognitive-Behavioral Therapy Efficacy in the Treatment of Separation Anxiety Disorder in Childhood and Adolescence: a Systematic Review of Randomized Controlled Trials
UR  - &lt;Go to ISI&gt;://WOS:000723555300001
UR  - https://link.springer.com/content/pdf/10.1007/s41811-021-00129-3.pdf
ER  -
TY  - JOUR
AB  - Sammanfattning
Bakgrund och syfte
I den h&auml;r rapporten utv&auml;rderar vi program f&ouml;r att f&ouml;rebygga psykisk oh&auml;lsa hos barn upp till 18 års ålder. Med program avser vi standardiserade manualbaserade insatser som syftar till att påverka ett beteende eller ett tillstånd. Rapporten t&auml;cker program som f&ouml;rmedlas till barnet sj&auml;lvt i skolan eller som ges till f&ouml;r&auml;ldrarna eller hela familjen.

Vi har avgr&auml;nsat psykisk oh&auml;lsa till dels utagerande dels inåtv&auml;nda problem och beteenden. Till utagerande beteenden h&ouml;r aggressivitet och st&ouml;rande uppf&ouml;rande. Vi avgr&auml;nsade inåtv&auml;nda problem till ångest och depressivitet. Kortsiktiga mål f&ouml;r den h&auml;r typen av program &auml;r att minska nivån av problem på gruppnivå. Långsiktiga mål &auml;r att f&ouml;rebygga svåra problem och diagnoser som normbrytande beteenden, uppf&ouml;randest&ouml;rning, ångest och depression och att minska risken f&ouml;r långsiktiga konsekvenser av psykisk oh&auml;lsa som till exempel kriminalitet, våld och suicid.

F&ouml;r att ett program skulle ses som f&ouml;rebyggande kr&auml;vde vi att effekterna f&ouml;ljdes upp efter minst sex månader, i enlighet med internationella riktlinjer.

F&ouml;rebyggande program kan ges på flera nivåer. Universella program f&ouml;rmedlas brett, till exempel till hela skolor medan selektiva program erbjuds till grupper av barn som på gruppnivå har en f&ouml;rh&ouml;jd risk f&ouml;r psykisk oh&auml;lsa. Indikerade program ges riktat till barn som visar tidiga tecken på psykisk oh&auml;lsa. Studier d&auml;r barnen uppfyllde kriterier på en diagnos och d&auml;r målet var att snabbt få en f&ouml;rb&auml;ttring, det vill s&auml;ga snarast behandling, ingick inte i utv&auml;rderingen.

Syftet med projektet var att uppdatera en tidigare SBU-rapport från år 2010 om program f&ouml;r att f&ouml;rebygga psykisk oh&auml;lsa hos barn. Uppdateringen &auml;r en del av ett regeringsuppdrag om psykisk h&auml;lsa bland barn och unga (S2020/01043/FS). Rapporten består av systematiska &ouml;versikter om programmens effekter och risker, de erfarenheter som finns av programmen och deras kostnadseffektivitet samt en diskussion om etiska och sociala aspekter på anv&auml;ndningen av program.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2021
TI  - Program f&ouml;r att f&ouml;rebygga psykisk oh&auml;lsa hos barn: En systematisk &ouml;versikt och utv&auml;rdering av medicinska, h&auml;lsoekonomiska/ekonomiska, sociala och etiska aspekter
UR  - https://www.sbu.se/sv/publikationer/SBU-utvarderar/program-for-att-forebygga-psykisk-ohalsa-hos-barn2/
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Previous studies found that exercise interventions have positive effects on executive functions of the general population. However, studies seldom target executive functions of children and adolescents with attention-deficit hyperactivity disorder (ADHD). This study aimed to synthesise empirical studies regarding the effects of exercise interventions on executive functions of children and adolescents with ADHD.

**METHODS**: A systematic search of the relevant literature was conducted in March 2020 through six electronic databases: CINAHL Complete, Eric, MEDLINE, PsychINFO, SPORTDiscus with Full Text, and Web of Science. Randomised controlled trials/quasi-experimental designs that applied exercise interventions and assessed executive functions through neurocognitive tasks among children and adolescents with ADHD were included. Altogether, 314 studies were identified, from which 31 full texts were independently assessed by two authors for eligibility. Finally, 21 studies underwent systematic reviews and 15 were selected for meta-analysis. Data extraction procedures and risk of bias analysis were conducted by two independent authors using the Physiotherapy Evidence Database (PEDro) scale.

**RESULTS**: The findings indicated that exercise interventions improved overall executive functions of children and adolescents with ADHD (SMD = 0.611, 95% CI [0.386 to 0.836], p &lt; 0.01). Exercise interventions had a moderate-to-large positive effect on inhibitory control (g = 0.761, 95% CI [0.376 to 1.146], p &lt; 0.01) and cognitive flexibility (g = 0.780, 95% CI [0.331 to 1.228], p &lt; 0.001). Likewise, during the subgroup analysis, intervention intensity and sessions of exercise (acute vs chronic) significantly moderated exercise intervention rather than intervention type.

**CONCLUSIONS**: Chronic sessions of exercise interventions with moderate intensity should be incorporated as treatment for children with ADHD to promote executive functions.
AD  - Liang, Xiao. Department of Sports Science and Physical Education, The Chines University of Hong Kong, Shatin, New Territories, Hong Kong, China.Li, Ru. Faculty of Physical Education, Shenzhen University, Shenzhen, China.Wong, Stephen H S. Department of Sports Science and Physical Education, The Chines University of Hong Kong, Shatin, New Territories, Hong Kong, China.Sum, Raymond K W. Department of Sports Science and Physical Education, The Chines University of Hong Kong, Shatin, New Territories, Hong Kong, China.Sit, Cindy H P. Department of Sports Science and Physical Education, The Chines University of Hong Kong, Shatin, New Territories, Hong Kong, China. sithp@cuhk.edu.hk.
AN  - 34022908
AU  - Liang,
AU  - X.
AU  - Li,
AU  - R.
AU  - Wong,
AU  - S.
AU  - H.
AU  - S.
AU  - Sum,
AU  - R.
AU  - K.
AU  - W.
AU  - Sit,
AU  - C.
AU  - H.
AU  - P.
DA  - May 22
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12966-021-01135-6
DP  - Ovid Technologies
J2  - Int
L1  - internal-pdf://1455837329/Liang-2021.pdf
LA  - English
M3  - Review
N1  - Liang, XiaoLi, RuWong, Stephen H SSum, Raymond K WSit, Cindy H P
PY  - 2021
SP  - 68
T2  - International Journal of Behavioral Nutrition &amp; Physical Activity
TI  - The impact of exercise interventions concerning executive functions of children and adolescents with attention-deficit/hyperactive disorder: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34022908
UR  - https://ijbnpa.biomedcentral.com/track/pdf/10.1186/s12966-021-01135-6.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - **Objectives**This meta-review integrates the findings of meta-analyses and systematic reviews to explore the effect of intervention programs on recidivism for juvenile offenders.

**Methods**The systematic literature search gathered 48 meta-analyses and systematic reviews from 53 research reports, contributing 56 independent effect sizes for analysis. These effect sizes were statistically integrated, and five moderators of theoretical and methodological importance were tested using meta-regression.

**Results** On average, intervention programs are associated with a significant reduction in recidivism (rPHI = -0.09, p &lt; 0.001) for juvenile offenders who participate in a program compared to those who do not. However, reductions in recidivism significantly vary between the levels of criminal justice system, characteristics of juvenile offenders, types of program modalities, and methodological quality.

**Conclusions** Results indicate that intervention programs can be an effective approach to reducing recidivism for juvenile offenders, especially when combined with a rehabilitative program modality. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-56968-001
AU  - Pappas,
AU  - Lacee
AU  - N.
AU  - Dent,
AU  - Amy
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s11292-021-09472-z
L1  - internal-pdf://3391801198/Pappas-2021-The 40-year debate_ A meta-review.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Journal of Experimental Criminology
TI  - The 40-year debate: A meta-review on what works for juvenile offenders
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-56968-001
UR  - https://link.springer.com/content/pdf/10.1007/s11292-021-09472-z.pdf
ER  -
TY  - JOUR
AB  - **Background**: Digital health interventions might extend service provisions for youth with chronic medical conditions (CC) and comorbid mental health symptoms. We aimed to comprehensively evaluate the efficacy of Internet- and mobile-based interventions (IMIs) for different psychological and disease-related outcomes in children and adolescents with CC. 

**Method(s)**: Studies were identified by systematic searches in CENTRAL, Embase, MEDLINE/PubMed and PsycINFO, complemented by searches in reference lists of eligible studies and other reviews. We included studies, when they were randomized controlled trials (RCTs) comparing the efficacy of an IMI to control conditions in improving psychological and disease-related outcomes in youth (mean age &lt;= 18 years) with CC. Study selection, data extraction and risk of bias assessment were conducted independently by two reviewers. Meta-analyses were performed within a random-effects model, and Hedges&#039; g (with 95% confidence intervals) was calculated as effect size measure. Primary outcomes were comorbid mental health symptoms (i.e., depression, anxiety and stress), as well as quality of life and self-efficacy. 

**Result(s)**: A total of 19 randomized controlled trials (2410 patients) were included in this meta-analysis. IMIs were associated with improvements in self-efficacy (g = 0.38; 95% CI, 0.15 to 0.61; I&lt;sup&gt;2&lt;/sup&gt; = 0) and combined disease-related outcomes (g = -0.13; 95% CI, -0.25 to -0.01; I&lt;sup&gt;2&lt;/sup&gt; = 21). Meta-analyses on other outcomes were non-significant, and some pre-planned analyses were not feasible because of a shortage of studies. 

**Conclusion(s)**: The available evidence on IMIs for improving mental and health-related outcomes in youth with CC is limited. Our findings point to a rather small benefit and limited efficacy. Future research is needed, to comprehensively assess the potential of IMIs to extend collaborative care, and to identify factors contributing to improved user-centered interventions with better treatment outcomes. Copyright &copy; 2021 The Authors
AD  - (Domhardt, Schroder, Geirhos, Steubl, Baumeister) Department of Clinical Psychology and Psychotherapy, Institute of Psychology and Education, Ulm University, GermanyM. Domhardt, Department of Clinical Psychology and Psychotherapy, Ulm University, Lise-Meitner-Str. 16, Ulm 89081, Germany. E-mail: matthias.domhardt@uni-ulm.de
AN  - 2011248941
AU  - Domhardt,
AU  - M.
AU  - Schroder,
AU  - A.
AU  - Geirhos,
AU  - A.
AU  - Steubl,
AU  - L.
AU  - Baumeister,
AU  - H.
DA  - April
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.invent.2021.100373
DP  - Ovid Technologies
KW  - Adolescent mental health
KW  - eHealth
KW  - Internet- and mobile-based intervention
KW  - mHealth
KW  - Pediatrics
KW  - Psychotherapy
KW  - adolescent
KW  - anxiety
KW  - child
KW  - chronic disease
KW  - comparative effectiveness
KW  - controlled study
KW  - data extraction
KW  - depression
KW  - effect size
KW  - Embase
KW  - female
KW  - human
KW  - Internet
KW  - juvenile
KW  - male
KW  - Medline
KW  - mental disease
KW  - meta analysis
KW  - physiological stress
KW  - PsycINFO
KW  - quality of life
KW  - randomized controlled trial (topic)
KW  - review
KW  - risk assessment
KW  - self concept
KW  - systematic review
KW  - telehealth
L1  - internal-pdf://3392082346/Domhardt-2021.pdf
LA  - English
M3  - Review
PY  - 2021
T2  - Internet Interventions
TI  - Efficacy of digital health interventions in youth with chronic medical conditions: A meta-analysis
UR  - http://www.journals.elsevier.com/internet-interventions/
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2011248941
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.invent.2021.100373&amp;issn=2214-7829&amp;isbn=&amp;volume=24&amp;issue=&amp;spage=100373&amp;pages=&amp;date=2021&amp;title=Internet+Interventions&amp;atitle=Efficacy+of+digital+health+interventions+in+youth+with+chronic+medical+conditions%3A+A+meta-analysis&amp;aulast=Domhardt&amp;pid=%3Cauthor%3EDomhardt+M.%3C%2Fauthor%3E%3CAN%3E2011248941%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 24 (no pagination)
ER  -
TY  - JOUR
AB  - Organized sport is a context in which to promote positive youth development (PYD). Interventions with a PYD lens are often implemented to promote a wide range of physical or psychosocial benefits through sport participation. To date, no meta-analytic review of the effect of these interventions has been conducted. This is important because such interventions are held in high regard when it comes to policy development. In the present study, we conducted seven meta-analyses to evaluate the overall effect of sport-based interventions on PYD outcomes. Aspects of the study design and sample also were tested as moderators. In total, 35 studies (from 29 published articles) reporting on 74 effect sizes highlighted small to medium effects of PYD interventions on competence, confidence, and life skills outcomes. No significant overall effects were found for outcomes related to character, connection, PYD climate, and health. Further, moderation analyses showed that: (a) character was moderated by study design, sport type, and study duration; (b) competence was moderated by design and participant sex; and, (c) life skills were moderated by design, sport type, duration, and participant age. Implications for theory and practice concerning the use of sport-based interventions to influence PYD are discussed.
AN  - WOS:000614156200001
AU  - Bruner,
AU  - M.
AU  - W.
AU  - McLaren,
AU  - C.
AU  - D.
AU  - Sutcliffe,
AU  - J.
AU  - T.
AU  - Gardner,
AU  - L.
AU  - A.
AU  - Lubans,
AU  - D.
AU  - R.
AU  - Smith,
AU  - J.
AU  - J.
AU  - Vella,
AU  - S.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/1750984X.2021.1875496
L1  - internal-pdf://2385912834/Bruner.pdf
PY  - 2021
T2  - INTERNATIONAL REVIEW OF SPORT AND EXERCISE PSYCHOLOGY
TI  - The effect of sport-based interventions on positive youth development: a systematic review and meta-analysis
UR  - https://www.tandfonline.com/doi/full/10.1080/1750984X.2021.1875496
UR  - https://www.tandfonline.com/doi/pdf/10.1080/1750984X.2021.1875496?needAccess=true
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Innovations in virtual reality (VR) technologies have improved the adaptability of its use in therapeutic settings, and VR has shown to be a promising treatment for fear of medical procedures, with research increasing in this area in recent years. 

**PURPOSE**
This review aims to collate evidence for the impact of VR on fear of medical procedures. 

**METHODS**
CENTRAL (Cochrane), MEDLINE, EMBASE, and PsychINFO databases were searched up to October 2020. A mix of experimental and case-control studies were included for review, which evaluated the effectiveness of VR for fear, anxiety, and pain of medical procedures for people with needle phobia, dental phobia, claustrophobia of medical scans, and burn wound care anxiety. Risk of bias (RoB) was assessed by Cochrane and ROBINS-I tools. 

**RESULTS**
Twenty-eight studies were selected. Some studies included mixed participant groups of young people adults. The interventions varied, with VR used for distraction, hypnosis, or exposure. These were shown to be effective for reducing fear of medical procedures. However, effectiveness for blood-injection-injury phobias and burn wound care patients was unclear. 

**CONCLUSIONS**
Evidence on the effectiveness of VR suggests that it does decrease fear of medical procedures in some situations. However, the RoB assessment illustrated a poor quality of studies across those included in this review, limiting the ability to draw firm general conclusions from the study findings. There is a need for further research exploring the use of VR technologies in the management of anxiety in physical health care settings.
AN  - 33821879
AU  - Kilic,
AU  - A.
AU  - Brown,
AU  - A.
AU  - Aras,
AU  - I.
AU  - Hui,
AU  - R.
AU  - Hare,
AU  - J.
AU  - Hughes,
AU  - L.
AU  - D.
AU  - McCracken,
AU  - L.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/abm/kaab016
L1  - internal-pdf://1534928428/Kilic-2021-Using Virtual Technology for Fear o.pdf
PY  - 2021
SP  - 1062-1079
T2  - Annals of Behavioral Medicine
TI  - Using Virtual Technology for Fear of Medical Procedures: A Systematic Review of the Effectiveness of Virtual Reality-Based Interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=33821879
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8557375/pdf/kaab016.pdf
VL  - 55
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Anxiety, obsessive-compulsive, and stress-related disorders frequently co-occur, and patients often present symptoms of several domains. Treatment involves the use of selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), but data on comparative efficacy and acceptability are lacking. We aimed to compare the efficacy of SSRIs, SNRIs, and placebo in multiple symptom domains in patients with these diagnoses over the lifespan through a 3-level network meta-analysis. 

**METHODS AND FINDINGS**: We searched for published and unpublished randomized controlled trials that aimed to assess the efficacy of SSRIs or SNRIs in participants (adults and children) with diagnosis of any anxiety, obsessive-compulsive, or stress-related disorder in MEDLINE, PsycINFO, Embase, and Cochrane Library from inception to 23 April 2015, with an update on 11 November 2020. We supplemented electronic database searches with manual searches for published and unpublished randomized controlled trials registered in publicly accessible clinical trial registries and pharmaceutical companies&#039; databases. No restriction was made regarding comorbidities with any other mental disorder, participants&#039; age and sex, blinding of participants and researchers, date of publication, or study language. The primary outcome was the aggregate measure of internalizing symptoms of these disorders. Secondary outcomes included specific symptom domains and treatment discontinuation rate. We estimated standardized mean differences (SMDs) with 3-level network meta-analysis with random slopes by study for medication and assessment instrument. Risk of bias appraisal was performed using the Cochrane Collaboration&#039;s risk of bias tool. This study was registered in PROSPERO (CRD42017069090). We analyzed 469 outcome measures from 135 studies (n = 30,245). All medications were more effective than placebo for the aggregate measure of internalizing symptoms (SMD -0.56, 95% CI -0.62 to -0.51, p &lt; 0.001), for all symptom domains, and in patients from all diagnostic categories. We also found significant results when restricting to the most used assessment instrument for each diagnosis; nevertheless, this restriction led to exclusion of 72.71% of outcome measures. Pairwise comparisons revealed only small differences between medications in efficacy and acceptability. Limitations include the moderate heterogeneity found in most outcomes and the moderate risk of bias identified in most of the trials. 

**CONCLUSIONS**: In this study, we observed that all SSRIs and SNRIs were effective for multiple symptom domains, and in patients from all included diagnostic categories. We found minimal differences between medications concerning efficacy and acceptability. This three-level network meta-analysis contributes to an ongoing discussion about the true benefit of antidepressants with robust evidence, considering the significantly larger quantity of data and higher statistical power when compared to previous studies. The 3-level approach allowed us to properly assess the efficacy of these medications on internalizing psychopathology, avoiding potential biases related to the exclusion of information due to distinct assessment instruments, and to explore the multilevel structure of transdiagnostic efficacy.
AN  - 34111122
AU  - Gosmann,
AU  - N.
AU  - P.
AU  - Costa,
AU  - M.
AU  - A.
AU  - Jaeger,
AU  - M.
AU  - B.
AU  - Motta,
AU  - L.
AU  - S.
AU  - Frozi,
AU  - J.
AU  - Spanemberg,
AU  - L.
AU  - Manfro,
AU  - G.
AU  - G.
AU  - Cuijpers,
AU  - P.
AU  - Pine,
AU  - D.
AU  - S.
AU  - Salum,
AU  - G.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pmed.1003664
L1  - internal-pdf://1369087407/Gosmann-2021-Selective serotonin reuptake inhi.pdf
PY  - 2021
SP  - e1003664
T2  - PLoS Medicine / Public Library of Science
TI  - Selective serotonin reuptake inhibitors, and serotonin and norepinephrine reuptake inhibitors for anxiety, obsessive-compulsive, and stress disorders: A 3-level network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34111122
UR  - https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pmed.1003664/2/pmed.1003664.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&amp;X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210825%2Fauto%2Fstorage%2Fgoog4_request&amp;X-Goog-Date=20210825T075751Z&amp;X-Goog-Expires=86400&amp;X-Goog-SignedHeaders=host&amp;X-Goog-Signature=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
VL  - 18
ER  -
TY  - JOUR
AB  - **Background**
Autistic spectrum disorder (ASD) is an increasingly recognised neurodevelopmental condition; that is, a neurologically‐based condition which interferes with the acquisition, retention or application of specific skills. ASD is characterised by challenges with socialisation and communication, and by stereotyped and repetitive behaviours. A stereotyped behaviour is one which is repeated over and over again and which seems not to have any useful function. ASD often co‐occurs with mental health disorders, including obsessive compulsive disorder (OCD). People with ASD may show certain cognitive differences (i.e. differences in ways of thinking) which influence their response to therapies. Thus, there is a need for evidence‐based guidelines to treat mental health issues in this group.

OCD, a common condition characterised by repeated obsessional thoughts and compulsive acts, occurs with greater frequency in persons with ASD than in the general population. Genetic, anatomic, neurobiological and psychological factors have been proposed to explain this co‐occurrence. However, care should be taken to distinguish stereotyped and repetitive behaviours characteristic of ASD from obsessive compulsive acts in OCD.

Cognitive behavioural therapy (CBT) is the recommended treatment for OCD, but studies have suggested that this treatment may be less effective in those with OCD co‐occurring with ASD. Hence, modifications to CBT treatment may be helpful when treating OCD co‐occurring with ASD to optimise outcomes.

**Objectives**
To assess the effectiveness of behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in children and adults with autism spectrum disorder (ASD).

**Search methods**
We searched for studies in the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, PsycINFO, five other bibliographic databases, international trial registries and other sources of grey literature (to 24 August 2020). We checked the reference lists of included studies and relevant systematic reviews to identify additional studies missed from the original electronic searches. We contacted subject experts for further information when needed.

**Selection criteria**
We included randomised controlled trials (RCTs), cross‐over, cluster‐ and quasi‐randomised controlled trials involving both adults and children with diagnoses of OCD and ASD. We included studies of participants with co‐occurring conditions (i.e. those experiencing other mental illnesses or neurodevelopmental conditions at the same time), but we did not include individuals who had a co‐occurring global learning difficulty. Treatment could be in any setting or format and include behavioural therapy (BT) and cognitive behavioural therapy (CBT), which may have been adapted for those with ASD. Comparator interventions included no treatment, waiting list, attention placebo (where the control group receives non‐specific aspects of therapy, but not the active ingredient) and treatment as usual (TAU, where the control group receives the usual treatment, according to accepted standards).

**Data collection and analysis**
Three review authors independently screened studies for inclusion. The authors extracted relevant data from the one eligible study, assessed the risk of bias and certainty of evidence (GRADE). Outcomes of interest were changes in OCD symptoms and treatment completion (primary outcome), and severity of depressive symptoms, anxiety symptoms and behavioural difficulties, as well as degree of family accommodation (secondary outcomes). We did not conduct meta‐analyses as only one study met the selection criteria.

**Main results**
We included only one RCT of 46 participants in our analysis. This study compared CBT for OCD in persons with high‐functioning ASD with a control group who received anxiety management only. There were no differences in rates of treatment completion between the CBT (87%) and anxiety management (87%) groups (risk ratio (RR) 1.00, 95% confidence interval (CI) 0.80 to 1.25; low‐certainty evidence). Behavioural difficulties were not included as an outcome measure in the study. This study showed that there may be a benefit at the end of treatment favouring CBT compared with anxiety management in OCD symptoms (mean difference (MD) ‐3.00, 95% CI ‐8.02 to 2.02), depression symptoms (MD ‐1.80, 95% CI ‐11.50 to 7.90), anxiety symptoms (MD ‐3.20, 95% CI ‐11.38 to 4.98), and quality of life (MD 5.20, 95% CI ‐1.41 to 11.81), but the evidence was of low certainty. 

**Authors&#039; conclusions**
Evidence is limited regarding the efficacy of CBT for treatment of OCD in ASD. There is much scope for future study, not only examining the efficacy of CBT for OCD in ASD, but also the particular ways that OCD manifests in and affects people with ASD and the role of the family in treatment response.
AN  - CD013173
AU  - Elliott,
AU  - S.
AU  - J.
AU  - Marshall,
AU  - D.
AU  - Morley,
AU  - K.
AU  - Uphoff,
AU  - E.
AU  - Kumar,
AU  - M.
AU  - Meader,
AU  - N.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1002/14651858.CD013173.pub2
N1  - [Common Mental Disorders, Developmental, Psychosocial and Learning Problems]
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD)
UR  - http://dx.doi.org/10.1002/14651858.CD013173.pub2
ER  -
TY  - JOUR
AB  - **BACKGROUND**: There is a risk of adverse neurodevelopmental outcomes in offspring from exposure to antidepressants during pregnancy.OBJECTIVE: This study was performed to systematically review the available evidence regarding the impact of in utero exposure to antidepressants on motor and intellectual disability outcomes in children.

**PATIENTS AND METHODS**: A systematic literature search for published observational studies examining the effects of antidepressants on motor development or intellectual disabilities in children was conducted using the Cochrane Central Register of Controlled Trials, PubMed/Medline, and Google Scholar.

**RESULTS**: A total of 14 studies were included in this review. Studies have reported conflicting effects on motor development in infants with maternal exposure to antidepressants. Furthermore, not all of the studies included that assessed intellectual disabilities in infants found an association between maternal exposure to antidepressants and intellectual disabilities. However, methodological flaws existed in the studies, such as the use of scales with inadequate reliability or validity, a lack of statistical power, or confounding by indication or disease severity.

**CONCLUSION**: The available literature provides inconclusive evidence on the relationship between in utero exposure to antidepressants and adverse effects on motor development outcomes or neurocognitive skills. Further observational studies with robust methodologies are needed to comprehensively evaluate the potential risks of prescribing antidepressants during pregnancy.
AD  - Al-Fadel, Nouf. Saudi Food and Drug Authority, Riyadh, Saudi Arabia. nsfadel@sfda.gov.sa.Alrwisan, Adel. Saudi Food and Drug Authority, Riyadh, Saudi Arabia.
AN  - 33576941
AU  - Al-Fadel,
AU  - N.
AU  - Alrwisan,
AU  - A.
DA  - Jun
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40801-021-00232-z
DP  - Ovid Technologies
J2  - Drugs - real world outcomes
L1  - internal-pdf://3662419433/Al-Fadel-2021.pdf
LA  - English
M3  - Systematic Review
N1  - Al-Fadel, NoufAlrwisan, Adel
PY  - 2021
SP  - 105-123
T2  - Drugs Real World Outcomes
TI  - Antidepressant Use During Pregnancy and the Potential Risks of Motor Outcomes and Intellectual Disabilities in Offspring: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=33576941
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128961/pdf/40801_2021_Article_232.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To conduct a systematic review and meta-analysis to compare the efficacy and safety of umbilical cord milking (UCM) versus delayed cord clamping (DCC) in term and late-preterm infants. 

**METHODS: **
MEDLINE, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials, Clinical trial registries, and Gray literature were searched for randomized controlled trials (RCTs) comparing UCM with DCC in term and late-preterm infants for both short-term and long-term outcomes. Intact and cut UCM were compared separately with DCC using subgroup analysis. We used fixed effect model to pool the data. Random effects model was used when there was significant heterogeneity. 

**RESULTS: **
Nine studies (1632 infants) were included in the systematic review. Milking was performed on intact cord (i-UCM) in five studies (n = 829) and on cut cord (c-UCM) in four studies (n = 803). Cord milking significantly improved hemoglobin level at 48-72 h of life when compared to DCC (six studies, n = 924, mean difference 0.36 g/dL; 95% CI: 0.19-0.53). In addition, hemoglobin level at six to eight weeks of age was also significantly higher in the studies comparing i-UCM with DCC (two studies, n = 550: mean difference 0.16 g/dL; 95% CI: 0.06-0.27). There was no difference between the UCM group and DCC group for any other outcome. Only one study provided information on growth and hematological parameters at one year of age. Neurodevelopmental outcomes were not reported. None of the studies included non-vigorous infants. The grade of evidence was low to very low for all the outcomes studied. 

**CONCLUSION: **
UCM is comparable to DCC in improving short-term hematological outcomes in term and late-preterm vigorous infants. Trials assessing the effect of UCM on important clinical and long-term outcomes among non-vigorous mature preterm infants are urgently required.
AN  - 33567910
AU  - Jeevan,
AU  - A.
AU  - Ananthan,
AU  - A.
AU  - Bhuwan,
AU  - M.
AU  - Balasubramanian,
AU  - H.
AU  - Rao,
AU  - S.
AU  - Kabra,
AU  - N.
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/14767058.2021.1884676
L1  - internal-pdf://0264774556/Jeevan-2021-Umbilical cord milking versus dela.pdf
PY  - 2021
SP  - 1-11
T2  - Journal of Maternal-Fetal &amp; Neonatal Medicine
TI  - Umbilical cord milking versus delayed cord clamping in term and late-preterm infants: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33567910
UR  - https://www.tandfonline.com/doi/full/10.1080/14767058.2021.1884676
UR  - https://www.tandfonline.com/doi/pdf/10.1080/14767058.2021.1884676?needAccess=true
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Research about skin-to-skin care (SSC) experiences in early period after birth has focused on mothers and infants. 

**PURPOSE**: The purpose of this study was to determine the outcomes of paternal skin-to-skin care (P-SSC) in both fathers and infants. 

**METHODS**: The Cochrane Central Register of Controlled Trials (CENTRAL), PubMed/MEDLINE, Embase, CINAHL, PsycInfo, Airiti Library, and Google Scholar were searched for randomized controlled trials (RCTs) that reported outcomes of P-SSC in both fathers and infants. We calculated pooled mean differences (MDs) and 95% confidence intervals (CIs) using RevMan 5.3 for the meta-analysis [PROSPERO: CRD42018106790]. 

**RESULTS**: Seven RCTs including a total of 552 participants were eligible for inclusion. Compared to the maternal skin-to-skin care (M-SSC), fathers in the P-SSC exhibited no significant differences in salivary oxytocin levels (MD: -0.35 pg/mL; 95% CI: -0.75, 0.05), salivary cortisol levels (MD: 0.25 mug/dL; 95% CI: -0.82, 1.33), or anxiety scores (MD: -0.17; 95% CI: -0.57, 0.22) during the period of SSC. Similarly, there were no significant differences in the salivary cortisol levels (MD: -0.11 mug/dL; 95% CI: -0.05, 0.28) among preterm infants between the 2 groups. However, the crying time was less among full-term infants in the P-SSC group compared with infants in the incubator care or cot care groups. 

**IMPLICATIONS FOR PRACTICE AND RESEARCH**: P-SSC had similar effects as M-SSC on stress-related outcomes during and after SSC among fathers and infants in the early stages after birth. We recommend that P-SSC be implemented in the early stages after birth. Further RCTs with a longitudinal design and large samples are needed to better understand the long-term effects of P-SSC on fathers and infants.
AN  - 34054012
AU  - Kuo,
AU  - S.
AU  - F.
AU  - Chen,
AU  - I.
AU  - H.
AU  - Chen,
AU  - S.
AU  - R.
AU  - Chen,
AU  - K.
AU  - H.
AU  - Fernandez,
AU  - R.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/ANC.0000000000000890
L1  - internal-pdf://0193704700/Kuo-2021-The Effect of Paternal Skin-to-Skin C.pdf
PY  - 2021
SP  - 27
T2  - Advances in Neonatal Care
TI  - The Effect of Paternal Skin-to-Skin Care: A Systematic Review and Meta-analysis of Randomized Control Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34054012
VL  - 27
ER  -
TY  - JOUR
AB  - **Background**: The impact of maternal obesity extends beyond birth, being independently associated with an increased risk of child obesity. Current evidence demonstrates that women provided with a dietary intervention during pregnancy improve their dietary quality and have a modest reduction in gestational weight gain. However, the effect of this on longer-term childhood obesity-related outcomes is unknown. 

**Method(s)**: We conducted an individual participant data meta-analysis from RCTs in which women with a singleton, live gestation between 10&lt;sup&gt;+0&lt;/sup&gt; and 20&lt;sup&gt;+0&lt;/sup&gt; weeks and body mass index (BMI) &gt;= 25 kg/m&lt;sup&gt;2&lt;/sup&gt; in early pregnancy were randomised to a diet and/or lifestyle intervention or continued standard antenatal care and in which longer-term maternal and child follow-up at 3-5 years of age had been undertaken. The primary childhood outcome was BMI z-score above the 90th percentile. Secondary childhood outcomes included skinfold thickness measurements and body circumferences, fat-free mass, dietary and physical activity patterns, blood pressure, and neurodevelopment. 

**Result(s)**: Seven primary trials where follow-up of participants occurred were identified by a systematic literature search within the International Weight Management in Pregnancy (i-WIP) Collaborative Group collaboration, with six providing individual participant data. No additional studies were identified after a systematic literature search. A total of 2529 children and 2383 women contributed data. Approximately 30% of all child participants had a BMI z-score above the 90th percentile, with no significant difference between the intervention and control groups (aRR 0.97; 95% CI 0.87, 1.08; p=0.610). There were no statistically significant differences identified for any of the secondary outcome measures. 

**Conclusion(s)**: In overweight and obese pregnant women, we found no evidence that maternal dietary and/or lifestyle intervention during pregnancy modifies the risk of early childhood obesity. Future research may need to target the pre-conception period in women and early childhood interventions. Trial registration: PROSPERO, CRD42016047165 Copyright &copy; 2021, The Author(s).
AN  - 2012306963
AU  - Louise,
AU  - J.
AU  - Poprzeczny,
AU  - A.
AU  - J.
AU  - Deussen,
AU  - A.
AU  - R.
AU  - Vinter,
AU  - C.
AU  - Tanvig,
AU  - M.
AU  - Jensen,
AU  - D.
AU  - M.
AU  - Bogaerts,
AU  - A.
AU  - Devlieger,
AU  - R.
AU  - McAuliffe,
AU  - F.
AU  - M.
AU  - Renault,
AU  - K.
AU  - M.
AU  - Carlsen,
AU  - E.
AU  - Geiker,
AU  - N.
AU  - Poston,
AU  - L.
AU  - Briley,
AU  - A.
AU  - Thangaratinam,
AU  - S.
AU  - Dodd,
AU  - J.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12916-021-01995-6
L1  - internal-pdf://0570013975/Louise-2021-The effects of dietary and lifesty.pdf
PY  - 2021
T2  - BMC Medicine
TI  - The effects of dietary and lifestyle interventions among pregnant women with overweight or obesity on early childhood outcomes: an individual participant data meta-analysis from randomised trials
UR  - http://www.biomedcentral.com/bmcmed/
UR  - https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-021-01995-6.pdf
VL  - 19 (1) (no pagination)
ER  -
TY  - JOUR
AB  - Individuals with Autism Spectrum Disorder may engage in repetitive vocal behaviors which interfere with a structured environment and social inclusion. If untreated, these vocal behaviors maintain into adulthood potentially impeding gainful employment and independent living. 

This analysis specifically focused on treatments available for presumed or functionally determined automatically reinforced repetitive vocal behaviors, also known as vocal stereotypy. For this review, a systematic keyword search of the literature identified 66 articles and a Tau-U measure of effect size was calculated for 34 eligible studies in order to determine impact of interventions on vocal stereotypy. Of the single-component interventions assessed, three interventions demonstrated a very large effect: interactive activity (0.94), self-management (0.89), and response interruption and redirection (interrupted measurement, 0.86). Additionally, 92% of treatment packages reached a very large effect (0.85-1.00), all of which included stimulus control and/or response cost intervention components. 

Theoretical and practical applications are discussed, as well as implications for future research.
AN  - WOS:000740539300001
AU  - Mantzoros,
AU  - T.
AU  - McCoy,
AU  - A.
AU  - R.
AU  - Lee,
AU  - D.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/bin.1856
L1  - internal-pdf://2553716833/Treatments for automatically reinforced vocal.pdf
PY  - 2021
SP  - 20
T2  - Behavioral Interventions
TI  - Treatments for automatically reinforced vocal stereotypy for individuals with autism spectrum disorder: A literature and meta-analytic review
UR  - &lt;Go to ISI&gt;://WOS:000740539300001
UR  - https://onlinelibrary.wiley.com/doi/10.1002/bin.1856
ER  -
TY  - JOUR
AB  - Animal-assisted intervention (AAI) has garnered public interest and has been implemented for youth with autism spectrum disorders-a practice supported by anecdotal evidence. While investigations of AAI for children with autism have been conducted, the extant literature is characterized by significant variability in methodology and practice. The present meta-analysis examines the aggregated effects of equine AAI on adaptive functioning among children with autism. Results indicated that interacting with an equine specifically during AAI produced small-to-medium effects (g = 0.40) on the adaptive functioning of children with autism. Recommendations are made for future research on this topic. Copyright &copy; 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.
AD  - (Droboniku, Mychailyszyn) Department of Psychology, Towson University, Towson, MD 21252, United States (Droboniku) Department of Psychology, University of Cincinnati, Cincinnati, OH 45220, United States (Mychailyszyn) Division of Pediatric Psychology &amp; Neuropsychology, Mt. Washington Pediatric Hospital, Baltimore, MD 21209, United StatesM.J. Droboniku, Department of Psychology, Towson University, Towson, MD 21252, United States. E-mail: Droboniku8@gmail.com
AN  - 2010485379
AU  - Droboniku,
AU  - M.
AU  - J.
AU  - Mychailyszyn,
AU  - M.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-021-04891-3
DP  - Ovid Technologies
KW  - Animal-assisted intervention
KW  - Autism spectrum disorder
KW  - Meta-analysis
KW  - Youth
KW  - article
KW  - autism
KW  - child
KW  - Equus
KW  - female
KW  - human
KW  - juvenile
KW  - male
KW  - meta analysis
KW  - nonhuman
L1  - internal-pdf://2564332862/Droboniku-2021-Animal Interaction Affecting Co.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2021
PY  - 2021
T2  - Journal of Autism and Developmental Disorders.
TI  - Animal Interaction Affecting Core Deficit Domains Among Children with Autism: A Meta-Analysis
UR  - http://www.wkap.nl/journalhome.htm/0162-3257
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010485379
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33582878&amp;id=doi:10.1007%2Fs10803-021-04891-3&amp;issn=0162-3257&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+Autism+and+Developmental+Disorders&amp;atitle=Animal+Interaction+Affecting+Core+Deficit+Domains+Among+Children+with+Autism%3A+A+Meta-Analysis&amp;aulast=Droboniku&amp;pid=%3Cauthor%3EDroboniku+M.J.%3C%2Fauthor%3E%3CAN%3E2010485379%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s10803-021-04891-3.pdf
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Cognitive behavioural therapy (CBT), incorporating exposure and response prevention (ERP) is widely recognised as the psychological treatment of choice for obsessive-compulsive disorder (OCD). Uncertainty remains however about the magnitude of the effect of CBT with ERP and the impact of moderating factors in patients with OCD.

**METHOD**: This systematic review and meta-analysis assessed randomised-controlled trials of CBT with ERP in patients of all ages with OCD. The study was preregistered in PROSPERO (CRD42019122311). The primary outcome was end-of-trial OCD symptom scores. The moderating effects of patient-related and study-related factors including type of control intervention and risk of bias were examined. Additional exploratory analyses assessed the effects of treatment fidelity and impact of researcher allegiance.

**RESULTS**: Thirty-six studies were included, involving 2020 patients (537 children/adolescents and 1483 adults) with 1005 assigned to CBT with ERP and 1015 to control conditions. When compared against all control conditions, a large pooled effect size (ES) emerged in favour of CBT with ERP (g = 0.74: 95% CI = 0.51 to 0.97 k = 36), which appeared to diminish with increasing age. While CBT with ERP was more effective than psychological placebo (g = 1.13 95% CI 0.71 to 1.55, k = 10), it was no more effective than other active forms of psychological therapy (g = -0.05: 95% CI -0.27 to 0.16, k = 8). Similarly, whereas CBT with ERP was significantly superior when compared to all forms of pharmacological treatment (g = 0.36: 95% CI 0.7 to 0.64, k = 7), the effect became marginal when compared with adequate dosages of pharmacotherapy for OCD (g = 0.32: 95% CI -0.00 to 0.64, k = 6). A minority of studies (k = 8) were deemed to be at low risk of bias. Moreover, three quarters of studies (k = 28) demonstrated suspected researcher allegiance and these studies reported a large ES (g = 0.95: 95% CI 0.69 to 1.2), while those without suspected researcher allegiance (k = 8) indicated that CBT with ERP was not efficacious (g = 0.02: 95% CI -0.29 to 0.33).

**CONCLUSIONS**: A large effect size was found for CBT with ERP in reducing the symptoms of OCD, but depends upon the choice of comparator control. This meta-analysis also highlights concerns about the methodological rigor and reporting of published studies of CBT with ERP in OCD. In particular, efficacy was strongly linked to researcher allegiance and this requires further future investigation.
AD  - Reid, Jemma E. University of Hertfordshire, Hatfield, Hertfordshire, UK; Hertfordshire Partnership University NHS Foundation Trust, Hertfordshire, UK. Electronic address: jemma.reid1@nhs.net.Laws, Keith R. University of Hertfordshire, Hatfield, Hertfordshire, UK.Drummond, Lynne. South West London and St George&#039;s NHS Trust, UK.Vismara, Matteo. University of Milan, Department of Biomedical and Clinical Sciences Luigi Sacco, Milano, Italy.Grancini, Benedetta. University of Milan, Department of Biomedical and Clinical Sciences Luigi Sacco, Milano, Italy.Mpavaenda, Davis. University of Hertfordshire, Hatfield, Hertfordshire, UK; Hertfordshire Partnership University NHS Foundation Trust, Hertfordshire, UK.Fineberg, Naomi A. University of Hertfordshire, Hatfield, Hertfordshire, UK; Hertfordshire Partnership University NHS Foundation Trust, Hertfordshire, UK; University of Cambridge School of Clinical Medicine, Cambridge, UK.
AN  - 33618297
AU  - Reid,
AU  - J.
AU  - E.
AU  - Laws,
AU  - K.
AU  - R.
AU  - Drummond,
AU  - L.
AU  - Vismara,
AU  - M.
AU  - Grancini,
AU  - B.
AU  - Mpavaenda,
AU  - D.
AU  - Fineberg,
AU  - N.
AU  - A.
DA  - Feb 02
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.comppsych.2021.152223
DP  - Ovid Technologies
J2  - Compr Psychiatry
L1  - internal-pdf://0114565247/Reid-2021.pdf
LA  - English
M3  - Review
N1  - Reid, Jemma ELaws, Keith RDrummond, LynneVismara, MatteoGrancini, BenedettaMpavaenda, DavisFineberg, Naomi AS0010-440X(21)00001-8
PY  - 2021
SP  - 152223
T2  - Comprehensive Psychiatry
TI  - Cognitive behavioural therapy with exposure and response prevention in the treatment of obsessive-compulsive disorder: A systematic review and meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33618297
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33618297&amp;id=doi:10.1016%2Fj.comppsych.2021.152223&amp;issn=0010-440X&amp;isbn=&amp;volume=106&amp;issue=&amp;spage=152223&amp;pages=152223&amp;date=2021&amp;title=Comprehensive+Psychiatry&amp;atitle=Cognitive+behavioural+therapy+with+exposure+and+response+prevention+in+the+treatment+of+obsessive-compulsive+disorder%3A+A+systematic+review+and+meta-analysis+of+randomised+controlled+trials.&amp;aulast=Reid&amp;pid=%3Cauthor%3EReid+JE%3C%2Fauthor%3E%3CAN%3E33618297%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 106
ER  -
TY  - JOUR
AB  - Despite accumulating evidence suggesting the effectiveness of Attention Bias Modification (ABM) in adults, little is known about its efficacy in children and adolescents. As anxiety has been the chief target in most studies and research in this area has grown rapidly in recent years, we conducted the first meta-analysis to establish the effects of ABM alone for anxiety disorders in children and adolescents. 

Studies were identified through a systematic search in three main databases: PubMed, EMBASE and PsycInfo, resulting in 17 randomized studies. The quality of these studies, possible publication bias and moderators were then examined. ABM had small but significant effects on clinician-rated anxiety symptoms and attention bias towards threat, while the effect on self or parent-reported anxiety measures was non-significant. Evidence quality ranged from moderate to very low. ABM was more effective when conducted as a stand-alone treatment than as an adjunct to other treatments. In addition, younger age and larger number of training sessions were associated with a greater reduction in clinician-rated anxiety symptoms. 

Results indicate that ABM may have significant effects on anxiety and attention bias in children and adolescents. Overall, the effects of ABM are mainly evident when clinical outcome is assessed by a clinician. Copyright &copy; 2021
AD  - (Hang, Zhang, Wang, Zhang, Liu) Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing 210029, China (Hang, Zhang, Wang) School of Psychology, Nanjing Normal University, Nanjing 210097, China (Wang, Zhang) Cognitive Behavioral Therapy Institute of Nanjing Medical University, Nanjing 210029, China (Wang, Zhang) Functional Brain Imaging Institute of Nanjing Medical University, Nanjing 210029, ChinaC. Wang, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing 210029, China. E-mail: fm51109@163.com
AN  - 2011531650
AU  - Hang,
AU  - Y.
AU  - Zhang,
AU  - G.
AU  - Wang,
AU  - C.
AU  - Zhang,
AU  - N.
AU  - Liu,
AU  - G.
DA  - June
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.psychres.2021.113896
DP  - Ovid Technologies
KW  - Adolescents
KW  - Anxiety disorder
KW  - Attention bias modification
KW  - Children
KW  - Meta-analysis
KW  - Review
KW  - adolescent
KW  - attentional bias
KW  - child
KW  - clinical assessment
KW  - clinical outcome
KW  - Embase
KW  - female
KW  - human
KW  - male
KW  - Medline
KW  - meta analysis
KW  - outcome assessment
KW  - PsycINFO
KW  - publication bias
KW  - randomized controlled trial (topic)
KW  - systematic review
L1  - internal-pdf://1407856531/Hang-2021.pdf
LA  - English
M3  - Review
PY  - 2021
T2  - Psychiatry Research
TI  - Attention bias modification for anxiety disorders in children and adolescents: A systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/psychres
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2011531650
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33799199&amp;id=doi:10.1016%2Fj.psychres.2021.113896&amp;issn=0165-1781&amp;isbn=&amp;volume=300&amp;issue=&amp;spage=113896&amp;pages=&amp;date=2021&amp;title=Psychiatry+Research&amp;atitle=Attention+bias+modification+for+anxiety+disorders+in+children+and+adolescents%3A+A+systematic+review+and+meta-analysis&amp;aulast=Hang&amp;pid=%3Cauthor%3EHang+Y.%3C%2Fauthor%3E%3CAN%3E2011531650%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 300 (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Available evidence on the comparative efficacy and acceptability of psychotherapies for post-traumatic stress disorder (PTSD) in children and adolescents remains uncertain. 

**OBJECTIVE**
We aimed to compare and rank the different types and formats of psychotherapies for PTSD in children and adolescents. 

**METHODS**
We searched eight databases and other international registers up to 31 December 2020. The pairwise meta-analyses and frequentist network meta-analyses estimated pooled standardised mean differences (SMDs) and ORs with random-effects model. Efficacy at post-treatment and follow-up, acceptability, depressive and anxiety symptoms were measured. 

**FINDINGS**
 We included 56 randomised controlled trials with 5327 patients comparing 14 different types of psychotherapies and 3 control conditions. For efficacy, cognitive processing therapy (CPT), behavioural therapy (BT), individual trauma-focused cognitive-behavioural therapy (TF-CBT), eye movement desensitisation and reprocessing, and group TF-CBT were significantly superior to all control conditions at post-treatment and follow-up (SMDs between -2.42 and -0.25). Moreover, CPT, BT and individual TF-CBT were more effective than supportive therapy (SMDs between -1.92 and -0.49). Results for depressive and anxiety symptoms were similar to the findings for the primary outcome. Most of the results were rated as &#039;moderate&#039; to &#039;very low&#039; in terms of confidence of evidence. 

**CONCLUSIONS**
CPT, BT and individual TF-CBT appear to be the best choices of psychotherapy for PTSD in young patients. Other types and different ways of delivering psychological treatment can be alternative options. Clinicians should consider the importance of each outcome and the patients&#039; preferences in real clinical practice.
AN  - 34599050
AU  - Xiang,
AU  - Y.
AU  - Cipriani,
AU  - A.
AU  - Teng,
AU  - T.
AU  - Del
AU  - Giovane,
AU  - C.
AU  - Zhang,
AU  - Y.
AU  - Weisz,
AU  - J.
AU  - R.
AU  - Li,
AU  - X.
AU  - Cuijpers,
AU  - P.
AU  - Liu,
AU  - X.
AU  - Barth,
AU  - J.
AU  - Jiang,
AU  - Y.
AU  - Cohen,
AU  - D.
AU  - Fan,
AU  - L.
AU  - Gillies,
AU  - D.
AU  - Du,
AU  - K.
AU  - Ravindran,
AU  - A.
AU  - V.
AU  - Zhou,
AU  - X.
AU  - Xie,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/ebmental-2021-300346
L1  - internal-pdf://1020318603/Xiang-2021-Comparative efficacy and acceptabil.pdf
PY  - 2021
SP  - 153-160
T2  - Evidence-Based Mental Health
TI  - Comparative efficacy and acceptability of psychotherapies for post-traumatic stress disorder in children and adolescents: a systematic review and network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34599050
UR  - https://www.zora.uzh.ch/id/eprint/207232/1/ebmental-2021-300346.full.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - This review analyses educational intervention studies that have researched the effects of physical activity in school on schoolchildren&#039;s cognition. Twenty-nine intervention studies carried out between January 2005 and the end of June 2019 were retrieved from five databases. Fourteen papers analysed the physically activity in academic lessons (PAAL) method, nine analysed the effects of active lesson breaks (ALB), two analysed active recess (AR) intervention, and three analysed combined physical activity (CPA) interventions consisting of two or more types of physical activity. Physical activity in school time has acute and chronic positive effects on cognition in children. In all the interventions (PAAL, ALB, AR, and CPA) short-term high-intensity physical activity sessions improved cognitive performance. Medium- to long-term moderate vigorous physical activity sessions also produced improvements in cognitive performance. The implications of including CPA programmes in the school timetable are discussed and practical guidelines with recommendations are offered.
AN  - WOS:000599749400005
AU  - Martinez-Lopez,
AU  - E.
AU  - J.
AU  - Ruiz-Ariza,
AU  - A.
AU  - De
AU  - La
AU  - Torre-Cruz,
AU  - M.
AU  - Suarez-Manzano,
AU  - S.
DA  - JAN
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.5093/psed2020a16
L1  - internal-pdf://2869762326/Martinez-Lopez-2021.pdf
PY  - 2021
SP  - 37-50
T2  - PSICOLOGIA EDUCATIVA
TI  - Alternatives of Physical Activity within School Times and Effects on Cognition. A Systematic Review and Educational Practical Guide
UR  - https://journals.copmadrid.org/psed/archivos/1135_755X_psed_27_1_0037.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - **Background**: Existing research indicates that spending time in nature is associated with diverse aspects of children&#039;s health and wellbeing. Although fundamental to later life chances and health, no systematic reviews, to our knowledge, have focused specifically on the effects of interaction with nature on socioemotional functioning in childhood. Objectives: Amongst children, what is the consistency of associations between the availability of or spending time in nature on socioemotional function and development? Furthermore, which child behaviours and states independently associate with socioemotional function and availability of or spending time in nature, and what is the consistency of associations between these behaviours and states and contact with nature? Data sources: Embase, Environment Complete, MEDLINE, and APA PsycINFO. Eligible studies were backward and forward snowball-searched. Study eligibility criteria: Studies investigating effects of, or associations between, availability of or interaction with nature on socioemotional or proximal outcomes in children under the age of 12 years were included in this review. Study appraisal and synthesis methods: The internal validity of studies investigating socioemotional outcomes were based on assessments of elements of study design, conduct, and reporting to identify potential issues related to confounding or other biases. The number of analyses indicating positive, negative, and non-significant associations between availability or interaction with green space and the outcomes were summed. 

**Results**: A total of 223 eligible full-texts, of which 43 pertained to socioemotional outcomes and 180 to proximal outcomes, met eligibility criteria. Positive associations between availability of and spending time in green space were found with children&#039;s intra- and interpersonal socioemotional function and development. Proportions of positive findings ranged from 13.9% to 55% across experimental and observational research, exposures, populations, and contexts. Modifying and mediating factors were identified. We found consistent evidence for improved aspects of cognition and, for children over six years, reduced risk of obesity and overweight in association with green space; consistent links between movement behaviours in the experimental, but not observational research; tentative trends suggesting associations with play, motor skills, language, screen time, and communication skills; little evidence for positive associations between green space and mood, physical wellbeing, and stress; some evidence for associations with healthy birth outcomes, and little evidence for direct associations between availability of green space and asthma and allergy prevalence, however, mediation via, for example, air pollution was likely. Limitations: We identified few studies without either probable or severe risk of bias in at least one item. Improved study quality may therefore result in different results. Restricting analyses to include only studies considered at low risk of bias indicated similar or slightly lower proportions of positive findings. Risk of bias in proximal outcomes was not assessed. 

**Conclusions**: The empirical evidence for benefits of availability of and interaction green space for child socioemotional function and development must currently be considered limited. A number of proximal indicators were identified.
AN  - WOS:000604626300009
AU  - Mygind,
AU  - L.
AU  - Kurtzhals,
AU  - M.
AU  - Nowell,
AU  - C.
AU  - Melby,
AU  - P.
AU  - S.
AU  - Stevenson,
AU  - M.
AU  - P.
AU  - Nieuwenhuijsen,
AU  - M.
AU  - Lum,
AU  - J.
AU  - A.
AU  - G.
AU  - Flensborg-Madsen,
AU  - T.
AU  - Bentsen,
AU  - P.
AU  - Enticott,
AU  - P.
AU  - G.
DA  - JAN
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.envint.2020.106238
L1  - internal-pdf://1653018668/Mygind-2021-Landscapes of becoming social_ A s.pdf
PY  - 2021
T2  - ENVIRONMENT INTERNATIONAL
TI  - Landscapes of becoming social: A systematic review of evidence for associations and pathways between interactions with nature and socioemotional development in children
VL  - 146
ER  -
TY  - JOUR
AB  - **Introduction** Mental health disorders and low levels of mental well-being can have a lasting effect on life satisfaction and contribution to society for children and adolescents, yet the effectiveness of occupational therapy interventions is unknown. 

**Methods** A mixed methods systematic review was conducted including studies with children and adolescents aged 5-16 years, who had mental health difficulties, that evaluated occupational therapy interventions and focused on participation in everyday occupations as an outcome. 

**Results** The nine included studies were generally very low quality. The results could not be pooled due to heterogeneity. For children with Asperger&#039;s syndrome, the Cognitive Orientation to Daily Occupational Performance intervention had clinically significant improvements on occupational performance and social skills. For children with attention deficit hyperactivity disorder, the Ultimate Guide to Play, Language and Friendship intervention improved playfulness and the Cognitive-Functional intervention had a statistically significant improvement on occupational performance and behaviour. 

**Conclusion** One intervention used by occupational therapists with children with Asperger&#039;s syndrome and two interventions used with children with attention deficit hyperactivity disorder had some evidence of effect. No evidence was identified for the effectiveness of occupational therapy interventions for children and adolescents with other common mental health conditions.
AN  - WOS:000677283700001
AU  - Brooks,
AU  - R.
AU  - Bannigan,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/03080226211008718
L1  - internal-pdf://3325518568/Brooks-2021-Occupational therapy interventions.pdf
PY  - 2021
SP  - 474-487
T2  - British Journal of Occupational Therapy
TI  - Occupational therapy interventions in child and adolescent mental health to increase participation: A mixed methods systematic review
UR  - &lt;Go to ISI&gt;://WOS:000677283700001
UR  - https://journals.sagepub.com/doi/pdf/10.1177/03080226211008718
VL  - 84
ER  -
TY  - JOUR
AB  - The human gut microbiome influence on brain function and mental health is an emerging area of intensive research. Animal and human research indicates adolescence as a sensitive period when the gut-brain axis is fine-tuned, where dietary interventions to change the microbiome may have long-lasting consequences for mental health. 

This study reports a systematic review and meta-analysis of microbiota-targeted (psychobiotics) interventions on anxiety in youth, with discussion of a consultation on the acceptability of psychobiotic interventions for mental health management amongst youth with lived experience. Six databases were searched for controlled trials in human samples (age range: 10-24 years) seeking to reduce anxiety. Post intervention outcomes were extracted as standard mean differences (SMDs) and pooled based on a random-effects model. 5416 studies were identified: 14 eligible for systematic review and 10 eligible for meta-analysis (total of 324 experimental and 293 control subjects). The meta-analysis found heterogeneity I&lt;sup&gt;2&lt;/sup&gt; was 12% and the pooled SMD was -0.03 (95% CI: -0.21, 0.14), indicating an absence of effect. One study presented with low bias risk, 5 with high, and 4 with uncertain risk. Accounting for risk, sensitivities analysis revealed a SMD of -0.16 (95% CI: -0.38, 0.07), indicative of minimal efficacy of psychobiotics for anxiety treatment in humans. 

There is currently limited evidence for use of psychobiotics to treat anxiety in youth. However, future progress will require a multidisciplinary research approach, which gives priority to specifying mechanisms in the human models, providing causal understanding, and addressing the wider context, and would be welcomed by anxious youths.
AN  - 34131108
AU  - Cohen
AU  - Kadosh,
AU  - K.
AU  - Basso,
AU  - M.
AU  - Knytl,
AU  - P.
AU  - Johnstone,
AU  - N.
AU  - Lau,
AU  - J.
AU  - Y.
AU  - F.
AU  - Gibson,
AU  - G.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1038/s41398-021-01422-7
L1  - internal-pdf://0805336047/Cohen Kadosh-2021-Psychobiotic interventions f.pdf
PY  - 2021
SP  - 352
T2  - Transl Psychiatry Psychiatry
TI  - Psychobiotic interventions for anxiety in young people: a systematic review and meta-analysis, with youth consultation
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34131108
UR  - https://www.nature.com/articles/s41398-021-01422-7.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - Micronutrients are fundamental for healthy brain development and deficiencies during early development can have a severe and lasting impact on cognitive outcomes. Evidence indicates that undernourished lactating individuals may produce breast milk containing lower concentrations of certain vitamins and minerals. Exclusively breastfed infants born to mothers deficient in micronutrients may therefore be at risk of micronutrient deficiencies, with potential implications for neurodevelopment. 

This systematic review aims to consider current knowledge on the effects of breast milk micronutrients on the developmental outcomes of infants. The databases Medline, Global Health, PsychInfo, Open Grey, and the Web of Science were searched for papers published before February 2021. Studies were included if they measured micronutrients in breast milk and their association with the neurodevelopmental outcomes of exclusively breastfed infants. Also, randomised control trials investigating neurocognitive outcomes following maternal supplementation during lactation were sought. 

From 5477 initial results, three observational studies were eligible for inclusion. These investigated associations between breast milk levels of vitamin B6, carotenoids, or selenium and infant development. Results presented suggest that pyroxidal, beta-carotene, and lycopene are associated with infant neurodevelopmental outcomes. Limited eligible literature and heterogeneity between included papers prevented quantitative synthesis. Insufficient evidence was identified, precluding any conclusions on the relationship between breast milk micronutrients and infant developmental outcomes. Further, the evidence available was limited by a high risk of bias. 

This highlights the need for further research in this area to understand the long-term influence of micronutrients in breast milk, the role of other breast milk micronutrients in infant neurodevelopmental outcomes, and the impact of possible lactational interventions.
AN  - 34836103
AU  - Lockyer,
AU  - F.
AU  - McCann,
AU  - S.
AU  - Moore,
AU  - S.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/nu13113848
L1  - internal-pdf://2466363704/Breast Milk Micronutrients and Infant Neu-2021.pdf
PY  - 2021
SP  - 28
T2  - Nutrients
TI  - Breast Milk Micronutrients and Infant Neurodevelopmental Outcomes: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34836103
UR  - https://mdpi-res.com/d_attachment/nutrients/nutrients-13-03848/article_deploy/nutrients-13-03848.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - **Background**
The last two decades have seen a significant decrease in mortality for children &lt;5 years of age in low and middle‐income countries (LMICs); however, neonatal (age, 0&ndash;28 days) mortality has not decreased at the same rate. We assessed three neonatal nutritional interventions that have the potential of reducing morbidity and mortality during infancy in LMICs.

**Objectives**
To determine the efficacy and effectiveness of synthetic vitamin A, dextrose oral gel, and probiotic supplementation during the neonatal period.

**Search Methods**
We conducted electronic searches for relevant studies on the following databases: PubMed, CINAHL, LILACS, SCOPUS, and CENTRAL, Cochrane Central Register for Controlled Trials, up to November 27, 2019.

**Selection Criteria**
We aimed to include randomized and quasi‐experimental studies. The target population was neonates in LMICs. The interventions included synthetic vitamin A supplementation, oral dextrose gel supplementation, and probiotic supplementation during the neonatal period. We included studies from the community and hospital settings irrespective of the gestational age or birth weight of the neonate.

**Data Collection and Analysis**
Two authors screened the titles and extracted the data from selected studies. The risk of bias (ROB) in the included studies was assessed according to the Cochrane Handbook of Systematic Reviews. The primary outcome was all‐cause mortality. The secondary outcomes were neonatal sepsis, necrotizing enterocolitis (NEC), prevention and treatment of neonatal hypoglycaemia, adverse events, and neurodevelopmental outcomes. Data were meta‐analyzed by random effect models to obtain relative risk (RR) and 95% confidence interval (CI) for dichotomous outcomes and mean difference with 95% CI for continuous outcomes. The overall rating of evidence was determined by the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach.

**Main Results**
Sixteen randomized studies (total participants 169,366) assessed the effect of vitamin A supplementation during the neonatal period. All studies were conducted in low‐ and middle‐income (LMIC) countries. Thirteen studies were conducted in the community setting and three studies were conducted in the hospital setting, specifically in neonatal intensive care units. Studies were conducted in 10 different countries including India (four studies), Guinea‐Bissau (three studies), Bangladesh (two studies), and one study each in China, Ghana, Indonesia, Nepal, Pakistan, Tanzania, and Zimbabwe. The overall ROB was low in most of the included studies for neonatal vitamin A supplementation. The pooled results from the community based randomized studies showed that there was no significant difference in all‐cause mortality in the vitamin A (intervention) group compared to controls at 1 month (RR, 0.99; 95% CI, 0.90&ndash;1.08; six studies with 126,548 participants, statistical heterogeneity I2 0%, funnel plot symmetrical, grade rating high), 6 months (RR, 0.98; 95% CI, 0.89&ndash;1.07; 12 studies with 154,940 participants, statistical heterogeneity I2 43%, funnel plot symmetrical, GRADE quality high) and 12 months of age (RR, 1.04; 95% CI, 0.94&ndash;1.14; eight studies with 118,376 participants, statistical heterogeneity I2 46%, funnel plot symmetrical, GRADE quality high). Neonatal vitamin A supplementation increased the incidence of bulging fontanelle by 53% compared to control (RR, 1.53; 95% CI, 1.12&ndash;2.09; six studies with 100,256 participants, statistical heterogeneity I2 65%, funnel plot symmetrical, GRADE quality high). We did not identify any experimental study that addressed the use of dextrose gel for the prevention and/or treatment of neonatal hypoglycaemia in LMIC. Thirty‐three studies assessed the effect of probiotic supplementation during the neonatal period (total participants 11,595; probiotics: 5854 and controls: 5741). All of the included studies were conducted in LMIC and were randomized. Most of the studies were done in the hospital setting and included participants who were preterm (born&thinsp;&lt;&thinsp;37 weeks gestation) and/or low birth weight (&lt;2500&thinsp;g birth weight). Studies were conducted in 13 different countries with 10 studies conducted in India, six studies in Turkey, three studies each in China and Iran, two each in Mexico and South Africa, and one each in Bangladesh, Brazil, Colombia, Indonesia, Nepal, Pakistan, and Thailand. Three studies were at high ROB due to lack of appropriate randomization sequence or allocation concealment. Combined data from 25 studies showed that probiotic supplementation reduced all‐cause mortality by 20% compared to controls (RR, 0.80; 95% CI, 0.66&ndash;0.96; total number of participants 10,998, number needed to treat 100, statistical heterogeneity I2 0%, funnel plot symmetrical, GRADE quality high). Twenty‐nine studies reported the effect of probiotics on the incidence of NEC, and the combined results showed a relative reduction of 54% in the intervention group compared to controls (RR, 0.46; 95% CI, 0.35&ndash;0.59; total number of participants 5574, number needed to treat 17, statistical heterogeneity I2 24%, funnel plot symmetrical, GRADE quality high). Twenty‐one studies assessed the effect of probiotic supplementation during the neonatal period on neonatal sepsis, and the combined results showed a relative reduction of 22% in the intervention group compared to controls (RR, 0.78; 95% CI, 0.70&ndash;0.86; total number of participants 9105, number needed to treat 14, statistical heterogeneity I2 23%, funnel plot symmetrical, GRADE quality high).

**Authors&#039; Conclusions**
Vitamin A supplementation during the neonatal period does not reduce all‐cause neonatal or infant mortality in LMICs in the community setting. However, neonatal vitamin A supplementation increases the risk of Bulging Fontanelle. No experimental or quasi‐experimental studies were available from LMICs to assess the effect of dextrose gel supplementation for the prevention or treatment of neonatal hypoglycaemia. Probiotic supplementation during the neonatal period seems to reduce all‐cause mortality, NEC, and sepsis in babies born with low birth weight and/or preterm in the hospital setting. There was clinical heterogeneity in the use of probiotics, and we could not recommend any single strain of probiotics for wider use based on these results. There was a lack of studies on probiotic supplementation in the community setting. More research is needed to assess the effect of probiotics administered to neonates in‐home/community setting in LMICs.
AU  - Imdad,
AU  - A.
AU  - Rehman,
AU  - F.
AU  - Davis,
AU  - E.
AU  - Ranjit,
AU  - D.
AU  - Surin,
AU  - G.
AU  - S.
AU  - S.
AU  - Attia,
AU  - S.
AU  - L.
AU  - Lawler,
AU  - S.
AU  - Smith,
AU  - A.
AU  - A.
AU  - Bhutta,
AU  - Z.
AU  - A.
DA  - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/cl2.1141
L1  - internal-pdf://1642455128/Imdad.pdf
PY  - 2021
T2  - Campbell Systematic Reviews
TI  - Effects of neonatal nutrition interventions on neonatal mortality and child health and development outcomes: A systematic review
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Major depressive disorders have a significant impact on children and adolescents, including on educational and vocational outcomes, interpersonal relationships, and physical and mental health and well-being. There is an association between major depressive disorder and suicidal ideation, suicide attempts, and suicide. Antidepressant medication is used in moderate to severe depression; there is now a range of newer generations of these medications. OBJECTIVES: To investigate, via network meta-analysis (NMA), the comparative effectiveness and safety of different newer generation antidepressants in children and adolescents with a diagnosed major depressive disorder (MDD) in terms of depression, functioning, suicide-related outcomes and other adverse outcomes. The impact of age, treatment duration, baseline severity, and pharmaceutical industry funding was investigated on clinician-rated depression (CDRS-R) and suicide-related outcomes. 

**SEARCH METHODS**: We searched the Cochrane Common Mental Disorders Specialised Register, the Cochrane Library (Central Register of Controlled Trials (CENTRAL) and Cochrane Database of Systematic Reviews (CDSR)), together with Ovid Embase, MEDLINE and PsycINFO till March 2020. SELECTION CRITERIA: Randomised trials of six to 18 year olds of either sex and any ethnicity with clinically diagnosed major depressive disorder were included. Trials that compared the effectiveness of newer generation antidepressants with each other or with a placebo were included. Newer generation antidepressants included: selective serotonin reuptake inhibitors; selective norepinephrine reuptake inhibitors (SNRIs); norepinephrine reuptake inhibitors; norepinephrine dopamine reuptake inhibitors; norepinephrine dopamine disinhibitors (NDDIs); and tetracyclic antidepressants (TeCAs). DATA COLLECTION AND ANALYSIS: Two reviewers independently screened titles/abstracts and full texts, extracted data, and assessed risk of bias. We analysed dichotomous data as Odds Ratios (ORs), and continuous data as Mean Difference (MD) for the following outcomes: depression symptom severity (clinician rated), response or remission of depression symptoms, depression symptom severity (self-rated), functioning, suicide related outcomes and overall adverse outcomes. Random-effects network meta-analyses were conducted in a frequentist framework using multivariate meta-analysis. Certainty of evidence was assessed using Confidence in Network Meta-analysis (CINeMA). We used &quot;informative statements&quot; to standardise the interpretation and description of the results. 

**MAIN RESULTS**: Twenty-six studies were included. There were no data for the two primary outcomes (depressive disorder established via clinical diagnostic interview and suicide), therefore, the results comprise only secondary outcomes. Most antidepressants may be associated with a &quot;small and unimportant&quot; reduction in depression symptoms on the CDRS-R scale (range 17 to 113) compared with placebo (high certainty evidence: paroxetine: MD -1.43, 95% CI -3.90, 1.04; vilazodone: MD -0.84, 95% CI -3.03, 1.35; desvenlafaxine MD -0.07, 95% CI -3.51, 3.36; moderate certainty evidence: sertraline: MD -3.51, 95% CI -6.99, -0.04; fluoxetine: MD -2.84, 95% CI -4.12, -1.56; escitalopram: MD -2.62, 95% CI -5.29, 0.04; low certainty evidence: duloxetine: MD -2.70, 95% CI -5.03, -0.37; vortioxetine: MD 0.60, 95% CI -2.52, 3.72; very low certainty evidence for comparisons between other antidepressants and placebo). There were &quot;small and unimportant&quot; differences between most antidepressants in reduction of depression symptoms (high- or moderate-certainty evidence). Results were similar across other outcomes of benefit. In most studies risk of self-harm or suicide was an exclusion criterion for the study. Proportions of suicide-related outcomes were low for most included studies and 95% confidence intervals were wide for all comparisons. The evidence is very uncertain about the effects of mirtazapine (OR 0.50, 95% CI 0.03, 8.04), duloxetine (OR 1.15, 95% CI 0.72, 1.82), vilazodone (OR 1.01, 95% CI 0.68, 1.48), desvenlafaxine (OR 0.94, 95% CI 0.59, 1.52), citalopram (OR 1.72, 95% CI 0.76, 3.87) or vortioxetine (OR 1.58, 95% CI 0.29, 8.60) on suicide-related outcomes compared with placebo. There is low certainty evidence that escitalopram may &quot;at least slightly&quot; reduce odds of suicide-related outcomes compared with placebo (OR 0.89, 95% CI 0.43, 1.84). There is low certainty evidence that fluoxetine (OR 1.27, 95% CI 0.87, 1.86), paroxetine (OR 1.81, 95% CI 0.85, 3.86), sertraline (OR 3.03, 95% CI 0.60, 15.22), and venlafaxine (OR 13.84, 95% CI 1.79, 106.90) may &quot;at least slightly&quot; increase odds of suicide-related outcomes compared with placebo. There is moderate certainty evidence that venlafaxine probably results in an &quot;at least slightly&quot; increased odds of suicide-related outcomes compared with desvenlafaxine (OR 0.07, 95% CI 0.01, 0.56) and escitalopram (OR 0.06, 95% CI 0.01, 0.56). There was very low certainty evidence regarding other comparisons between antidepressants. 

**AUTHORS&#039; CONCLUSIONS**: Overall, methodological shortcomings of the randomised trials make it difficult to interpret the findings with regard to the efficacy and safety of newer antidepressant medications. Findings suggest that most newer antidepressants may reduce depression symptoms in a small and unimportant way compared with placebo. Furthermore, there are likely to be small and unimportant differences in the reduction of depression symptoms between the majority of antidepressants. However, our findings reflect the average effects of the antidepressants, and given depression is a heterogeneous condition, some individuals may experience a greater response. Guideline developers and others making recommendations might therefore consider whether a recommendation for the use of newer generation antidepressants is warranted for some individuals in some circumstances. Our findings suggest sertraline, escitalopram, duloxetine, as well as fluoxetine (which is currently the only treatment recommended for first-line prescribing) could be considered&nbsp;as a first option. Children and adolescents considered at risk of suicide were frequently excluded from trials, so that we cannot be confident about the effects of these medications for these individuals. If an antidepressant is being considered for an individual, this should be done in consultation with the child/adolescent and their family/caregivers and it remains critical to ensure close monitoring of treatment effects and suicide-related outcomes (combined suicidal ideation and suicide attempt) in those treated with newer generation antidepressants, given findings that some of these medications may be associated with greater odds of these events. Consideration of psychotherapy, particularly cognitive behavioural therapy, as per guideline recommendations, remains important.
AD  - Department of Psychological Medicine, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.Children and Young People Satellite, Cochrane Common Mental Disorders, The University of Auckland, Auckland, New Zealand.School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.Orygen, Parkville, Australia.Centre for Youth Mental Health, The University of Melbourne, Parkville, Australia.Melbourne School of Psychological Sciences, The University of Melbourne, Victoria, Australia.Department of Paediatrics, Monash University, Melbourne, Australia.Department of Psychological Medicine, University of Auckland, Auckland, New Zealand.Centre for Reviews and Dissemination, University of York, York, UK.Cochrane Common Mental Disorders, University of York, York, UK.
AN  - 34029378
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - McKenzie,
AU  - J.
AU  - E.
AU  - Bailey,
AU  - A.
AU  - P.
AU  - Sharma,
AU  - V.
AU  - Moller,
AU  - C.
AU  - I.
AU  - Badcock,
AU  - P.
AU  - B.
AU  - Cox,
AU  - G.
AU  - R.
AU  - Merry,
AU  - S.
AU  - N.
AU  - Meader,
AU  - N.
DA  - May 24
DB  - My EndNote Library.enl
DO  - 10.1002/14651858.CD013674.pub2
DP  - NLM
J2  - The Cochrane database of systematic reviews
KW  - Adolescent
KW  - Antidepressive Agents/adverse effects/*therapeutic use
KW  - Bias
KW  - Child
KW  - Citalopram/therapeutic use
KW  - Depressive Disorder, Major/*drug therapy/psychology
KW  - Desvenlafaxine Succinate/therapeutic use
KW  - Duloxetine Hydrochloride/therapeutic use
KW  - Female
KW  - Fluoxetine/therapeutic use
KW  - Humans
KW  - Male
KW  - Mirtazapine/therapeutic use
KW  - Network Meta-Analysis
KW  - Paroxetine/therapeutic use
KW  - Serotonin Uptake Inhibitors/therapeutic use
KW  - Sertraline/therapeutic use
KW  - Suicidal Ideation
KW  - Venlafaxine Hydrochloride/therapeutic use
KW  - Vilazodone Hydrochloride/therapeutic use
KW  - Vortioxetine/therapeutic use
LA  - eng
N1  - 1469-493xHetrick, Sarah EMcKenzie, Joanne EBailey, Alan PSharma, VartikaMoller, Carl IBadcock, Paul BCox, Georgina RMerry, Sally NMeader, NicholasJournal ArticleMeta-AnalysisResearch Support, Non-U.S. Gov&#039;tSystematic ReviewCochrane Database Syst Rev. 2021 May 24;5(5):CD013674. doi: 10.1002/14651858.CD013674.pub2.
PY  - 2021
SP  - Cd013674
T2  - Cochrane Database Syst Rev
TI  - New generation antidepressants for depression in children and adolescents: a network meta-analysis
VL  - 5
ER  -
TY  - JOUR
AB  - -
AN  - 2015792129
AU  - Alvares,
AU  - M.
AU  - A.
AU  - Serra,
AU  - M.
AU  - J.
AU  - R.
AU  - Delgado,
AU  - I.
AU  - de
AU  - Carvalho,
AU  - J.
AU  - C.
AU  - Sotine,
AU  - T.
AU  - C.
AU  - C.
AU  - Ali,
AU  - Y.
AU  - A.
AU  - de
AU  - Oliveira,
AU  - M.
AU  - R.
AU  - M.
AU  - Rullo,
AU  - V.
AU  - E.
AU  - V.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1590/1806-9282.20210641
L1  - internal-pdf://3057060189/Alvares-2021-Use of probiotics in pediatric pa.pdf
PY  - 2021
SP  - 1503-1507
T2  - Revista da Associacao Medica Brasileira
TI  - Use of probiotics in pediatric patients with autism spectrum disorder: A systematic review
UR  - https://www.scielo.br/j/ramb/a/zBCzzm4Fhf6gfTkgBCCQTgH/?format=pdf&amp;lang=en
UR  - https://www.scielo.br/j/ramb/a/zBCzzm4Fhf6gfTkgBCCQTgH/?lang=en&amp;format=pdf
VL  - 67(10)
ER  -
TY  - JOUR
AB  - Anxious and depressive symptoms are highly prevalent in school-aged youth and can lead to a multitude of negative outcomes. School-based mindfulness interventions may be able to target gaps in evidence-based treatments for anxious and depressive symptoms. 

The current meta-analysis aimed to synthesize the literature of school-based mindfulness interventions that target anxious and depressive symptoms in youth and to compare the effectiveness of these interventions with active and waitlist control groups.

 Overall small significant effect sizes were found for these interventions for both anxious symptoms and depressive symptoms, though they were not significantly different from the aggregated effect sizes of the active control groups or the waitlist control groups, suggesting that mindfulness interventions may not provide additional benefits for these internalizing symptoms. Moderator analyses found that interventions delivered to elementary students yielded significantly higher rates of change than interventions delivered to high school students, but there were no differences when comparing the level or implementer of intervention. 

Overall, the findings of this meta-analysis highlight a critical need to better define what constitutes a &quot;mindfulness intervention&quot; and call into question the effectiveness of those currently being implemented to address youth anxiety and depression in school settings.
AN  - WOS:000740134900001
AU  - Phillips,
AU  - S.
AU  - Mychailyszyn,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12310-021-09492-0
L1  - internal-pdf://1788060870/The Effect of School-Based Mindfulness Interve.pdf
PY  - 2021
SP  - 15
T2  - School Mental Health
TI  - The Effect of School-Based Mindfulness Interventions on Anxious and Depressive Symptoms: A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000740134900001
UR  - https://link.springer.com/content/pdf/10.1007/s12310-021-09492-0.pdf
ER  -
TY  - JOUR
AB  - **Introduction** Comorbid psychiatric conditions in children and adolescents with attention-deficit hyperactivity disorder (ADHD) occur frequently, complicate management, and are associated with substantial burden on patients and caregivers. Very few systematic reviews have assessed the efficacy and safety of medications for ADHD in children and adolescents with comorbidities. Of those that were conducted, most focused on a particular comorbidity or medication. In this systematic literature review, we summarize the efficacy and safety of treatments for children and adolescents with ADHD and comorbid autism spectrum disorders, oppositional defiant disorder, Tourette&#039;s disorder and other tic disorders, generalized anxiety disorder, and major depressive disorder. Methods We searched MEDLINE, Embase, and ClinicalTrials.gov (to October 2019) for studies of patients (aged &lt; 18 years) with an ADHD diagnosis and the specified comorbidities treated with amphetamines, methylphenidate and derivatives, atomoxetine (ATX), and guanfacine extended-release (GXR). For efficacy, placebo-controlled randomized controlled trials (RCTs) or meta-analyses of RCTs were eligible for inclusion; for safety, all study types were eligible. The primary efficacy outcome measure was ADHD Rating Scale IV (ADHD-RS-IV) total score. 

**Results** Of 2177 publications/trials retrieved, 69 were included in this systematic literature review (5 meta-analyses, 37 placebo-controlled RCTs, 16 cohort studies, 11 case reports). A systematic narrative synthesis is provided because insufficient data were retrieved to combine ADHD-RS-IV total scores or effect sizes. Effect sizes for ADHD-RS-IV total scores were available for ten RCTs and ranged from 0.46 to 1.0 for ATX and from 0.92 to 2.0 for GXR across comorbidities. The numbers and types of adverse events in children with comorbidities were consistent with those in children without comorbidities, but treatment should be individualized to ensure children can tolerate the lowest effective dose. 

**Conclusion** Limited information is available from placebo-controlled RCTs on the efficacy (by ADHD-RS-IV) or safety of medication in children with ADHD and psychiatric comorbidities. Further studies are required to support evidence-based drug selection for these populations.
AN  - WOS:000658089400001
AU  - Tsujii,
AU  - N.
AU  - Usami,
AU  - M.
AU  - Naya,
AU  - N.
AU  - Tsuji,
AU  - T.
AU  - Mishima,
AU  - H.
AU  - Horie,
AU  - J.
AU  - Fujiwara,
AU  - M.
AU  - Iida,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40120-021-00249-0
L1  - internal-pdf://0275508581/Tsujii-Efficacy and Safety of Medication for A.pdf
PY  - 2021
SP  - 24
T2  - Neurology and Therapy
TI  - Efficacy and Safety of Medication for Attention-Deficit Hyperactivity Disorder in Children and Adolescents with Common Comorbidities: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000658089400001
UR  - https://link.springer.com/content/pdf/10.1007/s40120-021-00249-0.pdf
ER  -
TY  - JOUR
AB  - Internationally, there is an increasing trend toward placing children in kinship vs. foster care. Prior research suggests that children in kinship care fare better compared to children in foster care; however, the reasons for this remain unclear. 

We conducted a systematic review and meta-analysis to examine the hypothesis that kinship care better preserves children&#039;s connectedness to caregiver, birth family, culture, and community; which, in turn, is associated with more optimal child outcomes. Thirty-one studies were reviewed that compared children aged 0-18 years in kinship care vs. foster care on levels of connectedness, three of which had outcomes that permitted meta-analysis. 

Findings indicated that children in kinship vs. foster care were more likely to feel connected to family in general; however, there was not a clear advantage for kinship vs. foster care for caregiver, birth parent, cultural, and community connectedness. While levels of connectedness were generally associated with more adaptive child outcomes for children in both kinship and foster care, no reviewed studies examined the hypothesis that children&#039;s connectedness may mediate the relationship between placement type and child well-being and placement outcomes.

Results are discussed with respect to limitations and policy implications of the current evidence-base and the need for more rigorous research to help identify how to improve child well-being in home-based care.
AN  - 34114134
AU  - Hassall,
AU  - A.
AU  - Janse
AU  - van
AU  - Rensburg,
AU  - E.
AU  - Trew,
AU  - S.
AU  - Hawes,
AU  - D.
AU  - J.
AU  - Pasalich,
AU  - D.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-021-00352-6
L1  - internal-pdf://3493635236/Hassall-2021-Does Kinship vs. Foster Care Bett.pdf
PY  - 2021
SP  - 10
T2  - Clinical Child &amp; Family Psychology Review
TI  - Does Kinship vs. Foster Care Better Promote Connectedness? A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34114134
UR  - https://link.springer.com/content/pdf/10.1007/s10567-021-00352-6.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and interaction as well as stereotypical and repetitive behavior. Transcranial direct current stimulation (tDCS) has been proposed as a new intervention method in ASD with the potential to improve cognitive, motor and social communication abilities by targeting specific underlying neuronal alterations. Here, we report results of a systematic literature review on tDCS effects on EEG and behavioral outcomes, and discuss tDCS as treatment option for ASD. PsychInfo, PubMed, ScienceDirect, Web of Science, https://clinicaltrials.gov and the German Clinical Trials Register (Deutsches Register Klinischer Studien) were searched systematically for randomized, sham-controlled clinical trials of tDCS in individuals with ASD, and information regarding study designs and relevant results was extracted. Six eligible studies were identified. The dorsolateral prefrontal cortex (DLPFC) was targeted in four trials, with core ASD symptoms and working memory as outcome measures. One study targeted the primary motor cortex (M1) with motor skills as outcome, and one study targeted the temporoparietal junction (TPJ) with social communication skills as outcome measure. Comparison of the implemented study designs showed high methodological variability between studies regarding stimulation parameters, trial design and outcome measures. Study results indicate initial support for improved cognitive and social communication skills in ASD following tDCS stimulation. However, systematic and comparison studies on the best combination of stimulation intensity, duration, location as well as task related stimulation are necessary, before results can be translated into routine clinical application. Copyright &copy; 2021 Elsevier B.V.
AN  - 2011699195
AU  - Luckhardt,
AU  - C.
AU  - Boxhoorn,
AU  - S.
AU  - Schutz,
AU  - M.
AU  - Fann,
AU  - N.
AU  - Freitag,
AU  - C.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/bs.pbr.2021.03.002
L1  - internal-pdf://1734853971/Luckhardt-2021-Brain stimulation by tDCS as tr.pdf
PY  - 2021
SP  - 233-257
T2  - Progress in Brain Research
TI  - Brain stimulation by tDCS as treatment option in Autism Spectrum Disorder-A systematic literature review
UR  - http://www.sciencedirect.com/science/bookseries/00796123
VL  - 264
ER  -
TY  - JOUR
AB  - In the last decades, social-emotional learning interventions have been implemented in schools with the aim of fostering students&#039; non-academic competences. Evaluations of these interventions are essential to assess their potential effects. However, effects may vary depending on students&#039; variables. 

Therefore, the current systematic review had three main objectives: 1) to identify the effectiveness of social-emotional learning interventions with students with special educational needs, 2) to assess and evaluate those intervention conditions leading to effective outcomes in social-emotional competences for this population, and 3) to draw specific conclusions for the population of students with special educational needs. For this purpose, studies were retrieved from the databases Scopus, ERIC, EBSCO and JSTOR, past meta-analysis and (systematic) reviews, as well as from journal hand searches including the years 1994-2020. 

By applying different inclusion criteria, such as implementation site, students&#039; age and study design, a total of eleven studies were eligible for the current systematic review. The primary findings indicate that most of the intervention studies were conducted in the United States and confirm some positive, but primarily small, effects for social-emotional learning interventions for students with special educational needs. Suggestions for future research and practice are made to contribute to the improvement of upcoming intervention studies.
AN  - WOS:000738906800001
AU  - Hassani,
AU  - S.
AU  - Schwab,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/feduc.2021.808566
L1  - internal-pdf://0233019662/Social-Emotional Learning Interventions f-2021.pdf
PY  - 2021
SP  - 19
T2  - Frontiers in Education
TI  - Social-Emotional Learning Interventions for Students With Special Educational Needs: A Systematic Literature Review
UR  - &lt;Go to ISI&gt;://WOS:000738906800001
VL  - 6
ER  -
TY  - JOUR
AB  - Executive functions (EF) and self-regulation (SR) are fundamental for children&#039;s learning, school functioning and academic achievement. EF/SR fail to develop to its full potential if contextual stimulation is not adequately presented. 

This is evident in the training programmes directly and exclusively targeting EF/SR stimulation, which lack durable and transferable effects. Therefore, recent research has shifted the attention towards malleable environmental factors; more specifically, to the role of school and classroom environment as an important developmental context for promoting children&#039;s EF/SR skills and, in turn, their cognition and behaviour.

Numerous observational studies have shown a correlation between the quality of teacher-student relationship (TSR) at the dyadic level or teacher-student interaction (TSI) at the classroom level and children&#039;s EF/SR skills. To explore the direction of this association, the objective of this systematic literature review was to examine the causal effect of experiments and interventions that aim to improve children&#039;s EF/SR by manipulating the TSI. 
Overall, the results from 18 included studies indicated that children in treatment groups show higher gains, albeit small-sized, in EF/SR performance compared to controls. 

Furthermore, TSI manipulation seemed to affect children&#039;s SR skills more strongly than children&#039;s EF skills. More importantly, the findings revealed the largest effects of these manipulations in children considered vulnerable or disadvantaged, suggesting that the cognitive deficits can be minimised if these children are supported appropriately. 

Given high study heterogeneity, this review highlights the need for more research (and interventions) explicitly investigating TSI and TSR and their potential impact on EF and SR in children. 

This study aims to provide information as to which specific aspects need to be examined more closely, instructing further development and implementation of efficient and effective interventions in education.
AN  - 34489822
AU  - Sankalaite,
AU  - S.
AU  - Huizinga,
AU  - M.
AU  - Dewandeleer,
AU  - J.
AU  - Xu,
AU  - C.
AU  - de
AU  - Vries,
AU  - N.
AU  - Hens,
AU  - E.
AU  - Baeyens,
AU  - D.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyg.2021.718262
L1  - internal-pdf://0473249400/Sankalaite-2021-Strengthening Executive Functi.pdf
PY  - 2021
SP  - 718262
T2  - Frontiers in Psychology
TI  - Strengthening Executive Function and Self-Regulation Through Teacher-Student Interaction in Preschool and Primary School Children: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34489822
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417378/pdf/fpsyg-12-718262.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - While prior research has generally found Outdoor Education Programs (OEPs) to be beneficial to adolescents&#039; self-efficacy, we sought to conduct a meta-analytic review of prior studies in this area in order to pinpoint the key elements to OEPs&#039; effectiveness. Following Cooper&#039;s guidelines for synthesis research and meta-analysis, we searched six electronic databases for relevant articles: PubMed, Sciencedirect, Medline, PsycArticles, and Behavioral Sciences Collection of EBSCO, and Eric. Selection criteria were: Populations, Interventions, Comparators, Outcomes, Study Design (PICOS), and Methodological Index for Non-randomized Studies (MINORS). We estimated the effect size of the selected studies with a 95% confidence interval (CI), estimated I-squared (I-2) for heterogeneity analysis and analyzed publication bias by Egger&#039;s test. After excluding many studies, we reviewed 12 studies with 2,642 participants that were deemed to be eligible for final analysis. We discovered a high level of heterogeneity (I-squared value =82.474) in the findings of the selected studies. Our meta-analyses revealed that adolescents participating in OEPs enhanced their self-efficacy (medium effect size; Hedges&#039;s g = 0.597) but this enhancement was moderated by participants&#039; mental health status, the length of the experiments, study groups, and the duration of the intervention. We found no evidence of publication bias (Egger: bias = 2.001, 95% CI = -0.736 to 4.739, p = .137). We discussed our research limitations and the theoretical and practical implications of these findings and made recommendations for future research.
AN  - WOS:000680791200001
AU  - Fang,
AU  - B.
AU  - B.
AU  - Lu,
AU  - F.
AU  - J.
AU  - H.
AU  - Gill,
AU  - D.
AU  - L.
AU  - Liu,
AU  - S.
AU  - A.
AU  - H.
AU  - Chyi,
AU  - T.
AU  - Chen,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/00315125211022709
L1  - internal-pdf://3303510019/Fang-A Systematic Review and Meta-Analysis of.pdf
PY  - 2021
SP  - 27
T2  - Perceptual and Motor Skills
TI  - A Systematic Review and Meta-Analysis of the Effects of Outdoor Education Programs on Adolescents&#039; Self-Efficacy
UR  - &lt;Go to ISI&gt;://WOS:000680791200001
UR  - https://journals.sagepub.com/doi/10.1177/00315125211022709
UR  - https://journals.sagepub.com/doi/pdf/10.1177/00315125211022709
ER  -
TY  - JOUR
AB  - BAKGRUNN
MOT Robust ungdom 12&ndash;16 er et universelt forebyggende og helsefremmende tiltak rettet mot ungdom i alderen 12&ndash;16 år. Målet er å utvikle varmere å tryggere samfunn gjennom å utvikle robuste ungdommer som inkluderer alle. Tiltaket består av tolv klassebesøk over alle årene i ungdomsskolen der ulike tema behandles og gjennomgås etter en fast plan. I tillegg forekommer det andre miljøskapende aktiviteter i løpet av skoleåret. Tiltaket eies av stiftelsen MOT Norge, en idealistisk organisasjon som ble etablert i 1997 av norske toppidrettsutøvere.

METODE
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline, Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket. 

RESULTATER
Resultatene består av en vurdering av tiltakets beskrivelse, foreliggende studier, forskningsmetodisk kvalitet og implementeringskvalitet. MOT-programmet Robust ungdom 12&ndash;16 vurderes som godt beskrevet og det er fundert på allment aksepterte teorier. Det er ikke identifisert noen nordiske effektstudier. I denne kunnskapsoppsummeringen beskrives fire norske studier, men disse er ikke av den vitenskapelige kvalitet som er nødvendig for å kunne si noe sikkert om effekten av tiltaket.

KONKLUSJON
MOT-programmet Robust ungdom 12&ndash;16 klassifiseres på evidensnivå 2 &ndash; Teoretisk begrunnet tiltak.
AU  - Rye,
AU  - M.,
AU  - Kaiser,
AU  - S.,
AU  - Martinussen,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2021
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: MOT-programmet Robust ungdom 12&ndash;16 (1. utg)
UR  - https://ungsinn.no/post_tiltak_arkiv/mot-programmet-robust-ungdom-12-16-1-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - In this review, we summarized and meta-analyzed 35 single-case intervention studies that involved the use of multiple schedules of reinforcement with 78 individuals with intellectual and developmental disabilities. Based on Tau-U calculations, multiple schedules of reinforcement produced an overall large effect for appropriate communicative behavior and an overall moderate effect for challenging behavior. To evaluate variability in study outcomes, we conducted moderator analyses across 21 variables using the Kruskal-Wallis one-way ANOVA test. 

Our findings suggest that the use of response prompts significantly moderated the effects of multiple schedules of reinforcement for appropriate communicative behaviors. We discuss these findings and provide implications for future research and practice.
AD  - Muharib, Reem. Department of Curriculum and Instruction, Texas State University, 601 University Blvd, San Marcos, TX, 78666, USA. r_m806@txstate.edu.Walker, Virginia L. University of North Carolina at Charlotte, Charlotte, NC, USA.Alresheed, Fahad. Easterseals Southern California, Autism Services, Irvine, CA, USA.Gerow, Stephanie. Baylor University, Waco, TX, USA.
AN  - 32592096
AU  - Muharib,
AU  - R.
AU  - Walker,
AU  - V.
AU  - L.
AU  - Alresheed,
AU  - F.
AU  - Gerow,
AU  - S.
DA  - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-020-04569-2
DP  - Ovid Technologies
J2  - J Autism Dev Disord
KW  - Adolescent
KW  - Child
KW  - Child, Preschool
KW  - *Communication
KW  - *Developmental Disabilities/px [Psychology]
KW  - *Developmental Disabilities/th [Therapy]
KW  - Humans
KW  - Male
KW  - *Reinforcement Schedule
KW  - *Reinforcement, Psychology
KW  - Treatment Outcome
KW  - Young Adult
L1  - internal-pdf://1514023148/Muharib-2021.pdf
LA  - English
M3  - Meta-Analysis
Review
N1  - Muharib, ReemWalker, Virginia LAlresheed, FahadGerow, Stephanie
PY  - 2021
SP  - 613-631
T2  - Journal of Autism &amp; Developmental Disorders
TI  - Effects of Multiple Schedules of Reinforcement on Appropriate Communication and Challenging Behaviors: A Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=32592096
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32592096&amp;id=doi:10.1007%2Fs10803-020-04569-2&amp;issn=0162-3257&amp;isbn=&amp;volume=51&amp;issue=2&amp;spage=613&amp;pages=613-631&amp;date=2021&amp;title=Journal+of+Autism+%26+Developmental+Disorders&amp;atitle=Effects+of+Multiple+Schedules+of+Reinforcement+on+Appropriate+Communication+and+Challenging+Behaviors%3A+A+Meta-analysis.&amp;aulast=Muharib&amp;pid=%3Cauthor%3EMuharib+R%3C%2Fauthor%3E%3CAN%3E32592096%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s10803-020-04569-2.pdf
VL  - 51
ER  -
TY  - JOUR
AB  - **INTRODUCTION**
Loneliness is prevalent and associated with negative health outcomes in young people. Our understanding of how it can be best addressed is limited. This systematic review aims to assess the acceptability and effectiveness of interventions to reduce and prevent loneliness and social isolation in young people. 

**METHODS**
Six bibliographic databases were searched; references of included studies were screened for relevant literature. A pre-defined framework was used for data extraction. Quality appraisal was performed using the Mixed Method Appraisal Tool. Data were synthesised narratively. 

**RESULTS**
9,358 unique references were identified; 28 publications from 16 interventions met the inclusion criteria. The majority of interventions were high intensity, individual or small group interventions, often targeted at specific &#039;at risk&#039; populations. While 14 interventions were associated with a statistically significant reduction in loneliness or social isolation, the heterogeneous measures of loneliness, small sample sizes, short periods of follow-up and high attrition rates limit evidence on effectiveness. Interventions implemented in more general populations of young people appeared more acceptable than those in specific &#039;at risk&#039; populations. 

**CONCLUSION**
High intensity interventions are unlikely to be feasible at a population level. Further work is required to develop and evaluate theoretically-informed loneliness interventions for young people that reach wider audiences.
AN  - 34662802
AU  - Osborn,
AU  - T.
AU  - Weatherburn,
AU  - P.
AU  - French,
AU  - R.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.adolescence.2021.09.007
L1  - internal-pdf://1013173773/Osborn-2021-Interventions to address lonelines.pdf
PY  - 2021
SP  - 53-79
T2  - Journal of Adolescence
TI  - Interventions to address loneliness and social isolation in young people: A systematic review of the evidence on acceptability and effectiveness
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34662802
VL  - 93
ER  -
TY  - JOUR
AB  - Body ideals conveyed by the media and by body comparisons often result in body dissatisfaction, which can cause risky health behaviours and eating disorders, especially in adolescents. 

We conducted a meta-analytic review of existing school-based interventions designed to enhance media literacy in order to reduce body dissatisfaction and to promote a positive body image. We included controlled trials examining children and adolescents from grade five to nine (age 10-15 years) after a manual search and a comprehensive literature search using PsycINFO, Medline, Web of Science, and CENTRAL. We computed average weighted effect sizes (Hedges&#039; g) with the help of a random effects model and identified seventeen different programme evaluations with 7392 participants. 

We found a significantly larger effect on positive body image and media literacy in the intervention compared to control groups. However, heterogeneity was substantial for both outcomes. Results suggest that media literacy interventions have the potential to improve media literacy and reduce body dissatisfaction. Interventions that worked with the principle of induction of cognitive dissonance were the most effective.
AN  - 34962632
AU  - Kurz,
AU  - M.
AU  - Rosendahl,
AU  - J.
AU  - Rodeck,
AU  - J.
AU  - Muehleck,
AU  - J.
AU  - Berger,
AU  - U.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10935-021-00660-1
L1  - internal-pdf://2194417415/Kurz-2021-School-Based Interventions Improve B.pdf
PY  - 2021
SP  - 28
T2  - Journal of Primary Prevention
TI  - School-Based Interventions Improve Body Image and Media Literacy in Youth: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34962632
UR  - https://link.springer.com/content/pdf/10.1007/s10935-021-00660-1.pdf
VL  - 28
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
Possible beneficial effects of neurofeedback in improving ADHD functional outcomes have been increasingly reported. This meta-analysis aimed to evaluate the relationship between neurofeedback and executive functioning in children with ADHD. 

**METHODS**
PubMed, EMBASE, EBSCO, Web of Science, and Cochrane databases were searched to identify studies reporting the effects of neurofeedback on executive functioning, including response inhibition, sustained attention, and working memory, assessed by neuropsychological tests. Only randomized controlled studies of children aged 5 to 18 years were included using a random-effects model. 

**RESULTS**
Ten studies were included. The effects of neurofeedback were not found on three domains of executive functions. A meta-regression analysis revealed a trend of numbers of neurofeedback sessions positively associated with response inhibition (p = .06). 

**CONCLUSION**
Results did not show the benefits of neurofeedback on executive functions assessed by neuropsychological tests. Future studies should focus on standard neurofeedback protocols, the intensity of intervention, and neuropsychological outcomes.
AN  - 34697957
AU  - Louthrenoo,
AU  - O.
AU  - Boonchooduang,
AU  - N.
AU  - Likhitweerawong,
AU  - N.
AU  - Charoenkwan,
AU  - K.
AU  - Srisurapanont,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/10870547211045738
L1  - internal-pdf://0446347987/Louthrenoo-2021-The Effects of Neurofeedback o.pdf
PY  - 2021
SP  - 10870547211045738
T2  - Journal of Attention Disorders
TI  - The Effects of Neurofeedback on Executive Functioning in Children With ADHD: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34697957
UR  - https://journals.sagepub.com/doi/pdf/10.1177/10870547211045738
ER  -
TY  - JOUR
AB  - <b>Objective:</b> To identify predictors of medication-placebo differences in double-blind placebo-controlled antidepressant trials in children and adolescents with anxiety and depression. 

<b>Methods:</b> Clinical trials in patients &lt;18 years of age with major depressive disorder or generalized, separation or social anxiety disorders were obtained from PubMed, the Cochrane Database and clinicaltrials.gov searches from inception through 2019. Forty-nine trials (43 published and 6 unpublished) of anxiety (kappa = 13) and depression (kappa = 36) evaluated 19 antidepressants in 8642 child and adolescent patients; placebo and medication response rates, trial characteristics, disorder, medication class, and funding source were extracted. Antidepressant-placebo differences were examined using Bayesian hierarchical models and estimates of response were determined for trial design, disorder, and medication class variables. Using meta-regression, correlates of antidepressant-placebo difference and placebo response were examined. 

<b>Results:</b> Funding source differentiated medication-placebo differences regardless of disorder. Industry trials had larger placebo response rates (mean difference: 0.189 +/- 0.066, credible interval [CrI]: 0.067 to 0.33, p = 0.0008) and smaller medication-placebo differences (-0.235 +/- 0.078, CrI: -0.397 to -0.086, p = 0.005) compared with federally funded trials. However, medication response was similar for industry- and federally-funded studies (-0.046 +/- 0.042, CrI: -0.130 to 0.038, p = 0.252). 

<b>Conclusions:</b> The impact of study sponsorship on trial outcome supports the assertion that industry-funded trials with high placebo response rates and small drug-placebo differences are &quot;failed trials&quot; and should not be described as &quot;negative trials&quot; or used to determine public health estimates of antidepressant efficacy in children and adolescents with anxiety and depression. Identifying the proper role and value of industry-funded trials is critical to establishing the evidence base for antidepressants in youth.
AD  - Mossman, Sarah A. Anxiety Disorders Research Program, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.Mills, Jeffrey A. Department of Economics, Carl H. Lindner College of Business at the University of Cincinnati, Cincinnati, Ohio, USA.Walkup, John T. Department of Psychiatry and Behavioral Health, Robert and Anne Lurie Children&#039;s Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.Strawn, Jeffrey R. Anxiety Disorders Research Program, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
AN  - 33887154
AU  - Mossman,
AU  - S.
AU  - A.
AU  - Mills,
AU  - J.
AU  - A.
AU  - Walkup,
AU  - J.
AU  - T.
AU  - Strawn,
AU  - J.
AU  - R.
DA  - Apr 21
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1089/cap.2020.0195
DP  - Ovid Technologies
J2  - J Child Adolesc Psychopharmacol
L1  - internal-pdf://0036000678/Mossman-2021.pdf
LA  - English
N1  - Using Smart Source ParsingAprMossman, Sarah AMills, Jeffrey AWalkup, John TStrawn, Jeffrey R
PY  - 2021
SP  - 21
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - The Impact of Failed Antidepressant Trials on Outcomes in Children and Adolescents with Anxiety and Depression: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33887154
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33887154&amp;id=doi:10.1089%2Fcap.2020.0195&amp;issn=1044-5463&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+Child+%26+Adolescent+Psychopharmacology&amp;atitle=The+Impact+of+Failed+Antidepressant+Trials+on+Outcomes+in+Children+and+Adolescents+with+Anxiety+and+Depression%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Mossman&amp;pid=%3Cauthor%3EMossman+SA%3C%2Fauthor%3E%3CAN%3E33887154%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.liebertpub.com/doi/10.1089/cap.2020.0195
UR  - https://www.liebertpub.com/doi/pdfplus/10.1089/cap.2020.0195
VL  - 21
ER  -
TY  - JOUR
AB  - The emerging role of a microbiota-gut-brain axis in autism spectrum disorder (ASD) suggests that modulating gut microbial composition may offer a tractable approach to addressing the lifelong challenges of ASD. The aim of this systematic review was to provide an overview and critically evaluate the current evidence on the efficacy and safety of probiotic, prebiotic, synbiotic, and fecal microbiota transplantation therapies for core and co-occurring behavioral symptoms in individuals with ASD. 

Comprehensive searches of MEDLINE, EMBASE, Scopus, Web of Science Core Collection, Cochrane Library, and Google Scholar were performed from inception to March 5, 2020, and two update searches were completed on October 25, 2020, and April 22, 2021, respectively. A total of 4306 publications were identified, of which 14 articles met the inclusion criteria. Data were extracted independently by two reviewers using a preconstructed form. 

Results of probiotic studies do not confirm the supposed beneficial effect of probiotics on ASD, whereas prebiotics and synbiotic combinations appear to be efficacious in selective behavioral symptoms. Evidence of the efficacy of fecal microbiota transplantation in ASD is still scarce but supports further research. Overall, the current evidence base to suggest beneficial effects of these modalities in ASD is limited and inconclusive. More clinical trials are currently looking at the use of microbial-based therapies in ASD. With a robust double-blind randomized controlled protocol to investigate the efficacy, these trials should provide significant and definitive results. 

Lay Summary There is a link between altered gut bacteria and autism spectrum disorder. Some people believe that modulating bacterial composition in the gut may help reduce autism symptoms, but evidence from human studies suggesting beneficial effects of probiotic, prebiotic, and combination thereof as well as fecal transplants in autism spectrum disorder is limited and inconclusive. Current data should not encourage use of these modalities. Further clinical studies are needed.
AN  - WOS:000667848200001
AU  - Tan,
AU  - Q.
AU  - M.
AU  - Orsso,
AU  - C.
AU  - E.
AU  - Deehan,
AU  - E.
AU  - C.
AU  - Kung,
AU  - J.
AU  - I.
AU  - Y.
AU  - Tun,
AU  - H.
AU  - M.
AU  - Wine,
AU  - E.
AU  - Madsen,
AU  - K.
AU  - L.
AU  - Zwaigenbaum,
AU  - L.
AU  - Haqq,
AU  - A.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/aur.2560
L1  - internal-pdf://1130424561/Tan-Probiotics, prebiotics, synbiotics, and fe.pdf
PY  - 2021
SP  - 17
T2  - Autism Research
TI  - Probiotics, prebiotics, synbiotics, and fecal microbiota transplantation in the treatment of behavioral symptoms of autism spectrum disorder: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000667848200001
UR  - https://onlinelibrary.wiley.com/doi/10.1002/aur.2560
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aur.2560?download=true
ER  -
TY  - JOUR
AB  - Approximately half of mothers receiving substance use treatment are involved with childcare proceedings. 

This review aims to determine whether integrated treatment programmes for mothers with substance use problems are effective in preventing out-of-home placement (temporally/permanent) and influencing other maternal factors such as patterns of substance use, treatment completion and parenting behaviours. Six trials were identified-two randomised controlled trials and four non-randomised controlled studies. The pooled sample of participants was 1717. 

The results showed that mothers who participated in integrated treatment programmes were significantly less likely to have the children removed from their care (Odds Ratio (OR) = 0.40, 95% CI = 0.27, 0.61), more likely to complete substance use treatment (OR = 3.01, 95% CI = 1.79, 5.06), and more likely to reduce their alcohol consumption (Standardised Mean Difference (SMD) = -0.40, 95% Cl = -0.78, -0.01) and drug use (SMD = -0.30, 95% CI = -0.53, -0.07). 

However, non-significant reductions were observed for parent-child conflict (SMD = -0.35, 95% CI = -0.72, 0.03) and child abuse risk (SMD = -0.03, 95% CI = -0.36, 0.31). While the findings from this review suggest that mothers involved in integrated treatment programmes could potentially be less likely to experience out-of-home child placements and more likely to improve substance use treatment outcomes, little evidence exists for the effectiveness of these interventions. 

Further research, particularly high-quality RCTs, is required to demonstrate and persuade health and public policy on the far-reaching value of the integrated approaches. 

(PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-87129-001
AU  - Neo,
AU  - S.
AU  - H.
AU  - Norton,
AU  - S.
AU  - Kavallari,
AU  - D.
AU  - Canfield,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s10826-021-02099-8
L1  - internal-pdf://3594529832/Neo-2021-Integrated treatment programmes for m.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Journal of Child and Family Studies
TI  - Integrated treatment programmes for mothers with substance use problems: A systematic review and meta-analysis of interventions to prevent out-of-home child placements
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-87129-001
UR  - https://link.springer.com/content/pdf/10.1007/s10826-021-02099-8.pdf
ER  -
TY  - JOUR
AB  - **PURPOSE**
This meta-analysis aimed to determine the effect of interventions targeting multiple modifiable health behaviors (i.e., physical activity/sedentary behaviors, nutrition/diet, sleep, substance use) on depression and anxiety in young people. **METHODS**
A search of electronic databases from inception until May 2020 was conducted. Randomized controlled trials (RCTs) that explicitly targeted at least two modifiable health behaviors, measured anxiety or depression at baseline and after intervention using a validated instrument, and included participants with an average age between 12 and 25 years were included. The effect of interventions was synthesized using random effects meta-analysis. 
**RESULTS**
A total of 14 RCTs reporting on depression and six RCTs reporting on anxiety were included in the quantitative synthesis. Results showed that although interventions targeting multiple modifiable health behaviors did not produce significant reductions in symptoms of depression (g = -.16, 95% confidence interval [CI] = [-.34, .02], 95% prediction interval [PI] = [-.80, .48], very low certainty evidence) or anxiety (g = -.55, 95% CI = [-1.36, .26], 95% PI = [-3.48, 2.83], very low certainty evidence) across all young people, there was a significant difference in the effect of interventions on depression based on intervention type (Q = 8.37, df = 2, p = .012). Specifically, interventions targeting multiple modifiable health behaviors delivered to groups of young people with an elevated risk of depression had a favorable effect (g = -.28, 95% CI = [-.52, -.05], 95% PI = [-1.04, .47]) on symptoms of depression compared with controls. 

**CONCLUSIONS**
Although not universally effective, this meta-analysis establishes the potential efficacy of targeted interventions aiming to improve multiple modifiable health behaviors to address depression in young people at elevated risk of depression. More research is needed to understand the effect of such interventions on symptoms of anxiety in young people.
AN  - 34580029
AU  - Bourke,
AU  - M.
AU  - Patten,
AU  - R.
AU  - K.
AU  - Dash,
AU  - S.
AU  - Pascoe,
AU  - M.
AU  - Craike,
AU  - M.
AU  - Firth,
AU  - J.
AU  - Bailey,
AU  - A.
AU  - Jacka,
AU  - F.
AU  - Parker,
AU  - A.
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jadohealth.2021.08.005
L1  - internal-pdf://0327425410/Bourke-2021-The Effect of Interventions That T.pdf
PY  - 2021
SP  - 24
T2  - Journal of Adolescent Health
TI  - The Effect of Interventions That Target Multiple Modifiable Health Behaviors on Symptoms of Anxiety and Depression in Young People: A Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34580029
UR  - https://www.jahonline.org/article/S1054-139X(21)00401-8/fulltext
UR  - https://www.jahonline.org/article/S1054-139X(21)00401-8/pdf
VL  - 24
ER  -
TY  - JOUR
AB  - N-3 polyunsaturated fatty acids (PUFAs) have been suggested to affect depressive disorders. This review aims to determine the effect of n-3 PUFAs on depressive symptoms in people with or without diagnosed depression. 

Medline, PsycINFO, and Cochrane CENTRAL databases were searched for randomized controlled trials (RCTs) assessing the association between n-3 PUFAs and depressive symptoms or disorders as outcomes. A random-effects meta-analysis of standardized mean difference (SMD) with 95% confidence intervals (CI) was performed. 

Twenty-five studies (7682 participants) were included. Our meta-analysis (20 studies) indicated that n-3 PUFA supplementation lowered depressive symptomology as compared with placebo: SMD = -0.34, 95% CI: -0.55, -0.12, I&lt;sup&gt;2&lt;/sup&gt; = 86%, n = 5836, but a possible publication bias cannot be ruled out. Subgroup analyses indicated no statistically significant difference by treatment duration of &lt;12 vs. &gt;=12 weeks, presence of comorbidity, or severity of depressive symptoms. Nevertheless, beneficial effects were seen in the subgroups of studies with longer treatment duration and with no depression and mild to moderate depression. Subgroup analysis by eicosapentaenoic acid (EPA) dosage revealed differences in favor of the lower EPA dosage. Sensitivity analysis including studies with low risk of bias seems to confirm the overall result. Supplementation of n-3 PUFA appears to have a modest beneficial effect on depressive symptomology, although the quality of evidence is still insufficient. Copyright &copy; 2021 by the authors. Licensee MDPI, Basel, Switzerland.
AN  - 2006808108
AU  - Wolters,
AU  - M.
AU  - von
AU  - der
AU  - Haar,
AU  - A.
AU  - Baalmann,
AU  - A.
AU  - K.
AU  - Wellbrock,
AU  - M.
AU  - Heise,
AU  - T.
AU  - L.
AU  - Rach,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/nu13041070
L1  - internal-pdf://4260950880/Wolters-2021-Effects of n-3 polyunsaturated fa.pdf
PY  - 2021
T2  - Nutrients
TI  - Effects of n-3 polyunsaturated fatty acid supplementation in the prevention and treatment of depressive disorders- a systematic review and meta-analysis
UR  - https://www.mdpi.com/2072-6643/13/4/1070
UR  - https://res.mdpi.com/d_attachment/nutrients/nutrients-13-01070/article_deploy/nutrients-13-01070-v3.pdf
VL  - 13 (4) (no pagination)
ER  -
TY  - JOUR
AB  - **Background**
The therapeutic effect of bumetanide on autism spectrum disorder (ASD) seems to be controversial. To obtain better evidence on the efficacy of bumetanide, a systematic review and meta-analysis were performed.
AN  - 34867539
AU  - Wang,
AU  - T.
AU  - Shan,
AU  - L.
AU  - Miao,
AU  - C.
AU  - Xu,
AU  - Z.
AU  - Jia,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2021.751575
L1  - internal-pdf://2192650646/fpsyt-12-751575.cleaned.pdf
PY  - 2021
SP  - 751575
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Treatment Effect of Bumetanide in Children With Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34867539
VL  - 12
ER  -
TY  - JOUR
AB  - **Background**: There is evidence that repetitive transcranial magnetic stimulation (rTMS) is effective for treating adult depression. However, it remains unclear whether rTMS is an effective treatment for adolescent depression. This systematic review examines the existing literature on the effectiveness and acceptability of rTMS in the treatment of adolescent depression. 

**Methods**: After protocol registration (PROSPERO), we searched PubMed, Embase, PsycINFO, WoS and CENTRAL databases and the grey literature. We included studies that used rTMS in adolescents aged 12-25 years old who had a clinical diagnosis of depression. Study quality was assessed using the Newcastle-Ottawa Scale. 

**Results**: Fourteen studies were identified, which included 8 open-trial studies (N = 142 participants) and six studies which performed further post-hoc/follow-up analyses on these open-trial datasets. All studies suffered from multiple biases but reported that rTMS treatment reduced depression scores in adolescents. A single study on theta burst stimulation also found a positive effect. No study to date includes a sham control. Reported side effects of rTMS included scalp pain, headache and dizziness. Limitations: Study methodologies precluded a meta-analysis. 

**Conclusions**: The current literature signals that rTMS could reduce adolescent depressive symptoms. However, sham controlled randomized trials are needed. These findings suggest that rTMS may be a promising treatment option for adolescents with depression. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Hett, Danielle: D.Hett@bham.ac.ukHett, Danielle: Institute for Mental Health, University of Birmingham, Edgbaston, Birmingham, United Kingdom, B15 2TT, D.Hett@bham.ac.ukHett, Danielle: Institute for Mental Health, University of Birmingham, Birmingham, United KingdomRogers, Jack: Institute for Mental Health, University of Birmingham, Birmingham, United KingdomHumpston, Clara: Institute for Mental Health, University of Birmingham, Birmingham, United KingdomMarwaha, Steven: Institute for Mental Health, University of Birmingham, Birmingham, United Kingdom
AN  - 2020-91544-061
AU  - Hett,
AU  - D.
AU  - Rogers,
AU  - J.
AU  - Humpston,
AU  - C.
AU  - Marwaha,
AU  - S.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2020.09.058
DP  - Ovid Technologies
KW  - Depression, Repetitive transcranial magnetic stimulation, Rtms, Adolescents, Systematic review
KW  - *Adolescent Psychiatry
KW  - *Major Depression
KW  - *Transcranial Magnetic Stimulation
KW  - Specialized Interventions [3350]
KW  - Human Adolescence (13-17 yrs)
L1  - internal-pdf://2497911037/Hett-2021.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2021
SP  - 460-469
T2  - Journal of Affective Disorders
TI  - Repetitive transcranial magnetic stimulation (rTMS) for the treatment of depression in adolescence: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-91544-061
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jad.2020.09.058&amp;issn=0165-0327&amp;isbn=&amp;volume=278&amp;issue=&amp;spage=460&amp;pages=460-469&amp;date=2021&amp;title=Journal+of+Affective+Disorders&amp;atitle=Repetitive+transcranial+magnetic+stimulation+%28rTMS%29+for+the+treatment+of+depression+in+adolescence%3A+A+systematic+review.&amp;aulast=Hett&amp;pid=%3Cauthor%3EHett%2C+Danielle%3C%2Fauthor%3E%3CAN%3E2020-91544-061%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 278
ER  -
TY  - JOUR
AB  - **ABSTRACT**: Chronic pain in childhood is an international public health problem. We conducted a systematic review and meta-analysis to provide a summary of the published evidence of pharmacological, physical, and psychological therapies for children with chronic pain conditions. We searched CENTRAL, MEDLINE, EMBASE, and PsycINFO from inception to April 2020, clinical trial registries, and other sources for randomised controlled trials or comparative observational trials. We extracted critical outcomes of pain intensity, quality of life, physical-, role-, and emotional functioning, sleep, and adverse events. We assessed studies for risk of bias and certainty of the evidence using GRADE. We included 34 pharmacological (4091 participants), 25 physical therapy (1470 participants), and 63 psychological trials (5025 participants). Participants reported a range of chronic pain conditions. Most studies were assessed to have unclear or high risk of bias across multiple domains. Pharmacological, physical, and psychological therapies showed some benefit for reducing pain, post-treatment but only physical and psychological therapies improved physical functioning. We found no benefit of any treatment modality for health-related quality of life, role functioning, emotional functioning, or sleep. Adverse events were poorly reported particularly for psychological and physical interventions. The largest evidence-base for the management of chronic pain in children supports the use of psychological therapies, followed by pharmacological and physical therapies. However, we rated most outcomes as low or very low-certainty, meaning further evidence is likely to change our confidence in the estimates of effects. This protocol was registered on PROSPERO (CRD42020172451).
AD  - Fisher, Emma. Centre for Pain Research, University of Bath, UK Cochrane Pain, Palliative and Supportive Care Review Group, Oxford, UK Cochrane Response, London, UK Department of Biostatistics, University of Liverpool, Liverpool UK Division of Pain and Palliative Medicine, Connecticut Children&#039;s Medical Center, Department of Pediatrics, University of Connecticut School of Medicine, Hartford, CT, USA Cochrane Kidney and Transplant, Centre for Kidney Research, Children&#039;s Hospital at Westmead, Australia Sydney School of Public Health, The University of Sydney, Australia Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children&#039;s Hospital, Boston, USA. Department of Anesthesiology, Harvard Medical School, Boston, USA. Department of Experimental-Clinical and Health Psychology, Ghent University, Belgium.
AN  - 33883536
AU  - Fisher,
AU  - E.
AU  - Villanueva,
AU  - G.
AU  - Henschke,
AU  - N.
AU  - Nevitt,
AU  - S.
AU  - J.
AU  - Zempsky,
AU  - W.
AU  - Probyn,
AU  - K.
AU  - Buckley,
AU  - B.
AU  - Cooper,
AU  - T.
AU  - E.
AU  - Sethna,
AU  - N.
AU  - Eccleston,
AU  - C.
DA  - Apr 19
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/j.pain.0000000000002297
DP  - Ovid Technologies
J2  - Pain
L1  - internal-pdf://3602391106/Fisher-2021.pdf
LA  - English
N1  - Using Smart Source ParsingAprFisher, EmmaVillanueva, GemmaHenschke, NicholasNevitt, Sarah JZempsky, WilliamProbyn, KatrinBuckley, BrianCooper, Tess ESethna, NavilEccleston, Christopher
PY  - 2021
SP  - 19
T2  - Pain
TI  - Efficacy and safety of pharmacological, physical, and psychological interventions for the management of chronic pain in children: a WHO systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33883536
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33883536&amp;id=doi:10.1097%2Fj.pain.0000000000002297&amp;issn=0304-3959&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Pain&amp;atitle=Efficacy+and+safety+of+pharmacological%2C+physical%2C+and+psychological+interventions+for+the+management+of+chronic+pain+in+children%3A+a+WHO+systematic+review+and+meta-analysis.&amp;aulast=Fisher&amp;pid=%3Cauthor%3EFisher+E%3C%2Fauthor%3E%3CAN%3E33883536%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 19
ER  -
TY  - JOUR
AB  - Personalized Normative Feedback (PNF) may help address addictive disorders. PNF highlights discrepancies between perceived and actual peer norms, juxtaposed against self-reported behavior. PNF can be self-directed and cost-efficient. Our study estimates the efficacy of PNF alone, and in combination with other self-directed interventions, to address frequency and symptom severity of hazardous alcohol use, problem gambling, illicit drug and tobacco use. We searched electronic databases, grey literature, and reference lists of included articles, for randomized controlled trials published in English (January 2000-August 2019). We assessed study quality using the Cochrane Risk of Bias tool. Thirty-four studies met inclusion criteria (k = 28 alcohol, k = 3 gambling, k = 3 cannabis, k = 0 tobacco). Thirty studies provided suitable data for meta-analyses. PNF alone, and with additional interventions, reduced short-term alcohol frequency and symptom severity. PNF with additional interventions reduced short-term gambling symptom severity. Effect sizes were small. PNF did not alter illicit drug use. Findings highlight the efficacy of PNF to address alcohol frequency and symptom severity. The limited number of studies suggest further research is needed to ascertain the efficacy of PNF for gambling and illicit drug use. Cost-effectiveness analyses are required to determine the scale of PNF needed to justify its use in various settings. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2021-33833-001
AU  - Saxton,
AU  - J.
AU  - Rodda,
AU  - S.
AU  - Booth,
AU  - N.
AU  - Merkouris,
AU  - S.
AU  - Dowling,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - Tom verdi
L1  - internal-pdf://3051451600/The efficacy of Personalized Normative Fe-2021.pdf
PY  - 2021
T2  - PLoS ONE Vol 16(4), 2021, ArtID e0248262
TI  - The efficacy of Personalized Normative Feedback interventions across addictions: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2021-33833-001
VL  - 16
ER  -
TY  - JOUR
AB  - <b>Background:</b> Early comprehensive treatment models (CTMs) have been developed as effective treatments for children with autism spectrum disorder (ASD). Numerous studies have suggested that CTMs can improve short-term outcomes, but little is known about precise outcome information in childhood. The current meta-analysis reviewed studies reporting broader outcomes in children with ASD who had ever participated in a CTM and examined the predictors of developmental gains.
AN  - 34381389
AU  - Shi,
AU  - B.
AU  - Wu,
AU  - W.
AU  - Dai,
AU  - M.
AU  - Zeng,
AU  - J.
AU  - Luo,
AU  - J.
AU  - Cai,
AU  - L.
AU  - Wan,
AU  - B.
AU  - Jing,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2021.691148
L1  - internal-pdf://0168184938/Shi-2021-Cognitive, Language, and Behavioral O.pdf
PY  - 2021
SP  - 691148
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Cognitive, Language, and Behavioral Outcomes in Children With Autism Spectrum Disorders Exposed to Early Comprehensive Treatment Models: A Meta-Analysis and Meta-Regression
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34381389
VL  - 12
ER  -
TY  - JOUR
AB  - **Background**: Anxiety disorder is the most prevalent mental disorder in children and adolescents. However, evidence for efficacy and acceptability between individual cognitive behavior therapy (I-CBT) and group cognitive behavior therapy (G-CBT) in anxiety disorders in children and adolescents remains unclear.

**Methods**: Eight electronic databases (PubMed, Embase, Cochrane, Web of Science, CINAHL, PsycINFO, ProQuest, and LILACS) were searched from inception to October 2019. Randomized controlled trials comparing I-CBT with G-CBT for anxiety disorders in children and adolescents were included. The primary outcomes were efficacy (mean change in anxiety symptom scores) at post-treatment and acceptability (all-cause discontinuation). The secondary outcome was remission at post-treatment. Subgroup analyses were also conducted to examine whether the result would be influenced by age, number of treatment sessions, parental involvement, male/female sex, and number of participants.

**Results**: Nine studies were selected in this meta-analysis. The pooled analyses indicated no significant difference between I-CBT and G-CBT for efficacy at post-treatment [standardized mean difference (SMD), &minus;0.14; 95% confidence interval (CI), &minus;0.37 to 0.09], acceptability [odds ratio (OR), 1.30; 95% CI, 0.61&ndash;2.77], and remission at post-treatment (OR, 1.15; 95% CI, 0.79&ndash;1.66). In the subgroup analysis of age, I-CBT was significantly more effective than G-CBT in adolescents at post-treatment (SMD, &minus;0.77; 95% CI, &minus;1.51 to &minus;0.02), but not in children (SMD, 0.00; 95% CI, &minus;0.02 to 0.20). However, the findings were not materially different from those of the efficacy subgroup analysis of number of treatment sessions, parental involvement, male/female sex, and number of participants.

**Conclusions**: Based on those current evidence, I-CBT was shown to be more beneficial than G-CBT for anxiety disorders in adolescents, but not in children. However, further well-designed clinical studies should be performed to confirm these findings.
AN  - 34744809
AU  - Guo,
AU  - T.
AU  - Su,
AU  - J.
AU  - Hu,
AU  - J.
AU  - Aalberg,
AU  - M.
AU  - Zhu,
AU  - Y.
AU  - Teng,
AU  - T.
AU  - Zhou,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2021.674267
L1  - internal-pdf://3853890131/Guo-2021.pdf
PY  - 2021
SP  - 674267
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Individual vs. Group Cognitive Behavior Therapy for Anxiety Disorder in Children and Adolescents: A Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34744809
VL  - 12
ER  -
TY  - JOUR
AB  - INTRODUCTION: . Children with Autism Spectrum Disorder (ASD) experience difficulties in Executive Functions (EF) performances. However, efficacy of EF intervention needs to be further investigated. OBJECTIVE: to evaluate the efficacy of different EF interventions in children and adolescents with ASD. 

METHODS: A systematic review and meta-analysis were carried out according to PRISMA guidelines. Relevant databases including Pubmed, Psychinfo, Scopus and Web of Science were searched up to November 2019. Papers included in the study have the following characteristics: randomized controlled trial or quasi-experimental design and be published in English or Spanish. 

RESULTS: After the elimination of duplicates, 949 were screened. Among these six were included in the systematic review. The main approaches for EF in ASD were computer-based interventions, cognitive-behavioral therapy and assisted-animal therapy. Statistically significant results (p=0.003) were found in using exergames. 

CONCLUSION: Different approaches can be used for improving EF intervention, with positive effects on working memory, behavior, and flexibility.
AN  - 34821185
AU  - Cavalli,
AU  - G.
AU  - Galeoto,
AU  - G.
AU  - Sogos,
AU  - C.
AU  - Berardi,
AU  - A.
AU  - Tofani,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/14737175.2022.2011215
L1  - internal-pdf://2472976419/Cavalli-2021.pdf
PY  - 2021
SP  - 25
T2  - Expert Review of Neurotherapeutics
TI  - The Efficacy of Executive Function interventions in children with Autism Spectrum Disorder: a Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34821185
UR  - https://www.tandfonline.com/doi/full/10.1080/14737175.2022.2011215
VL  - 25
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
To strengthen the impact of cash transfers, these interventions have begun to be packaged as cash-plus programmes, combining cash with additional transfers, interventions, or services. The intervention&#039;s complementary (&quot;plus&quot;) components aim to improve cash transfer effectiveness by targeting mediating outcomes or the availability of supplies or services. This study examined whether cash-plus interventions for infants and children &lt;5 are more effective than cash alone in improving health and well-being. 

**METHODS AND FINDINGS: **
Forty-two databases, donor agencies, grey literature sources, and trial registries were systematically searched, yielding 5,097 unique articles (as of 06 April 2021). Randomised and quasi-experimental studies were eligible for inclusion if the intervention package aimed to improve outcomes for children &lt;5 in low- and middle-income countries (LMICs) and combined a cash transfer with an intervention targeted to Sustainable Development Goal (SDG) 2 (No Hunger), SDG3 (Good Health and Well-being), SDG4 (Education), or SDG16 (Violence Prevention), had at least one group receiving cash-only, examined outcomes related to child-focused SDGs, and was published in English. 
Risk of bias was appraised using Cochrane Risk of Bias and ROBINS-I Tools. Random effects meta-analyses were conducted for a cash-plus intervention category when there were at least 3 trials with the same outcome. 
The review was preregistered with PROSPERO (CRD42018108017). 

Seventeen studies were included in the review and 11 meta-analysed. Most interventions operated during the first 1,000 days of the child&#039;s life and were conducted in communities facing high rates of poverty and often, food insecurity. Evidence was found for 10 LMICs, where most researchers used randomised, longitudinal study designs (n = 14). Five intervention categories were identified, combining cash with nutrition behaviour change communication (BCC, n = 7), food transfers (n = 3), primary healthcare (n = 2), psychosocial stimulation (n = 7), and child protection (n = 4) interventions. Comparing cash-plus to cash alone, meta-analysis results suggest Cash + Food Transfers are more effective in improving height-for-age (d = 0.08 SD (0.03, 0.14), p = 0.02) with significantly reduced odds of stunting (OR = 0.82 (0.74, 0.92), p = 0.01), but had no added impact in improving weight-for-height (d = -0.13 (-0.42, 0.16), p = 0.24) or weight-for-age z-scores (d = -0.06 (-0.28, 0.15), p = 0.43). 

There was no added impact above cash alone from Cash + Nutrition BCC on anthropometrics; Cash + Psychosocial Stimulation on cognitive development; or Cash + Child Protection on parental use of violent discipline or exclusive positive parenting. Narrative synthesis evidence suggests that compared to cash alone, Cash + Primary Healthcare may have greater impacts in reducing mortality and Cash + Food Transfers in preventing acute malnutrition in crisis contexts. The main limitations of this review are the few numbers of studies that compared cash-plus interventions against cash alone and the potentially high heterogeneity between study findings. 

**CONCLUSIONS: **
In this study, we observed that few cash-plus combinations were more effective than cash transfers alone. Cash combined with food transfers and primary healthcare show the greatest signs of added effectiveness. More research is needed on when and how cash-plus combinations are more effective than cash alone, and work in this field must ensure that these interventions improve outcomes among the most vulnerable children.
AN  - 34582447
AU  - Little,
AU  - M.
AU  - T.
AU  - Roelen,
AU  - K.
AU  - Lange,
AU  - B.
AU  - C.
AU  - L.
AU  - Steinert,
AU  - J.
AU  - I.
AU  - Yakubovich,
AU  - A.
AU  - R.
AU  - Cluver,
AU  - L.
AU  - Humphreys,
AU  - D.
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1371/journal.pmed.1003698
L1  - internal-pdf://2471569690/Little-2021-Effectiveness of cash-plus program.pdf
PY  - 2021
SP  - e1003698
T2  - PLoS Medicine / Public Library of Science
TI  - Effectiveness of cash-plus programmes on early childhood outcomes compared to cash transfers alone: A systematic review and meta-analysis in low- and middle-income countries
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34582447
UR  - https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pmed.1003698/1/pmed.1003698.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&amp;X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20211008%2Fauto%2Fstorage%2Fgoog4_request&amp;X-Goog-Date=20211008T135321Z&amp;X-Goog-Expires=86400&amp;X-Goog-SignedHeaders=host&amp;X-Goog-Signature=98419fc87718c2127ead9145cc7d7b770f794e5823cee0615e1833f3fa4998aa79baeb1cf572ff9315b4dde7816a60c11042ff2d793896ea7cb49fcad3fd43e5bf0dca494f3e2d4b9fa03bd6562a541a853fb674f44a011cab9a7d1ec62e985ae555a1cd9c5d8606df00328ff6ee037a632a578b3c0c31b3ed3535c3c4447ca8b9eadc807523f767f1f079a56e676935e19be6e287fb1d4ddba463048f863583f6ffb07730541ad2e7733c43a787a16b9580a8c6fb6c9aac126a9760095b3c459c323b2e351bc549ede64cc132f66dc3df2c4e935b19444bd0d9f4b200da21fa274245acc246f2db5a97ee924c1bf7f2b16c865126f413ca37f8e4b4654c42c3
VL  - 18
ER  -
TY  - JOUR
AB  - Based on epidemiological and animal studies, the rationale for using polyunsaturated fatty acids (PUFAs) as a treatment for Attention Deficit Hyperactivity Disorder (ADHD) seems promising. 

Here, the objective was to systematically identify and critically assess the evidence from clinical trials. The primary outcome was ADHD core symptoms. The secondary outcomes were behavioral difficulties, quality of life, and side effects. 

We performed a systematic search in Medline, Embase, Cinahl, PsycInfo, and the Cochrane Library up to June 2020. The overall certainty of evidence was evaluated using Grades of Recommendation, Assessment, Development, and Evaluation (GRADE). We identified 31 relevant randomized controlled trials including 1755 patients. 

The results showed no effect on ADHD core symptoms rated by parents (k = 23; SMD: -0.17; 95% CI: -0.32, -0.02) or teachers (k = 10; SMD: -0.06; 95% CI: -0.31, 0.19). There was no effect on behavioral difficulties, rated by parents (k = 7; SMD: -0.02; 95% CI: -0.17, 0.14) or teachers (k = 5; SMD: -0.04; 95% CI: -0.35, 0.26). There was no effect on quality of life (SMD: 0.01; 95% CI: -0.29, 0.31). PUFA did not increase the occurrence of side effects. 

For now, there seems to be no benefit of PUFA in ADHD treatment; however, the certainty of evidence is questionable, and thus no conclusive guidance can be made. The protocol is registered in PROSPERO ID: CRD42020158453. Copyright &copy; 2021 by the authors. Licensee MDPI, Basel, Switzerland.
AD  - (Handel, Rohde, Bandak) The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg 2000, Denmark (Handel, Rohde, Bandak, Birkefoss, Tendal, Callesen) The Danish Health Authority, Copenhagen 2300, Denmark (Rimestad) Institute of Psychology, Aarhus University, Aarhus 8000, Denmark (Lemcke) Department of Child and Adolescent Psychiatry, Aarhus University Hospital, 8200 Aarhus N, Psychiatry, DenmarkM.N. Handel, The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region, Frederiksberg 2000, Denmark. E-mail: mina.nicole.holmgaard.handel@regionh.dk M.N. Handel, The Danish Health Authority, Copenhagen 2300, Denmark. E-mail: mina.nicole.holmgaard.handel@regionh.dk
AN  - 2006907133
AU  - Handel,
AU  - M.
AU  - N.
AU  - Rohde,
AU  - J.
AU  - F.
AU  - Rimestad,
AU  - M.
AU  - L.
AU  - Bandak,
AU  - E.
AU  - Birkefoss,
AU  - K.
AU  - Tendal,
AU  - B.
AU  - Lemcke,
AU  - S.
AU  - Callesen,
AU  - H.
AU  - E.
DA  - April
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/nu13041226
DP  - Ovid Technologies
KW  - adhd
KW  - Adolescents
KW  - Attention deficit hyperactivity disorder
KW  - Children
KW  - Fatty acids
KW  - Meta-analysis
KW  - Omega 3
KW  - Polyunsaturated
KW  - Systematic review
KW  - adolescent
KW  - attention deficit disorder/dt [Drug Therapy]
KW  - child
KW  - Cinahl
KW  - Cochrane Library
KW  - diarrhea/si [Side Effect]
KW  - Embase
KW  - gastrointestinal symptom/si [Side Effect]
KW  - human
KW  - information retrieval
KW  - Medline
KW  - meta analysis
KW  - nausea/si [Side Effect]
KW  - outcome assessment
KW  - parent
KW  - PsycINFO
KW  - quality of life
KW  - randomized controlled trial (topic)
KW  - review
KW  - side effect
KW  - supplementation
KW  - teacher
KW  - omega 3 fatty acid/ae [Adverse Drug Reaction]
KW  - omega 3 fatty acid/cm [Drug Comparison]
KW  - omega 3 fatty acid/dt [Drug Therapy]
KW  - omega 6 fatty acid/ae [Adverse Drug Reaction]
KW  - omega 6 fatty acid/cm [Drug Comparison]
KW  - omega 6 fatty acid/dt [Drug Therapy]
KW  - placebo
L1  - internal-pdf://4010089608/Handel-2021.pdf
LA  - English
M3  - Review
PY  - 2021
T2  - Nutrients
TI  - Efficacy and safety of polyunsaturated fatty acids supplementation in the treatment of attention deficit hyperactivity disorder (Adhd) in children and adolescents: A systematic review and meta-analysis of clinical trials
UR  - https://www.mdpi.com/2072-6643/13/4/1226/pdf
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2006907133
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.3390%2Fnu13041226&amp;issn=2072-6643&amp;isbn=&amp;volume=13&amp;issue=4&amp;spage=1226&amp;pages=&amp;date=2021&amp;title=Nutrients&amp;atitle=Efficacy+and+safety+of+polyunsaturated+fatty+acids+supplementation+in+the+treatment+of+attention+deficit+hyperactivity+disorder+%28Adhd%29+in+children+and+adolescents%3A+A+systematic+review+and+meta-analysis+of+clinical+trials&amp;aulast=Handel&amp;pid=%3Cauthor%3EHandel+M.N.%3C%2Fauthor%3E%3CAN%3E2006907133%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://res.mdpi.com/d_attachment/nutrients/nutrients-13-01226/article_deploy/nutrients-13-01226.pdf
VL  - 13 (4) (no pagination)
ER  -
TY  - JOUR
AB  - This review aimed to identify and evaluate interventions that have the potential to foster engaged fathering to enhance children&#039;s health and development. 

Relevant articles published in the last 20 years were searched in Medline, CINAHL, PsycINFO, Cochrane Database of Systematic Reviews and Web of Science databases. The quality of studies was assessed independently by two reviewers using the Joanna Briggs Institute (JBI) Critical Appraisal Checklists. 

Thirty out of 3968 articles met the inclusion criteria and were subsequently reviewed. Studies were conducted in six countries (USA, Australia, Canada, Germany, Vietnam and Taiwan). Twenty-one studies were targeted interventions while nine were universal interventions. The interventions involved parenting education, physical activity, nutrition, father-child socialization, father delivered infant massage and father-infant skin-to-skin contact. 

Authors of the studies reported that the interventions led to significant improvements in positive parenting behaviours and fathers&#039; engagement with their children and better physical health and developmental outcomes among children. Notwithstanding the reported benefits of the interventions, all 30 studies had one or more methodological problems that call in question the generalizability of the findings. Future, well-designed, RCT studies with larger sample sizes and clear measures of fidelity are warranted to replicate and strengthen findings reported in this review. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-19178-001
AU  - Kalembo,
AU  - F.
AU  - W.
AU  - Kendall,
AU  - G.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/cfs.12897
L1  - internal-pdf://3131218752/A systematic review of interventions that-2021.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Child &amp; Family Social Work
TI  - A systematic review of interventions that have the potential to foster engaged fathering to enhance children&#039;s health and development
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-19178-001
UR  - https://onlinelibrary.wiley.com/doi/10.1111/cfs.12897
ER  -
TY  - JOUR
AB  - **Background** Preterm and low birth weight infants are born with low stores in zinc, which is a vital trace element for growth, cell differentiation and immune function. Preterm infants are at risk of zinc deficiency during the postnatal period of rapid growth. Systematic reviews in the older paediatric population have previously shown that zinc supplementation potentially improves growth and positively influences the course of infectious diseases. In paediatric reviews, the effect of zinc supplementation was most pronounced in those with low nutritional status, which is why the intervention could also benefit preterm infants typically born with low zinc stores and decreased immunity.

**Objectives** To determine whether enteral zinc supplementation, compared with placebo or no supplementation, affects important outcomes in preterm infants, including death, neurodevelopment, common morbidities and growth.

**Search methods** Our searches are up‐to‐date to 20 February 2020. For the first search, we used the standard search strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL 2017, Issue 8), MEDLINE via PubMed (1966 to 29 September 2017), Embase (1980 to 29 September 2017), and CINAHL (1982 to 29 September 2017). We also searched clinical trials databases, conference proceedings, and the reference lists of retrieved articles for randomised controlled trials (RCTs) and quasi‐RCTs. We ran an updated search from 1 January 2017 to 20 February 2020 in the following databases: CENTRAL via CRS Web, MEDLINE via Ovid, and CINAHL via EBSCOhost.

**Selection criteria** We included RCTs and quasi‐RCTs that compared enteral zinc supplementation versus placebo or no supplementation in preterm infants (gestational age &lt; 37 weeks), and low birth weight babies (birth weight &lt; 2500 grams), at any time during their hospital admission after birth. We included zinc supplementation in any formulation, regimen, or dose administered via the enteral route. We excluded infants who underwent gastrointestinal (GI) surgery during their initial hospital stay, or had a GI malformation or another condition accompanied by abnormal losses of GI juices, which contain high levels of zinc (including, but not limited to, stomas, fistulas, and malabsorptive diarrhoea).

**Data collection and analysis** We used the standard methods of Cochrane Neonatal. Two review authors separately screened abstracts, evaluated trial quality and extracted data. We synthesised effect estimates using risk ratios (RR), risk differences (RD), and standardised mean differences (SMD). Our primary outcomes of interest were all‐cause mortality and neurodevelopmental disability. We used the GRADE approach to assess the certainty of evidence.

**Main results** We included five trials with a total of 482 preterm infants; there was one ongoing trial. The five included trials were generally small, but of good methodological quality. Enteral zinc supplementation compared to no zinc supplementationEnteral zinc supplementation started in hospitalised preterm infants may decrease all‐cause mortality (between start of intervention and end of follow‐up period) (RR 0.55, 95% CI 0.31 to 0.97; 3 studies, 345 infants; low‐certainty evidence). No data were available on long‐term neurodevelopmental outcomes at 18 to 24 months of (post‐term) age. Enteral zinc supplementation may have little or no effect on common morbidities such as bronchopulmonary dysplasia (RR 0.66, 95% CI 0.31 to 1.40, 1 study, 193 infants; low‐certainty evidence), retinopathy of prematurity (RR 0.14, 95% CI 0.01 to 2.70, 1 study, 193 infants; low‐certainty evidence), bacterial sepsis (RR 1.11, 95% CI 0.60 to 2.04, 2 studies, 293 infants; moderate‐certainty evidence), or necrotising enterocolitis (RR 0.08, 95% CI 0.00 to 1.33, 1 study, 193 infants; low‐certainty evidence).The intervention probably improves weight gain (SMD 0.46, 95% CI 0.28 to 0.64; 5 studies, 481 infants; moderate‐certainty evidence); and may slightly improve linear growth (SMD 0.75, 95% CI 0.36 to 1.14, 3 studies, 289 infants; low‐certainty evidence), but may have little or no effect on head growth (SMD 0.21, 95% CI ‐0.02 to 0.44, 3 studies, 289 infants; moderate‐certainty evidence).

**Authors&#039; conclusions** Enteral supplementation of zinc in preterm infants compared to no supplementation or placebo may moderately decrease mortality and probably improve short‐term weight gain and linear growth, but may have little or no effect on common morbidities of prematurity. There are no data to assess the effect of zinc supplementation on long‐term neurodevelopment.
AU  - Staub,
AU  - E.
AU  - Evers,
AU  - K.
AU  - Askie,
AU  - L.M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD012797.pub2
L1  - internal-pdf://0455609266/Staub_et_al-2021-Cochrane_Database_of_Systemat.pdf
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - Enteral zinc supplementation for prevention of morbidity and mortality in preterm neonates
ER  -
TY  - JOUR
AB  - **Importance:**
 Bullying is a prevalent and modifiable risk factor for mental health disorders. Although previous studies have supported the effectiveness of anti-bullying programs; their population impact and the association of specific moderators with outcomes are still unclear.

**Objective:**
To assess the effectiveness of school anti-bullying interventions, their population impact, and the association between moderator variables and outcomes.

**Data Sources:**
A search of Ovid MEDLINE, ERIC, and PsycInfo databases was conducted using 3 sets of search terms to identify randomized clinical trials (RCTs) assessing anti-bullying interventions published from database inception through February 2020. A manual search of reference lists of articles included in previous systematic reviews and meta-analyses was also performed.

**Study Selection:**
The initial literature search yielded 34 798 studies. Included in the study were articles that (1) assessed bullying at school; (2) assessed the effectiveness of an anti-bullying program; (3) had an RCT design; (4) reported results; and (5) were published in English. Of 16 707 studies identified, 371 met the criteria for review of full-text articles; 77 RCTs were identified that reported data allowing calculation of effect sizes (ESs). Of these, 69 independent trials were included in the final meta-analysis database.

**Data Extraction and Synthesis:** 
Random-effects and meta-regression models were used to derive Cohen d values with pooled 95% CIs as estimates of ES and to test associations between moderator variables and ES estimates. Population impact number (PIN), defined as the number of children in the total population for whom 1 event may be prevented by an intervention, was used as an estimate of the population impact of universal interventions targeting all students, regardless of individual risk.

**Main Outcomes and Measures:** 
The main outcomes are the effectiveness (measured by ES) and the population impact (measured by the PIN) of anti-bullying interventions on the following 8 variable categories: overall bullying, bullying perpetration, bullying exposure, cyberbullying, attitudes that discourage bullying, attitudes that encourage bullying, mental health problems (eg, anxiety and depression), and school climate as well as the assessment of potential assocations between trial or intervention characteristics and outcomes.

**Results:** 
This study included 77 samples from 69 RCTs (111659 participants [56511 in the intervention group and 55148 in the control group]). The weighted mean (range) age of participants in the intervention group was 11.1 (4-17) years and 10.8 (4-17) years in the control group. The weighted mean (range) proportion of female participants in the intervention group was 49.9% (0%-100%) and 50.5% (0%-100%) in the control group. Anti-bullying interventions were efficacious in reducing bullying (ES, -0.150; 95% CI, -0.191 to -0.109) and improving mental health problems (ES, -0.205; 95% CI, -0.277 to -0.133) at study end point, with PINs for universal interventions that target the total student population of 147 (95% CI, 113-213) and 107 (95% CI, 73-173), respectively. Duration of intervention was not statistically significantly associated with intervention effectiveness (mean [range] duration of interventions, 29.4 [1 to 144] weeks). The effectiveness of anti-bullying programs did not diminish over time during follow-up (mean [range] follow-up, 30.9 [2-104] weeks).

**Conclusions and Relevance:** 
Despite the small ESs and some regional differences in effectiveness, the population impact of school anti-bullying interventions appeared to be substantial. Better designed trials that assess optimal intervention timing and duration are warranted.
AD  - Fraguas, David. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), School of Medicine, Universidad Complutense, Madrid, Spain.Fraguas, David. Centro de Investigacion Biomedica en Red de Salud Mental (CIBERSAM), Madrid, Spain.Fraguas, David. Institute of Psychiatry and Mental Health, Hospital Clinico San Carlos, Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos (IdISSC), Madrid, Spain.Diaz-Caneja, Covadonga M. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), School of Medicine, Universidad Complutense, Madrid, Spain.Diaz-Caneja, Covadonga M. Centro de Investigacion Biomedica en Red de Salud Mental (CIBERSAM), Madrid, Spain.Ayora, Miriam. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), School of Medicine, Universidad Complutense, Madrid, Spain.Ayora, Miriam. Centro de Investigacion Biomedica en Red de Salud Mental (CIBERSAM), Madrid, Spain.Duran-Cutilla, Manuel. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), School of Medicine, Universidad Complutense, Madrid, Spain.Abregu-Crespo, Renzo. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), School of Medicine, Universidad Complutense, Madrid, Spain.Ezquiaga-Bravo, Iciar. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), School of Medicine, Universidad Complutense, Madrid, Spain.Ezquiaga-Bravo, Iciar. Department of Psychiatry, Hospital del Mar, Institut de Neuropsiquiatria i Addiccions, Barcelona, Catalonia, Spain.Martin-Babarro, Javier. Department of Developmental Psychology and Education, Universidad Complutense, Madrid, Spain.Arango, Celso. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), School of Medicine, Universidad Complutense, Madrid, Spain.Arango, Celso. Centro de Investigacion Biomedica en Red de Salud Mental (CIBERSAM), Madrid, Spain.
AN  - 33136156
AU  - Fraguas,
AU  - D.
AU  - Diaz-Caneja,
AU  - C.
AU  - M.
AU  - Ayora,
AU  - M.
AU  - Duran-Cutilla,
AU  - M.
AU  - Abregu-Crespo,
AU  - R.
AU  - Ezquiaga-Bravo,
AU  - I.
AU  - Martin-Babarro,
AU  - J.
AU  - Arango,
AU  - C.
DA  - Jan 01
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1001/jamapediatrics.2020.3541
DP  - Ovid Technologies
J2  - Jama, Pediatr
L1  - internal-pdf://1064867928/Fraguas-2021-Assessment of School Anti-Bullyin.pdf
LA  - English
N1  - Fraguas, DavidDiaz-Caneja, Covadonga MAyora, MiriamDuran-Cutilla, ManuelAbregu-Crespo, RenzoEzquiaga-Bravo, IciarMartin-Babarro, JavierArango, Celso
PY  - 2021
SP  - 44-55
T2  - JAMA Pediatrics
TI  - Assessment of School Anti-Bullying Interventions: A Meta-analysis of Randomized Clinical Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33136156
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33136156&amp;id=doi:10.1001%2Fjamapediatrics.2020.3541&amp;issn=2168-6203&amp;isbn=&amp;volume=175&amp;issue=1&amp;spage=44&amp;pages=44-55&amp;date=2021&amp;title=JAMA+Pediatrics&amp;atitle=Assessment+of+School+Anti-Bullying+Interventions%3A+A+Meta-analysis+of+Randomized+Clinical+Trials.&amp;aulast=Fraguas&amp;pid=%3Cauthor%3EFraguas+D%3C%2Fauthor%3E%3CAN%3E33136156%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://jamanetwork.com/journals/jamapediatrics/articlepdf/2772453/jamapediatrics_fraguas_2020_oi_200062_1609284055.45822.pdf
VL  - 175
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Evidence for the application of transcranial direct current stimulation (tDCS) in the clinical care of attention-deficit/hyperactivity disorder (ADHD) is limited. Therefore, we aimed to summarize study results using meta-analyses of measures of the cardinal symptoms of ADHD. 

**METHODS**: We conducted a systematic literature search (PubMed/pubpsych/PsychInfo/WOS) until 01/05/2020 for randomized controlled trials (RCTs) evaluating tDCS vs. control condition in patients with ADHD. A random effects meta-analysis of symptom-related outcomes was performed separately for data on the immediate effect and follow-up. Subgroup- and metaregression analyses for patient characteristics and tDCS parameters were included. 

**RESULTS**: Meta-analyzing 13 studies (n=308, age=23.7+/-13.3), including 20 study arms, tDCS had an immediate effect on overall symptom severity, inattention, and impulsivity, but not on hyperactivity. Results were significant in children and adolescents (8 studies, n=133, age=12.4+/-3.0). Follow-up data (3 days-4 weeks after stimulation) suggested an ongoing beneficial effect regarding overall symptom severity and a delayed effect on hyperactivity. 

**DISCUSSION**: TDCS seems to be a promising method to treat clinical symptoms in ADHD with long-lasting effects. Still, more research considering the individual neuropsychological and anatomical dispositions of the subjects is needed to optimize tDCS protocols and efficacy. Safety issues of tDCS treatment in children and adolescents are addressed.
AN  - 34167666
AU  - Brauer,
AU  - H.
AU  - Breitling-Ziegler,
AU  - C.
AU  - Moliadze,
AU  - V.
AU  - Galling,
AU  - B.
AU  - Prehn-Kristensen,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/bs.pbr.2021.01.013
L1  - internal-pdf://2210814525/Brauer-2021-Transcranial direct current stimul.pdf
PY  - 2021
SP  - 91-116
T2  - Progress in Brain Research
TI  - Transcranial direct current stimulation in attention-deficit/hyperactivity disorder: A meta-analysis of clinical efficacy outcomes
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34167666
VL  - 264
ER  -
TY  - JOUR
AB  - Depression and anxiety are the most common mental illnesses in adolescents. Rural schools are well-positioned to narrow the access gap confronting rural adolescents experiencing depression and anxiety; however, there is a paucity of research on the treatment of depression and anxiety in rural high schools. This critical review summarized the state of the field on rural school-based interventions to reduce adolescent depression and anxiety. Literature searches were conducted using PubMed, PsychINFO, EMBASE, ERIC, and CINAHL databases. Inclusion criteria identified peer-reviewed articles evaluating rural high-school based interventions for the treatment of depression and/or anxiety. Of the 322 articles screened, 82 articles were reviewed, with four articles satisfying inclusion criteria. All studies examined a group- or classroom-based program to reduce depression. Three studies reported either significant pre- to post-intervention improvements or clinical change in depressive symptoms or coping skills; one study found null effects. While promising, there is an on-going need for additional rigorous investigations on rural high-school based interventions for the treatment of depression and anxiety among teens. (PsycInfo Database Record (c) 2021 APA, all rights reserved) Impact Statement Public Significance Statement -This critical review of the literature reveals promising school-based treatments to reduce depression among rural adolescents. At the same time, there is a significant need for more research on school-based interventions for rural youth, especially as it pertains to anxiety disorders. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Berryhill, Blake: bberryhill@ches.ua.eduBerryhill, Blake: Human Development and Family Studies, The University of Alabama, Box 870160, Tuscaloosa, AL, US, 35401, bberryhill@ches.ua.eduBerryhill, Blake: Human Development and Family Studies, The University of Alabama, Tuscaloosa, AL, USCarlson, Catherine: School of Social Work, The University of Alabama, Tuscaloosa, AL, USHopson, Laura: School of Social Work, The University of Alabama, Tuscaloosa, AL, USCulmer, Nathan: College of Community Health Sciences, The University of Alabama, Tuscaloosa, AL, USWilliams, Nelle: College of Community Health Sciences, The University of Alabama, Tuscaloosa, AL, US
AN  - 2021-45502-001
AU  - Berryhill,
AU  - B.
AU  - Carlson,
AU  - C.
AU  - Hopson,
AU  - L.
AU  - Culmer,
AU  - N.
AU  - Williams,
AU  - N.
DA  - May
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/rmh0000183
DP  - Ovid Technologies
KW  - adolescence, anxiety, depression, school, mental health
KW  - *Anxiety Disorders
KW  - *Major Depression
KW  - *Mental Health
KW  - *Rural Environments
KW  - *School Based Intervention
KW  - Adolescent Psychopathology
KW  - Anxiety
KW  - Mental Health Services
KW  - Treatment
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Educational Psychology [3500]
KW  - Human Adolescence (13-17 yrs)
L1  - internal-pdf://4107951208/Berryhill-2021.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2021
SP  - No Pagination Specified
T2  - Journal of Rural Mental Health
TI  - Adolescent depression and anxiety treatment in rural schools: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-45502-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2Frmh0000183&amp;issn=1935-942X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=No&amp;pages=No+Pagination+Specified&amp;date=2021&amp;title=Journal+of+Rural+Mental+Health&amp;atitle=Adolescent+depression+and+anxiety+treatment+in+rural+schools%3A+A+systematic+review.&amp;aulast=Berryhill&amp;pid=%3Cauthor%3EBerryhill%2C+Blake%3C%2Fauthor%3E%3CAN%3E2021-45502-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - There is a lack of services to support adolescents and adults with ASD in different areas including social-communication intervention. The purpose of this study is to conduct a meta-analysis determining effects of social-communication interventions in improving social-communication skills for adolescents and adults with ASD. A search of databases yielded 2,353 potential documents of which 41 documents met inclusion criteria. The finding of this study indicated that social-communication interventions across all documents are moderately effective in improving social-communication skills for adolescents and adults with ASD. This study investigated the effectiveness of social-communication interventions for these populations and also examined differential effects based on the moderator categories. There are statistically significant differences found for some potential moderators (interventions, implementers, communicative functions, and type of setting). Additional details on implementation, limitations, and future research are discussed.
AN  - WOS:000745815300001
AU  - Wattanawongwan,
AU  - S.
AU  - Ganz,
AU  - J.
AU  - B.
AU  - Hong,
AU  - E.
AU  - R.
AU  - Dunn,
AU  - C.
AU  - Yllades,
AU  - V.
AU  - Pierson,
AU  - L.
AU  - M.
AU  - Baek,
AU  - E.
AU  - Foster,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40489-021-00300-8
L1  - internal-pdf://2773159403/Interventions for Improving Social-Communicati.pdf
PY  - 2021
SP  - 15
T2  - Review Journal of Autism and Developmental Disorders
TI  - Interventions for Improving Social-Communication Skills for Adolescents and Adults with ASD: a Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000745815300001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-021-00300-8.pdf
ER  -
TY  - JOUR
AB  - **Background** Parents are the primary caregivers of young children. Responsive parent-child relationships and parental support for learning during the earliest years of life are crucial for promoting early child development (ECD). 

We conducted a global systematic review and meta-analysis to evaluate the effectiveness of parenting interventions on ECD and parenting outcomes. Methods and findings We searched MEDLINE, Embase, PsycINFO, CINAHL, Web of Science, and Global Health Library for peer-reviewed, published articles from database inception until November 15, 2020. We included randomized controlled trials (RCTs) of parenting interventions delivered during the first 3 years of life that evaluated at least 1 ECD outcome. At least 2 reviewers independently screened, extracted data, and assessed study quality from eligible studies. ECD outcomes included cognitive, language, motor, and socioemotional development, behavior problems, and attachment. Parenting outcomes included parenting knowledge, parenting practices, parent-child interactions, and parental depressive symptoms. We calculated intervention effect sizes as the standardized mean difference (SMD) and estimated pooled effect sizes for each outcome separately using robust variance estimation meta-analytic approaches. We used random-effects meta-regression models to assess potential effect modification by country-income level, child age, intervention content, duration, delivery, setting, and study quality. This review was registered with PROSPERO (CRD42018092458 and CRD42018092461). 

Of the 11,920 articles identified, we included 111 articles representing 102 unique RCTs. Pooled effect sizes indicated positive benefits of parenting interventions on child cognitive development (SMD = 0.32, 95% CI [confidence interval]: 0.23, 0.40, P &lt; 0.001), language development (SMD = 0.28, 95% CI: 0.18 to 0.37, P &lt; 0.001), motor development (SMD = 0.24, 95% CI: 0.15 to 0.32, P &lt; 0.001), socioemotional development (SMD = 0.19, 95% CI: 0.10 to 0.28, P &lt; 0.001), and attachment (SMD = 0.29, 95% CI: 0.18 to 0.40, P &lt; 0.001) and reductions in behavior problems (SMD = -0.13, 95% CI: -0.18 to -0.08, P &lt; 0.001). Positive benefits were also found on parenting knowledge (SMD = 0.56, 95% CI: 0.33 to 0.79, P &lt; 0.001), parenting practices (SMD = 0.33, 95% CI: 0.22 to 0.44, P &lt; 0.001), and parent-child interactions (SMD = 0.39, 95% CI: 0.24 to 0.53, P &lt; 0.001). However, there was no significant reduction in parental depressive symptoms (SMD = -0.07, 95% CI: -0.16 to 0.02, P = 0.08). Subgroup analyses revealed significantly greater effects on child cognitive, language, and motor development, and parenting practices in low- and middle-income countries compared to high-income countries; and significantly greater effects on child cognitive development, parenting knowledge, parenting practices, and parent-child interactions for programs that focused on responsive caregiving compared to those that did not. On the other hand, there was no clear evidence of effect modification by child age, intervention duration, delivery, setting, or study risk of bias. Study limitations include considerable unexplained heterogeneity, inadequate reporting of intervention content and implementation, and varying quality of evidence in terms of the conduct of trials and robustness of outcome measures used across studies. 
Copyright: &copy; 2021 Jeong et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AD  - (Jeong, Franchett, Ramos de Oliveira, Rehmani, Yousafzai) Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, United StatesJ. Jeong, Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, United States. E-mail: joshua.jeong@hsph.harvard.edu
AN  - 2012088154
AU  - Jeong,
AU  - J.
AU  - Franchett,
AU  - E.
AU  - E.
AU  - Ramos
AU  - de
AU  - Oliveira,
AU  - C.
AU  - V.
AU  - Rehmani,
AU  - K.
AU  - Yousafzai,
AU  - A.
AU  - K.
DA  - May
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pmed.1003602
DP  - Ovid Technologies
KW  - care behavior
KW  - child
KW  - child development
KW  - child parent relation
KW  - Cinahl
KW  - cognitive development
KW  - comparative effectiveness
KW  - controlled study
KW  - depression
KW  - effect size
KW  - Embase
KW  - female
KW  - global health
KW  - high income country
KW  - human
KW  - language development
KW  - male
KW  - Medline
KW  - meta analysis
KW  - middle income country
KW  - motor development
KW  - problem behavior
KW  - PsycINFO
KW  - randomized controlled trial (topic)
KW  - review
KW  - systematic review
KW  - Web of Science
L1  - internal-pdf://3359537088/Jeong-2021.pdf
LA  - English
M3  - Review
PY  - 2021
T2  - PLoS Medicine
TI  - Parenting interventions to promote early child development in the first three years of life: A global systematic review and meta-analysis
UR  - https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1003602&amp;type=printable
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2012088154
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33970913&amp;id=doi:10.1371%2Fjournal.pmed.1003602&amp;issn=1549-1277&amp;isbn=&amp;volume=18&amp;issue=5&amp;spage=e1003602&amp;pages=&amp;date=2021&amp;title=PLoS+Medicine&amp;atitle=Parenting+interventions+to+promote+early+child+development+in+the+first+three+years+of+life%3A+A+global+systematic+review+and+meta-analysis&amp;aulast=Jeong&amp;pid=%3Cauthor%3EJeong+J.%3C%2Fauthor%3E%3CAN%3E2012088154%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pmed.1003602/1/pmed.1003602.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&amp;X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210618%2Fauto%2Fstorage%2Fgoog4_request&amp;X-Goog-Date=20210618T081241Z&amp;X-Goog-Expires=86400&amp;X-Goog-SignedHeaders=host&amp;X-Goog-Signature=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
VL  - 18 (5) (no pagination)
ER  -
TY  - JOUR
AB  - Attention deficit hyperactivity disorder (ADHD) is one of the most frequent childhood psychiatric problems. 

**Objective:** 
The objective of this study was to identify, synthesize the results, and critically evaluate all Cochrane systematic reviews (SRs) on the pharmacological interventions for children and adolescents (up to age 18) diagnosed with ADHD. 

**Methods:** 
The search was performed in the Cochrane Database of Systematic Reviews (via Wiley) in July 2020. 

**Results:** 
The search strategy resulted in four SRs of high methodological quality, analyzing 51 randomized clinical trials (9,013 participants). Compared to placebo, treatment with tricyclic antidepressants (TCAs) (desipramine), amphetamine, and methylphenidate showed improvement in symptoms such as difficulty concentrating, impulsivity, and hyperactivity in the short term (up to 6 months). There was an increase in the occurrence of adverse events, such as reduced appetite, difficulty sleeping, and abdominal pain. Insufficient evidence was found to support the effects of supplementation with polyunsaturated fatty acids. 

**Conclusions:** 
The use of TCAs, amphetamine, and methylphenidate in children and adolescents with ADHD seems to present positive effects and higher rates of minor adverse events when compared to placebo.
AN  - 35509804
AU  - Santos,
AU  - G.
AU  - M.
AU  - Santos,
AU  - E.
AU  - M.
AU  - Mendes,
AU  - G.
AU  - D.
AU  - Fragoso,
AU  - Y.
AU  - D.
AU  - Souza,
AU  - M.
AU  - R.
AU  - Martimbianco,
AU  - A.
AU  - L.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1590/1980-57642021dn15-040001
L1  - internal-pdf://1442197900/A review of Cochrane reviews on pharmacol-2021.pdf
PY  - 2021
SP  - 421-427
T2  - Dementia &amp; Neuropsychologia
TI  - A review of Cochrane reviews on pharmacological treatment for attention deficit hyperactivity disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35509804
UR  - https://www.scielo.br/j/dn/a/dhgFPzSVLm4jnFP6pHg87KD/?lang=en&amp;format=pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Many children with autism spectrum disorder (ASD) are at-risk for academic difficulties, particularly reading comprehension. The implementation of research-supported reading comprehension interventions for this population is critical for optimal academic success. 

The current meta-analysis of single-case design (SCD) studies evaluates the effectiveness of reading comprehension interventions for children with ASD through design comparable effect size (BC-SMD) analyses, log response ratio for increase (LRR-i), and multilevel modeling (MLM). We included SCD studies (20 studies, 60 participants) published in English that met What Works Clearinghouse (WWC) criteria with at least reservations with at least one participant (less than 18 years of age) who had ASD with reading comprehension defined as the dependent variable. 

Research on this topic is still emerging, but our preliminary results suggest that reading comprehension interventions show promise for children with ASD (BC-SMDoverall = 2.97, 95% CI = 1.85-3.97, p &lt; .001). Further analyses indicate that intervention effectiveness, although broadly effective, differs across child race/ethnicity, chi2(4) = 40.4, p &lt; .001; age, chi2(2) = 52.0, p &lt; .001; participant disability (ASD vs. ASD + speech language impairment), chi2(2) = 44.3, p &lt; .001; and study method quality (meeting WWC vs. meeting WWC with reservations), chi2(2) = 150.4, p &lt; .001. (PsycInfo Database Record (c) 2021 APA, all rights reserved) Impact Statement Impact and Implications -This meta-analysis found that reading comprehension interventions are broadly effective for children with autism spectrum disorder (ASD). However, intervention effectiveness differed across child race/ethnicity, age, and the presence of a co-occurring speech-language impairment. 

These results are important for school contexts given that children with ASD are at-risk for reading difficulties, which may negatively impact overall achievement. Implications and recommendations for school-based professionals regarding reading comprehension intervention implementation for children with ASD are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - McClain, Maryellen Brunson: maryellen.mcclainverdoes@usu.eduMcClain, Maryellen Brunson: Department of Psychology, Utah State University, Logan, UT, US, maryellen.mcclainverdoes@usu.eduMcClain, Maryellen Brunson: Department of Psychology, Utah State University, Logan, UT, USHaverkamp, Cassity R.: Department of Psychology, Utah State University, Logan, UT, USBenallie, Kandice J.: Department of Psychology, Utah State University, Logan, UT, USSchwartz, Sarah E.: Department of Psychology, Utah State University, Logan, UT, USSimonsmeier, Vicki: Department of Communicative Disorders and Deaf Education, Utah State University, Logan, UT, US
AN  - 2021-38272-004
AU  - McClain,
AU  - M.
AU  - B.
AU  - Haverkamp,
AU  - C.
AU  - R.
AU  - Benallie,
AU  - K.
AU  - J.
AU  - Schwartz,
AU  - S.
AU  - E.
AU  - Simonsmeier,
AU  - V.
DA  - Mar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/spq0000424
DP  - Ovid Technologies
KW  - achievement, meta-analysis, autism spectrum disorder, reading comprehension interventions, single-case design
KW  - *Autism Spectrum Disorders
KW  - *Dependent Variables
KW  - *Intervention
KW  - *Reading Comprehension
KW  - *Simulation
KW  - Meta Analysis
KW  - Developmental Disorders &amp; Autism [3250]
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://0307829146/McClain-2021.pdf
LA  - English
M3  - Meta Analysis
PY  - 2021
SP  - 107-121
T2  - School Psychology
TI  - How effective are reading comprehension interventions for children with ASD? A meta-analysis of single-case design studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-38272-004
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2Fspq0000424&amp;issn=2578-4218&amp;isbn=&amp;volume=36&amp;issue=2&amp;spage=107&amp;pages=107-121&amp;date=2021&amp;title=School+Psychology&amp;atitle=How+effective+are+reading+comprehension+interventions+for+children+with+ASD%3F+A+meta-analysis+of+single-case+design+studies.&amp;aulast=McClain&amp;pid=%3Cauthor%3EMcClain%2C+Maryellen+Brunson%3C%2Fauthor%3E%3CAN%3E2021-38272-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 36
ER  -
TY  - JOUR
AB  - Technology-assisted parent-mediated interventions improve accessibility and are acceptable but not proven to be effective. We conducted a systematic search of 6 databases. We included and analysed results from studies on social and communication outcomes. Sixteen Randomised-Controlled-Trials (RCTs) with 748 participants were included. Most studies were rated as of good quality. Meta-analysis suggested that interventions were probably effective in improving emotion recognition. No significant differences were found in social communication, social functioning or language outcomes. At present, isolated tech interventions do not fulfil criteria for promising or established evidence-based interventions for ASD. Future research needs to focus on improving the effectiveness of technology-assisted parent-mediated interventions for ASD. Prospero Registration Number: CRD42020162825.
AN  - WOS:000677945500004
AU  - Pi,
AU  - H.
AU  - J.
AU  - Kallapiran,
AU  - K.
AU  - Munivenkatappa,
AU  - S.
AU  - Kandasamy,
AU  - P.
AU  - Kirubakaran,
AU  - R.
AU  - Russell,
AU  - P.
AU  - Eapen,
AU  - V.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s10803-021-05206-2
L1  - internal-pdf://2129579213/Pi-Meta-Analysis of RCTs of Technology-Assiste.pdf
PY  - 2021
SP  - 19
T2  - Journal of Autism and Developmental Disorders
TI  - Meta-Analysis of RCTs of Technology-Assisted Parent-Mediated Interventions for Children with ASD
UR  - &lt;Go to ISI&gt;://WOS:000677945500004
UR  - https://link.springer.com/content/pdf/10.1007/s10803-021-05206-2.pdf
ER  -
TY  - JOUR
AB  - **Background**: Children&#039;s social care/child welfare services, are under pressure to maximize the value of resource expenditure in meeting the needs of children and young people exposed to risk factors for care entry or residing in care. Economic evaluations can support the decision to adopt, routinize or discontinue an intervention, informing the allocation of limited resources. There is a paucity of economic evaluations in children&#039;s social care, partly because this is an emerging area, hence topic-specific methods are lacking. Prior to the development and recommendation of methods, it is important to systematically synthesize those adopted to highlight challenges that have arisen and guide future research. 

**Objective**: To assess the methods applied and the cost-effectiveness evidence generated by economic evaluations of children&#039;s social care interventions. 

**Methods**: Searches of electronic databases and websites were carried out to identify full economic evaluations of children&#039;s social care interventions in journal articles and the grey literature. A narrative synthesis of methods adopted and cost-effectiveness results is presented. 

**Results**: Twenty studies were eligible for inclusion. These covered parenting programs (n = 8), in addition to a diverse range of other interventions. Cost-effectiveness analysis was the most common approach taken (n = 17) and a large number of studies concluded that the intervention was cost-effective (n = 14). 

**Conclusion**: The number of published economic evaluations of children&#039;s social care interventions is limited. The available evidence supports the adoption of several of the interventions evaluated, however, the review highlighted a number of challenges in the use of standard economic evaluations methods in this area. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - El-Banna, Asmaa: Asmaa.El-Banna@warwick.ac.ukEl-Banna, Asmaa: Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, United Kingdom, CV4 7AL, Asmaa.El-Banna@warwick.ac.ukEl-Banna, Asmaa: Warwick Clinical Trials Unit, University of Warwick, Coventry, United KingdomPetrou, Stavros: Warwick Clinical Trials Unit, University of Warwick, Coventry, United KingdomYiu, Hei Hang Edmund: Warwick Clinical Trials Unit, University of Warwick, Coventry, United KingdomDaher, Shahd: Nuffield Department of Primary Care Health Sciences, Medical Sciences Division, University of Oxford, Oxford, United KingdomForrester, Donald: CASCADE: Children&#039;s Social Care Research and Development Centre, School of Social Sciences, Cardiff University, Cardiff, United KingdomScourfield, Jonathan: CASCADE: Children&#039;s Social Care Research and Development Centre, School of Social Sciences, Cardiff University, Cardiff, United KingdomWilkins, David: CASCADE: Children&#039;s Social Care Research and Development Centre, School of Social Sciences, Cardiff University, Cardiff, United KingdomEvans, Rhiannon: Centre for Development, Evaluation, Complexity and Implementation in Public Health Improvement (DECIPHer), School of Social Sciences, Cardiff University, Cardiff, United KingdomTurley, Ruth: Centre for Development, Evaluation, Complexity and Implementation in Public Health Improvement (DECIPHer), School of Social Sciences, Cardiff University, Cardiff, United KingdomWallace, Sarah: Faculty of Life Sciences and Education, University of South Wales, Wales
AN  - 2021-16680-001
AU  - El-Banna,
AU  - A.
AU  - Petrou,
AU  - S.
AU  - Yiu,
AU  - H.
AU  - H.
AU  - E.
AU  - Daher,
AU  - S.
AU  - Forrester,
AU  - D.
AU  - Scourfield,
AU  - J.
AU  - Wilkins,
AU  - D.
AU  - Evans,
AU  - R.
AU  - Turley,
AU  - R.
AU  - Wallace,
AU  - S.
DA  - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.childyouth.2020.105864
DP  - Ovid Technologies
KW  - Economic evaluation, Cost-effectiveness analysis, Child welfare, Systematic review
KW  - *Child Care
KW  - *Child Welfare
KW  - *Economics
KW  - *Intervention
KW  - *Social Services
KW  - Parenting
KW  - Community &amp; Social Services [3373]
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://3870503303/El-Banna-2021.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2021
T2  - Children and Youth Services Review Vol 121 2021, ArtID 105864
TI  - Systematic review of economic evaluations of children&#039;s social care interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-16680-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2020.105864&amp;issn=0190-7409&amp;isbn=&amp;volume=121&amp;issue=&amp;spage=105864&amp;pages=&amp;date=2021&amp;title=Children+and+Youth+Services+Review&amp;atitle=Systematic+review+of+economic+evaluations+of+children%27s+social+care+interventions.&amp;aulast=El-Banna&amp;pid=%3Cauthor%3EEl-Banna%2C+Asmaa%3C%2Fauthor%3E%3CAN%3E2021-16680-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 121
ER  -
TY  - JOUR
AB  - This meta-analysis assessed the efficacy of the Cogmed Working Memory Training program in improving near-transfer measures (verbal and visuospatial working memory) and far-transfer measures (attention, executive function, and academic achievement) in school-age children with and without neurological insults or disorders. Relevant studies were searched in databases and clinical trial registries using the keyword Cogmed. Ten published studies and unpublished data from one study met the inclusion criteria. Hedges g was calculated for each outcome measure obtained at pre-intervention, post-intervention, and 3-6 month time points. Analysis compared outcome measures in the control versus experimental groups and examined the role of moderators on treatment effects (control group intervention, intervention environment). Data revealed significant medium-size effects of the Cogmed program in improving verbal and visuospatial working memory post-intervention and for verbal working memory only at the 3-6 month time point. However, the training did not generalize to the far-transfer measures. Analyses indicated that only the type of intervention provided for the control group moderated treatment effects on verbal and visual working memory. Meta-analytic findings suggest that the Cogmed program leads to short-term improvements and in some cases, long-term improvements in working memory in school-age children; however, these effects may not generalize to far-transfer measures.
AN  - WOS:000657957400001
AU  - Bharadwaj,
AU  - S.
AU  - V.
AU  - Yeatts,
AU  - P.
AU  - Headley,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/21622965.2021.1920943
L1  - internal-pdf://1235375279/Bharadwaj-Efficacy of cogmed working memory tr.pdf
PY  - 2021
SP  - 13
T2  - Applied Neuropsychology-Child
TI  - Efficacy of cogmed working memory training program in improving working memory in school-age children with and without neurological insults or disorders: A meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000657957400001
UR  - https://www.tandfonline.com/doi/full/10.1080/21622965.2021.1920943
UR  - https://www.tandfonline.com/doi/pdf/10.1080/21622965.2021.1920943?needAccess=true
ER  -
TY  - JOUR
AB  - Growing up in migrant families is a well-known distal risk factor related to poorer outcomes in child and adolescent health, academic, socioemotional and behavioural development. This article reviews the effects of various prevention measures such as early education programmes, cognitive and language training or parent and teacher training on child and adolescent developmental outcomes in immigration samples. Using several comprehensive literature searches, we found 138 research reports with 141 studies and 175 comparisons on preventing negative effects of immigration. Overall, programmes yielded an effect size of d = 0.26 at post-test using the random effect model. These effects decreased over time while still differing significantly from zero. A cross-tabulation of prevention approach/programme type by different outcome domains revealed several important results such as high effects of child cognitive and language training programmes on child academic and language outcomes and relatively low effects of all programmes on child socioemotional outcomes. In addition, individualised and culturally tailored programmes seems to be more effective. However, generalised effects on more distal educational outcomes (e.g., school degrees) were generally weak. Hence, it remains questionable whether individual psychosocial and educational programmes are able to counterbalance the multifaceted risks of immigration.
AN  - WOS:000592275000001
AU  - Beelmann,
AU  - A.
AU  - Arnold,
AU  - L.
AU  - S.
AU  - Schulz,
AU  - S.
DA  - JUN
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/ijop.12725
L1  - internal-pdf://2966362874/Beelmann-2021.pdf
PY  - 2021
SP  - 478-490
T2  - INTERNATIONAL JOURNAL OF PSYCHOLOGY
TI  - Buffering negative effects of immigration on cognitive, social, and educational development: A multinational meta-analysis of child and adolescent prevention programmes
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijop.12725?download=true
VL  - 56
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Universal prevention approaches that target the general population can be effective for promoting children&#039;s health. This overview aims to summarize evidence presented in existing reviews of school-based interventions.

**METHODS**: We present an overview of evidence sourced from Campbell and Cochrane systematic reviews. These reviews examined randomized controlled trials concerning school-based health-promotion programs for children (mostly aged 4-18 years) in the general population.

**RESULTS**: We identified 56 high-quality reviews. The reviews focused on emotional and behavioral outcomes, infectious diseases, injury reduction, mental health, nutrition intake, oral health, physical and developmental changes, sense-organ diseases, sexual-health outcomes, and substance use/abuse. Positive evidence-such as vision screening plus provision of free spectacles for spectacle wear increase and a combination of social competence and social-influence approaches for preventing illicit drug use-were considered high certainty.

**CONCLUSIONS**: Of the various interventions implemented in school settings that involved people from various occupations, some positive effects were found. In most cases, evidence certainty was negatively affected by a high risk of bias within studies, inconsistencies within the estimates, and insufficient sample sizes. Further primary studies in these areas would be helpful for accumulating evidence to promote stronger cooperation between health and education stakeholders.
AD  - Suto, Maiko. Department of Health Policy, National Center for Child Health and Development, 10-1, Okura 2 chome, Setagaya, Tokyo 157-8535, Japan.Miyazaki, Celine. Department of Health Policy, National Center for Child Health and Development, 10-1, Okura 2 chome, Setagaya, Tokyo 157-8535, Japan.Yanagawa, Yuko. Department of Health Policy, National Center for Child Health and Development, 10-1, Okura 2 chome, Setagaya, Tokyo 157-8535, Japan.Takehara, Kenji. Division of Health Policy Development and Research, (takehara-k@ncchd.go.jp), Department of Health Policy, National Center for Child Health and Development, 10-1, Okura 2 chome, Setagaya, Tokyo 157-8535, Japan.Kato, Tsuguhiko. Department of Social Medicine, National Center for Child Health and Development, 10-1, Okura 2 chome, Setagaya, Tokyo 157-8535, Japan.Gai, Ruoyan. Department of Empirical Social Security Research, National Institute of Population and Social Security Research, 2-2-3, Uchisaiwaicyo, Chiyoda-ku, Tokyo 100-0011, Japan.Ota, Erika. Global Health Nursing, Graduate school of nursing science, St. Luke&#039;s international University, 10-1, Akashicho, Chuo-ku, Tokyo 104-0044, Japan.Mori, Rintaro. Health Policy for Children and Families, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
AN  - 33818772
AU  - Suto,
AU  - M.
AU  - Miyazaki,
AU  - C.
AU  - Yanagawa,
AU  - Y.
AU  - Takehara,
AU  - K.
AU  - Kato,
AU  - T.
AU  - Gai,
AU  - R.
AU  - Ota,
AU  - E.
AU  - Mori,
AU  - R.
DA  - Apr 05
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/josh.13021
DP  - Ovid Technologies
J2  - J Sch Health
L1  - internal-pdf://1877951681/Suto-2021.pdf
LA  - English
N1  - Using Smart Source ParsingAprSuto, MaikoMiyazaki, CelineYanagawa, YukoTakehara, KenjiKato, TsuguhikoGai, RuoyanOta, ErikaMori, Rintaro
PY  - 2021
SP  - 05
T2  - Journal of School Health
TI  - Overview of Evidence Concerning School-Based Interventions for Improving the Health of School-Aged Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33818772
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33818772&amp;id=doi:10.1111%2Fjosh.13021&amp;issn=0022-4391&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+School+Health&amp;atitle=Overview+of+Evidence+Concerning+School-Based+Interventions+for+Improving+the+Health+of+School-Aged+Children+and+Adolescents.&amp;aulast=Suto&amp;pid=%3Cauthor%3ESuto+M%3C%2Fauthor%3E%3CAN%3E33818772%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/10.1111/josh.13021
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/josh.13021?download=true
VL  - 05
ER  -
TY  - JOUR
AB  - **BACKGROUND**: There is presently no certainty about the ideal feeding intervals for preterm infants. Shorter feeding intervals of, for example, two hours, have the theoretical advantage of allowing smaller volumes of milk. This may have the potential to reduce the incidence and severity of gastro-oesophageal reflux. Longer feeding intervals have the theoretical advantage of allowing more gastric emptying between two feeds. This potentially provides periods of rest (and thus less hyperaemia) for an immature digestive tract. OBJECTIVES: To determine the safety of shorter feeding intervals (two hours or shorter) versus longer feeding intervals (three hours or more) and to compare the effects in terms of days taken to regain birth weight and to achieve full feeding. SEARCH 

**METHODS**: We used the standard search strategy of Cochrane Neonatal to run comprehensive searches in CENTRAL (2020, Issue 6) and Ovid MEDLINE and Epub Ahead of Print, In-Process &amp; Other Non-Indexed Citations, Daily and Versions, and CINAHL on 25 June 2020. We searched clinical trials databases and the reference lists of retrieved articles for randomised controlled trials (RCTs) and quasi-RCTs. SELECTION CRITERIA: We included RCTs and quasi-RCTs comparing short (e.g. one or two hours) versus long (e.g. three or four hours) feeding intervals in preterm infants of any birth weight, all or most of whom were less than 32 weeks&#039; gestation. Infants could be of any postnatal age at trial entry, but eligible infants should not have received feeds before study entry, with the exception of minimal enteral feeding. We included studies of nasogastric or orogastric bolus feeding, breast milk or formula, in which the feeding interval is the intervention. DATA COLLECTION AND ANALYSIS: We used standard methodological procedures expected by Cochrane. We used the GRADE approach to assess the certainty of evidence. Our primary outcomes were days taken to achieve full enteral feeding and days to regain birth weight. Our other outcomes were duration of hospital stay, episodes of necrotising enterocolitis (NEC) and growth during hospital stay (weight, length and head circumference). 

**MAIN RESULTS**: We included four RCTs, involving 417 infants in the review. One study involving 350 infants is awaiting classification. All studies compared two-hourly versus three-hourly feeding interval. The risk of bias of the included studies was generally low, but all studies had high risk of performance bias due to lack of blinding of the intervention. Three studies were included in meta-analysis for the number of days taken to achieve full enteral feeding (351 participants). The mean days to achieve full feeds was between eight and 11 days. There was little or no difference in days taken to achieve full enteral feeding between two-hourly and three-hourly feeding, but this finding was of low certainty (mean difference (MD) ‒0.62, 95% confidence interval (CI) ‒1.60 to 0.36). There was low-certainty evidence that the days taken to regain birth weight may be slightly longer in infants receiving two-hourly feeding than in those receiving three-hourly feeding (MD 1.15, 95% CI 0.11 to 2.20; 3 studies, 350 participants). We are uncertain whether shorter feeding intervals have any effect on any of our secondary outcomes including the duration of hospital stay (MD ‒3.36, 95% CI ‒9.18 to 2.46; 2 studies, 207 participants; very low-certainty evidence) and the risk of NEC (typical risk ratio 1.07, 95% CI 0.54 to 2.11; 4 studies, 417 participants; low-certainty evidence). No study reported growth during hospital stay. 

**AUTHORS&#039; CONCLUSIONS**: The low-certainty evidence we found in this review suggests that there may be no clinically important differences between two- and three-hourly feeding intervals. There is insufficient information about potential feeding complications and in particular NEC. No studies have looked at the effect of other feeding intervals and there is no long-term data on neurodevelopment or growth.
AD  - Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Malaysia.Department of Paediatrics, Hospital USM, Kubang Kerian, Malaysia.Department of Paediatrics, RCSI &amp; UCD Malaysia Campus (formerly Penang Medical College), George Town, Malaysia.
AN  - 34415568
AU  - Ibrahim,
AU  - N.
AU  - R.
AU  - Van
AU  - Rostenberghe,
AU  - H.
AU  - Ho,
AU  - J.
AU  - J.
AU  - Nasir,
AU  - A.
DA  - Aug 19
DB  - My EndNote Library.enl
DO  - 10.1002/14651858.CD012322.pub2
DP  - NLM
J2  - The Cochrane database of systematic reviews
LA  - eng
N1  - 1469-493xIbrahim, Nor RosidahVan Rostenberghe, HansHo, Jacqueline JNasir, AriffinJournal ArticleResearch Support, Non-U.S. Gov&#039;tReviewCochrane Database Syst Rev. 2021 Aug 19;8(8):CD012322. doi: 10.1002/14651858.CD012322.pub2.
PY  - 2021
SP  - Cd012322
T2  - Cochrane Database Syst Rev
TI  - Short versus long feeding interval for bolus feedings in very preterm infants
VL  - 8
ER  -
TY  - JOUR
AB  - Intranasal oxytocin has been shown to promote social functioning and has recently been applied as a treatment for autism spectrum disorders (ASD). The current meta-analysis aims to assess the crucial question of oxytocin&#039;s efficacy in the treatment of ASD. 

We performed a systematic literature search, including randomized, single- or double-blind/open-label and placebo-controlled clinical trials as well as single-arm, non-randomized and uncontrolled studies investigating exogenous oxytocin effect on ASD. 

A total of 28 studies (N = 726 ASD patients) met our predefined inclusion criteria. We used a multilevel meta-analytic model and found that oxytocin had beneficial effects on social functioning, but did not find strong evidence for symptoms improvement in the non-social domain. 

Our findings suggest that oxytocin administration can be regarded as an effective treatment for some core aspects of ASD, especially in the domain of social functioning, highlighting the promise of using oxytocin as a new-generation therapeutic to address core social impairments in ASD. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Yu, Rongjun: rongjunyu@hkbu.edu.hkYu, Rongjun: Department of Management, School of Business, Hong Kong Baptist University, Hong Kong, China, rongjunyu@hkbu.edu.hkHuang, Yi: Department of Applied Psychology, Lingnan University, Hong Kong, ChinaHuang, Xin: School of Public Health, Peking University, Beijing, ChinaEbstein, Richard P.: C2BEF (China Center for Behavior Economics and Finance), Southwestern University of Finance and Economics (SWUFE), ChinaYu, Rongjun: Department of Management, School of Business, Hong Kong, China
AN  - 2021-18243-003
AU  - Huang,
AU  - Y.
AU  - Huang,
AU  - X.Ebstein,
AU  - R.
AU  - P.
AU  - Yu,
AU  - R.
DA  - Mar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.neubiorev.2020.12.028
DP  - Ovid Technologies
KW  - Oxytocin, Autism Spectrum Disorder, Social functioning, Non-social domain improvement
KW  - *Autism Spectrum Disorders
KW  - *Drug Administration Methods
KW  - *Oxytocin
KW  - *Social Functioning
KW  - Drug Therapy
KW  - Clinical Psychopharmacology [3340]
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older)
L1  - internal-pdf://1649613678/Huang-2021.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2021
SP  - 18-27
T2  - Neuroscience and Biobehavioral Reviews
TI  - Intranasal oxytocin in the treatment of autism spectrum disorders: A multilevel meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-18243-003
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.neubiorev.2020.12.028&amp;issn=0149-7634&amp;isbn=&amp;volume=122&amp;issue=&amp;spage=18&amp;pages=18-27&amp;date=2021&amp;title=Neuroscience+and+Biobehavioral+Reviews&amp;atitle=Intranasal+oxytocin+in+the+treatment+of+autism+spectrum+disorders%3A+A+multilevel+meta-analysis.&amp;aulast=Huang&amp;pid=%3Cauthor%3EHuang%2C+Yi%3C%2Fauthor%3E%3CAN%3E2021-18243-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 122
ER  -
TY  - JOUR
AB  - Several reviews have been conducted on children&#039;s outcomes following exposure to intimate partner violence (IPV), but there remain inconsistent findings. We conducted a meta-analysis on child emotional and behavioral outcomes of IPV exposure interventions, based on published reviews that included a child component. We also explored relative effect sizes by examining moderators of the effect sizes across studies. 

This meta-analysis included 21 evaluation studies across 12 published reviews, which were located using a multiple database systematic search of English publications between 2000 and 2019. Studies were required to evaluate IPV interventions that included children, to gather quantitative pre- and post-intervention data on child outcomes, to use standardized instruments, and to present data in a format that could be used in a meta-analysis. 

Results indicated an overall pre- to post-intervention medium effect size (d = 0.49), with effect sizes ranging from small to large depending on the specific outcome. Improvements at follow-up were maintained for internalizing behaviors but decreased for trauma-related symptoms and social, externalizing, and total behaviors. 

However, externalizing and total behavior outcomes still had significant effect sizes in the small-to-medium range (d = 0.36 and 0.44). There were greater intervention effects when treatment was not exclusively trauma-specific. It appears that IPV exposure interventions are generally effective for improving children&#039;s emotional and behavioral well-being, although interventions would benefit from greater tailoring to children&#039;s specific needs. Interventions may also benefit from incorporating various content areas (both trauma-specific and non-trauma-specific) and from greater focus on ensuring the maintenance of treatment gains.
AN  - 31623532
AU  - Romano,
AU  - E.
AU  - Weegar,
AU  - K.
AU  - Gallitto,
AU  - E.
AU  - Zak,
AU  - S.
AU  - Saini,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/1524838019881737
L1  - internal-pdf://0125973558/Romano-2021-Meta-Analysis on Interventions for.pdf
PY  - 2021
SP  - 728-738
T2  - Trauma Violence &amp; Abuse
TI  - Meta-Analysis on Interventions for Children Exposed to Intimate Partner Violence
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31623532
UR  - https://journals.sagepub.com/doi/10.1177/1524838019881737
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1524838019881737
VL  - 22
ER  -
TY  - JOUR
AB  - **CONTEXT:** Third-wave therapies have demonstrated efficacy as a treatment option for EDs in adulthood. Data on the suitability for EDs in adolescence are lacking. OBJECTIVE: To estimate the efficacy of third-wave interventions to reduce ED symptoms in adolescents in randomized controlled trials (RCTs) and uncontrolled studies. 

**DATA SOURCES**: We systematically reviewed the databases PubMed (1976-January 2021), PsycINFO (1943-January 2021), and the Cochrane database (1995-January 2021) for English-language articles on third-wave therapies. References were screened for further publications of interest. 

**STUDY SELECTION**: RCTs and pre-post studies without control group, comprising patients aged 11-21 years (mean age = 15.6 years) with an ED diagnosis (anorexia nervosa, bulimia nervosa, binge eating disorder, eating disorder not otherwise specified) investigating the efficacy of third-wave psychological interventions were included. Efficacy had to be evaluated according to the Eating Disorder Examination or Eating Disorder Examination-Questionnaire, the Eating Disorder Inventory-2, the Eating Disorder Inventory-3, or the Structured Interview for Anorexic and Bulimic Disorders for DSM-IV and ICD-10. The outcome assessed in the meta-analysis was the EDE total score.

**DATA EXTRACTION**: Independent extraction of data by two authors according to a pre-specified data extraction sheet and quality indicators. 

**DATA SYNTHESIS**: We identified 1000 studies after removal of duplicates, assessed the full texts of 48 articles for eligibility, and included 12 studies with a total of 487 participants (female 97.3%/male 2.6%) in the qualitative synthesis and seven studies in the meta-analysis. Articles predominantly reported uncontrolled pre-post trials of low quality, with only two published RCTs. Treatments focused strongly on dialectical behaviour therapy (n = 11). We found moderate effects of third-wave therapies on EDE total score interview/questionnaire for all EDs (d = - 0.67; z = - 5.53; CI95% = - 0.83 to - 0.59). Descriptively, the effects appeared to be stronger in patients with BN and BED. 

**CONCLUSION**: At this stage, it is not feasible to draw conclusions regarding the efficacy of third-wave interventions for the treatment of EDs in adolescence due to the low quality of the empirical evidence. Since almost all of the identified studies used DBT, it is unfortunately not possible to assess other third-wave treatments&#039; efficacy.
AN  - 34127069
AU  - Buerger,
AU  - A.
AU  - Vloet,
AU  - T.
AU  - D.
AU  - Haber,
AU  - L.
AU  - Geissler,
AU  - J.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s40479-021-00158-6
L1  - internal-pdf://1376150873/Buerger-2021-Third-wave interventions for eati.pdf
PY  - 2021
SP  - 20
T2  - Borderline Personality Disorder and Emotion Dysregulation
TI  - Third-wave interventions for eating disorders in adolescence - systematic review with meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34127069
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8201936/pdf/40479_2021_Article_158.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Disrupted social connections may negatively affect youth mental health. In contrast, sustained quality social connections (QSCs) can improve mental health outcomes. However, few studies have examined how these quality connections affect depression and anxiety outcomes within digital interventions, and conceptualization is limited. 

**OBJECTIVE**
The aim of this study is to conceptualize, appraise, and synthesize evidence on QSC within digital interventions (D-QSC) and the impact on depression and anxiety outcomes for young people aged 14-24 years. METHODS: A systematic scoping review and meta-analysis was conducted using the Joanna Briggs Institute methodological frameworks and guided by experts with lived experience. Reporting was guided by the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). The MEDLINE, Embase, PsycINFO, and CINAHL databases were searched against a comprehensive combination of key concepts on June 24, 2020. The search concepts included young people, digital intervention, depression, anxiety, and social connection. Google was also searched. A reviewer independently screened abstracts and titles and full text, and 9.99% (388/3882) of these were screened by a second reviewer. A narrative synthesis was used to structure the findings on indicators of D-QSC and mechanisms that facilitate the connection. Indicators of D-QSC from the included studies were synthesized to produce a conceptual framework. 

**RESULTS**
Of the 5715 publications identified, 42 (0.73%) were included. Among the included studies, there were 23,319 participants. Indicators that D-QSC was present varied and included relatedness, having a sense of belonging, and connecting to similar people. However, despite the variation, most of the indicators were associated with improved outcomes for depression and anxiety. Negative interactions, loneliness, and feeling ignored indicated that D-QSC was not present. In 24% (10/42) of the applicable studies, a meta-analysis showed a significant decrease in depression (-25.6%, 95% CI -0.352 to -0.160; P&lt;.001) and anxiety (-15.1%, 95% CI -0.251 to -0.051; P=.003) after a D-QSC. Digital mechanisms that helped create a quality connection included anonymity, confidentiality, and peer support. In contrast, mechanisms that hindered the connection included disconnection from the real world and inability to see body language. Data synthesis also identified a 5-component conceptual framework of D-QSC that included rapport, identity and commonality, valued interpersonal dynamic, engagement, and responded to and accepted. 

**CONCLUSIONS**
D-QSC is an important and underconsidered component for youth depression and anxiety outcomes. Researchers and developers should consider targeting improved QSC between clinicians and young people within digital interventions for depression. Future research should build on our framework to further examine relationships among individual attributes of QSC, various digital interventions, and different populations.
AN  - 34927592
AU  - Dewa,
AU  - L.
AU  - H.
AU  - Lawrance,
AU  - E.
AU  - Roberts,
AU  - L.
AU  - Brooks-Hall,
AU  - E.
AU  - Ashrafian,
AU  - H.
AU  - Fontana,
AU  - G.
AU  - Aylin,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/26584
L1  - internal-pdf://1270945201/pdf.cleaned.pdf
PY  - 2021
SP  - e26584
T2  - Journal of Medical Internet Research
TI  - Quality Social Connection as an Active Ingredient in Digital Interventions for Young People With Depression and Anxiety: Systematic Scoping Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34927592
VL  - 23
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Cognitive-behavioural therapy aims to increase quality of life by changing cognitive and behavioural factors that maintain problematic symptoms. A previous overview of cognitive-behavioural therapy systematic reviews suggested that cognitive-behavioural therapy was effective for many conditions. However, few of the included reviews synthesised randomised controlled trials.

OBJECTIVES: 
This project was undertaken to map the quality and gaps in the cognitive-behavioural therapy systematic review of randomised controlled trial evidence base. Panoramic meta-analyses were also conducted to identify any across-condition general effects of cognitive-behavioural therapy.DATA SOURCES: The overview was designed with cognitive-behavioural therapy patients, clinicians and researchers. The Cochrane Library, MEDLINE, EMBASE, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Child Development &amp; Adolescent Studies, Database of Abstracts of Reviews of Effects and OpenGrey databases were searched from 1992 to January 2019.

REVIEW METHODS: 
Study inclusion criteria were as follows: (1) fulfil the Centre for Reviews and Dissemination criteria; (2) intervention reported as cognitive-behavioural therapy or including one cognitive and one behavioural element; (3) include a synthesis of cognitive-behavioural therapy trials; (4) include either health-related quality of life, depression, anxiety or pain outcome; and (5) available in English. Review quality was assessed with A MeaSurement Tool to Assess systematic Reviews (AMSTAR)-2. Reviews were quality assessed and data were extracted in duplicate by two independent researchers, and then mapped according to condition, population, context and quality. The effects from high-quality reviews were pooled within condition groups, using a random-effect panoramic meta-analysis. If the across-condition heterogeneity was I &lt;sup&gt;2&lt;/sup&gt; &lt; 75%, we pooled across conditions. Subgroup analyses were conducted for age, delivery format, comparator type and length of follow-up, and a sensitivity analysis was performed for quality.

RESULTS: 
A total of 494 reviews were mapped, representing 68% (27/40) of the categories of the International Classification of Diseases, Eleventh Revision, Mortality and Morbidity Statistics. Most reviews (71%, 351/494) were of lower quality. Research on older adults, using cognitive-behavioural therapy preventatively, ethnic minorities and people living outside Europe, North America or Australasia was limited. Out of 494 reviews, 71 were included in the primary panoramic meta-analyses. A modest effect was found in favour of cognitive-behavioural therapy for health-related quality of life (standardised mean difference 0.23, 95% confidence interval 0.05 to 0.41, prediction interval -0.05 to 0.50, I &lt;sup&gt;2&lt;/sup&gt; = 32%), anxiety (standardised mean difference 0.30, 95% confidence interval 0.18 to 0.43, prediction interval -0.28 to 0.88, I &lt;sup&gt;2&lt;/sup&gt; = 62%) and pain (standardised mean difference 0.23, 95% confidence interval 0.05 to 0.41, prediction interval -0.28 to 0.74, I &lt;sup&gt;2&lt;/sup&gt; = 64%) outcomes. All condition, subgroup and sensitivity effect estimates remained consistent with the general effect. A statistically significant interaction effect was evident between the active and non-active comparator groups for the health-related quality-of-life outcome. A general effect for depression outcomes was not produced as a result of considerable heterogeneity across reviews and conditions.

LIMITATIONS: 
Data extraction and analysis were conducted at the review level, rather than returning to the individual trial data. This meant that the risk of bias of the individual trials could not be accounted for, but only the quality of the systematic reviews that synthesised them.

CONCLUSION: 
Owing to the consistency and homogeneity of the highest-quality evidence, it is proposed that cognitive-behavioural therapy can produce a modest general, across-condition benefit in health-related quality-of-life, anxiety and pain outcomes.

FUTURE WORK: 
Future research should focus on how the modest effect sizes seen with cognitive-behavioural therapy can be increased, for example identifying alternative delivery formats to increase adherence and reduce dropout, and pursuing novel methods to assess intervention fidelity and quality.

STUDY REGISTRATION: 
This study is registered as PROSPERO CRD42017078690.FUNDING: This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 25, No. 9. See the NIHR Journals Library website for further project information.
AD  - Fordham, Beth. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.Sugavanam, Thavapriya. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.Edwards, Katherine. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.Hemming, Karla. Institute of Applied Health Research, University of Birmingham, Birmingham, UK.Howick, Jeremy. Faculty of Philosophy, University of Oxford, Oxford, UK.Copsey, Bethan. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.Lee, Hopin. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.Kaidesoja, Milla. Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.Kirtley, Shona. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.Hopewell, Sally. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.das Nair, Roshan. Department of Psychiatry and Applied Psychology, University of Nottingham, Nottingham, UK.das Nair, Roshan. Institute of Mental Health, Nottinghamshire Healthcare NHS Foundation Trust, Nottingham, UK.Howard, Robert. Division of Psychiatry, University College London, London, UK.Stallard, Paul. Department for Health, University of Bath, Bath, UK.Hamer-Hunt, Julia. Public and patient representative, Oxford, UK.Cooper, Zafra. Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.Lamb, Sarah E. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.Lamb, Sarah E. College of Medicine and Health, University of Exeter, Exeter, UK.
AN  - 33629950
AU  - Fordham,
AU  - B.
AU  - Sugavanam,
AU  - T.
AU  - Edwards,
AU  - K.
AU  - Hemming,
AU  - K.
AU  - Howick,
AU  - J.
AU  - Copsey,
AU  - B.
AU  - Lee,
AU  - H.
AU  - Kaidesoja,
AU  - M.
AU  - Kirtley,
AU  - S.
AU  - Hopewell,
AU  - S.
AU  - das
AU  - Nair,
AU  - R.
AU  - Howard,
AU  - R.
AU  - Stallard,
AU  - P.
AU  - Hamer-Hunt,
AU  - J.
AU  - Cooper,
AU  - Z.
AU  - Lamb,
AU  - S.
AU  - E.
DA  - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3310/hta25090
DP  - Ovid Technologies
J2  - Health Technol Assess
L1  - internal-pdf://3746214040/Fordham-2021.pdf
LA  - English
M3  - Systematic Review
N1  - Fordham, BethSugavanam, ThavapriyaEdwards, KatherineHemming, KarlaHowick, JeremyCopsey, BethanLee, HopinKaidesoja, MillaKirtley, ShonaHopewell, Sallydas Nair, RoshanHoward, RobertStallard, PaulHamer-Hunt, JuliaCooper, ZafraLamb, Sarah E
PY  - 2021
SP  - 1-378
T2  - Health Technology Assessment (Winchester, England)
TI  - Cognitive-behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33629950
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33629950&amp;id=doi:10.3310%2Fhta25090&amp;issn=1366-5278&amp;isbn=&amp;volume=25&amp;issue=9&amp;spage=1&amp;pages=1-378&amp;date=2021&amp;title=Health+Technology+Assessment+%28Winchester%2C+England%29&amp;atitle=Cognitive-behavioural+therapy+for+a+variety+of+conditions%3A+an+overview+of+systematic+reviews+and+panoramic+meta-analysis.&amp;aulast=Fordham&amp;pid=%3Cauthor%3EFordham+B%3C%2Fauthor%3E%3CAN%3E33629950%3C%2FAN%3E%3CDT%3ESystematic+Review%3C%2FDT%3E
VL  - 25
ER  -
TY  - JOUR
AB  - **Introduction**: Intimate partner violence and sexual violence are widespread and often occur early in life. This systematic review examines the effectiveness of interventions for primary prevention of intimate partner violence and sexual violence among youth. 

**Method(s)**: Studies were identified from 2 previous systematic reviews and an updated search (January 2012-June 2016). Included studies were implemented among youth, conducted in high-income countries, and aimed to prevent or reduce the perpetration of intimate partner violence or sexual violence. In 2016-2017, Guide to Community Preventive Services (Community Guide) methods were used to assess effectiveness as determined by perpetration, victimization, or bystander action. When heterogeneity of outcomes prevented usual Community Guide methods, the team systematically applied criteria for favorability (statistically significant at p&lt;0.05 or approaching significance at p&lt;0.10) and consistency (75% of results in the same direction). 

**Result(s)**: A total of 28 studies (32 arms) met inclusion and quality of execution criteria. Interventions used combinations of teaching healthy relationship skills, promoting social norms to protect against violence, or creating protective environments. Overall, 18 of 24 study arms reported favorable results on the basis of the direction of effect for decreasing perpetration; however, favorability for bystander action diminished with longer follow-up. Interventions did not demonstrate consistent results for decreasing victimization. A bridge search conducted during Fall 2020 confirmed these results. 

**Discussion(s)**: Interventions for the primary prevention of intimate partner violence and sexual violence are effective in reducing perpetration. Increasing bystander action may require additional follow-up as effectiveness diminishes over time. Findings may inform researchers, school personnel, public health, and other decision makers about effective strategies to prevent intimate partner violence and sexual violence among youth. Copyright &copy; 2021
AN  - 2015526251
AU  - Finnie,
AU  - R.
AU  - K.
AU  - C.
AU  - Okasako-Schmucker,
AU  - D.
AU  - L.
AU  - Buchanan,
AU  - L.
AU  - Carty,
AU  - D.
AU  - Wethington,
AU  - H.
AU  - Mercer,
AU  - S.
AU  - L.
AU  - Basile,
AU  - K.
AU  - C.
AU  - DeGue,
AU  - S.
AU  - Niolon,
AU  - P.
AU  - H.
AU  - Bishop,
AU  - J.
AU  - Titus,
AU  - T.
AU  - Noursi,
AU  - S.
AU  - Dickerson,
AU  - S.
AU  - A.
AU  - Whitaker,
AU  - D.
AU  - Swider,
AU  - S.
AU  - Remington,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.amepre.2021.06.021
L1  - internal-pdf://0428714799/Finnie-2021.pdf
PY  - 2021
T2  - American Journal of Preventive Medicine.
TI  - Intimate Partner and Sexual Violence Prevention Among Youth: A Community Guide Systematic Review
UR  - http://www.elsevier.com/locate/amepre
UR  - https://www.ajpmonline.org/article/S0749-3797(21)00418-9/fulltext
ER  -
TY  - JOUR
AB  - Many interventions designed to improve educational outcomes for students with autism spectrum disorder (ASD) have been published, yet there has not been an adequate review of interventions in school settings assessed against student outcomes. We reviewed empirical literature published 2000 to June 2019 that evaluated school-based interventions applied to students formally diagnosed, with an IQ &gt; 70, and who were attending kindergarten/pre-school, primary, or secondary school. Interventions most commonly targeted skills in six areas: academic skills, on-task behaviour, play behaviour, social cognition, social interaction, and verbal skills. Results indicated significant improvement in each area. Generalization and maintenance were not consistently evaluated. Few studies included female participants and few reported on participant race; of those that did, the majority were Caucasian. Further research, utilizing larger samples and more stringent statistical approaches, is needed to identify the most efficient and effective interventions to improve educational outcomes for this population.
AN  - WOS:000691195400001
AU  - Macmillan,
AU  - C.
AU  - M.
AU  - Pecora,
AU  - L.
AU  - A.
AU  - Ridgway,
AU  - K.
AU  - Hooley,
AU  - M.
AU  - Thomson,
AU  - M.
AU  - Dymond,
AU  - S.
AU  - Donaldson,
AU  - E.
AU  - Mesibov,
AU  - G.
AU  - B.
AU  - Stokes,
AU  - M.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40489-021-00289-0
L1  - internal-pdf://0273104027/Macmillan-An Evaluation of Education-Based Int.pdf
PY  - 2021
SP  - 19
T2  - Review Journal Of Autism And Developmental Disorders
TI  - An Evaluation of Education-Based Interventions for Students with Autism Spectrum Disorders Without Intellectual Disability: a Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000691195400001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-021-00289-0.pdf
ER  -
TY  - JOUR
AB  - **PURPOSE: **
Comprehensive school-based health services were reviewed as part of preparing World Health Organization guidelines. 

**METHODS: **
Six databases were searched for controlled trials with schoolchildren aged 5-19 years, involving school-linked health services incorporating 4 of 7 health areas. 

**RESULTS: **
Seventeen quasi-experimental studies conducted in high-income countries found school health services associated with reductions in suicide planning (male: 7.1% vs. 7.7%, p &lt; .01), hospitalization (relative risks 3.403, 95% confidence interval [CI] 1.536 to 8.473, p &lt; .05), emergency department visits (odds ratio .85, 95% CI .75 to .95, p = .006), school absence (odds ratio .78, 95% CI .69 to .87, p &lt; .0001), carrying weapons (male: 16.1% vs. 25.1%, p &lt; .01), fighting (male: 32.6% vs. 43.1%, p &lt; .01), sexual activity (53.5% vs. 60.5%, p &lt; .05), drinking alcohol (60.1% vs. 70.5%, p &lt; .001), using drugs (28.0% vs. 38.3%, p &lt; .001), and physical activity (female: 57.4% vs. 50.4%, p &lt; .01). They can be cost-saving, were also associated with smoking and less contraceptive use, and had no effect on depression prevalence. Acceptability/satisfaction was good. The certainty of evidence was low to moderate. Heterogeneity was high for some outcomes. 

**CONCLUSIONS: **
Results suggest moderate desirable and trivial undesirable effects of school health services in high-income countries. This article compiles evidence on effectiveness, cost-effectiveness, and acceptability into one review, enabling decision-makers to consider all essential factors. 

(PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-88032-001
AU  - Montgomery,
AU  - P.
AU  - Knerr,
AU  - W.
AU  - Ross,
AU  - D.
AU  - A.
AU  - Patterson,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jadohealth.2021.08.010
L1  - internal-pdf://2556832214/Montgomery-2021-The effectiveness and acceptab.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Journal of Adolescent Health
TI  - The effectiveness and acceptability of comprehensive and multicomponent school health services: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-88032-001
UR  - https://www.jahonline.org/article/S1054-139X(21)00406-7/fulltext
UR  - https://www.jahonline.org/article/S1054-139X(21)00406-7/pdf
ER  -
TY  - JOUR
AB  - Due to the negative impact of trauma exposure, effective treatments are necessary to prevent and improve negative trauma-related outcomes. Cognitive behavioral therapy (CBT) is considered an efficacious treatment for children and adolescents exposed to traumatic events. Despite the various meta-analyses that have examined trauma treatments, there is a paucity of research on the moderating variables that may impact treatment outcomes. 

This meta-analytic CBT study addressed those limitations by examining the moderating effects of treatment components on outcomes. A search identified 94 CBT studies with 97 relevant effect sizes for children and adolescents exposed to traumatic events. Consistent with prior meta-analytic studies, CBT was shown to be effective for trauma-exposed youth. CBT subtreatments did not produce significantly different results from one another. Moderators shown to significantly impact CBT treatment outcomes for posttraumatic stress symptom were trauma type, Q = 24.09, p = .004, ds = -0.22 to -1.42, and gender, Q = 10.68, p = .005, ds = -0.53 to -1.36, whereas moderators shown to impact treatment outcomes for depression were study design, Q = 10.95, p = .004, ds = -0.26 to -0.50, and treatment setting, Q = 10.98, p = .004, ds = -0.31 to -0.56. The implications of these findings for research and practice are discussed.
AN  - 34800050
AU  - Yohannan,
AU  - J.
AU  - Carlson,
AU  - J.
AU  - S.
AU  - Volker,
AU  - M.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/jts.22755
L1  - internal-pdf://3790260737/Yohannan-2021.pdf
PY  - 2021
SP  - 20
T2  - Journal of Traumatic Stress
TI  - Cognitive behavioral treatments for children and adolescents exposed to traumatic events: A meta-analysis examining variables moderating treatment outcomes
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34800050
UR  - https://onlinelibrary.wiley.com/doi/10.1002/jts.22755
VL  - 20
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: The objective of this study was to systematically review existing empirical evidence on the effectiveness of trauma-specific treatment for justice-involved adolescents and evaluate the impact of the interventions on the reduction of posttraumatic stress disorder (PTSD) symptoms, co-occurring mental health symptoms, and juvenile justice-related outcomes. 

**METHOD**: A systematic literature search was conducted using a four-step process. Studies were included if they used a manualized, trauma-specific treatment with at least one control or comparison group and a sample comprised exclusively of justice-involved adolescents. 

**RESULTS**: In total, 1,699 unique records were identified, and 56 full-text articles were reviewed, of which 7 met the criteria for inclusion. Trauma-specific interventions led to a decrease in PTSD symptoms compared with a control group in four of seven studies, and two studies also demonstrated a reduction in trauma-related depressive symptoms. Finally, juvenile justice-related outcomes were measured in only four studies, with one study finding moderately reduced rates of delinquent behavior and recidivism following trauma-specific treatment. 

**CONCLUSIONS**: The results from this systematic review suggest that trauma-specific treatment interventions have promising effects for justice-involved adolescents. However, the results reveal a dearth of quality intervention research for treating youths with histories of trauma in the justice system. Significant gaps in the literature are highlighted, and suggestions for future directions are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
AN  - 34410809
AU  - Baetz,
AU  - C.
AU  - L.
AU  - Branson,
AU  - C.
AU  - E.
AU  - Weinberger,
AU  - E.
AU  - Rose,
AU  - R.
AU  - E.
AU  - Petkova,
AU  - E.
AU  - Horwitz,
AU  - S.
AU  - M.
AU  - Hoagwood,
AU  - K.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/tra0001073
L1  - internal-pdf://1326325755/Baetz-2021-The effectiveness of PTSD treatment.pdf
PY  - 2021
SP  - 19
T2  - Psychological Trauma:Theory, Pesearch, Practice and Policy
TI  - The effectiveness of PTSD treatment for adolescents in the juvenile justice system: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34410809
VL  - 19
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: To evaluate effect of enteral zinc supplementation on growth and neurodevelopmental outcomes of preterm infants.

**STUDY DESIGN**: A systematic review and meta-analysis of randomized-controlled trials (RCTs) examining growth and neurodevelopmental outcomes after zinc supplementation in preterm infants.

**RESULTS**: Of eight RCTs involving 742 infants included, seven reported growth anthropometrics at 3-6 months corrected age (CA) and two reported neurodevelopmental outcomes at 6-12 months CA. Zinc supplementation was associated with increased weight z-score (weighted mean difference (WMD) = 0.50; 95% CI 0.23-0.76, heterogeneity I&lt;sup&gt;2&lt;/sup&gt; = 89.1%; P &lt; 0.01), length z-score (WMD = 1.12; 95% CI 0.63-1.61, heterogeneity I&lt;sup&gt;2&lt;/sup&gt; = 96.0%; P &lt; 0.01) and motor developmental score (WMD = 9.54; 95% CI 6.6-12.4 heterogeneity I&lt;sup&gt;2&lt;/sup&gt; = 0%; P = 0.52). There was no effect on head circumference and total developmental score. Evidence is &quot;moderate&quot; certainty for weight and length and &quot;very low&quot; certainty for neurodevelopment.CONCLUSION: Zinc supplementation may enhance weight gain and linear growth in preterm infants. There is a lack of data about relationship between zinc supplementation and neurodevelopment.
AD  - Alshaikh, Belal. Neonatal Nutrition and Gastroenterology Program, University of Calgary, Calgary, AB, Canada. balshaik@ucalgary.ca.Alshaikh, Belal. Community Health Sciences, Institute of Public Health, Alberta Children&#039;s Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. balshaik@ucalgary.ca.Abo Zeed, Moaaz. McMaster University, Hamilton, AB, Canada.Yusuf, Kamran. Neonatal Nutrition and Gastroenterology Program, University of Calgary, Calgary, AB, Canada.Guin, Madhusudan. Neonatal Nutrition and Gastroenterology Program, University of Calgary, Calgary, AB, Canada.Fenton, Tanis. Community Health Sciences, Institute of Public Health, Alberta Children&#039;s Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.Fenton, Tanis. Nutrition Services, Alberta Health Services, Calgary, AB, Canada.
AN  - 34006967
AU  - Alshaikh,
AU  - B.
AU  - Abo
AU  - Zeed,
AU  - M.
AU  - Yusuf,
AU  - K.
AU  - Guin,
AU  - M.
AU  - Fenton,
AU  - T.
DA  - May 18
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1038/s41372-021-01094-7
DP  - Ovid Technologies
J2  - J Perinatol
L1  - internal-pdf://0281162174/Alshaikh-2021.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingMayAlshaikh, BelalAbo Zeed, MoaazYusuf, KamranGuin, MadhusudanFenton, Tanis
PY  - 2021
SP  - 18
T2  - Journal of Perinatology
TI  - Effect of enteral zinc supplementation on growth and neurodevelopment of preterm infants: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34006967
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:34006967&amp;id=doi:10.1038%2Fs41372-021-01094-7&amp;issn=0743-8346&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+Perinatology&amp;atitle=Effect+of+enteral+zinc+supplementation+on+growth+and+neurodevelopment+of+preterm+infants%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Alshaikh&amp;pid=%3Cauthor%3EAlshaikh+B%3C%2Fauthor%3E%3CAN%3E34006967%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.nature.com/articles/s41372-021-01094-7
UR  - https://www.nature.com/articles/s41372-021-01094-7.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - **Objective**
To examine the evidence for efficacy of phosphatidylserine for symptoms of attention-deficit/hyperactivity disorder (ADHD) in children. 

**Methods**
Medline, Cochrane Library, and ClinicalTrials.gov were searched from inception through August 2020. Studies of any design that assessed phosphatidylserine supplementation for children aged &lt;=18 years with a diagnosis of ADHD were included in the systematic review; only randomized clinical trials were included in the meta-analysis. Standardized mean differences and 95% confidence intervals (CIs) were calculated, and the heterogeneity of the studies was estimated using I&lt;sup&gt;2&lt;/sup&gt;. The overall quality of the evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation tool. 

**Results**
Four studies met the inclusion criteria for the narrative review (n = 344) and three for the meta-analysis (n = 216). Results of the meta-analysis showed a statistically significant effect of 200-300 mg/day of phosphatidylserine on symptoms of inattention relative to placebo (effect size [ES] 0.36; 95% CI: 0.07 to 0.64; p = 0.01). The effects of phosphatidylserine on overall symptoms of ADHD (ES 0.76; 95% CI: -0.07 to 1.60; p = 0.07) and hyperactivity-impulsivity (ES 0.24; 95% CI: -0.04 to 0.53; p = 0.09) were not statistically significant. 

**Conclusions**
Preliminary evidence suggests that phosphatidylserine may be effective for reducing symptoms of inattention in children with ADHD, although the quality of the evidence is low and additional research in this area is warranted.
AD  - Bruton, Alisha. Department of Psychiatry, Oregon Health and Science University, Portland, OR, USA.Bruton, Alisha. Helfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.Nauman, Joy. Helfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.Hanes, Douglas. Helfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.Gard, Melissa. Oregon Institute of Technology, Klamath Falls, OR, USA.Senders, Angela. Helfgott Research Institute, National University of Natural Medicine, Portland, OR, USA.
AN  - 33539192
AU  - Bruton,
AU  - A.
AU  - Nauman,
AU  - J.
AU  - Hanes,
AU  - D.
AU  - Gard,
AU  - M.
AU  - Senders,
AU  - A.
DA  - Feb 04
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1089/acm.2020.0432
DP  - Ovid Technologies
J2  - J Altern Complement Med
L1  - internal-pdf://1271044204/Bruton-2021.pdf
LA  - English
N1  - Using Smart Source ParsingFebBruton, AlishaNauman, JoyHanes, DouglasGard, MelissaSenders, Angela
PY  - 2021
SP  - 04
T2  - Journal of Alternative &amp; Complementary Medicine
TI  - Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33539192
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33539192&amp;id=doi:10.1089%2Facm.2020.0432&amp;issn=1075-5535&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+Alternative+%26+Complementary+Medicine&amp;atitle=Phosphatidylserine+for+the+Treatment+of+Pediatric+Attention-Deficit%2FHyperactivity+Disorder%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Bruton&amp;pid=%3Cauthor%3EBruton+A%3C%2Fauthor%3E%3CAN%3E33539192%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.liebertpub.com/doi/10.1089/acm.2020.0432
UR  - https://www.liebertpub.com/doi/pdfplus/10.1089/acm.2020.0432
VL  - 04
ER  -
TY  - JOUR
AB  - A large number of computer-based training programs have been developed as an intervention to help individuals with autism spectrum disorders (ASD) improve their facial emotion recognition ability, as well as social skills. However, it is unclear to what extent these facial emotion training programs can produce beneficial, long-lasting, and generalizable results. 

Using standard meta-analytic techniques, we investigated the effects of facial emotion training including generalization and maintenance restricted to randomized control trial studies comprising a total of 595 individuals with ASD. Our findings revealed that the intervention resulted in a robust improvement in emotion recognition for individuals receiving training compared with controls. However, while there was also some evidence for generalization of training effects, the small number of studies which conducted follow-ups and assessed social skills reported that improvements were not maintained and there was no evidence for general improvement in social skills. 

Overall, the analysis revealed a medium effect size in training improvement indicating that facial emotion training may be an effective method for enhancing emotion recognition skills in ASD although more studies are required to assess maintenance of effects and possible general improvements in social skills. Lay summary Facial emotion training as an intervention may be a potential way to help improve emotion recognition in autism spectrum disorder (ASD), however robust empirical support for its efficacy has not been sufficiently established. Here, we conducted a meta-analysis of previous studies to summarize the effects of facial emotion training on ASD. 

Our results show that the training produces a robust improvement in subsequent emotion recognition, while maintenance and generalization effects still need further investigation. To date, no experimentally verified improvements in social skills have been reported.
AN  - WOS:000674373100001
AU  - Zhang,
AU  - Q.
AU  - Q.
AU  - Wu,
AU  - R.
AU  - J.
AU  - Zhu,
AU  - S.
AU  - Y.
AU  - Le,
AU  - J.
AU  - Chen,
AU  - Y.
AU  - S.
AU  - Lan,
AU  - C.
AU  - M.
AU  - Yao,
AU  - S.
AU  - X.
AU  - Zhao,
AU  - W.
AU  - H.
AU  - Kendrick,
AU  - K.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/aur.2565
L1  - internal-pdf://0797112574/Zhang-Facial emotion training as an interventi.pdf
PY  - 2021
SP  - 14
T2  - Autism Research
TI  - Facial emotion training as an intervention in autism spectrum disorder: A meta-analysis of randomized controlled trials
UR  - &lt;Go to ISI&gt;://WOS:000674373100001
UR  - https://onlinelibrary.wiley.com/doi/10.1002/aur.2565
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aur.2565?download=true
ER  -
TY  - JOUR
AB  - <b>Background</b>: Many children and young people (CYP) presenting with mental health crises are admitted to hospital due to concerns around illness severity and risk. Whilst inpatient admissions have an important role for such children, there are a number of burdens associated with them, and safe avoidance of admissions is favourable. We systematically reviewed the literature for studies of interventions reported as alternatives to a hospital admission in CYP presenting with mental health crises, in any inpatient setting. 

<b>Methods</b>: Three databases (PsychInfo, PubMed and Web of Science) were searched for peer-reviewed papers in October 2020, with an updated search in May 2021. 

<b>Results</b>: We identified 19 papers of interventions delivered in the emergency department, the home, outside of home but outside of clinics and in hospital clinics. The quality of most included studies was low, with less than half being randomised controlled trials and only half of these at low risk of bias. The best quality studies and greatest evidence for efficacy came from in-home interventions, in particular multisystemic therapy, which improved psychological outcomes, and though a large number of CYP still ended up being admitted, there appeared to be decreased length of stay. 

<b>Conclusions</b>: Overall, we could not recommend a particular intervention as an alternative to inpatient admission; however, our review describes benefits across a range of types of interventions that might be considered in multi-modal treatments. We also provide recommendations for future research, in particular the evaluation of new interventions as they emerge.
AN  - 34836461
AU  - Clisu,
AU  - D.
AU  - A.
AU  - Layther,
AU  - I.
AU  - Dover,
AU  - D.
AU  - Viner,
AU  - R.
AU  - M.
AU  - Read,
AU  - T.
AU  - Cheesman,
AU  - D.
AU  - Hodges,
AU  - S.
AU  - Hudson,
AU  - L.
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/13591045211044743
L1  - internal-pdf://1660002807/Alternatives to mental health admissions-2021.pdf
PY  - 2021
SP  - 13591045211044743
T2  - Clinical Child Psychology &amp; Psychiatry
TI  - Alternatives to mental health admissions for children and adolescents experiencing mental health crises: A systematic review of the literature
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34836461
UR  - https://journals.sagepub.com/doi/pdf/10.1177/13591045211044743
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Anxiety disorders are common in children and youth. Also, in prevention, be it universal, selective or indicated, economic evaluation supports decision-making in the allocation of scarce resources. This review identified and summarised the existing evidence of economic evaluations for the prevention of anxiety disorders in children and adolescents. 

**METHODS: ** 
A systematic search was conducted on the EBSCO, Scopus, Web of Science, ProQuest, Cochrane and PubMed databases. We included studies that focused on children and adolescents under 18 years of age, aimed to prevent anxiety disorders and presented an incremental analysis of costs and effectiveness. A registered checklist was used that assessed the quality of the included articles.

**RESULTS: **
The search yielded 1697 articles. Five articles were included in this review. Three were RCT-based, and two were model-based studies. Out of five included interventions, one was a universal school-based intervention, two selective interventions and two indicated interventions. Universal school-based prevention of anxiety was not cost-effective compared with usual teaching. Selective parent training and indicative child- and parent-focused CBT prevention were likely cost-effective compared with usual care or doing nothing. 

**CONCLUSION: **
Parent education and cognitive behaviour therapy interventions can be cautiously interpreted as being a cost-effective way of preventing anxiety in children and adolescents. However, the evidence is weakly related to cost-effectiveness as there are only a few studies, with relatively small sample sizes and short follow-ups.
AN  - 34472208
AU  - Anna-Kaisa,
AU  - V.
AU  - Virpi,
AU  - K.
AU  - K.
AU  - Mervi,
AU  - R.
AU  - Elisa,
AU  - R.
AU  - Terhi,
AU  - L.
AU  - Marjo,
AU  - K.
AU  - Andre,
AU  - S.
AU  - Eila,
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/camh.12505
L1  - internal-pdf://0211227691/Anna-Kaisa-2021-Review_ Economic evidence of p.pdf
PY  - 2021
SP  - 01
T2  - Child &amp; Adolescent Mental Health
TI  - Review: Economic evidence of preventive interventions for anxiety disorders in children and adolescents - a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34472208
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/camh.12505?download=true
VL  - 01
ER  -
TY  - JOUR
AB  - **Background**
Depression is one of the most common morbidities of the postnatal period. It has been associated with adverse outcomes for women, children, the wider family and society as a whole. Treatment is with psychosocial interventions or antidepressant medication, or both. The aim of this review is to evaluate the effectiveness of different antidepressants and to compare their effectiveness with placebo, treatment as usual or other forms of treatment. This is an update of a review last published in 2014.

**Objectives**
To assess the effectiveness and safety of antidepressant drugs in comparison with any other treatment (psychological, psychosocial, or pharmacological), placebo, or treatment as usual for postnatal depression.

**Search methods**
We searched Cochrane Common Mental Disorders&#039;s Specialized Register, CENTRAL, MEDLINE, Embase and PsycINFO in May 2020. We also searched international trials registries and contacted experts in the field.

**Selection criteria**
We included randomised controlled trials (RCTs) of women with depression during the first 12 months postpartum that compared antidepressant treatment (alone or in combination with another treatment) with any other treatment, placebo or treatment as usual.

**Data collection and analysis**
Two review authors independently extracted data from the study reports. We requested missing information from study authors wherever possible. We sought data to allow an intention‐to‐treat analysis. Where we identified sufficient comparable studies we pooled data and conducted random‐effects meta‐analyses.

**Main results**
We identified 11 RCTs (1016 women), the majority of which were from English‐speaking, high‐income countries; two were from middle‐income countries. Women were recruited from a mix of community‐based, primary care, maternity and outpatient settings. Most studies used selective serotonin reuptake inhibitors (SSRIs), with treatment duration ranging from 4 to 12 weeks.

Meta‐analysis showed that there may be a benefit of SSRIs over placebo in response (55% versus 43%; pooled risk ratio (RR) 1.27, 95% confidence interval (CI) 0.97 to 1.66); remission (42% versus 27%; RR 1.54, 95% CI 0.99 to 2.41); and reduced depressive symptoms (standardised mean difference (SMD) &minus;0.30, 95% CI &minus;0.55 to &minus;0.05; 4 studies, 251 women), at 5 to 12 weeks&#039; follow‐up. We were unable to conduct meta‐analysis for adverse events due to variation in the reporting of this between studies. There was no evidence of a difference between acceptability of SSRI and placebo (27% versus 27%; RR 1.10, 95% CI 0.74 to 1.64; 4 studies; 233 women). The certainty of all the evidence for SSRIs was low or very low due to the small number of included studies and a number of potential sources of bias, including high rates of attrition.

There was insufficient evidence to assess the efficacy of SSRIs compared with other classes of antidepressants and of antidepressants compared with other pharmacological interventions, complementary medicines, psychological and psychosocial interventions or treatment as usual. A substantial proportion of women experienced adverse effects but there was no evidence of differences in the number of adverse effects between treatment groups in any of the studies. Data on effects on children, including breastfed infants, parenting, and the wider family were limited, although no adverse effects were noted.

**Authors&#039; conclusions**
There remains limited evidence regarding the effectiveness and safety of antidepressants in the management of postnatal depression, particularly for those with more severe depression. We found low‐certainty evidence that SSRI antidepressants may be more effective in treating postnatal depression than placebo as measured by response and remission rates. However, the low certainty of the evidence suggests that further research is very likely to have an important impact on our effect estimate. There is a continued imperative to better understand whether, and for whom, antidepressants or other treatments are more effective for postnatal depression, and whether some antidepressants are more effective or better tolerated than others.

In clinical practice, the findings of this review need to be contextualised by the extensive broader literature on antidepressants in the general population and perinatal clinical guidance, to inform an individualised risk‐benefit clinical decision. Future RCTs should focus on larger samples, longer follow‐up, comparisons with alternative treatment modalities and inclusion of child and parenting outcomes.
AU  - Brown,
AU  - J.
AU  - V.
AU  - E.
AU  - Wilson,
AU  - C.
AU  - A.
AU  - Ayre,
AU  - K.
AU  - Robertson,
AU  - L.
AU  - South,
AU  - E.
AU  - Molyneaux,
AU  - E.
AU  - Trevillion,
AU  - K.
AU  - Howard,
AU  - L.
AU  - M.
AU  - Khalifeh,
AU  - H.
DA  - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013560.pub2
L1  - internal-pdf://2863313519/Brown_et_al-2021-Cochrane_Database_of_Systemat.pdf
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - Antidepressant treatment for postnatal depression
ER  -
TY  - JOUR
AB  - **Background**: Autistic transition-aged youth and young adults face many societal barriers to competitive integrated employment (CIE). Existing evidence-based practices (EBPs) for autistic individuals, such as video modeling (VM), may be a viable on-the-job training method to enhance employment experiences and outcomes for this population. 

**Methods**: The purpose of this meta-analysis was to synthesize VM studies to teach job skills for autistic individuals. We applied the Council for Exceptional Children&#039;s (CEC) Standards for Evidence-Based Practices in Special Education to evaluate the methodological rigor of included studies using a weighted coding scheme. We further evaluated methodologically sound studies by calculating an omnibus Tau-U effect size. Results: Twenty articles met our inclusion criteria, and 11 of those studies were classified as methodologically sound according to the CEC&#039;s criteria. 

**Results** indicate that VM is an EBP to improve job skills of autistic individuals. The overall effect size for methodologically sound studies was strong (0.91), but most studies occurred in contrived or school-based employment settings rather than CIE settings in the local labor market. 

**Conclusions**: Employers, transition professionals, and related service providers can consider VM a viable method to teach job skills to autistic employees. However, additional research conducted in CIE settings is needed to better understand the effects of VM in contexts where autistic employees earn regular wages. Lay summary Why was this study done? Autistic adolescents and adults often experience barriers obtaining employment in their local communities. They may also benefit from on-the-job supports for successful employment. Video modeling is one intervention technique that has been used to teach a variety of skills to autistic individuals. Video modeling involves creating short video clips that show the person how to do specific skills or tasks. We wanted to learn about how video modeling has been used to teach job skills to autistic employees. What was the purpose of this study? The purpose of this study was to evaluate the quality of research studies that used video modeling to teach job skills to autistic employees. Understanding how video modeling interventions can be used in employment settings may help autistic employees have more positive work experiences. What did the researchers do? The researchers analyzed the video modeling research studies with autistic participants aged 14 years or older. We evaluated the quality of each study, type of employment setting, type of job skill, and how much the job skills improved. We used a criteria established by a professional organization, the Council for Exceptional Children, to evaluate the quality of the research studies. What were the results of the study? We analyzed 20 research studies and found that video modeling was an overall effective intervention to teach job skills to autistic adolescents and adults. However, most of the studies focused on general job tasks rather than employment-related social skills. In addition, most of the studies were conducted in employment settings where the autistic employees did not earn regular wages, such as school settings or internships. We encourage future researchers to study how video modeling can be used to promote competitive integrated employment in community settings. What do these findings add to what was already known? Prior research studies have used video modeling to teach skills such as academic, play, and social skills to autistic children and youth. This study showed us that video modeling is an effective intervention to teach job skills to autistic adolescents and adults. What are the potential weaknesses of the study? There are disagreements about how to evaluate the quality of research studies in the field of special education. We used a popular criterion by the Council for Exceptional Children organization, but our results may be different from other researchers. We also did not find a large number of studies, so some of our findings should be considered with caution. How will these findings help autistic adults now or in the future? These findings demonstrate that video modeling is an effective on-the-job training method for autistic employees. Autistic adults can use video modeling at work to learn new job skills. Employers, job coaches, and secondary transition professionals could use brief videos to support autistic employees.
AN  - WOS:000644507900001
AU  - Bross,
AU  - L.
AU  - A.
AU  - Travers,
AU  - J.
AU  - C.
AU  - Huffman,
AU  - J.
AU  - M.
AU  - Davis,
AU  - J.
AU  - L.
AU  - Mason,
AU  - R.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1089/aut.2020.0038
L1  - internal-pdf://0304621093/Bross.pdf
PY  - 2021
T2  - AUTISM IN ADULTHOOD
TI  - A Meta-Analysis of Video Modeling Interventions to Enhance Job Skills of Autistic Adolescents and Adults
UR  - https://www.liebertpub.com/doi/pdfplus/10.1089/aut.2020.0038
ER  -
TY  - JOUR
AB  - **Objectives**
This systematic review provides an overview of full economic evaluations of attention-deficit/hyperactivity disorder (ADHD) treatments, evaluates their outcomes, and highlights gaps in the literature. 

**Data Sources**
Electronic databases were searched for full economic evaluations of ADHD treatments for children, adolescents, or adults published in English or Dutch. 

**Results**
Twenty-nine studies met the inclusion criteria. Almost all studies that compared medication or psychosocial treatment to no treatment, placebo, or care as usual indicated that medication and psychosocial treatment were cost-effective compared to the control group. Stimulant treatment appeared to be cost-effective for the treatment of ADHD in children and adolescents. Only few studies focus on treatments in adults and psychosocial treatments and the number of studies with long time horizons and without industry funding is limited. 

**Conclusions**
Despite the rising interest in cost-effectiveness, this systematic review shows that more cost-effectiveness research of higher quality is warranted to aid in the optimal use of available treatments and resources for individuals with ADHD. Specifically, more studies should focus on treatments in adults and psychosocial treatments, and more studies with long time horizons and without industry funding are warranted. Nevertheless, we can conclude that treating ADHD is generally cost-effective compared to no treatment. PROSPERO: CRD42017060074. Available from: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=60074.
AN  - 34705525
AU  - Dijk,
AU  - H.
AU  - H.
AU  - Wessels,
AU  - L.
AU  - M.
AU  - Constanti,
AU  - M.
AU  - van
AU  - den
AU  - Hoofdakker,
AU  - B.
AU  - J.
AU  - Hoekstra,
AU  - P.
AU  - J.
AU  - Groenman,
AU  - A.
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1089/cap.2021.0068
L1  - internal-pdf://3305291732/Dijk-2021-Cost-Effectiveness and Cost Utility.pdf
PY  - 2021
SP  - 27
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Cost-Effectiveness and Cost Utility of Treatment of Attention-Deficit/Hyperactivity Disorder: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34705525
UR  - https://www.liebertpub.com/doi/10.1089/cap.2021.0068
UR  - https://www.liebertpub.com/doi/pdf/10.1089/cap.2021.0068?download=true
VL  - 27
ER  -
TY  - JOUR
AB  - **Background:**
Children, adolescents, and young adults with chronic conditions experience difficulties coping with disease-related stressors, comorbid mental health problems, and decreased quality of life. The COVID-19 pandemic has led to a global mental health crisis, and telemental health has necessarily displaced in-person care. However, it remains unknown whether such remote interventions are feasible or efficacious. We aimed to fill this research-practice gap.

**Objective:**
In this systematic review, we present a synthesis of studies examining the feasibility and efficacy of telemental health interventions for youth aged &le;25 years with chronic illnesses.

**Methods:**
PubMed, Embase, Web of Science, PsycInfo, and Cochrane Database of Systematic Reviews were searched from 2008 to 2020. We included experimental, quasiexperimental, and observational studies of telemental health interventions designed for children, adolescents, and young adults aged &le;25 years with chronic illnesses, in which feasibility or efficacy outcomes were measured. Only English-language publications in peer-reviewed journals were included. We excluded studies of interventions for caregivers or health care providers, mental health problems not in the context of a chronic illness, disease and medication management, and prevention programs for healthy individuals.

**Results:**
We screened 2154 unique study records and 109 relevant full-text articles. Twelve studies met the inclusion criteria, and they represented seven unique telemental health interventions. Five of the studies included feasibility outcomes and seven included efficacy outcomes. All but two studies were pilot studies with relatively small sample sizes. Most interventions were based on cognitive behavioral therapy and problem-solving therapy. The subset of studies examining intervention feasibility concluded that telemental health interventions were appropriate, acceptable, and satisfactory to patients and their parents. Technology did not create barriers in access to care. For the subset of efficacy studies, evidence in support of the efficacy of telemental health was mixed. Significant heterogeneity in treatment type, medical diagnoses, and outcomes precluded a meta-analysis.

**Conclusions:**
The state of the science for telemental health interventions designed for youth with chronic illnesses is in a nascent stage. Early evidence supports the feasibility of telehealth-based delivery of traditional in-person interventions. Few studies have assessed efficacy, and current findings are mixed. Future research should continue to evaluate whether telemental health may serve as a sustainable alternative to in-person care after the COVID pandemic.
AN  - 34448724
AU  - Lau,
AU  - N.
AU  - Colt,
AU  - S.
AU  - F.
AU  - Waldbaum,
AU  - S.
AU  - O&#039;Daffer,
AU  - A.
AU  - Fladeboe,
AU  - K.
AU  - Yi-Frazier,
AU  - J.
AU  - P.
AU  - McCauley,
AU  - E.
AU  - Rosenberg,
AU  - A.
AU  - R.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.2196/30098
L1  - internal-pdf://1471424169/Lau-2021-Telemental Health For Youth With Chro.pdf
PY  - 2021
SP  - e30098
T2  - JMIR Mental Health
TI  - Telemental Health For Youth With Chronic Illnesses: Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34448724
VL  - 8
ER  -
TY  - JOUR
AB  - Reports on remote psychotherapies for youth (e.g., technology-based treatment) suggest it is acceptable, feasible, and useful in overcoming logistical barriers to treatment. But how effective is remote care? 

To find out, PsycINFO and PubMed were searched from 1960 through 2020, supplemented by journal searches and reference trails, to identify randomized controlled trials of youth psychotherapy for anxiety (including obsessive-compulsive disorder and trauma), depression, attention-deficit/hyperactivity disorder (ADHD), or conduct problems, in which all therapeutic contact occurred remotely. Articles (N = 37) published from 1988 through 2020, reporting 43 treatment-control group comparisons, were identified. Robust variance estimation was used to account for effect size dependencies and to synthesize overall effects and test candidate moderators. 

Pooled effect size was .47 (95% confidence interval [CI: .26, .67], p &lt; .001) at posttreatment, .44 (95% CI [.12, .76], p &lt; .05) at follow-up-comparable to effects reported in meta-analyses of in-person youth psychotherapy. Effects were significantly (a) larger for remote psychotherapies supported by therapeutic provider contact (.64) than for those accessed by youths, with only logistical support (.22), (b) larger for treatments with phone contact (.65) than for those without (.25), (c) larger for treatment of anxiety (.62) and conduct problems (.78) than ADHD (-.03), and (d) smaller for therapies involving attention/working memory training (-.18) than for those without (.60). Among studies with therapeutic contact, effects were significantly larger when therapists facilitated skill-building (e.g., practicing exposures or problem solving [.68]) than when therapists did not (.18). 

These findings support the effectiveness of remote psychotherapies for youths, and they highlight moderators of treatment benefit that warrant attention in future research. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
AN  - 34807635
AU  - Venturo-Conerly,
AU  - K.
AU  - E.
AU  - Fitzpatrick,
AU  - O.
AU  - M.
AU  - Horn,
AU  - R.
AU  - L.
AU  - Ugueto,
AU  - A.
AU  - M.
AU  - Weisz,
AU  - J.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/amp0000816
L1  - internal-pdf://3382296965/Effectiveness of youth psychotherapy deli-2021.pdf
PY  - 2021
SP  - 22
T2  - American Psychologist
TI  - Effectiveness of youth psychotherapy delivered remotely: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34807635
VL  - 22
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
Young people (10-24 years old) with mental health concerns are increasingly presenting to hospital emergency departments (EDs). The purpose of this review was to identify the core components and outcomes of mental health interventions for young people that are initiated in the ED, such that they are delivered in the ED and/or by ED health workers. 

**METHODS**
Six electronic databases were systematically searched. Primary peer-reviewed qualitative or quantitative studies describing an ED-initiated mental health intervention for young people published between 2009 and 2020 were included. 

**RESULTS**
Nine studies met the inclusion criteria. The included studies demonstrated that compared with traditional ED care, ED-initiated mental health interventions lead to improved efficiency of care and decreased length of stay, and a core component of this care was its delivery by allied health practitioners with mental health expertise. The studies were limited by focusing on service efficiencies rather than patient outcomes. Further limitations were the exclusion of young people with complex mental health needs and/or comorbidities and not measuring long-term positive mental health outcomes, including representations and whether young people were connected with community health services. 

**CONCLUSIONS**
This systematic review demonstrated that ED-initiated mental health interventions result in improved service outcomes, but further innovation and robust evaluation are required. Future research should determine whether these interventions lead to better clinical outcomes for young people and staff to inform the development of best practice recommendations for ED-initiated mental health care for young people presenting to the ED.
AN  - 34620805
AU  - Walker,
AU  - N.
AU  - Medlow,
AU  - S.
AU  - Georges,
AU  - A.
AU  - Steinbeck,
AU  - K.
AU  - Ivers,
AU  - R.
AU  - Perry,
AU  - L.
AU  - Skinner,
AU  - S.
AU  - R.
AU  - Kang,
AU  - M.
AU  - Cullen,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/PEC.0000000000002551
L1  - internal-pdf://2510270204/Walker-2021-Emergency Department Initiated Men.pdf
PY  - 2021
SP  - 04
T2  - Pediatric Emergency Care
TI  - Emergency Department Initiated Mental Health Interventions for Young People: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34620805
VL  - 04
ER  -
TY  - JOUR
AB  - Token economy systems have been widely used as an evidence-based classroom management strategy to reinforce and improve prosocial responses. While token economies have been widely applied to educational settings, there have been mixed results regarding the effectiveness depending on the classroom type. 

To better understand the components contributing to the effectiveness, the researchers analyzed 24 token economy studies conducted in general and special education classrooms from kindergarten to fifth grade between 2000 and 2019. 

Eight token economy components and effect sizes were identified for each study and compared across different classroom types. The results showed that the token economy intervention yielded large effect sizes for both general and special education classroom types. There were differences in the usage of token components including backup reinforcer types, token production rate, and exchange production rate based on classroom types. 

Implications for future research and practice for educators and clinicians are discussed.
AN  - 34784784
AU  - Kim,
AU  - J.
AU  - Y.
AU  - Fienup,
AU  - D.
AU  - M.
AU  - Oh,
AU  - A.
AU  - E.
AU  - Wang,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/01454455211058077
L1  - internal-pdf://4205754071/Systematic Review and Meta-Analysis of To-2021.pdf
PY  - 2021
SP  - 1454455211058077
T2  - Behavior Modification
TI  - Systematic Review and Meta-Analysis of Token Economy Practices in K-5 Educational Settings, 2000 to 2019
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34784784
UR  - https://journals.sagepub.com/doi/10.1177/01454455211058077
UR  - https://journals.sagepub.com/doi/pdf/10.1177/01454455211058077
ER  -
TY  - JOUR
AB  - Har ikke doi: https://www.proquest.com/openview/32f392699f91c30aa624ab24f12d9bfd/1

Emotion recognition has been identified as critical in the development of social communication and interaction with individuals having autism spectrum disorder (ASD). However, little is known about the effects of the intervention and moderator factors with quantitative research. To carry out an analysis of effect size on the intervention emotion recognition of ASD, and to propose an optimal intervention plan, a meta-analysis was conducted across 22 randomized controlled trial studies involving 817 individuals with ASD, with the aim of analyzing the effectiveness of moderator variables. The findings of this study showed that the effect size of emotion recognition intervention for ASD reached a medium level (d = 0.69), and the effect size of the technology-based intervention (d = 0.90) was significantly greater than that of the non-technology-based intervention (d = 0.37). Though technology-based intervention may be a promising method on emotion recognition for ASD individuals, however, more well-controlled studies are needed.
AN  - WOS:000751661300008
AU  - Zhi,
AU  - W.
AU  - Cheong,
AU  - L.
AU  - S.
AU  - Jin,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - Har ikke DOI
L1  - internal-pdf://3990098075/Meta-Analysis of Emotion Recognition Inte-2021.pdf
PY  - 2021
SP  - 479-493
T2  - Education and Training in Autism and Developmental Disabilities
TI  - Meta-Analysis of Emotion Recognition Intervention Effects and Influencing Factors in Autism Spectrum
UR  - &lt;Go to ISI&gt;://WOS:000751661300008
VL  - 56
ER  -
TY  - JOUR
AB  - Global conflict in 2019 created record numbers of displaced children. These children have experienced multiple traumas and subsequently suffer high levels of mental health symptoms. Cognitive-behavioural therapy (CBT) is commonly used for post-traumatic stress disorder (PTSD), depression and anxiety, however the current evidence-base of CBT in child refugees is sparse, with mixed results. This study aimed to assess the effects of CBT on symptoms of PTSD, depression and anxiety in child refugees/AS. Ethics were reviewed and granted by the University of Manchester ethics committee. Medline, Embase, Cochrane, PsycINFO and CINAHL were systematically searched. Studies were included if CBT was delivered to refugee/AS children with pre and post-intervention measures of symptoms. Sixteen studies fulfilled criteria. In all studies, mental health symptom scores post-intervention had reduced, suggesting an improvement in mental health following CBT. This reduction was statistically significant in twelve studies (p &lt; 0.001-0.5), clinically significant in eight studies and maintained at follow-up periods. No adverse effects of CBT were identified. This is the first systematic review to focus solely on CBT in child refugee populations, with unanimously positive results. Its use is cautiously recommended, however the need for more methodologically rigorous studies in this population is highlighted.
AD  - Lawton, Katie. St Helens and Knowsley Teaching Hospitals NHS Trust, 474, Kings Road, Stretford, Manchester, M32 8QW, UK. Klawton3@doctors.org.uk.Spencer, Angela. University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
AN  - 33590440
AU  - Lawton,
AU  - K.
AU  - Spencer,
AU  - A.
DA  - Feb 15
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10903-021-01151-5
DP  - Ovid Technologies
J2  - J Immigr Minor Health
L1  - internal-pdf://3659642155/Lawton-2021-A Full Systematic Review on the Ef.pdf
LA  - English
N1  - Using Smart Source ParsingFebLawton, KatieSpencer, Angela
PY  - 2021
SP  - 15
T2  - Journal of Immigrant &amp; Minority Health
TI  - A Full Systematic Review on the Effects of Cognitive Behavioural Therapy for Mental Health Symptoms in Child Refugees
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33590440
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33590440&amp;id=doi:10.1007%2Fs10903-021-01151-5&amp;issn=1557-1912&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+Immigrant+%26+Minority+Health&amp;atitle=A+Full+Systematic+Review+on+the+Effects+of+Cognitive+Behavioural+Therapy+for+Mental+Health+Symptoms+in+Child+Refugees.&amp;aulast=Lawton&amp;pid=%3Cauthor%3ELawton+K%3C%2Fauthor%3E%3CAN%3E33590440%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s10903-021-01151-5.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - **Background** Human milk is the best enteral nutrition for preterm infants. However, human milk, given at standard recommended volumes, is not adequate to meet the protein, energy, and other nutrient requirements of preterm or low birth weight infants. One strategy that may be used to address the potential nutrient deficits is to give a higher volume of enteral feeds. High volume feeds may improve nutrient accretion and growth, and in turn may improve neurodevelopmental outcomes. However, there are concerns that high volume feeds may cause feed intolerance, necrotising enterocolitis, or complications related to fluid overload such as patent ductus arteriosus and chronic lung disease.This is an update of a review published in 2017.

**Objectives** To assess the effect on growth and safety of high versus standard volume enteral feeds in preterm or low birth weight infants. In infants who were fed fortified human milk or preterm formula, high and standard volume feeds were defined as &gt; 180 mL/kg/day and
AU  - Abiramalatha,
AU  - T.
AU  - Thomas,
AU  - N.
AU  - Thanigainathan,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD012413.pub3
L1  - internal-pdf://3305106782/Abiramalatha_et_al-2021-Cochrane_Database_of_S.pdf
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - High versus standard volume enteral feeds to promote growth in preterm or low birth weight infants
ER  -
TY  - JOUR
AB  - This review investigated whether randomised controlled trials attempting to improve sleep or prevent sleep problems in 0-5 year olds influenced nocturnal sleep duration, day-time naps, or 24-h sleep. 

Medline (Ovid), EMBASE, and CINAHL were searched from inception until 9 July 2020 and supplemented with hand searching. Search results were screened, eligible data were extracted, and risk of bias was assessed by at least two reviewers.

 Of 8571 publications considered, 32 trials which used a variety of subjective and objective sleep measurements were included in generic inverse variance random effects meta-analysis of nocturnal (n = 24), day-time (n = 14), and 24-h (n = 13) sleep duration. Overall, sleep interventions increased nocturnal sleep duration by a mean of 9 min (95% CI 4.1 to 13.8, I&lt;sup&gt;2&lt;/sup&gt;28%) per night when compared with no sleep intervention. Increases were predominantly seen in sleep-only, rather than multi-component interventions. Total 24-h sleep duration tended to increase by a similar amount (8.6 min (95% CI -2.7 to 19.8, I&lt;sup&gt;2&lt;/sup&gt; = 59%)), but this was mainly only seen in studies that assessed sleep using diaries. 

There was no evidence that interventions changed day-time sleep duration. Future studies should involve sleep-only rather than multi-component interventions, and use objective sleep measures (reviewregistry857).
AN  - 34029803
AU  - Fangupo,
AU  - L.
AU  - J.
AU  - Haszard,
AU  - J.
AU  - J.
AU  - Reynolds,
AU  - A.
AU  - N.
AU  - Lucas,
AU  - A.
AU  - W.
AU  - McIntosh,
AU  - D.
AU  - R.
AU  - Richards,
AU  - R.
AU  - Camp,
AU  - J.
AU  - Galland,
AU  - B.
AU  - C.
AU  - Smith,
AU  - C.
AU  - Taylor,
AU  - R.
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.smrv.2021.101498
L1  - internal-pdf://2773199272/Fangupo-2021.pdf
PY  - 2021
SP  - 101498
T2  - Sleep Medicine Reviews
TI  - Do sleep interventions change sleep duration in children aged 0-5 years? A systematic review and meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=34029803
UR  - https://www.sciencedirect.com/science/article/abs/pii/S1087079221000836?via%3Dihub
VL  - 59
ER  -
TY  - JOUR
AB  - Anxiety is the most common mental health problem that occurs with Autism Spectrum Disorder (ASD), and due to creating a more inclusive learning environment, children with ASD are placed in general education classrooms. Thus, addressing anxiety problems for children with ASD in school settings become critically important. This systematic review and meta-analysis investigated the current qualities of studies and the effects of school-based interventions for reducing anxiety in children with ASD. The study included six studies with a total of 165 participants. A random-effect meta-analysis yielded a moderate overall effect (g = - 0.58, 95% CI [- 0.96, - 0.20], z = - 3.01, p &lt; .05) with no significant heterogeneity, Q (5) = 7.31, p = 0.20. Findings of the systematic review indicated that school-based interventions for anxiety problems are still in the early stages, and studies showed significant issues with adaptations of current clinical-based interventions and anxiety measurements to use in school settings for children with ASD. Interpretation of these findings and implications are discussed.
AN  - WOS:000663273400001
AU  - Perihan,
AU  - C.
AU  - Bicer,
AU  - A.
AU  - Bocanegra,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12310-021-09461-7
L1  - internal-pdf://3919235630/Perihan-Assessment and Treatment of Anxiety in.pdf
PY  - 2021
SP  - 12
T2  - School Mental Health
TI  - Assessment and Treatment of Anxiety in Children with Autism Spectrum Disorder in School Settings: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000663273400001
UR  - https://link.springer.com/content/pdf/10.1007/s12310-021-09461-7.pdf
ER  -
TY  - JOUR
AB  - **Objective** Body image concerns and extreme weight control behaviors frequently develop in childhood indicating an important age group for the implementation of universal-selective prevention approaches. 

This systematic review aimed to evaluate the effect of universal-selective prevention interventions addressing disordered eating, body image concerns, and/or extreme weight control behaviors in children aged 6-12 years. Method Nine databases were searched up to April 2021. Studies were included if they delivered a universal-selective prevention intervention to children aged 6-12 years and reported outcomes relating to body image, disordered eating, or weight control behaviors. The review was conducted in line with the PRISMA Guidelines. 

**Results** A total of 42 articles describing 39 studies included in the review, with most (n = 24; 57%) classified as neutral quality. Thirty studies implemented an eating disorder specific universal-selective program and nine implemented lifestyle interventions plus content to address disordered eating risk factors. Meta-analysis (n = 16 studies) revealed an improvement in body image-related outcomes across all studies (standardized mean difference [SMD] 0.26 [95%CI 0.01, 0.51]); with a high level of heterogeneity (I2 = 89.9%; p &lt; .01). Meta-analysis according to gender revealed a general improvement in body image-related outcomes for girls (SMD 0.40 [95%CI 0.07, 0.73]), but not boys (SMD 0.23 [95%CI -0.24, 0.70]).

**Discussion** By investigating child, parental and teaching interventions and including outcomes such as weight control and disordered eating behaviors, a trend toward a reduction in eating disorder risk factors was observed, particularly body image-related outomes in girls. Future directions include embedded disordered eating prevention materials within existing lifestyle interventions and inclusion of more diverse samples.
AN  - WOS:000672122800001
AU  - Pursey,
AU  - K.
AU  - M.
AU  - Burrows,
AU  - T.
AU  - L.
AU  - Barker,
AU  - D.
AU  - Hart,
AU  - M.
AU  - Paxton,
AU  - S.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/eat.23571
L1  - internal-pdf://1198707869/Pursey-Disordered eating, body image concerns.pdf
PY  - 2021
SP  - 36
T2  - International Journal of Eating Disorders
TI  - Disordered eating, body image concerns, and weight control behaviors in primary school aged children: A systematic review and meta-analysis of universal-selective prevention interventions
UR  - &lt;Go to ISI&gt;://WOS:000672122800001
UR  - https://onlinelibrary.wiley.com/doi/10.1002/eat.23571
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/eat.23571?download=true
ER  -
TY  - JOUR
AB  - Translational research highlights the potential of novel &#039;memory consolidation/reconsolidation therapies&#039; to treat re-experiencing symptoms and post-traumatic stress disorder (PTSD). This systematic review and meta-analysis assessed the efficacy of so-called memory consolidation/reconsolidation therapies in randomised controlled trials (RCTs) for prevention and treatment of PTSD and symptoms of re-experiencing in children and adults (PROSPERO: CRD42020171167).

RCTs were identified and rated for risk of bias. Available data was pooled to calculate risk ratios (RR) for PTSD prevalence and standardised mean differences (SMD) for PTSD/re-experiencing severity. Twenty-five RCTs met inclusion criteria (16 prevention and nine treatment trials). The methodology of most studies had a significant risk of bias. We found a large effect of reconsolidation interventions in the treatment of PTSD (11 studies, n = 372, SMD: -1.42 (-2.25 to -0.58), and a smaller positive effect of consolidation interventions in the prevention of PTSD (12 studies, n = 2821, RR: 0.67 (0.50 to 0.90). 

Only three protocols (hydrocortisone for PTSD prevention, Reconsolidation of Traumatic Memories (RTM) for treatment of PTSD symptoms and cognitive task memory interference procedure with memory reactivation (MR) for intrusive memories) were superior to control. 

There is some emerging evidence of consolidation and reconsolidation therapies in the prevention and treatment of PTSD and intrusive memories specifically. Translational research should strictly adhere to protocols/procedures describing precise reconsolidation conditions (e.g. MR) to both increase the likelihood of positive findings and more confidently interpret negative findings of putative reconsolidation agents.
AN  - 34480016
AU  - Astill
AU  - Wright,
AU  - L.
AU  - Horstmann,
AU  - L.
AU  - Holmes,
AU  - E.
AU  - A.
AU  - Bisson,
AU  - J.
AU  - I.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1038/s41398-021-01570-w
L1  - internal-pdf://3838776925/Astill Wright-2021-Consolidation_reconsolidati.pdf
PY  - 2021
SP  - 453
T2  - Transl Psychiatry Psychiatry
TI  - Consolidation/reconsolidation therapies for the prevention and treatment of PTSD and re-experiencing: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34480016
UR  - https://www.nature.com/articles/s41398-021-01570-w.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Background** The efficacy of technology-delivered cognitive-behavioral therapy (tCBT) for pediatric anxiety disorders (ADs) is uncertain as no meta-analysis has examined outcomes in trials that used structured diagnostic assessments at pre- and posttreatment. 

**Methods** We carried out a systematic review and meta-analysis of randomized controlled trials (RCTs) of tCBT for pediatric ADs that included participants &lt;18 years of age with a confirmed primary AD according to a structured diagnostic interview. Nine studies with 711 participants were included. 

**Results** tCBT outperformed control conditions for remission for primary AD (37.9% vs. 10.2%; k = 9; OR = 4.73; p I-2 = 0%; moderate certainty), remission for all ADs (19.5% vs. 5.3%; k = 8; OR = 3.32; p I-2 = 0%; moderate certainty), clinician-rated functioning (k = 7; MD = -4.38; p I-2 = 56.9%; low certainty), and caregiver-reported anxiety (k = 7; SMD = 0.27; p = .02; I-2 = 41.4%; low certainty), but not for youth-reported anxiety (k = 9; SMD = 0.13; p = .12; I-2 = 0%; low certainty). More severe pretreatment anxiety, a lower proportion of completed sessions, no face-to-face sessions, media recruitment, and a larger proportion of females were associated with lower remission rates for primary AD. 

**Conclusions** tCBT has a moderate effect on remission for pediatric ADs and clinician-rated functioning, a small effect on caregiver-reported anxiety, and no statistically significant effect on youth-reported anxiety. The certainty of these estimates is low to moderate. Remission rates vary substantially across trials and several factors that may influence remission were identified. Future research should examine for whom tCBT is most appropriate and what care to offer the large proportion that does not remit. Future RCTs should consider contrasting tCBT with partial tCBT (e.g., including therapist-led exposure) and/or face-to-face CBT.
AN  - WOS:000670441900001
AU  - Cervin,
AU  - M.
AU  - Lundgren,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13485
L1  - internal-pdf://2708958708/Cervin-Technology-delivered cognitive-behavior.pdf
PY  - 2021
SP  - 12
T2  - Journal of Child Psychology and Psychiatry
TI  - Technology-delivered cognitive-behavioral therapy for pediatric anxiety disorders: a meta-analysis of remission, posttreatment anxiety, and functioning
UR  - &lt;Go to ISI&gt;://WOS:000670441900001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.13485?download=true
ER  -
TY  - JOUR
AB  - This is the first systematic review of the school outcome literature for behavior interventions used with middle school students exhibiting disruptive behaviors. A total of 51 investigations (published between 2000 and 2020) including 6,498 students and 264 implementers were coded on four dimensions (i.e., sample, interventions, methodology, and outcomes). This review examined intervention effects on implementer and student outcomes, yielding small to large positive effects. Strengths of the reviewed studies included the specification of student characteristics, operationalization of implementers&#039; professional development, and assessment of intervention fidelity. Most studies used single-case designs or randomized controlled trial experimental designs to evaluate the effectiveness of the interventions. Weaknesses included an absence of student diagnostic information; lack of data on implementers, attrition, and follow-up; and inadequate use of parent involvement. School practitioners should be mindful of developmental challenges and consider targets and barriers to implementation. Additional large-scale, rigorous experimental designs are warranted. Supplemental data for this article is available online at . 

**IMPACT STATEMENT **This is the first study to review the school outcome literature for behavior interventions and supports used with middle school students with or at risk of disruptive behavior disorders (DBDs). Research-based behavior interventions are essential to ameliorating the negative outcomes associated with student disruptive behavior in middle school, which is a significant transitional period.
AN  - WOS:000648132000001
AU  - Alperin,
AU  - A.
AU  - Reddy,
AU  - L.
AU  - A.
AU  - Glover,
AU  - T.
AU  - A.
AU  - Bronstein,
AU  - B.
AU  - Wiggs,
AU  - N.
AU  - B.
AU  - Dudek,
AU  - C.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/2372966x.2021.1883996
L1  - internal-pdf://0664029619/Alperin-School-Based Interventions for Middle.pdf
PY  - 2021
SP  - 26
T2  - School Psychology Review
TI  - School-Based Interventions for Middle School Students With Disruptive Behaviors: A Systematic Review of Components and Methodology
UR  - &lt;Go to ISI&gt;://WOS:000648132000001
UR  - https://www.tandfonline.com/doi/full/10.1080/2372966X.2021.1883996
UR  - https://www.tandfonline.com/doi/pdf/10.1080/2372966X.2021.1883996?needAccess=true
ER  -
TY  - JOUR
AB  - **BACKGROUND**: There is&nbsp;great global variation in the sleeping arrangements for healthy newborn infants. Bed sharing&nbsp;is a type of sleeping practice in which the sleeping surface (e.g. bed, couch or armchair, or some other sleeping surface) is shared between the infant and another person. The possible physiological benefits include better oxygen and cardiopulmonary stability, fewer crying episodes, less risk of hypothermia, and a longer duration of breastfeeding. On the other hand, the most important harmful effect of bed sharing is that it may increase the risk of sudden infant death syndrome (SIDS). Studies have found conflicting evidence regarding the safety and efficacy of bed sharing during infancy. 

**OBJECTIVES**: To evaluate the efficacy and safety of bed sharing, started during the neonatal period, on breastfeeding status (exclusive and total duration of breastfeeding), incidence of SIDS, rates of hypothermia, neonatal and infant mortality, and long-term neurodevelopmental outcomes. 

**SEARCH METHODS**: We used the standard search strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL 2020, Issue 7) in the Cochrane Library; MEDLINE via PubMed (1966 to 23 July 2020), CINAHL (1982 to 23 July 2020), and LILACS (1980 to&nbsp;23 July 2020). We also searched clinical trials databases, and the reference lists of retrieved articles, for randomised controlled trials (RCTs) and quasi-RCTS. 

**SELECTION CRITERIA**: We planned to include RCTs or quasi-RCTs (including cluster-randomised trials) that included term neonates initiated on bed sharing&nbsp;within 24 hours of birth (and continuing to bed share with the mother in the first four weeks of life, followed by a variable time period thereafter), and compared them to a &#039;no bed sharing&#039; group. DATA 

**COLLECTION AND ANALYSIS**: We used standard methodological procedures as recommended by Cochrane. We planned to use the GRADE approach to assess the certainty of evidence. 

**MAIN RESULTS**: Our search strategy yielded 6231 records. After removal of duplicate records, we screened 2745 records by title and abstract. We excluded 2739 records that did not match our inclusion criteria. We obtained six full-text studies for assessment. These six studies did not meet the eligibility criteria and were excluded. 

**AUTHORS&#039; CONCLUSIONS**: We did not find any studies that met our inclusion criteria. There is a need for RCTs on bed sharing in healthy term neonates that directly assess efficacy (i.e. studies in a controlled setting, like hospital) or effectiveness (i.e. studies conducted in community or home settings) and safety. Future studies should assess outcomes such as&nbsp;breastfeeding status and risk of SIDS. They should also&nbsp;include neonates from&nbsp;high-income countries and low- and middle-income countries, especially those countries where&nbsp;bed sharing is more prevalent because of cultural practices (e.g. Asian countries).
AD  - Department of Pediatrics, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, India.Newborn Health Knowledge Centre, WHO Collaborating Centre for Training and Research in Newborn Care, Department of Pediatrics, All India Institute of Medical Sciences, Delhi, India.
AN  - 33831222
AU  - Das,
AU  - R.
AU  - R.
AU  - Sankar,
AU  - M.
AU  - J.
AU  - Agarwal,
AU  - R.
DA  - Apr 8
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD012866.pub2
DP  - NLM
J2  - The Cochrane database of systematic reviews
KW  - *Beds
KW  - Humans
KW  - Infant
KW  - Infant Care/*methods
KW  - Infant, Newborn
KW  - *Term Birth
LA  - eng
N1  - 1469-493xDas, Rashmi RSankar, Mari JeevaAgarwal, RameshJournal ArticleResearch Support, Non-U.S. Gov&#039;tSystematic ReviewCochrane Database Syst Rev. 2021 Apr 8;4(4):CD012866. doi: 10.1002/14651858.CD012866.pub2.
PY  - 2021
SP  - Cd012866
T2  - Cochrane Database Syst Rev
TI  - Bed sharing versus no bed sharing for healthy term neonates
VL  - 4
ER  -
TY  - JOUR
AB  - In this review, we systematically explored research on the use of non-directive therapies with adolescents (aged 11-18 years) with autism spectrum disorder (ASD). 

N = 12 studies were eligible for inclusion. The findings suggested four therapeutic components which were consistently present across all non-directive interventions and held similarities with play therapy principles: (a) collaboration between adolescent and therapist; (b) adolescent-led discussions; (c) reflection and reframing; and (d) encouragement and acceptance of the adolescent as they were. 

Therapeutic outcomes improved when the therapists had an understanding of ASD in order to tailor the intervention to the individual. Future primary research investigating the applicability of play therapy principles and limitations is discussed.
AN  - WOS:000733379200001
AU  - Casper,
AU  - R.
AU  - Shloim,
AU  - N.
AU  - Hebron,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/capr.12504
L1  - internal-pdf://0318902136/Couns and Psychother Res - 2021 - Casper - Use.pdf
PY  - 2021
SP  - 13
T2  - Counselling &amp; Psychotherapy Research
TI  - Use of non-directive therapy for adolescents with autism spectrum disorder: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000733379200001
UR  - https://onlinelibrary.wiley.com/doi/10.1002/capr.12504
ER  -
TY  - JOUR
AB  - BAKGRUNN
Formålet med denne kunnskapsoppsummering er å undersøke om Kjærlighet og Grenser (v. 2019) er virksomt når det tilbys i vanlig praksis i Norge. Artikkelen bygger på en tidligere beskrivelse av det samme tiltaket i Ungsinn (Bjørknes, 2011; Bjørknes &amp; Koposov, 2018). Tiltakseier har oppdatert programmet noe siden da og denne artikkelen tar utgangspunkt i den oppdaterte versjonen med et oppdatert litteratursøk. Kjærlighet og Grenser er ment å være et rusforebyggende program rettet mot ungdom i alderen 12&ndash;13 år og deres foreldre. Kompetansesenter rus &ndash; region sør (KoRus Sør) har det nasjonale ansvaret for å utvikle og gi opplæring i programmet. Programmet er opprinnelig utviklet i USA (Iowa Strengthening Families Program), videreutviklet i Sverige (ParentSteps, Step-by-Step) og implementert i Norge fra 2004.

METODE
Det ble gjort litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Søket resulterte i to svenske effektstudier som ble inkludert.

RESULTATER
Resultatene omfatter en beskrivelse av programmet samt en oppsummering av effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Programmet har tilfredsstillende systemer for å sikre implementeringskvalitet. Det foreligger to studier fra Sverige som undersøker effekten av tiltaket. Begge studiene benytter randomiserte design med kontrollgrupper, målinger ved oppstart og senere oppfølging. Studiene er av god forskningsmetodisk kvalitet. Det er ikke funnet signifikante positive effekter på relevante utfallsmål, slik som unges rus- eller atferdsproblemer. I tillegg er ikke internasjonale kunnskapsoppsummeringer samstemt i sine konklusjoner om programmet er virksomt.

KONKLUSJON
Basert på Ungsinn sine kriterier klassifiseres Kjærlighet og Grenser på evidensnivå 0 &ndash; uvirksomt tiltak. Studiene som er gjennomført er av god forskningsmetodisk kvalitet og viser at
tiltaket ikke har effekt. Dette understøttes av at internasjonale kunnskapsoppsummeringer ikke er samstemt i sine konklusjoner om programmet er virksomt.
AU  - Bjørknes,
AU  - R.,
AU  - Koposov,
AU  - R.,
AU  - Eng,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2021
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Kjærlighet og Grenser (3. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/kjaerlighet-og-grenser-3-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - BACKGROUND: We aimed to evaluate the effect of music-based intervention on the aggressive behavior in children and adolescents, and made a comparison of music medicine and music therapy.

METHODS: We searched PubMed (MEDLINE), Ovid-Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) to identify relevant studies. Standardized mean differences (SMDs) were estimated with random-effect model.

RESULTS: We included 10 studies and found a significant decrease of aggressive behavior (SMD = -0.99; 95% CI = -1.42 to -0.56) and a significant increase of self-control (SMD = 0.56; 95% CI: 0.19 to 0.93) in the music-based intervention group compared with the control group. The aggressive behavior was significantly decreased in the music therapy group compared with the control group (SMD = -1.79; 95% CI = -3.23 to -0.35); while, no difference was observed between music medicine group and control group. Sub-group analyses exhibited a more efficacious in reducing aggressive behavior in the children received &gt;=2 sessions per week, the children with a mean age &gt; 10 years, the children whose behavior were reported by teachers, and the children with aggressive behavior before intervention. Sensitivity analyses yielded similar results.

CONCLUSION: Music-based intervention seemed to be more efficacious for reducing aggression and increasing self-control in children and adolescents, especially music therapy.
AD  - Ye, Peijie. Bengbu Medical University.Huang, Zhaohui. Anhui Provincial Center for Women and Child Health, Hefei, Anhui, China.Zhou, Huan. Bengbu Medical University.Zhou, Huan. National Drug Clinical Trial Institution, the First Affiliated Hospital of Bengbu Medical University, Bengbu.Tang, Qishou. Bengbu Medical University.
AN  - 33530185
AU  - Ye,
AU  - P.
AU  - Huang,
AU  - Z.
AU  - Zhou,
AU  - H.
AU  - Tang,
AU  - Q.
DA  - Februar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/MD.0000000000023894
DP  - Ovid Technologies
J2  - Medicine (Baltimore)
KW  - Adolescent
KW  - Adolescent Behavior/px [Psychology]
KW  - *Adolescent Behavior
KW  - *Aggression
KW  - Child
KW  - Child Behavior Disorders/px [Psychology]
KW  - *Child Behavior Disorders/th [Therapy]
KW  - Humans
KW  - *Music Therapy
KW  - Self-Control
L1  - internal-pdf://0620936881/Ye-2021-Music-based intervention to reduce agg.pdf
LA  - English
M3  - Meta-AnalysisSystematic Review
N1  - Ye, PeijieHuang, ZhaohuiZhou, HuanTang, Qishou
PY  - 2021
SP  - e23894
T2  - Medicine
TI  - Music-based intervention to reduce aggressive behavior in children and adolescents: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=33530185
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33530185&amp;id=doi:10.1097%2FMD.0000000000023894&amp;issn=0025-7974&amp;isbn=&amp;volume=100&amp;issue=4&amp;spage=e23894&amp;pages=e23894&amp;date=2021&amp;title=Medicine&amp;atitle=Music-based+intervention+to+reduce+aggressive+behavior+in+children+and+adolescents%3A+A+meta-analysis.&amp;aulast=Ye&amp;pid=%3Cauthor%3EYe+P%3C%2Fauthor%3E%3CAN%3E33530185%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850739/pdf/medi-100-e23894.pdf
VL  - 100
ER  -
TY  - JOUR
AB  - Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting approxi-mately 2% of children in the United States. Growing evidence suggests that immune dysregulation is associated with ASD. One immunomodulatory treatment that has been studied in ASD is intravenous immunoglobulins (IVIG). 

This systematic review and meta-analysis examined the studies which assessed immunoglobulin G (IgG) concentrations and the therapeutic use of IVIG for individuals with ASD. Twelve studies that examined IgG levels suggested abnormalities in total IgG and IgG 4 subclass concentrations, with concentrations in these IgGs related to aberrant behavior and social impairments, respectively. Meta-analysis supported possible subsets of children with ASD with low total IgG and elevated IgG 4 subclass but also found significant variability among studies. 

A total of 27 publications reported treating individuals with ASD using IVIG, including four prospective, controlled studies (one was a double-blind, placebo-controlled study); six prospective, uncontrolled studies; 2 retrospective, controlled studies; and 15 retrospective, uncontrolled studies. In some studies, clinical improvements were observed in communication, irritability, hyperactivity, cogni-tion, attention, social interaction, eye contact, echolalia, speech, response to commands, drowsiness, decreased activity and in some cases, the complete resolution of ASD symptoms. Several studies reported some loss of these improvements when IVIG was stopped. Meta-analysis combining the aberrant behavior checklist outcome from two studies demonstrated that IVIG treatment was signif-icantly associated with improvements in total aberrant behavior and irritability (with large effect sizes), and hyperactivity and social withdrawal (with medium effect sizes). Several studies reported improvements in pro-inflammatory cytokines (including TNF-alpha). Six studies reported improvements in seizures with IVIG (including patients with refractory seizures), with one study reporting a worsening of seizures when IVIG was stopped. Other studies demonstrated improvements in recurrent infections, appetite, weight gain, neuropathy, dysautonomia, and gastrointestinal symptoms. Adverse events were generally limited but included headaches, vomiting, worsening behaviors, anxiety, fever, nausea, fatigue, and rash. Many studies were limited by the lack of standardized objective outcome measures. 

IVIG is a promising and potentially effective treatment for symptoms in individuals with ASD; further research is needed to provide solid evidence of efficacy and determine the subset of children with ASD who may best respond to this treatment as well as to investigate biomarkers which might help identify responsive candidates. Copyright &copy; 2021 by the authors. Licensee MDPI, Basel, Switzerland.
AN  - 2007469299
AU  - Rossignol,
AU  - D.
AU  - A.
AU  - Frye,
AU  - R.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/jpm11060488
L1  - internal-pdf://4077050021/Rossignol-2021-A systematic review and meta-an.pdf
PY  - 2021
T2  - Journal of Personalized Medicine
TI  - A systematic review and meta-analysis of immunoglobulin g abnormalities and the therapeutic use of intravenous immunoglobulins (Ivig) in autism spectrum disorder
UR  - https://www.mdpi.com/2075-4426/11/6/488/pdf
UR  - https://res.mdpi.com/d_attachment/jpm/jpm-11-00488/article_deploy/jpm-11-00488.pdf
VL  - 11 (6) (no pagination)
ER  -
TY  - JOUR
AB  - **Objective**: To assess the effectiveness of noninstitutional psychosocial interventions in preventing recidivism among criminal adolescents. 

**Method**: We performed a systematic review and meta-analysis of randomized and nonrandomized controlled trials assessing the impact on recidivism among juveniles aged 12-17. The included studies had a low to medium risk of bias and were published between 2000 and 2019. Standardized mean differences or risk differences were calculated. 

**Results**: We included 35 (20 randomized, 15 nonrandomized) studies evaluating 17 unique, noninstitutional psychosocial interventions. A meta-analysis found no significant reductions in recidivism for studied interventions compared to control conditions. Although single studies suggested some positive effects, the evidence provided by these studies was found to have very low certainty. Post hoc analyses indicated that studies including a low-intensity control condition might have stronger relative intervention effects compared to studies with medium or high-intensity control conditions. 

**Conclusion**: This systematic review did not find any one noninstitutional psychosocial intervention to be more effective than control treatments in reducing future criminality among juvenile offenders aged 12-17. We discuss the implications of the present findings for social work and child and adolescent psychiatry practices. (PsycInfo Database Record (c) 2021 APA, all rights reserved) Impact Statement &lt;strong xmlns:lang=&quot;en&quot;&gt;What is the public health significance of this article?-This systematic review and meta-analysis did not find any one noninstitutional psychosocial intervention to be more effective than control treatments in reducing future criminality among juvenile offenders aged 12-17. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-62983-003
AU  - Olsson,
AU  - Tina
AU  - M.
AU  - Langstrom,
AU  - Niklas
AU  - Skoog,
AU  - Therese
AU  - Andree
AU  - Lofholm,
AU  - Cecilia
AU  - Leander,
AU  - Lina
AU  - Brolund,
AU  - Agneta
AU  - Ringborg,
AU  - Anna
AU  - Nykanen,
AU  - Pia
AU  - Syversson,
AU  - Anneth
AU  - Sundell,
AU  - Knut
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/ccp0000652
L1  - internal-pdf://3130508557/Olsson-2021-Systematic review and meta-analysi.pdf
PY  - 2021
SP  - 514-527
T2  - Journal of Consulting and Clinical Psychology
TI  - Systematic review and meta-analysis of noninstitutional psychosocial interventions to prevent juvenile criminal recidivism
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-62983-003
VL  - 89
ER  -
TY  - JOUR
AB  - Children with parents suffering from a psychiatric disorder are at higher risk for developing a mental disorder themselves. This systematic review and meta-analysis of randomized controlled trials aims to evaluate the efficacy of psychosocial interventions to prevent negative mental health outcomes in the offspring of parents with mental illness. 

Eight electronic databases, grey literature and a journal hand-search identified 14 095 randomized controlled trials with no backward limit to June 2021. Outcomes in children included incidence of mental disorders (same or different from parental ones) and internalizing and externalizing symptoms at post-test, short-term and long-term follow-up. Relative risks and standardized mean differences (SMD) for symptom severity were generated using random-effect meta-analyses. 

Twenty trials were selected (pooled n = 2689 children). The main therapeutic approaches found were cognitive-behavioural therapy and psychoeducation. A significant effect of interventions on the incidence of mental disorders in children was found with a risk reduction of almost 50% [combined relative risk = 0.53, 95% confidence interval (CI) 0.34-0.84]. 

Interventions also had a small but significant effect on internalizing symptoms at post-test (SMD = -0.25, 95% CI -0.37 to -0.14) and short-term follow-up (-0.20, 95% CI -0.37 to -0.03). For externalizing symptoms, a decreasing slope was observed at post-test follow-up, without reaching the significance level (-0.11, 95% CI -0.27 to 0.04). 

Preventive interventions targeting the offspring of parents with mental disorders showed not only a significant reduction of the incidence of mental illness in children, but also a diminution of internalizing symptoms in the year following the intervention.
AN  - 34435556
AU  - Lannes,
AU  - A.
AU  - Bui,
AU  - E.
AU  - Arnaud,
AU  - C.
AU  - Raynaud,
AU  - J.
AU  - P.
AU  - Revet,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1017/S0033291721003366
L1  - internal-pdf://2960795102/Lannes-2021-Preventive interventions in offspr.pdf
PY  - 2021
SP  - 1-16
T2  - Psychological Medicine
TI  - Preventive interventions in offspring of parents with mental illness: a systematic review and meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34435556
UR  - https://www.cambridge.org/core/journals/psychological-medicine/article/abs/preventive-interventions-in-offspring-of-parents-with-mental-illness-a-systematic-review-and-metaanalysis-of-randomized-controlled-trials/24D36882C376B505170BD1A0DABB0101
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/24D36882C376B505170BD1A0DABB0101/S0033291721003366a.pdf/div-class-title-preventive-interventions-in-offspring-of-parents-with-mental-illness-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials-div.pdf
ER  -
TY  - JOUR
AB  - **Objective**: To investigate the effect of iodine supplementation during gestation on the neurocognitive development of children in areas where iodine deficiency is common. 

**Methods**: Based on the PRISMA methodology, we conducted the search for articles in the PubMed, LILACS and Scopus databases, between March and April 2020, without limitation of dates. We used descriptors in English, Portuguese, and Spanish, without filters. Four clinical trials and four cohort articles were included in the review. 

**Results**: The maximum supplementation was 300 mug of potassium iodide per day. The Bayley scale and Children&#039;s Communication Checklist-Short were used to assess neurodevelopment in children. There was no significant improvement in the children&#039;s mental development index and behavioural development index in the supplemented group; however, the psychomotor development index (PDI) showed improvement in the poorer gross motor skills. We found differences in the response time to sound in the supplemented group living in mild deficiency areas. 

**Conclusion**: Daily supplementation with iodine can improve poor psychomotor development of children living in mild to moderate iodine deficiency areas. Thus, it is necessary to perform further studies to assess the effect of supplementation on neurodevelopment before, during and after gestation in mild to moderate iodine deficiency areas.
AN  - 34191411
AU  - Machamba,
AU  - A.
AU  - A.
AU  - L.
AU  - Azevedo,
AU  - F.
AU  - M.
AU  - Fracalossi,
AU  - K.
AU  - O.
AU  - do,
AU  - C.
AU  - C.
AU  - Franceschini
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.20945/2359-3997000000376
L1  - internal-pdf://4076322609/Machamba-2021-Effect of iodine supplementation.pdf
PY  - 2021
SP  - 352-367
T2  - Archives of Endocrinology &amp; Metabolism
TI  - Effect of iodine supplementation in pregnancy on neurocognitive development on offspring in iodine deficiency areas: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34191411
UR  - https://www.scielo.br/j/aem/a/5YLyvPgSgXryRYjB43RnLFD/?format=pdf&amp;lang=en
VL  - 65
ER  -
TY  - JOUR
AB  - **Objective**
Over the last 10 years, online interventions to improve mental health have increased significantly. This study&#039;s primary objective was to determine the effectiveness of online interventions in improving the mental health of pediatric, adolescent, and young adult (PAYA) cancer survivors. The secondary objective was to identify the independent variables associated with online intervention efficacy for mental health improvement. 

**Method(s)**
On June 25-30, 2021, we searched the Medline, PsycINFO, EMBASE, and Cochrane databases for eligible English language publications that reported randomized controlled trials of online interventions aimed at improving mental health among PAYA cancer survivors. The results were analyzed using a systematic review and a three-level meta-analysis. 

**Result(s)**
Thirteen studies met the inclusion criteria. In six (42%) studies, the intervention focused on physical activity enhancement, while ten (77%) studies used self-directed interventions. Online interventions were more efficacious, compared to control conditions, in improving sleep g = 0.35 (95% CI 0.04-0.66) and psychological well-being g = 0.32 (95% CI 0.09-0.56), but not for reducing the symptoms of depression g = 0.17 (95% CI -0.13 to 0.47), anxiety g = 0.05 (95% CI -0.15 to 0.25), and pain g = 0.13 (95% CI -0.13 to 0.39). 

**Conclusion(s)**
Online interventions were generally effective in improving mental health in PAYA cancer survivors, although negative results were found in some critical outcomes. More high-quality evidence is needed for definite conclusions to be drawn. The study protocol was registered in PROSPERO (CRD42021266276). Copyright &copy; 2021 Chandeying and Thongseiratch.
AN  - 636810693
AU  - Chandeying,
AU  - N.
AU  - Thongseiratch,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2021.784615
L1  - internal-pdf://3813250248/Online Interventions to Improve Mental He-2021.pdf
PY  - 2021
T2  - Frontiers in Psychiatry
TI  - Online Interventions to Improve Mental Health of Pediatric, Adolescent, and Young Adult Cancer Survivors: A Systematic Review and Meta-Analysis
UR  - http://www.frontiersin.org/Psychiatry
VL  - 12 (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
The effect of interventions based on the creative arts for children and adolescents exposed to traumatic events was estimated for measures of post-traumatic stress disorder (PTSD) and other psychological symptoms. 

**METHOD**
Using a pre-registered protocol, relevant journal articles were identified through searches of: PsycInfo; Psychology and Behavioural Sciences Collection; CINAHL and PsycArticles. Data were pooled using a random effects model, and effect estimates were reported as Hedges&#039; g. 

**RESULTS**
Pooled effect estimates indicated that arts-based interventions significantly reduced PTSD symptom scores compared to pre-intervention (15 studies, g = -.67, p &lt; .001) and a control group (7 studies, g = -.50, p &lt; .001). Significant reductions were also found for measures of negative mood, but results were mixed for externalizing problems and anxiety. 

**CONCLUSIONS**
 Despite variations in study quality, intervention approaches and types of trauma experience, the results tentatively suggest that creative arts-based interventions may be effective in reducing symptoms of trauma and negative mood.
AN  - 34969356
AU  - Morison,
AU  - L.
AU  - Simonds,
AU  - L.
AU  - Stewart,
AU  - S.
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/17533015.2021.2009529
L1  - internal-pdf://2365432608/Effectiveness of creative arts-based inte-2021.pdf
PY  - 2021
SP  - 1-26
T2  - Arts &amp; Health
TI  - Effectiveness of creative arts-based interventions for treating children and adolescents exposed to traumatic events: a systematic review of the quantitative evidence and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34969356
UR  - https://www.tandfonline.com/doi/full/10.1080/17533015.2021.2009529
ER  -
TY  - JOUR
AB  - In school, shyness is associated with psychosocial difficulties and has negative impacts on children&#039;s academic performance and wellbeing. Even though there are different strategies and interventions to help children deal with shyness, there is currently no comprehensive systematic review of available interventions. 

This systematic review and meta-analysis aim to identify interventions for shy children and to evaluate the effectiveness in reducing psychosocial difficulties and other impacts. The methodology and reporting were guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement and checklist. 

A total of 4,864 studies were identified and 25 of these met the inclusion criteria. These studies employed interventions that were directed at school-aged children between six and twelve years of age and described both pre- and post-intervention measurement in target populations of at least five children. Most studies included an intervention undertaken in a school setting. The meta-analysis revealed interventions showing a large effect in reducing negative consequences of shyness, which is consistent with extant literature regarding shyness in school, suggesting school-age as an ideal developmental stage to target shyness. None of the interventions were delivered in a classroom setting, limiting the ability to make comparisons between in-class interventions and those delivered outside the classroom, but highlighting the effectiveness of interventions outside the classroom. The interventions were often conducted in group sessions, based at the school, and involved activities such as play, modelling and reinforcement and clinical methods such as social skills training, psychoeducation, and exposure. Traditionally, such methods have been confined to a clinic setting. 

The results of the current study show that, when such methods are used in a school-based setting and involve peers, the results can be effective in reducing negative effects of shyness. This is consistent with recommendations that interventions be age-appropriate, consider social development and utilise wide, school-based programs that address all students.
AN  - 34242303
AU  - Cordier,
AU  - R.
AU  - Speyer,
AU  - R.
AU  - Mahoney,
AU  - N.
AU  - Arnesen,
AU  - A.
AU  - Mjelve,
AU  - L.
AU  - H.
AU  - Nyborg,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0254117
L1  - internal-pdf://0785348489/Cordier-2021-Effects of interventions for soci.pdf
PY  - 2021
SP  - e0254117
T2  - PLoS ONE [Electronic Resource]
TI  - Effects of interventions for social anxiety and shyness in school-aged children: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34242303
UR  - https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0254117/1/pone.0254117.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&amp;X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210825%2Fauto%2Fstorage%2Fgoog4_request&amp;X-Goog-Date=20210825T075642Z&amp;X-Goog-Expires=86400&amp;X-Goog-SignedHeaders=host&amp;X-Goog-Signature=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
VL  - 16
ER  -
TY  - JOUR
AB  - Introduction: 
Sample enrichment is a key factor in contemporary early-detection strategies aimed at the identification of help-seekers at increased risk of imminent transition to psychosis. We undertook a meta-analytic investigation to ascertain the role of sample enrichment in the recently highlighted negative prognostic effect of baseline antipsychotic (AP) exposure in clinical high-risk (CHR-P) of psychosis individuals. 

Method(s): 
Systematic review and meta-analysis of all published studies on CHR-P were identified according to a validated diagnostic procedure. The outcome was the proportion of transition to psychosis, which was calculated according to the Freeman-Tukey double arcsine transformation. 

Result(s): 
Thirty-three eligible studies were identified, including 16 samples with details on AP exposure at baseline and 17 samples with baseline AP exposure as exclusion criterion for enrollment. Those with baseline exposure to AP (n = 395) had higher transition rates (29.9%; 95% CI: 25.1%-34.8%) than those without baseline exposure to AP in the same study (n = 1289; 17.2%; 15.1%-19.4%) and those coming from samples that did not include people who were exposed to AP at baseline (n = 2073; 16.2%; 14.6%-17.8%; P &lt;. 05 in both the fixed-effects and the random-effects models). Heterogeneity within studies was substantial, with values above 75% in all comparisons. 

Conclusion(s): 
Sample enrichment is not a plausible explanation for the higher risk of transition to psychosis of CHR-P individuals who were already exposed to AP at the enrollment in specialized early-detection programs. Baseline exposure to AP at CHR-P assessment is a major index of enhanced, imminent risk of psychosis. Copyright &copy; 2021 The Author(s) 2021. Published by Oxford University Press on behalf of CINP.
AN  - 2015068758
AU  - Raballo,
AU  - A.
AU  - Poletti,
AU  - M.
AU  - Preti,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/ijnp/pyab030
L1  - internal-pdf://1254165089/Negative Prognostic Effect of Baseline An-2021.pdf
PY  - 2021
SP  - 710-720
T2  - International Journal of Neuropsychopharmacology
TI  - Negative Prognostic Effect of Baseline Antipsychotic Exposure in Clinical High Risk for Psychosis (CHR-P): Is Pre-Test Risk Enrichment the Hidden Culprit?
UR  - http://ijnp.oxfordjournals.org/
UR  - https://watermark.silverchair.com/pyab030.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAsEwggK9BgkqhkiG9w0BBwagggKuMIICqgIBADCCAqMGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMuN1fzaM6VbMUS6YJAgEQgIICdJhe-JKTdUmha430D3MWvBW3ISB27pljEniJ-iVa9UkHNljQ27FE1eHT3PFhSS66amr7XCnwBTnwUu3dwZ5fLutv6oKp5qFSN9z1fMHqJ6tC6g5h5MCpRjV6hOm-ElksTgBqYaaozdbVApBvEginc6hV0msHVbsKZKXIE5_p5eLcNhGQLCXUyPnyK91_-Ltw89Pj2SNjKqdgcsU1dM1Xqoa8sN3dfr0lg-36tUmKR2q4FLi4MIb6NB4rrl_4SXx1bApPMnuNQM1efQl54Njht2-wft7Z5for-maxa7eE_HFlU6C-c4Gw5y2B_LoxbyC6CN9G93XJVszahS3d6_wgTU9es75kVPWcf2bjMTS4gXyskXW6Bi0iK_a03CPBIVfkj96zCBHgrKIjIR--OTs5oXJNQ5CO2SNZ9WkNfN01L-DIy0GBrENjwq5eJylqUcrzWPw-JquiSM6QBGQKmfRfzgZ45sIBZBIUOSvrKk4Dm-c5gAK3Jklfg-HF0BXcss0yGIARfmCRev1iPzD74ia1UWLk1IzfrHyxT86kaTbxcXACc181PxV4N36YEp2wu8wBpuTtOdWSpeOPKxe6nyiPFFO2jufi0yyh6tA2vsbv4XCxdHqR1hfn40yIo6PyJUQlM7XzocfmCORiOmHTk33TiHyt2Jnd2G_IDfZINauSX-TSGaK6ORQqEFEkFd0lKf3Ky-wxDWT35btwNIC3s2Fw7Jjs12U-3AUdRABQ6Pud_I8rPQbBzxXj0ly7NTxutFLMdvK3XQb5qljmHzQpJikdl9cc8q1jdBVjflqWVPzYkp1i1ojXJCu_qSPYVmAcFDGS323ku8E
VL  - 24(9)
ER  -
TY  - JOUR
AB  - This review aimed at identifying specific features of PYD interventions with a PA component that appear most promising at reducing bullying behaviors among pre- and early adolescents. We reviewed articles that included PYD interventions with a PA component among pre- and early adolescents aged 8-14 years from five databases and found seven studies representing 3892 participants. 

Studies collectively showed that PYD-PA interventions can promote an interactive and supportive relationship between participants and staff and foster adolescents&#039; psychosocial development. 

The review&#039;s limitations include the variation of PA components and geographical contexts of interventions leading to a difficulty in synthesizing the results. 

PA-based PYD interventions provide a promising approach that can foster youth&#039;s psychosocial development such as the use of an interactive approach and the use of several PYD components (e.g., empathy and caring ). This approach, consequently, may lower bullying behaviors. Given the nature of this review, further evaluation is warranted.
AN  - WOS:000703098300001
AU  - Majed,
AU  - E.
AU  - Ruiz,
AU  - Y.
AU  - Amireault,
AU  - S.
AU  - Reed,
AU  - J.
AU  - B.
AU  - Snyder,
AU  - F.
AU  - J.
AU  - McDonough,
AU  - M.
AU  - H.
AU  - Blankenship,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/02724316211036748
L1  - internal-pdf://0502475659/Majed-Examining Positive Youth Development Int.pdf
PY  - 2021
T2  - Journal of Early Adolescence
TI  - Examining Positive Youth Development Interventions With a Physical Activity Component to Address Bullying Among Pre- and Early Adolescents: A Critical Review of the Literature
UR  - &lt;Go to ISI&gt;://WOS:000703098300001
UR  - https://journals.sagepub.com/doi/pdf/10.1177/02724316211036748
ER  -
TY  - JOUR
AB  - Although most mentoring programs for youth are structured around intergenerational relationships, a growing number of programs rely on cross-age peer mentoring. Such programs capitalize on the availability of youth mentors to promote positive outcomes in younger peers. 

This study used a multilevel meta-analytic approach to estimate the effect size of cross-age peer mentoring programs and evaluate potential moderators of peer mentoring program effectiveness. 

Analyses included six studies and revealed a medium-sized overall effect of cross-age peer mentoring programs (g = 0.45). Several characteristics moderated effect sizes, with larger effects for programs that were conducted outside of the school setting (i.e., weekend, summer, or in community settings), conducted in urban settings, and had moderate/high levels of adult oversight and supervision.

Results highlight the potential benefits of cross-age peer mentoring for youth. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2022-19043-001
AU  - Burton,
AU  - S.
AU  - Raposa,
AU  - E.
AU  - B.
AU  - Poon,
AU  - C.
AU  - Y.
AU  - Stams,
AU  - G.
AU  - J.
AU  - J.
AU  - Rhodes,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/ajcp.12579
L1  - internal-pdf://0538874408/Cross-age peer mentoring for youth_ A met-2021.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - American Journal of Community Psychology
TI  - Cross-age peer mentoring for youth: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-19043-001
UR  - https://onlinelibrary.wiley.com/doi/10.1002/ajcp.12579
ER  -
TY  - JOUR
AB  - **Background**
To evaluate how effective preparatory interventions for paediatric day surgery are at reducing parents&#039; anxiety and stress and children&#039;s pain and fear. 

**Methods**
A systematic review was conducted according to Joanna Briggs Institute (JBI) guidelines and reported using the PRISMA 2020 checklist. PubMed, CINAHL (EBSCO), Scopus, Medic and Web of Science were screened for original research published up until December 2020, while Mednar and EBSCO Open Dissertations were used to identify any relevant grey literature. The methodological quality and risks of bias were evaluated according to JBI guidelines by two authors. The eligibility criteria were parents of a preschool (2- to 6-year-old) child going through day surgery with preparatory interventions, outcomes measured anxiety, stress (parent), fear and pain (child), and randomised controlled trial (RCT). 

**Results**
Two thousand and three hundred and fourteen RCTs were screened. Fifteen studies (including 1514 participants) were chosen for narrative synthesis of parental anxiety and stress and children&#039;s fear and pain. Nine studies underwent a meta-analysis of parental anxiety (n = 970). The interventions were categorised as functional, informative or a combination of both. Four interventions reduced parents&#039; anxiety while two significantly alleviated children&#039;s postoperative pain. The interventions found to be effective combined various ways of providing information. The meta-analysis did reveal a statistically significant impact on parents&#039; anxiety (SMD =0.22, 95% Cl [0.03, 0.41], z = 2.28, p = .023). None of the studies dealt with parental stress or fear in children. 

**Conclusions**
The studied interventions used various preparatory approaches, some of which were effective at reducing parental anxiety. More RCT studies are needed to find the most effective methods for preparing parents and their children for day surgery. Relevance to Clinical Practice Preparation for day surgery through appropriate interventions can reduce anxiety among parents and postoperative pain in children.
AN  - WOS:000726480100001
AU  - Kerimaa,
AU  - H.
AU  - Ruotsalainen,
AU  - H.
AU  - Kyngas,
AU  - H.
AU  - Miettunen,
AU  - J.
AU  - Polkki,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jocn.16156
L1  - internal-pdf://1678779432/Journal of Clinical Nursing - 2021 - Kerimaa -.pdf
PY  - 2021
SP  - 18
T2  - Journal of Clinical Nursing
TI  - Effectiveness of interventions used to prepare preschool children and their parents for day surgery: A systematic review and meta-analysis of randomised controlled trials
UR  - &lt;Go to ISI&gt;://WOS:000726480100001
UR  - https://onlinelibrary.wiley.com/doi/10.1111/jocn.16156
ER  -
TY  - JOUR
AB  - **INTRODUCTION**: Although cash transfer programmes are not explicitly designed to improve mental health, by reducing poverty and improving the life chances of children and young people, they may also improve their mental health. This systematic review and meta-analysis assessed the evidence on the effectiveness of cash transfers to improve the mental health of children and young people in low-income and middle-income countries.

**METHODS**: We searched Pubmed, EBSCOhost, Scientific Electronic Library Online, ISI Web of Science and Social Sciences Citation Index and grey literature (from January 2000 to July 2020) for studies which quantitatively assessed the impact of cash transfers on mental health in young people (aged 0-24 years), using a design that incorporated a control group. We extracted Cohen&#039;s d effects size and used a random-effects model for the meta-analysis on studies that measured depressive symptoms, I&lt;sup&gt;2&lt;/sup&gt; statistic and assessment of study quality.

**RESULTS**: We identified 12 116 articles for screening, of which 12 were included in the systematic review (covering 13 interventions) and seven in the meta-analysis assessing impact on depressive symptoms specifically. There was high heterogeneity (I&lt;sup&gt;2&lt;/sup&gt;=95.2) and a high risk of bias (0.38, 95% CIs: -5.08 to 5.85; p=0.86) across studies. Eleven interventions (85%) showed a significant positive impact of cash transfers on at least one mental health outcome in children and young people. However, no study found a positive effect on all mental health outcomes examined, and the meta-analysis showed no impact of cash transfers on depressive symptoms (0.02, 95% CIs: -0.19 to 0.23; p=0.85).

**CONCLUSION**: Cash transfers may have positive effects on some mental health outcomes for young people, with no negative effects identified. However, there is high heterogeneity across studies, with some interventions showing no effects. Our review highlights how the effect of cash transfers may vary by social and economic context, culture, design, conditionality and mental health outcome.
AD  - Zimmerman, Annie. Health Service &amp; Population Research Department, King&#039;s College London Institute of Psychiatry Psychology and Neuroscience, London, UK annie.zimmerman@kcl.ac.uk.Zimmerman, Annie. Global Health and Social Medicine, King&#039;s College London, London, UK.Garman, Emily. Alan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.Avendano-Pabon, Mauricio. Global Health and Social Medicine, King&#039;s College London, London, UK.Avendano-Pabon, Mauricio. Department of Social and Behavioural Sciences, Harvard School of Public Health, Boston, Massachusetts, USA.Araya, Ricardo. Health Service &amp; Population Research Department, King&#039;s College London Institute of Psychiatry Psychology and Neuroscience, London, UK.Evans-Lacko, Sara. Care Policy and Evaluation Centre, Department of Health Policy, The London School of Economics and Political Science, London, UK.McDaid, David. Care Policy and Evaluation Centre, Department of Health Policy, The London School of Economics and Political Science, London, UK.Park, A-La. Care Policy and Evaluation Centre, Department of Health Policy, The London School of Economics and Political Science, London, UK.Hessel, Philipp. Escuela de Gobierno Alberto Lleras Camargo, Universidad de los Andes, Bogota, Colombia.Diaz, Yadira. Escuela de Gobierno Alberto Lleras Camargo, Universidad de los Andes, Bogota, Colombia.Matijasevich, Alicia. Faculdade de Medicina FMUSP, Departamento de Medicina Preventiva, Universidade de Sao Paulo, Sao Paulo, Brazil.Ziebold, Carola. Faculdade de Medicina FMUSP, Departamento de Medicina Preventiva, Universidade de Sao Paulo, Sao Paulo, Brazil.Bauer, Annette. Care Policy and Evaluation Centre, Department of Health Policy, The London School of Economics and Political Science, London, UK.Paula, Cristiane Silvestre. Programa de Pos-graduacao em Disturbios do Desenvolvimento, Universidade Presbiteriana Mackenzie, Sao Paulo, Brazil.Lund, Crick. Health Service &amp; Population Research Department, King&#039;s College London Institute of Psychiatry Psychology and Neuroscience, London, UK.Lund, Crick. Alan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
AN  - 33906845
AU  - Zimmerman,
AU  - A.
AU  - Garman,
AU  - E.
AU  - Avendano-Pabon,
AU  - M.
AU  - Araya,
AU  - R.
AU  - Evans-Lacko,
AU  - S.
AU  - McDaid,
AU  - D.
AU  - Park,
AU  - A.
AU  - L.
AU  - Hessel,
AU  - P.
AU  - Diaz,
AU  - Y.
AU  - Matijasevich,
AU  - A.
AU  - Ziebold,
AU  - C.
AU  - Bauer,
AU  - A.
AU  - Paula,
AU  - C.
AU  - S.
AU  - Lund,
AU  - C.
DA  - 04
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/bmjgh-2020-004661
DP  - Ovid Technologies
J2  - BMJ glob
L1  - internal-pdf://3665310923/Zimmerman-2021.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Using Smart Source ParsingZimmerman, AnnieGarman, EmilyAvendano-Pabon, MauricioAraya, RicardoEvans-Lacko, SaraMcDaid, DavidPark, A-LaHessel, PhilippDiaz, YadiraMatijasevich, AliciaZiebold, CarolaBauer, AnnettePaula, Cristiane SilvestreLund, Cricke004661
PY  - 2021
SP  - 04
T2  - BMJ Global Health
TI  - The impact of cash transfers on mental health in children and young people in low-income and middle-income countries: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33906845
UR  - https://gh.bmj.com/content/bmjgh/6/4/e004661.full.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - BACKGROUND: Mental health disorders in youth are a global issue that have important implications for the future quality of life and morbidity of affected individuals. In the context of public health initiatives, smartphone-based interventions have been suggested to hold the potential to be an effective strategy to reduce the symptoms of mental health disorders in youth; however, further evaluation is needed to confirm their effectiveness. This systematic review and meta-analysis documents and synthesizes existing research on smartphone-based interventions targeting internalizing disorders in youth populations.

OBJECTIVE: This study aims to synthesize existing research on smartphone-based interventions targeting internalizing disorders in youth populations.

METHODS: PubMed and SCOPUS were searched in 2019, and 4334 potentially relevant articles were found. A total of 12 studies were included in the final synthesis. We used the Hedges g meta-analysis approach and a random effects model for analysis.

RESULTS: The results of this review note that depression and anxiety are the most commonly targeted symptoms, and unlike other similar topics, most studies reviewed were linked to a proven treatment. The overall pooled effect from the meta-analysis showed small but significant effects (kappa=12; N=1370; Hedges g=0.20; 95% CI 0.02-0.38) for interventions in reducing the symptoms of internalizing disorders. In total, 4 subgroup analyses examining specific symptoms and intervention styles found varied small significant and nonsignificant effects.

CONCLUSIONS: Future research should focus on developing robust evaluative frameworks and examining interventions among more diverse populations and settings. More robust research is needed before smartphone-based interventions are scaled up and used at the population level to address youth internalizing disorders.
AD  - Buttazzoni, Adrian. School of Planning, University of Waterloo, Waterloo, ON, Canada.Brar, Keshbir. School of Public Health and Health Systems, University of Waterloo, Waterloo, ON, Canada.Minaker, Leia. School of Planning, University of Waterloo, Waterloo, ON, Canada.
AN  - 33427682
AU  - Buttazzoni,
AU  - A.
AU  - Brar,
AU  - K.
AU  - Minaker,
AU  - L.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.2196/16490
DP  - Ovid Technologies
J2  - J Med Internet Res
L1  - internal-pdf://2509800437/Buttazzoni-2021.pdf
LA  - English
M3  - Review
N1  - Buttazzoni, AdrianBrar, KeshbirMinaker, Leia
PY  - 2021
SP  - e16490
T2  - Journal of Medical Internet Research
TI  - Smartphone-Based Interventions and Internalizing Disorders in Youth: Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33427682
VL  - 23
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: This study aimed to synthesize the best available evidence regarding the effectiveness of non-pharmacological interventions on body mass index (BMI), body dissatisfaction, depression and anxiety among individuals with anorexia nervosa (AN). 

**METHODS**: Published studies in English were searched using seven databases (such as PubMed). Grey literature was searched using ProQuest and Scopus. Studies were screened, appraised and extracted by two independent reviewers. Meta-analysis was performed and standardized mean difference was used as an effect measure. Heterogeneity was determined by I2 statistics and Cochran chi2 test. Publication bias was appraised using funnel plots. Sensitivity and subgroup analyses were also conducted. 

**RESULTS**: Nineteen RCTs from eight different countries were included in this review. Behavioral family system therapy (BFST) was found to enhance BMI while conjoint family therapy (CFT) was more effective in ameliorating depression. Studies implementing combined family and individual therapy and those with longer therapeutic durations produced larger effect sizes. 

**CONCLUSION**: This review provided evidence to support BSFT, CFT and combined family and individual therapy for adolescents with AN. 

**PRACTICAL IMPLICATIONS**: Healthcare professionals may offer the two interventions to adolescents with AN in clinical settings. Future research may further investigate the effectiveness of BSFT and CFT on BMI and depression. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-51912-001
AU  - Gan,
AU  - Javeil
AU  - Ke
AU  - En
AU  - Wu,
AU  - Vivien
AU  - Xi
AU  - Chow,
AU  - Gigi
AU  - Chan,
AU  - Janice
AU  - Kuang
AU  - Yeung
AU  - Klainin-Yobas,
AU  - Piyanee
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.pec.2021.05.031
L1  - internal-pdf://1620417717/Gan-2021-Effectiveness of non-pharmacological.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Patient Education and Counseling
TI  - Effectiveness of non-pharmacological interventions on individuals with anorexia nervosa: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-51912-001
ER  -
TY  - JOUR
AB  - Evidence of the effectivity of play-based interventions in children with autism spectrum disorder (ASD) was evaluated by PRISMA-based literature study and a Risk of Bias (RoB) assessment. Many of the 32 eligible randomized controlled trials (RCT) reported improved social interaction, communication, daily functioning and play behaviour. They also reported decreased problem behaviour, better parental attunement and parent-child interaction. We assessed 25/32 of the RCTs with high RoB, mainly related to homogeneity of the study population, lack of power, and performance bias. 

We concluded with due care that the effectivity of play-based interventions differed across RCTs, most reported improvements are found in ASD symptoms, everyday functioning, and parental attunement. In future research, findings should be replicated, taking account of the RoB.
AN  - WOS:000724632700001
AU  - Dijkstra-de
AU  - Neijs,
AU  - L.
AU  - Tisseur,
AU  - C.
AU  - Kluwen,
AU  - L.
AU  - A.
AU  - Van
AU  - Berckelaer-Onnes,
AU  - I.
AU  - A.
AU  - Swaab,
AU  - H.
AU  - Ester,
AU  - W.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-021-05357-2
L1  - internal-pdf://0575805099/Dijkstra-de Nei-Effectivity of Play-Based Inte.pdf
PY  - 2021
SP  - 30
T2  - Journal of Autism and Developmental Disorders
TI  - Effectivity of Play-Based Interventions in Children with Autism Spectrum Disorder and Their Parents: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000724632700001
UR  - https://link.springer.com/content/pdf/10.1007/s10803-021-05357-2.pdf
ER  -
TY  - JOUR
AB  - Low self-esteem and negative body image expose girls to many risks and damages. Cognitive-behavior counseling is one of the ways of improving body image and self-esteem. The aim of this systematic review was to determine the effects of cognitive-behavior therapy on body image and self-esteem of adolescent girls. 

The English (Cochrane library, Web of sciences, EBSCO, PubMed, Google Scholar) and Persian (SID, MagIran) databases were searched without any time limit. The quality of included studies in terms of risk of bias was assessed using Cochran handbook and the quality of evidence was evaluated through Grading of Recommendations Assessment, Development and Evaluation (GRADE). Meta-analysis was performed using RevMan software. Heterogeneity of studies was analyzed by index I2. Subgroup analysis was performed on the basis of outcome evaluation intervals (after intervention, one month and two months later). 

A total of 2,664 articles were accessed in different databases of which 2,655 articles were excluded and finally nine studies were systematically reviewed. Meta-analysis results on seven studies (228 participants) showed that the group receiving cognitive-behavior counseling was significantly better than the control group regarding body image (Standardized Mean Difference [SMD]: 13.01; 95% CI: 10.68 to 15.34; I2=26.1%). Likewise, meta-analysis results on two studies (50 participants) showed that self-esteem was not significantly different between the group receiving cognitive-behavior counseling and the control group (SMD: 1.13; 95% CI: -0.7 to 2.32, I2=73%). 

Meta-analysis results of this study represent effectiveness of cognitive-behavior therapy on body image of adolescent girls; however, since the number of studies in the field of self-esteem is low, more trials in this field with stronger designs are suggested. Copyright &copy; 2021 Walter de Gruyter GmbH, Berlin/Boston 2021.
AD  - (Zamiri-Miandoab, Kamalifard) Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran, Islamic Republic of (Hassanzadeh) Department of Midwifery, Bonab Branch, Islamic Azad University, Bonab, Iran, Islamic Republic of (Mirghafourvand) Social Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran, Islamic Republic ofM. Mirghafourvand, Social Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran, Islamic Republic of. E-mail: mirghafourvandm@tbzmed.ac.ir
AN  - 2011974230
AU  - Zamiri-Miandoab,
AU  - N.
AU  - Hassanzadeh,
AU  - R.
AU  - Kamalifard,
AU  - M.
AU  - Mirghafourvand,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1515/ijamh-2021-0029
DP  - Ovid Technologies
KW  - adolescents
KW  - body image
KW  - cognitive behavior therapy
KW  - self-esteem
KW  - adolescent
KW  - child
KW  - Cochrane Library
KW  - cognitive behavioral therapy
KW  - controlled study
KW  - counseling
KW  - female
KW  - human
KW  - human experiment
KW  - Medline
KW  - meta analysis
KW  - outcome assessment
KW  - review
KW  - risk assessment
KW  - search engine
KW  - self esteem
KW  - software
KW  - systematic review
KW  - Web of Science
L1  - internal-pdf://2643924957/Zamiri-Miandoab-2021-The effect of cognitive b.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDate of Publication: 2021
PY  - 2021
T2  - International Journal of Adolescent Medicine and Health.
TI  - The effect of cognitive behavior therapy on body image and self-esteem in female adolescents: A systematic review and meta-analysis
UR  - http://www.degruyter.com/view/j/ijamh?rskey=qYlGDI&amp;result=1&amp;q=International%20Journal%20of%20Adolescent%20Medicine%20and%20Health
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2011974230
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33915608&amp;id=doi:10.1515%2Fijamh-2021-0029&amp;issn=0334-0139&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=International+Journal+of+Adolescent+Medicine+and+Health&amp;atitle=The+effect+of+cognitive+behavior+therapy+on+body+image+and+self-esteem+in+female+adolescents%3A+A+systematic+review+and+meta-analysis&amp;aulast=Zamiri-Miandoab&amp;pid=%3Cauthor%3EZamiri-Miandoab+N.%3C%2Fauthor%3E%3CAN%3E2011974230%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - This article reviewed behavioral treatment of restricted and repetitive behavior and interests (RRBIs) specifically for children with autism spectrum disorder (ASD) 8 years of age and younger. 

Empirical studies published in the last decade that examined the effects of behavioral interventions for RRBIs in young children with ASD were reviewed. Electronic database and ancestral searches identified 31 studies meeting inclusion criteria (104 participants). Results indicated antecedent-based interventions were the most common for lower- order RRBIs (L-RRBIs), while multicomponent treatment packages were the most common for higher-order RRBIs (H-RRBIs). Consequence-based strategies were more effective in decreasing L-RRBIs. Few studies examined H-RRBIs and natural change agents were seldom included in RRBI interventions. 

Limitations and implications for future research were discussed. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2021-61841-001
AU  - Wei,
AU  - Q.
AU  - Machalicek,
AU  - W.
AU  - Crowe,
AU  - B.
AU  - Kunze,
AU  - M.
AU  - Rispoli,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - Tom verdi
L1  - internal-pdf://3423054295/Restricted and repetitive patterns of beh-2021.pdf
PY  - 2021
SP  - 115-139
T2  - Education and Training in Autism and Developmental Disabilities
TI  - Restricted and repetitive patterns of behavior and interests in children with autism spectrum disorder: A systematic review of behavioral interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2021-61841-001
VL  - 56
ER  -
TY  - JOUR
AB  - Bullying and cyberbullying are important risk factors for the mental health of adolescents. Bullying is defined as an intentional aggression, repeated on time, and characterized by a difference of powers between the victim and the aggressor. Cyberbullying is an aggression with the same characteristics of the bullying but carried out on the cyberspace. Despite the relevance of this problem, there is no meta-analysis that determines the effectiveness of interventions directed to reduce both problems. In this way, the objective of this book chapter is to present meta-analysis that addresses the effectiveness of interventions directed to reduce bullying, victimization, cyberbullying, and cybervictimization in adolescents. 

A systematic review of scientific papers published in Spanish, English, and Portuguese was conducted between 2000 and 2018. The databases included were as follows: SciELO, PubMed, JSTOR, Dialnet, EBSCO, Latindex, and PsycINFO. 

After the research, 16 articles were included in the traditional bullying meta-analysis, 14 articles were included in the traditional victimization meta-analysis, 11 articles were included in the cyberbullying meta-analysis, and finally 8 articles were included in the cybervictimization meta-analysis. The size of the effect of bullying and cyberbullying interventions was analysed to establish which one is more effective. 

Comparing bullying and cyberbullying, the results of the present study indicated that bullying programmes were a bit more effective than cyberbullying programmes, while the effect size of the intervention programme on victimization and cybervictimization were similar. Explanations about why interventions on bullying are more successful and implications of these findings are provided and analysed in the conclusion. Finally, suggestions for future studies are discussed. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2021-36801-032
AU  - Resett,
AU  - S.
AU  - Mesurado,
AU  - B.
DB  - Alerts 6_2022.enl
DO  - /10.1007/978-3-030-61721-9_32
L1  - internal-pdf://1967902198/Resett-2021-Bullying and cyberbullying in adol.pdf
PY  - 2021
SP  - 445-458
T2  - Gargiulo, Pascual Angel [Ed]; Mesones Arroyo, Humberto Luis [Ed] (2021) Psychiatry and neuroscience update: From epistemology to clinical psychiatry , Vol 4
TI  - Bullying and cyberbullying in adolescents: A meta-analysis on the effectiveness of interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2021-36801-032
UR  - https://link.springer.com/chapter/10.1007/978-3-030-61721-9_32
UR  - https://link.springer.com/content/pdf/10.1007/978-3-030-61721-9_32.pdf
ER  -
TY  - JOUR
AB  - **BACKGROUND**: To evaluate the effect of recombinant human erythropoietin (rhEPO) in nervous system of premature infants including different dosage.METHODS: The multiple databases like Pubmed, Embase, Cochrane databases and China National Knowledge Database were used to search for the relevant studies, and full-text articles involved in the evaluation on effect of rhEPO for neurodevelopment among premature infants. Review Manager 5.2 was adopted to estimate the effects of the results among selected articles. Forest plots, sensitivity analysis and bias analysis for the articles included were also conducted.

**RESULTS**: Finally, 10 eligible studies were eventually satisfied the included criteria. The results showed that rhEPO was much higher than placebo group in composite cognitive score (MD = 5.89, 95% confidential interval {CI} [1.95, 9.82], P = .003; I2 = 89%), there was no significant difference between rhEPO and placebo groups (RR = 0.93, 95% CI [0.60, 1.43], P = .74; I2 = 51%) and no difference in neurodevelopmental impairment between rhEPO and placebo was insignificant (RR = 0.55 95% CI [0.30, 1.02], P = .06). Composite cognitive score in high dose rhEPO was much higher than placebo group (MD = 10.39, 95% CI [8.84, 11.93], P &lt; .0001, I2 = 0%) and low dose rhEPO also had higher composite cognitive score than placebo group (MD = 2.58, 95% CI [0.80, 4.37], P = .004, I2 = 11%). Limited publication bias was observed in this study.

**CONCLUSION**: Recombinant human erythropoietin might be a promotor for neurodevelopment among premature infants with limited adverse events.
AD  - Qin, Na. Heping Hospital Affiliated to Changzhi Medical College, Changzhi City, Shanxi Province, China.
AN  - 33950982
AU  - Qin,
AU  - N.
AU  - Qin,
AU  - H.
DA  - May 07
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/MD.0000000000025805
DP  - Ovid Technologies
J2  - Medicine (Baltimore)
KW  - *Child Development/de [Drug Effects]
KW  - Dose-Response Relationship, Drug
KW  - *Erythropoietin/ad [Administration &amp; Dosage]
KW  - Erythropoietin/ae [Adverse Effects]
KW  - Humans
KW  - Infant, Newborn
KW  - *Infant, Premature/gd [Growth &amp; Development]
KW  - Nervous System/de [Drug Effects]
KW  - *Nervous System/gd [Growth &amp; Development]
KW  - *Neurodevelopmental Disorders/pc [Prevention &amp; Control]
KW  - Recombinant Proteins/ad [Administration &amp; Dosage]
KW  - Recombinant Proteins/ae [Adverse Effects]
KW  - Treatment Outcome
KW  - 0 (EPO protein, human)
KW  - 0 (Recombinant Proteins)
KW  - 11096-26-7 (Erythropoietin)
L1  - internal-pdf://3624483667/Qin-2021-Efficacy and safety of high and low d.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Qin, NaQin, Huibin
PY  - 2021
SP  - e25805
T2  - Medicine
TI  - Efficacy and safety of high and low dose recombinant human erythropoietin on neurodevelopment of premature infants: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=33950982
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33950982&amp;id=doi:10.1097%2FMD.0000000000025805&amp;issn=0025-7974&amp;isbn=&amp;volume=100&amp;issue=18&amp;spage=e25805&amp;pages=e25805&amp;date=2021&amp;title=Medicine&amp;atitle=Efficacy+and+safety+of+high+and+low+dose+recombinant+human+erythropoietin+on+neurodevelopment+of+premature+infants%3A+A+meta-analysis.&amp;aulast=Qin&amp;pid=%3Cauthor%3EQin+N%3C%2Fauthor%3E%3CAN%3E33950982%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8104141/pdf/medi-100-e25805.pdf
VL  - 100
ER  -
TY  - JOUR
AB  - Emotion regulation (ER) is the ability to monitor, evaluate, and modify one&#039;s emotional responses to be appropriate for environmental demands. Poor ER has been considered a transdiagnostic risk factor for a range of internalizing and externalizing disorders and overall decreased well-being in adolescents. A range of evidence-based interventions exist which may improve ER. However, much of the intervention research to date does not include a measure of ER to assess change pre and post treatment, with limited information about the efficacy of these interventions in youth across a range of sample types. There is a clear need for a comprehensive review of the literature examining ER-focused interventions in adolescents with a wide range of presenting disorders.

A literature search was originally conducted in January 2020 and an updated search was conducted in February 2021 which elicited 1245 articles, of which 605 were duplicates and were removed. Abstracts of the remaining 640 articles were screened with 121 articles being reviewed in full. Of note, 16 additional articles were identified through references and other sources during this process and were also included in the full review. Of the 137 articles reviewed in full, 41 studies were ultimately included in the present review. The present paper provides a descriptive review of intervention approaches and findings from community prevention programs, programs for war-affected youth, programs for clinical populations, and programs for incarcerated and delinquent adolescents. 

The overall pooled effect was significantly different from zero based on the pre/post effects [Hedge&#039;s g = 0.29, 95% CI (0.22, 0.36)] and the intervention/control effects [Hedge&#039;s g = 0.19, 95% CI (0.06-0.32)]. Although neither sex nor age significantly accounted for heterogeneity in effect sizes, there were significant findings for population type (clinical vs. community), with community samples having significantly lower effect sizes on average. Impacts of the different ER measures used and significant methodological variability (e.g., use of control groups, length of intervention) across included studies are discussed. 

Implications and suggestions for future research are reviewed, specifically, that additional understanding of moderators of effects are needed and that measures used to assess change in ER, both dysregulation and adaptive skill use, may need to more directly align with the intervention&#039;s focus and the strategies taught as part of the intervention.
AN  - WOS:000674207900001
AU  - Eadeh,
AU  - H.
AU  - M.
AU  - Breaux,
AU  - R.
AU  - Nikolas,
AU  - M.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-021-00362-4
L1  - internal-pdf://0355044426/Eadeh-A Meta-Analytic Review of Emotion Regula.pdf
PY  - 2021
SP  - 23
T2  - Clinical Child and Family Psychology Review
TI  - A Meta-Analytic Review of Emotion Regulation Focused Psychosocial Interventions for Adolescents
UR  - &lt;Go to ISI&gt;://WOS:000674207900001
UR  - https://link.springer.com/content/pdf/10.1007/s10567-021-00362-4.pdf
ER  -
TY  - JOUR
AB  - Abstract **Background** Almost two billion people who are deficient in vitamins and minerals are women and children in low- and middle-income countries (LMIC). These deficiencies are worsened during pregnancy due to increased energy and nutritional demands, causing adverse outcomes in mother and child. To reduce micronutrient deficiencies, several strategies have been implemented, including diet diversification, large-scale and targeted fortification, staple crop bio-fortification and micronutrient supplementation. Objectives To evaluate and summarize the available evidence on the effects of micronutrient supplementation during pregnancy in LMIC on maternal, fetal, child health and child development outcomes. This review will assess the impact of single micronutrient supplementation (calcium, vitamin A, iron, vitamin D, iodine, zinc, vitamin B12), iron-folic acid (IFA) supplementation, multiple micronutrient (MMN) supplementation, and lipid-based nutrient supplementation (LNS) during pregnancy. 

**Search Methods** We searched papers published from 1995 to 31 October 2019 (related programmes and good quality studies pre-1995 were limited) in CAB Abstracts, CINAHL, Cochrane Central Register of Controlled Trials, Embase, International Initiative for Impact Evaluations, LILACS, Medline, POPLINE, Web of Science, WHOLIS, ProQuest Dissertations &amp; Theses Global, R4D, WHO International Clinical Trials Registry Platform. Non-indexed grey literature searches were conducted using Google, Google Scholar, and web pages of key international nutrition agencies. Selection Criteria We included randomized controlled trials (individual and cluster-randomized) and quasi-experimental studies that evaluated micronutrient supplementation in healthy, pregnant women of any age and parity living in a LMIC. LMIC were defined by the World Bank Group at the time of the search for this review. While the aim was to include healthy pregnant women, it is likely that these populations had one or more micronutrient deficiencies at baseline; women were not excluded on this basis. Data Collection and Analysis Two authors independently assessed studies for inclusion and risk of bias, and conducted data extraction. Data were matched to check for accuracy. Quality of evidence was assessed using the GRADE approach. 

**Main Results** A total of 314 papers across 72 studies (451,723 women) were eligible for inclusion, of which 64 studies (439,649 women) contributed to meta-analyses. Seven studies assessed iron-folic acid (IFA) supplementation versus folic acid; 34 studies assessed MMN vs. IFA; 4 studies assessed LNS vs. MMN; 13 evaluated iron; 13 assessed zinc; 9 evaluated vitamin A; 11 assessed vitamin D; and 6 assessed calcium. Several studies were eligible for inclusion in multiple types of supplementation. IFA compared to folic acid showed a large and significant (48%) reduction in the risk of maternal anaemia (average risk ratio (RR) 0.52, 95% CI 0.41 to 0.66; studies = 5; participants = 15,540; moderate-quality evidence). As well, IFA supplementation demonstrated a smaller but significant, 12% reduction in risk of low birthweight (LBW) babies (average RR 0.88, 95% CI 0.78 to 0.99; studies = 4; participants = 17,257; high-quality evidence). MMN supplementation was defined as any supplement that contained at least 3 micronutrients. Post-hoc analyses were conducted, where possible, comparing the differences in effect of MMN with 4+ components and MMN with 3 or 4 components. When compared to iron with or without FA, MMN supplementation reduced the risk of LBW by 15% (average RR 0.85, 95% CI 0.77 to 0.93; studies = 28; participants = 79,972); this effect was greater in MMN with &gt;4 micronutrients (average RR 0.79, 95% CI 0.71 to 0.88; studies = 19; participants = 68,138 versus average RR 1.01, 95% CI 0.92 to 1.11; studies = 9; participants = 11,834). There was a small and significant reduction in the risk of stillbirths (average RR 0.91; 95% CI 0.86 to 0.98; studies = 22; participants = 96,772) and a small and significant effect on the risk of small-for-gestational age (SGA) (average RR 0.93; 95% CI 0.88 to 0.98; studies = 19; participants = 52,965). For stillbirths and SGA, the effects were greater among those provided MMN with 4+ micronutrients. Children whose mothers had been supplemented with MMN, compared to IFA, demonstrated a 16% reduced risk of diarrhea (average RR 0.84; 95% CI 0.76 to 0.92; studies = 4; participants = 3,142). LNS supplementation, compared to MMN, made no difference to any outcome; however, the evidence is limited. Iron supplementation, when compared to no iron or placebo, showed a large and significant effect on maternal anaemia, a reduction of 47% (average RR 0.53, 95% CI 0.43 to 0.65; studies = 6; participants = 15,737; moderate-quality evidence) and a small and significant effect on LBW (average RR 0.88, 95% CI 0.78 to 0.99; studies = 4; participants = 17,257; high-quality evidence). Zinc and vitamin A supplementation, each both compared to placebo, had no impact on any outcome examined with the exception of potentially improving serum/plasma zinc (mean difference (MD) 0.43 umol/L; 95% CI &minus;0.04 to 0.89; studies = 5; participants = 1,202) and serum/plasma retinol (MD 0.13 umol/L; 95% CI &minus;0.03 to 0.30; studies = 6; participants = 1,654), respectively. When compared to placebo, vitamin D supplementation may have reduced the risk of preterm births (average RR 0.64; 95% CI 0.40 to 1.04; studies = 7; participants = 1,262), though the upper CI just crosses the line of no effect. Similarly, calcium supplementation versus placebo may have improved rates of pre-eclampsia/eclampsia (average RR 0.45; 95% CI 0.19 to 1.06; studies = 4; participants = 9,616), though the upper CI just crosses 1. 

**Authors&#039; Conclusions** The findings suggest that MMN and vitamin supplementation improve maternal and child health outcomes, including maternal anaemia, LBW, preterm birth, SGA, stillbirths, micronutrient deficiencies, and morbidities, including pre-eclampsia/eclampsia and diarrhea among children. MMN supplementation demonstrated a beneficial impact on the most number of outcomes. In addition, MMN with &gt;4 micronutrients appeared to be more impactful than MMN with only 3 or 4 micronutrients included in the tablet. Very few studies conducted longitudinal analysis on longer-term health outcomes for the child, such as anthropometric measures and developmental outcomes; this may be an important area for future research. This review may provide some basis to guide continual discourse around replacing IFA supplementation with MMN along with the use of single micronutrient supplementation programs for specific outcomes.
AU  - Keats,
AU  - Emily
AU  - C.
AU  - Oh,
AU  - Christina
AU  - Chau,
AU  - Tamara
AU  - Khalifa,
AU  - Dina
AU  - S.
AU  - Imdad,
AU  - Aamer
AU  - Bhutta,
AU  - Zulfiqar
AU  - A.
DB  - My EndNote Library.enl
DO  - /10.1002/cl2.1127
PY  - 2021
SP  - e1127
T2  - Campbell Systematic Reviews
TI  - Effects of vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low- and middle-income countries: A systematic review
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/cl2.1127
VL  - 17
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: To systematically evaluate the clinical efficacy and safety of acupuncture in the treatment of Tic Disorders (TD) in children, and to clarify the current evidence regarding the clinical application of acupuncture in the treatment of TD.

**METHODS**: Randomized controlled trials (RCTs) comparing acupuncture treatment with pharmaceutical treatment for TD were included in this review. A comprehensive search of 6 electronic literature databases was conducted, and the retrieval date was from the establishment of the database to April 2020. The Cochrane Collaboration&#039;s bias risk assessment tool was used to evaluate the bias risk of the included literature, and adopted the Review Manager 5.3 was used for statistical analysis of the data in the included literature.

**RESULTS**: A total of 22 RCTs (1668 participants) were included in this review. Meta-analysis indicated that acupuncture showed superior effects in the following aspects, including higher overall effective rate [RR = 1.20,95 % CI(1.09,1.20),P&lt;0.00001], significant reduction in Yale Global Tic Severity Scale (YGTSS) scores [MD=-2.79,95 %CI(-4.75,-0.82),P = 0.005], lower incidence of adverse effects [RR = 0.26,95 %CI(0.17,0.41),P&lt;0.00001], and reduced recurrence rate [RR = 0.28,95 %CI(0.17,0.46),P&lt;0.00001].CONCLUSION: Acupuncture treatment alone is more effective in the treatment of TD than pharmaceutical treatment, as seen in the reduction of YGTSS scores, fewer adverse effects and lower recurrence rates.
AD  - Lu, Chen. Beijing University of Chinese Medicine, No. 11 Beisanhuan East Road, Chaoyang District, Beijing, 100029, China. Electronic address: 15811103552@163.com.Wu, Li-Qun. Dongfang Hospital,Beijing University of Chinese Medicine, No. 6, Fangxingyuan District 1, Fengtai District, Beijing, 100078, China. Electronic address: Wulq1211@163.com.Hao, Hongwen. Dongfang Hospital,Beijing University of Chinese Medicine, No. 6, Fangxingyuan District 1, Fengtai District, Beijing, 100078, China. Electronic address: 13501380684@163.com.Kimberly Leow, Xinting. Beijing University of Chinese Medicine, No. 11 Beisanhuan East Road, Chaoyang District, Beijing, 100029, China. Electronic address: kleow001@e.ntu.edu.sg.Xu, Fang-Wei. Beijing University of Chinese Medicine, No. 11 Beisanhuan East Road, Chaoyang District, Beijing, 100029, China. Electronic address: 13071182105@163.com.Li, Pan-Pan. Beijing University of Chinese Medicine, No. 11 Beisanhuan East Road, Chaoyang District, Beijing, 100029, China. Electronic address: panpanli0210@163.com.Wang, Dong-Sheng. Beijing University of Chinese Medicine, No. 11 Beisanhuan East Road, Chaoyang District, Beijing, 100029, China. Electronic address: growandso@163.com.
AN  - 33989798
AU  - Lu,
AU  - C.
AU  - Wu,
AU  - L.
AU  - Q.
AU  - Hao,
AU  - H.
AU  - Kimberly
AU  - Leow,
AU  - X.
AU  - Xu,
AU  - F.
AU  - W.
AU  - Li,
AU  - P.
AU  - P.
AU  - Wang,
AU  - D.
AU  - S.
DA  - May 11
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ctim.2021.102734
DP  - Ovid Technologies
J2  - Complement Ther Med
L1  - internal-pdf://1051397782/1-s2.0-S0965229921000753-main.cleaned.pdf
LA  - English
M3  - Review
N1  - Lu, ChenWu, Li-QunHao, HongwenKimberly Leow, XintingXu, Fang-WeiLi, Pan-PanWang, Dong-ShengS0965-2299(21)00075-3
PY  - 2021
SP  - 102734
T2  - Complementary Therapies in Medicine
TI  - Clinical efficacy and safety of acupuncture treatment of TIC disorder in children: A systematic review and meta-analysis of 22 randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33989798
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33989798&amp;id=doi:10.1016%2Fj.ctim.2021.102734&amp;issn=0965-2299&amp;isbn=&amp;volume=59&amp;issue=&amp;spage=102734&amp;pages=102734&amp;date=2021&amp;title=Complementary+Therapies+in+Medicine&amp;atitle=Clinical+efficacy+and+safety+of+acupuncture+treatment+of+TIC+disorder+in+children%3A+A+systematic+review+and+meta-analysis+of+22+randomized+controlled+trials.&amp;aulast=Lu&amp;pid=%3Cauthor%3ELu+C%3C%2Fauthor%3E%3CAN%3E33989798%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 59
ER  -
TY  - JOUR
AB  - **ABSTRACT**
This review evaluated the evidence for narrative intervention on language and pragmatic outcomes for school-aged children with autism spectrum disorder (ASD). The study protocol for this review followed the PRISMA-Protocol checklist and was pre-registered on Open Science Framework. Ten electronic databases were searched to identify experimental designs studies that targeted school-aged children aged 5-18 with ASD. Two independent reviewers evaluated the inclusion eligibility of full-text studies. All included studies were critically appraised by two independent reviewers. Data were coded for study characteristics and outcomes of interest. Results from different outcome measures were synthesized qualitatively. The report was reviewed with the PRISMA checklist to ensure complete reporting. Forty participants from seven studies were included in this review. Six single-case experimental design studies and one group study were included. All these studies included methodological flaws that reduced the strength of evidence. The results indicated that narrative intervention might have large effects on comprehension of discourse, medium effects on production of macrostructure and microstructure, and small effects on pragmatic skills compared to pretreatment. For maintenance effects and other outcome constructs, including pragmatic skills, it was inconclusive whether the narrative intervention had true effects. Evidence from this review suggests that narrative intervention may produce medium-size effects on several constructs of language outcomes. Nonetheless, there was no evidence that showed those gains could be maintained post-treatment. The methodological weaknesses and the small sample of included studies restrict stronger conclusions from being drawn. More high-quality group studies with clearly described treatment procedures are needed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-99001-001
AU  - Tam,
AU  - J.
AU  - Y.
AU  - C.
AU  - Barrett,
AU  - E.
AU  - A.
AU  - Ho,
AU  - A.
AU  - Y.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/2050571X.2021.1985893
L1  - internal-pdf://1571531571/Tam-2021-Narrative intervention in school-aged.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Speech, Language and Hearing
TI  - Narrative intervention in school-aged children with autism spectrum disorder: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-99001-001
UR  - https://www.tandfonline.com/doi/full/10.1080/2050571X.2021.1985893
ER  -
TY  - JOUR
AB  - **INTRODUCTION**: Brain function deficits cause strong negative impacts for the everyday lives of children and adolescents with fetal alcohol spectrum disorders (FASD). Therefore, evidence-based intervention programs that are specifically designed for patients with FASD are needed but still scarce. The aim of the presented article is a systematic literature review of evidence-based intervention strategies for children and adolescents with FASD. 

**MATERIALS AND METHODS**: A comprehensive systematic literature search was conducted in several relevant databases to identify randomized-controlled intervention studies for children and adolescents with FASD. 

**RESULTS**: We identified 25 randomized-controlled studies regarding interventions in FASD. Overall, evidence indicating that some therapeutic interventions are effective in children and adolescents with FASD was found. Even though evidence-based interventions rarely lead to improvements of performance into a &quot;normal range&quot;, those measures can alleviate negative consequences of prenatal alcohol exposure and relieve daily burdens. 

**CONCLUSION**: There are only a few randomized-controlled trials regarding therapy research for children and adolescents with FASD. Their results indicate that especially the combination of parent and child sessions present a promising approach for the treatment of FASD. Positive treatment effects of interventions seem to be domain specific, except for interventions regarding self-regulation or social interaction.
AN  - 34058625
AU  - Ordenewitz,
AU  - L.
AU  - K.
AU  - Weinmann,
AU  - T.
AU  - Schluter,
AU  - J.
AU  - A.
AU  - Moder,
AU  - J.
AU  - E.
AU  - Jung,
AU  - J.
AU  - Kerber,
AU  - K.
AU  - Greif-Kohistani,
AU  - N.
AU  - Heinen,
AU  - F.
AU  - Landgraf,
AU  - M.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ejpn.2021.02.001
L1  - internal-pdf://3642082823/Ordenewitz-2021-Evidence-based interventions f.pdf
PY  - 2021
SP  - 50-60
T2  - European Journal of Paediatric Neurology
TI  - Evidence-based interventions for children and adolescents with fetal alcohol spectrum disorders - A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34058625
UR  - https://www.ejpn-journal.com/article/S1090-3798(21)00013-1/fulltext
VL  - 33
ER  -
TY  - JOUR
AB  - Studies have reported that physical exercise reduces maladaptive stereotyped motor behaviours (SMB) in children with ASD, but these intervention studies vary in design and outcome. The present systematic review and meta-analysis included 22 studies, involving 274 children with ASD, to quantify the effect of exercise on SMB and its potential moderators. Multi-level modelling revealed a large overall effect, Hedges&#039; g = 1.16, with significant heterogeneity across participant, treatment, and study levels. Further, a more appropriate model using between-case estimation for within-subject effects to improve comparability between single-case and group-design studies, yielded a smaller but still significant effect, g = 0.51. Lastly, higher exercise intensity, but not age, exercise duration or settings, reliably predicted treatment effectiveness. Implications for clinical practice and research are discussed.
AN  - WOS:000670844900001
AU  - Teh,
AU  - E.
AU  - J.
AU  - Vijayakumar,
AU  - R.
AU  - Tan,
AU  - T.
AU  - X.
AU  - J.
AU  - Yap,
AU  - M.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-021-05152-z
L1  - internal-pdf://0026012295/Teh-Effects of Physical Exercise Interventions.pdf
PY  - 2021
SP  - 24
T2  - Journal of Autism and Developmental Disorders
TI  - Effects of Physical Exercise Interventions on Stereotyped Motor Behaviours in Children with ASD: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000670844900001
UR  - https://link.springer.com/content/pdf/10.1007/s10803-021-05152-z.pdf
ER  -
TY  - JOUR
AB  - Internet- and mobile-based interventions (IMIs) are being developed for a wide range of psychological disorders and they showed their effectiveness in multiple studies. Specific phobia (SP) is one of the most common anxiety disorders, and research about IMIs for their treatment has also been conducted in recent years. The aim of this paper was to conduct a systematic review and preliminary meta-analysis exploring IMIs for the treatment of SP. A comprehensive search conducted in five different databases identified 9 studies (4 pre-post studies, 5 randomized controlled trials) with 7 Internet-based interventions and 2 mobile-based interventions. Results showed that exposure was the main component of all interventions, and that animal phobia was the most common subtype. Samples included children, adolescents, and adults. A preliminary meta-analysis of the included studies showed that participants receiving IMIs experienced a significant reduction of SP symptoms from pre- to post-treatment (g = 1.15). This systematic review found that there is already some evidence in the literature supporting the potential benefits of IMIs for SP. However, the number of studies included is small and more research should be carried out in the field. Copyright &copy; 2021
AN  - 2014945177
AU  - Mor,
AU  - S.
AU  - Grimaldos,
AU  - J.
AU  - Tur,
AU  - C.
AU  - Miguel,
AU  - C.
AU  - Cuijpers,
AU  - P.
AU  - Botella,
AU  - C.
AU  - Quero,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.invent.2021.100462
L1  - internal-pdf://1604171452/Mor-2021-Internet- and mobile-based interventi.pdf
PY  - 2021
T2  - Internet Interventions
TI  - Internet- and mobile-based interventions for the treatment of specific phobia: A systematic review and preliminary meta-analysis
UR  - http://www.journals.elsevier.com/internet-interventions/
VL  - 26 (no pagination)
ER  -
TY  - JOUR
AB  - BAKGRUNN
Formålet med denne artikkelen er en kunnskapsoppsummering og klassifisering av tiltaket B4DT for tvangslidelse/OCD rettet mot barn og unge i alderen 11&ndash;18 år.

Tiltaket er rettet mot barn med en diagnostisert tvangslidelse og formålet med behandlingen er en lettelse i symptomer på denne lidelsen og bedre fungering i dagliglivet. Det teoretiske grunnlaget for tiltaket er kognitiv atferdsterapi og spesielt eksponeringsterapi med responsprevensjon, hvor ungdommen skal utsette seg for stimuli eller situasjoner som fremkaller frykt og samtidig unnlate å utføre tvangshandlingene. Tilbudet gis over 4 dager og karakteriseres som en konsentrert behandling. B4DT tilbys i spesialisthelsetjenesten. Barn og foreldre får tiltaket i gruppe hvor det er en terapeut for hver pasient. Helse Bergen HF og Klinikk for 4-dagers behandling ved Haukeland sykehus er ansvarlig for tiltaket i Norge.

METODE
Kunnskapsoppsummeringen bygger på et systematisk søk fra databasene Embase, Medline og Psyk Info, NORART, Cochrane, Cristin, NORA, SCOPUS, SweMed, Cambell, NREPP, NICE, Blueprint og CEBC samt materiell fra tiltakseier. Søket ble gjennomgått for å identifisere nordiske effektstudier, internasjonale kunnskapsoppsummeringer samt annen relevant informasjon om tiltaket. To nordiske artikler ble identifisert i den aktuelle aldersgruppen og disse ble inkludert i kunnskapsoppsummeringen.

RESULTATER
Resultatene innbefatter en oppsummering av tiltakets beskrivelse, inkluderte forskningsstudier, forskningsmetodisk kvalitet og implementeringskvalitet. B4DT bygger på teori som er godt beskrevet i litteratur om OCD. Målgrupper og målsetting er godt beskrevet, men det foreligger ikke en manual som beskriver gjennomføring av tiltaket. Etablerte måleinstrumenter er benyttet og tiltaket er gjennomført i vanlig klinisk praksis. De inkluderte studiene undersøker effekt i et pre-post-design uten kontrollgruppe, og det er ikke rapportert bruk av sjekkliste eller video-analyser for å kvalitetssikre behandlingens innhold. Det er beskrevet omfattende opplæring og kvalifikasjonskrav, og veiledning for å opprettholde kvalitet hvis resultat faller under forventet standard. Resultatene er positive med store effektstørrelser for tvangssymptomer for ungdom i alderen 11&ndash;18 år, men små utvalg gjør at den presise størrelsen på effektene ikke kan fastslås.

KONKLUSJON
B4DT for tvangslidelse hos barn og unge i alderen 11&ndash;18 år klassifiseres på evidensnivå 3: Tiltak med noe dokumentasjon på effekt.
AU  - Martinsen,
AU  - K.
AU  - D.,
AU  - Rognli,
AU  - E.,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2021
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: The Bergen 4-Day Treatment (B4DT) (1. utg)
UR  - https://ungsinn.no/post_tiltak_arkiv/the-bergen-4-day-treatment-b4dt-1-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Anxiety is common in youth on the autism spectrum and cognitive behavioural therapy (CBT) has been adapted to address associated symptoms. The aim of the current systematic review and meta-analysis was to examine the efficacy of CBT for reducing anxiety in autistic youth. 

**METHOD**
Searches of PubMed and Scopus databases were undertaken from January 1990 until December 2020. Studies were included if they consisted of randomised controlled trials (RCTs) using CBT to reduce anxiety in autistic youth. Separate random effects meta-analyses assessed anxiety ratings according to informant (clinician; parent; child), both at end-of-trial and at follow-up. 

**RESULTS**
A total of 19 RCTs met our inclusion criteria (833 participants: CBT N = 487; controls N = 346). Random effects meta-analyses revealed a large effect size for clinician rated symptoms (g = 0.88, 95% CI 0.55, 1.12, k = 11), while those for both parent (g = 0.40, 95% CI 0.24, 0.56; k = 18) and child-reported anxiety (g = 0.25, 95% CI 0.06, 0.43; k = 13) were smaller, but significant. These benefits were not however maintained at follow-up. Moderator analyses showed that CBT was more efficacious for younger children (for clinician and parent ratings) and when delivered as individual therapy (for clinician ratings). Using the Cochrane Risk of Bias 2 tool, we found concerns about reporting bias across most trials. 

**CONCLUSIONS**
The efficacy of CBT for anxiety in autistic youth was supported in the immediate intervention period. However, substantial inconsistency emerged in the magnitude of benefit depending upon who was rating symptoms (clinician, parent or child). Follow-up analyses failed to reveal sustained benefits, though few studies have included this data. It will be important for future trials to address robustness of treatment gains overtime and to further explore inconsistency in efficacy by informant. We also recommend pre-registration of methods by trialists to address concerns with reporting bias.
AN  - 34598734
AU  - Sharma,
AU  - S.
AU  - Hucker,
AU  - A.
AU  - Matthews,
AU  - T.
AU  - Grohmann,
AU  - D.
AU  - Laws,
AU  - K.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s40359-021-00658-8
L1  - internal-pdf://2206772472/Sharma-2021-Cognitive behavioural therapy for.pdf
PY  - 2021
SP  - 151
T2  - BMC psychology
TI  - Cognitive behavioural therapy for anxiety in children and young people on the autism spectrum: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34598734
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487131/pdf/40359_2021_Article_658.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - The efficacy and tolerability of repetitive transcranial magnetic stimulation (rTMS) in major depression is wellknown and documented by existing studies. However, whether rTMS may be effective on suicidal behavior is unclear and needs to be further investigated. This systematic review is aimed to investigate the available literature about the effects of rTMS on suicidal behavior and provide a comprehensive overview of the available evidence. 

A systematic search regarding the association between rTMS and suicidal behavior was carried out. All relevant articles concerning this association were comprehensively searched on PubMed, Scopus, Science Direct, and PsycInfo databases. After a careful search, 16 articles (7 sham-controlled studies, 5 uncontrolled studies, 4 case-series) met inclusion criteria and were selected in this systematic review. Overall, the left dorsolateral prefrontal cortex (DLPFC) was identified as the most frequent stimulation target by most studies. Unfortunately, actually it is not clear whether suicidal behavior reduction may be mediated, at least in some cases, by depression attenuation. While some methodological heterogeneity was found in terms of stimulation parameters (e.g., frequency, number of sessions, intensity of stimulation), most of the analyzed articles showed that rTMS is a safe, applicable, well tolerated and reproducible method in treating suicidal behavior. The most effective treatment seems to be the bilateral rTMS as well as the combination with antidepressants. Further longitudinal studies are required in order to replicate the mentioned study results.
AN  - WOS:000600415100009
AU  - Serafini,
AU  - G.
AU  - Canepa,
AU  - G.
AU  - Aguglia,
AU  - A.
AU  - Amerio,
AU  - A.
AU  - Bianchi,
AU  - D.
AU  - Magnani,
AU  - L.
AU  - Dell&#039;Osso,
AU  - B.
AU  - Pompili,
AU  - M.
AU  - Fitzgerald,
AU  - P.
AU  - B.
AU  - Amore,
AU  - M.
DA  - MAR 8
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.pnpbp.2020.109981
L1  - internal-pdf://1813058049/Serafini-2021-Effects of repetitive transcrani.pdf
PY  - 2021
T2  - PROGRESS IN NEURO-PSYCHOPHARMACOLOGY &amp; BIOLOGICAL PSYCHIATRY
TI  - Effects of repetitive transcranial magnetic stimulation on suicidal behavior: A systematic review
VL  - 105
ER  -
TY  - JOUR
AB  - **Background**: Perinatal depression is a high prevalent mental health problem with serious consequences. Evidence about effective psychological interventions in treating perinatal depression has been increasing, but it lacks a comprehensive synthesis of findings. 

**Methods**: A systematic review of systematic reviews and meta-analyses concerning the effectiveness of psychological interventions in treating perinatal depression (depression during pregnancy and the first 12 months postpartum) in adult women was conducted. The electronic databases MEDLINE (PubMed), PsycINFO, The Cochrane Library, Web of Science and Prospero were searched, on May 2020, using a combination of keywords. Data were independently extracted by two authors and a synthesis of the results was presented. Methodological quality was independently assessed by two authors, using AMSTAR-2. 

**Results**: Seven systematic reviews were included and reported, overall, the effectiveness of psychological interventions in decreasing depressive symptoms in women in the perinatal period, both short and long-term. CBT was found to be the most effective intervention, regardless of the treatment format. Limitations: Grey literature was not searched, and some studies may overlap among the included systematic reviews. These (the included reviews) were rated with low methodological quality, which weakens the evidence of the reported results. 

**Conclusions**: CBT is currently the most evidence-based psychological intervention, provided in different delivery formats (individual, group, face-to-face or Internet-based). Further studies, including systematic reviews, with other types of psychological interventions (e.g., third-wave CBT) and with higher quality are needed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-58144-036
AU  - Branquinho,
AU  - M.
AU  - de
AU  - la
AU  - Fe
AU  - Rodriguez-Munoz,
AU  - M.
AU  - Maia,
AU  - B.
AU  - R.
AU  - Marques,
AU  - M.
AU  - C.
AU  - Matos,
AU  - M.
AU  - Osma,
AU  - J.
AU  - Moreno-Peral,
AU  - P.
AU  - Conejo-Ceron,
AU  - S.
AU  - Fonseca,
AU  - A.
AU  - Vousoura,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2021.05.010
L1  - internal-pdf://1878743160/Branquinho-2021-Effectiveness of psychological.pdf
PY  - 2021
SP  - 294-306
T2  - Journal of Affective Disorders
TI  - Effectiveness of psychological interventions in the treatment of perinatal depression: A systematic review of systematic reviews and meta-analyses
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-58144-036
VL  - 291
ER  -
TY  - JOUR
AB  - **Background**: Animal-assisted interventions (AAI) are increasingly applied for people with post-traumatic stress disorder (PTSD) symptoms albeit its effectiveness is unclear. 

**Objectives**: To examine the effectiveness of AAI for treating PTSD symptoms. Method: We searched 11 major electronic databases for studies reporting quantitative data on effects of AAI for children and adults with PTSD symptoms. Of 22MODIFIER LETTER PRIME211 records identified, we included 41 studies with 1111 participants in the systematic review comprising eight controlled studies with 469 participants in the meta-analysis. We conducted random-effects meta-analyses with all controlled studies based on standardized mean differences (SMD), and calculated standardized mean change (SMC) as effect sizes for studies with a pre-post one-group design. Two independent researchers assessed the quality of the included studies using the NIH Study Quality Assessment Tools. The primary outcome was PTSD or depression symptom severity measured via a standardized measurement at pre- and post-intervention assessments. 

**Results**: There was a small but not statistically significant superiority of AAI over standard PTSD psychotherapy (SMD = -0.26, 95% CI: -0.56 to 0.04) in reducing PTSD symptom severity while AAI was superior to waitlist (SMD = -0.82, 95% CI: -1.56 to 0.08). Getting a service dog was superior to waiting for a service dog (SMD = -0.58, 95% CI: -0.88 to -0.28). AAI led to comparable effects in reducing depression as standard PTSD psychotherapy (SMD = -0.03, CI: -0.88 to 0.83). Pre-post comparisons showed large variation for the reduction in PTSD symptom severity, with SMCs ranging from -0.38 to -1.64, and for depression symptom severity, ranging from 0.01 to -2.76. Getting a service dog lowered PTSD symptoms between -0.43 and -1.10 and depression with medium effect size of -0.74. 

**Conclusions**: The results indicate that AAI are efficacious in reducing PTSD symptomatology and depression. Future studies with robust study designs and large samples are needed for valid conclusions.
AN  - WOS:000632692400001
AU  - Hediger,
AU  - K.
AU  - Wagner,
AU  - J.
AU  - Kunzi,
AU  - P.
AU  - Haefeli,
AU  - A.
AU  - Theis,
AU  - F.
AU  - Grob,
AU  - C.
AU  - Pauli,
AU  - E.
AU  - Gerger,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/20008198.2021.1879713
L1  - internal-pdf://1359809354/Hediger-2021.pdf
PY  - 2021
T2  - EUROPEAN JOURNAL OF PSYCHOTRAUMATOLOGY
TI  - Effectiveness of animal-assisted interventions for children and adults with post-traumatic stress disorder symptoms: a systematic review and meta-analysis
UR  - https://www.tandfonline.com/doi/pdf/10.1080/20008198.2021.1879713?needAccess=true
VL  - 12
ER  -
TY  - JOUR
AB  - **Importance**: Sexual and physical dating violence is prevalent among adolescents and is associated with adverse health effects. 

**Objective**: To conduct a systematic review and meta-analysis of randomized clinical trials to assess the efficacy of prevention programs for sexual and physical dating violence in adolescents. 

**Data Sources**: Search terms were combined for dating violence, adolescents, and randomized clinical trials in PsycINFO/Eric/PsycArticles, PubMed, and Web of Science databases from inception through April 2021. Study Selection: Included studies had a randomized design of any type examining the efficacy of an intervention to reduce dating violence among adolescents and provided at least 1 measure of sexual or physical dating violence. 

**Data Extraction and Synthesis**: Data extraction coded characteristics of trials, participants, and interventions and assessed risk of bias using the Revised Cochrane Collaboration Risk of Bias tool. Outcomes were pooled using a random-effects model. Subgroup and meta-regression analyses were performed to explore the target population and intervention factors associated with positive outcomes. Main Outcomes and Measures: The odds ratio (OR) was calculated for 3 different outcomes: (1) sexual dating violence, (2) physical dating violence, and (3) composite measures of sexual and physical dating violence. For each outcome, separate analyses were conducted for survivorship and perpetration scores. We also combined the scores of physical/sexual violence and perpetration/survivorship of teen dating violence into a single composite overall outcome including all studies. 

**Results**: Eighteen trials (22781 adolescents) were included. Overall, interventions were associated with reduced physical and sexual dating violence (OR, 0.78; 95% CI, 0.69-0.89; P &lt; .001). Separate analyses further indicated that this association was significant for physical violence perpetration (OR, 0.74; 95% CI, 0.59-0.92; P = .01) and survivorship (OR, 0.78; 95% CI, 0.64-0.95; P = .01). For sexual violence, the association was not statistically significant. Exploratory subgroup analyses revealed that trials targeting at-risk youth, older adolescents (age &gt;15 years), and trials involving parents in the intervention reported significantly larger effect sizes. Meta-regression analyses did not show any significant associations between intervention effect sizes and length or intensity of the programs. Publication bias was observed, but the adjusted ORs remained significant. Three studies reported iatrogenic associations. 

**Conclusions and Relevance**: Findings from this study suggest that prevention programs may be effective in reducing physical teen dating violence, but there is unclear evidence of the effect on sexual violence outcomes. Further research assessing the active ingredients of interventions, especially in the area of sexual dating violence, is warranted.
AN  - 34842911
AU  - Piolanti,
AU  - A.
AU  - Foran,
AU  - H.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1001/jamapediatrics.2021.4829
L1  - internal-pdf://2341583832/Efficacy of Interventions to Prevent Phys-2021.pdf
PY  - 2021
SP  - 29
T2  - JAMA Pediatrics
TI  - Efficacy of Interventions to Prevent Physical and Sexual Dating Violence Among Adolescents: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34842911
UR  - https://jamanetwork.com/journals/jamapediatrics/articlepdf/2786460/jamapediatrics_piolanti_2021_oi_210069_1637014787.36216.pdf
VL  - 29
ER  -
TY  - JOUR
AB  - Cognitive behavioural therapy is an effective treatment for anxiety disorders in children and young people; however, many do not benefit. Behavioural exposure appears to be the critical ingredient in the treatment of anxiety disorders. Research with adults has identified innovative strategies to optimise exposure-based treatments, yet it is not clear how to optimise the effects of exposure for children and young people. This review was a preliminary exploration of the association between potential optimisation strategies and treatment procedures and outcomes for the treatment of child anxiety symptoms/disorders. We searched Psych-Info and Medline databases using a systematic search strategy and identified 29 articles. We found preliminary evidence that some specific strategies may enhance the effects of exposure, such as dropping safety behaviours, parents and therapists discouraging avoidance, and the use of homework. However, not one significant finding was replicated by another study for the same timepoint using the same methodology. To a large degree, this lack of replication reflects a limited number of studies combined with a lack of consistency across studies around conceptualisations, methodological approaches, and outcome measures making it difficult to make meaningful comparisons between studies and draw firm conclusions. Examination is needed of a wide range of theoretically-driven potential optimisation strategies using methodologically robust, preclinical studies with children and young people. Furthermore, the methods used in future research must enable comparisons across studies and explore developmental differences in the effects of particular optimisation strategies.
AN  - WOS:000615203000001
AU  - Plaisted,
AU  - H.
AU  - Waite,
AU  - P.
AU  - Gordon,
AU  - K.
AU  - Creswell,
AU  - C.
DA  - JUN
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-020-00335-z
L1  - internal-pdf://0658928100/Plaisted-2021-Optimising Exposure for Children.pdf
PY  - 2021
SP  - 348-369
T2  - CLINICAL CHILD AND FAMILY PSYCHOLOGY REVIEW
TI  - Optimising Exposure for Children and Adolescents with Anxiety, OCD and PTSD: A Systematic Review
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131290/pdf/10567_2020_Article_335.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - This study aimed to summarize the effectiveness and safety of acupuncture in the treatment of autism spectrum disorder (ASD) through literature analysis and evaluation. 

All studies were retrieved from various databases as follows: English databases, such as PubMed, Cochrane Library, Ovid, and Web of Science, and Chinese databases, such as China National Knowledge Infrastructure (CNKI), WanFang Data (WF), and Technology Periodical Database (VIP). The Cochrane Collaboration&#039;s Bias Risk Assessment Scale was used to assess the studies&#039; risk of bias. The effects of acupuncture treatment for ASD were determined using the following indicators: childhood autism rating scale (CARS), autism behavior check list (ABC), Reynell developmental language scale (RDLS), and functional independence measure of children (WeeFIM). The risk map of bias of these studies&#039; quality and the meta-analysis results of the indicators was prepared with RevMan 5.2 software. 

Finally, 16 studies were included, five of which were in English and 11 were in Chinese. The 16 studies included 1332 patients. The CARS results for subgroup analysis were as follows: acupuncture subgroup (MD = -2.65, 95% CI (-3.22, -2.07)) and acupuncture plus massage subgroup (MD = -10.35, 95% CI (-11.34, -9.36)). The ABC results were as follows: (MD = -6.70, 95% CI (-9.10, -4.29)). The analysis results of sensory, relating, language, body and object use, and social/self-help in the subitems of ABC were as follows: sensory (MD = -2.67, 95% CI (-2.90, -2.44)), relating (MD = -3.28, 95% CI (-3.55, -3.02)), language (MD = -2.45, 95% CI (-2.73, -2.16)), body and object use (MD = -1.19, 95% CI (-1.38, -1.00)), and social/self-help (MD = -2.09, 95% CI (-2.30, -1.89)). For the analysis results of comprehension and expression ages in the subitems of RDLS, the comprehension age results were as follows: (MD = 0.08, 95% CI (-0.06, 0.22), P = 0.27). Those of expression age were as follows: (MD = 0.15, 95% CI (0.04, 0.26), P=0.009). The WeeFIM results were as follows: (MD = 3.70, 95% CI (2.38, 5.02)). 

This study suggested that acupuncture could effectively treat ASD. However, acupuncture methods and prescriptions at this stage remain heterogeneous, and acupuncture treatment operations require standardization. Studies using rigorous and standard research designs are needed to draw stronger conclusions about the advantages of using acupuncture to treat children and adolescents with ASD.
AN  - 34349825
AU  - Wang,
AU  - L.
AU  - Peng,
AU  - J.
AU  - L.
AU  - Qiao,
AU  - F.
AU  - Q.
AU  - Cheng,
AU  - W.
AU  - M.
AU  - Lin,
AU  - G.
AU  - W.
AU  - Zhang,
AU  - Y.
AU  - Gao,
AU  - T.
AU  - G.
AU  - Sun,
AU  - Y.
AU  - Y.
AU  - Tang,
AU  - W.
AU  - Z.
AU  - Wang,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1155/2021/5549849
L1  - internal-pdf://4093596386/Wang-2021-Clinical Randomized Controlled Study.pdf
PY  - 2021
SP  - 5549849
T2  - Evidence-Based Complementary &amp; Alternative Medicine: eCAM
TI  - Clinical Randomized Controlled Study of Acupuncture Treatment on Children with Autism Spectrum Disorder (ASD): A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34349825
UR  - https://downloads.hindawi.com/journals/ecam/2021/5549849.pdf
VL  - 2021
ER  -
TY  - JOUR
AB  - Over the last decades, ambulatory psychosocial interventions aimed at treating child externalized behavior problems have been developed and tested. In recent years, however, it has become clear that the reported effects of psychotherapies have been considerably overestimated due to publication bias. In addition, previous meta-analyses of psychosocial interventions aimed at treating child disruptive behaviors have not accounted for potential interaction effects among moderators. The purpose of this meta-analysis was to examine the effects of interventions while accounting for publication bias and dependencies among moderators. 

We searched electronic databases to identify randomized controlled trials targeting child externalized behavior problems treated in ambulatory settings. A total of 111 randomized controlled trials with 11,623 participating children were analyzed. Interventions targeting children with symptom severity below the clinical range demonstrated a non-significant effect (adjusted g = 0.12), while interventions targeting children with symptom severity within the clinical range demonstrated a small to moderate effect size (adjusted g = 0.38) that was sustained at follow-up (adjusted g = 0.27). We found the highest pooled effect size for individually administered treatments involving both the parent and the child (g = 1.11; no indication of publication bias). No other differences were found between delivery formats, including assisted self-help interventions. Publication bias was relatively smaller in high-quality studies. 

These findings suggest that the most effective treatment regime involves both the parent and the child, however, only when they are treated in an individual setting. Our results highlight the importance of accounting for interaction effects, publication bias and trial quality in future meta-analyses.
AN  - WOS:000605493800001
AU  - Baumel,
AU  - A.
AU  - Mathur,
AU  - N.
AU  - Pawar,
AU  - A.
AU  - Muench,
AU  - F.
DA  - JAN
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10826-020-01863-6
L1  - internal-pdf://3323618594/Baumel-2021.pdf
PY  - 2021
SP  - 65-86
T2  - JOURNAL OF CHILD AND FAMILY STUDIES
TI  - Psychosocial Interventions for Children With Externalized Behavior Problems: An Updated Meta-analysis of Moderator Effects
UR  - https://link.springer.com/content/pdf/10.1007/s10826-020-01863-6.pdf
VL  - 30
ER  -
TY  - JOUR
AB  - BAKGRUNN
Respektprogrammet er et skoleomfattende utviklingsprogram for å forebygge og redusere problematferd hos elever. Programmet beskriver hvordan en skole gjennom en innovasjonsprosess blant skolens ansatte kan utvikle og implementere tiltak basert på programmets fire prinsipp; myndig klasseledelse, at tiltakene gjennomsyrer alle deler av skolens virksomhet (bredde), at de ulike tiltakene samsvarer (konsistens) og at arbeidet følges opp (kontinuitet). Programmet retter seg mot alle skoler, og ble utviklet ved Senter for atferdsforskning (SAF, fra 2013 del av Nasjonalt senter for læringsmiljø og atferdsforskning; Læringsmiljøsenteret) ved Universitetet i Stavanger, som et bidrag til EU programmet Connect 2001. Respekt implementeres for tiden ikke aktivt. Videre utvikling og tilrettelegging av programmet avhenger av myndighetenes prioriteringer.

METODE
Litteratursøk i Mbase, Medline, Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS, SweMed ble supplert med fullstendig litteraturliste fra tiltakseier. Totalt syv artikler ble funnet å være relevante, hvorav tre evaluerer effekten av tiltaket basert på resultatene fra to longitudinelle kohort-studier.

RESULTATER
Respekt er et godt beskrevet tiltak med en god teoretisk begrunnelse og en systematisk implementeringsstrategi. Den forskningsmetodiske kvaliteten på de to effektstudiene er bra, og det ble funnet små til middels store effekter på sentrale utfallsmål basert på svar fra elever og lærere.

KONKLUSJON
Tiltaket klassifiseres på evidensnivå 4 &ndash; Tiltak med tilfredsstillende dokumentasjon på effekt.
AU  - Stormark,
AU  - K.
AU  - M.,
AU  - Mørch,
AU  - W-T.,
AU  - Martinussen,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2021
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Respekt (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/respekt-2-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - **Background and Objectives**
Cognitive performance is essential for children, given this is a critical stage of brain growth and development. This systematic review and meta-analysis aimed to ascertain if physical activity or micronutrients impact cognitive performance in children. 

**Materials and Methods**
Electronic databases (PubMed and Scopus&reg;) were searched for relevant articles published between 2012 and 2021. We emphasized randomized controlled trials (RCTs) that examined the effect of physical activity and micronutrients on cognitive performance. Data from eligible studies were gathered and evaluated using random-, fixed- or pooled-effects models with 95% confidence intervals (95% CI). 

**Results**
Physical activity appeared to improve both Mathematics (d = 1.12, 95% CI: 0.56, 1.67) and attention (d = 0.65, 95% CI: 0.15, 1.14) performances. The micronutrient vitamin B12 had a positive effect on Mathematics (d = 2.39, 95% CI: 0.79, 3.98), English (d = 5.29, 95% CI: 2.76, 7.83), Geography (d = 5.29, 95% CI: 2.76, 7.83), Science (d = 3.39, 95% CI: 2.62, 4.16) and Arts (d = 3.32, 95% CI: 1.84, 4.79). Zinc was found to positively affect English (d = 3.78, 95% CI: 0.44, 7.13), Geography (d = 4.77, 95% CI: 0.56, 8.98) and Arts (d = 2.39, CI: 0.33, 4.45). Iron positively affected Mathematics (d = 1.29, 95% CI: 0.54, 2.06), English (d = 1.29, 95% CI: 0.44, 7.13), Geography (d = 4.77, 95% CI: 0.56, 8.98) and Arts (d = 2.39, 95% CI: 0.33, 4.45). 

**Conclusions**
A more comprehensive intervention with a specific dose/level of physical activity, an increased range of cognitive performance, and a well-designed study design that accounts for dietary intake and other health outcomes are required for future studies.
AN  - 35056365
AU  - Meli,
AU  - A.
AU  - M.
AU  - Ali,
AU  - A.
AU  - Mhd
AU  - Jalil,
AU  - A.
AU  - M.
AU  - Mohd
AU  - Yusof,
AU  - H.
AU  - Tan,
AU  - M.
AU  - M.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/medicina58010057
L1  - internal-pdf://0159752664/Effects of Physical Activity and Micronut-2021.pdf
PY  - 2021
SP  - 30
T2  - Medicina
TI  - Effects of Physical Activity and Micronutrients on Cognitive Performance in Children Aged 6 to 11 Years: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=35056365
UR  - https://mdpi-res.com/d_attachment/medicina/medicina-58-00057/article_deploy/medicina-58-00057-v2.pdf
VL  - 58
ER  -
TY  - JOUR
AB  - **Purpose** The objective of this meta-analysis was to provide a quantitative synthesis of the effects of studies evaluating developmentally appropriate programs or interventions for transition-age youth with mental health disorders. 

**Methods** Studies, between January 1992 and March 2021, were included if they contained a sample population with a median age between 12 and 25 years and with a mental health disorder and described the results of health interventions addressing aspects of developmental transitions. Independent reviewers screened study texts and assessed the risk of bias. Random effects meta-analysis was used to pool data on standardized mean differences. 

**Results** Under neurodevelopmental studies (6), the effect size of interventions measuring social outcomes was 1.00 (95% CI: -0.01 to 2.00), parental stress levels was -0.10 (95% CI:-0.74 to 0.55), autism symptoms was -0.40 (95% CI: -1.58 to 0.78), and self-determination was 0.16 (95% CI:-0.38 to 0.70). Under mental illness studies (3), the effect size of interventions measuring adolescent depressive symptoms was 0.48 (95% CI: 0.01 to 0.96) and parental depressive symptoms was 1.09 (95% CI: 0.20 to 1.97). 

**Conclusions** There is no effect of interventions except on parental depressive symptoms under mental illness studies. Further research with comparable outcomes and assessments is needed.
AN  - WOS:000690851000001
AU  - Hothi,
AU  - H.
AU  - Bedard,
AU  - C.
AU  - Ceccacci,
AU  - A.
AU  - DiRezze,
AU  - B.
AU  - Kwan,
AU  - M.
AU  - Y.
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/09638288.2021.1960440
L1  - internal-pdf://1236153125/Hothi-Evaluated interventions addressing devel.pdf
PY  - 2021
SP  - 11
T2  - Disability and Rehabilitation
TI  - Evaluated interventions addressing developmental transitions for youth with mental health disorders: a meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000690851000001
UR  - https://www.tandfonline.com/doi/full/10.1080/09638288.2021.1960440
UR  - https://www.tandfonline.com/doi/pdf/10.1080/09638288.2021.1960440?needAccess=true
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Wraparound is a common method for coordinating care for children and adolescents with serious emotional disorders (SED), with nearly 100,000 youths served annually in the United States. The current systematic review and meta-analysis estimated effects on youth outcomes (symptoms, functioning, school, juvenile justice, and residential placement) and costs.

**METHOD**: A literature search identified 17 peer-reviewed and gray literature studies meeting criteria, which were coded on characteristics of sample, design, implementation, and outcomes. Random effects modeling was conducted using Comprehensive Meta-Analysis Version 3.0. Effect sizes were calculated using Hedges g. Homogeneity of effects were assessed using Q statistics.

**RESULTS**: Medium-sized effects favored Wraparound-enrolled youths for costs (g=0.391, CI=0.282-0.500, p &lt; .001), residential outcomes (g=0.413, CI=0.176-0.650, p=.001), and school functioning (g=0.397, CI=0.106-0.688, p=.007); small effects were found for mental health symptoms (g=0.358, CI=0.030-0.687, p=.033) and functioning (g=0.315, CI=0.086-0.545, p=.007). Larger effects were found for peer-reviewed studies, quasi-experimental designs, samples with a larger percentage of youths of color, and Wraparound conditions with higher fidelity.

**CONCLUSION**: Results indicate positive effects for Wraparound, especially for maintaining youths with SED in the home and community. However, many studies showed methodological weaknesses, and fidelity measurement was largely absent, suggesting a need for additional research. Nonetheless, the results should aid decisions around resource allocation, referral practices, and system partnerships among child psychiatrists and other behavioral health professionals.
AD  - Olson, Jonathan R. Drs. Olson, Pullmann, Bruns, Mr. Benjamin, and Mss. Azman and Kellogg are with the University of Washington School of Medicine, Seattle. Electronic address: jro10@uw.edu.Benjamin, Philip H. Drs. Olson, Pullmann, Bruns, Mr. Benjamin, and Mss. Azman and Kellogg are with the University of Washington School of Medicine, Seattle.Azman, Alya A. Drs. Olson, Pullmann, Bruns, Mr. Benjamin, and Mss. Azman and Kellogg are with the University of Washington School of Medicine, Seattle.Kellogg, Marianne A. Drs. Olson, Pullmann, Bruns, Mr. Benjamin, and Mss. Azman and Kellogg are with the University of Washington School of Medicine, Seattle.Pullmann, Michael D. Drs. Olson, Pullmann, Bruns, Mr. Benjamin, and Mss. Azman and Kellogg are with the University of Washington School of Medicine, Seattle.Suter, Jesse C. Dr. Suter is with the Center on Disability and Community Inclusion, University of Vermont, Burlington.Bruns, Eric J. Drs. Olson, Pullmann, Bruns, Mr. Benjamin, and Mss. Azman and Kellogg are with the University of Washington School of Medicine, Seattle.
AN  - 33785404
AU  - Olson,
AU  - J.
AU  - R.
AU  - Benjamin,
AU  - P.
AU  - H.
AU  - Azman,
AU  - A.
AU  - A.
AU  - Kellogg,
AU  - M.
AU  - A.
AU  - Pullmann,
AU  - M.
AU  - D.
AU  - Suter,
AU  - J.
AU  - C.
AU  - Bruns,
AU  - E.
AU  - J.
DA  - Mar 27
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2021.02.022
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
L1  - internal-pdf://3064866060/Olson-2021-Systematic Review and Meta-analysis.pdf
LA  - English
N1  - Using Smart Source ParsingMarOlson, Jonathan RBenjamin, Philip HAzman, Alya AKellogg, Marianne APullmann, Michael DSuter, Jesse CBruns, Eric JS0890-8567(21)00155-6
PY  - 2021
SP  - 27
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Systematic Review and Meta-analysis: Effectiveness of Wraparound Care Coordination for Children and Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33785404
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33785404&amp;id=doi:10.1016%2Fj.jaac.2021.02.022&amp;issn=0890-8567&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Systematic+Review+and+Meta-analysis%3A+Effectiveness+of+Wraparound+Care+Coordination+for+Children+and+Adolescents.&amp;aulast=Olson&amp;pid=%3Cauthor%3EOlson+JR%3C%2Fauthor%3E%3CAN%3E33785404%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.jaacap.org/article/S0890-8567(21)00155-6/pdf
VL  - 27
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: Behavioral interventions are well established treatments for children with attention-deficit/hyperactivity disorder (ADHD). However, insight into moderators of treatment outcome is limited.

**METHOD**: We conducted an individual participant data meta-analysis [IPDMA], including data of randomized controlled behavioral intervention trials for individuals with ADHD&lt;18 years. Outcomes were symptoms of ADHD, oppositional defiant disorder (ODD), and conduct disorder (CD) and impairment. Moderators investigated were symptoms and impairment severity, medication use, age, IQ, sex, socioeconomic status, and single parenthood.

**RESULTS**: For raters most proximal to treatment, small to medium sized effects of behavioral interventions were found for symptoms of ADHD, inattention, hyperactivity/impulsivity (HI), ODD and CD, and impairment. Blinded outcomes were only available for small preschool subsamples and limited measures. CD symptoms and/or diagnosis moderated outcome on ADHD, HI, ODD, and CD symptoms. Single parenthood moderated ODD outcome, ADHD severity moderated impairment outcome. Higher baseline CD or ADHD symptoms, a CD diagnosis, and single parenthood were related to worsening of symptoms in the untreated, but not in the treated group, indicating a protective rather than an ameliorative effect of behavioral interventions for these children.

**CONCLUSION**: Behavioral treatments are effective for reducing ADHD symptoms, behavioral problems, and impairment as reported by raters most proximal to treatment. Those with severe CD or ADHD symptoms, a CD diagnosis, or single parents, should be prioritized for treatment, as they may evidence worsening of symptoms in the absence of intervention.
AD  - Groenman, Annabeth P. Center for Child and Adolescent Psychiatry, University of Groningen, University Medical Center, Groningen, The Netherlands; Dutch Autism and ADHD Research Center, University of Amsterdam, The Netherlands. Electronic address: a.groenman@gmail.com.Hornstra, Rianne. Center for Child and Adolescent Psychiatry, University of Groningen, University Medical Center, Groningen, The Netherlands.Hoekstra, Pieter J. Center for Child and Adolescent Psychiatry, University of Groningen, University Medical Center, Groningen, The Netherlands.Steenhuis, Laura. Center for Child and Adolescent Psychiatry, University of Groningen, University Medical Center, Groningen, The Netherlands.Aghebati, Asma. School of Behavioral Sciences and Mental Health, Tehran Institute of Psychiatry, Iran University of Medical Sciences, Tehran, Iran.Boyer, Bianca E. University of Amsterdam, The Netherlands.Buitelaar, Jan K. Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands; Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands.Chronis-Tuscano, Andrea. University of Maryland, College Park.Daley, David. School of Medicine, Institute of Mental Health, University of Nottingham, United Kingdom.Dehkordian, Parisa. Shahid Chamran University, Ahvaz, Iran.Dvorsky, Melissa. University of California San Francisco.Franke, Nike. Liggins Institute, University of Auckland, New Zealand.DuPaul, George J. Lehigh University, Bethlehem, Pennsylvania.Gershy, Naama. School of Education, Israel and Schneider Children&#039;s Medical Center, The Hebrew University of Jerusalem, Israel.Harvey, Elizabeth. University of Massachusetts Amherst.Hennig, Timo. Universitat Hamburg, Germany.Herbert, Sharonne. Children&#039;s Hospital of Orange County, California.Langberg, Joshua. Virginia Commonwealth University, Richmond.Mautone, Jennifer A. Children&#039;s Hospital of Philadelphia, Pennsylvania.Mikami, Amori Yee. University of British Columbia, Vancouver, Canada.Pfiffner, Linda J. University of California San Francisco.Power, Thomas J. Children&#039;s Hospital of Philadelphia, Pennsylvania.Reijneveld, Sijmen A. University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.Schramm, Saytam Antonio. Inclusive Education, University of Potsdam, Germany.Schweitzer, Julie B. University of California, Davis.Sibley, Margaret H. University of Washington School of Medicine, Seattle Children&#039;s Research Institute.Sonuga-Barke, Edmund. King&#039;s College London, United Kingdom.Thompson, Catharine. School of Psychology, University of Southampton, United Kingdom.Thompson, Margaret. School of Psychology, University of Southampton, United Kingdom.Webster-Stratton, Carolyn. University of Washington, Seattle.Xie, Yuhuan. Specialty Mental Health Program of Asian Health Service, Oakland, California.Luman, Marjolein. Vrije Universiteit Amsterdam, Amsterdam, The Netherlands, and Bascule, Academic Centre for Child and Adolescent Psychiatry, Amsterdam, The Netherlands.van der Oord, Saskia. Clinical Psychology, KU Leuven, Leuven, Belgium; University of Amsterdam, Amsterdam, the Netherlands.van den Hoofdakker, Barbara J. Center for Child and Adolescent Psychiatry, University of Groningen, University Medical Center, Groningen, The Netherlands.
AN  - 33932495
AU  - Groenman,
AU  - A.
AU  - P.
AU  - Hornstra,
AU  - R.
AU  - Hoekstra,
AU  - P.
AU  - J.
AU  - Steenhuis,
AU  - L.
AU  - Aghebati,
AU  - A.
AU  - Boyer,
AU  - B.
AU  - E.
AU  - Buitelaar,
AU  - J.
AU  - K.
AU  - Chronis-Tuscano,
AU  - A.
AU  - Daley,
AU  - D.
AU  - Dehkordian,
AU  - P.
AU  - Dvorsky,
AU  - M.
AU  - Franke,
AU  - N.
AU  - DuPaul,
AU  - G.
AU  - J.
AU  - Gershy,
AU  - N.
AU  - Harvey,
AU  - E.
AU  - Hennig,
AU  - T.
AU  - Herbert,
AU  - S.
AU  - Langberg,
AU  - J.
AU  - Mautone,
AU  - J.
AU  - A.
AU  - Mikami,
AU  - A.
AU  - Y.
AU  - Pfiffner,
AU  - L.
AU  - J.
AU  - Power,
AU  - T.
AU  - J.
AU  - Reijneveld,
AU  - S.
AU  - A.
AU  - Schramm,
AU  - S.
AU  - A.
AU  - Schweitzer,
AU  - J.
AU  - B.
AU  - Sibley,
AU  - M.
AU  - H.
AU  - Sonuga-Barke,
AU  - E.
AU  - Thompson,
AU  - C.
AU  - Thompson,
AU  - M.
AU  - Webster-Stratton,
AU  - C.
AU  - Xie,
AU  - Y.
AU  - Luman,
AU  - M.
AU  - van
AU  - der
AU  - Oord,
AU  - S.
AU  - van
AU  - den
AU  - Hoofdakker,
AU  - B.
AU  - J.
DA  - Apr 28
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2021.02.024
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
L1  - internal-pdf://3833339352/Groenman-2021.pdf
LA  - English
N1  - Using Smart Source ParsingAprGroenman, Annabeth PHornstra, RianneHoekstra, Pieter JSteenhuis, LauraAghebati, AsmaBoyer, Bianca EBuitelaar, Jan KChronis-Tuscano, AndreaDaley, DavidDehkordian, ParisaDvorsky, MelissaFranke, NikeDuPaul, George JGershy, NaamaHarvey, ElizabethHennig, TimoHerbert, SharonneLangberg, JoshuaMautone, Jennifer AMikami, Amori YeePfiffner, Linda JPower, Thomas JReijneveld, Sijmen ASchramm, Saytam AntonioSchweitzer, Julie BSibley, Margaret HSonuga-Barke, EdmundThompson, CatharineThompson, MargaretWebster-Stratton, CarolynXie, YuhuanLuman, Marjoleinvan der Oord, Saskiavan den Hoofdakker, Barbara JS0890-8567(21)00233-1
PY  - 2021
SP  - 28
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - An Individual Participant Data Meta-analysis: Behavioral Treatments for Children and Adolescents With Attention-Deficit/Hyperactivity Disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33932495
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33932495&amp;id=doi:10.1016%2Fj.jaac.2021.02.024&amp;issn=0890-8567&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=An+Individual+Participant+Data+Meta-analysis%3A+Behavioral+Treatments+for+Children+and+Adolescents+With+Attention-Deficit%2FHyperactivity+Disorder.&amp;aulast=Groenman&amp;pid=%3Cauthor%3EGroenman+AP%3C%2Fauthor%3E%3CAN%3E33932495%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.jaacap.org/article/S0890-8567(21)00233-1/pdf
VL  - 28
ER  -
TY  - JOUR
AB  - OBJECTIVE: To determine the effects of interventions aimed at optimising the quantity and quality of physical education (PE) on cognition and academic performance in children and adolescents. DESIGN: A systematic review and meta-analysis. 

DATA SOURCES: Studies from electronic databases from inception to 3 January 2021 were identified.

ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Experimental studies that assessed the effect of quantity-based (ie, increasing the amount of curriculum time allocated to PE) or quality-based (ie, increasing students&#039; participation in physical activity during PE) PE interventions, or both, on changes in cognition and/or academic performance in youth (aged 5-18 years) were included. 

RESULTS: 19 trials comprising 8676 youth (46.5% girls) were included. Individual quality-based PE interventions increased cognition performance (Hedges&#039; g=0.38, 95% CI 0.15 to 0.60; I &lt;sup&gt;2&lt;/sup&gt;=83.70%), mainly in primary education settings (g=0.48, 95% CI 0.07 to 0.89; I &lt;sup&gt;2&lt;/sup&gt;=90.43%). Academic performance, principally mathematics-related skills, was also increased by quality-based PE interventions (g=0.15, 95% CI 0.06 to 0.24; I &lt;sup&gt;2&lt;/sup&gt;=41.75%). Among these interventions, teaching strategies favoured similar results, but without heterogeneity in the results (g=0.12, 95% CI 0.05 to 0.18; I &lt;sup&gt;2&lt;/sup&gt;=0%). In contrast, quantity-based PE interventions had a very small and non-significant effect on academic performance (g=0.09, 95% CI -0.05 to 0.24; Q=11.65; I &lt;sup&gt;2&lt;/sup&gt;=48.48%). Finally, there were no differences between the three PE interventions (ie, quantity, quality, and combined PE interventions) in regard to academic performance. 

CONCLUSION: Improving the quality of PE classes may improve students&#039; cognition and academic performance in children and adolescents. Importantly, allocating more time for PE does not seem to compromise this performance.
AN  - 34187782
AU  - Garcia-Hermoso,
AU  - A.
AU  - Ramirez-Velez,
AU  - R.
AU  - Lubans,
AU  - D.
AU  - R.
AU  - Izquierdo,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/bjsports-2021-104112
L1  - internal-pdf://2143399156/Garcia-Hermoso-2021.pdf
PY  - 2021
SP  - 1224-1232
T2  - British Journal of Sports Medicine
TI  - Effects of physical education interventions on cognition and academic performance outcomes in children and adolescents: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=34187782
UR  - https://bjsm.bmj.com/content/55/21/1224.long
UR  - https://bjsm.bmj.com/content/bjsports/55/21/1224.full.pdf
VL  - 55
ER  -
TY  - JOUR
AB  - **Purpose:** 
Depressive disorders are common and have a considerable impact on patients and societies. Several treatments are available, but their effects are modest and reduce the burden only to a limited extent. Preventing the onset of depressive disorders may be one option to further reduce the global disease burden. 

**Method(s):**
 We conducted a meta-analysis of randomized controlled trials in participants without a diagnosis of depression at baseline, who were assigned to a preventive psychological intervention, or a care-as-usual, or comparable control group and in which incident cases of depression at follow-up were ascertained with a diagnostic interview. 

**Result(s):**
 Our systematic searches resulted in 50 trials (14,665 participants) with relatively high quality, in high risk groups of all ages. The psychological interventions were mostly based on cognitive behavioral interventions. One year after the preventive interventions, the relative risk of developing a depressive disorder was RR = 0.81 (95% CI: 0.72-0.91), indicating that those who had received the intervention had 19% less chance to develop a depressive disorder. Given the average control event rate of 30%, twenty-one people had to participate in the intervention to prevent one depressive disorder compared to people in the control conditions. 

**Conclusion(s):**
 Prevention is a promising approach to reduce the global disease burden of depression in addition to treatments. Copyright &copy; 2020 The Author(s)
AD  - (Cuijpers, Karyotaki, Struijs) Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, Netherlands (Pineda, Llamas, Munoz) Institute for International Internet Interventions for Health (i4Health), Palo Alto University, United States (Quero) Department of Basic, Clinical Psychology and Psychobiology, Universitat Jaume I, Castellon, Spain (Quero) CIBER of Physiopathology of Obesity and Nutrition (CIBEROBN), Madrid, Spain (Karyotaki) Department of Global Health and Social Medicine, Harvard Medical School, Boston, United States (Struijs) Institute of Clinical Psychology, Leiden University, Leiden, Netherlands (Figueroa) School of Social Welfare, University of California Berkeley, United States (Furukawa) Department of Health Promotion and Human Behavior, School of Public Health, Kyoto University Graduate School of Medicine, Kyoto, JapanP. Cuijpers, Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, Van der Boechorststraat 7-9, Amsterdam 1081 BT, Netherlands. E-mail: p.cuijpers@vu.nl
AN  - 2010350335
AU  - Cuijpers,
AU  - P.
AU  - Pineda,
AU  - B.
AU  - S.
AU  - Quero,
AU  - S.
AU  - Karyotaki,
AU  - E.
AU  - Struijs,
AU  - S.
AU  - Y.
AU  - Figueroa,
AU  - C.
AU  - A.
AU  - Llamas,
AU  - J.
AU  - A.
AU  - Furukawa,
AU  - T.
AU  - A.
AU  - Munoz,
AU  - R.
AU  - F.
DA  - February
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.cpr.2020.101955
DP  - Ovid Technologies
KW  - Cognitive behavior therapy
KW  - Depression
KW  - Interpersonal psychotherapy
KW  - Major depressive disorder
KW  - Meta-analysis
KW  - Prevention
KW  - acceptance and commitment therapy
KW  - adolescent
KW  - adult
KW  - aged
KW  - child
KW  - clinical outcome
KW  - cognitive behavioral therapy
KW  - cognitive bias
KW  - comparative study
KW  - controlled study
KW  - depression/pc [Prevention]
KW  - female
KW  - follow up
KW  - global disease burden
KW  - high risk population
KW  - home care
KW  - human
KW  - incidence
KW  - major depression/pc [Prevention]
KW  - male
KW  - meta analysis
KW  - mindfulness
KW  - perinatal depression/pc [Prevention]
KW  - primary medical care
KW  - problem solving
KW  - psychotherapy
KW  - randomized controlled trial (topic)
KW  - review
KW  - systematic review
KW  - behavioral activation therapy
KW  - Cognitive Bias Modification
KW  - interpersonal therapy
L1  - internal-pdf://4047210461/Cuijpers-2021.pdf
LA  - English
M3  - Review
PY  - 2021
T2  - Clinical Psychology Review
TI  - Psychological interventions to prevent the onset of depressive disorders: A meta-analysis of randomized controlled trials
UR  - http://www.elsevier.com/locate/clinpsychrev
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010350335
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33333441&amp;id=doi:10.1016%2Fj.cpr.2020.101955&amp;issn=0272-7358&amp;isbn=&amp;volume=83&amp;issue=&amp;spage=101955&amp;pages=&amp;date=2021&amp;title=Clinical+Psychology+Review&amp;atitle=Psychological+interventions+to+prevent+the+onset+of+depressive+disorders%3A+A+meta-analysis+of+randomized+controlled+trials&amp;aulast=Cuijpers&amp;pid=%3Cauthor%3ECuijpers+P.%3C%2Fauthor%3E%3CAN%3E2010350335%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 83 (no pagination)
ER  -
TY  - JOUR
AB  - **OBJECTIVES**: Smoking is one of the biggest public health problems in the world. The World Health Organization (WHO) has declared the MPOWER package which provides a guide for tobacco control. The package includes six evidence based anti-smoking interventions. This meta-analysis study aims to assess the effectiveness of MPOWER - (M)onitor, (P)rotect, (O)ffer, (W)arn, (E)nforce, and (R)aise. In the study, &quot;smoking prevalence rate, smoking cessation rate and number of cigarettes smoked daily&quot; outputs were used in adult and adolescent age groups. 

**METHODS**: Literature search has been made with &quot;smok*, tobacco, cigarette*&quot; keywords from the databases of Medline, Web of Science, Scopus, and Cochrane-Library. Abstracts were assessed in detail according to the inclusion criteria by the research team. Quality of articles was evaluated with modified Jadad criteria. The follow-up periods of articles were determined in two groups named as short and long term periods. We used random effects model (p &lt;= 0.05) and fixed effects model (p &gt; 0.05) according to the heterogeneity test results. 

**RESULTS**: P and O interventions, which are evaluated with smoking cessation rate, increased the smoking cessation rate in adults by 39% in the longest follow-up period - RR: 1.39 (1.23-1.57). However, it was determined that the interventions were not effective on smoking cessation rate in adolescents - RR: 1.13 (0.90-1.42). Nicotine replacement therapy (NRT) was the most effective intervention for smoking cessation rate in adults. W interventions, which are evaluated with smoking prevalence rate, decreased the smoking prevalence rate in adults by 13% in the longest follow-up period - OR: 0.87 (0.82-0.92). P, W and E interventions, which are evaluated with smoking prevalence rate, decreased the smoking prevalence rate in adolescents by 26% in the longest follow-up period - OR: 0.74 (0.68-0.80). 

**CONCLUSIONS**: MPOWER interventions affect smoking prevalence rate, smoking cessation rate and number of cigarettes smoked daily in different age groups. Well-controlled, well-planned and cost-effective anti-smoking interventions have great importance for public health protection.
AN  - 34245554
AU  - Unal,
AU  - E.
AU  - Metintas,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.21101/cejph.a6350
L1  - internal-pdf://0073789242/Unal-2021-Effectiveness of anti-smoking interv.pdf
PY  - 2021
SP  - 134-142
T2  - Central European Journal of Public Health
TI  - Effectiveness of anti-smoking interventions towards community: a meta-analysis study
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34245554
VL  - 29
ER  -
TY  - JOUR
AB  - Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that has gained relevance in recent years as an alternative treatment for neuropsychiatric conditions. The aim of this study is to conduct a systematic review of the use of tDCS in Autism Spectrum Disorder (ASD). Both electronic and manual searches were conducted to identify studies published in peer-reviewed scientific journals addressing the use of tDCS in ASD population. A total of 16 studies fulfilled the criteria to be included in the review. Studies were conducted both in child and adult population. Anodal stimulation on the left dorsolateral prefrontal cortex was the most commonly chosen methodology. Outcomes addressed ASD symptoms and neuropsychological functions. Meta-analytic synthesis identified improvements in social, health, and behavioral problem domains of the Autism Treatment Evaluation Checklist. Limitations included high heterogeneity in the methodology and low-efficacy study designs (pre-post and single-case studies). Recent controlled trials shed promising results for the use of tDCS in ASD. A standardized stimulation protocol and a consensus in the measures used in the evaluation of the efficacy are imperative. Copyright &copy; 2021
AD  - (Garcia-Gonzalez, Lugo-Marin, Setien-Ramos, Gisbert-Gustemps, Ramos-Quiroga) Department of Psychiatry, Hospital Universitari Vall d&#039;Hebron, Barcelona, Catalonia, Spain (Setien-Ramos, Arteaga-Henriquez, Ramos-Quiroga) Group of Psychiatry, Mental Health and Addictions, Vall d&#039;Hebron Research Institute (VHIR), Barcelona, Catalonia, Spain (Gisbert-Gustemps, Ramos-Quiroga) Department of Psychiatry and Legal Medicine, Universitat Autonoma de Barcelona, Barcelona, Spain (Diez-Villoria) Centro de Atencion Integral al Autismo-InFoAutismo, INICO-Instituto Universitario de Integracion en la Comunidad, University of Salamanca, Salamanca, Spain (Ramos-Quiroga) Psychiatric Genetics Unit, Vall d&#039;Hebron Research Institute, Universitat Autonoma de Barcelona, Barcelona, Spain (Ramos-Quiroga) Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, SpainJ.A. Ramos-Quiroga, Department of Psychiatry, Hospital Universitari Vall d&#039;Hebron, Barcelona, Catalonia, Spain. E-mail: jaramos@vhebron.net
AN  - 2011499958
AU  - Garcia-Gonzalez,
AU  - S.
AU  - Lugo-Marin,
AU  - J.
AU  - Setien-Ramos,
AU  - I.
AU  - Gisbert-Gustemps,
AU  - L.
AU  - Arteaga-Henriquez,
AU  - G.
AU  - Diez-Villoria,
AU  - E.
AU  - Ramos-Quiroga,
AU  - J.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.euroneuro.2021.02.017
DP  - Ovid Technologies
KW  - Autism Spectrum Disorder
KW  - Systematic review
KW  - Transcranial direct current stimulation
KW  - adult
KW  - article
KW  - autism
KW  - checklist
KW  - child
KW  - comparative effectiveness
KW  - consensus
KW  - controlled clinical trial (topic)
KW  - controlled study
KW  - dorsolateral prefrontal cortex
KW  - female
KW  - human
KW  - male
KW  - problem behavior
KW  - single-case study
KW  - synthesis
L1  - internal-pdf://3827108362/Garcia-Gonzalez-2021.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2021
PY  - 2021
T2  - European Neuropsychopharmacology.
TI  - Transcranial direct current stimulation in Autism Spectrum Disorder: A systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/euroneuro
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2011499958
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33773886&amp;id=doi:10.1016%2Fj.euroneuro.2021.02.017&amp;issn=0924-977X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=European+Neuropsychopharmacology&amp;atitle=Transcranial+direct+current+stimulation+in+Autism+Spectrum+Disorder%3A+A+systematic+review+and+meta-analysis&amp;aulast=Garcia-Gonzalez&amp;pid=%3Cauthor%3EGarcia-Gonzalez+S.%3C%2Fauthor%3E%3CAN%3E2011499958%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **BACKGROUND**: This systematic review and meta-analysis assesses the efficacy of regular, moderate to vigorous physical activity (MVPA) for attention deficit hyperactivity disorder (ADHD) in children and adolescents in randomized controlled trials (RCTs).

**METHODS**: RCTs including children and adolescents with clinically diagnosed ADHD, implementing regular MVPA, and assessing ADHD core-symptoms on a valid rating scale post-intervention (primary outcome) were included. Outcomes were pooled through random-effects meta-analysis. Prospero registration: CRD42019142166.

**RESULTS**: MVPA had a small effect on total ADHD core symptoms (n = 11; g = -0.33; 95% CI [-0.63; -0.02]; p = .037).

**CONCLUSIONS**: MVPA could serve as an alternative treatment for ADHD. New RCTs are necessary to increase the understanding of the effect regarding frequency, intensity, type of MVPA interventions, and differential effects on age groups.
AD  - Seiffer, Britta. University of Tuebingen, Department of Clinical Psychology and Psychotherapy, Tuebingen, Germany.Seiffer, Britta. University of Tuebingen, Department of Education &amp; Health Research, Tuebingen, Germany.Hautzinger, Martin. University of Tuebingen, Department of Clinical Psychology and Psychotherapy, Tuebingen, Germany.Ulrich, Rolf. University of Tuebingen, Department of Cognition and Perception, Tuebingen, Germany.Wolf, Sebastian. University of Tuebingen, Department of Clinical Psychology and Psychotherapy, Tuebingen, Germany.Wolf, Sebastian. University of Tuebingen, Department of Education &amp; Health Research, Tuebingen, Germany.
AN  - 34041952
AU  - Seiffer,
AU  - B.
AU  - Hautzinger,
AU  - M.
AU  - Ulrich,
AU  - R.
AU  - Wolf,
AU  - S.
DA  - May 27
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/10870547211017982
DP  - Ovid Technologies
J2  - J Atten Disord
L1  - internal-pdf://2990884400/Seiffer-2021.pdf
LA  - English
N1  - Seiffer, BrittaHautzinger, MartinUlrich, RolfWolf, Sebastian
PY  - 2021
SP  - 10870547211017982
T2  - Journal of Attention Disorders
TI  - The Efficacy of Physical Activity for Children with Attention Deficit Hyperactivity Disorder: A Meta-Analysis of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34041952
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:34041952&amp;id=doi:10.1177%2F10870547211017982&amp;issn=1087-0547&amp;isbn=&amp;volume=&amp;issue=&amp;spage=10870547211017982&amp;pages=10870547211017982&amp;date=2021&amp;title=Journal+of+Attention+Disorders&amp;atitle=The+Efficacy+of+Physical+Activity+for+Children+with+Attention+Deficit+Hyperactivity+Disorder%3A+A+Meta-Analysis+of+Randomized+Controlled+Trials.&amp;aulast=Seiffer&amp;pid=%3Cauthor%3ESeiffer+B%3C%2Fauthor%3E%3CAN%3E34041952%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/10870547211017982
ER  -
TY  - JOUR
AB  - **Purpose**: Although the number of school-based education programs for child sexual abuse (CSA) prevention has recently increased in China, little is known about their effectiveness. This meta-analysis aimed to examine the effectiveness of school-based CSA prevention programs on improving children&#039;s knowledge and skills, which can prevent them from being sexually abused. 

**Method**: Systematic searches were conducted based on five English-language databases (PubMed, Web of Science, ScienceDirect, MEDLINE, and PsycINFO) and three Chinese databases (CNKI, Wan Fang Data, and CQVIP). Seven studies with 2,593 participants finally met the quality criteria of this review, and the meta-analysis was conducted using a random effect model. Results: The overall effect sizes of school-based CSA prevention education showed a significant improvement in children&#039;s knowledge (d = 2.53, 95% CI [2.03, 3.04]) and skills (d = 2.00, 95% CI [1.39, 2.60]). Programs instructed by researchers were more effective than those instructed by teachers, and preschoolers had a larger increase in both knowledge and skills than elementary and middle school students. Discussion: 

This study provides empirical evidence for further implementation of school-based CSA prevention programs, especially under the guidance of experienced researchers and conducted for students at an early age.
AN  - WOS:000672959800001
AU  - Zhang,
AU  - H.
AU  - P.
AU  - Shi,
AU  - R.
AU  - Li,
AU  - Y.
AU  - L.
AU  - Wang,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/10497315211022827
L1  - internal-pdf://3883005409/Zhang-Effectiveness of School-Based Child Sexu.pdf
PY  - 2021
SP  - 13
T2  - Research on Social Work Practice
TI  - Effectiveness of School-Based Child Sexual Abuse Prevention Programs in China: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000672959800001
UR  - https://journals.sagepub.com/doi/10.1177/10497315211022827
UR  - https://journals.sagepub.com/doi/pdf/10.1177/10497315211022827
ER  -
TY  - JOUR
AB  - **Objective** To assess effects of treatment against a hypothesized neuroinflammation in children with symptoms corresponding to the research condition Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) which is not included in current diagnostic systems. 

**Methods** Systematic literature searches were performed (1998 to June 2020) in PubMed, Embase, the Cochrane Library, CINAHL, PsycInfo, and HTA databases. Inclusion criteria: Patients (P) were children (&lt;18 years) with PANS; intervention (I)/comparison (C) was use of, versus no use of, anti-inflammatory, antibacterial or immunomodulating treatments; outcomes (O) were health-related quality of life (HRQL), level of functioning, symptom change, and complications. 

**Results** Four randomised controlled trials (RCTs) and three non-RCTs, including 23 to 98 patients, fulfilled the PICO. HRQL was not investigated in any study. Regarding level of functioning, two RCTs investigated antibiotics (penicillin V, azithromycin) and one RCT investigated immunomodulating treatments (intravenous immunoglobulins (IVIG), plasma exchange). Regarding symptoms, two non-RCTs investigated anti-inflammatory treatment (cyclooxygenase (COX) inhibitors, corticosteroids), two RCTs and one non-RCT investigated antibiotics (penicillin V, azithromycin), and two RCTs investigated immunomodulating treatments (IVIG, plasma exchange). Complications, reported in five studies, were consistent with those listed in the summary of products characteristics (SPC). All studies were assessed to have some or major problems regarding directness, the absence of an established diagnosis contributing to clinical diversity in the studied populations. All studies were assessed to have major risk of bias, including selection and detection biases. Due to clinical and methodological diversity, meta-analyses were not performed. 

**Conclusion** This systematic review reveals very low certainty of evidence of beneficial effects, and moderate certainty of evidence of adverse effects, of anti-inflammatory, antibacterial or immunomodulating treatments in patients with symptoms corresponding to the research condition PANS. Available evidence neither supports nor excludes potential beneficial effects, but supports that such treatment can result in adverse effects. Copyright &copy; 2021 Johnson et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AN  - 2013373785
AU  - Johnson,
AU  - M.
AU  - Ehlers,
AU  - S.
AU  - Fernell,
AU  - E.
AU  - Hajjari,
AU  - P.
AU  - Wartenberg,
AU  - C.
AU  - Wallerstedt,
AU  - S.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0253844
L1  - internal-pdf://1560915029/Johnson-2021-Anti-inflammatory, antibacterial.pdf
PY  - 2021
T2  - PLoS ONE [Electronic Resource]
TI  - Anti-inflammatory, antibacterial and immunomodulatory treatment in children with symptoms corresponding to the research condition PANS (Pediatric Acuteonset Neuropsychiatric Syndrome): A systematic review
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0253844&amp;type=printable
UR  - https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0253844/1/pone.0253844.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&amp;X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210825%2Fauto%2Fstorage%2Fgoog4_request&amp;X-Goog-Date=20210825T075838Z&amp;X-Goog-Expires=86400&amp;X-Goog-SignedHeaders=host&amp;X-Goog-Signature=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
VL  - 16 (7 July) (no pagination)
ER  -
TY  - JOUR
AB  - **Background **
Stuttering, or stammering as it is referred to in some countries, affects a child&#039;s ability to speak fluently. It is a common communication disorder, affecting 11% of children by four years of age. Stuttering can be characterized by sound, part word or whole word repetitions, sound prolongations, or blocking of sounds or airflow. Moments of stuttering can also be accompanied by non‐verbal behaviours, including visible tension in the speaker&#039;s face, eye blinks or head nods. Stuttering can also negatively affect behavioural, social and emotional functioning. 

**Objectives **
Primary objective 
To assess the immediate and long‐term effects of non‐pharmacological interventions for stuttering on speech outcomes, communication attitudes, quality of life and potential adverse effects in children aged six years and younger. 

Secondary objective 
To describe the relationship between intervention effects and participant characteristics (i.e. child age, IQ, severity, sex and time since stuttering onset) at pretest. Search methods We searched CENTRAL, MEDLINE, Embase, PsycINFO, nine other databases and two trial registers on 16 September 2020, and Open Grey on 20 October 2020. There were no limits in regards to language, year of publication or type of publication. We also searched the reference lists of included studies and requested data on unpublished trials from authors of published studies. We handsearched conference proceedings and programmes from relevant conferences. 

**Selection criteria** 
We included randomized controlled trials (RCTs) and quasi‐RCTs that assessed non‐pharmacological interventions for stuttering in young children aged six years and younger. Eligible comparators were no intervention, wait list or management as usual. Data collection and analysis We used standard methodological procedures expected by Cochrane. 

**Main results** 
We identified four eligible RCTs, all of which compared the Lidcombe Program to a wait‐list control group. In total, 151 children aged between two and six years participated in the four included studies. In the Lidcombe Program, the parent and their child visit a speech and language therapist (SLT) in a clinic. One study conducted clinic visits by telephone. In each clinic visit, parents were taught how to conduct treatment at home. Two studies took place in Australia, one in New Zealand and one in Germany. 

Two studies were conducted for nine months, one for 16 weeks and one for 12 weeks. The frequency of clinic visits and practice sessions at home varied within the programme. One study was partially funded by the Rotary Club, Wiesbaden, Germany; and one was funded by the National Health and Medical Research Council of Australia. One study did not report funding sources and another reported that they did not receive any funding for the trial. All four studies reported the outcome of stuttering frequency. One study also reported on speech efficiency, defined as articulation rate. No studies reported the other predetermined outcomes of this review, namely stuttering severity; communication attitudes; emotional, cognitive or psychosocial domains; or adverse effects. The Lidcombe Program resulted in a lower stuttering frequency percentage syllables stuttered (% SS) than a wait‐list control group at post‐test, 12 weeks, 16 weeks and nine months postrandomization (mean difference (MD) &minus;2.16, 95% confidence interval (CI) &minus;3.48 to &minus;0.84, 4 studies, 151 participants; P = 0.001; very low‐certainty evidence). 

However, as the Lidcombe Program is designed to take one to two years to complete, none of the participants in these studies had finished the complete intervention programme at any of the data collection points. We assessed stuttering frequency to have a high risk of overall bias due to high risk of bias in at least one domain within three of four included studies, and to have some concern of overall bias in the fourth, due to some concern in at least one domain. We found moderate‐certainty evidence from one study showing that the Lidcombe Program may i crease speech efficiency in young children. 

Only one study reported outcomes at long‐term follow‐up. The long‐term effect of intervention could not be summarized, as the results for most of the children in the control group were missing. However, a within‐group comparison was performed between the mean % SS at randomization and the mean % SS at the time of extended follow‐up, and showed a significant reduction in frequency of stuttering. 

**Authors&#039; conclusions**
This systematic review indicates that the Lidcombe Program may result in lower stuttering frequency and higher speech efficiency than a wait‐list control group in children aged up to six years at post‐test. However, these results should be interpreted with caution due to the very low and moderate certainty of the evidence and the high risk of bias identified in the included studies. 

Thus, there is a need for further studies from independent researchers, to evaluate the immediate and long‐term effects of other non‐pharmacological interventions for stuttering compared to no intervention or a wait‐list control group. Plain language summary Medicine‐free treatment for stuttering in children aged six years and younger What was the aim of this review? The aim of this review was to find out if medicine‐free treatment for stuttering can improve speech fluency, children&#039;s communication attitudes and the impact on the child&#039;s quality of life, and potential harmful effects in children aged six years and younger, both in the short‐ and long‐term. We collected and analyzed all relevant studies to answer this question and found four studies. Key messages The Lidcombe Program may result in lower stuttering frequency and higher speech efficiency (i.e. number of words or syllables spoken per minute) for young children after receiving the amount of treatment included in the studies. We do not yet know the impact of the programme delivered in its entirety, as no study reported outcomes for children who had completed the programme, which is designed to last for one to two years. 

Only one study reported how treatment worked in the long run, but the effect of treatment could not be summarized, as the results for most children in the control group were missing. We require more high‐quality studies assessing stuttering treatments for young children, including studies that report on a broader range of outcomes and that assess treatments other than the Lidcombe Program. 

What did the review study? Stuttering, or stammering as it is sometimes called, is a common communication disorder, that usually begins when children are between two and four years of age. Stuttering can be characterized by repetitions of individual speech sounds, parts of words or whole words; involuntary lengthening of speech sounds; or speech blockages. Moments of stuttering can also be accompanied by visible tension in the speaker&#039;s face or voice, eye blinks or head nods. Stuttering can have a negative effect on how people feel about themselves and how they live their lives. Therefore, it is important to identify effective treatments for stuttering in young children to reduce the chance that they will experience these negative effects. 

What were the main results of the review? We found four studies, all of which compared young children who received the Lidcombe Program to young children on a wait‐list.  In three studies, the children on the wait‐list did not receive any treatment until after the study was finished. In the fourth, the children on the wait‐list could receive treatment from their local speech language therapist (SLT) if they wanted to. At the end of the study, parents of seven children (35%) in the control group reported their child had received some treatment, either the Lidcombe Program or another treatment programme called &quot;Easy Does It&quot;, while on the wait‐list. 

There were 151 children aged between two and six years in the four studies. In the Lidcombe Program, an SLT conducted clinic visits with the child and parent in person in a clinic or spoke to them by telephone During these visits, parents were taught to conduct treatment at home during 10‐ to 15‐minute daily practice sessions. Two studies were conducted in Australia, one in New Zealand and one in Germany. Two studies were conducted for nine months, one for 16 weeks and one for 12 weeks. One study was partially funded by the Rotary Club, Wiesbaden, Germany; and one was funded by the National Health and Medical Research Council of Australia. One study did not report any funding sources and another reported that they did not receive any funding for the trial. All four studies reported the effects of treatment on stuttering frequency. 

One study also reported on speech efficiency. We found no studies that looked at the effects of treatments for stuttering on stuttering severity; communication attitudes; emotional (how a child recognizes, expresses, and manages feelings), cognitive (how a child thinks, explores and works problems out) or psychosocial (how a child&#039;s individual needs link to the needs or demands of society) development; or side effects. The included studies suggest that the Lidcombe Program may reduce stuttering frequency in young children compared to a wait‐list control group (very low‐quality evidence). One study also reported that the Lidcombe Program may increase speech efficiency in young children compared to a wait‐list control group (moderate‐quality evidence). 

Only one study followed the children up to five years after treatment started, and at that time the results for most of the children in the control group were missing. Therefore, we do not know if the benefits of the treatment lasted over time. How up‐to‐date was this review? We searched for studies that had been published up to 16 September 2020. One additional database was searched on 20 October 2020. 

How reliable was the evidence generated by this review? The quality of the results related to stuttering frequency was very low and the results related to speech efficiency was moderate. This means that we are uncertain that the treatment effect would stay the same if we added more studies to the review. More studies comparing different treatments for stuttering to a wait‐list control group are needed to know the effect of treatment for stuttering with greater certainty.
AN  - CD013489
AU  - Sjøstrand,
AU  - Å
AU  - Kefalianos,
AU  - E.
AU  - Hofslundsengen,
AU  - H.
AU  - Guttormsen,
AU  - L.
AU  - S.
AU  - Kirmess,
AU  - M.
AU  - Lervåg,
AU  - A.
AU  - Hulme,
AU  - C.
AU  - Bottegaard
AU  - Næss,
AU  - K.
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1002/14651858.CD013489.pub2
N1  - [Developmental, Psychosocial and Learning Problems]
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - Non‐pharmacological interventions for stuttering in children six years and younger
UR  - http://dx.doi.org/10.1002/14651858.CD013489.pub2
ER  -
TY  - JOUR
AB  - **INTRODUCTION**: The omega-3 long-chain polyunsaturated fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are important for brain development and cognitive performance. Because they are semi-essential fatty acids, they must be obtained from food. However, the dietary reference intakes of DHA and EPA have not yet been established. In women, a low DHA and/or EPA serum level during pregnancy or breastfeeding might negatively affect their children. For this study, we conducted a systematic review and meta-analysis of randomized control trials on the association between the consumption of fish oil supplements in pregnant and/or breastfeeding women and the cognitive performance of their children.

**METHODS**: The PubMed, Embase, and Central literature databases were systematically searched. We included and extracted relevant studies in duplicate and assessed study quality. Cognitive outcomes were grouped according to published criteria and according to time elapsed after the intervention. We performed fixed-effects meta-analyses for each cognitive outcome and for birth weight. We assessed potential confounding with meta-regressions and sensitivity analyses.

**RESULTS**: A total of 11 trials were included. No significant association was found between DHA/EPA supplementation and any of the assessed cognitive parameters or birth weight.

**DISCUSSION**: Our results confirm previous reviews on the studied topic. Reasons for inconclusive results may be small sample sizes for each assessed category, questionable quality of included studies, and the difficulty of reliably measuring cognitive performance in small children. Blood levels of omega-3 long-chain polyunsaturated fatty acids were mostly not comparable. Furthermore, the influence of genetic and environmental factors could not be assessed. Studies in this field should address such shortcomings.
AD  - Lehner, A. Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.Staub, K. Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.Staub, K. Zurich Center for Integrative Human Physiology, University of Zurich, Switzerland.Aldakak, L. Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.Eppenberger, P. Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.Ruhli, F. Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.Ruhli, F. Zurich Center for Integrative Human Physiology, University of Zurich, Switzerland.Martin, Robert D. Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.Martin, Robert D. Integrative Research Center, The Field Museum, Chicago, Illinois, USA.Bender, N. Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.
AN  - 32918470
AU  - Lehner,
AU  - A.
AU  - Staub,
AU  - K.
AU  - Aldakak,
AU  - L.
AU  - Eppenberger,
AU  - P.
AU  - Ruhli,
AU  - F.
AU  - Martin,
AU  - R.
AU  - D.
AU  - Bender,
AU  - N.
DA  - 04 07
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/nutrit/nuaa060
DP  - Ovid Technologies
J2  - Nutr Rev
KW  - Child
KW  - Child, Preschool
KW  - *Cognition/de [Drug Effects]
KW  - *Dietary Supplements
KW  - *Docosahexaenoic Acids/ad [Administration &amp; Dosage]
KW  - Docosahexaenoic Acids/pd [Pharmacology]
KW  - *Eicosapentaenoic Acid/ad [Administration &amp; Dosage]
KW  - Eicosapentaenoic Acid/pd [Pharmacology]
KW  - Female
KW  - Humans
KW  - Infant
KW  - Pregnancy
KW  - 25167-62-8 (Docosahexaenoic Acids)
KW  - AAN7QOV9EA (Eicosapentaenoic Acid)
L1  - internal-pdf://1277232963/Lehner-2021.pdf
LA  - English
M3  - Meta-Analysis
Research Support, Non-U.S. Gov&#039;t
Systematic Review
N1  - Lehner, AStaub, KAldakak, LEppenberger, PRuhli, FMartin, Robert DBender, N
PY  - 2021
SP  - 585-598
T2  - Nutrition Reviews
TI  - Impact of omega-3 fatty acid DHA and EPA supplementation in pregnant or breast-feeding women on cognitive performance of children: systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=32918470
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32918470&amp;id=doi:10.1093%2Fnutrit%2Fnuaa060&amp;issn=0029-6643&amp;isbn=&amp;volume=79&amp;issue=5&amp;spage=585&amp;pages=585-598&amp;date=2021&amp;title=Nutrition+Reviews&amp;atitle=Impact+of+omega-3+fatty+acid+DHA+and+EPA+supplementation+in+pregnant+or+breast-feeding+women+on+cognitive+performance+of+children%3A+systematic+review+and+meta-analysis.&amp;aulast=Lehner&amp;pid=%3Cauthor%3ELehner+A%3C%2Fauthor%3E%3CAN%3E32918470%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://academic.oup.com/nutritionreviews/article-abstract/79/5/585/5904386?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/nuaa060.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtEwggLNBgkqhkiG9w0BBwagggK-MIICugIBADCCArMGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMHSvNdSGUOmo7NlH0AgEQgIIChFSH5EvevVhY41x1ivpWTy_PQUxubTDzq3V_yGhwACiLCezkUfTgq_ZUi1tDc7Kml1oFXOupkC_AYgCIFaJ_BZyTMNPr-4YtlsFS3DY1SfRp9a2n2oCkEBy7fBJjtgo9k9QDqKP0JXgnGmdOFDRtP0mwJiaomHMzSIdjt99KfD8ITWx3WEs9fuCyzijfGJEgwxxg6M7HUy0puOo5ZzW_dUtC-usNaUeobX_TDTyMLGvij6IQ9oCXPt84jvDhSWN-cwf6fX4YFzfDLnAUIujQoSiPUlv0mLTe_vvEq3PXo8SLOr78dmLZMR6mrlPV9OWzUvWBqCe628OxBMIrKNK3b4k5P7G_A8hlLa3HeCq_NjFIl2RuX-QMH3XDOI8H9mDZAQtP8Z9hPtRSW_Z3pHavxqaRJqGZ2WCPQDoDDURbSiiw4eqqyGroOz96toh5l02-IAPjShoZ9S_s0PGTNQZYdE-LaQDUI6mrhswVL-d0uSXdTPVMS2brfKH4Hgrt_H8PYf7_c2ii0mDCXFNdlV9tiQmYmT1lNC3A9VIj0OPtP3BdX5UUI1yHZ2EoRWlW7GbQ5AZd4tSBDH8y5ZPa07HWfLrfzxCSkqHs7vdVJeOo9oyYx7Iwb9P8NhnGaCNm1qLeY-TeCN0-EbT2swYbwftQNFLqp60Hpo861VTbPzsYPRdzLS9dW9pXSyKuZkoNcvfwmzOizm1Ipq_1gPMNGhw6TuWl0c1ibl33pcFSx1rzkbeiHDQ03HJLSBy6egQZ-m-tLjw8JW4cyiXKuu_DTVNVL9eA1zq8QiyIWvQnDYEIs66YHO_fjD90EG7RgCqV-FHDb1TcAUpJxRyNnuo3R_guybsEwUFg
VL  - 79
ER  -
TY  - JOUR
AB  - Childhood attention-deficit/hyperactivity disorder (ADHD) is a risk factor for the development of substance abuse and substance use disorders (SUD) in adolescence and (early) adulthood. ADHD and SUD also frequently co-occur in treatment-seeking adolescents, which complicates diagnosis and treatment, and is associated with poor treatment outcomes. 

In this study, we provide a systematic review of controlled studies on the effectiveness of pharmacological, psychosocial, and complementary treatments of ADHD in adolescents with and without comorbid SUD. In addition, we review the longitudinal association between pharmacotherapy for childhood ADHD and the development of SUD in adolescence and early adulthood. We conducted a systematic review of the research literature published since 2000 using Medline, PsycINFO, and the Cochrane Database of Systematic Reviews databases to select randomized clinical trials, observational studies, and meta-analyses. 

The quality of the evidence from each study was rated using the SIGN grading system. Based on the limited evidence available, strong clinical recommendations are not justified, but provisionally, we conclude that stimulant treatment in children with ADHD may prevent the development of SUD in adolescence or young adulthood, that high-dose stimulant treatment could be an effective treatment for adolescents with ADHD and SUD comorbidity, that cognitive behavior therapy might have a small beneficial effect in these patients, and that alternative treatments are probably not effective. 

More studies are needed to draw definitive conclusions that will allow for strong clinical recommendations.
AN  - 34501355
AU  - Ozgen,
AU  - H.
AU  - Spijkerman,
AU  - R.
AU  - Noack,
AU  - M.
AU  - Holtmann,
AU  - M.
AU  - Schellekens,
AU  - A.
AU  - Dalsgaard,
AU  - S.
AU  - van
AU  - den
AU  - Brink,
AU  - W.
AU  - Hendriks,
AU  - V.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/jcm10173908
L1  - internal-pdf://2973904537/Ozgen-2021-Treatment of Adolescents with Concu.pdf
PY  - 2021
SP  - 30
T2  - Journal of Clinical Medicine
TI  - Treatment of Adolescents with Concurrent Substance Use Disorder and Attention-Deficit/Hyperactivity Disorder: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34501355
UR  - https://mdpi-res.com/d_attachment/jcm/jcm-10-03908/article_deploy/jcm-10-03908-v2.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - Anxiety disorders are one of the most prevalent disorders in youth and can have substantial negative impacts when left untreated. Parent-child interaction therapy (PCIT) is an evidence-based approach for treating externalizing problems within youth. However, PCIT may have a unique advantage for treating anxiety symptoms and disorders because of its accessibility for younger children that may be too young to benefit from traditional cognitive behavioral therapy. The parent training aspect of PCIT could also give added support to parents by teaching them more effective ways to cope with their child&#039;s anxiety symptoms. 

The current meta-analysis aimed to determine the efficacy of PCIT and adaptations to PCIT in reducing anxious symptomology in youth. PsycINFO and PubMed were searched for relevant articles and yielded 15 articles that met inclusion criteria. Statistical analyses showed that PCIT overall was significantly more effective at reducing anxious symptomology than control groups. In addition, participants who had comorbid diagnoses in addition to anxiety had comparable reductions in anxiety as participants who did not have comorbid diagnoses. Participants with subclinical anxiety levels also demonstrated significant reductions in anxiety symptoms overall, suggesting that PCIT may be a promising early intervention for halting the progression toward disorder-threshold anxiety. 

Overall, this metaanalysis provides preliminary evidence that PCIT is an effective intervention for in ameliorating anxiety symptoms in youth.
AN  - WOS:000661282600009
AU  - Phillips,
AU  - S.
AU  - Mychailyszyn,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.childyouth.2021.105986
L1  - internal-pdf://3214723833/Phillips-2021-A review of Parent-Child Interac.pdf
PY  - 2021
SP  - 11
T2  - Children and Youth Services Review
TI  - A review of Parent-Child Interaction Therapy (PCIT): Applications for youth anxiety
UR  - &lt;Go to ISI&gt;://WOS:000661282600009
VL  - 125
ER  -
TY  - JOUR
AB  - While strong inhibitory control is critical for health and wellbeing, there are no broadly applicable effective behavioural interventions that enhance it. This meta-analysis examined the neurocognitive rationale for combined physical and cognitive training and synthesised the rapidly growing body of evidence examining combined paradigms to enhance inhibitory control. Across the research to date, there was a small positive effect (n studies = 16, n participants = 832) of combined training on improving inhibitory control. Sub-group analyses showed small-moderate positive effects when the physical component of the combined training was moderately intense, as opposed to low or vigorous intensities; moderate positive effects were found in older adults, as compared to adolescents and adults; and healthy individuals and those with vascular cognitive impairment, as compared to ADHD, ASD, mild cognitive impairment and cancer survivors. This is the first meta-analysis to provide evidence that combined physical, specifically when moderately intense, and cognitive training has the capacity to improve inhibitory control, particularly when delivered to healthy individuals and those experiencing age-related decline.
AN  - 34256070
AU  - Dhir,
AU  - S.
AU  - Teo,
AU  - W.
AU  - P.
AU  - Chamberlain,
AU  - S.
AU  - R.
AU  - Tyler,
AU  - K.
AU  - Yucel,
AU  - M.
AU  - Segrave,
AU  - R.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.neubiorev.2021.07.008
L1  - internal-pdf://2855436090/Dhir-2021-The Effects of Combined Physical and.pdf
PY  - 2021
SP  - 735-748
T2  - Neuroscience &amp; Biobehavioral Reviews
TI  - The Effects of Combined Physical and Cognitive Training on Inhibitory Control: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34256070
VL  - 128
ER  -
TY  - JOUR
AB  - **Background:** 
Iron deficiency and developmental delay are common in African children. While experimental studies indicate an important role of iron in brain development, effects of iron on child development remain unclear. We aimed to evaluate the effects of iron supplementation or fortification on neurobehavioural outcomes in African children and further summarise these effects in children living in non-African countries for comparison. 

**Methods:** 
We searched PubMed, EMBASE, PsycINFO, Scopus and Cochrane Library for studies published up to 22nd October 2021. We included randomised controlled trials (RCTs) evaluating effects of iron supplementation or fortification on neurobehavioural outcomes in children. Due to heterogeneity in study methods, we analysed all studies qualitatively and in secondary analyses only seven RCTs with 11 arms were meta-analysed.

**Results:** 
We identified 2231 studies and included 35 studies (n=9988) in the systematic review. Only five studies (n=1294) included African children while 30 (n=8694) included children living in non-African countries. Of the five African studies, two (n=647) reported beneficial effects of iron supplementation on neurobehavioural outcomes in anaemic children, while three (n=647) found no beneficial effects. Of 30 studies in children living in non-African countries, 10 (n=3105) reported beneficial effects of iron supplementation or fortification on neurobehavioural outcomes, seven (n=786) reported beneficial effects only in children who had iron deficiency, iron deficiency anaemia or anaemia while 13 (n=4803) reported no beneficial effects. 

**Conclusions:** 
There are few studies in African children despite the high burden of iron deficiency and developmental delay in this population. Evidence on the effects of iron supplementation on neurobehavioural outcomes remains unclear and there is need for further well-powered studies evaluating these effects in African populations.
PROSPERO registration: CRD42018091278 (20/03/2018)
AN  - 35106382
AU  - Mutua,
AU  - A.
AU  - M.
AU  - Mwangi,
AU  - K.
AU  - Abubakar,
AU  - A.
AU  - Atkinson,
AU  - S.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.12688/wellcomeopenres.16931.2
L1  - internal-pdf://1214710792/Effects of iron intake on neurobehavioura-2021.pdf
PY  - 2021
SP  - 181
T2  - Wellcome Open Research
TI  - Effects of iron intake on neurobehavioural outcomes in African children: a systematic review and meta-analysis of randomised controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35106382
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8777511/pdf/wellcomeopenres-6-19259.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **Objectives**: Aggression is a substantial behavioral problem in children and adolescents. There has been an increasing amount of research investigating the effectiveness of mindfulness-based intervention (MBI) in reducing levels of aggression. The purpose of this review was to examine how effective mindfulness is in curbing aggressive behaviors in children and adolescents. 

**Methods**: Studies were identified through searching four electronic databases (PsycINFO, CINAHL, MEDLINE, and Web of Science) with combinations of three groups of keywords supplemented with a manual search. Two independent researchers screened the searched papers, extracted data from papers, and assessed the quality of the studies. The extracted data was synthesized narratively and quantitatively. 

**Results**: Eighteen studies (n = 1223) met the inclusion criteria. Three of the studies were controlled trials, seven were quasi-experimental studies, and an additional eight were single-subject design studies. Except for three studies that had unclear methodological quality, the remaining studies showed adequate research quality. Key findings highlighted evidence supporting the effectiveness of the use of MBI in children and adolescents with aggressive behavior problems. The meta-analytical results indicated that the overall effect size of MBI on aggressiveness is moderate (g = 0.48, CI95 [0.33, 0.63], p &lt; 0.001). Furthermore, sub-group analysis estimated different effect sizes for clinical samples (g = 0.59, CI95 [0.23, 0.95], p = 0.001) and non-clinical samples (g = 0.45, CI95 [0.29, 0.62], p &lt; 0.001). 

**Conclusions**: The effectiveness of MBI on child and adolescent aggressive behavior was supported. Compared with non-clinical samples, MBI showed higher effectiveness for clinical samples. Potential mechanisms, methodological strengths and weaknesses, implications, and suggestions for future study are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Zhu, Yuxin: im.usinzu@gmail.comZhu, Yuxin, im.usinzu@gmail.comTao, Sisi: Department of Early Childhood Education, Education University of Hong Kong, Hong Kong, ChinaLi, Jianbin: Department of Early Childhood Education, Education University of Hong Kong, Hong Kong, ChinaZhang, Mengge: Department of Early Childhood Education, Education University of Hong Kong, Hong Kong, ChinaZheng, Pengjuan: Xinlian College of Henan Normal University, Zhengzhou, ChinaLau, Eva Yi Hung: Department of Early Childhood Education, Education University of Hong Kong, Hong Kong, ChinaSun, Jin: Department of Early Childhood Education, Education University of Hong Kong, Hong Kong, ChinaZhu, Yuxin: Department of Health and Physical Education, Education University of Hong Kong, Hong Kong, China
AN  - 2021-06193-001
AU  - Tao,
AU  - S.
AU  - Li,
AU  - J.
AU  - Zhang,
AU  - M.
AU  - Zheng,
AU  - P.
AU  - Lau,
AU  - E.
AU  - Y.
AU  - H.
AU  - Sun,
AU  - J.
AU  - Zhu,
AU  - Y.
DA  - Jun
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12671-020-01570-9
DP  - Ovid Technologies
KW  - Aggression, Mindfulness, Mindfulness-based intervention, Children, Adolescents
KW  - *Aggressive Behavior
KW  - *Behavior Problems
KW  - *Adolescent Health
KW  - *Mindfulness-Based Interventions
KW  - *Child Health
KW  - Databases
KW  - Screening Tests
KW  - Behavior Therapy &amp; Behavior Modification [3312]
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://2936946444/Tao-2021.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2021
SP  - 1301-1315
T2  - Mindfulness
TI  - The effects of mindfulness-based interventions on child and adolescent aggression: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-06193-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs12671-020-01570-9&amp;issn=1868-8527&amp;isbn=&amp;volume=12&amp;issue=6&amp;spage=1301&amp;pages=1301-1315&amp;date=2021&amp;title=Mindfulness&amp;atitle=The+effects+of+mindfulness-based+interventions+on+child+and+adolescent+aggression%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Tao&amp;pid=%3Cauthor%3ETao%2C+Sisi%3C%2Fauthor%3E%3CAN%3E2021-06193-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s12671-020-01570-9.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - Clinical guidelines currently recommend practitioners titrate stimulant medications, i.e., methylphenidate (MPH) and amphetamines (AMP), to the dose that maximizes symptom control without eliciting intolerable adverse events (AEs) when treating attention-deficit/hyperactivity disorder (ADHD) in school-aged children/adolescents. However, robust evidence-base regarding the effects of doses and dosing strategies of stimulants on clinical outcomes in the treatment of children/adolescents with ADHD is currently lacking and stimulants are often underdosed in clinical practice. 

To address this gap and provide rigorous evidence-base in relation to the dose and dosing strategy of stimulants, we conducted the largest systematic review and dose-response meta-analysis examining change in ADHD symptoms (efficacy), and treatment discontinuations due to AEs (tolerability) and any reason (acceptability). 

We conducted one-stage random-effects dose-response meta-analyses examining MPH and AMP separately, stratifying trials based on fixed-dose and flexible-dose design. Daily doses of stimulants were converted to MPH- and AMP-equivalent doses by adjusting for different pharmacokinetics across formulations. We also conducted pairwise meta-analyses to provide indirect comparisons between flexible-dose versus fixed-dose trials. Our study included 65 RCTs involving 7 877 children/adolescents. Meta-analyses of fixed-dose trials for both MPH and AMP demonstrated increased efficacy and increased likelihood of discontinuation due to AEs with increasing doses of stimulants. The incremental benefits of stimulants in terms of efficacy decreased beyond 30 mg of MPH or 20 mg of AMP in fixed-dosed trials. In contrast, meta-analyses of flexible-dose trials for both MPH and AMP demonstrated increased efficacy and reduced likelihood of discontinuations for any reason with increasing stimulant doses. The incremental benefits of stimulants in terms of efficacy remained constant across the FDA-licensed dose range for MPH and AMP in flexible-dose trials. 

Our results suggest that flexible titration as needed, i.e., considering the presence of ADHD symptoms, and tolerated, i.e., considering the presence of dose-limiting AEs, to higher doses of stimulants is associated with both improved efficacy and acceptability because practitioners can increase/reduce doses based on control of ADHD symptoms/dose-limiting AEs. Although fixed-dose trials that are required by the FDA are valuable to characterize dose-dependency, they may underestimate the true potential benefit of trialing dose-increases of stimulants in clinical practice by not allowing dose adjustment based on response and tolerability. Additional research is required to investigate potential long-term effects of using high doses of stimulants in clinical practice.
AN  - WOS:000742278800002
AU  - Farhat,
AU  - L.
AU  - C.
AU  - Flores,
AU  - J.
AU  - M.
AU  - Behling,
AU  - E.
AU  - Avila-Quintero,
AU  - V.
AU  - J.
AU  - Lombroso,
AU  - A.
AU  - Cortese,
AU  - S.
AU  - Polanczyk,
AU  - G.
AU  - V.
AU  - Bloch,
AU  - M.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1038/s41380-021-01391-9
L1  - internal-pdf://0993171148/The effects of stimulant dose and dosing strat.pdf
PY  - 2021
SP  - 11
T2  - Molecular Psychiatry
TI  - The effects of stimulant dose and dosing strategy on treatment outcomes in attention-deficit/hyperactivity disorder in children and adolescents: a meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000742278800002
UR  - https://www.nature.com/articles/s41380-021-01391-9.pdf
ER  -
TY  - JOUR
AB  - Various Cognitive Behavioral Therapy (CBT) programs for externalizing disorders in children and adolescents are supported by a substantial body of empirical evidence. Most of the research evidence comes from efficacy studies conducted in university settings, but there is less knowledge about the effect of these treatments in routine clinical care. The purpose of this meta-analysis was to investigate the effectiveness of CBT in non-university settings for Attention Deficit Hyperactivity Disorder (ADHD), Conduct Disorder (CD) and Oppositional Defiant Disorder (ODD). Embase OVID, Ovid MEDLINE and PsycINFO were systematically searched for eligible studies published up to May 2020. In total, 51 treatment effectiveness studies involving 5295 patients were included. The average within-group effect size at post-treatment was significant (g = 0.91), and there were large effect sizes for both ADHD (g = 0.80) and CD/ODD (g = 0.98). At post treatment, remission rates were 38% for ADHD and 48% for CD/ODD, and the overall attrition rate was 14%. Benchmarking against efficacy studies showed that CBT in routine clinical care yields remission rates, within-group effect sizes and attrition rates that are very similar to those found in university settings. The findings support the transportability of CBT for externalizing disorders from university settings to routine clinical care. PROSPERO registration: CRD42020147524. Copyright &copy; 2020 The Authors
AD  - (Riise) Department of Child and Adolescent Psychiatry, District General Hospital of Forde, Forde, Norway (Wergeland) Department of Child and Adolescent Psychiatry, Division of Psychiatry, Haukeland University Hospital, Bergen, Norway (Wergeland) Department of Clinical Medicine, Faculty of Medicine, University of Bergen, Norway (Njardvik) Department of Psychology, University of Iceland, Reykjavik, Iceland (Ost) Department of Psychology, Stockholm University, Stockholm, Sweden (Ost) Bergen Center for Brain Plasticity, Haukeland University Hospital, Bergen, NorwayE.N. Riise, Department of Child and Adolescent Psychiatry, District General Hospital of Forde, Forde N-6807, Norway. E-mail: eiliriise@gmail.com
AN  - 2010557380
AU  - Riise,
AU  - E.
AU  - N.
AU  - Wergeland,
AU  - G.
AU  - J.
AU  - H.
AU  - Njardvik,
AU  - U.
AU  - Ost,
AU  - L.
AU  - G.
DA  - February
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.cpr.2020.101954
DP  - Ovid Technologies
KW  - Children
KW  - Cognitive behavior therapy
KW  - Externalizing disorders
KW  - Meta-analysis
KW  - Routine care
KW  - adolescent
KW  - attention deficit disorder
KW  - benchmarking
KW  - child
KW  - cognitive behavioral therapy
KW  - conduct disorder
KW  - effect size
KW  - Embase
KW  - female
KW  - human
KW  - male
KW  - Medline
KW  - meta analysis
KW  - oppositional defiant disorder
KW  - PsycINFO
KW  - remission
KW  - review
KW  - systematic review
L1  - internal-pdf://3728125177/Riise-2021.pdf
LA  - English
M3  - Review
PY  - 2021
T2  - Clinical Psychology Review
TI  - Cognitive behavior therapy for externalizing disorders in children and adolescents in routine clinical care: A systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/clinpsychrev
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010557380
VL  - 83 (no pagination)
ER  -
TY  - JOUR
AB  - Eating disorders (EDs) have an estimated prevalence rate of 1%-5% across Europe. Effective adjunct interventions are needed to support the 20%-40% of families whose recovery requires additional support to first line approaches. This systematic review and meta-analysis aimed to establish whether multi-family therapy (MFT) improves the physical and psychological health of patients and family members. 

Searches were conducted in PsycINFO, MEDLINE, PubMed, EMBASE, CINAHL, and the Cochrane Library in March 2021. 15 studies (850 patients) met the inclusion criteria.

Meta-analysis demonstrated MFT resulted in significant benefits in weight gain, ED symptoms, patients&#039; and parents&#039; depression symptoms, and parents&#039; negative experiences of caregiving. However, significant improvements were only evident when comparisons were drawn before and after the intervention; these dissipated when MFT was compared to another intervention. There was no evidence MFT improves family functioning, positive aspects of caregiving, nor patient and parental anxiety. Intervention completion rates ranged from 86% to 100% indicating a high level of acceptability. Studies varied with regard to intervention length and structure, follow-up period, and outcome measures utilised; most were rated as moderate or weak in methodological quality. 

More rigorous and large scale randomised controlled trials are needed to fully assess the effectiveness of MFT.
AN  - WOS:000813986900001
AU  - Zinser,
AU  - J.
AU  - O&#039;Donnell,
AU  - N.
AU  - Hale,
AU  - L.
AU  - Jones,
AU  - C.
AU  - J.
DB  - Alerts 6_2022.enl
DO  - 10.1002/erv.2919
L1  - internal-pdf://3971797642/Euro Eating Disorders Rev - 2022 - Zinser - Mu.pdf
PY  - 2021
SP  - 23
T2  - European Eating Disorders Review
TI  - Multi-family therapy for eating disorders across the lifespan: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000813986900001
ER  -
TY  - JOUR
AB  - BACKGROUND: Pet therapy, or animal-assisted interventions (AAI), have demonstrated positive effects for patients, families and health care providers (HCP) in inpatient settings. However, the evidence supporting AAI in emergency or ambulatory care settings is unclear. We conducted a systematic review to evaluate the effectiveness of AAI on patient, family, and HCP experience in these settings. 

METHODS: We searched (from inception to May 2020) Medline, Embase, Cochrane CENTRAL, PsycINFO, and CINAHL, plus grey literature, for studies assessing AAI in emergency and ambulatory care settings on: 1) patient and family anxiety/distress or pain; and 2) HCP stress. Screening, data extraction and quality assessment were done in duplicate with conflicts adjudicated by a third party. Random-effects meta-analyses are reported as mean differences (MD) or standardized mean differences (SMDs) and 95% confidence intervals (CIs), as appropriate. 

RESULTS: We included 9 randomized controlled trials (RCTs; 341 patients, 146 HCP, 122 child caregivers), 4 before-after (before-after; 83 patients), and 1 mixed-method study (124 patients). There was no effect across three RCTs measuring patient-reported anxiety/distress (n=380; SMD: -0.36, 95% CI: -0.95 to 0.23; I&lt;sup&gt;2&lt;/sup&gt; =81%), while two before-after studies suggested a benefit (n=80; SMD: -1.95, 95% CI: -2.99 to -0.91; I&lt;sup&gt;2&lt;/sup&gt; =72%). Four RCTs found no difference in measures of observed anxiety/distress (n=166; SMD: -0.44; 95% CI: -1.01 to 0.13; I&lt;sup&gt;2&lt;/sup&gt; =73%) while one before-after study reported a significant benefit (n=60; SMD: -1.64, 95% CI: -2.23 to -1.05). Three RCTs found no difference in patient-reported pain (n=202; MD: -0.90; 95% CI: -2.01 to 0.22; I&lt;sup&gt;2&lt;/sup&gt; =68%). Two RCTs reported positive but non-significant effects on HCP stress. 

CONCLUSIONS: Limited evidence is available on the effectiveness of AAI in emergency and ambulatory care settings. Rigorous studies using global experience-oriented (or patient-identified) outcome measures are required.
AN  - 34817908
AU  - Gaudet,
AU  - L.
AU  - A.
AU  - Elliott,
AU  - S.
AU  - A.
AU  - Ali,
AU  - S.
AU  - Kammerer,
AU  - E.
AU  - Stauffer,
AU  - B.
AU  - Felkar,
AU  - B.
AU  - Scott,
AU  - S.
AU  - D.
AU  - Dennett,
AU  - L.
AU  - Hartling,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/acem.14421
L1  - internal-pdf://2687020541/Gaudet-2021.pdf
PY  - 2021
SP  - 24
T2  - Academic Emergency Medicine
TI  - Pet Therapy in the Emergency Department and Ambulatory Care: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34817908
UR  - https://onlinelibrary.wiley.com/doi/10.1111/acem.14421
VL  - 24
ER  -
TY  - JOUR
AB  - **Background** Self‐harm (SH; intentional self‐poisoning or self‐injury regardless of degree of suicidal intent or other types of motivation) is a growing problem in most countries, often repeated, and associated with suicide. Evidence assessing the effectiveness of interventions in the treatment of SH in children and adolescents is lacking, especially when compared with the evidence for psychosocial interventions in adults. This review therefore updates a previous Cochrane Review (last published in 2015) on the role of interventions for SH in children and adolescents.

**Objectives** To assess the effects of psychosocial interventions or pharmacological agents or natural products for SH compared to comparison types of care (e.g. treatment‐as‐usual, routine psychiatric care, enhanced usual care, active comparator, placebo, alternative pharmacological treatment, or a combination of these) for children and adolescents (up to 18 years of age) who engage in SH.Search methodsWe searched the Cochrane Common Mental Disorders Specialized Register, the Cochrane Library (Central Register of Controlled Trials [CENTRAL] and Cochrane Database of Systematic Reviews [CDSR]), together with MEDLINE, Ovid Embase, and PsycINFO (to 4 July 2020).Selection criteriaWe included all randomised controlled trials (RCTs) comparing specific psychosocial interventions or pharmacological agents or natural products with treatment‐as‐usual (TAU), routine psychiatric care, enhanced usual care (EUC), active comparator, placebo, alternative pharmacological treatment, or a combination of these, in children and adolescents with a recent (within six months of trial entry) episode of SH resulting in presentation to hospital or clinical services. The primary outcome was the occurrence of a repeated episode of SH over a maximum follow‐up period of two years. Secondary outcomes included treatment adherence, depression, hopelessness, general functioning, social functioning, suicidal ideation, and suicide.Data collection and analysisWe independently selected trials, extracted data, and appraised trial quality. For binary outcomes, we calculated odds ratios (ORs) and their 95% confidence internals (CIs). For continuous outcomes, we calculated the mean difference (MD) or standardised mean difference (SMD) and 95% CIs. The overall quality of evidence for the primary outcome (i.e. repetition of SH at post‐intervention) was appraised for each intervention using the GRADE approach.

**Main results** We included data from 17 trials with a total of 2280 participants. Participants in these trials were predominately female (87.6%) with a mean age of 14.7 years (standard deviation (SD) 1.5 years). The trials included in this review investigated the effectiveness of various forms of psychosocial interventions. None of the included trials evaluated the effectiveness of pharmacological agents in this clinical population. There was a lower rate of SH repetition for DBT‐A (30%) as compared to TAU, EUC, or alternative psychotherapy (43%) on repetition of SH at post‐intervention in four trials (OR 0.46, 95% CI 0.26 to 0.82; N = 270; k = 4; high‐certainty evidence). There may be no evidence of a difference for individual cognitive behavioural therapy (CBT)‐based psychotherapy and TAU for repetition of SH at post‐intervention (OR 0.93, 95% CI 0.12 to 7.24; N = 51; k = 2; low‐certainty evidence). We are uncertain whether mentalisation based therapy for adolescents (MBT‐A) reduces repetition of SH at post‐intervention as compared to TAU (OR 0.70, 95% CI 0.06 to 8.46; N = 85; k = 2; very low‐certainty evidence). Heterogeneity for this outcome was substantial ( I&sup2; = 68%). There is probably no evidence of a difference between family therapy and either TAU or EUC on repetition of SH at post‐intervention (OR 1.00, 95% CI 0.49 to 2.07; N = 191; k = 2; moderate‐certainty evidence). However, there was no evidence of a difference for compliance enhancement approaches on repetition of SH by the six‐month follow‐up assessment, for group‐based psychotherapy at the six‐ or 12‐month follow‐up assessments, for a remote contact intervention (emergency cards) at the 12‐month assessment, or for therapeutic assessment at the 12‐ or 24‐month follow‐up assessments.

**Authors&#039; conclusions** Given the moderate or very low quality of the available evidence, and the small number of trials identified, there is only uncertain evidence regarding a number of psychosocial interventions in children and adolescents who engage in SH. Further evaluation of DBT‐A is warranted. Given the evidence for its benefit in adults who engage in SH, individual CBT‐based psychotherapy should also be further developed and evaluated in children and adolescents.
AU  - Witt,
AU  - K.
AU  - G.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Rajaram,
AU  - G.
AU  - Hazell,
AU  - P.
AU  - Taylor
AU  - Salisbury
AU  - T.
AU  - L.
AU  - Townsend,
AU  - E.
AU  - Hawton,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013667.pub2
L1  - internal-pdf://3575854995/Witt_et_al-2021-Cochrane_Database_of_Systemati.pdf
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for self‐harm in children and adolescents
ER  -
TY  - JOUR
AB  - This review aims to evaluate the effectiveness of virtual reality-based interventions (VR-based interventions) on cognitive deficits in children with attention deficit hyperactivity disorder (ADHD). A systematic review and meta-analysis were performed according to the PRISMA statement and the Cochrane Handbook guidelines for conducting meta-analyses. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) was used to assess the quality of the evidence. Clinical trials published up to 29 October 2020, were included. The meta-analysis included four studies, with a population of 125 participants with ADHD. The magnitude of the effect was large for omissions (SMD = -1.38; p = 0.009), correct hits (SMD = -1.50; p = 0.004), and perceptual sensitivity (SMD = -1.07; p = 0.01); and moderate for commissions (SMD = -0.62; p = 0.002) and reaction time (SMD = -0.67; p = 0.03). The use of VR-based interventions for cognitive rehabilitation in children with ADHD is limited. The results showed that VR-based interventions are more effective in improving sustained attention. Improvements were observed in attentional vigilance measures, increasing the number of correct responses and decreasing the number of errors of omission. No improvements were observed in impulsivity responses.
AD  - Romero-Ayuso, Dulce. Department of Physical Therapy, Occupational Therapy Division, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.Toledano-Gonzalez, Abel. Faculty of Health Sciences, University of Castilla-La Mancha, Talavera la de Reina, 45600 Toledo, Spain.Rodriguez-Martinez, Maria Del Carmen. Faculty of Health Sciences, Universidad de Malaga, 29016 Malaga, Spain.Arroyo-Castillo, Palma. Department of Physical Therapy, Occupational Therapy Division, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.Trivino-Juarez, Jose Matias. Primary Care Center Zaidin Sur, Granada Metropolitan Sanitary District, 18007 Granada, Spain.Gonzalez, Pascual. LoUISE Research Group, Computing Systems Department, University of Castilla-La Mancha, 02071 Albacete, Spain.Ariza-Vega, Patrocinio. Department of Physical Therapy, Occupational Therapy Division, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.Gonzalez, Antonio Del Pino. Department of Educational Orientation, IES Maximo Laguna, Consejeria de Educacion, Junta de Castilla-La Mancha, Santa Cruz de Mudela, 13730 Ciudad Real, Spain.Segura-Fragoso, Antonio. Faculty of Health Sciences, University of Castilla-La Mancha, Talavera la de Reina, 45600 Toledo, Spain.
AN  - 33494272
AU  - Romero-Ayuso,
AU  - D.
AU  - Toledano-Gonzalez,
AU  - A.
AU  - Rodriguez-Martinez,
AU  - M.
AU  - D.
AU  - C.
AU  - Arroyo-Castillo,
AU  - P.
AU  - Trivino-Juarez,
AU  - J.
AU  - M.
AU  - Gonzalez,
AU  - P.
AU  - Ariza-Vega,
AU  - P.
AU  - Gonzalez,
AU  - A.
AU  - D.
AU  - P.
AU  - Segura-Fragoso,
AU  - A.
DA  - Jan 21
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/children8020070
DP  - Ovid Technologies
J2  - Children (Basel)
L1  - internal-pdf://1948694928/Romero-Ayuso-2021-Effectiveness of Virtual Rea.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingJanRomero-Ayuso, DulceToledano-Gonzalez, AbelRodriguez-Martinez, Maria Del CarmenArroyo-Castillo, PalmaTrivino-Juarez, Jose MatiasGonzalez, PascualAriza-Vega, PatrocinioGonzalez, Antonio Del PinoSegura-Fragoso, Antonio70
PY  - 2021
SP  - 21
T2  - Children
TI  - Effectiveness of Virtual Reality-Based Interventions for Children and Adolescents with ADHD: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33494272
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33494272&amp;id=doi:10.3390%2Fchildren8020070&amp;issn=2227-9067&amp;isbn=&amp;volume=8&amp;issue=2&amp;spage=&amp;pages=&amp;date=2021&amp;title=Children&amp;atitle=Effectiveness+of+Virtual+Reality-Based+Interventions+for+Children+and+Adolescents+with+ADHD%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Romero-Ayuso&amp;pid=%3Cauthor%3ERomero-Ayuso+D%3C%2Fauthor%3E%3CAN%3E33494272%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://res.mdpi.com/d_attachment/children/children-08-00070/article_deploy/children-08-00070-v2.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **Background**: There is emerging evidence to show that psychological interventions such as cognitive remediation therapy (CRT), psychoeducation, family therapy, and group psychotherapies may be useful for adolescents with psychosis. The current review is on the effects of various psychological interventions for adolescents with psychosis compared with treatment as usual (TAU) or other psychological interventions. 

**Method(s)**: We undertook a comprehensive search for all randomized controlled trials on the topic as per predefined criteria. For binary data, a standard estimation of risk ratio, and, for continuous data, the mean difference between groups were estimated. GRADE approach was used to assess studies. &quot;Risk of Bias&quot;was calculated, and finally random-effects model was used for analyses. 

**Result(s)**: The review included 7 studies (n = 317). Two studies compared CRT and TAU with TAU alone. CRT showed improvement in short-term memory compared with those in the TAU group (relative risk 0.58, 95% CI 0.37 to 0.89, participants = 31, very low-certainty evidence). When comparing group psychosocial therapy with TAU, global state scores measured using Children&#039;s Global Assessment Scale (CGAS) were clearly higher in the intervention arm (mean difference 5.10, 95% CI 1.35 to 8.85, participants = 56, very low-certainty evidence) as compared with the TAU group. None of the other interventions were found to be significantly effective for the treatment of psychosis in adolescents. 

**Conclusion(s)**: Evidence suggests that psychological interventions may have beneficial effects in the treatment of adolescents with psychosis, but the evidence is of low or very low certainty. Copyright &copy; 2020 The Author(s). Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved.
AN  - 2012223275
AU  - Daruvala,
AU  - R.
AU  - Kumar,
AU  - A.
AU  - Datta,
AU  - S.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/schbul/sbaa132
L1  - internal-pdf://1320581908/Daruvala-2021-Do Psychological Interventions W.pdf
PY  - 2021
SP  - 692-694
T2  - Schizophrenia Bulletin
TI  - Do Psychological Interventions Work for Psychosis in Adolescents?
UR  - http://schizophreniabulletin.oxfordjournals.org/
UR  - https://academic.oup.com/schizophreniabulletin/article-abstract/47/3/692/5911651?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/sbaa132.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAwAwggL8BgkqhkiG9w0BBwagggLtMIIC6QIBADCCAuIGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMpAu74JocD2lSdoqLAgEQgIICsy2dMe0D_E6RP09j5OSk8vrzwkxKGhjDgoH30Zgyx3cVtV9S_ZCFHiWez-fCUYzDRjgJ3YohYmH3ncwy_sQI26HT0DQZtKgdAhmeC6E7cPD27qhs9SmOXU8vgzC_o-TkqhOGww1qtnKpZFMeunZDg5hMHHMS70h4GeGbNnlWPCzqkAX1G1SdZUtFPkuMNQ_9JvO2J7VCVQE4QPfpjqLJuBhcMreEko0l2Kh6FZf2Etzw3tpYJmeGA5EO3OPgLjxAEn4zr7ft-vpd06xute2-bXPhKOtxiIZln7NMf4fn-s1C4g1hHdxKLACzLkwMIjmEaSNUE3AnU2f9ZEeF0feAkpm5B9DOTiiArY6V99Flfp0Vk6UFGYGQbtQtR8mN-p8KuKYZKOOmabLDncdh98zWxBfUXoGt-fetR6Hxte-n0B4-RKboLGFRP8YZFY5YFqisPwt1k5yWtC-ySA5OQsOKc9Ssue9CjgCA74jf36oHMZQEIzqhoh_Aolw6xvv-4iiU6EootZOi7wCykg-e_M7xomqgtfDRwsb7KsPPN9cOHmjH8CUwtSQFXy9pN1--4w_Fu3giYuwwNtp49ffFoW8xvB-58yK73YRKJO9MYPmp5cV5S-n7hlYt2x1BawNewVT0syG5zRM8OkqG6E9C1CbJxhYjYnn6iyLvvdl3oJxpY6NBl6LQOb9lzs-fwnAb68y9u4U3qA4iqIhSO0U_UJiuq8C806PaxliMiG42wVCYKvStM_21iYsiTkAmn1O_riPx6J1WUxouAaA6-qGzn7wpKJGzPkv6U1HZzCnToRqvzQCb93qkfQaMrYUqiMUQfGYsbPIbJP79aUf-WxfZ1Nn7fO2WRMj1G1aWh9_WPzqr2aUwBpcIXzw8yuhDizNyWOuiCBcfHRBIYfed_0ivE3NLmNdNzro
VL  - 47
ER  -
TY  - JOUR
AB  - The nature and magnitude of placebo and nocebo responses to ADHD medications and the extent to which response to active medications and placebo are inter-correlated is unclear. To assess the magnitude of placebo and nocebo responses to ADHD and their association with active treatment response. We searched literature until June 26, 2019, for published/unpublished double-blind, randomised placebo-controlled trials (RCTs) of ADHD medication. Authors were contacted for additional data. We assessed placebo effects on efficacy and nocebo effects on tolerability using random effects meta-analysis. We assessed the association of study design and patient features with placebo/nocebo response. We analysed 128 RCTs (10,578 children/adolescents and 9175 adults) and found significant and heterogenous placebo effects for all efficacy outcomes, with no publication bias. The placebo effect was greatest for clinician compared with other raters. We found nocebo effects on tolerability outcomes. Efficacy outcomes from most raters showed significant positive correlations between the baseline to endpoint placebo effects and the baseline to endpoint drug effects. Placebo and nocebo effects did not differ among drugs. Baseline severity and type of rating scale influenced the findings. Shared non-specific factors influence response to both placebo and active medication. Although ADHD medications are superior to placebo, and placebo treatment in clinical practice is not feasible, clinicians should attempt to incorporate factors associated with placebo effects into clinical care. Future studies should explore how such effects influence response to medication treatment. Upon publication, data will be available in Mendeley Data: PROSPERO (CRD42019130292).
AN  - WOS:000648813500003
AU  - Faraone,
AU  - S.
AU  - V.
AU  - Newcorn,
AU  - J.
AU  - H.
AU  - Cipriani,
AU  - A.
AU  - Brandeis,
AU  - D.
AU  - Kaiser,
AU  - A.
AU  - Hohmann,
AU  - S.
AU  - Haege,
AU  - A.
AU  - Cortese,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1038/s41380-021-01134-w
L1  - internal-pdf://2885827677/Faraone.pdf
PY  - 2021
T2  - MOLECULAR PSYCHIATRY
TI  - Placebo and nocebo responses in randomised, controlled trials of medications for ADHD: a systematic review and meta-analysis
UR  - https://www.nature.com/articles/s41380-021-01134-w
UR  - https://www.nature.com/articles/s41380-021-01134-w.pdf
ER  -
TY  - JOUR
AB  - Global estimates suggest that 25% and 20% of youth have reported elevated symptoms of depression and anxiety, respectively, since the beginning of the COVID-19 pandemic compared to baseline functioning (Racine et al., 2021). Cognitive behavioural therapy (CBT) has been found to significantly benefit young people experiencing anxiety and depression (Christ et al., 2020). Pandemic-related protocols have led many mental health services to shift to online platforms.

 We wondered about the comparative efficacy of online versus offline CBT for young people between the ages of 10-25. We responded with a rapid review and meta-analysis of eight randomised controlled trial (RCT) outcomes. 

The sample-weighted, between-group effect size, the standardised mean difference (d), was essentially zero at longest follow-up (nine months), indicating that online and offline CBT were equally effective for youth with depression and anxiety; both online and offline groups&#039; symptom alleviation rates were approximately 90%. Recognising a lack of diversity in the samples has led us to argue that comparative meta-analyses across the most potentially vulnerable minoritised groups should be a focus in future research. This would help social workers and allied mental health providers support diverse clients and decision makers navigate the troubled clinical and social policy waters of the pandemic and its aftermath. 

**IMPLICATIONS** Online CBT seems as effective as offline CBT in alleviating anxiety and depressive symptoms among young people, including young adults beginning to develop symptoms. A more socially, racially, and gender-inclusive RCT-based synthetic research agenda is needed to steer online versus offline decisions in social work and allied mental health. Social work&#039;s emphasis on diversity, equity, and inclusion has, with the focus of rigorous research, the potential to play an important role in addressing gendered, cultural, and socioeconomic knowledge gaps.
AN  - WOS:000724027400001
AU  - Howes,
AU  - S.
AU  - T.
AU  - Gorey,
AU  - K.
AU  - M.
AU  - Charron,
AU  - C.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/0312407x.2021.2001832
L1  - internal-pdf://3696434983/Relative Effectiveness of Online Cognitive Beh.pdf
PY  - 2021
SP  - 15
T2  - Australian Social Work
TI  - Relative Effectiveness of Online Cognitive Behavioural Therapy with Anxious or Depressed Young People: Rapid Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000724027400001
UR  - https://www.tandfonline.com/doi/full/10.1080/0312407X.2021.2001832
ER  -
TY  - JOUR
AB  - **Background**: Educational interventions engage youth using visual, literary and performing arts to combat stigma associated with mental health problems. However, it remains unknown whether arts interventions are effective in reducing mental-health-related stigma among youth and if so, then which specific art forms, duration and stigma-related components in content are successful. 

**Method(s)**: We searched 13 databases, including PubMed, Medline, Global Health, EMBASE, ADOLEC, Social Policy and Practice, Database of Promoting Health Effectiveness Reviews (DoPHER), Trials Register of Promoting Health Interventions (TRoPHI), EPPI-Centre database of health promotion research (Bibliomap), Web of Science, PsycINFO, Cochrane and Scopus for studies involving arts interventions aimed at reducing any or all components of mental-health-related stigma among youth (10-24-year-olds). Risk of bias was assessed using the Effective Public Health Practice Project (EPHPP) Quality Assessment Tool for Quantitative Studies. Data were extracted into tables and analysed using RevMan 5.3.5. 

**Result(s)**: Fifty-seven studies met our inclusion criteria (n = 41,621). Interventions using multiple art forms are effective in improving behaviour towards people with mental health problems to a small effect (effect size = 0.28, 95%CI 0.08-0.48; p = 0.007) No studies reported negative outcomes or unintended harms. Among studies using specific art forms, we observed high heterogeneity among intervention studies using theatre, multiple art forms, film and role play. Data in this review are inconclusive about the use of single versus multiple sessions and whether including all stigma components of knowledge, attitude and behaviour as intervention content are more effective relative to studies focused on these stigma components, individually. Common challenges faced by school-based arts interventions included lack of buy-in from school administrators and low engagement. No studies were reported from low- and middle-income countries. 

**Conclusion(s)**: Arts interventions are effective in reducing mental-health-related stigma to a small effect. Interventions that employ multiple art forms together compared to studies employing film, theatre or role play are likely more effective in reducing mental-health-related stigma. Copyright &copy; 2021, The Author(s).
AN  - 2013241946
AU  - Gaiha,
AU  - S.
AU  - M.
AU  - Salisbury,
AU  - T.
AU  - T.
AU  - Usmani,
AU  - S.
AU  - Koschorke,
AU  - M.
AU  - Raman,
AU  - U.
AU  - Petticrew,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12888-021-03350-8
L1  - internal-pdf://2496699073/Gaiha-2021-Effectiveness of arts interventions.pdf
PY  - 2021
T2  - BMC Psychiatry
TI  - Effectiveness of arts interventions to reduce mental-health-related stigma among youth: a systematic review and meta-analysis
UR  - https://bmcpsychiatry.biomedcentral.com/
UR  - https://bmcpsychiatry.biomedcentral.com/track/pdf/10.1186/s12888-021-03350-8.pdf
VL  - 21 (1) (no pagination)
ER  -
TY  - JOUR
AB  - **Objectives** 
Mindfulness-based interventions (MBIs) are being increasingly used toward improving mental health. Previous studies reached inconsistent conclusions regarding the effects of MBIs on the well-being and psychological distress of children and adolescents. Therefore, we conducted a meta-analysis summarizing the effects of MBIs on the well-being and psychological distress (i.e., anxiety, depression, and stress) of children and adolescents.

**Methods**
We searched electronic databases for reports on randomized controlled trials (RCTs) published until November 2020. Random effects models were used to calculate the overall effect size of each outcome variable for all participants. Subgroup and meta-regression analyses were conducted for categorical and continuous variables, respectively.

**Results**
A total of 28 RCT studies (48 independent samples), comprising 7943 participants, were included in the final synthesis. The MBIs had a small effect on anxiety (g = 0.39), depression (g = 0.28), and stress (g = 0.30), and no significant effect on well-being. Subgroup analyses showed intervention time, mindfulness type, control type, and intervention population to be significant moderators. However, meta-regression analyses indicated that effect sizes were not moderated by intervention duration or study quality.

**Conclusions**
Our results confirmed MBI to be an alternative intervention for reducing psychological distress among both children and adolescents. The development and application of a shorter MBI, adapted for adolescents, could be addressed in future studies. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2022-10018-001
AU  - Zhang,
AU  - Y.
AU  - Chen,
AU  - S.
AU  - Wu,
AU  - H.
AU  - Guo,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12671-021-01775-6
L1  - internal-pdf://2430153735/Zhang-2021-Effect of mindfulness on psychologi.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Mindfulness
TI  - Effect of mindfulness on psychological distress and well-being of children and adolescents: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2022-10018-001
UR  - https://link.springer.com/content/pdf/10.1007/s12671-021-01775-6.pdf
ER  -
TY  - JOUR
AB  - **Objectives**
To evaluate the efficacy in reduction of depressive symptoms, and safety and tolerability of second-generation antipsychotics (SGAs) to manage pediatric bipolar depression (PBD). 

**Methods**
We conducted a systematic review for randomized clinical trials (RCTs) for PBD in MEDLINE, Scopus, and EMBASE. Four (quetiapine: 2, lurasidone: 1, olanzapine-fluoxetine combination [OFC]: 1) out of 569 studies met the criteria for inclusion in meta-analysis. RevMan was used for statistical analysis, and the mean difference (MD) between mean children&#039;s depression rating scale-revised (CDRS-R) score was used to measure treatment difference between SGA and placebo. 

**Results**
Lurasidone displayed a significant reduction in depressive symptoms (MD -5.70, 95% confidence interval [CI] -8.67 to -2.73) in PBD, followed by OFC (MD -5.00, 95% CI -8.64 to -1.36) and quetiapine (MD -2.30, 95% CI -6.80 to 2.20; MD 1.00, 95% CI -9.88 to 11.88). The response was significantly higher for lurasidone (59.5% vs. 36.5%; p &lt; 0.001) and OFC (78.2% vs. 59.2%, p = 0.003) compared with placebo. There was no statistically significant MD in treatment and response rates between quetiapine and placebo in all RCTs. The weighted mean CDRS-R total score difference was -4.58 (95% CI -6.59 to -2.56) and overall effect was significant (p &lt; 0.00001). Importantly, the p value for heterogeneity was 0.46, which indicated that there was no heterogeneity between outcomes of the studies. The number needed to treat (NNT) for lurasidone was 4.3, followed by OFC (NNT = 5.3) and quetiapine (NNT = 12.5; NNT = 25). 

**Conclusion**
Our findings showed lurasidone and OFC were more efficacious than placebo for acute depressive episodes in PBD. RCTs of treatments for PBD remain scarce pressing the need for more research.
AN  - 34665020
AU  - Patel,
AU  - R.
AU  - S.
AU  - Veluri,
AU  - N.
AU  - Patel,
AU  - J.
AU  - Patel,
AU  - R.
AU  - Machado,
AU  - T.
AU  - Diler,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1089/cap.2021.0031
L1  - internal-pdf://3517110647/Patel-2021-Second-Generation Antipsychotics in.pdf
PY  - 2021
SP  - 521-530
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Second-Generation Antipsychotics in Management of Acute Pediatric Bipolar Depression: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34665020
UR  - https://www.liebertpub.com/doi/pdf/10.1089/cap.2021.0031?download=true
VL  - 31
ER  -
TY  - JOUR
AB  - Communicating with peers often poses challenges for individuals with autism spectrum disorder (ASD); these social interactions, however, can be especially difficult during the teenage years. For many adolescents with ASD, peer interaction is often limited or nonexistent, even for those taught in general education settings. 

The purpose of this meta-analysis was to investigate social interaction interventions for adolescents with ASD within public school settings, with a focus on studies that utilized single-case design. Studies were evaluated per the What Works Clearinghouse guidelines. 

This meta-analysis includes 24 studies with participants with ASD ranging in ages from 13 to 21 years. The effects of social skill interventions were evaluated using visual analysis, Tau-U, and a parametric effect size (d-Hedges-Pustejovsky-Shadish [DHPS]). Combined effect sizes were calculated and compared. 

Results provide evidence that interventions can produce positive change in social behavior of adolescents with ASD. Effect sizes were generally large. Interpretations and implications are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-86485-006
AU  - Babb,
AU  - S.
AU  - Raulston,
AU  - T.
AU  - J.
AU  - McNaughton,
AU  - D.
AU  - Lee,
AU  - J.-Y.
AU  - Weintraub,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/0741932520956362
L1  - internal-pdf://1751649058/Babb-2021-The effects of social skill interven.pdf
PY  - 2021
SP  - 343-357
T2  - Remedial and Special Education
TI  - The effects of social skill interventions for adolescents with autism: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2021-86485-006
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0741932520956362
VL  - 42
ER  -
TY  - JOUR
AB  - This review synthesized the results of 15 studies (with 12 studies having strong or adequate methodological rigor) that examined the social outcomes of shared social activity-based interventions, like interest-based games, music, and theatre, involving children on the autism spectrum and typical development together. 

Thirteen studies yielded significant improvements in social cognition, social communication, and/or social functioning with two studies also reporting an increase in positive affect between autistic children and their peers. 

Overall, shared social activities that promote a sense of equality, are enjoyable, and build on the natural talents of children on the autism spectrum appear promising for increasing social learning within inclusive environments.
AN  - WOS:000801119700001
AU  - Dahary,
AU  - H.
AU  - Rimmer,
AU  - C.
AU  - Kaedbey,
AU  - M.
AU  - Quintin,
AU  - E.
AU  - M.
DB  - Alerts 6_2022.enl
DO  - 10.1007/s40489-022-00322-w
L1  - internal-pdf://1940045429/Dahary-A Systematic Review of Shared Social Ac.pdf
PY  - 2021
SP  - 22
T2  - Review Journal of Autism and Developmental Disorders
TI  - A Systematic Review of Shared Social Activities for Children on the Autism Spectrum and Their Peers
UR  - &lt;Go to ISI&gt;://WOS:000801119700001
UR  - https://link.springer.com/article/10.1007/s40489-022-00322-w
UR  - https://link.springer.com/content/pdf/10.1007/s40489-022-00322-w.pdf
ER  -
TY  - JOUR
AB  - The purpose of this study was to determine whether the augmented reality in children with autism spectrum disorder is an evidence-based practice. 

For this purpose, a systematic literature review was conducted for determining research that implemented the augmented reality. The review followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. 

As a result of the review, nine single-case experimental design (SCED) research that met the inclusion criteria were analyzed using the quality indicators. At the end of the quality evaluation, the effect size of eight SCED research that were determined to have evidence of a strong or adequate quality was calculated by using Tau-U. 

The results of the study revealed that the augmented reality was a promising and highly effective intervention (Tau U = 0.98) in teaching new skills for children with autism spectrum disorder. 

(PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-85015-001
AU  - Denizli-Gulboy,
AU  - H.
AU  - Genc-Tosun,
AU  - D.
AU  - Gulboy,
AU  - E.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/20473869.2021.1972741
L1  - internal-pdf://0612573389/Denizli-Gulboy-2021-Evaluating augmented reali.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - International Journal of Developmental Disabilities
TI  - Evaluating augmented reality as evidence-based practice for individuals with autism spectrum disorder: A meta-analysis of single-case design studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-85015-001
UR  - https://www.tandfonline.com/doi/full/10.1080/20473869.2021.1972741
UR  - https://www.tandfonline.com/doi/pdf/10.1080/20473869.2021.1972741?needAccess=true
ER  -
TY  - JOUR
AB  - **Importance**
Social deficits are a common and disabling feature of many pediatric disorders; however, whether behavioral interventions are associated with benefits for children and adolescents with social deficits is poorly understood. 

**Objective**
To assess whether behavioral interventions in children and adolescents with neurodevelopmental or mental health disorders are associated with improvements in social function and social cognition, and whether patient, intervention, and methodological characteristics moderate the association. 

**Data Sources**
For this systematic review and meta-analysis, the PsycINFO, MEDLINE, and PubMed electronic databases were searched in December 2020 for randomized clinical trials published from database inception to December 1, 2020, including terms related to neurodevelopmental or mental health disorders, social behavior, randomized clinical trials, and children and adolescents. Data were analyzed in January 2021. 

**Study Selection**
Randomized clinical trials that enrolled participants aged 4 to 17 years with social deficits and examined the efficacy of a clinician-administered behavioral intervention targeting social functioning or social cognition were included. A total of 9314 records were identified, 78 full texts were assessed for eligibility, and 33 articles were included in the study; 31 of these reported social function outcomes and 12 reported social cognition outcomes. Data Extraction and Synthesis: Articles were reviewed using the Cochrane Risk of Bias Assessment for randomized clinical trials. Data were independently extracted and pooled using a weighted random-effects model. 

**Main Outcomes and Measures**
The main outcome was the association of behavioral intervention with social function and social cognition. Hedges g was used to measure the standardized mean difference between intervention and control groups. Standardized effect sizes were calculated for the intervention group vs the comparison group for each trial. Results: A total of 31 trials including 2131 participants (1711 [80%] male; 420 [20%] female; mean [SD] age, 10.8 [2.2] years) with neurodevelopmental or mental health disorders (autism spectrum disorder [ASD] [n = 23], attention-deficit/hyperactivity disorder [n = 4], other conditions associated with social deficits [n = 4]) were analyzed to examine differences in social function between the intervention and control groups. Significantly greater gains in social function were found among participants who received an intervention than among the control groups (Hedges g, 0.61; 95% CI, 0.40-0.83; P &lt; .001). The type of control condition (wait list vs active control vs treatment as usual) was a significant moderator of effect size (Q2, 7.11; P = .03). Twelve studies including 487 individuals with ASD (48 [10%] female; 439 [90%] male; mean [SD] age, 10.4 [1.7] years) were analyzed to examine differences in social cognition between intervention and control groups. The overall mean weighted effect was significant (Hedges g, 0.67; 95% CI, 0.39-0.96; P &lt; .001), indicating the treatment groups had better performance on social cognitive tasks. 

**Conclusions and Relevance**
In this systematic review and meta-analysis, significantly greater gains in social function and social cognition were reported among children and adolescents who received behavioral interventions for social deficits compared with participants receiving the control conditions. These findings suggest that children and adolescents with social deficits might benefit from social skills training regardless of their specific neurodevelopmental or mental health diagnosis.
AN  - 34661613
AU  - Darling,
AU  - S.
AU  - J.
AU  - Goods,
AU  - M.
AU  - Ryan,
AU  - N.
AU  - P.
AU  - Chisholm,
AU  - A.
AU  - K.
AU  - Haebich,
AU  - K.
AU  - Payne,
AU  - J.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1001/jamapediatrics.2021.3982
L1  - internal-pdf://3695954907/Darling-2021-Behavioral Intervention for Socia.pdf
PY  - 2021
SP  - e213982
T2  - JAMA Pediatrics
TI  - Behavioral Intervention for Social Challenges in Children and Adolescents: A Systematic Review and Meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34661613
UR  - https://jamanetwork.com/journals/jamapediatrics/article-abstract/2785246
UR  - https://jamanetwork.com/journals/jamapediatrics/articlepdf/2785246/jamapediatrics_darling_2021_oi_210058_1633967681.21153.pdf
ER  -
TY  - JOUR
AB  - **Background**
The purpose of this study was to systematically review the effectiveness of Tai Chi and Qigong exercise on adolescents&#039; symptoms of depression and anxiety, and psychological status based on clinical evidences, and to calculate the pooled results using meta-analysis.
AN  - 34899487
AU  - Liu,
AU  - X.
AU  - Li,
AU  - R.
AU  - Cui,
AU  - J.
AU  - Liu,
AU  - F.
AU  - Smith,
AU  - L.
AU  - Chen,
AU  - X.
AU  - Zhang,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyg.2021.746975
L1  - internal-pdf://3869714745/Liu-2021-The Effects of Tai Chi and Qigong Exe.pdf
PY  - 2021
SP  - 746975
T2  - Frontiers in Psychology
TI  - The Effects of Tai Chi and Qigong Exercise on Psychological Status in Adolescents: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34899487
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652254/pdf/fpsyg-12-746975.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **Objectives**: This meta-analysis summarizes recent experimental evidence on school-based interventions designed to reduce student suspensions and arrests. 

**Methods**: Eligible studies included randomized controlled trials from 2008 to 2019 with at least 100 students and an official measure of either suspension or arrest. Fourteen studies were found, resulting in 12 suspension effects and 6 arrest effects. 

**Results**: Overall, interventions showed small but not statistically significant reductions in arrests and suspensions. The weighted mean of the arrest effects was Cohen&#039;s d = -0.013 (p = .093) and the weighted mean of the suspension effects was d = -0.033 (p = .215). Suspension effects differed by intervention characteristics: well-implemented interventions demonstrated significant reductions in student suspensions (d = -0.11, p &lt; .001) but interventions with explicit implementation problems did not (d = 0.047, p = .084). Interventions in high schools reduced suspensions significantly (d = -0.137, p = .003) whereas elementary school interventions did not (d = -0.021, p = .251). 

**Conclusions**: Well-implemented school-based interventions may reduce suspensions by building positive environments and providing supports for students. More research should be done to identify ways in which these and other programs can best be implemented to reduce suspensions and arrests. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Mielke, Monica: mielke@sas.upenn.edu; Farrington, David P.: dpf1@cam.ac.ukMielke, Monica: Department of Criminology, 3718 Locust Walk, 558 McNeil Building, Philadelphia, PA, US, 19104, mielke@sas.upenn.eduMielke, Monica: Department of Criminology, University of Pennsylvania, Philadelphia, PA, USFarrington, David P.: Institute of Criminology, University of Cambridge, Cambridge, United Kingdom
AN  - 2021-10357-001
AU  - Mielke,
AU  - M.
AU  - Farrington,
AU  - D.
AU  - P.
DA  - Jan-Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.avb.2020.101518
DP  - Ovid Technologies
KW  - School suspension, School discipline, Juvenile arrest, Meta-analysis
KW  - *Classroom Discipline
KW  - *School Based Intervention
KW  - *School Suspension
KW  - Juvenile Delinquency
KW  - Curriculum &amp; Programs &amp; Teaching Methods [3530]
KW  - Criminal Behavior &amp; Juvenile Delinquency [3236]
KW  - Human
L1  - internal-pdf://4035911292/Mielke-2021.pdf
LA  - English
M3  - Meta Analysis
PY  - 2021
T2  - Aggression and Violent Behavior Vol 56 2021, ArtID 101518
TI  - School-based interventions to reduce suspension and arrest: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-10357-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.avb.2020.101518&amp;issn=1359-1789&amp;isbn=&amp;volume=56&amp;issue=&amp;spage=101518&amp;pages=&amp;date=2021&amp;title=Aggression+and+Violent+Behavior&amp;atitle=School-based+interventions+to+reduce+suspension+and+arrest%3A+A+meta-analysis.&amp;aulast=Mielke&amp;pid=%3Cauthor%3EMielke%2C+Monica%3C%2Fauthor%3E%3CAN%3E2021-10357-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 56
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
Depression is a leading cause of disability among adolescents, yet existing treatments are variably effective, suggesting needs to identify novel intervention targets. Body dissatisfaction (BD) may be a promising, but understudied, target: BD is common among adolescents; prospectively associated with future depression; and modifiable through intervention. BD interventions are typically evaluated in terms of impacts on eating disorders, but many trials also measure depression-related secondary outcomes. However, BD intervention effects on depression have not been systematically examined. We, therefore, conducted a meta-analysis to estimate secondary effects of BD interventions on depression symptoms and related outcomes in adolescents (ages 12-19). 

**METHOD**
Our systematic review included randomized controlled trials (RCTs) published between January 2006 and December 2020. Across-group effect sizes were analyzed using robust variance estimation. Preregistered methods, data, and analytic code are available at https://osf.io/734n8/. RESULTS: The meta-analysis included 13 RCTs, 50 effect sizes, and 6,962 participants. BD interventions led to significant postintervention reductions in depression-related outcomes versus control conditions (g = -0.19 at postintervention, 95% confidence interval: -0.07, -0.31, p = .005). No evidence emerged for moderators of this meta-analytic effect. 

**DISCUSSION**
Overall, BD-focused interventions significantly reduced adolescent depression, with mean postintervention effect sizes comparable to those observed for interventions targeting depression explicitly. Results are bolstered by preregistered methods and robustness checks. Limitations include a lack of data on participants&#039; sexual and gender identities and a significant risk of bias in the underlying literature. Future research on BD interventions should measure depression symptom severity as a secondary outcome.
AN  - 34951477
AU  - Ahuvia,
AU  - I.
AU  - Jans,
AU  - L.
AU  - Schleider,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/eat.23659
L1  - internal-pdf://2671773608/Intl J Eating Disorders - 2021 - Ahuvia - Seco.pdf
PY  - 2021
SP  - 24
T2  - International Journal of Eating Disorders
TI  - Secondary effects of body dissatisfaction interventions on adolescent depressive symptoms: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34951477
UR  - https://onlinelibrary.wiley.com/doi/10.1002/eat.23659
VL  - 24
ER  -
TY  - JOUR
AB  - **Background**
Symptoms of autism spectrum disorder (ASD) have been associated, in part, with the dysfunction of N‐methyl‐D‐aspartate (NMDA) glutamate receptors at excitatory synapses and glutamate abnormalities. Medications related to glutamatergic neurotransmission, such as D‐cycloserine ‐ which is a partial agonist of the NMDA glutamate receptor ‐ are potential treatment options for the core features of ASD. However, the potential effect of D‐cycloserine on the social and communication skills deficits of individuals with ASD has not been thoroughly explored and no systematic reviews of the evidence have been conducted.

**Objectives**
To assess the efficacy and adverse effects of D‐cycloserine compared with placebo for social and communication skills in individuals with ASD.Search methodsIn November 2020, we searched CENTRAL, MEDLINE, Embase, six other databases and two trials registers. We also searched the reference lists of relevant publications and contacted the authors of the included study, Minshawi 2016, to identify any additional studies. In addition, we contacted pharmaceutical companies, searched manufacturers&#039; websites and sources of reports of adverse events. 

**Selection criteria**
All randomised controlled trials (RCTs) of any duration and dose of D‐cycloserine, with or without adjunct treatment, compared to placebo in individuals with ASD.

**Data collection and analysis**
Two review authors independently selected studies for inclusion, extracted relevant data, assessed the risk of bias, graded the certainty of the evidence using the GRADE approach, and analysed and evaluated the data. We provide a narrative report of the findings as only one study is included in this review.

**Main results**
We included a single RCT (Minshawi 2016) funded by the United States Department of Defense. It was conducted at two sites in the USA: Indiana University School of Medicine and Cincinnati Children&#039;s Hospital Medical Centre. In the included study, 67 children with ASD aged between 5 and 11 years were randomised to receive either 10 weeks (10 doses) of (50 mg) D‐cycloserine plus social skills training, or placebo plus social skills training. Randomisation was carried out 1:1 between D‐cycloserine and placebo arms, and outcome measures were recorded at one‐week post‐treatment. The &#039;risk of bias&#039; assessment for the included study was low for five domains and unclear for two domains.

The study (67 participants) reported low certainty evidence of little to no difference between the two groups for all outcomes measured at one week post‐treatment: social interaction impairment (mean difference (MD) 3.61 (assessed with the Social Responsiveness Scale), 95% confidence interval (CI) ‐5.60 to 12.82); social communication impairment (MD ‐1.08 (measured using the inappropriate speech subscale of the Aberrant Behavior Checklist (ABC)), 95% CI ‐2.34 to 0.18); restricted, repetitive, stereotyped patterns of behaviour (MD 0.12 (measured by the ABC stereotypy subscale), 95% CI ‐1.71 to 1.95); serious adverse events (risk ratio (RR) 1.11, 95% CI 0.94 to 1.31); non‐core symptoms of ASD (RR 0.97 (measured by the Clinical Global Impression‐Improvement scale), 95% CI 0.49 to 1.93); and tolerability of D‐cycloserine (RR 0.32 (assessed by the number of dropouts), 95% CI 0.01 to 7.68). 

**Authors&#039; conclusions**
We are unable to conclude with certainty whether D‐cycloserine is effective for individuals with ASD. This review included low certainty data from only one study with methodological issues and imprecision. The added value of this review compared to the included study is we assessed the risk of bias and evaluated the certainty of evidence using the GRADE approach. Moreover, if we find new trials in future updates of this review, we could potentially pool the data, which may either strengthen or decrease the evidence for our findings.
AU  - Aye,
AU  - S.
AU  - Z.
AU  - Ni,
AU  - H.
AU  - Sein,
AU  - H.
AU  - H.
AU  - Mon,
AU  - S.
AU  - T.
AU  - Zheng,
AU  - Q.
AU  - Wong,
AU  - Y.
AU  - K.
AU  - Y.
DA  - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013457.pub2
L1  - internal-pdf://1127419428/Aye_et_al-2021-Cochrane_Database_of_Systematic.pdf
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - The effectiveness and adverse effects of D‐cycloserine compared with placebo on social and communication skills in individuals with autism spectrum disorder
ER  -
TY  - JOUR
AB  - **CONTEXT**: Omega-3, a long-chain polyunsaturated fatty acid (LC-PUFA), may help promote healthy sleep outcomes. However, evidence from randomized controlled trials are inconclusive. 

**OBJECTIVE**: The objective of this systematic review and meta-analysis was to explore the impact of omega-3 LC-PUFA supplementation and related dietary intervention in clinical trials as well as omega-3 LC-PUFA exposure in longitudinal studies on human&#039;s sleep-related outcome. DATA SOURCES: The PubMed, EMBASE, Cochrane Library, CINAHL, and AMED databases were searched from inception to November 2019. Randomized controlled trials, clinical trials that included a control group, and longitudinal studies that reported the intake of omega-3 LC-PUFA and sleep-related outcomes were included. STUDY SELECTION: A total of 20 studies with 12 clinical trials and 8 longitudinal studies were identified for inclusion. DATA EXTRACTION: Participant characteristics, study location, intervention information, and sleep-related outcome measurements were reported. Included studies were appraised with Cochrane risk-of-bias tools and the Newcastle-Ottawa Scale. Weighted mean differences (WMDs) and 95%CIs were pooled with fixed or random effect models. 

**RESULTS**: Omega-3 LC-PUFA may improve infants&#039; sleep organization and maturity. It reduced the percentage of infants&#039; active sleep (WMD = -8.40%; 95%CI, -14.50 to -2.29), sleep-wake transition (WMD = -1.15%; 95%CI, -2.09 to -0.20), and enhanced the percentage of wakefulness (WMD = 9.06%; 95%CI, 1.53-16.59) but had no effect on quiet sleep. Omega-3 reduced children&#039;s total sleep disturbance score for those with clinical-level sleep problems (WMD = -1.81; 95%CI, -3.38 to -0.23) but had no effect on healthy children&#039;s total sleep duration, sleep latency, or sleep efficiency. No effectiveness was found in adults&#039; total sleep duration, sleep latency, sleep efficiency, sleep quality, or insomnia severity. 

**CONCLUSION**: Omega-3 LC-PUFA may improve certain aspects of sleep health throughout childhood. Additional robust studies are warranted to confirm the relationship between omega-3 LC-PUFA and sleep.
AN  - 33382879
AU  - Dai,
AU  - Y.
AU  - Liu,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/nutrit/nuaa103
L1  - internal-pdf://3847780796/Dai-2021-Omega-3 long-chain polyunsaturated fa.pdf
PY  - 2021
SP  - 847-868
T2  - Nutrition Reviews
TI  - Omega-3 long-chain polyunsaturated fatty acid and sleep: a systematic review and meta-analysis of randomized controlled trials and longitudinal studies
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33382879
UR  - https://academic.oup.com/nutritionreviews/article-abstract/79/8/847/6056631?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/nuaa103.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAvYwggLyBgkqhkiG9w0BBwagggLjMIIC3wIBADCCAtgGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMypF14-IAmgJqk8-xAgEQgIICqWjGR_4Neaa8ZQK5eUwY8M6qFWPik5ThD7-WdS20rvNQP6LqUtqrXShOgzCoiISTHpPVylND60XA-jhSRMYsLKvxpu1yPgKfU0EN03fEhMJ16YoIv3JFTSbS906u521hmEZX_NwXJtZ1Pek20amSiSycxlevA32abXZ-7tI7w_ojl7C-MKTCFu6rSZQ8JcE02Joz2A2PTpCyqlynilgsqYMPdZKeIiPk13iJZEzS1zOZIaMIgnUY3FI-0Xirh4RXkX00owdb6RKhKZ4JH9NtdyU632A0nRMM5QGpOlX6JKKwICZyRRuSs5_wcEwE440AcA4R6y3ZxCFuANVcKHaa-DP3rgJOvVotD1FAytG8JgDj2De-UdImkNw03rZh-QnuqzmblRraVk50x_KYaSuFb0lH8FYrki1EWIpIlNCe2GyL8zOTtM8UZBzNl8IaiYa5jcrz92-08_2K_JLZklc8T4g5g-T1-Emh0Tfdacbk0WYQlCoYMa8vcHXW6Bqiq0DtBV522kVNXnQ02KyDJ702wuCEC3ySBIJJwNrP7x4EtHn4eqf_FA85WSbRzHf38ph1Lp_SuLGToA2UCe9R5A51MPPWTfE68esbK8cMsslixmHodXqak_Ll1fwbSBCUfJAsGDYVtqp4I_kLjaDnp74zo-yB1N0g08Ss_OWSbKkm_KNapd-Wl4Uano6tTQIvtspKfYSFucn7GlkZpdHQbElPcrLHQ_jWwh022nG-EE5xnaolAdeLFv1xvQacKHmOE1DZtkg3DH_6Qv5RFQxj8STvcD_tGV5IN5E5JKlySmMlTcYctzmXQy9C6N2sWoMyHbooVel9d-4UwqBM4JnhcGtAJvv43vNrTWrLrVNx83EFMHAG9Uc9F6JpYjhDiUn3Lvj9Iov_zk8Qmu-rfw
VL  - 79
ER  -
TY  - JOUR
AB  - There are a variety of skills that are not directly taught in schools yet serve as protective factors for academic success (i.e., self-efficacy, social, skills; emotional well-being; Graziano et al (Journal of School Psychology 45 3-19 2007); Minnard (Children and Schools 24(4) 233-246 2002). An intervention strategy for promoting such protective factors in school-aged children involves mentoring. Despite the dramatic increase in the implementation of mentoring programs in the first decade of the current century (Herrera et al (Making a difference in schools 2007); Portwood &amp; Ayers (Children and Schools 30 177-185 2005), there remain few systematic program evaluations and even fewer meta-analyses examining the effects of mentoring. Specifically, there is a paucity of research examining the potential benefits of mentoring on emotional well-being. The current study addresses this gap in the literature by providing an overall assessment of the relationship between mentoring and emotional functioning of mentees. A qualitative analysis, as well as a quantitative meta-analysis, examining the effects of mentoring programs on the emotional well-being of school-aged children is presented. Overall, findings provide evidence for a small to moderate positive effect of mentoring on the emotional well-being of youth. Additional analyses focusing on specific emotional constructs indicate that mentoring has a small negative effect (d = 0.20) on negative affect, a medium negative effect on internalizing behavior (d = 0.45), and a medium positive effect on self-esteem (d = 0.45). For children, success in school requires more than reading, writing, and arithmetic thus, mentoring may be one approach to developing the necessary protective factors that can lead to greater success. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Perelmiter, Taryn: tperelmiter@summit-school.comPerelmiter, Taryn, tperelmiter@summit-school.comClaro, Anthony: Department of Psychology, Summit School, Quebec, CanadaPerelmiter, Taryn: Research Department, Summit School, Quebec, Canada
AN  - 2021-42785-001
AU  - Claro,
AU  - A.
AU  - Perelmiter,
AU  - T.
DA  - Apr
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40688-021-00377-2
DP  - Ovid Technologies
KW  - Emotional well-being, Mentoring, Children, Adolescents, Meta-analysis
KW  - Educational Psychology [3500]
L1  - internal-pdf://3991349305/Claro-2021.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Contemporary School Psychology
TI  - The effects of mentoring programs on emotional well-being in youth: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-42785-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs40688-021-00377-2&amp;issn=2159-2020&amp;isbn=&amp;volume=&amp;issue=&amp;spage=No&amp;pages=No+Pagination+Specified&amp;date=2021&amp;title=Contemporary+School+Psychology&amp;atitle=The+effects+of+mentoring+programs+on+emotional+well-being+in+youth%3A+A+meta-analysis.&amp;aulast=Claro&amp;pid=%3Cauthor%3EClaro%2C+Anthony%3C%2Fauthor%3E%3CAN%3E2021-42785-001%3C%2FAN%3E%3CDT%3E%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s40688-021-00377-2.pdf
ER  -
TY  - JOUR
AB  - **Context**: Acceptance and Commitment Therapy (ACT) is an emerging treatment for improving psychological well-being. 

**Objective**: To summarize research evaluating the effects of ACT on psychological well-being in children with special health care needs (SHCN) and their parents. Data Sources: An electronic literature search was conducted in PubMed, Web of Science, Ovid/EMBASE and PsycINFO (January 2000-April 2021). Study Selection: Included were studies that assessed ACT in children with SHCN (ages 0-17y) and/or parents of children with SHCN and had a comparator group. Data Extraction: Descriptive data were synthesized and presented in a tabular format, and data on relevant outcomes (e.g., depressive symptoms, stress, avoidance and fusion) were used in the meta-analyses to explore the effectiveness of ACT (administered independently with no other psychological therapy) compared to no treatment. 

**Results**: Ten studies were identified (child (7) and parent (3)). In children with SHCN, ACT was more effective than no treatment at helping depressive symptoms (standardized mean difference [SMD] = -4.27, 95% CI: -5.20, -3.34; p &lt; 0.001) and avoidance and fusion (SMD = -1.64, 95% CI: -3.24, -0.03; p = 0.05), but not stress. In parents of children with SHCN, ACT may help psychological inflexibility (SMD = -0.77, 95% CI: -1.07, -0.47; p &lt; 0.01). Limitations: There was considerable statistical heterogeneity in three of the six meta-analyses. 

**Conclusions**: There is some evidence that ACT may help with depressive symptoms in children with SHCN and psychological inflexibility in their parents. Research on the efficacy of ACT for a variety of children with SHCN and their parents is especially limited, and future research is needed.
AN  - WOS:000682009900001
AU  - Parmar,
AU  - A.
AU  - Esser,
AU  - K.
AU  - Barreira,
AU  - L.
AU  - Miller,
AU  - D.
AU  - Morinis,
AU  - L.
AU  - Chong,
AU  - Y.
AU  - E.
AU  - Y.
AU  - Smith,
AU  - W.
AU  - Major,
AU  - N.
AU  - Church,
AU  - P.
AU  - Cohen,
AU  - E.
AU  - Orkin,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph18158205
L1  - internal-pdf://2461156943/Parmar-2021-Acceptance and Commitment Therapy.pdf
PY  - 2021
SP  - 19
T2  - International Journal of Environmental Research and Public Health
TI  - Acceptance and Commitment Therapy for Children with Special Health Care Needs and Their Parents: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000682009900001
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-18-08205/article_deploy/ijerph-18-08205-v2.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - There is mixed evidence on the association between headache and attention-deficit/hyperactivity disorder (ADHD), as well as headache and ADHD medications. This systematic review and meta-analysis investigated the co-occurrence of headache in children with ADHD, and the effects of ADHD medications on headache. Embase, Medline and PsycInfo were searched for population-based and clinical studies comparing the prevalence of headache in ADHD and controls through January 26, 2021. In addition, we updated the search of a previous systematic review and network meta-analysis of double-blind randomized controlled trials (RCTs) on ADHD medications on June 16, 2020. Trials of amphetamines, atomoxetine, bupropion, clonidine, guanfacine, methylphenidate, and modafinil with a placebo arm and reporting data on headache as an adverse event, were included. Thirteen epidemiological studies and 58 clinical trials were eligible for inclusion. In epidemiological studies, a significant association between headache and ADHD was found [odds ratio (OR) = 2.01, 95% confidence interval (CI) = 1.63-2.46], which remained significant when limited to studies reporting ORs adjusted for possible confounders. The pooled prevalence of headaches in children with ADHD was 26.6%. In RCTs, three ADHD medications were associated with increased headache during treatment periods, compared to placebo: atomoxetine (OR = 1.29, 95% CI = 1.06-1.56), guanfacine (OR = 1.43, 95% CI = 1.12-1.82), and methylphenidate (OR = 1.33, 95% CI = 1.09-1.63). The summarized evidence suggests that headache is common in children with ADHD, both as part of the clinical presentation as such and as a side effect of some standard medications. Monitoring and clinical management strategies of headache in ADHD, in general, and during pharmacological treatment are recommended.
AN  - 34635194
AU  - Pan,
AU  - P.
AU  - Y.
AU  - Jonsson,
AU  - U.
AU  - Sahpazoglu
AU  - Cakmak,
AU  - S.
AU  - S.
AU  - Hage,
AU  - A.
AU  - Hohmann,
AU  - S.
AU  - Nobel
AU  - Norrman,
AU  - H.
AU  - Buitelaar,
AU  - J.
AU  - K.
AU  - Banaschewski,
AU  - T.
AU  - Cortese,
AU  - S.
AU  - Coghill,
AU  - D.
AU  - Bolte,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1017/S0033291721004141
L1  - internal-pdf://2213715554/Pan-2021-Headache in ADHD as comorbidity and a.pdf
PY  - 2021
SP  - 1-12
T2  - Psychological Medicine
TI  - Headache in ADHD as comorbidity and a side effect of medications: a systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34635194
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/86B4FF59071AE58B9730EE3D665914A8/S0033291721004141a.pdf/div-class-title-headache-in-adhd-as-comorbidity-and-a-side-effect-of-medications-a-systematic-review-and-meta-analysis-div.pdf
ER  -
TY  - JOUR
AB  - Depression and anxiety are often first experienced during childhood and adolescence, and interest in the prevention of these disorders is growing. The focus of this review was to assess the effectiveness of psychological prevention programs delivered in schools, and to provide an update to our previous review from five years ago (Werner-Seidler, Perry, Calear, Newby, &amp; Christensen, 2017). 

Three electronic databases were systematically searched for published articles of randomised controlled trials (RCTs) evaluating the efficacy of school-based prevention programs until October 2020. There were 130 articles that met inclusion criteria, representing 118 unique trials and 45,924 participants. Small between-group effect sizes for depression (g = 0.21) and anxiety (g = 0.18) were detected immediately post-intervention. 

Subgroup analyses suggested that targeted prevention programs (for young people with risk factors or symptoms) were associated with significantly greater effect sizes relative to universal programs for depression, which was confirmed by meta-regression. There was also some evidence that external providers conferred some benefit over school-staff delivered programs. 

Overall, study quality was moderate and no association between risk of bias and effect size was detected. School-delivered psychological prevention programs have small effects in reducing symptoms of depression and anxiety. Refinement of these programs, and knowledge about how they can be sustainably delivered in schools beyond the trial period is now needed for population-level preventive effects. 

Systematic Review Registration Number: PROPSERO - CRD42020188323.
AN  - 34571372
AU  - Werner-Seidler,
AU  - A.
AU  - Spanos,
AU  - S.
AU  - Calear,
AU  - A.
AU  - L.
AU  - Perry,
AU  - Y.
AU  - Torok,
AU  - M.
AU  - O&#039;Dea,
AU  - B.
AU  - Christensen,
AU  - H.
AU  - Newby,
AU  - J.
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.cpr.2021.102079
L1  - internal-pdf://2347516011/Werner-Seidler-2021-School-based depression an.pdf
PY  - 2021
SP  - 102079
T2  - Clinical Psychology Review
TI  - School-based depression and anxiety prevention programs: An updated systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34571372
VL  - 89
ER  -
TY  - JOUR
AB  - Previous research has shown that many school-based anti-bullying programs are effective. A prior meta-analysis (Gaffney, Ttofi, &amp; Farrington, 2019) found that intervention programs are effective in reducing school-bullying perpetration by approximately 19-20% and school-bullying victimization by approximately 15-16%. 

Using data from this prior meta-analysis, the aim of the current study was to examine the relationship between effectiveness estimates and specific elements of anti-bullying programs. Specific intervention components in line with a socio-ecological framework were coded as present or absent. Components were coded on the following levels: school, classroom, teacher, parent, peer, individual, and intervention. Meta-analytical subgroup comparisons analogous to ANOVA were computed to examine the relationship between the presence of specific components and the effectiveness in reducing bullying perpetration (n = 82) and victimization (n = 86). 

Results indicated that the presence of a number of intervention components (e.g., whole-school approach, anti-bullying policies, classroom rules, information for parents, informal peer involvement, and work with victims) were significantly associated with larger effect sizes for school-bullying perpetration outcomes. The presence of informal peer involvement and information for parents were associated with larger effect sizes for school-bullying victimization outcomes. Meta-regression analyses showed no significant relationship between effectiveness and the number of intervention components included in a program. 

The present report contributes to the understanding of &#039;what works&#039; in reducing school-bullying perpetration and victimization. The impact of these findings on future anti-bullying research is discussed.
AD  - Gaffney, Hannah. Institute of Criminology, University of Cambridge, UK. Electronic address: hg409@cam.ac.uk.Ttofi, Maria M. Institute of Criminology, University of Cambridge, UK.Farrington, David P. Institute of Criminology, University of Cambridge, UK.
AN  - 33715780
AU  - Gaffney,
AU  - H.
AU  - Ttofi,
AU  - M.
AU  - M.
AU  - Farrington,
AU  - D.
AU  - P.
DA  - Apr
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jsp.2020.12.002
DP  - Ovid Technologies
J2  - J Sch Psychol
L1  - internal-pdf://1309283558/Gaffney-2021.pdf
LA  - English
N1  - Gaffney, HannahTtofi, Maria MFarrington, David PS0022-4405(20)30075-3
PY  - 2021
SP  - 37-56
T2  - Journal of School Psychology
TI  - What works in anti-bullying programs? Analysis of effective intervention components
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33715780
VL  - 85
ER  -
TY  - JOUR
AB  - **Aim:** 
To assess what is known about the effectiveness of face-to-face self-management programmes designed specifically for adolescents (10-19 years) with a chronic illness. 

**Design:** 
A systematic review and synthesis without meta-analysis (SWiM). 

**Data sources:** Six international web-based reference libraries were searched with a date range of 1946 to July 2020. 

**Review method:** 
The PRISMA statement and SWiM guideline were used for reporting the methods and results. The PICO format was used to develop a focused clinical question and the eligibility criteria of our review. Quality assessment of the included studies was performed using the Cochrane Effective Practice Organisation of Care criteria. 

**Results:** 
Eight studies (four randomized controlled trials and four descriptive designs) met the inclusion criteria and were published between 2003 and 2017. 

**Results of the review:** 
Three studies demonstrated measures of illness control which showed initial improvements in adherence as a result of the interventions but failed to demonstrate sustained adherence over time. Booster sessions were identified as an effective strategy to improve adherence, but were often omitted. 

**Conclusions:** 
There is a limited body of evidence on the effectiveness of self-management programmes specifically developed for adolescents with a chronic illness, an important but under researched area. Future research lies in the development of more rigorous studies that focus on quantitative outcome measures for evaluating the effectiveness of self-management programmes to guide the development of future programmes. 

**Impact:** 
It is crucial for adolescents with a chronic illness to develop independence and the self-management skills required to effectively manage their chronic condition as they transition to adulthood. On current evidence, in planning future self-management interventions should include booster sessions. Nurses with additional training and experience have a key role in supporting adolescents with a chronic illness to develop self-management skills as they assume responsibility for their own healthcare. 

(PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-77164-003
AU  - Gauci,
AU  - J.
AU  - Bloomfield,
AU  - J.
AU  - Lawn,
AU  - S.
AU  - Towns,
AU  - S.
AU  - Steinbeck,
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/jan.14801
L1  - internal-pdf://2449089155/Gauci-2021-Effectiveness of self-management pr.pdf
PY  - 2021
SP  - 3585-3599
T2  - Journal of Advanced Nursing
TI  - Effectiveness of self-management programmes for adolescents with a chronic illness: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-77164-003
UR  - https://onlinelibrary.wiley.com/doi/10.1111/jan.14801
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jan.14801?download=true
VL  - 77
ER  -
TY  - JOUR
AB  - **Objectives**
This study aims to provide a systematic review and meta-analysis of the literature on the long-term effects of interventions addressing children&#039;s and adolescents&#039; mental health literacy and/or stigmatizing attitudes.
AN  - 34975363
AU  - Fretian,
AU  - A.
AU  - M.
AU  - Graf,
AU  - P.
AU  - Kirchhoff,
AU  - S.
AU  - Glinphratum,
AU  - G.
AU  - Bollweg,
AU  - T.
AU  - M.
AU  - Sauzet,
AU  - O.
AU  - Bauer,
AU  - U.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/ijph.2021.1604072
L1  - internal-pdf://4140734296/The Long-Term Effectiveness of Interventi-2021.pdf
PY  - 2021
SP  - 1604072
T2  - International Journal of Public Health
TI  - The Long-Term Effectiveness of Interventions Addressing Mental Health Literacy and Stigma of Mental Illness in Children and Adolescents: Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=34975363
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8714636/pdf/ijph-66-1604072.pdf
VL  - 66
ER  -
TY  - JOUR
AB  - **Objectives**: The aim of this study was to evaluate the effectiveness of behavioral smoking cessation interventions among adolescents. 

**Method(s)**: MEDLINE, CENTRAL, Embase, CINAHL, KoreaMed, and KMbase were searched from inception to June 2020. Systematic reviews (SRs) or meta-analyses of randomized controlled trials (RCTs) were initially searched to perform a rapid SR. After selecting the final SR, RCTs after the publication year of the selected SR were searched. The primary outcome was smoking status after at least 6 months of follow-up, and the secondary outcome was smoking status at 4 weeks. Two reviewers independently assessed the selected studies&#039; quality using the Cochrane risk of bias tool. The meta-analysis utilized a Mantel-Haenszel fixed-effect model reporting the relative risk (RR) and 95% confidence interval (CI). The subgroup analysis utilized Cochrane&#039;s Q. 

**Result(s)**: Thirty-two RCTs (11,637 participants) from a single SR were meta-analyzed. After 6 months of follow-up, the intervention group had significantly higher abstinence rates (RR, 1.30; 95% CI, 1.20-1.41; I2=26.46%). At 4 weeks of follow-up, the intervention group also had significantly higher abstinence rates (RR, 1.92; 95% CI, 1.49-2.47; I2=0.00%). The subgroup analysis indicated a significant difference in the abstinence rate according to the study setting and the period between intervention completion and follow-up. 

**Conclusion(s)**: This review showed that adolescent behavioral smoking cessation intervention programs significantly increased abstinence rates compared to the usual care. Copyright &copy; 2021 Korea Centers for Disease Control and Prevention. All rights reserved.
AN  - 2013525888
AU  - Choi,
AU  - Y.
AU  - Lee,
AU  - C.
AU  - M.
AU  - Cho,
AU  - B.
AU  - Lee,
AU  - E.
AU  - S.
AU  - Oh,
AU  - S.
AU  - W.
AU  - Lee,
AU  - N.
AU  - Yun,
AU  - J.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.24171/J.PHRP.2021.0018
L1  - internal-pdf://3768807885/Choi-2021-Behavioral interventions for smoking.pdf
PY  - 2021
SP  - 177-186
T2  - Osong Public Health and Research Perspectives
TI  - Behavioral interventions for smoking cessation among adolescents: A rapid review and meta-analysis for the Korea Preventive Services Task Force
UR  - http://ophrp.org/journal/view.php?doi=10.24171/j.phrp.2021.0018
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8256302/pdf/j-phrp-2021-0018.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **Aims**
To synthesise and evaluate the effectiveness of virtual reality interventions in preoperative children. Background Children consider operations as a predictable threat and stressful event. Children&#039;s anxiety before an operation increases as the time draws closer. Children could understand the operating room environment and process before the operation using virtual reality, which may reduce their anxiety before an operation. Design A systematic review and meta-analysis of randomised controlled trials following the Cochrane method were conducted. 

**Method**
CINAHL, Cochrane Library, Embase, Joanna Briggs Institute, MEDLINE and PubMed databases were searched for randomised controlled trials published before February 2021. A random-effects model meta-analysis to calculate pooled prevalence and 95% confidence intervals was performed. Conduction of the review adheres to the PRISMA checklist. 

**Results**
Of 257 articles screened, six interventions involving 529 participants aged 4-12 years were included in the analysis. All study evidence levels were B2/Level 2, the quality was medium to high on the modified Jadad scale, with a low risk of bias. The results revealed that virtual reality significantly reduced preoperative anxiety in children (SMD: -0.91, 95% CI: -1.43 to -0.39, p = .0006). Furthermore, virtual reality significantly improved children&#039;s compliance with anaesthesia (SMD: 3.49, 95% CI: 1.32 to 9.21, p = .01). 

**Conclusion**
Children who used virtual reality before an operation felt more familiar with the operating room environment and understood the preoperative preparation procedures. Virtual reality effectively reduced children&#039;s anxiety and improved their compliance with anaesthesia. Relevance to clinical practice This systematic review and meta-analysis investigated the effect of virtual reality on preoperative anxiety in children and the findings supported its positive effects. The results could provide a reference for incorporating virtual reality into preoperative preparation guidelines.
AN  - WOS:000807225100001
AU  - Chen,
AU  - Y.
AU  - J.
AU  - Wang,
AU  - C.
AU  - J.
AU  - Chen,
AU  - C.
AU  - W.
DB  - Alerts 6_2022.enl
DO  - 10.1111/jocn.16394
L1  - internal-pdf://1336786143/Journal of Clinical Nursing - 2022 - Chen - Ef.pdf
PY  - 2021
SP  - 11
T2  - Journal of Clinical Nursing
TI  - Effects of virtual reality on preoperative anxiety in children: A systematic review and meta-analysis of randomised controlled trials
UR  - &lt;Go to ISI&gt;://WOS:000807225100001
ER  -
TY  - JOUR
AB  - Interventions for attention-deficit/hyperactivity disorder (ADHD) include positive behavior supports (e.g., parent training, school-based contingency management, behavioral peer interventions), training interventions (e.g., organizational skills training, social skills training, etc.), and other interventions (e.g., academic accommodations/modifications, self-monitoring). There is a need to conduct a comprehensive meta-analysis of psychosocial treatments for ADHD given discrepancies between meta-analyses. The present meta-analysis reports the results of between-group studies that compared a psychosocial treatment to a control condition from 1968 to 2016. In total, 226 studies were identified that met inclusion criteria. Results of the meta-analysis were organized by treatment type, rater, and domain of outcome assessed. Results indicated considerable variability across these parameters, with the strongest effects for proximal outcomes of behavioral parent training (improvements in parenting behaviors yielded a standardized mean difference of 0.70) and improvements in child behavior following implementation of behavioral school intervention (standardized mean difference of 0.66 and 0.72 for teacher ratings of ADHD symptoms and impairment, respectively). Other interventions were not extensively studied as stand-alone approaches. Results are discussed in light of current support for the use of psychosocial interventions for individuals with ADHD.
AN  - WOS:000673042700001
AU  - Fabiano,
AU  - G.
AU  - A.
AU  - Schatz,
AU  - N.
AU  - K.
AU  - Aloe,
AU  - A.
AU  - M.
AU  - Pelham,
AU  - W.
AU  - E.
AU  - Smyth,
AU  - A.
AU  - C.
AU  - Zhao,
AU  - X.
AU  - Merrill,
AU  - B.
AU  - M.
AU  - Macphee,
AU  - F.
AU  - Ramos,
AU  - M.
AU  - Hong,
AU  - N.
AU  - T.
AU  - L.
AU  - Altszuler,
AU  - A.
AU  - Ward,
AU  - L.
AU  - Rodgers,
AU  - D.
AU  - B.
AU  - Liu,
AU  - Z.
AU  - J.
AU  - Ersen,
AU  - R.
AU  - K.
AU  - Coxe,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3102/00346543211025092
L1  - internal-pdf://0071142958/Fabiano-Comprehensive Meta-Analysis of Attenti.pdf
PY  - 2021
SP  - 43
T2  - Review of Educational Research
TI  - Comprehensive Meta-Analysis of Attention-Deficit/Hyperactivity Disorder Psychosocial Treatments Investigated Within Between Group Studies
UR  - &lt;Go to ISI&gt;://WOS:000673042700001
UR  - https://journals.sagepub.com/doi/10.3102/00346543211025092
UR  - https://journals.sagepub.com/doi/pdf/10.3102/00346543211025092
ER  -
TY  - JOUR
AB  - **Background**: By understanding specific differences between responders to a treatment and non-responders, treatment modalities may be fitted to the individual in order to increase effectiveness, a concept known as &quot;precision medicine&quot;. This systematic review and meta-analysis investigated which pretreatment patient and family characteristics may predict the outcome of cognitive-behavioral therapy (CBT) in clinically anxious and/or depressed youth. In particular, higher symptom severity, more severe co-occurring anxiety or depression and more severe parental psychopathology were hypothesized to predict a worse CBT outcome. 

**Methods**: The databases PubMed, PsycINFO and Cochrane Library were searched; 73 publications were included in the review from which 23 studies were used for the meta-analysis. 

**Results**: Higher symptom severity represented a clinically relevant predictor of a worse CBT outcome, with large effects estimated by meta-analysis. Further, parental psychopathology was significant and detrimental for CBT outcome in anxious but not depressed youth, while the effects for co-occurring anxiety and depression remained unclear. The additional results of the review show that only few characteristics seemed to be clearly associated with a worse CBT outcome, namely worse coping skills and, restricted to depressed patients, more non-suicidal self-injury. Limitations: The available evidence was of only moderate quality in general, further high-quality research with more transparent reporting is needed. 

**Conclusions**: The patient characteristics identified as being relevant for CBT outcome may represent important candidates for use in single patient prediction models for precision medicine in the field of child and adolescent psychotherapy. The review was preregistered on PROSPERO (ID: CRD42018116881). (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Kunas, Stefanie L.: Stefanie.Kunas@charite.deKunas, Stefanie L.: Clinic for Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, Germany, 10117, Stefanie.Kunas@charite.deKunas, Stefanie L.: Department of Psychology, Humboldt-Universitat zu Berlin, Berlin, GermanyLautenbacher, Leopold M.: Department of Psychology, Humboldt-Universitat zu Berlin, Berlin, GermanyLueken, Ulrike: Department of Psychology, Humboldt-Universitat zu Berlin, Berlin, GermanyHilbert, Kevin: Department of Psychology, Humboldt-Universitat zu Berlin, Berlin, Germany
AN  - 2020-91544-082
AU  - Kunas,
AU  - S.
AU  - L.
AU  - Lautenbacher,
AU  - L.
AU  - M.
AU  - Lueken,
AU  - U.
AU  - Hilbert,
AU  - K.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2020.09.092
DP  - Ovid Technologies
KW  - Children, adolescents, CBT, Predictor, Outcome, Depression, Anxiety
KW  - *Adolescent Psychotherapy
KW  - *Anxiety Disorders
KW  - *Child Psychotherapy
KW  - *Cognitive Behavior Therapy
KW  - *Major Depression
KW  - Cognitive Therapy [3311]
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://4162657603/Kunas-2021.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2021
SP  - 614-626
T2  - Journal of Affective Disorders
TI  - Psychological predictors of cognitive-behavioral therapy outcomes for anxiety and depressive disorders in children and adolescents: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-91544-082
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jad.2020.09.092&amp;issn=0165-0327&amp;isbn=&amp;volume=278&amp;issue=&amp;spage=614&amp;pages=614-626&amp;date=2021&amp;title=Journal+of+Affective+Disorders&amp;atitle=Psychological+predictors+of+cognitive-behavioral+therapy+outcomes+for+anxiety+and+depressive+disorders+in+children+and+adolescents%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Kunas&amp;pid=%3Cauthor%3EKunas%2C+Stefanie+L%3C%2Fauthor%3E%3CAN%3E2020-91544-082%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 278
ER  -
TY  - JOUR
AB  - **Objective**: To assess the relative efficacy and safety of second-generation antipsychotics for treating major depressive episodes in youths with bipolar disorder. 

**Method(s)**: A systematic literature review using PRISMA guidelines and network meta-analysis (NMA) of randomized controlled trials (RCTs) of second-generation antipsychotics for bipolar depression in youths 10 to 18 years of age was conducted. Efficacy measures included Children&#039;s Depression Rating Scale, Revised (CDRS-R) and Clinical Global Impressions-Bipolar Disorder-Severity Depression (CGI-BP-S-depression) and Overall (CGI-BP-S-overall) scores. Available safety outcomes included discontinuations (all-cause, lack of efficacy, adverse events), metabolic parameters (weight change, cholesterol, triglycerides, glucose), changes in prolactin, and somnolence. Results from the NMA were reported as mean changes from baseline or odds ratios (OR) with 95% credible intervals (CrIs). 

**Result(s)**: Four RCTs comparing placebo to lurasidone, quetiapine (1 each for immediate- and extended-release), and the olanzapine-fluoxetine combination (OFC) met all of the inclusion criteria. Lurasidone and OFC demonstrated similar and statistically significant improvements in CDRS-R, but quetiapine did not (lurasidone: -5.70 [-8.66, -2.76]; OFC: -5.01 [-8.63, -1.38]; quetiapine: -1.85 [-5.99, 2.27]). Lurasidone was associated with smaller changes in weight, cholesterol, and triglycerides from baseline compared to OFC and quetiapine. There were no differences in changes in glucose levels among antipsychotics. In addition, lurasidone was associated with smaller change in prolactin levels compared to OFC but not quetiapine. 

**Conclusion(s)**: Evidence from 4 studies in this NMA indicated that lurasidone and OFC, but not quetiapine, were efficacious for the treatment of bipolar depression in youths. Lurasidone was associated with less weight gain and smaller impacts on cholesterol and triglycerides compared with quetiapine and OFC. Copyright &copy; 2021 American Academy of Child and Adolescent Psychiatry
AN  - 2014169344
AU  - DelBello,
AU  - M.
AU  - P.
AU  - Kadakia,
AU  - A.
AU  - Heller,
AU  - V.
AU  - Singh,
AU  - R.
AU  - Hagi,
AU  - K.
AU  - Nosaka,
AU  - T.
AU  - Loebel,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jaac.2021.03.021
L1  - internal-pdf://3184996360/DelBello-2021-Systematic Review and Network Me.pdf
PY  - 2021
T2  - Journal of the American Academy of Child and Adolescent Psychiatry.
TI  - Systematic Review and Network Meta-analysis: Efficacy and Safety of Second-Generation Antipsychotics in Youths With Bipolar Depression
UR  - http://www.jaacap.com
ER  -
TY  - JOUR
AB  - Insufficient sleep duration is detrimental to health and performance and is alarmingly common in adolescents and young adults. 

The aim of this pre-registered meta-analysis was to determine the feasibility of at-home sleep extension as a means to improve sleep duration and daytime sleepiness, and maintain or improve sleep quality and efficiency, in adolescents and young adults. Peer-reviewed journal articles and dissertations were screened to identify studies with at least five consecutive days of at-home sleep extension, pre- and post-extension measurement of sleep duration, and participants 13-30 years of age. 

Out of 2254 studies assessed for eligibility, 17 met review inclusion criteria - seven in adolescents and ten in young adults. At-home extension of sleep opportunity reliably increased sleep duration and sleep quality, and decreased daytime sleepiness when compared to unmanipulated sleep opportunity. These results indicate that at-home sleep extension is feasible in adolescents and young adults. However, the degree of improvement in sleep duration, sleep quality, and daytime sleepiness varied by study population and sleep extension method, which will have downstream consequences for the effectiveness of sleep extension as an experimental manipulation and intervention to improve health and performance during adolescence and young adulthood. (C) 2021 Elsevier Ltd. All rights reserved.
AN  - WOS:000680163800009
AU  - Niu,
AU  - X.
AU  - R.
AU  - Zhou,
AU  - S.
AU  - J.
AU  - Casement,
AU  - M.
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.smrv.2021.101443
L1  - internal-pdf://3677176392/Niu-2021-The feasibility of at-home sleep exte.pdf
N1  - Ingrid Borren (2021-09-15 22:05:45)(Screen): i tvil;
PY  - 2021
SP  - 11
T2  - Sleep Medicine Reviews
TI  - The feasibility of at-home sleep extension in adolescents and young adults: A meta-analysis and systematic review
UR  - &lt;Go to ISI&gt;://WOS:000680163800009
VL  - 58
ER  -
TY  - JOUR
AB  - **METHODS**: We searched seven databases and found 13 eligible controlled trials that use omega-3 supplementation in children and adolescents with ASD. <b>Data extraction:</b> We collected details on study design, intervention time, supplement dosage, and the autism assessment scale. Meta-analyses and subgroup analysis were conducted according to the autism symptoms.

**RESULTS**: Omega-3 and omega-6 supplementation improved ASD symptoms according to the Aberrant Behavior Checklist (standard mean difference - SMD = -0.13; CI 95% = -0.34, -0.02). However, using subgroup analysis, we observed no efficacy in terms of improvements in hyperactivity (SMD = -0.03; CI 95%: -0.43, 0.36), irritability (SMD = -0.18; CI 95%: -0.51, 0.15), stereotypy (SMD = -0.03; CI 95%: -0.43, 0.36), inappropriate speech (SMD = -0.68; CI 95%: -1.49, 0.14), lethargy (SMD = -0.22; CI 95%: -0.58, 0.14), and social function (SMD = -0.71; IC 95%: -1.56, 0.14). W-3 and w-6 supplementation also showed no efficacy according to the Social Responsiveness Scale (SMD = 0.08; CI 95%: -0.23, 0.39). The adverse effects were classified as mild and equally distributed between the placebo and intervention groups.

**CONCLUSIONS**: Despite w-3 and w-6 supplementation showing minimal beneficial effects in the treatment of autism, the subgroup analyses indicated that there is a lack of evidence on the beneficial role of w-3 and w-6 in treating ASD.
Systematic Review Registration: PROSPERO number CRD42020146116.
AD  - de Andrade Wobido, Kelma. Center for Biological and Health Sciences, Federal University of Western Bahia, Barreiras, Brazil.de Sa Barreto da Cunha, Marcela. Center for Biological and Health Sciences, Federal University of Western Bahia, Barreiras, Brazil.Miranda, Samilly Silva. Institute of Collective Health, Federal University of Bahia, Salvador, Bahia.da Mota Santana, Jerusa. Health Sciences Center, Federal University of Reconcavo da Bahia, Santo Antonio de Jesus, Bahia.da Silva, Danielle Cristina Guimaraes. Center for Biological and Health Sciences, Federal University of Western Bahia, Barreiras, Brazil.Pereira, Marcos. Institute of Collective Health, Federal University of Bahia, Salvador, Bahia.
AN  - 33871323
AU  - de
AU  - Andrade
AU  - Wobido,
AU  - K.
AU  - de
AU  - Sa
AU  - Barreto
AU  - da
AU  - Cunha,
AU  - M.
AU  - Miranda,
AU  - S.
AU  - S.
AU  - da
AU  - Mota
AU  - Santana,
AU  - J.
AU  - da
AU  - Silva,
AU  - D.
AU  - C.
AU  - G.
AU  - Pereira,
AU  - M.
DA  - Apr 19
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/1028415X.2021.1913950
DP  - Ovid Technologies
J2  - Nutr Neurosci
L1  - internal-pdf://0104544678/de Andrade Wobido-2021.pdf
LA  - English
N1  - de Andrade Wobido, Kelmade Sa Barreto da Cunha, MarcelaMiranda, Samilly Silvada Mota Santana, Jerusada Silva, Danielle Cristina GuimaraesPereira, Marcos
PY  - 2021
SP  - 1-13
T2  - Nutritional Neuroscience
TI  - Non-specific effect of omega-3 fatty acid supplementation on autistic spectrum disorder: systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33871323
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33871323&amp;id=doi:10.1080%2F1028415X.2021.1913950&amp;issn=1028-415X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-13&amp;date=2021&amp;title=Nutritional+Neuroscience&amp;atitle=Non-specific+effect+of+omega-3+fatty+acid+supplementation+on+autistic+spectrum+disorder%3A+systematic+review+and+meta-analysis.&amp;aulast=de+Andrade+Wobido&amp;pid=%3Cauthor%3Ede+Andrade+Wobido+K%3C%2Fauthor%3E%3CAN%3E33871323%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/full/10.1080/1028415X.2021.1913950
UR  - https://www.tandfonline.com/doi/pdf/10.1080/1028415X.2021.1913950?needAccess=true
ER  -
TY  - JOUR
AB  - **INTRODUCTION AND OBJECTIVES:**
To conduct a systematic literature review of intervention programs designed to promote healthy romantic relationships in youth (aged 12-25 years). The focus was on universal interventions that have the potential to be effective and widely implemented. 

**METHODS: **
We systematically searched PubMed, PsycINFO, Social Science Database, and Embase. Articles were included if they were a randomized controlled trial (RCT) or quasi-experimental study and reported on a universal intervention aimed at promoting healthy romantic relationship knowledge, attitudes, and behaviors among youth. 

**RESULTS: **
The search strategy identified 27 studies (26,212 participants). Interventions were found to be effective for improving healthy romantic relationship knowledge in the target population. However, the findings were mixed for intervention effectiveness in changing relationship attitudes/beliefs, and there was limited evidence to support change across behavioral outcomes. 

**CONCLUSIONS: **
This review highlights the need for future research, including high quality RCTs with longer follow-up periods in a broad range of cultural and ethnic settings, to improve the generalisability of findings. Interventions for adolescents that improve knowledge and behavioral change relating to healthy romantic relationships have the potential to reduce mental and physical health problems during this phase of development.
AN  - 34583269
AU  - Hielscher,
AU  - E.
AU  - Moores,
AU  - C.
AU  - Blenkin,
AU  - M.
AU  - Jadambaa,
AU  - A.
AU  - Scott,
AU  - J.
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.adolescence.2021.08.008
L1  - internal-pdf://2312446704/Hielscher-2021-Intervention programs designed.pdf
PY  - 2021
SP  - 194-236
T2  - Journal of Adolescence
TI  - Intervention programs designed to promote healthy romantic relationships in youth: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34583269
VL  - 92
ER  -
TY  - JOUR
AB  - **OBJECTIVE**: The present systematic review and dose-response meta-analysis was conducted to quantify the efficacy of zinc supplementation on clinical symptoms of attention-deficit/hyperactivity disorder (ADHD) in children. 

**METHODS**: Electronic databases including PubMed, Scopus, ISI web of science, and Google Scholar were searched until January 2021. Results were reported as standardized mean difference (SMD) with a 95% confidence interval (CI) using Hedges&#039;s adjusted g method. 

**RESULTS**: six randomized clinical trials with 489 school-aged children were identified for the meta-analysis. Our findings showed a significant effect of zinc supplementation on ADHD total scores (SMD: -0.62 Hedges&#039; g; 95% CI: -1.24 to -0.002, p = 0.04) but not in hyperactivity scores (SMD: -0.93 Hedges&#039; g; 95% CI: -3.31 to 1.45, p = 0.44) and inattention scores (SMD: 0.21 Hedges&#039; g; 95% CI: -0.09 to 0.51, p = 0.17) compared to the control group. Besides, the dose-response analysis did not find any significant non-linear association between zinc supplementation dosage or duration on ADHD total scores. The certainty of the evidence was rated moderate to very low for all outcomes. 

**CONCLUSION**: Zinc supplementation may have beneficial effects in improving ADHD symptoms in children with ADHD. Future well-designed, large-scale randomized controlled trials are needed to establish the benefit of zinc supplementation for ADHD.
AN  - 34184967
AU  - Talebi,
AU  - S.
AU  - Miraghajani,
AU  - M.
AU  - Ghavami,
AU  - A.
AU  - Mohammadi,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/10408398.2021.1940833
L1  - internal-pdf://3980781480/Talebi-2021-The effect of zinc supplementation.pdf
PY  - 2021
SP  - 1-10
T2  - Critical Reviews in Food Science &amp; Nutrition
TI  - The effect of zinc supplementation in children with attention deficit hyperactivity disorder: A systematic review and dose-response meta-analysis of randomized clinical trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34184967
UR  - https://www.tandfonline.com/doi/full/10.1080/10408398.2021.1940833
UR  - https://www.tandfonline.com/doi/pdf/10.1080/10408398.2021.1940833?needAccess=true
ER  -
TY  - JOUR
AB  - **Background**
Insufficient physical activity is one of four primary risk factors for non‐communicable diseases such as stroke, heart disease, type 2 diabetes, cancer and chronic lung disease. As few as one in five children aged 5 to 17 years have the physical activity recommended for health benefits. The outside‐school hours period contributes around 30% of children&#039;s daily physical activity and presents a key opportunity for children to increase their physical activity. Testing the effects of interventions in outside‐school hours childcare settings is required to assess the potential to increase physical activity and reduce disease burden.

**Objectives**
To assess the effectiveness, cost‐effectiveness and associated adverse events of interventions designed to increase physical activity in children aged 4 to 12 years in outside‐school hours childcare settings.

**Search methods**
We searched CENTRAL, MEDLINE, Embase, ERIC and SportsDISCUS to identify eligible trials on 18 August 2020. We searched two databases, three trial registries, reference lists of included trials and handsearched two physical activity journals in August 2020. We contacted first and senior authors on articles identified for inclusion for ongoing or unpublished potentially relevant trials in August 2020.

**Selection criteria**
We included randomised controlled trials, including cluster‐randomised controlled trials, of any intervention primarily aimed at increasing physical activity in children aged 4 to 12 years in outside‐school hours childcare settings compared to usual care. To be eligible, the interventions must have been delivered in the context of an existing outside‐school hours childcare setting (i.e. childcare that was available consistently throughout the school week/year), and not set up in the after‐school period for the purpose of research. Two review authors independently screened titles and abstracts of identified papers with discrepancies resolved via a consensus discussion. A third review author was not required to resolve disagreements.

**Data collection and analysis**
Two review authors independently extracted data and assessed the risk of bias of included trials with discrepancies resolved via a consensus discussion; a third review author was not required to resolve disagreements. For continuous measures of physical activity, we reported the mean difference (MD) with 95% confidence intervals (CIs) in random‐effects models using the generic inverse variance method for each outcome. For continuous measures, when studies used different scales to measure the same outcome, we used standardised mean differences (SMDs). We conducted assessments of risk of bias of all outcomes and evaluated the certainty of evidence (GRADE approach) using standard Cochrane procedures.

**Main results**
We included nine trials with 4458 participants. Five trials examined the effectiveness of staff‐based interventions to change practice in the outside‐school hours childcare setting (e.g. change in programming, activities offered by staff, staff facilitation/training). Two trials examined the effectiveness of staff‐ and parent‐based interventions (e.g. parent newsletters/telephone calls/messages or parent tool‐kits in addition to staff‐based interventions), one trial assessed staff‐ and child‐based intervention (e.g. children had home activities to emphasise physical activity education learnt during outside‐school hours childcare sessions in addition to staff‐based interventions) and one trial assessed child‐only based intervention (i.e. only children were targeted). 

We judged two trials as free from high risk of bias across all domains. Of those studies at high risk of bias, it was across domains of randomisation process, missing outcome data and measurement of the outcome.

There was low‐certainty evidence that physical activity interventions may have little to no effect on total daily moderate‐to‐vigorous physical activity compared to no intervention (MD 1.7 minutes, 95% CI &ndash;0.42 to 3.82; P = 0.12; 6 trials; 3042 children). We were unable to pool data on proportion of the OSHC session spent in moderate‐to‐vigorous physical activity in a meta‐analysis. Both trials showed an increase in proportion of session spent in moderate‐to‐vigorous physical activity (moderate‐certainty evidence) from 4% to 7.3% of session time; however, only one trial was statistically significant. There was low‐certainty evidence that physical activity interventions may lead to little to no reduction in body mass index (BMI) as a measure of cardiovascular health, compared to no intervention (SMD &ndash;0.17, 95% CI &ndash;0.44 to 0.10; P = 0.22; 4 trials, 1684 children). Physical activity interventions that were delivered online were more cost‐effective than in person. Combined results suggest that staff‐and‐parent and staff‐and‐child‐based interventions may lead to a small increase in overall daily physical activity and a small reduction or no difference in BMI. Process evaluation was assessed differently by four of the included studies, with two studies reporting improvements in physical activity practices, one reporting high programme satisfaction and one high programme fidelity. The certainty of the evidence for these outcomes was low to moderate. Finally, there was very low‐certainty evidence that physical activity interventions in outside‐school hours childcare settings may increase cardiovascular fitness.

No trials reported on quality of life or adverse outcomes. Trials reported funding from local government health grants or charitable funds; no trials reported industry funding.

**Authors&#039; conclusions**
Although the review included nine trials, the evidence for how to increase children&#039;s physical activity in outside‐school hours care settings remains limited, both in terms of certainty of evidence and magnitude of the effect. Of the types of interventions identified, when assessed using GRADE there was low‐certainty evidence that multi‐component interventions, with a specific physical activity goal may have a small increase in daily moderate‐to‐vigorous physical activity and a slight reduction in BMI. There was very low‐certainty evidence that interventions increase cardiovascular fitness. By contrast there was moderate‐certainty evidence that interventions were effective for increasing proportion of time spent in moderate‐to‐vigorous physical activity, and online training is cost‐effective.
AN  - CD013380
AU  - Virgara,
AU  - R.
AU  - Phillips,
AU  - A.
AU  - Lewis,
AU  - L.
AU  - K.
AU  - Baldock,
AU  - K.
AU  - Wolfenden,
AU  - L.
AU  - Ferguson,
AU  - T.
AU  - Richardson,
AU  - M.
AU  - Okely,
AU  - A.
AU  - Beets,
AU  - M.
AU  - Maher,
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1002/14651858.CD013380.pub2
N1  - [Public Health]
PY  - 2021
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions in outside‐school hours childcare settings for promoting physical activity amongst schoolchildren aged 4 to 12 years
UR  - http://dx.doi.org/10.1002/14651858.CD013380.pub2
ER  -
TY  - JOUR
AB  - Blood loss in the first days of life has been associated with increased morbidity and mortality in very preterm infants. In this systematic review we included randomized controlled trials comparing the effects of interventions to preserve blood volume in the infant from birth, reduce the need for sampling, or limit the blood sampled. Mortality and major neurodevelopmental disabilities were the primary outcomes. Included studies underwent risk of bias-assessment and data extraction by two review authors independently. We used risk ratio or mean difference to evaluate the treatment effect and meta-analysis for pooled results. The certainty of evidence was assessed using GRADE. We included 31 trials enrolling 3,759 infants. Twenty-five trials were pooled in the comparison delayed cord clamping or cord milking vs. immediate cord clamping or no milking. Increasing placental transfusion resulted in lower mortality during the neonatal period (RR 0.51, 95% CI 0.26 to 1.00; participants = 595; trials = 5; I-2 = 0%, moderate certainty of evidence) and during first hospitalization (RR 0.70, 95% CI 0.51, 0.96; 10 RCTs, participants = 2,476, low certainty of evidence). The certainty of evidence was very low for the other primary outcomes of this review. The six remaining trials compared devices to monitor glucose levels (three trials), blood sampling from the umbilical cord or from the placenta vs. blood sampling from the infant (2 trials), and devices to reintroduce the blood after analysis vs. conventional blood sampling (1 trial); the certainty of evidence was rated as very low for all outcomes in these comparisons. Increasing placental transfusion at birth may reduce mortality in very preterm infants; However, extremely limited evidence is available to assess the effects of other interventions to reduce blood loss after birth. In future trials, infants could be randomized following placental transfusion to different blood saving approaches.
AN  - WOS:000617531400008
AU  - Persad,
AU  - E.
AU  - Sibrecht,
AU  - G.
AU  - Ringsten,
AU  - M.
AU  - Karlelid,
AU  - S.
AU  - Romantsik,
AU  - O.
AU  - Ulinder,
AU  - T.
AU  - do
AU  - Nascimento,
AU  - I.
AU  - J.
AU  - B.
AU  - Bjorklund,
AU  - M.
AU  - Arno,
AU  - A.
AU  - Bruschettini,
AU  - M.
DA  - FEB 8
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0246353
L1  - internal-pdf://2236834309/Persad-2021-Interventions to minimize blood lo.pdf
PY  - 2021
T2  - PLOS ONE
TI  - Interventions to minimize blood loss in very preterm infants-A systematic review and meta-analysis
UR  - https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0246353/1/pone.0246353.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&amp;X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210715%2Fauto%2Fstorage%2Fgoog4_request&amp;X-Goog-Date=20210715T095240Z&amp;X-Goog-Expires=86400&amp;X-Goog-SignedHeaders=host&amp;X-Goog-Signature=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
VL  - 16
ER  -
TY  - JOUR
AB  - Difficulties in applying emotional regulation (ER) skills are associated with depression and anxiety symptoms, and are common targets of treatment. 

This meta-analysis examined whether improvements in ER skills were associated with psychological treatment outcomes for depression and/or anxiety in youth. A multivariate, random-effects meta-analysis was run using metafor in R. 

Inclusion criteria included studies that were randomized controlled trials (RCTs) of a psychological intervention for depression and/or anxiety in patients aged 14-24, were peer reviewed, were written in English, measured depression and/or anxiety symptoms as an outcome and measured ER as an outcome. 

Medline, Embase, APA PsycInfo, CINAHL and The Cochrane Library were searched up to 26 June 2020. Risk of bias (ROB) was assessed using the Cochrane Collaboration Risk of Bias 2.0 tool. 

The meta-analysis includes 385 effect sizes from 90 RCTs with total N = 11,652. Psychological treatments significantly reduced depression, anxiety, emotion dysregulation (k = 13, Hedges&#039; g = 0.54, P &lt; 0.001, 95% confidence interval (CI) = 0.30-0.78) and disengagement ER (k = 83, g = 0.24, 95% CI = 0.15-0.32, P &lt; 0.001); engagement ER also increased (k = 82, g = 0.26, 95% CI = 0.15-0.32, P &lt; 0.001). 

Improvements in depression and anxiety were positively associated with improved engagement ER skills, reduced emotion dysregulation and reduced disengagement ER skills. 

Sensitivity considered study selection and publication bias. Longer treatments, group formats and cognitive-behavioural orientations produced larger positive associations between improved ER skills and reduced symptoms. 

ER skill improvement is linked to depression and anxiety across a broad range of interventions for youth. 

Limitations of the current study include reliance on self-report measures, content overlap between variables and inability to test the directionality of associations.
AN  - 34545236
AU  - Daros,
AU  - A.
AU  - R.
AU  - Haefner,
AU  - S.
AU  - A.
AU  - Asadi,
AU  - S.
AU  - Kazi,
AU  - S.
AU  - Rodak,
AU  - T.
AU  - Quilty,
AU  - L.
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1038/s41562-021-01191-9
L1  - internal-pdf://2475696193/Daros-2021-A meta-analysis of emotional regula.pdf
PY  - 2021
SP  - 20
T2  - Nature Human Behaviour
TI  - A meta-analysis of emotional regulation outcomes in psychological interventions for youth with depression and anxiety
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34545236
UR  - https://www.nature.com/articles/s41562-021-01191-9.pdf
VL  - 20
ER  -
TY  - JOUR
AB  - **Background**: An estimated 1 in 5 adolescents experience a mental health disorder each year; yet because of barriers to accessing and seeking care, most remain undiagnosed and untreated. Furthermore, the early emergence of psychopathology contributes to a lifelong course of challenges across a broad set of functional domains, so addressing this early in the life course is essential. With increasing digital connectivity, including in low- and middle-income countries, digital health technologies are considered promising for addressing mental health among adolescents and young people. In recent years, a growing number of digital health interventions, including more than 2 million web-based mental health apps, have been developed to address a range of mental health issues. 

**Objective**: This review aims to synthesize the current evidence on digital health interventions targeting adolescents and young people with mental health conditions, aged between 10-24 years, with a focus on effectiveness, cost-effectiveness, and generalizability to low-resource settings (eg, low- and middle-income countries). Methods: We searched MEDLINE, PubMed, PsycINFO, and Cochrane databases between January 2010 and June 2020 for systematic reviews and meta-analyses on digital mental health interventions targeting adolescents and young people aged between 10-24 years. Two authors independently screened the studies, extracted data, and assessed the quality of the reviews. 

**Results**: In this systematic overview, we included 18 systematic reviews and meta-analyses. We found evidence on the effectiveness of computerized cognitive behavioral therapy on anxiety and depression, whereas the effectiveness of other digital mental health interventions remains inconclusive. Interventions with an in-person element with a professional, peer, or parent were associated with greater effectiveness, adherence, and lower dropout than fully automatized or self-administered interventions. Despite the proposed utility of digital interventions for increasing accessibility of treatment across settings, no study has reported sample-specific metrics of social context (eg, socioeconomic background) or focused on low-resource settings. 

**Conclusions**: Although digital interventions for mental health can be effective for both supplementing and supplanting traditional mental health treatment, only a small proportion of existing digital platforms are evidence based. Furthermore, their cost-effectiveness and effectiveness, including in low- and middle-income countries, have been understudied. Widespread adoption and scale-up of digital mental health interventions, especially in settings with limited resources for health, will require more rigorous and consistent demonstrations of effectiveness and cost-effectiveness vis-a-vis the type of service provided, target population, and the current standard of care.
AN  - WOS:000645308300001
AU  - Lehtimaki,
AU  - S.
AU  - Martic,
AU  - J.
AU  - Wahl,
AU  - B.
AU  - Foster,
AU  - K.
AU  - T.
AU  - Schwalbe,
AU  - N.
DA  - APR 29
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/25847
L1  - internal-pdf://1125801642/Lehtimaki-2021-Evidence on Digital Mental Heal.pdf
PY  - 2021
T2  - JMIR MENTAL HEALTH
TI  - Evidence on Digital Mental Health Interventions for Adolescents and Young People: Systematic Overview
VL  - 8
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
A previous systematic review showed that intramuscular vitamin A supplementation reduced the risk of bronchopulmonary dysplasia (BPD) in very-low-birth-weight (VLBW) infants. However, more recent studies have questioned this finding. 

**OBJECTIVES: **
Our objective was to synthesize current evidence on vitamin A supplementation in very-preterm (&lt;32 wk gestational age) or VLBW infants and investigate the factors that may modify its efficacy. 

**METHODS: **
A systematic review was conducted using the Cochrane systematic review methodology. We included randomized controlled trials investigating vitamin A supplementation for reducing morbidity and mortality in very-preterm or VLBW infants. Certainty of evidence was assessed using Grading of Recommendations, Assessment, Development and Evaluation (GRADE) recommendations. Prespecified subgroup analyses assessed factors that may modify the effects of vitamin A supplementation. 

**RESULTS: **
We included 17 studies (n = 2471) in the qualitative and 15 studies (n = 2248) in the quantitative synthesis. Moderate-certainty evidence suggested a beneficial effect of vitamin A for decreasing the risk of BPD at 36 wk postmenstrual age (RR: 0.83; 95% CI: 0.74, 0.93; numbers needed to treat for an additional beneficial outcome: 16; 95% CI: 9, 53; 9 studies, n = 1752; P = 0.002). Subgroup analysis suggested that the beneficial effect was limited to infants with baseline vitamin A intake &lt;1500 IU . kg-1 . d-1. Both enteral and parenteral routes were effective. Vitamin A supplementation did not have adverse effects and did not alter mortality before discharge (12 studies, n = 1917) or neurodevelopmental outcomes at 18-22 mo (1 study, n = 538). 

**CONCLUSIONS: **
The benefit of vitamin A supplementation for reducing BPD is likely to be limited to infants with baseline vitamin A intake &lt;1500 IU . kg-1 . d-1 and is not affected by the route of administration.
AN  - 34582542
AU  - Rakshasbhuvankar,
AU  - A.
AU  - A.
AU  - Pillow,
AU  - J.
AU  - J.
AU  - Simmer,
AU  - K.
AU  - N.
AU  - Patole,
AU  - S.
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1093/ajcn/nqab294
L1  - internal-pdf://3202757264/Rakshasbhuvanka-2021-Vitamin A supplementation.pdf
PY  - 2021
SP  - 28
T2  - American Journal of Clinical Nutrition
TI  - Vitamin A supplementation in very-preterm or very-low-birth-weight infants to prevent morbidity and mortality: a systematic review and meta-analysis of randomized trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34582542
UR  - https://academic.oup.com/ajcn/advance-article-abstract/doi/10.1093/ajcn/nqab294/6377470?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/nqab294.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAuwwggLoBgkqhkiG9w0BBwagggLZMIIC1QIBADCCAs4GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMYbdWSrpmoj-MtY5XAgEQgIICnzpUePnTi753XMzOGHzQ8WnBIfOiqBNBnSk2QCr0btjKmYQI-pOloONAaeWP8mxukD1CLJOvghAyGmFruay3Ya_h3Aytw6nHjUFcgMNXkWujEGxp90TarKMn44m9VcG-V7e33fJtoZGy7Pd60QloySFGTU5eh_5STtqAfFkD5yIrVJKViFk-tDdUZpUTSZ1AO91W8BlWeLYgJo5skOgeuGXk-l70PWfvqXGnx1tYh5Lmwa7dT1z_rIoQMoR5MDi8Jzd7aGzXOj2J2NKML1r6nzCAYJuyRmxwGDw2rpxucH9o6RDOe86Xaxst8EPo5NJ3wWx4Idy9J-eyZhtep4-9LGyxm2ASCovkHzvqmxjKRWaXf2vc6dfJVj_cE3smOTEPioHEe1w6q4yLNszE_v53xjQO55nVsUmfcr-cRudU6_tL2b9HlykBJfOz5HKjNNG48RnU9HrLMQx24KviM3EAQcv2cEXMbrz_RoiMP2rNCSNLV0rwSMvSJ5QvcIZ3iDoKTMlchulQIkeiHluOMCf95hggpTtS6xFMLPC4jntMQksVAx5V8oO0A-w5ANQoiCiLQ8Fu5YliNPfTBVVQpP_6P6ajVhoCkog8lICgozNvIbjZq7v39f7wJSBCqKsrhMB4P9MWMY4m3dsf9FobpaNGQayiQawgV3qKdHYS1rHXRTYbbaTBS2CK3ZBqnmd6CzNiKlLzjYNaBXWM7ZvMCwUm3hljIoO_HbkyXtRMAWvgsgc9XJJzD2M8VrVFaCcLBTEs2Uq0Lx2H41DHs3TO9Nyni4CzzZPlo5ew5NKQAF5Fx0LGl1tMltmkyqSlP6qwsxY7GWnk0rVKy1CeZUdVN7QvOz_QzJwpGDhbtMkLcKKS_Kkff-kdQvNiJZIA9aGRliwW
VL  - 28
ER  -
TY  - GEN
AB  - **Innledning**
Kunnskapsgrunnlaget for legemidler med antipsykotisk effekt er i hovedsak basert på studier hvor pasientene mottar disse legemidlene frivillig. I praksis forekommer også bruk av antipsykotika i behandling uten pasientens samtykke (tvangsbehandling).  Det er et mangelfullt kunnskapsgrunnlag for hvorvidt antipsykotika gitt som tvangsbehandling har den samme effekten som når legemidlene tas frivillig.
Formålet med denne systematiske oversikten er å oppsummere forskning om effekt av antipsykotika ved behandling uten pasientens samtykke (tvangsbehandling) sammenlignet med frivillig behandling med antipsykotika hos personer over 16 år med psykoselidelser.
  

**Metode**
Vi har utarbeidet en systematisk oversikt ved hjelp av framgangsmåter som beskrevet i Folkehelseinstituttets metodebok for oppsummert forskning og i en fagfellevurdert prosjektplan. For å identifisere relevante studier søkte en bibliotekar i åtte internasjonale litteraturdatabaser, slik som MEDLINE, EMBASE og PsycINFO, i desember 2020. Vi søkte også i Google, skandinaviske bibliotekkataloger og gjennomgikk referanselistene til studier lest i fulltekst. Vi identifiserte ingen studier publisert etter 2010 som møtte våre inklusjonskriterier, men &eacute;n studie publisert før 2010 som var relevant når vi gjennomgikk referanselistene til studier lest i fulltekst. I februar 2021 gjennomførte vi derfor et nytt litteratursøk og inkluderte studier uten begrensninger på publikasjonsår.
Vi inkluderte kontrollerte studier (studier med en sammenligningsgruppe), som undersøkte effekten av tvangsbehandling med antipsykotika sammenlignet med frivillig behandling med antipsykotika hos personer over 16 år med psykoselidelser. Utfallene vi ønsket å måle var: endringer i psykosesymptomer, bivirkninger (alvorlige hendelser), reinnleggelse, livskvalitet, funksjonsendring i sosiale relasjoner eller arbeid.
To medarbeidere valgte uavhengig av hverandre ut relevante studier og vurderte deretter risiko for systematiske skjevheter i de inkluderte studiene (dette ble gjort ved bruk av sjekkliste for kohortstudier). Videre hentet to medarbeidere ut relevant data og oppsummerte resultatene i tekst og Tabeller. Vi beregnet effektestimater for relevante utfall rapportert i de inkluderte studiene, der det lot seg gjøre. Vi vurderte tillit til resultatene ved hjelp av GRADE-tilnærmingen.

**Resultat**
De to litteratursøkene og søket etter grå litteratur resulterte i 7601 referanser. Vi inkluderte to observasjonsstudier; &eacute;n retrospektiv kohortstudie fra USA med 102 deltakere publisert i 1991 og &eacute;n tysk prospektiv kohortstudie med 88 deltakere fra 2004. Settingen for begge studiene var døgnbehandling på institusjon, og studiene sammenlignet pasienter som ble tvangsbehandlet med frivillige behandlede pasienter. Studiene målte psykosesymptomer, reinnleggelse og fungering. I tillegg målte de andre utfall som ikke var relevante for vår problemstilling.
De inkluderte studiene hadde begge høy risiko for systematiske skjevheter, da gruppene ikke var sammenlignbare når det gjaldt viktige bakgrunnsfaktorer (f.eks. sykdommens alvorlighetsgrad og generell behandlingsmotvilje). Studiene hadde heller ikke tatt hensyn til mulige kjente forvekslingsfaktorer i analysene, og det var generelt mangelfull rapportering av data. Den ene studien hadde et retrospektivt design og beskriver ikke hvilke kriterier/verktøy som ble brukt for å måle psykosesymptomer. Den andre studien omfattet svært få deltakere som mottok antipsykotika under tvang, stor forskjell i antall deltakere i de to gruppene og personene som målte utfallene var ikke blindet.
Tilliten til effektestimatene er for lav til at vi kan konkludere hvorvidt antipsykotika gitt under tvang har en annen effekt enn antipsykotika gitt i frivillig behandling (Tabell 1).
**Diskusjon**
Basert på vårt uttømmende litteratursøk kan vi med sikkerhet si at det finnes svært lite forskning på problemstillingen, og at det som finnes er eldre studier med høy risiko for systematiske skjevheter grunnet mangelfull rapportering og mangel på justering for viktige forvekslingsfaktorer. En betydelig forskningsinnsats er derfor nødvendig for å kunne svare på problemstillingen vår. Ideelt sett skulle en slik forskningsinnsats bestå av større, veldesignete randomiserte studier. Dette er ikke mulig da det finnes store forskningsetiske, metodiske og medisinske utfordringer som er uforenelige med å forske på denne problemstillingen i denne pasientgruppen.
En alternativ måte å besvare problemstillingen er å bruke registerdata. De fleste pasienter vil i løpet av sykdomsforløpet være eksponert for forskjellige behandlingsregimer, mange vil både eksponeres for tvangsbehandling og for frivillig behandling. En måte å bruke registerdata er å sammenligne pasienters symptomer og funksjonsnivå i perioder med frivillig eller ingen behandling med perioder under tvang. Slik sammenlignes pasientene både med seg selv og med hverandre.

**Konklusjon**
Det er usikkert hvorvidt effekten av tvangsbehandling med antipsykotika er forskjellig fra effekten av frivillig behandling med antipsykotika for utfallene psykosesymptomer, reinnleggelse, og psykososial fungering.
AU  - Jardim,
AU  - Patricia
AU  - Sofia
AU  - Jacobsen
AU  - Borge,
AU  - Tiril
AU  - Cecilie
AU  - Dahm,
AU  - Kristin
AU  - Thuve
AU  - Muller,
AU  - Ashley
AU  - Elizabeth
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - Tom verdi
N1  - https://www.fhi.no/globalassets/dokumenterfiler/rapporter/2021/effekt-av-antipsykotika-ved-behandling-uten-pasientens-samtykke-sammenlignet-med-frivillig-behandling-v2-rapport-2021.pdf
PY  - 2021
TI  - Effekt av antipsykotika ved behandling uten pasientens samtykke sammenlignet med frivillig behandling: en systematisk oversikt
ER  -
TY  - JOUR
AB  - **INTRODUCTION**: Parenting interventions during early childhood are known to improve various child development outcomes immediately following programme implementation. However, less is known about whether these initial benefits are sustained over time. 

**METHODS**: We conducted a systematic literature review of parenting interventions in low- and middle-income countries (LMICs) that were delivered during the first 3 years of life and had completed a follow-up evaluation of the intervention cohort at least 1 year after the primary postintervention endpoint. We summarized intervention effects over time by child-level and parent-level outcomes as well as by timing of follow-up rounds in the short-term (1-3 years after programme completion), medium-term (4-9 years), and long-term (10+ years). We also conducted exploratory meta-analyses to compare effects on children&#039;s cognitive and behavioral development by these subgroups of follow-up rounds. 

**RESULTS**: We identified 24 articles reporting on seven randomised controlled trials of parenting interventions delivered during early childhood that had at least one follow-up study in seven LMICs. The majority of follow-up studies were in the short-term. Three trials conducted a medium-term follow-up evaluation, and only two trials conducted a long-term follow-up evaluation. Although trials consistently supported wide-ranging benefits on early child development outcomes immediately after programme completion, results revealed a general fading of effects on children&#039;s outcomes over time. Short-term effects were mixed, and medium-term and long-term effects were largely inconclusive. The exploratory meta-analysis on cognitive development found that pooled effects were significant at postintervention and in the short-term (albeit smaller in magnitude), but the effects were not significant in the medium-term and long-term. For behavioural development, the effects were consistently null over time. 

**CONCLUSIONS**: There have been few longer-term follow-up studies of early parenting interventions in LMICs. Greater investments in longitudinal intervention cohorts are needed in order to gain a more comprehensive understanding of the effectiveness of parenting interventions over the life course and to improve the design of future interventions so they can have greater potential for achieving and sustaining programme benefits over time.
AN  - 33674266
AU  - Jeong,
AU  - J.
AU  - Pitchik,
AU  - H.
AU  - O.
AU  - Fink,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1136/bmjgh-2020-004067
L1  - internal-pdf://2434706220/Jeong-2021-Short-term, medium-term and long-te.pdf
PY  - 2021
SP  - 03
T2  - BMJ Global Health
TI  - Short-term, medium-term and long-term effects of early parenting interventions in low- and middle-income countries: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med18&amp;AN=33674266
UR  - https://gh.bmj.com/content/bmjgh/6/3/e004067.full.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **Aim **To summarise the quantity and quality of evidence for using music therapy for preterm infants in the neonatal intensive care unit (NICU). 

**Methods** We performed an overview of evidence for the effectiveness and safety of MT for preterm infants in the NICU. We performed a random-effects meta-analysis of data from studies that fit the definition of MT. 

**Results** We identified 12 eligible systematic reviews and the methodological quality by AMSTAR-2 ranged from moderate to critically low. We identified 14 eligible randomised trials and 7 observational studies where the intervention fits the definition of MT. Meta-analysis of the RCTs showed that MT significantly decreases heart rate, mean difference (MD) (95% CI), -3.21 [-5.22, -1.19], respiratory rate, MD -2.93 [-5.65, -0.22], and maternal anxiety, MD -17.50 [-20.10, -14.90], and increases feeding volume, MD 29.59 [12.79, 46.38]. Long-term neurodevelopmental or safety outcomes were not reported. GRADE assessment of outcomes ranged from low to very low, downgraded for high risk of bias in the included studies, inconsistency and imprecision. 

**Conclusion** Low to very low certainty evidence suggests that MT in preterm infants improves short-term physiological parameters, feeding and maternal anxiety but safety and long-term outcomes were not reported.
AN  - WOS:000683029900001
AU  - Mohan,
AU  - A.
AU  - Gokulakrishnan,
AU  - G.
AU  - El-Saie,
AU  - A.
AU  - Brickley,
AU  - A.
AU  - Hagan,
AU  - J.
AU  - Pammi,
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/apa.16055
L1  - internal-pdf://2674015902/Mohan-Music therapy for preterm neonates in th.pdf
PY  - 2021
SP  - 21
T2  - Acta Paediatrica
TI  - Music therapy for preterm neonates in the neonatal intensive care unit: An overview of systematic reviews
UR  - &lt;Go to ISI&gt;://WOS:000683029900001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/apa.16055?download=true
ER  -
TY  - JOUR
AB  - Har ikke DOI, fulltekst finner du her: https://www.proquest.com/openview/67e43a5d45f9fb19d945b2d86dc17017/1?pq-origsite=gscholar&amp;cbl=2032023

Individuals with autism spectrum disorder (ASD) benefit from physical activity interventions. This study synthesized 14 single-case design (SCD) studies on interventions involving physical activities for individuals with ASD. The study evaluated the methodological quality of the reviewed studies by using What Works Clearinghouse (WWC) design standards and used Tau-U indices to determine the overall magnitudes of intervention effects and the potential variables that moderate improved outcomes for individuals with ASD. The results indicated that three studies met the WWC SCD design standards. Interventions involving physical activities demonstrated an overall moderate-to-large positive effect on behaviors of individuals with ASD. The effect size of sports-related skills was significantly larger than that of exercise. The smallest effect size among dependent variables was engagement and the largest was problem behavior. Interventions implemented by professional practitioners demonstrated a larger effect size than interventions implemented by teachers or teachers with researcher. Questions remain concerning what dosage of physical activity interventions would produce optimum results for individuals with ASD. Further high-quality studies are needed to examine the differences in physical activity intervention outcomes for individuals with ASD according to moderators.
AN  - WOS:000751663800008
AU  - Park,
AU  - E.
AU  - Y.
AU  - Kim,
AU  - W.
AU  - H.
AU  - Blair,
AU  - K.
AU  - S.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - Har ikke DOI
L1  - internal-pdf://0939984568/Effectiveness of Interventions Involving-2021.pdf
PY  - 2021
SP  - 354-367
T2  - Education and Training in Autism and Developmental Disabilities
TI  - Effectiveness of Interventions Involving Physical Activities for Individuals with Autism Spectrum Disorder: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000751663800008
VL  - 56
ER  -
TY  - JOUR
AB  - OBJECTIVES: To systematically describe the characteristics and techniques of prevention programmes for children of parents with mood/anxiety disorders. In addition, recruitment approaches and difficulties were identified and a meta-analysis was conducted to examine the efficacy of these prevention programmes.

METHODS: Randomized controlled trials assessing the efficacy of a prevention programme for children (6-25 years) of parents with mood and/or anxiety disorders were included. A systematic literature search was conducted in PubMed, PsychINFO, and CENTRAL from the earliest record to March 2019. In addition, programme manuals of identified prevention programmes were requested for a content analysis.

RESULTS: Twenty-two articles containing eight unique prevention programmes involving 1,325 subjects were identified. Programmes varied in the number and types of techniques, but all provided psychoeducation. Results suggested that recruitment via clinicians was more successful than recruitment via health maintenance organization databases. In a meta-analysis, a significant risk difference was found in favour of prevention programmes on the risk of developing a depressive/anxiety disorder in offspring at short-term (9-18 months follow-up; RR = 0.37, 95% CI [0.21; 0.66]) and long-term follow-up (24 months or longer follow-up; RR = 0.71, 95% CI [0.57; 0.87] and on symptom levels in offspring at post-intervention (SMD = -0.19, 95% CI [-0.36; -0.02]) and at 12-months follow-up (SMD = -0.31, 95% CI [-0.57; -0.06]).

CONCLUSIONS: The prevention programmes combined psychoeducational elements with skills training and/or cognitive-behavioural therapy elements. The recruitment process and the content of these programmes are sometimes insufficiently described. Nevertheless, they appear to be effective, indicating a need to further examine how these programmes exactly work and for whom.

PRACTITIONER POINTS: Preventive interventions for children of parents with mood/anxiety disorders appear to be effective in preventing these disorders in offspring. Available preventive intervention programmes focus mostly on psychoeducation, cognitive-behavioural therapy, and family processes. More effort should be made into describing preventive interventions so that they can be easily implemented by practitioners. Studies should further examine why and for whom preventive interventions for children of parents with mood/anxiety disorders are effective.
AD  - Havinga, Petra J. Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, University of Groningen, The Netherlands.Maciejewski, Dominique F. Department of Developmental Psychopathology, Behavioural Science Institute, Nijmegen, The Netherlands.Hartman, Catharina A. Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, University of Groningen, The Netherlands.Hillegers, Manon H J. Department of Child and Adolescent Psychology and Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands.Schoevers, Robert A. Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, University of Groningen, The Netherlands.Penninx, Brenda W J H. Department of Psychiatry and Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
AN  - 33410149
AU  - Havinga,
AU  - P.
AU  - J.
AU  - Maciejewski,
AU  - D.
AU  - F.
AU  - Hartman,
AU  - C.
AU  - A.
AU  - Hillegers,
AU  - M.
AU  - H.
AU  - J.
AU  - Schoevers,
AU  - R.
AU  - A.
AU  - Penninx,
AU  - Bwjh
DA  - Jan 06
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/bjc.12277
DP  - Ovid Technologies
J2  - Br J Clin Psychol
L1  - internal-pdf://0518822804/Havinga-2021-Prevention programmes for childre.pdf
LA  - English
N1  - Using Smart Source ParsingJanHavinga, Petra JMaciejewski, Dominique FHartman, Catharina AHillegers, Manon H JSchoevers, Robert APenninx, Brenda W J H
PY  - 2021
SP  - 06
T2  - British Journal of Clinical Psychology
TI  - Prevention programmes for children of parents with a mood/anxiety disorder: Systematic review of existing programmes and meta-analysis of their efficacy
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33410149
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33410149&amp;id=doi:10.1111%2Fbjc.12277&amp;issn=0144-6657&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=British+Journal+of+Clinical+Psychology&amp;atitle=Prevention+programmes+for+children+of+parents+with+a+mood%2Fanxiety+disorder%3A+Systematic+review+of+existing+programmes+and+meta-analysis+of+their+efficacy.&amp;aulast=Havinga&amp;pid=%3Cauthor%3EHavinga+PJ%3C%2Fauthor%3E%3CAN%3E33410149%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://bpspsychub.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bjc.12277?download=true
VL  - 06
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Neonatal abstinence syndrome (NAS) due to opioid withdrawal may result in disruption of the mother-infant relationship, sleep-wake abnormalities, feeding difficulties, weight loss, seizures and neurodevelopmental problems. OBJECTIVES: To assess the effectiveness and safety of using an opioid for treatment of NAS due to withdrawal from opioids in newborn infants. 

**SEARCH METHODS**: We ran an updated search on 17 September 2020 in CENTRAL via Cochrane Register of Studies Web and MEDLINE via Ovid. We also searched clinical trials databases, conference proceedings and the reference lists of retrieved articles for eligible trials. SELECTION CRITERIA: We included randomised controlled trials (RCTs), quasi- and cluster-RCTs which enrolled infants born to mothers with opioid dependence and who were experiencing NAS requiring treatment with an opioid. 

**DATA COLLECTION AND ANALYSIS**: Three review authors independently assessed trial eligibility and risk of bias, and independently extracted data. We used the GRADE approach to assess the certainty of evidence. 

**MAIN RESULTS**: We included 16 trials (1110 infants) with NAS secondary to maternal opioid use in pregnancy. Seven studies at low risk of bias were included in sensitivity analysis. Opioid versus no treatment / usual care: a single trial (80 infants) of morphine and supportive care versus supportive care alone reported no difference in treatment failure (risk ratio (RR) 1.29, 95% confidence interval (CI) 0.41 to 4.07; very low certainty evidence). No infant had a seizure. The trial did not report mortality, neurodevelopmental disability and adverse events. Morphine increased days hospitalisation (mean difference (MD) 15.00, 95% CI 8.86 to 21.14; very low certainty evidence) and treatment (MD 12.50, 95% CI 7.52 to 17.48; very low certainty evidence), but decreased days to regain birthweight (MD -2.80, 95% CI -5.33 to -0.27) and duration (minutes) of supportive care each day (MD -197.20, 95% CI -274.15 to -120.25). Morphine versus methadone: there was no difference in treatment failure (RR 1.59, 95% CI 0.95 to 2.67; 2 studies, 147 infants; low certainty evidence). Seizures, neonatal or infant mortality and neurodevelopmental disability were not reported. A single study reported no difference in days hospitalisation (MD 1.40, 95% CI -3.08 to 5.88; 116 infants; low certainty evidence), whereas data from two studies found an increase in days treatment (MD 2.71, 95% CI 0.22 to 5.21; 147 infants; low certainty) for infants treated with morphine. A single study reported no difference in breastfeeding, adverse events, or out of home placement. Morphine versus sublingual buprenorphine: there was no difference in treatment failure (RR 0.79, 95% CI 0.36 to 1.74; 3 studies, 113 infants; very low certainty evidence). Neonatal or infant mortality and neurodevelopmental disability were not reported. There was moderate certainty evidence of an increase in days hospitalisation (MD 11.45, 95% CI 5.89 to 17.01; 3 studies, 113 infants), and days treatment (MD 12.79, 95% CI 7.57 to 18.00; 3 studies, 112 infants) for infants treated with morphine. A single adverse event (seizure) was reported in infants exposed to buprenorphine. Morphine versus diluted tincture of opium (DTO): a single study (33 infants) reported no difference in days hospitalisation, days treatment or weight gain (low certainty evidence). Opioid versus clonidine: a single study (31 infants) reported no infant with treatment failure in either group. This study did not report seizures, neonatal or infant mortality and neurodevelopmental disability. There was low certainty evidence for no difference in days hospitalisation or days treatment. This study did not report adverse events. Opioid versus diazepam: there was a reduction in treatment failure from use of an opioid (RR 0.43, 95% CI 0.23 to 0.80; 2 studies, 86 infants; low certainty evidence). Seizures, neonatal or infant mortality and neurodevelopmental disability were not reported. A single study of 34 infants comparing methadone versus diazepam reported no difference in days hospitalisation or days treatment (very low certainty evidence). Adverse events were not reported. Opioid versus phenobarbital: there was a reduction in treatment failure from use of an opioid (RR 0.51, 95% CI 0.35 to 0.74; 6 studies, 458 infants; moderate certainty evidence). Subgroup analysis found a reduction in treatment failure in trials titrating morphine to ≧ 0.5 mg/kg/day (RR 0.21, 95% CI 0.10 to 0.45; 3 studies, 230 infants), whereas a single study using morphine &lt; 0.5 mg/kg/day reported no difference compared to use of phenobarbital (subgroup difference P = 0.05). Neonatal or infant mortality and neurodevelopmental disability were not reported. A single study (111 infants) of paregoric versus phenobarbital reported seven infants with seizures in the phenobarbital group, whereas no seizures were reported in two studies (170 infants) comparing morphine to phenobarbital. There was no difference in days hospitalisation or days treatment. A single study (96 infants) reported no adverse events in either group. Opioid versus chlorpromazine: there was a reduction in treatment failure from use of morphine versus chlorpromazine (RR 0.08, 95% CI 0.01 to 0.62; 1 study, 90 infants; moderate certainty evidence). No seizures were reported in either group. There was low certainty evidence for no difference in days treatment. This trial reported no adverse events in either group. None of the included studies reported time to control of NAS. Data for duration and severity of NAS were limited, and we were unable to use these data in quantitative synthesis. 

**AUTHORS&#039; CONCLUSIONS**: Compared to supportive care alone, the addition of an opioid may increase duration of hospitalisation and treatment, but may reduce days to regain birthweight and the duration of supportive care each day. Use of an opioid may reduce treatment failure compared to phenobarbital, diazepam or chlorpromazine. Use of an opioid may have little or no effect on duration of hospitalisation or treatment compared to use of phenobarbital, diazepam or chlorpromazine. The type of opioid used may have little or no effect on the treatment failure rate. Use of buprenorphine probably reduces duration of hospitalisation and treatment compared to morphine, but there are no data for time to control NAS with buprenorphine, and insufficient evidence to determine safety. There is insufficient evidence to determine the effectiveness and safety of clonidine.
AD  - Department of Neonatal Medicine, RPA Women and Babies, Royal Prince Alfred Hospital, Camperdown, Australia.Central Clinical School, School of Medicine, The University of Sydney, Sydney, Australia.
AN  - 34231914
AU  - Zankl,
AU  - A.
AU  - Martin,
AU  - J.
AU  - Davey,
AU  - J.
AU  - G.
AU  - Osborn,
AU  - D.
AU  - A.
DA  - Jul 7
DB  - My EndNote Library.enl
DO  - 10.1002/14651858.CD002059.pub4
DP  - NLM
J2  - The Cochrane database of systematic reviews
KW  - Buprenorphine/therapeutic use
KW  - Chlorpromazine/therapeutic use
KW  - Clonidine/therapeutic use
KW  - Diazepam/therapeutic use
KW  - Humans
KW  - Hypnotics and Sedatives/therapeutic use
KW  - Infant, Newborn
KW  - Methadone/therapeutic use
KW  - Morphine/therapeutic use
KW  - Narcotics/*therapeutic use
KW  - Neonatal Abstinence Syndrome/*drug therapy
KW  - Opioid-Related Disorders/*drug therapy
KW  - Opium/therapeutic use
KW  - Phenobarbital/therapeutic use
KW  - Randomized Controlled Trials as Topic
LA  - eng
N1  - 1469-493xZankl, AngelikaMartin, JillDavey, Jane GOsborn, David AJournal ArticleMeta-AnalysisResearch Support, Non-U.S. Gov&#039;tSystematic ReviewCochrane Database Syst Rev. 2021 Jul 7;7(7):CD002059. doi: 10.1002/14651858.CD002059.pub4.
PY  - 2021
SP  - Cd002059
T2  - Cochrane Database Syst Rev
TI  - Opioid treatment for opioid withdrawal in newborn infants
VL  - 7
ER  -
TY  - JOUR
AB  - Abstract **Background** Optimal nutrition plays a crucial role in pregnancy. Poor maternal nutrition and maternal obesity has risk factors for serious fetal complications and neonatal outcomes, including intrauterine growth restriction, congenital abnormalities, stillbirth, low birth weight (LBW), preterm birth, fetal macrosomia, increased risk of neonatal infections, neonatal hypothermia, and neonatal death. The prevalence of maternal malnutrition is higher in low- and middle-income countries (LMICs) (10&ndash;19%) when compared with high-income countries, with variation by region and by country. Several behavioral interventions, including dietary control and exercise, have been found to reduce the risk of these adverse outcomes. However, none has reviewed dietary interventions to prevent maternal obesity in pregnant women. Objectives The review aims to assess the effectiveness of balanced energy protein (BEP) supplementation, food distribution programs (FDPs), and dietary interventions to prevent maternal obesity during pregnancy on birth, child health, and developmental outcomes. 

**Search Methods** We searched Cochrane Controlled Trials Register (CENTRAL), MEDLINE, Embase, CINAHL, and 12 other databases, and trials registers for ongoing studies up until April 2019. We also searched for gray literature from different sources and for citations on Google Scholar and Web of Sciences. We also checked the reference lists of included studies and relevant reviews and contacted the authors of studies for any ongoing and unpublished studies. The search was followed by title/abstract screening, full-text screening and data extraction. Selection Criteria We included randomized control trials, and quasi experimental trials to evaluate the impact of nutritional interventions (BEP, FDP, and dietary interventions to prevent maternal obesity) compared to control or standard of care, among healthy pregnant women of any age living in LMICs. 

**Data Collection and Analysis** Two review authors independently assessed and screened studies for eligibility, extracted data, and assessed quality of the studies included in the review. We conducted a meta-analysis of all reported primary and secondary outcomes. Subgroup analysis and GRADE assessment was performed for all reported primary outcomes. 

**Main Results** The review included 15 studies, of these, eight were on BEP supplementation, five on FDP, and two on interventions for obesity prevention. BEP supplementation may show a reduction in the rate of stillbirths by 61% (risk ratio [RR], 0.39; 95% CI, 0.19&ndash;0.80; three studies, n&thinsp;=&thinsp;1913; low quality on GRADE), perinatal mortality by 50% (RR, 0.50; 95% CI, 0.30&ndash;0.84; one study, n&thinsp;=&thinsp;1446; low quality on GRADE), LBW infants by 40% (RR, 0.60; 95% CI, 0.41&ndash;0.86; three studies, n&thinsp;=&thinsp;1830; low quality of evidence on GRADE); small for gestational age (SGA) by 29% (RR, 0.71; 95% CI, 0.54&ndash;0.94; five studies, n&thinsp;=&thinsp;1844) and increased birth weight by 107.28&thinsp;g (mean difference [MD], 107.28&thinsp;g; 95% CI, 68.51&ndash;146.04, eight studies, n&thinsp;=&thinsp;2190). An increase of 107.28&thinsp;g of birthweight is clinically significant in the countries where the intervention was provided. BEP supplementation had no effect on miscarriage, neonatal mortality, infant mortality, preterm birth, birth length, and head circumference. FDP may show improvement in mean birth weight by 46&thinsp;g (MD, 46.00&thinsp;g; 95% CI, 45.10&ndash;46.90, three studies, n&thinsp;=&thinsp;5272), in birth length by 0.20&thinsp;cm (MD, 0.20&thinsp;cm; 95% CI, 0.20&ndash;0.20, three studies, n&thinsp;=&thinsp;5272), and reduction in stunting by 18% (RR, 0.82; 95% CI, 0.71&ndash;0.94; two studies; n&thinsp;=&thinsp;4166), and wasting by 13% (RR, 0.87; 95% CI, 0.78&ndash;0.97; two studies, n&thinsp;=&thinsp;3883). There was no effect of FDP on miscarriage, maternal mortality, perinatal mortality, neonatal mortality, infant mortality, preterm birth, LBW, SGA, head circumference, and underweight babies. Studies on interventions for obesity prevention among pregnant women failed to report on the primary outcomes. The studies showed a 195.57&thinsp;g reduction in mean birth weight ( D, &minus;195.57&thinsp;g, 95% CI, &minus;349.46 to &minus;41.68, two studies, n&thinsp;=&thinsp;180), and had no effect on birth length, and macrosomia. 

**Authors&#039; Conclusions** Our review highlights improvement in maternal, birth, and child outcomes through BEP supplementation and FDP during pregnancy. But, due to the small number of included studies and low quality of evidence, we are uncertain of the effect of BEP supplementation, FDP and dietary interventions for prevention of obesity on maternal, and child outcomes. Thus, further good quality research is recommended to assess the effect of these interventions on maternal, child and developmental outcomes.
AU  - Lassi,
AU  - Zohra
AU  - S.
AU  - Padhani,
AU  - Zahra
AU  - A.
AU  - Rabbani,
AU  - Amna
AU  - Rind,
AU  - Fahad
AU  - Salam,
AU  - Rehana
AU  - A.
AU  - Bhutta,
AU  - Zulfiqar
AU  - A.
DB  - My EndNote Library.enl
DO  - /10.1002/cl2.1150
PY  - 2021
SP  - e1150
T2  - Campbell Systematic Reviews
TI  - Effects of nutritional interventions during pregnancy on birth, child health and development outcomes: A systematic review of evidence from low- and middle-income countries
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/cl2.1150
VL  - 17
ER  -
TY  - JOUR
AB  - The purpose of this study was to evaluate the effectiveness of existing psychological interventions on the social adjustment of young refugees. 

From 51 peer-reviewed articles identified in the literature, 11 studies with 25 therapeutic effect sizes met criteria for inclusion (N= 1,736). Hedges&#039; g was used to measure effect sizes and a random-effects model was conducted. The number of sessions and participant age were considered as potential moderator variables in moderator analyses through meta-regression. The effect sizes of the included studies were compared based on the type of intervention. 

The results showed that the aggregated effect size for all included interventions was significant, computed as g = 0.14, p&lt;0.01, 95% confidence interval [0.06, 0.21]. The effect size is considered small, based on Cohen&#039;s (1992) guidelines. The results of the meta-regression showed that the effectiveness of the included psychological interventions on social adjustment was not moderated by either the number of sessions (b = 0.006 p= 0.35) or age (b= -0.008, p= 0.59). Furthermore, there were no significant differences between different therapeutic approaches (Q = 7.37, df (Q) = 6; p = 0.28). This meta-analysis demonstrates that mental-health interventions in young refugees mildly improve their social adjustment. Due to the importance of social adjustment in refugees, we suggest that existing interventions place greater specific focus on improving social adjustment. The details of implications for future studies are discussed.
AN  - WOS:000705272700048
AU  - Forooshani,
AU  - S.
AU  - A.
AU  - Izadikhah,
AU  - Z.
AU  - Renzaho,
AU  - A.
AU  - M.
AU  - N.
AU  - O&#039;Connor,
AU  - P.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/jrs/fez035
L1  - internal-pdf://3861977919/Forooshani-2021-Effectiveness of Psychological.pdf
PY  - 2021
SP  - 976-992
T2  - Journal of Refugee Studies
TI  - Effectiveness of Psychological Interventions on Young Refugees&#039; Social Adjustment: A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000705272700048
UR  - https://watermark.silverchair.com/fez035.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtAwggLMBgkqhkiG9w0BBwagggK9MIICuQIBADCCArIGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMWoj4JC6xq1pP4fc0AgEQgIICg3C2fkF-idxRGIbkg71xCJEPQ-OG_TqdzLSRQwnVN9qdJ1Txhis1kuUq1ckI3TnIunZLu5unaLMl0pHQQVwf0qvMWkcJh6FQL_o3TSN68-xDdlNs-mM0JEA6XkKeGWt1wmVCEyywWKBKR0F1PN83tY1anOoyoO3pI5BMTKrYrygu20RsxAVCNeu7XFxGhvYLZFLamS35f8xdPU7hD8BMKxdGTORUNbj0vc-o_seEF6IPPNBRYqTCmnekTirdGn7i-7zQriGIp2EuAKjaaFHM1X-uyaIDPLkt_oGOFZbGy-MNpbT3nYLZ5FXD1gUZeuOlr26zeNvgStdQH-u3Vu87qrH9FrJhTcwbLp6JBJi3LdQsPCFsjheCfWMzwhQo1egz4ssV6rGv2H9yCpYNBxpdaGW2MbUIs-EtSi5d9YYf5ZCykBoRUZIHdTuaALHFcNjI8CWLpKBOILmnnK63X4pnVhTWAZ8SRnLngDg36_d4hTCLqgH2tP3ERyNbm8tfy5xSOFkedEwI6My5kK9mQWt_8_BSOAv4QpMZxQSnBZH_suMTvXhCpNBU57fXHAfZRu7iAj6DhBekVrrpcdk-nuUfOgZJ9P1lQ6hneSRCjCEPGzC7HYJ6yS1xilM-vdPaK47N-SWufhk3zpUM1_uxtOhc90rPlE3kPra2Rtq5yzlWQ-ky9PTNQPMj-QBFkZYMgjHHG9jItpnHX0zzOahXmJd7sc7AazjcCfNGRvFX_0VWmQRpR5DM_IsuVH98YP7D05L1PJwqrrbgKW_wJ2Kw_68rjE0y4shWa_RBSLmcjd3oQcq3Wgba45568LkDb7bhNzMb6j0TDKi--_oXbXFPnc0spjx5wJ8
VL  - 34
ER  -
TY  - JOUR
AB  - **BACKGROUND**: The present meta-analysis aimed to evaluate the efficacy of various non-pharmacological interventions on comorbid emotional symptoms such as depression, anxiety, and emotional dysregulation (ED) in children and adults with ADHD.

**METHOD**: Forty-four randomized controlled trials (23 studies with ADHD children and 21 studies with ADHD adults) were included. Risk of bias, heterogeneity assessment, and subgroup analyses were conducted.

**RESULTS**: We found that therapies targeting the relationship between children and others (i.e., parent-training [on ED and depression] and social skills training [on ED]) were efficacious in the treatment of emotional symptoms in children with ADHD at post-intervention. As for adults with ADHD, cognitive behavioral therapy was found to be effective for the improvement of emotional symptoms at both post-intervention and follow-up.

**CONCLUSION**: Our findings demonstrate that the efficacy of non-pharmacological interventions varies substantially across children and adults with ADHD. These results provide important implications for the selection of non-pharmacological interventions for children with ADHD.
AD  - Guo, Chao. The Affiliated Hospital of Hangzhou Normal University, Hangzhou, P.R. China.Guo, Chao. Institute of Psychological Science, Hangzhou Normal University, P.R. China.Guo, Chao. Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, P.R. China.Assumpcao, Leonardo. The Affiliated Hospital of Hangzhou Normal University, Hangzhou, P.R. China.Assumpcao, Leonardo. Institute of Psychological Science, Hangzhou Normal University, P.R. China.Assumpcao, Leonardo. Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, P.R. China.Hu, Zhiguo. The Affiliated Hospital of Hangzhou Normal University, Hangzhou, P.R. China.Hu, Zhiguo. Institute of Psychological Science, Hangzhou Normal University, P.R. China.Hu, Zhiguo. Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, P.R. China.
AN  - 33759605
AU  - Guo,
AU  - C.
AU  - Assumpcao,
AU  - L.
AU  - Hu,
AU  - Z.
DA  - Mar 24
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/10870547211001953
DP  - Ovid Technologies
J2  - J Atten Disord
L1  - internal-pdf://2788955601/Guo-2021.pdf
LA  - English
N1  - Guo, ChaoAssumpcao, LeonardoHu, Zhiguo
PY  - 2021
SP  - 10870547211001953
T2  - Journal of Attention Disorders
TI  - Efficacy of Non-pharmacological Treatments on Emotional Symptoms of Children and Adults with Attention-Deficit/Hyperactivity Disorder: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33759605
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33759605&amp;id=doi:10.1177%2F10870547211001953&amp;issn=1087-0547&amp;isbn=&amp;volume=&amp;issue=&amp;spage=10870547211001953&amp;pages=10870547211001953&amp;date=2021&amp;title=Journal+of+Attention+Disorders&amp;atitle=Efficacy+of+Non-pharmacological+Treatments+on+Emotional+Symptoms+of+Children+and+Adults+with+Attention-Deficit%2FHyperactivity+Disorder%3A+A+Meta-Analysis.&amp;aulast=Guo&amp;pid=%3Cauthor%3EGuo+C%3C%2Fauthor%3E%3CAN%3E33759605%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/10.1177/10870547211001953
UR  - https://journals.sagepub.com/doi/pdf/10.1177/10870547211001953
ER  -
TY  - JOUR
AB  - BAKGRUNN
Circle of Security (COS), eller Trygghetssirkelen på norsk, er en gruppe intervensjoner utviklet for å fremme god tilknytning mellom foreldre og barn. Intervensjonene retter seg primært mot foreldrenes evne til å forstå barnets grunnleggende behov for trygghet, tilhørighet og autonomi slik at barnets trygghetsfølelse og selvforståelse øker.

Denne kunnskapsoppsummeringen beskriver Circle of Security &ndash; International Parenting (COS-P), som er en forebyggende gruppeintervensjon rettet mot foreldre. Tiltaket er utviklet for å tilbys familier uten kjent risiko for utvikling av tilknytningsproblematikk. I Norge driftes tiltaket av Tilknytningspsykologene i samarbeid med Circle of Security International i USA.

METODE
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS, CINAHL og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

RESULTATER
Resultatene består av en vurdering av tiltakets beskrivelse, foreliggende studier og implementeringskvalitet. COS-VG vurderes som et godt beskrevet tiltak med en god teoretisk forankring. Det finnes en nordisk effektstudie av tiltaket, hvor det ikke ble funnet noen signifikant forskjell i effekt mellom en gruppe som mottok COS-P i tillegg til vanlig behandling (TAU) og en annen gruppe som mottok kun TAU. Det er dermed usikker hvilken virkning tiltaket faktisk har med tanke på å kunne fremme trygg tilknytning.

KONKLUSJON
COS-P klassifiseres på evidensnivå 2 &ndash; Teoretisk begrunnet tiltak.
AU  - Rye,
AU  - M.,
AU  - Eng,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2021
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsumering og klassifisering av tiltaket: Circle of Security (COS) International &ndash; Parenting (COS-P) (2.utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/circle-of-security-cos-international-parenting-cos-p-2-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - **INTRODUCTION**: In the last decades, different studies have investigated the effects of exercise or physical activity (PA) on cognitive functions and academic performance in children and adolescents. But given the inconsistencies regarding methodologies and the fact that many studies do not have controlled or randomized designs, a more recent review is needed in order to summarize the different outcomes and methodologies employed and correlate them from an applied perspective.

**OBJECTIVES**: The purpose of the present review is to systematically review and analyze the effects of acute and chronic PA interventions exclusively from randomized controlled trials (RCTs) on cognitive functions and academic performance of children and adolescents.

**METHODS**: A literature search was conducted using MEDLINE (via PubMed), EMBASE, Web of Science, and PsycINFO databases for all RCTs published between January 2014 and July 2020. Authors searched these databases using controlled vocabularies, keywords, and Boolean logic, and data were later extracted from the studies. Effect sizes were calculated based on means and SDs at posttest using Hedge&#039;s g formula.

**RESULTS**: A total of 20 studies met the inclusion criteria. They were assessed for eligibility and later included in the review. Although most of the articles did not show any robust effect size and had significant methodological differences, 80% of the studies analyzed showed positive results, indicating a significant impact of exercise or PA on cognition.DISCUSSION: Due to the heterogeneity in the design of the interventions and the variables analyzed, most of the studies showed small or medium effect sizes. Studies with big effect size in all variables had in common the fact that they involved team game variations and coordination activities. The combination of physical exertion (high intensity) and cognitive engagement with social interactions seems to have the strongest effect on executive functions. This ecological and attractive model reflects children&#039;s typical PA and might represent an ideal model for exercise in this population.

**CONCLUSIONS**: Although grouping different studies based on PA type, control groups, and comparison treatments is a limitation and results should be interpreted with caution, this review suggests that PA interventions, in particular, team game variations and coordination activities, have positive effects on children&#039;s cognitive functions.
AD  - Ferreira Vorkapic, Camila. Laboratory of Biosciences of Human Kinetics - LABIMH, Department of Medicine, Tiradentes University (Unit), Aracaju, Brazil.Alves, Heloisa. Department of Psychology, University of Massachusetts, Dartmouth, Massachusetts, USA.Araujo, Larissa. Laboratory of Biosciences of Human Kinetics - LABIMH, Department of Medicine, Tiradentes University (Unit), Aracaju, Brazil.Joaquim Borba-Pinheiro, Claudio. Campus Tucurui, State University of Para (UEPA), Tucurui, Brazil.Joaquim Borba-Pinheiro, Claudio. Campus Tucurui, Federal Institute of Para (IFPA), Tucurui, Brazil.Coelho, Renato. Laboratory of Biosciences of Human Kinetics - LABIMH, Department of Medicine, Tiradentes University (Unit), Aracaju, Brazil.Coelho, Renato. Multidisciplinary Residence Program, Health Secretariat of the City of Contagem, Contagem, Brazil.Fonseca, Eugenio. Laboratory of Biosciences of Human Kinetics - LABIMH, Department of Medicine, Tiradentes University (Unit), Aracaju, Brazil.Oliveira, Ana. Laboratory of Biosciences of Human Kinetics - LABIMH, Department of Medicine, Tiradentes University (Unit), Aracaju, Brazil.Dantas, Estelio H M. Laboratory of Biosciences of Human Kinetics - LABIMH, Department of Medicine, Tiradentes University (Unit), Aracaju, Brazil.Dantas, Estelio H M. Postgraduate Program in Health and Environment, Laboratory of Biosciences of Human Kinetics - LABIMH, Aracaju, Brazil.
AN  - 33887743
AU  - Ferreira
AU  - Vorkapic,
AU  - C.
AU  - Alves,
AU  - H.
AU  - Araujo,
AU  - L.
AU  - Joaquim
AU  - Borba-Pinheiro,
AU  - C.
AU  - Coelho,
AU  - R.
AU  - Fonseca,
AU  - E.
AU  - Oliveira,
AU  - A.
AU  - Dantas,
AU  - E.
AU  - H.
AU  - M.
DA  - Apr 22
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1159/000514682
DP  - Ovid Technologies
J2  - Neuropsychobiology
L1  - internal-pdf://2389857151/Ferreira Vorkapic-2021.pdf
LA  - English
M3  - Systematic Review
N1  - Ferreira Vorkapic, CamilaAlves, HeloisaAraujo, LarissaJoaquim Borba-Pinheiro, ClaudioCoelho, RenatoFonseca, EugenioOliveira, AnaDantas, Estelio H M
PY  - 2021
SP  - 1-29
T2  - Neuropsychobiology
TI  - Does Physical Activity Improve Cognition and Academic Performance in Children? A Systematic Review of Randomized Controlled Trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33887743
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33887743&amp;id=doi:10.1159%2F000514682&amp;issn=0302-282X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-29&amp;date=2021&amp;title=Neuropsychobiology&amp;atitle=Does+Physical+Activity+Improve+Cognition+and+Academic+Performance+in+Children%3F+A+Systematic+Review+of+Randomized+Controlled+Trials.&amp;aulast=Ferreira+Vorkapic&amp;pid=%3Cauthor%3EFerreira+Vorkapic+C%3C%2Fauthor%3E%3CAN%3E33887743%3C%2FAN%3E%3CDT%3ESystematic+Review%3C%2FDT%3E
UR  - https://www.karger.com/Article/Pdf/514682
ER  -
TY  - JOUR
AB  - There has been increasing interest in parent-mediated interventions (PMIs) for children with autism spectrum disorders (ASDs). 

The objective of this systematic review and meta-analysis was to examine the effect of PMIs compared to no PMI for children with ASD aged 2-17 years. The primary outcome was adaptive functioning rated by a parent or clinician. The secondary outcomes were long-term adaptive functioning rated by the parents, adverse events, core symptoms of ASD, disruptive behavior, parental well-being, quality of life of the child rated by the parents and anxiety.

 The MEDLINE, PsycInfo, Embase, and CINAHL databases were searched in March 2020. The Cochrane Risk of Bias Tool was used to rate the individual studies, and the certainty in the evidence was evaluated using GRADE. 

We identified 30 relevant randomized controlled trials (RCTs), including 1,934 participants. A clinically relevant effect of PMIs on parent-rated adaptive functioning was found with a low certainty of evidence [Standard mean difference (SMD): 0.28 (95% CI: -0.01, 0.57)] on Vineland Adaptive Behavior Scales (VABS), whereas no clinically relevant effect was seen for clinician-rated functional level, with a very low certainty of evidence [SMD on Clinical Global Impressions (CGI)-severity scale: SMD -0.45 [95% CI: -0.87, -0.03)]. PMIs may slightly improve clinician-rated autism core symptoms [SMD: -0.35 (95% CI: -0.71, 0.02)]. Additionally, no effect of PMIs on parent-rated core symptoms of ASD, parental well-being or adverse effects was identified, all with a low certainty of evidence. There was a moderate certainty of evidence for a clinically relevant effect on disruptive behavior [SMD: 0.55 (95% Cl: 0.36, 0.74)]. The certainty in the evidence was downgraded due to serious risk of bias, lack of blinding, and serious risk of imprecision due to few participants included in meta-analyses. 

The present findings suggest that clinicians may consider introducing PMIs to children with ASD, but more high-quality RCTs are needed because the effects are not well-established, and the results are likely to change with future studies. The protocol for the systematic review is registered at the Danish Health Authority website (www.sst.dk).
AN  - 34867556
AU  - Conrad,
AU  - C.
AU  - E.
AU  - Rimestad,
AU  - M.
AU  - L.
AU  - Rohde,
AU  - J.
AU  - F.
AU  - Petersen,
AU  - B.
AU  - H.
AU  - Korfitsen,
AU  - C.
AU  - B.
AU  - Tarp,
AU  - S.
AU  - Cantio,
AU  - C.
AU  - Lauritsen,
AU  - M.
AU  - B.
AU  - Handel,
AU  - M.
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2021.773604
L1  - internal-pdf://1854083982/fpsyt-12-773604.cleaned.pdf
PY  - 2021
SP  - 773604
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Parent-Mediated Interventions for Children and Adolescents With Autism Spectrum Disorders: A Systematic Review and Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34867556
VL  - 12
ER  -
TY  - JOUR
AB  - **BACKGROUND**: The presence of parents during the dental appointment can affect the child&#039;s behaviour and, consequently, the success of the treatment.AIM: This systematic review aimed to evaluate whether parents&#039; presence in the operatory room influences children&#039;s behaviour, anxiety and fear during dental treatment.

**DESIGN**: EMBASE, Cochrane Library, LILACS, PubMed, PsycINFO, Scopus, Web of Science, Google Scholar, OpenGrey and ProQuest Dissertations and Theses Databases were searched. Randomized and non-randomized clinical trials in which some measure assessing children&#039;s behaviour and/or anxiety and fear during dental treatment with the presence and absence of parents were included. Two reviewers assessed studies for selection, extracted data, evaluated bias (Joanna Briggs Institute) and graded the certainty of evidence (Grading of Recommendations, Assessment, Development and Evaluation). Random-effects meta-analyses using mean difference (MD) and narrative synthesis were performed.

**RESULTS**: A total of 2846 papers were identified, and after a 2-phase selection, sixteen studies were included (five in meta-analyses). There was no difference in children&#039;s behaviour in the presence or absence of parents (P = .23, P = .40, P = .60 and P = .89, respectively). The presence or absence of parents did not influence children&#039;s anxiety (P = .94 and P = .97) or fear (DM: -0.08; CI:-0.34-0.19, P = .24). All included studies presented a high risk of bias, and the certainty of evidence was considered to be very low.

**CONCLUSION**: It is concluded that parents&#039; presence in the operation room does not influence children&#039;s (up to 12 years old) behaviour, anxiety and fear during dental treatment with very low certainty of evidence. Methodological limitations of included studies, however, suggest that better designed trials are needed to adequately understand this issue.
AD  - Passos De Luca, Mariana. Centro Universitario Newton Paiva, Belo Horizonte, Minas Gerais, Brazil.Massignan, Carla. Faculdade de Ciencias da Saude, Brasilia, Distrito Federal, Brazil.Bolan, Michele. Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil.Butini Oliveira, Luciana. Faculdade Sao Leopoldo Mandic, Campinas, Sao Paulo, Brazil.Aydinoz, Secil. University of Missouri, Columbia, MO, USA.Dick, Bruce. Department of Anesthesiology and Pain Medicine, University of Alberta, Edmonton, AB, Canada.De Luca Canto, Graziela. Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil.
AN  - 33258144
AU  - Passos
AU  - De
AU  - Luca,
AU  - M.
AU  - Massignan,
AU  - C.
AU  - Bolan,
AU  - M.
AU  - Butini
AU  - Oliveira,
AU  - L.
AU  - Aydinoz,
AU  - S.
AU  - Dick,
AU  - B.
AU  - De
AU  - Luca
AU  - Canto,
AU  - G.
DA  - May
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/ipd.12762
DP  - Ovid Technologies
J2  - Int J Paediatr Dent
KW  - *Anxiety
KW  - Child
KW  - Dental Anxiety
KW  - Fear
KW  - Humans
KW  - *Parents
L1  - internal-pdf://1905406922/Passos De Luca-2021.pdf
LA  - English
M3  - Review
Systematic Review
N1  - Passos De Luca, MarianaMassignan, CarlaBolan, MicheleButini Oliveira, LucianaAydinoz, SecilDick, BruceDe Luca Canto, Graziela
PY  - 2021
SP  - 318-336
T2  - International Journal of Paediatric Dentistry
TI  - Does the presence of parents in the dental operatory room influence children&#039;s behaviour, anxiety and fear during their dental treatment? A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=33258144
UR  - https://onlinelibrary.wiley.com/doi/10.1111/ipd.12762
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ipd.12762?download=true
VL  - 31
ER  -
TY  - JOUR
AB  - Sammanfattning
**Syfte och bakgrund**
I den h&auml;r rapporten utv&auml;rderas internetf&ouml;rmedlad psykologisk behandling, definierat som en insats d&auml;r patienten, efter sedvanlig professionell diagnostik, på
egen hand går igenom stegen i behandlingen som erbjuds via internet. St&ouml;det från behandlaren &auml;r i dessa behandlingar begr&auml;nsat till korta, ofta skriftliga, kontakter på distans.
SBU:s tidigare rapport (SBU. Internetf&ouml;rmedlad psykologisk behandling vid ångest- och f&ouml;rst&auml;mningssyndrom 2013) visade att internetf&ouml;rmedlad kognitiv
beteendeterapi (iKBT) med st&ouml;d av behandlare på n&auml;tet, j&auml;mf&ouml;rt med v&auml;ntelista (ingen behandling), kan hj&auml;lpa vuxna som har ångest och depression och
som sj&auml;lva har valt metoden. D&auml;remot fanns det inte tillr&auml;ckligt vetenskapligt underlag f&ouml;r att j&auml;mf&ouml;ra effekten med andra relevanta behandlingsalternativ,
exempelvis behandling d&auml;r patienten tr&auml;ffar en terapeut, individuellt eller i grupp. SBU:s syfte med den aktuella uppdateringen, inom regeringsuppdraget psykisk oh&auml;lsa (dnr S2019/05315/RS), &auml;r att j&auml;mf&ouml;ra internetf&ouml;rmedlad psykologisk behandling med andra alternativ som f&ouml;rekommer inom
vården idag genom att utv&auml;rdera behandlingarnas positiva och negativa effekter och kostnadseffektivitet samt belysa etiska aspekter. Behandlingsalternativen
innefattar till exempel olika psykologiska behandlingar och l&auml;kemedel. Resultaten avser personer som vid professionell diagnostik har bed&ouml;mts uppfylla kriterier f&ouml;r depressivt syndrom, ångestsyndrom, tvångssyndrom eller trauma- och stressrelaterat syndrom, enligt olika versioner av International Statistical
Classification of Diseases and Related Health Problems (ICD) eller Diagnostic and Statistical Manual of Mental Disorders (DSM).
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2021
TI  - Internetf&ouml;rmedlad psykologisk behandling: J&auml;mf&ouml;relse med andra behandlingar vid psykiatriska syndrom
UR  - https://www.sbu.se/sv/publikationer/SBU-utvarderar/internetformedlad-psykologisk-behandling--jamforelse-med-andra-behandlingar-vid-psykiatriska-syndrom/
ER  -
TY  - JOUR
AB  - We examined the quality of evidence supporting the effects of Naturalistic Developmental Behavioral Interventions (NBDIs) for facilitating change in young children with autism. We also investigated whether effects varied as a function of specific features of the intervention, samples, and outcomes measured. Twenty-seven studies testing the effects of NDBIs were extracted from data collected for the Autism Intervention Meta-analysis (Project AIM), a comprehensive meta-analysis of group design, nonpharmacological intervention studies for children with autism aged 0-8 years. We extracted effect sizes for 454 outcomes from these studies for use in meta-regression analyses testing associations between intervention effects and mean participant chronological age, language age, autism symptomatology, percentage of sample reported as male, cumulative intervention intensity, interventionist, outcome boundedness, outcome proximity, and risk of parent/teacher training correlated measurement error. The extant literature on NDBIs documents effects on social communication, language, play, and cognitive outcomes. However, our confidence in the positive and significant summary effects for these domains is somewhat limited by methodological concerns. Intervention effects were larger for context-bound outcomes (relative to generalized), and for proximal outcomes (relative to distal). Our results indicate that NDBIs have promise as an approach for supporting development for some, but not all of the core and related features of autism in early childhood. Confidence in summary effect estimates is limited by study quality concerns, particularly an overreliance on measures subject to high detection bias. The results of this review support the use of proximity and boundedness as indicators of the limits of intervention effects. LAY SUMMARY: Naturalistic Developmental Behavioral Interventions may increase language, social communication, play skills, and cognition in young children with autism, but these increases are largest for skills directly targeted by the intervention, and in contexts that are similar to that of the intervention. These conclusions are tempered by some concerns regarding research design across the studies that have been conducted to date.
AD  - Crank, Jenna E. Special Education Department, The University of Texas at Austin, Austin, Texas, USA.Sandbank, Micheal. Special Education Department, The University of Texas at Austin, Austin, Texas, USA.Dunham, Kacie. Neuroscience Graduate Program, Vanderbilt University, Nashville, Tennessee, USA.Crowley, Shannon. Lynch School of Education and Human Development, Boston College, Chestnut Hill, Massachusetts, USA.Bottema-Beutel, Kristen. Lynch School of Education and Human Development, Boston College, Chestnut Hill, Massachusetts, USA.Feldman, Jacob. Department of Hearing and Speech Sciences, Vanderbilt University, Nashville, Tennessee, USA.Woynaroski, Tiffany G. Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Vanderbilt Brain Institute, Vanderbilt Kennedy Center, Frist Center for Autism and Innovation, Nashville, Tennessee, USA.
AN  - 33480474
AU  - Crank,
AU  - J.
AU  - E.
AU  - Sandbank,
AU  - M.
AU  - Dunham,
AU  - K.
AU  - Crowley,
AU  - S.
AU  - Bottema-Beutel,
AU  - K.
AU  - Feldman,
AU  - J.
AU  - Woynaroski,
AU  - T.
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/aur.2471
DP  - Ovid Technologies
J2  - Autism Res
L1  - internal-pdf://3367601547/Crank-2021.pdf
LA  - English
N1  - Using Smart Source ParsingJanCrank, Jenna ESandbank, MichealDunham, KacieCrowley, ShannonBottema-Beutel, KristenFeldman, JacobWoynaroski, Tiffany G
PY  - 2021
SP  - 22
T2  - Autism research : Official Journal of the International Society for Autism Research
TI  - Understanding the Effects of Naturalistic Developmental Behavioral Interventions: A Project AIM Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33480474
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33480474&amp;id=doi:10.1002%2Faur.2471&amp;issn=1939-3806&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Autism+research+%3A+Official+Journal+of+the+International+Society+for+Autism+Research&amp;atitle=Understanding+the+Effects+of+Naturalistic+Developmental+Behavioral+Interventions%3A+A+Project+AIM+Meta-analysis.&amp;aulast=Crank&amp;pid=%3Cauthor%3ECrank+JE%3C%2Fauthor%3E%3CAN%3E33480474%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/10.1002/aur.2471
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aur.2471?download=true
VL  - 22
ER  -
TY  - JOUR
AB  - BACKGROUND: Children undergoing surgery generally experience anxiety during the perioperative period, which could impact the surgical outcome, cause long-term psychological consequences and result in later healthcare avoidance. Preoperative anxiety in children is managed using both pharmacological and non-pharmacological therapies. The latter include distraction, a tour of the operating room and parental presence until the induction of anaesthesia. A novel and effective non-pharmacological therapies is the use of virtual reality to reduce anxiety and pain in children scheduled for medical procedures. However, the effectiveness of virtual reality in paediatric surgery has yet to be evaluated in a systematic review. 

OBJECTIVE: To evaluate the effectiveness of virtual reality in the management of anxiety in paediatric patients during the perioperative period. DESIGN: Both a systematic review and a meta-analysis of randomised controlled trials were performed according to the methods outlined in the Cochrane Handbook for Systematic Reviews of Interventions Section 8.5 and in accordance with the Cochrane Effective Practice and Organisation of Care. The results are reported as prescribed by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. DATA SOURCES: A systematic search of randomised controlled trials was conducted using Medline, SCOPUS, Web of Science, Ovid MEDLINE and CINAHL. 

REVIEW METHODS: Two researchers screened potentially eligible articles and then assessed the quality of the reported studies using the criteria outlined in the Cochrane Handbook for Systematic Reviews of Interventions Section 8.5 and according to Cochrane Effective Practice and Organisation of Care. The data were synthesised using the random-effects models to incorporate the estimated heterogeneity in the weighting. Heterogeneity was tested using the Q and I&lt;sup&gt;2&lt;/sup&gt; statistics. The tau&lt;sup&gt;2&lt;/sup&gt; statistic, an estimate of the amount of variation between the included studies, was also determined. Studies whose heterogeneity with respect to primary outcome measurements hindered pooling of the results for meta-analysis were summarised narratively. 

RESULTS: Seven studies were eligible for inclusion in this systematic review. An effect size for anxiety could be determined in six. The results support the effectiveness of virtual reality in reducing anxiety in paediatric patients undergoing elective surgery. The overall effect was supported by a confidence interval &lt; 0 (PL = -0.341, 95% confidence interval: -0.620 to -0.107) and by heterogenity indexes that were non significant (Q = 9.49, p = 0.091) or not important (I&lt;sup&gt;2&lt;/sup&gt; = 38.64%). 

CONCLUSIONS: Paediatric patients undergoing elective surgery may benefit from virtual reality as a distraction method that can reduce anxiety. PROSPERO register, number: (blinded for Referee).
AN  - 34781118
AU  - Simonetti,
AU  - V.
AU  - Tomietto,
AU  - M.
AU  - Comparcini,
AU  - D.
AU  - Vankova,
AU  - N.
AU  - Marcelli,
AU  - S.
AU  - Cicolini,
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ijnurstu.2021.104115
L1  - internal-pdf://1605615209/Simonetti-2021.pdf
PY  - 2021
SP  - 104115
T2  - International Journal of Nursing Studies
TI  - Effectiveness of virtual reality in the management of paediatric anxiety during the peri-operative period: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34781118
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0020748921002625?via%3Dihub
VL  - 125
ER  -
TY  - JOUR
AB  - **BACKGROUND**: In this manuscript, we summarize the findings of a systematic review that informed the development of the World Health Organization&#039;s recommendations related to psychosocial interventions for child and adolescent sexual abuse.

**METHOD**: Systematic searches across 14 databases were conducted to retrieve any published randomized controlled trials of psychosocial interventions addressing mental health outcomes among children and adolescents exposed to sexual abuse who have experienced symptoms. We assessed study risk of bias using the Cochrane Risk of Bias tool and certainty of the evidence using GRADE (Grading of Recommendations Assessment, Development and Evaluation) criteria.

**RESULTS**: Twenty-four articles representing fifteen studies were included in the systematic review. Only two studies were conducted in low- or middle-income countries. Few studies could be pooled together because of differences in interventions and comparators. Due to the small numbers of participants and very serious concerns with risk of bias, we are very uncertain about the benefits of interventions provided to children alone and without the involvement of their caregivers. However, cognitive behavior therapy (CBT) with a trauma focus provided to children and involving their caregivers may reduce some mental health symptoms associated with sexual abuse experiences.

**DISCUSSION**: The findings suggest that more and larger studies are needed to evaluate the effects of psychosocial interventions for children and adolescents exposed to sexual abuse who preside in low- and middle-income countries. PROSPERO registration number: CRD42016039656.
AD  - McTavish, Jill R. Department of Psychiatry &amp; Behavioural Neurosciences, McMaster University, Canada. Electronic address: mctavisj@mcmaster.ca.Santesso, Nancy. Department of Health Research Methods, Evidence and Impact, McMaster University, Canada.Amin, Avni. Department of Reproductive Health &amp; Research, World Health Organization, Switzerland.Reijnders, Megin. Department of Reproductive Health &amp; Research, World Health Organization, Switzerland.Ali, Muhammad Usman. McMaster Evidence Review and Synthesis Team, McMaster University, Canada.Fitzpatrick-Lewis, Donna. McMaster Evidence Review and Synthesis Team, McMaster University, Canada.MacMillan, Harriet L. Department of Psychiatry &amp; Behavioural Neurosciences, McMaster University, Canada; Department of Pediatrics, McMaster University, Canada.
AN  - 31677720
AU  - McTavish,
AU  - J.
AU  - R.
AU  - Santesso,
AU  - N.
AU  - Amin,
AU  - A.
AU  - Reijnders,
AU  - M.
AU  - Ali,
AU  - M.
AU  - U.
AU  - Fitzpatrick-Lewis,
AU  - D.
AU  - MacMillan,
AU  - H.
AU  - L.
DA  - Jun
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.chiabu.2019.104203
DP  - Ovid Technologies
J2  - Child Abuse Negl
L1  - internal-pdf://1022518906/1-s2.0-S0145213419303801-main.cleaned.pdf
LA  - English
N1  - McTavish, Jill RSantesso, NancyAmin, AvniReijnders, MeginAli, Muhammad UsmanFitzpatrick-Lewis, DonnaMacMillan, Harriet LS0145-2134(19)30380-1
PY  - 2021
SP  - 104203
T2  - Child Abuse &amp; Neglect
TI  - Psychosocial interventions for responding to child sexual abuse: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31677720
VL  - 116
ER  -
TY  - JOUR
AB  - Cyberbullying among youth is an emerging public health concern that has a wide array of deleterious outcomes. The current meta-analytic review synthesized school-based cyberbullying prevention programs&#039; impact on promoting cyber-bystander intervention among K-12 students. As a result of exhaustive searches and a thorough screening procedure, a total of 9 studies were identified as eligible. Meta-analytic synthesis of the 9 studies involving 35 effect sizes demonstrated that overall, the treatment effect was not statistically significant (g = 0.29, SE = 0.14, p = .07, 95% CI [-0.03, 0.61]). Findings of the moderator analyses suggest that incorporating an empathy activation component in the prevention program was associated with better program effectiveness in promoting cyber-bystander intervention. Further, older age was found to be associated with better program outcomes. Findings of the current meta-analysis provide important insight for developing cyberbullying prevention programs that promote cyber-bystander intervention. Supplemental data for this article is available online at http://dx.doi.org/
AN  - WOS:000682451500001
AU  - Torgal,
AU  - C.
AU  - Espelage,
AU  - D.
AU  - L.
AU  - Polanin,
AU  - J.
AU  - R.
AU  - Ingram,
AU  - K.
AU  - M.
AU  - Robinson,
AU  - L.
AU  - E.
AU  - El
AU  - Sheikh,
AU  - A.
AU  - J.
AU  - Valido,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/2372966x.2021.1913037
L1  - internal-pdf://1018908660/Torgal-A Meta-Analysis of School-Based Cyberbu.pdf
PY  - 2021
SP  - 15
T2  - School Psychology Review
TI  - A Meta-Analysis of School-Based Cyberbullying Prevention Programs&#039; Impact on Cyber-Bystander Behavior
UR  - &lt;Go to ISI&gt;://WOS:000682451500001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/2372966X.2021.1913037?needAccess=true
ER  -
TY  - JOUR
AB  - The goal of this study was to examine the effects of behavioral sleep extension interventions on sleep duration outcomes in children and adults &gt;= age 12. We conducted a systematic literature review, article extraction and meta-analysis. 

Our search yielded 42 studies from 14 countries. The majority of studies (n = 19) enrolled adults, 10 studies enrolled college students, 13 enrolled children (high school or middle school aged). 

Results from the meta-analysis demonstrated behavioral sleep extension resulted in a significantly higher sleep duration as compared to control group or baseline, with pooled standardized mean difference (SMD) that was similar for both two-arm 0.80 (95 % CI 0.28 to 1.31; p &lt; 0.01; I&lt;sup&gt;2&lt;/sup&gt; = 99.2%) and one-arm studies 0.75 (95% CI 0.39 to 1.11; p &lt; 0.01; I&lt;sup&gt;2&lt;/sup&gt; = 86%), and there was significant heterogeneity among both study types. 

Subgroup analyses revealed that studies with direct interventions on sleep duration (i.e., specified the sleep schedule) had larger effects compared to indirect methods (coaching, educational approaches) and a greater number of curriculum components was associated with smaller effects. 

Results of this review demonstrate that sleep extension studies are effective at extending sleep in a variety of populations but improving the description of intervention methods and use of more rigorous study designs will improve the quality and reproducibility of this area of research. 

Copyright &copy; 2021
AN  - 2014457951
AU  - Baron,
AU  - K.
AU  - G.
AU  - Duffecy,
AU  - J.
AU  - Reutrakul,
AU  - S.
AU  - Levenson,
AU  - J.
AU  - C.
AU  - McFarland,
AU  - M.
AU  - M.
AU  - Lee,
AU  - S.
AU  - Qeadan,
AU  - F.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.smrv.2021.101532
L1  - internal-pdf://1755519432/Baron-2021-Behavioral interventions to extend.pdf
PY  - 2021
T2  - Sleep Medicine Reviews
TI  - Behavioral interventions to extend sleep duration: A systematic review and meta-analysis
UR  - http://www.elsevier.com/inca/publications/store/6/2/3/0/7/4/index.htt
VL  - 60 (no pagination)
ER  -
TY  - JOUR
AB  - This study synthesized 14 published and unpublished group design and single-case design studies on bullying interventions for individuals with disabilities. The specific objectives were to examine the general characteristics and design qualities of the studies, quantify the magnitude of the intervention effects, and identify potential moderating variables. Four studies were excluded from the meta-analysis due to being outliers or having insufficient data. The design qualities of the 14 studies were assessed before conducting the meta-analysis. Analysis of the study characteristics revealed that approximately one-third of the studies included participants with a singular diagnosis, many of the participants were elementary or secondary high school age, researcher was the most common implementer, schools were the most common setting, and interventions targeted bully victims more than bullies themselves. The results indicated that six studies (43%) met the What Works Clearinghouse Design Standards, with or without reservations. The overall effect size for bullying intervention with individuals with disabilities was small, and effect size of individual studies was small to large. Interventions implemented by teachers had the largest effect size; however, no statistical significance was found across implementers. Implications for practice and future research are discussed in the following areas: implementer, dose of intervention, and implementation supports.
AN  - WOS:000751568100001
AU  - Maxfield,
AU  - T.
AU  - Park,
AU  - E.
AU  - Y.
AU  - Blair,
AU  - K.
AU  - S.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10864-021-09466-x
L1  - internal-pdf://3073900857/Synthesis of Bullying Interventions for Indivi.pdf
PY  - 2021
SP  - 26
T2  - Journal of Behavioral Education
TI  - Synthesis of Bullying Interventions for Individuals with Disabilities: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000751568100001
UR  - https://link.springer.com/content/pdf/10.1007/s10864-021-09466-x.pdf
ER  -
TY  - JOUR
AB  - This systematic review evaluates the efficacy of various early interventions on maternal emotional outcomes, mother-infant interaction, and subsequent infant outcomes during neonatal intensive care unit admission and postdischarge. Key interventions associated with outcomes in both the neonatal intensive care unit and postdischarge (ie, home) settings are summarized. 

A comprehensive search of peer-reviewed randomized controlled trials involving early interventions for infants and their mother published between 1993 and 2013 in the electronic databases PubMed, CINAHL, EMBASE, PsychINFO, and Cochrane was undertaken. Methodological quality was assessed using the PEDro scale to evaluate internal and external validity of the study. 

Twelve randomized controlled trials were included in the review, and all used some form of parenting education. The interventions had limited effects on maternal stress and mother-infant interaction and positive effects on maternal anxiety, depressive symptoms, and maternal coping. There were positive effects on infants&#039; short-term outcomes for length of stay and breast-feeding rate. 

Positive and clinically meaningful effects of early interventions were seen in some physiological/psychological outcomes of mothers and preterm infants. It is important for nurses to foster close mother-infant contact and increase maternal competence during and after the infant&#039;s hospitalization period. Lippincott Williams &amp; Wilkins.
AN  - 25408293
AU  - Zhang,
AU  - X.
AU  - Kurtz,
AU  - M.
AU  - Lee,
AU  - S.
AU  - Y.
AU  - Liu,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/JPN.0000000000000065
L1  - internal-pdf://0154390275/Zhang-2021.pdf
PY  - 2021
SP  - E69-E82
T2  - Journal of Perinatal &amp; Neonatal Nursing
TI  - Early Intervention for Preterm Infants and Their Mothers: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25408293
VL  - 35
ER  -
TY  - JOUR
AB  - **Background**: Pain is a disagreeable and distressing feeling that affects human beings in multi-dimensional ways. A number of non-pharmacological interventions have had varying degrees of success in treating cancer-related pain, such as breathing and relaxation techniques, and music therapy, which have been identified as beneficial therapies for alleviating pain and anxiety. 

**Objective(s)**: Identify the therapeutic effects of music interventions in psychological and physiological terms and on the quality of life of children undergoing cancer treatment. 

**Method(s)**: Systematic review of effectiveness based on the methodology of the Joanna Briggs Institute. 

**Result(s)**: Eleven articles were included with a total of 429 children, whose ages ranged from 0 to 18 years. The mean duration of the music intervention was 30.6 (+/-SD 9.8) min. In a combined estimate of five studies for pain and anxiety outcomes, there were benefits to using music when compared with the control group (SMD -1.05; CI 95 % -1.70 - 0.40 N = 453 I&lt;sup&gt;2&lt;/sup&gt; = 90 %). A combined analysis of five studies to assess quality of life showed that the use of music was favorable when compared with the control (SMD -0.80; CI 95 % -1.17-0.43 N = 457= I&lt;sup&gt;2&lt;/sup&gt; = 71 %). Conclusion(s): After completing this review, it was determined that there is evidence to support the use of music to reduce pain and anxiety and improve the quality of life of children undergoing cancer treatment. Copyright &copy; 2021 The Authors
AD  - (da Silva Santa) Pediatrics Department of the School of Medicine of the University of Sao Paulo (FMUSP), Av. Dr Eneas Carvalho Aguiar No. 647, Cerqueira Cesar, Sao Paulo CEP: 05403-901, Brazil (Schveitzer) Department of Preventive Medicine of the Paulista School of Medicine of the Federal University of Sao Paulo (UNIFEST-EPM), Rua Botucatu 740, Vila Clementino, Sao Paulo CEP: 04023-062, Brazil (dos Santos) Pediatric Intensive Therapy Center of the Children&#039;s Institute of the Clinical Hospital (HC) of FMUSP. Av, Dr Eneas Carvalho Aguiar No. 647, Cerqueira Cesar, Sao Paulo CEP: 05403-901, Brazil (Ghelman) Integrative Pediatrics Unit of the Pediatrics Department of the University of Sao Paulo, Brazilian Academic Consortium for Integrative Health (CABSIn) in collaboration with the Pan American Health Organization/World Health Organization, Rua Alvinlandia No. 345, Alto de Pinheiros, Sao Paulo CEP: 05449-070, Brazil (Filho) Pediatrics Department of the University of Sao Paulo, Av. Dr Eneas Carvalho Aguiar No. 647, Cerqueira Cesar, Sao Paulo CEP: 05403-901, BrazilI.N. da Silva Santa, Av. Engenheiro Heitor Antonio Eiras Garcia, 1927, Apto 74 bloco C1, Jardim Esmeralda, Sao Paulo CEP: 05588-001, Brazil. E-mail: Ivone.santa@hc.fm.usp.br
AN  - 2012051984
AU  - da
AU  - Silva
AU  - Santa,
AU  - I.
AU  - N.
AU  - Schveitzer,
AU  - M.
AU  - C.
AU  - dos
AU  - Santos,
AU  - M.
AU  - L.
AU  - B.
AU  - M.
AU  - Ghelman,
AU  - R.
AU  - Filho,
AU  - V.
AU  - O.
DA  - June
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ctim.2021.102725
DP  - Ovid Technologies
KW  - Anxiety
KW  - Children
KW  - Complementary medicine
KW  - Heart rate
KW  - Infant
KW  - Integrative medicine
KW  - Music
KW  - Oncology
KW  - Pain
KW  - adult
KW  - alternative medicine
KW  - cancer therapy
KW  - child
KW  - controlled study
KW  - female
KW  - human
KW  - male
KW  - quality of life
KW  - review
KW  - systematic review
KW  - young adult
L1  - internal-pdf://1961452553/da Silva Santa-2021.pdf
LA  - English
M3  - Review
PY  - 2021
T2  - Complementary Therapies in Medicine
TI  - MUSIC INTERVENTIONS IN PEDIATRIC ONCOLOGY: Systematic review and meta-analysis
UR  - http://www.elsevier.com/wps/find/journaldescription.cws_home/623020/authorinstructions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2012051984
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33964406&amp;id=doi:10.1016%2Fj.ctim.2021.102725&amp;issn=0965-2299&amp;isbn=&amp;volume=59&amp;issue=&amp;spage=102725&amp;pages=&amp;date=2021&amp;title=Complementary+Therapies+in+Medicine&amp;atitle=MUSIC+INTERVENTIONS+IN+PEDIATRIC+ONCOLOGY%3A+Systematic+review+and+meta-analysis&amp;aulast=da+Silva+Santa&amp;pid=%3Cauthor%3Eda+Silva+Santa+I.N.%3C%2Fauthor%3E%3CAN%3E2012051984%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 59 (no pagination)
ER  -
TY  - JOUR
AB  - Antipsychotic medications are used in a wide range of mental health and neurodevelopmental conditions in children and adolescents. Their efficacy and tolerability with long-term use have not been clearly established. We aimed to conduct a systematic review and meta-analysis to evaluate the long-term use of antipsychotics in children and adolescents. All relevant double-blind randomized control trials (RCTs), on any antipsychotic used for 12 weeks or longer in any mental health/neurodevelopmental condition in this age group, were included. We evaluated several efficacy and tolerability measures. Meta-analysis was performed for adverse events. Seven RCTs were identified (n = 939, age = 5-17 years), four on aripiprazole and three on risperidone. All studies reported symptomatic/functional improvements or more time before discontinuation with antipsychotics compared to placebo. Weight gain was identified as a significant side effect with antipsychotics. Serum prolactin was reduced with aripiprazole and increased with risperidone, and abdominal pain/discomfort, respiratory tract infections, were more common with Aripiprazole compared to placebo. Musculoskeletal pain may be more common with aripiprazole compared to placebo. Use of antipsychotics for 12 weeks or longer may be associated with symptomatic/functional improvements, but may be associated with additional side effects compared to short-term treatment. Further research in this population is needed.erdi
AN  - 34027855
AU  - Singappuli,
AU  - P.
AU  - Sonuga-Barke,
AU  - E.
AU  - Kyriakopoulos,
AU  - M.
DA  - May 24
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1017/S1092852921000523
DP  - Ovid Technologies
J2  - CNS Spectr
L1  - internal-pdf://1876456236/Singappuli-2021.pdf
LA  - English
N1  - Singappuli, PushpikaSonuga-Barke, EdmundKyriakopoulos, Marinos
PY  - 2021
SP  - 1-47
T2  - Cns Spectrums
TI  - Antipsychotic Long-Term Treatment in Children and Young People: A Systematic Review and Meta-Analysis of Efficacy and Tolerability Across Mental Health and Neurodevelopmental Conditions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34027855
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:34027855&amp;id=doi:10.1017%2FS1092852921000523&amp;issn=1092-8529&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-47&amp;date=2021&amp;title=Cns+Spectrums&amp;atitle=Antipsychotic+Long-Term+Treatment+in+Children+and+Young+People%3A+A+Systematic+Review+and+Meta-Analysis+of+Efficacy+and+Tolerability+Across+Mental+Health+and+Neurodevelopmental+Conditions.&amp;aulast=Singappuli&amp;pid=%3Cauthor%3ESingappuli+P%3C%2Fauthor%3E%3CAN%3E34027855%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/54C2C896FE1901EB4D2A02EAF2A75BE0/S1092852921000523a.pdf/div-class-title-antipsychotic-long-term-treatment-in-children-and-young-people-a-systematic-review-and-meta-analysis-of-efficacy-and-tolerability-across-mental-health-and-neurodevelopmental-conditions-div.pdf
ER  -
TY  - GEN
AB  - Sammendrag
Innledning
Mange opplever seksuelle overgrep i løpet av livet. Utøver er oftest en i bekjentskapskretsen eller en i familien. Forholdet mellom voldsutsatt og overgriper kan ha stor betydning for hvordan volden oppleves og for hvordan hjelpeapparatet best kan gripe inn og behandle. 

Nasjonalt kunnskapssenter om vold og traumatisk stress (NKVTS) har tidligere kartlagt behandlingstilbudet til voksne som utøver vold i Norge. De fant at utøvelse av seksuell vold er den formen for vold som behandles av færrest behandlingsenheter og at behandlingstilbudet til voksne med spesifikke problemer knyttet til utøvelse av seksuell vold, ikke er tilgjengelig i store deler av landet. Mange av behandlingsmetodene som benyttes i dag har ikke dokumentert effekt og det er behov for mer forskningsbasert kunnskap om effekt av behandlingstiltak. Hensikten med denne systematiske oversikten var å undersøke effekter av behandlingstiltak for personer som utøver seksuell vold i nære relasjoner. 

Problemstilling
Hva er effekten av behandlingstiltak for å forhindre gjentatte voldshendelser hos personer som utøver seksuell vold i nære relasjoner?

Metode
Vi utførte en systematisk oversikt over primærstudier. Vi søkte i relevante databaser i desember 2020. Vi inkluderte randomiserte studier og ikke-randomiserte intervensjonsstudier. To forskere gikk igjennom alle titler og sammendrag og deretter relevante artikler i fulltekst, og de vurderte risiko for systematiske skjevheter i de inkluderte studiene. Vi beskrev resultatene fra hver enkelt studie for seg, da det ikke var mulig å sammenstille dem i metaanalyser. Vi vurderte tilliten til resultatene for hovedutfallet, seksuell vold, ved hjelp av verktøyet GRADE (Grading of Recommendations Assessment, Development, and Evaluation.

Resultat
Vi inkluderte tre randomiserte og fem ikke-randomiserte studier som undersøkte ulike relevante tiltak. De randomiserte studiene var fra USA og Norge og hadde til sammen 656 deltakere (99,5 % menn). To av studiene omhandlet behandling av voksne personer og &eacute;n omhandlet behandling av ungdom. De ikke-randomiserte studiene var fra USA, Australia og Nederland og hadde til sammen 712 deltakere (98,6 % gutter/menn). Fire studier omhandlet behandling av voksne menn og &eacute;n barn/ungdom i alderen 10-17 år. Deltakerne i studiene hadde hovedsakelig begått vold mot familiemedlemmer eller bekjente.  

De randomiserte studiene undersøkte effekten av: Duluth-modellen sammenlignet med ingen behandling for menn som hadde begått partnervold målt med Conflict Tactics Scale (CTS2); multisystemisk terapi sammenlignet med gruppebasert kognitiv adferdsterapi for ungdom med seksuell skadelig adferd, målt med Adolescent Sexual Behaviour Inventory (ASBI); og gruppebasert kognitiv adferdsterapi sammenlignet med mindfulness-basert stressreduksjon for menn som hadde utøvd partnervold, målt med CTS2. De ikke-randomiserte studiene undersøkte effekten av: pretrial diversion sammenlignet med ingen behandling for menn som utøvde seksuell vold mot barn i familien, målt med strafferettslige opplysninger; spesialisert behandling i primærhelsetjenesten sammenlignet med ingen behandling for ungdom med seksuell skadelig adferd målt med strafferettslige opplysninger; gruppebasert kognitiv adferdsterapi sammenlignet med gruppebasert støttende terapi for menn som hadde utøvd partnervold, målt med CTS2; og Stichting Ambulante Preventie Projecten og et gruppebasert behandlingstiltak sammenlignet med ingen behandling for menn som hadde begått seksuell vold hovedsakelig mot familiemedlemmer og bekjente, målt med strafferettslige opplysninger.
AU  - Hestevik,
AU  - Christine
AU  - Hillestad
AU  - Muller,
AU  - Ashley
AU  - Elizabeth
AU  - Forsetlund,
AU  - Louise
DB  - My EndNote Library.enl
DO  - https://www.fhi.no/publ/2021/behandlingstiltak-for-personer-som-utover-seksuell-vold-i-nare-relasjoner/
N1  - https://www.fhi.no/globalassets/dokumenterfiler/rapporter/2021/behandlingstiltak-for-personer-som-utover-seksuell-vold-i-nare-relasjoner-rapport-2021.pdf
PY  - 2021
TI  - Behandlingstiltak for personer som utøver seksuell vold i nære relasjoner: en systematisk oversikt
ER  -
TY  - JOUR
AB  - This multi-level meta-analysis tested if evidence-based trauma treatment was effective in reducing trauma symptoms and externalizing behavior problems in adolescents. Based on eight independent samples and 75 effect sizes, results indicated that Trauma Focused-Cognitive Behavioral Therapy (TF-CBT) and Eye Movement Desensitization Reprocessing (EMDR) had a large and significant overall effect (d = 0.909) on reducing trauma symptoms and externalizing behavior problems. Trauma treatment significantly decreased trauma symptoms (large effect) and externalizing behavior problems (medium effect). Age and type of control group moderated treatment effects. Treatment was more effective in older adolescents. Trauma treatment for adolescents with externalizing behavior problems had a larger effect compared to no treatment, but not compared to treatment as usual. It seems important to provide a broad treatment offer for adolescents with severe externalizing behavior problems, in which, besides trauma treatment, attention is paid to reducing relevant individual risk factors for behavior problems.
AD  - Hoogsteder, Larissa M. Forensic Care Specialists, Utrecht, The Netherlands.Ten Thije, Lotte. University of Amsterdam, The Netherlands.Schippers, Eveline E. Forensic Care Specialists, Utrecht, The Netherlands.Stams, Geert Jan J M. University of Amsterdam, The Netherlands.
AN  - 33899551
AU  - Hoogsteder,
AU  - L.
AU  - M.
AU  - Ten
AU  - Thije,
AU  - L.
AU  - Schippers,
AU  - E.
AU  - E.
AU  - Stams,
AU  - G.
AU  - J.
AU  - J.
AU  - M.
DA  - Apr 26
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/0306624X211010290
DP  - Ovid Technologies
J2  - Int J Offender Ther Comp Criminol
L1  - internal-pdf://4287660779/Hoogsteder-2021.pdf
LA  - English
N1  - Hoogsteder, Larissa MTen Thije, LotteSchippers, Eveline EStams, Geert Jan J M
PY  - 2021
SP  - 306624X211010290
T2  - International Journal of Offender Therapy &amp; Comparative Criminology
TI  - A Meta-Analysis of the Effectiveness of EMDR and TF-CBT in Reducing Trauma Symptoms and Externalizing Behavior Problems in Adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33899551
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33899551&amp;id=doi:10.1177%2F0306624X211010290&amp;issn=0306-624X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=306624X211010290&amp;pages=306624X211010290&amp;date=2021&amp;title=International+Journal+of+Offender+Therapy+%26+Comparative+Criminology&amp;atitle=A+Meta-Analysis+of+the+Effectiveness+of+EMDR+and+TF-CBT+in+Reducing+Trauma+Symptoms+and+Externalizing+Behavior+Problems+in+Adolescents.&amp;aulast=Hoogsteder&amp;pid=%3Cauthor%3EHoogsteder+LM%3C%2Fauthor%3E%3CAN%3E33899551%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/10.1177/0306624X211010290
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0306624X211010290
ER  -
TY  - JOUR
AB  - **Background** 
Living with type 1 diabetes can be associated with significant psychological morbidity, poor glycaemic control, and increased risk for microvascular complications. This systematic review sought to investigate the effects of psychological interventions on depression, anxiety, diabetes-related distress, quality of life, and glycaemic control in people with type 1 diabetes. 

**Methods** 
Eight electronic databases were searched for published and unpublished randomised controlled trials. Screening, data extraction, and risk of bias assessment (using the Cochrane Collaboration tool for assessing risk of bias 2.0) were independently undertaken by two study authors. The results of the studies were meta-analysed, implementing a random-effects model. The Grading of Recommendations Assessment and Development and Evaluation (GRADE) system was used to determine the confidence in the effect estimates. 

**Results** 
Twenty studies were identified. Non-significant standardised mean differences (SMD) were found for depression symptoms (SMD = - 0.17, 95% CI [- 0.41, 0.07], p = 0.16) and diabetes-related distress (SMD = - 0.12, 95% CI [- 0.27, 0.04], p = 0.13). Significant SMD was found for quality of life (SMD = 0.27, 95% CI [0.11, 0.42], p = 0.0007). Significant mean difference (MD) was found for HbA1c (MD = - 0.26, 95% CI [- 0.51, - 0.01], p = 0.04). Prespecified subgroup analysis for cognitive behaviour-based interventions showed significant improvement for HbA1c (MD = - 0.23, 95% CI [- 0.44, - 0.02], p = 0.03). 

**Conclusions** 
Psychological interventions were found to significantly increase quality of life and promote glucose control in people with type 1 diabetes. Depending on their cost-effectiveness, psychological interventions could be incorporated in routine clinical practice for people with type 1 diabetes and concomitant psychological morbidity.
AN  - WOS:000749128600001
AU  - Efthymiadis,
AU  - A.
AU  - Bourlaki,
AU  - M.
AU  - Bastounis,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s13340-021-00564-9
L1  - internal-pdf://3611697572/The effectiveness of psychological interventio.pdf
PY  - 2021
SP  - 9
T2  - Diabetology International
TI  - The effectiveness of psychological interventions on mental health and quality of life in people living with type 1 diabetes: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000749128600001
UR  - https://link.springer.com/content/pdf/10.1007/s13340-021-00564-9.pdf
ER  -
TY  - JOUR
AB  - Attention deficit/hyperactivity disorder (ADHD) is one of the most frequent neurodevelopmental disorders in childhood and adolescence. Choosing the right treatment is critical to controlling and improving symptoms. 

An innovative ADHD treatment is neurofeedback (NF) that trains participants to self-regulate brain activity. The aim of the study was to analyze the effects of NF interventions in children with ADHD. 

A systematic review was carried out in the CINAHL, Medline (PubMed), Proquest, and Scopus databases, following the PRISMA recommendations. Nine articles were found. 

The NF improved behavior, allowed greater control of impulsivity, and increased sustained attention. In addition, it improved motor control, bimanual coordination and was associated with a reduction in theta waves. NF combined with other interventions such as medication, physical activity, behavioral therapy training, or attention training with brain-computer interaction, reduced primary ADHD symptoms. 

Furthermore, more randomized controlled trials would be necessary to determine the significant effects.
AN  - 34501246
AU  - Sampedro
AU  - Baena,
AU  - L.
AU  - Fuente,
AU  - G.
AU  - A.
AU  - C.
AU  - Martos-Cabrera,
AU  - M.
AU  - B.
AU  - Gomez-Urquiza,
AU  - J.
AU  - L.
AU  - Albendin-Garcia,
AU  - L.
AU  - Romero-Bejar,
AU  - J.
AU  - L.
AU  - Suleiman-Martos,
AU  - N.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/jcm10173797
L1  - internal-pdf://3957667073/Sampedro Baena-2021-Effects of Neurofeedback i.pdf
PY  - 2021
SP  - 25
T2  - Journal of Clinical Medicine
TI  - Effects of Neurofeedback in Children with Attention-Deficit/Hyperactivity Disorder: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=34501246
UR  - https://mdpi-res.com/d_attachment/jcm/jcm-10-03797/article_deploy/jcm-10-03797-v2.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **Purpose** The purpose of this systematic review was to identify, appraise, and critically synthesize the latest available evidence on the effects of augmentative and alternative communication (AAC)-based interventions on communication skills in children aged between 6 and 10 years with mixed diagnoses. 

**Method** MEDLINE (OVID), PsycINFO (EBSCO), ERIC (ProQuest), SCIELO (WOS), Teacher Reference Center (EBSCO), and Education Database (ProQuest) were searched. The studies were independently selected by two reviewers for the purposes of the review. The methodological quality of the included studies was assessed, and characteristics and results of the studies were extracted. 

**Results** This review included 14 studies from a total of 1,204 found through an electronic search. The AAC interventions studied were effective at improving various outcomes in children with mixed diagnoses. Interventions that focused on narrative skills were the most common type. When considering the quality of the studies, the independence of assessors, data analysis, replication, and generalization of interventions were the weaker areas. 

**Conclusions** Interventions analyzed in this review improve communication skills, including phonological awareness, vocabulary, requesting, and developing narrative skills in children aged between 6 and 10 years with mixed diagnoses. The results of one study also indicate that the acquisition of skills using an AAC method is superior when the child prefers the method. Supplemental Material https://doi.org/10.23641/asha.14462256.
AN  - 33909476
AU  - Langarika-Rocafort,
AU  - A.
AU  - Mondragon,
AU  - N.
AU  - I.
AU  - Etxebarrieta,
AU  - G.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1044/2021_LSHSS-20-00005
L1  - internal-pdf://2686662522/Langarika-Rocaf-2021-A Systematic Review of Re.pdf
PY  - 2021
SP  - 899-916
T2  - Language, Speech &amp; Hearing Services in the Schools
TI  - A Systematic Review of Research on Augmentative and Alternative Communication Interventions for Children Aged 6-10 in the Last Decade
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=33909476
VL  - 52
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Community-based primary-level workers (PWs) are an important strategy for addressing gaps in mental health service delivery in low- and middle-income countries.&nbsp; OBJECTIVES: To evaluate the effectiveness of PW-led treatments for persons with mental health symptoms in LMICs, compared to usual care.&nbsp; SEARCH METHODS: MEDLINE, Embase, CENTRAL, ClinicalTrials.gov, ICTRP, reference lists (to 20 June 2019).&nbsp;&nbsp; SELECTION CRITERIA: Randomised trials of PW-led or collaborative-care interventions treating people with mental health symptoms or their&nbsp;carers&nbsp;in LMICs.&nbsp; PWs included: primary health professionals (PHPs), lay health workers (LHWs), community non-health professionals (CPs).&nbsp; 

**DATA COLLECTION AND ANALYSIS**: Seven conditions were&nbsp;identified&nbsp;apriori and analysed by disorder and&nbsp;PW&nbsp;examining recovery,&nbsp;prevalence,&nbsp;symptom change, quality-of-life (QOL), functioning, service use&nbsp;(SU),&nbsp;and adverse events (AEs).&nbsp; Risk ratios (RRs) were used for dichotomous outcomes; mean difference (MDs), standardised mean differences (SMDs), or mean change differences (MCDs) for continuous outcomes.&nbsp; For SMDs, 0.20 to 0.49&nbsp;represented small,&nbsp;0.50 to 0.79&nbsp;moderate, and &ge;0.80&nbsp;large clinical effects.&nbsp; Analysis timepoints: T1 (&lt;1 month), T2 (1-6 months), T3 ( &gt;6 months) post-intervention.&nbsp; 

**MAIN RESULTS**: Description of studies 95 trials&nbsp;(72 new since 2013)&nbsp;from 30 LMICs (25 trials from 13 LICs).&nbsp; Risk of bias Most common: detection bias, attrition bias (efficacy), insufficient protection against contamination.&nbsp; Intervention effects *Unless indicated, comparisons were usual care at&nbsp;T2.&nbsp; &quot;Probably&quot;, &quot;may&quot;,&nbsp;or&nbsp;&quot;uncertain&quot; indicates &quot;moderate&quot;, &quot;low,&quot; or &quot;very low&quot; certainty evidence.&nbsp;&nbsp; Adults with common mental disorders (CMDs) LHW-led interventions a. may increase recovery (2 trials, 308 participants; RR 1.29, 95%CI 1.06 to 1.56); b. may reduce prevalence (2 trials, 479 participants; RR 0.42, 95%CI 0.18 to 0.96); c. may reduce symptoms (4 trials, 798 participants; SMD -0.59, 95%CI -1.01 to -0.16); d. may improve QOL (1 trial, 521 participants; SMD 0.51, 95%CI 0.34 to 0.69); e. may slightly reduce functional impairment (3 trials, 1399 participants; SMD -0.47, 95%CI -0.8 to -0.15); f. may reduce AEs (risk of suicide ideation/attempts); g. may have uncertain effects on SU. Collaborative-care a. may increase&nbsp;recovery (5 trials, 804 participants; RR 2.26, 95%CI 1.50 to 3.43); b. may reduce prevalence although the actual effect range indicates it may have little-or-no effect (2 trials, 2820 participants; RR 0.57, 95%CI 0.32 to 1.01); c. may slightly reduce symptoms (6 trials, 4419 participants; SMD -0.35, 95%CI -0.63 to -0.08); d. may slightly improve QOL (6 trials, 2199 participants; SMD 0.34, 95%CI 0.16 to 0.53); e. probably has little-to-no effect on functional impairment (5 trials, 4216 participants; SMD -0.13, 95%CI -0.28 to 0.03); f. may reduce SU (referral to MH specialists);&nbsp; g. may have uncertain effects on AEs (death). Women with perinatal depression (PND) LHW-led interventions a. may increase recovery (4&nbsp;trials, 1243 participants; RR 1.29, 95%CI 1.08&nbsp;to 1.54); b. probably slightly reduce symptoms (5 trials, 1989 participants; SMD -0.26, 95%CI -0.37 to -0.14); c. may slightly reduce functional impairment (4 trials, 1856 participants; SMD -0.23, 95%CI -0.41 to -0.04); d. may have little-to-no effect on AEs (death);&nbsp; e. may have uncertain effects on SU. Collaborative-care a. has uncertain effects on symptoms/QOL/SU/AEs. Adults with post-traumatic stress (PTS) or CMDs in humanitarian settings LHW-led interventions a. may slightly reduce depression symptoms (5 trials, 1986 participants; SMD -0.36, 95%CI -0.56 to -0.15); b. probably slightly improve QOL (4 trials, 1918 participants; SMD -0.27, 95%CI -0.39 to -0.15); c. may have uncertain effects on symptoms (PTS)/functioning/SU/AEs. PHP-led interventions a. may reduce PTS symptom prevalence (1 trial, 313 participants; RR 5.50, 95%CI 2.50 to 12.10) and depression prevalence (1 trial, 313 participants; RR 4.60, 95%CI 2.10 to 10.08);&nbsp; b. may have uncertain effects on symptoms/functioning/SU/AEs. &nbsp; Adults with harmful/hazardous alcohol or substance use LHW-led interventions a. may increase recovery from harmful/hazardous alcohol use although the actual effect range indicates it may have little-or-no effect (4 trials, 872 participants; RR 1.28, 95%CI 0.94 to 1.74); b. may have little-to-no effect on the prevalence of methamphetamine use (1 trial, 882 participants; RR 1.01, 95%CI 0.91 to 1.13) and &nbsp;functional impairment (2 trials, 498 participants; SMD -0.14, 95%CI -0.32 to 0.03); c. probably slightly reduce risk of harmful/hazardous alcohol use (3 trials, 667 participants; SMD -0.22, 95%CI -0.32 to -0.11);&nbsp; d. may have uncertain effects on SU/AEs. PHP/CP-led interventions a. probably have little-to-no effect on recovery from harmful/hazardous alcohol use (3 trials, 1075 participants; RR 0.93, 95%CI 0.77 to 1.12) or&nbsp;QOL (1 trial, 560 participants; MD 0.00, 95%CI -0.10 to 0.10); b. probably slightly reduce risk of harmful/hazardous alcohol and substance use (2 trials, 705 participants; SMD -0.20, 95%CI -0.35 to -0.05; moderate-certainty evidence); c. may have uncertain effects on prevalence (cannabis use)/SU/AEs. PW-led interventions for alcohol/substance dependence a. may have uncertain effects.&nbsp; Adults with severe mental disorders *Comparisons were specialist-led care at T1. LHW-led interventions a. may have little-to-no effect on caregiver burden (1 trial, 253 participants; MD -0.04, 95%CI -0.18 to 0.11);&nbsp; b. may have uncertain effects on symptoms/functioning/SU/AEs.&nbsp; PHP-led or collaborative-care a. may reduce functional impairment (7 trials, 874 participants; SMD -1.13, 95%CI -1.78 to -0.47); b. may have uncertain effects on recovery/relapse/symptoms/QOL/SU.&nbsp; Adults with dementia and carers PHP/LHW-led carer interventions a. may have little-to-no effect on the severity of behavioural symptoms in dementia patients (2 trials, 134 participants; SMD -0.26, 95%CI -0.60 to 0.08); b. may reduce carers&#039; mental distress (2 trials, 134 participants; SMD -0.47, 95%CI -0.82 to -0.13);&nbsp; c. may have uncertain effects on QOL/functioning/SU/AEs. Children with PTS or CMDs LHW-led interventions a. may have little-to-no effect on PTS symptoms (3 trials, 1090 participants; MCD -1.34, 95%CI -2.83 to 0.14); b. probably have&nbsp;little-to-no effect on depression symptoms (3 trials, 1092 participants; MCD -0.61, 95%CI -1.23 to 0.02) or on functional impairment (3 trials, 1092 participants; MCD -0.81, 95%CI -1.48 to -0.13);&nbsp; c. may have little-or-no effect on AEs. CP-led interventions a. may have little-to-no effect on depression symptoms (2 trials, 602 participants; SMD -0.19, 95%CI -0.57 to 0.19) or on AEs;&nbsp; b. may have uncertain effects on recovery/symptoms(PTS)/functioning. 

**AUTHORS&#039; CONCLUSIONS**: PW-led interventions show promising benefits in improving outcomes for CMDs, PND, PTS, harmful alcohol/substance&nbsp;use, and dementia carers in LMICs.
AD  - Department of Primary Care and Mental Health, University of Liverpool, Liverpool, UK.Department of Family Medicine and Primary Care, The University of Hong Kong, Pokfulam, Hong Kong.Bellevue College, Bellevue, Washington, USA.Norwegian Institute of Public Health, Oslo, Norway.Department of Community Health Sciences, School of Medicine and School of Public Health, Patan Academy of Health Sciences, Lalitpur, Nepal.Division of Population Health, Health Services Research &amp; Primary Care, The University of Manchester, Manchester, UK.Department of Neurosciences, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy.Public Health Policy Evaluation Unit, School of Public Health, Imperial College London, London, UK.Cochrane Common Mental Disorders, Centre for Reviews and Dissemination, University of York, York, UK.Faculty of Medicine, University of Oslo, Oslo, Norway.Tehran University of Medical Sciences, Tehran, Iran.Cochrane Response, Cochrane, London, UK.Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.Health Systems Research Unit, South African Medical Research Council, Cape Town, South Africa.
AN  - 34352116
AU  - van
AU  - Ginneken,
AU  - N.
AU  - Chin,
AU  - W.
AU  - Y.
AU  - Lim,
AU  - Y.
AU  - C.
AU  - Ussif,
AU  - A.
AU  - Singh,
AU  - R.
AU  - Shahmalak,
AU  - U.
AU  - Purgato,
AU  - M.
AU  - Rojas-Garc&iacute;a,
AU  - A.
AU  - Uphoff,
AU  - E.
AU  - McMullen,
AU  - S.
AU  - Foss,
AU  - H.
AU  - S.
AU  - Thapa
AU  - Pachya,
AU  - A.
AU  - Rashidian,
AU  - L.
AU  - Borghesani,
AU  - A.
AU  - Henschke,
AU  - N.
AU  - Chong,
AU  - L.
AU  - Y.
AU  - Lewin,
AU  - S.
DA  - Aug 5
DB  - My EndNote Library.enl
DO  - 10.1002/14651858.CD009149.pub3
DP  - NLM
J2  - The Cochrane database of systematic reviews
LA  - eng
N1  - 1469-493xvan Ginneken, NadjaChin, Weng YeeLim, Yen ChianUssif, AminSingh, RakeshShahmalak, UjalaPurgato, MariannaRojas-Garc&iacute;a, AntonioUphoff, EleonoraMcMullen, SarahFoss, Hakan SafaraliloThapa Pachya, AmbikaRashidian, LalehBorghesani, AnnaHenschke, NicholasChong, Lee-YeeLewin, SimonJournal ArticleResearch Support, Non-U.S. Gov&#039;tReviewCochrane Database Syst Rev. 2021 Aug 5;8(8):CD009149. doi: 10.1002/14651858.CD009149.pub3.
PY  - 2021
SP  - Cd009149
T2  - Cochrane Database Syst Rev
TI  - Primary-level worker interventions for the care of people living with mental disorders and distress in low- and middle-income countries
VL  - 8
ER  -
TY  - JOUR
AB  - **Background** Problem-solving training is a common ingredient of evidence-based therapies for youth depression and has shown effectiveness as a versatile stand-alone intervention in adults. This scoping review provided a first overview of the evidence supporting problem solving as a mechanism for treating depression in youth aged 14 to 24 years. 

**Methods** Five bibliographic databases (APA PsycINFO, CINAHL, Embase, MEDLINE, Web of Science) and the grey literature were systematically searched for controlled trials of stand-alone problem-solving therapy; secondary analyses of trial data exploring problem-solving-related concepts as predictors, moderators, or mediators of treatment response within broader therapies; and clinical practice guidelines for youth depression. Following the scoping review, an exploratory meta-analysis examined the overall effectiveness of stand-alone problem-solving therapy. 

**Results** Inclusion criteria were met by four randomized trials of problem-solving therapy (524 participants); four secondary analyses of problem-solving-related concepts as predictors, moderators, or mediators; and 23 practice guidelines. The only clinical trial rated as having a low risk of bias found problem-solving training helped youth solve personal problems but was not significantly more effective than the control at reducing emotional symptoms. An exploratory meta-analysis showed a small and non-significant effect on self-reported depression or emotional symptoms (Hedges&#039; g = - 0.34; 95% CI: - 0.92 to 0.23) with high heterogeneity. Removing one study at high risk of bias led to a decrease in effect size and heterogeneity (g = - 0.08; 95% CI: - 0.26 to 0.10). A GRADE appraisal suggested a low overall quality of the evidence. Tentative evidence from secondary analyses suggested problem-solving training might enhance outcomes in cognitive-behavioural therapy and family therapy, but dedicated dismantling studies are needed to corroborate these findings. Clinical practice guidelines did not recommend problem-solving training as a stand-alone treatment for youth depression, but five mentioned it as a treatment ingredient. 

**Conclusions** On its own, problem-solving training may be beneficial for helping youth solve personal challenges, but it may not measurably reduce depressive symptoms. Youth experiencing elevated depressive symptoms may require more comprehensive psychotherapeutic support alongside problem-solving training. High-quality studies are needed to examine the effectiveness of problem-solving training as a stand-alone approach and as a treatment ingredient.
AN  - WOS:000687667300001
AU  - Krause,
AU  - K.
AU  - R.
AU  - Courtney,
AU  - D.
AU  - B.
AU  - Chan,
AU  - B.
AU  - W.
AU  - C.
AU  - Bonato,
AU  - S.
AU  - Aitken,
AU  - M.
AU  - Relihan,
AU  - J.
AU  - Prebeg,
AU  - M.
AU  - Darnay,
AU  - K.
AU  - Hawke,
AU  - L.
AU  - D.
AU  - Watson,
AU  - P.
AU  - Szatmari,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12888-021-03260-9
L1  - internal-pdf://1622226060/Krause-2021-Problem-solving training as an act.pdf
PY  - 2021
SP  - 14
T2  - BMC Psychiatry
TI  - Problem-solving training as an active ingredient of treatment for youth depression: a scoping review and exploratory meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000687667300001
UR  - https://bmcpsychiatry.biomedcentral.com/track/pdf/10.1186/s12888-021-03260-9.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - UCLA PEERS for Adolescents is a widely applied program among a number of social skills training programs developed over the years. We synthesized current research evidence on the PEERS program to evaluate the treatment effect on four commonly used outcome measures. 12 studies met inclusion criteria for the review and nine met the criteria for meta-analysis. Results showed moderate to large pooled effects across measures and informants in favor of the PEERS program, with the largest effect seen in social knowledge improvement and the smallest effect in the frequency of get-togethers. The heterogeneity of effects across studies were examined and the limitations of the current evidence were discussed. Copyright &copy; 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.
AD  - (Zheng, Kim, Salzman, Ankenman, Bent) Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California San Francisco, 401 Parnassus Ave, San Francisco, CA 94143, United States (Bent) Department of Medicine, University of California San Francisco, San Francisco, CA, United States (Bent) Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, United StatesS. Zheng, Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California San Francisco, 401 Parnassus Ave, San Francisco, CA 94143, United States. E-mail: Shuting.Zheng@ucsf.edu
AN  - 2010298667
AU  - Zheng,
AU  - S.
AU  - Kim,
AU  - H.
AU  - Salzman,
AU  - E.
AU  - Ankenman,
AU  - K.
AU  - Bent,
AU  - S.
DA  - Februar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-021-04885-1
DP  - Ovid Technologies
KW  - Adolescents
KW  - Autism
KW  - Effect sizes
KW  - Meta-analysis
KW  - Social skills training
KW  - adolescent
KW  - article
KW  - effect size
KW  - female
KW  - human
KW  - male
KW  - meta analysis
KW  - outcome assessment
KW  - social competence
KW  - systematic review
L1  - internal-pdf://2244460537/Zheng-2021-Improving Social Knowledge and Skil.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2021
PY  - 2021
T2  - Journal of Autism and Developmental Disorders.
TI  - Improving Social Knowledge and Skills among Adolescents with Autism: Systematic Review and Meta-Analysis of UCLA PEERS for Adolescents
UR  - http://www.wkap.nl/journalhome.htm/0162-3257
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010298667
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33512626&amp;id=doi:10.1007%2Fs10803-021-04885-1&amp;issn=0162-3257&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2021&amp;title=Journal+of+Autism+and+Developmental+Disorders&amp;atitle=Improving+Social+Knowledge+and+Skills+among+Adolescents+with+Autism%3A+Systematic+Review+and+Meta-Analysis+of+UCLA+PEERS+for+Adolescents&amp;aulast=Zheng&amp;pid=%3Cauthor%3EZheng+S.%3C%2Fauthor%3E%3CAN%3E2010298667%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s10803-021-04885-1.pdf
ER  -
TY  - JOUR
AB  - Acute and chronic psychological distress are prevalent during adolescence and can have negative impacts on adolescents in all life domains. 

The aim of this systematic review was to appraise the use of virtual reality (VR) interventions to manage symptoms of psychological distress symptoms among adolescents. MEDLINE, PubMed, PsycINFO, and Scopus databases were searched up to June 2020. 

Available citations were de-duplicated and screened by two authors using title and abstract information. A total of 301 articles were retained for full-text evaluation next to eligibility criteria. Empirical studies of all designs and comparator groups were included if these appraised the impact of an immersive VR intervention on any standardized measure indicative of psychological distress in an adolescent sample. 

Data were extracted into a standardized coding sheet. Results were tabulated and discussed with a narrative synthesis due to the heterogeneity between studies. A total of seven studies met inclusion criteria. There were four randomized controlled trials and three uncontrolled pilot studies on new VR interventions. Distress-related issues included: state-anxiety, venepuncture, risk taking, public speaking anxiety, social anxiety disorder, sexual victimization, and chemotherapy administration. 

All studies reported significant changes on outcome measures after VR treatment. Six studies reported small-to-large reductions in symptoms. The average attrition rate was 3.6 percent during the active VR treatment phase. Treatment acceptability was high in the studies that assessed user engagement factors. The VR technology can provide a safe, rapidly efficacious, and acceptable treatment modality for managing psychological distress in several key adolescent populations.
AN  - 34558970
AU  - Kelson,
AU  - J.
AU  - N.
AU  - Ridout,
AU  - B.
AU  - Steinbeck,
AU  - K.
AU  - Campbell,
AU  - A.
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1089/cyber.2021.0090
L1  - internal-pdf://3547472968/Kelson-2021-The Use of Virtual Reality for Man.pdf
PY  - 2021
SP  - 24
T2  - Cyberpsychology, behavior and social networking
TI  - The Use of Virtual Reality for Managing Psychological Distress in Adolescents: Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34558970
VL  - 24
ER  -
TY  - JOUR
AB  - Inhibitory control is a main component of executive functions that relate to the ability to control prepotent responses and to resist interferences. Deficits in inhibitory control have been associated with numerous disorders, but exercise has become a promising approach to benefit this domain. This systematic review and meta-analysis aims to provide synthesized information and effect size calculations of the benefits of chronic exercise interventions on the inhibitory control of healthy children and adolescents. A systematic search of PubMed, PsycINFO, MEDLINE, ERIC, SPORTDiscus, and PsycArticles identified 4166 articles to be screened for eligibility. A total of 10 studies (3138 participants) met the inclusion criteria. A random-effects analysis model was performed in three variables: accuracy, reaction time and combined scores. The results showed a very small but statistically significant effect in accuracy (d = 0.14, 95% CI 0.01 to 0.27, P =.04), and two almost null effects (statistically non-significant), in the reaction time (d = 0.03, 95% CI -0.10 to 0.16, P =.62) and the combined scores (d = 0.06, 95% CI -0.03 to 0.15, P =.17). Despite the high number of studies that reported positive outcomes, this meta-analysis found only modest benefits in the inhibitory control of healthy children and adolescents after they participated in different chronic exercise interventions. The strict inclusion criteria of this study and the high variability in the designs of the exercise interventions included, among other reasons, might explain the obtained results.
AN  - WOS:000626909800001
AU  - Amatriain-Fernandez,
AU  - S.
AU  - Garcia-Noblejas,
AU  - M.
AU  - E.
AU  - Budde,
AU  - H.
DA  - JUN
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/sms.13934
L1  - internal-pdf://1726295713/Amatriain-Fernandez-2021.pdf
PY  - 2021
SP  - 1196-1208
T2  - SCANDINAVIAN JOURNAL OF MEDICINE &amp; SCIENCE IN SPORTS
TI  - Effects of chronic exercise on the inhibitory control of children and adolescents: A systematic review and meta-analysis
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/sms.13934?download=true
VL  - 31
ER  -
TY  - JOUR
AB  - This meta-analysis evaluated the current state of evidence and identified potential treatment moderators of the Incredible Years Teacher Classroom Management (IYTCM) program used to reduce externalizing and internalizing behaviors in school-aged children. 

Inclusion criteria involved published studies between 1984-2018 and examining the effects of IYTCM as a standalone program on teacher and/or child behavioral outcomes. We identified and narratively summarized potential moderators, which included the severity of child behavior, dosage, study design, and reporting methods. 

Overall, effect sizes revealed IYTCM had moderate positive effects on teachers and small positive effects on children. Narrative summaries indicated larger effect sizes in higher dosage studies and higher risk children. The results align with previous systematic reviews on the Incredible Years Parent Training (IYPT) program but this is the first study to look at the teacher training program. 

Overall, IYTCM seems to be an effective intervention; however, what components of this program work best, for whom, and under what conditions require further empirical investigation.
AN  - 35053649
AU  - Korest,
AU  - R.
AU  - Carlson,
AU  - J.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/children9010024
L1  - internal-pdf://4060061043/A Meta-Analysis of the Current State of E-2021.pdf
PY  - 2021
SP  - 30
T2  - Children
TI  - A Meta-Analysis of the Current State of Evidence of the Incredible Years Teacher-Classroom Management Program
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=35053649
UR  - https://mdpi-res.com/d_attachment/children/children-09-00024/article_deploy/children-09-00024.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - BACKGROUND: 
The net health benefit of using antipsychotics in children and adolescents with ASD is unclear. This review was performed to provide the evidence necessary to inform the Italian national guidelines for the management of ASD.

METHODS: 
We performed a systematic review of randomized controlled trials (RCTs) comparing antipsychotics versus placebo for the treatment of ASD in children and adolescents. For efficacy, acceptability and safety we considered outcomes evaluated by the guideline panel critical and important for decision-making. Continuous outcomes were analyzed by using standardized mean difference (SMD), and dichotomous outcomes by calculating the risk ratio (RR), with their 95% confidence interval (95% CI). Data were analyzed using a random effects model. We used the Cochrane tool to assess risk of bias of included studies. Certainty in the evidence of effects was assessed according to the GRADE approach.

RESULTS: 
We included 21 RCTs with 1,309 participants, comparing antipsychotics to placebo. Antipsychotics were found effective on &quot;restricted and repetitive interests and behaviors&quot; (SMD - 0.21, 95% CI - 0.35 to - 0.07, moderate certainty), &quot;hyperactivity, inattention, oppositional, disruptive behavior&quot; (SMD - 0.67, 95% CI - 0.92 to - 0.42, moderate certainty), &quot;social communication, social interaction&quot; (SMD - 0.38, 95% CI - 0.59 to - 0.16, moderate certainty), &quot;emotional dysregulation/irritability&quot; (SMD - 0.71, 95% CI - 0.98 to - 0.43, low certainty), &quot;global functioning, global improvement&quot; (SMD - 0.64, 95% CI - 0.96 to - 0.33, low certainty), &quot;obsessions, compulsions&quot; (SMD - 0.30, 95% CI - 0.55 to - 0.06, moderate certainty). Antipsychotics were not effective on &quot;self-harm&quot; (SMD - 0.14, 95% CI - 0.58 to 0.30, very low certainty), &quot;anxiety&quot; (SMD - 0.38, 95% CI - 0.82 to 0.07, very low certainty). Antipsychotics were more acceptable in terms of dropout due to any cause (RR 0.61, 95% CI 0.48 to 0.78, moderate certainty), but were less safe in terms of patients experiencing adverse events (RR 1.19, 95% CI 1.07 to 1.32, moderate certainty), and serious adverse events (RR 1.07, 95% CI 0.48 to 2.43, low certainty).

CONCLUSIONS: 
Our systematic review and meta-analysis found antipsychotics for children and adolescents with ASD more efficacious than placebo in reducing stereotypies, hyperactivity, irritability and obsessions, compulsions, and in increasing social communication and global functioning. Antipsychotics were also found to be more acceptable, but less safe than placebo.
AD  - D&#039;Alo, Gian Loreto. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy. gianloretod@gmail.com.De Crescenzo, Franco. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.De Crescenzo, Franco. Department of Psychiatry, University of Oxford, Oxford, UK.De Crescenzo, Franco. Pediatric University Hospital-Department (DPUO), Bambino Gesu Children&#039;s Hospital, Rome, Italy.Amato, Laura. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Cruciani, Fabio. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Davoli, Marina. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Fulceri, Francesca. Research Coordination and Support Service, Istituto Superiore Di Sanita, Viale Regina Elena 299, 00161, Rome, Italy.Minozzi, Silvia. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Mitrova, Zuzana. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Morgano, Gian Paolo. Research Coordination and Support Service, Istituto Superiore Di Sanita, Viale Regina Elena 299, 00161, Rome, Italy.Nardocci, Franco. Research Coordination and Support Service, Istituto Superiore Di Sanita, Viale Regina Elena 299, 00161, Rome, Italy.Saulle, Rosella. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Schunemann, Holger Jens. Department of Health Research Methods, Evidence and Impact (Formerly Clinical Epidemiology and Biostatistics), McMaster GRADE Centre, McMaster University, Hamilton, ON, Canada.Schunemann, Holger Jens. Department of Medicine, McMaster University, Hamilton, ON, Canada.Scattoni, Maria Luisa. Research Coordination and Support Service, Istituto Superiore Di Sanita, Viale Regina Elena 299, 00161, Rome, Italy.
AN  - 33494757
AU  - D&#039;Alo,
AU  - G.
AU  - L.
AU  - De
AU  - Crescenzo,
AU  - F.
AU  - Amato,
AU  - L.
AU  - Cruciani,
AU  - F.
AU  - Davoli,
AU  - M.
AU  - Fulceri,
AU  - F.
AU  - Minozzi,
AU  - S.
AU  - Mitrova,
AU  - Z.
AU  - Morgano,
AU  - G.
AU  - P.
AU  - Nardocci,
AU  - F.
AU  - Saulle,
AU  - R.
AU  - Schunemann,
AU  - H.
AU  - J.
AU  - Scattoni,
AU  - M.
AU  - L.
AU  - Isaca
AU  - Guideline
AU  - Working
AU  - Group
DA  - Jan 25
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12955-021-01669-0
DP  - Ovid Technologies
J2  - Health Qual Life Outcomes
L1  - internal-pdf://3274546213/D&#039;Alo-2021-Impact of antipsychotics in childre.pdf
LA  - English
N1  - D&#039;Alo, Gian LoretoDe Crescenzo, FrancoAmato, LauraCruciani, FabioDavoli, MarinaFulceri, FrancescaMinozzi, SilviaMitrova, ZuzanaMorgano, Gian PaoloNardocci, FrancoSaulle, RosellaSchunemann, Holger JensScattoni, Maria LuisaISACA Guideline Working GroupTancredi RMassagli AValeri GCappa CBuono SArduino GMZuddas AReali LMolteni MFelici CCordo CVenturini LBellosio CDi Tommaso EBiasci SDuff CMVecchi S
PY  - 2021
SP  - 33
T2  - Health &amp; Quality of Life Outcomes
TI  - Impact of antipsychotics in children and adolescents with autism spectrum disorder: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33494757
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33494757&amp;id=doi:10.1186%2Fs12955-021-01669-0&amp;issn=1477-7525&amp;isbn=&amp;volume=19&amp;issue=1&amp;spage=33&amp;pages=33&amp;date=2021&amp;title=Health+%26+Quality+of+Life+Outcomes&amp;atitle=Impact+of+antipsychotics+in+children+and+adolescents+with+autism+spectrum+disorder%3A+a+systematic+review+and+meta-analysis.&amp;aulast=D%27Alo&amp;pid=%3Cauthor%3ED%27Alo+GL%3C%2Fauthor%3E%3CAN%3E33494757%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://hqlo.biomedcentral.com/track/pdf/10.1186/s12955-021-01669-0.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - School physical activity breaks are currently being proposed as a way to improve students&#039; learning. However, there is no clear evidence of the effects of active school breaks on academic-related cognitive outcomes. 

The present systematic review with meta-analysis scrutinized and synthesized the literature related to the effects of active breaks on students&#039; attention. On January 12th, 2021, PubMed, PsycINFO, Scopus, SPORTDiscus, and Web of Science were searched for published interventions with counterbalanced cross-over or parallel-groups designs with a control group, including school-based active breaks, objective attentional outcomes, and healthy students of any age. Studies&#039; results were qualitatively synthesized, and meta-analyses were performed if at least three study groups provided pre-post data for the same measure. 

Results showed some positive acute and chronic effects of active breaks on attentional outcomes (i.e., accuracy, concentration, inhibition, and sustained attention), especially on selective attention. However, most of the results were not significant. The small number of included studies and their heterogeneous design are the primary limitations of the present study. Although the results do not clearly point out the positive effects of active breaks, they do not compromise students&#039; attention. The key roles of intensity and the leader of the active break are discussed. INPLASY registration number: 202110054.
AN  - WOS:000665350200001
AU  - Infantes-Paniagua,
AU  - A.
AU  - Silva,
AU  - A.
AU  - F.
AU  - Ramirez-Campillo,
AU  - R.
AU  - Sarmento,
AU  - H.
AU  - Gonzalez-Fernandez,
AU  - F.
AU  - T.
AU  - Gonzalez-Villora,
AU  - S.
AU  - Clemente,
AU  - F.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/brainsci11060675
L1  - internal-pdf://2272045571/Infantes-Paniag-2021-Active School Breaks and.pdf
PY  - 2021
SP  - 28
T2  - Brain Sciences
TI  - Active School Breaks and Students&#039; Attention: A Systematic Review with Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000665350200001
UR  - https://res.mdpi.com/d_attachment/brainsci/brainsci-11-00675/article_deploy/brainsci-11-00675-v2.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Background:** 
Anxiety disorder is the most prevalent mental disorder among children and adolescents, causing significant psychosocial problems and physical health conditions. Cognitive behavioral therapy (CBT) is an effective treatment for anxiety disorder in children and adolescents. And parent-only CBT is an alternative treatment for childhood anxiety disorder, which includes psychologists and parents rather than children in the treatment. As a new type of CBT, parent-only CBT has some advantages. However, it remains unclear whether parent-only CBT interventions are effective for treating children and adolescents with anxiety disorder. 

**Method(s):** 
In this study, we evaluated the efficacy (the mean change scores of the anxiety rating scale from baseline to post-treatment, standardized mean difference SMD) and acceptability (the proportion of patients in the treatment group who withdrew from treatment early for any reason, risk ratios RRs) of parent-only cognitive behavioral therapy (CBT) for children and adolescents with anxiety disorder. We searched electronic databases, including PubMed, Cochrane Library, Embase, Web of Science, ProQuest, and PsycINFO from inception to June 2019. We included randomized controlled trials (RCTs) comparing parent-only CBT either with waitlist (WL), or CBT with parents in children and adolescents with anxiety disorder. 

**Result(s):** 
Finally, six RCTs with 407 participants were included in the meta-analyses. In terms of efficacy, pooled analyses indicated that parent-only CBT was significantly more effective than WL for reducing anxiety symptoms with SMD of - 0.72 (95% CI - 1.41 to - 0.03, p = 0.04), and more remission rate with RR of 4.33 (37.96% vs. 6.85, 95% CI 1.82 to 10.27, p = 0.0009) at post-treatment. And our analyses showed no evidence that parent-only CBT had significantly greater efficacy than CBT with parents with SMD of 0.21 (95% CI - 0.09 to 0.50, p = 0.17). Acceptability in the parent-only CBT group was not significantly different to the WL group with RR of 0.92 (95% CI 0.52 to 1.62, p = 0.77), and was significantly worse than in the CBT with parents group with RR of 1.93 (95% CI 1.05 to 3.57, p = 0.03).

**Conclusion(s):** 
Current evidence indicates that parent-only CBT can be an alternative and acceptable intervention for treating children and adolescents with anxiety disorder. Copyright &copy; 2021, The Author(s).
AD  - (Yin) Department of Neurology, People&#039;s Hospital of Deyang City, Deyang, China (Yin, Teng, Li, Fan, Xie) Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China (Yin, Teng, Li, Fan, Xie) NHC Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital, Chongqing Medical University, No. 1 Youyi Road, Chongqing 400016, China (Tong) Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China (Zhou) Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Chongqing 400016, ChinaP. Xie, NHC Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital, Chongqing Medical University, No. 1 Youyi Road, Chongqing 400016, China. E-mail: xiepeng973@126.com X. Zhou, Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Chongqing 400016, China. E-mail: xinyu973@126.com
AN  - 2010153857
AU  - Yin,
AU  - B.
AU  - Teng,
AU  - T.
AU  - Tong,
AU  - L.
AU  - Li,
AU  - X.
AU  - Fan,
AU  - L.
AU  - Zhou,
AU  - X.
AU  - Xie,
AU  - P.
DA  - januar
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1186/s12888-020-03021-0
DP  - Ovid Technologies
KW  - Adolescent
KW  - Anxiety
KW  - Child
KW  - Meta-analysis
KW  - Parent-only CBT
KW  - anxiety disorder
KW  - article
KW  - Cochrane Library
KW  - cognitive behavioral therapy
KW  - comparative effectiveness
KW  - controlled study
KW  - Embase
KW  - female
KW  - human
KW  - male
KW  - Medline
KW  - meta analysis
KW  - PsycINFO
KW  - randomized controlled trial (topic)
KW  - rating scale
KW  - remission
KW  - risk assessment
KW  - systematic review
KW  - Web of Science
L1  - internal-pdf://0905295205/Yin-2021-Efficacy and acceptability of parent-.pdf
LA  - English
PY  - 2021
T2  - BMC Psychiatry
TI  - Efficacy and acceptability of parent-only group cognitive behavioral intervention for treatment of anxiety disorder in children and adolescents: a meta-analysis of randomized controlled trials
UR  - https://bmcpsychiatry.biomedcentral.com/
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010153857
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1186%2Fs12888-020-03021-0&amp;issn=1471-244X&amp;isbn=&amp;volume=21&amp;issue=1&amp;spage=29&amp;pages=&amp;date=2021&amp;title=BMC+Psychiatry&amp;atitle=Efficacy+and+acceptability+of+parent-only+group+cognitive+behavioral+intervention+for+treatment+of+anxiety+disorder+in+children+and+adolescents%3A+a+meta-analysis+of+randomized+controlled+trials&amp;aulast=Yin&amp;pid=%3Cauthor%3EYin+B.%3C%2Fauthor%3E%3CAN%3E2010153857%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://bmcpsychiatry.biomedcentral.com/track/pdf/10.1186/s12888-020-03021-0.pdf
VL  - 21 (1) (no pagination)
ER  -
TY  - JOUR
AB  - We conducted a systematic review to identify randomized controlled trials (RCTs) and single case research design (SCRD) studies of children with autism spectrum disorder that evaluate the effectiveness of responsivity intervention techniques for improving prelinguistic and/or language outcomes. 

Mean effect sizes were moderate and large for RCTs (33 studies; g = 0.36, 95% CI [0.21, 0.51]) and SCRD (34 studies; between-case standardized mean difference = 1.20, 95% CI [0.87, 1.54]) studies, respectively. Visual analysis (37 studies) revealed strong evidence of a functional relation for 45% of the opportunities and no evidence for 53%. Analyses of moderator effects and study quality are presented.

Findings provide support for responsivity intervention strategies with more robust support for context-bound outcomes than more generalized outcomes. Copyright &copy; 2021, The Author(s).
AN  - 2014195961
AU  - McDaniel,
AU  - J.
AU  - Brady,
AU  - N.
AU  - C.
AU  - Warren,
AU  - S.
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-021-05331-y
L1  - internal-pdf://3803495056/Effectiveness of Responsivity Interventio-2021.pdf
PY  - 2021
T2  - Journal of Autism and Developmental Disorders.
TI  - Effectiveness of Responsivity Intervention Strategies on Prelinguistic and Language Outcomes for Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis of Group and Single Case Studies
UR  - http://www.wkap.nl/journalhome.htm/0162-3257
UR  - https://link.springer.com/content/pdf/10.1007/s10803-021-05331-y.pdf
ER  -
TY  - JOUR
AB  - There is a current escalating need for telehealth (TH) options in family mental health services. In the absence of replicated evidence, TH guidelines from peak bodies are largely based on assumptions of the effectiveness of TH methods. New investments in TH would optimally be based in evidence of clinical efficacy. To this end, we conducted three studies in which we (1) systematically reviewed eight professional guidelines for TH family therapy, (2) examined replicated evidence for the efficacy of TH family therapy through systematic review of 20 studies and meta-analyses of 13 effects, and (3) synthesised clinical accommodations to TH methodology from a study of 12 experienced TH family therapists. The studies found (1) a predominant focus in existing TH guidelines on operational matters pertaining to TH and relative neglect of therapeutic process; (2) meta-analyses of efficacy for child behavioural problems (k = 8) and parental depression (k = 5) showed equivalent outcomes in TH and face-to-face therapy and enhanced outcomes in TH relative to treatment as usual, resource provision (i.e. written materials), or wait-list control. Narrative review of 20 studies for a range of relational and mental health outcomes aligned with these findings; and (3) therapists defined clear conditions for enhanced engagement and therapeutic process via TH and reflected on cautions and accommodations for purposes of rapport building and mitigating risk. Given moderate-strong evidence for the efficacy of TH methods of family therapy for a range of conditions, we offer recommendations for future implementation of TH for family therapy.
AN  - WOS:000611439700001
AU  - McLean,
AU  - S.
AU  - A.
AU  - Booth,
AU  - A.
AU  - T.
AU  - Schnabel,
AU  - A.
AU  - Wright,
AU  - B.
AU  - J.
AU  - Painter,
AU  - F.
AU  - L.
AU  - McIntosh,
AU  - J.
AU  - E.
DA  - JUN
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-020-00340-2
L1  - internal-pdf://0188438125/McLean-2021.pdf
PY  - 2021
SP  - 244-266
T2  - CLINICAL CHILD AND FAMILY PSYCHOLOGY REVIEW
TI  - Exploring the Efficacy of Telehealth for Family Therapy Through Systematic, Meta-analytic, and Qualitative Evidence
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829321/pdf/10567_2020_Article_340.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - **BACKGROUND**: Sequalae of opioid misuse constitute a public health emergency in the United States. A robust evidence base informs the use of medication for opioid use disorders (MOUD) in adults, with far less research in transition-age youth. This systematic review evaluates the effectiveness of MOUD for transition-age youth (age 16 to 25). 

**METHODS**: This synthesis was part of a larger systematic review focused on adolescent substance use interventions. The study team conducted literature searches in MEDLINE, the Cochrane CENTRAL Registry of Controlled Trials, EMBASE, PsycINFO, and CINAHL through October 31, 2019. We screened studies, extracted data, and assessed risk of bias using standard methods. The primary and secondary outcomes were the effect of MOUD on opioid abstinence and treatment retention, respectively. 

**RESULTS**: The study team screened a total of 33,272 records and examined 1831 full-text articles. Four randomized trials met criteria for inclusion in the current analysis. All four trials assessed a combination of buprenorphine plus cognitive behavioral therapy versus a comparison condition. Some trials included additional behavioral interventions, and the specific duration/dosage of buprenorphine varied. Risk of bias was moderate for all studies. Studies found that buprenorphine was more effective than clonidine, effectively augmented by memantine, and that longer medication taper durations were more effective than shorter tapers in promoting both abstinence and retention. Notably, we did not identify any studies of methadone or naltrexone, adjunctive behavioral interventions were sparingly described, and treatment durations were far shorter than recommended guidelines in adults. 

**DISCUSSION**: The literature guiding youth MOUD is limited, and more research should evaluate the effectiveness of options other than buprenorphine, optimal treatment duration, and the benefit of adjunctive behavioral interventions. Subgroup analyses of extant randomized clinical trials could help to extend knowledge of MOUD effectiveness in this age cohort.
AN  - 34098208
AU  - Becker,
AU  - S.
AU  - J.
AU  - Scott,
AU  - K.
AU  - Helseth,
AU  - S.
AU  - A.
AU  - Danko,
AU  - K.
AU  - J.
AU  - Balk,
AU  - E.
AU  - M.
AU  - Saldanha,
AU  - I.
AU  - J.
AU  - Adam,
AU  - G.
AU  - P.
AU  - Steele,
AU  - D.
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jsat.2021.108494
L1  - internal-pdf://1434472772/Becker-2021-Effectiveness of medication for op.pdf
PY  - 2021
SP  - 108494
T2  - Journal of Substance Abuse Treatment
TI  - Effectiveness of medication for opioid use disorders in transition-age youth: A systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34098208
UR  - https://www.journalofsubstanceabusetreatment.com/article/S0740-5472(21)00220-8/fulltext
VL  - 132
ER  -
TY  - JOUR
AB  - Juvenile awareness programs, such as Scared Straight, remain in use despite the finding that these programs provoke rather than prevent delinquency. 

The aim of this study was to examine what program components are associated with program effectiveness, which is important for improving these programs. A three-level meta-analysis was conducted. A literature search yielded 13 independent studies (N = 1,536) from which 88 effect sizes could be extracted. 

A nonsignificant overall effect was found (d = 0.10), indicating that juvenile awareness programs have no effect on offending behavior and other outcomes that are related to delinquency. 

No significant moderator effects were found for program components. The moderator analyses revealed that juvenile awareness programs are effective in reducing antisocial attitudes (d = 0.46), which has not been meta-analytically studied before. 

Furthermore, larger effects were found as follow-up length increased. These results show a more nuanced view on the effectiveness of juvenile awareness programs is necessary.
AN  - 32114866
AU  - van
AU  - der
AU  - Put,
AU  - C.
AU  - E.
AU  - Boekhout
AU  - van
AU  - Solinge,
AU  - N.
AU  - F.
AU  - Stams,
AU  - G.
AU  - J.
AU  - Hoeve,
AU  - M.
AU  - Assink,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/0306624X20909239
L1  - internal-pdf://1135164516/van der Put-2021-Effects of Awareness Programs.pdf
PY  - 2021
SP  - 68-91
T2  - International Journal of Offender Therapy &amp; Comparative Criminology
TI  - Effects of Awareness Programs on Juvenile Delinquency: A Three-Level Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=32114866
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0306624X20909239
VL  - 65
ER  -
TY  - JOUR
AB  - PROBLEM: 
Psychological and symptom disturbances seriously affect hospitalized children&#039;s subjective experiences of hospitalization and their prognosis. We systematically reviewed the effects of animal-assisted therapy (AAT) on pain, anxiety, depression, stress, blood pressure (BP), and heart rate (HR) in hospitalized children and teenagers.

ELIGIBILITY CRITERIA: 
A systematic review and meta-analysis were conducted using the English-language electronic databases PubMed, EMBASE, Web of Science, the Cochrane Library, Clinical Trials, Science Direct, EBSCOhost, Open Grey and Google Scholar, and the Chinese databases CNKI, Sinomed, Vip, and WanFang. These databases were searched through July 15, 2020.SAMPLE: Eight studies, including four randomized controlled trials (RCTs) and four quasi-experimental studies were included, with a total of 348 participants.

RESULTS: 
Hospitalized children and teenagers with AAT had less pain (standardized mean difference = -0.49; 95% confidence interval [CI], -0.77 to -0.22; P &lt; 0.001), lower systolic blood pressure (mean difference [MD] = -4.85; 95% CI, -9.50 to -0.21; P&lt;sub&gt;=&lt;/sub&gt; 0.04), higher diastolic blood pressure (MD = 4.95; 95% CI, 1.90 to 8.00; P&lt;sub&gt;= 0.001)&lt;/sub&gt; than controls, while there was no significant difference in depression, anxiety, stress, or HR.

CONCLUSION: 
As an adjuvant to traditional treatment, AAT was beneficial for controlling pain and BP in hospitalized children and teenagers.IMPLICATION: AAT may be an effective strategy for relieving pain and controlling BP in hospitalized children and teenagers, especially those with cancer. High-quality RCTs conducted or supported by nurses on the effects of AAT are needed.
AD  - Feng, Yongshen. School of Nursing, Sun Yat-sen University, Guangzhou 510080, China. Electronic address: 1396783110@qq.com.Lin, Yeqing. Research Management Department, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China. Electronic address: linyq77@mail2.sysu.edu.cn.Zhang, Ningning. School of Nursing, Sun Yat-sen University, Guangzhou 510080, China. Electronic address: zhbning@163.com.Jiang, Xiaohan. School of Nursing, Sun Yat-sen University, Guangzhou 510080, China. Electronic address: 732693042@qq.com.Zhang, Lifeng. School of Nursing, Sun Yat-sen University, Guangzhou 510080, China. Electronic address: zhlfeng@mail.sysu.edu.cn.
AN  - 33582447
AU  - Feng,
AU  - Y.
AU  - Lin,
AU  - Y.
AU  - Zhang,
AU  - N.
AU  - Jiang,
AU  - X.
AU  - Zhang,
AU  - L.
DA  - Feb 11
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.pedn.2021.01.020
DP  - Ovid Technologies
J2  - J Pediatr Nurs
L1  - internal-pdf://1055829793/Feng-2021-Effects of animal-assisted therapy o.pdf
LA  - English
M3  - Review
N1  - Feng, YongshenLin, YeqingZhang, NingningJiang, XiaohanZhang, LifengS0882-5963(21)00023-3
PY  - 2021
SP  - 11-23
T2  - Journal of Pediatric Nursing
TI  - Effects of animal-assisted therapy on hospitalized children and teenagers: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33582447
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33582447&amp;id=doi:10.1016%2Fj.pedn.2021.01.020&amp;issn=0882-5963&amp;isbn=&amp;volume=60&amp;issue=&amp;spage=11&amp;pages=11-23&amp;date=2021&amp;title=Journal+of+Pediatric+Nursing&amp;atitle=Effects+of+animal-assisted+therapy+on+hospitalized+children+and+teenagers%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Feng&amp;pid=%3Cauthor%3EFeng+Y%3C%2Fauthor%3E%3CAN%3E33582447%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.pediatricnursing.org/article/S0882-5963(21)00023-3/pdf
VL  - 60
ER  -
TY  - JOUR
AB  - BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) is the most common childhood-onset neurodevelopmental disorder, and methylphenidate (MPH) is considered one of the first-line medicine for ADHD. Unfortunately, this medication is only effective for some children with ADHD. This meta-analysis was conducted to evaluate whether noradrenergic gene polymorphisms impact the efficacy of MPH in children with ADHD. 

METHODS: Candidate gene studies published in English until March 1, 2020, were identified through literature searches on PubMed, Web of Science, and Embase. Data were pooled from individual clinical trials considering MPH pharmacogenomics. According to the heterogeneity, the odds ratio and mean differences were calculated by applying fixed-effects or random-effects models. 

RESULTS: This meta-analysis includes 15 studies and 1382 patients. Four polymorphisms of the NET gene (rs5569, rs28386840, rs2242446, rs3785143) and 2 polymorphisms of the alpha2A-adrenergic receptor gene (ADRA2A) gene (MspI and DraI) were selected for the analysis. In the pooled data from all studies, T allele carriers of the rs28386840 polymorphism were significantly more likely to respond to MPH (P &lt; .001, ORTcarriers = 2.051, 95% confidence interval [CI]:1.316, 3.197) and showed a relationship with significantly greater hyperactive-impulsive symptoms improvement (P &lt; .001, mean difference:1.70, 95% CI:0.24, 3.16). None of the ADRA2A polymorphisms correlated significantly with MPH response as a whole. However, G allele carriers of the MspI polymorphism showed a relationship with significantly inattention symptoms improvement (P &lt; .001, mean difference:0.31, 95% CI: 0.15, 0.47). 

CONCLUSION: Our meta-analysis results indicate that the noradrenergic gene polymorphisms may impact MPH response. The NET rs28386840 is linked to improved MPH response in ADHD children. And the ADRA2A MspI is associated with inattention symptom improvements. Further investigations with larger samples will be needed to confirm these results.Registration: PROSPERO (no. CRD42021265830).
AN  - 34797323
AU  - Yuan,
AU  - D.
AU  - Zhang,
AU  - M.
AU  - Huang,
AU  - Y.
AU  - Wang,
AU  - X.
AU  - Jiao,
AU  - J.
AU  - Huang,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/MD.0000000000027858
L1  - internal-pdf://3326921577/Noradrenergic genes polymorphisms and res-2021.pdf
PY  - 2021
SP  - e27858
T2  - Medicine
TI  - Noradrenergic genes polymorphisms and response to methylphenidate in children with ADHD: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=34797323
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8601359/pdf/medi-100-e27858.pdf
VL  - 100
ER  -
TY  - JOUR
AB  - Psychological interventions have been proven to be effective to prevent depression, however, little is known on the cost-effectiveness of psychological interventions for the prevention of depression in various populations. A systematic review was conducted using PubMed, PsycINFO, Web of Science, Embase, Cochrane Central Register of Controlled Trials, Econlit, NHS Economic Evaluations Database, NHS Health Technology Assessment and OpenGrey up to January 2021. Only health-economic evaluations based on randomized controlled trials of psychological interventions to prevent depression were included. Independent evaluators selected studies, extracted data and assessed the quality using the Consensus on Health Economic Criteria and the Cochrane Risk of Bias Tool. Twelve trial-based economic evaluations including 5929 participants from six different countries met the inclusion criteria. Overall, the quality of most economic evaluations was considered good, but some studies have some risk of bias. Setting the willingness-to-pay upper limit to US$40,000 (2018 prices) for gaining one quality adjusted life year (QALY), eight psychological preventive interventions were likely to be cost-effective compared to care as usual. The likelihood of preventive psychological interventions being more cost-effective than care as usual looks promising, but more economic evaluations are needed to bridge the many gaps that remain in the evidence-base. Ethics: As this systematic review is based on published data, approval from the local ethics committee was not required. Copyright &copy; 2021 Elsevier Ltd
AN  - 2013690589
AU  - Conejo-Ceron,
AU  - S.
AU  - Lokkerbol,
AU  - J.
AU  - Moreno-Peral,
AU  - P.
AU  - Wijnen,
AU  - B.
AU  - Fernandez,
AU  - A.
AU  - Mendive,
AU  - J.
AU  - M.
AU  - Smit,
AU  - F.
AU  - Bellon,
AU  - J.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.cpr.2021.102064
L1  - internal-pdf://2764874591/Conejo-Ceron-2021.pdf
PY  - 2021
T2  - Clinical Psychology Review
TI  - Health-economic evaluation of psychological interventions for depression prevention: Systematic review
UR  - http://www.elsevier.com/locate/clinpsychrev
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0272735821001070?via%3Dihub
VL  - 88 (no pagination)
ER  -
TY  - JOUR
AB  - Meta-analyses show that psychotherapies are effective in the treatment of depression in children and adolescents. However, these effects are usually reported in terms of effect sizes. For patients and clinicians, it is important to know whether patients achieve a clinically significant improvement or deterioration. We conducted such a meta-analysis to examine response, clinically significant change, clinically significant deterioration and recovery as outcomes. We searched four bibliographic databases and included 40 randomised trials comparing psychotherapy for youth depression against control conditions. We used a validated method to estimate outcome rates, based on means, standard deviation and N at baseline and post-test. We also calculated numbers-need-to- treat (NNT). The overall response rate in psychotherapies at 2 (+/-1) months after baseline was 39% (95% CI: 34-45) and 24% (95% CI: 0.19-28) in control conditions (NNT: 6.2). The difference between therapy and control was still significant at 6-12 months after baseline (NNT=7.8). Clinically significant improvement was found in 54% of youth in therapy, compared with 32% in control groups (NNT=5.3); clinically significant deterioration was 6% in therapy, 13% in controls (NNT=5.1); recovery was 58% in therapy, 36% in controls (NNT=3.3). Smaller effects were found in studies with low risk of bias. Psychotherapies for depression in youth are effective compared to control conditions, but more than 60% of youth receiving therapy do not respond. More effective treatments and treatment strategies are clearly needed. Trial registrationhttps://osf.io/84xka (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-92427-001
AU  - Cuijpers,
AU  - P.
AU  - Karyotaki,
AU  - E.
AU  - Ciharova,
AU  - M.
AU  - Miguel,
AU  - C.
AU  - F.
AU  - Noma,
AU  - H.
AU  - Stikkelbroek,
AU  - Y.
AU  - A.
AU  - J.
AU  - Weisz,
AU  - J.
AU  - R.
AU  - Furukawa,
AU  - T.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-021-01884-6
L1  - internal-pdf://2545734164/Cuijpers-2021-The effects of psychological tre.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - European Child &amp; Adolescent Psychiatry
TI  - The effects of psychological treatments of depression in children and adolescents on response, reliable change, and deterioration: A systematic review and meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-92427-001
UR  - https://link.springer.com/content/pdf/10.1007/s00787-021-01884-6.pdf
ER  -
TY  - JOUR
AB  - **Background**: Procedural pain and anxiety in children can be poorly controlled, leading to significant short- and long-term sequelae, such as longer procedure times or future healthcare avoidance. Caregiver anxiety can exacerbate these effects. We aimed to evaluate the effect of interactive video game interventions on children&#039;s procedural pain and anxiety, including the effect of different types of video games on those outcomes. 

**Method(s)**: We conducted a systematic review and meta-analysis of the effectiveness of interactive video games compared with standard care in children (0-18 yr) undergoing painful procedures. We searched the databases MEDLINE, Embase, and PsycINFO. We conducted random-effects meta-analysis using &#039;R&#039; of children&#039;s procedural pain and anxiety and caregivers&#039; anxiety. 

**Result(s)**: Of 2185 studies screened, 36 were eligible (n=3406 patients). Studies commonly involved venous access (33%) or day surgery (31%). Thirty-four studies were eligible for meta-analyses. Interactive video games appear to reduce children&#039;s procedural pain (standardised mean difference [SMD]=-0.43; 95% confidence interval [CI]: -0.67 to -0.20), anxiety (SMD=0.61; 95% CI: -0.88 to -0.34), and caregivers&#039; procedural anxiety (SMD=-0.31; 95% CI: -0.58 to -0.04). We observed no difference between preparatory and distracting games, or between virtual reality and non-virtual reality games. We also observed no difference between interactive video games compared with standard care for most medical outcomes (e.g. procedure length), except a reduced need for restraint. Studies reported minimal adverse effects and typically had high intervention acceptability and satisfaction. 

**Conclusion(s)**: Our findings support introducing easily available video games, such as distraction-based conventional video games, into routine practice to minimise paediatric procedural pain and child/caregiver anxiety. Copyright &copy; 2021 British Journal of Anaesthesia
AN  - 2013846651
AU  - Sajeev,
AU  - M.
AU  - F.
AU  - Kelada,
AU  - L.
AU  - Yahya
AU  - Nur,
AU  - A.
AU  - B.
AU  - Wakefield,
AU  - C.
AU  - E.
AU  - Wewege,
AU  - M.
AU  - A.
AU  - Karpelowsky,
AU  - J.
AU  - Akimana,
AU  - B.
AU  - Darlington,
AU  - A.
AU  - S.
AU  - Signorelli,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.bja.2021.06.039
L1  - internal-pdf://0277563803/Sajeev-2021-Interactive video games to reduce.pdf
PY  - 2021
T2  - British Journal of Anaesthesia.
TI  - Interactive video games to reduce paediatric procedural pain and anxiety: a systematic review and meta-analysis
UR  - https://www.journals.elsevier.com/british-journal-of-anaesthesia
ER  -
TY  - JOUR
AB  - **Purpose**: A meta-analysis of group interventions to reduce post-traumatic stress symptoms (PTSS) and/or depression among refugee and immigrant children and adolescents. 

**Methods**: A systematic search was followed by independent reviews of each study for risk of bias. The meta-analysis pooled between- and within-condition effect sizes on PTSS and depression across studies using a random effects model. 

**Results**: The search yielded 16 studies utilizing eight interventions involving 976 participants. For all studies, within conditions, there were good effects on PTSS (d = -0.66, 95% CI [-0.86, -0.46]) and depression (d = -0.51, 95% CI [-0.79, -0.23]) with substantial heterogeneity. For studies with control groups, the between-group effect sizes yielded a small effect on PTSS (d = -0.31, 95% CI [-0.65, 0.03]) with no significant effect on depression. 

**Conclusions**: The interventions helped to reduce PTSS and depression. Most studies lacked rigorous designs and provided little information on group variables needed for replication.
AN  - WOS:000665231400001
AU  - Rafieifar,
AU  - M.
AU  - Macgowan,
AU  - M.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/10497315211022812
L1  - internal-pdf://3808286244/Rafieifar-A Meta-Analysis of Group Interventio.pdf
PY  - 2021
SP  - 19
T2  - Research on Social Work Practice
TI  - A Meta-Analysis of Group Interventions for Trauma and Depression Among Immigrant and Refugee Children
UR  - &lt;Go to ISI&gt;://WOS:000665231400001
UR  - https://journals.sagepub.com/doi/10.1177/10497315211022812
UR  - https://journals.sagepub.com/doi/pdf/10.1177/10497315211022812
ER  -
TY  - JOUR
AB  - **Objectives**
In recent years, the number of studies on the relationship between dispositional mindfulness (DM) facets and depression and anxiety symptoms has increased notably. The objective of this meta-analysis was to identify the longitudinal predictive associations from DM facets to depression and anxiety symptoms in both adult and adolescent samples.

**Methods**
Studies were eligible if they measured anxiety or depressive symptoms at least two times and DM during the first measurement. This meta-analysis seeks to clarify the proposed relationships, applying a Two-Stage Structural Equation Modeling method to data collected from adult and adolescent studies. In total, 34 studies were included.

**Results**
The results indicated that, in adult samples, the facets of Acting with Awareness, Non-Judging, Describing, and Non-Reacting covaried significantly with depression and anxiety symptoms at time one, but only Acting with Awareness and Non-Reacting facets predicted a decrease of symptoms over time. Due to the scarcity of studies using childhood and adolescent samples, only the role of Acting with Awareness predicting depression was evaluated, and the results indicated that this facet predicts a decrease in depression over time among adolescents.

**Conclusions**
These results provide insight into the longitudinal relationships between DM facets and depression and anxiety symptoms and suggest the importance of focusing attention on these facets in mindfulness interventions.

**Trial Registration**
The project was preregistered at the Open Science Framework (https://osf.io/ye4af).
AN  - 2021-88731-001
AU  - Prieto-Fidalgo,
AU  - A.
AU  - Gomez-Odriozola,
AU  - J.
AU  - Royuela-Colomer,
AU  - E.
AU  - Orue,
AU  - I.
AU  - Fernandez-Gonzalez,
AU  - L.
AU  - Onate,
AU  - L.
AU  - Cortazar,
AU  - N.
AU  - Iraurgi,
AU  - I.
AU  - Calvete,
AU  - E.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s12671-021-01756-9
L1  - internal-pdf://0051720395/Prieto-Fidalgo-2021-Predictive associations of.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Mindfulness
TI  - Predictive associations of dispositional mindfulness facets with anxiety and depression: A meta-analytic structural equation modeling approach
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-88731-001
UR  - https://link.springer.com/content/pdf/10.1007/s12671-021-01756-9.pdf
ER  -
TY  - JOUR
AB  - **Background** Programs to support parents are the recommended strategy to reduce disruptive child behavior problems. Efforts have been made to demonstrate which program components (i.e., clusters of techniques taught) increase program effects, but these methods fail to account for the fact that components rarely operate in isolation. We examine how combinations of components cluster together to form program types and use network meta-analysis to estimate the relative effects of these program types. 

**Methods** We updated an existing systematic review of parenting programs for disruptive child behavior and identified 197 randomized trials. We modeled clusters of components in each trial arm and chose the best-fitting model. We subsequently took 20 draws from the probability distribution of the latent class for each arm, entered each draw into a network meta-analysis model and combined findings using Rubin&#039;s rules. Combined estimates were bootstrapped to rank the clusters. We estimated main models and separate models for prevention and treatment settings. 

**Results** A five-class solution fit the data best: (1) behavior management; (2) behavior management with parental self-management; (3) behavior management with psychoeducation and relationship enhancement; (4) maximal component loading and (5) no/minimal component loading (i.e. control). In the main model and in treatment settings, all four program types were effective compared to no/minimal components. In prevention settings, only behavior management and behavior management with parental self-management were effective compared to no/minimal components. Probabilistic ranking showed that overall and in treatment settings, behavior management had the largest chance, and in prevention settings, behavior management with self-management had the largest chance, of being most effective compared to no/minimal components. 

**Conclusions** Programs with more focused content seem more likely to yield stronger effects, and different foci may be needed in treatment versus prevention settings. Next steps include identifying individual family differences in optimal program content. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-67710-001
AU  - Leijten,
AU  - P.
AU  - Melendez-Torres,
AU  - G.
AU  - Gardner,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13483
L1  - internal-pdf://1897969302/Leijten-2021-Research review_ The most effecti.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Journal of Child Psychology and Psychiatry
TI  - Research review: The most effective parenting program content for disruptive child behavior - a network meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-67710-001
UR  - https://acamh.onlinelibrary.wiley.com/doi/10.1111/jcpp.13483
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.13483?download=true
ER  -
TY  - JOUR
AB  - **CONTEXT**
It has been suggested that a gluten-free and casein-free (GFCF) diet may alleviate the symptoms of autism spectrum disorder (ASD) and facilitate neurodevelopment of children with ASD. Studies to date have been inconclusive. 

**OBJECTIVE**
This study aimed to evaluate (through quantitative meta-analysis) the efficacy and safety of a GFCF diet for children with ASD. To our knowledge, this is the first time such an analysis has been carried out. 

**DATA SOURCES**
Eight electronic databases were searched, from the establishment of each database up to March 27, 2020: PubMed, Web of Science, Embase (Ovid), PsycINFO (Ovid), Cochrane Library, CNKI, Wanfang, and VIP databases. 

**DATA EXTRACTION**
Two authors independently performed the data extraction and risk-of-bias assessment. 

**DATA ANALYSIS**
A quantitative meta-analysis was performed with standard procedures by using Stata SE 15 software. Within the total of 8 studies, with 297 participants, 5 studies reported significant reductions in stereotypical behaviors [standard mean difference (SMD) = -0.41, 95% confidence interval (CI): -0.68 to -0.15], and 3 studies reported improvements in cognition (SMD = -0.46, 95% CI: -0.91 to -0.01) following GFCF dietary intervention. No statistically significant changes were observed in other symptomatic categories (all P &gt; 0.05). 

**CONCLUSION**
The current meta-analysis showed that a GFCF diet can reduce stereotypical behaviors and improve the cognition of children with ASD. Though most of the included studies were single-blind, the benefits of a GFCF diet that have been indicated are promising. Additional studies on a larger scale are warranted. SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration no. CRD42020177619.
AN  - 34617108
AU  - Quan,
AU  - L.
AU  - Xu,
AU  - X.
AU  - Cui,
AU  - Y.
AU  - Han,
AU  - H.
AU  - Hendren,
AU  - R.
AU  - L.
AU  - Zhao,
AU  - L.
AU  - You,
AU  - X.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/nutrit/nuab073
L1  - internal-pdf://0287556009/Quan-2021-A systematic review and meta-analysi.pdf
PY  - 2021
SP  - 07
T2  - Nutrition Reviews
TI  - A systematic review and meta-analysis of the benefits of a gluten-free diet and/or casein-free diet for children with autism spectrum disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=34617108
UR  - https://watermark.silverchair.com/nuab073.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAvcwggLzBgkqhkiG9w0BBwagggLkMIIC4AIBADCCAtkGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM7hwOJAq_IbxD6y15AgEQgIICqmf-R4LR3gTOkTr1iowB8W0r4p5rYH49b8uV7Q_7cpv1iWb8Wa1MO1Qs3YS_NfpX4t8ucP_jEU60O5PQ8VIA3QQbWOw5PaD4M6TMfPQ6kOjXtCjC3ZgKpjStPm2l2d2t2KjMCRaQJwjxI4jZZ7tpXpYmo-YsJftD4lwF_exUNHcGFzJVuQHqd1c3K0wowxm1Td1eq3WawGfFOr_nEfaBxK1Xno1A6xT6VgNgZr5TV160MGNyOrlBFu6ZP8m84EhaO1is_ldwo0FyBBDM65R_2N3ivBdxypo2YM6t1RJEJ-A8yVwi6ePTtJ8rzh1U9U72jnh46ZMqkIRLiPFmu-zvn0VtZrw1584kEmt7KBdSq829VaoUjt_YBRHdlSyGL2VKLQ7iUIzrnVIMfoD-rpuBlXfyWuhdlmEzxcWTAvHSZup38SoQNDho7FOP32RHasVVi8hFqgdR8AFQXCHbdOeTvAjAgRbUKF_0JxcClsIZmvavkTbtCeLvRGCBYXRkkhszpRNBAmeDG_RMdno04WEzofqymFQorJUKxrr08FdHtbLLXI1_6JzqVl0L0amZDeYvuIzIprHVlnPsBu0VHZ2VtGmk8os5SpvvRwoCeZtRXMmeEK1INnoGACPf7a7ooWfq7Wt7DgKGxtpjHCxBeDb2uabcVslV5YL3G82uEoQ0P0ynTO5uivjTuq9xPAZ_vHx9BHVM1wy8Jm4EldXTS9FlZG64FM86VOxjTg73VVFKftmVsro6T47KgYv4F4ioD0yC6gttE9QzAfaV_rdE02XoZc5LcNbrQABa2OSmkA5O02ZSEwf1A5_jUHeQqpK_s8pOhWDsq_NV-6h6TVuojxMWN8q3MnSxeAaOH8PV1tPoA4JnZiO5L9G9b1Et1BDM3Wicuo6V51Hf7dULewE
VL  - 07
ER  -
TY  - JOUR
AB  - **Background **
Youth who reenter communities after forensic or residential care are overrepresented in prevalence rates for mental disorders, delinquency, incarceration, low academic achievement, and unemployment. Supportive interventions that aid youth in the reentry to their communities can be crucial for successful reintegration. In systematic reviews (SR) on this topic, only specific interventions or programs are described. Therefore, a summary of evidence about transitional interventions for various groups of reentry youth is needed. 

**Method **
This overview of SRs was preregistered in PROSPERO. We searched PsycINFO, Ovid MEDLINE, Cochrane Library, Campbell Library, Web of Science, Sociological Abstracts, Criminal Justice Abstracts, Social Care Online, and Epistemonikos. SRs that fit the search criteria were evaluated using the AMSTAR checklist for methodological quality and the GRADE tool for assessing confidence in effect estimates. 

**Results **
We screened 2,349 publications for eligibility. Eight SRs were included for analysis. The methodological quality of five SRs was critically low, two were of low quality, and one was of moderate quality. Recidivism was reported as the only outcome in five SRs. Detrimental outcomes were reported in five SRs. Confidence in effect estimates was low or very low for all outcomes. Ninety-five percent of primary study populations were from the United States. 

**Conclusion **
We offer a rigorous appraisal of SRs on transitional interventions. The gaps of knowledge are vast regarding what works, how it works, and for whom. Development of a knowledge base should include defining the term &#039;recidivism&#039;, systematic reporting of demographics, and identifying effective common elements. 

(PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-82591-001
AU  - Kvamme,
AU  - L.
AU  - S.
AU  - Waaler,
AU  - P.
AU  - Helland,
AU  - S.
AU  - S.
AU  - Kjobli,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/camh.12507
L1  - internal-pdf://1535255811/Kvamme-2021-Review_ Striving for happily ever.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Child and Adolescent Mental Health
TI  - Review: Striving for happily ever after - supportive interventions for youth leaving residential placement - a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-82591-001
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/camh.12507?download=true
ER  -
TY  - JOUR
AB  - **Introduction** 
Self-regulation has been identified as a highly promising target for interventions promoting broad wellbeing across development; however, there appear to be notable limitations in efficacy for early adolescents in particular. One possible reason is that the emotion regulation needs of youth have not been intentionally targeted in many interventions for this age group. 

The aim of this study is to advance understanding of how different intervention approaches defined from a clear theoretical model may impact different types of outcomes and with regard to different types of measures. 

**Methods** 
We conducted a systematic literature review of four databases using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and identified 33 studies of early adolescents (aged 10-15) using five different intervention approaches that were methodologically rigorous (e.g., randomized controlled trial design with low risk of bias). Studies were conducted predominantly in North America (58%), and Western Europe (30%). 

**Results** 
A two-level mixed-effects meta-analysis indicated a small but significant overall intervention effect (Hedges g = 0.12). When examined by intervention type, effects were significant only for approaches focusing predominantly on emotion regulation (g = 0.20), which significantly improved behavioral outcomes as well as emotional outcomes. Approaches examining cognitive regulation, parent training, physical activity, and working memory did not differ significantly from zero. Across intervention types, outcomes demonstrated the largest effects for youth report of emotional distress. 

**Conclusion** 
Overall, results suggest that emotion regulation may be a critically important self-regulation mechanism during early adolescence and demonstrates value in the use of applied theoretical frameworks to operationalize intervention approaches and outcomes.
AN  - WOS:000750994400001
AU  - Murray,
AU  - D.
AU  - W.
AU  - Kurian,
AU  - J.
AU  - Hong,
AU  - S.
AU  - L.
AU  - S.
AU  - Andrade,
AU  - F.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/jad.12010
L1  - internal-pdf://2560819873/Meta-analysis of early adolescent self-regulat.pdf
PY  - 2021
SP  - 17
T2  - Journal of Adolescence
TI  - Meta-analysis of early adolescent self-regulation interventions: Moderation by intervention and outcome type
UR  - &lt;Go to ISI&gt;://WOS:000750994400001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jad.12010?download=true
ER  -
TY  - JOUR
AB  - Research suggests that mentoring programs may promote a range of positive outcomes in youth populations. Less is known, however, about the extent to which such programs are effective in specialized youth populations, such as youth involved in the foster care system. 

The current study aimed to investigate the extent to which mentoring interventions promote positive outcomes among youth involved in the foster care system and to systematically explore factors that may moderate the effectiveness of mentoring interventions. Using a multilevel meta-analytic approach, this study estimated the effect size of nine formal mentoring programs in the United States serving youth involved with the foster care system (total n = 55,561). Analyses revealed a small-to-medium-sized overall effect (g = 0.342). Moderator analyses revealed weaker effects for studies containing higher proportions of youth with emotional abuse histories. Programs deploying near-peer mentors were more than twice as effective as intergenerational mentors. 

The findings highlight the salience of emotional abuse history, suggesting the utility of providing mentor trainings in trauma-informed care for this population. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2021-64893-001
AU  - Poon,
AU  - Cyanea
AU  - Y.
AU  - Christensen,
AU  - Kirsten
AU  - M.
AU  - Rhodes,
AU  - Jean
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10964-021-01472-6
L1  - internal-pdf://3778335105/Poon-2021-A meta-analysis of the effects of me.pdf
PY  - 2021
SP  - No Pagination Specified
T2  - Journal of Youth and Adolescence
TI  - A meta-analysis of the effects of mentoring on youth in foster care
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2021-64893-001
UR  - https://link.springer.com/content/pdf/10.1007/s10964-021-01472-6.pdf
ER  -
TY  - JOUR
AB  - LAY ABSTRACT: Early intensive applied behaviour analysis-based interventions are designed to support young autistic children&#039;s learning and development. Unfortunately, the available evidence about the effectiveness of these interventions remains unclear. Several reviews have focused on the published findings rather than contacting the authors to collect and analyse data about the individual participants in the original studies. Also, most of the studies were carried out by groups involved in delivering the interventions leading to the potential bias in interpreting the results. Our research team (supported by an international advisory group) carried out an independent individual patient data review by collecting the original participant data from the authors of the studies, to examine the effectiveness of these interventions. The results suggested that early intensive applied behaviour analysis-based interventions might lead to some changes in children&#039;s cognitive ability (intelligence quotient) and everyday life skills after 2 years, compared with standard treatments. However, all the studies had problems with the way they were designed. Also, few of the studies looked at outcomes that have been described as most important to autistic people or followed children beyond 2 years. We think that further systematic reviews of the existing evidence are unlikely to add to the findings of our review. Furthermore, we recommend that future research should investigate which types of supports and interventions are most effective for children and families, prioritising outcomes measures that are meaningful for the autism community and include, wherever possible, longer-term follow-up.
AD  - Rodgers, Mark. University of York, UK.Simmonds, Mark. University of York, UK.Marshall, David. University of York, UK.Hodgson, Robert. University of York, UK.Stewart, Lesley A. University of York, UK.Rai, Dheeraj. University of Bristol, UK.Wright, Kath. University of York, UK.Ben-Itzchak, Esther. Ariel University, Israel.Eikeseth, Svein. Oslo Metropolitan University, Norway.Eldevik, Sigmund. Oslo Metropolitan University, Norway.Kovshoff, Hanna. University of Southampton, UK.Magiati, Iliana. University of Western Australia (UWA), Australia.Osborne, Lisa A. Swansea Bay University Health Board, UK.Reed, Phil. Swansea University, UK.Vivanti, Giacomo. Drexel University, USA.Zachor, Ditza. Tel Aviv University, Israel.Couteur, Ann Le. Newcastle University, UK.
AN  - 33482692
AU  - Rodgers,
AU  - M.
AU  - Simmonds,
AU  - M.
AU  - Marshall,
AU  - D.
AU  - Hodgson,
AU  - R.
AU  - Stewart,
AU  - L.
AU  - A.
AU  - Rai,
AU  - D.
AU  - Wright,
AU  - K.
AU  - Ben-Itzchak,
AU  - E.
AU  - Eikeseth,
AU  - S.
AU  - Eldevik,
AU  - S.
AU  - Kovshoff,
AU  - H.
AU  - Magiati,
AU  - I.
AU  - Osborne,
AU  - L.
AU  - A.
AU  - Reed,
AU  - P.
AU  - Vivanti,
AU  - G.
AU  - Zachor,
AU  - D.
AU  - Couteur,
AU  - A.
AU  - L.
DA  - Jan 22
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1362361320985680
DP  - Ovid Technologies
J2  - Autism
L1  - internal-pdf://2163587051/Rodgers-2021-Intensive behavioural interventio.pdf
LA  - English
N1  - Rodgers, MarkSimmonds, MarkMarshall, DavidHodgson, RobertStewart, Lesley ARai, DheerajWright, KathBen-Itzchak, EstherEikeseth, SveinEldevik, SigmundKovshoff, HannaMagiati, IlianaOsborne, Lisa AReed, PhilVivanti, GiacomoZachor, DitzaCouteur, Ann Le
PY  - 2021
SP  - 1362361320985680
T2  - Autism
TI  - Intensive behavioural interventions based on applied behaviour analysis for young children with autism: An international collaborative individual participant data meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33482692
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33482692&amp;id=doi:10.1177%2F1362361320985680&amp;issn=1362-3613&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1362361320985680&amp;pages=1362361320985680&amp;date=2021&amp;title=Autism&amp;atitle=Intensive+behavioural+interventions+based+on+applied+behaviour+analysis+for+young+children+with+autism%3A+An+international+collaborative+individual+participant+data+meta-analysis.&amp;aulast=Rodgers&amp;pid=%3Cauthor%3ERodgers+M%3C%2Fauthor%3E%3CAN%3E33482692%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1362361320985680
ER  -
TY  - JOUR
AB  - **Background** Physical fitness is an important marker of current and future health status, yet the association between physical fitness and indicators of mental health in youth has not been systematically reviewed and meta-analyzed. 

**Objective** The aim of this work was to systematically review and meta-analyze the association between physical fitness components (i.e. cardiorespiratory fitness, muscular fitness, speed-agility, flexibility and fitness composite) and mental health indicators (i.e. psychological well-being and psychological ill-being) in preschoolers, children and adolescents. Design Systematic review and meta-analysis. 

**Data Sources** Systematic searches were conducted in PubMed, Web of Science and Scopus from database inception to May 2020. Eligibility Criteria Studies (cross-sectional, longitudinal and intervention designs) were included if they measured at least one physical fitness component and one mental health indicator in healthy youth (2-18 years). Results A total of 58 unique studies (52 cross-sectional, 4 longitudinal and 4 intervention studies) met all eligibility criteria and were included. There was a significant positive overall association between physical fitness and mental health in children and adolescents (pooled r = 0.206, p &lt; 0.001). We found suggestive evidence of moderation by age group, fitness components and socioeconomic status (all p &lt; 0.08). No relevant studies focusing on preschoolers were identified. Evidence based on longitudinal and intervention studies was limited. Conclusion We observed a small to medium sized positive association between physical fitness and overall mental health in youth. However, as the majority of studies were cross-sectional, additional longitudinal and intervention studies are needed to provide evidence of causation.
AN  - WOS:000677946300001
AU  - Cadenas-Sanchez,
AU  - C.
AU  - Mena-Molina,
AU  - A.
AU  - Torres-Lopez,
AU  - L.
AU  - V.
AU  - Migueles,
AU  - J.
AU  - H.
AU  - Rodriguez-Ayllon,
AU  - M.
AU  - Lubans,
AU  - D.
AU  - R.
AU  - Ortega,
AU  - F.
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40279-021-01520-y
L1  - internal-pdf://3017501227/Cadenas-Sanchez-Healthier Minds in Fitter Bodi.pdf
PY  - 2021
SP  - 35
T2  - Sports Medicine
TI  - Healthier Minds in Fitter Bodies: A Systematic Review and Meta-Analysis of the Association between Physical Fitness and Mental Health in Youth
UR  - &lt;Go to ISI&gt;://WOS:000677946300001
UR  - https://link.springer.com/content/pdf/10.1007/s40279-021-01520-y.pdf
ER  -
TY  - JOUR
AB  - **Background**
Preterm infants require high protein intake to achieve adequate growth and development. Although breast milk feeding has many benefits for this population, the protein content is highly variable, and inadequate to support rapid infant growth. This is a 2020 update of a Cochrane Review first published in 1999.

**Objectives**
To determine whether protein‐supplemented human milk compared with unsupplemented human milk, fed to preterm infants, improves growth, body composition, cardio‐metabolic, and neurodevelopmental outcomes, without significant adverse effects.

**Search methods**
We used the standard search strategy of Cochrane Neonatal to search Cochrane Central Register of Controlled Trials (CENTRAL 2019, Issue 8) in the Cochrane Library and MEDLINE via PubMed on 23 August 2019. We also searched clinical trials databases and the reference lists of retrieved articles for randomised controlled trials and quasi‐randomised trials.

**Selection criteria**
Published and unpublished RCTs were eligible if they used random or quasi‐random methods to allocate hospitalised preterm infants who were being fed human milk, to additional protein supplementation or no supplementation.

**Data collection and analysis**
Two review authors independently abstracted data, assessed risk of bias and the quality of evidence at the outcome level, using GRADE methodology. We performed meta‐analyses, using risk ratio (RR) for dichotomous data, and mean difference (MD) for continuous data, with their respective 95% confidence intervals (CIs). We used a fixed‐effect model and had planned to explore potential causes of heterogeneity via subgroup or sensitivity analyses.

**Main results**
We included six RCTs, involving 204 preterm infants. The risk of bias for most methodological domains was unclear as there was insufficient detail reported. Low‐quality evidence showed that protein supplementation of human milk may increase in‐hospital rates of growth in weight (MD 3.82 g/kg/day, 95% CI 2.94 to 4.7; five RCTs, 101 infants; I&sup2; = 73%), length (MD 0.12 cm/wk, 95% CI 0.07 to 0.17; four RCTs, 68 infants; I&sup2; = 89%), and head circumference (MD 0.06 cm/wk, 95% CI 0.01 to 0.12; four RCTs, 68 infants; I&sup2; = 84%). Protein supplementation may lead to longer hospital stays (MD 18.5 days, 95% CI 4.39 to 32.61; one RCT, 20 infants; very low‐quality evidence). Very low quality evidence means that the effect of protein supplementation on the risk of feeding intolerance (RR 2.70, 95% CI 0.13 to 58.24; one RCT, 17 infants), or necrotizing enterocolitis (RR 1.11, 95% CI 0.07 to 17.12; one RCT, 76 infants) remains uncertain. No data were available about the effects of protein supplementation on neurodevelopmental outcomes.

**Authors&#039; conclusions**
Low‐quality evidence showed that protein supplementation of human milk, fed to preterm infants, increased short‐term growth. However, the small sample sizes, low precision, and very low‐quality evidence regarding duration of hospital stay, feeding intolerance, and necrotising enterocolitis precluded any conclusions about these outcomes. There were no data on outcomes after hospital discharge. Our findings may not be generalisable to low‐resource settings, as none of the included studies were conducted in these settings.Since protein supplementation of human milk is now usually done as a component of multi‐nutrient fortifiers, future studies should compare different amounts of protein in multi‐component fortifiers, and be designed to determine the effects on duration of hospital stay and safety, as well as on long‐term growth, body composition, cardio‐metabolic, and neurodevelopmental outcomes.
AU  - Amissah,
AU  - E.
AU  - Brown,
AU  - J.
AU  - Harding,
AU  - J.
AU  - E.
DA  - September
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD000433.pub3
L1  - internal-pdf://4023313078/Amissah_et_al-2020-Cochrane_Database_of_System.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Protein supplementation of human milk for promoting growth in preterm infants
ER  -
TY  - JOUR
AB  - **Background:** 
The objective of this systematic review was to examine the treatment effects of exercise on children and adolescents with depression compared to either other nonexercise treatments or no treatment. A study protocol was registered in PROSPERO (CRD42018101982). 

**Method(s):** 
Cochrane Central Register of Controlled Trials (CENTRAL), Medline (Ovid), Embase (Ovid), PsycINFO (Ovid), AMED (Ovid), SPORTDiscus, PEDro, CINAHL (EBSCO), ERIC (EBSCO), Web of Science, and databases for grey literature and dissertations were searched from their inception through 30 August 2020 for randomized controlled trials. Varieties of search terms for depression, children and adolescents, exercise, and study design were applied. No limits were placed on publication year, language or publication type. Registers for ongoing trials were also searched. Two authors independently screened references, extracted data and assessed risk of bias in the included trials. The effect sizes for depression postintervention were pooled in a meta-analysis, and the certainty of the evidence was assessed using GRADE (Grading of Recommendations Assessments, Development, and Evaluation). 

**Result(s):** 
13,307 references were screened. Four trials were included (n = 159). Participants were between 12 and 18 years old, and predominantly female. A meta-analysis with a random-effects model was performed, and a moderate effect in favour of exercise on postintervention depression severity was identified (SMD = -0.59, 95% CI = -1.08 to -0.10, p =.02). However, the overall certainty of the evidence for this outcome was low. One trial found a nonsignificant decrease in depression severity at six-month follow-up (n = 42, SMD = -0.59, 95% CI = -1.22 to 0.04, p = 0.07), and the overall certainty of the evidence for this outcome was very low. One trial found no statistically significant differences between the exercise and control groups on quality of life. Other outcomes, including adverse events, psychological well-being and social functioning, were not evaluated. 

**Conclusion(s):** 
Low certainty evidence suggests that exercise interventions may be associated with a decrease in adolescent depression severity. However, our confidence in the effect estimate is limited, and the true effect may be substantially different. Thus, large, high-quality trials including follow-up periods are needed. Copyright &copy; 2020 Association for Child and Adolescent Mental Health
AD  - (Axelsdottir, Biedilae, Sagatun) Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway (Axelsdottir, Biedilae, Nordheim) Department of Health and Functioning, Western Norway University of Applied Sciences, Bergen, Norway (Larun) Division of Health Services, Norwegian Institute of Public Health, Oslo, NorwayB. Axelsdottir, Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway. E-mail: ba@r-bup.no S. Biedilae, Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway. E-mail: sb@r-bup.no B. Axelsdottir, Department of Health and Functioning, Western Norway University of Applied Sciences, Bergen, Norway. E-mail: ba@r-bup.no S. Biedilae, Department of Health and Functioning, Western Norway University of Applied Sciences, Bergen, Norway. E-mail: sb@r-bup.no
AN  - 2007508999
AU  - Axelsdottir,
AU  - B.
AU  - Biedilae,
AU  - S.
AU  - Sagatun,
AU  - A.
AU  - Nordheim,
AU  - L.
AU  - V.
AU  - Larun,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/camh.12438
DP  - Ovid Technologies
KW  - adolescent
KW  - child
KW  - Depressive disorder
KW  - exercise
KW  - meta-analysis
KW  - systematic review
KW  - adolescent depression
KW  - adult
KW  - Cinahl
KW  - Cochrane Library
KW  - effect size
KW  - Embase
KW  - female
KW  - follow up
KW  - grey literature
KW  - human
KW  - language
KW  - Medline
KW  - meta analysis
KW  - PEDro
KW  - psychological well-being
KW  - PsycINFO
KW  - quality of life
KW  - randomized controlled trial (topic)
KW  - review
KW  - risk assessment
KW  - social interaction
KW  - Web of Science
L1  - internal-pdf://3934907000/Axelsdottir-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - Child and Adolescent Mental Health.
TI  - Review: Exercise for depression in children and adolescents - a systematic review and meta-analysis
UR  - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1475-3588
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2007508999
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33277972&amp;id=doi:10.1111%2Fcamh.12438&amp;issn=1475-357X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Child+and+Adolescent+Mental+Health&amp;atitle=Review%3A+Exercise+for+depression+in+children+and+adolescents+-+a+systematic+review+and+meta-analysis&amp;aulast=Axelsdottir&amp;pid=%3Cauthor%3EAxelsdottir+B.%3C%2Fauthor%3E%3CAN%3E2007508999%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://acamh.onlinelibrary.wiley.com/doi/10.1111/camh.12438
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/camh.12438?download=true
ER  -
TY  - JOUR
AB  - **Background**
Preterm infants are born with low glycogen stores and require higher glucose intake to match fetal accretion rates. In spite of the myriad benefits of breast milk for preterm infants, it may not adequately meet the needs of these rapidly growing infants. Supplementing human milk with carbohydrates may help. However, there is a paucity of data on assessment of benefits or harms of carbohydrate supplementation of human milk to promote growth in preterm infants. This is a 2020 update of a Cochrane Review first published in 1999.

**Objectives**
To determine whether human milk supplemented with carbohydrate compared with unsupplemented human milk fed to preterm infants improves growth, body composition, and cardio‐metabolic and neurodevelopmental outcomes without significant adverse effects.

**Search methods**
We used the standard search strategy of Cochrane Neonatal to search Cochrane Central Register of Controlled Trials (CENTRAL 2019, Issue 8) in the Cochrane Library and MEDLINE via PubMed on 22 August 2019. We also searched clinical trials databases and the reference lists of retrieved articles for randomised controlled trials and quasi‐randomised trials.

**Selection criteria**
Published and unpublished controlled trials were eligible if they used random or quasi‐random methods to allocate preterm infants in hospital fed human milk to supplementation or no supplementation with additional carbohydrate.

**Data collection and analysis**
Two review authors independently abstracted data and assessed trial quality and the quality of evidence at the outcome level using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) method. We planned to perform meta‐analyses using risk ratios (RRs) for dichotomous data and mean differences (MDs) for continuous data, with their respective 95% confidence intervals (CIs). We planned to use a fixed‐effect model and to explore potential causes of heterogeneity via sensitivity analyses. We contacted study authors for additional information.

**Main results**
One unblinded, quasi‐randomised controlled trial (RCT) assessing effects of carbohydrate supplementation of human milk in the form of a prebiotic in 75 preterm infants was eligible for inclusion in this review. We identified two publications of the same trial, which reported different methods regarding blinding and randomisation. Study authors confirmed that these publications pertain to the same trial, but they have not yet clarified which method is correct. We were unable to reproduce analyses from the data presented. At 30 days of age, the mean weight of preterm infants in the trial was greater in the prebiotic carbohydrate‐supplemented group than in the unsupplemented group (MD 160.4 grams, 95% CI 12.4 to 308.4 grams; one RCT, N = 75; very low‐quality evidence). We found no evidence of a clear difference in risk of feeding intolerance (RR 0.64, 95% CI 0.36 to 1.15; one RCT, N = 75 infants; very low‐quality evidence) or necrotising enterocolitis (NEC) (RR 0.2, 95% CI 0.02 to 1.3; one RCT, N = 75 infants; very low‐quality evidence) between the prebiotic‐supplemented group and the unsupplemented group. Duration of hospital stay was shorter in the prebiotic group than in the control group at a median (range) of 16 (9 to 45) days (95% CI 15.34 to 24.09) and 25 (11 to 80) days (95% CI 25.52 to 34.39), respectively. No other data were available for assessing effects of carbohydrate supplementation on short‐ and long‐term growth, body mass index, body composition, and neurodevelopmental or cardio‐metabolic outcomes.

**Authors&#039; conclusions**
We found insufficient evidence on the short‐ and long‐term effects of carbohydrate supplementation of human milk in preterm infants. The only trial included in this review presented very low‐quality evidence, and study authors provided uncertain information about study methods and analysis. The evidence may be limited in its applicability because researchers included a small sample of preterm infants from a single centre. However, the outcomes assessed are common to all preterm infants, and this trial demonstrates the feasibility of prebiotic carbohydrate supplementation in upper‐middle‐income countries. Future trials should assess the safety and efficacy of different types and concentrations of carbohydrate supplementation for preterm infants fed human milk. Although prebiotic carbohydrate supplementation in preterm infants is currently a topic of active research, we do not envisage that further trials of digestible carbohydrates will be conducted, as this is currently done as a component of multi‐nutrient human milk fortification. Hence we do not plan to publish any further updates of this review.
AU  - Amissah,
AU  - E.
AU  - A.
AU  - Brown,
AU  - J.
AU  - Harding,
AU  - J.
AU  - E.
DA  - September
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD000280.pub3
L1  - internal-pdf://1305705467/Amissah_et_al-2020-Cochrane_Database_of_System.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Carbohydrate supplementation of human milk to promote growth in preterm infants
ER  -
TY  - JOUR
AB  - Current research has reported the beneficial effects of mindfulness-based interventions (MBIs) on general domains of cognition and behavior among children. The present study is the first meta-analysis with controlled studies investigating the pre-post change effects of MBIs on two widely experienced behaviors in childhood education, namely inattentiveness and hyperactivity-impulsivity. With a special developmental focus on the early years, a total of 21 studies with 3- to 12-year-old children were included in the meta-analysis. Results indicated that MBIs decreased children&#039;s overall inattentive and hyperactive-impulsive behavior with a small but significant effect size (k = 21, g&lt;sup&gt;+&lt;/sup&gt; =.38, p &lt;.001). However, this overall positive effect was only significant when teachers rated children&#039;s behavior and nonsignificant when parents and children themselves were the informants. Additionally, MBIs showed a moderate effect in reducing inattentiveness and hyperactivity-impulsivity for children at risk for such behavior. In conclusion, results indicate that MBIs, which are relatively easily applied in educational practice, have the potential to decrease inattentive and hyperactive-impulsive behavior and might contribute to children&#039;s overall better functioning at school. Copyright &copy; The Author(s) 2020.
AD  - (Vekety) ELTE Eotvos Lorand University, Hungary (Vekety, Takacs) MTA-ELTE Lendulet Adaptation Research Group, Hungary (Logemann) Institute of Psychology, ELTE Eotvos Lorand University, Hungary (Takacs) Institute of Education, ELTE Eotvos Lorand University, HungaryZ.K. Takacs, MTA-ELTE Lendulet Adaptation Research Group, Hungary. E-mail: takacs.zsofia@ppk.elte.hu Z.K. Takacs, Institute of Education, ELTE Eotvos Lorand University, Hungary. E-mail: takacs.zsofia@ppk.elte.hu
AN  - 2006924907
AU  - Vekety,
AU  - B.
AU  - Logemann,
AU  - H.
AU  - N.
AU  - A.
AU  - Takacs,
AU  - Z.
AU  - K.
DA  - nov 23
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/0165025420958192
DP  - Ovid Technologies
KW  - adhd
KW  - children
KW  - hyperactivity
KW  - impulsivity
KW  - inattention
KW  - Inattentiveness
KW  - meta-analysis
KW  - mindfulness
KW  - mindfulness-based interventions
KW  - article
KW  - attention deficit disorder
KW  - child
KW  - child behavior
KW  - childhood
KW  - cognition
KW  - controlled study
KW  - education
KW  - effect size
KW  - female
KW  - human
KW  - human experiment
KW  - impulsiveness
KW  - male
KW  - meta analysis
KW  - systematic review
KW  - teacher
L1  - internal-pdf://1809443672/Vekety-2020-The effect of mindfulness-based in.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - International Journal of Behavioral Development.
TI  - The effect of mindfulness-based interventions on inattentive and hyperactive-impulsive behavior in childhood: A meta-analysis
UR  - http://jbd.sagepub.com/archive/
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2006924907
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1177%2F0165025420958192&amp;issn=0165-0254&amp;isbn=&amp;volume=&amp;issue=&amp;spage=0165025420&amp;pages=&amp;date=2020&amp;title=International+Journal+of+Behavioral+Development&amp;atitle=The+effect+of+mindfulness-based+interventions+on+inattentive+and+hyperactive-impulsive+behavior+in+childhood%3A+A+meta-analysis&amp;aulast=Vekety&amp;pid=%3Cauthor%3EVekety+B.%3C%2Fauthor%3E%3CAN%3E2006924907%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0165025420958192
ER  -
TY  - JOUR
AB  - **Background**
Bipolar disorder is one of the most common serious mental illnesses, affecting approximately 60 million people worldwide. Characterised by extreme alterations in mood, cognition, and behaviour, bipolar disorder can have a significant negative impact on the functioning and quality of life of the affected individual. Compared with the general population, the prevalence of comorbid obesity is significantly higher in bipolar disorder. Approximately 68% of treatment seeking bipolar patients are overweight or obese. Clinicians are aware that obesity has the potential to contribute to other physical health conditions in people with bipolar disorder, including diabetes, hypertension, metabolic syndrome, cardiovascular disease, and coronary heart disease. Cardiovascular disease is the leading cause of premature death in bipolar disorder, happening a decade or more earlier than in the general population. Contributing factors include illness‐related factors (mood‐related factors, i.e. mania or depression), treatment‐related factors (weight implications and other side effects of medications), and lifestyle factors (physical inactivity, poor diet, smoking, substance abuse). Approaches to the management of obesity in individuals with bipolar disorder are diverse and include non‐pharmacological interventions (i.e. dietary, exercise, behavioural, or multi‐component), pharmacological interventions (i.e. weight loss drugs or medication switching), and bariatric surgery.

**Objectives**
To assess the effectiveness of interventions for the management of obesity in people with bipolar disorder.

**Search methods**
We searched the Cochrane Common Mental Disorders Controlled Trials Register (CCMDCTR) and the Cochrane Central Register for Controlled Trials (CENTRAL) to February 2019. We ran additional searches via Ovid databases including MEDLINE, Embase, and PsycInfo to May 2020. We searched the World Health Organization (WHO) trials portal (International Clinical Trials Registry Platform (ICTRP)) and ClinicalTrials.gov. We also checked the reference lists of all papers brought to full‐text stage and all relevant systematic reviews.

**Selection criteria**
Randomised controlled trials (RCTs), randomised at the level of the individual or cluster, and cross‐over designs of interventions for management of obesity, in which at least 80% of study participants had a clinical diagnosis of bipolar disorder and comorbid obesity (body mass index (BMI) &ge; 30 kg/m&sup2;), were eligible for inclusion. No exclusions were based on type of bipolar disorder, stage of illness, age, or gender. We included non‐pharmacological interventions comprising dietary, exercise, behavioural, and multi‐component interventions; pharmacological interventions consisting of weight loss medications and medication switching interventions; and surgical interventions such as gastric bypass, gastric bands, biliopancreatic diversion, and vertical banded gastroplasty. Comparators included the following approaches: dietary intervention versus inactive comparator; exercise intervention versus inactive comparator; behavioural intervention versus inactive comparator; multi‐component lifestyle intervention versus inactive comparator; medication switching intervention versus inactive comparator; weight loss medication intervention versus inactive comparator; and surgical intervention versus inactive comparator. Primary outcomes of interest were changes in body mass, patient‐reported adverse events, and quality of life.

**Data collection and analysis**
Four review authors were involved in the process of selecting studies. Two review authors independently screened the titles and abstracts of studies identified in the search. Studies brought to the full‐text stage were then screened by another two review authors working independently. However, none of the full‐text studies met the inclusion criteria. Had we included studies, we would have assessed their methodological quality by using the criteria recommended in the Cochrane Handbook for Systematic Reviews of Interventions. We intended to combine dichotomous data using risk ratios (RRs), and continuous data using mean differences (MDs). For each outcome, we intended to calculate overall effect size with 95% confidence intervals (CIs).

**Main results**
None of the studies that were screened met the inclusion criteria.

**Authors&#039; conclusions**
None of the studies that were assessed met the inclusion criteria of this review. Therefore we were unable to determine the effectiveness of interventions for the management of obesity in individuals with bipolar disorder. Given the extent and impact of the problem and the absence of evidence, this review highlights the need for research in this area. We suggest the need for RCTs that will focus only on populations with bipolar disorder and comorbid obesity. We identified several ongoing studies that may be included in the update of this review.
AU  - Tully,
AU  - A.
AU  - Smyth,
AU  - S.
AU  - Conway,
AU  - Y.
AU  - Geddes,
AU  - J.
AU  - Devane,
AU  - D.
AU  - Kelly,
AU  - JP.
AU  - Jordan,
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD013006.pub2
L1  - internal-pdf://0444791408/Tully_et_al-2020-Cochrane_Database_of_Systemat.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for the management of obesity in people with bipolar disorder
ER  -
TY  - JOUR
AB  - **Objective:** 
Peer social functioning difficulties characteristic of ADHD persist into adolescence, but the efficacy of interventions for this age group remains unclear. 

**Method:** 
A systematic search of nonpharmacological interventions for adolescents with ADHD (10&ndash;18 years) identified 11 trials addressing social functioning, of which eight were included in meta-analyses. 

**Results:** 
Random effects meta-analyses of four randomized trials found no differences in social functioning between treatment and control groups by parent- (g = &minus;0.08 [&minus;0.34, 0.19], k = 4, N = 354) or teacher-report (g = 0.17 [&minus;0.06, 0.40], k = 3, N = 301). Meta-analyses of nonrandomized studies indicated participants&rsquo; social functioning improved from baseline to postintervention by parent-report, but not teacher- or self-report. All trials had a high risk of bias. 

**Conclusion:** 
These results highlight the paucity of research in this age group. There is little evidence that current interventions improve peer social functioning. Clearer conceptualizations of developmentally relevant targets for remediation may yield more efficacious social interventions.
AD  - Morris, Sarah. Deakin University, School of Psychology, Geelong, Victoria, Australia.Sheen, Jade. Deakin University, School of Psychology, Geelong, Victoria, Australia.Ling, Mathew. Deakin University, School of Psychology, Geelong, Victoria, Australia.Foley, Denise. Deakin University, School of Psychology, Geelong, Victoria, Australia.Sciberras, Emma. Deakin University, School of Psychology, Geelong, Victoria, Australia.Sciberras, Emma. Murdoch Children&#039;s Research Institute, Parkville, Victoria, Australia.Sciberras, Emma. University of Melbourne, Department of Paediatrics, Parkville, Victoria, Australia.
AN  - 32131667
AU  - Morris,
AU  - S.
AU  - Sheen,
AU  - J.
AU  - Ling,
AU  - M.
AU  - Foley,
AU  - D.
AU  - Sciberras,
AU  - E.
DA  - Mar 05
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1087054720906514
DP  - Ovid Technologies
J2  - J Atten Disord
L1  - internal-pdf://0598022427/Morris-2020-Interventions for Adolescents With.pdf
LA  - English
N1  - Morris, SarahSheen, JadeLing, MathewFoley, DeniseSciberras, Emma
PY  - 2020
SP  - 1087054720906514
T2  - Journal of Attention Disorders
TI  - Interventions for Adolescents With ADHD to Improve Peer Social Functioning: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32131667
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32131667&amp;id=doi:10.1177%2F1087054720906514&amp;issn=1087-0547&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1087054720906514&amp;pages=1087054720906514&amp;date=2020&amp;title=Journal+of+Attention+Disorders&amp;atitle=Interventions+for+Adolescents+With+ADHD+to+Improve+Peer+Social+Functioning%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Morris&amp;pid=%3Cauthor%3EMorris+S%3C%2Fauthor%3E%3CAN%3E32131667%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1087054720906514
ER  -
TY  - JOUR
AB  - **Objective**: he goal of this work was to perform a systematic review and meta-analysis evaluating and comparing exercise related improvements in various executive function (EF) domains among children and adolescents with attention-deficit hyperactivity disorder (ADHD), Autism Spectrum Disorders (ASD), and Fetal Alcohol Spectrum Disorders (FASD). 

**Method(s)**: A systematic literature research was conducted in PubMed, CENTRAL, and PsycInfo from October 1st, 2018 through January 30th, 2019 for original peer-reviewed articles investigating the relationship between exercise interventions and improvements in three domains of executive function (working memory, attention/set shifting, and response inhibition) among children and adolescents with ADHD, ASD, and FASD. Effect sizes (ES) were extracted and combined with random-effects meta-analytic methods. Covariates and moderators were then analyzed using meta-regression and subgroup analyses. 

**Result(s)**: A total of 28 studies met inclusion criteria, containing information on 1,281 youth (N=1197 ADHD, N= 54 ASD, N=30 FASD). For ADHD, exercise interventions were associated with moderate improvements in attention/set-shifting (ES 0.38, 95% CI 0.01-0.75, k=14) and approached significance for working memory (ES 0.35, 95%CI-0.17-0.88, k=5) and response inhibition (ES 0.39, 95%CI-0.02-0.80, k=12). For ASD and FASD, exercise interventions were associated with large improvements in working memory (ES 1.36, 95%CI 1.08-1.64) and response inhibition (ES 0.78, 95%CI 0.21-1.35) and approached significance for attention/set-shifting (ES 0.69, 95%-0.28-1.66). There was evidence of substantial methodologic and substantive heterogeneity among studies. Sample size, mean age, study design, and the number or duration of intervention sessions did not significantly moderate the relationship between exercise and executive function. 

**Conclusion(s)**: Exercise interventions among children and adolescents with neurodevelopmental disorders were associated with moderate improvements in executive function domains. Of note, studies of youth with ASD and FASD tended to report higher effect sizes compared to studies of youth with ADHD, albeit few existing studies. Exercise may be a potentially cost-effective and readily implementable intervention to improve executive function in these populations. Copyright &copy; 2020, UNIV SAOPAULO. All rights reserved.
AD  - (Varigonda, Edgcomb, Zima) University of California Los Angeles - Psychiatry, Los Angeles, CA, United StatesA.L. Varigonda, University of California Los Angeles - Psychiatry, 760 Westwood Plaza, Los Angeles, CA 90095, United States. E-mail: avarigonda@caps.ucla.edu
AN  - 2006801150
AU  - Varigonda,
AU  - A.
AU  - L.
AU  - Edgcomb,
AU  - J.
AU  - B.
AU  - Zima,
AU  - B.
AU  - T.
DA  - September-October
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1590/0101-60830000000251
DP  - Ovid Technologies
KW  - Anxiety
KW  - Depression
KW  - Epidemiology
KW  - mini
KW  - Prisoners
KW  - adolescent
KW  - analytic method
KW  - article
KW  - attention deficit disorder
KW  - autism
KW  - child
KW  - controlled study
KW  - effect size
KW  - executive function
KW  - exercise
KW  - fetal alcohol syndrome
KW  - human
KW  - juvenile
KW  - male
KW  - Medline
KW  - meta analysis
KW  - prisoner
KW  - PsycINFO
KW  - sample size
KW  - systematic review
KW  - working memory
L1  - internal-pdf://2728273594/Varigonda-2020.pdf
LA  - English
PY  - 2020
SP  - 146-156
T2  - Revista de Psiquiatria Clinica
TI  - The impact of exercise in improving executive function impairments among children and adolescents with adhd, autism spectrum disorder, and fetal alcohol spectrum disorder: A systematic review and meta-analysis
UR  - http://www.scielo.br/pdf/rpc/v47n5/1806-938X-rpc-47-05-0146.pdf
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2006801150
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1590%2F0101-60830000000251&amp;issn=0101-6083&amp;isbn=&amp;volume=47&amp;issue=5&amp;spage=146&amp;pages=146-156&amp;date=2020&amp;title=Revista+de+Psiquiatria+Clinica&amp;atitle=The+impact+of+exercise+in+improving+executive+function+impairments+among+children+and+adolescents+with+adhd%2C+autism+spectrum+disorder%2C+and+fetal+alcohol+spectrum+disorder%3A+A+systematic+review+and+meta-analysis&amp;aulast=Varigonda&amp;pid=%3Cauthor%3EVarigonda+A.L.%3C%2Fauthor%3E%3CAN%3E2006801150%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
VL  - 47
ER  -
TY  - JOUR
AB  - This article reports a systematic review of the effectiveness of individual child play therapy with children aged 4-12 on several different presenting concerns. From over 5,000 citations, 180 studies were reviewed in detail and 17 met the inclusion criteria. A wide range of results on different concerns were revealed, with effect sizes ranging fromd= -0.04 tog= 3.63, though most ranged from .35 to .80. Across most concerns, play therapy was affirmed as an empirically supported therapy.
AN  - WOS:000556260400003
AU  - Drisko,
AU  - J.
AU  - Corvino,
AU  - P.
AU  - Kelly,
AU  - L.
AU  - Nielson,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/1049731519854157
L1  - internal-pdf://3547028397/Drisko-2020.pdf
N1  - Drisko, James Corvino, Perri Kelly, Lisa Nielson, Jane1552-7581
PY  - 2020
SP  - 715-723
T2  - Research on Social Work Practice
TI  - Is Individual Child Play Therapy Effective?
UR  - &lt;Go to ISI&gt;://WOS:000556260400003
UR  - https://journals.sagepub.com/doi/10.1177/1049731519854157
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1049731519854157
VL  - 30
ER  -
TY  - JOUR
AB  - Although the technological revolution of recent decades has produced undeniable advances, it has also generated problems derived from new forms of human communication, especially among the younger population. This is the case with cyber dating violence, a problem that affects between 12% and 56% of young couples, making the need for preventive intervention patently evident. This study attempts to fill a gap in the literature in this field, carrying out a systematic review of universal cyber dating violence prevention programs, analyzing their characteristics and the evidence provided of their effectiveness. Following the PRISMA method, only 3 programs met the inclusion criteria: the DARSI program, the Dat-e Adolescence program and the Brief Incremental Theory of Personality (ITP) adolescent dating violence prevention program. All were reported to be effective, based on different indicators. Given the small body of work published to date and the limitations of the aforementioned programs, future research should aim to design and validate a greater number of programs that serve as tools for addressing this problem in a timely manner, in order to avoid not only the serious consequences it has for victims, but also its escalation towards adulthood.
AN  - WOS:000596534200001
AU  - Galende,
AU  - N.
AU  - Ozamiz-Etxebarria,
AU  - N.
AU  - Jaureguizar,
AU  - J.
AU  - Redondo,
AU  - I.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2147/PRBM.S275414
L1  - internal-pdf://2555519159/Galende-2020.pdf
PY  - 2020
SP  - 1089-1099
T2  - PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
TI  - Cyber Dating Violence Prevention Programs in Universal Populations: A Systematic Review
UR  - https://www.dovepress.com/getfile.php?fileID=64242
VL  - 13
ER  -
TY  - JOUR
AB  - BACKGROUND: Depressive disorders are common in children and adolescents. Antidepressants, psychotherapies, and their combination are often used in routine clinical practice; however, available evidence on the comparative efficacy and safety of these interventions is inconclusive. Therefore, we sought to compare and rank all available treatment interventions for the acute treatment of depressive disorders in children and adolescents.

METHODS: We did a systematic review and network meta-analysis. We searched PubMed, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, PsycINFO, ProQuest, CINAHL, LiLACS, international trial registries, and the websites of regulatory agencies for published and unpublished randomised controlled trials from database inception until Jan 1, 2019. We included placebo-controlled and head-to-head trials of 16 antidepressants, seven psychotherapies, and five combinations of antidepressant and psychotherapy that are used for the acute treatment of children and adolescents (&lt;=18 years old and of both sexes) with depressive disorder diagnosed according to standard operationalised criteria. Trials recruiting participants with treatment-resistant depression, bipolar disorder, psychotic depression, treatment duration of less than 4 weeks, or an overall sample size of fewer than ten patients were excluded. We extracted data following a predefined hierarchy of outcome measures, and assessed risk of bias and certainty of evidence using validated methods. Primary outcomes were efficacy (change in depressive symptoms) and acceptability (treatment discontinuation due to any cause). We estimated summary standardised mean differences (SMDs) or odds ratios (ORs) with credible intervals (CrIs) using network meta-analysis with random effects. This study was registered with PROSPERO, number CRD42015020841.

FINDINGS: From 20 366 publications, we included 71 trials (9510 participants). Depressive disorders in most studies were moderate to severe. In terms of efficacy, fluoxetine plus cognitive behavioural therapy (CBT) was more effective than CBT alone (-0.78, 95% CrI -1.55 to -0.01) and psychodynamic therapy (-1.14, -2.20 to -0.08), but not more effective than fluoxetine alone (-0.22, -0.86 to 0.42). No pharmacotherapy alone was more effective than psychotherapy alone. Only fluoxetine plus CBT and fluoxetine were significantly more effective than pill placebo or psychological controls (SMDs ranged from -1.73 to -0.51); and only interpersonal therapy was more effective than all psychological controls (-1.37 to -0.66). Nortriptyline (SMDs ranged from 1.04 to 2.22) and waiting list (SMDs ranged from 0.67 to 2.08) were less effective than most active interventions. In terms of acceptability, nefazodone and fluoxetine were associated with fewer dropouts than sertraline, imipramine, and desipramine (ORs ranged from 0.17 to 0.50); imipramine was associated with more dropouts than pill placebo, desvenlafaxine, fluoxetine plus CBT, and vilazodone (2.51 to 5.06). Most of the results were rated as &quot;low&quot; to &quot;very low&quot; in terms of confidence of evidence according to Confidence In Network Meta-Analysis.

INTERPRETATION: Despite the scarcity of high-quality evidence, fluoxetine (alone or in combination with CBT) seems to be the best choice for the acute treatment of moderate-to-severe depressive disorder in children and adolescents. However, the effects of these interventions might vary between individuals, so patients, carers, and clinicians should carefully balance the risk-benefit profile of efficacy, acceptability, and suicide risk of all active interventions in young patients with depression on a case-by-case basis.

FUNDING: National Key Research and Development Program of China.
AD  - Zhou, Xinyu. Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Teng, Teng. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Zhang, Yuqing. Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.Del Giovane, Cinzia. Institute of Primary Health Care, University of Bern, Bern, Switzerland.Furukawa, Toshi A. Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine and School of Public Health, Kyoto, Japan.Weisz, John R. Department of Psychology, Harvard University, Cambridge, MA, USA.Li, Xuemei. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Cuijpers, Pim. Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.Coghill, David. Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia.Xiang, Yajie. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Hetrick, Sarah E. Department of Psychological Medicine, University of Auckland, Auckland, New Zealand.Leucht, Stefan. Department of Psychiatry and Psychotherapy, School of Medicine, Technische Universitat Munchen, Munich, Germany.Qin, Mengchang. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Barth, Jurgen. Institute for Complementary and Integrative Medicine, University Hospital Zurich and University of Zurich, Zurich, Switzerland.Ravindran, Arun V. Department of Psychiatry, University of Toronto and Division of Mood and Anxiety Disorders, Centre for Addiction and Mental Health, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.Yang, Lining. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Curry, John. Department of Psychiatry &amp; Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA.Fan, Li. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Silva, Susan G. Duke University School of Nursing, Durham, NC, USA.Cipriani, Andrea. Department of Psychiatry, University of Oxford, Oxford, UK; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.Xie, Peng. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: xiepeng973@126.com.
AN  - 32563306
AU  - Zhou,
AU  - X.
AU  - Teng,
AU  - T.
AU  - Zhang,
AU  - Y.
AU  - Del
AU  - Giovane,
AU  - C.
AU  - Furukawa,
AU  - T.
AU  - A.
AU  - Weisz,
AU  - J.
AU  - R.
AU  - Li,
AU  - X.
AU  - Cuijpers,
AU  - P.
AU  - Coghill,
AU  - D.
AU  - Xiang,
AU  - Y.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Leucht,
AU  - S.
AU  - Qin,
AU  - M.
AU  - Barth,
AU  - J.
AU  - Ravindran,
AU  - A.
AU  - V.
AU  - Yang,
AU  - L.
AU  - Curry,
AU  - J.
AU  - Fan,
AU  - L.
AU  - Silva,
AU  - S.
AU  - G.
AU  - Cipriani,
AU  - A.
AU  - Xie,
AU  - P.
DA  - Jul
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/S2215-0366(20)30137-1
DP  - Ovid Technologies
J2  - Lancet Psychiatry
L1  - internal-pdf://3022368914/Zhou-2020-Comparative efficacy and acceptabili.pdf
LA  - English
N1  - Zhou, XinyuTeng, TengZhang, YuqingDel Giovane, CinziaFurukawa, Toshi AWeisz, John RLi, XuemeiCuijpers, PimCoghill, DavidXiang, YajieHetrick, Sarah ELeucht, StefanQin, MengchangBarth, JurgenRavindran, Arun VYang, LiningCurry, JohnFan, LiSilva, Susan GCipriani, AndreaXie, PengS2215-0366(20)30137-1
PY  - 2020
SP  - 581-601
T2  - The Lancet. Psychiatry
TI  - Comparative efficacy and acceptability of antidepressants, psychotherapies, and their combination for acute treatment of children and adolescents with depressive disorder: a systematic review and network meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32563306
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32563306&amp;id=doi:10.1016%2FS2215-0366%2820%2930137-1&amp;issn=2215-0366&amp;isbn=&amp;volume=7&amp;issue=7&amp;spage=581&amp;pages=581-601&amp;date=2020&amp;title=The+Lancet.+Psychiatry&amp;atitle=Comparative+efficacy+and+acceptability+of+antidepressants%2C+psychotherapies%2C+and+their+combination+for+acute+treatment+of+children+and+adolescents+with+depressive+disorder%3A+a+systematic+review+and+network+meta-analysis.&amp;aulast=Zhou&amp;pid=%3Cauthor%3EZhou+X%3C%2Fauthor%3E%3CAN%3E32563306%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/306534/1-s2.0-S2215036620X00071/1-s2.0-S2215036620301371/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEIT%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQC0jr2Vcn9Ss%2BYULv7F2oEJROYTIqZnFG6l0CvtBRZsAQIhANDf7X6HFMWVOYmvgBysPVg9OXh9JjqVgAkFks70TlnDKrQDCCwQAxoMMDU5MDAzNTQ2ODY1Igz2h6IwAq9tPnJdr5gqkQMFCvMSDeB8ux9Oejxq6Qb7RYGQfdyIAokR%2FPUMjhT6wCZBHQKAPtHWEV3s4TQvf8emN71fZfzas3ZQ0iVbf9yIoV17moL0Di8XHUFYHevi63BxEm9vPMeNPDgGQmzWEARhQ8v%2FJuIS2%2FUwZ%2BwQkwSEtFBIWU%2BzaG1TJkF9nEwLQt7unaKXSas27dXU9t4NkLufh1RIy0bava6u8UgaOM2V8zWrXx4Lhk3qrhgbc9nvfQrm1CQLGycpA3VStoivh%2FT0604Vk1WNtKLDMLLTfS0LYcsGqPeAVOGH98ADgzxACu4olomdX%2FG011en5x4mjncWl0afIOPmFgNw1utk%2Bdh8dxz04d1keajOVJt4zE5d0s6OsxdOepxehovHShlyIX0hTd5qnHFwgji55uh%2FKWuT8%2BrsokHdC1EIkgOQywcVw%2FTsnJGji6zuv6vGLa0KoDk4JdXh%2BUUHriErc%2B9q9PY2AVN8mCWxPyy41fE3X%2BMuc9VtdgvKdZz11x%2BUtPrguJKzVD4%2FmrZUH%2FonHcg5Z3yjJDCcnqH4BTrqAVcDcToFjehE7V3QrPpnc7zXXqfx0Y6E5BeyH1g0K35DdLMrqcXgvxUWgz2Y5U%2FuYwlScU6UvtmIzQDlLzqwdojdc5MsUteGs6NAUGqvkWDMQ%2BhTIK0e7IgP3xB8b41y8da29HV4FwV4KQkUH7Maney%2BWGUs3pj5UkpdbWvL4gav%2FRMUtTiLl9e7lpLOJ9MHa0ri6rRwhx2fe8b8WstLH8GVEWvg6MWXK27tzx5jV03166efqvneR0NnOZcbM1P8AF%2B4dwWbV2BL9AlzLwVtPCyIodT6IGdvutyIGfA9rBk%2F%2BUd5PuNZ%2BcwhoA%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200710T122752Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY5LY7CY76%2F20200710%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=03be7c73c4bcaf7da1cab0909f2440bd45fab484cbaa7824cbf6e78c5038e09c&amp;hash=9f31487ee49066e54eab61f1caccee41ccf594530fc42748bf595226d4852fa1&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S2215036620301371&amp;tid=spdf-9d011a0a-e091-44d7-92e6-3f4e4c99de07&amp;sid=7db55e4a1e53c345f64a15b643c885f9597cgxrqb&amp;type=client
VL  - 7
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Recent randomized controlled trials (RCTs) claimed PUFAs to be effective for autism spectrum disorder (ASD) but international guidelines have not considered yet this body of evidence. Our aim was to assess the effectiveness of PUFAs in children and adolescents with ASD, for the Italian national guidelines on the management of ASD in children and adolescents.

METHODS: 
We performed a systematic review and meta-analysis of RCTs comparing PUFAs versus placebo or a healthy diet for the treatment of ASD in children and adolescents. The outcomes considered were deemed by the guideline panel to be highly relevant to children and adolescents with ASD and to their caregivers. The outcomes included hyperactivity, quality of sleep, self-harm, aggression, irritability, anxiety, attention, adaptive functioning, social interaction, restricted and repetitive interests and behavior, communication, hyperactivity and disruptive behaviors coexistent with core symptoms. The risk of bias of the included studies was assessed with the Cochrane tool, and the rating of the confidence in the effect estimates according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.

RESULTS: 
We included 9 studies with 405 participants. The strength of evidence ranged from low to very low. Six studies included preschoolers and school-age children, three studies included both children and adolescents. The majority of participants were males (83.8%), with a mean age of 6.7 years. PUFAs were superior compared to placebo in reducing anxiety in individuals with ASD (SMD -1.01, 95% CI - 1.86 to - 0.17; very low certainty of evidence). Moreover, PUFAs worsened quality of sleep compared to a healthy diet (SMD 1.11, 95% CI 0.21 to 2.00; very low certainty of evidence). PUFAs were not better than placebo in reducing aggression, hyperactivity, adaptive functioning, irritability, restricted and repetitive interests and behaviors and communication. Effects on some critical outcomes such as sleep, self-harm and disruptive behavior are currently unknown. The main limitations were the small number of participants included in the RCTs and the dosage which varied greatly (from 200 mg/day to 1540 mg/day), making it difficult to address causal inference.

CONCLUSIONS: 
PUFAs did not show evidence of effect in children and adolescents with ASD and the certainty of evidence as measured with the GRADE was low to very low. Further research is needed on this topic because the available evidence is inconclusive.
AD  - De Crescenzo, Franco. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy. f.decrescenzo@deplazio.it.De Crescenzo, Franco. Department of Psychiatry, University of Oxford, Oxford, UK. f.decrescenzo@deplazio.it.De Crescenzo, Franco. Pediatric University Hospital-Department (DPUO), Bambino Gesu Children&#039;s Hospital, Rome, Italy. f.decrescenzo@deplazio.it.D&#039;Alo, Gian Loreto. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.D&#039;Alo, Gian Loreto. School of Hygiene and Preventive Medicine, University of Rome Tor Vergata, Rome, Italy.Morgano, Gian Paolo. Department of Health Research Methods, Evidence and Impact (formerly Clinical Epidemiology and Biostatistics), McMaster GRADE Centre, McMaster University, Hamilton, Canada.Minozzi, Silvia. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Mitrova, Zuzana. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Saulle, Rosella. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Cruciani, Fabio. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Fulceri, Francesca. Research Coordination and Support Service, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Rome, Italy.Davoli, Marina. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.Scattoni, Maria Luisa. Research Coordination and Support Service, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Rome, Italy.Nardocci, Francesco. Research Coordination and Support Service, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Rome, Italy.Schunemann, Holger Jens. Department of Health Research Methods, Evidence and Impact (formerly Clinical Epidemiology and Biostatistics), McMaster GRADE Centre, McMaster University, Hamilton, Canada.Schunemann, Holger Jens. Michael G DeGroote Cochrane Canada Centre, McMaster University, Hamilton, Canada.Schunemann, Holger Jens. Department of Medicine, McMaster University, Hamilton, Canada.Amato, Laura. Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, 00154, Rome, Italy.
AN  - 32066439
AU  - De
AU  - Crescenzo,
AU  - F.
AU  - D&#039;Alo,
AU  - G.
AU  - L.
AU  - Morgano,
AU  - G.
AU  - P.
AU  - Minozzi,
AU  - S.
AU  - Mitrova,
AU  - Z.
AU  - Saulle,
AU  - R.
AU  - Cruciani,
AU  - F.
AU  - Fulceri,
AU  - F.
AU  - Davoli,
AU  - M.
AU  - Scattoni,
AU  - M.
AU  - L.
AU  - Nardocci,
AU  - F.
AU  - Schunemann,
AU  - H.
AU  - J.
AU  - Amato,
AU  - L.
AU  - Isaca
AU  - guideline
AU  - working
AU  - group
DA  - Feb 17
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12955-020-01284-5
DP  - Ovid Technologies
J2  - Health Qual Life Outcomes
L1  - internal-pdf://3049101722/De Crescenzo-2020-Impact of polyunsaturated fa.pdf
LA  - English
N1  - De Crescenzo, FrancoD&#039;Alo, Gian LoretoMorgano, Gian PaoloMinozzi, SilviaMitrova, ZuzanaSaulle, RosellaCruciani, FabioFulceri, FrancescaDavoli, MarinaScattoni, Maria LuisaNardocci, FrancescoSchunemann, Holger JensAmato, LauraISACA guideline working groupNardocci F
PY  - 2020
SP  - 28
T2  - Health &amp; Quality of Life Outcomes
TI  - Impact of polyunsaturated fatty acids on patient-important outcomes in children and adolescents with autism spectrum disorder: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32066439
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32066439&amp;id=doi:10.1186%2Fs12955-020-01284-5&amp;issn=1477-7525&amp;isbn=&amp;volume=18&amp;issue=1&amp;spage=28&amp;pages=28&amp;date=2020&amp;title=Health+%26+Quality+of+Life+Outcomes&amp;atitle=Impact+of+polyunsaturated+fatty+acids+on+patient-important+outcomes+in+children+and+adolescents+with+autism+spectrum+disorder%3A+a+systematic+review.&amp;aulast=De+Crescenzo&amp;pid=%3Cauthor%3EDe+Crescenzo+F%3C%2Fauthor%3E%3CAN%3E32066439%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://hqlo.biomedcentral.com/track/pdf/10.1186/s12955-020-01284-5
VL  - 18
ER  -
TY  - JOUR
AB  - Restricted interests of individuals with autism spectrum disorder (ASD) can act as a barrier to learning important life skills. Embedding the interests of individuals into their learning environment can act to establish motivation to participate. A meta-analysis of 20 single-case studies on embedding interests of individuals with ASD was conducted to determine overall effects and potential moderating variables. Data were aggregated across domains of variables including dependent variables, participant characteristics, and learning contexts. The correlation between self-stimulatory or ritualistic behaviors and primary outcomes was evaluated. Publication bias and consistency of the Tau/Tau-U nonoverlap effect size with visual analysis were tested via moderator analyses. The literature suggests that embedding interest for learners with ASD can either be beneficial or distractible. Effects ranged from negative to strong, with several moderators identified. Practitioners should take caution when using this intervention with students who display self-stimulatory or ritualistic behaviors when their interests are present. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Ninci, Jennifer: jninci@hawaii.eduNinci, Jennifer: University of Hawai&#039;i at Manoa, 1776 University Ave., Honolulu, HI, US, 96822, jninci@hawaii.eduNinci, Jennifer: University of Hawai&#039;i at Manoa, Honolulu, HI, USNeely, Leslie C.: University of Texas at San Antonio, San Antonio, TX, USBurke, Mack D.: Texas A&amp;M University, College Station, TX, USRispoli, Mandy: Purdue University, West Lafayette, IN, USVannest, Kimberly J.: Texas A&amp;M University, College Station, TX, USWillson, Victor: Texas A&amp;M University, College Station, TX, USUlloa, Paula: University of Hawai&#039;i at Manoa, Honolulu, HI, US
AN  - 2020-67354-004
AU  - Ninci,
AU  - J.
AU  - Neely,
AU  - L.
AU  - C.
AU  - Burke,
AU  - M.
AU  - D.
AU  - Rispoli,
AU  - M.
AU  - Vannest,
AU  - K.
AU  - J.
AU  - Willson,
AU  - V.
AU  - Ulloa,
AU  - P.
DA  - Sep
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/0741932519841692
DP  - Ovid Technologies
KW  - autism, interest, preference, embed, engagement
KW  - *Autism Spectrum Disorders
KW  - *Interests
KW  - *Learning
KW  - *School Based Intervention
KW  - *Student Engagement
KW  - Motivation
KW  - Students
KW  - Developmental Disorders &amp; Autism [3250]
KW  - Human
L1  - internal-pdf://0923493119/Ninci-2020.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
SP  - 296-308
T2  - Remedial and Special Education
TI  - A meta-analysis of single-case research on embedding interests of individuals with autism spectrum disorder
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-67354-004
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F0741932519841692&amp;issn=0741-9325&amp;isbn=&amp;volume=41&amp;issue=5&amp;spage=296&amp;pages=296-308&amp;date=2020&amp;title=Remedial+and+Special+Education&amp;atitle=A+meta-analysis+of+single-case+research+on+embedding+interests+of+individuals+with+autism+spectrum+disorder.&amp;aulast=Ninci&amp;pid=%3Cauthor%3ENinci%2C+Jennifer%3C%2Fauthor%3E%3CAN%3E2020-67354-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0741932519841692
VL  - 41
ER  -
TY  - JOUR
AB  - Self-injurious thoughts and behaviors (SITBs) are major public health concerns impacting a wide range of individuals and communities. Despite major efforts to develop and refine treatments to reduce SITBs, the efficacy of SITB interventions remains unclear. To provide a comprehensive summary of SITB treatment efficacy, we conducted a meta-analysis of published randomized controlled trials (RCTs) that have attempted to reduce SITBs. A total of 591 published articles from 1,125 unique RCTs with 3,458 effect sizes from the past 50 years were included. The random-effects meta-analysis yielded surprising findings: The overall intervention effects were small across all SITB outcomes; despite a near-exponential increase in the number of RCTs across five decades, intervention efficacy has not improved; all SITB interventions produced similarly small effects, and no intervention appeared significantly and consistently stronger than others; the overall small intervention effects were largely maintained at follow-up assessments; efficacy was similar across age groups, though effects were slightly weaker for child/adolescent populations and few studies focused on older adults; and major sample and study characteristics (e.g., control group type, treatment target, sample size, intervention length) did not consistently moderate treatment efficacy. This meta-analysis suggests that fundamental changes are needed to facilitate progress in SITB intervention efficacy. In particular, powerful interventions target the necessary causes of pathology, but little is known about SITB causes (vs. SITB correlates and risk factors). The field would accordingly benefit from the prioritization of research that aims to identify and target common necessary causes of SITBs. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
AD  - Fox, Kathryn R. University of Denver.Huang, Xieyining. Florida State University.Guzman, Eleonora M. Columbia University.Funsch, Kensie M. Florida State University.Cha, Christine B. Columbia University.Ribeiro, Jessica D. Florida State University.Franklin, Joseph C. Florida State University.
AN  - 33119344
AU  - Fox,
AU  - K.
AU  - R.
AU  - Huang,
AU  - X.
AU  - Guzman,
AU  - E.
AU  - M.
AU  - Funsch,
AU  - K.
AU  - M.
AU  - Cha,
AU  - C.
AU  - B.
AU  - Ribeiro,
AU  - J.
AU  - D.
AU  - Franklin,
AU  - J.
AU  - C.
DA  - Oct 29
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1037/bul0000305
DP  - Ovid Technologies
J2  - Psychol Bull
L1  - internal-pdf://1083599427/Fox-2020.pdf
LA  - English
N1  - Using Smart Source ParsingOctFox, Kathryn RHuang, XieyiningGuzman, Eleonora MFunsch, Kensie MCha, Christine BRibeiro, Jessica DFranklin, Joseph C
PY  - 2020
SP  - 29
T2  - Psychological Bulletin
TI  - Interventions for suicide and self-injury: A meta-analysis of randomized controlled trials across nearly 50 years of research
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33119344
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33119344&amp;id=doi:10.1037%2Fbul0000305&amp;issn=0033-2909&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Psychological+Bulletin&amp;atitle=Interventions+for+suicide+and+self-injury%3A+A+meta-analysis+of+randomized+controlled+trials+across+nearly+50+years+of+research.&amp;aulast=Fox&amp;pid=%3Cauthor%3EFox+KR%3C%2Fauthor%3E%3CAN%3E33119344%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 29
ER  -
TY  - JOUR
AB  - Increased levels of psychological stress during adolescence have been associated with a decline in academic performance, school dropout and increased risk of mental health problems. Intervening during this developmental period may prevent these problems. The school environment seems particularly suitable for interventions and over the past decade, various school-based stress reduction programs have been developed. The present study aims to evaluate the results of (quasi-)experimental studies on the effectiveness of school-based intervention programs targeting adolescent psychological stress and to investigate moderators of effectiveness. A three-level random effects meta-analytic model was conducted. The search resulted in the inclusion of k = 54 studies, reporting on analyses in 61 independent samples, yielding 123 effect sizes (N = 16,475 individuals). The results indicated a moderate overall effect on psychological stress. Yet, significant effects were only found in selected student samples. School-based intervention programs targeting selected adolescents have the potential to reduce psychological stress. Recommendations for practice, policy and future research are discussed.
AD  - van Loon, Amanda W G. Utrecht University Child and Adolescent Studies, Heidelberglaan 1, 3584 CS, Utrecht, The Netherlands. a.w.g.vanloon@uu.nl.Creemers, Hanneke E. University of Amsterdam Forensic Child and Youth Care Sciences, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands.Beumer, Wieke Y. Utrecht University Child and Adolescent Studies, Heidelberglaan 1, 3584 CS, Utrecht, The Netherlands.Okorn, Ana. Utrecht University Child and Adolescent Studies, Heidelberglaan 1, 3584 CS, Utrecht, The Netherlands.Vogelaar, Simone. Leiden University Developmental and Educational Psychology, Wassenaarseweg 52, 2333 AK, Leiden, The Netherlands.Saab, Nadira. Leiden University Graduate School of Teaching (ICLON), Kolffpad 1, 2333 BN, Leiden, The Netherlands.Miers, Anne C. Leiden University Developmental and Educational Psychology, Wassenaarseweg 52, 2333 AK, Leiden, The Netherlands.Westenberg, P Michiel. Leiden University Developmental and Educational Psychology, Wassenaarseweg 52, 2333 AK, Leiden, The Netherlands.Asscher, Jessica J. Utrecht University Child and Adolescent Studies, Heidelberglaan 1, 3584 CS, Utrecht, The Netherlands.Asscher, Jessica J. University of Amsterdam Forensic Child and Youth Care Sciences, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands.
AN  - 32034632
AU  - van
AU  - Loon,
AU  - A.
AU  - W.
AU  - G.
AU  - Creemers,
AU  - H.
AU  - E.
AU  - Beumer,
AU  - W.
AU  - Y.
AU  - Okorn,
AU  - A.
AU  - Vogelaar,
AU  - S.
AU  - Saab,
AU  - N.
AU  - Miers,
AU  - A.
AU  - C.
AU  - Westenberg,
AU  - P.
AU  - M.
AU  - Asscher,
AU  - J.
AU  - J.
DA  - Feb 07
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10964-020-01201-5
DP  - Ovid Technologies
J2  - J Youth Adolesc
L1  - internal-pdf://0036548874/van Loon-2020-Can Schools Reduce Adolescent Ps.pdf
LA  - English
N1  - Using Smart Source ParsingFebvan Loon, Amanda W GCreemers, Hanneke EBeumer, Wieke YOkorn, AnaVogelaar, SimoneSaab, NadiraMiers, Anne CWestenberg, P MichielAsscher, Jessica J
PY  - 2020
T2  - Journal of Youth &amp; Adolescence
TI  - Can Schools Reduce Adolescent Psychological Stress? A Multilevel Meta-Analysis of the Effectiveness of School-Based Intervention Programs
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32034632
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32034632&amp;id=doi:10.1007%2Fs10964-020-01201-5&amp;issn=0047-2891&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Journal+of+Youth+%26+Adolescence&amp;atitle=Can+Schools+Reduce+Adolescent+Psychological+Stress%3F+A+Multilevel+Meta-Analysis+of+the+Effectiveness+of+School-Based+Intervention+Programs.&amp;aulast=van+Loon&amp;pid=%3Cauthor%3Evan+Loon+AWG%3C%2Fauthor%3E%3CAN%3E32034632%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s10964-020-01201-5.pdf
VL  - 07
ER  -
TY  - JOUR
AB  - BACKGROUND: Low levels of physical activity, sedentary behaviour and mental health problems are issues that have received considerable attention in the last decade. The aim of this systematic review and meta-analysis was to investigate effects of interventions targeting school-related physical activity or sedentary behaviour on mental health in children and adolescents and to identify the features of effective interventions.

METHODS: Scientific articles published between January 2009 and October 2019 fulfilling the following criteria were included: general populations of children and adolescents between age 4 and 19, all types of school-related efforts to promote physical activity or reduce sedentary behaviour. Study selection, data extraction and quality assessment were done by at least two authors independently of each other. Data were analysed with a random effects meta-analysis and by narrative moderator analyses.

RESULTS: The literature search resulted in 10265 unique articles. Thirty-one articles, describing 30 interventions, were finally included. Eleven relevant outcomes were identified: health-related quality of life, well-being, self-esteem and self-worth, resilience, positive effect, positive mental health, anxiety, depression, emotional problems, negative effect and internalising mental health problems. There was a significant beneficial effect of school-related physical activity interventions on resilience (Hedges&#039; g = 0.748, 95% CI = 0.326; 1.170, p = 0.001), positive mental health (Hedges&#039; g = 0.405, 95% CI = 0.208; 0.603, p = &lt; 0.001), well-being (Hedges&#039; g = 0.877, 95% CI = 0.356; 1.398, p = &lt; 0.001) and anxiety (Hedges&#039; g = 0.347, 95% CI = 0.072; 0.623, p = 0.013). Heterogeneity was moderate to high (I&lt;sup&gt;2&lt;/sup&gt; = 59-98%) between studies for all outcomes except positive effect, where heterogeneity was low (I&lt;sup&gt;2&lt;/sup&gt; = 2%). The narrative moderator analyses of outcomes based on 10 or more studies showed that age of the children moderated the effect of the intervention on internalising mental health problems. Interventions in younger children showed a significantly negative or no effect on internalising mental health problems while those in older children showed a significant positive or no effect. Moreover, studies with a high implementation reach showed a significant negative or no effect while those with a low level of implementation showed no or a positive effect. No signs of effect moderation were found for self-esteem, well-being or positive mental health. Risk of publication bias was evident for several outcomes, but adjustment did not change the results.

CONCLUSIONS: School-related physical activity interventions may reduce anxiety, increase resilience, improve well-being and increase positive mental health in children and adolescents. Considering the positive effects of physical activity on health in general, these findings may reinforce school-based initiatives to increase physical activity. However, the studies show considerable heterogeneity. The results should therefore be interpreted with caution. Future studies should report on implementation factors and more clearly describe the activities of the control group and whether the activity is added to or replacing ordinary physical education lessons in order to aid interpretation of results.Trial registration: Prospero, crd42018086757.
AD  - Andermo, Susanne. Community Nutrition and Physical Activity, Department of Global Public Health, Karolinska Institutet, Solnavaegen 1E, 104 65, Stockholm, Sweden. Susanne.Andermo@ki.se.Hallgren, Mats. Epidemiology of Psychiatric Conditions, Substance Use and Social Environment, Department of Global Public Health, Karolinska Institutet, Solnavaegen 1E, 10465, Stockholm, Sweden.Nguyen, Thi-Thuy-Dung. Epidemiology of Psychiatric Conditions, Substance Use and Social Environment, Department of Global Public Health, Karolinska Institutet, Solnavaegen 1E, 10465, Stockholm, Sweden.Nguyen, Thi-Thuy-Dung. Center for Epidemiology and Community Medicine, Region Stockholm, Solnavaegen 1E, 104 65, Stockholm, Sweden.Jonsson, Sofie. Unit for Intervention and Implementation Research, Department of Environmental Medicine, Karolinska Institutet, Nobels vaeg 13, 17165, Solna, Sweden.Petersen, Solveig. Department of Living Conditions and Lifestyle, The Public Health Agency of Sweden, Nobels vag 18, 171 82, Solna, Sweden.Friberg, Marita. Department of Living Conditions and Lifestyle, The Public Health Agency of Sweden, Nobels vag 18, 171 82, Solna, Sweden.Romqvist, Anja. Department of Living Conditions and Lifestyle, The Public Health Agency of Sweden, Nobels vag 18, 171 82, Solna, Sweden.Stubbs, Brendon. Physiotherapy Department, South London and Maudsley NHS Foundation Trust, Denmark Hill, London, UK.Stubbs, Brendon. Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King&#039;s College London, De Crespigny Park, London, UK.Elinder, Liselotte Schafer. Community Nutrition and Physical Activity, Department of Global Public Health, Karolinska Institutet, Solnavaegen 1E, 104 65, Stockholm, Sweden.Elinder, Liselotte Schafer. Center for Epidemiology and Community Medicine, Region Stockholm, Solnavaegen 1E, 104 65, Stockholm, Sweden.
AN  - 32548792
AU  - Andermo,
AU  - S.
AU  - Hallgren,
AU  - M.
AU  - Nguyen,
AU  - T.
AU  - T.
AU  - Jonsson,
AU  - S.
AU  - Petersen,
AU  - S.
AU  - Friberg,
AU  - M.
AU  - Romqvist,
AU  - A.
AU  - Stubbs,
AU  - B.
AU  - Elinder,
AU  - L.
AU  - S.
DA  - Jun 16
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s40798-020-00254-x
DP  - Ovid Technologies
J2  - Sports Med Open
L1  - internal-pdf://0687385332/Andermo-2020-School-related physical activity.pdf
LA  - English
M3  - Review
N1  - Andermo, SusanneHallgren, MatsNguyen, Thi-Thuy-DungJonsson, SofiePetersen, SolveigFriberg, MaritaRomqvist, AnjaStubbs, BrendonElinder, Liselotte Schafer
PY  - 2020
SP  - 25
T2  - Sports Medicine - Open
TI  - School-related physical activity interventions and mental health among children: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32548792
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32548792&amp;id=doi:10.1186%2Fs40798-020-00254-x&amp;issn=2199-1170&amp;isbn=&amp;volume=6&amp;issue=1&amp;spage=25&amp;pages=25&amp;date=2020&amp;title=Sports+Medicine+-+Open&amp;atitle=School-related+physical+activity+interventions+and+mental+health+among+children%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Andermo&amp;pid=%3Cauthor%3EAndermo+S%3C%2Fauthor%3E%3CAN%3E32548792%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297899/pdf/40798_2020_Article_254.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - School-wide positive behavior interventions and supports (SWPBIS) is a multitiered support framework for preventing problem behaviors and increasing prosocial behaviors. There has been an increasing number of experimental group design research studies focused on the impacts of SWPBIS. 

Therefore, we conducted a systematic review to update and extend prior reviews by including both published and unpublished studies and conducting a robust variance estimation meta-analysis to examine the magnitude of the effect of SWPBIS on all available school-level outcomes. 

A total of 29 studies were identified across the United States and Europe, including seven randomized controlled trials and 22 quasi-experimental group design studies. Overall, statistically significant reductions in school discipline and increased academic achievement were found. Effect sizes were small to medium. Limitations and implications are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Gage, Nicholas A.: gagenicholas@coe.ufl.eduGage, Nicholas A.: School of Special Education, School Psychology, &amp; Early Childhood Studies, University of Florida, 1403 Norman Hall, PO Box 117050, Gainesville, FL, US, 32611, gagenicholas@coe.ufl.eduLee, Ahhyun: School of Special Education, School Psychology, and Early Childhood Studies, College of Education, University of Florida, Gainesville, FL, USGage, Nicholas A.: School of Special Education, School Psychology, and Early Childhood Studies, College of Education, University of Florida, Gainesville, FL, US
AN  - 2020-01373-001
AU  - Lee,
AU  - A.
AU  - Gage,
AU  - N.
AU  - A.
DA  - May
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/pits.22336
DP  - Ovid Technologies
KW  - academic achievement, organizational health, school discipline, school- level outcomes, school- wide positive behavior intervention and support, SWPBIS
KW  - *Academic Achievement
KW  - *Behavior Therapy
KW  - *Classroom Discipline
KW  - *School Based Intervention
KW  - Organizations
KW  - Curriculum &amp; Programs &amp; Teaching Methods [3530]
KW  - Human
L1  - internal-pdf://1646268953/Lee-2020.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2020
SP  - 783-804
T2  - Psychology in the Schools
TI  - Updating and expanding systematic reviews and meta-analyses on the effects of school-wide positive behavior interventions and supports
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-01373-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1002%2Fpits.22336&amp;issn=0033-3085&amp;isbn=&amp;volume=57&amp;issue=5&amp;spage=783&amp;pages=783-804&amp;date=2020&amp;title=Psychology+in+the+Schools&amp;atitle=Updating+and+expanding+systematic+reviews+and+meta-analyses+on+the+effects+of+school-wide+positive+behavior+interventions+and+supports.&amp;aulast=Lee&amp;pid=%3Cauthor%3ELee%2C+Ahhyun%3C%2Fauthor%3E%3CAN%3E2020-01373-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/pits.22336
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pits.22336?download=true
VL  - 57
ER  -
TY  - JOUR
AB  - **Objective:** 
The effect of vitamin D supplementation on the risk of Autism Spectrum Disorder (ASD) is conflicting. The aim of this study was to estimate the efficacy of vitamin D supplementation on ASD in children. 

**Method(s):** 
We conducted a meta-analysis of randomized controlled trials (RCTs) in which vitamin D supplementation was used as a therapy in children with ASD. The PubMed, PsychINFO, Cochrane CENTRAL library, Web of Science, and Cinahl databases were searched from inception to March 20, 2019, for all publications on vitamin D and ASD with no restrictions. Studies involving individuals aged &lt;18 years diagnosed with ASD and with all functional outcomes assessed by measurement scales for ASD were included. Mean differences were pooled, and a meta-analysis was performed using a random-effects model due to differences between the individual RCTs. 

**Result(s):** 
There were five RCTs with 349 children with ASD in the review, of which three RCTs were included in the meta-analysis. Vitamin D supplementation indicated a small but significant improvement in hyperactivity scores (pooled MD: -3.20; 95% CI: [-6.06, -0.34]) with low heterogeneity (I&lt;sup&gt;2&lt;/sup&gt; = 10%, p = 0.33), but there were no other statistically significant differences in ASD symptoms between groups as measured by validated scales. 

**Conclusion(s):**
 Vitamin D supplementation appears to be beneficial for hyperactivity but not for core symptoms or other co-existing behaviors and conditions of ASD. Future RCTs with large sample sizes examining the effect of vitamin D supplementation on ASD among individuals with low serum vitamin D levels at baseline are needed. Copyright &copy; 2020 The Author(s). Published by Informa UK Limited, trading as Taylor &amp; Francis Group.
AD  - (Li, Xu, Zhang, Zhang, Wu, Wang, Zhu) Henan Key Laboratory of Child Brain Injury, Third Affiliated Hospital and Institute of Neuroscience of Zhengzhou University, Zhengzhou, China (Wang) Center of Perinatal Medicine and Health, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (Zhu) Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (Zhu) Department of Women&#039;s and Children&#039;s Health, Karolinska Institutet, Stockholm, SwedenC. Zhu, Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg 40530, Sweden. E-mail: changlian.zhu@neuro.gu.se
AN  - 2006085754
AU  - Li,
AU  - B.
AU  - Xu,
AU  - Y.
AU  - Zhang,
AU  - X.
AU  - Zhang,
AU  - L.
AU  - Wu,
AU  - Y.
AU  - Wang,
AU  - X.
AU  - Zhu,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/1028415X.2020.1815332
DP  - Ovid Technologies
KW  - autism spectrum disorders
KW  - children
KW  - core symptoms
KW  - docosahexaenoic acid
KW  - hyperactivity
KW  - meta-analysis
KW  - randomized controlled trials
KW  - systematic review
KW  - Vitamin D supplementation
KW  - autism
KW  - child
KW  - Cinahl
KW  - clinical trial
KW  - Cochrane Library
KW  - controlled study
KW  - drug efficacy
KW  - drug therapy
KW  - female
KW  - human
KW  - human tissue
KW  - male
KW  - Medline
KW  - meta analysis
KW  - PsycINFO
KW  - randomized controlled trial (topic)
KW  - review
KW  - sample size
KW  - vitamin blood level
KW  - Web of Science
KW  - vitamin D
L1  - internal-pdf://4045427189/Li-2020-The effect of vitamin D supplementatio.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - Nutritional Neuroscience.
TI  - The effect of vitamin D supplementation in treatment of children with autism spectrum disorder: a systematic review and meta-analysis of randomized controlled trials
UR  - http://www.tandfonline.com/loi/ynns20#.VvukQLdf1Hh
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2006085754
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1080%2F1028415X.2020.1815332&amp;issn=1028-415X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=&amp;date=2020&amp;title=Nutritional+Neuroscience&amp;atitle=The+effect+of+vitamin+D+supplementation+in+treatment+of+children+with+autism+spectrum+disorder%3A+a+systematic+review+and+meta-analysis+of+randomized+controlled+trials&amp;aulast=Li&amp;pid=%3Cauthor%3ELi+B.%3C%2Fauthor%3E%3CAN%3E2006085754%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/pdf/10.1080/1028415X.2020.1815332?needAccess=true
ER  -
TY  - JOUR
AB  - Online parenting programs can increase the accessibility of mental health services. This meta-analysis investigated the effectiveness of online parenting interventions in reducing children and adolescents behavior problems (primary outcome) and improving parenting behavior, parent distress, and parenting efficacy (secondary outcomes). A systematic search was conducted on PubMed, PsycInfo, Web of Science, SCOPUS, and ProQuest on June 28th, 2019. The meta-analysis was prior registered in PROSPERO. In total, 2160 records were identified and 15 Randomized Controlled Trials (RCTs) were included (N = 1668) in the systematic review and meta-analysis. The quality of each study was assessed by two independent evaluators. When compared to waitlist, online parenting interventions are effective in reducing behavior problems with a small effect size (Hedges&#039;s g = 0.40). No significant differences were found between online and classical delivered parenting interventions in reducing behavior problems (g = - 0.07). Compared to waitlist, the interventions are effective in improving parenting behavior (g = 0.34), parent distress (g = 0.30), and parenting efficacy (g = 0.41). The results appear to be stable at follow-up measures. The factors responsible for the effectiveness of the interventions were explored through moderation analyses. Online parenting interventions are promising for improving both behavior problems and parent outcomes. Future studies should focus on methods to increase their effectiveness and measure the outcomes more objectively.
AD  - Florean, Ionut Stelian. International Institute for the Advanced Studies of Psychotherapy and Applied Mental Health, Babes-Bolyai University, Cluj-Napoca, Romania.Florean, Ionut Stelian. Evidence Based Psychological Assessment and Interventions Doctoral School, Babes-Bolyai University, Cluj-Napoca, Romania.Dobrean, Anca. International Institute for the Advanced Studies of Psychotherapy and Applied Mental Health, Babes-Bolyai University, Cluj-Napoca, Romania. ancadobrean@psychology.ro.Dobrean, Anca. Department of Clinical Psychology and Psychotherapy, Babes-Bolyai University, Republicii Street 37, 400015, Cluj-Napoca, Romania. ancadobrean@psychology.ro.Pasarelu, Costina Ruxandra. International Institute for the Advanced Studies of Psychotherapy and Applied Mental Health, Babes-Bolyai University, Cluj-Napoca, Romania.Pasarelu, Costina Ruxandra. Department of Clinical Psychology and Psychotherapy, Babes-Bolyai University, Republicii Street 37, 400015, Cluj-Napoca, Romania.Georgescu, Raluca Diana. International Institute for the Advanced Studies of Psychotherapy and Applied Mental Health, Babes-Bolyai University, Cluj-Napoca, Romania.Georgescu, Raluca Diana. Evidence Based Psychological Assessment and Interventions Doctoral School, Babes-Bolyai University, Cluj-Napoca, Romania.Milea, Ion. International Institute for the Advanced Studies of Psychotherapy and Applied Mental Health, Babes-Bolyai University, Cluj-Napoca, Romania.Milea, Ion. Evidence Based Psychological Assessment and Interventions Doctoral School, Babes-Bolyai University, Cluj-Napoca, Romania.
AN  - 32897527
AU  - Florean,
AU  - I.
AU  - S.
AU  - Dobrean,
AU  - A.
AU  - Pasarelu,
AU  - C.
AU  - R.
AU  - Georgescu,
AU  - R.
AU  - D.
AU  - Milea,
AU  - I.
DA  - Sep 08
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-020-00326-0
DP  - Ovid Technologies
J2  - Clin Child Fam Psychol Rev
L1  - internal-pdf://0478432578/Florean-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingSepFlorean, Ionut StelianDobrean, AncaPasarelu, Costina RuxandraGeorgescu, Raluca DianaMilea, Ion
PY  - 2020
SP  - 08
T2  - Clinical Child &amp; Family Psychology Review
TI  - The Efficacy of Internet-Based Parenting Programs for Children and Adolescents with Behavior Problems: A Meta-Analysis of Randomized Clinical Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32897527
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32897527&amp;id=doi:10.1007%2Fs10567-020-00326-0&amp;issn=1096-4037&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Clinical+Child+%26+Family+Psychology+Review&amp;atitle=The+Efficacy+of+Internet-Based+Parenting+Programs+for+Children+and+Adolescents+with+Behavior+Problems%3A+A+Meta-Analysis+of+Randomized+Clinical+Trials.&amp;aulast=Florean&amp;pid=%3Cauthor%3EFlorean+IS%3C%2Fauthor%3E%3CAN%3E32897527%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10567-020-00326-0
UR  - https://link.springer.com/content/pdf/10.1007/s10567-020-00326-0.pdf
VL  - 08
ER  -
TY  - JOUR
AB  - Technology-assisted interventions have been identified as a means to increase accessibility and enhance engagement of parenting programs. The current meta-analytic review examines the effectiveness of these interventions in families experiencing social disadvantage. A literature search was conducted spanning March 2007-June 2019. Nine studies met inclusion criteria (total of 864 participants) which included an evaluation of a parenting intervention for families with at least one of the following demographic challenges, low socioeconomic status, single parenthood, and/or young parenthood. Interventions (or a component of the intervention) were delivered by computer, cell phone, smartphone, and/or tablet. Data were organized into three categories: parental psychological well-being (e.g., self-esteem, social support), parenting (e.g., observed or self-reported parenting behavior), and child behavior (e.g., disruptive behavior). Effect sizes (Hedges&#039; g) were calculated and moderators (i.e., contact with an interventionist, intervention length, publication year, % female parents, mean parent age, parental education, % minority, and child age) were examined through Q-statistics and meta-regression, as appropriate. Intervention showed a near-significant impact on parental psychological well-being (g = .35, p = .051). Furthermore, interventions that did not include direct contact with an interventionist showed no evidence of effectiveness (g = - .02); interventions that incorporated contact were significantly more effective (g = .68). In addition, intervention length moderated intervention effectiveness; shorter interventions yielded greater improvements in well-being, compared with longer interventions. Interventions were also associated with significant improvements in parenting (g = .38) and child behavior (g = .39). These findings provide support for the use of technology-assisted parenting interventions in populations experiencing social disadvantage.
AD  - Harris, Madeleine. Graduate Neuroscience Program, McMaster University, Hamilton, ON, L8S 4K1, Canada.Harris, Madeleine. Offord Centre for Child Studies, McMaster University, Hamilton, ON, L8S 4K1, Canada.Andrews, Krysta. Graduate Neuroscience Program, McMaster University, Hamilton, ON, L8S 4K1, Canada.Andrews, Krysta. Offord Centre for Child Studies, McMaster University, Hamilton, ON, L8S 4K1, Canada.Gonzalez, Andrea. Offord Centre for Child Studies, McMaster University, Hamilton, ON, L8S 4K1, Canada.Gonzalez, Andrea. Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, L8S 4K1, Canada.Prime, Heather. Offord Centre for Child Studies, McMaster University, Hamilton, ON, L8S 4K1, Canada.Prime, Heather. Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, L8S 4K1, Canada.Atkinson, Leslie. Department of Psychology, Ryerson University, Toronto, ON, M5B 2K3, Canada. atkinson@psych.ryerson.ca.
AN  - 32415543
AU  - Harris,
AU  - M.
AU  - Andrews,
AU  - K.
AU  - Gonzalez,
AU  - A.
AU  - Prime,
AU  - H.
AU  - Atkinson,
AU  - L.
DA  - May 15
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s11121-020-01128-0
DP  - Ovid Technologies
J2  - Prev Sci
L1  - internal-pdf://4054284526/Harris-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingMayHarris, MadeleineAndrews, KrystaGonzalez, AndreaPrime, HeatherAtkinson, Leslie
PY  - 2020
T2  - Prevention Science
TI  - Technology-Assisted Parenting Interventions for Families Experiencing Social Disadvantage: a Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32415543
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32415543&amp;id=doi:10.1007%2Fs11121-020-01128-0&amp;issn=1389-4986&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Prevention+Science&amp;atitle=Technology-Assisted+Parenting+Interventions+for+Families+Experiencing+Social+Disadvantage%3A+a+Meta-Analysis.&amp;aulast=Harris&amp;pid=%3Cauthor%3EHarris+M%3C%2Fauthor%3E%3CAN%3E32415543%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs11121-020-01128-0
UR  - https://link.springer.com/content/pdf/10.1007/s11121-020-01128-0.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - **Aims**. Mental disorders in children are a significant and growing cause of morbidity worldwide. Although interventions to help overcome barriers along the pathway to accessing health care for children with mental disorders exist, there is no overview of randomised controlled trials (RCTs) on these interventions as yet. This study aimed to systematically identify RCTs of interventions to improve access to mental health care for children and synthesise them using a conceptual framework of access to health care. Methods. This systematic review was performed following a predefined protocol registered with PROSPERO (ID: CRD42018081714). We searched the databases MEDLINE, EMBASE, PsycINFO and CENTRAL for RCTs up to 15 May 2019 using terms related to the concepts &#039;young people,&#039; &#039;mental disorders&#039; and &#039;help-seeking interventions&#039; and scanned reference lists from relevant studies. Two reviewers independently screened all identified articles in a two-stage process, extracted results on outcomes of interest (knowledge, attitudes, intentions, help-seeking, accessing care, mental health outcomes and satisfaction), assessed the risk of bias and conducted meta-analyses where deemed appropriate. 

**Results**. After screening 5641 identified articles, 34 RCTs were eligible for inclusion. Eighty per cent of universal school-based interventions measuring knowledge (n = 5) and 67% measuring attitudes (n = 6) reported significantly better results compared with controls on those outcomes, whereas 20% measuring access to care (n = 5) and none measuring mental health outcomes (n = 7) did. In contrast, 71% of interventions targeting at-risk individuals (n = 21) reported better access to care compared with controls, while just 33% (n = 6) did for mental health outcomes. For satisfaction with care, this proportion was 80% (n = 5). Meta-analyses of interventions measuring initial appointment attendance yielded combined odds ratios of 3.11 (2.07-4.67) for appointment reminder interventions and 3.51 (2.02-6.11) for treatment engagement interventions. The outcomes for universal school-based interventions were heterogeneous and could not be summarised quantitatively through meta-analysis. 

**Conclusions**. To have a population-level effect on improving children&#039;s access to mental health care, two-stage interventions that identify those in need and then engage them in the health-care system may be necessary. We need more evidence on interventions to target contextual factors such as affordability and infrastructural barriers.
AN  - WOS:000585066900033
AU  - Werlen,
AU  - L.
AU  - Gjukaj,
AU  - D.
AU  - Mohler-Kuo,
AU  - M.
AU  - Puhan,
AU  - M.
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1017/S2045796019000544
L1  - internal-pdf://1059784874/Werlen-2020.pdf
PY  - 2020
T2  - EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
TI  - Interventions to improve children&#039;s access to mental health care: a systematic review and meta-analysis
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/87A33E5BB718F1126A07DF43D2A7D374/S2045796019000544a.pdf/div-class-title-interventions-to-improve-children-s-access-to-mental-health-care-a-systematic-review-and-meta-analysis-div.pdf
VL  - 29
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Depressive disorders can affect long-term mental and physical health functioning among children and adolescents, including increased risk of suicide. Despite access to several nonpharmacological, pharmacological, and combined treatment options for childhood depression, clinicians contend with sparse evidence and are concerned about harms associated with treatment.

METHODS: 
We conducted a systematic review to evaluate the efficacy, comparative effectiveness, and moderators of benefits and harms of available nonpharmacological and pharmacological treatments for children and adolescents with a confirmed diagnosis of a depressive disorder (DD)-major depressive disorder (MDD), persistent depressive disorder (previously termed dysthymia) or DD not otherwise specified. We searched five databases and other sources for evidence available from inception to May 29, 2019, dually screened the results, and analyzed eligible studies.

RESULTS: 
We included in our analyses data from 60 studies (94 articles) that met our review eligibility criteria. For adolescents (study participants&#039; ages range from 12 to 18 years) with MDD, cognitive behavioral therapy (CBT), fluoxetine, escitalopram, and combined fluoxetine and CBT may improve depressive symptoms (1 randomized controlled trial [RCT] each, n ranges from 212 to 311); whether the magnitude of improvement is clinically significant is unclear. Among adolescents or children with MDD, CBT plus medications (8-17 years) may be associated with lower rates of relapse (1 RCT [n = 121]). In the same population (6-17 years), selective serotonin reuptake inhibitors (SSRIs) may be associated with improved response (7 RCTs [n = 1,525]; risk difference [RD], 72/1,000 [95% confidence interval (CI), 2 to 24], I&lt;sup&gt;2&lt;/sup&gt; = 9%) and functional status (5 RCTs [n = 941]; standardized mean difference, 0.16 [95% CI, 0.03 to 0.29]; I&lt;sup&gt;2&lt;/sup&gt; = 0%). For adolescents or children with any DD (7-18 years), CBT or family therapy may be associated with improvements in symptoms, response, or functional status (1 RCT each, n ranges from 64 to 99). Among children with any DD (7-12 years), family-based interpersonal therapy may be associated with improved symptoms (1 RCT, n = 38). Psychotherapy trials did not report harms. SSRIs may be associated with a higher risk of serious adverse events among adolescents or children with MDD (7-18 years; 9 RCTs [n = 2,206]; RD, 20/1,000 [95% CI, 1 to 440]; I&lt;sup&gt;2&lt;/sup&gt;, 4%) and with a higher risk of withdrawal due to adverse events among adolescents with MDD (12-18 years; 4 RCTs [n = 1,296], RD, 26/1,000 [95% CI, 6 to 45]; I&lt;sup&gt;2&lt;/sup&gt;, 0%). Paroxetine (1 RCT [n = 180]) may be associated with a higher risk of suicidal ideation or behaviors among adolescents with MDD (12-18 years). Evidence was insufficient to judge the risk of suicidal ideation or behavior for other SSRIs for adolescents and children with MDD or other DD (7-18 years) (10 RCTs [n = 2,368]; relative risk, 1.14 [95% CI, 0.89 to 1.45]; I&lt;sup&gt;2&lt;/sup&gt;, 8%). However, this report excluded data on inpatients and those without depressive disorders, whom the Food and Drug Administration included in finding an increased risk of suicidality for all antidepressants across all indications.

CONCLUSIONS: 
Efficacious treatments exist for adolescents with MDD. SSRIs may be associated with increased withdrawal and serious adverse events. No evidence on harms of psychotherapy were identified.
AN  - 32298061
AU  - Viswanathan,
AU  - M.
AU  - Kennedy,
AU  - S.
AU  - M.
AU  - McKeeman,
AU  - J.
AU  - Christian,
AU  - R.
AU  - Coker-Schwimmer,
AU  - M.
AU  - Cook
AU  - Middleton,
AU  - J.
AU  - Bann,
AU  - C.
AU  - Lux,
AU  - L.
AU  - Randolph,
AU  - C.
AU  - Forman-Hoffman,
AU  - V.
DA  - 04
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.23970/AHRQEPCCER224
DP  - Ovid Technologies
J2  - Agency for Healthcare Research and Quality (US)
L1  - internal-pdf://2152758564/Bookshelf_NBK555853.pdf
LA  - English
M3  - Review
N1  - Using Smart Source Parsing20-EHC005-EFViswanathan, MeeraKennedy, Sara M.McKeeman, JoniChristian, RobertCoker-Schwimmer, MannyCook Middleton, JenniferBann, CarlaLux, LindaRandolph, CharliForman-Hoffman, Valerie
PY  - 2020
T2  - Agency for Healthcare Research and Quality
TI  - Treatment of Depression in Children and Adolescents: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32298061
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32298061&amp;id=doi:&amp;issn=&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=%3D%3D%3D&amp;atitle=Treatment+of+Depression+in+Children+and+Adolescents%3A+A+Systematic+Review&amp;aulast=Viswanathan&amp;pid=%3Cauthor%3EViswanathan+M%3C%2Fauthor%3E%3CAN%3E32298061%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - BACKGROUND: Violence exposure (direct, indirect, individual, structural) affects youth mental health.

OBJECTIVE: We aimed to evaluate the effectiveness of psychosocial interventions in addressing the sequelae of violence exposure on youth (15-24 years old) and evaluate whether moderating factors impact intervention effectiveness.

METHODS: We systematically searched eight databases and reference lists to retrieve any studies of psychosocial interventions addressing mental health among youth aged 15-25 exposed to violence. We assessed study risk of bias using an adapted version of the Downs and Black&#039;s Risk of Bias Scale.

RESULTS: We identified n = 3077 studies. Sixteen articles representing 14 studies met were included. The studies assessed direct and indirect individual violence exposure at least once. We pooled the data from the 14 studies and evaluated the effects. We estimated an average effect of r+ = 0.57 (RCTs: 95 % CI 0.02-1.13; observational studies: 95 % CI 0.27-86) with some heterogeneity (RCTs: I&lt;sup&gt;2&lt;/sup&gt; = 78.03, longitudinal studies: I&lt;sup&gt;2&lt;/sup&gt; = 82.93). The most effective interventions are Cognitive Behavioral Therapy, and Exposure Therapy with an exposure focus. However, due to the small number of studies we are uncertain about benefits of interventions.

CONCLUSIONS: No study assessed structural violence. Therefore, studies are needed to evaluate the effects of psychosocial interventions for youth exposed to direct, indirect, individual and structural violence.
AD  - Lindert, Jutta. University of Applied Sciences Emden/Leer, Emden, Germany; WRSC, Brandeis University, Waltham, United States. Electronic address: Jutta.Lindert@hs-emden-leer.de.Jakubauskiene, Marija. University of Vilnius, Faculty of Medicine, Vilnius, Lithuania.Natan, Marta. University of Applied Sciences Emden/Leer, Emden, Germany.Wehrwein, Annette. University of Applied Sciences Emden/Leer, Emden, Germany.Bain, Paul. Countway Library, Harvard School of Public Health, Boston, United States.Schmahl, Christian. Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany; Department of Psychiatry, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.Kamenov, Kaloyan. Instituto de salud Carlos III, Centro de investigacion biomedica en salud mental (CIBERSAM), Departamento de psiquiatria, Universidad Autonoma de Madrid.Carta, Mauro. Liaison Psychiatry Unit, University Hospital, Department of Medical Sciences and Public Health, University of Cagliari, Italy.Cabello, Maria. Countway Library, Harvard School of Public Health, Boston, United States.
AN  - 32805619
AU  - Lindert,
AU  - J.
AU  - Jakubauskiene,
AU  - M.
AU  - Natan,
AU  - M.
AU  - Wehrwein,
AU  - A.
AU  - Bain,
AU  - P.
AU  - Schmahl,
AU  - C.
AU  - Kamenov,
AU  - K.
AU  - Carta,
AU  - M.
AU  - Cabello,
AU  - M.
DA  - Aug 14
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.chiabu.2020.104530
DP  - Ovid Technologies
J2  - Child Abuse Negl
L1  - internal-pdf://2909615163/Lindert-2020.pdf
LA  - English
N1  - Lindert, JuttaJakubauskiene, MarijaNatan, MartaWehrwein, AnnetteBain, PaulSchmahl, ChristianKamenov, KaloyanCarta, MauroCabello, MariaS0145-2134(20)30185-X
PY  - 2020
SP  - 104530
T2  - Child Abuse &amp; Neglect
TI  - Psychosocial interventions for violence exposed youth - A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32805619
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32805619&amp;id=doi:10.1016%2Fj.chiabu.2020.104530&amp;issn=0145-2134&amp;isbn=&amp;volume=108&amp;issue=&amp;spage=104530&amp;pages=104530&amp;date=2020&amp;title=Child+Abuse+%26+Neglect&amp;atitle=Psychosocial+interventions+for+violence+exposed+youth+-+A+systematic+review.&amp;aulast=Lindert&amp;pid=%3Cauthor%3ELindert+J%3C%2Fauthor%3E%3CAN%3E32805619%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 108
ER  -
TY  - JOUR
AB  - In 1998, Ost published [One-session treatment of specific phobias-a rapid and effective method] [in Swedish] giving rise to the idea that brief, intensive, and concentrated psychosocial interventions could exhibit public health impact. At this juncture, and per criteria of the Society for Clinical Child and Adolescent Psychology, there are data supporting that brief, non-pharmacological intervention [prescriptions] for pediatric anxiety can be considered well-established or probably efficacious. In addition, data from 76 randomized controlled trials (N = 17,203 youth) yield an overall mean effect size of 0.19 on pediatric anxiety outcomes (pre-post). Note, however, that effect sizes vary significantly. These data point to the capacity for clinical change coming from in-vivo exposures for specific phobias (~3 h, one session), CBT with social skills training (~3 h, six sessions for indicated prevention and early intervention), and CBT-based parent training (~6 h, eight digital modules with clinician support). Given such evidence, we recommend efforts be made to establish ways to position such treatment innovations for rapid deployment facilitated by high-quality training, monitoring, technical assistance, and ongoing disclosures.
AD  - Stoll, Ryan D. Department of Psychology, Arizona State University.Pina, Armando A. Department of Psychology, Arizona State University.Schleider, Jessica. Department of Psychology, Stony Brook University.
AN  - 32285692
AU  - Stoll,
AU  - R.
AU  - D.
AU  - Pina,
AU  - A.
AU  - A.
AU  - Schleider,
AU  - J.
DA  - Apr 14
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/15374416.2020.1738237
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
L1  - internal-pdf://0870629430/Stoll-2020-Brief, Non-Pharmacological, Interve.pdf
LA  - English
N1  - Stoll, Ryan DPina, Armando ASchleider, Jessica
PY  - 2020
SP  - 1-27
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Brief, Non-Pharmacological, Interventions for Pediatric Anxiety: Meta-Analysis and Evidence Base Status
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32285692
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32285692&amp;id=doi:10.1080%2F15374416.2020.1738237&amp;issn=1537-4416&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-27&amp;date=2020&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Brief%2C+Non-Pharmacological%2C+Interventions+for+Pediatric+Anxiety%3A+Meta-Analysis+and+Evidence+Base+Status.&amp;aulast=Stoll&amp;pid=%3Cauthor%3EStoll+RD%3C%2Fauthor%3E%3CAN%3E32285692%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/full/10.1080/15374416.2020.1738237
UR  - https://www.tandfonline.com/doi/pdf/10.1080/15374416.2020.1738237?needAccess=true
ER  -
TY  - JOUR
AB  - There is high variability in efficacy for interventions for youth with disruptive behavior problems (DBP). Despite evidence of the unique correlates and critical consequences of girls&#039; DBP, there is a dearth of research examining treatment efficacy for girls. This meta-analysis of 167 unique effect sizes from 29 studies (28,483 youth, 50% female; median age: 14) suggests that existing treatments have a medium positive effect on DBP (g = .33). For both boys and girls, the most effective interventions included (a) multimodal or group format, (b) cognitive skills or family systems interventions, and (c) length-intensive programs for (d) younger children. Boys demonstrated significantly greater treatment gains from group format interventions compared to girls, which is particularly important given that the group program format was the most prevalent format for boys and girls, with 14 studies involving 10,433 youth encompassing this category. This is the first meta-analysis to examine the effect of program characteristics in a sample of programs selected to be specifically inclusive of girls. Given that girls are underrepresented in intervention research on DBP, findings are discussed in terms of gender-responsive considerations and elucidating how key aspects of program structure can support more effective intervention outcomes for youth. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - Javdani, Shabnam: shabnam.javdani@nyu.eduJavdani, Shabnam, shabnam.javdani@nyu.eduGranski, Megan: Department of Applied Psychology, Steinhardt School of Culture, Education, and Human Development, New York University, New York, NY, USJavdani, Shabnam: Department of Applied Psychology, Steinhardt School of Culture, Education, and Human Development, New York University, New York, NY, USAnderson, Valerie R.: School of Criminal Justice, University of Cincinnati, Cincinnati, OH, USCaires, Roxane: Department of Applied Psychology, Steinhardt School of Culture, Education, and Human Development, New York University, New York, NY, US
AN  - 2019-51086-001
AU  - Granski,
AU  - Megan
AU  - Javdani,
AU  - Shabnam
AU  - Anderson,
AU  - Valerie
AU  - R.
AU  - Caires,
AU  - Roxane
DA  - Mar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/ajcp.12377
DP  - Ovid Technologies
KW  - Disruptive behavior problems, Delinquency, Girls/gender, program characteristics, Intervention/treatment
KW  - *Behavior Problems
KW  - *Family Intervention
KW  - *Human Sex Differences
KW  - *Juvenile Delinquency
KW  - *Multimodal Treatment Approach
KW  - Community &amp; Social Services [3373]
KW  - Human
L1  - internal-pdf://4230004150/granski.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
SP  - 201-222
T2  - American Journal of Community Psychology
TI  - A meta-analysis of program characteristics for youth with disruptive behavior problems: The moderating role of program format and youth gender
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2019-51086-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1002%2Fajcp.12377&amp;issn=0091-0562&amp;isbn=&amp;volume=65&amp;issue=1-2&amp;spage=201&amp;pages=201-222&amp;date=2020&amp;title=American+Journal+of+Community+Psychology&amp;atitle=A+meta-analysis+of+program+characteristics+for+youth+with+disruptive+behavior+problems%3A+The+moderating+role+of+program+format+and+youth+gender.&amp;aulast=Granski&amp;pid=%3Cauthor%3EGranski%2C+Megan%3C%2Fauthor%3E%3CAN%3E2019-51086-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/full/10.1002/ajcp.12377
VL  - 65
ER  -
TY  - JOUR
AB  - Attention Deficit Hyperactivity Disorder (ADHD) is the most common neuropsychiatric condition in childhood and adolescence. Psychoeducation has been recommended by different guidelines as an initial treatment for ADHD, however the effects of the intervention for reducing symptoms and improving other outcomes still need to be established. This systematic review investigated the magnitude of impact that psychoeducation interventions have on various outcomes in children with ADHD. A systematic review of articles published between 1990 and 2018 was conducted of treatment outcome studies that investigated the effects of psychoeducation programs on youth with ADHD and their families. The outcomes of included studies consisted of ten constructs related to child and family functioning. Analyses used Hedges&#039; g formula to calculate individual study and summary effect sizes. Thirteen studies met our criteria. Among the effect sizes that were analyzed, significant findings include moderate to large effects on ADHD symptom improvement as reported by parents and teachers (g = 0. 787), parent/teacher and child knowledge about ADHD (g = 1.037 and g = 0. 721, respectively). Among the outcomes assessing child&#039;s family and social functioning, effect sizes - as reported by parents, teachers, children/adolescents, and clinicians - were moderate to small. A few outcomes, including parenting stress and quality of life, were found to have small to no effects. Overall, this systematic review found the effects of psychoeducation as an intervention led to improvement in ADHD symptoms and behavioral problems, as reported by parents - potentially as a result of parents&#039; greater knowledge about how ADHD influences their child&#039;s behavior, as well as potentially through an improvement in adherence to treatment following a psychoeducation course. Relatively few studies have looked at treatment adherence as an outcome, and this may be a future direction for researchers.
AN  - WOS:000519705300004
AU  - Dahl,
AU  - V.
AU  - Ramakrishnan,
AU  - A.
AU  - Spears,
AU  - A.
AU  - P.
AU  - Jorge,
AU  - A.
AU  - Lu,
AU  - J.
AU  - N.
AU  - Bigio,
AU  - N.
AU  - A.
AU  - Chacko,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s10882-019-09691-3
L1  - internal-pdf://1700223229/Dahl-2020.pdf
N1  - Dahl, Victoria Ramakrishnan, Amrita Spears, Angela Page Jorge, Annlady Lu, Janice Bigio, Nina Abraham Chacko, Anil1573-3580
PY  - 2020
SP  - 257-292
T2  - Journal of Developmental and Physical Disabilities
TI  - Psychoeducation Interventions for Parents and Teachers of Children and Adolescents with ADHD: a Systematic Review of the Literature
UR  - &lt;Go to ISI&gt;://WOS:000519705300004
UR  - https://link.springer.com/article/10.1007%2Fs10882-019-09691-3
UR  - https://link.springer.com/content/pdf/10.1007/s10882-019-09691-3.pdf
VL  - 32
ER  -
TY  - JOUR
AB  - **Background**
Human milk alone may provide inadequate amounts of protein to meet the growth requirements of preterm infants because of restrictions in the amount of fluid they can tolerate. It has become common practice to feed preterm infants with breast milk fortified with protein and other nutrients but there is debate about the optimal concentration of protein in commercially available fortifiers.

**Objectives**
To compare the effects of different protein concentrations in human milk fortifier, fed to preterm infants, on growth and neurodevelopment.

**Search methods**
We used the standard search strategy of Cochrane Neonatal to search CENTRAL (2019, Issue 8), Ovid MEDLINE and CINAHL on 15 August 2019. We also searched clinical trials databases and the reference lists of retrieved articles for randomised controlled trials and quasi‐randomised trials.

**Selection criteria**
We included all published and unpublished randomised, quasi‐randomised and cluster‐randomised trials comparing two different concentrations of protein in human milk fortifier.We included preterm infants (less than 37 weeks&#039; gestational age). Participants may have been exclusively fed human milk or have been supplemented with formula. The concentration of protein was classified as low (&lt; 1g protein/100 mL expressed breast milk (EBM)), moderate (&ge; 1g to &lt; 1.4g protein/100 mL EBM) or high (&ge; 1.4g protein/100 mL EBM). We excluded trials that compared two protein concentrations that fell within the same category.

**Data collection and analysis**
We undertook data collection and analyses using the standard methods of Cochrane Neonatal. Two review authors independently evaluated trials. Primary outcomes included growth, neurodevelopmental outcome and mortality. Data were synthesised using risk ratios (RR), risk differences and mean differences (MD), with 95% confidence intervals (CI). We used the GRADE approach to assess the certainty of the evidence.

**Main results**
We identified nine trials involving 861 infants. There is one trial awaiting classification, and nine ongoing trials. The trials were mostly conducted in infants born &lt; 32 weeks&#039; gestational age or &lt; 1500 g birthweight, or both. All used a fortifier derived from bovine milk. Two trials fed infants exclusively with mother&#039;s own milk, three trials gave supplementary feeds with donor human milk and four trials supplemented with preterm infant formula. Overall, trials were small but generally at low or unclear risk of bias.

High versus moderate protein concentration of human milk fortifier.

There was moderate certainty evidence that a high protein concentration likely increased in‐hospital weight gain compared to moderate concentration of human milk fortifier (MD 0.66 g/kg/day, 95% CI 0.51 to 0.82; trials = 6, participants = 606). The evidence was very uncertain about the effect of high versus moderate protein concentration on length gain (MD 0.01 cm/week, 95% CI &ndash;0.01 to 0.03; trials = 5, participants = 547; very low certainty evidence) and head circumference gain (MD 0.00 cm/week, 95% CI &ndash;0.01 to 0.02; trials = 5, participants = 549; very low certainty evidence).Only one trial reported neonatal mortality, with no deaths in either group (participants = 45). 

Moderate versus low protein concentration of human milk fortifier.

A moderate versus low protein concentration fortifier may increase weight gain (MD 2.08 g/kg/day, 95% CI 0.38 to 3.77; trials = 2, participants = 176; very low certainty evidence) with little to no effect on head circumference gain (MD 0.13 cm/week, 95% CI 0.00 to 0.26; I&sup2; = 85%; trials = 3, participants = 217; very low certainty evidence), but the evidence is very uncertain. There was low certainty evidence that a moderate protein concentration may increase length gain (MD 0.09 cm/week, 95% CI 0.05 to 0.14; trials = 3, participants = 217).

Only one trial reported mortality and found no difference between groups (RR 0.48, 95% CI 0.05 to 5.17; participants = 112). 

No trials reported long term growth or neurodevelopmental outcomes including cerebral palsy and developmental delay.

**Authors&#039; conclusions**
Feeding preterm infants with a human milk fortifier containing high amounts of protein (&ge; 1.4g/100 mL EBM) compared with a fortifier containing moderate protein concentration (&ge; 1 g to &lt; 1.4 g/100 mL EBM) results in small increases in weight gain during the neonatal admission. There may also be small increases in weight and length gain when infants are fed a fortifier containing moderate versus low protein concentration (&lt; 1 g protein/100 mL EBM). The certainty of this evidence is very low to moderate; therefore, results may change when the findings of ongoing studies are available. There is insufficient evidence to assess the impact of protein concentration on adverse effects or long term outcomes such as neurodevelopment. Further trials are needed to determine whether modest increases in weight gain observed with higher protein concentration fortifiers are associated with benefits or harms to long term growth and neurodevelopment.
AU  - Gao,
AU  - C.
AU  - Miller,
AU  - J.
AU  - Collins,
AU  - C.
AU  - T.
AU  - Rumbold,
AU  - A.
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD007090.pub2
L1  - internal-pdf://2596453748/Gao_et_al-2020-Cochrane_Database_of_Systematic.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological development in preterm infants
ER  -
TY  - JOUR
AB  - Mental disorders frequently begin in childhood or adolescence. Psychotropic medications have various indications for the treatment of mental dis-orders in this age group and are used not infrequently off-label. However, the adverse effects of these medications require special attention during developmentally sensitive periods of life. For this meta-review, we systematically searched network meta-analyses and meta-analyses of randomized controlled trials (RCTs), individual RCTs, and cohort studies reporting on 78 a priori selected adverse events across 19 categories of 80 psychotropic medications - including antidepressants, antipsychotics, anti-attention-deficit/hyperactivity disorder (ADHD) medications and mood stabilizers - in children and adolescents with mental disorders. We included data from nine network meta-analyses, 39 meta-analyses, 90 individual RCTs, and eight cohort studies, including 337,686 children and adolescents. Data on &gt;=20% of the 78 adverse events were available for six antidepressants (sertraline, escitalopram, paroxetine, fluoxetine, venlafaxine and vilazodone), eight antipsychotics (risperidone, quetiapine, aripiprazole, lurasidone, paliperidone, ziprasidone, olanzapine and asenapine), three anti-ADHD medications (methylphenidate, atomoxetine and guanfacine), and two mood stabilizers (valproate and lithium). Among these medications with data on &gt;=20% of the 78 adverse events, a safer profile emerged for escitalopram and fluoxetine among antidepressants, lurasidone for antipsychotics, methylphenidate among anti-ADHD medications, and lithium among mood stabilizers. The available literature raised most concerns about the safety of venlafaxine, olanzapine, atomoxetine, guanfacine and valproate. Nausea/vomiting and discontinuation due to adverse event were most frequently associated with antidepressants; sedation, extrapyramidal side effects, and weight gain with antipsychotics; anorexia and insomnia with anti-ADHD medications; sedation and weight gain with mood stabilizers. The results of this comprehensive and updated quantitative systematic meta-review of top-tier evidence regarding the safety of antidepressants, antipsychotics, anti-ADHD medications and mood stabilizers in children and adolescents can inform clinical practice, research and treatment guidelines.
AD  - Solmi, Marco. Neurosciences Department, University of Padua, Padua, Italy.Solmi, Marco. Padua Neuroscience Center, University of Padua, Padua, Italy.Solmi, Marco. Early Psychosis: Interventions and Clinical-detection (EPIC) lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Fornaro, Michele. Department of Psychiatry, Federico II University, Naples, Italy.Ostinelli, Edoardo G. Oxford Health NHS Foundation Trust, Warneford Hospital, and Department of Psychiatry, University of Oxford, Oxford, UK.Ostinelli, Edoardo G. Department of Health Sciences, University of Milan, Milan, Italy.Zangani, Caroline. Department of Health Sciences, University of Milan, Milan, Italy.Croatto, Giovanni. Neurosciences Department, University of Padua, Padua, Italy.Monaco, Francesco. Department of Mental Health, ASL, Salerno, Salerno, Italy.Krinitski, Damir. Integrated Psychiatry Winterthur (IPW), Winterthur, Switzerland.Fusar-Poli, Paolo. Early Psychosis: Interventions and Clinical-detection (EPIC) lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Fusar-Poli, Paolo. OASIS Service, South London &amp; Maudsley NHS Foundation Trust, London, UK.Fusar-Poli, Paolo. Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.Fusar-Poli, Paolo. National Institute for Health Research, Maudsley Biomedical Research Centre, South London &amp; Maudsley NHS Foundation Trust, London, UK.Correll, Christoph U. Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York, NY, USA.Correll, Christoph U. Department of Psychiatry and Molecular Medicine, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA.Correll, Christoph U. Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA.Correll, Christoph U. Department of Child and Adolescent Psychiatry, Charite Universitatsmedizin Berlin, Berlin, Germany.
AN  - 32394557
AU  - Solmi,
AU  - M.
AU  - Fornaro,
AU  - M.
AU  - Ostinelli,
AU  - E.
AU  - G.
AU  - Zangani,
AU  - C.
AU  - Croatto,
AU  - G.
AU  - Monaco,
AU  - F.
AU  - Krinitski,
AU  - D.
AU  - Fusar-Poli,
AU  - P.
AU  - Correll,
AU  - C.
AU  - U.
DA  - Jun
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/wps.20765
DP  - Ovid Technologies
J2  - World Psychiatry
L1  - internal-pdf://3846929622/Solmi-2020-Safety of 80 antidepressants, antip.pdf
LA  - English
N1  - Solmi, MarcoFornaro, MicheleOstinelli, Edoardo GZangani, CarolineCroatto, GiovanniMonaco, FrancescoKrinitski, DamirFusar-Poli, PaoloCorrell, Christoph U
PY  - 2020
SP  - 214-232
T2  - World Psychiatry
TI  - Safety of 80 antidepressants, antipsychotics, anti-attention-deficit/hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta-review of 78 adverse effects
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32394557
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32394557&amp;id=doi:10.1002%2Fwps.20765&amp;issn=1723-8617&amp;isbn=&amp;volume=19&amp;issue=2&amp;spage=214&amp;pages=214-232&amp;date=2020&amp;title=World+Psychiatry&amp;atitle=Safety+of+80+antidepressants%2C+antipsychotics%2C+anti-attention-deficit%2Fhyperactivity+medications+and+mood+stabilizers+in+children+and+adolescents+with+psychiatric+disorders%3A+a+large+scale+systematic+meta-review+of+78+adverse+effects.&amp;aulast=Solmi&amp;pid=%3Cauthor%3ESolmi+M%3C%2Fauthor%3E%3CAN%3E32394557%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215080/pdf/WPS-19-214.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - Academic achievement is a strong preventive factor against marginalization. Children at risk of academic failure and drop out can benefit from out-of-school-time academic (OSTA) interventions. Wide-scaled implementation and sustainment of effective interventions remain a struggle across education, welfare, and health. The need for approaches to increase implementability, effectiveness, and efficiency of interventions is pressing. Advancements in the field of education and mental health suggest identifying and studying discrete elements that are common across interventions for the purpose of hypothesis generation, intervention optimization, design improvement, and implementation. This review identified OSTA interventions for primary school children at risk of academic failure. Common elements methodology was used to code practice elements (n = 62), process elements (n = 49), and implementation elements (n = 36) in 30 effective and six ineffective OSTA interventions in matrices. Based on frequency counts, common practice, process, and implementation elements across the interventions were identified, and given frequency count values (FV) reflecting how often elements were included in effective studies as opposed to in ineffective studies. The five common practice elements with the highest FVs were homework support, training in positive parental school involvement, positive reinforcement, structured tutoring, and psychoeducation. The most common process element was regular support to intervention receiver, and the most common implementation element was quality monitoring. Common combinations of elements were also identified and given FVs. Results from this review can inform efforts to design or optimize OSTA interventions, and inform education, implementation, and practice to improve academic achievement for children at risk.
AD  - Engell, Thomas. Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway. te@r-bup.no.Engell, Thomas. Department of Psychology, University of Oslo, Oslo, Norway. te@r-bup.no.Kirkoen, Benedicte. Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway.Hammerstrom, Karianne Thune. Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway.Kornor, Hege. Norwegian Institute of Public Health, Oslo, Norway.Ludvigsen, Kristine Horseng. Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway.Hagen, Kristine Amlund. Norwegian Center for Child Behavioral Development, Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway.
AN  - 32020489
AU  - Engell,
AU  - T.
AU  - Kirkoen,
AU  - B.
AU  - Hammerstrom,
AU  - K.
AU  - T.
AU  - Kornor,
AU  - H.
AU  - Ludvigsen,
AU  - K.
AU  - H.
AU  - Hagen,
AU  - K.
AU  - A.
DA  - Feb 04
DB  - Alerts 4_2020.enl
DO  - /10.1007/s11121-020-01091-w
DP  - Ovid Technologies
J2  - Prev Sci
L1  - internal-pdf://2426082419/Engell-2020-Common Elements of Practice, Proce.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingFebEngell, ThomasKirkoen, BenedicteHammerstrom, Karianne ThuneKornor, HegeLudvigsen, Kristine HorsengHagen, Kristine Amlund
PY  - 2020
SP  - 04
T2  - Prevention Science
TI  - Common Elements of Practice, Process and Implementation in Out-of-School-Time Academic Interventions for At-risk Children: a Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32020489
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32020489&amp;id=doi:10.1007%2Fs11121-020-01091-w&amp;issn=1389-4986&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Prevention+Science&amp;atitle=Common+Elements+of+Practice%2C+Process+and+Implementation+in+Out-of-School-Time+Academic+Interventions+for+At-risk+Children%3A+a+Systematic+Review.&amp;aulast=Engell&amp;pid=%3Cauthor%3EEngell+T%3C%2Fauthor%3E%3CAN%3E32020489%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s11121-020-01091-w.pdf
VL  - 04
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering og klassifisering av behandlingsprogrammet Dialektisk atferdsterapi for ungdom (DBT-A). DBT-A er et manual- og gruppebasert tiltak på 24 ukentlige sesjoner, rettet mot ungdom i alderen 12-19 år med selvskading og tidligere selvmordsforsøk (også kalt villet egenskade). Målsetningen med DBT-A er reduksjon av denne typen atferd, samt redusert frafall fra terapi. Behandlingen består i å trene opp ferdigheter hos ungdommene i det å regulere følelser og atferd i mellommenneskelige relasjoner, og ferdigheter til å holde ut følelsesmessig smerte. Delmål i tiltaket er reduksjon i bruk av rusmidler, reduksjon av sinne og depresjon, samt generell bedring av daglig fungering.

METODE
Kunnskapsoppsummeringen bygger på et systematisk litteratursøk fra ulike databaser (Embase, Medline og Psykinfo, NORART Cochrane, Cristin, Nora, Scopus og SweMed), samt materiell fra norsk tiltakseier. Søket ble gjennomgått for å identifisere internasjonale kunnskapsoppsummeringer og nordiske effektstudier om tiltaket. Seks artikler, hvorav tre er basert på &eacute;n norsk effektstudie ble inkludert og evaluert i kunnskapsoppsummeringen.

RESULTATER
Resultatene viser at DBT-A er et kunnskaps- og evidensbasert tiltak med solid teoretisk forankring. Effektstudien (RCT) der DBT-A er sammenlignet med ordinær behandling tyder på at programmet kan bidra til redusert selvrapportert grad av selvmordstanker og selvskading for ungdom i alderen 12-18 år. Tiltaket har godt beskrevne implementeringsstrategier, noe som sannsynliggjør at tiltaket tilbys slik det er tenkt i tjenestene. De inkluderte studiene er de første effektevalueringene nasjonalt og internasjonalt.

KONKLUSJON
DBT-A klassifiseres på evidensnivå 4, dvs. som et tiltak med tilfredsstillende dokumentasjon på effekt.
AU  - Reedtz,
AU  - C.,
AU  - Wergeland,
AU  - G.,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2020
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Dialektisk atferdsterapi for ungdom (Dialectical behavior therapy for Adolescents, DBT-A)
UR  - https://ungsinn.no/post_tiltak_arkiv/dialektisk-atferdsterapi-for-ungdom-dialectical-behavior-therapy-for-adolescents-dbt-a/
VL  - 2
ER  -
TY  - JOUR
AB  - Social skills interventions are critical for promoting social, emotional, and behavioral competence for students with or at risk of emotional and behavioral disorders (EBD) and autism spectrum disorders (ASD). This single-case meta-analysis examined the effects of social skills interventions (SSIs) for students with EBD and ASD. Effect sizes were calculated for 78 cases across 25 included studies using a nonparametric effect size, Baseline Corrected Tau. The overall weighted mean effect size of 0.54 suggested a moderate effect across the 25 studies. The overall weighted mean effects for studies reporting maintenance and generalization data were 0.68 and 0.37, respectively. Potential moderators examined (disability, intervention design, intervention delivery, methodological quality) were not significant. As such, they did not moderate the outcomes for participants. We conducted a post hoc analysis and hypothesized that between-study differences may be more meaningful than the similarities shared by participants in the same moderator groups. Implications are discussed on using SSIs to address the social, emotional, and behavioral challenges of students with or at risk of EBD and ASD. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - Bowman-Perrott, Lisa: lbperrott@tamu.eduBowman-Perrott, Lisa: Texas A&amp;M University, 4225 TAMU, College Station, TX, US, 77843-4225, lbperrott@tamu.eduHutchins, Nancy S.: Diversity and Inclusion for the Mays Business School, Texas A&amp;M University, College Station, TX, USBurke, Mack D.: Department of Educational Psychology, Special Education Division, Texas A&amp;M University, College Station, TX, USBowman-Perrott, Lisa: Department of Educational Psychology, Special Education Division, Texas A&amp;M University, College Station, TX, USTarlow, Kevin R.: Hampton University, Hampton, VA, USHatton, Heather: Department of Special Education, University of Missouri, Columbia, MO, US
AN  - 2020-48255-007
AU  - Hutchins,
AU  - Nancy
AU  - S.
AU  - Burke,
AU  - Mack
AU  - D.
AU  - Bowman-Perrott,
AU  - Lisa
AU  - Tarlow,
AU  - Kevin
AU  - R.
AU  - Hatton,
AU  - Heather
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/0145445519846817
DP  - Ovid Technologies
KW  - meta-analysis, social skills, challenging behavior, autism, emotional and behavioral disorders
KW  - *At Risk Populations
KW  - *Autism Spectrum Disorders
KW  - *School Based Intervention
KW  - *Social Skills
KW  - *Emotional and Behavioral Disorders
KW  - Developmental Disorders &amp; Autism [3250]
KW  - Curriculum &amp; Programs &amp; Teaching Methods [3530]
KW  - Human
L1  - internal-pdf://0784232026/Hutchins-2020.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
SP  - 773-794
T2  - Behavior Modification
TI  - The effects of social skills interventions for students with EBD and ASD: A single-case meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-48255-007
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F0145445519846817&amp;issn=0145-4455&amp;isbn=&amp;volume=44&amp;issue=5&amp;spage=773&amp;pages=773-794&amp;date=2020&amp;title=Behavior+Modification&amp;atitle=The+effects+of+social+skills+interventions+for+students+with+EBD+and+ASD%3A+A+single-case+meta-analysis.&amp;aulast=Hutchins&amp;pid=%3Cauthor%3EHutchins%2C+Nancy+S%3C%2Fauthor%3E%3CAN%3E2020-48255-007%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/10.1177/0145445519846817?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0145445519846817
VL  - 44
ER  -
TY  - JOUR
AB  - OBJECTIVE: To verify whether early intervention focused on the family improves the cognitive, motor, and language development of children born preterm and/or at social risk in the first 3 years of life.

SOURCE OF DATA: Meta-analysis of clinical trials published between 2008 and 2018, in the following databases: CINAHL, MEDLINE - PubMed, MEDLINE - BVS, LILACS - BVS, IBECS - BVS, PEDro and Cochrane Reviews. Experimental studies on early interventions focused on the family, whose target groups were children born preterm and/or at social risk, with assessment of cognitive and/or motor and/or language development up to 3 years were included. The studies were rated using the PEDro Scale.

DATA SYNTHESIS: Twelve studies were included from a total of 3378 articles. Early intervention focused on the family contributed to the development of the cognitive (Standardized Mean Difference - SMD=0.48, 95% CI: 0.34-0.61) and motor (SMD=0.76, 95% CI: 0.55-0.96) domains of preterm infants. Regarding cognitive development, performance improvement was observed at 12, 24 and 36 months, while in the motor domain, the effect was observed only at 12 months in preterm infants. There was no benefit of the intervention in the cognitive, motor, and language outcomes of children with the social risk factor associated to biological risk.

CONCLUSION: Early intervention focused on the family has a positive effect on the cognition of preterm infants. The effect on motor development was lower, possibly due to the emphasis on interventions in family-child interaction. The effect of interventions on the development of children at social risk and on the language domain was inconclusive, due to the scarcity of studies in the area.
AD  - Ferreira, Rachel de Carvalho. Grupo Universidade Brasil, Faculdade Santa Luzia, Departamento de Fisioterapia, Santa Luzia, MG, Brazil. Electronic address: rcffisio2016@gmail.com.Alves, Claudia Regina Lindgren. Universidade Federal de Minas Gerais (UFMG), Faculdade de Medicina, Departamento de Pediatria, Belo Horizonte, MG, Brazil.Guimaraes, Marina Aguiar Pires. Universidade Federal de Minas Gerais (UFMG), Programa de Pos-Graduacao em Ciencias da Saude - Saude da Crianca e do Adolescente, Belo Horizonte, MG, Brazil.Menezes, Kenia Kiefer Parreiras de. Universidade Federal de Minas Gerais (UFMG), Escola Educacao Fisica, Fisioterapia e Terapia Ocupacional (EEFFTO), Departamento de Fisioterapia, Belo Horizonte, MG, Brazil.Magalhaes, Livia de Castro. Universidade Federal de Minas Gerais (UFMG), Escola Educacao Fisica, Fisioterapia e Terapia Ocupacional (EEFFTO), Departamento de Terapia Ocupacional, Belo Horizonte, MG, Brazil.
AN  - 31254528
AU  - Ferreira,
AU  - R.
AU  - C.
AU  - Alves,
AU  - C.
AU  - R.
AU  - L.
AU  - Guimaraes,
AU  - M.
AU  - A.
AU  - P.
AU  - Menezes,
AU  - K.
AU  - K.
AU  - P.
AU  - Magalhaes,
AU  - L.
AU  - C.
DA  - Jan - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jped.2019.05.002
DP  - Ovid Technologies
J2  - J Pediatr (Rio J)
KW  - Child
KW  - Early Intervention, Educational
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - *Infant, Premature
KW  - Language Development
L1  - internal-pdf://2667203562/Ferreira-2020.pdf
LA  - English
M3  - Review
N1  - Ferreira, Rachel de CarvalhoAlves, Claudia Regina LindgrenGuimaraes, Marina Aguiar PiresMenezes, Kenia Kiefer Parreiras deMagalhaes, Livia de CastroS0021-7557(18)31161-6
PY  - 2020
SP  - 20-38
T2  - Jornal de Pediatria
TI  - Effects of early interventions focused on the family in the development of children born preterm and/or at social risk: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=31254528
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31254528&amp;id=doi:10.1016%2Fj.jped.2019.05.002&amp;issn=0021-7557&amp;isbn=&amp;volume=96&amp;issue=1&amp;spage=20&amp;pages=20-38&amp;date=2020&amp;title=Jornal+de+Pediatria&amp;atitle=Effects+of+early+interventions+focused+on+the+family+in+the+development+of+children+born+preterm+and%2For+at+social+risk%3A+a+meta-analysis.&amp;aulast=Ferreira&amp;pid=%3Cauthor%3EFerreira+RC%3C%2Fauthor%3E%3CAN%3E31254528%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 96
ER  -
TY  - JOUR
AB  - BAKGRUNN
Circle of security (COS), eller Trygghetssirkelen på norsk, er en gruppe intervensjoner utviklet for å fremme god tilknytning mellom foreldre og barn. Intervensjonene retter seg primært mot foreldrenes evne til å forstå barnets grunnleggende behov for trygghet, tilhørighet og autonomi slik at barnets trygghetsfølelse og selvforståelse øker.

Denne artikkelen beskriver Circle of Security (COS) Virginia &ndash; Familiemodellen (COS-VF), som er en terapeutisk intervensjon rettet mot enkelt-familier. Tiltaket kan brukes når barn har utviklet, eller er i risiko for å utvikle, tilknytningsproblematikk. Tiltaket driftes av Regionsenter for barn og unges psykiske helse Øst og Sør (RBUP Øst og Sør).

METODE
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens, samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

RESULTATER
Resultatene består av en vurdering av tiltakets beskrivelse, foreliggende studier og implementeringskvalitet. COS-VF vurderes som et tilfredsstillende beskrevet tiltak med en god teoretisk forankring. Det finnes derimot ingen nordiske studier eller internasjonale kunnskapsoppsummeringer der effektene av tiltaket er undersøkt. Dette innebærer at det er usikkert hvilken virkning tiltaket faktisk har med tanke på å kunne forbedre samspillsmønstre og fremme trygg tilknytning. Tiltaket har en god implementeringsstrategi som sannsynliggjør at tiltaket tilbys slik det er tenkt i tjenestene.

KONKLUSJON
COS-VF klassifiseres på evidensnivå 2 &ndash; Teoretisk begrunnede tiltak.
AU  - Eng,
AU  - H.,
AU  - Rye,
AU  - M.,
AU  - Ulvund,
AU  - S.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2020
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Circle of Security Virginia - Familiemodellen (COS-VF, 2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/circle-of-security-virginia-familiemodellen-cos-vf-2-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - BAKGRUNN
Telemarksmodellen er en kursrekke utviklet for å fremme psykisk helse og forebygge sosiale vansker for barn som har forståelsesvansker i form av en lett psykisk utviklingshemming. Kursene gis når barnet går på mellomtrinnet i barneskole, ungdomstrinnet og i videregående skole. Formen er psykoedukativ hvor en veksler mellom informasjon, råd, veiledning og samtale om et hverdagsliv med forståelsesvansker. En slik terapeutisk kunnskapsformidling og møte med andre i samme situasjon, ansees å bidra til økt mestring og kompetanse.

Denne artikkelen beskriver Telemarksmodellen. Det er et tiltak som tilbys barn som får diagnosen lett psykisk utviklingshemming og deres foresatte. Tiltaket gis i etterkant av diagnostisk utredning i Habilitering for barn og unge (HABU) i Sykehuset Telemark. Kursrekken gis i separate grupper hvor barna, ungdommene og foresatte har hvert sitt kursprogram. Tema i kursene er knyttet til aktuelle livsfaser og omhandler kropp, hygiene, fritid, vennskap, pubertet, seksuell helse, arbeid og hjelpestønader. Tiltaket er utviklet av og driftes av HABU Sykehuset Telemark.

METODE
Denne gjennomgangen er basert på tilsendt informasjon fra utvikleren av Telemarksmodellen, i tillegg til litteratursøk etter studier om tiltaket. Søket ble gjennomført i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Google Scholar, Cristin, NORA, Norart, SCOPUS, SweMed+, Cambell, NREPP, NICE, Blueprint, Helsebiblioteket.no, CEBC, Vidensportalen, Metodeguiden og CINAHL plus with Full Text.

RESULTATER
Resultatene består av en vurdering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Det ble ikke identifisert noen studier som har undersøkt effekt eller evalueringer av Telemarksmodellen. I materialet som foreligger fremstår ikke Telemarksmodellen å være beskrevet for å gi ekstern opplæring i metoden. Tiltaket virker kun å være gjennomført ved Sykehuset Telemark. Det foreligger ingen implementeringsplaner og derfor heller ikke noen beskrevet implementeringsstrategi.

KONKLUSJON
Basert på Ungsinn sine kriterier klassifiseres Telemarksmodellen på evidensnivå 1- godt beskrevne tiltak.
AU  - Halvorsen,
AU  - M.,
AU  - Rustad,
AU  - K.
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2020
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Telemarksmodellen: Vegen blir til mens vi går den sammen (1.utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/telemarksmodellen-vegen-blir-til-mens-vi-gar-den-sammen/
VL  - 2
ER  -
TY  - JOUR
AB  - **Introduction:** 
The health benefits of physical activity have gained interest as an intervention tool for mental health. The primary aim of this systematic review and meta-analysis was to determine the effects of interventions with physical activity components on measures of anxiety, depression and stress in young people. 

**Method(s):** 
A systematic search was carried out across nine electronic databases (MEDLINE, CINAHL, ERIC, British Education Index, Child Development and Adolescent Studies, CENTRAL, Embase, SportDiscus and Psychinfo). Inclusion criteria were studies that used physical activity components with anxiety, depression and stress outcomes in a target population aged 10-19 years. Intervention effects (mean differences) were calculated with a random-effects model. A risk of bias assessment was conducted. 

**Result(s):**
A total of 13 studies depicting 11 RCT and 2 Cluster RCT&#039;s with 1928 participants were included. 11 studies were eligible for meta-analyses. The meta-analyses for anxiety demonstrated no difference between groups at follow-up (SMD 0.04; 95% CI -0.20, 0.28; I&lt;sup&gt;2&lt;/sup&gt; = 55%) or when measured as change from baseline (SMD -0.33; 95% CI -0.68, 0.03; I&lt;sup&gt;2&lt;/sup&gt; = 0%). Similarly, no difference in depression was demonstrated between groups at follow-up (SMD 0.09; 95% CI -0.20, 0.40; I&lt;sup&gt;2&lt;/sup&gt; = 72%) or when measured as change from baseline (SMD -0.11; 95% CI -0.29, 0.07; I&lt;sup&gt;2&lt;/sup&gt; = 0%). The meta-analyses showed no overall affect and included studies had high risk of bias and heterogeneity therefore results should be viewed tentatively. 

**Conclusion(s):** 
The ability of physical activity components within interventions to produce meaningful change in anxiety, depression and stress outcomes in adolescents remains unclear as the results of the meta-analyses showed no overall affect. Therefore more conclusive studies should be conducted in the future. Copyright &copy; 2020 Elsevier Ltd
AD  - (Neill, Lloyd, Best) School of Social Sciences, Education and Social Work, Queen&#039;s University Belfast, Belfast, Northern Ireland, United Kingdom (Tully) School of Health Sciences, Institute of Mental Health Sciences, Ulster University, Jordanstown Campus, Newtownabbey, Northern Ireland, United KingdomR.D. Neill, School of Social Sciences, Education and Social Work, Queens University Belfast, 20 College Green, United Kingdom. E-mail: rneill14@qub.ac.uk
AN  - 2007969027
AU  - Neill,
AU  - R.
AU  - D.
AU  - Lloyd,
AU  - K.
AU  - Best,
AU  - P.
AU  - Tully,
AU  - M.
AU  - A.
DA  - October
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.mhpa.2020.100359
DP  - Ovid Technologies
KW  - Adolescent mental health
KW  - Anxiety
KW  - Depression
KW  - Stress
KW  - adolescent
KW  - child
KW  - child development
KW  - Cinahl
KW  - education
KW  - Embase
KW  - female
KW  - follow up
KW  - human
KW  - male
KW  - Medline
KW  - mental health
KW  - meta analysis
KW  - physical activity
KW  - PsycINFO
KW  - review
KW  - risk assessment
KW  - school child
KW  - systematic review
L1  - internal-pdf://2378293620/Neill-2020.pdf
LA  - English
M3  - Review
PY  - 2020
T2  - Mental Health and Physical Activity
TI  - The effects of interventions with physical activity components on adolescent mental health: Systematic review and meta-analysis
UR  - http://www.elsevier.com
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2007969027
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.mhpa.2020.100359&amp;issn=1755-2966&amp;isbn=&amp;volume=19&amp;issue=&amp;spage=100359&amp;pages=&amp;date=2020&amp;title=Mental+Health+and+Physical+Activity&amp;atitle=The+effects+of+interventions+with+physical+activity+components+on+adolescent+mental+health%3A+Systematic+review+and+meta-analysis&amp;aulast=Neill&amp;pid=%3Cauthor%3ENeill+R.D.%3C%2Fauthor%3E%3CAN%3E2007969027%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/abs/pii/S1755296620300430?via%3Dihub
VL  - 19 (no pagination)
ER  -
TY  - JOUR
AB  - BAKGRUNN
Circle of Security (COS), eller Trygghetssirkelen på norsk, er en gruppe intervensjoner utviklet for å fremme god tilknytning mellom foreldre og barn. Intervensjonene retter seg primært mot foreldrenes evne til å forstå barnets grunnleggende behov for trygghet, tilhørighet og autonomi slik at barnets trygghetsfølelse og selvforståelse øker. Denne kunnskapsoppsummeringen beskriver Circle of Security Virginia &ndash; Gruppemodellen (COS-VG), som er en forebyggende gruppeintervensjon rettet mot foreldre. Tiltaket kan tilbys familier med barn i mild til moderat risiko for å utvikle tilknytningsproblematikk. Tiltaket har inntil nylig blitt driftet av Regionsenter for barn og unges psykiske helse Øst og Sør (RBUP Øst og Sør). På grunn av manglende forskningsbelegg og fravær av forskningsmidler tilbyr RBUP Øst og Sør ikke lenger opplæring i COS-VG.

METODE
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS, CINAHL og SweMed. Det er også søkt i internasjonale kunnskapsdatabaser om evidens samt innhentet informasjon om tiltaket fra tiltakseier. Litteratursøk og annen innhentet informasjon ble gjennomgått for å identifisere nordiske effektstudier, internasjonale oppsummeringsstudier og eventuelt andre norske studier om tiltaket.

RESULTATER
Resultatene består av en vurdering av tiltakets beskrivelse, foreliggende studier og implementeringskvalitet. COS-VG vurderes som godt beskrevet tiltak med en god teoretisk forankring. Det finnes derimot ingen nordiske studier eller internasjonale kunnskapsoppsummeringer som har undersøkt effekten av tiltaket. Det er dermed usikker hvilken virkning tiltaket faktisk har med tanke på å kunne fremme trygg tilknytning.

KONKLUSJON
COS-VG klassifiseres på evidensnivå 2 &ndash; Teoretisk begrunnet tiltak.
AU  - Rye,
AU  - M.,
AU  - Eng,
AU  - H.,
AU  - Ulvund,
AU  - S.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2020
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Circle of Security Virginia &ndash; Gruppemodellen (COS-VG) (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/circle-of-security-virginia-gruppemodellen-cos-vg-2-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - **Background**
The aim of this study was to review the effects of developmental care in neonatal intensive care unit (NICU) setting on mental and motor development of preterm infants. 

**Method** 
We searched PubMed, EMBASE, CINAHL, Scopus, Web of Science and Cochrane library until October 8th 2017, and included randomized controlled trials that assessed effects of developmental care in NICU on mental and motor development of preterm infants at 12 and 24 months of age, using the Bayley scale of infant development in this systematic review. In addition, data were pooled by random effects model and Standardized Mean Difference (SMD) with 95% confidence intervals (CI), calculated for meta-analysis. 

**Results** 
Twenty one studies were eligible to be included in this systematic review; however, only thirteen studies had data suitable for meta-analysis. According to statistical analysis, developmental care in NICU improved mental developmental index (MDI) (standardized mean difference [SMD] 0.55, 95% confidence interval [CI] 0.23-0.87; p &lt; 0.05), and psychomotor developmental index (PDI) (SMD 0.33, [CI] 95% CI 0.08-0.57; p &lt; 0.05) of BSID at 12 months of age and PDI at 24 months of age (SMD 0.15, 95% CI -0.02-0.32; p &lt; 0.1) of preterm infants. However, the benefit was not detected at 24 months of age on MDI (SMD 0.15, 95% CI -0.05-0.35; p = 0.15). 

**Conclusion** 
Current evidence suggests that developmental care in only NICU setting could have significant effect on mental and motor development of preterm infants, especially at 12 months of age. However, because of clinical heterogeneity, more studies are needed to evaluate the effects of developmental NICU care in the development of preterm infants.
AD  - [Soleimani, Farin; Azari, Nadia; Ghiasvand, Hesam; Shahrokhi, Amin; Fatollahierad, Shiva] Univ Social Welf &amp; Rehabil Sci, Pediat Neurorehabil Res Ctr, Tehran, Iran. [Ghiasvand, Hesam] Univ Exeter, Med Sch, Inst Hlth Res, Hlth Econ Grp, St Lukes Campus, Exeter, Devon, England. [Rahmani, Nahid] Univ Social Welf &amp; Rehabil Sci, Pediat Neurorehabil Res Ctr, Dept Physiotherapy, Tehran, Iran.Fatollahierad, S (reprint author), Univ Social Welf &amp; Rehabil Sci, Pediat Neurorehabil Res Ctr, Tehran, Iran.sh.fatollahie.rad@gmail.com
AN  - WOS:000514915000001
AU  - Soleimani,
AU  - F.
AU  - Azari,
AU  - N.
AU  - Ghiasvand,
AU  - H.
AU  - Shahrokhi,
AU  - A.
AU  - Rahmani,
AU  - N.
AU  - Fatollahierad,
AU  - S.
DA  - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1186/s12887-020-1953-1
J2  - BMC Pediatr.
KW  - Preterm infants
KW  - Developmental care
KW  - NICU
KW  - Interventions
KW  - Bayley scales
KW  - of infant development
KW  - Meta-analysis
KW  - Systematic review
KW  - birth-weight infants
KW  - long-term outcomes
KW  - early intervention
KW  - follow-up
KW  - premature-infants
KW  - assessment program
KW  - brain-function
KW  - cycled light
KW  - unit
KW  - stimulation
KW  - Pediatrics
L1  - internal-pdf://1316728864/Soleimani-2020-Do NICU developmental care impr.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: KN5ZHTimes Cited: 0Cited Reference Count: 65Soleimani, Farin Azari, Nadia Ghiasvand, Hesam Shahrokhi, Amin Rahmani, Nahid Fatollahierad, ShivaUniversity of Social Welfare and Rehabilitation SciencesThis work was supported by the University of Social Welfare and Rehabilitation Sciences. The funders had no role in the design, data collection, analysis of the study, nor the decision to publish or the preparation of this manuscript.0BmcLondon1471-2431
PY  - 2020
SP  - 16
T2  - Bmc Pediatrics
TI  - Do NICU developmental care improve cognitive and motor outcomes for preterm infants? A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000514915000001
UR  - https://bmcpediatr.biomedcentral.com/track/pdf/10.1186/s12887-020-1953-1
VL  - 20
ER  -
TY  - JOUR
AB  - **Slutsatser**
SBU har gjort en syste&shy;matisk &shy;&ouml;versikt av psyko&shy;sociala &ouml;ppenvårdsinsatser f&ouml;r att f&ouml;re&shy;bygga återfall i brott bland ung&shy;domar som &auml;r 12&ndash;17 år. Syftet har varit att ta fram ett veten&shy;skapligt underlag f&ouml;r kom&shy;mande kunskaps&shy;st&ouml;d från Socialstyrelsen. SBU:s slutsatser &auml;r f&ouml;ljande:

Utifrån de granskade studierna går det inte att avg&ouml;ra vilka specifika psyko&shy;sociala &ouml;ppen&shy;vårds&shy;insatser som &auml;r mer effek&shy;tiva &auml;n det de j&auml;mf&ouml;rts med n&auml;r det g&auml;ller åter&shy;fall i brott de f&ouml;ljande åren (i genom&shy;snitt två år) (Mycket låg tillf&ouml;rlitlighet).

Att det saknas s&auml;ker kunskap om vilka effekter som olika specifika psyko&shy;sociala &ouml;ppen&shy;vårds&shy;insatser kan ha på ungdomars återfall i brott inneb&auml;r inte att social&shy;tj&auml;nsten och barn- och ungdoms&shy;psykiatrin per auto&shy;matik ska sluta att anv&auml;nda dem. Det kan &auml;ven anses som etiskt proble&shy;matiskt att avstå från insatser som teore&shy;tiskt skulle kunna f&ouml;re&shy;bygga brott, och som upplevs fungera v&auml;l av verk&shy;samheter och klienter.

SBU:s praxis&shy;under&shy;s&ouml;kning visar att svensk social&shy;tj&auml;nst och barn- och ungdoms&shy;psykiatri anv&auml;nder ett stort antal &ouml;ppen&shy;vård&shy;sinsatser f&ouml;r unga som begått brott. Många av insat&shy;serna saknar manual och har inte utv&auml;rde&shy;rats i fråga om att f&ouml;rhindra nya brott.

**Syfte**
Syftet med projektet var att syste&shy;matiskt utv&auml;rdera det veten&shy;skapliga st&ouml;det f&ouml;r psyko&shy;sociala insatser inom social&shy;tj&auml;nstens och barn- och ungdoms&shy;psykiatrins &ouml;ppen&shy;vård f&ouml;r att f&ouml;re&shy;bygga ungdomars återfall i brott.

**Metod**
Denna syste&shy;matiska utv&auml;rdering omfattar fyra delar; a) en utv&auml;rde&shy;ring av effekter av psyko&shy;sociala &ouml;ppen&shy;vård&shy;sinsatser f&ouml;r unga som har begått brott b) en ber&auml;kning av kost&shy;nader f&ouml;r r&auml;tts&shy;process och påf&ouml;ljder f&ouml;r brott begångna av unga c) ett kapitel d&auml;r etiska aspekter diskuteras samt d) en praxis&shy;under&shy;s&ouml;kning av vilka insatser som idag anv&auml;nds inom social&shy;tj&auml;nst samt barn- och ungdoms&shy;psykiatrisk &ouml;ppen&shy;vård. &Ouml;ppen&shy;vård&shy;sinsat&shy;serna som utv&auml;r&shy;deras ges till ungdomar (12&ndash;17 år) som har begått brott. De ska kunna genom&shy;f&ouml;ras indivi&shy;duellt eller i grupp. Studierna ska innehålla en j&auml;mf&ouml;relse&shy;grupp, ha minst sex månaders upp&shy;f&ouml;lj&shy;nings&shy;tid efter avslutad insats, eller 18 månader efter start, samt vara genom&shy;f&ouml;rda med tillr&auml;ck&shy;ligt god kvalitet. F&ouml;ljande 19 &ouml;ppen&shy;vårds&shy;insatser utv&auml;rde&shy;rades i studier som uppfyllde &ouml;ver&shy;siktens kriterier och inklude&shy;rades d&auml;rmed i &ouml;ver&shy;sikten: Aggres&shy;sion replace&shy;ment training (ART), kort inter&shy;vention med f&auml;rdighets&shy;tr&auml;ning, Family empower&shy;ment inter&shy;vention, Funk&shy;tionell familje&shy;terapi (FFT), indivi&shy;duellt behand&shy;lings&shy;program f&ouml;r unga snattare, ISSP multi&shy;syste&shy;misk inter&shy;vention, kognitiv beteende&shy;terapi (KBT) i grupp, medling, mentor&shy;skap, Multi&shy;dimen&shy;sionell familje&shy;terapi (MDFT), Multi&shy;systemisk terapi (MST), New perspective &ndash; coachning, psyko&shy;edukativ counselling i grupp, PHAT life &ndash; psyko&shy;social grupp&shy;inter&shy;vention, Ottawa Community youth diversion program, the SafERteens brief intervention, Step up &ndash; grupp&shy;insats f&ouml;r hela familjen, Team case management, samt yrkes&shy;program inom bygg&shy;branschen.

**Resultat**

Frågest&auml;llning 1: Vilka effekter har psyko&shy;sociala insatser som kan genom&shy;f&ouml;ras i &ouml;ppen&shy;vård f&ouml;r ungdomar som begått brott?

Utifrån de granskade studierna går det inte att avg&ouml;ra vilka speci&shy;fika psyko&shy;sociala &ouml;ppen&shy;vårds&shy;insatser som &auml;r mer effektiva &auml;n andra n&auml;r det g&auml;ller återfall i brott under i genom&shy;snitt två år. Vi vet alltså inte om de under&shy;s&ouml;kta &ouml;ppen&shy;vårds&shy;insat&shy;serna &auml;r b&auml;ttre &auml;n, likv&auml;rdiga med eller s&auml;mre &auml;n det de j&auml;mf&ouml;rs med. Upp&shy;f&ouml;lj&shy;nings&shy;tiden i de olika studierna varierade mellan 1 och 21 år. Två tredjedelar av samt&shy;liga ungdomar i de inklude&shy;rade studierna hade inte åter&shy;fallit i brott vid upp&shy;f&ouml;lj&shy;ning efter i genom&shy;snitt två år.

Kompletterande analyser av samt&shy;liga insatser samman&shy;slagna visade att inne&shy;hållet i j&auml;mf&ouml;relse&shy;insatsen spelade roll f&ouml;r hur starka effekterna blev; skillnaden i effekt var st&ouml;rre n&auml;r j&auml;mf&ouml;relse&shy;insatsen var mindre omfattande (med f&ouml;rdel f&ouml;r den utv&auml;rde&shy;rade insatsen). Resultaten talar inte f&ouml;r att effekten på återfall i brott påverkades av deltagarnas ålder, andel pojkar, vilken studiedesign man anv&auml;nt, i vilket land studien genomf&ouml;rts, uppf&ouml;ljningstid eller publikationsår.

Frågest&auml;llning 2: Vilken &auml;r den samh&auml;lls&shy;ekono&shy;miska nyttan av insatserna i fråga om att f&ouml;rhindra ungdomars återfall i brott?

En f&ouml;ruts&auml;ttning f&ouml;r en ekono&shy;misk utv&auml;rde&shy;ring &auml;r att det finns kunskap om vilken effekt en insats har. I detta projekt har tillf&ouml;r&shy;litlig&shy;heten i det veten&shy;skapliga under&shy;laget varit mycket lågt avseende insat&shy;sernas effekter på återfall i brott. Det har d&auml;rf&ouml;r inte varit m&ouml;jligt att genom&shy;f&ouml;ra någon analys av insat&shy;sernas samh&auml;lls&shy;ekono&shy;miska nytta. Vi har genom&shy;f&ouml;rt ber&auml;k&shy;ningar av kostna&shy;derna f&ouml;r r&auml;tts&shy;process och påf&ouml;ljder som visar att en kostnad på uppskatt&shy;nings&shy;vis 2,4 miljoner kronor kan undvikas om ett brott som leder till påf&ouml;ljden sluten ungdoms&shy;vård kan f&ouml;rhindras.

Frågest&auml;llning 3: Vilka etiska aspekter &auml;r viktiga att beakta n&auml;r det g&auml;ller insatser f&ouml;r att f&ouml;re&shy;bygga ungdomars återfall i brott?

Socialtj&auml;nsten och barn- och ungdoms&shy;psykia&shy;trin kan inte sluta anv&auml;nda &ouml;ppen&shy;vårds&shy;insatser f&ouml;r att de saknar veten&shy;skapligt st&ouml;d. Det beh&ouml;vs rutiner f&ouml;r att l&ouml;pande granska och doku&shy;mentera insatsers f&ouml;r- och nack&shy;delar f&ouml;r den enskilda ungdomen och att man har beredskap att vid behov byta till en eller flera alter&shy;nativa insatser. Detta f&ouml;ruts&auml;tter konti&shy;nuerlig uppf&ouml;lj&shy;ning av om f&ouml;r&auml;nd&shy;ringar sker i r&auml;tt riktning.

Frågest&auml;llning 4: Vilka insatser anv&auml;nds inom svensk social&shy;tj&auml;nst och barn- och ungdoms&shy;psykiatri f&ouml;r mål&shy;gruppen ungdomar som begått brott

Både socialtj&auml;nst och barn&shy;psykiat&shy;riska mottag&shy;ningar anv&auml;nde ett stort antal olika &ouml;ppen&shy;vårds&shy;insatser. Vanligast inom social&shy;tj&auml;nsten var ospecifi&shy;cerade st&ouml;d&shy;samtal med ungdomar respektive f&ouml;r&auml;ldrar, kontakt&shy;familj eller kontakt&shy;person samt ospecifi&shy;cerad familje&shy;behand&shy;ling eller familje&shy;terapi. Bland BUP-verksam&shy;heterna var kognitiv beteende&shy;terapi, st&ouml;dsamtal med ungdomar och l&auml;kemedel vanligt. En majori&shy;tet av de insatser som anv&auml;nds har inte pr&ouml;vats veten&shy;skapligt vad g&auml;ller återfall i brott, varken inter&shy;na&shy;tionellt eller under svenska f&ouml;rhållanden.

**Diskussion**
Enligt denna syste&shy;matiska &ouml;versikt går det inte att avg&ouml;ra om någon enskild namn&shy;given insats &auml;r mer effektiv &auml;n andra n&auml;r det g&auml;ller att f&ouml;rebygga återfall i brott. De flesta ungdomarna i studierna återf&ouml;ll dock inte i ny registrerad brottslighet de n&auml;rmast påf&ouml;ljande åren. Detta st&auml;mmer med upp&shy;gifter från Brå, de flesta tonåringar som begår brott upph&ouml;r med det vid intr&auml;dandet till vuxenlivet (år 2012 återf&ouml;ll 35 % av brottsd&ouml;mda 15&ndash;17-åringar inom två år enligt Brå.

Att vi inte med s&auml;kerhet k&auml;nner till insatsers effekter betyder inte att insatser &auml;r dåliga eller att social&shy;tj&auml;nsten eller barn- och ungdoms&shy;psykiatrin ska sluta anv&auml;nda insatser som upplevs fungera v&auml;l. N&auml;r det inte finns något veten&shy;skapligt underbyggt f&ouml;rsta&shy;hands&shy;val så blir den indi&shy;viduella vård- och genom&shy;f&ouml;rande&shy;planen s&auml;rskilt viktig. Den indi&shy;viduali&shy;serade planen beh&ouml;ver f&ouml;ljas upp regel&shy;bundet och anpassas till de aktuella f&ouml;rut&shy;s&auml;t&shy;tningarna. Det kr&auml;vs uppf&ouml;ljning, till exempel om ungdomen eller andra ber&ouml;rda (t.ex. familj/vårdnads&shy;havare) &auml;r motiverad till behand&shy;ling och om f&ouml;r&auml;nd&shy;ring sker i r&auml;tt riktning. Det beh&ouml;vs en beredskap f&ouml;r ompr&ouml;v&shy;ning n&auml;r insatserna inte ger &ouml;nskat resultat och man beh&ouml;ver fundera igenom vilka utfalls&shy;mått man vill påverka med insatsen i det enskilda fallet. Dessutom vilka risk- och skydds&shy;faktorer man beh&ouml;ver arbeta med och utv&auml;rdera. F&ouml;rutom uppf&ouml;lj&shy;ning på individ&shy;nivå beh&ouml;ver man &auml;ven f&ouml;lja upp insatserna &ouml;ver&shy;gripande från ett verksam&shy;hets&shy;pers&shy;pektiv.

Den 1 januari 2020 blev barnkonven&shy;tionen svensk lag. Enligt barnkon&shy;ven&shy;tionen har varje m&auml;nniska under 18 år, oavsett bak&shy;grund, r&auml;tt att behandlas med respekt och att få komma till tals. De grund&shy;l&auml;ggande princi&shy;perna inneb&auml;r att varje barn upp till 18 år, utan undantag, har r&auml;tt att få del av sina r&auml;ttig&shy;heter; att barnets b&auml;sta ska beaktas vid alla beslut som ber&ouml;r barn; att barnets utveckling ska s&auml;kerst&auml;llas till det yttersta av sam&shy;h&auml;llets f&ouml;rmåga; samt att barnets åsikter ska få komma fram och visas respekt. Vid planering och genom&shy;f&ouml;rande av insatser ska barnets r&auml;ttig&shy;heter enligt barnkon&shy;ventionen och annan g&auml;llande lag&shy;stiftning i Sverige beaktas. N&auml;r det g&auml;ller &ouml;ppen&shy;vårds&shy;insatser inom social&shy;tj&auml;nst eller barn- och ungdoms&shy;psykiatri kan det till exempel handla om att klienten får m&ouml;jlighet att vara med och påverka val av samt inne&shy;håll i en insats, och att få v&auml;rdera utfallet av insatsen. Detta f&ouml;ruts&auml;tter att insat&shy;sens innehåll och syfte &auml;r trans&shy;parent och kommuni&shy;ceras till klienten. Det &auml;r f&ouml;rstås &auml;ven viktigt att ta h&auml;nsyn till brottslig&shy;hetens konsek&shy;venser f&ouml;r andra personer. Finns det exem&shy;pelvis insatser som kan gynna offer eller ungdomens familj?

Det finns ingenting i studierna som tyder på att de utv&auml;rderade insat&shy;serna skulle vara skadliga, till exempel &ouml;ka brotts&shy;ligheten. D&auml;remot finns det tidigare forsk&shy;ning som visat att så kallade avskr&auml;ckande insatser (eng. scared straight) kan leda till &ouml;kad brotts&shy;lighet hos unga som har begått brott.

Vi vet inte hur de utv&auml;rderade insatsernas effekti&shy;vitet skulle falla ut om de j&auml;mf&ouml;rdes med de standard&shy;insatser som ges i Sverige idag. Praxis&shy;under&shy;s&ouml;k&shy;ningen från 2019 visar att de vanligaste insat&shy;serna i Sverige (st&ouml;d&shy;samtal, kontakt&shy;familj) har oklar struktur och inte &auml;r manual&shy;baserade. I j&auml;mf&ouml;relse med denna typ av insatser kan man speku&shy;lera i om effekterna av de manual&shy;baserade insat&shy;serna som unders&ouml;kts i denna &ouml;versikt skulle bli starkare. Analyser på samt&shy;liga insatser samman&shy;slagna visade att skill&shy;naden i effekten på återfall i brott var st&ouml;rre n&auml;r j&auml;mf&ouml;relse&shy;insatsen var mindre omfattande (med f&ouml;rdel f&ouml;r den utv&auml;rde&shy;rade insatsen).

Det b&ouml;r &auml;ven noteras att de insatser som har inklu&shy;derats i denna &ouml;ver&shy;sikt kan vara utv&auml;rderade f&ouml;r andra mål&shy;grupper eller utfalls&shy;mått. Till exempel finns Multi&shy;syste&shy;misk terapi (MST) och Multi&shy;dimen&shy;sionell familje&shy;terapi (MDFT) med i Socialstyrelsens natio&shy;nella rikt&shy;linjer om missbruk och beroende av alkohol och narko&shy;tika f&ouml;r ungdomar under 18 år (Socialstyrelsen Artikelnummer 2019-1-16).

Resultaten från denna &ouml;versikt &ouml;verens&shy;st&auml;mmer med tidigare forskning, som visar att skill&shy;naderna mellan olika specifika &ouml;ppen&shy;vårds&shy;insatser f&ouml;r unga som begått brott var små, n&auml;r det g&auml;ller hur stor andel som åter&shy;faller i brott [17]. Skill&shy;nader i resultat mellan olika studier skulle ist&auml;llet kunna f&ouml;rklaras med faktorer som; att ung&shy;domarna i studierna har olika krimina&shy;litets- eller risk&shy;nivå, olika forsk&shy;nings&shy;metodik samt hur v&auml;l man implemen&shy;terat insat&shy;serna. Resul&shy;taten i SBU:s rapport kunde inte påvisa att forsk&shy;nings&shy;metodik (dvs. randomi&shy;serade eller icke-randomi&shy;serade studier) påverkade observerade effekter på återfall i brott. Fler studier skulle beh&ouml;vas f&ouml;r att se tydliga m&ouml;nster, &auml;ven n&auml;r det g&auml;ller ungdomars krimi&shy;nalitet- eller risknivå. Informa&shy;tion om omfattning och kvalitet på implemen&shy;tering saknades enligt vår bed&ouml;m&shy;ning i de flesta av studierna. Andra moderatorer som andel pojkar, ålder, uppf&ouml;lj&shy;nings&shy;tid samt vilket år studierna publicerats resul&shy;terade inte i statis&shy;tiskt s&auml;ker&shy;st&auml;llda skillnader n&auml;r det g&auml;ller insatsers effekter på återfall i brott.

Ny forskning b&ouml;r ta h&auml;nsyn till vilka studier med en god teorimodell och genomf&ouml;rbarhet samt lovande resultat som redan publi&shy;cerats, och &ouml;ver&shy;v&auml;ga upprep&shy;ning av dessa f&ouml;r att s&auml;krare kunna bed&ouml;ma insatsers effekter. En annan viktig aspekt som b&ouml;r g&ouml;ras &auml;r en tydlig beskriv&shy;ning av vad som ingår i den j&auml;m&shy;f&ouml;rande insatsen.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /sv/publikationer/SBU-utvarderar/insatser-i-oppenvard-for-att-forebygga-ungdomars-aterfall-i-brott/
PY  - 2020
TI  - Insatser i &ouml;ppenvård f&ouml;r att f&ouml;rebygga ungdomars återfall i brott. En systematisk &ouml;versikt och utv&auml;rdering av ekonomiska, sociala och etiska aspekter.
ER  -
TY  - JOUR
AB  - Barn och unga i Sverige som v&auml;xer upp i familjehem eller i hem f&ouml;r vård eller boende (HVB) har kraftiga &ouml;verrisker i en rad o&ouml;nskade tillstånd som vuxna såsom heml&ouml;shet, arbetsl&ouml;shet, bristande f&ouml;rs&ouml;rjningsf&ouml;rmåga, fysiska och psykiska problem och kontakt med straffr&auml;ttssystemet.

SBU har gjort en systematisk &ouml;versikt om huruvida st&ouml;d till unga som ska flytta från social dygnsvård kan underl&auml;tta deras &ouml;vergång till ett sj&auml;lvst&auml;ndigt liv.

Syftet med denna systematiska &ouml;versikt &auml;r att unders&ouml;ka om st&ouml;d till unga som flyttar från social dygnsvård har positiva effekter på deras framtida livssituation.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DA  - September
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /sv/publikationer/sbu-bereder/stod-till-unga-som-ska-flytta-fran-placering-i-social-dygnsvard/
L1  - internal-pdf://0278733492/stod-till-unga-som-ska-flytta-fran-placering-i.pdf
PY  - 2020
TI  - St&ouml;d till unga som ska flytta från placering i social dygnsvård
ER  -
TY  - JOUR
AB  - Child maltreatment is associated with elevated risk of post-traumatic stress disorder (PTSD), which can often present alongside comorbidities. While evidence-based treatments for PTSD in young people already exist, there remains ongoing clinical and academic debate about the suitability of these approaches, particularly cognitive-behavioral approaches, for young people who have been exposed to more complex traumatic experiences, such as maltreatment. We conducted an updated systematic review of the evidence-base for psychological treatments for PTSD, specifically for maltreated young people. Fifteen randomized controlled trials and five non-randomized controlled clinical trials satisfied the inclusion criteria. Trials included treatments ranging from trauma-focused CBT to creative-based therapies. Trauma-focused CBT remained the best supported treatment for children and adolescents following child maltreatment, with new evidence that symptom improvements are maintained at longer-term follow up. The evidence for other therapies remained limited, and there were concerns regarding methodological quality. Implications for treatment decision-making are discussed.
AD  - Bennett, Rhiannon S. Department of Psychology, University of Bath, United Kingdom.Bennett, Rhiannon S. Avon &amp; Wiltshire Mental Health Partnership NHS Trust, United Kingdom.Denne, Megan. Department of Psychology, University of Bath, United Kingdom.McGuire, Rosie. Department of Psychology, University of Bath, United Kingdom.Hiller, Rachel M. Department of Psychology, University of Bath, United Kingdom.
AN  - 33016112
AU  - Bennett,
AU  - R.
AU  - S.
AU  - Denne,
AU  - M.
AU  - McGuire,
AU  - R.
AU  - Hiller,
AU  - R.
AU  - M.
DA  - Oct 05
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1077559520961176
DP  - Ovid Technologies
J2  - Child Maltreat
L1  - internal-pdf://0332504344/Bennett-2020.pdf
LA  - English
N1  - Bennett, Rhiannon SDenne, MeganMcGuire, RosieHiller, Rachel M
PY  - 2020
SP  - 1077559520961176
T2  - Child Maltreatment
TI  - A Systematic Review of Controlled-Trials for PTSD in Maltreated Children and Adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33016112
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33016112&amp;id=doi:10.1177%2F1077559520961176&amp;issn=1077-5595&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1077559520961176&amp;pages=1077559520961176&amp;date=2020&amp;title=Child+Maltreatment&amp;atitle=A+Systematic+Review+of+Controlled-Trials+for+PTSD+in+Maltreated+Children+and+Adolescents.&amp;aulast=Bennett&amp;pid=%3Cauthor%3EBennett+RS%3C%2Fauthor%3E%3CAN%3E33016112%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/10.1177/1077559520961176
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1077559520961176
ER  -
TY  - JOUR
AB  - In the present meta-analysis, we examined the effect of cognitive training on the Executive Functions (EFs) of preschool children (age range: 3-6 years). We selected a final set of 32 studies from 27 papers with a total sample of 123 effect sizes. We found an overall effect of cognitive training for improving EF (g = 0.352; k = 123; p &lt; 0.001), without significant difference between near and far transfer effects on executive domains. No significant additional outcome effects were found for behavioral- and learning-related outcomes. Cognitive training programs for preschoolers are significantly more effective for developmentally at-risk children (ADHD or low socio-economic status) than for children with typical development and without risks. Other significant moderators were: computerized vs. non-computerized training, individual vs. group sessions, and length of training. The number of sessions was not a significant moderator. This is the first demonstration of cognitive training for transfer effects among different executive processes. We discuss this result in relationship to the lower level of modularization of EFs in younger children. Protocol Registration: PROSPERO (CRD42019124127). Available online at: https://www.crd.york.ac.uk/prospero/ display_record.php?ID=CRD42019124127..
AD  - [Scionti, Nicoletta; Cavallero, Marina; Zogmaister, Cristina; Marzocchi, Gian Marco] Univ Milano Bicocca, Dept Psychobgy, Milan, Italy.Marzocchi, GM (reprint author), Univ Milano Bicocca, Dept Psychobgy, Milan, Italy.gianmarco.marzocchi@unimib.it
AN  - WOS:000509268400001
AU  - Scionti,
AU  - N.
AU  - Cavallero,
AU  - M.
AU  - Zogmaister,
AU  - C.
AU  - Marzocchi,
AU  - G.
AU  - M.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3389/fpsyg.2019.02812
J2  - Front. Psychol.
KW  - executive functions
KW  - EF training
KW  - cognitive training
KW  - preschoolers
KW  - meta-analysis
KW  - working-memory
KW  - fluid intelligence
KW  - self-regulation
KW  - children
KW  - skills
KW  - disorder
KW  - program
KW  - interventions
KW  - efficiency
KW  - deficits
KW  - Psychology
L1  - internal-pdf://1987358283/Scionti-2020-Is Cognitive Training Effective f.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: KF5FTTimes Cited: 0Cited Reference Count: 89Scionti, Nicoletta Cavallero, Marina Zogmaister, Cristina Marzocchi, Gian Marco03Frontiers media saLausanne
PY  - 2020
SP  - 23
T2  - Frontiers in Psychology
TI  - Is Cognitive Training Effective for Improving Executive Functions in Preschoolers? A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000509268400001
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/482835/pubmed-zip/.versions/1/.package-entries/fpsyg-10-02812/fpsyg-10-02812.pdf?sv=2015-12-11&amp;sr=b&amp;sig=omy4IGf2EZWHpL%2Fd%2FuWExbhdf%2B1eJxkV9CYydmEiaN8%3D&amp;se=2020-03-20T06%3A25%3A20Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyg-10-02812.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **Background:** 
Self-harm is a clinically relevant and prevalent behaviour which peaks in adolescence. Given the high prevalence of self-harm, the high levels of psychiatric comorbidity, and its role as a risk factor for suicide, delivering evidence-based care is critical.

**Methods:** 
We conducted a systematic review and meta-analysis of the literature on treating self-harm in adolescents (12-19 years) published in the last 20 years, identifying 25 randomised controlled trials. We calculated the effect of treatment interventions relative to active control conditions in reducing self-harm, suicidal ideation and depressive symptoms.

**Results:** 
Overall, treatment interventions fared slightly better than active controls in decreasing self-harm (d = 0.13, 95% CI 0.04-0.22, p = .004), suicidal ideation (d = 0.31, 95% CI 0.12-0.50, p = .001) and depressive symptoms (d = 0.22, 95% CI 0.07-0.38, p = .006). Subgroup analysis of specific therapies revealed moderate effects of DBT-A in reducing self-harm (d = 0.51, 95% CI 0.18-0.85, p = .002) and suicidal ideation (d = 0.48, 95% CI 0.17-0.80, p = .003), as well as moderate effects of family-centred therapy in the treating suicidal ideation (d = 0.58, 95% CI 0.01-1.15, p = .049).

**Conclusions:** 
The findings of our meta-analysis indicate that, overall, currently available treatments are effective in treating self-harm, suicidal ideation, and depressive symptoms in adolescence. Although the treatment intervention conditions showed only small to moderate effects in comparison to active controls, these differences were statistically significant and are clinically important. Further research is needed to understand the reduction in self-harm within active controls, which may arise due to the natural course of self-harm, or the potential efficacy of treatment as usual and enhanced usual care. Given the significant reduction of self-harm in active control conditions, delivering effective care to a large number of adolescents with self-harm may require developing stepped-care models in clinical practice. Expensive and poorly available treatments should be targeted at young people who most need them.
AD  - Kothgassner, Oswald D. 1Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.Robinson, Kealagh. 2School of Psychology, Victoria University of Wellington, Wellington, New Zealand.Goreis, Andreas. 3Department of Clinical and Health Psychology, Faculty of Psychology, University of Vienna, Vienna, Austria.Goreis, Andreas. 4Outpatient Unit for Research, Teaching and Practice, Faculty of Psychology, University of Vienna, Vienna, Austria.Ougrin, Dennis. 5Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King&#039;s College London, London, UK.Plener, Paul L. 1Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.Plener, Paul L. 6Department of Child- and Adolescent Psychiatry and Psychotherapy, Medical University of Ulm, Ulm, Germany.
AN  - 32426138
AU  - Kothgassner,
AU  - O.
AU  - D.
AU  - Robinson,
AU  - K.
AU  - Goreis,
AU  - A.
AU  - Ougrin,
AU  - D.
AU  - Plener,
AU  - P.
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s40479-020-00123-9
DP  - Ovid Technologies
J2  - Borderline Personal Disord Emot Dysregul
L1  - internal-pdf://1140947557/Kothgassner-2020-Does treatment method matter_.pdf
LA  - English
M3  - Review
N1  - Kothgassner, Oswald DRobinson, KealaghGoreis, AndreasOugrin, DennisPlener, Paul L
PY  - 2020
SP  - 16
T2  - Borderline Personality Disorder and Emotion Dysregulation
TI  - Does treatment method matter? A meta-analysis of the past 20 years of research on therapeutic interventions for self-harm and suicidal ideation in adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32426138
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216729/pdf/40479_2020_Article_123.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Early intensive applied behaviour analysis-based interventions are intensive interventions for autistic children that are often delivered on a one-to-one basis for 20-50 hours per week.

OBJECTIVES: 
To evaluate the clinical effectiveness and cost-effectiveness of early intensive applied behaviour analysis-based interventions for autistic children, based on current evidence.

METHODS: 
A systematic review and individual participant data meta-analysis were conducted to evaluate the clinical effectiveness of an early intensive applied behaviour analysis-based intervention for autistic children. An economic analysis included a review of existing analyses and the development of a new model.

RESULTS: 
Twenty studies were included in the clinical review. Individual participant data were retrieved from 15 of these studies. Results favoured the interventions when assessing adaptive behaviour after 2 years compared with treatment as usual/eclectic interventions (mean difference 7.00, 95% confidence interval 1.95 to 12.06). In analyses of cognitive ability (intelligence quotient), results favoured the interventions by approximately 10 points after 1 year (mean difference 9.16, 95% confidence interval 4.38 to 13.93) and 2 years (mean difference 14.13, 95% confidence interval 9.16 to 19.10). Evidence for other outcomes was limited and meta-analyses were generally inconclusive. There was no evidence that the effect of the interventions varied with characteristics of the children, but data were limited. Adopting a 30,000 per quality-adjusted life-year threshold, the results of the cost-effectiveness analysis indicate that early intensive applied behaviour analysis-based interventions would need to generate larger benefits or cost savings to be cost-effective. Adopting a public sector perspective and making pessimistic assumptions about long-term effects, the incremental cost-effectiveness ratio for early intensive applied behaviour analysis-based therapy compared with treatment as usual is 189,122 per quality-adjusted life-year. When optimistic assumptions are made, the incremental cost-effectiveness ratio is 46,768 per quality-adjusted life-year. Scenario analyses indicated that these interventions can potentially be cost-effective if long-term improvements persist into adulthood, or if they have significant impact on educational placement. Care should be taken when interpreting these scenarios owing to the limited data.

LIMITATIONS: 
All included studies were at risk of bias, there was substantial heterogeneity and effects varied considerably across studies. The effect of intervention on autism symptom severity, language development and school placement remains uncertain because of the limited data. The long-term effects are unclear owing to a lack of follow-up data.

CONCLUSIONS: 
This review found limited evidence that early intensive applied behaviour analysis-based interventions may improve cognitive ability and adaptive behaviour, but the long-term impact of the interventions remains unknown. The economic analysis is constrained by the limited effectiveness evidence, but suggests that these interventions are unlikely to be cost-effective unless clear long-term benefits, or a substantial change in which schools children attend, can be identified.

FUTURE WORK: 
Further studies into the effectiveness of early intensive applied behaviour analysis-based interventions may be warranted if they include well-defined, alternative interventions as comparators and collect relevant outcomes. Consideration should be given to future studies that not only address whether or not early intensive applied behaviour analysis-based interventions are clinically effective, but also aim to identify which components of early intensive applied behaviour analysis-based interventions might drive effectiveness.

STUDY REGISTRATION: This study is registered as PROSPERO CRD42017068303.

FUNDING: 
This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 24, No. 35. See the NIHR Journals Library website for further project information.
AD  - Rodgers, Mark. Centre for Reviews and Dissemination, University of York, York, UK.Marshall, David. Centre for Reviews and Dissemination, University of York, York, UK.Simmonds, Mark. Centre for Reviews and Dissemination, University of York, York, UK.Le Couteur, Ann. Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK.Biswas, Mousumi. Centre for Reviews and Dissemination, University of York, York, UK.Wright, Kath. Centre for Reviews and Dissemination, University of York, York, UK.Rai, Dheeraj. Bristol Medical School, University of Bristol, Bristol, UK.Palmer, Stephen. Centre for Health Economics, University of York, York, UK.Stewart, Lesley. Centre for Reviews and Dissemination, University of York, York, UK.Hodgson, Robert. Centre for Reviews and Dissemination, University of York, York, UK.
AN  - 32686642
AU  - Rodgers,
AU  - M.
AU  - Marshall,
AU  - D.
AU  - Simmonds,
AU  - M.
AU  - Le
AU  - Couteur,
AU  - A.
AU  - Biswas,
AU  - M.
AU  - Wright,
AU  - K.
AU  - Rai,
AU  - D.
AU  - Palmer,
AU  - S.
AU  - Stewart,
AU  - L.
AU  - Hodgson,
AU  - R.
DA  - Jul
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3310/hta24350
DP  - Ovid Technologies
J2  - Health Technol Assess
L1  - internal-pdf://1867154395/Rodgers-2020.pdf
LA  - English
M3  - Systematic Review
N1  - Rodgers, MarkMarshall, DavidSimmonds, MarkLe Couteur, AnnBiswas, MousumiWright, KathRai, DheerajPalmer, StephenStewart, LesleyHodgson, Robert
PY  - 2020
SP  - 1-306
T2  - Health Technology Assessment (Winchester, England)
TI  - Interventions based on early intensive applied behaviour analysis for autistic children: a systematic review and cost-effectiveness analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32686642
VL  - 24
ER  -
TY  - JOUR
AB  - Active supervision is a proactive, low-intensity strategy to minimize challenging behaviors and increase desired behaviors. To examine the evidence base of this strategy, we applied the Council for Exceptional Children&#039;s (CEC) Standards for Evidence-Based Practices in Special Education to the body of research exploring the impact of active supervision with Pre-K-12 students in traditional school settings. In this systematic literature review, we identified seven peer-reviewed, single-case design, treatment-outcome studies meeting inclusion criteria. All studies met a &gt;= 80% weighted criterion of CEC&#039;s quality indicators. These seven studies included 15 cases aggregated at the school, classroom, or grade level, collectively involving 1,686 participants. Three studies included three or more cases and demonstrated positive effects across primary dependent variables (with one study showing neutral effects on a secondary dependent variable). Based on available evidence and using CEC criteria, we determined active supervision to be a potentially evidence-based practice. We discuss implications, limitations, and future directions. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2020-26597-003
AU  - Allen,
AU  - G.
AU  - E.
AU  - Common,
AU  - E.
AU  - A.
AU  - Germer,
AU  - K.
AU  - A.
AU  - Lane,
AU  - K.
AU  - L.
AU  - Buckman,
AU  - M.
AU  - M.
AU  - Oakes,
AU  - W.
AU  - P.
AU  - Menzies,
AU  - H.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/0198742919837646
L1  - internal-pdf://0399525729/Allen-2020-A systematic review of the evidence.pdf
PY  - 2020
SP  - 167-182
T2  - Behavioral Disorders
TI  - A systematic review of the evidence base for active supervision in Pre-K-12 settings
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-26597-003
UR  - https://journals.sagepub.com/doi/10.1177/0198742919837646
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0198742919837646
VL  - 45
ER  -
TY  - JOUR
AB  - Promoting self-determination is critical to enabling young people to achieve education-related goals and positive postschool employment, community participation, and quality of life outcomes. By developing skills associated with self-determination such as choice-making, decision-making, problem solving, goal setting and attainment, planning, self-management, self-advocacy, self-awareness, and self-knowledge, students with disabilities are better prepared to make purposeful decisions and choices. 

We conducted a meta-analysis of the literature on interventions to promote self-determination and associated skills with students with disabilities in the school context. We analyzed the types of interventions, populations of students with whom they were implemented, outcomes, and rigor of research. 

**Results** demonstrated that interventions to promote self-determination can be effective for students across grade levels, disability labels, and settings. There remains a need for increased focus on promoting self-determination within inclusive, general education settings with students with and without disabilities and of diverse backgrounds. Future researchers should also focus on the rigor of methodological design and associated reporting when conducting school-based research. Additional implications for research and practice are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Raley, Sheida K.: raley@ku.eduRaley, Sheida K.: Department of Special Education, University of Kansas, Joseph R. Pearson Hall, Room 517, 1122 West Campus Road, Lawrence, KS, US, 66045, raley@ku.eduBurke, Kathryn M.: University of Kansas, Lawrence, KS, USRaley, Sheida K.: University of Kansas, Lawrence, KS, USShogren, Karrie A.: University of Kansas, Lawrence, KS, USHagiwara, Mayumi: University of Kansas, Lawrence, KS, USMumbardo-Adam, Cristina: Universitat Ramon Llull, Barcelona, SpainUyanik, Hatice: University of Kansas, Lawrence, KS, USBehrens, Sarah: University of Kansas Edwards Campus, Overland Park, KS, US
AN  - 2020-33186-005
AU  - Burke,
AU  - K.
AU  - M.
AU  - Raley,
AU  - S.
AU  - K.
AU  - Shogren,
AU  - K.
AU  - A.
AU  - Hagiwara,
AU  - M.
AU  - Mumbardo-Adam,
AU  - C.
AU  - Uyanik,
AU  - H.
AU  - Behrens,
AU  - S.
DA  - Jun
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/0741932518802274
DP  - Ovid Technologies
KW  - self-determination, disabilities, intervention, meta-analysis
KW  - *Decision Making
KW  - *Disabilities
KW  - *Self-Determination
KW  - *Special Education Students
KW  - Goal Setting
KW  - Quality of Life
KW  - Self-Management
KW  - Special &amp; Remedial Education [3570]
KW  - Human
L1  - internal-pdf://0571103579/Burke-2020.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2020
SP  - 176-188
T2  - Remedial and Special Education
TI  - A meta-analysis of interventions to promote self-determination for students with disabilities
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-33186-005
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F0741932518802274&amp;issn=0741-9325&amp;isbn=&amp;volume=41&amp;issue=3&amp;spage=176&amp;pages=176-188&amp;date=2020&amp;title=Remedial+and+Special+Education&amp;atitle=A+meta-analysis+of+interventions+to+promote+self-determination+for+students+with+disabilities.&amp;aulast=Burke&amp;pid=%3Cauthor%3EBurke%2C+Kathryn+M%3C%2Fauthor%3E%3CAN%3E2020-33186-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/10.1177/0741932518802274
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0741932518802274
VL  - 41
ER  -
TY  - JOUR
AB  - **Background**
Migrants who have been forced to leave their home, such as refugees, asylum seekers, and internally displaced persons (IDP), are likely to experience stressors which may lead to mental health problems. The efficacy of interventions for mental health promotion, prevention, and treatment may differ in this population.

**Objectives**
With this overview of systematic reviews, we will map the characteristics and methodological quality of existing systematic reviews and registered systematic review protocols on the promotion of mental health and prevention and treatment of common mental disorders among refugees, asylum seekers, and IDPs. The findings from this overview will be used to prioritise and inform future Cochrane reviews on the mental health of involuntary migrants.

**Methods**
We searched Ovid MEDLINE (1945 onwards), Ovid Embase (1974 onwards), Ovid PsycINFO, ProQuest PTSDpubs, Web of Science Core Collection, Cochrane Database of Systematic Reviews, NIHR Journals Library, CRD databases (archived), DoPHER, Epistemonikos, Health Evidence, 3ie International Initiative for Impact Evaluation, and PROSPERO, to identify systematic reviews of mental health interventions for involuntary migrants. We did not apply any restrictions on date, language, or publication status to the searches. We included systematic reviews or protocols for systematic reviews of interventions aimed at refugees, asylum seekers, and internally displaced persons. Interventions must have been aimed at mental health promotion (for example, classroom‐based well‐being interventions for children), prevention of mental health problems (for example, trauma‐focussed Cognitive Behavioural Therapy to prevent post‐traumatic stress disorder), or treatment of common mental disorders and symptoms (for example, narrative exposure therapy to treat symptoms of trauma). After screening abstracts and full‐text manuscripts in duplicate, we extracted data on the characteristics of the reviews, the interventions examined in reviews, and the number of primary studies included in each review. Methodological quality of the included systematic reviews was assessed using AMSTAR 2.

**Main results**
The overview includes 23 systematic reviews and 15 registered systematic review protocols.Of the 23 published systematic reviews, meta‐analyses were conducted in eight reviews. It was more common for the search strategy or inclusion criteria of the reviews to state that studies involving refugees were eligible for inclusion (23/23), than for asylum seekers (14/23) or IDPs (7/23) to be explicitly mentioned. In most reviews, study eligiblity was either not restricted by participant age (9/23), or restricted to adults (10/23). Reviews commonly reported on studies of diagnosis or symptoms of post‐traumatic stress disorder or trauma (11/23) and were less likely to report on depression or anxiety (6/23). In 15 reviews the intervention of interest was focused on/ specific to psychological therapy. Across all 23 reviews, the interventions most commonly identified from primary studies were general Cognitive Behavioural Therapy, Narrative Exposure Therapy, and a range of different integrative and interpersonal therapies. Even though many reviews included studies of participants without a diagnosis of a mental health problem, they often assessed mental health treatments and did not usually distinguish between promotion, prevention, and treatment in the review aims.Together the 23 systematic reviews included 336 references, of which 175 were unique primary studies. Limitations to the methodological quality of reviews most commonly related to reporting of selection criteria (21/23), absence of a protocol (19/23), reporting of study design (20/23), search strategy (22/23), and funding sources of primary studies (19/23).

**Authors&#039; conclusions**
Gaps exist in the evidence on mental health interventions for refugees, asylum seekers, and internally displaced persons. Most reviews do not specify that internally displaced persons are included in the selection criteria, even though they make up the majority of involuntary migrants worldwide. Reviews specific to mental health promotion and prevention of common mental disorders are missing, and there is more evidence available for adults or mixed populations than for children. The literature is focused on post‐traumatic stress disorder and trauma‐related symptoms, with less attention for depression and anxiety disorders. Better quality systematic reviews and better report of review design and methods would help those who may use these reviews to inform implementation of mental health interventions.
AU  - Uphoff,
AU  - E.
AU  - Robertson,
AU  - L.
AU  - Cabieses,
AU  - B.
AU  - Villal&oacute;n,
AU  - F.
AU  - J.
AU  - Purgato,
AU  - M.
AU  - Churchill,
AU  - R.
AU  - Barbui,
AU  - C.
DA  - September
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013458.pub2
L1  - internal-pdf://2405570299/Uphoff_et_al-2020-Cochrane_Database_of_Systema.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - An overview of systematic reviews on mental health promotion, prevention, and treatment of common mental disorders for refugees, asylum seekers, and internally displaced persons
ER  -
TY  - JOUR
AB  - Social skills training (SST) for autism spectrum disorder (ASD) has traditionally focused on face-to-face (F2F-SST) interventions. Recently, Behavioral Intervention Technologies (BITs-SST) have been utilized to target social skills deficits using computer-based programs, avatars, and therapeutic robots. The present meta-analysis reviews recent evidence and compares the efficacy of 14 F2F-SST and four identified BITs-SST intervention trials for youth with ASD. These preliminary analyses did not indicate significant differences between F2F-SST and BITs-SST, with effect sizes consistently in the medium to high range (g = 0.81 and g = 0.93, respectively). These findings provide initial support for the continued investigation of BITs for providing SST to youth with ASD.
AD  - Soares, Erin E. Department of Clinical Psychology at the Pacific Graduate School of Psychology, Palo Alto University, Palo Alto, USA.Soares, Erin E. Children and Adolescents Psychotherapy and Technology (CAPT), Palo Alto University, Palo Alto, USA.Bausback, Kimberly. Department of Clinical Psychology at the Pacific Graduate School of Psychology, Palo Alto University, Palo Alto, USA.Bausback, Kimberly. Children and Adolescents Psychotherapy and Technology (CAPT), Palo Alto University, Palo Alto, USA.Beard, Charlotte L. Department of Clinical Psychology at the Pacific Graduate School of Psychology, Palo Alto University, Palo Alto, USA.Beard, Charlotte L. Children and Adolescents Psychotherapy and Technology (CAPT), Palo Alto University, Palo Alto, USA.Higinbotham, Megan. Department of Clinical Psychology at the Pacific Graduate School of Psychology, Palo Alto University, Palo Alto, USA.Higinbotham, Megan. Children and Adolescents Psychotherapy and Technology (CAPT), Palo Alto University, Palo Alto, USA.Bunge, Eduard L. Department of Clinical Psychology at the Pacific Graduate School of Psychology, Palo Alto University, Palo Alto, USA.Bunge, Eduard L. Children and Adolescents Psychotherapy and Technology (CAPT), Palo Alto University, Palo Alto, USA.Gengoux, Grace W. Department of Psychiatry &amp; Behavioral Sciences, Stanford University School of Medicine, Stanford, CA USA.
AN  - 33225056
AU  - Soares,
AU  - E.
AU  - E.
AU  - Bausback,
AU  - K.
AU  - Beard,
AU  - C.
AU  - L.
AU  - Higinbotham,
AU  - M.
AU  - Bunge,
AU  - E.
AU  - L.
AU  - Gengoux,
AU  - G.
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s41347-020-00177-0
DP  - Ovid Technologies
J2  - J
L1  - internal-pdf://4059663567/Soares-2020-Social Skills Training for Autism.pdf
LA  - English
N1  - Soares, Erin EBausback, KimberlyBeard, Charlotte LHiginbotham, MeganBunge, Eduard LGengoux, Grace W
PY  - 2020
SP  - 1-15
T2  - Journal of Technology in Behavioral Science
TI  - Social Skills Training for Autism Spectrum Disorder: a Meta-analysis of In-person and Technological Interventions
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33225056
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33225056&amp;id=doi:10.1007%2Fs41347-020-00177-0&amp;issn=2366-5963&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-15&amp;date=2020&amp;title=Journal+of+Technology+in+Behavioral+Science&amp;atitle=Social+Skills+Training+for+Autism+Spectrum+Disorder%3A+a+Meta-analysis+of+In-person+and+Technological+Interventions.&amp;aulast=Soares&amp;pid=%3Cauthor%3ESoares+EE%3C%2Fauthor%3E%3CAN%3E33225056%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s41347-020-00177-0.pdf
ER  -
TY  - JOUR
AB  - Parent-mediated interventions (PMIs) are commonly used with children with autism spectrum disorder (ASD), and their effectiveness for young children has been documented. However, no reviews have examined the use of PMIs with older children with ASD. Therefore, the purpose of this review is to investigate the state of the literature regarding PMIs for school-age children with ASD and to evaluate their effectiveness across domains. Eighteen studies of PMIs examining 170 child participants with ASD were included. Participants, interventions, and the effects of the interventions are described. Overall, studies demonstrated moderately positive effects for PMIs for school-age children with ASD. Group design studies demonstrated an overall effect size (ES) of 0.79, 95% confidence interval (CI) = [0.50, 1.09], while single-case design (SCD) studies yielded an overall ES of 1.84, 95% CI = [1.08, 2.60]. More research is needed to understand the differential effectiveness of parent training components, and future research should focus on including measures of parent treatment integrity, to aid in the understanding of program efficacy. Copyright &copy; Hammill Institute on Disabilities 2020.
AD  - (Ratliff-Black, Therrien) University of Virginia, Charlottesville, United StatesM. Ratliff-Black, University of Virginia, Charlottesville, United States. E-mail: meb2kn@virginia.edu
AN  - 2006735654
AU  - Ratliff-Black,
AU  - M.
AU  - Therrien,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1088357620956904
DP  - Ovid Technologies
KW  - autism spectrum disorders
KW  - evidence-based practices
KW  - parent
KW  - training
KW  - article
KW  - autism
KW  - child
KW  - comparative effectiveness
KW  - effect size
KW  - female
KW  - human
KW  - male
KW  - meta analysis
KW  - program efficacy
L1  - internal-pdf://1025791594/Ratliff-Black-2020-Parent-Mediated Interventio.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - Focus on Autism and Other Developmental Disabilities.
TI  - Parent-Mediated Interventions for School-Age Children With ASD: A Meta-Analysis
UR  - http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201875
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2006735654
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1177%2F1088357620956904&amp;issn=1088-3576&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1088357620&amp;pages=&amp;date=2020&amp;title=Focus+on+Autism+and+Other+Developmental+Disabilities&amp;atitle=Parent-Mediated+Interventions+for+School-Age+Children+With+ASD%3A+A+Meta-Analysis&amp;aulast=Ratliff-Black&amp;pid=%3Cauthor%3ERatliff-Black+M.%3C%2Fauthor%3E%3CAN%3E2006735654%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1088357620956904
ER  -
TY  - JOUR
AB  - BACKGROUND: Pediatric tuina is used to prevent and treat disease by employing various manipulative techniques on specific parts of the body, appropriate to the child&#039;s specific physiological and pathological characteristics.

OBJECTIVE: To evaluate the effects and safety of pediatric tuina as a non-pharmaceutical therapy for anorexia in children under 14 years.

METHODS: Randomized controlled trials (RCTs) comparing pediatric tuina with medicine for anorexia were included in this review. Six electronic databases were searched from inception to June 2019. Two authors independently extracted data and assessed the risk of bias. Significant effective rate (defined as appetite improved and food intake returning to 3/4 or more of normal intake) was used as primary outcome. Secondary outcomes included food intake, compliance and adverse events. Trial sequential analysis (TSA) was used to calculate the required information size in a meta-analysis and to detect the robustness of the results. Certainty of the evidence was assessed using the online GRADEpro tool.

RESULTS: Of the included 28 RCTs involving 2650 children, the majority had a high or unclear risk of bias in terms of allocation concealment, blinding, and selective reporting. All trials compared tuina with western medicine or Chinese herbs. For significant effective rate, meta-analysis showed that tuina was superior to western medicine (risk ratio (RR) 1.68, 95 % confidence interval (CI) [1.35, 2.08]) and Chinese herbs (RR 1.36, 95 % CI [1.19, 1.55]). For food intake, 9 trials evaluated it in the form of score (1 points, 2 points, 4 points and 6 points) calculated according to the reduction degree of food intake. Six points represented the most serious. Meta-analysis showed tuina was superior to western medicine (mean difference (MD) -0.88, 95 % CI [-1.27, -0.50]) and Chinese herbs (MD -0.69, 95 % CI [-1.00, -0.38]) on lightening the reduction degree of food intake. Two trials reported compliance and six trials reported no adverse events occurred in pediatric tuina group. TSA for significant effective rate demonstrated that the pooled data had insufficient power regarding both numbers of trials and participants.

CONCLUSIONS: Low certainty of evidence suggested pediatric tuina was beneficial and safe for the treatment of anorexia in children under 14 years. Furthermore well-designed RCTs with adequate sample sizes are needed.
AD  - Liang, Shi-Bing. Centre for Evidence-Based Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China; School of Basic Medicine, Shanxi University of Chinese Medicine, Taiyuan, 030000, China. Electronic address: zyi20126185@163.com.Lai, Bao-Yong. The Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address: baoyonglai@bucm.edu.cn.Cao, Hui-Juan. Centre for Evidence-Based Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address: huijuancao327@hotmail.com.Cai, Qiu-Han. Clinical Trial Center, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China. Electronic address: happyqiuhan@126.com.Bai, Xue. Centre for Evidence-Based Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address: 20170931127@bucm.edu.cn.Li, Jing. Centre for Evidence-Based Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address: lj@bucm.edu.cn.Zhang, Ya-Peng. Centre for Evidence-Based Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address: zhangyapeng@bucm.edu.cn.Chi, Yuan. Centre for Evidence-Based Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address: chiyuan0717@163.com.Robinson, Nicola. School of Health and Social Care, London South Bank University, London, SE1 0AA, UK; Centre for Evidence-Based Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address: nicky.robinson@lsbu.ac.uk.Liu, Jian-Ping. Centre for Evidence-Based Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China; Institute of Integrated Traditional Chinese Medicine and Western Medicine, Guangzhou Medical University, Guangzhou, China; National Research Center in Complementary and Alternative Medicine (NAFKAM), Department of Community Medicine, Faculty of Health Science, UiT, The Arctic University of Norway, 9037 Tromso, Norway. Electronic address: Liujp@bucm.edu.cn.
AN  - 32507428
AU  - Liang,
AU  - S.
AU  - B.
AU  - Lai,
AU  - B.
AU  - Y.
AU  - Cao,
AU  - H.
AU  - J.
AU  - Cai,
AU  - Q.
AU  - H.
AU  - Bai,
AU  - X.
AU  - Li,
AU  - J.
AU  - Zhang,
AU  - Y.
AU  - P.
AU  - Chi,
AU  - Y.
AU  - Robinson,
AU  - N.
AU  - Liu,
AU  - J.
AU  - P.
DA  - Jun
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ctim.2020.102411
DP  - Ovid Technologies
J2  - Complement Ther Med
L1  - internal-pdf://3180047639/Liang-2020-Pediatric tuina for the treatment o.pdf
LA  - English
M3  - Review
N1  - Liang, Shi-BingLai, Bao-YongCao, Hui-JuanCai, Qiu-HanBai, XueLi, JingZhang, Ya-PengChi, YuanRobinson, NicolaLiu, Jian-PingS0965-2299(19)31780-7
PY  - 2020
SP  - 102411
T2  - Complementary Therapies in Medicine
TI  - Pediatric tuina for the treatment of anorexia in children under 14 years: a systematic review and meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32507428
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32507428&amp;id=doi:10.1016%2Fj.ctim.2020.102411&amp;issn=0965-2299&amp;isbn=&amp;volume=51&amp;issue=&amp;spage=102411&amp;pages=102411&amp;date=2020&amp;title=Complementary+Therapies+in+Medicine&amp;atitle=Pediatric+tuina+for+the+treatment+of+anorexia+in+children+under+14+years%3A+a+systematic+review+and+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Liang&amp;pid=%3Cauthor%3ELiang+SB%3C%2Fauthor%3E%3CAN%3E32507428%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/272589/1-s2.0-S0965229920X00033/1-s2.0-S0965229919317807/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEIT%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJHMEUCIEQXRJM1i7a9BX0fAcOkueenMAPBeJ8hcp8RUWxY8hK%2BAiEAzFCHpyvyjeGOLUT%2FCw0A94YRtXjoANdw3fuqjBBoJi4qtAMILRADGgwwNTkwMDM1NDY4NjUiDAThwCD9Qk0a8H7GNyqRA4J0h%2Bw0n7jPiFXZvC1POMKMUWxsyzmWtuMnRlCqpmJjAJ1DnGzPY%2B0ITklTvy9Z3gfVBsQ1%2BZJFMiZB4ED2NlqwayXlYFVdkhYxCXrSljZoSchpRkNg0a1uXQEYFhWHzik5fl3hHgF8%2FhaV0mpl65jzHVSgP1C%2F7a%2BBAoYaJXlqN6FWlmieUYg%2B78dnO7u58B5g6nVI52u%2BnOjBGAzv2k6yQ0p1o7qSSCSJN0f9TX2RsFp6vBZJhYcpx1J0bdLIcY5C6MSlvRpRgewopU%2Br5nRODurhvhTNxmdU08zNi2VvfmARbIiuM1JH4CDqzvRdeOnAQS%2FFbsjJHN12kpoaqHQ%2Bu8C1QKdHNKy0731f8RGSkIu6eumNor3miGbTAAkX9f27Rm82QmRFZSLdoimy1u4%2FLWNr%2BUP1ZSR7cv6NzP91%2BLkPJ8pcLdKxEMZNTR5eJrSZSaaJT3g7sc4VKtKls%2FVHsbiempR%2FHBZBoIXYgLGYqew4weElAWZkV31pT9jau66vYJsvGulEBIFNO2sFfGAqMOSfofgFOusBDAIuzaiDXiA0K5Ewzwfe4dtWHqJdig4epmpYs%2B7BQAyKAnLwiCgTdnQawZMTntYT575uB5uM8KRexfQ3ixL9tHPy%2FqnBMWbMQfj9nK2Sld4wYeRfqI6aQCZdvpCGURqOJrruCrpK5vDXTybQhH%2B%2BQgTk1gKLWbdP9qAuHVSao%2Fu78szaWLfy1L7dnF7QqV8lSgHShkhbqIDaVK4DFKKKXg8YGumPxlvfp6bGonIKGhMS0rzNAsDLe%2BLDgGrFXoKS0KJhzR5bhQnkc1DnsAo%2BQtyyoCRbNY7hmKQsoO8CaCXvco8IRzplLpZXRA%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200710T122210Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYXOUESSE6%2F20200710%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=90e6c2aaaa621231469b2f01f9f9eaeb3a563d3a83090c5d40a152f19413187f&amp;hash=2887c01a036bef8827e7656521107c306b414faec3677654165c856fab31e131&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0965229919317807&amp;tid=spdf-8784f36d-e60c-40f0-9e77-3c9808c57f53&amp;sid=7db55e4a1e53c345f64a15b643c885f9597cgxrqb&amp;type=client
VL  - 51
ER  -
TY  - JOUR
AB  - Bullying is a serious public health concern across the globe. While there are a number of bullying interventions with parental components, limited efforts have been made to synthesize the impacts of parenting programs on bullying prevention. This meta-analysis aimed to review and examine parenting programs on bullying reduction that involving both school-based and home visiting anti-bullying programs. The overall effect size supported a significant outcome on bullying reduction (d = .640, 95% confidence interval [CI] [0.239, 1.041]). Results of this meta-analysis reported that participants in the parenting programs scored significantly lower on both bullying and victimization. Data from the randomized controlled trials and the pre- and posttest design studies showed evidence of highly significant effects of parenting interventions on bullying reduction. Child- and parent-related factors including parenting style, children&#039;s empathy, and parent-child interaction about bullying were found to be significantly related to the effectiveness of intervention programs. This study provides evidence to enhance policy and practice for effectively enabling parent involvement in bullying behavior reduction and to increase parent-children communication about bullying as well as parenting skills. Future researchers and practitioners may explore more about the impact of school-family partnerships and their reliance on each other to help reduce bullying.
AD  - Chen, Qiqi. Department of Applied Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong.Zhu, Yuhong. Department of Social Work and Social Policy, School of Sociology &amp; Population Studies, Renmin University of China, Beijing, China.Chui, Wing Hong. Department of Social and Behavioral Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong.
AN  - 32242506
AU  - Chen,
AU  - Q.
AU  - Zhu,
AU  - Y.
AU  - Chui,
AU  - W.
AU  - H.
DA  - Apr 03
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1524838020915619
DP  - Ovid Technologies
J2  - Trauma Violence Abuse Rev J
L1  - internal-pdf://0050837747/Chen-2020-A Meta-Analysis on Effects of Parent.pdf
LA  - English
N1  - Chen, QiqiZhu, YuhongChui, Wing Hong
PY  - 2020
T2  - Trauma Violence &amp; Abuse
TI  - A Meta-Analysis on Effects of Parenting Programs on Bullying Prevention
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32242506
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32242506&amp;id=doi:10.1177%2F1524838020915619&amp;issn=1524-8380&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1524838020915619&amp;pages=1524838020915619&amp;date=2020&amp;title=Trauma+Violence+%26+Abuse&amp;atitle=A+Meta-Analysis+on+Effects+of+Parenting+Programs+on+Bullying+Prevention.&amp;aulast=Chen&amp;pid=%3Cauthor%3EChen+Q%3C%2Fauthor%3E%3CAN%3E32242506%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/10.1177/1524838020915619
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1524838020915619
ER  -
TY  - JOUR
AB  - Compared to the use of Acceptance and Commitment Therapy (ACT) in the treatment of adult psychopathology, there are fewer empirical studies on children, which makes it difficult to summarize the use of ACT in children. The current study presented the results of a meta-analysis of 14 randomized controlled trials (RCTs) on the efficacy of ACT for 1189 children. Compared with treatment as usual (TAU) and waitlist, ACT significantly improved the symptoms of primary outcome measures such as anxiety and depression [SMD = -0.59, CI(-0.87, -0.31), p &lt; 0.001; SMD = -0.86, CI(-1.13, -0.59), p &lt; 0.001]. However, there was no significant difference between ACT and traditional cognitive behavioral therapy (CBT). On secondary outcomes such as quality of life and well-being, ACT performed similarly to traditional CBT and TAU, but outperformed the untreated control group [SMD = 1.74, CI (0.78, 2.69), p &lt; 0.001; I2 = 82.8%]. Our findings indicate that ACT is more effective than TAU and untreated groups in treating anxiety, depression and other mental and behavioral disorders, while not superior to traditional CBT. We also found that there was no significant difference in effects on improving the positive mental factors and behaviors for children compared to existing and usual treatments, but ACT did outperform the untreated group. More high-quality research with an improved design that focuses on these positive mental factors and behaviors of children are needed to understand the efficacy of ACT for children. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - Ding, Dongyan: ddy0558@126.comDing, Dongyan, ddy0558@126.comFang, Shuanghu: Department of Psychology, Anhui Normal University, Wuhu, ChinaDing, Dongyan: Department of Psychology, Anhui Normal University, Wuhu, China
AN  - 2020-28725-027
AU  - Fang,
AU  - Shuanghu
AU  - Ding,
AU  - Dongyan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jcbs.2020.01.007
DP  - Ovid Technologies
KW  - Acceptance and Commitment Therapy, Children, efficacy
KW  - *Pediatrics
KW  - *Treatment Effectiveness Evaluation
KW  - *Treatment Outcomes
KW  - *Acceptance and Commitment Therapy
KW  - Cognitive Therapy [3311]
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://3856496706/Fang-2020-A meta-analysis of the efficacy of a.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
SP  - 225-234
T2  - Journal of Contextual Behavioral Science
TI  - A meta-analysis of the efficacy of acceptance and commitment therapy for children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2020-28725-027
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jcbs.2020.01.007&amp;issn=2212-1447&amp;isbn=&amp;volume=15&amp;issue=&amp;spage=225&amp;pages=225-234&amp;date=2020&amp;title=Journal+of+Contextual+Behavioral+Science&amp;atitle=A+meta-analysis+of+the+efficacy+of+acceptance+and+commitment+therapy+for+children.&amp;aulast=Fang&amp;pid=%3Cauthor%3EFang%2C+Shuanghu%3C%2Fauthor%3E%3CAN%3E2020-28725-027%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/282078/1-s2.0-S2212144719X00058/1-s2.0-S2212144719301954/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEK%2F%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQCYoch3fid2vjt1VYQPaP6elzGCPiGV78zYUWYXgV%2BXAQIhANWgO4W5eJfjDGYhN0%2FeHbyZX6LvQladuEm6SjYwpQ%2B0KrQDCCcQAxoMMDU5MDAzNTQ2ODY1IgydQRk7X7x0VmoMHZ4qkQMU62TSERz3puAvjg0HzBQ9f3fY5rgIpUDGanvdTI%2FZy%2BhCKku9LlHGYokyyM517hnNhRpsFvKLhk4Hb659sB5aUyorqNlJZnTQtIbhTTuJ7DbTTM2P8yqXSidy3miulgFAB4xqb5XowHbW24GArycot%2BADcuWD1ApkrJqj1QRYnWnVAWTWR3r88BpdMY45PxXjj3JwkNLilzXePc4n4sebzcJuHMLrg8nfUk53qgLfWF3QvVGTLJXYEVYb8hUs%2F0vUjGyp7csYSyCwm4H7YJmpH7V5y56ndFSvHA8Gmt62SyK%2B13%2Bn5XdCf6AMwFeKfwWXreVycvl%2BLFq51QIhE7eOfZhQbskUA4lTntvW%2FieSInmJlToU4s6%2F5REol3gvJAYvYopF8pnmapmlzjt2bdoHmyxWL2HVPA2Z3yN3YXk4Jv%2FZ5Y8OaaT%2FGNriuy8MsfH17lW17J5QCfDotnA%2FMCZy9Dp90pHhWXObx1WNZ%2F4NIESDW1QlJsxRWRFkTQAoGyTPcVBzsN2TEjVKhdigRMJFYjDz8IH3BTrqAQhgypEe6AC%2BYG16tBTY3uAeKMY4hnzxJPAFiJho6KNU5r1te44Wdhwd5QrAZPKLasdG%2FTm7gwv%2BeFmXsQVIyuPVJJhCnxjrSoSF%2FYF4lUo%2FOOpJtg0vZVfd6%2B7WH0EFIqh95L49DUA4A6SgrJvELadvlAywAq0DujY%2FDglzfxhb2UqvEL%2FGgGMqPfAuZRTvHD7DGiq3vfmPNZT4CapZCm5HaQmmAo%2ByiO6a7TjxTDIkWW5eY810eUa4%2BefZQMJBBk7fKc5fbvYXTSoUM24LmqMv%2BtrOkb4kTAA216yDSIQfAUwX%2F3iEymfc5A%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200610T065417Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY5EMXBNDQ%2F20200610%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=114c869bf4968a36b9b1f55a2baa25b0b4dc87c625873125e76ffbf158cdb156&amp;hash=eb7c748538d6001dcfb8fdedc1b8d6561cddf8b58a0dc6ef41571e593672fb1f&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S2212144719301954&amp;tid=spdf-d9f86e74-2802-4b13-98e6-6ef432a2582d&amp;sid=b6715d5b8d7fc143477ae8442de16298848bgxrqb&amp;type=client
VL  - 15
ER  -
TY  - JOUR
AB  - Computerized cognitive training programs (CCTP) are based on the assumption that cognitive abilities may be boosted by repetitively performing challenging tasks. The integration of game-like features in these programs, associated with the goal of amusing or rewarding participants, may contribute to generate cognitive benefits. Indeed, reinforcement contingencies have been reported to produce positive effects on performance and motivation, especially in children. This meta-analysis was aimed at providing a quantitative summary of the effectiveness of CCTP with game-like features in school-aged children with typical and atypical development. A total of 24 studies, with the cognitive and behavioral outcome data of 1547 participants, were selected for inclusion in the meta-analysis. Subgroup analyses were performed to identify the sources of the observed methodological heterogeneity. A robust variance estimation model, after removal of study outliers, yielded a small-to-moderate significant effect size. Final results pointed out smaller but more precise estimate effect sizes according to methodological aspects related to cognitive domain of outcomes, standardization of measures and type of control applied. Alongside supporting the use of CCTP for rehabilitating cognitive functions, the present results shed light on how different methodological choices are able to shape research findings in the field of children&#039;s cognitive rehabilitation. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - Oldrati, Viola: viola.oldrati@lanostrafamiglia.itOldrati, Viola, viola.oldrati@lanostrafamiglia.itOldrati, Viola: Scientific Institute, IRCCS E. Medea, Lecco, ItalyCorti, Claudia: Scientific Institute, IRCCS E. Medea, Lecco, ItalyPoggi, Geraldina: Scientific Institute, IRCCS E. Medea, Lecco, ItalyBorgatti, Renato: Scientific Institute, IRCCS E. Medea, Lecco, ItalyUrgesi, Cosimo: Scientific Institute, IRCCS E. Medea, Lecco, ItalyBardoni, Alessandra: Scientific Institute, IRCCS E. Medea, Lecco, Italy
AN  - 2020-15466-001
AU  - Oldrati,
AU  - V.
AU  - Corti,
AU  - C.
AU  - Poggi,
AU  - G.
AU  - Borgatti,
AU  - R.
AU  - Urgesi,
AU  - C.
AU  - Bardoni,
AU  - A.
DA  - Mar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s11065-020-09429-5
DP  - Ovid Technologies
KW  - Cognitive training, Computer-based, Children, Neurodevelopmental disorder, Videogame, Rehabilitation
KW  - *Childhood Development
KW  - *Cognitive Ability
KW  - *Cognitive Rehabilitation
KW  - *Computer Assisted Instruction
KW  - *Brain Training
KW  - Computer Games
KW  - Reinforcement
KW  - Rewards
KW  - Neurological Disorders &amp; Brain Damage [3297]
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://2110373802/Oldrati-2020.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
SP  - 126-141
T2  - Neuropsychology Review
TI  - Effectiveness of computerized cognitive training programs (CCTP) with game-like features in children with or without neuropsychological disorders: A meta-analytic investigation
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2020-15466-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs11065-020-09429-5&amp;issn=1040-7308&amp;isbn=&amp;volume=30&amp;issue=1&amp;spage=126&amp;pages=126-141&amp;date=2020&amp;title=Neuropsychology+Review&amp;atitle=Effectiveness+of+computerized+cognitive+training+programs+%28CCTP%29+with+game-like+features+in+children+with+or+without+neuropsychological+disorders%3A+A+meta-analytic+investigation.&amp;aulast=Oldrati&amp;pid=%3Cauthor%3EOldrati%2C+Viola%3C%2Fauthor%3E%3CAN%3E2020-15466-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs11065-020-09429-5
UR  - https://link.springer.com/content/pdf/10.1007/s11065-020-09429-5.pdf
VL  - 30
ER  -
TY  - JOUR
AB  - **Background**: Attention-deficit/hyperactivity disorder (ADHD) is a common pediatric psychiatric disorder. Although mindful exercises (Yoga and Tai Chi) have been increasingly accepted as alternative medicine for ADHD, no meta-analytic review has been conducted on this topic. 

**Objective**: We systematically and critically evaluated the existing literature regarding the effects of the two most widely practiced mindful exercises on ADHD symptoms and social problems in children and adolescents with ADHD. 

**Methods**: Searching literature databases included PubMed, Web of Science, Scope, China National Knowledge Infrastructure and Wanfang. Only randomized controlled trials (RCT) and non-randomized controlled studies (NRS) that investigated the beneficial effects of Yoga and/or Tai Chi for ADHD were included in this review. Two review authors independently performed literature search, data extraction, and study quality assessment. Based on the random-effect model, standardized mean difference (SMD) reflects magnitude of mindful exercises was calculated. 

**Results**: Seven eligible studies (5 RCTs and 2 NRS) were included for meta-analysis. As compared to control groups, mindful exercises showed significant positive effects on attention (SMD = 0.93, 95% CI 0.39 to 1.48, p &lt; 0.001, 12 = 36%), hyperactivity/impulsivity (SMD = 0.93, 95% CI 0.53 to 1.34, p &lt; 0.001, 12 = 60.17%), overall symptoms of ADHD (SMD = 0.84, 95% CI 0.3 to 1.38, p &lt; 0.05, 12 = 54.61%), and social problems (SMD = 0.49, 95% CI -0.01 to 0.98, p &lt; 0.05, 12 = 0%). 

**Conclusions**: Yoga and Tai Chi may have the potential to alleviate the symptoms and social problems among children and adolescents with ADHD. More robust studies with large sample sizes are needed to validate results of the present meta-analytical review.
AN  - WOS:000601405700002
AU  - Zuo,
AU  - E.
AU  - Zhang,
AU  - Y.
AU  - J.
AU  - Yu,
AU  - Q.
AU  - Guo,
AU  - T.
AU  - Y.
AU  - Jiao,
AU  - C.
AU  - Yu,
AU  - Y.
AU  - Muller,
AU  - P.
AU  - Chi,
AU  - X.
AU  - L.
AU  - Hossain,
AU  - M.
AU  - M.
AU  - Yeung,
AU  - A.
AU  - S.
AU  - Muller,
AU  - N.
AU  - G.
AU  - Zou,
AU  - L.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.32604/IJMHP.2020.014552
L1  - internal-pdf://3978707138/Zuo-2020-Mind-Body Exercises (Yoga_Tai Chi) fo.pdf
PY  - 2020
SP  - 221-231
T2  - INTERNATIONAL JOURNAL OF MENTAL HEALTH PROMOTION
TI  - Mind-Body Exercises (Yoga/Tai Chi) for Attention-Deficit/Hyperactivity Disorder: A Quantitative Evidence of Experimental Studies
VL  - 22
ER  -
TY  - JOUR
AB  - **Background**: Physical exercises can affect executive function both acutely and chronically, with different mechanisms for each moment. Currently, only a few reviews have elaborated on the premise that different types of exercises have different mechanisms for improving executive function. Therefore, the primary purpose of our systematic review was to analyze the effects of acute and chronic exercises on executive function in children and adolescents. 

**Objective**: We identified acute and chronic exercise studies and randomized controlled trials (RCTs) of executive function in children and adolescents that reported overall effect, heterogeneity, and publication bias of acute and chronic exercises on executive function. Methods: We searched for RCTs of exercise interventions in children and adolescents from databases including PubMed, Web of Science, Scopus, The Cochrane Library, CNKI (China National Knowledge Infrastructure), and Wanfang, from January 1 2009 to December 31 2019. We performed methodological quality evaluations on the included literature using the Physiotherapy Evidence Database Scale (PEDro) and graded evidence with a meta-analysis using Stata 12.0 software. 

**Results**: In total, 36 RCTs were included (14 acute exercises, 22 chronic exercises); the overall results of the meta-analysis (4,577 students) indicated that acute exercises significantly improved working memory (standardized mean difference (SMD) = -0.72; 95% confidence interval (CI) -0.89 to -0.56; p &lt; 0.001), inhibitory control (SMD = -0.25; 95% CI -0.40 to -0.09; p = 0.002), and cognitive flexibility (SMD = -0.34; 95% CI -0.55 to -0.14; p &lt; 0.005), whereas chronic exercises significantly improved working memory (SMD = -0.54; 95% CI -0.74 to -0.33; p &lt; 0.001), inhibitory control (SMD = -0.30; 95% CI -0.38 to -0.22; p &lt; 0.001), and cognitive flexibility (SMD = -0.34, 95 % CI -0.48 to -0.20, p &lt; 0.001). 

**Conclusion**: Acute and chronic exercises can effectively improve the executive function of children and adolescents. The effects on inhibitory control and cognitive flexibility are considered as small effect sizes, while the effects on working memory are considered as moderate effect size. Limited by the quantity and quality of the included studies, the above conclusions need to be verified with more high-quality studies.
AN  - WOS:000603635100001
AU  - Liu,
AU  - S.
AU  - J.
AU  - Yu,
AU  - Q.
AU  - Li,
AU  - Z.
AU  - M.
AU  - Cunha,
AU  - P.
AU  - M.
AU  - Zhang,
AU  - Y.
AU  - Kong,
AU  - Z.
AU  - W.
AU  - Lin,
AU  - W.
AU  - Chen,
AU  - S.
AU  - T.
AU  - Cai,
AU  - Y.
AU  - J.
DA  - DEC 17
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyg.2020.554915
L1  - internal-pdf://2435205391/Liu-2020.pdf
PY  - 2020
T2  - FRONTIERS IN PSYCHOLOGY
TI  - Effects of Acute and Chronic Exercises on Executive Function in Children and Adolescents: A Systemic Review and Meta-Analysis
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/554915/pubmed-zip/.versions/1/.package-entries/fpsyg-11-554915/fpsyg-11-554915.pdf?sv=2018-03-28&amp;sr=b&amp;sig=npiZ0t8dn5j1%2BQbLZqhV6%2FHuQ3Y6fuQ%2BPNvWxABL%2FsE%3D&amp;se=2021-06-18T08%3A17%3A39Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyg-11-554915.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - Cognitive-behavioral therapy (CBT) is regarded as an effective treatment for anxiety disorders in childhood. Researchers have begun to investigate potential mechanisms of change that drive these positive outcomes, including shifts in cognitions, behavior, and affect. However, few studies have established the mediational effects of these factors as a proxy for establishing mechanistic change. This meta-analysis attempts to synthesize the literature on potential mechanisms of change in CBT for childhood anxiety and investigates the mediational effects of these factors on treatment outcomes. Seventeen studies met the inclusion criteria. Across studies, five potential mediators were identified: externalizing difficulties, negative self-talk, coping, fear, and depression. Results indicated that CBT was effective in improving outcomes on all potential mediators, except for fear. Mediational analyses showed that externalizing difficulties, negative self-talk, coping, and depression mediated anxiety following treatment. Fear did not mediate the relationship. Implications for future mechanisms of change research are proposed.
AD  - Luo, Aileen. Discipline of Clinical Psychology, Graduate School of Health, University of Technology Sydney, NSW, Australia.Luo, Aileen. Department of Psychology, Macquarie University, NSW, Australia.McAloon, John. Discipline of Clinical Psychology, Graduate School of Health, University of Technology Sydney, NSW, Australia.
AN  - 33225527
AU  - Luo,
AU  - A.
AU  - McAloon,
AU  - J.
DA  - Nov 22
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/da.23116
DP  - Ovid Technologies
J2  - Depress Anxiety
L1  - internal-pdf://3731912656/Luo-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingNovLuo, AileenMcAloon, John
PY  - 2020
SP  - 22
T2  - Depression &amp; Anxiety
TI  - Potential mechanisms of change in cognitive behavioral therapy for childhood anxiety: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33225527
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33225527&amp;id=doi:10.1002%2Fda.23116&amp;issn=1091-4269&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Depression+%26+Anxiety&amp;atitle=Potential+mechanisms+of+change+in+cognitive+behavioral+therapy+for+childhood+anxiety%3A+A+meta-analysis.&amp;aulast=Luo&amp;pid=%3Cauthor%3ELuo+A%3C%2Fauthor%3E%3CAN%3E33225527%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/10.1002/da.23116
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/da.23116?download=true
VL  - 22
ER  -
TY  - JOUR
AB  - This study aimed to review digital interventions in the treatment of autism spectrum disorder (ASD). A systematic review and meta-analysis was conducted. Nineteen studies were included. The interventions aimed to improve social skills (n = 11), developmental skills (n = 2) and 6 other different targets. Technology used were computer programs (n = 14), tablet apps (n = 3), a robot (n = 1) and an interactive DVD (n = 1). The meta-analysis resulted in an overall effect size (Cohen&#039;s d) of 0.32 [0.12-0.51], indicating a small effect. Heterogeneity between studies was high (I-2 = 100%), limiting the generalization of results. Therefore, we recommend larger RCT studies, and guidelines for the development of trials evaluating digital interventions for ASD, for making comparison of future studies possible. Registration can be found online at Prospero: https://www.crd.york.ac.uk/prospero/, registration no. CRD42020146542.
AN  - WOS:000588283100001
AU  - Sandgreen,
AU  - H.
AU  - Frederiksen,
AU  - L.
AU  - H.
AU  - Bilenberg,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s10803-020-04778-9
L1  - internal-pdf://1296008916/Sandgreen.pdf
N1  - Sandgreen, Helena Frederiksen, Line Hofmann Bilenberg, Niels1573-3432
PY  - 2020
T2  - Journal of Autism and Developmental Disorders
TI  - Digital Interventions for Autism Spectrum Disorder: A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000588283100001
UR  - https://link.springer.com/article/10.1007%2Fs10803-020-04778-9
UR  - https://link.springer.com/content/pdf/10.1007/s10803-020-04778-9.pdf
ER  -
TY  - JOUR
AB  - AIM: 
To systematically examine the effectiveness of music therapy on preterm infants in neonatal intensive care unit.

BACKGROUND: 
In recent years, the application of music therapy for preterm infants in neonatal intensive care unit has attracted more and more attention because of its clinical effects. However, there still exist disputes among different studies.

DESIGN: 
A systematic review and meta-analysis.

DATA SOURCES: 
Eleven databases were searched over the period from 1910 -4 November 2019.

REVIEW METHODS: 
Papers were selected for analysis in accordance with the PRISMA guidelines. The meta-analysis was carried out by using Review Manager 5.3 software.

RESULTS: 
A total of 13 trials involving 1,093 participants were included. Meta-analysis showed music therapy had a significant influence on preterm infant&#039;s heart rate, respiratory rate, oral feeding volume, stress level, and maternal anxiety with moderate-to-high heterogeneity among studies. Also, music therapy had no influences on oxygen saturation and behavioural state.

CONCLUSIONS: 
Music therapy can not only effectively improve preterm infant&#039;s heart rate, stable respiratory rate, and attenuate stress level but also exert positive impact on oral feeding volume. In addition, music therapy also plays a role in reducing maternal anxiety. However, due to the heterogeneity across studies in some outcomes, further studies with larger sample size and more stringent design should be conducted before recommendation.IMPACT: Music therapy can significantly improve preterm infant&#039;s heart rate, respiratory rate, and stress level, as well as increase oral feeding volume. These results may exert a positive impact on well-being and quality of life in preterm infants in the neonatal intensive care unit. Hospitals can apply music therapy which has been considered a non-pharmacological and no-invasive treatment to preterm infants in the neonatal intensive care unit.
AD  - Yue, Wei. School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, China.Han, Xinrui. School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, China.Luo, Jianghe. School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, China.Zeng, Zhumei. School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, China.Yang, Ming. School of Nursing, Guangzhou University of Chinese Medicine, Guangzhou, China.Yang, Ming. Guangzhou University City, Guangzhou, China.
AN  - 33200833
AU  - Yue,
AU  - W.
AU  - Han,
AU  - X.
AU  - Luo,
AU  - J.
AU  - Zeng,
AU  - Z.
AU  - Yang,
AU  - M.
DA  - Nov 17
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jan.14630
DP  - Ovid Technologies
J2  - J Adv Nurs
L1  - internal-pdf://0519219051/Yue-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingNovYue, WeiHan, XinruiLuo, JiangheZeng, ZhumeiYang, Ming
PY  - 2020
SP  - 17
T2  - Journal of Advanced Nursing
TI  - Effect of music therapy on preterm infants in neonatal intensive care unit: Systematic review and meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33200833
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33200833&amp;id=doi:10.1111%2Fjan.14630&amp;issn=0309-2402&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Journal+of+Advanced+Nursing&amp;atitle=Effect+of+music+therapy+on+preterm+infants+in+neonatal+intensive+care+unit%3A+Systematic+review+and+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Yue&amp;pid=%3Cauthor%3EYue+W%3C%2Fauthor%3E%3CAN%3E33200833%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/10.1111/jan.14630
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jan.14630?download=true
VL  - 17
ER  -
TY  - JOUR
AB  - **Background**
People living in &#039;humanitarian settings&#039; in low‐ and middle‐income countries (LMICs) are exposed to a constellation of physical and psychological stressors that make them vulnerable to developing mental disorders. A range of psychological and social interventions have been implemented with the aim to prevent the onset of mental disorders and/or lower psychological distress in populations at risk, and it is not known whether interventions are effective.

**Objectives**
To compare the efficacy and acceptability of psychological and social interventions versus control conditions (wait list, treatment as usual, attention placebo, psychological placebo, or no treatment) aimed at preventing the onset of non‐psychotic mental disorders in people living in LMICs affected by humanitarian crises.

**Search methods**
We searched the Cochrane Common Mental Disorders Controlled Trials Register (CCMD‐CTR), the Cochrane Drugs and Alcohol Review Group (CDAG) Specialized Register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (OVID), Embase (OVID), PsycINFO (OVID), and ProQuest PILOTS database with results incorporated from searches to February 2020. We also searched the World Health Organization&#039;s (WHO) International Clinical Trials Registry Platform and ClinicalTrials.gov to identify unpublished or ongoing studies. We checked the reference lists of relevant studies and reviews.

**Selection criteria**
All randomised controlled trials (RCTs) comparing psychological and social interventions versus control conditions to prevent the onset of mental disorders in adults and children living in LMICs affected by humanitarian crises. We excluded studies that enrolled participants based on a positive diagnosis of mental disorder (or based on a proxy of scoring above a cut‐off score on a screening measure).

**Data collection and analysis**
We calculated standardised mean differences for continuous outcomes and risk ratios for dichotomous data, using a random‐effects model. We analysed data at endpoint (zero to four weeks after therapy) and at medium term (one to four months after intervention). No data were available at long term (six months or longer). We used GRADE to assess the quality of evidence.

**Main results**
In the present review we included seven RCTs with a total of 2398 participants, coming from both children/adolescents (five RCTs), and adults (two RCTs). Together, the seven RCTs compared six different psychosocial interventions against a control comparator (waiting list in all studies). All the interventions were delivered by paraprofessionals and, with the exception of one study, delivered at a group level.None of the included studies provided data on the efficacy of interventions to prevent the onset of mental disorders (incidence). For the primary outcome of acceptability, there may be no evidence of a difference between psychological and social interventions and control at endpoint for children and adolescents (RR 0.93, 95% CI 0.78 to 1.10; 5 studies, 1372 participants; low‐quality evidence) or adults (RR 0.96, 95% CI 0.61 to 1.50; 2 studies, 767 participants; very low quality evidence). No information on adverse events related to the interventions was available.For children&#039;s and adolescents&#039; secondary outcomes of prevention interventions, there may be no evidence of a difference between psychological and social intervention groups and control groups for reducing PTSD symptoms (standardised mean difference (SMD) &minus;0.16, 95% CI &minus;0.50 to 0.18; 3 studies, 590 participants; very low quality evidence), depressive symptoms (SMD &minus;0.01, 95% CI &minus;0.29 to 0.31; 4 RCTs, 746 participants; very low quality evidence) and anxiety symptoms (SMD 0.11, 95% CI &minus;0.09 to 0.31; 3 studies, 632 participants; very low quality evidence) at study endpoint.In adults&#039; secondary outcomes of prevention interventions, psychological counselling may be effective for reducing depressive symptoms (MD &minus;7.50, 95% CI &minus;9.19 to &minus;5.81; 1 study, 258 participants; very low quality evidence) and anxiety symptoms (MD &minus;6.10, 95% CI &minus;7.57 to &minus;4.63; 1 study, 258 participants; very low quality evidence) at endpoint. No data were available for PTSD symptoms in the adult population.Owing to the small number of RCTs included in the present review, it was not possible to carry out neither sensitivity nor subgroup analyses.

**Authors&#039; conclusions**
Of the seven prevention studies included in this review, none assessed whether prevention interventions reduced the incidence of mental disorders and there may be no evidence for any differences in acceptability. Additionally, for both child and adolescent populations and adult populations, a very small number of RCTs with low quality evidence on the review&#039;s secondary outcomes (changes in symptomatology at endpoint) did not suggest any beneficial effect for the studied prevention interventions.Confidence in the findings is hampered by the scarcity of prevention studies eligible for inclusion in the review, by risk of bias in the studies, and by substantial levels of heterogeneity. Moreover, it is possible that random error had a role in distorting results, and that a more thorough picture of the efficacy of prevention interventions will be provided by future studies. For this reason, prevention studies are urgently needed to assess the impact of interventions on the incidence of mental disorders in children and adults, with extended periods of follow‐up.
AU  - Papola,
AU  - D.
AU  - Purgato,
AU  - M.
AU  - Gastaldon,
AU  - C.
AU  - Bovo,
AU  - C.
AU  - van
AU  - Ommeren,
AU  - M.
AU  - Barbui,
AU  - C.
AU  - Tol,
AU  - W.
AU  - A.
DA  - September
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD012417.pub2
L1  - internal-pdf://3668207139/Papola_et_al-2020-Cochrane_Database_of_Systema.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological and social interventions for the prevention of mental disorders in people living in low- and middle-income countries affected by humanitarian crises
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering og klassifisering av foreldreprogrammet De Utrolige Årene (DUÅ), rettet mot førskolebarn (3-6 år) og barn i skolealder (6-12 år). Foreldreprogrammene er rettet mot foreldre til barn med atferdsproblemer på et forebyggende, selektert, eller indikert nivå. Det vil si, programmene kan tilrettelegges som enten forebyggende tiltak eller behandlingstiltak. Foreldreprogrammene er utviklet av Carolyn Webster-Stratton, USA. I Norge er det Regionalt Kunnskapssenter for Barn og Unge &ndash; Nord (RKBU Nord) som er tiltaksleverandør og har det nasjonale ansvaret for opplæring.

METODE
Kunnskapsoppsummeringen bygger på et systematisk litteratursøk fra ulike databaser (Embase, Medline, Psykinfo, NORART, Cochrane, Cristin, NORA, Scopus, SweMed, Bibsys, og Google Scholar), samt materiell gitt fra tiltakseier. Søket ble gjennomgått for å identifisere internasjonale, nordiske og norske effektstudier om tiltakene. Ni nordiske artikler (3 norske, 4 svenske,1 dansk og 1 finsk), samt tre internasjonale meta-analyser, er evaluert og inkludert i kunnskapsoppsummeringen.

RESULTATER
Resultatene viser at DUÅs foreldreprogrammer er kunnskaps- og evidensbaserte tiltak med solid teoretisk forankring. De baserer seg på etablerte måleinstrumenter, og tiltakene har godt beskrevne implementeringsstrategier. Samtlige av de nordiske studiene viste positive resultater til fordel for de to programmene, det vil si en reduksjon i barns problematferd og en positiv endring i foreldre-barn samspill.

KONKLUSJON
DUÅs foreldreprogrammer for førskole- og skolebarn klassifiseres på evidensnivå 5, det vil si tiltak med sterk dokumentasjon på effekt.
AU  - Hukkelberg,
AU  - S.,
AU  - Torsheim,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2020
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: De Utrolige Årene (DUÅ): Foreldreprogram for Førskolebarn (3-6 år) og Skolebarn (6-12 år) (2.utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/de-utrolige-arene-dua-foreldreprogram-for-forskolebarn-3-6-ar-og-skolebarn-6-12-ar/
VL  - 2
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Postpartum depression is common in the perinatal period and poses a risk for the development of the infant and the mother-infant relationship. Infancy is a critical developmental period of life and supportive parenting is crucial for healthy development, however, the effects of interventions aimed at improving parenting among mothers with depression are uncertain.AIMS: To assess the effects of parenting interventions on parent-child relationship and child development among mothers with depressive symptoms with 0-12-month-old infants.

METHOD: 
We conducted a systematic review with the inclusion criteria: (a) randomised controlled trials of structured psychosocial parenting interventions for women with depressive symptoms and a child aged 0-12 months in Western Organisation for Economic Co-operation and Development countries, (b) minimum three sessions with at least half of these delivered postnatally and (c) outcomes relating to the parent-child-relationship and/or child development. Publications were extracted from 10 databases in September 2018 and supplemented with grey search and hand search. We assessed risk of bias, calculated effect sizes and conducted meta-analysis.

RESULTS: 
Eight papers representing seven trials were included. We conducted meta-analysis on the post-intervention parent-child relationship. The analysis included six studies and showed no significant effect. For individual study outcomes, no significant effects on the majority of both the parent-child relationship and child development outcomes were reported.

CONCLUSIONS: 
No evidence of the effect of parenting interventions for mothers with depressive symptoms was found on the parent-child relationship and child development. Larger studies with follow-up assessments are needed, and future reviews should examine the effects in non-Western countries.
AD  - Rayce, Signe B. Senior Researcher, VIVE - The Danish Center for Social Science Research, Denmark.Rasmussen, Ida S. Research Assistant, VIVE - The Danish Center for Social Science Research, Denmark.Vaever, Mette Skovgaard. Associate Professor, Department of Psychology, University of Copenhagen, Denmark.Pontoppidan, Maiken. Senior Researcher, VIVE - The Danish Center for Social Science Research, Denmark.
AN  - 31928569
AU  - Rayce,
AU  - S.
AU  - B.
AU  - Rasmussen,
AU  - I.
AU  - S.
AU  - Vaever,
AU  - M.
AU  - S.
AU  - Pontoppidan,
AU  - M.
DA  - Jan 13
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1192/bjo.2019.89
DP  - Ovid Technologies
J2  - BJPsych Open
L1  - internal-pdf://0268741516/Rayce-2020-Effects of parenting interventions.pdf
LA  - English
N1  - Rayce, Signe BRasmussen, Ida SVaever, Mette SkovgaardPontoppidan, Maiken
PY  - 2020
SP  - e9
T2  - BJPsych Open
TI  - Effects of parenting interventions for mothers with depressive symptoms and an infant: systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31928569
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31928569&amp;id=doi:10.1192%2Fbjo.2019.89&amp;issn=2056-4724&amp;isbn=&amp;volume=6&amp;issue=1&amp;spage=e9&amp;pages=e9&amp;date=2020&amp;title=BJPsych+Open&amp;atitle=Effects+of+parenting+interventions+for+mothers+with+depressive+symptoms+and+an+infant%3A+systematic+review+and+meta-analysis.&amp;aulast=Rayce&amp;pid=%3Cauthor%3ERayce+SB%3C%2Fauthor%3E%3CAN%3E31928569%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/BD65D9E48BA6CABB4BB8FEDCB41358A9/S2056472419000899a.pdf/div-class-title-effects-of-parenting-interventions-for-mothers-with-depressive-symptoms-and-an-infant-systematic-review-and-meta-analysis-div.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - OBJECTIVES: Rates of psychiatric disorders are considerably elevated in young people with long term physical health conditions. Currently few children obtain effective mental health treatments in the context of long term physical health conditions, and ways to improve access to evidence-based mental health interventions are urgently needed. One approach is to deploy briefer, more economical, yet still evidence-based, treatments. The objective of this review was to evaluate the efficacy of brief interventions targeting psychiatric disorders in children and young people with long term physical health conditions.

METHODS: Predefined terms relating to brief psychological interventions for psychiatric disorders in children with long term physical health conditions were used to search relevant databases. A systematic review and meta-analysis was carried out in accordance with the Cochrane guidelines. Two reviewers independently screened titles and abstracts, extracted the data and conducted risk of bias assessments.

RESULTS: A total of 12 randomised controlled trials were found to meet the inclusion criteria of the review. Of those, three studies were suitable for meta-analysis. A large effect size in favour of brief cognitive behavioural therapy for anxiety was found (g = - 0.95, CI -1.49 to -0.041; p &lt; .001) with non-significant moderate-substantial heterogeneity (I&lt;sup&gt;2&lt;/sup&gt; = 58%; p = .09).

CONCLUSION: This review suggests there is preliminary evidence that brief interventions, based on cognitive behavioural principles, may benefit young people with an anxiety disorder in the context of a long term physical health condition. There was insufficient evidence to assess whether this held true for depression and disruptive behaviour.
AD  - Catanzano, M. Great Ormond Street Hospital NHS Foundation Trust, Great Ormond Street, London, UK; UCL Great Ormond Street Institute of Child Health, London, UK. Electronic address: matteo.catanzano@nhs.net.Bennett, S D. Great Ormond Street Hospital NHS Foundation Trust, Great Ormond Street, London, UK; UCL Great Ormond Street Institute of Child Health, London, UK.Sanderson, C. UCL Great Ormond Street Institute of Child Health, London, UK.Patel, M. Great Ormond Street Hospital NHS Foundation Trust, Great Ormond Street, London, UK; UCL Great Ormond Street Institute of Child Health, London, UK.Manzotti, G. UCL Great Ormond Street Institute of Child Health, London, UK.Kerry, E. Great Ormond Street Hospital NHS Foundation Trust, Great Ormond Street, London, UK; UCL Great Ormond Street Institute of Child Health, London, UK.Coughtrey, A E. Great Ormond Street Hospital NHS Foundation Trust, Great Ormond Street, London, UK; UCL Great Ormond Street Institute of Child Health, London, UK.Liang, H. Great Ormond Street Hospital NHS Foundation Trust, Great Ormond Street, London, UK; UCL Great Ormond Street Institute of Child Health, London, UK.Heyman, I. Great Ormond Street Hospital NHS Foundation Trust, Great Ormond Street, London, UK; UCL Great Ormond Street Institute of Child Health, London, UK.Shafran, R. Great Ormond Street Hospital NHS Foundation Trust, Great Ormond Street, London, UK; UCL Great Ormond Street Institute of Child Health, London, UK.
AN  - 32688073
AU  - Catanzano,
AU  - M.
AU  - Bennett,
AU  - S.
AU  - D.
AU  - Sanderson,
AU  - C.
AU  - Patel,
AU  - M.
AU  - Manzotti,
AU  - G.
AU  - Kerry,
AU  - E.
AU  - Coughtrey,
AU  - A.
AU  - E.
AU  - Liang,
AU  - H.
AU  - Heyman,
AU  - I.
AU  - Shafran,
AU  - R.
DA  - Jul 06
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jpsychores.2020.110187
DP  - Ovid Technologies
J2  - J Psychosom Res
L1  - internal-pdf://1281720104/Catanzano.pdf
LA  - English
M3  - Review
N1  - Catanzano, MBennett, S DSanderson, CPatel, MManzotti, GKerry, ECoughtrey, A ELiang, HHeyman, IShafran, RS0022-3999(20)30749-2
PY  - 2020
SP  - 110187
T2  - Journal of Psychosomatic Research
TI  - Brief psychological interventions for psychiatric disorders in young people with long term physical health conditions: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32688073
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32688073&amp;id=doi:10.1016%2Fj.jpsychores.2020.110187&amp;issn=0022-3999&amp;isbn=&amp;volume=136&amp;issue=&amp;spage=110187&amp;pages=110187&amp;date=2020&amp;title=Journal+of+Psychosomatic+Research&amp;atitle=Brief+psychological+interventions+for+psychiatric+disorders+in+young+people+with+long+term+physical+health+conditions%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Catanzano&amp;pid=%3Cauthor%3ECatanzano+M%3C%2Fauthor%3E%3CAN%3E32688073%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 136
ER  -
TY  - JOUR
AB  - **Background**
Previous Cochrane Reviews have shown that cognitive behavioural therapy (CBT) is effective in treating childhood anxiety disorders. However, questions remain regarding the following: up‐to‐date evidence of the relative efficacy and acceptability of CBT compared to waiting lists/no treatment, treatment as usual, attention controls, and alternative treatments; benefits across a range of outcomes; longer‐term effects; outcomes for different delivery formats; and amongst children with autism spectrum disorders (ASD) and children with intellectual impairments.

**Objectives**
To examine the effect of CBT for childhood anxiety disorders, in comparison with waitlist/no treatment, treatment as usual (TAU), attention control, alternative treatment, and medication.

**Search methods**
We searched the Cochrane Common Mental Disorders Controlled Trials Register (all years to 2016), the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, and PsycINFO (each to October 2019), international trial registries, and conducted grey literature searches.Selection criteriaWe included randomised controlled trials of CBT that involved direct contact with the child, parent, or both, and included non‐CBT comparators (waitlist/no treatment, treatment as usual, attention control, alternative treatment, medication). Participants were younger than age 19, and met diagnostic criteria for an anxiety disorder diagnosis. Primary outcomes were remission of primary anxiety diagnosis post‐treatment, and acceptability (number of participants lost to post‐treatment assessment), and secondary outcomes included remission of all anxiety diagnoses, reduction in anxiety symptoms, reduction in depressive symptoms, improvement in global functioning, adverse effects, and longer‐term effects.Data collection and analysisWe used standard methodological procedures as recommended by Cochrane. We used GRADE to assess the quality of the evidence.

**Main results**
We included 87 studies and 5964 participants in quantitative analyses.

Compared with waitlist/no treatment, CBT probably increases post‐treatment remission of primary anxiety diagnoses (CBT: 49.4%, waitlist/no treatment: 17.8%; OR 5.45, 95% confidence interval (CI) 3.90 to 7.60; n = 2697, 39 studies, moderate quality); NNTB 3 (95% CI 2.25 to 3.57) and all anxiety diagnoses (OR 4.43, 95% CI 2.89 to 6.78; n = 2075, 28 studies, moderate quality).

Low‐quality evidence did not show a difference between CBT and TAU in post‐treatment primary anxiety disorder remission (OR 3.19, 95% CI 0.90 to 11.29; n = 487, 8 studies), but did suggest CBT may increase remission from all anxiety disorders compared to TAU (OR 2.74, 95% CI 1.16 to 6.46; n = 203, 5 studies).

Compared with attention control, CBT may increase post‐treatment remission of primary anxiety disorders (OR 2.28, 95% CI 1.33 to 3.89; n = 822, 10 studies, low quality) and all anxiety disorders (OR 2.75, 95% CI 1.22 to 6.17; n = 378, 5 studies, low quality).

There was insufficient available data to compare CBT to alternative treatments on post‐treatment remission of primary anxiety disorders, and low‐quality evidence showed there may be little to no difference between these groups on post‐treatment remission of all anxiety disorders (OR 0.89, 95% CI 0.35 to 2.23; n = 401, 4 studies).

Low‐quality evidence did not show a difference for acceptability between CBT and waitlist/no treatment (OR 1.09, 95% CI 0.85 to 1.41; n=3158, 45 studies), treatment as usual (OR 1.37, 95% CI 0.73 to 2.56; n = 441, 8 studies), attention control (OR 1.00, 95% CI 0.68 to 1.49; n = 797, 12 studies) and alternative treatment (OR 1.58, 95% CI 0.61 to 4.13; n=515, 7 studies).

No adverse effects were reported across all studies; however, in the small number of studies where any reference was made to adverse effects, it was not clear that these were systematically monitored.

Results from the anxiety symptom outcomes, broader outcomes, longer‐term outcomes and subgroup analyses are provided in the text.

We did not find evidence of consistent differences in outcomes according to delivery formats (e.g. individual versus group; amount of therapist contact time) or amongst samples with and without ASD, and no studies included samples of children with intellectual impairments.

**Authors&#039; conclusions**
CBT is probably more effective in the short‐term than waiting lists/no treatment, and may be more effective than attention control. We found little to no evidence across outcomes that CBT is superior to usual care or alternative treatments, but our confidence in these findings are limited due to concerns about the **amount and quality of available evidence, and we still know little about how best to efficiently improve outcomes.
AU  - James.
AU  - A.
AU  - C.
AU  - Reardon,
AU  - T.
AU  - Soler,
AU  - A.
AU  - James,
AU  - G.
AU  - Creswell,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013162.pub2
L1  - internal-pdf://4015472054/James_et_al-2020-Cochrane_Database_of_Systemat.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive behavioural therapy for anxiety disorders in children and adolescents
ER  -
TY  - JOUR
AB  - Lack of preformed long-chain polyunsaturated fatty acids (LCPUFA) in infant formula has been hypothesised as contributing to cognitive differences between breast-fed and formulafed infants. Previous systematic reviews found no cognitive differences between infants fed formula with LCPUFA and those fed formula without, but focused on early developmental measures, such as Bayley Scales of Infant Development, which are poorly differentiating and not predictive of cognitive ability in childhood. This systematic review examined the effect of randomising infants to formula supplemented with LCUFA vs unsupplemented formula on cognitive function &gt;= age 2.5 years. We searched Medline, Embase the Cochrane Central Register of Controlled Trials without date limit, following a pre-published protocol according to PRISMA guidelines. We conducted random effects meta-analyses in RevMan v5.4 and followed GRADE and Cochrane Guidelines to evaluate strength of evidence and potential for bias. We included 8 trial cohorts which randomised participants between 1993 and 2004 and analyse 6 previously unpublished outcomes provided by various trialists. Age at the last available cognitive test ranged from 3.3 to 16 years. The pooled mean difference in Wechsler Preschool and Primary Scale of Intelligence-Revised from four trials in termborn children showed no benefit of LCPUFA: -0.04 points (95% confidence interval -5.94 to 5.85, 95% prediction interval -14.17 to 14.25). The pooled mean difference in Wechsler Abbreviated Scale of Intelligence score from two trials in preterm-born children also showed no benefit of LCPUFA: -7.71 (95% CI -24.63 to 9.22, 95% PI -97.80 to 82.38). Overall quality of evidence was low, due to substantial heterogeneity, low rates of follow-up, and indications of selective publication. The long-term effect of LCPUFA supplementation in term and preterm- born infants on cognition is highly uncertain and includes potential for large benefit as well as large harm. Based on our findings, LCPUFA supplementation of infant formula is not recommended until further robust evidence excludes long-term harm. Copyright &copy; 2020 Verfuerden et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AD  - (Verfuerden, Dib, Fewtrell, Gilbert) University College London Great Ormond Street, Institute of Child Health, London, United Kingdom (Jerrim) University College London, Institute of Education, London, United Kingdom (Gilbert) Health Data Research UK, London, United KingdomM.L. Verfuerden, University College London Great Ormond Street, Institute of Child Health, London, United Kingdom. E-mail: m.verfuerden@ucl.ac.uk
AN  - 2008510164
AU  - Verfuerden,
AU  - M.
AU  - L.
AU  - Dib,
AU  - S.
AU  - Jerrim,
AU  - J.
AU  - Fewtrell,
AU  - M.
AU  - Gilbert,
AU  - R.
AU  - E.
DA  - Nov
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0241800
DP  - Ovid Technologies
KW  - adolescent
KW  - article
KW  - artificial milk
KW  - child
KW  - childhood
KW  - Cochrane Library
KW  - cognition
KW  - cohort analysis
KW  - controlled study
KW  - Embase
KW  - female
KW  - follow up
KW  - human
KW  - human experiment
KW  - infant
KW  - male
KW  - Medline
KW  - meta analysis
KW  - prediction
KW  - Preferred Reporting Items for Systematic Reviews and Meta-Analyses
KW  - randomized controlled trial (topic)
KW  - systematic review
KW  - Wechsler preschool and primary scale of intelligence
L1  - internal-pdf://0077767134/Verfuerden-2020-Effect of long-chain polyunsat.pdf
LA  - English
PY  - 2020
T2  - PLoS ONE
TI  - Effect of long-chain polyunsaturated fatty acids in infant formula on long-term cognitive function in childhood: A systematic review and meta-analysis of randomised controlled trials
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0241800&amp;type=printable
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2008510164
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33152012&amp;id=doi:10.1371%2Fjournal.pone.0241800&amp;issn=1932-6203&amp;isbn=&amp;volume=15&amp;issue=11+November&amp;spage=e0241800&amp;pages=&amp;date=2020&amp;title=PLoS+ONE&amp;atitle=Effect+of+long-chain+polyunsaturated+fatty+acids+in+infant+formula+on+long-term+cognitive+function+in+childhood%3A+A+systematic+review+and+meta-analysis+of+randomised+controlled+trials&amp;aulast=Verfuerden&amp;pid=%3Cauthor%3EVerfuerden+M.L.%3C%2Fauthor%3E%3CAN%3E2008510164%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
VL  - 15 (11 November) (no pagination)
ER  -
TY  - JOUR
AB  - PURPOSE: High-intensity interval training (HIIT) has emerged as a time-efficient strategy to improve children and adolescents&#039; health-related fitness in comparison to traditional training methods. However, little is known regarding the effects on cognitive function and mental health. Therefore, the aim of this systematic review was to evaluate the effect of HIIT on cognitive function (basic information processing, executive function) and mental health (well-being, ill-being) outcomes for children and adolescents.

METHODS: A systematic search as conducted, and studies were eligible if they: (1) included a high-intensity interval training protocol: (2) examined cognitive function or mental health outcomes; (3) examined children or adolescents (5-18 years). Separate meta-analyses were conducted for acute and chronic studies, with potential moderators (i.e., study duration, risk of bias, participant age, cognitive demand, and study population) also explored.

RESULTS: A total of 22 studies were included in the review. In acute studies, small to moderate effects were found for executive function (SMD = 0.50, 95% CI 0.03 to 0.98, p = .038) and affect (SMD = 0.33, 95% CI 0.05 to 0.62, p = .020), respectively. For chronic studies, small significant effects were found for executive function (SMD = 0.31, 95% CI 0.15 to 0.76, p &lt;.001), well-being (SMD = 0.22, 95% CI 0.02 to 0.41, p = .029), and ill-being (SMD = -0.35, 95% CI -0.68 to -0.03, p =.035).

CONCLUSIONS: Our review provides preliminary review evidence suggesting that participation in HIIT can improve cognitive function and mental health in children and adolescents. Due to the small number of studies and large heterogeneity, more high-quality research is needed to confirm these findings.
AD  - Leahy, Angus A. Priority Research Centre for Physical Activity and Nutrition, Faculty of Education and Arts, University of Newcastle, Callaghan, New South Wales, Australia.Mavilidi, Myrto F. Priority Research Centre for Physical Activity and Nutrition, Faculty of Education and Arts, University of Newcastle, Callaghan, New South Wales, Australia.Smith, Jordan J. Priority Research Centre for Physical Activity and Nutrition, Faculty of Education and Arts, University of Newcastle, Callaghan, New South Wales, Australia.Hillman, Charles H. Department of Psychology, Northeastern University, Boston, MA.Hillman, Charles H. Department of Physical Therapy, Movement and Rehabilitation Sciences, Northeastern University, Boston, MA.Eather, Narelle. Priority Research Centre for Physical Activity and Nutrition, Faculty of Education and Arts, University of Newcastle, Callaghan, New South Wales, Australia.Barker, Daniel. Faculty of Health and Medicine, School of Medicine and Public Health, University of Newcastle, Callaghan, New South Wales, Australia.Lubans, David R. Priority Research Centre for Physical Activity and Nutrition, Faculty of Education and Arts, University of Newcastle, Callaghan, New South Wales, Australia.
AN  - 32301856
AU  - Leahy,
AU  - A.
AU  - A.
AU  - Mavilidi,
AU  - M.
AU  - F.
AU  - Smith,
AU  - J.
AU  - J.
AU  - Hillman,
AU  - C.
AU  - H.
AU  - Eather,
AU  - N.
AU  - Barker,
AU  - D.
AU  - Lubans,
AU  - D.
AU  - R.
DA  - Apr 13
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1249/MSS.0000000000002359
DP  - Ovid Technologies
J2  - Med Sci Sports Exerc
L1  - internal-pdf://1908653603/Leahy-2020.pdf
LA  - English
N1  - Using Smart Source ParsingAprLeahy, Angus AMavilidi, Myrto FSmith, Jordan JHillman, Charles HEather, NarelleBarker, DanielLubans, David R
PY  - 2020
T2  - Medicine &amp; Science in Sports &amp; Exercise
TI  - Review of High-Intensity Interval Training for Cognitive and Mental Health in Youth
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32301856
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32301856&amp;id=doi:10.1249%2FMSS.0000000000002359&amp;issn=0195-9131&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=&amp;date=2020&amp;title=Medicine+%26+Science+in+Sports+%26+Exercise&amp;atitle=Review+of+High-Intensity+Interval+Training+for+Cognitive+and+Mental+Health+in+Youth.&amp;aulast=Leahy&amp;pid=%3Cauthor%3ELeahy+AA%3C%2Fauthor%3E%3CAN%3E32301856%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 13
ER  -
TY  - JOUR
AB  - BACKGROUND: Interest in delivering psychological interventions within schools to facilitate early intervention is increasing. However, most reviews have focused on universal or preventative programmes rather than interventions designed to decrease existing symptoms of depression or anxiety. This paper aims to provide a meta-analytic review of randomised controlled trials of indicated psychological interventions for young people aged 10-19 with elevated symptoms of depression and/or anxiety.

METHODS: Eight electronic databases were systematically searched from inception to April 2019 for eligible trials. Study quality was assessed using two scales designed to evaluate psychotherapy intervention trials. Random effects meta-analyses were conducted separately for trials that recruited participants based on symptoms of depression and based on symptoms of anxiety.

RESULTS: Data from 45 trials were analysed. Most interventions studied used cognitive and behavioural strategies. Few studies met methodological quality criteria, but effect size was not associated with study quality. Indicated school-based interventions had a small effect on reducing depression symptoms (SMD = .34, 95% CI -0.48, -0.21) and a medium effect on reducing anxiety symptoms (SMD = -.49, 95% CI -0.79, -0.19) immediately postintervention. Subgroup analyses indicated that interventions delivered by internal school staff did not have significant effects on symptoms. Reductions in depression were maintained at short-term (&lt;=6 months) but not medium (&gt;6 months &lt;= 12) or long-term (&gt;12-month) follow-up. Reductions in anxiety symptoms were not maintained at any follow-up.

CONCLUSIONS: Indicated school-based interventions are effective at reducing symptoms of depression and anxiety in adolescents immediately postintervention but there is little evidence that these reductions are maintained. Interventions delivered by school staff are not supported by the current evidence base. Further high-quality randomised controlled trials incorporating assessment of longer-term outcomes are needed to justify increased investment in school-based interventions for adolescent depression and anxiety.
AD  - Gee, Brioney. Research &amp; Development Department, Norfolk and Suffolk NHS Foundation Trust, Norwich, UK.Gee, Brioney. Norwich Medical School, University of East Anglia, Norwich, UK.Reynolds, Shirley. School of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.Carroll, Ben. Research &amp; Development Department, Norfolk and Suffolk NHS Foundation Trust, Norwich, UK.Orchard, Faith. School of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.Clarke, Tim. Research &amp; Development Department, Norfolk and Suffolk NHS Foundation Trust, Norwich, UK.Clarke, Tim. Norwich Medical School, University of East Anglia, Norwich, UK.Martin, David. Research &amp; Development Department, Norfolk and Suffolk NHS Foundation Trust, Norwich, UK.Wilson, Jon. Research &amp; Development Department, Norfolk and Suffolk NHS Foundation Trust, Norwich, UK.Wilson, Jon. Norwich Medical School, University of East Anglia, Norwich, UK.Pass, Laura. Norwich Medical School, University of East Anglia, Norwich, UK.Pass, Laura. School of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.
AN  - 32250447
AU  - Gee,
AU  - B.
AU  - Reynolds,
AU  - S.
AU  - Carroll,
AU  - B.
AU  - Orchard,
AU  - F.
AU  - Clarke,
AU  - T.
AU  - Martin,
AU  - D.
AU  - Wilson,
AU  - J.
AU  - Pass,
AU  - L.
DA  - Apr 06
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13209
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
L1  - internal-pdf://2081602935/Gee-2020.pdf
LA  - English
N1  - Using Smart Source ParsingAprGee, BrioneyReynolds, ShirleyCarroll, BenOrchard, FaithClarke, TimMartin, DavidWilson, JonPass, Laura
PY  - 2020
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Practitioner Review: Effectiveness of indicated school-based interventions for adolescent depression and anxiety - a meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32250447
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32250447&amp;id=doi:10.1111%2Fjcpp.13209&amp;issn=0021-9630&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Practitioner+Review%3A+Effectiveness+of+indicated+school-based+interventions+for+adolescent+depression+and+anxiety+-+a+meta-analytic+review.&amp;aulast=Gee&amp;pid=%3Cauthor%3EGee+B%3C%2Fauthor%3E%3CAN%3E32250447%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1111/jcpp.13209
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/jcpp.13209
VL  - 06
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Children and adolescents display different symptoms of post-traumatic stress disorder (PTSD) than adults. Whilst evidence for the effectiveness of psychological interventions has been synthesised for adults, this is not directly applicable to younger people. Therefore, this systematic review and meta-analysis synthesised studies investigating the effectiveness of psychological interventions for PTSD in children, adolescents and young adults. It provides an update to previous reviews investigating interventions in children and adolescents, whilst investigating young adults for the first time.

METHODS: 
We searched published and grey literature to obtain randomised control trials assessing psychological interventions for PTSD in young people published between 2011 and 2019. Quality of studies was assessed using the Cochrane Risk of Bias tool. Data were analysed using univariate random-effects meta-analysis.

RESULTS: 
From 15 373 records, 27 met criteria for inclusion, and 16 were eligible for meta-analysis. There was a medium pooled effect size for all psychological interventions (d = -0.44, 95% CI -0.68 to -0.20), as well as for Trauma-Focused Cognitive Behavioural Therapy (TF-CBT) and Eye Movement Desensitisation and Reprocessing (EMDR) (d = -0.30, 95% CI -0.58 to -0.02); d = -0.46, 95% CI -0.81 to -0.12).

CONCLUSIONS: 
Some, but not all, psychological interventions commonly used to treat PTSD in adults were effective in children, adolescents and young adults. Interventions specifically adapted for younger people were also effective. Our results support the National Institute for Health and Care Excellence guidelines which suggest children and adolescents be offered TF-CBT as a first-line treatment because of a larger evidence base, despite EMDR being more effective.
AD  - John-Baptiste Bastien, Rayanne. Division of Psychiatry, UCL, London, England.Jongsma, Hannah E. Division of Psychiatry, UCL, London, England.Kabadayi, Melissa. Division of Psychiatry, UCL, London, England.Billings, Jo. Division of Psychiatry, UCL, London, England.
AN  - 32624017
AU  - John-Baptiste
AU  - Bastien,
AU  - R.
AU  - Jongsma,
AU  - H.
AU  - E.
AU  - Kabadayi,
AU  - M.
AU  - Billings,
AU  - J.
DA  - Jun 22
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1017/S0033291720002007
DP  - Ovid Technologies
J2  - Psychol Med
L1  - internal-pdf://3923214870/John-Baptiste Bastien-2020.pdf
LA  - English
N1  - John-Baptiste Bastien, RayanneJongsma, Hannah EKabadayi, MelissaBillings, Jo
PY  - 2020
SP  - 1-15
T2  - Psychological Medicine
TI  - The effectiveness of psychological interventions for post-traumatic stress disorder in children, adolescents and young adults: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32624017
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32624017&amp;id=doi:10.1017%2FS0033291720002007&amp;issn=0033-2917&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-15&amp;date=2020&amp;title=Psychological+Medicine&amp;atitle=The+effectiveness+of+psychological+interventions+for+post-traumatic+stress+disorder+in+children%2C+adolescents+and+young+adults%3A+a+systematic+review+and+meta-analysis.&amp;aulast=John-Baptiste+Bastien&amp;pid=%3Cauthor%3EJohn-Baptiste+Bastien+R%3C%2Fauthor%3E%3CAN%3E32624017%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.cambridge.org/core/journals/psychological-medicine/article/effectiveness-of-psychological-interventions-for-posttraumatic-stress-disorder-in-children-adolescents-and-young-adults-a-systematic-review-and-metaanalysis/0E128C06770F09578E8E0BC13813CE88
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0E128C06770F09578E8E0BC13813CE88/S0033291720002007a.pdf/div-class-title-the-effectiveness-of-psychological-interventions-for-post-traumatic-stress-disorder-in-children-adolescents-and-young-adults-a-systematic-review-and-meta-analysis-div.pdf
ER  -
TY  - JOUR
AB  - LAY ABSTRACT: Difficulty with communication and social functioning are two outstanding core symptoms of autism spectrum disorder, while there is no efficacious pharmacologic treatment available to deal with them. Traditional behavioral therapies usually require specialist therapist and be conducted in specific settings, increasing burdens on families and individuals with autism. Physical activity has long been found to promote physical and mental well-beings, and it is more affordable and versatile than traditional therapies. There is preliminary support for the use of physical activity interventions to improve communication and social functioning in individuals with autism. In this study, we quantitatively aggregate data from existing controlled trials to provide an up-to-date inquiry into the effectiveness of physical activity interventions on communication and social functioning in autistic children and adolescents. We included 12 trials involving 350 participants (8 trials reported communication outcomes and 11 trials reported social functioning outcomes) and found small to moderate benefits on communication and social functioning. Further analyses showed that the benefit of physical activity interventions is greater in younger participants. Results of this study suggest that physical activity interventions are effective to improve communication and social functioning in autistic children and adolescents, and early participation in the interventions can be more beneficial. Given their affordability, versatility, and efficacy, physical activity interventions could be considered a cost-effective option for autism spectrum disorder management in the future.
AD  - Chan, John Sy. China Institute of Sport Science, P.R. China.Deng, Kanfeng. China Institute of Sport Science, P.R. China.Yan, Jin H. China Institute of Sport Science, P.R. China.
AN  - 33307759
AU  - Chan,
AU  - J.
AU  - S.
AU  - Deng,
AU  - K.
AU  - Yan,
AU  - J.
AU  - H.
DA  - Dec 11
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1362361320977645
DP  - Ovid Technologies
J2  - Autism
L1  - internal-pdf://1254616141/Chan-2020.pdf
LA  - English
N1  - Chan, John SyDeng, KanfengYan, Jin H
PY  - 2020
SP  - 1362361320977645
T2  - Autism
TI  - The effectiveness of physical activity interventions on communication and social functioning in autistic children and adolescents: A meta-analysis of controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33307759
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33307759&amp;id=doi:10.1177%2F1362361320977645&amp;issn=1362-3613&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1362361320977645&amp;pages=1362361320977645&amp;date=2020&amp;title=Autism&amp;atitle=The+effectiveness+of+physical+activity+interventions+on+communication+and+social+functioning+in+autistic+children+and+adolescents%3A+A+meta-analysis+of+controlled+trials.&amp;aulast=Chan&amp;pid=%3Cauthor%3EChan+JS%3C%2Fauthor%3E%3CAN%3E33307759%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/10.1177/1362361320977645
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1362361320977645
ER  -
TY  - JOUR
AB  - In this study, we looked at published research on interventions for young autistic children that did not involve administering medication. We were interested in determining how often studies reported on whether adverse events (i.e. physical or psychological distress to the participants) or adverse effects (i.e. adverse events that are thought to be caused by the intervention) had occurred. We found that of the 150 reports we examined, only 11 mentioned adverse events. One of these studies reported adverse events occurred, and three reported that adverse effects occurred. We also reviewed the studies to examine the reasons that were given to explain why any participants dropped out of the intervention (termed &quot;withdrawal&quot;), to determine if any of these reasons could be considered adverse events or adverse effects. Fifty-four studies described reasons for withdrawal, and 10 of these studies had reasons that could be categorized as an adverse event, 8 studies had reasons that could be categorized as an adverse effect, and an additional 12 studies had reasons that were too vaguely described to determine whether they were adverse events or not. We recommend that autism intervention researchers develop more systematic methods of looking for and reporting adverse events and effects, so that professionals and families can be better informed when choosing to enroll their autistic children in interventions.
AD  - Bottema-Beutel, Kristen. Boston College, USA.Crowley, Shannon. Boston College, USA.Sandbank, Micheal. University of Texas at Austin, USA.Woynaroski, Tiffany G. Vanderbilt University Medical Center, USA.
AN  - 33076682
AU  - Bottema-Beutel,
AU  - K.
AU  - Crowley,
AU  - S.
AU  - Sandbank,
AU  - M.
AU  - Woynaroski,
AU  - T.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1362361320965331
DP  - Ovid Technologies
J2  - Autism
L1  - internal-pdf://0189217354/Bottema-Beutel-2020.pdf
LA  - English
N1  - Bottema-Beutel, KristenCrowley, ShannonSandbank, MichealWoynaroski, Tiffany G
PY  - 2020
SP  - 1362361320965331
T2  - Autism
TI  - Adverse event reporting in intervention research for young autistic children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33076682
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33076682&amp;id=doi:10.1177%2F1362361320965331&amp;issn=1362-3613&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1362361320965331&amp;pages=1362361320965331&amp;date=2020&amp;title=Autism&amp;atitle=Adverse+event+reporting+in+intervention+research+for+young+autistic+children.&amp;aulast=Bottema-Beutel&amp;pid=%3Cauthor%3EBottema-Beutel+K%3C%2Fauthor%3E%3CAN%3E33076682%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/10.1177/1362361320965331
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1362361320965331
ER  -
TY  - JOUR
AB  - **Background:** 
Pediatric obesity impacts on multiple domains of psychological health, including self-esteem and body image. 

**Objective(s):** 
To determine the effect of multicomponent pediatric obesity treatment interventions on self-esteem and body image. 

**Method(s):**
A systematic search of published literature up to June 2019 was undertaken using electronic databases MEDLINE, EMBASE, Cochrane Library, and PsychINFO. Eligible studies implemented an obesity treatment intervention, including a dietary and physical activity component with/without a behavioral component, in children and adolescents with overweight/obesity, and assessed self-esteem and/or body image. Data were extracted by one reviewer and cross-checked. Meta-analysis was used to combine outcome data and moderator analysis conducted to identify intervention characteristics influencing outcomes. 

**Result(s):** 
64 studies were identified. Meta-analysis of 49 studies (n = 10471) indicated that pediatric obesity treatment results in increased self-esteem postintervention (standardized mean difference, [SE] 0.34 [0.03], P &lt;.001, I&lt;sup&gt;2&lt;/sup&gt; 87%), maintained at follow-up (0.35 [0.05] P &lt;.001, I&lt;sup&gt;2&lt;/sup&gt; 79%, 17 studies). Similarly, meta-analysis of 40 studies (n = 2729) indicated improvements in body image postintervention (0.40 [0.03], P &lt;.001, I&lt;sup&gt;2&lt;/sup&gt; 73%), maintained at follow-up (0.41 [0.08], P &lt;.001, I&lt;sup&gt;2&lt;/sup&gt; 89%, 16 studies). 

**Conclusion(s):** 
Pediatric obesity treatment improves self-esteem and body image in the short and medium term. These findings may underpin improvements in other psychological outcomes. Copyright &copy; 2020 World Obesity Federation
AD  - (Gow, Garnett, Baur, Lister, Jebeile) The University of Sydney, Children&#039;s Hospital Westmead Clinical School, Sydney, Australia (Gow, Garnett, Aldwell, Thomas, Lister, Jebeile) Institute of Endocrinology and Diabetes, The Children&#039;s Hospital at Westmead, Sydney, Australia (Tee) The University of Sydney, Faculty of Medicine and Health, Sydney, Australia (Baur) Weight Management Services, The Children&#039;s Hospital at Westmead, Sydney, Australia (Paxton) School of Psychology and Public Health, La Trobe University, Melbourne, AustraliaM.L. Gow, The University of Sydney, Children&#039;s Hospital Westmead Clinical School, Sydney, Australia. E-mail: megan.gow@health.nsw.gov.au
AN  - 2004197279
AU  - Gow,
AU  - M.
AU  - L.
AU  - Tee,
AU  - M.
AU  - S.
AU  - Y.
AU  - Garnett,
AU  - S.
AU  - P.
AU  - Baur,
AU  - L.
AU  - A.
AU  - Aldwell,
AU  - K.
AU  - Thomas,
AU  - S.
AU  - Lister,
AU  - N.
AU  - B.
AU  - Paxton,
AU  - S.
AU  - J.
AU  - Jebeile,
AU  - H.
DA  - 01 Mar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/ijpo.12600
DP  - Ovid Technologies
KW  - body image
KW  - obesity
KW  - obesity treatment
KW  - self-esteem
KW  - systematic review
KW  - behavior modification
KW  - body weight loss
KW  - childhood obesity/th [Therapy]
KW  - cognitive behavioral therapy
KW  - diet therapy
KW  - follow up
KW  - human
KW  - meta analysis
KW  - outcome assessment
KW  - physical activity
KW  - priority journal
KW  - randomized controlled trial (topic)
KW  - review
KW  - self esteem
L1  - internal-pdf://0754164746/Gow_et_al-2020-Pediatric_Obesity.pdf
LA  - English
M3  - Review
PY  - 2020
T2  - Pediatric Obesity
TI  - Pediatric obesity treatment, self-esteem, and body image: A systematic review with meta-analysis
UR  - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)2047-6310/issues
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2004197279
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:32020780&amp;id=doi:10.1111%2Fijpo.12600&amp;issn=2047-6302&amp;isbn=&amp;volume=15&amp;issue=3&amp;spage=e12600&amp;pages=&amp;date=2020&amp;title=Pediatric+Obesity&amp;atitle=Pediatric+obesity+treatment%2C+self-esteem%2C+and+body+image%3A+A+systematic+review+with+meta-analysis&amp;aulast=Gow&amp;pid=%3Cauthor%3EGow+M.L.%3C%2Fauthor%3E%3CAN%3E2004197279%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/ijpo.12600
VL  - 15 (3) (no pagination)
ER  -
TY  - JOUR
AB  - **Background**
Rates of anxiety and depression are increasing among children and young people. Recent policies have focused on primary prevention of mental disorders in children and young people, with schools at the forefront of implementation. There is limited information for the comparative effectiveness of the multiple interventions available.

**Methods**
We did a systematic review and network meta-analysis, searching MEDLINE, Embase, PsycINFO, and Cochrane Central Register of Controlled trials for published and unpublished, passive and active-controlled randomised and quasi-randomised trials. We included educational setting-based, universal, or targeted interventions in which the primary aim was the prevention of anxiety and depression in children and young people aged 4&ndash;18 years. Primary outcomes were post-intervention self-report anxiety and depression, wellbeing, suicidal ideation, or self-harm. We assessed risk of bias following the Cochrane Handbook for Systematic Reviews of Interventions. We estimated standardised mean differences (SMD) using random effects network meta-analysis in a Bayesian framework. The study is registered with PROPSERO, number CRD42016048184.

**Findings**
1512 full-text articles were independently screened for inclusion by two reviewers, from which 137 studies of 56 620 participants were included. 20 studies were assessed as being at low risk of bias for both random sequence generation and allocation concealment. There was weak evidence to suggest that cognitive behavioural interventions might reduce anxiety in primary and secondary settings. In universal secondary settings, mindfulness and relaxation-based interventions showed a reduction in anxiety symptoms relative to usual curriculum (SMD &minus;0&middot;65, 95% credible interval &minus;1&middot;14 to &minus;0&middot;19). There was a lack of evidence to support any one type of intervention being effective to prevent depression in universal or targeted primary or secondary settings. Comparison-adjusted funnel plots suggest the presence of small-study effects for the universal secondary anxiety analysis. Network meta-analysis was not feasible for wellbeing or suicidal ideation or self-harm outcomes, and results are reported narratively.

**Interpretation**
Considering unclear risk of bias and probable small study effects for anxiety, we conclude there is little evidence that educational setting-based interventions focused solely on the prevention of depression or anxiety are effective. Future research could consider multilevel, systems-based interventions as an alternative to the downstream interventions considered here.

**Funding**
UK National Institute for Health Research.
AN  - WOS:000564105900001
AU  - Caldwell,
AU  - D.
AU  - M.
AU  - Davies,
AU  - S.
AU  - R.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Palmer,
AU  - J.
AU  - C.
AU  - Caro,
AU  - P.
AU  - Lopez-Lopez,
AU  - J.
AU  - A.
AU  - Gunnell,
AU  - D.
AU  - Kidger,
AU  - J.
AU  - Thomas,
AU  - J.
AU  - French,
AU  - C.
AU  - Stockings,
AU  - E.
AU  - Campbell,
AU  - R.
AU  - Welton,
AU  - N.
AU  - J.
DA  - https://doi.org/10.1016/S2215-0366(19)30403-1
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - Tom verdi
L1  - internal-pdf://2845721583/Caldwell-2020.pdf
N1  - Caldwell, Deborah M. Davies, Sarah R. Hetrick, Sarah E. Palmer, Jennifer C. Caro, Paola Lopez-Lopez, Jose A. Gunnell, David Kidger, Judi Thomas, James French, Clare Stockings, Emily Campbell, Rona Welton, Nicky J.Gunnell, David/ABE-6653-2020Gunnell, David/0000-0002-0829-6470
PY  - 2020
SP  - E59-E59
T2  - Lancet Psychiatry
TI  - School-based interventions to prevent anxiety and depression in children and young people: a systematic review and network meta-analysis (vol 6, pg 1011, 2019)
UR  - &lt;Go to ISI&gt;://WOS:000564105900001
VL  - 7
ER  -
TY  - JOUR
AB  - **Purpose** 
This study synthesized effects of interventions on language outcomes of young children (ages 0-8 years) with autism and evaluated the extent to which summary effects varied by intervention, participant, and outcome characteristics. 

**Method** 
A subset of effect sizes gathered for a larger meta-analysis (the Autism Intervention Meta-analysis or Project AIM) examining the effects of interventions for young children with autism, which were specific to language outcomes, was analyzed. Robust variance estimation and metaregression were used to calculate summary and moderated effects while controlling for intercorrelation among outcomes within studies. 

**Results** 
A total of 221 outcomes were gathered from 60 studies. The summary effect of intervention on language outcomes was small but significant. Summary effects were larger for expressive and composite language outcomes compared to receptive language outcomes. Interventions implemented by clinicians, or by clinicians and caregivers together, had summary effects that were significantly larger than interventions implemented by caregivers alone. Participants &#039; pretreatment language age equivalent scores positively and significantly moderated intervention effects, such that effects were significantly larger on average when samples of children had higher pretreatment language levels. Effects were not moderated by cumulative intervention intensity, intervention type, autism symptomatology, chronological age, or the proximity or boundedness of outcomes. Study quality concerns were apparent for a majority of included outcomes. 

**Conclusions** 
We found evidence that intervention can facilitate improvements in language outcomes for young children with autism. Effects were largest for expressive and composite language outcomes, for children with initially higher language abilities, and for interventions implemented by clinicians or by caregivers and clinicians combined. However, quality concerns of included studies and borderline significance of some results temper our conclusions regarding intervention effectiveness and corresponding moderators.
AD  - Sandbank, Micheal. Special Education Department, The University of Texas at Austin.Bottema-Beutel, Kristen. Lynch School of Education and Human Development, Boston College, MA.Crowley, Shannon. Lynch School of Education and Human Development, Boston College, MA.Cassidy, Margaret. College of Arts and Sciences, Vanderbilt University, Nashville, TN.Feldman, Jacob I. Department of Hearing and Speech Sciences, Vanderbilt University, Nashville, TN.Canihuante, Marcos. Special Education Department, The University of Texas at Austin.Woynaroski, Tiffany. Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Vanderbilt Kennedy Center, Vanderbilt Brain Institute, Nashville, TN.
AN  - 32384865
AU  - Sandbank,
AU  - M.
AU  - Bottema-Beutel,
AU  - K.
AU  - Crowley,
AU  - S.
AU  - Cassidy,
AU  - M.
AU  - Feldman,
AU  - J.
AU  - I.
AU  - Canihuante,
AU  - M.
AU  - Woynaroski,
AU  - T.
DA  - May 22
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1044/2020_JSLHR-19-00167
DP  - Ovid Technologies
J2  - J Speech Lang Hear Res
L1  - internal-pdf://1731165180/Sandbank-2020.pdf
LA  - English
N1  - Sandbank, MichealBottema-Beutel, KristenCrowley, ShannonCassidy, MargaretFeldman, Jacob ICanihuante, MarcosWoynaroski, Tiffany
PY  - 2020
SP  - 1537-1560
T2  - Journal of Speech Language &amp; Hearing Research
TI  - Intervention Effects on Language in Children With Autism: A Project AIM Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32384865
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32384865&amp;id=doi:10.1044%2F2020_JSLHR-19-00167&amp;issn=1092-4388&amp;isbn=&amp;volume=63&amp;issue=5&amp;spage=1537&amp;pages=1537-1560&amp;date=2020&amp;title=Journal+of+Speech+Language+%26+Hearing+Research&amp;atitle=Intervention+Effects+on+Language+in+Children+With+Autism%3A+A+Project+AIM+Meta-Analysis.&amp;aulast=Sandbank&amp;pid=%3Cauthor%3ESandbank+M%3C%2Fauthor%3E%3CAN%3E32384865%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 63
ER  -
TY  - JOUR
AB  - **Introduction: **
Vitamin D plays an important role in brain development in experimental studies; however, the effect of vitamin D deficiency on child development remains inadequately characterized. We aimed to estimate the effects of vitamin D deficiency on neurobehavioural outcomes in children up to 18 years of age.

**Methods:**
We searched PubMed, EMBASE, PsycINFO, Scopus, Cochrane Library, Web of Science and Open Grey for published studies up to 10th January 2020. We included all studies that assessed the effects of maternal or child vitamin D status or vitamin D supplementation on neurobehavioural outcomes in children. Study findings were synthesized qualitatively as the high level of heterogeneity in study populations and methodologies precluded a quantitative meta-analysis.

**Results: **
Our search identified 5,633 studies, of which 32 studies with 31,445 participants from 18 countries were included in the systematic review. Of the studies identified, two were randomized controlled trials (RCTs) of vitamin D supplementation in children, while 30 were observational. One RCT (n=55) reported a beneficial effect of supplementation with lower doses compared to higher doses of vitamin D on motor development while the other RCT (n=70) found no beneficial effect of vitamin D supplementation on cognition in extremely preterm infants. Twelve mother-child studies (n=17,136) and five studies in children (n=1,091) reported an association between low maternal or child 25-hydroxyvitamin D levels and impaired neurobehavioural outcomes in children, while 15 mother-child studies (n=20,778) and eight studies in children (n=7,496) reported no association.

**Conclusions: **
Although animal studies point to an effect of vitamin D deficiency on brain development, there are few studies on the effects of vitamin D deficiency on neurobehavioural outcomes in children and their findings are inconsistent. There is a need for well-conducted, adequately powered studies to further determine these effects in children.
AN  - 32399499
AU  - Mutua,
AU  - A.
AU  - M.
AU  - Mogire,
AU  - R.
AU  - M.
AU  - Elliott,
AU  - A.
AU  - M.
AU  - Williams,
AU  - T.
AU  - N.
AU  - Webb,
AU  - E.
AU  - L.
AU  - Abubakar,
AU  - A.
AU  - Atkinson,
AU  - S.
AU  - H.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.12688/wellcomeopenres.15730.1
L1  - internal-pdf://2367892301/Mutua-2020-Effects of vitamin D deficiency on.pdf
PY  - 2020
SP  - 28
T2  - Wellcome Open Research
TI  - Effects of vitamin D deficiency on neurobehavioural outcomes in children: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medv&amp;AN=32399499
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7194460/pdf/wellcomeopenres-5-17601.pdf
VL  - 5
ER  -
TY  - JOUR
AB  - **Objective:** 
Reviews on child outcomes following in utero antidepressant exposure have focused on short-term outcomes. However, several recent individual studies reported on adverse physical, neurodevelopmental, and psychiatric outcomes beyond infancy and early childhood. The objective of this systematic review was to establish the long-term effects of prenatal antidepressant exposure on physical, neurodevelopmental, and psychiatric outcomes in individuals aged 4 years and older. 

**Data Sources:** 
Embase, MEDLINE Ovid, Web of Science, Cochrane Central, and Google Scholar were systematically searched for all relevant articles, written in English and published prior to November 8, 2018, using terms describing antidepressants, pregnancy, and developmental outcomes. 

**Study Selection:** 
All original research articles on long-term outcomes of prenatal antidepressant exposure were eligible for inclusion. After screening and removal of duplicates, a total of 34 studies were identified. 

**Data Extraction:** 
Included articles were qualitatively analyzed to determine inconsistency, indirectness, imprecision, and study bias. 

**Result(s):** 
The identified studies demonstrated statistically significant associations between prenatal antidepressant exposure and a range of physical, neurodevelopmental, and psychiatric outcomes. Yet, the risk of confounding by indication was high. When controlling for confounders, 5 studies investigating physical outcomes (asthma, cancer, body mass index [BMI], epilepsy) found no association except conflicting outcomes for BMI. Eighteen studies examining neurodevelopmental outcomes (cognition, behavior, IQ, motor development, speech, language, and scholastic outcomes) found no consistent associations with antidepressant exposure after taking confounders into account. Eleven studies investigated psychiatric outcomes. After adjusting for confounders, prenatal antidepressant exposure was associated with affective disorders but not with childhood psychiatric outcomes (eg, autism spectrum disorders, attention-deficit/hyperactivity disorder). 

**Conclusion(s):** 
Reported associations between in utero exposure to antidepressants and physical, neurodevelopmental, and psychiatric outcomes, in large part, seem to be driven by the underlying maternal disorder. When limiting confounding by indication, prenatal exposure to antidepressants was significantly associated only with offspring BMI and affective disorders. Copyright &copy; 2020 Physicians Postgraduate Press, Inc.
AD  - (Rommel, Bergink, Molenaar) Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY 10029, United States (Bergink) Department of Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, United States (Liu, Munk-Olsen) National Centre for Register-based Research, Aarhus University, Aarhus, Denmark (Munk-Olsen) Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark (Munk-Olsen) CIRRAU (Center for Integrated Register-based Research), Aarhus University, Aarhus, DenmarkA.-S. Rommel, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl, New York, NY 10029, United States. E-mail: anna.rommel@mssm.edu
AN  - 2006957300
AU  - Rommel,
AU  - A.
AU  - S.
AU  - Bergink,
AU  - V.
AU  - Liu,
AU  - X.
AU  - Munk-Olsen,
AU  - T.
AU  - Molenaar,
AU  - N.
AU  - M.
DA  - June
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.4088/JCP.19r12965
DP  - Ovid Technologies
KW  - asthma
KW  - attention deficit disorder
KW  - autism
KW  - body mass
KW  - child psychiatry
KW  - cognition
KW  - drug effect
KW  - epilepsy
KW  - human
KW  - intelligence quotient
KW  - language
KW  - long term care
KW  - malignant neoplasm
KW  - motor development
KW  - nerve cell differentiation
KW  - physical disease
KW  - prenatal drug exposure
KW  - priority journal
KW  - psychiatry
KW  - review
KW  - speech
KW  - systematic review
KW  - antidepressant agent
L1  - internal-pdf://1673157530/Rommel-2020.pdf
LA  - English
M3  - Review
PY  - 2020
T2  - Journal of Clinical Psychiatry
TI  - Long-term effects of intrauterine exposure to antidepressants on physical, neurodevelopmental, and psychiatric outcomes: A systematic review
UR  - https://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2020/v81/19r12965.aspx&amp;Type=Article
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2006957300
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:32412703&amp;id=doi:10.4088%2FJCP.19r12965&amp;issn=0160-6689&amp;isbn=&amp;volume=81&amp;issue=3&amp;spage=19r12965&amp;pages=&amp;date=2020&amp;title=Journal+of+Clinical+Psychiatry&amp;atitle=Long-term+effects+of+intrauterine+exposure+to+antidepressants+on+physical%2C+neurodevelopmental%2C+and+psychiatric+outcomes%3A+A+systematic+review&amp;aulast=Rommel&amp;pid=%3Cauthor%3ERommel+A.-S.%3C%2Fauthor%3E%3CAN%3E2006957300%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.psychiatrist.com/JCP/article/Pages/2020/v81/19r12965.aspx
UR  - https://www.psychiatrist.com/JCP/article/Pages/long-term-effects-of-prenatal-antidepressant-exposure.aspx
VL  - 81 (3) (no pagination)
ER  -
TY  - JOUR
AB  - CONTEXT: Zinc is an essential trace mineral required for the function of brain and neural structures. The role of zinc supplementation in the prevention and treatment of depression has been suggested in clinical studies that reported a reduction in depressive symptoms.

OBJECTIVE: The aim of this review was to determine whether zinc supplementation vs placebo can prevent or improve depressive symptoms in children, adolescents, or adults.

DATA SOURCES: Five electronic databases were searched, and studies published until September 2019 were included without language restriction.

STUDY SELECTION: Randomized, controlled, crossover trials that evaluated the effect of zinc supplementation vs a comparator for prevention or improvement of depressive symptoms in children, adolescents, or adults were eligible for inclusion.

DATA EXTRACTION: Two authors independently performed data extraction and risk-of-bias assessment.

RESULTS: The initial search identified 12 322 studies, 5 of which were eligible for meta-analysis. The standardized mean difference (SMD) showed an average reduction of 0.36 point (95%CI, -0.67 to -0.04) in the intervention group compared with the placebo group. Forstudies in which the mean age of participants was &gt;= 40 years, the SMD was reduced by 0.61 point (95%CI, -1.12 to -0.09) in the intervention group vs the placebo group. The meta-analysis by sample size (&lt; 60 individuals and &gt;= 60 individuals) did not show an effect of zinc supplementation in reducing depressive symptoms (SMD -0.28; 95%CI, -0.67 to -0.10; and SMD -0.52; 95%CI, -1.10 to 0.06).

CONCLUSION: Zinc supplementation may reduce depressive symptoms in individuals treated with antidepressant drugs for clinical depression.

SYSTEMATIC REVIEW REGISTRATION: PROSPERO registration number CRD42018081691.
AD  - da Silva, Lais Eloy Machado. L.E.M. da Silva, E.M. Pereira, and C.M.M. Nepomuceno are with the Graduate Program in Food, Nutrition and Health, Federal University of Bahia, Salvador, Brazil.de Santana, Monica Leila Portela. M.L.P. de Santana, P.R.d.F. Costa, V.A.d.O. Queiroz, L.P.M. de Oliveira, and M.E.P. de Conceicao-Machado are with the Department of Nutrition Science, Federal University of Bahia, Salvador, Brazil.Costa, Priscila Ribas de Farias. M.L.P. de Santana, P.R.d.F. Costa, V.A.d.O. Queiroz, L.P.M. de Oliveira, and M.E.P. de Conceicao-Machado are with the Department of Nutrition Science, Federal University of Bahia, Salvador, Brazil.Pereira, Emile Miranda. L.E.M. da Silva, E.M. Pereira, and C.M.M. Nepomuceno are with the Graduate Program in Food, Nutrition and Health, Federal University of Bahia, Salvador, Brazil.Nepomuceno, Carina Marcia Magalhaes. L.E.M. da Silva, E.M. Pereira, and C.M.M. Nepomuceno are with the Graduate Program in Food, Nutrition and Health, Federal University of Bahia, Salvador, Brazil.Queiroz, Valterlinda Alves de Oliveira. M.L.P. de Santana, P.R.d.F. Costa, V.A.d.O. Queiroz, L.P.M. de Oliveira, and M.E.P. de Conceicao-Machado are with the Department of Nutrition Science, Federal University of Bahia, Salvador, Brazil.de Oliveira, Lucivalda Pereira Magalhaes. M.L.P. de Santana, P.R.d.F. Costa, V.A.d.O. Queiroz, L.P.M. de Oliveira, and M.E.P. de Conceicao-Machado are with the Department of Nutrition Science, Federal University of Bahia, Salvador, Brazil.Machado, Maria Ester Pereira da Conceicao-. M.L.P. de Santana, P.R.d.F. Costa, V.A.d.O. Queiroz, L.P.M. de Oliveira, and M.E.P. de Conceicao-Machado are with the Department of Nutrition Science, Federal University of Bahia, Salvador, Brazil.de Sena, Eduardo Ponde. E.P. de Sena is with the Department of Pharmacology, Institute of Health Sciences, Federal University of Bahia, Salvador, Brazil.
AN  - 32885249
AU  - da
AU  - Silva,
AU  - L.
AU  - E.
AU  - M.
AU  - de
AU  - Santana,
AU  - M.
AU  - L.
AU  - P.
AU  - Costa,
AU  - P.
AU  - R.
AU  - F.
AU  - Pereira,
AU  - E.
AU  - M.
AU  - Nepomuceno,
AU  - C.
AU  - M.
AU  - M.
AU  - Queiroz,
AU  - V.
AU  - A.
AU  - O.
AU  - de
AU  - Oliveira,
AU  - L.
AU  - P.
AU  - M.
AU  - Machado,
AU  - Mepdc
AU  - de
AU  - Sena,
AU  - E.
AU  - P.
DA  - Sep 04
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/nutrit/nuaa039
DP  - Ovid Technologies
J2  - Nutr Rev
L1  - internal-pdf://2695828873/da Silva-2020.pdf
LA  - English
N1  - Using Smart Source ParsingSepda Silva, Lais Eloy Machadode Santana, Monica Leila PortelaCosta, Priscila Ribas de FariasPereira, Emile MirandaNepomuceno, Carina Marcia MagalhaesQueiroz, Valterlinda Alves de Oliveirade Oliveira, Lucivalda Pereira MagalhaesMachado, Maria Ester Pereira da Conceicao-de Sena, Eduardo Pondenuaa039
PY  - 2020
SP  - 04
T2  - Nutrition Reviews
TI  - Zinc supplementation combined with antidepressant drugs for treatment of patients with depression: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32885249
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32885249&amp;id=doi:10.1093%2Fnutrit%2Fnuaa039&amp;issn=0029-6643&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Nutrition+Reviews&amp;atitle=Zinc+supplementation+combined+with+antidepressant+drugs+for+treatment+of+patients+with+depression%3A+a+systematic+review+and+meta-analysis.&amp;aulast=da+Silva&amp;pid=%3Cauthor%3Eda+Silva+LEM%3C%2Fauthor%3E%3CAN%3E32885249%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://academic.oup.com/nutritionreviews/advance-article-abstract/doi/10.1093/nutrit/nuaa039/5901339?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/nuaa039.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAuUwggLhBgkqhkiG9w0BBwagggLSMIICzgIBADCCAscGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMJMPC92qDCk5ORRtVAgEQgIICmEXS-KplBXHBuXaCzeiKJM82DPOgi7Z91S6aRnvkDznN5gKoK8lK7ZQVgBU6d_GEbIn9NXdy5bW_czxW_cDaeokt3w5xAOD1RTeY15wBQAq9SjQqzoCmEgBlmwyCDjDmlB-uC27BawgMFLzOLPQdNp17WJfFNSQbitBTZv9p-2-irt4qraMsevdP61a617ZO2xGmirvyoIfg3C4sx9TDbAS-jLb7s6mQAbCwjrM9yv_Arb014WtoOJgwhFhKevnbGCJiD4lBVQOpurWi3LgRaQ8nKeIhdhXkmEJ2L2k2nYzmNoYDKgBur0O6lZAR5O5M2zprT1EV1iKKSF2WllcJJNY3FesLLkXMVOIuHahqG3SgsjSG390CL7H06l3WHadvFB5185usQ4UzdH96pBszoNfcU9BPr99a4uRmf8Pab7cd86ezVaSeuVh8U97-iD3gl_O0mx_5j97NLAd2I5nrUAhl8li2cjlD9Ooa6xnCyagdX5GoeX0yhYr56mhksoPbew9nXCSKq1ZR0bEgyGg8XyLEZIKaMUuPSMjobE7E7bfVRAzZwgxGVhJbhV4zAWxwkVL3C1lgZip6ecZBIADl7znU6GFh2f2f9FjYs-qw8f0y0QkL6sdlak3OHGbbmPpmFZJbqbWtnb8FGim4YjDOgXUKvXz_XvCDbYUKHj6o6T3UfBBsE0hATqmkHG2Fz_dIGef854UpJ3L2sw54QRweipfl_soEa7Vkn3esaGIn3wHwfUIP3Yzjnrq4Ja0MBscO9CATkbHjF-od6YSYwK__RT-AxRKfFPZmNhFRt2sIjUNE_061rxO2A5mz6OG2Cew7NGF1XirL4S1a4kvWmzFpIW9UDYJai8J0ZLmH6WEbBhWLriFixqPHXas
VL  - 04
ER  -
TY  - JOUR
AB  - **Background:** 
International comparisons found that depression prevalence ranged from 18.3% (China) to 51.5% (Zambia) among school students in some low- and middle-income countries (LMICs). The evidence base for treatment of adolescent depression in LMICs is limited and inadequate. Moreover, most treatment interventions are developed in high income countries and the effectiveness of these treatments in LMICs is largely unknown. 

**Method(s):** 
Randomized controlled trials, including cluster-randomized trials that have been implemented in LMICs to reduce adolescent depression, were examined in this systematic review and meta-analysis. Only one-time point (3 months or close to 3 months) of the outcome measures was chosen to evaluate effectiveness of interventions. 

**Result(s):** 
Studies that used cognitive-behavioral therapy reduced depressive symptoms more effectively than other treatments with standardized mean difference (SMD) = -1.27, (95% CI -2.19 to -0.35). Microfinance/economic interventions also reduced depression in adolescents with SMD = - 0.35, (95% CI -0.71 to 0.01) and Interpersonal therapy was used in three studies and depressive symptoms reduced by SMD = -0.23, (95% IC -0.60 to 0.13). Moreover, complex psychotherapeutic interventions that used integrated techniques showed a reduction in depression with SMD = -0.23, (95% IC -0.33 to -0.14) as well. 

**Conclusion(s):** 
Across twenty-eight studies, the evidence showed that cognitive behavioral therapy that delivered by nurses, social workers and counselors at community-based settings were more effective treatments in decreasing adolescent depression in LMICs. Future studies should implement these universal treatment approaches to identify accessible, feasible, affordable and sustainable depression treatments in the countries with less available resources. Copyright &copy; 2020 Elsevier Ltd
AD  - (Hauwadhanasuk) School of Education, Saint Louis University, St. Louis, MO 63103, United States (Matsuo) Department of Sociology and Anthropology, Saint Louis University, St. Louis, MO 63103, United States (Szatmari) Center for Addiction and Mental Health, Canada and University of Toronto, Canada (Davaasambuu) Research Foundation of CUNY, 230 W 41 Street, New York, NY 10035, United StatesS. Davaasambuu, Research Foundation of CUNY, 230 W 41 Street, New York, NY 10035, United States. E-mail: dsaraa@gmail.com
AN  - 2004975197
AU  - Davaasambuu,
AU  - S.
AU  - Hauwadhanasuk,
AU  - T.
AU  - Matsuo,
AU  - H.
AU  - Szatmari,
AU  - P.
DA  - April
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jpsychires.2020.01.020
DP  - Ovid Technologies
KW  - adolescent depression
KW  - cognitive behavioral therapy
KW  - comparative effectiveness
KW  - controlled study
KW  - counselor
KW  - human
KW  - meta analysis
KW  - middle income country
KW  - nurse
KW  - outcome assessment
KW  - randomized controlled trial (topic)
KW  - review
KW  - social worker
KW  - systematic review
L1  - internal-pdf://2053706294/Davaasambuu-2020-Effects of interventions to r.pdf
LA  - English
M3  - Review
PY  - 2020
SP  - 201-215
T2  - Journal of Psychiatric Research
TI  - Effects of interventions to reduce adolescent depression in low- and middle-income countries: A systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/jpsychires
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2004975197
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jpsychires.2020.01.020&amp;issn=0022-3956&amp;isbn=&amp;volume=123&amp;issue=1&amp;spage=201&amp;pages=201-215&amp;date=2020&amp;title=Journal+of+Psychiatric+Research&amp;atitle=Effects+of+interventions+to+reduce+adolescent+depression+in+low-+and+middle-income+countries%3A+A+systematic+review+and+meta-analysis&amp;aulast=Davaasambuu&amp;pid=%3Cauthor%3EDavaasambuu+S.%3C%2Fauthor%3E%3CAN%3E2004975197%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/271251/1-s2.0-S0022395620X00021/1-s2.0-S0022395619312312/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEFwaCXVzLWVhc3QtMSJHMEUCIQDCVDkAC8fFo7fpu9bgJIcLFrtNNSl%2FOWpkESjgCVPj9AIgbNWV0d16J56jcr8NnsgdWiefn6PxvDePHsQcEKGzDO8qtAMIdRADGgwwNTkwMDM1NDY4NjUiDMh5SbBBY%2FHwaLJT1iqRA03PdtQY29xHbgqpxOr2uMuz3ou1bQ%2FDZ0geRPbUHaxCMoW3QiuUq1RtPs39HY9mgtNDnGiKVLTX5jZZDL38jcshxY3gFwE44vVceE56M7A1lLdbPRKZMZHFqelY66WLJq5FcneQ95EVsj3powqeDQsPQ6zcjzoW60OmOO1fMQd3ZPg%2B%2Bsc%2F2ThCO8RwkBPSrUQj7wYkwaYn9s9KfRICxEVrKEvdNHwTTO9tU26vgP6dcXPQsKccDxFYCU1k%2BxMRhilWi8IxAJ2lyjlBm5uKsrW%2BzGvQyZd7YsYP%2F1ojdWyXmywmtaGggZOpfNr5jUQXetVS%2FcdAMor4j7XHBgZQbjk7y09l%2Bqcsq8radT050w7JLc9Mp9cvBF%2FO72WJlrVzqda%2BCQsJR54IWJrQL6OcPaIGULhZ6hemS78GW7ZGUPGIlZ9ZuGItFFfJqVUFI%2FH58yv5cYQLF%2FPlFYi6eBvoJUuQdpF%2Bj%2Bx%2FJYZH1hEpwc%2BQKZMsvWZpHAB0BKLrNo6%2FtePZxsswesGLPl%2BLdUjAAHftMJm71vQFOusBl5ARKN2EsEaK60l6cprAwYqSG9dHcKY0tMKYvf8JaeFuOdMPlLI3rW0I6SDDjNhe01SCOaT0eq3yIkU4SASvhA91iyKmmkx4fyemJvui68tgRmx0c%2FKrsWjQZAJcQ7Ujqo%2B0Mz0wm0KHjK0V9qgC%2BjHEqh4K8eQrFitEcGoBa4Onz4BlhBw7oKTNSU7uI2c4BzXA1wZFPpGCkw2M0no0BreNAtMKNkQwmw6N7%2FB%2BsyFzFr1G5Is4tdSj4NM3F%2FkkR6weMuuVzY%2Bkqn7%2FL6gMSBHc3hyaFrcwCr94nGKo8gZBb5gnPjNWdQ32DQ%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200414T121504Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYW3F3SY6Y%2F20200414%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=e9eef1a06c8670904ebdee960494edbce5cc7aff2be4199415db30ef63eac8a0&amp;hash=60435ecf07bac0dba1dc4f9cd8c14e9b381ad5143710f29fe9691dc7ead1d5d5&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0022395619312312&amp;tid=spdf-3b10dbec-e28f-447a-b6c0-29f10e1ee028&amp;sid=abe8b8954c72784b050ad27560a5b0b927a3gxrqb&amp;type=client
VL  - 123
ER  -
TY  - JOUR
AB  - BACKGROUND: The clinical high-risk state for psychosis (CHR-P) paradigm has facilitated the implementation of psychosis prevention into clinical practice; however, advancements in adolescent CHR-P populations are less established.

METHODS: We performed a PRISMA/MOOSE-compliant systematic review of the Web of Science database, from inception until 7 October 2019, to identify original studies conducted in CHR-P children and adolescents (mean age &lt;18 years). Findings were systematically appraised around core themes: detection, prognosis and intervention. We performed meta-analyses (employing Q statistics and I&lt;sup&gt;2&lt;/sup&gt; test) regarding the proportion of CHR-P subgroups, the prevalence of baseline comorbid mental disorders, the risk of psychosis onset and the type of interventions received at baseline. Quality assessment and publication bias were also analysed.

RESULTS: Eighty-seven articles were included (n = 4,667 CHR-P individuals). Quality of studies ranged from 3.5 to 8 (median 5.5) on a modified Newcastle-Ottawa scale. Detection: Individuals were aged 15.6 +/- 1.2 years (51.5% males), mostly (83%) presenting with attenuated positive psychotic symptoms. CHR-P psychometric accuracy improved when caregivers served as additional informants. Comorbid mood (46.4%) and anxiety (31.4%) disorders were highly prevalent. Functioning and cognition were impaired. Neurobiological studies were inconclusive.

PROGNOSIS: Risk for psychosis was 10.4% (95%CI: 5.8%-18.1%) at 6 months, 20% (95%CI: 15%-26%) at 12 months, 23% (95%CI: 18%-29%) at 24 months and 23.3% (95%CI: 17.3%-30.7%) at &gt;=36 months.

INTERVENTIONS: There was not enough evidence to recommend one specific treatment (including cognitive behavioural therapy) over the others (including control conditions) to prevent the transition to psychosis in this population. Randomised controlled trials suggested that family interventions, cognitive remediation and fish oil supplementation may improve cognition, symptoms and functioning. At baseline, 30% of CHR-P adolescents were prescribed antipsychotics and 60% received psychotherapy.

CONCLUSIONS: It is possible to detect and formulate a group-level prognosis in adolescents at risk for psychosis. Future interventional research is required.
AD  - Catalan, Ana. Mental Health Department - Biocruces Bizkaia Health Research Institute, Basurto University Hospital, Faculty of Medicine and Dentistry, University of the Basque Country - UPV/EHU, Biscay, Spain.Catalan, Ana. Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Salazar de Pablo, Gonzalo. Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Salazar de Pablo, Gonzalo. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon School of Medicine, IiSGM, CIBERSAM, Complutense University of Madrid, Madrid, Spain.Vaquerizo Serrano, Julio. Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Vaquerizo Serrano, Julio. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon School of Medicine, IiSGM, CIBERSAM, Complutense University of Madrid, Madrid, Spain.Mosillo, Pierluca. Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Mosillo, Pierluca. Faculty of Medicine and Surgery, University of Pavia, Pavia, Italy.Baldwin, Helen. Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Fernandez-Rivas, Aranzazu. Mental Health Department - Biocruces Bizkaia Health Research Institute, Basurto University Hospital, Faculty of Medicine and Dentistry, University of the Basque Country - UPV/EHU, Biscay, Spain.Moreno, Carmen. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon School of Medicine, IiSGM, CIBERSAM, Complutense University of Madrid, Madrid, Spain.Arango, Celso. Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon School of Medicine, IiSGM, CIBERSAM, Complutense University of Madrid, Madrid, Spain.Correll, Christoph U. The Zucker Hillside Hospital, Department of Psychiatry, Northwell Health, Glen Oaks, NY, USA.Correll, Christoph U. Department of Psychiatry and Molecular Medicine, Zucker School of Medicine at Hofstra/ Northwell, Hempstead, NY, USA.Correll, Christoph U. Center for Psychiatric Neuroscience, The Feinstein Institutes for Medical Research, Manhasset, NY, USA.Correll, Christoph U. Department of Child and Adolescent Psychiatry, Charite Universitatsmedizin, Berlin, Germany.Bonoldi, Ilaria. Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Fusar-Poli, Paolo. Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK.Fusar-Poli, Paolo. OASIS service, South London and Maudsley NHS Foundation Trust, London, UK.Fusar-Poli, Paolo. Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.Fusar-Poli, Paolo. National Institute for Health Research, Maudsley Biomedical Research Centre, South London and Maudsley NHS Foundation Trust, London, UK.
AN  - 32924144
AU  - Catalan,
AU  - A.
AU  - Salazar
AU  - de
AU  - Pablo,
AU  - G.
AU  - Vaquerizo
AU  - Serrano,
AU  - J.
AU  - Mosillo,
AU  - P.
AU  - Baldwin,
AU  - H.
AU  - Fernandez-Rivas,
AU  - A.
AU  - Moreno,
AU  - C.
AU  - Arango,
AU  - C.
AU  - Correll,
AU  - C.
AU  - U.
AU  - Bonoldi,
AU  - I.
AU  - Fusar-Poli,
AU  - P.
DA  - Sep 14
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13322
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
L1  - internal-pdf://3349024841/Catalan-2020-Annual Research Review_ Preventio.pdf
LA  - English
N1  - Using Smart Source ParsingSepCatalan, AnaSalazar de Pablo, GonzaloVaquerizo Serrano, JulioMosillo, PierlucaBaldwin, HelenFernandez-Rivas, AranzazuMoreno, CarmenArango, CelsoCorrell, Christoph UBonoldi, IlariaFusar-Poli, Paolo
PY  - 2020
SP  - 14
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Annual Research Review: Prevention of psychosis in adolescents - systematic review and meta-analysis of advances in detection, prognosis and intervention
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32924144
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32924144&amp;id=doi:10.1111%2Fjcpp.13322&amp;issn=0021-9630&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Annual+Research+Review%3A+Prevention+of+psychosis+in+adolescents+-+systematic+review+and+meta-analysis+of+advances+in+detection%2C+prognosis+and+intervention.&amp;aulast=Catalan&amp;pid=%3Cauthor%3ECatalan+A%3C%2Fauthor%3E%3CAN%3E32924144%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.13322?download=true
VL  - 14
ER  -
TY  - JOUR
AB  - **Objectives:** 
The aim of this study is to investigate the effectiveness of ACT on depression reduction and further examine the relationship between different follow-up periods, different degree of depression, and different age of patients through subgroup analysis. 

**Methods:** 
Relevant electronic databases were searched from Jan 2010 to Aug 2018, including CNKI, WANFANG, PubMed, EMBASE, Cochrane Library, PsycINFO. Two reviewers independently screened for eligible studies, extracted data, and assessed risk of bias of the included studies. The Cochrane Collaboration&#039;s bias assessment tool was used to evaluate the risk of bias for included studies, and Review Manager 5.3 Software for the meta-analysis.

**Results:**
18 studies with 1,088 participants were included in the review. Four studies were rated as high-quality studies, and the remaining 14 studies were rated as moderate quality studies. ACT significantly reduced depression as compared with the control group [SMD = 0.59, 95% CI (0.38, 0.81)]. The subgroup analysis found a significant difference between ACT and control group after post-intervention, three months follow up, mild depression group and adults group, [SMD= 0.62, 95% CI (0.35, 0.90), [SMD= 0.55, 95% CI (0.23, 0.87)], [SMD= 0.65, 95% CI (0.40, 0.91)], [SMD= 0.52, 95% CI (0.33, 0.71)] respectively. 

**Limitations:** 
The heterogeneity between included studies results in heterogeneity of the results. Most of the specific methods for random sequence generation and allocation concealment were not clear. The search results had limitations since only the published studies in Chinese and English were searched and lacked a search for gray and paper documents. 

**Conclusions:** 
The current study suggested that ACT was significantly for reducing depressive symptoms compared with the control group, especially at three months of follow-up, adult group and mild depression. More research is needed to investigate the difference effects for minor group, moderate and severe depression and long-term follow-up. (PsycINFO Database Record (c) 2019 APA, all rights reserved)
AD  - Bai, Zhenggang: 363212810@qq.comBai, Zhenggang: Evidence-Based Research Center of Social Science &amp; Health, Public Affair School, Nanjing University of Science &amp; Technology, Nanjing, China, 210000, 363212810@qq.comBai, Zhenggang: Evidence-Based Research Center of Social Science &amp; Health, Public Affair School, Nanjing University of Science &amp; Technology, Nanjing, ChinaLuo, Shiga: Evidence-Based Research Center of Social Science &amp; Health, Public Affair School, Nanjing University of Science &amp; Technology, Nanjing, ChinaZhang, Luyao: Evidence-Based Research Center of Social Science &amp; Health, Public Affair School, Nanjing University of Science &amp; Technology, Nanjing, ChinaWu, Sijie: Evidence-Based Research Center of Social Science &amp; Health, Public Affair School, Nanjing University of Science &amp; Technology, Nanjing, ChinaChi, Iris: Suzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles, CA, US
AN  - 2019-64167-094
AU  - Bai,
AU  - Z.
AU  - Shiga,
AU  - L.
AU  - Luyao,
AU  - Z.
AU  - Wu,
AU  - S.
AU  - Chi,
AU  - I.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jad.2019.09.040
DP  - Ovid Technologies
KW  - Acceptance and Commitment Therapy, Systematic review, Meta-analysis, Depression
KW  - *Age Differences
KW  - *Major Depression
KW  - *Acceptance and Commitment Therapy
KW  - Behavior Therapy &amp; Behavior Modification [3312]
KW  - Human Childhood (birth-12 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older) Young Adulthood (18-29 yrs) Thirties (30-39 yrs) Middle Age (40-64 yrs) Aged (65 yrs &amp; older) Very Old (85 yrs &amp; older)
KW  - Australia, China, Finland, Iran, United Kingdom, Netherlands, Spain, Sweden
L1  - internal-pdf://1479360961/Bai-2020-Acceptance and Commitment Therapy (AC.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2020
SP  - 728-737
T2  - Journal of Affective Disorders
TI  - Acceptance and Commitment Therapy (ACT) to reduce depression: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2019-64167-094
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jad.2019.09.040&amp;issn=0165-0327&amp;isbn=&amp;volume=260&amp;issue=&amp;spage=728&amp;pages=728-737&amp;date=2020&amp;title=Journal+of+Affective+Disorders&amp;atitle=Acceptance+and+Commitment+Therapy+%28ACT%29+to+reduce+depression%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Bai&amp;pid=%3Cauthor%3EBai%2C+Zhenggang%3C%2Fauthor%3E%3CAN%3E2019-64167-094%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/271035/1-s2.0-S0165032719X00154/1-s2.0-S0165032719313023/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEND%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJHMEUCIGqVOnIzEglqaPT%2B517%2B7fu5%2FJUJElTlyLHRbo6HyoM%2FAiEAvDrzlPK4z%2FxWLLqmsx0LJMVQ1qkGzfMNLuVIfV290VEqzwIIKBACGgwwNTkwMDM1NDY4NjUiDNeBDmdgrB6gr3KcCCqsArFHxwKkAseg%2BM5xnQKsbZC20TsBtMjNGvFDs4Hes2TF%2FSGWjffpIUgw05EFvP%2B7YloIPpq1ta2%2BE6d1y%2Fa9c%2FV4xGSBu6wBzc9qLquOzwegRYY0XUY1UdBkryLRHmKM%2BSOhnc%2Fx2z%2BWp2O49O4ze9ev4nc4jqbz%2Fuweps1ofEGmRNqvvaK3enmSvDO3wJ47a5p9XbZ01VkfSQ7JGX%2F3r0YunsS9YY5PDHiHhYAqJZ9RGVMiFSveHyTdXFUDGp%2B2aZW3kJWbdCobTQkPmYUO1wVjhgbM9dNDDKW6YR3V0AEU9d66JJ7S28U82xB30ueppUAH3nqf5JCjo9dR5XLRYsGvsbvmuqSF9%2BLm3YxhDored4c6xScEniCrt164r6z4AHCWeXYZvFmQs7eiPTDF88zvBTrQAmuByFcJQe9Zs3x3IoPCFUwv2HEHhssLNcRxAqWHRrVmtr1453TIa33mQ3vYNFvoN%2FFkaOz2ghGSHyvRzFCQ2uuOHLQvBbsHrP9k0xVE32KhGbe046PYLKxAes8X6HiU2YLzWOIjJJa4fw%2FFUeNaYwci%2FygqpWRJFhU4%2B5HlcYSJFrqpJlZHvUD2Q0iYqQYKdqpL9zDzo2NUVXYqzAd47a5udo4FDfwJr89B3totupWc51mSEy9cClLPaU0Vf%2Bb58CXSa89m%2Bof1hQp7JDb6Jn6zTsRKeIKGU4PrjhoIjWU8JNxIerrWzfW6Z%2BxSHZE8NPiJn6LLK6d%2BuRlVEo2MhhpZpKuzO%2BmPVl5wAZvxbClKfiKPSTVsSiOhLfpJWFkDRLBde2%2FyrVH1lBN52rd5f77ynN2TYnV0nV3CP4K9pCLEzcYlltq6fNI%2BK1WVtenNWQ%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20191213T085921Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYTOH4VYXV%2F20191213%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=24e36d1455ab559040fc0f4d499e4900a189f029007b93001260f6557f5c78f7&amp;hash=0c710ec8b8ba303c87311d99e9f2ccd72c0502affa15593d9e50aa03943edfbf&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0165032719313023&amp;tid=spdf-8ca82009-81cf-49b5-a73c-7b3fe6985cc1&amp;sid=1c47b7374b651743b25aa4713ec30aabc77cgxrqb&amp;type=client
VL  - 260
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Over 600 RCTs have demonstrated the effectiveness of psychosocial interventions for children and young people&#039;s mental health, but little is known about the long-term outcomes. This systematic review sought to establish whether the effects of selective and indicated interventions were sustained at 12 months.

METHOD: 
We conducted a systematic review and meta-analysis focusing on studies reporting medium term outcomes (12 months after end of intervention).

FINDINGS: 
We identified 138 trials with 12-month follow-up data, yielding 165 comparisons, 99 of which also reported outcomes at end of intervention, yielding 117 comparisons. We found evidence of effect relative to control at end of intervention (K = 115, g = 0.39; 95% CI: 0.30-0.47 I2 = 84.19%, N = 13,982) which was maintained at 12 months (K = 165, g = 0.31, CI: 0.25-0.37, I2 = 77.35%, N = 25,652) across a range of diagnostic groups. We explored the impact of potential moderators on outcome, including modality, format and intensity of intervention, selective or indicated intervention, site of delivery, professional/para-professional and fidelity of delivery. We assessed both risk of study bias and publication bias.

CONCLUSIONS: 
Psychosocial interventions provided in a range of settings by professionals and paraprofessionals can deliver lasting benefits. High levels of heterogeneity, moderate to high risk of bias for most studies and evidence of publication bias require caution in interpreting the results. Lack of studies in diagnostic groups such as ADHD and self-harm limit the conclusions that can be drawn. Programmes that increase such interventions&#039; availability are justified by the benefits to children and young people and the decreased likelihood of disorder in adulthood.
AD  - Pilling, Stephen. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Pilling, Stephen. Royal College of Psychiatrists National Collaborating Centre for Mental Health, London, United Kingdom.Fonagy, Peter. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Allison, Elizabeth. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Barnett, Phoebe. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Barnett, Phoebe. Royal College of Psychiatrists National Collaborating Centre for Mental Health, London, United Kingdom.Campbell, Chloe. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Constantinou, Matthew. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Gardner, Tessa. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Lorenzini, Nicolas. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Matthews, Hannah. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Matthews, Hannah. Royal College of Psychiatrists National Collaborating Centre for Mental Health, London, United Kingdom.Ryan, Alana. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Sacchetti, Sofia. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Truscott, Alexandra. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Ventura, Tamara. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Watchorn, Kate. Research Department of Clinical, Educational and Health Psychology, University College London, London, United Kingdom.Whittington, Craig. RWE Literature Synthesis and Biostatistics, Sanofi, Swiftwater, Pennsylvania, United States of America.Kendall, Tim. Royal College of Psychiatrists National Collaborating Centre for Mental Health, London, United Kingdom.
AN  - 33196654
AU  - Pilling,
AU  - S.
AU  - Fonagy,
AU  - P.
AU  - Allison,
AU  - E.
AU  - Barnett,
AU  - P.
AU  - Campbell,
AU  - C.
AU  - Constantinou,
AU  - M.
AU  - Gardner,
AU  - T.
AU  - Lorenzini,
AU  - N.
AU  - Matthews,
AU  - H.
AU  - Ryan,
AU  - A.
AU  - Sacchetti,
AU  - S.
AU  - Truscott,
AU  - A.
AU  - Ventura,
AU  - T.
AU  - Watchorn,
AU  - K.
AU  - Whittington,
AU  - C.
AU  - Kendall,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1371/journal.pone.0236525
DP  - Ovid Technologies
J2  - PLoS ONE
L1  - internal-pdf://0209159298/Pilling-2020-Long-term outcomes of psychologic.pdf
LA  - English
N1  - Pilling, StephenFonagy, PeterAllison, ElizabethBarnett, PhoebeCampbell, ChloeConstantinou, MatthewGardner, TessaLorenzini, NicolasMatthews, HannahRyan, AlanaSacchetti, SofiaTruscott, AlexandraVentura, TamaraWatchorn, KateWhittington, CraigKendall, Tim
PY  - 2020
SP  - e0236525
T2  - PLoS ONE [Electronic Resource]
TI  - Long-term outcomes of psychological interventions on children and young people&#039;s mental health: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33196654
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33196654&amp;id=doi:10.1371%2Fjournal.pone.0236525&amp;issn=1932-6203&amp;isbn=&amp;volume=15&amp;issue=11&amp;spage=e0236525&amp;pages=e0236525&amp;date=2020&amp;title=PLoS+ONE+%5BElectronic+Resource%5D&amp;atitle=Long-term+outcomes+of+psychological+interventions+on+children+and+young+people%27s+mental+health%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Pilling&amp;pid=%3Cauthor%3EPilling+S%3C%2Fauthor%3E%3CAN%3E33196654%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668611/pdf/pone.0236525.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Exposure to trauma during childhood is highly prevalent. This review seeks to evaluate the current state of the literature in regard to trauma-informed care within the school setting. A number of models have been put forth to describe broad trauma-informed approaches integrated within school systems, which incorporate trauma-sensitive care and practices within the broader structure of an organization. The goal of this paper was to systematically review papers detailing relevant interventions to the provision of trauma-informed and trauma-responsive practices within schools. Using a three-tiered system of service delivery as our organizing framework (where the level of support increases across tiers depending on the student&#039;s individual needs), the research that has evaluated the efficacy of traumain-formed interventions is reviewed. Results indicated that much of this work has been exclusively conducted within one level of a three-tiered system that comprises a trauma-informed approach to the school setting. Although there is a foundation of research on interventions applied within specific tiers, few studies have sought to integrate the tiers to test the effectiveness of a fully trauma-informed model within the educational system and most that have integrated the three tiers do not include statistically rigorous evaluations of program effectiveness, such as randomized control trials. A basic model for trauma-informed schools with considerations for intervening directly with students is provided as well as recommendations for future research, which is necessary to inform clear, specific models for fully integrated trauma-informed schools.
AN  - WOS:000514253500056
AU  - Fondren,
AU  - K.
AU  - Lawson,
AU  - M.
AU  - Speidel,
AU  - R.
AU  - McDonnell,
AU  - C.
AU  - G.
AU  - Valentino,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.childyouth.2019.104691
L1  - internal-pdf://4047661229/Fondren-2020.pdf
N1  - Fondren, Kaitlin Lawson, Monica Speidel, Ruth McDonnell, Christina G. Valentino, Kristin1873-7765
PY  - 2020
T2  - Children and Youth Services Review
TI  - Buffering the effects of childhood trauma within the school setting: A systematic review of trauma-informed and trauma-responsive interventions among trauma-affected youth
UR  - &lt;Go to ISI&gt;://WOS:000514253500056
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0190740919308588?via%3Dihub
VL  - 109
ER  -
TY  - JOUR
AB  - Millions of refugees around the globe suffer from posttraumatic stress disorder (PTSD) and/or depression. We conducted a meta-analysis of randomized controlled trials (RCTs) to determine the efficacy of psychological interventions for PTSD and/or depression in refugees. The meta-analysis was registered on the PROSPERO database (CRD42017071384). A search using the Medline, PsycINFO, and PILOTS databases was conducted in January 2019, resulting in 17 RCTs, of which 14 were conducted with adult refugees (1,108 participants) and 3 with young refugees (&lt;18 years; 151 participants). Further inclusion criteria were at least 10 participants completing an active psychological intervention for PTSD, depression, or both and less than 50% of participants receiving concurrent psychotropic drugs. Random effects models showed that active interventions for adult PTSD yielded a medium to large aggregated effect size (g = 0.77; 95% confidence interval [CI] [0.26, 1.28]) at posttreatment when compared with passive and active control conditions. Active interventions for adult depression also produced large controlled effect sizes at posttreatment (g = 0.82; 95% CI [0.24, 1.40]). The effects appeared to persist over the average follow-up period of 6 months. The findings suggest that psychological interventions can effectively reduce symptoms of both PTSD and depression in adult refugees. However, the considerable heterogeneity between studies indicates that the efficacy may vary significantly. Future studies should aim to explore the substantial heterogeneity in effect sizes between studies with adult refugees. Additionally, more trials with young refugees suffering from PTSD or depression are needed to determine treatment efficacy for this population.
AN  - 32191370
AU  - Kip,
AU  - A.
AU  - Priebe,
AU  - S.
AU  - Holling,
AU  - H.
AU  - Morina,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/cpp.2446
L1  - internal-pdf://2933311037/Kip-2020-Psychological interventions for postt.pdf
PY  - 2020
SP  - 489-503
T2  - Clinical Psychology &amp; Psychotherapy
TI  - Psychological interventions for posttraumatic stress disorder and depression in refugees: A meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=32191370
UR  - https://onlinelibrary.wiley.com/doi/10.1002/cpp.2446
VL  - 27
ER  -
TY  - JOUR
AB  - Anxiety disorders are among the most common youth mental health disorders. Early intervention can reduce elevated anxiety symptoms. School-based interventions exist but it is unclear how effective targeted approaches are for reducing symptoms of anxiety. This review and meta-analysis aimed to determine the effectiveness of school-based indicated interventions for symptomatic children and adolescents. The study was registered with PROSPERO [CRD42018087628]. We searched MEDLINE, EMBASE, PsycINFO, and the Cochrane Library for randomised-controlled trials comparing indicated programs for child and adolescent (5-18 years) anxiety to active or inactive control groups. Data were extracted from papers up to December 2019. The primary outcome was efficacy (mean change in anxiety symptom scores). Sub-group and sensitivity analyses explored intervention intensity and control type. We identified 20 studies with 2076 participants. Eighteen studies were suitable for meta-analysis. A small positive effect was found for indicated programs compared to controls on self-reported anxiety symptoms at post-test (g = - 0.28, CI = - 0.50, - 0.05, k = 18). This benefit was maintained at 6 (g = - 0.35, CI = - 0.58, - 0.13, k = 9) and 12 months (g = - 0.24, CI = - 0.48, 0.00, k = 4). Based on two studies, &gt; 12 month effects were very small (g = - 0.01, CI = - 0.38, 0.36). No differences were found based on intervention intensity or control type. Risk of bias and variability between studies was high (I&lt;sup&gt;2&lt;/sup&gt; = 78%). Findings show that school-based indicated programs for child and adolescent anxiety can produce small beneficial effects, enduring for up to 12 months. Future studies should include long-term diagnostic assessments.
AD  - Hugh-Jones, Siobhan. School of Psychology, University of Leeds, Leeds, LS2 9JT, UK. s.hugh-jones@leeds.ac.uk.Beckett, Sophie. The Barberry National Centre for Mental Health, University of Birmingham, Birmingham, B15 2FG, UK.Tumelty, Ella. The Barberry National Centre for Mental Health, University of Birmingham, Birmingham, B15 2FG, UK.Mallikarjun, Pavan. The Barberry National Centre for Mental Health, University of Birmingham, Birmingham, B15 2FG, UK.
AN  - 32535656
AU  - Hugh-Jones,
AU  - S.
AU  - Beckett,
AU  - S.
AU  - Tumelty,
AU  - E.
AU  - Mallikarjun,
AU  - P.
DA  - Jun 13
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-020-01564-x
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
L1  - internal-pdf://1926474828/Hugh-Jones-2020-Indicated prevention intervent.pdf
LA  - English
N1  - Using Smart Source ParsingJunHugh-Jones, SiobhanBeckett, SophieTumelty, EllaMallikarjun, Pavan
PY  - 2020
SP  - 13
T2  - European Child &amp; Adolescent Psychiatry
TI  - Indicated prevention interventions for anxiety in children and adolescents: a review and meta-analysis of school-based programs
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32535656
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32535656&amp;id=doi:10.1007%2Fs00787-020-01564-x&amp;issn=1018-8827&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=Indicated+prevention+interventions+for+anxiety+in+children+and+adolescents%3A+a+review+and+meta-analysis+of+school-based+programs.&amp;aulast=Hugh-Jones&amp;pid=%3Cauthor%3EHugh-Jones+S%3C%2Fauthor%3E%3CAN%3E32535656%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s00787-020-01564-x.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - Paraprofessionals report spending a substantial amount of time addressing challenging behavior in a range of school environments, yet identify behavioral intervention as a high-priority training area. The purpose of this meta-analysis was to systematically review and summarize single-case intervention studies involving paraprofessional-delivered behavioral interventions for students with disabilities. Descriptive findings suggest that, among the reviewed studies, paraprofessionals primarily provided behavioral support to students with autism spectrum disorder, intellectual disability, and multiple disabilities who engage in a wide range of challenging behaviors in both inclusive and noninclusive school environments. Overall, training largely was delivered by researchers and resulted in positive paraprofessional implementation outcomes. Likewise, paraprofessional-implemented behavioral interventions contributed to desirable changes in student challenging and appropriate behavior, with effect size estimates significantly higher for interventions delivered to early childhood-age students and within inclusive school settings. Implications for practice, limitations, and future research directions are described.
AN  - WOS:000524420100001
AU  - Walker,
AU  - V.
AU  - L.
AU  - Carpenter,
AU  - M.
AU  - E.
AU  - Lyon,
AU  - K.
AU  - J.
AU  - Button,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/1098300720911147
L1  - internal-pdf://0149398263/Walker.pdf
N1  - Walker, Virginia L. Carpenter, Megan E. Lyon, Kristin J. Button, LindseyWalker, Virginia/0000-0003-3248-72901538-4772
PY  - 2020
T2  - Journal of Positive Behavior Interventions
TI  - A Meta-Analysis of Paraprofessional-Delivered Interventions to Address Challenging Behavior Among Students With Disabilities
UR  - &lt;Go to ISI&gt;://WOS:000524420100001
UR  - https://journals.sagepub.com/doi/10.1177/1098300720911147
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1098300720911147
ER  -
TY  - JOUR
AB  - **Background:** 
Depression is a common threat to children and adolescents in terms of affecting psychosocial development and increasing their risk of suicide. Apart from conventional treatments for depression, physical exercise has become a promising alternative. This paper aims to systematically review the existing meta-analyses that focus on the impact of physical exercise on clinical and nonclinical depression in children and adolescents.

**Methods:** 
A systematic literature search was conducted using PsycINFO, PsycARTICLES, MedLine, PubMed, and hand searching. Risk of bias analysis, effect sizes calculations, and evaluation of the methodological characteristics (AMSTAR 2) were carried out.

**Results:** 
Four meta-analyses met the inclusion criteria. After analysing the overlap, the total sample contained 30 single studies (mostly including gender mixed samples) and 2,110 participants (age range 5-20 years). The medium duration of the interventions was 11.5 weeks. The sessions had a medium length of 41 min, and the frequency of implementation was three sessions per week. The most implemented intervention type was aerobic exercise, while control groups mainly continued with their regular routine, among other related options. The overall mean effect of physical exercise on depression was medium (d = -0.50). The additional analysis in clinically depressed samples documented a small to medium mean effect (d = -0.48) in favor of the intervention.

**Conclusion:** The small to medium but consistently positive effects that were found in the present study place physical exercise as a promising and helpful alternative for children and adolescents with clinical and nonclinical depression. The limited literature focused on children and adolescents in comparison with adult samples points to the need for further research.
AD  - Wegner, Mirko. Institute of Sport Science, Humboldt-Universitat zu Berlin, Berlin, Germany.Amatriain-Fernandez, Sandra. Faculty of Sport Sciences and Physical Education, University of A Coruna, A Coruna, Spain.Kaulitzky, Andrea. Faculty of Human Sciences, Department of Pedagogy, Medical School Hamburg, Hamburg, Germany.Murillo-Rodriguez, Eric. School of Medicine, Anahuac Mayab University, Merida, Yucatan, Mexico.Machado, Sergio. Laboratory of Physical Activity Neuroscience, Physical Activity Sciences Postgraduate Program, Salgado de Oliveira University, Niteroi, Brazil.Budde, Henning. Faculty of Human Sciences, Department of Pedagogy, Medical School Hamburg, Hamburg, Germany.
AN  - 32210847
AU  - Wegner,
AU  - M.
AU  - Amatriain-Fernandez,
AU  - S.
AU  - Kaulitzky,
AU  - A.
AU  - Murillo-Rodriguez,
AU  - E.
AU  - Machado,
AU  - S.
AU  - Budde,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyt.2020.00081
DP  - Ovid Technologies
J2  - Front Psychiatr
L1  - internal-pdf://1936244962/Wegner-2020-Systematic Review of Meta-Analyses.pdf
LA  - English
M3  - Systematic Review
N1  - Wegner, MirkoAmatriain-Fernandez, SandraKaulitzky, AndreaMurillo-Rodriguez, EricMachado, SergioBudde, Henning
PY  - 2020
SP  - 81
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Systematic Review of Meta-Analyses: Exercise Effects on Depression in Children and Adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32210847
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32210847&amp;id=doi:10.3389%2Ffpsyt.2020.00081&amp;issn=1664-0640&amp;isbn=&amp;volume=11&amp;issue=&amp;spage=81&amp;pages=81&amp;date=2020&amp;title=Frontiers+in+psychiatry+Frontiers+Research+Foundation&amp;atitle=Systematic+Review+of+Meta-Analyses%3A+Exercise+Effects+on+Depression+in+Children+and+Adolescents.&amp;aulast=Wegner&amp;pid=%3Cauthor%3EWegner+M%3C%2Fauthor%3E%3CAN%3E32210847%3C%2FAN%3E%3CDT%3ESystematic+Review%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068196/pdf/fpsyt-11-00081.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Importance:** 
It is not clear whether psychotherapies for depression have comparable effects across the life span. Finding out is important from a clinical and scientific perspective.

**Objective:** 
To compare the effects of psychotherapies for depression between different age groups.

**Data Sources:** 
Four major bibliographic databases (PubMed, PsychINFO, Embase, and Cochrane) were searched for trials comparing psychotherapy with control conditions up to January 2019.

**Study Selection:** 
Randomized trials comparing psychotherapies for depression with control conditions in all age groups were included.

**Data Extraction and Synthesis:** 
Effect sizes (Hedges g) were calculated for all comparisons and pooled with random-effects models. Differences in effects between age groups were examined with mixed-effects subgroup analyses and in meta-regression analyses.

**Main Outcomes and Measures:** 
Depressive symptoms were the primary outcome.

**Results:** 
After removing duplicates, 16756 records were screened and 2608 full-text articles were screened. Of these, 366 trials (36702 patients) with 453 comparisons between a therapy and a control condition were included in the qualitative analysis, including 13 (3.6%) in children (13 years and younger), 24 (6.6%) in adolescents (&gt;=13 to 18 years), 19 (5.2%) in young adults (&gt;=18 to 24 years), 242 (66.1%) in middle-aged adults (&gt;=24 to 55 years), 58 (15.8%) in older adults (&gt;=55 to 75 years), and 10 (2.7%) in older old adults (75 years and older). The overall effect size of all comparisons across all age groups was g = 0.75 (95% CI, 0.67-0.82), with very high heterogeneity (I2 = 80%; 95% CI: 78-82). Mean effect sizes for depressive symptoms in children (g = 0.35; 95% CI, 0.15-0.55) and adolescents (g = 0.55; 95% CI, 0.34-0.75) were significantly lower than those in middle-aged adults (g = 0.77; 95% CI, 0.67-0.87). The effect sizes in young adults (g = 0.98; 95% CI, 0.79-1.16) were significantly larger than those in middle-aged adults. No significant difference was found between older adults (g = 0.66; 95% CI, 0.51-0.82) and those in older old adults (g = 0.97; 95% CI, 0.42-1.52). The outcomes should be considered with caution because of the suboptimal quality of most of the studies and the high levels of heterogeneity. However, most primary findings proved robust across sensitivity analyses, addressing risk of bias, target populations included, type of therapy, diagnosis of mood disorder, and method of data analysis.

**Conclusions and Relevance:** 
Trials included in this meta-analysis reported effect sizes of psychotherapies that were smaller in children than in adults, probably also smaller in adolescents, that the effects may be somewhat larger in young adults, and without meaningful differences between middle-aged adults, older adults, and older old adults.
AD  - Cuijpers, Pim. Department of Clinical, Neuro, and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.Karyotaki, Eirini. Department of Clinical, Neuro, and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.Eckshtain, Dikla. Massachusetts General Hospital, Department of Psychiatry, Harvard Medical School, Boston.Ng, Mei Yi. Department of Psychology and Center for Children and Families, Florida International University, Miami.Corteselli, Katherine A. Department of Psychology, Harvard University, Cambridge, Massachusetts.Noma, Hisashi. Department of Data Science, The Institute of Statistical Mathematics, Tokyo, Japan.Quero, Soledad. Department of Basic, Clinical Psychology and Psychobiology, Universitat Jaume I, Castellon, Spain.Weisz, John R. Department of Psychology, Harvard University, Cambridge, Massachusetts.
AN  - 32186668
AU  - Cuijpers,
AU  - P.
AU  - Karyotaki,
AU  - E.
AU  - Eckshtain,
AU  - D.
AU  - Ng,
AU  - M.
AU  - Y.
AU  - Corteselli,
AU  - K.
AU  - A.
AU  - Noma,
AU  - H.
AU  - Quero,
AU  - S.
AU  - Weisz,
AU  - J.
AU  - R.
DA  - Mar 18
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1001/jamapsychiatry.2020.0164
DP  - Ovid Technologies
J2  - JAMA Psychiatry
L1  - internal-pdf://2570719532/Cuijpers-2020-Psychotherapy for Depression Acr.pdf
LA  - English
N1  - Using Smart Source ParsingMarCuijpers, PimKaryotaki, EiriniEckshtain, DiklaNg, Mei YiCorteselli, Katherine ANoma, HisashiQuero, SoledadWeisz, John R
PY  - 2020
SP  - 18
T2  - JAMA Psychiatry
TI  - Psychotherapy for Depression Across Different Age Groups: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32186668
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32186668&amp;id=doi:10.1001%2Fjamapsychiatry.2020.0164&amp;issn=2168-622X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=JAMA+Psychiatry&amp;atitle=Psychotherapy+for+Depression+Across+Different+Age+Groups%3A+A+Systematic+Review+and+Meta-analysis.&amp;aulast=Cuijpers&amp;pid=%3Cauthor%3ECuijpers+P%3C%2Fauthor%3E%3CAN%3E32186668%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://jamanetwork.com/journals/jamapsychiatry/articlepdf/2762981/jamapsychiatry_cuijpers_2020_oi_200004.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - In consideration of the adverse societal, physical, and psychological impacts of bullying on a child&#039;s development and future, many studies have developed anti-bullying programs and educational interventions to curb bullying occurrences. Therefore, this systematic review aimed to examine the effectiveness of such educational interventions at reducing the frequencies of traditional bullying or cyberbullying and cybervictimization among adolescents. A comprehensive search was conducted using PubMed, Embase, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, Google Scholar, and ProQuest Dissertations and Theses. Only quantitative studies that reported the effects of educational interventions on reducing the frequencies of traditional bullying or cyberbullying victimization and perpetration were included. Seventeen studies (N &lt;sub&gt;total&lt;/sub&gt; = 35,694 adolescents, Range&lt;sub&gt;child age&lt;/sub&gt; = 10-18 years) were finalized, and meta-analyses were conducted using a random effect model. Overall, the existing educational interventions had very small to small effect sizes on traditional bullying and cyberbullying perpetration (traditional: standardized mean differences [SMD] = -.30 and cyber: SMD = -.16) and victimization (traditional: SMD = -18 and cyber: SMD = -.13) among adolescents. Type of intervention (i.e., whole school-based or classroom-based), program duration, and presence of parental involvement did not moderate program effectiveness, but cyberbullying programs were more effective when delivered by technology-savvy content experts compared to teachers. Since existing educational interventions were marginally effective in reducing bullying frequencies, further research is needed to identify key moderators that enhance educational programs or develop alternative forms of anti-bullying interventions.
AD  - Ng, Esperanza Debby. Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.Chua, Joelle Yan Xin. KK Women&#039;s and Children&#039;s Hospital, Singapore.Shorey, Shefaly. Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
AN  - 32588769
AU  - Ng,
AU  - E.
AU  - D.
AU  - Chua,
AU  - J.
AU  - Y.
AU  - X.
AU  - Shorey,
AU  - S.
DA  - Jun 26
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1524838020933867
DP  - Ovid Technologies
J2  - Trauma Violence Abuse Rev J
L1  - internal-pdf://2063183236/Ng-2020-The Effectiveness of Educational Inter.pdf
LA  - English
N1  - Ng, Esperanza DebbyChua, Joelle Yan XinShorey, Shefaly
PY  - 2020
SP  - 1524838020933867
T2  - Trauma Violence &amp; Abuse
TI  - The Effectiveness of Educational Interventions on Traditional Bullying and Cyberbullying Among Adolescents: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32588769
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32588769&amp;id=doi:10.1177%2F1524838020933867&amp;issn=1524-8380&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1524838020933867&amp;pages=1524838020933867&amp;date=2020&amp;title=Trauma+Violence+%26+Abuse&amp;atitle=The+Effectiveness+of+Educational+Interventions+on+Traditional+Bullying+and+Cyberbullying+Among+Adolescents%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Ng&amp;pid=%3Cauthor%3ENg+ED%3C%2Fauthor%3E%3CAN%3E32588769%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1524838020933867
ER  -
TY  - JOUR
AB  - AIM: The aim of this review was to evaluate the evidence for interventions for behavioural sleep problem in infants.

METHODS: Systematic review based on a search in MEDLINE, Web of Science and PsychINFO in December 2017 for articles published in English during 2007-2017 about preventive and treatment interventions for sleep problems in infants. The review included controlled trials and meta-analyses with at least 20 infants in study groups assessed according to the Grading of Recommendations Assessment, Development and Evaluation criteria.

RESULTS: Out of 476 original articles assessed for eligibility, 12 studies were included in the synthesis. Interventions with behavioural, educational and massage strategies were evaluated. No intervention was evaluated in more than one trial. Five interventions with behavioural methods for establishing consistent routines or controlled crying showed modest short-term effects, while the evidence for elements of education was inconsistent. Studies of massage were of poor quality. Knowledge gaps were identified regarding interventions in cross-cultural context, involving fathers, in children below six months of age, in high-risk populations and consequences of interventions that include extinction.

CONCLUSION: Some support for short-term effects of behavioural treatment strategies was found, but more studies are needed to establish evidence.
AD  - Reuter, Antonia. Child and Youth Healthcare, Region Vastra Gotaland, Gothenburg, Sweden.Silfverdal, Sven-Arne. Clinical Sciences, Pediatrics, Umea University, Umea, Sweden.Silfverdal, Sven-Arne. Centre for Mother and Child Health Care, Umea, Sweden.Lindblom, Kristin. Child Health Services, Falun, Sweden.Hjern, Anders. Sachs&#039; Children and Youth hospital, Stockholm, Sweden.Hjern, Anders. Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden.Hjern, Anders. CHESS, Centre for Health Equity Studies, Stockholm University and Karolinska Institutet, Stockholm, Sweden.
AN  - 31965638
AU  - Reuter,
AU  - A.
AU  - Silfverdal,
AU  - S.
AU  - A.
AU  - Lindblom,
AU  - K.
AU  - Hjern,
AU  - A.
DA  - August
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/apa.15182
DP  - Ovid Technologies
J2  - Acta Paediatr
L1  - internal-pdf://4133042774/Reuter_et_al-2020-Acta_Paediatrica.pdf
internal-pdf://2428845052/Reuter-2020-A systematic review of prevention.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingJanReuter, AntoniaSilfverdal, Sven-ArneLindblom, KristinHjern, Anders
PY  - 2020
SP  - 22
T2  - Acta Paediatrica
TI  - A systematic review of prevention and treatment of infant behavioural sleep problems
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31965638
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31965638&amp;id=doi:10.1111%2Fapa.15182&amp;issn=0803-5253&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Acta+Paediatrica&amp;atitle=A+systematic+review+of+prevention+and+treatment+of+infant+behavioural+sleep+problems.&amp;aulast=Reuter&amp;pid=%3Cauthor%3EReuter+A%3C%2Fauthor%3E%3CAN%3E31965638%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/apa.15182
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/apa.15182?download=true
VL  - 22
ER  -
TY  - JOUR
AB  - This meta-analysis aimed at providing an up-to-date estimate on the efficacy of psychological interventions for pediatric PTSD and to analyze the association between treatment efficacy and study quality. We systematically searched PsycINFO, Medline and recent meta-analyses for randomized controlled trials (RCTs). RCTs were eligible if a) they included at least 10 participants per group, b) compared a psychological intervention to a control condition or another psychological intervention and c) mean age was below 19 years. Study quality was assessed independently by both authors on the basis of eight quality criteria. We explored the potential associations between study quality and effect sizes in three ways. Firstly, we compared effect-sizes of high-quality vs. lower-quality studies. Secondly, we analyzed study quality as a continuous predictor of effect sizes. And thirdly, we examined the relationship between the eight individual quality criteria and effect sizes. A total of 46 eligible RCTs were included in the meta-analysis. Psychological interventions produced a large effect size when compared to waitlist (g = 1.07, k = 23, NNT = 1.81) and a medium effect size when compared to active control conditions (g = 0.60, k = 15, NNT = 3.03) at post-treatment. Overall, study quality was moderate. Comparisons of high-quality trials (k = 16) with lower-quality trials (k = 30) produced only non-significant findings in main-analyses as well as moderator sub-analyses. Study quality as a continuous variable was also not found to be related to effect sizes in any of the main analyses, nor was any of the eight individual quality criteria. The summary of the available literature strongly suggests that psychological interventions are effective in treating PTSD in children and adolescents. No significant associations between study quality and treatment efficacy were observed.
AD  - Hoppen, Thole H. University of Munster, Institute of Psychology, Fliednerstr. 21, 48149 Munster, Germany. Electronic address: thoppen@uni-muenster.de.Morina, Nexhmedin. University of Munster, Institute of Psychology, Fliednerstr. 21, 48149 Munster, Germany. Electronic address: morina@uni-muenster.de.
AN  - 32361507
AU  - Hoppen,
AU  - T.
AU  - H.
AU  - Morina,
AU  - N.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.cpr.2020.101855
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://1753774381/Hoppen-2020-Is high-quality of trials associat.pdf
LA  - English
M3  - Review
N1  - Hoppen, Thole HMorina, NexhmedinS0272-7358(20)30043-X
PY  - 2020
T2  - Clinical Psychology Review
TI  - Is high-quality of trials associated with lower treatment efficacy? A meta-analysis on the association between study quality and effect sizes of psychological interventions for pediatric PTSD
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32361507
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32361507&amp;id=doi:10.1016%2Fj.cpr.2020.101855&amp;issn=0272-7358&amp;isbn=&amp;volume=78&amp;issue=&amp;spage=101855&amp;pages=101855&amp;date=2020&amp;title=Clinical+Psychology+Review&amp;atitle=Is+high-quality+of+trials+associated+with+lower+treatment+efficacy%3F+A+meta-analysis+on+the+association+between+study+quality+and+effect+sizes+of+psychological+interventions+for+pediatric+PTSD.&amp;aulast=Hoppen&amp;pid=%3Cauthor%3EHoppen+TH%3C%2Fauthor%3E%3CAN%3E32361507%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/271858/1-s2.0-S0272735820X00043/1-s2.0-S027273582030043X/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEK%2F%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQCYoch3fid2vjt1VYQPaP6elzGCPiGV78zYUWYXgV%2BXAQIhANWgO4W5eJfjDGYhN0%2FeHbyZX6LvQladuEm6SjYwpQ%2B0KrQDCCcQAxoMMDU5MDAzNTQ2ODY1IgydQRk7X7x0VmoMHZ4qkQMU62TSERz3puAvjg0HzBQ9f3fY5rgIpUDGanvdTI%2FZy%2BhCKku9LlHGYokyyM517hnNhRpsFvKLhk4Hb659sB5aUyorqNlJZnTQtIbhTTuJ7DbTTM2P8yqXSidy3miulgFAB4xqb5XowHbW24GArycot%2BADcuWD1ApkrJqj1QRYnWnVAWTWR3r88BpdMY45PxXjj3JwkNLilzXePc4n4sebzcJuHMLrg8nfUk53qgLfWF3QvVGTLJXYEVYb8hUs%2F0vUjGyp7csYSyCwm4H7YJmpH7V5y56ndFSvHA8Gmt62SyK%2B13%2Bn5XdCf6AMwFeKfwWXreVycvl%2BLFq51QIhE7eOfZhQbskUA4lTntvW%2FieSInmJlToU4s6%2F5REol3gvJAYvYopF8pnmapmlzjt2bdoHmyxWL2HVPA2Z3yN3YXk4Jv%2FZ5Y8OaaT%2FGNriuy8MsfH17lW17J5QCfDotnA%2FMCZy9Dp90pHhWXObx1WNZ%2F4NIESDW1QlJsxRWRFkTQAoGyTPcVBzsN2TEjVKhdigRMJFYjDz8IH3BTrqAQhgypEe6AC%2BYG16tBTY3uAeKMY4hnzxJPAFiJho6KNU5r1te44Wdhwd5QrAZPKLasdG%2FTm7gwv%2BeFmXsQVIyuPVJJhCnxjrSoSF%2FYF4lUo%2FOOpJtg0vZVfd6%2B7WH0EFIqh95L49DUA4A6SgrJvELadvlAywAq0DujY%2FDglzfxhb2UqvEL%2FGgGMqPfAuZRTvHD7DGiq3vfmPNZT4CapZCm5HaQmmAo%2ByiO6a7TjxTDIkWW5eY810eUa4%2BefZQMJBBk7fKc5fbvYXTSoUM24LmqMv%2BtrOkb4kTAA216yDSIQfAUwX%2F3iEymfc5A%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200610T065437Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY5EMXBNDQ%2F20200610%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=ea341b1e093581e02a85a2c36efd573a4414155784632e6b0b7d966481040641&amp;hash=2f438ffa0d49f31ce190a167f43fc07e3310e092840aef8535a06cce255597b1&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S027273582030043X&amp;tid=spdf-60ba26b7-e5e3-49d3-8c6d-73c059fbb0bf&amp;sid=b6715d5b8d7fc143477ae8442de16298848bgxrqb&amp;type=client
VL  - 78
ER  -
TY  - JOUR
AB  - Peer reporting interventions (i.e., Positive Peer Reporting and tootling) are commonly used peer-mediated interventions in schools. These interventions involve training students to make reports about peers&#039; prosocial behaviors, whether in oral or written form. Although peer reporting interventions have been included in meta-analyses of group contingencies, this study is the first meta-analytic review of single-case research focusing exclusively on peer reporting interventions. The literature search and application of inclusion criteria yielded 21 studies examining the impact of a peer reporting intervention on student behavior compared to baseline conditions. All studies used single-case experimental designs including at least three demonstrations of an effect and at least three data points per phase. Several aspects of studies, participants, and interventions were coded. Log response ratios and Tau were calculated as effect size estimates. Effect size estimates were synthesized in a multi-level meta-analysis with random effects for (a) studies and (b) cases within studies. Overall results indicated peer reporting interventions had a non-zero and positive impact on student outcomes. This was also true when data were subset by outcome (i.e., disruptive behavior, academically engaged behavior, and social behavior). Results were suggestive of more between- than within-study variability. Moderator analyses were conducted to identify aspects of studies, participants, or peer reporting interventions associated with differential effectiveness. Moderator analyses suggested published studies were associated with higher effect sizes than unpublished studies (i.e., theses/dissertations). This meta-analysis suggests peer reporting interventions are effective in improving student behavior compared to baseline conditions. Implications and directions for future investigation are discussed.
AN  - 33276857
AU  - Collins,
AU  - T.
AU  - A.
AU  - Drevon,
AU  - D.
AU  - D.
AU  - Brown,
AU  - A.
AU  - M.
AU  - Villarreal,
AU  - J.
AU  - N.
AU  - Newman,
AU  - C.
AU  - L.
AU  - Endres,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jsp.2020.10.002
L1  - internal-pdf://1676724336/Collins-2020-Say something nice_ A meta-analyt.pdf
PY  - 2020
SP  - 89-103
T2  - Journal of School Psychology
TI  - Say something nice: A meta-analytic review of peer reporting interventions
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=33276857
VL  - 83
ER  -
TY  - JOUR
AB  - STUDY OBJECTIVES: 
Sleep disturbances are common and associated with negative functional and health consequences in children with neurological and neurodevelopmental disorders (NNDDs), and represent an important potential target for behavioral interventions. This systematic review examined the efficacy of behavioral sleep interventions (BSIs) for children with NNDDs and comorbid sleep disturbances.

METHODS: 
A systematic search of MEDLINE, EMBASE, PsychINFO, and CENTRAL was conducted in April 2019. Randomized controlled trials (RCTs) of BSI for children with NNDDS were included. Meta-analysis and GRADE quality ratings were performed on sleep and secondary functional outcomes (cognition, academics, behavior).

RESULTS: 
Nine RCTs were identified (n=690; Mage=8.39+/-2.64years; 71.11% male). Largely moderate level evidence for post-treatment improvements in sleep were found on (i) subjectively reported sleep disturbances (total sleep disturbance [SMD=0.89], night wakings [SMD=0.52], bedtime resistance [SMD=0.53], parasomnias [SMD=0.34], sleep anxiety [SMD=0.50]), subjectively reported sleep patterns (sleep duration [SMD=0.30], sleep onset duration [SMD=0.75]) and (ii) objectively measured actigraphic sleep patterns (total sleep time [MD=18.09 mins; SMD=0.32], sleep onset latency [MD=11.96 mins; SMD=0.41]). Improvements in sleep (subjective, not actigraphy) were maintained at follow-up, but few studies conducted follow-up assessments resulting in low quality evidence. Reduction in total behavioral problems (SMD=0.48) post-treatment, and attention/hyperactivity (SMD=0.28) at follow-up were found. Changes in cognition and academic skills were not examined in any studies.

CONCLUSIONS: 
BSIs improve sleep, at least in the short-term, in children with NNDDs. Benefits may extend to functional improvements in behavior. More rigorous RCTs involving placebo-controls, blinded outcome assessment, longer follow-up durations, and assessment of functional outcomes are required.
AD  - Phillips, Natalie L. School of Psychology, University of Sydney, Sydney, Australia.Moore, Teleri. School of Psychology, University of Sydney, Sydney, Australia.Teng, Arthur. Department of Sleep Medicine, Sydney Children&#039;s Hospital (Randwick), Sydney, Australia.Teng, Arthur. Faculty of Medicine, University of New South Wales, Sydney, Australia.Brookes, Naomi. Brain Injury Rehabilitation Program, Sydney Children&#039;s Hospital (Randwick), Sydney, Australia.Palermo, Tonya M. Center for Child Health, Behavior and Development, Seattle Children&#039;s Research Institute, Seattle, Washington, USA.Palermo, Tonya M. Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, Washington, USA.Lah, Suncica. School of Psychology, University of Sydney, Sydney, Australia.
AN  - 32163581
AU  - Phillips,
AU  - N.
AU  - L.
AU  - Moore,
AU  - T.
AU  - Teng,
AU  - A.
AU  - Brookes,
AU  - N.
AU  - Palermo,
AU  - T.
AU  - M.
AU  - Lah,
AU  - S.
DA  - Mar 12
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/sleep/zsaa040
DP  - Ovid Technologies
J2  - Sleep
L1  - internal-pdf://0520887399/Phillips-2020.pdf
LA  - English
N1  - Using Smart Source ParsingMarPhillips, Natalie LMoore, TeleriTeng, ArthurBrookes, NaomiPalermo, Tonya MLah, Suncicazsaa040
PY  - 2020
SP  - 12
T2  - Sleep
TI  - Behavioral Interventions for Sleep Disturbances in Children with Neurological and Neurodevelopmental Disorders: A Systematic Review and Meta-analysis of Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32163581
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32163581&amp;id=doi:10.1093%2Fsleep%2Fzsaa040&amp;issn=0161-8105&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Sleep&amp;atitle=Behavioral+Interventions+for+Sleep+Disturbances+in+Children+with+Neurological+and+Neurodevelopmental+Disorders%3A+A+Systematic+Review+and+Meta-analysis+of+Randomized+Controlled+Trials.&amp;aulast=Phillips&amp;pid=%3Cauthor%3EPhillips+NL%3C%2Fauthor%3E%3CAN%3E32163581%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://academic.oup.com/sleep/article-abstract/doi/10.1093/sleep/zsaa040/5804209?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/zsaa040.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAn0wggJ5BgkqhkiG9w0BBwagggJqMIICZgIBADCCAl8GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMo_bqzR2Qz7fLjqmVAgEQgIICMMG_0UnKbCsQeffnXP5fJo9XXIYUDmikwCVpqRIOAtCfjFXHd00u833kywBPrjbh_3CkHfv56Gjoc5F2tzdckpQwbOEa7IfYK8mLz0venCup-bUDQRGDFoRJtWfOlhWO4174D92VLgQbhB5pikRHTA9ZCzQrXEfNcDEaBqYuhNqM-Js6ta0BoKTrYTEwTjqSLofnx4KefEHTkIkuah_19DCEOy-My3macYUF0ojF4HOlzgaHzfx1Btl-7N-fRkW7JpM1aIjfbnPlyDDK_LQYqjzu7e66J1Dk0cy8PT8RGgvoXRX1bBijxRSOdLrl1TfQ3uN4atF9TSjv0wmujcasHqoBqsu7gqwibYJXh6rgxyj0IIRtzlUNES4rZxsYw-hdTXLzTJiNedJRYgw-5k_F_W9OOIZiSTQDyM61SMWFKiUvYV7td4jEy_rv1k6z6BpLK2OA5XjSVCMfDE-b5pNJm1CoYzNPS77ePBBxdjOxWHVfTS3hFkh-omS1xdWncbVL_B_QeFioTwpjk45eiE0Aky2hBph6FT_Tnu_vVM6kCVDjDu8igxCCAXlV8zC8owc-Bz91HGVOcU8TAzh9CM7Rreh34IcG5PVLHayMV1Z2tdeSQR_WbQma1rReFwWLf0g_7FajcrLeIUrTzt9v6_acwtLnKilF7j7vbZRc_BKSg-ph0_gO0i8dwByd4mdZj0qCPMAD3zMljrmMrKy3dvEercXNJBm2K5XFKQHcNwPh0WEr
VL  - 12
ER  -
TY  - JOUR
AB  - **Aim:** 
To synthesize the existing literature and determine the efficacy of neonatal therapy, starting in the neonatal intensive care unit (NICU), on the motor, cognitive, and behavioral outcomes of infants born preterm. 

**Method:** 
Databases were searched for randomized controlled trials or quasi-randomized controlled trials of direct therapy early intervention for infants with a gestational age of less than 37 weeks, initiated in the NICU and delivered by a therapist or parent with therapist support. Quality was evaluated using the Cochrane standardized risk of bias assessment tool. Recommendations were made using the Grading of Recommendations, Assessment, Development and Evaluations approach. 

**Results:** 
Fifteen studies met the inclusion criteria. Studies were categorized into four intervention categories: (1) parent-delivered motor intervention (PDMI); (2) therapist-delivered postural control intervention (TDPCI); (3) developmental care; and (4) oromotor intervention. Risk of bias varied from low (10 studies) to high (three studies) or was unclear (two studies). 

**Interpretation:** 
Preliminary support indicates that daily PDMI improves motor and cognitive outcomes in the short-term and possibly long-term. TDPCI is effective in promoting short-term gains in motor development. Developmental care programs designed by a neonatal therapist appear to be effective in improving short-term behavior but are inconclusive for motor and cognitive outcomes or long-term behavioral outcomes. Regarding oromotor interventions, there is insufficient research to be confident in their efficacy on improving developmental outcomes. What this paper adds Parent-delivered motor interventions (PDMIs) are more effective in improving motor and cognitive outcomes than other interventions. Preliminary support indicates that daily PDMI improves motor and cognitive outcomes in the short- and possibly long-term. Therapist-delivered postural control interventions are effective in promoting short-term gains in motor development. Developmental care programs designed by a neonatal therapist are effective in improving the short-term behavior of infants born preterm. Oral motor interventions were found to have no effect on improving developmental outcomes. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - Dusing, Stacey C.: scdusing@vcu.eduDusing, Stacey C.: Department of Physical Therapy, Motor Development Lab, Virginia Commonwealth University, 900 East Leigh Street, Richmond, VA, US, 23298, scdusing@vcu.eduKhurana, Sonia: Motor Development Lab, Department of Physical Therapy, College of Health Professions, Virginia Commonwealth University, Richmond, VA, USKane, Audrey E.: Department of Occupational Therapy, College of Health Professions, Virginia Commonwealth University, Richmond, VA, USBrown, Shaaron E.: Physical Therapy Department, Virginia Commonwealth University Health, Children&#039;s Hospital of Richmond, Virginia Commonwealth University, Richmond, VA, USTarver, Talicia: Tompkins-McCaw Library for the Health Sciences, Virginia Commonwealth University Libraries, Richmond, VA, USDusing, Stacey C.: Motor Development Lab, Department of Physical Therapy, College of Health Professions, Virginia Commonwealth University, Richmond, VA, US
AN  - 2020-12978-001
AU  - Khurana,
AU  - Sonia
AU  - Kane,
AU  - Audrey
AU  - E.
AU  - Brown,
AU  - Shaaron
AU  - E.
AU  - Tarver,
AU  - Talicia
AU  - Dusing,
AU  - Stacey
AU  - C.
DA  - Jun
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/dmcn.14485
DP  - Ovid Technologies
KW  - neonatal therapy, infant development, cognitive devleopment, behavioral development
KW  - *Cognitive Development
KW  - *Infant Development
KW  - *Medical Treatment (General)
KW  - *Motor Development
KW  - *Premature Birth
KW  - Early Childhood Development
KW  - Neonatal Intensive Care
KW  - Health &amp; Mental Health Services [3370]
KW  - Human Childhood (birth-12 yrs) Neonatal (birth-1 mo) Infancy (2-23 mo)
L1  - internal-pdf://2662889898/Khurana-2020.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2020
SP  - 684-692
T2  - Developmental Medicine &amp; Child Neurology
TI  - Effect of neonatal therapy on the motor, cognitive, and behavioral development of infants born preterm: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2020-12978-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1111%2Fdmcn.14485&amp;issn=0012-1622&amp;isbn=&amp;volume=62&amp;issue=6&amp;spage=684&amp;pages=684-692&amp;date=2020&amp;title=Developmental+Medicine+%26+Child+Neurology&amp;atitle=Effect+of+neonatal+therapy+on+the+motor%2C+cognitive%2C+and+behavioral+development+of+infants+born+preterm%3A+A+systematic+review.&amp;aulast=Khurana&amp;pid=%3Cauthor%3EKhurana%2C+Sonia%3C%2Fauthor%3E%3CAN%3E2020-12978-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/dmcn.14485
VL  - 62
ER  -
TY  - JOUR
AB  - Feeding preterm infants with mother&#039;s own milk is associated with a reduction in postnatal complications and an improved neurocognitive outcome. Therefore, the bioactive factor composition of human milk has been used as a tool for the development of nutritional supplements with a potential prophylactic or therapeutic effect. 

The aim of this systematic review was to provide an overview on bioactive factors which have been studied as supplement to enteral nutrition in randomized controlled trials, and to provide an overview of ongoing trials. MEDLINE, EMBASE, CENTRAL, and clinical trial registers were searched. Studies on the antimicrobial protein lactoferrin were excluded as these were summarized very recently in three separate systematic reviews. Studies on vitamins D, K and iron were also excluded as they are already incorporated in most international guidelines. 

We identified 17 different bioactive factors, which were investigated in 26 studies. Despite the encouraging potential effects of several bioactive factors, more high-quality studies with a sufficient number of preterm infants are required before a certain factor may be implemented into clinical practice. Three large trials (n &gt; 500) that investigate the effects of either enteral insulin or vitamin A are currently ongoing and could provide more definite answers on these specific supplements.
AD  - Mank, Elise. Department of Pediatrics-Neonatology, Emma Children&#039;s Hospital, Amsterdam UMC, University of Amsterdam, Vrije Universiteit, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.Naninck, Eva F G. Department of Pediatrics-Neonatology, Emma Children&#039;s Hospital, Amsterdam UMC, University of Amsterdam, Vrije Universiteit, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.Naninck, Eva F G. Swammerdam Institute for Life Sciences-Center for Neuroscience, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.Limpens, Jacqueline. Medical Library, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.van Toledo, Letty. Department of Pediatrics-Neonatology, Emma Children&#039;s Hospital, Amsterdam UMC, University of Amsterdam, Vrije Universiteit, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.van Goudoever, Johannes B. Department of Pediatrics-Neonatology, Emma Children&#039;s Hospital, Amsterdam UMC, University of Amsterdam, Vrije Universiteit, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.van den Akker, Chris H P. Department of Pediatrics-Neonatology, Emma Children&#039;s Hospital, Amsterdam UMC, University of Amsterdam, Vrije Universiteit, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
AN  - 32987621
AU  - Mank,
AU  - E.
AU  - Naninck,
AU  - E.
AU  - F.
AU  - G.
AU  - Limpens,
AU  - J.
AU  - van
AU  - Toledo,
AU  - L.
AU  - van
AU  - Goudoever,
AU  - J.
AU  - B.
AU  - van
AU  - den
AU  - Akker,
AU  - C.
AU  - H.
AU  - P.
DA  - Sep 24
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/nu12102916
DP  - Ovid Technologies
J2  - Nutrients
KW  - Child Development/de [Drug Effects]
KW  - Databases, Factual
KW  - *Dietary Supplements
KW  - Enteral Nutrition
KW  - Humans
KW  - Infant
KW  - *Infant Nutritional Physiological Phenomena
KW  - *Infant, Premature/gd [Growth &amp; Development]
KW  - Milk, Human
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
L1  - internal-pdf://0182602038/Mank-2020.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Using Smart Source ParsingSepMank, EliseNaninck, Eva F GLimpens, Jacquelinevan Toledo, Lettyvan Goudoever, Johannes Bvan den Akker, Chris H PE2916
PY  - 2020
SP  - 24
T2  - Nutrients
TI  - Enteral Bioactive Factor Supplementation in Preterm Infants: A Systematic Review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=32987621
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32987621&amp;id=doi:10.3390%2Fnu12102916&amp;issn=2072-6643&amp;isbn=&amp;volume=12&amp;issue=10&amp;spage=&amp;pages=&amp;date=2020&amp;title=Nutrients&amp;atitle=Enteral+Bioactive+Factor+Supplementation+in+Preterm+Infants%3A+A+Systematic+Review.&amp;aulast=Mank&amp;pid=%3Cauthor%3EMank+E%3C%2Fauthor%3E%3CAN%3E32987621%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://res.mdpi.com/d_attachment/nutrients/nutrients-12-02916/article_deploy/nutrients-12-02916-v3.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **Objective:** 
Foster family care is associated with adverse short- and long-term consequences for the child. A systematic review was conducted on interventions for foster children and foster careers. 

**Method:** 
A comprehensive search process was used to find eligible interventions evaluated in randomized controlled trials or quasi-experimental studies. The quality of studies was assessed with GRADE, and effects were synthesized using meta-analytic methods. 

**Results:** 
In all, 28 publications of 18 interventions, including 5,357 children, were identified. Only three specific interventions had sufficient confidence of evidence. No study had examined tools for foster parent selection nor had evaluated preservice programs related to outcomes. 

**Discussion:** 
These analyses provide new insights and hope into the field of systematic interventions in foster care. The overall results indicate that it is possible to improve eight outcomes but cannot point out which programs are superior. Ethically, social care organizations should systematically collect knowledge about effects and side effects.
AD  - [Bergstrom, Martin] Lund Univ, Sch Social Work, Box 23, S-22100 Lund, Sweden. [Cederblad, Marianne] Lund Univ, Dept Child &amp; Adolescent Psychiat, Lund, Sweden. [Hakansson, Kickan; Jonsson, Ann Kristine; Ostlund, Pernilla; Sundell, Knut] Swedish Agcy Hlth Technol Assessment &amp; Assessment, Stockholm, Sweden. [Munthe, Christian] Univ Gothenburg, Dept Philosophy Linguist &amp; Theory Sci, Gothenburg, Sweden. [Vinnerljung, Bo] Stockholm Univ, Dept Social Work, Stockholm, Sweden. [Vinnerljung, Bo] Karolinska Inst, Dept Med, Div Clin Epidemiol, Solna, Sweden. [Wirtberg, Ingegerd] Lund Univ, Dept Psychol, Lund, Sweden. [Ostlund, Pernilla] Malmo Univ, Fac Odontol, Hlth Technol Assessment Odontol, Malmo, Sweden. [Sundell, Knut] Karolinska Inst, Med Management Ctr, Dept Learning Informat Management &amp; Eth, Solna, Sweden.Bergstrom, M (reprint author), Lund Univ, Sch Social Work, Box 23, S-22100 Lund, Sweden.martin.bergstrom@soch.lu.se
AN  - WOS:000501618500001
AU  - Bergstrom,
AU  - M.
AU  - Cederblad,
AU  - M.
AU  - Hakansson,
AU  - K.
AU  - Jonsson,
AU  - A.
AU  - K.
AU  - Munthe,
AU  - C.
AU  - Vinnerljung,
AU  - B.
AU  - Wirtberg,
AU  - I.
AU  - Ostlund,
AU  - P.
AU  - Sundell,
AU  - K.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/1049731519832101
J2  - Res. Soc. Work. Pract.
KW  - foster care
KW  - field of practice
KW  - systematic review
KW  - literature review
KW  - adolescents
KW  - population
KW  - children
KW  - prevention
KW  - ethics
KW  - foster parent
KW  - selection
KW  - preservice training
KW  - skills group program
KW  - of-home care
KW  - mental-health
KW  - permanency outcomes
KW  - behavior problems
KW  - child protection
KW  - young-people
KW  - follow-up
KW  - placement
KW  - youth
KW  - Social Work
L1  - internal-pdf://0765236252/Bergstrom-2020-Interventions in Foster Family.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: JU3ZZTimes Cited: 2Cited Reference Count: 73Bergstrom, Martin Cederblad, Marianne Hakansson, Kickan Jonsson, Ann Kristine Munthe, Christian Vinnerljung, Bo Wirtberg, Ingegerd Ostlund, Pernilla Sundell, KnutBergstrom, Martin/0000-0001-7469-796125Sage publications incThousand oaks1552-7581
PY  - 2020
SP  - 3-18
T2  - Research on Social Work Practice
TI  - Interventions in Foster Family Care: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000501618500001
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1049731519832101
VL  - 30
ER  -
TY  - JOUR
AB  - Animal-assisted therapy (AAT) has been suggested to increase prosocial behavior in children diagnosed with Autism Spectrum Disorder (ASD). Out of all the animals used in AAT, dogs have been found to be the most utilized and accessible. This systematic review examines the current state of literature on canine-assisted therapy (CAT) for children with ASD based on peer-reviewed articles. Five studies met inclusion and exclusion criteria. All articles found that presence of a therapy dog was correlated with increased frequency and duration of social behavior both throughout treatment and, in the case of one study, at follow-up. However, methodological limitations such as small sample sizes and sub-optimal analytic procedures suggest that existing studies might not accurately reflect the true nature of the relationship between CAT and social behavior. Therefore, further exploration of this area of research using methodologically strong studies is warranted and necessary. Recommendations for future research are included.
AN  - WOS:000533787800006
AU  - Hardy,
AU  - K.
AU  - K.
AU  - Weston,
AU  - R.
AU  - N.
DA  - May
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40489-019-00188-5
L1  - internal-pdf://0757820331/Hardy-2020.pdf
N1  - Hardy, Kristin K. Weston, Robyn N.2195-7185
PY  - 2020
SP  - 197-204
T2  - Review Journal of Autism and Developmental Disorders
TI  - Canine-Assisted Therapy for Children with Autism Spectrum Disorder: a Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000533787800006
UR  - https://link.springer.com/article/10.1007%2Fs40489-019-00188-5
UR  - https://link.springer.com/content/pdf/10.1007/s40489-019-00188-5.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - **Background:** 
Adolescence is a period of brain plasticity that is affected by social and affective stimuli. Adaptive neurodevelopmental changes in the context of complex social situations may precipitate or exacerbate cognitive biases (i.e., attention and/or interpretation biases) and predispose at-risk individuals to symptoms of social anxiety. 

**Method(s):** 
This systematic review followed the PRISMA guidelines. Nine adolescent studies were examined including 3 studies using Cognitive Bias Modification Training (CBMT) to target attention biases (CBMT-A), 3 studies using CBMT to target interpretation biases (CBMT-I), and 3 aimed at reducing both attention and interpretation biases. 

**Result(s):** 
The studies of CBMT-A alone did not find significant effects on cognitive and clinical outcomes. However, studies of CBMT-I alone showed some improvement in interpretation bias. The combination of CBMT-A and CBMT-I appeared promising in reducing both attentionl and interpretation biases. 

**Limitation(s):** 
The paucity of studies and the heterogeneity across studies (e.g., format of CBMT, assessment measures) limit the calculation of overall effect sizes and the examination of predictors, moderators, and mediators of outcome. 

**Conclusion(s):** 
Technology-driven interventions such as CBMT have the potential to extend treatments outside the clinic setting and to augment current therapies for social anxiety. Further research is needed to develop CBMT procedures that optimize learning in group and real-world settings and to identify predictors of treatment response. Understanding the neural correlates of response to CBMT may help identify future targets for intervention. Copyright &copy; 2019
AD  - (Biagianti) Department of R&amp;D, Posit Science Corporation, San Francisco, CA, United States (Biagianti, Brambilla) Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy (Conelea, Bernstein) Department of Psychiatry, University of Minnesota, Minneapolis, MN, United States (Brambilla) Department of Neurosciences and Mental Health, Fondazione IRCCS Ca&#039; Granda Ospedale Maggiore Policlinico, Milan, ItalyB. Biagianti, Department of R&amp;D, Posit Science Corporation, San Francisco, CA, United States. E-mail: bruno.biagianti@positscience.com
AN  - 2004236706
AU  - Biagianti,
AU  - B.
AU  - Conelea,
AU  - C.
AU  - Brambilla,
AU  - P.
AU  - Bernstein,
AU  - G.
DA  - 1 March
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2019.12.002
DP  - Ovid Technologies
KW  - adolescent
KW  - anxiety
KW  - attentional bias
KW  - calculation
KW  - clinical outcome
KW  - effect size
KW  - female
KW  - human
KW  - interpretation bias
KW  - learning
KW  - male
KW  - outcome assessment
KW  - Preferred Reporting Items for Systematic Reviews and Meta Analyses
KW  - review
KW  - systematic review
KW  - treatment response
L1  - internal-pdf://1929680509/Biagianti-2020-A systematic review of treatmen.pdf
LA  - English
M3  - Review
PY  - 2020
SP  - 543-551
T2  - Journal of Affective Disorders
TI  - A systematic review of treatments targeting cognitive biases in socially anxious adolescents: Special Section on &quot;Translational and Neuroscience Studies in Affective Disorders&quot; Section Editor, Maria Nobile MD, PhD
UR  - http://www.elsevier.com/locate/jad
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2004236706
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:32056778&amp;id=doi:10.1016%2Fj.jad.2019.12.002&amp;issn=0165-0327&amp;isbn=&amp;volume=264&amp;issue=&amp;spage=543&amp;pages=543-551&amp;date=2020&amp;title=Journal+of+Affective+Disorders&amp;atitle=A+systematic+review+of+treatments+targeting+cognitive+biases+in+socially+anxious+adolescents%3A+Special+Section+on+%22Translational+and+Neuroscience+Studies+in+Affective+Disorders%22+Section+Editor%2C+Maria+Nobile+MD%2C+PhD&amp;aulast=Biagianti&amp;pid=%3Cauthor%3EBiagianti+B.%3C%2Fauthor%3E%3CAN%3E2004236706%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/271035/1-s2.0-S0165032719X00191/1-s2.0-S0165032719326886/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjECgaCXVzLWVhc3QtMSJHMEUCIFNKnsyFeRar4S2mpuM2fvx2mH1iEEyH837IAKimLFPxAiEA0%2FVWZ4AuGaCDTrYk69X6dxU4Brk9yEWU4GNqODGQjj4qtAMIERACGgwwNTkwMDM1NDY4NjUiDJdPLOnKvrbBJOYFtCqRA9k2jte5vYeEk2B0MFv3H%2BR14dyT3f%2Fx0uWJBaa7OeCdC0uaz0BbRm7xgIZroahwmdOtcI%2F%2Bk2RdwoaFKCuVT6lfQhv2UHCLOHK%2BtfGlZICcLOSlenz54if%2F3%2F2AGMSe9su8NHbVv8JXW6DkkcSMyZqyx%2BvhIgA2USG9MCJcH98bXvY3zumfOo2abKszleRPPDkqDVPYrGJh2hLM%2B2GBDUgmPSznmPA%2F1mrkb8MU68Sb0NV0Blobl1fACnd%2FWVpxCYm9v1jRUa0gZ8%2BiUlzlnMnozkz8OoK5ChPQudATCIFnsJcb9Zv4nq%2FlWobPUPYcwbgqNzX1zvcMVcuMklKftJk%2FqK%2BLw%2Bpc5W0dUAjCsqlwExVfz605N09XQsmsk15CVpfa51VwJvAc2f6KGUuLmP2W5mBCw7ZobpNjQ2Ne7K2k2JEiPUbQk7qHY1%2Fpt1eErmh64TJSrF6uno6PyHWEFWhQjhZFwCJoUmFEs8ocyy2DnoEYWpPddj16MumFSlXPTUq8%2FUwsWP2LWm1CQX6zEtqhMOGjovMFOusBuwKv8CkENqk4t7zdDYrJ1M5FffuF5vVxtomqzMUoF%2BLFQDHuyp8TVEWHGeK0Ps0cp%2Bb5WNN%2BqB5NfOlC1unnhKRoD60cLxcmFI6L7BTAaWrSwUql7BGQF2cEm3kyss7bNXuzOMkia5uVC2koktuAxMYjAaznqALw8H9rySeotwDAmSsI0Z9A5wg9t8Rsb0b3jp4tO5vaeHViBQnspBJEw4MhiCaD7G6mlKSfhEB8fsFgGI%2B%2BbjyUks9LuS4RQMKUS%2BTMPhNd9WvXHuj%2BVAYEyrDyQSNkMhyDpR5KEkIU%2BCz%2BoW3ypXDkDcfJnA%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200311T073425Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYYECGES6F%2F20200311%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=c6647e40420d61702d4296eb08b0edb099df1826ca3219bd62c2595c67be7dec&amp;hash=8d05999029285b53e765d5a6b4dbe50ccad4017a540e6ae6e416d53643d3b6c9&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0165032719326886&amp;tid=spdf-42d237c1-ae92-47d9-b382-99e22b3fa01d&amp;sid=8321b27350baf84ef38be4a5b7ace7a282e9gxrqb&amp;type=client
VL  - 264
ER  -
TY  - JOUR
AB  - This review investigated virtual reality and augmented reality (VR/AR) communication interventions for children, adolescents, and adults with communication disability and neurodevelopmental disorders, as well the feasibility of these technologies. A search of five scientific databases yielded 5385 potentially relevant records of which 69 met inclusion criteria. Studies reported on a wide range of VR/AR devices, platforms, and applications for people with autism spectrum disorder, communication disorders, and intellectual disability. Some VR/AR systems hosted effective communication interventions; however, participant outcomes varied across the included studies. Most participants with neurodevelopmental disorders and their supporters were able to access learning experiences using VR/AR and few adverse effects were reported. Directions for future research are discussed.
AN  - WOS:000659411000001
AU  - Bailey,
AU  - B.
AU  - Bryant,
AU  - L.
AU  - Hemsley,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40489-020-00230-x
L1  - internal-pdf://2864598880/Bailey-Virtual Reality and Augmented Reality f.pdf
PY  - 2020
SP  - 24
T2  - Review Journal of Autism and Developmental Disorders
TI  - Virtual Reality and Augmented Reality for Children, Adolescents, and Adults with Communication Disability and Neurodevelopmental Disorders: a Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000659411000001
UR  - https://link.springer.com/content/pdf/10.1007/s40489-020-00230-x.pdf
ER  -
TY  - JOUR
AB  - This study explored the effectiveness of behavioral intervention technologies (BITs) and face-to-face cognitive behavioral therapy (F2FCBT). Systematic review methods and meta-analysis techniques were used to analyze nineteen randomized controlled trials comparing face-to-face cognitive behavioral therapy (F2FCBT), or BITS, vs. a wait list control or a non-evidence-based control. A random-effects model was used, and effect sizes were calculated using Hedges&#039; g to determine the effectiveness of treatment from pre- to post-test and pre to follow-up. Subgroup comparisons were run for age and type of control group. Results of the analysis show that both interventions were effective for reducing childhood depression from pre-test to post-test, (F2FCBT g = - 0.36 and BITs g = - 0.34) and were not significantly different from one another (p = .90). At a 6-month follow-up, F2FCBT interventions were not significantly better than controls, and BITs were shown to be significantly better than controls. F2FCBT and BITs did not differ significantly from one another (p = 0.92). A subgroup analysis revealed that interventions targeted at adolescents were more effective (g = -0.51) than interventions targeting mixed ages. It was found that BITs were effective as a treatment of child and adolescent depression and were as effective in treating depression as F2FCBT, the gold standard treatment. Current evidence provides promising results that support the utilization of BITs as a treatment for depression in children and adolescents. (PsycInfo Database Record (c) 2022 APA, all rights reserved)
AN  - 2020-81064-005
AU  - Higinbotham,
AU  - M.
AU  - Emmert-Aronson,
AU  - B.
AU  - Bunge,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s41347-020-00139-6
L1  - internal-pdf://0612477594/A meta-analysis of the effectiveness of b-2020.pdf
PY  - 2020
SP  - 324-335
T2  - Journal of Technology in Behavioral Science
TI  - A meta-analysis of the effectiveness of behavioral intervention technologies and face-to-face cognitive behavioral therapy for youth with depression
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc18&amp;AN=2020-81064-005
UR  - https://link.springer.com/content/pdf/10.1007/s41347-020-00139-6.pdf
VL  - 5
ER  -
TY  - JOUR
AB  - **Background:** 
All children benefit from intentional interactions and instruction to become socially and emotionally competent. Over the past 30 years, evidence-based intervention tactics and strategies have been integrated to establish comprehensive, multitiered, or hierarchical systems of support frameworks to guide social-emotional interventions for young children. 

**Objectives:** 
To review systematically the efficacy of classroom-wide social-emotional interventions for improving the social, emotional, and behavioral outcomes of preschool children and to use meta-analytic techniques to identify critical study characteristics associated with obtained effect sizes. 

**Method:** 
Four electronic databases (i.e., Academic Search Premier, Educational Resource Information Center, PsycINFO, and Education Full Text) were systematically searched in December 2015 and updated in January 2018. &quot;Snowball methods&quot; were used to locate additional relevant studies. Effect size estimates were pooled using random-effects meta-analyses for three child outcomes, and moderator analyses were conducted. 

**Results:** 
Thirty-nine studies involving 10,646 child participants met the inclusion criteria and were included in this systematic review, with 33 studies included in the meta-analyses. Random-effects meta-analyses showed improvements in social competence (g= 0.42, 95% confidence interval [CI] = [0.28, 0.56]) and emotional competence (g= 0.33, 95% CI = [0.10, 0.56]), and decreases in challenging behavior (g= -0.31, 95% CI = [-0.43, -0.19]). For social competence and challenging behavior, moderator analyses suggested interventions with a family component had statistically significant and larger effect sizes than those without a family component. Studies in which classroom teachers served as the intervention agent produced statistically significant but smaller effect sizes than when researchers or others implemented the intervention for challenging behavior. 

**Conclusion:** 
This systematic review and meta-analysis support using comprehensive social-emotional interventions for all children in a preschool classroom to improve their social-emotional competence and reduce challenging behavior.
AN  - WOS:000570652600001
AU  - Luo,
AU  - L.
AU  - Reichow,
AU  - B.
AU  - Snyder,
AU  - P.
AU  - Harrington,
AU  - J.
AU  - Polignano,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/0271121420935579
L1  - internal-pdf://1951104303/Luo.pdf
N1  - Luo, Li Reichow, Brian Snyder, Patricia Harrington, Jennifer Polignano, Joy1538-4845
PY  - 2020
T2  - Topics in Early Childhood Special Education
TI  - Systematic Review and Meta-Analysis of Classroom-Wide Social-Emotional Interventions for Preschool Children
UR  - &lt;Go to ISI&gt;://WOS:000570652600001
UR  - https://journals.sagepub.com/doi/10.1177/0271121420935579
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0271121420935579
ER  -
TY  - JOUR
AB  - This paper aimed to discuss the intervention effects of physical activities on children and adolescents with autism with a meta-analysis so as to serve as a reference to further relevant research on the same topic. As for research methods, by searching in CNKI (China National Knowledge Infrastructure), WanFang data, VIP Database for Chinese Technical Periodicals, PubMed, Scopus, Web of Science, and other databases, this study collected randomized controlled trials (RCTs) on the intervention of physical activities on children and adolescents with autism and used Review Manager 5.3 software to process and analyze the outcome indicators of the literature. As for the result, a total of 12 papers and 492 research targets were selected. The results of the meta-analysis show that physical activity had a significant positive impact on social interaction ability, communication ability, motor skills, and autism degree of autistic children as well as the social skills and communication skills of autistic adolescents. On the other hand, physical activity had no significant effect on the stereotyped behavior of autistic children and adolescents. In conclusion, physical activity intervention is beneficial to children and adolescents with autism, and continuous physical activity intervention can produce greater intervention effect.
AD  - Huang, Jinfeng. School of Physical Education, South China Normal University, Guangzhou 510631, China.Du, Chunjie. College of Vocational and Technical Education, South China Normal University, Nanhai 528000, China.Liu, Jianjin. Department of Physical Education, Guangzhou College of Commerce, Guangzhou 511363, China.Tan, Guangxin. School of Physical Education, South China Normal University, Guangzhou 510631, China.
AN  - 32192008
AU  - Huang,
AU  - J.
AU  - Du,
AU  - C.
AU  - Liu,
AU  - J.
AU  - Tan,
AU  - G.
DA  - Mar 17
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/ijerph17061950
DP  - Ovid Technologies
J2  - Int J Environ Res Public Health
L1  - internal-pdf://1047205624/Huang-2020-Meta-Analysis on Intervention Effec.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingMarHuang, JinfengDu, ChunjieLiu, JianjinTan, GuangxinE1950
PY  - 2020
SP  - 17
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - Meta-Analysis on Intervention Effects of Physical Activities on Children and Adolescents with Autism
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32192008
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32192008&amp;id=doi:10.3390%2Fijerph17061950&amp;issn=1660-4601&amp;isbn=&amp;volume=17&amp;issue=6&amp;spage=&amp;pages=&amp;date=2020&amp;title=International+Journal+of+Environmental+Research+%26+Public+Health+%5BElectronic+Resource%5D&amp;atitle=Meta-Analysis+on+Intervention+Effects+of+Physical+Activities+on+Children+and+Adolescents+with+Autism.&amp;aulast=Huang&amp;pid=%3Cauthor%3EHuang+J%3C%2Fauthor%3E%3CAN%3E32192008%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://res.mdpi.com/d_attachment/ijerph/ijerph-17-01950/article_deploy/ijerph-17-01950.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - INTRODUCTION: Autism spectrum disorder (ASD), a heterogeneous neurodevelopmental disorder, impacts social experience and functioning throughout the lifespan. Although the postnatal phase of neuroplasticity has been a focus for early interventions in ASD, a second critical period in adolescence has emerged as a promising target for experience-dependent remediation. Interventions addressing the multidimensional construct of social cognition have also shown potential as a therapeutic approach. Yet, to date, evidence-based social cognitive interventions (SCIs) designed for adolescents with ASD are still lacking. In this review, we aim to survey and synthesize the extant literature on SCIs for adolescents with ASD in order to inform next steps for treatment research.

METHODS: Using the PRISMA guidelines, we limited our queries to peer-reviewed, English-language journal articles describing SCI trials for adolescents with ASD using a randomized controlled design.

RESULTS: Eighteen articles in total met our inclusion/exclusion criteria. We present and discuss these trials using the non-exclusive categories of group-based social skills interventions, experiential-based interventions, and computer-assisted interventions.

LIMITATIONS: To ensure a focus on adolescence, we excluded trials with teen-age participants if mean subject age was not between 12-18 years. Also, given the variability across studies in outcome measures, study designs, samples, and effect sizes, findings were incommensurable.

CONCLUSIONS: Several reviewed SCIs reported post-treatment improvements in varied domains but findings were inconsistent. Further investigations of existing and novel interventions are warranted; attention to assessing and improving long-term skill transfer is essential. Technology-assisted augmentations may improve treatment efficacy and ecological validity of therapeutic gains.
AD  - Tseng, Angela. Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, USA.Biagianti, Bruno. Department of R&amp;D, Posit Science Corporation, San Francisco, CA, USA; Department of Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. Electronic address: bruno.biagianti@gmail.com.Francis, Sunday M. Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, USA.Conelea, Christine A. Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, USA.Jacob, Suma. Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, USA.
AN  - 32469804
AU  - Tseng,
AU  - A.
AU  - Biagianti,
AU  - B.
AU  - Francis,
AU  - S.
AU  - M.
AU  - Conelea,
AU  - C.
AU  - A.
AU  - Jacob,
AU  - S.
DA  - May 25
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2020.05.134
DP  - Ovid Technologies
J2  - J Affect Disord
L1  - internal-pdf://1452126166/Tseng-2020-Social Cognitive Interventions for.pdf
LA  - English
M3  - Review
N1  - Tseng, AngelaBiagianti, BrunoFrancis, Sunday MConelea, Christine AJacob, SumaS0165-0327(20)31360-4
PY  - 2020
SP  - 199-204
T2  - Journal of Affective Disorders
TI  - Social Cognitive Interventions for Adolescents with Autism Spectrum Disorders: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32469804
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32469804&amp;id=doi:10.1016%2Fj.jad.2020.05.134&amp;issn=0165-0327&amp;isbn=&amp;volume=274&amp;issue=&amp;spage=199&amp;pages=199-204&amp;date=2020&amp;title=Journal+of+Affective+Disorders&amp;atitle=Social+Cognitive+Interventions+for+Adolescents+with+Autism+Spectrum+Disorders%3A+A+Systematic+Review.&amp;aulast=Tseng&amp;pid=%3Cauthor%3ETseng+A%3C%2Fauthor%3E%3CAN%3E32469804%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/271035/1-s2.0-S0165032720X00115/1-s2.0-S0165032720313604/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEIT%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQC0jr2Vcn9Ss%2BYULv7F2oEJROYTIqZnFG6l0CvtBRZsAQIhANDf7X6HFMWVOYmvgBysPVg9OXh9JjqVgAkFks70TlnDKrQDCCwQAxoMMDU5MDAzNTQ2ODY1Igz2h6IwAq9tPnJdr5gqkQMFCvMSDeB8ux9Oejxq6Qb7RYGQfdyIAokR%2FPUMjhT6wCZBHQKAPtHWEV3s4TQvf8emN71fZfzas3ZQ0iVbf9yIoV17moL0Di8XHUFYHevi63BxEm9vPMeNPDgGQmzWEARhQ8v%2FJuIS2%2FUwZ%2BwQkwSEtFBIWU%2BzaG1TJkF9nEwLQt7unaKXSas27dXU9t4NkLufh1RIy0bava6u8UgaOM2V8zWrXx4Lhk3qrhgbc9nvfQrm1CQLGycpA3VStoivh%2FT0604Vk1WNtKLDMLLTfS0LYcsGqPeAVOGH98ADgzxACu4olomdX%2FG011en5x4mjncWl0afIOPmFgNw1utk%2Bdh8dxz04d1keajOVJt4zE5d0s6OsxdOepxehovHShlyIX0hTd5qnHFwgji55uh%2FKWuT8%2BrsokHdC1EIkgOQywcVw%2FTsnJGji6zuv6vGLa0KoDk4JdXh%2BUUHriErc%2B9q9PY2AVN8mCWxPyy41fE3X%2BMuc9VtdgvKdZz11x%2BUtPrguJKzVD4%2FmrZUH%2FonHcg5Z3yjJDCcnqH4BTrqAVcDcToFjehE7V3QrPpnc7zXXqfx0Y6E5BeyH1g0K35DdLMrqcXgvxUWgz2Y5U%2FuYwlScU6UvtmIzQDlLzqwdojdc5MsUteGs6NAUGqvkWDMQ%2BhTIK0e7IgP3xB8b41y8da29HV4FwV4KQkUH7Maney%2BWGUs3pj5UkpdbWvL4gav%2FRMUtTiLl9e7lpLOJ9MHa0ri6rRwhx2fe8b8WstLH8GVEWvg6MWXK27tzx5jV03166efqvneR0NnOZcbM1P8AF%2B4dwWbV2BL9AlzLwVtPCyIodT6IGdvutyIGfA9rBk%2F%2BUd5PuNZ%2BcwhoA%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200710T122700Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY5LY7CY76%2F20200710%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=2a52128cb7ff746c868ef125b27a0185df6bd75f879be3f15a6218791c64add5&amp;hash=49b54311a39a681a07cfa9f2b62867971cb19326fdaec6a625a3383db4db90eb&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0165032720313604&amp;tid=spdf-af4214c3-4a4d-43f8-aa5a-7297dc5d2be9&amp;sid=7db55e4a1e53c345f64a15b643c885f9597cgxrqb&amp;type=client
VL  - 274
ER  -
TY  - JOUR
AB  - **Background:**
 Anxiety and depressive disorders are prevalent in adolescents and young adults. However, most young people with mental health problems do not receive treatment. Computerized cognitive behavior therapy (cCBT) may provide an accessible alternative to face-to-face treatment, but the evidence base in young people is limited. 

**Objective(s):** 
The objective was to perform an up-to-date comprehensive systematic review and meta-analysis of the effectiveness of cCBT in treating anxiety and depression in adolescents and young adults compared with active treatment and passive controls. We aimed to examine posttreatment and follow-up effects and explore the moderators of treatment effects. 

**Method(s):** 
We conducted systematic searches in the following six electronic databases: PubMed, EMBASE, PsycINFO, CINAHL, Web of Science, and Cochrane Central Register of Controlled Trials. We included randomized controlled trials comparing cCBT with any control group in adolescents or young adults (age 12-25 years) with anxiety or depressive symptoms. The quality of included studies was assessed using the Cochrane risk-of-bias tool for randomized trials, version 2.0. Overall quality of evidence for each outcome was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Posttreatment means and SDs were compared between intervention and control groups, and pooled effect sizes (Hedges g) were calculated. Random-effects meta-analyses were conducted using Comprehensive Meta-Analysis software. Subgroup analyses and meta-regression analyses were conducted to explore whether age, guidance level, and adherence rate were associated with treatment outcome. 

**Result(s):** 
The search identified 7670 papers, of which 24 studies met the inclusion criteria. Most included studies (22/24) had a high risk of bias owing to self-report measures and/or inappropriate handling of missing data. Compared with passive controls, cCBT yielded small to medium posttreatment pooled effect sizes regarding depressive symptoms (g=0.51, 95% CI 0.30-0.72, number needed to treat [NNT]=3.55) and anxiety symptoms (g=0.44, 95% CI 0.23-0.65, NNT=4.10). cCBT yielded effects similar to those of active treatment controls regarding anxiety symptoms (g=0.04, 95% CI -0.23 to 0.31). For depressive symptoms, the nonsignificant pooled effect size favored active treatment controls (g=-0.70, 95% CI -1.51 to 0.11, P=.09), but heterogeneity was very high (I&lt;sup&gt;2&lt;/sup&gt;=90.63%). No moderators of treatment effects were identified. At long-term follow-up, cCBT yielded a small pooled effect size regarding depressive symptoms compared with passive controls (g=0.27, 95% CI 0.09-0.45, NNT=6.58). No other follow-up effects were found; however, power was limited owing to the small number of studies. 

**Conclusion(s):** 
cCBT is beneficial for reducing posttreatment anxiety and depressive symptoms in adolescents and young adults compared with passive controls. Compared with active treatment controls, cCBT yielded similar effects regarding anxiety symptoms. Regarding depressive symptoms, however, the results remain unclear. More high-quality research involving active controls and long-term follow-up assessments is needed in this population. 
Copyright &copy; Carolien Christ, Maria JE Schouten, Matthijs Blankers, Digna JF van Schaik, Aartjan TF Beekman, Marike A Wisman, Yvonne AJ Stikkelbroek, Jack JM Dekker. Originally published in the Journal of Medical Internet Research (http://www.jmir.org),25.09.2020. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included.
AD  - (Christ, van Schaik, Beekman) Department of Psychiatry, GGZ inGeest, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands (Christ, Schouten, Blankers, Dekker) Department of Research, Arkin Mental Health Care, Amsterdam, Netherlands (Christ, van Schaik, Beekman) Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands (Blankers) Trimbos institute, Netherlands Institute of Mental Health and Addiction, Utrecht, Netherlands (Wisman) Department of Youth and Family, Arkin Mental Health Care, Amsterdam, Netherlands (Stikkelbroek) Department of Child and Adolescent Studies, Universiteit Utrecht, Utrecht, Netherlands (Stikkelbroek) Depression Expert Center for Youth, Mental Health Care Oost-Brabant, Boekel, Netherlands (Dekker) Department of Clinical Psychology, Vrije Universiteit Amsterdam, Amsterdam, NetherlandsC. Christ, Department of Psychiatry GGZ inGeest Amsterdam UMC, Vrije Universiteit Amsterdam, Oldenaller 1, Amsterdam 1081 HJ, Netherlands. E-mail: c.christ@ggzingeest.nl
AN  - 2008344520
AU  - Christ,
AU  - C.
AU  - Schouten,
AU  - M.
AU  - J.
AU  - E.
AU  - Blankers,
AU  - M.
AU  - van
AU  - Schaik,
AU  - D.
AU  - J.
AU  - F.
AU  - Beekman,
AU  - A.
AU  - T.
AU  - F.
AU  - Wisman,
AU  - M.
AU  - A.
AU  - Stikkelbroek,
AU  - Y.
AU  - A.
AU  - J.
AU  - Dekker,
AU  - J.
AU  - J.
AU  - M.
DA  - okt 23
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/17831
DP  - Ovid Technologies
KW  - Anxiety
KW  - Cognitive behavior therapy
KW  - Depression
KW  - Internet
KW  - Meta-analysis
KW  - Youth
KW  - adolescent
KW  - adolescent depression
KW  - adult
KW  - child
KW  - Cinahl
KW  - Cochrane Library
KW  - cognitive behavioral therapy
KW  - controlled study
KW  - effect size
KW  - Embase
KW  - female
KW  - follow up
KW  - human
KW  - male
KW  - Medline
KW  - meta analysis
KW  - PsycINFO
KW  - randomized controlled trial (topic)
KW  - review
KW  - risk assessment
KW  - school child
KW  - self report
KW  - software
KW  - systematic review
KW  - Web of Science
KW  - young adult
L1  - internal-pdf://2307104384/Christ-2020.pdf
LA  - English
M3  - Review
PY  - 2020
T2  - Journal of Medical Internet Research
TI  - Internet and computer-based cognitive behavioral therapy for anxiety and depression in adolescents and young adults: Systematic review and meta-analysis
UR  - https://www.jmir.org/2020/9/e17831
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2008344520
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:32673212&amp;id=doi:10.2196%2F17831&amp;issn=1438-8871&amp;isbn=&amp;volume=22&amp;issue=9&amp;spage=e17831&amp;pages=&amp;date=2020&amp;title=Journal+of+Medical+Internet+Research&amp;atitle=Internet+and+computer-based+cognitive+behavioral+therapy+for+anxiety+and+depression+in+adolescents+and+young+adults%3A+Systematic+review+and+meta-analysis&amp;aulast=Christ&amp;pid=%3Cauthor%3EChrist+C.%3C%2Fauthor%3E%3CAN%3E2008344520%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 22 (9) (no pagination)
ER  -
TY  - JOUR
AB  - BACKGROUND: Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) could provide treatment alternatives to stimulant medication for attention-deficit/hyperactivity disorder (ADHD), given some evidence for improvements in cognition and clinical symptoms. However, despite a lack of solid evidence for their use, rTMS and tDCS are already offered clinically and commercially in ADHD. This systematic review and meta-analysis aimed to critically appraise rTMS and tDCS studies in ADHD to inform good research and clinical practice.

METHODS: A systematic search (up to February 2019) identified 18 studies (rTMS 4, tDCS 14; 311 children and adults with ADHD) stimulating mainly the dorsolateral prefrontal cortex (dlPFC). We included 12 anodal tDCS studies (232 children and adults with ADHD) in 3 random-effects meta-analyses of cognitive measures of attention, inhibition and processing speed.

RESULTS: The review of rTMS and tDCS showed positive effects in some functions but not others, and little evidence for clinical improvement. The meta-analyses of 1 to 5 sessions of anodal tDCS over mainly the left or bilateral dlPFC showed trend-level improvements in inhibition and processing speed, but not in attention.

LIMITATIONS: Heterogeneity in stimulation parameters, patient age and outcome measures limited the interpretation of findings.

CONCLUSION: The review and meta-analysis showed limited evidence that 1 to 5 sessions of rTMS and tDCS, mostly of the dlPFC, improved clinical or cognitive measures of ADHD. These findings did not support using rTMS or tDCS of the dlPFC as an alternative neurotherapy for ADHD as yet. Larger, multi-session stimulation studies identifying more optimal sites and stimulation parameters in combination with cognitive training could achieve larger effects.
AD  - Westwood, Samuel J. From the Department of Child &amp; Adolescent Psychiatry, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, United Kingdom (Westwood, Rubia); the Institut d&#039;Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain (Radua); the Mental Health Research Networking Centre (CIBERSAM), Madrid, Spain (Radua); the Department of Clinical Neuroscience, Centre for Psychiatric Research and Education, Karolinska Institutet, Tomtebodavagen 18A, Stockholm, Sweden (Radua); and the Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King&#039;s College London, De Crespigny Park, London, United Kingdom (Radua).Radua, Joaquim. From the Department of Child &amp; Adolescent Psychiatry, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, United Kingdom (Westwood, Rubia); the Institut d&#039;Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain (Radua); the Mental Health Research Networking Centre (CIBERSAM), Madrid, Spain (Radua); the Department of Clinical Neuroscience, Centre for Psychiatric Research and Education, Karolinska Institutet, Tomtebodavagen 18A, Stockholm, Sweden (Radua); and the Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King&#039;s College London, De Crespigny Park, London, United Kingdom (Radua).Rubia, Katya. From the Department of Child &amp; Adolescent Psychiatry, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, United Kingdom (Westwood, Rubia); the Institut d&#039;Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain (Radua); the Mental Health Research Networking Centre (CIBERSAM), Madrid, Spain (Radua); the Department of Clinical Neuroscience, Centre for Psychiatric Research and Education, Karolinska Institutet, Tomtebodavagen 18A, Stockholm, Sweden (Radua); and the Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King&#039;s College London, De Crespigny Park, London, United Kingdom (Radua).
AN  - 33009906
AU  - Westwood,
AU  - S.
AU  - J.
AU  - Radua,
AU  - J.
AU  - Rubia,
AU  - K.
DA  - nov 23
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1503/jpn.190179
DP  - Ovid Technologies
J2  - J Psychiatry Neurosci
L1  - internal-pdf://2146699646/Westwood-2020.pdf
LA  - English
N1  - Westwood, Samuel JRadua, JoaquimRubia, Katya
PY  - 2020
SP  - 190179
T2  - Journal of Psychiatry &amp; Neuroscience
TI  - Noninvasive brain stimulation in children and adults with attention-deficit/hyperactivity disorder: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33009906
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33009906&amp;id=doi:10.1503%2Fjpn.190179&amp;issn=1180-4882&amp;isbn=&amp;volume=45&amp;issue=6&amp;spage=190179&amp;pages=190179&amp;date=2020&amp;title=Journal+of+Psychiatry+%26+Neuroscience&amp;atitle=Noninvasive+brain+stimulation+in+children+and+adults+with+attention-deficit%2Fhyperactivity+disorder%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Westwood&amp;pid=%3Cauthor%3EWestwood+SJ%3C%2Fauthor%3E%3CAN%3E33009906%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 45
ER  -
TY  - JOUR
AB  - Diverse studies have investigated the impact of prenatal exposure to vitamin D levels on brain development; however, evidence in humans has never been systematically reviewed. This article summarized evidence of the association between 25-hydroxyvitamin D [25(OH)D] levels in maternal blood in pregnancy or newborn blood at birth and neurodevelopmental outcomes, including cognition, psychomotor performance, language development, behavioral difficulties, attention deficit and hyperactivity disorder (ADHD), and autistic traits. PubMed, Web of Science and SCOPUS databases were systematically searched for epidemiologic studies published through May 2018 using keywords. Random-effects meta-analyses were conducted. Of 260 identified articles, 25 were included in the present review. Comparing the highest vs. the lowest category of prenatal 25(OH)D levels, the pooled beta coefficients were 0.95 (95% CI -0.03, 1.93; p = 0.05) for cognition, and 0.88 (95% CI -0.18, 1.93; p = 0.10) for psychomotor development. The pooled relative risk for ADHD was 0.72 (95% CI, 0.59, 0.89; p = 0.002), and the pooled odds ratio for autism-related traits was 0.42 (95% CI, 0.25, 0.71; p = 0.001). There was little evidence for protective effects of high prenatal 25(OH)D for language development and behavior difficulties. This meta-analysis provides supporting evidence that increased prenatal exposure to 25(OH)D levels is associated with improved cognitive development and reduced risk of ADHD and autism-related traits later in life. Associations represent a potentially high public health burden given the current prevalence of vitamin D deficiency and insufficiency among childbearing aging and pregnant women. Copyright &copy; 2019, Springer Nature Limited.
AD  - (Garcia-Serna, Morales) Biomedical Research Institute of Murcia (IMIB-Arrixaca), Murcia, Spain (Garcia-Serna, Morales) University of Murcia, Murcia, Spain (Morales) CIBER Epidemiologia y Salud Publica (CIBERESP), Madrid, SpainE. Morales, Biomedical Research Institute of Murcia (IMIB-Arrixaca), Murcia, Spain. E-mail: embarto@hotmail.com
AN  - 626219482
AU  - Garcia-Serna,
AU  - A.
AU  - M.
AU  - Morales,
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1038/s41380-019-0357-9
DP  - Ovid Technologies
KW  - adult
KW  - aging
KW  - article
KW  - attention deficit disorder
KW  - autism
KW  - brain development
KW  - cognitive development
KW  - female
KW  - human
KW  - language development
KW  - maternal blood
KW  - Medline
KW  - meta analysis
KW  - newborn
KW  - pregnancy
KW  - pregnant woman
KW  - prenatal exposure
KW  - prevalence
KW  - psychomotor development
KW  - psychomotor performance
KW  - public health
KW  - risk factor
KW  - Scopus
KW  - systematic review
KW  - vitamin D deficiency
KW  - Web of Science
KW  - vitamin D
L1  - internal-pdf://3389971134/Garcia-Serna-2020.pdf
LA  - English
PY  - 2020
SP  - 2468-2481
T2  - Molecular Psychiatry
TI  - Neurodevelopmental effects of prenatal vitamin D in humans: systematic review and meta-analysis
UR  - http://www.nature.com/mp/index.html
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=626219482
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:30696940&amp;id=doi:10.1038%2Fs41380-019-0357-9&amp;issn=1359-4184&amp;isbn=&amp;volume=25&amp;issue=10&amp;spage=2468&amp;pages=2468-2481&amp;date=2020&amp;title=Molecular+Psychiatry&amp;atitle=Neurodevelopmental+effects+of+prenatal+vitamin+D+in+humans%3A+systematic+review+and+meta-analysis&amp;aulast=Garcia-Serna&amp;pid=%3Cauthor%3EGarcia-Serna+A.M.%3C%2Fauthor%3E%3CAN%3E626219482%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://www.nature.com/articles/s41380-019-0357-9
UR  - https://www.nature.com/articles/s41380-019-0357-9.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - **Objectives:** 
This review examines home visiting programmes that specifically provide home based support to vulnerable, socially disadvantaged women who are either pregnant or have recently become a new parent. Home visiting programmes often report multiple outcomes. The purpose of this review is to systematically summarise how effective home visiting programmes are at improving young children&#039;s language development. 

**Data sources:** 
A comprehensive search of four online databases (Embase, Emcare, Psycinfo and Medline) between 1990 and 2020 was conducted, as well as a hand search of the references of relevant studies. 

**Review method:** 
Studies were screened with N = 11 meeting the inclusion/exclusion criteria. The risk of bias of each study was assessed. To enable comparisons between home visiting programmes, relevant data was extracted using an adapted version of the Cochrane Public Health Group Data Extraction and Assessment Template. 

**Results:**
Most of the home visiting programmes had been established in America. Six of the eleven studies reported positive language outcomes for children. Where statistical data was reported, the magnitude of the difference between the intervention and control groups represented small effect sizes. Nine different language measures were used, reporting on varying domains of language development rendering comparisons across programmes difficult. Most studies failed to report the duration of home visits, though studies which started prenatally showed the most promise in improving children&#039;s language development. 

**Conclusion:** 
Home visiting programmes targeted at socially disadvantaged women and their children have the potential to positively influence the language development of the child. This review highlights that not all home visiting programmes measure the impact that the programme has on children&#039;s language development, and not all home visiting programmes achieve positive language outcomes. Initiating visits prenatally may help towards the improvement of children&#039;s language development. Future evaluations of home visiting programmes should explore this finding further, consider the language assessment tools selected, and improve on the reporting of their language results. 
(C) 2020 Elsevier Ltd. All rights reserved.
AN  - WOS:000578971400008
AU  - Henwood,
AU  - T.
AU  - Channon,
AU  - S.
AU  - Penny,
AU  - H.
AU  - Robling,
AU  - M.
AU  - Waters,
AU  - C.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.ijnurstu.2020.103610
L1  - internal-pdf://0860318916/Henwood-2020.pdf
N1  - Henwood, Tom Channon, Sue Penny, Helen Robling, Mike Waters, Cerith S.Channon, Sue/0000-0002-5394-14831873-491x
PY  - 2020
T2  - International Journal of Nursing Studies
TI  - Do home visiting programmes improve children&#039;s language development? A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000578971400008
UR  - https://www.sciencedirect.com/science/article/abs/pii/S002074892030095X?via%3Dihub
VL  - 109
ER  -
TY  - JOUR
AB  - BACKGROUND: 
It is necessary to develop effective preventive interventions before depression established to alleviate depressive symptoms or delay the onset of depression. In this study, we employed Bayesian network meta-analysis to identify the optimal psychosocial intervention approach for preventing depressive symptoms in children and adolescents.

METHODS: 
We searched publication databases and conference abstracts, from time of their inception through April 2019 without language restriction, for randomized controlled trials that compared the efficacy of various psychosocial intervention approaches. We extracted the mean and standard deviation values between baseline and the last observation, and calculated the change score in depression. We also assessed ranking probability by surface under the cumulative ranking curve using a 95% credible interval.

RESULTS: 
A total of 27 randomized controlled trials, involving 5,976 participants aged between 7 to 18 years, were included in our analyses. Analysis of various valid assessment instruments indicated that computer cognitive-behavioral therapy [standard mean difference (SMD = -1.82)], cognitive-behavioral therapy (SMD = -1.54) and interpersonal psychotherapy (SMD = -1.29) were statistically superior to wait-list group. Among the approaches, computer cognitive-behavioral therapy had the highest probability of being the best intervention, based on improvement from baseline to the end of the intervention (SUCRA = 90.47%, CrI: 0.55, 1.00).

LIMITATIONS: 
The results herein may not apply to other cultures and ethnic minorities because about half of the studies included in our analysis were conducted in the United States.

CONCLUSIONS: 
Computer cognitive-behavioral therapy was the most recommended intervention to accompany the depression among children and adolescents according to our Bayesian network meta-analysis results.
AD  - Li, Jing. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China. Electronic address: 348901000@qq.com.Liang, Jing-Hong. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China; Department of Social medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, Jiangsu 215123, P.R. China. Electronic address: 13092616243@163.com.Li, Jia-Yu. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China. Electronic address: 1174870379@qq.com.Qian, Sheng. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China. Electronic address: 736753730@qq.com.Jia, Rui-Xia. Department of Social medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, Jiangsu 215123, P.R. China. Electronic address: 20174247027@stu.suda.edu.cn.Wang, Ying-Quan. Department of Social medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, Jiangsu 215123, P.R. China. Electronic address: 2824854419@qq.com.Xu, Yong. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China; Department of Social medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, Jiangsu 215123, P.R. China. Electronic address: childhealth@suda.edu.cn.
AN  - 33221723
AU  - Li,
AU  - J.
AU  - Liang,
AU  - J.
AU  - H.
AU  - Li,
AU  - J.
AU  - Y.
AU  - Qian,
AU  - S.
AU  - Jia,
AU  - R.
AU  - X.
AU  - Wang,
AU  - Y.
AU  - Q.
AU  - Xu,
AU  - Y.
DA  - Nov 11
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2020.11.023
DP  - Ovid Technologies
J2  - J Affect Disord
L1  - internal-pdf://0794457423/Li-2020.pdf
LA  - English
M3  - Review
N1  - Li, JingLiang, Jing-HongLi, Jia-YuQian, ShengJia, Rui-XiaWang, Ying-QuanXu, YongS0165-0327(20)32953-0
PY  - 2020
SP  - 364-372
T2  - Journal of Affective Disorders
TI  - Optimal approaches for preventing depressive symptoms in children and adolescents based on the psychosocial interventions: A Bayesian Network Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33221723
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33221723&amp;id=doi:10.1016%2Fj.jad.2020.11.023&amp;issn=0165-0327&amp;isbn=&amp;volume=280&amp;issue=&amp;spage=364&amp;pages=364-372&amp;date=2020&amp;title=Journal+of+Affective+Disorders&amp;atitle=Optimal+approaches+for+preventing+depressive+symptoms+in+children+and+adolescents+based+on+the+psychosocial+interventions%3A+A+Bayesian+Network+Meta-Analysis.&amp;aulast=Li&amp;pid=%3Cauthor%3ELi+J%3C%2Fauthor%3E%3CAN%3E33221723%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0165032720329530?via%3Dihub
VL  - 280
ER  -
TY  - JOUR
AB  - Focused intervention practices (FIPs) are widely used to improve social communication skills, as they are specifically aimed at enhancing skills identified as being problematic in children with autism spectrum disorder ASD, such as imitation, eye contact, gestures, joint attention and play. This meta-analysis was performed to ascertain the overall effectiveness of FIPs in children with ASD 6 years of age and younger. Five electronic searches were conducted, 1828 references were retrieved, and 43 studies 59 outcome measures were included in the meta-analysis. Studies included 785 participants 41.6 months with ASD. The overall socio-communicative effect size for each specific skill imitation, joint attention, and play was calculated using the Hedges&#039; g (g) for group design studies, and the Nonoverlap of All Pairs (NAP) for single case design studies. Random-effects metaregression models and correlations were also used to assess whether the results were different according to population and intervention characteristics. The impact of possible publication bias was analysed. The results suggest that, whereas FIPs have medium to large positive effects (g = 0.51; NAP = 0.86), those where caregivers or teachers play an active role (g = 0.50; NAP = 0.89) have medium effect sizes. All social and communicative skills outcomes of FIPs have medium effect sizes (Imitation: g = 0.42, NAP = 0.90; Joint attention: g = 0.54, NAP = 0.86; Play: g = 0.47, NAP = 0.81). Effect sizes were greater when participants&#039; preintervention ages were lower and treatment dosage was higher. When it comes to achieving substantial improvements, factors to be highlighted are the role of caregivers and adaptation of the programme to the characteristics of the child. Implementation of early intervention programmes should be substantiated by a sufficient amount of information about the characteristics of each participant. Professionals should take this information into account in order to select as accurately as possible those procedures that are most effective and feasible. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - Bejarano-Martin, Alvaro: alvaro_beja@usal.es; Canal-Bedia, Ricardo: rcanal@usal.es; Magan-Maganto, Maria: mmmaria@usal.es; Fernandez-Alvarez, Clara: cjf2146@columbia.edu; Loa-Jonsdottir, Sigridur: sigridurloa@greining.is; Saemundsen, Evald: evald@greining.is; Vicente, Astrid: astrid.vicente@insa.min-saude.pt; Cafe, Catia: catiacafe@yahoo.com; Rasga, Celia: celia.rasga@insa.min-saude.pt; Garcia-Primo, Patricia: PGARCIAPRIMO@externos.isciii.es; Posada, Manuel: mposada@isciii.esCanal-Bedia, Ricardo: Centro de Atencion Integral al Autismo (INFOAUTISMO), Facultad de Educacion, Universidad de Salamanca, Paseo Canalejas, 169, Salamanca, Spain, 37008, rcanal@usal.esBejarano-Martin, Alvaro: INICO, Instituto Universitario de Integracion en la Comunidad, Universidad de Salamanca, Salamanca, SpainCanal-Bedia, Ricardo: INICO, Instituto Universitario de Integracion en la Comunidad, Universidad de Salamanca, Salamanca, SpainMagan-Maganto, Maria: INICO, Instituto Universitario de Integracion en la Comunidad, Universidad de Salamanca, Salamanca, SpainFernandez-Alvarez, Clara: INICO, Instituto Universitario de Integracion en la Comunidad, Universidad de Salamanca, Salamanca, SpainLoa-Jonsdottir, Sigridur: State Diagnostic and Counselling Centre, Kopavogur, IcelandSaemundsen, Evald: State Diagnostic and Counselling Centre, Kopavogur, IcelandVicente, Astrid: Instituto Nacional de Saude Doutor Ricardo Jorge, Lisboa, PortugalCafe, Catia: Instituto Nacional de Saude Doutor Ricardo Jorge, Lisboa, PortugalRasga, Celia: Instituto Nacional de Saude Doutor Ricardo Jorge, Lisboa, PortugalGarcia-Primo, Patricia: IIER, Instituto de Salud Carlos III, Madrid, SpainPosada, Manuel: IIER, Instituto de Salud Carlos III, Madrid, Spain
AN  - 2020-21742-038
AU  - Bejarano-Martin,
AU  - Alvaro
AU  - Canal-Bedia,
AU  - Ricardo
AU  - Magan-Maganto,
AU  - Maria
AU  - Fernandez-Alvarez,
AU  - Clara
AU  - Loa-Jonsdottir,
AU  - Sigridur
AU  - Saemundsen,
AU  - Evald
AU  - Vicente,
AU  - Astrid
AU  - Cafe,
AU  - Catia
AU  - Rasga,
AU  - Celia
AU  - Garcia-Primo,
AU  - Patricia
AU  - Posada,
AU  - Manuel
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ecresq.2020.01.004
DP  - Ovid Technologies
KW  - Autism spectrum disorder, Socio-communication skills, Intervention, Meta-analysis, Efficacy
KW  - *Autism Spectrum Disorders
KW  - *Intervention
KW  - *Social Communication
KW  - Interpersonal &amp; Client Centered &amp; Humanistic Therapy [3314]
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://2862511148/Bejarano-Martin-2020-Efficacy of focused socia.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2020
SP  - 430-445
T2  - Early Childhood Research Quarterly
TI  - Efficacy of focused social and communication intervention practices for young children with autism spectrum disorder: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2020-21742-038
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.ecresq.2020.01.004&amp;issn=0885-2006&amp;isbn=&amp;volume=51&amp;issue=&amp;spage=430&amp;pages=430-445&amp;date=2020&amp;title=Early+Childhood+Research+Quarterly&amp;atitle=Efficacy+of+focused+social+and+communication+intervention+practices+for+young+children+with+autism+spectrum+disorder%3A+A+meta-analysis.&amp;aulast=Bejarano-Martin&amp;pid=%3Cauthor%3EBejarano-Martin%2C+Alvaro%3C%2Fauthor%3E%3CAN%3E2020-21742-038%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/272055/1-s2.0-S0885200619X00046/1-s2.0-S0885200620300041/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEK%2F%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQCYoch3fid2vjt1VYQPaP6elzGCPiGV78zYUWYXgV%2BXAQIhANWgO4W5eJfjDGYhN0%2FeHbyZX6LvQladuEm6SjYwpQ%2B0KrQDCCcQAxoMMDU5MDAzNTQ2ODY1IgydQRk7X7x0VmoMHZ4qkQMU62TSERz3puAvjg0HzBQ9f3fY5rgIpUDGanvdTI%2FZy%2BhCKku9LlHGYokyyM517hnNhRpsFvKLhk4Hb659sB5aUyorqNlJZnTQtIbhTTuJ7DbTTM2P8yqXSidy3miulgFAB4xqb5XowHbW24GArycot%2BADcuWD1ApkrJqj1QRYnWnVAWTWR3r88BpdMY45PxXjj3JwkNLilzXePc4n4sebzcJuHMLrg8nfUk53qgLfWF3QvVGTLJXYEVYb8hUs%2F0vUjGyp7csYSyCwm4H7YJmpH7V5y56ndFSvHA8Gmt62SyK%2B13%2Bn5XdCf6AMwFeKfwWXreVycvl%2BLFq51QIhE7eOfZhQbskUA4lTntvW%2FieSInmJlToU4s6%2F5REol3gvJAYvYopF8pnmapmlzjt2bdoHmyxWL2HVPA2Z3yN3YXk4Jv%2FZ5Y8OaaT%2FGNriuy8MsfH17lW17J5QCfDotnA%2FMCZy9Dp90pHhWXObx1WNZ%2F4NIESDW1QlJsxRWRFkTQAoGyTPcVBzsN2TEjVKhdigRMJFYjDz8IH3BTrqAQhgypEe6AC%2BYG16tBTY3uAeKMY4hnzxJPAFiJho6KNU5r1te44Wdhwd5QrAZPKLasdG%2FTm7gwv%2BeFmXsQVIyuPVJJhCnxjrSoSF%2FYF4lUo%2FOOpJtg0vZVfd6%2B7WH0EFIqh95L49DUA4A6SgrJvELadvlAywAq0DujY%2FDglzfxhb2UqvEL%2FGgGMqPfAuZRTvHD7DGiq3vfmPNZT4CapZCm5HaQmmAo%2ByiO6a7TjxTDIkWW5eY810eUa4%2BefZQMJBBk7fKc5fbvYXTSoUM24LmqMv%2BtrOkb4kTAA216yDSIQfAUwX%2F3iEymfc5A%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200610T065317Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY5EMXBNDQ%2F20200610%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=cdd07f7ee0b1a622cdb79b59f0fe4e4be9e8f91660a24715c5f323918cffe5b7&amp;hash=11eaf4a706a1b7af2a71b1280070adefda97600e040f27d6b14d3d0c0075fcaf&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0885200620300041&amp;tid=spdf-f3d512e0-e738-4e9c-be65-a88367ed2e3f&amp;sid=b6715d5b8d7fc143477ae8442de16298848bgxrqb&amp;type=client
VL  - 51
ER  -
TY  - JOUR
AB  - Parental reflective functioning (PRF) is an important predictor of infant attachment, and interventions that target parent-infant/toddler dyads who are experiencing significant problems have the potential to improve PRF. A range of dyadic interventions have been developed over the past two decades, some of which explicitly target PRF as part of their theory of change, and some that do not explicitly target PRF, but that have measured it as an outcome. However, no meta-analytic review of the impact of these interventions has been carried out to date. The aim of this review was to evaluate the effectiveness of dyadic interventions targeting parents of infant and toddlers, in improving PRF and a number of secondary outcomes. A systematic review and meta-analysis was conducted in which key electronic databases were searched up to October 2018. Eligible studies were identified and data extracted. Data were synthesised using meta-analysis and expressed as both effect sizes and risk ratios. Six studies were identified providing a total of 521 participants. The results of six meta-analyses showed a nonsignificant moderate improvement in PRF in the intervention group (standardised mean difference [SMD]: -0.46; 95% confidence interval [CI] [-0.97, 0.04]) and a significant reduction in disorganised attachment (risk ratio: 0.50; 95% CI [0.27, 0.90]). There was no evidence for intervention effects on attachment security (odds ratio: 0.71; 95% CI [0.19, 2.64]), parent-infant interaction (SMD: -0.10; 95% CI [-0.46, 0.26]), parental depression (SMD: -1.55; 95% CI [-3.74, 0.64]) or parental global distress (SMD: -0.19, 95% CI [-3.04, 22.65]). There were insufficient data to conduct subgroup analysis (i.e. to compare the effectiveness of mentalisation-based treatment with non-mentalization-based treatment interventions). Relational early interventions may have important benefits in improving PRF and reducing the prevalence of attachment disorganisation. The implications for future research are discussed.
AD  - Barlow, Jane. Department of Social Policy and Intervention, University of Oxford, Oxford, UK.Sleed, Michelle. Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.Sleed, Michelle. Anna Freud Centre, London, UK.Midgley, Nick. Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.Midgley, Nick. Anna Freud Centre, London, UK.
AN  - 33210359
AU  - Barlow,
AU  - J.
AU  - Sleed,
AU  - M.
AU  - Midgley,
AU  - N.
DA  - Nov 18
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/imhj.21896
DP  - Ovid Technologies
J2  - Infant Ment Health J
L1  - internal-pdf://2134254001/Barlow-2020-Enhancing parental reflective func.pdf
LA  - English
N1  - Using Smart Source ParsingNovBarlow, JaneSleed, MichelleMidgley, Nick
PY  - 2020
SP  - 18
T2  - Infant Mental Health Journal
TI  - Enhancing parental reflective functioning through early dyadic interventions: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33210359
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33210359&amp;id=doi:10.1002%2Fimhj.21896&amp;issn=0163-9641&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Infant+Mental+Health+Journal&amp;atitle=Enhancing+parental+reflective+functioning+through+early+dyadic+interventions%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Barlow&amp;pid=%3Cauthor%3EBarlow+J%3C%2Fauthor%3E%3CAN%3E33210359%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/imhj.21896?download=true
VL  - 18
ER  -
TY  - JOUR
AB  - Cognitive behavioral therapy (CBT) has received considerable empirical support for internalizing disorders including anxiety, depression, obsessive-compulsive disorder, and post-traumatic stress disorder in children and adolescents. However, there is less knowledge regarding how CBT performs when delivered in routine clinical care. A systematic review and meta-analysis was conducted of CBT for internalizing disorders in children and adolescents in routine clinical care. Ovid MEDLINE, Embase OVID, and PsycINFO were systematically searched for articles published until October 2019. The effectiveness of CBT, methodological quality, and moderators of treatment outcome were examined. The effects of CBT in routine clinical care were benchmarked by comparing with efficacy studies for the same disorders. Fifty-eight studies were included, comprising 4618 participants. Large effect sizes for outcome were detected at post-treatment (g = 1.28-2.54), and follow-up (g = 1.72-3.36). Remission rates across diagnoses ranged from 50.7% - 77.4% post-treatment, to 53.5% -83.3% at follow-up. Attrition rate across the disorders was 12.2%. Quality of the included studies was fair, and heterogeneity was high. Similarities between the effectiveness and efficacy studies were greater than the differences in outcome. CBT delivered in routine clinical care is efficacious in reducing internalizing disorders and symptoms. The outcomes are comparable with results obtained in efficacy studies. PROSPERO registration: ID CRD42019128709.
AD  - Wergeland, Gro Janne H. Department of Child and Adolescent Psychiatry, Division of Psychiatry, Haukeland University Hospital, Jonas Lies vei 65, N-5021 Bergen, Norway; Department of Clinical Medicine, Faculty of Medicine, University of Bergen, N-5021 Bergen, Norway. Electronic address: gro.wergeland@uib.no.Riise, Eili N. Department of Child and Adolescent Psychiatry, District General Hospital of Forde, Svanehaugvegen 2, N-6812 Forde, Norway.Ost, Lars-Goran. Department of Psychology, Stockholm University, SE-106 91 Stockholm, Sweden; OCD-Team, Haukeland University Hospital, Jonas Lies vei 65, N-5021 Bergen, Norway.
AN  - 33186776
AU  - Wergeland,
AU  - G.
AU  - J.
AU  - H.
AU  - Riise,
AU  - E.
AU  - N.
AU  - Ost,
AU  - L.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.cpr.2020.101918
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://0970761263/Wergeland-2020.pdf
LA  - English
M3  - Review
N1  - Wergeland, Gro Janne HRiise, Eili NOst, Lars-GoranS0272-7358(20)30106-9
PY  - 2020
SP  - 101918
T2  - Clinical Psychology Review
TI  - Cognitive behavior therapy for internalizing disorders in children and adolescents in routine clinical care: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33186776
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33186776&amp;id=doi:10.1016%2Fj.cpr.2020.101918&amp;issn=0272-7358&amp;isbn=&amp;volume=83&amp;issue=&amp;spage=101918&amp;pages=101918&amp;date=2020&amp;title=Clinical+Psychology+Review&amp;atitle=Cognitive+behavior+therapy+for+internalizing+disorders+in+children+and+adolescents+in+routine+clinical+care%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Wergeland&amp;pid=%3Cauthor%3EWergeland+GJH%3C%2Fauthor%3E%3CAN%3E33186776%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 83
ER  -
TY  - JOUR
AB  - Omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA) supplementation in the cardiovascular field is effective if a certain Omega-3 index (O3I) is achieved or the daily n-3 LCPUFA dose is high enough. Whether this applies to studies on cognition in children and adolescents is unclear. The aims of the current review were to investigate whether: (1) a certain O3I level and (2) a minimum daily n-3 LCPUFA dose are required to improve cognition in 4-25 year olds. Web of Science and PubMed were searched. Inclusion criteria: placebo controlled randomized controlled trial; participants 4-25 years; supplementation with docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA); assessing cognition; in English and &gt;= 10 participants per treatment arm. Thirty-three studies were included, 21 in typically developing participants, 12 in those with a disorder. A positive effect on cognitive measures was more likely in studies with an increase in O3I to &gt;6%. Half of the studies in typically developing children with daily supplementation dose &gt;= 450 mg DHA + EPA showed improved cognition. For children with a disorder no cut-off value was found. In conclusion, daily supplementation of &gt;= 450 mg DHA + EPA per day and an increase in the O3I to &gt;6% makes it more likely to show efficacy on cognition in children and adolescents.
AN  - WOS:000585449200001
AU  - van
AU  - der
AU  - Wurff,
AU  - I.
AU  - S.
AU  - M.
AU  - Meyer,
AU  - B.
AU  - J.
AU  - de
AU  - Groot,
AU  - R.
AU  - H.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3390/nu12103115
L1  - internal-pdf://0793354280/van der Wurff-2020-Effect of Omega-3 Long Chai.pdf
N1  - van der Wurff, Inge S. M. Meyer, Barbara J. de Groot, Renate H. M.Meyer, Barbara J/0000-0001-7962-7890; de Groot, Renate/0000-0002-3734-25602072-6643
PY  - 2020
T2  - Nutrients
TI  - Effect of Omega-3 Long Chain Polyunsaturated Fatty Acids (n-3 LCPUFA) Supplementation on Cognition in Children and Adolescents: A Systematic Literature Review with a Focus on n-3 LCPUFA Blood Values and Dose of DHA and EPA
UR  - &lt;Go to ISI&gt;://WOS:000585449200001
UR  - https://res.mdpi.com/d_attachment/nutrients/nutrients-12-03115/article_deploy/nutrients-12-03115-v3.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - **Background:** 
Children and adolescents with obesity experience social discrimination which can contribute to increased depression, reduced self-esteem and poor body image. Physical activity improves these psychological outcomes but its ability to affect such changes in the context of pediatric obesity treatment is unknown. The primary aim of this systematic review was to determine how structured physical activity interventions, in the context of pediatric obesity treatment, affect changes in depression, self-esteem and body image. 

**Method(s):** 
A systematic search of published literature up to June 2019 was undertaken using electronic databases MEDLINE, EMBASE, Cochrane Library and PsychINFO. Eligible studies included a supervised moderate-to-vigorous physical activity intervention conducted at least weekly in free-living children or adolescents (&lt;=18 years) with overweight or obesity, reporting depression, self-esteem and/or body image pre- and post-intervention using validated tools. Meta-analysis, using random effects, was used to combine outcome data and moderator analysis conducted to identify intervention characteristics that may influence outcomes. 

**Result(s):** 
Of 3078 articles screened, 29 studies were included in the review. Overall, structured physical activity interventions were associated with reduced depression (SMD [SE] -0.34 [0.06], p &lt; 0.001, I&lt;sup&gt;2&lt;/sup&gt; = 77%), increased self-esteem (0.34 [0.04], p &lt; 0.001, I&lt;sup&gt;2&lt;/sup&gt; = 78%) and improved body image (0.47 [0.05], p &lt; 0.001, I&lt;sup&gt;2&lt;/sup&gt; = 56%). Age, weight-related changes and inclusion of a nutrition or behavioural component did not significantly influence findings, while school settings and longer interventions produced the greatest self-esteem improvements. 

**Conclusion(s):** 
Structured physical activity interventions, in the context of pediatric obesity treatment, improve depression, self-esteem and body image. Copyright &copy; 2020 Elsevier Ltd
AD  - (King) The University of Sydney, Nutrition and Dietetics Group, School of Life and Environmental Sciences, Faculty of Science, Camperdown, NSW 2006, Australia (Jebeile, Garnett, Baur, Gow) The University of Sydney Children&#039;s Hospital Westmead Clinical School, Westmead, NSW 2145, Australia (Jebeile, Garnett, Gow) Institute of Endocrinology and Diabetes, The Children&#039;s Hospital at Westmead, NSW 2145, Australia (Baur) Weight Management Services, The Children&#039;s Hospital at Westmead, NSW 2145, Australia (Paxton) School of Psychology and Public Health, La Trobe University, Melbourne, VIC 3086, AustraliaM.L. Gow, The University of Sydney Children&#039;s Hospital Westmead Clinical School, Westmead, NSW 2145, Australia. E-mail: megan.gow@health.nsw.gov.au
AN  - 2006916336
AU  - King,
AU  - J.
AU  - E.
AU  - Jebeile,
AU  - H.
AU  - Garnett,
AU  - S.
AU  - P.
AU  - Baur,
AU  - L.
AU  - A.
AU  - Paxton,
AU  - S.
AU  - J.
AU  - Gow,
AU  - M.
AU  - L.
DA  - October
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.mhpa.2020.100342
DP  - Ovid Technologies
KW  - Body image
KW  - Depression
KW  - Obesity
KW  - Pediatric
KW  - Physical activity
KW  - Self-esteem
KW  - aerobic exercise
KW  - article
KW  - behavior change
KW  - childhood obesity/th [Therapy]
KW  - diet therapy
KW  - exercise intensity
KW  - healthy diet
KW  - human
KW  - meta analysis
KW  - nutrition education
KW  - priority journal
KW  - psychological well-being
KW  - resistance training
KW  - self esteem
KW  - systematic review
L1  - internal-pdf://0459834191/King.pdf
LA  - English
PY  - 2020
T2  - Mental Health and Physical Activity
TI  - Physical activity based pediatric obesity treatment, depression, self-esteem and body image: A systematic review with meta-analysis
UR  - http://www.elsevier.com
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2006916336
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.mhpa.2020.100342&amp;issn=1755-2966&amp;isbn=&amp;volume=19&amp;issue=&amp;spage=100342&amp;pages=&amp;date=2020&amp;title=Mental+Health+and+Physical+Activity&amp;atitle=Physical+activity+based+pediatric+obesity+treatment%2C+depression%2C+self-esteem+and+body+image%3A+A+systematic+review+with+meta-analysis&amp;aulast=King&amp;pid=%3Cauthor%3EKing+J.E.%3C%2Fauthor%3E%3CAN%3E2006916336%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
VL  - 19 (no pagination)
ER  -
TY  - JOUR
AB  - **Background**
As preterm infants do not experience the nutrient accretion and rapid growth phase of the third trimester of pregnancy, they are vulnerable to postnatal nutritional deficits, including of fat. Consequently, they require higher fat intakes compared to their full term counterparts to achieve adequate growth and development. Human milk fat provides the major energy needs of the preterm infant and also contributes to several metabolic and physiological functions. Although human milk has many benefits for this population, its fat content is highly variable and may be inadequate for their optimum growth and development. This is a 2020 update of a Cochrane Review last published in 2000.

**Objectives**
To determine whether supplementation of human milk with fat compared with unsupplemented human milk fed to preterm infants improves growth, body composition, cardio‐metabolic, and neurodevelopmental outcomes without significant adverse effects.

**Search methods**
We used the standard search strategy of Cochrane Neonatal to search Cochrane Central Register of Controlled Trials (CENTRAL 2019, Issue 8) in the Cochrane Library and MEDLINE via PubMed on 23 August 2019. We also searched clinical trials databases and the reference lists of retrieved articles for randomised controlled trials and quasi‐randomised trials.

**Selection criteria**
Published and unpublished randomised controlled trials were eligible if they used random or quasi‐random methods to allocate preterm infants fed human milk in hospital to supplementation or no supplementation with additional fat.

**Data collection and analysis**
No new randomised controlled trials matching the selection criteria were found but we extracted data from the previously included trial due to changes in review outcomes from when the protocol was first published. Two reviewers independently abstracted data, assessed trial quality, and the quality of evidence at the outcome level using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) criteria. We planned to perform meta‐analyses using risk ratio (RR) for dichotomous data and mean difference (MD) for continuous data, with their respective 95% confidence intervals (CIs). We planned to use a fixed‐effect model and to explore potential causes of heterogeneity via sensitivity analyses.

**Main results**
One randomised trial involving 14 preterm infants was included. There was no evidence of a clear difference between the fat‐supplemented and unsupplemented groups in in‐hospital rates of growth in weight (MD 0.6 g/kg/day, 95% CI &minus;2.4 to 3.6; 1 RCT, n = 14 infants, very low‐quality evidence), length (MD 0.1 cm/week, 95% CI &minus;0.08 to 0.3; 1 RCT, n = 14 infants, very low‐quality evidence) and head circumference (MD 0.2 cm/week, 95% CI &minus;0.07 to 0.4; 1 RCT n = 14 infants, very low‐quality evidence). There was no clear evidence that fat supplementation increased the risk of feeding intolerance (RR 3.0, 95% CI 0.1 to 64.3; 1 RCT, n = 16 infants, very low‐quality evidence). No data were available regarding the effects of fat supplementation on long‐term growth, body mass index, body composition, neurodevelopmental, or cardio‐metabolic outcomes.

**Authors&#039; conclusions**
The one included trial suggests no evidence of an effect of fat supplementation of human milk on short‐term growth and feeding intolerance in preterm infants. However, the very low‐quality evidence, small sample size, few events, and low precision diminishes our confidence that these results reflect the true effect of fat supplementation of human milk in preterm infants, and no long‐term outcomes were reported. Further high‐quality research should evaluate the effect on short and long‐term growth, neurodevelopmental and cardio‐metabolic outcomes in the context of the development of multicomponent fortifiers. Optimal dosage, adverse effects, and delivery practices should also be evaluated.
AU  - Amissah,
AU  - E.
DA  - Aug 2020
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD000341.pub3
L1  - internal-pdf://3336848486/Amissah_et_al-2020-Cochrane_Database_of_System.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Fat supplementation of human milk for promoting growth in preterm infants
ER  -
TY  - JOUR
AB  - Bakgrunn
Traumefokusert kognitiv atferdsterapi (TF-CBT) er en behandlingsmetode for barn og ungdom (3-18 år) som har opplevd ett eller flere traumer, og som utvikler traumerelaterte vansker som følge av dette (Cohen, Mannarino &amp; Deblinger, 2017). Formålet med behandlingen er å redusere posttraumatiske stress symptomer (PTSS), samt angst, depresjon, skamfølelse, eksternaliserende vansker og posttraumatisk sorg. TF-CBT er et manualisert behandlingstiltak som gis gjennom spesialisthelsetjenesten og andre instanser (f.eks. Statens Barnehus). Tilbudet gis individuelt og går over 10-15 timer (eller lengre ved behov). Foresatte inkluderes i behandlingen ved at de følger barnets behandling i parallelle forløp både med felles timer og timer for foresatte. Barnet og foresatte lærer ferdigheter som kan hjelpe dem å redusere stress, og å bearbeide og forholde seg til tankene, atferden og følelsene knyttet til traumehendelsene. En engelsk behandlingsmanual (Cohen, Mannarino &amp; Deblinger, 2006; Cohen, Mannarino &amp; Deblinger, 2017) foreligger. Denne er oversatt til norsk (Cohen, Mannarino &amp; Deblinger, 2018). Rettighetshaver i Norge er Nasjonalt kunnskapssenter om vold og traumatisk stress (NKVTS; www.nkvts.no). Artikkelen er en revisjon av tidligere beskrivelse av samme tiltak i Ungsinn (Kornør, 2013), men videreutviklet ut fra nye prosedyrer og kriterier i Ungsinn fra 2016 (Martinussen m. fl., 2016). Formålet med denne artikkelen er å undersøke om TF-CBT er effektiv som behandlingsmetode i vanlig klinisk praksis i Norge.

Metode
Foreliggende kunnskapsoppsummering bygger på systematisk litteratursøk i databasene Embase, Medline, Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS, SweMed, Kunnskapssenteret, NREPP, NICE, Blueprint og CEBC. I tillegg gjennomførte forfatterne av denne artikkelen andre relevante søk. Det ble også innhentet informasjon fra fagansvarlige for programmet ved Nasjonalt kunnskapssenter om vold og traumatisk stress (NKVTS).

Resultater
Resultatene omfatter en oppsummering av tiltakets beskrivelse, foreliggende norske forskningsstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Tiltakets bakgrunn, innhold og metoder er beskrevet i Cohen, Mannarino og Deblinger (2017). Tiltaket har god teoretisk forankring. Det foreligger en rekke kvalitetsmessig gode internasjonale effektstudier og metaanalyser av det opprinnelige amerikanske tiltaket, hvor effekt av tiltaket er dokumentert. Det har vært gjennomført &eacute;n randomisert kontrollert studie (RCT) av TF-CBT i Norge der ordinær behandling ble gitt som kontrollbetingelse (Jensen m. fl, 2014). Resultatene viste middels store effekter av TF-CBT på flere utfallsmål sammenlignet med vanlig behandling. Dette gjaldt både for PTSD-symptomer og sekundærutfallsmålene: daglig fungering, depressive symptomer og generelle psykiske helseproblemer. Ved behandlingslutt var det signifikant færre pasienter med PTSD diagnose i TF-CBT sammenlignet med vanlig behandling. Det var ingen forskjeller mellom TF-CBT og vanlig behandling i angstsymptomer ved behandlingsslutt. En oppfølgingsstudie av effekten av TF-CBT målt 18 måneder etter behandling (Jensen, Holt, Ormhaug, 2017) viser at symptomforbedringen hos de som fikk TF-CBT ble opprettholdt på oppfølgingstidspunktet. Ved 18 måneders oppfølging rapporterte de som fikk TF-CBT signifikant lavere nivå av generelle psykiske vansker enn kontrollgruppen, men man fant ikke signifikante forskjeller mellom de to behandlingsbetingelsene på andre utfallsmål. Videre hadde de som fikk TF-CBT raskere funksjonsforbedring (bedring i relasjoner med venner, familie, og funksjon i skole- og fritidsammenheng). De hadde også hatt færre behandlingstimer enn kontrollgruppen i ordinær behandling. Den norske studien vurderes som metodisk god og har resultater som tilsvarer funn fra utenlandske studier. Programmet er tilgjengelig gjennom rettighetshaver (NKVTS). Det er krav til opplæring og sertifisering, og en implementeringsplan for spesialisthelsetjenesten foreligger.

Konklusjon
TF-CBT er et tiltak med god teoretisk forankring. Tiltaket er godt beskrevet. Tiltaket har god effekt dokumentert gjennom en rekke internasjonale effektstudier, kunnskapsoppsummeringer og metaanalyser, samt gjennom en norsk effektstudie av metodisk høy kvalitet (inklusive 18 måneders oppfølgingsdata). En rekke systematiske oversikter anbefaler tiltaket som en effektiv behandling for barn og ungdom som har opplevd en eller flere traumer og som utvikler traumerelaterte vansker som følger av dette. Det foreligger en implementeringsplan for tiltaket. Tiltaket har blitt implementert med grundig trening, veiledning og med et system for å sjekke terapeutenes etterlevelse og kompetanse (fidelity) i bruken av programmet.

Tiltaket brukt med unge i alderen 10-18 klassifiseres på evidensnivå 5: Tiltak med sterk dokumentasjon på effekt.

Det presiseres at kunnskapsgrunnlaget gjelder for barn i alderen 10-18 år da det ikke foreligger studier på TF-CBT i Norge med barn under 10 år. Kunnskapsgrunnlaget i en norsk kontekst er også svakere for gutter ut fra at det er et mindretall av gutter inkludert i studien.
AU  - Bjåstad,
AU  - J.,
AU  - F.,
AU  - Haugland,
AU  - B.,
AU  - S.,
AU  - Kornør,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2020
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Traumefokusert kognitiv atferdsterapi (TF-CBT) (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/traumefokusert-kognitiv-atferdsterapi-tf-cbt-2-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by major impairments in social communication, stereotyped and ritualistic behaviors and deficits in sensory reactivity. Recently, noninvasive brain stimulation (NIBS) methods, namely transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS), have been examined as possible new therapeutic options for modifying the pathological neuroplasticity involved in neuropsychiatric disorders including ASD. 

Therefore, we conducted a systematic review on the therapeutic uses of tDCS and repetitive TMS (rTMS) in ASD patients. A systematic search was performed on Scopus, Web of Science, PubMed, Cochrane and Embase. Original articles reporting the use of tDCS or rTMS to treat ASD were screened and studied by two researchers independently based on PRISMA guidelines.

 We found 32 eligible studies including 8 tDCS reports, 23 rTMS reports and one report with both tDCS and rTMS. These studies comprised 6 case-reports, 9 non-controlled trials and 17 controlled trials which assessed NIBS effects on the three cognitive, behavioral and biological dimensions in ASD. 

Existing evidence demonstrates that NIBS methods could be helpful for treating some dimensions of ASD such as repetitive behavior, sociability or some aspects of executive and cognitive functions. However, such evidence should be regarded with care because of the quality of original researches and serious publication bias as well as the heterogeneity of data. Further randomized, double-blind, sham-controlled trials with appropriate follow-up periods should be designed to assess the efficacy of NIBS methods for ASD treatment. Copyright &copy; 2020, Korean College of Neuropsychopharmacology
AD  - (Khaleghi, Zarafshan, Mohammadi) Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Iran, Islamic Republic of (Vand) Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran, Islamic Republic ofA. Khaleghi, Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, South Kargar Ave., Tehran 1333795914, Iran, Islamic Republic of. E-mail: alikhaleghi_bme84@yahoo.com
AN  - 2010085260
AU  - Khaleghi,
AU  - A.
AU  - Zarafshan,
AU  - H.
AU  - Vand,
AU  - S.
AU  - R.
AU  - Mohammadi,
AU  - M.
AU  - R.
DA  - November
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.9758/CPN.2020.18.4.527
DP  - Ovid Technologies
KW  - Autism
KW  - Brain
KW  - Non-invasive neurostimulation
KW  - Transcranial direct current stimulation
KW  - Transcranial magnetic stimulation
KW  - adolescent
KW  - adult
KW  - autism/th [Therapy]
KW  - behavior assessment
KW  - biological activity
KW  - case report
KW  - child
KW  - Cochrane Library
KW  - cognition
KW  - compulsion
KW  - controlled study
KW  - crossover procedure
KW  - executive function
KW  - female
KW  - human
KW  - hyperactivity
KW  - irritability
KW  - lethargy
KW  - major clinical study
KW  - male
KW  - Medline
KW  - Preferred Reporting Items for Systematic Reviews and Meta-Analyses
KW  - preschool child
KW  - psychosocial withdrawal
KW  - publication bias
KW  - randomized controlled trial
KW  - review
KW  - school child
KW  - Scopus
KW  - speech disorder
KW  - stereotypy
KW  - systematic review
KW  - Web of Science
KW  - young adult
L1  - internal-pdf://3363639458/Khaleghi-2020.pdf
LA  - English
M3  - Review
PY  - 2020
SP  - 527-552
T2  - Clinical Psychopharmacology and Neuroscience
TI  - Effects of Non-invasive Neurostimulation on Autism Spectrum Disorder: A Systematic Review
UR  - http://www.cpn.or.kr/journal/view.html?doi=10.9758/cpn.2020.18.4.527
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2010085260
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.9758%2FCPN.2020.18.4.527&amp;issn=1738-1088&amp;isbn=&amp;volume=18&amp;issue=4&amp;spage=527&amp;pages=527-552&amp;date=2020&amp;title=Clinical+Psychopharmacology+and+Neuroscience&amp;atitle=Effects+of+Non-invasive+Neurostimulation+on+Autism+Spectrum+Disorder%3A+A+Systematic+Review&amp;aulast=Khaleghi&amp;pid=%3Cauthor%3EKhaleghi+A.%3C%2Fauthor%3E%3CAN%3E2010085260%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609207/pdf/CPN-18-527.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - This meta-analysis examined the effects of the Early Start Denver Model (ESDM) for young children with autism on developmental outcome measures. The 12 included studies reported results from 640 children with autism across 44 unique effect sizes. The aggregated effect size, calculated using a robust variance estimation meta-analysis, was 0.357 (p = 0.024), which is a moderate effect size with a statistically significant overall weighted averaged that favored participants who received the ESDM compared to children in control groups, with moderate heterogeneity across studies. This result was largely driven by improvements in cognition (g = 0.412) and language (g = 0.408). There were no significant effects observed for measures of autism symptomology, adaptive behavior, social communication, or restrictive and repetitive behaviors. Copyright &copy; 2020 by the authors. Licensee MDPI, Basel, Switzerland.
AD  - (Fuller, Oliver, Vejnoska, Rogers) Department of Psychiatry and Behavioral Sciences, University of California, Davis MIND Institute, Sacramento, CA 95817, United StatesS.J. Rogers, Department of Psychiatry and Behavioral Sciences, University of California, Davis MIND Institute, Sacramento, CA 95817, United States. E-mail: sjrogers@ucdavis.edu
AN  - 2004559850
AU  - Fuller,
AU  - E.
AU  - A.
AU  - Oliver,
AU  - K.
AU  - Vejnoska,
AU  - S.
AU  - F.
AU  - Rogers,
AU  - S.
AU  - J.
DA  - June
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3390/brainsci10060368
DP  - Ovid Technologies
KW  - Autism
KW  - Early intervention
KW  - Early start denver model
KW  - adaptive behavior
KW  - attention deficit disorder
KW  - Autism Diagnostic Observation Schedule
KW  - child
KW  - Childhood Autism Rating Scale
KW  - cognition
KW  - follow up
KW  - gestational age
KW  - human
KW  - interpersonal communication
KW  - intervention study
KW  - language
KW  - meta analysis
KW  - outcome assessment
KW  - quality control
KW  - questionnaire
KW  - review
KW  - social behavior
KW  - social competence
KW  - systematic review
KW  - Communication and Symbolic Behavior Scale
KW  - developmental quotient
KW  - Griffith Developmental Scale
KW  - Restrictive and Repetitive Behavior
KW  - symptomology
KW  - Vineland Adaptive Behavior Scale
L1  - internal-pdf://1228550383/Fuller-2020-The effects of the early start den.pdf
LA  - English
M3  - Review
PY  - 2020
SP  - 1-20
T2  - Brain Sciences
TI  - The effects of the early start denver model for children with autism spectrum disorder: A meta-analysis
UR  - https://www.mdpi.com/2076-3425/10/6/368/pdf
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2004559850
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.3390%2Fbrainsci10060368&amp;issn=2076-3425&amp;isbn=&amp;volume=10&amp;issue=6&amp;spage=1&amp;pages=1-20&amp;date=2020&amp;title=Brain+Sciences&amp;atitle=The+effects+of+the+early+start+denver+model+for+children+with+autism+spectrum+disorder%3A+A+meta-analysis&amp;aulast=Fuller&amp;pid=%3Cauthor%3EFuller+E.A.%3C%2Fauthor%3E%3CAN%3E2004559850%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://res.mdpi.com/d_attachment/brainsci/brainsci-10-00368/article_deploy/brainsci-10-00368-v2.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - OBJECTIVES: To use a quantitative approach to examine the effects of chronic physical activity (PA) interventions on executive functions (EFs) in children aged 3-7 years.DESIGN: Systematic review and meta-analysis.

METHODS: PubMed, EMBASE, Cochrane Central Register of Controlled Trials, PsycINFO, and the China National Knowledge Infrastructure were searched from their inception to December 2019. Intervention studies with a control group that examined the effects of chronic PA interventions on EFs among children aged 3-7 years were included in this meta-analysis. Lastly, subgroup analyses were conducted to examine the potential modifying effects of chronic PA intervention&#039;s characteristics and study quality.

RESULTS: A total of 10 studies were included in this meta-analysis with a total of 716 participants. The fixed-effects model was used to estimate the pooled effect sizes since heterogeneity across included studies was not significant. The summary effects revealed that chronic PA interventions have a small but positive effects on participants&#039; overall EFs [standardized mean difference (SMD)=0.35, 95% CI: 0.20-0.50] as well as inhibition (SMD=0.37, 95% CI: 0.12-0.62) and working memory (SMD=0.24, 95% CI: 0.02-0.46) domains and a moderate effect on the cognitive flexibility domain (SMD=0.66, 95% CI: 0.28-1.05). Lastly, the pooled effect was not significantly modified by intervention duration, session length, or frequency.

CONCLUSIONS: Chronic PA interventions, especially PA plus cognitive challenges interventions, may be a promising way to promote the development of multiple aspects of EFs in children aged 3-7 years.
AD  - Li, Longkai. School of Kinesiology, Shanghai University of Sport, China.Zhang, Jinming. College of Sport Medicine and Rehabilitation, Shandong First Medical University &amp; Shandong Academy of Medical Sciences, China.Cao, Meng. School of Physical Education and Sports Training, Shanghai University of Sport, China.Hu, Wenwen. School of Kinesiology, Shanghai University of Sport, China.Zhou, Tang. School of Kinesiology, Shanghai University of Sport, China.Huang, Tao. Department of Physical Education, Shanghai Jiao Tong University, China.Chen, Peijie. School of Kinesiology, Shanghai University of Sport, China. Electronic address: chenpeijie@sus.edu.cn.Quan, Minghui. School of Kinesiology, Shanghai University of Sport, China. Electronic address: quanminghui@163.com.
AN  - 32360243
AU  - Li,
AU  - L.
AU  - Zhang,
AU  - J.
AU  - Cao,
AU  - M.
AU  - Hu,
AU  - W.
AU  - Zhou,
AU  - T.
AU  - Huang,
AU  - T.
AU  - Chen,
AU  - P.
AU  - Quan,
AU  - M.
DA  - Oct
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jsams.2020.03.007
DP  - Ovid Technologies
J2  - J Sci Med Sport
KW  - Child
KW  - Child, Preschool
KW  - *Executive Function/ph [Physiology]
KW  - *Exercise/ph [Physiology]
KW  - Humans
L1  - internal-pdf://2835002980/Li-2020.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Li, LongkaiZhang, JinmingCao, MengHu, WenwenZhou, TangHuang, TaoChen, PeijieQuan, MinghuiS1440-2440(19)31332-5
PY  - 2020
SP  - 949-954
T2  - Journal of Science &amp; Medicine in Sport
TI  - The effects of chronic physical activity interventions on executive functions in children aged 3-7 years: A meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=32360243
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32360243&amp;id=doi:10.1016%2Fj.jsams.2020.03.007&amp;issn=1878-1861&amp;isbn=&amp;volume=23&amp;issue=10&amp;spage=949&amp;pages=949-954&amp;date=2020&amp;title=Journal+of+Science+%26+Medicine+in+Sport&amp;atitle=The+effects+of+chronic+physical+activity+interventions+on+executive+functions+in+children+aged+3-7+years%3A+A+meta-analysis.&amp;aulast=Li&amp;pid=%3Cauthor%3ELi+L%3C%2Fauthor%3E%3CAN%3E32360243%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.jsams.org/article/S1440-2440(19)31332-5/fulltext
VL  - 23
ER  -
TY  - JOUR
AB  - CONTEXT: Adolescents with problematic substance use (SU) are at risk for far-reaching adverse outcomes.

OBJECTIVE: Synthesize the evidence regarding the effects of brief behavioral interventions for adolescents (12-20 years) with problematic SU.

DATA SOURCES: We conducted literature searches in Medline, the Cochrane Central Register of Controlled Trials, Embase, Cumulative Index to Nursing and Allied Health Literature, and PsycInfo through October 31, 2019.

STUDY SELECTION: We screened 33 272 records and citations for interventions in adolescents with at least problematic SU, retrieved 1831 articles, and selected 22 randomized controlled trials of brief interventions meeting eligibility criteria for meta-analysis.

DATA EXTRACTION: We followed Agency for Healthcare Research and Quality guidelines. We categorized brief interventions into components, including motivational interviewing (MI), psychoeducation, and treatment as usual. Outcomes included SU (abstinence, days used per month) for alcohol and cannabis, and substance-related problem scales. Strength of evidence (SoE) was assessed.RESULTS: Both pairwise and network meta-analyses were conducted by using random effects models. Compared to treatment as usual, the use of MI reduces heavy alcohol use days by 0.7 days per month (95% credible interval [CrI]: -1.6 to 0.02; low SoE), alcohol use days by 1.1 days per month (95% CrI -2.2 to -0.3; moderate SoE), and overall substance-related problems by a standardized net mean difference of 0.5 (95% CrI -1.0 to 0; low SoE). The use of MI did not reduce cannabis use days, with a net mean difference of -0.05 days per month (95% CrI: -0.26 to 0.14; moderate SoE).

LIMITATIONS: There was lack of consistently reported outcomes and limited available comparisons.

CONCLUSIONS: The use of MI reduces heavy alcohol use, alcohol use days, and SU-related problems in adolescents but does not reduce cannabis use days.
AD  - Steele, Dale W. Evidence-based Practice Center, Center for Evidence Synthesis in Health and dale_steele@brown.edu.Steele, Dale W. Departments of Health Services, Policy, and Practice and.Steele, Dale W. Departments of Emergency Medicine.Steele, Dale W. Pediatrics, and.Becker, Sara J. Behavioral and Social Sciences, School of Public Health and.Becker, Sara J. Psychiatry and Human Behavior, Warren Alpert Medical School, Brown University, Providence, Rhode Island.Danko, Kristin J. Evidence-based Practice Center, Center for Evidence Synthesis in Health and.Danko, Kristin J. Departments of Health Services, Policy, and Practice and.Balk, Ethan M. Evidence-based Practice Center, Center for Evidence Synthesis in Health and.Balk, Ethan M. Departments of Health Services, Policy, and Practice and.Adam, Gaelen P. Evidence-based Practice Center, Center for Evidence Synthesis in Health and.Adam, Gaelen P. Departments of Health Services, Policy, and Practice and.Saldanha, Ian J. Evidence-based Practice Center, Center for Evidence Synthesis in Health and.Saldanha, Ian J. Departments of Health Services, Policy, and Practice and.Trikalinos, Thomas A. Evidence-based Practice Center, Center for Evidence Synthesis in Health and.Trikalinos, Thomas A. Departments of Health Services, Policy, and Practice and.
AN  - 32928988
AU  - Steele,
AU  - D.
AU  - W.
AU  - Becker,
AU  - S.
AU  - J.
AU  - Danko,
AU  - K.
AU  - J.
AU  - Balk,
AU  - E.
AU  - M.
AU  - Adam,
AU  - G.
AU  - P.
AU  - Saldanha,
AU  - I.
AU  - J.
AU  - Trikalinos,
AU  - T.
AU  - A.
DA  - Sep 14
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1542/peds.2020-0351
DP  - Ovid Technologies
J2  - Pediatrics
L1  - internal-pdf://4268710185/Steele-2020-Brief Behavioral Interventions for.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingSepSteele, Dale WBecker, Sara JDanko, Kristin JBalk, Ethan MAdam, Gaelen PSaldanha, Ian JTrikalinos, Thomas Ae20200351
PY  - 2020
SP  - 14
T2  - Pediatrics
TI  - Brief Behavioral Interventions for Substance Use in Adolescents: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32928988
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32928988&amp;id=doi:10.1542%2Fpeds.2020-0351&amp;issn=0031-4005&amp;isbn=&amp;volume=&amp;issue=&amp;spage=e20200351&amp;pages=&amp;date=2020&amp;title=Pediatrics&amp;atitle=Brief+Behavioral+Interventions+for+Substance+Use+in+Adolescents%3A+A+Meta-analysis.&amp;aulast=Steele&amp;pid=%3Cauthor%3ESteele+DW%3C%2Fauthor%3E%3CAN%3E32928988%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pediatrics.aappublications.org/content/pediatrics/146/4/e20200351.full.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Research has indicated beneficial effects of Animal-Assisted Interventions (AAIs) for children with Autism. However, there is a dearth of meta-analyses and findings are often contradictory. The current meta-analysis assesses the effectiveness of AAIs on social interaction, communication and global Autism symptoms. A total of 1447 studies were returned, of which 16 (n = 489) met the inclusion criteria. The meta-analyses indicated small effect sizes related to improvements in social interaction and communication and reduction in Autism Spectrum Disorder symptoms. Additionally, there was little evidence for a relationship between dosage and effect size. In conclusion, AAIs appear to offer small improvements in social interaction and communication for children with Autism, which may be comparable to activities used in active control conditions. Copyright &copy; 2020, Springer Science+Business Media, LLC, part of Springer Nature.
AD  - (Dimolareva, Dunn) Psychology Division, Bishop Grosseteste University, Lincoln, Lincolnshire LN1 3DY, United KingdomM. Dimolareva, Psychology Division, Bishop Grosseteste University, Lincoln, Lincolnshire LN1 3DY, United Kingdom. E-mail: mirena.dimolareva@bishopg.ac.uk
AN  - 2006828367
AU  - Dimolareva,
AU  - M.
AU  - Dunn,
AU  - T.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10803-020-04715-w
DP  - Ovid Technologies
KW  - Animal-assisted interventions
KW  - Autism
KW  - Children
KW  - School-age
KW  - article
KW  - child
KW  - comparative effectiveness
KW  - controlled study
KW  - effect size
KW  - female
KW  - human
KW  - male
KW  - meta analysis
KW  - social interaction
KW  - systematic review
L1  - internal-pdf://1884004515/Dimolareva-2020.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - Journal of Autism and Developmental Disorders.
TI  - Animal-Assisted Interventions for School-Aged Children with Autism Spectrum Disorder: A Meta-Analysis
UR  - http://www.wkap.nl/journalhome.htm/0162-3257
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2006828367
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:32990899&amp;id=doi:10.1007%2Fs10803-020-04715-w&amp;issn=0162-3257&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Journal+of+Autism+and+Developmental+Disorders&amp;atitle=Animal-Assisted+Interventions+for+School-Aged+Children+with+Autism+Spectrum+Disorder%3A+A+Meta-Analysis&amp;aulast=Dimolareva&amp;pid=%3Cauthor%3EDimolareva+M.%3C%2Fauthor%3E%3CAN%3E2006828367%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10803-020-04715-w
UR  - https://link.springer.com/content/pdf/10.1007/s10803-020-04715-w.pdf
ER  -
TY  - JOUR
AB  - A recent increase in the development of online parent programs calls for the need to understand how effective these strategies are for improving children&#039;s mental health. We meta-analyzed the effects of online parent programs on children&#039;s behavioral problems. Moreover, we explored the combinations of program components to yield stronger program effects. Medline, PsycINFO, Web of Science, and the Cochrane Library were searched. We included peer-reviewed randomized studies evaluating the effect of an online parent program. Effect sizes (Hedges&#039; g) were calculated from post intervention means and standard deviations. We used Qualitative Comparative Analysis (QCA) to identify pathways to effectiveness and individual content and delivery components that seem sufficient or necessary for yielding high effectiveness. Of 2941 articles, 12 articles with a total of 2025 participants met the inclusion criteria. Online parent programs have significant effects on children&#039;s behavioral problems (g = - 0.32; 95% CI, - 0.47 to - 0.17), emotional problems (g = - 0.22; 95% CI, - 0.31 to - 0.13), and parental mental health problems (g = - 0.30; 95% CI, - 0.42 to - 0.17). In the QCA, sending parents reminders to work on the program was the only one sufficient component. In conclusion, online support programs reduce children&#039;s behavioral and emotional problems and improve parental mental health. Sending parents reminders to work on the program seems to contribute to high effectiveness. Review Registration This study was registered with PROSPERO, number CRD42017080051.
AD  - Thongseiratch, Therdpong. Child Development Unit, Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand. ttherd@gmail.com.Thongseiratch, Therdpong. Research Institute of Child Development and Education, University of Amsterdam, Amsterdam, The Netherlands. ttherd@gmail.com.Leijten, Patty. Research Institute of Child Development and Education &amp; Research Priority Area YIELD, University of Amsterdam, Amsterdam, The Netherlands.Melendez-Torres, G J. The Centre for the Development and Evaluation of Complex Interventions for Public Health Improvement (DECIPHer), Cardiff University, Cardiff, UK.
AN  - 31925545
AU  - Thongseiratch,
AU  - T.
AU  - Leijten,
AU  - P.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
DA  - Nov
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-020-01472-0
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
L1  - internal-pdf://3239089123/Thongseiratch-2020.pdf
LA  - English
N1  - Thongseiratch, TherdpongLeijten, PattyMelendez-Torres, G J
PY  - 2020
SP  - 1555-1568
T2  - European Child &amp; Adolescent Psychiatry
TI  - Online parent programs for children&#039;s behavioral problems: a meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31925545
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31925545&amp;id=doi:10.1007%2Fs00787-020-01472-0&amp;issn=1018-8827&amp;isbn=&amp;volume=29&amp;issue=11&amp;spage=1555&amp;pages=1555-1568&amp;date=2020&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=Online+parent+programs+for+children%27s+behavioral+problems%3A+a+meta-analytic+review.&amp;aulast=Thongseiratch&amp;pid=%3Cauthor%3EThongseiratch+T%3C%2Fauthor%3E%3CAN%3E31925545%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs00787-020-01472-0
UR  - https://link.springer.com/content/pdf/10.1007/s00787-020-01472-0.pdf
VL  - 29
ER  -
TY  - JOUR
AB  - This study reviews the literature on reading instruction consistent with the recommendations of the National Reading Panel (NRP; National Institute of Child Health and Human Development, 2000) for children with autism spectrum disorder, using the Evaluative Method for Determining Evidence-Based Practices in Autism to assess research quality (Reichow, Volkmar, &amp; Cicchetti, 2008). A search of the literature published between 2009 and 2017 identified 10,779 relevant records, of which 19 met inclusion criteria. Studies reported gains in phonics, reading accuracy, reading fluency, and/or reading comprehension skills; however, few were of adequate or strong quality. Instruction that incorporated multiple Big Five elements from the NRP was associated with gains in reading accuracy and comprehension as well as relatively high quality ratings. Clinical implications and priorities for future research are discussed.
AN  - WOS:000533787800002
AU  - Bailey,
AU  - B.
AU  - Arciuli,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40489-019-00185-8
L1  - internal-pdf://2357006881/Bailey-2020.pdf
N1  - Bailey, Benjamin Arciuli, JoanneBailey, Benjamin/0000-0003-0086-9999; Arciuli, Joanne/0000-0002-7467-99392195-7185
PY  - 2020
SP  - 127-150
T2  - Review Journal of Autism and Developmental Disorders
TI  - Reading Instruction for Children with Autism Spectrum Disorders: A Systematic Review and Quality Analysis
UR  - &lt;Go to ISI&gt;://WOS:000533787800002
UR  - https://link.springer.com/article/10.1007%2Fs40489-019-00185-8
UR  - https://link.springer.com/content/pdf/10.1007/s40489-019-00185-8.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - The purpose of this article is to systematically review the existing literature regarding intervention and prevention programs that ameliorate the negative effects of exposure to community violence (ECV) on children and adolescents. Using the Preferred Reporting Items for Systematic Review (PRISMA) Guidelines, we conducted a systematic review of the literature aimed at providing a synthesis of the extant Randomized Control Trials (RCT) and peer-reviewed empirical literature on intervention and prevention programs for those affected by ECV. Nine randomized controlled trials were identified: seven studies with elementary school students in the USA, one study with elementary school students in Colombia, and one study with middle school students in the USA. Most trials compared intervention and no-treatment control groups; three studies compared active interventions. The intervention and prevention trials conducted in school settings in the USA showed most impact on reducing internalizing and PTSD symptoms. The evidence base of intervention and prevention programs for child and adolescent exposure to community violence is very limited. This systematic review synthesizes extant evidence of the effectiveness of intervention programs in reducing internalizing and externalizing symptoms, PTSD, exposure to community violence, and in enhancing academic performance. More studies are needed to provide a better understanding of how interventions might ameliorate the adverse consequences of exposure to community violence.
AD  - Ali-Saleh Darawshy, Neveen. Department of Family Social Science &amp; Institute of Translational Research in Children&#039;s Mental Health, University of Minnesota, Minneapolis, USA. Nevosh78@gmail.com.Gewirtz, Abigail. Department of Family Social Science &amp; Institute of Translational Research in Children&#039;s Mental Health, University of Minnesota, Minneapolis, USA.Marsalis, Scott. Department of Family Social Science &amp; Institute of Translational Research in Children&#039;s Mental Health, University of Minnesota, Minneapolis, USA.
AN  - 32215777
AU  - Ali-Saleh
AU  - Darawshy,
AU  - N.
AU  - Gewirtz,
AU  - A.
AU  - Marsalis,
AU  - S.
DA  - Mar 25
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-020-00315-3
DP  - Ovid Technologies
J2  - Clin Child Fam Psychol Rev
L1  - internal-pdf://0083736741/Ali-Saleh Darawshy-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingMarAli-Saleh Darawshy, NeveenGewirtz, AbigailMarsalis, Scott
PY  - 2020
SP  - 25
T2  - Clinical Child &amp; Family Psychology Review
TI  - Psychological Intervention and Prevention Programs for Child and Adolescent Exposure to Community Violence: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32215777
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32215777&amp;id=doi:10.1007%2Fs10567-020-00315-3&amp;issn=1096-4037&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Clinical+Child+%26+Family+Psychology+Review&amp;atitle=Psychological+Intervention+and+Prevention+Programs+for+Child+and+Adolescent+Exposure+to+Community+Violence%3A+A+Systematic+Review.&amp;aulast=Ali-Saleh+Darawshy&amp;pid=%3Cauthor%3EAli-Saleh+Darawshy+N%3C%2Fauthor%3E%3CAN%3E32215777%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s10567-020-00315-3
UR  - https://link.springer.com/content/pdf/10.1007/s10567-020-00315-3.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - **Background**
Around 1 in 1000 adolescents aged 12 to 17 years old display problematic or harmful sexual behaviour (HSB). Examples include behaviours occurring more frequently than would be considered developmentally appropriate; accompanied by coercion; involving children of different ages or stages of development; or associated with emotional distress. Some, but not all, young people engaging in HSB come to the attention of authorities for investigation, prosecution or treatment. Depending on policy context, young people with HSB are those whose behaviour has resulted in a formal reprimand or warning, conviction for a sexual offence, or civil measures. Cognitive‐behavioural therapy (CBT) interventions are based on the idea that by changing the way a person thinks, and helping them to develop new coping skills, it is possible to change behaviour.

**Objectives**
To evaluate the effects of CBT for young people aged 10 to 18 years who have exhibited HSB.

**Search methods**
In June 2019, we searched CENTRAL, MEDLINE, Embase, 12 other databases and three trials registers. We also examined relevant websites, checked reference lists and contacted authors of relevant articles.

**Selection criteria**
We included all relevant randomised controlled trials (RCTs) using parallel groups. We evaluated CBT treatments compared with no treatment, waiting list or standard care, irrespective of mode of delivery or setting, given to young people aged 10 to 18 years, who had been convicted of a sexual offence or who exhibited HSB.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane.

**Main results**
We found four eligible RCTs (115 participants). Participants in two studies were adolescent males aged 12 to 18 years old. In two studies participants were males simply described as &quot;adolescents.&quot;

Three studies took place in the USA and one in South Africa. The four studies were of short duration: one lasted two months; two lasted three months; and one lasted six months. No information was available on funding sources.

Two studies compared group‐based CBT respectively to no treatment (18 participants) or treatment as usual (21 participants). The third compared CBT with sexual education (16 participants). The fourth compared CBT (19 participants) with mode‐deactivation therapy (21 participants) and social skills training (20 participants). Three interventions delivered treatment in a residential setting by someone working there, and one in a community setting by licensed therapist undertaking a PhD.

CBT compared with no treatment or treatment as usual

Primary outcomes

No study in this comparison reported the impact of CBT on any measure of primary outcomes (recidivism, and adverse events such as self‐harm or suicidal behaviour).

Secondary outcomes

There was little to no difference between CBT and treatment as usual on cognitive distortions in general (mean difference (MD) 1.56, 95% confidence interval (CI) ‐11.54 to 14.66, 1 study, 18 participants; very low‐certainty evidence), assessed with Abel and Becker Cognition Scale (higher scores indicate more problematic distortions); and specific cognitive distortions about rape (MD 8.75, 95% CI 2.83 to 14.67, 1 study, 21 participants; very low‐certainty evidence), measured with the Bumby Cardsort Rape Scale (higher scores indicate more justifications, minimisations, rationalisations and excuses for HSB).

One study (18 participants) reported very low‐certainty evidence that CBT may result in greater improvements in victim empathy (MD 5.56, 95% CI 0.94 to 10.18), measured with the Attitudes Towards Women Scale, compared with no treatment. One additional study also measured this, but provided no usable data.

CBT compared with alternative interventions

Primary outcomes

One study (59 participants) found little to no difference between CBT and alternative treatments on post‐treatment sexual aggression scores (MD 0.09, 95% CI ‐0.18 to 0.37, very low‐certainty evidence), assessed using Daily Behaviour Reports and Behaviour Incidence Report Forms. No study in this comparison reported the impact of CBT on any measure of our remaining primary outcomes.

Secondary outcomes
One study (16 participants) provided very low‐certainty evidence that, compared to sexual education, mean cognitive distortions pertaining to justification or taking responsibility for actions (MD 3.27, 95% CI
AU  - Sneddon,
AU  - H.
AU  - Gojkovic
AU  - Grimshaw,
AU  - D.
AU  - Livingstone,
AU  - N.
AU  - Macdonald,
AU  - G.
DA  - 23 june
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD009829.pub2
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive‐behavioural therapy (CBT) interventions for young people aged 10 to 18 with harmful sexual behaviour
ER  -
TY  - JOUR
AB  - **Background:** A noticeable proportion of adolescents with depression do not respond to guideline recommended treatment options. This systematic review and meta-analysis investigated the effectiveness of physical activity interventions as an alternative or complementary treatment for adolescents (12&ndash;18 years) with depression. The characteristics of the physical activity treatment that were most effective in reducing symptoms in adolescents with depression and the impact of methodological shortcomings in the existing research were also examined.

**Methods:** Medline, PsycINFO, SPORTDiscus, ProQuest, and CENTRAL were searched for eligible records. Effect size estimates were pooled based on the application of a random-effects model. Potential moderation by physical activity characteristics (i.e., intensity, type, context, and time frame) and methodological features (i.e., type of control group and diagnostic tool to identify depression at baseline) was investigated by means of subgroup analyses and meta-regressions. The certainty of evidence was assessed by the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. The primary outcome was the antidepressant effect of physical activity at postintervention measurement time point. As secondary outcomes, the sustainability of effects after the end of physical activity treatment and the acceptability of physical activity treatments were assessed. Overall, 10 studies were included in the qualitative synthesis and 9 studies involving 431 patients were included in the quantitative synthesis.

**Results:** A moderate, significant antidepressant effect of physical activity was found (Hedges&#039; g = &minus;0.47, 95% CI = &minus;0.71 to &minus;0.24). Heterogeneity was small (T2 = 0.0313, I2 = 27%, p = 0.18). However, the certainty of evidence was downgraded to low because the included studies contained serious methodological limitations. Moderator analyses revealed that session intensity significantly moderated the antidepressant effect of physical activity. Moreover, noticeably smaller effect sizes were found in studies that used non-physical activity sham treatments as control treatments (e.g., playing board games), compared to studies that used no control group treatments. Only three studies assessed the sustainability of effects after the end of physical activity treatment. The results suggest that the antidepressant effects further increase after the end of physical activity interventions. There was no significant difference in dropout risk between the physical activity and control groups.

**Conclusions:** This review suggests that physical activity is effective in treating depression in adolescents. Physical activity sessions should be at least moderately intense [rate of perceived exertion (RPE) between 11 and 13] to be effective. Furthermore, our results suggest that physical activity treatments are well accepted. However, the low methodological quality in included studies might have led to effect overestimation. Therefore, more studies with higher methodological quality are needed to confirm the recommendation for physical activity treatments in adolescents with depression.
AD  - Oberste, Max. Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.Medele, Marie. Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, University of Cologne, Cologne, Germany.Javelle, Florian. Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.Lioba Wunram, Heidrun. Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, University of Cologne, Cologne, Germany.Lioba Wunram, Heidrun. Children&#039;s Hospital, Medical Faculty, University of Cologne, Cologne, Germany.Walter, Daniel. Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, University of Cologne, Cologne, Germany.Walter, Daniel. School of Child and Adolescent Cognitive Behavior Therapy (AKiP) at the University Hospital Cologne, Cologne, Germany.Bloch, Wilhelm. Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.Bender, Stephan. Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty, University of Cologne, Cologne, Germany.Fricke, Oliver. Chair of Child and Adolescent Psychiatry, Witten/Herdecke University, Department of Child and Adolescent Psychiatry, Psychotherapy and Child Neurology, Gemeinschaftskrankenhaus Herdecke, Herdecke, Germany.Joisten, Niklas. Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.Walzik, David. Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.Grosheinrich, Nicola. Department of Social Sciences, Catholic University of Applied Science of North Rhine - Westphalia, Cologne, Germany.Zimmer, Philipp. Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sports Medicine, German Sport University Cologne, Cologne, Germany.Zimmer, Philipp. Department of &quot;Performance and Health (Sports Medicine)&quot;, Institute of Sport and Sport Science, Technical University Dortmund, Dortmund, Germany.
AN  - 32265725
AU  - Oberste,
AU  - M.
AU  - Medele,
AU  - M.
AU  - Javelle,
AU  - F.
AU  - Lioba
AU  - Wunram,
AU  - H.
AU  - Walter,
AU  - D.
AU  - Bloch,
AU  - W.
AU  - Bender,
AU  - S.
AU  - Fricke,
AU  - O.
AU  - Joisten,
AU  - N.
AU  - Walzik,
AU  - D.
AU  - Grosheinrich,
AU  - N.
AU  - Zimmer,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fphys.2020.00185
DP  - Ovid Technologies
J2  - Front Physiol
L1  - internal-pdf://2693971804/Oberste-2020-Physical Activity for the Treatme.pdf
LA  - English
M3  - Systematic Review
N1  - Oberste, MaxMedele, MarieJavelle, FlorianLioba Wunram, HeidrunWalter, DanielBloch, WilhelmBender, StephanFricke, OliverJoisten, NiklasWalzik, DavidGrosheinrich, NicolaZimmer, Philipp
PY  - 2020
SP  - 185
T2  - Frontiers in Physiology
TI  - Physical Activity for the Treatment of Adolescent Depression: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32265725
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096373/pdf/fphys-11-00185.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Objectives:** 
To examine and analyse the intervention effects of the Early Start Denver Model (ESDM) on children with autism spectrum disorder (ASD). 

**Method(s):** 
This meta-analysis evaluated the effect sizes in four major domains of measurement (autism symptoms, language, cognition, and social communication). A total of 624 participants with ASD were included in 11 high-quality randomized controlled trial studies. 

**Result(s):** 
The results indicated that the ESDM intervention resulted in significant improvement with moderate effect sizes in the cognition (g = 0.28), autism symptoms (g = 0.27), and language (g = 0.29) domains. The effect sizes of autism symptoms and language were moderated by country (Western versus Asian countries). However, there were no significant effects observed for the social communication domain. 

**Conclusion(s):** 
The ESDM intervention significantly improved autism symptoms, language, and cognition. The effect sizes of autism symptoms and language were larger in Asian countries than in Western countries. Copyright &copy; The British Society of Developmental Disabilities 2021.
AD  - (Wang, Loh) Faculty of Education, University of Malaya, Kuala Lumpur, Malaysia (Tian) School of Education, Guizhou Education University, Guiyang City, Guizhou Province, China (Chen) School of Management, Guizhou University, Guiyang City, Guizhou Province, ChinaZ. Wang, Faculty of Education, University of Malaya, Jalan Universiti, Kuala Lumpur 50603, Malaysia. E-mail: 17221470@siswa.um.edu.my
AN  - 2010147111
AU  - Wang,
AU  - Z.
AU  - Loh,
AU  - S.
AU  - C.
AU  - Tian,
AU  - J.
AU  - Chen,
AU  - Q.
AU  - J.
DA  - Januar
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/20473869.2020.1870419
DP  - Ovid Technologies
KW  - autism spectrum disorder
KW  - Early Start Denver Model
KW  - meta-analysis
KW  - randomized controlled trials
KW  - autism
KW  - child
KW  - cognition
KW  - controlled study
KW  - effect size
KW  - female
KW  - human
KW  - language
KW  - male
KW  - meta analysis
KW  - randomized controlled trial (topic)
KW  - review
L1  - internal-pdf://2648486129/Wang-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - International Journal of Developmental Disabilities.
TI  - A meta-analysis of the effect of the Early Start Denver Model in children with autism spectrum disorder
UR  - http://www.tandfonline.com/loi/yjdd20#.VwHmUE1f1Qs
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010147111
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1080%2F20473869.2020.1870419&amp;issn=2047-3869&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=International+Journal+of+Developmental+Disabilities&amp;atitle=A+meta-analysis+of+the+effect+of+the+Early+Start+Denver+Model+in+children+with+autism+spectrum+disorder&amp;aulast=Wang&amp;pid=%3Cauthor%3EWang+Z.%3C%2Fauthor%3E%3CAN%3E2010147111%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/full/10.1080/20473869.2020.1870419
UR  - https://www.tandfonline.com/doi/pdf/10.1080/20473869.2020.1870419?needAccess=true
ER  -
TY  - JOUR
AB  - BACKGROUND: The prevalence of chronic health conditions in childhood is increasing, and behavioral interventions can support the management of these conditions. Compared with face-to-face treatment, the use of digital interventions may be more cost-effective, appealing, and accessible, but there has been inadequate attention to their use with younger populations (children aged 5-12 years).

OBJECTIVE: This systematic review aims to (1) identify effective digital interventions, (2) report the characteristics of promising interventions, and (3) describe the user&#039;s experience of the digital intervention.

METHODS: A total of 4 databases were searched (Excerpta Medica Database [EMBASE], PsycINFO, Medical Literature Analysis and Retrieval System Online [MEDLINE], and the Cochrane Library) between January 2014 and January 2019. The inclusion criteria for studies were as follows: (1) children aged between 5 and 12 years, (2) interventions for behavior change, (3) randomized controlled trials, (4) digital interventions, and (5) chronic health conditions. Two researchers independently double reviewed papers to assess eligibility, extract data, and assess quality.

RESULTS: Searches run in the databases identified 2643 papers. We identified 17 eligible interventions. The most promising interventions (having a beneficial effect and low risk of bias) were 3 targeting overweight or obesity, using exergaming or social media, and 2 for anxiety, using web-based cognitive behavioral therapy (CBT). Characteristics of promising interventions included gaming features, therapist support, and parental involvement. Most were purely behavioral interventions (rather than CBT or third wave), typically using the behavior change techniques (BCTs) feedback and monitoring, shaping knowledge, repetition and substitution, and reward. Three papers included qualitative data on the user&#039;s experience. We developed the following themes: parental involvement, connection with a health professional is important for engagement, technological affordances and barriers, and child-centered design.

CONCLUSIONS: Of the 17 eligible interventions, digital interventions for anxiety and overweight or obesity had the greatest promise. Using qualitative methods during digital intervention development and evaluation may lead to more meaningful, usable, feasible, and engaging interventions, especially for this underresearched younger population. The following characteristics could be considered when developing digital interventions for younger children: involvement of parents, gaming features, additional therapist support, behavioral (rather than cognitive) approaches, and particular BCTs (feedback and monitoring, shaping knowledge, repetition and substitution, and reward). This review suggests a model for improving the conceptualization and reporting of behavioral interventions involving children and parents.
AD  - Brigden, Amberly. Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, United Kingdom.Anderson, Emma. Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, United Kingdom.Linney, Catherine. Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, United Kingdom.Morris, Richard. Bristol Medical School, University of Bristol, Bristol, United Kingdom.Parslow, Roxanne. Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, United Kingdom.Serafimova, Teona. Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, United Kingdom.Smith, Lucie. Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, United Kingdom.Briggs, Emily. Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, United Kingdom.Loades, Maria. Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, United Kingdom.Loades, Maria. Department of Psychology, University of Bath, Bath, United Kingdom.Crawley, Esther. Centre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
AN  - 32735227
AU  - Brigden,
AU  - A.
AU  - Anderson,
AU  - E.
AU  - Linney,
AU  - C.
AU  - Morris,
AU  - R.
AU  - Parslow,
AU  - R.
AU  - Serafimova,
AU  - T.
AU  - Smith,
AU  - L.
AU  - Briggs,
AU  - E.
AU  - Loades,
AU  - M.
AU  - Crawley,
AU  - E.
DA  - Jul 31
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/16924
DP  - Ovid Technologies
J2  - J Med Internet Res
L1  - internal-pdf://1086203066/Bridgen.pdf
LA  - English
M3  - Review
N1  - Brigden, AmberlyAnderson, EmmaLinney, CatherineMorris, RichardParslow, RoxanneSerafimova, TeonaSmith, LucieBriggs, EmilyLoades, MariaCrawley, Esther
PY  - 2020
SP  - e16924
T2  - Journal of Medical Internet Research
TI  - Digital Behavior Change Interventions for Younger Children With Chronic Health Conditions: Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32735227
VL  - 22
ER  -
TY  - JOUR
AB  - **Background**
Enuresis (bedwetting) affects up to 20% of five‐year‐olds and can have considerable social, emotional and psychological effects. Treatments include alarms (activated by urination), behavioural interventions and drugs.

**Objectives**
To assess the effects of enuresis alarms for treating enuresis in children.

**Search methods**
We searched the Cochrane Incontinence Specialised Register, which contains trials identified from the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, MEDLINE In‐Process, MEDLINE Epub Ahead of Print, ClinicalTrials.gov, WHO ICTRP, and handsearching of journals and conference proceedings (searched 25 June 2018), and reference lists of relevant articles.

**Selection criteria**
We included randomised or quasi‐randomised trials of enuresis alarms or alarms combined with another intervention for treating nocturnal enuresis in children between 5 and 16 years old.

**Data collection and analysis**
Two review authors independently assessed risk of bias and extracted data.

**Main results**
We included 74 trials (5983 children).

At treatment completion, alarms may reduce the number of wet nights a week compared to control or no treatment (mean difference (MD) &minus;2.68, 95% confidence interval (CI) &minus;4.59 to &minus;0.78; 4 trials, 127 children; low‐quality evidence). Low‐quality evidence suggests more children may achieve complete response (14 consecutive dry nights) with alarms compared to control or no treatment (RR 7.23, 95% CI 1.40 to 37.33; 18 trials, 827 children) and that more children may remain dry post‐treatment (RR 9.67, 95% CI 4.74 to 19.76; 10 trials, 366 children; low‐quality evidence).

At treatment completion, we are uncertain whether there is any difference between alarms and placebo drugs in the number of wet nights a week (MD &minus;0.96, 95% CI &minus;2.32 to 0.41; 1 trial, 47 children; very low‐quality evidence). Alarms may result in more children achieving complete response than with placebo drugs (RR 1.59, 95% CI 1.16 to 2.17; 2 trials, 181 children; low‐quality evidence). No trials comparing alarms to placebo reported the number of children remaining dry post‐treatment.

Compared with control alarms, code‐word alarms probably slightly increase the number of children achieving complete response at treatment completion (RR 1.11, 95% CI 0.97 to 1.27; 1 trial, 353 children; moderate‐quality evidence) but there is probably little to no difference in the number of children remaining dry post‐treatment (RR 0.91, 95% CI 0.79 to 1.05; moderate‐quality evidence). Very low‐quality evidence means we are uncertain if there are any differences in effectiveness between the other different types of alarm.

At treatment completion, alarms may reduce the number of wet nights a week compared with behavioural interventions (waking, bladder training, dry‐bed training, and star chart plus rewards) (MD ‐0.81, 95% CI ‐2.01 to 0.38; low‐quality evidence) and may increase the number of children achieving complete response (RR 1.77, 95% CI 0.98 to 3.19; low‐quality evidence) and may slightly increase the number of children remaining dry post‐treatment (RR 1.39, 95% CI 0.81 to 2.41; low‐quality evidence).The evidence relating to alarms compared with desmopressin in the number of wet nights a week (MD &minus;0.64, 95% CI &minus;1.77 to 0.49; 4 trials, 285 children) and the number of children achieving complete response at treatment completion (RR 1.12, 95% CI 0.93 to 1.36; 12 trials, 1168 children) is low‐quality, spanning possible harms and possible benefits. Alarms probably slightly increase the number of children remaining dry post‐treatment compared with desmopressin (RR 1.30, 95% CI 0.92 to 1.84; 5 trials, 565 children; moderate‐quality evidence).

At treatment completion, we are uncertain if there is any difference between alarms and tricyclics in the number of wet nights a week, the number of children achieving complete response or the number of children remaining dry post‐treatment, because the quality of evidence is very low.

Due to very low‐quality evidence we are uncertain about any differences in effectiveness between alarms and cognitive behavioural therapy, psychotherapy, hypnotherapy and restricted diet.

Alarm plus desmopressin may reduce the number of wet nights a week compared with desmopressin monotherapy (MD &minus;0.88, 95% CI &minus;0.38 to &minus;1.38; 2 trials, 156 children; low‐quality evidence). Alarm plus desmopressin may increase the number of children achieving complete response (RR 1.32, 95% CI 1.08 to 1.62; 5 trials, 359 children; low‐quality evidence) and the number of children remaining dry post‐treatment (RR 2.33, 95% CI 1.26 to 4.29; 2 trials, 161 children; low‐quality evidence) compared with desmopressin alone.

Alarm plus dry‐bed training may increase the number of children achieving a complete response compared to dry‐bed training alone (RR 3.79, 95% CI 1.85 to 7.77; 1 trial, 80 children; low‐quality evidence). It is unclear if there is any difference in the number of children remaining dry post‐treatment because of the wide confidence interval (RR 0.56, 95% CI 0.15 to 2.12; low‐quality evidence). Due to very low‐quality evidence, we are uncertain about any differences in effectiveness between alarm plus bladder training versus bladder training alone.

Of the 74 included trials, 17 reported one or more adverse events, nine reported no adverse events and 48 did not mention adverse events. Adverse events attributed to alarms included failure to wake the child, ringing without urination, waking others, causing discomfort, frightening the child and being too difficult to use. Adverse events of comparator interventions included nose bleeds, headaches and abdominal pain.

There is probably a slight increase in adverse events between code‐word alarm and standard alarm (RR 1.34, 95% CI 0.75 to 2.38; moderate‐quality evidence), although we are uncertain because of the wide confidence interval. Alarms probably reduce the number of children experiencing adverse events compared with desmopressin (RR 0.38, 95% CI 0.20 to 0.71; 5 trials, 565 children; moderate‐quality evidence). Very low‐quality evidence means we cannot be certain whether the adverse event rate for alarms is lower than for other treatments.

**Authors&#039; conclusions**
Alarm therapy may be more effective than no treatment in reducing enuresis in children. We are uncertain if alarm therapy is more effective than desmopressin but there is probably a lower risk of adverse events with alarms than with desmopressin. Despite the large number of trials included in this review, further adequately‐powered trials with robust randomisation are still needed to determine the full effect of alarm therapy.
AU  - Caldwell,
AU  - P.
AU  - Codarini,
AU  - M.
AU  - Stewart,
AU  - F.
AU  - Hahn,
AU  - D.
AU  - Sureshkumar,
AU  - P.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD002911.pub3
L1  - internal-pdf://1854973875/Caldwell_et_al-2020-Cochrane_Database_of_Syste.pdf
PY  - 2020
TI  - Alarm interventions for nocturnal enuresis in children
ER  -
TY  - JOUR
AB  - Since the introduction of iPads in 2010, educators have been working to effectively incorporate this technology as a supplement to curriculum and a tool to increase student engagement and student achievement. The current investigation examines the effectiveness of iPad applications in supporting the instruction of students identified on the autism spectrum. Specifically, this investigation provides a meta-analysis of available research that examines the use of iPad technology and its impact on learning outcomes for students with autism. Four studies were found that provided results for groups of students. The findings of this research are based on 12 effect-size measures, representing a synthesized sample size of 99 participants. The results suggest that the use of iPad technology can have a positive, significant effect on student learning outcomes. The moderators of these positive outcomes are presented and discussed.
AD  - [Aspiranti, Kathleen B.; Larwin, Karen H.; Schade, Benjamin P.] Youngstown State Univ, Dept Counseling, Sch Psychol &amp; Educ Leadership, One Univ Plaza, Youngstown, OH 44555 USA.Aspiranti, KB (reprint author), Youngstown State Univ, Dept Counseling, Sch Psychol &amp; Educ Leadership, One Univ Plaza, Youngstown, OH 44555 USA.kaspiranti@ysu.edu
AN  - WOS:000506052500004
AU  - Aspiranti,
AU  - K.
AU  - B.
AU  - Larwin,
AU  - K.
AU  - H.
AU  - Schade,
AU  - B.
AU  - P.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1080/10400435.2018.1463575
J2  - Assist. Technol.
KW  - developmental disability
KW  - education
KW  - emerging trends
KW  - technology-based interventions
KW  - single-case designs
KW  - spectrum disorder
KW  - developmental-disabilities
KW  - children
KW  - individuals
KW  - performance
KW  - future
KW  - power
KW  - Rehabilitation
L1  - internal-pdf://2143064225/Aspiranti-2020-iPads_tablets and students with.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: KA8KWTimes Cited: 0Cited Reference Count: 36Aspiranti, Kathleen B. Larwin, Karen H. Schade, Benjamin P.038Taylor &amp; francis incPhiladelphia1949-3614
PY  - 2020
SP  - 23-30
T2  - Assistive Technology
TI  - iPads/tablets and students with autism: A meta-analysis of academic effects
UR  - &lt;Go to ISI&gt;://WOS:000506052500004
UR  - https://www.tandfonline.com/doi/pdf/10.1080/10400435.2018.1463575?needAccess=true
VL  - 32
ER  -
TY  - JOUR
AB  - **Objectives** 
This meta-analysis examines the efficacy of programs at increasing knowledge about dating violence, changing attitudes, increasing bystander behaviors, and reducing incidents of dating violence perpetration and victimization. 

**Methods** 
A systematic search yielded 38 studies contributing 73 independent effect sizes. Studies were pooled by outcome measure and ten moderators were used to examine the impacts of program and study characteristics. 

**Results** 
Prevention programs had a significant, positive impact on measures of knowledge (ES = 0.566,z = 3.59), attitudes (ES = 0.191,z = 3.88), and violence perpetration (ES = .157,z = 3.11), but did not significantly impact experiences of victimization or bystander behaviors. 

**Conclusions** 
Results indicate that dating violence prevention programs are effective at improving knowledge, attitudes, and some behaviors, providing support for the continued implementation of these programs with adolescent populations. Future research should investigate the impact of specific program content and long-term behavioral outcomes.
AN  - WOS:000572723600001
AU  - Lee,
AU  - C.
AU  - Wong,
AU  - J.
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s11292-020-09442-x
L1  - internal-pdf://4072502139/Lee.pdf
N1  - Lee, Chelsey Wong, Jennifer S.1572-8315
PY  - 2020
T2  - Journal of Experimental Criminology
TI  - Examining the effects of teen dating violence prevention programs: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000572723600001
UR  - https://link.springer.com/article/10.1007%2Fs11292-020-09442-x
UR  - https://link.springer.com/content/pdf/10.1007/s11292-020-09442-x.pdf
ER  -
TY  - JOUR
AB  - The prevalence of post-traumatic stress disorder symptoms in children and adolescents requires school psychologists and counsellors to be informed of evidence-based elements of interventions through which they can tailor their treatment to the individual in a school context. This meta-analysis identified common practice elements within evidence-based trauma interventions for schools. A small to medium effect size was identified in the 10 randomised controlled trials (RCTs) included in this meta-analysis. Within these RCTs, 31 common practice elements were identified, with social skills training, coping skills training, relaxation techniques, psychoeducation, mind-body techniques, group work and creative-expressive techniques correlating with the most effective outcomes. The findings suggest that common practice elements exist across multiple school-based trauma interventions of varying modalities.
AN  - WOS:000587995600003
AU  - Kenyon,
AU  - G.
AU  - D.
AU  - Schirmer,
AU  - J.
DA  - Dec
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1017/jgc.2019.31
L1  - internal-pdf://3189665636/Kenyon-2020.pdf
N1  - du Mello Kenyon, Georgina Schirmer, Jim2055-6373
PY  - 2020
SP  - 112-128
T2  - Journal of Psychologists and Counsellors in Schools
TI  - Common practice elements of school-based trauma interventions for children and adolescents exhibiting symptoms of post-traumatic stress disorder: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000587995600003
UR  - https://www.cambridge.org/core/journals/journal-of-psychologists-and-counsellors-in-schools/article/abs/common-practice-elements-of-schoolbased-trauma-interventions-for-children-and-adolescents-exhibiting-symptoms-of-posttraumatic-stress-disorder-a-systematic-review/2DDA1A058B8D047F5D4BC6BFA740B1D8
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/2DDA1A058B8D047F5D4BC6BFA740B1D8/S2055636519000314a.pdf/div-class-title-common-practice-elements-of-school-based-trauma-interventions-for-children-and-adolescents-exhibiting-symptoms-of-post-traumatic-stress-disorder-a-systematic-review-div.pdf
VL  - 30
ER  -
TY  - JOUR
AB  - Children growing up in families experiencing complex and multiple problems (FECMP) are at an increased risk of developing problems in multiple areas of life. A wide array of home-visiting interventions has been developed to address the complex care needs of these families. The aim of this study is to investigate out-of-home placement rates and child outcomes of these home-visiting interventions. A systematic review and meta-analysis was conducted using five scientific databases (Psyclnfo, ERIC, Soclndex, MedLine, &amp; Picarta). The systematic search of these databases yielded 8,377 hits. Forty-two publications reporting on 50 studies were included in the review. A random-effects survival curve meta-analysis model was estimated for out-of-home placement and random-effects meta-analysis models were estimated for children&#039;s behavioral problems and stressful experiences. Out-of-home placement increased from 7.5% at case closure to 24.3% one year after case closure. On average there was a moderate decrease in emotional and behavioral problems (d = 0.50) and stressful experiences (d = 0.50) during intervention, but considerable problems remained after case closure. More research is needed to investigate family and service characteristics that may explain heterogeneity in outcomes. Furthermore, there is a need to adopt a broader perspective in evaluations of home-visiting services by including outcomes related to the skills, development, and wellbeing of children.
AN  - WOS:000538104100003
AU  - van
AU  - Assen,
AU  - A.
AU  - G.
AU  - Knot-Dickscheit,
AU  - J.
AU  - Post,
AU  - W.
AU  - J.
AU  - Grietens,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.childyouth.2020.104994
L1  - internal-pdf://2009962600/van Assen-2020.pdf
N1  - van Assen, A. G. (Arjen) Knot-Dickscheit, J. (Jana) Post, W. J. (Wendy) Grietens, H. (Hans)Post, Wendy/0000-0002-4290-62871873-7765
PY  - 2020
T2  - Children and Youth Services Review
TI  - Home-visiting interventions for families with complex and multiple problems: A systematic review and meta-analysis of out-of-home placement and child outcomes
UR  - &lt;Go to ISI&gt;://WOS:000538104100003
VL  - 114
ER  -
TY  - JOUR
AB  - **Objectives** 
Meta-analyses have identified benefits of meditation for many specific health outcomes, including depression, diabetes, and smoking. However, the meditation literature lacks a comprehensive synthesis of meta-analyses on meditation-health effects. This study used metasynthesis (i.e., second-order meta-analysis) to derive a comprehensive estimate of the effect of meditation on health. 

**Methods** 
Twenty-eight meta-analyses of randomized controlled trials, which collectively provided 404 meta-analytic effects from over 31,000 participants, met criteria for inclusion. Information on the type of health outcome, meditation, and sample as well as the methodological quality and average intervention length was extracted from each meta-analysis. An unweighted model was used to aggregate data. 

**Results** 
A medium-sized effect of meditation on health was obtained after aggregating across meta-analyses (d = 0.50, 95% CI [0.42, 0.58]). The effect of meditation was stronger when examining yoga than mindfulness or focused attention, was similar for mental and physical health, and was stronger in younger samples, higher quality studies, and studies with longer interventions. 

**Conclusions** 
This metasynthesis provides among the most compelling evidence to date that meditation benefits health. Nonetheless, current estimates of meditation-health effects may be inflated as a result of publication bias, low quality studies, and use of inactive control conditions.
AD  - [Rose, Sabrina; Zell, Ethan; Strickhouser, Jason E.] Univ N Carolina, Dept Psychol, Greensboro, NC 27412 USA. [Rose, Sabrina] Ganeshas Yoga &amp; Wellness, Greensboro, NC USA. [Strickhouser, Jason E.] Florida State Univ, Dept Behav Sci &amp; Social Med, Tallahassee, FL 32306 USA.Zell, E (reprint author), Univ N Carolina, Dept Psychol, Greensboro, NC 27412 USA.e_zell@uncg.edu
AN  - WOS:000511570700019
AU  - Rose,
AU  - S.
AU  - Zell,
AU  - E.
AU  - Strickhouser,
AU  - J.
AU  - E.
DA  - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s12671-019-01277-6
J2  - Mindfulness
KW  - Meditation
KW  - Mindfulness
KW  - Health
KW  - Well-being
KW  - Meta-analysis
KW  - mindfulness-based interventions
KW  - psychological stress
KW  - cognitive
KW  - therapy
KW  - immune-system
KW  - metaanalysis
KW  - mechanisms
KW  - acceptance
KW  - efficacy
KW  - quality
KW  - Psychology
KW  - Psychiatry
L1  - internal-pdf://0476687478/Rose-2020.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: KI7YTTimes Cited: 0Cited Reference Count: 47Rose, Sabrina Zell, Ethan Strickhouser, Jason E.Strickhouser, Jason/0000-0001-6629-862901SpringerDordrecht1868-8535Si
PY  - 2020
SP  - 507-516
T2  - Mindfulness
TI  - The Effect of Meditation on Health: a Metasynthesis of Randomized Controlled Trials
UR  - &lt;Go to ISI&gt;://WOS:000511570700019
UR  - https://link.springer.com/article/10.1007%2Fs12671-019-01277-6
VL  - 11
ER  -
TY  - JOUR
AB  - **Objective**: This multilevel meta-analysis compared the outcomes of Treatment Foster Care Oregon for Adolescents (TFCO-A) and home-based treatment programs (HBT) with residential youth care for children and youth aged 0 to 23 years. 

**Methods**: A total of 145 effect sizes for different types of behavioral problems were derived from 24 controlled studies (n = 16,943 participants). A three-level random-effects meta-analysis was conducted. 

**Results**: We found a small statistically significant overall effect (d = 0.21), 95% CI [0.090-0.338], which indicated that non-residential youth care was slightly more effective than residential youth care. However, moderator analysis revealed that TFCO-A yielded a larger effect size (d = 0.36) than HBT (d = 0.08). 

**Conclusions**: Our findings suggest that youth treated in treatment foster care have better outcomes than youth in residential care, which is not true for children who are treated at home. Therefore, in case of out-of-home placement treatment foster care should be the first option. Given that residential care has no additional value for youth who are treated at home, and often sets limits to juveniles&#039; needs for self-determination, residential care seems an option if TFCO-A is not available and living at home is no longer possible because the child&#039;s (immediate) safety is at stake. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - ZPMGutterswijk, Raymond V.: gutterswijk@essb.eur.nl; Kuiper, Chris H. Z.: kuiper.c@hsleiden.nl; van der Horst, Frank C. P.: vanderhorst@essb.eur.nl; Stams, Geert Jan J. M.: g.j.j.m.stams@uva.nl; Prinzie, Peter: prinzie@essb.eur.nlGutterswijk, Raymond V.: Horizon Youth Care and Special Education, Mozartlaan 150, Rotterdam, Netherlands, 3055 KM, gutterswijk@essb.eur.nlGutterswijk, Raymond V.: Department of Psychology, Education &amp; Child Studies, Erasmus University Rotterdam, Rotterdam, NetherlandsKuiper, Chris H. Z.: Horizon Youth Care and Special Education, Rotterdam, NetherlandsLautan, Navisha: Horizon Youth Care and Special Education, Rotterdam, NetherlandsKunst, Elsemieke G.: VU University, Amsterdam, Netherlandsvan der Horst, Frank C. P.: Department of Psychology, Education &amp; Child Studies, Erasmus University Rotterdam, Rotterdam, NetherlandsStams, Geert Jan J. M.: University of Amsterdam, Amsterdam, NetherlandsPrinzie, Peter: Department of Psychology, Education &amp; Child Studies, Erasmus University Rotterdam, Rotterdam, Netherlands
AN  - 2020-33397-001
AU  - Gutterswijk,
AU  - R.
AU  - V.
AU  - Kuiper,
AU  - C.
AU  - H.
AU  - Lautan,
AU  - N.
AU  - Kunst,
AU  - E.
AU  - G.
AU  - van
AU  - der
AU  - Horst,
AU  - F.
AU  - C.
AU  - Stams,
AU  - G.
AU  - J.
AU  - J.
AU  - Prinzie,
AU  - P.
DA  - Jun
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.childyouth.2020.104950
DP  - Ovid Technologies
KW  - Foster care treatment, Home-based treatment, Residential youth care, Meta-analysis, Behavioral problems, Effectiveness
KW  - *Foster Care
KW  - *Home Care
KW  - *Residential Care Institutions
KW  - *Treatment Outcomes
KW  - Behavior Problems
KW  - Effect Size (Statistical)
KW  - Elder Care
KW  - Home Environment
KW  - Treatment Withholding
KW  - Health &amp; Mental Health Services [3370]
KW  - Human
L1  - internal-pdf://2919700155/Gutterswijk-2020.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
T2  - Children and Youth Services Review Vol 113 2020, ArtID 104950
TI  - The outcome of non-residential youth care compared to residential youth care: A multilevel meta-analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-33397-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2020.104950&amp;issn=0190-7409&amp;isbn=&amp;volume=113&amp;issue=&amp;spage=104950&amp;pages=&amp;date=2020&amp;title=Children+and+Youth+Services+Review&amp;atitle=The+outcome+of+non-residential+youth+care+compared+to+residential+youth+care%3A+A+multilevel+meta-analysis.&amp;aulast=Gutterswijk&amp;pid=%3Cauthor%3EGutterswijk%2C+Raymond+V%3C%2Fauthor%3E%3CAN%3E2020-33397-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 113
ER  -
TY  - JOUR
AB  - AIM: 
To explore the efficacy of movement-based interventions to improve motor skills in preschool-age children with, or at risk of, motor impairment, including those with a diagnosis of cerebral palsy, autism spectrum disorder, and developmental coordination disorder.

METHOD: 
Relevant electronic databases were searched for randomized or quasi-randomized controlled trials. Outcomes were classified using domains of the International Classification of Functioning, Disability and Health: Children &amp; Youth version. Quality was assessed using the Physiotherapy Evidence Database scale. Risk of bias was assessed using the Cochrane Risk of Bias tool. Effect sizes were calculated using Cohen&#039;s d.

RESULTS: 
Seventeen articles exploring a heterogeneity of intervention types, population groups, and outcome measures met the inclusion criteria. Movement-based interventions did not significantly improve outcomes in either the body structure and function or activity domains in most studies. No studies used a participation outcome measure.

INTERPRETATION: 
There is a paucity of evidence exploring movement-based interventions in the preschool-age group. Although movement-based interventions showed potential for improving body structure and function and activity outcomes for children with motor impairment, results were mostly not significant. Small sample sizes, variable study quality, and risk of bias limit confidence in the results.

WHAT THIS PAPER ADDS: 
The evidence is inconclusive to support movement-based interventions in this group. No studies used outcome measures assessing participation. Variability in intervention type and study quality limit confidence in results.
AD  - Cameron, Kate L. Department of Physiotherapy, University of Melbourne, Melbourne, VIC, Australia.Cameron, Kate L. Victorian Infant Brain Studies, Murdoch Children&#039;s Research Institute, Melbourne, VIC, Australia.Albesher, Reem A. Department of Physiotherapy, University of Melbourne, Melbourne, VIC, Australia.Albesher, Reem A. Victorian Infant Brain Studies, Murdoch Children&#039;s Research Institute, Melbourne, VIC, Australia.Albesher, Reem A. Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.McGinley, Jennifer L. Department of Physiotherapy, University of Melbourne, Melbourne, VIC, Australia.Allison, Kim. Department of Physiotherapy, University of Melbourne, Melbourne, VIC, Australia.Cheong, Jeanie L Y. Victorian Infant Brain Studies, Murdoch Children&#039;s Research Institute, Melbourne, VIC, Australia.Cheong, Jeanie L Y. Neonatal Research, Royal Women&#039;s Hospital, Melbourne, VIC, Australia.Cheong, Jeanie L Y. Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, VIC, Australia.Spittle, Alicia J. Department of Physiotherapy, University of Melbourne, Melbourne, VIC, Australia.Spittle, Alicia J. Victorian Infant Brain Studies, Murdoch Children&#039;s Research Institute, Melbourne, VIC, Australia.Spittle, Alicia J. Neonatal Research, Royal Women&#039;s Hospital, Melbourne, VIC, Australia.
AN  - 31713851
AU  - Cameron,
AU  - K.
AU  - L.
AU  - Albesher,
AU  - R.
AU  - A.
AU  - McGinley,
AU  - J.
AU  - L.
AU  - Allison,
AU  - K.
AU  - Cheong,
AU  - J.
AU  - L.
AU  - Y.
AU  - Spittle,
AU  - A.
AU  - J.
DA  - Mar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/dmcn.14394
DP  - Ovid Technologies
J2  - Dev Med Child Neurol
L1  - internal-pdf://2272827552/Cameron_et_al-2020-Developmental_Medicine_&amp;_Ch.pdf
LA  - English
M3  - Review
N1  - Cameron, Kate LAlbesher, Reem AMcGinley, Jennifer LAllison, KimCheong, Jeanie L YSpittle, Alicia J
PY  - 2020
SP  - 290-296
T2  - Developmental Medicine &amp; Child Neurology
TI  - Movement-based interventions for preschool-age children with, or at risk of, motor impairment: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31713851
VL  - 62
ER  -
TY  - JOUR
AB  - OBJECTIVE: This study aimed to compare the effect of continuing and discontinuing medications on quality of life of patients with attention-deficit/hyperactivity disorder (ADHD).

DATA SOURCES: PubMed, Cochrane Library, and Embase databases were searched using generic terms for ADHD, discontinuing, continuing, pharmacotherapy, and randomized controlled trials without date or language restrictions.

STUDY SELECTION: Of the 3,672 screened studies, 9 met the predefined inclusion criteria on patients with ADHD; 5 of these 9 studies reporting on 1,463 patients (children and adolescents, n = 894; adults, n = 569) measured quality of life and were included in this meta-analysis. Only randomized, double-blind, placebo-controlled withdrawal trials of ADHD medications were included.

DATA EXTRACTION: Data were independently extracted according to the Cochrane Handbook for Systematic Reviews of Interventions. Analyses were based on random-effects models.

RESULTS: Compared with continuing medications, discontinuing them significantly worsened quality of life score in patients with ADHD (standardized mean difference [SMD] = 0.19; 95% CI, 0.08 to 0.30]). Moreover, discontinuing medications worsened this score in children and adolescents with ADHD (SMD = 0.21; 95% CI, 0.06 to 0.36) but not in adults with ADHD (SMD = 0.02; 95% CI, -0.46 to 0.50).

CONCLUSIONS: Discontinuing medications was associated with a small but statistically significant decrease in quality of life among children and adolescents with ADHD but not in adults with ADHD. Quality of life can be applied in pharmacologic interventions regarding continuing and discontinuing medication because this concept is related to individuals&#039; appraisal of their situation. Quality of life is an important factor for planning individualized ADHD medication treatment.
AD  - Tsujii, Noa. Department of Neuropsychiatry, Kindai University Faculty of Medicine, Osakasayama, Osaka, Japan.Okada, Takashi. Department of Child and Adolescent Psychiatry, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan. okada@med.nagoya-u.ac.jp.Okada, Takashi. Department of Child and Adolescent Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.Usami, Masahide. Department of Child and Adolescent Psychiatry, Kohnodai Hospital, National Center for Global Health and Medicine, Ichikawa, Chiba, Japan.Kuwabara, Hidenori. Senogawa Hospital, Hiroshima-shi, Hiroshima, Japan.Fujita, Junichi. Department of Child Psychiatry, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.Negoro, Hideki. Department of Professional Development in Education, Graduate School of Professional Development in Education, Nara University of Education, Nara-shi, Nara, Japan.Kawamura, Michiyo. Medical Sciences Group, Research Support Division, Hokkaido University Library, Sapporo, Hokkaido, Japan.Iida, Junzo. Department of Human Development, Faculty of Nursing, Nara Medical University, Kashihara, Nara, Japan.Saito, Takuya. Department of Child and Adolescent Psychiatry, Faculty of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
AN  - 32237294
AU  - Tsujii,
AU  - N.
AU  - Okada,
AU  - T.
AU  - Usami,
AU  - M.
AU  - Kuwabara,
AU  - H.
AU  - Fujita,
AU  - J.
AU  - Negoro,
AU  - H.
AU  - Kawamura,
AU  - M.
AU  - Iida,
AU  - J.
AU  - Saito,
AU  - T.
DA  - Mar 24
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.4088/JCP.19r13015
DP  - Ovid Technologies
J2  - J Clin Psychiatry
L1  - internal-pdf://0413450404/Tsujii-2020-Effect of Continuing and Discontin.pdf
LA  - English
M3  - Meta-Analysis
N1  - Using Smart Source ParsingMarTsujii, NoaOkada, TakashiUsami, MasahideKuwabara, HidenoriFujita, JunichiNegoro, HidekiKawamura, MichiyoIida, JunzoSaito, Takuya19r13015
PY  - 2020
SP  - 24
T2  - Journal of Clinical Psychiatry
TI  - Effect of Continuing and Discontinuing Medications on Quality of Life After Symptomatic Remission in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32237294
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32237294&amp;id=doi:10.4088%2FJCP.19r13015&amp;issn=0160-6689&amp;isbn=&amp;volume=81&amp;issue=3&amp;spage=&amp;pages=&amp;date=2020&amp;title=Journal+of+Clinical+Psychiatry&amp;atitle=Effect+of+Continuing+and+Discontinuing+Medications+on+Quality+of+Life+After+Symptomatic+Remission+in+Attention-Deficit%2FHyperactivity+Disorder%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Tsujii&amp;pid=%3Cauthor%3ETsujii+N%3C%2Fauthor%3E%3CAN%3E32237294%3C%2FAN%3E%3CDT%3EMeta-Analysis%3C%2FDT%3E
UR  - http://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2020/v81/19r13015.aspx&amp;Type=Article
VL  - 81
ER  -
TY  - JOUR
AB  - This meta-analysis summarized the effects of universal and targeted social and emotional learning (SEL) interventions in 48 studies on the development of social and emotional skills and the reduction of problem behaviors in 15,498 preschool students. For universal SEL interventions delivered to all students, a random-effects model with 33 primary studies showed small to medium effects for the overall development of social and emotional skills (Hedges&#039;s g = .34) and for the reduction of problem behaviors (g = .32), with an overall grand mean of g = .35. For targeted interventions, delivered to at-risk students identified as being in need of additional supports, a random-effects model with 15 primary studies showed medium effects for the overall development of social and emotional skills (Hedges&#039;s g = .44) and for the reduction of problem behaviors (g = .50), with an overall grand mean of g = .48. A meta-regression model showed that intervention program accounted for 83% of heterogeneity in the overall effect size for universal interventions. Overall, this meta-analysis demonstrated that preschool children benefit from SEL interventions in different contexts, particularly those who were identified as being in need of early intervention. Moreover, best practices for preschool SEL interventions may differ from best practices for K-12 students, given the developmental uniqueness of the preschool years. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - Murano, Dana: dana.murano@act.org; Sawyer, Jeremy E.: jeremy.ek.sawyer@gmail.com; Lipnevich, Anastasiya A.: anastasiya.lipnevich@qc.cuny.eduMurano, Dana: ACT, Inc., Center for Social, Emotional, and Academic Learning, 500 ACT Drive, Iowa City, IA, US, 52243-0168, dana.murano@act.orgMurano, Dana: ACT, Inc., Center for Social, Emotional, and Academic Learning, Iowa City, IA, USSawyer, Jeremy E.: Kingsborough Community College, City University of New York, Brooklyn, NY, USLipnevich, Anastasiya A.: Queens College, City University of New York, Flushing, NY, US
AN  - 2020-24919-003
AU  - Murano,
AU  - Dana
AU  - Sawyer,
AU  - Jeremy
AU  - E.
AU  - Lipnevich,
AU  - Anastasiya
AU  - A.
DA  - Apr
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3102/0034654320914743
DP  - Ovid Technologies
KW  - preschool, social and emotional learning, SEL, interventions, problem behavior
KW  - *Behavior Problems
KW  - *Preschool Students
KW  - *School Based Intervention
KW  - *School Learning
KW  - *Social Learning
KW  - Educational/Vocational Counseling &amp; Student Services [3580]
KW  - Human Childhood (birth-12 yrs) Preschool Age (2-5 yrs)
L1  - internal-pdf://1704278395/Murano-2020-A meta-analytic review of preschoo.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
SP  - 227-263
T2  - Review of Educational Research
TI  - A meta-analytic review of preschool social and emotional learning interventions
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2020-24919-003
UR  - https://journals.sagepub.com/doi/pdf/10.3102/0034654320914743
VL  - 90
ER  -
TY  - JOUR
AB  - <b>Purpose:</b> A systematic review was performed evaluating the effectiveness of Information and Communication Technology-based Assistive Technology (ICT-based-AT) to compensate for impaired cognition in everyday life activities. <b>Materials and methods:</b> The study was registered in PROSPERO, registration number CRD42018114913. Six databases were searched (years 2008-2019). <b>Inclusion criteria:</b> Randomized controlled trials (RCTs) or cohort studies; people with impaired cognition due to non-degenerative diseases; and evaluation of ICT-based-ATs&#039; effectiveness regarding activity and participation, including prospective memory, execution of tasks and satisfaction with task execution. Each study&#039;s level of evidence and quality were assessed using &quot;JBI Levels of Evidence&quot; and the &quot;JBI Meta-Analysis of Statistics Assessment and Review Instrument&quot;, respectively.
AN  - 32407217
AU  - Brandt,
AU  - A.
AU  - Jensen,
AU  - M.
AU  - P.
AU  - Soberg,
AU  - M.
AU  - S.
AU  - Andersen,
AU  - S.
AU  - D.
AU  - Sund,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/17483107.2020.1765032
L1  - internal-pdf://0886724166/Brandt-2020-Information and communication tech.pdf
PY  - 2020
SP  - 810-824
T2  - Disability &amp; Rehabilitation Assistive Technology
TI  - Information and communication technology-based assistive technology to compensate for impaired cognition in everyday life: a systematic review
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med18&amp;AN=32407217
UR  - https://www.tandfonline.com/doi/full/10.1080/17483107.2020.1765032
UR  - https://www.tandfonline.com/doi/pdf/10.1080/17483107.2020.1765032?needAccess=true
VL  - 15
ER  -
TY  - JOUR
AB  - **Background**: Relapse risk during the early years of first-episode psychosis (FEP) considerably increases the risk of chronicity. The effectiveness of family intervention for psychosis (FIp) for preventing relapse after FEP remains unknown. We assessed the effectiveness of FIp until 24 months of follow-up for preventing relapse and other relapse-related outcomes in patients following FEP. 

**Methods**: We searched the Cochrane, PubMed, PsycINFO, and ProQuest databases in June 2018. A systematic review with meta-analysis of randomized controlled trials (RCTs), sensitivity analyses, and publication bias were performed, comparing to treatment as usual (TAU) or TAU plus other psychosocial interventions. Outcomes assessed were relapse rates, duration of hospitalization, psychotic symptoms, and functionality. Risk ratios (RRs) and (standardized) mean differences (SMD; MD) were calculated. 

**Results**: Of the 2109 records retrieved, 14 (11 RCTs) were included. Pooled results showed that FIp was effective for preventing relapse (RR = 0.42; 95% CI = 0.29 to 0.61) compared to TAU and/or other psychosocial interventions. It also proved effective when compared to TAU alone (RR = 0.36) and TAU plus other psychosocial interventions (RR = 0.48). FIp showed benefits in reducing duration of hospitalization (TAU, MD = -3.31; other interventions, MD = -4.57) and psychotic symptoms (TAU, SMD = -0.68), and increased functionality (TAU, SMD = 1.36; other interventions, SMD = 1.41). 

**Conclusions**: These findings suggest that FIp is effective for reducing relapse rates, duration of hospitalization, and psychotic symptoms, and for increasing functionality in FEP patients up to 24 months. The study&#039;s main limitations were the inclusion of published research only; authors were not contacted for missing/additional data; and high heterogeneity regarding relapse definition was observed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Castellvi, Pere: pcobiols@ujaen.esCastellvi, Pere: Department of Psychology, University of Jaen, Campus Las Lagunillas, s/n, Jaen, Spain, 23071, pcobiols@ujaen.esCamacho-Gomez, Miguel: Department of Psychology, University of Jaen, Jaen, SpainCastellvi, Pere: Department of Psychology, University of Jaen, Jaen, Spain
AN  - 2020-73366-014
AU  - Camacho-Gomez,
AU  - M.
AU  - Castellvi,
AU  - P.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/schbul/sbz038
DP  - Ovid Technologies
KW  - family intervention, psychosis, relapse, randomized controlled trial, systematic review, meta-analysis
KW  - *Family Intervention
KW  - *Family Therapy
KW  - *Intervention
KW  - *Psychiatric Symptoms
KW  - *Psychosis
KW  - Hospitalization
KW  - Meta Analysis
KW  - Onset (Disorders)
KW  - Relapse (Disorders)
KW  - Treatment Outcomes
KW  - Schizophrenia &amp; Psychotic States [3213]
KW  - Group &amp; Family Therapy [3313]
KW  - Family Therapy
KW  - Follow-Up Studies
KW  - Humans
KW  - Outcome Assessment, Health Care
KW  - Psychotic Disorders
KW  - Randomized Controlled Trials as Topic
KW  - Secondary Prevention
KW  - Human Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older) Young Adulthood (18-29 yrs) Thirties (30-39 yrs) Middle Age (40-64 yrs)
KW  - Asia, Australia, Europe
L1  - internal-pdf://3322094384/Camacho-Gomez-2020.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2020
SP  - 98-109
T2  - Schizophrenia Bulletin
TI  - Effectiveness of family intervention for preventing relapse in first-episode psychosis until 24 months of follow-up: A systematic review with meta-analysis of randomized controlled trials
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-73366-014
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1093%2Fschbul%2Fsbz038&amp;issn=0586-7614&amp;isbn=&amp;volume=46&amp;issue=1&amp;spage=98&amp;pages=98-109&amp;date=2020&amp;title=Schizophrenia+Bulletin&amp;atitle=Effectiveness+of+family+intervention+for+preventing+relapse+in+first-episode+psychosis+until+24+months+of+follow-up%3A+A+systematic+review+with+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Camacho-Gomez&amp;pid=%3Cauthor%3ECamacho-Gomez%2C+Miguel%3C%2Fauthor%3E%3CAN%3E2020-73366-014%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942164/pdf/sbz038.pdf
VL  - 46
ER  -
TY  - JOUR
AB  - The current meta-analytic review analyzed 43 studies published in English, Chinese, and Japanese to determine the effects of caregiver involvement for promoting communication skills of individuals with ASD and IDD. Tau-U effect sizes, the Kruskal-Wallis H test, and the Dunn post hoc test were employed to calculate for moderator analyses: child age, settings, service delivery formats, and dosages of services provided to caregivers. The overall effect size for family involvement had a moderate effect on child communicative outcomes, as well as on child ages, settings, delivery formats, and dosages of services provided to caregivers of individuals with ASD and IDD. A statistically significant difference was found in children&#039;s communication outcomes between the four dosage groups of services provided to caregivers.
AN  - WOS:000583932900001
AU  - Liao,
AU  - C.
AU  - Y.
AU  - Ganz,
AU  - J.
AU  - B.
AU  - Vannest,
AU  - K.
AU  - J.
AU  - Wattanawongwan,
AU  - S.
AU  - Pierson,
AU  - L.
AU  - M.
AU  - Yllades,
AU  - V.
AU  - Li,
AU  - Y.
AU  - F.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s40489-020-00223-w
L1  - internal-pdf://1859946773/Liao.pdf
PY  - 2020
T2  - REVIEW JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
TI  - Caregiver Involvement in Communication Skills for Individuals with ASD and IDD: a Meta-analytic Review of Single-Case Research on the English, Chinese, and Japanese Literature
UR  - https://link.springer.com/content/pdf/10.1007/s40489-020-00223-w.pdf
ER  -
TY  - JOUR
AB  - **Background:** 
Effects of zinc with and without iron co-supplementation on child development are uncertain therefore the aims of this systematic review were to explore whether supplementation with zinc alone and zinc with iron in children aged 0-5 years old have beneficial or adverse effects on their mental and motor development. 

**Method(s):** 
We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, CINAHL, Web of Science and Scopus until July 2020 and included randomized controlled trials, which assessed effects of zinc supplementation with and without iron in children less than 5 years old on mental and motor development. Data were pooled by random effects model and the Standardized Mean Differences (SMDs) with 95% confidence interval were estimated. The heterogeneity was assessed by I2. 

**Result(s):** 
Twenty-five studies with 11,559 participants were eligible to be included in this systematic review. Meta-analysis was conducted with eight articles that used Bayley Scales of Infant and Toddler Development II. We concluded that zinc alone and zinc with iron co-supplementation do not have beneficial or adverse effect on child mental and motor development at 6 and 12 months of age with low to moderate quality of the evidence. Furthermore, Zinc supplementation does not have any long term effect on child development in preschool and school age children. 

**Conclusion(s):** 
Most included studies did not show the efficacy of zinc with and without iron co-supplementation on child mental and motor development up to 9 years old age. Further Randomized Controlled Trials (RCTs) need to be taken into considerations the context-based differences between countries with special focus on socio-economic differences. Copyright &copy; 2020 The Author(s).
AD  - (Sajedi, Shahshahani, Ghiasvand, Fatollahierad) Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran, Islamic Republic of (Ghiasvand) Health Economics Group, Institute of Health Research, Medical School, University of Exeter, Exeter, United Kingdom (Mosallanezhad) Department of Physiotherapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran, Islamic Republic of (Mosallanezhad) Department of Global Public Health, Karolinska Institutet, Stockholm, SwedenS. Fatollahierad, Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran, Islamic Republic of. E-mail: sh.fatollahie.rad@gmail.com
AN  - 632995549
AU  - Sajedi,
AU  - F.
AU  - Shahshahani,
AU  - S.
AU  - Ghiasvand,
AU  - H.
AU  - Mosallanezhad,
AU  - Z.
AU  - Fatollahierad,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12887-020-02340-1
DP  - Ovid Technologies
KW  - Child
KW  - Development
KW  - Iron
KW  - Zinc
KW  - article
KW  - Bayley Scales of Infant Development
KW  - child development
KW  - Cinahl
KW  - clinical trial
KW  - Cochrane Library
KW  - drug efficacy
KW  - Embase
KW  - female
KW  - human
KW  - human experiment
KW  - male
KW  - Medline
KW  - mental development
KW  - meta analysis
KW  - motor development
KW  - preschool child
KW  - randomized controlled trial (topic)
KW  - Scopus
KW  - systematic review
KW  - Web of Science
L1  - internal-pdf://0527624235/Sajedi-2020-Does zinc with and without iron co.pdf
LA  - English
PY  - 2020
T2  - BMC Pediatrics
TI  - Does zinc with and without iron co-supplementation have effect on motor and mental development of children? A systematic review and meta-analysis
UR  - http://www.biomedcentral.com/bmcpediatr/
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=632995549
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:32988376&amp;id=doi:10.1186%2Fs12887-020-02340-1&amp;issn=1471-2431&amp;isbn=&amp;volume=20&amp;issue=1&amp;spage=451&amp;pages=&amp;date=2020&amp;title=BMC+Pediatrics&amp;atitle=Does+zinc+with+and+without+iron+co-supplementation+have+effect+on+motor+and+mental+development+of+children%3F+A+systematic+review+and+meta-analysis&amp;aulast=Sajedi&amp;pid=%3Cauthor%3ESajedi+F.%3C%2Fauthor%3E%3CAN%3E632995549%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://bmcpediatr.biomedcentral.com/track/pdf/10.1186/s12887-020-02340-1
VL  - 20 (1) (no pagination)
ER  -
TY  - JOUR
AB  - **Background**
Children and adolescents are major computer and technology gadget users. While serious games hold important promises for promoting health-related behavioral change and mental health among children and adolescents, their efficacy is yet unclear. 

**Objectives**
We conducted a systematic review and meta-analysis aimed to offer a comprehensive picture on the evidence-based status of serious games for mental health promotion and health-related behavioral change in children and adolescents. 

**Method**
We included 34 clinical and experimental randomized studies investigating the efficacy of serious games on mental health promotion and health-related behavioral change in children and adolescents. 

**Results** 
Results showed a small, but significant effect size with very high heterogeneity. Participants&#039; age, number of sessions, the length of session, and study quality significantly moderated the effect size, with younger participants, fewer and shorter sessions, and lower quality of the study being associated with higher effect sizes. The effect size was not significant for follow-up measurements. 

**Conclusions** 
The evidence supporting the use of serious games in children and adolescents for purposes of health promotion is limited. These conclusions must be considered with caution given the bias of publication. We need more adequately conducted studies testing well-specified serious games before we can draw clear conclusions.
AN  - WOS:000554314500001
AU  - David,
AU  - O.
AU  - A.
AU  - Costescu,
AU  - C.
AU  - Cardos,
AU  - R.
AU  - Mogoase,
AU  - C.
DA  - Dec
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s10566-020-09566-1
L1  - internal-pdf://3998964465/David-2020.pdf
N1  - David, Oana Alexandra Costescu, Cristina Cardos, Roxana Mogoase, CristinaDavid, Oana/I-4479-2013David, Oana/0000-0001-8706-17781573-3319
PY  - 2020
SP  - 817-838
T2  - Child &amp; Youth Care Forum
TI  - How Effective are Serious Games for Promoting Mental Health and Health Behavioral Change in Children and Adolescents? A Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000554314500001
UR  - https://link.springer.com/article/10.1007%2Fs10566-020-09566-1
UR  - https://link.springer.com/content/pdf/10.1007/s10566-020-09566-1.pdf
VL  - 49
ER  -
TY  - JOUR
AB  - OBJECTIVE: Currently, pharmaceutical treatment options for autism spectrum disorder are limited. Brain glutaminergic dysregulation is observed in autism spectrum disorder. N-acetylcysteine, which can be converted to glutathione and subsequently release glutamate into the extracellular space, and thus reduce glutamatergic neurotransmission at synapses, is considered a potential drug for autism spectrum disorder treatment. Here, we analyzed the treatment effects of N-acetylcysteine on autism spectrum disorder in randomized controlled trials.

STUDY DESIGN: Updated systematic review and meta-analysis.

DATA SOURCES: By systematically searching the PubMed, Embase and Cochrane Library, we obtained five randomized controlled trials.

STUDY SELECTION: Meta-analyses were performed to examine the improvement in autistic behaviors as measured by the Aberrant Behavior Checklist, Social Responsiveness Scale and Repetitive Behavior Scale-Revised, using mean difference with a 95% confidence interval and a random-effects model.

DATA SYNTHESIS: After 8-12 weeks of N-acetylcysteine supplementation, the pooled result of four trials revealed an improvement in Aberrant Behavior Checklist total score (mean difference = 1.31, 95% confidence interval = [0.42, 2.20]). When one trial was excluded, the sensitivity test result was stronger (mean difference = 1.88, 95% confidence interval = [0.92, 2.83]). The pooled results of three trials revealed significant improvements in hyperactivity (mean difference = 4.80, 95% confidence interval = [1.20, 8.40]) and irritability (mean difference = 4.07, 95% confidence interval = [1.13, 7.04]). Regarding Social Responsiveness Scale, the pooled result of two trials showed significant improvement in social awareness after 8-12 weeks of N-acetylcysteine supplementation (mean difference = 1.34, 95% confidence interval = [0.09, 2.59]). No differences were observed in the pooled results of two trials using Repetitive Behavior Scale, either in the total or the subscales.

CONCLUSION: We concluded that N-acetylcysteine is safe and tolerable, reduces hyperactivity and irritability and enhances social awareness in children with autism spectrum disorder. However, further evidence should be sought before a general recommendation.
AD  - Lee, Tsung-Min. Substitute Military Service, Lo-Sheng Sanatorium and Hospital, Ministry of Health and Welfare, New Taipei City.Lee, Kuan-Min. Department of Family Medicine, Tri-Service General Hospital, Taipei.Lee, Chuan-Ya. Department of Psychiatry, Taipei Medical University Shuang Ho Hospital, New Taipei City.Lee, Hsin-Chien. Department of Psychiatry, Taipei Medical University Hospital, Taipei.Lee, Hsin-Chien. Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei.Tam, Ka-Wai. Center for Evidence-Based Health Care and Shared Decision Making Resource Center, Department of Medical Research, Taipei Medical University Shuang Ho Hospital, New Taipei City.Tam, Ka-Wai. Division of General Surgery, Department of Surgery, Taipei Medical University Shuang Ho Hospital, New Taipei City.Tam, Ka-Wai. Division of General Surgery, Department of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei.Tam, Ka-Wai. Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei.Tam, Ka-Wai. Cochrane Taiwan, Taipei Medical University, Taipei.Loh, El-Wui. Center for Evidence-Based Health Care and Shared Decision Making Resource Center, Department of Medical Research, Taipei Medical University Shuang Ho Hospital, New Taipei City.Loh, El-Wui. Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei.Loh, El-Wui. Cochrane Taiwan, Taipei Medical University, Taipei.Loh, El-Wui. Department of Dentistry, Taipei Medical University Shuang Ho Hospital, New Taipei City.
AN  - 32900213
AU  - Lee,
AU  - T.
AU  - M.
AU  - Lee,
AU  - K.
AU  - M.
AU  - Lee,
AU  - C.
AU  - Y.
AU  - Lee,
AU  - H.
AU  - C.
AU  - Tam,
AU  - K.
AU  - W.
AU  - Loh,
AU  - E.
AU  - W.
DA  - Sep 08
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/0004867420952540
DP  - Ovid Technologies
J2  - Aust N Z J Psychiatry
L1  - internal-pdf://0772034577/Lee-2020-Effectiveness of N-acetylcysteine in.pdf
LA  - English
N1  - Lee, Tsung-MinLee, Kuan-MinLee, Chuan-YaLee, Hsin-ChienTam, Ka-WaiLoh, El-Wui
PY  - 2020
SP  - 4867420952540
T2  - Australian &amp; New Zealand Journal of Psychiatry
TI  - Effectiveness of N-acetylcysteine in autism spectrum disorders: A meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32900213
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32900213&amp;id=doi:10.1177%2F0004867420952540&amp;issn=0004-8674&amp;isbn=&amp;volume=&amp;issue=&amp;spage=4867420952540&amp;pages=4867420952540&amp;date=2020&amp;title=Australian+%26+New+Zealand+Journal+of+Psychiatry&amp;atitle=Effectiveness+of+N-acetylcysteine+in+autism+spectrum+disorders%3A+A+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Lee&amp;pid=%3Cauthor%3ELee+TM%3C%2Fauthor%3E%3CAN%3E32900213%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0004867420952540
ER  -
TY  - JOUR
AB  - **Objective**: Narrative Exposure Therapy (NET) is a short-term trauma-focused intervention originally developed for treating survivors of war and torture. The neurobiological theoretical foundations of NET would suggest that the approach should have long term beneficial effects. We tested this assumption and also provided an extensive overview of all NET studies for adults, for children (KIDNET), and for perpetrators (Forensic Offender Rehabilitation NET; FORNET). 

**Method**: Following a systematic literature review, we conducted meta-analyses with all studies that had control conditions, and with all Randomized Controlled Trials (RCTs). We assessed between-groups short- (&lt; 6 months) and long-term (&gt;= 6 months) effect sizes for symptoms of posttraumatic stress disorder (PTSD) and depression. 

**Results**: In a total of 56 studies from 30 countries comparing 1370 participants treated with NET to 1055 controls, we found large between group effect sizes regarding the reduction of PTSD symptoms in favor of NET. Analyses of RCTs with active controls yielded small to medium effect sizes in the short-term, and large effect sizes in the long-term. 

**Conclusions**: NET, KIDNET, and FORNET yield beneficial and sustainable treatment results for severely traumatized individuals living in adverse circumstances. Studies in highly developed health care systems comparing NET with other evidence-based trauma-focused interventions are needed.
AN  - WOS:000590113300001
AU  - Siehl,
AU  - S.
AU  - Robjant,
AU  - K.
AU  - Crombach,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/10503307.2020.1847345
L1  - internal-pdf://3334156250/Siehl.pdf
PY  - 2020
T2  - PSYCHOTHERAPY RESEARCH
TI  - Systematic review and meta-analyses of the long-term efficacy of narrative exposure therapy for adults, children and perpetrators
UR  - https://www.tandfonline.com/doi/pdf/10.1080/10503307.2020.1847345?needAccess=true
ER  -
TY  - JOUR
AB  - Past research has shown student-teacher relationships (STRs) are associated with student outcomes, including improvements in academic achievement and engagement and reductions in disruptive behaviors, suspension, and risk of dropping out. Schools can support STRs universally and systematically by implementing universal, school-wide, and class-wide programs and practices that aim to facilitate high-quality STRs. 

This study applied meta-analytic and common element procedures to determine effect sizes and specific practices of universal approaches to improving STRs. 

The universal programs with the largest effects were Establish-Maintain-Restore and BRIDGE. Other programs demonstrated moderate effects in one study, with combined effect sizes revealing smaller effects. The common elements procedure identified 44 practices teachers can implement to promote positive STRs, with 14 proactive and direct practices. 

Programs with the largest effects, in general, contained the most proactive and direct practices for improving STRs. Implications of these findings and future research recommendations are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AN  - 2020-67322-004
AU  - Kincade,
AU  - L.
AU  - Cook,
AU  - C.
AU  - Goerdt,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3102/0034654320946836
L1  - internal-pdf://0812365808/Meta-analysis and common practice element-2020.pdf
PY  - 2020
SP  - 710-748
T2  - Review of Educational Research
TI  - Meta-analysis and common practice elements of universal approaches to improving student-teacher relationships
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-67322-004
UR  - https://journals.sagepub.com/doi/10.3102/0034654320946836
UR  - https://journals.sagepub.com/doi/pdf/10.3102/0034654320946836
VL  - 90
ER  -
TY  - JOUR
AB  - BACKGROUND: 
An estimated 12.8% of children and adolescents experience chronic health conditions that lead to poor quality of life, adjustment and coping issues, and concurrent mental health problems. Digital health deployment of psychosocial interventions to support youth with chronic illness has become increasingly popular with the advent of the technological advances in the digital age.

OBJECTIVE: 
Our objectives were to systematically review published efficacy studies of eHealth and mHealth (mobile health) psychosocial interventions for youths with chronic illnesses and review intervention theory and treatment components.

METHODS: 
PubMed, Embase, Web of Science, PsycInfo, and Cochrane Database of Systematic Reviews were searched for studies published from 2008 to 2019 of eHealth and mHealth psychosocial interventions designed for children and adolescents with chronic illnesses in which efficacy outcomes were reported. We excluded studies of interventions for caregivers, healthy youth, disease and medication management, and telehealth interventions that function solely as a platform to connect patients to providers via phone, text, or videoconference.

RESULTS: 
We screened 2551 articles and 133 relevant full-text articles. Sixteen efficacy studies with psychosocial and health outcomes representing 12 unique interventions met the inclusion criteria. Of the included studies, 12 were randomized controlled trials and 4 were prospective cohort studies with no comparison group. Most interventions were based in cognitive behavioral theory and designed as eHealth interventions; only 2 were designed as mHealth interventions. All but 2 interventions provided access to support staff via text, phone, email, or discussion forums. The significant heterogeneity in intervention content, intervention structure, medical diagnoses, and outcomes precluded meta-analysis. For example, measurement time points ranged from immediately postcompletion of the mHealth program to 18 months later, and we identified 39 unique outcomes of interest. The majority of included studies (11/16, 69%) reported significant changes in measured health and/or psychosocial posttreatment outcomes, with small to large effect sizes.

CONCLUSIONS: 
Although the available literature on the efficacy of eHealth and mHealth psychosocial interventions for youth with chronic illnesses is limited, preliminary research suggests some evidence of positive treatment responses. Future studies should continue to evaluate whether digital health platforms may be a viable alternative model of delivery to traditional face-to-face approaches.
AD  - Lau, Nancy. Palliative Care and Resilience Lab, Center for Clinical and Translational Research, Seattle Children&#039;s Research Institute, Seattle, WA, United States.Lau, Nancy. Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, United States.Waldbaum, Shayna. Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States.Parigoris, Ryan. Department of Psychology, University of Massachusetts Boston, Boston, MA, United States.O&#039;Daffer, Alison. Palliative Care and Resilience Lab, Center for Clinical and Translational Research, Seattle Children&#039;s Research Institute, Seattle, WA, United States.Walsh, Casey. Department of Health Services, University of Washington, Seattle, WA, United States.Walsh, Casey. Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States.Colt, Susannah F. Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.Yi-Frazier, Joyce P. Palliative Care and Resilience Lab, Center for Clinical and Translational Research, Seattle Children&#039;s Research Institute, Seattle, WA, United States.Palermo, Tonya M. Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, WA, United States.Palermo, Tonya M. Center for Child Health, Behavior, and Development, Seattle Children&#039;s Research Institute, Seattle, WA, United States.McCauley, Elizabeth. Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, United States.McCauley, Elizabeth. Center for Child Health, Behavior, and Development, Seattle Children&#039;s Research Institute, Seattle, WA, United States.Rosenberg, Abby R. Palliative Care and Resilience Lab, Center for Clinical and Translational Research, Seattle Children&#039;s Research Institute, Seattle, WA, United States.Rosenberg, Abby R. Cambia Palliative Care Center of Excellence, University of Washington, Seattle, WA, United States.Rosenberg, Abby R. Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, United States.
AN  - 33075743
AU  - Lau,
AU  - N.
AU  - Waldbaum,
AU  - S.
AU  - Parigoris,
AU  - R.
AU  - O&#039;Daffer,
AU  - A.
AU  - Walsh,
AU  - C.
AU  - Colt,
AU  - S.
AU  - F.
AU  - Yi-Frazier,
AU  - J.
AU  - P.
AU  - Palermo,
AU  - T.
AU  - M.
AU  - McCauley,
AU  - E.
AU  - Rosenberg,
AU  - A.
AU  - R.
DA  - Nov 10
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2196/22329
DP  - Ovid Technologies
J2  - JMIR Pediatr Parent
L1  - internal-pdf://0277377461/Lau-2020-eHealth and mHealth Psychosocial Inte.pdf
LA  - English
M3  - Review
N1  - Lau, NancyWaldbaum, ShaynaParigoris, RyanO&#039;Daffer, AlisonWalsh, CaseyColt, Susannah FYi-Frazier, Joyce PPalermo, Tonya MMcCauley, ElizabethRosenberg, Abby R
PY  - 2020
SP  - e22329
T2  - JMIR Pediatrics and Parenting
TI  - eHealth and mHealth Psychosocial Interventions for Youths With Chronic Illnesses: Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33075743
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33075743&amp;id=doi:10.2196%2F22329&amp;issn=2561-6722&amp;isbn=&amp;volume=3&amp;issue=2&amp;spage=e22329&amp;pages=e22329&amp;date=2020&amp;title=JMIR+Pediatrics+and+Parenting&amp;atitle=eHealth+and+mHealth+Psychosocial+Interventions+for+Youths+With+Chronic+Illnesses%3A+Systematic+Review.&amp;aulast=Lau&amp;pid=%3Cauthor%3ELau+N%3C%2Fauthor%3E%3CAN%3E33075743%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685926/pdf/pediatrics_v3i2e22329.pdf
VL  - 3
ER  -
TY  - JOUR
AB  - **Background**
Human breast milk‐fed preterm infants can accumulate nutrient deficits leading to extrauterine growth restriction. Feeding preterm infants with multi‐nutrient fortified human milk could increase nutrient accretion and growth rates and improve neurodevelopmental outcomes. Concern exists, however, that multi‐nutrient fortifiers are associated with adverse events such as feed intolerance and necrotising enterocolitis.

**Objectives**
To determine whether multi‐nutrient fortified human milk, compared with unfortified human milk, affects important outcomes (including growth rate and neurodevelopment) of preterm infants without increasing the risk of adverse effects (such as feed intolerance and necrotising enterocolitis).

**Search methods**
We searched the Cochrane Central Register of Controlled Trials (CENTRAL; 2019, Issue 9), MEDLINE via PubMed (1966 to 26 September 2019), Embase (1980 to 26 September 2019), and the Cumulative Index to Nursing and Allied Health Literature (CINAHL; 1982 to 26 September 2019). We searched clinical trials databases, conference proceedings, and reference lists of retrieved articles for randomised controlled trials and quasi‐randomised trials.

**Selection criteria**
Randomised and quasi‐randomised controlled trials that compared feeding preterm infants with multi‐nutrient (protein and energy plus minerals, vitamins, or other nutrients) fortified human breast milk versus unfortified (no added protein or energy) breast milk.

**Data collection and analysis**
We used the standard methods of Cochrane Neonatal. Two review authors separately evaluated trial quality, extracted data, and synthesised effect estimates using risk ratios (RRs), risk differences, and mean differences (MDs). We assessed the certainty of the body of evidence at the outcome level using &quot;Grading of Recommendations Assessment, Development and Evaluation&quot; (GRADE) methods.

**Main results**
We identified 18 trials in which a total of 1456 preterm infants participated. These trials were generally small and methodologically weak. Meta‐analyses provided low‐ to moderate‐certainty evidence showing that multi‐nutrient fortification of human milk increases in‐hospital rate of weight gain (MD 1.76 g/kg/d, 95% confidence interval (CI) 1.30 to 2.22), body length (MD 0.11 cm/week, 95% CI 0.08 to 0.15), or head circumference (MD 0.06 cm/week, 95% CI 0.03 to 0.08) among preterm infants. Few data on growth and developmental outcomes assessed beyond infancy are available, and these do not show effects of multi‐nutrient fortification. The data do not suggest other benefits or harms and provide low‐certainty evidence suggesting effects of multi‐nutrient fortification on the risk of necrotising enterocolitis in preterm infants (typical RR 1.37, 95% CI 0.72 to 2.63; 13 studies, 1110 infants).

**Authors&#039; conclusions**
Feeding preterm infants with multi‐nutrient fortified human breast milk compared with unfortified human breast milk is associated with modest increases in in‐hospital growth rates. Evidence is insufficient to show whether multi‐nutrient fortification has any effect on long‐term growth or neurodevelopment.
AU  - Brown,
AU  - J.
AU  - E.
AU  - V.
AU  - Lin,
AU  - L.
AU  - Embleton,
AU  - N.
AU  - D.
AU  - Harding,
AU  - J.
AU  - E.
AU  - McGuire,
AU  - W.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD000343.pub4
L1  - internal-pdf://0763299223/Brown.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Multi‐nutrient fortification of human milk for preterm infants
ER  -
TY  - JOUR
AB  - BACKGROUND: Anxiety disorders are common and impairing throughout the life course. Propensity to anxiety disorders manifests as distress and avoidance of novel stimuli (called behavioural inhibition) as early as in infancy. Already in preschool children, anxiety disorders impact emotional development and school readiness. Anxiety disorders and behavioural inhibition are prospectively associated with increased risk of mood disorders, substance use, and suicide. Therefore, early targeted prevention and treatment need to be considered. Cognitive-behavioural interventions are effective for anxiety in older age group but their efficacy for preschool children remains to be established.

METHODS: We searched PsycINFO, PubMed, and Embase until September 19th, 2019 using terms describing anxiety, behavioural inhibition, intervention, and young children. We included studies with young children participating in a cognitive-behavioural intervention for anxiety disorders, anxiety symptoms, or behavioural inhibition. We completed random-effects robust meta-analyses to (1) compare anxiety measures before and after intervention and to (2) compare intervention and control groups.

RESULTS: We identified 43 samples including 2656 participants with a mean age of 5.45 (SD = 1.00) years. Anxiety decreased after cognitive-behavioural intervention (standardized mean difference [SMD] = -1.34, 95%CI -1.59 to -1.09, p &lt; 0.0001). Anxiety decreased more in children who received intervention than in children in control conditions (SMD = -0.81, 95%CI -1.00 to -0.63, p &lt; 0.0001). The difference remained significant after correcting for potential publication bias and outliers (SMD = -0.89, 95% CI -1.13 to -0.66, p &lt; 0.0001). The improvement was maintained over follow-up.

CONCLUSIONS: Cognitive-behavioural interventions are effective for prevention and treatment of anxiety in young children.
AD  - Howes Vallis, Emily. Dalhousie University, Department of Psychiatry, Halifax, NS, Canada; Nova Scotia Health Authority, Halifax, NS, Canada.Zwicker, Alyson. Dalhousie University, Department of Psychiatry, Halifax, NS, Canada; Dalhousie University, Department of Pathology, Halifax, NS, Canada.Uher, Rudolf. Dalhousie University, Department of Psychiatry, Halifax, NS, Canada; Nova Scotia Health Authority, Halifax, NS, Canada; Institute of Psychiatry, Psychology and Neuroscience, King&#039;s College London, UK.Pavlova, Barbara. Dalhousie University, Department of Psychiatry, Halifax, NS, Canada; Nova Scotia Health Authority, Halifax, NS, Canada. Electronic address: barbara.pavlova@dal.ca.
AN  - 32891925
AU  - Howes
AU  - Vallis,
AU  - E.
AU  - Zwicker,
AU  - A.
AU  - Uher,
AU  - R.
AU  - Pavlova,
AU  - B.
DA  - Nov
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.cpr.2020.101904
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://1857703594/Howes Vallis-2020.pdf
LA  - English
M3  - Review
N1  - Howes Vallis, EmilyZwicker, AlysonUher, RudolfPavlova, BarbaraS0272-7358(20)30092-1
PY  - 2020
SP  - 101904
T2  - Clinical Psychology Review
TI  - Cognitive-behavioural interventions for prevention and treatment of anxiety in young children: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32891925
VL  - 81
ER  -
TY  - JOUR
AB  - Many interventions targeting executive function (EF) development in the preschool period, where malleability might be particularly high, have been created and evaluated. We conducted a meta-analysis of randomized controlled trials (RCTs) on the effects of these interventions on (a) EFs in preschool children from the general population as well as preschool children with (symptoms of) attention-deficit hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD), and (b) ADHD and ODD symptoms in preschool children with ADHD/ODD (symptoms). Literature search yielded 35 RCTs. Risk of bias of the individual studies was assessed. A random-effects model was used. Moderator effects were tested using mixed model analyses. The overall effects on EFs were: d = 0.46 (95% CI 0.30-0.61) for working memory (WM), d = 0.30 (95% CI 0.21-0.38) for inhibitory control (IC), d = 0.33 (95% CI - 0.04 to 0.71) for reward-related IC, and d = 0.47 (95% CI 0.28-0.66) for flexibility. In children with ADHD/ODD, mean effects were d = 0.64 (95% CI 0.31-0.96) for WM and d = 0.46 (95% CI 0.07-0.84) for IC. Studies on reward-related IC and FL were lacking. Effects on ODD and ADHD symptoms were d = 0.40 (95% CI - 0.23 to 1.03) and d = 0.28 (95% CI - 0.08 to 0.64), respectively. Interventions targeting multiple EFs and using interpersonal cognitive scaffolding approaches showed large and statistically significant effects on ADHD and ODD symptoms. In preschool children of the general population and in those with ADHD/ODD (symptoms), interventions led to an improvement of EF performance. In children with ADHD and ODD, cognitive scaffolding interventions were most effective in terms of reducing ADHD and ODD symptoms. However, more well-controlled studies need to be conducted before any firm conclusions can be drawn. Copyright &copy; 2020, The Author(s).
AD  - (Pauli-Pott, Mann, Becker) Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Hans Sachs Str. 6, Marburg 35039, Germany (Becker) Center for Mind, Brain and Behavior (CMBB), University of Marburg and Justus Liebig University Giessen, Hans-Meerwein-Strase 6, Marburg 35032, GermanyU. Pauli-Pott, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Hans Sachs Str. 6, Marburg 35039, Germany. E-mail: ursula.pauli-pott@med.uni-marburg.de
AN  - 2006073952
AU  - Pauli-Pott,
AU  - U.
AU  - Mann,
AU  - C.
AU  - Becker,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-020-01627-z
DP  - Ovid Technologies
KW  - Attention-deficit hyperactivity disorder
KW  - Executive functions
KW  - Intervention
KW  - Meta-analysis
KW  - Oppositional defiant disorder
KW  - Preschool children
KW  - article
KW  - attention deficit disorder
KW  - child
KW  - executive function
KW  - female
KW  - human
KW  - male
KW  - meta analysis
KW  - randomized controlled trial (topic)
KW  - reward
KW  - risk assessment
KW  - systematic review
KW  - working memory
L1  - internal-pdf://3588773138/Pauli-Pott-2020-Do cognitive interventions for.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - European Child and Adolescent Psychiatry.
TI  - Do cognitive interventions for preschoolers improve executive functions and reduce ADHD and externalizing symptoms? A meta-analysis of randomized controlled trials
UR  - http://www.springerlink.com/content/1018-8827
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2006073952
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:32888095&amp;id=doi:10.1007%2Fs00787-020-01627-z&amp;issn=1018-8827&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=European+Child+and+Adolescent+Psychiatry&amp;atitle=Do+cognitive+interventions+for+preschoolers+improve+executive+functions+and+reduce+ADHD+and+externalizing+symptoms%3F+A+meta-analysis+of+randomized+controlled+trials&amp;aulast=Pauli-Pott&amp;pid=%3Cauthor%3EPauli-Pott+U.%3C%2Fauthor%3E%3CAN%3E2006073952%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007/s00787-020-01627-z.pdf
ER  -
TY  - JOUR
AB  - Aggressive behaviour among adolescents has significant social and economic costs. Numerous attempts have been made to intervene to reduce aggression in adolescents. However, little is known about what factors enhance or diminish intervention effectiveness. The present systematic review and meta-analysis, therefore, seeks to quantify the effectiveness of interventions to reduce aggressive behaviour in adolescents and to identify when and for whom such interventions work best. Sixteen databases were searched for randomised controlled trials that assessed interventions to reduce aggression among adolescents. After screening 9795 records, 95 studies were included. A multi-level meta-analysis found a significant overall small-to-medium effect size (d=0.28; 95% CI [0.17, 0.39]). More effective interventions were of shorter duration, were conducted in the Middle East, were targeted at adolescents with higher levels of risk, and were facilitated by intervention professionals. Potentially active ingredients were classified using the Behaviour Change Technique Taxonomy. Behavioural practice and problem solving were components of more effective interventions targeted at the general population. Overall the findings indicate that psychosocial interventions are effective in reducing adolescent aggression. Future trials need to assess the effect of individual techniques and their combination to identify the key components that can reduce aggression in adolescents.
AD  - Castillo-Eito, Laura. Department of Psychology, The University of Sheffield, Cathedral Court, 1 Vicar Lane, Sheffield S1 2LT, United Kingdom. Electronic address: LCastilloEito1@sheffield.ac.uk.Armitage, Christopher J. Manchester Centre for Health Psychology, School of Health Sciences, University of Manchester, M13 9PL, United Kingdom; Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, M13 9PL, United Kingdom. Electronic address: chris.armitage@manchester.ac.uk.Norman, Paul. Department of Psychology, The University of Sheffield, Cathedral Court, 1 Vicar Lane, Sheffield S1 2LT, United Kingdom. Electronic address: p.norman@sheffield.ac.uk.Day, Marianne R. Department of Psychology, The University of Sheffield, Cathedral Court, 1 Vicar Lane, Sheffield S1 2LT, United Kingdom. Electronic address: pcp11mrd@sheffield.ac.uk.Dogru, Onur C. Department of Psychology, The University of Sheffield, Cathedral Court, 1 Vicar Lane, Sheffield S1 2LT, United Kingdom. Electronic address: ocdogru1@sheffield.ac.uk.Rowe, Richard. Department of Psychology, The University of Sheffield, Cathedral Court, 1 Vicar Lane, Sheffield S1 2LT, United Kingdom. Electronic address: r.rowe@sheffield.ac.uk.
AN  - 32402919
AU  - Castillo-Eito,
AU  - L.
AU  - Armitage,
AU  - C.
AU  - J.
AU  - Norman,
AU  - P.
AU  - Day,
AU  - M.
AU  - R.
AU  - Dogru,
AU  - O.
AU  - C.
AU  - Rowe,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.cpr.2020.101853
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://3701372119/Castillo-Eito-2020-How can adolescent aggressi.pdf
LA  - English
M3  - Review
N1  - Castillo-Eito, LauraArmitage, Christopher JNorman, PaulDay, Marianne RDogru, Onur CRowe, RichardS0272-7358(20)30041-6
PY  - 2020
T2  - Clinical Psychology Review
TI  - How can adolescent aggression be reduced? A multi-level meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32402919
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32402919&amp;id=doi:10.1016%2Fj.cpr.2020.101853&amp;issn=0272-7358&amp;isbn=&amp;volume=78&amp;issue=&amp;spage=101853&amp;pages=101853&amp;date=2020&amp;title=Clinical+Psychology+Review&amp;atitle=How+can+adolescent+aggression+be+reduced%3F+A+multi-level+meta-analysis.&amp;aulast=Castillo-Eito&amp;pid=%3Cauthor%3ECastillo-Eito+L%3C%2Fauthor%3E%3CAN%3E32402919%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/271858/1-s2.0-S0272735820X00043/1-s2.0-S0272735820300416/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEK%2F%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQCYoch3fid2vjt1VYQPaP6elzGCPiGV78zYUWYXgV%2BXAQIhANWgO4W5eJfjDGYhN0%2FeHbyZX6LvQladuEm6SjYwpQ%2B0KrQDCCcQAxoMMDU5MDAzNTQ2ODY1IgydQRk7X7x0VmoMHZ4qkQMU62TSERz3puAvjg0HzBQ9f3fY5rgIpUDGanvdTI%2FZy%2BhCKku9LlHGYokyyM517hnNhRpsFvKLhk4Hb659sB5aUyorqNlJZnTQtIbhTTuJ7DbTTM2P8yqXSidy3miulgFAB4xqb5XowHbW24GArycot%2BADcuWD1ApkrJqj1QRYnWnVAWTWR3r88BpdMY45PxXjj3JwkNLilzXePc4n4sebzcJuHMLrg8nfUk53qgLfWF3QvVGTLJXYEVYb8hUs%2F0vUjGyp7csYSyCwm4H7YJmpH7V5y56ndFSvHA8Gmt62SyK%2B13%2Bn5XdCf6AMwFeKfwWXreVycvl%2BLFq51QIhE7eOfZhQbskUA4lTntvW%2FieSInmJlToU4s6%2F5REol3gvJAYvYopF8pnmapmlzjt2bdoHmyxWL2HVPA2Z3yN3YXk4Jv%2FZ5Y8OaaT%2FGNriuy8MsfH17lW17J5QCfDotnA%2FMCZy9Dp90pHhWXObx1WNZ%2F4NIESDW1QlJsxRWRFkTQAoGyTPcVBzsN2TEjVKhdigRMJFYjDz8IH3BTrqAQhgypEe6AC%2BYG16tBTY3uAeKMY4hnzxJPAFiJho6KNU5r1te44Wdhwd5QrAZPKLasdG%2FTm7gwv%2BeFmXsQVIyuPVJJhCnxjrSoSF%2FYF4lUo%2FOOpJtg0vZVfd6%2B7WH0EFIqh95L49DUA4A6SgrJvELadvlAywAq0DujY%2FDglzfxhb2UqvEL%2FGgGMqPfAuZRTvHD7DGiq3vfmPNZT4CapZCm5HaQmmAo%2ByiO6a7TjxTDIkWW5eY810eUa4%2BefZQMJBBk7fKc5fbvYXTSoUM24LmqMv%2BtrOkb4kTAA216yDSIQfAUwX%2F3iEymfc5A%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200610T065332Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY5EMXBNDQ%2F20200610%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=5043454cb7a04b164cdd1f8cc64f096dbaefac223ff267c49dd93d4fa680d056&amp;hash=55f4f183fd570385ad88a27bc7ec3054ced14b28e6f1108ef5c0c9a852970603&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0272735820300416&amp;tid=spdf-b6d551c0-b19a-43fd-8ada-c050feb41064&amp;sid=b6715d5b8d7fc143477ae8442de16298848bgxrqb&amp;type=client
VL  - 78
ER  -
TY  - JOUR
AB  - **Aim** 
Interpersonal trauma exposures are associated with anxiety, depression, and substance use in youth populations (aged 12-25 years). This meta-analysis reports on the efficacy of psychological interventions on these symptom domains in addition to post-traumatic stress. 

**Methods** 
Following PRISMA guidelines, a search of electronic databases was performed for randomized controlled trials (RCTs) assessing interventions for young people following interpersonal trauma exposure. Risk of bias was assessed using the Cochrane Risk of Bias tool. Data were analysed using random-effects meta-analyses. 

**Results** 
Of the 4832 records screened, 78 studies were reviewed, and 10 RCTs, involving 679 participants (mean age 15.6 years), were analysed. There was a large pooled effect size for post-traumatic stress (7 studies, g = 1.43, 95% CI [0.37, 2.15], p = .002) and substance use (2 studies, g = 0.70, 95% CI [-0.11, 1.22], p &lt; .001) and small effect sizes for anxiety (4 studies, g = 0.30, 95% CI [0.10, 0.49], p = .003), and trend-level effect for depression (10 studies, g = 0.27, 95% CI [0.00, 0.54], p = .052). Heterogeneity was significant for post-traumatic stress and moderate for depression. 

**Conclusions** 
High-quality RCTs of psychological interventions for anxiety, depression, substance use, and post-traumatic stress symptoms in young people exposed to interpersonal trauma are scarce. While available studies show either statistically significant or trend-level efficacy for psychological interventions in reducing these symptoms, wide confidence intervals, heterogeneity and small sample size mean that results need to be interpreted with caution.
AN  - WOS:000749406900001
AU  - Peters,
AU  - W.
AU  - Rice,
AU  - S.
AU  - Alvarez-Jimenez,
AU  - M.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Halpin,
AU  - E.
AU  - Kamitsis,
AU  - I.
AU  - Santesteban-Echarri,
AU  - O.
AU  - Bendall,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/eip.13265
L1  - internal-pdf://2727283031/Relative efficacy of psychological interventio.pdf
PY  - 2020
SP  - 10
T2  - Early Intervention in Psychiatry
TI  - Relative efficacy of psychological interventions following interpersonal trauma on anxiety, depression, substance use, and PTSD symptoms in young people: A meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000749406900001
UR  - https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/eip.13265?download=true
ER  -
TY  - JOUR
AB  - BACKGROUND: Clinically significant attention-deficit/hyperactivity disorder (ADHD) symptoms are common and impairing in children and youth with autism spectrum disorder (ASD). The aim of this systematic review and meta-analysis was to (a) evaluate the efficacy and safety of pharmacotherapy for the treatment of ADHD symptoms in ASD and (b) distil findings for clinical translation.

METHODS: We searched electronic databases and clinical trial registries (1992 onwards). We selected randomized controlled trials conducted in participants &lt;25 years of age, diagnosed with ASD that evaluated ADHD outcomes (hyperactivity/impulsivity and inattention) following treatment with stimulants (methylphenidate or amphetamines), atomoxetine, alpha-2 adrenergic receptor agonists, antipsychotics, tricyclic antidepressants, bupropion, modafinil, venlafaxine, or a combination, in comparison with placebo, any of the listed medications, or behavioral therapies. Data were pooled using a random-effects model.

RESULTS: Twenty-five studies (4 methylphenidate, 4 atomoxetine, 1 guanfacine, 14 antipsychotic, 1 venlafaxine, and 1 tianeptine) were included. Methylphenidate reduced hyperactivity (parent-rated: standardized mean difference [SMD] = -.63, 95%CI = -.95,-.30; teacher-rated: SMD = -.81, 95%CI = -1.43,-.19) and inattention (parent-rated: SMD = -.36, 95%CI = -.64,-.07; teacher-rated: SMD = -.30, 95%CI = -.49,-.11). Atomoxetine reduced inattention (parent-rated: SMD = -.54, 95%CI = -.98,-.09; teacher/investigator-rated: SMD = -0.38, 95%CI = -0.75, -0.01) and parent-rated hyperactivity (parent-rated: SMD = -.49, 95%CI = -.76,-.23; teacher-rated: SMD = -.43, 95%CI = -.92, .06). Indirect evidence for significant reductions in hyperactivity with second-generation antipsychotics was also found. Quality of evidence for all interventions was low/very low. Methylphenidate was associated with a nonsignificant elevated risk of dropout due to adverse events.

CONCLUSIONS: Direct pooled evidence supports the efficacy and tolerability of methylphenidate or atomoxetine for treatment of ADHD symptoms in children and youth with ASD. The current review highlights the efficacy of standard ADHD pharmacotherapy for treatment of ADHD symptoms in children and youth with ASD. Consideration of the benefits weighed against the limitations of safety/efficacy data and lack of data evaluating long-term continuation is undertaken to help guide clinical decision-making regarding treatment of co-occurring ADHD symptoms in children and youth with ASD.
AD  - Rodrigues, Rebecca. Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.Lai, Meng-Chuan. The Margaret and Wallace McCain Centre for Child, Youth and Family Mental Health, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.Lai, Meng-Chuan. Centre for Brain and Mental Health, Department of Psychiatry, The Hospital for Sick Children, Toronto, ON, Canada.Lai, Meng-Chuan. Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.Lai, Meng-Chuan. Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK.Lai, Meng-Chuan. Department of Psychiatry, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan.Beswick, Adam. Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.Gorman, Daniel A. Centre for Brain and Mental Health, Department of Psychiatry, The Hospital for Sick Children, Toronto, ON, Canada.Gorman, Daniel A. Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.Anagnostou, Evdokia. Holland Bloorview Kids Rehabilitation Hospital, Bloorview Research Institute, Department of Pediatrics, University of Toronto, Toronto, ON, Canada.Szatmari, Peter. The Margaret and Wallace McCain Centre for Child, Youth and Family Mental Health, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.Szatmari, Peter. Centre for Brain and Mental Health, Department of Psychiatry, The Hospital for Sick Children, Toronto, ON, Canada.Szatmari, Peter. Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.Anderson, Kelly K. Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.Anderson, Kelly K. Department of Psychiatry, Schulich School of Medicine &amp; Dentistry, Western University, London, ON, Canada.Ameis, Stephanie H. The Margaret and Wallace McCain Centre for Child, Youth and Family Mental Health, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.Ameis, Stephanie H. Centre for Brain and Mental Health, Department of Psychiatry, The Hospital for Sick Children, Toronto, ON, Canada.Ameis, Stephanie H. Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
AN  - 32845025
AU  - Rodrigues,
AU  - R.
AU  - Lai,
AU  - M.
AU  - C.
AU  - Beswick,
AU  - A.
AU  - Gorman,
AU  - D.
AU  - A.
AU  - Anagnostou,
AU  - E.
AU  - Szatmari,
AU  - P.
AU  - Anderson,
AU  - K.
AU  - K.
AU  - Ameis,
AU  - S.
AU  - H.
DA  - Aug 26
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/jcpp.13305
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
L1  - internal-pdf://0253056899/Rodrigues-2020-Practitioner Review_ Pharmacolo.pdf
LA  - English
N1  - Using Smart Source ParsingAugRodrigues, RebeccaLai, Meng-ChuanBeswick, AdamGorman, Daniel AAnagnostou, EvdokiaSzatmari, PeterAnderson, Kelly KAmeis, Stephanie H
PY  - 2020
SP  - 26
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Practitioner Review: Pharmacological treatment of attention-deficit/hyperactivity disorder symptoms in children and youth with autism spectrum disorder: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32845025
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32845025&amp;id=doi:10.1111%2Fjcpp.13305&amp;issn=0021-9630&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Practitioner+Review%3A+Pharmacological+treatment+of+attention-deficit%2Fhyperactivity+disorder+symptoms+in+children+and+youth+with+autism+spectrum+disorder%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Rodrigues&amp;pid=%3Cauthor%3ERodrigues+R%3C%2Fauthor%3E%3CAN%3E32845025%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jcpp.13305?download=true
VL  - 26
ER  -
TY  - JOUR
AB  - Problems with executive functions (EF) are hallmark characteristics of Attention Deficit/Hyperactivity Disorder (ADHD). Therefore, this review analyzed the efficacy of cognitive training for EF in reducing ADHD symptomatology and improving educational, interpersonal, and occupational outcomes in children and adolescents with this disorder. 

A systematic search, using a PICO (population/participant, intervention/indicator, comparator/control, outcome) framework was carried out. From 2008 to 2018, resorting to EBSCOhost, the following databases were searched: Academic Search Complete, ERIC, MEDLINE with Full Text, PsycARTICLES, PsycINFO, and Psychology and Behavioral Sciences Collection. 

Twenty-two studies were included in this review. Of the 18 studies that reported performance-based measures of EF, 13 found improvements and five did not. Overall, 17 studies showed positive transfer effects on ADHD symptomatology, EF, academic improvement, reduced off-task behavior, and/or enhanced social skills. Of the nine studies that performed follow-up sessions, seven concluded that the treatment effects were maintained over time. 

In sum, results showed that cognitive training can be an effective intervention for children and adolescents with ADHD and might be a complementary treatment option for this disorder.
AD  - [Veloso, Andreia; Vicente, Selene G.; Filipe, Marisa G.] Univ Porto, Ctr Psychol, Fac Psychol &amp; Educ Sci, Porto, Portugal.Veloso, A (reprint author), Univ Porto, Ctr Psychol, Fac Psychol &amp; Educ Sci, Porto, Portugal.andreiaveloso@fpce.up.pt
AN  - WOS:000509984300001
AU  - Veloso,
AU  - A.
AU  - Vicente,
AU  - S.
AU  - G.
AU  - Filipe,
AU  - M.
AU  - G.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.3389/fpsyg.2019.02983
J2  - Front. Psychol.
KW  - attention deficit
KW  - hyperactivity disorder
KW  - ADHD
KW  - cognitive training
KW  - executive functions
KW  - intervention
KW  - review
KW  - deficit hyperactivity disorder
KW  - executive functions
KW  - working-memory
KW  - stimulant medication
KW  - controlled-trial
KW  - young-children
KW  - active control
KW  - adhd
KW  - programs
KW  - interventions
KW  - Psychology
L1  - internal-pdf://3030692387/Veloso-2020-Effectiveness of Cognitive Trainin.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: KG5JKTimes Cited: 0Cited Reference Count: 61Veloso, Andreia Vicente, Selene G. Filipe, Marisa G.Filipe, Marisa/0000-0001-8612-225XM2S Project through the Operational Programme for Competitiveness and Internationalization; FEDEREuropean Union (EU); [NORTE-01-0145-FEDER-028404]This research was supported by the M2S Project funded through the Operational Programme for Competitiveness and Internationalization, supported by FEDER and national funds allocated to the Portuguese Foundation for Science and Technology (NORTE-01-0145-FEDER-028404).02Frontiers media saLausanne
PY  - 2020
SP  - 17
T2  - Frontiers in Psychology
TI  - Effectiveness of Cognitive Training for School-Aged Children and Adolescents With Attention Deficit/Hyperactivity Disorder: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000509984300001
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/500233/pubmed-zip/.versions/1/.package-entries/fpsyg-10-02983/fpsyg-10-02983.pdf?sv=2015-12-11&amp;sr=b&amp;sig=uukKFZ8jpsh9ILwpUcX8MSii9zAsiQvwDOWUJOiORaA%3D&amp;se=2020-03-20T06%3A25%3A50Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyg-10-02983.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **Background:** 
Fluoxetine is a serotonin-specific reuptake inhibitor antidepressant and is the only approved pharmacological treatment for major depressive disorder (MDD) in children and adolescent. 

**Method(s):** 
We searched the published randomized controlled-trials to review fluoxetine efficacy and tolerability using the databases PubMed, EudraCT, ClinicalTrials.gov, and Cochrane Central Register of Controlled Trials for fluoxetine role in managing MDD in children and adolescents. A meta-analysis was conducted using the identified 7 clinical trials to assess efficacy using the outcomes: Children&#039;s Depression Rating Scale-Revised (CDRS-R), Clinical Global Impressions-Severity of Illness (CGI-S) and Clinical Global Impressions-Improvement (CGI-I) response rate. The risk of discontinuation due to adverse effects and common side effects were examined. 

**Result(s):** The mean difference in change from baseline for CDRS-R was -2.72 (95% confidence interval [CI], -3.96, -1.48) favoring fluoxetine treatment (P &lt;.001). Similarly, mean difference for CGI-S was -0.21 (95% CI, -0.36, -0.06). The risk ratio (RR) of discontinuing due to adverse events was 0.98 (95% CI, 0.54, 1.83), with RR for headache side effects 1.34 (95% CI, 1.03, 1.74) and rash 2.6 (95% CI, 1.32, 5.14). 

**Conclusion(s):** 
Fluoxetine demonstrates significant improvements in symptom intensity control in young patients suffering from MDD and is considered well tolerated with similar rates of trials discontinuation; however, fluoxetine was associated with a higher risk of headache and rash side effects. These findings will guide psychiatrists and pharmacists in their clinical role for supporting the care of young mental health patients. Copyright &copy; Formulary Drug Reviews 2020.
AD  - (Reyad, Plaha) University of Wolverhampton, United Kingdom (Girgis) Coventry and Warwickshire Partnership NHS Trust, United Kingdom (Mishriky) Birmingham and Solihull, Mental Health NHS Foundation Trust, United Kingdom (Mishriky) Aston University, Birmingham, United KingdomA.A. Reyad, University of Wolverhampton, United Kingdom. E-mail: a.antounreyad@wlv.ac.uk
AN  - 2005157698
AU  - Reyad,
AU  - A.
AU  - A.
AU  - Plaha,
AU  - K.
AU  - Girgis,
AU  - E.
AU  - Mishriky,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/0018578720925384
DP  - Ovid Technologies
KW  - children and adolescent
KW  - Children&#039;s Depression Rating Scale
KW  - fluoxetine
KW  - major depressive disorder
KW  - mental health
KW  - psychiatric disorders
KW  - adolescent
KW  - adverse drug reaction
KW  - article
KW  - child
KW  - clinical assessment
KW  - Clinical Global Impression scale
KW  - clinical trial
KW  - Cochrane Library
KW  - comparative effectiveness
KW  - controlled study
KW  - drug efficacy
KW  - drug withdrawal
KW  - female
KW  - headache
KW  - human
KW  - major depression
KW  - male
KW  - Medline
KW  - mental disease
KW  - meta analysis
KW  - pharmacist
KW  - psychiatrist
KW  - randomized controlled trial (topic)
KW  - rash
KW  - side effect
KW  - systematic review
L1  - internal-pdf://0215002860/Reyad-2020-Fluoxetine in the Management of Maj.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - Hospital Pharmacy.
TI  - Fluoxetine in the Management of Major Depressive Disorder in Children and Adolescents: A Meta-Analysis of Randomized Controlled Trials
UR  - http://journals.sagepub.com/loi/hpx
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2005157698
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1177%2F0018578720925384&amp;issn=0018-5787&amp;isbn=&amp;volume=&amp;issue=&amp;spage=0018578720&amp;pages=&amp;date=2020&amp;title=Hospital+Pharmacy&amp;atitle=Fluoxetine+in+the+Management+of+Major+Depressive+Disorder+in+Children+and+Adolescents%3A+A+Meta-Analysis+of+Randomized+Controlled+Trials&amp;aulast=Reyad&amp;pid=%3Cauthor%3EReyad+A.A.%3C%2Fauthor%3E%3CAN%3E2005157698%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0018578720925384
ER  -
TY  - JOUR
AB  - **Importance:** 
The number of children with prenatal opioid exposure to medication for addiction treatment (MAT) with methadone and buprenorphine for maternal opioid use disorder is increasing, but the associations of this exposure with cognitive outcomes are not well understood.

**Objective:** 
To examine the strength and consistency of findings in the medical literature regarding the association of prenatal exposure to MAT with early childhood cognitive development, particularly when accounting for variables outside MAT exposure.

**Data Sources:** 
A search strategy obtained publications from PubMed, CINAHL, PsycINFO, Web of Science, and Embase from January 1972 to June 2019. Reference lists from identified articles were searched.

**Study Selection:** 
Inclusion criteria were cohort studies, studies including children aged 1 to 60 months with at least 2 months of prenatal MAT exposure, studies using standardized direct-observation testing scales, and studies reporting means and SDs. Case reports, case series, historical controls, and reviews were excluded.

**Data Extraction and Synthesis:** 
Two authors independently selected studies for inclusion, extracted data, and assessed study quality. Data extracted included demographic characteristics, covariates, sources of bias, and effect estimates. Meta-analysis was performed using random-effects models. This study was conducted according to the Meta-analysis of Observational Studies in Epidemiology (MOOSE) guidelines and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement. Data extraction and synthesis were conducted between January 2018 and August 2019.

**Main Outcomes and Measures:** 
Cognitive test scores and demographic variability between exposed and unexposed groups.

**Results:** 
A total of 16 unique cohorts, described in 27 articles and including 1086 children (485 [44.7%] with MAT exposure), were included in a quantitative synthesis. On meta-analysis, MAT exposure was associated with lower cognitive development scores (pooled standardized mean difference, -0.57; 95% CI, -0.93 to -0.21; I2 = 81%). Multiple subanalyses on demographic characteristics (ie, maternal education, race/ethnicity, socioeconomic status, prenatal tobacco exposure, infant sex) were conducted. In the subanalysis of studies with comparable prenatal exposure to tobacco smoke, the association of MAT exposure with cognitive scores was no longer statistically significant and became homogeneous (standardized mean difference, -0.11; 95% CI, -0.42 to 0.20; I2 = 0%).

**Conclusions and Relevance:** 
In this study, predefined subanalyses demonstrated how poor recruitment, particularly imbalances in maternal tobacco use, could contribute to a negative overall association of cognitive development test scores with prenatal MAT exposure. Promoting tobacco cessation for pregnant women with opioid use disorder should be prioritized in this high-risk population.
AD  - Nelson, Leah F. Addiction Medicine Fellowship Program, Department of Family and Community Medicine, University of New Mexico, Albuquerque.Yocum, Victoria K. Honors College, University of New Mexico, Albuquerque.Patel, Keisha D. Honors College, University of New Mexico, Albuquerque.Patel, Keisha D. Combined BA/MD Program, University of New Mexico, Albuquerque.Qeadan, Fares. Division of Public Health, Department of Family and Preventive Medicine, University of Utah, Salt Lake City.Hsi, Andrew. Department of Family and Community Medicine, University of New Mexico, Albuquerque.Weitzen, Sherry. Department of Family and Community Medicine, University of New Mexico, Albuquerque.
AN  - 32186745
AU  - Nelson,
AU  - L.
AU  - F.
AU  - Yocum,
AU  - V.
AU  - K.
AU  - Patel,
AU  - K.
AU  - D.
AU  - Qeadan,
AU  - F.
AU  - Hsi,
AU  - A.
AU  - Weitzen,
AU  - S.
DA  - Mar 02
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1001/jamanetworkopen.2020.1195
DP  - Ovid Technologies
J2  - JAMA netw
L1  - internal-pdf://1374755599/Nelson-2020-Cognitive Outcomes of Young Childr.pdf
LA  - English
N1  - Nelson, Leah FYocum, Victoria KPatel, Keisha DQeadan, FaresHsi, AndrewWeitzen, Sherry
PY  - 2020
T2  - JAMA Network Open
TI  - Cognitive Outcomes of Young Children After Prenatal Exposure to Medications for Opioid Use Disorder: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32186745
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32186745&amp;id=doi:10.1001%2Fjamanetworkopen.2020.1195&amp;issn=2574-3805&amp;isbn=&amp;volume=3&amp;issue=3&amp;spage=e201195&amp;pages=e201195&amp;date=2020&amp;title=JAMA+Network+Open&amp;atitle=Cognitive+Outcomes+of+Young+Children+After+Prenatal+Exposure+to+Medications+for+Opioid+Use+Disorder%3A+A+Systematic+Review+and+Meta-analysis.&amp;aulast=Nelson&amp;pid=%3Cauthor%3ENelson+LF%3C%2Fauthor%3E%3CAN%3E32186745%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2762934/nelson_2020_oi_200066.pdf
VL  - 3
ER  -
TY  - JOUR
AB  - **Importance:** 
Interventions to discourage the use of tobacco products (including electronic nicotine delivery systems or e-cigarettes) among children and adolescents may help decrease tobacco-related illness and injury.

**Objective:** 
To update the 2013 review on primary care-relevant interventions for tobacco use prevention and cessation in children and adolescents to inform the US Preventive Services Task Force.

**Data Sources:** 
The Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic Reviews, MEDLINE, PsyINFO, and EMBASE (September 1, 2012, to June 25, 2019), with surveillance through February 7, 2020.

**Study Selection:** 
Primary care-relevant studies; randomized clinical trials and nonrandomized controlled intervention studies of children and adolescents up to age 18 years for cessation and age 25 years for prevention. Trials comparing behavioral or pharmacological interventions with no or a minimal tobacco use intervention control group (eg, usual care, attention control, wait list) were included.

**Data Extraction and Synthesis:** 
One investigator abstracted data and a second investigator checked data abstraction for accuracy. Two investigators independently assessed study quality. Studies were pooled using random-effects meta-analysis.

**Main Outcomes and Measures:** 
Tobacco use initiation; tobacco use cessation; health outcomes; harms.

**Results:** 
Twenty-four randomized clinical trials (N = 44521) met inclusion criteria. Behavioral interventions were associated with decreased likelihood of cigarette smoking initiation compared with control interventions at 7 to 36 months&#039; follow-up (13 trials, n = 21700; 7.4% vs 9.2%; relative risk [RR], 0.82 [95% CI, 0.73-0.92]). There was no statistically significant difference between behavioral interventions and controls in smoking cessation when trials were restricted to smokers (9 trials, n = 2516; 80.7% vs 84.1% continued smoking; RR, 0.97 [95% CI, 0.93-1.01]). There were no significant benefits of medication on likelihood of smoking cessation in 2 trials of bupropion at 26 weeks (n = 523; 17% [300 mg] and 6% [150 mg] vs 10% [placebo]; 24% [150 mg] vs 28% [placebo]) and 1 trial of nicotine replacement therapy at 12 months (n = 257; 8.1% vs 8.2%). One trial each (n = 2586 and n = 1645) found no beneficial intervention effect on health outcomes or on adult smoking. No trials of prevention in young adults were identified. Few trials addressed prevention or cessation of tobacco products other than cigarettes; no trials evaluated effects of interventions on e-cigarette use. There were few trials of pharmacotherapy, and they had small sample sizes.

**Conclusions and Relevance:** 
Behavioral interventions may reduce the likelihood of smoking initiation in nonsmoking children and adolescents. Research is needed to identify effective behavioral interventions for adolescents who smoke cigarettes or who use other tobacco products and to understand the effectiveness of pharmacotherapy.
AD  - Selph, Shelley. Pacific Northwest Evidence-based Practice Center, Oregon Health &amp; Science University, Portland.Patnode, Carrie. Kaiser Permanente Center for Health Research, Kaiser Permanente Research Affiliates Evidence-based Practice Center, Portland, Oregon.Bailey, Steffani R. Department of Family Medicine, Oregon Health &amp; Science University, Portland.Pappas, Miranda. Pacific Northwest Evidence-based Practice Center, Oregon Health &amp; Science University, Portland.Stoner, Ryan. Pacific Northwest Evidence-based Practice Center, Oregon Health &amp; Science University, Portland.Chou, Roger. Pacific Northwest Evidence-based Practice Center, Oregon Health &amp; Science University, Portland.
AN  - 32343335
AU  - Selph,
AU  - S.
AU  - Patnode,
AU  - C.
AU  - Bailey,
AU  - S.
AU  - R.
AU  - Pappas,
AU  - M.
AU  - Stoner,
AU  - R.
AU  - Chou,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1001/jama.2020.3332
DP  - Ovid Technologies
J2  - Jama
KW  - Adolescent
KW  - Adult
KW  - Behavior Therapy/mt [Methods]
KW  - *Behavior Therapy
KW  - Child
KW  - Counseling
KW  - Humans
KW  - *Patient Education as Topic
KW  - Practice Guidelines as Topic
KW  - *Primary Health Care
KW  - *Smoking Cessation/mt [Methods]
KW  - *Smoking Prevention/mt [Methods]
KW  - *Tobacco Use/pc [Prevention &amp; Control]
KW  - Vaping/pc [Prevention &amp; Control]
KW  - Young Adult
L1  - internal-pdf://2256960554/Selph-2020-Primary Care-Relevant Interventions.pdf
LA  - English
M3  - Meta-Analysis
Research Support, U.S. Gov&#039;t, Non-P.H.S.
Systematic Review
N1  - Selph, ShelleyPatnode, CarrieBailey, Steffani RPappas, MirandaStoner, RyanChou, Roger
PY  - 2020
SP  - 1599-1608
T2  - JAMA
TI  - Primary Care-Relevant Interventions for Tobacco and Nicotine Use Prevention and Cessation in Children and Adolescents: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=32343335
UR  - https://jamanetwork.com/journals/jama/articlepdf/2765008/jama_selph_2020_us_200007.pdf
VL  - 323
ER  -
TY  - JOUR
AB  - **Objective:** 
We conducted a meta-analysis of randomized controlled trials to explore whether vitamin D supplementation is beneficial for symptom improvement in children with autism spectrum disorder. 

**Method(s):** 
We systematically searched the PubMed database, EMBASE, Cochrane Library, Web of Science, Sino-Med, Wanfang Data, and China National Knowledge Infrastructure mainly up to September 2019. Using a fixed effects model, we calculated the standard mean difference with 95% confidence interval. Furthermore, we analyzed baseline serum 25-hydroxyvitamin D levels and outcome scores including the Social Responsiveness Scale and Child Autism Rating Scale scores after vitamin D supplementation. 

**Result(s):** 
There was no significant difference in baseline serum 25-hydroxyvitamin D levels among 203 children included from three studies in the meta-analysis. After vitamin D supplementation, the outcome scores in the experimental group were dramatically elevated compared with those in the control group (p = 0.03). 

**Conclusion(s):** 
Vitamin D supplementation improves the typical symptoms of autism spectrum disorder, as indicated by reduced Social Responsiveness Scale and Child Autism Rating Scale scores; thus, it is beneficial for children with autism spectrum disorder. Copyright &copy; 2020, Korean College of Neuropsychopharmacology
AD  - (Song, Luo, Jiang, Zhou, Wang, Chen) Department of Pediatrics, Affiliated Hospital, Southwest Medical University, Luzhou, China (Chen) Nursing Department, Affiliated Hospital of Southwest Medical University, Luzhou, China (Chen) Department of Pediatric, Sichuan Provincial Hospital for Women and Children, Chengdu, Sichuan Province, ChinaA. Chen, Department of Paediatrics, Affiliated Hospital of Southwest Medical University, Kang-Jian Area, Kangcheng Avenue, Taiping Road, Luzhou, Sichuan Province 646000, China. E-mail: zuoma78@163.com
AN  - 2006737892
AU  - Song,
AU  - L.
AU  - Luo,
AU  - X.
AU  - Jiang,
AU  - Q.
AU  - Chen,
AU  - Z.
AU  - Zhou,
AU  - L.
AU  - Wang,
AU  - D.
AU  - Chen,
AU  - A.
DA  - August
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.9758/cpn.2020.18.2.203
DP  - Ovid Technologies
KW  - Autism spectrum disorder
KW  - Children
KW  - Meta-analysis
KW  - Vitamin D
KW  - article
KW  - autism/et [Etiology]
KW  - child
KW  - human
KW  - meta analysis
KW  - outcome assessment
KW  - randomized controlled trial (topic)
KW  - systematic review
KW  - vitamin blood level
KW  - vitamin supplementation
KW  - 25 hydroxyvitamin D/ec [Endogenous Compound]
KW  - omega 3 fatty acid/cb [Drug Combination]
KW  - placebo
KW  - vitamin D/ct [Clinical Trial]
KW  - vitamin D/cb [Drug Combination]
KW  - vitamin D/cm [Drug Comparison]
KW  - vitamin D/pv [Special Situation for Pharmacovigilance]
L1  - internal-pdf://1350911424/Song-2020-Vitamin D Supplementation is Benefic.pdf
LA  - English
PY  - 2020
SP  - 203-213
T2  - Clinical Psychopharmacology and Neuroscience
TI  - Vitamin D Supplementation is Beneficial for Children with Autism Spectrum Disorder: A Meta-analysis
UR  - http://www.cpn.or.kr/journal/view.html?doi=10.9758/cpn.2020.18.2.203
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2006737892
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.9758%2Fcpn.2020.18.2.203&amp;issn=1738-1088&amp;isbn=&amp;volume=18&amp;issue=2&amp;spage=203&amp;pages=203-213&amp;date=2020&amp;title=Clinical+Psychopharmacology+and+Neuroscience&amp;atitle=Vitamin+D+Supplementation+is+Beneficial+for+Children+with+Autism+Spectrum+Disorder%3A+A+Meta-analysis&amp;aulast=Song&amp;pid=%3Cauthor%3ESong+L.%3C%2Fauthor%3E%3CAN%3E2006737892%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242097/pdf/CPN-18-203.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - **Background:** 
Pregnancy and parenthood are known to be high-risk times for mental health. However, less is known about the mental health of pregnant adolescents or adolescent parents. Despite the substantial literature on the risks associated with adolescent pregnancy, there is limited evidence on best practices for preventing poor mental health in this vulnerable group. This systematic review therefore aimed to identify whether psychosocial interventions can effectively promote positive mental health and prevent mental health conditions in pregnant and parenting adolescents. 

**Method(s):** 
We used the standardized systematic review methodology based on the process outlined in the World Health Organization&#039;s Handbook for Guidelines Development. This review focused on randomized controlled trials of preventive psychosocial interventions to promote the mental health of pregnant and parenting adolescents, as compared to treatment as usual. We searched PubMed/Medline, PsycINFO, ERIC, EMBASE and ASSIA databases, as well as reference lists of relevant articles, grey literature, and consultation with experts in the field. GRADE was used to assess the quality of evidence. 

**Result(s):** 
We included 17 eligible studies (n = 3245 participants). Interventions had small to moderate, beneficial effects on positive mental health (SMD = 0.35, very low quality evidence), and moderate beneficial effects on school attendance (SMD = 0.64, high quality evidence). There was limited evidence for the effectiveness of psychosocial interventions on mental health disorders including depression and anxiety, substance use, risky sexual and reproductive health behaviors, adherence to antenatal and postnatal care, and parenting skills. There were no available data for outcomes on self-harm and suicide; aggressive, disruptive, and oppositional behaviors; or exposure to intimate partner violence. Only two studies included adolescent fathers. No studies were based in low- or middle-income countries. 

**Conclusion(s):** 
Despite the encouraging findings in terms of effects on positive mental health and school attendance outcomes, there is a critical evidence gap related to the effectiveness of psychosocial interventions for improving mental health, preventing disorders, self-harm, and other risk behaviors among pregnant and parenting adolescents. There is an urgent need to adapt and design new psychosocial interventions that can be pilot-tested and scaled with pregnant adolescents and adolescent parents and their extended networks, particularly in low-income settings. Copyright &copy; 2020 The Author(s).
AD  - (Laurenzi, Gordon, Abrahams, Du Toit, Bradshaw, Brand, Tomlinson, Skeen) Institute for Life Course Health Research, Department of Global Health, Stellenbosch University, Tygerberg, South Africa (Melendez-Torres) Peninsula Technology Assessment Group, University of Exeter, Exeter, United Kingdom (Tomlinson) School of Nursing and Midwifery, Queens University Belfast, Belfast, United Kingdom (Ross) Department of Maternal, Newborn, Child and Adolescent Health and Ageing, World Health Organization, Geneva, Switzerland (Servili, Dua, Fleischmann) Department of Mental Health and Substance Use, World Health Organization, Geneva, Switzerland (Carvajal-Aguirre) Data and Analytics Section, Division of Data, Analysis, Planning and Monitoring, UNICEF Headquarters, New York, United States (Lai) Maternal, Newborn and Adolescent Health Unit, Health Section, UNICEF Headquarters, New York, United StatesC.A. Laurenzi, Institute for Life Course Health Research, Department of Global Health, Stellenbosch University, Tygerberg, South Africa. E-mail: christina.a.laurenzi@gmail.com
AU  - Laurenzi,
AU  - C.
AU  - A.
AU  - Gordon,
AU  - S.
AU  - Abrahams,
AU  - N.
AU  - Du
AU  - Toit,
AU  - S.
AU  - Bradshaw,
AU  - M.
AU  - Brand,
AU  - A.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Tomlinson,
AU  - M.
AU  - Ross,
AU  - D.
AU  - A.
AU  - Servili,
AU  - C.
AU  - Carvajal-Aguirre,
AU  - L.
AU  - Lai,
AU  - J.
AU  - Dua,
AU  - T.
AU  - Fleischmann,
AU  - A.
AU  - Skeen,
AU  - S.
DA  - 14 May
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12978-020-00913-y
DP  - Ovid Technologies
KW  - Adolescent parenthood
KW  - Adolescent pregnancy
KW  - Mental health
KW  - Meta-analysis
KW  - Psychosocial interventions
KW  - Systematic review
KW  - adolescent parent
KW  - adolescent sexual behavior
KW  - aggression
KW  - anxiety
KW  - automutilation
KW  - clinical effectiveness
KW  - data base
KW  - depression
KW  - disruptive behavior
KW  - evidence based medicine
KW  - female
KW  - high risk behavior
KW  - human
KW  - intermethod comparison
KW  - low income country
KW  - middle income country
KW  - oppositional defiant disorder
KW  - outcome assessment
KW  - parental behavior
KW  - partner violence
KW  - postnatal care
KW  - practice guideline
KW  - prenatal care
KW  - preventive medicine
KW  - psychosocial care
KW  - randomized controlled trial (topic)
KW  - reproductive health
KW  - review
KW  - school attendance
KW  - substance abuse
KW  - suicide
KW  - World Health Organization
L1  - internal-pdf://2054335658/Laurenzi-2020-Psychosocial interventions targe.pdf
LA  - English
M3  - Review
PY  - 2020
T2  - Reproductive Health
TI  - Psychosocial interventions targeting mental health in pregnant adolescents and adolescent parents: A systematic review
UR  - http://www.reproductive-health-journal.com/home/
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=631756188
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:32410710&amp;id=doi:10.1186%2Fs12978-020-00913-y&amp;issn=1742-4755&amp;isbn=&amp;volume=17&amp;issue=1&amp;spage=65&amp;pages=&amp;date=2020&amp;title=Reproductive+Health&amp;atitle=Psychosocial+interventions+targeting+mental+health+in+pregnant+adolescents+and+adolescent+parents%3A+A+systematic+review&amp;aulast=Laurenzi&amp;pid=%3Cauthor%3ELaurenzi+C.A.%3C%2Fauthor%3E%3CAN%3E631756188%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://reproductive-health-journal.biomedcentral.com/track/pdf/10.1186/s12978-020-00913-y
VL  - 17 (1) (no pagination)
ER  -
TY  - JOUR
AB  - **Background:** 
It is unclear whether the administration of antipsychotics to children and adolescents with autism spectrum disorders (ASD) is acceptable, equitable, and feasible. 

**Method(s):** 
We performed a systematic review to support a multidisciplinary panel in formulating a recommendation on antipsychotics, for the development of the Italian national guidelines for the management of ASD. A comprehensive search strategy was performed to find data related to intervention acceptability, health equity, and implementation feasibility. We used quantitative data from randomized controlled trials to perform a meta-analysis assessing the acceptability and tolerability of antipsychotics, and we estimated the certainty of the effect according to the GRADE approach. We extracted data from systematic reviews, primary studies, and grey literature, and we assessed the risk of bias and methodological quality of the published studies. 

**Result(s):** 
Antipsychotics were acceptable (dropouts due to any cause: RR 0.61, 95% CI 0.48-0.78, moderate certainty of evidence) and well tolerated (dropouts due to adverse events: RR 0.99, 95% CI 0.55-1.79, low certainty of evidence) by children and adolescents with ASD. Parents and clinicians did not raise significant issues concerning acceptability. We did not find studies reporting evidence of reduced equity for antipsychotics in disadvantaged subgroups of children and adolescents with ASD. Workloads, cost barriers, and inadequate monitoring of metabolic adverse events were indirect evidence of concerns for feasibility. 

**Conclusion(s):** 
Antipsychotics in children and adolescents with ASD were likely acceptable and possibly feasible. We did not find evidence of concern for equity. Copyright &copy; 2020, The Author(s).
AD  - (D&#039;Alo, De Crescenzo, Amato, Cruciani, Davoli, Minozzi, Mitrova, Saulle) Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, Rome 00154, Italy (De Crescenzo) Department of Psychiatry, University of Oxford, Oxford, United Kingdom (De Crescenzo) Pediatric University Hospital-Department (DPUO), Bambino Gesu Children&#039;s Hospital, Rome, Italy (Fulceri, Nardocci, Scattoni) Research Coordination and Support Service, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome 00161, Italy (Morgano, Schunemann) Department of Health Research Methods, Evidence and Impact (formerly Clinical Epidemiology and Biostatistics), McMaster GRADE Centre, McMaster University, Hamilton, ON, Canada (Schunemann) Department of Medicine, McMaster University, Hamilton, ON, CanadaF. De Crescenzo, Pediatric University Hospital-Department (DPUO), Bambino Gesu Children&#039;s Hospital, Rome, Italy. E-mail: franco.decrescenzo@psych.ox.ac.uk
AN  - 2007381481
AU  - D&#039;Alo,
AU  - G.
AU  - L.
AU  - De
AU  - Crescenzo,
AU  - F.
AU  - Amato,
AU  - L.
AU  - Cruciani,
AU  - F.
AU  - Davoli,
AU  - M.
AU  - Fulceri,
AU  - F.
AU  - Minozzi,
AU  - S.
AU  - Mitrova,
AU  - Z.
AU  - Morgano,
AU  - G.
AU  - P.
AU  - Nardocci,
AU  - F.
AU  - Saulle,
AU  - R.
AU  - Schunemann,
AU  - H.
AU  - J.
AU  - Scattoni,
AU  - M.
AU  - L.
AU  - Tancredi,
AU  - R.
AU  - Massagli,
AU  - A.
AU  - Valeri,
AU  - G.
AU  - Cappa,
AU  - C.
AU  - Buono,
AU  - S.
AU  - Arduino,
AU  - G.
AU  - M.
AU  - Zuddas,
AU  - A.
AU  - Reali,
AU  - L.
AU  - Molteni,
AU  - M.
AU  - Felici,
AU  - C.
AU  - Cordo,
AU  - C.
AU  - Venturini,
AU  - L.
AU  - Bellosio,
AU  - C.
AU  - Di
AU  - Tommaso,
AU  - E.
AU  - Biasci,
AU  - S.
AU  - Duff,
AU  - C.
AU  - M.
AU  - Vecchi,
AU  - S.
AU  - Basile,
AU  - M.
DA  - December
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12888-020-02956-8
DP  - Ovid Technologies
KW  - Antipsychotic agents
KW  - Autism Spectrum disorder
KW  - GRADE approach
KW  - Guideline
KW  - Systematic review
KW  - article
KW  - autism/di [Diagnosis]
KW  - autism/dt [Drug Therapy]
KW  - clinician
KW  - drug tolerability
KW  - drug use
KW  - feasibility study
KW  - health care cost
KW  - health equity
KW  - human
KW  - interdisciplinary research
KW  - meta analysis
KW  - patient care
KW  - patient monitoring
KW  - practice guideline
KW  - social acceptance
KW  - workload
KW  - aripiprazole/dt [Drug Therapy]
KW  - aripiprazole/pv [Special Situation for Pharmacovigilance]
KW  - clozapine/dt [Drug Therapy]
KW  - clozapine/pv [Special Situation for Pharmacovigilance]
KW  - haloperidol/dt [Drug Therapy]
KW  - haloperidol/pv [Special Situation for Pharmacovigilance]
KW  - lurasidone/dt [Drug Therapy]
KW  - lurasidone/pv [Special Situation for Pharmacovigilance]
KW  - olanzapine/dt [Drug Therapy]
KW  - olanzapine/pv [Special Situation for Pharmacovigilance]
KW  - risperidone/dt [Drug Therapy]
KW  - risperidone/pv [Special Situation for Pharmacovigilance]
KW  - sulpiride/dt [Drug Therapy]
KW  - sulpiride/pv [Special Situation for Pharmacovigilance]
KW  - trifluoperazine/dt [Drug Therapy]
KW  - trifluoperazine/pv [Special Situation for Pharmacovigilance]
L1  - internal-pdf://2320101445/D&#039;Alo-2020-Acceptability, equity, and feasibil.pdf
LA  - English
PY  - 2020
T2  - BMC Psychiatry
TI  - Acceptability, equity, and feasibility of using antipsychotics in children and adolescents with autism spectrum disorder: a systematic review
UR  - https://bmcpsychiatry.biomedcentral.com/
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2007381481
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33238921&amp;id=doi:10.1186%2Fs12888-020-02956-8&amp;issn=1471-244X&amp;isbn=&amp;volume=20&amp;issue=1&amp;spage=561&amp;pages=&amp;date=2020&amp;title=BMC+Psychiatry&amp;atitle=Acceptability%2C+equity%2C+and+feasibility+of+using+antipsychotics+in+children+and+adolescents+with+autism+spectrum+disorder%3A+a+systematic+review&amp;aulast=D%27Alo&amp;pid=%3Cauthor%3ED%27Alo+G.L.%3C%2Fauthor%3E%3CAN%3E2007381481%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://bmcpsychiatry.biomedcentral.com/track/pdf/10.1186/s12888-020-02956-8.pdf
VL  - 20 (1) (no pagination)
ER  -
TY  - JOUR
AB  - Children with autism spectrum disorders (ASD) experience difficulty with play, and a number of different interventions have been developed and evaluated to address this deficit. This systematic review of randomized controlled trials identified 19 studies reporting on play-based interventions for children with ASD aged 2-12 years. The components of each study, including elements of the interventions and methodological quality, were examined. A meta-analysis was completed for 11 studies, and a small but significant treatment effect was identified (Hedges&#039; g = 0.439). The current review supports future development of interventions with a focus on the child with ASD across social environments. Outcome measures and comprehensive reporting of intervention components are important considerations in future intervention development and testing. Significance for clinicians and future research is discussed. PROSPERO registration number: RD42015026263.
AD  - [Kent, Cally; Cordier, Reinie] Curtin Univ, Sch Occupat Therapy Social Work &amp; Speech Pathol, Perth, WA USA. [Cordier, Reinie; Speyer, Renee] Univ Oslo, Fac Educ Sci, Dept Special Needs Educ, Oslo, Norway. [Joosten, Annette] Australian Catholic Univ, Sch Allied Hlth, Melbourne, Vic, Australia. [Wilkes-Gillan, Sarah; Bundy, Anita] Univ Sydney, Fac Hlth Sci, Sydney, NSW, Australia. [Bundy, Anita] Colorado State Univ, Dept Occupat Therapy, Ft Collins, CO 80523 USA. [Speyer, Renee] Leiden Univ, Dept Otorhinolaryngol &amp; Head &amp; Neck Surg, Med Ctr, Leiden, Netherlands.Kent, C (reprint author), Curtin Univ, Sch Occupat Therapy Social Work &amp; Speech Pathol, Perth, WA USA.cally.smith@curtin.edu.au
AN  - WOS:000511624400006
AU  - Kent,
AU  - C.
AU  - Cordier,
AU  - R.
AU  - Joosten,
AU  - A.
AU  - Wilkes-Gillan,
AU  - S.
AU  - Bundy,
AU  - A.
AU  - Speyer,
AU  - R.
DA  - Mar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40489-019-00181-y
J2  - Rev. J. Autism Dev. Disord.
KW  - Play
KW  - Autism Spectrum disorder
KW  - Intervention
KW  - Systematic review
KW  - Meta-analysis
KW  - Child
KW  - high-functioning autism
KW  - young-children
KW  - social-skills
KW  - randomized-trial
KW  - joint attention
KW  - pretend play
KW  - school
KW  - validity
KW  - competence
KW  - toddlers
KW  - Psychology
L1  - internal-pdf://0338666896/Kent-2020.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: KI8RCTimes Cited: 2Cited Reference Count: 67Kent, Cally Cordier, Reinie Joosten, Annette Wilkes-Gillan, Sarah Bundy, Anita Speyer, ReneeJoosten, Annette/0000-0003-4722-1081; Cordier, Reinie/0000-0002-9906-5300Australian Government Research Training Program ScholarshipAustralian GovernmentDepartment of Industry, Innovation and ScienceThe authors would like to acknowledge the contribution of an Australian Government Research Training Program Scholarship in supporting this research.26Springer heidelbergHeidelberg2195-7185
PY  - 2020
SP  - 91-118
T2  - Review Journal of Autism and Developmental Disorders
TI  - A Systematic Review and Meta-analysis of Interventions to Improve Play Skills in Children with Autism Spectrum Disorder
UR  - &lt;Go to ISI&gt;://WOS:000511624400006
UR  - https://link.springer.com/article/10.1007%2Fs40489-019-00181-y
VL  - 7
ER  -
TY  - JOUR
AB  - There are several studies investigating the effects of risperidone in autism, but many of these studies are contradictory or inconclusive. This systematic review and meta-analysis investigated the effects of risperidone on five domains of Aberrant Behaviour Checklist (ABC) scale on Autism Spectrum Disorder (ASD), as well as weight gain and waist circumference. The protocol for the present systematic review and meta-analysis was registered on International Prospective Register of Systematic Reviews (PROSPERO). For this study, we analysed articles (2,459), selecting them according to the PICOS strategy (Population, Intervention, Comparison, Outcome, Study design). Although risperidone is effective for the treatment of lethargy and inadequate speech, concerns about the association between weight gain, waist circumference and risperidone require a need to evaluation of the risk-benefit ratio in its use. There was a significant association between weight gain, waist circumference and risperidone. In Conclusion, it was possible to suggest the efficacy of risperidone for the treatment of lethargy and inadequate speech. Finally, we emphasize that the risk-benefit in its use should be evaluated. Protocol number CRD42019122316.
AD  - Mano-Sousa, Brayan Jonas. Universidade Federal de Sao Joao del-Rei, Campus Centro-Oeste Dona Lindu, Divinopolis, Minas Gerais. Brazil.Pedrosa, Alessandra Moraes. Universidade Federal de Sao Joao del-Rei, Campus Centro-Oeste Dona Lindu, Divinopolis, Minas Gerais. Brazil.Alves, Bruna Cristina. Universidade Federal de Sao Joao del-Rei, Campus Centro-Oeste Dona Lindu, Divinopolis, Minas Gerais. Brazil.Galduroz, Jose Carlos Fernandes. Department of Psychobiology (Departamento de Psicobiologia), Universidade Federal de Sao Paulo, Sao Paulo, Sao Paulo. Brazil.Belo, Vinicius Silva. Universidade Federal de Sao Joao del-Rei, Campus Centro-Oeste Dona Lindu, Divinopolis, Minas Gerais. Brazil.Chaves, Valeria Ernestania. Universidade Federal de Sao Joao del-Rei, Campus Centro-Oeste Dona Lindu, Divinopolis, Minas Gerais. Brazil.Duarte-Almeida, Joaquim Mauricio. Universidade Federal de Sao Joao del-Rei, Campus Centro-Oeste Dona Lindu, Divinopolis, Minas Gerais. Brazil.
AN  - 32469700
AU  - Mano-Sousa,
AU  - B.
AU  - J.
AU  - Pedrosa,
AU  - A.
AU  - M.
AU  - Alves,
AU  - B.
AU  - C.
AU  - Galduroz,
AU  - J.
AU  - C.
AU  - F.
AU  - Belo,
AU  - V.
AU  - S.
AU  - Chaves,
AU  - V.
AU  - E.
AU  - Duarte-Almeida,
AU  - J.
AU  - M.
DA  - May 29
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.2174/1570159X18666200529151741
DP  - Ovid Technologies
J2  - Curr Neuropharmacol
L1  - internal-pdf://1678063167/Mano-Sousa-2020.pdf
LA  - English
N1  - Using Smart Source ParsingMayMano-Sousa, Brayan JonasPedrosa, Alessandra MoraesAlves, Bruna CristinaGalduroz, Jose Carlos FernandesBelo, Vinicius SilvaChaves, Valeria ErnestaniaDuarte-Almeida, Joaquim Mauricio
PY  - 2020
SP  - 29
T2  - Current Neuropharmacology
TI  - Effects of risperidone in autistic children and young adults: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32469700
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32469700&amp;id=doi:10.2174%2F1570159X18666200529151741&amp;issn=1570-159X&amp;isbn=&amp;volume=18&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Current+Neuropharmacology&amp;atitle=Effects+of+risperidone+in+autistic+children+and+young+adults%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Mano-Sousa&amp;pid=%3Cauthor%3EMano-Sousa+BJ%3C%2Fauthor%3E%3CAN%3E32469700%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.eurekaselect.com/182354/article
VL  - 29
ER  -
TY  - JOUR
AB  - **Purpose**: Persons with autism spectrum disorder (ASD) may demonstrate abnormal prosodic patterns in conversational speech, which can negatively affect social interactions. The purpose of this systematic review was to identify interventions measuring the improvement of expressive speech prosody in persons with ASD in order to support clinician&#039;s evidencebased decision making. 

**Method**: We used 13 electronic databases to search for relevant articles using terms related to autism, intervention, and speech prosody. The databases identified a total of nine articles for the title, abstract, and full-text reviews. Five more articles were included after performing descendant and reference searches. One peer-reviewed article was excluded due to insufficient data received from the authors. We coded the resulting 13 articles for report, setting, intervention, outcome, and results characteristics and methodological quality. 

**Results**: Results showed that interventions specifically targeting speech prosody using established and emerging evidence-based practices across more than 1 treatment day resulted in moderate to large improvements in speech prosody in persons with ASD. Interventions that indirectly targeted prosody or were very short resulted in small or nonsignificant effects. 

**Discussion**: The results of this literature review suggest that interventions that directly target speech prosody using established evidence-based practices for ASD may be most effective for increasing typical prosodic patterns during speech for persons with ASD. Further research is needed to establish which interventions are most effective for each age range and context.
AN  - WOS:000591205400031
AU  - Holbrook,
AU  - S.
AU  - Israelsen,
AU  - M.
DA  - NOV
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1044/2020_AJSLP-19-00127
L1  - internal-pdf://2606459396/Holbrook-2020-Speech Prosody Interventions for.pdf
PY  - 2020
SP  - 2189-2205
T2  - AMERICAN JOURNAL OF SPEECH-LANGUAGE PATHOLOGY
TI  - Speech Prosody Interventions for Persons With Autism Spectrum Disorders: A Systematic Review
VL  - 29
ER  -
TY  - JOUR
AB  - **Background:** 
Mental health conditions are leading causes of disability worldwide. Psychosocial interventions for these conditions might have a key role in their treatment, although applicability of findings to poor-resource settings might be a challenge. We aimed to evaluate the strength and credibility of evidence generated in low-income and middle-income countries (LMICs) on the efficacy of psychosocial interventions for various mental health outcomes. 

**Method(s):** 
We did an umbrella review of meta-analyses of randomised studies done in LMICs. Literature searches were done in Medline, Embase, PsychINFO, CINAHL, Cochrane Library, and Epistemonikos from Jan 1, 2010, until May 31, 2019. Systematic reviews of randomised studies investigating the efficacy of psychosocial interventions for mental health conditions in LMICs were included. Systematic reviews of promotion, prevention, and protection interventions were excluded, because the focus was on treatment interventions only. Information on first author, year of publication, outcomes, number of included studies, and reported summary meta-analytic estimates was extracted from included meta-analyses. Summary effects were recalculated using a common metric and random-effects models. We assessed between-study heterogeneity, predictive intervals, publication bias, small-study effects, and whether the results of the observed positive studies were more than expected by chance. On the basis of these calculations, strength of associations was assessed using quantitative umbrella review criteria, and credibility of evidence using the GRADE approach. This study is registered with PROSPERO, number CRD42019135711. 

**Finding(s):** 
123 primary studies from ten systematic reviews were included. The evidence on the efficacy of psychosocial interventions in adults with depression in humanitarian settings (standardised mean difference 0.87, 95% CI 0.67-1.07; highly suggestive association, GRADE: moderate) and in adults with common mental disorders (0.49, 0.36-0.62; highly suggestive association, GRADE: moderate) was supported by the most robust evidence. Highly suggestive strength of association was found for psychosocial interventions in adults with schizophrenia for functional outcomes, in adults with depression, and in adults with post-traumatic stress disorder in humanitarian settings. In children in humanitarian settings, and in children with disruptive behaviour, psychosocial interventions were supported by suggestive evidence of efficacy. 

**Interpretation(s):** 
A relatively large amount of evidence suggests the benefit of psychosocial interventions on various mental health outcomes in LMICs. However, strength of associations and credibility of evidence were quite variable, depending on the target mental health condition, type of population and setting, and outcome of interest. This varied evidence should be considered in the development of clinical, policy, and implementation programmes in LMICs and should prompt further studies to improve the strength and credibility of the evidence base. Funding(s): University of Verona. Copyright &copy; 2020 Elsevier Ltd
AD  - (Barbui, Purgato, Gastaldon, Nose, Ostuzzi, Papola, Tedeschi, Turrini) WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy (Abdulmalik, Gureje) WHO Collaborating Centre for Research and Training in Mental Health, Neurosciences and Substance Abuse, Department of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria (Acarturk) Department of Psychology, Koc University, Istanbul, Turkey (Eaton) Centre for Global Mental Health, London School of Hygiene and Tropical Medicine, London, United Kingdom (Hanlon, Jordans, Lund, Thornicroft) Centre for Global Mental Health, Institute of Psychiatry, Psychology, and Neuroscience, King&#039;s College London, London, United Kingdom (Thornicroft) Centre for Implementation Science, Institute of Psychiatry, Psychology, and Neuroscience, King&#039;s College London, London, United Kingdom (Hanlon) WHO Collaborating Centre for Mental Health Research and Capacity Building, Department of Psychiatry, School of Medicine and Centre for Innovative Drug Development and Therapeutic Trials for Africa, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia (Jordans) Amsterdam Institute for Social Science Research, University of Amsterdam, Amsterdam, Netherlands (Lund) Alan J Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa (Tol) Department of Mental Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States (Patel) Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, United StatesC. Barbui, WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Verona 37129, Italy. E-mail: corrado.barbui@univr.it
AN  - 2004677790
AU  - Barbui,
AU  - C.
AU  - Purgato,
AU  - M.
AU  - Abdulmalik,
AU  - J.
AU  - Acarturk,
AU  - C.
AU  - Eaton,
AU  - J.
AU  - Gastaldon,
AU  - C.
AU  - Gureje,
AU  - O.
AU  - Hanlon,
AU  - C.
AU  - Jordans,
AU  - M.
AU  - Lund,
AU  - C.
AU  - Nose,
AU  - M.
AU  - Ostuzzi,
AU  - G.
AU  - Papola,
AU  - D.
AU  - Tedeschi,
AU  - F.
AU  - Tol,
AU  - W.
AU  - Turrini,
AU  - G.
AU  - Patel,
AU  - V.
AU  - Thornicroft,
AU  - G.
DA  - February
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/S2215-0366%2819%2930511-5
DP  - Ovid Technologies
KW  - article
KW  - clinical effectiveness
KW  - clinical outcome
KW  - depression/th [Therapy]
KW  - disruptive behavior/th [Therapy]
KW  - human
KW  - low income country
KW  - mental disease/th [Therapy]
KW  - middle income country
KW  - posttraumatic stress disorder/th [Therapy]
KW  - priority journal
KW  - psychosocial care
KW  - randomized controlled trial (topic)
KW  - schizophrenia/th [Therapy]
KW  - systematic review
L1  - internal-pdf://1255052081/Barbui-2020.pdf
LA  - English
PY  - 2020
SP  - 162-172
T2  - The Lancet Psychiatry
TI  - Efficacy of psychosocial interventions for mental health outcomes in low-income and middle-income countries: an umbrella review
UR  - https://www.journals.elsevier.com/the-lancet-psychiatry
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2004677790
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:31948935&amp;id=doi:10.1016%2FS2215-0366%252819%252930511-5&amp;issn=2215-0366&amp;isbn=&amp;volume=7&amp;issue=2&amp;spage=162&amp;pages=162-172&amp;date=2020&amp;title=The+Lancet+Psychiatry&amp;atitle=Efficacy+of+psychosocial+interventions+for+mental+health+outcomes+in+low-income+and+middle-income+countries%3A+an+umbrella+review&amp;aulast=Barbui&amp;pid=%3Cauthor%3EBarbui+C.%3C%2Fauthor%3E%3CAN%3E2004677790%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/abs/pii/S2215036619305115?via%3Dihub
UR  - https://pdf.sciencedirectassets.com/306534/1-s2.0-S2215036620X00022/1-s2.0-S2215036619305115/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEEUaCXVzLWVhc3QtMSJGMEQCIH1L1uDCWXtyFsTbENssvTxozpOgKnGsBb8p%2BVVdTkkMAiBqreIErsi01GxtdwsGjv7Q0dIvOblYjilId15XGquq2Sq0AwguEAIaDDA1OTAwMzU0Njg2NSIMzeIflRNL2%2BvRUJWNKpEDwQTBeDIB2td6SOJIQYEFMLb%2BdG5E5gbIblTHbsQjeF6Rr7aX8qtdZdDHu4KMgLHCprc4tPZ15EtfDHj3Nghq4fzsnOBt2jnL7bOjTIdakTqv5t%2FCmtp1PHTGl9QJeYA8tuQu6G%2BsonC32X6QxzUPSkPYr%2BFxpu%2BdiAIimpkUv3bzxd5PP%2F6RlK%2FnprH5R6W%2FImlq1utw7eFq%2FqtxVlTEVbPSyFRnIDLuUqzr6r5QyRGc%2BpgUB2IKn4szoMXxjwXzGIHvI6unWYdU5%2B4y6M5gnGidBPKe51fjtY51owI8c9GwhJtt3c2AdE1Al4GkeQI42fIYdru%2BYTY7HC%2BLJA6RIxyKGTFQmN5A55lUW2mjexs4ljxiVs2cdNbEXmJ8oOLCueuebWfhGPKRcR9OTzw96KW3loCgmfCh2cKEtt9TGF%2FwiLwU%2BHB51QcvvAKxCcDiqKktxH%2FKRbUDsbVa8Rzj8eXh3mToqMFfqgWl6P%2F0RM4Yw6kb0mMKW0rvEW1DpyVvZleixStlIMZCVvsL0F5JtywwuOGo8wU67AGb0Fyf%2F2ndx3DEyA3KnhDh8jrq7s29BITK%2FRAXOYNxK1fd9POlEq0R9LXxESTwuicGM50yv5d3oy4gSlbBI%2FnLExsIW1onWpvy4SNje19IB4iFwZInQ%2BFdBR%2FYSJ%2FE4YjIsSvknxtUVklWDDiLWdpoisC0swnvYn6sfKMNESvXunjE5HJkW0y2vmUvbdoMoMzQxYCkcjak7uIksTRaQvxpc6qvMk649OuNDQjvHK2c%2BT2YW5SQXuptAYeZtvdQF4hg1a%2FiBjKrKC264EJVTw2LFKf57oFVOg5ZZ%2Fvno2Rpo5tSSy72gxIX7Cg9vQ%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200312T135024Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYRYQS3NXC%2F20200312%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=1a677709daa27bfe43632228d8b49df6d00bddb1054cbd871d31e9def24a46c2&amp;hash=46c17de691731b810cd271dc07ef735c58f35127dd4bc33eea9eb0efc94278b5&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S2215036619305115&amp;tid=spdf-12af546a-9cff-4262-9e65-ddbec54a536d&amp;sid=9c1883099b6a334ba879be48588f3f189fe9gxrqb&amp;type=client
VL  - 7
ER  -
TY  - JOUR
AB  - **Background**
Branched‐chain amino acids (BCAAs) play a vital role in neonatal nutrition. Optimal BCAA supplementation might improve neonatal nutrient storage, leading to better physical and neurological development and other outcomes.

**Objectives**
To determine the effect of BCAA supplementation on physical growth and neurological development in term and preterm neonates. We planned to make the following comparisons: parenteral nutrition with and without BCAA supplementation; enteral BCAA supplementation versus no supplementation; and any type of supplementation including enteral, parenteral and both ways versus no supplementation.To investigate the supplementation effectiveness for different dosages assessed in the eligible trials.

**Search methods**
We conducted comprehensive searches using Cochrane Neonatal&#039;s standard search strategies: Cochrane Central Register of Controlled Trials (CENTRAL 2016, Issue 6), MEDLINE, Embase and CINAHL (up to July 2016). We updated the search with CENTRAL (2019, Issue 8), MEDLINE, Embase and CINAHL (up to August 2019). We also searched clinical trials registries and reference lists of retrieved articles.

**Selection criteria**
We planned to include individual and cluster‐randomised and quasi‐randomised controlled trials comparing BCAA supplementation versus placebo or no supplementation in term and preterm neonates. We excluded trials presented only as abstracts and cross‐over trials.

**Data collection and analysis**
Two review authors independently assessed the eligibility of all potential studies identified from the search strategy. We planned to extract data using a pilot‐tested standard data extraction form and assess risk of bias of the included studies following the methods described in the Cochrane Handbook for Systematic Reviews of Interventions. We planned to analyse treatment effects and report their effect estimates as per dichotomous or continuous data with 95% confidence intervals. We planned to conduct subgroup analysis to investigate heterogeneity, and perform sensitivity analysis where possible. We planned to use fixed‐effect meta‐analysis to combine data wherever appropriate. We planned to assess evidence quality using the GRADE approach.

**Main results**
We did not identify any potentially eligible studies that met the inclusion criteria in this review.

**Authors&#039; conclusions**
We found no trial data to support or refute the idea that BCAA supplementation affects physical and neurological development and other outcomes in term and preterm neonates.
AU  - Amari,
AU  - S.
AU  - Shahrook,
AU  - S.
AU  - Namba,
AU  - F.
AU  - Ota,
AU  - E.
AU  - Mori,
AU  - R.
DA  - Oct 11
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD012273.pub2
L1  - internal-pdf://2744033370/Amari_et_al-2020-Cochrane_Database_of_Systemat.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Branched-chain amino acid supplementation for improving growth and development in term and preterm neonates
ER  -
TY  - JOUR
AB  - **Innledning** 
Barne- og ungdomsårene er preget av store følelsesmessige- og sosiale endringer. Det er særlig i disse årene at atferdsvansker, også kalt atferdsproblemer (og lignende), kan oppstå. Det fins ikke &eacute;n allment akseptert definisjon for atferdsvansker, men refererer til vedvarende opposisjonell, aggressiv og/eller destruktiv eksternaliserende atferd som er tydelig utenfor atferd som vurderes som sosialt akseptabelt. Det er vanskelig å anslå andelen barn og unge med atferdsvansker, men studier estimerer at ca. 5-10 % av barn og unge i Norge har atferdsvansker, inkludert alvorlig atferdsproblematikk som lovbrudd. Selv milde atferdsvansker kan utgjøre en stor utfordring for det enkelte barn, familier, skolekamerater, lærere og samfunnet for øvrig. Oppfølgingsstudier viser at tidlige atferdsvansker hos barn utgjør en risikofaktor for mange psykiske, fysiske og sosiale problemer blant ungdom og voksne. Det synes derfor viktig med tidlig innsats, for eksempel i hjemmet, for å forhindre videre uheldig utvikling av atferdsvansker. Målet med denne kunnskapsoppsummeringen var å få en oversikt over virkningene av ulike tiltak for barn og unge med atferdsvansker eller som har begått kriminelle handlinger. 

**Metode** 
Vi skulle besvare to spørmål: 1) Hva er effekten av tiltak for barn og unge (alder 3-18 år) som er i risiko for å utvikle alvorlige atferdsvansker? 2) Hva er effekten av sekundær- og tertiærforebyggende tiltak for barn og unge (alder 8-25 år) som har begått kriminelle handlinger? Vi besluttet å utføre en systematisk oversikt over oversikter. For å identifisere systematiske oversikter søkte en søkspesialist i åtte internasjonale litteraturdatabaser i juni 2019, inkludert OVID-basene MEDLINE, EMBASE og PsycINFO. Vi søkte også i den norske IN SUM-databasen og manuelt i referanselistene til relevante oversikter over oversikter samt i de inkluderte oversiktene. To medarbeidere utførte uavhengig av hverandre utvelgelse av relevante studier, først tittel og sammendrag og deretter fulltekster, i henhold til inklusjonskriteriene. Vi benyttet en sjekkliste for metodisk kvalitetsvurdering av systematiske oversikter og inkluderte kun de oversiktene som hadde moderat eller høy metodisk kvalitet. En forsker trakk ut data og resultater fra oversiktene og en annen forsker sjekket at data var korrekt og komplett hentet ut. Fra de inkluderte oversiktene sorterte og sammenstilte vi deretter data i tekst og laget tabeller der det var relevant. Vi vurderte til slutt den samlede dokumentasjonen for hvert av hovedutfallsmålene ved hjelp av GRADE verktøyet (Grading of Recommendations Assessment, Development, and Evaluation). Gradering går ut på å vurdere hvilken tillit vi har til resultatene som blir presentert i studiene. Vi benyttet standarddefinisjonene for å vurdere grad av tillit til resultatene: Høy kvalitet= Vi har stor tillit til at effektestimatet ligger nær den sanne effekten. Middels kvalitet= Vi har middels tillit til effektestimatet, dvs. tiltaket er trolig som estimert men kan være vesentlig ulikt. Lav kvalitet= Vi har begrenset tillit til effektestimatet, dvs. effekten er muligens som estimert men kan være vesentlig ulikt. Svært lav kvalitet= Vi har svært liten tillit til at effektestimatet ligger nær den sanne effekten, dvs. det er usikkert hvorvidt tiltaket har effekt. 

**Resultat** 
Vi inkluderte og rapporterer data fra åtte systematiske oversikter. Oversiktene var publisert mellom 2015 og 2019. Fem av oversiktene hadde moderat metodisk kvalitet mens tre hadde høy metodisk kvalitet. Oversiktene inkluderte fra 14 til 170 primærstudier hver, og vi oppsummerte totalt 319 unike primærstudier med 74 ulike tiltak gitt til om lag 50 000 studiedeltakere. Barna og ungdommene i oversiktene var mellom 1,5 og 18 år og hadde ulike atferdsvansker (hovedsakelig beskrevet som atferdsvansker, eksternaliserende problemer, atferdsforstyrrelser, atferdsproblemer). Noen hadde begått lovbrudd. Mens fire av oversiktene omhandlet tiltak for barn og unge med atferdsvansker, omhandlet de fire andre tiltak for unge som hadde begått lovbrudd. Vi fant ingen systematiske oversikter på institusjonsområdet som oppfylte inklusjonskriteriene. Kun &eacute;n av oversiktene spesifiserte hvorvidt de omhandlet sekundær- eller tertiærforebyggende tiltak, og skillet mellom de ulike nivåene av forebygging var generelt utydelig i oversiktene, men alle omhandlet tidlig intervensjon eller behandling av atferdsvansker. Effekter av tiltak for barn og unge med atferdsvansker Fire oversikter, med 241 relevante primærstudier, undersøkte effekten av 59 ulike tiltak (med ca. 30 000 deltakere) for barn og unge med atferdsvansker. Sammenlignet med kontroll viste resultatene at: &bull; foreldreveiledning fører muligens til en reduksjon i atferdsvansker hos barn (multisystemiske tiltak og ikke-multisystemiske tiltak. Multisystemisk= innsatsene rettes mot flere sosiale systemer, f.eks. foreldre og barn) &bull; effekten av psykososiale tiltak (gitt kun til barn eller kun til tenåringer) er uklar når det gjelder atferdsvansker hos barn og tenåringer &bull;psykososiale tiltak (multisystemiske eller gitt kun til foreldre) fører trolig til en reduksjon i atferdsvansker hos barn &bull;psykososiale multisystemiske tiltak fører trolig til en reduksjon i atferdsvansker hos tenåringer &bull; funksjonell familieterapi fører trolig til en reduksjon i atferdsvansker hos unge som har atferdsvansker og rusmisbruk &bull; effekten av funksjonell familieterapi er uklar når det gjelder nye lovovertredelser hos unge med atferdsvansker &bull; foreldreveiledning fører trolig til en moderat reduksjon i atferdsvansker hos barn Effekter av tiltak for barn og unge som har begått kriminelle handlinger Fire oversikter, med 80 relevante primærstudier, oppsummerte 15 ulike tiltak for å forebygge ytterligere kriminelle handlinger hos ungdom i alderen 10-18 år. Alt i alt var det ca. 21 000 ungdommer inkludert i studiene. Sammenlignet med kontroll viste resultatene at: &bull; familiebaserte tiltak fører trolig til en reduksjon i antisosial atferd, slik som arrestasjoner og lovbrudd, hos unge som har begått alvorlige lovbrudd &bull; effekten av ulike tiltak med mål om å behandle unge med ulovlig seksuell atferd er uklar når det gjelder reduksjon i antall nye lovbrudd hos unge som har begått seksuallovbrudd &bull;ulike tiltak for å bedre psykososial fungering hos unge fører muligens til en moderat bedring i psykososial fungering, slik som aggresjon, hos unge (gutter) som har begått seksuallovbrudd &bull;politibaserte avledende tiltak (police-initiated diversion) fører muligens til en liten reduksjon i antall nye lovbrudd hos unge som har begått lovbrudd 

**Diskusjon** 
Det fins mye forskning om effektene av et høyt antall tiltak av både multisystemisk og ikke-multisystemisk karakter for å begrense atferdsvansker hos barn og unge. Forskningen viser i all hovedsak at mange ulike sekundær- og tertiærforebyggende tiltak fører til en reduksjon i atferdsvansker, inkludert kriminelle handlinger, hos barn og unge. For de fleste av utfallsmålene i denne kunnskapsoppsummeringen er vi sikker på retningen på effekten, nemlig at mange av disse tiltakene gir en reduksjon i atferdsvansker hos barn og unge. Vi er mindre sikre på størrelsen på effekten. Det fins best dokumentasjon for at tiltak som er familiebaserte, og da særlig innbefattet foreldreveiledning, reduserer atferdsvansker hos både barn og unge. Resultatene viser tydelig at både multisystemiske og ikke-multisystemiske psykososiale tiltak &ndash; f.eks. veiledning i atferdshåndtering, Parent-Child Interaction Therapy, multisystemisk terapi, De utrolige årene, Trippel P &ndash; trolig gir en vedvarende reduksjon i atferdsvansker hos barn og unge. I familier der barn og unge har atferdsvansker støtter disse resultatene dermed bruk av foreldreveiledning, f.eks. når det gjelder atferdshåndtering. Det kan være at slike tiltak er effektive fordi de bedrer samspillet mellom foreldre og barn. Praksisfeltet bør videre være oppmerksom på at effekten er større for foreldreveiledning som er indikativ (rettet mot høyrisikogrupper) enn selektiv (rettet mot risikogrupper). Med hensyn til spesifikke teknikker som bør være en del av foreldreveiledning viser dokumentasjonen at spesifikk ros, generell positiv tilbakemelding samt logiske konsekvenser som en disiplinerende praksis fører til større effekter enn andre teknikker. Gitt resultatene, det brede spektrum av deltakere, geografiske steder og miljøer mener vi det er det sannsynlig at resultatene er overførbare til mange forskjellige kontekster, inkludert Norge. 

**Konklusjon** 
Det fins ingen vidunderkur som alltid vil redusere og fjerne atferdsvansker hos barn og unge, men denne oppsummeringen viser at det fins et knippe tiltak som synes å begrense atferdsvansker. For praksisfeltet og beslutningstakere er det viktig å merke seg den vedvarende positive effekten av familiebaserte tiltak, og da særlig innbefattet foreldreveiledning, slik at de gjennom å gjøre endringer i egen oppdragerpraksis kan veilede barna til endringer i atferd.
AU  - Berg,
AU  - R.
AU  - Johansen,
AU  - T.
AU  - B.
AU  - Jacobsen
AU  - Jardim,
AU  - P.
AU  - S.
AU  - Forsetlund,
AU  - L.
AU  - Nguyen,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/tiltak-for-barn-og-unge-med-atferdsvansker-eller-som-har-begatt-kriminelle-handlinger-rapport-2020.pdf
PY  - 2020
T2  - Folkehelseinstituttet
TI  - Tiltak for barn og unge med atferdsvansker eller som har begått kriminelle handlinger: en oversikt over systematiske oversikter
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Social anxiety disorder (SoAD) in youth is often treated with a generic form of cognitive behavioural therapy (CBT). Some studies have suggested that primary SoAD is associated with lower recovery rates following generic CBT compared with other anxiety disorders.AIMS: This systematic review and meta-analysis investigated recovery rates following generic CBT for youth with primary SoAD versus other primary anxiety disorders.

METHOD: 
Five databases (PsycINFO, Web of Science, PubMed, Embase, Medline) were searched for randomised controlled trials of generic CBT for child and/or adolescent anxiety.

RESULTS: 
Ten trials met criteria for inclusion in the systematic review, six of which presented sufficient data for inclusion in the meta-analysis. Sixty-seven did not report data on recovery rates relative to primary diagnosis. While most individual studies included in the systematic review were not sufficiently powered to detect a difference in recovery rates between diagnoses, there was a pattern of lower recovery rates for youth with primary SoAD. Across the trials included in the meta-analysis, the post-CBT recovery rate from primary SoAD (35%) was significantly lower than the recovery rate from other primary anxiety disorders (54%).

CONCLUSIONS: 
Recovery from primary SoAD is significantly less likely than recovery from any other primary anxiety disorder following generic CBT in youth. This suggests a need for research to enhance the efficacy of CBT for youth SoAD.
AD  - Evans, Rachel. Department of Psychology, IoPPN, King&#039;s College London, London, UK.Clark, David M. Department of Experimental Psychology, University of Oxford, Oxford, UK.Leigh, Eleanor. Department of Experimental Psychology, University of Oxford, Oxford, UK.
AN  - 33298222
AU  - Evans,
AU  - R.
AU  - Clark,
AU  - D.
AU  - M.
AU  - Leigh,
AU  - E.
DA  - Dec 10
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1017/S135246582000079X
DP  - Ovid Technologies
J2  - Behav
L1  - internal-pdf://2034171783/Evans-2020-Are young people with primary socia.pdf
LA  - English
N1  - Evans, RachelClark, David MLeigh, Eleanor
PY  - 2020
SP  - 1-18
T2  - Behavioural &amp; Cognitive Psychotherapy
TI  - Are young people with primary social anxiety disorder less likely to recover following generic CBT compared to young people with other primary anxiety disorders? A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33298222
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33298222&amp;id=doi:10.1017%2FS135246582000079X&amp;issn=1352-4658&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-18&amp;date=2020&amp;title=Behavioural+%26+Cognitive+Psychotherapy&amp;atitle=Are+young+people+with+primary+social+anxiety+disorder+less+likely+to+recover+following+generic+CBT+compared+to+young+people+with+other+primary+anxiety+disorders%3F+A+systematic+review+and+meta-analysis.&amp;aulast=Evans&amp;pid=%3Cauthor%3EEvans+R%3C%2Fauthor%3E%3CAN%3E33298222%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/B6B096B83EE37C6EAAE0DE32CB4B09CA/S135246582000079Xa.pdf/div-class-title-are-young-people-with-primary-social-anxiety-disorder-less-likely-to-recover-following-generic-cbt-compared-to-young-people-with-other-primary-anxiety-disorders-a-systematic-review-and-meta-analysis-div.pdf
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Infants in the neonatal intensive care unit (NICU) are exposed to many stressors. There is growing evidence that chronic stress early in life has long-term neurodevelopmental implications. Skin-to-skin care (SSC) is an intervention used to reduce stress in the NICU.

CLINICAL QUESTION: 
In premature infants in the NICU, what is the available evidence that SSC improves short-term physiologic stress outcomes compared with incubator care?

SEARCH STRATEGY: 
PubMed and CINAHL were searched for terms related to SSC, stress, physiology, and premature infants. Of 1280 unique articles, 19 were identified that reported on research studies comparing SSC with incubator care in the NICU and reported stress-related physiologic outcome measures.

RESULTS: 
Although there have been some mixed findings, the research supports that SSC improves short-term cardiorespiratory stress outcomes compared with incubator care. The evidence is clearer for studies reporting stress hormone outcomes, with strong evidence that SSC reduces cortisol and increases oxytocin levels in preterm infants.

IMPLICATIONS FOR PRACTICE AND RESEARCH: 
SSC is safe and has stress-reducing benefits. SSC should be considered an essential component to providing optimal care in the NICU. More research is needed to determine the timing of initiation, duration, and frequency of SSC to optimize the stress-reducing benefits. Future research should include the most fragile infants, who are most likely to benefit from SSC, utilize power analyses to ensure adequate sample sizes, and use sophisticated data collection and analysis techniques to more accurately evaluate the effect of SSC on infants in the NICU.
AD  - Pados, Britt Frisk. Boston College William F. Connell School of Nursing (Dr Pados) and Boston College Carolyn A. and Peter S. Lynch School of Education (Mr Hess), Chestnut Hill, Massachusetts.
AN  - 30893092
AU  - Pados,
AU  - B.
AU  - F.
AU  - Hess,
AU  - F.
DA  - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1097/ANC.0000000000000596
DP  - Ovid Technologies
J2  - Adv Neonat Care
L1  - internal-pdf://2987043349/pados.pdf
LA  - English
N1  - Pados, Britt FriskHess, Francis
PY  - 2020
SP  - 48-58
T2  - Advances in Neonatal Care
TI  - Systematic Review of the Effects of Skin-to-Skin Care on Short-Term Physiologic Stress Outcomes in Preterm Infants in the Neonatal Intensive Care Unit
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30893092
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30893092&amp;id=doi:10.1097%2FANC.0000000000000596&amp;issn=1536-0903&amp;isbn=&amp;volume=20&amp;issue=1&amp;spage=48&amp;pages=48-58&amp;date=2020&amp;title=Advances+in+Neonatal+Care&amp;atitle=Systematic+Review+of+the+Effects+of+Skin-to-Skin+Care+on+Short-Term+Physiologic+Stress+Outcomes+in+Preterm+Infants+in+the+Neonatal+Intensive+Care+Unit.&amp;aulast=Pados&amp;pid=%3Cauthor%3EPados+BF%3C%2Fauthor%3E%3CAN%3E30893092%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 20
ER  -
TY  - JOUR
AB  - **Background:** 
Recommended first line treatment for children and adolescent eating disorders is outpatient therapy. However, a significant number of children and adolescents with eating disorders continue to require inpatient treatment during the course of their illness. The effect of psychological treatments in an inpatient setting on outcomes at the time of discharge remains unclear. This paper presents the results of a review of the literature on outcomes at the time of discharge following inpatient psychological treatment for children and adolescents with eating disorders.

**Main body:** 
The majority of studies found were observational and of low quality. The most consistently reported positive outcome of inpatient treatment is weight gain. Results related to symptom change and motivation vary between studies. Within the inpatient setting, there is considerable heterogeneity in the types of treatments offered, goals of treatment, length of stay and outcomes measured.

**Conclusion:** 
There remains a paucity of high-quality studies examining the effect of psychological treatments provided to children and adolescents in an inpatient setting. The significant heterogeneity between studies makes it not possible to compare across studies. Future research should aim to resolve these deficiencies in order to better determine the specific factors that contribute to positive outcomes of inpatient treatment for children and adolescents with eating disorders.
AD  - Isserlin, Leanna. Department of Psychiatry, Children&#039;s Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON K1H 8L1 Canada.Isserlin, Leanna. Children&#039;s Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1 Canada.Spettigue, Wendy. Department of Psychiatry, Children&#039;s Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON K1H 8L1 Canada.Spettigue, Wendy. Children&#039;s Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1 Canada.Norris, Mark. Children&#039;s Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 8L1 Canada.Norris, Mark. Division of Adolescent Health, Department of Pediatrics, Children&#039;s Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON K1H 8L1 Canada.Couturier, Jennifer. Department of Psychiatry &amp; Behavioural Neurosciences, McMaster University, Hamilton, ON L8N3Z5 Canada.
AN  - 32637099
AU  - Isserlin,
AU  - L.
AU  - Spettigue,
AU  - W.
AU  - Norris,
AU  - M.
AU  - Couturier,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s40337-020-00307-2
DP  - Ovid Technologies
J2  - J Eat Disord
L1  - internal-pdf://1302888904/Isserlin-2020-Outcomes of inpatient psychologi.pdf
LA  - English
M3  - Review
N1  - Isserlin, LeannaSpettigue, WendyNorris, MarkCouturier, Jennifer
PY  - 2020
SP  - 32
T2  - Journal of Eating Disorders
TI  - Outcomes of inpatient psychological treatments for children and adolescents with eating disorders at time of discharge: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32637099
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32637099&amp;id=doi:10.1186%2Fs40337-020-00307-2&amp;issn=2050-2974&amp;isbn=&amp;volume=8&amp;issue=&amp;spage=32&amp;pages=32&amp;date=2020&amp;title=Journal+of+Eating+Disorders&amp;atitle=Outcomes+of+inpatient+psychological+treatments+for+children+and+adolescents+with+eating+disorders+at+time+of+discharge%3A+a+systematic+review.&amp;aulast=Isserlin&amp;pid=%3Cauthor%3EIsserlin+L%3C%2Fauthor%3E%3CAN%3E32637099%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333407/pdf/40337_2020_Article_307.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Various parent training interventions have been shown to have some effect on the symptoms of children with autism. We carried out a systematic review and meta-analyses to assess effectiveness of parental training for children with autism on their symptoms and parental stress.

METHODS: 
Four electronic databases, CINAHL, EMBASE, MEDLINE and PsycINFO were searched until March 2020 for relevant literature. Two reviewers independently screened bibliographies using an eligibility checklist and extracted data using a structured proforma. We have also carried out meta-analyses when data were available for pooling.

RESULTS: 
Seventeen papers from 15 studies were included for data analysis. Fifteen papers showed a positive treatment effect when compared with the control group, although not always significant. Meta-analysis based on pooled data from only two studies in each respective intervention, showed small to moderate treatment effects for three interventions, DIR/Floortime, Pivotal Response and Parent focused training respectively.

CONCLUSIONS: 
As in previous systematic reviews there was a mild to moderate treatment effects of three specific types of interventions respectively. However, it was difficult to draw any definitive conclusion about the effectiveness and generalisability of any intervention because of the wide variation in the interventions, control groups, outcome measures, small sample size, small number of studies in meta-analysis, overlap between the intervention and control procedures used in the included studies. There is an urgent need for experts in various international centres to jointly standardise a parent training intervention for children with autism and carry out a large scale RCT to assess its clinical and economic effectiveness.
AD  - Deb, Shoumitro Shoumi. Imperial College London Faculty of Medicine, London, UK. s.deb@imperial.ac.uk.Retzer, Ameeta. Centre for Patient Reported Outcomes Research, Institute of Applied Health Research, University of Birmingham, Birmingham, UK.Roy, Meera. Worcestershire Health and Care NHS Trust, Worcester, UK.Acharya, Rupali. Imperial College London Faculty of Medicine, London, UK.Limbu, Bharati. Imperial College London Faculty of Medicine, London, UK.Roy, Ashok. Coventry and Warwickshire Partnership NHS Trust, Coventry, UK.
AN  - 33287762
AU  - Deb,
AU  - S.
AU  - S.
AU  - Retzer,
AU  - A.
AU  - Roy,
AU  - M.
AU  - Acharya,
AU  - R.
AU  - Limbu,
AU  - B.
AU  - Roy,
AU  - A.
DA  - Dec 07
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12888-020-02973-7
DP  - Ovid Technologies
J2  - BMC Psychiatry
L1  - internal-pdf://2573071030/Deb-2020-The effectiveness of parent training.pdf
LA  - English
N1  - Deb, Shoumitro ShoumiRetzer, AmeetaRoy, MeeraAcharya, RupaliLimbu, BharatiRoy, Ashok
PY  - 2020
SP  - 583
T2  - BMC Psychiatry
TI  - The effectiveness of parent training for children with autism spectrum disorder: a systematic review and meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=33287762
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33287762&amp;id=doi:10.1186%2Fs12888-020-02973-7&amp;issn=1471-244X&amp;isbn=&amp;volume=20&amp;issue=1&amp;spage=583&amp;pages=583&amp;date=2020&amp;title=BMC+Psychiatry&amp;atitle=The+effectiveness+of+parent+training+for+children+with+autism+spectrum+disorder%3A+a+systematic+review+and+meta-analyses.&amp;aulast=Deb&amp;pid=%3Cauthor%3EDeb+SS%3C%2Fauthor%3E%3CAN%3E33287762%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7720449/pdf/12888_2020_Article_2973.pdf
VL  - 20
ER  -
TY  - JOUR
AB  - Multicomponent positive psychology interventions are increasing in the general population but the study of its effectiveness in adolescents is still scarce, especially in the school context. Previous meta-analyses have reported that multicomponent positive psychology interventions increase well-being and reduce distress outcomes. However, the results on these outcomes limit their samples to adult populations. The aim of the current systematic review and meta-analysis is to evaluate and compare the immediate but also long-lasting effects of school-based multicomponent positive psychology interventions aimed at increasing well-being indicators of mental health (i.e., subjective and psychological well-being) and reducing the most common psychological distress indicators (i.e., depression, anxiety, and stress) in adolescents. A total of 9 randomized and non-randomized controlled trials from the searched literature met inclusion criteria for the meta-analysis. The results showed small effects for subjective well-being (g = 0.24), psychological well-being (g = 0.25), and depression symptoms (g = 0.28). Removing low-quality studies led to a slight decrease in the effect sizes for subjective well-being and a considerable increase for psychological well-being and depression symptoms. The relevant moderation analyses had an effect on subjective well-being and depression symptoms. The present systematic review and meta-analysis found evidence for the efficacy of school-based multicomponent positive psychology interventions in improving mental health in the short and long-term. Small effects for subjective well-being, psychological well-being, and depression symptoms were identified. Effects for psychological well-being and depression symptoms remained significant over time. In light of our results, education policy-makers and practitioners are encouraged to include positive practices within the schools&#039; curriculum as effective and easily implemented tools that help to enhance adolescents&#039; mental health. Further research is needed in order to strengthen the findings about school-based multicomponent positive psychology interventions in adolescents.
AD  - Tejada-Gallardo, Claudia. Universitat de Lleida Avinguda de l&#039;estudi general, ndegree 4, 25001, Lleida, Spain. claudia.tejada@udl.cat.Blasco-Belled, Ana. Universitat de Lleida Avinguda de l&#039;estudi general, ndegree 4, 25001, Lleida, Spain.Torrelles-Nadal, Cristina. Universitat de Lleida Avinguda de l&#039;estudi general, ndegree 4, 25001, Lleida, Spain.Alsinet, Carles. Universitat de Lleida Avinguda de l&#039;estudi general, ndegree 4, 25001, Lleida, Spain.
AN  - 32683592
AU  - Tejada-Gallardo,
AU  - C.
AU  - Blasco-Belled,
AU  - A.
AU  - Torrelles-Nadal,
AU  - C.
AU  - Alsinet,
AU  - C.
DA  - Jul 18
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10964-020-01289-9
DP  - Ovid Technologies
J2  - J Youth Adolesc
L1  - internal-pdf://0005080137/Tejada-Gallardo-2020.pdf
LA  - English
N1  - Using Smart Source ParsingJulTejada-Gallardo, ClaudiaBlasco-Belled, AnaTorrelles-Nadal, CristinaAlsinet, Carles
PY  - 2020
SP  - 18
T2  - Journal of Youth &amp; Adolescence
TI  - Effects of School-based Multicomponent Positive Psychology Interventions on Well-being and Distress in Adolescents: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32683592
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32683592&amp;id=doi:10.1007%2Fs10964-020-01289-9&amp;issn=0047-2891&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Journal+of+Youth+%26+Adolescence&amp;atitle=Effects+of+School-based+Multicomponent+Positive+Psychology+Interventions+on+Well-being+and+Distress+in+Adolescents%3A+A+Systematic+Review+and+Meta-analysis.&amp;aulast=Tejada-Gallardo&amp;pid=%3Cauthor%3ETejada-Gallardo+C%3C%2Fauthor%3E%3CAN%3E32683592%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10964-020-01289-9
UR  - https://link.springer.com/content/pdf/10.1007/s10964-020-01289-9.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - Sexual assault and rape are common forms of sexual violence/abuse. The psychological/health consequences represent significant and ongoing harm. It seems imperative that victim/survivors receive evidence-based support within first response settings. To assess what psychosocial interventions work for victim/survivors of a recent sexual assault. Twenty-seven electronic databases were systematically searched. Narrative data synthesis was used to read across studies. Reporting format follows PRISMA checklist. Ten studies were identifed including range of interventions. The evidence is sparse and scientifically weak, common flaws are reviewed. There is some weak evidence for the impact of video and cognitive behavioural therapy (CBT) based interventions, especially trauma processing. There is a gap in the evidence base on psychosocial interventions for victim/survivors of sexual assault and higher quality research is required.
AD  - Lomax, Jane. University of Bath, Bath, UK.Meyrick, Jane. University of the West of England Bristol, Bristol, UK.
AN  - 32838568
AU  - Lomax,
AU  - J.
AU  - Meyrick,
AU  - J.
DA  - Aug 24
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1359105320950799
DP  - Ovid Technologies
J2  - J Health Psychol
L1  - internal-pdf://1966953527/Lomax-2020-Systematic Review_ Effectiveness of.pdf
LA  - English
N1  - Lomax, JaneMeyrick, Jane
PY  - 2020
SP  - 1359105320950799
T2  - Journal of Health Psychology
TI  - Systematic Review: Effectiveness of psychosocial interventions on wellbeing outcomes for adolescent or adult victim/survivors of recent rape or sexual assault
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32838568
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32838568&amp;id=doi:10.1177%2F1359105320950799&amp;issn=1359-1053&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1359105320950799&amp;pages=1359105320950799&amp;date=2020&amp;title=Journal+of+Health+Psychology&amp;atitle=Systematic+Review%3A+Effectiveness+of+psychosocial+interventions+on+wellbeing+outcomes+for+adolescent+or+adult+victim%2Fsurvivors+of+recent+rape+or+sexual+assault.&amp;aulast=Lomax&amp;pid=%3Cauthor%3ELomax+J%3C%2Fauthor%3E%3CAN%3E32838568%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1359105320950799
ER  -
TY  - JOUR
AB  - **Background:** 
Obsessive&ndash;compulsive disorder (OCD) is a common psychiatric illness in children and adolescents. Previous evidence suggests that fluoxetine is effective in the treatment of OCD in children and adolescents. However, those studies had small sample sizes. As a result, a systematic review, which is a more powerful method to calculate the true effect size, can be applied to examine the efficacy, acceptability and tolerability of fluoxetine in the treatment of OCD in children and adolescents. 

**Objectives:** 
The aims of this study were to review the efficacy, acceptability and tolerability of fluoxetine in the treatment of OCD in children and adolescents. 

**Study appraisal and synthesis methods:** 
The titles and abstracts collected from electronic databases were evaluated. Then, the full-text versions of relevant studies were thoroughly assessed and extracted.

**Results:** 
A total of 188 randomized patients in three RCTs of fluoxetine versus placebo and one RCT of fluoxetine versus citalopram were included in this review. Considering efficacious outcomes, the pooled mean change score of the CY-BOCS in the fluoxetine-treated group was significantly greater than that in the placebo-treated group. Additionally, the CGI-S in the fluoxetine-treated group and the pooled mean change score of the NIMH-OC were also significantly different from those in the placebo-treated group. 

**Limitation:** 
This review included studies with small sample sizes. 

**Conclusions and implications of key findings:** 
Fluoxetine is associated with a significantly greater reduction in OCD severity, as measured by the CY-BOCS, NIMH-OC and CGI-S, in children and adolescents. Additionally, it is well tolerated in children and adolescents. The acceptability is comparable to that of the placebo-treated group. Nonetheless, further large prospective trials should be conducted to confirm these outcomes.
AD  - Maneeton, Narong. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.Maneeton, Benchalak. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.Karawekpanyawong, Nuntaporn. Psychiatric Nursing Division, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand.Woottiluk, Pakapan. Psychiatric Nursing Division, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand.Putthisri, Suwannee. Department of Psychiatry, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.Srisurapanon, Manit. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
AN  - 32242450
AU  - Maneeton,
AU  - N.
AU  - Maneeton,
AU  - B.
AU  - Karawekpanyawong,
AU  - N.
AU  - Woottiluk,
AU  - P.
AU  - Putthisri,
AU  - S.
AU  - Srisurapanon,
AU  - M.
DA  - Apr 03
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/08039488.2020.1744037
DP  - Ovid Technologies
J2  - Nord J Psychiatry
L1  - internal-pdf://1841938111/Maneeton-2020.pdf
LA  - English
N1  - Maneeton, NarongManeeton, BenchalakKarawekpanyawong, NuntapornWoottiluk, PakapanPutthisri, SuwanneeSrisurapanon, Manit
PY  - 2020
SP  - 1-9
T2  - Nordic Journal of Psychiatry
TI  - Fluoxetine in acute treatment of children and adolescents with obsessive-compulsive disorder: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32242450
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32242450&amp;id=doi:10.1080%2F08039488.2020.1744037&amp;issn=0803-9488&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-9&amp;date=2020&amp;title=Nordic+Journal+of+Psychiatry&amp;atitle=Fluoxetine+in+acute+treatment+of+children+and+adolescents+with+obsessive-compulsive+disorder%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Maneeton&amp;pid=%3Cauthor%3EManeeton+N%3C%2Fauthor%3E%3CAN%3E32242450%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/full/10.1080/08039488.2020.1744037
UR  - https://www.tandfonline.com/doi/pdf/10.1080/08039488.2020.1744037?needAccess=true
ER  -
TY  - JOUR
AB  - AIM: 
The aim of this narrative review was to evaluate the evidence for interventions for children&#039;s secure attachment relationships and parents&#039; caregiving sensitivity that could potentially be implemented in the context of a well-baby clinic.

METHODS: 
Literature search on programmes for parental caregiving sensitivity and secure attachment for infants 0-24 months. Randomised controlled trials (RCTs) published 1995-2018 with interventions starting from one week postpartum, and with a maximum of 12 sessions (plus potential booster session) were included.

RESULTS: 
We identified 25 studies, of which 22 studied effects of home-based programmes using video feedback techniques. Positive effects of these interventions in families at risk were found on parental caregiving sensitivity and to a lesser extent also on children&#039;s secure or disorganised attachment. The effects of two of these programmes were supported by several RCTs. Three intervention studies based on group and individual psychotherapy showed no significant positive effects. Most of the interventions targeted mothers only.

CONCLUSIONS: 
The review found some evidence for positive effects of selective interventions with video-feedback techniques for children&#039;s secure attachment and strong evidence for positive effects on parental caregiving sensitivity. Important knowledge gaps were identified for universal interventions and interventions for fathers and parents with a non-Western background.
AD  - Bergstrom, Malin. Sachs&#039; Children and Youth hospital, Stockholm, Sweden.Bergstrom, Malin. Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden.Bergstrom, Malin. CHESS, Centre for Health Equity Studies, Stockholm University and Karolinska Institutet, Stockholm, Sweden.Gebreslassie, Mihretab. Department of Public Health and Caring Sciences, Uppsala University.Hedqvist, Maria. Department of Public Health and Caring Sciences, Uppsala University.Lindberg, Lene. Department of Public Health Sciences, Karolinska Institutet.Sarkadi, Anna. Department of Public Health and Caring Sciences, Uppsala University.Hjern, Anders. Sachs&#039; Children and Youth hospital, Stockholm, Sweden.Hjern, Anders. Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden.Hjern, Anders. CHESS, Centre for Health Equity Studies, Stockholm University and Karolinska Institutet, Stockholm, Sweden.
AN  - 32027407
AU  - Bergstrom,
AU  - M.
AU  - Gebreslassie,
AU  - M.
AU  - Hedqvist,
AU  - M.
AU  - Lindberg,
AU  - L.
AU  - Sarkadi,
AU  - A.
AU  - Hjern,
AU  - A.
DA  - Feb 06
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/apa.15212
DP  - Ovid Technologies
J2  - Acta Paediatr
L1  - internal-pdf://3964966275/Bergstrom-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingFebBergstrom, MalinGebreslassie, MihretabHedqvist, MariaLindberg, LeneSarkadi, AnnaHjern, Anders
PY  - 2020
SP  - 06
T2  - Acta Paediatrica
TI  - Narrative review of interventions suitable for Well-baby Clinics to promote infant attachment security and parents&#039; sensitivity
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32027407
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32027407&amp;id=doi:10.1111%2Fapa.15212&amp;issn=0803-5253&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Acta+Paediatrica&amp;atitle=Narrative+review+of+interventions+suitable+for+Well-baby+Clinics+to+promote+infant+attachment+security+and+parents%27+sensitivity.&amp;aulast=Bergstrom&amp;pid=%3Cauthor%3EBergstrom+M%3C%2Fauthor%3E%3CAN%3E32027407%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/apa.15212
VL  - 06
ER  -
TY  - JOUR
AB  - Of the substantial literature on interventions to improve the poor health of children in out of home care, little focuses on lifestyle factors such as physical activity. This review identifies if physical activity interventions are effective for this population, and if so which type of activity and for what health outcomes. A systematic review of 14 social science and physical activity databases was conducted in November 2019. Included articles examined the effect of a physical activity intervention on any health or wellbeing outcome, for children or adolescents under 20 years of age whose primary condition for admission to care was abuse, neglect or parental incapacity. A final 12 studies were identified, dated from 1989 to 2019, covering nine countries and with a mix of designs; eight Randomised Control Trials (RCT&#039;s), three single group trials and one qualitative study. Most interventions showed benefit, with the best evidence for rhythmic movement on visual motor integration and behaviour, yoga in relation to balance, flexibility and muscle strength, and initiative or general recreation activities for self-concept, self-efficacy and general psychological temperament. However, for some studies the effect may be moderated by other co-occurring interventions, like group social activities. Further research is required before these results could be confidently generalised across different settings, with particular gaps in relation to children and young people residing in foster or kinship care and for studies examining the effect of sports participation. The results of this review indicate that physical activity could be an effective intervention to address health concerns for children in out of home care and should therefore be considered in policies and program design. It is important to note that specific types of activity could not yet confidently be recommended over others.
AN  - WOS:000517661700064
AU  - Wilson,
AU  - B.
AU  - Barnett,
AU  - L.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.childyouth.2020.104765
L1  - internal-pdf://2811798997/Wilson-2020.pdf
N1  - Wilson, Brendan Barnett, Lisa M.1873-7765
PY  - 2020
T2  - Children and Youth Services Review
TI  - Physical activity interventions to improve the health of children and adolescents in out of home care - A systematic review of the literature
UR  - &lt;Go to ISI&gt;://WOS:000517661700064
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0190740919309132?via%3Dihub
VL  - 110
ER  -
TY  - JOUR
AB  - **2.1 Background**
Anxiety is a common problem in school‐aged children with ASD. CBT and other psychosocial interventions have been developed as alternatives to pharmacological intervention to treat anxiety symptoms in students with ASD without co‐occurring intellectual disability. This present synthesis of evidence is a systematic review and meta‐analysis examining the efficacy of interventions for reducing anxiety among school‐aged children with ASD.

**2.2 Objectives**
This review aims to address the question of what the relative effectiveness of interventions is for managing anxiety of school‐aged children with ASD in school, family, and clinical settings.

**2.3 Search methods**
The following databases were searched for references from 1996 up to 31 December 2018: EBSCO (including Academic Search Complete, British Education Index, CINHAHL, Education Research Complete, ERIC, PsychINFO, and SocINDEX), Informit (A&thinsp;+&thinsp;Education), Elsevier (including EMBASE and SCOPUS), PubMed and Proquest (CBCA Complete). We also searched the reference lists of published and unpublished literature papers, as well as gray literature sources, selected websites, trial registries, and experts in the field of autism to inquire about studies.

**2.4 Selection criteria**
Studies were included in the review if they met the following criteria.
1. The patient/client population was school‐aged children (5 to 18 years old) diagnosed with ASD (inclusive of autism, ASD, Autistic Disorder, Asperger&#039;s Disorder, Asperger Syndrome, atypical autism, and PDD‐NOS) by a professional eligible to diagnose these conditions, and also experiencing anxiety symptoms or a diagnosis of an anxiety disorder provided by a professional eligible to diagnose such conditions.
2. The intervention was focused on reducing anxiety symptoms and included at least one of the following seven elements: (a) psychoeducation, (b) exposure, (c) cognitive restructuring, (d) parent training or parent psychoeducation, (e) relaxation, (f) modeling, and (g) self‐monitoring.
3. At least one outcome measure was a standardized continuous measure of anxiety (parent, clinician or self‐reported).
4. The study was published between the years 1996 and 2018.

**2.5 Data collection and analysis**
Four authors independently selected and appraised studies for inclusion, while two authors evaluated the risk of bias in each subsequently included study. All outcome data were continuous, from which standardized mean difference effect sizes were calculated. We conducted random effects meta‐analysis, which means we assumed individual studies would provide different estimates of treatment effects. Where outlier studies were identified, analyses were repeated after the outlier had been removed from the list of studies. Analyses were conducted separately according to the respondent on the outcome measure of anxiety: clinician, parent or subject (child or youth). Moderator analyses were undertaken to examine differences in effect sizes depending on whether or not the family was involved and whether treatment occurred in groups or individually.

**2.6 Results**
Eighteen randomized controlled trials (RCTs) and six quasi‐experimental studies met the inclusion criteria. These studies evaluated the effects of interventions targeting anxiety in 931 (764 male and 167 females) participants aged 3&ndash;19 years. Overall, the effects of interventions on anxiety were statistically significant and of moderate to high effectiveness, compared to waitlist and treatment‐as‐usual control conditions at posttreatment (standardized mean difference after removal of outliers SMD &thinsp;=&thinsp;&minus;0.71, 95% confidence interval [CI]: &minus;0.97, &minus;0.46; z &thinsp;=&thinsp;&minus;5.42, p &thinsp;&lt;&thinsp;.01), where SMDs of 0.05, 0.19, 0.45, and 0.70 were taken to be indicative of low, moderate, high, and very high effects, respectively. Results also suggested the reported effectiveness of treatment varied as a function of the informant on outcome measures&mdash;clinician reports indicate a very high statistically significant effect (SMD &thinsp;=&thinsp;&minus;0.84, 95% CI: &minus;1.15, &minus;0.54; z &thinsp;=&thinsp;&minus;5.43, p &thinsp;&lt;&thinsp;.01), while parent reports indicate a high significant effect (SMD &thinsp;=&thinsp;&minus;0.53, 95% CI: &minus;0.76, &minus;0.31; z &thinsp;=&thinsp;&minus;4.73, p &thinsp;&lt;&thinsp;.01). Results based on the subjects&rsquo; self‐reports indicated a moderate significant effect on the reduction of anxiety (SMD &thinsp;=&thinsp;&minus;0.35, 95% CI: &minus;0.55, &minus;0.15; z &thinsp;=&thinsp;&minus;3.41, p &thinsp;=&thinsp;.001).

Moderators indicated larger effects for treatments that involved parents (SMD &thinsp;=&thinsp;&minus;0.74, 95% CI &minus;1.06, &minus;0.42; z &thinsp;=&thinsp;&minus;4.55, p &thinsp;&lt;&thinsp;.01) than for student‐only interventions (SMD &thinsp;=&thinsp;&minus;0.60, 95% CI &minus;1.03, &minus;0.17; z &thinsp;=&thinsp;&minus;2.73, p &thinsp;&lt;&thinsp;.01). Treatments that were administered individually one‐on‐one (SMD &thinsp;=&thinsp;&minus;1.24, 95% CI &minus;1.75, &minus;0.74; z&thinsp;=&thinsp;&minus;4.87, p &thinsp;&lt;&thinsp;.01), indicated larger effects than for treatments delivered in a group context with peers (SMD &thinsp;=&thinsp;&minus;0.37, 95% CI &minus;0.54, &minus;0.19; z &thinsp;=&thinsp;&minus;4.10, p &thinsp;&lt;&thinsp;.01).

No adverse events were reported. Given the nature of the interventions and the selected outcome measures, the risk of performance and detection bias are generally high, particularly for those studies that used outcome measures based on parent and self‐reports.

**2.7 Authors&rsquo; conclusions**
There is evidence that CBT is an effective behavioral treatment for anxiety in some children and youth with ASD without co‐occurring intellectual disability. Evidence for other psychoeducational interventions is more limited, not just due to the popularity of CBT but also due to the quality of the smaller number of non‐CBT studies available.

While there is evidence that CBT is an effective behavioral treatment for anxiety in some children and youth with ASD, work remains to be done in terms of identifying the characteristics of these interventions that contribute to their effectiveness and identifying the characteristics of participants who are more likely to respond to such interventions.
AU  - Hillman,
AU  - K.
AU  - Dix,
AU  - K.
AU  - Kashfee,
AU  - A.
AU  - Lietz,
AU  - P.
AU  - Trevitt,
AU  - J.
AU  - O&#039;Grady,
AU  - E.
AU  - Uljarevi
AU  - ć,
AU  - M.
AU  - Vivanti,
AU  - G.
AU  - Hedley,
AU  - D.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/cl2.1086
L1  - internal-pdf://2130929430/Hillman.pdf
PY  - 2020
T2  - Campbell Systematic Reviews
TI  - Interventions for anxiety in mainstream school‐aged children with autism spectrum disorder: A systematic review
ER  -
TY  - JOUR
AB  - OBJECTIVE: This systematic review and meta-analysis evaluated the effectiveness of psychoeducational interventions in improving quality of life (QoL) for children with chronic conditions.

METHODS: We identified 25 randomized controlled trials of psychoeducational interventions for children with chronic conditions that reported a QoL outcome and were published 1980-2018. Due to small numbers of interventions in other chronic conditions, comparisons between chronic conditions were limited to 17 studies addressing interventions for asthma and diabetes.

RESULTS: Psychoeducational interventions were associated with a small, statistically significant improvement in QoL (standardized mean difference = 0.14; 95% confidence interval: 0.06-0.23). The effect was significantly larger for asthma interventions compared to diabetes interventions, and in interventions delivered to younger (under 12 years) rather than older children (12 years and over).

CONCLUSIONS: These results suggest that currently evaluated psychoeducational interventions improve QoL for children with asthma but not for children with diabetes. Children with diabetes may require tailored interventions with additional components alongside psychoeducation. Further intervention studies are needed to generalize to other conditions and to draw conclusions about which settings and modes of delivery are most effective in improving QoL.
AD  - Day, Marianne. Department of Psychology, University of Sheffield.Clarke, Sally-Ann. Royal Alexandra Children&#039;s Hospital.Castillo-Eito, Laura. Department of Psychology, University of Sheffield.Rowe, Richard. Department of Psychology, University of Sheffield.
AN  - 32219409
AU  - Day,
AU  - M.
AU  - Clarke,
AU  - S.
AU  - A.
AU  - Castillo-Eito,
AU  - L.
AU  - Rowe,
AU  - R.
DA  - Mar 27
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/jpepsy/jsaa015
DP  - Ovid Technologies
J2  - J Natl Cancer Inst
L1  - internal-pdf://1289599281/Day-2020.pdf
LA  - English
N1  - Using Smart Source ParsingMarDay, MarianneClarke, Sally-AnnCastillo-Eito, LauraRowe, Richardjsaa015
PY  - 2020
SP  - 27
T2  - Journal of the National Cancer Institute
TI  - Psychoeducation for Children with Chronic Conditions: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32219409
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32219409&amp;id=doi:10.1093%2Fjpepsy%2Fjsaa015&amp;issn=0027-8874&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Journal+of+the+National+Cancer+Institute&amp;atitle=Psychoeducation+for+Children+with+Chronic+Conditions%3A+A+Systematic+Review+and+Meta-analysis.&amp;aulast=Day&amp;pid=%3Cauthor%3EDay+M%3C%2Fauthor%3E%3CAN%3E32219409%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://academic.oup.com/jpepsy/article-abstract/45/4/386/5812903?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/jsaa015.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAokwggKFBgkqhkiG9w0BBwagggJ2MIICcgIBADCCAmsGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMXM1mSXo8KqvATQwzAgEQgIICPI-1xvSqBsHdtEveZ9NhiL2koYNZL-2n338fxG_Az_Fp69vazBvj9o6RVC4mRzd3PhjOCzCJZSh8Z7M4CuwiE_4ZBlfP9HuOse1k6SjNTf8bw_HfkhwncEO5d7swGntzNattghsNX25MmetzljNe_MYrD_nj24jO2WAi8w_UE_T4a-HxuU4JLvgNCdVIccoTiXkCJbpnR16EVxQ3kXaLtjbiHLlMpIOTvDd5ClHbUfz8HXF5fG6vg39fe1unQSmmcV8ZZmnKAFugtbY_XMvb_C5aGtU6pf24WKO8bOIccIZOp33dLtMLLs2pQVLgQf1NJOCg7oIoLQ0gjUfq6SF6-PBsy2jLCmle-DzaS-hfufBdabgfaMKeygW8IbiQRs3gPalCnA8wGNjVJNO7Lh5BWevPldOxubBP7JTVSQ9qY-L3RnN6YW_FutUYB32bMcmcAKDm8vZznoqNSZajmFvVKBrAjei-ubO3bXg1OqpMiNRsN3ynoPxaKpHL2XT81G9gwmd96DK5RnP5gLGHO3YX1OcHvWl5OFIcKKgD1UfXypASfdYyo1kviiBuOcnEkaNfJTWhYpwn1pPiMMv3mmD54ZuHRrJa4Q1ElBGt3mxzMHk4QbAjozyU0v-GsZmsuQocWF-k5saCDZFgCDHmUM44_dNj2VQDq0V3pc7wEK2szyixUZ9yTnJs7OZ9iFnLNUwWSqiMnwBkQa_ms5P2l4gEn_QUtMH2NiSZyo_Z6LjpPw6aTfAtmbzvh4X25xa9
VL  - 27
ER  -
TY  - JOUR
AB  - BACKGROUND: Depression among adolescents is rising globally and is the leading cause of illness and disability among adolescents. While antidepressants and psychotherapy are effective, only about 40% of depressed adolescents receive treatments due to lack of professionals and barriers such as cost and personal obstacles including stigma, lack of motivation, and negative perceptions of treatment. Use of alternative and complementary treatments for depression is growing. One such treatment is mindfulness meditation.

OBJECTIVE: We examined the effects of mindfulness interventions on depression among adolescents and explored the moderator effects of participants, methods, and intervention characteristics.

METHODS: We searched 17 databases from their inception to April 2019 to identify studies written in English. Search terms included depress* AND mindful* OR meditat* AND adolescen* OR student*; 29 studies met inclusion criteria. Two researchers independently coded data from all primary studies. Discrepancies were discussed with a third researcher to reach consensus. Using the random effects model, we computed the effect sizes (ESs) of mindfulness interventions on depression using standardized mean differences (Hedge&#039;s g) with 95% confidence intervals (CI). Funnel plot, Q statistics, and I&lt;sup&gt;2&lt;/sup&gt; were used to test the heterogeneity across studies. We examined moderators to explore sources of heterogeneity.

RESULTS: Across 29 studies (N=3688), 1839 adolescents participated in mindfulness interventions; 1849 served as controls. Mean ages ranged from 10.2 to 19.5 years. Mindfulness groups showed reduced depression compared to control groups (g=.14, 95%CI[.01-.28], p&lt;.042). Funded studies showed greater improvement in depression (g=.34, 95%CI[.09-.58], p&lt;.008) compared to unfunded (g=.05, 95%CI[-.12-.22], p&lt;.554). Interestingly, while only two research teams studied mindfulness-based cognitive therapy, they showed trends toward improvement (p=0.09) in depression (g=.76, 95%CI[.18-1.34], p&lt;.010, s=2) compared to adapted mindfulness interventions (g=.13, 95%CI[-.04-.30], p&lt;.140, s=16) or mindfulness-based stress reduction (g=.07, 95%CI[-.16-.29], p&lt;.559, s=11). Mindfulness interventions with individual counseling tended (p=0.09) to improve depression (g=.46, 95%CI[.07-.85], p&lt;.021, s=3) more than without (g=.10, 95%CI[-.04-.24], p&lt;.168, s=26). Depression improved more when follow-up measures occurred further from the intervention (Slope=.002, tau&lt;sup&gt;2&lt;/sup&gt;=.74, Q&lt;sub&gt;between&lt;/sub&gt;=4.10, p=.043, s=29). No quality indicators moderated the ES of mindfulness interventions on depression.

CONCLUSION: Mindfulness interventions are mildly effective interventions to reduce depressive symptoms among adolescents. Clinicians trained in mindfulness interventions might encourage mindfulness meditation as adjunctive/alternative treatment for adolescents with mild or moderate depressive symptoms as well as for at-risk adolescents to prevent depression. Funding, type of mindfulness interventions, individual counseling, and time to follow up were moderators of the effects of mindfulness interventions on depression in adolescents.
AD  - Reangsing, Chuntana. Ph.D. Student, Trudy Busch Valentine, School of Nursing, Saint Louis University, St. Louis, MO, USA. Electronic address: chuntana.reangsing@slu.edu.Punsuwun, Sasinun. Ph.D. Student, Trudy Busch Valentine, School of Nursing, Saint Louis University, St. Louis, MO, USA.Schneider, Joanne Kraenzle. Ph.D. Student, Trudy Busch Valentine, School of Nursing, Saint Louis University, St. Louis, MO, USA.
AN  - 33383273
AU  - Reangsing,
AU  - C.
AU  - Punsuwun,
AU  - S.
AU  - Schneider,
AU  - J.
AU  - K.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.ijnurstu.2020.103848
DP  - Ovid Technologies
J2  - Int J Nurs Stud
L1  - internal-pdf://1958062791/Reangsing-2020.pdf
LA  - English
M3  - Review
N1  - Reangsing, ChuntanaPunsuwun, SasinunSchneider, Joanne KraenzleS0020-7489(20)30339-4
PY  - 2020
SP  - 103848
T2  - International Journal of Nursing Studies
TI  - Effects of mindfulness interventions on depressive symptoms in adolescents: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33383273
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0020748920303394?via%3Dihub
VL  - 115
ER  -
TY  - JOUR
AB  - Research investigating the role of emotion regulation (ER) in the development and treatment of psychopathology has increased in recent years. Evidence suggests that an increased focus on ER in treatment can improve existing interventions. Most ER research has neglected young people, therefore the present meta-analysis summarizes the evidence for existing psychosocial intervention and their effectiveness to improve ER in youth. A systematic review and meta-analysis was conducted according to the PRISMA guidelines. Twenty-one randomized-control-trials (RCTs) assessed changes in ER following a psychological intervention in youth exhibiting various psychopathological symptoms. We found moderate effect sizes for current interventions to decrease emotion dysregulation in youth (g = - 0.46) and small effect sizes to improve emotion regulation (g = 0.36). Significant differences between studies including intervention components, ER measures and populations studied resulted in large heterogeneity. This is the first meta-analysis that summarizes the effectiveness for existing interventions to improve ER in youth. The results suggest that interventions can enhance ER in youth, and that these improvements correlate with improvements in psychopathology. More RCTs including larger sample sizes, different age groups and psychopathologies are needed to increase our understanding of what works for who and when.
AD  - [Moltrecht, Bettina; Deighton, Jessica; Edbrooke-Childs, Julian] UCL, Div Psychol &amp; Language Sci, 26 Bedford Way, London WC1H 0AP, England. [Moltrecht, Bettina; Deighton, Jessica; Edbrooke-Childs, Julian] Anna Freud Natl Ctr Children &amp; Families, London, England. [Patalay, Praveetha] UCL, Ctr Longitudinal Studies, London, England. [Patalay, Praveetha] UCL, MRC Unit Lifelong Hlth &amp; Ageing, London, England.Moltrecht, B (reprint author), UCL, Div Psychol &amp; Language Sci, 26 Bedford Way, London WC1H 0AP, England.; Moltrecht, B (reprint author), Anna Freud Natl Ctr Children &amp; Families, London, England.bettina.moltrecht.16@ucl.ac.uk
AN  - WOS:000516954500001
AU  - Moltrecht,
AU  - B.
AU  - Deighton,
AU  - J.
AU  - Patalay,
AU  - P.
AU  - Edbrooke-Childs,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s00787-020-01498-4
J2  - Eur. Child Adolesc. Psych.
KW  - Emotion regulation
KW  - Psychopathology
KW  - Youth mental health
KW  - Meta-analysis
KW  - Psychological intervention
KW  - cognitive-behavioral therapy
KW  - regulation strategies
KW  - regulation skills
KW  - anxiety symptoms
KW  - mental-disorders
KW  - adolescents
KW  - children
KW  - age
KW  - psychopathology
KW  - dysregulation
KW  - Psychology
KW  - Pediatrics
KW  - Psychiatry
L1  - internal-pdf://3453790459/Moltrecht-Effectiveness of current psychologic.pdf
LA  - English
M3  - Review; Early Access
N1  - ISI Document Delivery No.: KQ5HYTimes Cited: 0Cited Reference Count: 54Moltrecht, Bettina Deighton, Jessica Patalay, Praveetha Edbrooke-Childs, JulianEuropean Union&#039;s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie GrantEuropean Union (EU) [722561]The authors would to like to thank all authors who shared their data and missing information with us when we reached out to them. It was only due to their cooperation that we could conduct the present meta-analysis. Furthermore, we would like to thank Professor Peter Fonagy for his input during the conceptualization of the study and his support in reaching out to the authors. A big thank you goes to Darragh McCashin (DM) for his contribution to the screening and quality check of the selected studies. Funding for this study was provided by the European Union&#039;s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie Grant agreement No. 722561. The European Union&#039;s Horizon 2020 research and innovation programme had no role in the study design, collection, analysis or interpretation of the data, writing the manuscript, or the decision to submit the paper for publication.0SpringerNew york1435-165x
PY  - 2020
SP  - 20
T2  - European Child &amp; Adolescent Psychiatry
TI  - Effectiveness of current psychological interventions to improve emotion regulation in youth: a meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000516954500001
UR  - https://link.springer.com/content/pdf/10.1007/s00787-020-01498-4.pdf
ER  -
TY  - JOUR
AB  - **Purpose:** 
To explore the effects of physical activity (PA) intervention on executive function (EF) and motor skills (MS) among children with attention deficit hyperactivity disorder and/or autism spectrum disorder (ASD). 

**Method(s):** 
Relevant studies were sourced from PubMed, Web of Science, EMBASE, Cochrane Library, CNKI and Wanfang Data. Only randomized controlled trials (RCT) were included based upon the following criteria: (1) participants were children and clinically diagnosed with ADHD/ASD, (2) intervention strategies were identified as chronic physical activity, and (3) EF (e.g., cognitive flexibility) and/or MS (e.g., gross motor skills) were measured at baseline and post-intervention and compared with an eligible control group. 

**Result(s):** 
Eleven studies involving 346 participants were finally identified. PA elicited significant improvements in EF and MS in children with ADHD/ASD. Regarding changes in the EF of participants, PA showed a great improvement in overall EF [standardized mean difference (SMD): 0.90, 95% confidence interval (CI) 0.49-1.30, p &lt; 0.00001], inhibitory control (SMD: 1.30, 95% CI 0.58-2.02, p = 0.0004) and cognitive flexibility (SMD: 0.85, 95% CI 0.42-1.29, p = 0.0001), but no significant improvement in working memory (SMD: 0.28, 95% CI -0.15-0.71, p = 0.20). Significant improvements were also found with respect to gross motor skills (SMD: 0.80, 95% CI 0.30-1.30, p = 0.002), but no significant changes were found in fine motor skills (SMD: 0.30, 95% CI -0.91-1.52, p = 0.62). 

**Conclusion(s):** 
Chronic PA interventions may promote EF and MS in children with ADHD/ASD, especially in inhibitory control, cognitive flexibility, and gross motor skills. However, PA interventions seemed to have insignificant effects on working memory and fine motor skills to children with ADHD/ASD. PROSPERO registration number: CRD42019118622 &copy; Copyright &copy; 2020 Zhang, Liu, Ma and Smith.
AD  - (Zhang, Liu, Smith) Department of Physical Education and Health Education, Springfield College, Springfield, MA, United States (Ma) School of Arts, Beijing Sport University, Beijing, ChinaM. Zhang, Department of Physical Education and Health Education, Springfield College, Springfield, MA, United States. E-mail: mzhang2@springfieldcollege.edu
AN  - 633312759
AU  - Zhang,
AU  - M.
AU  - Liu,
AU  - Z.
AU  - Ma,
AU  - H.
AU  - Smith,
AU  - D.
AU  - M.
DA  - Nov
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fnbeh.2020.564886
DP  - Ovid Technologies
KW  - adhd
KW  - asd
KW  - children
KW  - executive function
KW  - motor skills
KW  - physical activity
KW  - attention deficit disorder
KW  - autism
KW  - child
KW  - Cochrane Library
KW  - controlled study
KW  - Embase
KW  - female
KW  - human
KW  - male
KW  - Medline
KW  - meta analysis
KW  - motor performance
KW  - randomized controlled trial (topic)
KW  - review
KW  - systematic review
KW  - WanFang Database
KW  - Web of Science
KW  - working memory
L1  - internal-pdf://0087534123/Zhang-2020-Chronic Physical Activity for Atten.pdf
LA  - English
M3  - Review
PY  - 2020
T2  - Frontiers in Behavioral Neuroscience
TI  - Chronic Physical Activity for Attention Deficit Hyperactivity Disorder and/or Autism Spectrum Disorder in Children: A Meta-Analysis of Randomized Controlled Trials
UR  - https://www.frontiersin.org/journals/behavioral-neuroscience
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=633312759
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.3389%2Ffnbeh.2020.564886&amp;issn=1662-5153&amp;isbn=&amp;volume=14&amp;issue=&amp;spage=564886&amp;pages=&amp;date=2020&amp;title=Frontiers+in+Behavioral+Neuroscience&amp;atitle=Chronic+Physical+Activity+for+Attention+Deficit+Hyperactivity+Disorder+and%2For+Autism+Spectrum+Disorder+in+Children%3A+A+Meta-Analysis+of+Randomized+Controlled+Trials&amp;aulast=Zhang&amp;pid=%3Cauthor%3EZhang+M.%3C%2Fauthor%3E%3CAN%3E633312759%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/564886/pubmed-zip/.versions/1/.package-entries/fnbeh-14-564886/fnbeh-14-564886.pdf?sv=2018-03-28&amp;sr=b&amp;sig=cYUG%2FrGslZX9qAmiEKSI01dwBM2lYV6omYC4Wj0VXsI%3D&amp;se=2020-12-09T09%3A43%3A12Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fnbeh-14-564886.pdf
VL  - 14 (no pagination)
ER  -
TY  - JOUR
AB  - **Background**
Capturing the scale of child maltreatment is difficult, but few would argue that it is anything less than a global problem which can affect victims&rsquo; health and well‐being throughout their life. Systems of detection, investigation and intervention for maltreated children are the subject of continued review and debate.

**Objectives**
To assess the effectiveness of the formal use of family group decision‐making (FGDM) in terms of child safety, permanence (of child&#039;s living situation), child and family well‐being, and client satisfaction with the decision‐making process.Search MethodsBoth published and unpublished manuscripts were considered eligible for this review. Library staff from Scholarly Information (Brownless Biomedical Library) University of Melbourne, conducted 14 systematic bibliographic searches. Reviewers also checked the reference lists of all relevant articles obtained, and reference lists from previously published reviews. Researchers also hand‐searched 10 relevant journals.

**Selection Criteria**
Study samples of children and young people, aged 0&ndash;18 years, who have been the subject of a child maltreatment investigation, were eligible for this review. Studies had to have used random assignment to create treatment and control groups; or, parallel cohorts in which groups were assessed at the same point in time. Any form of FGDM, used in the course of a child maltreatment investigation or service, was considered an eligible intervention if it involved: a concerted effort to convene family, extended family, and community members; and professionals; and involved a planned meeting with the intention of working collaboratively to develop a plan for the safety well‐being of children; with a focus on family‐centred decision‐making.

**Data Collection and Analysis**
Two review authors independently extracted the necessary data from each study report, using the software application Covidence. Covidence highlighted discrepancies between data extracted by separate reviewers, further analysis was conducted until a consensus was reached on what data were to be included in the review. Two authors also independently conducted analyses of study bias.

**Main Results**
Eighteen eligible study reports were found, providing findings from 15 studies, involving 18 study samples. Four were randomised controlled trials (RCTs; N&thinsp;=&thinsp;941) the remainder employed quasi‐experimental designs with parallel cohorts. Three of the quasi‐experimental studies used prospective evaluations of nonrandomly assigned comparison groups (N&thinsp;=&thinsp;4,368); the rest analysed pre‐existing survey data, child protection case files or court data (N&thinsp;=&thinsp;91,786). The total number of children studied was 97,095. The longest postintervention follow‐up period was 3 years. Only four studies were conducted outside the United States; two in Canada and one in Sweden and one in the Netherlands. The review authors judged there to be a moderate or high risk of bias, in most of the bias categories considered. Only one study referenced a study protocol. Eleven of the fifteen studies were found to have a high likelihood of selection bias (73%). Baseline imbalance bias was deemed to be unlikely in just two studies, and highly likely in nine (60%). Confounding variables were judged to be highly likely in four studies (27%), and contamination bias was judged highly likely in five studies (33%). Researcher allegiance was rated as a high risk in three studies (20%) where the authors argued for the benefits of FGDM within the article, but without supporting references to an appropriate evidence base. Bias from differential diagnostic activity, and funding source bias, were less evident across the evidence reviewed. This review combines findings for eight FGDM outcome measures. Findings from RCTs were available for four outcomes, but none of these, combined in meta‐analysis or otherwise, were statistically significant. Combining findings from the quasi‐experimental studies provided one statistically significant finding, for the reunification of families, favouring FGDM. Ten effect sizes, from nine quasi‐experimental studies, were synthesised to examine effects on the reunification of children with their family or the effect on maintaining in‐home care; in short, the effect FGDM has on keeping families together. There was a high level of heterogeneity between the studies (I2&thinsp;=&thinsp;92%). The overall effect, based on the combination of these studies was positive, small, but statistically significant: odds ratio (OR), 1.69 (confidence interval [CI], 1.03, 2.78). Holinshead&#039;s (2017) RCT also measured the maintenance on in‐home care and reported a similar result: OR, 1.54 (CI, &minus;0.19, 0.66) not statistically significant. The overall effect for continued maltreatment from meta‐analysis of five quasi‐experimental studies, favoured the FGDM group, but was not statistically significant: OR, 0.73 (CI, 0.48, 1.11). The overall combined effect for continued maltreatment, reported in RCTs, favoured the control group. But it was not statistically significant: OR, 1.29 (CI, 0.85, 1.98). Five effect sizes, from nonrandomised studies, were synthesised to examine the effect of FGDM on the number of kinship placements. The overall positive effect based on the combination of these studies was negligible: OR, 1.31 (CI, 0.94, 1.82). Meta‐analysis was not possible with other outcomes. FGDM&#039;s role in expediting case processing and case closures was investigated in six studies, three of which reported findings favouring FGDM, and three which favoured the comparison group. Children&#039;s placement stability was reported in two studies: an RCT&#039;s findings favoured the control, while a quasi‐experimental study&#039;s findings favoured FGDM. Three studies reported findings for service user satisfaction: one had only 30 participants, one reported a statistically significant positive effect for FGDM, the other found no difference between FGDM and a control. Engagement with support services was reported in two studies; neither reported statistically significant findings.

**Authors&#039; Conclusions**
The current evidence base, in this field, is insufficient to draw conclusions about the effectiveness of FGDM. These models of child protection decision‐making may help bring about better outcomes for children at risk, or they may increase the risk of further maltreatment. Further research of rigour, designed to avoid the potential biases of previous evaluations, is needed.
AU  - McGinn,
AU  - T.
AU  - Best,
AU  - P.
AU  - Wilson,
AU  - J.
AU  - Chereni,
AU  - A.
AU  - Kamndaya,
AU  - M.
AU  - Shlonsky,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/cl2.1088
L1  - internal-pdf://2149360207/Mcginn.pdf
PY  - 2020
T2  - Campbell Systematic Reviews
TI  - Family group decision‐making for children at risk of abuse or neglect: A systematic review
ER  -
TY  - JOUR
AB  - This meta-review integrates the current meta-analysis literature on the efficacy of internet- and mobile-based interventions (IMIs) for mental disorders and somatic diseases in children and adolescents. Further, it summarizes the moderators of treatment effects in this age group. Using a systematic literature search of PsycINFO and MEDLINE/PubMed, we identified eight meta-analyses (N = 8,417) that met all inclusion criteria. Current meta-analytical evidence of IMIs exists for depression (range of standardized mean differences, SMDs = .16 to .76; 95 % CI: -.12 to 1.12; k = 3 meta-analyses), anxiety (SMDs = .30 to 1.4; 95 % CI: -.53 to 2.44; k = 5) and chronic pain (SMD = .41; 95 % CI: .07 to .74; k = 1) with predominantly nonactive control conditions (waiting-list; placebo). The effect size for IMIs across mental disorders reported in one meta-analysis is SMD = 1.27 (95 % CI: .96 to 1.59; k = 1), the effect size of IMIs for different somatic conditions is SMD = .49 (95 % CI: .33 to .64; k = 1). Moderators of treatment effects are age (k = 3), symptom severity (k = 1), and source of outcome assessment (k = 1). Quality ratings with the AMSTAR-2-checklist indicate acceptable methodological rigor of meta-analyses included. Taken together, this meta-review suggests that IMIs are efficacious in some health conditions in youths, with evidence existing primarily for depression and anxiety so far. The findings point to the potential of IMIs to augment evidence based mental healthcare for children and adolescents.
AD  - Domhardt, Matthias. Department of Clinical Psychology and Psychotherapy, University of Ulm, Germany.Steubl, Lena. Department of Clinical Psychology and Psychotherapy, University of Ulm, Germany.Baumeister, Harald. Department of Clinical Psychology and Psychotherapy, University of Ulm, Germany.
AN  - 30422059
AU  - Domhardt,
AU  - M.
AU  - Steubl,
AU  - L.
AU  - Baumeister,
AU  - H.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1024/1422-4917/a000625
DP  - Ovid Technologies
J2  - Z Kinder Jugendpsychiatr Psychother
KW  - Adolescent
KW  - Anxiety/th [Therapy]
KW  - *Anxiety Disorders/th [Therapy]
KW  - *Cell Phone
KW  - Child
KW  - Depression/th [Therapy]
KW  - *Depressive Disorder/th [Therapy]
KW  - Humans
KW  - *Internet
KW  - Treatment Outcome
L1  - internal-pdf://1333959300/Domhardt-2020-Internet- and Mobile-Based Inter.pdf
LA  - English
M3  - Meta-Analysis
Review
N1  - Domhardt, MatthiasSteubl, LenaBaumeister, Harald
PY  - 2020
SP  - 33-46
T2  - Zeitschrift fur Kinder-und Jugendpsychiatrie und Psychotherapie
TI  - Internet- and Mobile-Based Interventions for Mental and Somatic Conditions in Children and Adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=30422059
UR  - https://econtent.hogrefe.com/doi/pdf/10.1024/1422-4917/a000625
VL  - 48
ER  -
TY  - JOUR
AB  - Computer-based training has attracted increasing attention from researchers in recent years. Several studies have found that computer-based training resulted in improved executive functions (EFs) in adults. However, it remains controversial whether children can benefit from computer-based training and what moderator could influence the training effects. The focus of the present meta-analysis was to examine the effects of computer-based training on EFs in children: working memory, cognitive flexibility, and inhibitory control. A thorough search of published work yielded a sample of 36 studies with 216 effect sizes. The results indicated that computer-based training showed moderate training effects on improving EFs in children (g = 0.35, k = 36, p &lt; 0.001), while training effects of working memory were significantly higher. Furthermore, we found near-transfer effects were marginally significantly higher than far-transfer effects. The standard training method was significantly more effective than training with game elements. In computer-based training, typically developing children had significantly better training effects than atypically developing children. Some additional factors, such as the number of training sessions and age, also modulated the training effects. In conclusion, the present study investigated the effects and moderators of computer-based training for children&#039;s EFs. The results provided evidence that computer-based training (especially standard training) may serve as an efficient way to improve EFs in children (especially typically developing individuals). We also discussed some directions for future computer-based training studies.
AN  - WOS:000596846900001
AU  - Cao,
AU  - Y.
AU  - F.
AU  - Huang,
AU  - T.
AU  - Huang,
AU  - J.
AU  - P.
AU  - Xie,
AU  - X.
AU  - C.
AU  - Wang,
AU  - Y.
DA  - NOV 26
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3389/fpsyg.2020.580329
L1  - internal-pdf://0875067625/Cao-2020.pdf
PY  - 2020
T2  - FRONTIERS IN PSYCHOLOGY
TI  - Effects and Moderators of Computer-Based Training on Children&#039;s Executive Functions: A Systematic Review and Meta-Analysis
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/580329/pubmed-zip/.versions/1/.package-entries/fpsyg-11-580329/fpsyg-11-580329.pdf?sv=2018-03-28&amp;sr=b&amp;sig=YoKX2%2B0%2BuHOaMKNmRiWaIw%2BId1T6DWkAOGycVzsEn48%3D&amp;se=2021-06-17T11%3A30%3A55Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyg-11-580329.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - **Background**
Uncertainty exists about the optimal point at which multi‐component fortifier should be added to human milk for promoting growth in preterm infants. The most common practice is to start fortification when the infant&rsquo;s daily enteral feed volume reaches 100 mL/kg body weight. Another approach is to commence fortification earlier, in some cases as early as the first enteral feed. Early fortification of human milk could increase nutrient intake and growth rates but may increase the risk of feed intolerance and necrotising enterocolitis (NEC).

**Objectives**
To assess effects on growth and safety of early fortification of human milk versus late fortification in preterm infants. 

To assess whether effects vary based upon gestational age (&le; 27 weeks; 28 to 31 weeks; &ge; 32 weeks), birth weight (&lt; 1000 g; 1000 to 1499 g; &ge; 1500 g), small or appropriate for gestational age, or type of fortifier (bovine milk‐based human milk fortifier (HMF); human milk‐based HMF; formula powder)

**Search methods**
We used the standard strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2019, Issue 8); OVID MEDLINE (R) and Epub Ahead of Print, In‐Process &amp; Other Non‐Indexed Citations, Daily and Versions (R) (1946 to 15 August 2019); MEDLINE via PubMed (1 August 2018 to 15 August 2019) for the previous year; and the Cumulative Index to Nursing and Allied Health Literatue (CINAHL) (1981 to 15 August 2019). We searched clinical trials databases and reference lists of included studies.

**Selection criteria**
We included randomised controlled trials that compared early versus late fortification of human milk in preterm infants. We defined early fortification as fortification started at &lt; 100 mL/kg/d enteral feed volume or &lt; 7 days postnatal age, and late fortification as fortification started at &ge; 100 mL/kg/d feeds or &ge; 7 days postnatal age.

**Data collection and analysis**
Both review authors assessed trial eligibility and risk of bias and independently extracted data. We analysed treatment effects in individual trials, and we reported risk ratio (RR) for dichotomous data and mean difference (MD) for continuous data, with respective 95% confidence intervals (CIs). We used the GRADE approach to assess the certainty of evidence.

**Main results**
We included two trials with a total of 237 infants. All participants were very low birth weight infants (birth weight &lt; 1500 g). Early fortification was started at 20 mL/kg/d enteral feeds in one study and 40 mL/kg/d in the other study. Late fortification was started at 100 mL/kg/d feeds in both studies. One study used bovine milk‐based fortifier, and the other used human milk‐based fortifier.Meta‐analysis showed that early fortification may have little or no effect on growth outcomes including time to regain birth weight (MD ‐0.06 days, 95% CI ‐1.32 to 1.20 days), linear growth (MD 0.10 cm/week, 95% CI ‐0.03 to 0.22 cm/week), or head growth (MD ‐0.01 cm/week, 95% CI ‐0.07 to 0.06 cm/week) during the initial hospitalisation period. Early fortification may have little or no effect on the risk of NEC (MD ‐0.01, 95% CI ‐0.07 to 0.06). The certainty of evidence was low for these outcomes due to risk of bias (lack of blinding) and imprecision (small sample size).Early fortification may have little or no effect on incidence of surgical NEC, time to reach full enteral feeds, extrauterine growth restriction at discharge, proportion of infants with feed interruption episodes, duration of total parenteral nutrition (TPN), duration of central venous line usage, or incidence of invasive infection, all‐cause mortality, and duration of hospital stay. The certainty of evidence was low for these outcomes due to risk of bias (lack of blinding) and imprecision (small sample size).We did not have data for other outcomes such as subsequent weight gain after birth weight is regained, parenteral nutrition‐associated liver disease, postdischarge growth, and neurodevelopmental outcomes.

**Authors&#039; conclusions**
Available evidence is insufficient to support or refute early fortification of human milk in preterm infants. Further large trials would be needed to provide data of sufficient quality and precision to inform policy and practice.
AU  - Thanigainathan,
AU  - S.
AU  - Abiramalatha,
AU  - T.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD013392.pub2
L1  - internal-pdf://2026190120/Thanigainathan_et_al-2020-Cochrane_Database_of.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Early fortification of human milk versus late fortification to promote growth in preterm infants
ER  -
TY  - JOUR
AB  - OBJECTIVES: This systematic review (SR) synthesizes the literature on behavioral, pharmacologic, and combined interventions for adolescents ages 12 to 20 years with problematic substance use or substance use disorder. We included interventions designed to achieve abstinence, reduce use quantity and frequency, improve functional outcomes, and reduce substance-related harms.

DATA SOURCES: We conducted literature searches in MEDLINE, the Cochrane CENTRAL Trials Registry, Embase, CINAHL, and PsycINFO to identify primary studies meeting eligibility criteria through November 1, 2019.

REVIEW METHODS: Studies were extracted into the Systematic Review Data Repository. We categorized interventions into seven primary intervention components: motivational interviewing (MI), family focused therapy (Fam), cognitive behavioral therapy (CBT), psychoeducation, contingency management (CM), peer group therapy, and intensive case management. We conducted meta-analyses of comparative studies and evaluated the strength of evidence (SoE). The PROSPERO protocol registration number is CRD42018115388.

RESULTS: The literature search yielded 33,272 citations, of which 118 studies were included. Motivational interviewing reduced heavy alcohol use days by 0.7 days/month, alcohol use days by 1.2 days/month, and overall substance use problems by a standardized mean difference of 0.5, compared with treatment as usual. Brief MI did not reduce cannabis use days (net mean difference of 0). Across multiple intensive interventions, Fam was most effective, reducing alcohol use days by 3.5 days/month compared with treatment as usual. No intensive interventions reduced cannabis use days. Pharmacologic treatment of opioid use disorder led to a more than 4 times greater likelihood of abstinence with extended courses (2 to 3 months) of buprenorphine compared to short courses (14 to 28 days).

CONCLUSIONS: Brief interventions: MI reduces heavy alcohol use (low SoE), alcohol use days (moderate SoE), and substance use-related problems (low SoE) but does not reduce cannabis use days (moderate SoE). Nonbrief interventions: Fam may be most effective in reducing alcohol use (low SoE). More research is needed to identify other effective intensive behavioral interventions for alcohol use disorder. Intensive interventions did not appear to decrease cannabis use (low SoE). Some interventions (CBT, CBT+MI, and CBT+MI+CM) were associated with increased cannabis use (low SoE). Both MI and CBT reduce combined alcohol and other drug use (low SoE). Combined CBT+MI reduces illicit drug use (low SoE). Subgroup analyses of interest (male vs. female, racial and ethnic minorities, socioeconomic status, and family characteristics) were sparse, precluding conclusions regarding differential effects. Pharmacological interventions: longer courses of buprenorphine (2-3 months) are more effective than shorter courses (14-28 days) to reduce opioid use and achieve abstinence (low SoE). SRs in the college settings support use of brief interventions for students with any use, heavy or problematic use. More research is needed to identify the most effective combinations of behavioral and pharmacologic treatments for opioid, alcohol, and cannabis use disorders.
AN  - 32479039
AU  - Steele,
AU  - D.
AU  - W.
AU  - Becker,
AU  - S.
AU  - J.
AU  - Danko,
AU  - K.
AU  - J.
AU  - Balk,
AU  - E.
AU  - M.
AU  - Saldanha,
AU  - I.
AU  - J.
AU  - Adam,
AU  - G.
AU  - P.
AU  - Bagley,
AU  - S.
AU  - M.
AU  - Friedman,
AU  - C.
AU  - Spirito,
AU  - A.
AU  - Scott,
AU  - K.
AU  - Ntzani,
AU  - E.
AU  - E.
AU  - Saeed,
AU  - I.
AU  - Smith,
AU  - B.
AU  - Popp,
AU  - J.
AU  - Trikalinos,
AU  - T.
AU  - A.
DA  - 05
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /books/NBK557291/
DP  - Ovid Technologies
J2  - Agency for Healthcare Research and Quality (US)
L1  - internal-pdf://2206576442/Steele-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source Parsing20-EHC014Steele, Dale W.Becker, Sara J.Danko, Kristin J.Balk, Ethan M.Saldanha, Ian J.Adam, Gaelen P.Bagley, Sarah M.Friedman, CatherineSpirito, AnthonyScott, KelliNtzani, Evangelia E.Saeed, ImanSmith, BryantPopp, JonahTrikalinos, Thomas A.
PY  - 2020
T2  - Agency for Healthcare Research and Quality
TI  - Interventions for Substance Use Disorders in Adolescents: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32479039
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32479039&amp;id=doi:&amp;issn=&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=%3D%3D%3D&amp;atitle=Interventions+for+Substance+Use+Disorders+in+Adolescents%3A+A+Systematic+Review&amp;aulast=Steele&amp;pid=%3Cauthor%3ESteele+DW%3C%2Fauthor%3E%3CAN%3E32479039%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - This study is the first to systematically review and quantify the effects of physical activity on brain structure and neurophysiological functioning in children. Electronic data bases were searched for relevant studies. Studies that met the following criteria were included: (1) used an RCT or cross-over design, (2) examined the effects of physical activity on brain structure and/or neurophysiological functioning, (3) included children (5-12 years old) (4) included a control group (RCTs) or control condition (cross-over trials). A total of 26 and 20 studies were included in the systematic review and meta-analysis, respectively, representing and accompanying 973 and 782 unique children. Main analyses were separated for short-term and long-term physical activity and for effects on brain structure and neurophysiological functioning with a distinction between children from healthy and clinical populations. We found evidence for significant beneficial effects of long-term physical activity on neurophysiological functioning (d = 0.39, p &lt; 0.001). In addition, short-term physical activity may induce changes in neurophysiological functioning (d = 0.32, p = 0.044), although this evidence showed limited robustness. No meta-analytic evidence was found for positive effects on brain structure. The results underline the importance of physical activity for brain development in children.
AN  - WOS:000582464400012
AU  - Meijer,
AU  - A.
AU  - Konigs,
AU  - M.
AU  - Vermeulen,
AU  - G.
AU  - T.
AU  - Visscher,
AU  - C.
AU  - Bosker,
AU  - R.
AU  - J.
AU  - Hartman,
AU  - E.
AU  - Oosterlaan,
AU  - J.
AU  - Oosterlaan,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.dcn.2020.100828
L1  - internal-pdf://3848044964/Meijer-2020.pdf
N1  - Meijer, Anna Konigs, Marsh Vermeulen, Gerben T. Visscher, Chris Bosker, Roel J. Hartman, Esther Oosterlaan, Jaap Oosterlaan, JaapMeijer, Anna/0000-0002-7354-78621878-9307
PY  - 2020
T2  - Developmental Cognitive Neuroscience
TI  - The effects of physical activity on brain structure and neurophysiological functioning in children: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000582464400012
VL  - 45
ER  -
TY  - JOUR
AB  - **Objective:** 
To evaluate the efficacy and safety of melatonin in the treatment of sleep onset insomnia in children and adolescents. 

**Methods:** 
Electronic databases and bibliographies of relevant reports were searched for randomized, placebo-controlled, clinical trials that used melatonin in children and adolescents with sleep onset insomnia. The quality of the included studies was assessed by the Cochrane Collaboration&#039;s risk-of-bias method. The mean differences (MD) and the odds ratios (OR) with 95% confidence interval (CI) were estimated by a random-effects model. Primary outcomes were sleep onset time (SOT), drop-out for all causes and drop-out for adverse events. Secondary outcomes included dim light melatonin onset (DLMO), sleep onset latency (SOL), total sleep time (TST), light-off time, and wake-up time. 

**Results:** 
Seven trials with 387 participants were finally included after a systematic search. The overall quality of the included studies was low to moderate. SOT in patients receiving melatonin advanced more than patients receiving placebo (MD = -0.62 h, 95% CI -0.80, -0.45), as well as DLMO (MD = -0.82 h, 95% CI -1.23, -0.41). No differences were found in the outcome of drop-out for all causes (OR = 1.51, 95% CI 0.57, 4.05) or drop-out for adverse events (OR = 3.35, 95% CI 0.13, 86.03). Severe adverse events, migraine, and mild generalized epilepsy were reported in two cases. SOL decreased and TST increased, MD = -0.36 h (95% CI -0.49, -0.24) and MD = 0.38 h (95% CI 0.09, 0.66), respectively. Light-off time and wake-up time did not differ significantly. 

**Conclusions:** 
Melatonin was an effective and tolerable drug in the short-term treatment of sleep onset insomnia in children and adolescents. More studies, especially in adolescents, are needed to investigate the efficacy and safety of melatonin. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - Xiao, Mingzhao: xmz.2004@163.com; Zhou, Xinyu: xinyu973@126.comXiao, Mingzhao: Department of Urology, First Affiliated Hospital, Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing, China, 400016, xmz.2004@163.comWei, Sha: Department of Psychiatry, First Affiliated Hospital, Chongqing Medical University, Chongqing, ChinaSmits, Marcel G.: Department of Sleep-wake Disorders and Chronobiology, Gelderse Valley Hospital Ede, NetherlandsTang, Xiangdong: Sleep Medicine Center, West China Hospital, Sichuan University, Sichuan, ChinaKuang, Li: Department of Psychiatry, First Affiliated Hospital, Chongqing Medical University, Chongqing, ChinaMeng, Huaqing: Department of Psychiatry, First Affiliated Hospital, Chongqing Medical University, Chongqing, ChinaNi, Shifen: Department of Psychiatry, First Affiliated Hospital, Chongqing Medical University, Chongqing, ChinaXiao, Mingzhao: Department of Urology, First Affiliated Hospital, Chongqing Medical University, Chongqing, ChinaZhou, Xinyu: Department of Psychiatry, First Affiliated Hospital, Chongqing Medical University, Chongqing, China
AN  - 2020-26768-002
AU  - Wei,
AU  - Sha
AU  - Smits,
AU  - Marcel
AU  - G.
AU  - Tang,
AU  - Xiangdong
AU  - Kuang,
AU  - Li
AU  - Meng,
AU  - Huaqing
AU  - Ni,
AU  - Shifen
AU  - Xiao,
AU  - Mingzhao
AU  - Zhou,
AU  - Xinyu
DA  - Apr
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.sleep.2019.02.017
DP  - Ovid Technologies
KW  - Sleep onset insomnia, Melatonin, Efficacy, Safety
KW  - *Drug Therapy
KW  - *Insomnia
KW  - *Melatonin
KW  - *Sleep Onset
KW  - Treatment Effectiveness Evaluation
KW  - Patient Safety
KW  - Clinical Psychopharmacology [3340]
KW  - Human
L1  - internal-pdf://0336397042/Wei-2020.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
SP  - 1-8
T2  - Sleep Medicine
TI  - Efficacy and safety of melatonin for sleep onset insomnia in children and adolescents: A meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-26768-002
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.sleep.2019.02.017&amp;issn=1389-9457&amp;isbn=&amp;volume=68&amp;issue=&amp;spage=1&amp;pages=1-8&amp;date=2020&amp;title=Sleep+Medicine&amp;atitle=Efficacy+and+safety+of+melatonin+for+sleep+onset+insomnia+in+children+and+adolescents%3A+A+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Wei&amp;pid=%3Cauthor%3EWei%2C+Sha%3C%2Fauthor%3E%3CAN%3E2020-26768-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/abs/pii/S1389945718307561?via%3Dihub
VL  - 68
ER  -
TY  - JOUR
AB  - Anxiety disorders are common mental health problems amongst youth with harmful impacts often extending into adulthood. Mindfulness-based interventions (MBIs) have become increasingly popular for addressing mental health issues, particularly in schools; however, it remains unclear how effective they are for reducing youth anxiety. 

This meta-analysis aimed to evaluate the efficacy and effect moderators of MBIs on anxiety outcomes in children and adolescents. Eligible studies were published randomised controlled trials (RCTs) of MBIs conducted with participants aged 18 years or younger, investigating anxiety outcomes using a well-validated anxiety scale. 

A systematic search of RCTs published through to February 2019 identified 20 studies for inclusion (n = 1582). A random effects model was used to synthesise MBI effects. Stratified meta-analyses as well as individual, random effects meta-regressions were performed to examine how effects varied by age group, intervention setting, control type, research location, and intervention dosage. Although, across all studies, there was a small beneficial effect of MBIs on anxiety post treatment (d = 0.26), this was significantly moderated by research location, with RCTs conducted in Iran producing large effects (d = 1.25), and RCTs conducted in Western countries demonstrating no significant beneficial effect compared to controls (very small, d = 0.05). Effects were non-significant at follow-up assessment points. Post-treatment effects were significant for MBIs conducted with children (d = 0.41) and for MBIs when compared to passive controls (d = 0.33), but non-significant for adolescents (d = 0.21), for MBIs conducted in schools (d = 0.30) and in clinics (d = 0.13), and when MBIs were compared to active controls (d = 0.12). 

Results suggest that MBIs are likely to have a small to medium, yet temporary effect in reducing anxiety symptoms in children (not adolescents), but amongst Western youth populations the most likely outcome, from RCTs to date, is that MBIs produce no beneficial effect in anxiety reduction. Results revealed a lack of evidence to support investment in school-based MBIs to address youth anxiety.
AD  - Odgers, Katarzyna. Centre for Emotional Health, Macquarie University, Sydney, NSW, 2109, Australia.Odgers, Katarzyna. Department of Psychology, Macquarie University, Sydney, NSW, 2109, Australia.Dargue, Nicole. Centre for Emotional Health, Macquarie University, Sydney, NSW, 2109, Australia.Dargue, Nicole. Department of Psychology, Macquarie University, Sydney, NSW, 2109, Australia.Creswell, Cathy. Department of Psychology, Macquarie University, Sydney, NSW, 2109, Australia.Creswell, Cathy. Departments of Experimental Psychology and Psychiatry, University of Oxford, Oxford, UK.Jones, Michael P. Centre for Emotional Health, Macquarie University, Sydney, NSW, 2109, Australia.Jones, Michael P. Department of Psychology, Macquarie University, Sydney, NSW, 2109, Australia.Hudson, Jennifer L. Centre for Emotional Health, Macquarie University, Sydney, NSW, 2109, Australia. jennie.hudson@mq.edu.au.Hudson, Jennifer L. Department of Psychology, Macquarie University, Sydney, NSW, 2109, Australia. jennie.hudson@mq.edu.au.
AN  - 32583200
AU  - Odgers,
AU  - K.
AU  - Dargue,
AU  - N.
AU  - Creswell,
AU  - C.
AU  - Jones,
AU  - M.
AU  - P.
AU  - Hudson,
AU  - J.
AU  - L.
DA  - Jun 25
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s10567-020-00319-z
DP  - Ovid Technologies
J2  - Clin Child Fam Psychol Rev
L1  - internal-pdf://3947146722/Odgers-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingJunOdgers, KatarzynaDargue, NicoleCreswell, CathyJones, Michael PHudson, Jennifer L
PY  - 2020
SP  - 25
T2  - Clinical Child &amp; Family Psychology Review
TI  - The Limited Effect of Mindfulness-Based Interventions on Anxiety in Children and Adolescents: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32583200
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32583200&amp;id=doi:10.1007%2Fs10567-020-00319-z&amp;issn=1096-4037&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Clinical+Child+%26+Family+Psychology+Review&amp;atitle=The+Limited+Effect+of+Mindfulness-Based+Interventions+on+Anxiety+in+Children+and+Adolescents%3A+A+Meta-Analysis.&amp;aulast=Odgers&amp;pid=%3Cauthor%3EOdgers+K%3C%2Fauthor%3E%3CAN%3E32583200%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10567-020-00319-z
UR  - https://link.springer.com/content/pdf/10.1007/s10567-020-00319-z.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - **Background**
The prevalence of substance use, both prescribed and non‐prescribed, is increasing in many areas of the world. Substance use by women of childbearing age contributes to increasing rates of neonatal abstinence syndrome (NAS). Neonatal opioid withdrawal syndrome (NOWS) is a newer term describing the subset of NAS related to opioid exposure. Non‐pharmacological care is the first‐line treatment for substance withdrawal in newborns. Despite the widespread use of non‐pharmacological care to mitigate symptoms of NAS, there is not an established definition of, and standard for, non‐pharmacological care practices in this population. Evaluation of safety and efficacy of non‐pharmacological practices could provide clear guidance for clinical practice.

**Objectives**
To evaluate the safety and efficacy of non‐pharmacological treatment of infants at risk for, or having symptoms consistent with, opioid withdrawal on the length of hospitalization and use of pharmacological treatment for symptom management.

Comparison 1: in infants at risk for, or having early symptoms consistent with, opioid withdrawal, does non‐pharmacological treatment reduce the length of hospitalization and use of pharmacological treatment?

Comparison 2: in infants receiving pharmacological treatment for symptoms consistent with opioid withdrawal, does concurrent non‐pharmacological treatment reduce duration of pharmacological treatment, maximum and cumulative doses of opioid medication, and length of hospitalization?

**Search methods**
We used the standard search strategy of Cochrane Neonatal to search CENTRAL (2019, Issue 10); Ovid MEDLINE; and CINAHL on 11 October 2019. We also searched clinical trials databases and the reference lists of retrieved articles for randomized controlled trials (RCTs), quasi‐RCTs, and cluster trials.

**Selection criteria**
We included trials comparing single or bundled non‐pharmacological interventions to no non‐pharmacological treatment or different single or bundled non‐pharmacological interventions. We assessed non‐pharmacological interventions independently and in combination based on sufficient similarity in population, intervention, and comparison groups studied. We categorized non‐pharmacological interventions as: modifying environmental stimulation, feeding practices, and support of the mother‐infant dyad. We presented non‐randomized studies identified in the search process narratively.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane. We used the GRADE approach to assess the certainty of evidence. Primary outcomes in infants at risk for, or having early symptoms consistent with, opioid withdrawal included length of hospitalization and pharmacological treatment with one or more doses of opioid or sedative medication. Primary outcomes in infants receiving opioid treatment for symptoms consistent with opioid withdrawal included length of hospitalization, length of pharmacological treatment with opioid or sedative medication, and maximum and cumulative doses of opioid medication.

**Main results**
We identified six RCTs (353 infants) in which infants at risk for, or having symptoms consistent with, opioid withdrawal participated between 1975 and 2018. We identified no RCTs in which infants receiving opioid treatment for symptoms consistent with opioid withdrawal participated. The certainty of evidence for all outcomes was very low to low. We also identified and excluded 34 non‐randomized studies published between 2005 and 2018, including 29 in which infants at risk for, or having symptoms consistent with, opioid withdrawal participated and five in which infants receiving opioid treatment for symptoms consistent with opioid withdrawal participated. We identified seven preregistered interventional clinical trials that may qualify for inclusion at review update when complete.

Of the six RCTs, four studies assessed modifying environmental stimulation in the form of a mechanical rocking bed, prone positioning, non‐oscillating waterbed, or a low‐stimulation nursery; one study assessed feeding practices (comparing 24 kcal/oz to 20 kcal/oz formula); and one study assessed support of the maternal‐infant dyad (tailored breastfeeding support).

There was no evidence of a difference in length of hospitalization in the one study that assessed modifying environmental stimulation (mean difference [MD) &ndash;1 day, 95% confidence interval [CI) &ndash;2.82 to 0.82; 30 infants; very low‐certainty evidence) and the one study of support of the maternal‐infant dyad (MD &ndash;8.9 days, 95% CI &ndash;19.84 to 2.04; 14 infants; very low‐certainty evidence). No studies of feeding practices evaluated the length of hospitalization.

There was no evidence of a difference in use of pharmacological treatment in three studies of modifying environmental stimulation (typical risk ratio [RR) 1.00, 95% CI 0.86 to 1.16; 92 infants; low‐certainty evidence), one study of feeding practices (RR 0.92, 95% CI 0.63 to 1.33; 49 infants; very low‐certainty evidence), and one study of support of the maternal‐infant dyad (RR 0.50, 95% CI 0.13 to 1.90; 14 infants; very low‐certainty evidence).

Reported secondary outcomes included neonatal intensive care unit (NICU) admission, days to regain birth weight, and weight nadir. One study of support of the maternal‐infant dyad reported NICU admission (RR 0.50, 95% CI 0.13 to 1.90; 14 infants; very low‐certainty evidence). One study of feeding practices reported days to regain birth weight (MD 1.10 days, 95% CI 2.76 to 0.56; 46 infants; very low‐certainty evidence). One study that assessed modifying environmental stimulation reported weight nadir (MD &ndash;0.28, 95% CI &ndash;1.15 to 0.59; 194 infants; very low‐certainty evidence) and one study of feeding practices reported weight nadir (MD &ndash;0.8, 95% CI &ndash;2.24 to 0.64; 46 infants; very low‐certainty evidence).

**Authors&#039; conclusions**
We are uncertain whether non‐pharmacological care for opioid withdrawal in newborns affects important clinical outcomes including length of hospitalization and use of pharmacological treatment based on the six included studies. The outcomes identified for this review were of very low‐ to low‐certainty evidence. Combined analysis was limited by heterogeneity in study design and intervention definitions as well as the number of studies. Many prespecified outcomes were not reported. Although caregivers are encouraged by experts to optimize non‐pharmacological care for opioid withdrawal in newborns prior to initiating pharmacological care, we do not have sufficient evidence to inform specific clinical practices. Larger well‐designed studies are needed to determine the effect of non‐pharmacological care for opioid withdrawal in newborns.
AU  - Pahl,
AU  - A.
AU  - Young,
AU  - L.
AU  - Buus-Frank,
AU  - ME.
AU  - Marcellus,
AU  - L.
AU  - Soll,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD013217.pub2
L1  - internal-pdf://3353699852/Pahl_et_al-2020-Cochrane_Database_of_Systemati.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Non-pharmacological care for opioid withdrawal in newborns
ER  -
TY  - JOUR
AB  - **Objectives** 
To examine the effectiveness of social skills training (SST) for juvenile offenders and for whom and under which conditions SSTs are the most effective. 

**Methods**
 Multilevel meta-analyses were conducted to examine the effectiveness of juvenile offender SST compared to no/placebo treatment and alternative treatment on offending, externalizing problems, social skills, and internalizing problems. 

**Results** 
Beneficial effects were only found for offending and social skills compared to no/placebo treatment. Compared to alternative treatment, small effects on only reoffending were found. Moderator analyses yielded larger effects on offending, with larger post-treatment effects on social skills. Effects on externalizing behavior were only reported in the USA, and effects on social skills were larger when the outcomes were reported through self-report. 

**Conclusions** 
SST may be a too generic treatment approach to reduce juvenile delinquency, because dynamic risk factors for juvenile offending are only partially targeted in SST.
AN  - WOS:000518077400001
AU  - van
AU  - der
AU  - Stouwe,
AU  - T.
AU  - Gubbels,
AU  - J.
AU  - Castenmiller,
AU  - Y.
AU  - L.
AU  - van
AU  - der
AU  - Zouwen,
AU  - M.
AU  - Asscher,
AU  - J.
AU  - J.
AU  - Hoeve,
AU  - M.
AU  - van
AU  - der
AU  - Laan,
AU  - P.
AU  - H.
AU  - Stams,
AU  - Gjjm
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s11292-020-09419-w
L1  - internal-pdf://1076861891/van der Stouwe-The effectiveness of social ski.pdf
N1  - Van der Stouwe, Trudy Gubbels, Jeanne Castenmiller, Yvonne L. Van der Zouwen, Marion Asscher, Jessica J. Hoeve, Machteld van der Laan, Peter H. Stams, Geert Jan J. M.Hoeve, Machteld/0000-0002-4487-53651572-8315
PY  - 2020
T2  - Journal of Experimental Criminology
TI  - The effectiveness of social skills training (SST) for juvenile delinquents: a meta-analytical review
UR  - &lt;Go to ISI&gt;://WOS:000518077400001
UR  - https://link.springer.com/content/pdf/10.1007/s11292-020-09419-w.pdf
ER  -
TY  - JOUR
AB  - **Background:** 
Digital interventions are proposed as one way by which effective treatments for self-harm and suicidal ideation may be improved and their scalability enhanced. Mobile devices offer a potentially powerful medium to deliver evidence-based interventions with greater specificity to the individual when the intervention is needed. The recent proliferation of publicly available mobile apps designed for suicide prevention underlines the need for robust evidence to promote safe practice. Objective: This review aimed to examine the effectiveness of currently available mobile health (mHealth) technology tools in reducing suicide-specific outcomes. 

**Methods:** 
The following databases were searched: Cochrane Central Register of Controlled Trials (The Cochrane Library), MEDLINE, EMBASE, PsycINFO, and relevant sources of gray literature. All published and unpublished randomized controlled trials (RCTs), pseudo-RCTs, and pre-post observational studies that evaluated the effectiveness of mHealth technology in suicide prevention delivered via mobile computing and communication technology were included. Studies were included if they measured at least one suicide outcome variable (ie, suicidal ideation, suicidal intent, nonsuicidal self-injurious behavior, and suicidal behavior). A total of 2 review authors independently extracted data and assessed study suitability, in accordance with the Cochrane Collaboration Risk of Bias Tool, on July 31, 2018. Owing to the heterogeneity of outcomes found across studies, results were not amenable for pooled synthesis, and a meta-analysis was not performed. A narrative synthesis of the available research is presented here. 

**Results:** 
A total of 7 studies met criteria for inclusion. Four published articles that reported on the effectiveness of the following mobile phone apps were included: iBobbly, Virtual Hope Box, BlueIce, and Therapeutic Evaluative Conditioning. Results demonstrated some positive impacts for individuals at elevated risk of suicide or self-harm, including reductions in depression, psychological distress, and self-harm and increases in coping self-efficacy. None of the apps evaluated demonstrated the ability to significantly decrease suicidal ideation compared with a control condition. In addition, 3 unpublished and recently completed trials also met criteria for inclusion in the review. 

**Conclusions:** 
Further research is needed to evaluate the efficacy of stand-alone mHealth technology-based interventions in suicide prevention. The small number of studies reported in this review tentatively indicate that such tools may have a positive impact on suicide-specific outcomes. Future mHealth intervention evaluations would benefit from addressing the following 3 main methodological limitations : (1) heterogeneity of outcomes: a lack of standardized measurement of suicide outcomes across studies; (2) ecological validity: the tendency to exclude potential participants because of the elevated suicide risk may reduce generalizability within clinical settings; and (3) app regulation and definition: the lack of a standardized classification system for mHealth intervention type points to the need for better definition of the scope of such technologies to promote safe practice.
AD  - [Melia, Ruth; Francis, Kady; Bogue, John; O&#039;Sullivan, Mary] Natl Univ Ireland Galway, Sch Psychol, Arts Millennium Bldg, Galway H91 TK33, Ireland. [Melia, Ruth] Hlth Serv Execut Midwest, Psychol Dept, Ennis, Ireland. [Hickey, Emma] Hlth Serv Execut Midwest, Psychol Dept, Limerick, Ireland. [Duggan, Jim] Natl Univ Ireland Galway, Discipline Informat Technol, Galway, Ireland. [Young, Karen] Natl Univ Ireland Galway, Insight Ctr Discipline Informat Technol, Galway, Ireland.Melia, R (reprint author), Natl Univ Ireland Galway, Sch Psychol, Arts Millennium Bldg, Galway H91 TK33, Ireland.ruth.melia@hse.ie
AN  - WOS:000507919000001
AU  - Melia,
AU  - R.
AU  - Francis,
AU  - K.
AU  - Hickey,
AU  - E.
AU  - Bogue,
AU  - J.
AU  - Duggan,
AU  - J.
AU  - O&#039;Sullivan,
AU  - M.
AU  - Young,
AU  - K.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.2196/12516
J2  - JMIR mHealth uHealth
KW  - mHealth
KW  - systematic review
KW  - cognitive-behavioral therapy
KW  - risk-factors
KW  - adolescent suicide
KW  - metaanalysis
KW  - injury
KW  - diagnosis
KW  - symptoms
KW  - thoughts
KW  - ideation
KW  - validity
KW  - Health Care Sciences &amp; Services
KW  - Medical Informatics
L1  - internal-pdf://2975508372/Melia.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: KD5PXTimes Cited: 0Cited Reference Count: 61Melia, Ruth Francis, Kady Hickey, Emma Bogue, John Duggan, Jim O&#039;Sullivan, Mary Young, KarenDuggan, Jim/0000-0002-7507-8617; Melia, Ruth/0000-0002-1152-5510; Young, Karen/0000-0002-9452-2293; Bogue, John/0000-0002-7070-1561; O&#039;Sullivan, Mary/0000-0003-0832-692106Jmir publications, incToronto
PY  - 2020
SP  - 14
T2  - Jmir Mhealth and Uhealth
TI  - Mobile Health Technology Interventions for Suicide Prevention: Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000507919000001
VL  - 8
ER  -
TY  - JOUR
AB  - Bakgrunn
Olweus programmet (Olweus Bully Prevention Program; OBPP) skal redusere mobbing og antisosial atferd i skolen gjennom å skape et trygt og godt læringsmiljø for alle. Denne artikkelen er en kunnskapsoppsummering om effekter av det forebyggende og skoleomfattende OBPP mot mobbing og antisosial atferd i grunnskolen, en vurdering av om tiltaket er virksomt og anbefalt til bruk i norske skoler.

Metode
Kunnskapsoppsummeringen bygger på systematiske litteratursøk i ulike databaser som Embase, Medline, Psykinfo, Norart, Cochrane, Cristin, Nora, Scopus, Campbell og Blueprint. I tillegg er informasjon innhentet fra tiltakseier.

Resultater
Det ble identifisert seks norske effektstudier, tre egne effektstudier fra USA og to uavhengige studier fra USA, to internasjonale meta-analyser og en internasjonal vurdering (Blueprint, som viser at OPBB oppfyller kravene til såkalt Blueprint- eller modellprogram). Resultatene inkluderer en vurdering av programmets beskrivelse, effektstudier, kvalitet av forskningsmetoder og implementeringskvalitet. Programmet er svært godt beskrevet og har svært gode system for å styrke implementeringskvalitet. Effekten av OBPP er godt beskrevet og dokumentert. Samtidig vil norske effektstudier som i større grad oppfyller dagens krav til dokumentasjon, som omfatter en bredere alderssammensetning og dermed større deler av målgruppen, som er elever i grunnskolen og flere uavhengige studier, styrke dokumentasjonen ytterligere. Resultatene må ses i lys av at utvikling og implementering av OBPP også har etablert et helt nytt fagfelt og forsking innen dette feltet, og representerer et arbeid som strekker seg tilbake til 1970-tallet.

Konklusjon
OBPP klassifiseres etter Ungsinn.no sine kriterier som et dokumentert virksomt tiltak på evidensnivå 5: Tiltak med sterk dokumentasjon på effekt.
AU  - Havik,
AU  - T.,
AU  - Ertresvåg,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2020
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Olweus programmet (OBPP) &ndash; et skoleomfattende program mot mobbing og antisosial atferd (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/olweus-programmet-obpp-2-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - The theoretical background related to how physical activity positively influences children and adolescents&#039; brain function for social and emotional competency has been stably structured. However, according to our review of the literature, no study has synthetically analyzed physical education interventions that produce positive outcomes related to learners&#039; emotional status. Therefore, the aim of the study was to systematically analyze the effectiveness of physical education interventions designed to improve students&#039; emotional ability. In October 2017, we searched electronic research databases for intervention studies that analyzed the impact of school physical education on students&#039; emotional changes. We assessed the risk of bias, extracted data, and conducted meta-analysis to determine the effectiveness of physical education intervention. From an initial pool of 1200 non-duplicate records, 12 studies fulfilled the inclusion criteria. The effectiveness of school-based physical education was analyzed by calculating standard mean difference. Based on the results of the meta-analysis, students in intervention conditions changed their psychological conditions compared with students in usual practice conditions (standardized mean difference=0.30, 95% confidence interval=- 0.05-0.66). Physical and sport education for children and adolescents has positively influenced changes in their emotional conditions.
AD  - Cho, Ooksang. Department of Physical Education, Korea National Sport University, Songpa-gu, Korea (the Republic of).
AN  - 32643773
AU  - Cho,
AU  - O.
DA  - Dec
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1055/a-1192-5812
DP  - Ovid Technologies
J2  - Int J Sports Med
L1  - internal-pdf://2605379231/Cho-2020.pdf
LA  - English
N1  - Cho, Ooksang
PY  - 2020
SP  - 985-993
T2  - International Journal of Sports Medicine
TI  - Impact of Physical Education on Changes in Students&#039; Emotional Competence: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32643773
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32643773&amp;id=doi:10.1055%2Fa-1192-5812&amp;issn=0172-4622&amp;isbn=&amp;volume=41&amp;issue=14&amp;spage=985&amp;pages=985-993&amp;date=2020&amp;title=International+Journal+of+Sports+Medicine&amp;atitle=Impact+of+Physical+Education+on+Changes+in+Students%27+Emotional+Competence%3A+A+Meta-analysis.&amp;aulast=Cho&amp;pid=%3Cauthor%3ECho+O%3C%2Fauthor%3E%3CAN%3E32643773%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1192-5812
UR  - https://www.thieme-connect.com/products/ejournals/pdf/10.1055/a-1192-5812.pdf
VL  - 41
ER  -
TY  - JOUR
AB  - **Objective:** 
The study aimed to evaluate whether resilience-oriented cognitive behavioral interventions (CBIs) which teach cognitive, problem-solving, and social skills are effective for addressing depressive symptoms in the school setting and to investigate factors that could moderate the intervention effects. 

**Method(s):**
 Electronic databases Medline, PsycINFO and Cochrane Central were searched to identify potentially relevant trials. The difference of change from baseline in depressive symptoms between intervention and control condition was assessed. Mean effect sizes (Hedges&#039;g) were calculated using random-effects models. Study-specific characteristics relevant to participant demographics (age, gender, and risk status), intervention conditions (program type, intervention duration, group leader type, and use of homework), and study features (sample size, and methodological quality) were evaluated as potential moderators of the effect size. 

**Result(s):**
38 controlled studies were identified, including 24,135 individuals. At post-intervention, the mean effect size was considered significantly small (Hedges&#039;g = 0.13) and subgroup analyses revealed significant effect sizes for programs administered to both universal and targeted samples, programs both with and without homework, and programs led by school personnel. The mean effect size was largely maintained at 6 months follow-up and subgroup analyses indicated significant effect sizes for programs administered to targeted samples, programs based on Penn Resiliency Program, programs with homework, and programs led by professional interventionists. 

**Conclusion(s):** 
This study reinforces the efficacy of resilience-oriented CBIs for addressing depressive symptoms in the school setting. Although more research is needed to confirm and extend the findings of this study, our findings suggest a range of directions in particular for further investigation. Copyright &copy; 2020 Elsevier B.V.
AD  - (Ma, Zhang) The First Hospital of China Medical University, Shenyang, China (Huang) Department of Sports and Exercise Science, Zhejiang University, Hangzhou, China (Huang) Department of Medicine and Science in Sports and Exercise, Tohoku University Graduate School of Medicine, Sendai, Japan (Cui) School of Pharmacy, China Medical University, Shenyang, ChinaL. Ma, The First Hospital of China Medical University, Shenyang, China. E-mail: louis.liang.ma@hotmail.com
AN  - 2005575773
AU  - Ma,
AU  - L.
AU  - Zhang,
AU  - Y.
AU  - Huang,
AU  - C.
AU  - Cui,
AU  - Z.
DA  - 1 June
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2020.03.051
DP  - Ovid Technologies
KW  - Cognitive behavioral
KW  - Controlled trial
KW  - Depressive symptoms
KW  - Meta-analysis
KW  - Resilience
KW  - adolescent
KW  - child
KW  - Cochrane Library
KW  - demography
KW  - depression
KW  - effect size
KW  - female
KW  - follow up
KW  - gender
KW  - human
KW  - leadership
KW  - male
KW  - Medline
KW  - problem solving
KW  - PsycINFO
KW  - review
KW  - sample size
KW  - social competence
KW  - systematic review
L1  - internal-pdf://2005646977/Ma-2020-Resilience-oriented cognitive behavior.pdf
LA  - English
M3  - Review
PY  - 2020
SP  - 150-164
T2  - Journal of Affective Disorders
TI  - Resilience-oriented cognitive behavioral interventions for depressive symptoms in children and adolescents: A meta-analytic review
UR  - http://www.elsevier.com/locate/jad
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2005575773
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jad.2020.03.051&amp;issn=0165-0327&amp;isbn=&amp;volume=270&amp;issue=&amp;spage=150&amp;pages=150-164&amp;date=2020&amp;title=Journal+of+Affective+Disorders&amp;atitle=Resilience-oriented+cognitive+behavioral+interventions+for+depressive+symptoms+in+children+and+adolescents%3A+A+meta-analytic+review&amp;aulast=Ma&amp;pid=%3Cauthor%3EMa+L.%3C%2Fauthor%3E%3CAN%3E2005575773%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0165032719300436?via%3Dihub
UR  - https://pdf.sciencedirectassets.com/271035/1-s2.0-S0165032720X00073/1-s2.0-S0165032719300436/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEJb%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQCx2USzkywuLtk6W3ntDrzE3TlHDyYWVKxWedQPpUWsDgIhANzS9ZEf8baQUbjOTzgelnnSJCPuOuaplgdyOYLXw9TEKr0DCM7%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEQAxoMMDU5MDAzNTQ2ODY1Igw3wYdwJ%2B15xXpLq7gqkQOm4bqmGBDm4cupz01FTCaLD%2Fy0nHB4JbcmMGmZ6Eme8KkhyM7i28124Osr285%2F2AVp2MTj6ZiCkQTbXMePF0MM%2BArsiAvYc2fLdCO8Ui2Vckiug8bglqEs7RiSvAyiBistmJpcn04%2F%2F94tZH%2FchjLDQ%2BRvM1X%2F3Wtdrq1ldzt86fO7wnS%2FQpIey0G3iWaYf5TQVDt7WqSyTue%2FB4cKjJXO9drhtZjHmFdevc3srFX0ELlZl23ByiLKl4GK7FVNjEFB%2FyAnntvpxJ1WRGX8Saj2IPu6%2BP5O%2F91Ugdnw6zwqMbhBRNo6NQn52VccspKL2tAMS%2FcnVMLkzjR0%2B3kMleNN6VW7Hv%2FSt4PlyM439NyM%2BZgeRIur7ty7eOtaBDQdFa%2FN4JOErYedqmNVNbf0q9vIOIrGGyl0b9vMLniIR0dDnv8858fnoL4xEG9eR3I2GxEcHCmw8mTIRQaZm8HzQWI9esyJ5CbpZzZFvzvD7Mdf4wUq1pSTtriuNEAq450rs%2BfIADxgmCAiAkiKybfT9AIaizC%2B0dP1BTrqAUrUz2%2BeBjGbRkyTaAvhiq7oueMWpZG7rW8HlPi6E%2BWl6%2BbiEDZyevaMdQRCilhU2gl7MSRE9HHB0Zp70NekyxIkSQbe%2Fv4c1yR86XQPidTIoSazfaYtObyEV4c2sju2iIp%2BaTg1swp9v1DQfzq42YFYDi1XgZUTA2mmB%2BL38adVkfPtCmJJCBnau9TpB1kodeiI9LZy1FHHz1ulHlWfkQ8tU6TzeT9zf5RHU9PWG0yA2jtvWYnZvMww8u96euvqTnpbvqC4tN1TmV6tSrlGz2%2FeNmDFoNtFKH%2FH5irdwC8sbQTa36bp8DSD7A%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200508T060128Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY6RZ6PKWK%2F20200508%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=cab71323f1f20b7c2763859251d7fd5241c7f9c79fb4f4ebed7c1eb7464ad183&amp;hash=2f3d8806983807d2487fee8011e4971dd3fc1096f48d454aba5c788f3d665235&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0165032719300436&amp;tid=spdf-afc60ddc-46c6-4b0f-8301-ba4409e70f9d&amp;sid=b928b59760ca894f0a6a8817de603f33c23bgxrqb&amp;type=client
VL  - 270
ER  -
TY  - JOUR
AB  - **Background**
Over the decades, a variety of psychological interventions for borderline personality disorder (BPD) have been developed. This review updates and replaces an earlier review (Stoffers‐Winterling 2012).

**Objectives**
To assess the beneficial and harmful effects of psychological therapies for people with BPD.

**Search methods**
In March 2019, we searched CENTRAL, MEDLINE, Embase, 14 other databases and four trials registers. We contacted researchers working in the field to ask for additional data from published and unpublished trials, and handsearched relevant journals. We did not restrict the search by year of publication, language or type of publication.

**Selection criteria**
Randomised controlled trials comparing different psychotherapeutic interventions with treatment‐as‐usual (TAU; which included various kinds of psychotherapy), waiting list, no treatment or active treatments in samples of all ages, in any setting, with a formal diagnosis of BPD. The primary outcomes were BPD symptom severity, self‐harm, suicide‐related outcomes, and psychosocial functioning. There were 11 secondary outcomes, including individual BPD symptoms, as well as attrition and adverse effects.

**Data collection and analysis**
At least two review authors independently selected trials, extracted data, assessed risk of bias using Cochrane&#039;s &#039;Risk of bias&#039; tool and assessed the certainty of the evidence using the GRADE approach. We performed data analysis using Review Manager 5 and quantified the statistical reliability of the data using Trial Sequential Analysis.

**Main results**
We included 75 randomised controlled trials (4507 participants), predominantly involving females with mean ages ranging from 14.8 to 45.7 years. More than 16 different kinds of psychotherapy were included, mostly dialectical behaviour therapy (DBT) and mentalisation‐based treatment (MBT). The comparator interventions included treatment‐as‐usual (TAU), waiting list, and other active treatments. Treatment duration ranged from one to 36 months.

Psychotherapy versus TAU

Psychotherapy reduced BPD symptom severity, compared to TAU; standardised mean difference (SMD) &minus;0.52, 95% confidence interval (CI) &minus;0.70 to &minus;0.33; 22 trials, 1244 participants; moderate‐quality evidence. This corresponds to a mean difference (MD) of &minus;3.6 (95% CI &minus;4.4 to &minus;2.08) on the Zanarini Rating Scale for BPD (range 0 to 36), a clinically relevant reduction in BPD symptom severity (minimal clinical relevant difference (MIREDIF) on this scale is &minus;3.0 points).

Psychotherapy may be more effective at reducing self‐harm compared to TAU (SMD &minus;0.32, 95% CI &minus;0.49 to &minus;0.14; 13 trials, 616 participants; low‐quality evidence), corresponding to a MD of &minus;0.82 (95% CI &minus;1.25 to 0.35) on the Deliberate Self‐Harm Inventory Scale (range 0 to 34). The MIREDIF of &minus;1.25 points was not reached.

Suicide‐related outcomes improved compared to TAU (SMD &minus;0.34, 95% CI &minus;0.57 to &minus;0.11; 13 trials, 666 participants; low‐quality evidence), corresponding to a MD of &minus;0.11 (95% CI &minus;0.19 to &minus;0.034) on the Suicidal Attempt Self Injury Interview. The MIREDIF of &minus;0.17 points was not reached.

Compared to TAU, psychotherapy may result in an improvement in psychosocial functioning (SMD &minus;0.45, 95% CI &minus;0.68 to &minus;0.22; 22 trials, 1314 participants; low‐quality evidence), corresponding to a MD of &minus;2.8 (95% CI &minus;4.25 to &minus;1.38), on the Global Assessment of Functioning Scale (range 0 to 100). The MIREDIF of &minus;4.0 points was not reached.

Our additional Trial Sequential Analysis on all primary outcomes reaching significance found that the required information size was reached in all cases.

A subgroup analysis comparing the different types of psychotherapy compared to TAU showed no clear evidence of a difference for BPD severity and psychosocial functioning.

Psychotherapy may reduce depressive symptoms compared to TAU but the evidence is very uncertain (SMD &minus;0.39, 95% CI &minus;0.61 to &minus;0.17; 22 trials, 1568 participants; very low‐quality evidence), corresponding to a MD of &minus;2.45 points on the Hamilton Depression Scale (range 0 to 50). The MIREDIF of &minus;3.0 points was not reached.

BPD‐specific psychotherapy did not reduce attrition compared with TAU. Adverse effects were unclear due to too few data.

Psychotherapy versus waiting list or no treatment

Greater improvements in BPD symptom severity (SMD &minus;0.49, 95% CI &minus;0.93 to &minus;0.05; 3 trials, 161 participants), psychosocial functioning (SMD &minus;0.56, 95% CI &minus;1.01 to &minus;0.11; 5 trials, 219 participants), and depression (SMD &minus;1.28, 95% CI &minus;2.21 to &minus;0.34, 6 trials, 239 participants) were observed in participants receiving psychotherapy versus waiting list or no treatment (all low‐quality evidence). No evidence of a difference was found for self‐harm and suicide‐related outcomes.

Individual treatment approaches

DBT and MBT have the highest numbers of primary trials, with DBT as subject of one‐third of all included trials, followed by MBT with seven RCTs.

Compared to TAU, DBT was more effective at reducing BPD severity (SMD &minus;0.60, 95% CI &minus;1.05 to &minus;0.14; 3 trials, 149 participants), self‐harm (SMD &minus;0.28, 95% CI &minus;0.48 to &minus;0.07; 7 trials, 376 participants) and improving psychosocial functioning (SMD &minus;0.36, 95% CI &minus;0.69 to &minus;0.03; 6 trials, 225 participants). MBT appears to be more effective than TAU at reducing self‐harm (RR 0.62, 95% CI 0.49 to 0.80; 3 trials, 252 participants), suicidality (RR 0.10, 95% CI 0.04, 0.30, 3 trials, 218 participants) and depression (SMD &minus;0.58, 95% CI &minus;1.22 to 0.05, 4 trials, 333 participants). All findings are based on low‐quality evidence. For secondary outcomes see review text.

**Authors&#039; conclusions**
Our assessments showed beneficial effects on all primary outcomes in favour of BPD‐tailored psychotherapy compared with TAU. However, only the outcome of BPD severity reached the MIREDIF‐defined cut‐off for a clinically meaningful improvement. Subgroup analyses found no evidence of a difference in effect estimates between the different types of therapies (compared to TAU) .

The pooled analysis of psychotherapy versus waiting list or no treatment found significant improvement on BPD severity, psychosocial functioning and depression at end of treatment, but these findings were based on low‐quality evidence, and the true magnitude of these effects is uncertain. No clear evidence of difference was found for self‐harm and suicide‐related outcomes.

However, compared to TAU, we observed effects in favour of DBT for BPD severity, self‐harm and psychosocial functioning and, for MBT, on self‐harm and suicidality at end of treatment, but these were all based on low‐quality evidence. Therefore, we are unsure whether these effects would alter with the addition of more data.
AN  - CD012955
AU  - Storebø,
AU  - O.
AU  - J.
AU  - Stoffers-Winterling,
AU  - J.
AU  - M.
AU  - V&ouml;llm,
AU  - B.
AU  - A.
AU  - Kongerslev,
AU  - M.
AU  - T.
AU  - Mattivi,
AU  - J.
AU  - T.
AU  - Jørgensen,
AU  - M.
AU  - S.
AU  - Faltinsen,
AU  - E.
AU  - Todorovac,
AU  - A.
AU  - Sales,
AU  - C.
AU  - P.
AU  - Callesen,
AU  - H.
AU  - E.
AU  - et
AU  - al.,
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD012955.pub2
KW  - Adolescent
KW  - Adult
KW  - Borderline Personality Disorder [*therapy]
KW  - Depression [therapy]
KW  - Dialectical Behavior Therapy [statistics &amp; numerical data]
KW  - Female
KW  - Humans
KW  - Male
KW  - Mentalization
KW  - Middle Aged
KW  - Patient Dropouts [statistics &amp; numerical data]
KW  - Psychotherapy [*methods, statistics &amp; numerical data]
KW  - Randomized Controlled Trials as Topic
KW  - Self-Injurious Behavior [therapy]
KW  - Suicide Prevention
KW  - Treatment Outcome
KW  - Waiting Lists
KW  - Young Adult
L1  - internal-pdf://1561609521/Storeb-_sup_a__sup__et_al-2020-Cochrane_Databa.pdf
N1  - [Developmental, Psychosocial and Learning Problems]
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological therapies for people with borderline personality disorder
UR  - https://doi.org//10.1002/14651858.CD012955.pub2
ER  -
TY  - JOUR
AB  - **Background:** 
Depression is a prevalent and disabling condition in youth. Treatment efficacy has been demonstrated for several therapeutic modalities. Acceptability of treatments is also important to explore and was addressed by investigating treatment dropout using meta-analyses. 

**Method(s):** 
A systematic search was conducted using MEDLINE, CINAHL and PsycARTICLES databases. Peer-reviewed randomised controlled trials investigating psychotherapy treatment of depression in children and youth (aged up to and including 18 years) were included. Proportion meta-analyses were used to calculate estimated dropout rates; odds ratios assessed whether there was greater dropout from intervention or control arms and meta-regressions investigated for associations between dropout, study and treatment characteristics. 

**Result(s):** 
Thirty-seven studies were included (N=4343). Overall estimate of dropout from active interventions was 14.6% (95% CI 12.0-17.4%). Dropout was equally likely from intervention and control conditions, aside from family/dyadic interventions (where dropout was more likely from control arms). There was some suggestion that interventions offering more sessions and longer duration had less dropout and of less dropout from IPT than other interventions. There were no significant associations between dropout and study quality, CBT, family or individual versus other approaches. Limitation(s): Lack of consistent reporting decreased the factors which could be analysed. 

**Conclusion(s):** 
Dropout from depression treatment in children and youth was similar across different types of intervention and control conditions. Future treatment trials should specify minimum treatment dose, define dropout and provide information about participants who dropout. This may inform treatment choice and modification of treatments. Copyright &copy; 2020
AD  - (Wright, Bowers, Meiser-Stedman) Department of Clinical Psychology, University of East Anglia, Norwich, United Kingdom (Wright, Mughal) Cambridgeshire and Peterborough NHS Foundation TrustR. Meiser-Stedman, Department of Clinical Psychology, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, United Kingdom. E-mail: r.meiser-stedman@uea.ac.uk
AN  - 2010117986
AU  - Wright,
AU  - I.
AU  - Mughal,
AU  - F.
AU  - Bowers,
AU  - G.
AU  - Meiser-Stedman,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.jad.2020.11.039
DP  - Ovid Technologies
KW  - depression
KW  - dropout
KW  - meta-analysis
KW  - psychotherapy
KW  - youth
KW  - child
KW  - Cinahl
KW  - female
KW  - human
KW  - juvenile
KW  - male
KW  - Medline
KW  - meta analysis
KW  - patient dropout
KW  - randomized controlled trial (topic)
KW  - review
KW  - systematic review
L1  - internal-pdf://2308441334/Wright-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - Journal of Affective Disorders.
TI  - Dropout from randomised controlled trials of psychological treatments for depression in children and youth: a systematic review and meta-analyses
UR  - http://www.elsevier.com/locate/jad
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2010117986
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:33248810&amp;id=doi:10.1016%2Fj.jad.2020.11.039&amp;issn=0165-0327&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Journal+of+Affective+Disorders&amp;atitle=Dropout+from+randomised+controlled+trials+of+psychological+treatments+for+depression+in+children+and+youth%3A+a+systematic+review+and+meta-analyses&amp;aulast=Wright&amp;pid=%3Cauthor%3EWright+I.%3C%2Fauthor%3E%3CAN%3E2010117986%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0165032720329694?via%3Dihub
ER  -
TY  - JOUR
AB  - Empirical evidence suggests inattention and attention-deficit/hyperactivity disorder (ADHD) are related to reading fluency, reading comprehension, and academic failure. Students with ADHD are served in both general and special education settings, but limited research explores effective reading interventions for this population. The purpose of this synthesis is to investigate reading studies for participants identified with or at risk of ADHD. We address the following research question: What are the effects of reading interventions on the reading outcomes of students with or at risk of ADHD in Grades 4 to 12? In total, 16 studies met inclusion criteria. Intervention findings are presented in an attempt to document evidence-based practices. Although findings contribute to the evidence base of instructional practices that may be effective for students with ADHD, no interventions meet criteria outlined by the Council for Exceptional Children to be classified as evidence-based practices. However, studies in this review document evidence of positive intervention effects for study participants.
AN  - WOS:000584539600003
AU  - Stewart,
AU  - A.
AU  - A.
AU  - Austin,
AU  - C.
AU  - R.
DA  - Dec
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/0741932519849660
L1  - internal-pdf://0266505923/Stewart-2020.pdf
N1  - Stewart, Alicia A. Austin, Christy R.1538-4756
PY  - 2020
SP  - 352-367
T2  - Remedial and Special Education
TI  - Reading Interventions for Students With or At Risk of Attention-Deficit/Hyperactivity Disorder: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000584539600003
UR  - https://journals.sagepub.com/doi/10.1177/0741932519849660
UR  - https://journals.sagepub.com/doi/pdf/10.1177/0741932519849660
VL  - 41
ER  -
TY  - JOUR
AB  - As many as one third of children who reunify from child welfare systems reenter care because of continued child maltreatment. This can have long-term deleterious effects on mental health. Yet, few studies have examined interventions that have been effective in promoting successful reunification or reunification that does not result in recidivism. This study presents findings from a systematic review of interventions that target successful reunification. We searched five academic databases, governmental and educational websites to identify prior literature. Three researchers extracted data from N= 216 studies retrieved and screened in 10 that met all inclusion criteria. However, small sample sizes, lack of replication of studies, and small effect sizes limit the generalizability of findings. As such, the findings from this review highlight a need for more rigorous studies to build the evidence base of post-permanence interventions for families that reunify.
AN  - WOS:000543442600001
AU  - LaBrenz,
AU  - C.
AU  - A.
AU  - Panisch,
AU  - L.
AU  - S.
AU  - Liu,
AU  - C.
AU  - Fong,
AU  - R.
AU  - Franklin,
AU  - C.
DA  - Nov
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/1049731520936747
L1  - internal-pdf://3962138686/LaBrenz-2020.pdf
N1  - LaBrenz, Catherine A. Panisch, Lisa S. Liu, Chun Fong, Rowena Franklin, Cynthia1552-7581
PY  - 2020
SP  - 832-845
T2  - Research on Social Work Practice
TI  - Reunifying Successfully: A Systematic Review of Interventions to Reduce Child Welfare Recidivism
UR  - &lt;Go to ISI&gt;://WOS:000543442600001
UR  - https://journals.sagepub.com/doi/10.1177/1049731520936747
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1049731520936747
VL  - 30
ER  -
TY  - JOUR
AB  - The number of secondary-level students with high-functioning autism (HFA) served in public school settings has increased in recent years, and many of these students have difficulty with social-behavioral expectations in such settings. Instructional specialists must know which interventions have been shown to be effective, so they can make informed decisions about service delivery and instructional support (professional development) that maximize the potential for student success. The intent of the present meta-analysis was to examine the efficacy of social-behavioral interventions used with adolescent students with HFA served in public school settings. Thirteen studies employing single-case research designs published in peer-reviewed journals between 1987 and 2018 were found through an extensive literature search. The analyses indicated that specific social skill and behavioral interventions had high effect sizes and, likewise, improved outcomes for students with HFA. Implications for special education practice and future research are provided. Copyright &copy; Hammill Institute on Disabilities 2019.
AD  - (McKeithan) The University of Kansas, Lawrence, United States (Sabornie) North Carolina State University, Raleigh, United StatesG.K. McKeithan, The University of Kansas, Lawrence, United States. E-mail: gmckeithan@ku.edu
AN  - 2003736110
AU  - McKeithan,
AU  - G.
AU  - K.
AU  - Sabornie,
AU  - E.
AU  - J.
DA  - 01 Sep
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1088357619890312
DP  - Ovid Technologies
KW  - adolescents
KW  - Asperger syndrome
KW  - autism
KW  - autism spectrum disorder
KW  - behavioral interventions
KW  - high-functioning autism
KW  - interventions
KW  - meta-analysis
KW  - public school settings
KW  - social skill interventions
KW  - social-behavioral interventions
KW  - adolescent
KW  - effect size
KW  - female
KW  - health care delivery
KW  - human
KW  - letter
KW  - male
KW  - meta analysis
KW  - social competence
KW  - special education
L1  - internal-pdf://3636934582/McKeithan-2020-Social-Behavioral Interventions.pdf
LA  - English
PY  - 2020
SP  - 165-175
T2  - Focus on Autism and Other Developmental Disabilities
TI  - Social-Behavioral Interventions for Secondary-Level Students With High-Functioning Autism in Public School Settings: A Meta-Analysis
UR  - http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201875
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2003736110
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1177%2F1088357619890312&amp;issn=1088-3576&amp;isbn=&amp;volume=35&amp;issue=3&amp;spage=165&amp;pages=165-175&amp;date=2020&amp;title=Focus+on+Autism+and+Other+Developmental+Disabilities&amp;atitle=Social-Behavioral+Interventions+for+Secondary-Level+Students+With+High-Functioning+Autism+in+Public+School+Settings%3A+A+Meta-Analysis&amp;aulast=McKeithan&amp;pid=%3Cauthor%3EMcKeithan+G.K.%3C%2Fauthor%3E%3CAN%3E2003736110%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1088357619890312
VL  - 35
ER  -
TY  - JOUR
AB  - Depression and anxiety pose a significant burden during adolescence, which may have consequences for adulthood and future generations. The mental health needs of children and adolescents in low- and middle-income countries are not adequately addressed due to a lack of availability and access to services, and limited intervention research in these contexts. Universal school-based interventions provide a unique and potentially scalable opportunity to prevent and address mental health concerns amongst children and adolescents in low- and middle-income countries. This systematic review aimed to identify and provide a narrative synthesis of universal school-based programmes delivered to children (aged 6-18years) in low- and middle-income countries reporting on anxiety and/or depression outcomes. We searched Academic Search Premier, ERIC, PsycINFO, PubMed, Scopus, Web of Science, and ProQuest Dissertations using a pre-specified search strategy. Of the 12,478 articles identified, 12 studies met our inclusion criteria and were included in this review. The studies included report on a variety of interventions differing in approach, format and content. Given the small number of studies and concerns with study quality, we are unable to conclude that universal school-based interventions may reduce symptoms of anxiety and depression in children in low- and middle-income countries.
AD  - Bradshaw, Melissa. Department of Psychology, Stellenbosch University,Private Bag X1, Matieland, Stellenbosch 7602, South Africa. Electronic address: melissab@sun.ac.za.Gericke, Hermine. Department of Psychology, Stellenbosch University,Private Bag X1, Matieland, Stellenbosch 7602, South Africa. Electronic address: hmkruger@sun.ac.za.Coetzee, Bronwyne J. Department of Psychology, Stellenbosch University,Private Bag X1, Matieland, Stellenbosch 7602, South Africa. Electronic address: bronwyne@sun.ac.za.Stallard, Paul. Department for Health, 1 West, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom. Electronic address: ps238@bath.ac.uk.Human, Suzanne. Department of Psychology, Stellenbosch University,Private Bag X1, Matieland, Stellenbosch 7602, South Africa. Electronic address: shuman@sun.ac.za.Loades, Maria. Department of Psychology, 10 West, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom. Electronic address: mel26@bath.ac.uk.
AN  - 33159922
AU  - Bradshaw,
AU  - M.
AU  - Gericke,
AU  - H.
AU  - Coetzee,
AU  - B.
AU  - J.
AU  - Stallard,
AU  - P.
AU  - Human,
AU  - S.
AU  - Loades,
AU  - M.
DA  - Nov 04
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ypmed.2020.106317
DP  - Ovid Technologies
J2  - Prev Med
L1  - internal-pdf://2455061002/Bradshaw-2020.pdf
LA  - English
M3  - Review
N1  - Bradshaw, MelissaGericke, HermineCoetzee, Bronwyne JStallard, PaulHuman, SuzanneLoades, MariaS0091-7435(20)30341-8
PY  - 2020
SP  - 106317
T2  - Preventive Medicine
TI  - Universal school-based mental health programmes in low- and middle-income countries: A systematic review and narrative synthesis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=33159922
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:33159922&amp;id=doi:10.1016%2Fj.ypmed.2020.106317&amp;issn=0091-7435&amp;isbn=&amp;volume=&amp;issue=&amp;spage=106317&amp;pages=106317&amp;date=2020&amp;title=Preventive+Medicine&amp;atitle=Universal+school-based+mental+health+programmes+in+low-+and+middle-income+countries%3A+A+systematic+review+and+narrative+synthesis.&amp;aulast=Bradshaw&amp;pid=%3Cauthor%3EBradshaw+M%3C%2Fauthor%3E%3CAN%3E33159922%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Background:** 
Tic disorders (TDs) are chronic neuropsychiatric disorders that usually begin in childhood. Currently, antipsychotic drugs, such as aripiprazole and risperidone, are frequently used to treat TD. However, adverse reactions limit their further usage. The efficacy of topiramate has been reported in recent studies. This study aimed to investigate the efficacy and tolerability of topiramate in the treatment of children with TDs. 

**Methods:** 
In this study, we performed a meta-analysis to assess the efficacy and tolerability of topiramate for TDs and identified the randomized controlled trials to evaluate topiramate for children with TDs from PubMed, the China National Knowledge Infrastructure database, Web of Science, and relevant reference lists. Quality assessment followed the Cochrane Handbook for Systematic Reviews of Interventions. A modified Jadad scale was used to assess the quality of included studies. Risk ratio (RR) was calculated as the effect size of efficacy and tolerability of topiramate for TDs. 

**Results:**
A total of 15 studies involving 1070 participants aged 2-17 were included in the present meta-analysis, and 693 (64.71%) participants were male cases, with 14 studies evaluating the efficacy of topiramate for the treatment of TD. The results suggested that topiramate was more effective than control drugs (RR: 1.13, 95% confidence interval: [1.06-1.20], I2 = 36%, Q = 20.31, p = 0.09). For the adverse events, there were 15 trials included in the meta-analysis, and the results showed that topiramate had fewer adverse events than control drugs (RR: 0.54, 95% confidence interval: [0.46-0.65], I2 = 45%, Q = 25.49, p = 0.03). 

**Conclusion:** 
Compared with haloperidol and tiapride, topiramate appears to be a promising medication with good efficacy and tolerability for children with TDs. In future studies, large-sample, double-blind, placebo-controlled trials are needed to confirm its efficacy and tolerability compared with atypical antipsychotic agents (such as risperidone or aripiprazole). (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - Cui, Yonghua: cuiyonghuapsy@126.com; Li, Ying: cuiyonghuapsy@126.comCui, Yonghua: Department of Psychiatry, National Center for Children&#039;s Health, Beijing Children&#039;s Hospital, Capital Medical University, Nanlishi Road 56, Beijing, China, 100045, cuiyonghuapsy@126.comYu, Liping: Department of Psychiatry, Beijing Children&#039;s Hospital, Capital Medical University, National Center for Children&#039;s Health, Beijing, ChinaYan, Junjuan: Department of Psychiatry, Beijing Children&#039;s Hospital, Capital Medical University, National Center for Children&#039;s Health, Beijing, ChinaWen, Fang: Department of Psychiatry, Beijing Children&#039;s Hospital, Capital Medical University, National Center for Children&#039;s Health, Beijing, ChinaWang, Fang: Department of Psychiatry, Beijing Children&#039;s Hospital, Capital Medical University, National Center for Children&#039;s Health, Beijing, ChinaLiu, Jingran: Department of Psychiatry, Beijing Children&#039;s Hospital, Capital Medical University, National Center for Children&#039;s Health, Beijing, ChinaCui, Yonghua: Department of Psychiatry, Beijing Children&#039;s Hospital, Capital Medical University, National Center for Children&#039;s Health, Beijing, ChinaLi, Ying: Department of Psychiatry, Beijing Children&#039;s Hospital, Capital Medical University, National Center for Children&#039;s Health, Beijing, China
AN  - 2020-20757-001
AU  - Yu,
AU  - Liping
AU  - Yan,
AU  - Junjuan
AU  - Wen,
AU  - Fang
AU  - Wang,
AU  - Fang
AU  - Liu,
AU  - Jingran
AU  - Cui,
AU  - Yonghua
AU  - Li,
AU  - Ying
DA  - Sept 21
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1089/cap.2019.0161
DP  - Ovid Technologies
KW  - topiramate, tic disorders, Tourette syndrome, children
KW  - *Anticonvulsive Drugs
KW  - *Drug Therapy
KW  - *Drug Tolerance
KW  - *Risperidone
KW  - *Tics
KW  - Neuroleptic Drugs
KW  - Treatment Effectiveness Evaluation
KW  - Aripiprazole
KW  - Clinical Psychopharmacology [3340]
KW  - Human
L1  - internal-pdf://3515570848/Yu-2020-Revisiting the efficacy and tolerabili.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
SP  - 316-325
T2  - Journal of Child and Adolescent Psychopharmacology
TI  - Revisiting the efficacy and tolerability of topiramate for tic disorders: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2020-20757-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1089%2Fcap.2019.0161&amp;issn=1044-5463&amp;isbn=&amp;volume=30&amp;issue=5&amp;spage=316&amp;pages=316-325&amp;date=2020&amp;title=Journal+of+Child+and+Adolescent+Psychopharmacology&amp;atitle=Revisiting+the+efficacy+and+tolerability+of+topiramate+for+tic+disorders%3A+A+meta-analysis.&amp;aulast=Yu&amp;pid=%3Cauthor%3EYu%2C+Liping%3C%2Fauthor%3E%3CAN%3E2020-20757-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.liebertpub.com/doi/pdfplus/10.1089/cap.2019.0161
VL  - 30
ER  -
TY  - JOUR
AB  - **Background**
Road traffic suicides are common. However, due to the difficulty in distinguishing between motor vehicle crash fatalities and actual suicides, no official figures exist for this method of suicide. Restricting access to means is an important universal or population‐based approach to suicide prevention with clear evidence of its effectiveness. However, the evidence with respect to means restriction for the prevention of suicide on roads is not well established. We conducted a systematic review to assess the impact of restrictions on the availability of, or access to, means of suicide on roads.

**Objectives**
To evaluate the effectiveness of interventions to restrict the availability of, or access to, means of suicide on roads.

**Search methods**
We searched the Cochrane Library, MEDLINE, Embase, PsycINFO, and the Transport Research International Documentation (TRID) Database from the date of database inception to March 2020. We conducted searches of the World Health Organization International Clinical Trials Registry Platform (ICTRP) and ClinicalTrials.gov to identify unpublished and ongoing studies. We applied no date, language, or publication status restrictions to these searches.

**Selection criteria**
Eligible studies were randomised or quasi‐randomised controlled trials, controlled intervention studies without randomisation, before‐after studies, or studies using interrupted time series designs, which evaluated interventions to restrict the availability of, or access to, means of suicide on roads.

**Data collection and analysis**
Two review authors screened abstracts and full‐text publications against the inclusion criteria. Two review authors planned to independently extract data and assess risk of bias of included studies. However, we identified no studies eligible for inclusion.

**Main results**
We identified no studies that met the inclusion criteria for this review.

**Authors&#039; conclusions**
This systematic review highlights the paucity of research around road traffic suicides and the need for future robust studies that aim to investigate the effectiveness of interventions to prevent suicide on roads. Suicide ascertainment is a key issue; therefore, clear objective criteria are necessary in order to scale up and study this method more accurately. In the absence of any substantial evidence, we advocate for more awareness on road traffic suicides and its inclusion in future government suicide prevention policies. Further research exploring effective measures, particularly those that do not require driver compliance, are also needed.
AU  - Okolie,
AU  - C.
AU  - Hawton,
AU  - K.
AU  - Lloyd,
AU  - K.
AU  - Price,
AU  - S.
AU  - F.
AU  - Dennis,
AU  - M.
AU  - John,
AU  - A.
DA  - September
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013738
L1  - internal-pdf://1996166934/Okolie_et_al-2020-Cochrane_Database_of_Systema.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Means restriction for the prevention of suicide on roads
ER  -
TY  - JOUR
AB  - This paper presents the results from a meta-analytical review of the effectiveness of bullying prevention programs for boys and girls. A systematic search of three online databases was conducted of evaluations published between 1990 and 2018. The abstract review returned 352 articles, after full-text review the search yielded a final sample of 22 articles. The overall whole sample results suggest that bullying prevention programs are effective at reducing bullying among boys, but not girls; however, further analysis revealed that the programs are effective for both boys and girls outside of the United States, and ineffective for both boys and girls within the United States. Overall (both within and outside the United States), boys who participated in a bullying prevention program had 15% (95% CI: 1.01-1.31, p &lt; .05) higher odds of a reduction in bullying victimization compared to boys in the control group, while boys and girls outside of the United States had 34% (95% CI: 1.11-1.62, p &lt; .01) and 21% (95% CI: 1.00-1.62, p &lt; .05) higher odds of a reduction bullying victimization. The findings suggest that prevention programs are largely effective at reducing bullying victimization, particularly among boys, but might be less effective among girls overall, and for both boys and girls within the United States. Future research needs to explore the impact of prevention programs on girls, as well as the divergent effect of programs within the United States compared to internationally. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - Kennedy, Reeve S.: rxk5442@psu.eduKennedy, Reeve S.: Sociology Department, University of New Hampshire, 15 Academic Way, Durham, NH, US, 03824, rxk5442@psu.eduKennedy, Reeve S.: Sociology Department, University of New Hampshire, Durham, NH, US
AN  - 2020-97547-001
AU  - Kennedy,
AU  - Reeve
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.childyouth.2020.105506
DP  - Ovid Technologies
KW  - bullying, peer harassment, victimization, prevention, youth
KW  - *Human Sex Differences
KW  - *Peers
KW  - *Prevention
KW  - *Bullying
KW  - Community &amp; Social Services [3373]
KW  - Human
L1  - internal-pdf://2190844444/Kennedy-2020.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
T2  - Children and Youth Services Review Vol 119 2020, ArtID 105506
TI  - Gender differences in outcomes of bullying prevention programs: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-97547-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2020.105506&amp;issn=0190-7409&amp;isbn=&amp;volume=119&amp;issue=&amp;spage=105506&amp;pages=&amp;date=2020&amp;title=Children+and+Youth+Services+Review&amp;atitle=Gender+differences+in+outcomes+of+bullying+prevention+programs%3A+A+meta-analysis.&amp;aulast=Kennedy&amp;pid=%3Cauthor%3EKennedy%2C+Reeve+S%3C%2Fauthor%3E%3CAN%3E2020-97547-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0190740920308677?via%3Dihub
VL  - 119
ER  -
TY  - JOUR
AB  - The existence of depression among children or adolescents can trigger a sequence of burdens on themselves, their families and even the whole society, which cause both physical and economic impacts. Our network meta-analysis (NMA) was aimed at comparing them with each other for evaluating the optimal psychosocial therapy to help children and adolescents with depression to improve their mental health. Based on several biomedical databases, a system of search strategies was conducted for searching randomized controlled trials (RCTs) which published from their inception on October, 1st 2018 without language restriction. We carried out an expression analysis for comparing the efficacy of various psychosocial therapies using Bayesian NMA. A battery of analyses and assessments, such as conventional meta-analysis and risk of bias, were performed concurrently. Only 32 of RCTs which involved 2677 participants were eventually included in our analyses from the 19,176 of initial citation screening. In addition, in terms of various valid assessment instruments, interpersonal psychotherapy [standard mean difference (SMD) = -1.38, Credible interval (CrI) - 2.5, - 0.20)], computer cognitive-behavioral therapy (SMD = -1.36, CrI - 2.59, - 0.14), cognitive-behavioral therapy (SMD = -1.16, CrI - 2.15, - 0.18), had significantly better effects than the named control group. All together, these results suggest that interpersonal psychotherapy might be the best approach to improve the depressive state among children and adolescents. This study may provide an excellent resource for future endeavors to utilize psychosocial interventions and may also serve as a springboard for creative undertakings as yet unknown.
AD  - Liang, Jing-Hong. Department of Social Medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Liang, Jing-Hong. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, No. 199 Ren Ai Road, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Li, Jing. Department of Social Medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Li, Jing. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, No. 199 Ren Ai Road, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Wu, Rong-Kun. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, No. 199 Ren Ai Road, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Li, Jia-Yu. Department of Social Medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Li, Jia-Yu. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, No. 199 Ren Ai Road, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Qian, Sheng. Department of Social Medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Qian, Sheng. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, No. 199 Ren Ai Road, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Jia, Rui-Xia. Department of Social Medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Wang, Ying-Quan. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, No. 199 Ren Ai Road, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Qian, Yu-Xi. Department of Social Medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, 215123, Jiangsu, People&#039;s Republic of China.Xu, Yong. Department of Social Medicine, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou, 215123, Jiangsu, People&#039;s Republic of China. childhealth@suda.edu.cn.Xu, Yong. Department of Child and Adolescent Health, School of Public Health, Medical College of Soochow University, No. 199 Ren Ai Road, Suzhou, 215123, Jiangsu, People&#039;s Republic of China. childhealth@suda.edu.cn.
AN  - 32076871
AU  - Liang,
AU  - J.
AU  - H.
AU  - Li,
AU  - J.
AU  - Wu,
AU  - R.
AU  - K.
AU  - Li,
AU  - J.
AU  - Y.
AU  - Qian,
AU  - S.
AU  - Jia,
AU  - R.
AU  - X.
AU  - Wang,
AU  - Y.
AU  - Q.
AU  - Qian,
AU  - Y.
AU  - X.
AU  - Xu,
AU  - Y.
DA  - Feb 19
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s00787-020-01492-w
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
L1  - internal-pdf://3892029082/Liang-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingFebLiang, Jing-HongLi, JingWu, Rong-KunLi, Jia-YuQian, ShengJia, Rui-XiaWang, Ying-QuanQian, Yu-XiXu, Yong
PY  - 2020
SP  - 19
T2  - European Child &amp; Adolescent Psychiatry
TI  - Effectiveness comparisons of various psychosocial therapies for children and adolescents with depression: a Bayesian network meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32076871
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32076871&amp;id=doi:10.1007%2Fs00787-020-01492-w&amp;issn=1018-8827&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=Effectiveness+comparisons+of+various+psychosocial+therapies+for+children+and+adolescents+with+depression%3A+a+Bayesian+network+meta-analysis.&amp;aulast=Liang&amp;pid=%3Cauthor%3ELiang+JH%3C%2Fauthor%3E%3CAN%3E32076871%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs00787-020-01492-w
UR  - https://link.springer.com/content/pdf/10.1007/s00787-020-01492-w.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - **Background**
Psychosis is an illness characterised by alterations in thoughts and perceptions resulting in delusions and hallucinations. Psychosis is rare in adolescents but can have serious consequences. Antipsychotic medications are the mainstay treatment, and have been shown to be effective. However, there is emerging evidence on psychological interventions such as cognitive remediation therapy, psycho‐education, family therapy and group psychotherapy that may be useful for adolescents with psychosis.

**Objectives**
To assess the effects of various psychological interventions for adolescents with psychosis.Search methodsWe searched the Cochrane Schizophrenia Group&#039;s study‐based Register of Trials including clinical trials registries (latest, 8 March 2019).

**Selection criteria**
All randomised controlled trials comparing various psychological interventions with treatment‐as‐usual or other psychological treatments for adolescents with psychosis. For analyses, we included trials meeting our inclusion criteria and reporting useable data.

**Data collection and analysis**
We independently and reliably screened studies and we assessed risk of bias of the included studies. For dichotomous data, we calculated risk ratios (RRs) and 95% confidence intervals (CIs) on an intention‐to‐treat basis. For continuous data, we used mean differences (MDs) and the 95% CIs. We used a random‐effects model for analyses. We created a &lsquo;Summary of findings&#039; table using GRADE.

**Main results**
The current review includes 7 studies (n = 319) assessing a heterogenous group of psychological interventions with variable risk of bias. Adverse events were not reported by any of the studies. None of the studies was sponsored by industry. Below, we summarise the main results from four of six comparisons, and the certainty of these results (based on GRADE). All scale scores are average endpoint scores.

Cognitive Remediation Therapy (CRT) + Treatment‐as‐Usual (TAU) versus TAU

Two studies compared adding CRT to participants&#039; TAU with TAU alone. Global state (CGAS, high = good) was reported by one study. There was no clear difference between treatment groups (MD ‐4.90, 95% CI ‐11.05 to 1.25; participants = 50; studies = 1, very low‐certainty). Mental state (PANSS, high = poor) was reported by one study. Scores were clearly lower in the TAU group (MD 8.30, 95% CI 0.46 to 16.14; participants = 50; studies = 1; very low‐certainty). Clearly more participants in the CRT group showed improvement in cognitive functioning (Memory digit span test) compared to numbers showing improvement in the TAU group (1 study, n = 31, RR 0.58, 95% CI 0.37 to 0.89; very low‐certainty). For global functioning (VABS, high = good), our analysis of reported scores showed no clear difference between treatment groups (MD 5.90, 95% CI ‐3.03 to 14.83; participants = 50; studies = 1; very low‐certainty). The number of participants leaving the study early from each group was similar (RR 0.93, 95% CI 0.32 to 2.71; participants = 91; studies = 2; low‐certainty).

Group Psychosocial Therapy (GPT) + TAU versus TAU

One study assessed the effects of adding GPT to participants&#039; usual medication. Global state scores (CGAS, high = good) were clearly higher in the GPT group (MD 5.10, 95% CI 1.35 to 8.85; participants = 56; studies = 1; very low‐certainty) but there was little or no clear difference between groups for mental state scores (PANSS, high = poor, MD ‐4.10, 95% CI ‐8.28 to 0.08; participants = 56; studies = 1, very low‐certainty) and no clear difference between groups for numbers of participants leaving the study early (RR 0.43, 95% CI 0.15 to 1.28; participants = 56; studies = 1; very low‐certainty).

Cognitive Remediation Programme (CRP) + Psychoeducational Treatment Programme (PTP) versus PTP

One study assessed the effects of combining two types psychological interventions (CRP + PTP) with PTP alone. Global state scores (GAS, high = good) were not clearly different (MD 1.60, 95% CI ‐6.48 to 9.68; participants = 25; studies = 1; very low‐certainty), as were mental state scores (BPRS total, high = poor, MD ‐5.40, 95% CI ‐16.42 to 5.62; participants = 24; studies = 1; very low‐certainty), and cognitive functioning scores (SPAN‐12, high = good, MD 2.40, 95% CI ‐2.67 to 7.47; participants = 25; studies = 1; very low‐certainty).

Psychoeducational (PE) + Multifamily Treatment (MFT) Versus Nonstructured Group Therapy (NSGT, all long‐term)One study compared (PE + MFT) with NSGT. Analysis of reported global state scores (CGAS, high = good, MD 3.38, 95% CI ‐4.87 to 11.63; participants = 49; studies = 1; very low‐certainty) and mental state scores (PANSS total, high = poor, MD ‐8.23, 95% CI ‐17.51 to 1.05; participants = 49; studies = 1; very low‐certainty) showed no clear differences. The number of participants needing hospital admission (RR 0.84, 95% CI 0.36 to 1.96; participants = 49; studies = 1) and the number of participants leaving the study early from each group were also similar (RR 0.52, 95% CI 0.10 to 2.60; participants = 55; studies = 1; low‐certainty).

**Authors&#039; conclusions**
Most of our estimates of effect for our main outcomes are equivocal. An effect is suggested for only four outcomes in the SOF tables presented. Compared to TAU, CRT may have a positive effect on cognitive functioning, however the same study reports data suggesting TAU may have positive effect on mental state. Another study comparing GPT with TAU reports data suggesting GPT may have a positive effect on global state. However, the estimate of effects for all the main outcomes in our review should be viewed with considerable caution as they are based on data from a small number of studies with variable risk of bias. Further data could change these results and larger and better quality studies are needed before any firm conclusions regarding the effects of psychological interventions for adolescents with psychosis can be made.
AU  - Datta,
AU  - S,
AU  - S.
AU  - Daruvala,
AU  - R.
AU  - Kumar,
AU  - A.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD009533.pub2
L1  - internal-pdf://1290864463/datta.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological interventions for psychosis in adolescents
ER  -
TY  - JOUR
AB  - **Background**
Human milk as compared to formula reduces morbidity in preterm infants but requires fortification to meet their nutritional needs and to reduce the risk of extrauterine growth failure. Standard fortification methods are not individualized to the infant and assume that breast milk is uniform in nutritional content. Strategies for individualizing fortification are available; however it is not known whether these are safe, or if they improve outcomes in preterm infants.

**Objectives**
To determine whether individualizing fortification of breast milk feeds in response to infant blood urea nitrogen (adjustable fortification) or to breast milk macronutrient content as measured with a milk analyzer (targeted fortification) reduces mortality and morbidity and promotes growth and development compared to standard, non‐individualized fortification for preterm infants receiving human milk at &lt; 37 weeks&#039; gestation or at birth weight &lt; 2500 grams.

**Search methods**
We used the standard search strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2019, Issue 9), in the Cochrane Library; Ovid MEDLINE(R) and Epub Ahead of Print, In‐Process &amp; Other Non‐Indexed Citations, Daily and Versions(R); and the Cumulative Index to Nursing and Allied Health Literature (CINAHL), on September 20, 2019. We also searched clinical trials databases and the reference lists of retrieved articles for pertinent randomized controlled trials (RCTs) and quasi‐randomized trials.

**Selection criteria**
We considered randomized, quasi‐randomized, and cluster‐randomized controlled trials of preterm infants fed exclusively breast milk that compared a standard non‐individualized fortification strategy to individualized fortification using a targeted or adjustable strategy. We considered studies that examined any use of fortification in eligible infants for a minimum duration of two weeks, initiated at any time during enteral feeding, and providing any regimen of human milk feeding.

**Data collection and analysis**
Data were collected using the standard methods of Cochrane Neonatal. Two review authors evaluated the quality of the studies and extracted data. We reported analyses of continuous data using mean differences (MDs), and dichotomous data using risk ratios (RRs). We used the GRADE approach to assess the certainty of evidence.Main resultsData were extracted from seven RCTs, resulting in eight publications (521 total participants were enrolled among these studies), with duration of study interventions ranging from two to seven weeks. As compared to standard non‐individualized fortification, individualized (targeted or adjustable) fortification of enteral feeds probably increased weight gain during the intervention (typical mean difference [MD] 1.88 g/kg/d, 95% confidence interval [CI] 1.26 to 2.50; 6 studies, 345 participants), may have increased length gain during the intervention (typical MD 0.43 mm/d, 95% CI 0.32 to 0.53; 5 studies, 242 participants), and may have increased head circumference gain during the intervention (typical MD 0.14 mm/d, 95% CI 0.06 to 0.23; 5 studies, 242 participants). Compared to standard non‐individualized fortification, targeted fortification probably increased weight gain during the intervention (typical MD 1.87 g/kg/d, 95% CI 1.15 to 2.58; 4 studies, 269 participants) and may have increased length gain during the intervention (typical MD 0.45 mm/d, 95% CI 0.32 to 0.57; 3 studies, 166 participants). Adjustable fortification probably increased weight gain during the intervention (typical MD 2.86 g/kg/d, 95% CI 1.69 to 4.03; 3 studies, 96 participants), probably increased gain in length during the intervention (typical MD 0.54 mm/d, 95% CI 0.38 to 0.7; 3 studies, 96 participants), and increased gain in head circumference during the intervention (typical MD 0.36 mm/d, 95% CI 0.21 to 0.5; 3 studies, 96 participants). We are uncertain whether there are differences between individualized versus standard fortification strategies in the incidence of in‐hospital mortality, bronchopulmonary dysplasia, necrotizing enterocolitis, culture‐proven late‐onset bacterial sepsis, retinopathy of prematurity, osteopenia, length of hospital stay, or post‐hospital discharge growth. No study reported severe neurodevelopmental disability as an outcome. One study that was published after our literature search was completed is awaiting classification.

**Authors&#039; conclusions**
We found moderate‐ to low‐certainty evidence suggesting that individualized (either targeted or adjustable) fortification of enteral feeds in very low birth weight infants increases growth velocity of weight, length, and head circumference during the intervention compared with standard non‐individualized fortification. Evidence showing important in‐hospital and post‐discharge clinical outcomes was sparse and of very low certainty, precluding inferences regarding safety or clinical benefits beyond short‐term growth.
AU  - Fabrizio,
AU  - V.
AU  - Trzaski,
AU  - J.
AU  - Brownell,
AU  - E.
AU  - Esposito,
AU  - P.
AU  - Lainwala,
AU  - S.
AU  - Lussier.
AU  - M.
AU  - Hagadorn,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/14651858.CD013465.pub2
L1  - internal-pdf://4218472981/Fabrizio_et_al-2020-Cochrane_Database_of_Syste.pdf
PY  - 2020
T2  - Cochrane Database of Systematic Reviews
TI  - Individualized versus standard diet fortification for growth and development in preterm infants receiving human milk
ER  -
TY  - JOUR
AB  - This meta-analysis evaluated the effectiveness of available treatments for self-injury in adolescents. We chose eight between group studies (N = 446) that met our inclusion criteria. Results revealed small to large Hedge&#039;s g effect sizes for self-injury. Moderator analyses identified age, number of sessions, and depression effect size as factors that accounted for differences in treatment effect. Implications and suggestions for future research are discussed. (PsycInfo Database Record (c) 2021 APA, all rights reserved)
AD  - MichelleStephenHunnicutt Hollenbaugh, K. Michelle: michelle.hollenbaugh@tamucc.eduHunnicutt Hollenbaugh, K. Michelle, 6300 Ocean Drive, ECDC 151, Unit 5834, Corpus Christi, TX, US, 78412, michelle.hollenbaugh@tamucc.eduHunnicutt Hollenbaugh, K. Michelle: Department of Counseling and Educational Psychology, Texas A&amp;M University, Corpus Christi, TX, USLenz, A. Stephen: Department of Counseling and Educational Psychology, Texas A&amp;M University, Corpus Christi, TX, USMincey, Kimberlee A.: Department of Counseling and Educational Psychology, Texas A&amp;M University, Corpus Christi, TX, USDyurich, Adriana: Department of Counseling and Educational Psychology, Texas A&amp;M University, Corpus Christi, TX, US
AN  - 2020-09291-001
AU  - Hunnicutt
AU  - Hollenbaugh,
AU  - K.
AU  - Lenz,
AU  - A.
AU  - Mincey,
AU  - K.
AU  - A.
AU  - Dyurich,
AU  - A.
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/23727810.2019.1686324
DP  - Ovid Technologies
KW  - self-injury, adolescents, meta-analysis
KW  - *Self-Injurious Behavior
KW  - *Treatment Effectiveness Evaluation
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human
L1  - internal-pdf://0354512880/Hunnicutt Hollenbaugh-2020.pdf
LA  - English
M3  - Meta Analysis
PY  - 2020
SP  - 54-69
T2  - Journal of Child and Adolescent Counseling
TI  - Preliminary analysis of the effectiveness of self-injury treatments for adolescents
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2020-09291-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F23727810.2019.1686324&amp;issn=2372-7810&amp;isbn=&amp;volume=6&amp;issue=1&amp;spage=54&amp;pages=54-69&amp;date=2020&amp;title=Journal+of+Child+and+Adolescent+Counseling&amp;atitle=Preliminary+analysis+of+the+effectiveness+of+self-injury+treatments+for+adolescents.&amp;aulast=Hunnicutt+Hollenbaugh&amp;pid=%3Cauthor%3EHunnicutt+Hollenbaugh%2C+K.+Michelle%3C%2Fauthor%3E%3CAN%3E2020-09291-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/full/10.1080/23727810.2019.1686324
UR  - https://www.tandfonline.com/doi/pdf/10.1080/23727810.2019.1686324?needAccess=true
VL  - 6
ER  -
TY  - JOUR
AB  - **INTRODUCTION:**
Preoperative anxiety and postoperative pain are common problems in patients undergoing surgery. The aim of this study is to analyse the effect of using guided imagery prior to surgery in adults and children to reduce preoperative anxiety and acute postoperative pain, compared with conventional preoperative nursing care.

**METHODS:** 
A systematic review and meta-analysis were conducted. We searched randomised clinical trials in databases and search engines.

**RESULTS:**
A total of 1101 records were identified, of which 21 were included in the qualitative synthesis. Two random model meta-analysis were performed with eight trials. Guided imagery preoperatively was shown to be effective in relieving preoperative state anxiety in children (d = -3.71), preoperative trait anxiety in adults (d = -0.64) and postoperative pain in adults (d = -0.24). Postoperative pain in children and preoperative state anxiety in adults was reduced but without significant difference.

**CONCLUSION:**
Guided imagery preoperatively is an effective, easy and low-cost intervention.
AD  - Alvarez-Garcia, Cristina. Department of Nursing, University of Jaen, Campus Las Lagunillas, 23071, Building B3, Office 221, Jaen, Spain. Electronic address: cagarcia@ujaen.es.Yaban, Zuleyha Simsek. Department of Nursing, Faculty of Health Sciences, Kocaeli University, Kocaeli, Turkey.
AN  - 32056813
AU  - Alvarez-Garcia,
AU  - C.
AU  - Yaban,
AU  - Z.
AU  - S.
DA  - Feb
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.ctcp.2019.101077
DP  - Ovid Technologies
J2  - Complement Ther Clin Pract
L1  - internal-pdf://0250646205/Alvarez-Garcia-2020-The effects of preoperativ.pdf
LA  - English
M3  - Review
N1  - Alvarez-Garcia, CristinaYaban, Zuleyha SimsekS1744-3881(19)30581-X
PY  - 2020
T2  - Complementary Therapies in Clinical Practice
TI  - The effects of preoperative guided imagery interventions on preoperative anxiety and postoperative pain: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32056813
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32056813&amp;id=doi:10.1016%2Fj.ctcp.2019.101077&amp;issn=1744-3881&amp;isbn=&amp;volume=38&amp;issue=&amp;spage=101077&amp;pages=101077&amp;date=2020&amp;title=Complementary+Therapies+in+Clinical+Practice&amp;atitle=The+effects+of+preoperative+guided+imagery+interventions+on+preoperative+anxiety+and+postoperative+pain%3A+A+meta-analysis.&amp;aulast=Alvarez-Garcia&amp;pid=%3Cauthor%3EAlvarez-Garcia+C%3C%2Fauthor%3E%3CAN%3E32056813%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/273294/1-s2.0-S1744388119X00055/1-s2.0-S174438811930581X/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjECYaCXVzLWVhc3QtMSJHMEUCIDH4UsMEDXmbj8uDCyQLLa%2Fvpjk5WfPXINQ9DKD7LMJpAiEA2iFbg%2FYZ62k5V5LdId6m2iweZNGYf2LaTQIpDMqWolkqvQMI%2F%2F%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FARACGgwwNTkwMDM1NDY4NjUiDCfIloAq2n5pZHnntSqRA5DW22C7FYF61oFX3XSk29L2LRLZWlvJD8mPvSON%2FEfLcbpNFDEBqFw8KIaToEQTWZT9RIE1vPRWSNAH6nUjGvgmsN9mmxrYhr31d9v5HqThBGF9n4KmNVExoAbFDapvwWJp7N3XJYT8YmQ%2FUP28Q3wjEZR824KkNamDLV3jAzY2jd25Rx1x05Q24zPTxwRZyaLbIZxs6fJ%2FiLIuWymLCeHnETesudWNTVw6g4DPCrWTWlaVNE6PmtxS%2FMkBjFaj9l1MZt1aB3NRSnGdLevT3L5xiX6nRezQ9nYDXEuDpjpE43o%2Bp60CpNB%2Bzxu0vKYB2Ik8PLCoFgJb9%2FpqIiF622fUQ6DGb5y9S%2BBHkBEE%2FPBB3sDGh3j3sYNdULV76L9o21OjVbS5RwhExcm9jDVpW08%2F4c1Rl6djDv5guO6c2uz55rqNQyflvx33dIf0ndxSXqWUu7%2FZL1HWASsUNaHe9F7U7w1GxKchaWVKMFbHsc6g3bk2wdqr7YvR7mEgkTzDywHqce3KV9lp%2BnHskllzhztkMKX5ofMFOusB9KjrQSYtQXaXuS4TNpXjjne7cjfeef918YZ8SV0ioWlh0jnmJUDQAjvsGlGWwQ8OyLmTQQNNrmEbwEuBcfGTrTXYQxD1hoQKQqZvlGAJe2ufwdTeHdYugCJsI%2BToujP3H0lWEBWMpp3b6Ka0D5%2Fxqs2QHEB5OGNLOLWtxXHh9Jtjw0EFwITHruZS37byxkL6%2FgMjaXufdO64Y2%2Bxz3h0CjCqqGciWiXn%2BDfR5soK24z1ZTaz0kfB%2BUpyHonDYUD2w%2F2OELThNvmKBxnYKgVPA%2BPHDbYOFtwSRxtjDdw3H%2F3KvrMSTt08KrI1hg%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200311T073352Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYZWUZY2HK%2F20200311%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=60eea1eed44408d1cbc53911b55d37d8bd02cd274eb8ccdae6d12e8c25cef5eb&amp;hash=223bd7a26eb41d80f28cc83948f5c683099f24e8b0b8d64f7fff0670794ad554&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S174438811930581X&amp;tid=spdf-717944ab-4c88-4fbc-906f-b0dabc73065e&amp;sid=8321b27350baf84ef38be4a5b7ace7a282e9gxrqb&amp;type=client
VL  - 38
ER  -
TY  - JOUR
AB  - In this study, we evaluated the efficacy of mindfulness-based stress reduction (MBSR) for young people with anxiety symptoms. We used many databases, including PubMed, PsycINFO, Web of Science, EMBASE, CINAHL and Cochrane Library (from inception to May 2019). We included randomized controlled trials (RCTs) comparing MBSR with various control conditions, including didactic lecture course, health education, treatment as usual, didactic seminar and cognitive behavioral program in young people with anxiety symptoms. Finally, we selected fourteen studies comprising 1489 participants comparing with control conditions. The meta-analysis suggested that MBSR significantly reduced anxiety symptoms compared to control conditions at post-treatment (Standardized Mean Difference, SMD = -0.14, 95% CI -0.24 to -0.04). However, the effect of MBSR on anxiety symptoms in young people may be affected by different intervention duration, especially the significance in a short-term intervention (less than 8 weeks). In addition, the meta-analysis indicated publication bias for anxiety symptoms. Using the trim-and-fill method, we found the adjusted standardized mean difference, which indicated that MBSR was still significantly superior to the other control conditions. The sensitivity analysis showed that the result was reliable. Current evidence indicates MBSR has superior efficacy compared with control conditions in treating young people with anxiety symptoms. Based on this, we suggest there is a significant effect of MBSR on young people with anxiety symptoms, especially the effects of long-term intervention for future studies.
AN  - WOS:000558423200003
AU  - Zhou,
AU  - X.
AU  - Guo,
AU  - J.
AU  - Y.
AU  - Lu,
AU  - G.
AU  - L.
AU  - Chen,
AU  - C.
AU  - R.
AU  - Xie,
AU  - Z.
AU  - X.
AU  - Liu,
AU  - J.
AU  - M.
AU  - Zhang,
AU  - C.
AU  - N.
DA  - Nov
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.psychres.2020.113002
L1  - internal-pdf://2250156930/Zhou-2020.pdf
N1  - Zhou, Xiang Guo, Jieyu Lu, Guangli Chen, Chaoran Xie, Zhenxing Liu, Jiangmin Zhang, Chuning
PY  - 2020
T2  - Psychiatry Research
TI  - Effects of mindfulness-based stress reduction on anxiety symptoms in young people: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000558423200003
UR  - https://www.sciencedirect.com/science/article/abs/pii/S0165178119317482?via%3Dihub
VL  - 289
ER  -
TY  - JOUR
AB  - A significant clinical issue encountered after a successful acute major depressive disorder (MDD) treatment is the relapse of depressive symptoms. Although continuing maintenance therapy with antidepressants is generally recommended, there is no established protocol on whether or not it is necessary to prescribe the antidepressant used to achieve remission. In this meta-analysis, the risk of relapse and treatment failure when either continuing with the same drug used to achieved remission or switching to a placebo was assessed in several clinically significant subgroups. The pooled odds ratio (OR) (+/-95% confidence intervals (CI)) was calculated using a random effects model. Across 40 studies (n = 8890), the relapse rate was significantly lower in the antidepressant group than the placebo group by about 20% (OR = 0.38, CI: 0.33-0.43, p &lt; 0.00001; 20.9% vs 39.7%). The difference in the relapse rate between the antidepressant and placebo groups was greater for tricyclics (25.3%; OR = 0.30, CI: 0.17-0.50, p &lt; 0.00001), SSRIs (21.8%; OR = 0.33, CI: 0.28-0.38, p &lt; 0.00001), and other newer agents (16.0%; OR = 0.44, CI: 0.36-0.54, p &lt; 0.00001) in that order, while the effect size of acceptability was greater for SSRIs than for other antidepressants. A flexible dose schedule (OR = 0.30, CI: 0.23-0.48, p &lt; 0.00001) had a greater effect size than a fixed dose (OR = 0.41, CI: 0.36-0.48, p &lt; 0.00001) in comparison to placebo. Even in studies assigned after continuous treatment for more than 6 months after remission, the continued use of antidepressants had a lower relapse rate than the use of a placebo (OR = 0.40, CI: 0.29-0.55, p &lt; 0.00001; 20.2% vs 37.2%). The difference in relapse rate was similar from a maintenance period of 6 months (OR = 0.41, CI: 0.35-0.48, p &lt; 0.00001; 19.6% vs 37.6%) to over 1 year (OR = 0.35, CI: 0.29-0.41, p &lt; 0.00001; 19.9% vs 39.8%). The all-cause dropout of antidepressant and placebo groups was 43% and 58%, respectively, (OR = 0.47, CI: 0.40-0.55, p &lt; 0.00001). The tolerability rate was ~4% for both groups. The rate of relapse (OR = 0.32, CI: 0.18-0.64, p = 0.0010, 41.0% vs 66.7%) and all-cause dropout among adolescents was higher than in adults. To prevent relapse and treatment failure, maintenance therapy, and careful attention for at least 6 months after remission is recommended. SSRIs are well-balanced agents, and flexible dose adjustments are more effective for relapse prevention.
AD  - Kato, Masaki. Department of Neuropsychiatry, Kansai Medical University, Osaka, Japan. katom@takii.kmu.ac.jp.Hori, Hikaru. Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Japan.Inoue, Takeshi. Department of Psychiatry, Tokyo Medical University, Tokyo, Japan.Iga, Junichi. Department of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, Japan.Iwata, Masaaki. Department of Neuropsychiatry, Faculty of Medicine, Tottori University, Yonago, Japan.Inagaki, Takahiko. Adolescent Mental Health Service, Biwako Hospital, Otsu, Japan.Inagaki, Takahiko. Department of Psychiatry, Shiga University of Medical Science, Otsu, Japan.Shinohara, Kiyomi. Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine and School of Public Health, Kyoto, Japan.Imai, Hissei. Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine and School of Public Health, Kyoto, Japan.Murata, Atsunobu. Department of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira, Japan.Mishima, Kazuo. Department of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.Tajika, Aran. Department of Psychiatry, Kyoto University Hospital, Kyoto, Japan.
AN  - 32704061
AU  - Kato,
AU  - M.
AU  - Hori,
AU  - H.
AU  - Inoue,
AU  - T.
AU  - Iga,
AU  - J.
AU  - Iwata,
AU  - M.
AU  - Inagaki,
AU  - T.
AU  - Shinohara,
AU  - K.
AU  - Imai,
AU  - H.
AU  - Murata,
AU  - A.
AU  - Mishima,
AU  - K.
AU  - Tajika,
AU  - A.
DA  - Jul 23
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1038/s41380-020-0843-0
DP  - Ovid Technologies
J2  - Mol Psychiatry
L1  - internal-pdf://3065676513/Kato-2020-Discontinuation of antidepressants a.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingJulKato, MasakiHori, HikaruInoue, TakeshiIga, JunichiIwata, MasaakiInagaki, TakahikoShinohara, KiyomiImai, HisseiMurata, AtsunobuMishima, KazuoTajika, Aran
PY  - 2020
SP  - 23
T2  - Molecular Psychiatry
TI  - Discontinuation of antidepressants after remission with antidepressant medication in major depressive disorder: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=32704061
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32704061&amp;id=doi:10.1038%2Fs41380-020-0843-0&amp;issn=1359-4184&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Molecular+Psychiatry&amp;atitle=Discontinuation+of+antidepressants+after+remission+with+antidepressant+medication+in+major+depressive+disorder%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Kato&amp;pid=%3Cauthor%3EKato+M%3C%2Fauthor%3E%3CAN%3E32704061%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.nature.com/articles/s41380-020-0843-0.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - **Background:** 
Intensive Family Preservation Services (IFPS) are in-home crisis intervention services designed to help families with children at imminent risk of out-of-home placement. 

**Objectives:** 
To assess the evidence of the effectiveness and cost-effectiveness of IFPS in reducing the need for children to enter out-of-home care. 

**Participants and setting:** 
Children &lt;18 years and their families in the home setting. 

**Methods:** 
A systematic review and meta-analysis was carried out by searching 12 databases and 16 websites for publications up to January 2019. 

**Results:** 
1948 potentially relevant papers were identified, of which 37 papers, relating to 33 studies, met our inclusion criteria. Studies reported outcomes at child or family level. There were significant reductions in relative risk (RR) of out-of-home placements in children who received IFPS compared with controls at child level at three, six, 12 and 24 months&#039; follow-up (RR 0.57, 95 % CI 0.35 to 0.93, RR 0.51, 95 % CI 0.27 to 0.96, RR 0.60, 95 % CI 0.48 to 0.76, RR 0.51, 95 % CI 0.30 to 0.87 respectively). At family level, there was not a significant reduction in RR of placement. Economic evidence was limited to cost analyses or cost-cost offset analyses. 

**Conclusion:** 
The available evidence, at child level, suggests that IFPS are effective in preventing children from entering care up to 24 months after the intervention. Placement outcomes reported at family level did not demonstrate a significant reduction in out-of-home placements. The economic analyses suggest that IFPS could be cost-saving; however, evidence of cost-effectiveness generated by full economic evaluations is needed. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - Nurmatov, Ulugbek B.: NurmatovU@cardiff.ac.ukNurmatov, Ulugbek B.: Cardiff University, School of Medicine, Division of Population Medicine, Neuadd Meirionnydd, Heath Park, Cardiff, United Kingdom, CF14 4YS, NurmatovU@cardiff.ac.ukBezeczky, Zoe: Children&#039;s Social Care Research and Development Centre, School of Social Sciences, Cardiff University, Cardiff, United KingdomEl-Banna, Asmaa: Warwick Clinical Trials Unit, University of Warwick, Coventry, United KingdomPetrou, Stavros: Warwick Clinical Trials Unit, University of Warwick, Coventry, United KingdomKemp, Alison: Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, United KingdomScourfield, Jonathan: Children&#039;s Social Care Research and Development Centre, School of Social Sciences, Cardiff University, Cardiff, United KingdomForrester, Donald: Children&#039;s Social Care Research and Development Centre, School of Social Sciences, Cardiff University, Cardiff, United KingdomNurmatov, Ulugbek B.: Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, United Kingdom
AN  - 2020-18943-001
AU  - Bezeczky,
AU  - Zoe
AU  - El-Banna,
AU  - Asmaa
AU  - Petrou,
AU  - Stavros
AU  - Kemp,
AU  - Alison
AU  - Scourfield,
AU  - Jonathan
AU  - Forrester,
AU  - Donald
AU  - Nurmatov,
AU  - Ulugbek
AU  - B.
DA  - Apr
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.chiabu.2020.104394
DP  - Ovid Technologies
KW  - Intensive Family Preservation Services, social work, child protection, out-of-home care, systematic review, meta-analysis
KW  - *Child Welfare
KW  - *Crisis Intervention Services
KW  - *Family Preservation
KW  - *Protective Services
KW  - *Social Casework
KW  - Community &amp; Social Services [3373]
KW  - Human
L1  - internal-pdf://3209917577/Bezeczky-2020-Intensive family preservation se.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2020
T2  - Child Abuse &amp; Neglect Vol 102 2020, ArtID 104394
TI  - Intensive family preservation services to prevent out-of-home placement of children: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2020-18943-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.chiabu.2020.104394&amp;issn=0145-2134&amp;isbn=&amp;volume=102&amp;issue=&amp;spage=104394&amp;pages=&amp;date=2020&amp;title=Child+Abuse+%26+Neglect&amp;atitle=Intensive+family+preservation+services+to+prevent+out-of-home+placement+of+children%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Bezeczky&amp;pid=%3Cauthor%3EBezeczky%2C+Zoe%3C%2Fauthor%3E%3CAN%3E2020-18943-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/271783/1-s2.0-S0145213420X00020/1-s2.0-S0145213420300491/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEK7%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQDYcTt49U4yjb4bx6wpBA6xLfCXTTbA6Lre4XsRlEeo8AIhANDOSoKBzdub2duW4mdBQ5pJoPS1I8xdy17c0yzSp3rXKrQDCCcQAxoMMDU5MDAzNTQ2ODY1IgzZhx5eO7211l70d%2FwqkQNDawqAWOaucLoaGn0txbvEQ%2FKV1nuj9apfA2mwExMlpr1JnK8G2F45ayFq7nKi9QhjdCfs4I6MtRdwGappjTiyIr0EwzsYqlHPZiZ3jmC7niSI84g6%2BF7Tpz08hoXeScDT3KPGbZbXgVFP3htOt8BE8KcDJgKkwTHMY6pVP4IR9lAh%2BHE8IuEADn2L6yqaG03fPJJOgZ4Sv63zHo7r1Q5Rxem9wrtwYGqgpTwp4R7PtPtZGrb3Gm%2FeI5HT0dLG3KlWkPBCOSp3t5LSsq9LmzYtltmUulTGwnTr9GDwdeqvA0dSTfhWxgbiEIK2VIEbO3jkwVpZI2dv1BqZ47nGf0pa%2FjGZtG7WBdneDd9zDyzI6ujWBE%2BQLBa%2BzQgg6aK8s3ndbGEC5FtgIjf1Pru0TO59o1p2Nc8eEdEwO9Sm%2Fq%2BcdTKY%2Blbu9Isv%2BzATT8kcQ4V8LXHwzBZ%2FwUlizvBSTPLjHnKt%2B8VKAxjd8m9AuQoZqt%2BKQfSnQQVojWzVKq29wAYHaV8kSaDRyQtXoPwo%2BlwGOjCG7YH3BTrqATxfdP4hXVdY%2BoSUs1HbplOgqZXexvTyHkd%2FfpG3UXWllqZmjWMY9AHKNdgD4OqqCbbKEATYNxg5jwZPoLi40J1bktAmweNI%2B9Qh8i%2B7zc%2B8ggVc4ATAqdPhNUi6A%2FOdlzVME9%2FjxVw0eqtX3qRkRBw9ncxXYNh6PfGQ%2BFbfZF46n4b7RTTOcktkxZaeNtnXu%2BjB9XUklmTYw4IENzcnOBoSjwfT8br6Rso2%2FwhlPLb%2FzFeVldAD5rJflnT338TMyU4ojyijNLZuMf3cjJL3lkWHuoDtvykGYy1X016SS2RIVMN6ZJiBrfZeWg%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200610T065323Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY2W7SARAT%2F20200610%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=0c45f7fb6f997867a24312b0ae0ac98fb2e088761c6c0371726b294e8d93c991&amp;hash=0fbd24d3e16d5ca0933384ab7d456a8203ec7b9769ccd41eeb12c952dd6e3fa4&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0145213420300491&amp;tid=spdf-71eaa607-7926-4428-9c3b-72e37c661cc6&amp;sid=b6715d5b8d7fc143477ae8442de16298848bgxrqb&amp;type=client
VL  - 102
ER  -
TY  - JOUR
AB  - **Background:** 
Loneliness is common among youth and is associated with poor physical and mental health, and poor educational outcomes. To date, there have been no meta-analyses of interventions aimed at reducing loneliness among young people.

**Method(s):** 
We conducted meta-analyses of single group and randomised control trials (RCTs) of studies published between 1980 and 2019, which measured loneliness as an outcome in youth ages 25 years or younger. Moderators, including sample demographics and intervention characteristics, that might affect intervention success, were examined. 

**Result(s):** 
A total of 39 studies (14 single group and 25 RCTs) were included, and we found evidence that youth loneliness could be reduced via intervention. Moderator analysis - including intervention characteristics, study quality and sample demographics - was also examined. 

**Conclusion(s):** 
While interventions were shown to reduce loneliness among youth, the interventions included in the meta-analyses often targeted youth viewed to be at risk - for example those with health concerns - and rarely did the interventions target youth who reported loneliness. There is also no indication of whether youth experienced chronic or transient loneliness. In future work, interventions should be designed specifically for loneliness, with universal programmes helping youth manage their transient feelings of loneliness, and targeted interventions for those suffering from chronic loneliness. There is also a need to look at socioeconomic and other risk factors outside the individual for targeted interventions. Copyright &copy; 2020 The Authors. Child and Adolescent Mental Health published by John Wiley &amp; Sons Ltd on behalf of Association for Child and Adolescent Mental Health.
AD  - (Eccles) Department of Psychology, University of Central Lancashire, Preston, Lancashire, United Kingdom (Eccles, Qualter) Manchester Institute of Education, University of Manchester, Manchester, United KingdomA.M. Eccles, Department of Psychology, University of Central Lancashire, Preston, Lancashire, United Kingdom. E-mail: AEccles1@uclan.ac.uk
AU  - Eccles,
AU  - A.
AU  - M.
AU  - Qualter,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/camh.12389
KW  - adolescents
KW  - children
KW  - interventions
KW  - Loneliness
KW  - meta-analysis
KW  - review
KW  - demography
KW  - human
KW  - human experiment
KW  - juvenile
KW  - meta analysis
KW  - outcome assessment
KW  - randomized controlled trial (topic)
KW  - risk factor
KW  - systematic review
L1  - internal-pdf://3680860164/Eccles-2020.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - Child and Adolescent Mental Health.
TI  - Review: Alleviating loneliness in young people - a meta-analysis of interventions
UR  - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1475-3588
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2004908981
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1111%2Fcamh.12389&amp;issn=1475-357X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Child+and+Adolescent+Mental+Health&amp;atitle=Review%3A+Alleviating+loneliness+in+young+people+-+a+meta-analysis+of+interventions&amp;aulast=Eccles&amp;pid=%3Cauthor%3EEccles+A.M.%3C%2Fauthor%3E%3CAN%3E2004908981%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://acamh.onlinelibrary.wiley.com/doi/full/10.1111/camh.12389
ER  -
TY  - JOUR
AB  - BACKGROUND: Exercise may be a promising target for depression interventions. However, evidence for a beneficial effect of exercise interventions on the prevention of depression differs substantially across different studies.

METHODS: A systematic search was performed up to July 2018 using PubMed, Embase, PsycINFO, and Cochrane. Articles were included if a meta-analysis of randomized controlled trials was performed that examined the effect of exercise interventions on the onset of depression or depressive symptoms in the general population. Meta-analyses focusing on treatment of diagnosed depression were excluded. Two authors independently screened the articles and graded the quality of included meta-analyses using AMSTAR 2.

RESULTS: Eight meta-analyses were included that showed little overlap in 134 included studies. All meta-analyses reported on depressive symptoms rather than onset of depression. Five of these were rated as moderate quality and three of low quality. Six meta-analyses found significant effects, and two found non-significant effects of exercise interventions in reducing depressive symptoms in children, adolescents, adults and the elderly (effect sizes ranging from - 0.10 to - 0.81). Scarce evidence did not allow to draw conclusions about the role of sex and characteristics of exercise on depression. However, some findings suggest that low intensity exercise was as effective as high intensity exercise. Heterogeneity among primary studies was high, likely caused by differences in study quality and exercise characteristics.

CONCLUSIONS: The evidence from this study suggests that exercise interventions have a beneficial effect on depressive symptoms in the general population across a wide age-range.
AD  - Hu, Mandy X. Department of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Oldenaller 1, 1081 HJ, Amsterdam, The Netherlands. x.hu@113.nl.Turner, David. Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, The Netherlands.Generaal, Ellen. Department of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Oldenaller 1, 1081 HJ, Amsterdam, The Netherlands.Bos, Daniel. Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.Bos, Daniel. Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.Ikram, M Kamran. Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.Ikram, M Arfan. Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.Cuijpers, Pim. Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, The Netherlands.Penninx, Brenda W J H. Department of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Oldenaller 1, 1081 HJ, Amsterdam, The Netherlands.
AN  - 32811468
AU  - Hu,
AU  - M.
AU  - X.
AU  - Turner,
AU  - D.
AU  - Generaal,
AU  - E.
AU  - Bos,
AU  - D.
AU  - Ikram,
AU  - M.
AU  - K.
AU  - Ikram,
AU  - M.
AU  - A.
AU  - Cuijpers,
AU  - P.
AU  - Penninx,
AU  - Bwjh
DA  - Aug 18
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/s12889-020-09323-y
DP  - Ovid Technologies
J2  - BMC Public Health
L1  - internal-pdf://2656056020/Hu-2020-Exercise interventions for the prevent.pdf
LA  - English
N1  - Hu, Mandy XTurner, DavidGeneraal, EllenBos, DanielIkram, M KamranIkram, M ArfanCuijpers, PimPenninx, Brenda W J H
PY  - 2020
SP  - 1255
T2  - BMC Public Health
TI  - Exercise interventions for the prevention of depression: a systematic review of meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=32811468
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:32811468&amp;id=doi:10.1186%2Fs12889-020-09323-y&amp;issn=1471-2458&amp;isbn=&amp;volume=20&amp;issue=1&amp;spage=1255&amp;pages=1255&amp;date=2020&amp;title=BMC+Public+Health&amp;atitle=Exercise+interventions+for+the+prevention+of+depression%3A+a+systematic+review+of+meta-analyses.&amp;aulast=Hu&amp;pid=%3Cauthor%3EHu+MX%3C%2Fauthor%3E%3CAN%3E32811468%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436997/pdf/12889_2020_Article_9323.pdf
VL  - 20
ER  -
TY  - JOUR
AB  - **Background:** 
Theraplay is a relationship-focused model of treatment based on attachment theory involving both adult and child. The study aims to review the quality of Theraplay research and Theraplay&#039;s effectiveness for children aged 12 years and under with a range of presenting difficulties, to inform future practice and identify areas for further research. 

**Method(s):** 
A systematic literature search was conducted using PsycINFO, CINAHL, MEDLINE and Web of Science. Quantitative studies using Theraplay only as a treatment for children aged 12 years and under with any presenting difficulty were identified. Additional manual searching was conducted, including eligible studies&#039; reference lists. Critical appraisal tools were used to provide a narrative synthesis of Theraplay&#039;s effectiveness and research quality. 

**Result(s):** 
Only six eligible articles were identified, meaning there was a lack of rigorous evidence eligible to offer conclusions into Theraplay&#039;s effectiveness. The review highlighted the small evidence base, mixed quality research methodology and high levels of heterogeneity in how Theraplay is practiced and evaluated. Of the eligible studies, Theraplay was found promising in its effectiveness when used with internalising and externalising difficulties, dual diagnoses and developmental disabilities. 

**Conclusion(s):** 
Theraplay is regularly practiced across the world; however, the evidence base of rigorous research to inform Theraplay&#039;s effectiveness and mechanisms of change is lacking. Firm conclusions could not be offered, although Theraplay was shown to be promising intervention for some presentations. Further research into Theraplay&#039;s effectiveness and key mechanisms of change are recommended to enhance the quality and depth of Theraplay literature. 
Copyright &copy; 2020 Association for Child and Adolescent Mental Health.
AD  - (Money, Wilde, Dawson) School of Psychology, Doctorate in Clinical Psychology (DClinPsy), University of Lincoln, Lincoln, United KingdomR. Money, School of Psychology, Doctorate in Clinical Psychology (DClinPsy), University of Lincoln, Lincoln, United Kingdom. E-mail: 16662523@students.lincoln.ac.uk
AN  - 2005781230
AU  - Money,
AU  - R.
AU  - Wilde,
AU  - S.
AU  - Dawson,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1111/camh.12416
DP  - Ovid Technologies
KW  - Behaviour problems
KW  - emotional dysregulation
KW  - mental health
KW  - parent-child interaction
KW  - play therapy
KW  - child
KW  - Cinahl
KW  - developmental disorder
KW  - female
KW  - human
KW  - male
KW  - Medline
KW  - narrative
KW  - problem behavior
KW  - PsycINFO
KW  - review
KW  - school child
KW  - synthesis
KW  - systematic review
KW  - Web of Science
L1  - internal-pdf://0608647313/Money-2020-Review_ The effectiveness of Therap.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingDate of Publication: 2020
PY  - 2020
T2  - Child and Adolescent Mental Health.
TI  - Review: The effectiveness of Theraplay for children under 12 - a systematic literature review
UR  - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1475-3588
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2005781230
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:32767491&amp;id=doi:10.1111%2Fcamh.12416&amp;issn=1475-357X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2020&amp;title=Child+and+Adolescent+Mental+Health&amp;atitle=Review%3A+The+effectiveness+of+Theraplay+for+children+under+12+-+a+systematic+literature+review&amp;aulast=Money&amp;pid=%3Cauthor%3EMoney+R.%3C%2Fauthor%3E%3CAN%3E2005781230%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://acamh.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/camh.12416?download=true
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering av effektene for tiltaket Psykologisk førstehjelp. Artikkelen er en revisjon av en tidligere beskrivelse av det samme tiltaket i Ungsinn (Neumer &amp; Eng, 2013), men videreutviklet i henhold til Ungsinn sine nye prosedyrer og kriterier (Martinussen m. fl., 2019). Psykologisk førstehjelp (PF) er i hovedsak et selvhjelpsmateriell som retter seg mot barn og unge i alderen 8-18 år. Hovedmålet med PF er å forebygge psykiske vansker gjennom å bruke førstehjelpsskrinet for å håndtere vanskelige følelser og situasjoner.

METODE
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS og SweMed. I tillegg har vi innhentet informasjon fra tiltakseier i Norge.

RESULTATER
Resultatene er basert på en vurdering av tiltakets beskrivelse, relevante studier og informasjon knyttet til implementeringskvalitet. Tiltaket PF er enkelt, men godt fremstilt gjennom heftene som følger med i førstehjelpsskrinene og bygger på en solid teoretisk forankring knyttet til kognitiv atferdsterapi. Veilederen gir en god innføring i de viktigste elementene for gjennomføring av tiltaket i førstelinjetjenesten. Litteratursøket viste at det ikke foreligger noen effektstudier knyttet til PF slik tiltaket er beskrevet og vurdert i denne kunnskapsoppsummeringen. Implementeringskvaliteten er ikke tilfredsstillende i henhold til de kriteriene som vurderes i Ungsinn, særlig med tanke på manglende kvalitetssikring og monitorering/etterlevelse av gjennomføringen. Det er grunnlag til å tro at tiltaket utøves forskjellig avhengig av hvem som leverer det.

KONKLUSJON
Tiltaket fremstår som enkelt å ta i bruk, og med sine konkrete hjelpemidler (figurer og hjelpehånd) ser det ut til å appellere til de ulike tjenestene som jobber med barn og unge. For å kunne hevde at tiltaket er virksomt, er det nødvendig med effektstudier av god metodisk kvalitet, samt et økt fokus på implementeringskvalitet.

Psykologisk førstehjelp klassifiseres på evidensnivå 2 &ndash; Teoretisk begrunnet tiltak.
AU  - Rasmussen,
AU  - L-M.
AU  - P.,
AU  - Neumer,
AU  - S-P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2020
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Psykologisk førstehjelp (2.utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/psykologisk-forstehjelp-2-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - **Objective** 
To systematically evaluate evidence for the use of interventions based on appied behavior analysis (ABA) to manage various symptoms of children with autism spectrum disorder (ASD). 

**Methods**
Sensitivity analyses were conducted by removing any outlying studies and subgroup analyses were performed to compare the effectiveness of ABA and early start denver model (ESDM), picture exchange communication systems (PECS) and discrete trial training (DTT). 

**Results** 
14 randomized control trials of 555 participants were included in this meta-analysis. The overall standardized mean difference was d=-0.36 (95% CI-1.31, 0.58; Z=0.75, p=0.45) for autism general symptoms, d=0.11 (95% CI-0.31, 0.54; Z=0.52, p=0.60) for social-ization, d=0.30 (95% CI-0.02, 0.61; Z=1.84, p=0.07) for communication and d=-3.52 (95% CI-6.31,-0.72; Z=2.47, p=0.01) for expressive language, d=-0.04 (95% CI-0.44, 0.36; Z=0.20, p=0.84) for receptive language. Those results suggested outcomes of socialization, communication and expressive language may be promising targets for ABA-based interventions involving children with ASD. However, significant effects for the outcomes of autism general symptoms, receptive language, adaptive behavior, daily living skills, IQ, verbal IQ, nenverbal IQ, restricted and repetitive behavior, motor and cognition were not observed. 

**Conclusion** 
The small number of studies included in the present study limited the ability to make inferences when comparing ABA, ESDM, PECS and DTT interventions for children with ASD. Psychiatry Investig 2020;17(5):432-443. Copyright &copy; 2020 Korean Neuropsychiatric Association.
AD  - (Yu, Li, Li) Department of Child Rehabilitation, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China (Liang) Department of Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, ChinaQ. Yu, Department of Child Rehabilitation, The Fifth Affiliated Hospital of Zhengzhou University, No.3 Kangfuqian Street, Erqi District, Zhengzhou 450000, China. E-mail: yu.q1an@yandex.com
AN  - 2004417576
AU  - Yu,
AU  - Q.
AU  - Li,
AU  - E.
AU  - Li,
AU  - L.
AU  - Liang,
AU  - W.
DA  - May
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.30773/pi.2019.0229
DP  - Ovid Technologies
KW  - Applied behavior analysis
KW  - Autism
KW  - Children
KW  - Meta-analysis
KW  - adaptive behavior
KW  - article
KW  - behavior modification
KW  - child
KW  - comparative effectiveness
KW  - compulsion
KW  - controlled study
KW  - female
KW  - human
KW  - language
KW  - male
KW  - meta analysis
KW  - psychiatry
KW  - randomized controlled trial (topic)
KW  - sensitivity analysis
KW  - skill
KW  - socialization
KW  - mianserin
L1  - internal-pdf://3515317775/Yu-2020-Efficacy of interventions based on app.pdf
LA  - English
PY  - 2020
SP  - 432-443
T2  - Psychiatry Investigation
TI  - Efficacy of interventions based on applied behavior analysis for autism spectrum disorder: A meta-analysis
UR  - http://www.psychiatryinvestigation.org/upload/pdf/pi-2019-0229.pdf
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2004417576
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.30773%2Fpi.2019.0229&amp;issn=1738-3684&amp;isbn=&amp;volume=17&amp;issue=5&amp;spage=432&amp;pages=432-443&amp;date=2020&amp;title=Psychiatry+Investigation&amp;atitle=Efficacy+of+interventions+based+on+applied+behavior+analysis+for+autism+spectrum+disorder%3A+A+meta-analysis&amp;aulast=Yu&amp;pid=%3Cauthor%3EYu+Q.%3C%2Fauthor%3E%3CAN%3E2004417576%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://www.psychiatryinvestigation.org/upload/pdf/pi-2019-0229.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - The aim of this novel review and meta-analysis was to clarify the effects of group-based organised physical activity (OPA) for social and communicative outcomes in children with Autism Spectrum Disorder (ASD). Searches yielded 4347 articles. 

Eleven were identified for review and seven for meta-analysis. Pooled statistical results revealed a non-significant effect for communication (k = 4; g = 0.13, CI [- 0.12, 0.38], p = .13) and a significant small-medium improvement in overall social functioning (k = 6; g = 0.45, CI [0.19, 0.72], p = .001). 

Despite acknowledged limitations, these findings are important in the context of a growing clinical and consumer-driven demand for research that determines the role of OPA as a non-medical and inclusive treatment for children with ASD.
AN  - 31102193
AU  - Howells,
AU  - K.
AU  - Sivaratnam,
AU  - C.
AU  - May,
AU  - T.
AU  - Lindor,
AU  - E.
AU  - McGillivray,
AU  - J.
AU  - Rinehart,
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10803-019-04050-9
L1  - internal-pdf://0552768133/Howells-2019-Efficacy of Group-Based Organised.pdf
PY  - 2019
SP  - 17
T2  - Journal of Autism &amp; Developmental Disorders
TI  - Efficacy of Group-Based Organised Physical Activity Participation for Social Outcomes in Children with Autism Spectrum Disorder: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31102193
UR  - https://link.springer.com/article/10.1007%2Fs10803-019-04050-9
VL  - 17
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
The objective of this study was to review English and Chinese randomised controlled trials (RCTs) to determine the effects of family-centred care (FCC) interventions on preterm infants&#039; and parental outcomes in the neonatal intensive care units and to conduct a meta-analysis. 

**REVIEW METHOD USED: **
Systematic review and meta-analysis. 

**DATA SOURCES:** 
Medline, CINAHL, Embase, PsycINFO, BNI, and AMED and the Chinese databases CNKI and Wanfang Data were searched in April 2017 and updated in August 2018. 

**REVIEW METHODS: **
Only RCTs were included. Participants were preterm infants &lt;=37 weeks gestational age and parents. Interventions were related to FCC, and outcome measures were infant and parent clinical outcomes. Included studies were assessed for risk of bias using Cochrane Manual 5.1.0. Meta-analyses used mean differences (MDs), standardised mean differences (SMDs), or odds ratio (OR), followed by 95% confidence interval (CI). Heterogeneity was tested with Cochran&#039;s Q chi-squared test, tau-squared test, and inconsistency index (I&lt;sup&gt;2&lt;/sup&gt;). 

**RESULTS: **
Nineteen studies (10 from English and 9 from Chinese databases) were included; meta-analysis included 15 studies (7 English and 8 Chinese RCTs). Meta-analysis showed significant improvements in weight gain (7 studies: MD, 4.57; 95% CI, 2.80-6.34; P &lt; 0.001; I&lt;sup&gt;2&lt;/sup&gt; 94%); readmission (3 studies: OR, 0.23; 95% CI, 0.10-0.52; P &lt; 0.001; I&lt;sup&gt;2&lt;/sup&gt; = 0%); parent satisfaction (5 studies: OR, 11.20; 95% CI, 4.76-26.34; p &lt; 0.001; I&lt;sup&gt;2&lt;/sup&gt; = 0%); skills of parents (4 studies: SMD, 2.57; 95% CI, 2.19-2.96; P &lt; 0.001; I&lt;sup&gt;2&lt;/sup&gt; = 53%); knowledge of parents (4 studies: SMD, 2.74; 95% CI, 2.47-3.00; P &lt; 0.001; I&lt;sup&gt;2&lt;/sup&gt; = 0%); parental anxiety at follow-up (3 studies: SMD, -0.19; 95% CI, -0.28 to -0.09; P &lt; 0.001; I&lt;sup&gt;2&lt;/sup&gt; = 0%); parent depression at follow-up (2 studies: SMD, 0.37; 95% CI, -0.63 to -0.12; P = 0.004; I&lt;sup&gt;2&lt;/sup&gt; = 44%); and parental stress (3 studies: MD, -0.20; 95% CI, -0.26 to -0.13; P &lt; 0.001; I&lt;sup&gt;2&lt;/sup&gt; = 0%). No statistical differences were observed in neurobehavioural development (3 studies) and hospital length of stay (7 studies). 

**CONCLUSIONS: **
FCC interventions can improve weight gain and readmission in preterm infants as well as parent satisfaction, knowledge, and skills, and possibly long-term anxiety, depression, and stress. Developing standardised outcome sets for testing family-centred care interventions is recommended.
AN  - 30554939
AU  - Ding,
AU  - X.
AU  - Zhu,
AU  - L.
AU  - Zhang,
AU  - R.
AU  - Wang,
AU  - L.
AU  - Wang,
AU  - T.
AU  - T.
AU  - Latour,
AU  - J.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.aucc.2018.10.007
L1  - internal-pdf://0326086095/Ding-2019-Effects of family-centred care inter.pdf
PY  - 2019
SP  - 63-75
T2  - Australian Critical Care
TI  - Effects of family-centred care interventions on preterm infants and parents in neonatal intensive care units: A systematic review and meta-analysis of randomised controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30554939
UR  - https://ac.els-cdn.com/S1036731418301528/1-s2.0-S1036731418301528-main.pdf?_tid=905e9f4c-caaa-4bb2-bd85-1b65c2c7f550&amp;acdnat=1549447293_515999dee895086f14334b7b3a0a50af
VL  - 32
ER  -
TY  - JOUR
AB  - Background
This is the first update of a review published in 2015, Issue 1. Chronic pain is common during childhood and adolescence and is associated with negative outcomes, such as increased severity of pain, reduced function, and low mood. Psychological therapies, traditionally delivered face‐to‐face with a therapist, are efficacious at reducing pain intensity and disability. To address barriers to treatment access, such as distance and cost of treatment, technology is being used to deliver these psychological therapies remotely. Therapies delivered remotely, such as via the Internet, computer‐based programmes, and smartphone applications, can be used to deliver treatment to children and adolescents with chronic pain.

Objectives
To determine the efficacy of psychological therapies delivered remotely compared to waiting list, treatment as usual, or active control treatments, for the management of chronic pain in children and adolescents.

Search methods
We searched four databases (CENTRAL, MEDLINE, Embase, and PsycINFO) from inception to May 2018 for randomised controlled trials (RCTs) of remotely‐delivered psychological interventions for children and adolescents with chronic pain. We searched for chronic pain conditions including, but not exclusive to, headache, recurrent abdominal pain, musculoskeletal pain, and neuropathic pain. We also searched online trial registries, reference sections, and citations of included studies for potential trials.

Selection criteria
We included RCTs that investigated the efficacy of a psychological therapy delivered remotely via technology in comparison to an active, treatment as usual, or waiting‐list control. We considered blended treatments, which used a combination of technology and up to 30% face‐to‐face interaction. Interventions had to be delivered primarily via technology to be included, and we excluded interventions delivered via telephone. We included studies that delivered interventions to children and adolescents (up to 18 years of age) with a chronic pain condition or where chronic pain was a primary symptom of their condition (e.g. juvenile arthritis). We included studies that reported 10 or more participants in each comparator arm, at each extraction point.

Data collection and analysis
We combined all psychological therapies in the analyses. We split pain conditions into headache and mixed (non‐headache) pain and analysed them separately. We extracted pain severity/intensity, disability, depression, anxiety, and adverse events as primary outcomes, and satisfaction with treatment as a secondary outcome. We considered outcomes at two time points: first immediately following the end of treatment (known as &#039;post‐treatment&#039;), and second, any follow‐up time point post‐treatment between three and 12 months (known as &#039;follow‐up&#039;). We assessed risk of bias and all outcomes for quality using the GRADE assessment.

Main results
We found 10 studies with 697 participants (an additional 4 studies with 326 participants since the previous review) that delivered treatment remotely; four studies investigated children with headache conditions, one study was with children with juvenile idiopathic arthritis, one included children with sickle cell disease, one included children with irritable bowel syndrome, and three studies included children with different chronic pain conditions (i.e. headache, recurrent abdominal pain, musculoskeletal pain). The average age of children receiving treatment was 13.17 years.

We judged selection, detection, and reporting biases to be mostly low risk. However, we judged performance and attrition biases to be mostly unclear. Out of the 16 planned analyses, we were able to conduct 13 meta‐analyses. We downgraded outcomes for imprecision, indirectness of evidence, inconsistency of results, or because the analysis only included one study.

Headache conditions

For headache pain conditions, we found headache severity was reduced post‐treatment (risk ratio (RR) 2.02, 95% confidence interval (CI) 1.35 to 3.01); P &lt; 0.001, number needed to treat to benefit (NNTB) = 5.36, 7 studies, 379 participants; very low‐quality evidence). No effect was found at follow‐up (very low‐quality evidence). There were no effects of psychological therapies delivered remotely for disability post‐treatment (standardised mean difference (SMD) ‐0.16, 95% CI ‐0.46 to 0.13; P = 0.28, 5 studies, 440 participants) or follow‐up (both very low‐quality evidence). Similarly, no effect was found for the outcomes of depression (SMD ‐0.04, 95% CI ‐0.15 to 0.23, P = 0.69, 4 studies, 422 participants) or anxiety (SMD ‐0.08, 95% CI ‐0.28 to 0.12; P = 0.45, 3 studies, 380 participants) at post‐treatment, or follow‐up (both very low‐quality evidence).

Mixed chronic pain conditions

We did not find any beneficial effects of psychological therapies for reducing pain intensity post‐treatment for mixed chronic pain conditions (SMD ‐0.90, 95% CI ‐1.95 to 0.16; P = 0.10, 5 studies, 501 participants) or at follow‐up. There were no beneficial effects of psychological therapies delivered remotely for disability post‐treatment (SMD ‐0.28, 95% CI ‐0.74 to 0.18; P = 0.24, 3 studies, 363 participants) and a lack of data at follow‐up meant no analysis could be run. We found no beneficial effects for the outcomes of depression (SMD 0.04, 95% CI ‐0.18 to 0.26; P = 0.73, 2 studies, 317 participants) and anxiety (SMD 0.53, 95% CI ‐0.63 to 1.68; P = 0.37, 2 studies, 370 participants) post‐treatment, however, we are cautious of our findings as we could only include two studies in the analyses. We could not conduct analyses at follow‐up. We judged the evidence for all outcomes to be very low quality.

All conditions

Across all chronic pain conditions, six studies reported minor adverse events which were not attributed to the psychological therapies. Satisfaction with treatment is described qualitatively and was overall positive. However, we judged both these outcomes as very low quality.

Authors&#039; conclusions
There are currently a small number of trials investigating psychological therapies delivered remotely, primarily via the Internet. We are cautious in our interpretations of analyses. We found one beneficial effect of therapies to reduce headache severity post‐treatment. For the remaining outcomes there was either no beneficial effect at post‐treatment or follow‐up, or lack of evidence to determine an effect. Overall, participant satisfaction with treatment was positive. We judged the quality of the evidence to be very low, meaning we are very uncertain about the estimate. Further studies are needed to increase our confidence in this potentially promising field.
AN  - CD011118
AU  - Fisher,
AU  - E.
AU  - Law,
AU  - E.
AU  - Dudeney,
AU  - J.
AU  - Eccleston,
AU  - C.,
AU  - Palermo,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd011118.pub2
KW  - Abdominal Pain [psychology] [therapy]
KW  - Anxiety [therapy]
KW  - Arthritis, Juvenile [psychology] [therapy]
KW  - Chronic Pain [psychology] [therapy]
KW  - Cognitive Therapy [methods]
KW  - Depression [therapy]
KW  - Headache [psychology] [therapy]
KW  - Internet
KW  - Musculoskeletal Pain [psychology] [therapy]
KW  - Pain Management [methods]
KW  - Patient Satisfaction
KW  - Psychotherapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Recurrence
KW  - Relaxation Therapy [methods]
KW  - Telemedicine [methods]
KW  - Treatment Outcome
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Sympt
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD011118.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD011118.pub2/asset/CD011118.pdf?v=1&amp;t=iw7kz0yq&amp;s=a508b354bb776d27d7af8dc3d68ca907e4badf96
ER  -
TY  - JOUR
AB  - This meta-analysis examined the effects of early interventions on social communication outcomes for young children with autism spectrum disorder. 

A systematic review of the literature included 1442 children (mean age 3.55 years) across 29 studies. The overall effect size of intervention on social communication outcomes was significant (g = 0.36). 

The age of the participants was related to the treatment effect size on social communication outcomes, with maximum benefits occurring at age 3.81 years.
AN  - 30805766
AU  - Fuller,
AU  - E.
AU  - A.
AU  - Kaiser,
AU  - A.
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10803-019-03927-z
L1  - internal-pdf://3730031687/Fuller-2019-The Effects of Early Intervention.pdf
PY  - 2019
SP  - 25
T2  - Journal of Autism &amp; Developmental Disorders
TI  - The Effects of Early Intervention on Social Communication Outcomes for Children with Autism Spectrum Disorder: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30805766
UR  - https://link.springer.com/article/10.1007%2Fs10803-019-03927-z
VL  - 25
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Parenting interventions have important consequences for the wellbeing and emotional competences of parents and their children. Technology provides an opportunity with advantages for psychological intervention. The aim of this systematic review and meta-analysis is to analyze the characteristics and effectiveness of technology-based interventions for parents to promote children&#039;s physical health or psychological issues. 

**METHODS: **
We conducted a systematic review and meta-analysis for articles about parenting skills for prevention or treatment of children&#039;s physical or psychological concerns using technology. We explore the aim of the intervention with parents, kind of problem with children, intervention model, instruments, methodological quality, and risk of bias. A random-effects meta-analysis was conducted. 

**RESULTS:**
Twenty-four studies were included in the systematic review and a meta-analysis of 22 studies was performed to find out the effects of intervention depending on the kind of problem, intervention model, follow-up, type of intervention, type of control condition, and type of outcome data. Results show the usefulness of technology-based therapy for parenting interventions with moderate effect sizes for intervention groups with statistically significant differences from control groups. 

**CONCLUSIONS: **
Technology-based parenting programs have positive effects on parenting and emotional wellbeing of parents and children. Attendance and participation level in technology-based treatment increase compared with traditional parenting intervention.
AN  - 30977462
AU  - Flujas-Contreras,
AU  - J.
AU  - M.
AU  - Garcia-Palacios,
AU  - A.
AU  - Gomez,
AU  - I.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1017/S0033291719000692
L1  - internal-pdf://2188831982/Flujas-Contrera-2019-Technology-based parentin.pdf
PY  - 2019
SP  - 1-12
T2  - Psychological Medicine
TI  - Technology-based parenting interventions for children&#039;s physical and psychological health: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30977462
UR  - https://www.cambridge.org/core/journals/psychological-medicine/article/technologybased-parenting-interventions-for-childrens-physical-and-psychological-health-a-systematic-review-and-metaanalysis/2CE254BD582559376FD330EC4A3CB1D9
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Cognitive-behavioral therapy (CBT) is first choice of treatment for depressive symptoms and disorders in adolescents, however improvements are necessary because overall efficacy is low. Insights on CBT components and contextual and structural characteristics might increase the efficacy. The aim of our approach is to evaluate the efficacy of CBT for youth with depression and investigate the influence of specific components, contextual and structural factors that could improve effects. 

**METHODS: **
A systematic review of randomized controlled trials was conducted, searches were undertaken in CINAHL, CENTRAL, EMBASE, MEDLINE/PubMed and PsycINFO. Outcomes were meta-analyzed and confidence in results was assessed using the GRADE-method. Meta-regression was used to pinpoint components or other factors that were associated with an in- or decrease of effects of CBT. 

**RESULTS: **
We included 31 trials with 4335 participants. Moderate-quality evidence was found for CBT reducing depressive symptoms at the end of treatment and at follow-up, and CBT as indicated prevention resulted in 63% less risk of being depressed at follow-up. CBT containing a combination of behavioral activation and challenging thoughts component (as part of cognitive restructuring) or the involvement of caregiver(s) in intervention were associated with better outcomes for youth on the long term. 

**CONCLUSIONS: **
There is evidence that CBT is effective for youth with a (subclinical) depression. Our analyses show that effects might improve when CBT contains the components behavioral activation and challenging thoughts and also when the caregiver(s) are involved. However, the influential effects of these three moderators should be further tested in RCTs.
AN  - 30658278
AU  - Oud,
AU  - M.
AU  - de
AU  - Winter,
AU  - L.
AU  - Vermeulen-Smit,
AU  - E.
AU  - Bodden,
AU  - D.
AU  - Nauta,
AU  - M.
AU  - Stone,
AU  - L.
AU  - van
AU  - den
AU  - Heuvel,
AU  - M.
AU  - Taher,
AU  - R.
AU  - A.
AU  - de
AU  - Graaf,
AU  - I.
AU  - Kendall,
AU  - T.
AU  - Engels,
AU  - R.
AU  - Stikkelbroek,
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.eurpsy.2018.12.008
L1  - internal-pdf://2661790354/Oud-2019-Effectiveness of CBT for children and.pdf
PY  - 2019
SP  - 33-45
T2  - European Psychiatry: the Journal of the Association of European Psychiatrists
TI  - Effectiveness of CBT for children and adolescents with depression: A systematic review and meta-regression analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30658278
UR  - https://ac.els-cdn.com/S0924933818302256/1-s2.0-S0924933818302256-main.pdf?_tid=43655087-4182-441e-a5c9-852d3e5f1fb8&amp;acdnat=1549447404_e91f9b3adf1ff746a455ffc1ebe3e99a
VL  - 57
ER  -
TY  - JOUR
AB  - OBJECTIVE: To perform an umbrella review of systematic reviews and meta-analyses of health policy and health promotion strategies to reduce the tobacco demand in adolescents, youth and young adults.

METHODS: Reviewers independently performed an electronic database search, reviewed titles and abstracts, assessed articles&#039; eligibility for inclusion and quality, and extracted relevant data. Only systematic reviews and meta-analyses reporting data on tobacco policies and interventions focusing on individuals aged &lt;25 years were included. The Framework Convention on Tobacco Control was used to guide data synthesis.

RESULTS: 13 articles were included. Studies were of mixed quality with five studies ranked as critically low and seven as high quality. Overall, mixed results were found on the effectiveness for tobacco policies and interventions. Strategies such as increasing taxes on tobacco products were most promising.

CONCLUSION: Though data on a variety of measures to reduce smoking is available, conclusions concerning the effectiveness are inconclusive. Tobacco policies and interventions have the potential to reduce smoking, but conclusions are hampered due to both lack of high-quality trials and numerous biases in primary studies. Further high-quality research is required to examine the effectiveness of interventions and policies to reduce the tobacco demand in adolescents, youth and young adults.
AD  - Mannocci, Alice. Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.Backhaus, Insa. Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy. Electronic address: insa.backhaus@uniroma1.it.D&#039;Egidio, Valeria. Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.Federici, Antonio. Ministry of Health, Italy.Villari, Paolo. Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.La Torre, Giuseppe. Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.
AN  - 30922630
AU  - Mannocci,
AU  - A.
AU  - Backhaus,
AU  - I.
AU  - D&#039;Egidio,
AU  - V.
AU  - Federici,
AU  - A.
AU  - Villari,
AU  - P.
AU  - La
AU  - Torre,
AU  - G.
DA  - 05
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.healthpol.2019.02.009
DP  - Ovid Technologies
J2  - Health Policy
KW  - Adolescent
KW  - Child
KW  - Health Policy
KW  - Health Promotion/mt [Methods]
KW  - Humans
KW  - Smoke-Free Policy
KW  - Smoking/ec [Economics]
KW  - *Smoking/lj [Legislation &amp; Jurisprudence]
KW  - Smoking Cessation/lj [Legislation &amp; Jurisprudence]
KW  - *Smoking Cessation/mt [Methods]
KW  - *Smoking Prevention/mt [Methods]
KW  - Tobacco Products/ec [Economics]
KW  - Tobacco Products/lj [Legislation &amp; Jurisprudence]
KW  - Young Adult
L1  - internal-pdf://0114439477/Mannocci-2019.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
Review
N1  - Mannocci, AliceBackhaus, InsaD&#039;Egidio, ValeriaFederici, AntonioVillari, PaoloLa Torre, GiuseppeS0168-8510(19)30042-9
PY  - 2019
SP  - 480-491
T2  - Health Policy
TI  - What public health strategies work to reduce the tobacco demand among young people? An umbrella review of systematic reviews and meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=30922630
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30922630&amp;id=doi:10.1016%2Fj.healthpol.2019.02.009&amp;issn=0168-8510&amp;isbn=&amp;volume=123&amp;issue=5&amp;spage=480&amp;pages=480-491&amp;date=2019&amp;title=Health+Policy&amp;atitle=What+public+health+strategies+work+to+reduce+the+tobacco+demand+among+young+people%3F+An+umbrella+review+of+systematic+reviews+and+meta-analyses.&amp;aulast=Mannocci&amp;pid=%3Cauthor%3EMannocci+A%3C%2Fauthor%3E%3CAN%3E30922630%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 123
ER  -
TY  - JOUR
AB  - Depression contributes about 2% to the global burden of disease. A first onset of depressive disorder or subsyndromal depressive symptoms is common in adolescence, indicating that early prevention is a priority. However, trials of preventive interventions for depression in youths show conflicting results. 

This systematic review and meta-analysis investigated the effectiveness of group-based cognitive behavioral therapy (GB-CBT) as a preventive intervention targeting subsyndromal depression in children and adolescents. In addition, the impact of different covariates (type of comparator and use of booster sessions) was assessed. 

Relevant articles were identified from previous systematic reviews, and supplemented with an electronic search spanning from 01/09/2014 to 28/02/2018. The retrieved articles were assessed for eligibility and risk of bias. Relevant data were extracted. Intervention effectiveness was pooled using a random-effects model and the impact of covariates assessed using meta-regression. 38 eligible articles (34 trials) were obtained. 

The analysis showed GB-CBT to significantly reduce the incidence (relative risk 0.43, 95% CI 0.21-0.87) and symptoms (Cohen&#039;s d -0.22, 95% CI -0.32 to -0.11) of depression at post-test compared to all controls. Comparisons with passive comparators suggested that the effect decayed over time. However, compared to active controls, a significant intervention effect was evident only after 12month or more. 

Our results suggest that the preventive effect of GB-CBT wears off, but still lasts longer than the effect of active comparators. Only a few studies included booster sessions, precluding firm conclusions. Future studies should clarify to what extent maintenance strategies can prolong the preventive effect of GB-CBT.
AN  - 30287331
AU  - Ssegonja,
AU  - R.
AU  - Nystrand,
AU  - C.
AU  - Feldman,
AU  - I.
AU  - Sarkadi,
AU  - A.
AU  - Langenskiold,
AU  - S.
AU  - Jonsson,
AU  - U.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ypmed.2018.09.021
L1  - internal-pdf://2618537469/Ssegonja-2019-Indicated preventive interventio.pdf
PY  - 2019
SP  - 7-15
T2  - Preventive Medicine
TI  - Indicated preventive interventions for depression in children and adolescents: A meta-analysis and meta-regression
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30287331
UR  - https://ac.els-cdn.com/S0091743518302998/1-s2.0-S0091743518302998-main.pdf?_tid=ea2e5c66-bc87-4f38-8ebb-2785813db253&amp;acdnat=1549447451_a484852d6ebe64f3db1878b51d7b1365
VL  - 118
ER  -
TY  - JOUR
AB  - **Background**
Preterm infants have fewer nutrient reserves at birth than full‐term infants and often receive artificial formula feeds in the absence of expressed breast milk. Although it is generally agreed that feeding must be initiated slowly and advanced with much greater deliberation than in a healthy, full‐term infant, the way in which feeds are introduced and advanced in preterm infants varies widely. This review focuses on whether dilute or full‐strength formula is the preferable mode of introducing feeds in preterm infants for whom expressed breast milk is unavailable.

**Objectives**
To assess the effects of dilute versus full‐strength formula on the incidence of necrotising enterocolitis, feeding intolerance, weight gain, length of stay in hosptial and time to achieve full calorie intake in exclusively formula‐fed preterm or low birth weight infants. A secondary objective was to assess the effects of different dilution strategies.

**Search methods**
We used the standard search strategy of Cochrane Neonatal to update the search in the Cochrane Central Register of Controlled Trials (CENTRAL 2018, Issue 9), MEDLINE via PubMed (1966 to 1 October 2018), Embase (1980 to 1 October 2018), and CINAHL (1982 to 1 October 2018).We searched clinical trials&#039; registries for ongoing or recently completed trials (clinicaltrials.gov; the World Health Organization&rsquo;s International Trials Registry and Platform; and the ISRCTN Registry).

**Selection criteria**
Randomised or quasi‐randomised trials comparing strengths of formula milk in exclusively formula‐fed preterm or low birth weight infants. We excluded studies if infants received formula as a supplement to breast milk.

**Data collection and analysis**
We independently assessed studies for inclusion. We collected data using the standard methods of Cochrane Neonatal, with independent assessment of risk of bias and data extraction. We synthesised mean differences using a fixed‐effect meta‐analysis model. We used the GRADE approach to assess the certainty of evidence.

**Main results**
We included three studies involving 102 preterm or low birth weight infants in the review. The studies compared dilute (double‐volume, half‐strength) formula with full‐strength (20 kcal/oz (&tilde; 68 to 70 kcal/100 mL)) formula. We assessed all three studies as having unclear risk of bias due to the likely absence of blinding of study personnel and the potential for selection bias in the largest trial. Data for the primary outcome of necrotising enterocolitis were not reported in any of the studies. We could combine two of the studies (88 infants) in the meta‐analysis. The evidence suggests that dilute formula with double‐volume (half‐strength) may lead to fewer episodes of gastric residuals per day (one study; mean difference (MD) &minus;1.20, 95% confidence interval (CI) &minus;2.20 to &minus;0.20; low‐certainty evidence), fewer episodes of gastric residuals per baby until attaining 100 kcal/kg (one study; MD &minus;0.80, 95% CI &minus;1.32 to &minus;0.28; low‐certainty evidence), fewer episodes of vomiting per day (one study; MD &minus;0.04, 95% CI &minus;0.07 to &minus;0.01; low‐certainty evidence) and fewer occurrences of abdominal distension greater than 2 cm (two studies; MD &minus;0.16, 95% CI &minus;0.19 to &minus;0.13; low‐certainty evidence). For the secondary outcomes, data suggest that infants in the dilute formula with double‐volume (half‐strength) group may have attained an adequate energy intake earlier than infants in the full‐strength group (two studies; MD &minus;2.26, 95% CI &minus;2.85 to &minus;1.67; low‐certainty evidence). There was no evidence of a difference between groups for weight gain one week after commencement of intragastric feeds (one study; MD 0.05 kg, 95% CI &minus;0.06 to 0.15; low‐certainty evidence). Data were not reported for length of hospital stay.

**Authors&#039; conclusions**
There is low‐certainty evidence from three small, old trials that use of dilute formula in preterm or low birth weight formula‐fed infants may lead to an important reduction in the time taken for preterm infants to attain an adequate energy intake.However, our confidence in this result is limited due to uncertainty over risk of bias and sparsity of available data. Dilute formula may reduce incidence of feeding intolerance, but the clinical significance of the reduction is uncertain. The impact on serious gastrointestinal problems, including necrotising enterocolitis, was not reported in any of the trials. Further randomised trials are needed to confirm these results.
AU  - Basuki,
AU  - F.
AU  - Hadiati,
AU  - D.
AU  - R.
AU  - Turner,
AU  - T.
AU  - McDonald,
AU  - S.
AU  - Hakimi,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD007263.pub3
L1  - internal-pdf://3242313451/Basuki-2019-Dilute versus full‐strength formul.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Dilute versus full‐strength formula in exclusively formula‐fed preterm or low birth weight infants
ER  -
TY  - JOUR
AB  - Sleep problems are common in children, especially those with neurodevelopmental disorders, and can lead to consequences in behavior, functioning, and quality of life. 

We systematically reviewed the efficacy and harms of pharmacologic treatments for sleep disorders in children and adolescents. We searched MEDLINE, Cochrane library databases, and PsycINFO through June 2018. We included 22 placebo-controlled randomized controlled trials (1-13 weeks&#039; duration), involving 1758 children (mean age 8.2 years). 

Single randomized controlled trials of zolpidem and eszopiclone in children with attention-deficit/hyperactivity disorder (ADHD) showed no improvement in sleep or ADHD ratings. Clinical Global Impression Improvement/Severity scores significantly improved with zolpidem ( P = .03 and P = .006, respectively). 

A single, small randomized controlled trial of diphenhydramine reported small improvements in sleep outcomes (8-10 minutes&#039; better sleep latency and duration) after 1 week. In 19 randomized controlled trials, melatonin significantly improved sleep latency (median 28 minutes; range 11-51 minutes), sleep duration (median 33 minutes; range 14-68 minutes), and wake time after sleep onset (range 12-43 minutes), but not number of awakenings per night (range 0-2.7). 

Function and behavior improvement varied. Improvement in sleep was greatest in children with autism or other neurodevelopmental disorders, and smaller in adolescents and children with chronic delayed sleep onset. Adverse events were infrequent with melatonin, but more frequent than placebo in children taking eszopiclone or zolpidem. 

These findings show that melatonin was useful in improving some sleep outcomes in the short term, particularly those with comorbid ASD and neurodevelopmental disorders. Other drugs and outcomes are inadequately studied.
AN  - 30674203
AU  - McDonagh,
AU  - M.
AU  - S.
AU  - Holmes,
AU  - R.
AU  - Hsu,
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0883073818821030
L1  - internal-pdf://0628862728/McDonagh-2019-Pharmacologic Treatments for Sle.pdf
PY  - 2019
SP  - 883073818821030
T2  - Journal of Child Neurology
TI  - Pharmacologic Treatments for Sleep Disorders in Children: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30674203
ER  -
TY  - JOUR
AB  - **Purpose:** 
To examine the effects of short-term psychological interventions on reducing family stress of economically disadvantaged families. 

**Method:** 
Systematic review and meta-analytic procedures were used to synthesize the results of randomized controlled studies published between 1980 and 2018. 

**Results:** 
The search yielded 8 studies that included results for 1,538 families in total. The risk of bias varied across studies. The meta-analysis results suggest a small positive effect (g = .38, p &lt; .001) on child behavioral problems. Heterogeneity was relatively high and significant. We also found small to moderate effects on parenting stress, parental depression, and parenting quality (g ranging from .30 to .51). 

**Discussion:** 
The findings of this review suggest that short-term psychological interventions may reduce the family stress of economically disadvantaged families, with effect sizes that are comparable to those of interventions delivered to ordinary families. Implications for further research and practice are discussed.
AD  - [Lo, Herman Hay-Ming; Zhang, Jiwen; Choi, Chun-Wah] Hong Kong Polytech Univ, Dept Appl Social Sci, Hung Hom, Kowloon, Hong Kong, Peoples R China.Lo, HHM (reprint author), Hong Kong Polytech Univ, Dept Appl Social Sci, Hung Hom, Kowloon, Hong Kong, Peoples R China.herman.lo@polyu.edu.hk
AN  - WOS:000484373200001
AU  - Lo,
AU  - H.
AU  - H.
AU  - M.
AU  - Zhang,
AU  - J.
AU  - W.
AU  - Choi,
AU  - C.
AU  - W.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1177/1049731519870273
J2  - Res. Soc. Work. Pract.
KW  - psychological intervention
KW  - family stress theory
KW  - economically
KW  - disadvantaged families
KW  - meta-analysis
KW  - middle-income countries
KW  - randomized controlled-trial
KW  - socioeconomic-status
KW  - mental-health
KW  - parenting intervention
KW  - social
KW  - determinants
KW  - conduct problems
KW  - children
KW  - program
KW  - behavior
KW  - Social Work
L1  - internal-pdf://0089188701/Lo.pdf
LA  - English
M3  - Review; Early Access
N1  - ISI Document Delivery No.: IV6IXTimes Cited: 0Cited Reference Count: 66Lo, Herman Hay-Ming Zhang, Jiwen Choi, Chun-WahEarly Career Scheme, Research Grants Council, Hong Kong Special Administrative Region [21611415]The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported by the Early Career Scheme, Research Grants Council, Hong Kong Special Administrative Region (#21611415).0Sage publications incThousand oaks1552-7581
PY  - 2019
SP  - 14
T2  - Research on Social Work Practice
TI  - Short-Term Psychological Interventions on Economically Disadvantaged Families: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000484373200001
ER  -
TY  - JOUR
AB  - Perinatal anxiety and depression are common and associated with negative outcomes if left untreated. Internet-delivered treatments can improve treatment accessibility and have demonstrated effectiveness in treating anxiety and depression in the general adult population. However, little is known about how effective and acceptable these interventions are for perinatal women. This paper describes a systematic review and preliminary meta-analysis of internet-delivered psychological interventions for the treatment of clinical anxiety and depression in perinatal women. A systematic search was carried out of seven electronic databases. Seven studies evaluating six distinct internet-delivered psychological interventions were identified. Of the seven studies included, two were open trials and five were randomized controlled trials with a total of 595 participants. Preliminary findings indicate large improvements in depression (Hedges g = 1.67; 95% CI 1.38-1.96) and anxiety (Hedges g = 1.08; 95% CI 0.80-1.36) from pre- to post-treatment. However, between-group differences between interventions and control conditions were only moderate for depression (Hedges g = 0.60; 95% CI 0.43-0.78) and anxiety (Hedges g = 0.54; 95% CI 0.24-0.85). While our preliminary findings are promising, this review identifies an area of research still in its early stages with significant gaps in the literature that need to be addressed. Further research is needed to establish the efficacy and acceptability of these interventions in this population, especially for antenatal depression and anxiety disorders.
AD  - Loughnan, Siobhan A. Clinical Research Unit for Anxiety and Depression (CRUfAD), UNSW School of Psychiatry, Level 4, O&#039;Brien Centre, St Vincent&#039;s Hospital, 394 Victoria Street, Sydney, New South Wales, 2010, Australia. Siobhan.Loughnan@svha.org.au.Loughnan, Siobhan A. School of Psychiatry, University of New South Wales, Sydney, Australia. Siobhan.Loughnan@svha.org.au.Joubert, Amy E. Clinical Research Unit for Anxiety and Depression (CRUfAD), UNSW School of Psychiatry, Level 4, O&#039;Brien Centre, St Vincent&#039;s Hospital, 394 Victoria Street, Sydney, New South Wales, 2010, Australia.Joubert, Amy E. School of Psychology, University of New South Wales, Sydney, Australia.Grierson, Ashlee. Clinical Research Unit for Anxiety and Depression (CRUfAD), UNSW School of Psychiatry, Level 4, O&#039;Brien Centre, St Vincent&#039;s Hospital, 394 Victoria Street, Sydney, New South Wales, 2010, Australia.Grierson, Ashlee. School of Psychiatry, University of New South Wales, Sydney, Australia.Andrews, Gavin. Clinical Research Unit for Anxiety and Depression (CRUfAD), UNSW School of Psychiatry, Level 4, O&#039;Brien Centre, St Vincent&#039;s Hospital, 394 Victoria Street, Sydney, New South Wales, 2010, Australia.Andrews, Gavin. School of Psychiatry, University of New South Wales, Sydney, Australia.Newby, Jill M. Clinical Research Unit for Anxiety and Depression (CRUfAD), UNSW School of Psychiatry, Level 4, O&#039;Brien Centre, St Vincent&#039;s Hospital, 394 Victoria Street, Sydney, New South Wales, 2010, Australia.Newby, Jill M. School of Psychology, University of New South Wales, Sydney, Australia.
AN  - 31101993
AU  - Loughnan,
AU  - S.
AU  - A.
AU  - Joubert,
AU  - A.
AU  - E.
AU  - Grierson,
AU  - A.
AU  - Andrews,
AU  - G.
AU  - Newby,
AU  - J.
AU  - M.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00737-019-00961-9
DP  - Ovid Technologies
J2  - Arch Women Ment Health
L1  - internal-pdf://1072255094/Loughnan2019_Article_Internet-deliveredPsychol.pdf
LA  - English
N1  - Loughnan, Siobhan AJoubert, Amy EGrierson, AshleeAndrews, GavinNewby, Jill M
PY  - 2019
SP  - 737-750
T2  - Archives of Women&#039;s Mental Health
TI  - Internet-delivered psychological interventions for clinical anxiety and depression in perinatal women: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31101993
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31101993&amp;id=doi:10.1007%2Fs00737-019-00961-9&amp;issn=1434-1816&amp;isbn=&amp;volume=22&amp;issue=6&amp;spage=737&amp;pages=737-750&amp;date=2019&amp;title=Archives+of+Women%27s+Mental+Health&amp;atitle=Internet-delivered+psychological+interventions+for+clinical+anxiety+and+depression+in+perinatal+women%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Loughnan&amp;pid=%3Cauthor%3ELoughnan+SA%3C%2Fauthor%3E%3CAN%3E31101993%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs00737-019-00961-9
VL  - 22
ER  -
TY  - JOUR
AB  - **Innledning** 
Helsedirektoratet skal revidere &laquo;Nasjonal faglig retningslinje for gravide i legemiddelassistert rehabilitering (LAR)&raquo;. De bestilte i juni 2018 en systematisk oversikt fra Folkehelseinstituttet om effekter av bruk av buprenorfin sammenliknet med metadon på utfall hos kvinner som har vært i LAR gjennom hele eller deler av svangerskapet og på utfall hos foster og barn som prenatalt har vært eksponert for et av LAR-legemidlene. Legemiddelassistert rehabilitering (LAR) er et tiltak for personer med opiatavhengighetssyndrom (kode F11.2 i det internasjonale klassifiseringssystemet ICD-10) for å redusere bruk av illegale rusmidler og holde pasientene i rehabilitering lenger enn ved rehabilitering uten bruk av legemidler(1;2)(1;2)(1;2). De siste ti årene har antallet barn født av kvinner i LAR ifølge tall fra Medisinsk fødselsregister variert mellom 30 og 60 per år. I 2016 ble det født 32 barn av kvinner i LAR. De fleste kvinnene var allerede i LAR da de ble gravide. Den eksisterende nasjonale faglige retningslinjen for gravide i LAR anser, i likhet med internasjonale retningslinjer, buprenorfin og metadon for å være likeverdige legemidler. Den hyppigst rapporterte uønskete effekten ved mors behandling med buprenorfin og metadon hos barnet er neonatalt abstinenssyndrom (NAS). Rundt halvparten av nyfødte som har vært eksponert for buprenorfin eller metadon i fosterlivet får abstinenssymptomer når tilførselen av LAR-medikamentet brått stopper opp ved fødsel. Denne systematiske oversikten har som hensikt å sammenlikne effekter av buprenorfin med effekter av metadon på utfall hos kvinner som har vært i LAR gjennom hele eller deler av svangerskapet og på utfall hos foster og barn som prenatalt har vært eksponert for et av LAR-legemidlene. 

**Metode** 
En forskningsbibliotekar utviklet søkestrategien med innspill fra prosjektgruppen. En annen forskningsbibliotekar fagfellevurderte søkestrategien. Vi søkte systematisk i følgende databaser: MEDLINE (Ovid), Embase (Ovid), PsycINFO (Ovid) og CINAHL. Vi vurderte alle treffene i litteratursøket opp mot forhåndsbestemte inklusjonskriterier, først på grunnlag av titler og sammendrag, så på fulltekstnivå. Fra hver inkluderte studie hentet vi ut forhåndsbestemte data og vurderte risiko for skjevheter (metodisk kvalitet). Inklusjon, datauthenting og vurdering av risiko for skjevheter ble utført av to medarbeidere uavhengig av hverandre. Vi slo sammen effektestimater fra de inkluderte i metaanalyser der det var mulig, og to medarbeidere vurderte vår tillit til effektestimatene ved hjelp av Grading of Recommendations Assessment, Development and Evaluation (GRADE). 

**Resultater** 
Vi identifiserte 760 unike referanser i databasesøket. Av disse ble 106 vurdert som valgbare og lest i fulltekst, men ytterligere 42 referanser ble ekskludert. Vi inkluderte 38 studier fordelt på 64 publikasjoner: tre randomiserte kontrollerte studier (RCTer) (N=177) og 35 observasjonsstudier (N=1314). Ingen av studiene omfattet kvinner som var i LAR hele svangerskapet, som er det vanligste i Norge. Studiene inkluderte utfall hos kvinnene (røyking og rusmiddelbruk under svangerskapet), fosterutfall (fosterdød, dødfødsel, intrauterin veksthemning) og nyfødtutfall (forekomst av NAS, liten for gestasjonsalder og for tidlig fødte, behandlingsvarighet, vekt, lengde, hodeomkrets og gestasjonsalder). Tre av studiene rapporterte langtidsutfall. Studiene fant sted i Australia, USA, Frankrike, Storbritannia, Tsjekkia, Østerrike, Danmark, Sverige og Norge. Studiene omfattet mellom 18 og 129 kvinner i de randomiserte studiene gjennomført i perioden 2005-2006 og mellom 51 og 615 kvinner i observasjonsstudiene gjennomført i perioden 2008 og 2018. Vi har svært liten tillit til effektestimatene fra RCTene, som antydet at flere kvinner i buprenorfingruppen enn i metadongruppen brukte rusmidler under svangerskapet og opplevde fosterdød, mens færre nyfødte i buprenorfingruppen ble født for tidlig og fikk NAS-diagnose. Dette gjelder også effektestimatene fra RCTene som antydet at de nyfødte i buprenorfingruppen hadde høyere gestasjonsalder og større vekt, kroppslengde og hodeomkrets, og trengte kortere behandlingstid enn de nyfødte i metadongruppen. Det er altså usikkert hvor nære disse effektestimatene ligger de sanne effektene. Vi har også svært liten tillit til effektestimatene fra observasjonsstudiene, som antydet at færre kvinner i buprenorfingruppen enn i metadongruppen røkte og brukte rusmidler under svangerskapet. Det så ikke ut til å være noen forskjell mellom gruppene i fosterdød, dødfødsel og intrauterin veksthemming. Videre antydet effektestimatene fra observasjonsstudiene at nyfødtutfallene var noe bedre i buprenorfingruppen enn i metadongruppen. Det er altså usikkert hvor nære disse effektestimatene ligger de sanne effektene. 

**Diskusjon** 
Funnene i denne systematiske oversikten føyer seg til funn i andre oppsummeringer som sammenlikner buprenorfin og metadon hos gravide: i den grad det er forskjeller i behandlingseffekt, er de muligens til fordel for buprenorfingruppen, men studiene er for metodisk svake til å kunne konkludere sikkert om effektenes størrelse og retning. I de inkluderte studiene observasjonsstudiene var ofte kvinnene i buprenorfingruppen yngre og mindre belastet enn kvinnene i metadongruppen. En slik seleksjonsskjevhet kan ha påvirket retningen og størrelsen på effektestimatene. Denne typen skjevheter gjør det krevende å konkludere om hva slags effekt man kan forvente av å bruke buprenorfin versus metadon under svangerskapet. Det er uklart hvor sammenliknbar norsk LAR-praksis er med praksis i andre land, særlig når det gjelder hvor tett oppfølging kvinnene får både når det gjelder rusrelaterte spørsmål og svangerskapsomsorg. Et annet problem med generaliserbarheten, er at i Norge er de fleste kvinnene allerede i LAR før de blir gravide, mens de fleste deltakerne i de inkluderte studiene var gravide da de begynte i LAR, eller vi mangler informasjon om eksponeringstid. Sparsomme bakgrunnsopplysninger om deltakerne i studiene gjør det også vanskelig å vurdere overførbarheten til den norske populasjonen av gravide kvinner i LAR. Denne systematiske oversikten er basert på et nylig og grundig litteratursøk ved hjelp av en eksplisitt søkestrategi og parvise, uavhengige vurderinger av studienes valgbarhet. Det er lite sannsynlig at vi ikke har fanget opp relevante studier om effekt av buprenorfin sammenliknet med metadon under svangerskapet. Vi har vurdert den metodiske kvaliteten ved de inkluderte studiene og vår tillit til effektestimatene basert på GRADE. Videre har vi kvalitetssikret den systematiske oversikten ved å inkludere fagfellevurderinger fra eksterne og interne eksperter på LAR og gravide. Det er en styrke ved denne oversikten at våre inklusjonskriterier omfattet observasjonsstudier i tillegg til RCTer, som mange systematiske oversikter begrenser seg til for å svare på effektspørsmål. Likevel er det viktig å understreke begrensningene ved slike studiedesign. Små, metodisk svake observasjonsstudier gir en betydelig risiko for systematiske skjevheter i resultatene. Resultatenes betydning for praksis Resultatene i denne systematiske oversikten gir et uklart bilde av hva som er sannsynlige effekter av buprenorfin sammenliknet med metadon hos kvinner som blir gravide mens de er i LAR. Funnene fra denne systematiske oversikten må ses i en sammenheng med den erfaringsbaserte kunnskapen, brukerkunnskapen og konteksten før en beslutning om endring i retningslinjen tas. 

**Konklusjon** 
Det forskningsbaserte kunnskapsgrunnlaget er så usikkert at vi ikke kan svare på spørsmålet om det er noen forskjell i effekt på utfall hos kvinnen, fosteret eller barnet når vi sammenlikner bruk av buprenorfin med bruk av metadon hos gravide i LAR.
AU  - Kornør,
AU  - H.
AU  - Sandberg,
AU  - H.
AU  - Muller,
AU  - A.
AU  - E.
AU  - Thuve
AU  - Dahm,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/buprenorfin-sammenlignet-med-metadon-for-gravide-kvinner-i-legemiddelassistert-rehabilitering-rapport-2019%20(1).pdf
PY  - 2019
T2  - Folkehelseinstituttet
TI  - Buprenorfin sammenlignet med metadon for gravide kvinner i legemiddelassistert rehabilitering (LAR): systematisk oversikt
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
The physical and psychosocial benefits of physical activity for typically developing youth are well established; however, its impact on youth with intellectual disabilities is not as well understood. The aims of this review and meta-analysis were to synthesize the literature and quantify the effects of physical activity on the physical and psychosocial health of youth with intellectual disabilities.

**METHOD:**
Studies meeting the inclusion criteria were grouped by their focus on physical health and/or psychosocial health outcomes. Meta-analyses were performed using 3-level, random effects and mixed effects models.

**RESULTS:** 
One hundred nine studies met the inclusion criteria. Physical activity had a large effect on physical health (g = 0.773, P &lt; .001) and a moderately large effect (g = 0.682, P &lt; .001) on psychosocial health. Participant age, intellectual disability level, other developmental disabilities, outcome type, and intervention type moderated the effects of physical activity on physical health, whereas study design, risk of bias, other developmental disabilities, outcome type, and intervention type were moderators on psychosocial health.

**CONCLUSIONS:** 
Physical activity has positive effects on the physical and psychosocial health of youth with intellectual disabilities. Although resistance training shows the most physical benefits, teaching movement and sports skills appear to benefit their physical and psychosocial health.
AN  - 31586434
AU  - Kapsal,
AU  - N.
AU  - J.
AU  - Dicke,
AU  - T.
AU  - Morin,
AU  - A.
AU  - J.
AU  - S.
AU  - Vasconcellos,
AU  - D.
AU  - Maiano,
AU  - C.
AU  - Lee,
AU  - J.
AU  - Lonsdale,
AU  - C.
DA  - Oct 02
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1123/jpah.2018-0675
DP  - Ovid Technologies
J2  - J Phys Act Health
L1  - internal-pdf://2508154671/Kapsal-2019.pdf
LA  - English
M3  - Review
N1  - Kapsal, Nathanial JDicke, TheresaMorin, Alexandre J SVasconcellos, DiegoMaiano, ChristopheLee, JaneLonsdale, Chrisjpah.2018-0675
PY  - 2019
SP  - 1-9
T2  - Journal of Physical Activity &amp; Health
TI  - Effects of Physical Activity on the Physical and Psychosocial Health of Youth With Intellectual Disabilities: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31586434
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31586434&amp;id=doi:10.1123%2Fjpah.2018-0675&amp;issn=1543-3080&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-9&amp;date=2019&amp;title=Journal+of+Physical+Activity+%26+Health&amp;atitle=Effects+of+Physical+Activity+on+the+Physical+and+Psychosocial+Health+of+Youth+With+Intellectual+Disabilities%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Kapsal&amp;pid=%3Cauthor%3EKapsal+NJ%3C%2Fauthor%3E%3CAN%3E31586434%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.humankinetics.com/view/journals/jpah/aop/article-10.1123-jpah.2018-0675.xml
ER  -
TY  - JOUR
AB  - OBJECTIVE: 
To study the drop-out rates in trials of selective serotonin and serotonin-norepinephrine reuptake inhibitors (SSRIs and SNRIs).

METHODS: 
This study is a systematic review and meta-analysis of trials. The main outcome measure: Overall drop-out rate. Secondary outcomes were drop-outs due to adverse events and lack of effect. We obtained clinical study reports (CSRs) of five antidepressant drugs from the European Medicines Agency and the UK&#039;s Medicines and Healthcare products Regulatory Agency. The eligibility criteria for selecting studies: double-blind randomised, placebo-controlled trials for any indication.

DATA EXTRACTION AND ANALYSIS: 
The primary outcome was extracted by two researchers independently and meta-analysed using the Mantel-Haenszel method (fixed effect model). The secondary outcomes were extracted by one researcher and checked by another. Sensitivity analyses were performed using Peto&#039;s odds ratio and beta binomial methods, due to presence of null events, and by excluding unreliable trials.

RESULTS: 
We included 71 CSRs (67,319 pages) with information on 73 trials (11,057 patients on SSRI or SNRI drugs, and 7,369 on placebo). There were minor discrepancies within the CSRs when a modified intention to treat principle was used and patients lost to follow up early in the trial were not accounted for. Significantly more patients dropped out on active drug than on placebo, risk ratio 1.08 (95% CI 1.03 to 1.13), with no difference between adults and children/ adolescents, RR = 1.08 (1.03 to 1.13) and 1.07 (0.95 to 1.21), respectively. When three trials with a prior single-blind phase on active drug were removed, the difference was a risk ratio of 1.12 (1.07 to 1.18), whereas the result was the same after removal of three trials with fraudulent data or other issues with data validity, risk ratio 1.08 (1.03 to 1.13). There were more drop-outs due to adverse events on active drug than on placebo, risk ratio 2.63 (2.33 to 2.96). There were fewer drop-outs due to lack of effect, risk ratio 0.47 (0.43 to 0.53). However, this result is biased; when more people drop out due to adverse effects, fewer can drop out because of lack of effect.

CONCLUSIONS: 
By using CSRs, we were able to demonstrate for the first time that more patients dropped out on active drug than on placebo. As it can be argued that the drop-out rate reflects the patients&#039; overall assessment of the balance between benefits and harms, our review adds to the growing concern that SSRIs and SNRIs might not have the desired effect. Our review also highlights the importance of using CSRs for undertaking reviews of drugs.
AD  - Sharma, Tarang. Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark.Guski, Louise Schow. Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark.Freund, Nanna. Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark.Meng, Dina Muscat. Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark.Gotzsche, Peter C. Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark.Gotzsche, Peter C. Institute for Scientific Freedom, Copenhagen, Denmark.
AN  - 31561390
AU  - Sharma,
AU  - T.
AU  - Guski,
AU  - L.
AU  - S.
AU  - Freund,
AU  - N.
AU  - Meng,
AU  - D.
AU  - M.
AU  - Gotzsche,
AU  - P.
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3233/JRS-195041
DP  - Ovid Technologies
J2  - Int
KW  - *Antidepressive Agents/ae [Adverse Effects]
KW  - Antidepressive Agents/tu [Therapeutic Use]
KW  - Depressive Disorder/di [Diagnosis]
KW  - *Depressive Disorder/dt [Drug Therapy]
KW  - Double-Blind Method
KW  - *Drug-Related Side Effects and Adverse Reactions/ep [Epidemiology]
KW  - Female
KW  - Follow-Up Studies
KW  - Humans
KW  - Incidence
KW  - Male
KW  - *Patient Dropouts/sn [Statistics &amp; Numerical Data]
KW  - Randomized Controlled Trials as Topic
KW  - *Serotonin Uptake Inhibitors/ae [Adverse Effects]
KW  - Serotonin Uptake Inhibitors/tu [Therapeutic Use]
KW  - United Kingdom
KW  - 0 (Antidepressive Agents)
KW  - 0 (Serotonin Uptake Inhibitors)
L1  - internal-pdf://3732831368/Sharma_2019.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Sharma, TarangGuski, Louise SchowFreund, NannaMeng, Dina MuscatGotzsche, Peter C
PY  - 2019
SP  - 217-232
T2  - International Journal of Risk &amp; Safety in Medicine
TI  - Drop-out rates in placebo-controlled trials of antidepressant drugs: A systematic review and meta-analysis based on clinical study reports
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=31561390
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31561390&amp;id=doi:10.3233%2FJRS-195041&amp;issn=0924-6479&amp;isbn=&amp;volume=30&amp;issue=4&amp;spage=217&amp;pages=217-232&amp;date=2019&amp;title=International+Journal+of+Risk+%26+Safety+in+Medicine&amp;atitle=Drop-out+rates+in+placebo-controlled+trials+of+antidepressant+drugs%3A+A+systematic+review+and+meta-analysis+based+on+clinical+study+reports.&amp;aulast=Sharma&amp;pid=%3Cauthor%3ESharma+T%3C%2Fauthor%3E%3CAN%3E31561390%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 30
ER  -
TY  - JOUR
AB  - **Background:** 
Adolescence represents an unprecedented opportunity to invest in health. Individual adolescent life skills programs in low- and middle-income countries (LMICs) have demonstrated success but neither their relative effectiveness across multiple health arenas, including mental health, nor their key ingredients have been examined. 

**Method(s):** 
We conducted a systematic review and meta-analysis to identify key implementation processes and effectiveness of life skills programs among adolescents in LMICs which targeted at least one mental health outcome, as well as their relative effectiveness. Six academic databases, including PubMed and PsychInfo and bibliographies of related reviews, were systematically searched until July 1, 2016, with no restrictions on language or publication year. Studies were excluded if they were conducted in HIC settings, among chronically ill populations or lacking adolescents aged 10-19 years. Data from published reports related to the characteristics of RCTs and their implementation processes related to &#039;who, what, how and where&#039; were extracted, including the development of a taxonomy to determine which life skills constituted each program. Meta-analyses with random effects models examined the overall trial effectiveness, as determined by their primary outcomes. Subsequent exploratory analyses determined which implementation processes predicted trial effectiveness (PROSPERO CRD42016043448). 

**Result(s):** 
We included 50 eligible RCTs from 45 articles with a focus on an adolescent health program, which targeted at least one or more mental health outcomes. Most of the RCTs, conducted across 19 LMICs, targeted students (82%) and refugees (7%), and both genders (71%). Most of the interventions were delivered by teachers (n = 12), and specialist providers (n = 11), and most were focused on high-risk groups rather than clinically-disordered populations. These interventions were effective in reducing symptoms of anger (SMD = 1.234), improving life skills (SMD = 0.755) and functioning (SMD = 0.491), and decreasing PTSD (SMD = 0.327), depression and anxiety (SMD = 0.305). Trial effectiveness was positively associated with the following life skills: interventions focused on parent-child interactions (beta = 0.557, p &lt; 0.05), assessing interpersonal relations (beta = 0.204, p &lt; 0.05) and stress management (beta = 0.216, p &lt; 0.05). 

**Discussion(s):** 
Our results demonstrate the benefits of life skills programs targeting one or more mental health outcomes and co-occurring risk factors in school and community settings. Comprehensive programs focusing on multiple life skills related to the individual, his or her social environment and, in particular, interventions promoting parent-child interactions may hold particular promise in LMICs to address the burden of poor mental health and other health arenas. Copyright &copy; 2019 Elsevier Ltd
AN  - 2002021220
AU  - Singla,
AU  - D.
AU  - R.
AU  - Waqas,
AU  - A.
AU  - Hamdani,
AU  - S.
AU  - U.
AU  - Suleman,
AU  - N.
AU  - Zafar,
AU  - S.
AU  - W.
AU  - Zill
AU  - e,
AU  - Huma
AU  - Saeed,
AU  - K.
AU  - Servili,
AU  - C.
AU  - Rahman,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.brat.2019.04.010
L1  - internal-pdf://4147881543/Singla-2019-Implementation and effectiveness o.pdf
PY  - 2019
T2  - Behaviour Research and Therapy
TI  - Implementation and effectiveness of adolescent life skills programs in low- and middle-income countries: A critical review and meta-analysis
UR  - http://www.elsevier.com/locate/brat
UR  - https://pdf.sciencedirectassets.com/271799/AIP/1-s2.0-S0005796719300749/main.pdf?X-Amz-Security-Token=AgoJb3JpZ2luX2VjECcaCXVzLWVhc3QtMSJIMEYCIQClIKdInhTEIiwW1VN1ulUWcalTrXoOg0xbAEsM8e7SkgIhAPhv0wDBlRgEkgsxDqg1LD5MX4z8SwY92DZhxY%2BVoKoQKuMDCKD%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEQAhoMMDU5MDAzNTQ2ODY1IgxNl2ipa%2BNxhB7AtnYqtwO4PLsIoJx9fb0ydrgcVMFxgHmv2WoSd8egVF%2FAbjuUK%2BQCj4o4%2FRHRyhschMEehU8AU0MI3elYNd70G0nayBpLYy6j3mv23xJTVfmuwO2TDZI1rAmmQ1FTWd89iRS5YlbpGqKZMfj5UPHo09mdCJTxngL5jTB9NdGmhdzmaoXP1JyojVX%2BnoMBi%2FAbwB1jDWXontQLHXdBOQ5FaXkla5LKg%2B6jqml7V%2BqBywS9PC%2F7QUAtpRG0rVqRiC7dtKsvKWFZDVL5OJIz1%2Bct68ScgkCZ2fhJsfmAz0H6QniDQN0r2824SJXETyQ8eG3soWttueKgHmhLizsk%2F4Vmm%2BIxGu7vjg59%2F%2FeWRhIHAousr%2FVx2DYc%2BuD4jaoOsFtr60gt2UwI7iPECUOT7HFu9CLWEzLIB71n2NwNZoWKUgchQJ%2BvTSjOvdIuG4Xc2TK7elnBsuR1eoNauOOCY7A4EWHt8JTN3NLGGFoMSulULPi2JmRw%2BTVJT4%2FdmLhm74IpvTfQTSt4wvrWcqdOXAbmGdGdsLWhPOLbkzeRYFPVVucQo3HDBvSgcUb%2BpVP8S7N9VEeq5DhltoMmvGUvMOHphOoFOrMBZ5KHD7V%2F2SljsFfWpLYh1DKypVdMRh2oXHMMtHqk6%2FGHzYUniklJa31A6l%2FXamIqV51cL6%2BK1399Odqs9v6ovvyHdJFizCLbx4VlJ44MQuFzR1tpdWPdSgS%2Fyka4H5rfSeRK7QL%2BylDsEBnj8ekHoF87KWZqBHkl8e13RCzQSlEKtPSAe%2F42EhxTxhCbGVOWhFKOlfHXVBQ6pTAM7ZlU5T6k%2FI0YHk2HyFovKuCUr%2BjQ%2Fd4%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20190731T080004Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYQQK2QHTZ%2F20190731%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=8462f83282df3286911c1566a835719ba503e7e651aa21d392ffff2c9cacfbd2&amp;hash=7d546a52b9023dfa7a7a90325bbeeb226e47976f527aa0cc8f4bc0e23eb91b8e&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0005796719300749&amp;tid=spdf-b0ba5e3f-a367-4b07-8d70-65618504a8b8&amp;sid=5239e28b53c4514899390fe5a74f9e378139gxrqb&amp;type=client
VL  - (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Evidence suggests that participation in physical activity may support young people&#039;s current and future mental health. Although previous reviews have examined the relationship between physical activity and a range of mental health outcomes in children and adolescents, due to the large increase in published studies there is a need for an update and quantitative synthesis of effects. 

**OBJECTIVES: **
The objectives of this study were to determine the effect of physical activity interventions on mental health outcomes by conducting a systematic review and meta-analysis, and to systematically synthesize the observational evidence (both longitudinal and cross-sectional studies) regarding the associations between physical activity and sedentary behavior and mental health in preschoolers (2-5 years of age), children (6-11 years of age) and adolescents (12-18 years of age). 

**METHODS:**
A systematic search of the PubMed and Web of Science electronic databases was performed from January 2013 to April 2018, by two independent researchers. Meta-analyses were performed to examine the effect of physical activity on mental health outcomes in randomized controlled trials (RCTs) and non-RCTs (i.e. quasi-experimental studies). A narrative synthesis of observational studies was conducted. Studies were included if they included physical activity or sedentary behavior data and at least one psychological ill-being (i.e. depression, anxiety, stress or negative affect) or psychological well-being (i.e. self-esteem, self-concept, self-efficacy, self-image, positive affect, optimism, happiness and satisfaction with life) outcome in preschoolers, children or adolescents. 

**RESULTS: **
A total of 114 original articles met all the eligibility criteria and were included in the review (4 RCTs, 14 non-RCTs, 28 prospective longitudinal studies and 68 cross-sectional studies). Of the 18 intervention studies, 12 (3 RCTs and 9 non-RCTs) were included in the meta-analysis. There was a small but significant overall effect of physical activity on mental health in children and adolescents aged 6-18 years (effect size 0.173, 95% confidence interval 0.106-0.239, p &lt; 0.001, percentage of total variability attributed to between-study heterogeneity [I&lt;sup&gt;2&lt;/sup&gt;] = 11.3%). When the analyses were performed separately for children and adolescents, the results were significant for adolescents but not for children. Longitudinal and cross-sectional studies demonstrated significant associations between physical activity and lower levels of psychological ill-being (i.e. depression, stress, negative affect, and total psychological distress) and greater psychological well-being (i.e. self-image, satisfaction with life and happiness, and psychological well-being). Furthermore, significant associations were found between greater amounts of sedentary behavior and both increased psychological ill-being (i.e. depression) and lower psychological well-being (i.e. satisfaction with life and happiness) in children and adolescents. Evidence on preschoolers was nearly non-existent. 

**CONCLUSIONS: **
Findings from the meta-analysis suggest that physical activity interventions can improve adolescents&#039; mental health, but additional studies are needed to confirm the effects of physical activity on children&#039;s mental health. Findings from observational studies suggest that promoting physical activity and decreasing sedentary behavior might protect mental health in children and adolescents. 

**PROSPERO Registration Number: **
CRD42017060373.
AN  - 30993594
AU  - Rodriguez-Ayllon,
AU  - M.
AU  - Cadenas-Sanchez,
AU  - C.
AU  - Estevez-Lopez,
AU  - F.
AU  - Munoz,
AU  - N.
AU  - E.
AU  - Mora-Gonzalez,
AU  - J.
AU  - Migueles,
AU  - J.
AU  - H.
AU  - Molina-Garcia,
AU  - P.
AU  - Henriksson,
AU  - H.
AU  - Mena-Molina,
AU  - A.
AU  - Martinez-Vizcaino,
AU  - V.
AU  - Catena,
AU  - A.
AU  - Lof,
AU  - M.
AU  - Erickson,
AU  - K.
AU  - I.
AU  - Lubans,
AU  - D.
AU  - R.
AU  - Ortega,
AU  - F.
AU  - B.
AU  - Esteban-Cornejo,
AU  - I.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s40279-019-01099-5
L1  - internal-pdf://4208521696/Rodriguez-Ayllo-2019-Role of Physical Activity.pdf
PY  - 2019
SP  - 16
T2  - Sports Medicine
TI  - Role of Physical Activity and Sedentary Behavior in the Mental Health of Preschoolers, Children and Adolescents: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30993594
UR  - https://link.springer.com/article/10.1007%2Fs40279-019-01099-5
VL  - 16
ER  -
TY  - JOUR
AB  - **CONTEXT:** 
Although adolescent mental health interventions are widely implemented, little consensus exists about elements comprising successful models. 

**OBJECTIVE:** 
We aimed to identify effective program components of interventions to promote mental health and prevent mental disorders and risk behaviors during adolescence and to match these components across these key health outcomes to inform future multicomponent intervention development. 

**DATA SOURCES:** 
A total of 14 600 records were identified, and 158 studies were included. 

**STUDY SELECTION:** 
Studies included universally delivered psychosocial interventions administered to adolescents ages 10 to 19. We included studies published between 2000 and 2018, using PubMed, Medline, PsycINFO, Scopus, Embase, and Applied Social Sciences Index Abstracts databases. We included randomized controlled, cluster randomized controlled, factorial, and crossover trials. Outcomes included positive mental health, depressive and anxious symptomatology, violence perpetration and bullying, and alcohol and other substance use. 

**DATA EXTRACTION:** 
Data were extracted by 3 researchers who identified core components and relevant outcomes. Interventions were separated by modality; data were analyzed by using a robust variance estimation meta-analysis model, and we estimated a series of single-predictor meta-regression models using random effects. 

**RESULTS:** 
Universally delivered interventions can improve adolescent mental health and reduce risk behavior. Of 7 components with consistent signals of effectiveness, 3 had significant effects over multiple outcomes (interpersonal skills, emotional regulation, and alcohol and drug education). LIMITATIONS: Most included studies were from high-income settings, limiting the applicability of these findings to low- and middle-income countries. Our sample included only trials. 

**CONCLUSIONS:** 
Three program components emerged as consistently effective across different outcomes, providing a basis for developing future multioutcome intervention programs.
AN  - 31262779
AU  - Skeen,
AU  - S.
AU  - Laurenzi,
AU  - C.
AU  - A.
AU  - Gordon,
AU  - S.
AU  - L.
AU  - du
AU  - Toit,
AU  - S.
AU  - Tomlinson,
AU  - M.
AU  - Dua,
AU  - T.
AU  - Fleischmann,
AU  - A.
AU  - Kohl,
AU  - K.
AU  - Ross,
AU  - D.
AU  - Servili,
AU  - C.
AU  - Brand,
AU  - A.
AU  - S.
AU  - Dowdall,
AU  - N.
AU  - Lund,
AU  - C.
AU  - van
AU  - der
AU  - Westhuizen,
AU  - C.
AU  - Carvajal-Aguirre,
AU  - L.
AU  - Eriksson
AU  - de
AU  - Carvalho,
AU  - C.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1542/peds.2018-3488
L1  - internal-pdf://4040814005/Skeen-2019-Adolescent Mental Health Program Co.pdf
PY  - 2019
T2  - Pediatrics
TI  - Adolescent Mental Health Program Components and Behavior Risk Reduction: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31262779
UR  - https://pediatrics.aappublications.org/content/144/2/e20183488
VL  - 01
ER  -
TY  - JOUR
AB  - Students with autism spectrum disorder (ASD) are increasingly educated alongside typically developing peers in regular education environments. These students have impairments that may hinder their success in inclusive school settings and require individualized supports to improve outcomes. 

The purpose of this meta-analysis and best-evidence synthesis is to examine the characteristics of interventions for students with ASD in inclusive settings, offer quantitative analysis of intervention effects, examine potential moderating variables that influence outcomes, analyze the social validity of these interventions, and provide recommendations for practice and future research. 

The 28 included studies met the What Works Clearinghouse standards for group design and single-case design research. Studies focused mostly on social communication skills, produced moderate to large effects, and were generally found to be socially valid. Function-based interventions, visual supports, self-monitoring strategies, and peer-mediated interventions resulted in mostly large effects, and teacher delivered interventions produced the largest overall effects. 

More high-quality studies for students with ASD in inclusive school settings are needed to advance evidence-based practice for this population. 

(PsycINFO Database Record (c) 2019 APA, all rights reserved).
AN  - 30869925
AU  - Watkins,
AU  - L.
AU  - Ledbetter-Cho,
AU  - K.
AU  - O&#039;Reilly,
AU  - M.
AU  - Barnard-Brak,
AU  - L.
AU  - Garcia-Grau,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/bul0000190
L1  - internal-pdf://0330878647/Watkins-2019-Interventions for students with a.pdf
PY  - 2019
SP  - 14
T2  - Psychological Bulletin
TI  - Interventions for students with autism in inclusive settings: A best-evidence synthesis and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30869925
VL  - 14
ER  -
TY  - JOUR
AB  - **Background**
Children who are securely attached to at least one parent are able to be comforted by that parent when they are distressed and explore the world confidently by using that parent as a &#039;secure base&#039;. Research suggests that a secure attachment enables children to function better across all aspects of their development. Promoting secure attachment, therefore, is a goal of many early interventions. Attachment is mediated through parental sensitivity to signals of distress from the child. One means of improving parental sensitivity is through video feedback, which involves showing a parent brief moments of their interaction with their child, to strengthen their sensitivity and responsiveness to their child&#039;s signals.

**Objectives**
To assess the effects of video feedback on parental sensitivity and attachment security in children aged under five years who are at risk for poor attachment outcomes.

**Search methods**
In November 2018 we searched CENTRAL, MEDLINE, Embase, CINAHL, PsycINFO, nine other databases and two trials registers. We also handsearched the reference lists of included studies, relevant systematic reviews, and several relevant websites.

**Selection criteria**
Randomised controlled trials (RCTs) and quasi‐RCTs that assessed the effects of video feedback versus no treatment, inactive alternative intervention, or treatment as usual for parental sensitivity, parental reflective functioning, attachment security and adverse effects in children aged from birth to four years 11 months.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane.Main resultsThis review includes 22 studies from seven countries in Europe and two countries in North America, with a total of 1889 randomised parent‐child dyads or family units. Interventions targeted parents of children aged under five years, experiencing a wide range of difficulties (such as deafness or prematurity), or facing challenges that put them at risk of attachment issues (for example, parental depression). Nearly all studies reported some form of external funding, from a charitable organisation (n = 7) or public body, or both (n = 18). We considered most studies as being at low or unclear risk of bias across the majority of domains, with the exception of blinding of participants and personnel, where we assessed all studies as being at high risk of performance bias. For outcomes where self‐report measures were used, such as parental stress and anxiety, we rated all studies at high risk of bias for blinding of outcome assessors.

Parental sensitivity: A meta‐analysis of 20 studies (1757 parent‐child dyads) reported evidence of that video feedback improved parental sensitivity compared with a control or no intervention from postintervention to six months&#039; follow‐up (standardised mean difference (SMD) 0.34, 95% confidence interval (CI) 0.20 to 0.49, moderate‐certainty evidence). The size of the observed impact compares favourably to other, similar interventions.

Parental reflective functioning: No studies reported this outcome.

Attachment security: A meta‐analysis of two studies (166 parent‐child dyads) indicated that video feedback increased the odds of being securely attached, measured using the Strange Situation Procedure, at postintervention (odds ratio 3.04, 95% CI 1.39 to 6.67, very low‐certainty evidence). A second meta‐analysis of two studies (131 parent‐child dyads) that assessed attachment security using a different measure (Attachment Q‐sort) found no effect of video feedback compared with the comparator groups (SMD 0.02, 95% CI &minus;0.33 to 0.38, very low‐certainty evidence).

Adverse events: Eight studies (537 parent‐child dyads) contributed data at postintervention or short‐term follow‐up to a meta‐analysis of parental stress, and two studies (311 parent‐child dyads) contributed short‐term follow‐up data to a meta‐analysis of parental anxiety. There was no difference between intervention and comparator groups for either outcome. For parental stress the SMD between video feedback and control was &minus;0.09 (95% CI &minus;0.26 to 0.09, low‐certainty evidence), while for parental anxiety the SMD was &minus;0.28 (95% CI &minus;0.87 to 0.31, very low‐certainty evidence).

Child behaviour: A meta‐analysis of two studies (119 parent‐child dyads) at long‐term follow‐up found no evidence of the effectiveness of video feedback on child behaviour (SMD 0.04, 95% CI &minus;0.33 to 0.42, very low‐certainty evidence).

A moderator analysis found no evidence of an effect for the three prespecified variables (intervention type, number of feedback sessions and participating carer) when jointly tested. However, parent gender (both parents versus only mothers or only fathers) potentially has a statistically significant negative moderation effect, though only at &alpha; (alpha) = 0.1

**Authors&#039; conclusions**
There is moderate‐certainty evidence that video feedback may improve sensitivity in parents of children who are at risk for poor attachment outcomes due to a range of difficulties. There is currently only little, very low‐certainty evidence regarding the impact of video feedback on attachment security, compared with control: results differed based on the type of measure used, and follow‐up was limited in duration. There is no evidence that video feedback has an impact on parental stress or anxiety (low‐ and very low‐certainty evidence, respectively). Further evidence is needed regarding the longer‐term impact of video feedback on attachment and more distal outcomes such as children&#039;s behaviour (very low‐certainty evidence). Further research is needed on the impact of video‐feedback on paternal sensitivity and parental reflective functioning, as no study measured these outcomes. This review is limited by the fact that the majority of included parents were mothers.
AU  - O&#039;Hara,
AU  - L.
AU  - Smith,
AU  - E.
AU  - R.
AU  - Barlow,
AU  - J.
AU  - Livingstone,
AU  - N.
AU  - INS
AU  - Herath,
AU  - H.
AU  - Wei,
AU  - Y.
AU  - Frerich
AU  - Spreckelsen,
AU  - T.
AU  - Macdonald,
AU  - G.
DA  - 29. Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.CD012348.pub2
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Video feedback for parental sensitivity and attachment security in children under five years
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Youth depression is a debilitating condition that constitutes a major public health concern. A 2006 meta-analysis found modest benefits for psychotherapy vs. control. Has 13 more years of research improved that picture? We sought to find out. 

**METHOD: **
We searched PubMed, PsychINFO, and Dissertation Abstracts International for 1960-2017, identifying 655 randomized, English-language psychotherapy trials for ages 4-18 years. Of these, 55 assessed psychotherapy versus control for youth depression with outcome measures administered to both treatment and control conditions at post (k=53) and/or follow-up (k=32). Twelve study and outcome characteristics were extracted, and effect sizes were calculated for all psychotherapy vs. control comparisons. Using a three-level random-effects model, we obtained an overall estimate of the psychotherapy vs. control difference while accounting for the dependency among effect sizes. We then fitted a three-level mixed-effects model to identify moderators that might explain variation in effect size within and between studies. 

**RESULTS:**
Overall effect size (g) was 0.36 at posttreatment, 0.21 at follow-up (averaging 42 weeks after post-treatment). Three moderator effects were identified: effects were significantly larger for Interpersonal Therapy than CBT, for youth self-reported outcomes than parent-reports, and for comparisons with inactive control conditions (e.g., waitlist) than active controls (e.g., usual care). Effects showed specificity, with significantly smaller effects for anxiety and externalizing behavior outcomes than for depression measures. 

**CONCLUSION: **
Youth depression psychotherapy effects are modest, with no significant change over the past 13 years. The findings highlight the need for treatment development and research to improve both immediate and longer-term benefits.
AN  - 31004739
AU  - Eckshtain,
AU  - D.
AU  - Kuppens,
AU  - S.
AU  - Ugueto,
AU  - A.
AU  - Ng,
AU  - M.
AU  - Y.
AU  - Vaughn-Coaxum,
AU  - R.
AU  - Corteselli,
AU  - K.
AU  - Weisz,
AU  - J.
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2019.04.002
L1  - internal-pdf://3677481909/Eckshtain-2019-Meta-Analysis_ 13-Year Follow-U.pdf
PY  - 2019
SP  - 17
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Meta-Analysis: 13-Year Follow-Up of Psychotherapy Effects on Youth Depression
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31004739
UR  - https://www.sciencedirect.com/science/article/pii/S0890856719302655?via%3Dihub
VL  - 17
ER  -
TY  - JOUR
AB  - **Background**
Preterm infants may accumulate nutrient deficits leading to extrauterine growth restriction. Feeding preterm infants with nutrient‐enriched rather than standard formula might increase nutrient accretion and growth rates and might improve neurodevelopmental outcomes.

**Objectives**
To compare the effects of feeding with nutrient‐enriched formula versus standard formula on growth and development of preterm infants.

**Search methods**
We used the Cochrane Neonatal standard search strategy. This included electronic searches of the Cochrane Central Register of Controlled Trials (CENTRAL; 2018, Issue 11), MEDLINE, Embase, and the Cumulative Index to Nursing and Allied Health Literature (until November 2018), as well as conference proceedings, previous reviews, and clinical trials databases.

**Selection criteria**
Randomised and quasi‐randomised controlled trials that compared feeding preterm infants with nutrient‐enriched formula (protein and energy plus minerals, vitamins, or other nutrients) versus standard formula.

**Data collection and analysis**
We extracted data using the Cochrane Neonatal standard methods. Two review authors separately evaluated trial quality and extracted and synthesised data using risk ratios (RRs), risk differences, and mean differences (MDs). We assessed certainty of evidence at the outcome level using Grading of Recommendations Assessment, Development and Evaluation (GRADE) methods.

**Main results**
We identified seven trials in which a total of 590 preterm infants participated. Most participants were clinically stable preterm infants of birth weight less than 1850 g. Few participants were extremely preterm, extremely low birth weight, or growth restricted at birth. Trials were conducted more than 30 years ago, were formula industry funded, and were small with methodological weaknesses (including lack of masking) that might bias effect estimates. Meta‐analyses of in‐hospital growth parameters were limited by statistical heterogeneity. There is no evidence of an effect on time to regain birth weight (MD ‐1.48 days, 95% confidence interval (CI) ‐4.73 to 1.77) and low‐certainty evidence suggests that feeding with nutrient‐enriched formula increases in‐hospital rates of weight gain (MD 2.43 g/kg/d, 95% CI 1.60 to 3.26) and head circumference growth (MD 1.04 mm/week, 95% CI 0.18 to 1.89). Meta‐analysis did not show an effect on the average rate of length gain (MD 0.22 mm/week, 95% CI ‐0.70 to 1.13). Fewer data are available for growth and developmental outcomes assessed beyond infancy, and these do not show consistent effects of nutrient‐enriched formula feeding. Data from two trials did not show an effect on Bayley Mental Development Index scores at 18 months post term (MD 2.87, 95% CI ‐1.38 to 7.12; moderate‐certainty evidence). Infants who received nutrient‐enriched formula had higher Bayley Psychomotor Development Index scores at 18 months post term (MD 6.56. 95% CI 2.87 to 10.26; low‐certainty evidence), but no evidence suggested an effect on cerebral palsy (typical RR 0.79, 95% CI 0.30 to 2.07; 2 studies, 377 infants). Available data did not indicate any other benefits or harms and provided low‐certainty evidence about the effect of nutrient‐enriched formula feeding on the risk of necrotising enterocolitis in preterm infants (typical RR 0.72, 95% CI 0.41 to 1.25; 3 studies, 489 infants).

**Authors&#039; conclusions**
Available trial data show that feeding preterm infants nutrient‐enriched (compared with standard) formulas has only modest effects on growth rates during their initial hospital admission. No evidence suggests effects on long‐term growth or development. The GRADE assessment indicates that the certainty of this evidence is low, and that these findings should be interpreted and applied with caution. Further randomised trials would be needed to resolve this uncertainty.
AU  - Walsh,
AU  - V.
AU  - Brown,
AU  - J.
AU  - V.
AU  - E.
AU  - Askie,
AU  - L.
AU  - M.
AU  - Embleton,
AU  - N.
AU  - D.
AU  - McGuire,
AU  - W.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD004204.pub3
L1  - internal-pdf://1674431203/Walsh-2019-Nutrient‐enriched formula versus st.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Nutrient‐enriched formula versus standard formula for preterm infants
ER  -
TY  - JOUR
AB  - Background
Anorexia nervosa (AN) is characterised by a failure to maintain a normal body weight due to a paucity of nutrition, an intense fear of gaining weight or behaviour that prevents the individual from gaining weight, or both. The long‐term prognosis is often poor, with severe developmental, medical and psychosocial complications, high rates of relapse and mortality. &#039;Family therapy approaches&#039; indicate a range of approaches, derived from different theories, that involve the family in treatment. We have included therapies developed on the basis of dominant family systems theories, approaches that are based on or broadly similar to the family‐based therapy derived from the Maudsley model, approaches that incorporate a focus on cognitive restructuring, as well as approaches that involve the family without articulation of a theoretical approach.This is an update of a Cochrane Review first published in 2010.

Objectives
To evaluate the efficacy of family therapy approaches compared with standard treatment and other treatments for AN.

Search methods
We searched the Cochrane Common Mental Disorders Controlled Trials Register (CCMDCTR) and PsycINFO (OVID) (all years to April 2016). We ran additional searches directly on Cochrane Central Register for Controlled Trials (CENTRAL), MEDLINE, Ovid Embase, and PsycINFO (to 2008 and 2016 to 2018). We searched the World Health Organization (WHO) trials portal (ICTRP) and ClinicalTrials.gov, together with four theses databases (all years to 2018). We checked the reference lists of all included studies and relevant systematic reviews. We have included in the analyses only studies from searches conducted to April 2016.

Selection criteria
Randomised controlled trials (RCTs) of family therapy approaches compared to any other intervention or other types of family therapy approaches were eligible for inclusion. 

We included participants of any age or gender with a primary clinical diagnosis of anorexia nervosa.

Data collection and analysis
Four review authors selected the studies, assessed quality and extracted data. We used a random‐effects meta‐analysis. We used the risk ratio (with a 95% confidence interval) to summarise dichotomous outcomes and both the standardised mean difference and the mean difference to summarise continuous measures.

Main results
We included 25 trials in this version of the review (13 from the original 2010 review and 12 newly‐included studies). Sixteen trials were of adolescents, eight trials of adults (seven of these in young adults aged up to 26 years) and one trial included three age groups: one adolescent, one young adult and one adult. Most investigated family‐based therapy or variants. Reporting of trial conduct was generally inadequate, so that in a large number of studies we rated the risk of bias as unclear for many of the domains. Selective reporting bias was particularly problematic, with 68% of studies rated at high risk of bias in this area, followed by incomplete outcome data, with 44% of studies rated at high risk of bias in this area. For the main outcome measure of remission there was some low‐quality evidence (from only two studies, 81 participants) suggesting that family therapy approaches might offer some advantage over treatment as usual on rates of remission, post intervention (risk ratio (RR) 3.50, 95% confidence interval (CI) 1.49 to 8.23; I2 = 0%). However, at follow‐up, low‐quality evidence from only one study suggested this effect was not maintained. There was very low‐quality evidence from only one trial, which means it is difficult to determine whether family therapy approaches offer any advantage over educational interventions for remission (RR 9.00, 95% CI 0.53 to 153.79; 1 study, N = 30). Similarly, there was very low‐quality evidence from only five trials for remission post‐intervention, again meaning that it is difficult to determine whether there is any advantage of family therapy approaches over psychological interventions (RR 1.22, 95% CI 0.89 to 1.67; participants = 252; studies = 5; I2 = 37%) and at long‐term follow‐up (RR 1.08, 95% CI 0.91 to 1.28; participants = 200; studies = 4 with 1 of these contributing 3 pairwise comparisons for different age groups; I2 = 0%). There was no indication that the age group had any impact on the overall treatment effect; however, it should be noted that there were very few trials undertaken in adults, with the age range of adult studies included in this analysis from 20 to 27. There was some evidence of a small effect favouring family based therapy compared with other psychological interventions in terms of weight gain post‐intervention (standardised mean difference (SMD) 0.32, 95% CI 0.01 to 0.63; participants = 210; studies = 4 with 1 of these contributing 3 pairwise comparisons for different age groups; I2 = 11%) . Overall, there was insufficient evidence to determine whether there were any differences between groups across all comparisons for most of the secondary outcomes (weight, eating disorder psychopathology, dropouts, relapse, or family functioning measures), either at post‐intervention or at follow‐up.

Authors&#039; conclusions
There is a limited amount of low‐quality evidence to suggest that family therapy approaches may be effective compared to treatment as usual in the short term. This finding is based on two trials that included only a small number of participants, and both had issues about potential bias. There is insufficient evidence to determine whether there is an advantage of family therapy approaches in people of any age compared to educational interventions (one study, very low quality) or other psychological therapies (five studies, very low quality). Most studies contributing to this finding were undertaken in adolescents and youth. There are clear potential impacts on how family therapy approaches might be delivered to different age groups and further work is required to understand what the resulting effects on treatment efficacy might be. There is insufficient evidence to determine whether one type of family therapy approach is more effective than another. The field would benefit from further large, well‐conducted trials.
AU  - Fisher,
AU  - C.
AU  - A.
AU  - Skocic,
AU  - S.
AU  - Rutherford,
AU  - K.
AU  - A.
AU  - Hetrick,
AU  - S.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /cdsr/doi/10.1002/14651858.CD004780.pub3/full
L1  - internal-pdf://0443518010/Fisher-2018-Family therapy approaches for anor.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Family therapy approaches for anorexia nervosa (Update)
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Post-traumatic stress disorder (PTSD) is a potentially chronic and disabling disorder that affects a significant minority of youth exposed to trauma. Previous studies have concluded that trauma-focused cognitive behavioural therapy (TF-CBT) is an effective treatment for PTSD in youth, but the relative strengths of different psychological therapies are poorly understood.

**METHODS:** 
We undertook a systematic review and network meta-analyses of psychological and psychosocial interventions for children and young people with PTSD. Outcomes included PTSD symptom change scores post-treatment and at 1-4-month follow-up, and remission post-treatment.

**RESULTS:** 
We included 32 trials of 17 interventions and 2,260 participants. Overall, the evidence was of moderate-to-low quality. No inconsistency was detected between direct and indirect evidence. Individual forms of TF-CBT showed consistently large effects in reducing PTSD symptoms post-treatment compared with waitlist. The order of interventions by descending magnitude of effect versus waitlist was as follows: cognitive therapy for PTSD (SMD -2.94, 95%CrI -3.94 to -1.95), combined somatic/cognitive therapies, child-parent psychotherapy, combined TF-CBT/parent training, meditation, narrative exposure, exposure/prolonged exposure, play therapy, Cohen TF-CBT/cognitive processing therapy (CPT), eye movement desensitisation and reprocessing (EMDR), parent training, group TF-CBT, supportive counselling and family therapy (SMD -0.37, 95%CrI -1.60 to 0.84). Results for parent training, supportive counselling and family therapy were inconclusive. Cohen TF-CBT/CPT, group TF-CBT and supportive counselling had the largest evidence base. Results regarding changes in PTSD symptoms at follow-up and remission post-treatment were uncertain due to limited evidence.

**CONCLUSIONS:** 
Trauma-focused cognitive behavioural therapy, in particular individual forms, appears to be most effective in the management of PTSD in youth. EMDR is effective but to a lesser extent. Supportive counselling does not appear to be effective. Results suggest a large positive effect for emotional freedom technique, child-parent psychotherapy, combined TF-CBT/parent training, and meditation, but further research is needed to confirm these findings as they were based on very limited evidence.
AD  - Mavranezouli, Ifigeneia. Centre for Outcomes Research and Effectiveness, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.Mavranezouli, Ifigeneia. National Guideline Alliance, Royal College of Obstetricians and Gynaecologists, London, UK.Megnin-Viggars, Odette. Centre for Outcomes Research and Effectiveness, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.Megnin-Viggars, Odette. National Guideline Alliance, Royal College of Obstetricians and Gynaecologists, London, UK.Daly, Caitlin. Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.Dias, Sofia. Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.Stockton, Sarah. National Guideline Alliance, Royal College of Obstetricians and Gynaecologists, London, UK.Meiser-Stedman, Richard. Department of Clinical Psychology, Norwich Medical School, University of East Anglia, Norwich, UK.Trickey, David. The Anna Freud Centre, The Kantor Centre of Excellence, London, UK.Pilling, Stephen. Centre for Outcomes Research and Effectiveness, Research Department of Clinical, Educational and Health Psychology, University College London, London, UK.Pilling, Stephen. National Guideline Alliance, Royal College of Obstetricians and Gynaecologists, London, UK.
AN  - 31313834
AU  - Mavranezouli,
AU  - I.
AU  - Megnin-Viggars,
AU  - O.
AU  - Daly,
AU  - C.
AU  - Dias,
AU  - S.
AU  - Stockton,
AU  - S.
AU  - Meiser-Stedman,
AU  - R.
AU  - Trickey,
AU  - D.
AU  - Pilling,
AU  - S.
DA  - Jul 17
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.13094
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
L1  - internal-pdf://1539068319/Mavranezouli_et_al-2020-Journal_of_Child_Psych.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingJulMavranezouli, IfigeneiaMegnin-Viggars, OdetteDaly, CaitlinDias, SofiaStockton, SarahMeiser-Stedman, RichardTrickey, DavidPilling, Stephen
PY  - 2019
SP  - 17
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Research Review: Psychological and psychosocial treatments for children and young people with post-traumatic stress disorder: a network meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31313834
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31313834&amp;id=doi:10.1111%2Fjcpp.13094&amp;issn=0021-9630&amp;isbn=&amp;volume=&amp;issue=&amp;spage=jcpp&amp;pages=&amp;date=2019&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Research+Review%3A+Psychological+and+psychosocial+treatments+for+children+and+young+people+with+post-traumatic+stress+disorder%3A+a+network+meta-analysis.&amp;aulast=Mavranezouli&amp;pid=%3Cauthor%3EMavranezouli+I%3C%2Fauthor%3E%3CAN%3E31313834%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/jcpp.13094
VL  - 17
ER  -
TY  - JOUR
AB  - The systematic review and meta-analysis were conducted to analyze the psychological effects of exergames for children and adolescents with overweight or obesity. In August 2018, the electronic databases searched were PubMed, Scopus, Web of Science, SPORTDiscus, Science Direct, CINAHL, and PsycINFO. The eligibility criteria were defined according to the population, intervention, comparison, outcome, and study design. In relation to the population, only studies with children or adolescents with overweight or obesity and without any other comorbidities were analyzed. Only publications in English were considered. Nine studies were selected. The comparisons identified were in relation to weight, type of activity, and play style versus control and preintervention. The magnitude of effect size suggests that the practice of exergaming has a small effect on psychological outcomes. Furthermore, cooperative games produced greater attraction to the game (g = 4.71, 95% confidence interval [CI] = 3.23-6.19) and greater intrinsic motivation (g = 5.29; 95% CI = 3.68-6.90). It was verified that self-esteem (standard mean difference [SMD] = 0.37; 95% CI = 0.09-0.66), and self-efficacy (SMD = 0.42; 95% CI = 0.06-0.79) improved after playing an exergame. This systematic review and meta-analysis suggest that exergames may be effective in improving psychological aspects of children and adolescents with overweight or obesity. Given the limited number of studies, it is essential to increase scientific research in this area.
AD  - Andrade, Alexandro. Laboratory of Psychology of Sport and Exercise, Department of Physical Education, Center of Health Sciences and Sports, Santa Catarina State University, Florianopolis, Brazil.Correia, Clara Knierim. Laboratory of Psychology of Sport and Exercise, Department of Physical Education, Center of Health Sciences and Sports, Santa Catarina State University, Florianopolis, Brazil.Coimbra, Danilo Reis. Laboratory of Psychology of Sport and Exercise, Department of Physical Education, Center of Health Sciences and Sports, Santa Catarina State University, Florianopolis, Brazil.
AN  - 31697604
AU  - Andrade,
AU  - A.
AU  - Correia,
AU  - C.
AU  - K.
AU  - Coimbra,
AU  - D.
AU  - R.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/cyber.2019.0341
DP  - Ovid Technologies
J2  - Cyberpsychol Behav Soc Netw
L1  - internal-pdf://2131836642/cyber.2019.0341.pdf
LA  - English
N1  - Andrade, AlexandroCorreia, Clara KnierimCoimbra, Danilo Reis
PY  - 2019
SP  - 724-735
T2  - Cyberpsychology, behavior and social networking
TI  - The Psychological Effects of Exergames for Children and Adolescents with Obesity: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31697604
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31697604&amp;id=doi:10.1089%2Fcyber.2019.0341&amp;issn=2152-2715&amp;isbn=&amp;volume=22&amp;issue=11&amp;spage=724&amp;pages=724-735&amp;date=2019&amp;title=Cyberpsychology%2C+behavior+and+social+networking&amp;atitle=The+Psychological+Effects+of+Exergames+for+Children+and+Adolescents+with+Obesity%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Andrade&amp;pid=%3Cauthor%3EAndrade+A%3C%2Fauthor%3E%3CAN%3E31697604%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 22
ER  -
TY  - JOUR
AB  - Sexual assault is a significant problem among adolescents and college students in the U.S. One promising strategy for preventing sexual assault is the implementation of bystander programs, which encourage young people to intervene when witnessing incidents or warning signs of sexual assault. 

The evidence base for the effectiveness of bystander programs appears to be promising, but we know little about which programs are most effective in preventing sexual assault. This is a significant oversight, as bystander programs vary in content, particularly in their gendered framing of sexual assault. In this systematic review and meta-analysis, we synthesized high-quality research examining the effects of bystander programs on (1) bystander intervention and (2) self-reported perpetration of sexual assault. Paying special attention to a gendered approach as a moderator of program effects, we synthesized data from 14 independent studies (N = 7881). Twelve studies were randomized controlled trials and two used high-quality quasi-experimental designs. Findings indicated that bystander programs have a significant, desirable effect on bystander intervention, but no significant effect on sexual assault perpetration. 

Despite calls for sex-segregated implementation of sexual assault programs, we found no evidence that method of implementation (i.e., individual, single-sex group, mixed-sex group) moderated the effect of bystander programs on bystander intervention. Additionally, we found no evidence that gendered framing of sexual assault (i.e., portraying sexual assault as a gender-neutral problem or a gendered problem overwhelmingly affecting young women) moderated the effect of bystander programs. (PsycINFO Database Record (c) 2019 APA, all rights reserved)
AD  - Kettrey, Heather Hensman: hkettre@clemson.eduKettrey, Heather Hensman: Department of Sociology, Anthropology and Criminal Justice, Clemson University, 132 Brackett Hall, Clemson, SC, US, 29634, hkettre@clemson.eduKettrey, Heather Hensman: Department of Sociology, Anthropology and Criminal Justice, Clemson University, Clemson, SC, USMarx, Robert A.: Department of Child and Adolescent Development, San Jose State University, San Jose, CA, US
AN  - 2019-40117-001
AU  - Kettrey,
AU  - H.
AU  - H.
AU  - Marx,
AU  - R.
AU  - A.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10508-019-01503-1
DP  - Ovid Technologies
KW  - Sexual assault, Bystander, Meta-analysis, Adolescence, Prevention
KW  - *Intervention
KW  - *Prevention
KW  - *Sex Offenses
KW  - *Bystander Effect
KW  - College Students
KW  - Promotion &amp; Maintenance of Health &amp; Wellness [3365]
KW  - Human Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older)
L1  - internal-pdf://3228657783/Kettrey-2019.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2019
SP  - 2037-2053
T2  - Archives of Sexual Behavior
TI  - Does the gendered approach of bystander programs matter in the prevention of sexual assault among adolescents and college students? A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2019-40117-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10508-019-01503-1&amp;issn=0004-0002&amp;isbn=&amp;volume=48&amp;issue=7&amp;spage=2037&amp;pages=2037-2053&amp;date=2019&amp;title=Archives+of+Sexual+Behavior&amp;atitle=Does+the+gendered+approach+of+bystander+programs+matter+in+the+prevention+of+sexual+assault+among+adolescents+and+college+students%3F+A+systematic+review+and+meta-analysis.&amp;aulast=Kettrey&amp;pid=%3Cauthor%3EKettrey%2C+Heather+Hensman%3C%2Fauthor%3E%3CAN%3E2019-40117-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10508-019-01503-1
UR  - https://link.springer.com/content/pdf/10.1007%2Fs10508-019-01503-1.pdf
VL  - 48
ER  -
TY  - JOUR
AB  - **OBJECTIVE:**
Parenting programs are the recommended strategy for the prevention and treatment of disruptive child behavior. Similar to most psychosocial interventions, it is unknown which components of parenting programs (ie, parenting techniques taught) actually contribute to program effects. Identifying what parents need to be taught to reduce disruptive child behavior can optimize intervention strategies, and refine theories on how parenting shapes disruptive child behavior. 

**METHOD: **
In two meta-analyses, we updated the evidence-base for effectiveness of parenting programs delivered at various levels of prevention and treatment of disruptive behavior. We searched six databases (eg, PsycINFO, MEDLINE) for randomized trials and coded the parenting techniques taught in each program. We identified the techniques associated with program effects in general, and for prevention versus treatment, and immediate versus longer-term effects, specifically. 

**RESULTS: **
Parenting program effects on disruptive behavior gradually increased per level of prevention (universal d = -0.21, selective d = -0.27, indicated d = -0.55) and treatment (d = -0.69) (Meta-Analysis 1: 154 trials, 398 effect sizes). Three of 26 parenting techniques were associated with stronger program effects: positive reinforcement, praise in particular, and natural/logical consequences. Several additional techniques (eg, relationship building and parental self-management) were associated with stronger effects in treatment but weaker effects in prevention. No techniques were associated with stronger longer-term effects (Meta-Analysis 2: 42 trials, 157 effect sizes). 

**CONCLUSION: **
Positive reinforcement and nonviolent discipline techniques (eg, applying natural/logical consequences) seem to be key parenting program techniques to reduce disruptive child behavior. Additional techniques (eg, parental self-management skills) might improve program effects in treatment, but not in prevention.
AN  - 30738545
AU  - Leijten,
AU  - P.
AU  - Gardner,
AU  - F.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - van
AU  - Aar,
AU  - J.
AU  - Hutchings,
AU  - J.
AU  - Schulz,
AU  - S.
AU  - Knerr,
AU  - W.
AU  - Overbeek,
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jaac.2018.07.900
L1  - internal-pdf://0362355789/Leijten-2019-Meta-Analyses_ Key Parenting Prog.pdf
PY  - 2019
SP  - 180-190
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Meta-Analyses: Key Parenting Program Components for Disruptive Child Behavior
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30738545
UR  - https://ac.els-cdn.com/S0890856718319804/1-s2.0-S0890856718319804-main.pdf?_tid=659ea9e4-4223-44fc-98c0-4ba4c76d0415&amp;acdnat=1551877658_2e0daba2fd5baa4e2be79848054dcf00
VL  - 58
ER  -
TY  - JOUR
AB  - Developmental social pragmatic interventions are one treatment option for supporting the social communication and language skills of preschool children with autism spectrum disorder. Our first aim was to differentiate interventions using a developmental social pragmatic model from other developmental or naturalistic behavioral approaches. We applied explicit criteria outlining core features of developmental social pragmatic interventions to identify programs that use these core features.We then systematically reviewed studies examining the impact of developmental social pragmatic interventions in supporting (a) foundational social communication and language skills of preschool children with autism spectrum disorder and (b) caregiver interaction style. Additionally, we reviewed results exploring mediators and potential factors influencing children&#039;s response to developmental social pragmatic interventions. (PsycINFO Database Record (c) 2020 APA, all rights reserved)
AD  - Binns, Amanda V.: abinns3@uwo.caBinns, Amanda V.: Western University, London, ON, Canada, N6G 1H1, abinns3@uwo.caBinns, Amanda V.: University of Western Ontario, Elborn College, London, ON, CanadaCardy, Janis Oram: University of Western Ontario, Elborn College, London, ON, Canada
AN  - 2019-46145-001
AU  - Binns,
AU  - Amanda
AU  - V.
AU  - Cardy,
AU  - Janis
AU  - Oram
DA  - Jan
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/2396941518824497
DP  - Ovid Technologies
KW  - autism spectrum disorders, intervention/therapy, parent-child interaction therapy, preschool children, speech and language therapy
KW  - *Autism Spectrum Disorders
KW  - *Intervention
KW  - *Parent Child Communication
KW  - *Speech Therapy
KW  - *Language Therapy
KW  - Preschool Students
KW  - Social Communication
KW  - Developmental Disorders &amp; Autism [3250]
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human
L1  - internal-pdf://3020527495/binns.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2019
T2  - Autism &amp; Developmental Language Impairments Vol 4 2019, ArtID 2396941518824497
TI  - Developmental social pragmatic interventions for preschoolers with autism spectrum disorder: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2019-46145-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=2396-9415&amp;isbn=&amp;volume=4&amp;issue=&amp;spage=2396941518824497&amp;pages=&amp;date=2019&amp;title=Autism+%26+Developmental+Language+Impairments&amp;atitle=Developmental+social+pragmatic+interventions+for+preschoolers+with+autism+spectrum+disorder%3A+A+systematic+review.&amp;aulast=Binns&amp;pid=%3Cauthor%3EBinns%2C+Amanda+V%3C%2Fauthor%3E%3CAN%3E2019-46145-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 4
ER  -
TY  - JOUR
AB  - This study presents findings from three separate meta-analyses investigating differences between children placed in residential care and in family foster care with regard to three outcomes: internalizing behaviors, externalizing behaviors, and perception of care. Based on publications from the last 20 years, a total of 23 studies were included. The total sample consisted of 13,630 children in care, with 7,469 from foster care and 6,161 from residential care. The results from this study indicated that children in foster care had consistently better experiences and less problems across the three outcomes as compared to children in residential care. Analyses did not reveal evidence of publication bias, and sensitivity analyses also suggested that results were not influenced by individual studies. Additionally, moderation analyses revealed that the differences between foster and residential care could vary depending on certain factors such as the publication year, the gross domestic product of the country, and the length of care. The implications of differences in outcomes between the two placements are discussed.
AD  - Li, Dongdong. Centre for Research on Rehabilitation and Protection, Clinical and Forensic Psychology Branch, Ministry of Social and Family Development, Singapore, Singapore.Chng, Grace S. Centre for Research on Rehabilitation and Protection, Clinical and Forensic Psychology Branch, Ministry of Social and Family Development, Singapore, Singapore.Chu, Chi Meng. Centre for Research on Rehabilitation and Protection, Clinical and Forensic Psychology Branch, Ministry of Social and Family Development, Singapore, Singapore.
AN  - 29333987
AU  - Li,
AU  - D.
AU  - Chng,
AU  - G.
AU  - S.
AU  - Chu,
AU  - C.
AU  - M.
DA  - 12
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1524838017726427
DP  - Ovid Technologies
J2  - Trauma Violence Abuse Rev J
KW  - Adolescent
KW  - Adult
KW  - Child
KW  - Child Behavior Disorders/px [Psychology]
KW  - Female
KW  - *Foster Home Care/px [Psychology]
KW  - Humans
KW  - Internal-External Control
KW  - Juvenile Delinquency/px [Psychology]
KW  - Male
KW  - *Orphanages
KW  - *Quality of Life
KW  - Young Adult
L1  - internal-pdf://2226803549/Li-2019-Comparing Long-Term Placement Outcomes.pdf
LA  - English
M3  - Comparative Study
Meta-Analysis
N1  - Li, DongdongChng, Grace SChu, Chi Meng
PY  - 2019
SP  - 653-664
T2  - Trauma Violence &amp; Abuse
TI  - Comparing Long-Term Placement Outcomes of Residential and Family Foster Care: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=29333987
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29333987&amp;id=doi:10.1177%2F1524838017726427&amp;issn=1524-8380&amp;isbn=&amp;volume=20&amp;issue=5&amp;spage=653&amp;pages=653-664&amp;date=2019&amp;title=Trauma+Violence+%26+Abuse&amp;atitle=Comparing+Long-Term+Placement+Outcomes+of+Residential+and+Family+Foster+Care%3A+A+Meta-Analysis.&amp;aulast=Li&amp;pid=%3Cauthor%3ELi+D%3C%2Fauthor%3E%3CAN%3E29333987%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1524838017726427
VL  - 20
ER  -
TY  - JOUR
AB  - Sleep is an essential activity for human development. Often, children with autism spectrum disorder (ASD) are affected by a lack of sleep due to various types of sleep problems. We identified and analyzed studies that were aimed at utilizing sleep interventions for children with ASD. A systematic search of databases, reference lists, and ancestral searches identified 18 studies for inclusion. Studies were summarized in terms of (a) participants, (b) targeted sleep problem and measures, (d) intervention components, (e) research design and rigor, and (f) results. The aim of this review was to analyze the literature by evaluating the most commonly treated sleep problems, the various treatment components, and strength of the results using a between case parametric effect size estimate. The most commonly treated sleep problems were night wakings and bedtime disturbance. For interventions, all the studies incorporated multiple treatment components, most often including the use of a consistent bedtime routine. Effect size calculations indicated a moderate effect size, however, limited due to the small number of studies. Results suggest the overall effectiveness of behavioral interventions for the treatment of sleep problems for children with ASD. Based on our analysis, suggestions for practitioners regarding current practices and future directions for research are discussed. Copyright &copy; 2019, &copy; 2019 Taylor &amp; Francis Group, LLC.
AD  - (Carnett) San Antonio Applied Behavior Analysis Research Consortium, University of Texas at San Antonio, San Antonio, TX, United States (Hansen) Georgia State University, Atlanta, GA, United States (McLay) University of Canterbury, Christchurch, New Zealand (Neely) San Antonio Applied Behavior Analysis Research Consortium, University of Texas San Antonio, San Antonio, TX, United States (Lang) Clinic for Autism Research Evaluation and Support, Texas State University, San Marcos, TX, United StatesA. Carnett, Department of Educational Psychology, The University of Texas at San Antonio, 501 W. Cesar E. Chavez Blvd, San Antonio, TX 78207, United States. E-mail: Amarie.Carnett@utsa.edu
AN  - 628803627
AU  - Carnett,
AU  - A.
AU  - Hansen,
AU  - S.
AU  - McLay,
AU  - L.
AU  - Neely,
AU  - L.
AU  - Lang,
AU  - R.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/17518423.2019.1646340
DP  - Ovid Technologies
KW  - autism
KW  - quantitative-analysis
KW  - review
KW  - sleep intervention
KW  - Sleep problems
KW  - article
KW  - calculation
KW  - child
KW  - drug combination
KW  - effect size
KW  - human
KW  - physician
KW  - quantitative analysis
KW  - rigor
KW  - sleep debt
KW  - wakefulness
L1  - internal-pdf://2143085644/Carnett-2019.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2019
PY  - 2019
T2  - Developmental Neurorehabilitation.
TI  - Quantitative-Analysis of Behavioral Interventions to Treat Sleep Problems in Children with Autism
UR  - http://www.tandfonline.com/loi/ipdr20
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=628803627
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:31355702&amp;id=doi:10.1080%2F17518423.2019.1646340&amp;issn=1751-8423&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2019&amp;title=Developmental+Neurorehabilitation&amp;atitle=Quantitative-Analysis+of+Behavioral+Interventions+to+Treat+Sleep+Problems+in+Children+with+Autism&amp;aulast=Carnett&amp;pid=%3Cauthor%3ECarnett+A.%3C%2Fauthor%3E%3CAN%3E628803627%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/full/10.1080/17518423.2019.1646340
ER  -
TY  - JOUR
AB  - Regarding interventions for SGMY, this review identified 9 interventions for mental health, 2 for substance use, and 1 for violence victimization. 

CONTEXT: Compared with cisgender (nontransgender), heterosexual youth, sexual and gender minority youth (SGMY) experience great inequities in substance use, mental health problems, and violence victimization, thereby making them a priority population for interventions.

OBJECTIVE: To systematically review interventions and their effectiveness in preventing or reducing substance use, mental health problems, and violence victimization among SGMY.

DATA SOURCES: PubMed, PsycINFO, and Education Resources Information Center.

STUDY SELECTION: Selected studies were published from January 2000 to 2019, included randomized and nonrandomized designs with pretest and posttest data, and assessed substance use, mental health problems, or violence victimization outcomes among SGMY.

DATA EXTRACTION: Data extracted were intervention descriptions, sample details, measurements, results, and methodologic rigor.

RESULTS: With this review, we identified 9 interventions for mental health, 2 for substance use, and 1 for violence victimization. One SGMY-inclusive intervention examined coordinated mental health services. Five sexual minority-specific interventions included multiple state-level policy interventions, a therapist-administered family-based intervention, a computer-based intervention, and an online intervention. Three gender minority-specific interventions included transition-related gender-affirming care interventions. All interventions improved mental health outcomes, 2 reduced substance use, and 1 reduced bullying victimization. One study had strong methodologic quality, but the remaining studies&#039; results must be interpreted cautiously because of suboptimal methodologic quality.

LIMITATIONS: There exists a small collection of diverse interventions for reducing substance use, mental health problems, and violence victimization among SGMY.

CONCLUSIONS: The dearth of interventions identified in this review is likely insufficient to mitigate the substantial inequities in substance use, mental health problems, and violence among SGMY.
AD  - [Coulter, Robert W. S.; Egan, James E.; Kinsky, Suzanne; Frankeberger, Jessica; Folb, Barbara L.; Mair, Christina; Stall, Ron; Miller, Elizabeth] Univ Pittsburgh, Dept Behav &amp; Community Hlth Sci, Grad Sch Publ Hlth, Pittsburgh, PA USA. [Friedman, M. Reuel] Univ Pittsburgh, Dept Infect Dis &amp; Microbiol, Grad Sch Publ Hlth, Pittsburgh, PA USA. [Coulter, Robert W. S.; Egan, James E.; Kinsky, Suzanne; Friedman, M. Reuel; Markovic, Nina; Silvestre, Anthony; Stall, Ron] Univ Pittsburgh, Grad Sch Publ Hlth, Ctr LGBT Hlth Res, Pittsburgh, PA USA. [Markovic, Nina] Univ Pittsburgh, Sch Dent Med, Dept Dent Publ Hlth, Pittsburgh, PA USA. [Coulter, Robert W. S.] Univ Pittsburgh, Sch Med, Dept Med, Pittsburgh, PA USA. [Folb, Barbara L.] Univ Pittsburgh, Hlth Sci Lib Syst, Pittsburgh, PA USA. [Eckstrand, Kristen L.] Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA. [Kinsky, Suzanne] UPMC, Ctr High Value Hlth Care, Pittsburgh, PA USA. [Coulter, Robert W. S.; Miller, Elizabeth] Univ Pittsburgh, Sch Med, Dept Pediat, Pittsburgh, PA USA. [Coulter, Robert W. S.; Miller, Elizabeth] UPMC, Childrens Hosp Pittsburgh, Div Adolescent &amp; Young Adult Med, Pittsburgh, PA USA.Coulter, RWS (reprint author), Univ Pittsburgh, Grad Sch Publ Hlth, 6129 Publ Hlth Bldg,130 De Soto St, Pittsburgh, PA 15261 USA.robert.ws.coulter@pitt.edu
AN  - WOS:000484526900005
AU  - Coulter,
AU  - R.
AU  - W.
AU  - S.
AU  - Egan,
AU  - J.
AU  - E.
AU  - Kinsky,
AU  - S.
AU  - Friedman,
AU  - M.
AU  - R.
AU  - Eckstrand,
AU  - K.
AU  - L.
AU  - Frankeberger,
AU  - J.
AU  - Folb,
AU  - B.
AU  - L.
AU  - Mair,
AU  - C.
AU  - Markovic,
AU  - N.
AU  - Silvestre,
AU  - A.
AU  - Stall,
AU  - R.
AU  - Miller,
AU  - E.
DA  - Sep
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1542/peds.2018-3367
J2  - Pediatrics
KW  - sexual orientation disparities
KW  - gender identity disorder
KW  - puberty
KW  - suppression
KW  - substance use
KW  - adolescents findings
KW  - structural stigma
KW  - cigarette-smoking
KW  - young-adults
KW  - transgender
KW  - gay
KW  - Pediatrics
L1  - internal-pdf://4170442007/Coulter-2019.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: IV8PGTimes Cited: 0Cited Reference Count: 81Coulter, Robert W. S. Egan, James E. Kinsky, Suzanne Friedman, M. Reuel Eckstrand, Kristen L. Frankeberger, Jessica Folb, Barbara L. Mair, Christina Markovic, Nina Silvestre, Anthony Stall, Ron Miller, ElizabethNational Institute on Drug AbuseUnited States Department of Health &amp; Human ServicesNational Institutes of Health (NIH) - USANIH National Institute on Drug Abuse (NIDA) [F31DA037647]; National Center for Advancing Translational SciencesUnited States Department of Health &amp; Human ServicesNational Institutes of Health (NIH) - USANIH National Center for Advancing Translational Sciences (NCATS) [TL1TR001858]; National Institute on Alcohol Abuse and AlcoholismUnited States Department of Health &amp; Human ServicesNational Institutes of Health (NIH) - USANIH National Institute on Alcohol Abuse &amp; Alcoholism (NIAAA) [K01AA027564]; Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentUnited States Department of Health &amp; Human ServicesNational Institutes of Health (NIH) - USANIH Eunice Kennedy Shriver National Institute of Child Health &amp; Human Development (NICHD) [K24HD075862]; National Institutes of Health (NIH)United States Department of Health &amp; Human ServicesNational Institutes of Health (NIH) - USASupported by the National Institute on Drug Abuse (award F31DA037647 to Dr Coulter), the National Center for Advancing Translational Sciences (TL1TR001858 to Dr Coulter), the National Institute on Alcohol Abuse and Alcoholism (K01AA027564 to Dr Coulter), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (K24HD075862 to Dr Miller). The opinions expressed in this work are those of the authors and do not necessarily represent those of the funders. Funded by the National Institutes of Health (NIH).0Amer acad pediatricsElk grove village1098-4275
PY  - 2019
SP  - 20
T2  - Pediatrics
TI  - Mental Health, Drug, and Violence Interventions for Sexual/Gender Minorities: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000484526900005
UR  - https://pediatrics.aappublications.org/content/144/3/e20183367?sso=1&amp;sso_redirect_count=1&amp;nfstatus=401&amp;nftoken=00000000-0000-0000-0000-000000000000&amp;nfstatusdescription=ERROR%3a+No+local+token
VL  - 144
ER  -
TY  - JOUR
AB  - Substance-exposed newborns (SENs) are at increased risk of child maltreatment, out-of-home placement, and poor health and developmental outcomes. The purpose of this systematic review is to synthesize existing research on community- and home-based interventions designed to improve parenting and reduce risk of maltreatment for families with SENs, applying a program logic framework. The review includes studies that used preexperimental, quasi-experimental, and experimental designs. Twelve interventions were identified. Of the nine studies that used more rigorous experimental or quasi-experimental designs, five showed positive effects on at least one parenting or child maltreatment outcome, although some studies showed high risk of bias. Full coherence among the intended participants, theory of change, and program components was observed for only two interventions. The findings suggest a need for more rigorous research to develop and test interventions that are grounded in theory and prior research and that address the unique needs of families with SENs.
AD  - [West, Allison L.; Gagliardi, Laina; Correll, Leeya; Lilli, Alexandra Cirillo; Daniels, Jane] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Populat Family &amp; Reprod Hlth, 615 N Wolfe St, Baltimore, MD 21205 USA. [Dauber, Sarah] Ctr Addict, New York, NY USA.West, AL (reprint author), Johns Hopkins Bloomberg Sch Publ Hlth, Dept Populat Family &amp; Reprod Hlth, 615 N Wolfe St, Baltimore, MD 21205 USA.awest25@jhu.edu
AN  - WOS:000483169800001
AU  - West,
AU  - A.
AU  - L.
AU  - Dauber,
AU  - S.
AU  - Gagliardi,
AU  - L.
AU  - Correll,
AU  - L.
AU  - Lilli,
AU  - A.
AU  - C.
AU  - Daniels,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1177/1077559519866272
J2  - Child Maltreatment
KW  - intervention studies
KW  - substance abuse
KW  - parenting
KW  - child maltreatment
KW  - neonatal abstinence syndrome
KW  - abuse treatment
KW  - united-states
KW  - visiting
KW  - programs
KW  - toddlers program
KW  - mothers
KW  - women
KW  - infants
KW  - services
KW  - attachment
KW  - Family Studies
KW  - Social Work
L1  - internal-pdf://1828252419/West.pdf
LA  - English
M3  - Review; Early Access
N1  - ISI Document Delivery No.: IT8ZGTimes Cited: 0Cited Reference Count: 76West, Allison L. Dauber, Sarah Gagliardi, Laina Correll, Leeya Lilli, Alexandra Cirillo Daniels, JaneAnnie E. Casey FoundationThe author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was funded in part by the Annie E. Casey Foundation. We thank them for their support.02Sage publications incThousand oaks1552-6119
PY  - 2019
SP  - 15
T2  - Child Maltreatment
TI  - Systematic Review of Community- and Home-Based Interventions to Support Parenting and Reduce Risk of Child Maltreatment Among Families With Substance-Exposed Newborns
UR  - &lt;Go to ISI&gt;://WOS:000483169800001
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** 
To assess the efficacy of desmopressin, alarm, desmopressin plus alarm, and desmopressin plus anticholinergic agent (AA) therapy in the management of paediatric monosymptomatic nocturnal enuresis (MNE) using a network meta-analysis.

**MATERIALS AND METHODS:** 
We searched the electronic databases PubMed, Cochrane Library, EMBASE and Web of Science from inception to 1 March 2018. Randomized controlled trials (RCTs) that compared desmopressin, alarm, desmopressin plus alarm, and desmopressin plus AAs were identified. The network meta-analysis was conducted with software R 3.3.2 and STATA 14.0.

**RESULTS:** 
Eighteen RCTs with a total of 1 649 participants were included. The meta-analysis results showed that complete response (CR) and success rates with desmopressin plus AAs were higher than with desmopressin or alarm monotherapy. Success rates for desmopressin plus alarm therapy were higher than for alarm monotherapy. No obvious difference was observed between desmopressin plus AAs and desmopressin plus alarm therapy with regard to CR rate and success rate. The relapse rate with alarm monotherapy was much lower than with desmopressin monotherapy. Adverse events seemed to be infrequently and tolerable for all treatments. The ranking probability results were as follows: desmopressin plus AA ranked first for the outcomes of CR and success, desmopressin plus alarm therapy ranked first for mean number of wet nights per week, and alarm therapy had the lowest relapse rate.

**CONCLUSIONS:** 
The network meta-analysis showed that desmopressin had similar efficacy to alarm therapy but a higher relapse rate. Desmopressin plus AA therapy was associated with better efficacy than and a similar relapse rate to desmopressin monotherapy. Desmopressin plus alarm therapy was similar to both desmopressin and alarm monotherapy in efficacy. All treatments, including desmopressin plus AAwere associated with tolerable adverse events; however, additional high-quality studies are needed for further evaluation of these treatments.
AD  - Song, Pan. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.Huang, Chuiguo. Department of Urology, Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.Wang, Yan. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.Wang, Qingwei. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.Zhu, Wen. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.Yue, Yiwei. College of Clinical Medicine, Zhengzhou University, Zhengzhou, Henan Province, China.Wang, Wancong. Department of Digest, The fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.Feng, Jinjin. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.He, Xiangfei. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.Cui, Lingang. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.Wan, Tingxiang. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.Wen, Jianguo. Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, China.
AN  - 30216627
AU  - Song,
AU  - P.
AU  - Huang,
AU  - C.
AU  - Wang,
AU  - Y.
AU  - Wang,
AU  - Q.
AU  - Zhu,
AU  - W.
AU  - Yue,
AU  - Y.
AU  - Wang,
AU  - W.
AU  - Feng,
AU  - J.
AU  - He,
AU  - X.
AU  - Cui,
AU  - L.
AU  - Wan,
AU  - T.
AU  - Wen,
AU  - J.
DA  - 03
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/bju.14539
DP  - Ovid Technologies
J2  - BJU Int
KW  - *Antidiuretic Agents/tu [Therapeutic Use]
KW  - Child
KW  - *Cholinergic Antagonists/tu [Therapeutic Use]
KW  - *Clinical Alarms
KW  - *Deamino Arginine Vasopressin/tu [Therapeutic Use]
KW  - Humans
KW  - Network Meta-Analysis
KW  - *Nocturnal Enuresis/dt [Drug Therapy]
KW  - Nocturnal Enuresis/pp [Physiopathology]
KW  - Randomized Controlled Trials as Topic
KW  - Recurrence
KW  - Treatment Outcome
KW  - 0 (Antidiuretic Agents)
KW  - 0 (Cholinergic Antagonists)
KW  - ENR1LLB0FP (Deamino Arginine Vasopressin)
L1  - internal-pdf://1335449233/Song_et_al-2019-BJU_International.pdf
LA  - English
M3  - Review
N1  - Song, PanHuang, ChuiguoWang, YanWang, QingweiZhu, WenYue, YiweiWang, WancongFeng, JinjinHe, XiangfeiCui, LingangWan, TingxiangWen, Jianguo
PY  - 2019
SP  - 388-400
T2  - BJU International
TI  - Comparison of desmopressin, alarm, desmopressin plus alarm, and desmopressin plus anticholinergic agents in the management of paediatric monosymptomatic nocturnal enuresis: a network meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=30216627
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30216627&amp;id=doi:10.1111%2Fbju.14539&amp;issn=1464-4096&amp;isbn=&amp;volume=123&amp;issue=3&amp;spage=388&amp;pages=388-400&amp;date=2019&amp;title=BJU+International&amp;atitle=Comparison+of+desmopressin%2C+alarm%2C+desmopressin+plus+alarm%2C+and+desmopressin+plus+anticholinergic+agents+in+the+management+of+paediatric+monosymptomatic+nocturnal+enuresis%3A+a+network+meta-analysis.&amp;aulast=Song&amp;pid=%3Cauthor%3ESong+P%3C%2Fauthor%3E%3CAN%3E30216627%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/bju.14539
VL  - 123
ER  -
TY  - JOUR
AB  - The eating disorder clinical and scientific community advocates for the use of a shared approach to healthcare that actively involves patients and carers. A systematic review of the literature on guided self-help or self-help in anorexia nervosa (targeting either the individual affected by the illness or their carers) and meta-analyses of studies using randomised controlled designs for the evaluation of the outcomes: (1) drop-out from end-of-treatment assessment, (2) body mass index (BMI), (3) anxiety, (4) depression and (5) quality of life, were undertaken. Guided self-help was directed to patients in 15 studies and to carers in seven studies. The interventions were based on a variety of theoretical models, used different formats (books and digital materials), and were delivered by individuals with a range of experiences and expertise (e.g. individuals with lived experience of the illness, graduate students, or clinically trained professionals). Guided self-help was associated with significantly lower drop-out from the completion of end-of-treatment assessments compared to a control condition. There was an improvement in carers&#039; wellbeing from skill-sharing interventions. Guided self-help may facilitate patients&#039; treatment engagement and also improve carers&#039; wellbeing. Copyright &copy; 2019, &copy; 2019 Institute of Psychiatry and Johns Hopkins University.
AN  - 628409915
AU  - Albano,
AU  - G.
AU  - Hodsoll,
AU  - J.
AU  - Kan,
AU  - C.
AU  - Lo
AU  - Coco,
AU  - G.
AU  - Cardi,
AU  - V.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/09540261.2019.1588711
L1  - internal-pdf://0443146812/Albano-2019-Task-sharing interventions for pat.pdf
PY  - 2019
SP  - 367-381
T2  - International Review of Psychiatry
TI  - Task-sharing interventions for patients with anorexia nervosa or their carers: a systematic evaluation of the literature and meta-analysis of outcomes
UR  - http://www.tandfonline.com/loi/iirp20
UR  - https://www.tandfonline.com/doi/full/10.1080/09540261.2019.1588711
VL  - 31
ER  -
TY  - JOUR
AB  - **Background**
Exposure to different types of trauma have been associated with varying types and complexity of adverse outcomes, including adverse effects on cognitive functioning, attention, memory, academic performance, and school‐related behaviors. Given the growing research on trauma and increased knowledge about the prevalence, consequences and costs associated with trauma, there have been increased efforts at the local, state and federal levels to make systems &ldquo;trauma‐informed&rdquo; (Lang et al., 2015). Indeed, federal legislation has been proposed to advance trauma‐informed practice, with approximately 49 bills introduced between 1973 and 2015 that explicitly mentioned trauma‐informed practice, with more than half introduced in 2015 alone (Purtle &amp; Lewis, 2017). The promotion and provision of trauma‐informed approaches in school settings in particular is growing at a rapid rate across the United States. At least 17 states have implemented trauma‐informed approaches at the school, district, and even state‐wide levels (Overstreet &amp; Chafouleas, 2016). This rapid increase in the growth of trauma‐informed approaches in schools has been fueled by a number of local, state, and federal initiatives and increasing support by education related organizations. While the intent of creating trauma‐informed approaches in schools is a noble one, relatively little is known about the benefits, costs, and how trauma‐informed approaches are being defined and evaluated (Berliner &amp; Kolko, 2016). Adopting a trauma‐informed approach in a complex system such as a school building or district is a time consuming and potentially costly endeavor, and there is potential for harm; therefore, it is important to assess the effects of this approach to inform policy and practice.

**Objectives**
The purpose of this review was to identify, describe and synthesize the evidence of effects of trauma‐informed approaches in schools to provide guidance for policymakers and educators and to identify important gaps in the evidence base.

**Search methods**
We conducted a search for published and unpublished studies using a comprehensive search that included nine electronic databases and searches of various research registers, gray literature sources, reference lists of prior reviews and relevant studies, and contacts with authors and researchers in the field of trauma and school‐based intervention research.

**Selection criteria**
Criteria for inclusion in the review included:

1.Must have used a randomized or quasi‐experimental study design in which participants who received an intervention were compared with a wait‐list, no treatment, treatment‐as‐usual or an alternative treatment comparison group.

2.Studies must have been conducted in a school setting serving PreK‐12 (or equivalent) students.

3.Studies must have assessed effects of a trauma‐informed approach, defined as a program, organization, or system that realizes the impact of trauma, recognizes the symptoms of trauma, responds by integrating knowledge about trauma policies and practices, and seeks to reduce retraumatization. At last two of the three key elements of a trauma‐informed approach must have been present: Workforce development, trauma‐focused services, and organizational environment and practices (Hanson &amp; Lang, 2016). This approach is distinguished from trauma‐specific interventions, which are specific interventions designed to treat or otherwise address the impact/symptoms of trauma and facilitate healing.

4.Studies must have measured a student‐level outcome related to trauma symptoms/mental health, academic performance, behavior, or socioemotional functioning.

5.We did not limit studies based on publication status, geographical location or language. We searched for studies that had been published in the last 10 years, as this is a relatively recent movement

**Data collection and analysis**
One reviewer searched all sources and uploaded all potentially relevant citations to Covidence, a systematic review software, for further screening by two reviewers. Two reviewers then independently screened each of the full‐text reports for eligibility using a screening instrument. Disagreements related to eligibility were discussed and resolved between the two reviewers. Data extraction and analysis was not possible due to no studies having met criteria for inclusion in the review.

**Results**
A total of 9,102 references from all searches were imported to Covidence for screening. After removal of 1,929 duplicates, 7,173 titles/abstracts were screened, and 7,106 studies were excluded. The remaining 67 studies were assessed for full‐text eligibility by two independent reviewers. All 67 studies were excluded: 49 were neither an randomized controlled trial (RCT) nor quasi‐experimental design (QED); 12 did not examine effects of a trauma‐informed approach; 5 examined only one aspect of a trauma‐informed approach (only workforce OR organizational OR practice changes); one was not a school‐based intervention. Some studies may have been excluded for multiple reasons; however, only the first (primary) reason for exclusion was recorded. See Figure 1 for flowchart of the search and selection process. A full list of excluded studies can be found in References to Excluded Studies.

No studies met criteria for inclusion in this review.

**Authors&#039; conclusions**
Trauma‐informed approaches are being promoted and used across child‐serving systems, and the number of states and school districts adopting trauma‐informed approaches in schools is growing rapidly (Overstreet &amp; Chafouleas, 2016). While the premise of a trauma‐informed schools approach is a noble one, it is unclear as to whether the promise of this framework is actually delivering the types of systemic and programmatic changes intended, and if those changes are resulting in the outcomes the proponents of a trauma‐informed approach in schools hoped for. The purpose of this systematic review was to find, describe, evaluate, and synthesize effects of trauma‐informed approaches in schools to inform policy and practice. While there are a number of publications that describe trauma‐informed approaches, advocate for the need for trauma‐informed approaches, and discuss the potential benefits of adopting such an approach in schools, we found no rigorous evaluations through our extensive search process.

From this review, it seems like the most prudent action for school leaders, policymakers, and school mental health professionals to do would be to proceed with caution in their embrace of a trauma‐informed approach as an overarching framework and begin evaluating these programs. We simply do not have the evidence (yet) to know if this approach works, and indeed, we also do not know if implementing trauma‐informed approaches in schools could have unintended negative consequences for traumatized youth and school communities. We also do not have evidence of other potential costs in implementing this approach in schools, whether they be financial, academic, or other opportunity costs, and whether benefits outweigh the costs of implementing and maintaining this approach in schools.

That said, calling for caution in adopting a trauma‐informed approach in schools does not preclude schools from continuing to implement evidence‐informed programs that target trauma symptoms in youth, or that they should simply wait for the research to provide unequivocal answers. We do encourage healthy skepticism and evaluation by the schools who are adopting a trauma‐informed approach and clear descriptions of what schools are doing. Currently, despite several theoretical and guidance documents, it is not clear exactly what schools are doing when they say they are using a trauma‐informed approach. Not only do we need more research on the effects, but descriptive and qualitative research on what is actually being implemented would be a welcome addition to the empirical literature in this area. We suspect that schools may be calling what they are doing a trauma‐informed approach, but what is actually being done from school to school or district to district may vary quite widely in the practice and implementation of this approach. Clearly, rigorous research is needed in assessing the effects of using a trauma‐informed approach in schools and we encourage rigorously designed studies in this area. Evaluating complex interventions such as this is not easy and requires resources. Drawing from research on multi‐tiered approaches in schools could help inform research approaches to assess the effects (and costs) of trauma‐informed approaches in schools.
AU  - Maynard
AU  - ,
AU  - B.
AU  - R.
AU  - Farina,
AU  - A.
AU  - Dell,
AU  - N.
AU  - A.
AU  - Kelly,
AU  - M.
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/cl2.1018
L1  - internal-pdf://3510029605/Maynard-2019-Effects of trauma‐informed approa.pdf
PY  - 2019
T2  - Campbell Systematic Reviews
TI  - Effects of trauma‐informed approaches in schools: A systematic review
ER  -
TY  - JOUR
AB  - **Importance: **
Depression during pregnancy and the postpartum period is relatively common and can have adverse effects on both mother and child. 

**Objective: **
To systematically review benefits and harms of primary care-relevant interventions to prevent perinatal depression, a major or minor depressive episode during pregnancy or up to 1 year after childbirth, to inform the US Preventive Services Task Force. 

**Data Sources: **
MEDLINE, PubMED (for publisher-supplied records only), PsycINFO, and the Cochrane Central Register of Controlled Trials; surveillance through December 5, 2018. 

**Study Selection: **
Randomized clinical trials (RCTs) and nonrandomized controlled intervention studies of interventions (eg, behavior-based, antidepressants, dietary supplements) to prevent perinatal depression in general populations of pregnant and postpartum individuals or in those at increased risk of perinatal depression. Large cohort studies were considered for harms of antidepressant use only. 

**Data Extraction and Synthesis: **
Two investigators independently reviewed abstracts and full-text articles and quality rated included studies. Random-effects meta-analysis was used to estimate the benefits of the interventions. 

**Main Outcomes and Measures: **
Depression status; depression symptoms; maternal, infant, and child health outcomes. 

**Results: **
Fifty studies (N = 22385) that met inclusion criteria were identified. Counseling interventions were the most widely studied interventions. Compared with controls, counseling interventions were associated with a lower likelihood of onset of perinatal depression (pooled risk ratio [RR], 0.61 [95% CI, 0.47-0.78]; 17 RCTs [n = 3094]; I2 = 39.0%). The absolute difference in the risk of perinatal depression ranged from 1.3% greater reduction in the control group to 31.8% greater reduction in the intervention group. Health system interventions showed a benefit in 3 studies (n = 5321) and had a pooled effect size similar to that of the counseling interventions, but the pooled effect was not statistically significant using a method appropriate for pooling a small number of studies (restricted maximum likelihood RR, 0.58 [95% CI, 0.22-1.53]; n = 4738; I2 = 66.3%; absolute risk reduction range, -3.1% to -13.1%). None of the behavior-based interventions reported on harms directly. A smaller percentage of participants prescribed sertraline had a depression recurrence compared with those prescribed placebo (7% vs 50%, P = .04) at 20 weeks postpartum in 1 very small RCT (n = 22 analyzed) but with an increased risk of adverse effects to the mother. 

**Conclusions and Relevance:**
Counseling interventions can be effective in preventing perinatal depression, although most evidence was limited to women at increased risk for perinatal depression. A variety of other intervention approaches provided some evidence of effectiveness but lacked a robust evidence base and need further research.
AN  - 30747970
AU  - O&#039;Connor,
AU  - E.
AU  - Senger,
AU  - C.
AU  - A.
AU  - Henninger,
AU  - M.
AU  - L.
AU  - Coppola,
AU  - E.
AU  - Gaynes,
AU  - B.
AU  - N.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1001/jama.2018.20865
L1  - internal-pdf://1590370154/O&#039;Connor-2019-Interventions to Prevent Perinat.pdf
PY  - 2019
SP  - 588-601
T2  - JAMA
TI  - Interventions to Prevent Perinatal Depression: Evidence Report and Systematic Review for the US Preventive Services Task Force
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30747970
UR  - https://watermark.silverchair.com/jama_oconnor_2019_us_180028.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAhQwggIQBgkqhkiG9w0BBwagggIBMIIB_QIBADCCAfYGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM79jvjPvCUTylPQbpAgEQgIIBxygPwbLJqYdSUE3XaAdvnc3BE2Ae1k_sfKeX477-AO7IHDV81WZZqT_6bIipJAkzd-qrsYJGT7e_KsAMpRgU_X_9IvQuv4WkRvGvsW1_em34qJWbyQvLdju24e5eR915DiJegB0OJpG6AiGA_xflmTDTOZh3N9f3MJ89fubAiMsFWKkjJQSpXqtPnrThn8hprr8MwOWLB2pewBTVGeW5m61p3UDh3ACKpMN0inkJHW1Ql8BhSLal-rkg5WTmV_Y7mKHAYyGGbbKQPPA4hAP8IizcJ9tHlHMob-rFqQutyJL4lJx5i-5Q6WqK9RY1CFSVHpCx7LEfyMhSOGjAjcl4BOZw-oy6UjC2Mkoij_IKjxzrP7dZrXAT5di7b17ajTTLimMcxlKQ-qgbj38eijWow8hnxn7LF-He9XZ0oslzWyJWNasf9AwfGhqEY2ckafZzPmCEUMuMs1mYMVLzVT1GqrMnz7OZnTDeqyoCWNiyVG8VSPXfXrsbvpRpZME34A1Kkk7gqs_mGSB65b0A_p7YOcT77mg6f86rs2qOrP9MO6TZvo-yerK_7YAJxe_u9YZUZSOAasIUozekxamw45aQ9i2xFMV-GoKS
VL  - 321
ER  -
TY  - JOUR
AB  - This meta-review summarizes existing evidence from systematic reviews and meta-analyses on the effectiveness of school-based psychological interventions aimed at improving student mental health and well-being, and preventing mental illness. Systematic reviews and meta-analyses were identified via the electronic databases PsycINFO, Web of Knowledge, Medline, Embase, and HMIC (Health Management Information Consortium). Ten systematic reviews and meta-analysis were eligible for inclusion in the final analyses. These systematic reviews and meta-analyses evaluated the effects of five types of school-based psychological interventions: Mindfulness, Social Emotional Learning, Cognitive Behavioral Therapy, Yoga, and Body-Image. Overall effectiveness reported in the included studies was significant for the most part, and ranging from small to large with respect to the effect size. The authors of all of the studies emphasized the need for additional high-quality trials to further examine the effectiveness of school-based psychological interventions aimed at improving student mental health and well-being, and preventing mental illness.
AN  - 31140100
AU  - Soulakova,
AU  - B.
AU  - Kasal,
AU  - A.
AU  - Butzer,
AU  - B.
AU  - Winkler,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10935-019-00552-5
L1  - internal-pdf://4199917440/Soulakova-2019-Meta-Review on the Effectivenes.pdf
PY  - 2019
SP  - 28
T2  - Journal of Primary Prevention
TI  - Meta-Review on the Effectiveness of Classroom-Based Psychological Interventions Aimed at Improving Student Mental Health and Well-Being, and Preventing Mental Illness
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31140100
UR  - https://link.springer.com/article/10.1007%2Fs10935-019-00552-5
VL  - 28
ER  -
TY  - JOUR
AB  - *Purpose:* 
To examine the effects of Treatment Foster Care on youth with serious behavior problems. 

*Method:* 
Included studies are controlled trials with high or medium quality, published between 1990 and September 2017. The control group consists of youth with serious behavior problems in group care, and the follow-up time was at least 12 months. The review also examines ethical and economic aspects. 

*Results:* 
A total of eight controlled studies were included, consisting of 633 young people and 55 effect sizes. All studies examined the same model, Treatment Foster Care Oregon (TFCO). There is moderate certainty of evidence that TFCO reduces the risk of future criminal behavior and the number of days in locked settings. Furthermore, there is low certainty of evidence that TFCO reduces the risk of delinquent peer associations, drug use, and depression. 

*Discussion:* 
TFCO is to be preferred to group care for youth with serious behavior problems. Ethical and economic implications are discussed.
AD  - [Astrom, Therese; Hakansson, Kickan; Jonsson, Ann Kristine; Wiss, Johanna; Sundell, Knut] Swedish Agcy Hlth Technol Assessment &amp; Assessment, St Eriksgatan 117, S-11343 Stockholm, Sweden. [Bergstrom, Martin] Lund Univ, Sch Social Work, Lund, Sweden. [Munthe, Christian] Univ Gothenburg, Dept Philosophy Linguist &amp; Theory Sci, Gothenburg, Sweden. [Wirtberg, Ingegerd] Lund Univ, Dept Psychol, Lund, Sweden. [Sundell, Knut] Karolinska Inst, Med Management Ctr, Dept Learning Informat Management &amp; Eth, Stockholm, Sweden.Astrom, T (reprint author), Swedish Agcy Hlth Technol Assessment &amp; Assessment, St Eriksgatan 117, S-11343 Stockholm, Sweden.therese.astrom@sbu.se
AN  - WOS:000506745400001
AU  - Astrom,
AU  - T.
AU  - Bergstrom,
AU  - M.
AU  - Hakansson,
AU  - K.
AU  - Jonsson,
AU  - A.
AU  - K.
AU  - Munthe,
AU  - C.
AU  - Wirtberg,
AU  - I.
AU  - Wiss,
AU  - J.
AU  - Sundell,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1177/1049731519890394
J2  - Res. Soc. Work. Pract.
KW  - Treatment Foster Care
KW  - delinquency
KW  - adolescents
KW  - group care
KW  - institutional care
KW  - out-of-home placement
KW  - randomized controlled-trial
KW  - institutional youth care
KW  - 2-year follow-up
KW  - outcomes
KW  - children
KW  - girls
KW  - mtfc
KW  - trajectories
KW  - prevention
KW  - symptoms
KW  - Social Work
L1  - internal-pdf://3574305288/Astrom-Treatment Foster Care Oregon for Delinq.pdf
LA  - English
M3  - Review; Early Access
N1  - ISI Document Delivery No.: KB8NLTimes Cited: 0Cited Reference Count: 61Astrom, Therese Bergstrom, Martin Hakansson, Kickan Jonsson, Ann Kristine Munthe, Christian Wirtberg, Ingegerd Wiss, Johanna Sundell, Knut0Sage publications incThousand oaks1552-7581
PY  - 2019
SP  - 13
T2  - Research on Social Work Practice
TI  - Treatment Foster Care Oregon for Delinquent Adolescents: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000506745400001
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1049731519890394
ER  -
TY  - JOUR
AB  - **Introduction:** 
The multifactorial nature of Autism Spectrum Disorder (ASD) is the reason why complementary and alternative methods of treatment are sought in order to support the classic approach. 

**Objective(s):** 
The aim of the study was to assess the effectiveness of Equine-Assisted Activities and Therapies (EAAT) in ASD patients based on a review of the literature. 

**Method(s):** 
A review of the literature and a meta-analysis were conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PUBMED, Cochrane Library, Web of Science, ClinicalTrials.gov and PEDro databases were searched until July 20, 2017. Only articles published in English, in a journal with a review process, after 1999, with a control group or presentation of comparative pre-/post-therapy results in ASD patients, and clear inclusion/exclusion criteria were considered. The methodological quality of the included studies was assessed using the Quality Assessment Tool for Quantitative Studies (QATQS).The meta-analysis of three studies was conducted. 

**Result(s):** 
A total of 15 studies with 390 participants (aged: 3-16 years) were included. The interaction between psychosocial functioning and EAAT was investigated in most studies. Improvement was reported in the following domains: socialization, engagement, maladaptive behaviors, and shorter reaction time in problem-solving situations after EAAT. The meta-analysis revealed no statistically significant differences for the investigated effects. 

**Conclusion(s):** 
Despite the need for further, more standardized research, the results of the studies included in this review allow us to conclude that EAAT may be a useful form of therapy in children with ASD. Copyright &copy; 2018 The Authors
AN  - 2001278551
AU  - Trzmiel,
AU  - T.
AU  - Purandare,
AU  - B.
AU  - Michalak,
AU  - M.
AU  - Zasadzka,
AU  - E.
AU  - Pawlaczyk,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ctim.2018.11.004
L1  - internal-pdf://4137680095/Trzmiel-2019-Equine assisted activities and th.pdf
PY  - 2019
SP  - 104-113
T2  - Complementary Therapies in Medicine
TI  - Equine assisted activities and therapies in children with autism spectrum disorder: A systematic review and a meta-analysis
UR  - http://www.elsevier.com/wps/find/journaldescription.cws_home/623020/authorinstructions
UR  - https://ac.els-cdn.com/S0965229918308331/1-s2.0-S0965229918308331-main.pdf?_tid=cd40a2f9-480b-406b-95fa-36af4e3fef86&amp;acdnat=1547554384_07df416bbf48d7367cc6f3064ae796f8
VL  - 42
ER  -
TY  - JOUR
AB  - In this comprehensive systematic review and meta-analysis of group design studies of nonpharmacological early interventions designed for young children with autism spectrum disorder (ASD), we report summary effects across 7 early intervention types (behavioral, developmental, naturalistic developmental behavioral intervention [NDBI], TEACCH, sensory-based, animal-assisted, and technology-based), and 15 outcome categories indexing core and related ASD symptoms. A total of 1,615 effect sizes were gathered from 130 independent participant samples. A total of 6,240 participants, who ranged in age from 0-8 years, are represented across the studies. We synthesized effects within intervention and outcome type using a robust variance estimation approach to account for the nesting of effect sizes within studies. We also tracked study quality indicators, and report an additional set of summary effect sizes that restrict included studies to those meeting prespecified quality indicators. Finally, we conducted moderator analyses to evaluate whether summary effects across intervention types were larger for proximal as compared with distal effects, and for context-bound as compared to generalized effects. We found that when study quality indicators were not taken into account, significant positive effects were found for behavioral, developmental, and NDBI intervention types. When effect size estimation was limited to studies with randomized controlled trial (RCT) designs, evidence of positive summary effects existed only for developmental and NDBI intervention types. This was also the case when outcomes measured by parent report were excluded. Finally, when effect estimation was limited to RCT designs and to outcomes for which there was no risk of detection bias, no intervention types showed significant effects on any outcome. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
AD  - Sandbank, Micheal. Department of Special Education.Bottema-Beutel, Kristen. Lynch School of Education and Human Development.Crowley, Shannon. Lynch School of Education and Human Development.Cassidy, Margaret. College of Arts and Sciences.Dunham, Kacie. Vanderbilt Brain Institute.Feldman, Jacob I. Department of Speech and Hearing Sciences.Crank, Jenna. Department of Special Education.Albarran, Susanne A. Department of Special Education.Raj, Sweeya. College of Arts and Sciences.Mahbub, Prachy. Department of Neuroscience and Behavior.Woynaroski, Tiffany G. Department of Speech and Hearing Sciences.
AN  - 31763860
AU  - Sandbank,
AU  - M.
AU  - Bottema-Beutel,
AU  - K.
AU  - Crowley,
AU  - S.
AU  - Cassidy,
AU  - M.
AU  - Dunham,
AU  - K.
AU  - Feldman,
AU  - J.
AU  - I.
AU  - Crank,
AU  - J.
AU  - Albarran,
AU  - S.
AU  - A.
AU  - Raj,
AU  - S.
AU  - Mahbub,
AU  - P.
AU  - Woynaroski,
AU  - T.
AU  - G.
DA  - Nov 25
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1037/bul0000215
DP  - Ovid Technologies
J2  - Psychol Bull
L1  - internal-pdf://4229738715/Sandbank-2019.pdf
LA  - English
N1  - Using Smart Source ParsingNovSandbank, MichealBottema-Beutel, KristenCrowley, ShannonCassidy, MargaretDunham, KacieFeldman, Jacob ICrank, JennaAlbarran, Susanne ARaj, SweeyaMahbub, PrachyWoynaroski, Tiffany G
PY  - 2019
SP  - 25
T2  - Psychological Bulletin
TI  - Project AIM: Autism intervention meta-analysis for studies of young children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31763860
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31763860&amp;id=doi:10.1037%2Fbul0000215&amp;issn=0033-2909&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2019&amp;title=Psychological+Bulletin&amp;atitle=Project+AIM%3A+Autism+intervention+meta-analysis+for+studies+of+young+children.&amp;aulast=Sandbank&amp;pid=%3Cauthor%3ESandbank+M%3C%2Fauthor%3E%3CAN%3E31763860%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 25
ER  -
TY  - JOUR
AB  - **Objective: **
eHealth interventions have been shown to be effective in improving anxiety among the general population. Despite the effectiveness of eHealth interventions for perinatal depression, a recent review reported mixed results for perinatal anxiety. The review, however, was not focused on anxiety, and studies with various designs were included. The aim of this systematic review is to summarize the evidence specific to anxiety and to conduct a meta-analysis to examine the effectiveness of eHealth interventions in reducing perinatal anxiety. 

**Data Sources: **
MEDLINE, CINAHL, EMBASE, and PsycINFO were searched beginning with the date that the databases were available through March 2018 using keywords such as perinatal period, web-based interventions, and anxiety. 

**Study Selection: **
Randomized controlled trials that were conducted during the perinatal period, examined the effectiveness of an eHealth mental health intervention, measured anxiety symptoms or disorders as a primary or secondary outcome, provided data on anxiety levels both pre-intervention and post-intervention, had a comparison group, and were published in English were included. A total of 770 articles were retrieved, and the full texts of 64 articles were reviewed. Five studies met the inclusion criteria, 4 of which fulfilled the quality criteria and were included in the meta-analysis. 

**Data Extraction: **
Data were extracted using a data extraction form developed for this study. The Cochrane Collaboration&#039;s Review Manager software was used to conduct the meta-analysis. 

**Results: **
The test for heterogeneity (I2 = 0%; P = .80) suggested a homogeneous sample. The meta-analysis for the total effect size showed that at post-intervention, the eHealth group had significantly lower anxiety scores than the control group, with a standardized mean difference of -0.41 (95% CI, -0.71 to -0.11; P = .007). 

**Conclusions: **
eHealth interventions are promising in improving perinatal anxiety. The content of these interventions should account for common comorbid mental health conditions during the perinatal period and provide opportunities to tailor further treatment if necessary.
AN  - 30688418
AU  - Bayrampour,
AU  - H.
AU  - Trieu,
AU  - J.
AU  - Tharmaratnam,
AU  - T.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.4088/JCP.18r12386
L1  - internal-pdf://3139507982/Bayrampour-2019-Effectiveness of eHealth Inter.pdf
PY  - 2019
SP  - 22
T2  - Journal of Clinical Psychiatry
TI  - Effectiveness of eHealth Interventions to Reduce Perinatal Anxiety: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30688418
UR  - https://www.psychiatrist.com/JCP/article/Pages/2019/v80/18r12386.aspx
VL  - 80
ER  -
TY  - JOUR
AB  - **Background**
Psychological therapies for parents of children and adolescents with chronic illness aim to improve parenting behavior and mental health, child functioning (behavior/disability, mental health, and medical symptoms), and family functioning.

This is an updated version of the original Cochrane Review (2012) which was first updated in 2015.

**Objectives**
To evaluate the efficacy and adverse events of psychological therapies for parents of children and adolescents with a chronic illness.

**Search methods**
We searched CENTRAL, MEDLINE, Embase, PsycINFO, and trials registries for studies published up to July 2018.

**Selection criteria**
Included studies were randomized controlled trials (RCTs) of psychological interventions for parents of children and adolescents with a chronic illness. In this update we included studies with more than 20 participants per arm. In this update, we included interventions that combined psychological and pharmacological treatments. We included comparison groups that received either non‐psychological treatment (e.g. psychoeducation), treatment as usual (e.g. standard medical care without added psychological therapy), or wait‐list.

**Data collection and analysis**
We extracted study characteristics and outcomes post‐treatment and at first available follow‐up. Primary outcomes were parenting behavior and parent mental health. Secondary outcomes were child behavior/disability, child mental health, child medical symptoms, and family functioning. We pooled data using the standardized mean difference (SMD) and a random‐effects model, and evaluated outcomes by medical condition and by therapy type. We assessed risk of bias per Cochrane guidance and quality of evidence using GRADE.

**Main results**
We added 21 new studies. We removed 23 studies from the previous update that no longer met our inclusion criteria. There are now 44 RCTs, including 4697 participants post‐treatment. Studies included children with asthma (4), cancer (7), chronic pain (13), diabetes (15), inflammatory bowel disease (2), skin diseases (1), and traumatic brain injury (3). Therapy types included cognitive‐behavioural therapy (CBT; 21), family therapy (4), motivational interviewing (3), multisystemic therapy (4), and problem‐solving therapy (PST; 12). We rated risk of bias as low or unclear for most domains, except selective reporting bias, which we rated high for 19 studies due to incomplete outcome reporting. Evidence quality ranged from very low to moderate. We downgraded evidence due to high heterogeneity, imprecision, and publication bias.

Evaluation of parent outcomes by medical condition

Psychological therapies may improve parenting behavior (e.g. maladaptive or solicitous behaviors; lower scores are better) in children with cancer post‐treatment and follow‐up (SMD &minus;0.28, 95% confidence interval (CI) &minus;0.43 to &minus;0.13; participants = 664; studies = 3; SMD &minus;0.21, 95% CI &minus;0.37 to &minus;0.05; participants = 625; studies = 3; I2 = 0%, respectively, low‐quality evidence), chronic pain post‐treatment and follow‐up (SMD &minus;0.29, 95% CI &minus;0.47 to &minus;0.10; participants = 755; studies = 6; SMD &minus;0.35, 95% CI &minus;0.50 to &minus;0.20; participants = 678; studies = 5, respectively, moderate‐quality evidence), diabetes post‐treatment (SMD &minus;1.39, 95% CI &minus;2.41 to &minus;0.38; participants = 338; studies = 5, very low‐quality evidence), and traumatic brain injury post‐treatment (SMD &minus;0.74, 95% CI &minus;1.25 to &minus;0.22; participants = 254; studies = 3, very low‐quality evidence). For the remaining analyses data were insufficient to evaluate the effect of treatment.

Psychological therapies may improve parent mental health (e.g. depression, anxiety, lower scores are better) in children with cancer post‐treatment and follow‐up (SMD &minus;0.21, 95% CI &minus;0.35 to &minus;0.08; participants = 836, studies = 6, high‐quality evidence; SMD &minus;0.23, 95% CI &minus;0.39 to &minus;0.08; participants = 667; studies = 4, moderate‐quality evidence, respectively), and chronic pain post‐treatment and follow‐up (SMD &minus;0.24, 95% CI &minus;0.42 to &minus;0.06; participants = 490; studies = 3; SMD &minus;0.20, 95% CI &minus;0.38 to &minus;0.02; participants = 482; studies = 3, respectively, low‐quality evidence). Parent mental health did not improve in studies of children with diabetes post‐treatment (SMD &minus;0.24, 95% CI &minus;0.90 to 0.42; participants = 211; studies = 3, very low‐quality evidence). For the remaining analyses, data were insufficient to evaluate the effect of treatment on parent mental health.

Evaluation of parent outcomes by psychological therapy type

CBT may improve parenting behavior post‐treatment (SMD &minus;0.45, 95% CI &minus;0.68 to &minus;0.21; participants = 1040; studies = 9, low‐quality evidence), and follow‐up (SMD &minus;0.26, 95% CI &minus;0.42 to &minus;0.11; participants = 743; studies = 6, moderate‐quality evidence). We did not find evidence for a beneficial effect for CBT on parent mental health at post‐treatment or follow‐up (SMD &minus;0.19, 95% CI &minus;0.41 to 0.03; participants = 811; studies = 8; SMD &minus;0.07, 95% CI &minus;0.34 to 0.20; participants = 592; studies = 5; respectively, very low‐quality evidence). PST may improve parenting behavior post‐treatment and follow‐up (SMD &minus;0.39, 95% CI &minus;0.64 to &minus;0.13; participants = 947; studies = 7, low‐quality evidence; SMD &minus;0.54, 95% CI &minus;0.94 to &minus;0.14; participants = 852; studies = 6, very low‐quality evidence, respectively), and parent mental health post‐treatment and follow‐up (SMD &minus;0.30, 95% CI &minus;0.45 to &minus;0.15; participants = 891; studies = 6; SMD &minus;0.21, 95% CI &minus;0.35 to &minus;0.07; participants = 800; studies = 5, respectively, moderate‐quality evidence). For the remaining analyses, data were insufficient to evaluate the effect of treatment on parent outcomes.

Adverse events

We could not evaluate treatment safety because most studies (32) did not report on whether adverse events occurred during the study period. In six studies, the authors reported that no adverse events occurred. The remaining six studies reported adverse events and none were attributed to psychological therapy. We rated the quality of evidence for adverse events as moderate.

**Authors&#039; conclusions**
Psychological therapy may improve parenting behavior among parents of children with cancer, chronic pain, diabetes, and traumatic brain injury. We also found beneficial effects of psychological therapy may also improve parent mental health among parents of children with cancer and chronic pain. CBT and PST may improve parenting behavior. PST may also improve parent mental health. However, the quality of evidence is generally low and there are insufficient data to evaluate most outcomes. Our findings could change as new studies are conducted.
AN  - CD009660
AU  - Law,
AU  - E.
AU  - Fisher,
AU  - E.
AU  - Eccleston,
AU  - C.
AU  - Palermo,
AU  - T.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD009660.pub4
KW  - Adolescent
KW  - Child
KW  - Child, Preschool
KW  - Chronic Disease [*psychology]
KW  - Cognitive Behavioral Therapy
KW  - Family Relations
KW  - Family Therapy
KW  - Humans
KW  - Infant
KW  - Motivational Interviewing
KW  - Parenting [psychology]
KW  - Parents [*psychology]
KW  - Problem Solving
KW  - Psychotherapy [*methods]
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://3928305855/Law_et_al-2019-Cochrane_Database_of_Systematic.pdf
N1  - [Pain, Palliative and Supportive Care]
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological interventions for parents of children and adolescents with chronic illness
UR  - https://doi.org//10.1002/14651858.CD009660.pub4
ER  -
TY  - JOUR
AB  - Bystander programmes increase bystander intervention but no effect on perpetrating sexual assault.
Bystander sexual assault prevention programs have beneficial effects on bystander intervention but there is no evidence of effects on sexual assault perpetration. Effects on knowledge and attitudes are inconsistent across outcomes. 

**What is this review about?**
Sexual assault is a significant problem among adolescents and college students across the world. One promising strategy for preventing these assaults is the implementation of bystander sexual assault prevention programs, which encourage young people to intervene when witnessing incidents or warning signs of sexual assault. This review examines the effects bystander programs have on knowledge and attitudes concerning sexual assault and bystander behavior, bystander intervention when witnessing sexual assault or its warning signs, and participants&rsquo; rates of perpetration of sexual assault.

**What is the aim of this review?**
This Campbell systematic review examines the effects of bystander programs on knowledge and attitudes concerning sexual assault and bystander intervention,bystander intervention when witnessing sexual assault or its warning signs, and the perpetration of sexual assault. The review summarizes evidence from 27 high-quality studies, including 21 randomized controlled trials. 

**What are the main findings of this review? What studies are included?**
This review includes studies that evaluate the effects of bystander programs for young people on (1)knowledge and attitudes concerning sexual assault and bystander intervention, (2) bystander intervention behavior when witnessing sexual assault or its warning signs, and (3) perpetration of sexual assault. Twenty-seven studies met the inclusion criteria. These included studies span the period from 1997 to 2017 and were primarily conducted in the USA (one study was conducted in Canada and one in India). Twenty-one of the studies were randomized controlled trials and six were high quality quasi-experimental studies. 

**Do bystander programs have an effect on knowledge/attitudes, on bystander intervention, or on sexual assault perpetration?**
Bystander programs have an effect on knowledge and attitudes for some outcomes. The most pronounced beneficial effects are on rape myth acceptance and bystander efficacy outcomes. There are also delayed effects (i.e., one to four months after the intervention) on taking responsibility for intervening/acting, knowing strategies for intervening, and intentions to intervene outcomes. There is little or no evidence of effects on gender attitudes, victim empathy, date rape attitudes,and on noticing sexual assault outcomes.Bystander programs have a beneficial effect on bystander intervention. There is no evidence that bystander programs have an effect on participants&rsquo; rates of sexual assault perpetration.

**What do the findings of this review mean?** 
The United States 2013 Campus Sexual Violence Elimination (SaVE) Act requires post-secondary educational institutions participating in Title IX financial aid programs to provide incoming collegestudents with sexual violence prevention programming that includes a component on bystander intervention. Bystander programs have a significant effect on bystander intervention. But there is no evidence that these programs have an effect on rates of sexual assault perpetration. This suggests that bystander programs may be appropriate for targeting the behavior of potential bystanders but may not be appropriate for targeting the behavior of potential perpetrators. Beneficial effects of bystander programs on bystander intervention were diminished by six months post-intervention. Thus, booster sessions may be needed to yield any sustained effects.There are still important questions worth further exploration. Namely, more research is needed to investigate the underlying causal mechanisms of program effects on bystander behavior (e.g., to model relationships between specific knowledge/attitude effects and bystander intervention effects), and to identify the most effective types of bystander programs (e.g., using randomized controlled trials to compare the effects of two alternate program models). Additionally, more research is needed in contexts outside of the USA so that researchers can better understand the role of bystander programs across the world.

**How up-to-date is this review?**
The review authors searched for studies up to June 2017. This Campbell systematic review was submitted in October 2017, revised in October 2018, and published January 2019.
AU  - Kettrey,
AU  - H.
AU  - H.
AU  - Marx,
AU  - R.
AU  - A.
AU  - Tanner-Smith,
AU  - E.
AU  - E.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.4073/csr.2019.1
L1  - internal-pdf://1281127888/Hensman Kettrey-2019-Effects of bystander prog.pdf
PY  - 2019
T2  - Campbell Systematic Reviews
TI  - Effects of bystander programs on the prevention of sexuael assault among adolescents and college students
VL  - 15
ER  -
TY  - JOUR
AB  - Adolescents affected by overweight or obesity report similar quality of life to adolescents with cancer. While weight management is important for physiological outcomes, it is unclear whether weight management improves quality of life in this age group. This meta-analysis assessed the impact of multicomponent weight management interventions on quality of life in adolescents affected by overweight or obesity. 

Ovid PsycINFO, Ovid Medline, Ovid Embase, Cochrane Library, Scopus and CINAHL Plus databases were searched up to July 2017. Eight eligible studies were randomized controlled trials of multicomponent weight management interventions for adolescents (10 to 19 years) affected by overweight or obesity, with quality of life and weight measurements. Meta-analyses determined a positive effect on quality of life (mean difference 0.20 [0.11, 0.29]; p &lt; 0.01) and weight (mean difference 0.30 [0.12, 0.47]; p &lt; 0.01) following intervention.

There was no correlation between weight loss and improvements in quality of life (R&lt;sup&gt;2&lt;/sup&gt; = 0.103). Rather than weight loss, intervention factors such as parental involvement, group settings and a focus on psychosocial well-being appeared linked to improvements in quality of life. The reduced quality of life reported by this group may be due to social consequences of obesity, rather than actual weight.
AN  - 30358046
AU  - Murray,
AU  - M.
AU  - Pearson,
AU  - J.
AU  - L.
AU  - Dordevic,
AU  - A.
AU  - L.
AU  - Bonham,
AU  - M.
AU  - P.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/obr.12774
L1  - internal-pdf://0509417936/Murray-2019-The impact of multicomponent weigh.pdf
PY  - 2019
SP  - 278-289
T2  - Obesity Reviews
TI  - The impact of multicomponent weight management interventions on quality of life in adolescents affected by overweight or obesity: a meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30358046
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/obr.12774
VL  - 20
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Suicide is a major public health problem. Educational interventions for preventing suicidal behaviour are widely used, although little is known regarding the collective effectiveness of these interventions. 

**AIM:** 
We evaluated the existing evidence for the effectiveness of education interventions in the prevention of suicidal behaviour. 

**METHODS:** 
In this systematic review and meta-analysis, we searched multiple databases using terms related to suicide prevention. The articles were reviewed by two independent reviewers, and the quality of evidence was rated according to Grading of Recommendations Assessment, Development and Evaluation (GRADE) criteria. Data from individual studies were combined in meta-analyses. 

**RESULTS:** 
We identified 41 studies evaluating two different types of interventions: school-based education interventions and gatekeeper training. Education interventions showed significant gains in terms of knowledge and attitudes, though the effects seem to vary depending on subjects&#039; personal characteristics. School-based education interventions significantly reduced suicidal ideation and suicide attempts in youths. Gatekeeper training showed no significant effect on suicide attempts or gatekeeper skills, though the quality of evidence for the estimate, according to GRADE criteria, was rated as very low. 

**CONCLUSION:** 
The results of this study indicate that school-based education interventions are effective in preventing suicidal ideation and suicide attempts. In clinical practice, as well as in research, the development and implementation of educational interventions should focus on participants&#039; individual characteristics.
AN  - 31159627
AU  - Pistone,
AU  - I.
AU  - Beckman,
AU  - U.
AU  - Eriksson,
AU  - E.
AU  - Lagerlof,
AU  - H.
AU  - Sager,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0020764019852655
L1  - internal-pdf://3122898128/Pistone-2019-The effects of educational interv.pdf
PY  - 2019
SP  - 20764019852655
T2  - International Journal of Social Psychiatry
TI  - The effects of educational interventions on suicide: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31159627
ER  -
TY  - JOUR
AB  - **Background**
Bipolar disorder is a severe and common mental disorder where patients experience recurrent symptoms of elevated or irritable mood, depression, or a combination of both. Treatment is usually with psychiatric medication, including mood stabilisers, antidepressants and antipsychotics. Valproate is an effective maintenance treatment for bipolar disorder. However, evidence assessing the efficacy of valproate in the treatment of acute mania is less robust, especially when comparing it to some of the newer antipsychotic agents. This review is an update of a previous Cochrane Review (last published 2003) on the role of valproate in acute mania.

**Objectives**
To assess the efficacy and tolerability of valproate for acute manic episodes in bipolar disorder compared to placebo, alternative pharmacological treatments, or a combination pharmacological treatments, as measured by the treatment of symptoms on specific rating scales for individual episodes in paediatric, adolescent and adult populations.

**Search methods**
We searched Ovid MEDLINE (1950‐ ), Embase (1974‐ ), PsycINFO (1967‐ ) and the Cochrane Central Register of Controlled Trials (CENTRAL) to 28 September 2018. We had also conducted an earlier search of these databases in the Cochrane Common Mental Disorders Controlled Trials Register (CCMDCTR) (all years to 6 June 2016). We also searched the World Health Organization (WHO) trials portal (ICTRP) and clinicaltrials.gov in September 2018, to identify any additional unpublished or ongoing studies.

**Selection criteria**
Single‐ and double‐blind, randomised controlled trials comparing valproate with placebo, alternative antimanic treatments, or a combination of pharmacological treatments. We also considered studies where valproate was used as an adjunctive treatment in combination with another agent separately from studies where it was used in monotherapy. We included male and female patients of all ages and ethnicity with bipolar disorder.

**Data collection and analysis**
Two review authors independently performed data extraction and methodological quality assessment. For analysis, we used the odds ratio (OR) for binary efficacy outcomes and the mean difference (MD) or standardised mean difference (SMD) for continuously distributed outcomes.Main resultsTwenty‐five trials (3252 participants) compared valproate with either placebo or alternative antimanic treatments to alleviate the symptoms of acute mania. For efficacy, our primary outcome was response rate. For tolerability, our primary outcome was the number of participants with any adverse effect. This meta‐analysis included studies focusing on children, adolescents, as well as adults with a range of severity of manic symptoms. The majority of studies focused on adult men and women (aged 18 and above), were conducted in inpatient settings and completed in the US. Five studies in this review focused on children and adolescents (aged 18 and under) so that the review covers an age range from 3 ‐ 82 years. Seven studies contained outpatient participants in some form. Nine studies included data that has been collected outside the US, namely Iran (4 studies), India (3 studies), China (1 study), or across several international countries (1 study).In adults, high‐quality evidence found that valproate induces a slightly higher response compared to placebo (45% vs 29%, OR 2.05, 95% CI 1.32 to 3.20; 4 studies, 869 participants). Moderate‐quality evidence found there was probably little or no difference in response rates between valproate and lithium (56% vs 62%, OR 0.80, 95% CI 0.48 to 1.35; 3 studies, 356 participants). In adults, low‐quality evidence found there may be little or no difference in response rate between valproate and olanzapine (38% vs 44%, OR 0.77, 95% CI 0.48 to 1.25; 2 studies, 667 participants).In the children and adolescent population, the evidence regarding any difference in response rates between valproate and placebo was uncertain (23% vs 22%, OR 1.11, 95% CI 0.51 to 2.38; 1 study, 151 participants, very low‐quality evidence). Low‐quality evidence found that the response rate of participants receiving valproate may be lower compared to risperidone (23% vs 66%, OR 0.16, 95% CI 0.08 to 0.29; 1 study, 197 participants). The evidence regarding any difference in response rates between valproate and lithium was uncertain (23% vs 34%, OR 0.57, 95% CI 0.31 to 1.07; 1 study, 197 participants, very low‐quality evidence).In terms of tolerability in adults, moderate‐quality evidence found that there are probably more participants receiving valproate who experienced any adverse events compared to placebo (83% vs 75%, OR 1.63, 95% CI 1.13 to 2.36; 3 studies, 745 participants). Low‐quality evidence found there may be little or no difference in tolerability between valproate and lithium (78% vs 86%, OR 0.61, 95% CI 0.25 to 1.50; 2 studies, 164 participants). We did not obtain primary tolerability outcome data on the olanzapine comparison.Within the children and adolescent population, the evidence regarding any difference between valproate or placebo was uncertain (67% vs 60%, OR 1.39, 95% CI 0.71 to 2.71; 1 study, 150 participants, very low‐quality evidence). We did not obtain primary tolerability outcome data on the lithium or risperidone comparisons.

**Authors&#039; conclusions**
There is evidence that valproate is an efficacious treatment for acute mania in adults when compared to placebo. By contrast, there is no evidence of a difference in efficacy between valproate and placebo for children and adolescents. Valproate may be less efficacious than olanzapine in adults, and may also be inferior to risperidone as a monotherapy treatment for paediatric mania. Generally, there is uncertain evidence regarding whether valproate causes more or less side effects than the other main antimanic therapies. However, evidence suggests that valproate causes less weight gain and sedation than olanzapine.
AU  - Jochim,
AU  - J.;
AU  - P
AU  - Rifkin‐Zybutz,
AU  - R.;
AU  - Geddes,
AU  - J.;
AU  - Cipriani,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD004052.pub2
L1  - internal-pdf://2278611702/Jochim_et_al-2019-Cochrane_Database_of_Systema.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Valproate for acute mania
ER  -
TY  - JOUR
AB  - **Introduction:**
To compare common side effects of mood stabilizers (MSs) and antipsychotics in pediatric and adult bipolar disorder (BD). 

**Area covered:**
 MEDLINE, EMBASE, PsycINFO was searched for randomized, double-blind, placebo-controlled trials (RCTs) in the treatment of pediatric and adult BD. Twelve RCTs for pediatric patients and 30 for adult patients were included. The risk for the discontinuation due to adverse events, &gt;= 7% weight gain, somnolence, akathisia, nausea and vomiting from a medication relative to placebo was estimated with absolute risk increase and the number needed to harm. The relative risk of these measures in pediatric and adult patients was compared. 

**Expert opinion:**
Overall, the relative risk for &gt;= 7% weight gain, somnolence, nausea, or vomiting was higher, and akathisia was lower in pediatric patients than in adults. The magnitude of difference among MSs and antipsychotics and between pediatrics and adults varied widely. The risk for pediatric patients could be underestimated because in most pediatric studies, doses of studied medications were lower and flexibly-dosed, and titration speeds were slower than in adult studies. Clinicians should pay attention to differences in study designs to understand the risk for common side effects when prescribing a medication for BD.
AN  - 31203678
AU  - Bai,
AU  - Y.
AU  - Liu,
AU  - T.
AU  - Xu,
AU  - A.
AU  - Yang,
AU  - H.
AU  - Gao,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/14740338.2019.1632832
L1  - internal-pdf://1297586284/Bai-2019-Comparison of common side effects fro.pdf
PY  - 2019
SP  - 15
T2  - Expert Opinion on Drug Safety
TI  - Comparison of common side effects from mood stabilizers and antipsychotics between pediatric and adult patients with bipolar disorder: a systematic review of randomized, double-blind, placebo-controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31203678
UR  - https://www.tandfonline.com/doi/full/10.1080/14740338.2019.1632832
VL  - 15
ER  -
TY  - JOUR
AB  - **Background**
Artificial formula can be manipulated to contain higher amounts of macro‐nutrients than maternal breast milk but breast milk confers important immuno‐nutritional advantages for preterm or low birth weight (LBW) infants.

**Objectives**
To determine the effect of feeding preterm or LBW infants with formula compared with maternal breast milk on growth and developmental outcomes.

**Search methods**
We used the standard strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL 2018, Issue 9), and Ovid MEDLINE, Ovid Embase, Ovid Maternity &amp; Infant Care Database, and CINAHL to October 2018. We searched clinical trials databases, conference proceedings, and the reference lists of retrieved articles.

**Selection criteria**
Randomised or quasi‐randomised controlled trials that compared feeding preterm or low birth weight infants with formula versus maternal breast milk.

**Data collection and analysis**
Two review authors planned independently to assess trial eligibility and risk of bias, and extract data. We planned to analyse treatment effects as described in the individual trials and report risk ratios and risk differences for dichotomous data, and mean differences for continuous data, with 95% confidence intervals. We planned to use a fixed‐effect model in meta‐analyses and to explore potential causes of heterogeneity in subgroup analyses. We planned to use the GRADE approach to assess the certainty of evidence.

**Main results**
We did not identify any eligible trials.

**Authors&#039; conclusions**
There are no trials of formula versus maternal breast milk for feeding preterm or low birth weight infants. Such trials are unlikely to be conducted because of the difficulty of allocating an alternative form of nutrition to an infant whose mother wishes to feed with her own breast milk. Maternal breast milk remains the default choice of enteral nutrition because observational studies, and meta‐analyses of trials comparing feeding with formula versus donor breast milk, suggest that feeding with breast milk has major immuno‐nutritional advantages for preterm or low birth weight infants.
AU  - Brown,
AU  - J.;
AU  - Walsh,
AU  - V.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.CD002972.pub3
L1  - internal-pdf://1598797613/Brown_et_al-2019-Cochrane_Database_of_Systemat.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Formula versus maternal breast milk for feeding preterm or low birth weight infants
ER  -
TY  - JOUR
AB  - **Background**
Antipsychotic medication is a commonly prescribed drug class in individuals with autism spectrum disorder (ASD). However, the safety of these agents has not been fully assessed.ObjectiveOur objective was to investigate the safety and tolerability profile of antipsychotics in individuals with ASD.

**Methods**
The Cochrane Library, MEDLINE, Embase and PsycINFO databases were searched up to January 2018. We included studies that reported adverse events (AEs) in participants with ASD taking first- or second-generation antipsychotic medication. The studies included in the analysis were randomized controlled trials (RCTs) and observational studies that were comparative or noncomparative and published as full text in the English language. The primary outcome of this review was AEs of any severity reported with antipsychotic use at any dose. Meta-analysis was performed on studies with child and adolescent participants to estimate the pooled prevalence of the overall AEs and the relative risk (RR) of AEs associated with antipsychotic use using a random-effects model. The Cochrane Collaboration tool and the modified Newcastle-Ottawa Scale (NOS) were used to assess the risk of bias of the included RCTs and observational studies, respectively.

**Results**
In total, 54 citations fulfilled the inclusion criteria, of which 40 were RCTs and 14 were observational studies; eight RCTs were included in the meta-analysis to estimate the RR of AEs associated with antipsychotic use and seven observational studies were included to estimate the pooled prevalence of AEs. The RR of AEs with antipsychotic treatment was 22% higher than with placebo (RR 1.22; 95% confidence interval [CI] 1.11-1.34; I-2=30.6%; p=0.184). The estimated pooled prevalence of AEs was 50.5% (95% CI 33-67). The most commonly reported AEs were increased appetite and weight gain, which were associated with discontinuation in many participants.

**Conclusion**
Antipsychotic-related AEs were common among patients with ASD. Further studies to investigate the implications of antipsychotic-related AEs on health and medication adherence are warranted. PROSPERO registration number: (CRD42018083632)
AN  - WOS:000472977200003
AU  - Alfageh,
AU  - B.
AU  - H.
AU  - Wang,
AU  - Z.
AU  - X.
AU  - Mongkhon,
AU  - P.
AU  - Besag,
AU  - F.
AU  - M.
AU  - C.
AU  - Alhawassi,
AU  - T.
AU  - M.
AU  - Brauer,
AU  - R.
AU  - Wong,
AU  - I.
AU  - C.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s40272-019-00333-x
L1  - internal-pdf://2335151877/Alfageh-2019-Safety and Tolerability of Antips.pdf
PY  - 2019
SP  - 153-167
T2  - Pediatric Drugs
TI  - Safety and Tolerability of Antipsychotic Medication in Individuals with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000472977200003
UR  - https://link.springer.com/article/10.1007%2Fs40272-019-00333-x
VL  - 21
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Adolescents aged 10-19 represent one sixth of the world&#039;s population and have a high burden of morbidity, particularly in low-resource settings. We know little about the potential of community-based peer facilitators to improve adolescent health in such contexts. 

**METHODS: **
We did a systematic review of peer-facilitated community-based interventions for adolescent health in low- and middle-income countries (LMICs). We searched databases for randomised controlled trials of interventions featuring peer education, counselling, activism, and/or outreach facilitated by young people aged 10-24. We included trials with outcomes across key areas of adolescent health: infectious and vaccine preventable diseases, undernutrition, HIV/AIDS, sexual and reproductive health, unintentional injuries, violence, physical disorders, mental disorders and substance use. We summarised evidence from these trials narratively. 

**PROSPERO registration: **CRD42016039190. 

**RESULTS:**
We found 20 studies (61,014 adolescents). Fourteen studies tested interventions linked to schools or colleges, and 12 had non-peer-facilitated components, e.g. health worker training. Four studies had HIV-related outcomes, but none reported reductions in HIV prevalence or incidence. Nine studies had clinical sexual and reproductive health outcomes, but only one reported a positive effect: a reduction in Herpes Simplex Virus-2 incidence. Three studies had violence-related outcomes, two of which reported reductions in physical violence by school staff and perpetration of physical violence by adolescents. Seven studies had mental health outcomes, four of which reported reductions in depressive symptoms. Finally, we found eight studies on substance use, four of which reported reductions in alcohol consumption and smoking or tobacco use. There were no studies on infectious and vaccine preventable diseases, undernutrition, or injuries. 

**CONCLUSIONS: **
There are few trials on the effects of peer-facilitated community-based interventions for adolescent health in LMICs. Existing trials have mixed results, with the most promising evidence supporting work with peer facilitators to improve adolescent mental health and reduce substance use and violence.
AN  - 30673732
AU  - Rose-Clarke,
AU  - K.
AU  - Bentley,
AU  - A.
AU  - Marston,
AU  - C.
AU  - Prost,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0210468
L1  - internal-pdf://1233368135/Rose-Clarke-2019-Peer-facilitated community-ba.pdf
PY  - 2019
SP  - e0210468
TI  - Peer-facilitated community-based interventions for adolescent health in low- and middle-income countries: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30673732
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0210468&amp;type=printable
VL  - 14
ER  -
TY  - JOUR
AB  - **Background**
To determine the impact of specialized treatments, relative to comparator treatments, upon the weight and psychological symptoms of anorexia nervosa (AN) at end-of-treatment (EOT) and follow-up.

**Methods**
Randomized controlled trials (RCTs) between January 1980 and December 2017 that reported the effects of at least two treatments on AN were screened. Weight and psychological symptoms were analyzed separately for each study. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed, and studies were assessed using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) criteria and Cochrane risk of bias tool.

**Results**
We identified 35 eligible RCTs, comprising data from 2524 patients. Meta-analyses revealed a significant treatment effect on weight outcomes at EOT [g = 0.16, 95% CI (0.05&ndash;0.28), p = 0.006], but not at follow-up [g = 0.11, 95% CI (&minus;0.04 to 0.27), p = 0.15]. There was no significant treatment effect on psychological outcomes at either EOT [g = &minus;0.03, 95% CI (&minus;0.14 to 0.08), p = 0.63], or follow-up [g = &minus;0.001, 95% CI (&minus;0.11 to 0.11), p = 0.98]. There was no strong evidence of publication bias or significant moderator effects for illness duration, mean age, year of publication, comparator group category, or risk of bias (all p values &gt; 0.05).

**Conclusions**
Current specialized treatments are more adept than comparator interventions at imparting change in weight-based AN symptoms at EOT, but not at follow-up. Specialized treatments confer no advantage over comparator interventions in terms of psychological symptoms. Future precision treatment efforts require a specific focus on the psychological symptoms of AN.
AN  - WOS:000458753100020
AU  - Murray,
AU  - S.
AU  - B.
AU  - Quintana,
AU  - D.
AU  - S.
AU  - Loeb,
AU  - K.
AU  - L.
AU  - Griffiths,
AU  - S.
AU  - Le
AU  - Grange,
AU  - D.
DB  - Rekoding IN SUM_lme.enl
DO  - https://doi.org/10.1017/S0033291718002088
L1  - internal-pdf://2204310887/Murray-2019-Treatment outcomes for anorexia ne.pdf
PY  - 2019
SP  - 701-704
T2  - Psychological Medicine
TI  - Treatment outcomes for anorexia nervosa: a systematic review and meta-analysis of randomized-controlled trials (vol 49, pg 535, 2018)
UR  - &lt;Go to ISI&gt;://WOS:000458753100020
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/A1A8EBE6E24F1B76848AA74A910F66D3/S0033291718003185a.pdf/div-class-title-treatment-outcomes-for-anorexia-nervosa-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials-corrigendum-div.pdf
VL  - 49
ER  -
TY  - JOUR
AB  - There is growing interest in the development of behavioral parent interventions targeting emotional and behavioral problems in children with autism spectrum disorders. Such interventions have potential to improve a number of child and parental well-being outcomes beyond disruptive child behavior. This systematic review and meta-analysis assesses evidence for the efficacy of behavioral parent interventions for disruptive and hyperactive child behavior in autism spectrum disorders, as well as parenting efficacy and stress. 

A total of 11 articles from nine randomized controlled trials were included. Sufficient data were available to calculate standardized mean difference and show favorable effects of behavioral parent interventions on parent-reported measures of child disruptive behavior (standardized mean difference = 0.67), hyperactivity (standardized mean difference = 0.31) and parent stress (standardized mean difference = 0.37); effects on parent efficacy are less clear (standardized mean difference = 0.39, p = 0.17). 

There were insufficient data to explore intervention effects on internalizing behavior in autism spectrum disorders, parenting behaviors, or observational and teacher-reported outcomes, providing important avenues for future research. This review adds to growing evidence of the efficacy of behavioral parent interventions for child behavior and parental well-being in autism spectrum disorders 

(Prospero: CRD42016033979).
AN  - 30818965
AU  - Tarver,
AU  - J.
AU  - Palmer,
AU  - M.
AU  - Webb,
AU  - S.
AU  - Scott,
AU  - S.
AU  - Slonims,
AU  - V.
AU  - Simonoff,
AU  - E.
AU  - Charman,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1362361319830042
L1  - internal-pdf://3463564311/Tarver-2019-Child and parent outcomes followin.pdf
PY  - 2019
SP  - 1362361319830042
T2  - Autism
TI  - Child and parent outcomes following parent interventions for child emotional and behavioral problems in autism spectrum disorders: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30818965
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
Suicide is a leading cause of death in young people, which may in part be because young people are notoriously poor help-seekers. Improving the identification of at-risk young people and connecting them to appropriate help is needed to prevent suicide in adolescents. The aim of this study is to examine the effectiveness of suicide prevention gatekeeper programs for parents and teachers, which are designed to improve their ability to recognise and respond to risks so that they may intervene before crisis occurs. 

**METHODS: **
Academic databases and reference lists were searched for gatekeeper training programs involving teachers and parents, and which aimed to prevent youth suicide, between journal inception and May 2018. Information directly reporting on suicide literacy (knowledge, confidence, attitudes) and/or gatekeeper behaviours (identification, referral) was extracted and a qualitative synthesis was conducted. 

**RESULTS:**
Thirteen studies fulfilled inclusion criteria. Significant moderate-to-large intervention effects were reported for suicide literacy outcomes among teachers and parents, with the largest gains among those with lowest baseline scores. No improvements in identification and referral behaviors among gatekeepers were noted. A need to improve evaluation research designs and outcome measurements was evident. 

**CONCLUSIONS: **
While gatekeeper programs lead to increased suicide literacy, there is little evidence for behavioural change. There is need to increase the reach and uptake of gatekeeper training by offering digital versions, which may lead to improved behavioural outcomes, and to employ targeted strategies to engage parents in this training as one of the most trusted sources of support for vulnerable youth.
AN  - 31054373
AU  - Torok,
AU  - M.
AU  - Calear,
AU  - A.
AU  - L.
AU  - Smart,
AU  - A.
AU  - Nicolopoulos,
AU  - A.
AU  - Wong,
AU  - Q.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.adolescence.2019.04.005
L1  - internal-pdf://1835964388/Torok-2019-Preventing adolescent suicide_ A sy.pdf
PY  - 2019
SP  - 100-112
T2  - Journal of Adolescence
TI  - Preventing adolescent suicide: A systematic review of the effectiveness and change mechanisms of suicide prevention gatekeeping training programs for teachers and parents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31054373
UR  - https://www.sciencedirect.com/science/article/pii/S0140197119300715?via%3Dihub
VL  - 73
ER  -
TY  - JOUR
AB  - **Background: **
Self-harm is a major public health problem. It is one of the best predictors of suicide in adolescents. Despite recent advances in the understanding of self-harm, poor treatment engagement remains a significant clinical obstacle. 

**Objectives: **
The purpose of thismeta-analysis is to update and extend previous research investigating treatment engagement with specific psychological treatments (SPT) vs. treatment as usual (TAU) in adolescents who self-harm.

**Methods: **
Data sources were identified by searching the Medline, PsychINFO, EMBASE, and PubMed databases as of October 2017. Randomized Controlled Trials (RCTs) comparing SPT and TAU in adolescents (through age 18 years) with self-harm were included. 

**Results: **
The results show that 12 RCTs investigating 1,255 young people were included in themeta-analysis. The proportion of adolescents not completing four ormore sessions in SPT was significantly lower (28.4%, 179/630) than TAU (45.9%, 287/625), RR = 0.64 (95% CI: 0.51 -0.79), p &lt; 0.0001. There were significantly more adolescents engaged with SPT than TAU. 

**Conclusions: **
Specific psychological treatments should be offered to adolescents with self-harm to maximize treatment engagement. Engaging adolescents with psychological treatment is necessary although not sufficient to achieve treatment goals.
AN  - WOS:000457632000001
AU  - Yuan,
AU  - S.
AU  - N.
AU  - V.
AU  - Kwok,
AU  - K.
AU  - H.
AU  - R.
AU  - Ougrin,
AU  - D.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.3389/fpsyg.2019.00104
L1  - internal-pdf://0040444739/Yuan-2019-Treatment Engagement in Specific Psy.pdf
PY  - 2019
SP  - 11
T2  - Frontiers in Psychology
TI  - Treatment Engagement in Specific Psychological Treatment vs. Treatment as Usual for Adolescents With Self-Harm: Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000457632000001
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/336273/pubmed-zip/.versions/1/.package-entries/fpsyg-10-00104/fpsyg-10-00104.pdf?sv=2015-12-11&amp;sr=b&amp;sig=0Bm%2BG3KVk2koQFummLnq70VUXdHfuPwzgnvIlW4kCVg%3D&amp;se=2019-03-06T13%3A06%3A59Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyg-10-00104.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **Background**
Preterm infants who are fed breast milk in comparison to infant formula have decreased morbidity such as necrotizing enterocolitis. Multi‐nutrient fortifiers used to increase the nutritional content of the breast milk are commonly derived from bovine milk. Human milk‐derived multi‐nutrient fortifier is now available, but it is not clear if it improves outcomes in preterm infants fed with breast milk.

**Objectives**
To determine whether the fortification of breast milk feeds with human milk‐derived fortifier in preterm infants reduces mortality, morbidity, and promotes growth and development compared to bovine milk‐derived fortifier.

**Search methods**
We searched the following databases for relevant trials in September 2018. Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library, Issue 9), electronic journal reference databases including MEDLINE (1980 to 20 September 2018), PREMEDLINE, Embase (1974 to 20 September 2018), CINAHL (1982 to 20 September 2018), biological abstracts in the database BIOSIS and conference abstracts from &#039;Proceedings First&#039; (from 1992 to 2011). We also included the following clinical trials registries for ongoing or recently completed trials: ClinicalTrials.gov (ClinicalTrials.gov), the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP; www.whoint/ictrp/search/en/) and the ISRCTN Registry (www.isrctn.com/), and abstracts of conferences: proceedings of Pediatric Academic Societies (American Pediatric Society, Society for Pediatric Research and European Society for Paediatric Research) from 1990 in the &#039;Pediatric Research&#039; journal and &#039;Abstracts online&#039; (2000 to 2017).

**Selection criteria**
We included randomized and quasi‐randomized controlled trials that compared preterm infants fed breast milk fortified with human milk‐derived fortifier versus those fed with breast milk fortified with bovine milk‐derived fortifier.

**Data collection and analysis**
The data were collected using the standard methods of Cochrane Neonatal. Two authors evaluated trial quality of the studies and extracted data. We reported dichotomous data using risk ratios (RRs), risk differences (RDs), number needed to treat (NNT) where applicable, and continuous data using mean differences (MDs). We assessed the quality of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.Main resultsOne randomized trial with 127 infants met the eligibility criteria and had low risk of bias. Human milk‐based fortifier did not decrease the risk of necrotizing enterocolitis in exclusively breast milk‐fed preterm infants (RR 0.95, 95% CI 0.2 to 4.54; 1 study, 125 infants, low certainty of evidence). Human milk‐derived fortifiers did not improve growth, decrease feeding intolerance, late‐onset sepsis, or death.

**Authors&#039; conclusions**
There is insufficient evidence evaluating human milk‐derived fortifier with bovine milk‐derived fortifier in exclusively breast milk‐fed preterm infants. Low‐certainty evidence from one study suggests that in exclusively breast milk‐fed preterm infants human milk‐derived fortifiers in comparison with bovine milk‐derived fortifier may not change the risk of necrotizing enterocolitis, mortality, feeding intolerance, infection, or improve growth. Well‐designed randomized controlled trials are needed to evaluate short‐term and long‐term outcomes.
AU  - Premkumar,
AU  - M.
AU  - H.
AU  - Pammi,
AU  - M.
AU  - Suresh,
AU  - G.
DA  - 07. Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.CD013145.pub2
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Human milk‐derived fortifier versus bovine milk‐derived fortifier for prevention of mortality and morbidity in preterm neonates
ER  -
TY  - JOUR
AB  - Despite decades of research on interventions for academically underachieving students, no clear answers have emerged. Synthesizing across existing intervention efforts can help in understanding not only the overall effectiveness for these interventions, but also the factors that may moderate such effectiveness. In the current study, we conducted a systematic review and meta-analysis to examine the effectiveness of interventions for academically underachieving students, exploring effects on achievement and psychosocial outcomes. Overall, findings from 53 studies revealed that interventions are moderately effective in improving achievement and psychosocial outcomes. Moderator analyses revealed that intervention effectiveness varied by grade level. Implications for research and practice are discussed, particularly the need for rigorous evaluations of well-designed interventions that consider the fit between students&#039; unique reasons for underachievement and the makeup of the intervention.
AD  - [Snyder, Kate E.] Hanover Coll, Hanover, NH USA. [Fong, Carlton J.] Texas State Univ, San Marcos, TX USA. [Painter, Jackson Kai] Univ Louisville, Louisville, KY 40292 USA. [Pittard, Caroline M.] Childrens Mercy Hosp, Kansas City, MO 64108 USA. [Barr, Sebastian M.] Cambridge Hlth Alliance, Cambridge, MA USA. [Barr, Sebastian M.] Harvard Med Sch, Boston, MA 02115 USA. [Patall, Erika A.] Univ Southern Calif, Los Angeles, CA 90007 USA.Snyder, KE (reprint author), Dept Psychol, Hanover, IN 47243 USA.snyder@hanover.edu
AN  - WOS:000501656900015
AU  - Snyder,
AU  - K.
AU  - E.
AU  - Fong,
AU  - C.
AU  - J.
AU  - Painter,
AU  - J.
AU  - K.
AU  - Pittard,
AU  - C.
AU  - M.
AU  - Barr,
AU  - S.
AU  - M.
AU  - Patall,
AU  - E.
AU  - A.
DA  - Nov
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1016/j.edurev.2019.100294
J2  - Educ. Res. Rev.
KW  - Underachievement
KW  - Gifted
KW  - Intervention
KW  - Meta-analysis
KW  - Systematic review
KW  - robust variance-estimation
KW  - small-sample adjustments
KW  - gifted students
KW  - school-students
KW  - hong-kong
KW  - achievement
KW  - science
KW  - elementary
KW  - model
KW  - identification
KW  - Education &amp; Educational Research
L1  - internal-pdf://1313648422/Snyder-2019-Interventions for academically und.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: JU4OMTimes Cited: 1Cited Reference Count: 115Snyder, Kate E. Fong, Carlton J. Painter, Jackson Kai Pittard, Caroline M. Barr, Sebastian M. Patall, Erika A.Esther Katz Rosen Fellowship from the American Psychological Foundation; Hollingworth Award from the National Association for Gifted ChildrenParts of this paper were presented at the annual meeting of the American Educational Research Association. This project has been funded through the Esther Katz Rosen Fellowship from the American Psychological Foundation and the Hollingworth Award from the National Association for Gifted Children.12Elsevier sci ltdOxford1878-0385
PY  - 2019
SP  - 22
T2  - Educational Research Review
TI  - Interventions for academically underachieving students: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000501656900015
UR  - https://pdf.sciencedirectassets.com/273542/1-s2.0-S1747938X19X00032/1-s2.0-S1747938X18306316/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEP3%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJIMEYCIQCRDGn2IwQnBCvhcMX9pDN%2BNUU%2BnGmWuL76GlEmJM6mKgIhAKrZi7FIPcBGLJwyI8kKy7yXsjoKjKgisBzyXpLkkEiYKr0DCOb%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEQAhoMMDU5MDAzNTQ2ODY1Igzm5NMX66PIa1DX9yIqkQNoVqqeMmczQ1i2V1Z31GrvAJkx%2Frk0aU8TfsWUK5m4JcyN%2BIuuHN0XGn5nv9hhHjEi7z7431l5k3EsC9mOKLwOqUVPhSIk7TZbU1gJAnYzyFCzYm1m%2BtjZGP5IbVbb8F%2BnmXyqITu%2FjHH4t3xD9SbOlLNXQUHa69C9r8GVmeZJ%2BXJz7AyS5sCqdaHNE%2B1pPn35hhxkhGm9pPn7zFH%2FCS0F%2BOxtY7MVuUKGxevE5Ow8yuuVxU2x3wfzwpq0A6e5h%2Bh%2FUCYZjFDcVo3gNQa0l%2FsuIYx1bitKVpI6iCUZ1lRdWyUrTGZR6JI1MsOI8vGexwiU7%2FT2unVWsRNaOkodBkVP%2FobSskItg1N2G%2BncadlFi6rxKNzd%2F%2F95hzg0YN9U%2FxVvYBYYhk3vmaAF6v6ObduWqvQ4R4DFHyNPfR0zQxOJOUxFeQsqVAh2LYc28gP2y%2Fw2Tamd2wlAA8xlD1ZeKHTPHiAk3zfpPCUmucYUvXkXFdK0OI8CK7RTfOjUY%2BNkI5EWF6Fl3anMgc06VnV3VwYDfTCLm9HzBTrqAWN3OM9nvckI9uCQTpjNZ6eTy0N1IIVApuqFVbCYsrOHunAacnIoY1FzBf6jBAsqHDaJOdnoh%2BnYJ4YP6LDlS9xGIwusgPVNOj06A7cO1NIkNFN2UQK8obmJyUb9ipvv9dALuHAXI6JWeq86EjqEHVm%2Fs8%2BWsJjM98CF2WTD7YfBexgfzj%2F3uZ7L7lZgrBL8pTIjVLwI%2FTLz%2BSx%2FnzEeN%2Fc0MDXHls5G2mxxiL1I5fbZMHgtE1MYsl%2BcCLICw7T5m2iQUNWcXTV6Z9UKMBZPn0fe6t3NNURhJa0idnNNz49KxI%2Fc%2FolB%2BX%2Bctw%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200320T062448Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYRNIN7Y4U%2F20200320%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=9b789953d6409774102de5a688b2a9ecb90d9a85e9450afa991816c9ab8a300b&amp;hash=9712c2bdcdfc28a021819a6849d503c8cedd152fd05eb03c4e35c4c291a920c2&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S1747938X18306316&amp;tid=spdf-f6329deb-9064-47c0-be54-3f287ab60f32&amp;sid=0e799d265196f84f6b6a8971d2fbb6d07c66gxrqb&amp;type=client
VL  - 28
ER  -
TY  - JOUR
AB  - Child maltreatment in the family context is a prevalent and pervasive phenomenon in many modern societies. The global perpetration of child abuse and neglect stands in stark contrast to its almost universal condemnation as exemplified in the United Nation&#039;s Convention on the Rights of the Child. Much work has been devoted to the task of prevention, yet a grand synthesis of the literature is missing. Focusing on two core elements of prevention, that is, antecedents for maltreatment and the effectiveness of (preventative) interventions, we performed an umbrella review of meta-analyses published between January 1, 2014, and December 17, 2018. Meta-analyses were systematically collected, assessed, and integrated following a uniform approach to allow their comparison across domains. From this analysis of thousands of studies including almost 1.5 million participants, the following risk factors were derived: parental experience of maltreatment in his or her own childhood (d = .47), low socioeconomic status of the family (d = .34), dependent and aggressive parental personality (d = .45), intimate partner violence (d = .41), and higher baseline autonomic nervous system activity (d = .24). The effect size for autonomic stress reactivity was not significant (d = -.10). The umbrella review of interventions to prevent or reduce child maltreatment showed modest intervention effectiveness (d = .23 for interventions targeting child abuse potential or families with self-reported maltreatment and d = .27 for officially reported child maltreatment cases). Despite numerous studies on child maltreatment, some large gaps in our knowledge of antecedents exist. Neurobiological antecedents should receive more research investment. Differential susceptibility theory may shed more light on questions aimed at breaking the intergenerational transmission of maltreatment and on the modest (preventive) intervention effects. In combination with family-based interaction-focused interventions, large-scale socioeconomic experiments such as cash transfer trials and experiments with vouchers to move to a lower-poverty area might be tested to prevent or reduce child maltreatment. Prevalence, antecedents, and preventive interventions of prenatal maltreatment deserve continuing scientific, clinical, and policy attention.
AD  - van IJzendoorn, Marinus H. Department of Psychology, Education, and Child Studies, Erasmus University Rotterdam, Rotterdam, The Netherlands.van IJzendoorn, Marinus H. Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK.Bakermans-Kranenburg, Marian J. Clinical Child and Family Studies, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.Coughlan, Barry. Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK.Reijman, Sophie. Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
AN  - 31667862
AU  - van,
AU  - IJzendoorn
AU  - M.
AU  - H.
AU  - Bakermans-Kranenburg,
AU  - M.
AU  - J.
AU  - Coughlan,
AU  - B.
AU  - Reijman,
AU  - S.
DA  - Oct 30
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.13147
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
L1  - internal-pdf://0278091971/IJzendoorn_et_al-2019-Journal_of_Child_Psychol.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingOctvan IJzendoorn, Marinus HBakermans-Kranenburg, Marian JCoughlan, BarryReijman, Sophie
PY  - 2019
SP  - 30
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Annual Research Review: Umbrella synthesis of meta-analyses on child maltreatment antecedents and interventions: differential susceptibility perspective on risk and resilience
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31667862
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31667862&amp;id=doi:10.1111%2Fjcpp.13147&amp;issn=0021-9630&amp;isbn=&amp;volume=&amp;issue=&amp;spage=jcpp&amp;pages=&amp;date=2019&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Annual+Research+Review%3A+Umbrella+synthesis+of+meta-analyses+on+child+maltreatment+antecedents+and+interventions%3A+differential+susceptibility+perspective+on+risk+and+resilience.&amp;aulast=van+IJzendoorn&amp;pid=%3Cauthor%3Evan+IJzendoorn+MH%3C%2Fauthor%3E%3CAN%3E31667862%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/jcpp.13147
VL  - 30
ER  -
TY  - JOUR
AB  - **Background**
Human milk banking has been available in many countries for the last three decades. The milk provided from milk banking is predominantly term breast milk, but some milk banks provide preterm breast milk. There are a number of differences between donor term and donor preterm human milk.

**Objectives**
To determine the effect of banked donor preterm milk compared with banked donor term milk regarding growth and developmental outcomes in very low birth weight infants (infants weighing less than 1500 grams).

**Search methods**
We used the standard search strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL 2018, Issue 7), MEDLINE via PubMed (1966 to 23 October 2018), Embase (1980 to 23 October 2018), and CINAHL (1982 to 23 October 2018). We also searched clinical trial databases, conference proceedings, and the reference lists of retrieved articles for randomised controlled trials and quasi‐randomised trials.

**Selection criteria**
Randomised and quasi‐randomised trials comparing banked donor preterm milk with banked donor term milk regarding growth and developmental outcomes in very low birth weight infants.

**Data collection and analysis**
We planned to perform assessment of methodology regarding blinding of randomisation, intervention and outcome measurements as well as completeness of follow‐up. We planned to evaluate treatment effect using a fixed‐effect model using relative risk (RR), relative risk reduction, risk difference (RD) and number needed to treat for an additional beneficial outcome (NNTB) or the number needed to treat for an additional harmful outcome (NNTH) for categorical data; and using mean, standard deviation and weighted mean difference (WMD) for continuous data. We planned to use the GRADE approach to assess the quality of evidence.

**Main results**
No studies met the inclusion criteria.

**Authors&#039; conclusions**
We found no evidence to support or refute the effect of banked donor preterm milk compared to banked term milk regarding growth and developmental outcomes in very low birth weight infants.
AU  - Dempsey,
AU  - E.
AU  - Miletin,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD007644.pub3
L1  - internal-pdf://2406729030/Dempsey-2019-Banked preterm versus banked term.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Banked preterm versus banked term human milk to promote growth and development in very low birth weight infants
ER  -
TY  - JOUR
AB  - Cognitive behavior therapy (CBT) is the most empirically supported therapy for childhood anxiety disorders (CADs) but has not reliably outperformed other credible interventions. The current study used meta-analysis to examine the frequency with which the most common treatment components are included in outcome studies and the relation of these components to symptom improvement. Seventy-five studies were identified that included youth with an anxiety disorder treated with CBT or a comparison condition. The protocols for the 111 CBT conditions generally consisted of 12, 1-h sessions delivered to the child with minimal parent inclusion. A greater amount of in-session exposure was related to significantly larger effect sizes between CBT and waitlist control across reporters (- 0.12 to - 0.15; P&#039;s &lt; .05) and from pre- to post-treatment for child report (- .06; P &lt; .01). Compared to treatments that omitted relaxation, treatments that included relaxation strategies were associated with significantly smaller pre- to post-treatment effect sizes across reporters (0.38 to 0.80; P&#039;s &lt; .05). The current study suggests that CBT protocols for CADs that emphasize in-session exposure and do not include relaxation have the potential to improve the efficacy and effectiveness of therapy. Dismantling studies directly testing these hypotheses are needed.
AD  - Whiteside, Stephen P H. Department of Psychiatry and Psychology, Mayo Clinic, Mayo Bldg West 11, 200 First St., SW, Rochester, MN, 55905, USA. whiteside.stephen@mayo.edu.Sim, Leslie A. Department of Psychiatry and Psychology, Mayo Clinic, Mayo Bldg West 11, 200 First St., SW, Rochester, MN, 55905, USA.Morrow, Allison S. Robert D. and Patricia E. Kern Center for Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.Farah, Wigdan H. Robert D. and Patricia E. Kern Center for Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.Hilliker, Daniel R. Department of Psychiatry and Psychology, Mayo Clinic, Mayo Bldg West 11, 200 First St., SW, Rochester, MN, 55905, USA.Murad, M Hassan. Robert D. and Patricia E. Kern Center for Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.Wang, Zhen. Robert D. and Patricia E. Kern Center for Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
AN  - 31628568
AU  - Whiteside,
AU  - S.
AU  - P.
AU  - H.
AU  - Sim,
AU  - L.
AU  - A.
AU  - Morrow,
AU  - A.
AU  - S.
AU  - Farah,
AU  - W.
AU  - H.
AU  - Hilliker,
AU  - D.
AU  - R.
AU  - Murad,
AU  - M.
AU  - H.
AU  - Wang,
AU  - Z.
DA  - Oct 18
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-019-00303-2
DP  - Ovid Technologies
J2  - Clin Child Fam Psychol Rev
L1  - internal-pdf://1154838349/Whiteside-2019.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingOctWhiteside, Stephen P HSim, Leslie AMorrow, Allison SFarah, Wigdan HHilliker, Daniel RMurad, M HassanWang, Zhen
PY  - 2019
SP  - 18
T2  - Clinical Child &amp; Family Psychology Review
TI  - A Meta-analysis to Guide the Enhancement of CBT for Childhood Anxiety: Exposure Over Anxiety Management
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31628568
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31628568&amp;id=doi:10.1007%2Fs10567-019-00303-2&amp;issn=1096-4037&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2019&amp;title=Clinical+Child+%26+Family+Psychology+Review&amp;atitle=A+Meta-analysis+to+Guide+the+Enhancement+of+CBT+for+Childhood+Anxiety%3A+Exposure+Over+Anxiety+Management.&amp;aulast=Whiteside&amp;pid=%3Cauthor%3EWhiteside+SPH%3C%2Fauthor%3E%3CAN%3E31628568%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10567-019-00303-2
UR  - https://link.springer.com/content/pdf/10.1007%2Fs10567-019-00303-2.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - **INTRODUCTION:**
In recent years, several non-specialist mediated interventions have been developed and tested to address problematic symptoms associated with autism. These can be implemented with a fraction of cost required for specialist delivered interventions. This review represents a robust evidence of clinical effectiveness of these interventions in improving the social, motor and communication deficits among children with autism.

**METHODS:** 
An electronic search was conducted in eight academic databases from their inception to 31st December 2018. A total of 31 randomized controlled trials were published post-2010 while only 2 were published prior to it. Outcomes pertaining to communication, social skills and caregiver-child relationship were meta-analyzed when reported in &gt; 2 studies.

**RESULTS:** 
A significant improvement was noted in child distress (SMD = 0.55), communication (SMD = 0.23), expressive language (SMD = 0.47), joint engagement (SMD = 0.63), motor skills (SMD = 0.25), parental distress (SMD = 0.33) parental self-efficacy (SMD = 0.42) parent-child relationship (SMD = 0.67) repetitive behaviors (SMD = 0.33), self-regulation (SMD = 0.54), social skills (SMD = 0.53) symptom severity (SMD = 0.44) and visual reception (SMD = 0.29).

**CONCLUSION:** 
Non-specialist mediated interventions for autism spectrum disorder demonstrate effectiveness across a range of outcomes for children with autism and their caregivers.
AD  - Naveed, Sadiq. Kansas University Medical Center, Kansas City, Kansas, United States of America.Waqas, Ahmed. Human Development Research Foundation, Rawalpindi, Pakistan.Amray, Afshan Naz. Dow University of Health Sciences, Karachi, Pakistan.Memon, Raheel Imtiaz. Henry Ford Allegiance Health, Jackson, MI, United States of America.Javed, Nisma. Services Institute of medical sciences, Lahore, Pakistan.Tahir, Muhammad Annas. Kingsbrook Jewish Medical Center, New York City, New York, United States of America.Ghozy, Sherief. Neurosurgery Department, El-Sheikh Zayed Specialized Hospital, Giza, Egypt.Jahan, Nusrat. Rush University Medical Center, Chicago, IL, United States of America.Khan, Anum Saeed. Westchester Medical Center-New York Medical College, Valhalla, NY, United States of America.Rahman, Atif. University of Liverpool, Liverpool, England, United Kingdom.
AN  - 31703073
AU  - Naveed,
AU  - S.
AU  - Waqas,
AU  - A.
AU  - Amray,
AU  - A.
AU  - N.
AU  - Memon,
AU  - R.
AU  - I.
AU  - Javed,
AU  - N.
AU  - Tahir,
AU  - M.
AU  - A.
AU  - Ghozy,
AU  - S.
AU  - Jahan,
AU  - N.
AU  - Khan,
AU  - A.
AU  - S.
AU  - Rahman,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0224362
DP  - Ovid Technologies
J2  - PLoS ONE
L1  - internal-pdf://0860508982/Naveed-2019-Implementation and effectiveness o.pdf
LA  - English
N1  - Naveed, SadiqWaqas, AhmedAmray, Afshan NazMemon, Raheel ImtiazJaved, NismaTahir, Muhammad AnnasGhozy, SheriefJahan, NusratKhan, Anum SaeedRahman, Atif
PY  - 2019
SP  - e0224362
T2  - PLoS ONE [Electronic Resource]
TI  - Implementation and effectiveness of non-specialist mediated interventions for children with Autism Spectrum Disorder: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31703073
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31703073&amp;id=doi:10.1371%2Fjournal.pone.0224362&amp;issn=1932-6203&amp;isbn=&amp;volume=14&amp;issue=11&amp;spage=e0224362&amp;pages=e0224362&amp;date=2019&amp;title=PLoS+ONE+%5BElectronic+Resource%5D&amp;atitle=Implementation+and+effectiveness+of+non-specialist+mediated+interventions+for+children+with+Autism+Spectrum+Disorder%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Naveed&amp;pid=%3Cauthor%3ENaveed+S%3C%2Fauthor%3E%3CAN%3E31703073%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839885/pdf/pone.0224362.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - **Background**
Parenteral nutrition solutions, artificial formulas, and human breast milk contain insufficient iodine to meet recommended intakes for preterm infants. Iodine deficiency may exacerbate transient hypothyroxinaemia in preterm infants and this may be associated with adverse neonatal and longer‐term outcomes.

**Objectives**
To assess the evidence from randomised controlled trials that dietary supplementation with iodine reduces mortality and morbidity in preterm infants.

**Search methods**
We used the standard search strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL 2018, Issue 1), Ovid MEDLINE, Ovid Embase, Ovid Maternity &amp; Infant Care Database, and CINAHL to February 2018. We searched clinical trials databases, conference proceedings, and the reference lists of retrieved articles for randomised controlled trials and quasi‐randomised trials.

**Selection criteria**
Randomised or quasi‐randomised controlled trials that compared supplementing enteral or parenteral feeds with iodine (as iodide salt) versus placebo or no supplementation in preterm infants.

**Data collection and analysis**
Two review authors independently assessed trial eligibility and risk of bias, and extracted data. We analysed treatment effects as described in the individual trials and reported risk ratios (RR) and risk differences for dichotomous data, and mean differences (MD) for continuous data, with 95% confidence intervals (CI). We used a fixed‐effect model in meta‐analyses and planned to explore potential causes of heterogeneity in sensitivity analyses. We used the GRADE approach to assess the quality of evidence.

**Main results**
Two randomised controlled trials fulfilled the eligibility criteria. Both trials used methods to limit bias including allocation concealment and blinding of clinicians and investigators to the allocated intervention. The trials enrolled 1394 infants. One trial recruited 1273 participants. Most participants were born very preterm (less than 32 weeks&#039; gestation) and about one‐third were extremely preterm (less than 28 weeks&#039; gestation). Analyses found no effect of iodine supplementation on mortality before hospital discharge (typical RR 1.01, 95% CI 0.72 to 1.42; typical RD 0.00, 95% CI ‐0.03 to 0.03; 2 studies, 1380 infants) or on neurodevelopmental assessments at two years post‐term (Bayley Scales of Infant and Toddler Development, Third Edition main domain composite scores: cognitive: MD &ndash;0.30, 95% CI &ndash;2.44 to 1.84; motor: MD 0.20, 95% CI &ndash;2.15 to 2.55; language: MD &ndash;0.10, 95% CI &ndash;2.50 to 2.30; 1 study, 1259 infants). There were no differences in the proportion of infants who died or had a composite score less than 85 in any main Bayley domain (RR 1.05, 95% CI 0.94 to 1.17; RD 0.02 95% CI ‐0.03 to 0.08; 1 study, 1259 infants), or had visual impairment (RR 0.63, 95% CI 0.28 to 1.45; RD ‐0.01 95% CI ‐0.03 to 0.01; 1 study, 1092 infants) or auditory impairment (RR 1.05, 95% CI 0.51 to 2.16; RD 0.00 95% CI ‐0.02 to 0.02 1 study, 1093 infants). Using GRADE methods, we assessed the evidence for the effects on mortality and neurodevelopment outcomes as high‐certainty.

**Authors&#039; conclusions**
The available trial data, predominantly from one large, high‐quality multicentre study published in 2017, do not show any evidence of beneficial effects of iodine supplementation for preterm infants. Given the high certainty of these estimates of effect, further trials of this intervention in this population are unlikely to be considered research priorities.
AU  - Walsh,
AU  - V.
AU  - Brown,
AU  - J.
AU  - V.
AU  - E.
AU  - McGuire,
AU  - W.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD005253.pub3
L1  - internal-pdf://0389689697/Walsh-2019-Iodine supplementation for the prev.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Iodine supplementation for the prevention of mortality and adverse neurodevelopmental outcomes in preterm infants
ER  -
TY  - JOUR
AB  - Children with autism spectrum disorder (ASD) are at greater risk for experiencing high levels of anxiety symptoms. 

Recent evidence suggests Cognitive behavioral therapy (CBT) may also be effective for anxiety reduction in some presentations of ASD. 

This meta-analysis evaluated twenty-three studies.
AN  - 30810842
AU  - Perihan,
AU  - C.
AU  - Burke,
AU  - M.
AU  - Bowman-Perrott,
AU  - L.
AU  - Bicer,
AU  - A.
AU  - Gallup,
AU  - J.
AU  - Thompson,
AU  - J.
AU  - Sallese,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10803-019-03949-7
L1  - internal-pdf://0409979193/Perihan-2019-Effects of Cognitive Behavioral T.pdf
PY  - 2019
SP  - 27
T2  - Journal of Autism &amp; Developmental Disorders
TI  - Effects of Cognitive Behavioral Therapy for Reducing Anxiety in Children with High Functioning ASD: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30810842
UR  - https://link.springer.com/article/10.1007%2Fs10803-019-03949-7
VL  - 27
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** 
The current study was performed to assess the evidence for effects of therapeutic intervention with mobile device applications (apps) for individuals with autism spectrum disorder (ASD).

**DESIGN:** 
The main methodology of the current study was systematic review with meta-analysis.SETTING: Only randomised controlled trials (RCTs) for mobile device apps for individuals with ASD were considered for review in the current study.

**PATIENTS:** 
The target population was individuals clinically diagnosed with ASD.

**INTERVENTIONS:**
Applications that are operable on a smart (mobile) device and interactive with users.

**MAIN OUTCOME MEASURES:** 
The main outcomes were based on standardised mean differences in pretrial and post-trial scales in each control and intervention group.

**RESULTS:**
Out of a total of 1100 studies (after duplicate removal), 7 RCTs were selected for final analysis. Of the seven studies, two RCTs were further analysed for effects based on the visual and fine motor subscales of the Mullen Scales of Early Learning, which favoured the intervention groups (standardised mean difference (SMD)=0.41, 95% CI 0.03 to 0.80; SMD=0.41, 95% CI 0.03 to 0.80), without either having any heterogeneity (p&gt;0.1) or publication bias.

**CONCLUSIONS:** 
Although it is still early to draw a conclusion, available studies are showing promise for use of mobile device apps for treatment of individuals with ASD. More well-designed and large-scale studies focused on improving behavioural symptoms of ASD are warranted.Prospero registration number: Crd42019128362.
AD  - Moon, Sun Jae. Ewha Women&#039;s University Mokdong Hospital, Seoul, Republic of Korea sunjaemoon16@gmail.com.Hwang, Jinseub. Statistics, Daegu University, Gyeongsan, Republic of Korea.Hill, Harrison Scott. Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.Kervin, Ryan. School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.Birtwell, Kirstin Brown. Lurie Center for Autism; Massachusetts General Hospital; Harvard Medical School, Boston, Massachusetts, USA.Torous, John. Psychiatry, Beth Israel Deaconess Medical Center; Harvard Medical School, Boston, Massachusetts, USA.McDougle, Christopher J. Lurie Center for Autism; Massachusetts General Hospital; Harvard Medical School, Boston, Massachusetts, USA.Kim, Jung Won. Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
AN  - 31848147
AU  - Moon,
AU  - S.
AU  - J.
AU  - Hwang,
AU  - J.
AU  - Hill,
AU  - H.
AU  - S.
AU  - Kervin,
AU  - R.
AU  - Birtwell,
AU  - K.
AU  - B.
AU  - Torous,
AU  - J.
AU  - McDougle,
AU  - C.
AU  - J.
AU  - Kim,
AU  - J.
AU  - W.
DA  - Dec 17
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1136/archdischild-2019-318258
DP  - Ovid Technologies
J2  - Arch Dis Child
L1  - internal-pdf://0929738439/Moon-2019-Mobile device applications and treat.pdf
LA  - English
N1  - Using Smart Source ParsingDecMoon, Sun JaeHwang, JinseubHill, Harrison ScottKervin, RyanBirtwell, Kirstin BrownTorous, JohnMcDougle, Christopher JKim, Jung Wonarchdischild-2019-318258
PY  - 2019
SP  - 17
T2  - Archives of Disease in Childhood
TI  - Mobile device applications and treatment of autism spectrum disorder: a systematic review and meta-analysis of effectiveness
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31848147
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31848147&amp;id=doi:10.1136%2Farchdischild-2019-318258&amp;issn=0003-9888&amp;isbn=&amp;volume=&amp;issue=&amp;spage=archdischi&amp;pages=&amp;date=2019&amp;title=Archives+of+Disease+in+Childhood&amp;atitle=Mobile+device+applications+and+treatment+of+autism+spectrum+disorder%3A+a+systematic+review+and+meta-analysis+of+effectiveness.&amp;aulast=Moon&amp;pid=%3Cauthor%3EMoon+SJ%3C%2Fauthor%3E%3CAN%3E31848147%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://adc.bmj.com/content/archdischild/early/2019/12/17/archdischild-2019-318258.full.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - OBJECTIVE: 
To synthesise randomised controlled trials (RCTs) regarding the effects of chronic exercise interventions on different domain-specific executive functions (EFs) among children and adolescents.

DESIGN: 
Systematic review with meta-analysis.DATA SOURCES: PsycINFO, PubMed, SPORTDiscus, Academic Search Premier, Embase and Web of Science were searched.

ELIGIBILITY CRITERIA FOR SELECTING STUDIES: 
RCTs or cluster RCT design, which employ chronic exercise interventions and target healthy children (age 6-12 years) and adolescents (age 13-17 years). We defined chronic exercise as physical activity (PA) which consists of multiple exercise sessions per week and lasts for an extended period of time (typically over 6 weeks).

RESULTS: 
We included 19 studies, with a total of 5038 participants. The results showed that chronic exercise interventions improved overall EFs (standardised mean difference (SMD)=0.20, 95% CI 0.09 to 0.30, p&lt;0.05) and inhibitory control (SMD=0.26, 95% CI 0.08 to 0.45, P&lt;0.05). In meta regression, higher body mass index was associated with greater improvements in overall EFs performance (beta=0.03, 95% CI 0.0002 to 0.06, p&lt;0.05), whereas age and exercise duration were not. In subgroup analysis by intervention modality, sports and PA programme (SMD=0.21, 95% CI 0.12 to 0.31, p&lt;0.05) and curricular PA (SMD=0.39, 95% CI 0.08 to 0.69, p&lt;0.05) improved overall EFs performance, but integrated PA did not (SMD=0.02, 95% CI -0.05 to 0.09, p&gt;0.05). Interventions with a session length &lt; 90 minutes improved overall EFs performance (SMD=0.24, 95%CI 0.10 to 0.39, p=0.02), but session length &gt;= 90 minutes did not (SMD=0.05, 95%CI -0.03 to 0.14). No other moderator was found to have an effect.

CONCLUSIONS: 
Despite small effect sizes, chronic exercise interventions, implemented in curricular or sports and PA programme settings, might be a promising way to promote multiple aspects of executive functions, especially inhibitory control.
AD  - Xue, Yue. Department of Physical Education, Shanghai Jiao Tong University, Shanghai, China.Xue, Yue. School of Kinesiology, University of Minnesota, Minneapolis, Minnesota, USA.Yang, Yanxiang. Department of Physical Education, Shanghai Jiao Tong University, Shanghai, China.Huang, Tao. Department of Physical Education, Shanghai Jiao Tong University, Shanghai, China.
AN  - 30737201
AU  - Xue,
AU  - Y.
AU  - Yang,
AU  - Y.
AU  - Huang,
AU  - T.
DA  - Nov
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1136/bjsports-2018-099825
DP  - Ovid Technologies
J2  - BJSM online
KW  - Adolescent
KW  - Body Mass Index
KW  - Child
KW  - *Executive Function
KW  - *Exercise
KW  - Humans
KW  - Inhibition (Psychology)
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://1474802180/Xue-2019-Effects of chronic exercise intervent.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Xue, YueYang, YanxiangHuang, Tao
PY  - 2019
SP  - 1397-1404
T2  - British Journal of Sports Medicine
TI  - Effects of chronic exercise interventions on executive function among children and adolescents: a systematic review with meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=30737201
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30737201&amp;id=doi:10.1136%2Fbjsports-2018-099825&amp;issn=0306-3674&amp;isbn=&amp;volume=53&amp;issue=22&amp;spage=1397&amp;pages=1397-1404&amp;date=2019&amp;title=British+Journal+of+Sports+Medicine&amp;atitle=Effects+of+chronic+exercise+interventions+on+executive+function+among+children+and+adolescents%3A+a+systematic+review+with+meta-analysis.&amp;aulast=Xue&amp;pid=%3Cauthor%3EXue+Y%3C%2Fauthor%3E%3CAN%3E30737201%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://bjsm.bmj.com/content/bjsports/53/22/1397.full.pdf
VL  - 53
ER  -
TY  - JOUR
AB  - **Objective** 
To systematically evaluate the efficacy of treatments for tics and the risks associated with their use. 

**Methods** 
This project followed the methodologies outlined in the 2011 edition of the American Academy of Neurology&#039;s guideline development process manual. We included systematic reviews and randomized controlled trials on the treatment of tics that included at least 20 participants (10 participants if a crossover trial), except for neurostimulation trials, for which no minimum sample size was required. To obtain additional information on drug safety, we included cohort studies or case series that specifically evaluated adverse drug effects in individuals with tics. 

**Results** 
There was high confidence that the Comprehensive Behavioral Intervention for Tics was more likely than psychoeducation and supportive therapy to reduce tics. There was moderate confidence that haloperidol, risperidone, aripiprazole, tiapride, clonidine, onabotulinumtoxinA injections, 5-ling granule, Ningdong granule, and deep brain stimulation of the globus pallidus were probably more likely than placebo to reduce tics. There was low confidence that pimozide, ziprasidone, metoclopramide, guanfacine, topiramate, and tetrahydrocannabinol were possibly more likely than placebo to reduce tics. Evidence of harm associated with various treatments was also demonstrated, including weight gain, drug-induced movement disorders, elevated prolactin levels, sedation, and effects on heart rate, blood pressure, and ECGs. 

**Conclusions** 
There is evidence to support the efficacy of various medical, behavioral, and neurostimulation interventions for the treatment of tics. Both the efficacy and harms associated with interventions must be considered in making treatment recommendations.
AD  - [Pringsheim, Tamara; Martino, Davide] Univ Calgary, Cumming Sch Med, Dept Clin Neurosci Psychiat Pediat &amp; Community Hl, Calgary, AB, Canada. [Holler-Managan, Yolanda] Northwestern Univ, Feinberg Sch Med, Dept Pediat Neurol, Chicago, IL 60611 USA. [Okun, Michael S.] Univ Florida, Fixel Ctr Neurol Dis, Dept Neurol, Gainesville, FL USA. [Okun, Michael S.] Univ Florida, Fixel Ctr Neurol Dis, Dept Neurosurg, Gainesville, FL USA. [Jankovic, Joseph] Baylor Coll Med, Dept Neurol, Houston, TX 77030 USA. [Piacentini, John] Univ Calif Los Angeles, Semel Inst Neurosci &amp; Human Behav, Dept Psychiat &amp; Biobehav Sci, Los Angeles, CA 90024 USA. [Cavanna, Andrea E.] Univ Birmingham, BSMHFT, Dept Neuropsychiat, Birmingham, W Midlands, England. Aston Univ, Birmingham, W Midlands, England. [Mueller-Vahl, Kirsten] Hannover Med Sch, Dept Psychiat Social Psychiat &amp; Psychotherapy, Hannover, Germany. [Woods, Douglas W.] Marquette Univ, Dept Psychol, Milwaukee, WI 53233 USA. [Robinson, Michael] Tourette Assoc Amer, Massachusetts Chapter, Bayside, NY USA. [Jarvie, Elizabeth] Univ Wisconsin, Waisman Ctr, Univ Ctr Excellence Dev Disabil, Madison, WI 53705 USA. [Roessner, Veit] Tech Univ Dresden, Dresden, Germany. [Oskoui, Maryam] McGill Univ, Dept Pediat, Montreal, PQ, Canada. [Oskoui, Maryam] McGill Univ, Dept Neurol Neurosurg, Montreal, PQ, Canada.Pringsheim, T (reprint author), Univ Calgary, Cumming Sch Med, Dept Clin Neurosci Psychiat Pediat &amp; Community Hl, Calgary, AB, Canada.guidelines@aan.com
AN  - WOS:000480764300022
AU  - Pringsheim,
AU  - T.
AU  - Holler-Managan,
AU  - Y.
AU  - Okun,
AU  - M.
AU  - S.
AU  - Jankovic,
AU  - J.
AU  - Piacentini,
AU  - J.
AU  - Cavanna,
AU  - A.
AU  - E.
AU  - Martino,
AU  - D.
AU  - Muller-Vahl,
AU  - K.
AU  - Woods,
AU  - D.
AU  - W.
AU  - Robinson,
AU  - M.
AU  - Jarvie,
AU  - E.
AU  - Roessner,
AU  - V.
AU  - Oskoui,
AU  - M.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1212/wnl.0000000000007467
J2  - Neurology
KW  - placebo-controlled trial
KW  - deficit hyperactivity disorder
KW  - medicine
KW  - ningdong granule
KW  - quality-of-life
KW  - double-blind
KW  - delta(9)-tetrahydrocannabinol thc
KW  - behavior-therapy
KW  - children
KW  - adolescents
KW  - haloperidol
KW  - Neurosciences &amp; Neurology
L1  - internal-pdf://1319454366/Pringsheim-2019-Comprehensive systematic revie.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: IQ5AUTimes Cited: 0Cited Reference Count: 60Pringsheim, Tamara Holler-Managan, Yolanda Okun, Michael S. Jankovic, Joseph Piacentini, John Cavanna, Andrea E. Martino, Davide Mueller-Vahl, Kirsten Woods, Douglas W. Robinson, Michael Jarvie, Elizabeth Roessner, Veit Oskoui, MaryamAmerican Academy of Neurology (AAN)This practice guideline was developed with financial support from the American Academy of Neurology (AAN). Authors who serve as AAN subcommittee members (Y.H.-M., M.O.) or as methodologists (T.P.), or who are AAN staff (S.M.), were reimbursed by the AAN for expenses related to travel to subcommittee meetings where drafts of manuscripts were reviewed.01Lippincott williams &amp; wilkinsPhiladelphia1526-632x
PY  - 2019
SP  - 907-915
T2  - Neurology
TI  - Comprehensive systematic review summary: Treatment of tics in people with Tourette syndrome and chronic tic disorders
UR  - &lt;Go to ISI&gt;://WOS:000480764300022
UR  - https://n.neurology.org/content/neurology/92/19/907.full.pdf
VL  - 92
ER  -
TY  - JOUR
AB  - Foster and adoptive parents often face challenges while taking care of children who, due to their adverse early life experiences, are at risk of developing insecure attachment relationships, behavior problems, and stress dysregulation. Several intervention programs have been developed to help foster and adoptive parents to overcome these challenges. In the current study, a series of eight meta-analyses were performed to examine the effectiveness of these intervention programs on four parent outcomes (sensitive parenting, k = 11, N = 684; dysfunctional discipline, k = 4, N = 239; parenting knowledge and attitudes, k = 7, N = 535; parenting stress, k = 18, N = 1,306), three child outcomes (attachment security, k = 6, N = 395; behavior problems, k = 33, N = 2,661; diurnal cortisol levels, k = 3, N = 261), and placement disruption (k = 7, N = 1,100).
AD  - Schoemaker, Nikita K. Institute of Education and Child Studies, Leiden University,Leiden,The Netherlands.Wentholt, Wilma G M. Institute of Education and Child Studies, Leiden University,Leiden,The Netherlands.Goemans, Anouk. Institute of Education and Child Studies, Leiden University,Leiden,The Netherlands.Vermeer, Harriet J. Institute of Education and Child Studies, Leiden University,Leiden,The Netherlands.Juffer, Femmie. Institute of Education and Child Studies, Leiden University,Leiden,The Netherlands.Alink, Lenneke R A. Institute of Education and Child Studies, Leiden University,Leiden,The Netherlands.
AN  - 31366418
AU  - Schoemaker,
AU  - N.
AU  - K.
AU  - Wentholt,
AU  - W.
AU  - G.
AU  - M.
AU  - Goemans,
AU  - A.
AU  - Vermeer,
AU  - H.
AU  - J.
AU  - Juffer,
AU  - F.
AU  - Alink,
AU  - L.
AU  - R.
AU  - A.
DA  - Aug 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1017/S0954579419000798
DP  - Ovid Technologies
J2  - Dev Psychopathol
L1  - internal-pdf://2824816724/Schoemaker-2019-A meta-analytic review of pare.pdf
LA  - English
N1  - Schoemaker, Nikita KWentholt, Wilma G MGoemans, AnoukVermeer, Harriet JJuffer, FemmieAlink, Lenneke R A
PY  - 2019
SP  - 1-24
T2  - Development &amp; Psychopathology
TI  - A meta-analytic review of parenting interventions in foster care and adoption
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31366418
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31366418&amp;id=doi:10.1017%2FS0954579419000798&amp;issn=0954-5794&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-24&amp;date=2019&amp;title=Development+%26+Psychopathology&amp;atitle=A+meta-analytic+review+of+parenting+interventions+in+foster+care+and+adoption.&amp;aulast=Schoemaker&amp;pid=%3Cauthor%3ESchoemaker+NK%3C%2Fauthor%3E%3CAN%3E31366418%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/3FC41F78B9B1B4582CBD9E37BA1DB6EF/S0954579419000798a.pdf/div-class-title-a-meta-analytic-review-of-parenting-interventions-in-foster-care-and-adoption-div.pdf
ER  -
TY  - JOUR
AB  - **Background**
Parents and carers have a major influence on children&#039;s learning and development from birth, through the school years, and into adulthood. Parental contributions to education include providing a secure environment in which to learn, providing intellectual stimulation, transmitting social norms and values, shaping the child&rsquo;s resilience through fostering literacy and problem‐solving, and encouraging personal and social aspiration. Increasingly, providers of formalised education are recognising the primary role of parents, carers, and the wider family, as well as peers and the environment, in shaping children&#039;s education, health, and life experiences.

**Objectives**
To assess the effectiveness of the Families and Schools Together (FAST) programme in improving outcomes among children and their families.

**Search methods**
Between October 2018 and December 2018, we searched CENTRAL, MEDLINE, Embase, PsycINFO, 11 additional databases, and three trial registers. We handsearched the reference lists of included studies and relevant reports and reviews, contacted the programme developer and independent researchers, and searched relevant websites to identify other eligible studies.

**Selection criteria**
We included randomised controlled trials (RCTs) and quasi‐RCTs examining the effects of FAST, relative to waiting list, usual or alternative services, or no intervention, on outcomes for children (aged from birth to completion of compulsory education) and their families.

**Data collection and analysis**
At least two review authors independently evaluated the records retrieved from the search for relevance. One review author (JV) extracted data from eligible studies with a second independent review author (AF, DK, or SL). Review authors consulted with one another to resolve disagreements. We used a fixed‐effect model for meta‐analysis. We presented results as standardised mean differences (SMDs) because all outcomes were continuously scaled, and we accompanied these with 95% confidence intervals (CIs). We used the GRADE approach to assess the certainty of evidence for each outcome.

**Main results**
We identified 10 completed RCTs, most of which were relatively recent (2007 or later) and were conducted with at least some involvement from the intervention developer or the FAST organisation. Nine of the 10 trials were from the USA; the other was from the UK. Children were young (five to nine years old; mean age approximately six years), and therefore, whilst not so named in the reports, evaluations consisted of what is sometimes referred to as &#039;Kids FAST&#039; and sometimes &#039;Elementary Level FAST&#039;). Among the USA‐based studies, at least 62% of participants were members of a racial/ethnic minority group (most commonly, African American or Latino). FAST was usually delivered in schools after the school day. Trials lasted about eight weeks and usually examined the effects of FAST relative to no additional intervention. Most studies were funded by agencies in the US federal government. We judged the certainty of evidence in the included studies to be moderate or low for the main review outcomes. Failure to include all families in outcome analyses (attrition) and possible bias in recruitment of families into the trials were the main limitations in the evidence.We included over 9000 children and their families in at least one meta‐analysis. The follow results relate to meta‐analyses of data at long‐term follow‐up.

Primary outcomes:
Four studies (approximately 6276 children) assessed child school performance at long‐term follow‐up. The effect size was very small, and the CI did not include effects that, if real, suggest possibly important positive or negative effects if viewed from an individual perspective (SMD ‐0.02, 95% CI ‐0.11 to 0.08). We assessed the certainty of evidence for this outcome as moderate. No studies assessed child adverse events, parental substance use, or parental stress.

Secondary outcomes:
Parent reports of child internalising behaviour (SMD ‐0.03, 95% CI ‐0.11 to 0.17; 4 RCTs, approximately 908 children; low‐certainty evidence) and family relationships (SMD 0.08, 95% CI ‐0.03 to 0.19; 4 RCTs, approximately 2569 children; moderate‐certainty evidence) also yielded CIs that did not include effects that, if real, suggest possibly important positive or negative effects.The CI for parent reports of child externalising behaviour, however, did include effects that, if real, were possibly large enough to be important (SMD ‐0.19, 95% CI ‐0.32 to ‐0.05; 4 RCTs, approximately 754 children; low‐certainty evidence).

**Authors&#039; conclusions**
Given these results, it is hard to support the assertion that assignment to FAST is associated with important positive outcomes for children and their parents.
AU  - Valentine,
AU  - J.
AU  - C.
AU  - Leach,
AU  - S.
AU  - M.
AU  - Fowler,
AU  - A.
AU  - P.
AU  - Stojda,
AU  - D.
AU  - K.
AU  - Macdonald,
AU  - G.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD012760.pub2
L1  - internal-pdf://1807665360/Valentine-2019-Families and Schools Together (.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Families and Schools Together (FAST) for improving outcomes for children and their families
ER  -
TY  - JOUR
AB  - **Background**
When sufficient maternal breast milk is not available, alternative forms of enteral nutrition for preterm or low birth weight (LBW) infants are donor breast milk or artificial formula. Donor breast milk may retain some of the non‐nutritive benefits of maternal breast milk for preterm or LBW infants. However, feeding with artificial formula may ensure more consistent delivery of greater amounts of nutrients. Uncertainty exists about the balance of risks and benefits of feeding formula versus donor breast milk for preterm or LBW infants.

**Objectives**
To determine the effect of feeding with formula compared with donor breast milk on growth and development in preterm or low birth weight (LBW) infants.Search methodsWe used the Cochrane Neonatal search strategy, including electronic searches of the Cochrane Central Register of Controlled Trials (CENTRAL; 2019, Issue 5), Ovid MEDLINE, Embase, and the Cumulative Index to Nursing and Allied Health Literature (3 May 2019), as well as conference proceedings, previous reviews, and clinical trials.

**Selection criteria**
Randomised or quasi‐randomised controlled trials (RCTs) comparing feeding with formula versus donor breast milk in preterm or LBW infants.

**Data collection and analysis**
Two review authors assessed trial eligibility and risk of bias and extracted data independently. We analysed treatment effects as described in the individual trials and reported risk ratios (RRs) and risk differences (RDs) for dichotomous data, and mean differences (MDs) for continuous data, with respective 95% confidence intervals (CIs). We used a fixed‐effect model in meta‐analyses and explored potential causes of heterogeneity in subgroup analyses. We assessed the certainty of evidence for the main comparison at the outcome level using GRADE methods.

**Main results**
Twelve trials with a total of 1879 infants fulfilled the inclusion criteria. Four trials compared standard term formula versus donor breast milk and eight compared nutrient‐enriched preterm formula versus donor breast milk. Only the five most recent trials used nutrient‐fortified donor breast milk. The trials contain various weaknesses in methodological quality, specifically concerns about allocation concealment in four trials and lack of blinding in most of the trials. Most of the included trials were funded by companies that made the study formula.Formula‐fed infants had higher in‐hospital rates of weight gain (mean difference (MD) 2.51, 95% confidence interval (CI) 1.93 to 3.08 g/kg/day), linear growth (MD 1.21, 95% CI 0.77 to 1.65 mm/week) and head growth (MD 0.85, 95% CI 0.47 to 1.23 mm/week). These meta‐analyses contained high levels of heterogeneity. We did not find evidence of an effect on long‐term growth or neurodevelopment. Formula feeding increased the risk of necrotising enterocolitis (typical risk ratio (RR) 1.87, 95% CI 1.23 to 2.85; risk difference (RD) 0.03, 95% CI 0.01 to 0.05; number needed to treat for an additional harmful outcome (NNTH) 33, 95% CI 20 to 100; 9 studies, 1675 infants).The GRADE certainty of evidence was moderate for rates of weight gain, linear growth, and head growth (downgraded for high levels of heterogeneity) and was moderate for neurodevelopmental disability, all‐cause mortality, and necrotising enterocolitis (downgraded for imprecision).

**Authors&#039; conclusions**
In preterm and LBW infants, moderate‐certainty evidence indicates that feeding with formula compared with donor breast milk, either as a supplement to maternal expressed breast milk or as a sole diet, results in higher rates of weight gain, linear growth, and head growth and a higher risk of developing necrotising enterocolitis. The trial data do not show an effect on all‐cause mortality, or on long‐term growth or neurodevelopment.
AU  - Quigley,
AU  - M.
AU  - Embleton,
AU  - N.
AU  - D.
AU  - McGuire,
AU  - W.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD002971.pub5
L1  - internal-pdf://3902327195/Quigley-2019-Formula versus donor breast milk.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Formula versus donor breast milk for feeding preterm or low birth weight infants
ER  -
TY  - JOUR
AB  - **Background:** 
A major challenge in providing mental health interventions for young people is making such interventions accessible and appealing to those most in need. Online and app-based forms of therapy for mental health are burgeoning. It is therefore crucial to identify features that are most effective and engaging for young users. 

**Objective(s):** 
This study reports a systematic review and meta-analysis of digital mental health interventions and their effectiveness in addressing anxiety and depression in young people to determine factors that relate to outcomes, adherence, and engagement with such interventions. 

**Method(s):** 
A mixed methods approach was taken, including a meta-analysis of 9 randomized controlled trials that compared use of a digital intervention for depression in young people to a no-intervention control group, and 6 comparing the intervention to an active control condition. A thematic analysis and narrative synthesis of 41 studies was also performed. 

**Result(s):** 
The pooled effect size of digital mental health interventions on depression in comparison to a no-intervention control was small (Cohen&#039;s d = 0.33, 95% CI 0.11 to 0.55), while the pooled effect size of studies comparing an intervention group to an active control showed no significant differences (Cohen&#039;s d = 0.14, 95% CI -.04 to 0.31). Pooled effect sizes were higher when supervision was involved (studies with no-intervention controls: Cohen&#039;s d = 0.52, 95% CI 0.23 to 0.80; studies with active control: Cohen&#039;s d = 0.49, 95% CI -0.11, 1.01). Engagement and adherence rates were low. Qualitative analysis revealed that users liked interventions with a game-like feel and relatable, interactive content. Educational materials were perceived as boring, and users were put off by non-appealing interfaces and technical glitches. 

**Conclusion(s):** 
Digital interventions work better than no intervention to improve depression in young people when results of different studies are pooled together. However, these interventions may only be of clinical significance when use is highly supervised. Digital interventions do not work better than active alternatives regardless of the level of support. Future interventions need to move beyond the use of digital educational materials, considering other ways to attract and engage young people and to ensure relevance and appeal. &copy; Copyright &copy; 2019 Garrido, Millington, Cheers, Boydell, Schubert, Meade and Nguyen.
AD  - (Garrido, Millington, Cheers) MARCS Institute for Brain, Behaviour &amp; Development, Western Sydney University, Milperra, NSW, Australia (Garrido) Translational Health Institute, Western Sydney University, Campbelltown, NSW, Australia (Garrido, Meade) School of Social Sciences &amp; Psychology, Western Sydney University, Milperra, NSW, Australia (Cheers) NSW Health, Sydney, NSW, Australia (Boydell) Blackdog Institute, Randwick, NSW, Australia (Schubert) School of Arts &amp; Humanities, University of New South Wales, Kensington, NSW, Australia (Nguyen) School of Computing &amp; Engineering, Western Sydney University, Parramatta, NSW, AustraliaS. Garrido, MARCS Institute for Brain, Behaviour &amp; Development, Western Sydney University, Milperra, NSW, Australia. E-mail: s.garrido@westernsydney.edu.au
AN  - 629992010
AU  - Garrido,
AU  - S.
AU  - Millington,
AU  - C.
AU  - Cheers,
AU  - D.
AU  - Boydell,
AU  - K.
AU  - Schubert,
AU  - E.
AU  - Meade,
AU  - T.
AU  - Nguyen,
AU  - Q.
AU  - V.
DA  - 13 Nov
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3389/fpsyt.2019.00759
DP  - Ovid Technologies
KW  - adolescents
KW  - children
KW  - low mood
KW  - prevention
KW  - self-management
KW  - unguided self-help
KW  - acceptance and commitment therapy
KW  - anxiety disorder/th [Therapy]
KW  - cognitive behavioral therapy
KW  - depression/th [Therapy]
KW  - effect size
KW  - health education
KW  - human
KW  - Internet
KW  - juvenile
KW  - mental health service
KW  - meta analysis
KW  - mobile application
KW  - motivational interviewing
KW  - outcome assessment
KW  - patient attitude
KW  - patient compliance
KW  - peer group
KW  - qualitative analysis
KW  - randomized controlled trial (topic)
KW  - review
KW  - systematic review
KW  - telemedicine
KW  - text messaging
KW  - video game
KW  - computer interface
KW  - healthcare software
KW  - digital mental health intervention
L1  - internal-pdf://3914641002/Garrido-2019-What Works and What Doesn&#039;t Work_.pdf
LA  - English
M3  - Review
PY  - 2019
T2  - Frontiers in Psychiatry
TI  - What Works and What Doesn&#039;t Work? A Systematic Review of Digital Mental Health Interventions for Depression and Anxiety in Young People
UR  - http://www.frontiersin.org/Psychiatry
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=629992010
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/441740/pubmed-zip/.versions/2/.package-entries/fpsyt-10-00759.pdf?sv=2015-12-11&amp;sr=b&amp;sig=I1zD0aDaJdfiaLaQZvv%2FA%2FtPhxCj%2Fs9T6LqH%2BJLKWdQ%3D&amp;se=2020-01-07T12%3A04%3A23Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyt-10-00759.pdf
VL  - 10 (no pagination)
ER  -
TY  - JOUR
AB  - **Background**
When human milk is not available for feeding preterm infants, protein hydrolysate, rather than standard cow&#039;s milk formulas (with intact proteins), is often used because it is perceived as being tolerated better and less likely to lead to complications. However, protein hydrolysate formulas are more expensive than standard formulas, and concern exists that their use in practice is not supported by high‐quality evidence.

**Objectives**
To assess the effects of feeding preterm infants hydrolysed formula (vs standard cow&#039;s milk formula) on risk of feed intolerance, necrotising enterocolitis, and other morbidity and mortality.

**Search methods**
We used the standard Cochrane Neonatal search strategy including electronic searches of the Cochrane Central Register of Controlled Trials (CENTRAL; 2019, Issue 1), in the Cochrane Library; Ovid MEDLINE (1966 to 28 January 2019); Ovid Embase (1980 to 28 January 2019); and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) (28 January 2019), as well as conference proceedings and previous reviews.Selection criteriaRandomised and quasi‐randomised controlled trials that compared feeding preterm infants protein hydrolysate versus standard (non‐hydrolysed) cow&#039;s milk formula.

**Data collection and analysis**
Two review authors assessed trial eligibility and risk of bias and extracted data independently. We analysed treatment effects as described in the individual trials and reported risk ratios and risk differences for dichotomous data, and mean differences for continuous data, with respective 95% confidence intervals (CIs). We used a fixed‐effect model in meta‐analyses and explored potential causes of heterogeneity in sensitivity analyses. We assessed quality of evidence at the outcome level using the GRADE approach.

**Main results**
We identified 11 trials for inclusion in the review. All trials were small (total participants 665) and had various methodological limitations including uncertainty about methods to ensure allocation concealment and blinding. Most participants were clinically stable preterm infants of less than about 34 weeks&#039; gestational age or with birth weight less than about 1750 g. Fewer participants were extremely preterm, extremely low birth weight, or growth restricted. Most trials found no effects on feed intolerance, assessed variously as mean pre‐feed gastric residual volume, incidence of abdominal distension or other gastrointestinal signs of concern, or time taken to achieve full enteral feeds (meta‐analysis was limited because studies used different measures). Meta‐analysis showed no effect on the risk of necrotising enterocolitis (typical risk ratio 1.10, 95% CI 0.36 to 3.34; risk difference 0.00, 95% CI ‐0.03 to 0.04; 5 trials, 385 infants) (low‐certainty evidence; downgraded for imprecision and design weaknesses).

**Authors&#039; conclusions**
The identified trials provide only low‐certainty evidence about the effects of feeding preterm infants protein hydrolysate versus standard formula. Existing data do not support conclusions that feeding protein hydrolysate affects the risk of feed intolerance or necrotising enterocolitis. Additional large, pragmatic trials are needed to provide more reliable and precise estimates of effectiveness and cost‐effectiveness.
AU  - Ng,
AU  - D.
AU  - H.
AU  - C.
AU  - Klassen,
AU  - J.
AU  - R.
AU  - Embleton,
AU  - N.
AU  - D.
AU  - McGuire,
AU  - W.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD012412.pub3
L1  - internal-pdf://2192295019/Ng-2019-Protein hydrolysate versus standard fo.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Protein hydrolysate versus standard formula for preterm infants
ER  -
TY  - JOUR
AB  - **Background**
Preventing suicide and self-harm is a global health priority. Although there is a growing evidence base for the effectiveness of psychoanalytic and psychodynamic psychotherapies for a range of disorders, to date there has been no systematic review of its effectiveness in reducing suicidal and self-harming behaviours. 

**Aims** 
To systematically review randomised controlled trials of psychoanalytic and psychodynamic psychotherapies for suicidal attempts and self-harm. 

**Method** 
We searched PubMed, PsycINFO, Psycharticles, CINAHL, EMBASE and the Cochrane Central Register of Controlled Trials for randomise controlled trials of psychoanalytic and psychodynamic psychotherapies for reducing suicide attempts and self-harm. 

**Results** 
Twelve trials (17 articles) were included in the meta-analyses. Psychoanalytic and psychodynamic therapies were effective in reducing the number of patients attempting suicide (pooled odds ratio, 0.469; 95% CI 0.274-0.804). We found some evidence for significantly reduced repetition of self-harm at 6-month but not 12-month follow-up. Significant treatment effects were also found for improvements in psychosocial functioning and reduction in number of hospital admissions. 

**Conclusions** 
Psychoanalytic and psychodynamic psychotherapies are indicated to be effective in reducing suicidal behaviour and to have short-term effectiveness in reducing self-harm. They can also be beneficial in improving psychosocial well-being. However, the small number of trials and moderate quality of the evidence means further high-quality trials are needed to confirm our findings and to identity which specific components of the psychotherapies are effective.
AN  - WOS:000471749700003
AU  - Briggs,
AU  - S.
AU  - Netuveli,
AU  - G.
AU  - Gould,
AU  - N.
AU  - Gkaravella,
AU  - A.
AU  - Gluckman,
AU  - N.
AU  - S.
AU  - Kangogyere,
AU  - P.
AU  - Farr,
AU  - R.
AU  - Goldblatt,
AU  - M.
AU  - J.
AU  - Lindner,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://doi.org/10.1192/bjp.2019.33
L1  - internal-pdf://4264205084/Briggs-2019-The effectiveness of psychoanalyti.pdf
PY  - 2019
SP  - 320-328
T2  - British Journal of Psychiatry
TI  - The effectiveness of psychoanalytic/ psychodynamic psychotherapy for reducing suicide attempts and self-harm: systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000471749700003
UR  - https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/effectiveness-of-psychoanalyticpsychodynamic-psychotherapy-for-reducing-suicide-attempts-and-selfharm-systematic-review-and-metaanalysis/389C98850F875893D54996597DF6DF3A
VL  - 214
ER  -
TY  - JOUR
AB  - **Background:** 
Obsessive-compulsive disorder (OCD) is a common behavioral disorder among adolescents and children. The selective serotonin reuptake inhibitors (SSRIs) are the first pharmacological choice for this condition due to mild adverse effect profile. 

**Objective:** 
This systematic review was performed to evaluate the efficacy of SSRI for OCD in adolescents and children. 

**Methods:** 
Search terms were entered into PubMed, PsycINFO, Scopus, CINAHL, and Google Scholar. The included studies were randomized, placebo-controlled trials of SSRIs conducted in populations of children and adolescents younger than 18 years. Change from baseline Children&#039;s Yale-Brown Obsessive-Compulsive Scale (CY-BOCS), end-treatment CY-BOCS with respective SD, and response and remission rates were collected for continuous and dichotomous outcome assessment, respectively. Cochrane Rev Man software was used for meta-analyses, providing Forest plots where applicable. 

**Results:** 
SSRIs were superior to placebo with a small effect size. There was no additional benefit of combination treatment over cognitive behavioral therapy (CBT) alone, but CBT added substantial benefit to SSRI monotherapy. Fluoxetine and sertraline appear to be superior to fluvoxamine. 

**Conclusion:** 
The results of current systematic review and meta-analysis support the existing National Institute for Health and Care Excellence (NICE) guidelines for choosing CBT as first line of treatment and substituting it with SSRI, depending on patient preference. Adding CBT to current SSRI treatment is effective for non-responders and partial responders, but adding SSRI to ongoing CBT does not prove beneficial. The SSRIs have different effectiveness, and their relative efficacy remains to be investigated.
AD  - [Kotapati, Vijaya Padma] Manhattan Psychiat Ctr, Dept Mental Hlth, New York, NY 10035 USA. [Khan, Ali M.] Univ Texas Rio Grande Valley Edinburg, Dept Mental Hlth, Edinburg, TX USA. [Dar, Sara] Harvard Med Sch, Brigham &amp; Womens Hosp, Dept Mental Hlth, Boston, MA 02115 USA. [Begum, Guishan] Jamaica Hosp Med Ctr, Dept Mental Hlth, Richmond Hill, NY USA. [Bachu, Ramya] Zucker Hillside Hosp, Dept Mental Hlth, Glen Oaks, NY USA. [Adnan, Mahwish] Mc Master Univ, Dept Mental Hlth, Hamilton, ON, Canada. [Zubair, Aarij] St Johns Univ, Dept Mental Hlth, Queens, NY USA. [Ahmed, Rizwan A.] Liaquat Univ Med &amp; Hlth Sci, Dept Mental Hlth, Sindh, Pakistan.Kotapati, VP (reprint author), Manhattan Psychiat Ctr, Dept Mental Hlth, New York, NY 10035 USA.padmakotapati89@gmail.com
AN  - WOS:000478898100001
AU  - Kotapati,
AU  - V.
AU  - P.
AU  - Khan,
AU  - A.
AU  - M.
AU  - Dar,
AU  - S.
AU  - Begum,
AU  - G.
AU  - Bachu,
AU  - R.
AU  - Adnan,
AU  - M.
AU  - Zubair,
AU  - A.
AU  - Ahmed,
AU  - R.
AU  - A.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3389/fpsyt.2019.00523
J2  - Front. Psychiatry
KW  - selective serotonin reuptake inhibitors
KW  - obsessive-compulsive disorder
KW  - adolescents
KW  - children
KW  - cognitive behavioral therapy
KW  - cognitive-behavioral therapy
KW  - double-blind
KW  - fluvoxamine
KW  - placebo
KW  - clomipramine
KW  - multicenter
KW  - fluoxetine
KW  - pharmacotherapy
KW  - sertraline
KW  - trials
KW  - Psychiatry
L1  - internal-pdf://2122269773/Kotapati-2019-The Effectiveness of Selective S.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: IN7YQTimes Cited: 0Cited Reference Count: 43Kotapati, Vijaya Padma Khan, Ali M. Dar, Sara Begum, Guishan Bachu, Ramya Adnan, Mahwish Zubair, Aarij Ahmed, Rizwan A.0Frontiers media saLausanne
PY  - 2019
SP  - 14
T2  - Frontiers in Psychiatry
TI  - The Effectiveness of Selective Serotonin Reuptake Inhibitors for Treatment of Obsessive-Compulsive Disorder in Adolescents and Children: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000478898100001
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/437881/pubmed-zip/.versions/2/.package-entries/fpsyt-10-00523.pdf?sv=2015-12-11&amp;sr=b&amp;sig=MM4VaI5uRsYA%2B414BaAvTo2Vnkhko%2F2m6nJuwtUKDG8%3D&amp;se=2019-09-09T16%3A29%3A55Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyt-10-00523.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - &#039;&#039;BACKGROUND:** 
Medical procedures often evoke pain and anxiety in pediatric patients. Virtual reality (VR) is a relatively new intervention that can be used to provide distraction during, or to prepare patients for, medical procedures. This meta-analysis is the first to collate evidence on the effectiveness of VR on reducing pain and anxiety in pediatric patients undergoing medical procedures. 

**METHODS:** 
On April 25, 2018, we searched EMBASE, MEDLINE, CENTRAL, PubMed, Web of Science, and PsycINFO with the keywords &quot;VR&quot;, &quot;children,&quot; and &quot;adolescents&quot;. Studies that applied VR in a somatic setting with participants &lt;=21 years of age were included. VR was defined as a fully immersive 3-dimensional environment displayed in surround stereoscopic vision on a head-mounted display (HMD). We evaluated pain and anxiety outcomes during medical procedures in VR and standard care conditions. 

**RESULTS:** 
We identified 2889 citations, of which 17 met our inclusion criteria. VR was applied as distraction (n = 16) during venous access, dental, burn, or oncological care or as exposure (n = 1) before elective surgery under general anesthesia. The effect of VR was mostly studied in patients receiving burn care (n = 6). The overall weighted standardized mean difference (SMD) for VR was 1.30 (95% CI, 0.68-1.91) on patient-reported pain (based on 14 studies) and 1.32 (95% CI, 0.21-2.44) on patient-reported anxiety (based on 7 studies). The effect of VR on pediatric pain was also significant when observed by caregivers (SMD = 2.08; 95% CI, 0.55-3.61) or professionals (SMD = 3.02; 95% CI, 0.79-2.25). For anxiety, limited observer data were available. 

**CONCLUSIONS:** 
VR research in pediatrics has mainly focused on distraction. Large effect sizes indicate that VR is an effective distraction intervention to reduce pain and anxiety in pediatric patients undergoing a wide variety of medical procedures. However, further research on the effect of VR exposure as a preparation tool for medical procedures is needed because of the paucity of research into this field.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
AN  - 31136330
AU  - Eijlers,
AU  - R.
AU  - Utens,
AU  - E.
AU  - Staals,
AU  - L.
AU  - M.
AU  - de
AU  - Nijs,
AU  - P.
AU  - F.
AU  - A.
AU  - Berghmans,
AU  - J.
AU  - M.
AU  - Wijnen,
AU  - R.
AU  - M.
AU  - H.
AU  - Hillegers,
AU  - M.
AU  - H.
AU  - J.
AU  - Dierckx,
AU  - B.
AU  - Legerstee,
AU  - J.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1213/ANE.0000000000004165
L1  - internal-pdf://0288726616/Eijlers-2019-Systematic Review and Meta-analys.pdf
PY  - 2019
SP  - 23
T2  - Anesthesia &amp; Analgesia
TI  - Systematic Review and Meta-analysis of Virtual Reality in Pediatrics: Effects on Pain and Anxiety
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31136330
VL  - 05
ER  -
TY  - JOUR
AB  - Functional communication training (FCT) is an evidence-based practice used to mitigate challenging behavior by increasing functional communication skills. To increase the practicality and feasibility of FCT in natural settings, thinning schedules of reinforcement are typically programmed following FCT. In this review, we meta-analyzed 28 studies that incorporated a thinning schedule procedure following FCT for 51 children with intellectual and developmental disabilities ages 8 and younger. Using Tau-U, the results demonstrated overall moderate effect sizes for both challenging behavior and functional communication responses. Additionally, moderator analyses pertaining to participant characteristics, interventions, and study quality were conducted. Thinning procedures were most effective for children who had stronger communication repertoire. Implications for future research and practice are discussed.
AD  - (Muharib) Department of Curriculum and Instruction, Texas State University, 601 University Dr., San Marcos, TX 78666, United States (Alrasheed) Center for Behavioral Sciences, Irvine, CA, United States (Ninci) University of Hawaii at Manoa, Honolulu, HI, United States (Walker, Voggt) University of North Carolina at Charlotte, Charlotte, NC, United StatesR. Muharib, Department of Curriculum and Instruction, Texas State University, 601 University Dr., San Marcos, TX 78666, United States. E-mail: r_m806@txstate.edu
AN  - 2002712829
AU  - Muharib,
AU  - R.
AU  - Alrasheed,
AU  - F.
AU  - Ninci,
AU  - J.
AU  - Walker,
AU  - V.
AU  - L.
AU  - Voggt,
AU  - A.
AU  - P.
DA  - 01 Dec
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s10803-019-04191-x
DP  - Ovid Technologies
KW  - Children with intellectual and developmental disabilities
KW  - Functional communication training
KW  - Meta-analysis
KW  - Reinforcement schedule thinning
KW  - article
KW  - attention deficit disorder/di [Diagnosis]
KW  - behavior change
KW  - behavior disorder/di [Diagnosis]
KW  - behavior modification
KW  - child
KW  - communication skill
KW  - developmental disorder/di [Diagnosis]
KW  - effect size
KW  - evidence based practice
KW  - health care quality
KW  - human
KW  - intellectual impairment/di [Diagnosis]
KW  - interrater reliability
KW  - meta analysis
KW  - oppositional defiant disorder/di [Diagnosis]
KW  - practice guideline
KW  - priority journal
KW  - reinforcement
L1  - internal-pdf://2530848627/Muharib-2019.pdf
LA  - English
PY  - 2019
SP  - 4788-4806
T2  - Journal of Autism and Developmental Disorders
TI  - Thinning Schedules of Reinforcement Following Functional Communication Training for Children with Intellectual and Developmental Disabilities: A Meta-analytic Review
UR  - http://www.wkap.nl/journalhome.htm/0162-3257
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2002712829
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:31456100&amp;id=doi:10.1007%2Fs10803-019-04191-x&amp;issn=0162-3257&amp;isbn=&amp;volume=49&amp;issue=12&amp;spage=4788&amp;pages=4788-4806&amp;date=2019&amp;title=Journal+of+Autism+and+Developmental+Disorders&amp;atitle=Thinning+Schedules+of+Reinforcement+Following+Functional+Communication+Training+for+Children+with+Intellectual+and+Developmental+Disabilities%3A+A+Meta-analytic+Review&amp;aulast=Muharib&amp;pid=%3Cauthor%3EMuharib+R.%3C%2Fauthor%3E%3CAN%3E2002712829%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10803-019-04191-x
UR  - https://link.springer.com/content/pdf/10.1007%2Fs10803-019-04191-x.pdf
VL  - 49
ER  -
TY  - JOUR
AB  - **Background:**
Childhood conduct problems are a costly public health problem and are five times more common in socially disadvantaged groups than they are in advantaged groups. Untreated, conduct problems have a poor prognosis, with increasing gaps between socioeconomic groups, and high rates of subsequent criminality. Incredible Years is a high quality parenting programme for reducing conduct problems and is widely disseminated in Europe. Many trials have shown Incredible Years to be effective but the potential effects of parenting interventions on social inequality are unknown. Some behavioural interventions (eg, smoking cessation programmes), although beneficial overall, can widen inequality gaps. Because single trials and aggregate-level meta-analyses are ill equipped for examining differential intervention (moderator) effects, we pooled individual-level trial data to assess the effects of Incredible Years on social equity. 

**Methods:** 
We did a systematic review and individual participant data meta-analysis by searching CINAHL, Embase, Global Health, Medline, and PsycINFO, for studies published from inception to March 15, 2019. We also searched the Incredible Years website library and consulted with experts, including the European Incredible Years mentors&#039; network. We included data from all completed randomised trials of the Incredible Years parenting intervention in Europe that included children aged 1-12 years, including unpublished trials, without restriction on publication year or outcome measures. We included prevention (selective or universal) and treatment or indicated prevention trials (for children diagnosed or above the clinical cutoff for conduct problems). We excluded trials or conditions within trials that were not randomised, included additional non-parenting material (eg, child-focused interventions), or were abbreviated, non-standard versions of the usual Incredible Years intervention of 12-14 weekly sessions. We requested individual participant data from the study authors. The primary outcome was child conduct problems, assessed using the Eyberg Child Behavior Inventory Intensity (ECBI-I) scale. Moderators were analysed using multilevel modelling with multiple imputation. 

**Findings:** 
Of 15 European trials of Incredible Years parenting programmes (n=1696 children), individual participant data were unavailable for one trial and one trial did not assess the primary outcome. Children were aged 2-10 years (median 5.1), 492 (30%) of 1651 children were from an ethnic minority and 931 (58%) of 1614 were from low-income families. Families who received the Incredible Years intervention reported an overall reduction in child conduct problems (13.5 points on the ECBI-I scale, 95% CI 10.9-16.1). There were no differential effects by family disadvantage (indicated by poverty, lone parenthood, teenage parenthood, household joblessness, or low education), or ethnic minority status. 

**Interpretation:** 
We found no evidence for differential effects by social disadvantage, suggesting that Incredible Years is unlikely to widen socioeconomic inequalities in conduct problems. Furthermore, the programme might be an important tool for reducing social disparities and improving poor long-term outcomes in disadvantaged families because follow-up studies indicate that benefits persist. Clinicians and commissioners can be reassured that the programme is similarly effective for families from different backgrounds. (PsycINFO Database Record (c) 2019 APA, all rights reserved)
AN  - 2019-26954-001
AU  - Gardner,
AU  - F.
AU  - Leijten,
AU  - P.
AU  - Harris,
AU  - V.
AU  - Mann,
AU  - J.
AU  - Hutchings,
AU  - J.
AU  - Beecham,
AU  - J.
AU  - Bonin,
AU  - E.
AU  - M.
AU  - Berry,
AU  - V.
AU  - McGilloway,
AU  - S.
AU  - Gaspar,
AU  - M.
AU  - Seabra-Santos,
AU  - M.
AU  - J.
AU  - Orobio
AU  - de
AU  - Castro,
AU  - B.
AU  - Menting,
AU  - A.
AU  - Williams,
AU  - M.
AU  - Axberg,
AU  - U.
AU  - Morch,
AU  - W.
AU  - T.
AU  - Scott,
AU  - S.
AU  - Landau,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/S2215-0366%2819%2930162-2
L1  - internal-pdf://4227964676/Gardner-2019-Equity effects of parenting inter.pdf
PY  - 2019
SP  - 518-527
T2  - The Lancet Psychiatry
TI  - Equity effects of parenting interventions for child conduct problems: A pan-European individual participant data meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2019-26954-001
UR  - https://www.sciencedirect.com/science/article/abs/pii/S2215036619301622?via%3Dihub
VL  - 6
ER  -
TY  - JOUR
AB  - Dialectical Behavior Therapy (DBT) prioritizes suicidal behavior and other self-directed violence as the primary treatment targets, and has been demonstrated to reduce self directed violence in clinical trials. 

This paper synthesizes findings from controlled trials that assessed self-directed violence and suicidality, including suicide attempts, non suicidal self-injury (NSSI), suicidal ideation, and accessing psychiatric crisis services.

Eighteen controlled trials of DBT were identified. Random effects meta-analyses demonstrated that DBT reduced self-directed violence (d=-.324, 95% CI=-.471 to -.176), and reduced frequency of psychiatric crisis services (d=-.379, 95% CI=-.581 to -.176). 

There was not a significant pooled effect of DBT with regard to suicidal ideation (d=-.229, 95% CI=-.473 to .016). Our findings may reflect the prioritization of behavior over thoughts within DBT, and offer implications for clinical practice and future research concerning the implementation of DBT for acute suicidality.
AN  - WOS:000458095300006
AU  - DeCou,
AU  - C.
AU  - R.
AU  - Comtois,
AU  - K.
AU  - A.
AU  - Landes,
AU  - S.
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1016/j.beth.2018.03.009
L1  - internal-pdf://2788956199/DeCou-2019-Dialectical Behavior Therapy Is Eff.pdf
PY  - 2019
SP  - 60-72
T2  - Behavior Therapy
TI  - Dialectical Behavior Therapy Is Effective for the Treatment of Suicidal Behavior: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000458095300006
UR  - https://ac.els-cdn.com/S0005789418300492/1-s2.0-S0005789418300492-main.pdf?_tid=3f05af1e-fc1d-438d-8f20-615c13f2f3a7&amp;acdnat=1551877593_fe0faac4d62d351c7e0ae9edb13e25df
VL  - 50
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Faltering in linear growth and neurobehavioural development during early childhood are often assumed to have common causes because of their consistent association. This notion has contributed to a global focus on the promotion of nutrition during pregnancy and childhood to improve both conditions. Our aim was to assess whether effects of interventions on linear growth are associated with effects on developmental scores and to quantify these associations.

**METHODS:** 
In this systematic review and meta-analysis, we included randomised trials done during pregnancy and in children aged 0-5 years that reported effects of any intervention on length-for-age or height-for-age Z scores (LAZ or HAZ) and on any of the following outcomes: motor, cognitive or mental, language, and social-emotional or behavioural development. We searched MEDLINE (Ovid), CINAHL (EBSCO), and PsycINFO (EBSCO) from database inception to June 25, 2019. Study-level data were extracted and, when required, authors were contacted for missing information. We calculated weighted meta-regression coefficients of the association between standardised effect sizes of interventions on LAZ or HAZ and developmental outcome scores and calculated pooled effect sizes for different types of intervention.

**FINDINGS:** 
Of the 7207 studies identified, we included 75 studies with 122 comparisons between intervention and control groups and outcomes reported for 72 275 children. Across all interventions, effect sizes on LAZ or HAZ were significantly associated with effect sizes on social-emotional scores (beta 0.23, 95% CI 0.05 to 0.41; p=0.02), but not on cognitive (0.18, -0.36 to 0.72; p=0.51), language (0.12, -0.07 to 0.31; p=0.21), or motor development scores (0.23, -0.05 to 0.50; p=0.11). In studies that provided nutritional supplements, we observed positive significant pooled effect sizes on all five outcomes of LAZ or HAZ (effect size 0.05, 95% CI 0.01-0.09; p=0.01; n=50), cognitive or mental (0.06, 0.03-0.10; p&lt;0.01; n=38), language (0.08, 0.03-0.13; p=0.01; n=21), motor (0.08, 0.04-0.12; p&lt;0.01; n=41), and social-emotional (0.07, 0.02-0.12; p=0.01; n=20) scores. The effect sizes of nutritional supplementation on LAZ or HAZ scores were significantly associated with effect sizes on cognitive (beta 0.40, 95% CI 0.04-0.77; p=0.049) and motor (0.43, 0.11-0.75; p=0.01) scores. In the 14 interventions promoting responsive care and learning opportunities, the pooled effect size on LAZ or HAZ score was not significant (-0.01, 95% CI -0.07 to 0.05; p=0.74), but pooled effect sizes on cognitive, language, and motor scores were 4 to 5 times larger (range 0.38-0.48) than the pooled effect sizes of nutritional supplementation (0.05-0.08).

**INTERPRETATION:** 
In nutritional supplementation interventions, improvements in linear growth were associated with small improvements in child development, whereas nurturing and stimulation interventions had significant effects on child development but no effects on linear growth. The determinants of linear growth and neurodevelopment are only partly shared. To nurture thriving individuals and communities, interventions should specifically target determinants of neurodevelopment and not simply linear growth.

**FUNDING:** 
University of California Davis, US Department of Agriculture National Institute of Food and Agriculture.
AD  - Prado, Elizabeth L. Department of Nutrition, University of California Davis, Davis, CA, USA. Electronic address: elprado@ucdavis.edu.Larson, Leila M. Department of Medicine, University of Melbourne, Melbourne, VIC, Australia.Cox, Katherine. Department of Nutrition, University of California Davis, Davis, CA, USA.Bettencourt, Kory. Department of Nutrition, University of California Davis, Davis, CA, USA.Kubes, Julianne N. Emory University Rollins School of Public Health, Atlanta, GA, USA.Shankar, Anuraj H. Eijkman-Oxford Clinical Research Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
AN  - 31537370
AU  - Prado,
AU  - E.
AU  - L.
AU  - Larson,
AU  - L.
AU  - M.
AU  - Cox,
AU  - K.
AU  - Bettencourt,
AU  - K.
AU  - Kubes,
AU  - J.
AU  - N.
AU  - Shankar,
AU  - A.
AU  - H.
DA  - Oct
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/S2214-109X(19)30361-4
DP  - Ovid Technologies
J2  - Lancet Glob Health
L1  - internal-pdf://2743265863/Prado-2019-Do effects of early life interventi.pdf
LA  - English
N1  - Prado, Elizabeth LLarson, Leila MCox, KatherineBettencourt, KoryKubes, Julianne NShankar, Anuraj HS2214-109X(19)30361-4
PY  - 2019
SP  - e1398-e1413
T2  - The Lancet Global Health
TI  - Do effects of early life interventions on linear growth correspond to effects on neurobehavioural development? A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31537370
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31537370&amp;id=doi:10.1016%2FS2214-109X%2819%2930361-4&amp;issn=2214-109X&amp;isbn=&amp;volume=7&amp;issue=10&amp;spage=e1398&amp;pages=e1398-e1413&amp;date=2019&amp;title=The+Lancet+Global+Health&amp;atitle=Do+effects+of+early+life+interventions+on+linear+growth+correspond+to+effects+on+neurobehavioural+development%3F+A+systematic+review+and+meta-analysis.&amp;aulast=Prado&amp;pid=%3Cauthor%3EPrado+EL%3C%2Fauthor%3E%3CAN%3E31537370%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/286970/1-s2.0-S2214109X19X0011X/1-s2.0-S2214109X19303614/main.pdf?X-Amz-Security-Token=AgoJb3JpZ2luX2VjEC8aCXVzLWVhc3QtMSJGMEQCIAFDG%2FLsQUFW1NYQP1m7%2B97bqygl6FX6O6emJT1f1JQQAiBrBUUg0C5UkX8zDahaoJO67WLOZRwcSY6VqJiX%2FInFgyraAwgoEAIaDDA1OTAwMzU0Njg2NSIMSG5AMZDJytl%2BrLXcKrcDCeNoZRVCvsl3nI%2Fw4W%2B6uu2dCkO8vi0znXYBarA9sbqzjWbUSTqC4xDEmy9WZ37d5mt790vc1pkdXstQgtwH41y6B4HXdJ4jAsZ3pDWrE9rI7%2FSrOMK4Bnls41Qw3wvXuxnC2rlZNINcShm0PWoidrstX%2BNwLK0JmzmKel%2FtK7XbGVA0bURBy2x%2B9P%2FppjQQwALM7wHViDk8wjs0ZeNKSHhgrCaFdruZYQpYAk4C3DHEKVoFICiQcGG1ldlUK9T9P8nvhHsCR2mIvU8atZ0SrQCqujOAiG%2Bk8HFNtim0no%2Bsd77i5z10cU9tpPtSEPYybEca2hrH07XLvwG96hHNJuGq2c3aS%2BdFeJ7iVP3wKyKLbeOV3Vk1QpFjkVeSdCG9%2B8wNKYO5lVLH72Q%2B8uFcgwk%2FN4bGWwd0XuKkcKpiTpuBktOx66mh2hIsGnTEgNnOjbmieOQ55YFcFQLrLR9P%2FdEcbezcjsWzVyZfuDKt0I4Zg21uTeJNX9Pd2nHz3rbH24urIcx8oWkm%2FUi2q85bBkKt6VZjEj3v2X29Ljqyaf1%2BLxg0MCmfzXMrh6t4s7XFLXYwG8GMtDC8rZDtBTq1AeJZUp8Ll7pZIujHmDJjLg5AGCw3BtQxboiYY4AsOnm4cN1hfLFUF3QZYxw9z2I2WER%2FHAExLJhrixahKv%2BPuv91dXMiqn2gtIyMbTpDGkH1%2Fj8D4DCT%2F2uBE8Uje8yRY%2BTxzaZuLvB1n%2F8zhlk%2FN%2BdjNvZnteV2%2FR7zsyZd%2FaieBMwfSEQ0RJN3oe6bRt5loxqTrKQVfeKGBoUD9jhILWWjlEkziLJvrl1pi3VUNZUJd76bH34%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20191014T081333Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYTMJPLR2E%2F20191014%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=f744978d8f89e73dc7deb5e28ff84e7be6e520ff2c6b5e73271f3b4e0c321fae&amp;hash=6c31c1f6d49fe20e10f293680c044aa429ce23119401f5b3f02e7c8c175c67b6&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S2214109X19303614&amp;tid=spdf-fee6786e-4ff9-4fa2-813f-8305f9642946&amp;sid=a93642a63b50a849e3790de160a6d7e70438gxrqb&amp;type=client
VL  - 7
ER  -
TY  - JOUR
AB  - In children under 5, a hemoglobin (Hb) cutoff of 11 g/dL is recommended by the World Health Organization to define anemia, yet few studies have examined whether this cut point accurately coincides with negative functional consequences. This systematic review and meta-analysis of iron intervention and observational studies aimed to clarify the consequences of low Hb concentration in children under age 5 years on growth, development, and chronic disease (functional outcomes) across the full range of Hb values.

A literature search returned 5049 studies; of these, 56 intervention and 20 observational studies fit the inclusion criteria. Among iron supplementation trials, a metaregression indicated significant associations between intervention effects on Hb and their effects on motor and mental development. For each 1 standard deviation (SD) increase in Hb, motor scores increased by 0.28 SD and mental scores increased by 0.24 SD. Iron supplementation trials among children with lower Hb concentrations at baseline showed stronger associations between their effects on Hb and their effects on mental development (P-interaction = 0.008). Heterogeneity among observational studies precluded calculation of pooled associations between Hb and functional outcomes. 

Available evidence was not able to establish an inflection point at which decreasing Hb begins to be associated with negative functional outcomes. Future research is needed to examine associations of Hb with growth and development in populations with varying levels of Hb, inflammation, and in different ages and settings.
AN  - 31157417
AU  - Larson,
AU  - L.
AU  - M.
AU  - Kubes,
AU  - J.
AU  - N.
AU  - Ramirez-Luzuriaga,
AU  - M.
AU  - J.
AU  - Khishen,
AU  - S.
AU  - H.
AU  - Shankar
AU  - A
AU  - Prado,
AU  - E.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/nyas.14105
L1  - internal-pdf://4190150904/Larson-2019-Effects of increased hemoglobin on.pdf
PY  - 2019
SP  - 03
T2  - Annals of the New York Academy of Sciences
TI  - Effects of increased hemoglobin on child growth, development, and disease: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31157417
UR  - https://nyaspubs.onlinelibrary.wiley.com/doi/pdf/10.1111/nyas.14105
VL  - 03
ER  -
TY  - JOUR
AB  - Given the recent rise in adolescent mental health issues, many researchers have turned to school-based mental health programs as a way to reduce stress, anxiety, and depressive symptoms among large groups of adolescents. The purpose of the current systematic review and meta-analysis is to identify and evaluate the efficacy of school-based programming aimed at reducing internalizing mental health problems of adolescents. A total of 42 articles, including a total of 7310 adolescents, ages 11-18, met inclusion for the meta-analyses. Meta-analyses were completed for each of the three mental health outcomes (stress, depression, and anxiety) and meta-regression was used to determine the influence of type of program, program dose, sex, race, and age on program effectiveness. 

Overall, stress interventions did not reduce stress symptoms, although targeted interventions showed greater reductions in stress than universal programs. Overall, anxiety interventions significantly reduced anxiety symptoms, however higher doses may be necessary for universal programs. Lastly, depression interventions significantly reduced depressive symptoms, but this reduction was moderated by a combination of program type, dose, race, and age group. Although, school-based programs aimed at decreasing anxiety and depression were effective, these effects are not long-lasting. Interventions aimed at reducing stress were not effective, however very few programs targeted or included stress as an outcome variable. Implications for practice, policy and research are discussed.
AD  - Feiss, Robyn. College of Education School of Kinesiology, Auburn University, 301 Wire Rd, Auburn, AL, 36849, USA. rsf0012@auburn.edu.Dolinger, Sarah Beth. College of Education School of Kinesiology, Auburn University, 301 Wire Rd, Auburn, AL, 36849, USA.Merritt, Monaye. College of Education School of Kinesiology, Auburn University, 301 Wire Rd, Auburn, AL, 36849, USA.Reiche, Elaine. College of Education School of Kinesiology, Auburn University, 301 Wire Rd, Auburn, AL, 36849, USA.Martin, Karley. College of Education School of Kinesiology, Auburn University, 301 Wire Rd, Auburn, AL, 36849, USA.Yanes, Julio A. Department of Psychology, Auburn University, 208 Thatch Hall, Auburn, AL, 36849, USA.Yanes, Julio A. Auburn University Magnetic Resonance Imaging Research Center, Auburn University, 560 Devall Dr, Auburn, AL, 36832, USA.Thomas, Chippewa M. Department of Special Education, Rehabilitation and Counseling, Auburn University, 351 W Thach Concourse, Auburn, AL, 36849, USA.Thomas, Chippewa M. Office of Faculty Engagement-University Outreach, Auburn University, 213 Samford Hall, Auburn, AL, 36849, USA.Pangelinan, Melissa. College of Education School of Kinesiology, Auburn University, 301 Wire Rd, Auburn, AL, 36849, USA.
AN  - 31346924
AU  - Feiss,
AU  - R.
AU  - Dolinger,
AU  - S.
AU  - B.
AU  - Merritt,
AU  - M.
AU  - Reiche,
AU  - E.
AU  - Martin,
AU  - K.
AU  - Yanes,
AU  - J.
AU  - A.
AU  - Thomas,
AU  - C.
AU  - M.
AU  - Pangelinan,
AU  - M.
DA  - Jul 26
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10964-019-01085-0
DP  - Ovid Technologies
J2  - J Youth Adolesc
L1  - internal-pdf://0414728433/Feiss-2019.pdf
LA  - English
N1  - Using Smart Source ParsingJulFeiss, RobynDolinger, Sarah BethMerritt, MonayeReiche, ElaineMartin, KarleyYanes, Julio AThomas, Chippewa MPangelinan, Melissa
PY  - 2019
SP  - 26
T2  - Journal of Youth &amp; Adolescence
TI  - A Systematic Review and Meta-Analysis of School-Based Stress, Anxiety, and Depression Prevention Programs for Adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31346924
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31346924&amp;id=doi:10.1007%2Fs10964-019-01085-0&amp;issn=0047-2891&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2019&amp;title=Journal+of+Youth+%26+Adolescence&amp;atitle=A+Systematic+Review+and+Meta-Analysis+of+School-Based+Stress%2C+Anxiety%2C+and+Depression+Prevention+Programs+for+Adolescents.&amp;aulast=Feiss&amp;pid=%3Cauthor%3EFeiss+R%3C%2Fauthor%3E%3CAN%3E31346924%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10964-019-01085-0
VL  - 26
ER  -
TY  - JOUR
AB  - This meta-analysis examined the effects of family-school interventions on children&#039;s social-behavioral competence and mental health. One hundred and seventeen group design studies yielding 592 effect sizes constituted the current sample. Random effects models were estimated when calculating each pooled effect size estimate, and mixed effects models were calculated for each moderator analysis. The analyses yielded significant effects of family-school interventions on children&#039;s social-behavioral competence and mental health ( delta . s = 0.332 and 0.391, respectively). Effects on children&#039;s mental health were moderated by race/ethnicity (effects were larger for African American students) and locale (effects were smaller in urban settings relative to nonurban/rural settings). Components found to be significantly related to positive outcomes included both interpersonal, relational processes (i.e., communication, collaboration, and parent-teacher relationship) and tangible, structural elements (i.e., home-based involvement, behavioral supports). These findings indicate the benefits of family-school interventions and have implications for tailoring interventions to family characteristics and communities. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
AD  - NatashaSheridan, Susan M.: ssheridan2@unl.edu; Smith, Tyler E.: smithtyle@missouri.edu; Kim, Elizabeth Moorman: elizabeth.kim@emory.edu; Beretvas, S. Natasha: tberetvas@austin.utexas.edu; Park, Sunyoung: 1125sunny1987@gmail.comSheridan, Susan M.: University of Nebraska-Lincoln, Center for Research on CYFS, 162 WHIT, Lincoln, NE, US, 68588, ssheridan2@unl.eduSheridan, Susan M.: University of Nebraska-Lincoln, Center for Research on CYFS, Lincoln, NE, USSmith, Tyler E.: University of Nebraska-Lincoln, Lincoln, NE, USKim, Elizabeth Moorman: University of Nebraska-Lincoln, Lincoln, NE, USBeretvas, S. Natasha: University of Texas-Austin, Austin, TX, USPark, Sunyoung: University of Texas-Austin, Austin, TX, US
AN  - 2019-15053-004
AU  - Sheridan,
AU  - Susan
AU  - M.
AU  - Smith,
AU  - Tyler
AU  - E.
AU  - Kim,
AU  - Elizabeth
AU  - Moorman
AU  - Beretvas,
AU  - S.
AU  - Park,
AU  - Sunyoung
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.3102/0034654318825437
DP  - Ovid Technologies
KW  - effect size, families, learning environments, meta-analysis, parents and families, social processes/development
KW  - *Family
KW  - *Intervention
KW  - *Mental Health
KW  - *Schools
KW  - *Social Functioning
KW  - Effect Size (Statistical)
KW  - Emotional Regulation
KW  - Learning Environment
KW  - Educational Psychology [3500]
KW  - Human
L1  - internal-pdf://2044627347/Sheridan-2019.pdf
LA  - English
M3  - Meta Analysis
PY  - 2019
SP  - 296-332
T2  - Review of Educational Research
TI  - A meta-analysis of family-school interventions and children&#039;s social-emotional functioning: Moderators and components of efficacy
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc17&amp;AN=2019-15053-004
UR  - https://journals.sagepub.com/doi/10.3102/0034654318825437
UR  - https://journals.sagepub.com/doi/pdf/10.3102/0034654318825437
VL  - 89
ER  -
TY  - JOUR
AB  - Sensory integration is one of the most highly utilized interventions in autism, however, a lack of consensus exists regarding its evidence base. An increasing number of studies are investigating the effectiveness of this approach. This study used the Council for Exceptional Children (CEC) Standards for Evidence-based Practices in Special Education to evaluate the effectiveness research from 2006 to 2017 on Ayres Sensory Integration (ASI) intervention for children with autism. 

A systematic review was conducted in three stages. Stage 1 involved an extensive database search for relevant studies using search terms related to sensory integration and autism, interventions suggesting a sensory integration approach, and high-quality study designs. Searches yielded 19 studies that were evaluated in Stage 2. 

Six of these met inclusion criteria of being peer-reviewed, written in English, description of intervention this is consistent with ASI intervention, and comparison group design or single subject method employed. Prior to analysis using CEC standards, three articles were excluded because intervention details were not consistent with the core principles of ASI, or because of major methodological flaws. 

In Stage 3, the remaining three studies were rated using the CEC quality indicators and standards for an evidence-based practice. Two randomized controlled trials respectively met 100% and 85% of the CEC criteria items. One additional study met more than 50% of the criteria. Based on CEC criteria, ASI can be considered an evidence-based practice for children with autism ages 4-12 years old. 

Autism Research 2019, 12: 6-19. &copy; 2018 The Authors. 
Autism Research published by International Society for Autism Research and Wiley Periodicals, Inc. 

**LAY SUMMARY: **
Ayres Sensory Integration intervention is one of the most frequently requested and highly utilized interventions in autism. This intervention has specific requirements for therapist qualifications and the process of therapy. This systematic review of studies providing Ayres Sensory Integration therapy to children with autism indicates that it is an evidence-based practice according to the criteria of the Council for Exceptional Children.
AN  - 30548827
AU  - Schoen,
AU  - S.
AU  - A.
AU  - Lane,
AU  - S.
AU  - J.
AU  - Mailloux,
AU  - Z.
AU  - May-Benson,
AU  - T.
AU  - Parham,
AU  - L.
AU  - D.
AU  - Smith
AU  - Roley,
AU  - S.
AU  - Schaaf,
AU  - R.
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/aur.2046
L1  - internal-pdf://1486009572/Schoen-2019-A systematic review of ayres senso.pdf
PY  - 2019
SP  - 6-19
T2  - Autism research : Official Journal of the International Society for Autism Research
TI  - A systematic review of ayres sensory integration intervention for children with autism
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30548827
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1002/aur.2046
VL  - 12
ER  -
TY  - JOUR
AB  - Mental health problems are common in children and adolescents, yet evidence-based treatments are hard to access. Self-help interventions can increase such access. 
The aim of this paper was to conduct a systematic review and meta-analysis of the use of guided and unguided self-help for children and young people with symptoms of common mental health disorders. In contrast to previous reviews of self-help in children, all types of self-help and multiple mental health disorders were investigated in order to increase power to investigate potential moderators of efficacy.

Importantly, studies with control arms as well as those comparing against traditional face-to-face treatments were included. Fifty studies (n = 3396 participants in self-help/guided self-help conditions) met the inclusion criteria.
AN  - 30775782
AU  - Bennett,
AU  - S.
AU  - D.
AU  - Cuijpers,
AU  - P.
AU  - Ebert,
AU  - D.
AU  - D.
AU  - McKenzie
AU  - Smith,
AU  - M.
AU  - Coughtrey,
AU  - A.
AU  - E.
AU  - Heyman,
AU  - I.
AU  - Manzotti,
AU  - G.
AU  - Shafran,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.13010
L1  - internal-pdf://0925221303/Bennett-2019-Practitioner Review_ Unguided and.pdf
PY  - 2019
SP  - 18
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Practitioner Review: Unguided and guided self-help interventions for common mental health disorders in children and adolescents: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30775782
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcpp.13010
VL  - 18
ER  -
TY  - JOUR
AB  - **Aim:** 
This paper aims to investigate the extent to which mindfulness-based interventions serve to reduce anxiety in children and adolescents. A heterogeneous sample was used, including clinical and non-clinical population. 

**Method(s):** 
A literature search of controlled intervention studies published up to December 31, 2016, was carried out in PubMed, Lilacs, Cochrane, Embase, PsycInfo, Opengrey and Teseo databases. The effect size was calculated by Cohen&#039;s d. The Cochran Q statistic and the I&lt;sup&gt;2&lt;/sup&gt; index were used for the study of heterogeneity. An analysis was conducted using the random effects model. 

**Result(s):** 
829 articles were identified, of which 18 were finally selected. Of these, only three had statistically significant effect sizes. The overall combined result obtained was.013, but it did not result statistically significant (CI95% [-.102,.128].) The Q statistic was statistically significant (Q [18] = 28.497, P =. 39) and the I&lt;sup&gt;2&lt;/sup&gt; index was 40.34%, indicating a moderate heterogeneity. 

**Conclusion(s):** 
This meta-analysis did not obtain statistically significant results that could provide conclusions. In general, the studies analysed are small, of low power and have a marked heterogeneity, which implies that the findings are provisional and need to be supported by more robust studies. Although it cannot be ruled out that mindfulness-based interventions are not effective in the infant-juvenile population, it is also possible that this effect could not be detected due to the limited number of available studies. Larger investigations are needed, with sufficient statistical power and designs that control the variables potentially moderating, to establish clear conclusions. Copyright &copy; 2019 John Wiley &amp; Sons Australia, Ltd
AN  - 628480461
AU  - Ruiz-Iniguez,
AU  - R.
AU  - German,
AU  - M.
AU  - A.
AU  - S.
AU  - Burgos-Julian,
AU  - F.
AU  - A.
AU  - Diaz-Silveira,
AU  - C.
AU  - Montero,
AU  - A.
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/eip.12849
L1  - internal-pdf://1868426271/Ruiz-Iniguez-2019-Effectiveness of mindfulness.pdf
PY  - 2019
T2  - Early Intervention in Psychiatry.
TI  - Effectiveness of mindfulness-based interventions on anxiety for children and adolescents: A systematic review and meta-analysis
UR  - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1751-7893
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/eip.12849
ER  -
TY  - JOUR
AB  - **Innledning** 
Regjeringen har utviklet en strategi for foreldrestøtte. Målet er å forebygge utvikling av problemer hos barn, gi tryggere foreldre og bidra til at foreldre med særlige behov får nødvendig hjelp, slik at risiko for omsorgssvikt reduseres. På sikt vil denne forebyggende innsatsen være samfunnsøkonomisk lønnsom. Barne-, ungdoms- og familiedirektoratet (Bufdir) ønsker i økende grad å tilby sine tjenester digitalt og lanserte i 2016 en hjemmeside med foreldreveiledning. Denne siden skal videreutvikles, og andre digitale tiltak skal vurderes. På denne bakgrunn bestilte Bufdir en systematisk oversikt over effekter av og erfaringer med digitale tiltak for foreldrestøtte. 

**Metode** 
Vi utførte en systematisk oversikt i tråd med metodehåndboken fra område for helsetjenester, Folkehelseinstituttet. Vi gjorde et litteratursøk i relevante databaser og grå litteratur som ble avsluttet i oktober 2018. For spørsmål om både effekt og erfaring skulle systematiske oversikter og primærstudier inkluderes dersom de sammenlignet digitale tiltak for foreldrestøtte med ansikt-til-ansikt-tiltak eller ingen tiltak. Rapporterte effektmål var samspill, kommunikasjon, relasjon, bruk av &laquo;oppdragervold&raquo; og kostnadseffektivitet. I kvalitative studier var relevante tema deltakernes erfaringer med digitale foreldrestøttetiltak. To forskere gikk gjennom alle titler og sammendrag og deretter aktuelle artikler i fulltekst, for å vurdere relevans i henhold til inklusjonskriteriene. Kun primærstudier møtte kriteriene. To forskere vurderte de inkluderte studiene for mulig risiko for skjevheter (for studier av effekt) eller metodologisk sterke og svake sider (for studier av erfaring). Vi sammenstilte studiene, formulerte funn og vurderte tilliten til funnene ved hjelp av GRADE (effekt) og GRADE-CERQual (erfaring). 

**Resultat** 
Vi inkluderte 36 unike studier av 35 tiltak: 30 studier av effekt (28 randomiserte kontrollerte studier og to ikke-randomiserte kontrollerte studier, med totalt over 6000 deltakere) og seks studier av erfaring. Tjueen studier var fra USA, ni var fra Australia og &eacute;n studie fra hver av landene Canada, England, Finland, Sverige, Tyskland og Wales. Studiene ble publisert mellom 2007 og 2018 (de kvantitative er publisert etter 2010). Tretti av de 35 tiltakene var onlinetiltak, mens to var eposttiltak, ett var telefontiltak, ett var apptiltak og ett var podkasttiltak. Tiltakene var ulike med hensyn til flere aspekter i tillegg til tiltakets digitale format: settingen for tiltaket, omfanget av tiltaket, tiltakets faglig innretning, målgruppen tiltaket er rettet mot, samt hvordan endring måles. Av den grunn har vi formulert relativt overordnede funn. Majoriteten av tiltakene var selektive, det vil si rettet mot familier med kjente risikofaktorer (i hovedsak vanskeligstilte familier med dårlig økonomi eller bosatt i et fattig nabolag). Nesten like mange tiltak var indikative, det vil si rettet mot foreldre med barn med tegn på begynnende problemer (primært atferdsproblemer men også psykiske problemer). Et lite antall av tiltakene var universelle, altså rettet mot foreldre generelt, uavhengig av risiko. Vi har foretatt seks sammenligninger &ndash; basert på digitalt format og omfang &ndash; og en samlet vurdering av erfaringer. Utfall er sammenslått til foreldreatferd. Vår tillit til resultatene er inkludert i formuleringen av funn. 

Effekt av onlinetiltak 1-6 sesjoner sammenlignet med ingen tiltak 
Ti studier sammenlignet onlinetiltak bestående av 1-6 sesjoner, med det å ikke motta noe tiltak &ndash; enten tjenester som vanlig eller stå på en venteliste og få tilgang til det aktuelle tiltaket etter at tiltaksgruppa var ferdig og utfallene målt. Tiltakene var av varierende omfang og varighet men relativt korte. Det korteste tiltaket besto av &eacute;n sesjon &aacute; 10 min; det lengste var på seks sesjoner &aacute; 20-30 min over åtte uker. I åtte av ti tiltak var det ingen tilbud om veiledning fra en profesjonell i programmet. Tre tiltak var rettet mot foreldre av småbarn 1-5 år, fire tiltak var rettet mot foreldre av skolebarn 5-12 år, og tre tiltak var rettet mot foreldre av ungdom 13-18 år. Vi fant at trolig gir onlinetiltak med 1-6 sesjoner (for familier med småbarn, skolebarn, ungdom) med begrenset veiledning i hovedsak mer hensiktsmessig foreldreatferd, sammenlignet med ingen tiltak. 

Effekt av onlinetiltak 7-12 sesjoner sammenlignet med ingen tiltak 
Femten studier sammenlignet onlinetiltak bestående av 7-12 sesjoner, med det å ikke få noe tiltak, dvs. stå på venteliste, få tilgang til en nettside med relevant informasjon, eller tjenester som vanlig. De fleste programmene inneholdt ukentlige sesjoner over 8- 10 uker. Ni av 15 tiltak tilbød veiledning, seks av disse ukentlig veiledning på telefon. To tiltak var rettet mot foreldre med babyer 0-1 år, fem tiltak var rettet mot foreldre av småbarn 1-5 år, tre tiltak var rettet mot foreldre av skolebarn 5-12 år, og fem tiltak var rettet mot foreldre av ungdom 13-18 år. Vi fant at trolig gir onlinetiltak med 7-12 sesjoner (for familier med baby, småbarn, skolebarn, ungdom), ofte med veiledning, i hovedsak mer hensiktsmessig foreldreatferd, sammenlignet med ingen tiltak. 

Effekt av onlinetiltak sammenlignet med ansikt-til-ansikt-tiltak 
Fire studier sammenlignet onlinetiltak med tiltak som ble gitt ansikt-til-ansikt. I to av studiene valgte deltakerne selv om de skulle få online- eller ansikt-til-ansikt-tiltak (i de resterende var det tilfeldig fordeling på gruppene). Onlinetiltakene var av ulik lengde (1-10 sesjoner) og uten veiledning, mens kontrolltiltakene var veiledede grupper av tilsvarende lengde. Vi fant ingen klare forskjeller mellom onlinetiltak og ansikt-til-ansikttiltak når det gjelder effekter på foreldreatferd, men resultatene er noe usikre. 

Effekt av eposttiltak sammenlignet med ingen tiltak 
To studier undersøkte tiltak basert på eposter. Det ene tiltaket gikk over fire uker mens det andre gikk over 12 uker og omfattet i tillegg ukentlig veiledning per telefon. Begge studier sammenlignet eposttiltak med ingen tiltak; henholdsvis venteliste og tjenester som vanlig. Vi fant at muligens gir eposttiltak (for familier med barn, ungdom) ingen eller liten effekt på foreldreatferd, sammenlignet med ingen tiltak. 

Effekt av apptiltak sammenlignet med ingen tiltak
&Eacute;n studie undersøkte en applikasjon beregnet på smarttelefoner. Kontrollgruppen fikk ingen tiltak. Vi vet ikke om apptiltak for foreldre barn 8-12 år gir noen effekt på foreldreatferd, sammenlignet med ingen tiltak.

Effekt av podkasttiltak sammenlignet med ingen tiltak 
&Eacute;n studie undersøkte et tiltak i form av en podkast, beregnet til å lytte på fra telefon, pc eller annen digital plattform. Kontrollgruppen fikk ingen tiltak. Vi vet ikke om podkasttiltak for foreldre av barn 2-10 år har noen effekt på foreldreatferd, sammenlignet med ingen tiltak. 

Foreldres erfaringer med digitale tiltak for foreldrestøtte 
Seks studier av foreldres erfaringer med digitale tiltak for foreldrestøtte viste at deltakere i online- og telefontiltak satte pris på fleksibiliteten og anonymiteten i digitale tiltak. I onlinetiltak ble eksempelvideoene trukket frem som viktige for læring, særlig når disse speilet deltakernes kultur og personlige stil. Tiltak som tilbød veiledning ble verdsatt for faglig støtte og individuell tilrettelegging. Deltakere i flere tiltak vektla anerkjennelse og trygghet som grunnleggende for tillit og god læring. 

**Diskusjon** 
Det var stor bredde i tiltakenes omfang og intensitet, og basert på våre sammenstillinger har vi ikke grunnlag for å si at noen typer gir flere ønskede endringer enn andre typer tiltak, men de er bedre enn ingen tiltak. Onlinetiltakene har best dokumentert effekt, men disse er også mest studert. Også når det gjelder veiledning var det mange ulike varianter, men vi har ikke grunnlag for å trekke slutninger. Imidlertid finner vi i de kvalitative studiene at i onlinetiltak som tilbød veiledning, satte deltakerne pris på den faglige kompetansen samt muligheten for individuell tilpasning. De fleste programmene var kognitiv-atferdsrettede og la vekt på å lære foreldrene ferdigheter i kommunikasjon, grensesetting/disiplin, ros og konfliktløsning. Noen programmer la opp til å lære den rette måten å gjøre ting på, gjerne via flervalgstesting. Andre oppmuntret i større grad til refleksjon og utprøving. Tiltakene var i hovedsak rettet mot vanskeligstilte familier eller familier med barn med atferdsproblemer. Det er ikke sikkert at disse forskjellene var vesentlige for innholdet i programmet og dermed for vurdering av effekter og erfaringer. Noen tiltak inngikk også i begge kategorier. Imidlertid besto sistnevnte utvalg av mer ressurssterke familier, som kanskje kan tilsi at de nyttiggjorde seg tiltakene bedre. Kun &eacute;n studie målte kostnadseffektivitet. 

**Konklusjon** 
I denne oversikten har vi funnet at 25 onlinetiltak av kortere eller lengre varighet, med eller uten veiledning, trolig gir mer hensiktsmessig foreldreatferd, sammenlignet med ingen tiltak. Kvalitative studier viste positive erfaringer med fleksibilitet og anonymitet, samt veiledning og individuell og kulturell tilpasning. Det er behov for mer forskning på andre digitale format og flere studier som sammenligner digitale og ansikt-til-ansikt-tiltak. Videre trengs mer forskning på fedre og på ulike samfunnsgrupper &ndash; som innvandrere. Flere gode kvalitative studier er ønskelig.
AU  - Nøkleby,
AU  - H.
AU  - Flodgren,
AU  - G.
AU  - Langøien,
AU  - L.
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/digitale-tiltak-for-foreldrestotte-rapport-2019.pdf
PY  - 2019
T2  - Folkehelseinstituttet
TI  - Digitale tiltak for foreldrestøtte: en systematisk oversikt over effekter og erfaringer
ER  -
TY  - JOUR
AB  - **Importance:** 
Evidence on the titration of stimulant medications for attention-deficit/hyperactivity disorder (ADHD) is lacking. However, this lack of evidence has not prevented medication guidelines from specifying apparently arbitrary dose limitations, which could discourage clinicians from titrating methylphenidate to higher and, perhaps for some patients, more efficacious doses. 

**Objective(s):** 
To determine the evidence on dose titration and adverse events associated with dose titration of stimulants for ADHD. 

**Data Sources:** 
MEDLINE from 1946, Embase from 1974, and PsycINFO from 1806 through April 1, 2019, were searched to identify relevant articles. 

**Study Selection:** 
The inclusion criteria were that (1) the study was conducted on children up to 18 years of age; (2) children had a diagnosis of ADHD according to the Diagnostic and Statistical Manual of Mental Disorders, or hyperkinetic disorder according to the International Classification of Diseases codes; and (3) the dose of methylphenidate was determined by titration. 

**Data Extraction and Synthesis:** 
The PRISMA guidelines for abstracting data and assessing data quality and validity were followed. Quality assessment was undertaken using the Jadad scoring system. Statistical analysis was undertaken using a random-effects model. 

**Main Outcomes and Measures:** 
The outcomes of interest were (1) the doses used in published clinical trials, (2) the clinical justification given by researchers for their selected dose range, and (3) the adverse effects associated with methylphenidate when the dose is established by titration. 

**Result(s):** 
A total of 11 randomized clinical trials and 38 cohort studies were analyzed. The randomized clinical trials involved 1304 participants treated with methylphenidate and 887 controls; the 38 cohort studies included 5524 participants. Maximum doses of methylphenidate ranged from 0.8 to 1.8 mg/kg/d. Some studies detailed their method of titration, including starting dose, titration interval, increment dose, and maximum dose. Not all of these studies reported justification for the chosen dose range. Common adverse effects of methylphenidate included insomnia (odds ratio, 4.66; 95% CI, 1.99-10.92; P &lt;.001), anorexia (5.11 higher than for those who took placebo; 95% CI, 1.99-13.14; P &lt;.001), abdominal pain (1.9 times more likely; 95% CI, 0.77-4.77; P =.16), and headache (14% of participants; 95% CI, 10%-20%; P &lt;.001). 

**Conclusions and Relevance:** 
A range of maximum doses for methylphenidate was recommended in clinical studies; no discernable scientific justification for any particular dose was given. Reports of life-threatening adverse events were absent; further studies of the efficacy, tolerability, and safety of methylphenidate titrated purely on clinical grounds, without reference to any set maximum dose, are needed. Copyright &copy; 2019 American Medical Association. All rights reserved.
AN  - 628015097
AU  - Ching,
AU  - C.
AU  - Eslick,
AU  - G.
AU  - D.
AU  - Poulton,
AU  - A.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1001/jamapediatrics.2019.0905
L1  - internal-pdf://0870030358/Ching-2019-Evaluation of Methylphenidate Safet.pdf
PY  - 2019
T2  - JAMA Pediatrics.
TI  - Evaluation of Methylphenidate Safety and Maximum-Dose Titration Rationale in Attention-Deficit/Hyperactivity Disorder: A Meta-analysis
UR  - http://archpedi.jamanetwork.com/issues.aspx
UR  - https://jamanetwork.com/journals/jamapediatrics/articlepdf/2734742/jamapediatrics_ching_2019_oi_190018.pdf
ER  -
TY  - JOUR
AB  - **Background**
Alcohol use in young people is a risk factor for a range of short‐ and long‐term harms and is a cause of concern for health services, policy‐makers, youth workers, teachers, and parents.

**Objectives**
To assess the effectiveness of universal, selective, and indicated family‐based prevention programmes in preventing alcohol use or problem drinking in school‐aged children (up to 18 years of age).

Specifically, on these outcomes, the review aimed:

&bull; to assess the effectiveness of universal family‐based prevention programmes for all children up to 18 years (&lsquo;universal interventions&rsquo;);

&bull; to assess the effectiveness of selective family‐based prevention programmes for children up to 18 years at elevated risk of alcohol use or problem drinking (&lsquo;selective interventions&rsquo;); and

&bull; to assess the effectiveness of indicated family‐based prevention programmes for children up to 18 years who are currently consuming alcohol, or who have initiated use or regular use (&lsquo;indicated interventions&rsquo;).

**Search methods**
We identified relevant evidence from the Cochrane Central Register of Controlled Trials (CENTRAL), in the Cochrane Library, MEDLINE (Ovid 1966 to June 2018), Embase (1988 to June 2018), Education Resource Information Center (ERIC; EBSCOhost; 1966 to June 2018), PsycINFO (Ovid 1806 to June 2018), and Google Scholar. We also searched clinical trial registers and handsearched references of topic‐related systematic reviews and the included studies.

**Selection criteria**
We included randomised controlled trials (RCTs) and cluster RCTs (C‐RCTs) involving the parents of school‐aged children who were part of the general population with no known risk factors (universal interventions), were at elevated risk of alcohol use or problem drinking (selective interventions), or were already consuming alcohol (indicated interventions). Psychosocial or educational interventions involving parents with or without involvement of children were compared with no intervention, or with alternate (e.g. child only) interventions, allowing experimental isolation of parent components.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane.

**Main results**
We included 46 studies (39,822 participants), with 27 classified as universal, 12 as selective, and seven as indicated. We performed meta‐analyses according to outcome, including studies reporting on the prevalence, frequency, or volume of alcohol use. The overall quality of evidence was low or very low, and there was high, unexplained heterogeneity.

Upon comparing any family intervention to no intervention/standard care, we found no intervention effect on the prevalence (standardised mean difference (SMD) 0.00, 95% confidence interval (CI) ‐0.08 to 0.08; studies = 12; participants = 7490; I&sup2; = 57%; low‐quality evidence) or frequency (SMD ‐0.31, 95% CI ‐0.83 to 0.21; studies = 8; participants = 1835; I&sup2; = 96%; very low‐quality evidence) of alcohol use in comparison with no intervention/standard care. The effect of any parent/family interventions on alcohol consumption volume compared with no intervention/standard care was very small (SMD ‐0.14, 95% CI ‐0.27 to 0.00; studies = 5; participants = 1825; I&sup2; = 42%; low‐quality evidence).

When comparing parent/family and adolescent interventions versus interventions with young people alone, we found no difference in alcohol use prevalence (SMD ‐0.39, 95% CI ‐0.91 to 0.14; studies = 4; participants = 5640; I&sup2; = 99%; very low‐quality evidence) or frequency (SMD ‐0.16, 95% CI ‐0.42 to 0.09; studies = 4; participants = 915; I&sup2; = 73%; very low‐quality evidence). For this comparison, no trials reporting on the volume of alcohol use could be pooled in meta‐analysis.

In general, the results remained consistent in separate subgroup analyses of universal, selective, and indicated interventions. No adverse effects were reported.

**Authors&#039; conclusions**
The results of this review indicate that there are no clear benefits of family‐based programmes for alcohol use among young people. Patterns differ slightly across outcomes, but overall, the variation, heterogeneity, and number of analyses performed preclude any conclusions about intervention effects. Additional independent studies are required to strengthen the evidence and clarify the marginal effects observed.
AU  - Gilligan,
AU  - C.
AU  - Wolfenden,
AU  - L.
AU  - Foxcroft,
AU  - D.
AU  - R.
AU  - Williams,
AU  - A.
AU  - J.
AU  - Kingsland,
AU  - M.
AU  - Hodder,
AU  - R.
AU  - K.
AU  - Stockings,
AU  - E.
AU  - McFadyen,
AU  - T-R.
AU  - Tindall,
AU  - J.
AU  - Sherker,
AU  - S.
AU  - Rae,
AU  - J.
AU  - Wiggers,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.CD012287.pub2
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Family‐based prevention programmes for alcohol use in young people
ER  -
TY  - JOUR
AB  - **INTRODUCTION:** 
Micronutrient (MN) deficiencies cause a considerable burden of disease for children in many countries. Dairy products or cereals are an important food component during adolescence. Fortification of dairy products or cereals with MN may be an effective strategy to overcome MN deficiencies, but their specific impact on health in this age group is poorly documented.

**METHODS:** 
We performed a systematic review and meta-analysis (registration number CRD42016039554) to assess the impact of MN fortified dairy products and cereal food on the health of children and adolescents (aged 5-15 years) compared with non-fortified food. We reviewed randomised controlled trials (RCT) using electronic databases (MEDLINE, EMBASE, Cochrane library; latest search: January 2018), reference list screening and citation searches. Three pairs of reviewers assessed 2048 studies for eligibility and extracted data. We assessed the risk of bias and applied GRADE to rate quality of evidence.

**RESULTS:** 
We included 24 RCT (often multi MN fortification) with 30 pair-wise comparisons mainly from low- and middle income countries. A very small and non-significant increase of haemoglobin values emerged (0.09 g/dl [95%-CI: -0.01 to 0.18]; 13 RCT with iron fortification; very low quality of evidence). No significant difference was found on anaemia risk (risk ratio 0.87 [95%-CI: 0.76 to 1.01]; 12 RCT; very low quality), but a significant difference in iron deficiency anaemia favouring fortified food was found (risk ratio 0.38 [95%-CI: 0.18 to 0.81]; 5 RCT; very low quality). Similar effects were seen for fortified dairy products and cereals and different fortification strategies (mono- vs. dual- vs. multi-MN). Follow-up periods were often short and the impact on anthropometric measures was weak (low quality of evidence) Very low quality of evidence emerged for the improvement of cognitive performance, functional measures and morbidity.

**CONCLUSIONS:** 
Fortification of dairy products and cereal food had only marginal health effects in our sample population from 5-15 years. Further evidence is needed to better understand the health impact of fortified dairy products and cereals in this age group.SYSTEMATIC REVIEW REGISTRATION: The study protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 26 May 2016 (registration number CRD42016039554).
AD  - Eichler, Klaus. Winterthur Institute of Health Economics, Zurich University of Applied Sciences, Winterthur, Switzerland.Hess, Sascha. Winterthur Institute of Health Economics, Zurich University of Applied Sciences, Winterthur, Switzerland.Twerenbold, Claudia. Winterthur Institute of Health Economics, Zurich University of Applied Sciences, Winterthur, Switzerland.Sabatier, Magalie. Nestle Research Center, Public Health Department, Lausanne, Switzerland.Meier, Flurina. Winterthur Institute of Health Economics, Zurich University of Applied Sciences, Winterthur, Switzerland.Wieser, Simon. Winterthur Institute of Health Economics, Zurich University of Applied Sciences, Winterthur, Switzerland.
AN  - 30673769
AU  - Eichler,
AU  - K.
AU  - Hess,
AU  - S.
AU  - Twerenbold,
AU  - C.
AU  - Sabatier,
AU  - M.
AU  - Meier,
AU  - F.
AU  - Wieser,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0210899
DP  - Ovid Technologies
J2  - PLoS ONE
KW  - Adolescent
KW  - Adolescent Nutritional Physiological Phenomena
KW  - Anemia, Iron-Deficiency/ep [Epidemiology]
KW  - Body Composition
KW  - Child
KW  - Child Nutritional Physiological Phenomena
KW  - Child, Preschool
KW  - Cognition
KW  - Dairy Products/an [Analysis]
KW  - *Dairy Products
KW  - Edible Grain/ch [Chemistry]
KW  - *Edible Grain
KW  - Female
KW  - Food, Fortified/an [Analysis]
KW  - *Food, Fortified
KW  - Hemoglobins/me [Metabolism]
KW  - Humans
KW  - Male
KW  - *Micronutrients/ad [Administration &amp; Dosage]
KW  - Micronutrients/df [Deficiency]
KW  - Prevalence
KW  - Randomized Controlled Trials as Topic
KW  - 0 (Hemoglobins)
KW  - 0 (Micronutrients)
L1  - internal-pdf://0236145650/Eichler-2019-Health effects of micronutrient f.pdf
LA  - English
M3  - Meta-Analysis
Research Support, Non-U.S. Gov&#039;t
Systematic Review
N1  - Eichler, KlausHess, SaschaTwerenbold, ClaudiaSabatier, MagalieMeier, FlurinaWieser, Simon
PY  - 2019
SP  - e0210899
T2  - PLoS ONE [Electronic Resource]
TI  - Health effects of micronutrient fortified dairy products and cereal food for children and adolescents: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=30673769
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343890/pdf/pone.0210899.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - **Objective**
Although there is sufficient research and clinical evidence to support the inclusion of gaming disorder in the latest revision of the International Classification of Diseases, relatively little is known about the effectiveness of first‐line psychological treatment for gaming disorder or internet gaming disorder (IGD) as it is listed in the Diagnostic and Statistical Manual. This systematic review employed meta‐analytic techniques to determine the effectiveness of cognitive&ndash;behavioural therapy (CBT) for IGD on four key outcomes: IGD symptoms, anxiety, depression, and time spent gaming.

**Method**
A database search identified 12 independent CBT studies. Effect size estimates (Hedges&#039; g) with associated confidence intervals, prediction intervals, and p values for each pre&ndash;post treatment outcome, were calculated. Study reporting quality was evaluated in accordance with the Consolidated Standards of Reporting Trials guidelines. Subgroup and moderator analyses were undertaken to investigate potential sources of heterogeneity.

**Results**
CBT demonstrated high efficacy in reducing IGD symptoms (g = 0.92; [0.50, 1.34]) and depression (g = 0.80, [0.21, 1.38]), and showed moderate efficacy in reducing anxiety (g = 0.55, [0.17, 0.93]) at post‐test. There was insufficient power to determine whether CBT was capable of reducing time spent gaming. Treatment gains at follow‐up were nonsignificant across the four treatment outcomes.

**Conclusions**
The pooled findings suggest that CBT for IGD is an effective short‐term intervention for reducing IGD and depressive symptoms. However, the effectiveness of CBT for reducing actual time spent gaming was unclear. Given the limitations of this evidence base, there is a need for more rigorous studies to determine the potential long‐term benefits of CBT for IGD.

**Public Health Significance Statement**
Given the rise in treatment demand for internet gaming disorder (IGD) and problematic gaming, it is necessary to determine which treatments are most effective for whom and under which conditions. This review shows that cognitive‐behavioural therapy for IGD, which is often considered the first‐line therapy, can improve IGD symptoms and comorbid depression. However, treatment gains tend to be short‐term and their effect in reducing time spent gaming is unclear. Programs that target problematic gaming may be improved by additional support beyond the standard program of therapy sessions. More funding and resources are needed to support the development of a more rigorous evidence base on IGD and its treatment.
AN  - WOS:000468312200004
AU  - Stevens,
AU  - M.
AU  - W.
AU  - R.
AU  - King,
AU  - D.
AU  - L.
AU  - Dorstyn,
AU  - D.
AU  - Delfabbro,
AU  - P.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/cpp.2341
L1  - internal-pdf://1135646270/Stevens-2019-Cognitive-behavioral therapy for.pdf
PY  - 2019
SP  - 191-203
T2  - Clinical Psychology &amp; Psychotherapy
TI  - Cognitive-behavioral therapy for Internet gaming disorder: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000468312200004
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpp.2341
VL  - 26
ER  -
TY  - JOUR
AB  - Background
Multiple‐micronutrient (MMN) deficiencies often coexist among women of reproductive age in low‐ and middle‐income countries. They are exacerbated in pregnancy due to the increased demands of the developing fetus, leading to potentially adverse effects on the mother and baby. A consensus is yet to be reached regarding the replacement of iron and folic acid supplementation with MMNs. Since the last update of this Cochrane Review in 2017, evidence from several trials has become available. The findings of this review will be critical to inform policy on micronutrient supplementation in pregnancy.

Objectives
To evaluate the benefits of oral multiple‐micronutrient supplementation during pregnancy on maternal, fetal and infant health outcomes.

Search methods
For this 2018 update, on 23 February 2018 we searched Cochrane Pregnancy and Childbirth&rsquo;s Trials Register, ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform (ICTRP), and reference lists of retrieved studies. We also contacted experts in the field for additional and ongoing trials.

Selection criteria
All prospective randomised controlled trials evaluating MMN supplementation with iron and folic acid during pregnancy and its effects on pregnancy outcomes were eligible, irrespective of language or the publication status of the trials. We included cluster‐randomised trials, but excluded quasi‐randomised trials. Trial reports that were published as abstracts were eligible.

Data collection and analysis
Two review authors independently assessed trials for inclusion and risk of bias, extracted data and checked them for accuracy. We assessed the quality of the evidence using the GRADE approach.

Main results
We identified 21 trials (involving 142,496 women) as eligible for inclusion in this review, but only 20 trials (involving 141,849 women) contributed data. Of these 20 trials, 19 were conducted in low‐ and middle‐income countries and compared MMN supplements with iron and folic acid to iron, with or without folic acid. One trial conducted in the UK compared MMN supplementation with placebo. In total, eight trials were cluster‐randomised.

MMN with iron and folic acid versus iron, with or without folic acid (19 trials)
MMN supplementation probably led to a slight reduction in preterm births (average risk ratio (RR) 0.95, 95% confidence interval (CI) 0.90 to 1.01; 18 trials, 91,425 participants; moderate‐quality evidence), and babies considered small‐for‐gestational age (SGA) (average RR 0.92, 95% CI 0.88 to 0.97; 17 trials; 57,348 participants; moderate‐quality evidence), though the CI for the pooled effect for preterm births just crossed the line of no effect. MMN reduced the number of newborn infants identified as low birthweight (LBW) (average RR 0.88, 95% CI 0.85 to 0.91; 18 trials, 68,801 participants; high‐quality evidence). We did not observe any differences between groups for perinatal mortality (average RR 1.00, 95% CI 0.90 to 1.11; 15 trials, 63,922 participants; high‐quality evidence). MMN supplementation led to slightly fewer stillbirths (average RR 0.95, 95% CI 0.86 to 1.04; 17 trials, 97,927 participants; high‐quality evidence) but, again, the CI for the pooled effect just crossed the line of no effect. MMN supplementation did not have an important effect on neonatal mortality (average RR 1.00, 95% CI 0.89 to 1.12; 14 trials, 80,964 participants; high‐quality evidence). We observed little or no difference between groups for the other maternal and pregnancy outcomes: maternal anaemia in the third trimester (average RR 1.04, 95% CI 0.94 to 1.15; 9 trials, 5912 participants), maternal mortality (average RR 1.06, 95% CI 0.72 to 1.54; 6 trials, 106,275 participants), miscarriage (average RR 0.99, 95% CI 0.94 to 1.04; 12 trials, 100,565 participants), delivery via a caesarean section (average RR 1.13, 95% CI 0.99 to 1.29; 5 trials, 12,836 participants), and congenital anomalies (average RR 1.34, 95% CI 0.25 to 7.12; 2 trials, 1958 participants). However, MMN supplementation probably led to a reduction in very preterm births (average RR 0.81, 95% CI 0.71 to 0.93; 4 trials, 37,701 participants). We were unable to assess a number of prespecified, clinically important outcomes due to insufficient or non‐available data.

When we assessed primary outcomes according to GRADE criteria, the quality of evidence for the review overall was moderate to high. We graded the following outcomes as high quality: LBW, perinatal mortality, stillbirth, and neonatal mortality. The outcomes of preterm birth and SGA we graded as moderate quality; both were downgraded for funnel plot asymmetry, indicating possible publication bias.

We carried out sensitivity analyses excluding trials with high levels of sample attrition (&gt; 20%). We found that results were consistent with the main analyses for all outcomes. We explored heterogeneity through subgroup analyses by maternal height, maternal body mass index (BMI), timing of supplementation, dose of iron, and MMN supplement formulation (UNIMMAP versus non‐UNIMMAP). There was a greater reduction in preterm births for women with low BMI and among those who took non‐UNIMMAP supplements. We also observed subgroup differences for maternal BMI and maternal height for SGA, indicating greater impact among women with greater BMI and height. Though we found that MMN supplementation made little or no difference to perinatal mortality, the analysis demonstrated substantial statistical heterogeneity. We explored this heterogeneity using subgroup analysis and found differences for timing of supplementation, whereby higher impact was observed with later initiation of supplementation. For all other subgroup analyses, the findings were inconclusive.

MMN versus placebo (1 trial)
A single trial in the UK found little or no important effect of MMN supplementation on preterm births, SGA, or LBW but did find a reduction in maternal anaemia in the third trimester (RR 0.66, 95% CI 0.51 to 0.85), when compared to placebo. This trial did not measure our other outcomes.

Authors&#039; conclusions
Our findings suggest a positive impact of MMN supplementation with iron and folic acid on several birth outcomes. MMN supplementation in pregnancy led to a reduction in babies considered LBW, and probably led to a reduction in babies considered SGA. In addition, MMN probably reduced preterm births. No important benefits or harms of MMN supplementation were found for mortality outcomes (stillbirths, perinatal and neonatal mortality). These findings may provide some basis to guide the replacement of iron and folic acid supplements with MMN supplements for pregnant women residing in low‐ and middle‐income countries.
AU  - Keats,
AU  - E.
AU  - Haider,
AU  - B.
AU  - Tam,
AU  - E.
AU  - Bhutta,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004905.pub5
KW  - CD004905
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Multiple-micronutrient supplementation for women during pregnancy
ER  -
TY  - JOUR
AB  - **Background:** 
The psychological well-being of parents and children is compromised in families characterized by greater parenting stress. As parental mindfulness is associated with lower parenting stress, a growing number of studies have investigated whether mindfulness interventions can improve outcomes for families. This systematic review and meta-analysis evaluates the effectiveness of mindfulness interventions for parents, in reducing parenting stress and improving youth psychological outcomes. 

**Methods:** 
A literature search for peer-reviewed articles and dissertations was conducted in accordance with PRISMA guidelines in the PsycInfo, Medline, PubMed, CINAHL, Web of Science, Cochrane Central Register of Controlled Trials, and ProQuest Dissertations &amp; Theses databases. Studies were included if they reported on a mindfulness-based intervention delivered in person to parents with the primary aim of reducing parenting stress or improving youth psychological outcomes. 

**Results:** 
Twenty-five independent studies were included in the review. Eighteen studies used a single group design and six were randomized controlled trials. Within-groups, meta-analysis indicated a small, post-intervention reduction in parenting stress (g = 0.34), growing to a moderate reduction at 2 month follow-up (g = 0.53). Overall, there was a small improvement in youth outcomes (g = 0.27). Neither youth age or clinical status, nor time in mindfulness training, moderated parenting stress or overall youth outcome effects. Youth outcomes were not moderated by intervention group attendees. Change in parenting stress predicted change in youth externalizing and cognitive effects, but not internalizing effects. In controlled studies, parenting stress reduced more in mindfulness groups than control groups (g = 0.44). Overall, risk of bias was assessed as serious.

**Conclusions:** 
Mindfulness interventions for parents may reduce parenting stress and improve youth psychological functioning. While improvements in youth externalizing and cognitive outcomes may be explained by reductions in parenting stress, it appears that other parenting factors may contribute to improvements in youth internalizing outcomes. Methodological weaknesses in the reviewed literature prevent firm conclusions from being drawn regarding effectiveness. Future research should address these methodological issues before mindfulness interventions for parents are recommended as an effective treatment option for parents or their children.
AN  - WOS:000471281500001
AU  - Burgdorf,
AU  - V.
AU  - Szabo,
AU  - M.
AU  - Abbott,
AU  - M.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3389/fpsyg.2019.01336
L1  - internal-pdf://1322228695/Burgdorf-2019-The Effect of Mindfulness Interv.pdf
PY  - 2019
SP  - 27
T2  - Frontiers in Psychology
TI  - The Effect of Mindfulness Interventions for Parents on Parenting Stress and Youth Psychological Outcomes: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000471281500001
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/433825/pubmed-zip/.versions/1/.package-entries/fpsyg-10-01336/fpsyg-10-01336.pdf?sv=2015-12-11&amp;sr=b&amp;sig=hQYSxyoYUc5ssjM%2BKySP%2B9wWnBqXGAf5gm0WlSRnBJA%3D&amp;se=2019-07-31T07%3A58%3A33Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyg-10-01336.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - Numerous interventions to address posttraumatic stress (PTS) in youth exposed to mass trauma have been delivered and evaluated. It remains unclear, however, which interventions work for whom and under what conditions. This report describes a meta-analysis of the effect of youth mass-trauma interventions on PTS to determine if interventions were superior to inactive controls and describes a moderator analysis to examine whether the type of event, population characteristics, or income level of the country where the intervention was delivered may have affected the observed effect sizes. 

A comprehensive literature search identified randomized controlled trials (RCTs) of youth mass-trauma interventions relative to inactive controls. The search identified 2,232 references, of which 25 RCTs examining 27 trials (N = 4,662 participants) were included in this meta-analysis. 

Intervention effects were computed as Hedge&#039;s g estimates and combined using a random effects model. Moderator analyses were conducted to explain the observed heterogeneity among effect sizes using the following independent variables: disaster type (political violence versus natural disaster); sample type (targeted versus non-targeted); and income level of the country where the intervention was delivered (high- versus middle- versus low-income). The correlation between the estimates of the intervention effects on PTS and on functional impairment was estimated. The overall treatment effect size was converted into a number needed to treat (NNT) for a practical interpretation. The overall intervention effect was statistically significant (g = 0.57; P &lt; .0001), indicating that interventions had a medium beneficial effect on PTS. None of the hypothesized moderators explained the heterogeneity among the intervention effects. Estimates of the intervention effects on PTS and on functional impairment were positively correlated (Spearman&#039;s r = 0.90; P &lt; .0001), indicating a concomitant improvement in both outcomes. These findings confirm that interventions can alleviate PTS and enhance functioning in children exposed to mass trauma. This study extends prior research by demonstrating improvement in PTS with interventions delivered to targeted and non-targeted populations, regardless of the country income level. Intervention populations and available resources should be considered when interpreting the results of intervention studies to inform recommendations for practice.
AD  - Pfefferbaum, Betty. Department of Psychiatry and Behavioral Sciences, College of Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, OklahomaUSA.Nitiema, Pascal. Department of Management Information Systems, Price College of Business, The University of Oklahoma, Norman, OklahomaUSA.Newman, Elana. Department of Psychology, The University of Tulsa, Tulsa, OklahomaUSA.Patel, Anushka. Department of Psychology, The University of Tulsa, Tulsa, OklahomaUSA.
AN  - 31455447
AU  - Pefferbaum,
AU  - B.
AU  - Nitiema,
AU  - P.
AU  - Newman,
AU  - E.
AU  - Patel,
AU  - A.
DA  - Aug 28
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1017/S1049023X19004771
DP  - Ovid Technologies
J2  - Prehospital Disaster Med
L1  - internal-pdf://0286845417/Pfefferbaum-2019.pdf
LA  - English
N1  - Pfefferbaum, BettyNitiema, PascalNewman, ElanaPatel, Anushka
PY  - 2019
SP  - 1-12
T2  - Prehospital &amp; Disaster Medicine
TI  - The Benefit of Interventions to Reduce Posttraumatic Stress in Youth Exposed to Mass Trauma: A Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31455447
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31455447&amp;id=doi:10.1017%2FS1049023X19004771&amp;issn=1049-023X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-12&amp;date=2019&amp;title=Prehospital+%26+Disaster+Medicine&amp;atitle=The+Benefit+of+Interventions+to+Reduce+Posttraumatic+Stress+in+Youth+Exposed+to+Mass+Trauma%3A+A+Review+and+Meta-Analysis.&amp;aulast=Pfefferbaum&amp;pid=%3Cauthor%3EPfefferbaum+B%3C%2Fauthor%3E%3CAN%3E31455447%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.cambridge.org/core/journals/prehospital-and-disaster-medicine/article/benefit-of-interventions-to-reduce-posttraumatic-stress-in-youth-exposed-to-mass-trauma-a-review-and-metaanalysis/E5515248AC5626533E52EEAEE947D4CD
ER  -
TY  - JOUR
AB  - **Background:** 
To investigate the efficacy and safety of omega-3 fatty acids (O3FA) in treating depressive disorders in children and adolescents.

**Method:** 
We conducted a comprehensive search in electronic databases and hand-searched articles included for relevant studies. We included randomized controlled trials which studied on O3FA for treatment of children and adolescents with depression. The standard mean differences (SMDs) and the odds ratios (ORs) with 95% confidence intervals (CIs) were estimated by a random-effects model. The primary outcomes were end-point depressive symptoms scores (efficacy) and all-cause discontinuation (safety). The secondary outcome of response rate was also assessed. Subgroup analyses were performed by age, severity of depression and dosage. Risk of bias assessment was performed based on the Jadad score and the Cochrane Collaboration&#039;s risk-of-bias method.

**Results:** 
A total of four studies with 153 participants were included. In terms of efficacy, there was no significant difference of end-point depressive symptoms scores between O3FA and placebo (SMD = - 0.12, 95% CI - 0.53 to 0.30, P = 0.58; I &lt;sup&gt;2&lt;/sup&gt;= 30%). In terms of safety, the all-cause discontinuation showed no statistical significance between O3FA and placebo (OR = 1.3, 95% CI 0.58 to 2.93, P = 0.53; I &lt;sup&gt;2&lt;/sup&gt;= 0%). The response rate of O3FA was also not significant better than that of placebo (OR = 1.57, 95% CI 0.26 to 9.39, P = 0.62; I &lt;sup&gt;2&lt;/sup&gt;= 71%). Besides, there were also no significant differences in those subgroup analyses outcomes. The risk of bias of included trials were not high.

**Conclusions:** 
Only considering the limited evidence of O3FA in the acute treatment of major depressive disorder, it did not seem to offer a clear advantage for children and adolescents.
AD  - Zhang, Li. 1The First Branch, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Liu, Huan. 2Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing, 400016 People&#039;s Republic of China.Kuang, Li. 2Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing, 400016 People&#039;s Republic of China.Meng, Huaqing. 2Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing, 400016 People&#039;s Republic of China.Zhou, Xinyu. 2Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing, 400016 People&#039;s Republic of China.
AN  - 31534476
AU  - Zhang,
AU  - L.
AU  - Liu,
AU  - H.
AU  - Kuang,
AU  - L.
AU  - Meng,
AU  - H.
AU  - Zhou,
AU  - X.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1186/s13034-019-0296-x
DP  - Ovid Technologies
J2  - Child Adolesc Psychiatry Ment Health
L1  - internal-pdf://2456611946/Zhang-2019-Omega-3 fatty acids for the treatme.pdf
LA  - English
N1  - Zhang, LiLiu, HuanKuang, LiMeng, HuaqingZhou, Xinyu
PY  - 2019
SP  - 36
T2  - Child &amp; Adolescent Psychiatry &amp; Mental Health [Electronic Resource]
TI  - Omega-3 fatty acids for the treatment of depressive disorders in children and adolescents: a meta-analysis of randomized placebo-controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31534476
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31534476&amp;id=doi:10.1186%2Fs13034-019-0296-x&amp;issn=1753-2000&amp;isbn=&amp;volume=13&amp;issue=&amp;spage=36&amp;pages=36&amp;date=2019&amp;title=Child+%26+Adolescent+Psychiatry+%26+Mental+Health+%5BElectronic+Resource%5D&amp;atitle=Omega-3+fatty+acids+for+the+treatment+of+depressive+disorders+in+children+and+adolescents%3A+a+meta-analysis+of+randomized+placebo-controlled+trials.&amp;aulast=Zhang&amp;pid=%3Cauthor%3EZhang+L%3C%2Fauthor%3E%3CAN%3E31534476%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://capmh.biomedcentral.com/track/pdf/10.1186/s13034-019-0296-x
VL  - 13
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** 
The objective of this systematic review was to identify, evaluate and synthesize evidence of the effectiveness of vibratory stimulation to reduce needle-related procedural pain in children aged 18 years and younger. 

**INTRODUCTION:** 
Needle-related procedures (NRPs) are common medical procedures associated with pain. Children, in particular, experience unpredictable and severe pain in response to NRPs. The gate control theory is commonly used to countermeasure this pain. Based on this theory, various types of vibratory stimulation have been used to reduce pain in several clinical studies.

**INCLUSION CRITERIA:** 
Participants were 0- to 18-year-old children who underwent NRPs for any condition. The intervention included any type of vibratory stimulation during the NRPs. The main outcome was pain measured on any pain scale, including both self-rated and observer-rated pain scales. The secondary outcomes were anxiety, the duration of the procedure and the success rate. All studies were randomized controlled trials (RCTs) or quasi-randomized trials published in English. 

**METHODS:** 
The search strategy aimed to identify both published and unpublished studies. A three-step search strategy was utilized in this review. An initial search of MEDLINE and CINAHL was undertaken, followed by a search for unpublished studies. Nine databases were used for the search in October 2017. Papers selected for retrieval were assessed by two independent reviewers for methodological validity prior to inclusion in the review using standardized critical appraisal instruments. Any disagreements that arose between the reviewers were resolved through discussion. Quantitative data were extracted from papers included in the review using a standardized data extraction tool. Where possible, quantitative data were pooled in the statistical meta-analysis. All results were subject to double data entry. Effect sizes were expressed as risk ratios (for categorical data) and weighted mean differences (for continuous data), and their 95% confidence intervals were calculated for analysis. 

**RESULTS:** 
Twenty-one RCTs involving 1727 children were identified. Blinding of the participants and those delivering the treatment was not achieved in all studies, introducing a potential risk of bias. Overall, the vibratory stimulation was significantly effective in reducing NRP pain in children as shown by measurement of self-rated pain outcomes (standardized mean difference [SMD]: -0.55, 95% confidence interval [CI]: -0.92 to -0.18) and observer-rated pain outcomes (SMD: -0.47, 95% CI: -0.76 to -0.18). Among secondary outcomes, the effect on the child&#039;s anxiety (SMD: -1.03, 95% CI: -1.85 to -0.20) was significant. 

**CONCLUSIONS:** 
Vibratory stimulation was effective in reducing NRP pain in children; however, blinding was not possible in the trials. Moreover, heterogeneity was high. Therefore, the confidence in the evidence is low. Personal preference should be a priority when using vibratory stimulation in the clinical setting.
AN  - 31021972
AU  - Ueki,
AU  - S.
AU  - Yamagami,
AU  - Y.
AU  - Makimoto,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.11124/JBISRIR-2017-003890
L1  - internal-pdf://1485631183/Ueki-2019.pdf
PY  - 2019
SP  - 1428-1463
T2  - JBI Database of Systematic Reviews and Implementation Reports
TI  - Effectiveness of vibratory stimulation on needle-related procedural pain in children: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31021972
VL  - 17
ER  -
TY  - JOUR
AB  - Naturalistic developmental behavioral intervention is an emerging class of interventions for young children with autism spectrum disorder. The present article is a meta-analysis of outcomes of group-design studies ( n = 27) testing interventions using naturalistic developmental behavioral intervention strategies. 

Small, significant positive effects of naturalistic developmental behavioral intervention were found for expressive language ( g = 0.32), reduction in symptoms of autism spectrum disorder ( g = -0.38), and play skills ( g = 0.23). Larger effects were found for social engagement ( g = 0.65) and overall cognitive development ( g = 0.48). 

A marginal effect was found for joint attention ( g = 0.14) and receptive language ( g = 0.28). For joint attention, improvement was moderated by hours of professional involvement. Evidence of publication and reporting bias was present for language outcomes. 

This meta-analysis grows the evidence base for naturalistic developmental behavioral interventions, particularly in the key areas of social engagement and cognition.
AN  - 31018655
AU  - Tiede,
AU  - G.
AU  - Walton,
AU  - K.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1362361319836371
L1  - internal-pdf://3867145547/Tiede-2019-Meta-analysis of naturalistic devel.pdf
PY  - 2019
SP  - 1362361319836371
T2  - Autism
TI  - Meta-analysis of naturalistic developmental behavioral interventions for young children with autism spectrum disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31018655
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
Conduct disorder (CD) is a common mental health disorder of childhood and adolescence. CD&#039;s complexity, with its heterogenous clinical manifestations and overlapping comorbidities makes the application of evidence-based management approaches challenging. This article aims to combine a systematic review of the available literature, with a consensus opinion from both child and adolescent psychiatrists and developmental pediatricians on the clinical and pharmacological management of children and adolescents with conduct disorder (CD). 

**Areas covered: **
The authors review the CD population and provide a systematic review and meta-analysis of the effectiveness and safety of pharmacotherapies using preferred reporting items for systematic review and meta-analysis (PRISMA) and strength of evidence recommendation taxonomy (SORT) guidelines. The authors then provide an expert clinical opinion for the use of different pharmacotherapies to address aggressive and disruptive behavior in children. 

**Expert opinion: **
Atypical antipsychotics (e.g. risperidone) demonstrate evidence for efficacy in CD. Other pharmacotherapies (e.g. mood stabilizers, anticonvulsants, psychostimulants and selective norepinephrine reuptake inhibitors) have a low level of evidence for CD alone, however, can sometimes be effective in managing the symptoms of CD when other psychiatric disorders are also present.
AN  - 30702354
AU  - Khan,
AU  - S.
AU  - Down,
AU  - J.
AU  - Aouira,
AU  - N.
AU  - Bor,
AU  - W.
AU  - Haywood,
AU  - A.
AU  - Littlewood,
AU  - R.
AU  - Heussler,
AU  - H.
AU  - McDermott,
AU  - B.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/14656566.2018.1561862
L1  - internal-pdf://2854493011/Khan-2019-Current pharmacotherapy options for.pdf
PY  - 2019
SP  - 1-13
T2  - Expert Opinion on Pharmacotherapy
TI  - Current pharmacotherapy options for conduct disorders in adolescents and children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30702354
UR  - https://www.tandfonline.com/doi/full/10.1080/14656566.2018.1561862
ER  -
TY  - JOUR
AB  - **Background** 
Interpersonal psychotherapy for adolescents (IPT-A) is a manualised, time-limited intervention for young people with depression. This systematic review aimed to determine the effectiveness of IPT-A for treating adolescent depression. 

**Method** 
A systematic search of relevant electronic databases and study reference lists was conducted. Any study investigating the effectiveness of IPT-A in 12- to 20-year-olds with a depressive disorder was eligible. Synthesis was via narrative summary and meta-analysis. 

**Results** 
Twenty studies were identified (10 randomised trials and 10 open trials/case studies), many of which had small sample sizes and were of varying quality. Following IPT-A, participants experienced large improvements in depression symptoms (d = -1.48, p &lt; .0001, k = 17), interpersonal difficulties with a medium effect (d = -0.68, p &lt; .001, k = 8) and in general functioning with a very large effect (d = 2.85, p &lt; .001, k = 8). When compared against control interventions, IPT-A was more effective than non-CBT active controls in reducing depression symptoms (d = -0.64, p &lt; .001, k = 5) and was no different from CBT (d = 0.05, p = .88, k = 2). There was no difference between IPT-A and active control interventions in reducing interpersonal difficulties (d = -0.26, p = .25, k = 5). 

**Conclusions** 
Interpersonal psychotherapy for adolescents is an effective intervention for adolescent depression, improving a range of relevant outcomes. IPT-A is consistently superior to less structured interventions and performs similarly to CBT. However, these conclusions are cautious, as they are based on a small number of controlled studies, with minor adaptations to the standard IPT-A protocol, and/or were conducted by the intervention developers. Further robust RCTs are therefore required. The lack of superiority in IPT-A for improving interpersonal difficulties highlights a need for studies to explore the underpinning mechanisms of change.
AD  - [Duffy, Fiona; Sharpe, Helen; Schwannauer, Matthias] Univ Edinburgh, Sch Hlth Social Sci, Dept Clin Psychol, Old Med Bldg,Teviot Pl, Edinburgh EH8 9AG, Midlothian, Scotland.Duffy, F (reprint author), Univ Edinburgh, Sch Hlth Social Sci, Dept Clin Psychol, Old Med Bldg,Teviot Pl, Edinburgh EH8 9AG, Midlothian, Scotland.fiona.duffy@ed.ac.uk
AN  - WOS:000478270600001
AU  - Duffy,
AU  - F.
AU  - Sharpe,
AU  - H.
AU  - Schwannauer,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/camh.12342
J2  - Child Adolesc. Ment. Health
KW  - Interpersonal psychotherapy
KW  - depression
KW  - meta-analysis
KW  - adolescent
KW  - effectiveness
KW  - ipt-a
KW  - major depression
KW  - randomized-trial
KW  - northern uganda
KW  - efficacy
KW  - preadolescents
KW  - acceptability
KW  - innovations
KW  - symptoms
KW  - patterns
KW  - Psychology
KW  - Pediatrics
KW  - Psychiatry
L1  - internal-pdf://3771875304/Duffy_et_al-2019-Child_and_Adolescent_Mental_H.pdf
LA  - English
M3  - Review; Early Access
N1  - ISI Document Delivery No.: IM8XKTimes Cited: 0Cited Reference Count: 63Duffy, Fiona Sharpe, Helen Schwannauer, MatthiasDuffy, Fiona/0000-0002-9162-97220WileyHoboken1475-3588
PY  - 2019
SP  - 11
T2  - Child and Adolescent Mental Health
TI  - Review: The effectiveness of interpersonal psychotherapy for adolescents with depression - a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000478270600001
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1111/camh.12342
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/camh.12342
ER  -
TY  - JOUR
AB  - **Background: **
Harms related to gambling have been found not only to affect problem gamblers, but also to occur amongst low- and moderate-risk gamblers. This has resulted in calls for a public health approach to address a possible &#039;prevention paradox&#039; in gambling related harm. The aim of this study was to evaluate the systematic review evidence base on the effects of prevention and harm reduction interventions on gambling behaviours, and gambling related harm. We also aimed to examine differential effects of interventions across socio-demographic groups. 

**Methods: **
Systematic methods were used to locate and evaluate published systematic reviews of prevention and harm reduction interventions. We designed the review using the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) Equity extension Guidelines. Four databases were searched from their start date until May 2018. The quality of the included articles was determined using A MeaSurement Tool to Assess systematic Reviews (AMSTAR 2). 

**Results: **
Ten systematic reviews were identified reporting 55 unique relevant primary studies. Much of the review evidence-base related to pre-commitment and limit setting (24%), self-exclusion (20%), youth prevention programmes (20%), and machine messages/feedback (20%). The effectiveness of harm reduction interventions are limited by the extent to which users adhere to voluntary systems. Less than half of studies examining youth prevention programmes demonstrated positive effects on behaviour. No review extracted data or reported on the differential effects of intervention strategies across sociodemographic groups. The quality of the included reviews (and their primary studies) were generally poor and clear gaps in the evidence base have been highlighted. 

**Conclusions: **
The evidence base is dominated by evaluations of individual-level harm reduction interventions, with a paucity of research on supply reduction interventions. Review conclusions are limited by the quality and robustness of the primary research. Future research should consider the equity effects of intervention strategies. 

(PsycINFO Database Record (c) 2019 APA, all rights reserved)
AN  - 2019-01533-059
AU  - McMahon,
AU  - N.
AU  - Thomson,
AU  - K.
AU  - Kaner,
AU  - E.
AU  - Bambra,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.addbeh.2018.11.048
L1  - internal-pdf://0362803008/McMahon-2019-Effects of prevention and harm re.pdf
PY  - 2019
SP  - 380-388
T2  - Addictive Behaviors
TI  - Effects of prevention and harm reduction interventions on gambling behaviours and gambling related harm: An umbrella review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2019-01533-059
UR  - https://www.sciencedirect.com/science/article/pii/S0306460318311444?via%3Dihub
VL  - 90
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Sleep disturbances are a feature of attention-deficit/hyperactivity disorder (ADHD) and an adverse event (AE) of methylphenidate treatment. The authors sought to clarify methylphenidate-associated sleep problems and how studies are affected by confounding factors.

**DATA SOURCES: **
Published studies in English collected via online databases and unpublished data from www.clinicaltrials.gov and US Food and Drug Administration websites. Sources were searched from inception to August 2017. 

**STUDY SELECTION:**
Included were blinded placebo-controlled studies of youth with ADHD conducted in naturalistic settings, leading to 35 studies yielding 75 observations of sleep-related AEs. These studies comprised 3,079 drug-exposed and 2,606 placebo-treated patients. 

**DATA EXTRACTION: **
Two PhD-level reviewers reviewed each study for inclusion. Four PhD/PharmD-level reviewers extracted data in duplicate. Discrepancies were resolved by discussion or, if needed, by the senior author. 

**RESULTS: **
Increased pooled relative risks (RRs) were found for methylphenidate-associated sleep-related AEs for insomnia (general), initial insomnia, middle insomnia, combined insomnia, and sleep disorder. Several sample or study design features were significantly associated with the RR for sleep-related AEs and the methylphenidate formulation studied (P &lt; .05). After correction for confounding variables, significant differences among drugs were found for initial insomnia, insomnia (general), and sleep disorder (P &lt; .0001) as the other categories could not be tested due to insufficient studies. The findings also show that the RR and its interpretation are constrained by the placebo AE rate. 

**CONCLUSIONS: **
Several types of insomnia and sleep problems are associated with methylphenidate treatment. Study design and sample features influence the RR statistic. By showing that the rate of placebo AEs impacts the RR, this study provides the field with a useful covariate for adjusting RR statistics.
AN  - 31090281
AU  - Faraone,
AU  - S.
AU  - V.
AU  - Po,
AU  - M.
AU  - D.
AU  - Komolova,
AU  - M.
AU  - Cortese,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4088/JCP.18r12210
L1  - internal-pdf://1522831692/Faraone-2019-Sleep-Associated Adverse Events D.pdf
PY  - 2019
SP  - 30
T2  - Journal of Clinical Psychiatry
TI  - Sleep-Associated Adverse Events During Methylphenidate Treatment of Attention-Deficit/Hyperactivity Disorder: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31090281
UR  - http://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2019/v80/18r12210.aspx&amp;Type=Article
VL  - 80
ER  -
TY  - JOUR
AB  - **Background:** 
It has been suggested that mother-infant psychotherapy may offer an alternative approach to treating postpartum depression, but little is known about its effectiveness. This review presents a summarized effectiveness of mother-infant psychotherapy on postpartum depression. 

**Method(s):** 
Multiple electronic databases were searched including Pubmed, Cochrane Library, EMBase, MEDLINE, et al. Hand searching of references was also performed. Randomized controlled trials reporting on mother-infant psychotherapy targeting postpartum depression were included if they used a validated measure of prescribing appropriateness. Evidence quality was assessed using the Cochrane risk of bias tool. 

**Result(s):** 
A total of 13 randomized controlled trials met inclusion criteria and were included in the final analysis. In the short-term effect analysis, mother-infant psychotherapy reduced standardized mean depressive scores (-0.25, 95% CI -0.40, -0.09) and risk ratio (0.71, 95% CI 0.55, 0.91). In the long-term effect analysis, mother-infant psychotherapy did not improve maternal mood, mother-infant interaction and infant attachment. 

**Limitation(s):** 
Clinical heterogeneity was observed among included studies in mother-infant psychotherapy intervention, suggesting the existence of potential moderators such as intensity, frequency, trimester of pregnancy or type of mother-infant psychotherapy. Conclusion(s): Mother-infant psychotherapy appears to be effective for the treatment of maternal depression in the short-term. Future studies with better design/execution and larger sample size are needed to confirm the effect of mother-infant psychotherapy on short-term and to explore its effect on long-term depression. Copyright &copy; 2019 Elsevier B.V.
AD  - (Huang, Yang, Lei) Xiang Ya Nursing School of Central South University, 138 Tongzipo Road, Yuelu District, ChangshaProvince, Hunan 410013, China (Huang, Tian) School of Nursing, Hunan University of Medicine, Huaihua, Hunan, China (Yan, Lei) Department of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, 138 Tongzipo Road, Yuelu District, Changsha, Hunan Province 410013, China (Huang) Department of Preventive Medicine, School of Medicine, Hunan Normal University, Changsha, Hunan, ChinaX. Huang, Department of Preventive Medicine, School of Medicine, Hunan Normal University, Changsha, Hunan, China
AN  - 2002941480
AU  - Huang,
AU  - R.
AU  - Yang,
AU  - D.
AU  - Lei,
AU  - B.
AU  - Yan,
AU  - C.
AU  - Tian,
AU  - Y.
AU  - Huang,
AU  - X.
AU  - Lei,
AU  - J.
DA  - 1 January
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jad.2019.09.056
DP  - Ovid Technologies
KW  - Depression
KW  - Meta-analysis
KW  - Mother-infant psychotherapy
KW  - Postpartum
KW  - Systematic review
KW  - Cochrane Library
KW  - Embase
KW  - female
KW  - human
KW  - infant
KW  - long term depression
KW  - Medline
KW  - mood
KW  - postnatal depression
KW  - pregnancy
KW  - prescription
KW  - psychotherapy
KW  - randomized controlled trial (topic)
KW  - review
KW  - risk assessment
KW  - sample size
L1  - internal-pdf://2553538706/Huang-2020-The short- and long-term effectiven.pdf
LA  - English
M3  - Review
PY  - 2019
SP  - 670-679
T2  - Journal of Affective Disorders
TI  - The short- and long-term effectiveness of mother-infant psychotherapy on postpartum depression: A systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/jad
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexc&amp;AN=2002941480
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VL  - 260
ER  -
TY  - JOUR
AB  - This is the first meta-analytic review investigating what components and techniques of parent training programs for preventing or reducing child maltreatment are associated with program effectiveness. A literature search yielded 51 studies (N = 6670) examining the effectiveness of parent training programs for preventing or reducing child maltreatment. From these studies, 185 effect sizes were extracted and more than 40 program components and techniques were coded. A significant and small overall effect size was found (d = 0.416, 95% CI (0.334, 0.498), p &lt; 0.001). No significant moderating effects were found for contextual factors and structural elements (i.e., program duration, delivery location, and delivery setting). Further, no significant moderating effects were found for most of the coded program components and techniques, indicating that these components are about equally effective. Only a few program components and techniques moderated program effectiveness, however these effects were negative. These results indicated that improving parental personal skills, improving problem solving skills, and stimulating children&#039;s prosocial behavior should not be the main focus of parental training programs for preventing and reducing child maltreatment. This also holds for practicing new skills by rehearsal and giving direct feedback in program sessions. Further clinical implications and directions for future research are discussed.
AN  - 31284575
AU  - Gubbels,
AU  - J.
AU  - van
AU  - der
AU  - Put,
AU  - C.
AU  - E.
AU  - Assink,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3390/ijerph16132404
L1  - internal-pdf://2211964874/Gubbels-2019-The Effectiveness of Parent Train.pdf
PY  - 2019
SP  - 06
T2  - International Journal of Environmental Research &amp; Public Health [Electronic Resource]
TI  - The Effectiveness of Parent Training Programs for Child Maltreatment and Their Components: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31284575
UR  - https://res.mdpi.com/ijerph/ijerph-14-00156/article_deploy/ijerph-14-00156.pdf?filename=&amp;attachment=1
VL  - 16
ER  -
TY  - JOUR
AB  - With online education and programs becoming increasingly common, it is necessary to examine their effectiveness. In this study, we conduct a meta-analysis of online parenting programs. In this meta-analysis, we included 28 studies yielding 127 effect sizes examining 15 outcome variables. We found that online parenting programs had the strongest effects on increasing positive parenting and parents&#039; encouragement. We also found significant effects of reducing negative parent-child interactions, child problem behaviors, negative discipline strategies, parenting conflicts, parent stress, child anxiety, parent anger, and parent depression. Results also revealed programs&#039; significant effects on increasing parent confidence, positive child behavior and parenting satisfaction. Comparisons of programs that included clinical support (meaning programs through which participants had access to content experts, therapists, or content specialists in conjunction with the online program) versus programs that only contained online components, revealed no significant differences in 6 program outcomes between programs with and without clinical support. Comparisons of programs provided to targeted populations versus general populations revealed no significant differences in four program outcomes between populations. Results suggest that online parenting programs can provide benefits for parents who may not be able to access in-person resources. (PsycINFO Database Record (c) 2019 APA, all rights reserved)
AD  - Spencer, Chelsea M.: cspencer@ksu.eduSpencer, Chelsea M.: Department of Family Studies and Human Services, Kansas State University, 243 Campus Creek Complex, Manhattan, KS, US, 66506, cspencer@ksu.eduSpencer, Chelsea M.: Department of Family Studies and Human Services, Kansas State University, Manhattan, KS, USTopham, Glade L.: Department of Family Studies and Human Services, Kansas State University, Manhattan, KS, USKing, Erika L.: United States Air Force, San Antonio, TX, US
AN  - 2019-66479-001
AU  - Spencer,
AU  - Chelsea
AU  - M.
AU  - Topham,
AU  - Glade
AU  - L.
AU  - King,
AU  - Erika
AU  - L.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/fam0000605
DP  - Ovid Technologies
KW  - online, meta-analysis, parenting programs
KW  - *Encouragement
KW  - *Parent Child Relations
KW  - *Program Evaluation
KW  - *Parenting
KW  - Behavior Problems
KW  - Distance Education
KW  - Family Conflict
KW  - Stress
KW  - Childrearing &amp; Child Care [2956]
KW  - Human
L1  - internal-pdf://3715127023/2019-66479-001.pdf
LA  - English
M3  - Meta Analysis
PY  - 2019
SP  - No Pagination Specified
T2  - Journal of Family Psychology
TI  - Do online parenting programs create change?: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2019-66479-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2Ffam0000605&amp;issn=0893-3200&amp;isbn=&amp;volume=&amp;issue=&amp;spage=No&amp;pages=No+Pagination+Specified&amp;date=2019&amp;title=Journal+of+Family+Psychology&amp;atitle=Do+online+parenting+programs+create+change%3F%3A+A+meta-analysis.&amp;aulast=Spencer&amp;pid=%3Cauthor%3ESpencer%2C+Chelsea+M%3C%2Fauthor%3E%3CAN%3E2019-66479-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - This systematic review is aimed at examining the effectiveness of the rapid prompting method (RPM) for enhancing motor, speech, language, and communication and for decreasing problem behaviors in individuals with autism spectrum disorder (ASD). A multi-faceted search strategy was carried out. A range of participant and study variables and risk and bias indicators were identified for data extraction. RPM had to be evaluated as an intervention using a research design capable of empirical demonstration of RPM&#039;s effects. No studies met the inclusion criteria, resulting in an empty review that documents a meaningful knowledge gap. Controlled trials of RPM are warranted. Given the striking similarities between RPM and Facilitated Communication, research that examines the authorship of RPM-produced messages needs to be conducted.
AD  - [Schlosser, Ralf W.] Northeastern Univ, Dept Commun Sci &amp; Disorders, 360 Huntington Ave, Boston, MA 02115 USA. [Schlosser, Ralf W.; Shane, Howard] Boston Childrens Hosp, Ctr Commun Enhancement, Dept Otolaryngol &amp; Commun Enhancement, 9 Hope Ave, Waltham, MA 02453 USA. [Schlosser, Ralf W.] Univ Pretoria, Fac Humanities, Ctr Augmentat &amp; Alternat Commun, Pretoria, South Africa. [Hemsley, Bronwyn] Univ Technol Sydney, Grad Sch Hlth, Speech Pathol, POB 123, Ultimo, NSW 2007, Australia. [Shane, Howard] Harvard Med Sch, Otolaryngol, Boston, MA 02115 USA. [Todd, James] Eastern Michigan Univ, Dept Psychol, Ypsilanti, MI 48197 USA. [Lang, Russell] Texas State Univ, Dept Curriculum &amp; Instruct, Special Educ, 601 Univ Dr, San Marcos, TX 78666 USA. [Lilienfeld, Scott O.] Emory Univ, Dept Psychol, Room 473,Eagle Row, Atlanta, GA 30322 USA. [Lilienfeld, Scott O.] Univ Melbourne, Sch Psychol Sci, Melbourne, Vic, Australia. [Trembath, David] Griffith Univ, Sch Allied Hlth Sci, Menzies Allied Hlth Inst, 2-71 G40 Gold Coast Campus,Parklands Dr, Southport, Qld 4215, Australia. [Mostert, Mark] Regent Univ, Sch Educ, 1000 Univ Dr, Virginia Beach, VA 23454 USA. [Fong, Seraphina] Northeastern Univ, Dept Psychol, 360 Huntington Ave, Boston, MA 02115 USA. [Odom, Samuel] Univ N Carolina, Frank Porter Graham Child Dev Inst, CB 8040, Chapel Hill, NC 27599 USA.Schlosser, RW (reprint author), Northeastern Univ, Dept Commun Sci &amp; Disorders, 360 Huntington Ave, Boston, MA 02115 USA.; Schlosser, RW (reprint author), Boston Childrens Hosp, Ctr Commun Enhancement, Dept Otolaryngol &amp; Commun Enhancement, 9 Hope Ave, Waltham, MA 02453 USA.; Schlosser, RW (reprint author), Univ Pretoria, Fac Humanities, Ctr Augmentat &amp; Alternat Commun, Pretoria, South Africa.R.Schlosser@northeastern.edu
AN  - WOS:000500785100005
AU  - Schlosser,
AU  - R.
AU  - W.
AU  - Hemsley,
AU  - B.
AU  - Shane,
AU  - H.
AU  - Todd,
AU  - J.
AU  - Lang,
AU  - R.
AU  - Lilienfeld,
AU  - S.
AU  - O.
AU  - Trembath,
AU  - D.
AU  - Mostert,
AU  - M.
AU  - Fong,
AU  - S.
AU  - Odom,
AU  - S.
DA  - Dec
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1007/s40489-019-00175-w
J2  - Rev. J. Autism Dev. Disord.
KW  - Autism spectrum disorder
KW  - Facilitated communication
KW  - Rapid prompting
KW  - method
KW  - Systematic review
KW  - alternative communication intervention
KW  - speech-generating devices
KW  - single-subject research
KW  - facilitated communication
KW  - developmental-disabilities
KW  - individuals
KW  - children
KW  - science
KW  - pseudoscience
KW  - metaanalysis
KW  - Psychology
L1  - internal-pdf://0662154592/Schlosser-2019-Rapid Prompting Method and Auti.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: JT1VITimes Cited: 0Cited Reference Count: 79Schlosser, Ralf W. Hemsley, Bronwyn Shane, Howard Todd, James Lang, Russell Lilienfeld, Scott O. Trembath, David Mostert, Mark Fong, Seraphina Odom, SamuelTrembath, David/0000-0002-4699-6195; Schlosser, Ralf/0000-0002-2069-39110Springer heidelbergHeidelberg2195-7185
PY  - 2019
SP  - 403-412
T2  - Review Journal of Autism and Developmental Disorders
TI  - Rapid Prompting Method and Autism Spectrum Disorder: Systematic Review Exposes Lack of Evidence
UR  - &lt;Go to ISI&gt;://WOS:000500785100005
UR  - https://link.springer.com/content/pdf/10.1007/s40489-019-00175-w.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **Background:** 
Nutritional supplements may improve development of infants born small (preterm or small for gestational age [SGA]) but may increase the risk of later metabolic disease. We conducted a systematic review and meta-analysis to assess the effects of macronutrient supplements for infants born small on later development and metabolism. 

**Methods and findings:** 
We searched OvidMedline, Embase, Cochrane CENTRAL, and Cochrane Database of Systematic Reviews from inception to April 1, 2019, and controlled-trials.com, clinicaltrials.gov, and anzctr.org.au. Randomised or quasirandomised trials were included if the intention was to increase macronutrient intake to improve growth or development of infants born small and assessed post-discharge outcomes. Co-primary outcomes were cognitive impairment and metabolic risk, evaluated in toddlers (&lt;3 years), childhood (3 to 8 years), and adolescence (9 to 18 years). Two reviewers independently extracted data. Quality was assessed using the Cochrane Risk of Bias tool, and data were pooled using random-effect models. Twenty-one randomised and one quasirandomised trial of variable methodological quality involving 3,680 infants were included. In toddlers born small, supplementation did not alter cognitive impairment (relative risk [RR] 1.00; 95% confidence interval [CI] 0.67 to 1.49; P = 0.99), and there were no differences in cognitive scores (mean difference [MD] 0.57; 95% CI -0.71 to 1.84; P = 0.38) or motor scores (MD 1.16; 95% CI -0.32 to 2.65; P = 0.12) between supplemented and unsupplemented groups. However, fewer supplemented children had motor impairment (RR 0.76; 95% CI 0.62 to 0.94; P = 0.01). In subgroup analyses, supplementation improved cognitive scores in boys (MD 5.60; 95% CI 1.07 to 10.14; P = 0.02), but not girls born small (MD -2.04; 95% CI -7.04 to 2.95; P = 0.42), and did not alter cognitive or motor scores in the subgroup of children born SGA. In childhood, there was no difference in cognitive impairment (RR 0.81; 95% CI 0.26 to 2.57; P = 0.72) or cognitive scores (MD 1.02; 95% CI -1.91 to 3.95; P = 0.50) between supplemented and unsupplemented groups. There were also no differences in blood pressure, triglyceride, and low-density lipoprotein (LDL) concentrations (all P &gt; 0.05). However, supplemented children had lower fasting glucose (mmol/L: MD -0.20; 95% CI -0.34 to -0.06; P = 0.005) and higher high-density lipoprotein (HDL) concentrations (mmol/L: MD 0.11; 95% CI 0.02 to 0.19; P = 0.02). In subgroup analyses, there was no evidence of differences in blood pressure between supplemented and unsupplemented groups in boys or girls born small, or in SGA children. In adolescence, there was no difference between supplemented and unsupplemented groups in blood pressure, triglycerides, LDL and HDL concentrations, fasting blood glucose, insulin resistance, and fasting insulin concentrations (all P &gt; 0.05). Limitations include considerable unexplained heterogeneity, low to very low quality of the evidence, and limited data beyond early childhood. 

**Conclusion(s):** 
In this systematic review and meta-analysis of randomised trials, we found no evidence that early macronutrient supplementation for infants born small altered later cognitive function, although there was some evidence that supplementation may decrease motor impairment in toddlers. Contrary to the findings from observational studies, evidence from randomised trials suggests that early macronutrient supplementation for infants born small improves some metabolic outcomes in childhood. Copyright &copy; 2019 Lin et al.
AD  - (Lin, Amissah, Gamble, Crowther, Harding) Liggins Institute, University of Auckland, Auckland, New ZealandJ.E. Harding, Liggins Institute, University of Auckland, Auckland, New Zealand. E-mail: j.harding@auckland.ac.nz
AN  - 2003754211
AU  - Lin,
AU  - L.
AU  - Amissah,
AU  - E.
AU  - Gamble,
AU  - G.
AU  - D.
AU  - Crowther,
AU  - C.
AU  - A.
AU  - Harding,
AU  - J.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pmed.1002952
DP  - Ovid Technologies
KW  - adolescence
KW  - blood pressure
KW  - child
KW  - childhood
KW  - clinical assessment
KW  - Cochrane Library
KW  - cognitive defect
KW  - controlled study
KW  - Embase
KW  - fasting
KW  - female
KW  - glucose blood level
KW  - human
KW  - infant
KW  - insulin resistance
KW  - macronutrient
KW  - male
KW  - meta analysis
KW  - metabolic disorder
KW  - motor dysfunction
KW  - observational study
KW  - randomized controlled trial (topic)
KW  - review
KW  - risk assessment
KW  - risk factor
KW  - small for date infant
KW  - systematic review
KW  - toddler
KW  - endogenous compound
KW  - high density lipoprotein
KW  - insulin
KW  - low density lipoprotein
KW  - triacylglycerol
L1  - internal-pdf://1517834077/Lin-2019-Impact of macronutrient supplements f.pdf
LA  - English
M3  - Review
PY  - 2019
T2  - PLoS Medicine
TI  - Impact of macronutrient supplements for children born preterm or small for gestational age on developmental and metabolic outcomes: A systematic review and metaanalysis
UR  - https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1002952&amp;type=printable
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2003754211
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:31665140&amp;id=doi:10.1371%2Fjournal.pmed.1002952&amp;issn=1549-1277&amp;isbn=&amp;volume=16&amp;issue=10&amp;spage=e1002952&amp;pages=&amp;date=2019&amp;title=PLoS+Medicine&amp;atitle=Impact+of+macronutrient+supplements+for+children+born+preterm+or+small+for+gestational+age+on+developmental+and+metabolic+outcomes%3A+A+systematic+review+and+metaanalysis&amp;aulast=Lin&amp;pid=%3Cauthor%3ELin+L.%3C%2Fauthor%3E%3CAN%3E2003754211%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 16 (10) (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Audiovisual distraction, a non-pharmacological intervention, has been used to manage dental anxiety in prior clinical trials. 

**AIM: **
Synthesize the available evidences to evaluate the efficacy of audiovisual distraction techniques on the management of dental anxiety in children. 

**DESIGN: **
Electronic databases (PubMed, Cochrane Central Register of Controlled Trials, and Embase) were searched. We included randomized controlled trials (RCTs), and methodological quality of included trials was assessed using the Cochrane Collaboration&#039;s criteria. Information on reported anxiety, pain, behaviors, vital signs (including blood pressure, oxygen saturation, and pulse rate), and children satisfaction was analyzed. 

**RESULTS: **
Nine studies were included for a systematic review, and none of them had low risk of bias. Significant differences in anxiety were found. According to the study, a majority of results indicated a significant difference in pain and behavior between the audiovisual and control group. Three studies reported children in the audiovisual group preferred usage of an audiovisual device for future dental visits. No significant differences could be found regarding blood pressure. 

**CONCLUSIONS: **
There is some low-quality evidence suggesting that the usage of audiovisual distraction during dental treatment may relieve children&#039;s dental anxiety.
AN  - 30362187
AU  - Liu,
AU  - Y.
AU  - Gu,
AU  - Z.
AU  - Wang,
AU  - Y.
AU  - Wu,
AU  - Q.
AU  - Chen,
AU  - V.
AU  - Xu,
AU  - X.
AU  - Zhou,
AU  - X.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/ipd.12430
L1  - internal-pdf://4132635839/Liu-2019-Effect of audiovisual distraction on.pdf
PY  - 2019
SP  - 14-21
T2  - International Journal of Paediatric Dentistry
TI  - Effect of audiovisual distraction on the management of dental anxiety in children: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30362187
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/ipd.12430
VL  - 29
ER  -
TY  - JOUR
AB  - Mindfulness-based therapies are rising in popularity. However, evidence for their effectiveness in reducing psychological distress and enhancing wellbeing for families living with autism spectrum disorder (ASD) is limited. A systematic search identified 10 independent studies, involving a pooled sample of 233 children and adults with ASD and 241 caregivers. Hedges&#039; g effect sizes with associated 95% confidence intervals, in addition to heterogeneity, were calculated using a random-effects model. Caregivers, children and adults who received mindfulness all reported significant gains in subjective wellbeing immediately post-intervention. Available data indicated intervention effects were maintained at 3-month follow-up. Mindfulness presents a promising intervention strategy in ASD populations, however more controlled research is required to determine its precise efficacy for affected families and subgroups.
AD  - Hartley, Matthew. The School of Psychology, Faculty of Medical and Health Sciences, The University of Adelaide, North Terrace Campus, Adelaide, SA, 5005, Australia. matthew.hartley@adelaide.edu.au.Dorstyn, Diana. The School of Psychology, Faculty of Medical and Health Sciences, The University of Adelaide, North Terrace Campus, Adelaide, SA, 5005, Australia.Due, Clemence. The School of Psychology, Faculty of Medical and Health Sciences, The University of Adelaide, North Terrace Campus, Adelaide, SA, 5005, Australia.
AN  - 31342444
AU  - Hartley,
AU  - M.
AU  - Dorstyn,
AU  - D.
AU  - Due,
AU  - C.
DA  - Jul 24
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10803-019-04145-3
DP  - Ovid Technologies
J2  - J Autism Dev Disord
L1  - internal-pdf://0460735190/Hartley-2019.pdf
LA  - English
N1  - Using Smart Source ParsingJulHartley, MatthewDorstyn, DianaDue, Clemence
PY  - 2019
SP  - 24
T2  - Journal of Autism &amp; Developmental Disorders
TI  - Mindfulness for Children and Adults with Autism Spectrum Disorder and Their Caregivers: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31342444
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31342444&amp;id=doi:10.1007%2Fs10803-019-04145-3&amp;issn=0162-3257&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2019&amp;title=Journal+of+Autism+%26+Developmental+Disorders&amp;atitle=Mindfulness+for+Children+and+Adults+with+Autism+Spectrum+Disorder+and+Their+Caregivers%3A+A+Meta-analysis.&amp;aulast=Hartley&amp;pid=%3Cauthor%3EHartley+M%3C%2Fauthor%3E%3CAN%3E31342444%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10803-019-04145-3
VL  - 24
ER  -
TY  - JOUR
AB  - **Background**
Attention deficit hyperactivity disorder (ADHD) in children is associated with hyperactivity and impulsivity, attention problems, and difficulties with social interactions. Pharmacological treatment may alleviate the symptoms of ADHD but this rarely solves difficulties with social interactions. Children with ADHD may benefit from interventions designed to improve their social skills. We examined the benefits and harms of social skills training on social skills, emotional competencies, general behaviour, ADHD symptoms, performance in school of children with ADHD, and adverse events.

**Objectives**
To assess the beneficial and harmful effects of social skills training in children and adolescents with ADHD.Search methodsIn July 2018, we searched CENTRAL, MEDLINE, Embase, PsycINFO, 4 other databases and two trials registers.We also searched online conference abstracts, and contacted experts in the field for information about unpublished or ongoing randomised clinical trials. We did not limit our searches by language, year of publication, or type or status of publication, and we sought translation of the relevant sections of non‐English language articles.

**Selection criteria**
Randomised clinical trials investigating social skills training versus either no intervention or waiting‐list control, with or without pharmacological treatment of both comparison groups of children and adolescents with ADHD.

**Data collection and analysis**
We conducted the review in accordance with the Cochrane Handbook for Systematic Reviews of Intervention. We performed the analyses using Review Manager 5 software and Trial Sequential Analysis. We assessed bias according to domains for systematic errors. We assessed the certainty of the evidence with the GRADE approach.

**Main results**
We included 25 randomised clinical trials described in 45 reports. The trials included a total of 2690 participants aged between five and 17 years. In 17 trials, participants were also diagnosed with various comorbidities.The social skills interventions were described as: 1) social skills training, 2) cognitive behavioural therapy, 3) multimodal behavioural/psychosocial therapy, 4) child life and attention skills treatment, 5) life skills training, 6) the &quot;challenging horizon programme&quot;, 7) verbal self‐instruction, 8) meta‐cognitive training, 9) behavioural therapy, 10) behavioural and social skills treatment, and 11) psychosocial treatment. The control interventions were no intervention or waiting list.The duration of the interventions ranged from five weeks to two years. We considered the content of the social skills interventions to be comparable and based on a cognitive‐behavioural model. Most of the trials compared child social skills training or parent training combined with medication versus medication alone. Some of the experimental interventions also included teacher consultations. More than half of the trials were at high risk of bias for generation of the allocation sequence and allocation concealment. No trial reported on blinding of participants and personnel. Most of the trials did not report on differences between groups in medication for comorbid disorders. We used all eligible trials in the meta‐analyses, but downgraded the certainty of the evidence to low or very low.We found no clinically relevant treatment effect of social skills interventions on the primary outcome measures: teacher‐rated social skills at end of treatment (standardised mean difference (SMD) 0.11, 95% confidence interval (CI) 0.00 to 0.22; 11 trials, 1271 participants; I2 = 0%; P = 0.05); teacher‐rated emotional competencies at end of treatment (SMD &minus;0.02, 95% CI &minus;0.72 to 0.68; two trials, 129 participants; I2 = 74%; P = 0.96); or on teacher‐rated general behaviour (SMD &minus;0.06 (negative value better), 95% CI &minus;0.19 to 0.06; eight trials, 1002 participants; I2 = 0%; P = 0.33). The effect on the primary outcome, teacher‐rated social skills at end of treatment, corresponds to a MD of 1.22 points on the social skills rating system (SSRS) scale (95% CI 0.09 to 2.36). The minimal clinical relevant difference (10%) on the SSRS is 10.0 points (range 0 to 102 points on SSRS).We found evidence in favour of social skills training on teacher‐rated core ADHD symptoms at end of treatment for all eligible trials (SMD &minus;0.26, 95% CI &minus;0.47 to &minus;0.05; 14 trials, 1379 participants; I2= 69%; P = 0.02), but the finding is questionable due to lack of support from sensitivity analyses, high risk of bias, lack of clinical significance, high heterogeneity, and low certainty.The studies did not report any serious or non‐serious adverse events.

**Authors&#039; conclusions**
The review suggests that there is little evidence to support or refute social skills training for children and adolescents with ADHD. We may need more trials that are at low risk of bias and a sufficient number of participants to determine the efficacy of social skills training versus no training for ADHD. The evidence base regarding adolescents is especially weak.
AU  - Storebø,
AU  - O.
AU  - J.
AU  - Andersen,
AU  - M.
AU  - E.
AU  - Skoog,
AU  - M.
AU  - Hansen,
AU  - S.
AU  - J.
AU  - Simonsen,
AU  - E.
AU  - Pedersen,
AU  - N.
AU  - Tendal,
AU  - B.
AU  - Callesen,
AU  - H.
AU  - E.
AU  - Faltinsen,
AU  - E.
AU  - Gluud,
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD008223.pub3
L1  - internal-pdf://3232744914/Storebø-2019-Social skills training for attent.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years
ER  -
TY  - JOUR
AB  - **Background and Objectives:** 
Recent studies have shown the existence of a positive relationship between physical exercise, symptomatic improvement, and reduction of damage caused by comorbidities associated with autistic spectrum disorder (ASD) in children, adolescents, and adults. The aim of this systematic review with meta-analysis (SRM) was to estimate the effects of physical exercise (PE) on the stereotyped behaviors of children with a diagnosis of ASD in intervention studies. 

**Materials and Methods:** 
The design followed the PRISMA guidelines and the TREND statement to assess the quality of information in each study. Nine non-randomized intervention trial studies with low, moderate, and vigorous physical exercise, with a duration varying from 8 to 48 weeks and a frequency of 3 times a week, were included in the SRM. The dependent variable episodes of stereotypical behaviors was analyzed in all studies and assessed as the number of episodes demonstrated by the child in pre- versus post-exercise intervention conditions. 

**Results:** 
The eight studies included a total 129 children (115 males and 14 females) with an average age of 8.93 &plusmn; 1.69 years. Children with ASD showed a reduction of 1.1 in the number of occurrences of stereotypical behaviors after intervention with physical exercise. 

**Conclusion:** 
Evidence was found to support physical exercise as an effective tool in reducing the number of episodes of stereotypical behaviors in children diagnosed with ASD.
AD  - Ferreira, Jose Pedro. Sport and Physical Activity Research Center (CIDAF), University of Coimbra, 3040-156 Coimbra, Portugal. jpferreira@fcdef.uc.pt.Ghiarone, Thaysa. Statistic Department, Federal University of Alagoas, Maceio CEP 57072-970, Brazil.Junior, Cyro Rego Cabral. Health Sciences Department, Federal University of Pernambuco, Recife CEP 50670-901, Brazil.Furtado, Guilherme Eustaquio. Sport and Physical Activity Research Center (CIDAF), University of Coimbra, 3040-156 Coimbra, Portugal.Carvalho, Humberto Moreira. Faculty of Physical Education, Federal University of Santa Catarina, Florianopolis CEP 88040-900, Brazil.Rodrigues, Aristides Machado. High School of Education, Polytechnic Institute of Viseu, 3504-501 Viseu, Portugal.Toscano, Chrystiane Vasconcelos Andrade. Sport and Physical Activity Research Center (CIDAF), University of Coimbra, 3040-156 Coimbra, Portugal.Toscano, Chrystiane Vasconcelos Andrade. Department of Physical Education, Federal University of Alagoas, Maceio CEP 57072-970, Brazil.
AN  - 31615098
AU  - Ferreira,
AU  - J.
AU  - P.
AU  - Ghiarone,
AU  - T.
AU  - Junior,
AU  - C.
AU  - R.
AU  - C.
AU  - Furtado,
AU  - G.
AU  - E.
AU  - Carvalho,
AU  - H.
AU  - M.
AU  - Rodrigues,
AU  - A.
AU  - M.
AU  - Toscano,
AU  - C.
AU  - V.
AU  - A.
DA  - Oct 14
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3390/medicina55100685
DP  - Ovid Technologies
J2  - Medicina (Kaunas)
L1  - internal-pdf://1060136110/Ferreira-2019-Effects of Physical Exercise on.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingOctFerreira, Jose PedroGhiarone, ThaysaJunior, Cyro Rego CabralFurtado, Guilherme EustaquioCarvalho, Humberto MoreiraRodrigues, Aristides MachadoToscano, Chrystiane Vasconcelos AndradeE685
PY  - 2019
SP  - 14
T2  - Medicina
TI  - Effects of Physical Exercise on the Stereotyped Behavior of Children with Autism Spectrum Disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31615098
UR  - https://res.mdpi.com/d_attachment/medicina/medicina-55-00685/article_deploy/medicina-55-00685-v2.pdf
VL  - 55
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Irritability is common in pediatric autism spectrum disorder (ASD) patients. This can have major implications in child development, receptivity to behavioral therapy, as well as child and caregiver well-being. A systematic review and network meta-analysis were conducted to assess the efficacy and safety of atypical antipsychotics in treating irritability in these patients. 

**METHODS: **
Studies were identified from Medline, Embase, and PsycINFO from inception to March 2018. The clinical trials database was reviewed. Studies were included if they were a double-blind, randomized controlled trial utilizing the Aberrant Behavior Checklist Irritability (ABC-I) to measure the efficacy of atypical antipsychotic monotherapy. Data extraction was carried out following the Preferred Reporting Items for Systematic Reviews and Meta-analyses for network meta-analysis guidelines. The main outcome was the reduction in irritability score using the ABC-I subscale from baseline. 

**RESULTS: **
Eight trials comparing four interventions-risperidone, aripiprazole, lurasidone, and placebo in 878 patients, were included. Both risperidone and aripiprazole had significantly reduced ABC-I scores than placebo. Estimates of mean differences (95% credible intervals) were risperidone, -6.89 (-11.14, -2.54); aripiprazole, -6.62 (-10.88, -2.22); and lurasidone, -1.61 (-9.50, 6.23). Both risperidone and aripiprazole had similar safety. There were only eight studies included in the analysis, however, sample sizes were not small. Variance in reporting of adverse effects limited the quality of safety analysis. 

**CONCLUSION: **
Risperidone and aripiprazole were the two best drugs, with comparable efficacy and safety in pediatric ASD patients. These two medications could be beneficial in improving irritability in these patients.
AN  - 30707602
AU  - Fallah,
AU  - M.
AU  - S.
AU  - Shaikh,
AU  - M.
AU  - R.
AU  - Neupane,
AU  - B.
AU  - Rusiecki,
AU  - D.
AU  - Bennett,
AU  - T.
AU  - A.
AU  - Beyene,
AU  - J.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1089/cap.2018.0115
L1  - internal-pdf://0726866256/Fallah-2019-Atypical Antipsychotics for Irrita.pdf
PY  - 2019
SP  - 01
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Atypical Antipsychotics for Irritability in Pediatric Autism: A Systematic Review and Network Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30707602
VL  - 01
ER  -
TY  - JOUR
AB  - A growing number of studies have investigated technology-based interventions (computer, phone, tablet, robot, etc.) for supporting children and teenagers with ASD, notably in school settings. Past reviews stressed study design weaknesses of TBI researches. 

This systematic review has threefold purpose: 1) to update the previous ones with a focus on clinical-quality studies; 2) to examine reliability, consistency, durability and generalization of measurements; and 3) to compare the methodology of two cores of studies according to two dimensions: Therapeutic Effectiveness (TE) and Technology Usability (TU). 

From the 685 search results, 31 studies were selected (22 on TE, 6 on TU, and 3 on TE-TU). Overall, few studies reached the standards of evidence-based practices (reliability, consistency, durability, generalization). TE studies provided more evidence of their reliability than TU and TU-TE studies. 

Moreover, the examination of studies&#039; results revealed that: 1) the more robust study designs, the less consistent TBI effect, 2) the more reliable the measure, the less large TBI-related effect size. Although less robust, TE-TU studies can be seen as an emerging interdisciplinary approach, combining expertise in human-computer interaction and clinical research.
AN  - WOS:000457666400026
AU  - Mazon,
AU  - C.
AU  - Fage,
AU  - C.
AU  - Sauzeon,
AU  - H.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1016/j.chb.2018.12.001
L1  - internal-pdf://0999627931/Mazon-2019-Effectiveness and usability of tech.pdf
PY  - 2019
SP  - 235-251
T2  - Computers in Human Behavior
TI  - Effectiveness and usability of technology-based interventions for children and adolescents with ASD: A systematic review of reliability, consistency, generalization and durability related to the effects of intervention
UR  - &lt;Go to ISI&gt;://WOS:000457666400026
UR  - https://ac.els-cdn.com/S0747563218305879/1-s2.0-S0747563218305879-main.pdf?_tid=44f6cc00-5062-47b1-a99e-3fe532eb63b3&amp;acdnat=1551877686_35491f913820d19b998a0372da5dc19d
VL  - 93
ER  -
TY  - JOUR
AB  - **PURPOSE: **
Childhood chronic conditions have a considerable effect on the quality of life (QoL) of pediatric patients and their caregivers. The purpose of this meta-analysis was to evaluate the effects of caregiver-involved interventions on the QoL of children and adolescents with chronic conditions and their caregivers. 

**METHODS: **
The PubMed, EMBASE, Web of Science, Cumulative Index of Nursing and Allied Health Literature, Academic Search Complete, Education Resource Information Center, and PsycINFO databases were searched for published randomized controlled trials from inception to April 2016. Two reviewers (NS and JM) independently screened included studies and assessed study quality. The meta-analyses and meta-regressions using random-effects models were performed with the Comprehensive Meta-analysis software (version 3, Biostat, Englewood, NJ). 

**RESULTS: **
Fifty-four studies involving 10075 pediatric patients diagnosed with asthma, diabetes, cancer, hypersensitivity, cerebral palsy, arthritis, or sickle cell diseases and 10015 caregivers were included in our analysis. The interventions mainly involved education about disease, skill training, environment change, psychological intervention, physical exercise, experience sharing, monitoring, or social support. The results demonstrated that caregiver-involved interventions significantly improved the health-related QoL (HRQoL) of caregivers [standardized mean difference (SMD) = 0.26, 95% CI 0.14-0.38, p &lt; 0.001], particularly those delivered through the face-to-face mode (SMD = 0.32, 95% CI 0.21-0.43, p &lt; 0.001). However, no improvements in the QoL (SMD = 0.00, 95% CI - 0.22 to 0.22, p = 1.00) and HRQoL (SMD = 0.06, 95% CI - 0.02 to 0.14, p = 0.16) of children and both caregivers and children (SMD = 0.04, 95% CI - 0.08 to 0.17, p = 0.52) were observed. 

**CONCLUSIONS: **
This meta-analysis provides evidence on the positive effects of caregiver-involved interventions on the HRQoL of caregivers. Moreover, face-to-face mode is the delivery approach with a promising effect on the HRQoL of caregivers. Further research on conditions not found in this review is warranted.
AN  - 30167936
AU  - Sheng,
AU  - N.
AU  - Ma,
AU  - J.
AU  - Ding,
AU  - W.
AU  - Zhang,
AU  - Y.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s11136-018-1976-3
L1  - internal-pdf://2111774448/Sheng-2019-Effects of caregiver-involved inter.pdf
PY  - 2019
SP  - 13-33
T2  - Quality of Life Research
TI  - Effects of caregiver-involved interventions on the quality of life of children and adolescents with chronic conditions and their caregivers: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30167936
UR  - https://link.springer.com/article/10.1007%2Fs11136-018-1976-3
VL  - 28
ER  -
TY  - JOUR
AB  - **BACKGROUND AND AIMS:** 
Although the peculiarities of problematic Internet use and Internet addiction have been analyzed previously by researchers, there is still no general agreement in the literature as to the effectiveness of psychological interventions for Internet addiction deployed among adolescents. This study sought to investigate the effects of intervention programs for Internet/smartphone addiction among adolescents through a meta-analysis.

**METHODS:**
We searched MEDLINE (PubMed), EbscoHost Academic Search Complete, ProQuest, and PsycARTICLES using a combination of &quot;Internet addiction or phone addiction&quot; AND &quot;intervention or treatment&quot; OR &quot;therapy&quot; OR &quot;program&quot; AND &quot;adolescents,&quot; and a combination of the following search terms: &quot;patholog_,&quot; &quot;problem_,&quot; &quot;addict_,&quot; &quot;compulsive,&quot; &quot;dependen_,&quot; &quot;video,&quot; &quot;computer,&quot; &quot;Internet,&quot; &quot;online,&quot; &quot;intervention,&quot; &quot;treat_,&quot; and &quot;therap_.&quot; The studies identified during the search were reviewed according to the criteria and a meta-analysis was conducted on the six selected papers published from 2000 to 2019. Only studies with a control/comparison group that performed preintervention and postintervention assessments were included.

**RESULTS:** 
Included studies showed a trend toward a beneficial effect of intervention on the severity of Internet addictions. The meta-analysis suggested significant effects of all included randomized controlled trials (RCTs) and their educational programs.

**CONCLUSIONS:**
Psychological interventions may help to reduce addiction severity, but further RCTs are needed to identify the effectiveness of cognitive behavioral therapy. This study provides a basis for developing future programs addressing addiction problems among adolescents.
AD  - Malinauskas, Romualdas. Department of Health, Physical and Social Education, Lithuanian Sports University, Kaunas, Lithuania.Malinauskiene, Vilija. Department of Health, Physical and Social Education, Lithuanian Sports University, Kaunas, Lithuania.
AN  - 31891316
AU  - Malinauskas,
AU  - R.
AU  - Malinauskiene,
AU  - V.
DA  - Dec
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1556/2006.8.2019.72
DP  - Ovid Technologies
J2  - J
L1  - internal-pdf://3624675639/Malinauskas.pdf
LA  - English
N1  - Malinauskas, RomualdasMalinauskiene, Vilija
PY  - 2019
SP  - 613-624
T2  - Journal of Behavioral Addictions
TI  - A meta-analysis of psychological interventions for Internet/smartphone addiction among adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31891316
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31891316&amp;id=doi:10.1556%2F2006.8.2019.72&amp;issn=2062-5871&amp;isbn=&amp;volume=8&amp;issue=4&amp;spage=613&amp;pages=613-624&amp;date=2019&amp;title=Journal+of+Behavioral+Addictions&amp;atitle=A+meta-analysis+of+psychological+interventions+for+Internet%2Fsmartphone+addiction+among+adolescents.&amp;aulast=Malinauskas&amp;pid=%3Cauthor%3EMalinauskas+R%3C%2Fauthor%3E%3CAN%3E31891316%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 8
ER  -
TY  - JOUR
AB  - Many trials have provided support for dissonance-based eating disorder prevention programs. This meta-analytic review characterized the average intervention effects and tested whether various intervention, participant, and facilitator features correlated with larger effects to guide implementation of optimally effective versions of this program. 

We identified 56 trials that evaluated 68 dissonance-based eating disorder prevention programs (7808 participants). Average intervention effect sizes (d) relative to minimal intervention control conditions and credible alternative interventions (respectively) were 0.57 and 0.31 for thin-ideal internalization, 0.42 and 0.18 for body dissatisfaction, 0.37 and 0.17 for dieting, 0.29 and 0.21 for negative affect, and 0.31 and 0.13 for eating disorder symptoms. 

As hypothesized, effects were larger for interventions with more dissonance-inducing activities, more group sessions, and larger group sizes, as well as when delivered in-person versus on-line, sessions were recorded, participation was voluntary, body dissatisfaction was required, participants were mid-adolescents or adults (versus older adolescence), there were more ethnic minority participants, groups were led by clinicians versus researchers and at least two facilitators, and when facilitators received more training and supervision. Unexpectedly from a dissonance-induction perspective, effects were larger when participants were compensated.
AN  - 31004832
AU  - Stice,
AU  - E.
AU  - Marti,
AU  - C.
AU  - N.
AU  - Shaw,
AU  - H.
AU  - Rohde,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2019.04.004
L1  - internal-pdf://1208022175/Stice-2019-Meta-analytic review of dissonance-.pdf
PY  - 2019
SP  - 91-107
T2  - Clinical Psychology Review
TI  - Meta-analytic review of dissonance-based eating disorder prevention programs: Intervention, participant, and facilitator features that predict larger effects
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31004832
UR  - https://www.sciencedirect.com/science/article/pii/S0272735818300886?via%3Dihub
VL  - 70
ER  -
TY  - JOUR
AB  - Students with attention deficit hyperactivity disorder (ADHD) experience symptoms of inattention, impulsivity, and hyperactivity that often manifest as academic impairment. As such, teachers must select interventions to increase the probability of success for students with ADHD in their classes. Prior meta-analyses have evaluated school-based intervention effects; however, no systematic review meta-analysis has evaluated the effectiveness of interventions implemented in classrooms with students with ADHD. 

Additionally, classroom-based studies are frequently conducted through single-case design methodology, and recent advances in meta-analytic techniques provide the opportunity to explore intervention effectiveness as evaluated through quality research. Therefore, to inform selection of evidence-based interventions to be implemented in classroom settings, the current systematic review with meta-analysis of single-case design studies was conducted to evaluate intervention effectiveness, evidence-based status, and moderators of effects for four intervention types (behavioral, instructional, self-management, and environmental) when implemented with students with ADHD in classroom settings. 

The analysis included 27 articles published from 1971 to 2018. Overall and specific to each intervention type, the results indicate that classroom-based interventions for students with ADHD were moderately effective. Instructional and self-management interventions were deemed evidence based by What Works Clearinghouse standards and potentially evidence based by Council for Exceptional Children standards. Behavioral interventions were found to be potentially evidence based by Council for Exceptional Children criteria and were most effective when selected through functional behavior analysis and implemented by researchers in secondary settings. Instructional interventions were more effective when implemented in special education settings targeting academic outcomes. Implications for research and practice are discussed.
AN  - WOS:000473501100001
AU  - Harrison,
AU  - J.
AU  - R.
AU  - Soares,
AU  - D.
AU  - A.
AU  - Rudzinski,
AU  - S.
AU  - Johnson,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3102/0034654319857038
L1  - internal-pdf://1021812796/Harrison-2019-Attention Deficit Hyperactivity.pdf
PY  - 2019
SP  - 569-611
T2  - Review of Educational Research
TI  - Attention Deficit Hyperactivity Disorders and Classroom-Based Interventions: Evidence-Based Status, Effectiveness, and Moderators of Effects in Single-Case Design Research
UR  - &lt;Go to ISI&gt;://WOS:000473501100001
VL  - 89
ER  -
TY  - JOUR
AB  - **Background**
Care farming (also called social farming) is the therapeutic use of agricultural and farming practices. Service users and communities supported through care farming include people with learning disabilities, people with mental and physical health problems, people with substance misuse problems, adult offenders, disaffected youth, socially isolated older people and the long‐term unemployed. Care farming is a highly complex intervention that can involve different farming activities (horticulture, forestry or livestock farming) or other activities (gardening, conservation or woodwork), with different levels of support provided according to the needs of the individual service users. Likewise the service users can contribute to farming production or the farm itself may focus on the provision of care services. Care farming sits within a broader framework of similar nature based supportive interventions collectively terms green care that also includes wilderness therapy, social and therapeutic horticulture, environmental conservation and green exercise. There are around 1,100 CFs in The Netherlands, 900 in France, 675 in Italy and 669 in Belgium. In the UK and Ireland (both the Republic and the North) numbers are fewer with around 230 and 100, respectively. With increasing pressure on the health and social care sector, commissioners are turning to green care interventions as an alternative approach. Although a number of overviews and one systematic review of care farming exists there is a need for a review that captures the full range of published and grey literature, and to explore in depth the mechanisms that explain how care farming works for different service user groups.

**Objectives**
The primary objective was to systematically review the available evidence of the effects of CFs on quality of life, health and social well‐being on service users. Within this, we aimed to explore the size of the effect that CFs have on the health, well‐being and social outcomes of different population groups. With available material we also aimed to explore the relationship between contextual data (the activities and characteristics of the farm and the nature of the service user groups) and the impact on outcomes. Finally, we aimed to understand the mechanisms of change for different population groups with a view to constructing a logic model to describe the ways in which care farming might work.

**Search methods**
In 2015, we searched 22 health, education, environmental, criminal justice and social science electronic databases. We also searched databases of grey literature, and various websites, including care farming websites across a number of European countries. Reference lists of included studies and identified systematic reviews were scanned, and citations of key papers were tracked using Google Scholar and Web of Science Citation Indices. This was supplemented by hand searching the Wageningen Journal of Life Sciences from 2000 onwards and by contacting academic and care farming networks to identify any other reports. Our search terms were deliberately broad to capture all rehabilitative interventions occurring on farm and farm type settings. The search of electronic databases as repeated in 2017, due to limited resources the grey literature search was not repeated in 2017.

**Selection criteria**
We included a broad range of study designs: RCTs and quasi‐RCTs; interrupted time series and nonrandomised controlled observational studies; uncontrolled before and after studies and qualitative studies. We excluded single subject designs, reviews, overviews, surveys, commentaries and editorials. Study participants were those that typically receive support at a CF, including but not restricted to people with mental health problems, learning difficulties, health problems, substance misuse problems, and offenders and disaffected youth. Only those attending for a single day as a visitor were excluded. Studies conducted in a setting that met the accepted definition of a CF were included, but farming interventions that were carried out in a hospital or prison setting were excluded. For the purposes of developing the logic model, we retained papers that described any theories to explain how and for whom care farming might work. These papers are not formally included in the review.

**Data collection and analysis**
Each screening stage involved two independent reviewers. Studies that were potentially eligible after title and abstract screening underwent full paper screening. Disagreements were discussed and resolved by consensus at each stage. Papers describing theories in relation to care farming were separately retained even if they did not meet the inclusion criteria for the purposes of constructing a theoretical framework to inform the logic models. The Preferred Reporting Items for Systematic Reviews and Meta‐Analysis (PRISMA) was used to state the process of study selection. We stored all references in Endnote (VX7) and recorded extracted data and the outcomes of full paper screening in EPPI‐Reviewer 4 (V.4.5.0.1). The data extraction form was based on the CPHG Data Extraction and Assessment Template with subsections for contextual information, and qualitative and quantitative data. We used a sequential exploratory approach to the review involving four stages: (a) developing a theoretical framework; (b) identifying the intervention components, mechanisms of change, and proximal outcomes from existing theories and qualitative data; (c) mapping the mechanisms of change and proximal outcomes to the theories to develop the logic models and (d) testing the logic models against the quantitative data. We used an adapted version of the COREQ tool to assess the quality of the qualitative studies, and the EPOC and EPHPP tools to assess the risk of bias in quantitative studies. No studies were excluded based on quality. The nature of the studies meant that we were unable to assess treatment effect and reporting biases.2.6 ResultsIn 2015, our search methods identified 1,659 articles, of which 14 qualitative studies, 13 quantitative studies and one mixed methods study met the inclusion criteria. In addition, we identified 15 theories that had been quoted in connection with care farming. The rerun of the search of publish literature in July 2017 identified a further 391 articles, of which three qualitative studies met the inclusion criteria. The total studies in this review are 18 qualitative studies and 13 quantitative studies, one of which was a mixed‐methods study. We created four logical models to explain how care farming might work: an overall one for all service user groups; one for people with either mental health problems or substance misuse problems, one for disaffected youth and one for people with learning disabilities. These models comprised five key theoretical concepts derived from identified theories (restorative effects of nature, being socially connected, personal growth, physical well‐being and mental well‐being), five categories of intervention components (being in a group, the farmer, the work, the animals and the setting) and 15 categories of mechanisms derived from included qualitative studies (achievement and satisfaction, belonging and nonjudgement, creating a new identity, distraction, feeling valued and respected, feeling safe, learning skills, meaningfulness, nurturing, physical well‐being, reflection, social relationships, stimulation, structure, and understanding the self). In addition, from the theories and qualitative studies, we identified 12 different outcomes, both proximal (secondary) and primary, that we expected to find when testing the logic models against the quantitative studies. One key theoretical concept &ldquo;restorative effects of nature&rdquo; was underrepresented in the intervention components and mechanisms reported within the qualitative studies. The types of mechanisms appeared to differ according to different service user groups, suggesting that care farming may work in different ways according to different needs. Across the 13 quantitative studies (including the mixed methods study), 24 different outcome measures were reported. Eight studies (both qualitative and quantitative) reported results for mixed client groups. Only the logic model for mental illness and substance misuse was tested, due to a lack of quantitative evaluations for the other service user groups. We found a lack of evidence to indicate that CFs improve quality of life, and limited evidence that they might improve depression and anxiety. There was some evidence to suggest that CFs can improve self‐efficacy, self‐esteem and mood, with inconsistent evidence of benefit for social outcomes. All of the studies had a high risk of bias so the results should be treated with caution.

**Authors&rsquo; conclusions**
There is a lack of evidence available to determine whether or not care farming is effective in improving quality of life, depression and anxiety. More evidence is available for those with mental ill‐health, but firm conclusions cannot be drawn. Small study sizes of poor design, evaluations involving mixed service user groups, the use of multiple and sometimes unvalidated outcome measures, short follow‐ups, and the absence of key outcomes that fit with theory have all hampered the development of a more robust evidence base. However, we now have a set of theory‐based logic models that offer a framework for research evaluations. With recommendations in place to address the current research inadequacies there is an opportunity to vastly improve the evidence base for care farming.Despite the current lack of robust evidence to support the effectiveness of care farming, there are strong arguments to support a more integrated approach to care farming as a viable alternative or adjunct to mainstream approaches for mental health problems. Lack of choice, gender inequalities and over‐burdened statutory services indicate the need for a credible alternative treatment option. A concerted effort to increase awareness among commissioners of health care, frontline service providers, and potential service users about care farming, how, and for whom, it might work is needed. Models across Europe that offer a more integrated approach between green care and statutory services could provide valuable learning. The evidence for care farming for other service user groups is not as well developed as it is for those with mental health problems, but that is not to say there is not a need. Disaffected youth, adult offenders and people with dementia represent significantly large vulnerable population groups where current service provisions struggles to meet demand. The need to continue to improve and provide high quality research in these areas is, therefore, pressing.
AU  - Murray,
AU  - J.
AU  - Wickramasekera,
AU  - N.
AU  - Elings,
AU  - M.
AU  - Bragg,
AU  - R.
AU  - Brennan,
AU  - C.
AU  - Richardson,
AU  - Z.
AU  - Wright,
AU  - J.
AU  - Llorente,
AU  - M.
AU  - Cade,
AU  - J.
AU  - Shickle,
AU  - D.
AU  - Tubeuf,
AU  - S.
AU  - Elsey,
AU  - H.
DA  - 26. Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://doi.org/10.1002/cl2.1061
PY  - 2019
T2  - Campbell Systematic Reviews
TI  - The impact of care farms on quality of life, depression and anxiety among different population groups: A systematic review
ER  -
TY  - JOUR
AB  - In the present meta-analysis all available evidence regarding the efficacy of different behavioral interventions for children&#039;s executive function skills were synthesized. After a systematic search we included experimental studies aiming to enhance children&#039;s (up to 12 years of age) executive functioning with neurodevelopmental tests as outcome measures. 

The results of 100 independent effect sizes in 90 studies including data of 8,925 children confirmed that it is possible to foster these skills in childhood (Diamond &amp; Lee, 2011). We did not find convincing evidence, however, for the benefits to remain on follow-up assessment. Different approaches were effective for typically and nontypically developing samples. 

For nontypically developing children (including children with neurodevelopmental disorders or behavior problems) acquiring new strategies of self-regulation including biofeedback-enhanced relaxation and strategy teaching programs were the most effective. For typically developing children we found evidence for the moderate beneficial effects of mindfulness practices.

Although small to moderate effects of explicit training with tasks loading on executive function skills in the form of computerized and noncomputer training were found, these effects were consistently weaker for nontypically developing children who might actually be more in need of such training. 

Thus, atypically developing children seem to profit more from acquiring new strategies of self-regulation as compared with practice with executive function tasks. We propose that explicit training does not seem to be meaningful as the approaches that implicitly foster executive functions are similarly or more effective, and these activities are more enjoyable and can be more easily embedded in children&#039;s everyday activities. 

(PsycINFO Database Record (c) 2019 APA, all rights reserved).
AN  - 31033315
AU  - Takacs,
AU  - Z.
AU  - K.
AU  - Kassai,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/bul0000195
L1  - internal-pdf://2683541210/Takacs-2019-The efficacy of different interven.pdf
PY  - 2019
SP  - 29
T2  - Psychological Bulletin
TI  - The efficacy of different interventions to foster children&#039;s executive function skills: A series of meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31033315
VL  - 29
ER  -
TY  - JOUR
AB  - **Aim:**
Pediatric Anxiety Disorders (AD) are common. Cognitive behavioral therapy (CBT) is one of two first-line treatments of youth AD and it has previously been shown to be superior to wait-list but not placebo therapy. This study consists of a systematic review and meta-analysis of the literature to assess the efficacy of CBT modalities in comparison to control contingencies for pediatric anxiety disorders.

**Methods:**
 Studies were included if they were randomized controlled trials, and if CBT was manualized or modular, alone or in combination with medication. CBT was required to include behavioral treatment, exposure treatment, or cognitive elements. Eligible studies included participants aged 18 years or younger.

**Results:**
Eighty-one studies were included, with 3386 CBT participants and 2527 control participants. The overall results indicated that CBT is an effective treatment for childhood AD. The results showed that individual-based CBT is superior to wait-list and attention control. Group-based CBT is superior to wait-list control and treatment as usual. Remote-based CBT was superior to attention control and wait-list control. Family-based CBT was superior to treatment as usual, wait-list control, and attention control. Selective serotonin reuptake inhibitors were no more effective than individual-based CBT. Combination treatment was, however, more effective than individual-based CBT.

**Conclusion:** 
To the best of our knowledge, no meta-analysis has thus far disentangled the effects of CBT modalities across various comparisons. This meta-analysis hence provides an important update to the literature on the efficacy of CBT for treating anxiety disorders in young people.
AD  - Sigurvinsdottir, Anna Lilja. The Health Care Institution of North Iceland, Akureyri, Iceland.Jensinudottir, Kolbrun Bjork. Faculty of Psychology, University of Iceland, Reykjavik, Iceland.Baldvinsdottir, Karen Dogg. Landspitali - the National University Hospital of Iceland, Reykjavik, Iceland.Smarason, Orri. Faculty of Psychology, University of Iceland, Reykjavik, Iceland.Smarason, Orri. Landspitali - the National University Hospital of Iceland, Reykjavik, Iceland.Skarphedinsson, Gudmundur. Faculty of Psychology, University of Iceland, Reykjavik, Iceland.
AN  - 31738631
AU  - Sigurvinsdottir,
AU  - A.
AU  - L.
AU  - Jensinudottir,
AU  - K.
AU  - B.
AU  - Baldvinsdottir,
AU  - K.
AU  - D.
AU  - Smarason,
AU  - O.
AU  - Skarphedinsson,
AU  - G.
DA  - Nov 18
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/08039488.2019.1686653
DP  - Ovid Technologies
J2  - Nord J Psychiatry
L1  - internal-pdf://1875334426/Sigurvinsdottir 2019 (1).pdf
LA  - English
N1  - Sigurvinsdottir, Anna LiljaJensinudottir, Kolbrun BjorkBaldvinsdottir, Karen DoggSmarason, OrriSkarphedinsson, Gudmundur
PY  - 2019
SP  - 1-13
T2  - Nordic Journal of Psychiatry
TI  - Effectiveness of cognitive behavioral therapy (CBT) for child and adolescent anxiety disorders across different CBT modalities and comparisons: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31738631
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31738631&amp;id=doi:10.1080%2F08039488.2019.1686653&amp;issn=0803-9488&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-13&amp;date=2019&amp;title=Nordic+Journal+of+Psychiatry&amp;atitle=Effectiveness+of+cognitive+behavioral+therapy+%28CBT%29+for+child+and+adolescent+anxiety+disorders+across+different+CBT+modalities+and+comparisons%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Sigurvinsdottir&amp;pid=%3Cauthor%3ESigurvinsdottir+AL%3C%2Fauthor%3E%3CAN%3E31738631%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/full/10.1080/08039488.2019.1686653
ER  -
TY  - JOUR
AB  - **Background**
This review represents one from a family of three reviews focusing on interventions for drug‐using offenders. Many people under the care of the criminal justice system have co‐occurring mental health problems and drug misuse problems; it is important to identify the most effective treatments for this vulnerable population.

**Objectives**
To assess the effectiveness of interventions for drug‐using offenders with co‐occurring mental health problems in reducing criminal activity or drug use, or both.This review addresses the following questions.
&bull; Does any treatment for drug‐using offenders with co‐occurring mental health problems reduce drug use?
&bull; Does any treatment for drug‐using offenders with co‐occurring mental health problems reduce criminal activity?
&bull; Does the treatment setting (court, community, prison/secure establishment) affect intervention outcome(s)?
&bull; Does the type of treatment affect treatment outcome(s)?

**Search methods**
We searched 12 databases up to February 2019 and checked the reference lists of included studies. We contacted experts in the field for further information.Selection criteriaWe included randomised controlled trials designed to prevent relapse of drug use and/or criminal activity among drug‐using offenders with co‐occurring mental health problems.

**Data collection and analysis**
We used standard methodological procedures as expected by Cochrane .Main resultsWe included 13 studies with a total of 2606 participants. Interventions were delivered in prison (eight studies; 61%), in court (two studies; 15%), in the community (two studies; 15%), or at a medium secure hospital (one study; 8%). Main sources of bias were unclear risk of selection bias and high risk of detection bias.Four studies compared a therapeutic community intervention versus (1) treatment as usual (two studies; 266 participants), providing moderate‐certainty evidence that participants who received the intervention were less likely to be involved in subsequent criminal activity (risk ratio (RR) 0.67, 95% confidence interval (CI) 0.53 to 0.84) or returned to prison (RR 0.40, 95% CI 0.24 to 0.67); (2) a cognitive‐behavioural therapy (one study; 314 participants), reporting no significant reduction in self‐reported drug use (RR 0.78, 95% CI 0.46 to 1.32), re‐arrest for any type of crime (RR 0.69, 95% CI 0.44 to 1.09), criminal activity (RR 0.74, 95% CI 0.52 to 1.05), or drug‐related crime (RR 0.87, 95% CI 0.56 to 1.36), yielding low‐certainty evidence; and (3) a waiting list control (one study; 478 participants), showing a significant reduction in return to prison for those people engaging in the therapeutic community (RR 0.60, 95% CI 0.46 to 0.79), providing moderate‐certainty evidence.One study (235 participants) compared a mental health treatment court with an assertive case management model versus treatment as usual, showing no significant reduction at 12 months&#039; follow‐up on an Addictive Severity Index (ASI) self‐report of drug use (mean difference (MD) 0.00, 95% CI ‐0.03 to 0.03), conviction for a new crime (RR 1.05, 95% CI 0.90 to 1.22), or re‐incarceration to jail (RR 0.79, 95% CI 0.62 to 1.01), providing low‐certainty evidence.Four studies compared motivational interviewing/mindfulness and cognitive skills with relaxation therapy (one study), a waiting list control (one study), or treatment as usual (two studies). In comparison to relaxation training, one study reported narrative information on marijuana use at three‐month follow‐up assessment. Researchers reported a main effect &lt; .007 with participants in the motivational interviewing group, showing fewer problems than participants in the relaxation training group, with moderate‐certainty evidence. In comparison to a waiting list control, one study reported no significant reduction in self‐reported drug use based on the ASI (MD ‐0.04, 95% CI ‐0.37 to 0.29) and on abstinence from drug use (RR 2.89, 95% CI 0.73 to 11.43), presenting low‐certainty evidence at six months (31 participants). In comparison to treatment as usual, two studies (with 40 participants) found no significant reduction in frequency of marijuana use at three months post release (MD ‐1.05, 95% CI ‐2.39 to 0.29) nor time to first arrest (MD 0.87, 95% CI ‐0.12 to 1.86), along with a small reduction in frequency of re‐arrest (MD ‐0.66, 95% CI ‐1.31 to ‐0.01) up to 36 months, yielding low‐certainty evidence; the other study with 80 participants found no significant reduction in positive drug screens at 12 months (MD ‐0.7, 95% CI ‐3.5 to 2.1), providing very low‐certainty evidence.Two studies reported on the use of multi‐systemic therapy involving juveniles and families versus treatment as usual and adolescent substance abuse therapy. In comparing treatment as usual, researchers found no significant reduction up to seven months in drug dependence on the Drug Use Disorders Identification Test (DUDIT) score (MD ‐0.22, 95% CI ‐2.51 to 2.07) nor in arrests (RR 0.97, 95% CI 0.70 to 1.36), providing low‐certainty evidence (156 participants). In comparison to an adolescent substance abuse therapy, one study (112 participants) found significant reduction in re‐arrests up to 24 months (MD 0.24, 95% CI 0.76 to 0.28), based on low‐certainty evidence.One study (38 participants) reported on the use of interpersonal psychotherapy in comparison to a psychoeducational intervention. Investigators found no significant reduction in self‐reported drug use at three months (RR 0.67, 95% CI 0.30 to 1.50), providing very low‐certainty evidence. The final study (29 participants) compared legal defence service and wrap‐around social work services versus legal defence service only and found no significant reductions in the number of new offences committed at 12 months (RR 0.64, 95% CI 0.07 to 6.01), yielding very low‐certainty evidence.

**Authors&#039; conclusions**
Therapeutic community interventions and mental health treatment courts may help people to reduce subsequent drug use and/or criminal activity. For other interventions such as interpersonal psychotherapy, multi‐systemic therapy, legal defence wrap‐around services, and motivational interviewing, the evidence is more uncertain. Studies showed a high degree of variation, warranting a degree of caution in interpreting the magnitude of effect and the direction of benefit for treatment outcomes.
AU  - Perry,
AU  - A.;
AU  - Martyn‐St
AU  - James,
AU  - M.;
AU  - Burns,
AU  - L.;
AU  - Hewitt,
AU  - C.;
AU  - M
AU  - Glanville,
AU  - J;
AU  - Aboaja,
AU  - A.;
AU  - Thakkar,
AU  - P.;
AU  - Murthy,
AU  - K.;
AU  - Kumar,
AU  - S.;
AU  - Pearson,
AU  - C.;
AU  - Wright,
AU  - K.;
AU  - Swami,
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD010901.pub3
L1  - internal-pdf://0059431514/Perry_et_al-2019-Cochrane_Database_of_Systemat.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for drug‐using offenders with co‐occurring mental health problems
ER  -
TY  - JOUR
AB  - This study examined the benefit of psychosocial interventions on functional impairment in youth exposed to mass trauma. A random effects meta-analysis was used to estimate the overall effect in 15 intervention trials identified through a literature review. The moderator analysis examined how the effect of intervention differed across types of populations receiving the intervention (targeted or non-targeted samples), characteristics of intervention delivery (individual or group application and number of sessions), and the context of intervention administration (country income level). The results revealed a significant small effect on functional impairment (Hedges&#039; g = 0.33; 95%CI = (0.16; 0.50); p = 0.0011). None of the moderators explained the heterogeneity in intervention effect, perhaps due to the small number of trials. The effect of the interventions on functional impairment and on posttraumatic stress were positively correlated. The current analysis provides preliminary evidence that interventions can improve functioning in youth exposed to mass trauma, but the mechanisms, moderators, and duration of benefit are yet unknown. Copyright &copy; 2019, Springer Nature Switzerland AG.
AN  - 628319224
AU  - Pfefferbaum,
AU  - B.
AU  - Nitiema,
AU  - P.
AU  - Newman,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s40653-019-00266-0
L1  - internal-pdf://2778327704/Pfefferbaum-2019-The Effect of Interventions o.pdf
PY  - 2019
T2  - Journal of Child and Adolescent Trauma.
TI  - The Effect of Interventions on Functional Impairment in Youth Exposed to Mass Trauma: a Meta-Analysis
UR  - http://www.springer.com/psychology/child+%26+school+psychology/journal/40653
UR  - https://link.springer.com/article/10.1007%2Fs40653-019-00266-0
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Mindfulness based interventions (MBIs) are an increasingly popular way of attempting to improve the behavioural, cognitive and mental health outcomes of children and adolescents, though there is a suggestion that enthusiasm has moved ahead of the evidence base. Most evaluations of MBIs are either uncontrolled or nonrandomized trials. This meta-analysis aims to establish the efficacy of MBIs for children and adolescents in studies that have adopted a randomized, controlled trial (RCT) design. 

**METHODS:**
A systematic literature search of RCTs of MBIs was conducted up to October 2017. Thirty-three independent studies including 3,666 children and adolescents were included in random effects meta-analyses with outcome measures categorized into cognitive, behavioural and emotional factors. Separate random effects meta-analyses were completed for the seventeen studies (n = 1,762) that used an RCT design with an active control condition. 

**RESULTS: **
Across all RCTs we found significant positive effects of MBIs, relative to controls, for the outcome categories of Mindfulness, Executive Functioning, Attention, Depression, Anxiety/Stress and Negative Behaviours, with small effect sizes (Cohen&#039;s d), ranging from .16 to .30. However, when considering only those RCTs with active control groups, significant benefits of an MBI were restricted to the outcomes of Mindfulness (d = .42), Depression (d = .47) and Anxiety/Stress (d = .18) only. 

**CONCLUSIONS: **
This meta-analysis reinforces the efficacy of using MBIs for improving the mental health and wellbeing of youth as assessed using the gold standard RCT methodology. Future RCT evaluations should incorporate scaled-up definitive trial designs to further evaluate the robustness of MBIs in youth, with an embedded focus on mechanisms of action.
AN  - 30345511
AU  - Dunning,
AU  - D.
AU  - L.
AU  - Griffiths,
AU  - K.
AU  - Kuyken,
AU  - W.
AU  - Crane,
AU  - C.
AU  - Foulkes,
AU  - L.
AU  - Parker,
AU  - J.
AU  - Dalgleish,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.12980
L1  - internal-pdf://3678520203/Dunning-2019-Research Review_ The effects of m.pdf
PY  - 2019
SP  - 244-258
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Research Review: The effects of mindfulness-based interventions on cognition and mental health in children and adolescents - a meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30345511
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcpp.12980
VL  - 60
ER  -
TY  - JOUR
AB  - **Purpose: **
This overview of reviews analyses the existing evidence base of functional family therapy (FFT), which is a manualized, family-based intervention for youth with behavioral problems and their families. FFT has been implemented among youth aged 10-18 at risk of, or presenting with, behavioral problems such as delinquency, violence, substance abuse, sexual perpetration, and truancy.

**Method:**
A multipronged search was conducted across 15 databases, 10 websites, and expert contacts in February 2018. 

**Results: **
The search yielded 159 hits of which 31 were included and critically appraised. Included reviews were published between 1986 and 2018 and the number of included studies ranged from 1 to 18 (including 20-5,344 participants). Main effects of the intervention on core outcomes (recidivism and substance abuse) were modest and out-of-home placement was not reported. Secondary outcomes were also modest but generally positive. 

**Conclusions: **
Findings demonstrate that overall quality of reviews is low, which makes any certainties about FFT inconclusive; this overview provides a concise, valid, and methodologically sound synthesis of the research into FFT, which requires more rigorous investigation.
AN  - WOS:000458201300009
AU  - Weisman,
AU  - C.
AU  - B.
AU  - Montgomery,
AU  - P.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1177/1049731518792309
L1  - internal-pdf://1842881034/Weisman-2019-Functional Family Therapy (FFT) f.pdf
PY  - 2019
SP  - 333-346
T2  - Research on Social Work Practice
TI  - Functional Family Therapy (FFT) for Behavior Disordered Youth Aged 10-18: An Overview of Reviews
UR  - &lt;Go to ISI&gt;://WOS:000458201300009
VL  - 29
ER  -
TY  - JOUR
AB  - **Problem: **
A 2011 review of reviews reported small to moderate associations between physical activity (PA) and depression, anxiety and self-esteem among children and youth (aged 5-17 years). Due to the increase in reviews examining PA and mental health outcomes in children and youth over the past decade, we conducted an umbrella review to determine the current state of the literature, including whether effects were moderated by dose and type of PA, age, sex, or severity of mental illness. 

**Method(s):**
We systematically reviewed literature published from 2010 onwards from six online databases to identify and summarize findings from systematic reviews examining PA and depression, anxiety, and self-esteem outcomes in children and youth. We assessed review quality using the AMSTAR 2 critical appraisal tool. 

**Result(s): **
We identified 26 reviews examining depression (n = 16), anxiety (n = 2), and self-esteem (n = 14). Half of the eligible reviews were considered to be of low or critically low quality (n = 13). PA had positive mental health outcomes for children and youth, specifically for reduction in depression/depressive symptoms and improvements in physical self-concept, a self-esteem sub-domain. Little research has examined PA and anxiety. The moderator analyses reviewed revealed stronger effects in populations with clinical diagnoses (e.g. depression) and for interventions consisting of regular, supervised, group-based aerobic exercise. 

**Conclusion(s): **
PA appears to be an effective intervention for reducing depression/depressive symptoms and improving physical self-perceptions, although additional high-quality research and moderator analyses are needed to determine what type of PA interventions may result in better mental health outcomes for children and youth. 

Copyright &copy; 2018 Elsevier Ltd
AN  - 2001435705
AU  - Dale,
AU  - L.
AU  - P.
AU  - Vanderloo,
AU  - L.
AU  - Moore,
AU  - S.
AU  - Faulkner,
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.mhpa.2018.12.001
L1  - internal-pdf://2307632326/Dale-2019-Physical activity and depression, an.pdf
PY  - 2019
TI  - Physical activity and depression, anxiety, and self-esteem in children and youth: An umbrella systematic review
UR  - http://www.elsevier.com
UR  - https://ac.els-cdn.com/S1755296618301418/1-s2.0-S1755296618301418-main.pdf?_tid=09f60248-7de6-4246-9543-8a866c97c03d&amp;acdnat=1549447285_701f77a5a8a4c45230da2bfa8a76ca78
ER  -
TY  - JOUR
AB  - Computerized continuous performance tests (CPTs) are commonly used to characterize attention in attention deficit-hyperactivity disorder (ADHD). Virtual classroom CPTs, designed to enhance ecological validity, are increasingly being utilized. Lacking is a quantitative meta-analysis of clinical comparisons of attention performance in children with ADHD using virtual classroom CPTs. The objective of the present systematic PRISMA review was to address this empirical void and compare three-dimensional (3D) virtual classroom CPTs to traditional two-dimensional (2D) CPTs. The peer-reviewed literature on comparisons of virtual classroom performance between children with ADHD and typically developing children was explored in six databases (e.g., Medline). Published studies using a virtual classroom to compare attentional performance between children with ADHD and typically developing children were included. Given the high heterogeneity with modality comparisons (i.e., computerized CPTs vs. virtual classroom CPTs for ADHD), both main comparisons included only population comparisons (i.e., control vs. ADHD) using each CPT modality. Meta-analytic findings were generally consistent with previous meta-analyses of computerized CPTs regarding the commonly used omission, commission, and hit reaction time variables. Results suggest that the virtual classroom CPTs reliably differentiate attention performance in persons with ADHD. Ecological validity implications are discussed pertaining to subtle meta-analytic outcome differences compared to computerized 2D CPTs. Further, due to an inability to conduct moderator analyses, it remains unclear if modality differences are due to other factors. Suggestions for future research using the virtual classroom CPTs are provided.
AD  - Parsons, Thomas D. Computational Neuropsychology and Simulation (CNS) Laboratory, University of North Texas, 3940 N. Elm, G150, Denton, TX, 76207, USA. Thomas.Parsons@unt.edu.Parsons, Thomas D. NetDragon Digital Research Center, University of North Texas, 3940 N. Elm, G150, Denton, TX, 76207, USA. Thomas.Parsons@unt.edu.Parsons, Thomas D. Learning Technologies, College of Information, University of North Texas, 3940 N. Elm, G150, Denton, TX, 76207, USA. Thomas.Parsons@unt.edu.Duffield, Tyler. Oregon Health and Science University, Portland, OR, USA.Asbee, Justin. Computational Neuropsychology and Simulation (CNS) Laboratory, University of North Texas, 3940 N. Elm, G150, Denton, TX, 76207, USA.
AN  - 31161465
AU  - Parsons,
AU  - T.
AU  - D.
AU  - Duffield,
AU  - T.
AU  - Asbee,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s11065-019-09407-6
DP  - Ovid Technologies
J2  - Neuropsychol Rev
KW  - *Attention Deficit Disorder with Hyperactivity/di [Diagnosis]
KW  - Attention Deficit Disorder with Hyperactivity/px [Psychology]
KW  - Humans
KW  - *Neuropsychological Tests
KW  - Reaction Time
KW  - *Virtual Reality
L1  - internal-pdf://2024727588/Parsons-2019.pdf
LA  - English
M3  - Meta-AnalysisSystematic Review
N1  - Parsons, Thomas DDuffield, TylerAsbee, Justin
PY  - 2019
SP  - 338-356
T2  - Neuropsychology Review
TI  - A Comparison of Virtual Reality Classroom Continuous Performance Tests to Traditional Continuous Performance Tests in Delineating ADHD: a Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=31161465
UR  - https://link.springer.com/article/10.1007%2Fs11065-019-09407-6
UR  - https://link.springer.com/content/pdf/10.1007/s11065-019-09407-6.pdf
VL  - 29
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Autism spectrum disorder (ASD) is a neurodevelopment disorder without definitive cure. Previous studies have provided evidences for efficacy and safety of scalp acupuncture in children with ASD. However, the efficacy of scalp acupuncture treatment (SAT) in children with ASD has not been evaluated systematically. The objective of this study is to evaluate the efficacy of SAT in children with ASD. 

**METHODS: **
Information from 6 databases, including MEDLINE, EMBASE, Cochrane database, AMED, China National Knowledge Infrastructure, and Wanfang Data, were retrieved from the inception of each database from 1980 through September 2018. Randomized controlled trials evaluating the efficacy of SAT for patients with ASD were included. The primary outcome measures were the Childhood Autism Rating Scale (CARS) and Autism Behavior Checklist (ABC). The secondary outcome measures were Psychoeducational Profile (Third Edition) (PEP-3) scores. Risk of bias assessment and data synthesis were conducted with Review Manager 5.3 software. Methodological quality was assessed with the Cochrane risk of bias tool. 

**RESULTS: **
Fourteen trials with 968 participants were conducted and 11 of the trials were suitable for meta-analysis. Compared with behavioral and educational interventions, SAT significantly decreased the overall CARS scores for children under 3 years old (mean difference (MD) = 3.08, 95% confidence interval (CI) [-3.96, -2.19], P &lt; .001) and above 3 years old (MD = 5.29, 95% CI [-8.53, -2.06], P &lt; .001), ABC scores (MD = 4.70, 95% CI [-6.94, -2.79], P &lt; .001). Furthermore, SAT significantly improved PEP-3 scores in communication (MD = 3.61, 95% CI [2.85, 4.37], P &lt; .001), physical ability (MD = 2.00, 95% CI [1.16, 2.84], P &lt; .001), and behavior (MD = 2.76, 95% CI [1.80, 2.71], P &lt; .001). 

**CONCLUSION: **
SAT may be an effective treatment for children with ASD. Given the heterogeneity and number of participants, randomized controlled trials of high quality and design are required before widespread application of this therapy.
AN  - 30921186
AU  - Liu,
AU  - C.
AU  - Li,
AU  - T.
AU  - Wang,
AU  - Z.
AU  - Zhou,
AU  - R.
AU  - Zhuang,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/MD.0000000000014880
L1  - internal-pdf://1015793648/Liu-2019-Scalp acupuncture treatment for child.pdf
PY  - 2019
SP  - e14880
T2  - Medicine
TI  - Scalp acupuncture treatment for children&#039;s autism spectrum disorders: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30921186
VL  - 98
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Network meta-analyses (NMAs) are gaining traction as the preferred method for evidence synthesis of intervention studies. This review aimed to summarize the basics of NMAs and conduct a meta-review of available NMAs on the treatment of child and adolescent psychiatric disorders by appraising their quality. 

**METHOD: **
PubMed (Medline), PsycInfo, Embase, Ovid Medline, and Web of Knowledge were systematically searched (last update January 9, 2018). The quality of each included NMA was appraised using the AMSTAR-2 tool and the PRISMA-NMA checklist, which includes specific items for NMAs. 

**RESULTS: **
Eighteen NMAs (6 on attention-deficit/hyperactivity disorder; 4 on psychotic disorders; 2 on depression; 2 on anxiety disorders; 1 on obsessive-compulsive disorder; 1 on disruptive behavior disorder, 1 on bipolar disorder, and 1 on antipsychotics across disorders) were retrieved. Results from the AMSTAR-2 assessment showed that only 27% of appraised NMAs were rated as moderate quality; most were rated as low (33%) or critically low (40%) quality. Only 3 of the appraised NMAs reported on all PRISMA-NMA items specific for NMAs; the network structure was graphically presented in most NMAs (80%), and inconsistency was described in only 47%. 

**CONCLUSION: **
Given the paucity of head-to-head trials in child and adolescent psychiatry, NMAs have the potential to contribute to the field, because they provide evidence-based hierarchies for treatment decision making, even in the absence of trials directly comparing at least 2 treatments. However, because of important limitations in the included NMAs, additional methodologically sound NMAs are needed to inform future guidelines and clinical practice in child and adolescent psychiatry.
AN  - 30738544
AU  - Cortese,
AU  - S.
AU  - Tomlinson,
AU  - A.
AU  - Cipriani,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.jaac.2018.07.891
L1  - internal-pdf://1547442137/Cortese-2019-Meta-Review_ Network Meta-Analyse.pdf
PY  - 2019
SP  - 167-179
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Meta-Review: Network Meta-Analyses in Child and Adolescent Psychiatry
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30738544
UR  - https://ac.els-cdn.com/S0890856718318793/1-s2.0-S0890856718318793-main.pdf?_tid=f21d9fdf-052f-4272-83cd-358d6b90930d&amp;acdnat=1551877587_1f78944057b94aac2db722b9166083d1
VL  - 58
ER  -
TY  - JOUR
AB  - **Background**
Children&#039;s exposure to IPV is a significant public health and social justice concern. The consequences of exposure can be severe and long‐lasting. Documentation of the immense magnitude and burden of children&#039;s exposure to IPV has been met with an increased interest in the development of intervention strategies to protect this vulnerable population and promote well‐being. Over the last two decades, theory‐driven psychosocial programs serving children exposed to violence have been developed and established in other venues (e.g., school‐based mental health clinics, outpatient psychotherapy settings). This review provides a synthesis of the state of this burgeoning literature and recommendations for research. Specifically, we examined the impact of psychosocial interventions on well‐being among children exposed to IPV. Outcomes examined include overall child behavior, externalizing problems, internalizing problems. Also examined are intervention modality (e.g., individual, family‐based) and setting of the intervention (e.g., home, outpatient clinic).

**Objectives**
The objective of this review was to synthesize the evidence on the impact of psychosocial interventions on well‐being among children exposed to IPV.

**Search methods**
A combination of 10 databases and websites were searched. In addition to searching electronic resources, reference lists of relevant reviews (systematic and unsystematic) were scanned. Searches were executed by two reviewers and conducted between January and April 2018.Selection criteriaExperimental and quasiexperimental designs (with a comparison group) were eligible for inclusion. Included studies must have received a rating of low or moderate on a standardized risk of bias assessment. Additionally, studies must have examined child‐level outcomes (here defined as &gt;75% of the sample between ages 0 and 17 years), regardless of the intervention target (e.g., child and/or parent). All child‐level outcomes were of interest; that is, specific outcomes were not used as criteria for inclusion in the review.

**Data collection and analysis**
Our search identified 1,049 unique titles, all of which underwent abstract screening. Of these, 200 titles were retrieved for closer analysis of the full‐text based on the information included in the title and abstract. Subsequently, 169 full‐text reports were excluded that did not meet inclusion criteria leaving 31 articles for which we completed a risk of bias assessment. Finally, 16 articles (across 11 independent studies) studies were excluded due to coder assessed high risk of bias. This left 15 publications across eight independent studies in our final sample.All included publications underwent systematic coding of study features. To examine the impact of interventions, all child‐level outcomes were converted into standardized effect sizes reflecting the direction and magnitude of intervention effects. If we found two or more similar studies for a comparison of interest, we conducted a meta‐analysis, under a random‐effect model, of the data from those studies. We report the impact of interventions using standardized differences of means, 95% confidence intervals (CIs), and respective forest plots. Subgroup analysis was conducted to examine the impact of characteristics (modality, setting) of interest. We assessed publication bias by constructing a funnel plot to display the precision versus effect sizes of each included study.

**Results**
We identified eight RCTs, with a total of 924 participants, reporting results on the impact of a range of interventions on well‐being among children exposed to IPV. Studies examined outcomes in the following domains: total problems, externalizing distress, internalizing distress, interpersonal/social problems, and cognitive functioning. However, the clinical and methodological heterogeneity of included studies largely precluded pooling of trials. Specifically, there was a high degree of heterogeneity with regard to differences in outcomes examined, interventions employed, and comparators (some studies employed a control group whereas others were comparative effectiveness studies that examined two active interventions).Meta‐analysis was only able to be conducted for one outcome, externalizing behaviors. Meta‐analysis of two studies suggests there is preliminary evidence that in‐home intensive services (parent training and provision of emotional support to the parent) decreases child externalizing behavior among children who have been exposed to IPV and have clinical levels of behavior problems. However, support for this evidence was only found immediately posttreatment and at an 8‐month follow‐up, but not at a 4‐month follow‐up.With regard to modality, pooled findings indicate that studies targeting the nonoffending parent (mother) had the highest pooled effect size, followed by those that targeted the family together and, finally, the single study that targeted parent and child, separately. With regard to setting, pooled findings indicated that studies conducted in the home had a larger pooled effect size as compared to those conducted in an outpatient setting. However, these findings should be interpreted with great caution due to the heterogeneity in study characteristics such as the nature of the comparators.All findings taken together, it is largely unclear the extent to which psychosocial interventions promote well‐being among children exposed to IPV, and under what circumstances.

**Authors&rsquo; conclusions**
The findings from this systematic review indicate that it is largely unclear the extent to which psychosocial interventions promote well‐being among children exposed to IPV, and under what circumstances. Given the inconclusive findings from our review, below we outline three general conclusions and recommendations for future research to build the evidence base. First, the evidence base remains underdeveloped and characterized by some breadth at the sake of depth. This breath became evident during our full‐text review and systematic application of inclusion and exclusion criteria. For example, 23 reports provided a program description or presented qualitative data only, and another 37 evaluated programs but failed to include a comparison group. This suggests there is great interest in developing, describing, and evaluating programs for children exposed to IPV. In addition, 20 reports were excluded because they did not present child‐level outcomes. Studies excluded for this reason typically examined outcomes at the level of the victimized parent. The addition of child‐level measures to parent‐focused evaluations would be a contribution to the evidence base and with relatively minimal resources. Finally, we found very few replication studies&mdash;our meta‐analyses of externalizing outcomes were in fact limited to a single replication study conducted by the same team as the original study. Paired with the fact that half of the studies in our review had fewer than 100 total participants, well‐powered replication studies conducted by independent research teams will undoubtedly help move the field forward.Second, although 19 independent studies met our full‐text review inclusion criteria, 11 of these studies were ultimately excluded due to high risk of bias. Again, this highlights the breadth of programming, but unfortunately, lack of internal validity of a large proportion of existing work. We recommend&mdash;particularly for programs with strong theoretical grounding and uptake in the field (e.g., Kids&rsquo; Club, Pre Kids&rsquo; Club and Mom&#039;s Empowerment Program [MEP])&mdash;more rigorous evaluation by independent research teams.Third, consistent with the larger literature, included studies generally failed to acknowledge the varied ways in which children come to know about their parent&#039;s IPV victimization (exposure) or consider the full range of the types of IPV to which children can be exposed. Future research should consider assessing the full range of ways in which children are exposed (direct involvement, direct eyewitness, indirect exposure) to multiple types of IPV (physical, sexual, and psychological aggression, and stalking).
AU  - Latzman,
AU  - N.;
AU  - Casanueva,
AU  - C.;
AU  - Brinton,
AU  - J.;
AU  - &amp;
AU  - Forman‐Hoffman,
AU  - V.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/cl2.1049
PY  - 2019
T2  - Campbell Systematic Reviews
TI  - The promotion of well‐being among children exposed tointimate partner violence: A systematic review ofinterventions
ER  -
TY  - JOUR
AB  - This review aimed to examine the effectiveness of mental health training programs designed to improve the knowledge, attitudes, or helping behaviour of secondary school teachers for adolescent depression, anxiety, and related mental health problems. A systematic search strategy was conducted using electronic databases and hand search procedures. Eight studies met inclusion criteria, representing six unique training programs. All eight studies reported an improvement in mental health knowledge (d = 0.57-3.1) and attitudes (d = 0.36-1.18) at post-intervention. There was little evidence that the included training programs improved teachers&#039; helping behaviour or students&#039; mental health. There was no evidence to suggest that these training programs alleviated mental health problems among teachers themselves. Only two studies were conducted as randomised controlled trials. The findings suggest there may be value in providing mental health training to teachers; however, there is an urgent need for more rigorous research to determine which, if any, programs can alter teacher behaviour or improve student outcomes for mental health.
AD  - [Anderson, Melissa; Werner-Seidler, Aliza; King, Catherine; Harvey, Samuel B.; O&#039;Dea, Bridianne] Black Dog Inst, Randwick, NSW 2031, Australia. [Gayed, Aimee; Harvey, Samuel B.] Univ New South Wales, Sch Psychiat, Sydney, NSW, Australia.Anderson, M (reprint author), Black Dog Inst, Randwick, NSW 2031, Australia.melissa.anderson@blackdog.org.au
AN  - WOS:000480555400009
AU  - Anderson,
AU  - M.
AU  - Werner-Seidler,
AU  - A.
AU  - King,
AU  - C.
AU  - Gayed,
AU  - A.
AU  - Harvey,
AU  - S.
AU  - B.
AU  - O&#039;Dea,
AU  - B.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s12310-018-9291-2
J2  - School Ment. Health
KW  - Adolescence
KW  - Anxiety
KW  - Depression
KW  - Teacher
KW  - Training
KW  - Systematic review
KW  - disorders
KW  - intervention
KW  - comorbidity
KW  - knowledge
KW  - attitudes
KW  - education
KW  - literacy
KW  - children
KW  - students
KW  - behavior
KW  - Psychology
L1  - internal-pdf://1812872239/Anderson-2019.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: IQ2CATimes Cited: 1Cited Reference Count: 49Anderson, Melissa Werner-Seidler, Aliza King, Catherine Gayed, Aimee Harvey, Samuel B. O&#039;Dea, BridianneBlack Dog Institute Kickstart Seed FundingThis research was supported by a grant from the Black Dog Institute Kickstart Seed Funding.10SpringerNew york1866-2633
PY  - 2019
SP  - 489-508
T2  - School Mental Health
TI  - Mental Health Training Programs for Secondary School Teachers: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000480555400009
UR  - https://link.springer.com/article/10.1007%2Fs12310-018-9291-2
VL  - 11
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Antipsychotic drugs might cause acutely occurring, serious side-effects and thus contribute to the increased physical morbidity and mortality observed in patients with severe mental health disorders. We examined this hypothesis by doing a meta-analysis of International Conference on Harmonisation-Good Clinical Practice-defined serious adverse events occurring in placebo-controlled trials of antipsychotics. 

**METHODS:** 
For this systematic review and meta-analysis, we included randomised controlled trials (RCTs) comparing second-generation antipsychotics with placebo. We searched MEDLINE, Embase, Cochrane CENTRAL, BIOSIS, PsycINFO, PubMed, ClinicalTrials.gov, and WHO International Clinical Trials Registry Platform for trials published in any language from database inception up until Jan 27, 2017. Trials were included without limitations in population (diagnostic category, age, sex, ethnicity), dosing regimen, blinding status, duration, or publication year. Only psychological studies lasting less than 1 day and trials done in mainland China were excluded. We contacted pharmaceutical companies, drug regulatory authorities, and study investigators for additional data. The primary outcome was the number of patients with at least one somatic serious adverse event. We estimated minimum and maximum numbers of patients with the outcome in each study group and synthesised the results with odds ratios (ORs) in a common-effects meta-analysis. This study is registered with PROSPERO, number CRD42016033930. 

**FINDINGS:** 
We identified 597 RCTs, comprising 108 664 participants, that met the inclusion criteria. 314 trials (67 642 participants) with details on individual serious adverse events available constituted the main dataset for meta-analysis. 88% of these were 13 weeks (approximately 3 months) or shorter in duration (median 6 weeks, IQR 4-9). At least one somatic serious adverse event occurred in 698 (1.63%) to 862 (2.02%) of 42 600 patients on antipsychotics, and in 343 (1.37%) to 419 (1.67%) of 25 042 patients on placebo. The odds ratios (ORs) were 1.24 (95% CI 1.08-1.42) and 1.24 (1.10-1.41) based on the minimum and maximum estimate, respectively. In predefined subgroup analyses we found evidence suggesting a larger effect in older patients (&gt;65 years; OR 1.56, 95% CI 1.22-1.98; 1.58, 1.25-1.99) as compared with adults (18-65 years; 1.09, 0.91-1.29; 1.10, 0.95-1.28); likewise in children or adolescents (&lt;18 years) although the evidence was more uncertain (1.49, 0.81-2.75; 1.54, 0.85-2.77). Of 597 included RCTs, 30 (5%), 358 (60%), and 209 (35%) were rated at high, moderate, or low risk of bias, respectively. tau&lt;sup&gt;2&lt;/sup&gt; was zero for both analyses of the primary outcome (minimum estimate, maximum estimate). A Bayesian sensitivity analysis using external information on heterogeneity gave similar results. 

**INTERPRETATION:** 
We found evidence that antipsychotics cause short-term somatic serious adverse events on top of somatic serious adverse events occurring independent of treatment. This effect appears to be mainly driven by results in older patients. Hence, clinicians should be aware that antipsychotics are potentially toxic, particularly when treating patients sharing risk factors with the older population.

** FUNDING:** 
German Ministry of Education and Research.
AN  - 31320283
AU  - Schneider-Thoma,
AU  - J.
AU  - Efthimiou,
AU  - O.
AU  - Bighelli,
AU  - I.
AU  - Dorries,
AU  - C.
AU  - Huhn,
AU  - M.
AU  - Krause,
AU  - M.
AU  - Reichelt,
AU  - L.
AU  - Roder,
AU  - H.
AU  - Furukawa,
AU  - T.
AU  - A.
AU  - Davis,
AU  - J.
AU  - M.
AU  - Leucht,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/S2215-0366(19)30223-8
L1  - internal-pdf://3034311961/Schneider-Thoma-2019.pdf
PY  - 2019
SP  - 15
TI  - Second-generation antipsychotic drugs and short-term somatic serious adverse events: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31320283
UR  - https://www.sciencedirect.com/science/article/abs/pii/S2215036619302238?via%3Dihub
VL  - 15
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) frequently co-occurs with intellectual disability in children, and may further compromise learning. Methylphenidate is a first-line treatment for ADHD, however no previous meta-analysis has evaluated its overall efficacy for ADHD in children with comorbid intellectual disability (ID) or borderline intellectual functioning.The PubMed/MEDLINE, Cochrane CENTRAL and ScienceDirect databases were systematically searched from inception through 2018/7/15 for clinical studies that investigated the effects of methylphenidate in children with ADHD and ID. A random-effects model meta-analysis was used for data synthesis. Eight studies (average Jadad score = 2.5) enrolling 242 participants receiving methylphenidate and 181 participants receiving placebo were included. The meta-analysis showed that methylphenidate led to a significant improvement in ADHD symptoms relative to placebo (Hedges&#039; g = 0.878, p &lt; 0.001). Meta-regression analysis pointed to an association between the dose of methylphenidate and overall improvement in ADHD severity (slope = 1.334, p &lt; 0.001). Finally, there was no significant difference in drop-out rate [odds ratio (OR) = 1.679, p = 0.260] or rate of treatment discontinuation due to adverse events (OR = 4.815, p = 0.053) between subjects receiving methylphenidate and those taking placebos. Our study suggests that methylphenidate retains its efficacy in children with ADHD and borderline intellectual functioning or ID.
AN  - WOS:000493898100016
AU  - Sun,
AU  - C.
AU  - K.
AU  - Tseng,
AU  - P.
AU  - T.
AU  - Wu,
AU  - C.
AU  - K.
AU  - Li,
AU  - D.
AU  - J.
AU  - Chen,
AU  - T.
AU  - Y.
AU  - Stubbs,
AU  - B.
AU  - Carvalho,
AU  - A.
AU  - F.
AU  - Chen,
AU  - Y.
AU  - W.
AU  - Lin,
AU  - P.
AU  - Y.
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Wu,
AU  - M.
AU  - K.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1038/s41598-019-52205-6
L1  - internal-pdf://3759101882/Sun-2019-Therapeutic effects of methylphenidat.pdf
N1  - Sun, Cheuk-Kwan Tseng, Ping-Tao Wu, Ching-Kuan Li, Dian-Jeng Chen, Tien-Yu Stubbs, Brendon Carvalho, Andre F. Chen, Yen-Wen Lin, Pao-Yen Cheng, Yu-Shian Wu, Ming-KungSun, Cheuk-Kwan/0000-0002-2524-9684; Li, Dian-Jeng/0000-0002-6036-045X
PY  - 2019
T2  - Scientific Reports
TI  - Therapeutic effects of methylphenidate for attention-deficit/hyperactivity disorder in children with borderline intellectual functioning or intellectual disability: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000493898100016
UR  - https://www.nature.com/articles/s41598-019-52205-6.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Mass media campaigns can be used to communicate public health messages at the population level. Although previous research has shown that they can influence health behaviours in some contexts, there have been few attempts to synthesise evidence across multiple health behaviours. 

**OBJECTIVES: **
To (1) review evidence on the effective use of mass media in six health topic areas (alcohol, diet, illicit drugs, physical activity, sexual and reproductive health and tobacco), (2) examine whether or not effectiveness varies with different target populations, (3) identify characteristics of mass media campaigns associated with effectiveness and (4) identify key research gaps. 

**DESIGN: **
The study comprised (1) a systematic review of reviews, (2) a review of primary studies examining alcohol mass media campaigns, (3) a review of cost-effectiveness evidence and (4) a review of recent primary studies of mass media campaigns conducted in the UK. A logic model was developed to inform the reviews. Public engagement activities were conducted with policy, practitioner and academic stakeholders and with young people. 

**RESULTS: **
The amount and strength of evidence varies across the six topics, and there was little evidence regarding diet campaigns. There was moderate evidence that mass media campaigns can reduce sedentary behaviour and influence sexual health-related behaviours and treatment-seeking behaviours (e.g. use of smoking quitlines and sexual health services). The impact on tobacco use and physical activity was mixed, there was limited evidence of impact on alcohol use and there was no impact on illicit drug behaviours. Mass media campaigns were found to increase knowledge and awareness across several topics, and to influence intentions regarding physical activity and smoking. Tobacco and illicit drug campaigns appeared to be more effective for young people and children but there was no or inconsistent evidence regarding effectiveness by sex, ethnicity or socioeconomic status. There was moderate evidence that tobacco mass media campaigns are cost-effective, but there was weak or limited evidence in other topic areas. Although there was limited evidence on characteristics associated with effectiveness, longer or greater intensity campaigns were found to be more effective, and messages were important, with positive and negative messages and social norms messages affecting smoking behaviour. The evidence suggested that targeting messages to target audiences can be effective. There was little evidence regarding the role that theory or media channels may play in campaign effectiveness, and also limited evidence on new media. 

**LIMITATIONS: **
Statistical synthesis was not possible owing to considerable heterogeneity across reviews and studies. The focus on review-level evidence limited our ability to examine intervention characteristics in detail. 

**CONCLUSIONS: **
Overall, the evidence is mixed but suggests that (1) campaigns can reduce sedentary behaviour, improve sexual health and contribute to smoking cessation, (2) tobacco control campaigns can be cost-effective, (3) longer and more intensive campaigns are likely to be more effective and (4) message design and targeting campaigns to particular population groups can be effective. 

**FUTURE WORK: **
Future work could fill evidence gaps regarding diet mass media campaigns and new-media campaigns, examine cost-effectiveness in areas other than tobacco and explore the specific contribution of mass media campaigns to multicomponent interventions and how local, regional and national campaigns can work together. 

**STUDY REGISTRATION: **
This study is registered as PROSPERO CRD42015029205 and PROSPERO CRD42017054999. 

**FUNDING: **
The National Institute for Health Research Public Health Research programme.
AN  - 31046212
AU  - Stead,
AU  - M.
AU  - Angus,
AU  - K.
AU  - Langley,
AU  - T.
AU  - Katikireddi,
AU  - S.
AU  - V.
AU  - Hinds,
AU  - K.
AU  - Hilton,
AU  - S.
AU  - Lewis,
AU  - S.
AU  - Thomas,
AU  - J.
AU  - Campbell,
AU  - M.
AU  - Young,
AU  - B.
AU  - Bauld,
AU  - L.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3310/phr07080
L1  - internal-pdf://0057151642/Stead-2019.pdf
PY  - 2019
SP  - 4
TI  - Mass media to communicate public health messages in six health topic areas: a systematic review and other reviews of the evidence
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31046212
VL  - 4
ER  -
TY  - JOUR
AB  - **Objectives** 
Despite the relationship between physical activity (PA) and learning outcomes, the school system has not been able to support the inclusion of PA throughout the day. A solution to this problem integrates PA into the academic classroom. The objective of this review is to determine the impact of active classrooms compared to traditional sedentary classrooms on educational outcomes of school-aged children. 

**Design** 
We searched ERIC, PubMed, PsychINFO, and Web of Science, reference lists of included studies for randomised controlled studies. Independent reviewers screened the texts of potentially eligible studies and assessed the risk of bias. Data were pooled using random-effects models on standardized mean differences. 

**Results** 
This review identified 25 studies examining educational outcomes, including approximately 6,181 students. Risk of bias was assessed as either some or high risk of bias for most of the studies and outcomes. Pooled data from 20 studies and 842 participants measuring academic performance shows a small positive effect of active classrooms compared with traditional, sedentary classrooms (SMD = 0.28, 95% CI: 0.09 to 0.47). 

**Conclusions** 
Physically active classrooms may slightly improve academic achievement compared to the traditional sedentary lessons. Future research is needed to ensure that studies are adequately powered, employ appropriate methods of randomization, and measure a wide range of important student outcomes across the full spectrum of the school-age. Copyright &copy; 2019 Public Library of Science. All rights reserved.
AD  - (Bedard) Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada (Bedard, Bremer, Graham) INfant and Child Health (INCH) Lab, Department of Family Medicine, Master University, Hamilton, ON, Canada (St John, Cairney) INfant and Child Health (INCH) Lab, Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada (Bremer) Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, CanadaC. Bedard, Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada. E-mail: bedardct@mcmaster.ca
AN  - 2002358362
AU  - Bedard,
AU  - C.
AU  - St
AU  - John,
AU  - L.
AU  - Bremer,
AU  - E.
AU  - Graham,
AU  - J.
AU  - D.
AU  - Cairney,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0218633
DP  - Ovid Technologies
KW  - academic achievement
KW  - adult
KW  - article
KW  - female
KW  - human
KW  - human experiment
KW  - male
KW  - Medline
KW  - meta analysis
KW  - outcome assessment
KW  - PsycINFO
KW  - randomization
KW  - randomized controlled trial (topic)
KW  - risk assessment
KW  - student
KW  - systematic review
KW  - Web of Science
L1  - internal-pdf://4288233120/Bedard-2019-A systematic review and meta-analy.pdf
LA  - English
PY  - 2019
T2  - PLoS ONE
TI  - A systematic review and meta-analysis on the effects of physically active classrooms on educational and enjoyment outcomes in school age children
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0218633&amp;type=printable
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2002358362
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:31237913&amp;id=doi:10.1371%2Fjournal.pone.0218633&amp;issn=1932-6203&amp;isbn=&amp;volume=14&amp;issue=6&amp;spage=e0218633&amp;pages=&amp;date=2019&amp;title=PLoS+ONE&amp;atitle=A+systematic+review+and+meta-analysis+on+the+effects+of+physically+active+classrooms+on+educational+and+enjoyment+outcomes+in+school+age+children&amp;aulast=Bedard&amp;pid=%3Cauthor%3EBedard+C.%3C%2Fauthor%3E%3CAN%3E2002358362%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
VL  - 14 (6) (no pagination)
ER  -
TY  - JOUR
AB  - **Purpose:** 
This systematic review summarizes and critically appraises the existing literature on brief interventions (BIs) for cannabis use among emerging adults. 

**Method(s):** 
Eligible BIs were operationalized as 1-2 sessions focused exclusively on cannabis use for samples with mean ages between 15 and 30. Outcomes related to cannabis use, other substance use, mental health, help-seeking, or functional status were included. Two independent reviewers screened a total of 3638 records, identifying 244 studies for full-text screening. In total, 32 BIs in 26 primary studies with 6318 participants were included. 

**Result(s):** 
Participants were typically not seeking treatment and using cannabis at least once a month. Most interventions were motivational, single sessions, and delivered in person. Few discussed concurrent psychiatric conditions. Pooling results at 1-3 months post-intervention, BIs compared to passive control slightly reduced symptoms of cannabis use disorder (SMD -0.14 [95% CI -0.26 to -0.01]) and increased the odds of abstinence (OR 1.73 [95% CI 1.13-2.66]). Other outcome results often favored BIs but were not significant. Results of studies comparing types of BIs (k = 8) or BIs to longer interventions (k = 1) are discussed narratively. Quality assessment suggested low to very low-quality evidence. 

**Conclusion(s):** 
This review indicates that BIs targeting non-treatment seeking emerging adults result in significant reductions in symptoms of cannabis use disorder and an increased likelihood of cannabis abstinence, however evidence is of low quality. Copyright &copy; 2019 Elsevier B.V.
AD  - (Halladay, Linton, Munn) Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4S4, Canada (Scherer, MacKillop, Petker) Peter Boris Centre for Addictions Research, McMaster University/St, Joseph&#039;s Healthcare Hamilton, 100 West 5th St, Hamilton, Ontario L8N 3K7, Canada (MacKillop, Munn) Michael G. DeGroote Centre for Medicinal Cannabis Research, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4S4, Canada (MacKillop, Munn) Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4S4, Canada (Woock) Department of Health, Aging, and Society, 1280 Main Street West, Hamilton, Ontario L8S 4S4, CanadaJ. Halladay, Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4S4, Canada. E-mail: halladje@mcmaster.ca
AN  - 2003839757
AU  - Halladay,
AU  - J.
AU  - Scherer,
AU  - J.
AU  - MacKillop,
AU  - J.
AU  - Woock,
AU  - R.
AU  - Petker,
AU  - T.
AU  - Linton,
AU  - V.
AU  - Munn,
AU  - C.
DA  - 1 November
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.drugalcdep.2019.107565
DP  - Ovid Technologies
KW  - Adolescent
KW  - Brief intervention
KW  - Cannabis
KW  - Emerging adult
KW  - Motivational
KW  - Young adult
KW  - abstinence
KW  - adult
KW  - article
KW  - cannabis addiction
KW  - cannabis use
KW  - controlled study
KW  - female
KW  - functional status
KW  - human
KW  - male
KW  - mental health
KW  - meta analysis
KW  - quality control
KW  - systematic review
L1  - internal-pdf://1827294663/Halladay-2019-Brief interventions for cannabis.pdf
LA  - English
PY  - 2019
T2  - Drug and Alcohol Dependence
TI  - Brief interventions for cannabis use in emerging adults: A systematic review, meta-analysis, and evidence map
UR  - http://www.elsevier.com/locate/drugalcdep
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2003839757
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.drugalcdep.2019.107565&amp;issn=0376-8716&amp;isbn=&amp;volume=204&amp;issue=&amp;spage=107565&amp;pages=&amp;date=2019&amp;title=Drug+and+Alcohol+Dependence&amp;atitle=Brief+interventions+for+cannabis+use+in+emerging+adults%3A+A+systematic+review%2C+meta-analysis%2C+and+evidence+map&amp;aulast=Halladay&amp;pid=%3Cauthor%3EHalladay+J.%3C%2Fauthor%3E%3CAN%3E2003839757%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/271276/1-s2.0-S0376871619X00101/1-s2.0-S0376871619303424/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEND%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJHMEUCICzDF8Ja2bY78EQybn7ciGYpDsCbnDEGej1DJD%2F7NDZ4AiEAycgzXnxEyI3%2FeRO72eAIM3WQ2vSPy6IOPi2j98guN9Uq0AIIKBACGgwwNTkwMDM1NDY4NjUiDP91%2FdWqapfiEdcpqiqtAtCMzvddXMpr%2BbZz4MTE0xJuvyNHB60VCWFJJKnmMW54FRJLEi%2B9OLPozNSX769ol7BaEfwAfo2MdLnX0JzpLcjOsgyWpPgmBy5NialqhjDoxUkeFEzh3Q0yzsEQG9CZLYj8%2BEdro7wZB%2BGV8LXc4N57XQ0i0fXBdubCrGHhKjXcFiCrNxfDJHCj%2F3nVTcMo1%2FLe%2FKWQLAw8TziwyZAJ33ftTLu5ZD5Iz3vP6Zaw73vFNFJWR0JTJpXcWVS8JW%2FAGEW7SPQVb%2FAuiAsMVdtQUSfJbjCiKCCEQ6FPtnPv8tbod6lW4Cs0n0XH3vBy2O2cA%2FbPwn%2B3xDCO4TKSFdsTtmfLj%2BiNrskVXno%2FHVTN7gjlYIWD9MvsbIg8wa5yqDvg45fKH9H0qEJJlX0tJ6ww5PXM7wU6zwJUKkKc6aSlYMYFMKRfftQINUXWnAob6fLSf6OFAuIsptF6%2BQhIX1K9gG2OatRHihNqTWnRhjj6DYe9BlLz7xPCjqIkoVHnyoNmSdiizkN4o1%2BjMMP1%2Bqm5D6iewMM%2F%2F51UfhVbDUKaEKnsrJDT1xkhcYvS6VMT4%2FpRCiRM4p7Ac8YHq7uyWW7Zps15sQgJsF5qErHmx8x4NtqQoC17L2rQNc5oM5Z%2FO5vvUzQloFPZYJ4W4fT%2Bq78mnU%2BRYxtUvIMWyxamYzEs4Z5EQVbFij04je0eADlZwC8ZLwJEJgCXIC0d5ySKn4dumXsdtSULYWA5CRrMA7q516ZkYoNiQzoqqIBCJbZJIMvfv%2FC4OlFprQXne8HXZM9NbtPBeejJPhGIePQzjYZvt1hru77lHAiAJiRv1%2FPpRxXb7ofYGOLl%2FKze1MQxxK%2FXzbJVK9xNvQ%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20191213T090029Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY7P4CYCKD%2F20191213%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=194ca06d360ca3c06d35474bcc530a87a1884dd776adf48ee4cd90b99360c19e&amp;hash=24e4db721d0161ed453477f668606d07aa6bb315308d31d9ac2f4d5ddfb415bc&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0376871619303424&amp;tid=spdf-a98f9c81-4bcf-4c19-b4e2-1a6864f8df55&amp;sid=1c47b7374b651743b25aa4713ec30aabc77cgxrqb&amp;type=client
VL  - 204 (no pagination)
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To evaluate the efficacy and tolerability of pharmacotherapy in pediatric anxiety disorders using network meta-analysis. 

**DATA SOURCES: **
PubMed, Cochrane Database, Web of Science, PsycNET, and ClinicalTrials.gov were searched for double-blind, controlled pharmacotherapy trials in youth with anxiety disorders from 1966 to September 2017. 

**DATA SELECTION:**
All double-blind, placebo-controlled trials of pharmacotherapy in the treatment of pediatric patients with generalized, social, and/or separation anxiety disorders were included. 

**DATA EXTRACTION: **
We extracted demographic, symptom severity, global improvement, discontinuation, and suicidality data. Risk of bias was assessed with the Cochrane risk-of-bias tool, and a network meta-analysis comparing the efficacy and tolerability of medications and medication classes was performed using the gemtc package (R). 

**RESULTS:** 
We identified 20 citations (22 RCTs, 24 treatment arms) with 2,623 patients. Selective serotonin reuptake inhibitors (SSRIs) were the only class that was superior in reducing anxiety (standardized mean difference: 5.2; credible interval [CrI]: [2.8 to 8.8]) and in likelihood of treatment response compared to placebo (odds ratio [OR]: 4.6; CrI: [3.1 to 7.5]). Serotonin-norepinephrine reuptake inhibitor (SNRI) and alpha2 agonist treatment were associated with more frequent treatment response compared to placebo. The likelihood of treatment response was greater for SSRIs compared to SNRIs (OR: 1.9; CrI: [1.1 to 3.5]). All-cause discontinuation and treatment-emergent suicidality significantly differed among medications but not medication class. 

**CONCLUSIONS: **
Although multiple medications reduce anxiety in children and adolescents, treatment response, tolerability, and treatment-emergent suicidality differ among these medications and medication classes. Determining whether efficacy and tolerability differences represent true differences (or reflect differences in trial design) requires additional head-to-head medication trials and-to exclude the impact of missing treatment interventions-requires trials of medications that successfully treat anxiety in adults but that have not been evaluated in youth.
AN  - 30753760
AU  - Dobson,
AU  - E.
AU  - T.
AU  - Bloch,
AU  - M.
AU  - H.
AU  - Strawn,
AU  - J.
AU  - R.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.4088/JCP.17r12064
L1  - internal-pdf://1650792659/Dobson-2019-Efficacy and Tolerability of Pharm.pdf
PY  - 2019
SP  - 29
T2  - Journal of Clinical Psychiatry
TI  - Efficacy and Tolerability of Pharmacotherapy for Pediatric Anxiety Disorders: A Network Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30753760
UR  - https://www.psychiatrist.com/JCP/article/Pages/2019/v80/17r12064.aspx
VL  - 80
ER  -
TY  - JOUR
AB  - INTRODUCTION: 
This study aimed to evaluate the efficacy of pharmacotherapy for smoking cessation among adolescent smokers by using a meta-analysis of randomized controlled trials (RCTs).

METHODS: 
PubMed, EMBASE, and Cochrane Library were searched from the inception to January 20, 2018. We included RCTs of pharmacotherapy for smoking cessation among adolescent smokers aged less than 20 years. Data were pooled using a random-effects meta-analysis. The primary outcome measures were a smoking abstinence rate and its relative risk (RR) at the longest follow-up period in each study validated by biochemical markers.

RESULTS: 
Among a total of 1035 articles searched, nine RCTs, which involved 1188 adolescent smokers aged 12-20 years with 627 in the intervention group and 561 in the control group, were included in the final analysis. In the random-effects meta-analysis of all the nine trials, pharmacotherapy showed a increased abstinence rate (RR = 1.62; 95% confidence interval [CI] = 1.08 to 2.44, I2 = 0.0%), compared with the control group. Subgroup meta-analyses by follow-up period showed an increased abstinence rate at 4 weeks (RR = 1.87; 95% CI = 1.22 to 2.87; n = 4) and a nonsignificantly increased abstinence rate during the longer term follow-up periods at 8, 12, 24, and 52 weeks.

CONCLUSIONS: 
The current meta-analysis suggests that pharmacotherapy can be considered as an aid for smoking cessation in the short-term period among adolescent smokers. However, further large RCTs are warranted to determine its long-term efficacy and safety.

IMPLICATIONS:
In this meta-analysis of nine RCTs with 1188 adolescent smokers aged 12-20 years, pharmacotherapy showed an increased abstinence rate, compared with the control group. In the subgroup meta-analyses by follow-up period, it showed the increased abstinence rate at 4 weeks and no efficacy on abstinence during the longer term follow-up periods up to 52 weeks. Further large RCTs are warranted to determine the long-term efficacy and safety of pharmacotherapy in adolescent smokers.
AD  - Myung, Seung-Kwon. Department of Cancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, Goyang, Republic of Korea.Myung, Seung-Kwon. Cancer Epidemiology Branch, Division of Cancer Epidemiology and Prevention, Research Institute, National Cancer Center, Goyang, Republic of Korea.Myung, Seung-Kwon. Department of Family Medicine and Center for Cancer Prevention and Detection, National Cancer Center Hospital, Goyang, Republic of Korea.Park, Joo-Young. Seoul Science High School, Seoul, Republic of Korea.
AN  - 30165705
AU  - Myung,
AU  - S.
AU  - K.
AU  - Park,
AU  - J.
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1093/ntr/nty180
DP  - Ovid Technologies
J2  - Nicotine Tob Res
KW  - Adolescent
KW  - Adolescent Behavior
KW  - Adolescent Health Services
KW  - Child
KW  - Humans
KW  - Randomized Controlled Trials as Topic
KW  - *Smoking Cessation
KW  - *Tobacco Use Cessation Devices
KW  - *Tobacco Use Disorder/dt [Drug Therapy]
KW  - Young Adult
L1  - internal-pdf://3797187501/Myung-2019.pdf
LA  - English
M3  - Meta-Analysis
N1  - Myung, Seung-KwonPark, Joo-Young
PY  - 2019
SP  - 1473-1479
T2  - Nicotine &amp; Tobacco Research
TI  - Efficacy of Pharmacotherapy for Smoking Cessation in Adolescent Smokers: A Meta-analysis of Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=30165705
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30165705&amp;id=doi:10.1093%2Fntr%2Fnty180&amp;issn=1462-2203&amp;isbn=&amp;volume=21&amp;issue=11&amp;spage=1473&amp;pages=1473-1479&amp;date=2019&amp;title=Nicotine+%26+Tobacco+Research&amp;atitle=Efficacy+of+Pharmacotherapy+for+Smoking+Cessation+in+Adolescent+Smokers%3A+A+Meta-analysis+of+Randomized+Controlled+Trials.&amp;aulast=Myung&amp;pid=%3Cauthor%3EMyung+SK%3C%2Fauthor%3E%3CAN%3E30165705%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://academic.oup.com/ntr/article-abstract/21/11/1473/5085260?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/nty180.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAoIwggJ-BgkqhkiG9w0BBwagggJvMIICawIBADCCAmQGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMTNap48jGI364FkTvAgEQgIICNeuH-utyxMjcSVPEKBnKJa6GrmOLYML_F1O6qg5nh5t7PHgL86hNq1uhkmor4NhSmO7jj9pB-WV_JKZBVv7Qu7ZvOcUqgKTrwDBGa8LNyTHDVP78OZCG6MsDJZyZrKXvfvBDof2QV2Yg6bJhdTyjVVOtIM13vN3DSdooeSQZBFKV7qUZFCQeSDMdlQ7FPgL-bGz0zRf4useNHzmmCr0qpsAiSfU0teznlrdP92Wk1JoudWy6xNwWIrYO5Ybglvxx2v6j6PDXlz8-tssgW2ACZiRgNqqCwJEbTF8v2bEiUKtlRMaIdC943HC8inUKYgJXvdn1lTXhMrJI2WVNDnc6qw-G_LMWuI7zaguf_xoNxTjrJB9fxsNnwQOu_va26yLw1DvajwF_j0w22QUNk5aaYz9hxKhkC68H6jh-vXmDfDFOdZo2aPymivBnV6y63SefaxM0QTBnSrYgNThiA9rNcxgZqGLN_KZEwEJODWh1kDvwFbDQYDCcYnvhxevRay9Q-z_aIDnUg0Czr9RKXa2Dve0Me9xsmVyy8PkncbM6XwBZhNxWBZNARNMSMbL3cC7RLMiN-Cmu-o0uLA0ynDMSWMf-HRV6Q-aHmXdkUat4q0JBqU5rcnTjf1ulHlTLZAxvkSGksRpVMi-t11gQeW-TyTa-G985dse4Rdl8lVsFxtmL4VYX0-9ywqBawVDs4uJO4hwz3bkR831PisamJhSA4AMKILXrbmuxYR3rHky3wrxfpoGjvfo
VL  - 21
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Autism spectrum disorders (ASD) are a set of neurodevelopmental disorders characterised by behavioural, communication and social impairments. The prevalence of sleep disturbances in children with ASD is 40-80%, with significant effects on quality of life for the children and carers. This systematic review aimed to synthesise evidence of the effects of behavioural interventions to improve sleep among children with ASD.

**METHODS:** 
Databases (MEDLINE, PsycINFO, CINAHL, ScienceDirect, Autism Data, CENTRAL, ClinicalTrials.gov and Current Controlled Trials) were searched for published, unpublished and ongoing randomised controlled trials evaluating the effect of non-pharmacological interventions for insomnia in children with autism spectrum conditions.

**RESULTS:** 
Three studies met the inclusion criteria, one provided actigraphy data, one Children&#039;s Sleep Habits Questionnaire (CSHQ) data, and one both actigraphy and CSHQ data for use in meta-analyses. There were significant differences between the behavioural intervention and comparison groups (actigraphy data) for total sleep time (24.41 minutes, 95% CI 5.71, 43.11, P = 0.01), sleep latency (-18.31 minutes, 95% CI -30.84, -5.77, P = 0.004) and sleep efficiency (5.59%, 95% CI 0.87, 10.31, P = 0.02). There was also a favourable intervention effect evident for the subjective CSHQ data (-4.71, 95% CI -6.70, -2.73, P&lt;0.00001). Risk of bias was low across several key domains (randomisation, allocation concealment and reporting), with some studies being unclear due to poor reporting.

**CONCLUSIONS:** 
There are very few high quality randomised controlled trials in this area. Here we provide initial synthesised quantitative evidence of the effectiveness of behavioural interventions for treating sleep problems in children with ASD.

**TRIAL REGISTRATION:** 
Protocol was registered (CRD42017081784) on the International Prospective Register of Systematic Reviews (http://www.crd.york.ac.uk/PROSPERO).
AD  - Keogh, Sophie. Lincolnshire Partnership Foundation Trust, Lincoln, United Kingdom.Bridle, Christopher. Lincoln Institute for Health, University of Lincoln, Lincoln, United Kingdom.Siriwardena, Niroshan A. Lincoln Institute for Health, University of Lincoln, Lincoln, United Kingdom.Nadkarni, Amulya. Lincolnshire Partnership Foundation Trust, Lincoln, United Kingdom.Laparidou, Despina. Lincoln Institute for Health, University of Lincoln, Lincoln, United Kingdom.Durrant, Simon J. Lincoln Institute for Health, University of Lincoln, Lincoln, United Kingdom.Kargas, Niko. Lincoln Institute for Health, University of Lincoln, Lincoln, United Kingdom.Law, Graham R. Lincoln Institute for Health, University of Lincoln, Lincoln, United Kingdom.Curtis, Ffion. Lincoln Institute for Health, University of Lincoln, Lincoln, United Kingdom.
AN  - 31437211
AU  - Keogh,
AU  - S.
AU  - Bridle,
AU  - C.
AU  - Siriwardena,
AU  - N.
AU  - A.
AU  - Nadkarni,
AU  - A.
AU  - Laparidou,
AU  - D.
AU  - Durrant,
AU  - S.
AU  - J.
AU  - Kargas,
AU  - N.
AU  - Law,
AU  - G.
AU  - R.
AU  - Curtis,
AU  - F.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1371/journal.pone.0221428
DP  - Ovid Technologies
J2  - PLoS ONE
L1  - internal-pdf://0200730879/Keogh-2019-Effectiveness of non-pharmacologica.pdf
LA  - English
N1  - Keogh, SophieBridle, ChristopherSiriwardena, Niroshan ANadkarni, AmulyaLaparidou, DespinaDurrant, Simon JKargas, NikoLaw, Graham RCurtis, Ffion
PY  - 2019
SP  - e0221428
T2  - PLoS ONE [Electronic Resource]
TI  - Effectiveness of non-pharmacological interventions for insomnia in children with Autism Spectrum Disorder: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31437211
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31437211&amp;id=doi:10.1371%2Fjournal.pone.0221428&amp;issn=1932-6203&amp;isbn=&amp;volume=14&amp;issue=8&amp;spage=e0221428&amp;pages=e0221428&amp;date=2019&amp;title=PLoS+ONE+%5BElectronic+Resource%5D&amp;atitle=Effectiveness+of+non-pharmacological+interventions+for+insomnia+in+children+with+Autism+Spectrum+Disorder%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Keogh&amp;pid=%3Cauthor%3EKeogh+S%3C%2Fauthor%3E%3CAN%3E31437211%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705823/pdf/pone.0221428.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - **Background**
Comorbid depression and substance use disorders are common and have poorer outcomes than either disorder alone. While effective psychological treatments for depression or substance use disorders are available, relatively few randomised controlled trials (RCTs) have examined the efficacy of these treatments in people with these comorbid disorders.

**Objectives**
To assess the efficacy of psychological interventions delivered alone or in combination with pharmacotherapy for people diagnosed with comorbid depression and substance use disorders.

**Search methods**
We searched the following databases up to February 2019: Cochrane Central Register of Controlled Trials, PubMed, Embase, CINAHL, Google Scholar and clinical trials registers. All systematic reviews identified, were handsearched for relevant articles.

**Selection criteria**
The review includes data from RCTs of psychological treatments for people diagnosed with comorbid depression and substance use disorders, using structured clinical interviews. Studies were included if some of the sample were experiencing another mental health disorder (e.g. anxiety); however, studies which required a third disorder as part of their inclusion criteria were not included. Studies were included if psychological interventions (with or without pharmacotherapy) were compared with no treatment, delayed treatment, treatment as usual or other psychological treatments.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane.Main resultsSeven RCTs of psychological treatments with a total of 608 participants met inclusion criteria. All studies were published in the USA and predominately consisted of Caucasian samples. All studies compared different types of psychological treatments. Two studies compared Integrated Cognitive Behavioural Therapy (ICBT) with Twelve Step Facilitation (TSF), another two studies compared Interpersonal Psychotherapy for Depression (IPT‐D) with other treatment (Brief Supportive Therapy (BST) or Psychoeducation). The other three studies compared different types or combinations of psychological treatments. No studies compared psychological interventions with no treatment or treatment as usual control conditions. The studies included a diverse range of participants (e.g. veterans, prisoners, community adults and adolescents).All studies were at high risk of performance bias, other main sources were selection, outcome detection and attrition bias. Due to heterogeneity between studies only two meta‐analyses were conducted. The first meta‐analysis focused on two studies (296 participants) comparing ICBT to TSF. Very low‐quality evidence revealed that while the TSF group had lower depression scores than the ICBT group at post‐treatment (mean difference (MD) 4.05, 95% confidence interval (CI) 1.43 to 6.66; 212 participants), there was no difference between groups in depression symptoms (MD 1.53, 95% CI ‐1.73 to 4.79; 181 participants) at six‐ to 12‐month follow‐up. At post‐treatment there was no difference between groups in proportion of days abstinent (MD ‐2.84, 95% CI ‐8.04 to 2.35; 220 participants), however, the ICBT group had a greater proportion of days abstinent than the TSF group at the six‐ to 12‐month follow‐up (MD 10.76, 95% CI 3.10 to 18.42; 189 participants). There were no differences between the groups in treatment attendance (MD ‐1.27, 95% CI ‐6.10 to 3.56; 270 participants) or treatment retention (RR 0.95, 95% CI 0.72 to 1.25; 296 participants).The second meta‐analysis was conducted with two studies (64 participants) comparing IPT‐D with other treatment (Brief Supportive Psychotherapy/Psychoeducation). Very low‐quality evidence indicated IPT‐D resulted in significantly lower depressive symptoms at post‐treatment (MD ‐0.54, 95% CI ‐1.04 to ‐0.04; 64 participants), but this effect was not maintained at three‐month follow‐up (MD 3.80, 95% CI ‐3.83 to 11.43) in the one study reporting follow‐up outcomes (38 participants; IPT‐D versus Psychoeducation). Substance use was examined separately in each study, due to heterogeneity in outcomes. Both studies found very low‐quality evidence of no significant differences in substance use outcomes at post‐treatment (percentage of days abstinent, IPD versus Brief Supportive Psychotherapy; MD ‐2.70, 95% CI ‐28.74 to 23.34; 26 participants) or at three‐month follow‐up (relative risk of relapse, IPT‐D versus Psychoeducation; RR 0.67, 95% CI 0.30 to 1.50; 38 participants). There was also very low‐quality evidence for no significant differences between groups in treatment retention (RR 1.00, 95% CI 0.81 to 1.23; 64 participants). No adverse events were reported in any study.

**Authors&#039; conclusions**
The conclusions of this review are limited due to the low number and very poor quality of included studies. No conclusions can be made about the efficacy of psychological interventions (delivered alone or in combination with pharmacotherapy) for the treatment of comorbid depression and substance use disorders, as they are yet to be compared with no treatment or treatment as usual in this population. In terms of differences between psychotherapies, although some significant effects were found, the effects were too inconsistent and small, and the evidence of too poor quality, to be of relevance to practice.
AU  - Hides,
AU  - L.
AU  - Quinn,
AU  - C.
AU  - Stoyanov,
AU  - S.
AU  - Kavanagh,
AU  - D.
AU  - Baker,
AU  - A.
DA  - 26. Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.CD009501.pub2
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological interventions for co‐occurring depression and substance use disorders
ER  -
TY  - JOUR
AB  - Bullying is an international phenomenon that is increasingly becoming recognized as a public health issue and mental health concern. 

Systematic reviews suggest that complex, whole-school anti-bullying interventions are effective at reducing victimization and bullying in high-income countries (HICs). We report a systematic review evaluating the effectiveness of school-based interventions to reduce and prevent bullying among adolescents in low- and middle-income countries (LMICs). 

In addition to searching 31 databases, we also hand searched key journals and grey literature. We contacted experts in the field for input during the search process. After rigorously screening retrieved studies against predetermined inclusion/exclusion criteria, only three studies were included in this review. 

One study used a cognitive and behavioral approach to target bullying among adolescents in Romania, one study adapted the international Olweus Bullying Prevention Program (OBPP) for use in Malaysia, and the other developed a model for use in South Africa. Results from all three studies were mixed and provided no overall evidence of effect for the interventions. 

The validity of the results for two of the studies was unclear due to substantial or unclear risks of bias. Given the well-established evidence base for anti-bullying interventions in HICs, there is an urgent need for more rigorously evaluated and reported studies in LMICs, adapted for contexts of considerable resource constraints. 

Copyright &copy; 2018 Elsevier Ltd
AN  - 2000973568
AU  - Sivaraman,
AU  - B.
AU  - Nye,
AU  - E.
AU  - Bowes,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.avb.2018.07.007
L1  - internal-pdf://1068692404/Sivaraman-2019-School-based anti-bullying inte.pdf
PY  - 2019
SP  - 154-162
T2  - Aggression and Violent Behavior
TI  - School-based anti-bullying interventions for adolescents in low- and middle-income countries: A systematic review
UR  - http://www.elsevier.com/locate/aggviobeh
UR  - https://www.sciencedirect.com/science/article/pii/S1359178918301150?via%3Dihub
VL  - 45
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
The operation areas of clowns in the medical context are multifaceted. Clowning in children undergoing surgery has been shown to be able to lessen children&#039;s anxiety. Hence, our aim was to assess the effectiveness of clowning on anxiety in children undergoing potentially anxiety-provoking procedures.

**METHODS:** 
We searched MEDLINE, CENTRAL, and EMBASE for randomized controlled trials (RCTs) in December 2018. The primary outcome was children&#039;s anxiety. We used the Cochrane risk of bias tool to assess risk of bias of the included studies.

**RESULTS:** 
We found eleven RCTs including 733 children. Their risk of bias was relatively high. Children undergoing clowning were significantly less anxious in preoperative time compared to parental presence or no intervention (mean difference (MD) - 7.16; 95% CI - 10.58, - 3.75) and in operation, induction, or patient room (MD - 20.45; 95% CI - 35.54, - 5.37), but not during mask application or physician examination (MD 2.33; 95% CI - 4.82, 9.48). Compared with midazolam, children&#039;s anxiety was significantly lower in preoperative time (MD - 7.60; 95% CI - 11.73, - 3.47), but not in the induction room (MD - 9.63; 95% CI - 21.04, 1.77).

**CONCLUSIONS:** 
Clowning seems to lower children&#039;s anxiety, but because of the increased risk of bias of included studies and the very low quality of evidence, these results should be considered with caution. Systematic review registration: Prospero crd42016039045.
AD  - Konsgen, Nadja. Institute of Health Economics and Clinical Epidemiology, University of Cologne, Gleueler Strase 176-178, 50935, Cologne, Germany.Polus, Stephanie. Institute for Research in Operative Medicine, Witten/Herdecke University, Ostmerheimer Str. 200, 51109, Cologne, Germany.Rombey, Tanja. Institute for Research in Operative Medicine, Witten/Herdecke University, Ostmerheimer Str. 200, 51109, Cologne, Germany.Pieper, Dawid. Institute for Research in Operative Medicine, Witten/Herdecke University, Ostmerheimer Str. 200, 51109, Cologne, Germany. dawid.pieper@uni-wh.de.
AN  - 31324215
AU  - Konsgen,
AU  - N.
AU  - Polus,
AU  - S.
AU  - Rombey,
AU  - T.
AU  - Pieper,
AU  - D.
DA  - Jul 19
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s13643-019-1095-4
DP  - Ovid Technologies
J2  - Syst
L1  - internal-pdf://0030294945/Konsgen-2019-Clowning in children undergoing p.pdf
LA  - English
N1  - Konsgen, NadjaPolus, StephanieRombey, TanjaPieper, Dawid
PY  - 2019
SP  - 178
T2  - Systematic Reviews
TI  - Clowning in children undergoing potentially anxiety-provoking procedures: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31324215
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31324215&amp;id=doi:10.1186%2Fs13643-019-1095-4&amp;issn=2046-4053&amp;isbn=&amp;volume=8&amp;issue=1&amp;spage=178&amp;pages=178&amp;date=2019&amp;title=Systematic+Reviews&amp;atitle=Clowning+in+children+undergoing+potentially+anxiety-provoking+procedures%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Konsgen&amp;pid=%3Cauthor%3EKonsgen+N%3C%2Fauthor%3E%3CAN%3E31324215%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642518/pdf/13643_2019_Article_1095.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **Background:** 
Systematic reviews and meta-analyses (reviews) conflict regarding the efficacy and feasibility of substance disorder treatments for young people (YP). This overview of reviews, synthesizes, and methodologically assesses reviews examining substance disorder interventions for YP in outpatient settings. 

**Method(s):** 
Reviews published between 1990 and March 2018 were searched using EBM Reviews, PsycINFO, Embase, Ovid Medline, and Campbell Collaboration. Reviews investigating efficacy and/or feasibility of YP substance disorder treatments in outpatient settings were included. Forty-three reviews met all inclusion criteria: To appraise methodological biases, 40 reviews were assessed using A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR2) and 3 were narratively assessed. One reviewer (NS) extracted study data and evaluated all 43 reviews. For inter-rater reliability, 13 (30%) reviews were extracted and appraised in duplicate by a second reviewer (JA, RC or ES). Agreement on AMSTAR2 ratings reached 100%. Agreement was moderate; kappa = .52 (p &lt; .05), 95% CI (.20, .84). 

**Result(s):** 
All high quality methodological reviews (n = 6) focused on intervention efficacy and none on treatment feasibility. One (n = 1) high quality review reported evidence for an intervention. Multidimensional Family Therapy (MDFT) has possible efficacy in reducing YP substance use when compared to treatment as usual, Cognitive Behavior Therapy, Adolescent Community Reinforcement Approach and Multifamily Educational Therapy. 

**Conclusion(s):** 
Methodological and reporting quality of reviews require improvement. High quality reviews focused on intervention efficacy but treatments commonly lacked evidence. One high quality review found MDFT demonstrated promising outcomes. Reviews examining feasibility of interventions were of low methodological quality. Copyright &copy; 2019 Elsevier B.V.
AD  - (Snowdon, Allan) Lives Lived Well Research Team, Lives Lived Well, P.O. Box 9374, Orange, NSW 2800, Australia (Snowdon, Shakeshaft, Stockings, Boland, Courtney) National Drug and Alcohol Research Centre, The University of New South Wales, 22 - 32 King Street, Randwick, Sydney, NSW 2031, Australia (Rickwood) Research and Evaluation, headspace, The National Youth Mental Health Foundation, South Tower, Level 2, 485 La Trobe St, Melbourne, VIC 3000, Australia (Shakeshaft, Rickwood) Faculty of Health, Allawoona St, University of Canberra, Bruce, Canberra, ACT 2617, AustraliaN. Snowdon, Lives Lived Well, P.O. Box 9374, Orange, NSW 2800, Australia. E-mail: nicole.snowdon@liveslivedwell.org.au
AU  - Snowdon,
AU  - N.
AU  - Allan,
AU  - J.
AU  - Shakeshaft,
AU  - A.
AU  - Rickwood,
AU  - D.
AU  - Stockings,
AU  - E.
AU  - Boland,
AU  - V.
AU  - C.
AU  - Courtney,
AU  - R.
AU  - J.
DA  - 1 December
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1016/j.drugalcdep.2019.107582
DP  - Ovid Technologies
KW  - Adolescence
KW  - Overview of reviews
KW  - Psychosocial treatment
KW  - Substance use
KW  - A MeaSurement Tool to Assess systematic Reviews
KW  - adolescent
KW  - article
KW  - cognitive behavioral therapy
KW  - comparative effectiveness
KW  - controlled study
KW  - Embase
KW  - family therapy
KW  - feasibility study
KW  - female
KW  - human
KW  - interrater reliability
KW  - male
KW  - Medline
KW  - outpatient
KW  - PsycINFO
KW  - reinforcement
KW  - systematic review
L1  - internal-pdf://1556197720/Snowdon-2019-Outpatient psychosocial substance.pdf
LA  - English
PY  - 2019
T2  - Drug and Alcohol Dependence
TI  - Outpatient psychosocial substance use treatments for young people: An overview of reviews
UR  - http://www.elsevier.com/locate/drugalcdep
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2003939547
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:31778903&amp;id=doi:10.1016%2Fj.drugalcdep.2019.107582&amp;issn=0376-8716&amp;isbn=&amp;volume=205&amp;issue=&amp;spage=107582&amp;pages=&amp;date=2019&amp;title=Drug+and+Alcohol+Dependence&amp;atitle=Outpatient+psychosocial+substance+use+treatments+for+young+people%3A+An+overview+of+reviews&amp;aulast=Snowdon&amp;pid=%3Cauthor%3ESnowdon+N.%3C%2Fauthor%3E%3CAN%3E2003939547%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/271276/1-s2.0-S0376871619X00113/1-s2.0-S037687161930359X/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjECsaCXVzLWVhc3QtMSJHMEUCIGtE4TGXEe0i2bs8zYE7zH3TP%2FeUWYAkuNzdo2QMuGlUAiEAwigIIbfvHTDEEaVzS02lkEYRFLMQMZBoE1AsnMeZ2OIqvQMIpP%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FARACGgwwNTkwMDM1NDY4NjUiDAGlE%2FFNGVm0MJEdHyqRA%2BmmiU8aRd7F%2BoW7vUTRFxu4BW13AoQ5ddPR5tnJ71GmUNDtQJcwehBzj2IEMIiGHNKEC7j4X3tG9n9xHLj5MI%2BLUabffXkC7WGP%2FCl2FY7G6XIkaGVFKefExdh0TsgNVOu5%2Fd%2B6r3JXwEXH9hRfznXr89PpuhoJt%2BlZzdEHbEKAOtHG3XieG4qwjnmsaSBeByiYyAR50KfDBO1lkq0Z2zZKrzWQxgIs82T0ZhPAVVPSrUblzx2LUPh%2FH2TP14gECYOXjZXnH7ez1fCBGkGqK9Cf2mAwFR%2Fvy51Dzdg877O4ybYuFeg6he0Sm86fScqyQhL6ISORPgePfnFVvA3PTDgkjz1Je3Oz1b0%2F61Wz2ZdTSRHO2QeFQj5B8wOONgz5sSwVyr5fwta18wlSJYQXNmXo0AtTJdxYn%2BDGZoavjjS%2FrAg3Y85H9YnDRWjonR6swfKNyX7OjVFPMws3pd7xu3UsSWU9n1O5xNoJ4XY1rx3hBM0gMPu3qE6FQWkzT57KQwz8sPN34FDuvytB3by2YftEMIK%2F0fAFOusBOJAAcAV78cpnsxbv8E8HNy%2BFhickb5arJcRx%2FkQL7pWS0%2FrD1xLZ3m6hiN6gxVmLL2zmYlMmkB5fEr3zsqrXidxwDfJ8e7S23eql7b1W%2FG0Yncge7KvgsQLchNOn%2B6DKxxKI5LyYniGHk1uLx3yRXeHgEzwd3aminqrHZmBaPeCW6aMYw64dIdBC51x%2FMH0wsukXOtO4zy%2Bipwpfd2iBDCb7eyu7YN4gkh1gbhQr4BCzr7fg48FqaONZ8%2BcCCN29%2F5sk%2BaF6kAzRMq3aqCC%2FpkB1Bv%2B0XgRTfptXLYg9mSx913wPpoRmSsHjrw%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20200107T120513Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY2ZWFZGOS%2F20200107%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=5126b81d1c55e61d57ecf63f336ae46dfbfeec398b0d9f799b038a422feed2f2&amp;hash=5448876ef4ec621d34c3b5515226df3ed2b52343a0ea04d7ef306e05793e4877&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S037687161930359X&amp;tid=spdf-5aa7dab9-03ad-4071-83c1-d8cc31959e00&amp;sid=61b92c0668433147e41997289189dccd6622gxrqb&amp;type=client
VL  - 205 (no pagination)
ER  -
TY  - JOUR
AB  - Despite the prevalence and negative consequences of depressive disorders among youth, as well as the need for schools to adopt and implement a continuum of mental health services to address depressive disorders, school mental health providers receive very limited guidance in the selection and application of appropriate evidence-based depression prevention and intervention programs for use within a school-based multi-tiered system of support (MTSS). 

With the goal of supporting school-based mental health providers in the delivery of evidence-based practices targeting depressive symptoms among youth within a MTSS framework, the following study sought to conduct a critical review of the existing school-based prevention and intervention programming for depressive disorders for youth. 

A systematic, four-stage review was performed from which 119 studies examining 57 unique programs were identified. A review of the studies, including presentation of various participant (e.g., age, grade, ethnicity), study (e.g., control group, randomization), and program (e.g., primary focus, findings, MTSS tier) characteristics, is included. Implementation considerations review and future directions for research are discussed.
AN  - WOS:000468099900005
AU  - Arora,
AU  - P.
AU  - G.
AU  - Collins,
AU  - T.
AU  - A.
AU  - Dart,
AU  - E.
AU  - H.
AU  - Hernandez,
AU  - S.
AU  - Fetterman,
AU  - H.
AU  - Doll,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s12310-019-09314-4
L1  - internal-pdf://1482460204/Arora-2019-Multi-tiered Systems of Support for.pdf
PY  - 2019
SP  - 240-264
T2  - School Mental Health
TI  - Multi-tiered Systems of Support for School-Based Mental Health: A Systematic Review of Depression Interventions
UR  - &lt;Go to ISI&gt;://WOS:000468099900005
UR  - https://link.springer.com/article/10.1007%2Fs12310-019-09314-4
VL  - 11
ER  -
TY  - JOUR
AB  - Can Internet‐based interventions help people to stop smoking? 

Background

Tobacco use is estimated to kill 7 million people a year. Nicotine is highly addictive, but surveys indicate that almost 70% of US and UK smokers would like to stop smoking. Although many smokers attempt to give up on their own, advice from a health professional increases the chances of quitting. As of 2016 there were 3.5 billion Internet users worldwide. The Internet is an attractive platform to help people quit smoking because of low costs per user, and it has potential to reach smokers who might not access support because of limited health care availability or stigmatisation. Internet‐based interventions could also be used to target young people who smoke, or others who may not seek traditional methods of smoking treatment.

Study Characteristics

Up to August 2016, this review found 67 trials, including data from over 110,000 participants. Smoking cessation data after six months or more were available for 35,969 participants. We examined a range of Internet interventions, from a low intensity intervention, for example providing participants with a list of websites for smoking cessation, to intensive interventions consisting of Internet‐, email‐ and mobile phone‐delivered components. We classed interventions as tailored or interactive, or both. Tailored Internet interventions differed in the amount of tailoring, from multimedia components to personalised message sources. Some interventions also included Internet‐based counselling or support from nurses, peer coaches or tobacco treatment specialists. Recent trials incorporated online social networks, such as Facebook, Twitter, and other online forums.

Key results

In combined results, Internet programmes that were interactive and tailored to individual responses led to higher quit rates than usual care or written self‐help at six months or longer.

Quality of evidence

There were not many trials conducted in younger people. More trials are needed to determine the effect on Internet‐based methods to aid quitting in youth and young adults. Results should be interpreted with caution, as we rated some of the included studies at high risk of bias, and for most outcomes the quality of evidence was moderate or low.

Authors&#039; conclusions
Implications for practice
Evidence in adults suggests that interactive and tailored Internet‐based interventions may be slightly more effective than usual care or printed self‐help at six months or longer. However these results should be interpreted with caution, as we judged some of the studies to be at high risk of bias, and there was evidence of substantial statistical heterogeneity. In adults there was evidence that tailored and interactive interventions delivered with additional behavioural support were more effective than non‐active controls, but with evidence of substantial statistical heterogeneity. We found no evidence that Internet interventions with or without the addition of behavioural support were better than active smoking cessation treatments. There were only 10 studies of Internet interventions in adolescents or young adults and only four of these were eligible for meta‐analysis, so treatment effectiveness in younger smokers is unknown.

Implications for research
There remains a requirement for higher‐quality studies, adequately powered and reporting bioverified smoking cessation, with at least six months follow‐up. In this review there were only 10 studies conducted in adolescents or young adults, and only four of these were suitable for meta‐analysis. More trials of Internet interventions aimed at younger smokers (i.e. 25 years and younger) are needed to determine the effectiveness of Internet interventions for this group. Most studies were conducted in high‐income countries, which leaves a knowledge gap about the effectiveness of Internet interventions in developing countries.
AN  - CD007078
AU  - Taylor,
AU  - G.
AU  - Dalili,
AU  - M.
AU  - Semwal,
AU  - M.
AU  - Civljak,
AU  - M.
AU  - Sheikh,
AU  - A.
AU  - Car,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007078.pub4
KW  - Internet
KW  - Program Evaluation
KW  - Randomized Controlled Trials as Topic
KW  - Smoking Cessation [methods]
KW  - Therapy, Computer-Assisted [methods]
KW  - Treatment Outcome
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Tobacco
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Internet-based interventions for smoking cessation
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007078.pub4/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007078.pub4/asset/CD007078.pdf?v=1&amp;t=iw7jt8t8&amp;s=f93486bbe520e07c47f3202f3e8516ec3f8f5ec0
ER  -
TY  - JOUR
AB  - **Objective:** 
A systematic review and meta-analysis of randomized controlled trials (RCTs) were conducted to assess the benefits and harms of vitamin D supplementation for attention-deficit/hyperactivity disorder (ADHD) patients. 

**Methods:** 
We followed the standard methodological procedures of the Cochrane Handbook for Systematic Reviews of Intervention. PubMed, Embase, the Cochrane Central Register of Controlled Trials, Science and Conference Proceedings Citation Index-Social Science and Humanities (Web of Science), ClincalTrials.gov, and World Health Organization&#039;s International Clinical Trials Registry Platform were searched for RCTs in January 2019. Independently, two authors (J.G., T.X.) extracted data, assessed the risk of bias, combined the data, and graded evidence quality using the Grading of Recommendations Assessment, Development, and Evaluation approach. Our primary outcomes were assessed through rating scales of ADHD severity. Secondary outcomes measured were the possible adverse effects of vitamin D supplementation and vitamin D status after supplementation for ADHD. 

**Results:** 
We included four RCTs with 256 children addressing vitamin D supplementation as adjunctive therapy to methylphenidate on ADHD symptoms. Vitamin D supplementation demonstrated a small but statistically significant improvement in ADHD total scores, inattention scores, hyperactivity scores, and behavior scores. The improvement was likely limited due to the low to very low quality of evidence in the literature. There was no statistically significant improvement in oppositional scores. Reported adverse events in the vitamin D group were mild and not significantly different from the control group. Vitamin D supplementation increased serum vitamin D levels and the ratio of patients with sufficient vitamin D levels. 

**Conclusions:** 
Vitamin D supplementation as adjunctive therapy to methylphenidate appeared to reduce ADHD symptoms without serious adverse events, associated with improved vitamin D status. However, considering the generally low strength of evidence, well-designed RCTs are needed to determine the efficacy and safety of vitamin D supplementation for both children and adults with ADHD, especially in the setting of a combination of vitamin D and other ADHD treatments.
AD  - Gan, Jing. 1Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.Gan, Jing. 2Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.Galer, Peter. 3Department of Biomedical and Health Informatics (DBHI), The Children&#039;s Hospital of Philadelphia, Philadelphia, Pennsylvania.Ma, Dan. 1Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.Chen, Chao. 1Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.Chen, Chao. 2Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.Xiong, Tao. 1Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.Xiong, Tao. 2Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.Xiong, Tao. 4Deep Underground Space Medical Center, West China Hospital, Sichuan University, Chengdu, China.
AN  - 31368773
AU  - Gan,
AU  - J.
AU  - Galer,
AU  - P.
AU  - Ma,
AU  - D.
AU  - Chen,
AU  - C.
AU  - Xiong,
AU  - T.
DA  - Aug 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/cap.2019.0059
DP  - Ovid Technologies
J2  - J Child Adolesc Psychopharmacol
L1  - internal-pdf://4087628236/Gan-2019.pdf
LA  - English
N1  - Using Smart Source ParsingAugGan, JingGaler, PeterMa, DanChen, ChaoXiong, Tao
PY  - 2019
SP  - 01
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - The Effect of Vitamin D Supplementation on Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31368773
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31368773&amp;id=doi:10.1089%2Fcap.2019.0059&amp;issn=1044-5463&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2019&amp;title=Journal+of+Child+%26+Adolescent+Psychopharmacology&amp;atitle=The+Effect+of+Vitamin+D+Supplementation+on+Attention-Deficit%2FHyperactivity+Disorder%3A+A+Systematic+Review+and+Meta-Analysis+of+Randomized+Controlled+Trials.&amp;aulast=Gan&amp;pid=%3Cauthor%3EGan+J%3C%2Fauthor%3E%3CAN%3E31368773%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 01
ER  -
TY  - JOUR
AB  - Atomoxetine is prescribed to children with autism spectrum disorder having symptoms of attention deficit hyperactivity disorder. We sought to examine the efficacy and safety of atomoxetine in this population. After screening for inclusion criteria, we identified three randomized placebo controlled trials involving 241 children. 

We assessed internal validity using standard Cochrane Risk of bias tool for randomized controlled trials (RCTs). We used Revman 5.3 for meta-analysis and GRADE approach to create summary of findings with grading of the quality of evidence. Atomoxetine had a benefit on improving parent-rated hyperactivity (standardized mean difference [SMD] = -0.73, 95% Confidence Interval, CI = -1.15 to -0.34) and parent-rated inattention (SMD = -0.53, 95% CI = -0.93 to -0.12) but the magnitude of effects is uncertain. 

However, atomoxetine was also associated with increased risk of non-serious adverse effects like nausea and vomiting, decreased sleep, and decreased appetite. Atomoxetine may be effective in improving hyperactivity and inattention in children with autism spectrum disorder and attention deficit hyperactivity disorder. 

However, we are uncertain about the true effect of this intervention and need more RCTs trials designed to evaluate this. 

Autism Research 2019. &copy; 2019 International Society for Autism Research, Wiley Periodicals, Inc. 

**LAY SUMMARY: **
Atomoxetine is prescribed for Attention Deficit Hyperactivity Disorder (ADHD). About a third of children and adolescents with autism also suffer from ADHD. We carried out an analysis of data reported from a specific kind of medication trials which had examined the effectiveness and side effects of atomoxetine in this patient population. We could find only three such trials and analyzed the reported data. Our analysis revealed that atomoxetine is effective in improving symptoms of ADHD like hyperactivity and inattention and also causes side effects like nausea, vomiting, decreased sleep, and decreased appetite. However, the existing data are insufficient to provide a conclusive statement with certainty and more trials are needed for this.
AN  - 30653855
AU  - Patra,
AU  - S.
AU  - Nebhinani,
AU  - N.
AU  - Viswanathan,
AU  - A.
AU  - Kirubakaran,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/aur.2059
L1  - internal-pdf://3434525533/Patra-2019-Atomoxetine for attention deficit h.pdf
PY  - 2019
SP  - 17
T2  - Autism research : Official Journal of the International Society for Autism Research
TI  - Atomoxetine for attention deficit hyperactivity disorder in children and adolescents with autism: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30653855
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1002/aur.2059
VL  - 17
ER  -
TY  - JOUR
AB  - **Background**
Bipolar disorder is a common condition associated with high morbidity; developing efficacious, safe treatments is therefore essential. Lithium is an effective maintenance treatment for bipolar disorder. It acts as mood stabiliser and reduces the risk of suicide. However, evidence assessing the efficacy of lithium in the treatment of acute mania is less robust. Current evidence‐based guidelines cite multiple anti‐dopaminergic and mood‐stabilising agents as initial treatments: more definite evidence is needed to decide if lithium should be the first‐line therapy.

**Objectives**
1. To assess the effects of lithium in comparison with placebo or other active treatment in alleviating the acute symptoms of a manic or mixed episode in people with bipolar disorder.
2. To review the acceptability and tolerability of treatment with lithium in comparison with placebo or other active treatments in alleviating the acute symptoms of a manic or mixed episode in people with bipolar disorder.

**Search methods**
We searched the Cochrane Common Mental Disorders Controlled Trials Register, CENTRAL, MEDLINE, Embase, and PsycINFO. We also searched the World Health Organization trials portal (ICTRP) and ClinicalTrials.gov. We checked the reference lists of all included studies and relevant systematic reviews. We have incorporated studies from searches to 18 May 2018 into the current analyses.

**Selection criteria**
Prospective randomised controlled studies comparing lithium with placebo or alternative drug treatment in treatment of acute mania. We included anyone with bipolar disorder, male and female, of any age.

**Data collection and analysis**
At least two review authors independently extracted data and assessed methodological quality. We used odds ratios (ORs) to analyse binary efficacy outcomes, and mean differences (MDs) or standardised mean differences (SMDs) for continuously distributed outcomes. We used a fixed‐effect model unless heterogeneity was moderate or substantial, in which case we used a random‐effects model. We used Review Manager 5 to analyse data. We assessed the certainty of evidence for individual outcomes using the GRADE approach.

**Main results**
We found 36 randomised controlled studies comparing lithium with placebo, one of 12 drugs, or electroconvulsive therapy for treatment of acute mania. Studies included male and female participants (n = 4220), of all ages, who all fitted criteria for a manic episode within the context of a diagnosis of bipolar disorder. Risk of bias was variable; 12 studies had a high risk of bias in one domain and 27 gave inadequate information on randomisation leading to an &#039;unclear&#039; rating for selection bias.

**Lithium versus placebo**
High‐certainty evidence found that lithium was an effective treatment for acute mania and was more effective than placebo at inducing a response (OR 2.13, 95% confidence interval (CI) 1.73 to 2.63; participants = 1707; studies = 6; I2 = 16%; high‐certainty evidence), or remission (OR 2.16, 95% CI 1.73 to 2.69; participants = 1597; studies = 5; I2 = 21%; high‐certainty evidence).Lithium was more likely than placebo to cause tremor (OR 3.25, 95% CI 2.10 to 5.04; participants = 1241; studies = 6; I2 = 0%; high‐certainty evidence), and somnolence (OR 2.28, 95% CI 1.46 to 3.58; participants = 1351; studies = 7; I2 = 0%; high‐certainty evidence).There was insufficient evidence to determine the effect of lithium for all‐cause dropouts (OR 0.76; 95% CI 0.46 to 1.25; participants = 1353; studies = 7; I2 = 75%; moderate‐certainty evidence), and weight gain (OR 1.48, 95% CI 0.56 to 3.92; participants = 735, studies = 3; I2= 51%; moderate‐certainty evidence).

**Lithium versus antipsychotics or mood stabilisers** 
For the outcome of inducing a response, there was only very low‐certainty evidence regarding lithium compared to haloperidol (MD &minus;2.40, 95% CI &minus;6.31 to 1.50; participants = 80; studies = 3; I2 = 95%), quetiapine (OR 0.66, 95% CI 0.28 to 1.55; participants = 335; studies = 2; I2 = 71%), and carbamazepine (SMD 0.21, 95% CI &minus;0.18 to 0.60; participants = 102; studies = 3; I2 = 0%).Lithium was probably less likely to induce a response than olanzapine (OR 0.44, 95% CI 0.20 to 0.94; participants = 180; studies = 2; I2 = 0%; moderate‐certainty evidence).Lithium may be less likely to induce a response than risperidone (MD 7.28, 95% CI 5.22 to 9.34; participants = 241; studies = 3; I2 = 49%; low‐certainty evidence).There was no evidence of a difference between lithium and valproate (OR 1.22, 95% CI 0.87 to 1.70; participants = 607; studies = 5; I2 = 22%; moderate‐certainty evidence).There was moderate‐certainty evidence that lithium was more effective than topiramate at treating acute mania (OR 2.28, 95% CI 1.63 to 3.20; participants = 660; studies = 1).Data on adverse events for these comparisons contained too few studies to provide high‐certainty evidence.

**Authors&#039; conclusions**
This systematic review indicates that lithium is more effective than placebo as a treatment for acute mania but increases the risk for somnolence and tremor. Limited evidence suggests little or no difference between lithium and other mood stabilisers (valproate, carbamazepine) or antipsychotics (risperidone, quetiapine, haloperidol). Olanzapine may be an exception, as it is probably slightly more effective than lithium. There is uncertain evidence that risperidone may also be more effective than lithium. Lithium is probably more effective at treating acute mania than topiramate. When compared to placebo, lithium was more likely to cause adverse events. However, when compared to other drugs, too few studies provided data on adverse effects to provide high‐certainty evidence. More, rigorously designed, large‐scale studies are needed to definitively conclude if lithium is superior to other interventions in treating acute mania.
AU  - McKnight,
AU  - R.
AU  - N.
AU  - de
AU  - La
AU  - Motte
AU  - de
AU  - Bro&ouml;ns
AU  - de
AU  - Vauvert,
AU  - S.
AU  - J.
AU  - G.
AU  - N.
AU  - Chesney,
AU  - E.
AU  - Amit,
AU  - B.
AU  - H.
AU  - Geddes,
AU  - J.
AU  - Cipriani,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1002/14651858.CD004048.pub4
L1  - internal-pdf://3302934423/McKnight-2019-Lithium for acute mania.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Lithium for acute mania
ER  -
TY  - JOUR
AB  - Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder in children and is associated with significant risk of educational failure, interpersonal problems, mental illness, and delinquency. Despite a number of comparative and comprehensive reviews on the effects of ADHD treatments on ADHD core symptoms, evidence synthesizing the effects of ADHD interventions on cognitive difficulties is limited. In this meta-analysis, the neuropsychological effects of non-pharmacological interventions for ADHD were examined across studies published between 1980 and 2017. Data were extracted from studies that used objective cognitive measures (either computerized or pencil-and-paper), and multiple meta-analyses were conducted to compare the effectiveness across these interventions. Publication bias was assessed, as well as quality of the evidence, using Cochrane risk of bias tool for randomized control trials studies. Our final meta-analysis included 18 studies with interventions that were categorized into four categories: neurofeedback, cognitive-behavioral therapy, cognitive training, and physical exercises. Physical exercises demonstrated the highest average effect size (Morris d=0.93). A further evaluation of cognitive functions yielded 49 effect sizes for the five categories, including attention, inhibition, flexibility, and working memory. Analyses demonstrated a homogenous, medium to large, effect size of improvement across interventions, with inhibition demonstrating the largest average effect size (Morris d=0.685). This study highlights the positive effect of psychological interventions on ADHD cognitive symptomology and supports the inclusion of non-pharmacological interventions in conjunction with the commonly used pharmacological treatments.
AD  - Lambez, Bar. Department of Psychology, Bar Ilan University, Ramat-Gan, Israel.Harwood-Gross, Anna. Department of Psychology, Bar Ilan University, Ramat-Gan, Israel; Herman Dana Division of Child and Adolescent Psychiatry, Hadassah Hospital, Jerusalem, Israel.Golumbic, Elana Zion. Leslie and Susan Gonda (Goldschmied) Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan, Israel.Rassovsky, Yuri. Department of Psychology, Bar Ilan University, Ramat-Gan, Israel; Leslie and Susan Gonda (Goldschmied) Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan, Israel; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles (UCLA), California, USA. Electronic address: yurir@biu.ac.il.
AN  - 31629998
AU  - Lambez,
AU  - B.
AU  - Harwood-Gross,
AU  - A.
AU  - Golumbic,
AU  - E.
AU  - Z.
AU  - Rassovsky,
AU  - Y.
DA  - Oct 12
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jpsychires.2019.10.007
DP  - Ovid Technologies
J2  - J Psychiatr Res
L1  - internal-pdf://2075683638/Lambez-2019-Non-pharmacological interventions.pdf
LA  - English
M3  - Review
N1  - Lambez, BarHarwood-Gross, AnnaGolumbic, Elana ZionRassovsky, YuriS0022-3956(19)30616-8
PY  - 2019
SP  - 40-55
T2  - Journal of Psychiatric Research
TI  - Non-pharmacological interventions for cognitive difficulties in ADHD: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31629998
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31629998&amp;id=doi:10.1016%2Fj.jpsychires.2019.10.007&amp;issn=0022-3956&amp;isbn=&amp;volume=120&amp;issue=1&amp;spage=40&amp;pages=40-55&amp;date=2019&amp;title=Journal+of+Psychiatric+Research&amp;atitle=Non-pharmacological+interventions+for+cognitive+difficulties+in+ADHD%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Lambez&amp;pid=%3Cauthor%3ELambez+B%3C%2Fauthor%3E%3CAN%3E31629998%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/271251/1-s2.0-S0022395619X00114/1-s2.0-S0022395619306168/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEG4aCXVzLWVhc3QtMSJHMEUCIAW9ltTLgl5DyMpTa5JSh2sFWe97u%2FBLWYH7ZmKkZP2RAiEAt5ZwEvc0DaW976a%2F9f3Egz9NfeD%2BrAVwYIzxLwN%2FNlgq2AIIh%2F%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FARACGgwwNTkwMDM1NDY4NjUiDJCQARyhpg7Rl5syoiqsAun3c4ZPu8dpYVpuoWN%2BTL40%2FA%2FiTTjK%2F30G2GftYxfNpp7wKDBzwrFGeM5Mz5rf56M7VwVJJ1H1yAqYbc0VhKgugUZh0IUHZGcfkd33Dc74ToiyIJ4xmC0EFC38osuV3hkxPkCGoMy4uNyhdnJDI1NIRg47MRis3Vbr8UKDXwD9PmJZkUIDjoYNTRQlCxJIgRtlFF4Q4Ai%2BOzhQxXMwa7WWgJt%2FbpgzKt4233BXFIBn7yjCnQr3d6%2FA2Ahn75WFpfMqIZljx2%2BkNwpO7a%2BoGqrYNZZO8xtssE8sDvUtRcXb%2Ffc8nGXnDVtvH01RbNBU2WgmC4MEoYHibqhW9gj1scQ3S4R3jiJmmGo8Q3vS%2B7%2BE8cZ4qnIOzuwvNL5EeckIqGwK%2FyGQaoTQNdnaAzDh3Y7uBTrQArDE5Vcopq1%2Fe48b4zHGoJ2EpjnnNrDf3PJ7PKiCJJPW8O8s2W7vJzixF84Y11VQ4WcmMaWNzjI40YbxOnl4r47jOZ0X%2FhSmESgima3%2BNR9iHacGCIP9IppvydtV8dKhavQZnX442%2FdjcaUZA9Xknlr8g%2Fx%2FZDGuBWV6Qp8TGDwBAyUvB74EzERSdzZpDcTmayB5AvvmBFbcTXoWJ%2BssykA8LasjqlWJIJQYADJWwUnrWeylV%2FXCMiwhRhntODPs2F9kzk0MpqE365jm5rlGQWGpltpJl03wxMddoBvisrcg5fxjLig4qbCPeGyxDlh3lbmcO5o5f2rE47hxKQQbR%2BUNcYVMaNs9vgULyihkbgCanRn3JwzORw0I0XoQeksxDYXlq21qPA4Rh%2Fp3JAUUAMhnqbygnZe%2BDzR%2FvwkCWz%2BmPE8dYOu4vtKB9JZICbXgDA%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20191107T072812Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY5I6XXNBI%2F20191107%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=a038c012fed880f6c564e79f1849dff7038c8e1ceff0d9a8456bdf4570e2ad03&amp;hash=efdb8b8ee35740c2a883e77c32544fe853f672c88a16ce78aedda43f53ea3a44&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0022395619306168&amp;tid=spdf-839cca87-1ce7-4df5-85f0-030523ab160b&amp;sid=f8da4bf317fff741da7bb23-5fe716ca08c9gxrqb&amp;type=client
VL  - 120
ER  -
TY  - JOUR
AB  - **Background** 
Post-traumatic stress disorder (PTSD) is a potentially chronic and disabling disorder that affects a significant minority of youth exposed to trauma. Previous studies have concluded that trauma-focused cognitive behavioural therapy (TF-CBT) is an effective treatment for PTSD in youth, but the relative strengths of different psychological therapies are poorly understood. 

**Methods** 
We undertook a systematic review and network meta-analyses of psychological and psychosocial interventions for children and young people with PTSD. Outcomes included PTSD symptom change scores post-treatment and at 1-4-month follow-up, and remission post-treatment. 

**Results** 
We included 32 trials of 17 interventions and 2,260 participants. Overall, the evidence was of moderate-to-low quality. No inconsistency was detected between direct and indirect evidence. Individual forms of TF-CBT showed consistently large effects in reducing PTSD symptoms post-treatment compared with waitlist. The order of interventions by descending magnitude of effect versus waitlist was as follows: cognitive therapy for PTSD (SMD -2.94, 95%CrI -3.94 to -1.95), combined somatic/cognitive therapies, child-parent psychotherapy, combined TF-CBT/parent training, meditation, narrative exposure, exposure/prolonged exposure, play therapy, Cohen TF-CBT/cognitive processing therapy (CPT), eye movement desensitisation and reprocessing (EMDR), parent training, group TF-CBT, supportive counselling and family therapy (SMD -0.37, 95%CrI -1.60 to 0.84). Results for parent training, supportive counselling and family therapy were inconclusive. Cohen TF-CBT/CPT, group TF-CBT and supportive counselling had the largest evidence base. Results regarding changes in PTSD symptoms at follow-up and remission post-treatment were uncertain due to limited evidence. 

**Conclusions** 
Trauma-focused cognitive behavioural therapy, in particular individual forms, appears to be most effective in the management of PTSD in youth. EMDR is effective but to a lesser extent. Supportive counselling does not appear to be effective. Results suggest a large positive effect for emotional freedom technique, child-parent psychotherapy, combined TF-CBT/parent training, and meditation, but further research is needed to confirm these findings as they were based on very limited evidence.
AN  - WOS:000476366700001
AU  - Mavranezouli,
AU  - I.
AU  - Megnin-Viggars,
AU  - O.
AU  - Daly,
AU  - C.
AU  - Dias,
AU  - S.
AU  - Stockton,
AU  - S.
AU  - Meiser-Stedman,
AU  - R.
AU  - Trickey,
AU  - D.
AU  - Pilling,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jcpp.13094
L1  - internal-pdf://3892897847/Mavranezouli-Psychological and psychosocial tr.pdf
PY  - 2019
SP  - 12
T2  - Journal of Child Psychology and Psychiatry
TI  - Psychological and psychosocial treatments for children and young people with post-traumatic stress disorder: a network meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000476366700001
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcpp.13094
ER  -
TY  - JOUR
AB  - Despite the rising interest in intervention for children with autism spectrum disorder, the extent to which interventions are effective on gross motor outcomes is currently unknown. The purpose of this study was to analyze the effect of different intervention approaches on gross motor outcomes among children with autism spectrum disorder using meta-analysis. A total of 18 studies met the inclusion criteria for quantitative analysis. Pre- and posttest means and SDs were extracted to calculate effect sizes. Potential moderator variables were chosen based on important intervention characteristics. The results suggest that interventions have a large effect on gross motor outcomes among children with autism spectrum disorder (delta = 0.99, SE = 0.19, p &lt; .001, 95% confidence interval [0.62, 1.36]). The interventions that were 16 total hours or longer had a significantly larger effect than those less than 16 hr. In addition, the interventions in experimental settings had significantly larger effects than the interventions in practical settings. Future interventions should consider intensity, including not only the duration of the intervention but also the intensity in which specific intervention goals are targeted.
AD  - Case, Layne. Oregon State University.Yun, Joonkoo. Oregon State University.
AN  - 31521058
AU  - Case,
AU  - L.
AU  - Yun,
AU  - J.
DA  - Sep 13
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1123/apaq.2018-0174
DP  - Ovid Technologies
J2  - Adapt Phys Act Q
L1  - internal-pdf://4171359417/Case-2019.pdf
LA  - English
M3  - Review
N1  - Case, LayneYun, Joonkooapaq.2018-0174
PY  - 2019
SP  - 1-26
T2  - Adapted Physical Activity Quarterly
TI  - The Effect of Different Intervention Approaches on Gross Motor Outcomes of Children With Autism Spectrum Disorder: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31521058
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31521058&amp;id=doi:10.1123%2Fapaq.2018-0174&amp;issn=0736-5829&amp;isbn=&amp;volume=36&amp;issue=4&amp;spage=1&amp;pages=1-26&amp;date=2019&amp;title=Adapted+Physical+Activity+Quarterly&amp;atitle=The+Effect+of+Different+Intervention+Approaches+on+Gross+Motor+Outcomes+of+Children+With+Autism+Spectrum+Disorder%3A+A+Meta-Analysis.&amp;aulast=Case&amp;pid=%3Cauthor%3ECase+L%3C%2Fauthor%3E%3CAN%3E31521058%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.humankinetics.com/view/journals/apaq/36/4/article-p501.xml
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
Adequate nutrients early in life promote cognitive development and are critical for proper growth and functioning. The effect of individual nutrients consumed through food is often not the same as consuming the same nutrients in supplementary form due to &#039;food synergy&#039;, the biological and chemical interrelations that occur between nutrients. Animal-source foods, such as eggs, meat, fish, and dairy, are energy dense and contain multiple micronutrients and essential fatty acids with high bioavailability. The benefits of animal-source foods may include higher food synergy relative to fortified foods as well as decreasing dependence on external suppliers of fortified foods.

**OBJECTIVES:**
To assess the effectiveness of animal-source foods compared to any other feeding interventions or no intervention in improving growth and developmental outcomes in children aged 6 to 59 months.

**SEARCH METHODS:**
We searched CENTRAL, MEDLINE, Embase, CINAHL, 18 other databases, and three trials registers up to August 2018. We also contacted authors and known experts in the field for assistance in identifying ongoing or unpublished data, and searched the reference lists of included studies and reviews, and websites of relevant organizations, for other studies that may not have been captured by our electronic searches.

**SELECTION CRITERIA:**
We included randomized controlled trials and quasi-randomized controlled trials of any duration, where children between 5 months and 59 months (6 years) of age were provided with an animal-source food (e.g. consumption of milk, meat, or eggs), prepared with any cooking method, compared with any intervention or no intervention.

**DATA COLLECTION AND ANALYSIS:**
Two review authors independently assessed trial eligibility using prespecified criteria, extracted data, assessed risk of bias, and graded the quality of the evidence using the GRADE approach.

**MAIN RESULTS:**
Study characteristicsWe included 6 studies that analyzed data from 3036 children aged 5 to 50 months. The studies were conducted in China, the Democratic Republic of Congo, Ecuador, Guatemala, Pakistan, the USA, and Zambia, and lasted between 5 and 12 months. Three studies were funded, in part, by government entities; one study was supported by a nonprofit organization. Two studies did not report a funding source.Three studies compared the effects of feeding an animal-source food with a fortified (iron or iron and zinc), or unfortified cereal; two used a control group with no intervention; one compared a meat-based diet to a dairy-based diet. The types of animal-source foods tested included yogurt, eggs, cheese, lyophilized (freeze-dried) beef product, ground and frozen pork, pur&eacute;ed and jarred beef with gravy or pork, and powdered whey protein.We judged four studies to be at unclear risk of bias overall; three studies because they were funded by an industry with a plausible interest in the outcome of the intervention; and one study because there was insufficient information to assess five of the seven bias &#039;Risk of bias&#039; domains. We judged two of the six studies to be at high risk of bias overall; one study because there was significant baseline imbalance in length-for-age z scores (LAZ) between groups and evidence of selective reporting; the other study because there there was both a significant baseline imbalance in LAZ and weight-for-age z scores (WAZ) between groups, and a large-scale social media campaign that may have influenced care received at home in the control group.Key resultsAnimal-source foods versus cereal-based foods or no interventionFive studies (2972 children) measured change in linear growth with either height-for-age z scores (HAZ) or LAZ. Three studies (592 children) reported a significant increase in HAZ and LAZ in the intervention group compared to the control group. Two studies (2380 children) reported a decline in LAZ in both groups. In one study (1062 children) there was no difference between the groups in the rate of decline; in the other (1318 children) the decrease in LAZ was significantly smaller in the intervention group.Five studies (2972 children) measured weight gain using WAZ. Three studies (592 children) reported a significant increase in WAZ in the intervention group compared to the control group. In two studies (2380 children), WAZ decreased in both groups. In one of these studies (1318 children), the decrease in the intervention group was significantly smaller than in the control group. In the other study (1062 children), there was no difference between the groups.Three studies (1612 children) reported impacts on all-cause morbidity, but metrics were inconsistent between studies. One study with yogurt (402 children) reported a significant reduction in duration and incidence of diarrhea and upper respiratory infections in the intervention group. One study with eggs (148 children) reported a significant increase in the incidence of diarrhea in the intervention group, but this may have been due to cultural associations with eggs and gastrointestional problems. There were no other significant differences in fever, respiratory infections, or skin conditions between groups. The third study (1062 children) found no differences between intervention and control groups across morbidity measures.No studies reported data on anemia.Meat-based diet versus dairy-based dietOne study (64 children) measured change in LAZ and WAZ in infants fed either a meat-based diet or dairy-based diet. There was a significant increase in LAZ among infants consuming the meat-based diet and a significant decrease in LAZ among infants consuming a dairy-based diet. WAZ increased in both groups, with no significant difference between groups.The study did not assess all-cause morbidity or anemia.Quality of the evidenceWe rated the quality of the evidence as very low overall due to baseline imbalances between intervention and control groups, high heterogeneity in meta-analysis, and imprecision due to wide confidence intervals and inconsistent direction of effects. We have little confidence in the results; further research is likely to change the estimate of magnitude and direction of treatment effect.

**AUTHORS&#039; CONCLUSIONS:**
Given the limited quality of the evidence, we are uncertain of the effects of the provision of animal-source food versus cereal products or no intervention on the growth or development of children. More adequately powered trials with deliberately selected animal-source foods are needed.
AU  - Eaton,
AU  - J.
AU  - C.
AU  - Rothpletz-Puglia,
AU  - P.
AU  - Dreker,
AU  - M.
AU  - R.
AU  - Iannotti,
AU  - L.
AU  - Lutter,
AU  - C.
AU  - Kaganda,
AU  - J.
AU  - Rayco-Solon,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD012818.pub2.
L1  - internal-pdf://4163138355/Eaton-2019-Effectiveness of provision of anima.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Effectiveness of provision of animal-source foods forsupporting optimal growth and development in children 6 to59 months of age
ER  -
TY  - JOUR
AB  - This network meta-analysis assessed the efficacy and tolerability of lurasidone versus other oral atypical antipsychotic monotherapies in adolescent schizophrenia. A systematic literature review identified 13 randomized controlled trials of antipsychotics in adolescents with schizophrenia-spectrum disorders. A Bayesian network meta-analysis compared lurasidone to aripiprazole, asenapine, clozapine, olanzapine, paliperidone extended-release (ER), quetiapine, risperidone, and ziprasidone. Outcomes included Positive and Negative Syndrome Scale (PANSS), Clinical Global Impressions-Severity (CGI-S), weight gain, all-cause discontinuation, extrapyramidal symptoms (EPS), and akathisia. Results were reported as median differences for continuous outcomes and odds ratios (ORs) for binary outcomes, along with 95% credible intervals (95% CrI). Lurasidone was significantly more efficacious than placebo on the PANSS (- 7.95, 95% CrI - 11.76 to - 4.16) and CGI-S (- 0.44, 95% CrI - 0.67 to - 0.22) scores. Lurasidone was associated with similar weight gain to placebo and statistically significantly less weight gain versus olanzapine (- 3.62 kg, 95% CrI - 4.84 kg to - 2.41 kg), quetiapine (- 2.13 kg, 95% CrI - 3.20 kg to - 1.08 kg), risperidone (- 1.16 kg, 95% CrI - 2.14 kg to - 0.17 kg), asenapine (- 0.98 kg, 95% CrI - 1.71 kg to - 0.24 kg), and paliperidone ER (- 0.85 kg, 95% CrI - 1.57 kg to - 0.14 kg). The odds of all-cause discontinuation were significantly lower for lurasidone than aripiprazole (OR = 0.28, 95% CrI 0.10-0.76) and paliperidone ER (OR = 0.25, 95% CrI 0.08-0.81) and comparable to other antipsychotics. Rates of EPS and akathisia were similar for lurasidone and other atypical antipsychotics. In this network meta-analysis of atypical antipsychotics in adolescent schizophrenia, lurasidone was associated with similar efficacy, less weight gain, and lower risk of all-cause discontinuation compared to other oral atypical antipsychotics. Copyright &copy; 2019, The Author(s).
AD  - (Arango) Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon. IiSGM, School of Medicine, Universidad Complutense, CIBERSAM. Av. Seneca 2, Madrid 28040, Spain (Ng-Mak) Sunovion Pharmaceuticals Inc, 84 Waterford Drive, Marlborough, MA 01752, United States (Finn, Byrne) IQVIA, 210 Pentonville Rd, London N1 9JY, United Kingdom (Loebel) Sunovion Pharmaceuticals Inc, One Bridge Plaza North, Suite 510, Fort Lee, NJ 07024, United StatesD. Ng-Mak, Sunovion Pharmaceuticals Inc, 84 Waterford Drive, Marlborough, MA 01752, United States. E-mail: Daisy.Ng-Mak@Sunovion.com
AU  - Arango,
AU  - C.
AU  - Ng-Mak,
AU  - D.
AU  - Finn,
AU  - E.
AU  - Byrne,
AU  - A.
AU  - Loebel,
AU  - A.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s00787-019-01425-2
DP  - Ovid UI - 2003719832
KW  - Adolescent
KW  - Body weight changes
KW  - Lurasidone
KW  - Network meta-analysis
KW  - Schizophrenia
KW  - akathisia
KW  - article
KW  - Bayesian network
KW  - body weight gain
KW  - Clinical Global Impression scale
KW  - comparative effectiveness
KW  - drug efficacy
KW  - drug therapy
KW  - drug withdrawal
KW  - female
KW  - human
KW  - male
KW  - meta analysis
KW  - monotherapy
KW  - negative syndrome
KW  - Positive and Negative Syndrome Scale
KW  - positive syndrome
KW  - randomized controlled trial (topic)
KW  - systematic review
KW  - aripiprazole
KW  - asenapine
KW  - clozapine
KW  - olanzapine
KW  - paliperidone
KW  - placebo
KW  - quetiapine
KW  - risperidone
KW  - ziprasidone
L1  - internal-pdf://1420012521/Arango-2019-Lurasidone compared to other atypi.pdf
LA  - English
N1  - Using Smart Source ParsingDate of Publication: 2019
PY  - 2019
T2  - European Child and Adolescent Psychiatry.
TI  - Lurasidone compared to other atypical antipsychotic monotherapies for adolescent schizophrenia: a systematic literature review and network meta-analysis
UR  - http://www.springerlink.com/content/1018-8827
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2003719832
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:31758359&amp;id=doi:10.1007%2Fs00787-019-01425-2&amp;issn=1018-8827&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2019&amp;title=European+Child+and+Adolescent+Psychiatry&amp;atitle=Lurasidone+compared+to+other+atypical+antipsychotic+monotherapies+for+adolescent+schizophrenia%3A+a+systematic+literature+review+and+network+meta-analysis&amp;aulast=Arango&amp;pid=%3Cauthor%3EArango+C.%3C%2Fauthor%3E%3CAN%3E2003719832%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007%2Fs00787-019-01425-2.pdf
ER  -
TY  - JOUR
AB  - A significant number of children and adolescents with obsessive compulsive disorder (OCD) demonstrate poor response to the current gold standard treatment, cognitive behaviour therapy (CBT) with exposure and response prevention (ERP). Recent findings suggest that family variables affect treatment response highlighting the need for a meta-analytic review of the precise impact of family variables on OCD-related symptoms and processes. The current review and meta-analysis examined the effect of family-based interventions on OCD symptom and family factor outcomes for children and adolescents with OCD. The moderating effects of the degree of parental involvement and number of family factors targeted in treatment were investigated. An extensive literature search identified 37 eligible studies (1727 OCD participants). Large significant pooled mean effect sizes for OCD symptoms and Family Accommodation (FA), respectively, were obtained at posttest (g = 1.56; g = 1.00) and follow-up (g = 1.69; g = 1.98). Moderator analyses indicated that the number of family factors targeted in treatment significantly moderated outcomes on measures of FA (z = 2.21, p = 0.03), but not on Children&#039;s/Yale-Brown Obsessive Compulsive Scale (C/Y-BOCS) outcomes. FA has been significantly correlated with OCD symptom severity and poorer treatment outcomes, and there is data to suggest that FA may mediate OCD symptom outcomes (e.g., Piacentini et al. in J Am Acad Child Adolesc Psychiatry 50:1149-1161, 2011). Findings show that the greater the number of family factors targeted, the greater the reduction in FA at post, highlighting the importance of addressing a range of family factors in child OCD treatment to optimise outcomes.
AN  - 31240488
AU  - McGrath,
AU  - C.
AU  - A.
AU  - Abbott,
AU  - M.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-019-00296-y
L1  - internal-pdf://1403054385/McGrath-2019-Family-Based Psychological Treatm.pdf
PY  - 2019
SP  - 25
T2  - Clinical Child &amp; Family Psychology Review
TI  - Family-Based Psychological Treatment for Obsessive Compulsive Disorder in Children and Adolescents: A Meta-analysis and Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31240488
UR  - https://link.springer.com/article/10.1007%2Fs10567-019-00296-y
VL  - 25
ER  -
TY  - JOUR
AB  - Children with autism spectrum disorders (ASDs) often demonstrate delays in early language and literacy skills. 

Shared reading, the practice of adults reading aloud to children while using behaviors (e.g., asking questions) that are meant to promote interaction between the adult and child, is an intervention that has had positive effects on those early skills for typically developing children. 

A meta-analysis of 11 shared reading interventions with children with ASD was conducted, and positive effects were found for listening comprehension, expressive communication, and other communicative and noncommunicative acts. 

Copyright &copy; Hammill Institute on Disabilities 2019.
AN  - 627694243
AU  - Boyle,
AU  - S.
AU  - A.
AU  - McNaughton,
AU  - D.
AU  - Chapin,
AU  - S.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1088357619838276
L1  - internal-pdf://1045991115/Boyle-2019-Effects of Shared Reading on the Ea.pdf
PY  - 2019
T2  - Focus on Autism and Other Developmental Disabilities.
TI  - Effects of Shared Reading on the Early Language and Literacy Skills of Children With Autism Spectrum Disorders: A Systematic Review
UR  - http://www.sagepub.com/journalsProdDesc.nav?prodId=Journal201875
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
This meta-analysis examines the efficacy of recently developed psychological treatments for anorexia nervosa, compared with control condition. Outcome criteria are weight gain, eating disorder pathology, and quality of life. 

**METHOD: **
Twelve thousand nine hundred ninety-seven abstracts, published between 1980 and 2017, were retrieved. End-of-treatment data from 1,279 participants, from 15 of 17 eligible studies, were used to calculate pooled-effect sizes (Hedges&#039; g) for outcome using random-effects model. Subgroup analyses were used to explore the influence of various patient and study characteristics. 

**RESULTS: **
No significant differences between psychological treatment and controls were found on weight gain, g = 0.07, 95% CI [-0.09, 0.23], eating disorder pathology, g = 0.06, 95% CI [-0.10, 0.21], and quality of life, g = -0.11, 95% CI [-0.36, 0.15]. Studies including only patients over 18 years of age were more effective on weight gain than studies including adolescents as well. High-quality studies and studies with reported therapist training had larger effects on weight gain and quality of life compared with low-quality studies and studies without reported training. 

**CONCLUSIONS: **
Despite progress in the development of specialized treatments, the efficacy of psychological treatment over an active control condition could not be established. Outcomes, however, are obscured by low-quality and heterogeneous studies.
AN  - 31124215
AU  - van
AU  - den
AU  - Berg,
AU  - E.
AU  - Houtzager,
AU  - L.
AU  - de
AU  - Vos,
AU  - J.
AU  - Daemen,
AU  - I.
AU  - Katsaragaki,
AU  - G.
AU  - Karyotaki,
AU  - E.
AU  - Cuijpers,
AU  - P.
AU  - Dekker,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/erv.2683
L1  - internal-pdf://2731972861/van den Berg-2019-Meta-analysis on the efficac.pdf
PY  - 2019
SP  - 23
T2  - European Eating Disorders Review
TI  - Meta-analysis on the efficacy of psychological treatments for anorexia nervosa
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31124215
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1002/erv.2683
VL  - 23
ER  -
TY  - JOUR
AB  - Schools are the only institution regularly reaching the majority of school-age children and adolescents across the globe. Although at least 102 countries have school health services, there is no rigorous, evidence-based guidance on which school health services are effective and should be implemented in schools. To investigate the effectiveness of school health services for improving the health of school-age children and adolescents, a systematic review of systematic reviews (overview) was conducted. 

Five databases were searched through June 2018. Systematic reviews of intervention studies that evaluated school-based or school-linked health services delivered by a health provider were included. Review quality was assessed using a modified Ballard and Montgomery four-item checklist. 1654 references were screened and 20 systematic reviews containing 270 primary studies were assessed narratively. Interventions with evidence for effectiveness addressed autism, depression, anxiety, obesity, dental caries, visual acuity, asthma, and sleep. No review evaluated the effectiveness of a multi-component school health services intervention addressing multiple health areas. 

From the limited amount of information available in existing systematic reviews, the strongest evidence supports implementation of anxiety prevention programs, indicated asthma education, and vision screening with provision of free spectacles. Additional systematic reviews are needed that analyze the effectiveness of comprehensive school health services, and specific services for under-researched health areas relevant for this population.
AN  - 31188826
AU  - Levinson,
AU  - J.
AU  - Kohl,
AU  - K.
AU  - Baltag,
AU  - V.
AU  - Ross,
AU  - D.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0212603
L1  - internal-pdf://2210570691/Levinson-2019-Investigating the effectiveness.pdf
PY  - 2019
SP  - e0212603
T2  - PLoS ONE [Electronic Resource]
TI  - Investigating the effectiveness of school health services delivered by a health provider: A systematic review of systematic reviews
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31188826
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0212603&amp;type=printable
VL  - 14
ER  -
TY  - JOUR
AB  - Difficulty performing age-appropriate motor skills affects up to 83% of children with autism spectrum disorder. This systematic review examined the effect of motor and physical activity intervention on motor outcomes of children with autism spectrum disorder and the effect of motor learning strategies on motor skill acquisition, retention, and transfer. 

Six databases were searched from 2000 to 2019. Forty-one studies were included: 34 intervention studies and 7 motor learning studies. The overall quality of the evidence was low. Participants included 1173 children with autism spectrum disorder ranging from 3 to 19 years. 

Results from level II and III intervention studies supported that participation outcomes improved with a physical education intervention; activity outcomes improved with aquatic, motor activity, motor skill, and simulated horse riding interventions; and body structure and function outcomes improved with aquatic, exergaming, motor activity, motor skill, and simulated horse riding interventions. Results from level II and III motor learning studies supported that motor skill acquisition improved with visual, versus verbal, instructions but was not influenced by differences in instructional personnel. More rigorous research on motor intervention is needed with well-controlled study designs, adequate sample sizes, and manualized protocols. In addition, research on motor learning strategies is warranted as it generalizes across motor interventions.
AD  - Ruggeri, Anneliese. Children&#039;s Hospital Los Angeles, USA.Ruggeri, Anneliese. University of Southern California, USA.Dancel, Alina. Children&#039;s Hospital Los Angeles, USA.Dancel, Alina. University of Southern California, USA.Johnson, Robert. University of Southern California, USA.Sargent, Barbara. University of Southern California, USA.
AN  - 31782658
AU  - Ruggeri,
AU  - A.
AU  - Dancel,
AU  - A.
AU  - Johnson,
AU  - R.
AU  - Sargent,
AU  - B.
DA  - Nov 
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1177/1362361319885215
DP  - Ovid Technologies
J2  - Autism
L1  - internal-pdf://3026497677/Ruggeri-2019-The effect of motor and physical.pdf
LA  - English
N1  - Ruggeri, AnnelieseDancel, AlinaJohnson, RobertSargent, Barbara
PY  - 2019
SP  - 1362361319885215
T2  - Autism
TI  - The effect of motor and physical activity intervention on motor outcomes of children with autism spectrum disorder: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31782658
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31782658&amp;id=doi:10.1177%2F1362361319885215&amp;issn=1362-3613&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1362361319885215&amp;pages=1362361319885215&amp;date=2019&amp;title=Autism&amp;atitle=The+effect+of+motor+and+physical+activity+intervention+on+motor+outcomes+of+children+with+autism+spectrum+disorder%3A+A+systematic+review.&amp;aulast=Ruggeri&amp;pid=%3Cauthor%3ERuggeri+A%3C%2Fauthor%3E%3CAN%3E31782658%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1362361319885215
ER  -
TY  - JOUR
AB  - **Background:** 
Lifestyle risk behaviours typically emerge during adolescence, track into adulthood, and commonly co-occur. Interventions targeting multiple risk behaviours in adolescents have the potential to efficiently improve health outcomes, yet further evidence is required to determine their effect. We reviewed the effectiveness of eHealth school-based interventions targeting multiple lifestyle risk behaviours. 

**Method(s):** 
In this systematic review and meta-analysis, we searched Ovid MEDLINE, Embase, PsycINFO, and the Cochrane Library databases between Jan 1, 2000, and March 14, 2019, with no language restrictions, for publications on school-based eHealth multiple health behaviour interventions in humans. We also screened the grey literature for unpublished data. Eligible studies were randomised controlled trials of eHealth (internet, computers, tablets, mobile technology, or tele-health) interventions targeting two or more of six behaviours of interest: alcohol use, smoking, diet, physical activity, sedentary behaviour, and sleep. Primary outcomes of interest were the prevention or reduction of unhealthy behaviours, or improvement in healthy behaviours of the six behaviours. Outcomes were summarised in a narrative synthesis and combined using random-effects meta-analysis. This systematic review is registered with PROSPERO, identifier CRD42017072163. 

**Finding(s):** 
Of 10 571 identified records, 22 publications assessing 16 interventions were included, comprising 18 873 students, of whom on average 56.2% were female, with a mean age of 13.41 years (SD 1.52). eHealth school-based multiple health behaviour change interventions significantly increased fruit and vegetable intake (standard mean difference 0.11, 95% CI 0.03 to 0.19; p=0.007) and both accelerometer-measured (0.33, 0.05 to 0.61; p=0.02) and self-reported (0.14, 0.05 to 0.23; p=0.003) physical activity, and reduced screen time (-0.09, -0.17 to -0.01; p=0.03) immediately after the intervention; however, these effects were not sustained at follow-up when data were available. No effect was seen for alcohol or smoking, fat or sugar-sweetened beverage or snack consumption. No studies examined sleep or used mobile health interventions. The risk of bias in masking of final outcome assessors and selective outcome reporting was high or unclear across studies and overall we deemd the quality of evidence to be low to very low. 

**Interpretation(s):** 
eHealth school-based interventions addressing multiple lifestyle risk behaviours can be effective in improving physical activity, screen time, and fruit and vegetable intake. However, effects were small and only evident immediately after the intervention. Further high quality, adolescent-informed research is needed to develop eHealth interventions that can modify multiple behaviours and sustain long-term effects. 

**Funding(s):** 
Paul Ramsay Foundation and Australian National Health and Medical Research Council. Copyright &copy; 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
AD  - (Champion, Gardner, Thornton, Barrett, Teesson, Newton) The Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW, Australia (Champion, McGowan, Spring) Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States (Wafford) Galter Health Sciences Library, Northwestern University Feinberg School of Medicine, Chicago, IL, United States (Parmenter) Department of Exercise Physiology, School of Medical Sciences, UNSW Sydney, Sydney, NSW, Australia (McBride) National Drug Research Institute, Curtin University, Perth, WA, AustraliaK.E. Champion, The Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, NSW 2006, Australia. E-mail: katrina.champion@sydney.edu.au
AN  - 2002789929
AU  - Champion,
AU  - K.
AU  - E.
AU  - Parmenter,
AU  - B.
AU  - McGowan,
AU  - C.
AU  - Spring,
AU  - B.
AU  - Wafford,
AU  - Q.
AU  - E.
AU  - Gardner,
AU  - L.
AU  - A.
AU  - Thornton,
AU  - L.
AU  - McBride,
AU  - N.
AU  - Barrett,
AU  - E.
AU  - L.
AU  - Teesson,
AU  - M.
AU  - Newton,
AU  - N.
AU  - C.
AU  - Chapman,
AU  - C.
AU  - Slade,
AU  - T.
AU  - Sunderland,
AU  - M.
AU  - Bauer,
AU  - J.
AU  - Allsop,
AU  - S.
AU  - Hides,
AU  - L.
AU  - Stapinksi,
AU  - L.
AU  - Birrell,
AU  - L.
AU  - Mewton,
AU  - L.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/S2589-7500%2819%2930088-3
DP  - Ovid Technologies
KW  - alcohol consumption
KW  - article
KW  - behavior change
KW  - clinical effectiveness
KW  - diet
KW  - follow up
KW  - food intake
KW  - human
KW  - Internet
KW  - lifestyle
KW  - physical activity
KW  - randomized controlled trial (topic)
KW  - risk factor
KW  - screen time
KW  - sedentary lifestyle
KW  - self report
KW  - smoking
KW  - sugar-sweetened beverage
KW  - systematic review
KW  - tablet
KW  - telehealth
KW  - accelerometer
KW  - computer
L1  - internal-pdf://0606434613/Champion-2019.pdf
LA  - English
PY  - 2019
SP  - 206-221
T2  - The Lancet Digital Health
TI  - Effectiveness of school-based eHealth interventions to prevent multiple lifestyle risk behaviours among adolescents: a systematic review and meta-analysis
UR  - https://www.sciencedirect.com/journal/the-lancet-digital-health
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2002789929
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2FS2589-7500%252819%252930088-3&amp;issn=2589-7500&amp;isbn=&amp;volume=1&amp;issue=5&amp;spage=e206&amp;pages=e206-e221&amp;date=2019&amp;title=The+Lancet+Digital+Health&amp;atitle=Effectiveness+of+school-based+eHealth+interventions+to+prevent+multiple+lifestyle+risk+behaviours+among+adolescents%3A+a+systematic+review+and+meta-analysis&amp;aulast=Champion&amp;pid=%3Cauthor%3EChampion+K.E.%3C%2Fauthor%3E%3CAN%3E2002789929%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
VL  - 1
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** 
To compare antidepressant-related adverse events (AEs), suicidality and AE-related discontinuation in double-blind, placebo-controlled trials of pediatric patients with OCD and anxiety disorders treated with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs).

**METHOD:** 
MEDLINE, PubMed, Web of Science, PsycINFO and Embase were searched for peer-reviewed, English-language articles from inception through March 1, 2019. We identified prospective, randomized, SSRI and SNRI studies in patients &lt;18 years of age with OCD, generalized, separation or social anxiety disorders. AE rates were extracted and antidepressant-placebo differences examined using Bayesian hierarchical models (BHM) then posterior estimates of relative risk (RR) was determined for each AE by medication class and disorder.

**RESULTS:** 
Data were included from 18 trials (2631 patients) and 7 medications (16 SSRI and 4 SNRI trials). Compared to placebo, SSRIs were associated with a greater likelihood of AE-related discontinuation (RR: 3.59, CrI: 0.019 to 0.067, p=0.0003), activation (RR: 2.39, CrI: 0.048 to 0.125, p=0.003), sedation (RR: 1.94, CrI: 0.035 to 0.157, p=0.002), insomnia (RR: 1.93, CrI: 0.040 to 0.149, p=0.001), abdominal pain (RR: 1.53, Credible Interval [CrI]: 0.032 to 0.164, p=0.005) and headache (RR: 1.24, CrI: 0.003 to 0.139, p=0.04). Activation was more common with SSRI (vs. SNRIs, RR: 1.32, CrI: 0.018 to 0.114, p=0.007). Neither SSRIs nor SNRIs were associated with treatment-emergent suicidality.

**CONCLUSION:** 
In pediatric OCD and anxiety disorders, SSRIs (compared to placebo) are associated with distinct adverse events (AEs) and greater AE-related discontinuation, although their tolerability does not differ between anxiety disorders and OCD. Compared to SNRIs, SSRIs are more likely to produce activation. Class-related AEs are important for clinicians to consider, particularly in light of data suggesting differences in class-related efficacy. While SSRIs are superior to SNRIs and the treatment of choice for anxiety, for youth who become activated on SSRIs, SNRIs might represent a good second choice given their reported efficacy and lower risk of activation.
AD  - Mills, Jeffrey A. Carl H. Lindner College of Business, University of Cincinnati, OH.Strawn, Jeffrey R. College of Medicine, University of Cincinnati, and the Cincinnati Children&#039;s Hospital Medical Center, OH. Electronic address: strawnjr@uc.edu.
AN  - 31682918
AU  - Mills,
AU  - J.
AU  - A.
AU  - Strawn,
AU  - J.
AU  - R.
DA  - Nov 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2019.10.013
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
L1  - internal-pdf://2639352442/Mills-2019-Antidepressant Tolerability in Pedi.pdf
LA  - English
N1  - Using Smart Source ParsingNovMills, Jeffrey AStrawn, Jeffrey RS0890-8567(19)32113-6
PY  - 2019
SP  - 01
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Antidepressant Tolerability in Pediatric Anxiety and Obsessive-Compulsive Disorders: A Bayesian Hierarchical Modeling Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31682918
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31682918&amp;id=doi:10.1016%2Fj.jaac.2019.10.013&amp;issn=0890-8567&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2019&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Antidepressant+Tolerability+in+Pediatric+Anxiety+and+Obsessive-Compulsive+Disorders%3A+A+Bayesian+Hierarchical+Modeling+Meta-Analysis.&amp;aulast=Mills&amp;pid=%3Cauthor%3EMills+JA%3C%2Fauthor%3E%3CAN%3E31682918%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pdf.sciencedirectassets.com/279787/AIP/1-s2.0-S0890856719321136/main.pdf?X-Amz-Security-Token=IQoJb3JpZ2luX2VjEND%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJHMEUCICzDF8Ja2bY78EQybn7ciGYpDsCbnDEGej1DJD%2F7NDZ4AiEAycgzXnxEyI3%2FeRO72eAIM3WQ2vSPy6IOPi2j98guN9Uq0AIIKBACGgwwNTkwMDM1NDY4NjUiDP91%2FdWqapfiEdcpqiqtAtCMzvddXMpr%2BbZz4MTE0xJuvyNHB60VCWFJJKnmMW54FRJLEi%2B9OLPozNSX769ol7BaEfwAfo2MdLnX0JzpLcjOsgyWpPgmBy5NialqhjDoxUkeFEzh3Q0yzsEQG9CZLYj8%2BEdro7wZB%2BGV8LXc4N57XQ0i0fXBdubCrGHhKjXcFiCrNxfDJHCj%2F3nVTcMo1%2FLe%2FKWQLAw8TziwyZAJ33ftTLu5ZD5Iz3vP6Zaw73vFNFJWR0JTJpXcWVS8JW%2FAGEW7SPQVb%2FAuiAsMVdtQUSfJbjCiKCCEQ6FPtnPv8tbod6lW4Cs0n0XH3vBy2O2cA%2FbPwn%2B3xDCO4TKSFdsTtmfLj%2BiNrskVXno%2FHVTN7gjlYIWD9MvsbIg8wa5yqDvg45fKH9H0qEJJlX0tJ6ww5PXM7wU6zwJUKkKc6aSlYMYFMKRfftQINUXWnAob6fLSf6OFAuIsptF6%2BQhIX1K9gG2OatRHihNqTWnRhjj6DYe9BlLz7xPCjqIkoVHnyoNmSdiizkN4o1%2BjMMP1%2Bqm5D6iewMM%2F%2F51UfhVbDUKaEKnsrJDT1xkhcYvS6VMT4%2FpRCiRM4p7Ac8YHq7uyWW7Zps15sQgJsF5qErHmx8x4NtqQoC17L2rQNc5oM5Z%2FO5vvUzQloFPZYJ4W4fT%2Bq78mnU%2BRYxtUvIMWyxamYzEs4Z5EQVbFij04je0eADlZwC8ZLwJEJgCXIC0d5ySKn4dumXsdtSULYWA5CRrMA7q516ZkYoNiQzoqqIBCJbZJIMvfv%2FC4OlFprQXne8HXZM9NbtPBeejJPhGIePQzjYZvt1hru77lHAiAJiRv1%2FPpRxXb7ofYGOLl%2FKze1MQxxK%2FXzbJVK9xNvQ%3D%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20191213T090116Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY7P4CYCKD%2F20191213%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=0fbb49cd6159d502474ba6684518bfdf028c070b802f61ec75440d9c2b0ce78f&amp;hash=266e029a6a45d901a7e28546fa2e75020eff5d5aaf3197a05ef69d9726947cf2&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0890856719321136&amp;tid=spdf-471e5b10-1773-497d-a2eb-ea588e859634&amp;sid=1c47b7374b651743b25aa4713ec30aabc77cgxrqb&amp;type=client
VL  - 01
ER  -
TY  - JOUR
AB  - Understanding variables predicting drop-out or unfavourable outcome following treatment for anorexia nervosa (AN) may help to improve upon intervention efforts. However, the current literature has demonstrated sparse and inconsistent significant findings. 

The current systematic review and meta-analysis summarised the evidence base examining baseline predictors of drop-out and outcome in AN treatment. A literature search was conducted to identify research investigating predictors of drop-out and outcome in individuals treated for AN. 

Four online databases were searched, and predictors were organised by category and dependent variable (outcome versus drop-out). 27 studies were included. Lower motivation, lower BMI, and having the binge-purge subtype of AN predicted drop-out. 

Greater ED pathology and poorer motivation predicted poorer outcome. Clinical recommendations include taking particular care during assessment stages to identify patients at risk of drop-out and/or poor outcome based on their clinical profile and level of motivation for recovery. 

At-risk patients should be receiving tailored treatment to enhance engagement and reduce risk of drop-out. In conclusion, there&#039;s some evidence that motivation, BMI, subtype, and ED pathology predicts drop-out and/or outcome in individual and family-based therapy for AN amongst adolescents and adults; however, research incorporating carefully designed multi-site studies is required to further examine these findings. 

Copyright &copy; 2018
AU  - Gregertsen,
AU  - E.
AU  - C.
AU  - Mandy,
AU  - W.
AU  - Kanakam,
AU  - N.
AU  - Armstrong,
AU  - S.
AU  - Serpell,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.psychres.2018.11.068
L1  - internal-pdf://1141444883/Gregertsen-2019-Pre-treatment patient characte.pdf
PY  - 2019
SP  - 484-501
T2  - Psychiatry Research
TI  - Pre-treatment patient characteristics as predictors of drop-out and treatment outcome in individual and family therapy for adolescents and adults with anorexia nervosa: A systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/psychres
UR  - https://ac.els-cdn.com/S0165178117320152/1-s2.0-S0165178117320152-main.pdf?_tid=b99df464-93fa-478e-927c-b6a8ed320c43&amp;acdnat=1547554193_9eb5f4cb3de73179f3cd7beedffac975
VL  - 271
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
The prevalence of certain neurodevelopmental disorders, specifically autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD), has been increasing over the last four decades. Nonpharmacological interventions are available that can improve outcomes and reduce associated symptoms such as anxiety, but these are often difficult to access. Children and young people are using the internet and digital technology at higher rates than any other demographic, but although Web-based interventions have the potential to improve health outcomes in those with long-term conditions, no previous reviews have investigated the effectiveness of Web-based interventions delivered to children and young people with neurodevelopmental disorders.OBJECTIVE: This study aimed to review the effectiveness of randomized controlled trials (RCTs) of Web-based interventions delivered to children and young people with neurodevelopmental disorders.

**METHODS:** 
Six databases and one trial register were searched in August and September 2018. RCTs were included if they were published in a peer-reviewed journal. Interventions were included if they (1) aimed to improve the diagnostic symptomology of the targeted neurodevelopmental disorder or associated psychological symptoms as measured by a valid and reliable outcome measure; (2) were delivered on the Web; (3) targeted a youth population (aged &lt;=18 years or reported a mean age of &lt;=18 years) with a diagnosis or suspected diagnosis of a neurodevelopmental disorder. Methodological quality was rated using the Joanna Briggs Institute Critical Appraisal Checklist for RCTs.

**RESULTS:** 
Of 5140 studies retrieved, 10 fulfilled the inclusion criteria. Half of the interventions were delivered to children and young people with ASDs with the other five targeting ADHD, tic disorder, dyscalculia, and specific learning disorder. In total, 6 of the 10 trials found that a Web-based intervention was effective in improving condition-specific outcomes or reducing comorbid psychological symptoms in children and young people. The 4 trials that failed to find an effect were all delivered by apps. The meta-analysis was conducted on five of the trials and did not show a significant effect, with a high level of heterogeneity detected (n=182 [33.4%, 182/545], 5 RCTs; pooled standardized mean difference=-0.39; 95% CI -0.98 to 0.20; Z=-1.29; P=.19 [I&lt;sup&gt;2&lt;/sup&gt;=72%; P=.006]).

**CONCLUSIONS:** 
Web-based interventions can be effective in reducing symptoms in children and young people with neurodevelopmental disorders; however, caution should be taken when interpreting these findings owing to methodological limitations, the minimal number of papers retrieved, and small samples of included studies. Overall, the number of studies was small and mainly limited to ASD, thus restricting the generalizability of the findings.

TRIAL REGISTRATION: PROSPERO International Prospective Register of Systematic Reviews: CRD42018108824; http://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42018108824.
AD  - Khan, Kareem. Division of Psychiatry and Applied Psychology, Institute of Mental Health, University of Nottingham, Nottingham, United Kingdom.Hall, Charlotte L. Division of Psychiatry and Applied Psychology, Institute of Mental Health, University of Nottingham, Nottingham, United Kingdom.Davies, E Bethan. Division of Psychiatry and Applied Psychology, Institute of Mental Health, University of Nottingham, Nottingham, United Kingdom.Davies, E Bethan. NIHR MindTech Medtech Co-operative, Institute of Mental Health, University of Nottingham, Nottingham, United Kingdom.Hollis, Chris. Division of Psychiatry and Applied Psychology, Institute of Mental Health, University of Nottingham, Nottingham, United Kingdom.Hollis, Chris. NIHR MindTech Medtech Co-operative, Institute of Mental Health, University of Nottingham, Nottingham, United Kingdom.Hollis, Chris. NIHR Nottingham Biomedical Research Centre, Nottingham, United Kingdom.Glazebrook, Cris. Division of Psychiatry and Applied Psychology, Institute of Mental Health, University of Nottingham, Nottingham, United Kingdom.Glazebrook, Cris. NIHR MindTech Medtech Co-operative, Institute of Mental Health, University of Nottingham, Nottingham, United Kingdom.
AN  - 31682573
AU  - Khan,
AU  - K.
AU  - Hall,
AU  - C.
AU  - L.
AU  - Davies,
AU  - E.
AU  - B.
AU  - Hollis,
AU  - C.
AU  - Glazebrook,
AU  - C.
DA  - Nov 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2196/13478
DP  - Ovid Technologies
J2  - J Med Internet Res
L1  - internal-pdf://1697074865/download (40).pdf
LA  - English
M3  - Review
N1  - Khan, KareemHall, Charlotte LDavies, E BethanHollis, ChrisGlazebrook, Cris
PY  - 2019
SP  - e13478
T2  - Journal of Medical Internet Research
TI  - The Effectiveness of Web-Based Interventions Delivered to Children and Young People With Neurodevelopmental Disorders: Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31682573
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31682573&amp;id=doi:10.2196%2F13478&amp;issn=1438-8871&amp;isbn=&amp;volume=21&amp;issue=11&amp;spage=e13478&amp;pages=e13478&amp;date=2019&amp;title=Journal+of+Medical+Internet+Research&amp;atitle=The+Effectiveness+of+Web-Based+Interventions+Delivered+to+Children+and+Young+People+With+Neurodevelopmental+Disorders%3A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Khan&amp;pid=%3Cauthor%3EKhan+K%3C%2Fauthor%3E%3CAN%3E31682573%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 21
ER  -
TY  - JOUR
AB  - AIM: We performed a systematic review and meta-analysis to evaluate the efficacy of electrical stimulation (ES) in treating children with nocturnal enuresis (NE).

METHODS: Randomized controlled trials (RCTs) of the use of ES for the treatment of NE in children were searched using EMBASE, MEDLINE, and the Cochrane Controlled Trials Register. The references of related articles were also searched. The systematic review was carried out using the Preferred Reporting Items for Systematic Reviews and Meta-analyses.

RESULTS: Four RCTs involving 171 patients were studied. We found that there was statistically significant difference in the wet nights per week (mean difference [MD], -0.70; 95% confidence interval [CI], -0.89 to -0.51; P &lt; .00001), the number of patients with clinical response (MD, 26.88; 95% CI, 11.16 to 64.74; P &lt; .00001), and bladder capacity (MD, -0.70; 95% CI -0.89 to -0.51; P &lt; .00001) in the ES group compared with the placebo group with the exception of maximum voided volume (MVV) (MD, 19.48; 95% CI, -9.18 to 48.14; P = .18).

CONCLUSIONS: The study provides a significant improvement in statistics in the wet nights per week, the number of patients with clinical response and bladder capacity for children with NE compared with the placebo group with the exception of MVV.
AD  - Cui, Huanqin. Department of Pediatrics, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, China.Yu, Wentao. Department of Pediatrics, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, China.Yu, Wentao. Department of General Surgery, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, China.Yan, Huilei. Department of Urology, Liaocheng People&#039;s Hospital, Liaocheng, China.Zhou, Zhongbao. Department of Urology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, China.Wu, Jitao. Department of Urology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, China.Cui, Yuanshan. Department of Urology, Yantai Yuhuangding Hospital Affiliated to Qingdao University, Yantai, China.
AN  - 31397008
AU  - Cui,
AU  - H.
AU  - Yu,
AU  - W.
AU  - Yan,
AU  - H.
AU  - Zhou,
AU  - Z.
AU  - Wu,
AU  - J.
AU  - Cui,
AU  - Y.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/nau.24136
DP  - Ovid Technologies
J2  - Neurourol Urodyn
KW  - Adolescent
KW  - Child, Preschool
KW  - *Electric Stimulation Therapy/mt [Methods]
KW  - Humans
KW  - Infant
KW  - *Nocturnal Enuresis/th [Therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
L1  - internal-pdf://0911177185/Cui-2019.pdf
LA  - English
M3  - Meta-Analysis
Research Support, Non-U.S. Gov&#039;t
Systematic Review
N1  - Cui, HuanqinYu, WentaoYan, HuileiZhou, ZhongbaoWu, JitaoCui, YuanshanComment in (CIN)
PY  - 2019
SP  - 2288-2295
T2  - Neurourology &amp; Urodynamics
TI  - The efficacy of electrical stimulation in treating children with nocturnal enuresis: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=31397008
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31397008&amp;id=doi:10.1002%2Fnau.24136&amp;issn=0733-2467&amp;isbn=&amp;volume=38&amp;issue=8&amp;spage=2288&amp;pages=2288-2295&amp;date=2019&amp;title=Neurourology+%26+Urodynamics&amp;atitle=The+efficacy+of+electrical+stimulation+in+treating+children+with+nocturnal+enuresis%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Cui&amp;pid=%3Cauthor%3ECui+H%3C%2Fauthor%3E%3CAN%3E31397008%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/full/10.1002/nau.24136
VL  - 38
ER  -
TY  - JOUR
AB  - **Innledning** 
Helsefremmende og sykdomsforebyggende tiltak tar utgangspunkt i helsedeterminanter, og tiltak er rettet mot å påvirke disse. Primærforebyggende tiltak har til hensikt å forhindre en persons handlinger eller aktiviteter før negative helseeffekter oppstår. Forebyggingstiltak kan utformes og tilpasses en bestemt målgruppe eller gjøres universelle i et forsøk på å nå flest mulig. Tiltakene kan nå enkeltpersoner, grupper eller hele samfunnet ved hjelp av ulike tilnærminger, som for eksempel regelverk (lover), kampanjer i massemedia, en-til-en samtaler, gruppearbeid, undervisning i skoler, i helsetjenesten eller ved hjelp av elektroniske ressurser. Tobakk har lenge vært et fokus for primærforebyggende tiltak. Røykens påvirkninger på helsemessige utfall, som for eksempel på kreft er velkjente. Tobakk er også svært vanedannende. Siden god helse og trivsel i barndommen er en ressurs for fremtidig helse, er det viktig å fokusere på helsefremmende og forebyggende tiltak for barn og unge. I Norge er det fortsatt et betydelig, men avtagende antall ungdommer som røyker. Primærforebyggende tiltak rettet mot denne aldersgruppen er en måte å motvirke bruk av tobakksprodukter hos barn og unge. Den mest hensiktsmessige måten å nå et stort antall barn og unge på samtidig er å gjennomføre tiltak på skolen eller i forbindelse med kontakt med primærhelsetjenesten, dvs i små sosiale miljøer. For å rette forebyggingsarbeidet blant barn og unge mot områder og tiltak som har dokumentert effekt, er det viktig å få en oversikt over effekten av ulike primærforebyggende tiltak. 
Mål Formålet med denne oversikten over systematiske oversikter er å oppsummere og presentere eksisterende systematiske oversikter om effekten av primærforebyggende tiltak, gitt i små sosiale miljøer, mot tobakk hos barn og unge. 

**Metode** 
Vi utførte en oversikt over systematiske oversikter. Det er en oppdatering av en oversikt vi publiserte i 2012. Vi inkluderte derfor systematiske oversikter som var publisert i 2012 eller senere, og som vurderer effekten av primærforebyggende tiltak mot tobakk hos barn og unge, gitt i små sosiale miljøer som skoler og primærhelsetjenesten (forebygge betyr her det samme som å forhindre eller hindre). Oversiktene kunne omfatte studier med populasjoner av barn eller unge i alderen 19 år eller yngre. Vi søkte i ti elektroniske litteraturdatabaser i april 2018. To forskere vurderte titler og abstrakter, og tok den endelige beslutningen om inkludering basert på vurdering av relevante fulltekster. Vi vurderte den metodiske kvaliteten til relevante oversikter, og inkluderte kun de som hadde høy metodisk kvalitet. Vi trakk ut forfatternes resultater og, hvis tilgjengelig, deres vurdering av tillit til effektestimatene for hvert utfall ved hjelp av GRADEmetoden. Dersom forfatterne ikke hadde gjort en GRADE-vurdering, brukte vi tilgjengelige data til å gjøre en egen vurdering. Ved hjelp av GRADE uttrykker vi vår tillit til at den estimerte effekten ligger nær den forventede effekten av tiltaket (den &quot;sanne&quot; effekten) som høy, middels, lav eller svært lav for hvert utfall. 

**Resultat** 
To forskere vurderte 5761 titler og abstrakter, og 179 fulltekster. Vi vurderte den metodiske kvaliteten til de 14 systematiske oversiktene som vurderte effekten av primærforebyggende tiltak mot tobakk blant barn og unge i alderen 19 år og yngre. Av disse inkluderte vi syv systematiske oversikter (med 195 primærstudier) som alle hadde høy metodisk kvalitet. Fem av oversiktene undersøkte tiltak som ble gitt på skolen (dvs. skolebaserte tiltak). To oversikter undersøkte tiltak som ble gitt i, eller var relevante for, primærhelsetjenesten. Flertallet av primærstudiene som var inkludert i disse oversiktene var utført i Nord-Amerika, Europa og Australia. Flertallet av de totalt ca 500,000 deltakerne var i alderen 12-19 år. Fem systematiske oversikter undersøkte primærforebyggende tiltak som ble levert på skolen. Tiltak basert på insentiver, som for eksempel røykfri-klasse konkurranser, og universelle resiliens-baserte tiltak (resiliens=evnen til å håndtere stress og katastrofer) hadde ingen signifikant effekt på om barn og unge begynte å røyke. Det var heller ingen funn som tydet på at kjønnsnøytrale skolebaserte forebyggingstiltak mot røyking hadde en effekt på å hindre at tenåringsjenter røyker. Derimot var generelle skolebaserte opplæringstiltak effektive ved langtidsoppfølging (dvs, effekten var målt ett år eller lengre etter at tiltaket ble satt i gang). Varte tiltakene ett år eller mindre var de kun effektive i kombinasjon med tiltak som fokuserte på sosial kompetanse/sosial påvirkning. Også opplæringstiltak som fokuserte på sosial kompetanse og de som kombinerte sosial kompetanse og sosial påvirkning var effektive ved langtidsoppfølging. I subgruppeanalyser fant forskerne at ved langtidsoppfølging var tiltak ledet av voksne, med fokus kun på tobakk og med tilleggs-samlinger (&laquo;booster sessions&raquo;) effektive. De to systematiske oversiktene som undersøkte effekten av tiltak gitt i, eller var relevante for, primærhelsetjenesten viste at tiltakene trolig var effektive, med en gjennomsnittlig risk reduksjon for røyking på 18 % og 19 %. Antallet som må få tiltaket for at det skal være effekt hos &eacute;n person (&laquo;numbers needed to treat&raquo;) var ca. 50. Tiltakene som var omtalt i disse to systematiske oversiktene var svært varierte. Forskerne konkluderte med at de mest effektive tiltakene var skreddersydde i forhold til forebygging, fokuserte bare på tobakk, var rettet mot enkeltindividet, varte i minst 12 måneder og inkluderte opplæring/ informasjonskomponenter. 

**Diskusjon** 
I denne oversikten inkluderte vi kun resultater fra systematiske oversikter av høy metodisk kvalitet. Det er imidlertid viktig å merke seg at selv om en systematisk oversikt er metodisk godt utført, så kan de inkluderte primærstudiene være av varierende metodisk kvalitet. I denne oversikten hadde vi stort sett middels tillit i resultatene, noe som betyr at den &lsquo;sanne&rsquo; effekten av tiltakene sannsynligvis vil være nær estimatet av effekten vi rapporterer, men det er en mulighet for at det er vesentlig forskjellig. Sammen med vår tidligere oversikt over systematiske oversikter, utgitt i 2012, gir denne oversikten en detaljert beskrivelse av effektene av primærforebyggende tiltak mot tobakk hos barn og unge over en svært lang periode. Kontekstene for denne oversikten er svært varierte, med studier som er utført i mange ulike geografiske områder. Flertallet av de inkluderte primærstudiene er imidlertid gjennomført i Europa, Nord-Amerika og Australia. I tillegg er studiepopulasjonen, barn og unge, i disse landene på samme alder. Det er likevel viktig å merke seg at røyking har ulike kulturelle, juridiske og sosiale betydninger i ulike kontekster. Disse kan være forskjellige fra hvordan røyking oppfattes av barn og unge i Norge. Basert på funnene i denne oversikten over systematiske oversikter kan eksisterende primærforebyggende tiltak undersøkes for å se om de bruker de mest effektive teoriog tiltakskomponentene. Våre funn tyder på at de tiltakene som er mest effektiv er de som fokuserer på sosial kompetanse kombinert med sosial påvirkning, fokuserer kun på tobakk, er gitt av en voksen og har tilleggs-samlinger (&laquo;booster-sessions&raquo;). Det er viktig å merke seg at ingen av tiltakene fokuserte direkte på snus eller elektroniske sigaretter, så vi kan ikke si noe om effekten på det. Det var også få tiltak som var gitt via digitale plattformer, noe som blir stadig mer vanlig pga. at befolkningen har økt tilgang til internett og smarttelefoner. Det er nødvendig med mer forskning om hvilke tiltakskomponenter, tidspunkt for implementering, leveringsmekanismer og intensitet som er mest effektive. Det er også nødvendig med bedre rapportering av disse elementene i primærstudier. Gitt det økende antallet unge som begynner å bruke snus i Norge bør fremtidig forskning undersøke om eksisterende tiltak er effektive for å hindre bruk av snus eller om nye tiltak må utvikles. 

**Konklusjon** 
Primærforebyggende tiltak mot tobakk som gis i små sosiale miljøer &ndash; både de som gis på skolen og i primærhelsetjenesten &ndash; ser ut til å være effektive i å hindre at barn og unge begynner å røyke. Tiltak som ser ut til å være mest effektive er skolebaserte tiltak som kombinerer opplæring i sosial påvirkning og sosial kompetanse, eller inkluderer en komponent om sosial kompetanse, fokuserer kun på tobakk, er ledet av en voksen og har tilleggs-samlinger.
AU  - Ames,
AU  - H.
AU  - Langøien,
AU  - L.
AU  - J.
AU  - Berg,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /publ/2019/hvor-effektive-er-primarforebyggende-tiltak-mot-bruk-av-tobakk-hos-barn-og-/
PY  - 2019
T2  - Folkehelseinstituttet
TI  - Hvor effektive er primærforebyggende tiltak mot bruk av tobakk hos barn og unge? En oversikt over systematiske oversikter
ER  -
TY  - JOUR
AB  - **Background:** 
Self-harm and suicide in children and adolescents are of serious consequence and increase during the adolescent years. Consequently, there is need for interventions that prevent such behaviour. 

**The objective of this paper:** 
to evaluate the effects of interventions preventing self-harm and suicide in children and adolescents in an overview of systematic reviews. 

**Method(s):** 
We conducted a review of systematic reviews (OoO). We included reviews evaluating any preventive or therapeutic intervention. The quality of the included reviews was assessed independently, and data was extracted by two reviewers. We report the review findings descriptively. The certainty of the evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE). 

**Result(s):** 
Moderate certainty evidence suggests that school-based interventions prevent suicidal ideation and attempts short term, and possibly with long term effects on suicide attempts. The effects of community-based interventions following suicide clusters and local suicide plans are uncertain, as are the benefits and harms of screening young people for suicide risk. The effects of most interventions targeting children and adolescents with known self-harm are uncertain. However, low certainty evidence suggests that dialectical behavioural therapy and developmental group therapy are equally as effective on repetition of self-harm as enhanced treatment as usual. 

**Conclusion(s):** 
Research on several recommended practices, such as local suicide plans, prevention of suicide clusters and approaches to risk assessment, is lacking. When implemented, these interventions should be closely evaluated. There also is need for more research on treatment for repeated self-harm, including long term follow-up, and in general: possible harmful effects. Policy makers and health providers should consider evidence from population-based studies and adults in preventing self-harm and suicide in children and adolescents. Also, approaches showing promise in treatment of conditions associated with self-harm and/or suicidality, such as depression and psychosis, should be considered. 

PROSPERO registration: CRD42019117942 08/02/19.
AD  - (Morken, Dahlgren) Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway (RBUP), Oslo, Oslo 0484, Norway (Lunde, Toven) Regional Centre on violence, trauma and suicide prevention, Eastern Norway, Oslo 0484, NorwayI.S. Morken, Regional Centre for Child and Adolescent Mental Health, Eastern and Southern Norway (RBUP), Oslo, Oslo 0484, Norway. E-mail: ida.sund.morken@gmail.com
AN  - 2003259697
AU  - Morken,
AU  - I.
AU  - S.
AU  - Dahlgren,
AU  - A.
AU  - Lunde,
AU  - I.
AU  - Toven,
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.12688/F1000RESEARCH.19506.1
DP  - Ovid Technologies
KW  - Adolescents
KW  - Children
KW  - Evidence-based practice
KW  - Mental health
KW  - Prevention
KW  - Self-harm
KW  - Suicide
KW  - Treatment
KW  - adolescent
KW  - adult
KW  - automutilation
KW  - child
KW  - dialectical behavior therapy
KW  - female
KW  - follow up
KW  - group therapy
KW  - human
KW  - male
KW  - peer review
KW  - psychosis
KW  - review
KW  - risk assessment
KW  - suicidal ideation
KW  - suicide attempt
KW  - systematic review
L1  - internal-pdf://3415453446/Morken-2019-The effects of interventions preve.pdf
LA  - English
M3  - Review
PY  - 2019
T2  - F1000Research
TI  - The effects of interventions preventing self-harm and suicide in children and adolescents: An overview of systematic reviews [version 1; peer review: 1 approved]
UR  - http://f1000research.com/articles?tab=ALL&amp;articleType=&amp;subjectArea=&amp;subtopic=&amp;show=50
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2003259697
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.12688%2FF1000RESEARCH.19506.1&amp;issn=2046-1402&amp;isbn=&amp;volume=8&amp;issue=&amp;spage=890&amp;pages=&amp;date=2019&amp;title=F1000Research&amp;atitle=The+effects+of+interventions+preventing+self-harm+and+suicide+in+children+and+adolescents%3A+An+overview+of+systematic+reviews+%5Bversion+1%3B+peer+review%3A+1+approved%5D&amp;aulast=Morken&amp;pid=%3Cauthor%3EMorken+I.S.%3C%2Fauthor%3E%3CAN%3E2003259697%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://f1000researchdata.s3.amazonaws.com/manuscripts/21386/8acbe2e3-d16a-4b7b-b441-c8e568d09a9d_19506_-_ida_sund_morken.pdf?doi=10.12688/f1000research.19506.1&amp;numberOfBrowsableCollections=19&amp;numberOfBrowsableInstitutionalCollections=5&amp;numberOfBrowsableGateways=22
VL  - 8 (no pagination)
ER  -
TY  - JOUR
AB  - To update a comparative effectiveness review (1980-2011) of treatments for adolescents whose depressive episode or disorder (MDE/MDD) did not respond to one or more trials of SSRI antidepressants. MEDLINE, Cochrane Central, PsychINFO, Cochrane Database of Systematic Reviews, EMBASE, CINAHL, and AMED were searched in addition to the grey literature. We spanned May 2011 to September 1, 2017 and included only articles in English. 11 new studies were reviewed based on the criteria of having tested a comparative treatment in adolescents with MDD or MDE who were confirmed to have failed one or more SSRI trials. Data were extracted using standardized forms and a reference guide in DistillerSR; a second reviewer verified the accuracy of the data fields and discrepancies were resolved by consensus. One trial (N = 29) found a small benefit of escalating doses of fluoxetine and the treatment of adolescent depression study (TORDIA, N = 334) found significant benefits of combined SSRI or venlafaxine treatment with CBT for most outcomes. No new studies were identified since the previous review (2012). One trial is currently registered that will be a cross over trial of rTMS; other registered trials are open label. Multiple secondary data analyses of TORDIA have identified important predictors of treatment response and relapse. No new comparative studies were identified since the original review. Trials are desperately needed to identify new treatments for youth with SSRI resistant MDD. These youth should not be deemed as treatment resistant until completing one or two failed trials of SSRI combined with evidence-based psychotherapy.
AN  - 31165921
AU  - Boylan,
AU  - K.
AU  - MacQueen,
AU  - G.
AU  - Kirkpatrick,
AU  - R.
AU  - Lee,
AU  - J.
AU  - Santaguida,
AU  - P.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00787-019-01341-5
L1  - internal-pdf://2743507521/Boylan-2019-A systematic review of interventio.pdf
PY  - 2019
SP  - 05
T2  - European Child &amp; Adolescent Psychiatry
TI  - A systematic review of interventions for treatment resistant major depressive disorder in adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31165921
UR  - https://link.springer.com/article/10.1007%2Fs00787-019-01341-5
VL  - 05
ER  -
TY  - JOUR
AB  - **Background and objectives:** 
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common psychiatric disorders in children and adolescents. Mind&ndash;body therapies (MBTs) seem to be effective for improving health in different populations; however, whether a positive effect occurs in children and adolescents with ADHD is still controversial. The main aim of this systematic review was to analyse the interventions based on MBT aimed to improve the main ADHD symptoms in children and adolescents. 

**Materials and Methods:** 
A systematic review was conducted following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines to identify MBT studies on children and adolescents (4&ndash;18 years) with a clinical diagnosis of ADHD. Study quality was evaluated by the NIH quality tool (U.S. National Institute of Health). 

**Results:** 
There were positive results in eleven out of twelve included studies regarding the effect of the MBT interventions on ADHD symptoms. With respect to ADHD symptoms, we observed differences across studies. In relation to the studies&rsquo; quality, eleven studies were rated &ldquo;poor&rdquo; and one was rated as &ldquo;fair&rdquo;. 

**Conclusions:** 
MBTs, such as yoga or mindfulness, could be positive strategies to mitigate ADHD symptoms in children and adolescents. However, further research with high-quality designs, with randomization, greater sample sizes, and more intensive supervised practice programs are needed.
AN  - 31262094
AU  - Barranco-Ruiz,
AU  - Y.
AU  - Etxabe,
AU  - B.
AU  - E.
AU  - Ramirez-Velez,
AU  - R.
AU  - Villa-Gonzalez,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3390/medicina55070325
L1  - internal-pdf://4244956130/Barranco-Ruiz-2019-Interventions Based on Mind.pdf
PY  - 2019
SP  - 30
TI  - Interventions Based on Mind-Body Therapies for the Improvement of Attention-Deficit/Hyperactivity Disorder Symptoms in Youth: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31262094
UR  - https://res.mdpi.com/medicina/medicina-55-00325/article_deploy/medicina-55-00325-v2.pdf?filename=&amp;attachment=1
VL  - 55
ER  -
TY  - JOUR
AB  - **Background**
Motivational Interviewing (MI) is a directive patient‐centred style of counselling, designed to help people to explore and resolve ambivalence about behaviour change. It was developed as a treatment for alcohol abuse, but may help people to a make a successful attempt to stop smoking.

**Objectives**
To evaluate the efficacy of MI for smoking cessation compared with no treatment, in addition to another form of smoking cessation treatment, and compared with other types of smoking cessation treatment. We also investigated whether more intensive MI is more effective than less intensive MI for smoking cessation.

**Search methods**
We searched the Cochrane Tobacco Addiction Group Specialised Register for studies using the term motivat* NEAR2 (interview* OR enhanc* OR session* OR counsel* OR practi* OR behav*) in the title or abstract, or motivation* as a keyword. We also searched trial registries to identify unpublished studies. Date of the most recent search: August 2018.

**Selection criteria**
Randomised controlled trials in which MI or its variants were offered to smokers to assist smoking cessation. We excluded trials that did not assess cessation as an outcome, with follow‐up less than six months, and with additional non‐MI intervention components not matched between arms. We excluded trials in pregnant women as these are covered elsewhere.

**Data collection and analysis**
We followed standard Cochrane methods. Smoking cessation was measured after at least six months, using the most rigorous definition available, on an intention‐to‐treat basis. We calculated risk ratios (RR) and 95% confidence intervals (CI) for smoking cessation for each study, where possible. We grouped eligible studies according to the type of comparison. We carried out meta‐analyses where appropriate, using Mantel‐Haenszel random‐effects models. We extracted data on mental health outcomes and quality of life and summarised these narratively.

**Main results**
We identified 37 eligible studies involving over 15,000 participants who smoked tobacco. The majority of studies recruited participants with particular characteristics, often from groups of people who are less likely to seek support to stop smoking than the general population. Although a few studies recruited participants who intended to stop smoking soon or had no intentions to quit, most recruited a population without regard to their intention to quit. MI was conducted in one to 12 sessions, with the total duration of MI ranging from five to 315 minutes across studies. We judged four of the 37 studies to be at low risk of bias, and 11 to be at high risk, but restricting the analysis only to those studies at low or unclear risk did not significantly alter results, apart from in one case ‐ our analysis comparing higher to lower intensity MI.

We found low‐certainty evidence, limited by risk of bias and imprecision, comparing the effect of MI to no treatment for smoking cessation (RR = 0.84, 95% CI 0.63 to 1.12; I2 = 0%; adjusted N = 684). One study was excluded from this analysis as the participants recruited (incarcerated men) were not comparable to the other participants included in the analysis, resulting in substantial statistical heterogeneity when all studies were pooled (I2 = 87%). Enhancing existing smoking cessation support with additional MI, compared with existing support alone, gave an RR of 1.07 (95% CI 0.85 to 1.36; adjusted N = 4167; I2 = 47%), and MI compared with other forms of smoking cessation support gave an RR of 1.24 (95% CI 0.91 to 1.69; I2 = 54%; N = 5192). We judged both of these estimates to be of low certainty due to heterogeneity and imprecision. Low‐certainty evidence detected a benefit of higher intensity MI when compared with lower intensity MI (RR 1.23, 95% CI 1.11 to 1.37; adjusted N = 5620; I2 = 0%). The evidence was limited because three of the five studies in this comparison were at risk of bias. Excluding them gave an RR of 1.00 (95% CI 0.65 to 1.54; I2 = n/a; N = 482), changing the interpretation of the results.

Mental health and quality of life outcomes were reported in only one study, providing little evidence on whether MI improves mental well‐being.

**Authors&#039; conclusions**
There is insufficient evidence to show whether or not MI helps people to stop smoking compared with no intervention, as an addition to other types of behavioural support for smoking cessation, or compared with other types of behavioural support for smoking cessation. It is also unclear whether more intensive MI is more effective than less intensive MI. All estimates of treatment effect were of low certainty because of concerns about bias in the trials, imprecision and inconsistency. Consequently, future trials are likely to change these conclusions. There is almost no evidence on whether MI for smoking cessation improves mental well‐being.
AN  - CD006936
AU  - Lindson,
AU  - N.
AU  - Thompson,
AU  - T.
AU  - P.
AU  - Ferrey,
AU  - A.
AU  - Lambert,
AU  - J.
AU  - D.
AU  - Aveyard,
AU  - P.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD006936.pub4
KW  - Behavior Therapy [*methods]
KW  - Hotlines
KW  - Humans
KW  - Motivation
KW  - Motivational Interviewing [*methods]
KW  - Randomized Controlled Trials as Topic
KW  - Smoking Cessation [psychology]
KW  - Smoking [*psychology, *therapy]
L1  - internal-pdf://4246288323/Lindson_et_al-2019-Cochrane_Database_of_System.pdf
N1  - [Tobacco Addiction]
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Motivational interviewing for smoking cessation
UR  - https://doi.org//10.1002/14651858.CD006936.pub4
ER  -
TY  - JOUR
AB  - **AIM: **
To determine the effectiveness of technological-based educational interventions on the empowerment-related outcomes of children and young adults with cancer. 

**DESIGN: **
Quantitative systematic review. 

**DATA SOURCES: **
Six electronic databases, including PubMed, Cochrane Library, EMBASE, CINAHL, Scopus, and PsycINFO, were searched to identify eligible randomized controlled trials from each database&#039;s point of inception to December 2017. Grey literature was also searched from ProQuest and MedNar. 

**REVIEW METHODS:**
A narrative summary of the results was undertaken owing to the small number of eligible studies and high heterogeneity across the studies. 

**RESULTS: **
Five studies were included in the review. Five empowerment-related outcomes under the domain &quot;patient states&quot; were identified at differing time points of 3-month postintervention, immediate postintervention, and during treatment: (a) self-efficacy; (b) cancer knowledge; (c) health locus of control; (d) emotional well-being; and (e) quality of life. At 3-month postintervention, health locus of control was found to be significant in two studies and self-efficacy and cancer knowledge were found to be significant in one study. No difference in quality of life was found. At immediate postintervention, a beneficial indication was observed. During treatment, no statistical significance was found regarding the effectiveness of a technological-based cognitive behavioural package. 

**CONCLUSION: **
Weak evidences led to inconclusive findings on the effectiveness of technological-based educational interventions on the empowerment-related outcomes of children and young adults with cancer. Future research will benefit from well-designed clinical trials that use a common outcome measurement to provide more information regarding the effectiveness of such interventions.
AN  - 30740758
AU  - Lim,
AU  - N.
AU  - L.
AU  - Y.
AU  - Shorey,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jan.13974
L1  - internal-pdf://3563177734/Lim-2019-Effectiveness of technology-based edu.pdf
PY  - 2019
SP  - 11
T2  - Journal of Advanced Nursing
TI  - Effectiveness of technology-based educational interventions on the empowerment related outcomes of children and young adults with cancer: A quantitative systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30740758
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/jan.13974
VL  - 11
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Guidelines for maintenance treatment of juvenile bipolar disorder (jBD) rely heavily on evidence from adult studies and relatively brief trials in juveniles, leaving uncertainties about optimal long-term treatment. We aimed to systematically review long-term treatment trials for jBD. 

**METHODS:** 
We analyzed data recovered by systematic literature searching using PRISMA guidelines statement, through 2018, for peer-reviewed reports on pharmacological treatments for jBD lasting &gt;=24-weeks. 

**RESULTS:** 
Of 13 reports with 16 trials of 9 treatments, 18.8% were randomized-controlled [RCTs]) with 1773 subjects (94.4% BD-I; ages 6.9-15.1 years), lasting 11.7 (6-22) months. Pooled clinical response rates were 66.8% [CI: 64.4-69.1] with drugs vs. 60.6% [53.0-66.7] in 3 placebo-control arms. Random-effects meta-analysis of 4 controlled trials yielded pooled OR=2.88 ([0.87-9.60], p=0.08) for clinical response, and OR=7.14 ([1.12-45.6], p=0.04) for nonrecurrence. Apparent efficacy ranked: combined agents &gt; anticonvulsants &gt;= lithium &gt;= antipsychotics. Factors favoring response ranked: more ADHD, polytherapy, RCT design, nonrecurrence vs. response. Adverse-events (incidence, 5.50%-28.5%), notably included cognitive dulling, weight-gain, and gastrointestinal symptoms; early dropout rates averaged 49.8%. 

**CONCLUSIONS:** 
Pharmacological treatments, including anticonvulsants, lithium, and second-generation antipsychotics may reduce long-term morbidity in jBD. However, study number, quality, and effect-magnitude were limited, leaving scientific support for maintenance treatment for jBD inconclusive.
AN  - 31211354
AU  - Yee,
AU  - C.
AU  - S.
AU  - Hawken,
AU  - E.
AU  - R.
AU  - Baldessarini,
AU  - R.
AU  - J.
AU  - Vazquez,
AU  - G.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1093/ijnp/pyz034
L1  - internal-pdf://3043142254/Yee-2019-Maintenance Pharmacological Treatment.pdf
PY  - 2019
SP  - 17
T2  - International Journal of Neuropsychopharmacology
TI  - Maintenance Pharmacological Treatment of Juvenile Bipolar Disorder: Review and Meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31211354
UR  - https://watermark.silverchair.com/pyz034.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAlEwggJNBgkqhkiG9w0BBwagggI-MIICOgIBADCCAjMGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMe7gpgbV7LqYSS-8uAgEQgIICBKwAO7ggpZOjt5bStqhUvnvwkYVyKPzbdeE5xOnSvym6t1qAiJ1qv60YE0PymWoO_0jSXfvnMDM1UohMntlnHs55-essVXfDsurK1NCFrHfVnXteCWnMOwHrBWJDwVwgnGt3FFCqP5V3zg_gd7A_fu9H48sTOFZZhNyRbuAyw2Qb8FyBjK9jdiRXZ_2jD67fZtQmc_Pm8gRsal8CdYATzFRT9_EJqwN1nHFGxyG3-7FgEVUUiKD5oKXTsLVudjHZeqPSZNjuu1XaiDDAeIJYtXrojpZ66GaavnvOkPqlKhjMjZQROxJZcjiSzRdb4qHj4vwxLdR9PB4GhzEkLFu8hMdaaVe5VzwHnkgETTJ7UI5GNPpx9VfmSgXdTHReNMKQzG1lK3UsrIWTkfL0sO5-lS8aaL-8XvwwiwCvveS3GxR7ugHYjpaCFKOyqO0LDA4AWYUEzGd-2RwSmuUN4s-huGNo7NGe1ZKwyAYjbuBgdtTcDdWqsWsAuXedOtfCeOlgjthuSX-zRjmDUeCIY7ok6rRBRRQSOv6KW0ZrQBf4LwRuLTcCO5m0QXz9VNLoaKxecu1_4zf477Y5NPZmeBHIWlHkXpLzsGEhcj1DzC5s_5hl9okjDP7CqVwvy6mvZjZO6pJfB8sC8i_Ogbnfmu59AcmjrDzbBrp-1EgOuIIAYAtyVCI41w
VL  - 17
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Aripiprazole is widely used in the management of tic disorders (TDs), we aimed to assess the safety of aripiprazole for TDs in children and adolescents. 

**METHODS:** 
A systematic literature review was performed in the databases of MEDLINE, Embase, the Cochrane Library and 4 Chinese databases, from inception to February 2019. All types of studies evaluating the safety of aripiprazole for TDs were included. The quality of studies was assessed using the Cochrane Risk of Bias tool, the Newcastle-Ottawa Scale tool, the National Institute of Clinical Excellence, the CARE (Case Report) guidelines according to types of studies. Risk ratio (RR) and incidence rate with a 95% confidence interval (CI) were used to summarize the results. 

**RESULTS:** 
A total 50 studies involving 2604 children met the inclusion criteria. The result of meta-analysis of randomized controlled trials showed that there was a significant difference between aripiprazole and haloperidol with respect to rate of somnolence (RR = 0.596, 95% CI: 0.394, 0.901), extrapyramidal symptoms (RR = 0.236, 95% CI: 0.111, 0.505), tremor (RR = 0.255, 95% CI: 0.114, 0.571), constipation (RR = 0.148, 95% CI: 0.040, 0.553), and dry mouth (RR = 0.141, 95% CI: 0.046, 0.425). There was a significant difference between aripiprazole and placebo in the incidence rate of adverse events (AEs) for somnolence (RR = 6.565, 95% CI: 1.270, 33.945). The meta-analysis of incidence of AEs related to aripiprazole for case series studies revealed that the incidence of sedation was 26.9% (95% CI: 16.3%, 44.4%), irritability 25% (95% CI: 9.4%, 66.6%), restlessness 31.3% (95% CI: 13%, 75.1%), nausea and vomiting 28.9% (95% CI: 21.1%, 39.5%), and weight gain 31.3% (95% CI: 10.7%, 91.3%). 

**CONCLUSION:** 
Aripiprazole was generally well tolerated in children and adolescents. Common AEs were somnolence, headache, sedation, nausea, and vomiting. Further high-quality studies are needed to confirm the safety of aripiprazole for children and adolescents with TDs.
AN  - 31145316
AU  - Yang,
AU  - C.
AU  - Yi,
AU  - Q.
AU  - Zhang,
AU  - L.
AU  - Cui,
AU  - H.
AU  - Mao,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/MD.0000000000015816
L1  - internal-pdf://2489625026/Yang-2019-Safety of aripiprazole for tics in c.pdf
PY  - 2019
SP  - e15816
T2  - Medicine
TI  - Safety of aripiprazole for tics in children and adolescents: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=31145316
VL  - 98
ER  -
TY  - JOUR
AB  - **AIM:** 
To evaluate the effects of family-centred care on hospitalized preterm infants.

**BACKGROUND:** 
With an increase in published reports on family-centred care for preterm infants, there is a need for an up-to-date review and meta-analysis of rigorously designed studies to measure the effects of family-centred care on preterm infants.DESIGN: A systematic review and meta-analysis.

**DATA SOURCES:** 
The Cochrane Library (Issue 12, 2017), PubMed (1966 to December 2017), CINAHL (1982 to December 2017), EMBASE (1974 to December 2017), and Web of Science (1975 to December 2017) databases were searched.

**REVIEW METHODS:** 
Relevant terms were used to search for randomized controlled trials of family-centred care versus standard care. A modified rating scale was utilized to assess studies for the degree of family-centredness of the intervention.

**RESULTS:** 
Four studies involving 1026 preterm infants were included. Compared with standard care, family-centred care shortened the total length of hospital stay and length of neonatal intensive care unit stay. There was inadequate evidence to demonstrate any effects of family-centred care on infant morbidity, feeding, growth, or neurobehavioural performance.

**CONCLUSION:**
Family-centred care is an effective and safe intervention to shorten the length of stay in the hospital and improve survival quality among hospitalized preterm infants.
AD  - Yu, Xiaoyan. School of Health Sciences, Wuhan University, Wuhan, China.Zhang, Jun. School of Health Sciences, Wuhan University, Wuhan, China.
AN  - 30378217
AU  - Yu,
AU  - X.
AU  - Zhang,
AU  - J.
DA  - Jun
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/ijn.12705
DP  - Ovid Technologies
J2  - Int J Nurs Pract
KW  - *Family
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - *Infant, Premature
KW  - Intensive Care Units, Neonatal
KW  - Length of Stay
KW  - *Patient-Centered Care
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://1546841069/Yu_et_al-2019-International_Journal_of_Nursing.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Yu, XiaoyanZhang, Jun
PY  - 2019
SP  - e12705
T2  - International Journal of Nursing Practice
TI  - Family-centred care for hospitalized preterm infants: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=30378217
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/ijn.12705
VL  - 25
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** 
To summarize the current evidence on the effects and safety of massage therapy for the treatment of ADHD in children and adolescents. 

**METHOD:** 
A systematic review of 8 randomized controlled trials (RCTs) and 3 case series studies was conducted with a meta-analysis of 4 of the RCTs. 

**RESULTS:** 
Pooled analysis showed that massage produced more improvement in ADHD symptoms in terms of effective rate compared to Ritalin (risk ratio: 1.39, 95%CI: 1.16-1.66; P=0.0004). Individual RCTs suggested that massage was differed significantly from waitlist control in improving the conditions of anxious-passive (mean difference: -11.7; 95%CI [-17.84, -5.56]; P=0.0002), and asocial behavior (mean difference=-8.60; 95%CI [-15.87, -1.33]; P=0.02). 

**CONCLUSION:** 
Evidence suggests that massage therapy is beneficial for treating ADHD in children and adolescents.
AN  - 30670272
AU  - Chen,
AU  - S.
AU  - C.
AU  - Yu,
AU  - B.
AU  - Y.
AU  - Suen,
AU  - L.
AU  - K.
AU  - Yu,
AU  - J.
AU  - Ho,
AU  - F.
AU  - Y.
AU  - Yang,
AU  - J.
AU  - J.
AU  - Yeung,
AU  - W.
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ctim.2018.12.011
L1  - internal-pdf://2527242930/Chen-2019-Massage therapy for the treatment of.pdf
PY  - 2019
SP  - 389-399
T2  - Complementary Therapies in Medicine
TI  - Massage therapy for the treatment of attention deficit/hyperactivity disorder (ADHD) in children and adolescents: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30670272
UR  - https://ac.els-cdn.com/S0965229918309154/1-s2.0-S0965229918309154-main.pdf?_tid=c7b309e1-b8fe-4554-b0f5-f25e46188a1a&amp;acdnat=1549447265_f346cf9b77f5bc002a7936b3c544ea1c
VL  - 42
ER  -
TY  - JOUR
AB  - The importance of social studies and civics education is increasing, as evidenced by the growing number of states requiring coursework in this area for graduation and its growing presence in school accountability frameworks. Social studies instruction is critical for all students so that they may understand their roles, rights, and responsibilities as citizens and how their actions can influence their communities. 

Students who exhibit antisocial behaviors, such as those with emotional and behavioral disorders (EBD), may especially benefit from social studies and civics education as it promotes college and career readiness and provides opportunities to engage in social problem solving and perspective taking. 

The purpose of this study was to systematically review the social studies and civics intervention research for students with EBD. We sought to describe and evaluate the extant literature, identify promising practices, and suggest areas for future research. A total of 17 intervention studies were identified.

 Overall, 10 out of the 17 studies met What Works Clearinghouse Design Standards with or without reservations. Eight of the 10 studies were eligible for effect size calculation, resulting in an overall large effect ( g = 0.83). Study limitations, implications for school practice, and directions for research are discussed.
AN  - 30854879
AU  - Garwood,
AU  - J.
AU  - D.
AU  - McKenna,
AU  - J.
AU  - W.
AU  - Roberts,
AU  - G.
AU  - J.
AU  - Ciullo,
AU  - S.
AU  - Shin,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0145445519834622
L1  - internal-pdf://2411906510/Garwood-2019-Social Studies Content Knowledge.pdf
PY  - 2019
SP  - 145445519834622
T2  - Behavior Modification
TI  - Social Studies Content Knowledge Interventions for Students With Emotional and Behavioral Disorders: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30854879
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Obsessive-compulsive disorder (OCD) is a chronic mental health disorder characterized by recurring obsessions and compulsions affecting 1-3% of children and adolescents. Current treatment options are limited by accessibility, availability, and quality of care. New technologies provide opportunities to address at least some of these challenges. This paper aims to investigate the acceptability, feasibility, and efficacy of traditional cognitive behavioral therapy with Internet cognitive behavioral therapy (iCBT) for pediatric OCD according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

**METHOD:** 
We searched EMBASE, Medline, PsycINFO, CENTRAL, LILACS, CINAHL, and Scopus. Results include articles from 1987 to March 2018. Main inclusion criteria were patients aged 4-18, primary diagnosis of OCD, and iCBT.

**RESULTS:** 
Of the 2323 unique articles identified during the initial search, six studies with a total of 96 participants met our inclusion criteria: three randomized controlled trials, one single-case multiple-baseline design, one open-label trial, and one case series. Four studies reported a significant decrease in OCD severity on the Children&#039;s Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) following iCBT, one study reported significant decrease in CY-BOCS scores for iCBT relative to waitlist, and the case series reported (some) symptom reduction in all participants. Six studies reported high rates of feasibility, and five studies reported good acceptability of iCBT.

**CONCLUSION:** 
At present, evidence regarding acceptability, feasibility, and efficacy of iCBT for pediatric OCD is limited. Results are promising but need to be confirmed and refined in further research.Systematic review registration: Prospero crd4201808587.
AD  - Babiano-Espinosa, Lucia. Department of Mental Health, Regional Centre for Child and Youth Mental Health and Child Welfare (RKBU), Norwegian University of Science and Technology (NTNU), Trondheim, Norway. Lucia.babiano-espinosa@ntnu.no.Wolters, Lidewij H. Department of Mental Health, Regional Centre for Child and Youth Mental Health and Child Welfare (RKBU), Norwegian University of Science and Technology (NTNU), Trondheim, Norway.Wolters, Lidewij H. De Bascule, Academic Center for Child and Adolescent Psychiatry, Center of Expertise for OCD, Anxiety and Tics, Meibergdreef 5, 1105, AZ, Amsterdam, The Netherlands.Weidle, Bernhard. Department of Mental Health, Regional Centre for Child and Youth Mental Health and Child Welfare (RKBU), Norwegian University of Science and Technology (NTNU), Trondheim, Norway.Op de Beek, Vivian. Department of Mental Health, Regional Centre for Child and Youth Mental Health and Child Welfare (RKBU), Norwegian University of Science and Technology (NTNU), Trondheim, Norway.Pedersen, Sindre A. Health, Library Section for Medicine and Health Sciences, Norwegian University of Science and Technology, Olav Kyrres gate 9, 7030, Trondheim, Norway.Compton, Scott. Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, 2200 W Main St #340, Durham, NC, 27705, USA.Skokauskas, Norbert. Department of Mental Health, Regional Centre for Child and Youth Mental Health and Child Welfare (RKBU), Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
AN  - 31747935
AU  - Babiano-Espinosa,
AU  - L.
AU  - Wolters,
AU  - L.
AU  - H.
AU  - Weidle,
AU  - B.
AU  - Op
AU  - de
AU  - Beek,
AU  - V.
AU  - Pedersen,
AU  - S.
AU  - A.
AU  - Compton,
AU  - S.
AU  - Skokauskas,
AU  - N.
DA  - Nov 20
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s13643-019-1166-6
DP  - Ovid Technologies
J2  - Syst
L1  - internal-pdf://0779698265/Babiano-Espinos-2019-Acceptability, feasibilit.pdf
LA  - English
N1  - Babiano-Espinosa, LuciaWolters, Lidewij HWeidle, BernhardOp de Beek, VivianPedersen, Sindre ACompton, ScottSkokauskas, Norbert
PY  - 2019
SP  - 284
T2  - Systematic Reviews
TI  - Acceptability, feasibility, and efficacy of Internet cognitive behavioral therapy (iCBT) for pediatric obsessive-compulsive disorder: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31747935
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31747935&amp;id=doi:10.1186%2Fs13643-019-1166-6&amp;issn=2046-4053&amp;isbn=&amp;volume=8&amp;issue=1&amp;spage=284&amp;pages=284&amp;date=2019&amp;title=Systematic+Reviews&amp;atitle=Acceptability%2C+feasibility%2C+and+efficacy+of+Internet+cognitive+behavioral+therapy+%28iCBT%29+for+pediatric+obsessive-compulsive+disorder%3A+a+systematic+review.&amp;aulast=Babiano-Espinosa&amp;pid=%3Cauthor%3EBabiano-Espinosa+L%3C%2Fauthor%3E%3CAN%3E31747935%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://systematicreviewsjournal.biomedcentral.com/track/pdf/10.1186/s13643-019-1166-6
VL  - 8
ER  -
TY  - JOUR
AB  - **CONTEXT:** 
Dietary interventions such as restrictive diets or supplements are common treatments for young people with autism spectrum disorder (ASD). Evidence for the efficacy of these interventions is still controversial.OBJECTIVE: To assess the efficacy of specific dietary interventions on symptoms, functions, and clinical domains in subjects with ASD by using a meta-analytic approach.

**DATA SOURCES:** 
Ovid Medline, PsycINFO, Embase databases.

**STUDY SELECTION:** 
We selected placebo-controlled, double-blind, randomized clinical trials assessing the efficacy of dietary interventions in ASD published from database inception through September 2017.

**DATA EXTRACTION:** 
Outcome variables were subsumed under 4 clinical domains and 17 symptoms and/or functions groups. Hedges&#039; adjusted g values were used as estimates of the effect size of each dietary intervention relative to placebo.

**RESULTS:** 
In this meta-analysis, we examined 27 double-blind, randomized clinical trials, including 1028 patients with ASD: 542 in the intervention arms and 486 in the placebo arms. Participant-weighted average age was 7.1 years. Participant-weighted average intervention duration was 10.6 weeks. Dietary supplementation (including omega-3, vitamin supplementation, and/or other supplementation), omega-3 supplementation, and vitamin supplementation were more efficacious than the placebo at improving several symptoms, functions, and clinical domains. Effect sizes were small (mean Hedges&#039; g for significant analyses was 0.31), with low statistical heterogeneity and low risk of publication bias.

**LIMITATIONS:** 
Methodologic heterogeneity among the studies in terms of the intervention, clinical measures and outcomes, and sample characteristics.

**CONCLUSIONS:**
This meta-analysis does not support nonspecific dietary interventions as treatment of ASD but suggests a potential role for some specific dietary interventions in the management of some symptoms, functions, and clinical domains in patients with ASD.
AD  - Fraguas, David. Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon and School of Medicine, Universidad Complutense de Madrid, Madrid, Spain; david.fraguas@iisgm.com.Fraguas, David. Centro de Investigacion Biomedica en Red Salud Mental, Madrid, Spain.Diaz-Caneja, Covadonga M. Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon and School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.Diaz-Caneja, Covadonga M. Centro de Investigacion Biomedica en Red Salud Mental, Madrid, Spain.Pina-Camacho, Laura. Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon and School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.Pina-Camacho, Laura. Centro de Investigacion Biomedica en Red Salud Mental, Madrid, Spain.Pina-Camacho, Laura. Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology, and Neuroscience, King&#039;s College London, London, United Kingdom.Moreno, Carmen. Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon and School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.Moreno, Carmen. Centro de Investigacion Biomedica en Red Salud Mental, Madrid, Spain.Duran-Cutilla, Manuel. Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon and School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.Ayora, Miriam. Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon and School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.Gonzalez-Vioque, Emiliano. Centro de Investigacion Biomedica en Red Salud Mental, Madrid, Spain.Gonzalez-Vioque, Emiliano. Unit of Diagnosis and Treatment of Congenital Metabolic Diseases, Hospital Clinico Universitario de Santiago de Compostela, Health Research Institute of Santiago de Compostela, Santiago, Spain; and.de Matteis, Mario. Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon and School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.Hendren, Robert L. Department of Psychiatry, University of California, San Francisco, San Francisco, California.Arango, Celso. Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon and School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.Arango, Celso. Centro de Investigacion Biomedica en Red Salud Mental, Madrid, Spain.Parellada, Mara. Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon and School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.Parellada, Mara. Centro de Investigacion Biomedica en Red Salud Mental, Madrid, Spain.
AN  - 31586029
AU  - Fraguas,
AU  - D.
AU  - Diaz-Caneja,
AU  - C.
AU  - M.
AU  - Pina-Camacho,
AU  - L.
AU  - Moreno,
AU  - C.
AU  - Duran-Cutilla,
AU  - M.
AU  - Ayora,
AU  - M.
AU  - Gonzalez-Vioque,
AU  - E.
AU  - de
AU  - Matteis,
AU  - M.
AU  - Hendren,
AU  - R.
AU  - L.
AU  - Arango,
AU  - C.
AU  - Parellada,
AU  - M.
DA  - Oct 04
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1542/peds.2018-3218
DP  - Ovid Technologies
J2  - Pediatrics
L1  - internal-pdf://3216139829/Fraguas-2019.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingOctFraguas, DavidDiaz-Caneja, Covadonga MPina-Camacho, LauraMoreno, CarmenDuran-Cutilla, ManuelAyora, MiriamGonzalez-Vioque, Emilianode Matteis, MarioHendren, Robert LArango, CelsoParellada, Marae20183218
PY  - 2019
SP  - 04
T2  - Pediatrics
TI  - Dietary Interventions for Autism Spectrum Disorder: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31586029
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31586029&amp;id=doi:10.1542%2Fpeds.2018-3218&amp;issn=0031-4005&amp;isbn=&amp;volume=&amp;issue=&amp;spage=e20183218&amp;pages=&amp;date=2019&amp;title=Pediatrics&amp;atitle=Dietary+Interventions+for+Autism+Spectrum+Disorder%3A+A+Meta-analysis.&amp;aulast=Fraguas&amp;pid=%3Cauthor%3EFraguas+D%3C%2Fauthor%3E%3CAN%3E31586029%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://pediatrics.aappublications.org/content/144/5/e20183218
UR  - https://pediatrics.aappublications.org/content/pediatrics/144/5/e20183218.full.pdf
VL  - 04
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Children living with parental cancer are vulnerable to distress and developmental disruption. This review aims to identify current interventions to support cancer patients&#039; children and summarise how effective these are based on children&#039;s reports. 

**METHODS: **
Between 25 May 2015 and 6 August 2018, a broad search strategy was used to identify relevant references. Seven databases were searched, and grey literature was also vetted. This review was informed by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and Cochrane guidelines. 

**RESULTS: **
Eight studies evaluating six interventions were retained. Research designs and interventions were heterogenous, and study quality was low. A limited number of significant results were reported by studies. These evidenced improvement for PTSD symptoms, emotional regulation, and depression. However, overall current interventions do not appear effective among patients&#039; children.

**CONCLUSION: **
Despite encouraging preliminary findings, interventions do not yet adequately support cancer patients&#039; children. There is a need for more tailored and targeted interventions. A theoretical model conceptualising the impact of parental cancer may assist this. 

**PRACTICE IMPLICATIONS: **
Findings will assist future intervention research by promoting standardised levels of care among cancer patients&#039; children, that is empirically supported, effective, and meets principles of non-maleficence.
AN  - 31109770
AU  - Alexander,
AU  - E.
AU  - O&#039;Connor,
AU  - M.
AU  - Rees,
AU  - C.
AU  - Halkett,
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.pec.2019.05.001
L1  - internal-pdf://3844836052/Alexander-2019-A systematic review of the curr.pdf
PY  - 2019
SP  - 02
T2  - Patient Education &amp; Counseling
TI  - A systematic review of the current interventions available to support children living with parental cancer
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31109770
UR  - https://www.sciencedirect.com/science/article/pii/S0738399118308905?via%3Dihub
VL  - 02
ER  -
TY  - JOUR
AB  - Social stories are a commonly used intervention practice in early childhood special education. Recent systematic reviews have documented the evidence base for social stories, but findings are mixed. We examined the efficacy of social stories for young children (i.e., 3-5 years) with challenging behavior across 12 single-case studies, which included 30 participants. The What Works Clearinghouse standards for single-case research design were used to evaluate the rigor of studies that included social stories as a primary intervention. For studies meeting standards, we synthesized findings on the efficacy of social stories using meta-analysis techniques and a parametric effect size measure, the log response ratio. Trends in participants&#039; response to treatment were also explored. Results indicate variability in rigor and efficacy for the use of social stories as an isolated intervention and in combination with other intervention approaches. Additional studies that investigate the efficacy of social stories as a primary intervention are warranted.
AD  - [Wahman, Charis L.] Ohio State Univ, Columbus, OH 43210 USA. [Pustejovsky, James E.] Univ Texas Austin, Austin, TX 78712 USA. [Ostrosky, Michaelene M.; Santos, Rosa Milagros] Univ Illinois, Urbana, IL 61801 USA.Wahman, CL (reprint author), Ohio State Univ, Coll Educ &amp; Human Ecol, Dept Educ Studies, 305 Annie &amp; John Glenn Ave, Columbus, OH 43210 USA.price.1375@osu.edu
AN  - WOS:000479739100001
AU  - Wahman,
AU  - C.
AU  - L.
AU  - Pustejovsky,
AU  - J.
AU  - E.
AU  - Ostrosky,
AU  - M.
AU  - M.
AU  - Santos,
AU  - R.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0271121419855692
J2  - Top. Early Child. Spec. Educ.
KW  - challenging behavior
KW  - social stories
KW  - young children
KW  - intervention
KW  - meta-analysis
KW  - log response ratio
KW  - robust variance-estimation
KW  - single-case designs
KW  - disruptive behavior
KW  - autism
KW  - intervention
KW  - students
KW  - story
KW  - model
KW  - disabilities
KW  - aggression
KW  - Education &amp; Educational Research
L1  - internal-pdf://1182812822/Wahman.pdf
LA  - English
M3  - Review; Early Access
N1  - ISI Document Delivery No.: IP0EYTimes Cited: 0Cited Reference Count: 68Wahman, Charis L. Pustejovsky, James E. Ostrosky, Michaelene M. Santos, Rosa MilagrosOffice of Special Education Programs (Project FOCAL) [H325D070061]; Institute of Educational Sciences, U.S. Department of Education [R305D160002]The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was supported in part by a leadership grant from the Office of Special Education Programs (Project FOCAL, H325D070061) and by Grant R305D160002 from the Institute of Educational Sciences, U.S. Department of Education. The opinions expressed are those of the author and do not represent the views of the Institute or the U.S. Department of Education.0Sage publications incThousand oaks1538-4845
PY  - 2019
SP  - 13
T2  - Topics in Early Childhood Special Education
TI  - Examining the Effects of Social Stories (TM) on Challenging Behavior and Prosocial Skills in Young Children: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000479739100001
ER  -
TY  - JOUR
AB  - The increase in autism spectrum disorder (ASD) population triggers a deep concern within public health. This alarming trend stresses the need for the development of effective strategies that might aid with this growing population. Exergaming has several advantages as an ASD intervention, such as flexible play, a private space for exercise, and diverse types of physical activity. The study aims to analyze the effectiveness of exergaming interventions on individuals with ASD. 

The systematic review was conducted in accordance with PRISMA guidelines. Studies which employed exergaming interventions on individuals with ASD were considered for inclusion. Exergaming-related changes in participants&#039; physical and cognitive functions were the main interest of the current review. Ten articles satisfied the predetermined eligibility criteria. Thematic coding categorized the main outcomes into two higher-order themes and five subthemes. The higher-order themes were physical performance and cognitive performance. 

The emerged subthemes were physical fitness, motor performance, intensity of physical activity, executive function, and self-perception. Following exergame interventions, individuals with ASD indicated significant improvements in physical fitness, executive function, and self-perception. Exergaming also increased participation in moderate-to-vigorous physical activity. In contrast, exergaming indicated small impact on emotional regulation and did not provide adequate opportunities for motor skill development. It is worth noting that only one randomized controlled trial was included in the current review. 

Future research would require more rigorous study designs to provide reliable evidence on the effectiveness of exergaming interventions for individuals with ASD. Exergaming interventions lead to improved physical and cognitive functions in individuals with ASD. It is suggested that exergaming be used as a feasible supplement to traditional physical activity programs for individuals with ASD.
AD  - [Fang, Qun; Pan, Zhujun] Mississippi State Univ, Dept Kinesiol, Mail Stop 6186,241 McCarthy Gymnasium, Mississippi State, MS 39762 USA. [Aiken, Christopher A.] New Mexico State Univ, Dept Kinesiol &amp; Dance, Las Cruces, NM 88003 USA. [Fang, Chao] Fourth Mil Med Univ, Sch Pharm, Inst Neurosci, Dept Pharmacol, Xian, Shaanxi, Peoples R China. [Fang, Chao] Harvard Med Sch, FM Kirby Neurobiol Ctr, Boston, MA USA.Pan, ZJ (reprint author), Mississippi State Univ, Dept Kinesiol, Mail Stop 6186,241 McCarthy Gymnasium, Mississippi State, MS 39762 USA.zp147@msstate.edu
AN  - WOS:000447595300001
AU  - Fang,
AU  - Q.
AU  - Aiken,
AU  - C.
AU  - A.
AU  - Fang,
AU  - C.
AU  - Pan,
AU  - Z.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1089/g4h.2018.0032
J2  - Games Health J.
KW  - Exergames
KW  - Autism
KW  - Physical performance
KW  - Cognitive function
KW  - disabilities monitoring network
KW  - randomized controlled-trials
KW  - daily
KW  - living skills
KW  - developmental-disabilities
KW  - executive function
KW  - clinical-trials
KW  - movement skills
KW  - motor-skills
KW  - pedro scale
KW  - children
KW  - Health Care Sciences &amp; Services
KW  - Public, Environmental &amp; Occupational
KW  - Health
KW  - Rehabilitation
L1  - internal-pdf://2618008007/Fang-Effects of Exergaming on Physical and Cog.pdf
LA  - English
M3  - Review; Early Access
N1  - ISI Document Delivery No.: GX3BGTimes Cited: 0Cited Reference Count: 64Fang, Qun Aiken, Christopher A. Fang, Chao Pan, Zhujun0Mary ann liebert, incNew rochelle2161-7856
PY  - 2019
SP  - 11
T2  - Games for Health Journal
TI  - Effects of Exergaming on Physical and Cognitive Functions in Individuals with Autism Spectrum Disorder: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000447595300001
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Increasingly, children are at risk of developing eating disorders. A systematic review and a meta-analysis were conducted to examine the effectiveness of universal eating disorder prevention interventions in improving body image, internalization of appearance ideals, and self-esteem among children aged 5-17 years old.

**METHODS:** 
Nine electronic databases were systematically searched from each database&#039;s point of inception to March 2019. The Cochrane Risk of Bias tool assessed each study&#039;s risk of bias, while the GRADE approach judged the overall evidence for each review outcome. A meta-analysis was conducted using the random-effect model to obtain standardized mean differences with 95% confidence intervals under the inverse variance method. Heterogeneity was assessed using I&lt;sup&gt;2&lt;/sup&gt; statistic and Cochran&#039;s Q chi-squared test. Publication bias was assessed using funnel plots.

**RESULTS:** 
A total of 24 studies (22 trials) were included in this review. Universal interventions were found to be effective in improving children&#039;s body esteem, self-esteem, and internalization of appearance ideals at postintervention and at follow-up timepoints. Subgroup analyses found that girls benefited more from these interventions than boys. Multisessional interventions with an optimal duration of approximately one month were found to be more effective.

**CONCLUSIONS:** 
The findings encourage the incorporation of universal preventive interventions into school curricula to benefit most children. Laypeople such as teachers can deliver these interventions, but content experts should address topics on body dissatisfaction. Due to the low quality of evidence, as accorded by the GRADE approach, current findings should be validated by future research.
AD  - Chua, Joelle Yan Xin. Nursing Division, KK Women&#039;s and Children&#039;s Hospital, Singapore, Singapore.Tam, Wilson. Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.Shorey, Shefaly. Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
AN  - 31746023
AU  - Chua,
AU  - J.
AU  - Y.
AU  - X.
AU  - Tam,
AU  - W.
AU  - Shorey,
AU  - S.
DA  - Nov 19
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.13164
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
L1  - internal-pdf://2953594453/Chua_et_al-2019-Journal_of_Child_Psychology_an.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingNovChua, Joelle Yan XinTam, WilsonShorey, Shefaly
PY  - 2019
SP  - 19
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Research Review: Effectiveness of universal eating disorder prevention interventions in improving body image among children: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31746023
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31746023&amp;id=doi:10.1111%2Fjcpp.13164&amp;issn=0021-9630&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2019&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Research+Review%3A+Effectiveness+of+universal+eating+disorder+prevention+interventions+in+improving+body+image+among+children%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Chua&amp;pid=%3Cauthor%3EChua+JYX%3C%2Fauthor%3E%3CAN%3E31746023%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/jcpp.13164
VL  - 19
ER  -
TY  - JOUR
AB  - **AIM: **
Youth at clinical high risk (CHR) for psychosis often exhibit difficulties in social functioning and poorer social functioning may be predictive of transition to a psychotic disorder. Therefore, the primary objective of this systematic review was to summarize the impact of all interventions on social functioning in CHR samples.

**METHOD: **
Electronic databases PsycINFO, CINAHL, Embase, EBM, and MEDLINE were searched from 1951 to June 2017. Studies were selected if they included any intervention that reported changes in social functioning in youth at CHR. Data were evaluated using random effects pairwise meta-analyses, stratified by time, and reported as the standardized mean difference (SMD). 

**RESULTS: **
Nineteen studies met our inclusion criteria, including a total of 1513 CHR participants. The mean age was 20.5 years and 47% were male. Cognitive behavioural therapy (4 studies) did not significantly improve social functioning at 6 months (SMD = 0.06; 95% confidence interval [CI] = -0.35, 0.46), 12 months (SMD = -0.15; 95% CI = -0.38, 0.08) and 18 months (SMD = 0.20; 95% CI = -0.10, 0.50). Omega-3 (2 studies) did not significantly improve social functioning at 6 months (SMD = 0.01; 95% CI = -0.21, 0.24) and 12 months (SMD = -0.08; 95% CI = -0.33, 0.17). Lastly, cognitive remediation (3 studies) did not significantly improve social functioning at 2- to 3-month follow-up (SMD = 0.13, 95% CI = -0.18, 0.43). 

**CONCLUSIONS: **
This systematic review and meta-analysis demonstrated that no treatment significantly improved social functioning in youth at CHR. Future randomized control trials are required that are designed to target and improve social functioning in youth at CHR for psychosis.
AN  - 29938910
AU  - Devoe,
AU  - D.
AU  - J.
AU  - Farris,
AU  - M.
AU  - S.
AU  - Townes,
AU  - P.
AU  - Addington,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/eip.12689
L1  - internal-pdf://2398863892/Devoe-2019-Interventions and social functionin.pdf
PY  - 2019
SP  - 169-180
T2  - Early Intervention in Psychiatry
TI  - Interventions and social functioning in youth at risk of psychosis: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29938910
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/eip.12689
VL  - 13
ER  -
TY  - JOUR
AB  - Individuals with autism spectrum disorder (ASD) may engage in repetitive social-communication behaviors that can limit their skill acquisition, access to reinforcement, and access to less restrictive settings. Basic and applied research indicates that variability, or the extent to which responses are topographically different from one another, is influenced by antecedent and consequence interventions. Our purpose in this study is to systematically review the literature on interventions to increase variable social-communication behaviors in individuals with ASD. We identified 32 studies through a database search and screened them using the What Works Clearinghouse (WWC) Single-Case Design Standards. Eighteen studies containing 55 cases met WWC Design Standards. We coded the descriptive characteristics and strength of evidence based on visual analysis from each of these 18 studies and calculated effect sizes using Tau-U. Our results indicate that most cases (65%) provide strong evidence of a functional relation between the interventions and varied social-communication behaviors, and the median Tau-U was .82. We discuss the implications of our results for practice and for future research on interventions designed to increase variability with this population.
AD  - [Wolfe, Katie] Univ South Carolina, Dept Educ Studies, Special Educ, Columbia, SC 29208 USA. [Pound, Sara; McCammon, Meka N.] Univ South Carolina, Columbia, SC 29208 USA. [Drasgow, Erik] Univ South Carolina, Special Educ, Columbia, SC 29208 USA. [Chezan, Laura C.] Old Dominion Univ, Special Educ, Norfolk, VA USA.Wolfe, K (reprint author), Univ South Carolina, Dept Educ Studies, 235B Wardlaw, Columbia, SC 29208 USA.kmwolfe@mailbox.sc.edu
AN  - WOS:000478513600001
AU  - Wolfe,
AU  - K.
AU  - Pound,
AU  - S.
AU  - McCammon,
AU  - M.
AU  - N.
AU  - Chezan,
AU  - L.
AU  - C.
AU  - Drasgow,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0145445519859803
J2  - Behav. Modificat.
KW  - autism
KW  - variability
KW  - social-communication
KW  - response classes
KW  - single-case research
KW  - response variability
KW  - lag schedule
KW  - mand
KW  - variability
KW  - children
KW  - reinforcement
KW  - resurgence
KW  - diversity
KW  - delay
KW  - Psychology
L1  - internal-pdf://2864663815/Wolfe.pdf
LA  - English
M3  - Review; Early Access
N1  - ISI Document Delivery No.: IN2MWTimes Cited: 0Cited Reference Count: 56Wolfe, Katie Pound, Sara McCammon, Meka N. Chezan, Laura C. Drasgow, Erik0Sage publications incThousand oaks1552-4167
PY  - 2019
SP  - 29
T2  - Behavior Modification
TI  - A Systematic Review of Interventions to Promote Varied Social-Communication Behavior in Individuals With Autism Spectrum Disorder
UR  - &lt;Go to ISI&gt;://WOS:000478513600001
ER  -
TY  - JOUR
AB  - **Aim** 
To evaluate the effectiveness of pharmacological interventions for managing non-respiratory sleep disturbances in children with neurodisabilities. 

**Method** 
We performed a systematic review and meta-analyses of randomized controlled trials (RCTs). We searched 16 databases, grey literature, and reference lists of included papers up to February 2017. Data were extracted and assessed for quality by two researchers (B.B., C.M., G.S., A.S., A.P.). 

**Results** 
Thirteen trials were included, all evaluating oral melatonin. All except one were at high or unclear risk of bias. There was a statistically significant increase in diary-reported total sleep time for melatonin compared with placebo (pooled mean difference 29.6min, 95% confidence interval [CI] 6.9-52.4, p=0.01). Statistical heterogeneity was high (97%). For the single RCT with low risk of bias, the unadjusted mean difference in total sleep time was 13.2 minutes (95% CI -13.3 to 39.7) favouring melatonin, while the mean difference adjusted for baseline total sleep time was statistically significant (22.4min, 95% CI 0.5-44.3, p=0.04). Adverse event profile suggested that melatonin was well-tolerated. 

**Interpretation** 
There is a paucity of evidence on managing sleep disturbances in children with neurodisabilities, and it is mostly of limited scope and poor quality. There is evidence of the benefit and safety of melatonin compared with placebo, although the extent of this benefit is unclear. What this paper adds Melatonin for the management of non-respiratory sleep disturbances in children with neurodisabilities was well tolerated with minimal adverse effects. The extent of benefit and which children might benefit most from melatonin use is uncertain. Benefit may be greatest in those with autism spectrum disorder; however, this finding should be interpreted with caution.
AN  - WOS:000473981600015
AU  - Parker,
AU  - A.
AU  - Beresford,
AU  - B.
AU  - Dawson,
AU  - V.
AU  - Elphick,
AU  - H.
AU  - Fairhurst,
AU  - C.
AU  - Hewitt,
AU  - C.
AU  - Scantlebury,
AU  - A.
AU  - Spiers,
AU  - G.
AU  - Thomas,
AU  - M.
AU  - Wright,
AU  - K.
AU  - McDaid,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/dmcn.14157
L1  - internal-pdf://2799936580/Parker-2019-Oral melatonin for non-respiratory.pdf
PY  - 2019
SP  - 880-+
T2  - Developmental Medicine and Child Neurology
TI  - Oral melatonin for non-respiratory sleep disturbance in children with neurodisabilities: systematic review and meta-analyses
UR  - &lt;Go to ISI&gt;://WOS:000473981600015
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617775/pdf/DMCN-61-880.pdf
VL  - 61
ER  -
TY  - JOUR
AB  - BAKGRUNN
Artikkelen er en kunnskapsoppsummering om effektene av det norske DUÅs skole- og barnehageprogram som bygger på Webster-Strattons indikerte program IY-TCM (Incredible Years Teacher Classroom Management Training). Den universelle versjonen tilbys personell (maks 25 personer pr. gruppe) som jobber med barn i 3-8 års alder i skoler, fritidsordning og barnehager, hovedsakelig i kommuner som har implementert DUÅs foreldretreningsprogram.

Skole- og barnehageprogrammets mål er en felles faglig plattform for målrettet arbeid med barns psykisk helse og forebygging av atferdsproblemer. Programopplæringen ledes av to gruppeledere over ca. ett skole-/barnehageår, og innbefatter seks opplæringsdager med påfølgende veiledning. Den strukturerte opplæringen fokuserer på emner som: 1) positiv relasjonsbygging, 2) ros, oppmuntring, oppmerksomhet, veiledning 3) belønningssystemer, 4) reduksjon av negativ atferd, 5) naturlige/arrangerte konsekvenser, og 6) emosjonell regulering og problemløsning. Oppfølgingsveiledning gis. Programeier er Regionalt kunnskapssenter for barn og unge Nord (RKBU Nord), UiT Norges arktiske universitet (Tromsø).

METODE
Kunnskapsoppsummeringen bygger på et systematisk litteratursøk i de nasjonale og internasjonale databasene Embase, Medline, Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS, SweMed, Bibsys og Google Scholar. Det ble også innhentet informasjon om tiltaket fra tiltakseier.

RESULTATER
Resultatene inkluderer en vurdering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Programmet har et solid teoretisk fundament og det gis en god beskrivelse av programmets innholdskomponenter og opplæringsstrategier. To norske kvasi-eksperimentelle studier basert på lærervurderinger, publisert i fire artikler, ble inkludert i kunnskapsoppsummeringen. Resultatene indikerer at programmet kan redusere problematferd og øke sosial kompetanse hos barn i 3-8 års alderen, samt bidra til positive endringer i elev-lærer relasjoner og foreldres involvering i barnas skolegang. Med utgangspunkt i totalutvalget synes kortidseffektene imidlertid å være små til marginale. Resultatene tyder på at programmet har en større effekt på redusering av eksternaliseringsproblemer og elev-lærer konflikter for høyrisikobarn. Innenfor denne gruppen ble det i tillegg funnet en moderat effekt på skolefaglige prestasjoner. Det knytter seg noe usikkerhet til evalueringsresultatenes pålitelighet (særlig indre validitet). Per dags dato bør ikke programmet omtales som skoleomfattende, da det kun implementeres på 1. &ndash; 3. klassetrinn. Det er behov for en implementeringsmanual for skoler og barnehager og bedre kvalitetskontroll.

KONKLUSJON
DUÅs skole- og barnehageprogram klassifiseres på evidensnivå 4 &ndash; Tiltak med tilfredsstillende dokumentasjon på effekt.
AU  - Sørlie,
AU  - M-A.,
AU  - Breivik,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2019
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: De Utrolige Årenes (DUÅs) skole- og barnehageprogram (1. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/de-utrolige-arenes-duas-skole-og-barnehageprogram-1-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Research trials of early intervention (EI) programs for children with autism spectrum disorder (ASD) generally demonstrate medium-to-large gains, on average, compared with &quot;treatment as usual,&quot; in different developmental domains. Almost all children with ASD receive their treatment through community-based services, however, and studies suggest that evidence-based interventions rarely make their way into community practice. Understanding the effectiveness of community-based EI and factors associated with these effects is the first step in developing strategies for wide-scale implementation of effective EI. 

**METHODS:** 
Studies of community-based EI for children with ASD were identified through a systematic search. Changes in cognitive, communication, social, and adaptive functioning from pre-treatment to post-treatment were assessed using standardized mean gain scores. Effect sizes were estimated using random effects models. Moderators of interest included type of community EI program, year of publication, intervention duration, and sample selection. Moderator effects were assessed using analysis of variance of mixed-effects models and meta-regression analyses. 

**RESULTS:** 
Forty-six groups from 33 studies met inclusion criteria (1,713 participants, mean age 37.4 months, 81.1% male). There were small but statistically significant gains in each of the four domains. Hedges&#039;s g ranged from 0.21 for adaptive behavior to 0.32 for communication outcomes, after removing outliers and correcting for publication bias. EI programs associated with universities and hospitals were superior, on average, to other community EI programs for cognitive and adaptive behavior outcomes. Intervention duration was negatively associated with effect sizes for communication and adaptive behavior outcomes. 

**CONCLUSIONS:** 
These results indicate that there remains a large gap between outcomes observed in community settings and those reported in efficacy trials.
AN  - 31206690
AU  - Nahmias,
AU  - A.
AU  - S.
AU  - Pellecchia,
AU  - M.
AU  - Stahmer,
AU  - A.
AU  - C.
AU  - Mandell,
AU  - D.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.13073
L1  - internal-pdf://1765057401/Nahmias-2019-Effectiveness of community-based.pdf
PY  - 2019
SP  - 17
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Effectiveness of community-based early intervention for children with autism spectrum disorder: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31206690
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcpp.13073
VL  - 17
ER  -
TY  - JOUR
AB  - As the demand for childhood mental health intervention rises, there is a need for increased evidentiary support for developmentally sensitive approaches that address childhood mental health symptoms. 

Child-centered play therapy (CCPT) has been recognized as one of the most frequently used approaches for this population due to its responsiveness to cognitive and psychosocial developmental levels. A meta-analysis was conducted to evaluate the degree of effectiveness of CCPT for decreasing common childhood mental health symptoms based on single-case research design (SCRD) data. 

The systematic search strategy yielded 11 CCPT SCRD studies with 65 total effect sizes that were analyzed to determine omnibus treatment effect. Results indicated CCPT had a moderate effect for decreasing internalizing symptoms, externalizing symptoms, and social skill deficits. 

This study adds to the evidence base for CCPT incorporating SCRD data into the corpus of CCPT meta-analytic data and provides further support that CCPT should be considered an appropriate intervention to address common childhood mental health symptoms. 

Based on these results, the authors provide implications for CCPT practitioners and for future directions to build the intervention&#039;s evidence base. 

(PsycINFO Database Record (c) 2019 APA, all rights reserved)
AN  - 2019-07147-001
AU  - Pester,
AU  - Danielle
AU  - Lenz,
AU  - A.
AU  - Dell&#039;Aquila,
AU  - Julia
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/pla0000098
L1  - internal-pdf://1025755761/Pester-2019-Meta-analysis of single-case evalu.pdf
PY  - 2019
SP  - No Pagination Specified
T2  - International Journal of Play Therapy
TI  - Meta-analysis of single-case evaluations of child-centered play therapy for treating mental health symptoms
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2019-07147-001
ER  -
TY  - JOUR
AB  - **Background**
Clinical guidelines recommend outpatient care for the majority of people with an eating disorder. The optimal use of inpatient treatmentor combination of inpatient and partial hospital care is disputed and practice varies widely.

**Objectives**
To assess the effects of treatment setting (inpatient, partial hospitalisation, or outpatient) on the reduction of symptoms and increase in remission rates in people with:1. Anorexia nervosa and atypical anorexia nervosa;2. Bulimia nervosa and other eating disorders.

**Search methods**
We searched Ovid MEDLINE (1950- ), Embase (1974- ), PsycINFO (1967- )and the Cochrane Central Register of ControlledTrials (CENTRAL) to 2 July 2018. An earlier search of these databases was conducted via the Cochrane Common Mental DisordersControlled Trial Register (CCMD-CTR) (all years to 20 November 2015). We also searched the WHO International Clinical TrialsRegistry Platform and ClinicalTrials.gov (6 July 2018). We rana forward citation search on the Web of Science to identify additional reports citing any of the included studies, and screened reference lists of included studies and relevant reviews identified during our searches.

**Selection criteria**
We included randomised controlled trials that tested the efficacy of inpatient, outpatient, or partial hospital settings for treatment ofeating disorder in adults, adolescents, and children, whose diagnoses were determined according to the DSM-5, or other internationally accepted diagnostic criteria. We excluded trials of treatment setting for medical or psychiatric complications or comorbidities (e.g.hypokalaemia, depression) of an eating disorder.

**Data collection and analysis**
We followed standard Cochrane procedures to select studies, extract and analyse data, and interpret and present results. We extracted data according to the DSM-5 criteria. We used the Cochrane tool to assess risk of bias. We used the mean (MD) or standardised mean difference (SMD) for continuous data outcomes, and the riskratio (RR) for binary outcomes. We included the 95% confidenceinterval (CI) with each result. We presented the quality of the evidence and estimate of effect for weight or body mass index (BMI)and acceptability (number who completed treatment), in a &rsquo;Summary of findings&rsquo; table for the comparison for which we had sufficient data to conduct a meta-analysis.

**Main results**
We included five trials in our review. Four trials included a total of 511 participants with anorexia nervosa, and one trial had 55 participants with bulimia nervosa. Three trials are awaiting classification, and may be included in future versions of this review. We assessed a risk of bias from lack of blinding of participants and therapists in all trials, and unclear risk for allocation concealment and randomisation in one study.We had planned four comparisons, and had data for meta-analyses for one. For anorexia nervosa, there may be little or no difference between specialist inpatient care and active outpatient or combined brief hospital and outpatient care in weight gain at 12 months after the start of treatment (standardised mean difference (SMD) -0.22, 95% CI -0.49 to 0.05; 2 trials, 232 participants; low-quality evidence). People may be more likely to complete treatment when randomised to outpatient care settings, but this finding is very uncertain (risk ratio (RR) 0.75, 95% CI 0.64 to 0.88; 3 trials, 319 participants; very low-quality evidence). We downgraded the quality of the evidence for these outcomes because of risks of bias, small numbers of participants and events, and variable level of specialistexpertise and intensity of treatment.We had no data, or data from only one trial for the primary outcomes for each of the other three comparisons.No trials measured weight or acceptance of treatment for anorexia nervosa, when comparing inpatient care provided by a specialist eating disorder service and health professionals and a waiting list, no active treatment, or treatment as usual.There was no clear difference in weight gain between settings,and only slightly more acceptance for the partial hospital setting overspecialist inpatient care for weight restoration in anorexia nervosa. There was no clear difference in weight gain or acceptability of treatment between specialist inpatient care and partial hospital care for bulimia nervosa, and other binge eating disorders.

**Authors&rsquo; conclusions**
There was insufficient evidence to conclude whether any treatment setting was superior for treating people with moderately severe (or less) anorexia nervosa, or other eating disorders.More research is needed for all comparisons of inpatient care versus alternate care.
AU  - Hay,
AU  - P.
AU  - J.
AU  - Touyz,
AU  - S.
AU  - Claudino,
AU  - A.
AU  - M.
AU  - Lujic,
AU  - S.
AU  - Smith,
AU  - C.
AU  - A.
AU  - Madden,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD010827.pub2
L1  - internal-pdf://3926486242/Hay-2019-Inpatient versus outpatient care, par.pdf
PY  - 2019
T2  - Cochrane Database of Systematic Reviews
TI  - Inpatient versus outpatient care, partial hospitalisation and waiting list for people with eating disorders
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
This systematic review and meta-analysis examined the effectiveness of the Buzzy device combining cold and vibration for needle-related procedural pain in children. 

**MATERIALS AND METHODS: **
Databases search was conducted from inception to December 2017 to identify randomized controlled trials using the Buzzy device for pain management in children undergoing needle-related procedures. Selection of studies, data extraction, and assessment of risk of bias and quality of evidence were independently performed by 2 reviewers. Quantitative and qualitative analyses were conducted. 

**RESULTS: **
A total of 9 studies involving 1138 participants aged between 3 and 18 years old were included in the systematic review and 7 were suitable for meta-analysis. The meta-analysis compared the Buzzy device with a no-treatment comparator and the effect of the device was significant in reducing self-report procedural pain (standardized mean difference [SMD]: -1.11; 95% confidence interval [CI]: -1.52 to -0.70; P&lt;0.0001), parent-reported procedural pain (SMD: -0.94; 95% CI: -1.62 to -0.27; P=0.006), observer-report procedural pain (SMD: -1.19; 95% CI: -1.90 to -0.47; P=0.001), observer-reported procedural anxiety (SMD -1.37; 95% CI: -1.77 to -0.96; P&lt;0.00001), and parent-reported procedural anxiety (SMD -1.36; 95% CI: -2.11 to -0.61; P=0.0004). There was no significant difference for the success of the procedure at first attempt and the occurrence of adverse events. 

**DISCUSSION: **
The Buzzy device seems to be a promising intervention for procedural pain management in children. However, the comparative effect is uncertain due to the presence of significant heterogeneity and very low-quality evidence. There is a need to improve the methodological quality and rigor in the design of future trials to conclude to the efficacy of the Buzzy device.
AN  - 30829735
AU  - Ballard,
AU  - A.
AU  - Khadra,
AU  - C.
AU  - Adler,
AU  - S.
AU  - Trottier,
AU  - E.
AU  - D.
AU  - Le
AU  - May,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/AJP.0000000000000690
L1  - internal-pdf://0618827327/Ballard-2019-Efficacy of the Buzzy Device for.pdf
PY  - 2019
SP  - 532-543
T2  - Clinical Journal of Pain
TI  - Efficacy of the Buzzy Device for Pain Management During Needle-related Procedures: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30829735
VL  - 35
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Youth often experience unique pathways into homelessness, such as family conflict, child abuse and neglect. Most research has focused on adult homeless populations, yet youth have specific needs that require adapted interventions. This review aims to synthesize evidence on interventions for youth and assess their impacts on health, social, and equity outcomes.

**METHODS:** 
We systematically searched Medline, Embase, PsycINFO, and other databases from inception until February 9, 2018 for systematic reviews and randomized controlled trials on youth interventions conducted in high income countries. We screened title and abstract and full text for inclusion, and data extraction were completed in duplicate, following the PRISMA-E (equity) review approach.

**RESULTS:** 
Our search identified 11,936 records. Four systematic reviews and 18 articles on randomized controlled trials met the inclusion criteria. Many studies reported on interventions including individual and family therapies, skill-building, case management, and structural interventions. Cognitive behavioural therapy led to improvements in depression and substance use, and studies of three family-based therapies reported decreases in substance use. Housing first, a structural intervention, led to improvements in housing stability. Many interventions showed inconsistent results compared to services as usual or other interventions, but often led to improvements over time in both the intervention and comparison group. The equity analysis showed that equity variables were inconsistently measured, but there was data to suggest differential outcomes based upon gender and ethnicity.

**CONCLUSIONS:** 
This review identified a variety of interventions for youth experiencing homelessness. Promising interventions include cognitive behavioural therapy for addressing depression, family-based therapy for substance use outcomes, and housing programs for housing stability. Youth pathways are often unique and thus prevention and treatment may benefit from a tailored and flexible approach.
AD  - Wang, Jean Zhuo. University of Ottawa Faculty of Medicine, Bruyere Research Institute, University of Ottawa, Ottawa, ON, Canada.Mott, Sebastian. McGill University Faculty of Medicine, Montreal, QC, Canada.Magwood, Olivia. C.T. Lamont Primary Health Care Research Centre, Bruyere Research Institute, Ottawa, ON, Canada.Mathew, Christine. Bruyere Research Institute, Ottawa, ON, Canada.Mclellan, Andrew. University of Toronto, Faculty of Nursing, Toronto, ON, Canada.Mclellan, Andrew. Department of Family Medicine, University of Ottawa, Ottawa, ON, Canada.Kpade, Victoire. McGill University Faculty of Medicine, Montreal, QC, Canada.Gaba, Priya. Department of Family Medicine, University of Ottawa, Ottawa, ON, Canada.Kozloff, Nicole. Centre for Addiction and Mental Health, Department of Psychiatry and Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.Pottie, Kevin. Departments of Family Medicine and Epidemiology and Community Medicine, Bruyere Research Institute, University of Ottawa, Ottawa, ON, Canada. kpottie@uottawa.ca.Andermann, Anne. Department of Family Medicine and Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Montreal, QC, Canada.
AN  - 31727031
AU  - Wang,
AU  - J.
AU  - Z.
AU  - Mott,
AU  - S.
AU  - Magwood,
AU  - O.
AU  - Mathew,
AU  - C.
AU  - McLellan,
AU  - A.
AU  - Kpade,
AU  - V.
AU  - Gaba,
AU  - P.
AU  - Kozloff,
AU  - N.
AU  - Pottie,
AU  - K.
AU  - Andermann,
AU  - A.
DA  - Nov 14
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s12889-019-7856-0
DP  - Ovid Technologies
J2  - BMC Public Health
L1  - internal-pdf://1867929967/Wang-2019-The impact of interventions for yout.pdf
LA  - English
N1  - Wang, Jean ZhuoMott, SebastianMagwood, OliviaMathew, ChristineMclellan, AndrewKpade, VictoireGaba, PriyaKozloff, NicolePottie, KevinAndermann, Anne
PY  - 2019
SP  - 1528
T2  - BMC Public Health
TI  - The impact of interventions for youth experiencing homelessness on housing, mental health, substance use, and family cohesion: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31727031
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31727031&amp;id=doi:10.1186%2Fs12889-019-7856-0&amp;issn=1471-2458&amp;isbn=&amp;volume=19&amp;issue=1&amp;spage=1528&amp;pages=1528&amp;date=2019&amp;title=BMC+Public+Health&amp;atitle=The+impact+of+interventions+for+youth+experiencing+homelessness+on+housing%2C+mental+health%2C+substance+use%2C+and+family+cohesion%3A+a+systematic+review.&amp;aulast=Wang&amp;pid=%3Cauthor%3EWang+JZ%3C%2Fauthor%3E%3CAN%3E31727031%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857126/pdf/12889_2019_Article_7856.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - **Background:** 
There is growing evidence that physical activity (PA) is beneficial for the mental health of young people. One area that has been widely examined is the impact of PA on &#039;the self&#039;, which is a term that encompasses a range of specific and related terms (e.g. self-esteem, self-efficacy, self-perceptions). There is evidence that PA is strongly associated with &#039;the self&#039; in childhood and beyond. However, the impact of the specific PA of resistance training (RT) is not yet clear. The purpose of this review was to advance knowledge on the potential of RT for enhancing mental health by examining the effect of RT interventions on &#039;the self&#039; in youth. 

**Method(s):** 
This systematic review followed the PRISMA guidelines (PROSPERO registration number CRD42016038365). Electronic literature databases were searched from the year of their inception to October 2018. The search included English language articles that examined the effect of isolated RT on the broad term of &#039;the self&#039; in youth, with participants of school age (5-18 years). Data were extracted using an electronic form by one reviewer with 10% conducted by a second reviewer. The &#039;Quality Assessment Tool for Quantitative Studies&#039; was used to assess the quality and risk of bias and was conducted by two reviewers. 

**Result(s):** 
From seven peer-reviewed studies, ten data sets were included exploring seven outcomes related to &#039;the self&#039; in participants aged between 10 and 16 years. Four of these studies (including seven data sets) were combined in a meta-analysis, with results from the remaining three studies reported separately. Significant intervention effects were identified for resistance training self-efficacy (Hedges&#039; g = 0.538, 95% CI 0.254 to 0.822, P &lt; 0.001), physical strength (Hedges&#039; g = 0.289, 95% CI 0.067 to 0.511, P = 0.011), physical self-worth (Hedges&#039; g = 0.319, 95% CI 0.114 to 0.523, P = 0.002) and global self-worth (Hedges&#039; g = 0.409, 95% 0.149 to 0.669, P = 0.002). Although not statistically significant, the effect sizes for the remaining three outcomes were body attractiveness (Hedges&#039; g = 0.211, 95% CI - 0.031 to 0.454, P = 0.087), physical condition (Hedges&#039; g = 0.089, 95% CI - 0.238 to 0.417, P = 0.593) and sport competence (Hedges&#039; g = 0.004, 95% CI - 0.218 to 0.225, P = 0.974). There was variable quality of studies, with just two studies being classified as &#039;strong&#039;. 

**Conclusion(s):** 
This is the first review to synthesise research on the effects of isolated RT interventions on &#039;the self&#039;. The findings indicate that RT has a positive impact on some aspects of &#039;the self&#039; in youth. More high-quality studies should be conducted to further investigate this topic. If validated, this type of intervention could have a positive impact on &#039;the self&#039; and ultimately improve the health of individuals not only during childhood but as they progress through life. Copyright &copy; 2019, The Author(s).
AN  - 2002259927
AU  - Collins,
AU  - H.
AU  - Booth,
AU  - J.
AU  - N.
AU  - Duncan,
AU  - A.
AU  - Fawkner,
AU  - S.
AU  - Niven,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s40798-019-0205-0
L1  - internal-pdf://2659116205/Collins-2019-The Effect of Resistance Training.pdf
PY  - 2019
TI  - The Effect of Resistance Training Interventions on &#039;The Self&#039; in Youth: a Systematic Review and Meta-analysis
UR  - https://sportsmedicine-open.springeropen.com/articles
UR  - https://sportsmedicine-open.springeropen.com/track/pdf/10.1186/s40798-019-0205-0
VL  - 5 (1) (no pagination)
ER  -
TY  - JOUR
AB  - Mentoring programs, which pair youth with caring, non-parental adults with the goal of promoting positive youth development, are an increasingly popular strategy for early intervention with at-risk youth. 

However, important questions remain about the extent to which these interventions improve youth outcomes. The present study involved a comprehensive meta-analysis of all outcome studies of intergenerational, one-on-one youth mentoring programs written in the English language between 1975 and 2017, using rigorous inclusion criteria designed to align with developmental theories of youth mentoring. 

Analysis of 70 mentoring outcome studies, with a sample size of 25,286 youth (average age of 12 years old), yielded a statistically significant effect of mentoring programs across all youth outcomes. The observed effect size fell within the medium/moderate range according to empirical guidelines derived from universal prevention programs for youth, and was consistent with past meta-analyses of youth mentoring. 

Moderation analyses indicated that programs serving a larger proportion of male youth, deploying a greater percentage of male mentors or mentors with a helping profession background, and requiring shorter meetings yielded larger effect sizes, as did evaluations that relied on questionnaires and youth self-report. 

Taken together, these findings provide some support for the efficacy of mentoring interventions, while also emphasizing the need to remain realistic about the modest impact of these programs as currently implemented, and highlighting opportunities for improving the quality and rigor of mentoring practices.
AN  - 30661211
AU  - Raposa,
AU  - E.
AU  - B.
AU  - Rhodes,
AU  - J.
AU  - Stams,
AU  - Gjjm
AU  - Card,
AU  - N.
AU  - Burton,
AU  - S.
AU  - Schwartz,
AU  - S.
AU  - Sykes,
AU  - L.
AU  - A.
AU  - Y.
AU  - Kanchewa,
AU  - S.
AU  - Kupersmidt,
AU  - J.
AU  - Hussain,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10964-019-00982-8
L1  - internal-pdf://1048571977/Raposa-2019-The Effects of Youth Mentoring Pro.pdf
PY  - 2019
SP  - 423-443
T2  - Journal of Youth &amp; Adolescence
TI  - The Effects of Youth Mentoring Programs: A Meta-analysis of Outcome Studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=30661211
UR  - https://link.springer.com/article/10.1007%2Fs10964-019-00982-8
VL  - 48
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
The study primarily focuses on systematically analyzing the effectiveness of using social stories as interventions for inappropriate social behavior in individuals with ASD. 

**OBJECTIVE(S):** 
This study also reviewed the effectiveness of integration of technology when using social stories. 

**METHOD(S):** 
Several databases were systematically searched using key words. Exclusion and inclusion criteria were applied to identify appropriate peer-reviewed journal articles for inclusion. Effect size, quality of study, and Gray&#039;s criteria were used to assess the efficacy of social stories as interventions for inappropriate behaviors in individuals with ASD. 

**RESULT(S):** 
The search yielded 23 peer-reviewed journal articles. The literature indicates that social stories are, in fact, effective in reducing inappropriate social behaviors among such children. A few studies had been about applied social stories with use of technology. However, some researchers have argued that social studies cannot be used alone. 

**CONCLUSION(S):** 
There is a need to ensure that teachers involve themselves fully in the process and include verbal prompts and computer-presented social stories employing multimedia features. According to findings of the literature, further research is needed on the effectiveness of social stories when incorporated with other verbal prompts and multimedia features. 
Copyright &copy; 2019 - IOS Press and the authors. All rights reserved.
AD  - (Aldabas) Department of Special Education, College of Education, King Saud University, Riyadh, Saudi ArabiaR. Aldabas, Department of Special Education, College of Education, King Saud University, Riyadh, Saudi Arabia. E-mail: raldabas@KSU.EDU.SA
AN  - 628615525
AU  - Aldabas,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3233/TAD-180218
DP  - Ovid Technologies
KW  - autism
KW  - Behavior intervention
KW  - social intervention
KW  - social skills
KW  - social stories
KW  - antisocial personality disorder/th [Therapy]
KW  - bibliographic database
KW  - child
KW  - child psychiatry
KW  - clinical effectiveness
KW  - education
KW  - educational technology
KW  - effect size
KW  - human
KW  - intervention study
KW  - medical literature
KW  - medical sociology
KW  - medical technology
KW  - Medline
KW  - methodology
KW  - peer review
KW  - PsycINFO
KW  - review
KW  - scientist
KW  - social behavior
KW  - social competence
KW  - social learning
KW  - social psychiatry
KW  - storytelling
KW  - systematic review
KW  - thematic analysis
KW  - multimedia
KW  - social story
L1  - internal-pdf://0158153509/Aldabas-2019.pdf
LA  - English
M3  - Review
PY  - 2019
SP  - 1-13
T2  - Technology and Disability
TI  - Effectiveness of social stories for children with autism: A comprehensive review
UR  - https://www.iospress.nl/journal/technology-and-disability/
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=628615525
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.3233%2FTAD-180218&amp;issn=1055-4181&amp;isbn=&amp;volume=31&amp;issue=1-2&amp;spage=1&amp;pages=1-13&amp;date=2019&amp;title=Technology+and+Disability&amp;atitle=Effectiveness+of+social+stories+for+children+with+autism%3A+A+comprehensive+review&amp;aulast=Aldabas&amp;pid=%3Cauthor%3EAldabas+R.%3C%2Fauthor%3E%3CAN%3E628615525%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://content.iospress.com/articles/technology-and-disability/tad180218
VL  - 31
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** 
To assess benefits and harms of cognitive behavioral therapy (CBT) versus no intervention or versus other interventions for pediatric obsessive-compulsive disorder (OCD).

**METHOD:** 
We searched for randomized clinical trials of CBT for pediatric OCD. Primary outcomes were OCD severity, serious adverse events, and level of functioning. Secondary outcomes were quality of life and adverse events. Remission from OCD was included as an exploratory outcome. We assessed risk of bias and evaluated the certainty of the evidence with the Grading of Recommendations Assessment, Development and Evaluation.

**RESULTS:** 
We included nine trials (N=645) comparing CBT with no intervention and three trials (N=146) comparing CBT with selective serotonin reuptake inhibitors (SSRIs). Compared with no intervention, CBT decreased OCD severity (mean difference [MD]=-8.51, 95% CI -10.84 to -6.18, p&lt;.00001, low certainty), improved level of functioning (patient-rated: standardized MD [SMD]=-0.90, 95% CI -1.19 to -0.62, p&lt;.00001, very low certainty; parent-rated: SMD=-0.68, 95% CI -1.12 to -0.23, p=.003, very low certainty) had similar proportions of participants with adverse events (risk ratio=1.06, 95% CI 0.93 to 1.22, p=0.39, GRADE: low certainty), and was associated with reduced risk of still having OCD (risk ratio=0.50, 95% CI 0.37 to 0.67, p&lt;.00001, very low certainty). We had insufficient data to assess the effect of CBT versus no intervention on serious adverse events and quality of life. Compared with SSRIs, CBT led to similar decreases in OCD severity (MD=-0.75, 95% CI -3.79 to 2.29, p=.63, GRADE: very low certainty) and was associated with similar risk of still having OCD (risk ratio=0.85, 95% CI 0.66 to 1.09, p=.20, very low certainty). We had insufficient data to assess the effect of CBT versus SSRIs on serious adverse events, level of functioning, quality of life, and adverse events.

**CONCLUSION:** 
CBT may be more effective than no intervention and comparable to SSRIs for pediatric OCD, but we are very uncertain about the effect estimates.
AD  - Uhre, Camilla Funch. Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region, Denmark; Faculty of Health Sciences, University of Copenhagen, Denmark. Electronic address: Camilla.funch.staugaard@regionh.dk.Uhre, Valdemar Funch. Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region, Denmark; Faculty of Health Sciences, University of Copenhagen, Denmark; Danish Research Centre for Magnetic Resonance, Hvidovre Hospital, Denmark.Lonfeldt, Nicole Nadine. Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region, Denmark.Pretzmann, Linea. Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region, Denmark.Vangkilde, Signe. Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region, Denmark; University of Copenhagen, Denmark.Plessen, Kerstin Jessica. Lausanne University Hospital, Faculty of Biology and Medicine, Lausanne, Switzerland.Gluud, Christian. Copenhagen Trial Unit, Centre for Clinical Intervention Research, Copenhagen University Hospital, Copenhagen, Denmark; Cochrane Hepato-Biliary Group, Copenhagen Trial Unit, Centre for Clinical Intervention Research, Copenhagen University Hospital, Copenhagen, Denmark.Jakobsen, Janus Christian. Copenhagen Trial Unit, Centre for Clinical Intervention Research, Copenhagen University Hospital, Copenhagen, Denmark; Holbaek Hospital, Denmark.Pagsberg, Anne Katrine. Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region, Denmark; Faculty of Health Sciences, University of Copenhagen, Denmark.
AN  - 31589909
AU  - Uhre,
AU  - C.
AU  - F.
AU  - Uhre,
AU  - V.
AU  - F.
AU  - Lonfeldt,
AU  - N.
AU  - N.
AU  - Pretzmann,
AU  - L.
AU  - Vangkilde,
AU  - S.
AU  - Plessen,
AU  - K.
AU  - J.
AU  - Gluud,
AU  - C.
AU  - Jakobsen,
AU  - J.
AU  - C.
AU  - Pagsberg,
AU  - A.
AU  - K.
DA  - Oct 04
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2019.08.480
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
L1  - internal-pdf://2967563531/Uhre-2019-Systematic Review and Meta-Analysis_.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingOctUhre, Camilla FunchUhre, Valdemar FunchLonfeldt, Nicole NadinePretzmann, LineaVangkilde, SignePlessen, Kerstin JessicaGluud, ChristianJakobsen, Janus ChristianPagsberg, Anne KatrineS0890-8567(19)32069-6
PY  - 2019
SP  - 04
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Systematic Review and Meta-Analysis: Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in Children and Adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=31589909
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31589909&amp;id=doi:10.1016%2Fj.jaac.2019.08.480&amp;issn=0890-8567&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2019&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Systematic+Review+and+Meta-Analysis%3A+Cognitive-Behavioral+Therapy+for+Obsessive-Compulsive+Disorder+in+Children+and+Adolescents.&amp;aulast=Uhre&amp;pid=%3Cauthor%3EUhre+CF%3C%2Fauthor%3E%3CAN%3E31589909%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
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VL  - 04
ER  -
TY  - JOUR
AB  - **Introduction:** 
While there is a very high rate of comorbidity of autism and ADHD, there are controversies about prescribing stimulants in children with autism. This is a systematic review about the effect of stimulants on irritability in children with both autism and ADHD. 

**Methods:** 
A systematic review was conducted to study the possible effect of stimulants on irritability in autism and ADHD using the databases of PubMed, Scopus, EMBASE, and ScienceDirect in September 2018. Eligible clinical trials of stimulants in the treatment of Autism and ADHD without restriction of language were included. The primary outcome was irritability score. The full texts of relevant articles were studied, and their references were scanned for any possible related article. 

**Results:** 
Out of 1,315 citations, there were 26 relevant articles. Of the relevant articles, 16 were not interventional studies and were excluded. There were 10 interventional studies. None of them considered irritability as a main outcome. Also, none of them studied the effect of stimulants on irritability in autism plus ADHD. Current uncontrolled evidence about the association of stimulants with irritability is controversial. 

**Conclusion:** 
The current evidence is not enough to support or discourage the effect of stimulants on irritability in children and adolescents with both autism and ADHD. Well-designed controlled clinical trials need to be conducted for this ignored research area.
AN  - WOS:000470673100002
AU  - Ghanizadeh,
AU  - A.
AU  - Molla,
AU  - M.
AU  - Olango,
AU  - G.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2147/ndt.S194022
L1  - internal-pdf://1117822896/Ghanizadeh-2019-The effect of stimulants on ir.pdf
PY  - 2019
SP  - 1547-1555
T2  - Neuropsychiatric Disease and Treatment
TI  - The effect of stimulants on irritability in autism comorbid with ADHD: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000470673100002
UR  - https://www.dovepress.com/getfile.php?fileID=50361
VL  - 15
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering av effektene på De Utrolige Årenes universalprogram Oppmerksomme og utviklingsstøttende foreldre (DUÅ Universal) i Norden. DUÅ Universal er et universalforebyggende program som gis til foreldre, for å forebygge atferdsvansker og styrke sosial og emosjonell kompetanse hos barn i alderen 2 til 6 år. Regionalt kunnskapssenter for barn og unge &ndash; Nord (RKBU Nord), er tiltaksleverandør i Norge og har det nasjonale ansvaret for å gi opplæring i programmet. DUÅ Universal er et av flere programmer i DUÅs programserie som er opprinnelig utviklet i USA (www.incredibleyears.com).

METODE
DUÅ Universal er vurdert og klassifisert i henhold til Ungsinn sine kriterier og prosedyrer for beskrivelse av tiltaket, samt en oppsummering av effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Det ble gjort litteratursøk i databasene Embase, Medline og Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS og SweMed. Søket resulterte i tre artikler basert på en norsk effektstudie som ble inkludert. I tillegg er det innhentet informasjon om DUÅ Universal gjennom dokumentasjon fra tiltaksleverandør (deriblant manual, veiledere og annet materiell). Denne kunnskapsoppsummeringen er begrenset til det universalforebyggende tiltaket.

RESULTATER
DUÅ Universal er godt beskrevet i flere dokumenter blant annet gjennom en detaljert manual. Det foreligger en norsk studie som undersøker effekten av tiltaket på atferdsvansker blant barna, og foreldrepraksis og foreldrekompetanse. Studien hadde et randomisert kontrollert design med oppfølging ved oppstart, etter endt tiltak, og ved 1 og 4 år. Studien er av god forskningsmetodisk kvalitet. DUÅ Universal synes å gi en umiddelbar bedring i begynnende tegn på atferdsvansker ved endt tiltak, sammenlignet med kontrollgruppen. Det er ingen forskjell ved oppfølging på 1 og 4 år, men kan forstås slik at DUÅ Universal gir en raskere bedring for barna. Oppfølgingsstudien har dokumentert vedvarende effekt på positiv oppdragelsespraksis blant foreldrene over 4 årsperioden. Foreldrene i tiltaksgruppen rapporterte også gjennomgående om mindre bruk av røffe disiplineringsstrategier ved de enkelte måletidspunktene. I tillegg viste studien økt tilfredshet blant foreldre i foreldrerollen ved endt tiltak og 1 år, og mestringsfølelse ved endt tiltak og 4 år. Det er ikke undersøkt effekter på andre sentrale utfallsmål for programmet slik som barnas sosiale og emosjonelle kompetanse. Tiltaket vurderes å ha tilfredsstillende systemer for å sikre implementeringskvalitet.

KONKLUSJON
Basert på Ungsinn sine kriterier klassifiseres DUÅ Universal på evidensnivå 4 &ndash; tilfredsstillende dokumentasjon på effekt. Dette til tross for at det mangler langtidseffekter for det som er hovedmålsettingene med programmet for barna.
AU  - Drozd,
AU  - F.,
AU  - Lenert,
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
N1  - publishedVersion,BAKGRUNN Denne artikkelen er en kunnskapsoppsummering av effektene på De Utrolige Årenes universalprogram Oppmerksomme og utviklingsstøttende foreldre (DUÅ Universal) i Norden. DUÅ Universal er et universalforebyggende program som gis til foreldre, for å forebygge atferdsvansker og styrke sosial og emosjonell kompetanse hos barn i alderen 2 til 6 år. Regionalt kunnskapssenter for barn og unge &ndash; Nord (RKBU Nord), er tiltaksleverandør i Norge og har det nasjonale ansvaret for å gi opplæring i programmet. DUÅ Universal er et av flere programmer i DUÅs programserie som er opprinnelig utviklet i USA (www.incredibleyears.com). METODE DUÅ Universal er vurdert og klassifisert i henhold til Ungsinn sine kriterier og prosedyrer for beskrivelse av tiltaket, samt en oppsummering av effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Det ble gjort litteratursøk i databasene Embase, Medline og Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS og SweMed. Søket resulterte i tre artikler basert på en norsk effektstudie som ble inkludert. I tillegg er det innhentet informasjon om DUÅ Universal gjennom dokumentasjon fra tiltaksleverandør (deriblant manual, veiledere og annet materiell). Denne kunnskapsoppsummeringen er begrenset til det universalforebyggende tiltaket. RESULTATER DUÅ Universal er godt beskrevet i flere dokumenter blant annet gjennom en detaljert manual. Det foreligger en norsk studie som undersøker effekten av tiltaket på atferdsvansker blant barna, og foreldrepraksis og foreldrekompetanse. Studien hadde et randomisert kontrollert design med oppfølging ved oppstart, etter endt tiltak, og ved 1 og 4 år. Studien er av god forskningsmetodisk kvalitet. DUÅ Universal synes å gi en umiddelbar bedring i begynnende tegn på atferdsvansker ved endt tiltak, sammenlignet med kontrollgruppen. Det er ingen forskjell ved oppfølging på 1 og 4 år, men kan forstås slik at DUÅ Universal gir en raskere bedring for barna. Oppfølgingsstudien har dokumentert vedvarende effekt på positiv oppdragelsespraksis blant foreldrene over 4 årsperioden. Foreldrene i tiltaksgruppen rapporterte også gjennomgående om mindre bruk av røffe disiplineringsstrategier ved de enkelte måletidspunktene. I tillegg viste studien økt tilfredshet blant foreldre i foreldrerollen ved endt tiltak og 1 år, og mestringsfølelse ved endt tiltak og 4 år. Det er ikke undersøkt effekter på andre sentrale utfallsmål for programmet slik som barnas sosiale og emosjonelle kompetanse. Tiltaket vurderes å ha tilfredsstillende systemer for å sikre implementeringskvalitet. KONKLUSJON Basert på Ungsinn sine kriterier klassifiseres DUÅ Universal på evidensnivå 4 &ndash; tilfredsstillende dokumentasjon på effekt. Dette til tross for at det mangler langtidseffekter for det som er hovedmålsettingene med programmet for barna.,BACKGROUND This article is a systematic review of the effects of the Incredible Years (IY) universal prevention program Attentive Parenting in the Nordic countries. IY Attentive Parenting is a program provided to parents to prevent behavioral problems and strengthen social and emotional competence among children aged 2 to 6 years. The Regional Centre for Child and Youth Mental Health and Child Welfare, Northern Norway (RKBU Nord), is the purveyor of IY Attentive Parenting in Norway and has a national responsibility for providing training in the program. IY Attentive Parenting is one of several in the series of IY programs for parents and children, which was originally developed in the United States (www.incredibleyears.com). METHODS IY Attentive Parenting is evaluated and classified according to the Ungsinn criteria and procedures for describing interventions, as well as providing a summary of effect studies, quality of the research methods, and quality of implementation. A literature search was carried out in the following databases: Embase, Medline, PsychInfo, NORART, Cochrane, Cristin, NORA, SCOPUS, and SweMed. The search resulted in three articles based on one Norwegian study that were included. In addition, information about IY Attentive Parenting was obtained through documentation provided by the program purveyor (including a manual and other materials). RESULTS IY Attentive Parenting is well-described in several documents, including a detailed manual. There is one Norwegian study which has examined the effects of the program on child behavior problems, parenting practices and parental sense of competence. The study is a randomized controlled trial with assessments at baseline, post-treatment, 1, and 4 years follow-up, and was considered to have adequate methodological quality. IY Attentive Parenting appears to provide an improvement in symptoms of behavioral problems at post-treatment, compared to participants in the control group. There was no difference between groups during follow-up at 1 and 4 years. The effect of IY Attentive Parenting may thus be understood as providing a more rapid and immediate reduction in symptoms of behavioral problems. The long-term study documented a lasting effect on positive parenting practices over the 4-year period. Parents receiving the IY Attentive Parenting program also reported less use of harsh disciplining on individual measurement occasions. In addition, the study showed increased parenting satisfaction among parents at post-treatment and 1-year follow-up, and an increased sense of competence at post-treatment and 4-year follow-up. The study did not examine any other primary child outcomes such as social and emotional competence. IY Attentive Parenting is considered to have adequate systems to ensure the quality of implementation. CONCLUSION Despite the lack of more long-term effects on children in terms of the main program objectives, IY Attentive Parenting is classified at evidence level 4 &ndash; satisfactory evidence of efficacy.
PY  - 2019
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: De Utrolige Årene Universalprogrammet (1. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/de-utrolige-arene-universalprogrammet-1-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - **Objective** 
The aim of this study is to systematically review published studies, reporting outcomes to offspring following in utero exposure to antidepressant medications, which used an untreated depressed comparison group. 

**Methods** 
OVID, Scopus, EBSCO Collections, the Cochrane Library and Web of Science databases were searched for relevant publications published between January 1950 and May 2018 and a total of 188 potentially eligible studies were identified. 

**Results** 
Following review, 16 primary studies were eligible for inclusion. Antidepressant exposure was associated with an increased risk of lower gestational age, preterm birth, but not low birthweight or being small for gestational age compared to untreated depression. There is some evidence that congenital defects are associated with antidepressant use, particularly between cardiac defects and paroxetine use. There is conflicting evidence regarding neurodevelopment in offspring, with some reports of increased incidence of autistic spectrum disorders and depression, but also reports of no problems when measuring emotional symptoms, peer problems, conduct problems and hyperactivity-inattention scores. 

**Conclusion** 
When compared with an untreated depressed group, antidepressant exposure was associated with adverse outcomes at birth, while there is insufficient data to determine whether the association between antidepressants and congenital defects or developmental disorders is a true association. However, although we compared treated vs. untreated depression there still may be residual confounding as an untreated depressed group is likely to have less severe depression.
AN  - WOS:000496572300001
AU  - Fitton,
AU  - C.
AU  - A.
AU  - Steiner,
AU  - M.
AU  - F.
AU  - C.
AU  - Aucott,
AU  - L.
AU  - Pell,
AU  - J.
AU  - P.
AU  - Mackay,
AU  - D.
AU  - F.
AU  - Fleming,
AU  - M.
AU  - McLay,
AU  - J.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/acps.13120
L1  - internal-pdf://3159379196/Fitton_et_al-2019-Acta_Psychiatrica_Scandinavi.pdf
N1  - Fitton, C. A. Steiner, M. F. C. Aucott, L. Pell, J. P. Mackay, D. F. Fleming, M. McLay, J. S.1600-0447
PY  - 2019
T2  - Acta Psychiatrica Scandinavica
TI  - In utero exposure to antidepressant medication and neonatal and child outcomes: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000496572300001
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/acps.13120
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Attention deficit hyperactivity disorder (ADHD) which is characterized by developmentally inappropriate levels of attention, hyperactivity and impulsivity, is considered as the most common neurodevelopmental disorder in childhood. Physical exercise has shown to have several benefits in the improvement of children with ADHD. In this meta-analysis, we aimed to systematically show, with evidence, the impact of physical exercise on children with ADHD.

METHODS: 
Web of Science, MEDLINE, EMBASE, Google Scholar, Cochrane Central and http://www.ClinicalTrials.gov were the searched sources for studies which were based on the impact of physical exercise on children with ADHD. Relevant endpoints were assessed. This evidence based meta-analysis was carried out by the most relevant RevMan 5.3 software. Due to the involvement of continuous data (mean and standard deviation), weight mean difference (WMD) with 95% confidence intervals (CI) were used to represent the final analysis. A significant level of P &lt;= .05 was set and a fixed statistical effect model was used throughout the analysis.

RESULTS: 
Fourteen studies with a total number of 574 participants with ADHD were included in this evidenced based meta-analysis. Two hundred and seventy six (276) participants were assigned to the physical activity group whereas 298 participants were assigned to the control group. Results of this analysis showed that anxiety and depression were significantly improved with physical activity in these children with ADHD (WMD: -1.84; 95% CI: [-2.65 - (-1.03)], P = .00001). Hyperactive/impulsive symptoms (WMD: -0.01; 95% CI: [-0.32 - 0.29], P = .93) and inattention symptoms (WMD: -0.22; 95% CI: [-0.51 - 0.08], P = .15) were also improved with physical exercise but the results were not statistically significant. This evidence based analysis showed thought problems (WMD: -3.49; 95% CI: [-5.51 - (-1.47)], P = .0007), social problems (WMD: -5.08; 95% CI: [-7.34 - (-2.82)], P = .0001), and aggressive behaviors (WMD: -3.90; 95% CI: [-7.10 - (-0.70)], P = .02) to have significantly been improved in participants with ADHD who were assigned to physical activity group.

CONCLUSIONS: 
This current meta-analysis showed with evidence, that physical exercise has a major contribution owing to significant improvement in anxiety and depression, aggressive behaviors, thought and social problems among children suffering from ADHD. Therefore, physical exercise should be incorporated in the daily life of children with ADHD. Further future research should be able to confirm this hypothesis.
AN  - 31725664
AU  - Zang,
AU  - Y.
DA  - Nov
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1097/MD.0000000000017980
DP  - Ovid Technologies
J2  - Medicine (Baltimore)
KW  - Aggression/ph [Physiology]
KW  - Anxiety/et [Etiology]
KW  - Anxiety/th [Therapy]
KW  - Attention/ph [Physiology]
KW  - Attention Deficit Disorder with Hyperactivity/co [Complications]
KW  - Attention Deficit Disorder with Hyperactivity/pp [Physiopathology]
KW  - *Attention Deficit Disorder with Hyperactivity/th [Therapy]
KW  - Child
KW  - Depression/et [Etiology]
KW  - Depression/th [Therapy]
KW  - *Exercise/ph [Physiology]
KW  - Humans
KW  - Interpersonal Relations
KW  - Mental Health
L1  - internal-pdf://2297344609/Zang-2019.pdf
LA  - English
M3  - Meta-Analysis
N1  - Zang, Yu
PY  - 2019
SP  - e17980
T2  - Medicine
TI  - Impact of physical exercise on children with attention deficit hyperactivity disorders: Evidence through a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=31725664
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:31725664&amp;id=doi:10.1097%2FMD.0000000000017980&amp;issn=0025-7974&amp;isbn=&amp;volume=98&amp;issue=46&amp;spage=e17980&amp;pages=e17980&amp;date=2019&amp;title=Medicine&amp;atitle=Impact+of+physical+exercise+on+children+with+attention+deficit+hyperactivity+disorders%3A+Evidence+through+a+meta-analysis.&amp;aulast=Zang&amp;pid=%3Cauthor%3EZang+Y%3C%2Fauthor%3E%3CAN%3E31725664%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 98
ER  -
TY  - JOUR
AB  - **Objective** 
The current study aimed to systematically review the literature pertaining to childhood anxiety treatment, to clarify if involving both parents in cognitive behaviour therapy treatment (Parent-child CBT; PCBT) is more effective than child only treatments (Individual CBT; ICBT). 

**Method** 
PsychINFO, PubMed, Web of Science, Embase, and The Cochrane Library were searched for studies comparing child only CBT for childhood anxiety (ICBT) to CBT for the anxious child and both their parents, or CBT for the child along with some form of separate parent training or education for both the parents (PCBT). The mean age of the child participants had to be between 7 and 13 years. 

**Results** 
Five articles met inclusion criteria and compared a PCBT that had mother and father involvement to an ICBT. Two meta-analyses comparing PCBT and ICBT on the number of children free from their anxiety disorder immediately post-treatment and 1-year post-treatment follow-up were conducted. At the immediately post-treatment analysis, significant and moderate to high heterogeneity was found. No significant advantage for PCBT or ICBT was observed for either time-point analysis. Upon comparison of analyses, no significant difference between time-points for either treatment was found. 

**Conclusions** 
Results suggest that PCBT and ICBT are equally efficacious childhood anxiety treatments with no delayed effects. It is recommended that clinicians consider the need to include parents on a case-by-case basis. Future research should attempt to include both mothers and fathers in any parental interventions. The current findings are limited by the quality and methodology of the existing literature and should be considered in respect of this.
AN  - WOS:000496453000001
AU  - Carnes,
AU  - A.
AU  - Matthewson,
AU  - M.
AU  - Boer,
AU  - O.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/cp.12179
L1  - internal-pdf://1773225354/Carnes_et_al-2019-Clinical_Psychologist.pdf
N1  - Carnes, Amy Matthewson, Mandy Boer, Olivia1742-9552
PY  - 2019
SP  - 183-195
T2  - Clinical Psychologist
TI  - The contribution of parents in childhood anxiety treatment: A meta-analytic review
UR  - &lt;Go to ISI&gt;://WOS:000496453000001
UR  - https://aps.onlinelibrary.wiley.com/doi/full/10.1111/cp.12179
VL  - 23
ER  -
TY  - JOUR
AB  - **QUESTION: **
Oppositional defiant and conduct disorders (ODD and CD) start early and persist, incurring high individual and collective costs. To inform policy and practice, we therefore asked: What is the best available research evidence on preventing and treating these disorders?

**STUDY SELECTION AND ANALYSIS: **
We sought randomised controlled trials (RCTs) evaluating interventions addressing the prevention or treatment of behaviour problems in individuals aged 18 years or younger. Our criteria were tailored to identify higher-quality RCTs that were also relevant to policy and practice. We searched the CINAHL, ERIC, MEDLINE, PsycINFO and Web of Science databases, updating our initial searches in May 2017. Thirty-seven RCTs met inclusion criteria-evaluating 15 prevention programmes, 8 psychosocial treatments and 5 medications. We then conducted narrative synthesis.

**FINDINGS: **
For prevention, 3 notable programmes reduced behavioural diagnoses: Classroom-Centered Intervention; Good Behavior Game; and Fast Track. Five other programmes reduced serious behaviour symptoms such as criminal activity. Prevention benefits were long term, up to 35 years. For psychosocial treatment, Incredible Years reduced behavioural diagnoses. Three other interventions reduced criminal activity. Psychosocial treatment benefits lasted from 1 to 8years. While 4 medications reduced post-test symptoms, all caused important adverse events.

**CONCLUSIONS: **
Considerable RCT evidence favours prevention.

**CLINICAL IMPLICATIONS: **
Effective prevention programmes should therefore be made widely available. Effective psychosocial treatments should also be provided for all children with ODD/CD. But medications should be a last resort given associated adverse events and given only short-term evidence of benefits. Policymakers and practitioners can help children and populations by acting on these findings.
AD  - Waddell, Charlotte. Faculty of Health Sciences, Children&#039;s Health Policy Centre, Simon Fraser University, Vancouver, British Columbia, Canada.Schwartz, Christine. Faculty of Health Sciences, Children&#039;s Health Policy Centre, Simon Fraser University, Vancouver, British Columbia, Canada.Andres, Caitlyn. Faculty of Health Sciences, Children&#039;s Health Policy Centre, Simon Fraser University, Vancouver, British Columbia, Canada.Barican, Jenny Lou. Faculty of Health Sciences, Children&#039;s Health Policy Centre, Simon Fraser University, Vancouver, British Columbia, Canada.Yung, Donna. Faculty of Health Sciences, Children&#039;s Health Policy Centre, Simon Fraser University, Vancouver, British Columbia, Canada.
AN  - 29703717
AU  - Waddell,
AU  - C.
AU  - Schwartz,
AU  - C.
AU  - Andres,
AU  - C.
AU  - Barican,
AU  - J.
AU  - L.
AU  - Yung,
AU  - D.
DA  - 05
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/eb-2017-102862
DP  - Ovid Technologies
J2  - Evid Based Ment Health
L1  - internal-pdf://0308490235/Waddell-2018-Fifty years of preventing and tre.pdf
LA  - English
M3  - ReviewResearch Support, Non-U.S. Gov&#039;t
N1  - Waddell, CharlotteSchwartz, ChristineAndres, CaitlynBarican, Jenny LouYung, Donna
PY  - 2018
SP  - 45-52
T2  - Evidence-Based Mental Health
TI  - Fifty years of preventing and treating childhood behaviour disorders: a systematic review to inform policy and practice
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29703717
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29703717&amp;id=doi:10.1136%2Feb-2017-102862&amp;issn=1362-0347&amp;isbn=&amp;volume=21&amp;issue=2&amp;spage=45&amp;pages=45-52&amp;date=2018&amp;title=Evidence-Based+Mental+Health&amp;atitle=Fifty+years+of+preventing+and+treating+childhood+behaviour+disorders%3A+a+systematic+review+to+inform+policy+and+practice.&amp;aulast=Waddell&amp;pid=%3Cauthor%3EWaddell+C%3C%2Fauthor%3E%3CAN%3E29703717%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950520/pdf/ebmental-2017-102862.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - **OBJECTIVE:**
School refusal is an important pediatric problem with significant negative short- and long-term outcomes. Specific psychosocial treatments appear effective in reducing school refusal, but many children do not respond to these treatments. Although systematic reviews have examined the efficacy of psychological interventions for school refusal, no systematic reviews on pharmacological interventions exist.

**METHODS: **
We conducted a comprehensive literature search of MEDLINE, PsycINFO, Scopus, and Embase for randomized controlled trials (RCTs) or quasi-experimental pharmacologic trials in children and adolescents with school refusal reported in English or Spanish until July 1, 2017. Two authors screened study titles and abstracts for eligibility. Data regarding the population, intervention, comparison, and outcomes for each trial were extracted and reported. Effect sizes for school attendance are presented.

**RESULTS:**
The search identified 6 articles, including 7 trials (6 RCTs and 1 open label) and 306 youths. Pharmacologic treatments investigated for school refusal included antidepressants (imipramine, clomipramine, and fluoxetine) and benzodiazepines (alprazolam). All pharmacotherapies studied had pretreatment to posttreatment improvements on school refusal, depression, and anxiety symptoms. However, included trials were severely underpowered and did not demonstrate significant improvement compared to placebo.

**CONCLUSIONS: **
Data regarding pharmacological treatments for school refusal are sparse. Most trials in this area were conducted before development of newer antidepressants, were underpowered, and have significant methodological limitations that are characteristic of the time in which they were conducted. This systematic review highlights the need for more trials with newer pharmacologic agents, larger sample sizes, and improved systematic assessments of school refusal and comorbidities. School refusal represents an important functional outcome for many children, especially those with anxiety and depression. Future pharmacologic studies of anxiety and depression in children may benefit from incorporating specific school refusal measures as secondary outcomes.
AD  - Londono Tobon, Amalia. 1 Yale Child Study Center , New Haven, Connecticut.Londono Tobon, Amalia. 2 Yale Department of Psychiatry, Yale University , New Haven, Connecticut.Reed, Margot O. 1 Yale Child Study Center , New Haven, Connecticut.Reed, Margot O. 3 College of the Holy Cross , Worcester, Massachusetts.Taylor, Jerome H. 4 Department of Psychiatry, University of Pennsylvania , Philadelphia, Pennsylvania.Bloch, Michael H. 1 Yale Child Study Center , New Haven, Connecticut.Bloch, Michael H. 2 Yale Department of Psychiatry, Yale University , New Haven, Connecticut.
AN  - 29741917
AU  - Londono
AU  - Tobon,
AU  - A.
AU  - Reed,
AU  - M.
AU  - O.
AU  - Taylor,
AU  - J.
AU  - H.
AU  - Bloch,
AU  - M.
AU  - H.
DA  - May 09
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/cap.2017.0160
DP  - Ovid Technologies
J2  - J Child Adolesc Psychopharmacol
L1  - internal-pdf://4189590581/Londono Tobon-2018-A Systematic Review of Phar.pdf
LA  - English
N1  - Using Smart Source ParsingMayLondono Tobon, AmaliaReed, Margot OTaylor, Jerome HBloch, Michael H
PY  - 2018
SP  - 09
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - A Systematic Review of Pharmacologic Treatments for School Refusal Behavior
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29741917
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29741917&amp;id=doi:10.1089%2Fcap.2017.0160&amp;issn=1044-5463&amp;isbn=&amp;volume=&amp;issue=&amp;spage=cap&amp;pages=&amp;date=2018&amp;title=Journal+of+Child+%26+Adolescent+Psychopharmacology&amp;atitle=A+Systematic+Review+of+Pharmacologic+Treatments+for+School+Refusal+Behavior.&amp;aulast=Londono+Tobon&amp;pid=%3Cauthor%3ELondono+Tobon+A%3C%2Fauthor%3E%3CAN%3E29741917%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 09
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Prevention of substance (alcohol, tobacco, illegal/legal drug) use in adolescents is a public health priority. As the scope for school-based health education is constrained in school timetables, interventions integrating academic and health education have gained traction in the UK and elsewhere, though evidence for their effectiveness remains unclear. We sought to synthesize the effectiveness of interventions integrating academic and health education for the prevention of substance use. 

**METHODS: **
We searched 19 databases between November and December 2015, among other methods. We included randomized trials of interventions integrating academic and health education targeting school students aged 4-18 and reporting substance use outcomes. We excluded interventions for specific health-related subpopulations (e.g., children with behavioural difficulties). Data were extracted independently in duplicate. Outcomes were synthesized by school key stage (KS) using multilevel meta-analyses, for substance use, overall and by type. 

**RESULTS: **
We identified 7 trials reporting substance use. Interventions reduced substance use generally in years 7-9 (KS3) based on 5 evaluations (d = -0.09, 95% CI [-0.17, -0.01], I&lt;sup&gt;2&lt;/sup&gt; = 35%), as well as in years 10-11 (KS4) based on 3 evaluations (-0.06, [-0.09, -0.02]; I&lt;sup&gt;2&lt;/sup&gt; = 0%). Interventions were broadly effective for reducing specific alcohol, tobacco, and drug use in both KS groups. 

**CONCLUSIONS: **
Evidence quality was highly variable. Findings for years 3-6 and 12-13 could not be meta-analysed, and we could not assess publication bias. Interventions appear to have a small but significant effect reducing substance use. Specific methods of integrating academic and health education remain poorly understood.
AN  - 29446116
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Tancred,
AU  - T.
AU  - Fletcher,
AU  - A.
AU  - Thomas,
AU  - J.
AU  - Campbell,
AU  - R.
AU  - Bonell,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/cch.12558
L1  - internal-pdf://1306716022/Melendez-Torres-2018-Does integrated academic.pdf
PY  - 2018
SP  - 15
T2  - Child: Care, Health &amp; Development
TI  - Does integrated academic and health education prevent substance use? Systematic review and meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29446116
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/cch.12558
VL  - 15
ER  -
TY  - JOUR
AB  - Behavioral parent training is an evidence-based intervention that reduces child problem behavior. Unfortunately, there are notable disparities in access to and use of evidence-based parenting interventions, including BPT. One way to address the service gap is through technology-based parenting interventions. 

The purpose of this systematic review is to identify the populations targeted in technology-based parenting interventions, the effectiveness of these interventions, and areas and populations where future research is warranted. A search of three databases yielded 31 articles that met inclusion criteria. We included articles if they (a) were treatment outcome studies using web-based interventions or (b) discussed methodologies or models pertaining to web-based interventions, (c) specified demographic information such as race, ethnicity, and SES, and (d) were published in English or Spanish. 

We coded 25 treatment outcome studies and six feasibility studies. Technology-based parenting interventions have successfully improved parenting variables such as parent knowledge, behavior, and self-efficacy. Yet the vast majority of these interventions are validated with White American families and lack adaptations that may make them more accessible to underserved populations. 

As the burgeoning area of technology-based interventions continues to grow, researchers should consider underserved populations and appropriate cultural adaptations that could reduce mental health disparities and increase the scope of evidence-based interventions.
AD  - [Corralejo, Samantha M.; Rodriguez, Melanie M. Domenech] Utah State Univ, Dept Psychol, 2810 Old Main Hill, Logan, UT 84322 USA.Corralejo, SM (reprint author), Utah State Univ, Dept Psychol, 2810 Old Main Hill, Logan, UT 84322 USA.smcorralejo@gmail.corn
AN  - WOS:000440992800002
AU  - Corralejo,
AU  - S.
AU  - M.
AU  - Rodriguez,
AU  - M.
AU  - M.
AU  - D.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10826-018-1117-1
J2  - J. Child Fam. Stud.
KW  - Behavioral
KW  - Parenting
KW  - Intervention
KW  - Technology
KW  - Disparities
KW  - mental-health-care
KW  - training-program
KW  - young-children
KW  - psychological
KW  - interventions
KW  - clinical-significance
KW  - disruptive behavior
KW  - delivery
KW  - metaanalysis
KW  - childhood
KW  - disorder
KW  - Family Studies
KW  - Psychology
KW  - Psychiatry
L1  - internal-pdf://0807928496/Corralejo-2018-Technology in Parenting Program.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GP6LUTimes Cited: 0Cited Reference Count: 86Corralejo, Samantha M. Rodriguez, Melanie M. DomenechUtah State UniversityThe completion of this manuscript was supported by a Predoctoral Research Fellowship from Utah State University to the first author. The authors are grateful to Shannon Beach and Monte Cook for their skillful coding.0SpringerNew york1573-2843
PY  - 2018
SP  - 2717-2731
T2  - Journal of Child and Family Studies
TI  - Technology in Parenting Programs: A Systematic Review of Existing Interventions
UR  - &lt;Go to ISI&gt;://WOS:000440992800002
UR  - https://link.springer.com/article/10.1007%2Fs10826-018-1117-1
VL  - 27
ER  -
TY  - JOUR
AB  - Youth are inundated with media products promoting risky health behaviors (RHBs), including substance use and risky sexual activity. Media literacy interventions emphasize critical media consumption to decrease RHBs. 

However, it is unclear whether they positively influence attitudes and behavioral intentions towards RHBs. We conducted meta-analyses of 15 studies (N = 5000) testing intervention effectiveness on media literacy skills and 20 studies (N = 9177) testing effectiveness on attitudes and intentions towards RHBs. We found positive effects on media literacy skills (Hedge&#039;s g =.417, [95% CI,.29-.54]) and attitudes and intentions (Hedge&#039;s g =.100 [95% CI,.01-.19]). 

Intervention medium and target behavior moderated intervention success on attitudes and intentions, but no moderators emerged for media literacy skills. These interventions produce positive effects on media literacy skills and positive but smaller effects on attitudes and behavioral intentions, depending on medium and target behaviour. Implications for adolescent health initiatives are discussed. 

Copyright &copy; 2018 The Foundation for Professionals in Services for Adolescents
AD  - (Vahedi, Sibalis, Sutherland) Department of Psychology, Ryerson University, 350 Victoria Street, Toronto, Ontario M5B2K3, CanadaJ.E. Sutherland, Department of Psychology, Ryerson University, 350 Victoria Street, Toronto, Ontario M5B2K3, Canada. E-mail: jessica.sutherland@psych.ryerson.ca
AN  - 2000885235
AU  - Vahedi,
AU  - Z.
AU  - Sibalis,
AU  - A.
AU  - Sutherland,
AU  - J.
AU  - E.
DA  - August
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.adolescence.2018.06.007
DP  - Ovid Technologies
KW  - Adolescents
KW  - Behavioral intentions
KW  - Media literacy
KW  - Meta-analysis
KW  - Risky health behaviors
KW  - adolescent
KW  - adolescent health
KW  - female
KW  - health behavior
KW  - human
KW  - literacy
KW  - male
KW  - meta analysis
KW  - review
L1  - internal-pdf://3642569245/Vahedi-2018-Are media literacy interventions e.pdf
LA  - English
M3  - Review
PY  - 2018
SP  - 140-152
T2  - Journal of Adolescence
TI  - Are media literacy interventions effective at changing attitudes and intentions towards risky health behaviors in adolescents? A meta-analytic review
UR  - http://www.elsevier.com/inca/publications/store/6/2/2/8/4/9/index.htt
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexa&amp;AN=2000885235
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.adolescence.2018.06.007&amp;issn=0140-1971&amp;isbn=&amp;volume=67&amp;issue=&amp;spage=140&amp;pages=140-152&amp;date=2018&amp;title=Journal+of+Adolescence&amp;atitle=Are+media+literacy+interventions+effective+at+changing+attitudes+and+intentions+towards+risky+health+behaviors+in+adolescents%3F+A+meta-analytic+review&amp;aulast=Vahedi&amp;pid=%3Cauthor%3EVahedi+Z.%3C%2Fauthor%3E%3CAN%3E2000885235%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S0140197118301003/1-s2.0-S0140197118301003-main.pdf?_tid=8c8445bb-6e90-4ea4-b5ab-ed61b2ecae44&amp;acdnat=1539257307_bdbd1f386e566cc5aeee035afd2ad0af
VL  - 67
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To compare the efficacy and safety of olanzapine and risperidone in children and adolescents (aged &lt;=18 years) with psychosis by conducting a meta-analysis of randomized controlled trials (RCTs).

**METHODS: **
Several English and Chinese databases were searched for studies published before February 8th, 2017. Two independent investigators screened the studies according to prespecified criteria and extracted the data. Review Manager 5.3 was used to conduct the data synthesis.

**RESULTS: **
Eight RCTs involving 457 participants (225 participants in the olanzapine group and 232 participants in the risperidone group) were included. No significant differences were observed in the mean scores on the Positive and Negative Syndrome Scale/Brief Psychiatric Rating Scale (standard mean difference [SMD]=-0.06, 95% confidence intervals [CI]=[-0.31, 0.19], p=0.63), the positive symptom scores (SMD=-0.09, 95% CI=[-0.32, 0.15], p=0.48), or the negative symptom scores (SMD=-0.11 95% CI=[-0.34, 0.13], p=0.38) between the two groups. Regarding adverse effects, the mean increases in weight (MD=2.90, 95% CI=[1.41, 4.39], p=0.0001), body mass index (MD=0.90, 95% CI=[0.42, 1.38], p=0.0003), and incidence of hypersomnia (risk ratios [RR]=1.98, 95% CI=[1.15, 3.43], p=0.01) were higher in the olanzapine group, while the incidence of insomnia (RR=0.31, 95% CI=[0.11, 0.85], p=0.02), prolactin elevation (RR=0.11, 95% CI=[0.01, 0.85], p=0.03), myotonia (RR=0.12, 95% CI=[0.03, 0.49], p=0.003), tremor (RR=0.22, 95% CI=[0.08, 0.63], p=0.005), and akathisia (RR=0.27, 95% CI=[0.12, 0.57], p=0.0007) was higher in the risperidone group.

**CONCLUSIONS: **
There is no significant difference in efficacy between olanzapine and risperidone for the treatment of children and adolescents with psychosis, but the side effect profiles of these two medications differ. High-quality RCTs are needed before recommending clinical treatment in children and adolescents.
AD  - Xia, Lei. 1 Department of Psychiatry, Chaohu Hospital of Anhui Medical University , Hefei, China .Xia, Lei. 2 Department of Psychiatry, Anhui Psychiatric Center, Anhui Medical University , Hefei, China .Li, Wen-Zheng. 2 Department of Psychiatry, Anhui Psychiatric Center, Anhui Medical University , Hefei, China .Liu, Huan-Zhong. 1 Department of Psychiatry, Chaohu Hospital of Anhui Medical University , Hefei, China .Liu, Huan-Zhong. 2 Department of Psychiatry, Anhui Psychiatric Center, Anhui Medical University , Hefei, China .Hao, Rui. 1 Department of Psychiatry, Chaohu Hospital of Anhui Medical University , Hefei, China .Hao, Rui. 2 Department of Psychiatry, Anhui Psychiatric Center, Anhui Medical University , Hefei, China .Zhang, Xiang-Yang. 1 Department of Psychiatry, Chaohu Hospital of Anhui Medical University , Hefei, China .Zhang, Xiang-Yang. 2 Department of Psychiatry, Anhui Psychiatric Center, Anhui Medical University , Hefei, China .Zhang, Xiang-Yang. 3 Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston , Houston, Texas.
AN  - 29356569
AU  - Xia,
AU  - L.
AU  - Li,
AU  - W.
AU  - Z.
AU  - Liu,
AU  - H.
AU  - Z.
AU  - Hao,
AU  - R.
AU  - Zhang,
AU  - X.
AU  - Y.
DA  - Jan 22
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/cap.2017.0120
DP  - Ovid Technologies
J2  - J Child Adolesc Psychopharmacol
L1  - internal-pdf://2741639341/xia2018.pdf
LA  - English
N1  - Xia, LeiLi, Wen-ZhengLiu, Huan-ZhongHao, RuiZhang, Xiang-YangUsing Smart Source ParsingJan
PY  - 2018
SP  - 22
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Olanzapine Versus Risperidone in Children and Adolescents with Psychosis: A Meta-Analysis of Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29356569
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29356569&amp;id=doi:10.1089%2Fcap.2017.0120&amp;issn=1044-5463&amp;isbn=&amp;volume=&amp;issue=&amp;spage=cap&amp;pages=&amp;date=2018&amp;title=Journal+of+Child+%26+Adolescent+Psychopharmacology&amp;atitle=Olanzapine+Versus+Risperidone+in+Children+and+Adolescents+with+Psychosis%3A+A+Meta-Analysis+of+Randomized+Controlled+Trials.&amp;aulast=Xia&amp;pid=%3Cauthor%3EXia+L%3C%2Fauthor%3E%3CAN%3E29356569%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 22
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Experiences in the first 1000 days of life have a critical influence on child development and health. Health services that provide support for families need evidence about how best to improve their provision. 

**METHODS: **
We systematically reviewed the evidence for interventions in high-income countries to improve child development by enhancing health service contact with parents from the antenatal period to 24 months postpartum. We searched 15 databases and trial registers for studies published in any language between 01 January 1996 and 01 April 2016. We also searched 58 programme or organisation websites and the electronic table of contents of eight journals. 

**RESULTS: **
Primary outcomes were motor, cognitive and language development, and social-emotional well-being measured to 39 months of age (to allow the interventions time to produce demonstrable effects). Results were reported using narrative synthesis due to the variation in study populations, intervention design and outcome measurement. 22 of the 12 986 studies identified met eligibility criteria. Using Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group criteria, the quality of evidence overall was moderate to low. There was limited evidence for intervention effectiveness: positive effects were seen in 1/6 studies for motor development, 4/11 for language development, 4/8 for cognitive development and 3/19 for social-emotional well-being. However, most studies showing positive effects were at high/unclear risk of bias, within-study effects were inconsistent and negative effects were also seen. Intervention content and intensity varied greatly, but this was not associated with effectiveness. 

**CONCLUSIONS: **
There is insufficient evidence that interventions currently available to enhance health service contacts up to 24 months postpartum are effective for improving child development. There is an urgent need for robust evaluation of existing interventions and to develop and evaluate novel interventions to enhance the offer to all families. 

Prospero registration number: Crd42015015468.
AN  - 29439064
AU  - Hurt,
AU  - L.
AU  - Paranjothy,
AU  - S.
AU  - Lucas,
AU  - P.
AU  - J.
AU  - Watson,
AU  - D.
AU  - Mann,
AU  - M.
AU  - Griffiths,
AU  - L.
AU  - J.
AU  - Ginja,
AU  - S.
AU  - Paljarvi,
AU  - T.
AU  - Williams,
AU  - J.
AU  - Bellis,
AU  - M.
AU  - A.
AU  - Lingam,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmjopen-2016-014899
L1  - internal-pdf://2941511120/Hurt-2018-Interventions that enhance health se.pdf
PY  - 2018
SP  - e014899
T2  - BMJ Open
TI  - Interventions that enhance health services for parents and infants to improve child development and social and emotional well-being in high-income countries: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29439064
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829600/pdf/bmjopen-2016-014899.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - This meta-analysis evaluated the effectiveness of dialectical behavior therapy for adolescents in reducing symptoms of depression, anxiety, self-injury, and suicide risk.

Twelve between-group studies (N = 834) were chosen that met the inclusion criteria. Results revealed small-to-medium Hedges&#039;s g effect sizes for all 4 symptoms compared with control and alternative treatment groups. 

However, the small number of effect sizes available for each analysis limited the generalizability of the findings. Implications and suggestions for future research are discussed.
AD  - [Hollenbaugh, Karen Michelle Hunnicutt; Lenz, A. Stephen] Texas A&amp;M Univ, Dept Counseling &amp; Educ Psychol, 6300 Ocean Dr,ECDC 232,Unit 5834, Corpus Christi, TX 78412 USA.Hollenbaugh, KMH (reprint author), Texas A&amp;M Univ, Dept Counseling &amp; Educ Psychol, 6300 Ocean Dr,ECDC 232,Unit 5834, Corpus Christi, TX 78412 USA.michelle.hollenbaugh@tamucc.edu
AN  - WOS:000428428600001
AU  - Hollenbaugh,
AU  - K.
AU  - M.
AU  - H.
AU  - Lenz,
AU  - A.
AU  - S.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/jcad.12186
J2  - J. Couns. Dev.
KW  - dialectical behavior therapy
KW  - adolescents
KW  - meta-analysis
KW  - self-injury
KW  - suicide
KW  - self-harm
KW  - randomized-trial
KW  - eating-disorders
KW  - program
KW  - dbt
KW  - metaanalysis
KW  - community
KW  - outcomes
KW  - psychopathology
KW  - prevalence
KW  - Psychology
L1  - internal-pdf://3330737536/Hollenbaugh-2018-Preliminary Evidence for the.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: GA6FOTimes Cited: 0Cited Reference Count: 51Hollenbaugh, Karen Michelle Hunnicutt Lenz, A. Stephen05WileyHoboken1556-6676
PY  - 2018
SP  - 119-131
T2  - Journal of Counseling and Development
TI  - Preliminary Evidence for the Effectiveness of Dialectical Behavior Therapy for Adolescents
UR  - &lt;Go to ISI&gt;://WOS:000428428600001
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1002/jcad.12186
VL  - 96
ER  -
TY  - JOUR
AB  - **Background **
Low birth weight infant (LBWIs) are prone to mental and behavioural problems. As an important constituent of the brain and retina, long chain polyunsaturated fatty acids are essential for foetal infant mental and visual development. The effect of lactation supplemented with long chain polyunsaturated fatty acids (LCPUFA) on the improvement of intelligence in low birth weight children requires further validation. 

**Methods **
In this study, a comprehensive search of multiple databases was performed to identify studies focused the association between intelligence and long chain polyunsaturated fatty acid supplementation in LBWIs. Studies that compared the Bayley Scales of Infant Development (BSID) or the Wechsler Abbreviated Scale of Intelligence for Children (WISC) scores between LBWIs who were supplemented and controls that were not supplemented with LCPUFA during lactation were selected for inclusion in the meta-analysis. 

**Results **
The main outcome was the mean difference in the mental development index (MDI) and psychomotor development index (PDI) of the BSID and the full scale intelligence quotient (FSIQ), verbal intelligence quotient (VIQ) and performance intelligence quotient (PIQ) of the WISC between LBWIs and controls. Our findings indicated that the mean BSID or WISC scores in LBWIs did not differ between the supplemented groups and controls.

**Conclusion **
This meta-analysis does not reveal that LCPUFA supplementation has a significant impact on the level of intelligence in LBWIs. 

Copyright &copy; 2018 Song et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AD  - (Song, Liu, Cui) Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China (Song) Department of Gastroenterology, Jilin Province People&#039;s Hospital, Changchun, China (Pan) Tianqiao District of Ji&#039;nan Food and Drug Administration, Ji&#039;nan, Shandong Province, China (Yuan) Department of Pediatrics, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, China (Chang) Department of Radiotherapy, First Hospital of Jilin University, Changchun, China (Tian) Key Laboratory for Molecular Enzymology and Engineering of the Ministry of Education, College of Life Sciences, Jilin University, Changchun, China (Li) Department of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, China (Li) Department of Hepatology, First Hospital of Jilin University, Changchun, ChinaW. Cui, Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, China. E-mail: cuiweiwei@jlu.edu.cn
AN  - 621597422
AU  - Song,
AU  - Y.
AU  - Liu,
AU  - Y.
AU  - Pan,
AU  - Y.
AU  - Yuan,
AU  - X.
AU  - Chang,
AU  - P.
AU  - Tian,
AU  - Y.
AU  - Cui,
AU  - W.
AU  - Li,
AU  - D.
DA  - April
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0195662
DP  - Ovid Technologies
KW  - article
KW  - Bayley Scales of Infant Development
KW  - diet supplementation
KW  - human
KW  - infant
KW  - intelligence
KW  - intelligence quotient
KW  - lactation
KW  - low birth weight
KW  - mental development assessment
KW  - mental performance
KW  - meta analysis
KW  - outcome assessment
KW  - psychomotor development
KW  - Wechsler intelligence scale for children
KW  - long chain fatty acid
KW  - polyunsaturated fatty acid
L1  - internal-pdf://0249440907/Song-2018-The effect of long chain polyunsatur.pdf
LA  - English
PY  - 2018
T2  - PLoS ONE
TI  - The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0195662&amp;type=printable
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=621597422
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1371%2Fjournal.pone.0195662&amp;issn=1932-6203&amp;isbn=&amp;volume=13&amp;issue=4&amp;spage=e0195662&amp;pages=&amp;date=2018&amp;title=PLoS+ONE&amp;atitle=The+effect+of+long+chain+polyunsaturated+fatty+acid+supplementation+on+intelligence+in+low+birth+weight+infant+during+lactation%3A+A+meta-analysis&amp;aulast=Song&amp;pid=%3Cauthor%3ESong+Y.%3C%2Fauthor%3E%3CAN%3E621597422%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
VL  - 13 (4) (no pagination)
ER  -
TY  - JOUR
AB  - Children and adolescents with schizophrenia are a particularly vulnerable group. 

Thus, we integrated all the randomized evidence from the available antipsychotics used for this subgroup by performing a network-meta-analysis and pairwise meta-analysis using a random-effects model. We searched multiple databases up to Nov 17, 2016 (final update search in PubMed: Dec 12, 2017). The primary outcome was efficacy as measured by overall change/endpoint in symptoms of schizophrenia. 

Secondary outcomes included positive and negative symptoms, response, dropouts, quality of life, social functioning, weight gain, sedation, prolactin, extrapyramidal side effects (EPS) and antiparkinsonian medication. Twenty-eight randomized controlled trials (RCTs) with 3003 unique participants (58% males; mean age 14.41 years) published from 1967 to 2017 were identified. 

Clozapine was significantly more effective than all other analyzed antipsychotics. Nearly all antipsychotics were more efficacious compared to placebo, but ziprasidone showed no efficacy. In terms of preventing weight gain, molindone, lurasidone and ziprasidone were benign. The highest weight gain was found for clozapine, quetiapine and olanzapine. Most antipsychotics had some sedating effects. Risperidone, haloperidol, paliperidone and olanzapine were associated with prolactin increase. 

There were evidence gaps for some drugs and many outcomes, especially safety outcomes. Most of the comparisons are based only on one study or just on indirect evidence. Nevertheless, the available direct and indirect evidence showed that the treatment effects were similar compared to findings in adult patients with schizophrenia. 

(C) 2018 Elsevier B.V. and ECNP. All rights reserved.
AD  - [Krause, Marc; Huhn, Maximilian; Schneider-Thoma, Johannes; Bighelli, Irene; Leucht, Stefan] Tech Univ Munich, Klinikum Rechts Isar, Dept Psychiat &amp; Psychotherapy, Ismaningerstr 22, D-81675 Munich, Germany. [Zhu, Yikang] Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, Shanghai Key Lab Psychot Disorders, South Wan Ping Rd 600, Shanghai 200030, Peoples R China. [Chaimani, Anna] Paris Descartes Univ, Paris, France. [Chaimani, Anna] INSERM, Epidemiol &amp; Stat UMR1153, Sorbonne Paris Cite Res Ctr CRESS, METHODS Team, Paris, France. [Chaimani, Anna] Cochrane France, Paris, France. [Krause, Marc] Ludwig Maximilians Univ Munchen, Munich, Germany.Krause, M (reprint author), Tech Univ Munich, Klinikum Rechts Isar, Dept Psychiat &amp; Psychotherapy, Ismaningerstr 22, D-81675 Munich, Germany.marc.krause@tum.de
AN  - WOS:000436626900001
AU  - Krause,
AU  - M.
AU  - Zhu,
AU  - Y.
AU  - K.
AU  - Huhn,
AU  - M.
AU  - Schneider-Thoma,
AU  - J.
AU  - Bighelli,
AU  - I.
AU  - Chaimani,
AU  - A.
AU  - Leucht,
AU  - S.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.euroneuro.2018.03.008
J2  - Eur. Neuropsychopharmacol.
KW  - Antipsychotics
KW  - Schizophrenia
KW  - Children
KW  - Meta-analysis
KW  - Systematic
KW  - review
KW  - Efficacy
KW  - childhood-onset schizophrenia
KW  - multiple-treatments metaanalysis
KW  - paliperidone extended-release
KW  - randomized controlled-trials
KW  - placebo-controlled trial
KW  - double-blind
KW  - spectrum disorders
KW  - 2nd-generation antipsychotics
KW  - haloperidol
KW  - risperidone
KW  - Neurosciences &amp; Neurology
KW  - Pharmacology &amp; Pharmacy
KW  - Psychiatry
L1  - internal-pdf://3404924788/Krause-2018-Efficacy, acceptability, and toler.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GL0BKTimes Cited: 0Cited Reference Count: 79Krause, Marc Zhu, Yikang Huhn, Maximilian Schneider-Thoma, Johannes Bighelli, Irene Chaimani, Anna Leucht, StefanHuhn, Maximilian/0000-0003-4011-1189; Krause, Marc/0000-0002-6125-1466German Federal Ministry of Education and Research (Bundesministerium fur Bildung und Forschung, BMBF) [FKZ 01KG1508]This work was supported by a grant from the German Federal Ministry of Education and Research (Bundesministerium fur Bildung und Forschung, BMBF, Grant number: FKZ 01KG1508).0Elsevier science bvAmsterdam1873-7862
PY  - 2018
SP  - 659-674
T2  - European Neuropsychopharmacology
TI  - Efficacy, acceptability, and tolerability of antipsychotics in children and adolescents with schizophrenia: A network meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000436626900001
UR  - https://ac.els-cdn.com/S0924977X18300713/1-s2.0-S0924977X18300713-main.pdf?_tid=c2a54a9c-b8d5-478e-b6e0-1f51e93163b1&amp;acdnat=1533218752_e67a44ad1a41af9c6934701f0a5393ee
VL  - 28
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The efficacy of meditation-based therapies for attention deficit/hyperactivity disorder (ADHD) across the lifespan remains uncertain.

**OBJECTIVE: **
To conduct a systematic review and meta-analysis of randomised controlled trials (RCTs) assessing the efficacy of meditation-based therapies for ADHD core symptoms and associated neuropsychological dysfunctions in children/adolescents or adults with ADHD.

**METHODS:**
We searched Pubmed, PsycInfo, Embase+Embase Classic, Ovid Medline and Web of Knowledge with no language, date or type of document restriction, up to 5 May 2018. Random-effects model was used. Heterogeneity was assessed with Cochran&#039;s Q and I&lt;sup&gt;2&lt;/sup&gt; statistics. Publication (small studies) bias was assessed with funnel plots and the Egger&#039;s test. Studies were evaluated with the Cochrane risk of bias (RoB) tool. Analyses were conducted using Comprehensive Meta-Analysis.

**FINDINGS: **
13 RCTs (seven in children/adolescents, n=270 and six in adults, n=339) were retained. Only one RCT was double-blind.Meditation-based therapies were significantly more efficacious than the control conditions in decreasing the severity of ADHD core symptoms (inattention+hyperactivity/impulsivity: children/adolescents: Hedge&#039;s g=-0.44, 95% CI -0.69 to -0.19, I&lt;sup&gt;2&lt;/sup&gt;0%; adults: Hedge&#039;s g=-0.66, 95% CI -1.21 to -0.11, I&lt;sup&gt;2&lt;/sup&gt;81.81%). No significant effects were found on neuropsychological measures of inattention and inhibition in children/adolescents. In adults, significant effects were detected on working memory and inhibition, although these results were based on a small number of studies (n=3). 57% and 43% of the studies in children/adolescents were rated at overall unclear and high risk of bias, respectively. In adults, 33% and 67% of the studies were deemed at overall unclear and high risk of bias, respectively. No evidence of publication bias was found.

**CONCLUSIONS: **
Despite statistically significant effects on ADHD combined core symptoms, due to paucity of RCTs, heterogeneity across studies and lack of studies at low risk of bias, there is insufficient methodologically sound evidence to support meditation-based therapies for ADHD.

Trial registration number: Prospero 2018 [crd42018096156].
AD  - Zhang, Junhua. School of Education, Jiangsu Key Laboratory for Big Data of Psychology and Cognitive Science, Yancheng Teachers University, Yancheng, China.Zhang, Junhua. Center for Innovation in Mental Health, Academic Unit of Psychology, University of Southampton, Southampton, UK.Diaz-Roman, Amparo. Mind, Brain and Behavior Research Center, University of Granada, Granada, Spain.Cortese, Samuele. Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK.Cortese, Samuele. Solent NHS Trust, Southampton, UK.Cortese, Samuele. New York University Child Study Center, New York City, New York, USA.Cortese, Samuele. Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, UK.
AN  - 29991532
AU  - Zhang,
AU  - J.
AU  - Diaz-Roman,
AU  - A.
AU  - Cortese,
AU  - S.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/ebmental-2018-300015
DP  - Ovid Technologies
J2  - Evid Based Ment Health
L1  - internal-pdf://3685234993/Zhang-2018-Meditation-based therapies for atte.pdf
LA  - English
N1  - Zhang, JunhuaDiaz-Roman, AmparoCortese, Samuele
PY  - 2018
SP  - 87-94
T2  - Evidence-Based Mental Health
TI  - Meditation-based therapies for attention-deficit/hyperactivity disorder in children, adolescents and adults: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29991532
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29991532&amp;id=doi:10.1136%2Febmental-2018-300015&amp;issn=1362-0347&amp;isbn=&amp;volume=21&amp;issue=3&amp;spage=87&amp;pages=87-94&amp;date=2018&amp;title=Evidence-Based+Mental+Health&amp;atitle=Meditation-based+therapies+for+attention-deficit%2Fhyperactivity+disorder+in+children%2C+adolescents+and+adults%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Zhang&amp;pid=%3Cauthor%3EZhang+J%3C%2Fauthor%3E%3CAN%3E29991532%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://ebmh.bmj.com/content/ebmental/21/3/87.full.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - Adoption requires thorough preparations prior to the arrival of the child and support post-adoption among parents, to promote a positive parent-child relationship and healthy family functioning. 

The purpose of our study was, therefore, to systematically review the literature on pre- and post-adoption interventions for caregivers, and determine the possibility for conducting a meta-analysis. We searched 12 electronic databases and identified 7574 references that were considered for inclusion by two independent raters. 

Articles meeting the following criteria were retrieved in full-text; studies that examined the effects of (a) a pre- and/or post-adoption intervention, (b) against a comparator (including quasi-experimental studies), and (c) report on outcomes for parents. 

Finally, we included 10 studies that met our inclusion criteria and which were assessed in terms of reported intervention effects and study quality using Cochrane&#039;s Risk of Bias tool. All studies were associated with a high risk of bias in at least one out of seven domains and unclear reporting on several domains. Eight studies examined intervention effects related to interpersonal functioning; three of which found positive effects. 

In addition, three studies investigated effects on parenting and stress, respectively; however, only one study demonstrated effects on parenting and none on parental stress. Overall, the study designs, interventions, and results were characterized by substantial heterogeneity, making a meta-analysis unfeasible. In conclusion, the results from the included studies in our review does not point in any particular direction. 

The most consistent finding across studies was the lack of studies on pre-adoption interventions, and poor design and unclear reporting. Consequently, future studies should evaluate pre-adoption interventions, and need to use more rigorous design, transparent and comprehensible reporting, as well as more homogenous interventions and methods, to move the field forward in support of adoptive parents.
AN  - WOS:000424217300001
AU  - Drozd,
AU  - F.
AU  - Bergsund,
AU  - H.
AU  - B.
AU  - Hammerstrom,
AU  - K.
AU  - T.
AU  - Hansen,
AU  - M.
AU  - B.
AU  - Jacobsen,
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10826-017-0901-7
L1  - internal-pdf://2420176803/Drozd-2018-A Systematic Review of Courses, Tra.pdf
PY  - 2018
SP  - 339-354
T2  - Journal of Child and Family Studies
TI  - A Systematic Review of Courses, Training, and Interventions for Adoptive Parents
UR  - &lt;Go to ISI&gt;://WOS:000424217300001
UR  - https://link.springer.com/article/10.1007%2Fs10826-017-0901-7
UR  - https://link.springer.com/content/pdf/10.1007%2Fs10826-017-0901-7.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - Prenatal alcohol exposure results in cognitive, behavioral, and neurological deficits in offspring. There is an urgent need for safe and effective treatments to overcome these effects. Maternal choline supplementation has been identified as a potential intervention. 

Our objective was to review preclinical and clinical studies using choline supplementation in known cases of fetal alcohol exposure to determine its effectiveness in ameliorating deficits in offspring. 

A systematic search of 6 electronic databases was conducted and studies selected by reviewing titles/abstracts against specific inclusion/exclusion criteria. Study characteristics, population demographics, alcohol exposure, and intervention methods were tabulated, and quality of reporting was assessed. Data on cognitive, behavioral, and neurological outcomes were extracted and tabulated. Quantitative analysis was performed to determine treatment effects for individual study outcomes. 

A total of 189 studies were retrieved following duplicate removal. Of these, 22 studies (2 randomized controlled trials, 2 prospective cohort studies, and 18 preclinical studies) met the full inclusion/exclusion criteria. 

Choline interventions were administered at different times relative to alcohol exposure, impacting on their success to prevent deficits for specific outcomes. Only 1 clinical study showed significant improvements in information processing in 6-month-old infants from mothers treated with choline during pregnancy. 

Preclinical studies showed significant amelioration of deficits due to prenatal alcohol exposure across a wide variety of outcomes, including epigenetic/molecular changes, gross motor, memory, and executive function.

This review suggests that choline supplementation has the potential to ameliorate specific behavioral, neurological, and cognitive deficits in offspring caused by fetal alcohol exposure, at least in preclinical studies. 

As only 1 clinical study has shown benefit, we recommend more clinical trials be undertaken to assess the effectiveness of choline in preventing deficits across a wider range of cognitive domains in children.
AD  - [Akison, Lisa K.; Kuo, Jenny; Moritz, Karen M.] Univ Queensland, Sch Biomed Sci, St Lucia, Qld, Australia. [Akison, Lisa K.; Reid, Natasha; Boyd, Roslyn N.; Moritz, Karen M.] Univ Queensland, Child Hlth Res Ctr, South Brisbane, Qld, Australia. [Boyd, Roslyn N.] Univ Queensland, Queensland Cerebral Palsy &amp; Rehabil Res Ctr, Child Hlth Res Ctr, Ctr Childrens Hlth Res, South Brisbane, Qld, Australia.Akison, LK (reprint author), Univ Queensland, Child Hlth Res Ctr, Ctr Childrens Hlth Res, Room 408,62 Graham St, South Brisbane, Qld 4101, Australia.l.akison@uq.edu.au
AN  - WOS:000443378800003
AU  - Akison,
AU  - L.
AU  - K.
AU  - Kuo,
AU  - J.
AU  - Reid,
AU  - N.
AU  - Boyd,
AU  - R.
AU  - N.
AU  - Moritz,
AU  - K.
AU  - M.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/acer.13817
J2  - Alcoholism (NY)
KW  - Fetal Alcohol Exposure
KW  - Choline Supplementation
KW  - Maternal Nutrition
KW  - Fetal Development
KW  - Fetal Alcohol Spectrum Disorder
KW  - fetal alcohol
KW  - spectrum disorders
KW  - neonatal ethanol
KW  - DNA methylation
KW  - neurodevelopmental impairment
KW  - prenatal exposure
KW  - animal research
KW  - gut
KW  - microbiota
KW  - brain growth
KW  - double-blind
KW  - Substance Abuse
L1  - internal-pdf://0335869782/Akison-2018-Effect of Choline Supplementation.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GS2KXTimes Cited: 0Cited Reference Count: 95Akison, Lisa K. Kuo, Jenny Reid, Natasha Boyd, Roslyn N. Moritz, Karen M.Boyd, Roslyn/A-4498-2011Boyd, Roslyn/0000-0002-4919-5975; Reid, Natasha/0000-0001-9813-5613; Akison, Lisa/0000-0002-2667-3743National Health and Medical Research Council (NHMRC); Children&#039;s Health Research Centre (CHRC), the University of QueenslandNational Health and Medical Research Council (NHMRC) for KMM and RNB; and Children&#039;s Health Research Centre (CHRC), the University of Queensland, for LKA.03WileyHoboken1530-0277
PY  - 2018
SP  - 1591-1611
T2  - Alcoholism-Clinical and Experimental Research
TI  - Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies
UR  - &lt;Go to ISI&gt;://WOS:000443378800003
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/acer.13817
VL  - 42
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Dropout is one factor that might limit the effectiveness of interpersonal psychotherapy (IPT). Improved understanding of IPT dropout is an important research priority. This meta-analysis examined dropout rates from IPT in randomized controlled trials.

**METHOD: **
Seventy-two trials met inclusion criteria.

**RESULTS: **
The weighted mean dropout rate from IPT was 20.6% (95% CI=17.4-24.2). Dropout rates were similar for depressive (20.9%; 95% CI=17.2-25.2), anxiety (16.1%; 95% CI=11.1-22.9), and eating disorders (18.7%; 95% CI=11.6-28.8). Dropout was highest when more stringent definitions of dropout were applied (e.g., failure to complete the entire IPT protocol versus failure to complete at least 50% of sessions) and was lowest when adolescent patients were sampled. There was some evidence that IPT was associated with significantly lower rates of dropout than both CBT and non-specific supportive therapies. These effects were generally replicated when analysing trials that provided a clear definition of treatment (rather than study) dropout.

**CONCLUSIONS: **
Overall, findings provide preliminary evidence to suggest that IPT may be an accepted and tolerated treatment option for patients with common mental health disorders. This review also highlights the need for future trials to rigorously report detail pertaining to patient dropout.
AD  - Linardon, Jake. a School of Psychology , Deakin University , Burwood , VIC , Australia.Fitzsimmons-Craft, Ellen E. b Department of Psychiatry , Washington University School of Medicine , St. Louis , MO , USA.Brennan, Leah. c School of Psychology , Australian Catholic University , Melbourne , VIC , Australia.Barillaro, Mary. c School of Psychology , Australian Catholic University , Melbourne , VIC , Australia.Wilfley, Denise E. b Department of Psychiatry , Washington University School of Medicine , St. Louis , MO , USA.
AN  - 30005586
AU  - Linardon,
AU  - J.
AU  - Fitzsimmons-Craft,
AU  - E.
AU  - E.
AU  - Brennan,
AU  - L.
AU  - Barillaro,
AU  - M.
AU  - Wilfley,
AU  - D.
AU  - E.
DA  - Jul 13
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/10503307.2018.1497215
DP  - Ovid Technologies
J2  - Psychother
L1  - internal-pdf://1253577187/Linardon-2018-Dropout from interpersonal psych.pdf
LA  - English
N1  - Linardon, JakeFitzsimmons-Craft, Ellen EBrennan, LeahBarillaro, MaryWilfley, Denise E
PY  - 2018
SP  - 1-12
T2  - Psychotherapy Research
TI  - Dropout from interpersonal psychotherapy for mental health disorders: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30005586
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30005586&amp;id=doi:10.1080%2F10503307.2018.1497215&amp;issn=1050-3307&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-12&amp;date=2018&amp;title=Psychotherapy+Research&amp;atitle=Dropout+from+interpersonal+psychotherapy+for+mental+health+disorders%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Linardon&amp;pid=%3Cauthor%3ELinardon+J%3C%2Fauthor%3E%3CAN%3E30005586%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/pdf/10.1080/10503307.2018.1497215?needAccess=true
ER  -
TY  - JOUR
AB  - **Background: **
The benefits and safety of medications for attention-deficit hyperactivity disorder (ADHD) remain controversial, and guidelines are inconsistent on which medications are preferred across different age groups. We aimed to estimate the comparative efficacy and tolerability of oral medications for ADHD in children, adolescents, and adults. 

**Methods: **
We did a literature search for published and unpublished double-blind randomised controlled trials comparing amphetamines (including lisdexamfetamine), atomoxetine, bupropion, clonidine, guanfacine, methylphenidate, and modafinil with each other or placebo. We systematically contacted study authors and drug manufacturers for additional information. Primary outcomes were efficacy (change in severity of ADHD core symptoms based on teachers&#039; and clinicians&#039; ratings) and tolerability (proportion of patients who dropped out of studies because of side-effects) at timepoints closest to 12 weeks, 26 weeks, and 52 weeks. We estimated summary odds ratios (ORs) and standardised mean differences (SMDs) using pairwise and network meta-analysis with random effects. We assessed the risk of bias of individual studies with the Cochrane risk of bias tool and confidence of estimates with the Grading of Recommendations Assessment, Development, and Evaluation approach for network meta-analyses. This study is registered with PROSPERO, number CRD42014008976. 

**Findings:** 
133 double-blind randomised controlled trials (81 in children and adolescents, 51 in adults, and one in both) were included. The analysis of efficacy closest to 12 weeks was based on 10 068 children and adolescents and 8131 adults; the analysis of tolerability was based on 11 018 children and adolescents and 5362 adults. The confidence of estimates varied from high or moderate (for some comparisons) to low or very low (for most indirect comparisons). For ADHD core symptoms rated by clinicians in children and adolescents closest to 12 weeks, all included drugs were superior to placebo (eg, SMD -1.02, 95% CI -1.19 to -0.85 for amphetamines, -0.78, -0.93 to -0.62 for methylphenidate, -0.56, -0.66 to -0.45 for atomoxetine). By contrast, for available comparisons based on teachers&#039; ratings, only methylphenidate (SMD -0.82, 95% CI -1.16 to -0.48) and modafinil (-0.76, -1.15 to -0.37) were more efficacious than placebo. In adults (clinicians&#039; ratings), amphetamines (SMD -0.79, 95% CI -0.99 to -0.58), methylphenidate (-0.49, -0.64 to -0.35), bupropion (-0.46, -0.85 to -0.07), and atomoxetine (-0.45, -0.58 to -0.32), but not modafinil (0.16, -0.28 to 0.59), were better than placebo. With respect to tolerability, amphetamines were inferior to placebo in both children and adolescents (odds ratio [OR] 2.30, 95% CI 1.36-3.89) and adults (3.26, 1.54-6.92); guanfacine was inferior to placebo in children and adolescents only (2.64, 1.20-5.81); and atomoxetine (2.33, 1.28-4.25), methylphenidate (2.39, 1.40-4.08), and modafinil (4.01, 1.42-11.33) were less well tolerated than placebo in adults only. In head-to-head comparisons, only differences in efficacy (clinicians&#039; ratings) were found, favouring amphetamines over modafinil, atomoxetine, and methylphenidate in both children and adolescents (SMDs -0.46 to -0.24) and adults (-0.94 to -0.29). We did not find sufficient data for the 26-week and 52-week timepoints. 

**Interpretation: **
Our findings represent the most comprehensive available evidence base to inform patients, families, clinicians, guideline developers, and policymakers on the choice of ADHD medications across age groups. Taking into account both efficacy and safety, evidence from this meta-analysis supports methylphenidate in children and adolescents, and amphetamines in adults, as preferred first-choice medications for the short-term treatment of ADHD. New research should be funded urgently to assess long-term effects of these drugs. 

**Funding: **
Stichting Eunethydis (European Network for Hyperkinetic Disorders), and the UK National Institute for Health Research Oxford Health Biomedical Research Centre. 

Copyright &copy; 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
AD  - (Cortese) Center for Innovation in Mental Health, Academic Unit of Psychology, Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, United Kingdom (Cortese) Solent NHS Trust, Southampton, United Kingdom (Cortese) New York University Child Study Center, New York, NY, United States (Cortese, Hollis) Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, United Kingdom (Adamo, Simonoff) Department of Child and Adolescent Psychiatry, King&#039;s College London, Institute of Psychiatry, Psychology and Neuroscience, National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre, London, United Kingdom (Del Giovane) Institute of Primary Health Care, University of Bern, Switzerland (Mohr-Jensen) Department of Child and Adolescent Psychiatry, Aalborg Psychiatric Hospital, Aalborg University Hospital, Aalborg, Denmark (Hayes, Atkinson, Cipriani) Department of Psychiatry, University of Oxford, Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, United Kingdom (Carucci, Zuddas) Child and Adolescent Neuropsychiatry Unit, Department of Biomedical Sciences, University of Cagliari and &quot;A Cao&quot; Paediatric Hospital, &quot;G Brotzu&quot; Hospital Trust, Cagliari, Italy (Tessari) Department of Child and Adolescent Psychiatry and Psychotherapy, Bolzano, Italy (Banaschewski) Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim and University of Heidelberg, Mannheim, Germany (Coghill) Departments of Paediatrics and Psychiatry, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Vic, Australia (Coghill) Division of Neuroscience, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom (Coghill) Murdoch Childrens&#039; Research Institute, Melbourne, Vic, Australia (Hollis) NIHR Nottingham Biomedical Research Centre, NIHR MindTech MedTech and In-vitro Diagnostic Cooperative, Centre for ADHD and Neurodevelopmental Disorders Across the Lifespan (CANDAL), Institute of Mental Health, University of Nottingham, Nottingham, United Kingdom (Barbui, Purgato) WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine, and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy (Steinhausen) Department of Child and Adolescent Psychiatry, Psychiatric University Clinic Zurich, Zurich, Switzerland (Steinhausen) Clinical Psychology and Epidemiology, Department of Psychology, University of Basel, Basel, Switzerland (Steinhausen) Child and Adolescent Mental Health Centre, Capital Region Psychiatry, Copenhagen, Denmark (Steinhausen) Department of Child and Adolescent Psychiatry, University of Southern Denmark, Odense, Denmark (Shokraneh) Cochrane Schizophrenia Group, Division of Psychiatry and Clinical Psychology, School of Medicine, University of Nottingham, Nottingham, United Kingdom (Shokraneh) Research Center for Modeling in Health, Institute for Future Studies in Health, Kerman University of Medical Sciences, Kerman, Iran, Islamic Republic of (Xia) Systematic Review Solutions, Nottingham Health China, University of Nottingham, Ningbo, ChinaA. Cipriani, Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, United Kingdom. E-mail: andrea.cipriani@psych.ox.ac.uk
AN  - 2001133135
AU  - Cortese,
AU  - S.
AU  - Adamo,
AU  - N.
AU  - Del
AU  - Giovane,
AU  - C.
AU  - Mohr-Jensen,
AU  - C.
AU  - Hayes,
AU  - A.
AU  - J.
AU  - Carucci,
AU  - S.
AU  - Atkinson,
AU  - L.
AU  - Z.
AU  - Tessari,
AU  - L.
AU  - Banaschewski,
AU  - T.
AU  - Coghill,
AU  - D.
AU  - Hollis,
AU  - C.
AU  - Simonoff,
AU  - E.
AU  - Zuddas,
AU  - A.
AU  - Barbui,
AU  - C.
AU  - Purgato,
AU  - M.
AU  - Steinhausen,
AU  - H.
AU  - C.
AU  - Shokraneh,
AU  - F.
AU  - Xia,
AU  - J.
AU  - Cipriani,
AU  - A.
DA  - September
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/S2215-0366(18)30269-4
DP  - Ovid Technologies
KW  - adolescent
KW  - adult
KW  - article
KW  - attention deficit disorder
KW  - child
KW  - clinician
KW  - comparative effectiveness
KW  - double blind procedure
KW  - drug safety
KW  - drug therapy
KW  - female
KW  - funding
KW  - groups by age
KW  - head
KW  - human
KW  - male
KW  - medical research
KW  - meta analysis
KW  - network meta analysis
KW  - oral drug administration
KW  - outcome assessment
KW  - pharmacokinetics
KW  - practice guideline
KW  - randomized controlled trial (topic)
KW  - risk assessment
KW  - short course therapy
KW  - side effect
KW  - systematic review
KW  - teacher
KW  - visually impaired person
KW  - amfebutamone
KW  - atomoxetine
KW  - clonidine
KW  - guanfacine
KW  - lisdexamfetamine
KW  - methylphenidate
KW  - modafinil
KW  - placebo
L1  - internal-pdf://3822519367/Cortese-2018-Comparative efficacy and tolerabi.pdf
LA  - English
PY  - 2018
SP  - 727-738
T2  - The Lancet Psychiatry
TI  - Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2001133135
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2FS2215-0366%252818%252930269-4&amp;issn=2215-0366&amp;isbn=&amp;volume=5&amp;issue=9&amp;spage=727&amp;pages=727-738&amp;date=2018&amp;title=The+Lancet+Psychiatry&amp;atitle=Comparative+efficacy+and+tolerability+of+medications+for+attention-deficit+hyperactivity+disorder+in+children%2C+adolescents%2C+and+adults%3A+a+systematic+review+and+network+meta-analysis&amp;aulast=Cortese&amp;pid=%3Cauthor%3ECortese+S.%3C%2Fauthor%3E%3CAN%3E2001133135%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S2215036618302694/1-s2.0-S2215036618302694-main.pdf?_tid=70e52838-99c4-4c61-9bda-f0729c598b33&amp;acdnat=1539256868_ce238ab117bdba4d82f0ac040a2e2a2d
VL  - 5
ER  -
TY  - JOUR
AB  - This article is intended to synthesize the broader literature investigating the effectiveness and salient features of interventions designed to enhance the social competence of youth and adults with autism spectrum disorder. 

Outcomes for adults with autism spectrum disorder remain poor with only minimal improvement shown for decades. Among 796 articles reviewed, 42 representative social skill intervention studies met the selection criteria and were coded descriptively for design elements and findings. 

The review synthesizes and classifies the major categories and issues associated with the key features of the intervention (e.g., the intervention method, agent, tools, and measures), nature of the learning tasks, the implementation setting and length, research methodology, and key findings related to social competence.
AN  - WOS:000419873400001
AU  - Ke,
AU  - F.
AU  - Whalon,
AU  - K.
AU  - Yun,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3102/0034654317740334
L1  - internal-pdf://2206177935/Ke-2018-Social Skill Interventions for Youth a.pdf
PY  - 2018
SP  - 3-42
T2  - Review of Educational Research
TI  - Social Skill Interventions for Youth and Adults With Autism Spectrum Disorder: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000419873400001
UR  - http://journals.sagepub.com/doi/10.3102/0034654317740334
UR  - http://journals.sagepub.com/doi/pdf/10.3102/0034654317740334
VL  - 88
ER  -
TY  - JOUR
AB  - **Background and aims**
Whole‐of‐community interventions aim to reduce alcohol and other drug (AOD) use and harms by mobilizing community leaders, organizations and policy‐makers to respond effectively to AOD use. The aim of this review is to estimate the effectiveness of whole‐of‐community interventions in reducing population‐level harms arising from AOD use.

**Design**
A systematic review of electronic databases CENTRAL, Embase, Medline, Medline in Process and PsycINFO was conducted from database inception to August 2017. Eligible trials had a parallel comparison group, implemented interventions in two or more community settings, and reported data on AOD use or harms.

**Setting**
Intervention settings included schools, sporting clubs, police and law enforcement agencies, community centres, local media and retail premises.

**Participants**
Twenty‐four trials from 63 publications were included (n = 249&thinsp;125 participants).

**Measurements**
Outcomes from AOD consumption (quantity and frequency), AOD‐related crime and AOD‐related accidents, injuries and hospital admissions. Data were pooled using random‐effects inverse variance meta‐analysis in Review Manager version 5.3.

**Findings**
Risk of bias was mostly high, due to lack of random allocation, selective reporting and significant attrition. Meta‐analyses indicated significant reductions in risky drinking [Alcohol Use Disorders Identification Scale (AUDIT) &gt; 8; three trials (7 data points), relative risk (RR) = 0.78, 95% confidence interval (CI) = 0.62&ndash;0.99)], but found no impact on past‐month alcohol use (five trials, RR = 0.95, 95% CI = 0.89&ndash;1.02), binge drinking (five trials, RR = 0.97, 95% CI = 0.89&ndash;1.06) or 12‐month marijuana use (two trials, RR = 0.98, 95% CI = 0.86&ndash;1.11). Narrative synthesis indicated some reductions in AOD‐related assault rates and arrests, but were equivocal for quantity of alcohol consumed, 12‐month illicit drug use, assault or abuse, motor vehicle accidents and hospital admissions.

**Conclusions**
Interventions to reduce alcohol and other drug use and harms applied to whole communities have resulted so far in small reductions in risky alcohol consumption, but have had little impact upon past month alcohol use, binge drinking or 12‐month marijuana use and the studies have been subject to high risk of bias.
AD  - [Stockings, Emily] UNSW Sydney, Natl Drug &amp; Alcohol Res Ctr, Randwick, NSW, Australia. [Bartlem, Kate; Hall, Alix; Hodder, Rebecca; Gilligan, Conor; Wiggers, John; Wolfenden, Luke] HNEPH, Wallsend, NSW, Australia. [Bartlem, Kate] Univ Newcastle, Sch Psychol, Callaghan, NSW, Australia. [Hall, Alix; Hodder, Rebecca; Gilligan, Conor; Wiggers, John; Sherker, Shauna; Wolfenden, Luke] Univ Newcastle, Sch Med &amp; Publ Hlth, Callaghan, NSW, Australia. [Hall, Alix; Hodder, Rebecca; Gilligan, Conor; Wiggers, John; Wolfenden, Luke] Hunter Med Res Inst, New Lambton Hts, NSW, Australia. [Sherker, Shauna] Alcohol &amp; Drug Fdn, North Melbourne, Vic, Australia.Stockings, E (reprint author), UNSW Australia, Natl Drug &amp; Alcohol Res Ctr, 22-32 King St, Randwick, NSW 2031, Australia.e.stockings@unsw.edu.au
AN  - WOS:000446549800004
AU  - Stockings,
AU  - E.
AU  - Bartlem,
AU  - K.
AU  - Hall,
AU  - A.
AU  - Hodder,
AU  - R.
AU  - Gilligan,
AU  - C.
AU  - Wiggers,
AU  - J.
AU  - Sherker,
AU  - S.
AU  - Wolfenden,
AU  - L.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/add.14277
J2  - Addiction
KW  - Alcohol use
KW  - community intervention
KW  - early intervention
KW  - harm reduction
KW  - prevention
KW  - substance use
KW  - substance-use
KW  - prevention trial
KW  - use disorders
KW  - global health
KW  - outcomes
KW  - project
KW  - program
KW  - abuse
KW  - adolescents
KW  - consumption
KW  - Substance Abuse
KW  - Psychiatry
L1  - internal-pdf://1954001005/Stockings-2018-Whole-of-community intervention.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GW0JLTimes Cited: 0Cited Reference Count: 56Stockings, Emily Bartlem, Kate Hall, Alix Hodder, Rebecca Gilligan, Conor Wiggers, John Sherker, Shauna Wolfenden, LukeStockings, Emily/0000-0001-5349-951XAlcohol and Drug Foundation; Australian National Health and Medical Research Council (NHMRC); Australian Government under Substance Misuse Prevention and Service Improvements Grant FundThis work received funding from the Alcohol and Drug Foundation. E.S., L.W. and K.B. are funded by Australian National Health and Medical Research Council (NHMRC) fellowships. The National Drug and Alcohol Research Centre at the University of NSW is supported by funding from the Australian Government under the Substance Misuse Prevention and Service Improvements Grant Fund. The authors would like to acknowledge Professor Anthony Shakeshaft at the National Drug and Alcohol Research Centre, University of New South Wales, for his expert input during the conduct of this review and preparation of the manuscript, and Debbie Booth, Senior Research Librarian from the University of Newcastle for assisting with the literature searches.0WileyHoboken1360-0443
PY  - 2018
SP  - 1984-2018
T2  - Addiction
TI  - Whole-of-community interventions to reduce population-level harms arising from alcohol and other drug use: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000446549800004
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/add.14277
VL  - 113
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
Poor maternal mental health during the perinatal period has been shown to have potentially long-lasting effects for mother and child. In recognition of this, maternal mental health is receiving increased attention from political and healthcare organizations, with a growing focus on preventing the onset of common mental health disorders.

**OBJECTIVE: **
The objective for this review is to provide an update of randomized controlled trials examining the use of interventions targeted to prevent the onset of postnatal depression and anxiety in nondiagnostic populations with universal or selected samples.

**METHODS: **
A total of four databases, EBSCO Host, Science Direct, Scopus, and Web of Science, incorporating PsychINFO were searched and papers selected according to clearly specified inclusion criteria. A large Health Technology review was published in 2016, for which the final search was conducted in December 2012. Therefore inclusion criteria were studies published from January 2013 onwards, available in English language, had a focus on prevention of postnatal maternal depression and anxiety, and used psychological interventions. Drug intervention trials were excluded.

**FINDINGS: **
12 studies were identified as examining antenatal or postnatal intervention trials with an aim of preventing maternal postnatal depression and/or anxiety. There continues to be limited evidence to recommend specific prevention strategies for universal samples without further testing. There is evidence to suggest the use of rational-emotive behavioral therapy in an antenatal sample may have some utility, and the use of psychotherapy-based interventions in a postnatal setting is also supported although both require further investigation. Additionally, there is a need to gather information on acceptability, as many trials were hindered by poor adherence to interventions and high attrition that were otherwise unexplained.
AD  - Mahdi, Amy. a NHS Foundation Trust , Liverpool Women&#039;s Hospital , Liverpool , UK.Dembinsky, Melanie. b Institute of Psychology Health and Society , University of Liverpool , Liverpool , UK.Bristow, Katie. b Institute of Psychology Health and Society , University of Liverpool , Liverpool , UK.Bristow, Katie. c Improving Mental Health, NIHR CLAHRC North West Coast , University of Liverpool , Liverpool , UK.Slade, Pauline. b Institute of Psychology Health and Society , University of Liverpool , Liverpool , UK.
AN  - 30204522
AU  - Mahdi,
AU  - A.
AU  - Dembinsky,
AU  - M.
AU  - Bristow,
AU  - K.
AU  - Slade,
AU  - P.
DA  - Sep 11
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/0167482X.2018.1512577
DP  - Ovid Technologies
J2  - J Psychosom Obstet Gynaecol
L1  - internal-pdf://1328944493/Mahdi-2018-Approaches to the prevention of pos.pdf
LA  - English
N1  - Mahdi, AmyDembinsky, MelanieBristow, KatieSlade, Pauline
PY  - 2018
SP  - 1-14
T2  - Journal of Psychosomatic Obstetrics &amp; Gynecology
TI  - Approaches to the prevention of postnatal depression and anxiety - a review of the literature
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30204522
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30204522&amp;id=doi:10.1080%2F0167482X.2018.1512577&amp;issn=0167-482X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-14&amp;date=2018&amp;title=Journal+of+Psychosomatic+Obstetrics+%26+Gynecology&amp;atitle=Approaches+to+the+prevention+of+postnatal+depression+and+anxiety+-+a+review+of+the+literature.&amp;aulast=Mahdi&amp;pid=%3Cauthor%3EMahdi+A%3C%2Fauthor%3E%3CAN%3E30204522%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/pdf/10.1080/0167482X.2018.1512577?needAccess=true
ER  -
TY  - JOUR
AB  - Efficacy of EMDR and TF-CBT for posttraumatic stress symptoms (PTSS) was explored through meta-analysis. 

A comprehensive search yielded 494 studies of children and adolescents with PTSS who received treatment with these evidence-based therapeutic modalities. Thirty total studies were included in the meta-analysis. 

The overall Cohen&#039;s d was small (-0.359) and statistically significant (p &lt; 0.05), indicating EMDR and TF-CBT are effective in treating PTSS. 

Major findings posit TF-CBT is marginally more effective than EMDR; those with sub-clinical PTSS responded more favorably in treatment than those with PTSD; and greater reductions in PTSS were observed with presence of comorbidity in diagnosis.

Assessment of publication bias with Classic fail-safe N revealed it would take 457 nonsignificant studies to nullify these findings. 

Copyright &copy; 2018, Springer International Publishing AG, part of Springer Nature.
AN  - 625090802
AU  - Lewey,
AU  - J.
AU  - H.
AU  - Smith,
AU  - C.
AU  - L.
AU  - Burcham,
AU  - B.
AU  - Saunders,
AU  - N.
AU  - L.
AU  - Elfallal,
AU  - D.
AU  - O&#039;Toole,
AU  - S.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s40653-018-0212-1
L1  - internal-pdf://1401686323/Lewey-2018-Comparing the Effectiveness of EMDR.pdf
PY  - 2018
SP  - 457-472
T2  - Journal of Child and Adolescent Trauma
TI  - Comparing the Effectiveness of EMDR and TF-CBT for Children and Adolescents: a Meta-Analysis
UR  - http://www.springer.com/psychology/child+%26+school+psychology/journal/40653
UR  - https://link.springer.com/article/10.1007%2Fs40653-018-0212-1
VL  - 11
ER  -
TY  - JOUR
AB  - In the youth treatment literature, the alliance has been defined and measured as a consensual or collaborative bond. In this article, we review varied definitions of the alliance, enumerate its frequent measures, and present clinical examples. 

We provide a meta-analytic review on the relation between the therapeutic alliance and treatment outcome in child and adolescent psychotherapy. In particular, this review only includes prospective studies of youth therapy that used an explicit measure of alliance. 

The meta-analysis of 28 studies revealed a weighted random effect size of r = .19 (k = 28, N = 2419, p &lt; .01, 95% confidence interval [.13, .25]), which is a small to medium effect (equivalent to d = 0.39) consistent with the adult alliance literature and with prior youth meta-analyses. Given that a medium-large amount of heterogeneity was observed in effect sizes (I2 = 64.19%), theory- and method-based moderators were examined. 

Multiple moderators of the alliance-outcome association were found, including diagnosis class, type of therapy, study design (randomized controlled trials [RCT] vs. nonrandomized trials [non-RCT]), and treatment setting (inpatient vs. outpatient). Research limitations, patient contributions, and diversity considerations follow. 

The article concludes with research-informed practices for building and maintaining the therapeutic alliance with youth. 

(PsycINFO Database Record (c) 2018 APA, all rights reserved).
AD  - Karver, Marc S. Department of Psychology, University of South Florida.De Nadai, Alessandro S. Department of Psychology, Texas State University.Monahan, Maureen. Department of Psychology, University of South Florida.Shirk, Stephen R. Department of Psychology, University of Denver.
AN  - 30335449
AU  - Karver,
AU  - M.
AU  - S.
AU  - De
AU  - Nadai,
AU  - A.
AU  - S.
AU  - Monahan,
AU  - M.
AU  - Shirk,
AU  - S.
AU  - R.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/pst0000176
DP  - Ovid Technologies
J2  - Psychotherapy
L1  - internal-pdf://1035052963/Karver-2018-Meta-analysis of the prospective r.pdf
LA  - English
N1  - Karver, Marc SDe Nadai, Alessandro SMonahan, MaureenShirk, Stephen R
PY  - 2018
SP  - 341-355
T2  - Psychotherapy: Theory, Research, Practice, Training
TI  - Meta-analysis of the prospective relation between alliance and outcome in child and adolescent psychotherapy
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30335449
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30335449&amp;id=doi:10.1037%2Fpst0000176&amp;issn=0033-3204&amp;isbn=&amp;volume=55&amp;issue=4&amp;spage=341&amp;pages=341-355&amp;date=2018&amp;title=Psychotherapy%3A+Theory%2C+Research%2C+Practice%2C+Training&amp;atitle=Meta-analysis+of+the+prospective+relation+between+alliance+and+outcome+in+child+and+adolescent+psychotherapy.&amp;aulast=Karver&amp;pid=%3Cauthor%3EKarver+MS%3C%2Fauthor%3E%3CAN%3E30335449%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 55
ER  -
TY  - JOUR
AB  - **Objectives: **
The aim of this review is to evaluate the effectiveness of shared/collaborative care between mental health-care providers and primary care providers (PCPs) on the outcomes of children and adolescents with attention-deficit/hyperactivity disorder (ADHD). This evaluation will be very helpful in the allocation of ADHD resources for models with the strongest evidence.

**Methods: **
Using the Preferred Reporting Items for Systematic Review and Meta-analysis statement, we searched for randomized controlled trials, cohort, case-control, and cross-sectional studies on shared/collaborative care models in the treatment of ADHD. Using MEDLINE, PsycINFO, and CENTRAL databases from January 2000 to December 2016, we retrieved English language articles for review. The validation search identified 75 records. Five studies met the inclusion criteria and were analyzed in this systematic review. There were insufficient data for a meta-analysis. The included studies involved 655 children and adolescents who had a diagnosis of ADHD. The Cochrane Collaboration&#039;s tool for assessing risk of bias was used to estimate bias.

**Results: **
Overall, the results show that the effects of shared/collaborative care models were small to moderate (effect size: 0.1-0.6, P = .04) on symptom rating scales, but all positively affected functional outcomes (effect size: 0.3-0.7, P = .04-.01). The data indicated that the models were associated with increased PCPs&#039; comfort levels, but the evidence for increased capacity for diagnosing and managing ADHD was weaker.

**Conclusions: **
This review concludes that the current studies do not show strong evidence for the outcome of collaboration between PCPs and mental health professionals on ADHD management. Future research should consider providing education to PCPs on management guidelines prior to conducting the trials, and more innovation is needed to discover methods of collaboration that affect the direct care of ADHD.
AD  - Sultan, Meshal A. Mental Health Center of Excellence, Al Jalila Children&#039;s Specialty Hospital, Dubai, United Arab Emirates.Pastrana, Carlos S. Neuroscience and Mental Health, Carleton University, Ottawa, Ontario, Canada.Pajer, Kathleen A. University of Ottawa Faculty of Medicine, Ottawa, Ontario, Canada.Pajer, Kathleen A. Children&#039;s Hospital of Eastern Ontario (CHEO), Ottawa, Ontario, Canada.
AN  - 29623286
AU  - Sultan,
AU  - M.
AU  - A.
AU  - Pastrana,
AU  - C.
AU  - S.
AU  - Pajer,
AU  - K.
AU  - A.
DA  - Jan-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/2333392818762886
DP  - Ovid Technologies
J2  - Health serv
L1  - internal-pdf://3653706413/Sultan-2018-Shared Care Models in the Treatmen.pdf
LA  - English
M3  - Review
N1  - Sultan, Meshal APastrana, Carlos SPajer, Kathleen A
PY  - 2018
SP  - 2333392818762886
T2  - Health Services Research &amp; Managerial Epidemiology
TI  - Shared Care Models in the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder (ADHD): Are They Effective?
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29623286
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29623286&amp;id=doi:10.1177%2F2333392818762886&amp;issn=2333-3928&amp;isbn=&amp;volume=5&amp;issue=&amp;spage=2333392818762886&amp;pages=2333392818762886&amp;date=2018&amp;title=Health+Services+Research+%26+Managerial+Epidemiology&amp;atitle=Shared+Care+Models+in+the+Treatment+of+Pediatric+Attention-Deficit%2FHyperactivity+Disorder+%28ADHD%29%3A+Are+They+Effective%3F.&amp;aulast=Sultan&amp;pid=%3Cauthor%3ESultan+MA%3C%2Fauthor%3E%3CAN%3E29623286%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 5
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
To perform a systematic review and meta-analysis on the effects of audiovisual distraction on reducing dental anxiety in children during dental treatment under local anesthesia. 

**METHODS: **
The authors identified eligible reports published through August 2017 by searching PubMed, EMBASE, and Cochrane Central Register of Controlled Trials. Clinical trials that reported the effects of audiovisual distraction on children&#039;s physiological measures, self-reports and behavior rating scales during dental treatment met the minimum inclusion requirements. The authors extracted data and performed a meta-analysis of appropriate articles. 

**RESULTS: **
Nine eligible trials were included and qualitatively analyzed; some of these trials were also quantitatively analyzed. Among the physiological measures, heart rate or pulse rate was significantly lower (p=0.01) in children subjected to audiovisual distraction during dental treatment under local anesthesia than in those who were not; a significant difference in oxygen saturation was not observed. The majority of the studies using self-reports and behavior rating scales suggested that audiovisual distraction was beneficial in reducing anxiety perception and improving children&#039;s cooperation during dental treatment. 

**CONCLUSION: **
The audiovisual distraction approach effectively reduces dental anxiety among children. Therefore, we suggest the use of audiovisual distraction when children need dental treatment under local anesthesia. This article is protected by copyright. All rights reserved.
AN  - 29498793
AU  - Zhang,
AU  - C.
AU  - Qin,
AU  - D.
AU  - Shen,
AU  - L.
AU  - Ji,
AU  - P.
AU  - Wang,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/odi.12849
L1  - internal-pdf://2413949273/Zhang-2018-Does audiovisual distraction reduce.pdf
PY  - 2018
SP  - 02
T2  - Oral Diseases
TI  - Does audiovisual distraction reduce dental anxiety in children under local anesthesia? A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29498793
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1111/odi.12849
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/odi.12849
VL  - 02
ER  -
TY  - JOUR
AB  - BAKGRUNN
Artikkelen er en revidert kunnskapsoppsummering om effekten av den skoleomfattende modellen &laquo;Positiv atferd, støttende læringsmiljø og samhandling&raquo; (PALS) (Natvig &amp; Eng, 2012), nå oppdatert i henhold til Ungsinns nye prosedyrer og kriterier. PALS er en skoleomfattende tiltaksmodell med mål om å utvikle en positiv skolekultur for å styrke elevenes skolefaglige og sosiale ferdigheter, samt å forebygge og redusere problematferd. Alle elever og ansatte i 1.-10. klasse er i målgruppen for modellen der alle involveres i og utenom undervisningssituasjonen på alle skolens områder. PALS er en norsk tilpasning av School-Wide Positive Behavioral Intervention and Support (SW-PBIS) som bl.a. er utviklet ved Universitetet i Oregon. Modellen er videreutviklet og tilpasset norske forhold av Nasjonalt utviklingssenter for barn og unge (NUBU) som også er ansvarlig for
administrering av opplæring og implementering av modellen i Norge.

METODE
Kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Blueprints, Cambell, CEBC, CRIStin, Cochrane, Embase, Medline, NORA, Norart, NICE, NREPP, PsycINFO, Scopus og SweMed. I tillegg er søk i internasjonale kunnskapsdatabaser om evidens utført og informasjon fra tiltakseier innhentet. Ni artikler, derav fire norske effektartikler med utgangspunkt i to effektstudier, to internasjonale kunnskapsoppsummeringer og tre andre norske evalueringer ble inkludert med i denne kunnskapsoppsummeringen av PALS.

RESULTATER
Resultatene består av en vurdering av tiltaksmodellens beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. PALS-modellen er grundig teoretisk forankret og er godt beskrevet i detaljerte håndbøker, faglitteratur og i øvrig tilleggsmateriell knyttet til opplæring og implementering. Det foreligger to norske effektevalueringer. Første evaluering er en mindre studie utført som et kvasi-eksperimentelt kontrollgruppedesign med pre- og postmålinger. Positive effekter ble funnet i første studie, men studien har svak forskningsmetodiske kvalitet og det kan stilles spørsmål ved indre validitet og generaliserbarheten av funnene. Den andre evalueringen er en større effektstudie og omfatter flere artikler, hvor tre er inkludert i denne kunnskapsoppsummeringen. Denne studien har god forskningsmetodisk kvalitet og ble utført som et styrket kvasi-eksperimentelt design. I andre studie er både PALS fullversjon implementert over tre år og PALS komprimert versjon implementert over ett år evaluert. Her ble positive effekter på flere relevante utfallsmål funnet og som vurderes til å være av praktisk betydning. Flere effektartikler er under utarbeidelse, herunder om utfallsmål på endring i problematferd for elever i ulik risiko og på endring i sosiale ferdigheter. Modellen har gode systemer for å sikre god implementeringskvalitet, noe som gjør det sannsynlig å implementere modellen som forutsatt i praksis. 

KONKLUSJON
Både de norske og internasjonale studiene finner at PALS fører til reduksjon i forekomsten av generell og moderat problematferd og i noe grad alvorlig problematferd i skolemiljøet. De norske studiene fant også at ansatte i skolen i større grad tok i bruk positivt støttende reaksjonsmåter etter implementeringen PALS. I tillegg viste moderatoranalyser at høy implementeringskvalitet var assosiert med større intervensjonseffekter i de norske studiene. Dersom senere artikler rapporterer om at tiltaket også fører til positive endringer i elevenes sosiale ferdigheter, vil dette styrke evidensen til tiltaket ytterligere. Modellen imøtekommer kravene for sterk dokumentasjon på effekt for flere av målsetningene ved tiltaket og tiltaket klassifiseres på evidensnivå 5 &ndash; tiltak med sterk dokumentasjon på effekt.
AU  - Aasheim,
AU  - M.,
AU  - Patras,
AU  - J.,
AU  - Eng,
AU  - H.,
AU  - Natvig,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
KW  - Psychology: 260
KW  - Psykologi: 260
KW  - Samfunnsvitenskap: 200
KW  - Social science: 200
KW  - VDP
N1  - BAKGRUNN: Artikkelen er en revidert kunnskapsoppsummering om effekten av den skoleomfattende modellen &laquo;Positiv atferd, støttende læringsmiljø og samhandling&raquo; (PALS) (Natvig &amp; Eng, 2012), nå oppdatert i henhold til Ungsinns nye prosedyrer og kriterier. PALS er en skoleomfattende tiltaksmodell med mål om å utvikle en positiv skolekultur for å styrke elevenes skolefaglige og sosiale ferdigheter, samt å forebygge og redusere problematferd. Alle elever og ansatte i 1.-10. klasse er i målgruppen for modellen der alle involveres i og utenom undervisningssituasjonen på alle skolens områder. PALS er en norsk tilpasning av School-Wide Positive Behavioral Intervention and Support (SW-PBIS) som bl.a. er utviklet ved Universitetet i Oregon. Modellen er videreutviklet og tilpasset norske forhold av Nasjonalt utviklingssenter for barn og unge (NUBU) som også er ansvarlig for administrering av opplæring og implementering av modellen i Norge. METODE: Kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Blueprints, Cambell, CEBC, CRIStin, Cochrane, Embase, Medline, NORA, Norart, NICE, NREPP, PsycINFO, Scopus og SweMed. I tillegg er søk i internasjonale kunnskapsdatabaser om evidens utført og informasjon fra tiltakseier innhentet. Ni artikler, derav fire norske effektartikler med utgangspunkt i to effektstudier, to internasjonale kunnskaps-oppsummeringer og tre andre norske evalueringer ble inkludert med i denne kunnskapsoppsummeringen av PALS. RESULTATER: Resultatene består av en vurdering av tiltaksmodellens beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. PALS-modellen er grundig teoretisk forankret og er godt beskrevet i detaljerte håndbøker, faglitteratur og i øvrig tilleggsmateriell knyttet til opplæring og implementering. Det foreligger to norske effekt-evalueringer. Første evaluering er en mindre studie utført som et kvasi-eksperimentelt kontrollgruppedesign med pre- og postmålinger. Positive effekter ble funnet i første studie, men studien har svak forskningsmetodiske kvalitet og det kan stilles spørsmål ved indre validitet og generaliserbarheten av funnene. Den andre evalueringen er en større effektstudie og omfatter flere artikler, hvor tre er inkludert i denne kunnskapsoppsummeringen. Denne studien har god forskningsmetodisk kvalitet og ble utført som et styrket kvasi-eksperimentelt design. I andre studie er både PALS fullversjon implementert over tre år og PALS komprimert versjon implementert over ett år evaluert. Her ble positive effekter på flere relevante utfallsmål funnet og som vurderes til å være av praktisk betydning. Flere effektartikler er under utarbeidelse, herunder om utfallsmål på endring i problematferd for elever i ulik risiko og på endring i sosiale ferdigheter. Modellen har gode systemer for å sikre god implementeringskvalitet, noe som gjør det sannsynlig å implementere modellen som forutsatt i praksis. KONKLUSJON: Både de norske og internasjonale studiene finner at PALS fører til reduksjon i forekomsten av generell og moderat problematferd og i noe grad alvorlig problematferd i skolemiljøet. De norske studiene fant også at ansatte i skolen i større grad tok i bruk positivt støttende reaksjonsmåter etter implementeringen PALS. I tillegg viste moderatoranalyser at høy implementeringskvalitet var assosiert med større intervensjonseffekter i de norske studiene. Dersom senere artikler rapporterer om at tiltaket også fører til positive endringer i elevenes sosiale ferdigheter, vil dette styrke evidensen til tiltaket ytterligere. Modellen imøtekommer kravene for sterk dokumentasjon på effekt for flere av målsetningene ved tiltaket og tiltaket klassifiseres på evidensnivå 5 &ndash; tiltak med sterk dokumentasjon på effekt.Ungsinn. Tidsskrift for virksomme tiltak for barn og unge
PY  - 2018
T2  - Ungsinn
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: PALS &ndash; Positiv atferd, støttende læringsmiljø og samhandling (2.utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/pals-positiv-atferd-stottende-laeringsmiljo-2-utg/
ER  -
TY  - JOUR
AB  - This paper presents the results from a systematic and meta-analytical review of the effectiveness of cyberbullying intervention and prevention programs. Systematic searches were conducted for published and unpublished studies from 2000 to end 2017 on several online databases, including Web of Science, Scopus, PsychINFO, PsychARTICLES, Google Scholar, DARE, and ERIC. In addition, specific journals, for example, Cyberpsychology, Behavior, and Social Networking and Computers in Human Behavior, were hand searched for relevant studies. 

In total, 192 studies were retained for further screening from nearly 4000 search results. To be included in the present systematic review, studies had to: (1) include an adequate operational definition of cyberbullying; (2) describe the evaluation of an intervention or prevention program implemented with school-aged participants; (3) Employ experimental and control conditions; (4) Measure cyber-bullying behaviors using quantitative measurement instruments; and (5) have been published from 2000 onwards. Following rigorous screening, 24 publications were included in our systematic review. The majority of these studies (n = 15) used randomized controlled trials (RCTs) to evaluate anti-cyberbullying programs, while the remaining studies used quasi-experimental designs with before and after measures (n = 9). 

Within these 24 publications, 26 independent evaluations were reported. We conducted a meta-analysis to synthesize the results of primary evaluations of cyberbullying intervention programs. Our meta-analysis included 18 and 19 independent effect sizes for cyberbullying perpetration and cyberbullying victimization independently. The results of our meta-analysis suggest that cyberbullying intervention programs are effective in reducing both cyberbullying perpetration and victimization. 

Our results indicate that anti-cyberbullying programs can reduce cyberbullying perpetration by approximately 10%-15% and cyberbullying victimization by approximately 14%. We also compared results between different methodological designs and models of meta-analysis. The effect sizes were greater for RCTs than for quasi-experimental designs. Overall, the results of the present report address a significant gap in the cyberbullying literature, and suggest that intervention and prevention can be effective. 

However, future research needs to address the specific components of interventions that are effective, the effectiveness of prevention programs with non-school-aged samples, and the influence of overlapping offline and online victimization. 
Copyright &copy; 2018 Elsevier Ltd
AD  - (Gaffney, Farrington, Ttofi) Institute of Criminology, University of Cambridge, United Kingdom (Espelage) University of Florida, United StatesH. Gaffney, Institute of Criminology, Sidgwick Avenue, Cambridge CB3 9DA, United Kingdom. E-mail: hg409@cam.ac.uk
AN  - 2000977899
AU  - Gaffney,
AU  - H.
AU  - Farrington,
AU  - D.
AU  - P.
AU  - Espelage,
AU  - D.
AU  - L.
AU  - Ttofi,
AU  - M.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.avb.2018.07.002
DP  - Ovid Technologies
KW  - Anti-bullying
KW  - Bullying
KW  - Cyberbullying
KW  - Effectiveness
KW  - Intervention and prevention
KW  - Meta-analysis
KW  - Online bullying
KW  - adult
KW  - article
KW  - computer
KW  - effect size
KW  - experimental design
KW  - female
KW  - human
KW  - human experiment
KW  - male
KW  - meta analysis
KW  - PsycINFO
KW  - publication
KW  - quantitative analysis
KW  - randomized controlled trial (topic)
KW  - Scopus
KW  - social network
KW  - systematic review
KW  - Web of Science
L1  - internal-pdf://1701054651/Gaffney-2018-Are cyberbullying intervention an.pdf
LA  - English
M3  - In Press
N1  - Using Smart Source ParsingDate of Publication: 2018
PY  - 2018
T2  - Aggression and Violent Behavior.
TI  - Are cyberbullying intervention and prevention programs effective? A systematic and meta-analytical review
UR  - http://www.elsevier.com/locate/aggviobeh
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2000977899
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.avb.2018.07.002&amp;issn=1359-1789&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Aggression+and+Violent+Behavior&amp;atitle=Are+cyberbullying+intervention+and+prevention+programs+effective%3F+A+systematic+and+meta-analytical+review&amp;aulast=Gaffney&amp;pid=%3Cauthor%3EGaffney+H.%3C%2Fauthor%3E%3CAN%3E2000977899%3C%2FAN%3E%3CDT%3EArticle+In+Press%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S1359178918300697/1-s2.0-S1359178918300697-main.pdf?_tid=1333d77a-aa70-4fc8-87fc-a498e28f7652&amp;acdnat=1539256930_9cc994258def5cd74a32cefe6c26ddbd
ER  -
TY  - JOUR
AB  - Neurofeedback (NF) has gained increasing interest in the treatment of attention-deficit/hyperactivity disorder (ADHD). Given learning principles underlie NF, lasting clinical treatment effects may be expected. This systematic review and meta-analysis addresses the sustainability of neurofeedback and control treatment effects by considering randomized controlled studies that conducted follow-up (FU; 2-12 months) assessments among children with ADHD. PubMed and Scopus databases were searched through November 2017. 

Within-group and between-group standardized mean differences (SMD) of parent behavior ratings were calculated and analyzed. Ten studies met inclusion criteria (NF: ten studies, N = 256; control: nine studies, N = 250). Within-group NF effects on inattention were of medium effect size (ES) (SMD = 0.64) at post-treatment and increased to a large ES (SMD = 0.80) at FU. 

Regarding hyperactivity/impulsivity, NF ES were medium at post-treatment (SMD = 0.50) and FU (SMD = 0.61). Non-active control conditions yielded a small significant ES on inattention at post-treatment (SMD = 0.28) but no significant ES at FU. Active treatments (mainly methylphenidate), had large ES for inattention (post: SMD = 1.08; FU: SMD = 1.06) and medium ES for hyperactivity/impulsivity (post: SMD = 0.74; FU: SMD = 0.67). 

Between-group analyses also revealed an advantage of NF over non-active controls [inattention (post: SMD = 0.38; FU: SMD = 0.57); hyperactivity-impulsivity (post: SMD = 0.25; FU: SMD = 0.39)], and favored active controls for inattention only at pre-post (SMD = - 0.44). Compared to non-active control treatments, NF appears to have more durable treatment effects, for at least 6 months following treatment. 

More studies are needed for a properly powered comparison of follow-up effects between NF and active treatments and to further control for non-specific effects. 

Copyright &copy; 2018 The Author(s)
AN  - 620718862
AU  - van
AU  - Doren,
AU  - J.
AU  - Arns,
AU  - M.
AU  - Heinrich,
AU  - H.
AU  - Vollebregt,
AU  - M.
AU  - A.
AU  - Strehl,
AU  - U.
AU  - Loo,
AU  - S.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00787-018-1121-4
L1  - internal-pdf://0996599467/van Doren-2018-Sustained effects of neurofeedb.pdf
PY  - 2018
SP  - 1-13
T2  - European Child and Adolescent Psychiatry
TI  - Sustained effects of neurofeedback in ADHD: a systematic review and meta-analysis
UR  - http://www.springerlink.com/content/1018-8827
UR  - https://link.springer.com/content/pdf/10.1007%2Fs00787-018-1121-4.pdf
ER  -
TY  - JOUR
AB  - Suicide is a leading cause of death in adolescence. School provides an effective avenue both for reaching adolescents and for gatekeeper training. This enables gatekeepers to recognize and respond to at-risk students and is a meaningful focus for the provision of suicide prevention. This study provides the first systematic review on the effectiveness of school-based gatekeeper training in enhancing gatekeeper-related outcomes. 

A total of 815 studies were identified through four databases (Ovid Medline, Embase, PsycINFO and ERIC) using three groups of keywords: &#039;school based&#039;, &#039;Suicide prevention programme&#039; and &#039;Gatekeeper&#039;. Fourteen of these studies were found to be adequate for inclusion in this systematic review. The improvement in gatekeepers&#039; knowledge; attitudes; self-efficacy; skills; and likelihood to intervene were found in most of the included studies. 

Evidence of achieving improvement in attitudes and gatekeeper behaviour was mixed. Most included studies were methodologically weak. Gatekeeper training appears to have the potential to change participants&#039; knowledge and skills in suicide prevention, but more studies of better quality are needed to determine its effectiveness in changing gatekeepers&#039; attitudes. There is also an urgent need to investigate how best improvements in knowledge and skills can be translated into behavioural change.
AD  - [Mo, Phoenix K. H.; Xin, Mei Qi] Chinese Univ Hong Kong, Fac Med, Sch Publ Hlth &amp; Primary Care, Div Behav Hlth &amp; Hlth Promot, Shatin, Hong Kong, Peoples R China. [Ko, Ting Ting] Chinese Univ Hong Kong, Fac Med, Sch Publ Hlth &amp; Primary Care, Shatin, Hong Kong, Peoples R China.Mo, PKH (reprint author), Chinese Univ Hong Kong, Fac Med, Sch Publ Hlth &amp; Primary Care, Div Behav Hlth &amp; Hlth Promot, Shatin, Hong Kong, Peoples R China.phoenix.mo@cuhk.edu.hk
AN  - WOS:000434660300001
AU  - Mo,
AU  - P.
AU  - K.
AU  - H.
AU  - Ko,
AU  - T.
AU  - T.
AU  - Xin,
AU  - M.
AU  - Q.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/s13034-018-0233-4
J2  - Child Adolesc. Psychiatry Ment. Health
KW  - Adolescents
KW  - Gatekeeper training
KW  - School-based
KW  - Suicide prevention
KW  - Systematic review
KW  - youth suicide
KW  - mental-health
KW  - self-injury
KW  - knowledge
KW  - staff
KW  - attitudes
KW  - risk
KW  - intervention
KW  - outcomes
KW  - college
KW  - Pediatrics
KW  - Psychiatry
L1  - internal-pdf://3446085614/Mo-2018-School-based gatekeeper training progr.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GI7CQTimes Cited: 0Cited Reference Count: 62Mo, Phoenix K. H. Ko, Ting Ting Xin, Mei Qi02Biomed central ltdLondon
PY  - 2018
SP  - 29
T2  - Child and Adolescent Psychiatry and Mental Health
TI  - School-based gatekeeper training programmes in enhancing gatekeepers&#039; cognitions and behaviours for adolescent suicide prevention: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000434660300001
UR  - https://capmh.biomedcentral.com/track/pdf/10.1186/s13034-018-0233-4
VL  - 12
ER  -
TY  - JOUR
AB  - A comprehensive and extensive systematic review and meta-analysis of the effectiveness of bullying prevention programs is presented. This report updates earlier research conducted by Farrington and Ttofi (2009). Systematic searches of online databases (i.e., Web of Science, PsychARTICLES, PsychINFO, EMBASE, DARE, ERIC, Google scholar, and Scopus) were conducted for primary studies published from 2009 to December 2016. Searches were also conducted for unpublished reports. 

To be included in the systematic review, primary studies must: (1) describe an evaluation of a school-based anti-bullying program; (2) utilize an appropriate operational definition of school-bullying (e.g., Centers for Disease Control and Prevention, 2014; Farrington, 1993; Olweus, 1992); (3) measure school-bullying perpetration and/or victimization behaviors using quantitative measures; and (4) use an experimental or quasi-experimental design with adequate control group. Following systematic screening of over 20,000 search results, a total of 100 evaluations (with 103 independent effect sizes) were eligible for inclusion in our meta-analysis. Most of the effect sizes are estimated from studies that used RCT designs (n = 45) or quasi-experiments (n = 44 effect sizes), with only 14 effect sizes from age cohort designs.

Anti-bullying programs significantly reduce bullying perpetration (random effects OR = 1.309) and bullying victimization (random effects OR = 1.244). These results suggest that anti-bullying programs reduce school-bullying perpetration by approximately 19-20% ad school-bullying victimization by approximately 15-16%. Effect sizes vary greatly across studies, with a significant heterogeneity between studies for both bullying perpetration bullying victimization outcomes. This is anticipated given the variability in a range of moderators, for example, methodological designs, type of program used, or place of implementation. Analyses suggest no publication bias for either meta-analysis. Variability in effect sizes across different methodological designs is investigated. 

Primary studies employing age cohort designs (n = 14) provide the largest effects in reducing both bullying perpetration (OR = 1.474) and victimization (OR = 1.302). In relation to bullying victimization outcomes, before-after/experimental-control designs provide similar effects (OR = 1.225) to randomized controlled trials (OR = 1.21). Randomized controlled trials (OR = 1.244) are more effective in reducing bullying perpetration than before-after/experimental-control designs (OR = 1.187). In future, we aim to further explain differences across programs by correlating individual effect sizes with varying program components and varying methodological elements available across these 100 evaluations. 

Copyright &copy; 2018 Elsevier Ltd
AD  - (Gaffney, Ttofi, Farrington) Institute of Criminology, University of Cambridge, United KingdomH. Gaffney, Institute of Criminology, Sidgwick Avenue, Cambridge CB3 9DA, United Kingdom. E-mail: hg409@cam.ac.uk
AN  - 2001032036
AU  - Gaffney,
AU  - H.
AU  - Ttofi,
AU  - M.
AU  - M.
AU  - Farrington,
AU  - D.
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.avb.2018.07.001
DP  - Ovid Technologies
KW  - Anti-bullying programs
KW  - Bullying perpetration and victimization
KW  - Evaluation
KW  - Intervention
KW  - Meta-analysis
KW  - Prevention
KW  - School bullying
KW  - Traditional bullying
KW  - article
KW  - bullying
KW  - cohort analysis
KW  - comparative effectiveness
KW  - controlled study
KW  - disease control
KW  - effect size
KW  - Embase
KW  - experimental design
KW  - human
KW  - meta analysis
KW  - PsycINFO
KW  - publishing
KW  - quantitative analysis
KW  - randomized controlled trial (topic)
KW  - Scopus
KW  - systematic review
KW  - Web of Science
L1  - internal-pdf://1180305751/Gaffney-2018-Evaluating the effectiveness of s.pdf
LA  - English
M3  - In Press
N1  - Using Smart Source ParsingDate of Publication: 2018
PY  - 2018
T2  - Aggression and Violent Behavior.
TI  - Evaluating the effectiveness of school-bullying prevention programs: An updated meta-analytical review
UR  - http://www.elsevier.com/locate/aggviobeh
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2001032036
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.avb.2018.07.001&amp;issn=1359-1789&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Aggression+and+Violent+Behavior&amp;atitle=Evaluating+the+effectiveness+of+school-bullying+prevention+programs%3A+An+updated+meta-analytical+review&amp;aulast=Gaffney&amp;pid=%3Cauthor%3EGaffney+H.%3C%2Fauthor%3E%3CAN%3E2001032036%3C%2FAN%3E%3CDT%3EArticle+In+Press%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S1359178918300727/1-s2.0-S1359178918300727-main.pdf?_tid=9548a873-5bac-4c87-a401-f629f2884802&amp;acdnat=1539256933_af44d8a6af0af1eedc89b2464ee5aac3
ER  -
TY  - JOUR
AB  - This multilevel meta-analysis examined the effects of treatment for juveniles with harmful sexual behavior on psychosocial functioning, and the potential moderating effects of outcome, treatment, participant, and study characteristics. In total, 23 studies, comprising 31 independent samples and 1342 participants, yielded 362 effect sizes (Cohen&#039;s d). 

A moderate overall effect size was found of d = 0.60, indicating that groups receiving treatment achieved an estimated relative improvement in psychosocial functioning of 33%. Type of outcome did moderate the effect of treatment, indicating that effects on atypical sexual arousal and empathy (a trend) were smaller, compared to effects on other outcomes. 

Most prominently, studies of weak quality produced larger effect sizes. Unexpectedly, non-established treatments had more effect than did established treatments, which may be explained by the use of less rigorous study designs. 

Treatment groups with a higher percentage of juveniles with similar age victims or mixed type problem behavior also yielded larger effect sizes. Lastly, evaluation of treatment effects by professionals produced higher effect sizes, compared to other sources of information (e.g., adolescent self-report). 

Although only a marginal to no indication was found for publication bias by means of funnel plot analysis of the distribution of effect sizes, articles published in peer reviewed journals showed relatively large effect sizes. Implications for future research and clinical practice are discussed. 

Copyright &copy; 2018 Elsevier Ltd
AN  - 620753886
AU  - ter
AU  - Beek,
AU  - E.
AU  - Kuiper,
AU  - C.
AU  - H.
AU  - Z.
AU  - van
AU  - der
AU  - Rijken,
AU  - R.
AU  - E.
AU  - A.
AU  - Spruit,
AU  - A.
AU  - Stams,
AU  - G.
AU  - J.
AU  - J.
AU  - M.
AU  - Hendriks,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.avb.2018.02.008
L1  - internal-pdf://2105277260/ter Beek_2018.pdf
PY  - 2018
SP  - 116-128
T2  - Aggression and Violent Behavior
TI  - Treatment effect on psychosocial functioning of juveniles with harmful sexual behavior: A multilevel meta-analysis
UR  - http://www.elsevier.com/locate/aggviobeh
UR  - https://www.sciencedirect.com/science/article/pii/S1359178917303397?via%3Dihub
VL  - 39
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To conduct a systematic review and meta-analyses to assess the effect of manual therapy interventions for healthy but unsettled, distressed and excessively crying infants and to provide information to help clinicians and parents inform decisions about care.

**METHODS: **
We reviewed published peer-reviewed primary research articles in the last 26 years from nine databases (Medline Ovid, Embase, Web of Science, Physiotherapy Evidence Database, Osteopathic Medicine Digital Repository , Cochrane (all databases), Index of Chiropractic Literature, Open Access Theses and Dissertations and Cumulative Index to Nursing and Allied Health Literature). Our inclusion criteria were: manual therapy (by regulated or registered professionals) of unsettled, distressed and excessively crying infants who were otherwise healthy and treated in a primary care setting. Outcomes of interest were: crying, feeding, sleep, parent-child relations, parent experience/satisfaction and parent-reported global change.

**RESULTS: **
Nineteen studies were selected for full review: seven randomised controlled trials, seven case series, three cohort studies, one service evaluation study and one qualitative study.We found moderate strength evidence for the effectiveness of manual therapy on: reduction in crying time (favourable: -1.27 hours per day (95% CI -2.19 to -0.36)), sleep (inconclusive), parent-child relations (inconclusive) and global improvement (no effect). The risk of reported adverse events was low: seven non-serious events per 1000 infants exposed to manual therapy (n=1308) and 110 per 1000 in those not exposed.

**CONCLUSIONS: **
Some small benefits were found, but whether these are meaningful to parents remains unclear as does the mechanisms of action. Manual therapy appears relatively safe.

Prospero registration number: Crd42016037353.
AD  - Carnes, Dawn. Barts and The London School of Medicine and Dentistry, Centre for Primary Care and Public Health, Queen Mary University of London, London, UK.Carnes, Dawn. Faculty of Health, Universtiy of Applied Sciences, Western Switzerland, Fribourg, Switzerland.Carnes, Dawn. National Council for Osteopathic Research, London, UK.Plunkett, Austin. Barts and The London School of Medicine and Dentistry, Centre for Primary Care and Public Health, Queen Mary University of London, London, UK.Plunkett, Austin. National Council for Osteopathic Research, London, UK.Ellwood, Julie. National Council for Osteopathic Research, London, UK.Miles, Clare. Barts and The London School of Medicine and Dentistry, Centre for Primary Care and Public Health, Queen Mary University of London, London, UK.
AN  - 29371279
AU  - Carnes,
AU  - D.
AU  - Plunkett,
AU  - A.
AU  - Ellwood,
AU  - J.
AU  - Miles,
AU  - C.
DA  - 01 24
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmjopen-2017-019040
DP  - Ovid Technologies
J2  - BMJ Open
KW  - *Crying/px [Psychology]
KW  - Emotions
KW  - Humans
KW  - Infant
KW  - *Infant Behavior
KW  - *Infant Care/mt [Methods]
KW  - *Musculoskeletal Manipulations/mt [Methods]
KW  - Parent-Child Relations
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://2513698739/Carnes-2018-Manual therapy for unsettled, dist.pdf
LA  - English
M3  - Meta-Analysis
Research Support, Non-U.S. Gov&#039;t
Review
N1  - Carnes, DawnPlunkett, AustinEllwood, JulieMiles, Clare
PY  - 2018
SP  - e019040
T2  - BMJ Open
TI  - Manual therapy for unsettled, distressed and excessively crying infants: a systematic review and meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=29371279
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29371279&amp;id=doi:10.1136%2Fbmjopen-2017-019040&amp;issn=2044-6055&amp;isbn=&amp;volume=8&amp;issue=1&amp;spage=e019040&amp;pages=e019040&amp;date=2018&amp;title=BMJ+Open&amp;atitle=Manual+therapy+for+unsettled%2C+distressed+and+excessively+crying+infants%3A+a+systematic+review+and+meta-analyses.&amp;aulast=Carnes&amp;pid=%3Cauthor%3ECarnes+D%3C%2Fauthor%3E%3CAN%3E29371279%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988120/pdf/bmjopen-2017-019040.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
Higher intakes of foods containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA), such as fish, during pregnancy have been associated with longer gestations and improved perinatal outcomes. This is an update of a review that was first published in 2006.

**OBJECTIVES:**
To assess the effects of omega-3 LCPUFA, as supplements or as dietary additions, during pregnancy on maternal, perinatal, and neonatal outcomes and longer-term outcomes for mother and child.

**SEARCH METHODS:**
For this update, we searched Cochrane Pregnancy and Childbirth&#039;s Trials Register, ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform (ICTRP) (16 August 2018), and reference lists of retrieved studies.

**SELECTION CRITERIA:**
Randomised controlled trials (RCTs) comparing omega-3 fatty acids (as supplements or as foods, stand-alone interventions, or with a co-intervention) during pregnancy with placebo or no omega-3, and studies or study arms directly comparing omega-3 LCPUFA doses or types. Trials published in abstract form were eligible for inclusion.

**DATA COLLECTION AND ANALYSIS:**
Two review authors independently assessed study eligibility, extracted data, assessed risk of bias in trials and assessed quality of evidence for prespecified birth/infant, maternal, child/adult and health service outcomes using the GRADE approach.

**MAIN RESULTS:**
In this update, we included 70 RCTs (involving 19,927 women at low, mixed or high risk of poor pregnancy outcomes) which compared omega-3 LCPUFA interventions (supplements and food) compared with placebo or no omega-3. Overall study-level risk of bias was mixed, with selection and performance bias mostly at low risk, but there was high risk of attrition bias in some trials. Most trials were conducted in upper-middle or high-income countries; and nearly half the trials included women at increased/high risk for factors which might increase the risk of adverse maternal and birth outcomes.Preterm birth &lt; 37 weeks (13.4% versus 11.9%; risk ratio (RR) 0.89, 95% confidence interval (CI) 0.81 to 0.97; 26 RCTs, 10,304 participants; high-quality evidence) and early preterm birth &lt; 34 weeks (4.6% versus 2.7%; RR 0.58, 95% CI 0.44 to 0.77; 9 RCTs, 5204 participants; high-quality evidence) were both lower in women who received omega-3 LCPUFA compared with no omega-3. Prolonged gestation &gt; 42 weeks was probably increased from 1.6% to 2.6% in women who received omega-3 LCPUFA compared with no omega-3 (RR 1.61 95% CI 1.11 to 2.33; 5141 participants; 6 RCTs; moderate-quality evidence).For infants, there was a possibly reduced risk of perinatal death (RR 0.75, 95% CI 0.54 to 1.03; 10 RCTs, 7416 participants; moderate-quality evidence: 62/3715 versus 83/3701 infants) and possibly fewer neonatal care admissions (RR 0.92, 95% CI 0.83 to 1.03; 9 RCTs, 6920 participants; moderate-quality evidence - 483/3475 infants versus 519/3445 infants). There was a reduced risk of low birthweight (LBW) babies (15.6% versus 14%; RR 0.90, 95% CI 0.82 to 0.99; 15 trials, 8449 participants; high-quality evidence); but a possible small increase in large-for-gestational age (LGA) babies (RR 1.15, 95% CI 0.97 to 1.36; 6 RCTs, 3722 participants; moderate-quality evidence, for omega-3 LCPUFA compared with no omega-3. Little or no difference in small-for-gestational age or intrauterine growth restriction (RR 1.01, 95% CI 0.90 to 1.13; 8 RCTs, 6907 participants; moderate-quality evidence) was seen.For the maternal outcomes, there is insufficient evidence to determine the effects of omega-3 on induction post-term (average RR 0.82, 95% CI 0.22 to 2.98; 3 trials, 2900 participants; low-quality evidence), maternal serious adverse events (RR 1.04, 95% CI 0.40 to 2.72; 2 trials, 2690 participants; low-quality evidence), maternal admission to intensive care (RR 0.56, 95% CI 0.12 to 2.63; 2 trials, 2458 participants; low-quality evidence), or postnatal depression (average RR 0.99, 95% CI 0.56 to 1.77; 2 trials, 2431 participants; low-quality evidence). Mean gestational length was greater in women who received omega-3 LCPUFA (mean difference (MD) 1.67 days, 95% CI 0.95 to 2.39; 41 trials, 12,517 participants; moderate-quality evidence), and pre-eclampsia may possibly be reduced with omega-3 LCPUFA (RR 0.84, 95% CI 0.69 to 1.01; 20 trials, 8306 participants; low-quality evidence).For the child/adult outcomes, very few differences between antenatal omega-3 LCPUFA supplementation and no omega-3 were observed in cognition, IQ, vision, other neurodevelopment and growth outcomes, language and behaviour (mostly low-quality to very low-quality evidence). The effect of omega-3 LCPUFA on body mass index at 19 years (MD 0, 95% CI -0.83 to 0.83; 1 trial, 243 participants; very low-quality evidence) was uncertain. No data were reported for development of diabetes in the children of study participants.

**AUTHORS&#039; CONCLUSIONS:**
In the overall analysis, preterm birth &lt; 37 weeks and early preterm birth &lt; 34 weeks were reduced in women receiving omega-3 LCPUFA compared with no omega-3. There was a possibly reduced risk of perinatal death and of neonatal care admission, a reduced risk of LBW babies; and possibly a small increased risk of LGA babies with omega-3 LCPUFA.For our GRADE quality assessments, we assessed most of the important perinatal outcomes as high-quality (e.g. preterm birth) or moderate-quality evidence (e.g. perinatal death). For the other outcome domains (maternal, child/adult and health service outcomes) GRADE ratings ranged from moderate to very low, with over half rated as low. Reasons for downgrading across the domain were mostly due to design limitations and imprecision.Omega-3 LCPUFA supplementation during pregnancy is an effective strategy for reducing the incidence of preterm birth, although it probably increases the incidence of post-term pregnancies. More studies comparing omega-3 LCPUFA and placebo (to establish causality in relation to preterm birth) are not needed at this stage. A further 23 ongoing trials are still to report on over 5000 women, so no more RCTs are needed that compare omega-3 LCPUFA against placebo or no intervention. However, further follow-up of completed trials is needed to assess longer-term outcomes for mother and child, to improve understanding of metabolic, growth and neurodevelopment pathways in particular, and to establish if, and how, outcomes vary by different types of omega-3 LCPUFA, timing and doses; or by characteristics of women.
AU  - Middleton,
AU  - P.
AU  - Gomersall,
AU  - J.
AU  - C.
AU  - Gould,
AU  - J.
AU  - F.
AU  - Shepherd,
AU  - E.
AU  - Olsen,
AU  - S.
AU  - F.
AU  - Makrides,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD003402.pub3.
L1  - internal-pdf://1463719007/Middleton-2018-Omega‐3 fatty acid addition dur.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Omega‐3 fatty acid addition during pregnancy
ER  -
TY  - JOUR
AB  - **Objective **
The aim of this study is to perform the first meta-meta-analysis on the effectiveness of parent-based interventions for children with externalizing behavior problems. Even though parent-based interventions are considered as effective treatments the effects reported in meta-analyses are heterogeneous and the implementation in clinical practice is suboptimal. Recapitulative valid effect predictions are required to close the still existing gap between research findings and clinical practice. The meta-meta-analytic results on changes in child behavior shall result in a clear signal for clinical practice. 

**Methods **
This meta-meta-analysis encompasses 26 meta-analyses identified via search in electronic databases (PsycINFO, Medline, PubMed). Meta-analyses had to report effects of parent-based interventions on child behavior and focus on children under the age of 13 years with externalizing behavior problems in a clinical setting. Analyses were based on random-effects models. To combine results, the effect estimates of the meta-analyses were transformed to SMD and weighted to correct for primary study overlap. The meta-meta-analysis is registered on PROSPERO, registration number CRD42016036486 and was conducted in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses statement (PRISMA). 

**Results **
The results indicate a significant moderate overall effect for child behavior (SMD = 0.46) as well as for parent reports (SMD = 0.51) and observational data (SMD = 0.62). Further analyses focusing on child externalizing behavior yielded significant and moderate effects (SMD = 0.45). All effects remained stable to follow-up. Considerable heterogeneity was observed within results. 

**Conclusion**
Parent-based interventions are shown to be effective in improving behavior in children with externalizing behavior problems, as assessed using parent reports and observational measures. The present results should encourage health care providers to apply evidence-based parent-based interventions. 

Copyright &copy; 2018 Mingebach et al. 
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AD  - (Mingebach, Kamp-Becker, Weber) Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Marburg, Germany (Christiansen) Department of Clinical Child and Adolescent Psychology, Philipps University Marburg, Marburg, GermanyT. Mingebach, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Marburg, Germany. E-mail: tanja.mingebach@med.uni-marburg.de
AN  - 624020694
AU  - Mingebach,
AU  - T.
AU  - Kamp-Becker,
AU  - I.
AU  - Christiansen,
AU  - H.
AU  - Weber,
AU  - L.
DA  - September
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0202855
DP  - Ovid Technologies
KW  - article
KW  - attention deficit disorder/th [Therapy]
KW  - behavior change
KW  - behavior disorder/th [Therapy]
KW  - behavior therapy
KW  - child behavior
KW  - conduct disorder/th [Therapy]
KW  - follow up
KW  - human
KW  - information processing
KW  - meta analysis
KW  - oppositional defiant disorder/th [Therapy]
KW  - quality control
KW  - systematic error
KW  - systematic review
KW  - treatment outcome
KW  - externalizing behavior disorder/th [Therapy]
KW  - parent based intervention
L1  - internal-pdf://1694345919/Mingebach-2018-Meta-meta-analysis on the effec.pdf
LA  - English
PY  - 2018
T2  - PLoS ONE
TI  - Meta-meta-analysis on the effectiveness of parent-based interventions for the treatment of child externalizing behavior problems
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0202855&amp;type=printable
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=624020694
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1371%2Fjournal.pone.0202855&amp;issn=1932-6203&amp;isbn=&amp;volume=13&amp;issue=9&amp;spage=e0202855&amp;pages=&amp;date=2018&amp;title=PLoS+ONE&amp;atitle=Meta-meta-analysis+on+the+effectiveness+of+parent-based+interventions+for+the+treatment+of+child+externalizing+behavior+problems&amp;aulast=Mingebach&amp;pid=%3Cauthor%3EMingebach+T.%3C%2Fauthor%3E%3CAN%3E624020694%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
VL  - 13 (9) (no pagination)
ER  -
TY  - JOUR
AB  - Anxiety and depression are among the most common mental health issues experienced in childhood. Implementing school-based prevention programs during childhood, rather than adolescence, is thought to provide better mental health outcomes. The present meta-analysis aimed to investigate the efficacy of universal school-based prevention programs that target both anxiety and depression in children (aged 13 years or below), and examine three moderators (i.e., program type, primary target of program, and number of sessions) on prevention effects. PsycINFO, PubMED, and Google Scholar were systematically searched for relevant articles published up to and including January 2018. 

Fourteen randomised controlled trials, consisting of 5970 children, met eligibility criteria. Prevention programs led to significantly fewer depressive symptoms at post-program (g = 0.172) and at long-term follow-up periods (g = 0.180), but not at short-term follow-up. Programs were not found to prevent anxiety symptoms across any time point. Considerable heterogeneity was observed for all effects. 

Program type and length were found to moderate the relationship between prevention program and outcomes. Prevention programs were effective in preventing depressive symptoms at post-program and long-term follow-up, while no significant preventative effect on anxiety symptoms was observed. 

The FRIENDS Program and programs which contained a greater number of sessions showed beneficial effects on anxiety and depressive symptoms. Universal programs aimed at preventing both anxiety and depression in children are limited. Future research should investigate the long-term evaluation of school-based prevention programs for anxiety and depression in children.
AD  - Johnstone, Kristy M. School of Psychology, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia. kristy.johnstone@flinders.edu.au.Kemps, Eva. School of Psychology, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia.Chen, Junwen. School of Psychology, Flinders University, GPO Box 2100, Adelaide, SA, 5001, Australia.
AN  - 30105480
AU  - Johnstone,
AU  - K.
AU  - M.
AU  - Kemps,
AU  - E.
AU  - Chen,
AU  - J.
DA  - Aug 14
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-018-0266-5
DP  - Ovid Technologies
J2  - Clin Child Fam Psychol Rev
L1  - internal-pdf://1878068512/Johnstone-2018-A Meta-Analysis of Universal Sc.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingAugJohnstone, Kristy MKemps, EvaChen, Junwen
PY  - 2018
SP  - 14
T2  - Clinical Child &amp; Family Psychology Review
TI  - A Meta-Analysis of Universal School-Based Prevention Programs for Anxiety and Depression in Children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30105480
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30105480&amp;id=doi:10.1007%2Fs10567-018-0266-5&amp;issn=1096-4037&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Clinical+Child+%26+Family+Psychology+Review&amp;atitle=A+Meta-Analysis+of+Universal+School-Based+Prevention+Programs+for+Anxiety+and+Depression+in+Children.&amp;aulast=Johnstone&amp;pid=%3Cauthor%3EJohnstone+KM%3C%2Fauthor%3E%3CAN%3E30105480%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10567-018-0266-5
VL  - 14
ER  -
TY  - JOUR
AB  - This article updates the evidence base on outpatient behavioral treatments for adolescent substance use (ASU) since publication of the previous review completed for this journal by Hogue, Henderson, Ozechowski, and Robbins (2014). It first summarizes the Hogue et al. findings along with those from recent literature reviews and meta-analytic studies of ASU treatments. 

It then presents study design and methods criteria used to select 11 comparative studies subjected to Journal of Clinical Child and Adolescent Psychology level of support evaluation. These 11 studies are detailed in terms of their sample characteristics, methodological quality, and substance use outcomes. 

Cumulative level of support designations are then made for each identified treatment approach. These cumulative designations are virtually identical to those of the previous review: ecological family-based treatment, individual cognitive-behavioral therapy, and group cognitive-behavioral therapy remain well-established; behavioral family-based treatment and motivational interviewing remain probably efficacious; drug counseling remains possibly efficacious; and an updated total of 5 multicomponent treatments combining more than 1 approach (3 of which include contingency management) are deemed well-established or probably efficacious. Treatment delivery issues associated with evidence-based approaches are then reviewed, focusing on client engagement, fidelity and mediator, and predictor and moderator effects. 

Finally, to help accelerate innovation in ASU treatment science and practice, the article outlines promising horizons in improving youth identification and access, specifying and implementing pragmatic treatment in community settings, and leveraging emerging lessons from implementation science.
AD  - Hogue, Aaron. a Center on Addiction.Henderson, Craig E. b Department of Psychology , Sam Houston State University.Becker, Sara J. c Center for Alcohol and Addictions Studies , Brown University School of Public Health.Knight, Danica K. d Institute of Behavioral Research , Texas Christian University.
AN  - 29893607
AU  - Hogue,
AU  - A.
AU  - Henderson,
AU  - C.
AU  - E.
AU  - Becker,
AU  - S.
AU  - J.
AU  - Knight,
AU  - D.
AU  - K.
DA  - Jul-Aug
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/15374416.2018.1466307
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
L1  - internal-pdf://1675212854/Hogue-2018-Evidence Base on Outpatient Behavio.pdf
LA  - English
N1  - Hogue, AaronHenderson, Craig EBecker, Sara JKnight, Danica K
PY  - 2018
SP  - 499-526
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Evidence Base on Outpatient Behavioral Treatments for Adolescent Substance Use, 2014-2017: Outcomes, Treatment Delivery, and Promising Horizons
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29893607
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29893607&amp;id=doi:10.1080%2F15374416.2018.1466307&amp;issn=1537-4416&amp;isbn=&amp;volume=47&amp;issue=4&amp;spage=499&amp;pages=499-526&amp;date=2018&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Evidence+Base+on+Outpatient+Behavioral+Treatments+for+Adolescent+Substance+Use%2C+2014-2017%3A+Outcomes%2C+Treatment+Delivery%2C+and+Promising+Horizons.&amp;aulast=Hogue&amp;pid=%3Cauthor%3EHogue+A%3C%2Fauthor%3E%3CAN%3E29893607%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/pdf/10.1080/15374416.2018.1466307?needAccess=true
VL  - 47
ER  -
TY  - JOUR
AB  - **Background**
Various intervention programs exist for parents of preterm babies and some systematic reviews (SRs) have synthesised the evidence of their effectiveness. These reviews are, however, limited to specific interventions, components, or outcomes, and a comprehensive evidence base is lacking. The aim of this meta-review was to appraise and meta-synthesise the evidence from existing SRs to provide a comprehensive evidence base on the effectiveness of interventions for parents of preterm infants on parental and infant outcomes.

**Methods**
We conducted a comprehensive search of the following databases to identify relevant SRs: Cochrane library, Web of science, EMBASE, CINAHL, British Nursing Index, PsycINFO, Medline, ScienceDirect, Scopus, IBSS, DOAJ, ERIC, EPPI-Centre, PROSPERO, WHO Library. Additional searches were conducted using authors&rsquo; institutional libraries, Google Scholar, and the reference lists of identified reviews. Identified articles were screened in two stages against an inclusion criteria with titles and abstracts screened first followed by full-text screening. Selected SRs were appraised using the AMSTAR tool. Extracted data using a predesigned tool were synthesised narratively examining the direction of impact on outcomes.

**Results**
We found 11 SRs eligible for inclusion that synthesised a total of 343 quantitative primary studies. The average quality of the SRs was &lsquo;medium&rsquo;. Thirty four interventions were reported across the SRs with considerable heterogeneity in the structural framework and the targeted outcomes that included maternal-infant dyadic, maternal/parental, and infant outcomes. Among all interventions, Kangaroo Care (KC) showed the most frequent positive impact across outcomes (n&thinsp;=&thinsp;19) followed by Mother Infant Transaction Program (MITP) (n&thinsp;=&thinsp;14). Other interventions with most consistent positive impact on infant outcomes were Modified-Mother Infant Transaction Program (M-MITP) (n&thinsp;=&thinsp;6), Infant Health and Development Program (IHDP) (n&thinsp;=&thinsp;5) and Creating Opportunities for Parent Empowerment (COPE) (n&thinsp;=&thinsp;5). Overall, interventions with both home and facility based components showed the most frequent positive impact across outcomes.

**Conclusions**
Neonatal care policy and planning for preterm babies should consider the implementation of interventions with most positive impact on outcomes. The heterogeneity in interventions and outcomes calls for the development and implementation of an integrated program for parents of preterm infants with a clearly defined global set of parental and infant outcomes.
AD  - [Puthussery, Shuby; Chutiyami, Muhammad; Tseng, Pei-Ching] Univ Bedfordshire, Inst Hlth Res, Maternal &amp; Child Hlth Res Ctr, Putteridge Bury, Hitchin Rd, Luton LU2 8LE, Beds, England. [Kilby, Lesley; Kapadia, Jogesh] Luton &amp; Dunstable Hosp, Neonatal Unit, Lewsey Rd, Luton LU4 0DZ, Beds, England.Puthussery, S (reprint author), Univ Bedfordshire, Inst Hlth Res, Maternal &amp; Child Hlth Res Ctr, Putteridge Bury, Hitchin Rd, Luton LU2 8LE, Beds, England.shuby.puthussery@beds.ac.uk
AN  - WOS:000437859400002
AU  - Puthussery,
AU  - S.
AU  - Chutiyami,
AU  - M.
AU  - Tseng,
AU  - P.
AU  - C.
AU  - Kilby,
AU  - L.
AU  - Kapadia,
AU  - J.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/s12887-018-1205-9
J2  - BMC Pediatr.
KW  - Preterm infants
KW  - Early intervention programs
KW  - Parents
KW  - Meta-review
KW  - Neonatal health
KW  - near-term infants
KW  - controlled-trial
KW  - outcomes
KW  - birth
KW  - stress
KW  - metaanalysis
KW  - quality
KW  - fathers
KW  - mothers
KW  - born
KW  - Pediatrics
L1  - internal-pdf://1445664939/Puthussery-2018-Effectiveness of early interve.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GM1UWTimes Cited: 0Cited Reference Count: 40Puthussery, Shuby Chutiyami, Muhammad Tseng, Pei-Ching Kilby, Lesley Kapadia, JogeshChutiyami, Muhammad/0000-0002-7378-63020BmcLondon
PY  - 2018
SP  - 18
T2  - Bmc Pediatrics
TI  - Effectiveness of early intervention programs for parents of preterm infants: a meta-review of systematic reviews
UR  - &lt;Go to ISI&gt;://WOS:000437859400002
UR  - https://bmcpediatr.biomedcentral.com/track/pdf/10.1186/s12887-018-1205-9
VL  - 18
ER  -
TY  - JOUR
AB  - **Background:** 
Preterm very low birth weight (VLBW) infants are at risk of gut dysbiosis and neurodevelopmental deficits. Prebiotics and probiotics may modulate gut microbiota and influence brain functions. This review synthesizes literature on effect of prebiotic and/or probiotic supplementation in preterm VLBW on their neurodevelopmental outcomes. 

**Methods:** 
Search was done using PubMed and CENTRAL. Randomized controlled trials (RCTs) in preterm infants (&lt;37 weeks gestation) and/or infants with birth weight &lt;1500 g that evaluated the effect of prebiotic and/or probiotic supplementation on neurodevelopmental outcomes were included. Weighted mean difference in cognitive and motor scores; pooled relative risks for cognitive and motor impairment, cerebral palsy, hearing, and visual impairment were estimated. Quality of evidence was assessed using the GRADE criteria. 

**Results:** 
Out of 275 articles identified, seven were included for review. All, except one, were done in preterms &lt;33 weeks of gestation. Age of assessment of outcomes was &gt;=18-22 months of corrected age in five studies. Interventions did not decrease or increase the risk of cognitive and motor impairment, cerebral palsy, visual, and hearing impairment. Quality of evidence was &quot;low&quot; to &quot;very low.&quot; 

**Conclusions:** 
Limited evidence from RCTs does not demonstrate a difference in neurodevelopmental outcomes between prebiotic/probiotic treated and untreated control groups. Copyright &copy; 2018, International Pediatric Research Foundation, Inc.
AD  - (Upadhyay, Taneja, Chowdhury, Bhandari) Centre for Health Research and Development, Society for Applied Studies, New Delhi, India (Strand) Department of Research, Innlandet Hospital Trust, Brumunddal, NorwayR.P. Upadhyay, Centre for Health Research and Development, Society for Applied Studies, New Delhi, India. E-mail: ravi.upadhyay@sas.org.in
AN  - 624573878
AU  - Upadhyay,
AU  - R.
AU  - P.
AU  - Taneja,
AU  - S.
AU  - Chowdhury,
AU  - R.
AU  - Strand,
AU  - T.
AU  - A.
AU  - Bhandari,
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1038/s41390-018-0211-9
DP  - Ovid Technologies
KW  - article
KW  - cerebral palsy
KW  - clinical assessment
KW  - cognitive defect
KW  - drug combination
KW  - drug therapy
KW  - female
KW  - hearing impairment
KW  - human
KW  - infant
KW  - male
KW  - Medline
KW  - meta analysis
KW  - nervous system development
KW  - pregnancy
KW  - prematurity
KW  - randomized controlled trial (topic)
KW  - risk assessment
KW  - risk factor
KW  - systematic review
KW  - very low birth weight
KW  - visual impairment
KW  - prebiotic agent
KW  - probiotic agent
L1  - internal-pdf://2975436323/Upadhyay-2018-Effect of prebiotic and probioti.pdf
LA  - English
M3  - In Press
N1  - Using Smart Source ParsingDate of Publication: 2018
PY  - 2018
T2  - Pediatric Research.
TI  - Effect of prebiotic and probiotic supplementation on neurodevelopment in preterm very low birth weight infants: findings from a meta-analysis
UR  - http://www.nature.com/pr/index.html
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=624573878
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1038%2Fs41390-018-0211-9&amp;issn=0031-3998&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Pediatric+Research&amp;atitle=Effect+of+prebiotic+and+probiotic+supplementation+on+neurodevelopment+in+preterm+very+low+birth+weight+infants%3A+findings+from+a+meta-analysis&amp;aulast=Upadhyay&amp;pid=%3Cauthor%3EUpadhyay+R.P.%3C%2Fauthor%3E%3CAN%3E624573878%3C%2FAN%3E%3CDT%3EArticle+In+Press%3C%2FDT%3E
UR  - https://www.nature.com/articles/s41390-018-0211-9
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
Results from studies evaluating the effectiveness of focused psychosocial support interventions in children exposed to traumatic events in humanitarian settings in low-income and middle-income countries have been inconsistent, showing varying results by setting and subgroup (eg, age or gender). We aimed to assess the effectiveness of these interventions, and to explore which children are likely to benefit most.

**METHODS:**
We did a systematic review and meta-analysis of individual participant data (IPD) from 3143 children recruited to 11 randomised controlled trials of focused psychosocial support interventions versus waiting list. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, PubMed, PsycArticles, Web of Science, and the main local low-income and middle-income countries (LMICs) databases according to the list of databases relevant to LMIC developed collaboratively by Cochrane and WHO Library, up to November, 2016. We included randomised controlled trials that assessed the effectiveness of focused psychosocial support interventions in children exposed to traumatic events in LMICs, compared with waiting lists (eg, inactive controls). We excluded quasi-randomised trials, studies that did not focus on psychosocial support interventions, and studies that compared two active interventions without control conditions. We requested anonymised data from each trial for each of the prespecified variables for each child who was randomly assigned. The main outcomes considered were continuous scores in post-traumatic stress disorder (PTSD) symptoms, depressive symptoms, and anxiety symptoms assessed with rating scales administered immediately (0-4 weeks) after the intervention. We harmonised all individual items from rating scales using item response theory methods. This study is registered with PROSPERO, number CRD42013006960.

**FINDINGS:**
We identified a beneficial effect of focused psychosocial support interventions on PTSD symptoms (standardised mean difference [SMD] -0&middot;33, 95% CI -0&middot;52 to -0&middot;14) that was maintained at follow-up (-0&middot;21, -0&middot;42 to -0&middot;01). We also identified benefits at the endpoint for functional impairment (-0&middot;29, -0&middot;43 to -0&middot;15) and for strengths: coping (-0&middot;22, -0&middot;43 to -0&middot;02), hope (-0&middot;29, -0&middot;48 to -0&middot;09), and social support (-0&middot;27, -0&middot;52 to -0&middot;02). In IPD meta-analyses focused on age, gender, displacement status, region, and household size we found a stronger improvement in PTSD symptoms in children aged 15-18 years (-0&middot;43, -0&middot;63 to -0&middot;23), in non-displaced children (-0&middot;40, -0&middot;52 to -0&middot;27), and in children living in smaller households (&lt;6 members; -0&middot;27, -0&middot;42 to -0&middot;11).

**INTERPRETATION:**
Overall, focused psychosocial interventions are effective in reducing PTSD and functional impairment, and in increasing hope, coping, and social support. Future studies should focus on strengthening interventions for younger children, displaced children, and children living in larger households.

**FUNDING:**
European Commission FP7th Framework Programme for Research (Marie Curie International Outgoing Fellowship) and the National Institute on Aging.

Copyright &copy; 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license. Published by Elsevier Ltd.. All rights reserved.
AN  - WOS:000427125900020
AU  - Purgato,
AU  - M.
AU  - Gross,
AU  - A.
AU  - L.
AU  - Betancourt,
AU  - T.
AU  - Bolton,
AU  - P.
AU  - Bonetto,
AU  - C.
AU  - Gastaldon,
AU  - C.
AU  - Gordon,
AU  - J.
AU  - O&#039;Callaghan,
AU  - P.
AU  - Papola,
AU  - D.
AU  - Peltonen,
AU  - K.
AU  - Punamaki,
AU  - R.
AU  - L.
AU  - Richards,
AU  - J.
AU  - Staples,
AU  - J.
AU  - K.
AU  - Unterhitzenberger,
AU  - J.
AU  - van
AU  - Ommeren,
AU  - M.
AU  - de
AU  - Jong,
AU  - J.
AU  - Jordans,
AU  - M.
AU  - J.
AU  - D.
AU  - Tol,
AU  - W.
AU  - A.
AU  - Barbui,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/S2214-109X(18)30046-9
L1  - internal-pdf://2216226068/Purgato_2018.pdf
PY  - 2018
SP  - E390-E400
T2  - Lancet Global Health
TI  - Focused psychosocial interventions for children in low-resource humanitarian settings: a systematic review and individual participant data meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000427125900020
UR  - https://www.sciencedirect.com/science/article/pii/S2214109X18300469?via%3Dihub
VL  - 6
ER  -
TY  - JOUR
AB  - **OBJECTIVE. **
The purpose of this systematic review was to describe the evidence for the effectiveness of early intervention to improve and maintain performance in occupations for youths with or at risk for serious mental illness (SMI). 

**METHOD. **
Titles and abstracts of 670 articles were reviewed, 234 were retrieved for full review, and 30 met inclusion criteria. 

**RESULTS. **
Moderate to strong evidence supports cognitive remediation (CR) and mixed evidence supports cognitive-behavioral therapy (CBT) as an adjunct modality to improve general functioning. Moderate to strong evidence supports use of supported employment and supported education (SE/E) to improve social and occupational outcomes in employment and academics. Strong evidence supports family psychoeducation (FPE) to prevent relapse and rehospitalization and improve problem-solving skills and general functioning. 

**CONCLUSION. **
Occupational therapy practitioners should integrate CR, SE/E, and FPE into early intervention with youth with or at risk for SMI. In addition, CBT is an effective modality for use with this population.
AD  - [Read, Halley; Roush, Sean] Pacific Univ, Sch Occupat Therapy, Forest Grove, OR 97116 USA. [Downing, Donna] Maine Med Ctr, Portland, ME 04102 USA.Read, H (reprint author), Pacific Univ, Sch Occupat Therapy, Forest Grove, OR 97116 USA.readh@pacificu.edu
AN  - WOS:000443129300006
AU  - Read,
AU  - H.
AU  - Roush,
AU  - S.
AU  - Downing,
AU  - D.
DA  - Sep-Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.5014/ajot.2018.033118
J2  - Am. J. Occup. Ther.
KW  - randomized controlled-trial
KW  - cognitive-behavioral therapy
KW  - 1st episode
KW  - psychosis
KW  - clinical high-risk
KW  - 1st-episode psychosis
KW  - follow-up
KW  - individual placement
KW  - prevention program
KW  - people
KW  - depression
KW  - Rehabilitation
L1  - internal-pdf://1772954440/Read-2018-Early Intervention in Mental Health.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GR9WZTimes Cited: 1Cited Reference Count: 43Read, Halley Roush, Sean Downing, Donna12Amer occupational therapy assoc, incBethesda1943-7676
PY  - 2018
SP  - 8
T2  - American Journal of Occupational Therapy
TI  - Early Intervention in Mental Health for Adolescents and Young Adults: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000443129300006
UR  - http://ajot.aota.org/article.aspx?articleid=2696275
VL  - 72
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
Autism spectrum disorder (ASD) has an estimated prevalence of around 1.7% of the population. People with ASD often also have language difficulties, and about 25% to 30% of children with ASD either fail to develop functional language or are minimally verbal. The ability to communicate effectively is an essential life skill, and difficulties with communication can have a range of adverse outcomes, including poorer academic achievement, behavioural difficulties and reduced quality of life. Historically, most studies have investigated communication interventions for ASD in verbal children. We cannot assume the same interventions will work for minimally verbal children with ASD.

**OBJECTIVES:**
To assess the effects of communication interventions for ASD in minimally verbal children.

**SEARCH METHODS:**
We searched CENTRAL, MEDLINE and Embase as well as 12 other databases and three trials registers in November 2017. We also checked the reference lists of all included studies and relevant reviews, contacting experts in the field as well as authors of identified studies about other potentially relevant ongoing and unpublished studies.

**SELECTION CRITERIA:**
Randomised controlled trials (RCTs) of communication-focused interventions for children (under 12 years of age) diagnosed with ASD and who are minimally verbal (fewer than 30 functional words or unable to use speech alone to communicate), compared with no treatment, wait-list control or treatment as usual.

**DATA COLLECTION AND ANALYSIS:**
We used standard Cochrane methodological procedures.

**MAIN RESULTS:**
This review includes two RCTs (154 children aged 32 months to 11 years) of communication interventions for ASD in minimally verbal children compared with a control group (treatment as usual). One RCT used a verbally based intervention (focused playtime intervention; FPI) administered by parents in the home, whereas the other used an alternative and augmentative communication (AAC) intervention (Picture Exchange Communication System; PECS) administered by teachers in a school setting.The FPI study took place in the USA and included 70 participants (64 boys) aged 32 to 82 months who were minimally verbal and had received a diagnosis of ASD. This intervention focused on developing coordinated toy play between child and parent. Participants received 12 in-home parent training sessions for 90 minutes per session for 12 weeks, and they were also invited to attend parent advocacy coaching sessions. This study was funded by the National Institute of Child Health and Human Development, the MIND Institute Research Program and a Professional Staff Congress-City University of New York grant. The PECS study included 84 minimally verbal participants (73 boys) aged 4 to 11 years who had a formal diagnosis of ASD and who were not using PECS beyond phase 1 at baseline. All children attended autism-specific classes or units, and most classes had a child to adult ratio of 2:1. Teachers and parents received PECS training (two-day workshop). PECS consultants also conducted six half-day consultations with each class once per month over five months. This study took place in the UK and was funded by the Three Guineas Trust.Both included studies had high or unclear risk of bias in at least four of the seven &#039;Risk of bias&#039; categories, with a lack of blinding for participants and personnel being the most problematic area. Using the GRADE approach, we rated the overall quality of the evidence as very low due to risk of bias, imprecision (small sample sizes and wide confidence intervals) and because there was only one trial identified per type of intervention (i.e. verbally based or AAC).Both studies focused primarily on communication outcomes (verbal and non-verbal). One of the studies also collected information on social communication. The FPI study found no significant improvement in spoken communication, measured using the expressive language domain of the Mullen Scale of Early Learning expressive language, at postintervention. However, this study found that children with lower expressive language at baseline (less than 11.3 months age-equivalent) improved more than children with better expressive language and that the intervention produced expressive language gains in some children. The PECS study found that children enrolled in the AAC intervention were significantly more likely to use verbal initiations and PECS symbols immediately postintervention; however, gains were not maintained 10 months later. There was no evidence that AAC improved frequency of speech, verbal expressive vocabulary or children&#039;s social communication or pragmatic language immediately postintervention. Overall, neither of the interventions (PECS or FPI) resulted in maintained improvements in spoken or non-verbal communication in most children.Neither study collected information on adverse events, other communication skills, quality of life or behavioural outcomes.

**AUTHORS&#039; CONCLUSIONS:**
There is limited evidence that verbally based and ACC interventions improve spoken and non-verbal communication in minimally verbal children with ASD. A substantial number of studies have investigated communication interventions for minimally verbal children with ASD, yet only two studies met inclusion criteria for this review, and we considered the overall quality of the evidence to be very low. In the study that used an AAC intervention, there were significant gains in frequency of PECS use and verbal and non-verbal initiations, but not in expressive vocabulary or social communication immediately postintervention. In the study that investigated a verbally based intervention, there were no significant gains in expressive language postintervention, but children with lower expressive language at the beginning of the study improved more than those with better expressive language at baseline. Neither study investigated adverse events, other communication skills, quality of life or behavioural outcomes. Future RCTs that compare two interventions and include a control group will allow us to better understand treatment effects in the context of spontaneous maturation and will allow further comparison of different interventions as well as the investigation of moderating factors.
AU  - Brignell,
AU  - A.
AU  - Chenausky,
AU  - K.
AU  - V.
AU  - Song,
AU  - H.
AU  - Zhu,
AU  - J.
AU  - Suo,
AU  - C.
AU  - Morgan,
AU  - A.
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD012324.pub2.
L1  - internal-pdf://0474256745/Brignell-2018-Communication interventions for.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Communication interventions for autism spectrum disorder in minimally verbal children
ER  -
TY  - JOUR
AB  - **AIM: **
Attenuated psychotic symptoms (APSs) have been the primary emphasis in youth at clinical high risk (CHR) for psychosis for assessing symptomology and determining subsequent transition to a psychotic disorder. Previous reviews primarily focused on the efficacy of cognitive behavioural therapy (CBT) on APS; however, a comprehensive assessment of other interventions to date is lacking. Therefore, we conducted a systematic review and meta-analysis of all intervention studies examining APS in CHR youth.

**METHOD: **
The authors searched Embase, CINAHL, PsycINFO, Medline and EBM from inception to May 2017. Studies were selected if they included any intervention that reported follow-up APS in youth at CHR. Interventions were evaluated and stratified by time using both pairwise and network meta-analyses (NMAs). Due to the differences in APS scales, effect sizes were calculated as Hedges g and reported as the standardized mean difference (SMD).

**RESULTS: **
Forty-one studies met our inclusion criteria. In pairwise meta-analyses, CBT was associated with a trend towards reduction in APS compared to controls at 12-months. In the NMA, integrated psychological therapy, CBT, supportive therapy, family therapy, needs-based interventions, omega-3, risperidone plus CBT and olanzapine were not significantly more effective at reducing APS at 6 and 12 months relative to any other intervention.

**CONCLUSIONS:** 
CBT demonstrated a slight trend at reducing APS at long-term follow-up compared to controls. No interventions were significantly more effective at reducing APS compared to all other interventions in the NMA. 

[Correction added on 4 June 2018, after first online publication: Some parts of the Abstract section particularly &#039;Results&#039; and &#039;Conclusions&#039; have been corrected.].
AD  - Devoe, Daniel J. Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.Farris, Megan S. Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.Townes, Parker. Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.Addington, Jean. Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.
AN  - 29749710
AU  - Devoe,
AU  - D.
AU  - J.
AU  - Farris,
AU  - M.
AU  - S.
AU  - Townes,
AU  - P.
AU  - Addington,
AU  - J.
DA  - May 11
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/eip.12677
DP  - Ovid Technologies
J2  - Early Interv Psychiatry
L1  - internal-pdf://2816012996/Devoe-2018-Attenuated psychotic symptom interv.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingMayDevoe, Daniel JFarris, Megan STownes, ParkerAddington, Jean
PY  - 2018
SP  - 11
T2  - Early intervention in psychiatry
TI  - Attenuated psychotic symptom interventions in youth at risk of psychosis: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29749710
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29749710&amp;id=doi:10.1111%2Feip.12677&amp;issn=1751-7885&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Early+intervention+in+psychiatry&amp;atitle=Attenuated+psychotic+symptom+interventions+in+youth+at+risk+of+psychosis%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Devoe&amp;pid=%3Cauthor%3EDevoe+DJ%3C%2Fauthor%3E%3CAN%3E29749710%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/eip.12677
VL  - 11
ER  -
TY  - JOUR
AB  - **Background: **
Mindfulness as a positive mental health intervention approach has been increasingly applied to address depression in young people. This systematic review and meta-analysis evaluated the effects of mindfulness-based stress reduction (MBSR) in the treatment of depression among adolescents and young adults. 

**Methods: **
Electronic databases and references in articles were searched. Randomized controlled trials (RCTs) evaluating MBSR and reporting outcomes for depressive symptoms among young people aged 12 to 25 years were included. Data extraction and risk of bias assessment were conducted by two reviewers independently. Hedges&#039; g with a 95% confidence interval was calculated to represent intervention effect. 

**Results: **
Eighteen RCTs featuring 2,042 participants were included in the meta-analysis. Relative to the control groups (e.g., no treatment, treatment as usual, or active control), MBSR had moderate effects in reducing depressive symptoms at the end of intervention (Hedges&#039; g = -0.45). No statistically significant effects were found in follow-up (Hedges&#039; g = -0.24) due to a lack of statistical power. Meta-regression found that the average treatment effect might be moderated by control condition, treatment duration, and participants&#039; baseline depression. 

**Conclusion: **
MBSR had moderate effects in reducing depression in young people at posttest. Future research is needed to assess the follow-up effects of MBSR on depressive symptoms among adolescents and young adults.
AD  - [Chi, Xinli] Shenzhen Univ, Coll Psychol &amp; Sociol, Shenzhen, Peoples R China. [Chi, Xinli] Shenzhen Univ, Shenzhen Key Lab Affect &amp; Social Cognit Sci, Shenzhen, Peoples R China. [Bo, Ai] NYU, Silver Sch Social Work, New York, NY USA. [Liu, Tingting] Wuhan Univ, Dept Sociol, Wuhan, Hubei, Peoples R China. [Zhang, Peichao] Wuhan Univ, Dept Philosophy, Res Ctr Modern Psychol, Wuhan, Hubei, Peoples R China. [Chi, Iris] Univ Southern Calif, Suzanne Dworak Peck Sch Social Work, Los Angeles, CA USA.Liu, TT (reprint author), Wuhan Univ, Dept Sociol, Wuhan, Hubei, Peoples R China.liutingtinghku@163.com
AN  - WOS:000435856400001
AU  - Chi,
AU  - X.
AU  - L.
AU  - Bo,
AU  - A.
AU  - Liu,
AU  - T.
AU  - T.
AU  - Zhang,
AU  - P.
AU  - C.
AU  - Chi,
AU  - I.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3389/fpsyg.2018.01034
J2  - Front. Psychol.
KW  - mindfulness-based stress reduction
KW  - adolescents
KW  - young adults
KW  - randomized controlled trials
KW  - depressive symptoms
KW  - meta-regression
KW  - randomized controlled-trial
KW  - robust variance-estimation
KW  - statistical
KW  - tests
KW  - mental-health
KW  - students
KW  - symptoms
KW  - program
KW  - meditation
KW  - children
KW  - efficacy
KW  - Psychology
L1  - internal-pdf://2832920049/Chi-2018-Effects of Mindfulness-Based Stress R.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GK1ELTimes Cited: 0Cited Reference Count: 79Chi, Xinli Bo, Ai Liu, Tingting Zhang, Peichao Chi, IrisYoung Teacher Foundation - Humanity and Social Science of Shenzhen University [16NFC47]; National Social Science Foundation [16CSH049]; Key Project of Education Science - Shenzhen Education Bureau [dfz17006]; Youth Research Project - independent research funds (Humanities and Social Sciences) of Wuhan University [410500049]; Researcher Team Building Project - Wuhan University Humanities and Social Sciences Academic Development Program for Young Scholars [Whu2016019]The preparation of this paper was financially supported by the Young Teacher Foundation supported by Humanity and Social Science of Shenzhen University (Grant No. 16NFC47), the National Social Science Foundation (Grant No. 16CSH049), Key Project of Education Science supported by Shenzhen Education Bureau (Grant No. dfz17006), the Youth Research Project supported by independent research funds (Humanities and Social Sciences) of Wuhan University (Grant No. 410500049), and the Researcher Team Building Project supported by Wuhan University Humanities and Social Sciences Academic Development Program for Young Scholars (Grant No. Whu2016019).02Frontiers media saLausanne
PY  - 2018
SP  - 11
T2  - Frontiers in Psychology
TI  - Effects of Mindfulness-Based Stress Reduction on Depression in Adolescents and Young Adults: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000435856400001
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/361432/pubmed-zip/.versions/1/.package-entries/fpsyg-09-01034/fpsyg-09-01034.pdf?sv=2015-12-11&amp;sr=b&amp;sig=tCAWOuxfoaxav%2BZCLqxcW8eHj3SNyC%2F4fL56z7OCL1w%3D&amp;se=2018-08-02T14%3A04%3A07Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyg-09-01034.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - There is little evidence regarding the effects of individual and group intervention for children with autism spectrum disorder (ASD) on important outcomes. We performed meta-analyses using a random effects model to investigate the effectiveness of the individual and group intervention studies and to compare the effectiveness of these two types if possible. 

The main analysis which excluded studies at a high risk of bias (Analysis I) included 14 randomised controlled trials targeting children with ASD6 years of age (594 children). The results suggested that both individual and group interventions showed significant effects compared to the control condition on &quot;reciprocity of social interaction towards others&quot; (standard mean difference[SMD] [95%confidence interval(CI)] = 0.59[0.25, 0.93], p = 0.16; 0.45 [0.02, 0.88], p = 0.39, respectively). 

Only individual interventions showed significant effects compared to the control condition on &quot;parental synchrony&quot; (SMD [95%CI] = 0.99 [0.70, 1.29], p&lt;0.01). Our results showed no significant differences between individual and group interventions in effects on &quot;autism general symptoms&quot; (no study available for group intervention), &quot;developmental quotient&quot; (no study available for group intervention), &quot;expressive language&quot; (p = 0.56), &quot;receptive language&quot; (p = 0.29), &quot;reciprocity of social interaction towards others&quot; (p = 0.62), or &quot;adaptive behaviour&quot; (p = 0.43). 

We also performed sensitivity analyses including studies that had been excluded due to being at a high risk of potential bias (Analysis II). The results suggested that &quot;reciprocity of social interactions towards others&quot; showed significant effects for individual intervention compared to the control condition (0.50[0.31,0.69], p&lt;0.001) but not for group intervention (0.23[-0.33, 0.78], p = 0.42). Individual intervention also showed significant effects on &quot;parental synchrony&quot; (0.98[0.30,1.66], p = 0.005) in the sensitivity analysis. 

The results also suggested no significant difference on all the outcomes between the individual and group interventions. We also reanalysed the data using clusterrobust standard errors as sensitivity analyses (Analysis III). Analysis III showed no significant effects in the intervention condition compared to the control condition on all the outcomes for both individual and group interventions. 

When Analysis II was reanalysed using clusterrobust standard errors (Analysis IV), individual interventions showed significant effects compared to the control condition on &quot;reciprocity of social interaction towards others&quot; and &quot;parental synchrony&quot; (mean estimate[95%CI], robust standard error, p = 0.50[0.20, 0.81], 0.13, 0.006; and 1.06[0.08, 2.05], 0.42, 0.04, respectively), and none of the outcomes showed significant effects under the intervention condition compared to the control condition for group interventions. 

The discrepancies in the results between the main analysis (Analysis I) and the sensitivity analyses (Analyses II, III, and IV) may be due to the small number of included studies. Since the outcome of &quot;reciprocity of social interaction towards others&quot; can be a dependent variable that is usually measured in a context-bound setting with the child&#039;s parent, we cannotconclude that individual interventions for pre-school children with ASD have significant effects on generalised skills for engaging in reciprocal interactions with others, even if the interventions have significant effects on the outcome. 

However, the outcomes of &quot;reciprocity of social interaction towards others&quot; may be promising targets for both individual and group interventions involving pre-school children with ASD. &quot;Parental synchrony&quot; may also be a promising target for individual interventions.

Copyright &copy; 2018 Tachibana et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AD  - (Tachibana, Kobayashi) Division of Infant and Toddler Mental Health, Department of Psychosocial Medicine, National Centre for Child Health and Development, Tokyo, Japan (Tachibana) Smart Aging International Research Center, IDAC, Tohoku University, Sendai, Japan (Tachibana, Kamio) Department of Child and Adolescent Mental Health, National Center for Neurology and Psychiatry, Tokyo, Japan (Miyazaki, Mori) Department of Health Policy, National Research Institute for Child Health and Development, Tokyo, Japan (Mikami) Department of Biostatistics, Clinical Research Centre, National Centre for Child Health and Development, Tokyo, Japan (Ota) Department of Global Health Nursing, Graduate School of Nursing Science, St. Luke&#039;s International University, Tokyo, Japan (Hwang) Department of Education, Tohoku Fukushi University, Sendai, Japan (Terasaka) Department of Educational Collaboration, Osaka Kyoiku University, Osaka, Japan (Kobayashi) TELL Counseling, Tokyo, JapanY. Tachibana, Division of Infant and Toddler Mental Health, Department of Psychosocial Medicine, National Centre for Child Health and Development, Tokyo, Japan. E-mail: tachibana-y@ncchd.go.jp
AN  - 622133375
AU  - Tachibana,
AU  - Y.
AU  - Miyazaki,
AU  - C.
AU  - Mikami,
AU  - M.
AU  - Ota,
AU  - E.
AU  - Mori,
AU  - R.
AU  - Hwang,
AU  - Y.
AU  - Terasaka,
AU  - A.
AU  - Kobayashi,
AU  - E.
AU  - Kamio,
AU  - Y.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0196272
DP  - Ovid Technologies
KW  - adaptive behavior
KW  - analytical error
KW  - article
KW  - autism/th [Therapy]
KW  - behavior therapy
KW  - child
KW  - clinical effectiveness
KW  - cluster analysis
KW  - dependent variable
KW  - group therapy
KW  - high risk population
KW  - human
KW  - intermethod comparison
KW  - language
KW  - meta analysis
KW  - parental behavior
KW  - preschool child
KW  - randomized controlled trial (topic)
KW  - sensitivity analysis
KW  - social interaction
KW  - systematic review
KW  - treatment outcome
L1  - internal-pdf://2475044483/Tachibana-2018-Meta-analyses of individual ver.pdf
LA  - English
PY  - 2018
T2  - PLoS ONE
TI  - Meta-analyses of individual versus group interventions for pre-school children with autism spectrum disorder (ASD)
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0196272&amp;type=printable
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=622133375
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1371%2Fjournal.pone.0196272&amp;issn=1932-6203&amp;isbn=&amp;volume=13&amp;issue=5&amp;spage=e0196272&amp;pages=&amp;date=2018&amp;title=PLoS+ONE&amp;atitle=Meta-analyses+of+individual+versus+group+interventions+for+pre-school+children+with+autism+spectrum+disorder+%28ASD%29&amp;aulast=Tachibana&amp;pid=%3Cauthor%3ETachibana+Y.%3C%2Fauthor%3E%3CAN%3E622133375%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
VL  - 13 (5) (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Maternal physical activity (PA) during pregnancy could affect offspring&#039;s neurodevelopment. However, studies in humans in early childhood are scarce and show inconsistent results. We aimed to review the literature on the association between physical activity during pregnancy and offspring neurodevelopment. 

**METHODS: **
LILACS, MEDLINE and Web of Science were searched for studies published since 1977. Original studies conducted in humans, without language, country, or study type restriction, were eligible. Information on the study methodology like study design, sample size, PA exposure and neurodevelopment assessment, covariates, and the effect measure were extracted from the selected articles. 

**RESULTS: **
From 802 non-duplicated titles initially located, 6 articles were selected and included (one randomised clinical trial and 5 cohort studies). The instruments used to measure PA during pregnancy and neurodevelopment varied between the studies. PA was self-reported at different gestational ages and neurodevelopment was assessed prospectively in offspring aged 1-8 years old. Only the randomised clinical trial found no effect of PA over offspring neurodevelopment. Cohort studies found a positive association between PA practice during pregnancy and offspring neurodevelopment. 

**CONCLUSIONS: **
These findings suggest that leisure-time physical activity practice may have positive association with language offspring&#039;s neurodevelopment in the age range of 18 from 60 months.
AN  - 29727034
AU  - Nino
AU  - Cruz,
AU  - G.
AU  - I.
AU  - Ramirez
AU  - Varela,
AU  - A.
AU  - da
AU  - Silva,
AU  - I.
AU  - C.
AU  - M.
AU  - Hallal,
AU  - P.
AU  - C.
AU  - Santos,
AU  - I.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/ppe.12472
L1  - internal-pdf://3126722743/Nino Cruz-2018-Physical activity during pregna.pdf
PY  - 2018
SP  - 369-379
T2  - Paediatric and Perinatal Epidemiology
TI  - Physical activity during pregnancy and offspring neurodevelopment: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=29727034
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/ppe.12472
VL  - 32
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To review and assess effectiveness of sport and dance participation on subjective well-being outcomes among healthy young people aged 15-24 years.

**DESIGN: **
Systematic review.

**METHODS: **
We searched for studies published in any language between January 2006 and September 2016 on PsychINFO, Ovid MEDLINE, Eric, Web of Science (Arts and Humanities Citation Index, Social Science and Science Citation Index), Scopus, PILOTS, CINAHL, SPORTDiscus and International Index to Performing Arts. Additionally, we searched for unpublished (grey) literature via an online call for evidence, expert contribution, searches of key organisation websites and the British Library EThOS database, and a keyword Google search. Published studies of sport or dance interventions for healthy young people aged 15-24 years where subjective well-being was measured were included. Studies were excluded if participants were paid professionals or elite athletes, or if the intervention was clinical sport/dance therapy. Two researchers extracted data and assessed strength and quality of evidence using criteria in the What Works Centre for Wellbeing methods guide and GRADE, and using standardised reporting forms. Due to clinical heterogeneity between studies, meta-analysis was not appropriate. Grey literature in the form of final evaluation reports on empirical data relating to sport or dance interventions were included.

**RESULTS: **
Eleven out of 6587 articles were included (7 randomised controlled trials and 1 cohort study, and 3 unpublished grey evaluation reports). Published literature suggests meditative physical activity (yoga and Baduanjin Qigong) and group-based or peer-supported sport and dance has some potential to improve subjective well-being. Grey literature suggests sport and dance improve subjective well-being but identify negative feelings of competency and capability. The amount and quality of published evidence on sport and dance interventions to enhance subjective well-being is low.

**CONCLUSIONS: **
Meditative activities, group and peer-supported sport and dance may promote subjective well-being enhancement in youth. Evidence is limited. Better designed studies are needed.

**TRIAL REGISTRATION NUMBER: **
CRD42016048745; Results.
AD  - Mansfield, Louise. Department of Life Sciences, Division of Sport Health and Exercise Sciences, Brunel University London, Uxbridge, UK.Kay, Tess. Life Sciences, Brunel University London, Uxbridge, UK.Meads, Catherine. Health, Social Care and Education, Anglia Ruskin University, Cambridge, UK.Grigsby-Duffy, Lily. Life Sciences, Brunel University London, Uxbridge, UK.Lane, Jack. Arts and Humanities, University of Brighton, Brighton, UK.John, Alistair. Life Sciences, Brunel University London, Uxbridge, UK.Daykin, Norma. Health and Wellbeing, University of Winchester, Winchester, UK.Dolan, Paul. Social Policy, The London School of Economics and Political Science, London, UK.Testoni, Stefano. Social Policy, The London School of Economics and Political Science, London, UK.Julier, Guy. Arts and Humanities, University of Brighton, Brighton, UK.Payne, Annette. Life Sciences, Brunel University London, Uxbridge, UK.Tomlinson, Alan. Arts and Humanities, University of Brighton, Brighton, UK.Victor, Christina. Clinical Sciences, Brunel University London, Uxbridge, UK.
AN  - 30008444
AU  - Mansfield,
AU  - L.
AU  - Kay,
AU  - T.
AU  - Meads,
AU  - C.
AU  - Grigsby-Duffy,
AU  - L.
AU  - Lane,
AU  - J.
AU  - John,
AU  - A.
AU  - Daykin,
AU  - N.
AU  - Dolan,
AU  - P.
AU  - Testoni,
AU  - S.
AU  - Julier,
AU  - G.
AU  - Payne,
AU  - A.
AU  - Tomlinson,
AU  - A.
AU  - Victor,
AU  - C.
DA  - Jul 15
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmjopen-2017-020959
DP  - Ovid Technologies
J2  - BMJ Open
L1  - internal-pdf://3883931333/Mansfield-2018-Sport and dance interventions f.pdf
LA  - English
N1  - Mansfield, LouiseKay, TessMeads, CatherineGrigsby-Duffy, LilyLane, JackJohn, AlistairDaykin, NormaDolan, PaulTestoni, StefanoJulier, GuyPayne, AnnetteTomlinson, AlanVictor, Christina
PY  - 2018
SP  - e020959
T2  - BMJ Open
TI  - Sport and dance interventions for healthy young people (15-24 years) to promote subjective well-being: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30008444
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30008444&amp;id=doi:10.1136%2Fbmjopen-2017-020959&amp;issn=2044-6055&amp;isbn=&amp;volume=8&amp;issue=7&amp;spage=e020959&amp;pages=e020959&amp;date=2018&amp;title=BMJ+Open&amp;atitle=Sport+and+dance+interventions+for+healthy+young+people+%2815-24+years%29+to+promote+subjective+well-being%3A+a+systematic+review.&amp;aulast=Mansfield&amp;pid=%3Cauthor%3EMansfield+L%3C%2Fauthor%3E%3CAN%3E30008444%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082460/pdf/bmjopen-2017-020959.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering av effektene av tiltaket FRIENDS for life, et behandlingsprogram for barn og ungdommer med angst. Tiltaket er tilrettelagt for grupper, men kan også brukes individuelt. FRIENDS har som mål å hjelpe barn og ungdommer med å utvikle ferdigheter og kunnskaper som gjør dem bedre rustet til å håndtere angstprovoserende situasjoner. I Norge er RKBU Vest ansvarlig for distribusjon og implementering av tiltaket ut 2018.

METODE
Kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psycinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. To norske effektstudier er omtalt i denne oppsummeringen, samt en tredje norsk studie og en internasjonal reviewartikkel. FRIENDS er et tiltak som kan benyttes både som forebygging og behandling. Denne kunnskapsoppsummeringen er begrenset til tiltaket som behandling.

RESULTATER
Resultatene omfatter en beskrivelse av tiltaket, effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Det foreligger to norske effektstudier, hvorav den ene er en RCT med både pre-post-målinger og sammenligning med kontrollgruppe. Studien er av god forskningsmetodisk kvalitet og finner positive effekter av tiltaket i en økologisk valid setting.

KONKLUSJON
FRIENDS for life er klassifisert på nivå 4 &ndash; intervensjon med tilfredsstillende dokumentasjon
på effekt.
AU  - Sæle,
AU  - R.
AU  - G.,
AU  - Sagatun,
AU  - Å.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2018
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: FRIENDS for life (behandling)
UR  - https://ungsinn.no/post_tiltak_arkiv/friends-for-life-behandling/
VL  - 2
ER  -
TY  - JOUR
AB  - Children and adolescents with major depressive disorder (MDD) appear to be more responsive to placebo than adults in randomized placebo-controlled trials (RCTs) of second and newer generation antidepressants (SNG-AD). Previous meta-analyses obtained conflicting results regarding modifiers. We aimed to conduct a meta-analytical evaluation of placebo response rates based on both clinician-rating and self-rating scales. 

Based on the most recent and comprehensive study on adult data, we tested whether the placebo response rates in children and adolescents with MDD also increase with study duration and number of study sites. We searched systematically for published RCTs of SNG-AD in children and/or adolescents (last update: September 2017) in public domain electronic databases and additionally for documented studies in clinical trial databases. The log-transformed odds of placebo response were meta-analytically analyzed. 

The primary and secondary outcomes were placebo response rates at the end of treatment based on clinician-rating and self-rating scales, respectively. To examine the impact of study duration and number of study sites on placebo response rates, we performed simple meta-regression analyses. We selected other potential modifiers of placebo response based on significance in at least one previous pediatric meta-analysis and on theoretical considerations to perform explorative analyses. We applied sensitivity analyses with placebo response rates closest to week 8 to compare our data with those reported for adults. 

We identified 24 placebo-controlled trials (2229 patients in the placebo arms). The clinician-rated placebo response rates ranged from 22 to 62% with a pooled response rate of 45% (95% CI 41-50%). The number of study sites was a significant modifier in the simple meta-regression analysis [odds ratio (OR) 1.01, 95% CI 1.01-1.02, p = 0.0003, k = 24) with more study sites linked to a higher placebo response. Study duration was not significantly associated with the placebo response rate. The explorative simple analyses revealed that publication year may be an additional modifier. 

However, in the explorative multivariable analysis including the number of study sites and the publication year only the number of study sites reached a p value &lt;= 0.05. The self-rated placebo response rates ranged from 1 to 68% with a pooled response rate of 26% (95% CI 10-54%) (k = 6; n = 396). This meta-analysis confirms a high pooled placebo response rate in children and adolescents based on clinician ratings, which exceeds that observed in the most recent meta-analysis of placebo effects in adults (36%; 95% CI 35-37%) published in 2016. 

However, and similar to findings in adults, the pooled response rates based on self-ratings were substantially lower. In accordance with previous meta-analyses, we corroborated the number of study sites as significant modifier. In comparison to the recent adult meta-analysis, the substantially lower number of pediatric studies entails a reduced power to detect modifiers. 

Future studies should provide more precise and homogenous information to support discovery of potential modifiers and consider no-treatment-if ethically permissible-to allow differentiation between placebo and spontaneous remission rates. If these differ, practicing clinicians should facilitate placebo effects as an addition to the verum effect to maximize benefits. Further research is required to explain the discrepant response rates between clinician and self-ratings.
AN  - 30535589
AU  - Meister,
AU  - R.
AU  - Abbas,
AU  - M.
AU  - Antel,
AU  - J.
AU  - Peters,
AU  - T.
AU  - Pan,
AU  - Y.
AU  - Bingel,
AU  - U.
AU  - Nestoriuc,
AU  - Y.
AU  - Hebebrand,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00787-018-1244-7
L1  - internal-pdf://4122018475/Meister-2018-Placebo response rates and potent.pdf
PY  - 2018
SP  - 08
T2  - European Child &amp; Adolescent Psychiatry
TI  - Placebo response rates and potential modifiers in double-blind randomized controlled trials of second and newer generation antidepressants for major depressive disorder in children and adolescents: a systematic review and meta-regression analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30535589
UR  - https://link.springer.com/content/pdf/10.1007%2Fs00787-018-1244-7.pdf
VL  - 08
ER  -
TY  - JOUR
AB  - **Background**
People living in humanitarian settings in low‐ and middle‐income countries (LMICs) are exposed to a constellation of stressors that make them vulnerable to developing mental disorders. Mental disorders with a higher prevalence in these settings include post‐traumatic stress disorder (PTSD) and major depressive, anxiety, somatoform (e.g. medically unexplained physical symptoms (MUPS)), and related disorders. A range of psychological therapies are used to manage symptoms of mental disorders in this population.

**Objectives**
To compare the effectiveness and acceptability of psychological therapies versus control conditions (wait list, treatment as usual, attention placebo, psychological placebo, or no treatment) aimed at treating people with mental disorders (PTSD and major depressive, anxiety, somatoform, and related disorders) living in LMICs affected by humanitarian crises.

**Search methods**
We searched the Cochrane Common Mental Disorders Controlled Trials Register (CCMDCTR), the Cochrane Central Register of Controlled Trials (Wiley), MEDLINE (OVID), Embase (OVID), and PsycINFO (OVID), with results incorporated from searches to 3 February 2016. We also searched the World Health Organization (WHO) trials portal (ICTRP) and ClinicalTrials.gov to identify any unpublished or ongoing studies. We checked the reference lists of relevant studies and reviews.

**Selection criteria**
All randomised controlled trials (RCTs) comparing psychological therapies versus control conditions (including no treatment, usual care, wait list, attention placebo, and psychological placebo) to treat adults and children with mental disorders living in LMICs affected by humanitarian crises.

**Data collection and analysis**
We used standard Cochrane procedures for collecting data and evaluating risk of bias. We calculated standardised mean differences for continuous outcomes and risk ratios for dichotomous data, using a random‐effects model. We analysed data at endpoint (zero to four weeks after therapy); at medium term (one to four months after therapy); and at long term (six months or longer). GRADE (Grades of Recommendation, Assessment, Development, and Evaluation) was used to assess the quality of evidence for post‐traumatic stress disorder (PTSD), depression, anxiety and withdrawal outcomes.

**Main results**
We included 36 studies (33 RCTs) with a total of 3523 participants. Included studies were conducted in sub‐Saharan Africa, the Middle East and North Africa, and Asia. Studies were implemented in response to armed conflicts; disasters triggered by natural hazards; and other types of humanitarian crises. Together, the 33 RCTs compared eight psychological treatments against a control comparator.

Four studies included children and adolescents between 5 and 18 years of age. Three studies included mixed populations (two studies included participants between 12 and 25 years of age, and one study included participants between 16 and 65 years of age). Remaining studies included adult populations (18 years of age or older).

Included trials compared a psychological therapy versus a control intervention (wait list in most studies; no treatment; treatment as usual). Psychological therapies were categorised mainly as cognitive‐behavioural therapy (CBT) in 23 comparisons (including seven comparisons focused on narrative exposure therapy (NET), two focused on common elements treatment approach (CETA), and one focused on brief behavioural activation treatment (BA)); eye movement desensitisation and reprocessing (EMDR) in two comparisons; interpersonal psychotherapy (IPT) in three comparisons; thought field therapy (TFT) in three comparisons; and trauma or general supportive counselling in two comparisons. Although interventions were described under these categories, several psychotherapeutic elements were common to a range of therapies (i.e. psychoeducation, coping skills).

In adults, psychological therapies may substantially reduce endpoint PTSD symptoms compared to control conditions (standardised mean difference (SMD) ‐1.07, 95% confidence interval (CI) ‐1.34 to ‐0.79; 1272 participants; 16 studies; low‐quality evidence). The effect is smaller at one to four months (SMD ‐0.49, 95% CI ‐0.68 to ‐0.31; 1660 participants; 18 studies) and at six months (SMD ‐0.37, 95% CI ‐0.61 to ‐0.14; 400 participants; five studies). Psychological therapies may also substantially reduce endpoint depression symptoms compared to control conditions (SMD ‐0.86, 95% CI ‐1.06 to ‐0.67; 1254 participants; 14 studies; low‐quality evidence). Similar to PTSD symptoms, follow‐up data at one to four months showed a smaller effect on depression (SMD ‐0.42, 95% CI ‐0.63 to ‐0.21; 1386 participants; 16 studies). Psychological therapies may moderately reduce anxiety at endpoint (SMD ‐0.74, 95% CI ‐0.98 to ‐0.49; 694 participants; five studies; low‐quality evidence) and at one to four months&#039; follow‐up after treatment (SMD ‐0.53, 95% CI ‐0.66 to ‐0.39; 969 participants; seven studies). Dropout rates are probably similar between study conditions (19.5% with control versus 19.1% with psychological therapy (RR 0.98 95% CI 0.82 to 1.16; 2930 participants; 23 studies, moderate quality evidence)).

In children and adolescents, we found very low quality evidence for lower endpoint PTSD symptoms scores in psychotherapy conditions (CBT) compared to control conditions, although the confidence interval is wide (SMD ‐1.56, 95% CI ‐3.13 to 0.01; 130 participants; three studies;). No RCTs provided data on major depression or anxiety in children. The effect on withdrawal was uncertain (RR 1.87 95% CI 0.47 to 7.47; 138 participants; 3 studies, low quality evidence).

We did not identify any studies that evaluated psychological treatments on (symptoms of) somatoform disorders or MUPS in LMIC humanitarian settings.

**Authors&#039; conclusions**
There is low quality evidence that psychological therapies have large or moderate effects in reducing PTSD, depressive, and anxiety symptoms in adults living in humanitarian settings in LMICs. By one to four month and six month follow‐up assessments treatment effects were smaller. Fewer trials were focused on children and adolescents and they provide very low quality evidence of a beneficial effect of psychological therapies in reducing PTSD symptoms at endpoint. Confidence in these findings is influenced by the risk of bias in the studies and by substantial levels of heterogeneity. More research evidence is needed, particularly for children and adolescents over longer periods of follow‐up.
AU  - Purgato,
AU  - M.
AU  - Gastaldon,
AU  - C.
AU  - Papola,
AU  - D.
AU  - van
AU  - Ommeren,
AU  - M.
AU  - Barbui,
AU  - C.
AU  - Tol,
AU  - W.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD011849.pub2
L1  - internal-pdf://2807592521/Purgato_et_al-2018-Cochrane_Database_of_System.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological therapies for the treatment of mental disorders in low‐ and middle‐income countries affected by humanitarian crises
ER  -
TY  - JOUR
AB  - **Purpose:** 
The purpose of this meta-analysis was to investigate the effects of augmentative and alternative communication (AAC) interventions that included aided AAC input (e.g., aided AAC modeling, aided language modeling, aided language stimulation, augmented input) on communicative outcomes (both comprehension and expression) for individuals with developmental disabilities who use AAC. 

**Method:** 
A systematic search resulted in the identification of 26 single-case experimental designs (88 participants) and 2 group experimental designs (103 participants). Studies were coded in terms of participants, intervention characteristics, dependent variables, outcomes, and quality of evidence. 

**Results:** 
AAC interventions that included aided AAC input in isolation, or as part of a multicomponent intervention, were found to be highly effective across participants of various ages, disabilities, and language skills. The interventions typically included aided AAC input in conjunction with expectant delay, direct prompting (e.g., spoken, gestural), contingent responding, and openended questions. The interventions were found to be highly effective in supporting both comprehension and expression across the domains of pragmatics, semantics, and morphosyntax. Outcomes related to expression were reported more often than outcomes related to comprehension. 

**Conclusion:**
Aided AAC input may reduce input-output asymmetry and enhance expression and comprehension for individuals who use AAC; the evidence suggests that partners should utilize this strategy. Future research is needed to investigate the effects of AAC input (aided and unaided) on long-term language development for individuals who require AAC. (PsycINFO Database Record (c) 2019 APA, all rights reserved)
AD  - O&#039;Neill, Tara: tao5012@psu.eduO&#039;Neill, Tara, tao5012@psu.eduO&#039;Neill, Tara: Department of Communication Sciences and Disorders, Pennsylvania State University, University Park, PA, USLight, Janice: Department of Communication Sciences and Disorders, Pennsylvania State University, University Park, PA, USPope, Lauramarie: Department of Communication Sciences and Disorders, Pennsylvania State University, University Park, PA, US
AN  - 2019-07798-015
AU  - O&#039;Neill,
AU  - Tara
AU  - Light,
AU  - Janice
AU  - Pope,
AU  - Lauramarie
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1044/2018_JSLHR-L-17-0132
DP  - Ovid Technologies
KW  - augmentative and alternative communication, linguistic markers, complex communication needs, comprehension, oral expression, developmental disabilities
KW  - *Augmentative Communication
KW  - *Developmental Disabilities
KW  - *Language Disorders
KW  - *Linguistics
KW  - *Oral Communication
KW  - Verbal Ability
KW  - Speech &amp; Language Therapy [3385]
KW  - Human Male Female Childhood (birth-12 yrs) Preschool Age (2-5 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older) Young Adulthood (18-29 yrs) Thirties (30-39 yrs) Middle Age (40-64 yrs)
L1  - internal-pdf://3141551587/O&#039;Neill-2018.pdf
LA  - English
M3  - Meta Analysis
PY  - 2018
SP  - 1743-1765
T2  - Journal of Speech, Language, and Hearing Research
TI  - Effects of interventions that include aided augmentative and alternative communication input on the communication of individuals with complex communication needs: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2019-07798-015
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1044%2F2018_JSLHR-L-17-0132&amp;issn=1092-4388&amp;isbn=&amp;volume=61&amp;issue=7&amp;spage=1743&amp;pages=1743-1765&amp;date=2018&amp;title=Journal+of+Speech%2C+Language%2C+and+Hearing+Research&amp;atitle=Effects+of+interventions+that+include+aided+augmentative+and+alternative+communication+input+on+the+communication+of+individuals+with+complex+communication+needs%3A+A+meta-analysis.&amp;aulast=O%27Neill&amp;pid=%3Cauthor%3EO%27Neill%2C+Tara%3C%2Fauthor%3E%3CAN%3E2019-07798-015%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 61
ER  -
TY  - JOUR
AB  - **Objectives: **
Negative behavioral problems often occur following the onset of neurodevelopmental disorders and have an overall impact on the affected children, specifically in terms of their social developmental level. In children, social development behavior has been shown to spontaneously mature over time with the cognitive therapy intervention effects. This study performed a meta-analysis to provide a statistical synopsis of the available evidence of social development behavioral changes following cognitive therapy in children with neurodevelopmental disorders.

**Methods: **
Data was collected from two online search engines, including EBSCOhost and PubMed, from January 1, 2006, to August 31, 2016, using the terms &quot;cognition,&quot; &quot;cognitive function,&quot; and &quot;disease including neurodevelopmental disorder with DSM-5.&quot; Two assessors searched the literature using independent inclusion criteria and evaluated the quality of results using the Jadad score. Six articles were chosen using the Comprehensive Meta-Analysis program (version 2.0).

**Results: **
Six articles reporting randomized controlled trial studies were included. The effective scores for improving adaptive behavior following cognitive therapy in children with neurodevelopmental disorder were 0.64. The effective score of adaptive behavior was significant in this study (p &lt; 0.05). The results showed no significant statistical heterogeneity and publication bias.

**Conclusions: **
The findings of the meta-analysis suggest that cognitive interventions are effective at improving adaptive behavior associated with neurodevelopmental disorders.
AD  - Ahn, Si-Nae. Department of Occupational Therapy, Cheongju University, 298 Daesung-ro, Cheongju-si, Republic of Korea.Hwang, Sujin. Deparment of Physical Therapy, Division of Health Science, Baekseok University, 76 Munam-ro, Dongnam-gu, Cheonan-si, Chungnam, Republic of Korea.
AN  - 30297980
AU  - Ahn,
AU  - S.
AU  - N.
AU  - Hwang,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1155/2018/5029571
DP  - Ovid Technologies
J2  - Occup Ther Int
L1  - internal-pdf://2491980857/Ahn-2018-Cognitive Rehabilitation of Adaptive.pdf
LA  - English
M3  - Review
N1  - Ahn, Si-NaeHwang, Sujin
PY  - 2018
SP  - 5029571
T2  - Occupational Therapy International
TI  - Cognitive Rehabilitation of Adaptive Behavior in Children with Neurodevelopmental Disorders: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30297980
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157171/pdf/OTI2018-5029571.pdf
VL  - 2018
ER  -
TY  - JOUR
AB  - **Background**
Naloxone, a specific opioid antagonist, is available for the treatment of newborn infants with cardiorespiratory or neurological depression that may be due to intrauterine exposure to opioid. It is unclear whether newborn infants may benefit from this therapy and whether naloxone has any harmful effects.

**Objectives**
To determine the effect of naloxone on the need for and duration of neonatal unit stay in infants of mothers who received opioid analgesia prior to delivery or of mothers who have used a prescribed or non‐prescribed opioid during pregnancy.

**Search methods**
We searched the following databases in February 2018: the Cochrane Central Register of Controlled Trials (the Cochrane Library 2018, Issue 1), MEDLINE (OvidSP), MEDLINE In process &amp; Other Non‐Indexed Citations (OvidSP), Embase (OvidSP), CINAHL (EBSCO), Maternity and Infant Care (OvidSP), and PubMed. We searched for ongoing and completed trials in the WHO International Clinical Trials Registry Platform and the EU Clinical Trials Register. We checked the reference lists of relevant articles to identify further potentially relevant studies.

**Selection criteria**
Randomised controlled trials comparing the administration of naloxone versus placebo, or no drug, or another dose of naloxone to newborn infants with suspected or confirmed in utero exposure to opioid.

Data collection and analysis
We extracted data using the standard methods of Cochrane Neonatal with separate evaluation of trial quality and data extraction by two review authors and synthesis of data using risk ratio, risk difference, and mean difference.

**Main results**
We included nine trials, with 316 participants in total, that compared the effects of naloxone versus placebo or no drug in newborn infants exposed to maternal opioid analgesia prior to delivery. None of the included trials investigated infants born to mothers who had used a prescribed or non‐prescribed opioid during pregnancy. None of these trials specifically recruited infants with cardiorespiratory or neurological depression. The main outcomes reported were measures of respiratory function in the first six hours after birth. There is some evidence that naloxone increases alveolar ventilation. The trials did not assess the effect on the primary outcomes of this review (admission to a neonatal unit and failure to establish breastfeeding).

**Authors&#039; conclusions**
The existing evidence from randomised controlled trials is insufficient to determine whether naloxone confers any important benefits to newborn infants with cardiorespiratory or neurological depression that may be due to intrauterine exposure to opioid. Given concerns about the safety of naloxone in this context, it may be appropriate to limit its use to randomised controlled trials that aim to resolve these uncertainties.
AN  - CD003483
AU  - Moe‐Byrne,
AU  - T.
AU  - Brown,
AU  - J.
AU  - V.
AU  - E.
AU  - McGuire,
AU  - W.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD003483.pub3
KW  - Analgesics, Opioid [*adverse effects]
KW  - Female
KW  - Humans
KW  - Infant, Newborn
KW  - Labor Pain [drug therapy]
KW  - Naloxone [*therapeutic use]
KW  - Narcotic Antagonists [*therapeutic use]
KW  - Pregnancy
KW  - Prenatal Exposure Delayed Effects [chemically induced, *drug therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Respiratory Insufficiency [chemically induced, *drug therapy]
L1  - internal-pdf://1035876963/Moe-Byrne_et_al-2018-Cochrane_Database_of_Syst.pdf
N1  - [Neonatal]
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Naloxone for opioid‐exposed newborn infants
UR  - https://doi.org//10.1002/14651858.CD003483.pub3
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
To determine the characteristics and effectiveness of motor skill interventions in children with developmental coordination disorder (DCD) and to identify potential moderators of training effects using meta-analysis.

**DATA SOURCES: **
A search was conducted in 6 databases (CINAHL Plus, Cochrane Library, Embase, ERIC, PsycINFO, and PubMed) for articles published between 1995 and August 2017 using search items which were grouped into 3 components (motor skill interventions, DCD, and age group of interest).

**STUDY SELECTION: **
Studies were included if they recruited children 3 to 17 years of age with DCD, reported performance of motor-related skills as outcomes, were published in peer-reviewed journals, and were written in English. Qualitative synthesis was conducted for all included studies. Quantitative synthesis (meta-analysis) was only conducted for studies using a (quasi) randomized controlled trial design.

**DATA EXTRACTION: **
Methodology, participant characteristics, intervention components, outcomes, and statistically significant training effects of each included study were extracted.

**DATA SYNTHESIS: **
Sixty-six studies met the inclusion criteria with 18 of the studies eligible for meta-analysis. Motor performance and cognitive, emotional, and other psychological factors were the most common outcomes. Other 3 outcome categories included perceptions and/or satisfaction regarding the children&#039;s improvement from significant others, physical fitness, and physical activity and participation. Immediate and moderate training effects were found for motor performance (Hedges g=.63; 95% confidence interval [CI], .31-.94; P&lt;.001) and cognitive, emotional, and other psychological factors (Hedges g=0.65; 95% CI, 0.25-1.04; P=.001). Additionally, dose (minutes in total) and frequency of the intervention were significant moderators of training effect on motor performance.

**CONCLUSIONS: **
Motor skill interventions are effective in improving motor competence and performance on cognitive, emotional, and other psychological aspects in children with DCD in the short term. These effects are more robust in interventions using a large training dose and a practicing schedule of high frequency.
AD  - Yu, Jane J. Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Hong Kong.Burnett, Angus F. School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.Sit, Cindy H. Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Hong Kong. Electronic address: sithp@cuhk.edu.hk.
AN  - 29329670
AU  - Yu,
AU  - J.
AU  - J.
AU  - Burnett,
AU  - A.
AU  - F.
AU  - Sit,
AU  - C.
AU  - H.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.apmr.2017.12.009
DP  - Ovid Technologies
J2  - Arch Phys Med Rehabil
L1  - internal-pdf://2621225927/Yu-2018-Motor Skill Interventions in Children.pdf
LA  - English
M3  - Review
N1  - Yu, Jane JBurnett, Angus FSit, Cindy HS0003-9993(18)30004-2
PY  - 2018
SP  - 2076-2099
T2  - Archives of Physical Medicine &amp; Rehabilitation
TI  - Motor Skill Interventions in Children With Developmental Coordination Disorder: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29329670
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29329670&amp;id=doi:10.1016%2Fj.apmr.2017.12.009&amp;issn=0003-9993&amp;isbn=&amp;volume=99&amp;issue=10&amp;spage=2076&amp;pages=2076-2099&amp;date=2018&amp;title=Archives+of+Physical+Medicine+%26+Rehabilitation&amp;atitle=Motor+Skill+Interventions+in+Children+With+Developmental+Coordination+Disorder%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Yu&amp;pid=%3Cauthor%3EYu+JJ%3C%2Fauthor%3E%3CAN%3E29329670%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 99
ER  -
TY  - JOUR
AB  - **Objectives: **
This meta-analysis aims to study the effects of atomoxetine and methylphenidate on heart rate (HR), systolic blood pressure (SBP), and a number of adverse cardiac events on patients receiving treatment for attention-deficit hyperactive disorder (ADHD) in comparison to placebo and between atomoxetine and methylphenidate. 

**Methods: **
We searched the following databases: PubMed, EMBASE, and ScienceDirect. Meta-analysis was performed on studies that examined the relationships between methylphenidate or atomoxetine and HR, SBP, as well as a number of adverse cardiac events. These studies were either placebo-controlled or comparison studies between methylphenidate and atomoxetine. Meta-regression identified patient- and treatment-related factors that may contribute to heterogeneity. 

**Results: **
Twenty-two studies were included and the total number of participants was 46,107. Children/adolescents and adults treated with methylphenidate had more significant increases in post- vs. pre-treatment HR (p &lt; 0.001) and SBP (p &lt; 0.001) than those treated by placebo. Children and adolescents treated with atomoxetine had more significant increases post- vs. pre-treatment HR (p = 0.025) and SBP (p &lt; 0.001) than those treated with methylphenidate. Meta-regression revealed mean age of participants, mean dose, and duration of atomoxetine and methylphenidate as significant moderators that explained heterogeneity. There were no differences in the number of adverse cardiac events between participants with methylphenidate treatment and placebo or atomoxetine. 

**Conclusions:** 
Children/adolescents and adults treated with methylphenidate resulted in significant increases in post- vs. pre-treatment HR and SBP as compared to placebo. Similarly, children and adolescents treated with atomoxetine had significant increases in post- vs. pre-treatment HR and SBP than those treated with methylphenidate. These findings have potential implications for continuous monitoring of HR and SBP throughout the course of treatment although the risk for adverse cardiac events were insignificant.
AD  - [Liang, Edwin F.; Lim, Samuel Z.; Ho, Cyrus S.; Ho, Roger C.] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Psychol Med, Singapore 119228, Singapore. [Tam, Wilson W.] Natl Univ Singapore, Yong Loo Lin Sch Med, Alice Lee Ctr Nursing Studies, Singapore 119077, Singapore. [Zhang, Melvyn W.] Inst Mental Hlth, Natl Addict Management Serv, Singapore, Singapore. [McIntyre, Roger S.] Univ Hlth Network, Mood Disorders Psychopharmacol Unit, Toronto, ON M5T 1R8, Canada. [McIntyre, Roger S.] Univ Toronto, Inst Med Sci, Toronto, ON M5T 1R8, Canada. [McIntyre, Roger S.] Univ Toronto, Dept Psychiat, Toronto, ON M5T 1R8, Canada. [McIntyre, Roger S.] Univ Toronto, Dept Pharmacol, Toronto, ON M5T 1R8, Canada.Ho, RC (reprint author), Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Psychol Med, Singapore 119228, Singapore.a0105307@u.nus.edu; a0105316@u.nus.edu; nurtwsw@nus.edu.sg; su_hui_ho@nuhs.edu.sg; melvynzhangweibin@gmail.com; Roger.McIntyre@uhn.ca; pcmrhcm@nus.edu.sg
AN  - WOS:000443168200229
AU  - Liang,
AU  - E.
AU  - F.
AU  - Lim,
AU  - S.
AU  - Z.
AU  - Tam,
AU  - W.
AU  - W.
AU  - Ho,
AU  - C.
AU  - S.
AU  - Zhang,
AU  - M.
AU  - W.
AU  - McIntyre,
AU  - R.
AU  - S.
AU  - Ho,
AU  - R.
AU  - C.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3390/ijerph15081789
J2  - Int. J. Environ. Res. Public Health
KW  - methylphenidate
KW  - atomoxetine
KW  - cardiovascular system
KW  - heart rate
KW  - systolic blood pressure
KW  - meta-analysis
KW  - children
KW  - adults
KW  - placebo-controlled trial
KW  - deficit/hyperactivity disorder
KW  - open-label
KW  - release methylphenidate
KW  - cardiovascular events
KW  - oros methylphenidate
KW  - depressive symptoms
KW  - children
KW  - adolescents
KW  - stimulant
KW  - Environmental Sciences &amp; Ecology
KW  - Public, Environmental &amp; Occupational
KW  - Health
L1  - internal-pdf://2419134713/Liang-2018-The Effect of Methylphenidate and A.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GS0GQTimes Cited: 0Cited Reference Count: 58Liang, Edwin F. Lim, Samuel Z. Tam, Wilson W. Ho, Cyrus S. Zhang, Melvyn W. McIntyre, Roger S. Ho, Roger C.01MdpiBasel
PY  - 2018
SP  - 16
T2  - International Journal of Environmental Research and Public Health
TI  - The Effect of Methylphenidate and Atomoxetine on Heart Rate and Systolic Blood Pressure in Young People and Adults with Attention-Deficit Hyperactivity Disorder (ADHD): Systematic Review, Meta-Analysis, and Meta-Regression
UR  - &lt;Go to ISI&gt;://WOS:000443168200229
UR  - https://res.mdpi.com/ijerph/ijerph-15-01789/article_deploy/ijerph-15-01789-v2.pdf?filename=&amp;attachment=1
VL  - 15
ER  -
TY  - JOUR
AB  - There is increasing interest in the use of technology in supporting individuals with autism spectrum disorder (ASD). This review examined single-case studies investigating the use of technology to support self-management interventions for individuals with ASD. 

The studies were assessed against the What Works Clearinghouse standards (Institute of Education Sciences 2014) for methodological rigor. Twelve studies met inclusion criteria, and treatment effects were calculated using the percentage of non-overlapping data (Scruggs et al. Remedial and Special Education, 8(2), 24-33, 1987). 

Results showed that the use of technology to support self-management interventions is effective for individuals with ASD. Furthermore, this review highlights a need for more rigorous studies to ascertain the efficacy of the use of technology to support self-management for individuals with ASD outside school settings.
AD  - [Chia, Gladys Lai Cheng; Anderson, Angelika; McLean, Louise A.] Monash Univ, Fac Educ, Wellington Rd, Clayton, Vic 3800, Australia.Chia, GLC (reprint author), Monash Univ, Fac Educ, Wellington Rd, Clayton, Vic 3800, Australia.lai-cheng.chia@monash.edu
AN  - WOS:000432919200005
AU  - Chia,
AU  - G.
AU  - L.
AU  - C.
AU  - Anderson,
AU  - A.
AU  - McLean,
AU  - L.
AU  - A.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s40489-018-0129-5
J2  - Rev. J. Autism Dev. Disord.
KW  - Autism spectrum disorder
KW  - Self-management
KW  - Technology
KW  - Single-case
KW  - studies
KW  - single-subject research
KW  - high-functioning autism
KW  - daily living skills
KW  - on-task behavior
KW  - spectrum disorders
KW  - social-skills
KW  - developmental-disabilities
KW  - monitoring application
KW  - asperger-syndrome
KW  - video feedback
KW  - Psychology
L1  - internal-pdf://1596977031/Chia-2018-Use of Technology to Support Self-Ma.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GG8AFTimes Cited: 0Cited Reference Count: 92Chia, Gladys Lai Cheng Anderson, Angelika McLean, Louise A.0Springer heidelbergHeidelberg2195-7185
PY  - 2018
SP  - 142-155
T2  - Review Journal of Autism and Developmental Disorders
TI  - Use of Technology to Support Self-Management in Individuals with Autism: Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000432919200005
UR  - https://link.springer.com/article/10.1007%2Fs40489-018-0129-5
VL  - 5
ER  -
TY  - JOUR
AB  - Siblings of children and young people with a chronic illness are at increased risk of poor psychological functioning. 

A number of studies have attempted to implement and evaluate interventions targeting the psychological well-being of this at-risk group. This systematic review summarises the evidence regarding psychological functioning of siblings following an intervention targeting their well-being. 

The meta-analysis considered behaviour and knowledge, two of the most frequently studied outcomes. The following databases were used: PsycINFO, EMBASE, CINAHL, PubMed, Scopus and Web of Science. Seventeen studies were eligible to be included in the systematic review and eight in the meta-analysis. 

Results from the systematic review reflected the inconsistency of intervention evaluations in this area with a high level of heterogeneity and a total of 23 outcomes considered across the 17 included studies. 

The meta-analysis estimated effect sizes using a standardised mean difference (SMD) approach. Pre-post analysis suggested significant improvement in behavioural outcomes and knowledge of their sibling&#039;s health conditions with a SMD of - 0.44 [95% CI (- 0.6, - 0.29); p = 0.000] and 0.69 [(95% CI = 0.42, 0.96); p = 0.000], respectively. 

The SMD was not significant for behavioural outcomes when considering treatment-control studies. 

In conclusion, the findings suggest interventions for well-being have a positive effect on the psychological functioning of siblings of children and young people with a chronic illness, but their specificity needs to be established. There is a need for further, more methodologically robust research in this area.
AN  - 29450764
AU  - Smith,
AU  - M.
AU  - M.
AU  - Pereira,
AU  - S.
AU  - P.
AU  - Chan,
AU  - L.
AU  - Rose,
AU  - C.
AU  - Shafran,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-018-0253-x
L1  - internal-pdf://0224583809/McKenzie Smith-2018-Impact of Well-being Inter.pdf
PY  - 2018
SP  - 246-265
T2  - Clinical Child &amp; Family Psychology Review
TI  - Impact of Well-being Interventions for Siblings of Children and Young People with a Chronic Physical or Mental Health Condition: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29450764
UR  - https://link.springer.com/content/pdf/10.1007%2Fs10567-018-0253-x.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - **Background**
Long‐term physical conditions affect 10% to 12% of children and adolescents worldwide. These individuals are at greater risk of developing psychological problems, particularly anxiety and depression, sometimes directly related to their illness or medical care (e.g. health‐related anxiety). There is limited evidence regarding the effectiveness of psychological therapies for treating anxiety and depression in this population. Therapies designed for children and adolescents without medical issues may or may not be appropriate for use with those who have long‐term physical conditions.

**Objectives**
This review was undertaken to assess the effectiveness and acceptability of psychological therapies in comparison with controls (treatment‐as‐usual, waiting list, attention placebo, psychological placebo, or non‐psychological treatment) for treating anxiety and depression in children and adolescents with long‐term physical conditions.

**Search methods**
We searched Ovid MEDLINE (1950‐ ), Embase (1974‐ ), PsycINFO (1967‐ ) and the Cochrane Central Register of Controlled Trials (CENTRAL) to 27 September 2018. An earlier search of these databases was conducted via the Cochrane Common Mental Disorders Controlled Trial Register (CCMD‐CTR) (all years to May 2016). In addition, we searched the Web of Science (Core Collection) (12 October 2018) and conducted a cited reference search for reports of all included trials. We handsearched relevant conference proceedings, reference lists of included articles, and grey literature.

**Selection criteria**
Randomised controlled trials (RCTs), cluster‐randomised trials and cross‐over trials of psychological therapies for treating anxiety or depression in children with long‐term physical conditions were included.

**Data collection and analysis**
Abstracts and complete articles were independently reviewed by two authors. Discrepancies were addressed by a third author. Odds ratio (OR) was used for comparing dichotomous data and standardised mean differences (SMD) for comparing continuous data. Meta‐analysis was undertaken when treatments, participants, and the underlying clinical question were similar. Otherwise, narrative analysis of data was undertaken.

**Main results**
Twenty‐eight RCTs and one cross‐over trial with 1349 participants were included in the review. Most participants were recruited from community settings and hospital clinics in high‐income countries. For the primary outcome of treatment efficacy, short‐term depression (versus any control), there was low‐quality evidence from 16 trials involving 1121 participants suggesting that psychological therapies may be more effective than control therapies (SMD ‐0.31, 95% CI ‐0.59 to ‐0.03; I2 = 79%). For the primary outcome of treatment efficacy, short‐term anxiety (versus any control), there was inadequate evidence of moderate‐quality from 13 studies involving 578 participants to determine whether psychological therapies were more effective than control conditions (SMD ‐0.26, CI ‐0.59 to 0.07, I2 = 72%). Planned sensitivity analyses could not be undertaken for risk of bias due to the small number of trials that rated high for each domain. Additional sensitivity analysis demonstrated that psychological interventions specifically designed to reduce anxiety or depression were more effective than psychological therapies designed to improve other symptoms or general coping. There was some suggestion from subgroup analyses that they type of intervention (Chi&sup2; = 14.75, df = 5 (P = 0.01), I&sup2; = 66.1%), the severity of depression (Chi&sup2; = 23.29, df = 4 (P = 0.0001), I&sup2; = 82.8%) and the type of long‐term physical condition (Chi&sup2; = 10.55, df = 4 (P = 0.03), I&sup2; = 62.1%) may have an impact on the overall treatment effect.There was qualitative (reported), but not quantitative evidence confirming the acceptability of selected psychological therapies for anxiety and depression. There was low‐quality evidence that psychological therapies were more effective than control conditions in improving quality of life (SMD 1.13, CI 0.44 to 1.82, I2 = 89%) and symptoms of long‐term physical conditions (SMD ‐0.34, CI ‐0.6 to ‐0.06, I2 = 70%), but only in the short term. There was inadequate low‐quality evidence to determine whether psychological therapies were more effective than control conditions at improving functioning in either the short term or long term. No trials of therapies for addressing health‐related anxiety were identified and only two trials reported adverse effects; these were unrelated to psychological therapies. Overall, the evidence was of low to moderate quality, results were heterogeneous, and only one trial had an available protocol.

**Authors&#039; conclusions**
A limited number of trials of variable quality have been undertaken to assess whether psychological therapies are effective for treating anxiety and depression in children and adolescents with long‐term physical conditions. According to the available evidence, therapies specifically designed to treat anxiety or depression (especially those based on principles of cognitive behaviour therapy (CBT)) may be more likely to work in children and adolescents who have mild to moderate levels of symptoms of these disorders, at least in the short term. There is a dearth of therapies specifically designed to treat health‐related anxiety in this age group.
AU  - Thabrew,
AU  - H.
AU  - Stasiak,
AU  - K.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Donkin,
AU  - L.
AU  - Huss,
AU  - J.
AU  - H.
AU  - Highlander,
AU  - A.
AU  - Wong,
AU  - S.
AU  - Merry,
AU  - S.
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.CD012488.pub2
L1  - internal-pdf://0925341361/Thabrew-2018-Psychological therapies for anxie.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological therapies for anxiety and depression in children and adolescents with long‐term physical conditions
ER  -
TY  - JOUR
AB  - **Background: **
It is presumed that pharmacological and non-pharmacological treatment of prenatal common mental disorders can mitigate associated adverse effects in offspring, yet strong evidence for the prophylactic benefits of treatment is lacking. We therefore examined the effect of prenatal treatments for common mental disorders on offspring outcomes.

**Method(s): **
For this meta-analysis, articles published up to August 31, 2017, were obtained from PubMed, PsycInfo, Embase, and Cochrane databases. Included studies needed to be randomized controlled trials (RCTs) on the effect of treatment of prenatal common mental disorders comparing an intervention to a control condition, including offspring outcome(s). Random effects models were used to calculate Hedges&#039; g in the program Comprehensive Meta-Analysis&lt;sup&gt;&copy;&lt;/sup&gt; (version 3.0). 

**Result(s): **
Sixteen randomized controlled trials among 2778 pregnant women compared offspring outcomes between prenatal interventions and control groups. There were zero pharmacological, 13 psychological, and three other interventions (homeopathy, relaxation interventions, and short psycho-education). Birth weight (mean difference 42.88 g, g = 0.08, 95% CI -0.06 to 0.22, p = 0.27, n = 11), Apgar scores (g = 0.13, 95% CI -0.28 to 0.54, p = 0.53, n = 4), and gestational age (g = 0.03, 95% CI -0.06 to 0.54, p = 0.49, n = 10) were not significantly affected. Other offspring outcomes could not be meta-analyzed due to the inconsistent reporting of offspring outcomes and an insufficient number of studies.

**Conclusion(s): **
Non-pharmacological interventions had no significant effect on birth outcomes, although this outcome should be considered with caution due to the risk of biases. No randomized controlled trial examined the effects of prenatal pharmacological treatments as compared to treatment as usual for common mental disorders on offspring outcomes. Present clinical guidelines may require more research evidence on offspring outcomes, including child development, in order to warrant the current recommendation to routinely screen and subsequently treat prenatal common mental disorders. 

**Trial registration: **
PROSPERO CRD42016047190. 

Copyright &copy; 2018 The Author(s).
AN  - 624898749
AU  - Brouwer,
AU  - M.
AU  - E.
AU  - Williams,
AU  - A.
AU  - D.
AU  - Van
AU  - Grinsven,
AU  - S.
AU  - E.
AU  - Cuijpers,
AU  - P.
AU  - Lambregtse-Van
AU  - Den
AU  - Berg,
AU  - M.
AU  - P.
AU  - Burger,
AU  - H.
AU  - Bockting,
AU  - C.
AU  - L.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s12916-018-1192-6
L1  - internal-pdf://0943724786/Brouwer-2018-Offspring outcomes after prenatal.pdf
PY  - 2018
T2  - BMC Medicine
TI  - Offspring outcomes after prenatal interventions for common mental disorders: A meta-analysis
UR  - http://www.biomedcentral.com/bmcmed/
UR  - https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-018-1192-6
VL  - 16 (1) (no pagination)
ER  -
TY  - JOUR
AB  - The current study investigated the effect on recidivism of treatment aimed at juveniles who have sexually offended. It also assessed the potential moderating effect of type of recidivism, and several treatment, participant and study characteristics. In total, 14 published and unpublished primary studies, making use of a comparison group and reporting on official recidivism rates, were included in a multilevel meta-analysis. This resulted in the use of 77 effect sizes, and 1726 participants. A three-level meta-analytic model was used to calculate the combined effect sizes (Cohens d) and to perform moderator analyses. Study quality was assessed with the EPHPP Quality Assessment Tool for Quantitative Studies. A moderate effect size was found (d = 0.37), indicating that the treatment groups achieved an estimated relative reduction in recidivism of 20.5% as compared to comparison groups. However, after controlling for publication bias, a significant treatment effect was no longer found. Type of recidivism did not moderate the effect of treatment, indicating that treatment groups were equally effective for all types of recidivism. Also, no moderating effects of participant or treatment characteristics were found. Regarding study characteristics, a shorter follow up time showed a trend for larger effect sizes, and the effect size calculation based on proportions yielded larger effect sizes than calculation via mean frequency of offending. Implications for future research and clinical practice are discussed.
AN  - 28540447
AU  - Ter
AU  - Beek,
AU  - E.
AU  - Spruit,
AU  - A.
AU  - Kuiper,
AU  - C.
AU  - H.
AU  - Z.
AU  - van
AU  - der
AU  - Rijken,
AU  - R.
AU  - E.
AU  - A.
AU  - Hendriks,
AU  - J.
AU  - Stams,
AU  - Gjjm
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10802-017-0308-3
L1  - internal-pdf://3530205368/Ter Beek-2018-Treatment Effect on Recidivism f.pdf
PY  - 2018
SP  - 543-556
T2  - Journal of Abnormal Child Psychology
TI  - Treatment Effect on Recidivism for Juveniles Who Have Sexually Offended: a Multilevel Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=28540447
UR  - https://link.springer.com/article/10.1007%2Fs10802-017-0308-3
VL  - 46
ER  -
TY  - JOUR
AB  - **Objective**
Rational emotive behavior therapy (REBT), introduced by Albert Ellis in the late 1950s, is one of the main pillars of cognitive-behavioral therapy. Existing reviews on REBT are overdue by 10 years or more. We aimed to summarize the effectiveness and efficacy of REBT since its beginnings and investigate the alleged mechanisms of change. 

**Method**
Systematic search identified 84 articles, out of which 68 provided data for between-group analyses and 39 for within-group analyses. 

**Results**
We found a medium effect size of REBT compared to other interventions on outcomes (d = 0.58) and on irrational beliefs (d = 0.70), at posttest. For the within-group analyses, we obtained medium effects for both outcomes (d = 0.56) and irrational beliefs (d = 0.61). Several significant moderators emerged. 

**Conclusion**
REBT is a sound psychological intervention. Directions for future studies are outlined, stemming from the limitations of existing ones.
AN  - WOS:000424645500003
AU  - David,
AU  - D.
AU  - Cotet,
AU  - C.
AU  - Matu,
AU  - S.
AU  - Mogoase,
AU  - C.
AU  - Stefan,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/jclp.22514
L1  - internal-pdf://3294952409/David-2018-50 years of rational-emotive and co.pdf
PY  - 2018
SP  - 304-318
T2  - Journal of Clinical Psychology
TI  - 50 years of rational-emotive and cognitive-behavioral therapy: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000424645500003
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836900/pdf/JCLP-74-304.pdf
VL  - 74
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
We aimed to determine the benefits/efficacy of mindfulness-based interventions (MBIs) implemented among adolescents with chronic diseases in clinical settings.

**METHODS: **
An electronic search of PubMed, CINAHL, and PsycINFO databases was conducted in November 2017 to identify studies in which mindfulness was the primary intervention delivered for adolescents with chronic diseases to improve psychological and physical health.

**RESULTS: **
Nineteen eligible studies were included in this review. Fifteen studies included adolescents with psychiatric or pain disorders, and four included adolescents with a chronic physical disorders. Psychological outcomes and pain were examined in most studies with effect sizes for MBIs ranging from small to large.

**DISCUSSION: **
MBI studies conducted in clinical settings mainly engaged adolescents with psychiatric or pain disorders. The effectiveness of MBIs on improving psychological outcomes were inconsistent. Large randomized trials are needed to examine the effectiveness of MBIs and should expand to include adolescents with chronic physical diseases.
AN  - 29941236
AU  - Abujaradeh,
AU  - H.
AU  - Safadi,
AU  - R.
AU  - Sereika,
AU  - S.
AU  - M.
AU  - Kahle,
AU  - C.
AU  - T.
AU  - Cohen,
AU  - S.
AU  - M.
DA  - Sep - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.pedhc.2018.04.001
DP  - Ovid Technologies
J2  - J Pediatr Health Care
L1  - internal-pdf://0912062091/Abujaradeh-2018-Mindfulness-Based Intervention.pdf
LA  - English
N1  - Abujaradeh, HibaSafadi, ReemaSereika, Susan MKahle, Cecilia TCohen, Susan MS0891-5245(17)30634-X
PY  - 2018
SP  - 455-472
T2  - Journal of Pediatric Health Care
TI  - Mindfulness-Based Interventions Among Adolescents With Chronic Diseases in Clinical Settings: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29941236
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29941236&amp;id=doi:10.1016%2Fj.pedhc.2018.04.001&amp;issn=0891-5245&amp;isbn=&amp;volume=32&amp;issue=5&amp;spage=455&amp;pages=455-472&amp;date=2018&amp;title=Journal+of+Pediatric+Health+Care&amp;atitle=Mindfulness-Based+Interventions+Among+Adolescents+With+Chronic+Diseases+in+Clinical+Settings%3A+A+Systematic+Review.&amp;aulast=Abujaradeh&amp;pid=%3Cauthor%3EAbujaradeh+H%3C%2Fauthor%3E%3CAN%3E29941236%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S089152451730634X/1-s2.0-S089152451730634X-main.pdf?_tid=d94f0d2e-1972-41d1-9053-a40e3df00ac5&amp;acdnat=1539256751_698e2c353aa2c1ba3764f6058f1ecfb1
VL  - 32
ER  -
TY  - JOUR
AB  - **Objective: **
Present a systematic analysis of the outcome research concerning video feedback (VF) programs. 

**Method: **
Twenty-nine studies published between 1990 and 2014 were examined. They focused on children 0-12 years old and had at least one control group. 

**Results: **
VF programs were similar in design, with interventions focusing on parental and child behavior, parental sensitivity and attachment. In 41% of the measurements, the program effects were moderate or large in favor of the intervention groups, particularly regarding maternal sensitivity and children&#039;s behavior. Components of the VF programs were also examined. Two general problems emerged: lack of transparency/specificity of many programs with respect to the components, and heterogeneity among instruments used for measurement. 

**Conclusions:**
Future research should focus on articulating intervention components and a standardized approach to measurement. This would facilitate comparisons of approaches and increase the possibility of implementing VF programs with fidelity in different professional settings.
AD  - [Balldin, Stina] Lund Univ, Sch Social Work, Box 23, S-22100 Lund, Sweden. [Fisher, Philip A.] Univ Oregon, Dept Psychol, Eugene, OR 97403 USA. [Wirtberg, Ingegerd] Lund Univ, Dept Psychol, Lund, Sweden.Balldin, S (reprint author), Lund Univ, Sch Social Work, Box 23, S-22100 Lund, Sweden.stina.balldin@soch.lu.se
AN  - WOS:000441944900003
AU  - Balldin,
AU  - S.
AU  - Fisher,
AU  - P.
AU  - A.
AU  - Wirtberg,
AU  - I.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1049731516671809
J2  - Res. Soc. Work. Pract.
KW  - video feedback
KW  - interaction
KW  - maternal sensitivity
KW  - attachment
KW  - behavior
KW  - randomized control trial
KW  - attachment-based interventions
KW  - externalizing
KW  - behavior problems
KW  - mother-infant interaction
KW  - maternal sensitivity
KW  - intellectual disabilities
KW  - parenting intervention
KW  - maltreated children
KW  - outcome evaluation
KW  - adoptive families
KW  - Social Work
L1  - internal-pdf://0679934751/Balldin-2018-Video Feedback Intervention With.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GQ7SATimes Cited: 0Cited Reference Count: 97Balldin, Stina Fisher, Philip A. Wirtberg, Ingegerd0Sage publications incThousand oaks1552-7581
PY  - 2018
SP  - 682-695
T2  - Research on Social Work Practice
TI  - Video Feedback Intervention With Children: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000441944900003
VL  - 28
ER  -
TY  - JOUR
AB  - **Background**
The first three years of a child&#039;s life are a key period of physical, physiological, cognitive and social development, and the caregiver-infant relationship in early infancy plays an important role in influencing these aspects of development. Specifically, caregiver attunement facilitates the move from coregulation to self-regulation; a parent&#039;s ability to understand their infant&#039;s behaviour as communication is a key part of this process. Early, brief interventions such as the Neonatal Behavioral Assessment Scale (NBAS) or Neonatal Behavioral Observation (NBO) system are potential methods of improving outcomes for both infant and caregiver.

**Objectives**
To assess the effects of the NBAS and NBO system for improving caregiver-infant interaction and related outcomes in caregivers and newborn babies. Secondary objectives were to determine whether the NBAS and NBO are more effective for particular groups of infants or parents, and to identify the factors associated with increased effectiveness (e.g. timing, duration, etc.).

**Search methods**
In September 2017 we searched CENTRAL, MEDLINE, Embase, PsycINFO, 12 other databases and four trials registers. We also handsearched reference lists of included studies and relevant systematic reviews, and we contacted the Brazelton Institute and searched its websites to identify any ongoing and unpublished studies.

**Selection criteria**
We included randomised controlled trials (RCTs) and quasi-RCTs that had used at least one standardised measure to assess the effects of the NBAS or NBO versus inactive control for improving outcomes for caregivers and their infants.

**Data collection and analysis**
Two reviewer authors independently assessed the records retrieved from the search. One reviewer extracted data, and a second checked them for accuracy. We presented the results for each outcome in each study as standardised mean differences (SMDs) or as risk ratios (RR) with 95% confidence intervals (CIs). When appropriate, we combined the results in a meta-analysis using standard methodological procedures expected by Cochrane. We used the GRADE approach to assess the overall quality of the body of evidence for each outcome.

**Main results**
We identified and included 16 RCTs in this review: 13 assessing the NBAS and 3 the NBO for improving outcomes in 851 randomised participants, including parents and their premature or newborn (aged 4 to 12 weeks) infants. All studies took place in the USA, and we judged all of them to be at high risk of bias.  Seven studies involving 304 participants contributed data to one meta-analysis of the impact of the NBAS or NBO for caregiver-infant interaction, and the results suggest a significant, medium-sized difference between intervention and control groups (SMD &minus;0.53, 95% CI &minus;0.90 to &minus;0.17; very low-quality evidence), with moderate heterogeneity (I2 = 51%). Subgroup analysis comparing the two types of programmes (i.e. NBAS and NBO) found a medium but non-significant effect for the NBAS (&minus;0.49, 95% CI &minus;0.99 to 0.00, 5 studies), with high levels of heterogeneity (I2 = 61%), compared with a significant, large effect size for the NBO (&minus;0.69, 95% CI &minus;1.18 to &minus;0.20, 2 studies), with no heterogeneity (I2 = 0.0%). A test for subgroup differences between the two models, however, was not significant. One study found a significant impact on the secondary outcome of caregiver knowledge (SMD &minus;1.30, 95% CI &minus;2.16 to &minus;0.44; very low-quality evidence). There was no evidence of an impact on maternal depression. We did not identify any adverse effects.

**Authors&#039; conclusions**
There is currently only very low-quality evidence for the effectiveness of the NBAS and NBO in terms of improving parent-infant interaction for mostly low-risk, first-time caregivers and their infants. Further research is underway regarding the effectiveness of the NBO and is necessary to corroborate these results.
AU  - Barlow,
AU  - J.Herath,
AU  - N.
AU  - I.
AU  - Torrance,
AU  - C.
AU  - B.Bennett,
AU  - C.Wei,
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD011754.pub2
L1  - internal-pdf://2644364032/Barlow_et_al-2018-.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - The Neonatal Behavioral Assessment Scale (NBAS) and Newborn Behavioral Observations (NBO) system for supporting caregivers and improving outcomes in caregivers and their infants
ER  -
TY  - JOUR
AB  - Insomnia is highly prevalent in children and adolescents. However, the efficacy of cognitive behavioral therapy for insomnia (CBT-i) in children and adolescents remains controversial. 

Therefore, this systematic review and meta-analysis aimed to assess the efficacy of CBT-i in children and adolescents. We conducted a search of PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, CINAHL, and PsycINFO to select primary studies evaluating CBT-i in children and adolescents that were primarily diagnosed through standardized diagnostic criteria. 

The primary outcomes of the meta-analysis included sleep onset latency (SOL), wake after sleep onset (WASO), total sleep time (TST), and sleep efficiency (SE%). Six randomized controlled trials and four open-label trials met all inclusion criteria. A total of 464 participants (ranging from 5-19 years of age) were included. 

Based on the results from sleep logs, a significant pooled effect size was observed for SOL and SE%. However, no significant pooled effect size was found for WASO or TST. Results from actigraphy were consistent with the sleep logs. A significant pooled effect size was observed for SOL and SE%, and no significant pooled effect size was found for WASO or TST. CBT-i might be effective in the treatment of children and adolescents with insomnia.
AD  - Ma, Zhong-Rui. Department of Neurology, Chengdu Fifth People&#039;s Hospital, Chengdu, China.Shi, Li-Jun. Department of Hematology, Chengdu Fifth People&#039;s Hospital, Chengdu, China.Deng, Ming-Hong. Department of Neurology, Chengdu Fifth People&#039;s Hospital, Chengdu, China.
AN  - 29791593
AU  - Ma,
AU  - Z.
AU  - R.
AU  - Shi,
AU  - L.
AU  - J.
AU  - Deng,
AU  - M.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1590/1414-431x20187070
DP  - Ovid Technologies
J2  - Braz J Med Biol Res
KW  - Adolescent
KW  - Child
KW  - Child, Preschool
KW  - *Cognitive Therapy/mt [Methods]
KW  - Female
KW  - Humans
KW  - Male
KW  - Randomized Controlled Trials as Topic
KW  - *Sleep Initiation and Maintenance Disorders/th [Therapy]
KW  - Treatment Outcome
KW  - Young Adult
L1  - internal-pdf://1362038081/Ma-2018-Efficacy of cognitive behavioral thera.pdf
LA  - English
M3  - Meta-Analysis
Review
N1  - Ma, Zhong-RuiShi, Li-JunDeng, Ming-HongS0100-879X2018000600616
PY  - 2018
SP  - e7070
T2  - Brazilian Journal of Medical &amp; Biological Research
TI  - Efficacy of cognitive behavioral therapy in children and adolescents with insomnia: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=29791593
UR  - http://www.scielo.br/pdf/bjmbr/v51n6/1414-431X-bjmbr-51-6-e7070.pdf
VL  - 51
ER  -
TY  - JOUR
AB  - Portable touch-screen devices have been the focus of a notable amount of intervention research involving individuals with autism. 

Additionally, popular media has widely circulated claims that such devices and academic software applications offer tremendous educational benefits. A systematic search identified 19 studies that targeted academic skills for individuals with autism. 

Most studies used the device&#039;s built-in video recording or camera function to create customized teaching materials, rather than commercially-available applications. Analysis of potential moderating variables indicated that participants&#039; age and functioning level did not influence outcomes. 

However, participant operation of the device, as opposed to operation by an instructor, produced significantly larger effect size estimates. Results are discussed in terms of recommendations for practitioners and future research. 

Copyright &copy; 2018, Springer Science+Business Media, LLC, part of Springer Nature.
AD  - (Ledbetter-Cho, O&#039;Reilly, Lim) University of Texas at Austin, Austin, TX 78712, United States (Ledbetter-Cho, Lang) Texas State University, San Marcos, TX 78666, United States (Watkins) University of Alabama, Tuscaloosa, AL 35487, United StatesK. Ledbetter-Cho, University of Texas at Austin, Austin, TX 78712, United States. E-mail: kledbetter-cho@utexas.edu
AN  - 623381477
AU  - Ledbetter-Cho,
AU  - K.
AU  - O&#039;Reilly,
AU  - M.
AU  - Lang,
AU  - R.
AU  - Watkins,
AU  - L.
AU  - Lim,
AU  - N.
DA  - 01 Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10803-018-3573-2
DP  - Ovid Technologies
KW  - Academics
KW  - asd
KW  - Autism
KW  - iPad
KW  - iPod
KW  - Portable electronic device
KW  - article
KW  - child behavior
KW  - coding
KW  - comprehension
KW  - data extraction
KW  - evidence based practice
KW  - human
KW  - priority journal
KW  - skill
KW  - systematic review
KW  - teaching
KW  - videorecording
KW  - smartphone
KW  - tablet computer
L1  - internal-pdf://2632912926/Ledbetter-Cho-2018-Meta-analysis of Tablet-Med.pdf
LA  - English
PY  - 2018
SP  - 3021-3036
T2  - Journal of Autism and Developmental Disorders
TI  - Meta-analysis of Tablet-Mediated Interventions for Teaching Academic Skills to Individuals with Autism
UR  - http://www.wkap.nl/journalhome.htm/0162-3257
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=623381477
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1007%2Fs10803-018-3573-2&amp;issn=0162-3257&amp;isbn=&amp;volume=48&amp;issue=9&amp;spage=3021&amp;pages=3021-3036&amp;date=2018&amp;title=Journal+of+Autism+and+Developmental+Disorders&amp;atitle=Meta-analysis+of+Tablet-Mediated+Interventions+for+Teaching+Academic+Skills+to+Individuals+with+Autism&amp;aulast=Ledbetter-Cho&amp;pid=%3Cauthor%3ELedbetter-Cho+K.%3C%2Fauthor%3E%3CAN%3E623381477%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10803-018-3573-2
VL  - 48
ER  -
TY  - JOUR
AB  - **Background: **
Epidemiologic studies link maternal seafood and n-3 (omega-3) polyunsaturated fatty acid (PUFA) consumption with improved childhood cognitive development; trials show mixed results. Objective: We investigated effects of n-3 PUFA supplementation on child cognitive and visual outcomes. 

**Methods: **
We systematically reviewed and meta-analyzed randomized controlled trials of n-3 PUFA supplementation in mothers or infants (age &lt;=2 y) and evaluated standardized measures of cognitive or visual development up to age 18 y. Of 6286 abstracts and 669 full-text articles, 38 trials with 53 intervention arms were included. Data were extracted independently in duplicate. Findings were pooled using random-effects meta-analysis across supplementation periods (maternal, preterm, term infant); we also explored subgroup analyses stratified by supplementation period. Heterogeneity was explored using I2, stratified analysis, and meta-regression. Cognitive development was assessed by Bayley Scales of Infant Development mental and psychomotor developmental indexes (MDI, PDI) and intelligence quotient (IQ); visual acuity was assessed by electrophysiological or behavioral measures. 

**Results: **
The 38 trials (mothers: n = 13; preterm infants: n = 7; term infants: n = 18) included 5541 participants. When we explored effects during different periods of supplementation, n-3 PUFA supplementation improved MDI in preterm infants (3.33; 95% CI: 0.72, 5.93), without statistically significant effects on PDI or IQ in different intervention period subgroups. Visual acuity [measured as the logarithm of the minimum angle of resolution (logMAR)] was improved by supplementation in preterm (-0.08 logMAR; 95% CI: -0.14, -0.01 logMAR) and term infants (-0.08 logMAR; 95% CI: -0.11, -0.05 logMAR), with a nonsignificant trend for maternal supplementation (-0.02 logMAR; 95% CI: -0.04, 0.00 logMAR). In main analyses pooling all supplementation periods, compared with placebo, n-3 PUFA supplementation improved MDI (n = 21 trials; 0.91; 95% CI: 0.005, 1.81; P = 0.049), PDI (n = 21 trials; 1.06 higher index; 95% CI: 0.10, 2.03; P = 0.031), and visual acuity (n = 24; -0.063 logMAR; 95% CI: -0.084, -0.041 logMAR; P &lt; 0.001) but not IQ (n = 7; 0.20; 95% CI: -1.56, 1.96, P = 0.83), although few studies assessed this endpoint. Potential publication bias was identified for MDI (Eggers P = 0.005), but not other endpoints. Significant differences in findings were not identified by world region, race, maternal education, age at outcome assessment, supplementation duration, DHA or EPA dose, DHA:AA ratio, or study quality score (P-interaction &gt; 0.05 each). 

**Conclusions: **
n-3 PUFA supplementation improves childhood psychomotor and visual development, without significant effects on global IQ later in childhood, although the latter conclusion is based on fewer studies.
AN  - 29546296
AU  - Shulkin,
AU  - M.
AU  - Pimpin,
AU  - L.
AU  - Bellinger,
AU  - D.
AU  - Kranz,
AU  - S.
AU  - Fawzi,
AU  - W.
AU  - Duggan,
AU  - C.
AU  - Mozaffarian,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1093/jn/nxx031
L1  - internal-pdf://0784264702/Shulkin-2018-n-3 Fatty Acid Supplementation in.pdf
PY  - 2018
SP  - 409-418
T2  - Journal of Nutrition
TI  - n-3 Fatty Acid Supplementation in Mothers, Preterm Infants, and Term Infants and Childhood Psychomotor and Visual Development: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29546296
UR  - https://academic.oup.com/jn/article-abstract/148/3/409/4930799?redirectedFrom=fulltext
UR  - https://watermark.silverchair.com/nxx031.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAbUwggGxBgkqhkiG9w0BBwagggGiMIIBngIBADCCAZcGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMeCbhNilJJm_Hr-8qAgEQgIIBaC-xZCh2Dj8vjSUp5jZigNp80DyBbhGdu-zL9RFErdi_tlUKDwmTli9CH13HzZGjvgW92ELyUqatmiVh-WjFcE0VsqXZIfi3SfXKZUqiUV7CR144Zn1MJjbPAZyJuDNeL1CK-iL3QVvy-4j8tiqeCBRCnWrDgHi0582dfZocsU0eIPad4-LXQptjVy0or0s8KXnZsVMZsf6GoLsYFzldIiUUZo_hHY_nxiZWVIvpzEEM8OaM7UjkYZLmku0LbbH7RmDi0yxYVhRLM3dPj76J-PkJ0ID4l2QN5VqyqndNtAXWPiEqds5p2mSv4PprwKEtFzvqZ5GTTz3usnJFXrTDGhMlR49p4TPIGq1N4VSbcx3pzATVLyGJ0e76HYR1u7K5onJFeuPw88Jkn5lo0VnHBZQWOooCuS45NU-YI8zqYTRbfRwxonbL1a9AnMVY7YxVoiok8gjQpeTyj88urPiCXzuuT4HqfCxBsA
VL  - 148
ER  -
TY  - JOUR
AB  - **Background: **
Dental treatment can cause symptoms such as fear and anxiety. Audiovisual distraction (AD) is a simple and low-cost technique that does not interfere with the dental treatment.

**Aim: **
The aim of this study was to perform a systematic review and meta-analysis to evaluate the effectiveness of AD methods for children who experience anxiety during dental treatment.

**Materials and Methods:** 
Two reviewers performed a database search of the studies published between January 1950 and November 2015. The inclusion criteria were papers published in the English language, child samples aged 4-10 years, and use of AD. All potentially relevant studies were identified by the title and the abstract. After the full-text analysis of the potentially relevant studies, the selected studies were included in the systematic review. A meta-analysis calculation was performed for the overall data and the subgroup data.

**Results: **
Thirty-seven nonduplicated studies were found. However, after reviewing the articles, only five were included. A high variability was observed among the papers. Tools and questionnaires used to measure the anxiety during dental treatment presented the most common variability. Meta-analysis demonstrated a lower anxiety level in AD method groups when Modified Child Dental Anxiety Scale was used (P = 0.02) with a mean difference (confidence interval) of -8.72 (-16.7, -1.38).

**Conclusion: **
The AD method is effective for controlling dental anxiety in children.
AD  - Barreiros, Driely. Department of Pediatric Dentistry, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil.de Oliveira, Daniela Silva Barroso. Department of Pediatric Dentistry, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil.de Queiroz, Alexandra Mussolino. Department of Pediatric Dentistry, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil.da Silva, Raquel Assed Bezerra. Department of Pediatric Dentistry, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil.de Paula-Silva, Francisco Wanderley Garcia. Department of Pediatric Dentistry, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil.Kuchler, Erika Calvano. Department of Pediatric Dentistry, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, Brazil.
AN  - 29607831
AU  - Barreiros,
AU  - D.
AU  - de
AU  - Oliveira,
AU  - D.
AU  - S.
AU  - B.
AU  - de
AU  - Queiroz,
AU  - A.
AU  - M.
AU  - da
AU  - Silva,
AU  - R.
AU  - A.
AU  - B.
AU  - de
AU  - Paula-Silva,
AU  - F.
AU  - W.
AU  - G.
AU  - Kuchler,
AU  - E.
AU  - C.
DA  - Jan-Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4103/JISPPD.JISPPD_188_16
DP  - Ovid Technologies
J2  - J Indian Soc Pedod Prev Dent
LA  - English
M3  - Review
N1  - Barreiros, Drielyde Oliveira, Daniela Silva Barrosode Queiroz, Alexandra Mussolinoda Silva, Raquel Assed Bezerrade Paula-Silva, Francisco Wanderley GarciaKuchler, Erika Calvano
PY  - 2018
SP  - 2-8
T2  - Journal of the Indian Society of Pedodontics &amp; Preventive Dentistry
TI  - Audiovisual distraction methods for anxiety in children during dental treatment: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29607831
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29607831&amp;id=doi:10.4103%2FJISPPD.JISPPD_188_16&amp;issn=0970-4388&amp;isbn=&amp;volume=36&amp;issue=1&amp;spage=2&amp;pages=2-8&amp;date=2018&amp;title=Journal+of+the+Indian+Society+of+Pedodontics+%26+Preventive+Dentistry&amp;atitle=Audiovisual+distraction+methods+for+anxiety+in+children+during+dental+treatment%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Barreiros&amp;pid=%3Cauthor%3EBarreiros+D%3C%2Fauthor%3E%3CAN%3E29607831%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 36
ER  -
TY  - JOUR
AB  - The aim of this systematic review and meta-analysis was to examine the effectiveness of Stepping Stones Triple P (SSTP) parent training programs on child behavior problems and parenting outcomes in families of children with developmental disabilities. 

Sixteen suitable studies including data from over 900 families were identified in a search for English language published and unpublished controlled outcome studies. SSTP has five levels on a graded continuum of increasing intensity targeting families with differing degrees of treatment need from low intensity media-based parenting information campaigns at level 1, through brief interventions at levels 2 and 3, to more intensive parent training and family therapy interventions at levels 4 and 5. 

Analyses were conducted on the combination of all levels of SSTP and separately for each level. For combined levels, significant overall effect sizes were found for parent-reported child problems (d = 0.46), researcher observed child behavior (d = 0.51), parenting style (d = 0.70), parenting satisfaction/self-efficacy (d = 0.44), parental adjustment (d = 0.27), and coparental relationship (d = 0.26), but not researcher-observed parent behavior. 

Strong support was found for level 4 SSTP as an effective intervention for improving child and parent outcomes in families of children with disabilities who have clinically significant problems. Less intensive SSTP interventions for cases with circumscribed difficulties yielded fewer significant treatment effects, and there were relatively few studies of such interventions.
AN  - 29520764
AU  - Ruane,
AU  - A.
AU  - Carr,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/famp.12352
L1  - internal-pdf://0180351478/Ruane-2018-Systematic Review and Meta-analysis.pdf
PY  - 2018
SP  - 09
T2  - Family Process
TI  - Systematic Review and Meta-analysis of Stepping Stones Triple P for Parents of Children with Disabilities
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29520764
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1111/famp.12352
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/famp.12352
VL  - 09
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The effects of parent-based interventions on adolescent alcohol use are unclear, including what factors moderate intervention effects. This study examines the effects of parent-based interventions on adolescent alcohol use and whether the treatment effects vary by participants&#039; characteristics and intervention characteristics.

**METHODS: **
Eleven electronic databases and relevant studies&#039; references were searched for eligible studies published before March 2017. Randomized controlled trials investigating the efficacy of any parent-based intervention for alcohol use outcomes among adolescents up to 18 years old were eligible for review. Two reviewers independently conducted screening, data extraction, and risk of bias assessment. Robust variance estimation in meta-regression was used to analyze treatment effect size estimates and to conduct moderator analysis.

**RESULTS: **
Twenty studies were included in the meta-analysis. The average treatment effect size across all drinking outcomes, with 44 effect sizes from 20 studies, was g=-0.23 with a 95% confidence interval [-0.35, -0.10] which is statistically significant. Parent-based interventions appreared to have larger mean effect sizes on adolescent drinking intention than binge drinking. Interventions targeting both general and alcohol-specific parenting strategies had larger average effect sizes than interventions targeting alcohol-specific parenting only.

**CONCLUSIONS: **
This meta-analysis found evidence of parent-based interventions&#039; efficacy in preventing or reducing adolescent alcohol use.
AD  - Bo, Ai. Silver School of Social Work, New York University, 1 Washington Square North, New York, NY 10003, USA. Electronic address: ab4754@nyu.edu.Hai, Audrey Hang. Steve Hicks School of Social Work, The University of Texas at Austin, 1925 San Jacinto Blvd Doctoral Student Office, Austin, TX 78712, USA. Electronic address: audreyhai@utexas.edu.Jaccard, James. Silver School of Social Work, New York University, 1 Washington Square North, New York, NY 10003, USA. Electronic address: jj76@nyu.edu.
AN  - 30096640
AU  - Bo,
AU  - A.
AU  - Hai,
AU  - A.
AU  - H.
AU  - Jaccard,
AU  - J.
DA  - 10 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.drugalcdep.2018.05.031
DP  - Ovid Technologies
J2  - Drug Alcohol Depend
L1  - internal-pdf://2338717072/Bo-2018-Parent-based interventions on adolesce.pdf
LA  - English
M3  - Review
N1  - Bo, AiHai, Audrey HangJaccard, JamesS0376-8716(18)30365-X
PY  - 2018
SP  - 98-109
T2  - Drug &amp; Alcohol Dependence
TI  - Parent-based interventions on adolescent alcohol use outcomes: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30096640
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30096640&amp;id=doi:10.1016%2Fj.drugalcdep.2018.05.031&amp;issn=0376-8716&amp;isbn=&amp;volume=191&amp;issue=&amp;spage=98&amp;pages=98-109&amp;date=2018&amp;title=Drug+%26+Alcohol+Dependence&amp;atitle=Parent-based+interventions+on+adolescent+alcohol+use+outcomes%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Bo&amp;pid=%3Cauthor%3EBo+A%3C%2Fauthor%3E%3CAN%3E30096640%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S037687161830365X/1-s2.0-S037687161830365X-main.pdf?_tid=c867dfda-26f7-4dd8-bb81-fc1f2f7a9ef3&amp;acdnat=1539256796_0713a2794766d953a33b7597a0f2e3de
VL  - 191
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
Attention deficit hyperactivity disorder (ADHD) is a common pediatric neurobehavioral disorder often treated in the primary care setting. This systematic review updates and extends two previous Agency for Healthcare Research and Quality (AHRQ) systematic evidence reviews and focuses on the comparative effectiveness of methods to establish the diagnosis of ADHD, updates the comparative effectiveness of pharmacologic and nonpharmacologic treatments, and evaluates different monitoring strategies in the primary care setting for individuals from birth through 17 years of age. 

**DATA SOURCES: **
We searched PubMed, Embase, PsycINFO, and the Cochrane Database of Systematic Reviews for relevant English-language studies published from January 1, 2011, through November 7, 2016. 

**REVIEW METHODS: **
Two investigators screened each abstract and full-text article for inclusion, abstracted the data, and performed quality ratings and evidence grading. Random-effects models were used to compute summary estimates of effects when sufficient data were available for meta-analysis. 

**RESULTS: **
Evidence was contributed from 103 articles describing 90 unique studies. Twenty-one studies related to diagnosis, 69 studies related to treatment, and no studies were identified on monitoring. The Attention and Executive Function Rating Inventory and Childhood Executive Functioning Inventory performed better than the Cambridge Neuropsychological Test Automated Battery for the diagnosis of ADHD for ages 7-17 years (strength of evidence [SOE]=low). Evidence was insufficient on the use of electroencephalography (EEG) or neuroimaging to establish the diagnosis of ADHD for ages 7-17 years. No studies directly assessed the harms to children labeled as having ADHD. Limited additional evidence published since the original 2011 report was available on ADHD medications approved by the Food and Drug Administration (FDA) compared with placebo or compared to different FDA-approved ADHD medications (SOE=insufficient). For atomoxetine and methylphenidate, the most commonly reported adverse events were somnolence and mild gastrointestinal problems. Atomoxetine had slightly higher gastrointestinal effects than methylphenidate (SOE=low). Cognitive behavioral therapy improved ADHD symptoms (SOE=low). Child or parent training improved ADHD symptoms (SOE=moderate) but made no difference in academic performance (SOE=low). Omega-3/6 fatty acid supplementation made no difference in ADHD symptoms (SOE=moderate). Across all treatments, little evidence was reported on the risk of serious adverse events, including cardiovascular risk. 

**CONCLUSIONS: **
The 2011 AHRQ systematic review highlighted the benefit of psychostimulants for children 6-12 years of age with ADHD for up to 24 months and found that adding psychosocial/behavioral interventions to psychostimulants is more effective than psychosocial/behavioral interventions alone for children with ADHD and oppositional defiant disorder. This targeted update found insufficient evidence regarding new approaches to the diagnosis (e.g., EEGs, neuroimaging). Little is known about the impact of being labeled as having ADHD. Although cognitive behavioral therapy or child or parent training may decrease symptoms of ADHD, more information is needed regarding the relative benefit of these approaches compared to, or combined with, medication treatment. Omega-3/6 supplementation does not appear to improve ADHD outcomes. No information was identified regarding the optimal strategy for monitoring after diagnosis.
AN  - 29558081
AU  - Kemper,
AU  - A.
AU  - R.
AU  - Maslow,
AU  - G.
AU  - R.
AU  - Hill,
AU  - S.
AU  - Namdari,
AU  - B.
AU  - Allen
AU  - LaPointe,
AU  - N.
AU  - M.
AU  - Goode,
AU  - A.
AU  - P.
AU  - Coeytaux,
AU  - R.
AU  - R.
AU  - Befus,
AU  - D.
AU  - Kosinski,
AU  - A.
AU  - S.
AU  - Bowen,
AU  - S.
AU  - E.
AU  - McBroom,
AU  - A.
AU  - J.
AU  - Lallinger,
AU  - K.
AU  - R.
AU  - Sanders,
AU  - G.
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/books/NBK487761/
L1  - internal-pdf://4045337937/Kemper_2018.pdf
PY  - 2018
SP  - 01
T2  - Agency for Healthcare Research and Quality
TI  - Attention Deficit Hyperactivity Disorder: Diagnosis and Treatment in Children and Adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29558081
ER  -
TY  - JOUR
AB  - **Objective. **
To assess the effectiveness of peer inclusion in interventions to improve the social functioning of children with ADHD. 

**Methods. **
We searched four electronic databases for randomized controlled trials and controlled quasi-experimental studies that investigated peer inclusion interventions alone or combinedwith pharmacological treatment. Data were collected from the included studies and methodologically assessed. Meta-analyses were conducted using a random-effects model. 

**Results. **
Seventeen studies met eligibility criteria. Studies investigated interventions consisting of peer involvement and peer proximity; no study included peer mediation. Most included studies had an unclear or high risk of bias regarding inadequate reporting of randomization, blinding, and control for confounders. Meta-analyses indicated improvements in pre-post measures of social functioning for participants in peer-inclusive treatment groups. Peer inclusion was advantageous compared to treatment as usual. The benefits of peer inclusion over other therapies or medication only could not be determined. Using parents as raters for outcome measurement significantly mediated the intervention effect. 

**Conclusions. **
The evidence to support or contest the efficacy of peer inclusion interventions for children with ADHD is lacking. Future studies need to reduce risks of bias, use appropriate sample sizes, and provide detailed results to investigate the efficacy of peer inclusion interventions for children with ADHD.
AN  - WOS:000427673800001
AU  - Cordier,
AU  - R.
AU  - Vilaysack,
AU  - B.
AU  - Doma,
AU  - K.
AU  - Wilkes-Gillan,
AU  - S.
AU  - Speyer,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1155/2018/7693479
L1  - internal-pdf://2945513785/Cordier-2018-Peer Inclusion in Interventions f.pdf
PY  - 2018
SP  - 51
T2  - BioMed Research International
TI  - Peer Inclusion in Interventions for Children with ADHD: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000427673800001
UR  - http://downloads.hindawi.com/journals/bmri/2018/7693479.pdf
ER  -
TY  - JOUR
AB  - Literature on effects of equine therapy in individuals with autism spectrum disorder (ASD) has grown in recent times. 

Equine therapy is an alternative multimodal intervention that involves utilizing a horse to remediate core impairments in ASD. 

Recent systematic reviews in this area have several limitations including inclusion of populations other than ASD, assessment of a variety of animal-assisted interventions other than equine therapy, and a failure to conduct quantitative analyses to provide accurate effect size estimates. 

We conducted a focused systematic review to address these limitations. 

Our review suggested that equine therapy has beneficial effects on behavioral and to some extent on social communication skills in ASD. The evidence for positive effects of equine therapy on perceptuo-motor, cognitive, and functional skills is currently limited.
AD  - [Srinivasan, Sudha M.] Indian Inst Technol, IDC Sch Design, Mumbai 400076, Maharashtra, India. [Cavagnino, David T.; Bhat, Anjana N.] Univ Delaware, Dept Phys Therapy, 540 S Coll Ave, Newark, DE 19713 USA. [Bhat, Anjana N.] Univ Delaware, Dept Psychol &amp; Brain Sci, Newark, DE 19713 USA.Bhat, AN (reprint author), Univ Delaware, Dept Phys Therapy, 540 S Coll Ave, Newark, DE 19713 USA.; Bhat, AN (reprint author), Univ Delaware, Dept Psychol &amp; Brain Sci, Newark, DE 19713 USA.abhat@udel.edu
AN  - WOS:000432919200006
AU  - Srinivasan,
AU  - S.
AU  - M.
AU  - Cavagnino,
AU  - D.
AU  - T.
AU  - Bhat,
AU  - A.
AU  - N.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s40489-018-0130-z
J2  - Rev. J. Autism Dev. Disord.
KW  - Equine therapy
KW  - Hippotherapy
KW  - Therapeutic horseback riding
KW  - Social
KW  - communication
KW  - Behavior
KW  - Autism
KW  - randomized controlled-trial
KW  - assisted activities
KW  - joint attention
KW  - children
KW  - motor
KW  - adolescents
KW  - behavior
KW  - program
KW  - intervention
KW  - coordination
KW  - Psychology
L1  - internal-pdf://3678543354/Srinivasan-2018-Effects of Equine Therapy on I.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GG8AFTimes Cited: 0Cited Reference Count: 65Srinivasan, Sudha M. Cavagnino, David T. Bhat, Anjana N.Leadership Education in Neurodevelopmental and Related Disabilities (LEND) grant from the Maternal &amp; Child Health Bureau (MCHB) of the Health Resources and Service Administration (HRSA) [T73MC30116]; Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health [U54-GM104941]DC and AB&#039;s work on this manuscript was supported by the Leadership Education in Neurodevelopmental and Related Disabilities (LEND) grant from the Maternal &amp; Child Health Bureau (MCHB) of the Health Resources and Service Administration (HRSA) under grant number T73MC30116 (PI: Beth Mineo and Co-I: Brian Freedman). AB&#039;s work on this manuscript was also supported by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under grant number U54-GM104941 (PI: Binder-Macleod).0Springer heidelbergHeidelberg2195-7185
PY  - 2018
SP  - 156-175
T2  - Review Journal of Autism and Developmental Disorders
TI  - Effects of Equine Therapy on Individuals with Autism Spectrum Disorder: a Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000432919200006
UR  - https://link.springer.com/article/10.1007%2Fs40489-018-0130-z
VL  - 5
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering om effektene av programmet Zippys venner. Programmet er et universalforebyggende skolebasert tiltak for barn i første til fjerde klasse. Hovedmålet med intervensjonen er å styrke barns evne til å takle stress. Programmet gjennomføres med ukentlige økter og er basert på stress-mestringsteorier (Lazarus &amp; Folkman, 1984). Tiltaket implementeres i Norge via organisasjonen Voksne for Barn.

METODE
Denne oppsummeringen er basert på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART Cochrane, Cristin, Nora, Scopus og SweMed. To nordiske studier tilfredsstilte inklusjonskriteiene til Ungsinn og ble inkludert i oppsummeringen. Artikkelen er en revisjon av en tidligere oppsummering i Ungsinn (Bjørknes, 2013), men revidert i henhold til nye vitenskapelige kriterier for klassifisering i Ungsinn.

RESULTATER
Resultatene inkluderer en vurdering av tiltakets beskrivelse, eksisterende effektstudier, kvalitet på forskningsmetoder og implementeringskvalitet. Intervensjonen er godt beskrevet, og det fremkommer av beskrivelsen hva som er mål, målgrupper og metoder i tiltaket. Det foreligger to nordiske effektstudier. I den ene er det benyttet en kvasi-eksperimentelt design, mens det i den andre er benyttet et randomisert klyngedesign. Begge studiene inkluderer både pre-post målinger og en sammenligningsgruppe. Den ene av studiene var gjennomført med god metodisk kvalitet. Denne viste positiv effekt på elevenes mestring, og at elevene ble flinkere til aktivt å søke støtte og hjelp. Den andre studien hadde utilfredsstillende forskningsmetodisk kvalitet og resultatene fra denne studien er derfor lite pålitelige.

KONKLUSJON
Zippys venner er klassifisert på nivå 4 &ndash; Intervensjon med tilfredsstillende dokumentasjon på effekt.
AU  - Neumer,
AU  - S-P.,
AU  - Mathiassen,
AU  - B.,
AU  - Bjørknes,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2018
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Zippys venner (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/zippys-venner-2-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - Academic improvement is amongst the most common treatment targets when prescribing stimulants to children with ADHD. 

Previous reviews on stimulant-related academic improvements are inconclusive and focus on task engagement. Recent literature suggests outcome-domain-specific medication effects that are larger for productivity than for accuracy. 

The aims of this study are quantifying methylphenidate effects on academic productivity and accuracy for math, reading, spelling; exploring the mediating or moderating effects of symptom improvements, demographic-, design- and disorder-related variables. PubMed, EMBASE, ERIC and PsycINFO were searched for articles reporting methylphenidate effects on academic productivity and accuracy. 

Thirty-four studies met entry criteria. Methylphenidate improved math productivity (7.8% increase, p &lt; .001); math accuracy (3.0% increase, p = .001); increased reading speed (SMD .47, p &lt; .001) but not reading accuracy. 

None of the mediators or moderators tested affected methylphenidate efficacy. Academic improvements were small compared to symptom improvements; qualitative changes limited to math. Clinicians should take this discrepancy into account when prescribing medication for ADHD.
AN  - 29353323
AU  - Kortekaas-Rijlaarsdam,
AU  - A.
AU  - F.
AU  - Luman,
AU  - M.
AU  - Sonuga-Barke,
AU  - E.
AU  - Oosterlaan,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00787-018-1106-3
L1  - internal-pdf://0298361420/Kortekaas-Rijla-2018-Does methylphenidate impr.pdf
PY  - 2018
SP  - 20
T2  - European Child &amp; Adolescent Psychiatry
TI  - Does methylphenidate improve academic performance? A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29353323
UR  - https://link.springer.com/content/pdf/10.1007%2Fs00787-018-1106-3.pdf
VL  - 20
ER  -
TY  - JOUR
AB  - Many of the youths living in vulnerable environments in child welfare settings are in need of psychiatric treatment as well as child protection services. There is an urgent demand for closer collaboration between these two sectors in order to ensure more effective work in child welfare regarding to mental health care interventions is provided. 

The aim of this integrative review was to describe the evidence-based literature related to mental health care interventions provided in child welfare. Seven databases (PubMed, EBSCOhost, Ovid MEDLINE, Eric, CINAHL, Elsevier Science Direct, Cochrane database) were searched, while search parameters included English-only manuscripts published prior to 20 May 2016. 

Out of 152 records, only eight studies met the inclusion criteria. Mental health care interventions described varied and were listed as follows: crisis assessment, respite child care, counselling, therapeutic interviews, cognitive and educational screening, different therapies, psychoeducational support, psychological testing, behavioural assessment, individual work and brief interval care. 

Despite using comprehensive searches in seven databases, we found only eight studies related to acute psychiatric services targeted at child welfare. There is not enough evidence to arrive at a definite conclusion on the effects of mental health care interventions in child welfare.
AD  - Lahti, Mari. a Health and Well-being , Turku University of Applied Science , Turku , Finland.Lahti, Mari. b Department of Nursing Science , University of Turku , Turku , Finland.Linno, Merle. c Department of Social Sciences , University of Tarto , Tarto , Estonia.Pael, Janika. d Department of Nursing , Tartu Health Care College , Tarto , Estonia.Lenk-Adusoo, Margit. d Department of Nursing , Tartu Health Care College , Tarto , Estonia.Timonen-Kallio, Eeva. a Health and Well-being , Turku University of Applied Science , Turku , Finland.
AN  - 30153073
AU  - Lahti,
AU  - M.
AU  - Linno,
AU  - M.
AU  - Pael,
AU  - J.
AU  - Lenk-Adusoo,
AU  - M.
AU  - Timonen-Kallio,
AU  - E.
DA  - Aug 28
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/01612840.2018.1479902
DP  - Ovid Technologies
J2  - Issues Ment Health Nurs
L1  - internal-pdf://1432489858/Lahti-2018-Mental Health Care Interventions in.pdf
LA  - English
N1  - Lahti, MariLinno, MerlePael, JanikaLenk-Adusoo, MargitTimonen-Kallio, Eeva
PY  - 2018
SP  - 1-11
T2  - Issues in Mental Health Nursing
TI  - Mental Health Care Interventions in Child Welfare: Integrative Review of Evidence-Based Literature
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30153073
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30153073&amp;id=doi:10.1080%2F01612840.2018.1479902&amp;issn=0161-2840&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-11&amp;date=2018&amp;title=Issues+in+Mental+Health+Nursing&amp;atitle=Mental+Health+Care+Interventions+in+Child+Welfare%3A+Integrative+Review+of+Evidence-Based+Literature.&amp;aulast=Lahti&amp;pid=%3Cauthor%3ELahti+M%3C%2Fauthor%3E%3CAN%3E30153073%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/pdf/10.1080/01612840.2018.1479902?needAccess=true
ER  -
TY  - JOUR
AB  - **CONTEXT: **
Early childhood stimulation interventions positively impact early child development (ECD) outcomes in low- and middle-income countries. However, trials have less comprehensively evaluated the effects of such parenting programs on caregivers&#039; skills and capacities. 

**OBJECTIVE: **
We conducted a systematic review and meta-analysis to assess the effectiveness of stimulation interventions on improving parenting outcomes. 

**DATA SOURCES: **
Six electronic bibliographic databases. 

**STUDY SELECTION: **
Inclusion criteria included randomized controlled trials of stimulation interventions designed to improve ECD outcomes during the first 2 years of life that measured any maternal or parenting-related outcome after the start of the intervention. 

**DATA EXTRACTION: **
Two independent reviewers extracted data by using a structured form. 

**RESULTS: **
Fifteen studies representing 13 unique randomized controlled trials met the inclusion criteria. Pooled standardized mean differences (SMDs) based on random-effects models revealed medium-to-large benefits of stimulation interventions for improving the home caregiving environment (n = 10; SMD = 0.57; 95% confidence interval [CI], 0.37 to 0.77), mother-child interactions (n = 3; SMD = 0.44; 95% CI, 0.14 to 0.74), and maternal knowledge of ECD (n = 6; SMD = 0.91; 95% CI, 0.51 to 1.31). No significant difference was seen for maternal depressive symptoms (n = 9; SMD = -0.10; 95% CI, -0.23 to -0.03). 

**LIMITATIONS: **
Limitations include heterogeneity across interventions, lack of standardized measures, and different time points of assessments across studies. 

**CONCLUSIONS: **
Early childhood stimulation interventions improve several distinct aspects of maternal parenting. Improvements in parenting capacities may serve as key mechanisms by which these programs benefit ECD outcomes.
AN  - 29500293
AU  - Jeong,
AU  - J.
AU  - Pitchik,
AU  - H.
AU  - O.
AU  - Yousafzai,
AU  - A.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1542/peds.2017-3510
L1  - internal-pdf://2116022070/Jeong-2018-Stimulation Interventions and Paren.pdf
PY  - 2018
T2  - Pediatrics
TI  - Stimulation Interventions and Parenting in Low- and Middle-Income Countries: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29500293
UR  - http://pediatrics.aappublications.org/content/141/4/e20173510?sso=1&amp;sso_redirect_count=1&amp;nfstatus=401&amp;nftoken=00000000-0000-0000-0000-000000000000&amp;nfstatusdescription=ERROR%3a+No+local+token
UR  - http://pediatrics.aappublications.org/content/pediatrics/141/4/e20173510.full.pdf
VL  - 141
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To synthesize the results of controlled studies evaluating the effectiveness of animal-assisted therapy (AAT) in children.

**METHODS: **
Eleven databases were searched following the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement recommendations, and references from included studies and previous reviews were examined. No date or language filters were applied. Only controlled study designs, including those using wait-list controls, that studied a specific condition or illness were included. Study quality was assessed using the Cochrane Risk of Bias Tool.

**RESULTS: **
Twenty-six studies that met the inclusion criteria were retrieved. Nine were conducted in children with autism spectrum disorders, 10 in cerebral palsy (CP), 2 in Down syndrome, 3 in pain, and 2 in other conditions. Qualitative synthesis showed a small but significant contribution of AAT to the management of these conditions. Meta-analysis showed a mean difference in improvement in the Gross Motor Function Measure-66 scale in children with CP of 1.61 (95% confidence interval [CI] -2.00 to 5.23) and a mean difference for 5-point pain scales of -0.81 (95% CI -1.32 to 0.30), both favoring AAT.

**CONCLUSION: **
Animal-assisted therapy may be useful as a complementary intervention in the management of children with CP and pain. Although results are in general positive for the management of children with Down syndrome and autism, the diversity of scales used to measure outcomes makes it difficult to establish true effectiveness. The application of simple corrective measures in the randomization process would greatly improve the quality of evidence. It is necessary to reach a consensus between AAT researchers regarding appropriate instruments to provide higher-quality evidence in further studies.
AD  - Charry-Sanchez, Jesus David. Neuroscience Undergraduate Research Group (NeURos), Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogota DC, Colombia.Pradilla, Ivan. Neuroscience Unit, Neuroscience Research Group (NeURos), Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogota DC, Colombia.Talero-Gutierrez, Claudia. Neuroscience Unit, Neuroscience Research Group (NeURos), Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogota DC, Colombia.
AN  - 29994814
AU  - Charry-Sanchez,
AU  - J.
AU  - D.
AU  - Pradilla,
AU  - I.
AU  - Talero-Gutierrez,
AU  - C.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/DBP.0000000000000594
DP  - Ovid Technologies
J2  - J Dev Behav Pediatr
L1  - internal-pdf://3917480171/Charry-Sanchez-2018-Effectiveness of Animal-As.pdf
LA  - English
N1  - Charry-Sanchez, Jesus DavidPradilla, IvanTalero-Gutierrez, Claudia
PY  - 2018
SP  - 580-590
T2  - Journal of Developmental &amp; Behavioral Pediatrics
TI  - Effectiveness of Animal-Assisted Therapy in the Pediatric Population: Systematic Review and Meta-Analysis of Controlled Studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29994814
VL  - 39
ER  -
TY  - JOUR
AB  - **Background:** 
Young people require specific attention when it comes to suicide prevention, however efforts need to be based on robust evidence. 

**Methods:** 
We conducted a systematic review and meta-analysis of all studies examining the impact of interventions that were specifically designed to reduce suicide-related behavior in young people. 

**Findings:** 
Ninety-nine studies were identified, of which 52 were conducted in clinical settings, 31 in educational or workplace settings, and 15 in community settings. Around half were randomized controlled trials. Large scale interventions delivered in both clinical and educational settings appear to reduce self-harm and suicidal ideation post-intervention, and to a lesser extent at follow-up. In community settings, multi-faceted, place-based approaches seem to have an impact. Study quality was limited. 

**Interpretation:** 
Overall whilst the number and range of studies is encouraging, gaps exist. Few studies were conducted in low-middle income countries or with demographic populations known to be at increased risk. Similarly, there was a lack of studies conducted in primary care, universities and workplaces. However, we identified that specific youth suicide-prevention interventions can reduce self-harm and suicidal ideation; these types of intervention need testing in high-quality studies.
AN  - 31193651
AU  - Robinson,
AU  - J.
AU  - Bailey,
AU  - E.
AU  - Witt,
AU  - K.
AU  - Stefanac,
AU  - N.
AU  - Milner,
AU  - A.
AU  - Currier,
AU  - D.
AU  - Pirkis,
AU  - J.
AU  - Condron,
AU  - P.
AU  - Hetrick,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.eclinm.2018.10.004
L1  - internal-pdf://1431610764/Robinson-2018-What Works in Youth Suicide Prev.pdf
PY  - 2018
SP  - 52-91
TI  - What Works in Youth Suicide Prevention? A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=31193651
UR  - https://pdf.sciencedirectassets.com/319402/1-s2.0-S2589537018X00042/1-s2.0-S2589537018300415/main.pdf?X-Amz-Security-Token=AgoJb3JpZ2luX2VjECcaCXVzLWVhc3QtMSJIMEYCIQDKQCDsk%2FaQa3vWgd5WeOEVVgHdMOTa3s4SO2z7J1WnKQIhAK0s%2BvYSjW9%2BFZwow0ZeJBxCAEXNRCsb9emk7z%2FZ%2FX3GKuMDCKD%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEQAhoMMDU5MDAzNTQ2ODY1Igy8OlkbbDwW0pTBJKgqtwO7pbzo%2Brlmc%2B%2FHRSTe2WkIi1qLtL62vPdI0cXmBjz85h%2FtLgddvVHl1tBIf9kFM0RYwT7DfopgNiDpe7kjlMBizlvd3DgKvXCrz4LApp8JvCa1T15Hs%2BZLlnvMbFR4HxbjPbw94UHpX%2BS2JhFyULZvEGTHf4ZRSi93EP39wf61QjKrhx8WxUnsVnz3BuRemPY5bjGRFQZkowApOGuBGC3zKysbA5nGIziAzlfnaqJ5vHC6yYpzZoAzvP%2FvB%2F%2F3CFd%2Bx%2FwXkqdLZdoLlA%2Fd9g4L9ep851BnAg09alfVYnxJ2XZhATf12NdCwWwiP%2FAPwHRZ%2BA%2BUQFITYrjW9UmvIGjR9Av%2FxoIPIW3taeTcC7cLXI%2FN0sTJXe5GqT%2BF%2FiirRPQZNGnnorr3MInKiUtC1nAcrX1yD5q%2BRkE%2FFWACuk2JWgwa%2FQsAP2wXOkgbz3Ypl9nlZSuF51CSd6yBkqDmXQ76%2BZlDONOro4zH9nIIFOfKLF9S6U2rkI77Gx4szI0sro64S%2FPwudLRmqAyChhSK8K%2BM8IoSli%2FQGSdUNTWPY9aQ26p1EGEqdkoLRIakEmJ5GnhlE%2FEx%2BPaMKnshOoFOrMBg9s7qHSNdIYS2S0Ol3jltoeHcvOBI5pJe1X%2F5umV8NyNcOjcVXulEnDzK%2BcCA6280ps2Q6sAO0IRme20OA%2FGEZAdmy4XNVw9hxMJjeEvuXbV8lfa3uYIsek62i3eEd2%2B5wZiam1elLlCDdkIUL9JwQhs9F0N%2FJb5XUnzCf%2B8S8Q5wSJu%2FLAIQKwobtzMX1MMTxuSW8XD2kkQhM9l2xkQR%2BT55%2BqNnYHFFtpWIBJz2pkq1Mg%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20190731T075949Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTYUMFSSDGB%2F20190731%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=e0c6ba4bcce57a66cef6b481dbd162f4ce00d9bc590db5650bdfeddd4d84e781&amp;hash=99e6d4af379cb6ca630b8a5513f24ab2a16114f11dc6075e485a93b060357012&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S2589537018300415&amp;tid=spdf-551ee4d8-627c-437a-96aa-b3e24433feb6&amp;sid=5239e28b53c4514899390fe5a74f9e378139gxrqb&amp;type=client
VL  - 4-5
ER  -
TY  - JOUR
AB  - **Background: **
Cannabis use in adolescence is associated with multiple psychosocial problems. Barriers to care limit access to evidence based interventions. Electronic devices can facilitate access to interventions designed to reduce cannabis use. 

**Objective(s): **
We conducted a systematic review of randomized trials employing electronically delivered interventions to assess for feasibility and effectiveness of this modality in reducing cannabis use among adolescents and young adults. 

**Method(s): **
Major databases were searched for randomized trials using electronically delivered interventions (web-based + tablets, computers or CD-ROM) for cannabis use in adolescents and young adults published before July 2016. The outcome measure was decrease in cannabis use frequency. We conducted a quality assessment of these studies and qualitatively synthesized study findings. 

**Result(s): **
Thirteen articles representing eleven studies were included in this systematic review. Seven studies were effective in reducing cannabis use with small to medium effect sizes (0.07 to 0.66). Studies with significant reduction in cannabis use were likely to be a universal or selective intervention (100% [U], 80% [S)] vs 25% for indicated programs), target early adolescence (100% vs 33% for middle or late adolescence), employ family interaction theory (100% vs [33 -67%] for other theories) and have greater than 6 sessions (100% vs 33% for shorter sessions). 

**Conclusion(s):**
Our findings indicate that electronically-delivered interventions aimed at reducing cannabis use are feasible in youth, and can be effective. Certain factors, such as age at delivery, underlying theory, and number of sessions appear to play a role in the effectiveness of this mode of delivery. Further studies are needed to confirm these findings. 

Copyright &copy; 2018 Bentham Science Publishers.
AN  - 2001856012
AU  - Asuzu,
AU  - K.
AU  - Matin,
AU  - A.
AU  - Van
AU  - Noord,
AU  - M.
AU  - Onigu-Otite,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2174/2210676609666181203094249
L1  - internal-pdf://4014968102/Asuzu-2018-Electronically-delivered interventi.pdf
PY  - 2018
SP  - 195-213
T2  - Adolescent Psychiatry
TI  - Electronically-delivered interventions to reduce cannabis use in adolescents: A systematic review
UR  - http://www.eurekaselect.com/167973/article
VL  - 8
ER  -
TY  - JOUR
AB  - The purpose of this systematic review is to summarize the effects of interagency and cross-system collaboration aimed to improve child welfare-involved children and family outcomes related to safety, permanency, and well-being. 

We conducted a comprehensive search to identify studies that evaluated interagency/cross-system child welfare collaborations, resulting in 11 studies selected for inclusion. The analysis included narrative and meta-analysis approaches. All selected studies focused on substance use; our search criteria did not identify any interagency collaborations related to other co-occurring conditions, such as domestic violence and mental health. 

Results from both narrative and meta-analyses revealed family drug treatment court (FDTC) collaboration intervention was positively associated with the entry (OR = 2.935, 95% CI [1.498, 5.753]) and completion (OR = 2.074, 95% CI [1.263, 3.406]) of substance use services. Additionally, FDTC (OR = 2.401, 95% CI [1.751, 3.292]) and recovery coaches (OR = 1.522, 95% CI [1.166, 1.987]) were positively associated with likelihood of reunification. 

Narrative and meta-analysis results related to the relationship between FDTC and days to reunification were less positive across studies (g = 0.470, 95% CI [0.247, 0.694]). Thus suggesting, although FDTC may positively influence the likelihood that children are reunified with their families in the future, this intervention may have less influence on how quickly families achieve the reunification process. 

We found positive client outcomes regardless if there existed a lower (co-ordination) or higher (integration) level of collaboration, demonstrating positive collaboration outcomes may occur using limited child welfare resources. This systematic review can benefit child welfare practitioners, policymakers, and families in selecting the most appropriate and effective interagency/cross-system substance use services. We discuss recommendations for future research. 

(PsycINFO Database Record (c) 2018 APA, all rights reserved)
AN  - 2018-56761-029
AU  - Ogbonnaya,
AU  - I.
AU  - N.
AU  - Keeney,
AU  - A.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2018.10.008
L1  - internal-pdf://4099997442/Ogbonnaya-2018-A systematic review of the effe.pdf
PY  - 2018
SP  - 225-245
T2  - Children and Youth Services Review
TI  - A systematic review of the effectiveness of interagency and cross-system collaborations in the United States to improve child welfare outcomes
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2018-56761-029
UR  - https://ac.els-cdn.com/S0190740918304997/1-s2.0-S0190740918304997-main.pdf?_tid=3ab1fc31-6caa-46f2-97a1-c0b984841a26&amp;acdnat=1547554324_43d0ce198fd09b97bcbdc96f51f863f0
VL  - 94
ER  -
TY  - JOUR
AB  - **Study Objectives: **
Sleep problems are common in children and adolescents and can aggravate comorbid disorders. This meta-analysis examined the effect of cognitive and behavioral sleep interventions (with four or more treatment sessions) from randomized controlled trials on school-age children and adolescents. 

**Method(s): **
In a systematic literature search, six randomized controlled trials were identified (n = 528; mean age = 14.6 years; female = 63%) that reported total sleep time (TST), sleep onset latency (SOL), wake after sleep onset, and daytime sleepiness from ratings and actigraphy. 

**Result(s): **
After intervention, no effect was seen on self-reported TST, but when measured with actigraphy, an effect favoring the intervention group was observed (+11.47 minutes, P = .05). SOL decreased in the intervention group compared to the control group after intervention as measured by both sleep diaries (-9.31 minutes, P = .007) and actigraphy (-19.48 minutes, P &lt; .0001). Effect sizes ranged from small to large. No effect was found for wake after sleep onset or daytime sleepiness. Short-term (4 to 8 weeks) follow-up data from four studies indicated maintained positive effects on SOL: sleep diaries -15.85 minutes (P = .01) and actigraphy -23.67 minutes (P &lt; .0001). At follow-up, the effects on wake after sleep onset from ratings (-14.41 minutes, P = .001) and actigraphy (-7.54 minutes, P = .01) were significant, favoring the intervention group (moderate to large effect sizes). No effect on TST was indicated. 

**Conclusion(s): **
Cognitive and behavioral sleep interventions are indicated to improve sleep in school-age children and adolescents. However, because treatment protocols were heterogeneous and risk of bias high, results should be interpreted with caution. Large and rigorous trials are needed. 

Copyright &copy; 2018 American Academy of Sleep Medicine. All rights reserved.
AN  - 624998373
AU  - Aslund,
AU  - L.
AU  - Arnberg,
AU  - F.
AU  - Kanstrup,
AU  - M.
AU  - Lekander,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.5664/jcsm.7498
L1  - internal-pdf://3245478725/Aslund-2018-Cognitive and behavioral intervent.pdf
PY  - 2018
SP  - 1937-1947
T2  - Journal of Clinical Sleep Medicine
TI  - Cognitive and behavioral interventions to improve sleep in school-age children and adolescents: A systematic review and meta-analysis
UR  - http://jcsm.aasm.org/ViewAbstract.aspx?pid=31442
VL  - 14
ER  -
TY  - JOUR
AB  - **Importance:** 
Anxiety disorders are common in children and adolescents, and uncertainty remains regarding the optimal strategy of psychotherapies in this population.

**Objective:** 
To compare and rank the different types of psychotherapies and the different ways of delivering psychological treatments for anxiety disorders in children and adolescents.

**Data Sources:** 
PubMed, Cochrane Central Register of Controlled Trials, EMBASE, PsycINFO, Web of Science, CINAHL (Cumulative Index to Nursing and Allied Health Literature), ProQuest Dissertations, LILACS (Literatura Latino Americana em Ciencias da Saude), international trial registers, and US Food and Drug Administration reports were searched from inception to November 30, 2017.

**Study Selection:** 
Randomized clinical trials that compared any structured psychotherapy with another psychotherapy or a control condition for anxiety disorders in children and adolescents were selected.

**Data Extraction and Synthesis:** 
Four researchers independently performed data extraction and quality assessment. Pairwise meta-analyses and Bayesian network meta-analysis within the random-effects model were used to synthesize data.

**Main Outcomes and Measures:** 
Efficacy (change in anxiety symptoms) posttreatment and at follow-up, acceptability (all-cause discontinuation), and quality of life and functional improvement were measured. The certainty of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation framework.

**Results:** 
A total of 101 unique trials including 6625 unique participants compared 11 different psychotherapies with 4 specific control conditions. The certainty of evidence was rated as low or very low for most comparisons. For efficacy, most psychotherapies were significantly more effective than the wait list condition posttreatment (standardized mean difference [SMD], -1.43 to -0.61) and at the longest follow-up (SMD, -1.84 to -1.64). However, only group cognitive behavioral therapy (CBT) was significantly more effective than the other psychotherapies and all control conditions posttreatment. For acceptability, bibliotherapy CBT had significantly more all-cause discontinuations than some psychotherapies and control conditions (range of odds ratios, 2.48-9.32). In terms of quality of life and functional improvement, CBT (delivered in different ways) was significantly beneficial compared with psychological placebo and the wait list condition (SMDs, 0.73 to 1.99).

**Conclusions and Relevance:** 
Group CBT would be the more appropriate choice of psychotherapy for anxiety disorders in children and adolescents, based on these findings. Other types of psychotherapies and different ways of delivering psychological treatment can be alternative options. Further research is needed to explore specific anxiety disorders, disorder-specific psychotherapy, and moderators of treatment effect.Trial Registration: PROSPERO Identifier: CRD42015016283.
AD  - Zhou, Xinyu. Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Zhang, Yuqing. Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.Zhang, Yuqing. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Furukawa, Toshiaki A. Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine/School of Public Health, Kyoto, Japan.Cuijpers, Pim. Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.Pu, Juncai. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Weisz, John R. Department of Psychology, Harvard University, Cambridge, Massachusetts.Yang, Lining. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Hetrick, Sarah E. Department of Psychological Medicine, University of Auckland, Auckland, New Zealand.Hetrick, Sarah E. Centre of Youth Mental Health, University of Melbourne, Melbourne, Australia.Del Giovane, Cinzia. Institute of Primary Health Care, University of Bern, Bern, Switzerland.Cohen, David. Department of Child and Adolescent Psychiatry, Hopital Pitie-Salpetriere, Institut des Systemes Intelligents et Robotiques, Universite Pierre et Marie Curie, Paris, France.James, Anthony C. Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom.James, Anthony C. Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, United Kingdom.Yuan, Shuai. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Whittington, Craig. Doctor Evidence, Santa Monica, California.Jiang, Xiaofeng. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Teng, Teng. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.Cipriani, Andrea. Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom.Cipriani, Andrea. Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, United Kingdom.Xie, Peng. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
AN  - 30383099
AU  - Zhou,
AU  - X.
AU  - Zhang,
AU  - Y.
AU  - Furukawa,
AU  - T.
AU  - A.
AU  - Cuijpers,
AU  - P.
AU  - Pu,
AU  - J.
AU  - Weisz,
AU  - J.
AU  - R.
AU  - Yang,
AU  - L.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Del
AU  - Giovane,
AU  - C.
AU  - Cohen,
AU  - D.
AU  - James,
AU  - A.
AU  - C.
AU  - Yuan,
AU  - S.
AU  - Whittington,
AU  - C.
AU  - Jiang,
AU  - X.
AU  - Teng,
AU  - T.
AU  - Cipriani,
AU  - A.
AU  - Xie,
AU  - P.
DA  - Oct 31
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1001/jamapsychiatry.2018.3070
DP  - Ovid Technologies
J2  - JAMA Psychiatry
L1  - internal-pdf://3691025313/Zhou-2018-Different Types and Acceptability of.pdf
LA  - English
N1  - Using Smart Source ParsingOctZhou, XinyuZhang, YuqingFurukawa, Toshiaki ACuijpers, PimPu, JuncaiWeisz, John RYang, LiningHetrick, Sarah EDel Giovane, CinziaCohen, DavidJames, Anthony CYuan, ShuaiWhittington, CraigJiang, XiaofengTeng, TengCipriani, AndreaXie, Peng
PY  - 2018
SP  - 41-50
T2  - JAMA Psychiatry
TI  - Different Types and Acceptability of Psychotherapies for Acute Anxiety Disorders in Children and Adolescents: A Network Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30383099
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30383099&amp;id=doi:10.1001%2Fjamapsychiatry.2018.3070&amp;issn=2168-622X&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=JAMA+Psychiatry&amp;atitle=Different+Types+and+Acceptability+of+Psychotherapies+for+Acute+Anxiety+Disorders+in+Children+and+Adolescents%3A+A+Network+Meta-analysis.&amp;aulast=Zhou&amp;pid=%3Cauthor%3EZhou+X%3C%2Fauthor%3E%3CAN%3E30383099%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://jamanetwork.com/journals/jamapsychiatry/articlepdf/2709652/jamapsychiatry_zhou_2018_oi_180077.pdf
VL  - 76
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Although caregiver-delivered social communication interventions have been considered scientifically proven practices for individuals with autism spectrum disorders, it is not well examined if these types of intervention modes are truly effective in promoting skill generalization and maintenance within those individuals with autism spectrum disorders. 

**AIMS: **
The purpose of this meta-analysis was to evaluate the status of the extant literature regarding the measures on generalization and/or maintenance of effects of caregiver-delivered communication interventions for children with autism spectrum disorders. 

**METHODS AND PROCEDURES: **
This systematic literature review and meta-analysis evaluated peer-reviewed research regarding the effects of caregiver-implemented interventions on the maintenance and generalization of the social-communication skills for children with autism spectrum disorders. A total of 34 articles were included following a systematic search. Articles were summarized according to the following categories: (a) generalization dimension, (b) generalization assessment design, (c) maintenance assessment design, (d) generalization/maintenance teaching strategy, and (e) latency to maintenance probes. After application of design standards, aggregate Tau-U and non-overlap of pairs effect sizes were calculated with a total of 67 separate contrasts across seven studies. 

**OUTCOMES AND RESULTS: **
Overall, effect size scores ranged from small to large effects across all comparisons. On average, most of the baseline to maintenance and generalization comparisons produced moderate to large effects. Whereas, small to moderate or even deteriorate effects were found in most of the intervention to maintenance and generalization comparisons. 

**CONCLUSIONS AND IMPLICATIONS: **
The findings in this review suggest that caregiver-delivered social-communication interventions are likely to result in mixed effects on skill generalization and maintenance within children with autism spectrum disorders. Implications for future research and practice are discussed.
AN  - 29360047
AU  - Hong,
AU  - E.
AU  - R.
AU  - Neely,
AU  - L.
AU  - Gerow,
AU  - S.
AU  - Gann,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ridd.2018.01.006
L1  - internal-pdf://4161316621/Hong-2018-The effect of caregiver-delivered so.pdf
PY  - 2018
SP  - 57-71
T2  - Research in Developmental Disabilities
TI  - The effect of caregiver-delivered social-communication interventions on skill generalization and maintenance in ASD
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29360047
UR  - https://www.sciencedirect.com/science/article/pii/S089142221830012X?via%3Dihub
VL  - 74
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Weight gain is a potentially concerning side effect of second-generation antipsychotics (SGAs). Metformin, a biguanide with antihyperglycemic effects, is used to manage weight gain in adults treated with SGAs. 

**OBJECTIVE: **
The objective of this study was to perform the first systematic review and meta-analysis of randomized controlled trials (RCTs) assessing the effects of metformin on weight gain in children and adolescents treated with SGAs. 

**METHODS: **
Based on a pre-registered protocol (PROSPERO-CRD42017074839), we searched the PubMed, EMBASE, PsychoINFO, BIOSIS, Science Direct, Cochrane Central, and ClinicalTrials.gov electronic databases through March 2018 (with no restrictions on language, date, or type of publication) for RCTs that assessed the effect of metformin or placebo on body weight in children or adolescents (&lt; 18 years of age) treated with selected SGAs (risperidone, aripiprazole, olanzapine, and clozapine) for any psychiatric disorder. We also contacted relevant drug manufacturers for possible additional pertinent studies/data. A random effects model was used and the quality of the included RCTs was assessed using the Cochrane Risk of Bias tool. 

**RESULTS:**
Five RCTs (205 participants in total) were included in the meta-analysis. We found a significant weight decrease in the metformin group compared with placebo after 4, 12, and 16 weeks of treatment {mean difference - 0.98 kg (95% confidence interval [CI] - 1.26, - 0.69); - 1.83 kg (95% CI - 2.47, - 1.18); and - 3.23 kg (95% CI - 5.59, - 0.86), respectively}. A weight decrease at weeks 2 and 8 did not reach statistical significance. The decrease in body mass index (BMI) paralleled that of weight, with a significant effect at weeks 4, 12, and 16. Overall, four studies were rated as unclear, and one study was rated as high, risk of bias. 

**CONCLUSION: **
Meta-analytical evidence shows that metformin might decrease weight in children/adolescents treated with SGAs but additional high-quality evidence is needed. Clinicians need to be aware that this use of metformin is currently off-label.
AN  - 30238318
AU  - Ellul,
AU  - P.
AU  - Delorme,
AU  - R.
AU  - Cortese,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s40263-018-0571-z
L1  - internal-pdf://0651235275/Ellul-2018-Metformin for Weight Gain Associate.pdf
PY  - 2018
SP  - 1103-1112
T2  - CNS Drugs
TI  - Metformin for Weight Gain Associated with Second-Generation Antipsychotics in Children and Adolescents: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30238318
UR  - https://link.springer.com/article/10.1007%2Fs40263-018-0571-z
VL  - 32
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Existing systematic reviews provide evidence that music therapy is an effective intervention in the treatment of children and adolescents with psychopathology. The objective of the present review was to systematically review and quantify the effects of music-based interventions in reducing internalizing symptoms (i.e., depression and anxiety) in children and adolescents using a meta-analytical approach. 

**METHODS: **
Databases and journals were systematically screened for studies eligible for inclusion in meta-analysis on the effects of music-based interventions in reducing internalizing symptoms. A random-effect meta-analysis using standardized mean differences (SMD) was conducted. 

**RESULTS: **
Five studies were included. Analysis of data from (randomized) controlled trials, yielded a significant main effect (Hedge&#039;s g = -0.73; 95%CI [-1.42;-0.04], Z = 2.08, p = 0.04, k = 5), indicating a greater reduction of internalizing symptoms in youth receiving music-based interventions (n = 100) compared to different control group interventions (n = 95). 

**LIMITATIONS:**
The existing evidence is limited to studies of low power and methodological quality. Included studies were highly heterogeneous with respect to the nature of the intervention, the measurements applied, the samples studied, and the study design. 

**CONCLUSIONS: **
Findings indicate that music-based interventions may be efficient in reducing the severity of internalizing symptoms in children and adolescents. While these results are encouraging with respect to the application of music-based intervention, rigorous research is necessary to replicate existing findings and provide a broader base of evidence. More research adopting well controlled study designs of high methodological quality is needed.
AN  - 28889050
AU  - Geipel,
AU  - J.
AU  - Koenig,
AU  - J.
AU  - Hillecke,
AU  - T.
AU  - K.
AU  - Resch,
AU  - F.
AU  - Kaess,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jad.2017.08.035
L1  - internal-pdf://3160412937/Geipel-2018-Music-based interventions to reduc.pdf
PY  - 2018
SP  - 647-656
TI  - Music-based interventions to reduce internalizing symptoms in children and adolescents: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28889050
VL  - 225
ER  -
TY  - JOUR
AB  - Based on published research on the combined cognitive behavioral therapy (CBT) versus drug therapy alone in children with attention deficit/hyperactivity disorder (ADHD), we systematically reviewed and analyzed the efficacy of two treatment methods in children with ADHD. 

The literature as at the end of 10 July 2017 in multiple databases was systematically searched. Standardized mean differences (SMD) and 95% confidence intervals (CIs) were calculated.

The results indicated that combined CBT therapy was efficacious in reducing symptoms of ADHD (SDM -0.48, 95% CI -0.80 to -0.17). The executive function scores were not improved more in the combined CBT (SMD -0.34; 95% CI -0.71 to 0.03). This study suggests that combined CBT seems more efficacious in some domains affecting children with ADHD, but further evaluation is needed. Copyright &copy; 2018 Institutes of Integrative Medicine, Fudan University.
AN  - 2015915446
AU  - Ding,
AU  - Q.
AU  - Li,
AU  - M.
AU  - Zhu,
AU  - D.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1142/S2575900018400013
L1  - internal-pdf://2242713525/Ding-2018-Is combined CBT therapy more effecti.pdf
PY  - 2018
SP  - 21-26
T2  - Traditional Medicine and Modern Medicine
TI  - Is combined CBT therapy more effective than drug therapy alone for ADHD in children? A meta-analysis
UR  - https://www.worldscientific.com/worldscinet/tmmm
UR  - https://www.worldscientific.com/doi/pdf/10.1142/S2575900018400013?download=true
VL  - 1(1)
ER  -
TY  - JOUR
AB  - **PURPOSE:** 
To systematically review evidence on the benefits and harms of interventions provided in or referable from primary care to prevent child maltreatment for the U.S. Preventive Services Task Force (USPSTF). 

**DATA SOURCES:** 
MEDLINE, the Cochrane Library, EMBASE, and trial registries, through December 18, 2017; reference lists of retrieved articles; outside experts; reviewers; and surveillance of literature through July 17, 2018 

**STUDY SELECTION:** 
Two investigators independently selected studies using a priori criteria. Eligible trials (1) enrolled children (from birth through age 18 years with no known exposure to maltreatment and no signs or symptoms of current or past maltreatment) or their caregivers; (2) evaluated interventions feasible in a primary care setting or that could result from a referral by a primary care provider; and (3) reported abuse or neglect outcomes, or proxies for abuse or neglect (injury, visits to the emergency department, hospitalization). 

**DATA EXTRACTION:** 
One investigator extracted data and a second checked accuracy. Two reviewers independently rated quality for included studies using predefined criteria. 

**DATA SYNTHESIS:** 
Twenty-two trials provided evidence on benefits. We found no evidence of differences in reports to child protective services within 1 year of intervention completion (pooled odds ratio [OR], 0.94, 95% CI, 0.72 to 1.23; 10.6% vs. 11.9%; 10 studies, 2444 participants) or removal of the child from the home within 1 to 3 years of followup (pooled (OR: 1.09,95% CI, 0.16 to 7.28; 3.51% vs. 3.71%; 4 studies, 609 participants). Owing to heterogeneity of outcome measures, we could not pool other results, but the evidence either demonstrates no benefit or was inconclusive for abuse, neglect, or their sequelae. The evidence suggested no benefit for emergency department visits in the short-term (&lt;2 years), hospitalizations, child development, school performance, and prevention of death. The evidence was inconclusive for long-term outcomes for reports to child protective services and emergency department visits (&gt;=2 years) because results were inconsistent and imprecise. The evidence was also inconclusive for injuries, failure to thrive, failure to immunize, internalizing and externalizing behavior symptoms, school attendance, and other measures of abuse or neglect because of the limited number of trials reporting on each outcome and imprecise results. We found no results on harms. 

**LIMITATIONS:** 
The scope of this review limits conclusions to children who have not experienced maltreatment and to primary-care relevant interventions. Other limitations include the heterogeneity of the interventions and outcome measures and the lack of information on harms. 

**CONCLUSIONS:** 
Overall, the evidence on interventions provided in or referable from primary care to prevent child maltreatment does not consistently demonstrate benefit. We found no evidence on possible harms of these interventions. New studies that address a comprehensive array of risk factors and evaluate outcomes over the long term may help identify effective, generalizable, and acceptable interventions.
AN  - 30525342
AU  - Viswanathan,
AU  - M.
AU  - Fraser,
AU  - J.
AU  - G.
AU  - Pan,
AU  - H.
AU  - Morgenlander,
AU  - M.
AU  - McKeeman,
AU  - J.
AU  - L.
AU  - Forman-Hoffman,
AU  - V.
AU  - L.
AU  - Hart,
AU  - L.
AU  - C.
AU  - Zolotor,
AU  - A.
AU  - J.
AU  - Lohr,
AU  - K.
AU  - N.
AU  - Patel,
AU  - S.
AU  - V.
AU  - Jonas,
AU  - D.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
L1  - internal-pdf://0095025821/Viswanathan-2018.pdf
PY  - 2018
SP  - 11
T2  - Agency for Healthcare Research and Quality
TI  - Primary Care Interventions to Prevent Child Maltreatment: An Evidence Review for the U.S. Preventive Services Task Force
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30525342
ER  -
TY  - JOUR
AB  - The purpose of this meta-analysis was to examine the effect of physical activity interventions on youth diagnosed with autism spectrum disorder. Standard meta-analytical procedures determining inclusion criteria, literature searches in electronic databases, coding procedures, and statistical methods were used to identify and synthesize articles retained for analysis. Hedge&#039;s g (1988) was utilized to interpret effect sizes and quantify research findings. Moderator and outcome variables were assessed using coding procedures. 

A total of 29 studies with 30 independent samples (N=1009) were utilized in this analysis. Results from meta-analyses indicated an overall moderate effect (g=0.62). Several outcomes indicated moderate-to-large effects (g0.5); specifically, moderate to large positive effects were revealed for participants exposed to interventions targeting the development of manipulative skills, locomotor skills, skill-related fitness, social functioning, and muscular strength and endurance. 

Moderator analyses were conducted to explain variance between groups; environment was the only subgrouping variable (intervention characteristics) to produce a significant difference (Q(B)=5.67, P&lt;0.05) between moderators. While no significant differences were found between other moderators, several trends were apparent within groups in which experimental groups outperformed control groups. Autism Res2018, 11: 818-833. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. Lay 

Summary
Results of the meta-analysisa method for synthesizing researchshowed physical activity interventions to have a moderate or large effect on a variety of outcomes, including for the development of manipulative skills, locomotor skills, skill-related fitness, social functioning, and muscular strength and endurance. The authors conclude that physical activity&#039;s standing as an evidence-based strategy for youth with ASD is reinforced.
AD  - [Healy, Sean] Univ Delaware, Dept Behav Hlth &amp; Nutr, 26 North Coll Ave, Newark, DE 19716 USA. [Nacario, Adam; Braithwaite, Rock E.; Hopper, Chris] Humboldt State Univ, Dept Kinesiol &amp; Recreat Adm, Arcata, CA 95521 USA.Healy, S (reprint author), Univ Delaware, Dept Behav Hlth &amp; Nutr, 26 North Coll Ave, Newark, DE 19716 USA.healys@udel.edu
AN  - WOS:000436797200001
AU  - Healy,
AU  - S.
AU  - Nacario,
AU  - A.
AU  - Braithwaite,
AU  - R.
AU  - E.
AU  - Hopper,
AU  - C.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/aur.1955
J2  - Autism Res.
KW  - Exercise
KW  - ASD
KW  - evidence-based strategy
KW  - sport
KW  - youth
KW  - high-functioning autism
KW  - intellectual disabilities
KW  - motor-skills
KW  - activity participation
KW  - psychiatric-disorders
KW  - teaching-children
KW  - aerobic exercise
KW  - publication bias
KW  - self-regulation
KW  - young-children
KW  - Behavioral Sciences
KW  - Psychology
L1  - internal-pdf://3507290911/Healy-2018-The effect of physical activity int.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GL0RGTimes Cited: 0Cited Reference Count: 109Healy, Sean Nacario, Adam Braithwaite, Rock E. Hopper, Chris03WileyHoboken1939-3806
PY  - 2018
SP  - 818-833
T2  - Autism Research
TI  - The effect of physical activity interventions on youth with autism spectrum disorder: A meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000436797200001
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1002/aur.1955
VL  - 11
ER  -
TY  - JOUR
AB  - Behavioral parenting interventions can enhance positive parenting practice, which is crucial in preventing maltreatment and promoting child well-being. Primary care has been increasingly recognized as an underutilized platform to widely disseminate evidence-based parenting interventions, given parents&#039; ongoing access to primary care without stigma and the perceptions toward health-care providers as a trustworthy source of information about positive parenting. 

This study sought to explore the effects of primary care-based parenting interventions on parenting practice and child behavioral outcomes while examining the types of and the theories of change underlying these interventions. The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. 

Randomized controlled trials or quasi-experimental studies of interventions targeting caregivers of children aged between 1 and 17 were included in the review. Information sources included electronic databases, relevant government and private organizational websites, and expert consultations. 

The final sample included 17 studies focusing on 10 interventions. Positive results were found in knowledge gain, locus of control, monitoring, parent-child interactions, and negative discipline. Child behavior outcomes were inconsistent as most studies reported nonsignificant changes while one study reported significant intervention effects on various externalizing behaviors. A limited number of studies described the process of adapting, installing, and implementing the interventions in primary care. 

Future studies should examine the types, dosages, and delivery formats that are most suitable and sustainable in the context of primary care to maximize its utility in promoting child well-being while preventing maltreatment through integrated behavioral parenting interventions.
AD  - Moon, Deborah J. 1 School of Social Welfare, University of Kansas, Lawrence, KS, USA.Damman, Jeri L. 1 School of Social Welfare, University of Kansas, Lawrence, KS, USA.Romero, Aly. 1 School of Social Welfare, University of Kansas, Lawrence, KS, USA.
AN  - 30064299
AU  - Moon,
AU  - D.
AU  - J.
AU  - Damman,
AU  - J.
AU  - L.
AU  - Romero,
AU  - A.
DA  - Jul 31
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1524838018774424
DP  - Ovid Technologies
J2  - Trauma Violence Abuse Rev J
L1  - internal-pdf://2296977577/Moon-2018-The Effects of Primary Care-Based Pa.pdf
LA  - English
N1  - Moon, Deborah JDamman, Jeri LRomero, Aly
PY  - 2018
SP  - 1524838018774424
T2  - Trauma Violence &amp; Abuse
TI  - The Effects of Primary Care-Based Parenting Interventions on Parenting and Child Behavioral Outcomes: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30064299
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30064299&amp;id=doi:10.1177%2F1524838018774424&amp;issn=1524-8380&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1524838018774424&amp;pages=1524838018774424&amp;date=2018&amp;title=Trauma+Violence+%26+Abuse&amp;atitle=The+Effects+of+Primary+Care-Based+Parenting+Interventions+on+Parenting+and+Child+Behavioral+Outcomes%3A+A+Systematic+Review.&amp;aulast=Moon&amp;pid=%3Cauthor%3EMoon+DJ%3C%2Fauthor%3E%3CAN%3E30064299%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Background**
The global prevalence of childhood and adolescent obesity is high. Lifestyle changes towards a healthy diet, increased physical activity and reduced sedentary activities are recommended to prevent and treat obesity. Evidence suggests that changing these health behaviours can benefit cognitive function and school achievement in children and adolescents in general. There are various theoretical mechanisms that suggest that children and adolescents with excessive body fat may benefit particularly from these interventions.

**Objectives**
To assess whether lifestyle interventions (in the areas of diet, physical activity, sedentary behaviour and behavioural therapy) improve school achievement, cognitive function (e.g. executive functions) and/or future success in children and adolescents with obesity or overweight, compared with standard care, waiting‐list control, no treatment, or an attention placebo control group.

**Search methods**
In February 2017, we searched CENTRAL, MEDLINE and 15 other databases. We also searched two trials registries, reference lists, and handsearched one journal from inception. We also contacted researchers in the field to obtain unpublished data.

**Selection criteria**
We included randomised and quasi‐randomised controlled trials (RCTs) of behavioural interventions for weight management in children and adolescents with obesity or overweight. We excluded studies in children and adolescents with medical conditions known to affect weight status, school achievement and cognitive function. We also excluded self‐ and parent‐reported outcomes.

**Data collection and analysis**
Four review authors independently selected studies for inclusion. Two review authors extracted data, assessed quality and risks of bias, and evaluated the quality of the evidence using the GRADE approach. We contacted study authors to obtain additional information. We used standard methodological procedures expected by Cochrane. Where the same outcome was assessed across different intervention types, we reported standardised effect sizes for findings from single‐study and multiple‐study analyses to allow comparison of intervention effects across intervention types. To ease interpretation of the effect size, we also reported the mean difference of effect sizes for single‐study outcomes.

**Main results**
We included 18 studies (59 records) of 2384 children and adolescents with obesity or overweight. Eight studies delivered physical activity interventions, seven studies combined physical activity programmes with healthy lifestyle education, and three studies delivered dietary interventions. We included five RCTs and 13 cluster‐RCTs. The studies took place in 10 different countries. Two were carried out in children attending preschool, 11 were conducted in primary/elementary school‐aged children, four studies were aimed at adolescents attending secondary/high school and one study included primary/elementary and secondary/high school‐aged children. The number of studies included for each outcome was low, with up to only three studies per outcome. The quality of evidence ranged from high to very low and 17 studies had a high risk of bias for at least one item. None of the studies reported data on additional educational support needs and adverse events.

Compared to standard practice, analyses of physical activity‐only interventions suggested high‐quality evidence for improved mean cognitive executive function scores. The mean difference (MD) was 5.00 scale points higher in an after‐school exercise group compared to standard practice (95% confidence interval (CI) 0.68 to 9.32; scale mean 100, standard deviation 15; 116 children, 1 study). There was no statistically significant beneficial effect in favour of the intervention for mathematics, reading, or inhibition control. The standardised mean difference (SMD) for mathematics was 0.49 (95% CI ‐0.04 to 1.01; 2 studies, 255 children, moderate‐quality evidence) and for reading was 0.10 (95% CI ‐0.30 to 0.49; 2 studies, 308 children, moderate‐quality evidence). The MD for inhibition control was ‐1.55 scale points (95% CI ‐5.85 to 2.75; scale range 0 to 100; SMD ‐0.15, 95% CI ‐0.58 to 0.28; 1 study, 84 children, very low‐quality evidence). No data were available for average achievement across subjects taught at school.

There was no evidence of a beneficial effect of physical activity interventions combined with healthy lifestyle education on average achievement across subjects taught at school, mathematics achievement, reading achievement or inhibition control. The MD for average achievement across subjects taught at school was 6.37 points lower in the intervention group compared to standard practice (95% CI ‐36.83 to 24.09; scale mean 500, scale SD 70; SMD ‐0.18, 95% CI ‐0.93 to 0.58; 1 study, 31 children, low‐quality evidence). The effect estimate for mathematics achievement was SMD 0.02 (95% CI ‐0.19 to 0.22; 3 studies, 384 children, very low‐quality evidence), for reading achievement SMD 0.00 (95% CI ‐0.24 to 0.24; 2 studies, 284 children, low‐quality evidence), and for inhibition control SMD ‐0.67 (95% CI ‐1.50 to 0.16; 2 studies, 110 children, very low‐quality evidence). No data were available for the effect of combined physical activity and healthy lifestyle education on cognitive executive functions.

There was a moderate difference in the average achievement across subjects taught at school favouring interventions targeting the improvement of the school food environment compared to standard practice in adolescents with obesity (SMD 0.46, 95% CI 0.25 to 0.66; 2 studies, 382 adolescents, low‐quality evidence), but not with overweight. Replacing packed school lunch with a nutrient‐rich diet in addition to nutrition education did not improve mathematics (MD ‐2.18, 95% CI ‐5.83 to 1.47; scale range 0 to 69; SMD ‐0.26, 95% CI ‐0.72 to 0.20; 1 study, 76 children, low‐quality evidence) and reading achievement (MD 1.17, 95% CI ‐4.40 to 6.73; scale range 0 to 108; SMD 0.13, 95% CI ‐0.35 to 0.61; 1 study, 67 children, low‐quality evidence).

**Authors&#039; conclusions**
Despite the large number of childhood and adolescent obesity treatment trials, we were only able to partially assess the impact of obesity treatment interventions on school achievement and cognitive abilities. School and community‐based physical activity interventions as part of an obesity prevention or treatment programme can benefit executive functions of children with obesity or overweight specifically. Similarly, school‐based dietary interventions may benefit general school achievement in children with obesity. These findings might assist health and education practitioners to make decisions related to promoting physical activity and healthy eating in schools. Future obesity treatment and prevention studies in clinical, school and community settings should consider assessing academic and cognitive as well as physical outcomes.
AN  - CD009728
AU  - Martin,
AU  - A.
AU  - Booth,
AU  - J.
AU  - Laird,
AU  - Y.
AU  - Sproule,
AU  - J.
AU  - Reilly,
AU  - J.
AU  - Saunders,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009728.pub3
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Achievement
KW  - Educational Status
KW  - Exercise
KW  - Life Style
KW  - Executive Function
KW  - Mathematics
KW  - Overweight [psychology] [therapy]
KW  - Pediatric Obesity [psychology] [therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Sensitivity and Specificity
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Physical activity, diet and other behavioural interventions for improving cognition and school achievement in children and adolescents with obesity or overweight
UR  - http://dx.doi.org/10.1002/14651858.CD009728.pub3
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Adolescent substance use, a major problem in the United States, has a significant negative effect on both short- and long-term mental and physical health. Physical activity (PA) may offer potentially effective strategies to combat substance use in youth. Like substance use, PA behaviors developed during adolescence persist into adulthood, so adolescence may be an ideal period in which to implement PA interventions to prevent substance abuse. However, there are no known systematic literature reviews of PA-based interventions that target substance use in adolescence.

**OBJECTIVES:** 
To review PA interventions for adolescents, including research designs, intervention characteristics, and measures of substance use.

**METHODS: **
Five databases were searched for articles published in English peer-reviewed journals. Search terms were related to the adolescent population, substance use, and PA interventions.

**RESULTS: **
17 articles fit inclusion criteria. The results suggest that PA interventions may decrease substance use in teens. A majority of the interventions were delivered in high schools. Substance use measures/outcomes included intention or willingness to use, cessation, and actual use. Alcohol use was measured most, followed by marijuana and tobacco use. Although most of the studies utilized group sessions to deliver interventions, decreased substance use was also associated with one-time, multi-health consultations. 

**Conclusions/Importance:** 
School-based interventions targeting multiple health behaviors may offer a particularly effective and efficient way to decrease substance use in adolescents.
AD  - Simonton, Amanda J. a School of Nursing, The University of Texas at Austin , Texas , USA.Young, Cara C. a School of Nursing, The University of Texas at Austin , Texas , USA.Johnson, Karen E. a School of Nursing, The University of Texas at Austin , Texas , USA.
AN  - 29608379
AU  - Simonton,
AU  - A.
AU  - J.
AU  - Young,
AU  - C.
AU  - C.
AU  - Johnson,
AU  - K.
AU  - E.
DA  - Apr 02
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/10826084.2018.1452338
DP  - Ovid Technologies
J2  - Subst Use Misuse
L1  - internal-pdf://1936530001/Simonton-2018-Physical Activity Interventions.pdf
LA  - English
N1  - Simonton, Amanda JYoung, Cara CJohnson, Karen E
PY  - 2018
SP  - 1-17
T2  - Substance Use &amp; Misuse
TI  - Physical Activity Interventions to Decrease Substance Use in Youth: A Review of the Literature
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29608379
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29608379&amp;id=doi:10.1080%2F10826084.2018.1452338&amp;issn=1082-6084&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-17&amp;date=2018&amp;title=Substance+Use+%26+Misuse&amp;atitle=Physical+Activity+Interventions+to+Decrease+Substance+Use+in+Youth%3A+A+Review+of+the+Literature.&amp;aulast=Simonton&amp;pid=%3Cauthor%3ESimonton+AJ%3C%2Fauthor%3E%3CAN%3E29608379%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/pdf/10.1080/10826084.2018.1452338?needAccess=true
ER  -
TY  - JOUR
AB  - **CONTEXT:**
Parent-child book reading (PCBR) is effective at improving young children&#039;s language, literacy, brain, and cognitive development. The psychosocial effects of PCBR interventions are unclear.

**OBJECTIVE:**
To systematically review and synthesize the effects of PCBR interventions on psychosocial functioning of children and parents.

**DATA SOURCES:**
We searched ERIC, PsycINFO, Medline, Embase, PubMed, Applied Social Sciences Index and Abstracts, Social Services Abstracts, Sociological Abstracts, Family and Society Studies Worldwide, and Social Work Abstracts. We hand searched references of previous literature reviews.

**STUDY SELECTION:**
Randomized controlled trials.

DATA EXTRACTION:
By using a standardized coding scheme, data were extracted regarding sample, intervention, and study characteristics.

**RESULTS:**
We included 19 interventions (3264 families). PCBR interventions improved the psychosocial functioning of children and parents compared with controls (standardized mean difference: 0.185; 95% confidence interval: 0.077 to 0.293). The assumption of homogeneity was rejected (Q = 40.010; P &lt; .01). Two moderator variables contributed to between-group variance: method of data collection (observation less than interview; Q(b) = 7.497; P &lt; .01) and rater (reported by others less than self-reported; Q(b) = 21.368; P &lt; .01). There was no significant difference between effects of PCBR interventions on psychosocial outcomes of parents or children (Q(b) = 0.376; P = .540).

**LIMITATIONS:**
The ratio of moderating variables to the included studies limited interpretation of the findings.

**CONCLUSIONS:**
PCBR interventions are positively and significantly beneficial to the psychosocial functioning of both children and parents.
AD  - [Xie, Qian-Wen; Chan, Celia H. Y.; Chan, Cecilia L. W.] Univ Hong Kong, Dept Social Work &amp; Social Adm, Pokfulam, Hong Kong, Peoples R China. [Ji, Qingying] Shanghai Childrens Med Ctr, Shanghai, Peoples R China.Chan, CLW (reprint author), Univ Hong Kong, Room 545,Jockey Club Tower, Pokfulam, Hong Kong, Peoples R China.cecichan@hku.hk
AN  - WOS:000429276200018
AU  - Xie,
AU  - Q.
AU  - W.
AU  - Chan,
AU  - C.
AU  - H.
AU  - Y.
AU  - Ji,
AU  - Q.
AU  - Y.
AU  - Chan,
AU  - C.
AU  - L.
AU  - W.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2017-2675
J2  - Pediatrics
KW  - randomized controlled-trial
KW  - preschool language delay
KW  - young-children
KW  - family literacy
KW  - school readiness
KW  - publication bias
KW  - chronic illness
KW  - health-care
KW  - low-income
KW  - high-risk
KW  - Pediatrics
L1  - internal-pdf://3926209695/Xie-2018-Psychosocial Effects of Parent-Child.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GB7SUTimes Cited: 0Cited Reference Count: 89Xie, Qian-Wen Chan, Celia H. Y. Ji, Qingying Chan, Cecilia L. W.03Amer acad pediatricsElk grove village1098-4275
PY  - 2018
SP  - 12
T2  - Pediatrics
TI  - Psychosocial Effects of Parent-Child Book Reading Interventions: A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000429276200018
UR  - http://pediatrics.aappublications.org/content/pediatrics/141/4/e20172675.full.pdf
VL  - 141
ER  -
TY  - JOUR
AB  - The purpose of this study was to evaluate the efficacy of mindfulness-based interventions including mindful movements such as yoga on attention and executive function in children and adolescents. Systematic searches were conducted on five databases (PubMed, PsycINFO, CINAHL, Web of Science, and Scopus). 

Included studies consisting of randomized or quasi-randomized controlled trials with a mindfulness-based intervention were assessed for quality, and relevant data was extracted and collated. Thirteen randomized control trials were identified as meeting inclusion criteria, including mindfulness-based psychological interventions (n = 7), yoga (n = 3), and traditional meditation techniques (n = 2). Studies recruited adolescents or children that were typically developing, diagnosed with attention-deficit hyperactivity disorder, orphans, or had reading difficulties, or in correctional schools/institutions. 

The quality of the 13 studies ranged from low to high based on the PEDro (Physiotherapy Evidence Database) scale with the average score of 6.62 out of the highest possible score of 11 (the higher the score, the higher the quality). Five of the 13 studies found a statistically significant intervention effect for at least one outcome measure of attention or executive function with medium to large effect sizes (0.3-32.03). 

Mindfulness-based interventions are a promising approach to targeting attention and executive function in children and adolescence, especially with the use of computerized measures as outcome measures. All identified studies included interventions with multiple treatment components, so the effects attributable to mindfulness-based training still remain undetermined. 

Further quality trials are needed to assess the effectiveness of mindfulness-based interventions in enhancing attention and executive function in children and adolescents.
AN  - WOS:000422842100005
AU  - Mak,
AU  - C.
AU  - Whittingham,
AU  - K.
AU  - Cunnington,
AU  - R.
AU  - Boyd,
AU  - R.
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s12671-017-0770-6
L1  - internal-pdf://0541300314/Mak-2018-Efficacy of Mindfulness-Based Interve.pdf
PY  - 2018
SP  - 59-78
T2  - Mindfulness
TI  - Efficacy of Mindfulness-Based Interventions for Attention and Executive Function in Children and Adolescents-a Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000422842100005
UR  - https://link.springer.com/article/10.1007%2Fs12671-017-0770-6
UR  - https://link.springer.com/content/pdf/10.1007%2Fs12671-017-0770-6.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - **Importance: **
Childhood and adolescence self-regulation (SR) is gaining importance as a target of intervention because of mounting evidence of its positive associations with health, social and educational outcomes.

**Objective: **
To conduct a systematic review and meta-analysis of rigorously evaluated interventions to improve self-regulation in children and adolescents.

**Data Sources: **
Keyword searches of the PsycINFO, PubMed, EMBASE, CINAHL Plus, ERIC, British Education Index, Child Development and Adolescent Studies, and CENTRAL were used to identify all studies published through July 2016.Study 

**Selection: **
To be eligible for this review, studies had to report cluster randomized trials or randomized clinical trials, evaluate universal interventions designed to improve self-regulation in children and adolescents aged 0 to 19 years, include outcomes associated with self-regulation skills, and be published in a peer-reviewed journal with the full text available in English.

**Data Extraction and Synthesis: **
A total of 14369 published records were screened, of which 147 were identified for full-text review and 49 studies reporting 50 interventions were included in the final review. Results were summarized by narrative review and meta-analysis.

**Main Outcomes and Measures: **
Self-regulation outcomes in children and adolescents.

**Results: **
This review identified 17 cluster randomized trials and 32 randomized clinical trials evaluating self-regulation interventions, which included a total of 23098 participants ranging in age from 2 to 17 years (median age, 6.0 years). Consistent improvement in self-regulation was reported in 16 of 21 curriculum-based interventions (76%), 4 of the 8 mindfulness and yoga interventions (50%), 5 of 9 family-based programs (56%), 4 of 6 exercise-based programs (67%), and 4 of 6 social and personal skills interventions (67%), or a total of 33 of 50 interventions (66%). A meta-analysis evaluating associations of interventions with self-regulation task performance scores showed a positive effect of such interventions with pooled effect size of 0.42 (95% CI, 0.32-0.53). Only 24 studies reported data on distal outcomes (29 outcomes). Positive associations were reported in 11 of 13 studies (85%) on academic achievement, 4 of 5 studies on substance abuse (80%), and in all studies reporting on conduct disorders (n=3), studies on social skills (n=2), studies on depression (n=2), studies on behavioral problems (n=2), and study on school suspensions (n=1). No effect was seen on 2 studies reporting on academic achievement, 1 study reporting on substance abuse, and 1 additional study reporting on psychological well-being.

**Conclusions and Relevance: **
A wide range of interventions were successful in improving self-regulation in children and adolescents. There was improvement in distal academic, health, and behavioral outcomes in most intervention groups compared with controls.
AD  - Pandey, Anuja. University College London Great Ormond Street Institute of Child Health, London, United ingdom.Hale, Daniel. Heriot-Watt University, Edinburgh, United ingdom.Das, Shikta. University College London Great Ormond Street Institute of Child Health, London, United ingdom.Goddings, Anne-Lise. University College London Great Ormond Street Institute of Child Health, London, United ingdom.Blakemore, Sarah-Jayne. University College London Institute of Cognitive Neuroscience, London, United ingdom.Viner, Russell M. University College London Great Ormond Street Institute of Child Health, London, United ingdom.
AN  - 29710097
AU  - Pandey,
AU  - A.
AU  - Hale,
AU  - D.
AU  - Das,
AU  - S.
AU  - Goddings,
AU  - A.
AU  - L.
AU  - Blakemore,
AU  - S.
AU  - J.
AU  - Viner,
AU  - R.
AU  - M.
DA  - Jun 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1001/jamapediatrics.2018.0232
DP  - Ovid Technologies
J2  - Jama, Pediatr
L1  - internal-pdf://0604247407/Pandey-2018-Effectiveness of Universal Self-re.pdf
LA  - English
N1  - Pandey, AnujaHale, DanielDas, ShiktaGoddings, Anne-LiseBlakemore, Sarah-JayneViner, Russell M
PY  - 2018
SP  - 566-575
T2  - JAMA Pediatrics
TI  - Effectiveness of Universal Self-regulation-Based Interventions in Children and Adolescents: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29710097
UR  - https://jamanetwork.com/journals/jamapediatrics/articlepdf/2677898/jamapediatrics_Pandey_2018_oi_180009.pdf
VL  - 172
ER  -
TY  - JOUR
AB  - **Background**
Engagement in multiple risk behaviours can have adverse consequences for health during childhood, during adolescence, and later in life, yet little is known about the impact of different types of interventions that target multiple risk behaviours in children and young people, or the differential impact of universal versus targeted approaches. Findings from systematic reviews have been mixed, and effects of these interventions have not been quantitatively estimated.

**Objectives**
To examine the effects of interventions implemented up to 18 years of age for the primary or secondary prevention of multiple risk behaviours among young people.

**Search methods**
We searched 11 databases (Australian Education Index; British Education Index; Campbell Library; Cumulative Index to Nursing and Allied Health Literature (CINAHL); Cochrane Central Register of Controlled Trials (CENTRAL), in the Cochrane Library; Embase; Education Resource Information Center (ERIC); International Bibliography of the Social Sciences; MEDLINE; PsycINFO; and Sociological Abstracts) on three occasions (2012, 2015, and 14 November 2016)). We conducted handsearches of reference lists, contacted experts in the field, conducted citation searches, and searched websites of relevant organisations.

**Selection criteria**
We included randomised controlled trials (RCTs), including cluster RCTs, which aimed to address at least two risk behaviours. Participants were children and young people up to 18 years of age and/or parents, guardians, or carers, as long as the intervention aimed to address involvement in multiple risk behaviours among children and young people up to 18 years of age. However, studies could include outcome data on children &gt; 18 years of age at the time of follow‐up. Specifically,we included studies with outcomes collected from those eight to 25 years of age. Further, we included only studies with a combined intervention and follow‐up period of six months or longer. We excluded interventions aimed at individuals with clinically diagnosed disorders along with clinical interventions. We categorised interventions according to whether they were conducted at the individual level; the family level; or the school level.

**Data collection and analysis**
We identified a total of 34,680 titles, screened 27,691 articles and assessed 424 full‐text articles for eligibility. Two or more review authors independently assessed studies for inclusion in the review, extracted data, and assessed risk of bias.

We pooled data in meta‐analyses using a random‐effects (DerSimonian and Laird) model in RevMan 5.3. For each outcome, we included subgroups related to study type (individual, family, or school level, and universal or targeted approach) and examined effectiveness at up to 12 months&#039; follow‐up and over the longer term (&gt; 12 months). We assessed the quality and certainty of evidence using the Grades of Recommendation, Assessment, Development and Evaluation (GRADE) approach.

**Main results**
We included in the review a total of 70 eligible studies, of which a substantial proportion were universal school‐based studies (n = 28; 40%). Most studies were conducted in the USA (n = 55; 79%). On average, studies aimed to prevent four of the primary behaviours. Behaviours that were most frequently addressed included alcohol use (n = 55), drug use (n = 53), and/or antisocial behaviour (n = 53), followed by tobacco use (n = 42). No studies aimed to prevent self‐harm or gambling alongside other behaviours.

Evidence suggests that for multiple risk behaviours, universal school‐based interventions were beneficial in relation to tobacco use (odds ratio (OR) 0.77, 95% confidence interval (CI) 0.60 to 0.97; n = 9 studies; 15,354 participants) and alcohol use (OR 0.72, 95% CI 0.56 to 0.92; n = 8 studies; 8751 participants; both moderate‐quality evidence) compared to a comparator, and that such interventions may be effective in preventing illicit drug use (OR 0.74, 95% CI 0.55 to 1.00; n = 5 studies; 11,058 participants; low‐quality evidence) and engagement in any antisocial behaviour (OR 0.81, 95% CI 0.66 to 0.98; n = 13 studies; 20,756 participants; very low‐quality evidence) at up to 12 months&#039; follow‐up, although there was evidence of moderate to substantial heterogeneity (I&sup2; = 49% to 69%). Moderate‐quality evidence also showed that multiple risk behaviour universal school‐based interventions improved the odds of physical activity (OR 1.32, 95% CI 1.16 to 1.50; I&sup2; = 0%; n = 4 studies; 6441 participants). We considered observed effects to be of public health importance when applied at the population level. Evidence was less certain for the effects of such multiple risk behaviour interventions for cannabis use (OR 0.79, 95% CI 0.62 to 1.01; P = 0.06; n = 5 studies; 4140 participants; I&sup2; = 0%; moderate‐quality evidence), sexual risk behaviours (OR 0.83, 95% CI 0.61 to 1.12; P = 0.22; n = 6 studies; 12,633 participants; I&sup2; = 77%; low‐quality evidence), and unhealthy diet (OR 0.82, 95% CI 0.64 to 1.06; P = 0.13; n = 3 studies; 6441 participants; I&sup2; = 49%; moderate‐quality evidence). It is important to note that some evidence supported the positive effects of universal school‐level interventions on three or more risk behaviours.

For most outcomes of individual‐ and family‐level targeted and universal interventions, moderate‐ or low‐quality evidence suggests little or no effect, although caution is warranted in interpretation because few of these studies were available for comparison (n &le; 4 studies for each outcome).

Seven studies reported adverse effects, which involved evidence suggestive of increased involvement in a risk behaviour among participants receiving the intervention compared to participants given control interventions.

We judged the quality of evidence to be moderate or low for most outcomes, primarily owing to concerns around selection, performance, and detection bias and heterogeneity between studies.

**Authors&#039; conclusions**
Available evidence is strongest for universal school‐based interventions that target multiple‐ risk behaviours, demonstrating that they may be effective in preventing engagement in tobacco use, alcohol use, illicit drug use, and antisocial behaviour, and in improving physical activity among young people, but not in preventing other risk behaviours. Results of this review do not provide strong evidence of benefit for family‐ or individual‐level interventions across the risk behaviours studied. However, poor reporting and concerns around the quality of evidence highlight the need for high‐quality multiple‐ risk behaviour intervention studies to further strengthen the evidence base in this field.
AU  - MacArthur,
AU  - G.
AU  - Caldwell,
AU  - D.
AU  - M.
AU  - Redmore,
AU  - J.
AU  - Watkins,
AU  - S.
AU  - H.
AU  - Kipping,
AU  - R.
AU  - White,
AU  - J.
AU  - Chittleborough,
AU  - C.
AU  - Langford,
AU  - R.
AU  - Er,
AU  - V.
AU  - Lingam,
AU  - R.
AU  - Pasch,
AU  - K.
AU  - Gunnell,
AU  - D.
AU  - Hickman,
AU  - M.
AU  - Campbell,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /cdsr/doi/10.1002/14651858.CD009927.pub2/full
L1  - internal-pdf://1697363301/MacArthur-2018-Individual‐, family‐, and schoo.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Individual‐, family‐, and school‐level interventions targeting multiple risk behaviours in young people
VL  - 10
ER  -
TY  - JOUR
AB  - Nondigital board games are being used to engage players and impact outcomes in health and medicine across diverse populations and contexts. This systematic review and meta-analysis describes and summarizes their impact based on randomized and nonrandomized controlled trials. 

An electronic search resulted in a review of n=21 eligible studies. Sample sizes ranged from n=17 to n=3110 (n=6554 total participants). A majority of the board game interventions focused on education to increase health-related knowledge and behaviors (76%, n=16). Outcomes evaluated included self-efficacy, attitudes/beliefs, biological health indicators, social functioning, anxiety, and executive functioning, in addition to knowledge and behaviors. Using the Cochrane Collaboration tool for assessing bias, most studies (52%, n=11) had an unclear risk of bias (33% [n=7] had a high risk and 14% [n=3] had a low risk). Statistical tests of publication bias were not significant. 

A random-effects meta-analysis showed a large average effect of board games on health-related knowledge (d*=0.82, 95% confidence interval; CI [0.15-1.48]), a small-to-moderate effect on behaviors (d*=0.33, 95% CI [0.16-0.51]), and a small-to-moderate effect on biological health indicators (d*=0.37, 95% CI [0.21-0.52]). 

The findings contribute to the literature on games and gamified approaches in healthcare. Future research efforts should aim for more consistent high scientific standards in their evaluation protocols and reporting methodologies to provide a stronger evidence base.
AD  - [Gauthier, Andrea] Univ Toronto, Inst Med Sci, Fac Med, 3359 Mississauga Rd, Mississauga, ON L5L 2A9, Canada. [Kato, Pamela M.; Dunwell, Ian; Lameras, Petros] Coventry Univ, Sch Comp Elect &amp; Math, Fac Engn Environm &amp; Comp, Coventry, W Midlands, England. [Bul, Kim C. M.] Coventry Univ, Ctr Innovat Res Life Course CIRAL, Fac Hlth &amp; Life Sci, Coventry, W Midlands, England. [Walker-Clarke, Aimee] Univ Warwick, Int Digital Lab, Dept Engn Psychol, Warwick Mfg Grp, Coventry, W Midlands, England.Gauthier, A (reprint author), Univ Toronto, Inst Med Sci, Fac Med, 3359 Mississauga Rd, Mississauga, ON L5L 2A9, Canada.andrea.gauthier@utoronto.ca
AN  - WOS:000445694400001
AU  - Gauthier,
AU  - A.
AU  - Kato,
AU  - P.
AU  - M.
AU  - Bul,
AU  - K.
AU  - C.
AU  - M.
AU  - Dunwell,
AU  - I.
AU  - Walker-Clarke,
AU  - A.
AU  - Lameras,
AU  - P.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1089/g4h.2018.0017
J2  - Games Health J.
KW  - Board games
KW  - Serious games
KW  - Health education
KW  - Psychoeducation
KW  - Meta-analysis
KW  - randomized controlled-trial
KW  - serious games
KW  - video games
KW  - educational
KW  - games
KW  - children
KW  - dementia
KW  - adolescents
KW  - outcomes
KW  - design
KW  - promotion
KW  - Health Care Sciences &amp; Services
KW  - Public, Environmental &amp; Occupational
KW  - Health
KW  - Rehabilitation
L1  - internal-pdf://0900178781/Gauthier-2018-Board Games for Health_ A System.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GU9TLTimes Cited: 0Cited Reference Count: 69Gauthier, Andrea Kato, Pamela M. Bul, Kim C. M. Dunwell, Ian Walker-Clarke, Aimee Lameras, PetrosPfizer; Social Sciences and Humanities Research Council of CanadaThe authors wish to thank Ouarda Yvray for helpful comments on the review. This work was supported by Pfizer and the Social Sciences and Humanities Research Council of Canada through a Michael Smith Foreign Study Supplement.01Mary ann liebert, incNew rochelle2161-7856
PY  - 2018
SP  - 16
T2  - Games for Health Journal
TI  - Board Games for Health: A Systematic Literature Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000445694400001
ER  -
TY  - JOUR
AB  - **Innledning** 
Vedlikeholdsbehandling med langtidsvirkende opioider (enten metadon eller buprenorfin) er et viktig deltiltak i legemiddelassistert rehabilitering (LAR). Hensikten med tiltaket er å skape et helhetlig rehabiliteringsløp for mennesker med opiatavhengighetssyndrom. Rundt 30 av Norges ca. 2300 kvinnelige LAR‐pasienter føder barn hvert år. Bruk av LAR‐legemidler under svangerskapet fører til abstinenssymptomer hos rundt halvparten av de nyfødte. Abstinenssymptomene er forbigående, og langtidsvirkningene hos barnet er uklare. Nedtrapping av LAR‐legemidlene innebærer en risiko for økt stress både hos kvinnene og fosteret, rusmiddelbruk og overdoser hos kvinnene, og potensielt alvorlige abstinenssymptomer hos fosteret. Den eksisterende nasjonale faglige retningslinjen for gravide i LAR kom ut i 2011 og anbefaler, i likhet med internasjonale retningslinjer, å opprettholde vedlikeholdsdose‐ ringen av buprenorfin eller metadon. Når den norske retningslinjen nå skal revideres, er anbefalingene om fortsatt vedlikeholdsbehandling blant dem som skal vurderes på nytt. Mye av bakgrunnen for revideringen er uenighet blant norske fagfolk om hvorvidt fordelene ved vedlikeholdsbehandling for gravide kvinner oppveier mulige ulemper for barnet. Folkehelseinstituttet har fått i oppdrag av Helsedirektoratet å lage en systematisk over‐ sikt om følgende problemstillinger: 1. Hva er effektene for mor og barn av nedtrapping av metadon eller buprenorfin sammenliknet med fortsatt vedlikeholdsbehandling under svangerskapet? 2. Hvordan går det med mor og barn når vedlikeholdsbehandlingen trappes ned under svangerskapet (prognose)? 

**Metode** 
Vi søkte i mai 2018 etter systematiske oversikter og primærstudier i følgende databaser: Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, PycINFO, CINAHL, Cochrane Database of Systematic Reviews og Epistemonikos. I tillegg gikk vi gjennom listen over inkluderte studier i en tematisk liknende norsk rapport fra 2017. To forskere gikk gjennom søketreff, selekterte studier og vurderte metodisk kvalitet (risiko for systematiske skjevheter) ved alle inkluderte studier. Vi hentet ut data fra 7 alle relevante studier og presenterte dem i tabeller. Der det var mulig slo vi sammen resultater fra flere studier i metaanalyser. Vi vurderte vår tillit til hvert effektestimat ved hjelp av &laquo;Grading of Recommendations, Assessment, Development and Evaluation&raquo; ‐ GRADE. 

**Resultat** 
Litteratursøket ga 1358 treff etter fjerning av dubletter. Av disse ekskluderte vi 1294 studier som åpenbart ikke oppfylte inklusjonskriteriene våre. Vi bestilte og vurderte 80 artikler i fulltekst, hvorav vi ekskluderte 77. Vi inkluderte tre studier, som kunne brukes til å undersøke effekt av nedtrapping versus uendret eller økt dose blant kvinner som var i LAR da de ble gravide. Vi fant ingen studier som kunne besvare spørsmålet om prognose. Alle de tre inkluderte studiene var kohortstudier; &eacute;n prospektiv, &eacute;n retrospektiv og &eacute;n med både prospektivt og retrospektivt design. Studiene fant sted i henholdsvis Irland, USA og Norge. Deltakerne i de tre studiene var til sammen 292 kvinner som var i LAR under hele svangerskapet, og deres eksponerte barn. Ingen av studiene undersøkte langtidseffekter av nedtrapping på barnet. Vi vurderte den metodiske kvaliteten ved samtlige tre studier som lav. Dette, samt svakt studiedesign, små utvalg og stor usikkerhet rundt effektestimatene, bidro til at vår tillit til resultatene gjennomgående var svært lav. Vi gjengir derfor ingen tall for resultatene i dette sammendraget. Studiene inkluderte utfall hos de nyfødte barna (forekomst av NAS‐behandling, NAS og for tidlig fødte, behandlingsvarighet, Finnegan‐skåre, Apgar‐skåre, fødselsvekt, lengde, hodeomkrets og gestasjonsalder) og hos kvinnene (stoffbruk og røyking). For samtlige utfall, bortsett fra ett, viste effektestimatene med konfidensintervaller flere sannsynlige muligheter: effekten av nedtrapping kan være fordelaktig, skadelig eller den samme, sammenliknet med effekten ved uendret eller økt dose. Effektestimatet for røyking på slutten av svangerskapet innebar både at en mindre andel kvinner i nedtrappingsgruppen, eller at en tilnærmet like stor andel kvinner i de to gruppene, vil oppgi at de røyker. 

**Diskusjon** 
Det er en styrke ved denne oversikten at våre inklusjonskriterier omfattet studier som ikke er designet for å svare på effektspørsmål. Likevel er det viktig å understreke begrensningene ved slike studier. Små, metodisk svake observasjonsstudier gir en betydelig risiko for systematiske skjevheter i resultatene. Dette gjør det vanskelig å konkludere om hva slags effekt man kan forvente av å trappe ned LAR‐legemidler under svangerskapet versus å fortsette behandlingen med uendret eller økt dose. Det er der‐ for nødvendig å se funnene i en sammenheng med den erfaringsbaserte kunnskapen, brukerkunnskapen og konteksten før en beslutning om endring i retningslinjen bør tas. Ingen av de inkluderte studiene undersøkte tiltak som lave versus høye vedlikeholds‐ doser blant gravide kvinner i LAR, nedtrapping helt til avslutning av den medikamentelle behandlingen (seponering), eller tvangstiltak. Vi fant ingen studier som inkluderte utfall hos foster, eller hos mor og barn på lang sikt, og en rekke av de enkeltutfallene vi 8 var interessert i, inngikk ikke de inkluderte studiene. Vi fant heller ingen studier av for‐ løpet til gravide kvinner som trapper ned metadon‐ eller buprenorfindosen. For å kunne gi gode forskningsbaserte svar på spørsmål om effekt av nedtrapping, bør framtidige studier både ha store nok utvalg, gode, kontrollerte og prospektive design, langtidsoppfølging av både mor og barn, og relevante utfall. 

**Konklusjon** 
Det forskningsbaserte kunnskapsgrunnlaget er så usikkert at vi ikke kan svare på spørsmålet om det er noen forskjell i effekt på utfall hos nyfødte barn når vi sammen‐ likner nedtrapping med uendret dose eller doseøkning. Det er også usikkert om ned‐ trapping kan føre til mer eller mindre rusmiddelbruk og røyking blant gravide kvinner i LAR enn uendret eller økt dose. Svært lav tillit til effektestimatene betyr ikke at det en forskjell mellom tiltakene er usannsynlig, men at det er åpent i hvilken retning eventuelle forskjeller peker. Man kan altså hverken utelukke eller konkludere med at nedtrapping gir bedre, dårligere eller lik effekt sammenliknet med uendret eller økt dose når det gjelder noen av utfallene i de inkluderte studiene.
AU  - Kornør,
AU  - K.
AU  - Flodgren,
AU  - G.
AU  - M.
AU  - Mosdøl,
AU  - A.
AU  - Strømme,
AU  - H.
AU  - Holte,
AU  - H.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/nedtrapping-av-buprenorfin-eller-metadon-for-gravide-i-legemiddelassistert-rehabilitering-lar-rapport-2018.pdf
PY  - 2018
T2  - Folkehelseinstituttet
TI  - Nedtrapping av buprenorfin eller metadon for gravide i legemiddelassistert rehabilitering (LAR)
ER  -
TY  - JOUR
AB  - **Issues**
This overview of reviews will synthesise information from existing reviews to provide a summary of the evidence for universal alcohol and illicit drug prevention strategies across different intervention settings. 

**Approach**
Academic databases, including Medline, EMBASE and PsycInfo were searched on 1 August 2016. All reviews and meta-analyses of universal alcohol and drug prevention conducted since 2006 were included. The reviews included in this overview were grouped according to the different settings where prevention strategies have been applied (i.e. family, school, college, workplace, leisure, healthcare, community, media and policy). 

**Key Findings**
Fifty-two reviews met the inclusion criteria and were included in this report. There is sufficient evidence to support universal preventive interventions for alcohol in family and school settings. In terms of reducing drug use, there is sufficient evidence to support the use of school- and leisure-based universal primary prevention strategies. Based on evidence published in the last 10 years, mass media campaigns to do not appear to be effective in reducing drug use. More evidence is needed to support preventive interventions in college, workplace, healthcare and community settings. 

**Implications**
Through the identification of settings where preventive interventions are effective, this overview can be used to guide alcohol and drug policy and the allocation of resources. 

**Conclusion**
The evidence base for universal prevention in several settings could be strengthened, guiding priorities for future research.
AD  - [Mewton, Louise; Visontay, Rachel; Chapman, Cath; Newton, Nicola; Slade, Tim; Kay-Lambkin, Frances; Teesson, Maree] Univ New South Wales, Ctr Res Excellence Mental Hlth &amp; Subst Use, Natl Drug &amp; Alcohol Res Ctr, Sydney, NSW, Australia.Mewton, L (reprint author), Natl Drug &amp; Alcohol Res Ctr, 22-32 King St, Randwick, NSW 2032, Australia.louisem@unsw.edu.au
AN  - WOS:000431986800058
AU  - Mewton,
AU  - L.
AU  - Visontay,
AU  - R.
AU  - Chapman,
AU  - C.
AU  - Newton,
AU  - N.
AU  - Slade,
AU  - T.
AU  - Kay-Lambkin,
AU  - F.
AU  - Teesson,
AU  - M.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/dar.12694
J2  - Drug Alcohol Rev.
KW  - prevention
KW  - alcohol
KW  - drugs
KW  - randomized controlled-trials
KW  - school-based prevention
KW  - substance use
KW  - cannabis use
KW  - indigenous australians
KW  - cost-effectiveness
KW  - underage
KW  - drinking
KW  - use disorders
KW  - young-people
KW  - interventions
KW  - Substance Abuse
L1  - internal-pdf://0430641464/Mewton-2018-Universal prevention of alcohol an.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GF5DTTimes Cited: 0Cited Reference Count: 80Mewton, Louise Visontay, Rachel Chapman, Cath Newton, Nicola Slade, Tim Kay-Lambkin, Frances Teesson, MareeNewton, Nicola/0000-0001-6305-2623Australian Government Department of Health; Australian Rotary Health Postdoctoral FellowshipThis review was funded by the Australian Government Department of Health. Dr Mewton is funded by an Australian Rotary Health Postdoctoral Fellowship.0WileyHoboken1465-33621
PY  - 2018
SP  - S435-S469
T2  - Drug and Alcohol Review
TI  - Universal prevention of alcohol and drug use: An overview of reviews in an Australian context
UR  - &lt;Go to ISI&gt;://WOS:000431986800058
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/dar.12694
VL  - 37
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
The aim of this study was to assess the efficacy and safety of stimulant and nonstimulant medications in children and adolescents using as an outcome measure the Attention-Deficit/Hyperactivity Disorder Rating Scale-IV (ADHD-RS-IV), and to examine the effect of medications in different ADHD subtypes (i.e., inattention and hyperactivity/impulsivity).

**METHODS: **
MEDLINE, Scopus, EMBASE, EBSCO (E-journal, CINAHL and SportDiscus), PUBMED, and The Cochrane Central Register of Controlled Trials databases were searched. Randomized controlled trials (RCTs) with parallel group or placebo-controlled studies comparing the effect of medications (stimulants or nonstimulants) in children and adolescents with ADHD were included. The main outcomes were the ADHD-RS-IV total score and subtypes (inattention and hyperactivity/impulsivity). Treatment-emergent adverse events (TEAEs) and secondary outcomes such as systolic and diastolic blood pressure, and pulse rate were considered.

**RESULTS: **
The search strategy identified 15 RCTs, including a total of 4648 children and/or adolescents diagnosed with ADHD aged 6 to 17 years old. Overall, both stimulant and nonstimulant medications reduce the ADHD-RS-IV score with a standardized mean difference (SMD) of -0.70 (confidence interval [95% CI], -0.85 to -0.55); in subgroup analyses, the SMD was -0.83 (95% CI, -1.11 to -0.54) for stimulant medications and -0.58 (95% CI, -0.69 to -0.46) for nonstimulant medications. Similar results were observed in inattention and hyperactivity/impulsivity subtypes. The placebo group also showed a medium effect SMD of -0.68 (95% CI, -0.82 to -0.54). The most frequent TEAEs for stimulant and nonstimulant medications, respectively, were decreased appetite (28.6% and 14.2%) and somnolence (4.4% and 34.1%).

**CONCLUSIONS: **
These results suggest that both stimulant and nonstimulant medications mitigate ADHD symptoms in children and adolescents, although subgroup analyses suggest a greater effectiveness of stimulant medications.
AD  - Cerrillo-Urbina, Alberto Jose. 1 Social and Health Care Research Center , Universidad de Castilla-La Mancha, Cuenca, Spain .Garcia-Hermoso, Antonio. 2 Laboratorio de Ciencias de la Actividad Fisica, el Deporte y la Salud, Facultad de Ciencias Medicas, Universidad de Santiago de Chile , USACH, Santiago, Chile .Pardo-Guijarro, Maria Jesus. 1 Social and Health Care Research Center , Universidad de Castilla-La Mancha, Cuenca, Spain .Pardo-Guijarro, Maria Jesus. 3 Faculty of Education, Universidad de Castilla-La Mancha , Cuenca, Spain .Sanchez-Lopez, Mairena. 1 Social and Health Care Research Center , Universidad de Castilla-La Mancha, Cuenca, Spain .Sanchez-Lopez, Mairena. 4 Faculty of Education, Universidad de Castilla-La Mancha , Ciudad Real, Spain .Santos-Gomez, Jose Luis. 5 Department of Psychiatry, Hospital Virgen de la Luz , Cuenca, Spain .Martinez-Vizcaino, Vicente. 1 Social and Health Care Research Center , Universidad de Castilla-La Mancha, Cuenca, Spain .Martinez-Vizcaino, Vicente. 6 Facultad de Ciencias de la Salud, Universidad Autonoma de Chile , Talca, Chile .
AN  - 29897263
AU  - Cerrillo-Urbina,
AU  - A.
AU  - J.
AU  - Garcia-Hermoso,
AU  - A.
AU  - Pardo-Guijarro,
AU  - M.
AU  - J.
AU  - Sanchez-Lopez,
AU  - M.
AU  - Santos-Gomez,
AU  - J.
AU  - L.
AU  - Martinez-Vizcaino,
AU  - V.
DA  - Jun 13
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/cap.2017.0151
DP  - Ovid Technologies
J2  - J Child Adolesc Psychopharmacol
L1  - internal-pdf://3234131144/Cerrillo-Urbina-2018-The Effects of Long-Actin.pdf
LA  - English
N1  - Using Smart Source ParsingJunCerrillo-Urbina, Alberto JoseGarcia-Hermoso, AntonioPardo-Guijarro, Maria JesusSanchez-Lopez, MairenaSantos-Gomez, Jose LuisMartinez-Vizcaino, Vicente
PY  - 2018
SP  - 13
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - The Effects of Long-Acting Stimulant and Nonstimulant Medications in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Meta-Analysis of Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29897263
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29897263&amp;id=doi:10.1089%2Fcap.2017.0151&amp;issn=1044-5463&amp;isbn=&amp;volume=&amp;issue=&amp;spage=cap&amp;pages=&amp;date=2018&amp;title=Journal+of+Child+%26+Adolescent+Psychopharmacology&amp;atitle=The+Effects+of+Long-Acting+Stimulant+and+Nonstimulant+Medications+in+Children+and+Adolescents+with+Attention-Deficit%2FHyperactivity+Disorder%3A+A+Meta-Analysis+of+Randomized+Controlled+Trials.&amp;aulast=Cerrillo-Urbina&amp;pid=%3Cauthor%3ECerrillo-Urbina+AJ%3C%2Fauthor%3E%3CAN%3E29897263%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 13
ER  -
TY  - JOUR
AB  - **CONTEXT: **
There is increasing use of antidepressants in pregnancy and hence children exposed in utero. Contradictory studies exist in the literature in which researchers report on the potential impact of antenatal antidepressant exposure on subsequent child motor development. 

**OBJECTIVE: **
Our objective in this systematic review and meta-analysis was to determine whether antenatal antidepressant exposure increases the risk of impaired motor development in children. 

**DATA SOURCES: **
We searched PsychINFO, Embase, Medline, PubMed, and Scopus up to July 24, 2017. 

**STUDY SELECTION: **
English-language cohort and case control studies in which researchers report primary data from a motor assessment of infants or children after any antidepressant exposure in pregnancy were included. 

**DATA EXTRACTION: **
Of the 329 studies identified, there were 160 articles screened, 24 were included in the systematic review, and 18 met inclusion criteria for the meta-analysis. 

**RESULTS: **
The total pooled results were based on random effects models and revealed a significant association between exposure to antidepressants during pregnancy and overall occurrence of poorer motor outcomes in children (effect size = 0.22; 95% confidence interval = 0.07 to 0.37) with a moderate degree of heterogeneity (I2 = 56.6%). 

**LIMITATIONS: **
There was variation in the measurement both of exposure and motor development across the identified study, and few followed up to later childhood or beyond. 

**CONCLUSIONS: **
A small increased risk of poorer motor development may exist for children who are exposed to antidepressant medications during pregnancy. However, the marked methodological variation among studies and the limited control for possible confounds warrants cautious interpretation of these findings. 

Copyright &copy; 2018 by the American Academy of Pediatrics. All rights reserved.
AD  - (Grove) Department of Psychiatry, Graylands Hospital, Mount Claremont, Australia (Lewis, Galbally) School of Psychology and Exercise Science, Murdoch University, 90 South St, Murdoch, WA 6150, Australia (Galbally) School of Medicine, University of Notre Dame Australia, Fremantle, Australia (Galbally) King Edward Memorial Hospital, Subiaco, AustraliaM. Galbally, School of Psychology and Exercise Science, Murdoch University, 90 South St, Murdoch, WA 6150, Australia. E-mail: m.galbally@murdoch.edu.au
AN  - 622940889
AU  - Grove,
AU  - K.
AU  - Lewis,
AU  - A.
AU  - J.
AU  - Galbally,
AU  - M.
DA  - July
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1542/peds.2018-0356
DP  - Ovid Technologies
KW  - adverse outcome
KW  - child development
KW  - developmental disorder/th [Therapy]
KW  - drug safety
KW  - effect size
KW  - functional assessment
KW  - high risk patient
KW  - high risk population
KW  - human
KW  - major depression/dt [Drug Therapy]
KW  - meta analysis
KW  - motor development
KW  - motor function test
KW  - motor performance
KW  - postnatal depression/dt [Drug Therapy]
KW  - pregnancy outcome
KW  - prenatal drug exposure
KW  - priority journal
KW  - psychomotor development
KW  - review
KW  - systematic review
KW  - antidepressant agent/dt [Drug Therapy]
KW  - antidepressant agent/to [Drug Toxicity]
KW  - serotonin uptake inhibitor/dt [Drug Therapy]
KW  - serotonin uptake inhibitor/to [Drug Toxicity]
L1  - internal-pdf://0546573085/Grove-2018-Prenatal antidepressant exposure an.pdf
LA  - English
M3  - Review
PY  - 2018
T2  - Pediatrics
TI  - Prenatal antidepressant exposure and child motor development: A meta-analysis
UR  - http://pediatrics.aappublications.org/content/pediatrics/142/1/e20180356.full.pdf?download=true
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexa&amp;AN=622940889
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1542%2Fpeds.2018-0356&amp;issn=0031-4005&amp;isbn=&amp;volume=142&amp;issue=1&amp;spage=e20180356&amp;pages=&amp;date=2018&amp;title=Pediatrics&amp;atitle=Prenatal+antidepressant+exposure+and+child+motor+development%3A+A+meta-analysis&amp;aulast=Grove&amp;pid=%3Cauthor%3EGrove+K.%3C%2Fauthor%3E%3CAN%3E622940889%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://pediatrics.aappublications.org/content/142/1/e20180356?sso=1&amp;sso_redirect_count=1&amp;nfstatus=401&amp;nftoken=00000000-0000-0000-0000-000000000000&amp;nfstatusdescription=ERROR%3a+No+local+token
UR  - http://pediatrics.aappublications.org/content/142/1/e20180356
VL  - 142 (1) (no pagination)
ER  -
TY  - JOUR
AB  - **Objective: **
To perform a systematic review of studies of lurasidone in children and/or adolescents and to present a case report aimed to add further insights into its use in clinical practice with youth. 

**Methods: **
We searched the following databases for empirical studies, of any design, focusing on the pharmacokinetics, efficacy, or safety of lurasidone in children and/or adolescents: Pubmed (Medline), OVID (PsycInfo, EMBASE+EMBASE classic, OVID Medline), Web of Knowledge, and ClinicalTrials.gov (last search January 23, 2018). 

**Results: **
From a pool of 301 potentially relevant references, we retained 12 pertinent studies (reported in 28 references), including 1 pharmacokinetics study, 1 double blind randomized controlled trial (RCT) for bipolar depression (BD) with 1 related interim analysis study of its extension phase and 1 related external posterior predictive check study, 1 double blind RCT for schizophrenia with 3 related interim analyses of its extension phase, 1 RCT and 1 case report for autism spectrum disorder, and 2 open-label studies focusing on a variety of disorders. Overall, these studies show that lurasidone is significantly more efficacious than placebo, with moderate effect sizes, and is well tolerated for BD and schizophrenia in youth. Published studies in youth have in general used doses up to 80 mg/day. Our case report suggests that high doses of lurasidone (148 mg/day) were well tolerated and might have contributed to substantial functional improvement in a 14-year old girl with psychosis and a previous history of anorexia nervosa, who had not responded to previous antipsychotics (olanzapine, risperidone, aripiprazole). 

**Conclusions: **
There is increasing evidence that lurasidone may be moderately effective and well tolerated for the treatment of BD and psychosis in youth and may have procognitive effects. Our case report suggests that future RCTs should assess the efficacy and tolerability of high doses (&gt;80 mg/day) of lurasidone in youth. 

&copy; Copyright 2018, Mary Ann Liebert, Inc., publishers 2018.
AD  - (Channing, Mitchell) Leigh House Hospital, Winchester, United Kingdom (Cortese) Academic Unit of Psychology and Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, Center for Innovation in Mental Health, University of Southampton, Highfield Campus, Building 44, Southampton SO17 1BJ, United Kingdom (Cortese) Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, United Kingdom (Cortese) Solent NHS Trust, Southampton, United Kingdom (Cortese) New York University Child Study Center, New York, NY, United States (Cortese) Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, United KingdomS. Cortese, Academic Unit of Psychology and Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, Center for Innovation in Mental Health, University of Southampton, Highfield Campus, Building 44, Southampton SO17 1BJ, United Kingdom. E-mail: samuele.cortese@soton.ac.uk
AN  - 624019035
AU  - Channing,
AU  - J.
AU  - Mitchell,
AU  - M.
AU  - Cortese,
AU  - S.
DA  - September
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/cap.2018.0046
DP  - Ovid Technologies
KW  - autism
KW  - bipolar depression
KW  - lurasidone
KW  - psychosis
KW  - systematic review
KW  - adolescent
KW  - agitation
KW  - akathisia/si [Side Effect]
KW  - amenorrhea
KW  - anorexia nervosa/dt [Drug Therapy]
KW  - anxiety disorder/si [Side Effect]
KW  - auditory hallucination/dt [Drug Therapy]
KW  - autism/dt [Drug Therapy]
KW  - bipolar depression/dt [Drug Therapy]
KW  - body weight disorder/si [Side Effect]
KW  - case report
KW  - clinical article
KW  - clinical effectiveness
KW  - clinical practice
KW  - depression/si [Side Effect]
KW  - distress syndrome/dt [Drug Therapy]
KW  - drug dose increase
KW  - drug dose reduction
KW  - drug dose titration
KW  - drug efficacy
KW  - drug safety
KW  - drug substitution
KW  - drug tolerability
KW  - drug use
KW  - drug withdrawal
KW  - epistaxis/si [Side Effect]
KW  - extrapyramidal symptom/si [Side Effect]
KW  - female
KW  - frozen shoulder/si [Side Effect]
KW  - headache/si [Side Effect]
KW  - human
KW  - low drug dose
KW  - medical history
KW  - mood disorder
KW  - multiple cycle treatment
KW  - nausea/si [Side Effect]
KW  - olfactory hallucination
KW  - optimal drug dose
KW  - pharmacokinetic parameters
KW  - predictive value
KW  - psychosis/di [Diagnosis]
KW  - psychosis/dt [Drug Therapy]
KW  - psychosocial withdrawal
KW  - randomized controlled trial (topic)
KW  - review
KW  - schizophrenia/dt [Drug Therapy]
KW  - schizophrenia/si [Side Effect]
KW  - sedation
KW  - side effect/si [Side Effect]
KW  - somnolence/si [Side Effect]
KW  - treatment duration
KW  - visual hallucination
KW  - aripiprazole/ae [Adverse Drug Reaction]
KW  - aripiprazole/cm [Drug Comparison]
KW  - aripiprazole/dt [Drug Therapy]
KW  - aripiprazole/pv [Special Situation for Pharmacovigilance]
KW  - aripiprazole/tm [Unexpected Outcome of Drug Treatment]
KW  - fluoxetine
KW  - lurasidone/ae [Adverse Drug Reaction]
KW  - lurasidone/cb [Drug Combination]
KW  - lurasidone/cm [Drug Comparison]
KW  - lurasidone/dt [Drug Therapy]
KW  - lurasidone/pv [Special Situation for Pharmacovigilance]
KW  - lurasidone/tm [Unexpected Outcome of Drug Treatment]
KW  - olanzapine/ae [Adverse Drug Reaction]
KW  - olanzapine/dt [Drug Therapy]
KW  - olanzapine/pv [Special Situation for Pharmacovigilance]
KW  - olanzapine/tm [Unexpected Outcome of Drug Treatment]
KW  - procyclidine/cb [Drug Combination]
KW  - quetiapine/dt [Drug Therapy]
KW  - risperidone/ae [Adverse Drug Reaction]
KW  - risperidone/dt [Drug Therapy]
KW  - risperidone/pv [Special Situation for Pharmacovigilance]
KW  - risperidone/tm [Unexpected Outcome of Drug Treatment]
KW  - nasogastric tube
L1  - internal-pdf://1582170207/Channing-2018-Lurasidone in Children and Adole.pdf
LA  - English
M3  - Review
PY  - 2018
SP  - 428-436
T2  - Journal of Child and Adolescent Psychopharmacology
TI  - Lurasidone in Children and Adolescents: Systematic Review and Case Report
UR  - http://www.liebertonline.com/cap
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=624019035
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1089%2Fcap.2018.0046&amp;issn=1044-5463&amp;isbn=&amp;volume=28&amp;issue=7&amp;spage=428&amp;pages=428-436&amp;date=2018&amp;title=Journal+of+Child+and+Adolescent+Psychopharmacology&amp;atitle=Lurasidone+in+Children+and+Adolescents%3A+Systematic+Review+and+Case+Report&amp;aulast=Channing&amp;pid=%3Cauthor%3EChanning+J.%3C%2Fauthor%3E%3CAN%3E624019035%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.liebertpub.com/doi/abs/10.1089/cap.2018.0046?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 28
ER  -
TY  - JOUR
AB  - Although animal models and correlational studies support a model of fetal programming as a mechanism in the transmission of risk for psychopathology from parents to children, the experimental studies that are required to empirically test the model with the human prenatal dyad are scarce. 

With a systematic review and meta-analysis of the literature, we critically examined the evidence regarding the neurobiological and behavioral changes in infants as a function of randomized clinical trials to prevent or reduce maternal depression during pregnancy, treating randomized clinical trials as experiments testing the fetal programming model. 

Based on 25 articles that met inclusion criteria, we found support for interventions designed to change maternal prenatal mood being associated with changes in offspring functioning, but with a very small effect size. Effect sizes ranged broadly, and were higher for younger children. 

The findings enhance understanding of putative mechanisms in the transmission of risk from women&#039;s prenatal depression to infants&#039; vulnerabilities to, and early signs of, the development of psychopathology. We note limitations of the literature and suggest solutions to advance understanding of how preventing or treating depression in pregnant women might disrupt the transmission of risk to the infants.
AD  - [Goodman, Sherryl H.; Cullum, Katherine A.; Kim, Christine Youngwon] Emory Univ, Atlanta, GA 30322 USA. [Dimidjian, Sona] Univ Colorado, Boulder, CO 80309 USA. [River, Laura M.] Univ Denver, Denver, CO 80208 USA.Goodman, SH (reprint author), Emory Univ, Dept Psychol, Atlanta, GA 30322 USA.sherryl.goodman@emory.edu
AN  - WOS:000440666200030
AU  - Goodman,
AU  - S.
AU  - H.
AU  - Cullum,
AU  - K.
AU  - A.
AU  - Dimidjian,
AU  - S.
AU  - River,
AU  - L.
AU  - M.
AU  - Kim,
AU  - C.
AU  - Y.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1017/s0954579418000536
J2  - Dev. Psychopathol.
KW  - randomized controlled-trial
KW  - stress-management intervention
KW  - perinatal
KW  - depression
KW  - maternal depression
KW  - child-development
KW  - massage therapy
KW  - prenatal stress
KW  - neonatal behavior
KW  - young-children
KW  - follow-up
KW  - Psychology
L1  - internal-pdf://3802139124/Goodman-2018-Opening windows of opportunities_.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: GP2MATimes Cited: 1Cited Reference Count: 72Goodman, Sherryl H. Cullum, Katherine A. Dimidjian, Sona River, Laura M. Kim, Christine Youngwon10Cambridge univ pressNew york1469-2198Si
PY  - 2018
SP  - 1179-1196
T2  - Development and Psychopathology
TI  - Opening windows of opportunities: Evidence for interventions to prevent or treat depression in pregnant women being associated with changes in offspring&#039;s developmental trajectories of psychopathology risk
UR  - &lt;Go to ISI&gt;://WOS:000440666200030
UR  - https://www.cambridge.org/core/journals/development-and-psychopathology/article/opening-windows-of-opportunities-evidence-for-interventions-to-prevent-or-treat-depression-in-pregnant-women-being-associated-with-changes-in-offsprings-developmental-trajectories-of-psychopathology-risk/BFF2949EA4D45CDBC30C063BDD9A8692
VL  - 30
ER  -
TY  - JOUR
AB  - Foster children frequently experience early trauma that significantly impacts their neurobiological, psychological and social development. This systematic review examines the comparative effectiveness of foster and kinship care interventions. 

It examines the components within each intervention, exploring their potential to benefit child and carer well-being, particularly focussing on child behaviour problems, and relational functioning. Systematic searches of electronic databases included PsycINFO, MEDLINE, Web of Science Core Collection, the Cochrane Collaborations Register of Controlled Trials (CENTRAL) and Scopus to identify randomised or quasi-randomised trials of psychosocial foster/kinship care interventions, published between 1990 and 2016. 

Seventeen studies describing 14 interventions were included. Eleven studies reported comparative benefit compared to control. Overall, effective interventions had clearly defined aims, targeted specific domains and developmental stages, provided coaching or role play, and were developed to ameliorate the effects of maltreatment and relationship disruption. 

Interventions effective in reducing behaviour problems included consistent discipline and positive reinforcement components, trauma psychoeducation, problem-solving and parent-related components. Interventions effective in improving parent-child relationships included components focussed on developing empathic, sensitive and attuned parental responses to children&#039;s needs. 

Given the prevalence of both behaviour problems and relational difficulties in foster families, targeting these needs is essential. However, interventions have tended to measure outcomes in either behavioural or relational terms. 

A more coordinated and collaborative research approach would provide a better understanding of the association between parent-child relationships and child behaviour problems. This would allow us to develop, deliver and evaluate programs that combine these components more effectively. 

Protocol Registration Number: PROSPERO CRD42016048411.
AN  - 29159486
AU  - Kemmis-Riggs,
AU  - J.
AU  - Dickes,
AU  - A.
AU  - McAloon,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-017-0247-0
L1  - internal-pdf://2716984378/Kemmis-Riggs-2018-Program Components of Psycho.pdf
PY  - 2018
SP  - 13-40
T2  - Clinical Child &amp; Family Psychology Review
TI  - Program Components of Psychosocial Interventions in Foster and Kinship Care: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29159486
UR  - https://link.springer.com/article/10.1007%2Fs10567-017-0247-0
UR  - https://link.springer.com/content/pdf/10.1007%2Fs10567-017-0247-0.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - **Background: **
Young people with attention deficit hyperactivity disorder (ADHD) often have learning and behavioral control difficulties. 

**Aim: **
The aim of this review is analyse the acute and chronic effect of physical activity (PA) on the cognition and behaviour of children and adolescents with ADHD. 

**Methods: **
Studies were identified in five databases (PubMed, SPORTDiscus, ProQuest, Web of Science, and SCOPUS), from January 2000 through to January 2017. A total of 16 interventional studies met the inclusion criteria. 

**Results/conclusions: **
PA practice of 20-30 min (intensity 40-75%) produces a positive acute effect on processing speed, working memory, planning and problem solving in young people with ADHD. However, these effects on behaviour are contradictory and vary depending on age. Chronic PA practice (&gt;= 30 min per day, &gt;= 40% intensity, three days per week, &gt;= five weeks) further improves attention, inhibition, emotional control, behaviour and motor control. The results must be treated with caution, because only 25% of the studies used confounders. Implication More research is needed to justify the causes of these effects. It is necessary to establish programs with regard to the duration, intensity, kind of exercise, and time of PA to improve cognition and behaviour in young people with ADHD taking into account potential confounders.
AD  - [Suarez-Manzano, Sara; Ruiz-Ariza, Alberto; Martinez-Lopez, Emilio J.] Univ Jaen, Dept Didact Body Express, Res Grp, Fac Humanidades &amp; Ciencias Educ D2,Lab HUM943, Campus La Lagunillas, Jaen 23071, Spain. [De La Torre-Cruz, Manuel] Univ Jaen, Res Grp, Lab HUM943, Dept Psychol,Fac Humanidades &amp; Ciencias Educ D 2, Campus Las Lagunillas, Jaen 23071, Spain.Martinez-Lopez, EJ (reprint author), Univ Jaen, Dept Didact Body Express, Res Grp, Fac Humanidades &amp; Ciencias Educ D2,Lab HUM943, Campus La Lagunillas, Jaen 23071, Spain.ssuarez@ujaen.es; arariza@ujaen.es; majecruz@ujaen.es; emilioml@ujaen.es
AN  - WOS:000433399500002
AU  - Suarez-Manzano,
AU  - S.
AU  - Ruiz-Ariza,
AU  - A.
AU  - De
AU  - La
AU  - Torre-Cruz,
AU  - M.
AU  - Martinez-Lopez,
AU  - E.
AU  - J.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.ridd.2018.03.015
J2  - Res. Dev. Disabil.
KW  - Physical exercise
KW  - Attention deficit
KW  - Cognitive performance
KW  - Physical
KW  - fitness
KW  - Adolescent
KW  - Confounder
KW  - deficit hyperactivity disorder
KW  - attention-deficit/hyperactivity
KW  - disorder
KW  - executive function
KW  - acute exercise
KW  - psychosocial treatments
KW  - worldwide prevalence
KW  - academic-performance
KW  - motor-performance
KW  - mental-disorders
KW  - aerobic exercise
KW  - Education &amp; Educational Research
KW  - Rehabilitation
L1  - internal-pdf://0857088420/Suarez-Manzano-2018-Acute and chronic effect o.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GH4UETimes Cited: 0Cited Reference Count: 45Suarez-Manzano, Sara Ruiz-Ariza, Alberto De La Torre-Cruz, Manuel Martinez-Lopez, Emilio J.Jesus, Manuel/0000-0002-8355-7239University Teaching Staff Programme [AP-2014-01185]; Research Group Physical Activity applied to Education and Health (University of Jaen, Spain); University of Jaen programs for reserch [UJA2016/08/05-R3/8]This paper has been partly supported by the University Teaching Staff Programme, implemented by the Ministry of Education, Culture and Sport of the Spanish Government [grant number AP-2014-01185]. The study was also funded by the Research Group [grant number HUM-943-AFAES] Physical Activity applied to Education and Health (University of Jaen, Spain). Support was also received from the University of Jaen programs for reserch [grant number UJA2016/08/05-R3/8].07Pergamon-elsevier science ltdOxford
PY  - 2018
SP  - 12-23
T2  - Research in Developmental Disabilities
TI  - Acute and chronic effect of physical activity on cognition and behaviour in young people with ADHD: A systematic review of intervention studies
UR  - &lt;Go to ISI&gt;://WOS:000433399500002
UR  - https://ac.els-cdn.com/S0891422218300684/1-s2.0-S0891422218300684-main.pdf?_tid=842e9664-e46a-469a-bb1b-13199845f673&amp;acdnat=1533218687_f1baf744ce4b3ed7786210b69ce4104d
VL  - 77
ER  -
TY  - JOUR
AB  - Alliance has been shown to predict treatment outcome in family-involved treatment for youth problems in several studies. However, meta-analytic research on alliance in family-involved treatment is scarce, and to date, no meta-analytic study on the alliance-outcome association in this field has paid attention to moderating variables. 

We included 28 studies reporting on the alliance-outcome association in 21 independent study samples of families receiving family-involved treatment for youth problems (N = 2126 families, M age youth ranging from 10.6 to 16.1). 

We performed three multilevel meta-analyses of the associations between three types of alliance processes and treatment outcome, and of several moderator variables. The quality of the alliance was significantly associated with treatment outcome (r = .183, p &lt; .001). Correlations were significantly stronger when alliance scores of different measurement moments were averaged or added, when families were help-seeking rather than receiving mandated care and when studies included younger children. 

The correlation between alliance improvement and treatment outcome just failed to reached significance (r = .281, p = .067), and no significant correlation was found between split alliances and treatment outcome (r = .106, p = .343). However, the number of included studies reporting on alliance change scores or split alliances was small. 

Our findings demonstrate that alliance plays a small but significant role in the effectiveness of family-involved treatment. Future research should focus on investigating the more complex systemic aspects of alliance to gain fuller understanding of the dynamic role of alliance in working with families. 

(PsycINFO Database Record (c) 2018 APA, all rights reserved)
AD  - JLJ. J. MJ. WWelmers-van de Poll, M. J.: mariannevdpoll@hotmail.com
AN  - 2017-55414-001
AU  - Welmers-van
AU  - de
AU  - Poll,
AU  - M.
AU  - Roest,
AU  - J.
AU  - Stouwe,
AU  - T.
AU  - Akker,
AU  - A.
AU  - Stams,
AU  - G.
AU  - Escudero,
AU  - V.
AU  - Overbeek,
AU  - G.
AU  - Swart,
AU  - J.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://link.springer.com/article/10.1007/s10567-017-0249-y
DP  - Ovid Technologies
L1  - internal-pdf://3412472038/Welmers-van de-2018-Alliance and treatment out.pdf
PY  - 2018
SP  - 146-170
T2  - Clinical Child and Family Psychology Review
TI  - Alliance and treatment outcome in family-involved treatment for youth problems: A three-level meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2017-55414-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10567-017-0249-y&amp;issn=1096-4037&amp;isbn=&amp;volume=21&amp;issue=2&amp;spage=146&amp;pages=146-170&amp;date=2018&amp;title=Clinical+Child+and+Family+Psychology+Review&amp;atitle=Alliance+and+treatment+outcome+in+family-involved+treatment+for+youth+problems%3A+A+three-level+meta-analysis.&amp;aulast=Welmers-van+de+Poll&amp;pid=%3Cauthor%3EWelmers-van+de+Poll%2C+M.+J%3C%2Fauthor%3E%3CAN%3E2017-55414-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899120/pdf/10567_2017_Article_249.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - In the last several decades, researchers have begun to recognize dysregulated anger as a common and debilitating psychological problem among various psychiatric populations. 

Accordingly, the treatment of anger and aggression has received increasing attention in the literature. 

The current article reviews existing meta-analyses of psychosocial intervention for anger and aggression with the aims of (1) synthesizing current research evidence for these interventions, and (2) identifying interventions characteristics associated with effectiveness in specific populations of interest.
AN  - 29279226
AU  - Lee,
AU  - A.
AU  - H.
AU  - DiGiuseppe,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.copsyc.2017.04.004
L1  - internal-pdf://3172920870/Lee-2018-Anger and aggression treatments_ a re.pdf
PY  - 2018
SP  - 65-74
T2  - Current Opinion in Psychology
TI  - Anger and aggression treatments: a review of meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=29279226
UR  - https://www.sciencedirect.com/science/article/pii/S2352250X17300520?via%3Dihub
VL  - 19
ER  -
TY  - JOUR
AB  - Over half of all youth are exposed to violence, which a growing body of literature suggests is associated with a broad range of negative developmental outcomes over the life course. However, best practices for supporting parenting are not widely applied to parents with children exposed to violence-related trauma. 

This meta-analyses seeks to synthesize the literature base of trauma-informed parenting interventions to better understand their potential impact on parenting and child outcomes. Specifically, 21 trauma-informed parenting interventions were identified that quantitatively assessed intervention effects on parenting and child outcomes. 

Six meta-analyses were conducted to assess intervention effects on (1) positive parenting practices, (2) negative parenting practices, (3) parenting stress, (4) children&#039;s internalizing problems, (5) children&#039;s externalizing problems, and (6) trauma symptoms, respectively. Moderate to large effect sizes were found for positive parenting practices (d = 0.62) as well as child internalizing problems, externalizing problems, and trauma symptoms (d = 0.48-0.59). Validity tests indicated robust findings for positive parenting and for all child outcomes. 

Additional moderator analyses support the importance of informed intervention design, showing differential findings by trauma type as well as by duration of the intervention. These findings indicate the value of evidence-based parenting interventions for violence-related trauma and support models of trauma-informed care that situate treatment in the broader social context, particularly the family. 

Results are discussed with respect to which parenting practices hold the most promise for supporting children exposed to violence-related trauma.
AD  - Lindstrom Johnson, Sarah. T. Denny Sanford School of Social and Family Dynamics, Arizona State University, Tempe, AZ, USA. sarahlj@asu.edu.Elam, Kit. T. Denny Sanford School of Social and Family Dynamics, Arizona State University, Tempe, AZ, USA.Rogers, Adam A. School of Family Life, Brigham Young University, Provo, UT, USA.Hilley, Chanler. T. Denny Sanford School of Social and Family Dynamics, Arizona State University, Tempe, AZ, USA.
AN  - 30136246
AU  - Lindstrom
AU  - Johnson,
AU  - S.
AU  - Elam,
AU  - K.
AU  - Rogers,
AU  - A.
AU  - A.
AU  - Hilley,
AU  - C.
DA  - Aug 22
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s11121-018-0943-0
DP  - Ovid Technologies
J2  - Prev Sci
L1  - internal-pdf://3419083422/Lindstrom Johns-2018-A Meta-Analysis of Parent.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingAugLindstrom Johnson, SarahElam, KitRogers, Adam AHilley, Chanler
PY  - 2018
SP  - 22
T2  - Prevention Science
TI  - A Meta-Analysis of Parenting Practices and Child Psychosocial Outcomes in Trauma-Informed Parenting Interventions after Violence Exposure
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30136246
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30136246&amp;id=doi:10.1007%2Fs11121-018-0943-0&amp;issn=1389-4986&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Prevention+Science&amp;atitle=A+Meta-Analysis+of+Parenting+Practices+and+Child+Psychosocial+Outcomes+in+Trauma-Informed+Parenting+Interventions+after+Violence+Exposure.&amp;aulast=Lindstrom+Johnson&amp;pid=%3Cauthor%3ELindstrom+Johnson+S%3C%2Fauthor%3E%3CAN%3E30136246%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs11121-018-0943-0
VL  - 22
ER  -
TY  - JOUR
AB  - Caregivers of children in alternative care face a complex range of challenges that can result in placement disruption and poor long-term outcomes. Interventions designed to help carers meet these challenges report positive outcomes. 

Nevertheless, several reviewers have reported these positive results may be mitigated by limitations in trial methodology. This review aims to systematically review these methodological challenges and limitations, to provide an analysis of the current state of the evidence base for these interventions. A systematic review was conducted into the methods used to evaluate the effectiveness of psychosocial interventions for foster and kinship carers. 

Limitations relating to internal validity, external validity and clinical heterogeneity were identified and synthesised. Seventeen studies met inclusion criteria. The quality of methods used in the included studies is mixed, with high and unknown levels of bias in the majority of trials. Heterogeneity in participant characteristics, intervention aims and outcome measures across interventions reflect the diversity of carer and child needs and make it difficult to generalise results or compare and synthesise the efficacy of different interventions. 

These factors limit the application of trial results to evidence-based clinical practice. The diverse and complex needs of this population present significant challenges to robustly evaluating interventions for foster/kinship families. Participant needs, theoretical approaches, intervention aims and outcome measures need to be better coordinated, both within trials and across the field. 

Exploratory research should be used to generate focussed and concrete hypotheses that can be robustly tested in high-quality randomised controlled trials. 

Protocol registration number: CRD 42017048415.
AD  - [Dickes, Adam; Kemmis-Riggs, Jacqueline; McAloon, John] Univ Technol Sydney, Ctr Child &amp; Adolescent Mental Hlth, Level 4 Bldg 7,67 Thomas St, Ultimo, NSW 2007, Australia.Dickes, A (reprint author), Univ Technol Sydney, Ctr Child &amp; Adolescent Mental Hlth, Level 4 Bldg 7,67 Thomas St, Ultimo, NSW 2007, Australia.Adam.P.Dickes@student.uts.edu.au
AN  - WOS:000430001000001
AU  - Dickes,
AU  - A.
AU  - Kemmis-Riggs,
AU  - J.
AU  - McAloon,
AU  - J.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10567-017-0248-z
J2  - Clin. Child Fam. Psychol. Rev.
KW  - Foster care
KW  - Alternative care
KW  - Looked after children
KW  - Maltreatment
KW  - Evidence-based practice
KW  - Methodology
KW  - looked-after children
KW  - attachment-based intervention
KW  - randomized
KW  - controlled-trials
KW  - foster-care
KW  - behavior problems
KW  - clinical-trial
KW  - young-people
KW  - follow-up
KW  - difficulties questionnaire
KW  - parenting
KW  - intervention
KW  - Psychology
L1  - internal-pdf://0208598168/Dickes-2018-Methodological Challenges to the E.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GC7VITimes Cited: 0Cited Reference Count: 126Dickes, Adam Kemmis-Riggs, Jacqueline McAloon, JohnUniversity of Technology SydneyFunding was provided by the University of Technology Sydney.03Springer/plenum publishersNew york1573-2827
PY  - 2018
SP  - 109-145
T2  - Clinical Child and Family Psychology Review
TI  - Methodological Challenges to the Evaluation of Interventions for Foster/Kinship Carers and Children: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000430001000001
UR  - https://link.springer.com/article/10.1007%2Fs10567-017-0248-z
VL  - 21
ER  -
TY  - JOUR
AB  - **Objective: **
The purpose of this study was to quantify the effect of physical activity (in both descriptive and intervention studies) on health-related quality of life (HRQOL) in children and adolescents from both healthy and chronic illness populations.

**Method: **
A systematic review of PubMed, PsycINFO, and ProQuest identified 33 studies of physical activity and HRQOL in youth, including descriptive and prepost intervention designs. 

**Results: **
In descriptive studies (N = 14), there was a small, positive association between physical activity and HRQOL based on child-reports (Hedges&#039; g = .302, p &lt; .001, 95% confidence interval, CI [.178, .426]) and a negligible association based on parent-proxy reports (Hedges&#039; g = .115, p = .101, 95% CI [-.023, .253]). Intervention studies (N = 19) yielded a small, positive effect of physical activity intervention on HRQOL based on child-reports (Hedges&#039; g = .279, p = .014, 95% CI [.057, .500]) and a medium, positive effect based on parent-proxy reports (Hedges&#039; g = .522, p = .012, 95% CI [.117, .928]). Intervention effects were attenuated by removal of a single study. Hypothesized and exploratory moderators did not moderate the relationship between physical activity and HRQOL. 

**Conclusions: **
Findings supported the primary hypothesis that physical activity was related to better HRQOL in youth, although the magnitude of these effects did not represent a minimal clinically important difference (MCID) in most studies. Future studies are needed to assess HRQOL in youth before and after exercise interventions to quantify the type, frequency, duration, and intensity of physical activity needed to change HRQOL. 

(PsycINFO Database Record (c) 2018 APA, all rights reserved)
AD  - Steele, Ric G.: rsteele@ku.eduSteele, Ric G.: Clinical Child Psychology Program, University of Kansas, 2010 Dole Human Development Center, 1000 Sunnyside Avenue, Lawrence, KS, US, 66049, rsteele@ku.eduMarker, Arwen M.: Clinical Child Psychology Program, University of Kansas, Lawrence, KS, USSteele, Ric G.: Clinical Child Psychology Program, University of Kansas, Lawrence, KS, USNoser, Amy E.: Clinical Child Psychology Program, University of Kansas, Lawrence, KS, US
AN  - 2018-46854-001
AU  - Marker,
AU  - A.
AU  - M.
AU  - Steele,
AU  - R.
AU  - G.
AU  - Noser,
AU  - A.
AU  - E.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/hea0000653
DP  - Ovid Technologies
KW  - pediatric, physical activity, health-related quality of life
KW  - *Adolescent Psychology
KW  - *Child Psychology
KW  - *Chronic Illness
KW  - *Physical Activity
KW  - *Quality of Life
KW  - Exercise
KW  - Health
KW  - Intervention
KW  - Pediatrics
KW  - Parent Report
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://0634787650/Marker-2018-Physical activity and health-relat.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2018
SP  - 893-903
T2  - Health Psychology
TI  - Physical activity and health-related quality of life in children and adolescents: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2018-46854-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2Fhea0000653&amp;issn=0278-6133&amp;isbn=&amp;volume=37&amp;issue=10&amp;spage=893&amp;pages=893-903&amp;date=2018&amp;title=Health+Psychology&amp;atitle=Physical+activity+and+health-related+quality+of+life+in+children+and+adolescents%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Marker&amp;pid=%3Cauthor%3EMarker%2C+Arwen+M%3C%2Fauthor%3E%3CAN%3E2018-46854-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 37
ER  -
TY  - JOUR
AB  - With the development of empirically supported treatments over the decades, have youth psychotherapies grown stronger? To investigate, we examined changes over time in treatment effects for four frequently treated youth mental-health problems: anxiety, depression, attention-deficit hyperactivity disorder (ADHD), and conduct disorders. 

We used PubMed and PsycINFO to search for randomized controlled trials (RCTs) that were published between January 1960 and May 2017 involving youths between the ages of 4 and 18 years. We also searched reviews and meta-analyses of youth psychotherapy research, followed reference trails in the reports we identified, and obtained additional studies identified by therapy researchers whom we contacted. 

We identified 453 RCTs (31,933 participants) spanning 53 years (1963-2016). Effect sizes for the problem-relevant outcome measures were synthesized via multilevel meta-analysis. We tracked temporal trends for each problem domain and then examined multiple study characteristics that might moderate those trends. Mean effect size increased nonsignificantly for anxiety, decreased nonsignificantly for ADHD, and decreased significantly for depression and conduct problems. Moderator analyses involving multiple study subgroups showed only a few exceptions to these surprising patterns. 

The findings suggest that new approaches to treatment design and intervention science may be needed, especially for depression and conduct problems. We suggest intensifying the search for mechanisms of change, making treatments more transdiagnostic and personalizable, embedding treatments within youth ecosystems, adapting treatments to the social and technological changes that alter youth dysfunction and treatment needs, and resisting old habits that can make treatments unduly skeuomorphic.
AN  - 30571478
AU  - Weisz,
AU  - J.
AU  - R.
AU  - Kuppens,
AU  - S.
AU  - Ng,
AU  - M.
AU  - Y.
AU  - Vaughn-Coaxum,
AU  - R.
AU  - A.
AU  - Ugueto,
AU  - A.
AU  - M.
AU  - Eckshtain,
AU  - D.
AU  - Corteselli,
AU  - K.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1745691618805436
L1  - internal-pdf://2672753153/Weisz-2018-Are Psychotherapies for Young Peopl.pdf
PY  - 2018
SP  - 1745691618805436
TI  - Are Psychotherapies for Young People Growing Stronger? Tracking Trends Over Time for Youth Anxiety, Depression, Attention-Deficit/Hyperactivity Disorder, and Conduct Problems
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30571478
ER  -
TY  - JOUR
AB  - **Background**
This is an update of the original Cochrane review first published in Issue 1, 2003, and previously updated in 2009, 2012 and 2014. Chronic pain, defined as pain that recurs or persists for more than three months, is common in childhood. Chronic pain can affect nearly every aspect of daily life and is associated with disability, anxiety, and depressive symptoms.

**Objectives**
The aim of this review was to update the published evidence on the efficacy of psychological treatments for chronic and recurrent pain in children and adolescents.

The primary objective of this updated review was to determine any effect of psychological therapy on the clinical outcomes of pain intensity and disability for chronic and recurrent pain in children and adolescents compared with active treatment, waiting‐list, or treatment‐as‐usual care.

The secondary objective was to examine the impact of psychological therapies on children&#039;s depressive symptoms and anxiety symptoms, and determine adverse events.

**Search methods**
Searches were undertaken of CENTRAL, MEDLINE, MEDLINE in Process, Embase, and PsycINFO databases. We searched for further RCTs in the references of all identified studies, meta‐analyses, and reviews, and trial registry databases. The most recent search was conducted in May 2018.

**Selection criteria**
RCTs with at least 10 participants in each arm post‐treatment comparing psychological therapies with active treatment, treatment‐as‐usual, or waiting‐list control for children or adolescents with recurrent or chronic pain were eligible for inclusion. We excluded trials conducted remotely via the Internet.

**Data collection and analysis**
We analysed included studies and we assessed quality of outcomes. We combined all treatments into one class named &#039;psychological treatments&#039;. We separated the trials by the number of participants that were included in each arm; trials with &gt; 20 participants per arm versus trials with &lt; 20 participants per arm. We split pain conditions into headache and mixed chronic pain conditions. We assessed the impact of both conditions on four outcomes: pain, disability, depression, and anxiety. We extracted data at two time points; post‐treatment (immediately or the earliest data available following end of treatment) and at follow‐up (between three and 12 months post‐treatment).

**Main results**
We identified 10 new studies (an additional 869 participants) in the updated search. The review thus included a total of 47 studies, with 2884 children and adolescents completing treatment (mean age 12.65 years, SD 2.21 years). Twenty‐three studies addressed treatments for headache (including migraine); 10 for abdominal pain; two studies treated participants with either a primary diagnosis of abdominal pain or irritable bowel syndrome, two studies treated adolescents with fibromyalgia, two studies included adolescents with temporomandibular disorders, three were for the treatment of pain associated with sickle cell disease, and two studies treated adolescents with inflammatory bowel disease. Finally, three studies included adolescents with mixed pain conditions. Overall, we judged the included studies to be at unclear or high risk of bias.

Children with headache pain

We found that psychological therapies reduced pain frequency post‐treatment for children and adolescents with headaches (risk ratio (RR) 2.35, 95% confidence interval (CI) 1.67 to 3.30, P &lt; 0.01, number needed to treat for an additional beneficial outcome (NNTB) = 2.86), but these effects were not maintained at follow‐up. We did not find a beneficial effect of psychological therapies on reducing disability in young people post‐treatment (SMD ‐0.26, 95% CI ‐0.56 to 0.03), but we did find a beneficial effect in a small number of studies at follow‐up (SMD ‐0.34, 95% CI ‐0.54 to ‐0.15). We found no beneficial effect of psychological interventions on depression or anxiety symptoms.

Children with mixed pain conditions

We found that psychological therapies reduced pain intensity post‐treatment for children and adolescents with mixed pain conditions (SMD ‐0.43, 95% CI ‐0.67 to ‐0.19, P &lt; 0.01), but these effects were not maintained at follow‐up. We did find beneficial effects of psychological therapies on reducing disability for young people with mixed pain conditions post‐treatment (SMD ‐0.34, 95% CI ‐0.54 to ‐0.15) and at follow‐up (SMD ‐0.27, 95% CI ‐0.49 to ‐0.06). We found no beneficial effect of psychological interventions on depression symptoms. In contrast, we found a beneficial effect on anxiety at post‐treatment in children with mixed pain conditions (SMD ‐0.16, 95% CI ‐0.29 to ‐0.03), but this was not maintained at follow‐up.

Across all pain conditions, we found that adverse events were reported in seven trials, of which two studies reported adverse events that were study‐related.

Quality of evidence

We found the quality of evidence for all outcomes to be low or very low, mostly downgraded for unexplained heterogeneity, limitations in study design, imprecise and sparse data, or suspicion of publication bias. This means our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect, or we have very little confidence in the effect estimate; or the true effect is likely to be substantially different from the estimate of effect.

**Authors&#039; conclusions**
Psychological treatments delivered predominantly face‐to‐face might be effective for reducing pain outcomes for children and adolescents with headache or other chronic pain conditions post‐treatment. However, there were no effects at follow‐up. Psychological therapies were also beneficial for reducing disability in children with mixed chronic pain conditions at post‐treatment and follow‐up, and for children with headache at follow‐up. We found no beneficial effect of therapies for improving depression or anxiety. The conclusions of this update replicate and add to those of a previous version of the review which found that psychological therapies were effective in reducing pain frequency/intensity for children with headache and mixed chronic pain conditions post‐treatment.
AN  - CD003968
AU  - Fisher,
AU  - E.
AU  - Law,
AU  - E.
AU  - Dudeney,
AU  - J.
AU  - Palermo,
AU  - T.
AU  - M.
AU  - Stewart,
AU  - G.
AU  - Eccleston,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1002/14651858.CD003968.pub5
KW  - Abdominal Pain [therapy]
KW  - Adolescent
KW  - Anxiety [drug therapy]
KW  - Child
KW  - Chronic Pain [etiology, psychology, *therapy]
KW  - Cognitive Behavioral Therapy
KW  - Depression [drug therapy]
KW  - Fibromyalgia [therapy]
KW  - Headache [therapy]
KW  - Hemoglobin SC Disease [complications]
KW  - Humans
KW  - Pain Management [*methods, psychology]
KW  - Psychotherapy [*methods]
KW  - Randomized Controlled Trials as Topic
KW  - Recurrence
KW  - Temporomandibular Joint Disorders [therapy]
L1  - internal-pdf://1386293580/Fisher_et_al-2018-Cochrane_Database_of_Systema.pdf
N1  - [Pain, Palliative and Supportive Care]
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological therapies for the management of chronic and recurrent pain in children and adolescents
UR  - https://doi.org//10.1002/14651858.CD003968.pub5
ER  -
TY  - JOUR
AB  - Randomized controlled trials (RCTs) have reported an inconsistent relationship about the auditory integration training (AIT) in children with autism spectrum disorders (ASD) among Chinese. The current study was to investigate the efficacy of AIT for children with ASD compared with those in control group by using meta-analysis. 

Relevant trials published were identified by an electronic search of PubMed, CENTRAL, EMBASE, WanFang, CNKI, and SinoMed databases up to December 31, 2017. Outcome of interest included childhood autism rating scale (CARS), autism behavior checklist (ABC), intelligence quotient (IQ), and autism treatment evaluation checklist (ATEC). Standardized mean difference (SMD) with 95% confidence intervals (CIs) was calculated using a random-effect model. Thirteen RCTs with 976 children with ASD were included for analysis. 

The pooled SMD showed that children with ASD had significantly lower ABC scores [summary SMD = -0.58, 95%CI = -0.79 to -0.38] and ATEC scores [summary SMD = -0.75, 95%CI = -1.05 to -0.45] in AIT group compared with that in control group. The analysis of pooled statistics put forward AIT could increase the IQ score when compared with that in control group [summary SMD = 0.59, 95%CI = 0.41-0.77]. 

A negative association was found about CARS scores between AIT group and control group. No publication bias was found and no single study had essential effect on the pooled results.

In conclusions, AIT can reduce the score of ABC and ATEC and can increase the IQ score among children with ASD in Chinese. Therefore, it is recommended for Chinese children with ASD to receive AIT.
AN  - 30429234
AU  - Li,
AU  - N.
AU  - Li,
AU  - L.
AU  - Li,
AU  - G.
AU  - Gai,
AU  - Z.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1042/BSR20181412
L1  - internal-pdf://2494485943/Li-2018-The association of auditory integratio.pdf
PY  - 2018
SP  - 21
T2  - Bioscience Reports
TI  - The association of auditory integration training in children with autism spectrum disorders among Chinese: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30429234
UR  - http://www.bioscirep.org/content/ppbioscirep/38/6/BSR20181412.full.pdf
VL  - 38
ER  -
TY  - JOUR
AB  - Varje år placeras ungef&auml;r 2 000 ungdomar på institution på grund av allvarliga beteendeproblem. Ungdomarna placeras då antingen på s&auml;rskilda ungdomshem eller på kommunala eller privata Hem f&ouml;r vård eller boende (HVB). En alternativ placering f&ouml;r dessa ungdomar &auml;r i en så kallad behandlingsfamilj. Det &auml;r en tidsbegr&auml;nsad insats d&auml;r utbildade familjehemsf&ouml;r&auml;ldrar tillsammans med ett team bedriver behandling. En version av behandlingsfamilj &auml;r Treatment Foster Care Oregon (TFCO). TFCO finns i begr&auml;nsad omfattning i Sverige sedan b&ouml;rjan av 2000-talet.

**Slutsatser**
N&auml;r ungdomar med allvarliga beteendeproblem placeras i TFCO, leder detta troligtvis till mindre fortsatt kriminalitet och f&auml;rre placeringar på låst avdelning &auml;n n&auml;r ungdomarna placeras på institution. Det &auml;r också m&ouml;jligt att TFCO leder till f&auml;rre kriminella kamrater, mindre anv&auml;ndning av narkotika och b&auml;ttre psykisk h&auml;lsa, &auml;n vid placering på institution.

TFCO kostar i genomsnitt mindre &auml;n placering på s&auml;rskilda ungdomshem och något mer &auml;n på HVB, om man r&auml;knar med att vårdtiderna &auml;r desamma. V&auml;ger man in antaganden om långsiktiga effekter &auml;r TFCO kostnadsbesparande f&ouml;r samh&auml;llet j&auml;mf&ouml;rt med placering på s&auml;rskilda ungdomshem eller HVB.Idag får cirka 30&ndash;40 ungdomar i Sverige årligen tillgång till TFCO. Om fler ska få tillgång måste fler behandlingsteam inr&auml;ttas, vilket kortsiktigt medf&ouml;r kostnader f&ouml;r utbildning och certifiering.

Alternativet till behandlingsfamiljer &auml;r institutionsvård som ofta kompletteras med olika behandlingsmetoder. Kunskapen om metodernas nytta och risker &auml;r bristf&auml;llig eftersom det saknas studier. Ur ett etiskt perspektiv &auml;r det angel&auml;get att få tillf&ouml;rlitlig kunskap om f&ouml;r- och nackdelar med de &ouml;vriga kompletterande behandlingar som anv&auml;nds.

**Sammanfattning**

**Bakgrund och syfte**
Ungdomar med allvarliga beteendeproblem har i vuxen ålder en f&ouml;rh&ouml;jd risk f&ouml;r kriminalitet, missbruk, fysisk och psykisk oh&auml;lsa samt f&ouml;r tidig d&ouml;d. Traditionellt har placering på institution (s&auml;rskilda ungdomshem eller HVB) varit den vårdform som anv&auml;nts. Syftet med denna rapport &auml;r att granska och sammanst&auml;lla det vetenskapliga underlaget f&ouml;r familjehem med ett f&ouml;rst&auml;rkt st&ouml;d, så kallade behandlingsfamiljer, i j&auml;mf&ouml;relse med institutionsplacering. Litteraturs&ouml;kningen identifierade endast en version av behandlingsfamiljer f&ouml;r målgruppen, Treatment Foster Care Oregon (TFCO).

**Metod**
Den systematiska utv&auml;rderingen genomf&ouml;rdes i enlighet med SBU:s metodik. Målgruppen var ungdomar med allvarliga beteendeproblem i åldrarna 12 till 17 år. Studierna skulle utv&auml;rdera behandlingsfamiljer i j&auml;mf&ouml;relse med institutionsvård och vara kontrollerade med h&ouml;g eller medelh&ouml;g studiekvalitet. Studierna skulle vara publicerade mellan åren 1990 och 2017. Uppf&ouml;ljningstiden skulle vara minst 12 månader efter placeringens start. Studierna utesl&ouml;ts om j&auml;mf&ouml;relsegruppen utgjordes av traditionella familjehem eller om barnen var yngre &auml;n 12 år.Den systematiska utv&auml;rderingen inkluderar &auml;ven ekonomiska aspekter. Rapporten innehåller också en inventering av vilka insatser som anv&auml;nds inom institutionsvård i Sverige, några r&ouml;ster från personer som varit placerade i TFCO och på institutioner samt en etisk analys.

**Resultat**

**Effekter av TFCO**
Sammanlagt granskades 5 893 artikelsammanfattningar. Relevans- och kvalitetsgranskningen identifierade åtta studier som motsvarade projektets inklusionskriterier, varav fem från USA, två brittiska och en svensk. Dessa studier f&ouml;ljde i de flesta fall ungdomarna under 24 månader. Sammantaget visar studierna att TFCO troligen minskar ungdomarnas kriminalitet och placering på låst avdelning, samt m&ouml;jligen &auml;ven minskar narkotikamissbruk, psykisk oh&auml;lsa samt f&ouml;rekomst av kriminella kamrater. Det vetenskapliga underlaget var otillr&auml;ckligt f&ouml;r att v&auml;rdera effekten på alkoholmissbruk, psykotiska symtom, sexuellt riskbeteende och på f&ouml;rekomsten av tonårsgraviditeter. Det saknas helt studier som belyser TFCO:s effekter på fysisk h&auml;lsa, upplevd livskvalitet, utbildning samt på yrkesanst&auml;llning. Det saknas också studier om eventuella skadliga eller o&ouml;nskade effekter av insatserna.

**Ekonomiska aspekter**
Sammanlagt granskades 314 artikelsammanfattningar. Relevans- och kvalitetsgranskningen identifierade en dansk rapport som motsvarade projektets inklusionskriterier. I rapporten presenterades en modellbaserad kostnadsint&auml;ktsanalys som visade att TFCO var kostnadsbesparande j&auml;mf&ouml;rt med institutionsvård med n&auml;rmare 900 000 kronor per ungdom i ett livstidsperspektiv. En sammanst&auml;llning av svenska kostnader f&ouml;r placeringar visade att TFCO var mindre kostsamt &auml;n institutionsvård vid s&auml;rskilt ungdomshem men något dyrare &auml;n HVB, om man r&auml;knade med att vårdtiderna var desamma.

**Praxisunders&ouml;kning**
Eftersom institutionsplacering ofta kompletteras med behandlingsmetoder kontaktades ett slumpvis urval av institutioner f&ouml;r ungdomar med beteendeproblem (svar kom från 53 av 67). Institutionerna uppgav att de anv&auml;nde 33 behandlingsmetoder och 8 mer allm&auml;nna f&ouml;rhållningss&auml;tt. Få av dessa var vetenskapligt utv&auml;rderade f&ouml;r målgruppen. Resultatet tyder på problem ut&ouml;ver bristande vetenskaplig kunskap om metoderna. Till exempel uppgav en institution av fyra att man anv&auml;nde behandlingsmetoder utan att personalen hade utbildning f&ouml;r dem. De flesta institutionerna saknade också handledning f&ouml;r metoderna. Institutionerna anv&auml;nde 18 standardiserade bed&ouml;mningsmetoder, varav fyra bed&ouml;mdes som s&auml;rskilt relevanta f&ouml;r målgruppen.

**Några r&ouml;ster om TFCO och institutionsplacering**
Personer med erfarenheter av TFCO respektive institutionsplacering hade samma uppfattningar om vad som ansågs som viktigt vid en placering; f&ouml;rtroendefulla vuxenkontakter, behandling av ursprungsfamiljen samt minskad kontakt med andra ungdomar med allvarliga beteendeproblem. Ungdomarna med upplevelse av TFCO bed&ouml;mde att de hade getts dessa viktiga komponenter, medan ungdomarna som varit institutionsplacerade inte hade getts den m&ouml;jligheten i samma utstr&auml;ckning.

**Etiska aspekter**
N&auml;r samh&auml;llet &ouml;vertar ansvaret f&ouml;r ungdomars vård så finns en s&auml;rskild skyldighet att tillgodose deras b&auml;sta. Det &auml;r ett etiskt problem att få av de behandlingsmetoder som anv&auml;nds inom institutionsvården &auml;r utv&auml;rderade. D&auml;rmed &auml;r det oklart om institutionsvård gynnar ungdomarna och lever upp till grundl&auml;ggande etiska krav på ansvarstagande från samh&auml;llets sida.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /sv/publikationer/SBU-utvarderar/behandlingsfamiljer-for-ungdomar-med-allvarliga-beteendeproblem/
L1  - internal-pdf://3787504334/behandlingsfamiljer-for-ungdomar-med-allvarlig.pdf
PY  - 2018
TI  - Behandlingsfamiljer f&ouml;r ungdomar med allvarliga beteendeproblem &ndash; Treatment Foster Care Oregon. En systematisk &ouml;versikt och utv&auml;rdering inklusive ekonomiska och etiska aspekter.
ER  -
TY  - JOUR
AB  - **Objectives: **
This review evaluates the evidence on the effects of functional family therapy (FFT) on drug abuse reduction for young people in treatment for nonopioid drug use. 

**Data and Analysis: **
We followed Campbell Collaboration guidelines to conduct a systematic review of randomized and nonrandomized trials. 

**Results: **
The search yielded two studies that met inclusion criteria. Only one study provided numerical results on the effect of FFT on drug use reduction.

**Conclusions: **
There is insufficient evidence to allow any conclusion to be drawn on the effect of FFT for young people in treatment for nonopioid drug use. There is a need for more research and particularly for more methodologically rigorous studies in the field of treatment for young drug users.
AN  - WOS:000419873100003
AU  - Filges,
AU  - T.
AU  - Andersen,
AU  - D.
AU  - Jorgensen,
AU  - A.
AU  - M.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1049731516629802
L1  - internal-pdf://3881999802/Filges-2018-Functional Family Therapy for Youn.pdf
PY  - 2018
SP  - 131-145
T2  - Research on Social Work Practice
TI  - Functional Family Therapy for Young People in Treatment for Nonopioid Drug Use: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000419873100003
UR  - http://journals.sagepub.com/doi/10.1177/1049731516629802
UR  - http://journals.sagepub.com/doi/pdf/10.1177/1049731516629802
VL  - 28
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD), the most common pediatric neurobehavioral disorder, frequently presents with coexisting reading disorders (RDs). 

Despite this, it is unclear whether medication improves symptoms and function in children with comorbid ADHD and RD. 

We present a systematic review of studies investigating the effects of ADHD medications on ADHD symptoms, academic outcomes, and neuropsychological measures in this important group. 

Copyright &copy; 2018 American Society for Clinical Pharmacology and Therapeutics
AD  - (Froehlich) Division of Developmental and Behavioral Pediatrics, Cincinnati Children&#039;s Hospital Medical center, Cincinnati, OH, United States (Froehlich) Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States (Fogler, Barbaresi, Chan) Division of Developmental Medicine, Boston Children&#039;s Hospital, Boston, MA, United States (Fogler, Barbaresi, Chan) Harvard Medical School, Boston, MA, United States (Elsayed) Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, United States (Evans) Department of Psychology, Ohio University, Athens, OH, United StatesT.E. Froehlich, Division of Developmental and Behavioral Pediatrics, Cincinnati Children&#039;s Hospital Medical center, Cincinnati, OH, United States. E-mail: tanya.froehlich@cchmc.org
AN  - 623775100
AU  - Froehlich,
AU  - T.
AU  - E.
AU  - Fogler,
AU  - J.
AU  - Barbaresi,
AU  - W.
AU  - J.
AU  - Elsayed,
AU  - N.
AU  - A.
AU  - Evans,
AU  - S.
AU  - W.
AU  - Chan,
AU  - E.
DA  - October
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/cpt.1192
DP  - Ovid Technologies
KW  - academic achievement
KW  - attention deficit disorder/di [Diagnosis]
KW  - attention deficit disorder/dt [Drug Therapy]
KW  - Boston naming test
KW  - comprehension
KW  - drug effect
KW  - dyslexia/di [Diagnosis]
KW  - dyslexia/dt [Drug Therapy]
KW  - evidence based medicine
KW  - handwriting
KW  - human
KW  - hyperactivity
KW  - impulsiveness
KW  - mathematics
KW  - neuropsychological test
KW  - outcome assessment
KW  - paired associate learning
KW  - priority journal
KW  - reaction time
KW  - reading
KW  - review
KW  - spelling
KW  - systematic review
KW  - treatment response
KW  - visual attention
KW  - working memory
KW  - atomoxetine
KW  - central nervous system agents/dt [Drug Therapy]
KW  - central nervous system agents/pv [Special Situation for Pharmacovigilance]
L1  - internal-pdf://1572997026/Froehlich-2018-Using ADHD Medications to Treat.pdf
LA  - English
M3  - Review
PY  - 2018
SP  - 619-637
T2  - Clinical Pharmacology and Therapeutics
TI  - Using ADHD Medications to Treat Coexisting ADHD and Reading Disorders: A Systematic Review
UR  - http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1532-6535
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=623775100
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1002%2Fcpt.1192&amp;issn=0009-9236&amp;isbn=&amp;volume=104&amp;issue=4&amp;spage=619&amp;pages=619-637&amp;date=2018&amp;title=Clinical+Pharmacology+and+Therapeutics&amp;atitle=Using+ADHD+Medications+to+Treat+Coexisting+ADHD+and+Reading+Disorders%3A+A+Systematic+Review&amp;aulast=Froehlich&amp;pid=%3Cauthor%3EFroehlich+T.E.%3C%2Fauthor%3E%3CAN%3E623775100%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://ascpt.onlinelibrary.wiley.com/doi/abs/10.1002/cpt.1192
VL  - 104
ER  -
TY  - JOUR
AB  - Previous research has indicated that Interpersonal Psychotherapy (IPT) is generally effective for ameliorating symptoms for adults suffering from depression. 

Indeed, this has been demonstrated through numerous clinical and open trials, and further confirmed on a larger degree through several meta-analyses. 

However, no such comprehensive reviews have been conducted exclusively with adolescents, a population for which interpersonal relationships holds immense developmental importance. Therefore, a meta-analysis of the effectiveness of IPT-A, the version of IPT modified to specifically address depression in adolescents, was conducted in the present review. 

A total of ten studies yielding 766 participants were included in the present meta-analysis and analyzed using a standardized mean gain (SMG) effect size. The results indicate that IPT-A was significantly effective at reducing depressive symptoms in adolescents and significantly more effective than control or treatment-as-usual groups in treating depression in adolescents. 

IPT-A yielded an overall effect size (Hedges g) of 1.19, while the aggregate effect size for control/placebo groups was 0.58. Overall, the results of this review suggest that IPT-A holds similar promise for improving adolescent depression as the original version does for adults. 

(PsycINFO Database Record (c) 2018 APA, all rights reserved)
AD  - Mychailyszyn, Matthew P.: mmychailyszyn@towson.edu
AN  - 2018-11316-016
AU  - Mychailyszyn,
AU  - M.
AU  - P.
AU  - Elson,
AU  - D.
AU  - M.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
L1  - internal-pdf://2207912780/Mychailyszyn-2018-Working through the blues_ A.pdf
PY  - 2018
SP  - 123-129
T2  - Children and Youth Services Review
TI  - Working through the blues: A meta-analysis on interpersonal psychotherapy for depressed adolescents (IPT-A)
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2018-11316-016
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2018.02.011&amp;issn=0190-7409&amp;isbn=&amp;volume=87&amp;issue=&amp;spage=123&amp;pages=123-129&amp;date=2018&amp;title=Children+and+Youth+Services+Review&amp;atitle=Working+through+the+blues%3A+A+meta-analysis+on+interpersonal+psychotherapy+for+depressed+adolescents+%28IPT-A%29.&amp;aulast=Mychailyszyn&amp;pid=%3Cauthor%3EMychailyszyn%2C+Matthew+P%3C%2Fauthor%3E%3CAN%3E2018-11316-016%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 87
ER  -
TY  - JOUR
AB  - **Background **
Family therapy is a potential strategy to increase family support for those suffering from perinatal depression. Family therapeutic interventions for this population typically target depressed women and their adult family members to improve family functioning and reduce depressive symptoms. 

**Objective **
This systematic review and meta-analysis is a synthesis of the current evidence on the usefulness of family therapy interventions in the prevention and treatment of perinatal depression and impacts on maternal depressive symptoms and family functioning. 

**Methods **
This study used the Cochrane Collaboration guidelines for systematic reviews and meta-analyses. Six electronic databases were searched for randomized controlled trials and cluster randomized trials. The primary outcomes included maternal depressive symptoms and family functioning. 

**Results **
Seven studies were included in the qualitative and quantitative analyses. Fixed effects models showed statistically significant reductions in depressive symptoms at post-intervention in intervention group mothers. Intervention intensity and level of family involvement moderated intervention impacts on maternal depression. A fixed effects model showed a trend in improving family functioning at post-intervention in intervention group couples. 

**Conclusion **
Although a limited number of controlled trials on family therapeutic interventions for this population exist, the findings show that these types of interventions are effective in both the prevention and treatment of perinatal depression. Recommendations for future research are addressed. 

Copyright &copy; 2018 Cluxton-Keller, Bruce. 
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AN  - 2001933387
AU  - Cluxton-Keller,
AU  - F.
AU  - Bruce,
AU  - M.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0198730
L1  - internal-pdf://1811713849/Cluxton-Keller-2018-Clinical effectiveness of.pdf
PY  - 2018
T2  - PLoS ONE
TI  - Clinical effectiveness of family therapeutic interventions in the prevention and treatment of perinatal depression: A systematic review and meta-analysis
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0198730&amp;type=printable
VL  - 13 (6) (no pagination)
ER  -
TY  - JOUR
AB  - This article presents findings from a meta-analysis of 24 primary research studies on the Second Step social emotional learning program. Program content knowledge, outcomes related to prosociality, and outcomes related to antisociality are examined as outcome categories in randomized controlled trials, quasi-experimental studies and, separately, single-group repeated measures design studies. 

Students participating in Second Step demonstrated increased knowledge of program content and increased prosocial outcomes. Participation in the program was not associated with significant changes in antisocial outcomes. Evidence suggests the possibility of publication bias in studies reporting knowledge outcomes but no evidence of publication bias in studies reporting prosocial and antisocial outcomes. 

This study complements broader meta-analyses on SEL programs and aims to inform local decision making by providing an estimate of the overall effects of the Second Step program on a variety of student outcomes.
AN  - 30463668
AU  - Moy,
AU  - G.
AU  - E.
AU  - Hazen,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jsp.2018.10.006
L1  - internal-pdf://0363725280/Moy-2018-A systematic review of the Second Ste.pdf
PY  - 2018
SP  - 18-41
T2  - Journal of School Psychology
TI  - A systematic review of the Second Step program
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30463668
UR  - https://ac.els-cdn.com/S0022440518301080/1-s2.0-S0022440518301080-main.pdf?_tid=c37649f7-34ec-4263-b77f-1bcaaddff7b4&amp;acdnat=1547554306_8e800045e72aeed5112bfb614a070928
VL  - 71
ER  -
TY  - JOUR
AB  - **Background**
Autism spectrum disorder (ASD) is characterised by significant impairment in social communication and the presence of restrictive and repetitive behaviour or interest. Intervention during early childhood could decrease ASD symptoms. We aimed to identify the most effective intervention based on cognitive, developmental, and behavioural approaches and the factors that impact the effectiveness of the intervention.

**Methods**
We performed a systematic review and meta-analysis of existing interventions for ASD in preschool-aged children. Electronic databases were searched for related articles with randomised controlled trial (RCT) designs published between 2001 to 2015. Outcome measures were communication, behavioural and cognitive skills, reported as standardised mean differences (SMD) compared to a control group. A Random-effects model was utilised to calculate the pooled estimate effect. Between-study variability was also assessed. The registering number of this study is CRD42017035354.

**Findings**
Out of the initial 5174 studies that were identified, there were 14 RCTs (746 children) that were included in the final systematic review and meta-analysis. Pooled estimate effect provided by random-effects model was 0.23 (95% confidence interval, CI [0.08&ndash;0.37]) with no between-study heterogeneity (I2 = 0.00%, p = 0.0018). Three studies of music therapy interventions provided the greatest outcome effects with a shorter duration and lower intensity. SMD for music therapies ranged from 0.40 to 0.62 with 95% CI [0.22 to 1.85]. The quality of the health care provider, the duration, and the intensity of intervention played an important role in the effectiveness of the intervention.

**Interpretation**
Music therapy appears to be an effective tool for improving social interaction in preschool-aged children with ASD. However, more evidence-based trials are required to further validate the effectiveness of music therapy in ASD.
AD  - Su Maw, Su. Graduate School of Health Sciences, Okayama University, Shikata cho, Kita-ku, 700-8558, Okayama city, Japan.Haga, Chiyori. Graduate School of Health Sciences, Okayama University, Shikata cho, Kita-ku, 700-8558, Okayama city, Japan.
AN  - 30211331
AU  - Su
AU  - Maw,
AU  - S.
AU  - Haga,
AU  - C.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.heliyon.2018.e00763
DP  - Ovid Technologies
J2  - Heliyon
L1  - internal-pdf://2809998776/Su Maw-2018-Effectiveness of cognitive, develo.pdf
LA  - English
M3  - Review
N1  - Su Maw, SuHaga, Chiyori
PY  - 2018
SP  - e00763
T2  - Heliyon
TI  - Effectiveness of cognitive, developmental, and behavioural interventions for Autism Spectrum Disorder in preschool-aged children: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30211331
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30211331&amp;id=doi:10.1016%2Fj.heliyon.2018.e00763&amp;issn=2405-8440&amp;isbn=&amp;volume=4&amp;issue=9&amp;spage=e00763&amp;pages=e00763&amp;date=2018&amp;title=Heliyon&amp;atitle=Effectiveness+of+cognitive%2C+developmental%2C+and+behavioural+interventions+for+Autism+Spectrum+Disorder+in+preschool-aged+children%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Su+Maw&amp;pid=%3Cauthor%3ESu+Maw+S%3C%2Fauthor%3E%3CAN%3E30211331%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129682/pdf/main.pdf
VL  - 4
ER  -
TY  - JOUR
AB  - The use of technology in intervention is not uncommon for improving emotion recognition of individuals with autism spectrum disorders (ASD). The purpose of this paper is to examine the effectiveness of technology-based interventions in emotion recognition in people with ASD. 

After searching six electronic databases, 15 studies published from 2000 to 2016 were yielded and reviewed. Eight technology-based interventions for improving emotion recognition skills in people with ASD were identified. 

Overall, this review provides preliminary evidence that the use of technology-based intervention with coach support and emphasis on facial features can improve emotion recognition in children and adolescents with ASD. 

Factors which need to be considered in order to confirm the effectiveness of various intervention programs were discussed.
AD  - [Lee, Clara S. C.; Lam, Stephen H. F.; Tsang, Sally T. K.; Yuen, Cheong M. C.; Ng, Carmen K. M.] Hong Kong Polytech Univ, Dept Rehabil Sci, Hong Kong, Hong Kong, Peoples R China.Lee, CSC (reprint author), Hong Kong Polytech Univ, Dept Rehabil Sci, Hong Kong, Hong Kong, Peoples R China.clara.sc.lee@polyu.edu.hk
AN  - WOS:000432919200001
AU  - Lee,
AU  - C.
AU  - S.
AU  - C.
AU  - Lam,
AU  - S.
AU  - H.
AU  - F.
AU  - Tsang,
AU  - S.
AU  - T.
AU  - K.
AU  - Yuen,
AU  - C.
AU  - M.
AU  - C.
AU  - Ng,
AU  - C.
AU  - K.
AU  - M.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s40489-017-0125-1
J2  - Rev. J. Autism Dev. Disord.
KW  - Autism spectrum disorders
KW  - Emotion recognition
KW  - Technology-based
KW  - Intervention
KW  - high-functioning autism
KW  - randomized controlled-trial
KW  - asperger-syndrome
KW  - normal adults
KW  - children
KW  - asd
KW  - mind
KW  - information
KW  - students
KW  - design
KW  - Psychology
L1  - internal-pdf://0263981260/Lee-2018-The Effectiveness of Technology-Based.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GG8AFTimes Cited: 0Cited Reference Count: 37Lee, Clara S. C. Lam, Stephen H. F. Tsang, Sally T. K. Yuen, Cheong M. C. Ng, Carmen K. M.0Springer heidelbergHeidelberg2195-7185
PY  - 2018
SP  - 91-104
T2  - Review Journal of Autism and Developmental Disorders
TI  - The Effectiveness of Technology-Based Intervention in Improving Emotion Recognition Through Facial Expression in People with Autism Spectrum Disorder: a Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000432919200001
UR  - https://link.springer.com/article/10.1007%2Fs40489-017-0125-1
VL  - 5
ER  -
TY  - JOUR
AB  - The aim of this study is to gather evidence of head-to-head double-blind randomized-controlled trials on the efficacy and safety of available treatments for attention deficit hyperactivity disorder (ADHD) in children and adolescents. A systematic review was conducted by two independent reviewers in ten electronic databases (PROSPERO register CRD42016043239). 

Methodological quality of included studies was evaluated according to the Jadad scale. Network meta-analyses were performed including double-blinded head-to-head trials comparing active allopathic drugs in patients (0-18 years old) diagnosed with ADHD. 

The results of efficacy and safety of atomoxetine (ATX), bupropion, buspirone (BSP), dexamphetamine, edivoxetine (EDX), guanfacine (GXR), lisdexamfetamine (LDX), methylphenidate (MPH), mixed amphetamine salts, modafinil, pindolol (PDL), reboxetine (RBX), selegiline, and venlafaxine were analyzed using ADDIS software v.1.16.5. 

Forty-eight trials were identified (n = 4169 participants), of which 12 were used for efficacy analysis and 33 for safety analysis. On the CGI-I scale, the analysis revealed that MPH was more effective than ATX and GXR. For the safety outcomes, according to drug ranks, LDX was more likely to cause sleep disorders (39%) as well as loss of appetite (65%) and behavior problems such as irritability (60%). BSP (71%) and EDX (44%) caused less appetite decrease. 

For behavioral effects, PDL was considered safest (50%). For any adverse events, RBX (89%) was the safest alternative. The lack of head-to-head trials properly reporting outcomes of interest limited some comparisons. 

Network meta-analysis offered a broader overview on the available treatments for ADHD, especially for safety issues, and contributes towards evidence gathering and clinical practice decisions. A core outcome set for ADHD should be designed to guide the conduction and report of clinical trials.
AN  - 29460165
AU  - Padilha,
AU  - S.
AU  - Virtuoso,
AU  - S.
AU  - Tonin,
AU  - F.
AU  - S.
AU  - Borba,
AU  - H.
AU  - H.
AU  - L.
AU  - Pontarolo,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00787-018-1125-0
L1  - internal-pdf://2026758476/Padilha-2018-Efficacy and safety of drugs for.pdf
PY  - 2018
SP  - 19
T2  - European Child &amp; Adolescent Psychiatry
TI  - Efficacy and safety of drugs for attention deficit hyperactivity disorder in children and adolescents: a network meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29460165
UR  - https://link.springer.com/article/10.1007%2Fs00787-018-1125-0
UR  - https://link.springer.com/content/pdf/10.1007%2Fs00787-018-1125-0.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - Our aim was to investigate whether four treatment features (i.e., the inclusion of parental involvement, goal-setting strategies, maintenance/relapse prevention sessions, the addition of booster sessions) were associated with posttreatment and follow-up effect size of youth cognitive behavioral therapies (yCBTs) for anxiety, depression, posttraumatic stress disorder, and obsessive-compulsive disorder in age groups spanning young children to adolescents. 

We conducted a random-effects meta-analysis of 106 yCBTs tested in 76 randomized clinical trials from the PracticeWise Database to examine average effects of yCBTs posttreatment and at a later follow-up assessment. 

We coded the use of parental involvement, goal setting, booster sessions, and maintenance/relapse prevention in each yCBT and conducted random-effects meta-regression analyses to investigate whether these treatment features were associated with yCBT effects at posttreatment as well as at follow-up. 

Overall, yCBTs produced large pre- to posttreatment effects (d = 1.05), 95% confidence interval [0.94, 1.15], and larger pre- to follow-up effects (d = 1.29), 95% confidence interval [1.18, 1.40]. Metaregression results indicated that parental involvement was significantly associated with larger pre- to posttreatment effect sizes as well as pre- to follow-up effect sizes. 

Booster sessions, goal setting, and maintenance/relapse prevention were not significantly related to effect sizes at posttreatment or follow-up. Parental involvement may be helpful for maximizing long-term effectiveness of yCBT. 

Future studies should investigate for whom and under what conditions inclusion of yCBT treatment features is related to the durability of treatment gains.
AD  - Sun, Michael. a Department of Psychology , University of California , Los Angeles.Rith-Najarian, Leslie R. a Department of Psychology , University of California , Los Angeles.Williamson, Timothy J. a Department of Psychology , University of California , Los Angeles.Chorpita, Bruce F. a Department of Psychology , University of California , Los Angeles.
AN  - 29677451
AU  - Sun,
AU  - M.
AU  - Rith-Najarian,
AU  - L.
AU  - R.
AU  - Williamson,
AU  - T.
AU  - J.
AU  - Chorpita,
AU  - B.
AU  - F.
DA  - Apr 20
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15374416.2018.1443459
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
L1  - internal-pdf://2199528265/Sun-2018-Treatment Features Associated with Yo.pdf
LA  - English
N1  - Sun, MichaelRith-Najarian, Leslie RWilliamson, Timothy JChorpita, Bruce F
PY  - 2018
SP  - 1-15
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Treatment Features Associated with Youth Cognitive Behavioral Therapy Follow-Up Effects for Internalizing Disorders: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29677451
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29677451&amp;id=doi:10.1080%2F15374416.2018.1443459&amp;issn=1537-4416&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-15&amp;date=2018&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Treatment+Features+Associated+with+Youth+Cognitive+Behavioral+Therapy+Follow-Up+Effects+for+Internalizing+Disorders%3A+A+Meta-Analysis.&amp;aulast=Sun&amp;pid=%3Cauthor%3ESun+M%3C%2Fauthor%3E%3CAN%3E29677451%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/pdf/10.1080/15374416.2018.1443459?needAccess=true
ER  -
TY  - JOUR
AB  - **Objectives: **
To assess the efficacy and tolerability of lithium for the treatment of acute mania in children and adolescent diagnosed with bipolar disorder. 

**Methods: **
A systematic literature search up to August 2017 was conducted for clinical trials that included lithium in males and females up to 18 years of age with a diagnosis of bipolar disorder and experiencing a manic or mixed episode according to standardized diagnostic criteria. The protocol was registered in PROSPERO (CRD42017055675). 

**Results: **
Four independent studies described in seven manuscripts met the inclusion criteria. Overall, 176 patients were treated with lithium either as a monotherapy or adjunct to risperidone. Efficacy results suggest that lithium may be superior to placebo (standardized mean difference [SMD] -0.42, 95% confidence interval [CI] -0.88 to 0.04), comparable to sodium divalproex (SMD -0.07, 95% CI: -0.31 to 0.18), but significantly less effective than risperidone for treating protracted manic/mixed episodes and comorbid attention-deficit hyperactivity disorder (ADHD) in prepubertal children (SMD 0.85, 95% CI: 0.54 to 1.15). Lithium was not associated with serious adverse events, and was generally well tolerated with common side effects similar to those reported in adults. 

**Conclusions: **
Limited data suggests that lithium may be an effective and tolerable treatment for some forms of paediatric mania. However, lithium is clearly inferior in efficacy to risperidone in prepubertal patients diagnosed with protracted manic/mixed episodes and comorbid ADHD. There is a lack of data concerning the efficacy and tolerability of lithium as an acute treatment for classical mania in adolescents and important clinical issues remain unaddressed. 

Copyright &copy; 2018 John Wiley &amp; Sons A/S. Published by John Wiley &amp; Sons Ltd
AD  - (Duffy) Department of Psychiatry, Queen&#039;s University, Kingston, ON, Canada (Heffer, Cipriani) University of Oxford, Oxford, United Kingdom (Goodday) Department of Epidemiology, University of Toronto, Toronto, ON, Canada (Weir) Mood Disorders Centre of Ottawa, Ottawa, ON, Canada (Patten) University of Calgary Cumming School of Medicine, Calgary, AB, Canada (Malhi) The University of Sydney School of Medicine, Sydney, AustraliaA. Duffy, Department of Psychiatry, Queen&#039;s University, Kingston, ON, Canada. E-mail: anne.duffy@queensu.ca
AN  - 623948390
AU  - Duffy,
AU  - A.
AU  - Heffer,
AU  - N.
AU  - Goodday,
AU  - S.
AU  - M.
AU  - Weir,
AU  - A.
AU  - Patten,
AU  - S.
AU  - Malhi,
AU  - G.
AU  - S.
AU  - Cipriani,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/bdi.12690
DP  - Ovid Technologies
KW  - adolescents
KW  - bipolar disorder
KW  - children
KW  - efficacy
KW  - lithium
KW  - mania
KW  - manic episode
KW  - meta-analysis
KW  - systematic review
KW  - tolerability
KW  - treatment
KW  - adolescent
KW  - adult
KW  - adverse event
KW  - article
KW  - attention deficit disorder
KW  - child
KW  - clinical trial (topic)
KW  - diagnosis
KW  - drug efficacy
KW  - drug therapy
KW  - female
KW  - human
KW  - joint
KW  - male
KW  - mixed mania and depression
KW  - monotherapy
KW  - publication
KW  - side effect
KW  - placebo
KW  - risperidone
L1  - internal-pdf://2614363753/Duffy-2018-Efficacy and tolerability of lithiu.pdf
LA  - English
M3  - In Press
N1  - Using Smart Source ParsingDate of Publication: 2018
PY  - 2018
T2  - Bipolar Disorders.
TI  - Efficacy and tolerability of lithium for the treatment of acute mania in children with bipolar disorder: A systematic review: A report from the ISBD-IGSLi joint task force on lithium treatment
UR  - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1399-5618
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=623948390
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1111%2Fbdi.12690&amp;issn=1398-5647&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Bipolar+Disorders&amp;atitle=Efficacy+and+tolerability+of+lithium+for+the+treatment+of+acute+mania+in+children+with+bipolar+disorder%3A+A+systematic+review%3A+A+report+from+the+ISBD-IGSLi+joint+task+force+on+lithium+treatment&amp;aulast=Duffy&amp;pid=%3Cauthor%3EDuffy+A.%3C%2Fauthor%3E%3CAN%3E623948390%3C%2FAN%3E%3CDT%3EArticle+In+Press%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/bdi.12690
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Substance abuse has been prevalent among caregivers involved in child welfare and is a major barrier to their achieving favorable outcomes. Family Treatment Drug Courts (FTDCs) have been viewed as one of the most promising interventions but research has reported mixed effects on child welfare outcomes. No meta-analysis was conducted to synthesize the findings to reach a more generalizable conclusion.

**OBJECTIVE:** 
The meta-analysis synthesized findings from existing evaluations to examine whether and to what extent FTDC participants achieved better reunification and safety outcomes than non-participants.

**PARTICIPANTS AND SETTING:** 
Among 17 identified studies dated from 2004 to 2018, the pooled sample subjects in the intervention and comparison groups were 3402 and 3683 for the 16 studies on reunification outcomes, and 842 and 632 for the eight studies on child safety outcomes.

**METHODS:** 
We first estimated the FTDCs&#039; pooled effects on child reunification and safety outcomes. Furthermore, we conducted a series of subgroup meta-analysis to compare FTDCs&#039; effects across study and program characteristics.

**RESULTS:** 
Subjects participating in FTDCs were substantially more likely to achieve reunification (OR = 1.75, 95% CI = 1.38, 2.22) without increasing the risk of subsequent foster care reentry or maltreatment re-report. Subgroup meta-analysis suggests factors such as research design, FTDC model, observation length, publication type and period may contribute to FTDCs&#039; disparities on reunification outcomes.

**CONCLUSIONS:** 
The synthesized findings strengthen evidence for the implementation and expansion of FTDCs for serving substance abusing caregivers in the child welfare system.
AD  - Zhang, Saijun. Department of Social Work, University of Mississippi, Longstreet Hall 303 University, MS 38677, United States. Electronic address: szhang9@olemiss.edu.Huang, Hui. Robert Stempel College of Public Health &amp; Social Work, United States. Electronic address: huanhu@fiu.edu.Wu, Qi. School of Social Work, Arizona State University, United States. Electronic address: Qi.Wu.5@asu.edu.Li, Yong. Department of Social Work, California State University Bakersfield, United States. Electronic address: yli12@csub.edu.Liu, Meirong. School of Social Work, Howard University, United States. Electronic address: meirong.liu@howard.edu.
AN  - 30412783
AU  - Zhang,
AU  - S.
AU  - Huang,
AU  - H.
AU  - Wu,
AU  - Q.
AU  - Li,
AU  - Y.
AU  - Liu,
AU  - M.
DA  - Nov 06
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.chiabu.2018.10.014
DP  - Ovid Technologies
J2  - Child Abuse Negl
L1  - internal-pdf://1981977052/Zhang-2018-The impacts of family treatment dru.pdf
LA  - English
N1  - Zhang, SaijunHuang, HuiWu, QiLi, YongLiu, MeirongS0145-2134(18)30402-2
PY  - 2018
SP  - 1-14
T2  - Child Abuse &amp; Neglect
TI  - The impacts of family treatment drug court on child welfare core outcomes: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30412783
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30412783&amp;id=doi:10.1016%2Fj.chiabu.2018.10.014&amp;issn=0145-2134&amp;isbn=&amp;volume=88&amp;issue=&amp;spage=1&amp;pages=1-14&amp;date=2018&amp;title=Child+Abuse+%26+Neglect&amp;atitle=The+impacts+of+family+treatment+drug+court+on+child+welfare+core+outcomes%3A+A+meta-analysis.&amp;aulast=Zhang&amp;pid=%3Cauthor%3EZhang+S%3C%2Fauthor%3E%3CAN%3E30412783%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S0145213418304022/1-s2.0-S0145213418304022-main.pdf?_tid=61ea5f37-5b03-4130-b5af-4986ecd98c9f&amp;acdnat=1544796621_f5bf14be114fd78a5ee67106e32980f4
VL  - 88
ER  -
TY  - JOUR
AB  - This study evaluated the effectiveness of Incredible Years (IY) programs for Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 3 to 8 years based on a systematic literature review. Effects of IY programs for children with or at risk for ADHD are examined in addition to the impact on ADHD behaviors in young children identified as having conduct problems or disruptive behavior. Search strategies identified 17 publications reflecting 11 unique intervention studies, including three with samples demonstrating elevated ADHD symptoms or meeting criteria for ADHD. Effects on ADHD outcomes, primarily parent report, were positive and comparable to those seen for conduct problems; benefits were also seen on social skills. Smaller and more variable effects were seen on observational measures and teacher reports. The overall methodological strength of this literature was relatively strong, although lack of fidelity measurement is a weakness. Using criteria established by the American Psychological Association&#039;s Division 53 (Society of Clinical Child and Adolescent Psychology), the IY Basic Parent Program may be considered Probably Efficacious for young children at risk for ADHD. In addition, the combined IY parent and child treatment programs can be considered Possibly Efficacious for children aged 4 to 6 years with ADHD, based on one study by the developer with a diagnosed sample. (PsycINFO Database Record (c) 2020 APA, all rights reserved)
AD  - Murray, Desiree W.: desiree.murray@unc.eduMurray, Desiree W.: Frank Porter Graham Child Development Institute, University of North Carolina at Chapel Hill, Campus Box 8180, 105 Smith Level Road, Chapel Hill, NC, US, 27599-8180, desiree.murray@unc.eduMurray, Desiree W.: University of North Carolina at Chapel Hill, Chapel Hill, NC, USLawrence, Jacqueline R.: University of North Carolina at Chapel Hill, Chapel Hill, NC, USLaForett, Dore R.: University of North Carolina at Chapel Hill, Chapel Hill, NC, US
AN  - 2018-58354-001
AU  - Murray,
AU  - Desiree
AU  - W.
AU  - Lawrence,
AU  - Jacqueline
AU  - R.
AU  - LaForett,
AU  - Dore
AU  - R.
DA  - Dec
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1177/1063426617717740
DP  - Ovid Technologies
KW  - ADD/ADHD, disorders/disabilities, behavioral, interventions, child, interventions, effectiveness, programs/practices
KW  - *Attention Deficit Disorder with Hyperactivity
KW  - *Behavior Problems
KW  - *Child Psychopathology
KW  - *Mental Health Program Evaluation
KW  - *Parent Report
KW  - At Risk Populations
KW  - Social Skills
KW  - Treatment Effectiveness Evaluation
KW  - Developmental Disorders &amp; Autism [3250]
KW  - Human Childhood (birth-12 yrs) School Age (6-12 yrs)
L1  - internal-pdf://0997988916/Murray-2018-The Incredible Years programs for.pdf
LA  - English
M3  - Literature Review
PY  - 2018
SP  - 195-208
T2  - Journal of Emotional and Behavioral Disorders
TI  - The Incredible Years programs for ADHD in young children: A critical review of the evidence
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2018-58354-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1063426617717740&amp;issn=1063-4266&amp;isbn=&amp;volume=26&amp;issue=4&amp;spage=195&amp;pages=195-208&amp;date=2018&amp;title=Journal+of+Emotional+and+Behavioral+Disorders&amp;atitle=The+Incredible+Years+programs+for+ADHD+in+young+children%3A+A+critical+review+of+the+evidence.&amp;aulast=Murray&amp;pid=%3Cauthor%3EMurray%2C+Desiree+W%3C%2Fauthor%3E%3CAN%3E2018-58354-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://journals.sagepub.com/doi/pdf/10.1177/1063426617717740
VL  - 26
ER  -
TY  - JOUR
AB  - Meditation-based interventions such as mindfulness and yoga are commonly practiced in the general community to improve mental and physical health. 

Parents, teachers and healthcare providers are also increasingly using such interventions with children. This review examines the use of meditation-based interventions in the treatment of children with Attention-Deficit Hyperactivity Disorder (ADHD). 

Electronic databases searched included PsycINFO, Medline, CINAHL, and AMED. Inclusion criteria involved children (aged to 18 years) diagnosed with ADHD, delivery of a meditation-based intervention to children and/or parents, and publication in a peer-reviewed journal. Studies were identified and coded using standard criteria, risk of bias was assessed using Risk of Bias in Non-randomised Studies- of interventions (ROBINS-I), and effect sizes were calculated. 

A total of 16 studies were identified (8 that included children in treatment, and 8 that included combined parent-child treatment). Results indicated that risk of bias was high across studies. At this stage, no definitive conclusions can be offered regarding the utility of meditation-based interventions for children with ADHD and/or their parents, since the methodological quality of the studies reviewed is low. 

Future well designed research is needed to establish the efficacy of meditation-based interventions, including commonly used practices such as mindfulness, before recommendations can be made for children with ADHD and their families. 

Copyright &copy; 2017, Springer-Verlag Berlin Heidelberg.
AU  - Evans,
AU  - S.
AU  - Ling,
AU  - M.
AU  - Hill,
AU  - B.
AU  - Rinehart,
AU  - N.
AU  - Austin,
AU  - D.
AU  - Sciberras,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00787-017-1008-9
L1  - internal-pdf://3765232839/Evans-2018-Systematic review of meditation-bas.pdf
PY  - 2018
SP  - 9-27
T2  - European Child and Adolescent Psychiatry
TI  - Systematic review of meditation-based interventions for children with ADHD
UR  - http://www.springerlink.com/content/1018-8827
UR  - https://link.springer.com/article/10.1007%2Fs00787-017-1008-9
UR  - https://link.springer.com/content/pdf/10.1007%2Fs00787-017-1008-9.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - Omega-3 supplements are considered to have anti-inflammatory effects which may be beneficial as inflammation has been linked to ADHD. The aim of this review is to examine the effectiveness of omega-3 supplementation at reducing ADHD symptoms in children and adolescents. Medline, Cinahl+, PsycINFO, Cochrane and Embase were searched for trials investigating the effects of omega-3 supplementation in children and adolescents with ADHD. The primary outcome measure was a mean difference in Conners&#039; rating scale (CRS) between the intervention and placebo group. Search terms used include ADHD, omega-3, fish oils, eicosapentaenoic acid, docosahexaenoic acids, alpha-linolenic acid and Conners&#039; rating scale. Randomized controlled trials examining the efficacy of omega-3 supplementation in children and adolescents as measured by CRS were included. Studies using a combination of polyunsaturated fatty acids or any other rating scale were excluded. Seven trials were included in this review, totalling 926 participants. We found no evidence of publication bias or heterogeneity between trials. Overall, there was a slightly greater reduction in CRS score in favour of the experiment group. One study found a greater reduction in score in favour of the placebo group. Neither findings were statistically significant. There is little supportive evidence to validate the claim of omega-3 supplementation to reduce the degree of ADHD symptoms experienced by children and adolescents. Both experiment and control groups saw similar reductions in Conners rating scale score.
AN  - 30594823
AU  - Abdullah,
AU  - M.
AU  - Jowett,
AU  - B.
AU  - Whittaker,
AU  - P.
AU  - J.
AU  - Patterson,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jpsychires.2018.12.002
L1  - internal-pdf://3928533214/Abdullah-2018-The effectiveness of omega-3 sup.pdf
PY  - 2018
SP  - 64-73
T2  - Journal of Psychiatric Research
TI  - The effectiveness of omega-3 supplementation in reducing ADHD associated symptoms in children as measured by the Conners&#039; rating scales: A systematic review of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30594823
UR  - https://ac.els-cdn.com/S0022395618310185/1-s2.0-S0022395618310185-main.pdf?_tid=e7b104e1-62a6-453b-a923-7e4e484bceef&amp;acdnat=1549447243_4fb3ff04aa0b3446f6e891763a360ced
VL  - 110
ER  -
TY  - JOUR
AB  - **Background**
Lone parents in high‐income countries have high rates of poverty (including in‐work poverty) and poor health. Employment requirements for these parents are increasingly common. &#039;Welfare‐to‐work&#039; (WtW) interventions involving financial sanctions and incentives, training, childcare subsidies and lifetime limits on benefit receipt have been used to support or mandate employment among lone parents. These and other interventions that affect employment and income may also affect people&#039;s health, and it is important to understand the available evidence on these effects in lone parents.

**Objectives**
To assess the effects of WtW interventions on mental and physical health in lone parents and their children living in high‐income countries. The secondary objective is to assess the effects of welfare‐to‐work interventions on employment and income.

**Search methods**
We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE Ovid, Embase Ovid, PsycINFO EBSCO, ERIC EBSCO, SocINDEX EBSCO, CINAHL EBSCO, Econlit EBSCO, Web of Science ISI, Applied Social Sciences Index and Abstracts (ASSIA) via Proquest, International Bibliography of the Social Sciences (IBSS) via ProQuest, Social Services Abstracts via Proquest, Sociological Abstracts via Proquest, Campbell Library, NHS Economic Evaluation Database (NHS EED) (CRD York), Turning Research into Practice (TRIP), OpenGrey and Planex. We also searched bibliographies of included publications and relevant reviews, in addition to many relevant websites. We identified many included publications by handsearching. We performed the searches in 2011, 2013 and April 2016.

**Selection criteria**
Randomised controlled trials (RCTs) of mandatory or voluntary WtW interventions for lone parents in high‐income countries, reporting impacts on parental mental health, parental physical health, child mental health or child physical health.

**Data collection and analysis**
One review author extracted data using a standardised extraction form, and another checked them. Two authors independently assessed risk of bias and the quality of the evidence. We contacted study authors to obtain measures of variance and conducted meta‐analyses where possible. We synthesised data at three time points: 18 to 24 months (T1), 25 to 48 months (T2) and 49 to 72 months (T3).

**Main results**
Twelve studies involving 27,482 participants met the inclusion criteria. Interventions were either mandatory or voluntary and included up to 10 discrete components in varying combinations. All but one study took place in North America. Although we searched for parental health outcomes, the vast majority of the sample in all included studies were female. Therefore, we describe adult health outcomes as &#039;maternal&#039; throughout the results section. We downgraded the quality of all evidence at least one level because outcome assessors were not blinded. Follow‐up ranged from 18 months to six years. The effects of welfare‐to‐work interventions on health were generally positive but of a magnitude unlikely to have any tangible effects.

At T1 there was moderate‐quality evidence of a very small negative impact on maternal mental health (standardised mean difference (SMD) 0.07, 95% Confidence Interval (CI) 0.00 to 0.14; N = 3352; studies = 2)); at T2, moderate‐quality evidence of no effect (SMD 0.00, 95% CI 0.05 to 0.05; N = 7091; studies = 3); and at T3, low‐quality evidence of a very small positive effect (SMD &minus;0.07, 95% CI &minus;0.15 to 0.00; N = 8873; studies = 4). There was evidence of very small positive effects on maternal physical health at T1 (risk ratio (RR) 0.85, 95% CI 0.54 to 1.36; N = 311; 1 study, low quality) and T2 (RR 1.06, 95% CI 0.95 to 1.18; N = 2551; 2 studies, moderate quality), and of a very small negative effect at T3 (RR 0.97, 95% CI 0.91 to 1.04; N = 1854; 1 study, low quality).

At T1, there was moderate‐quality evidence of a very small negative impact on child mental health (SMD 0.01, 95% CI &minus;0.06 to 0.09; N = 2762; studies = 1); at T2, of a very small positive effect (SMD &minus;0.04, 95% CI &minus;0.08 to 0.01; N = 7560; studies = 5), and at T3, there was low‐quality evidence of a very small positive effect (SMD &minus;0.05, 95% CI &minus;0.16 to 0.05; N = 3643; studies = 3). Moderate‐quality evidence for effects on child physical health showed a very small negative effect at T1 (SMD &minus;0.05, 95% CI &minus;0.12 to 0.03; N = 2762; studies = 1), a very small positive effect at T2 (SMD 0.07, 95% CI 0.01 to 0.12; N = 7195; studies = 3), and a very small positive effect at T3 (SMD 0.01, 95% CI &minus;0.04 to 0.06; N = 8083; studies = 5). There was some evidence of larger negative effects on health, but this was of low or very low quality.

There were small positive effects on employment and income at 18 to 48 months (moderate‐quality evidence), but these were largely absent at 49 to 72 months (very low to moderate‐quality evidence), often due to control group members moving into work independently. Since the majority of the studies were conducted in North America before the year 2000, generalisabilty may be limited. However, all study sites were similar in that they were high‐income countries with developed social welfare systems.

**Authors&#039; conclusions**
The effects of WtW on health are largely of a magnitude that is unlikely to have tangible impacts. Since income and employment are hypothesised to mediate effects on health, it is possible that these negligible health impacts result from the small effects on economic outcomes. Even where employment and income were higher for the lone parents in WtW, poverty was still high for the majority of the lone parents in many of the studies. Perhaps because of this, depression also remained very high for lone parents whether they were in WtW or not. There is a lack of robust evidence on the health effects of WtW for lone parents outside North America.
AD  - [Gibson, Marcia; Thomson, Hilary; PMartin, Susan] Univ Glasgow, MRC CSO Social &amp; Publ Hlth Sci Unit, 200 Renfield St, Glasgow G2 3QB, Lanark, Scotland. [Banas, Kasia] Univ Edinburgh, Dept Psychol, Edinburgh, Midlothian, Scotland. [Lutje, Vittoria] Univ Liverpool Liverpool Sch Trop Med, Dept Clin Sci, Liverpool, Merseyside, England. [McKee, Martin J.] Social Value Lab, Glasgow, Lanark, Scotland. [Fenton, Candida] Univ Edinburgh, Usher Inst Populat Hlth Sci &amp; Informat, Edinburgh, Midlothian, Scotland. [Bambra, Clare] Newcastle Univ, Sch Med, Inst Hlth &amp; Soc, Newcastle Upon Tyne, Tyne &amp; Wear, England. [Bond, Lyndal] Victoria Univ, Coll Hlth &amp; Biomed, Melbourne, Vic, Australia.Gibson, M (reprint author), Univ Glasgow, MRC CSO Social &amp; Publ Hlth Sci Unit, 200 Renfield St, Glasgow G2 3QB, Lanark, Scotland.marcia.gibson@glasgow.ac.uk
AN  - WOS:000426476500003
AU  - Gibson,
AU  - M.
AU  - Thomson,
AU  - H.
AU  - Banas,
AU  - K.
AU  - Lutje,
AU  - V.
AU  - McKee,
AU  - M.
AU  - J.
AU  - Pmartin,
AU  - S.
AU  - Fenton,
AU  - C.
AU  - Bambra,
AU  - C.
AU  - Bond,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009820.pub3
J2  - Cochrane Database Syst Rev.
KW  - *Child Health [ethics]
KW  - *Health Status
KW  - *Maternal Health [ethics]
KW  - *Mental Health
KW  - Employment [economics
KW  - ethics
KW  - legislation &amp;
KW  - jurisprudence
KW  - *psychology]
KW  - Income
KW  - Insurance, Health [statistics &amp;
KW  - numerical data]
KW  - Poverty
KW  - Randomized Controlled Trials as Topic
KW  - Single
KW  - Parent [*psychology]
KW  - Social Welfare [ethics
KW  - legislation &amp;
KW  - jurisprudence
KW  - *psychology]
KW  - self-sufficiency project
KW  - low-income families
KW  - single mothers
KW  - public-health
KW  - advancement demonstration
KW  - employment retention
KW  - social
KW  - interventions
KW  - systematic reviews
KW  - subgroup analysis
KW  - middle-childhood
KW  - General &amp; Internal Medicine
L1  - internal-pdf://0000850876/Gibson-2018-Welfare-to-work interventions and.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: FY0CCTimes Cited: 0Cited Reference Count: 247Gibson, Marcia Thomson, Hilary Banas, Kasia Lutje, Vittoria McKee, Martin J. PMartin, Susan Fenton, Candida Bambra, Clare Bond, LyndalBambra, Clare/0000-0002-1294-6851Chief Scientist Office, Scottish Government Health and Social Care Directorates, UK; UK Medical Research Council/Chief Scientist Office, UK; [MC.UU.12017/4]; [MC.UU.12017-15]; [CZG/2/422]Internal sources; Chief Scientist Office, Scottish Government Health and Social Care Directorates, UK.; Core funding to Evaluating the Health Effects of Social Interventions Programme, MC.UU.12017/4 (to June 2015); UK Medical Research Council/Chief Scientist Office, UK.; Core funding to Informing Healthy Public Policy Programme, MC.UU.12017-15 (from June 2015); External sources; Chief Scientist Office, Scottish Government Health and Social Care Directorates, UK.; Grant code CZG/2/422: Grant funding to (sic)50,00001WileyHoboken1361-6137
PY  - 2018
SP  - 203
T2  - Cochrane Database of Systematic Reviews
TI  - Welfare-to-work interventions and their effects on the mental and physical health of lone parents and their children
UR  - &lt;Go to ISI&gt;://WOS:000426476500003
UR  - http://cochranelibrary-wiley.com/store/10.1002/14651858.CD009820.pub3/asset/CD009820.pdf?v=1&amp;t=jkcmkjry&amp;s=f75dce6e720deddceec118993511a0b5ef511328
ER  -
TY  - JOUR
AB  - **Aim**
To describe existing evidence on non‐pharmacological interventions to manage sleep disturbance in children with neurodisabilities.

**Method**
We systematically reviewed non‐pharmacological interventions aimed at improving non‐respiratory sleep disturbance in children with neurodisability. Sixteen databases, grey literature, and reference lists of included papers were searched up to February 2017. Two researchers (B.B., C.M., G.S., A.S., A.P.) undertook screening, data extraction, and quality appraisal.

**Results**
Twenty‐five studies were included: 11 randomized controlled trials and 14 before‐and‐after studies. All studies were at high or unclear risk of bias. Parent‐directed interventions were categorized as comprehensive tailored interventions (n=9), comprehensive non‐tailored interventions (n=8), and non‐comprehensive interventions (n=2). Six &lsquo;other&rsquo; non‐pharmacological interventions were included. Seventy‐one child and parent sleep‐related outcomes were measured across the included studies. We report the two most commonly measured outcomes: the Child Sleep Habits Questionnaire and sleep onset latency. Five studies reported significant improvements on at least one of these outcomes.

**Interpretation**
Various types of non‐pharmacological intervention for managing sleep disturbance have been evaluated. Clinical heterogeneity and poor study quality meant we could not draw definitive conclusions on the effectiveness of these interventions. Current clinical guidance recommends parent‐directed interventions as the first approach to managing sleep disturbance; prioritizing research in this area is recommended.
AD  - [Scantlebury, Arabella; Spiers, Gemma] Newcastle Univ, Inst Hlth &amp; Soc, Newcastle Upon Tyne, Tyne &amp; Wear, England. [Mcdaid, Catriona; Fairhurst, Caroline; Hewitt, Catherine; Parker, Adwoa] Univ York, Dept Hlth Sci, York Trials Unit, York, N Yorkshire, England. [Dawson, Vicki] Childrens Sleep Char, Doncaster, England. [Elphick, Heather] Sheffield Childrens NHS Fdn Trust, Sheffield, S Yorkshire, England. [Thomas, Megan] Blackpool Teaching Hosp NHS Fdn Trust, Blackpool, England. [Wright, Kath] Univ York, Ctr Reviews &amp; Disseminat, York, N Yorkshire, England. [Beresford, Bryony] Univ York, Social Policy Res Unit, York YO10 5DD, N Yorkshire, England.Beresford, B (reprint author), Univ York, Social Policy Res Unit, York YO10 5DD, N Yorkshire, England.bryony.beresford@york.ac.uk
AN  - WOS:000446560300011
AU  - Scantlebury,
AU  - A.
AU  - McDaid,
AU  - C.
AU  - Dawson,
AU  - V.
AU  - Elphick,
AU  - H.
AU  - Fairhurst,
AU  - C.
AU  - Hewitt,
AU  - C.
AU  - Parker,
AU  - A.
AU  - Spiers,
AU  - G.
AU  - Thomas,
AU  - M.
AU  - Wright,
AU  - K.
AU  - Beresford,
AU  - B.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/dmcn.13972
J2  - Dev. Med. Child Neurol.
KW  - autism spectrum disorders
KW  - randomized controlled-trial
KW  - deficit
KW  - hyperactivity disorder
KW  - attention-deficit/hyperactivity disorder
KW  - challenging daytime behavior
KW  - severe learning-disabilities
KW  - school-aged
KW  - children
KW  - developmental-disabilities
KW  - intellectual disabilities
KW  - management intervention
KW  - Neurosciences &amp; Neurology
KW  - Pediatrics
L1  - internal-pdf://2502405831/Scantlebury-2018-Non-pharmacological intervent.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GW0MCTimes Cited: 0Cited Reference Count: 75Scantlebury, Arabella Mcdaid, Catriona Dawson, Vicki Elphick, Heather Fairhurst, Caroline Hewitt, Catherine Parker, Adwoa Spiers, Gemma Thomas, Megan Wright, Kath Beresford, BryonySpiers, Gemma Frances/0000-0003-2121-4529; Parker, Adwoa/0000-0002-2880-3935; Scantlebury, Arabella/0000-0003-3518-2740NIHR HTA Programme [14/212/02]We thank our parent advisers for their contribution throughout the project. We also thank Kate Baxter for her contribution to the quality appraisal work and Katherine Chatterton for her assistance with sourcing full-text articles. The project was funded by the NIHR HTA Programme (project number 14/212/02). Further information is available at https://www.journalslibrary.nihr.ac.uk/programmes/hta/1421202/#/. BB and MT were authors on primary studies included in the review. CMcD is a member of the NIHR HTA and Efficacy and Medical Evaluation Editorial Board. CH is a member of HTA Commissioning Board. All other authors have stated that they had no interest that could be perceived as posing a conflict or bias.03WileyHoboken1469-8749
PY  - 2018
SP  - 1076-1092
T2  - Developmental Medicine and Child Neurology
TI  - Non-pharmacological interventions for non-respiratory sleep disturbance in children with neurodisabilities: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000446560300011
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/dmcn.13972
VL  - 60
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
Preterm infants are born with low glycogen stores and require higher glucose intake to match fetal accretion rates. In spite of the myriad benefits of breast milk for preterm infants, it may not adequately meet the needs of these rapidly growing infants. Supplementing human milk with carbohydrates may help. However, there is a paucity of data on assessment of benefits or harms of carbohydrate supplementation of human milk to promote growth in preterm infants. This is a 2018 update of a Cochrane Review first published in 1999.

**OBJECTIVES:**
To determine whether human milk supplemented with carbohydrate compared with unsupplemented human milk fed to preterm infants improves growth, body composition, and cardio-metabolic and neurodevelopmental outcomes without significant adverse effects.

**SEARCH METHODS:**
We used the standard search strategy of the Cochrane Neonatal Review Group to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2017, Issue 8), MEDLINE via PubMed (1966 to 21 February 2018), Embase (1980 to 21 February 2018), and the Cumulative Index to Nursing and Allied Health Literature (CINAHL; 1982 to 21 February 2018). We also searched clinical trials databases, conference proceedings, and reference lists of retrieved articles for randomised controlled trials (RCTs) and quasi-randomised trials.

**SELECTION CRITERIA:**
Published and unpublished controlled trials were eligible if they used random or quasi-random methods to allocate preterm infants in hospital fed human milk to supplementation or no supplementation with additional carbohydrate.

**DATA COLLECTION AND ANALYSIS:**
Two review authors independently abstracted data and assessed trial quality and the quality of evidence at the outcome level using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) method. We planned to perform meta-analyses using risk ratios (RRs) for dichotomous data and mean differences (MDs) for continuous data, with their respective 95% confidence intervals (CIs). We planned to use a fixed-effect model and to explore potential causes of heterogeneity via sensitivity analyses. We contacted study authors for additional information.

**MAIN RESULTS:**
One unblinded, quasi-randomised controlled trial (RCT) assessing effects of carbohydrate supplementation of human milk in the form of a prebiotic in 75 preterm infants was eligible for inclusion in this review. We identified two publications of the same trial, which reported different methods regarding blinding and randomisation. Study authors confirmed that these publications pertain to the same trial, but they have not yet clarified which method is correct. We were unable to reproduce analyses from the data presented. At 30 days of age, the mean weight of preterm infants in the trial was greater in the prebiotic carbohydrate-supplemented group than in the unsupplemented group (MD 160.4 grams, 95% CI 12.4 to 308.4 grams; one RCT, N = 75; very low-quality evidence). We found no evidence of a clear difference in risk of feeding intolerance (RR 0.64, 95% CI 0.36 to 1.15; one RCT, N = 75 infants; very low-quality evidence) or necrotising enterocolitis (NEC) (RR 0.2, 95% CI 0.02 to 1.3; one RCT, N = 75 infants; very low-quality evidence) between the prebiotic-supplemented group and the unsupplemented group. Duration of hospital stay was shorter in the prebiotic group than in the control group at a median (range) of 16 (9 to 45) days (95% CI 15.34 to 24.09) and 25 (11 to 80) days (95% CI 25.52 to 34.39), respectively. No other data were available for assessing effects of carbohydrate supplementation on short- and long-term growth, body mass index, body composition, and neurodevelopmental or cardio-metabolic outcomes.

**AUTHORS&#039; CONCLUSIONS:**
We found insufficient evidence on the short- and long-term effects of carbohydrate supplementation of human milk in preterm infants. The only trial included in this review presented very low-quality evidence, and study authors provided uncertain information about study methods and analysis. The evidence may be limited in its applicability because researchers included a small sample of preterm infants from a single centre. However, the outcomes assessed are common to all preterm infants, and this trial demonstrates the feasibility of prebiotic carbohydrate supplementation in upper-middle-income countries. Future trials should assess the safety and efficacy of different types and concentrations of carbohydrate supplementation for preterm infants fed human milk. Although prebiotic carbohydrate supplementation in preterm infants is currently a topic of active research, we do not envisage that further trials of digestible carbohydrates will be conducted, as this is currently done as a component of multi-nutrient human milk fortification. Hence we do not plan to publish any further updates of this review.
AU  - Amissah,
AU  - E.
AU  - A.
AU  - Brown,
AU  - J.
AU  - Harding,
AU  - J.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD000280.pub2.
L1  - internal-pdf://3307982250/Amissah-2018-Carbohydrate supplementation of h.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Carbohydrate supplementation of human milk to promote growth in preterm infants
ER  -
TY  - JOUR
AB  - **Objectives. **
We aimed to summarize and critically evaluate the available evidence regarding the efficacy and safety of acupuncture for children with autism spectrum disorder (ASD). 

**Methods. **
We searched 13 databases for studies published up to December 2016. Randomized controlled trials (RCTs) evaluating the efficacy of acupuncture for children with ASD were included. Outcome measures were the overall scores on scales evaluating the core symptoms of ASD and the scores for each symptom, such as social communication ability and skills, stereotypies, language ability, and cognitive function. Effect sizes were presented as mean differences (MD). 

**Results. **
Twenty-seven RCTs with 1736 participants were included. Acupuncture complementary to behavioral and educational intervention significantly decreased the overall scores on the Childhood Autism Rating Scale (CARS) (MD -8.10, 95% CI -12.80 to -3.40) and the Autism Behavior Checklist (MD -8.92, 95% CI -11.29 to -6.54); however, it was unclear which of the ASD symptoms improved. Acupuncture as a monotherapy also reduced the overall CARS score. The reported adverse events were acceptable. 

**Conclusions. **
This review suggests that acupuncture may be effective and safe for pediatric ASD. However, it is not conclusive due to the heterogeneity of the acupuncture treatment methods used in the studies.
AN  - WOS:000423017900001
AU  - Lee,
AU  - B.
AU  - Lee,
AU  - J.
AU  - Cheon,
AU  - J.
AU  - H.
AU  - Sung,
AU  - H.
AU  - K.
AU  - Cho,
AU  - S.
AU  - H.
AU  - Chang,
AU  - G.
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1155/2018/1057539
L1  - internal-pdf://0247699627/Lee-2018-The Efficacy and Safety of Acupunctur.pdf
PY  - 2018
SP  - 21
T2  - Evidence-Based Complementary and Alternative Medicine
TI  - The Efficacy and Safety of Acupuncture for the Treatment of Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000423017900001
UR  - http://downloads.hindawi.com/journals/ecam/2018/1057539.pdf
ER  -
TY  - JOUR
AB  - This systematic literature review examines single-case intervention research targeting academic and related skills for children with autism spectrum disorder (ASD) in school settings. 

Fifty-four studies published between 1995 and 2014 met inclusion criteria. Tau-U was calculated for each study to examine the effectiveness of interventions. 

The mean score across all the studies was high (M Tau-U=0.78), but ranged from weak to very high with scores between 0.15 and 1.00. The analysis demonstrated that school-based interventions were generally effective at improving the academic and related skills of students with ASD. 

The authors summarized some critical gaps in the research, and reviewed the quality of the research designs.
AN  - WOS:000452079900001
AU  - Alresheed,
AU  - F.
AU  - Machalicek,
AU  - W.
AU  - Sanford,
AU  - A.
AU  - Bano,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s40489-018-0141-9
L1  - internal-pdf://0568337678/Alresheed-2018-Academic and Related Skills Int.pdf
PY  - 2018
SP  - 311-326
T2  - Review Journal of Autism and Developmental Disorders
TI  - Academic and Related Skills Interventions for Autism: a 20-Year Systematic Review of Single-Case Research
UR  - &lt;Go to ISI&gt;://WOS:000452079900001
UR  - https://link.springer.com/article/10.1007%2Fs40489-018-0141-9
VL  - 5
ER  -
TY  - JOUR
AB  - One major predictor of depression onset is having a depressed parent. This study provides the first systematic review and meta-analysis of preventive interventions for offspring of depressed parents. 

We searched six literature databases and included randomized controlled trials which concerned the non-depressed offspring (aged 18 or younger) of a depressed parent, who received a preventive intervention designed to reduce the risk of depression or a comparison condition. 

Primary and secondary outcome measures were the severity and incidence of childhood depression. 14 publications reporting data from seven trials (n =935 children) were included and were of relatively high quality. 

The effect of the interventions (versus any control condition) on depressive and internalising symptoms at post-intervention follow-up (up to four months) was small but significant [g&#039;=-0.20, 95% CI (-0.34; -0.06), p =0.005; I &lt;sup&gt; 2 &lt;/sup&gt; =0.00%]. The interventions also had a small but significant effect on depression incidence [Risk Ratio=0.56; 95% CI(0.41;0.77); d&#039;=-0.42]. 

Intervention effects were not present in the short-term (up to 12months post-intervention) or long-term (15-72months post-intervention) follow-ups. Interventions targeting the offspring of depressed parents show promise not only in reducing symptoms of depression but also in preventing the onset of depression, at least immediately after the intervention. 

Copyright &copy; 2017 The Authors.
AN  - 620031569
AU  - Loechner,
AU  - J.
AU  - Starman,
AU  - K.
AU  - Galuschka,
AU  - K.
AU  - Tamm,
AU  - J.
AU  - Schulte-Korne,
AU  - G.
AU  - Rubel,
AU  - J.
AU  - Platt,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2017.11.009
L1  - internal-pdf://0228631600/Loechner-2018-Preventing depression in the off.pdf
PY  - 2018
T2  - Clinical Psychology Review.
TI  - Preventing depression in the offspring of parents with depression: A systematic review and meta-analysis of randomized controlled trials
UR  - http://www.elsevier.com/locate/clinpsychrev
UR  - https://www.sciencedirect.com/science/article/pii/S027273581730260X?via%3Dihub
ER  -
TY  - JOUR
AB  - **Introduction: **
Many clinicians are reluctant to use traditional mood-stabilizing agents, especially lithium, in children and adolescents. This review examined the evidence for lithium&#039;s safety and efficacy in this population. 

**Methods: **
A systematic review was conducted on the use of lithium in children and adolescents with bipolar disorder (BD). Relevant papers published through June 30&lt;sup&gt;th&lt;/sup&gt; 2018 were identified searching the electronic databases MEDLINE, Embase, PsycINFO and the Cochrane Library.

**Results:**
30 articles met inclusion criteria, including 12 randomized controlled trials (RCTs). Findings from RCTs demonstrate efficacy for acute mania in up to 50% of patients, and evidence of long-term maintenance efficacy. Lithium was generally safe, at least in the short term, with most common side effects being gastrointestinal, polyuria, or headache. Only a minority of patients experienced hypothyroidism. No cases of acute kidney injury or chronic kidney disease were reported. 

**Conclusions: **
Though the available literature is mostly short-term, there is evidence that lithium monotherapy is reasonably safe and effective in children and adolescents, specifically for acute mania and for prevention of mood episodes. 

Copyright &copy; 2018 Elsevier Masson SAS
AD  - (Amerio) Department of Mental Health, Mental Health Service of Fidenza, Parma, Italy (Amerio, Ghaemi) Mood Disorders Program, Tufts Medical Center, Boston, MA, United States (Ossola, Tonna, Marchesi) Department of Medicine and Surgery, Unit of Neuroscience, University of Parma, Parma, Italy (Scagnelli) Department of Mental Health, Mental Health Service of Fiorenzuola, Piacenza, Italy (Odone) School of Medicine, Vita-Salute San Raffaele University, Milan, Italy (Allinovi) Nephrology and Dialysis Unit Meyer Children&#039;s Hospital, Florence, Italy (Cavalli) Neuroscience Centre of Excellence, Meyer Children&#039;s Hospital, Florence, Italy (Iacopelli) Department of Health Sciences, A. Meyer Children&#039;s University Hospital, Florence, Italy (Ghaemi) Department of Psychiatry, Tufts University Medical School, Boston, MA, United States (Ghaemi) Novartis Institutes for Biomedical Research, Translational Medicine-Neuroscience, Cambridge, MA, United StatesA. Amerio, Department of Mental Health, Mental Health Service of Fidenza, Via Berenini 153, Fidenza, Parma, Italy. E-mail: andrea.amerio@studenti.unipr.it
AN  - 2001035567
AU  - Amerio,
AU  - A.
AU  - Ossola,
AU  - P.
AU  - Scagnelli,
AU  - F.
AU  - Odone,
AU  - A.
AU  - Allinovi,
AU  - M.
AU  - Cavalli,
AU  - A.
AU  - Iacopelli,
AU  - J.
AU  - Tonna,
AU  - M.
AU  - Marchesi,
AU  - C.
AU  - Ghaemi,
AU  - S.
AU  - N.
DA  - October
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.eurpsy.2018.07.012
DP  - Ovid Technologies
KW  - Adolescents
KW  - Bipolar
KW  - Children
KW  - Depression
KW  - Efficacy
KW  - Lithium
KW  - Safety
KW  - abdominal cramp/si [Side Effect]
KW  - acute kidney failure/si [Side Effect]
KW  - adolescent
KW  - adolescent disease/dt [Drug Therapy]
KW  - adolescent disease/ep [Epidemiology]
KW  - adolescent disease/pc [Prevention]
KW  - bibliographic database
KW  - bipolar disorder/dt [Drug Therapy]
KW  - bipolar disorder/ep [Epidemiology]
KW  - bipolar disorder/pc [Prevention]
KW  - bipolar I disorder
KW  - body weight gain
KW  - child
KW  - childhood disease/dt [Drug Therapy]
KW  - childhood disease/ep [Epidemiology]
KW  - childhood disease/pc [Prevention]
KW  - chronic kidney failure/si [Side Effect]
KW  - comparative effectiveness
KW  - comparative study
KW  - diarrhea/si [Side Effect]
KW  - drug efficacy
KW  - drug safety
KW  - drug tolerability
KW  - emergency care
KW  - enuresis/si [Side Effect]
KW  - gastrointestinal symptom/si [Side Effect]
KW  - goiter/si [Side Effect]
KW  - human
KW  - hypothyroidism/si [Side Effect]
KW  - long term care
KW  - medical record
KW  - mental patient
KW  - meta analysis
KW  - mixed mania and depression
KW  - monotherapy
KW  - nausea/si [Side Effect]
KW  - outcome assessment
KW  - polydipsia/si [Side Effect]
KW  - polyuria/si [Side Effect]
KW  - practice guideline
KW  - priority journal
KW  - prophylaxis
KW  - short survey
KW  - stomach pain/si [Side Effect]
KW  - systematic review
KW  - tremor/si [Side Effect]
KW  - vomiting/si [Side Effect]
KW  - lithium/ae [Adverse Drug Reaction]
KW  - lithium/dt [Drug Therapy]
L1  - internal-pdf://0156104847/Amerio-2018-Safety and efficacy of lithium in.pdf
LA  - English
M3  - Short Survey
PY  - 2018
SP  - 85-97
T2  - European Psychiatry
TI  - Safety and efficacy of lithium in children and adolescents: A systematic review in bipolar illness
UR  - http://www.elsevier.com/locate/europsych
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2001035567
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.eurpsy.2018.07.012&amp;issn=0924-9338&amp;isbn=&amp;volume=54&amp;issue=&amp;spage=85&amp;pages=85-97&amp;date=2018&amp;title=European+Psychiatry&amp;atitle=Safety+and+efficacy+of+lithium+in+children+and+adolescents%3A+A+systematic+review+in+bipolar+illness&amp;aulast=Amerio&amp;pid=%3Cauthor%3EAmerio+A.%3C%2Fauthor%3E%3CAN%3E2001035567%3C%2FAN%3E%3CDT%3EShort+Survey%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S0924933818301470/1-s2.0-S0924933818301470-main.pdf?_tid=27f7443a-8f55-4cfe-bbff-cb8a7cbd5adc&amp;acdnat=1539256756_d95c246e0d1bd74b37b4ec72d030764b
VL  - 54
ER  -
TY  - JOUR
AB  - **Background. **
Current literature shows that posttraumatic stress disorder and complex posttraumatic stress disorder symptoms differ. Although the psychological treatments available for posttraumatic disorder are well established, little is known about the effectiveness of those aimed at the treatment of complex posttraumatic stress. 

**Objective. **
To evaluate the efficacy of psychological treatments for complex posttraumatic stress disorder. 

**Method. **
A systematic qualitative search was conducted according to PRISMA guidelines, searching four psychological and health electronic databases: Medline, Pilots, PsycINFO, and Pubmed. Three reviewers independently selected the studies in two phases: preselection (criteria for complex posttraumatic stress disorder, replicable psychological treatment, and treatment effect) and selection (additional criteria: type of study, participants, and treatment). 

**Results.**
Of the 615 studies reviewed, 25 were preselected, eight of which met the inclusion and methodological quality criteria. Five studies explored adult populations (with one exception, all were randomized clinical trials) and three child populations (clinical studies with pre-post-treatment design, with and without control group). Most studies with adult populations included psychoeducation, cognitive re-structuration, and exposure therapy. The studies with child samples included EMDR and mindfulness as the most frequent treatment components. 

**Discussion and conclusion. **
The evidence was insufficient to determine the most effective treatment. More research on this issue is required.
AD  - [Fernandez Fillol, Carmen; Rocio Serrano-Ibanez, Elena; Teresa Ruiz-Parraga, Gema; Ramirez Maestre, Carmen; Esteve Zarazaga, Rosa; Lopez Martinez, Alicia Eva] Univ Malaga, Dept Personalidad Evaluac &amp; Tratamiento Psicol, Fac Psicol, Ctr Invest Biomed IBIMA, Malaga, Spain.Serrano-Ibanez, ER (reprint author), Univ Malaga, Dept Personalidad Evaluac &amp; Tratamiento Psicol, Fac Psicol, Campus Teatinos Bulevar Louis Pasteur,25, Malaga 29010, Spain.elenarserrano@uma.es
AN  - WOS:000436465100005
AU  - Fillol,
AU  - C.
AU  - F.
AU  - Serrano-Ibanez,
AU  - E.
AU  - R.
AU  - Ruiz-Parraga,
AU  - G.
AU  - T.
AU  - Maestre,
AU  - C.
AU  - R.
AU  - Zarazaga,
AU  - R.
AU  - E.
AU  - Martinez,
AU  - A.
AU  - E.
AU  - L.
DA  - Mar-Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.17711/sm.0185-3325.2018.013
J2  - Salud Ment.
KW  - Complex posttraumatic stress disorder
KW  - psychological treatment
KW  - effectiveness
KW  - therapy efficacy
KW  - adverse childhood experiences
KW  - trauma
KW  - ptsd
KW  - abuse
KW  - adults
KW  - neurobiology
KW  - survivors
KW  - symptoms
KW  - health
KW  - women
KW  - Psychiatry
L1  - internal-pdf://0503183629/Fillol-2018-Effective therapies for the treatm.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GK8IOTimes Cited: 0Cited Reference Count: 37Fernandez Fillol, Carmen Rocio Serrano-Ibanez, Elena Teresa Ruiz-Parraga, Gema Ramirez Maestre, Carmen Esteve Zarazaga, Rosa Lopez Martinez, Alicia Eva0Inst nac psiquiatria ramon fuente munizMexico city
PY  - 2018
SP  - 81-90
T2  - Salud Mental
TI  - Effective therapies for the treatment of complex posttraumatic stress disorder: A qualitative systematic review
UR  - &lt;Go to ISI&gt;://WOS:000436465100005
UR  - http://revistasaludmental.mx/index.php/salud_mental/article/download/SM.0185-3325.2018.013/3401
VL  - 41
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Although antenatal iron supplementation is beneficial to mothers, its impact on the neurodevelopment of offspring is controversial. A systematic review and meta-analysis was undertaken to assess whether routine maternal antenatal iron supplementation confers later neurodevelopmental benefit to offspring.

**METHODS: **
Electronic databases were searched using MESH terms or key words and identified papers were reviewed by two independent reviewers. The study quality was assessed using the Cochrane risk of bias assessment tool. The review was registered in the PROSPERO CRD data base. 

**RESULTS: **
Seven publications were identified, based on four randomised trials published between 2006 and 2016. Three of the trials were in the Asian sub-continent. A range of tools were used to evaluate neurodevelopment. Meta-analysis of outcomes from the three RCTs meeting our inclusion criteria showed minimal effect of antenatal iron supplementation on the neurodevelopment of offspring, which was not statistically significant: weighted mean difference of 0.54 (95% CI: -0.67 to 1.75); test for overall effect Z = 0.87; p = 0.38; and heterogeneity 48%. Meta-analysis of outcomes of these RCTs at later stages of development produced similar results. 

**CONCLUSIONS: **
The benefit of routine antenatal iron supplementation on neurodevelopment in offspring was not statistically significant in this relatively limited set of trials, and some benefit cannot be excluded in areas with a high prevalence of maternal anaemia. A large randomized controlled trial showing significant benefit would be required to modify our conclusions.
AN  - 29728086
AU  - Jayasinghe,
AU  - C.
AU  - Polson,
AU  - R.
AU  - van
AU  - Woerden,
AU  - H.
AU  - C.
AU  - Wilson,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s12887-018-1118-7
L1  - internal-pdf://0730991774/Jayasinghe-2018-The effect of universal matern.pdf
PY  - 2018
SP  - 150
T2  - BMC Pediatrics
TI  - The effect of universal maternal antenatal iron supplementation on neurodevelopment in offspring: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=29728086
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936025/pdf/12887_2018_Article_1118.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - **Importance **
Children with neurodevelopmental disorders have a higher prevalence of sleep disturbances. Currently there is variation in the use of melatonin; hence, an up-to-date systematic review is indicated to summarise the current available evidence. 

**Objective **
To determine the efficacy and safety of melatonin as therapy for sleep problems in children with neurodevelopmental disorders. 

**Data sources and study selections **
PubMed, Embase, the Cumulative Index to Nursing and Allied Health Literature and the Cochrane Central Register of Controlled Trials were searched from inception up to January 2018. Two reviewers performed data assessment and extraction. We assessed randomised controlled trials that compared melatonin with placebo or other intervention for the management of sleep disorders in children (&lt;18 years) with neurodevelopmental disorders. 

**Data extraction and synthesis **
We identified 3262 citations and included 13 studies in this meta-analysis. Main outcomes Main outcomes included total sleep time, sleep onset latency, frequency of nocturnal awakenings and adverse events. 

**Results **
Thirteen randomised controlled trials (n=682) met the inclusion criteria. A meta-analysis of nine studies (n=541) showed that melatonin significantly improved total sleep time compared with placebo (mean difference (MD)=48.26 min, 95% CI 36.78 to 59.73, I 2 =31%). In 11 studies (n=581), sleep onset latency improved significantly with melatonin use (MD=-28.97, 95% CI -39.78 to -18.17). No difference was noted in the frequency of nocturnal awakenings (MD=-0.49, 95% CI -1.71 to 0.73). No medication-related serious adverse event was reported. 

**Conclusion **
Melatonin appeared safe and effective in improving sleep in the studied children. The overall quality of the evidence is limited due to heterogeneity and inconsistency. Further research is needed. 

Copyright &copy; Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. 
All rights reserved. No commercial use is permitted unless otherwise expressly granted.
AN  - 622810894
AU  - Abdelgadir,
AU  - I.
AU  - S.
AU  - Gordon,
AU  - M.
AU  - A.
AU  - Akobeng,
AU  - A.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/archdischild-2017-314181
L1  - internal-pdf://3417381419/Abdelgadir-2018-Melatonin for the management o.pdf
PY  - 2018
SP  - 1155-1162
T2  - Archives of Disease in Childhood
TI  - Melatonin for the management of sleep problems in children with neurodevelopmental disorders: A systematic review and meta-analysis
UR  - http://adc.bmjjournals.com
UR  - https://adc.bmj.com/content/archdischild/103/12/1155.full.pdf
VL  - 103
ER  -
TY  - JOUR
AB  - **Purpose**
In this review we examined previous studies of psychological interventions for runaway and homeless youth and evaluated the effectiveness of these interventions in terms of mental health outcomes. DesignLiterature review. 

**Methods**
A search of various databases, including PubMed, EMBASE, Cochrane Library, PsycINFO, and the Cumulative Index to Nursing and Allied Health Literature (CINAHL), was conducted. In this review we systematically described the characteristics of the included studies and interventions, and conducted a narrative synthesis and meta-analyses of the mental health outcomes of the interventions. 

**Findings**
Five types of psychological interventions were identified in the included 11 studies: art therapy, cognitive behavioral therapy (CBT)-based interventions, family therapy, motivational interviewing, and strengths-based interventions. The narrative synthesis found positive effects of family therapy on substance use and positive effects of CBT-based interventions on depression. However, according to the meta-analyses, none of the interventions had any significant effects. 

**Conclusions**
Family therapies are likely to be effective in cases of substance use, and CBT-based interventions are likely to be effective in dealing with cases of depression. However, as the quantitative synthesis did not support the effects of any of the psychological interventions on mental health outcomes, further research is needed. Clinical 

**Relevance**
Nurse-led interventions were identified in two studies. Mental health nurses should assess the mental health status of runaway and homeless youth and provide timely and effective interventions.
AD  - [Noh, Dabok] Eulji Univ, Coll Nursing, Seongnam, South Korea.Noh, D (reprint author), Eulji Univ, Coll Nursing, Seongnam Si 13135, Gyeonggi Do, South Korea.daboknoh@gmail.com
AN  - WOS:000443398700002
AU  - Noh,
AU  - D.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jnu.12402
J2  - J. Nurs. Scholarsh.
KW  - Mental health
KW  - psychological intervention
KW  - runaway and homeless youth
KW  - brief motivational intervention
KW  - street-involved youth
KW  - substance use
KW  - south-korea
KW  - sexual risk
KW  - adolescents
KW  - therapy
KW  - disorder
KW  - behavior
KW  - alcohol
KW  - Nursing
L1  - internal-pdf://2963808627/Noh-2018-Psychological Interventions for Runaw.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: GS2QTTimes Cited: 0Cited Reference Count: 24Noh, DabokNoh, Dabok/0000-0002-2533-55150WileyHoboken1547-5069
PY  - 2018
SP  - 465-472
T2  - Journal of Nursing Scholarship
TI  - Psychological Interventions for Runaway and Homeless Youth
UR  - &lt;Go to ISI&gt;://WOS:000443398700002
UR  - https://sigmapubs.onlinelibrary.wiley.com/doi/pdf/10.1111/jnu.12402
VL  - 50
ER  -
TY  - JOUR
AB  - **OBJECTIVE**
Gilles de la Tourette syndrome (GTS) is a disorder characterized by motor and vocal tics. Although by definition the onset of GTS is before age 18 years, clinical trials of deep brain stimulation (DBS) have been conducted only in adults. Using individual participant data (IPD) meta-analysis methodology, the current study investigated the safety and efficacy of DBS as a treatment for GTS in children and youth.

**METHODS**
A systematic review with no date or language restrictions was performed according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. Three electronic databases were searched: PubMed, EMBASE, and Web of Science. From 843 articles screened, the IPD of 58 children and youth (ages 12-21 years) extracted from 21 articles were collected and analyzed. A mixed-effects univariable analysis followed by multivariable hierarchical regression was performed using change in the Yale Global Tic Severity Scale (YGTSS) score as the primary outcome and reported measures of comorbidities as secondary outcomes.

**RESULTS**
The authors&#039; results showed an average improvement of 57.5% +/- 24.6% across studies on the YGTSS. They also found that comorbid depression and stimulation pulse width each correlated negatively with outcome (p &lt; 0.05). In patients with less severe GTS, greater improvements were evident following thalamic stimulation. More than one-quarter (n = 16, 27.6%) of participants experienced side effects, the majority of which were minor.

**CONCLUSIONS**
DBS in the pediatric population may be an effective option with a moderate safety profile for treatment of GTS in carefully selected children and youth. Large, prospective studies with long-term follow-up are necessary to understand how DBS influences tic symptoms and may alter the natural course of GTS in children.
AN  - 30497215
AU  - Coulombe,
AU  - M-A.
AU  - Gorman,
AU  - D.
AU  - A.
AU  - Weil,
AU  - A.
AU  - G.
AU  - Elkaim,
AU  - L.
AU  - M.
AU  - Alotaibi,
AU  - N.
AU  - M.
AU  - Fallah,
AU  - A.
AU  - Kalia,
AU  - S.
AU  - K.
AU  - Lipsman,
AU  - N.
AU  - Lozano,
AU  - A.
AU  - M.
AU  - Ibrahim,
AU  - G.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3171/2018.7.PEDS18300
L1  - internal-pdf://3832223018/Anonymous-2018-Deep brain stimulation for Gill.pdf
PY  - 2018
SP  - 1-11
T2  - Journal of Neurosurgery
TI  - Deep brain stimulation for Gilles de la Tourette syndrome in children and youth: a meta-analysis with individual participant data
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30497215
UR  - https://thejns.org/pediatrics/view/journals/j-neurosurg-pediatr/aop/article-10.3171-2018.7.PEDS18300.xml
VL  - Pediatrics..
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering av effektene av Parent Management Training- Oregonmodellen (PMTO), gitt som et individuelt foreldreveiledningstiltak.  Tiltaket består av ukentlige veiledningsmøter med foreldre, av ulik varighet. Målgruppen er familier med barn som har atferdsvansker. Tiltaket er utviklet ved Oregon Social Learning Center. Nasjonalt utviklingssenter for barn og unge (NUBU; tidligere Atferdssenteret AS) har de norske rettighetene.

METODE
Litteratursøk i Embase, Medline, Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS, SweMed ble supplert med to artikler. Totalt 26 artikler ble funnet å være relevante, hvorav ni publikasjoner basert på syv studier undersøker tiltakets effekt/effektivitet.

RESULTATER
PMTO er et godt beskrevet tiltak med en systematisk implementeringsstrategi. Det er gjennomført &eacute;n norsk og &eacute;n islandsk RCT effektivitetsstudie med målinger før og etter behandling og &eacute;n norsk studie av langtidseffekter ett år etter avsluttet behandling.  I tillegg er det gjennomført &eacute;n studie på effektene ved spredningen av tiltaket i vanlig praksis i Norge, som også er brukt for å evaluere
effektene av PMTO på undergrupper. Effektene av PMTO er også sammenlignet med et annet foreldreveiledningsprogram (De utrolige Årene; DuÅ). Det er gjennomført &eacute;n norsk og &eacute;n islandsk studie av metodeintegritet. Alle studiene holder moderat høy forskningsmetodisk kvalitet. Med unntak av sammenligningen med DuÅ er det funnet statistisk signifikante effekter av PMTO som, selv om de er små og ikke helt konsistente, er funnet å ha praktisk betydning. Testing av statistiske modeller tyder på at tiltakets virkningsmekanisme er i tråd med tiltakets teoretiske modell.

KONKLUSJON
PMTO som individuelt foreldreveiledningstiltak for barn med atferdsvansker klassifiseres på evidensnivå 5 &ndash; Tiltak med sterk dokumentasjon på effekt.
AU  - Stormark,
AU  - K.
AU  - M.,
AU  - Christiansen,
AU  - Ø.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2018
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Parent Management Training &ndash; The Oregon Model (PMTO) som individuell foreldreveiledning (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/parent-management-training-the-oregon-model-pmto-som-individuell-foreldreveiledning-2-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - **BACKGROUND**
Substance use disorders (SUDs) among youth are a major public health problem. In the United States, for example, the incidence of SUDs increases steadily after age 12 and peaks among youth ages 18&ndash;23 (White, Evans, Ali, Achara‐Abrahams, &amp; King, 2009). Although not every youth who experiments with alcohol or illicit drugs is diagnosed with an SUD, approximately 7&ndash;9% of 12&ndash;24 year olds in the United States were admitted for public SUD treatment in 2013 (Substance Abuse and Mental Health Services Administration [SAMHSA], 2016). Recovery from an SUD involves reduction or complete abstinence of use, defined broadly as &ldquo;voluntarily sustained control over substance use, which maximises health and wellbeing and participation in the rights, roles and responsibilities of society&rdquo; (UK Drug Policy Commission, 2008). However, SUDs are often experienced as chronic conditions; among youth who successfully complete substance use treatment, approximately 45&ndash;70% return to substance use within months of treatment discharge (Anderson, Ramo, Schulte, Cummins, &amp; Brown, 2007; Brown, D&rsquo;Amico, McCarthy, &amp; Tapert, 2001; Ramo, Prince, Roesch, &amp; Brown, 2012; White et al., 2004). Thus, multiple treatment episodes and ongoing recovery supports after treatment are often necessary to assist with the recovery process (Brown et al., 2001; Ramo et al., 2012; White et al., 2004).

Success and engagement at school and in postsecondary education are critical to healthy youth development. For youth in recovery from SUDs, school attendance, engagement, and achievement build human capital by motivating personal growth, creating new opportunities and social networks, and increasing life satisfaction and meaning (Keane, 2011; Terrion, 2012; 2014). Upon discharge from formal substance use treatment settings, schools become one of the most important social environments in the lives of youth with SUDs. Healthy school peer environments can enable youth to replace substance use behaviors and norms with healthy activities and prosocial, sober peers. Conversely, many school environments may be risky for youth in recovery from SUDs due to perceived substance use among peers, availability of drugs or alcohol, and substance‐approving norms on campus (Centers for Disease Control [CDC], 2011; Spear &amp; Skala, 1995; Wambeam, Canen, Linkenbach, &amp; Otto, 2014).

Given the many social and environmental challenges faced by youth in recovery from substance use, recovery‐specific institutional supports are increasingly being linked to educational settings. The two primary types of education‐based continuing care supports for youth in recovery, defined under the umbrella term of &ldquo;recovery schools&rdquo; for this review, are recovery high schools (RHSs) and collegiate recovery communities (CRCs). RHSs are secondary schools that provide standard high school education and award secondary school diplomas, but also include therapeutic programming aimed at promoting recovery (e.g., group check‐ins, community service, counseling sessions). CRCs also provide recovery oriented support services (e.g., self‐help groups, counseling sessions, sober dorms) for students, but are embedded within larger college or university settings. The primary aims of RHSs and CRCs are to promote abstinence and prevent relapse among students, and thus ultimately improve students&#039; academic success.

**OBJECTIVES**
This review summarized and synthesized the available research evidence on the effects of recovery schools for improving academic success and behavioural outcomes among high school and college students who are in recovery from substance use. The specific research questions that guided the review are as follows:

1. What effect does recovery school attendance (versus attending a non‐recovery or traditional school setting) have on academic outcomes for students in recovery from substance use? Specifically (by program type):
a. For recovery high schools: what are the effects on measures of academic achievement, high school completion, and college enrolment?
b. For collegiate recovery communities: what are the effects on measures of academic achievement and college completion?
2. What effect does recovery school attendance have on substance use outcomes for students in recovery from substance use? Specifically, what are the effects on alcohol, marijuana, cocaine, or other substance use?
3. Do the effects of recovery schools on students&#039; outcomes vary according to the race/ethnicity, gender, or socioeconomic status of the students?
4. Do the effects of recovery schools on students&#039; outcomes vary according to existing mental health comorbidity status or juvenile justice involvement of the students?
SEARCH METHODS
We aimed to identify all published and unpublished literature on recovery schools by using a comprehensive and systematic literature search. We searched multiple electronic databases, research registers, grey literature sources, and reference lists from prior reviews; and contacted experts in the field.

**SELECTION CRITERIA**
Studies were included in the review if they met the following criteria:

**Types of studies: **Randomized controlled trial (RCT), quasi‐randomized controlled trial (QRCT), or controlled quasi‐experimental design (QED).

**Types of participants: **Students in recovery from substance use who were enrolled part‐time or full‐time in secondary (high school) or postsecondary (college or university) educational institutions.

**Types of interventions:** Recovery schools broadly defined as educational institutions, or programs at educational institutions, developed specifically for students in recovery and that address recovery needs in addition to academic development.

**Types of comparisons: **Traditional educational programs or services that did not explicitly have a substance use recovery focus.

**Types of outcome measures: **The review focused on primary outcomes in the following two domains: academic performance (e.g., achievement test scores, grade‐point average, high school completion, school attendance, college enrolment, college completion) and substance use (alcohol, marijuana, cocaine, heroin, stimulant, mixed drug use, or other illicit drug use). Studies that met all other eligibility criteria were considered eligible for the narrative review portion of this review even if they did not report outcomes in one of the primary outcome domains.

**Other criteria: **Studies must have been reported between 1978 and 2016. The search was not restricted by geography, language, publication status, or any other study characteristic.

**DATA COLLECTION AND ANALYSIS**
Two reviewers independently screened all titles and abstracts of records identified in the systematic search. Records that were clearly ineligible or irrelevant were excluded at the title/abstract phase; all other records were retrieved in full‐text and screened for eligibility by two independent reviewers. Any discrepancies in eligibility assessments were discussed and resolved via consensus. Studies that met the inclusion criteria were coded by two independent reviewers using a structured data extraction form; any disagreements in coding were resolved via discussion and consensus. If members of the review team had conducted any of the primary studies eligible for the review, external and independent data collectors extracted data from those studies. Risk of bias was assessed using the ROBINS‐I tool for non‐randomized study designs (Sterne, Higgins, &amp; Reeves, 2016).

Inverse variance weighted random effects meta‐analyses were planned to synthesize effect sizes across studies, as well as heterogeneity analysis, subgroup analysis, sensitivity analysis, and publication bias analysis. However, these synthesis methods were not used given that only one study met the inclusion criteria for the review. Instead, effect sizes (and their corresponding 95% confidence intervals) were reported for all eligible outcomes reported in the study.

**RESULTS**
Only one study met criteria for inclusion in the review. This study used a QED to examine the effects of RHSs on high school students&#039; academic and substance use outcomes. No eligible studies examining CRCs were identified in the search.

The results from the one eligible RHS study indicated that after adjusting for pretest values, students in the RHS condition reported levels of grade point averages (= 0.26, 95% CI [‐0.04, 0.56]), truancy (= 0.01, 95% CI [‐0.29, 0.31]), and alcohol use (= 0.23, 95% CI [‐0.07, 0.53]) similar to participants in the comparison condition. However, students in the RHS condition reported improvements in absenteeism (= 0.56, 95% CI [0.25, 0.87]), abstinence from alcohol/drugs (OR = 4.36, 95% CI [1.19, 15.98]), marijuana use (= 0.51, 95% CI [0.20, 0.82]), and other drug use (= 0.45, 95% CI [0.14, 0.76]).

Overall, there was a serious risk of bias in the one included study. The study had a serious risk of bias due to confounding, low risk of bias due to selection of participants into the study, moderate risk of bias due to classification of interventions, inconclusive risk of bias due to deviations from intended interventions, inconclusive risk of bias due to missing data, moderate risk of bias in measurement of outcomes, and low risk of bias in selection of reported results.

**AUTHORS&rsquo; CONCLUSIONS**
There is insufficient evidence regarding the effectiveness of RHSs and CRCs for improving academic and substance use outcomes among students in recovery from SUDs. Only one identified study examined the effectiveness of RHSs. Although the study reported some beneficial effects, the results must be interpreted with caution given the study&#039;s potential risk of bias due to confounding and limited external validity. No identified studies examined the effectiveness of CRCs across the outcomes of interest in this review, so it is unclear what effects these programs may have on students&#039; academic and behavioral outcomes.

The paucity of evidence on the effectiveness of recovery schools, as documented in this review, thus suggest the need for caution in the widespread adoption of recovery schools for students in recovery from SUDs. Given the lack of empirical support for these recovery schools, additional rigorous evaluation studies are needed to replicate the findings from the one study included in the review. Furthermore, additional research examining the costs of recovery schools may be needed, to help school administrators determine the potential cost‐benefits associated with recovery schools.
AU  - Hennessy,
AU  - E.
AU  - A.
AU  - Tanner-Smith,
AU  - E.
AU  - E.
AU  - Finch,
AU  - A.
AU  - J.
AU  - Sathe,
AU  - N.
AU  - Kugley,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.4073/csr.2018.9
L1  - internal-pdf://2270284253/Hennessy-2018-Recovery schools for improving b.pdf
PY  - 2018
T2  - Campbell Systematic Reviews
TI  - Recovery schools for improving behavioral and academic outcomes among students in recovery from substance use disorders
ER  -
TY  - JOUR
AB  - **Innledning** 
Folkehelseinstituttet ble i september 2016 bedt av Vestre Viken helseforetak om å utarbeide en systematisk oversikt om effekt og bivirkninger ved langtidsbehandling med antipsykotika. Antipsykotika er standardbehandling ved schizofreni, og randomiserte kontrollerte studier med oppfølgingstid opp til to år viser at behandlingen demper positive psykotiske symptomer, reduserer risikoen for tilbakefall, øker livskvalitet og gir færre re‐innleggelser i opptil to år. Den nåværende nasjonale retningslinjen åpner opp for vedlikeholdsbehandling utover to år, men langt mindre forskning har undersøkt effekten av behandling med antipsykotika over lengre tid enn to år. Formål Utarbeide en systematisk oversikt for å besvare følgende spørsmål: Hva er effekter og bivirkninger av å bruke antipsykotika i to år eller lengre hos pasienter med schizofreni‐ spektrumlidelser? 

**Metode** 
Vi har søkt i ni elektroniske databaser etter systematiske oversikter om effekter av bruk av antipsykotika i to år eller lenger hos personer med diagnosene F20 og F22‐F29 i ICD‐10 og kodene 295.40 Schizophreniform, 295.70 Schizoaffektive, 295.90 Schizoph‐ renia, 297.1 Delusional disorder, og 298.9 Unspecified SZ i DSM‐5, kalt schizofreni spektrumdiagnoser. Vi har også søkt etter primærstudier for å fange opp studier som ikke var inkludert i systematiske oversikter. Til slutt har vi gjennomgått litteratur som vi har fått av fagfellene. De inkluderte studiene er kvalitetsvurdert med sjekkliste og vi vurderer vår tillit til resultatene ved hjelp av GRADE. 

**Resultat** 
Søket etter systematiske oversikter gav 3987 treff, men vi inkluderte ingen. Et nytt søk etter primærstudier gav 12640 treff, og vi inkluderte åtte studier på tre pasientutvalg. Studiene var beskrevet i &eacute;n doktoravhandling og syv artikler. Studiene var fra Finland, Sverige og USA. I studiene fra finske og svenske registre var mortaliteten hos pasienter som hadde brukt antipsykotika i mer enn to år lavere enn hos pasienter som ikke hadde brukt anti‐ psykotika, men de absolutte forskjellene var små og vi kan ikke fastslå om det er en år‐ sakssammenheng. I en studie fra USA ble pasienter uten antipsykotika funnet å ha bedre arbeidsmessig fungering enn pasienter som hadde brukt antipsykotika i mer enn to år. Pasienter uten antipsykotika hadde i denne studien sjeldnere positive og negative symptomer. Risiko for rehospitalisering varierte ut fra legemiddel, og tallene var usikre. Heller ikke her kan vi fastslå om det er en årsakssammenheng. Resultater på viktige utfall som parkinsonisme og metabolske forstyrrelser mangler i de inkluderte studiene. 

**Diskusjon** 
Det er ikke gjort randomiserte kontrollerte studier hvor den reelle behandlingstiden overstiger to år. Registerstudier fra Finland og Sverige gir imidlertid mulighet for å koble informasjon om diagnoser med uthenting av resepter og kan potensielt gi verdi‐ full støtte til kliniske retningslinjer. Men studiene som er gjort gir svak støtte til en år‐ sakssammenheng mellom langtidsbruk av antipsykotika og mortalitet. Den lille studien fra USA kan heller ikke fastslå årsaksforhold mellom arbeidsfungering og langtidsbruk av antipsykotika. 

**Konklusjon** 
Spørsmålet om virkninger og bivirkninger av langtidsbehandling (lenger enn to år) med antipsykotika er vanskelig å besvare, selv med de beste forskningsmetoder. Derfor har vi svært lav tillit til dokumentasjonen. Studier av legemiddelbruk og mortalitet fra nasjonale registre i Finland og Sverige fant at pasienter som hadde brukt antipsykotika over lang tid hadde lavere mortalitet enn pasienter som ikke hadde brukt antipsykotika, men det er vanskelig å fastslå en årsakssammenheng. En studie fra Chicago fant at pasienter som ikke hadde brukt antipsykotika over en periode på 20 år hadde større sannsynlighet for å være i jobb og hadde bedre arbeidsmessig fungering enn pasienter som hadde brukt antipsykotika sammenhengende i denne perioden. Studien er imidlertid liten og hadde stort frafall. Også her er det vanskelig å fastslå en årsakssammenheng.
AU  - Smedslund,
AU  - G.
AU  - Siqveland,
AU  - J.
AU  - Kirkehei,
AU  - I.
AU  - Steiro,
AU  - A.
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/langtidsbehandling-antipsykotika-schizofrenispektrum-rapport-2018-v2.pdf
PY  - 2018
T2  - Folkehelseinstituttet
TI  - Langtidsbehandling med antipsykotika hos personer med schizofrenispektrumlidelser: en systematisk oversikt
ER  -
TY  - JOUR
AB  - This study is to compare the efficacy of enuresis alarm and desmopressin therapy in managing pediatric monosymptomatic enuresis. We performed systematic literature searches on different databases from inception until April 2017 without language restriction. All randomized control trials comparing an enuresis alarm and desmopressin in managing children with monosymptomatic enuresis were included. A total of 15 studies with 1502 participants (aged 5 to 16 years) were included for pooled analysis. Overall, an enuresis alarm outperformed desmopressin in achieving at least a partial response (&gt;50% reduction in wet nights) in per-protocol analysis (OR: 1.53, 95% CI 1.05 to 2.23) but not in intention-to-treat analysis (OR: 0.97, 95% CI 0.73 to 1.30) as the alarm was hampered by a high dropout rate (OR: 2.20, 95% CI 3.41 to 4.29). However, alarm therapy yielded a better sustained response (OR: 2.89, 95% CI 1.38 to 6.04) and lower relapse rate (OR: 0.25, 95% CI 0.12 to 0.50). In the intention to treat analysis, the results revealed that alarm and desmopressin therapy are comparable in efficacy with regards to achieving &gt;50% reduction in baseline wet nights in enuretic children. However, enuresis alarms offer a superior treatment response and a lower relapse rate in well-motivated children.
AD  - Peng, Carol Chiung-Hui. Department of Internal Medicine, University of Maryland Medical Center Midtown Campus, Baltimore, Maryland, 21201, USA.Peng, Carol Chiung-Hui. Division of Urology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, 231, Taiwan.Peng, Carol Chiung-Hui. School of Medicine, Buddhist Tzu Chi University, Hualien, 970, Taiwan.Yang, Stephen Shei-Dei. Division of Urology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, 231, Taiwan.Yang, Stephen Shei-Dei. School of Medicine, Buddhist Tzu Chi University, Hualien, 970, Taiwan.Austin, Paul F. Department of Urology, Texas Children&#039;s Hospital and Baylor College of Medicine, Houston, Texas, 77030, USA.Chang, Shang-Jen. Division of Urology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, 231, Taiwan. krissygnet@gmail.com.Chang, Shang-Jen. School of Medicine, Buddhist Tzu Chi University, Hualien, 970, Taiwan. krissygnet@gmail.com.
AN  - 30425276
AU  - Peng,
AU  - C.
AU  - C.
AU  - Yang,
AU  - S.
AU  - S.
AU  - Austin,
AU  - P.
AU  - F.
AU  - Chang,
AU  - S.
AU  - J.
DA  - 11 13
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1038/s41598-018-34935-1
DP  - Ovid Technologies
J2  - Sci
KW  - Child
KW  - *Clinical Alarms
KW  - *Deamino Arginine Vasopressin/tu [Therapeutic Use]
KW  - Humans
KW  - *Nocturnal Enuresis/dt [Drug Therapy]
KW  - Nocturnal Enuresis/pp [Physiopathology]
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
KW  - ENR1LLB0FP (Deamino Arginine Vasopressin)
L1  - internal-pdf://1508660193/Peng-2018-Systematic Review and Meta-analysis.pdf
LA  - English
M3  - Meta-Analysis
Research Support, Non-U.S. Gov&#039;t
Systematic Review
N1  - Peng, Carol Chiung-HuiYang, Stephen Shei-DeiAustin, Paul FChang, Shang-Jen
PY  - 2018
SP  - 16755
T2  - Scientific Reports
TI  - Systematic Review and Meta-analysis of Alarm versus Desmopressin Therapy for Pediatric Monosymptomatic Enuresis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=30425276
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30425276&amp;id=doi:10.1038%2Fs41598-018-34935-1&amp;issn=2045-2322&amp;isbn=&amp;volume=8&amp;issue=1&amp;spage=16755&amp;pages=16755&amp;date=2018&amp;title=Scientific+Reports&amp;atitle=Systematic+Review+and+Meta-analysis+of+Alarm+versus+Desmopressin+Therapy+for+Pediatric+Monosymptomatic+Enuresis.&amp;aulast=Peng&amp;pid=%3Cauthor%3EPeng+CC%3C%2Fauthor%3E%3CAN%3E30425276%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233184/pdf/41598_2018_Article_34935.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **Objectives **
To systematically review evidence on the effectiveness of interventions including integration of academic and health education for reducing physical aggression and violence, and describe the content of these interventions. 

**Data sources **
Between November and December 2015, we searched 19 databases and 32 websites and consulted key experts in the field. We updated our search in February 2018. 

**Eligibility criteria **
We included randomised trials of school-based interventions integrating academic and health education in students aged 4-18 and not targeted at health-related subpopulations (eg, learning or developmental difficulties). We included evaluations reporting a measure of interpersonal violence or aggression. 

**Data extraction and analysis **
Data were extracted independently in duplicate, interventions were analysed to understand similarities and differences and outcomes were narratively synthesised by key stage (KS). 

**Results **
We included 13 evaluations of 10 interventions reported in 20 papers. Interventions included either full or partial integration, incorporated a variety of domains beyond the classroom, and used literature, local development or linking of study skills and health promoting skills. Evidence was concentrated in KS2, with few evaluations in KS3 or KS4, and evaluations had few consistent effects; evaluations in KS3 and KS4 did not suggest effectiveness. 

**Discussion **
Integration of academic and health education may be a promising approach, but more evidence is needed. Future research should consider the lifecourse&#039; aspects of these interventions; that is, do they have a longitudinal effect? Evaluations did not shed light on the value of different approaches to integration.
AD  - [Melendez-Torres, G. J.] Cardiff Univ, Sch Social Sci, DECIPHer, Cardiff, S Glam, Wales. [Tancred, Tara; Bonell, Christopher] London Sch Hyg &amp; Trop Med, Dept Social &amp; Environm Hlth Res, London, England. [Fletcher, Adam] Cardiff Univ, Cardiff, S Glam, Wales. [Campbell, Rona] Univ Bristol, Bristol Med Sch, DECIPHer, Bristol, Avon, England. [Thomas, James] UCL, UCL Inst Educ, EPPI Ctr, London, England.Melendez-Torres, GJ (reprint author), Cardiff Univ, Sch Social Sci, DECIPHer, Cardiff, S Glam, Wales.melendez-torresg@cardiff.ac.uk
AN  - WOS:000450417800026
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Tancred,
AU  - T.
AU  - Fletcher,
AU  - A.
AU  - Campbell,
AU  - R.
AU  - Thomas,
AU  - J.
AU  - Bonell,
AU  - C.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1136/bmjopen-2017-020793
J2  - BMJ Open
KW  - systematic review
KW  - violence
KW  - community child health
KW  - randomized controlled-trial
KW  - elementary-school students
KW  - literacy
KW  - intervention
KW  - positive action
KW  - clinical-trial
KW  - substance use
KW  - program
KW  - victimization
KW  - behavior
KW  - impacts
KW  - General &amp; Internal Medicine
L1  - internal-pdf://1235323419/Melendez-Torres-2018-Integration of academic a.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: HA6VDTimes Cited: 0Cited Reference Count: 46Melendez-Torres, G. J. Tancred, Tara Fletcher, Adam Campbell, Rona Thomas, James Bonell, ChristopherNational Institute for Health Research Public Health Research Programme [14/52/15]; Centre for the Development and Evaluation of Complex Interventions for Public Health Improvement (DECIPHer), a UKCRC Public Health Research Centre of Excellence; British Heart Foundation [MR/KO232331/1]; Cancer Research UK; Economic and Social Research Council; Medical Research Council; Welsh Government; Wellcome Trust under the UK Clinical Research CollaborationThis work was funded through National Institute for Health Research Public Health Research Programme grant 14/52/15. The work was undertaken with the support of The Centre for the Development and Evaluation of Complex Interventions for Public Health Improvement (DECIPHer), a UKCRC Public Health Research Centre of Excellence. Joint funding (MR/KO232331/1) from the British Heart Foundation, Cancer Research UK, Economic and Social Research Council, Medical Research Council, the Welsh Government and the Wellcome Trust, under the auspices of the UK Clinical Research Collaboration, is gratefully acknowledged.01Bmj publishing groupLondon
PY  - 2018
SP  - 16
T2  - Bmj Open
TI  - Integration of academic and health education for the prevention of physical aggression and violence in young people: systematic review, narrative synthesis and intervention components analysis
UR  - &lt;Go to ISI&gt;://WOS:000450417800026
UR  - https://bmjopen.bmj.com/content/bmjopen/8/9/e020793.full.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - Community correctional sentences are administered to more juvenile offenders in North America than any other judicial sentence. Particularly prominent in juvenile corrections is intensive supervision probation and aftercare/reentry, yet the effects of these supervision-oriented interventions on recidivism are mixed. The purpose of this meta-analysis is to determine the effects of intensive supervision probation and aftercare/reentry on juvenile recidivism. An extensive search of the literature and application of strict inclusion criteria resulted in the selection of 27 studies that contributed 55 individual effect sizes. Studies were pooled based on intervention type (intensive supervision probation or aftercare/reentry) and outcome measure (alleged or convicted offenses). The pooled analyses yielded contradictory results with respect to outcome measure; in both cases, supervision had a beneficial effect on alleged offenses and negatively affected convicted offenses. These patterns across intervention type and outcome measure, as well as recommendations for future research, are discussed. (PsycINFO Database Record (c) 2019 APA, all rights reserved)
AN  - 2018-17554-006
AU  - Bouchard,
AU  - J.
AU  - Wong,
AU  - J.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0306624X17690449
L1  - internal-pdf://2005637447/Bouchard-2018-Examining the effects of intensi.pdf
PY  - 2018
SP  - 1509-1534
TI  - Examining the effects of intensive supervision and aftercare programs for at-risk youth: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2018-17554-006
VL  - 62
ER  -
TY  - JOUR
AB  - **Background**
Overly punitive responses to youth misconduct may have the unintended consequence of increasing the likelihood of future delinquency; yet, overly lenient responses may fail to serve as a corrective for the misbehavior. Police diversion schemes are a collection of strategies police can apply as an alternative to court processing of youth. Police‐initiated diversion schemes aim to reduce reoffending by steering youth away from deeper penetration into the criminal justice system and by providing an alternative intervention that can help youth address psychosocial development or other needs that contribute to their problem behavior.

**Objectives**
The objective of this review was to synthesize the evidence on the effectiveness of pre‐court interventions involving police warning or counseling and release, and cautioning schemes in reducing delinquent behavior.

**Search methods**
A combination of 26 databases and websites were searched. References of relevant reviews were also scanned to identify studies. We also consulted with experts in the field. Searches were executed by two reviewers and conducted between August 2016 and January 2017.

**Selection criteria**
Only experimental and quasi‐experimental designs were eligible for this review. All quasi‐experimental designs must have had a comparison group similar to the police diversion intervention group with respect to demographic characteristics and prior involvement in delinquent behavior (i.e., at similar risk for future delinquent behavior). Additionally, studies must have included youth participants between 12 and 17 years of age who either underwent traditional system processing or were diverted from court processing through a police‐led diversion program. Studies were also eligible if delinquency‐related outcomes, including official and non‐official (self‐report or third‐party reporting) measures of delinquency were reported.

**Data collection and analysis**
This study used meta‐analysis to synthesize results across studies. This method involved systematic coding of study features and conversion of study findings into effect sizes reflecting the direction and magnitude of any police‐led diversion effect. There were 19 independent evaluations across the 14 primary documents coded for this review. From this, we coded 67 effect sizes of delinquent behavior post diversion across 31 diversion‐traditional processing comparisons. We analyzed these comparisons using two approaches. The first approach selected a single effect size per comparison based on a decision rule and the second used all 67 effect sizes, nesting these within comparison condition and evaluation design.

**Results**
The general pattern of evidence is positive, suggesting that police‐led diversion modestly reduces future delinquent behavior of low‐risk youth relative to traditional processing.

**Authors&#039; conclusions**
The findings from this systematic review support the use of police‐led diversion for low‐risk youth with limited or no prior involvement with the juvenile justice system. Thus, police departments and policy‐makers should consider diversionary programs as part of the mix of solutions for addressing youth crime.
AU  - Wilson,
AU  - D.
AU  - B.
AU  - Brennan,
AU  - I.
AU  - Olaghere,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.4073/csr.2018.5
L1  - internal-pdf://1485293147/CJCG_0287_Wilson_Police_diversion.pdf
PY  - 2018
T2  - Campbell Systematic Reviews
TI  - Police-initiated diversion for youth to prevent future delinquent behavior: a systematic review
VL  - 14
ER  -
TY  - JOUR
AB  - **Background: **
Depression and anxiety are the most common mental disorders in children and adolescents. Bibliotherapy is a treatment using written materials for mental health problems. Its main advantages are ease of use, low cost, low staffing demands, and greater privacy. Yet few meta-analyses have focused on the effect of bibliotherapy on depression and anxiety disorders in children and adolescents. 

**Methods: **
We included randomized controlled trials comparing bibliotherapy with control conditions for depression and anxiety in children and adolescents (aged &lt;= 18 years). Five electronic databases (PubMed, Embase, Cochrane, Web of Science, and PsycINFO) were searched from inception to January 2017. Efficacy was defined as mean change scores in depression and anxiety symptoms. Acceptability was defined as the proportion of participants who discontinued the treatment. Random effects model was used. An intention-to-treat analysis was conducted. 

**Results: **
Eight studies with 979 participants were selected. At posttreatment, bibliotherapy was significantly more effective than the control conditions in reducing the symptoms of depression or anxiety (standardized mean difference, -0.52; 95% confidence interval [CI], -0.89 to -0.15). Bibliotherapy did not have statistically significantly more all-cause discontinuations than controls (risk ratios, 1.66; 95% CI, 0.93 to 2.95). We also performed subgroup analyses for efficacy outcomes in different categories (types of disorder, mean age, control conditions, and parental involvement) of studies and found that bibliotherapy has been more effective in depressive adolescents. 

**Limitations: **
Limited studies were eligible in this review and hence there was potential publication bias. 

**Conclusion:**
According to the findings in this review, bibliotherapy may be more beneficial in treating depression in adolescents, but shows less robust effects for anxiety in children. Further well-defined clinical studies should be performed to confirm these outcomes. 

(PsycINFO Database Record (c) 2018 APA, all rights reserved)
AN  - 2018-04822-001
AU  - Yuan,
AU  - S.
AU  - Zhou,
AU  - X.
AU  - Zhang,
AU  - Y.
AU  - Zhang,
AU  - H.
AU  - Pu,
AU  - J.
AU  - Yang,
AU  - L.
AU  - Liu,
AU  - L.
AU  - Jiang,
AU  - X.
AU  - Xie,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
L1  - internal-pdf://3132024132/Yuan_2018.pdf
PY  - 2018
T2  - Neuropsychiatric Disease and Treatment Vol 14 2018, ArtID 353-365
TI  - Comparative efficacy and acceptability of bibliotherapy for depression and anxiety disorders in children and adolescents: A meta-analysis of randomized clinical trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2018-04822-001
VL  - 14
ER  -
TY  - JOUR
AB  - To systematically review and quantitatively synthesize the evidence for the impact of parenting interventions for incarcerated parents on parenting knowledge and skills, parent well-being, and quality of the parent-child relationship. 

A systematic search of 19 published and unpublished literature sources was conducted between June and July 2015 (with no date, language, document type, or geographical restrictions). Studies were included if they: (a) utilized a sample of parents who completed a parenting intervention in an incarceration setting; (b) measured parenting knowledge and skills, parent well-being, or quality of the parent-child relationship as outcome measures; and (c) employed a randomized controlled trial or quasi-experimental design with no treatment, waitlist control, or treatment-as-usual as the comparison condition. 

Two review authors independently determined study eligibility and extracted data from eligible studies, which included rating the risk of bias for each eligible study. Meta-analysis was used to synthesize standardized effect sizes, and subgroup analyses were used to examine the moderating effect of parent gender, level of child involvement, and research design. Twenty-two studies were eligible for inclusion in the review; however, only 16 studies (N = 2292) reported sufficient data for inclusion in the meta-analyses. 

Parenting interventions were more effective at post-intervention for improving parenting knowledge and skills than no treatment, waitlist control, or treatment-as-usual [standardized mean difference (SMD) = 0.68, 95% confidence interval (CI) 0.28, 1.06] and quality of the parent-child relationship (SMD = 0.27, 95% CI 0.02, 0.51), but not for improving parent well-being (SMD = 0.14, 95% CI -0.03, 0.30). There was significant heterogeneity across effect sizes for both parenting knowledge and skills and quality of the parent-child relationship outcome domains. 

There were no statistically significant differences between subgroups, and the effectiveness of parenting interventions was not maintained at follow-up time-points. Existing evidence suggests small to moderate effectiveness for parenting interventions during incarceration at close to intervention completion. Further methodologically robust research is required to more confidently establish the effectiveness of parenting programs both in the short-term and in the post-release period.
AD  - [Armstrong, Eleanor; Eggins, Elizabeth; Reid, Natasha; Dawe, Sharon] Griffith Univ, Sch Appl Psychol, Brisbane, Qld, Australia. [Armstrong, Eleanor; Eggins, Elizabeth; Reid, Natasha; Dawe, Sharon] Menzies Hlth Inst Queensland, Brisbane, Qld, Australia. [Harnett, Paul] Univ Queensland, Sch Psychol, Brisbane, Qld, Australia. [Dawe, Sharon] Griffith Univ, Clin Psychol, Griffith, Qld, Australia.Dawe, S (reprint author), Griffith Univ, Sch Appl Psychol, Brisbane, Qld, Australia.; Dawe, S (reprint author), Menzies Hlth Inst Queensland, Brisbane, Qld, Australia.s.dawe@griffith.edu.au
AN  - WOS:000442514500002
AU  - Armstrong,
AU  - E.
AU  - Eggins,
AU  - E.
AU  - Reid,
AU  - N.
AU  - Harnett,
AU  - P.
AU  - Dawe,
AU  - S.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s11292-017-9290-6
J2  - J. Exp. Criminol.
KW  - Incarcerated parents
KW  - Meta-analysis
KW  - Parenting
KW  - Parent-child
KW  - relationship
KW  - Parenting programs
KW  - Systematic review
KW  - randomized controlled-trial
KW  - mental-health
KW  - maternal incarceration
KW  - training-program
KW  - clinical-trials
KW  - united-states
KW  - mothers
KW  - prison
KW  - fathers
KW  - women
KW  - Criminology &amp; Penology
L1  - internal-pdf://1767962829/Armstrong-2018-Parenting interventions for inc.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GR3SFTimes Cited: 0Cited Reference Count: 107Armstrong, Eleanor Eggins, Elizabeth Reid, Natasha Harnett, Paul Dawe, Sharon0SpringerDordrecht1572-8315
PY  - 2018
SP  - 279-317
T2  - Journal of Experimental Criminology
TI  - Parenting interventions for incarcerated parents to improve parenting knowledge and skills, parent well-being, and quality of the parent-child relationship: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000442514500002
UR  - https://link.springer.com/article/10.1007%2Fs11292-017-9290-6
VL  - 14
ER  -
TY  - JOUR
AB  - **AIM:**
To explore the effectiveness of preoperative psychological preparation programmes aimed to reduce paediatric preoperative anxiety and the potential factors that could have an impact on parent and children&#039;s acceptance of such interventions.

**BACKGROUND: **
Various preoperative psychological preparation programmes are available to address paediatric preoperative anxiety. No mixed-method review has been conducted to explore the effectiveness and acceptability of these programmes.

**DESIGN:**
A mixed-method systematic review.

**DATA SOURCES: **
Seven bibliographic databases were searched from inception to September 2016, complemented by hand searching of key journals, the reference lists of relevant reviews, search for grey literature and the contacting of associated experts.

**REVIEW METHODS:** 
The review process was conducted based on the framework developed by the Evidence for Policy and Practice Information and Co-ordinating Centre. A narrative summary and a thematic synthesis were developed to synthesise the quantitative and qualitative data respectively, followed by a third synthesis to combine the previous syntheses.

**RESULTS: **
Nineteen controlled trials and eleven qualitative studies were included for data synthesis. The controlled trials reveal that educational multimedia applications and web-based programmes may reduce paediatric preoperative anxiety, while the effectiveness of therapeutic play and books remains uncertain. Qualitative studies showed parent-child dyads seek different levels of information.

**CONCLUSIONS: **
Providing matched information provision to each parent and child, actively involving children and their parents and teaching them coping skills, may be the essential hallmarks of a successful preoperative psychological preparation. Further research is necessary to confirm the effectiveness of therapeutic play and books. 

This article is protected by copyright. All rights reserved.
AD  - Dai, Ying. Guangzhou Women and Children&#039;s Medical Center, No.9 Jinsui Road, Guangzhou, 510623, China.Livesley, Joan. School of Nursing, Midwifery, Social Work&amp; Social Sciences, University of Salford, Manchester, M5 4WT, UK.
AN  - 29754399
AU  - Dai,
AU  - Y.
AU  - Livesley,
AU  - J.
DA  - May 13
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jan.13713
DP  - Ovid Technologies
J2  - J Adv Nurs
L1  - internal-pdf://4167501136/Dai-2018-A mixed-method systematic review of t.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingMayDai, YingLivesley, Joan
PY  - 2018
SP  - 13
T2  - Journal of Advanced Nursing
TI  - A mixed-method systematic review of the effectiveness and acceptability of preoperative psychological preparation programmes to reduce paediatric preoperative anxiety in elective surgery
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29754399
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29754399&amp;id=doi:10.1111%2Fjan.13713&amp;issn=0309-2402&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Journal+of+Advanced+Nursing&amp;atitle=A+mixed-method+systematic+review+of+the+effectiveness+and+acceptability+of+preoperative+psychological+preparation+programmes+to+reduce+paediatric+preoperative+anxiety+in+elective+surgery.&amp;aulast=Dai&amp;pid=%3Cauthor%3EDai+Y%3C%2Fauthor%3E%3CAN%3E29754399%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/jan.13713
VL  - 13
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
The present review aimed to assess the quality, content and evidence of efficacy of universally delivered (to all pupils aged 5-16 years), school-based, mental health interventions designed to promote mental health/well-being and resilience, using a validated outcome measure and provided within the UK in order to inform UK schools-based well-being implementation.

**DESIGN: **
A systematic review of published literature set within UK mainstream school settings.

**DATA SOURCES: **
Embase, CINAHL, MEDLINE, PsycINFO, PsychArticles, ASSIA and Psychological and Behavioural Sciences published between 2000 and April 2016.

**ELIGIBILITY CRITERIA: **
Published in English; universal interventions that aimed to improve mental health/emotional well-being in a mainstream school environment; school pupils were the direct recipients of the intervention; pre-post design utilised allowing comparison using a validated outcome measure.

**DATA EXTRACTION AND SYNTHESIS: **
12 studies were identified including RCTs and non-controlled pre-post designs (5 primary school based, 7 secondary school based). A narrative synthesis was applied with study quality check. 

**RESULTS: **
Effectiveness of school-based universal interventions was found to be neutral or small with more positive effects found for poorer quality studies and those based in primary schools (pupils aged 9-12 years). Studies varied widely in their use of measures and study design. Only four studies were rated &#039;excellent&#039; quality. Methodological issues such as small sample size, varying course fidelity and lack of randomisation reduced overall study quality. Where there were several positive outcomes, effect sizes were small, and methodological issues rendered many results to be interpreted with caution. Overall, results suggested a trend whereby higher quality studies reported less positive effects. The only study that conducted a health economic analysis suggested the intervention was not cost-effective.

**CONCLUSIONS: **
The current evidence suggests there are neutral to small effects of universal, school-based interventions in the UK that aim to promote emotional or mental well-being or the prevention of mental health difficulties. Robust, long-term methodologies need to be pursued ensuring adequate recording of fidelity, the use of validated measures sensitive to mechanisms of change, reporting of those lost to follow-up and any adverse effects. Further high-quality and large-scale research is required across the UK in order to robustly test any long-term benefits for pupils or on the wider educational or health system.
AD  - Mackenzie, Karen. Psychological Services NHS Ayrshire and Arran, Ayrshire Central Hospital, Irvine, UK.Williams, Christopher. Mental Health and Wellbeing, University of Glasgow, Glasgow, UK.
AN  - 30196267
AU  - Mackenzie,
AU  - K.
AU  - Williams,
AU  - C.
DA  - Sep 08
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmjopen-2018-022560
DP  - Ovid Technologies
J2  - BMJ Open
L1  - internal-pdf://3848803521/Mackenzie-2018-Universal, school-based interve.pdf
LA  - English
N1  - Mackenzie, KarenWilliams, Christopher
PY  - 2018
SP  - e022560
T2  - BMJ Open
TI  - Universal, school-based interventions to promote mental and emotional well-being: what is being done in the UK and does it work? A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30196267
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129100/pdf/bmjopen-2018-022560.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **OBJECTIVES:** 
Research suggests Animal Assisted Interventions (AAI) reduce negative outcomes in medical settings, but quantitative examinations of their effects on medical outcomes such as pain, anxiety, and distress are lacking.

**DESIGN:** 
A comprehensive literature search and meta-analysis were conducted in which 22 studies (13 child, 9 adult) met inclusion criteria. Both intervention versus control and intervention pre-post effect sizes were computed using a random effects model.

**RESULTS:** 
The overall intervention versus control effect size was large and significant (d = 1.65, 95% CI=0.46-2.832). Similarly, the pre-post effect size was large and significant (d=2.19, 95% CI=0.74-3.64).

**CONCLUSIONS:** 
The results of this meta-analysis indicate that AAI can yield large effects across a number of medically relevant outcomes. There is, however, substantial methodological variation across studies and more randomized clinical trials with stronger methodological controls are needed to establish the effectiveness of AAI compared to other interventions.
AD  - Waite, Tabitha C. Psychology Department, Bowling Green State University, Bowling Green, OH, 43403, USA. Electronic address: waitet@bgsu.edu.Hamilton, Lindsay. Psychology Department, Bowling Green State University, Bowling Green, OH, 43403, USA.O&#039;Brien, William. Psychology Department, Bowling Green State University, Bowling Green, OH, 43403, USA.
AN  - 30396626
AU  - Waite,
AU  - T.
AU  - C.
AU  - Hamilton,
AU  - L.
AU  - O&#039;Brien,
AU  - W.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ctcp.2018.07.006
DP  - Ovid Technologies
J2  - Complement Ther Clin Pract
L1  - internal-pdf://0754683724/Waite-2018-A meta-analysis of Animal Assisted.pdf
LA  - English
N1  - Waite, Tabitha CHamilton, LindsayO&#039;Brien, WilliamS1744-3881(18)30052-5
PY  - 2018
SP  - 49-55
T2  - Complementary Therapies in Clinical Practice
TI  - A meta-analysis of Animal Assisted Interventions targeting pain, anxiety and distress in medical settings
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30396626
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30396626&amp;id=doi:10.1016%2Fj.ctcp.2018.07.006&amp;issn=1744-3881&amp;isbn=&amp;volume=33&amp;issue=&amp;spage=49&amp;pages=49-55&amp;date=2018&amp;title=Complementary+Therapies+in+Clinical+Practice&amp;atitle=A+meta-analysis+of+Animal+Assisted+Interventions+targeting+pain%2C+anxiety+and+distress+in+medical+settings.&amp;aulast=Waite&amp;pid=%3Cauthor%3EWaite+TC%3C%2Fauthor%3E%3CAN%3E30396626%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 33
ER  -
TY  - JOUR
AB  - This study provides a synthesis of meta-analyses and systematic reviews on non-pharmacological treatments for childhood aggression. Treatments referred to universal prevention, selective prevention, indicated prevention, or intervention (Mrazek and Haggerty, 1994). 

Seventy-two meta-analyses and systematic reviews met the inclusion criteria. We describe their characteristics, effect sizes across types of treatments, and the effects of various moderators. For universal and selective prevention, effects were mostly absent or small; for indicated prevention and interventions, effects were mostly small or medium. 

Only two moderators had a positive effect on treatment effectiveness, namely pre-test levels of aggression and parental involvement. These results identified similarities between indicated prevention and intervention treatments, on the one hand, and universal prevention and selective prevention, on the other. 

Our findings suggest that research distinguishing between targets of treatments (i.e., factors associated with childhood aggression vs. present aggressive behaviors) would be promising. Moreover, to further increase effectiveness of treatments for childhood aggression, individual differences warrant scientific attention. 

Copyright &copy; 2018 The Authors
AD  - (Hendriks, Bartels, Finkenauer) Department of Biological Psychology, Vrije Universiteit Amsterdam, van den Boechorststraat 1, Amsterdam, BT 1081, Netherlands (Hendriks, Bartels) Amsterdam Public Health Research Institute, Amsterdam, Netherlands (Colins) Department of Child and Adolescent Psychiatry, Leiden University Medical Centre, Endegeesterstraatweg 27, Oegstgeest, AK 2342, Netherlands (Finkenauer) Interdisciplinary Social Sciences: Youth Studies, Utrecht University, Faculty of Social and Behavioural Sciences, Martinus J. Langeveld Building, Heidelberglaan 1, Utrecht, CH 3584, NetherlandsA.M. Hendriks, Department of Biological Psychology, Vrije Universiteit Amsterdam, van den Boechorststraat 1, Amsterdam, BT 1081, Netherlands. E-mail: a.m.hendriks@vu.nl
AN  - 2000626202
AU  - Hendriks,
AU  - A.
AU  - M.
AU  - Bartels,
AU  - M.
AU  - Colins,
AU  - O.
AU  - F.
AU  - Finkenauer,
AU  - C.
DA  - August
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.neubiorev.2018.03.021
DP  - Ovid Technologies
KW  - Childhood aggression
KW  - Intervention
KW  - Meta-analysis
KW  - Prevention
KW  - Systematic review
KW  - age
KW  - aggression
KW  - behavior disorder/pc [Prevention]
KW  - behavior disorder/su [Surgery]
KW  - childhood disease/pc [Prevention]
KW  - childhood disease/su [Surgery]
KW  - clinical effectiveness
KW  - clinical practice
KW  - clinical research
KW  - effect size
KW  - gender
KW  - human
KW  - meta analysis
KW  - preventive health service
KW  - review
KW  - risk factor
KW  - social status
L1  - internal-pdf://3888057367/Hendriks-2018-Childhood aggression_ A synthesi.pdf
LA  - English
M3  - Review
PY  - 2018
SP  - 278-291
T2  - Neuroscience and Biobehavioral Reviews
TI  - Childhood aggression: A synthesis of reviews and meta-analyses to reveal patterns and opportunities for prevention and intervention strategies
UR  - http://www.elsevier.com/locate/neubiorev
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexa&amp;AN=2000626202
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.neubiorev.2018.03.021&amp;issn=0149-7634&amp;isbn=&amp;volume=91&amp;issue=&amp;spage=278&amp;pages=278-291&amp;date=2018&amp;title=Neuroscience+and+Biobehavioral+Reviews&amp;atitle=Childhood+aggression%3A+A+synthesis+of+reviews+and+meta-analyses+to+reveal+patterns+and+opportunities+for+prevention+and+intervention+strategies&amp;aulast=Hendriks&amp;pid=%3Cauthor%3EHendriks+A.M.%3C%2Fauthor%3E%3CAN%3E2000626202%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S0149763417309454/1-s2.0-S0149763417309454-main.pdf?_tid=25d71078-bb55-4d68-b42b-3ca0d9583475&amp;acdnat=1539256965_c1b8d19091c1b564f24bf57e7d8449cf
VL  - 91
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
Childhood and adolescent mental health problems are a serious and growing concern worldwide. Research suggests that psychotherapy can have a significant and positive impact on children and adolescents with mental health problems, such as anxiety disorders, depression and conduct disorders. Client feedback tools serve as a method of monitoring clients&#039; progress and providing feedback from clients to therapists during the therapeutic process. These tools may help to enhance clinicians&#039; decision-making by allowing them to adapt their treatment plans as the therapy progresses, resulting in a reduction of treatment failures. Research has shown that client feedback tools have a positive effect on adults&#039; psychotherapy. This review addresses whether feedback tools in child and adolescent therapy could help therapists to better treat their young clients.

**OBJECTIVES:**
To assess the effects of client feedback in psychological therapy on child and adolescent mental health outcomes.

**SEARCH METHODS:**
We searched the Cochrane Common Mental Disorders Controlled Trials Register (CCMDCTR, Studies and References), the Cochrane Central Register of Controlled Trials (CENTRAL), Ovid MEDLINE (1946-), Embase (1974-) and PsycINFO (1967-) to 3 April 2018. We did not apply any restriction on date, language or publication status to the search.

**SELECTION CRITERIA:**
We included randomised controlled trials (RCTs) that compared client feedback to no client feedback in psychological therapies for children and adolescents.

**DATA COLLECTION AND ANALYSIS:**
Two review authors independently assessed references for inclusion eligibility and extracted outcome, risk of bias and study characteristics data into customised forms. We contacted study authors to obtain missing data. We analysed dichotomous data using risk ratios (RRs) and calculated their 95% confidence intervals (CIs). For continuous data, we calculated mean differences (MDs), or standardised mean differences (SMDs) if different scales were used to measure the same outcome. We used a random-effects model for all analyses.

**MAIN RESULTS:**
We included six published RCTs, conducted in the USA (5 RCTs) and Israel (1 RCT), with 1097 children and adolescents (11 to 18 years old), in the review.We are very uncertain about the effect of client feedback on improvement of symptoms, as reported by youth in the short term because we considered evidence to be of very low-certainty due to high risk of bias and very serious inconsistency in the effect estimates from the different studies. Similarly, we are very uncertain about the effect of client feedback on treatment acceptability, due to high risk of bias, imprecision in the results, and indirectness of measuring the outcome (RR 1.08, 95% CI 0.73 to 1.61; 2 studies, 237 participants; very low-certainty).Overall, most studies reported and carried out randomisation and allocation concealment adequately. None of the studies were blinded or attempted to blind participants and personnel and were at high risk of performance bias, and only one study had blind outcome assessors. All of the studies were at high or unclear risk of attrition bias mainly due to poor, non-transparent reporting of participants&#039; flow through the studies.

**AUTHORS&#039; CONCLUSIONS:**
Due to the paucity of high-quality data and considerable inconsistency in results from different studies, there is currently insufficient evidence to reach any firm conclusions regarding the role of client feedback in psychological therapies for children and adolescents with mental health problems, and further research on this important topic is needed.Future studies should avoid risks of performance, detection and attrition biases, as seen in the studies included in this review. Studies from countries other than the USA are needed, as well as studies including children younger than 10 years.
AU  - Bergman,
AU  - H.
AU  - Kornør,
AU  - H.
AU  - Nikolakopoulou,
AU  - A.
AU  - Hanssen‐Bauer,
AU  - K.
AU  - Soares‐Weiser,
AU  - K.
AU  - Tollefsen,
AU  - T.
AU  - K.
AU  - Bjørndal,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD011729.pub2.
L1  - internal-pdf://1674041504/Bergman-2018-Client feedback in psychological.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Client feedback in psychological therapy for children and adolescents with mental health problems
ER  -
TY  - JOUR
AB  - Cognitive behavioral therapies (CBT) for youth with anxiety, traumatic stress, and depression have demonstrated strong effects in individual studies and meta-analyses. Relatively more attention has been given to posttreatment effects, though, and assessment of follow-up effects has been limited at the meta-analytic level. 

The current meta-analysis aimed to (a) examine the effects of youth CBT at posttreatment, 1-month, 3-month, 6-month, 1-year, and long-term (2 + years) follow-up as well as (b) identify research-related variables (e.g., measure respondent type) that relate to effects. Using a random effects model across 110 child and adolescent CBT groups, within-group effect sizes were large at posttreatment (g = 1.24) and from 1-month through long-term follow-up (g = 1.23-1.82), and effect sizes did not significantly differ by treatment target (i.e., anxiety, traumatic stress, depression). 

However, availability of outcome data for effect sizes diminished across later follow-up assessments. Moreover, effect sizes were significantly associated with outcome respondent type across assessment timing, with outcome measures from caregiver and youth respondents associated with smaller effect sizes (B = -0.97, p &lt; 0.001) relative to outcome measures that were evaluator-reported. 

Results provide initial support for the durability of treatment effects for youth CBTs and highlight the importance of some confounding variables. Implications for improving treatment research standards and prioritizing assessment of long-term follow-up assessment are discussed. 

Copyright &copy; 2018
AD  - (Rith-Najarian, Mesri, Park, Sun, Chavira, Chorpita) University of California, Los Angeles, United StatesL.R. Rith-Najarian, University of California, Los Angeles 90095, United States. E-mail: leslierrn@ucla.edu
AN  - 2000898583
AU  - Rith-Najarian,
AU  - L.
AU  - R.
AU  - Mesri,
AU  - B.
AU  - Park,
AU  - A.
AU  - L.
AU  - Sun,
AU  - M.
AU  - Chavira,
AU  - D.
AU  - A.
AU  - Chorpita,
AU  - B.
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.beth.2018.05.006
DP  - Ovid Technologies
KW  - anxiety
KW  - cognitive behavioral therapy
KW  - depression
KW  - traumatic stress
KW  - youth
KW  - adolescent
KW  - article
KW  - attention
KW  - caregiver
KW  - child
KW  - confounding variable
KW  - controlled study
KW  - effect size
KW  - female
KW  - follow up
KW  - human
KW  - juvenile
KW  - male
KW  - meta analysis
KW  - outcome assessment
KW  - posttraumatic stress disorder
L1  - internal-pdf://2004034782/Rith-Najarian-2018-Durability of Cognitive Beh.pdf
LA  - English
M3  - In Press
N1  - Using Smart Source ParsingDate of Publication: 2018
PY  - 2018
T2  - Behavior Therapy.
TI  - Durability of Cognitive Behavioral Therapy Effects for Youth and Adolescents With Anxiety, Depression, or Traumatic Stress:A Meta-Analysis on Long-Term Follow-Ups
UR  - http://www.journals.elsevier.com/behavior-therapy/
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2000898583
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.beth.2018.05.006&amp;issn=0005-7894&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Behavior+Therapy&amp;atitle=Durability+of+Cognitive+Behavioral+Therapy+Effects+for+Youth+and+Adolescents+With+Anxiety%2C+Depression%2C+or+Traumatic+Stress%3AA+Meta-Analysis+on+Long-Term+Follow-Ups&amp;aulast=Rith-Najarian&amp;pid=%3Cauthor%3ERith-Najarian+L.R.%3C%2Fauthor%3E%3CAN%3E2000898583%3C%2FAN%3E%3CDT%3EArticle+In+Press%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S0005789418300650/1-s2.0-S0005789418300650-main.pdf?_tid=2beeab22-994d-468b-abaf-bcbb155d27ca&amp;acdnat=1539257188_e71b57140b68039eb385e7ff67a356a2
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Children and young people (CYP) with cancer undergo painful and distressing procedures. We aimed to systematically review the effectiveness of nonpharmacological interventions to reduce procedural anxiety in CYP.

**METHODS: **
Extensive literature searches sought randomised controlled trials that quantified the effect of any nonpharmacological intervention for procedural anxiety in CYP with cancer aged 0 to 25. Study selection involved independent title and abstract screening and full text screening by two reviewers. Anxiety, distress, fear, and pain outcomes were extracted from included studies. Where similar intervention, comparator, and outcomes presented, meta-analysis was performed, producing pooled effect sizes (Cohen&#039;s d) and 95% confidence intervals (95% CI). All other data were narratively described. Quality and risk of bias appraisal was performed, based on the Cochrane risk of bias tool.

**RESULTS: **
Screening of 11 727 records yielded 56 relevant full texts. There were 15 included studies, eight trialling hypnosis, and seven nonhypnosis interventions. There were large, statistically significant reductions in anxiety and pain for hypnosis, particularly compared with treatment as usual (anxiety: d = 2.30; 95% CI, 1.30-3.30; P &lt; .001; pain: d = 2.16; 95% CI, 1.41-2.92; P &lt; .001). Evidence from nonhypnosis interventions was equivocal, with some promising individual studies. There was high risk of bias across included studies limiting confidence in some positive effects.

**CONCLUSIONS: **
Evidence suggests promise for hypnosis interventions to reduce procedural anxiety in CYP undergoing cancer treatment. These results largely emerge from one research group, therefore wider research is required. Promising evidence for individual nonhypnosis interventions must be evaluated through rigorously conducted randomised controlled trials.
AD  - Nunns, Michael. University of Exeter Medical School, University of Exeter, Exeter, UK.Mayhew, Dominic. University of Exeter Medical School, University of Exeter, Exeter, UK.Ford, Tamsin. University of Exeter Medical School, University of Exeter, Exeter, UK.Rogers, Morwenna. University of Exeter Medical School, University of Exeter, Exeter, UK.Curle, Christine. Devon Integrated Children&#039;s Service, Exeter, UK.Logan, Stuart. University of Exeter Medical School, University of Exeter, Exeter, UK.Moore, Darren. University of Exeter Medical School, University of Exeter, Exeter, UK.
AN  - 29714037
AU  - Nunns,
AU  - M.
AU  - Mayhew,
AU  - D.
AU  - Ford,
AU  - T.
AU  - Rogers,
AU  - M.
AU  - Curle,
AU  - C.
AU  - Logan,
AU  - S.
AU  - Moore,
AU  - D.
DA  - Apr 30
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/pon.4749
DP  - Ovid Technologies
J2  - Psychooncology
L1  - internal-pdf://2886931573/Nunns-2018-Effectiveness of nonpharmacological.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingAprNunns, MichaelMayhew, DominicFord, TamsinRogers, MorwennaCurle, ChristineLogan, StuartMoore, Darren
PY  - 2018
SP  - 30
T2  - Psycho Oncology
TI  - Effectiveness of nonpharmacological interventions to reduce procedural anxiety in children and adolescents undergoing treatment for cancer: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29714037
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29714037&amp;id=doi:10.1002%2Fpon.4749&amp;issn=1057-9249&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Psycho-Oncology&amp;atitle=Effectiveness+of+nonpharmacological+interventions+to+reduce+procedural+anxiety+in+children+and+adolescents+undergoing+treatment+for+cancer%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Nunns&amp;pid=%3Cauthor%3ENunns+M%3C%2Fauthor%3E%3CAN%3E29714037%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1002/pon.4749
VL  - 30
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) is a chronic developmental disorder affecting 3-7% of children. In light of the growing utilization of yoga, mindfulness, and meditation in ADHD populations and potential benefits it has on ADHD symptoms, executive function deficits, and social functioning, we sought to evaluate these interventions for youth with ADHD. 

The primary aim of this review paper is to identify the efficacy of these programs for the treatment of youth with ADHD through a systematic review and meta-analysis. A systematic literature search was conducted in the following electronic databases: PsychINFO, ERIC, PubMed, and MEDLINE. Studies were included in the meta-analytic review if participants were between 5-17 years old, had a diagnosis of ADHD or met symptom threshold on psychometrically-validated measure of ADHD symptoms, was a treatment outcome study, and was published in a peer-reviewed English-language journal. 

The effect sizes of eleven studies demonstrate that yoga, mindfulness-based interventions, and/or meditation had a statistically significant effect on the outcomes of ADHD symptoms, hyperactivity, and inattention (parent and teacher report), as well as parent-child relationship, executive functioning, on-task behavior, parent stress, and parent trait-mindfulness (p &lt; 0.05). The effect sizes range from small to large effects across these outcomes. 

Considerable risk for bias was found across studies. Given significant methodological limitations of the literature, positive effect sizes found in studies should be interpreted with caution; these interventions should not be considered first-line interventions for ADHD. However, preliminary findings suggest yoga, mindfulness, and meditation may be beneficial for youth with ADHD, but extensive research is required to validate the efficacy of these interventions.
AD  - [Chimiklis, Alyssa L.] CUNY, Grad Ctr, Dept Psychol, New York, NY 10016 USA. [Chimiklis, Alyssa L.; Dahl, Victoria; Spears, Angela P.; Goss, Kelly; Fogarty, Katie; Chacko, Anil] NYU, Dept Appl Psychol, New York, NY 10003 USA.Chimiklis, AL (reprint author), CUNY, Grad Ctr, Dept Psychol, New York, NY 10016 USA.; Chimiklis, AL (reprint author), NYU, Dept Appl Psychol, New York, NY 10003 USA.achimiklis@gmail.com
AN  - WOS:000444720100009
AU  - Chimiklis,
AU  - A.
AU  - L.
AU  - Dahl,
AU  - V.
AU  - Spears,
AU  - A.
AU  - P.
AU  - Goss,
AU  - K.
AU  - Fogarty,
AU  - K.
AU  - Chacko,
AU  - A.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10826-018-1148-7
J2  - J. Child Fam. Stud.
KW  - Attention deficit/hyperactivity-disorder
KW  - ADHD
KW  - Yoga
KW  - Mindfulness
KW  - Meditation
KW  - attention-deficit/hyperactivity disorder
KW  - randomized controlled-trial
KW  - executive function
KW  - children
KW  - adolescents
KW  - outcomes
KW  - anxiety
KW  - definition
KW  - impairment
KW  - behavior
KW  - Family Studies
KW  - Psychology
KW  - Psychiatry
L1  - internal-pdf://3196256757/Chimiklis-2018-Yoga, Mindfulness, and Meditati.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GT7PHTimes Cited: 0Cited Reference Count: 69Chimiklis, Alyssa L. Dahl, Victoria Spears, Angela P. Goss, Kelly Fogarty, Katie Chacko, Anil0SpringerNew york1573-2843
PY  - 2018
SP  - 3155-3168
T2  - Journal of Child and Family Studies
TI  - Yoga, Mindfulness, and Meditation Interventions for Youth with ADHD: Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000444720100009
UR  - https://link.springer.com/article/10.1007%2Fs10826-018-1148-7
VL  - 27
ER  -
TY  - JOUR
AB  - **Aim:** 
A systematic review and meta-analysis was conducted to examine the relationship between KMC and infant/toddler biopsychosocial outcomes. 

**Method: **
PubMed, MEDLINE (OvidSP), MEDLINE in Process (OvidSP), Embase (OvidSP), PsycINFO (OvidSP), and AMED (OvidSP) were searched. Observational studies and randomized control trials through October 2015 that investigated the association between KMC intervention and infant/toddler biopsychosocial outcomes were included. Studies with &lt;10 participants, those using skin-to-skin only during painful procedures or only on the day of birth, and those that did not report quantitative outcomes were excluded. Data were extracted by two coders and estimates were examined using random-effects. 

**Results: **
3177 studies were screened with 13 meeting inclusion criteria and representing 5 child outcomes (cognitive, motor, self-regulation, socio-emotional and temperament). Among LBW/premature neonates, KMC compared to conventional care was associated with improved infant self-regulation. Moderated effects were identified for cognitive (duration of KMC) and motor development (duration of KMC, country-level mortality ratio, and infant gender). 

**Interpretations: **
KMC administered to vulnerable neonates during a sensitive period of brain development has a lasting impact on self-regulation skills later in infancy. Further research examining the longer-term effect of KMC on cognitive and motor development, socioemotional skills, and temperament is needed. 

Copyright &copy; 2018
AD  - (Akbari) School of Early Childhood, George Brown College, Toronto, Ontario, Canada (Akbari) Atkinson Centre for Society and Child Development, Toronto, Ontario, Canada (Binnoon-Erez, Rodrigues, Ricci, Jenkins) Department of Applied Psychology and Human Development, University of Toronto, Toronto, Ontario, Canada (Schneider) Division of Neurology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada (Madigan) Alberta Children&#039;s Hospital Research Institute, Calgary, Alberta, Canada (Madigan) Department of Psychology, University of Calgary, Calgary, Alberta, CanadaE. Akbari, School of Early Childhood, George Brown College, 99 Gerrard St. East, Toronto, Ontario M5B 2L4, Canada. E-mail: emis.akbari@georgebrown.ca
AN  - 2000802048
AU  - Akbari,
AU  - E.
AU  - Binnoon-Erez,
AU  - N.
AU  - Rodrigues,
AU  - M.
AU  - Ricci,
AU  - A.
AU  - Schneider,
AU  - J.
AU  - Madigan,
AU  - S.
AU  - Jenkins,
AU  - J.
DA  - July
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.earlhumdev.2018.05.004
DP  - Ovid Technologies
KW  - article
KW  - brain development
KW  - cognitive development
KW  - controlled study
KW  - Embase
KW  - female
KW  - human
KW  - infant
KW  - information retrieval
KW  - kangaroo care
KW  - low birth weight
KW  - male
KW  - Medline
KW  - meta analysis (topic)
KW  - motor development
KW  - observational study
KW  - prematurity
KW  - psychosocial development
KW  - PsycINFO
KW  - randomized controlled trial
KW  - self concept
KW  - temperament
L1  - internal-pdf://0413393621/Akbari-2018-Kangaroo mother care and infant bi.pdf
LA  - English
PY  - 2018
SP  - 22-31
T2  - Early Human Development
TI  - Kangaroo mother care and infant biopsychosocial outcomes in the first year: A meta-analysis
UR  - http://www.elsevier.com/locate/earlhumdev
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=2000802048
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.earlhumdev.2018.05.004&amp;issn=0378-3782&amp;isbn=&amp;volume=122&amp;issue=&amp;spage=22&amp;pages=22-31&amp;date=2018&amp;title=Early+Human+Development&amp;atitle=Kangaroo+mother+care+and+infant+biopsychosocial+outcomes+in+the+first+year%3A+A+meta-analysis&amp;aulast=Akbari&amp;pid=%3Cauthor%3EAkbari+E.%3C%2Fauthor%3E%3CAN%3E2000802048%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S0378378218301476/1-s2.0-S0378378218301476-main.pdf?_tid=f822f20f-1966-410d-ae4c-b36640686e26&amp;acdnat=1533218643_b10668dd5bc4f8b4ea3271a2f12aefa2
VL  - 122
ER  -
TY  - JOUR
AB  - [Correction Notice: An Erratum for this article was reported in Vol 105 of Journal of Psychiatric Research (see record 2018-48528-008). There is an error in the second paragraph of the introduction of the original publication regarding the approved lurasidone dose range for adolescence with a depressive episode within a bipolar I disorder. The correct dose range for adolescence in the age of 10-17 years is 20-80 mg/day as monotherapy, not 40-80 mg/day as originally reported.] 

**Background:** 
Lurasidone, an azapirone derivative, is a novel second generation antipsychotic with potent binding affinity for dopamine D2, serotonin 5-HT2A, 5-HT7, 5-HT1A, and noradrenaline alpha2C receptors. This updated meta-analysis of randomized controlled trials (RCTs) examined the short-term efficacy and tolerability of lurasidone in the treatment of acute schizophrenia. 

**Methods:** 
Double-blinded RCTs reporting on the short-term effects of lurasidone were included. Standardized mean difference (SMD) with their 95% confidence interval (CI), and number needed to harm (NNH) were computed. 

**Results:** 
The meta-analysis had 8 RCTs with 16 active arms that included 2373 patients with acute schizophrenia who were randomized to either lurasidone (20-160 mg/day; n = 1570) or placebo (n = 803) groups. Lurasidone was superior to placebo with regard to change in total psychopathology [SMD: -0.34, (95%CI: -0.48, -0.20), P &lt; 0.00001], positive symptoms [SMD: -0.47, (95%CI: -0.57, -0.36), P &lt; 0.00001], negative symptoms [SMD:-0.34, (95%CI: -0.45, -0.22), P &lt; 0.00001], and general psychopathology [SMD: -0.36, (95%CI: -0.48, -0.24), P &lt; 0.00001]. Results were consistent for total psychopathology in 11 out of the 13 subgroups. Lurasidone resulted in higher weight gain [SMD: 0.15, (95% CI: 0.06, 0.24), P = 0.001] and BMI [SMD: 0.17, (95%CI: 0.07, 0.28), P = 0.002] than placebo, but the differences were not clinically significant. Lurasidone group had less frequent inefficacy (NNH = 14) and discontinuation due to any reason (NNH = 17), but was associated with more frequent vomiting, akathisia, dystonia, parkinsonism, somnolence, dizziness, sedation, nausea, and weight gain of &gt;= 7% of the initial weight (NNH = 11-50). 

**Conclusion:** 
This meta-analysis of 8 short-term studies supported the efficacy and safety of lurasidone in the acute phase of schizophrenia, particularly at the higher dose range of 80 mg/day. (PsycINFO Database Record (c) 2019 APA, all rights reserved)
AN  - 2018-30312-034
AU  - Zheng,
AU  - Wei
AU  - Cai,
AU  - Dong-Bin
AU  - Yang,
AU  - Xin-Hu
AU  - Li,
AU  - Lu
AU  - Zhang,
AU  - Qing-
AU  - E.
AU  - Ng,
AU  - Chee
AU  - H.
AU  - Ungvari,
AU  - Gabor
AU  - S.
AU  - Li,
AU  - Xian-Bin
AU  - Ning,
AU  - Yu-Ping
AU  - Xiang,
AU  - Yu-Tao
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jpsychires.2018.06.005
L1  - internal-pdf://1684467953/Zheng-2018-Short-term efficacy and tolerabilit.pdf
PY  - 2018
SP  - 244-251
T2  - Journal of Psychiatric Research
TI  - Short-term efficacy and tolerability of lurasidone in the treatment of acute schizophrenia: A meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc16&amp;AN=2018-30312-034
UR  - https://pdf.sciencedirectassets.com/271251/1-s2.0-S0022395618X00065/1-s2.0-S0022395618300979/main.pdf?X-Amz-Security-Token=AgoJb3JpZ2luX2VjELr%2F%2F%2F%2F%2F%2F%2F%2F%2F%2FwEaCXVzLWVhc3QtMSJHMEUCIQDjRUAZwzGFQq7guIrISITw6IXi8uk8lWaBK%2B%2BcbQS9agIgR1dV%2FHyjGIarmTwbPTxHVM%2BZ%2BxxvmaF%2BQvh46dOjI%2Bwq2gMIQxACGgwwNTkwMDM1NDY4NjUiDLnqoc%2FiNsQ1%2FAT7ayq3A%2FURCxoo%2FD92bNoe8dLHco5KD%2BJmXRsrkEvOBRBkZ7H5egWO277S3fbnI4DhmUMGfuNhcJlJ25eHQl5lQR77c8Vx1AsQzUnSlUbxA7qxJj5cwatkJZRAr6M7AiGQ4C%2F%2BoL7GHxqVzD%2FsQsANuW01v56ZktnIVwjKBTFrevl%2FVLYnMepE%2FB6eGknrJheRP07uORIepvk%2BAv8n3h0O3m8h2goSUZ%2FYVfPAIz7RjfmI0Kjd3cMR6df2ZXipgNDiaTzSy8HQG%2FJMmGuc9aKTbxZQaf4FzHAF9yF9tdrpKydFE9G5uyPMAbh0ZjM2uhrcoOHXGDYatIMMwTfxA0rTVYNXr7Z9m8JFO1i0BYdxHAVSgVT3KG9XK1EYy4uf7vSxVzrhlIj0blciBrmo5isPwp1SquSYcqFSIKgGFazSbZPgJYa2L%2BnT7hoJ%2BtfYMOMcYDMLoermoIdAssnEem8W1PuU4K1h08oZWDJTq0TnFVYbn10F8e875H5DJ8SfgaUxaOrdN%2F6AUg89%2BdO%2FBSthjJ5WlUF7laG4Dbtcr6FtcrLe28EjqaDNl0CVZijbfBzk9zmCMmJtCipfbZYw5pml6gU6tAE%2BxEGs73c7A%2B7CFU2O%2BY2hV0XdZoVQddTO93roIX2QKYNn%2FKshSZyHXiRVoAk%2FMSvStNeKFzQXjw8hR%2BLrEbgmPbst8lhsKRir%2B4CQ%2BEaQJwNnqReqgJiBdpyOzOm2%2FJBl%2BoiyQ6AzGdKXNcio6wktVrGbyoNvncKpWwd11TxxSqphzd9XfTWuUVdXsc7VlgbOmcb4yg41PEmXFXJcFGnfeJXjK5U4PJ%2FLygIZVYF2jDXoD7o%3D&amp;X-Amz-Algorithm=AWS4-HMAC-SHA256&amp;X-Amz-Date=20190806T101954Z&amp;X-Amz-SignedHeaders=host&amp;X-Amz-Expires=300&amp;X-Amz-Credential=ASIAQ3PHCVTY3LHOUN6D%2F20190806%2Fus-east-1%2Fs3%2Faws4_request&amp;X-Amz-Signature=167d47e08715029c26c256b1f00e87eabc821b39bd03c0e49b43dedff8244405&amp;hash=6f65e2b8778e4357a3142fda00286f016a4b011f9f2ca468851216cef6d2a894&amp;host=68042c943591013ac2b2430a89b270f6af2c76d8dfd086a07176afe7c76c2c61&amp;pii=S0022395618300979&amp;tid=spdf-00951b10-0cd1-4af6-afda-4fc3f5a71f10&amp;sid=b61fff2981e9814fa6186ad38f4780b5651cgxrqb&amp;type=client
VL  - 103
ER  -
TY  - JOUR
AB  - **Background: **
Selective mutism (SM) is a debilitating childhood anxiety disorder characterized by a persistent lack of speech in certain social settings and is considered hard to treat. Cognitive behavioral therapy (CBT) and pharmacological treatments are the best described treatments in the literature. 

**Aim: **
To test whether there is evidence on treatment based on CBT, medication or a combination of these. Methods: Systematic and critical review of the literature on CBT and/or pharmacological treatments of SM. Literature was sought on PubMed, Embase and Psycinfo in March 2017. 

**Results: **
Of the included studies, six examined CBT, seven pharmacologic treatment and two a combination of these. Using CBT 53/60 children improved symptomatically whilst respectively 55/67 and 6/7 improved using pharmacologic- and combination-treatment. 

**Conclusion: **
Pharmacologic treatment and especially CBT showed promising results supported by some degree of evidence, which combination treatment lacks. Yet small numbers, few RCTs, heterogeneous study designs, lack of consistent measures, short treatment and follow-up periods, generally limits the evidence. This needs focus in future research. 

Copyright &copy; 2018 The Nordic Psychiatric Association
AN  - 620741018
AU  - Ostergaard,
AU  - K.
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/08039488.2018.1439530
L1  - internal-pdf://3271614062/Ostergaard-2018-Treatment of selective mutism.pdf
PY  - 2018
SP  - 1-11
T2  - Nordic Journal of Psychiatry
TI  - Treatment of selective mutism based on cognitive behavioural therapy, psychopharmacology and combination therapy - a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=620741018
UR  - https://www.tandfonline.com/doi/pdf/10.1080/08039488.2018.1439530?needAccess=true
ER  -
TY  - JOUR
AB  - Behavioral activation (BA) effectively treats depression in adults, and shows promise in treating anxiety. 

Research into its application to children and adolescents is emerging. This review aimed to explore the scope of studies, current evidence of effectiveness and how the intervention has been delivered and adapted, to inform future research. 

A systematic review was undertaken searching PsycInfo, PubMed including Medline, EMBASE, and Scopus for terms relating to BA and children and adolescents. Two researchers scored abstracts for inclusion. 

Data extraction was completed by one researcher and checked by another. 19 studies were identified, across 21 published articles. 12 were case studies, with three pre-post pilot designs and four randomized-controlled trials. 

Case studies found early support for the feasibility and potential effectiveness of BA to address both anxiety and depression. The RCTs reported largely positive outcomes. 

Meta-analysis of depression scores indicated that BA may be effective; however, high heterogeneity was observed. Sample sizes to date have been small. BA has been delivered by trained therapists, doctoral trainee psychologists, social workers, or psychology graduates. Studies are uniquely in high-income settings. 

Adaptations include flexibility in content delivery, youth friendly materials, and parental involvement. There is some limited evidence to support BA as effective for young people. Feasibility and acceptability are supported. 

Fully powered trials are now required, with expansion to delivery in low- and middle-income settings, and detailed consideration of implementation issues that consider culture and environment.
AN  - 29476253
AU  - Martin,
AU  - F.
AU  - Oliver,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00787-018-1126-z
L1  - internal-pdf://1526460386/Martin-2018-Behavioral activation for children.pdf
PY  - 2018
SP  - 23
T2  - European Child &amp; Adolescent Psychiatry
TI  - Behavioral activation for children and adolescents: a systematic review of progress and promise
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29476253
UR  - https://link.springer.com/content/pdf/10.1007%2Fs00787-018-1126-z.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - **Background**
Schools are important institutions of formal social control (Maimon, Antonaccio, &amp; French, 2012). They are, apart from families, the primary social system in which individuals are socialised to follow specific codes of conduct. Violating these codes of conduct may result in some form of punishment. School punishment is normally accepted by families and students as a consequence of transgression, and in that sense school is often the place where children are first introduced to discipline, justice, or injustice (Whitford &amp; Levine-Donnerstein, 2014).

A wide range of punishments may be used in schools, from verbal reprimands to more serious actions such as detention, fixed term exclusion or even permanent exclusion from the mainstream education system. It must be said that in some way, these school sanctions resemble the penal system and its array of alternatives to punish those that break the law.

School exclusion, also known as suspension in some countries, is defined as a disciplinary sanction imposed by a responsible school authority, in reaction to students&rsquo; misbehaviour. Exclusion entails the removal of pupils from regular teaching for a period during which they are not allowed to be present in the classroom or, in more serious cases, on school premises. Based on the previous definition, this review uses school exclusion and school suspension as synonyms, unless the contrary is explicitly stated.

Most of the available research has found that exclusion correlates with subsequent negative sequels on developmental outcomes. Exclusion or suspension of students is associated with failure within the academic curriculum, aggravated antisocial behaviour, and an increased likelihood of involvement with punitive social control institutions (i.e., the Juvenile Justice System). In the long-term, opportunities for training and employment seem to be considerably reduced for those who have repeatedly been excluded. In addition to these negative correlated outcomes, previous evidence suggest that the exclusion of students involves a high economic cost for taxpayers and society.

Research from the last 20 years has concluded quite consistently that this disciplinary measure disproportionally targets males, ethnic minorities, those who come from disadvantaged economic backgrounds, and those presenting special educational needs. In other words, suspension affects the most vulnerable children in schools.

Different programmes have attempted to reduce the prevalence of exclusion. Although some of them have shown promising results, so far, no comprehensive systematic review has examined these programmes&rsquo; overall effectiveness.

**Objectives**
The main goal of the present research is to systematically examine the available evidence for the effectiveness of different types of school-based interventions aimed at reducing disciplinary school exclusion. Secondary goals include comparing different approaches and identifying those that could potentially demonstrate larger and more significant effects. The research questions underlying this project are as follows:

Do school-based programmes reduce the use of exclusionary sanctions in schools?
Are some school-based approaches more effective than others in reducing exclusionary sanctions?
Do participants&rsquo; characteristics (e.g., age, gender, ethnicity) affect the impact of school-based programmes on exclusionary sanctions in schools?
Do characteristics of the interventions, implementation, and methodology affect the impact of school-based programmes on exclusionary sanctions in schools?

**Search methods**
The authors conducted a comprehensive search to locate relevant studies reporting on the impact of school-based interventions on exclusion from 1980 onwards. Twenty-seven different databases were consulted, including databases that contained both published and unpublished literature. In addition, we contacted researchers in the field of school-exclusion for further recommendations of relevant studies; we also assessed citation lists from previous systematic and narrative reviews and research reports. Searches were conducted from September 1 to December 1, 2015.

**Selection criteria**
The inclusion and exclusion criteria for manuscripts were defined before we started our searches. To be eligible, studies needed to have: evaluated school-based interventions or school-supported interventions intended to reduce the rates of suspension; seen the interventions as an alternative to exclusion; targeted school-aged children from four to 18 in mainstream schools irrespective of nationality or social background; and reported results of interventions delivered from 1980 onwards. In terms of methodological design, we included randomised controlled trials only, with at least one experimental group and one control or placebo group.

**Data collection and analysis**
Initial searches produced a total of 42,749 references from 27 different electronic databases. After screening the title, abstract and key words, we kept 1,474 relevant hits. 22 additional manuscripts were identified through other sources (e.g., assessment of citation lists, contribution of authors). After removing duplicates, we ended up with a total of 517 manuscripts. Two independent coders evaluated each report, to determine inclusion or exclusion.

The second round of evaluation excluded 472 papers, with eight papers awaiting classification, and 37 studies kept for inclusion in meta-analysis. Two independent evaluators assessed all the included manuscripts for risk of quality bias by using EPOC tool.

Due to the broad scope of our targeted programmes, meta-analysis was conducted under a random-effect model. We report the impact of the intervention using standardised differences of means, 95% confidence intervals along with the respective forest plots. Sub-group analysis and meta-regression were used for examining the impact of the programme. Funnel plots and Duval and Tweedie&#039;s trim-and-fill analysis were used to explore the effect of publication bias.

**Results**
Based on our findings, interventions settled in school can produce a small and significant drop in exclusion rates (SMD=.30; 95% CI .20 to .41; p&lt;.001). This means that those participating in interventions are less likely to be suspended than those allocated to control/placebo groups. These results are based on measures of impact collected immediately during the first six months after treatment (on average). When the impact was tested in the long-term (i.e., 12 or more months after treatment), the effects of the interventions were not sustained. In fact, there was a substantive reduction in the impact of school-based programmes (SMD=.15; 95%CI -.06 to .35), and it was no longer statistically significant.

We ran analysis testing the impact of school-based interventions on different types of exclusion. Evidence suggests that interventions are more effective at reducing expulsion and in-school exclusion than out-of-school exclusion. In fact, the impact of intervention in out-of-school exclusion was close to zero and not statistically significant.

Nine different types of school-based interventions were identified across the 37 studies included in the review. Four of them presented favourable and significant results in reducing exclusion (i.e., enhancement of academic skills, counselling, mentoring/monitoring, skills training for teachers). Since the number of studies for each sub-type of intervention was low, we suggest that results should be treated with caution.

A priori defined moderators (i.e., participants&rsquo; characteristics, the theoretical basis of the interventions, and quality of the intervention) showed not to be effective at explaining the heterogeneity present in our results. Among three post-hoc moderators, the role of the evaluator was found to be significant: independent evaluator teams reported lower effect sizes than research teams who were also involved in the design and/or delivery of the intervention.

Two researchers independently evaluated the quality of the evidence involved in this review by using the EPOC tool. Most of the studies did not present enough information for the judgement of quality bias.

**Authors&rsquo; conclusions**
The evidence suggests that school-based interventions are effective at reducing school exclusion immediately after, and for a few months after, the intervention. Some specific types of interventions show more promising and stable results than others, namely those involving mentoring/monitoring and those targeting skills training for teachers. However, based on the number of studies involved in our calculations, we suggest that results must be cautiously interpreted. Implications for policy and practice arising from our results are discussed.
AU  - Valdebenito,
AU  - S.
AU  - Eisner,
AU  - M.
AU  - Farrington,
AU  - D.
AU  - P.
AU  - Ttofi,
AU  - M.
AU  - M.
AU  - Sutherland,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.campbellcollaboration.org/library/reducing-school-exclusion-school-based-interventions.html
PY  - 2018
T2  - Campbell Systematic Reviews
TI  - School-based interventions for reducing disciplinary school exclusion
ER  -
TY  - JOUR
AB  - Parent training (PT) is widely used with families of children with autism spectrum disorder (ASD), and its benefits for young children and their parents have been documented. 

However, no reviews have examined the use of PT within interventions delivered to older children with ASD or investigated the added benefit of including a PT component in these interventions. Therefore, the purpose of this review is to explore the state of research regarding the inclusion of PT in interventions for school-age children with ASD and to determine the value added to these interventions by including a PT component. 

Fifteen PT studies examining 622 child participants with ASD were included. Participants, interventions, and the effects of the interventions are described. 

Overall, studies demonstrated moderately positive effects for interventions that included PT. Importantly, three studies isolating the added benefit of PT demonstrated an effect size (ES) of 0.33, 95% confidence interval (CI) [0.05, 0.61], indicating the value added to interventions by including parents. More research is needed to understand the development of effective PT, its components, and how to best design these programs to benefit school-age children with ASD.
AD  - [Black, Marie E.; Therrien, William J.] Univ Virginia, Charlottesville, VA USA.Black, ME (reprint author), Univ Virginia, Curry Sch Educ, Bavaro Hall 221, Charlottesville, VA 22904 USA.meb2kn@virginia.edu
AN  - WOS:000439610000004
AU  - Black,
AU  - M.
AU  - E.
AU  - Therrien,
AU  - W.
AU  - J.
DA  - Jul-Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0741932517730645
J2  - Remedial Spec. Educ.
KW  - autism
KW  - exceptionalities
KW  - Asperger syndrome
KW  - exceptionalities
KW  - family
KW  - parental involvement
KW  - families
KW  - parents
KW  - cognitive-behavioral therapy
KW  - high-functioning autism
KW  - pervasive
KW  - developmental disorders
KW  - randomized clinical-trial
KW  - spectrum disorders
KW  - young-children
KW  - early intervention
KW  - social-skills
KW  - mental-health
KW  - anxiety
KW  - Education &amp; Educational Research
L1  - internal-pdf://2654862376/Black 2018.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GO0IQTimes Cited: 0Cited Reference Count: 66Black, Marie E. Therrien, William J.03Sage publications incThousand oaks1538-4756
PY  - 2018
SP  - 243-256
T2  - Remedial and Special Education
TI  - Parent Training Programs for School-Age Children With Autism: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000439610000004
VL  - 39
ER  -
TY  - JOUR
AB  - **Background**
Research suggests that the number of intellectually disabled people with children is increasing. Intellectual disabilities do not inevitably cause parenting difficulties, but it may impact on an individual&#039;s capacity to parent a child effectively. Children of parents with intellectual disabilities may be at increased risk of neglectful care, which could lead to health, developmental and behavioural problems, or increased risk of intellectual disability. Compared with other parents, those with intellectual disabilities are more likely to be involved in care proceedings.

**Objectives**
To assess the effectiveness of parent training interventions for parents with intellectual disabilities designed to support parenting, parent‐child relations, safe parenting or family environments, or to develop parenting skills.

**Search methods**
In July 2017, we searched CENTRAL, Ovid MEDLINE, Embase, CINAHL and six other databases as well as two trials registers. We also searched reference lists of included studies and contacted experts in the field to identify additional ongoing and unpublished studies.

**Selection criteria**
Randomised controlled trials (RCTs) and quasi‐RCTs comparing parent training interventions for parents with intellectual disabilities with treatment as usual or a control group.

**Data collection and analysis**
We used standardised Cochrane methods.

**Main results**
As of July 2017, we identified four trials with 192 participants that met the review inclusion criteria. Participating parents were mostly mothers (seven fathers were included in two studies), and children&#039;s ages ranged from one month to six years and five months.

One study was conducted in Australia, one in Canada, one in the Netherlands, and one in the USA. Each studied a different intervention and considered different outcomes. Three interventions were delivered at home, and one in a community venue (e.g. a church). Interventions varied in duration from seven weeks to 12 months. They included a range of practical childcare skills, home safety and developing parents&#039; ability to respond sensitively to their children. Parents in the comparison groups included in the review received treatment as usual and most of these received the index intervention after the study was complete.

One study was funded by the Ontario Mental Health Foundation and the Ontario Ministry of Community and Social Services Research Grants Program; one by the Alabama Development Disabilities Council; one by the Best Practice Parenting Education Initiative of the Commonwealth Department of Family and Community Services and the New South Wales Aging and Disability Department; and one by ZonMw, The Netherlands Organisation for Health Research and Development.

It was not possible for us to conduct a meta‐analysis. The GRADE quality assessment varied from very low to moderate across the studies.

**Primary outcomes**

No study reported on the &#039;attainment of specific parenting skill targets&#039;.

&#039;Safe home practices&#039; and &#039;understanding of child health&#039;: one study (30 parents, very low‐quality evidence) reported some improvements in parents&#039; knowledge of life‐threatening emergencies, ability to recognise dangers, and identify precautions, in favour of the intervention group. It also found limited, very low‐quality evidence that parent training improved parents&#039; ability to understand child health, implement precautions, use medicines safely, recognise child illness and symptoms, and seek medical advice (i.e. visit the doctor). Another study (22 mothers, very low‐quality evidence) reported improved attainment of skills related to childcare and safety, in favour of the intervention group.

**Secondary outcomes**

&#039;Parent‐child interaction&#039;: one study (40 mothers, very low‐quality evidence) reported improved maternal‐child interaction following parent training at 12 months follow‐up. Another study (83 mothers, 2 fathers, moderate‐quality evidence) reported that inclusion in the intervention group led to a steeper decline in parenting stress related to the child compared to the control group.

&#039;Parents&#039; retention of child&#039;: one study (22 participants; very low‐quality evidence) reported that before joining the programme nine of 11 (82%) families with a previous child had had the child removed from their care by child protection authorities due to maternal maltreatment, compared with only four of 22 (19%) families after participating in the programme (only one of these four mothers had also had a previous child removed).

No study reported data on: &#039;return to independent care of child&#039; or &#039;lifting of child‐related court order&#039;.

**Authors&#039; conclusions**
There is some very low‐quality evidence that some parents, mainly mothers, with intellectual disabilities are able to provide adequate parenting if they are given appropriate training and support to learn the parenting skills they need. However, there are few studies exploring how interventions might work, for whom and in what circumstances. In particular, there have been few studies that include fathers with intellectual disabilities, or that explore the views of parents themselves.

There is a need for larger RCTs of parenting interventions, with longer follow‐up, before conclusions can be drawn about the effectiveness of parent training for this group of parents.
AU  - Coren,
AU  - E.
AU  - Ramsbotham,
AU  - K.
AU  - Gschwandtner,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD007987.pub3
L1  - internal-pdf://2118255164/Coren_et_al-2018-Cochrane_Database_of_Systemat.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Parent training interventions for parents with intellectual disability
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Fetal alcohol spectrum disorder (FASD) is a preventable, lifelong neurodevelopmental disorder caused by prenatal alcohol exposure. FASD negatively impacts individual Indigenous communities around the world. Although many prevention interventions have been developed and implemented, they have not been adequately evaluated. This systematic review updates the evidence for the effectiveness of FASD prevention interventions in Indigenous/Aboriginal populations internationally, and in specific populations in North America and New Zealand, and offers recommendations for future work.

**METHOD:** 
The MEDLINE, Embase, CINAHL Plus, Web of Science, PsycINFO, SocINDEX, and Informit databases were searched from inception to 22/08/2017 for all prevention and intervention papers published in peer-reviewed scientific journals, with results, targeting prenatal alcohol exposure and FASD in Indigenous populations. This review was limited to studies published in English and excluded interventions focusing on the workforce. All steps were completed independently by two reviewers with discrepancies resolved via consensus with the senior author.

**RESULTS:** 
There was significant heterogeneity in the ten included studies. Populations targeted included non-pregnant women of child-bearing age, pregnant women, school children and the general public. Study designs included one randomised controlled trial, five cohort studies with pre-post design, one cross-sectional study with different pre- and post-intervention groups, and four studies collected post-intervention data. Studies assessed changes in knowledge, and/or changes in risk for prenatal alcohol exposure including self-reported alcohol consumption, use of birth control or a combination of both. One study was conducted in Australia and nine in the US. The methodological quality of all studies was rated as &#039;Poor&#039; using the systematic review assessment tools developed by The National Heart, Lung and Blood Institute. Studies were subject to substantial bias due to issues such as high loss to follow-up, lack of control groups and the reliance on self-report measures to assess the main outcome.

**CONCLUSION:** 
Overall, there is little evidence that previous interventions aiming to reduce the risk of prenatal alcohol exposure or FASD in Indigenous populations have been effective. Future intervention studies should address the cultural factors and historical context that are fundamental to successful work with Indigenous populations, and be designed, implemented and evaluated using rigorous methods. This systematic review was registered with PROSPERO, CRD42018086212.
AD  - Symons, Martyn. Telethon Kids Institute, The University of Western Australia, PO Box 855, West Perth, Perth, WA, 6872, Australia. martyn.symons@telethonkids.org.au.Symons, Martyn. National Health and Medical Research Council FASD Research Australia Centre of Research Excellence, Perth, Australia. martyn.symons@telethonkids.org.au.Pedruzzi, Rebecca Anne. Telethon Kids Institute, The University of Western Australia, PO Box 855, West Perth, Perth, WA, 6872, Australia.Bruce, Kaashifah. Telethon Kids Institute, The University of Western Australia, PO Box 855, West Perth, Perth, WA, 6872, Australia.Milne, Elizabeth. Telethon Kids Institute, The University of Western Australia, PO Box 855, West Perth, Perth, WA, 6872, Australia.
AN  - 30390661
AU  - Symons,
AU  - M.
AU  - Pedruzzi,
AU  - R.
AU  - A.
AU  - Bruce,
AU  - K.
AU  - Milne,
AU  - E.
DA  - Nov 03
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s12889-018-6139-5
DP  - Ovid Technologies
J2  - BMC Public Health
KW  - *Alcohol Drinking/pc [Prevention &amp; Control]
KW  - Australia
KW  - Female
KW  - *Fetal Alcohol Spectrum Disorders/pc [Prevention &amp; Control]
KW  - Humans
KW  - *Population Groups
KW  - Pregnancy
KW  - *Prenatal Exposure Delayed Effects/pc [Prevention &amp; Control]
KW  - Randomized Controlled Trials as Topic
KW  - United States
L1  - internal-pdf://2598604088/Symons-2018-A systematic review of prevention.pdf
LA  - English
M3  - Review
N1  - Symons, MartynPedruzzi, Rebecca AnneBruce, KaashifahMilne, Elizabeth
PY  - 2018
SP  - 1227
T2  - BMC Public Health
TI  - A systematic review of prevention interventions to reduce prenatal alcohol exposure and fetal alcohol spectrum disorder in indigenous communities
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=30390661
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30390661&amp;id=doi:10.1186%2Fs12889-018-6139-5&amp;issn=1471-2458&amp;isbn=&amp;volume=18&amp;issue=1&amp;spage=1227&amp;pages=1227&amp;date=2018&amp;title=BMC+Public+Health&amp;atitle=A+systematic+review+of+prevention+interventions+to+reduce+prenatal+alcohol+exposure+and+fetal+alcohol+spectrum+disorder+in+indigenous+communities.&amp;aulast=Symons&amp;pid=%3Cauthor%3ESymons+M%3C%2Fauthor%3E%3CAN%3E30390661%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215602/pdf/12889_2018_Article_6139.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - A number of studies of parent-mediated interventions in autism spectrum disorder have been published in the last 15 years. 

We reviewed 19 randomized clinical trials of parent-mediated interventions for children with autism spectrum disorder between the ages of 1 and 6 years and conducted a meta-analysis on their efficacy. Meta-analysis outcomes were autism spectrum disorder symptom severity, socialization, communication-language, and cognition. 

Quality of evidence was rated as moderate for autism spectrum disorder symptom severity, communication-language, and cognition, and very low for socialization. Weighted Hedges&#039; g varied from 0.18 (communication-language) to 0.27 (socialization) and averaged 0.23 across domains. We also examined the relationship between outcome and dose of parent training, type of control group, and type of informant (parent and clinician). 

Outcomes were not significantly different based on dose of treatment. Comparing parent training to treatment-as-usual did not result in significantly different treatment effects than when parent training was compared to an active comparison group. 

Based on parent report only, treatment effects were significant for communication-language and non-significant for socialization, yet the opposite was found based on clinician-rated tools. 

This meta-analysis suggests that while most outcome domains of parent-delivered intervention are associated with small effects, the quality of research is improving. 

Copyright &copy; 2016, &copy; The Author(s) 2016.
AN  - 621062793
AU  - Nevill,
AU  - R.
AU  - E.
AU  - Lecavalier,
AU  - L.
AU  - Stratis,
AU  - E.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1362361316677838
L1  - internal-pdf://2885676745/Nevill-2018-Meta-analysis of parent-mediated i.pdf
PY  - 2018
SP  - 84-98
T2  - Autism
TI  - Meta-analysis of parent-mediated interventions for young children with autism spectrum disorder
UR  - http://www.sageltd.co.uk/journals/details/j0192.html
UR  - http://journals.sagepub.com/doi/pdf/10.1177/1362361316677838
VL  - 22
ER  -
TY  - JOUR
AB  - **Objective **
This meta-analysis evaluated the efficacy of behavioral classroom programs on symptoms of Attention-deficit Hyperactivity Disorder or Oppositional Defiant and/or Conduct Disorder in primary school children. 

**Method **
Online database searches (in PubMed, Embase, Psycinfo, and Eric) yielded nineteen randomized controlled trials (N = 18,094), comparing behavioral classroom programs (including multimodal programs involving a classroom program) to no treatment/treatment as usual. Random-effects meta-analyses were conducted for teacher-rated and classroom-observed disruptive classroom behavior and for classroom-observed on-task behavior. Post-hoc analyses investigated whether effects depended on type and severity of problem behavior. Meta-regressions studied the moderating effects of age, gender, and intervention duration. 

**Results **
Small positive effects were found on teacher-rated disruptive behavior (d = -0.20) and classroom- observed on-task behavior (d = 0.39). Program effects on teacher-rated disruptive behavior were unrelated to age, gender, type and severity, but negatively associated with intervention duration (R&lt;sup&gt;2&lt;/sup&gt; = 0.43).

**Conclusion **
Behavioral classroom programs have small beneficial effects on disruptive behavior and ontask behavior. Results advocate universal programs for entire classrooms to prevent and reduce disruptive classroom behavior. 

Copyright &copy; 2018 Veenman et al. 
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AD  - (Veenman, Luman, Oosterlaan) Clinical Neuropsychology Section, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
AN  - 624279527
AU  - Veenman,
AU  - B.
AU  - Luman,
AU  - M.
AU  - Oosterlaan,
AU  - J.
DA  - October
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0201779
DP  - Ovid Technologies
KW  - article
KW  - attention deficit disorder
KW  - child
KW  - comparative effectiveness
KW  - conduct disorder
KW  - drug efficacy
KW  - Embase
KW  - female
KW  - gender
KW  - human
KW  - male
KW  - Medline
KW  - meta analysis
KW  - post hoc analysis
KW  - primary school
KW  - problem behavior
KW  - PsycINFO
KW  - randomized controlled trial (topic)
KW  - systematic review
KW  - teacher
L1  - internal-pdf://2830874060/Veenman-2018-Efficacy of behavioral classroom.pdf
LA  - English
PY  - 2018
T2  - PLoS ONE
TI  - Efficacy of behavioral classroom programs in primary school. A meta-analysis focusing on randomized controlled trials
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0201779&amp;type=printable
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=624279527
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:30303966&amp;id=doi:10.1371%2Fjournal.pone.0201779&amp;issn=1932-6203&amp;isbn=&amp;volume=13&amp;issue=10&amp;spage=e0201779&amp;pages=&amp;date=2018&amp;title=PLoS+ONE&amp;atitle=Efficacy+of+behavioral+classroom+programs+in+primary+school.+A+meta-analysis+focusing+on+randomized+controlled+trials&amp;aulast=Veenman&amp;pid=%3Cauthor%3EVeenman+B.%3C%2Fauthor%3E%3CAN%3E624279527%3C%2FAN%3E%3CDT%3EArticle%3C%2FDT%3E
VL  - 13 (10) (no pagination)
ER  -
TY  - JOUR
AB  - Anxiety-focused cognitive-behavioral therapy (CBT) effectively reduces anxiety in children and adolescents. An important remaining question is to what extent anxiety-focused CBT also affects broader outcome domains. 

Additionally, it remains unclear whether parental involvement in treatment may have impact on domains other than anxiety. A meta-analysis (n&lt;sub&gt;studies&lt;/sub&gt; = 42, n&lt;sub&gt;participants&lt;/sub&gt; = 3239) of the effects of CBT and the moderating role of parental involvement was conducted on the following major secondary outcomes: depressive symptoms, externalizing behaviors, general functioning, and social competence. 

Randomized controlled trials were included when having a waitlist or active control condition, a youth sample (aged&lt;19) with a primary anxiety disorder diagnosis receiving anxiety-focused CBT and reported secondary outcomes. Controlled effect sizes (Cohen&#039;s d) were calculated employing random effect models. CBT had a large effect on general functioning (-1.25[-1.59;0.90], n&lt;sub&gt;studies&lt;/sub&gt; = 17), a small to moderate effect on depressive symptoms (-0.31[-0.41;-0.22], n&lt;sub&gt;studies&lt;/sub&gt; = 31) and a small effect on externalizing behaviors (-0.23[-0.38;-0.09], n&lt;sub&gt;studies&lt;/sub&gt; = 12) from pre-to post-treatment.

Effects remained or even further improved at follow-up. Social competence only improved at follow-up (n&lt;sub&gt;studies&lt;/sub&gt; = 6). Concluding, anxiety-focused CBT has a positive effect on broader outcome domains than just anxiety. Higher parental involvement seemed to have beneficial effects at follow-up, with improvements in general functioning and comorbid symptoms.
AN  - 30447493
AU  - Kreuze,
AU  - L.
AU  - J.
AU  - Pijnenborg,
AU  - G.
AU  - H.
AU  - M.
AU  - de
AU  - Jonge,
AU  - Y.
AU  - B.
AU  - Nauta,
AU  - M.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.janxdis.2018.10.005
L1  - internal-pdf://3646360125/Kreuze-2018-Cognitive-behavior therapy for chi.pdf
PY  - 2018
SP  - 43-57
T2  - Journal of Anxiety Disorders
TI  - Cognitive-behavior therapy for children and adolescents with anxiety disorders: A meta-analysis of secondary outcomes
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30447493
UR  - https://ac.els-cdn.com/S0887618518300574/1-s2.0-S0887618518300574-main.pdf?_tid=d322a9ef-6d1d-4991-ab49-832e4b86e3ba&amp;acdnat=1547554246_1ad280026002d485b2876330833016b2
VL  - 60
ER  -
TY  - JOUR
AB  - **Objective: **
To determine the trajectory and magnitude of antidepressant response as well as the effect of antidepressant class and dose on symptomatic improvement in pediatric anxiety disorders. 

**Method: **
Weekly symptom severity data were extracted from randomized, parallel group, placebo-controlled trials of selective serotonin reuptake inhibitors (SSRIs) and selective serotonin-norepinephrine reuptake inhibitors (SNRIs) in pediatric anxiety disorders. Treatment response was modeled for the standardized change in continuous measures of anxiety using Bayesian updating. Posterior distributions for each study served as informative conjugate prior to distributions update subsequent study posteriors. Change in symptom severity was evaluated as a function of time, class and, for SSRIs, standardized dose. 

**Results: **
Data from 9 trials (SSRIs: n = 5; SNRIs, n = 4) evaluating 7 medications in 1,673 youth were included. In the logarithmic model of treatment response, statistically, but not clinically, significant treatment effects emerged within 2 weeks of beginning treatment (standardized medication-placebo difference = -0.054, credible interval [CI] = -0.076 to -0.032, p = .005, approximate Cohen&#039;s d &lt;= 0.2) and by week 6, clinically significant differences emerged (standardized medication-placebo difference = -0.120, CI = -0.142 to -0.097, p = .001, approximate Cohen&#039;s d = 0.44). Compared to SNRIs, SSRIs resulted in significantly greater improvement by the second week of treatment (p = .0268), and this advantage remained statistically significant through week 12 (all p values &lt; .03). Improvement occurred earlier with high-dose SSRI treatment (week 2, p = .002) compared to low-dose treatment (week 10, p = .025), but SSRI dose did not have an impact on overall response trajectory (p &gt; .18 for weeks 1-12).

**Conclusions: **
In pediatric patients with generalized, separation, and/or social anxiety disorders, antidepressant-related improvement occurred early in the course of treatment, and SSRIs were associated with more rapid and greater improvement compared to SNRIs. 

(PsycINFO Database Record (c) 2018 APA, all rights reserved)
AD  - Strawn, Jeffrey R.: strawnjr@uc.eduStrawn, Jeffrey R.: University of Cincinnati, Department of Psychiatry, Box 670559, Cincinnati, OH, US, 45267-0559, strawnjr@uc.eduStrawn, Jeffrey R.: University of Cincinnati, College of Medicine, Cincinnati, OH, USMills, Jeffrey A.: Carl H. Lindner College of Business, University of Cincinnati, Cincinnati, OH, USSauley, Beau A.: Carl H. Lindner College of Business, University of Cincinnati, Cincinnati, OH, USWelge, Jeffrey A.: University of Cincinnati, College of Medicine, Cincinnati, OH, US
AN  - 2018-13722-008
AU  - Strawn,
AU  - Jeffrey
AU  - R.
AU  - Mills,
AU  - Jeffrey
AU  - A.
AU  - Sauley,
AU  - Beau
AU  - A.
AU  - Welge,
AU  - Jeffrey
AU  - A.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2018.01.015
DP  - Ovid Technologies
KW  - selective serotonin reuptake inhibitor (SSRI, SRI), selective serotonin-norepinephrine reuptake inhibitor (SSNRI, SNRI), separation anxiety disorder (SAD), social phobia (SoP), generalized anxiety disorder (GAD)
KW  - *Antidepressant Drugs
KW  - *Anxiety Disorders
KW  - *Pediatrics
KW  - *Treatment
KW  - Clinical Psychopharmacology [3340]
KW  - Human Male Female Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://4025950112/Strawn-2018-The impact of antidepressant dose.pdf
LA  - English
M3  - Empirical Study; Meta Analysis; Quantitative Study
PY  - 2018
SP  - 235-244
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - The impact of antidepressant dose and class on treatment response in pediatric anxiety disorders: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2018-13722-008
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jaac.2018.01.015&amp;issn=0890-8567&amp;isbn=&amp;volume=57&amp;issue=4&amp;spage=235&amp;pages=235-244&amp;date=2018&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=The+impact+of+antidepressant+dose+and+class+on+treatment+response+in+pediatric+anxiety+disorders%3A+A+meta-analysis.&amp;aulast=Strawn&amp;pid=%3Cauthor%3EStrawn%2C+Jeffrey+R%3C%2Fauthor%3E%3CAN%3E2018-13722-008%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S0890856718300534/1-s2.0-S0890856718300534-main.pdf?_tid=22b8e66a-1f21-48c6-a73b-91d98cf739d5&amp;acdnat=1533218581_b1d83aced0b2fe0e36fdc4b69863ccc4
VL  - 57
ER  -
TY  - JOUR
AB  - **Background: **
The aim of the study was a systematic review of studies evaluating psychotherapeutic treatment approaches in anorexia nervosa and to compare their efficacy. Weight gain was chosen as the primary outcome criterion. We also aimed to compare treatment effects according to service level (inpatient vs. outpatient) and age group (adolescents vs. adults). 

**Methods:**
The data bases PubMed, Cochrane Library, Web of Science, Cinahl, and PsychInfo were used for a systematic literature search (until Feb 2017). Search terms were adapted for data base, combining versions of the search terms anorexia, treat*/therap* and controlled trial. Studies were selected using pre-defined in- and exclusion criteria. Data were extracted by two independent coders using piloted forms. Network-meta-analyses were conducted on all RCTs. For a comparison of service levels and age groups, standard mean change (SMC) statistics were used and naturalistic, non-randomized studies included. 

**Results: **
Eighteen RCTs (trials on adults: 622 participants; trials on adolescents: 625 participants) were included in the network meta-analysis. SMC analyses were conducted with 38 studies (1,164 participants). While family-based approaches dominate interventions for adolescents, individual psychotherapy dominates in adults. There was no superiority of a specific approach. Weight gains were more rapid in adolescents and inpatient treatment. 

**Conclusions: **
Several specialized psychotherapeutic interventions have been developed and can be recommended for AN. However, adult and adolescent patients should be distinguished, as groups differ in terms of treatment approaches considered suitable as well as treatment response. 

Future trials should replicate previous findings and be multi-center trials with large sample sizes to allow for subgroup analyses. Patient assessment should include variables that can be considered relevant moderators of treatment outcome. It is desirable to explore adaptive treatment strategies for subgroups of patients with AN. Identifying and addressing maintaining factors in AN remains a major challenge. 

Copyright &copy; 2018 Zeeck, Herpertz-Dahlmann, Friederich, Brockmeyer, Resmark, Hagenah, Ehrlich, Cuntz, Zipfel and Hartmann.
AD  - (Zeeck, Hartmann) Department of Psychosomatic Medicine and Psychotherapy, Faculty of Medicine, Medical Center-University of Freiburg, University of Freiburg, Freiburg, Germany (Herpertz-Dahlmann, Hagenah, Zipfel) Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of the RWTH Aachen, Aachen, Germany (Friederich, Brockmeyer) Department of Psychosomatic Medicine and Psychotherapy, Medical Faculty, Heinrich Heine University, Dusseldorf, Germany (Resmark) Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tuebingen, Tuebingen, Germany (Ehrlich) Division of Psychological and Social Medicine and Developmental Neurosciences, Department of Child and Adolescent Psychiatry, Faculty of Medicine, Technische Universitaet Dresden, Dresden, Germany (Cuntz) Schon Klinik Roseneck, Prien am Chiemsee, GermanyA. Zeeck, Department of Psychosomatic Medicine and Psychotherapy, Faculty of Medicine, Medical Center-University of Freiburg, University of Freiburg, Freiburg, Germany. E-mail: almut.zeeck@uniklinik-freiburg.de
AN  - 622065757
AU  - Zeeck,
AU  - A.
AU  - Herpertz-Dahlmann,
AU  - B.
AU  - Friederich,
AU  - H.
AU  - C.
AU  - Brockmeyer,
AU  - T.
AU  - Resmark,
AU  - G.
AU  - Hagenah,
AU  - U.
AU  - Ehrlich,
AU  - S.
AU  - Cuntz,
AU  - U.
AU  - Zipfel,
AU  - S.
AU  - Hartmann,
AU  - A.
DA  - 01 May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3389/fpsyt.2018.00158
DP  - Ovid Technologies
KW  - Anorexia nervosa
KW  - Eating disorders
KW  - Meta-analysis
KW  - Psychotherapy
KW  - Systematic review
KW  - age distribution
KW  - anorexia nervosa/th [Therapy]
KW  - body weight gain
KW  - cognitive behavioral therapy
KW  - cognitive remediation therapy
KW  - counseling
KW  - data analysis
KW  - diet therapy
KW  - family therapy
KW  - hospital patient
KW  - human
KW  - human relation
KW  - meta analysis
KW  - network meta-analysis
KW  - outpatient
KW  - psychoanalysis
KW  - psychodynamic psychotherapy
KW  - randomized controlled trial (topic)
KW  - review
KW  - statistical analysis
KW  - treatment outcome
L1  - internal-pdf://0023672342/Zeeck-2018-Psychotherapeutic treatment for ano.pdf
LA  - English
M3  - Review
PY  - 2018
T2  - Frontiers in Psychiatry
TI  - Psychotherapeutic treatment for anorexia nervosa: A systematic review and network meta-analysis
UR  - https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00158/full
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=622065757
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.3389%2Ffpsyt.2018.00158&amp;issn=1664-0640&amp;isbn=&amp;volume=9&amp;issue=MAY&amp;spage=158&amp;pages=&amp;date=2018&amp;title=Frontiers+in+Psychiatry&amp;atitle=Psychotherapeutic+treatment+for+anorexia+nervosa%3A+A+systematic+review+and+network+meta-analysis&amp;aulast=Zeeck&amp;pid=%3Cauthor%3EZeeck+A.%3C%2Fauthor%3E%3CAN%3E622065757%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://fjfsdata01prod.blob.core.windows.net/articles/files/341079/pubmed-zip/.versions/1/.package-entries/fpsyt-09-00158/fpsyt-09-00158.pdf?sv=2015-12-11&amp;sr=b&amp;sig=pXKJf1mwi0GsNZYiJC6skt3zpJZTLZiTty%2FGOnH2Dg0%3D&amp;se=2018-08-02T14%3A01%3A26Z&amp;sp=r&amp;rscd=attachment%3B%20filename%2A%3DUTF-8%27%27fpsyt-09-00158.pdf
VL  - 9 (MAY) (no pagination)
ER  -
TY  - JOUR
AB  - **Background**
Depression is common in the postnatal period and can lead to adverse effects on the infant and wider family, in addition to the morbidity for the mother. It is not clear whether antidepressants are effective for the prevention of postnatal depression and little is known about possible adverse effects for the mother and infant, particularly during breastfeeding. This is an update of a Cochrane Review last published in 2005.

**Objectives**
To assess the effectiveness of antidepressant medication for the prevention of postnatal depression, in comparison with any other treatment, placebo or standard care.

**Search methods**
We searched the Cochrane Common Mental Disorders Controlled Trials Register (CCMDCTR ‒ both Studies and References), CENTRAL (Wiley), MEDLINE (OVID), Embase (OVID), PsycINFO (OVID), on 13 February 2018. We also searched the World Health Organization (WHO) trials portal (ICTRP) and ClinicalTrials.gov on 13 February 2018 to identify any additional unpublished or ongoing studies.

**Selection criteria**
Randomised controlled trials (RCTs) of initiation of antidepressants (alone or in combination with another treatment), compared with any other treatment, placebo or standard care for the prevention of postnatal depression among women who were either pregnant or had given birth in the previous six weeks and were not currently depressed at baseline.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane. We requested missing information from investigators wherever possible and sought data to allow intention‐to‐treat analyses.

**Main results**
Two trials including a total of 81 participants fulfilled the inclusion criteria for this review. All participants in both studies had a history of postnatal depression and were not taking antidepressant medication at baseline. Both trials were conducted by the same research group. Risk of bias was low or unclear in most domains for both studies. We were unable to perform a meta‐analysis due to the small number of studies.

One study compared nortriptyline with placebo and did not find any evidence that nortriptyline was effective in preventing postnatal depression. In this study, 23% (6/26) of women who took nortriptyline and 24% (6/25) of women who took placebo experienced postnatal depression (RR 0.96, 95% CI 0.36 to 2.59, very low quality evidence) in the first 17 weeks postpartum. One woman taking nortriptyline developed mania; and one side effect, constipation, was more common among women taking nortriptyline than those taking placebo.

The second study compared sertraline with placebo. In this study, 7% (1/14) of women who took sertraline developed postnatal depression in the first 17 weeks postpartum compared with 50% (4/8) of women who took placebo. It is uncertain whether sertraline reduces the risk of postnatal depression (RR 0.14, 95% CI 0.02 to 1.07, very low quality evidence). One woman taking sertraline had a hypomanic episode. Two side effects (dizziness and drowsiness) were more common among women taking sertraline than women taking placebo.

Conclusions are limited by the small number of studies, small sample sizes and incomplete outcome data due to study drop‐out which may have led to bias in the results. We have assessed the certainty of the evidence as very low, based on the GRADE system. No data were available on secondary outcomes of interest including child development, the mother‒infant relationship, breastfeeding, maternal daily functioning, family relationships or maternal satisfaction.

**Authors&#039; conclusions**
Due to the limitations of the current evidence base, such as the low statistical power of the included studies, it is not possible to draw any clear conclusions about the effectiveness of antidepressants for the prevention of postnatal depression. It is striking that no new eligible trials have been completed in the period of over a decade since the last published version of this review. Larger trials are needed which include comparisons of antidepressant drugs with other prophylactic treatments (e.g. psychological interventions), and examine adverse effects for the fetus or infant. Future reviews in this area may benefit from broadening their focus to examine the effectiveness of antidepressants for the prevention of perinatal (i.e. antenatal or postnatal) depression, which could include studies comparing antidepressant discontinuation with continuation for the prevention of relapse of depression during pregnancy and the postnatal period.
AU  - Molyneaux,
AU  - E.
AU  - Telesia,
AU  - L.
AU  - A.
AU  - Henshaw,
AU  - C.
AU  - Boath,
AU  - E.
AU  - Bradley,
AU  - E.
AU  - Howard,
AU  - L.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD004363.pub3
L1  - internal-pdf://3856401834/Molyneaux_et_al-2018-Cochrane_Database_of_Syst.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Update: Antidepressants for preventing postnatal depression
ER  -
TY  - JOUR
AB  - **Purpose: **
Attention-deficit/hyperactivity disorder (ADHD) medications are used by increasing numbers of reproductive-age women. The safety of these medications during pregnancy has not been well described. 

**Method(s): **
A systematic review and meta-analysis was performed to evaluate the adverse maternal and neonatal outcomes associated with exposure to ADHD medication during pregnancy. The PubMed and Embase databases were searched to identify potential studies for inclusion. 

**Result(s): **
Eight cohort studies that estimated adverse maternal or neonatal outcomes associated with exposure to ADHD medication during pregnancy were included. Exposure to ADHD medication was associated with an increased risk of neonatal intensive care unit (NICU) admission compared with no exposure at any time (risk ratio (RR) 1.88; 95% confidence interval (CI), 1.7-2.08) and compared with women with exposure either before or after pregnancy (RR 1.38; 95% CI, 1.23-1.54; P &lt; 0.001). Exposure to methylphenidate (MPH) was marginally associated with an increased risk for cardiac malformation (RR 1.27; 95% CI, 0.99-1.63; P = 0.065) compared with no exposure. However, exposure to ADHD medication was not associated with an increased risk for other adverse maternal or neonatal outcomes. This analysis was limited by the small number of studies included and the limited adjustments for the possible confounders in the studies. 

**Conclusion(s): **
Exposure to ADHD medication during pregnancy does not appear to be associated with adverse maternal or neonatal outcomes. Given the few studies included, further larger, prospective studies that control for important confounders are needed to verify our findings. 

Copyright &copy; 2018 John Wiley &amp; Sons, Ltd.
AN  - 625655586
AU  - Jiang,
AU  - H.
AU  - Y.
AU  - Zhang,
AU  - X.
AU  - Jiang,
AU  - C.
AU  - M.
AU  - Fu,
AU  - H.
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/pds.4716
L1  - internal-pdf://2442112651/Jiang-2018-Maternal and neonatal outcomes afte.pdf
PY  - 2018
TI  - Maternal and neonatal outcomes after exposure to ADHD medication during pregnancy: A systematic review and meta-analysis
UR  - http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1099-1557
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1002/pds.4716
ER  -
TY  - JOUR
AB  - Lithium and antipsychotics are often prescribed to treat bipolar disorder or psychotic disorders in women of childbearing age. Little is known about the consequences of these medications during pregnancy for the developing child. The objective of this article is to systematically review findings from preclinical and clinical studies that have examined the neurodevelopmental consequences of intrauterine exposure to lithium and antipsychotics. 

A systematic search was performed in Embase, Medline, Web of Science, PsychINFO, Cochrane, and Google Scholar. Clinical and experimental studies were selected if they investigated neurodevelopment of offspring exposed to lithium or antipsychotics during gestation. Quality of clinical and preclinical studies was assessed by the Newcastle-Ottawa Scale and the SYRCLE&#039;s risk of Bias tool, respectively. In total, 73 studies were selected for qualitative synthesis and three studies were selected for quantitative synthesis. 

Of preclinical studies, 93% found one or more adverse effects of prenatal exposure to antipsychotics or lithium on neurodevelopment or behaviour. Only three clinical cohort studies have investigated the consequences of lithium exposure, all of which reported normal development. In 66% of clinical studies regarding antipsychotic exposure, a transient delay in neurodevelopment was observed. The relative risk for neuromotor deficits after in utero exposure to antipsychotics was estimated to be 1.63 (95% CI 1.22-2.19; I-2=0%). 

Preclinical studies suggest long-term adverse neurodevelopmental consequences of intrauterine exposure to either lithium or antipsychotics. However, there is a lack of high-quality clinical studies. Interpretation is difficult, since most studies have compared exposed children with their peers from the unaffected population, which did not allow correction for potential influences regarding genetic predisposition or parental psychiatric illness.
AD  - [Poels, Eline M. P.; Schrijver, Lisanne; Kamperman, Astrid M.; Hoogendijk, Witte J. G.; Kushner, Steven A.; Roza, Sabine J.] Erasmus Univ, Dept Psychiat, Med Ctr, S Gravendijkwal 230, NL-3015 CE Rotterdam, Netherlands. [Hillegers, Manon H. J.] Erasmus Univ, Med Ctr, Dept Child &amp; Adolescent Psychiat, Rotterdam, Netherlands.Poels, EMP (reprint author), Erasmus Univ, Dept Psychiat, Med Ctr, S Gravendijkwal 230, NL-3015 CE Rotterdam, Netherlands.e.poels@erasmusmc.nl
AN  - WOS:000444037200011
AU  - Poels,
AU  - E.
AU  - M.
AU  - P.
AU  - Schrijver,
AU  - L.
AU  - Kamperman,
AU  - A.
AU  - M.
AU  - Hillegers,
AU  - M.
AU  - H.
AU  - J.
AU  - Hoogendijk,
AU  - W.
AU  - J.
AU  - G.
AU  - Kushner,
AU  - S.
AU  - A.
AU  - Roza,
AU  - S.
AU  - J.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-018-1177-1
J2  - Eur. Child Adolesc. Psych.
KW  - Lithium
KW  - Antipsychotics
KW  - Pregnancy
KW  - Neurodevelopment
KW  - Intrauterine
KW  - exposure
KW  - prenatal haloperidol exposure
KW  - bipolar disorder
KW  - in-utero
KW  - apoptotic
KW  - neurodegeneration
KW  - psychotropic medication
KW  - postnatal-development
KW  - tranquilizing drugs
KW  - mental-illness
KW  - matter volumes
KW  - follow-up
KW  - Psychology
KW  - Pediatrics
KW  - Psychiatry
L1  - internal-pdf://0908403216/Poels-2018-Long-term neurodevelopmental conseq.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GS9KOTimes Cited: 0Cited Reference Count: 121Poels, Eline M. P. Schrijver, Lisanne Kamperman, Astrid M. Hillegers, Manon H. J. Hoogendijk, Witte J. G. Kushner, Steven A. Roza, Sabine J.Kamperman, Astrid/J-8046-2015Kamperman, Astrid/0000-0003-4455-649201SpringerNew york1435-165x
PY  - 2018
SP  - 1209-1230
T2  - European Child &amp; Adolescent Psychiatry
TI  - Long-term neurodevelopmental consequences of intrauterine exposure to lithium and antipsychotics: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000444037200011
UR  - https://link.springer.com/content/pdf/10.1007%2Fs00787-018-1177-1.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - **Background: **
Drug-induced QT prolongation is associated with higher risk of cardiac arrhythmias and cardiovascular mortality. We investigated the effects of atypical antipsychotic drugs on QT interval in children and adults with mental disorders.

**Methods: **
We conducted random-effects direct frequentist meta-analyses of aggregate data from randomized controlled trials (RCT) and appraised the quality of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. Our search in PubMed, EMBASE, the Cochrane Library, clinicaltrials.gov, and PharmaPendium up to October 2017 identified studies that examined aripiprazole, quetiapine, risperidone, olanzapine, ziprasidone and brexpiprazole.

**Results: **
Low quality evidence suggests that aripiprazole (four meta-analyses and twelve RCTs), brexpiprazole (one systematic review and four RCTs) or olanzapine (five meta-analyses and twenty RCTs) do not increase QT interval. Low quality evidence suggests that ziprasidone (five meta-analyses and 11 RCTs) increases QT interval and the rates of QT prolongation while risperidone (four meta-analyses, 70 RCTs) and quetiapine (two meta-analyses and seven RCTs) are associated with QT prolongation and greater odds of torsades de pointes ventricular tachycardia especially in cases of drug overdose.

**Conclusions: **
The main conclusion of our study is that in people with mental disorders and under treatment with atypical antipsychotic drugs, in order to avoid QT prolongation and reduce the risk of ventricular tachycardia clinicians may recommend aripiprazole, brexpiprazole or olanzapine in licensed doses. Long-term comparative safety needs to be established.
AD  - Aronow, Wilbert S. Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.Shamliyan, Tatyana A. Quality Assurance, Evidence-Based Medicine Center, Elsevier, Philadelphia, PA, USA.
AN  - 29862236
AU  - Aronow,
AU  - W.
AU  - S.
AU  - Shamliyan,
AU  - T.
AU  - A.
DA  - Apr
DB  - Rekoding IN SUM_lme.enl
DO  - /10.21037/atm.2018.03.17
DP  - Ovid Technologies
J2  - Ann
L1  - internal-pdf://1333045398/Aronow-2018-Effects of atypical antipsychotic.pdf
LA  - English
N1  - Aronow, Wilbert SShamliyan, Tatyana A
PY  - 2018
SP  - 147
T2  - Annals of Translational Medicine
TI  - Effects of atypical antipsychotic drugs on QT interval in patients with mental disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29862236
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29862236&amp;id=doi:10.21037%2Fatm.2018.03.17&amp;issn=2305-5839&amp;isbn=&amp;volume=6&amp;issue=8&amp;spage=147&amp;pages=147&amp;date=2018&amp;title=Annals+of+Translational+Medicine&amp;atitle=Effects+of+atypical+antipsychotic+drugs+on+QT+interval+in+patients+with+mental+disorders.&amp;aulast=Aronow&amp;pid=%3Cauthor%3EAronow+WS%3C%2Fauthor%3E%3CAN%3E29862236%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952011/pdf/atm-06-08-147.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **Background: **
Recent randomized controlled trials indicated that aripiprazole was the effective treatment for children and adolescents with autism spectrum disorder (ASD). 

**Objective: **
This study systematically reviewed the efficacy, acceptability and tolerability of aripiprazole in treatment of ASD children and adolescents. 

**Data sources:**
Electronic search of databases including, Scopus, PubMed, CINAHL and Cochrane Controlled Trials Register was performed in July 2017. 

**Methods: **
The full-text versions of included trials were meticulously evaluated and extracted. The main efficacious outcomes consisted of pooled mean change scores of the standardized rating scales for ASD and the pooled response rate. 

**Results:**
A total of 408 randomized patients from eligible trials were included for synthesizing in this meta-analysis. The pooled mean change scores in aripiprazole-treated group for the Aberrant Behavior Checklist (ABC)-Irritability, ABC-Hyperactivity/noncompliance, ABC-Inappropriate speech and ABC-Stereotypic behavior were significantly greater than those of the placebo-treated group. Unfortunately, the significant difference between two groups was not found for ABC-Lethargy/social withdrawal. The overall pooled response rate of the aripiprazole-treated group was significantly higher than that of the placebo-treated group. The pooled overall discontinuation rate in aripiprazole-treated group was significantly better than that of placebo-treated group. The pooled discontinuation rates due to adverse events in aripiprazole-treated group significantly differed from the placebo-treated group (RR [95% CI] of 1.43 [0.65, 3.18], I-2=0%). 

**Limitation: **
A small number of studies were gathered in this review. 

**Conclusion: **
Aripiprazole has efficacy in the treatment of behavioral disturbances, including irritability, hyperactivity/noncompliance, inappropriate speech and stereotypic behavior found in ASD children and adolescents; however, it could not improve the lethargy/social withdrawal in such patients. The present evidence also indicates that it is safe, acceptable and tolerable in such treatment. As a small sample size, further well-defined and large sample size studies should be conducted to warrant those findings.
AD  - [Maneeton, Narong; Maneeton, Benchalak; Suttajit, Sirijit; Likhitsathian, Surinporn; Srisurapanont, Manit] Chiang Mai Univ, Dept Psychiat, Fac Med, 110 Intawaroros Rd, Chiang Mai 50200, Thailand. [Putthisri, Suwannee] Mahidol Univ, Ramathibodi Hosp, Dept Psychiat, Fac Med, Bangkok, Thailand.Maneeton, N (reprint author), Chiang Mai Univ, Dept Psychiat, Fac Med, 110 Intawaroros Rd, Chiang Mai 50200, Thailand.narong.m@cmu.ac.th
AN  - WOS:000450297600002
AU  - Maneeton,
AU  - N.
AU  - Maneeton,
AU  - B.
AU  - Putthisri,
AU  - S.
AU  - Suttajit,
AU  - S.
AU  - Likhitsathian,
AU  - S.
AU  - Srisurapanont,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2147/ndt.S174622
J2  - Neuropsychiatr. Dis. Treat.
KW  - Aberrant Behavior Checklist
KW  - ABC
KW  - Children&#039;s Yale Brown Obsessive
KW  - Compulsive Scale
KW  - CY-BOCS
KW  - efficacy
KW  - acceptability
KW  - tolerability
KW  - pervasive developmental disorders
KW  - aberrant behavior checklist
KW  - double-blind
KW  - risperidone
KW  - efficacy
KW  - irritability
KW  - haloperidol
KW  - safety
KW  - symptoms
KW  - antipsychotics
KW  - Neurosciences &amp; Neurology
KW  - Psychiatry
L1  - internal-pdf://0554141767/Maneeton-2018-Aripiprazole in acute treatment.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: HA5GKTimes Cited: 0Cited Reference Count: 35Maneeton, Narong Maneeton, Benchalak Putthisri, Suwannee Suttajit, Sirijit Likhitsathian, Surinporn Srisurapanont, ManitChiang Mai University, ThailandThis meta-analysis received partially financial support from Chiang Mai University, Thailand. We also thank volunteers who carried out the work in the schools. NM and BM are joint first authors.0Dove medical press ltdAlbany
PY  - 2018
SP  - 3063-3072
T2  - Neuropsychiatric Disease and Treatment
TI  - Aripiprazole in acute treatment of children and adolescents with autism spectrum disorder: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000450297600002
UR  - https://www.dovepress.com/getfile.php?fileID=46107
VL  - 14
ER  -
TY  - JOUR
AB  - **Purpose: **
This review evaluates the evidence of the effects of multidimensional family therapy (MDFT) on drug use reduction in young people for the treatment of nonopioid drug use. 

**Method:** 
We followed Campbell Collaboration guidelines to conduct a systematic review of randomized and nonrandomized trials. Meta-analytic methods were used to quantitatively synthesize study results. 

**Results: **
The search yielded five studies that met inclusion criteria. MDFT was found to be more effective than other treatments on drug abuse problem severity and drug use frequency in the short run but not in the long run and demonstrated positive effects on treatment retention compared to control conditions. 

**Discussion: **
While additional research is needed, the review offers support for MDFT as a treatment to young nonopioid drug abusers. The number of studies included in this review was limited, however, and this should be considered when interpreting the results.
AN  - WOS:000417860300007
AU  - Filges,
AU  - T.
AU  - Andersen,
AU  - D.
AU  - Jorgensen,
AU  - A.
AU  - M.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1049731515608241
L1  - internal-pdf://3838680303/Filges-2018-Effects of Multidimensional Family.pdf
PY  - 2018
SP  - 68-83
T2  - Research on Social Work Practice
TI  - Effects of Multidimensional Family Therapy (MDFT) on Nonopioid Drug Abuse: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000417860300007
UR  - http://journals.sagepub.com/doi/10.1177/1049731515608241
UR  - http://journals.sagepub.com/doi/pdf/10.1177/1049731515608241
VL  - 28
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
This is an update of the original Cochrane Review published in Issue 4, 2011.Attention deficit hyperactivity disorder (ADHD) is the most prevalent of the comorbid psychiatric disorders that complicate tic disorders. Medications commonly used to treat ADHD symptoms include stimulants such as methylphenidate and amphetamine; non-stimulants, such as atomoxetine; tricyclic antidepressants; and alpha agonists. Alpha agonists are also used as a treatment for tics. Due to the impact of ADHD symptoms on the child with tic disorder, treatment of ADHD is often of greater priority than the medical management of tics. However, for many decades, clinicians have been reluctant to use stimulants to treat children with ADHD and tics for fear of worsening their tics. 

**OBJECTIVES: **
To assess the effects of pharmacological treatments for ADHD in children with comorbid tic disorders on symptoms of ADHD and tics.

**SEARCH METHODS:**
In September 2017, we searched CENTRAL, MEDLINE, Embase, and 12 other databases. We also searched two trial registers and contacted experts in the field for any ongoing or unpublished studies.

**SELECTION CRITERIA:**
We included randomized, double-blind, controlled trials of any pharmacological treatment for ADHD used specifically in children with comorbid tic disorders. We included both parallel-group and cross-over study designs.

**DATA COLLECTION AND ANALYSIS:**
We used standard methodological procedures of Cochrane, in that two review authors independently selected studies, extracted data using standardized forms, assessed risk of bias, and graded the overall quality of the evidence by using the GRADE approach.

**MAIN RESULTS:**
We included eight randomized controlled trials (four of which were cross-over trials) with 510 participants (443 boys, 67 girls) in this review. Participants in these studies were children with both ADHD and a chronic tic disorder. All studies took place in the USA and ranged from three to 22 weeks in duration. Five of the eight studies were funded by charitable organizations or government agencies, or both. One study was funded by the drug manufacturer. The other two studies did not specify the source of funding. Risk of bias of included studies was low for blinding; low or unclear for random sequence generation, allocation concealment, and attrition bias; and low or high for selective outcome reporting. We were unable to combine any of the studies in a meta-analysis due to important clinical heterogeneity and unit-of-analysis issues.Several of the trials assessed multiple agents. Medications assessed included methylphenidate, clonidine, desipramine, dextroamphetamine, guanfacine, atomoxetine, and deprenyl. There was low-quality evidence for methylphenidate, atomoxetine, and clonidine, and very low-quality evidence for desipramine, dextroamphetamine, guanfacine and deprenyl in the treatment of ADHD in children with tics. All studies, with the exception of a study using deprenyl, reported improvement in symptoms of ADHD. Tic symptoms also improved in children treated with guanfacine, desipramine, methylphenidate, clonidine, and a combination of methylphenidate and clonidine. In one study, tics limited further dosage increases of methylphenidate. High-dose dextroamphetamine appeared to worsen tics in one study, although the length of this study was limited to three weeks. There was appetite suppression or weight loss in association with methylphenidate, dextroamphetamine, atomoxetine, and desipramine. There was insomnia associated with methylphenidate and dextroamphetamine, and sedation associated with clonidine.

**AUTHORS&#039; CONCLUSIONS:**
Following an updated search of potentially relevant studies, we found no new studies that matched our inclusion criteria and thus our conclusions have not changed.Methylphenidate, clonidine, guanfacine, desipramine, and atomoxetine appear to reduce ADHD symptoms in children with tics though the quality of the available evidence was low to very low. Although stimulants have not been shown to worsen tics in most people with tic disorders, they may, nonetheless, exacerbate tics in individual cases. In these instances, treatment with alpha agonists or atomoxetine may be an alternative. Although there is evidence that desipramine may improve tics and ADHD in children, safety concerns will likely continue to limit its use in this population.
AU  - Osland,
AU  - S.
AU  - T.
AU  - Steeves,
AU  - T.
AU  - D.
AU  - L.
AU  - Pringsheim,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD007990.pub3
L1  - internal-pdf://3071635487/Osland_et_al-2018-Cochrane_Database_of_Systema.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders
ER  -
TY  - JOUR
AB  - The purpose of this systematic review was to investigate the effects of instruction on single-word reading of individuals who use aided augmentative and alternative communication (AAC). 

A systematic search identified nine single-case experimental design studies that involved 24 individuals who used aided AAC. Overall, the evidence indicated that instruction had positive effects on reading at the single-word level for individuals across ages and diagnostic categories (i.e., autism spectrum disorder (ASD), cerebral palsy (CP), Down syndrome, and intellectual disability).

The studies revealed that these effects were consistent across a range of participant, intervention, and outcome measure characteristics. Phonological approaches, sight-word approaches, and a combination of these two approaches yielded very large effects. 

Despite the large effects, the findings must be viewed with caution due to limitations in the number of studies and participants and limitations in the reporting of detailed participant and intervention characteristics across the studies. 

In order to determine which interventions are most effective for which individuals, future research directions are discussed, including the need for greater specificity in describing participant and intervention characteristics, investigations into how to best measure intervention outcomes without requiring spoken responses, and investigations into longer-term interventions targeting a wider range of reading skills.
AD  - [Mandak, Kelsey; Light, Janice; Boyle, Susannah] Penn State Univ, University Pk, PA 16802 USA.Mandak, K (reprint author), Penn State Univ, Dept Commun Sci &amp; Disorders, Ford Bldg, University Pk, PA 16802 USA.kch5029@psu.edu
AN  - WOS:000450570700004
AU  - Mandak,
AU  - K.
AU  - Light,
AU  - J.
AU  - Boyle,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/07434618.2018.1470668
J2  - Augment. Altern. Commun.
KW  - Systematic review
KW  - single-word reading
KW  - augmentative and alternative
KW  - communication (AAC)
KW  - alternative communication intervention
KW  - developmental-disabilities
KW  - direct instruction
KW  - speech production
KW  - subject research
KW  - students
KW  - children
KW  - recognition
KW  - awareness
KW  - autism
KW  - Audiology &amp; Speech-Language Pathology
KW  - Rehabilitation
L1  - internal-pdf://2178844196/Mandak-2018-The effects of literacy interventi.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: HA8UWTimes Cited: 1Cited Reference Count: 50Mandak, Kelsey Light, Janice Boyle, SusannahPenn State AAC Leadership Project, a doctoral training grant - U.S. Department of Education [H325D110008]; Rehabilitation Engineering Research Center on Augmentative and Alternative Communication (The RERC on AAC) - National Institute on Disability, Independent Living, and Rehabilitation (NIDILRR) within the Administration for Community Living (ACL) of the US D [90RE5017]Portions of this article were submitted by the first author in partial fulfillment of PhD requirements at The Pennsylvania State University Department of Communication Sciences and Disorders. This project was supported, in part, by funding from the (a) Penn State AAC Leadership Project, a doctoral training grant funded by U.S. Department of Education grant #H325D110008; and (b) Rehabilitation Engineering Research Center on Augmentative and Alternative Communication (The RERC on AAC), funded by grant #90RE5017 from the National Institute on Disability, Independent Living, and Rehabilitation (NIDILRR) within the Administration for Community Living (ACL) of the US Department of Health and Human Services (HHS).13Taylor &amp; francis ltdAbingdon1477-3848
PY  - 2018
SP  - 206-218
T2  - Augmentative and Alternative Communication
TI  - The effects of literacy interventions on single-word reading for individuals who use aided AAC: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000450570700004
UR  - https://www.tandfonline.com/doi/full/10.1080/07434618.2018.1470668
VL  - 34
ER  -
TY  - JOUR
AB  - Mindfulness interventions have increasingly been incorporated in elementary and high school classrooms to support students&#039; mental health and well-being; however, there is little research examining the specific factors contributing to the effectiveness of the interventions. 

The purpose of this meta-analysis was to examine the specific effects of and moderators contributing to school-based mindfulness interventions for mental health in youth. A systematic review of studies published in PsycINFO, ERIC, Social Work Abstracts, Social Services Abstracts, and CINAHL was conducted. A total of 24 studies (n = 3977) were included in the meta-analysis. 

Overall, mindfulness interventions were found to be helpful, with small to moderate significant effects pre-post intervention compared to control groups (Hedges&#039; g = 0.24, p &lt; .001); however, interventions that were delivered during late adolescence (15-18) and that consisted of combinations of various mindfulness activities had the largest effects on mental health and well-being outcomes. Furthermore, the effects on specific mindfulness and mental health outcomes differed according to whether the intervention was delivered by an outside facilitator compared to trained educators/teachers. 

These results suggest that individual differences and program characteristics can impact receptivity and effectiveness of mindfulness training. These findings represent a significant contribution as they can be used to inform future designs and applications of mindfulness terventions in the school setting.
AD  - [Carsley, Dana; Khoury, Bassam; Heath, Nancy L.] McGill Univ, Dept Educ &amp; Counselling Psychol, 3700 McTavish St, Montreal, PQ H3A 1Y2, Canada.Carsley, D (reprint author), McGill Univ, Dept Educ &amp; Counselling Psychol, 3700 McTavish St, Montreal, PQ H3A 1Y2, Canada.dana.carsley@mail.mcgill.ca
AN  - WOS:000433139500002
AU  - Carsley,
AU  - D.
AU  - Khoury,
AU  - B.
AU  - Heath,
AU  - N.
AU  - L.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s12671-017-0839-2
J2  - Mindfulness
KW  - Mindfulness
KW  - Meta-analysis
KW  - Mental health
KW  - School
KW  - Children
KW  - Adolescents
KW  - stress reduction
KW  - controlled-trial
KW  - special-issue
KW  - pilot trial
KW  - children
KW  - adolescents
KW  - program
KW  - students
KW  - anxiety
KW  - meditation
KW  - Psychology
KW  - Psychiatry
L1  - internal-pdf://0790883231/Carsley-2018-Effectiveness of Mindfulness Inte.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: GH1CLTimes Cited: 1Cited Reference Count: 72Carsley, Dana Khoury, Bassam Heath, Nancy L.18SpringerDordrecht1868-8535
PY  - 2018
SP  - 693-707
T2  - Mindfulness
TI  - Effectiveness of Mindfulness Interventions for Mental Health in Schools: a Comprehensive Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000433139500002
UR  - https://link.springer.com/article/10.1007%2Fs12671-017-0839-2
VL  - 9
ER  -
TY  - JOUR
AB  - This review of reviews presents an empirically based set of mean effect size distributions for judging the relative impact of the effects of universal mental health promotion and prevention programs for school-age youth (ages 5 through 18) across a range of program targets and types of outcomes. Mean effect size distributions were established by examining the findings from 74 meta-analyses of universal prevention and promotion programs that included more than 1100 controlled outcome studies involving over 490,000 school-age youth. The distributions of mean effect sizes from these meta-analyses indicated considerable variability across program targets and outcomes that differed substantially from Cohen&#039;s (1988, Statistical power analysis for the behavioral sciences (2nd ed.)) widely used set of conventions for assessing if effects are small, medium, or large. These updated mean effect size distributions will provide researchers, practitioners, and funders with more appropriate evidence-based standards for judging the relative effects of universal prevention programs for youth. Limitations in current data and directions for future work are also discussed.
AD  - Tanner-Smith, Emily E. Department of Counseling Psychology and Human Services, University of Oregon, Eugene, OR, USA. etanners@uoregon.edu.Durlak, Joseph A. Loyola University Chicago, Chicago, IL, USA.Marx, Robert A. Department of Human and Organizational Development, Vanderbilt University, Nashville, TN, USA.
AN  - 30136245
AU  - Tanner-Smith,
AU  - E.
AU  - E.
AU  - Durlak,
AU  - J.
AU  - A.
AU  - Marx,
AU  - R.
AU  - A.
DA  - 11
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1007/s11121-018-0942-1
DP  - Ovid Technologies
J2  - Prev Sci
KW  - Adolescent
KW  - Child
KW  - Child, Preschool
KW  - Female
KW  - Humans
KW  - Male
KW  - Mental Disorders/pc [Prevention &amp; Control]
KW  - *Mental Health
KW  - *Preventive Health Services/og [Organization &amp; Administration]
KW  - *School Health Services/og [Organization &amp; Administration]
KW  - Schools
KW  - Substance-Related Disorders/pc [Prevention &amp; Control]
L1  - internal-pdf://2890197669/Tanner-Smith-2018.pdf
LA  - English
M3  - Meta-Analysis
Review
N1  - Tanner-Smith, Emily EDurlak, Joseph AMarx, Robert A
PY  - 2018
SP  - 1091-1101
T2  - Prevention Science
TI  - Empirically Based Mean Effect Size Distributions for Universal Prevention Programs Targeting School-Aged Youth: A Review of Meta-Analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=30136245
UR  - https://link.springer.com/article/10.1007%2Fs11121-018-0942-1
VL  - 19
ER  -
TY  - JOUR
AB  - Våld och f&ouml;rsummelse av barn som sker inom familjen &auml;r ett omfattande problem med allvarliga konsekvenser. Det beh&ouml;vs kunskap om evidensbaserade metoder f&ouml;r att arbeta med familjer d&auml;r våld och f&ouml;rsummelse f&ouml;rekommer. I denna rapport anv&auml;nder vi genomgående samlingsbegreppet &rdquo;våld och f&ouml;rsummelse&rdquo; f&ouml;r olika typ av utsatthet mot barn inom familjen.

**Slutsatser**
En enk&auml;tunders&ouml;kning har genomf&ouml;rts inom socialtj&auml;nsten och barn- och ungdomspsykiatrin i Sverige. Den visar att bara ett fåtal av insatser riktade till familjer d&auml;r det f&ouml;rekommer våld och f&ouml;rsummelse av barn har unders&ouml;kts i forskningsstudier som g&ouml;r det m&ouml;jligt att bed&ouml;ma effekterna av insatserna. SBU:s bed&ouml;mning &auml;r att b&auml;ttre kunskap om insatsernas effekter skulle ge f&ouml;ruts&auml;ttningar f&ouml;r att f&auml;rre barn uts&auml;tts f&ouml;r våld och f&ouml;rsummelse.

Våld och f&ouml;rsummelse av barn upp till skolåldern kan minska med hj&auml;lp av insatserna Project Support och Parent Child Interaction Therapy (PCIT).

Insatserna Project Support och PCIT kan leda till att barnens utagerande beteende minskar. PCIT kan också f&ouml;rb&auml;ttra samspelet mellan barn och f&ouml;r&auml;ldrar. Insatser som riktas mot små barns anknytning till vårdnadshavaren, till exempel Attachment and Biobehavioral Catch-up (ABC), kan leda till att f&auml;rre barn får så kallad desorganiserad anknytning som &auml;r f&ouml;rknippat med senare utveckling av psykisk oh&auml;lsa och kamratsvårigheter.

Behandlingskostnaderna f&ouml;r Project Support &auml;r något h&ouml;gre per familj &auml;n PCIT. Project Support kan m&ouml;jligen leda till att några fler barn inte uts&auml;tts f&ouml;r fortsatt våld i familjen efter insatsen, så kostnaden per barn med mindre våld i familjen blir snarlik f&ouml;r de två programmen.

Vid en samlad bed&ouml;mning menar SBU att val av insats beh&ouml;ver g&ouml;ras utifrån barnets och familjens f&ouml;ruts&auml;ttningar och behov, till exempel barnets ålder, vad barnet varit utsatt f&ouml;r och hur detta påverkar barnets psykiska h&auml;lsa och sociala relationer. N&auml;r en ny insats introduceras &auml;r det viktigt att beakta vilket vetenskapligt st&ouml;d det finns f&ouml;r insatsen. Vid planering och genomf&ouml;rande av insatser beh&ouml;ver barnets r&auml;ttigheter enligt g&auml;llande lagstiftning i Sverige samt barnkonventionen beaktas.

Studier med kvalitativ forskningsmetodik visar att f&ouml;r&auml;ldrar upplever att &ouml;ppenvårdsinsatser hj&auml;lper dem att hantera situationer med sina barn, men att insatserna inte alltid matchar deras individuella behov. En respektfull och f&ouml;rtroendefull relation med personalen lyfts fram som viktigt, liksom en v&auml;lkomnande milj&ouml; d&auml;r insatsen genomf&ouml;rs. F&ouml;r&auml;ldrar upplever att de beh&ouml;ver st&ouml;d &auml;ven efter en insats. Det finns f&ouml;r få studier som redovisar barns upplevelser f&ouml;r att kunna dra några slutsatser.

Enligt rapporter från brukarf&ouml;reningar ber&auml;ttar barn och unga som av olika anledningar haft kontakter med socialtj&auml;nsten, att de saknar st&ouml;d f&ouml;r att hantera svåra upplevelser. De upplever också att insatser ges f&ouml;r sent i livet och att de inte får den information de beh&ouml;ver om vilken hj&auml;lp de kan få. Dessa ber&auml;ttelser lyfter fram f&ouml;rhållanden som kan strida mot svensk lagstiftning och mot barnkonventionen.

Inom forskningen beh&ouml;ver man anv&auml;nda mer enhetliga mått på effekt f&ouml;r att g&ouml;ra det m&ouml;jligt att j&auml;mf&ouml;ra resultat från olika studier. Detta skulle &auml;ven underl&auml;tta tolkning av kostnadseffektivitet. Framtida studier b&ouml;r unders&ouml;ka insatsers effekt på våld och f&ouml;rsummelse. Studierna beh&ouml;ver omfatta fler deltagare och ha l&auml;ngre uppf&ouml;ljningstid. Vidare b&ouml;r t&auml;nkbara negativa effekter av &ouml;ppenvårdsinsatser unders&ouml;kas. Vid planering av forskning beh&ouml;ver barnets r&auml;ttigheter utifrån barnkonventionen beaktas.

**Bakgrund och syfte**
Mellan 3 och 9 procent av barnen i de nordiska l&auml;nderna uts&auml;tts f&ouml;r direkt våld i hemmet och mellan 7 och 12 procent har bevittnat våld i hemmet. Konsekvenserna av att uts&auml;ttas f&ouml;r våld och f&ouml;rsummelse under barndomen &auml;r allvarliga. Forskningen visar att det kan påverka hj&auml;rnans utveckling negativt samt &ouml;ka de långsiktiga riskerna f&ouml;r bland annat depression, ångest, missbruk och sj&auml;lvmordsf&ouml;rs&ouml;k. Kunskap beh&ouml;vs om vilka insatser som &auml;r effektiva f&ouml;r familjer d&auml;r barn och unga uts&auml;tts f&ouml;r våld och f&ouml;rsummelse.Syftet med denna rapport &auml;r att sammanst&auml;lla det vetenskapliga underlaget om effekter och kostnadseffektivitet av &ouml;ppenvårdsinsatser till familjer d&auml;r det f&ouml;rekommer våld och f&ouml;rsummelse mot barn, samt om hur f&ouml;r&auml;ldrar och barn upplever att delta i insatser.

**Metod**
Denna utv&auml;rdering omfattar tre delar a) en utv&auml;rdering av effekter av &ouml;ppenvårdsinsatser baserat på studier med kvantitativ metod b) en utv&auml;rdering av barns och f&ouml;r&auml;ldrars upplevelser av &ouml;ppenvårdsinsatser baserat på studier med kvalitativ metod och c) en utv&auml;rdering av kostnadseffektiviteten baserat på ekonomiska studier. I &ouml;vrigt innehåller utv&auml;rderingen en enk&auml;tunders&ouml;kning f&ouml;r att kartl&auml;gga vilka insatser som anv&auml;nds inom social- och barnpsykiatrisk &ouml;ppenvård, ett kapitel om barns och ungas upplevelser utifrån brukarrapporter, samt ett kapitel d&auml;r etiska och barnr&auml;ttsliga aspekter diskuteras.

&Ouml;ppenvårdsinsatserna ska vara indikerade, det vill s&auml;ga ges n&auml;r man vet eller misst&auml;nker att våld och f&ouml;rsummelse mot barn f&ouml;rekommer. Insatserna ska kunna genomf&ouml;ras inom social- eller barnpsykiatrisk &ouml;ppenvård, individuellt eller i grupp. De kvantitativa studierna ska innehålla en kontrollgrupp och ha en f&ouml;r- och efterm&auml;tning. Studier med kvalitativ metodik ska bygga på intervjuer med barn eller f&ouml;r&auml;ldrar. Både kvantitativa och kvalitativa studier ska vara genomf&ouml;rda med tillr&auml;ckligt god kvalitet.I de ekonomiska aspekterna ingår, f&ouml;rutom en systematisk litteraturgenomgång, en ber&auml;kning av behandlingskostnaderna f&ouml;r några manualbaserade insatser och kostnadseffektanalyser av tre insatser med ett begr&auml;nsat vetenskapligt st&ouml;d. Kostnadseffektanalyserna j&auml;mf&ouml;r behandlingskostnaderna med projektets effekter, uttryckt som antal barn av hundra som har fått en b&auml;ttre situation.

**Effekter av &ouml;ppenvårdsinsatser**
Litteraturs&ouml;kningen identifierade 11 386 artiklar. Av dessa bed&ouml;mdes 33 randomiserade kontrollerade studier (RCT:er) uppfylla kraven på relevans och kvalitet f&ouml;r att inkluderas i rapporten. Studierna unders&ouml;kte tio manualbaserade insatser och fyra insatser som inte baserats på en manual. SBU:s utv&auml;rdering kunde visa att tre av de manualbaserade insatserna hade effekt (Begr&auml;nsat vetenskapligt underlag). Hos familjer med barn upp till skolåldern som deltagit i insatserna Project Support och Parent Child Interaction Therapy (PCIT) var det f&auml;rre anm&auml;lningar om våld och f&ouml;rsummelse samt mindre utagerande beteende hos barn, j&auml;mf&ouml;rt med familjer som fått sedvanlig insats. I granskningen fann vi &auml;ven att anknytningsbaserade insatser, till exempel Attachment and Biobehavioral Catch-up (ABC) minskade risken f&ouml;r att små barn skulle utveckla en desorganiserad anknytning, j&auml;mf&ouml;rt med barn d&auml;r sedvanliga insatser erbjudits.

F&ouml;r flera manualbaserade insatser till f&ouml;r&auml;ldrar och barn gick det inte att avg&ouml;ra om insatsen hade någon effekt: dessa var Kognitiv Integrerad Behandling vid Barnmisshandel (KIBB), Multisystemisk terapi vid våld och f&ouml;rsummelse mot barn (MST-CAN), Kids Club och Moms Empowerment Program (MEP), Traumafokuserad Kognitiv Beteendeterapi (TF-KBT), Child Parent Psychotherapy (CPP), Family Behavior Therapy (FBT) och Enhanced Group Behavioral Family Intervention (EBFI). Avsaknaden av vetenskapligt st&ouml;d inneb&auml;r att vi inte vet om insatsen har positiva eller negativa effekter, eller inga effekter alls. Forskningsl&auml;get om dessa insatser &auml;r idag oklart f&ouml;r målgruppen barn som varit utsatta f&ouml;r våld och f&ouml;rsummelse. F&ouml;r flera av insatserna finns det dock exempel på svenska genomf&ouml;rbarhetsstudier.

**Ekonomiska aspekter**
Behandlingskostnaderna per familj (en f&ouml;r&auml;lder och ett barn) f&ouml;r sju manualbaserade program varierade mellan 3 800 och 25 700 kronor. Programmet Kid&rsquo;s Club, med l&auml;gst kostnad genomf&ouml;rs i grupp, så kostnaderna f&ouml;r socialtj&auml;nsten blir s&auml;rskilt låga. Insatser med många och långa behandlingssessioner, som KIBB och TF-KBT, blir kostsamma både f&ouml;r socialtj&auml;nsten och totalt f&ouml;r samh&auml;llet. I de totala samh&auml;llskostnaderna ingår &auml;ven f&ouml;r&auml;ldrarnas och barnens tid, men inga besparingar på l&auml;ngre sikt på grund av minskat våld och f&ouml;rsummelse av barn.

Tre av insatserna hade minst ett begr&auml;nsat vetenskapligt underlag m&auml;tt i utfallsmått som kan anv&auml;ndas f&ouml;r ekonomiska utv&auml;rderingar. F&ouml;r PCIT och Project Support finns ett gemensamt utfallsmått: andelen barn med minskat våld inom familjen, så de programmen kan j&auml;mf&ouml;ras sinsemellan. Behandlingen av 100 barn med PCIT ber&auml;knades kosta 1,27 miljoner kronor (0,7 miljoner f&ouml;r socialtj&auml;nsten), så kostnaden per barn med minskat våld inom familjen (15 av 100) blir 85 000 kronor (48 000 kronor f&ouml;r socialtj&auml;nsten). Motsvarande kostnader f&ouml;r Project Support &auml;r 1,44 miljoner kronor (varav 1 miljon f&ouml;r socialtj&auml;nsten), med en kostnad per barn med minskat våld inom familjen (19 av 100) på 76 000 kronor (53 000 f&ouml;r socialtj&auml;nsten). Med tanke på den os&auml;kerhet som finns i underlaget avseende skillnaden i effekt mellan de två programmen kan Project Support och PCIT anses likv&auml;rdiga.

Den systematiska genomgången av den internationella ekonomiska litteraturen kunde inte identifiera någon studie med r&auml;tt studiepopulation av tillr&auml;ckligt h&ouml;g metodologisk kvalitet och &ouml;verf&ouml;rbarhet till svenska f&ouml;rhållanden.

**Barns och f&ouml;r&auml;ldrars upplevelser av &ouml;ppenvårdsinsatser**
Sammanlagt fann vi 12 studier d&auml;r man intervjuat f&ouml;r&auml;ldrar och d&auml;r intervjuerna analyserats med kvalitativ analysmetodik. Vi fann endast två studier av tillr&auml;ckligt god kvalitet som har unders&ouml;kt barnens upplevelser av insatser till familjen. F&ouml;r&auml;ldrar upplever att en insats kan bidra till b&auml;ttre f&ouml;r&auml;ldrastrategier, men att insatserna inte alltid matchar familjernas specifika behov. F&ouml;r&auml;ldrar upplever &auml;ven att gruppformat inneb&auml;r igenk&auml;nnande och fyller en social funktion, men passar inte alla. Personalens f&ouml;rmåga att visa tillit, f&ouml;rmedla v&auml;rme och respektera integritet uppgavs &auml;ven som viktigt, liksom milj&ouml;n d&auml;r insatsen genomf&ouml;rs. F&ouml;r&auml;ldrar efterfrågar &auml;ven tillgången till praktiskt st&ouml;d både under och efter en insats.

**Barn och ungdomar ber&auml;ttar**
I rapporter från brukarorganisationer ber&auml;ttar barn och ungdomar om sina kontakter med socialtj&auml;nsten. De upplever att de saknar st&ouml;d av vuxna professionella med att bearbeta svåra upplevelser. Barnen och ungdomarna ber&auml;ttar att insatser som de har tagit del av s&auml;llan fyller deras behov av st&ouml;d, att insatser ges f&ouml;r sent i deras liv, att de inte får g&ouml;ra sin r&ouml;st h&ouml;rd under familjebehandling och att skuld och ansvar l&auml;ggs på barnen. Dessa ber&auml;ttelser lyfter fram f&ouml;rhållanden som kan strida mot svensk lagstiftning och mot barns r&auml;ttigheter enligt barnkonventionen.


**Svensk praxis**
F&ouml;r att unders&ouml;ka vilka insatser som anv&auml;nds inom svensk socialtj&auml;nst och barn- och ungdomspsykiatrin (BUP) skickades enk&auml;ter till 290 kommuner och 4 stadsdelar i Sverige samt till 35 verksamhetschefer inom barn- och ungdomspsykiatrin (BUP) vid samtliga landsting. Sammanlagt svarade 137 kommuner (47 %) och 13 BUP-mottagningar (39 %) på enk&auml;ten. Dessa uppgav att de anv&auml;nde 27 respektive 22 olika &ouml;ppenvårdsinsatser f&ouml;r målgruppen familjer d&auml;r det f&ouml;rekommer våld och f&ouml;rsummelse. Den absoluta majoriteten av dessa insatser har inte pr&ouml;vats vetenskapligt f&ouml;r den aktuella målgruppen, varken internationellt eller under svenska f&ouml;rhållanden. Det råder alltså brist på kunskap om insatserna &auml;r effektiva, verkningsl&ouml;sa eller skadliga.

**Barnr&auml;ttsliga och etiska aspekter**
Rapporten har f&ouml;r avsikt att ha ett &ouml;vergripande barnperspektiv d&auml;r vi i olika delar i rapporten knyter an till barnets r&auml;ttigheter enligt barnkonventionen. Trots att studierna som inkluderats i denna rapport håller relativt god kvalitet och &auml;r v&auml;lskrivna saknar de genomgående etiska och barnr&auml;ttsliga diskussioner.I studierna borde man också ha f&ouml;rv&auml;ntat sig tydligare diskussioner om social r&auml;ttvisa, exempelvis: Vem &auml;r insatsen huvudsakligen riktad till och vilka har exkluderats? Har &auml;ven barnen gett informerat samtycke till att delta i insatsen? Har insatsen negativa effekter? &Auml;r insatsernas kostnader rimliga eller skulle man kunnat anv&auml;nda resurserna på ett b&auml;ttre s&auml;tt? Har resurserna anv&auml;nts till att hj&auml;lpa så många barn som m&ouml;jligt? De insatser som inf&ouml;rts eller som man avser att inf&ouml;ra i Sverige b&ouml;r analyseras från både ett etiskt och barnr&auml;ttsligt perspektiv.

**Diskussion**
Endast ett fåtal av de &ouml;ppenvårdsinsatser som anv&auml;nds vid våld och f&ouml;rsummelse mot barn i Sverige har utv&auml;rderats. F&ouml;r insatserna Project Support och Parent Child Interaction Therapy (PCIT) finns det ett begr&auml;nsat vetenskapligt underlag f&ouml;r att insatserna kan minska våld och f&ouml;rsummelse inom familjen. Kostnaderna per barn som slipper fortsatt våld f&ouml;r de två insatserna &auml;r t&auml;mligen låga, s&auml;rskilt i j&auml;mf&ouml;relse med m&ouml;jliga minskningar i framtida samh&auml;llskostnader om våld och f&ouml;rsummelse av barn kan f&ouml;rebyggas. Project Support har &auml;ven rapporterats fungera avseende programtrohet och acceptans av behandlare och f&ouml;r&auml;ldrar i en svensk genomf&ouml;rbarhetsstudie. Gemensamt f&ouml;r dessa insatser &auml;r att de riktar sig till yngre barn och bland annat utgår från systematisk tr&auml;ning av f&ouml;r&auml;ldraf&ouml;rmågor genom exempelvis rollspel och f&ouml;r&auml;ldra- och barninteraktion, f&ouml;r att f&ouml;rb&auml;ttra samspelet. Project Support innehåller &auml;ven praktiskt och emotionellt st&ouml;d till f&ouml;r&auml;ldrarna. F&ouml;r ett flertal av de utv&auml;rderade insatserna i denna rapport &auml;r det vetenskapliga st&ouml;det otillr&auml;ckligt. Detta inneb&auml;r inte att de &auml;r ineffektiva och att man per automatik ska sluta anv&auml;nda dem. Det inneb&auml;r att vi inte vet om de &auml;r effektiva, saknar effekt eller har negativa effekter. De beh&ouml;ver utv&auml;rderas systematiskt i svenska f&ouml;rhållanden.Val av insats beh&ouml;ver g&ouml;ras utifrån barnets och familjens f&ouml;ruts&auml;ttningar och behov, och barnets behov av skydd ska vara tillgodosett. En insats vetenskapliga st&ouml;d och resursåtgång beh&ouml;ver vara en viktig urvalsgrund vid val av insats. Vidare &auml;r en enstaka manualbaserad insats s&auml;llan tillr&auml;cklig, framf&ouml;r allt inte f&ouml;r familjer med multiproblematik. Familjerna &auml;r ofta i behov av fortsatt socialt och praktiskt st&ouml;d. F&ouml;r&auml;ldrarna kan beh&ouml;va motiveras f&ouml;r att delta i en insats och arbeta med sina problem. Tid och plats f&ouml;r insatserna kan beh&ouml;va anpassas efter familjens f&ouml;ruts&auml;ttningar. Behandlarna beh&ouml;ver kontinuerlig handledning, st&ouml;d och utbildning f&ouml;r att kunna arbeta med, samt implementera insatserna. Barn som utsatts f&ouml;r våld och f&ouml;rsummelse efterfrågar st&ouml;d och behandling, att insatserna inte kommer f&ouml;rsent i deras liv och att få vara delaktiga i beslut och planering av behandlingen. Detta &auml;r r&auml;ttigheter som &auml;r reglerade i svensk lagstiftning och i barnkonventionen (de tre p:na: Provision (behov), Protection (skydd) och Participation (delaktighet)).
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /sv/publikationer/SBU-utvarderar/oppenvardsinsatser-for-familjer-dar-barn-utsatts-for-vald-och-forsummelse/
L1  - internal-pdf://2232531740/oppenvardsinsatser_familjer_barn_utsatts_vald_.pdf
PY  - 2018
TI  - &Ouml;ppenvårdsinsatser f&ouml;r familjer d&auml;r barn uts&auml;tts f&ouml;r våld och f&ouml;rsummelse. En systematisk &ouml;versikt och utv&auml;rdering inklusive ekonomiska och etiska aspekter.
ER  -
TY  - JOUR
AB  - This meta-analytic review evaluates 35 parenting programs to analyze their effectiveness at reducing young children&#039;s externalizing behavior (EB). It looks at whether behavioral or cognitive orientation, informant or duration of these programs moderate their effect on such young children. 

It confirms that parenting interventions are effective at decreasing young children&#039;s EB but no moderation effect was found for specific orientation or duration, only for the informant.

This illustrates the current difficulty in comparing programs on the basis of their theoretical background, which prevents the understanding of which are the most efficient parenting variables and change processes to manipulate. 

(PsycINFO Database Record (c) 2019 APA, all rights reserved)
AN  - 2018-33804-001
AU  - Mouton,
AU  - Benedicte
AU  - Loop,
AU  - Laurie
AU  - Stievenart,
AU  - Marie
AU  - Roskam,
AU  - Isabelle
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/07317107.2018.1477348
L1  - internal-pdf://0799911781/Mouton-2018-Parenting programs to reduce young.pdf
PY  - 2018
SP  - 115-147
T2  - Child &amp; Family Behavior Therapy
TI  - Parenting programs to reduce young children&#039;s externalizing behavior: A meta-analytic review of their behavioral or cognitive orientation
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2018-33804-001
UR  - https://www.tandfonline.com/doi/pdf/10.1080/07317107.2018.1477348?needAccess=true
VL  - 40
ER  -
TY  - JOUR
AB  - **CONTEXT: **
Nonpharmacologic treatments for attention-deficit/hyperactivity disorder (ADHD) encompass a range of care approaches from structured behavioral interventions to complementary medicines. 

**OBJECTIVES: **
To assess the comparative effectiveness of nonpharmacologic treatments for ADHD among individuals 17 years of age and younger. 

**DATA SOURCES: **
PubMed, Embase, PsycINFO, and Cochrane Database of Systematic Reviews for relevant English-language studies published from January 1, 2009 through November 7, 2016. 

**STUDY SELECTION: **
We included studies that compared any ADHD nonpharmacologic treatment strategy with placebo, pharmacologic, or another nonpharmacologic treatment. 

**DATA EXTRACTION: **
Study design, patient characteristics, intervention approaches, follow-up times, and outcomes were abstracted. For comparisons with at least 3 similar studies, random-effects meta-analysis was used to generate pooled estimates. 

**RESULTS:** 
We identified 54 studies of nonpharmacologic treatments, including neurofeedback, cognitive training, cognitive behavioral therapy, child or parent training, dietary omega fatty acid supplementation, and herbal and/or dietary approaches. No new guidance was identified regarding the comparative effectiveness of nonpharmacologic treatments. Pooled results for omega fatty acids found no significant effects for parent rating of ADHD total symptoms (n = 411; standardized mean difference -0.32; 95% confidence interval -0.80 to 0.15; I-2 = 52.4%; P = .10) or teacher-rated total ADHD symptoms (n = 287; standardized mean difference -0.08; 95% confidence interval -0.47 to 0.32; I-2 = 0.0%; P = .56). 

**LIMITATIONS: **
Studies often did not reflect the primary care setting and had short follow-up periods, small sample sizes, variations in outcomes, and inconsistent reporting of comparative statistical analyses. 

**CONCLUSIONS: **
Despite wide use, there are significant gaps in knowledge regarding the effectiveness of ADHD nonpharmacologic treatments.
AD  - [Maslow, Gary R.; Davis, Naomi; Hill, Sherika; Namdari, Behrouz] Duke Univ, Sch Med, Dept Psychiat &amp; Behav Sci, Durham, NC USA. [Maslow, Gary R.] Duke Univ, Dept Pediat, Sch Med, Durham, NC 27706 USA. [LaPointe, Nancy M. Allen] Duke Univ, Sch Med, Dept Med, Durham, NC 27706 USA. [Goode, Adam P.] Duke Univ, Sch Med, Duke Orthopaed Surg, Durham, NC 27706 USA. [Goode, Adam P.; Lallinger, Kathryn R.; Kosinski, Andrzej; McBroom, Amanda J.; Sanders, Gillian D.] Duke Univ, Sch Med, Duke Clin Res Inst, Durham, NC 27706 USA. [Bowen, Samantha E.] Duke Univ, Sch Med, Duke Ctr Autism &amp; Brain Dev, Durham, NC 27706 USA. [Coeytaux, Remy R.] Wake Forest Univ, Sch Med, Dept Family &amp; Community Med, Winston Salem, NC 27109 USA. [Coeytaux, Remy R.; Befus, Deanna] Wake Forest Univ, Sch Med, Ctr Integrat Med, Winston Salem, NC 27109 USA. [LaPointe, Nancy M. Allen] Premier Inc, Charlotte, NC USA. [Lallinger, Kathryn R.; McBroom, Amanda J.; Sanders, Gillian D.] Duke Evidence Based Practice Ctr, Durham, NC USA. [Kemper, Alex R.] Nationwide Childrens Hosp, Div Ambulatory Pediat, 700 Childrens Dr,LAC5411, Columbus, OH 43205 USA.Kemper, AR (reprint author), Nationwide Childrens Hosp, Div Ambulatory Pediat, 700 Childrens Dr,LAC5411, Columbus, OH 43205 USA.alex.kemper@nationwidechildrens.org
AN  - WOS:000437406200040
AU  - Goode,
AU  - A.
AU  - P.
AU  - Coeytaux,
AU  - R.
AU  - R.
AU  - Maslow,
AU  - G.
AU  - R.
AU  - Davis,
AU  - N.
AU  - Hill,
AU  - S.
AU  - Namdari,
AU  - B.
AU  - LaPointe,
AU  - N.
AU  - M.
AU  - A.
AU  - Befus,
AU  - D.
AU  - Lallinger,
AU  - K.
AU  - R.
AU  - Bowen,
AU  - S.
AU  - E.
AU  - Kosinski,
AU  - A.
AU  - McBroom,
AU  - A.
AU  - J.
AU  - Sanders,
AU  - G.
AU  - D.
AU  - Kemper,
AU  - A.
AU  - R.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2018-0094
J2  - Pediatrics
KW  - randomized controlled-trial
KW  - deficit hyperactivity disorder
KW  - placebo-controlled trial
KW  - family-school intervention
KW  - prospective
KW  - follow-up
KW  - open-label extension
KW  - omega3 fatty-acids
KW  - double-blind
KW  - clinical-trial
KW  - young-children
KW  - Pediatrics
L1  - internal-pdf://4109958780/Goode-2018-Nonpharmacologic Treatments for Att.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GL7TDTimes Cited: 0Cited Reference Count: 78Goode, Adam P. Coeytaux, Remy R. Maslow, Gary R. Davis, Naomi Hill, Sherika Namdari, Behrouz LaPointe, Nancy M. Allen Befus, Deanna Lallinger, Kathryn R. Bowen, Samantha E. Kosinski, Andrzej McBroom, Amanda J. Sanders, Gillian D. Kemper, Alex R.Duke Evidence-based Practice Center [HHSA290201500004I]; National Institute of Child Health and Human Development (Hill) through the Center for Developmental Science, University of North Carolina at Chapel Hill [T32-HD07376]; Agency for Healthcare Research and Quality, US Department of Health and Human Services [HHSA290201500004I]This report is based on research conducted by the Duke Evidence-based Practice Center under contract to the Agency for Healthcare Research and Quality, Rockville, Maryland (Contract HHSA290201500004I). Supported also in part by the National Institute of Child Health and Human Development (Hill, T32-HD07376) through the Center for Developmental Science, University of North Carolina at Chapel Hill. Funded under Contract No. HHSA290201500004I Task Order 2 from the Agency for Healthcare Research and Quality, US Department of Health and Human Services.0Amer acad pediatricsElk grove village1098-4275
PY  - 2018
SP  - 12
T2  - Pediatrics
TI  - Nonpharmacologic Treatments for Attention-Deficit/Hyperactivity Disorder: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000437406200040
UR  - http://pediatrics.aappublications.org/content/141/6/e20180094
VL  - 141
ER  -
TY  - JOUR
AB  - **Background: **
Various clinical trials suggested that risperidone was beneficial in the treatment of autism spectrum disorder (ASD) in children and adolescents. 

**Objective:**
The aim of this systematic review was to determine the efficacy, acceptability and tolerability of risperidone in the treatment of children and adolescents with ASD. 

**Data sources:**
The databases of Scopus, PubMed, CINAHL and Cochrane Controlled Trials Register were searched in February 2017. Study eligibility criteria, participants and interventions: Eligible RCTs of risperidone in the treatment of child and adolescent patients with ASD. Languages were not restricted. 

**Study appraisal and synthesis methods: **
The full-text versions of relevant studies were thoroughly assessed and extracted. The primary efficacy of outcome was the pooled response rate and the pooled mean changed scores of the standardized rating scales for ASD. 

**Results: **
A total of 372 randomized subjects from seven RCTs were included in this review. In acute treatment, the pooled mean change score of the Aberrant Behavior Checklist for irritability subscale (ABC-I) and response rate for the risperidone-treated group had a greater significance than that of the placebo-treated group. In the long-term treatment, the pooled mean change score of the CARS in the risperidone-treated group was significantly greater than that in the placebo-treated group. According to the discontinuation phase, the overall pooled relapse rate of the risperidone-treated group was significantly less than that of the placebo-treated group. The rates of pooled overall discontinuation and discontinuation due to adverse events rates were not different between the two groups in acute and long-term treatments. 

**Limitations: **
A small study was included in the current review. 

**Conclusion: **
In relation to the current systematic review, risperidone is efficacious in the treatment of symptoms in children and adolescents with ASD. Although its acceptability is comparable to placebo, treatment with risperidone is well tolerated in children and adolescents with ASD.
AD  - [Maneeton, Narong; Maneeton, Benchalak; Narkpongphun, Assawin; Srisurapanont, Manit] Chiang Mai Univ, Dept Psychiat, Fac Med, 110 Intawaroros Rd, Chiang Mai 50200, Thailand. [Putthisri, Suwannee] Mahidol Univ, Ramathibodi Hosp, Dept Psychiat, Fac Med, Bangkok, Thailand. [Woottiluk, Pakapan] Chiang Mai Univ, Fac Nursing, Psychiat Nursing Div, Chiang Mai, Thailand.Maneeton, N (reprint author), Chiang Mai Univ, Dept Psychiat, Fac Med, 110 Intawaroros Rd, Chiang Mai 50200, Thailand.narong.m@cmu.ac.th
AN  - WOS:000438312800001
AU  - Maneeton,
AU  - N.
AU  - Maneeton,
AU  - B.
AU  - Putthisri,
AU  - S.
AU  - Woottiluk,
AU  - P.
AU  - Narkpongphun,
AU  - A.
AU  - Srisurapanont,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2147/ndt.S151802
J2  - Neuropsychiatr. Dis. Treat.
KW  - Aberrant Behavior Checklist
KW  - ABC
KW  - Childhood Autism Rating Scale
KW  - CARS
KW  - efficacy
KW  - acceptability
KW  - tolerability
KW  - pervasive developmental disorders
KW  - randomized clinical-trial
KW  - behavioral
KW  - symptoms
KW  - double-blind
KW  - preschool-children
KW  - haloperidol
KW  - efficacy
KW  - prevalence
KW  - metaanalysis
KW  - safety
KW  - Neurosciences &amp; Neurology
KW  - Psychiatry
L1  - internal-pdf://1812010505/Maneeton-2018-Risperidone for children and ado.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GM6UUTimes Cited: 0Cited Reference Count: 40Maneeton, Narong Maneeton, Benchalak Putthisri, Suwannee Woottiluk, Pakapan Narkpongphun, Assawin Srisurapanont, ManitSrisurapanont, Manit/0000-0001-6203-12060Dove medical press ltdAlbany
PY  - 2018
SP  - 1811-1820
T2  - Neuropsychiatric Disease and Treatment
TI  - Risperidone for children and adolescents with autism spectrum disorder: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000438312800001
UR  - https://www.dovepress.com/getfile.php?fileID=43079
VL  - 14
ER  -
TY  - JOUR
AB  - Social anxiety disorder (SAD) is highly prevalent and persistent in children and adolescents. However, evidence for the efficacy and acceptability of psychological interventions for SAD in children and adolescents remains unclear. Seven electronic databases (PubMed, CENTRAL, Embase, Web of Science, PsycINFO, CINAHL, and ProQuest) were searched. Randomized controlled trials (RCTs) that compared psychological interventions for SAD with control conditions in children and adolescents were included. 

Primary outcomes were the efficacy (mean change in anxiety symptom scores) and acceptability (dropouts for all reasons). Secondary outcomes were remission, quality of life/functional improvement, and depressive symptoms measures. Seventeen RCTs were included in this meta-analysis. 

Psychological interventions (including cognitive behavioral therapy and behavioral therapy) were significantly more effective than control conditions, with a standardized mean difference (SMD) of - 1.13, and remission with a risk ratio (RR) of 8.99, the number needed to treat was 3.3. 

There was no statistically significant difference between psychological interventions and control conditions for all-cause dropouts (RR = 1.00). Psychological interventions were superior to control conditions in improving quality of life/functioning (SMD = 0.79) and reducing depressive symptoms (SMD = - 0.39). Given considerable heterogeneity of primary efficacy outcome, a series of subgroup analyses of different variables were conducted. 

Psychological interventions are probably efficacious in the treatment of SAD among children and adolescents, and may markedly improve quality of life and functioning in this population. However, this finding should be interpreted with caution because of the high heterogeneity of trials and low literature quality. 

Copyright &copy; 2018 Springer-Verlag GmbH Germany, part of Springer Nature
AD  - (Yang, Pu, Liu, Zhang, Zhang, Yuan, Teng, Tian, Xie) Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, China (Zhou) Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China (Cuijpers) Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Van der Boechorststraat 1, Amsterdam 1081 BT, NetherlandsP. Xie, Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Yixueyuan Road, Yuzhong District, Chongqing 400016, China. E-mail: xiepeng973@126.com
AN  - 623034228
AU  - Yang,
AU  - L.
AU  - Zhou,
AU  - X.
AU  - Pu,
AU  - J.
AU  - Liu,
AU  - L.
AU  - Cuijpers,
AU  - P.
AU  - Zhang,
AU  - Y.
AU  - Zhang,
AU  - H.
AU  - Yuan,
AU  - S.
AU  - Teng,
AU  - T.
AU  - Tian,
AU  - L.
AU  - Xie,
AU  - P.
DA  - 13 Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00787-018-1189-x
DP  - Ovid Technologies
KW  - Adolescent
KW  - Child
KW  - Meta-analysis
KW  - Psychological intervention
KW  - Social anxiety disorder
KW  - article
KW  - cognitive behavioral therapy
KW  - controlled study
KW  - depression
KW  - female
KW  - human
KW  - male
KW  - meta analysis
KW  - quality of life
KW  - randomized controlled trial (topic)
KW  - remission
KW  - social phobia
L1  - internal-pdf://4209784512/Yang-2018-Efficacy and acceptability of psycho.pdf
LA  - English
M3  - In Press
PY  - 2018
SP  - 1-11
T2  - European Child and Adolescent Psychiatry
TI  - Efficacy and acceptability of psychological interventions for social anxiety disorder in children and adolescents: a meta-analysis of randomized controlled trials
UR  - http://www.springerlink.com/content/1018-8827
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=623034228
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1007%2Fs00787-018-1189-x&amp;issn=1018-8827&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-11&amp;date=2018&amp;title=European+Child+and+Adolescent+Psychiatry&amp;atitle=Efficacy+and+acceptability+of+psychological+interventions+for+social+anxiety+disorder+in+children+and+adolescents%3A+a+meta-analysis+of+randomized+controlled+trials&amp;aulast=Yang&amp;pid=%3Cauthor%3EYang+L.%3C%2Fauthor%3E%3CAN%3E623034228%3C%2FAN%3E%3CDT%3EArticle+In+Press%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs00787-018-1189-x
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Pediatric chronic pain is relatively common in the world. Although cognitive behavior therapy (CBT) has been shown to be efficacious in children and adolescents, it is generally recognized that availability and accessibility of CBT are limited. While Internet-delivered cognitive-behavioral therapy (ICBT) performs better in these areas.

**OBJECTIVES: **
This systematic review aims to evaluate the clinical effects of ICBT for chronic pain in youth when compared with the control treatments.

**METHODS: **
We searched electronic databases to identify randomized controlled trials that compared ICBT with the control therapy for pediatric chronic pain. The primary outcomes were 95% confidence intervals and mean difference or standardized mean difference in change of pain intensity and activity limitations.

**RESULTS: **
Four trials met the inclusion criteria with a total of 404 participants of whom 208 received ICBT. Compared with pretreatment, children reported significant, medium to large benefits on pain intensity, activity limitations, and parental protective behaviors after receiving ICBT immediately. Significant small to medium effects were found for outcomes of depressive symptoms, anxiety, and sleep quality from baseline to post-treatment in the ICBT group. But most measures of ICBT did not show statistically significant superiority to those of the control conditions, except parental protective behaviors. Generally children and their parents were highly acceptable and satisfied with ICBT.

**CONCLUSION: **
ICBT for physical and psychological conditions in youth with chronic pain is a full potential therapy; it can be successful on clinically effects and socioeconomic benefits. However, only limited data supported the conclusion, we require further methodologically robust trials.

Systematic review registration: Prospero crd42017069811.
AD  - Tang, Wen-Xin. Department of Anaesthesiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
AN  - 30200086
AU  - Tang,
AU  - W.
AU  - X.
AU  - Zhang,
AU  - L.
AU  - F.
AU  - Ai,
AU  - Y.
AU  - Q.
AU  - Li,
AU  - Z.
AU  - S.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/MD.0000000000012061
DP  - Ovid Technologies
J2  - Medicine (Baltimore)
KW  - Adolescent
KW  - Child
KW  - *Chronic Pain/th [Therapy]
KW  - *Cognitive Therapy
KW  - Humans
KW  - *Internet
KW  - Pain Management/mt [Methods]
KW  - *Pain Management
KW  - Randomized Controlled Trials as Topic
KW  - *Therapy, Computer-Assisted
L1  - internal-pdf://3822792917/Tang-2018-Efficacy of Internet-delivered cogni.pdf
LA  - English
M3  - Meta-Analysis
Review
N1  - Tang, Wen-XinZhang, Lu-FengAi, Yan-QiuLi, Zhi-Song
PY  - 2018
SP  - e12061
T2  - Medicine
TI  - Efficacy of Internet-delivered cognitive-behavioral therapy for the management of chronic pain in children and adolescents: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=30200086
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30200086&amp;id=doi:10.1097%2FMD.0000000000012061&amp;issn=0025-7974&amp;isbn=&amp;volume=97&amp;issue=36&amp;spage=e12061&amp;pages=e12061&amp;date=2018&amp;title=Medicine&amp;atitle=Efficacy+of+Internet-delivered+cognitive-behavioral+therapy+for+the+management+of+chronic+pain+in+children+and+adolescents%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Tang&amp;pid=%3Cauthor%3ETang+WX%3C%2Fauthor%3E%3CAN%3E30200086%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133396/pdf/medi-97-e12061.pdf
VL  - 97
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
The rising prevalence of autism spectrum disorders (ASD) increases the need for evidence-based behavioral treatments to lessen the impact of symptoms on children&#039;s functioning. At present, there are no curative or psychopharmacological therapies to effectively treat all symptoms of the disorders. Early intensive behavioral intervention (EIBI) is a treatment based on the principles of applied behavior analysis. Delivered for multiple years at an intensity of 20 to 40 hours per week, it is one of the more well-established treatments for ASD. This is an update of a Cochrane review last published in 2012.

**OBJECTIVES:**
To systematically review the evidence for the effectiveness of EIBI in increasing functional behaviors and skills, decreasing autism severity, and improving intelligence and communication skills for young children with ASD.

**SEARCH METHODS:**
We searched CENTRAL, MEDLINE, Embase, 12 additional electronic databases and two trials registers in August 2017. We also checked references and contacted study authors to identify additional studies.

**SELECTION CRITERIA:**
Randomized control trials (RCTs), quasi-RCTs, and controlled clinical trials (CCTs) in which EIBI was compared to a no-treatment or treatment-as-usual control condition. Participants must have been less than six years of age at treatment onset and assigned to their study condition prior to commencing treatment.

**DATA COLLECTION AND ANALYSIS:**
We used standard methodological procedures expected by Cochrane.We synthesized the results of the five studies using a random-effects model of meta-analysis, with a mean difference (MD) effect size for outcomes assessed on identical scales, and a standardized mean difference (SMD) effect size (Hedges&#039; g) with small sample correction for outcomes measured on different scales. We rated the quality of the evidence using the GRADE approach.MAIN 

**RESULTS:**
We included five studies (one RCT and four CCTs) with a total of 219 children: 116 children in the EIBI groups and 103 children in the generic, special education services groups. The age of the children ranged between 30.2 months and 42.5 months. Three of the five studies were conducted in the USA and two in the UK, with a treatment duration of 24 months to 36 months. All studies used a treatment-as-usual comparison group.Primary outcomesThere is low quality-evidence at post-treatment that EIBI improves adaptive behaviour (MD 9.58 (assessed using Vineland Adaptive Behavior Scale (VABS) Composite; normative mean = 100, normative SD = 15), 95% confidence interval (CI) 5.57 to 13.60, P &lt; 0.0001; 5 studies, 202 participants), and reduces autism symptom severity (SMD -0.34, 95% CI -0.79 to 0.11, P = 0.14; 2 studies, 81 participants; lower values indicate positive effects) compared to treatment as usual.No adverse effects were reported across studies.Secondary outcomesThere is low-quality evidence at post-treatment that EIBI improves IQ (MD 15.44 (assessed using standardized IQ tests; scale 0 to 100, normative SD = 15), 95% CI 9.29 to 21.59, P &lt; 0.001; 5 studies, 202 participants); expressive (SMD 0.51, 95% CI 0.12 to 0.90, P = 0.01; 4 studies, 165 participants) and receptive (SMD 0.55, 95% CI 0.23 to 0.87, P = 0.001; 4 studies, 164 participants) language skills; and problem behaviour (SMD -0.58, 95% CI -1.24 to 0.07, P = 0.08; 2 studies, 67 participants) compared to treatment as usual.

**AUTHORS&#039; CONCLUSIONS:**
There is weak evidence that EIBI may be an effective behavioral treatment for some children with ASD; the strength of the evidence in this review is limited because it mostly comes from small studies that are not of the optimum design. Due to the inclusion of non-randomized studies, there is a high risk of bias and we rated the overall quality of evidence as &#039;low&#039; or &#039;very low&#039; using the GRADE system, meaning further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate.It is important that providers of EIBI are aware of the current evidence and use clinical decision-making guidelines, such as seeking the family&#039;s input and drawing upon prior clinical experience, when making recommendations to clients on the use EIBI. Additional studies using rigorous research designs are needed to make stronger conclusions about the effects of EIBI for children with ASD.
AU  - Reichow,
AU  - B.
AU  - Hume,
AU  - K.
AU  - Barton,
AU  - E.
AU  - E.
AU  - Boyd,
AU  - B.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009260.pub3_
L1  - internal-pdf://3889371078/Reichow_et_al-2018-Cochrane_Database_of_System.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Early intensive behavioral intervention (EIBI) for young children with autism spectrum disorders (ASD)
ER  -
TY  - JOUR
AB  - **IMPORTANCE **
Unhealthy alcohol use is common, increasing, and a leading cause of premature mortality. 

**OBJECTIVE **
To review literature on the effectiveness and harms of screening and counseling for unhealthy alcohol use to inform the US Preventive Services Task Force. 

**DATA SOURCES **
MEDLINE, PubMed, PsycINFO, and the Cochrane Central Register of Controlled Trials through October 12, 2017; literature surveillance through August 1, 2018. 

**STUDY SELECTION **
Test accuracy studies and randomized clinical trials of screening and counseling to reduce unhealthy alcohol use. 

**DATA EXTRACTION AND SYNTHESIS **
Independent critical appraisal and data abstraction by 2 reviewers. Counseling trials were pooled using random-effects meta-analyses. 

**MAIN OUTCOMES AND MEASURES **
Sensitivity, specificity, drinks perweek, exceeding recommended limits, heavy use episodes, abstinence (for pregnant women), and other health, family, social, and legal outcomes. 

**RESULTS **
One hundred thirteen studies (N = 314 466) were included. No studies examined benefits or harms of screening programs to reduce unhealthy alcohol use. For adolescents (10 studies [n = 171 363]), 1 study (n = 225) reported a sensitivity of 0.73 (95% CI, 0.60 to 0.83) and specificity of 0.81 (95% CI, 0.74 to 0.86) using the AUDIT-C (Alcohol Use Disorders Identification Test-Consumption) to detect the full spectrum of unhealthy alcohol use. For adults (35 studies [n = 114 182]), brief screening instruments commonly reported sensitivity and specificity between 0.70 and 0.85. Two trials of the effects of interventions to reduce unhealthy alcohol use in adolescents (n = 588) found mixed results: one reported a benefit in high-risk but not moderate-risk drinkers, and the other reported a statistically significant reduction in drinking frequency for boys but not girls; neither reported health or related outcomes. Across all populations (68 studies [n = 36 528]), counseling interventions were associated with a decrease in drinks per week (weighted mean difference, -1.6 [95% CI, -2.2 to -1.0]; 32 studies [37 effects; n = 15 974]), the proportion exceeding recommended drinking limits (odds ratio [OR], 0.60 [95% CI, 0.53 to 0.67]; 15 studies [16 effects; n = 9760]), and the proportion reporting a heavy use episode (OR, 0.67 [95% CI, 0.58 to 0.77]; 12 studies [14 effects; n = 8108]), and an increase in the proportion of pregnant women reporting abstinence (OR, 2.26 [95% CI, 1.43 to 3.56]; 5 studies [n = 796]) after 6 to 12 months. Health outcomes were sparsely reported and generally did not demonstrate group differences in effect. There was no evidence that these interventions could be harmful. 

**CONCLUSIONS AND RELEVANCE **
Among adults, screening instruments feasible for use in primary care are available that can effectively identify people with unhealthy alcohol use, and counseling interventions in those who screen positive are associated with reductions in unhealthy alcohol use. There was no evidence that these interventions have unintended harmful effects.
AD  - [O&#039;Connor, Elizabeth A.; Perdue, Leslie A.; Senger, Caitlyn A.; Rushkin, Megan; Patnode, Carrie D.; Bean, Sarah I.] Kaiser Permanente, Ctr Hlth Res, Kaiser Permanente Res Affiliates Evidence Based P, Portland, OR USA. [Jonas, Daniel E.] Univ N Carolina, Chapel Hill, NC 27515 USA.O&#039;Connor, EA (reprint author), Kaiser Permanente Northwest, Kaiser Permanente Res Affiliates Evidence Based P, Ctr Hlth Res, 3800 N Interstate Ave, Portland, OR 97227 USA.elizabethoconnor@kpchr.org
AN  - WOS:000449945900018
AU  - O&#039;Connor,
AU  - E.
AU  - A.
AU  - Perdue,
AU  - L.
AU  - A.
AU  - Senger,
AU  - C.
AU  - A.
AU  - Rushkin,
AU  - M.
AU  - Patnode,
AU  - C.
AU  - D.
AU  - Bean,
AU  - S.
AU  - I.
AU  - Jonas,
AU  - D.
AU  - E.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1001/jama.2018.12086
J2  - JAMA-J. Am. Med. Assoc.
KW  - randomized controlled-trial
KW  - disorders identification test
KW  - at-risk
KW  - drinking
KW  - brief physician advice
KW  - personalized normative feedback
KW  - primary-care patients
KW  - detecting hazardous drinkers
KW  - 1st-year
KW  - college-students
KW  - general-practice patients
KW  - sexual health clinics
KW  - General &amp; Internal Medicine
L1  - internal-pdf://2501545022/O&#039;Connor-2018-Screening and Behavioral Counsel.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: HA1BHTimes Cited: 2Cited Reference Count: 178O&#039;Connor, Elizabeth A. Perdue, Leslie A. Senger, Caitlyn A. Rushkin, Megan Patnode, Carrie D. Bean, Sarah I. Jonas, Daniel E.Agency for Healthcare Research and Quality (AHRQ), US Department of Health and Human Services [HHSA-290-2015-000017-I-EPC5]This research was funded under contract HHSA-290-2015-000017-I-EPC5, Task Order No. 2 from the Agency for Healthcare Research and Quality (AHRQ), US Department of Health and Human Services, under a contract to support the USPSTF.20Amer medical assocChicago1538-3598
PY  - 2018
SP  - 1910-1928
T2  - Jama-Journal of the American Medical Association
TI  - Screening and Behavioral Counseling Interventions to Reduce Unhealthy Alcohol Use in Adolescents and Adults Updated Evidence Report and Systematic Review for the US Preventive Services Task Force
UR  - &lt;Go to ISI&gt;://WOS:000449945900018
UR  - https://jamanetwork.com/journals/jama/articlepdf/2714536/jama_oconnor_2018_us_180021.pdf
VL  - 320
ER  -
TY  - JOUR
AB  - This is the first meta-meta-analysis examining the effects of parent-based interventions for children with externalizing behavior problems on parental characteristics (parenting, parental perceptions, parental mental health, parental relationship quality). Parent training interventions are recognized as evidence-based interventions for the treatment of externalizing behavior problems, although meta-analytic effects are heterogeneous. 

The objective of the present study was to comprehensively combine meta-analytic results on parent training interventions to arrive at valid effect predictions. Electronic databases were searched (PsycINFO, Medline, PubMed). In total, 11 meta-analyses were included that mainly comprised parents of children under the age of 13 years. 

Analyses were based on random effects models. Effect estimates were transformed to standardized mean differences (SMD) and corrected for primary study overlap. Results revealed a significant moderate overall effect for parenting (SMD 0.53) as well as for parents&#039; report of parenting (SMD 0.60) and parental perceptions (SMD 0.52). Effects remained stable to follow-up. Results for observational data, parental mental health and parental relationship quality were small and only partially significant. Considerable heterogeneity within results was revealed. 

Overall, parent training interventions proved to be effective in improving parental characteristics for parents of children with externalizing behavior problems. Effectiveness was stronger regarding characteristics explicitly targeted by interventions. The findings should encourage health-care providers to apply evidence-based parent training interventions. Copyright &copy; 2018 Springer-Verlag GmbH Germany, part of Springer Nature
AD  - (Weber, Kamp-Becker, Mingebach) Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Hans-Sachs-Strabetae 4, Marburg 35039, Germany (Christiansen) Department of Clinical Child and Adolescent Psychology, Philipps University Marburg, Marburg, GermanyL. Weber, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Hans-Sachs-Strabetae 4, Marburg 35039, Germany. E-mail: linda.weber@med.uni-marburg.de
AN  - 622525438
AU  - Weber,
AU  - L.
AU  - Kamp-Becker,
AU  - I.
AU  - Christiansen,
AU  - H.
AU  - Mingebach,
AU  - T.
DA  - 08 Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00787-018-1175-3
DP  - Ovid Technologies
KW  - Externalizing behavior problems
KW  - Meta-meta-analysis
KW  - Parent training effectiveness
KW  - Parents
KW  - adolescent
KW  - article
KW  - child
KW  - child parent relation
KW  - female
KW  - follow up
KW  - health care personnel
KW  - human
KW  - male
KW  - Medline
KW  - mental health
KW  - meta analysis
KW  - perception
KW  - prediction
KW  - problem behavior
KW  - PsycINFO
KW  - systematic review
L1  - internal-pdf://3734326082/Weber-2018-Treatment of child externalizing be.pdf
LA  - English
M3  - In Press
PY  - 2018
SP  - 1-12
T2  - European Child and Adolescent Psychiatry
TI  - Treatment of child externalizing behavior problems: a comprehensive review and meta-meta-analysis on effects of parent-based interventions on parental characteristics
UR  - http://www.springerlink.com/content/1018-8827
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=622525438
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1007%2Fs00787-018-1175-3&amp;issn=1018-8827&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-12&amp;date=2018&amp;title=European+Child+and+Adolescent+Psychiatry&amp;atitle=Treatment+of+child+externalizing+behavior+problems%3A+a+comprehensive+review+and+meta-meta-analysis+on+effects+of+parent-based+interventions+on+parental+characteristics&amp;aulast=Weber&amp;pid=%3Cauthor%3EWeber+L.%3C%2Fauthor%3E%3CAN%3E622525438%3C%2FAN%3E%3CDT%3EArticle+In+Press%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs00787-018-1175-3
ER  -
TY  - JOUR
AB  - Adopted children and adolescents are at an increased risk of experiencing emotional, behavioural and relational difficulties compared to their non-adopted peers. This systematic review aimed to establish the effectiveness of interventions with adoptive parents on adopted children and adolescents&#039; psychological well-being, behavioural functioning and parent-child relationship. 

A systematic search was performed adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA), including studies that assessed the effects of interventions with adoptive parents on adopted child and adolescent outcomes. Electronic databases, key journals, grey literature sources, reference and citation lists were searched and published authors in the field were contacted; 19 papers describing 15 interventions were included. 

The findings from this review provide preliminary support for the use of interventions with adoptive parents for improving adopted children&#039;s emotional and behavioural outcomes. However, overall, the studies were found to have a high risk of bias, and the significant heterogeneity across the studies limits the conclusions that can be drawn. Further research is required to provide conclusive recommendations regarding the effectiveness of interventions with adoptive parents on the outcomes of adopted children.
AD  - Ni Chobhthaigh, Sorcha. School of Health in Social Science, The University of Edinburgh, Scotland.Duffy, Fiona. School of Health in Social Science, The University of Edinburgh, Scotland.
AN  - 29998743
AU  - Ni
AU  - Chobhthaigh,
AU  - S.
AU  - Duffy,
AU  - F.
DA  - Jul 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1359104518786339
DP  - Ovid Technologies
J2  - Clin
L1  - internal-pdf://1098980966/Ni Chobhthaigh-2018-The effectiveness of psych.pdf
LA  - English
N1  - Ni Chobhthaigh, SorchaDuffy, Fiona
PY  - 2018
SP  - 1359104518786339
T2  - Clinical Child Psychology &amp; Psychiatry
TI  - The effectiveness of psychological interventions with adoptive parents on adopted children and adolescents&#039; outcomes: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29998743
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29998743&amp;id=doi:10.1177%2F1359104518786339&amp;issn=1359-1045&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1359104518786339&amp;pages=1359104518786339&amp;date=2018&amp;title=Clinical+Child+Psychology+%26+Psychiatry&amp;atitle=The+effectiveness+of+psychological+interventions+with+adoptive+parents+on+adopted+children+and+adolescents%27+outcomes%3A+A+systematic+review.&amp;aulast=Ni+Chobhthaigh&amp;pid=%3Cauthor%3ENi+Chobhthaigh+S%3C%2Fauthor%3E%3CAN%3E29998743%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Objective: **
School refusal is a psychosocial problem associated with adverse short- and long-term consequences for children and adolescents. The authors conducted a systematic review and meta-analysis to examine the effects of psychosocial treatments for children and adolescents with school refusal. 

**Method: **
A comprehensive search process was used to find eligible randomized controlled trials and quasi-experimental studies assessing the effects of psychosocial treatments on anxiety or attendance outcomes. Data were quantitatively synthesized using meta-analytic methods. 

**Results: **
Eight studies including 435 children and adolescents with school refusal were included in this review. Significant effects were found for attendance but not for anxiety. 

**Conclusions: **
Evidence indicates that improvements in school attendance occur for children and adolescents with school refusal who receive psychosocial treatment. The lack of evidence of short-term effects on anxiety points to the need for long-term follow-up studies to determine whether increased attendance ultimately leads to reduced anxiety.
AN  - WOS:000417860300006
AU  - Maynard,
AU  - B.
AU  - R.
AU  - Heyne,
AU  - D.
AU  - Brendel,
AU  - K.
AU  - E.
AU  - Bulanda,
AU  - J.
AU  - J.
AU  - Thompson,
AU  - A.
AU  - M.
AU  - Pigott,
AU  - T.
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1049731515598619
L1  - internal-pdf://2505807357/Maynard-2018-Treatment for School Refusal Amon.pdf
PY  - 2018
SP  - 56-67
T2  - Research on Social Work Practice
TI  - Treatment for School Refusal Among Children and Adolescents: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000417860300006
UR  - http://journals.sagepub.com/doi/10.1177/1049731515598619
UR  - http://journals.sagepub.com/doi/pdf/10.1177/1049731515598619
VL  - 28
ER  -
TY  - JOUR
AB  - Group social skills interventions (GSSIs) are a commonly offered treatment for children with high functioning ASD. We critically evaluated GSSI randomised controlled trials for those aged 6-25 years. 

Our meta-analysis of outcomes emphasised internal validity, thus was restricted to trials that used the parent-report social responsiveness scale (SRS) or the social skills rating system (SSRS). 

Large positive effect sizes were found for the SRS total score, plus the social communication and restricted interests and repetitive behaviours subscales. 

The SSRS social skills subscale improved with moderate effect size. Moderator analysis of the SRS showed that GSSIs that include parent-groups, and are of greater duration or intensity, obtained larger effect sizes. 

We recommend future trials distinguish gains in children&#039;s social knowledge from social performance. 

Copyright &copy; 2018 The Author(s)
AN  - 620623403
AU  - Wolstencroft,
AU  - J.
AU  - Robinson,
AU  - L.
AU  - Srinivasan,
AU  - R.
AU  - Kerry,
AU  - E.
AU  - Mandy,
AU  - W.
AU  - Skuse,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10803-018-3485-1
L1  - internal-pdf://2004936707/Wolstencroft-2018-A Systematic Review of Group.pdf
PY  - 2018
SP  - 1-15
T2  - Journal of Autism and Developmental Disorders
TI  - A Systematic Review of Group Social Skills Interventions, and Meta-analysis of Outcomes, for Children with High Functioning ASD
UR  - http://www.wkap.nl/journalhome.htm/0162-3257
UR  - https://link.springer.com/content/pdf/10.1007%2Fs10803-018-3485-1.pdf
ER  -
TY  - JOUR
AB  - Depression and anxiety are common during adolescence. Whilst effective interventions are available treatment services are limited resulting in many adolescents being unable to access effective help. Delivering mental health interventions via technology, such as computers or the internet, offers one potential way to increase access to psychological treatment. 

The aim of this systematic review and meta-analysis was to update previous work and investigate the current evidence for the effect of technology delivered interventions for children and adolescents (aged up to 18 years) with depression and anxiety. A systematic search of eight electronic databases identified 34 randomized controlled trials involving 3113 children and young people aged 6-18. 

The trials evaluated computerized and internet cognitive behavior therapy programs (CBT: n = 17), computer-delivered attention bias modification programs (ABM: n = 8) cognitive bias modification programs (CBM: n = 3) and other interventions (n = 6). Our results demonstrated a small effect in favor of technology delivered interventions compared to a waiting list control group: g = 0.45 [95% CI 0.29, 0.60] p &lt; 0.001. CBT interventions yielded a medium effect size (n = 17, g = 0.66 [95% CI 0.42-0.90] p &lt; 0.001). 

ABM interventions yielded a small effect size (n = 8, g = 0.41 [95%CI 0.08-0.73] p &lt; 0.01). CBM and &#039;other&#039; interventions failed to demonstrate a significant benefit over control groups. Type of control condition, problem severity, therapeutic support, parental support, and continuation of other ongoing treatment significantly influenced effect sizes. 

Our findings suggest there is a benefit in using CBT based technology delivered interventions where access to traditional psychotherapies is limited or delayed.
AD  - Grist, Rebecca. Department for Health, University of Bath, 6.19 Wessex House, Bath, BA2 7AY, UK. r.grist@brighton.ac.uk.Grist, Rebecca. School of Applied Social Science, University of Brighton, Mayfield House, Falmer, Brighton, BN1 9PH, UK. r.grist@brighton.ac.uk.Croker, Abigail. Oxford Health NHS Foundation Trust, Child, and Adolescent Mental Health Service, Temple House, Keynsham, UK.Denne, Megan. Oxford Health NHS Foundation Trust, Child, and Adolescent Mental Health Service, Temple House, Keynsham, UK.Stallard, Paul. Department for Health, University of Bath, 6.19 Wessex House, Bath, BA2 7AY, UK.Stallard, Paul. Oxford Health NHS Foundation Trust, Child, and Adolescent Mental Health Service, Temple House, Keynsham, UK.
AN  - 30229343
AU  - Grist,
AU  - R.
AU  - Croker,
AU  - A.
AU  - Denne,
AU  - M.
AU  - Stallard,
AU  - P.
DA  - Sep 18
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-018-0271-8
DP  - Ovid Technologies
J2  - Clin Child Fam Psychol Rev
L1  - internal-pdf://1338575504/Grist-2018-Technology Delivered Interventions.pdf
LA  - English
M3  - Review
N1  - Using Smart Source ParsingSepGrist, RebeccaCroker, AbigailDenne, MeganStallard, Paul
PY  - 2018
SP  - 18
T2  - Clinical Child &amp; Family Psychology Review
TI  - Technology Delivered Interventions for Depression and Anxiety in Children and Adolescents: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=30229343
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30229343&amp;id=doi:10.1007%2Fs10567-018-0271-8&amp;issn=1096-4037&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2018&amp;title=Clinical+Child+%26+Family+Psychology+Review&amp;atitle=Technology+Delivered+Interventions+for+Depression+and+Anxiety+in+Children+and+Adolescents%3A+A+Systematic+Review+and+Meta-analysis.&amp;aulast=Grist&amp;pid=%3Cauthor%3EGrist+R%3C%2Fauthor%3E%3CAN%3E30229343%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/content/pdf/10.1007%2Fs10567-018-0271-8.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering for effektene av Kjærlighet og Grenser i Norden. Artikkelen bygger på en tidligere beskrivelse av det samme tiltaket i Ungsinn (Bjørknes, 2011) men er videreutviklet i henhold til Ungsinn sine nye kriterier og med et oppdatert litteratursøk. Kjærlig-het og Grenser er ment å være et rusforebyggende program rettet mot unge i alderen 10-14 år og deres foreldre. Kompetansesenter rus &ndash; region sør (KoRus Sør) har det nasjonale ansvaret for å ut-vikle og gi opplæring i programmet. Programmet er opprinnelig utviklet i USA (Iowa Strengthening Families Program), videreutviklet i Sverige (ParentSteps, Step-by-Step) og implementert i Norge fra 2004.

METODE
Det ble gjort litteratursøk i databasene Embase, Medline og Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS og SweMed. Søket resulterte i to svenske effektstudier som ble inkludert.

RESULTATER
Resultatene omfatter en beskrivelse av tiltaket samt en oppsummering av effektstudier, forsknings-metodisk kvalitet og implementeringskvalitet. Kjærlighet og Grenser er godt beskrevet i flere doku-menter blant annet gjennom en detaljert manual. Tiltaket har tilfredstillende systemer for å sikre implementeringskvalitet. Det foreligger to studier fra Sverige som undersøker effekten av tiltaket. Begge studiene benytter randomiserte design med kontrollgrupper, målinger ved oppstart og se-nere oppfølging. Studiene er av god forskningsmetodisk kvalitet. Det er ikke funnet signifikante ef-fekter på relevante utfallsmål, slik som unges rus- eller atferdsproblemer.

KONKLUSJON
Basert på Ungsinn sine kriterier klassifiseres Kjærlighet og Grenser på evidensnivå 0 &ndash; uvirksomt tiltak. Studiene som er gjennomført i Sverige er av god forskningsmetodisk kvalitet og viser at tiltaket ikke har effekt.
AU  - Bjørknes,
AU  - R.,
AU  - Koposov,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2018
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Kjærlighet og grenser (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/kjaerlighet-og-grenser-2-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
This review is an updated version of the original Cochrane review published in Issue 4, 2006. Needle-related procedures are a common source of pain and distress for children. Our previous review on this topic indicated that a number of psychological interventions were efficacious in managing pediatric needle pain, including distraction, hypnosis, and combined cognitive behavioural interventions. Considerable additional research in the area has been published since that time.

**OBJECTIVES:**
To provide an update to our 2006 review assessing the efficacy of psychological interventions for needle-related procedural pain and distress in children and adolescents.

**SEARCH METHODS:**
Searches of the following databases were conducted for relevant randomized controlled trials (RCTs): Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE; EMBASE; PsycINFO; the Cumulative Index to Nursing and Allied Health Literature (CINAHL); and Web of Science. Requests for relevant studies were also posted on various electronic list servers. We ran an updated search in March 2012, and again in March 2013.

**SELECTION CRITERIA:**
Participants included children and adolescents aged two to 19 years undergoing needle-related procedures. Only RCTs with at least five participants in each study arm comparing a psychological intervention group with a control or comparison group were eligible for inclusion.

**DATA COLLECTION AND ANALYSIS:**
Two review authors extracted data and assessed trial quality and a third author helped with data extraction and coding for one non-English study. Included studies were coded for quality using the Cochrane Risk of bias tool. Standardized mean differences with 95% confidence intervals were computed for all analyses using Review Manager 5.2 software.

**MAIN RESULTS:**
Thirty-nine trials with 3394 participants were included. The most commonly studied needle procedures were venipuncture, intravenous (IV) line insertion, and immunization. Studies included children aged two to 19 years, with the most evidence available for children under 12 years of age. Consistent with the original review, the most commonly studied psychological interventions for needle procedures were distraction, hypnosis, and cognitive behavioural therapy (CBT). The majority of included studies (19 of 39) examined distraction only. The additional studies from this review update continued to provide strong evidence for the efficacy of distraction and hypnosis. No evidence was available to support the efficacy of preparation and information, combined CBT (at least two or more cognitive or behavioural strategies combined), parent coaching plus distraction, suggestion, or virtual reality for reducing children&#039;s pain and distress. No conclusions could be drawn about interventions of memory alteration, parent positioning plus distraction, blowing out air, or distraction plus suggestion, as evidence was available from single studies only. In addition, the Risk of bias scores indicated several domains with high or unclear bias scores (for example, selection, detection, and performance bias) suggesting that the methodological rigour and reporting of RCTs of psychological interventions continue to have considerable room for improvement.

**AUTHORS&#039; CONCLUSIONS:**
Overall, there is strong evidence supporting the efficacy of distraction and hypnosis for needle-related pain and distress in children and adolescents, with no evidence currently available for preparation and information or both, combined CBT, parent coaching plus distraction, suggestion, or virtual reality. Additional research is needed to further assess interventions that have only been investigated in one RCT to date (that is, memory alteration, parent positioning plus distraction, blowing out air, and distraction plus suggestion). There are continuing issues with the quality of trials examining psychological interventions for needle-related pain and distress.

Update of
Psychological interventions for needle-related procedural pain and distress in children and adolescents. [Cochrane Database Syst Rev. 2006]
AU  - Birnie,
AU  - K.
AU  - A.
AU  - Noel,
AU  - M.
AU  - Chambers,
AU  - C.
AU  - T.
AU  - Uman,
AU  - L.
AU  - S.
AU  - Parker,
AU  - J.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
L1  - internal-pdf://3965958772/Birnie-2018-Psychological interventions for ne.pdf
PY  - 2018
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological interventions for needle‐related procedural pain and distress in children and adolescents (Update)
ER  -
TY  - JOUR
AB  - **Background: **
Every year, more than 800,000 people worldwide die by suicide. The aim of this study was to conduct a systematic review of the effectiveness of brief psychological interventions in addressing suicidal thoughts and behaviour in healthcare settings. 

**Methods:**
Following PRISMA guidelines, systematic searches were conducted in MEDLINE, CINAHL, EMBASE, the Cochrane Central Register of Controlled Trials and PsycINFO databases. A predefined search strategy was used. Two independent reviewers screened titles and abstracts followed by full texts against predefined inclusion criteria. Backward and forward citation tracking of included papers was conducted. Quality appraisal was conducted using the Cochrane Risk of Bias Tool for Randomized Controlled Trials and the CASP tool for randomised controlled trials. The small number and heterogeneity of studies did not allow for meta-analysis to be conducted. A narrative synthesis was conducted. 

**Results:**
Four controlled studies of brief psychological interventions were included, conducted in Switzerland, the U.S. and across low and middle-income countries. Three studies were conducted with adults and one with adolescents. All studies were judged to be at low risk of bias. All of the interventions were implemented with patients after attending emergency departments and involved 3412 participants. The main outcomes were suicide, suicide attempts, suicidal ideation, depression and hospitalization. The components of the interventions were early therapeutic engagement, information provision, safety planning and follow-up contact for at least 12 months. The interventions drew to, different degrees, on psychological theory and techniques. Two trials that measured suicidal ideation found no impact. Two studies showed fewer suicide attempts, one showed fewer suicides and one found an effect on depression. 

**Conclusions:** 
Although the evidence base is small, brief psychological interventions appear to be effective in reducing suicide and suicide attempts. All studies to date have been conducted with people who had attended the ED but the interventions could potentially be adopted for inpatient and other outpatient settings. Early engagement and therapeutic intervention based on psychological theories of suicidal behaviour, sustained in follow-up contacts, may be particularly beneficial. 

Copyright &copy; 2018 The Author(s).
AD  - (McCabe, Backhouse, Xanthopoulou) University of Exeter Medical School, Heavitree Road, Exeter EX1 2LU, United Kingdom (Garside) Royal Cornwall Hospital, European Centre for Environment and Human Health, Knowledge Spa, Truro TR1 3HD, United KingdomP. Xanthopoulou, University of Exeter Medical School, Heavitree Road, Exeter EX1 2LU, United Kingdom. E-mail: p.d.xanthopoulou@exeter.ac.uk
AN  - 621965379
AU  - McCabe,
AU  - R.
AU  - Garside,
AU  - R.
AU  - Backhouse,
AU  - A.
AU  - Xanthopoulou,
AU  - P.
DA  - 03 May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s12888-018-1663-5
DP  - Ovid Technologies
KW  - Controlled studies
KW  - Effective communication
KW  - Suicidal ideation
KW  - Suicide
KW  - Systematic review
KW  - alcohol consumption
KW  - article
KW  - clinical effectiveness
KW  - clinical evaluation
KW  - depression
KW  - follow up
KW  - health care utilization
KW  - hopelessness
KW  - hospitalization
KW  - human
KW  - low income country
KW  - middle income country
KW  - outcome assessment
KW  - psychotherapy
KW  - risk assessment
KW  - suicidal ideation/th [Therapy]
KW  - suicide attempt/th [Therapy]
KW  - Switzerland
KW  - therapy effect
L1  - internal-pdf://3284143769/McCabe-2018-Effectiveness of brief psychologic.pdf
LA  - English
PY  - 2018
T2  - BMC Psychiatry
TI  - Effectiveness of brief psychological interventions for suicidal presentations: A systematic review
UR  - http://www.biomedcentral.com/bmcpsychiatr/
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=621965379
UR  - https://bmcpsychiatry.biomedcentral.com/track/pdf/10.1186/s12888-018-1663-5
VL  - 18 (1) (no pagination)
ER  -
TY  - JOUR
AB  - **Aim: **
To systematically review and meta-analyse studies of neurodevelopmental outcome of children born to mothers prescribed methadone in pregnancy. 

**Method(s): **
MEDLINE, Embase, and PsycINFO were searched for studies published from 1975 to 2017 reporting neurodevelopmental outcomes in children with prenatal methadone exposure. 

**Result(s): **
Forty-one studies were identified (2283 participants). Eight studies were amenable to meta-analysis: at 2 years the Mental Development Index weighted mean difference of children with prenatal methadone exposure compared with unexposed infants was -4.3 (95% confidence interval [CI] -7.24 to -1.63), and the Psychomotor Development Index weighted mean difference was -5.42 (95% CI -10.55 to -0.28). Seven studies reported behavioural scores and six found scores to be lower among methadone-exposed children. Twelve studies reported visual outcomes: nystagmus and strabismus were common; five studies reported visual evoked potentials of which four described abnormalities. Factors that limited the quality of some studies, and introduced risk of bias, included absence of blinding, small sample size, high attrition, uncertainty about polydrug exposure, and lack of comparison group validity. 

**Interpretation(s): **
Children born to mothers prescribed methadone in pregnancy are at risk of neurodevelopmental problems but risk of bias limits inference about harm. Research into management of opioid use disorder in pregnancy should include evaluation of childhood neurodevelopmental outcome. 

**What this Study Adds: **
Children born to opioid-dependent mothers prescribed methadone are at risk of neurodevelopmental impairment. Exposed infants have lower Mental Development Index and Psychomotor Development Index scores than unexposed children. Atypical visual evoked potentials, strabismus, and nystagmus have increased prevalence. Estimates of impairment may be biased by intermediate to poor quality evidence.

Copyright &copy; 2018 The Authors. Developmental Medicine &amp; Child Neurology published by John Wiley &amp; Sons Ltd on behalf of Mac Keith Press
AN  - 625382513
AU  - Monnelly,
AU  - V.
AU  - J.
AU  - Hamilton,
AU  - R.
AU  - Chappell,
AU  - F.
AU  - M.
AU  - Mactier,
AU  - H.
AU  - Boardman,
AU  - J.
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/dmcn.14117
L1  - internal-pdf://2160397283/Monnelly-2018-Childhood neurodevelopment after.pdf
PY  - 2018
T2  - Developmental Medicine and Child Neurology.
TI  - Childhood neurodevelopment after prescription of maintenance methadone for opioid dependency in pregnancy: a systematic review and meta-analysis
UR  - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1469-8749
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/dmcn.14117
ER  -
TY  - JOUR
AB  - Recent studies have suggested oxytocin as a possible drug to treat social deficits caused by autism spectrum disorder (ASD), but the safety of intranasal oxytocin in autistic patients has not been established. 

The aim of this review was to characterize the side-effect profile of long-term intranasal oxytocin in treatment of ASD compared to placebo. All randomized controlled trials of intranasal oxytocin in the treatment of ASD published before 1 January 2017 that reported safety data were identified from databases, including PubMed, Embase, Cochrane Library, and International Pharmaceutical Abstract. Relevant data from the selected studies were then extracted for met-analysis to estimate the pooled risk ratio for the most common adverse events. 

Descriptive analysis of severe adverse events was also conducted. Of the 223 participants in the five included studies, 123 were given oxytocin and 100 were given placebos. Nasal discomfort (14.3%), tiredness (7.2%), irritability (9.0%), diarrhea (4.5%), and skin irritation (4.5%) were the most common adverse events. None of these common adverse events was statistically associated with treatment allocation according to met-analysis using pooled data (all P-values &gt; 0.1). 

Five severe adverse events were reported, namely aggression (one in placebo, two in oxytocin) and seizures (one in placebo, one in oxytocin). Results from this systematic review support intranasal oxytocin as well tolerated and safe for use in the ASD population. Larger clinical trials should be conducted to establish the efficacy of intranasal oxytocin as a treatment of ASD.
AN  - WOS:000426795500002
AU  - Cai,
AU  - Q.
AU  - Z.
AU  - Feng,
AU  - L.
AU  - Yap,
AU  - K.
AU  - Z.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/pcn.12627
L1  - internal-pdf://3357735022/Cai-2018-Systematic review and meta-analysis o.pdf
PY  - 2018
SP  - 140-151
T2  - Psychiatry and Clinical Neurosciences
TI  - Systematic review and meta-analysis of reported adverse events of long-term intranasal oxytocin treatment for autism spectrum disorder
UR  - &lt;Go to ISI&gt;://WOS:000426795500002
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/pcn.12627
VL  - 72
ER  -
TY  - JOUR
AB  - Sleep disturbance is common among young people, with consequences for academic, emotional and behavioural development. 

Cognitive-behavioural therapy for insomnia (CBT-I) is efficacious, yet it is costly and not available to many who need it. Digitally-delivered CBT-I (eCBT-I) has the potential to overcome these barriers. 

The purpose of this systematic review was to identify studies which report on the efficacy or effectiveness of eCBT-I for young people with sleep disturbance. Electronic databases were systematically searched and three studies met inclusion criteria. 

Two studies used the same online intervention for adolescents with insomnia symptoms, while the other was conducted in a college sample of individuals who opted into a stress-management study. 

Results showed that eCBT-I improved sleep efficiency, sleep quality, sleep-onset latency and total sleep time with effect sizes ranging from 0.17-1.30 (Cohen&#039;s d). This suggests that eCBT-I is a promising intervention for young people, but more studies are needed to verify the conditions under which it is most effective. 

Copyright &copy; 2018 The Authors
AN  - 620618859
AU  - Werner-Seidler,
AU  - A.
AU  - Johnston,
AU  - L.
AU  - Christensen,
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.invent.2018.01.007
L1  - internal-pdf://3450595581/Werner-Seidler_2018.pdf
PY  - 2018
SP  - 71-78
T2  - Internet Interventions
TI  - Digitally-delivered cognitive-behavioural therapy for youth insomnia: A systematic review
UR  - http://www.journals.elsevier.com/internet-interventions/
UR  - https://www.sciencedirect.com/science/article/pii/S2214782917301070?via%3Dihub
VL  - 11
ER  -
TY  - JOUR
AB  - The aim of this meta-analysis was to systematically examine the short- and long-term effects of group Cognitive Behavioral Therapy (CBT) for adolescent depression and to examine the role of various moderators of the reported effect sizes. 

A comprehensive literature search of relevant randomized-controlled trials identified 23 studies containing 49 post-intervention and 56 follow-up comparisons. Standardized mean differences (SMD) were calculated both for post-intervention and follow-up. A three-level random effects approach was used to model the dependent effect sizes. Group CBT was more efficacious than control conditions both at post-intervention (SMD = -0.28, 95% CI [-0.36, -0.19]) and at follow-up (SMD = -0.21, 95% CI [-0.30, -0.11]). 

Having an inactive control group was associated with a larger post-intervention effect size, while having a longer follow-up duration was associated with a smaller follow-up effect size. Even though the effect sizes are low, research suggests that group CBT is a significant treatment for adolescent depression. 

Copyright &copy; 2018 The Foundation for Professionals in Services for Adolescents
AD  - (Keles, Idsoe) Norwegian Center for Child Behavioral Development, NorwayS. Keles, Norwegian Center for Child Behavioral Development, Department of Research, PO. Box 7053, Majorstuen, Oslo 0306, Norway. E-mail: serap.keles@nubu.no
AN  - 2000885203
AU  - Keles,
AU  - S.
AU  - Idsoe,
AU  - T.
DA  - August
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.adolescence.2018.05.011
DP  - Ovid Technologies
KW  - Adolescents
KW  - Depression
KW  - Group CBT
KW  - Meta-analysis
KW  - Randomized control trials
KW  - adolescent
KW  - age
KW  - clinical effectiveness
KW  - cognitive behavioral therapy
KW  - depression/su [Surgery]
KW  - follow up
KW  - gender
KW  - group therapy
KW  - human
KW  - meta analysis
KW  - randomized controlled trial (topic)
KW  - review
KW  - treatment duration
L1  - internal-pdf://1953238632/Keles-2018-A meta-analysis of group Cognitive.pdf
LA  - English
M3  - Review
PY  - 2018
SP  - 129-139
T2  - Journal of Adolescence
TI  - A meta-analysis of group Cognitive Behavioral Therapy (CBT) interventions for adolescents with depression
UR  - http://www.elsevier.com/inca/publications/store/6/2/2/8/4/9/index.htt
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexa&amp;AN=2000885203
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.adolescence.2018.05.011&amp;issn=0140-1971&amp;isbn=&amp;volume=67&amp;issue=&amp;spage=129&amp;pages=129-139&amp;date=2018&amp;title=Journal+of+Adolescence&amp;atitle=A+meta-analysis+of+group+Cognitive+Behavioral+Therapy+%28CBT%29+interventions+for+adolescents+with+depression&amp;aulast=Keles&amp;pid=%3Cauthor%3EKeles+S.%3C%2Fauthor%3E%3CAN%3E2000885203%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://ac.els-cdn.com/S0140197118300836/1-s2.0-S0140197118300836-main.pdf?_tid=8966687b-bab6-4471-b90b-1079d8b85d11&amp;acdnat=1539256996_b51c65e424b564564203d3b4c19c1b02
VL  - 67
ER  -
TY  - JOUR
AB  - This review summarizes the literature regarding differential reinforcement of other behaviors (DRO) to treat challenging behavior among children with autism spectrum disorder (ASD) and determines the quality of studies among the current literature according to the 2014 Council for Exceptional Children (CEC): Standards for Evidence-Based Practices in Special Education. 

Studies that focused on the use of DRO in the treatment of challenging behavior for individuals with ASD were included for systematic analysis. 

Forty-five studies were identified for inclusion in this review and were evaluated using the eight quality indicators described by the CEC. To the authors&#039; knowledge, this is the only systematic review of the literature that evaluates DRO as an intervention for individuals diagnosed with ASD. 

Principle findings, practical recommendations, and areas of future research are discussed.
AD  - [Weston, Regan; Hodges, Abby; Davis, Tonya N.] Baylor Univ, One Bear Pl 97031, Waco, TX 76798 USA.Weston, R (reprint author), Baylor Univ, One Bear Pl 97031, Waco, TX 76798 USA.Regan_Weston@baylor.edu
AN  - WOS:000434315700005
AU  - Weston,
AU  - R.
AU  - Hodges,
AU  - A.
AU  - Davis,
AU  - T.
AU  - N.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0145445517743487
J2  - Behav. Modificat.
KW  - differential reinforcement of other behavior
KW  - DRO
KW  - zero rate
KW  - omission
KW  - nonoccurrence
KW  - systematic review
KW  - self-injurious-behavior
KW  - vocal stereotypy
KW  - dro schedules
KW  - automatic
KW  - reinforcement
KW  - severe disabilities
KW  - spectrum disorders
KW  - aberrant
KW  - behavior
KW  - students
KW  - reduce
KW  - contingencies
KW  - Psychology
L1  - internal-pdf://1682059744/Weston-2018-Differential Reinforcement of Othe.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: GI4BKTimes Cited: 1Cited Reference Count: 68Weston, Regan Hodges, Abby Davis, Tonya N.1Sage publications incThousand oaks1552-4167Si
PY  - 2018
SP  - 584-609
T2  - Behavior Modification
TI  - Differential Reinforcement of Other Behaviors to Treat Challenging Behaviors Among Children With Autism: A Systematic and Quality Review
UR  - &lt;Go to ISI&gt;://WOS:000434315700005
VL  - 42
ER  -
TY  - JOUR
AB  - **Objective: **
To update and extend our previous systematic review on first- (FGAs) and second-generation antipsychotics (SGAs) for treatment of psychiatric and behavioral conditions in children, adolescents, and young adults (aged &lt;=24 years). This article focuses on the evidence for harms. 

**Method: **
We searched (to April 2016) 8 databases, gray literature, trial registries, Food and Drug Administration reports, and reference lists. Two reviewers conducted study screening and selection independently, with consensus for selection. One reviewer extracted and another verified all data; 2 reviewers independently assessed risk of bias. We conducted meta-analyses when appropriate and network meta-analysis across conditions for changes in body composition. Two reviewers reached consensus for ratings on the strength of evidence for prespecified outcomes. 

**Results:**
A total of 135 studies (95 trials and 40 observational) were included, and 126 reported on harms. FGAs caused slightly less weight gain and more extrapyramidal symptoms than SGAs. SGAs as a class caused adverse effects, including weight gain, high triglyceride levels, extrapyramidal symptoms, sedation, and somnolence. They appeared to increase the risk for high cholesterol levels and type 2 diabetes. Many outcomes for individual drug comparisons were of low or insufficient strength of evidence. Olanzapine caused more short-term gains in weight and body mass index than several other SGAs. The dose of SGAs may not make a difference over the short term for some outcomes. 

**Conclusions: **
Clinicians need to weigh carefully the benefit-to-harm ratio when using antipsychotics, especially when treatment alternatives exist. More evidence is needed on the comparative harms between antipsychotics over the longer term. 

Copyright &copy; 2018, The Author(s) 2018.
AD  - (Pillay, Newton, Hartling, Vandermeer, Nuspl, MacGregor, Featherstone) University of Alberta Evidence-based Practice Center, Edmonton, Alberta, Canada (Boylan) Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada (Newton, Hartling) Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada (Carrey) Douglas Research Institute and IWK Health Centre, Halifax, Nova Scotia, Canada (Carrey) Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, CanadaJ. Pillay, University of Alberta Evidence-based Practice Center, Edmonton, Alberta, Canada
AN  - 622472848
AU  - Pillay,
AU  - J.
AU  - Boylan,
AU  - K.
AU  - Newton,
AU  - A.
AU  - Hartling,
AU  - L.
AU  - Vandermeer,
AU  - B.
AU  - Nuspl,
AU  - M.
AU  - MacGregor,
AU  - T.
AU  - Featherstone,
AU  - R.
AU  - Carrey,
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0706743718779950
DP  - Ovid Technologies
KW  - antipsychotic agents
KW  - children
KW  - pediatric
KW  - systematic review
KW  - young adult
KW  - adolescent
KW  - adult
KW  - adverse drug reaction
KW  - article
KW  - body composition
KW  - body mass
KW  - body weight gain
KW  - child
KW  - cholesterol level
KW  - extrapyramidal symptom
KW  - female
KW  - food and drug administration
KW  - human
KW  - male
KW  - meta analysis
KW  - network meta analysis
KW  - non insulin dependent diabetes mellitus
KW  - risk assessment
KW  - sedation
KW  - side effect
KW  - somnolence
KW  - triacylglycerol level
KW  - olanzapine
L1  - internal-pdf://2447382277/Pillay-2018-Harms of Antipsychotics in Childre.pdf
LA  - English
M3  - In Press
N1  - Using Smart Source ParsingDate of Publication: 2018
PY  - 2018
T2  - Canadian Journal of Psychiatry.
TI  - Harms of Antipsychotics in Children and Young Adults: A Systematic Review Update
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=622472848
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1177%2F0706743718779950&amp;issn=0706-7437&amp;isbn=&amp;volume=&amp;issue=&amp;spage=0706743718&amp;pages=&amp;date=2018&amp;title=Canadian+Journal+of+Psychiatry&amp;atitle=Avantages+et+inconvenients+des+antipsychotiques+chez+les+enfants+et+les+jeunes+adultes+%3A+mise+a+jour+d%27une+revue+systematique&amp;aulast=Pillay&amp;pid=%3Cauthor%3EPillay+J.%3C%2Fauthor%3E%3CAN%3E622472848%3C%2FAN%3E%3CDT%3EArticle+In+Press%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Bakgrunn** 
Vold mot barn er et viktig folkehelseproblem. Millioner av barn over hele verden opple‐ ver vold. Det fins mye dokumentasjon som knytter vold i tidlig alder til psykiske problemer, som depresjon, angst, og atferdsproblemer som selvmordsforsøk, selvskading og dårlig arbeidsdeltakelse. Dersom virkningsfulle tiltak kan identifiseres vil de hjelpe barn til å holde seg friske, gjøre dem i stand til å leve et aktivt og produktivt liv, bidra til samfunnet og nyte livet. 
Problemstilling Formålet med denne oversikten over oversikter var å undersøke effekten av ulike tiltak for barn som har vært utsatt for vold i nære relasjoner. 

**Metoder** 
Vi utførte en oversikt over oversikter i henhold til Kunnskapssenterets metodehånd‐ bok. Vi søkte etter litteratur i elleve databaser opp til september 2015, uten begrensninger på språk, for å identifisere potensielle relevante systematiske oversikter. To oversiktsforfattere valgte uavhengig av hverandre ut de oversiktene som møtte inklusjonskriteriene. De hentet deretter ut data og vurderte kvaliteten på dokumentasjonen for hovedutfallene (dvs. posttraumatisk stresslidelse, mental helse, uønskede hendelser, kognisjon, livskvalitet, forhold mellom omsorgsperson og barn, plassering) ved hjelp av GRADE tilnærmingen (Grading of Recommendations Assessment, Development and Evaluation). 

**Resultat** 
Vi inkluderte fem systematiske oversikter som var publisert mellom 2008 og 2013. De hadde moderat til høy metodisk kvalitet. Oversiktene inkluderte tiltak rettet mot barn fra 0 til 18 år; &eacute;n oversikt inkludert barn fra 0 til 14 år. Vi klassifiserte tiltakene som psykoterapi eller som behandling i fosterhjem. Sammenligningene var enten et annet aktivt tiltak eller vanlig praksis. Psykoterapeutiske tiltak Seks psykoterapeutiske tiltak ble inkludert: barn‐foreldre psykoterapi, kognitiv at‐ ferdsterapi, gruppe psykoterapi for seksuelt misbrukte jenter, spillterapi, psykodynamisk terapi, og traumefokusert kognitiv atferdsterapi. Utfallene vurdert av disse tiltakene var post‐traumatisk stresslidelse (PTSD), uønskede hendelser, og forhold mellom barn og foreldre eller forsørgere, det vil si tilknytning. Det samlede resultatet i oversikten som omhandlet effekten av traumefokusert kognitiv adferdsterapi (TF‐CBT), indikerer at tiltaket muligens forbedrer symptomer på PTSD litt (3 studier, n = 389; standardisert gjennomsnittsdifferanse (SMD) 0,40, 95% CI 0,20 lavere til 0,60 lavere) 12 uker etter tiltaket. Resten av dokumentasjonen tyder på at det er usikkert om disse tiltakene reduserer symptomene eller forbedrer forholdet mellom forsørger og barn, siden tilliten til dokumentasjonen er svært lav. Behandling i fosterhjem Elleve tiltak med behandling i fosterhjem ble inkludert: Attachment and biobehavioural catch up, Enhanced Foster Care, Fostering Healthy Futures, Fostering Individualized Assistance Programme, Incredible Years, Keeping Foster and Kinship Parents Trained and Supported, Middle School Success, Multidimensional Treatment Foster Care, Nurse Home Visitation, Parent Child Interaction Therapy og Treatment Foster Care. Utfallene som disse tiltakene vurderte var uønskede hendelser, kognisjon, psykisk helse, livskvalitet, forsørger‐barn forhold (tilknytning) og plassering (varighet). Resultatene av disse tiltakene viser at det er usikkert om de forbedrer eller reduserer utfal‐ lene fordi tilliten til dokumentasjonen er svært lav. 

**Diskusjon** 
Vi inkluderte fem systematiske oversikter av moderat til høy metodisk kvalitet som til sammen inkluderte 37 primærstudier. Oversiktene undersøkte effekten av tiltak for barn som har vært utsatt for vold. Resultatene fra disse oversiktene tyder på at &lsquo;Branded&rsquo; og 5‐komponent TF‐CBT reduserer PTSD symptomer litt. Til tross for pågående forskning om temaet er det usikker dokumentasjon når det gjelder effekten av andre psykoterapier (f.eks. CBT, psykodynamisk terapi, og spill‐terapi) og behandling i foster‐ hjem (f.eks. Middle School Success, Enhanced Foster Care) for barn som har vært utsatt for vold. Bare tre oversikter rapporterte om uønskede hendelser. Vi har dessverre fortsatt lite kunnskap om virkningsfulle tiltak for barn som har vært utsatt for vold. 

**Konklusjon** 
Denne oversikten over oversikter identifiserte og oppsummerte informasjon fra fem systematiske oversikter av moderat til høy metodisk kvalitet. Den fant kun dokumentasjon av lav‐ til svært lav kvalitet når det gjelder tiltak for barn som har vært utsatt for vold. Det var svakheter i flere av disse oversiktene som reduserer vår tillit til resultatene og implikasjoner for praksis. Beslutningstakere, helsearbeidere, sosialarbeidere, foreldre og omsorgspersoner som arbeider med barn som har vært utsatt for vold bør informeres om mangelen på solid dokumentasjon om effekten av de nevnte tiltakene når de jobber for å forbedre livene til slike barn.
AU  - Bidonde,
AU  - J.
AU  - Menseses,
AU  - J.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/interventions-children-violence-in-close-relationshils-rapport-2017.pdf
PY  - 2017
T2  - Folkehelseinstituttet
TI  - Effekten av tiltak for barn som har opplevd vold i nære relasjoner: en oversikt over oversikter
ER  -
TY  - JOUR
AB  - A meta-analysis on the efficacy of cognitive-behavior-family treatment (CBFT) on children and adolescents with obsessive-compulsive disorder (OCD) was accomplished. 

The purposes of the study were: (a) to estimate the effect magnitude of CBFT in ameliorating obsessive-compulsive symptoms and reducing family accommodation on pediatric OCD and (b) to identify potential moderator variables of the effect sizes. A literature search enabled us to identify 27 studies that fulfilled our selection criteria. 

The effect size index was the standardized pretest-postest mean change index. For obsessive-compulsive symptoms, the adjusted mean effect size for CBFT was clinically relevant and statistically significant in the posttest (d&lt;inf&gt;adj&lt;/inf&gt; = 1.464). For family accommodation the adjusted mean effect size was also positive and statistically significant, but in a lesser extent than for obsessive-compulsive symptoms (d&lt;inf&gt;adj&lt;/inf&gt; = 0.511). 

Publication bias was discarded as a threat against the validity of the meta-analytic results. Large heterogeneity among effect sizes was found. Better results were found when CBFT was individually applied than in group (d&lt;inf&gt;+&lt;/inf&gt; = 2.429 and 1.409, respectively). CBFT is effective to reduce obsessive-compulsive symptoms, but offers a limited effect for family accommodation. 

Additional modules must be included in CBFT to improve its effectiveness on family accommodation. 

Copyright &copy; 2017 Elsevier Ltd.
AN  - 615427657
AU  - Iniesta-Sepulveda,
AU  - M.
AU  - Rosa-Alcazar,
AU  - A.
AU  - I.
AU  - Sanchez-Meca,
AU  - I.
AU  - Parada-Navas,
AU  - J.
AU  - L.
AU  - Rosa-Alcazar,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.janxdis.2017.03.010
L1  - internal-pdf://2574892114/Iniesta-Sepulve-2017-Cognitive-behavioral high.pdf
PY  - 2017
SP  - 53-64
TI  - Cognitive-behavioral high parental involvement treatments for pediatric obsessive-compulsive disorder: A meta-analysis
UR  - http://www.elsevier.com/inca/publications/store/8/0/1
VL  - 49
ER  -
TY  - JOUR
AB  - The effectiveness of behavior reduction strategies is likely affected by any number of ancillary variables. The purpose of this study was to provide a quantitative review of school-based behavior reduction interventions and some ancillary variables that may modulate the effectiveness of those interventions. 

Tau-U, an effect size statistic for single-case designs that takes into account level and trend, was calculated across studies, allowing for examination of several moderator variables including type of functional behavior assessment method used. Moderate intervention effects were found across all studies with a small yet insignificant difference between function- and nonfunction-based interventions. 

The largest difference in a moderator variable was intervention setting, with studies conducted in the natural environment producing larger effects than those in pull-out settings. Possible explanations for these findings, limitations of the study, and areas of future research are discussed. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AD  - Bruni, Teryn P.: tbruni@med.umich.eduBruni, Teryn P.: Michigan Medicine, 1500 East Medical Center Drive, Medical Professions Building D2214, Ann Arbor, MI, US, 48109, tbruni@med.umich.eduBruni, Teryn P.: Michigan Medicine, MI, USDrevon, Daniel: Central Michigan University, Mt Pleasant, MI, USHixson, Michael: Central Michigan University, Mt Pleasant, MI, USWyse, Robert: Central Michigan University, Mt Pleasant, MI, USCorcoran, Samantha: Central Michigan University, Mt Pleasant, MI, USFursa, Sophie: Central Michigan University, Mt Pleasant, MI, US
AN  - 2017-07893-001
AU  - Bruni,
AU  - T.
AU  - P.
AU  - Drevon,
AU  - D.
AU  - Hixson,
AU  - M.
AU  - Wyse,
AU  - R.
AU  - Corcoran,
AU  - S.
AU  - Fursa,
AU  - S.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/pits.22007
DP  - Ovid Technologies
KW  - functional behavior assessment, school-based intervention, intervention effectiveness
KW  - *Behavioral Assessment
KW  - *Functional Analysis
KW  - *School Based Intervention
KW  - Curriculum &amp; Programs &amp; Teaching Methods [3530]
KW  - Human
L1  - internal-pdf://0358761449/bruni2017.pdf
LA  - English
M3  - Meta Analysis
PY  - 2017
SP  - 351-369
T2  - Psychology in the Schools
TI  - The effect of functional behavior assessment on school-based interventions: A meta-analysis of single-case research
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-07893-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1002%2Fpits.22007&amp;issn=0033-3085&amp;isbn=&amp;volume=54&amp;issue=4&amp;spage=351&amp;pages=351-369&amp;date=2017&amp;title=Psychology+in+the+Schools&amp;atitle=The+effect+of+functional+behavior+assessment+on+school-based+interventions%3A+A+meta-analysis+of+single-case+research.&amp;aulast=Bruni&amp;pid=%3Cauthor%3EBruni%2C+Teryn+P%3C%2Fauthor%3E%3CAN%3E2017-07893-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 54
ER  -
TY  - JOUR
AB  - In this study, we evaluate the efficacy and safety of interpersonal psychotherapy (IPT) for adolescents with depression. We searched our existing database and electronic databases, including PubMed, Cochrane, EMBASE, PsycINFO, Web of Science, and CINAHL databases (from inception to May 2016). 

We included randomized controlled trials comparing IPT with various control conditions, including waitlist, psychological placebo, treatment as usual, and no treatment, in adolescents with depression. Finally, we selected seven studies comprising 538 participants comparing IPT with three different control conditions. 

Pooled analyses suggested that IPT was significantly more effective than control conditions in reducing depressive symptoms at post-treatment and follow-up, and increasing the response/remission rate at post-treatment. IPT was also superior to control conditions for all-cause discontinuation and quality of life/functioning improvement outcomes. However, there was no evidence that IPT reduces the risk of suicide from these data. 

Meta-analysis demonstrated publication bias for primary efficacy, while the adjusted standardized mean difference using the trim-and-fill method indicated IPT was still significantly superior to the control conditions. Current evidence indicates IPT has a superior efficacy and acceptability compared with control conditions in treating adolescents with depression. 

Copyright &copy; 2017
AN  - 615176802
AU  - Pu,
AU  - J.
AU  - Zhou,
AU  - X.
AU  - Liu,
AU  - L.
AU  - Zhang,
AU  - Y.
AU  - Yang,
AU  - L.
AU  - Yuan,
AU  - S.
AU  - Zhang,
AU  - H.
AU  - Han,
AU  - Y.
AU  - Zou,
AU  - D.
AU  - Xie,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.psychres.2017.03.023
L1  - internal-pdf://0829339584/Pu-2017-Efficacy and acceptability of interper.pdf
PY  - 2017
SP  - 226-232
TI  - Efficacy and acceptability of interpersonal psychotherapy for depression in adolescents: A meta-analysis of randomized controlled trials
UR  - http://www.elsevier.com/locate/psychres
VL  - 253
ER  -
TY  - JOUR
AB  - The aim of the present study was to investigate the impact of Social Emotional Learning (SEL) programs on different youth behavioral outcomes. 

The previous meta-analysis on school-based SEL programs reported a small but significant effect of SEL on the emotional and behavioral outcomes. 

We found 33 articles with 37 studies, with 32 742 subjects, comparing an intervention with a control group to assess the effect of SEL program. 

Results have shown a statistically significant effect size for programs delivering SEL (g = .31). Significant effect sizes were reported for specific outcomes involved in the analysis. 

Concluding, our meta-analysis supports the previous findings from the scientific literature regarding the impact of SEL programs. Practical implications are discussed. 

(PsycINFO Database Record (c) 2019 APA, all rights reserved)
AN  - 2018-65577-002
AU  - Boncu,
AU  - A.
AU  - Costea,
AU  - I.
AU  - Minulescu,
AU  - M.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.24913/rjap.19.2.02
L1  - internal-pdf://1045895051/Boncu-2017-A meta-analytic study investigating.pdf
PY  - 2017
SP  - 35-41
T2  - Romanian Journal of Applied Psychology
TI  - A meta-analytic study investigating the efficiency of socio-emotional learning programs on the development of children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2018-65577-002
VL  - 19
ER  -
TY  - JOUR
AB  - Depression in youth is prevalent and disabling and tends to presage a chronic and recurrent course of illness and impairment in adulthood. Clinical trial research in youth depression has a 30-year history, and evidence-based treatment reviews appeared in 1998 and 2008. 

The current review of 42 randomized controlled trials (RCTs) updates these reviews to include RCTs published between 2008 and 2014 (N = 14) and reevaluates previously reviewed literature. Given the growing maturity of the field, this review utilized a stringent set of methodological criteria for trial inclusion, most notable for excluding trials based in subclinical samples of youth that had been included in previous reviews (N = 12) and including well-designed RCTs with null and negative findings (N = 8). 

Findings from the current review suggest that evidence for child treatments is notably weaker than for adolescent interventions, with no child treatments achieving well-established status and the evidentiary basis of treatments downgraded from previous reports. Cognitive behavioral therapy (CBT) for clinically depressed children appears to be possibly efficacious, with mixed findings across trials. For depressed adolescents, both CBT and interpersonal psychotherapy are well-established interventions, with evidence of efficacy in multiple trials by independent investigative teams.

This positive conclusion is tempered by the small size of the interpersonal psychotherapy literature (N = 6) and concern that CBT effects may be attenuated in clinically complicated samples and when compared against active control conditions. Data on predictors, moderators, and mediators are examined and priorities for future research discussed.
AD  - Weersing, V Robin. a SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology. Weersing, V Robin. b Department of Psychology , San Diego State University. Jeffreys, Megan. a SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology. Do, Minh-Chau T. a SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology. Schwartz, Karen T G. a SDSU/UC San Diego Joint Doctoral Program in Clinical Psychology. Bolano, Carl. b Department of Psychology , San Diego State University.
AN  - 27870579
AU  - Weersing,
AU  - V.
AU  - R.
AU  - Jeffreys,
AU  - M.
AU  - Do,
AU  - M-C.
AU  - T.
AU  - Schwartz,
AU  - K.
AU  - T.
AU  - Bolano,
AU  - C,
DA  - Jan-Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15374416.2016.1220310
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
L1  - internal-pdf://1418848529/Evidence Base Update of Psychosocial Treatment.pdf
LA  - English
N1  - Weersing, V Robin Jeffreys, Megan Do, Minh-Chau T Schwartz, Karen T G Bolano, Carl
PY  - 2017
SP  - 11-43
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Evidence Base Update of Psychosocial Treatments for Child and Adolescent Depression
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27870579http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27870579&amp;id=doi:10.1080%2F15374416.2016.1220310&amp;issn=1537-4416&amp;isbn=&amp;volume=46&amp;issue=1&amp;spage=11&amp;pages=11-43&amp;date=2017&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Evidence+Base+Update+of+Psychosocial+Treatments+for+Child+and+Adolescent+Depression.&amp;aulast=Weersing&amp;pid=%3Cauthor%3EWeersing+VR%3C%2Fauthor%3E%3CAN%3E27870579%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 46
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Autism spectrum disorders (ASDs) are pervasive and multifactorial neurodevelopmental conditions, characterized by impairments in social communication and interaction, and restricted, repetitive patterns of behaviour, interests or activities. Treatment options to ameliorate symptoms of ASDs are limited. Heterogeneity complicates the quest for personalized medicine in this population. Our aim was to investigate if there are baseline characteristics of patients that moderate response or trial design features that impede the identification of efficacious interventions for ASDs. 

**METHOD: **
Literature searches of EMBASE, MEDLINE and PsycINFO identified 43 studies for qualitative assessment of baseline characterization of participants and 37 studies for quantitative analysis of moderators of treatment response. Criteria included blinded randomized controlled trials (RCTs) in paediatric ASD, with at least 10 participants per arm or 20 overall, of oral treatments, including pharmacological interventions and dietary supplements. 

**RESULTS: **
Random-effects meta-analysis of 1997 participants (81% male) identified three moderators associated with an increase in treatment response: trials located in Europe and the Middle-East; outcome measures designated primary status; and the type of outcome measure. Inconsistent reporting of baseline symptom severity and intellectual functioning prevented analysis of these variables. Qualitative synthesis of baseline characteristics identified at least 31 variables, with only age and gender reported in all trials. Biological markers were included in six RCTs. 

**CONCLUSIONS: **
Few trials reported adequate baseline characteristics to permit detailed analysis of response to treatment. Consideration of geographical location, baseline severity and intellectual function is required to ensure generalizability of results. The use of biological markers and correlates in ASD trials remains in its infancy. There is great need to improve the application of baseline characterization and incorporation of biological markers and correlates to permit selection of participants into homogeneous subgroups and to inform response to treatment in ASD.
AD  - Masi, A. Autism Clinic for Translational Research,Brain and Mind Centre,Central Clinical School,Sydney Medical School,University of Sydney,Camperdown,NSW,Australia. Lampit, A. Regenerative Neuroscience Group,Brain and Mind Centre,University of Sydney,Camperdown,NSW,Australia. DeMayo, M M. Autism Clinic for Translational Research,Brain and Mind Centre,Central Clinical School,Sydney Medical School,University of Sydney,Camperdown,NSW,Australia. Glozier, N. Autism Clinic for Translational Research,Brain and Mind Centre,Central Clinical School,Sydney Medical School,University of Sydney,Camperdown,NSW,Australia. Hickie, I B. Autism Clinic for Translational Research,Brain and Mind Centre,Central Clinical School,Sydney Medical School,University of Sydney,Camperdown,NSW,Australia. Guastella, A J. Autism Clinic for Translational Research,Brain and Mind Centre,Central Clinical School,Sydney Medical School,University of Sydney,Camperdown,NSW,Australia.
AN  - 28091344
AU  - Masi,
AU  - A.
AU  - Lampit,
AU  - A.
AU  - DeMayo,
AU  - M.
AU  - M.
AU  - Glozier,
AU  - N.
AU  - Hickie,
AU  - I.
AU  - B.
AU  - Guastella,
AU  - A.
AU  - J.
DA  - Jan 16
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1017/S0033291716003457
DP  - Ovid Technologies
J2  - Psychol Med
L1  - internal-pdf://1568107943/Masi-2017-A comprehensive systematic review an.pdf
LA  - English
N1  - Masi, A Lampit, A DeMayo, M M Glozier, N Hickie, I B Guastella, A J S0033291716003457
PY  - 2017
SP  - 1-12
T2  - Psychological Medicine
TI  - A comprehensive systematic review and meta-analysis of pharmacological and dietary supplement interventions in paediatric autism: moderators of treatment response and recommendations for future research
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28091344http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28091344&amp;id=doi:10.1017%2FS0033291716003457&amp;issn=0033-2917&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-12&amp;date=2017&amp;title=Psychological+Medicine&amp;atitle=A+comprehensive+systematic+review+and+meta-analysis+of+pharmacological+and+dietary+supplement+interventions+in+paediatric+autism%3A+moderators+of+treatment+response+and+recommendations+for+future+research.&amp;aulast=Masi&amp;pid=%3Cauthor%3EMasi+A%3C%2Fauthor%3E%3CAN%3E28091344%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Background: **
Mind-body therapies are often used by people with autism spectrum disorders (ASD). However, there has been little examination into which types of mind-body therapies have been investigated for people with ASD and for what purposes. A systematic review was conducted to evaluate the existing evidence for mind-body therapies for people with ASD, particularly to determine the types of mind-body therapies used and the outcomes that are targeted. 

**Method: **
PubMed, PsychInfo, and Scopus were searched using terms for ASD and mind-body therapies. Sixteen studies were selected for review; these studies tested interventions using mindfulness, meditation, yoga, Nei Yang Gong, and acceptance commitment therapy. Most study outcomes targeted behavior, psychological symptoms, and quality of life for children and adults with ASD as well as their parents. 

**Results: **
There was little overlap between studies on the types of mind-body therapies used and associated outcomes, and only three of the studies were randomized controlled trials. Most studies were small and uncontrolled. Some studies modified the mind-body therapies to increase accessibility for people with ASD. Conclusion: The evidence for mind-body therapies for people with ASD is limited and would benefit from larger randomized controlled trials. 

&copy; Copyright 2017, Mary Ann Liebert, Inc. 2017.
AN  - 616311874
AU  - Hourston,
AU  - S.
AU  - Atchley,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/acm.2016.0336
L1  - internal-pdf://3780029109/Hourston-2017-Autism and Mind-Body Therapies_.pdf
PY  - 2017
SP  - 331-339
TI  - Autism and Mind-Body Therapies: A Systematic Review
UR  - http://www.liebertonline.com/acm
VL  - 23
ER  -
TY  - JOUR
AB  - Child maltreatment is a global problem affecting both high income (HICs) and low and middle income countries (LMICs). However research has shown that children who live in the world&#039;s poorest countries and communities are more likely to suffer from abuse and neglect. There is some evidence that parenting interventions can assist in the prevention of child maltreatment, but most of this research has been conducted in HICs. 

The main aim of this review was to examine the evidence from previous systematic reviews on the role of parenting programmes in the prevention of violence against children in both HICs and LMICs. 

A comprehensive internet search was conducted for published and unpublished reviews. After reviewing abstracts and full texts against established criteria for inclusion in the study, 28 reviews (20 systematic reviews/meta-analyses and 8 comprehensive reviews) were used in the analyses. 

The findings suggest that parenting programmes have the potential to both prevent and reduce the risk of child maltreatment. However, there is lack of good evidence from LMICs where the risk of child maltreatment is greatest. 

Implications for policy and future research are discussed, especially for the LMIC context.
AD  - Coore Desai, Charlene. a Department of Child &amp; Adolescent Health , University of the West Indies , Mona, Kingston , Jamaica. Reece, Jody-Ann. a Department of Child &amp; Adolescent Health , University of the West Indies , Mona, Kingston , Jamaica. Shakespeare-Pellington, Sydonnie. a Department of Child &amp; Adolescent Health , University of the West Indies , Mona, Kingston , Jamaica.
AN  - 28133982
AU  - Coore
AU  - Desai,
AU  - C.
AU  - Reece,
AU  - J.
AU  - A.
AU  - Shakespeare-Pellington,
AU  - S.
DA  - Jan 29
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/13548506.2016.1271952
DP  - Ovid Technologies
J2  - Psychol Health Med
L1  - internal-pdf://2104538217/The prevention of violence in childhood throug.pdf
LA  - English
N1  - Coore Desai, Charlene Reece, Jody-Ann Shakespeare-Pellington, Sydonnie
PY  - 2017
SP  - 1-21
T2  - Psychology Health and Medicine
TI  - The prevention of violence in childhood through parenting programmes: a global review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28133982http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28133982&amp;id=doi:10.1080%2F13548506.2016.1271952&amp;issn=1354-8506&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-21&amp;date=2017&amp;title=Psychology+Health+%26+Medicine&amp;atitle=The+prevention+of+violence+in+childhood+through+parenting+programmes%3A+a+global+review.&amp;aulast=Coore+Desai&amp;pid=%3Cauthor%3ECoore+Desai+C%3C%2Fauthor%3E%3CAN%3E28133982%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Background**
This is an update of the original Cochrane Review, last published in 2012 (Loy 2012). Children and youths with disruptive behaviour disorders may present to health services, where they may be treated with atypical antipsychotics. There is increasing usage of atypical antipsychotics in the treatment of disruptive behaviour disorders.

**Objectives**
To evaluate the effect and safety of atypical antipsychotics, compared to placebo, for treating disruptive behaviour disorders in children and youths. The aim was to evaluate each drug separately rather than the class effect, on the grounds that each atypical antipsychotic has different pharmacologic binding profile (Stahl 2013) and that this is clinically more useful.

**Search methods**
In January 2017, we searched CENTRAL, MEDLINE, Embase, five other databases and two trials registers.

**Selection criteria**
Randomised controlled trials of atypical antipsychotics versus placebo in children and youths aged up to and including 18 years, with a diagnosis of disruptive behaviour disorders, including comorbid ADHD. The primary outcomes were aggression, conduct problems and adverse events (i.e. weight gain/changes and metabolic parameters). The secondary outcomes were general functioning, noncompliance, other adverse events, social functioning, family functioning, parent satisfaction and school functioning.

**Data collection and analysis**
We used standard methodological procedures expected by Cochrane. Two review authors (JL and KS) independently collected, evaluated and extracted data. We used the GRADE approach to assess the quality of the evidence. We performed meta‐analyses for each of our primary outcomes, except for metabolic parameters, due to inadequate outcome data.

**Main results**
We included 10 trials (spanning 2000 to 2014), involving a total of 896 children and youths aged five to 18 years. Bar two trials, all came from an outpatient setting. Eight trials assessed risperidone, one assessed quetiapine and one assessed ziprasidone. Nine trials assessed acute efficacy (over four to 10 weeks); one of which combined treatment with stimulant medication and parent training. One trial was a six‐month maintenance trial assessing symptom recurrence.

The quality of the evidence ranged from low to moderate. Nine studies had some degree of pharmaceutical support/funding.

**Primary outcomes**

Using the mean difference (MD), we combined data from three studies (238 participants) in a meta‐analysis of aggression, as assessed using the Aberrant Behaviour Checklist (ABC) ‒ Irritability subscale. We found that youths treated with risperidone show reduced aggression compared to youths treated with placebo (MD &minus;6.49, 95% confidence interval (CI) &minus;8.79 to &minus;4.19; low‐quality evidence). Using the standardised mean difference (SMD), we pooled data from two risperidone trials (190 participants), which used different scales: the Overt Aggression Scale ‒ Modified (OAS‐M) Scale and the Antisocial Behaviour Scale (ABS); as the ABS had two subscales that could not be combined (reactive and proactive aggression), we performed two separate analyses. When we combined the ABS Reactive subscale and the OAS‐M, the SMD was &minus;1.30 in favour of risperidone (95% CI &minus;2.21 to &minus;0.40, moderate‐quality evidence). When we combined the ABS Proactive subscale and OAS‐M, the SMD was &minus;1.12 (95% CI &minus;2.30 to 0.06, moderate‐quality evidence), suggesting uncertainty about the estimate of effect, as the confidence intervals overlapped the null value. In summary, there was some evidence that aggression could be reduced by risperidone. Data were lacking on other atypical antipsychotics, like quetiapine and ziprasidone, with regard to their effects on aggression.

We pooled data from two risperidone trials (225 participants) in a meta‐analysis of conduct problems, as assessed using the Nisonger Child Behaviour Rating Form ‒ Conduct Problem subscale (NCBRF‐CP). This yielded a final mean score that was 8.61 points lower in the risperidone group compared to the placebo group (95% CI &minus;11.49 to &minus;5.74; moderate‐quality evidence).

We investigated the effect on weight by performing two meta‐analyses. We wanted to distinguish between the effects of antipsychotic medication only and the combined effect with stimulants, since the latter can have a counteracting effect on weight gain due to appetite suppression. Pooling two trials with risperidone only (138 participants), we found that participants on risperidone gained 2.37 kilograms (kg) more (95% CI 0.26 to 4.49; moderate‐quality evidence) than those on placebo. When we added a trial where all participants received a combination of risperidone and stimulants, we found that those on the combined treatment gained 2.14 kg more (95% CI 1.04 to 3.23; 3 studies; 305 participants; low‐quality evidence) than those on placebo.

**Secondary outcomes**

Out of the 10 included trials, three examined general functioning, social functioning and parent satisfaction. No trials examined family or school functioning. Data on non‐compliance/attrition rate and other adverse events were available from all 10 trials.

**Authors&#039; conclusions**
There is some evidence that in the short term risperidone may reduce aggression and conduct problems in children and youths with disruptive behaviour disorders There is also evidence that this intervention is associated with significant weight gain.

For aggression, the difference in scores of 6.49 points on the ABC ‒ Irritability subscale (range 0 to 45) may be clinically significant. It is challenging to interpret the clinical significance of the differential findings on two different ABS subscales as it may be difficult to distinguish between reactive and proactive aggression in clinical practice. For conduct problems, the difference in scores of 8.61 points on the NCBRF‐CP (range 0 to 48) is likely to be clinically significant. Weight gain remains a concern.

Caution is required in interpreting the results due to the limitations of current evidence and the small number of high‐quality trials. There is a lack of evidence to support the use of quetiapine, ziprasidone or any other atypical antipsychotic for disruptive behaviour disorders in children and youths and no evidence for children under five years of age. It is uncertain to what degree the efficacy found in clinical trials will translate into real‐life clinical practice. Given the effectiveness of parent‐training interventions in the management of these disorders, and the somewhat equivocal evidence on the efficacy of medication, it is important not to use medication alone. This is consistent with current clinical guidelines.
AU  - Loy,
AU  - J.
AU  - H.
AU  - Merr,
AU  - S.
AU  - N.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Stasiak,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD008559.pub3
PY  - 2017
T2  - Cochrane Database of Systematic Reviews
TI  - Atypical antipsychotics for disruptive behaviour disorders in children and youths
ER  -
TY  - JOUR
AB  - Sleep problems are common in children with autism spectrum disorder (ASD). This meta-synthesis collated eight previously published systematic reviews examining the efficacy of sleep interventions in children with ASD in an attempt to present a clear analysis of trialed interventions. 

The collated reviews consider five major groups of sleep interventions for children with ASD: melatonin therapy, pharmacologic treatments other than melatonin, behavioral interventions, parent education/education programs, and alternative therapies (massage therapy, aromatherapy, and multivitamin and iron supplementation). 

These eight reviews were based on 38 original studies and address the efficacy of interventions across 17 sleep problem domains. The results of this meta-synthesis suggest that no single intervention is effective across all sleep problems in children with ASD. 

However, melatonin, behavioral interventions, and parent education/education program interventions appear the most effective at ameliorating multiple domains of sleep problems compared with other interventions. Due to the heterogeneous causative factors and presentations of disordered sleep, further research into the effectiveness of sleep interventions may target specific phenotypic subgroups rather than a broad analysis across the general ASD population. 

Similarly, future research needs to consider the efficacy of different polytherapeutic approaches in order to provide clinicians with evidence to inform best practice. In the meantime, this review supports clinicians&#039; decision making for a majority of the identified sleep problems in the ASD population. 

Copyright This article is protected by copyright. All rights reserved.
AN  - 28258648
AU  - Cuomo,
AU  - B.
AU  - M.
AU  - Vaz,
AU  - S.
AU  - Lee,
AU  - E.
AU  - A.
AU  - Thompson,
AU  - C.
AU  - Rogerson,
AU  - J.
AU  - M.
AU  - Falkmer,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/phar.1920
L1  - internal-pdf://3589223502/Cuomo-2017-Effectiveness of Sleep-Based Interv.pdf
PY  - 2017
SP  - 04
TI  - Effectiveness of Sleep-Based Interventions for Children with Autism Spectrum Disorder: A Meta-synthesis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28258648
VL  - 04
ER  -
TY  - JOUR
AB  - **PURPOSE: **
Depression is currently the leading cause of illness and disability in young people. Evidence suggests that behavioural activation (BA) is an effective treatment for depression in adults but less research focuses on its application with young people. This review therefore examined whether BA is effective in the treatment of depression in young people. 

**METHODS: **
A systematic review (International Prospective Register of Systematic Reviews reference: CRD42015020453), following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, was conducted to examine studies that had explored behavioural interventions for young people with depression. The electronic databases searched included the Cochrane Library, EMBASE, MEDLINE, CINAHL Plus, PsychINFO, and Scopus. A meta-analysis employing a generic inverse variance, random-effects model was conducted on the included randomized controlled trials (RCTs) to examine whether there were overall effects of BA on the Children&#039;s Depression Rating Scale - Revised. 

**RESULTS: **
Ten studies met inclusion criteria: three RCTs and seven within-participant designs (total n = 170). The review showed that BA may be effective in the treatment of depression in young people. The Cochrane risk of bias tool and the Moncrieff scale used to assess the quality of the included studies revealed a variety of limitations within each. 

**CONCLUSIONS: **
Despite demonstrating that BA may be effective in the treatment of depression in young people, the review indicated a number of methodological problems in the included studies meaning that the results and conclusions should be treated with caution. Furthermore, the paucity of studies in this area highlights the need for further research. 

**PRACTITIONER POINTS: **
Currently BA is included within National Institute for Health and Clinical Excellence (NICE, 2009) guidelines as an evidence-based treatment for depression in adults with extensive research supporting its effectiveness. It is important to investigate whether it may also be effective in treating young people. Included studies reported reductions in depression scores across a range of measures following BA. BA may be an effective treatment of depression in young people.
AN  - 28299896
AU  - Tindall,
AU  - L.
AU  - Mikocka-Walus,
AU  - A.
AU  - McMillan,
AU  - D.
AU  - Wright,
AU  - B.
AU  - Hewitt,
AU  - C.
AU  - Gascoyne,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/papt.12121
L1  - internal-pdf://1439704432/Tindall-2017-Is behavioural activation effecti.pdf
PY  - 2017
SP  - 770-796
T2  - Psychology &amp; Psychotherapy: Theory, Research &amp; Practice
TI  - Is behavioural activation effective in the treatment of depression in young people? A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28299896
VL  - 90
ER  -
TY  - JOUR
AB  - **Objective **
To analyze the effectiveness of psychological treatments on symptom load and associated disability in children with functional somatic symptoms, and to explore potential moderators of effects. 

**Study design **
Cochrane, PubMed, PsycINFO, EMBASE, and CINAHL were searched for randomized controlled trials published in peer-reviewed journals. Randomized controlled trials studying the effect of a psychological treatment on symptom load and disability in children with functional somatic symptoms were selected. Data on symptom load, disability, and school absence directly post-treatment and at follow-up were extracted by 2 assessors. Studies were appraised with the Cochrane risk of bias tool. Standardized mean differences were pooled in a random-effects model. Heterogeneity in effect-sizes was explored by use of meta-regressions. PROSPERO Registration ID: CRD42015029667. 

**Results **
Out of 4098 identified records, 27 studies were included in this review of which 21 were included in meta-analyses. Psychological treatments reduced symptom load (Hedges g = -0.61), disability (Hedges g = -0.42), and school absence (Hedges g = -0.51) post-treatment in children suffering from various functional somatic symptoms. Effects were maintained at follow-up. Type and duration of symptoms, age, and treatment dose did not explain heterogeneity in effect-sizes between studies. Effect-sizes should be interpreted with caution because of the variety in outcome measures, unexplained heterogeneity in found effects and potential publication bias. 

**Conclusions **
Psychological interventions reduce symptom load, disability, and school absence in children with functional somatic symptoms. Future research should clarify which patient and treatment characteristics modify outcomes. 

Copyright &copy; 2017 Elsevier Inc.
AN  - 615424634
AU  - Bonvanie,
AU  - I.
AU  - J.
AU  - Kallesoe,
AU  - K.
AU  - H.
AU  - Janssens,
AU  - K.
AU  - A.
AU  - M.
AU  - Schroder,
AU  - A.
AU  - Rosmalen,
AU  - J.
AU  - G.
AU  - M.
AU  - Rask,
AU  - C.
AU  - U.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jpeds.2017.03.017
L1  - internal-pdf://1373520638/Bonvanie-2017-Psychological Interventions for.pdf
PY  - 2017
SP  - 272-281.e17
TI  - Psychological Interventions for Children with Functional Somatic Symptoms: A Systematic Review and Meta-Analysis
UR  - http://www.elsevier.com/inca/publications/store/6/2/3/3/1/1/index.htt
VL  - 187
ER  -
TY  - JOUR
AB  - Group-based social skills interventions (GSSIs) are widely used for treating social competence among youth with autism spectrum disorder (ASD), but their efficacy is unclear. 

Previous meta-analysis of the literature on well-designed trials of GSSIs is limited in size and scope, collapsing across highly heterogeneous sources (parents; youths; teachers; observers; behavioral tasks). 

The current meta-analysis of randomized control trials (RCTs) was conducted to ascertain overall effectiveness of GSSIs and differences by reporting sources. Nineteen RCTs met inclusion criteria. Results show that overall positive aggregate effects were medium (g=0.51, p&lt;0.001). 

Effects were large for self-report (g=0.92, p&lt;0.001), medium for task-based measures (g=0.58, p&lt;0.001), small for parent- and observer-report (g=0.47 and 0.40, respectively, p&lt;0.001), and nonsignificant for teacher-report (p=0.11). Moderation analyses of self-report revealed the effect was wholly attributable to youth reporting that they learned about skilled social behaviors (social knowledge; g=1.15, p&lt;0.01), but not that they enacted them (social performance; g=0.28, p=0.31). 

Social skills interventions presently appear modestly effective for youth with ASD, but may not generalize to school settings or self-reported social behavior. 

Copyright &copy; 2017 Elsevier Ltd. All rights reserved.
AD  - Gates, Jacquelyn A. Stony Brook University, United States. Kang, Erin. Stony Brook University, United States. Lerner, Matthew D. Stony Brook University, United States. Electronic address: matthew.lerner@stonybrook.edu.
AN  - 28130983
AU  - Gates,
AU  - J.
AU  - A.
AU  - Kang,
AU  - E.
AU  - Lerner,
AU  - M.
AU  - D.
DA  - Jan 18
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2017.01.006
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://1916922977/Gates-2017-Efficacy of group social skills int.pdf
LA  - English
M3  - Review
N1  - Gates, Jacquelyn A Kang, Erin Lerner, Matthew D S0272-7358(16)30352-X
PY  - 2017
SP  - 164-181
T2  - Clinical Psychology Review
TI  - Efficacy of group social skills interventions for youth with autism spectrum disorder: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28130983http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28130983&amp;id=doi:10.1016%2Fj.cpr.2017.01.006&amp;issn=0272-7358&amp;isbn=&amp;volume=52&amp;issue=&amp;spage=164&amp;pages=164-181&amp;date=2017&amp;title=Clinical+Psychology+Review&amp;atitle=Efficacy+of+group+social+skills+interventions+for+youth+with+autism+spectrum+disorder%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Gates&amp;pid=%3Cauthor%3EGates+JA%3C%2Fauthor%3E%3CAN%3E28130983%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S027273581630352X/1-s2.0-S027273581630352X-main.pdf?_tid=08a6dbe8-04c7-11e7-b137-00000aab0f27&amp;acdnat=1489064034_5f2f22bde8661d92544972973c5d9ae3
VL  - 52
ER  -
TY  - JOUR
AB  - Much of augmentative and alternative communication (AAC) research for individuals with autism spectrum disorder has focused on young children. 

Given that the lives, communication, strengths, and needs of adolescents and adults with autism spectrum disorder are quite different from those of young children, the purpose of the current study was to consolidate current AAC intervention research findings specific to these individuals. 

A systematic review was conducted to identify and evaluate relevant research. Results indicate that AAC intervention benefits adolescents and adults with autism spectrum disorder. 

However, more research is urgently needed. Future research focused on supporting communicative functions other than requesting (e.g., social closeness, information transfer) while participating in contexts important to the lives of adolescents and adults may be particularly valuable.
AN  - 28884601
AU  - Holyfield,
AU  - C.
AU  - Drager,
AU  - K.
AU  - D.
AU  - R.
AU  - Kremkow,
AU  - J.
AU  - M.
AU  - D.
AU  - Light,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/07434618.2017.1370495
L1  - internal-pdf://2187942251/Holyfield-2017-Systematic review of AAC interv.pdf
PY  - 2017
SP  - 201-212
TI  - Systematic review of AAC intervention research for adolescents and adults with autism spectrum disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28884601
VL  - 33
ER  -
TY  - JOUR
AB  - There is a lack of knowledge about specific components that make interventions effective in preventing or reducing child maltreatment. The aim of the present meta-analysis was to increase this knowledge by summarizing findings on effects of interventions for child maltreatment and by examining potential moderators of this effect, such as intervention components and study characteristics. 

Identifying effective components is essential for developing or improving child maltreatment interventions. A literature search yielded 121 independent studies (N = 39,044) examining the effects of interventions for preventing or reducing child maltreatment. From these studies, 352 effect sizes were extracted. The overall effect size was significant and small in magnitude for both preventive interventions (d = 0.26, p &lt; .001) and curative interventions (d = 0.36, p &lt; .001).

Cognitive behavioral therapy, home visitation, parent training, family-based/multisystemic, substance abuse, and combined interventions were effective in preventing and/or reducing child maltreatment. For preventive interventions, larger effect sizes were found for short-term interventions (0-6 months), interventions focusing on increasing self-confidence of parents, and interventions delivered by professionals only. 

Further, effect sizes of preventive interventions increased as follow-up duration increased, which may indicate a sleeper effect of preventive interventions. For curative interventions, larger effect sizes were found for interventions focusing on improving parenting skills and interventions providing social and/or emotional support. Interventions can be effective in preventing or reducing child maltreatment. Theoretical and practical implications are discussed.
AN  - 29204796
AU  - van
AU  - der
AU  - Put,
AU  - C.
AU  - E.
AU  - Assink,
AU  - M.
AU  - Gubbels,
AU  - J.
AU  - Boekhout
AU  - van
AU  - Solinge,
AU  - N.
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-017-0250-5
L1  - internal-pdf://2138221424/van der Put-2017-Identifying Effective Compone.pdf
PY  - 2017
SP  - 04
T2  - Clinical Child &amp; Family Psychology Review
TI  - Identifying Effective Components of Child Maltreatment Interventions: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29204796
UR  - https://link.springer.com/content/pdf/10.1007%2Fs10567-017-0250-5.pdf
VL  - 04
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Children with mental health crises require access to specialised resources and services which are not yet standard in general and paediatric EDs. In 2010, we published a systematic review that provided some evidence to support the use of specialised care models to reduce hospitalisation, return ED visits and length of ED stay. We perform a systematic review to update the evidence base and inform current policy statements. 

**METHODS: **
Twelve databases and the grey literature were searched up to January 2015. Seven studies were included in the review (four newly identified studies). These studies compared ED-based strategies designed to assess, treat and/or therapeutically support or manage a mental health presentation. The methodological quality of six studies was assessed using the Cochrane Effective Practice and Organization of Care Risk of Bias tool (one interrupted time series study) and a modified Newcastle-Ottawa Scale (three retrospective cohort and two before-after studies). The Grading of Recommendations Assessment, Development and Evaluation (GRADE) system was applied to rate overall evidence quality (high, moderate, low or very low) for individual outcomes from these six studies. An additional study evaluated the psychometric properties of a clinical instrument and was assessed using criteria developed by the Society of Pediatric Psychology Assessment Task Force (well-established, approaching well-established or promising assessment). 

**RESULTS: **
There is low to very low overall evidence quality that: (1) use of screening laboratory tests to medically clear mental health patients increases length of ED stay and costs, but does not increase the risk of clinical management or disposition change if not conducted; and (2) specialised models of ED care reduce lengths of ED stay, security man-hours and restraint orders. One mental health assessment tool of promising quality, the home, education, activities and peers, drugs and alcohol, suicidality, emotions and behaviour, discharge resources (HEADS-ED), has had good accuracy in predicting admission to inpatient psychiatry. 

**CONCLUSIONS: **
Lower-quality data suggest benefits to the use of specialised resources and services for paediatric mental health care in general and paediatric EDs. Experimental evaluation of strategies and the inclusion of patient-reported outcomes will improve confidence in these findings. Additional psychometric studies are needed for the HEADS-ED tool to be considered well established. 

Copyright &copy; Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. 
All rights reserved. No commercial use is permitted unless otherwise expressly granted.
AN  - 28119350
AU  - Newton,
AU  - A.
AU  - S.
AU  - Hartling,
AU  - L.
AU  - Soleimani,
AU  - A.
AU  - Kirkland,
AU  - S.
AU  - Dyson,
AU  - M.
AU  - P.
AU  - Cappelli,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/emermed-2016-205939
L1  - internal-pdf://1060685969/Newton-2017-A systematic review of management.pdf
PY  - 2017
SP  - 376-384
TI  - A systematic review of management strategies for children&#039;s mental health care in the emergency department: update on evidence and recommendations for clinical practice and research
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28119350
VL  - 34
ER  -
TY  - JOUR
AB  - The incidence of violence in dating relationships has a significant impact on young people, including decreased mental and physical health. 

This review is the first to provide a quantitative synthesis of empirical evaluations of school-based programs implemented in middle and high schools that sought to prevent or reduce incidents of dating violence. 

After a systematic search and screening procedure, a meta-analysis of 23 studies was used to examine the effects of school-based programs. 

Results indicated school-based programs influence dating violence knowledge (g = 0.22, 95% confidence interval [0.05, 0.39]) and attitudes (g = 0.14, 95% confidence interval [0.10, 0.19]); however, to date, the results for dating violence perpetration and victimization indicate programs are not affecting these behaviors to a significant extent. 

The results of this review are encouraging, but they also highlight the need for modifications to dating violence prevention programs including the incorporation of skill-building components and a need to address the role of bystanders. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-10619-002
AU  - De
AU  - La
AU  - Rue,
AU  - L.
AU  - Polanin,
AU  - J.
AU  - R.
AU  - Espelage,
AU  - D.
AU  - L.
AU  - Pigott,
AU  - T.
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://doi.org/10.3102/0034654316632061
L1  - internal-pdf://0781475996/De La Rue-2017-A meta-analysis of school-based.pdf
PY  - 2017
SP  - 7-34
TI  - A meta-analysis of school-based interventions aimed to prevent or reduce violence in teen dating relationships
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-10619-002
VL  - 87
ER  -
TY  - JOUR
AB  - **Background**
Tobacco use is estimated to kill 7 million people a year. Nicotine is highly addictive, but surveys indicate that almost 70% of US and UK smokers would like to stop smoking. Although many smokers attempt to give up on their own, advice from a health professional increases the chances of quitting. As of 2016 there were 3.5 billion Internet users worldwide, making the Internet a potential platform to help people quit smoking.

**Objectives**
To determine the effectiveness of Internet‐based interventions for smoking cessation, whether intervention effectiveness is altered by tailoring or interactive features, and if there is a difference in effectiveness between adolescents, young adults, and adults.

**Search methods**
We searched the Cochrane Tobacco Addiction Group Specialised Register, which included searches of MEDLINE, Embase and PsycINFO (through OVID). There were no restrictions placed on language, publication status or publication date. The most recent search was conducted in August 2016.

**Selection criteria**
We included randomised controlled trials (RCTs). Participants were people who smoked, with no exclusions based on age, gender, ethnicity, language or health status. Any type of Internet intervention was eligible. The comparison condition could be a no‐intervention control, a different Internet intervention, or a non‐Internet intervention. To be included, studies must have measured smoking cessation at four weeks or longer.

**Data collection and analysis**
Two review authors independently assessed and extracted data. We extracted and, where appropriate, pooled smoking cessation outcomes of six‐month follow‐up or more, reporting short‐term outcomes narratively where longer‐term outcomes were not available. We reported study effects as a risk ratio (RR) with a 95% confidence interval (CI).

We grouped studies according to whether they (1) compared an Internet intervention with a non‐active control arm (e.g. printed self‐help guides), (2) compared an Internet intervention with an active control arm (e.g. face‐to‐face counselling), (3) evaluated the addition of behavioural support to an Internet programme, or (4) compared one Internet intervention with another. Where appropriate we grouped studies by age.

**Main results**
We identified 67 RCTs, including data from over 110,000 participants. We pooled data from 35,969 participants.

There were only four RCTs conducted in adolescence or young adults that were eligible for meta‐analysis.

Results for trials in adults: Eight trials compared a tailored and interactive Internet intervention to a non‐active control. Pooled results demonstrated an effect in favour of the intervention (RR 1.15, 95% CI 1.01 to 1.30, n = 6786). However, statistical heterogeneity was high (I2 = 58%) and was unexplained, and the overall quality of evidence was low according to GRADE. Five trials compared an Internet intervention to an active control. The pooled effect estimate favoured the control group, but crossed the null (RR 0.92, 95% CI 0.78 to 1.09, n = 3806, I2 = 0%); GRADE quality rating was moderate. Five studies evaluated an Internet programme plus behavioural support compared to a non‐active control (n = 2334). Pooled, these studies indicated a positive effect of the intervention (RR 1.69, 95% CI 1.30 to 2.18). Although statistical heterogeneity was substantial (I2 = 60%) and was unexplained, the GRADE rating was moderate. Four studies evaluated the Internet plus behavioural support compared to active control. None of the studies detected a difference between trial arms (RR 1.00, 95% CI 0.84 to 1.18, n = 2769, I2 = 0%); GRADE rating was moderate. Seven studies compared an interactive or tailored Internet intervention, or both, to an Internet intervention that was not tailored/interactive. Pooled results favoured the interactive or tailored programme, but the estimate crossed the null (RR 1.10, 95% CI 0.99 to 1.22, n = 14,623, I2 = 0%); GRADE rating was moderate. Three studies compared tailored with non‐tailored Internet‐based messages, compared to non‐tailored messages. The tailored messages produced higher cessation rates compared to control, but the estimate was not precise (RR 1.17, 95% CI 0.97 to 1.41, n = 4040), and there was evidence of unexplained substantial statistical heterogeneity (I2 = 57%); GRADE rating was low.

Results should be interpreted with caution as we judged some of the included studies to be at high risk of bias.

**Authors&#039; conclusions**
The evidence from trials in adults suggests that interactive and tailored Internet‐based interventions with or without additional behavioural support are moderately more effective than non‐active controls at six months or longer, but there was no evidence that these interventions were better than other active smoking treatments. However some of the studies were at high risk of bias, and there was evidence of substantial statistical heterogeneity. Treatment effectiveness in younger people is unknown.
AU  - Taylor,
AU  - G.
AU  - Dalili,
AU  - M.
AU  - Semwal,
AU  - M.
AU  - Civljak,
AU  - M.
AU  - Sheikh,
AU  - A.
AU  - Car,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD007078.pub5
PY  - 2017
TI  - Internet‐based interventions for smoking cessation
ER  -
TY  - JOUR
AB  - **Background**
Depression is a highly prevalent mood disorder that is characterised by persistent low mood, diminished interest, and loss of pleasure. Music therapy may be helpful in modulating moods and emotions. An update of the 2008 Cochrane review was needed to improve knowledge on effects of music therapy for depression.

**Objectives**
1. To assess effects of music therapy for depression in people of any age compared with treatment as usual (TAU) and psychological, pharmacological, and/or other therapies.

2. To compare effects of different forms of music therapy for people of any age with a diagnosis of depression.

**Search methods**
We searched the following databases: the Cochrane Common Mental Disorders Controlled Trials Register (CCMD‐CTR; from inception to 6 May 2016); the Cochrane Central Register of Controlled Trials (CENTRAL; to 17 June 2016); Thomson Reuters/Web of Science (to 21 June 2016); Ebsco/PsycInfo, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase, and PubMed (to 5 July 2016); the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP), ClinicalTrials.gov, the National Guideline Clearing House, and OpenGrey (to 6 September 2016); and the Digital Access to Research Theses (DART)‐Europe E‐theses Portal, Open Access Theses and Dissertations, and ProQuest Dissertations and Theses Database (to 7 September 2016). We checked reference lists of retrieved articles and relevant systematic reviews and contacted trialists and subject experts for additional information when needed. We updated this search in August 2017 and placed potentially relevant studies in the &quot;Awaiting classification&quot; section; we will incorporate these into the next version of this review as appropriate.

**Selection criteria**
All randomised controlled trials (RCTs) and controlled clinical trials (CCTs) comparing music therapy versus treatment as usual (TAU), psychological therapies, pharmacological therapies, other therapies, or different forms of music therapy for reducing depression.

**Data collection and analysis**
Two review authors independently selected studies, assessed risk of bias, and extracted data from all included studies. We calculated standardised mean difference (SMD) for continuous data and odds ratio (OR) for dichotomous data with 95% confidence intervals (CIs). We assessed heterogeneity using the I2 statistic.

**Main results**
We included in this review nine studies involving a total of 421 participants, 411 of whom were included in the meta‐analysis examining short‐term effects of music therapy for depression. Concerning primary outcomes, we found moderate‐quality evidence of large effects favouring music therapy and TAU over TAU alone for both clinician‐rated depressive symptoms (SMD ‐0.98, 95% CI ‐1.69 to ‐0.27, 3 RCTs, 1 CCT, n = 219) and patient‐reported depressive symptoms (SMD ‐0.85, 95% CI ‐1.37 to ‐0.34, 3 RCTs, 1 CCT, n = 142). Music therapy was not associated with more or fewer adverse events than TAU. Regarding secondary outcomes, music therapy plus TAU was superior to TAU alone for anxiety and functioning. Music therapy and TAU was not more effective than TAU alone for improved quality of life (SMD 0.32, 95% CI ‐0.17 to 0.80, P = 0.20, n = 67, low‐quality evidence). We found no significant discrepancies in the numbers of participants who left the study early (OR 0.49, 95% CI 0.14 to 1.70, P = 0.26, 5 RCTs, 1 CCT, n = 293, moderate‐quality evidence). Findings of the present meta‐analysis indicate that music therapy added to TAU provides short‐term beneficial effects for people with depression if compared to TAU alone. Additionally, we are uncertain about the effects of music therapy versus psychological therapies on clinician‐rated depression (SMD ‐0.78, 95% CI ‐2.36 to 0.81, 1 RCT, n = 11, very low‐quality evidence), patient‐reported depressive symptoms (SMD ‐1.28, 95% CI ‐3.75 to 1.02, 4 RCTs, n = 131, low‐quality evidence), quality of life (SMD ‐1.31, 95% CI ‐ 0.36 to 2.99, 1 RCT, n = 11, very low‐quality evidence), and leaving the study early (OR 0.17, 95% CI 0.02 to 1.49, 4 RCTs, n = 157, moderate‐quality evidence). We found no eligible evidence addressing adverse events, functioning, and anxiety. We do not know whether one form of music therapy is better than another for clinician‐rated depressive symptoms (SMD ‐0.52, 95% CI ‐1.87 to 0.83, 1 RCT, n = 9, very low‐quality evidence), patient‐reported depressive symptoms (SMD ‐0.01, 95% CI ‐1.33 to 1.30, 1 RCT, n = 9, very low‐quality evidence), quality of life (SMD ‐0.24, 95% CI ‐1.57 to 1.08, 1 RCT, n = 9, very low‐quality evidence), or leaving the study early (OR 0.27, 95% CI 0.01 to 8.46, 1 RCT, n = 10). We found no eligible evidence addressing adverse events, functioning, or anxiety.

**Authors&#039; conclusions**
Findings of the present meta‐analysis indicate that music therapy provides short‐term beneficial effects for people with depression. Music therapy added to treatment as usual (TAU) seems to improve depressive symptoms compared with TAU alone. Additionally, music therapy plus TAU is not associated with more or fewer adverse events than TAU alone. Music therapy also shows efficacy in decreasing anxiety levels and improving functioning of depressed individuals.

Future trials based on adequate design and larger samples of children and adolescents are needed to consolidate our findings. Researchers should consider investigating mechanisms of music therapy for depression. It is important to clearly describe music therapy, TAU, the comparator condition, and the profession of the person who delivers the intervention, for reproducibility and comparison purposes.
AN  - WOS:000416982300001
AU  - Aalbers,
AU  - S.
AU  - Fusar-Poli,
AU  - L.
AU  - Freeman,
AU  - R.
AU  - E.
AU  - Spreen,
AU  - M.
AU  - Ket,
AU  - J.
AU  - C.
AU  - F.
AU  - Vink,
AU  - A.
AU  - C.
AU  - Maratos,
AU  - A.
AU  - Crawford,
AU  - M.
AU  - Chen,
AU  - X.
AU  - J.
AU  - Gold,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD004517.pub3
L1  - internal-pdf://1994497950/Aalbers-2017-Music therapy for depression.pdf
PY  - 2017
SP  - 103
T2  - Cochrane Database of Systematic Reviews
TI  - Music therapy for depression
UR  - &lt;Go to ISI&gt;://WOS:000416982300001
UR  - http://onlinelibrary.wiley.com/store/10.1002/14651858.CD004517.pub3/asset/CD004517.pdf?v=1&amp;t=je6ubj4i&amp;s=006b80b92ba176920513e57a25c52cb8b74c8fb1
ER  -
TY  - JOUR
AB  - Anxiety disorders are among the most common disorders affecting youths in the general population, with up to 10% of children and 20% of adolescents meeting criteria for an anxiety disorder at any one point in time. 

Cognitive-behavior therapies (CBT), varying between 9 and 18 weeks of treatment, are considered evidence-based for the treatment of anxiety disorders in youth. During the last two decades treatments that are brief, intensive, or concentrated (BIC) have been developed and this meta-analysis includes 23 RCTs of these new approaches across the anxiety disorders. BIC yielded a lower attrition (2.3%) than standard CBT (6.5%). The effect sizes (ES) for comparison of BIC with waiting-list (1.47) and placebo (0.91) were significant, whereas that with standard CBT (0.01) was not. 

Regarding remission at post/recovery at follow-up BIC (54%/64%) and standard CBT (57%/63%) were comparable and both were significantly higher than placebo (26%/35%), which was higher than WLC (7%/9%). Within-group ES at post and follow-up were 1.50 and 1.53 for BIC, and 0.98 and 1.05 for standard CBT, indicating maintenance of the effects up to 12 months after therapy. 

Advantages and disadvantages of BIC are discussed and we suggest that BIC-interventions represent a paradigm shift in the delivery of services for youth with anxiety disorders. 

Copyright &copy; 2017 Elsevier Ltd
AN  - 617557247
AU  - Ost,
AU  - L.
AU  - G.
AU  - Ollendick,
AU  - T.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.brat.2017.07.008
L1  - internal-pdf://3052553129/Ost-2017-Brief, intensive and concentrated cog.pdf
PY  - 2017
SP  - 134-145
TI  - Brief, intensive and concentrated cognitive behavioral treatments for anxiety disorders in children: A systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/brat
VL  - 97
ER  -
TY  - JOUR
AB  - This article reviews the state of the science on psychosocial treatments for disruptive behaviors in children, as an update to Eyberg, Nelson, and Boggs (2008). 

We followed procedures for literature searching, study inclusion, and treatment classification as laid out in Southam-Gerow and Prinstein (2014), focusing on treatments for children 12 years of age and younger. 

Two treatments (group parent behavior therapy, and individual parent behavior therapy with child participation) had sufficient empirical support to be classified as well-established treatments. 

Thirteen other treatments were classified as probably efficacious. Substantial variability in effectiveness of different programs within the same treatment family has been previously documented; thus, a particular level of evidence might not hold true for every individual program in a treatment family. 

Systematic investigations of implementation, dissemination, and uptake are needed to ensure that children and families have access to effective treatments. Investigations into how to blend the strengths of the effective approaches into even more effective treatment might also lead to greater impact.
AD  - Kaminski, Jennifer W. a National Center on Birth Defects and Developmental Disabilities , Centers for Disease Control and Prevention.Claussen, Angelika H. a National Center on Birth Defects and Developmental Disabilities , Centers for Disease Control and Prevention.
AN  - 28459280
AU  - Kaminski,
AU  - J.
AU  - W.
AU  - Claussen,
AU  - A.
AU  - H.
DA  - Jul-Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15374416.2017.1310044
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
KW  - Adolescent
KW  - Child
KW  - Child, Preschool
KW  - *Evidence-Based Medicine/mt [Methods]
KW  - Humans
KW  - Male
KW  - *Problem Behavior/px [Psychology]
KW  - *Psychotherapy/mt [Methods]
KW  - Treatment Outcome
L1  - internal-pdf://2461125605/kaminski.pdf
LA  - English
M3  - Review
N1  - Kaminski, Jennifer WClaussen, Angelika H
PY  - 2017
SP  - 477-499
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Evidence Base Update for Psychosocial Treatments for Disruptive Behaviors in Children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=28459280
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28459280&amp;id=doi:10.1080%2F15374416.2017.1310044&amp;issn=1537-4416&amp;isbn=&amp;volume=46&amp;issue=4&amp;spage=477&amp;pages=477-499&amp;date=2017&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Evidence+Base+Update+for+Psychosocial+Treatments+for+Disruptive+Behaviors+in+Children.&amp;aulast=Kaminski&amp;pid=%3Cauthor%3EKaminski+JW%3C%2Fauthor%3E%3CAN%3E28459280%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 46
ER  -
TY  - JOUR
AB  - The daily report card (DRC) is a commonly employed behavioral intervention for treating attention deficit hyperactivity disorder (ADHD) in schools. 

Much of the support for the DRC comes from single-case studies, which have traditionally received less attention than group studies. This lack of attention to single-case studies results in an incomplete review of the literature for this intervention. 

The present study utilized meta-analytic techniques to examine the DRC as used in single-case studies, with moderating variables explored through hierarchical linear modeling. 

Fourteen articles, including data on 40 single-subject cases, were included in the analyses. Effect sizes generally illustrated improvement with use of the DRC, with some differences across methods of effect size estimation. 

Study quality and class type moderated outcomes. Overall, the present study supports the use of the DRC with students who have ADHD, and it provides guidance for using single-case studies in meta-analyses of intervention effects.
AN  - WOS:000407518600004
AU  - Pyle,
AU  - K.
AU  - Fabiano,
AU  - G.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0014402917706370
L1  - internal-pdf://0896969647/Pyle-2017-Daily Report Card Intervention and A.pdf
PY  - 2017
SP  - 378-395
TI  - Daily Report Card Intervention and Attention Deficit Hyperactivity Disorder: A Meta-Analysis of Single-Case Studies
UR  - &lt;Go to ISI&gt;://WOS:000407518600004
VL  - 83
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
Comparative efficacy and safety are important issues for appropriate drug selection for attention-deficit hyperactivity disorder (ADHD) treatment. Therefore we conducted a meta-analysis, where we compared atomoxetine (ATX) and methylphenidate (MPH) for ADHD treatment in children and adolescents. 

**METHOD: **
Literature retrieval was conducted in relevant databases from their inception to April 2016 to select head-to-head trials that compared ATX and MPH in children and adolescents. Outcomes like response rate, ADHD Rating Scale (ADHD-RS) score, and adverse events were compared between ATX and MPH treatments. The standardized mean difference (SMD) and risk ratio (RR) with their corresponding 95% confidence intervals (CIs) were used as the effect size for continuous data or dichotomous data, respectively. 

**RESULTS: **
Eleven eligible randomized-controlled trials were included, and two of them were double-blind, while the remaining were open-label. Compared to ATX, MPH showed a higher response rate (RR = 1.14, 95% CI [1. 09, 1.20]), decreased inattention (SMD = -0.13, 95% CI [-0.25, -0.01]) and lower risk of adverse events (drowsiness: RR = 0.17, 95% CI [0.11, 0.26; nausea: RR = 0.49; 95% CI [0.29, 0.85; vomiting: RR = 0.41, 95% CI [0.27, 0.63]). However, MPH presented a higher risk of insomnia than ATX (RR = 2.27, 95% CI [1.63, 3.15], p &lt; .01). 

**CONCLUSION: **
Results of the meta-analysis add additional evidence of the effectiveness of both ATX and MPH and suggest that MPH should be a first treatment option in most patients with ADHD.
AD  - Liu, Qiang. a Pediatrics Department , Shandong Provincial Hospital Affiliated to Shandong University, Shandong University , Jinan , China. Liu, Qiang. b Newborn Department , Linyi People&#039;s Hospital , Linyi , China. Zhang, Hong. c Department of Pediatrics , Linyi Traditional Chinese Medical Hospital , Linyi , China. Fang, Qingqing. d Department of Pediatrics , The People&#039;s Hospital of Lanshan District , LinYi , China. Qin, Lili. e Department of Pediatrics , Weishan County People&#039;s Hospital , Jining , China.
AN  - 28052720
AU  - Liu,
AU  - Q.
AU  - Zhang,
AU  - H.
AU  - Fang,
AU  - Q.
AU  - Qin,
AU  - L.
DA  - Jan 04
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/13803395.2016.1273320
DP  - Ovid Technologies
J2  - J Clin Exp Neuropsychol
L1  - internal-pdf://0853690226/Comparative efficacy and safety of methylpheni.pdf
LA  - English
N1  - Liu, Qiang Zhang, Hong Fang, Qingqing Qin, Lili
PY  - 2017
SP  - 1-12
T2  - Journal of Clinical and Experimental Neuropsychology
TI  - Comparative efficacy and safety of methylphenidate and atomoxetine for attention-deficit hyperactivity disorder in children and adolescents: Meta-analysis based on head-to-head trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28052720http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28052720&amp;id=doi:10.1080%2F13803395.2016.1273320&amp;issn=1380-3395&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-12&amp;date=2017&amp;title=Journal+of+Clinical+%26+Experimental+Neuropsychology%3A+Official+Journal+of+the+International+Neuropsychological+Society&amp;atitle=Comparative+efficacy+and+safety+of+methylphenidate+and+atomoxetine+for+attention-deficit+hyperactivity+disorder+in+children+and+adolescents%3A+Meta-analysis+based+on+head-to-head+trials.&amp;aulast=Liu&amp;pid=%3Cauthor%3ELiu+Q%3C%2Fauthor%3E%3CAN%3E28052720%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - Mental wellbeing is influenced by self-regulation processes. However, little is known on the efficacy of change techniques based on self-regulation to promote mental wellbeing. The aim of this meta-analysis is to identify effective self-regulation techniques (SRTs) in primary and secondary prevention interventions on mental wellbeing in adolescents. Forty interventions were included in the analyses. Techniques were coded into nine categories of SRTs. 

Meta-analyses were conducted to identify the effectiveness of SRTs, examining three different outcomes: internalising behaviour, externalising behaviour, and self-esteem. Primary interventions had a small-to-medium ([Formula: see text]=0.16-0.29) on self-esteem and internalising behaviour. Secondary interventions had a medium-to-large short-term effect (average [Formula: see text]=0.56) on internalising behaviour and self-esteem. In secondary interventions, interventions including asking for social support [Formula: see text] 95% confidence interval, CI=1.11-1.98) had a great effect on internalising behaviour. 

Interventions including monitoring and evaluation had a greater effect on self-esteem [Formula: see text] 95% CI=0.21-0.57). For primary interventions, there was not a single SRT that was associated with a greater intervention effect on internalising behaviour or self-esteem. No effects were found for externalising behaviours. Self-regulation interventions are moderately effective at improving mental wellbeing among adolescents. 

Secondary interventions promoting &#039;asking for social support&#039; and promoting &#039;monitoring and evaluation&#039; were associated with improved outcomes. More research is needed to identify other SRTs or combinations of SRTs that could improve understanding or optimise mental wellbeing interventions.
AD  - van Genugten, Lenneke. a Department of Public Health , Erasmus MC, University Medical Centre Rotterdam , Rotterdam , The Netherlands. van Genugten, Lenneke. b Expertise Group Life Style , Netherlands Organization for Applied Scientific Research (TNO) , Leiden , The Netherlands. Dusseldorp, Elise. b Expertise Group Life Style , Netherlands Organization for Applied Scientific Research (TNO) , Leiden , The Netherlands. Dusseldorp, Elise. d Institute of Psychology, Methodology &amp; Statistics, Leiden University , Leiden , The Netherlands. Massey, Emma K. c Department of Internal Medicine, Section Nephrology &amp; Transplantation , Erasmus MC, University Medical Centre Rotterdam , Rotterdam , The Netherlands. van Empelen, Pepijn. b Expertise Group Life Style , Netherlands Organization for Applied Scientific Research (TNO) , Leiden , The Netherlands.
AN  - 27796160
AU  - van
AU  - Genugten,
AU  - L.
AU  - Dusseldorp,
AU  - E.
AU  - Massey,
AU  - E.
AU  - K.
AU  - van
AU  - Empelen,
AU  - P.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/17437199.2016.1252934
DP  - Ovid Technologies
J2  - Health psychol
L1  - internal-pdf://1060953620/Effective self regulation change techniques to.pdf
LA  - English
N1  - van Genugten, Lenneke Dusseldorp, Elise Massey, Emma K van Empelen, Pepijn
PY  - 2017
SP  - 53-71
T2  - Health Psychology Review
TI  - Effective self-regulation change techniques to promote mental wellbeing among adolescents: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27796160http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27796160&amp;id=doi:10.1080%2F17437199.2016.1252934&amp;issn=1743-7199&amp;isbn=&amp;volume=11&amp;issue=1&amp;spage=53&amp;pages=53-71&amp;date=2017&amp;title=Health+Psychology+Review&amp;atitle=Effective+self-regulation+change+techniques+to+promote+mental+wellbeing+among+adolescents%3A+a+meta-analysis.&amp;aulast=van+Genugten&amp;pid=%3Cauthor%3Evan+Genugten+L%3C%2Fauthor%3E%3CAN%3E27796160%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 11
ER  -
TY  - JOUR
AB  - BACKGROUND: 
There has been increased interest in early screening and intervention for young children with, or at risk of, autism spectrum disorder (ASD). This has generated a debate about the potential harms versus benefits of early identification and treatment. This review aims to identify the evidence base for early intervention in ASD. 

METHODS: 
A systematic review searching for randomised controlled trials (RCTs) of interventions for children up to 6 years of age with, or at risk of, ASD was undertaken. Characteristics and outcomes of included studies were collated and described in tabular format, and all included studies were rated according to the Cochrane Risk of Bias Tool.

RESULTS: 
Forty-eight RCTs were identified, of which 40 were published since 2010. Most studies (n = 34) were undertaken in the United States. Included RCTs evaluated 32 different models of intervention. If blinding of participants and relevant personnel is overlooked as a source of bias, only six studies met criteria for low risk of bias across all domains of the Cochrane Risk of Bias Tool. The majority of studies had a relatively small sample size with only seven studies having a sample size &gt;100. 

CONCLUSIONS: 
There has been a substantial increase in the number of RCTs evaluating early interventions in ASD. However, few studies, only 12.5% of the total, were rated as being at low risk of bias. Small sample size, unclear concealment of allocation and lack of clarity in the identification of the active ingredients in a diverse range of differently named treatment models were identified as challenges to the design, conduct and interpretation of studies. Improved co-ordination and design of studies is, therefore, required if future research in the field is to more clearly investigate the effects of early intervention for ASD.
AN  - 29052838
AU  - French,
AU  - L.
AU  - Kennedy,
AU  - E.
AU  - M.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.12828
L1  - internal-pdf://1745315008/French-2017-Research Review_ Early interventio.pdf
PY  - 2017
SP  - 20
TI  - Research Review: Early intervention for infants and young children with, or at-risk of, autism spectrum disorder: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29052838
VL  - 20
ER  -
TY  - JOUR
AB  - **Background**
The United Nations reported that in 2016 over 65 million people worldwide have forcibly left home. Over 50% are children and adolescents; a substantial number has been traumatized and displaced by war. 

**Objective**
To provide an overview of the effectiveness of psychosocial interventions in this group we conducted a narrative review and a meta-analysis of intervention studies providing data on posttraumatic stress symptoms (PTSS), depression, anxiety, grief, and general distress. 

**Method**
We searched PILOTS, MEDLINE, WoS, Embase, CENTRAL, LILACS, PsycINFO, ASSIA, CSA, and SA for studies on treatment outcomes for war-traumatized displaced children and adolescents. Between-group effect sizes (ES) and pre-post ES were reconstructed for each trial. Overall pre-post ES were calculated using a random effects model. 

**Results** 
The narrative review covers 23 studies with a variety of treatments. Out of the 35 calculated between-group ES, only six were significant, all compared to untreated controls. Two of them indicated significant adverse effects on symptoms of general distress or depression. When calculating pre-post effect sizes, the positive between-group results of cognitive behavioural therapy (CBT) and interpersonal therapy (IPT) were reproduced and singular other treatments showed significant positive effects. However, the mean pre-post effects for PTSS and depression could not be interpreted due to the high heterogeneity of the included studies (PTSS: ES = 0.78; I&lt;sup&gt;2&lt;/sup&gt; = 88.6%; depression: ES = 0.35; I&lt;sup&gt;2&lt;/sup&gt; = 93.1%). Only the mean pre-post effect for seven active CBT treatment groups for depression (ES = 0.30, 95% CI [0.18, 0.43]) was interpretable (Q = 3.3, df = 6, p = .77). 

**Conclusion**
Given the large number of children and adolescents displaced by war there were regrettably few treatment studies available, and many of them were of low methodological quality. The effect sizes lagged behind the effects observed in traumatized minors in general, and often were small or non-significant. However, CBT and IPT showed promising results that need further replication.
AN  - 29163868
AU  - Nocon,
AU  - A.
AU  - Eberle-Sejari,
AU  - R.
AU  - Unterhitzenberger,
AU  - J.
AU  - Rosner,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/20008198.2017.1388709
L1  - internal-pdf://1114572817/Nocon-2017-The effectiveness of psychosocial i.pdf
PY  - 2017
SP  - 1388709
T2  - European Journal of Psychotraumatology
TI  - The effectiveness of psychosocial interventions in war-traumatized refugee and internally displaced minors: systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29163868
VL  - 8
ER  -
TY  - JOUR
AB  - **Importance: **
Depressive disorders (DDs), anxiety disorders (ADs), obsessive-compulsive disorder (OCD), and posttraumatic stress disorder (PTSD) are common mental disorders in children and adolescents. 

**Objective: **
To examine the relative efficacy and safety of selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and placebo for the treatment of DD, AD, OCD, and PTSD in children and adolescents. 

**Data Sources: **
PubMed, EMBASE, PsycINFO, Web of Science, and Cochrane Database from inception through August 7, 2016.

**Study Selection: **
Published and unpublished randomized clinical trials of SSRIs or SNRIs in youths with DD, AD, OCD, or PTSD were included. Trials using other antidepressants (eg, tricyclic antidepressants, monoamine oxidase inhibitors) were excluded.

**Data Extraction and Synthesis: **
Effect sizes, calculated as standardized mean differences (Hedges g) and risk ratios (RRs) for adverse events, were assessed in a random-effects model. 

**Main Outcomes and Measures:**
Primary outcomes, as defined by authors on preintervention and postintervention data, mean change data, and adverse event data, were extracted independently by multiple observers following PRISMA guidelines. 

**Results: **
Thirty-six trials were eligible, including 6778 participants (3484 [51.4%] female; mean [SD] age, 12.9 [5.1] years); 17 studies for DD, 10 for AD, 8 for OCD, and 1 for PTSD. Analysis showed that SSRIs and SNRIs were significantly more beneficial compared with placebo, yielding a small effect size (g=0.32; 95% CI, 0.25-0.40; P&lt;.001). Anxiety disorder (g=0.56; 95% CI, 0.40-0.72; P&lt;.001) showed significantly larger between-group effect sizes than DD (g=0.20; 95% CI, 0.13-0.27; P&lt;.001). This difference was driven primarily by the placebo response: patients with DD exhibited significantly larger placebo responses (g=1.57; 95% CI, 1.36-1.78; P&lt;.001) compared with those with AD (g=1.03; 95% CI, 0.84-1.21; P&lt;.001). The SSRIs produced a relatively large effect size for ADs (g=0.71; 95% CI, 0.45-0.97; P&lt;.001). Compared with participants receiving placebo, patients receiving an antidepressant reported significantly more treatment-emergent adverse events (RR, 1.07; 95% CI, 1.01-1.12; P=.01 or RR, 1.49; 95% CI, 1.22-1.82; P&lt;.001, depending on the reporting method), severe adverse events (RR, 1.76; 95% CI, 1.34-2.32; P&lt;.001), and study discontinuation due to adverse events (RR, 1.79; 95% CI, 1.38-2.32; P&lt;.001). 

**Conclusions and Relevance: **
Compared with placebo, SSRIs and SNRIs are more beneficial than placebo in children and adolescents; however, the benefit is small and disorder specific, yielding a larger drug-placebo difference for AD than for other conditions. Response to placebo is large, especially in DD. Severe adverse events are significantly more common with SSRIs and SNRIs than placebo.
AN  - 28854296
AU  - Locher,
AU  - C.
AU  - Koechlin,
AU  - H.
AU  - Zion,
AU  - S.
AU  - R.
AU  - Werner,
AU  - C.
AU  - Pine,
AU  - D.
AU  - S.
AU  - Kirsch,
AU  - I.
AU  - Kessler,
AU  - R.
AU  - C.
AU  - Kossowsky,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1001/jamapsychiatry.2017.2432
L1  - internal-pdf://3100576494/Locher-2017-Efficacy and Safety of Selective S.pdf
PY  - 2017
SP  - 30
TI  - Efficacy and Safety of Selective Serotonin Reuptake Inhibitors, Serotonin-Norepinephrine Reuptake Inhibitors, and Placebo for Common Psychiatric Disorders Among Children and Adolescents: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28854296
VL  - 30
ER  -
TY  - JOUR
AB  - Parenting interventions are known to reduce disruptive child behavior immediately post intervention. But it is largely unknown how reduced disruptive behavior develops in the months and years after the intervention. 

The present systematic review and multilevel meta-analysis examines whether improvements in disruptive child behavior after parenting intervention are maintained (i.e., sustained effects), fall back (i.e., fade-out effects), or increase further (i.e., sleeper effects). 

We identified 40 randomized controlled trials with follow-up assessments (up to three years) that generated 91 effect sizes. Mean effect size of post-intervention change was d = 0.01, 95% CI [-0.05, 0.07], p = 0.78. This lack of change suggests that parenting interventions lead to sustained effects on disruptive behavior. However, there was heterogeneity within and between trials, indicating that some interventions, or interventions under certain circumstances do show fade-out or sleeper effects. 

None of the moderators tested (i.e., length of follow-up and initial intervention success) explained this heterogeneity. We conclude that parenting interventions generally lead to sustained reductions in disruptive child behavior, at least until three year after intervention. Better understanding is needed of when and why sustainability is stronger in some cases than in others. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AD  - van Aar, Jolien: J.vanAar@uva.nl van Aar, Jolien: Research Institute of Child Development and Education, University of Amsterdam, Nieuwe Achtergracht 127, Amsterdam, Netherlands, 1018 WS, J.vanAar@uva.nl van Aar, Jolien: University of Amsterdam, Amsterdam, Netherlands Leijten, Patty: University of Amsterdam, Amsterdam, Netherlands Orobio de Castro, Bram: Utrecht University, Utrecht, Netherlands Overbeek, Geertjan: University of Amsterdam, Amsterdam, Netherlands
AN  - 2016-62331-012
AU  - van
AU  - Aar,
AU  - J.
AU  - Leijten,
AU  - P.
AU  - Orobio
AU  - de
AU  - Castro,
AU  - B.
AU  - Overbeek,
AU  - G.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2016.11.006
DP  - Ovid Technologies
KW  - Parenting intervention, Disruptive child behavior, Meta-analysis, Follow-up effects, Longer term effects
KW  - *Behavior Problems
KW  - *Intervention
KW  - *Parent Training
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
L1  - internal-pdf://2474892054/van-2017-Sustained, fade-out or sleeper effect.pdf
LA  - English
M3  - Meta Analysis
PY  - 2017
SP  - 153-163
T2  - Clinical Psychology Review
TI  - Sustained, fade-out or sleeper effects? A systematic review and meta-analysis of parenting interventions for disruptive child behavior
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-62331-012http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.cpr.2016.11.006&amp;issn=0272-7358&amp;isbn=&amp;volume=51&amp;issue=&amp;spage=153&amp;pages=153-163&amp;date=2017&amp;title=Clinical+Psychology+Review&amp;atitle=Sustained%2C+fade-out+or+sleeper+effects%3F+A+systematic+review+and+meta-analysis+of+parenting+interventions+for+disruptive+child+behavior.&amp;aulast=van+Aar&amp;pid=%3Cauthor%3Evan+Aar%2C+Jolien%3C%2Fauthor%3E%3CAN%3E2016-62331-012%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0272735816301891/1-s2.0-S0272735816301891-main.pdf?_tid=25727ef8-04d1-11e7-aefe-00000aab0f6c&amp;acdnat=1489068378_75c2b4608b09b7a4163b643887e0041a
VL  - 51
ER  -
TY  - JOUR
AB  - Depression and anxiety disorders are among the most common mental disorders during adolescence. During this life phase, the incidence of these clinical disorders rises dramatically, and even more adolescents suffer from symptoms of depression or anxiety that are just below the clinical threshold. 

Both clinical and subclinical levels of depression or anxiety symptoms are related to decreased functioning in various areas, such as social and academic functioning. Prevention of depression and anxiety in adolescents is therefore imperative. We conducted a meta-analytic review of the effects of school-based and community-based prevention programs that are based on cognitive behavioral therapy with the primary goal preventing depression, anxiety, or both in high risk adolescents. 

Articles were obtained by searching databases and hand searching reference lists of relevant articles and reviews. The selection process yielded 32 articles in the meta-analyses. One article reported on two studies and three articles reported on both depression and anxiety. 

This resulted in a total of 36 studies, 23 on depression and 13 on anxiety. For depression prevention aimed at high risk adolescents, meta-analysis showed a small effect of prevention programs directly after the intervention, but no effect at 3-6 months and at 12 months follow-up. For anxiety prevention aimed at high risk adolescents, no short-term effect was found, nor at 12 months follow-up. Three to six months after the preventive intervention, symptoms of anxiety were significantly decreased. 

Although effects on depression and anxiety symptoms were small and temporary, current findings cautiously suggest that depression and anxiety prevention programs based on CBT might have small effects on mental health of adolescents. However, it also indicates that there is still much to be gained for prevention programs. 

Current findings and possibilities for future research are discussed in order to further improve the effectiveness of targeted prevention on internalizing disorders.
AN  - 28701980
AU  - Rasing,
AU  - S.
AU  - P.
AU  - A.
AU  - Creemers,
AU  - D.
AU  - H.
AU  - M.
AU  - Janssens,
AU  - J.
AU  - Scholte,
AU  - R.
AU  - H.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3389/fpsyg.2017.01066
L1  - internal-pdf://0630844955/Rasing-2017-Depression and Anxiety Prevention.pdf
PY  - 2017
SP  - 1066
TI  - Depression and Anxiety Prevention Based on Cognitive Behavioral Therapy for At-Risk Adolescents: A Meta-Analytic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28701980
VL  - 8
ER  -
TY  - JOUR
AB  - **Purpose: **
To perform a systematic review of the research relating to the outcomes of speech-language pathology (SLP) intervention for children who have suffered maltreatment and are in Out Of Home Care. 

**Method: **
A search was performed of 10 electronic databases to identify studies which addressed two research questions. Structured review procedures were used to select and evaluate research studies.

**Results: **
No studies met the review criteria, although some informal articles provided insight into potential ways to support children who had suffered maltreatment. 

**Conclusions: **
While there is a growing body of evidence that identifies an increasing number of children who have suffered maltreatment and are at high risk of communication impairment, there is a significant gap in the SLP research literature relating to the investigation of the outcomes of communication intervention for this cohort. 

(PsycINFO Database Record (c) 2018 APA, all rights reserved)
AD  - Byrne, Nicole: nicole.byrne@newcastle.edu.au
AN  - 2018-07425-006
AU  - Byrne,
AU  - N.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
L1  - internal-pdf://2318199461/Byrne-2017-Systematic review of speech and lan.pdf
PY  - 2017
SP  - 57-61
T2  - Speech, Language and Hearing
TI  - Systematic review of speech and language therapy outcomes for children who are in Out of Home Care (OOHC)
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2018-07425-006
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F2050571X.2016.1207399&amp;issn=2050-571X&amp;isbn=&amp;volume=20&amp;issue=1&amp;spage=57&amp;pages=57-61&amp;date=2017&amp;title=Speech%2C+Language+and+Hearing&amp;atitle=Systematic+review+of+speech+and+language+therapy+outcomes+for+children+who+are+in+Out+of+Home+Care+%28OOHC%29.&amp;aulast=Byrne&amp;pid=%3Cauthor%3EByrne%2C+Nicole%3C%2Fauthor%3E%3CAN%3E2018-07425-006%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 20
ER  -
TY  - JOUR
AB  - Bakgrunn
Artikkelen er en kunnskapsoppsummering for effektene av tiltaket Aggression Replacement Training (ART&reg;). Dette er en revisjon av en tidligere utgave av det samme tiltaket som ble beskrevet i Ungsinn (Kjøbli, 2009), men oppdatert i forhold til Ungsinns nye prosedyrer og kriterier (Martinussen et al., 2016). Denne artikkelen inkluderer også den tilpassede skandinaviske versjonen Adapted Aggression Replacement Training (AART). ART/AART er et strukturert pedagogisk multimodalt gruppeprogram for trening av sosial kompetanse hos barn og unge. Tiltaket består av tre komponenter; sosial ferdighetstrening, sinnekontroll og moralsk resonnering. Målet med ART/AART er å øke barn og unges sosiale ferdigheter som kan erstatte aggresjon. Gjennomføringen av tiltaket anbefales å gå over 30 timer der hver av de tre komponentene gjennomgås en gang per uke, fortrinnsvis i et eget ART-rom. Gruppene består av 4-8 deltagere, og utføres av en hovedtrener og en medtrener.

Metode
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS og SweMed. Syv artikler, derav tre nordiske effektstudier, en internasjonal oppsummeringsstudie og tre andre norske studier ble inkludert i denne kunnskapsoppsummeringen av ART.

Resultater
Resultatene består av en vurdering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. ART/AART har et grundig teoretisk fundament og tiltaket er godt beskrevet med anbefalte implementeringsstrategier. Det foreligger tre nordiske studier der effekten av ARTer undersøkt. Disse studiene har alle et kvasi-eksperimentelt design. Svak forskningsmetodisk kvalitet skaper imidlertid usikkerhet om påliteligheten til resultatene. Det foreligger ingen studier på AART på nåværende tidspunkt.

Konklusjon
ART/AART klassifiseres på evidensnivå 3 &ndash; Tiltak med noe dokumentasjon på effekt.
AU  - Rasmussen,
AU  - L-M.
AU  - P.,
AU  - Strøm,
AU  - H.
AU  - K.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2017
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: ART &ndash; Aggression Replacement Training/Adapted Aggression Replacement Training (AART) (2. utg)
UR  - https://ungsinn.no/post_tiltak_arkiv/kunnskapsoppsummering-og-klassifisering-av-tiltaket-art-aggression-replacement-training-2-utg/
VL  - 1
ER  -
TY  - JOUR
AB  - **Slutsatser**

- Insatser till familjehems&shy;placerade barn och familjehems&shy;f&ouml;r&auml;ldrar kan f&ouml;rb&auml;ttra barnens psykiska och fysiska h&auml;lsa, sociala situation, livskvalitet samt placeringars stabilitet. På grund av olikheter mellan insatserna och studiernas vetenskapliga utformning går det inte att avg&ouml;ra vilka insatser eller vilka delar av insatserna som &auml;r verksamma.

- F&ouml;r f&ouml;ljande tre specifika insatser finns något s&auml;krare kunskap om effekter:
  &ndash; Attachment and Biobehavioral Catch-up &auml;r en utbildning f&ouml;r familjehems&shy;f&ouml;r&auml;ldrar som kan minska vissa psykiska symtom hos barnen
  &ndash; F&ouml;r&auml;ldradelen av programmet Incredible Years kan minska barns beteende&shy;problem och &ouml;ka familjehems&shy;f&ouml;r&auml;ldrars f&ouml;rmåga att klara f&ouml;r&auml;ldrarollen
  &ndash; Take Charge &auml;r en special&shy;pedagogisk insats till ungdomar som kan f&ouml;rb&auml;ttra deras sj&auml;lv&shy;best&auml;mmande, utbildningsgång och m&ouml;jligheter till arbete.
F&ouml;r &ouml;vriga 15 insatser i denna utv&auml;rdering r&auml;cker inte underlaget f&ouml;r att bed&ouml;ma effekten. Att det saknas sådan kunskap om insatserna beh&ouml;ver inte betyda att de &auml;r verkningsl&ouml;sa.

Ingen av de insatser som anv&auml;nds i Sverige har utv&auml;rderats i en studie. I Sverige l&auml;ggs tonvikten på att utreda familjers l&auml;mplighet och att utbilda dem. Att erbjuda st&ouml;dinsatser till barn eller familjehems&shy;f&ouml;r&auml;ldrar under barnens placering &auml;r mindre vanligt. Personer som har v&auml;xt upp i familjehem, deras f&ouml;r&auml;ldrar och familjehems&shy;f&ouml;r&auml;ldrar efterlyser st&ouml;d till barn och familjehem under placeringen.

Det beh&ouml;vs forskning som unders&ouml;ker effekten av insatser inom familjehemsvård. Samtliga insatser som identifierades i litteratur&shy;&ouml;versikten b&ouml;r rimligtvis kunna anv&auml;ndas i Sverige men deras effekter beh&ouml;ver f&ouml;ljas upp och utv&auml;rderas i en svensk kontext. De insatser som redan f&ouml;rekommer i Sverige beh&ouml;ver också utv&auml;rderas och unders&ouml;kas vetenskapligt. Det beh&ouml;vs &auml;ven studier som belyser kostnads&shy;effektivitet i insatser f&ouml;r svenska f&ouml;rhållanden.

**Bakgrund och syfte**
Mellan 3 och 4 procent av alla barn i Sverige placeras någon gång i ett familjehem eller på en institution. Under sitt liv har dessa barn en f&ouml;rh&ouml;jd risk f&ouml;rsuicid, psykisk och fysisk oh&auml;lsa, missbruk, kriminalitet och behov av långvarigtf&ouml;rs&ouml;rjningsst&ouml;d. Syftet med denna rapport &auml;r att granska och sammanst&auml;lla detvetenskapliga underlaget f&ouml;r st&ouml;dinsatser till barn i familjehem och till familjehemsf&ouml;r&auml;ldrar f&ouml;r att minska dessa risker.

**Metod**
Den systematiska utv&auml;rderingen genomf&ouml;rdes i enlighet med SBU:s metodik.Studierna skulle behandla insatser som utv&auml;rderats i kontrollerade studier medh&ouml;g eller medelh&ouml;g studiekvalitet. Studierna skulle vara publicerade mellanåren 1990 och 2017 och inkludera minst 40 personer. Uppf&ouml;ljningstiden skullevara minst tre månader f&ouml;r barn två år eller &auml;ldre, och minst en månad f&ouml;r barnyngre &auml;n två år. Studier utesl&ouml;ts om j&auml;mf&ouml;relsegruppen utgjordes av gruppboende eller om den till stor del bestod av barn som var placerade i sl&auml;ktinghem. Den systematiska utv&auml;rderingen inkluderar &auml;ven ekonomiska aspekter,en inventering av vilka insatser som anv&auml;nds i Sverige, erfarenheter från brukarorganisationer samt en etisk analys.

**Resultat**
Effekter av insatserSammanlagt granskades 5 298 artikelsammanfattningar. Relevans- och kvalitetsgranskningen identifierade 23 studier av 18 insatser som motsvarade vårakriterier. Sammantaget visar de 23 studierna att det går att påverka familjehemsplacerade barns psykiska och fysiska h&auml;lsa, sociala situation, livskvalitetsamt placeringars stabilitet. På grund av olikheter mellan insatserna och studiernas vetenskapliga utformning ger resultaten inte entydiga svar på vilka insatsereller vilka delar av insatserna som &auml;r verksamma.

F&ouml;r tre av insatserna finns ett begr&auml;nsat vetenskapligt st&ouml;d f&ouml;r att de har effekt:Attachment and Biobehavioral Catch-up kan f&ouml;rb&auml;ttra barns psykiska h&auml;lsa(t.ex. minskad stress); Take Charge kan f&ouml;rb&auml;ttra barns f&ouml;rmåga till sj&auml;lvbest&auml;mmande samt sociala situation (t.ex. fullf&ouml;ljd utbildning) och Incredible Yearskan &ouml;ka familjehemsf&ouml;r&auml;ldrars f&ouml;rmåga att klara f&ouml;r&auml;ldrarollen och minskabarnens beteendeproblem. Effekterna av de &ouml;vriga 15 insatserna går inte attbed&ouml;ma eftersom de endast utv&auml;rderats i en studie vardera.

Det saknas helt studier som belyser barns tandh&auml;lsa och f&ouml;rebyggande av tonårsgraviditeter. Det saknas också studier av eventuella skadliga eller o&ouml;nskadeeffekter av insatserna.

**Praxisunders&ouml;kning**
En enk&auml;t skickades ut till ett slumpvis urval kommuner (svar från 80 av 106)och samtliga enskilda f&ouml;retag som arbetar på kommuners uppdrag (svar från 34av 38). Enk&auml;ten identifierade 30 insatser. Ingen av insatserna återfinns i litteratur&ouml;versikten. Det framkom bland annat att insatserna fokuserar på bed&ouml;mningav l&auml;mplighet av familjehemsf&ouml;r&auml;ldrar och på allm&auml;n utbildning av dem f&ouml;rebarnen placeras. Det var mindre vanligt med st&ouml;d till barn eller familjehemsf&ouml;r&auml;ldrar under placeringen. Att d&ouml;ma av de insatser som anv&auml;nds saknas konsensus om vilka insatser som uppfattas som effektiva.

**Kostnadseffektivitet**
Totalt granskades 2 120 artikelsammanfattningar. Två relevanta artiklar hittadesmen ingen uppfyllde SBU:s krav på kvalitet i den ekonomiska utv&auml;rderingen.Studiernas resultat går inte att &ouml;verf&ouml;ra till svenska f&ouml;rhållanden.

**Brukar- och anh&ouml;rigperspektiv**
Fyra organisationer som f&ouml;retr&auml;der barn med erfarenhet av familjehemsvård,deras f&ouml;r&auml;ldrar samt familjehemsf&ouml;r&auml;ldrar besvarade enk&auml;ter eller intervjuades.De efterlyser mer st&ouml;d ut&ouml;ver sj&auml;lva placeringen. Dessutom &ouml;nskar familjehemsf&ouml;r&auml;ldrar b&auml;ttre kunskap om barnets behov vid placeringen och ursprungsf&ouml;r&auml;ldrarna efterlyser st&ouml;d f&ouml;r att få vara delaktiga i sina barns liv.

**Etiska och sociala aspekter**
N&auml;r samh&auml;llet &ouml;vertar ansvaret f&ouml;r barns vårdnad så finns en s&auml;rskild skyldighetatt tillgodose barnens b&auml;sta. Att samh&auml;llet inte alltid tagit sitt ansvar visar blandannat den så kallade Vanvårdsutredningen (SOU 2011:61). Ett problem &auml;rbristen på vetenskaplig kunskap om insatsers f&ouml;r- och nackdelar vilket &auml;ventyrarbarns r&auml;ttigheter. Ett annat problem &auml;r bristande dokumentation och uppf&ouml;ljning av de insatser som anv&auml;nds.

**Diskussion**
Vi bed&ouml;mer att insatserna från litteratur&ouml;versikten kan anv&auml;ndas i svenskfamiljehemsvård med &ouml;verf&ouml;rbara resultat f&ouml;r barnen. Om beslut fattas attinf&ouml;ra nya insatser b&ouml;r man vara uppm&auml;rksam på att många kommuner &auml;r småmed få placerade barn, vilket kan skapa problem med att uppr&auml;tthålla tillr&auml;ckligkompetens. De som arbetar i familjehemsvården &auml;r många gånger ovana vidden systematik som insatserna kr&auml;ver. &Auml;ven med &ouml;kad tillgång på vetenskapligkunskap om insatsers effekter beh&ouml;vs rutiner f&ouml;r att på ett ordnat s&auml;tt inf&ouml;ra,vidmakthålla och utm&ouml;nstra insatser inom familjehemsvården. Detta kan skegenom lokal uppf&ouml;ljning d&auml;r både positiva och negativa effekter f&ouml;ljs upp systematiskt och dokumenteras. I f&ouml;rl&auml;ngningen ger det m&ouml;jlighet till uppbyggnadav kvalitetsregister.Framtida forskning b&ouml;r inriktas på att unders&ouml;ka nyttan av de insatser somanv&auml;nds idag eller som kan komma att inf&ouml;ras.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /sv/publikationer/SBU-utvarderar/insatser-for-battre-psykisk-och-fysisk-halsa-hos-familjehemsplacerade-barn/
L1  - internal-pdf://4014390231/insatser_battre_psykisk_fysisk_halsa_familjehe.pdf
PY  - 2017
TI  - Insatser f&ouml;r b&auml;ttre psykisk och fysisk h&auml;lsa hos familjehemsplacerade barn
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
An increasing number of abandoned clinical trials have forestalled efforts to advance the evidence base for the treatment of mood and anxiety disorders in children and adolescents. With this in mind, we sought to present and validate a Bayesian approach for the reanalysis of summary data in abandoned clinical trials and to review and re-evaluate available pharmacokinetic, tolerability, and efficacy data from two large, randomized controlled trials of buspirone in pediatric patients with generalized anxiety disorder (GAD). 

**METHODS: **
Prospective, randomized, parallel-group controlled trials of buspirone in pediatric patients with GAD as well as associated pharmacokinetic studies were identified and data were extracted. In addition to descriptive statistics, marginal posterior densities for each variable of interest were determined and a Monte Carlo pseudosample was generated with random draws obtained from the Student&#039;s t-distribution to assess, with inferential statistics, differences in variables of interest. 

**RESULTS: **
Buspirone was evaluated in one flexibly dosed (N=227) and one fixed-dose (N=341) trial in children and adolescents aged 6-17 years with a primary diagnosis of GAD. With regard to improvement in the sum of the Columbia Schedule for Affective Disorders and Schizophrenia GAD items, buspirone did not separate from placebo in the fixed-dose trial at low (95% CI: -0.78 to 2.39, p=0.32) or high dose (95% CI: -0.87 to 1.87, p=0.47) nor did it separate from placebo in the flexibly dosed study (95% CI: -0.3 to 1.9, p=0.15). Drop out as a result of a treatment-emergent adverse event was significantly greater in buspirone-treated patients compared to placebo (p=0.011). Side effects were consistent with the known profile of buspirone with lightheadedness occurring more frequently in buspirone-treated patients (p&lt;0.001). 

**CONCLUSIONS:**
Buspirone is well tolerated in pediatric patients with GAD, although two randomized controlled trials were underpowered to detect small effect sizes (Cohen&#039;s d&lt;0.15). Finally, Bayesian approaches may facilitate re-examination of data from abandoned clinical trials.
AN  - 28846022
AU  - Strawn,
AU  - J.
AU  - R.
AU  - Mills,
AU  - J.
AU  - A.
AU  - Cornwall,
AU  - G.
AU  - J.
AU  - Mossman,
AU  - S.
AU  - A.
AU  - Varney,
AU  - S.
AU  - T.
AU  - Keeshin,
AU  - B.
AU  - R.
AU  - Croarkin,
AU  - P.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/cap.2017.0060
L1  - internal-pdf://2086392417/Strawn-2017-Buspirone in Children and Adolesce.pdf
PY  - 2017
SP  - 28
TI  - Buspirone in Children and Adolescents with Anxiety: A Review and Bayesian Analysis of Abandoned Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28846022
VL  - 28
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To assess the efficacy and safety of neurostimulation compared with control groups in the treatment of pediatric primary enuresis by performing meta-analysis of randomized controlled trials (RCTs). 

**METHODS: **
A systematic literature search with no language restriction was performed in August 2016. RCTs were identified and evaluated according to the Cochrane Collaboration risk of bias assessment recommendations. The number of patients with post-treatment responses such as partial response (PR) (50%-89%), complete response (CR) (&gt;=90%), and full response (FR) (100%) were extracted for relative risk (RR) and 95% confidence interval (CI). Effect estimates were pooled using the Mantel-Haenszel method. The review protocol was registered in the PROSPERO registry (CRD42016043502). 

**RESULTS: **
A total of 292 subjects from 7 nonheterogeneous RCTs were included for meta-analysis. Pooled effect estimate of subjects with &gt;=50% post-treatment wet-night reduction (PR, CR, and FR) showed a significantly better outcome after neurostimulation compared with controls (RR = 2.20, 95% CI 1.66, 2.90), whereas patients with &gt;=90% post-treatment wet-night reduction (CR and FR) showed a significantly better outcome in the neurostimulation groups (RR = 2.79, 95% CI 1.54, 5.06). Furthermore, a significant mean difference in wet-night reduction per week was noted between treatment groups in favor of neurostimulation treatment (mean difference -1.95, 95% CI -2.84, -1.07). No serious adverse effects were noted related to neurostimulation therapy. 

**CONCLUSION: **
Current evidence suggests that neurostimulation therapy is efficacious and safe for the treatment of PPE. Head-to-head randomized clinical trials are needed to further assess relative efficacy among variable treatment protocols.
AN  - 28476683
AU  - Chua,
AU  - M.
AU  - E.
AU  - Fernandez,
AU  - N.
AU  - Ming,
AU  - J.
AU  - M.
AU  - Silangcruz,
AU  - J.
AU  - M.
AU  - A.
AU  - Dos
AU  - Santos,
AU  - J.
AU  - Lorenzo,
AU  - A.
AU  - J.
AU  - Koyle,
AU  - M.
AU  - A.
AU  - Lopes,
AU  - R.
AU  - I.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.urology.2017.04.035
L1  - internal-pdf://3962769995/Chua-2017-Neurostimulation Therapy for Pediatr.pdf
PY  - 2017
SP  - 183-187
T2  - Urology
TI  - Neurostimulation Therapy for Pediatric Primary Enuresis: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=28476683
UR  - https://ac.els-cdn.com/S0090429517304089/1-s2.0-S0090429517304089-main.pdf?_tid=10572129-989f-45ff-92dd-b9901c9a6cf0&amp;acdnat=1547554155_041b7486dd1a1677f2ecddcde0f31135
VL  - 106
ER  -
TY  - JOUR
AB  - **Background: **
The risk-benefit balance of pharmacological treatment for children and adolescents with ADHD and the factors that moderate this relationship are unclear. 

**Methods: **
A systematic review and meta-analysis of randomised, placebo-controlled clinical trials (RPCCTs) investigating the efficacy of pharmacological treatment in children or adolescents with ADHD was carried out. Meta-analysis of treatment discontinuation, clinician-, parent- and teacher-rated efficacy and adverse events was performed. The effect of covariates was studied. 

**Results: **
Sixty-three studies were included. Ten drugs were investigated, with atomoxetine and methylphenidate the most frequently studied. RPCCTs had mostly a short duration (7.9 weeks). All-cause treatment discontinuation was lower with pharmacological treatment than placebo (OR = 0.68). Pharmacological treatment was more efficacious than placebo independently of the rater (clinician, standardised mean difference (SMD) 0.74; parent, SMD = 0.63; or teacher, SMD = 0.75). Evidence of publication bias was found for clinician-rated efficacy, especially in industry-sponsored RPCCT. Psychostimulants showed a higher efficacy and were associated with a better outcome on treatment discontinuation than non-stimulant drugs. Efficacy was smaller in RPCCTs for which a psychiatric comorbid disorder was an inclusion criterion, was larger in studies with a commercial sponsorship and showed a negative association with treatment length. 

**Conclusions: **
In the short term, pharmacological treatment provides moderate-high symptom relief, is safe and shows lower treatment discontinuation than placebo, suggesting a suitable risk-benefit balance, particularly with psychostimulants. The efficacy is lower in patients with a comorbid psychiatric disorder and should be assessed periodically, as it appears to reduce over time. Publication bias of clinician-rated efficacy in studies with a commercial sponsor is suggested. 

Copyright &copy; 2017, Springer-Verlag Berlin Heidelberg.
AN  - 616899979
AU  - Riera,
AU  - M.
AU  - Castells,
AU  - X.
AU  - Tobias,
AU  - A.
AU  - Cunill,
AU  - R.
AU  - Blanco,
AU  - L.
AU  - Capella,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00213-017-4662-1
L1  - internal-pdf://3985102704/Riera-2017-Discontinuation of pharmacological.pdf
PY  - 2017
SP  - 2657-2671
TI  - Discontinuation of pharmacological treatment of children and adolescents with attention deficit hyperactivity disorder: meta-analysis of 63 studies enrolling 11,788 patients
UR  - http://link.springer.de/link/service/journals/00213/index.htm
VL  - 234
ER  -
TY  - JOUR
AB  - Cognitive remediation therapy (CRT) for eating disorders has demonstrated promising findings in adult age groups, with randomised treatment trials and systematic reviews demonstrating medium to large effect sizes in improved cognitive performance. 

In recent years, several case series have been conducted for young people with anorexia nervosa, but these findings have not been synthesised in the form of a systematic review. 

This systematic review aimed to evaluate the evidence for the efficacy of CRT in child and adolescent age groups. 

Nine studies were identified, with a subsequent meta-analysis suggesting improvements in cognitive performance with small effect sizes. 

Patient feedback was positive, with low dropout rates. 

These findings suggest that CRT has potential as a supplementary treatment for young people with anorexia nervosa, warranting further investigation using randomised treatment trials. 

Copyright &copy; 2017 John Wiley &amp; Sons, Ltd and Eating Disorders Association.
AN  - 616605541
AU  - Tchanturia,
AU  - K.
AU  - Giombini,
AU  - L.
AU  - Leppanen,
AU  - J.
AU  - Kinnaird,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/erv.2522
L1  - internal-pdf://2984541519/Tchanturia-2017-Evidence for Cognitive Remedia.pdf
PY  - 2017
SP  - 227-236
TI  - Evidence for Cognitive Remediation Therapy in Young People with Anorexia Nervosa: Systematic Review and Meta-analysis of the Literature
UR  - http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1099-0968
VL  - 25
ER  -
TY  - JOUR
AB  - Background
Maternal complications including psychological and mental health problems and neonatal morbidity have been commonly observed in the postpartum period. Home visits by health professionals or lay supporters in the weeks following the birth may prevent health problems from becoming chronic with long‐term effects on women, their babies, and their families.

Objectives
To assess outcomes for women and babies of different home‐visiting schedules during the early postpartum period. The review focuses on the frequency of home visits, the duration (when visits ended) and intensity, and on different types of home‐visiting interventions.

Search methods
We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (28 January 2013) and reference lists of retrieved articles.

Selection criteria
Randomised controlled trials (RCTs) (including cluster‐RCTs) comparing different types of home‐visiting interventions enrolling participants in the early postpartum period (up to 42 days after birth). We excluded studies in which women were enrolled and received an intervention during the antenatal period (even if the intervention continued into the postnatal period) and studies recruiting only women from specific high‐risk groups. (e.g. women with alcohol or drug problems).

Data collection and analysis
Study eligibility was assessed by at least two review authors. Data extraction and assessment of risk of bias were carried out independently by at least two review authors. Data were entered into Review Manager software.

Main results
We included data from 12 randomised trials with data for more than 11,000 women. The trials were carried out in countries across the world, and in both high‐ and low‐resource settings. In low‐resource settings women receiving usual care may have received no additional postnatal care after early hospital discharge.

The interventions and control conditions varied considerably across studies with trials focusing on three broad types of comparisons: schedules involving more versus fewer postnatal home visits (five studies), schedules involving different models of care (three studies), and home versus hospital clinic postnatal check‐ups (four studies). In all but two of the included studies, postnatal care at home was delivered by healthcare professionals. The aim of all interventions was broadly to assess the wellbeing of mothers and babies, and to provide education and support, although some interventions had more specific aims such as to encourage breastfeeding, or to provide practical support.

For most of our outcomes only one or two studies provided data, and overall results were inconsistent.

There was no evidence that home visits were associated with improvements in maternal and neonatal mortality, and no consistent evidence that more postnatal visits at home were associated with improvements in maternal health. More intensive schedules of home visits did not appear to improve maternal psychological health and results from two studies suggested that women receiving more visits had higher mean depression scores. The reason for this finding was not clear. In a cluster randomised trial comparing usual care with individualised care by midwives extended up to three months after the birth, the proportions of women with Edinburgh postnatal depression scale (EPDS) scores &ge; 13 at four months was reduced in the individualised care group (RR 0.68, 95% CI 0.53 to 0.86). There was some evidence that postnatal care at home may reduce infant health service utilisation in the weeks following the birth, and that more home visits may encourage more women to exclusively breastfeed their babies. There was some evidence that home visits are associated with increased maternal satisfaction with postnatal care.

Authors&#039; conclusions
Increasing the number of postnatal home visits may promote infant health and maternal satisfaction and more individualised care may improve outcomes for women, although overall findings in different studies were not consistent. The frequency, timing, duration and intensity of such postnatal care visits should be based upon local and individual needs. Further well designed RCTs evaluating this complex intervention will be required to formulate the optimal package.
AN  - CD009326
AU  - Yonemoto,
AU  - N.
AU  - Dowswell,
AU  - T.
AU  - Nagai,
AU  - S.
AU  - Mori,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009326.pub2
KW  - House Calls [statistics &amp; numerical data]
KW  - Infant Mortality
KW  - Maternal Mortality
KW  - Perinatal Mortality
KW  - Postnatal Care [organization &amp; administration] [statistics &amp; numerical data]
KW  - Postpartum Period
KW  - Randomized Controlled Trials as Topic
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Infant, Newborn[checkword]
KW  - Preg
L1  - internal-pdf://2682949186/Yonemoto-2013-Schedules for home visits in the.pdf
PY  - 2017
T2  - Cochrane Database of Systematic Reviews
TI  - Schedules for home visits in the early postpartum period
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009326.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009326.pub2/asset/CD009326.pdf?v=1&amp;t=iw7l2fke&amp;s=7edc25f5c9cc0694743fdf734abf9dd3607524c0
UR  - http://onlinelibrary.wiley.com/store/10.1002/14651858.CD009326.pub3/asset/CD009326.pdf?v=1&amp;t=j8ygqchn&amp;s=ef15ab2278fa336fa02a992dcccc7b2ae44e6d93
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Adolescent depression is common and leads to distress and impairment for individuals/families. Treatment/prevention guidelines stress the need for good information and evidence-based psychosocial interventions. There has been growing interest in psychoeducational interventions (PIs), which broadly deliver accurate information about health issues and self-management. 

**OBJECTIVE, METHODS: **
Systematic search of targeted PIs as part of prevention/management approaches for adolescent depression. Searches were undertaken independently in PubMed, PsycINFO, EMBASE, guidelines, reviews (including Cochrane), and reference lists. Key authors were contacted. No restrictions regarding publishing dates. 

**RESULTS: **
Fifteen studies were included: seven targeted adolescents with depression/depressive symptoms, eight targeted adolescents &#039;at risk&#039; e.g. with a family history of depression. Most involved family/group programmes; others included individual, school-based and online approaches. PIs may affect understanding of depression, identification of symptoms, communication, engagement, and mental health outcomes. 

**CONCLUSION, PRACTICE IMPLICATIONS: **
PIs can have a role in preventing/managing adolescent depression, as a first-line or adjunctive approach. The limited number of studies, heterogeneity in formats and evaluation, and inconsistent approach to defining PI, make it difficult to compare programmes and measure overall effectiveness. Further work needs to establish an agreed definition of PI, develop/evaluate PIs in line with frameworks for complex interventions, and analyse their active components.
AN  - 29103882
AU  - Bevan
AU  - Jones,
AU  - R.
AU  - Thapar,
AU  - A.
AU  - Stone,
AU  - Z.
AU  - Thapar,
AU  - A.
AU  - Jones,
AU  - I.
AU  - Smith,
AU  - D.
AU  - Simpson,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.pec.2017.10.015
L1  - internal-pdf://0601980614/Bevan Jones-2017-Psychoeducational interventio.pdf
PY  - 2017
SP  - 24
T2  - Patient Education &amp; Counseling
TI  - Psychoeducational interventions in adolescent depression: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29103882
VL  - 24
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Some studies have indicated the efficacy of quetiapine in the treatment of bipolar depression in adult patients. However, its efficacy has been not shown in child and adolescent patients. 

**OBJECTIVE: **
This systematic review purposefully determined the efficacy and acceptability of quetiapine in the treatment of children and adolescents with bipolar depression. 

**DATA SOURCES:**
A database search of EMBASE, PubMed, CINAHL, and Cochrane Controlled Trials Register was carried out in March 2016. All randomized controlled trials (RCTs) of bipolar depression in children and adolescents were considered for inclusion in this review.

**STUDY ELIGIBILITY CRITERIA PARTICIPANTS AND INTERVENTIONS: **
RCTs of quetiapine in the treatment of child and adolescent patients with bipolar depression with end point outcomes were included in this study. Languages were not limited. 

**STUDY APPRAISAL AND SYNTHESIS METHODS: **
The full-text versions of relevant clinical studies were thoroughly examined and extracted. The primary efficacy of outcome was measured by using the pooled mean-changed scores of the rating scales for bipolar depression. However, the response and remission rates were also measured. 

**RESULTS: **
A total of 251 randomized patients in the three RCTs of quetiapine versus placebo in the treatment of bipolar depression for children and adolescents were eligible in this review. The pooled mean-changed score of the quetiapine-treated group was not greater than that of the placebo-treated group. Similarly, the pooled response and remission rates were not different between the two groups. The pooled overall discontinuation rate and the discontinuation rate due to adverse events were not different between the two groups. 

**LIMITATIONS: **
Limited studies were eligible in this review. 

**CONCLUSION: **
According to the findings in this review, quetiapine may not be efficacious in the treatment of bipolar depression in children and adolescents. Its acceptability, however, was comparable to a placebo. Therefore, the use of quetiapine in children and adolescents with bipolar depression is not recommended. Further well-defined clinical studies should be performed to confirm these outcomes.
AN  - 28435272
AU  - Maneeton,
AU  - B.
AU  - Putthisri,
AU  - S.
AU  - Maneeton,
AU  - N.
AU  - Woottiluk,
AU  - P.
AU  - Suttajit,
AU  - S.
AU  - Charnsil,
AU  - C.
AU  - Srisurapanont,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2147/NDT.S121517
L1  - internal-pdf://2130078908/Maneeton-2017-Quetiapine monotherapy versus pl.pdf
PY  - 2017
TI  - Quetiapine monotherapy versus placebo in the treatment of children and adolescents with bipolar depression: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28435272
VL  - 13
ER  -
TY  - GEN
AB  - **Background:** 
Iodine is an essential nutrient required for the biosynthesis of thyroid hormones, which are responsible for regulating growth, development and metabolism. Iodine requirements increase substantially during pregnancy and breastfeeding. If requirements are not met during these periods, the production of thyroid hormones may decrease and be inadequate for maternal, fetal and infant needs. The provision of iodine supplements may help meet the increased iodine needs during pregnancy and the postpartum period and prevent or correct iodine deficiency and its consequences.

**Objectives:** 
To assess the benefits and harms of supplementation with iodine, alone or in combination with other vitamins and minerals, for women in the preconceptional, pregnancy or postpartum period on their and their children&#039;s outcomes.

**Search methods:** 
We searched Cochrane Pregnancy and Childbirth&#039;s Trials Register (14 November 2016), and the WHO International Clinical Trials Registry Platform (ICTRP) (17 November 2016), contacted experts in the field and searched the reference lists of retrieved studies and other relevant papers.

**Selection criteria:** 
Randomized and quasi-randomized controlled trials with randomisation at either the individual or cluster level comparing injected or oral iodine supplementation (such as tablets, capsules, drops) during preconception, pregnancy or the postpartum period irrespective of iodine compound, dose, frequency or duration.

**Data collection and analysis:** 
Two review authors independently assessed trial eligibility, risk of bias, extracted data and conducted checks for accuracy. We used the GRADE approach to assess the quality of the evidence for primary outcomes.We anticipated high heterogeneity among trials, and we pooled trial results using random-effects models and were cautious in our interpretation of the pooled results.

**Main results:** 
We included 14 studies and excluded 48 studies. We identified five ongoing or unpublished studies and two studies are awaiting classification. Eleven trials involving over 2700 women contributed data for the comparisons in this review (in three trials, the primary or secondary outcomes were not reported). Maternal primary outcomesIodine supplementation decreased the likelihood of the adverse effect of postpartum hyperthyroidism by 68% (average risk ratio (RR) 0.32; 95% confidence interval (CI) 0.11 to 0.91, three trials in mild to moderate iodine deficiency settings, 543 women, no statistical heterogeneity, low-quality evidence) and increased the likelihood of the adverse effect of digestive intolerance in pregnancy by 15 times (average RR 15.33; 95% CI 2.07 to 113.70, one trial in a mild-deficiency setting, 76 women, very low-quality evidence).There were no clear differences between groups for hypothyroidism in pregnancy or postpartum (pregnancy: average RR 1.90; 95% CI 0.57 to 6.38, one trial, 365 women, low-quality evidence, and postpartum: average RR 0.44; 95% CI 0.06 to 3.42, three trials, 540 women, no statistical heterogeneity, low-quality evidence), preterm birth (average RR 0.71; 95% CI 0.30 to 1.66, two trials, 376 women, statistical heterogeneity, low-quality evidence) or the maternal adverse effects of elevated thyroid peroxidase antibodies (TPO-ab) in pregnancy or postpartum (average RR 0.95; 95% CI 0.44 to 2.07, one trial, 359 women, low-quality evidence, average RR 1.01; 95% CI 0.78 to 1.30, three trials, 397 women, no statistical heterogeneity, low-quality evidence), or hyperthyroidism in pregnancy (average RR 1.90; 95% CI 0.57 to 6.38, one trial, 365 women, low-quality evidence). All of the trials contributing data to these outcomes took place in settings with mild to moderate iodine deficiency. Infant/child primary outcomesCompared with those who did not receive iodine, those who received iodine supplements had a 34% lower likelihood of perinatal mortality, however this difference was not statistically significant (average RR 0.66; 95% CI 0.42 to 1.03, two trials, 457 assessments, low-quality evidence). All of the perinatal deaths occurred in one trial conduct d in a severely iodine-deficient setting. There were no clear differences between groups for low birthweight (average RR 0.56; 95% CI 0.26 to 1.23, two trials, 377 infants, no statistical heterogeneity, low-quality evidence), neonatal hypothyroidism/elevated thyroid-stimulating hormone (TSH) (average RR 0.58; 95% CI 0.11 to 3.12, two trials, 260 infants, very low-quality evidence) or the adverse effect of elevated neonatal thyroid peroxidase antibodies (TPO-ab) (average RR 0.61; 95% CI 0.07 to 5.70, one trial, 108 infants, very low-quality evidence). All of the trials contributing data to these outcomes took place in areas with mild to moderate iodine deficiency. No trials reported on hypothyroidism/elevated TSH or any adverse effect beyond the neonatal period.

**Authors&#039; conclusions:** 
There were insufficient data to reach any meaningful conclusions on the benefits and harms of routine iodine supplementation in women before, during or after pregnancy. The available evidence suggested that iodine supplementation decreases the likelihood of postpartum hyperthyroidism and increases the likelihood of the adverse effect of digestive intolerance in pregnancy - both considered potential adverse effects. We considered evidence for these outcomes low or very low quality, however, because of study design limitations and wide confidence intervals. In addition, due to the small number of trials and included women in our meta-analyses, these findings must be interpreted with caution. There were no clear effects on other important maternal or child outcomes though these findings must also be interpreted cautiously due to limited data and low-quality trials. Additionally, almost all of the evidence came from settings with mild or moderate iodine deficiency and therefore may not be applicable to settings with severe deficiency. More high-quality randomised controlled trials are needed on iodine supplementation before, during and after pregnancy on maternal and infant/child outcomes. However, it may be unethical to compare iodine to placebo or no treatment in severe deficiency settings. Trials may also be unfeasible in settings where pregnant and lactating women commonly take prenatal supplements with iodine. Information is needed on optimal timing of initiation as well as supplementation regimen and dose. Future trials should consider the outcomes in this review and follow children beyond the neonatal period. Future trials should employ adequate sample sizes, assess potential adverse effects (including the nature and extent of digestive intolerance), and be reported in a way that allows assessment of risk of bias, full data extraction and analysis by the subgroups specified in this review.
AN  - CD011761
AU  - Harding,
AU  - K.
AU  - B.
AU  - Pe&ntilde;a-Rosas
AU  - Juan,
AU  - P.
AU  - Webster,
AU  - A.
AU  - C.
AU  - Yap,
AU  - C.
AU  - Payne,
AU  - B.
AU  - A.
AU  - Ota,
AU  - E.
AU  - De-Regil
AU  - Luz,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd011761.pub2
L1  - internal-pdf://1101526380/Harding Kimberl-2017-Iodine supplementation fo.pdf
PY  - 2017
T2  - Cochrane Database of Systematic Reviews
TI  - Iodine supplementation for women during the preconception, pregnancy and postpartum period
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD011761.pub2/abstract
UR  - http://onlinelibrary.wiley.com/store/10.1002/14651858.CD011761.pub2/asset/CD011761.pdf?v=1&amp;t=j82wot78&amp;s=eb65b87cb7aa805e9095825873c4a18b9955b694
ER  -
TY  - JOUR
AB  - Interventions to improve nutritional status of young children in low- and middle-income countries (LMIC) may have the added benefit of improving their mental and motor development. 

This meta-analysis updates and goes beyond previous ones by answering two important questions: (1) do prenatal and postnatal nutritional inputs improve mental development, and (2) are effects on mental development associated with two theoretically interesting mediators namely physical growth and motor development? 

The meta-analysis of articles on Medline, PsycINFO, Global Health and Embase was limited to randomized trials in LMICs, with mental development of children from birth to age two years as an outcome. The initial yield of 2689 studies was reduced to 33; 12 received a global quality rating of strong. 

Of the 10 prenatal and 23 postnatal nutrition interventions, the majority used zinc, iron/folic acid, vitamin A or multiple micronutrients, with a few evaluating macronutrients. The weighted mean effect size, Cohen&#039;s d (95% CI) for prenatal and postnatal nutrition interventions on mental development was 0.042 (-0.0084, 0.092) and 0.076 (0.019, 0.13), respectively. 

Postnatal supplements consisting of macronutrients yielded an effect size d (95% CI) of 0.14 (0.0067, 0.27), multiple micronutrients 0.082 (-0.012, 0.18) and single micronutrients 0.058 (-0.0015, 0.12). Motor development, but not growth status, effect sizes were significantly associated with mental development in postnatal interventions. In summary, nutrition interventions had small effects on mental development. 

Future studies might have greater effect if they addressed macronutrient deficiencies combined with child stimulation and hygiene and sanitation interventions. 

Copyright &copy; 2015 John Wiley &amp; Sons Ltd.
AD  - Larson, Leila Margaret. Emory University, Nutrition and Health Sciences Program, Laney Graduate School, Atlanta, Georgia, USA. Yousafzai, Aisha K. Aga Khan University, Department of Paediatrics and Child Health, Division of Women and Child Health, Karachi, Sindh, Pakistan.
AN  - 26607403
AU  - Larson,
AU  - L.
AU  - M.
AU  - Yousafzai,
AU  - A.
AU  - K.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/mcn.12229
DP  - Ovid Technologies
J2  - Matern Child Nutr
L1  - internal-pdf://1249850002/Larson-2017-A meta-analysis of nutrition inter.pdf
LA  - English
M3  - Review
N1  - Larson, Leila Margaret Yousafzai, Aisha K Using Smart Source Parsing Jan
PY  - 2017
T2  - Maternal &amp; Child Nutrition
TI  - A meta-analysis of nutrition interventions on mental development of children under-two in low- and middle-income countries
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26607403http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26607403&amp;id=doi:10.1111%2Fmcn.12229&amp;issn=1740-8695&amp;isbn=&amp;volume=13&amp;issue=1&amp;spage=e12229&amp;pages=&amp;date=2017&amp;title=Maternal+%26+Child+Nutrition&amp;atitle=A+meta-analysis+of+nutrition+interventions+on+mental+development+of+children+under-two+in+low-+and+middle-income+countries.&amp;aulast=Larson&amp;pid=%3Cauthor%3ELarson+LM%3C%2Fauthor%3E%3CAN%3E26607403%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1111/mcn.12229/asset/mcn12229.pdf?v=1&amp;t=j02f2r8d&amp;s=b98aeb1116089fe88ff0ea73e20c291a3b871360
VL  - 13
ER  -
TY  - JOUR
AB  - The current study undertook a narrative and meta-analytic review of the literature to examine the effectiveness of group-based in-service foster parent training programs in reducing externalizing child behaviors. 

All studies reported a significant decrease in at least one measure of child behavior problems for treatment-group participants. 

The programs appear to be effective across ethnically and nationally diverse samples and produce similar results for older and younger children, as well as boys and girls. 

Overall the evidence suggests that group-based foster parent programs are an effective method for reducing problem behaviors among children in out of home care. 

(PsycINFO Database Record (c) 2018 APA, all rights reserved)
AN  - 2017-58177-005
AU  - Uretsky,
AU  - M.
AU  - C.
AU  - Hoffman,
AU  - J.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15548732.2017.1326360
L1  - internal-pdf://1203435099/Uretsky-2017-Evidence for group-based foster p.pdf
PY  - 2017
SP  - 464-486
T2  - Journal of Public Child Welfare
TI  - Evidence for group-based foster parent training programs in reducing externalizing child behaviors: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2017-58177-005
UR  - https://www.tandfonline.com/doi/pdf/10.1080/15548732.2017.1326360?needAccess=true
VL  - 11
ER  -
TY  - JOUR
AB  - We aimed to establish the treatment effect of physical activity for depression in young people through meta-analysis. Four databases were searched to September 2016 for randomised controlled trials of physical activity interventions for adolescents and young adults, 12-25 years, experiencing a diagnosis or threshold symptoms of depression. 

Random-effects meta-analysis was used to estimate the standardised mean difference (SMD) between physical activity and control conditions. Subgroup analysis and meta-regression investigated potential treatment effect modifiers. Acceptability was estimated using dropout. Trials were assessed against risk of bias domains and overall quality of evidence was assessed using GRADE criteria. 

Seventeen trials were eligible and 16 provided data from 771 participants showing a large effect of physical activity on depression symptoms compared to controls (SMD = -0.82, 95% CI = -1.02 to -0.61, p &lt; 0.05, I 2 = 38%). The effect remained robust in trials with clinical samples (k = 5, SMD = -0.72, 95% CI = -1.15 to -0.30), and in trials using attention/activity placebo controls (k = 7, SMD = -0.82, 95% CI = -1.05 to -0.59). Dropout was 11% across physical activity arms and equivalent in controls (k = 12, RD = -0.01, 95% CI = -0.04 to 0.03, p = 0.70). 

However, the quality of RCT-level evidence contributing to the primary analysis was downgraded two levels to LOW (trial-level risk of bias, suspected publication bias), suggesting uncertainty in the size of effect and caution in its interpretation. While physical activity appears to be a promising and acceptable intervention for adolescents and young adults experiencing depression, robust clinical effectiveness trials that minimise risk of bias are required to increase confidence in the current finding. 

The specific intervention characteristics required to improve depression remain unclear, however best candidates given current evidence may include, but are not limited to, supervised, aerobic-based activity of moderate-to-vigorous intensity, engaged in multiple times per week over eight or more weeks. Further research is needed. (Registration: PROSPERO-CRD 42015024388).
AN  - 28994355
AU  - Bailey,
AU  - A.
AU  - P.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Rosenbaum,
AU  - S.
AU  - Purcell,
AU  - R.
AU  - Parker,
AU  - A.
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1017/S0033291717002653
L1  - internal-pdf://1168710404/Bailey-2017-Treating depression with physical.pdf
PY  - 2017
SP  - 1-20
TI  - Treating depression with physical activity in adolescents and young adults: a systematic review and meta-analysis of randomised controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28994355
ER  -
TY  - JOUR
AB  - **Background**
Sexual offender treatment programs to reduce reoffending have been implemented in many countries as part of a strategy in managing this offender group. However, there are still controversies regarding their effectiveness.

**Objectives**
A meta-analysis of relatively well-controlled outcome evaluations assessing the effects of treatment for male sexual offenders to reduce recidivism is conducted. The aim is to provide robust estimates of overall and differential treatment effects.

**Search methods**
We searched a broad range of literature databases, scanned previous reviews and primary studies on the topic, hand-searched 16 relevant journals, carried out an internet search of pertinent institutions, and personally contacted experts in the field of sex offender treatment. In total, we identified more than 3,000 documents that were scanned for eligibility.

**Selection criteria**
Studies had to address male sexual offenders and contain an outcome evaluation with a treated group (TG) and an equivalent control group (CG). Apart from randomized controlled trials (RCTs), also quasi-experimental designs were eligible if they applied sound matching procedures, statistically controlled for potential biases or the incidental assignment would not introduce bias. The studies had to evaluate therapeutic measures aiming at reducing recidivism. Both, psychosocial and organic treatment approaches were eligible. Case reports were not eligible and sample size had to be at least n =10. To be eligible, studies had to report official recidivism data as an outcome and provide sufficient information for effect size calculation. There were no restrictions with regard to country of origin or language and both published and unpublished documents were eligible.

**Data collection and analysis**
For each study/comparison we coded general features, characteristics of the sample, treatment variables and methodological features. As most studies reported their results in terms of recidivism rates, we chose the odds ratio (OR) as effect size measure. If results on treatment dropouts were provided, we merged them with the treatment group results (&ldquo;intent to treat&rdquo; analysis). All statistical analysis of effect sizes applied a random effects model.

**Results**
29 comparisons drawn from 27 studies met our inclusion criteria. This study pool comprised 4,939 treated and 5,448 untreated offenders. A quarter of the studies were retrieved from unpublished sources. Most studies appeared since 2000 and more than half came from North America. The evaluations mostly addressed cognitive-behavioral sex offender treatment. No study on hormonal treatment met the inclusion criteria. Only about one fifth of the comparisons were RCTs and matching designs were rare as well. The follow-up periods ranged from 1 to 19.5 years (M = 5.9 years). Most frequently recidivism was defined as a new conviction and with only one exception studies presented data on sexual reoffending.Overall, there was a positive, statistically significant effect of treatment on sexual reoffending (OR = 1.41, 95% CI: 1.11 to 1.78, p &lt; .01). The mean effect equates to 26.3% less recidivism after treatment (sexual recidivism rate of 10.1% in treated sex offenders vs. 13.7 % in the control groups). There was a comparable effect on general recidivism (26.4% less recidivism in treated groups; OR = 1.45, 95% CI: 1.15 to 1.83, p &lt; .01). The overall effects were robust against outliers, but contained much heterogeneity.Cognitive-behavioral programs showed a significant effect. Two RCTs on Multi-Systemic Therapy (MST) which also contains many cognitive-behavioral elements revealed a particularly large effect. Other intervention types showed weaker or no effects. There was a rather clear trend for better treatment effects of more individualized programs. There was no significant difference between various settings. We found significant effects for treatment in the community and in forensic hospitals, but there is not yet sufficient evidence to draw conclusions regarding the effectiveness of sex offender treatment in prisons.The overall methodological quality of the studies was not significantly related to effect size. It should be noted, though, that we could not demonstrate a significant effect on sexual reoffending for the few RCTs in our study pool. Sample size was not linearly related to effect size but small studies with fewer than 50 participants had larger effects. This may suggest publication selection bias. However, studies from unpublished sources did not reveal weaker effects compared to published studies. The strongest methodological moderator was descriptive validity. Most studies lacked a detailed documentation of offender variables so that only few analyses could target this factor. With regard to offender characteristics we found no significant treatment effect for low risk participants. In contrast, medium and higher risk groups benefitted from treatment. Although the treatment of adolescents fared somewhat better than for adults, this difference was not significant. It made no difference whether offenders entered treatment voluntarily or on a mandatory basis.

**Authors&rsquo; conclusions**
Overall, the findings are promising, but there is too much heterogeneity between the results of individual studies to draw a generally positive conclusion about the effectiveness of sex offender treatment. However, the results reveal information that is practically relevant: For example, our review confirms that cognitive-behavioral programs and multi-systemic approaches are more effective than other types of psychosocial interventions. The findings also suggest various conditions of success such as more individualization instead of fully standardized group programs, an advantage of treatment in the community or therapeutic settings instead of prisons, a focus on medium to high risk offenders, early treatment of young sexual offenders, and measures to ensure quality of implementation.Overall, and particularly with regard to moderators, the research base on sex offender treatment is still not yet satisfactory. To enable more definite answers, more high-quality research is needed, particularly outside North America. There is a clear need of more differentiated process and sound outcome evaluations on various types of interventions (including pharmacological treatment), specific characteristics of programs, implementation, settings and participants and research methods.
AU  - Martin,
AU  - S.
AU  - L&ouml;sel,
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /library/sexual-offender-treatment.html
L1  - internal-pdf://2723748455/0050_CCJG_Schmucker_-_Sexual_offender_treatmen.pdf
PY  - 2017
T2  - Campbell Systematic Reviews
TI  - Sexual offender treatment for reducing recidivism among convicted sex offenders
VL  - 13
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Researchers have identified several family-based treatments that hold considerable promise in reducing serious juvenile offending; however, these treatments remain underutilized by youth service systems. In the present study, we used meta-analysis to summarize the findings of research on family-based treatments for serious juvenile offenders. 

**METHOD: **
We conducted a multilevel meta-analysis that modeled dependencies between multiple effect sizes from the same study. The meta-analysis synthesized 324 effect sizes from 28 studies that met inclusion criteria. Potential moderators (e.g., characteristics of samples, treatments, methods, and measures) were entered as fixed effects in the meta-analytic model. 

**RESULTS: **
Across studies, family-based treatments produced modest, yet long-lasting, treatment effects (mean d = 0.25 for antisocial behavior, 0.24 overall) relative to comparison conditions. Furthermore, certain characteristics moderated the magnitude of treatment effects; for example, measures of substance use showed the largest effects and measures of peer relationships showed the smallest effects. 

**CONCLUSIONS: **
Policymakers, administrators, and treatment providers may find it useful to consider the effects of family-based treatments for serious juvenile offenders in their selection of treatments for this population. In addition, investigators who seek to develop and study such treatments may wish to consider the current findings in their future research efforts. 

(PsycINFO Database Record Copyright (c) 2017 APA, all rights reserved).
AN  - 28333535
AU  - Dopp,
AU  - A.
AU  - R.
AU  - Borduin,
AU  - C.
AU  - M.
AU  - White,
AU  - M.
AU  - H.
AU  - Kuppens,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/ccp0000183
L1  - internal-pdf://1259887001/Dopp-2017-Family-based treatments for serious.pdf
PY  - 2017
SP  - 335-354
TI  - Family-based treatments for serious juvenile offenders: A multilevel meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28333535
VL  - 85
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis synthesized findings from studies examining culturally sensitive substance use treatment for racial/ethnic minority youth. 

An extensive literature search located eight eligible studies using experimental or quasi-experimental designs. The meta-analysis quantitatively synthesized findings comparing seven culturally sensitive treatment conditions to seven alternative conditions on samples composed of at least 90% racial/ethnic minority youth. 

The results from the meta-analysis indicated that culturally sensitive treatments were associated with significantly larger reductions in post-treatment substance use levels relative to their comparison conditions (g = 0.37, 95% CI [0.12, 0.62], k = 7, total number participants = 723). The average time between pretest and posttest was 21 weeks (SD = 11.79). There was a statistically significant amount of heterogeneity across the seven studies (Q = 26.5, p = 0.00, tau&lt;sup&gt;2&lt;/sup&gt; = 0.08, I&lt;sup&gt;2&lt;/sup&gt; = 77.4%). 

Differential effects were not statistically significant when contrasts were active generic counterparts of treatment conditions (direct &quot;bona fide&quot; comparisons; g = - 0.08, 95% CI [- 0.51, 0.35]) and &#039;treatment as usual&#039; conditions (g = 0.39, 95% CI [- 0.14, 0.91]). 

Strong conclusions from the review were hindered by the small number of available studies for synthesis, variability in comparison conditions across studies, and lack of diversity in the adolescent clients served in the studies. 

Nonetheless, this review suggests that culturally sensitive treatments offer promise as an effective way to address substance use among racial/ethnic minority youth. 

Copyright &copy; 2017 Elsevier Inc.
AD  - (Steinka-Fry, Tanner-Smith) Vanderbilt University, United States (Dakof) University of Miami Miller School of Medicine, United States (Henderson) Sam Houston State University, United States K.T. Steinka-Fry, Vanderbilt University, Peabody Research Institute, Box 0181 GPC, Nashville, TN 37203-5721, United States. E-mail: k.steinka-fry@vanderbilt.edu
AN  - 614189904
AU  - Steinka-Fry,
AU  - K.
AU  - T.
AU  - Tanner-Smith,
AU  - E.
AU  - E.
AU  - Dakof,
AU  - G.
AU  - A.
AU  - Henderson,
AU  - C.
DA  - 01 Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jsat.2017.01.006
DP  - Ovid Technologies
KW  - Adolescent substance use
KW  - Culturally sensitive treatment
KW  - Meta-analysis
KW  - Racial/ethnic minority youth
KW  - Systematic review
KW  - Treatment effectiveness
KW  - article
KW  - cognitive behavioral therapy
KW  - coping behavior
KW  - cultural diversity
KW  - cultural factor
KW  - cultural sensitivity
KW  - decision making
KW  - effect size
KW  - ethnic group
KW  - human
KW  - meta analysis
KW  - priority journal
KW  - problem solving
KW  - quasi experimental study
KW  - randomized controlled trial (topic)
KW  - sensitivity analysis
KW  - substance abuse
KW  - substance use
KW  - treatment outcome
KW  - treatment planning
KW  - adolescent
KW  - controlled study
KW  - experimental design
KW  - juvenile
KW  - pretest posttest design
KW  - quantitative study
KW  - synthesis
L1  - internal-pdf://0021481421/Steinka-2017-Culturally sensitive substance us.pdf
LA  - English
PY  - 2017
SP  - 22-37
T2  - Journal of Substance Abuse Treatment
TI  - Culturally sensitive substance use treatment for racial/ethnic minority youth: A meta-analytic review
UR  - http://www.elsevier.com/locate/jsathttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=614189904http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jsat.2017.01.006&amp;issn=0740-5472&amp;isbn=&amp;volume=75&amp;issue=&amp;spage=22&amp;pages=22-37&amp;date=2017&amp;title=Journal+of+Substance+Abuse+Treatment&amp;atitle=Culturally+sensitive+substance+use+treatment+for+racial%2Fethnic+minority+youth%3A+A+meta-analytic+review&amp;aulast=Steinka-Fry&amp;pid=%3Cauthor%3ESteinka-Fry+K.T.%3C%2Fauthor%3E%3CAN%3E614189904%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0740547216303014/1-s2.0-S0740547216303014-main.pdf?_tid=5ca09e56-04d0-11e7-8be8-00000aacb35f&amp;acdnat=1489068041_d5941d4a8d071e04aacf08f22a85abb0
VL  - 75
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The literature on the iron requirements of exclusively breastfed infants contains conflicting data and contrary views. 

**OBJECTIVE: **
The purpose of this study was to summarize the evidence for both benefits and risks of daily oral iron supplementation with regard to hematologic, growth, cognitive parameters, and adverse effects in exclusively breastfed infants. 

**MATERIALS AND METHODS: **
Structured electronic searches were conducted using PubMed, Cochrane Library databases, and Google Scholar for randomized controlled trials (RCTs) involving daily iron supplementation in full-term healthy exclusively breastfed infants. Random- and fixed-effects models were used for calculating the pooled estimates. 

**RESULTS: **
Four RCTs with 511 infants were included in the meta-analysis. Iron interventions had no significant effect on iron deficiency or iron deficiency anemia, serum ferritin level, or hemoglobin level. Iron interventions did result in a significant increase in Bayley psychomotor developmental indices in later life (mean difference [MD]=7.00, confidence interval [95% CI] 0.99-13.01) and mean corpuscular volume (MD=2.17 fL; 95% CI 0.99-3.35 fL). Iron supplementation was associated with slower growth during the exclusive breastfeeding period, but the long-term effect is unclear. 

**CONCLUSIONS: **
Limited available evidence suggests that daily iron supplementation has beneficial effects on hematologic parameters and cognitive development, but may delay physical growth in healthy exclusively breastfed infants. There was no evidence to suggest that iron supplementation could cause other adverse effects.
AN  - 28956624
AU  - Cai,
AU  - C.
AU  - Granger,
AU  - M.
AU  - Eck,
AU  - P.
AU  - Friel,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/bfm.2017.0003
L1  - internal-pdf://1329030914/Cai-2017-Effect of Daily Iron Supplementation.pdf
PY  - 2017
SP  - 28
TI  - Effect of Daily Iron Supplementation in Healthy Exclusively Breastfed Infants: A Systematic Review with Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28956624
VL  - 28
ER  -
TY  - JOUR
AB  - **Objective: **
To systematically review the literature reporting outcomes of augmentative family-based treatment (FBT) interventions for adolescents with restrictive eating disorders (EDs). 

**Method: **
Articles were identified through a systematic search of five electronic databases (PsycINFO, MEDLINE, EMBASE, CINAHL, Cochrane Database). 

**Results: **
Thirty articles were included, reporting on FBT augmentations featuring adjunctive treatment components, modified treatment structure and/or content with adherence to FBT principles, and adaptations allowing FBT delivery in different settings. All reported significant improvements in weight and/or ED symptoms at end-of-treatment, although few compared augmentative and standard FBT interventions and good quality follow-up data was generally lacking. 

**Conclusions: **
There is early evidence for the effectiveness of augmentative FBT-based approaches in facilitating weight and/or ED symptom improvements for adolescents with restrictive EDs. There remains a lack of robust evidence demonstrating superior effects of such approaches over standard FBT, and further controlled studies are required to expand on the current evidence. 

Copyright &copy; 2017 John Wiley &amp; Sons, Ltd and Eating Disorders Association.
AN  - 619988954
AU  - Richards,
AU  - I.
AU  - L.
AU  - Subar,
AU  - A.
AU  - Touyz,
AU  - S.
AU  - Rhodes,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/erv.2577
L1  - internal-pdf://1415947171/Richards-2017-Augmentative Approaches in Famil.pdf
PY  - 2017
T2  - European Eating Disorders Review.
TI  - Augmentative Approaches in Family-Based Treatment for Adolescents with Restrictive Eating Disorders: A Systematic Review
UR  - http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1099-0968
UR  - http://onlinelibrary.wiley.com/doi/10.1002/erv.2577/abstract
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering om effektene av tiltaket multisystemisk terapi (MST) i Norge og er en revisjon av en tidligere beskrivelse av det samme tiltaket i Ungsinn (Kornør, 2014). MST er et behandlingsalternativ til institusjonsplassering av ungdom med alvorlige atferdsvansker. Målet med MST er at ungdommene skal redusere antisosial atferd og fremme ansvarlig atferd. Tiltaket er en intensiv, tidsavgrenset og familiebasert behandling for ungdom med atferdsvansker. Det er rettet mot ungdom og deres foresatte, og blir gjennomført i lokalmiljøet hvor aktuelle instanser blir involvert.

METODE
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline, PsykInfo, Norart, Cochrane, Cristin, Nora, Scopus og Swemed. Seks artikler basert på tre nordiske studier tilfredsstilte inklusjonskriteriene for nordiske effektstudier.

RESULTATER
Resultatene omfatter en oppsummering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Det foreligger to norske studier og &eacute;n svensk studie som har undersøkt tiltakets effekt i nordisk kontekst. I den svenske studien og i den første av de to norske studiene ble det benyttet et randomisert kontrollgruppedesign med pre- og posttestmålinger samt oppfølgingsmålinger etter to år. I den andre norske studien ble det undersøkt om effektene vedvarte ved å legge til en ny ikke-randomisert gruppe ungdommer i det andre året av programmet for å sammenligne resultatene fra den tidligere randomiserte kontrollgruppestudien. Den svenske studien rapporterer i tillegg posttestskårer etter 5 år basert på registerdata. Både de norske og den svenske studien sammenlignet MST mot en kontrollgruppe som mottok ordinær behandling i barnevernet. De norske studiene viser til positive effektmål både på kort og lang sikt, mens den svenske studien ikke finner noen signifikante forskjeller mellom gruppen som mottok MST og de som mottok ordinær behandling. Studiene er utført med god kvalitet. Tiltaket har gode rutiner for å kvalitetssikre implementering.

KONKLUSJON
MST klassifiseres på evidensnivå 4 &ndash; Tiltak med tilfredsstillende dokumentasjon på effekt.
AU  - Strøm,
AU  - H.
AU  - K.,
AU  - Handegård,
AU  - B.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2017
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Multisystemisk terapi &ndash; MST (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/multisystemisk-terapi-mst-2-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - We conducted a meta-analysis of single-subject research studies investigating the effectiveness of antecedent strategies grounded in behavioral momentum for improving compliance and on-task performance for students with autism. 

First, we assessed the research rigor of those studies meeting our inclusionary criteria. Next, in order to apply a universal metric to help determine the effectiveness of this category of antecedent strategies investigated via single-subject research methods, we calculated effect sizes via omnibus improvement rate differences (IRDs). 

Outcomes provide additional support for behavioral momentum, especially interventions incorporating the high-probability command sequence. Implications for research and practice are discussed, including the consideration of how single-subject research is systematically reviewed to assess the rigor of studies and assist in determining overall intervention effectiveness . 

Copyright &copy; 2017 Springer Science+Business Media New York
AN  - 614574238
AU  - Cowan,
AU  - R.
AU  - J.
AU  - Abel,
AU  - L.
AU  - Candel,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10803-017-3076-6
L1  - internal-pdf://2707271838/Cowan-2017-A Meta-Analysis of Single-Subject R.pdf
PY  - 2017
SP  - 1-14
TI  - A Meta-Analysis of Single-Subject Research on Behavioral Momentum to Enhance Success in Students with Autism
UR  - http://www.wkap.nl/journalhome.htm/0162-3257
ER  -
TY  - JOUR
AB  - **Objective: **
While a number of articles have reviewed the use of long-acting injectable antipsychotics (LAIs) in first-episode psychosis, there has been extremely limited focus on LAIs in children and adolescents. This review of the literature evaluated use of LAIs in children and youth under the age of 18. 

**Methods:** 
We conducted a comprehensive search of the PubMed, PsychINFO, CINAHL, and EMBASE databases using keywords related to LAIs, children, and psychiatric conditions, including schizophrenia, bipolar disorder, and schizoaffective disorder. Reports were included if they were in English, conducted between 1971 and 2015, and reported on use of LAIs in individuals less than the age of 18. 

**Results: **
The search identified seven reports including one open-label trial, three case reports, and three case series. No controlled trials were found. Sample sizes ranged from 1 to 19 with a total of 36 individuals in all cases combined. Mean sample age was 12.1 +/- 2.2 in the open-label trial and calculated to be 14.9 +/- 1.5 in the remainder of the reports. Most patients (80.6%) were boys. Primary diagnoses included bipolar I disorder (n = 18; 50%), schizophrenia (n = 7; 19.4%), and bipolar spectrum disorders (n = 6; 16.6%). The LAIs used were risperidone long-acting injection (n = 24; 66.7%), paliperidone palmitate (n = 8; 22.2%), fluphenazine decanoate (n = 1; 2.8%), aripiprazole extended-release injectable (n = 1; 2.8%), zuclopenthixol decanoate (n = 1; 2.8%), and olanzapine extended release (n = 1; 2.8%). Most cases reported clinical improvement and the majority of individuals (n = 14; 82.4%) were reported to tolerate the medication well. The most common side effects were weight gain (mean 5.7 +/- 4.1 kg in the open-label trial), tremor (n = 2; 5.6%), and oculogyric crisis (n = 2; 5.6%). 

**Conclusions: **
This literature review suggests that LAI use in youth with serious mental illness may improve clinical outcomes and adherence. Side effects of LAIs among youth appear are similar to oral preparations. However, there is a paucity of data despite issues with nonadherence in youth and the fact that they have much to lose and much to gain. Existing reports have substantial methodological limitations, and research is needed to guide the use of LAIs in children and adolescents. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-08181-002
AU  - Lytle,
AU  - S.
AU  - McVoy,
AU  - M.
AU  - Sajatovic,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/cap.2016.0055
L1  - internal-pdf://0961214910/Lytle-2017-Long-acting injectable antipsychoti.pdf
PY  - 2017
SP  - 2-9
TI  - Long-acting injectable antipsychotics in children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-08181-002
VL  - 27
ER  -
TY  - JOUR
AB  - **Background: **
Epidemiological studies have demonstrated that folate, iodine and iron intake during pregnancy impacts on foetal brain development and cognitive function. However, in human studies, the relationship with other dietary nutrients is less clear. 

**Objective: **
This systematic review aims to critically appraise the current literature and meta-analyses results from nutritional interventions during pregnancy that aimed to optimise infant and child cognitive outcomes. 

**Design: **
Ten electronic databases were searched for articles published up to August 2017. The search was limited to articles published in English. Randomised controlled trials (RCTs) testing the impact of any nutritional intervention (dietary counselling, education, nutrient supplementation, fortified foods and/or foods) during pregnancy on cognitive outcomes of children (&lt;10 years old). Two independent reviewers assessed study eligibility and quality using the American Dietetic Association quality criteria checklist for primary research. Standardised mean differences were used for nine cognitive domains to measure effects for meta-analyses. 

**Results: **
A total of 34 RCTs were included (21 studies included children aged less than 35 months, 10 studies included children aged 36-60 months and 3 studies included children aged 61-119 months). The types of nutritional interventions included nutrient supplements, whole foods, fortified foods and nutrition education. The following nine cognition outcomes: attention, behaviour, crystallised intelligence, fluid intelligence, global cognition, memory, motor skills, visual processing, and problem solving were not significantly impacted by nutritional interventions, although 65% of studies conducted post-hoc data analyses and were likely to be underpowered. Although, long chain polyunsaturated fatty acids (LCPUFA) supplementation was associated with a marginal increase in crystallised intelligence (Effect size (ES): 0.25; 95% confidence interval (95% CI): -0.04, 0.53), the effect was not statistically significant (p = 0.09), with significant study heterogeneity (p = 0.00). 

**Conclusions: **
LCPUFA supplementation may be associated with an improvement in child crystallised intelligence, however further research is warranted. The remaining eight cognition domains were not significantly impacted by maternal nutritional interventions.
AN  - WOS:000416547200103
AU  - Taylor,
AU  - R.
AU  - M.
AU  - Fealy,
AU  - S.
AU  - M.
AU  - Bisquera,
AU  - A.
AU  - Smith,
AU  - R.
AU  - Collins,
AU  - C.
AU  - E.
AU  - Evans,
AU  - T.
AU  - J.
AU  - Hure,
AU  - A.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3390/nu9111265
L1  - internal-pdf://3951993108/Taylor-2017-Effects of Nutritional Interventio.pdf
PY  - 2017
SP  - 32
T2  - Nutrients
TI  - Effects of Nutritional Interventions during Pregnancy on Infant and Child Cognitive Outcomes: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000416547200103
UR  - http://www.mdpi.com/2072-6643/9/11/1265/pdf
VL  - 9
ER  -
TY  - JOUR
AB  - The growing mental health needs of students within schools have resulted in teachers increasing their involvement in the delivery of school-based, psychosocial interventions. 

Current research reports mixed findings concerning the effectiveness of psychosocial interventions delivered by teachers for mental health outcomes. This article presents a systematic review and meta-analysis that examined the effectiveness of school-based psychosocial interventions delivered by teachers on internalizing and externalizing outcomes and the moderating factors that influence treatment effects on these outcomes. 

Nine electronic databases, major journals, and gray literature (e.g., websites, conference abstract) were searched and field experts were contacted to locate additional studies. Twenty-four studies that met the study inclusion criteria were coded into internalizing or externalizing outcomes and further analyzed using robust variance estimation in meta-regression. Both publication and risk of bias of studies were further assessed. 

The results showed statistically significant reductions in students&#039; internalizing outcomes (d = .133, 95% CI [.002, .263]) and no statistical significant effect for externalizing outcomes (d = .15, 95% CI [-.037, .066]). Moderator analysis with meta-regression revealed that gender (%male, b = -.017, p &lt; .05), race (% Caucasian, b = .002, p &lt; .05), and the tier of intervention (b = .299, p = .06) affected intervention effectiveness. 

This study builds on existing literature that shows that teacher-delivered Tier 1 interventions are effective interventions but also adds to this literature by showing that interventions are more effective with internalizing outcomes than on the externalizing outcomes. Moderator analysis also revealed treatments were more effective with female students for internalizing outcomes and more effective with Caucasian students for externalizing outcomes.
AN  - 28493176
AU  - Franklin,
AU  - C.
AU  - Kim,
AU  - J.
AU  - S.
AU  - Beretvas,
AU  - T.
AU  - S.
AU  - Zhang,
AU  - A.
AU  - Guz,
AU  - S.
AU  - Park,
AU  - S.
AU  - Montgomery,
AU  - K.
AU  - Chung,
AU  - S.
AU  - Maynard,
AU  - B.
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-017-0235-4
L1  - internal-pdf://1067725902/Franklin-2017-The Effectiveness of Psychosocia.pdf
PY  - 2017
SP  - 333-350
TI  - The Effectiveness of Psychosocial Interventions Delivered by Teachers in Schools: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28493176
VL  - 20
ER  -
TY  - JOUR
AB  - Background: 
Our study is an analysis of multiple publications involving assessing the comparable efficacy and tolerability of six interventions, which are lisdexamfetamine dimesylate (LDX), atomoxetine (ATX), methylphenidate (MPH), clonidine hydrochloride (CLON), guanfacine extended release (GXR), and bupropion, for young patients (6-18years old) suffering from attention deficit hyperactivity disorder (ADHD). 

Methods:
A conventional meta-analysis (MA) was performed to give direct comparisons and a network meta-analysis (NMA) was used to show the combination of direct and indirect evidence. Ranking preference for all the interventions under a certain outcome was given by the surface of cumulative ranking curve area (SUCRA). 

Results: 
Overall, 15,025 participants from 73 studies were involved in our analysis. In the pairwise MA, LDX was associated with less withdrawal than ATX for lack of efficacy. MPH showed less effectiveness than LDX according to ADHD Rating Scale score. Based on the analysis of our NMA, significant results of efficacy that LDX is a competitive drug were observed when evaluating LDX in comparison with other drugs except for CLON. ATX and GXR presented higher rates of abdominal pain morbidity versus inactive treatment. 

Conclusion: 
The stimulants LDX and MPH are still highly recommended because they are highly effective and are tolerated well by patients. Among the non-stimulants, CLON can be taken into consideration for its appreciable effectiveness and tolerability. ATX and GXR can be seen as moderate choices.
AN  - 29180967
AU  - Luan,
AU  - R.
AU  - Mu,
AU  - Z.
AU  - Yue,
AU  - F.
AU  - He,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3389/fpsyt.2017.00229
L1  - internal-pdf://3111255040/Luan-2017-Efficacy and Tolerability of Differe.pdf
PY  - 2017
SP  - 229
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Efficacy and Tolerability of Different Interventions in Children and Adolescents with Attention Deficit Hyperactivity Disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29180967
VL  - 8
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Insufficient sleep among students is a major school health problem. School-based sleep education programs tailored to reach large number of students may be one of the solutions. A systematic review and meta-analysis was conducted to summarize the programs&#039; effectiveness and current status.

**METHODS: **
Electronic databases were searched up until May 2015. Randomized controlled trials of school-based sleep intervention among 10- to 19-year-old students with outcome on total sleep duration were included. Methodological quality of the studies was assessed using the Cochrane&#039;s risk of bias assessment. 

**RESULTS: **
Seven studies were included, involving 1876 students receiving sleep education programs and 2483 attending classes-as-usual. Four weekly 50-minute sleep education classes were most commonly provided. Methodological quality was only moderate, with a high or an uncertain risk of bias in several domains. Compared to classes-as-usual, sleep education programs produced significantly longer weekday and weekend total sleep time and better mood among students at immediate post-treatment, but the improvements were not maintained at follow-up. 

**CONCLUSIONS: **
Limited by the small number of studies and methodological limitations, the preliminary data showed that school-based sleep education programs produced short-term benefits. Future studies should explore integrating sleep education with delayed school start time or other more effective approaches.
AN  - 28463450
AU  - Chung,
AU  - K.
AU  - F.
AU  - Chan,
AU  - M.
AU  - S.
AU  - Lam,
AU  - Y.
AU  - Y.
AU  - Lai,
AU  - C.
AU  - S.
AU  - Yeung,
AU  - W.
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/josh.12509
L1  - internal-pdf://4162055209/Chung-2017-School-Based Sleep Education Progra.pdf
PY  - 2017
SP  - 401-408
T2  - Journal of School Health
TI  - School-Based Sleep Education Programs for Short Sleep Duration in Adolescents: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=28463450
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1111/josh.12509
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/josh.12509
VL  - 87
ER  -
TY  - JOUR
AB  - The adoption of methods and strategies validated through rigorous, experimentally oriented research is a core professional value of special education. We conducted a systematic review and meta-analysis examining the experimental literature on Technology-Aided Instruction and Intervention (TAII) using research identified as part of the National Autism Professional Development Project. 

We applied novel between-case effect size methods to the TAII single-case research base. In addition, we used meta-analytic methodologies to examine the methodological quality of the research, calculate average effect sizes to quantify the level of evidence for TAII, and compare effect sizes across single-case and group-based experimental research. 

Results identified one category of TAII-computer-assisted instruction-as an evidence-based practice across both single-case and group studies. The remaining two categories of TAII-augmentative and alternative communication and virtual reality-were not identified as evidence-based using What Works Clearinghouse summary ratings. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-51755-004
AU  - Barton,
AU  - E.
AU  - E.
AU  - Pustejovsky,
AU  - J.
AU  - E.
AU  - Maggin,
AU  - D.
AU  - M.
AU  - Reichow,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0741932517729508
L1  - internal-pdf://4081232627/Barton-2017-Technology-aided instruction and i.pdf
PY  - 2017
SP  - 371-386
T2  - Remedial and Special Education
TI  - Technology-aided instruction and intervention for students with ASD: A meta-analysis using novel methods of estimating effect sizes for single-case research
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2017-51755-004
UR  - http://journals.sagepub.com/doi/pdf/10.1177/0741932517729508
VL  - 38
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis evaluates the efficacy of parent training group interventions to treat child externalizing and/or internalizing problems. 

A search identified 21 randomized controlled trials of parent group interventions aimed at ameliorating child externalizing and/or internalizing problems in children aged 4-12 years. Random effects meta-analyses yielded significant pooled treatment effect size (g) estimates for child externalizing (g=-0.38) and internalizing problems (g=-0.18). 

Child anxiety symptoms or internalizing problems evident in children with externalizing behavior problems did not change significantly following intervention. Study quality was a statistically significant moderator of treatment response for child externalizing problems, however hours of planned parent group treatment and treatment recipient were not. 

Findings support the use of parent group interventions as an effective treatment for reducing externalizing problems in children aged 4-12 years. Whilst statistically significant, programs had a limited impact on internalizing symptoms, indicating a need for further investigation.
AN  - 28699101
AU  - Buchanan-Pascall,
AU  - S.
AU  - Gray,
AU  - K.
AU  - M.
AU  - Gordon,
AU  - M.
AU  - Melvin,
AU  - G.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10578-017-0745-9
L1  - internal-pdf://2046951960/Buchanan-Pascal-2017-Systematic Review and Met.pdf
PY  - 2017
SP  - 11
TI  - Systematic Review and Meta-analysis of Parent Group Interventions for Primary School Children Aged 4-12 Years with Externalizing and/or Internalizing Problems
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28699101
VL  - 11
ER  -
TY  - JOUR
AB  - **Background: **
Pregnancies with pre-existing diabetes are high risk, with increased risk of poorer fetal, neonatal, and maternal outcomes. Identifying interventions to improving health outcomes for women with diabetes and their infants is a priority, as rates of diabetes continue to increase. Exercise has been shown to have benefits for non-pregnant individuals with pre-existing type 2 diabetes, such as improving glycaemic control, and reducing visceral adipose tissue and plasma triglycerides. For pregnant women with pre-existing diabetes, the effects of exercise interventions on the mother and her baby are unknown. An earlier Cochrane review on &#039;Exercise for pregnant women with diabetes&#039; considered both pre-existing diabetes and gestational diabetes. That Cochrane review has now been split into two new reviews (following new protocols) - one on gestational diabetes and one on pre-existing diabetes (this review). 

**Objectives: **
To evaluate the effects of exercise interventions for improving maternal and fetal outcomes in women with pre-existing diabetes. Search methods: We searched Cochrane Pregnancy and Childbirth&rsquo;s Trials Register, ClinicalTrials.gov, and the WHO International Clinical Trials Registry Platform (ICTRP) on 27 June 2017, and reference lists of retrieved studies. 

**Selection criteria: **
We had planned to include published or unpublished randomised controlled trials (RCT) or cluster-randomised trials, in full text or abstract format that compared any type of exercise programme, added to standard care, targeted at women with known pre-gestational diabetes (type 1 or type 2 diabetes), at any stage of pregnancy, compared with 1) standard care alone or 2) standard care plus another exercise intervention. Quasi-randomised and cross-over trials were excluded. Conference abstracts were handled in the same way as full-text publications. Women with gestational diabetes mellitus were excluded, as they were covered in a separate Cochrane review. 

**Data collection and analysis: **
We had planned that two review authors would independently assess all the potential studies we identified as a result of the search strategy. For eligible studies, two review authors would have independently extracted the data using an agreed form. We had planned to resolve discrepancies through discussion, or by consulting a third person. We also had planned to assess the evidence using the GRADE approach. Main results: We did not identify any randomised controlled trials. 

**Authors&#039; conclusions: **
There was no evidence from RCTs that evaluated the effects of exercise interventions for improving maternal and fetal outcomes in women with pre-existing diabetes. Good quality, large randomised controlled trials are urgently needed to identify exercise interventions that are safe, and improve health outcomes for women with pre-existing diabetes and their babies. Future studies in this area could utilise the standardised outcomes in this review, in order to improve consistency between trials in this area, and aid future meta-analysis.
AN  - CD012696
AU  - Brown,
AU  - J.
AU  - Ceysens,
AU  - G.
AU  - Boulvain,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD012696.pub2
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Pregnancy[checkword]
KW  - Exercise
KW  - Pregnancy in Diabetics
PY  - 2017
T2  - Cochrane Database of Systematic Reviews
TI  - Exercise for pregnant women with pre-existing diabetes for improving maternal and fetal outcomes
UR  - http://dx.doi.org/10.1002/14651858.CD012696.pub2
ER  -
TY  - JOUR
AB  - **Background: **
Disorganised attachment patterns in infants have been linked to later psychopathology. Services have variable practices for identifying and providing interventions for families of children with disorganised attachment patterns, which is the attachment pattern leading to most future psychopathology. Several recent government reports have highlighted the need for better parenting interventions in at risk groups. 

**Objectives: **
The objective of this review and meta-analysis was to evaluate the clinical effectiveness of available parenting interventions for families of children at high risk of developing, or already showing, a disorganised pattern of attachment. 

**Methods: **
Population: Studies were included if they involved parents or caregivers of young children with a mean age under 13 years who had a disorganised classification of attachment or were identified as at high risk of developing such problems. Included interventions were aimed at parents or caregivers (e.g. foster carers) seeking to improve attachment. Comparators included an alternative intervention, an attention control, treatment as usual or no intervention. The primary outcome was a disorganised pattern in childhood measured using a validated attachment instrument. Studies that did not use a true Randomised Controlled Trial (RCT) design were excluded from the review. Both published and unpublished papers were included, there were no restrictions on years since publication and foreign language papers were included where translation services could be accessed within necessary timescales. 

**Results: **
A comprehensive search of relevant databases yielded 15,298 papers. This paper reports a systematic review as part of an NIHR HTA study identifying studies pre-2012, updated to include all papers to October 2016. Two independent reviewers undertook two stage screening and data extraction of the included studies at all stages. A Cochrane quality assessment was carried out to assess the risk of bias. In total, fourteen studies were included in the review. In a meta-analysis of these fourteen studies the interventions saw less disorganised attachment at outcome compared to the control (OR = 0.50, (0.32, 0.77), p = 0.008). The majority of the interventions targeted maternal sensitivity. We carried out exploratory analyses to examine factors that may influence treatment outcome but these should be treated with caution given that we were limited by small numbers of studies. 

**Conclusions: **
Parenting interventions that target parental sensitivity show promise in reducing disorganised attachment. This is limited by few high quality studies and the fact that most studies are with mothers. More high quality randomised controlled trials are required to elucidate this further. 

Copyright &copy; 2017 Wright et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AN  - 617302124
AU  - Wright,
AU  - B.
AU  - Hackney,
AU  - L.
AU  - Hughes,
AU  - E.
AU  - Barry,
AU  - M.
AU  - Glaser,
AU  - D.
AU  - Prior,
AU  - V.
AU  - Allgar,
AU  - V.
AU  - Marshall,
AU  - D.
AU  - Barrow,
AU  - J.
AU  - Kirby,
AU  - N.
AU  - Garside,
AU  - M.
AU  - Kaushal,
AU  - P.
AU  - Perry,
AU  - A.
AU  - McMillan,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0180858
L1  - internal-pdf://2962963187/Wright-2017-Decreasing rates of disorganised a.pdf
PY  - 2017
TI  - Decreasing rates of disorganised attachment in infants and young children, who are at risk of developing, or who already have disorganised attachment. A systematic review and meta-analysis of early parenting interventions
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0180858&amp;type=printable
VL  - 12 (7) (no pagination)
ER  -
TY  - JOUR
AB  - **PURPOSE **
Although evidence exists for the efficacy of psychosocial interventions to prevent the onset of depression, little is known about its prevention in primary care. We aimed to evaluate the effectiveness of psychological and educational interventions to prevent depression in primary care. 

**METHODS **
We conducted a systematic review and meta-analysis of relevant randomized controlled trials (RCTs) examining the effect of psychological and educational interventions to prevent depression in nondepressed primary care attendees. We searched MEDLINE, PsycINFO, Web of Science, OpenGrey Repository, Cochrane Central Register of Controlled Trials, and other sources up to May 2016. At least 2 reviewers independently evaluated the eligibility criteria, extracted data, and assessed the risk of bias. We calculated standardized mean differences (SMD) using random-effects models. 

**RESULTS **
We selected 14 studies (7,365 patients) that met the inclusion criteria, 13 of which were valid to perform a meta-analysis. Most of the interventions had a cognitive-behavioral orientation, and in only 4 RCTs were the intervention clinicians primary care staff. The pooled SMD was -0.163 (95% CI, -0.256 to -0.070; P = .001). The risk of bias and the heterogeneity (I-2 = 20.6%) were low, and there was no evidence of publication bias. Meta-regression detected no association between SMD and follow-up times or SMD and risk of bias. Subgroup analysis suggested greater effectiveness when the RCTs used care as usual as the comparator compared with those using placebo. 

**CONCLUSIONS**
Psychological and educational interventions to prevent depression had a modest though statistically significant preventive effect in primary care. Further RCTs using placebo or active comparators are needed.
AN  - WOS:000402477900012
AU  - Conejo-Ceron,
AU  - S.
AU  - Moreno-Peral,
AU  - P.
AU  - Rodriguez-Morejon,
AU  - A.
AU  - Motrico,
AU  - E.
AU  - Navas-Campana,
AU  - D.
AU  - Rigabert,
AU  - A.
AU  - Martin-Perez,
AU  - C.
AU  - Rodriguez-Bayon,
AU  - A.
AU  - Ballesta-Rodriguez,
AU  - M.
AU  - I.
AU  - Luna,
AU  - J.
AU  - D.
AU  - Garcia-Campayo,
AU  - J.
AU  - Roca,
AU  - M.
AU  - Bellon,
AU  - J.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1370/afm.2031
L1  - internal-pdf://3872291567/Conejo-Ceron-2017-Effectiveness of Psychologic.pdf
PY  - 2017
SP  - 262-271
TI  - Effectiveness of Psychological and Educational Interventions to Prevent Depression in Primary Care: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000402477900012
VL  - 15
ER  -
TY  - JOUR
AB  - **Objective: **
To evaluate the long-term effects of methylphenidate imediate-release (MPH-IR), and to confirm the efficacy established in previous meta-analyses of short-term studies. 

**Method: **
Published and unpublished studies in which participants were treated with MPH-IR for 12 weeks or more were searched. Pooled effect sizes from these studies were computed with the DerSimonian and Laird random-effect model. Meta-regression analysis was conducted to estimate covariates associated with treatment effects. 

**Results: **
Seven studies were included. Pooled parents ratings for inattention and hyperactivity/impulsivity resulted in standardized mean difference (SMD) = 0.96 (95% confidence interval [CI] = [0.60, 1.32]) and SMD = 1.12 (95% CI = [0.85, 1.39]), respectively; pooled teachers ratings showed SMD = 0.98 (95% CI = [0.09, 1.86]) for inattention and SMD = 1.25 (95% CI = [0.7, 1.81]) for hyperactivity/impulsivity. No evidence of association of any covariates with treatment effect was detected in the meta-regression. 

**Conclusion: **
MPH-IR is efficacious for childhood ADHD for periods longer than 12 weeks.
AD  - [Moreira Maia, Carlos Renato; Caye, Arthur; Polanczyk, Carisi Anne; Paim Rohde, Luis Augusto] Univ Fed Rio Grande do Sul, Porto Alegre, RS, Brazil. [Cortese, Samuele] Cambridge Univ Hosp NHS Fdn Trust, Nottingham, England. [Deakin, Thomas Kuhn] Hosp Clin Porto Alegre, ADHD Outpatient Program, Porto Alegre, RS, Brazil. [Polanczyk, Guilherme Vanoni] Univ Sao Paulo, Sch Med, BR-05508 Sao Paulo, Brazil. Maia, CRM (reprint author), Univ Fed Rio Grande do Sul, ADHD Outpatient Program, Hosp Clin Porto Alegre, Rua Ramiro Barcelos 2350, BR-90035003 Porto Alegre, RS, Brazil. crm.maia@gmail.com
AN  - WOS:000391783800001
AU  - Maia,
AU  - C.
AU  - R.
AU  - M.
AU  - Cortese,
AU  - S.
AU  - Caye,
AU  - A.
AU  - Deakin,
AU  - T.
AU  - K.
AU  - Polanczyk,
AU  - G.
AU  - V.
AU  - Polanczyk,
AU  - C.
AU  - A.
AU  - Rohde,
AU  - L.
AU  - A..
AU  - P.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 0.1177/1087054714559643
J2  - J. Atten. Disord.
KW  - ADHD
KW  - methylphenidate
KW  - meta-analysis
KW  - review
KW  - ADHD
KW  - deficit hyperactivity disorder
KW  - attention-deficit/hyperactivity
KW  - disorder
KW  - critical-appraisal
KW  - clinical-trials
KW  - double-blind
KW  - children
KW  - medications
KW  - adolescents
KW  - prevalence
KW  - diagnosis
KW  - Psychology
KW  - Psychiatry
L1  - internal-pdf://2693227522/Maia-2017-Long-Term Efficacy of Methylphenidat.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: EH5AA Times Cited: 3 Cited Reference Count: 66 Moreira Maia, Carlos Renato Cortese, Samuele Caye, Arthur Deakin, Thomas Kuhn Polanczyk, Guilherme Vanoni Polanczyk, Carisi Anne Paim Rohde, Luis Augusto National Council for Scientific and Technological Development (CNPq, Brazil) [067/2009] The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was partially supported by research grants from National Council for Scientific and Technological Development (CNPq, Brazil; Edital MCT/CNPq/CT-Saude/MS/SCTIE/DECIT No 067/2009) [Bolsa de Produtividade em Pesquisa to G.V.P., L.A.P.R.], and Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, Brazil. 3 Sage publications inc Thousand oaks 1557-1246
PY  - 2017
SP  - 3-13
T2  - Journal of Attention Disorders
TI  - Long-Term Efficacy of Methylphenidate Immediate-Release for the Treatment of Childhood ADHD: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000391783800001
VL  - 21
ER  -
TY  - JOUR
AB  - **Objective: **
To systematically review digitally assisted parent training programs (DPTs) targeting the treatment of children and adolescents with disruptive behaviors. 

**Data Sources: **
A search was conducted using PubMed, PsycINFO, and EMBASE databases for peer-reviewed studies published between January 1, 2000, and March 1, 2016. Reference lists of included and review articles were searched manually for additional references. 

**Study Selection:** 
Broad search terms in varying combinations for parent, training, technologies, and disruptive behavior problems were used. We included English-language articles reporting on the effectiveness of DPTs targeting child or adolescent disruptive behaviors (eg, conduct disorder, oppositional defiant disorder). DPTs designed to use digital media or software programs not to be primarily used within a therapy setting (eg, group, face-to-face) were included. 

**Data Extraction: **
Study design, recruitment and sample characteristics, theoretical background, digital program features, user&#039;s engagement, and measures of child behavior were extracted.

**Results: **
Fourteen intervention studies (n = 2, 427, 58% male, 1, 500 in DPT conditions, 12 randomized trials) examining 10 programs met inclusion criteria. Interventions included self-directed noninteractive (eg, podcasts; 3 studies) and interactive (eg, online software; 4 studies) DPTs, remotely administered DPTs combined with professional phone-based coaching (2 studies), and a smartphone enhancement of standard treatment. Interventions were delivered over a mean +/- SD period of 8.7 +/- 4.2 weeks, most (11/14; 78.6%) were remotely administered, and all recruitment procedures included an outreach for parents outside of mental health-care settings. For programs with &gt; 5 sessions, the mean +/- SD completion rate of available sessions was 68.6% +/- 13.1%. In comparison to no treatment control, self-directed programs yielded significant improvements in child behavior for children (age &lt; 9 years, Cohend = 0.47-0.80, 4 studies) and adolescents (d = 0.17, 0.20, 2 studies). Overall, reduced professional support combined with DPT was not inferior to full-contact conditions and showed small improvement in comparison to usual care (d = 0.34). Preliminary indicators also suggested that technology enhancements may increase engagement and outcomes of standard treatment. 

**Conclusions: **
The current review indicates the efficacy of DPT across a range of therapy formats applied in real-world settings demonstrating the potential for increased accessibility of evidence-based treatment for youth with disruptive behaviors. Additional studies are needed to extend these findings and to determine moderating effects of different designs. 

&copy; Copyright 2017 Physicians Postgraduate Press, Inc.
AN  - 619051042
AU  - Baumel,
AU  - A.
AU  - Pawar,
AU  - A.
AU  - Mathur,
AU  - N.
AU  - Kane,
AU  - J.
AU  - M.
AU  - Correll,
AU  - C.
AU  - U.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4088/JCP.16r11063
L1  - internal-pdf://3410402575/Baumel-2017-Technology-assisted parent trainin.pdf
PY  - 2017
SP  - e957-e969
T2  - Journal of Clinical Psychiatry
TI  - Technology-assisted parent training programs for children and adolescents with disruptive behaviors: A Systematic Review
UR  - http://www.psychiatrist.com/JCP/article/_layouts/ppp.psych.controls/BinaryViewer.ashx?Article=/JCP/article/Pages/2017/v78n08/16r11063.aspx&amp;Type=Article
VL  - 78
ER  -
TY  - JOUR
AB  - A review of meta-analyses of cognitive-behavioral therapy (CBT) for childhood anxiety and depression was conducted. A total of 36 meta-analyses were identified that met inclusion criteria for this review. 

In most cases, medium-to-large effect sizes for treatment reduction were observed when CBT was compared to non-active control conditions. Small-to-medium effects were observed when CBT was compared to active control treatments. 

The available meta-analyses generally did not examine, or data were not sufficient to evaluate, potential moderators of outcome, differential effects for parental involvement, or changes in quality of life or functional outcomes associated with treatment. 

Accordingly, while CBT should be broadly considered an effective treatment approach for childhood anxiety and depression, additional research is warranted in order to establish guidelines for service delivery for complicating factors in client presentation. 

Copyright &copy; 2017 Elsevier Ltd
AN  - 615709852
AU  - Crowe,
AU  - K.
AU  - McKay,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.janxdis.2017.04.001
L1  - internal-pdf://2966399685/Crowe-2017-Efficacy of cognitive-behavioral th.pdf
PY  - 2017
SP  - 76-87
TI  - Efficacy of cognitive-behavioral therapy for childhood anxiety and depression
UR  - http://www.elsevier.com/inca/publications/store/8/0/1
VL  - 49
ER  -
TY  - JOUR
AB  - Aim: 
Oxytocin presents an exciting potential to target the core symptoms of autism spectrum disorder (ASD) pharmacologically in an easily administered, cost-effective form with possibly minimal adverse effects. But, there are still major gaps in this area of research. This paper reviewed randomized controlled trials (RCTs) examining the effects of oxytocin administration on social cognition and restricted, repetitive behaviors in individuals with an ASD. 

Method: 
Electronic literature searches were conducted from PsycINFO, PubMed, Web of Knowledge, and EMBASE for RCTs published through June 2015. 

Results: 
12 RCTs were included in this review. 7 out of the 11 studies that examined social cognition reported improvements. Additionally, one out of the 4 studies on restricted, repetitive behaviors, reported improvements following oxytocin administration. However, results from our meta-analyses suggest that oxytocin has no significant effect on these 2 domains. 

Conclusion: 
Previous evidence revealed mixed findings about the effects of oxytocin on ASD. Given the limited number of RCTs, our summary of findings on the effectiveness of oxytocin on ASD should still be considered tentative.
AN  - WOS:000393906600003
AU  - Ooi,
AU  - Y.
AU  - P.
AU  - Weng,
AU  - S.
AU  - J.
AU  - Kossowsky,
AU  - J.
AU  - Gerger,
AU  - H.
AU  - Sung,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1055/s-0042-109400
L1  - internal-pdf://0538231729/Ooi-2017-Oxytocin and Autism Spectrum Disorder.pdf
PY  - 2017
SP  - 9
TI  - Oxytocin and Autism Spectrum Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - &lt;Go to ISI&gt;://WOS:000393906600003
VL  - 50
ER  -
TY  - JOUR
AB  - **Background:**
Children and adolescents with conduct disorder (CD) show repetitive and persistent patterns of aggressive behaviour and the more severe forms are often associated with callous-unemotional (CU) traits. 

**Objectives: **
To systematically review and, where data are adequate, conduct meta-analyses on the efficacy of medication on aggression in children and adolescent with CD considering the impact of CU traits. 

**Results: **
Few studies have investigated patients with CD as primary diagnosis, and few of these have discriminated between different types of aggression or reported measures of CU traits. Methylphenidate and risperidone showed the largest effects on aggression in randomized controlled trials; other antipsychotics showed clinical efficacy on CD but this evidence is mainly revealed by open label trials. There is some low quality evidence to support a small effect of mood stabilizers and other agents. There were only two papers describing the effects of CU traits thus providing inconclusive results. 

**Conclusion: **
Considering heterogeneity of the disorder, more proof-of-concept clinical studies are needed to define effects of medication and role of CU traits. 

Copyright &copy; 2017.
AN  - 614729436
AU  - Balia,
AU  - C.
AU  - Carucci,
AU  - S.
AU  - Coghill,
AU  - D.
AU  - Zuddas,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.neubiorev.2017.01.024
L1  - internal-pdf://3006965361/Balia-2017-The pharmacological treatment of ag.pdf
PY  - 2017
TI  - The pharmacological treatment of aggression in children and adolescents with conduct disorder. Do callous-unemotional traits modulate the efficacy of medication?
UR  - http://www.elsevier.com/locate/neubiorev
VL  - 14
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
Infancy is a critical stage of life, and a secure relationship with caring and responsive caregivers is crucial for healthy infant development. Early parenting interventions aim to support families in which infants are at risk of developmental harm. Our objective is to systematically review the effects of parenting interventions on child development and on parent-child relationship for at-risk families with infants aged 0-12 months. 

**DESIGN: **
This is a systematic review and meta-analyses. We extracted publications from 10 databases in June 2013, January 2015 and June 2016, and supplemented with grey literature and hand search. We assessed risk of bias, calculated effect sizes and conducted meta-analyses. 

**INCLUSION CRITERIA: **
(1) Randomised controlled trials of structured psychosocial interventions offered to at-risk families with infants aged 0-12 months in Western Organisation for Economic Co-operation and Development (OECD) countries, (2) interventions with a minimum of three sessions and at least half of these delivered postnatally and (3) outcomes reported for child development or parent-child relationship. 

**RESULTS: **
Sixteen studies were included. Meta-analyses were conducted on seven outcomes represented in 13 studies. Parenting interventions significantly improved child behaviour (d=0.14; 95%CI 0.03 to 0.26), parent-child relationship (d=0.44; 95%CI 0.09 to 0.80) and maternal sensitivity (d=0.46; 95%CI 0.26 to 0.65) postintervention. There were no significant effects on cognitive development (d=0.13; 95%CI -0.08 to 0.41), internalising behaviour (d=0.16; 95%CI -0.03 to 0.33) or externalising behaviour (d=0.16; 95%CI -0.01 to 0.30) post-intervention. At long-term follow-up we found no significant effect on child behaviour (d=0.15; 95%CI -0.03 to 0.31). 

**CONCLUSIONS: **
Interventions offered to at-risk families in the first year of the child&#039;s life appear to improve child behaviour, parent-child relationship and maternal sensitivity post-intervention, but not child cognitive development and internalising or externalising behaviour. Future studies should incorporate follow-up assessments to examine long-term effects of early interventions.
AN  - 29284713
AU  - Rayce,
AU  - S.
AU  - B.
AU  - Rasmussen,
AU  - I.
AU  - S.
AU  - Klest,
AU  - S.
AU  - K.
AU  - Patras,
AU  - J.
AU  - Pontoppidan,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmjopen-2016-015707
L1  - internal-pdf://2201069184/Rayce-2017-Effects of parenting interventions.pdf
PY  - 2017
SP  - e015707
T2  - BMJ Open
TI  - Effects of parenting interventions for at-risk parents with infants: a systematic review and meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29284713
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770968/pdf/bmjopen-2016-015707.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - The treatment effects of Mindfulness-Based Interventions (MBIs) with youth were synthesized from 76 studies involving 6121 participants. 

A total of 885 effect sizes were aggregated using meta-regression with robust variance estimation. Overall, MBIs were associated with small treatment effects in studies using pre-post (g = 0.305, SE = 0.039) and controlled designs (g = 0.322, SE = 0.040). Treatment effects were measured after a follow-up period in 24 studies (n = 1963). 

Results demonstrated that treatment effects were larger at follow-up than post-treatment in pre-post (g = 0.462, SE = 0.1 1 8) and controlled designs (g = 0.402, SE = 0.081). Moderator analyses indicated that intervention setting and intervention dosage were not meaningfully related to outcomes after controlling for study design quality. With that said, the between-study heterogeneity in the intercept-only models was consistently small, thus limiting the amount of variance for the moderators to explain. 

A series of exploratory analyses were used to investigate the differential effectiveness of MBIs across four therapeutic process domains and seven therapeutic outcome domains. Small, positive results were generally observed across the process and outcome domains. 

Notably, MBIs were associated with moderate effects on the process variable of mindfulness in controlled studies (n = 1108, g = 0.510). Limitations and directions for future research and practice are discussed. 

(C) 2017 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.
AN  - WOS:000405061800006
AU  - Klingbeil,
AU  - D.
AU  - A.
AU  - Renshaw,
AU  - T.
AU  - L.
AU  - Willenbrink,
AU  - J.
AU  - B.
AU  - Copek,
AU  - R.
AU  - A.
AU  - Chan,
AU  - K.
AU  - T.
AU  - Haddock,
AU  - A.
AU  - Yassine,
AU  - J.
AU  - Clifton,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jsp.2017.03.006
L1  - internal-pdf://1144013238/Klingbeil-2017-Mindfulness-based interventions.pdf
PY  - 2017
SP  - 77-103
TI  - Mindfulness-based interventions with youth: A comprehensive meta-analysis of group-design studies
UR  - &lt;Go to ISI&gt;://WOS:000405061800006
VL  - 63
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis examined the efficacy of adolescent cognitive-behavioral sleep interventions. Searches of PubMed, PsycINFO, CENTRAL, EMBASE, and MEDLINE were performed from inception to May 1, 2016, supplemented with manual screening. 

Nine trials were selected (n = 357, mean age = 14.97 years; female = 61.74%). Main outcomes were subjective (sleep diary/questionnaire) and objective (actigraphy) total sleep time (TST), sleep onset latency (SOL), sleep efficiency (SE), and wake after sleep onset (WASO). 

There were a small number of randomized controlled trials (RCTs; n = 4) and a high risk of bias across the RCTs; therefore, within sleep condition meta-analyses were examined (n = 221). At post-intervention, subjective TST improved by 29.47 min (95% CI 17.18, 41.75), SOL by 21.44 min (95% CI -30.78, -12.11), SE by 5.34% (95% CI 2.64, 8.04), and WASO by a medium effect size [d = 0.59 (95% CI 0.36, 0.82)]. 

Objective SOL improved by 16.15 min (95% CI -26.13, -6.17) and SE by 2.82% (95% CI 0.58, 5.07). Global sleep quality, daytime sleepiness, depression, and anxiety also improved. Gains were generally maintained over time. 

Preliminary evidence suggests that adolescent cognitive-behavioral sleep interventions are effective, but further high-quality RCTs are needed. 
Suggestions for further research are provided.
AN  - 28331991
AU  - Blake,
AU  - M.
AU  - J.
AU  - Sheeber,
AU  - L.
AU  - B.
AU  - Youssef,
AU  - G.
AU  - J.
AU  - Raniti,
AU  - M.
AU  - B.
AU  - Allen,
AU  - N.
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-017-0234-5
L1  - internal-pdf://1288666541/Blake-2017-Systematic Review and Meta-analysis.pdf
PY  - 2017
SP  - 22
TI  - Systematic Review and Meta-analysis of Adolescent Cognitive-Behavioral Sleep Interventions
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28331991
VL  - 22
ER  -
TY  - JOUR
AB  - **Background: **
Physical activity is associated with many physical and mental health benefits, however many children do not meet the national physical activity guidelines. While schools provide an ideal setting to promote children&#039;s physical activity, adding physical activity to the school day can be difficult given time constraints often imposed by competing key learning areas. Classroom-based physical activity may provide an opportunity to increase school-based physical activity while concurrently improving academic-related outcomes. The primary aim of this systematic review and meta-analysis was to evaluate the impact of classroom-based physical activity interventions on academic-related outcomes. A secondary aim was to evaluate the impact of these lessons on physical activity levels over the study duration. 

**Methods: **
A systematic search of electronic databases (PubMed, ERIC, SPORTDiscus, PsycINFO) was performed in January 2016and updated in January 2017. Studies that investigated the association between classroom-based physical activity interventions and academic-related outcomes in primary (elementary) school-aged children were included. Meta-analyses were conducted in Review Manager, with effect sizes calculated separately for each outcome assessed. 

**Results: **
Thirty-nine articles met the inclusion criteria for the review, and 16 provided sufficient data and appropriate design for inclusion in the meta-analyses. Studies investigated a range of academic-related outcomes including classroom behaviour (e.g. on-task behaviour), cognitive functions (e.g. executive function), and academic achievement (e.g. standardised test scores). Results of the meta-analyses showed classroom-based physical activity had a positive effect on improving on-task and reducing off-task classroom behaviour (standardised mean difference=0.60 (95% CI: 0.20,1.00)), and led to improvements in academic achievement when a progress monitoring tool was used (standardised mean difference=1.03 (95% CI: 0.22,1.84)). However, no effect was found for cognitive functions (standardised mean difference=0.33 (95% CI: -0.11,0.77)) or physical activity (standardised mean difference=0.40 (95% CI: -1.15,0.95)). 

**Conclusions: **
Results suggest classroom-based physical activity may have a positive impact on academic-related outcomes. However, it is not possible to draw definitive conclusions due to the level of heterogeneity in intervention components and academic-related outcomes assessed. Future studies should consider the intervention period when selecting academic-related outcome measures, and use an objective measure of physical activity to determine intervention fidelity and effects on overall physical activity levels. 

Copyright &copy; 2017 The Author(s).
AN  - 617962281
AU  - Watson,
AU  - A.
AU  - Timperio,
AU  - A.
AU  - Brown,
AU  - H.
AU  - Best,
AU  - K.
AU  - Hesketh,
AU  - K.
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s12966-017-0569-9
L1  - internal-pdf://1797253466/Watson-2017-Effect of classroom-based physical.pdf
PY  - 2017
T2  - International Journal of Behavioral Nutrition and Physical Activity
TI  - Effect of classroom-based physical activity interventions on academic and physical activity outcomes: A systematic review and meta-analysis
UR  - http://www.ijbnpa.org/home/
UR  - https://ijbnpa.biomedcentral.com/track/pdf/10.1186/s12966-017-0569-9
VL  - 14 (1) (no pagination)
ER  -
TY  - JOUR
AB  - Positive youth development is thought to be essential to the prevention of adolescent risk behavior and the promotion of thriving. This meta-analysis examined the effects of positive youth development interventions in promoting positive outcomes and reducing risk behavior. 

Ten databases and grey literature were scanned using a predefined search strategy. We included studies that focused on young people aged 10-19 years, implemented a positive youth development intervention, were outside school hours, and utilized a randomized controlled design. 

Twenty-four studies, involving 23,258 participants, met the inclusion criteria and were included in the analysis. The impact of the interventions on outcomes including behavioral problems, sexual risk behavior, academic achievement, prosocial behavior and psychological adjustment were assessed. 

Positive youth development interventions had a small but significant effect on academic achievement and psychological adjustment. No significant effects were found for sexual risk behaviors, problem behavior or positive social behaviors. Intervention effects were independent of program characteristics and participant age. Low-risk young people derived more benefit from positive youth development interventions than high-risk youth. The studies examined had several methodological flaws, which weakened the ability to draw conclusions. 

Substantial progress has been made in the theoretical understanding of youth development in the past two decades. This progress needs to be matched in the intervention literature, through the use of high-quality evaluation research of positive youth development programs.
AD  - Ciocanel, Oana. Sexual Health and Blood Borne Virus Team, Kings Cross Hospital, NHS Tayside, Clepington Road, Dundee, DD3 8EA, UK. Power, Kevin. School of Natural Sciences, University of Stirling, Stirling, UK. Power, Kevin. Area Psychological Therapies Service, NHS Tayside, 7 Dudhope Terrace, Dundee, DD3 6HG, UK. Eriksen, Ann. Sexual Health and Blood Borne Virus Team, Kings Cross Hospital, NHS Tayside, Clepington Road, Dundee, DD3 8EA, UK. Gillings, Kirsty. Psychology Department, Stratheden Hospital, NHS Fife, Cupar, Fife, KY15 5RR, Scotland. kirsty.gillings@nhs.net.
AN  - 27518860
AU  - Ciocanel,
AU  - O.
AU  - Power,
AU  - K.
AU  - Eriksen,
AU  - A.
AU  - Gillings,
AU  - K.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10964-016-0555-6
DP  - Ovid Technologies
J2  - J Youth Adolesc
L1  - internal-pdf://3042094889/Ciocanel-2017-Effectiveness of Positive Youth.pdf
LA  - English
N1  - Ciocanel, Oana Power, Kevin Eriksen, Ann Gillings, Kirsty 10.1007/s10964-016-0555-6
PY  - 2017
SP  - 483-504
T2  - Journal of Youth &amp; Adolescence
TI  - Effectiveness of Positive Youth Development Interventions: A Meta-Analysis of Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27518860http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27518860&amp;id=doi:10.1007%2Fs10964-016-0555-6&amp;issn=0047-2891&amp;isbn=&amp;volume=46&amp;issue=3&amp;spage=483&amp;pages=483-504&amp;date=2017&amp;title=Journal+of+Youth+%26+Adolescence&amp;atitle=Effectiveness+of+Positive+Youth+Development+Interventions%3A+A+Meta-Analysis+of+Randomized+Controlled+Trials.&amp;aulast=Ciocanel&amp;pid=%3Cauthor%3ECiocanel+O%3C%2Fauthor%3E%3CAN%3E27518860%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s10964-016-0555-6
UR  - http://download.springer.com/static/pdf/695/art%253A10.1007%252Fs10964-016-0555-6.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10964-016-0555-6&amp;token2=exp=1489074109~acl=%2Fstatic%2Fpdf%2F695%2Fart%25253A10.1007%25252Fs10964-016-0555-6.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10964-016-0555-6*~hmac=484e05dec316c848d352e41882f37f935c163176587d2e578c7c783d723b7895
VL  - 46
ER  -
TY  - JOUR
AB  - Disorganized attachment is associated with a host of negative developmental outcomes, leading to a growing interest in preventative interventions targeting the attachment relationship in infancy. The objective of this meta-analysis was to assess the effectiveness of interventions that aimed to prevent or reduce rates of disorganization among children at risk. 

We performed a literature search using PsycINFO, MEDLINE, and ProQuest databases for studies published between January 1989 and August 2016. All 16 studies (N = 1,360) included a control condition and reported postintervention rates of organized and disorganized attachments assessed by the Strange Situation Procedure. Results showed that, overall, interventions were effective in increasing rates of organized attachment compared to control conditions (d = 0.35, 95% CI [0.10-0.61]). 

Moderator analyses demonstrated that interventions were more effective (a) in more recently published studies than in older studies, (b) for maltreated samples than nonmaltreated samples, and (c) as children increased in age. These results have important implications for future development, tailoring, and implementation of attachment-based intervention programs.
AN  - 28397637
AU  - Facompre,
AU  - C.
AU  - R.
AU  - Bernard,
AU  - K.
AU  - Waters,
AU  - T.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1017/S0954579417000426
L1  - internal-pdf://0346722932/Facompre-2017-Effectiveness of interventions i.pdf
PY  - 2017
SP  - 1-11
TI  - Effectiveness of interventions in preventing disorganized attachment: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28397637
ER  -
TY  - JOUR
AB  - **Background**
Excessive alcohol use contributes significantly to physical and psychological illness, injury and death, and a wide array of social harm in all age groups. A proven strategy for reducing excessive alcohol consumption levels is to offer a brief conversation‐based intervention in primary care settings, but more recent technological innovations have enabled people to interact directly via computer, mobile device or smartphone with digital interventions designed to address problem alcohol consumption.

**Objectives**
To assess the effectiveness and cost‐effectiveness of digital interventions for reducing hazardous and harmful alcohol consumption, alcohol‐related problems, or both, in people living in the community, specifically: (i) Are digital interventions more effective and cost‐effective than no intervention (or minimal input) controls? (ii) Are digital interventions at least equally effective as face‐to‐face brief alcohol interventions? (iii) What are the effective component behaviour change techniques (BCTs) of such interventions and their mechanisms of action? (iv) What theories or models have been used in the development and/or evaluation of the intervention? Secondary objectives were (i) to assess whether outcomes differ between trials where the digital intervention targets participants attending health, social care, education or other community‐based settings and those where it is offered remotely via the internet or mobile phone platforms; (ii) to specify interventions according to their mode of delivery (e.g. functionality features) and assess the impact of mode of delivery on outcomes.

**Search methods**
We searched CENTRAL, MEDLINE, PsycINFO, CINAHL, ERIC, HTA and Web of Knowledge databases; ClinicalTrials.com and WHO ICTRP trials registers and relevant websites to April 2017. We also checked the reference lists of included trials and relevant systematic reviews.

**Selection criteria**
We included randomised controlled trials (RCTs) that evaluated the effectiveness of digital interventions compared with no intervention or with face‐to‐face interventions for reducing hazardous or harmful alcohol consumption in people living in the community and reported a measure of alcohol consumption.

**Data collection and analysis**
We used standard methodological procedures expected by The Cochrane Collaboration.

**Main results**
We included 57 studies which randomised a total of 34,390 participants. The main sources of bias were from attrition and participant blinding (36% and 21% of studies respectively, high risk of bias). Forty one studies (42 comparisons, 19,241 participants) provided data for the primary meta‐analysis, which demonstrated that participants using a digital intervention drank approximately 23 g alcohol weekly (95% CI 15 to 30) (about 3 UK units) less than participants who received no or minimal interventions at end of follow up (moderate‐quality evidence).

Fifteen studies (16 comparisons, 10,862 participants) demonstrated that participants who engaged with digital interventions had less than one drinking day per month fewer than no intervention controls (moderate‐quality evidence), 15 studies (3587 participants) showed about one binge drinking session less per month in the intervention group compared to no intervention controls (moderate‐quality evidence), and in 15 studies (9791 participants) intervention participants drank one unit per occasion less than no intervention control participants (moderate‐quality evidence).

Only five small studies (390 participants) compared digital and face‐to‐face interventions. There was no difference in alcohol consumption at end of follow up (MD 0.52 g/week, 95% CI ‐24.59 to 25.63; low‐quality evidence). Thus, digital alcohol interventions produced broadly similar outcomes in these studies. No studies reported whether any adverse effects resulted from the interventions.

A median of nine BCTs were used in experimental arms (range = 1 to 22). &#039;B&#039; is an estimate of effect (MD in quantity of drinking, expressed in g/week) per unit increase in the BCT, and is a way to report whether individual BCTs are linked to the effect of the intervention. The BCTs of goal setting (B ‐43.94, 95% CI ‐78.59 to ‐9.30), problem solving (B ‐48.03, 95% CI ‐77.79 to ‐18.27), information about antecedents (B ‐74.20, 95% CI ‐117.72 to ‐30.68), behaviour substitution (B ‐123.71, 95% CI ‐184.63 to ‐62.80) and credible source (B ‐39.89, 95% CI ‐72.66 to ‐7.11) were significantly associated with reduced alcohol consumption in unadjusted models. In a multivariable model that included BCTs with B &gt; 23 in the unadjusted model, the BCTs of behaviour substitution (B ‐95.12, 95% CI ‐162.90 to ‐27.34), problem solving (B ‐45.92, 95% CI ‐90.97 to ‐0.87), and credible source (B ‐32.09, 95% CI ‐60.64 to ‐3.55) were associated with reduced alcohol consumption.

The most frequently mentioned theories or models in the included studies were Motivational Interviewing Theory (7/20), Transtheoretical Model (6/20) and Social Norms Theory (6/20). Over half of the interventions (n = 21, 51%) made no mention of theory. Only two studies used theory to select participants or tailor the intervention. There was no evidence of an association between reporting theory use and intervention effectiveness.

**Authors&#039; conclusions**
There is moderate‐quality evidence that digital interventions may lower alcohol consumption, with an average reduction of up to three (UK) standard drinks per week compared to control participants. Substantial heterogeneity and risk of performance and publication bias may mean the reduction was lower. Low‐quality evidence from fewer studies suggested there may be little or no difference in impact on alcohol consumption between digital and face‐to‐face interventions.

The BCTs of behaviour substitution, problem solving and credible source were associated with the effectiveness of digital interventions to reduce alcohol consumption and warrant further investigation in an experimental context.

Reporting of theory use was very limited and often unclear when present. Over half of the interventions made no reference to any theories. Limited reporting of theory use was unrelated to heterogeneity in intervention effectiveness.
AU  - Kaner,
AU  - E.
AU  - Beyer,
AU  - F.
AU  - Garnett,
AU  - C.
AU  - Crane,
AU  - D.
AU  - Brown,
AU  - J.
AU  - Muirhead,
AU  - C.
AU  - Redmore,
AU  - J.
AU  - O&#039;Donnell,
AU  - A.
AU  - Newham,
AU  - J.
AU  - de
AU  - Vocht,
AU  - F.
AU  - Hickman,
AU  - M.
AU  - Brown,
AU  - H.
AU  - Maniatopoulos,
AU  - G.
AU  - Michie,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD011479.pub2
PY  - 2017
T2  - Cochrane Database of Systematic Reviews
TI  - Personalised digital interventions for reducing hazardous and harmful alcohol consumption in community-dwelling populations
VL  - 9
ER  -
TY  - JOUR
AB  - **Background**
Due to educational policy initiatives over the last two decades, school districts across the United States have placed more emphasis on improving academic standards and accountability. Indeed, children are spending between 20 to 25 hours per year on meeting federal, state and local school-district testing requirements (Hart et al., 2015). This increased emphasis on academic standards and high stakes testing has, at least in part, been blamed for the increasing levels of stress and anxiety children are experiencing (APA, 2009; Merkangas et al., 2010; Pope, 2010). In addition to changes in education policy requiring an increased emphasis on academic standards and accountability, schools are increasingly expected to attend to the social, emotional, and behavioral needs and problems of students. Given that as many as 13% to 20% children in the U.S. are experiencing one or more mental disorders (Center for Disease Control and Prevention, 2013), schools are increasingly challenged to respond to the growing emotional and behavioral needs of their students. Moreover, socioemotional development and competencies have been linked to learning and academic achievement, and have thus become a target for school-based interventions as a means of improving learning and academic achievement (Durlak, Weisberg, Dymnicki, Taylor, &amp; Schhellinger, 2011; Eisenberg, Spinrade, &amp; Eggum, 2010; Zins &amp; Elias, 2006).

One approach to supporting improvements in socioemotional development and competencies that has received growing interest for use in schools is mindfulness-based interventions (MBIs). Mindfulness is defined as &ldquo;paying attention in a particular way: on purpose, in the present moment, nonjudgementally&rdquo; (Zabat-Zinn, 1994, p. 4). Research suggests positive effects of MBIs for adults with chronic conditions, mental health diagnoses, psychiatric disorders, and stress (Chiesa, Calati, &amp; Serretti, 2011; deVibe et al., 2012; Cramer, Haller, Lauche, &amp; Dobos, 2012; Vollestad, B. Nielsen, &amp; H. Nielsen, 2012. Moreover, studies suggest that mindfulness based practices may improve performance on a variety of socioemotional outcomes, including self-regulation, stress, and mood disturbance (Cheisa &amp; Serretti, 2009; Regehr, Glancy, &amp; Pitts, 2013). There has been increasing interest in MBIs with children and adolescents, and schools are often seen as a convenient setting to implement MBIs with children and youth. Some of the more popular MBIs used in schools are Mindfulness Based Stress Reduction (MBSR; Kabat-Zinn, 1979; Bootzin &amp; Stevens, 2005), Mindfulness Based Cognitive Therapy for Children (MBCT-C; Segal, Williams, &amp; Teasdale, 2002; Semple, Reid, &amp; Miller, 2005), Meditation of the Soles of the Feet (SoF; Singh et al., 2007), and Learning to Breath (LTB; Broderick &amp; Metz, 2009). Despite the dramatic increase in the use of MBIs in schools to affect socioemotional and academic outcomes, little effort has been invested to systematically examine the body of evidence using rigorous methods, particularly for behavioral and academic outcomes of MBIs implemented in school settings.

This review contributes to the literature by including the most recent research on MBIs in school settings, including outcomes that have not been examined in prior reviews of school-based mindfulness interventions, including behavioral and academic outcomes, and employing stringent criteria for search, selection, coding, and analysis as specified in the Campbell Collaboration policies and guidelines to inform educational policy and practice and identify gaps in the current evidence base to guide future research in this growing area of practice and research.

**Objectives**
The purpose of this review is to examine and synthesize evidence of mindfulness-based interventions implemented in school settings with primary and secondary school students on achievement, behavior and socioemotional outcomes to inform education practice and policy. Specifically, the primary aim of this review is designed to answer the following research question: 1. What are the effects of mindfulness-based interventions on cognition, academic achievement, behavior and socioemotional outcomes? Moreover, within the context of this review, we aim to describe:

The types of mindfulness-based interventions being evaluated in school settings.
The state and quality of evidence of intervention outcomes studies of mindfulness-based interventions in school settings?
Search methods
We attempted to identify and retrieve both published and unpublished studies through a comprehensive search that included multiple electronic databases, research registers, grey literature sources, and reference lists of reviews and relevant studies. We searched 13 electronic databases, research registers, relevant clearinghouse, government and research center websites, conference abstracts/proceedings, reference lists of prior reviews and included studies, and contact with experts and researchers in the area of school-based mindfulness interventions.

**Selection criteria**
Studies were included in this review if they met the following criteria:

**Types of studies:** Randomized controlled trial (RCT), quasi-experimental design (QED), single-group pre-post test design (SGPP) or single subject design (SSD). We only included RCT and QED studies in the meta-analyses.

**Participants:** Pre-school, primary and secondary school students

**Interventions: **Interventions of interest include those that are a) conducted in a school setting (during the school day or in a school-based after school program) and b) use a mindfulness component/strategy. Mindfulness is broadly defined as &ldquo;self-regulation of attention to the conscious awareness of one&#039;s immediate experiences while adopting an attitude of curiosity, openness, and acceptance&rdquo; (Bishop et al., 2004, p. 174).

**Outcomes:** Studies must have reported at least one of the following outcomes:

1. Cognition (e.g., executive function, memory, cognition, attention)

2. Academic performance (e.g., standardized achievement tests, measures of content mastery, reading, grades)

3. Behavior (e.g., disciplinary referrals, aggression and other externalizing behaviors, time on task, compliance, attendance)

4. Socioemotional (e.g., anxiety, stress, engagement, social skills, self-esteem, emotion regulation, grit, internalizing behaviors)

5. Physiological (e.g., cortisol, heart rate, brain activity)

**Other criteria:** Studies must have reported post-test data, interventions must have been conducted in a primary or secondary school setting, and must have been conducted or published between 1990 and 2015. The search was not restricted by geography, language, publication status or other study characteristics.


**Data collection and analysis**
Titles and abstracts of the studies found through the search procedures were screened for relevance by two reviewers for most electronic databases, with the exception of the Australian Education Index, the British Education Index, and CBCA Education which were reviewed by one author. Documents that were not obviously ineligible or irrelevant based on the title and abstract review were retrieved in full text for final eligibility screening. Two reviewers independently reviewed each full text report using a screening form to determine final inclusion. Any discrepancies between the reviewers were discussed and resolved through consensus. For all studies that passed the eligibility screening process described above, two reviewers independently coded each eligible study using a structured data extraction form. Following independent coding of studies, coders then compared coding and identified and discussed discrepancies, which were resolved through consensus. If consensus could not be reached between the two coders, a third member of the review team was consulted to resolve the discrepancy. We conducted descriptive analyses on variables of interest from all included studies to provide information regarding participant, setting, intervention characteristics for all studies that met eligibility criteria. For those that met criteria for inclusion in the meta-analysis, we estimated effect sizes for each included RCT and QED study when enough data was reported in the study or provided by study authors. For RCT and QED studies, we calculated the magnitude of effect using the standardized mean difference effect size with Hedges&rsquo; g correction for continuous outcomes and odds ratios for outcomes presented as dichotomous variables.

Following the estimation of individual study level effects, we conducted separate meta-analyses using Comprehensive Meta-Analysis, version 3.0 (CMA; Borenstein, Hedges, Higgins, &amp; Rothstein, 2014) for the following outcome domains of interest: cognitive, academic, behavioral and socioemotional outcomes. To synthesize effects across studies, a weighted mean effect was calculated by weighting each study level effect size by the inverse of its variance. Random effects statistical models were used throughout. RCT and QED studies were pooled to allow for greater statistical power in all meta-analyses (heterogeneity between RCT and QED studies was not statistically significant in any of the meta-analyses). Following the estimation of summary effects, we conducted a test of homogeneity (Q-test) to compare the observed variance to what would be expected from sampling error. The I2 statistic was used to describe the percentage of total variation across studies due to the heterogeneity rather than chance. We also constructed a forest plot displaying study-level mean effect sizes and 95% confidence intervals for the included studies to provide opportunity for visual analysis of the precision of the estimated effect sizes, detection of studies with extreme effects, and information regarding heterogeneity of studies. Publication bias was assessed using funnel plots. When there was significant heterogeneity across studies, we conducted moderator analyses to examine the following variables: study type (RCT, QED), provider (classroom teacher, trained instructor), researcher involvement (yes/no), homework (yes/no), manualized program (yes/no), and number of weeks (# of weeks of the intervention).

**Results**
Of the 61 studies that met criteria for inclusion in this review, 25 were RCT studies, 19 were QED studies, 9 were SGPP studies and 8 were SSD studies. Of the 44 RCT and QED studies, 35 provided enough data to calculate an effect size and were included in one or more of the meta-analyses, depending on which outcomes of interest were reported in the studies. Of the 44 RCT and QED studies, seven were unpublished reports, with the remaining being published studies in peer-reviewed journals. The interventions represent a wide range of mindfulness intervention types, but most interventions were at least partially manualized and of shorter duration. The interventions were delivered by primarily a classroom teacher (31%) or by a mindfulness-trained interventionist (60%) external to the school system.

Meta-analytic findings indicate small, yet statistically significant effects on cognitive outcomes (k = 10; g = 0.25 (95% CI [0.06, 0.43], p = .01) and socioemotional outcomes (k = 28; g = 0.22 (95% CI [0.14, 0.30], p &lt; .001), and small and non-significant effects on academic outcomes (k = 5; g = 0.27 (95% CI [-0.04, 0.57], p = .08.) and behavioral outcomes (k = 13; g = 0.14 (95% CI [-0.02, 0.30], p = .08). Heterogeneity was small and not statistically significant in all meta-analyses with the exception of behavioral outcomes (I2 = 48%; T2 = .034; Q = 22.96, p = .03). Six studies measured physiological factors, with three of those studies from the same author team. Due to the nature of these measures, the time dependency of some of these measures (cannot compare AM cortisol to PM cortisol for example), and that so few studies measured these outcomes, quantitatively synthesizing these outcomes across these studies was not warranted.

Overall, there was a moderate to high risk of bias across the 35 studies included in the meta-analyses, with variation in high risk areas across studies. Twenty-one studies (60%) were rated low risk and 14 studies (40%) were rated high risk of bias for random sequence generation. Only one study reported that participants and study and school staff were blinded to program allocation (Sibinga et al., 2013), although they did not specify how they blinded study and school staff to condition. The remaining studies were rated as high risk (86%) or unclear risk (11%). Most of the studies in this review were rated as low risk of attrition bias (74%). For the studies included in the meta-analyses, most studies were assessed as unclear risk for reporting bias as we could not find any protocols of studies with which to compare planned to actual reported outcomes. It must be noted, however, that several studies reported to use, and then only reported data for, subscales of measures rather than reporting the full measure score or all subscale scores. Thus, it is unclear whether the a priori intentions of these authors were to only use certain subscales or if the participants did complete the full measure and the study authors only described the use of and reported data for the subscale only. We also coded for additional factors related to potential bias in this corpus of studies: researcher allegiance bias, funding source bias, and confounding factors. Of the 35 studies included in the meta-analysis, we were able to clearly identify an author role in the development and/or delivery of the intervention in 18 (51%) of the studies. The funding source was often not reported, or the studies were not funded. In four of the studies (11%), the authors identified a funding source that was also an entity involved in the development or the delivery of the intervention. We also examined whether there were confounding factors with either the treatment or comparison groups. Thirteen studies (37%) were assessed as having a confound at the level of the instructor (n = 7; only one instructor in treatment, control or both conditions) or at the school/classroom level (n = 6; one classroom or school in the treatment, control or both conditions). A larger mean effect was observed for studies in which a confound was present, thus likely upwardly biasing results; however, we conducted sensitivity analysis and found that the difference in magnitude of effect between studies with and without confounds was not statistically significant.

**Authors&rsquo; conclusions**
Results indicate mixed results of school-based mindfulness interventions across the outcomes of interest in this review, with finding favorable impacts of mindfulness interventions on those processes that are likely more directly targeted by mindfulness interventions, namely cognitive and socioemotional outcomes. We found a lack of support at posttest to indicate that those positive effects on cognitive and socioemotional outcomes then translate into favorable outcomes for academic and behavioral outcomes as is hypothesized. The lack of heterogeneity for all outcomes with the exception of the behavioral outcomes indicate that the interventions in this review, although quite diverse in their characteristics, produced similar results across studies on cognitive, socioemotional and academic outcomes. These findings provide some support for the use of school-based mindfulness interventions for some outcomes, but do not provide overwhelming support of MBIs as being the panacea as some have advocated. The quality of the evidence varied, with some important risks of bias present across a large proportion of studies which threatens the internal validity of the included studies and is cause for caution in interpreting the results of this review.

Overall, the evidence from this review urges caution in the enthusiasm for, and widespread adoption of, school-based mindfulness interventions for children and youth. While the evidence points to positive effects on socioemotional and cognitive outcomes, there is a lack of evidence of effects on academic and behavioral outcomes. Despite the empirical support of mindfulness-based interventions for adults, children and adolescents may not benefit from mindfulness-based interventions similarly to adults. Children and adolescents may not be developmentally ready for the complex cognitive tasks, focus and level of awareness that mindfulness-based interventions require. Moreover, we know little about the costs and adverse effects of school-based mindfulness interventions&mdash;the costs of implementing these programs may not be justified, and there are some indications that mindfulness-based interventions may have some adverse effects on children and youth; however, these have not been adequately examined. If schools do want to implement mindfulness-based interventions, we urge schools to evaluate the practice in a rigorous way and monitor outcomes and costs.
AU  - Maynard,
AU  - R.
AU  - Solis,
AU  - M.
AU  - Miller,
AU  - V.
AU  - Brendel,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.campbellcollaboration.org/library/mindfulness-based-interventions-primary-and-secondary-school-students.html
PY  - 2017
T2  - Campbell Systematic Reviews
TI  - Mindfulness-based interventions for improving cognition, academic achievement, behavior and socio-emotional functioning of primary and secondary students
VL  - 13
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Emerging evidence suggests that cognitive bias modification of interpretations (CBM-I) is effective in altering interpretation biases and reducing anxiety in adults. Less is known about the impact of CBM-I in young people, but some recent findings, including a meta-analysis of combined cognitive bias modification of interpretation and attention techniques, have cast doubt on its clinical utility. Given the current debate, this meta-analysis sought to establish the independent effects of CBM-I on interpretations biases and anxiety in youth. 

**METHODS: **
Studies were identified through a systematic literature search of PsycINFO, Ovid MEDLINE, PsycARTICLES, Web of Science and EMBASE between January 1992 and March 2017. Eligible studies aimed to target interpretation biases; did not combine CBM-I with another intervention; included a control condition; randomly allocated participants to conditions; assessed interpretation bias and/or anxiety as an outcome; included individuals up to age 18; and did not present previously reported data. Reference lists of included articles were checked for further eligible studies, and authors were contacted for unpublished data. 

**RESULTS:**
We identified 26 studies meeting eligibility criteria that included in the meta-analysis. CBM-I had moderate effects on negative and positive interpretations (g = -0.70 and g = -0.52, respectively) and a small but significant effect on anxiety assessed after training (g = -0.17) and after a stressor (g = -0.34). No significant moderators were identified. 

**CONCLUSIONS: **
In contrast to previous meta-analytic findings, our results indicate that CBM-I has potential but weak anxiolytic effects in youth. Our findings suggest that it may be premature to disregard the potential value of CBM-I research and further research in this field is warranted.
AN  - 29052837
AU  - Krebs,
AU  - G.
AU  - Pile,
AU  - V.
AU  - Grant,
AU  - S.
AU  - Degli
AU  - Esposti,
AU  - M.
AU  - Montgomery,
AU  - P.
AU  - Lau,
AU  - J.
AU  - Y.
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.12809
L1  - internal-pdf://0820333025/Krebs-2017-Research Review_ Cognitive bias mod.pdf
PY  - 2017
SP  - 20
TI  - Research Review: Cognitive bias modification of interpretations in youth and its effect on anxiety: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29052837
VL  - 20
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering om effektene av Zero, som er et universalforebyggende program mot mobbing, og som retter seg mot barn og unge i skolen. Artikkelen er en revisjon av en tidligere evaluering av Zero i Ungsinn (Martinussen &amp; Eng, 2010), og er omarbeidet i henhold til Ungsinns nye kriterier og prosedyrer for vurdering og klassifisering av tiltak (Martinussen m. fl., 2016). Hovedmålet med programmet er å redusere mobbing, forebygge at mobbing oppstår, samt øke trivsel på skolen og redusere angst for å bli mobbet. Programmet er ikke manualbasert, men bygger på prinsippet om nulltoleranse for mobbing, autoritative voksne, konsistens og kontinuitet. Dette innebærer at det ikke tillates at elever er ubehagelige mot hverandre, voksne skal utøve en kombinasjon av støtte og kontroll, og at antimobbearbeidet skal integreres i skolens totale virksomhet. Ansatte, elever og foreldre involveres slik at det forankres på skolen på alle nivåer. Skolene utarbeider egne handlingsplaner mot mobbing basert på prinsippene og ideene i Zero-programmet. De sentrale områdene det arbeides etter er avdekking, problemløsning, forebygging og kontinuitet. Elevrådet involveres også, og oppfordres til å jobbe systematisk med antimobbearbeid i og utenfor klasserommet. Programmet er utviklet av læringsmiljøsenteret i Stavanger, men implementeres for tiden ikke aktivt. Videre utvikling og tilrettelegging av programmet avhenger av myndighetenes prioriteringer.

METODE
Kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline, Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS, og SweMed, rapporter fra kunnskapssenteret, NREPP, NICE og Blueprint, samt informasjon gitt fra tiltakseier.

RESULTATER
Litteratursøket resulterte i &eacute;n effektstudie. Dette var en evaluering av programmet som ble gjennomført i 2003/2004 med til sammen 146 skoler og over 20000 elever. Denne studien benyttet seg av to kvasi-eksperimentelle design. Gjennom det ene designet ble elevene i skolene som deltok i Zero-programmet sammenlignet med elever som ikke deltok i programmet. Det andre designet var et pretest-posttest design hvor endring i mobbeatferd undersøkes over et år for alle elevene på skolene som deltar i Zero-programmet. Studien har enkelte metodiske begrensninger og svake funn, spesielt med tanke på sammenligningen mellom Zero-skoler og andre skoler.

KONKLUSJON
Zero er et godt beskrevet program, med gode rutiner for implementering og en sterk teoretisk forankring. Det er imidlertid behov for oppdatering av programmet, spesielt for å tilpasse dette den nye digitale hverdagen og nyere teori om mobbing. Det er også behov for effektstudier med bedre kvalitet for å kunne konkludere med om tiltaket er mer virksomt enn ordinær praksis.

Zero klassifiseres på evidensnivå 3: Tiltak med noe dokumentasjon på effekt.
AU  - Holen,
AU  - S.,
AU  - Martinussen,
AU  - M.,
AU  - Eng,
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - Tom verdi
PY  - 2017
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Zero (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/zero-2-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - **ISSUES: **
Alcohol and other drug use among adolescents is a serious concern, and effective prevention is critical. Research indicates that expanding school-based prevention programs to include parenting components could increase prevention outcomes. This paper aims to identify and describe existing combined student- and parent-based programs for the prevention of alcohol and other drug use to evaluate the efficacy of existing programs. 

**APPROACH: **
The PsycINFO, Medline, Central Register of Controlled trials and Cochrane databases were searched in April 2015 and additional articles were obtained from reference lists. Studies were included if they evaluated a combined universal intervention for students (aged 11-18 years old) and their parents designed to prevent alcohol and/or other drug use, and were delivered in a school-based setting. Risk of bias was assessed by two independent reviewers. Because of the heterogeneity of the included studies, it was not possible to conduct a meta-analysis and a qualitative description of the studies was provided. 

**KEY FINDINGS: **
From a total of 1654 screened papers, 22 research papers met inclusion criteria, which included 13 trials of 10 programs. Of these, nine programs demonstrated significant intervention effects in terms of delaying or reducing adolescent alcohol and/or other drug use in at least one trial. 

**CONCLUSION: **
This is the first review of combined student- and parent-based interventions to prevent and reduce alcohol and other drug use. Whilst existing combined student- and parent-based programs have shown promising results, key gaps in the literature have been identified and are discussed in the context of the development of future prevention programs. [Newton NC, Champion KE, Slade T, Chapman C, Stapinski L, Koning I, Tonks Z, Teesson M. A systematic review of combined student- and parent-based programs to prevent alcohol and other drug use among adolescents. Drug Alcohol Rev 2017;36:337-351].
AN  - 28334456
AU  - Newton,
AU  - N.
AU  - C.
AU  - Champion,
AU  - K.
AU  - E.
AU  - Slade,
AU  - T.
AU  - Chapman,
AU  - C.
AU  - Stapinski,
AU  - L.
AU  - Koning,
AU  - I.
AU  - Tonks,
AU  - Z.
AU  - Teesson,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/dar.12497
L1  - internal-pdf://1486744070/Newton-2017-A systematic review of combined st.pdf
PY  - 2017
SP  - 337-351
T2  - Drug &amp; Alcohol Review
TI  - A systematic review of combined student- and parent-based programs to prevent alcohol and other drug use among adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=28334456
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1111/dar.12497
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/dar.12497
VL  - 36
ER  -
TY  - JOUR
AB  - **CONTEXT: **
Parent-child interaction therapy (PCIT) is effective at reducing children&#039;s externalizing behavior. However, modifications are often made to PCIT, and it is not known whether these impact effectiveness. 

**OBJECTIVE: **
To systematically review and meta-analyze the effects of PCIT on child externalizing behaviors, considering modifications, study design, and bias. 

**DATA SOURCES: **
We searched PubMed, PsycINFO, Education Resources Information Center, Sociological Abstracts, and A+ Education. 

**STUDY SELECTION: **
We selected randomized controlled or quasi-experimental trials. 

**DATA EXTRACTION: **
We analyzed child externalizing and internalizing behaviors, parent stress, parent-child interactions, PCIT format, and study design and/or characteristics. 

**RESULTS: **
We included 23 studies (1144 participants). PCIT was superior to control for reducing child externalizing (standardized mean difference [SMD]: -0.87, 95% confidence interval [CI]:-1.17 to -0.58). PCIT studies that required skill mastery had significantly greater reductions in externalizing behavior than those that did not (Mastery: SMD: -1.09, 95% CI: -1.44 to -0.73; Nonmastery: SMD: -0.51,95% CI: -0.85 to -0.17, P = .02). Compared with controls, PCIT significantly reduced parent-related stress (mean difference [MD]: -6.98, 95% CI: -11.69 to -2.27) and child-related stress (MD: -9.87, 95% CI: -13.64 to -6.09). Children in PCIT were observed to be more compliant to parent requests (SMD: 0.89, 95% CI: 0.50 to 1.28) compared with controls. PCIT effectiveness did not differ depending on session length, location (academic versus community settings), or child problems (disruptive behaviors only compared with disruptive behavior and other problems). 

**LIMITATIONS: **
Results for parent-child observations were inconsistently reported, reducing the ability to pool important data. 

**CONCLUSIONS: **
PCIT has robust positive outcomes across multiple parent-reported and observed parent-child interaction measures, and modifications may not be required even when implemented in diverse populations.
AN  - 28860132
AU  - Thomas,
AU  - R.
AU  - Abell,
AU  - B.
AU  - Webb,
AU  - H.
AU  - J.
AU  - Avdagic,
AU  - E.
AU  - Zimmer-Gembeck,
AU  - M.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1542/peds.2017-0352
L1  - internal-pdf://4230797137/Thomas-2017-Parent-Child Interaction Therapy_.pdf
PY  - 2017
TI  - Parent-Child Interaction Therapy: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=28860132
VL  - 140
ER  -
TY  - JOUR
AB  - **Objective: **
A large proportion of paediatric patients with attention-deficit/hyperactivity disorder (ADHD) have associated sleep problems which not only affect the child&#039;s wellbeing but also impact family functioning. Management of sleep problems is consequently an important aspect of overall ADHD management in paediatric patients. Although some drugs are being used off-label for the management of paediatric insomnia, there is scant clinical evidence supporting their use. Our aim was to identify and assess the quality of published studies reporting the safety, tolerability and efficacy of drugs used for treating behavioural insomnia in children with ADHD. 

**Methods: **
After an initial screen to determine which drugs were most commonly used, we conducted a systematic review of English-language publications from searches of PubMed, EMBASE, PsycINFO and two trial register databases to February 2017, using keywords &#039;clonidine&#039;, &#039;melatonin&#039;, &#039;zolpidem&#039;, &#039;eszopiclone&#039;, &#039;L-theanine&#039;, &#039;guanfacine&#039;, &#039;ADHD&#039;, &#039;sleep disorder&#039; and &#039;children&#039;. For quality assessment of included studies, we used the CONSORT checklist for randomised control trials (RCTs) and the Downs and Black checklist for non-RCTs. 

**Results: **
Twelve studies were included. Two case series for clonidine, two RCTs and four observational studies for melatonin and one RCT each for zolpidem, eszopiclone, L-theanine and guanfacine. Of the 12 included studies, only one on eszopiclone scored excellent for quality. The quality of the rest of the studies varied from moderate to low. For clonidine, melatonin and L-theanine, improvements in sleep-onset latency and total sleep duration were reported; however, zolpidem, eszopiclone and guanfacine failed to show any improvement when compared with placebo. Clonidine, melatonin, L-theanine, eszopiclone and guanfacine were well tolerated with mild to moderate adverse events; zolpidem was associated with neuropsychiatric adverse effects.

**Conclusion:**
There is generally poor evidence for prescribing drugs for behavioural insomnia in children with ADHD. Further controlled studies are warranted. 

Copyright &copy; 2017, Springer International Publishing Switzerland.
AN  - 615271266
AU  - Anand,
AU  - S.
AU  - Tong,
AU  - H.
AU  - Besag,
AU  - F.
AU  - M.
AU  - C.
AU  - Chan,
AU  - E.
AU  - W.
AU  - Cortese,
AU  - S.
AU  - Wong,
AU  - I.
AU  - C.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s40272-017-0224-6
L1  - internal-pdf://4242069375/Anand-2017-Safety, Tolerability and Efficacy o.pdf
PY  - 2017
SP  - 235-250
TI  - Safety, Tolerability and Efficacy of Drugs for Treating Behavioural Insomnia in Children with Attention-Deficit/Hyperactivity Disorder: A Systematic Review with Methodological Quality Assessment
UR  - http://rd.springer.com/journal/40272
VL  - 19
ER  -
TY  - JOUR
AB  - The purpose of this review is to report on the effectiveness of peer-mediated interventions on academic outcomes for students with emotional and behavioral disorders (EBD). CEC standards for evidence-based practices were used for determination of methodologically sound studies. 

Twenty-four studies involving 288 participants met inclusionary criteria. For the majority of the studies, the intervention was implemented by the classroom teacher. In addition, of the 24 studies, three quarters took place in some of the most restrictive settings available for students with EBD. Overall, peer mediated interventions demonstrated medium effect size gains (Percent of non-overlapping data [PND] 83%; Standard Mean Difference [SMD] 2.03; Tau U 0.77).
When assessing the effectiveness of peer-mediated interventions for specific academic content areas, the most consistent gains were observed in spelling (PND 86%; SMD 2.6; Tau-U 0.77), math (PND 92%; SMD 1.68; Tau-U 0.70), reading (PND 80%; SMD 1.83; Tau-U 0.82), and English (PND 69%; SMD 2.10; Tau-U 0.82). 

In addition, results showed that meaningful gains were observed regardless of the role students were assigned, including tutor, tutee, or for students alternating between roles.
AN  - WOS:000413990300004
AU  - Dunn,
AU  - M.
AU  - E.
AU  - Shelnut,
AU  - J.
AU  - Ryan,
AU  - J.
AU  - B.
AU  - Katsiyannis,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
L1  - internal-pdf://1097506593/Dunn-2017-A Systematic Review of Peer-Mediated.pdf
PY  - 2017
SP  - 497-524
T2  - Education and Treatment of Children
TI  - A Systematic Review of Peer-Mediated Interventions on the Academic Achievement of Students with Emotional/Behavioral Disorders
UR  - &lt;Go to ISI&gt;://WOS:000413990300004
VL  - 40
ER  -
TY  - JOUR
AB  - **Objective**
The objective was twofold: to assess the effect of physical activity (PA) interventions on children&rsquo;s and adolescents&rsquo; cognition and metacognition; and to determine the characteristics of individuals and PA programs that enhance the development of cognitive and metacognitive functions.

**Method**
We systematically searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Web of Science, and PsycINFO databases from their inception to October 16, 2016. Intervention studies aimed at examining the exercise&ndash;cognition interaction at a developmental age were included in this systematic review and meta-analysis. Random-effects models were used to calculate pooled effect size (ES) values and their corresponding 95% CIs. Subgroup analyses were conducted to examine the effect of participants&rsquo; and PA programs&rsquo; characteristics.

**Results**
A total of 36 studies were included in this systematic review and meta-analysis. Pooled ES estimations were as follows: nonexecutive cognitive functions 0.23 (95% CI = 0.09&minus;0.37); core executive functions 0.20 (95% CI = 0.10&minus;0.30), including working memory (0.14 [95% CI = 0.00&minus;0.27]), selective attention&minus;inhibition (0.26 [95% CI = 0.10&minus;0.41]), and cognitive flexibility (0.11 [95% CI = &minus;0.10 to 0.32]); and metacognition 0.23 (95% CI = 0.13&minus;0.32), including higher-level executive functions (0.19 [95% CI = 0.06&minus;0.31]) and cognitive life skills (0.30 [95% CI = 0.15&minus;0.45]).

**Conclusion**
PA benefits several domains of cognition and metacognition in youth. Curricular physical education interventions and programs aimed at increasing daily PA seem to be the most effective.
AU  - Alvarez-Bueno,
AU  - C.
AU  - Pesce,
AU  - C.
AU  - Cavero-Redondo,
AU  - I.
AU  - Sanchez-Lopez,
AU  - M.
AU  - Martinez-Hortelano,
AU  - J.
AU  - A.
AU  - Martinez-Vizcaino,
AU  - V.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jaac.2017.06.012
L1  - internal-pdf://2173471618/Alvarez-Bueno-2017-The effect of physical acti.pdf
N1  - Kristine Ludvigsen (2017-12-13 23:35:36)(Select): litt usikker på hvem disse barna er. men det er relevant tiltak og utfall, så inkl;
PY  - 2017
SP  - 729-738
TI  - The effect of physical activity interventions on children&#039;s cognition and metacognition: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-36326-009
VL  - 56
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The death of a parent is a highly stressful life event for bereaved children. Several studies have shown an increased risk of mental ill-health and psychosocial problems among affected children. The aims of this study were to systematically review studies about effective support interventions for parentally bereaved children and to identify gaps in the research. 

**METHODS: **
The review&#039;s inclusion criteria were comparative studies with samples of parentally bereaved children. The focus of these studies were assessments of the effects on children of a bereavement support intervention. The intervention was directed towards children 0-18 years; but it could also target the children&#039;s remaining parent/caregiver. The study included an outcome measure that dealt with effects of the intervention on children. The following electronic databases were searched up to and including November 2015: PubMed, PsycINFO, Cinahl, PILOTS, ProQuest Sociology (Sociological Abstracts and Social Services Abstracts). The included studies were analysed and summarized based on the following categories: type of intervention, reference and grade of evidence, study population, evaluation design, measure, outcome variable and findings as effect size within and between groups.

**RESULTS: **
One thousand, seven hundred and-six abstracts were examined. Following the selection process, 17 studies were included. The included studies consisted of 15 randomized controlled studies, while one study employed a quasi-experimental and one study a pre-post-test design. Thirteen studies provided strong evidence with regards to the quality of the studies due to the grade criteria; three studies provided fairly strong evidence and one study provided weaker evidence. The included studies were published between 1985 and 2015, with the majority published 2000 onwards. The studies were published within several disciplines such as psychology, social work, medicine and psychiatry, which illustrates that support for bereaved children is relevant for different professions. The interventions were based on various forms of support: group interventions for the children, family interventions, guidance for parents and camp activities for children. In fourteen studies, the interventions were directed at both children and their remaining parents. These studies revealed that when parents are supported, they can demonstrate an enhanced capacity to support their children. In three studies, the interventions were primarily directed at the bereaved children. The results showed positive between group effects both for children and caregivers in several areas, namely large effects for children&#039;s traumatic grief and parent&#039;s feelings of being supported; medium effects for parental warmth, positive parenting, parent&#039;s mental health, grief discussions in the family, and children&#039;s health. There were small effects on several outcomes, for example children&#039;s post-traumatic stress disorder (PTSD) symptoms, anxiety, depression, self-esteem and behaviour problems. There were studies that did not show effects on some measures, namely depression, present grief, and for the subgroup boys on anxiety, depression, internalizing and externalizing. 

**CONCLUSIONS: **
The results indicate that relatively brief interventions can prevent children from developing more severe problems after the loss of a parent, such as traumatic grief and mental health problems. Studies have shown positive effects for both children&#039;s and remaining caregiver&#039;s health. Further research is required including how best to support younger bereaved children. There is also a need for more empirically rigorous effect studies in this area.
AN  - 28797262
AU  - Bergman,
AU  - A.
AU  - S.
AU  - Axberg,
AU  - U.
AU  - Hanson,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s12904-017-0223-y
L1  - internal-pdf://3247107564/Bergman-2017-When a parent dies - a systematic.pdf
PY  - 2017
SP  - 39
TI  - When a parent dies - a systematic review of the effects of support programs for parentally bereaved children and their caregivers
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28797262
VL  - 16
ER  -
TY  - JOUR
AB  - **Background**
Young people&rsquo;s risky use of alcohol or recreational drugs, such as cannabis, remains a significant public health issue. Many countries have made substantial efforts to minimize the long-term consequences of alcohol and/or cannabis use at multiple levels, ranging from government policy initiatives to primary health care services.

In this review, we focused on the effects of brief interventions, provided by electronic devices (computerized brief interventions). A brief intervention is defined as any preventive or therapeutic activity delivered by a health worker, psychologist, social worker, or volunteer worker, and given within a maximum of four structured therapy sessions each lasting between five and ten minutes with a maximum total time of one hour. Brief interventions may work by making the clients think differently about their alcohol/cannabis use, and by providing them with skills to change their behavior if they are motivated to change.

A computerized brief intervention, in contrast, is not directly delivered by a human being, but may be delivered through online and offline electronic devices. Such interventions can reach large audiences at a low cost and can simultaneously simulate an &lsquo;interpersonal therapeutic component&rsquo; by targeting recipients&rsquo; feedback.

**Objectives**
To assess the effectiveness of early, computerized brief interventions on alcohol and cannabis use by young people aged 15 to 25 years who are high or risky consumers of either one or both of these substances by synthesizing data from randomized controlled trials.

**Search methods**
We searched 11 electronic databases including MEDLINE, PsycINFO, EMBASE, Cinahl and The Cochrane Library in April 2016 for published, unpublished and ongoing studies using adapted subject headings and a comprehensive list of free-text terms. Additionally, we searched the reference lists of the included studies. We also have set up an EBSCO host alert notification (EPAlerts@EPNET.COM) that continuously surveys the Cochrane Library (including CENTRAL), Medline and Embase. We receive updated searches via email. This search is up to date as of May 2016.

**Selection criteria**
We included all randomized or quasi-randomized controlled trials of any computerized brief intervention used as a stand-alone treatment aimed at reducing alcohol and/or cannabis consumption. Eligible comparators included no intervention, waiting list control or an alternative brief intervention (computerized or non-computerized). Participants were young people between 15 and 25 years of age who were defined as risky consumers of alcohol or cannabis, or both.

**Data collection and analysis**
Two researchers independently screened titles and abstracts against the inclusion criteria. Two researchers independently assessed the full texts of all included articles. We used standard methodological procedures expected by the Campbell Collaboration.

**Results**
We included 60 studies that had randomized 33,316 participants in this review. Study characteristics: The studies were mostly from the United States and targeted high and risky alcohol use among university students. Bias/quality assessment: Some of the studies lacked clear descriptions of how the randomization sequence was generated and concealed. Many of the studies did not blind the participants. Some of the studies suffered from high loss to follow-up, and few studies had a pre-registered protocol. Findings: For alcohol, we found moderate quality evidence that multi-dose assessment and feedback was more effective than a single-dose assessment. We found low quality evidence that assessment and feedback might be more effective than no intervention. Assessment and feedback might also be more effective than assessment alone (low quality evidence). Short-term effects (&lt; 6 months) were mostly larger than long-term (&ge;6 months) effects. For cannabis, we found that assessment and feedback might slightly reduce short-term consumption compared to no intervention. Adding feedback to assessment may have little or no effect on short-term cannabis consumption. Moreover, there may be little or no difference between assessment plus feedback and education on short-term and long-term cannabis consumption. Adverse effects: We did not find evidence of any adverse effects of the interventions.

**Implications for policy, practice and research**
Computerized brief interventions are easy to administer, and the evidence from this review indicates that such brief interventions might reduce drinking for several months after the intervention. Additionally, there is no evidence for adverse effects. This means that brief, computerized interventions could be feasible ways of dealing with risky alcohol use among young people. The evidence on cannabis consumption is scarcer, suggesting the need for more research.
AU  - Smedslund,
AU  - G.
AU  - Wollscheid,
AU  - S.
AU  - Fang,
AU  - L.
AU  - Nilsen,
AU  - W.
AU  - Steiro,
AU  - A.
AU  - Larun,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://campbellcollaboration.org/library/computerised-inteventions-youth-alcohol-cannabis-use.html
PY  - 2017
TI  - Effect of early, brief computerized interventions on risky alcohol and cannabis use among young people
VL  - 13
ER  -
TY  - JOUR
AB  - Children and adolescents are a vulnerable group to develop post-traumatic stress symptoms after natural or man-made disasters. In the light of increasing numbers of refugees under the age of 18 years worldwide, there is a significant need for effective treatments. 

This meta-analytic review investigates specific psychosocial treatments for children and adolescents after man-made and natural disasters. In a systematic literature search using MEDLINE, EMBASE and PsycINFO, as well as hand-searching existing reviews and contacting professional associations, 36 studies were identified. 

Random- and mixed-effects models were applied to test for average effect sizes and moderating variables. Overall, treatments showed high effect sizes in pre-post comparisons (Hedges&#039; g = 1.34) and medium effect sizes as compared with control conditions (Hedges&#039; g = 0.43). 

Treatments investigated by at least two studies were cognitive-behavioural therapy (CBT), eye movement desensitization and reprocessing (EMDR), narrative exposure therapy for children (KIDNET) and classroom-based interventions, which showed similar effect sizes. However, studies were very heterogenic with regard to their outcomes. 

Effects were moderated by type of profession (higher level of training leading to higher effect sizes). A number of effective psychosocial treatments for child and adolescent survivors of disasters exist. CBT, EMDR, KIDNET and classroom-based interventions can be equally recommended. Although disasters require immediate reactions and improvisation, future studies with larger sample sizes and rigorous methodology are needed.
AN  - 28397633
AU  - Brown,
AU  - R.
AU  - C.
AU  - Witt,
AU  - A.
AU  - Fegert,
AU  - J.
AU  - M.
AU  - Keller,
AU  - F.
AU  - Rassenhofer,
AU  - M.
AU  - Plener,
AU  - P.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1017/S0033291717000496
L1  - internal-pdf://1258007003/Brown-2017-Psychosocial interventions for chil.pdf
PY  - 2017
SP  - 1893-1905
TI  - Psychosocial interventions for children and adolescents after man-made and natural disasters: a meta-analysis and systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28397633
VL  - 47
ER  -
TY  - JOUR
AB  - **Introduction**
Tobacco remains the key modifiable risk factor for the development of a number of diseases, including cardiovascular disease, cerebrovascular disease, lower respiratory infections, chronic obstructive pulmonary disease, tuberculosis and cancer. Among priority populations, smoking prevalence remains high, smokers tend to relapse more often and earlier and fewer are able to sustain quit attempts. This systematic review provides an update on the literature. Areas covered: Twenty-four randomized controlled trials published from 2010-2017, in English language, were identified after searching on Medline, Ovid, Embase and PsycINFO databases. Studies reported on the effectiveness of smoking cessation interventions among six disadvantaged groups known to have high smoking rates: (i) homeless, (ii) prisoners, (iii) indigenous populations, (iv) at-risk youth, (v) people with low income, and (vi) those with a mental illness. Narrative review and assessment of methodological quality of included papers was undertaken. Expert commentary: There is a growing evidence base of methodologically robust studies evaluating a variety of behavioural smoking cessation interventions for priority populations. Multi-component interventions and those examining behavioural interventions incorporating mindfulness training, financial incentives, motivational interviewing and extended telephone-delivered counseling may be effective in the short-term, particularly for smokers on low incomes and people with a mental illness. Copyright &copy; 2017 Informa UK Limited, trading as Taylor &amp; Francis Group.
AN  - 617267097
AU  - Wilson,
AU  - A.
AU  - Guillaumier,
AU  - A.
AU  - George,
AU  - J.
AU  - Denham,
AU  - A.
AU  - Bonevski,
AU  - B.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1080/17476348.2017.1340836
L1  - internal-pdf://0702193734/Wilson-2017-A systematic narrative review of t.pdf
PY  - 2017
SP  - 617-630
T2  - Expert Review of Respiratory Medicine
TI  - A systematic narrative review of the effectiveness of behavioural smoking cessation interventions in selected disadvantaged groups (2010-2017)
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18&amp;AN=617267097
UR  - https://www.tandfonline.com/doi/full/10.1080/17476348.2017.1340836
VL  - 11(8)
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Substance consumption (SC) begins in adolescence and has been linked to protection factors such as family relationships (FR) and positive parenting (PP). There are few studies concerning the effectiveness of prevention programs based on the family, even though assessing interventions is one of the objectives of preventive science. The aim of this study was to analyze the evidence on family-based selective prevention programs in relation to drug consumption in adolescents.

**METHODOLOGY:**
A meta-analysis of 9 studies with 102 measures grouped in three dimensions, FR, PP and SC, ranging between 2001 and 2015, was conducted.RESULTS: Effect sizes (ES) were found to be 0.82 for FR, 0.71 for PP, 0.77 for the combination of both and 0.21 for SC. The Q and I2 indexes expressed high heterogeneity.

**CONCLUSIONS: **
Despite obtaining high ES consistent with previous studies, the great heterogeneity found did not allow us to draw clear conclusions regarding the primary studies. It is recommended that methodological improvements in assessment and reporting processes be carried out for future comparisons.
AD  - Valero de Vicente, Maria. Universidad de las Islas Baleares.
AN  - 28693698
AU  - Valero
AU  - de
AU  - Vicente,
AU  - M.
AU  - Ballester
AU  - Brage,
AU  - L.
AU  - Orte
AU  - Socias,
AU  - M.
AU  - C.
AU  - Amer
AU  - Fernandez,
AU  - J.
AU  - A.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.7334/psicothema2016.275
DP  - Ovid Technologies
J2  - Psicothema
KW  - Adolescent
KW  - Family Relations
KW  - Health Promotion
KW  - Humans
KW  - *Parenting
KW  - *Substance-Related Disorders/pc [Prevention &amp; Control]
L1  - internal-pdf://3109301627/Valero de Vicen-2017-Meta-analysis of family-b.pdf
LA  - English
M3  - Meta-Analysis
N1  - Valero de Vicente, MariaBallester Brage, LluisOrte Socias, Maria CAmer Fernandez, Joan A
PY  - 2017
SP  - 299-305
T2  - Psicothema
TI  - Meta-analysis of family-based selective prevention programs for drug consumption in adolescence
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=28693698
VL  - 29
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering om effektene av tiltaket International Child Development Programme (ICDP) i Norge. Artikkelen er en revisjon av en tidligere beskrivelse av det samme tiltaket i Ungsinn (Reedtz, 2009). ICDP er et foreldreveiledningsprogram som søker å støtte barns psykososiale utvikling gjennom styrking av omsorgspersonens kompetanse i deres omsorgsutøvelse for barn. ICDP er et lavterskel, tidsavgrenset og strukturert veiledningstiltak for omsorgspersoner for barn i alderen 0-18 år. Tiltaket er utviklet av Karsten Hundeide og Henning Rye. Tiltakseier i Norge er Bufdir og ICDP Norge. ICDP blir gjennomført på de arenaer der barnet og dets omsorgsgivere holder til i lokalmiljøet samt i fengsel dersom omsorgsgiver/e er fengslet.

METODE
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline, PsycINFO, Norart, Cochrane, Cristin, Nora, Scopus og Swemed. Fem artikler basert på delvis samme utvalg tilfredsstilte inklusjonskriteriene.

RESULTATER
Resultatene omfatter en oppsummering av tiltakets beskrivelse, inkluderte effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. ICDPs målsettinger, tiltaksarenaer, utforming og metoder er beskrevet. Det foreligger &eacute;n studie som gjennom to artikler har undersøkt tiltakets effekt i norsk kontekst. Disse benyttet et kvasi-eksperimentelt design og bygger på pre- og posttestmålinger (artikkel 1), samt måling mellom 6 og12 måneder etter avsluttet intervensjon (artikkel 2). I tillegg er det tre artikler der ulike grupper er sammenlignet før og etter deltakelse i ICDP. Totalt sett var det ingen effekt for de fleste utfallsvariabler som ble målt på tvers av studiene. Resultatene viste noen små positive effekter for enkelte utfallsmål knyttet til foreldreatferd (f.eks. Foreldrestrategi, Håndtering av barnet og Engasjement i barnet), vansker hos barnet (f.eks. SDQ Innvirkning på barnet og SDQ Total) og foreldres psykososiale helse. Studiene er imidlertid utført med svak forskningsmetodisk kvalitet og dette skaper usikkerhet om hvorvidt effektene er reelle og kan tilskrives tiltaket. Tiltaket har noen rutiner for å kvalitetssikre implementeringen, men ingen helhetlig strategi for dette eller spredning av tiltaket.

KONKLUSJON
Basert på Ungsinns kriterier klassifiseres ICDP på evidensnivå 3 &ndash; Tiltak med noe dokumentasjon på effekt.
AU  - Reedtz,
AU  - C.,
AU  - Lauritzen,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2017
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: ICDP (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/icdp-2-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - In the past 10 years, mental and behavioral health has seen a proliferation of technology-based interventions in the form of online and other computer-delivered programs. This paper focuses on technology-based treatment and preventive interventions aimed at benefitting children and adolescents via either involving the parents and families, or only the youth. The review considered only technology-based interventions that had at least one published study with a randomized controlled trial design. 

Questions being addressed included: (1) What are the technology-based interventions in the mental/behavioral health area that have been systematically evaluated in published studies? (2) What are the common and unique characteristics of these interventions and their application with respect to sample characteristics, target problems, and technology characteristics (platforms, structures, elements, and communication formats)? and (3) Which intervention approaches and strategies have accrued the greatest evidence? 

The review identified 30 technology-based psychosocial interventions for children and families, 19 of which were parent or family-focused (32 studies) and 11 of which were youth-focused (in 13 studies). For the parent/family-focused interventions, greatest promise was found in those that addressed either youth behavioral problems or depressive/anxious symptoms, as well as more general bolstering of parenting efficacy. 

The youth-focused interventions showed some promise in reducing depressive/anxious symptoms. Advantages and disadvantages of the technology-based approaches were considered, and areas for future research and development were discussed.
AN  - 27787701
AU  - MacDonell,
AU  - K.
AU  - W.
AU  - Prinz,
AU  - R.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-016-0218-x
L1  - internal-pdf://2708473389/MacDonell-2017-A Review of Technology-Based Yo.pdf
PY  - 2017
SP  - 185-200
TI  - A Review of Technology-Based Youth and Family-Focused Interventions
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27787701
VL  - 20
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
This meta-analysis examined group-design studies investigating the effectiveness of Daily Behavior Report Cards (DBRC) as a school-based intervention to manage the classroom behavior of students with ADHD. 

**METHODS: **
A search of three article databases (PsycINFO, ERIC and Medline) identified seven group design evaluations of DBRC interventions. This meta-analysis included a total of 272 participants, with an average age of 7.9 years old. Three of the studies compared a control group to a treatment group with randomized group assignment, one study compared a control group to three treatment groups, two studies compared pre-and post-treatment scores in the same group, and one study compared pre-and post-treatment results of two intervention groups without random assignment. Dependent measures for these studies were teacher ratings (n = 5) and systematic direct observation of student academic and social behaviour (n = 2). Standardized mean differences ( Hedge&#039;s g) were calculated to obtain a pooled effect size using fixed effects. 

**RESULTS: **
DBRCs were associated with reductions teacher-rated ADHD symptoms, with a Hedge&#039;s g of 0.36 (95% CI: 0.12-0.60, z=2.93, p &lt;= .005) with low heterogeneity (Q-value: 2.40, I = 0.00). This result excluded two studies that used observational coding instead of standardized tests to evaluate the effects of the intervention. A moderator analysis indicated that the effect size for systematic direct observation was large ( Hedge&#039;s G = 1.05[95% CI: 0.66-1.44, z=5.25, p &lt;= .00]), with very high heterogeneity (Q-value: 46.34, I: 93.53). A second moderator analysis found differences in the effects of DBRCs for comorbid externalizing symptoms with an overall effect size of 0.34 (95%CI: -0.04-0.72, z=1.76 p =0.08) with high heterogeneity (Q-value: 3.98, I&lt;sup&gt;2&lt;/sup&gt;: 74.85). 

**CONCLUSIONS: **
DBRCs effectively reduce the frequency and severity of ADHD symptoms in classroom settings. Additionally, they have a significant effect on co-occuring externalizing behaviors. It appears that systematic direct observation may be a more sensitive measure of treatment effects compared to teacher ratings of ADHD symptoms.
AN  - 29135352
AU  - Iznardo,
AU  - M.
AU  - Rogers,
AU  - M.
AU  - A.
AU  - Volpe,
AU  - R.
AU  - J.
AU  - Labelle,
AU  - P.
AU  - R.
AU  - Robaey,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1087054717734646
L1  - internal-pdf://3616545884/Iznardo-2017-The Effectiveness of Daily Behavi.pdf
PY  - 2017
SP  - 1087054717734646
T2  - Journal of Attention Disorders
TI  - The Effectiveness of Daily Behavior Report Cards for Children With ADHD: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29135352
ER  -
TY  - JOUR
AB  - There is a need for evidence based interventions for children with autism spectrum disorder (ASD) to limit the life-long, psychosocial impact of pragmatic language impairments. 

This systematic review identified 22 studies reporting on 20 pragmatic language interventions for children with ASD aged 0-18 years. The characteristics of each study, components of the interventions, and the methodological quality of each study were reviewed. Meta-analysis was conducted to assess the effectiveness of 15 interventions. 

Results revealed some promising approaches, indicating that active inclusion of the child and parent in the intervention was a significant mediator of intervention effect. 

Participant age, therapy setting or modality were not significant mediators between the interventions and measures of pragmatic language. The long-term effects of these interventions and the generalisation of learning to new contexts is largely unknown. Implications for clinical practice and directions for future research are discussed. 

Copyright &copy; 2017 Parsons et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AN  - 615495679
AU  - Parsons,
AU  - L.
AU  - Cordier,
AU  - R.
AU  - Munro,
AU  - N.
AU  - Joosten,
AU  - A.
AU  - Speyer,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0172242
L1  - internal-pdf://0930094998/Parsons-2017-A systematic review of pragmatic.pdf
PY  - 2017
TI  - A systematic review of pragmatic language interventions for children with autism spectrum disorder
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0172242&amp;type=printable
VL  - 12 (4) (no pagination)
ER  -
TY  - JOUR
AB  - This meta-analysis reviewed 82 school-based, universal social and emotional learning (SEL) interventions involving 97,406 kindergarten to high school students (M&lt;sub&gt;age&lt;/sub&gt; = 11.09 years; mean percent low socioeconomic status = 41.1; mean percent students of color = 45.9). 

Thirty-eight interventions took place outside the United States. Follow-up outcomes (collected 6 months to 18 years postintervention) demonstrate SEL&#039;s enhancement of positive youth development. 

Participants fared significantly better than controls in social-emotional skills, attitudes, and indicators of well-being. Benefits were similar regardless of students&#039; race, socioeconomic background, or school location. 

Postintervention social-emotional skill development was the strongest predictor of well-being at follow-up. Infrequently assessed but notable outcomes (e.g., graduation and safe sexual behaviors) illustrate SEL&#039;s improvement of critical aspects of students&#039; developmental trajectories.
AN  - 28685826
AU  - Taylor,
AU  - R.
AU  - D.
AU  - Oberle,
AU  - E.
AU  - Durlak,
AU  - J.
AU  - A.
AU  - Weissberg,
AU  - R.
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/cdev.12864
L1  - internal-pdf://3900165692/Taylor-2017-Promoting Positive Youth Developme.pdf
PY  - 2017
SP  - 1156-1171
TI  - Promoting Positive Youth Development Through School-Based Social and Emotional Learning Interventions: A Meta-Analysis of Follow-Up Effects
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28685826
VL  - 88
ER  -
TY  - JOUR
AB  - Twenty-one clinical trials were synthesized using a random-effects model, which substantiated that counseling generally produces a medium effect in treating conduct disorder in youth at termination (d+ = 0.30 to 0.57; k = 28). 

However, the lasting effects at follow-up were unclear because few follow-up studies (k = 13) have been conducted (d+ = -0.53 to 0.58), and only 2 randomized controlled follow-up studies were located. 

No effects of moderating variables were evident. Implications for counseling practice and outcome research are addressed.
AN  - WOS:000392432800004
AU  - Erford,
AU  - B.
AU  - T.
AU  - Bardhoshi,
AU  - G.
AU  - Ross,
AU  - M.
AU  - Gunther,
AU  - C.
AU  - Duncan,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/jcad.12115
L1  - internal-pdf://1581537955/Erford-2017-Meta-Analysis of Counseling Outcom.pdf
PY  - 2017
SP  - 35-44
TI  - Meta-Analysis of Counseling Outcomes for Youth With Conduct Disorders
UR  - &lt;Go to ISI&gt;://WOS:000392432800004
VL  - 95
ER  -
TY  - JOUR
AB  - Research on the effects of physical activity on children with attention deficit hyperactivity disorder is promising, yet no attempt has been made to integrate current findings using meta-analytic techniques. 

Using a meta-regression, the present study examined the effectives of physical activity for children with attention deficit hyperactivity disorder on a number of cognitive, behavioral, and emotional outcomes. 

From 20 empirical studies, 164 effect sizes quantifying the effectiveness of physical activity for children with attention deficit hyperactivity disorder were extracted from 22 independent samples. 

Results indicated an overall moderate-to-large effect for physical activity on children with attention deficit hyperactivity disorder, with a significant effect for emotion/mood. Limitations of the study, future directions, and implications for school professionals are discussed. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-04727-004
AU  - Cornelius,
AU  - C.
AU  - Fedewa,
AU  - A.
AU  - L.
AU  - Ahn,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15377903.2016.1265622
L1  - internal-pdf://3392762486/Cornelius-2017-The effect of physical activity.pdf
PY  - 2017
SP  - 136-170
TI  - The effect of physical activity on children with ADHD: A quantitative review of the literature
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-04727-004
VL  - 33
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Multidimensional family therapy (MDFT) is a well-established treatment for adolescents showing both substance abuse and/or antisocial behavior. 

**METHOD:**
The effectiveness of MDFT in reducing adolescents&#039; substance abuse, delinquency, externalizing and internalizing psychopathology, and family malfunctioning was examined by means of a (three-level) meta-analysis, summarizing 61 effect sizes from 19 manuscripts (N = 1,488 participants). 

**RESULTS:** 
Compared with other therapies, the overall effect size of MDFT was significant, albeit small in magnitude (d = 0.24, p &lt; .001), and similar across intervention outcome categories. Moderator analysis revealed that adolescents with high severity problems, including severe substance abuse and disruptive behavior disorder, benefited more from MDFT than adolescents with less severe conditions. 

**CONCLUSIONS: **
It can be concluded that MDFT is effective for adolescents with substance abuse, delinquency, and comorbid behavior problems. Subsequently, it is important to match specific characteristics of the adolescents, such as extent of impairment, with MDFT.
AN  - 28121012
AU  - van
AU  - der
AU  - Pol,
AU  - T.
AU  - M.
AU  - Hoeve,
AU  - M.
AU  - Noom,
AU  - M.
AU  - J.
AU  - Stams,
AU  - G.
AU  - Doreleijers,
AU  - T.
AU  - A.
AU  - H.
AU  - van
AU  - Domburgh,
AU  - L.
AU  - Vermeiren,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.12685
L1  - internal-pdf://2005073722/van der Pol-2017-Research Review_ The effectiv.pdf
PY  - 2017
SP  - 532-545
TI  - Research Review: The effectiveness of multidimensional family therapy in treating adolescents with multiple behavior problems - a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med8&amp;AN=28121012
VL  - 58
ER  -
TY  - JOUR
AB  - The aims are to evaluate the efficacy and safety of aripiprazole for tic disorders (TDs) in children and adolescents. 

We searched PubMed, Embase, PsychINFO, Cochrane database as well as Chinese databases of CNKI, VIP, CBM and Wanfang from the database inception to October 2016, and 17 full-text studies (N=1305) were included in our article. The meta-analysis of 10 studies (N=817) showed that there was no significant difference in the reduction of total YGTSS score between aripiprazole and other drugs, and meta-analysis of 7 studies (n=324) which used tic symptom control 30% as outcome measure showed that there was no significant difference between aripiprazole and other treatments. 

The most common AEs of aripiprazole were the drowsiness, nausea/vomiting and increased appetite, and meta analysis which used the TESS scale as the outcome measurement showed that there was a significant difference between aripiprazole and haloperidol. In conclusion, these data provide moderate quality evidence that aripiprazole could be an effective and safe treatment option for TDs, and results from further trials are urgently needed to extend this evidence base. 

Copyright &copy; 2017 Elsevier Ireland Ltd
AN  - 615514886
AU  - Wang,
AU  - S.
AU  - Wei,
AU  - Y.
AU  - Z.
AU  - Yang,
AU  - J.
AU  - H.
AU  - Zhou,
AU  - Y.
AU  - M.
AU  - Cheng,
AU  - Y.
AU  - H.
AU  - Yang,
AU  - C.
AU  - Zheng,
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.psychres.2017.04.013
L1  - internal-pdf://0058731353/Wang-2017-The efficacy and safety of aripipraz.pdf
PY  - 2017
SP  - 24-32
TI  - The efficacy and safety of aripiprazole for tic disorders in children and adolescents: A systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/psychres
VL  - 254
ER  -
TY  - JOUR
AB  - **Introduction: **
The development and use of serious games for mental health disorders are on the rise. Yet, little is known about the impact of these games on clinical mental health symptoms. We conducted a systematic review and meta-analysis of randomized controlled trials that evaluated the effectiveness of serious games on symptoms of mental disorder. 

**Method: **
We conducted a systematic search in the PubMed, PsycINFO, and Embase databases, using mental health and serious games-related keywords. Ten studies met the inclusion criteria and were included in the review, and nine studies were included in the meta-analysis. 

**Results:** 
All of the serious games were provided via personal computer, mostly on CD-ROM without the need for an internet connection. The studies targeted age groups ranging from 7 to 80 years old. The serious games focused on symptoms of depression (n = 2), post-traumatic stress disorder (n = 2), autism spectrum disorder (n = 2), attention deficit hyperactivity disorder (n = 1), cognitive functioning (n = 2), and alcohol use disorder (n = 1). The studies used goal-oriented (n = 4) and cognitive training games (n = 6). A total of 674 participants were included in the meta-analysis (380 in experimental and 294 in control groups). A meta-analysis of 9 studies comprising 10 comparisons, using a random effects model, showed a moderate effect on improvement of symptoms [g = 0.55 (95% confidence interval 0.28-0.83); P &lt; 0.001], favoring serious games over no intervention controls. 

**Discussion/conclusion: **
Though the number of comparisons in the meta-analysis was small, these findings suggest that serious gaming interventions may be effective for reducing disorder-related symptoms. More studies are needed in order to attain deeper knowledge of the efficacy for specific mental disorders and the longer term effects of this new type of treatment for mental disorders. 

Copyright &copy; 2017 Lau, Smit, Fleming and Riper.
AN  - 614347646
AU  - Lau,
AU  - H.
AU  - M.
AU  - Smit,
AU  - J.
AU  - H.
AU  - Fleming,
AU  - T.
AU  - M.
AU  - Riper,
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3389/fpsyt.2016.00209
L1  - internal-pdf://1413685641/Lau-2017-Serious games for mental health_ Are.pdf
PY  - 2017
TI  - Serious games for mental health: Are they accessible, feasible, and effective? A systematic review and meta-analysis
UR  - http://journal.frontiersin.org/article/10.3389/fpsyt.2016.00209/full
VL  - 7 (JAN) (no pagination)
ER  -
TY  - JOUR
AB  - Adolescent substance use continues to be a significant public health problem. Parent training interventions are effective preventive strategies to reduce youth substance use. However, little is known about differences in effectiveness for youth across demographic characteristics. 

This review assessed the effectiveness of parent training programs at reducing adolescent substance use by participant gender, age, and race/ethnicity. Pubmed/MEDLINE, ERIC, CINAHL, and PsycINFO were searched from database origin to October 31, 2016. 

We included randomized controlled trials that evaluated parent training interventions; reported youth initiation or use of tobacco, alcohol, or other illicit substances; and included adolescents aged 10 to 19. Two independent reviewers extracted data. Disagreements were resolved by consensus or a third researcher. 

Data were synthesized using harvest plots stratified by participant demographics. A total of 1806 publications were identified and reviewed; 38 unique studies were included. Risk of bias of included studies was high. No studies targeted male teens or youth in late adolescence. Few studies targeted Asian-American, Black/African-American, or Hispanic/Latino adolescents. 

Overall, interventions including male and female youth and youth in early adolescence (age 10 to 14 or in 5th to 8th grade) were more beneficial than interventions including female-only or both young and older adolescents. Programs tailored to specific racial/ethnic groups, as well as programs designed for youth from multiple races/ethnic groups, were effective.

Current evidence supports the benefits of offering parenting guidance to all families with adolescent children, regardless of the gender, age, or race/ethnicity of the adolescent.
AN  - 29150747
AU  - Garcia-Huidobro,
AU  - D.
AU  - Doty,
AU  - J.
AU  - L.
AU  - Davis,
AU  - L.
AU  - Borowsky,
AU  - I.
AU  - W.
AU  - Allen,
AU  - M.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s11121-017-0853-6
L1  - internal-pdf://4258036463/Garcia-Huidobro-2017-For Whom Do Parenting Int.pdf
PY  - 2017
SP  - 18
T2  - Prevention Science
TI  - For Whom Do Parenting Interventions to Prevent Adolescent Substance Use Work?
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29150747
VL  - 18
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Although previous studies on information and communication technology (ICT)-based intervention on mental health among adolescents with depressive symptoms have already been combined in a number of systematic reviews, coherent information is still missing about interventions used, participants&#039; engagement of these interventions, and how these interventions work.

**OBJECTIVE: **
We conducted a systematic review and meta-analysis of trials to describe the effectiveness of Web-based interventions to support adolescents with depression or depressive symptoms, anxiety, and stress. We also explored the content of the interventions, as there has previously been a lack of coherent understanding of the detailed content of the Web-based interventions for these purposes. 

**METHODS: **
We included parallel randomized controlled trials targeted at adolescents, or young people in the age range of 10 and 24 years, with symptoms or diagnoses of depression and anxiety. The interventions were from original studies aimed to support mental health among adolescents, and they were delivered via Web-based information and communication technology. 

**RESULTS: **
Out of 2087 records identified, 27 papers (22 studies) met the inclusion criteria. On the basis of a narrative analysis of 22 studies, a variety of Web-based interventions were found; the most commonly used intervention was based on cognitive behavioral therapy. Meta-analysis was further conducted with 15 studies (4979 participants). At the end of the intervention, a statistically significant improvement was found in the intervention group (10 studies) regarding depressive symptoms (P=.02, median 1.68, 95% CI 3.11-0.25) and after 6 months (3 studies; P=.01, median 1.78, 95% CI 3.20-0.37). Anxiety symptoms (8 studies; P&lt;.001, median 1.47, 95% CI 2.36-0.59) and moods and feelings (2 studies; P=.04, median 5.55, 95% CI 10.88-0.22) improved as well in the Web-based intervention group, but there was no difference in stress scores. However, adolescents in the intervention group left the study early more often, both in short-term studies (11 studies; P=.007, median 1.31, 95% CI 1.08-1.58) and mid-term studies (3 studies; P=.02, median 1.65, 95% CI 1.09-2.49). We did not find any studies that had assessed the costs of the Web-based interventions. 

**CONCLUSIONS: **
Despite widely reported promises that information technology use is beneficial to adolescents with depression, the results of our review show only short-term effects on adolescents&#039; mental well-being, whereas long-term effects remain questionable because of the limited number of studies reviewed. Information about the economic benefits of Web-based interventions is still lacking. The quality of the studies, especially biases related to attrition rates and selective reporting, still needs serious attention.
AN  - 29222079
AU  - Valimaki,
AU  - M.
AU  - Anttila,
AU  - K.
AU  - Anttila,
AU  - M.
AU  - Lahti,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2196/mhealth.8624
L1  - internal-pdf://2114035754/Valimaki-2017-Web-Based Interventions Supporti.pdf
PY  - 2017
SP  - e180
T2  - JMIR MHealth and UHealth
TI  - Web-Based Interventions Supporting Adolescents and Young People With Depressive Symptoms: Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29222079
VL  - 5
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
Alcohol use disorders (AUD) place a significant burden on individuals and society. The emergency department (ED) offers a unique opportunity to address AUD with brief screening tools and early intervention. We undertook a systematic review of the effectiveness of ED brief interventions for patients identified through screening who are at risk for AUD, and the effectiveness of these interventions at reducing alcohol intake and preventing alcohol-related injuries. 

**METHODS: **
We conducted systematic electronic database searches to include randomized controlled trials of AUD screening, brief intervention, referral, and treatment (SBIRT), from January 1966 to April 2016. Two authors graded and abstracted data from each included paper. 

**RESULTS: **
We found 35 articles that had direct relevance to the ED with enrolled patients ranging from 12 to 70 years of age. Multiple alcohol screening tools were used to identify patients at risk for AUD. Brief intervention (BI) and brief motivational intervention (BMI) strategies were compared to a control intervention or usual care. Thirteen studies enrolling a total of 5,261 participants reported significant differences between control and intervention groups in their main alcohol-outcome criteria of number of drink days and number of units per drink day. Sixteen studies showed a reduction of alcohol consumption in both the control and intervention groups; of those, seven studies did not identify a significant intervention effect for the main outcome criteria, but nine observed some significant differences between BI and control conditions for specific subgroups (i.e., adolescents and adolescents with prior history of drinking and driving; women 22 years old or younger; low or moderate drinkers); or secondary outcome criteria (e.g. reduction in driving while intoxicated). 

**CONCLUSION:** 
Moderate-quality evidence of targeted use of BI/BMI in the ED showed a small reduction in alcohol use in low or moderate drinkers, a reduction in the negative consequences of use (such as injury), and a decline in ED repeat visits for adults and children 12 years of age and older. BI delivered in the ED appears to have a short-term effect in reducing at-risk drinking.
AN  - 29085549
AU  - Barata,
AU  - I.
AU  - A.
AU  - Shandro,
AU  - J.
AU  - R.
AU  - Montgomery,
AU  - M.
AU  - Polansky,
AU  - R.
AU  - Sachs,
AU  - C.
AU  - J.
AU  - Duber,
AU  - H.
AU  - C.
AU  - Weaver,
AU  - L.
AU  - M.
AU  - Heins,
AU  - A.
AU  - Owen,
AU  - H.
AU  - S.
AU  - Josephson,
AU  - E.
AU  - B.
AU  - Macias-Konstantopoulos,
AU  - W.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.5811/westjem.2017.7.34373
L1  - internal-pdf://4252237049/Barata-2017-Effectiveness of SBIRT for Alcohol.pdf
PY  - 2017
SP  - 1143-1152
TI  - Effectiveness of SBIRT for Alcohol Use Disorders in the Emergency Department: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29085549
VL  - 18
ER  -
TY  - JOUR
AB  - This systematic review evaluates the efficacy of parenting interventions on parent, infant and parent-infant relationship outcome measures for parents of infants under 12 months old. Parent outcomes examined included competence, and confidence; baby outcomes included infant behaviours of crying, settling, and sleeping problems and parent-infant relationship outcomes included parental responsiveness. 

Systematic searches of five databases were carried out. In total, 36 randomised controlled trials over the past 35 years were included in the meta-analyses, with a total of 4880 participants. Interventions were carried out either during pregnancy or within the first 12 months after birth and involved teaching specific strategies and provision of information on infant development and behaviour. 

Mean effect sizes were obtained using a structural equation modelling (SEM) approach to meta-analysis. Heterogeneity was found on parent responsiveness and infant sleep. Potential moderator variables were assessed for these two outcomes using the SEM approach. 

Results showed that early parenting interventions are effective in improving parental responsiveness (d = 0.77), and improving or preventing infant sleep problems (d = 0.24), but not crying problems (d = 0.27) possibly due to low power. No conclusions could be drawn in regards to parental competence or confidence. Moderator analysis showed that for interventions aimed at improving responsiveness, briefer interventions were more effective than longer ones; and studies published more recently reported smaller effects than older studies. 

No other moderators influenced the assessed intervention outcomes. The findings of this study provide further evidence for the positive effects of early parenting interventions for infants under 12 months of age, however future research is needed to assess intervention effects on parental competence and confidence. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-09996-001
AU  - Mihelic,
AU  - M.
AU  - Morawska,
AU  - A.
AU  - Filus,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10826-017-0675-y
L1  - internal-pdf://3445146358/Mihelic-2017-Effects of early parenting interv.pdf
PY  - 2017
SP  - 1507-1526
TI  - Effects of early parenting interventions on parents and infants: A meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-09996-001
VL  - 26
ER  -
TY  - GEN
AB  - **Background:** 
Increasing evidence indicates that individuals who develop severe mental illness (SMI) are also vulnerable to developing post-traumatic stress disorder (PTSD), due to increased risk of exposure to traumatic events and social adversity. The effectiveness of trauma-focused psychological interventions (TFPIs) for PTSD in the general population is well-established. TFPIs involve identifying and changing unhelpful beliefs about traumatic experiences, processing of traumatic memories, and developing new ways of responding to cues associated with trauma. Little is known about the potential feasibility, acceptability and effectiveness of TFPIs for individuals who have a SMI and PTSD.Objectives: To evaluate the effectiveness of psychological interventions for PTSD symptoms or other symptoms of psychological distress arising from trauma in people with SMI.

**Search methods:** 
We searched the Cochrane Schizophrenia Group?s Trials Study-Based Register (up until March 10, 2016), screened reference lists of relevant reports and reviews, and contacted trial authors for unpublished and/or specific outcome data.

**Selection criteria:** 
We included all relevant randomised controlled trials (RCTs) which investigated TFPIs for people with SMI and PTSD, and reported useable data.Data collection and analysis: Three review authors (DS, MF, IN) independently screened the titles and abstracts of all references identified, and read short-listed full text papers. We assessed risk of bias in each case. We calculated the risk ratio (RR) and 95% confidence interval (CI) for binary outcomes, and the mean difference (MD) and 95% CI for continuous data, on an intention-to-treat basis. We assessed quality of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) and created &#039;Summary of findings&#039; tables.

**Main results:** 
Four trials involving a total of 300 adults with SMI and PTSD are included. These trials evaluated three active intervention therapies: trauma-focused cognitive behavioural therapy (TF-CBT), eye movement desensitisation and reprocessing (EMDR), and brief psychoeducation for PTSD, all delivered via individual sessions. Our main outcomes of interest were PTSD symptoms, quality of life/well-being, symptoms of co-morbid psychosis, anxiety symptoms, depressive symptoms, adverse events and health economic outcomes. 1. TF-CBT versus usual care/waiting listThree trials provided data for this comparison, however, continuous outcome data available were more often found to be skewed than unskewed, leading to the necessity of conducting analyses separately for the two types of continuous data. Using the unskewed data only, results showed no significant differences between TF-CBT and usual care in reducing clinician-rated PTSD symptoms at short term (1 RCT, n =13, MD 13.15, 95% CI -4.09 to 30.39,low-quality evidence). Limited unskewed data showed equivocal results between groups in terms of general quality of life (1 RCT, n = 39, MD -0.60, 95% CI -4.47 to 3.27, low-quality evidence), symptoms of psychosis (1 RCT, n = 9, MD -6.93, 95% CI -34.17 to 20.31, low-quality evidence), and anxiety (1 RCT, n = 9, MD 12.57, 95% CI -5.54 to 30.68, very low-quality evidence), at medium term. The only available data on depression symptoms were skewed and were equivocal across groups at medium term (2 RCTs, n = 48, MD 3.26, 95% CI -3.66 to 10.18, very low-quality evidence). TF-CBT was not associated with more adverse events (1 RCT, n = 100, RR 0.44, 95% CI 0.09 to 2.31, low-quality evidence) at medium term. No data were available for health economic outcomes. Very limited data for PTSD and other symptoms were available over the long term. 2. EMDR versus waiting listOne trial provided data for this comparison. Favourable effects were found for EMDR in terms of PTSD symptom severity at medium term but data were skewed (1 RCT, n = 83, MD -12.31, 95% CI -22.72 to -1.90, very low-quality evidence). EMDR was not associated with more adverse events (1 RCT, n = 102, RR 0.21, 95% CI 0.02 to 1.85, low-quality evidence). No data were avai able for quality of life, symptoms of co-morbid psychosis, depression, anxiety and health economics.3. TF-CBT versus EMDROne trial compared TF-CBT with EMDR. PTSD symptom severity, based on skewed data (1 RCT, n = 88, MD -1.69, 95% CI -12.63 to 9.23, very low-quality evidence) was similar between treatment groups. No data were available for the other main outcomes.4. TF-CBT versus psychoeducationOne trial compared TF-CBT with psychoeducation. Results were equivocal for PTSD symptom severity (1 RCT, n = 52, MD 0.23, 95% CI -14.66 to 15.12, low-quality evidence) and general quality of life (1 RCT, n = 49, MD 0.11, 95% CI -0.74 to 0.95, low-quality evidence) by medium term. No data were available for the other outcomes of interest.

**Authors&#039; conclusions:** 
Very few trials have investigated TFPIs for individuals with SMI and PTSD. Results from trials of TF-CBT are limited and inconclusive regarding its effectiveness on PTSD, or on psychotic symptoms or other symptoms of psychological distress. Only one trial evaluated EMDR and provided limited preliminary evidence favouring EMDR compared to waiting list. Comparing TF-CBT head-to-head with EMDR and brief psychoeducation respectively, showed no clear effect for either therapy. Both TF-CBT and EMDR do not appear to cause more (or less) adverse effects, compared to waiting list or usual care; these findings however, are mostly based on low to very low-quality evidence. Further larger scale trials are now needed to provide high-quality evidence to confirm or refute these preliminary findings, and to establish which intervention modalities and techniques are associated with improved outcomes, especially in the long term.
AN  - CD011464
AU  - Sin,
AU  - J.
AU  - Spain,
AU  - D.
AU  - Furuta,
AU  - M.
AU  - Murrells,
AU  - T.
AU  - Norman,
AU  - I.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd011464.pub2
L1  - internal-pdf://2379525677/Sin-2017-Psychological interventions for post-.pdf
PY  - 2017
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological interventions for post-traumatic stress disorder (PTSD) in people with severe mental illness
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD011464.pub2/abstract
UR  - http://onlinelibrary.wiley.com/store/10.1002/14651858.CD011464.pub2/asset/CD011464.pdf?v=1&amp;t=j82wpvq1&amp;s=9e72423f00aa5cf3ac6c28cf7f166acc3ea60a6d
ER  -
TY  - JOUR
AB  - We report a systematic review of moderators of CBT efficacy for pediatric OCD relative to other treatments. CENTRAL, MEDLINE, EMBASE, CINAHL, and PsycINFO were searched for RCTs reporting on effect moderation for CBT outcomes. Five studies (N = 365) examined 17 variables with three significant moderators identified. 

Compared to pill-placebo, CBT monotherapy was not effective for children with a family history of OCD but was for those without a family history. For children with a family history, CBT plus sertraline efficacy was attenuated but remained significant. For children with tics, CBT but not sertraline remained superior to pill-placebo. 

For non-responders to initial treatment with CBT, continuing CBT was inferior to commencing sertraline for those with tics but was not different for those without tics. A supplementary review identified older age, symptom and impairment severity, co-morbidity and family accommodation as consistent predictors of a poorer outcome to CBT. 

Current evidence for moderation effects is post-hoc, from single RCTs, has small Ns and requires replication. The review identifies family history of OCD and the presence of tics as factors requiring further examination in properly conducted trials and about which clinicians need to show care in their treatment recommendations.
AN  - 29287236
AU  - Turner,
AU  - C.
AU  - O&#039;Gorman,
AU  - B.
AU  - Nair,
AU  - A.
AU  - O&#039;Kearney,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.psychres.2017.12.034
L1  - internal-pdf://1895344041/Turner-2017-Moderators and predictors of respo.pdf
PY  - 2017
SP  - 50-60
T2  - Psychiatry Research
TI  - Moderators and predictors of response to cognitive behaviour therapy for pediatric obsessive-compulsive disorder: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29287236
UR  - https://www.sciencedirect.com/science/article/pii/S016517811731733X?via%3Dihub
VL  - 261
ER  -
TY  - JOUR
AB  - There is growing interest in the potential role of exercise in the reduction of depressive symptoms. The aim of this meta-analysis was to examine whether exercise reduces depressive symptoms amongst depressed adolescents. The following databases were searched on 30 January 2015: MEDLINE, PsychINFO, SPORTDiscuss and PUBMED. 

Studies were included if they examined exercise interventions amongst adolescents with clinical levels of depressive symptoms, were published in peer-reviewed journals in the English language and contained a control/comparison group. Of 6631 retrieved studies, eight studies were included in the meta-analysis. 

Meta-analysis was conducted using a random effects model due to the high level of heterogeneity identified amongst studies ( I &lt;sup&gt;2&lt;/sup&gt; =65.1, P&lt;.005). The analysis revealed a moderate reduction in depressive symptoms post-intervention (Hedge&#039;s g=-0.61, P=.007). 

This analysis provides preliminary evidence that exercise is effective in reducing symptoms of depression among adolescents with clinical levels of depressive symptoms. The present meta-analysis, however, is limited by the generally low quality of included studies, high level of between-study heterogeneity and restriction of inclusion criteria to published studies. 

Further high-quality trials with depressed adolescents are needed to determine the efficacy of exercise in the reduction of depressive symptoms and the exercise parameters associated with the antidepressant effects of exercise. 

Copyright &copy; 2017 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).
AD  - Radovic, Sara. Centre of Developmental Psychiatry and Psychology, Department of Psychiatry, School of Clinical Sciences,, Melbourne, Victoria, Australia. Gordon, Michael S. Centre of Developmental Psychiatry and Psychology, Department of Psychiatry, School of Clinical Sciences,, Melbourne, Victoria, Australia. Gordon, Michael S. Early in Life Mental Health Services, Monash Health, Melbourne, Victoria, Australia. Melvin, Glenn A. Centre of Developmental Psychiatry and Psychology, Department of Psychiatry, School of Clinical Sciences,, Melbourne, Victoria, Australia.
AN  - 28070942
AU  - Radovic,
AU  - S.
AU  - Gordon,
AU  - M.
AU  - S.
AU  - Melvin,
AU  - G.
AU  - A.
DA  - Jan 10
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jpc.13426
DP  - Ovid Technologies
J2  - J Paediatr Child Health
L1  - internal-pdf://1264559519/Radovic_et_al-2017-Journal_of_Paediatrics_and_.pdf
LA  - English
M3  - Review
N1  - Radovic, Sara Gordon, Michael S Melvin, Glenn A Using Smart Source Parsing Jan
PY  - 2017
SP  - 10
T2  - Journal of Paediatrics and Child Health
TI  - Should we recommend exercise to adolescents with depressive symptoms? A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28070942http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28070942&amp;id=doi:10.1111%2Fjpc.13426&amp;issn=1034-4810&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2017&amp;title=Journal+of+Paediatrics+%26+Child+Health&amp;atitle=Should+we+recommend+exercise+to+adolescents+with+depressive+symptoms%3F+A+meta-analysis.&amp;aulast=Radovic&amp;pid=%3Cauthor%3ERadovic+S%3C%2Fauthor%3E%3CAN%3E28070942%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 10
ER  -
TY  - JOUR
AB  - Children in foster care are at risk for behavioral and emotional problems that require higher levels of care than other children. To meet these needs and reduce placement disruptions, foster parents require effective parenting skills. 

Although a number of training models have been evaluated, the findings on the efficacy of foster parent training (FPT) are mixed. We conducted a meta-analysis of the FPT outcome research from 1984 to 2014 to develop a clearer understanding of the impact of such trainings. 

Fifteen samples (16 studies) were identified that investigated the impact of FPT on self-reported parenting skills and knowledge and child problem behaviors. The mean effect size for child disruptive behavior using a random effects model was small but significant at -.20 (95% confidence interval [CI] = [-.39, -.01], Z = 2.05, p &lt; .05), suggesting that, on average, foster parents who were involved in the trainings reported fewer child behavior problems than parents who did not receive the training. 

The mean effect size for parenting was moderate and significant at .52 (95% CI = [.22, .82], Z = 3.38, p &lt; .05), indicating that, on average, parents in the treatment groups reported higher levels of skills and knowledge following training than did those in the control group. While these results are promising, more research is necessary to investigate the inconsistency in effect sizes across studies.
AD  - Solomon, David T. 1 Center for Children Families and Communities, Central Michigan University, Mt. Pleasant, MI, USA. Niec, Larissa N. 1 Center for Children Families and Communities, Central Michigan University, Mt. Pleasant, MI, USA. Schoonover, Ciera E. 1 Center for Children Families and Communities, Central Michigan University, Mt. Pleasant, MI, USA.
AN  - 27909237
AU  - Solomon,
AU  - D.
AU  - T.
AU  - Niec,
AU  - L.
AU  - N.
AU  - Schoonover,
AU  - C.
AU  - E.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1077559516679514
DP  - Ovid Technologies
J2  - Child Maltreat
L1  - internal-pdf://2623128205/Solomon-2017-The Impact of Foster Parent Train.pdf
LA  - English
N1  - Solomon, David T Niec, Larissa N Schoonover, Ciera E 1077559516679514
PY  - 2017
SP  - 3-13
T2  - Child Maltreatment
TI  - The Impact of Foster Parent Training on Parenting Skills and Child Disruptive Behavior
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27909237http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27909237&amp;id=doi:10.1177%2F1077559516679514&amp;issn=1077-5595&amp;isbn=&amp;volume=22&amp;issue=1&amp;spage=3&amp;pages=3-13&amp;date=2017&amp;title=Child+Maltreatment&amp;atitle=The+Impact+of+Foster+Parent+Training+on+Parenting+Skills+and+Child+Disruptive+Behavior.&amp;aulast=Solomon&amp;pid=%3Cauthor%3ESolomon+DT%3C%2Fauthor%3E%3CAN%3E27909237%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 22
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
This meta-analysis evaluates the efficacy of nonpharmacological treatments for conduct disorder (CD) problems in children and adolescents, based on child, parent and teacher report.

**METHODS: **
PubMed, PsycINFO and EMBASE were searched for peer-reviewed articles published between January 1970 and March 2015. Main inclusion criteria were nonpharmacological treatment, participants younger than 18 years, clinical CD problems/diagnosis, randomized controlled trials and inclusion of at least one CD problem-related outcome. Treatment efficacy is expressed in effect sizes (ESs) calculated for each rater (parent, teacher, self and blinded observer). 

**RESULTS: **
Of 1,549 articles retrieved, 17 (published between June 2004 and January 2014) describing 19 interventions met the inclusion criteria. All studies used psychological treatments; only three studies included a blinded observer to rate CD problems. Most studies were of very poor to fair quality. ESs were significant but small for parent-reported outcomes (0.36, 95% CI = 0.27-0.47), teacher-reported outcomes (0.26, 95% CI = 0.12-0.49) and blinded observer outcomes (0.26, 95% CI = 0.06-0.47), and they were nonsignificant for self-reported outcomes (-0.01, 95% CI = -0.25 to 0.23). Comorbidity, gender, age, number of sessions, duration, intervention type, setting, medication use or dropout percentage did not influence the effect of treatment. 

**CONCLUSIONS: **
Psychological treatments have a small effect in reducing parent-, teacher- and observer-rated CD problems in children and adolescents with clinical CD problems/diagnosis. There is not enough evidence to support one specific psychological treatment over another. Future studies should investigate the influence of participant characteristics (e.g. age of CD onset), use more homogeneous outcome measures and allow better evaluation of study quality. Many reports failed to provide detailed information to allow optimization of psychological treatment strategies. 

Copyright &copy; 2016 Association for Child and Adolescent Mental Health.
AD  - Bakker, M J. Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboudumc, Nijmegen, The Netherlands. Greven, C U. Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboudumc, Nijmegen, The Netherlands. Greven, C U. Karakter Child and Adolescent Psychiatry University Centre Nijmegen, Nijmegen, The Netherlands. Greven, C U. Medical Research Council Social, Genetic &amp; Developmental Psychiatry Centre, Institute of Psychiatry, Psychology &amp; Neuroscience, King&#039;s College London, London, UK. Buitelaar, J K. Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboudumc, Nijmegen, The Netherlands. Buitelaar, J K. Karakter Child and Adolescent Psychiatry University Centre Nijmegen, Nijmegen, The Netherlands. Glennon, J C. Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboudumc, Nijmegen, The Netherlands.
AN  - 27501434
AU  - Bakker,
AU  - M.
AU  - J.
AU  - Greven,
AU  - C.
AU  - U.
AU  - Buitelaar,
AU  - J.
AU  - K.
AU  - Glennon,
AU  - J.
AU  - C.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jcpp.12590
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
L1  - internal-pdf://1429833316/Bakker-2017-Practitioner Review_ Psychological.pdf
LA  - English
M3  - Review
N1  - Bakker, M J Greven, C U Buitelaar, J K Glennon, J C
PY  - 2017
SP  - 4-18
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Practitioner Review: Psychological treatments for children and adolescents with conduct disorder problems - a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27501434http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27501434&amp;id=doi:10.1111%2Fjcpp.12590&amp;issn=0021-9630&amp;isbn=&amp;volume=58&amp;issue=1&amp;spage=4&amp;pages=4-18&amp;date=2017&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Practitioner+Review%3A+Psychological+treatments+for+children+and+adolescents+with+conduct+disorder+problems+-+a+systematic+review+and+meta-analysis.&amp;aulast=Bakker&amp;pid=%3Cauthor%3EBakker+MJ%3C%2Fauthor%3E%3CAN%3E27501434%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1111/jcpp.12590/asset/jcpp12590.pdf?v=1&amp;t=j02cwg5e&amp;s=9fef949039174649db77f5d2ae98951a2729f0a3
VL  - 58
ER  -
TY  - JOUR
AB  - **Background: **
Online and mobile telephone applications (&#039;apps&#039;) have the potential to improve the scalability of effective interventions for suicidal ideation and self-harm. The aim of this review was therefore to investigate the effectiveness of digital interventions for the self-management of suicidal ideation or self-harm. 

**Methods: **
Seven databases (Applied Science &amp; Technology; CENTRAL; CRESP; Embase; Global Health; PsycARTICLES; PsycINFO; Medline) were searched to 31 March, 2017. Studies that examined the effectiveness of digital interventions for suicidal ideation and/or self-harm, or which reported outcome data for suicidal ideation and/or self-harm, within a randomised controlled trial (RCT), pseudo-RCT, or observational pre-test/post-test design were included in the review. 

**Results:**
Fourteen non-overlapping studies were included, reporting data from a total of 3,356 participants. Overall, digital interventions were associated with reductions for suicidal ideation scores at post-intervention. There was no evidence of a treatment effect for self-harm or attempted suicide. 

**Conclusions: **
Most studies were biased in relation to at least one aspect of study design, and particularly the domains of participant, clinical personnel, and outcome assessor blinding. Performance and detection bias therefore cannot be ruled out. Digital interventions for suicidal ideation and self-harm may be more effective than waitlist control. It is unclear whether these reductions would be clinically meaningful at present. Further evidence, particularly with regards to the potential mechanisms of action of these interventions, as well as safety, is required before these interventions could recommended.
AN  - WOS:000407977400004
AU  - Witt,
AU  - K.
AU  - Spittal,
AU  - M.
AU  - J.
AU  - Carter,
AU  - G.
AU  - Pirkis,
AU  - J.
AU  - Hetrick,
AU  - S.
AU  - Currier,
AU  - D.
AU  - Robinson,
AU  - J.
AU  - Milner,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/s12888-017-1458-0
L1  - internal-pdf://1845398324/Witt-2017-Effectiveness of online and mobile t.pdf
PY  - 2017
SP  - 18
TI  - Effectiveness of online and mobile telephone applications (&#039;apps&#039;) for the self-management of suicidal ideation and self-harm: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000407977400004
VL  - 17
ER  -
TY  - JOUR
AB  - **Background:**
Unintended repeat conceptions can result in emotional, psychological and educational harm to young women, often with enduring implications for their life chances. This study aimed to identify which young women are at the greatest risk of repeat unintended pregnancies; which interventions are effective and cost-effective; and what are the barriers to and facilitators for the uptake of these interventions. 

**Methods: **
We conducted a mixed-methods systematic review which included meta-analysis, framework synthesis and application of realist principles, with stakeholder input and service user feedback to address this. We searched 20 electronic databases, including MEDLINE, Excerpta Medica database, Applied Social Sciences Index and Abstracts and Research Papers in Economics, to cover a broad range of health, social science, health economics and grey literature sources. Searches were conducted between May 2013 and June 2014 and updated in August 2015. 

**Results: **
Twelve randomised controlled trials (RCTs), two quasi-RCTs, 10 qualitative studies and 53 other quantitative studies were identified. The RCTs evaluated psychosocial interventions and an emergency contraception programme. The primary outcome was repeat conception rate: the event rate was 132 of 308 (43%) in the intervention group versus 140 of 289 (48%) for the control group, with a non-significant risk ratio (RR) of 0.92 [95% confidence interval (CI) 0.78-1.08]. Four studies reported subsequent birth rates: 29 of 237 (12%) events for the intervention arm versus 46 out of 224 (21%) for the control arm, with an RR of 0.60 (95% CI 0.39-0.93). Many repeat conceptions occurred in the context of poverty, low expectations and aspirations and negligible opportunities. Qualitative and realist evidence highlighted the importance of context, motivation, future planning and giving young women a central and active role in the development of new interventions. 

**Conclusions: **
Little or no evidence for the effectiveness or cost-effectiveness of any of the interventions to reduce repeat pregnancy in young women was found. Qualitative and realist evidence helped to explain gaps in intervention design that should be addressed. More theory-based, rigorously evaluated programmes need to be developed to reduce unintended repeat pregnancy in young women. 

Trial registration: PROSPERO, CRD42012003168. Cochrane registration number: i=fertility/0068 
Copyright &copy; 2017 The Author(s).
AN  - 617759799
AU  - Aslam,
AU  - R.
AU  - W.
AU  - Hendry,
AU  - M.
AU  - Booth,
AU  - A.
AU  - Carter,
AU  - B.
AU  - Charles,
AU  - J.
AU  - M.
AU  - Craine,
AU  - N.
AU  - Edwards,
AU  - R.
AU  - T.
AU  - Noyes,
AU  - J.
AU  - Ntambwe,
AU  - L.
AU  - I.
AU  - Pasterfield,
AU  - D.
AU  - Rycroft-Malone,
AU  - J.
AU  - Williams,
AU  - N.
AU  - Whitaker,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s12916-017-0904-7
L1  - internal-pdf://0923888766/Aslam-2017-Intervention Now to Eliminate Repea.pdf
PY  - 2017
TI  - Intervention Now to Eliminate Repeat Unintended Pregnancy in Teenagers (INTERUPT): A systematic review of intervention effectiveness and cost-effectiveness, and qualitative and realist synthesis of implementation factors and user engagement
UR  - http://www.biomedcentral.com/bmcmed/
VL  - 15 (1) (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The majority of survivors of mass violence live in low- and middle-income countries (LMICs). AIMS: To synthesise empirical findings for psychological interventions for children and adolescents with post-traumatic stress disorder (PTSD) and/or depression in LMICs affected by mass violence. 

**METHOD: **
Randomised controlled trials with children and adolescents with symptoms of PTSD and/or depression in LMICs were identified. Overall, 21 812 records were found through July 2016 in the Medline, PsycINFO and PILOTS databases; 21 met the inclusion criteria and were reviewed according to recommended guidelines. 

**RESULTS: **
Twenty-one studies were included. Active treatments for PTSD yielded large pre-treatment to post-treatment changes (g = 1.15) and a medium controlled effect size (g = 0.57). Effect sizes were similar at follow-up. Active treatments for depression produced small to medium effect sizes. Finally, after adjustment for publication bias, the imputed uncontrolled and controlled effect sizes for PTSD were medium and small respectively.

**CONCLUSIONS:**
Psychological interventions may be effective in treating paediatric PTSD in LMICs. It appears that more targeted approaches are needed for depressive responses. 

Copyright &copy; The Royal College of Psychiatrists 2017.
AD  - Morina, Nexhmedin. Nexhmedin Morina, PhD, Department of Psychology, University of Munster, Munster, Germany; Mina Malek, MS, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands; Angela Nickerson, PhD, Richard A. Bryant, PhD, School of Psychology, University of New South Wales, NSW, Sydney, Australia morina@uni-muenster.de. Malek, Mina. Nexhmedin Morina, PhD, Department of Psychology, University of Munster, Munster, Germany; Mina Malek, MS, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands; Angela Nickerson, PhD, Richard A. Bryant, PhD, School of Psychology, University of New South Wales, NSW, Sydney, Australia. Nickerson, Angela. Nexhmedin Morina, PhD, Department of Psychology, University of Munster, Munster, Germany; Mina Malek, MS, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands; Angela Nickerson, PhD, Richard A. Bryant, PhD, School of Psychology, University of New South Wales, NSW, Sydney, Australia. Bryant, Richard A. Nexhmedin Morina, PhD, Department of Psychology, University of Munster, Munster, Germany; Mina Malek, MS, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands; Angela Nickerson, PhD, Richard A. Bryant, PhD, School of Psychology, University of New South Wales, NSW, Sydney, Australia.
AN  - 28153930
AU  - Morina,
AU  - N.
AU  - Malek,
AU  - M.
AU  - Nickerson,
AU  - A.
AU  - Bryant,
AU  - R.
AU  - A.
DA  - Feb 02
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1192/bjp.bp.115.180265
DP  - Ovid Technologies
J2  - Br J Psychiatry
L1  - internal-pdf://1143112061/Morina_2017.pdf
LA  - English
M3  - Review
N1  - Morina, Nexhmedin Malek, Mina Nickerson, Angela Bryant, Richard A Using Smart Source Parsing Feb bjp.bp.115.180265
PY  - 2017
SP  - 02
T2  - British Journal of Psychiatry
TI  - Psychological interventions for post-traumatic stress disorder and depression in young survivors of mass violence in low- and middle-income countries: meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28153930http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28153930&amp;id=doi:10.1192%2Fbjp.bp.115.180265&amp;issn=0007-1250&amp;isbn=&amp;volume=&amp;issue=&amp;spage=bjp&amp;pages=&amp;date=2017&amp;title=British+Journal+of+Psychiatry&amp;atitle=Psychological+interventions+for+post-traumatic+stress+disorder+and+depression+in+young+survivors+of+mass+violence+in+low-+and+middle-income+countries%3A+meta-analysis.&amp;aulast=Morina&amp;pid=%3Cauthor%3EMorina+N%3C%2Fauthor%3E%3CAN%3E28153930%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 02
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
To study in more depth the relationship between type, dose, or duration of methylphenidate offered to children and adolescents with attention deficit hyperactivity disorder and their risks of gastrointestinal adverse events based on our Cochrane systematic review. 

**METHODS AND FINDINGS: **
We use data from our review including 185 randomised clinical trials. Randomised parallel-group trials and cross-over trials reporting gastrointestinal adverse events associated with methylphenidate were included. Data were extracted and quality assessed according to Cochrane guidelines. Data were summarised as risk ratios (RR) with 95% confidence intervals (CI) using the inverse variance method. Bias risks were assessed according to domains. Trial Sequential Analysis (TSA) was used to control random errors. Eighteen parallel group trials and 43 cross-over trials reported gastrointestinal adverse events. 

All trials were at high risk of bias. In parallel group trials, methylphenidate decreased appetite (RR 3.66, 95% CI 2.56 to 5.23) and weight (RR 3.89, 95% CI 1.43 to 10.59). In cross-over trials, methylphenidate increased abdominal pain (RR 1.61, 95% CI 1.27 to 2.04). We found no significant differences in the risk according to type, dose, or duration of administration. The required information size was achieved in three out of four outcomes. 

**CONCLUSION: **
Methylphenidate increases the risks of decreased appetite, weight loss, and abdominal pain in children and adolescents with attention deficit hyperactivity disorder. No differences in the risks of gastrointestinal adverse events according to type, dose, or duration of administration were found.
AN  - 28617801
AU  - Holmskov,
AU  - M.
AU  - Storebo,
AU  - O.
AU  - J.
AU  - Moreira-Maia,
AU  - C.
AU  - R.
AU  - Ramstad,
AU  - E.
AU  - Magnusson,
AU  - F.
AU  - L.
AU  - Krogh,
AU  - H.
AU  - B.
AU  - Groth,
AU  - C.
AU  - Gillies,
AU  - D.
AU  - Zwi,
AU  - M.
AU  - Skoog,
AU  - M.
AU  - Gluud,
AU  - C.
AU  - Simonsen,
AU  - E.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1371/journal.pone.0178187
L1  - internal-pdf://3571391050/Holmskov-2017-Gastrointestinal adverse events.pdf
PY  - 2017
SP  - e0178187
T2  - PLoS ONE [Electronic Resource]
TI  - Gastrointestinal adverse events during methylphenidate treatment of children and adolescents with attention deficit hyperactivity disorder: A systematic review with meta-analysis and Trial Sequential Analysis of randomised clinical trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=28617801
UR  - https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0178187&amp;type=printable
VL  - 12
ER  -
TY  - JOUR
AB  - **Background: **
There has an increasing number of published trials on psychosocial intervention programmes for pre-school children with autism spectrum disorder (ASD). To achieve better quality of unbiased evidence for the effectiveness of ASD interventions, it is necessary to conduct a comprehensive review that covers studies with adequate quality standards, such as randomised controlled trials (RCTs), and different types of intervention In this study, we categorize interventions for ASD as behavioural, social-communication focused, and multimodal developmental based on Howlin&#039;s classification of early interventions for children with ASD. The aim of this study was to compare these three models and investigate the strengths and weaknesses of each type of intervention and to identify the approaches that contribute to a successful outcome for children with autism. 

**Methods: **
We performed a systematic review and meta-analysis. We included RCTs targeting children with ASD 6 years old or younger. A random effects model was used to present the effect estimate for the outcomes. This study also performed combined meta-analyses of all the three models to investigate the overall effectiveness of the intervention programmes. 

**Results: **
32 randomized controlled studies were found to be eligible for inclusion. The synthesized data included 594 children from 14 RCTs. There was no statistically significant difference in the effects on autism general symptoms between the social-communication-focused model and the multimodal developmental model (p = 0.83). The results suggest that there is evidence of an effect on &#039;reciprocity of social interaction towards others&#039; (standard mean difference [95% confidential interval] = 0.53[0.29,0.78], p&lt;0.01) and &#039;parental synchrony&#039; (SMD = 0.99[0.70,1.29], p&lt;0.01). 

**Conclusion: **
The small number of studies included in the present study limited the ability to make inferences when comparing the three models and investigating the strengths and weaknesses of each type of intervention with respect to important outcomes. Since the outcome of &#039;reciprocity of social interaction towards others&#039; could be a dependent variable that might be context-bound to interactions with the child&#039;s parent, we cannot conclude the interventions for pre-school children with ASD have significant effects on a generalized skill to engage in reciprocal interactions with others. However, the outcomes of &#039;reciprocity of social interaction towards others&#039; and &#039;parental synchrony&#039; may be promising targets for interventions involving pre-school children with ASD. 

**Trial registration: **
Prospero CRD42011001349. 

Copyright &copy; 2017 Tachibana et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AN  - 619533641
AU  - Tachibana,
AU  - Y.
AU  - Miyazaki,
AU  - C.
AU  - Ota,
AU  - E.
AU  - Mori,
AU  - R.
AU  - Hwang,
AU  - Y.
AU  - Kobayashi,
AU  - E.
AU  - Terasaka,
AU  - A.
AU  - Tang,
AU  - J.
AU  - Kamio,
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0186502
L1  - internal-pdf://2609560609/tachibana.pdf
PY  - 2017
T2  - PLoS ONE
TI  - A systematic review and meta-analysis of comprehensive interventions for pre-school children with autism spectrum disorder (ASD)
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0186502&amp;type=printable
VL  - 12 (12) (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Child disruptive behavioural problems are a large and costly public health problem. The Incredible Years (IY) parenting programme has been disseminated across the UK to prevent this problem and shown to be effective in several trials. It is vital for policy to know for which families IY is most effective, to be sure that it helps reduce, rather than widen, socioeconomic inequalities. Individual trials lack power and generalisability to examine differential effects; conventional meta-analysis lacks information about within-trial variability in effects.

**OBJECTIVES: **
To overcome these limitations by pooling individual-level data from the IY parenting trials in Europe to examine to what extent it benefits socially disadvantaged families. Secondary objectives examine (1) additional moderators of effects on child behaviour, (2) wider health benefits and potential harms and (3) costs, cost-effectiveness and potential long-term savings.

**DESIGN: **
Individual participant data meta-analysis of 14 randomised trials of the IY parenting intervention.

**SETTINGS: **
UK (eight trials), the Netherlands, Ireland, Norway, Sweden and Portugal.

**PARTICIPANTS: **
Data were from 1799 families, with children aged 2-10 years (mean 5.1 years; 63% boys).

**INTERVENTIONS: **
IY Basic parenting programme.

**MAIN OUTCOME MEASURES: **
Primary outcome was disruptive child behaviour, determined by the Eyberg Child Behavior Inventory Intensity scale (ECBI-I). Secondary outcomes included self-reported parenting practices, parenting stress, mental health, children&#039;s attention deficit hyperactivity disorder (ADHD) and emotional symptoms.

**RESULTS: **
There were no differential effects of IY on disruptive behaviour in families with different levels of social/socioeconomic disadvantage or differential effects for ethnic minority families, families with different parenting styles, or for children with comorbid ADHD or emotional problems or of different ages. Some moderators were found: intervention effects were strongest in children with more severe baseline disruptive behaviour, in boys, and in children with parents who were more depressed. Wider health benefits included reduced child ADHD symptoms, greater parental use of praise, and reduced harsh and inconsistent discipline. The intervention did not improve parental depression, stress, self-efficacy or children&#039;s emotional problems. Economic data were available for five UK and Ireland trials (maximum n=608). The average cost per person of the IY intervention was 2414. The probability that the IY intervention is considered cost-effective is 99% at a willingness to pay of 145 per 1-point improvement on the ECBI-I. Estimated longer-term savings over 20 years range from 1000 to 8400 per child, probably offsetting the cost of the intervention.

**LIMITATIONS: **
Limitations include a focus on one parenting programme; the need to make assumptions in harmonising data; and the fact that data addressed equalities in the effectiveness of, not access to, the intervention.

**CONCLUSIONS:**
There is no evidence that the benefits of the IY parenting intervention are reduced in disadvantaged or minority families; benefits are greater in the most distressed families, including parents who are depressed. Thus, the intervention is unlikely to widen socioeconomic inequalities in disruptive behaviour and may have effects in narrowing inequalities due to parent depression. It was as likely to be effective for older as for younger children. It has wider benefits for ADHD and parenting and is likely to be considered to be cost-effective. Researchers/funders should encourage data sharing to test equity and other moderator questions for other interventions; further research is needed on enhancing equality of access to interventions.

**FUNDING: **
The National Institute for Health Research Public Health Research programme.
AD  - Gardner, Frances. Department of Social Policy and Intervention, Centre for Evidence-based Intervention, University of Oxford, Oxford, UKLeijten, Patty. Department of Social Policy and Intervention, Centre for Evidence-based Intervention, University of Oxford, Oxford, UKMann, Joanna. Department of Social Policy and Intervention, Centre for Evidence-based Intervention, University of Oxford, Oxford, UKLandau, Sabine. Institute of Psychiatry, Psychology and Neuroscience, King&#039;s College London, London, UKHarris, Victoria. Institute of Psychiatry, Psychology and Neuroscience, King&#039;s College London, London, UKBeecham, Jennifer. Personal Social Services Research Unit, London School of Economics and Political Science, London, UKBonin, Eva-Maria. Personal Social Services Research Unit, London School of Economics and Political Science, London, UKHutchings, Judy. School of Psychology, Bangor University, Bangor, UKScott, Stephen. Institute of Psychiatry, Psychology and Neuroscience, King&#039;s College London, London, UK
AN  - 29227603
AU  - Gardner,
AU  - F.
AU  - Leijten,
AU  - P.
AU  - Mann,
AU  - J.
AU  - Landau,
AU  - S.
AU  - Harris,
AU  - V.
AU  - Beecham,
AU  - J.
AU  - Bonin,
AU  - E.
AU  - M.
AU  - Hutchings,
AU  - J.
AU  - Scott,
AU  - S.
DA  - 12
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3310/phr05100
DP  - Ovid Technologies
J2  - NIHR Journals Library
L1  - internal-pdf://0467040858/gardner2017.pdf
LA  - English
M3  - Review
N1  - Gardner, FrancesLeijten, PattyMann, JoannaLandau, SabineHarris, VictoriaBeecham, JenniferBonin, Eva-MariaHutchings, JudyScott, StephenUsing Smart Source Parsing
PY  - 2017
SP  - 12
T2  - NIHR Journals Library. Public Health Research
TI  - Could scale-up of parenting programmes improve child disruptive behaviour and reduce social inequalities? Using individual participant data meta-analysis to establish for whom programmes are effective and cost-effective
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29227603
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:29227603&amp;id=doi:10.3310%2Fphr05100&amp;issn=&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2017&amp;title=%3D%3D%3D&amp;atitle=&amp;aulast=Gardner&amp;pid=%3Cauthor%3EGardner+F%3C%2Fauthor%3E%3CAN%3E29227603%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 12
ER  -
TY  - JOUR
AB  - Parent training (PT) has emerged as a promising treatment for disruptive behavior in children with autism spectrum disorder (ASD). 

This review summarizes the essential elements of PT for disruptive behavior in children with ASD and evaluates the available evidence for PT using both descriptive and meta-analytic procedures. We searched Medline, PsycINFO, and PubMed databases (1980-2016) in peer-reviewed journals for randomized controlled trials (RCTs) of PT for disruptive behavior in children with ASD. 

The systematic search of 2023 publications yielded eight RCTs involving a total of 653 participants. We calculated effect sizes using either raw post-treatment means and standard deviations for each treatment group (PT and control) or group mean differences with associated 95% confidence intervals (CIs). Differences in post-treatment means were converted to a standardized difference in means (SMD) for each primary outcome. 

Results support the efficacy of PT for disruptive behavior in children with ASD, with a SMD of -0.59 [95% CI (-0.88, -0.30); p &lt; 0.001]. Across these eight studies, there was significant heterogeneity in the effect of PT on disruptive behavior. This variability is likely due to differences in sample size, number of treatment sessions, study duration, and control condition employed. 

Current findings provide solid support for the efficacy of PT for disruptive behavior in children with ASD. Future studies should focus on effectiveness trials to promote wider implementation of PT in clinical settings.
AN  - WOS:000413686500002
AU  - Postorino,
AU  - V.
AU  - Sharp,
AU  - W.
AU  - G.
AU  - McCracken,
AU  - C.
AU  - E.
AU  - Bearss,
AU  - K.
AU  - Burrell,
AU  - T.
AU  - L.
AU  - Evans,
AU  - A.
AU  - N.
AU  - Scahill,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10567-017-0237-2
L1  - internal-pdf://3682004445/Postorino-2017-A Systematic Review and Meta-an.pdf
PY  - 2017
SP  - 391-402
T2  - Clinical Child and Family Psychology Review
TI  - A Systematic Review and Meta-analysis of Parent Training for Disruptive Behavior in Children with Autism Spectrum Disorder
UR  - &lt;Go to ISI&gt;://WOS:000413686500002
VL  - 20
ER  -
TY  - JOUR
AB  - We aimed to provide an overview of psychotherapy in young anxious children (mean age, &lt;7 years). Seven electronic databases, including PubMed, EMBASE, Cochrane, Web of Science, PsycINFO, CINAHL, and ProQuest Dissertations, were searched. 

Randomized controlled trials that compared psychotherapies with control conditions were included. Efficacy (score change on an anxiety rating scale and rate of being freed from anxiety) and acceptability (discontinuations due to any event) were evaluated. Six of the total seven studies included in our study adopted cognitive behavioral therapy (CBT), with only one adopting behavior therapy (BT). 

Psychotherapy effectively reduced anxiety symptoms (standardized mean difference = -0.83; 95% confidence interval [CI], -1.08 to -0.57), and its rate of freeing patients from anxiety was high (risk ratio [RR] = 0.30; 95% CI, 0.19 to 0.47). 

No remarkable difference for acceptability was found between the two therapy types (RR = 0.54; 95% CI, 0.25 to 1.18). Psychotherapy, both CBT and BT, benefits young anxious children.
AN  - 29064948
AU  - Zhang,
AU  - H.
AU  - Zhang,
AU  - Y.
AU  - Yang,
AU  - L.
AU  - Yuan,
AU  - S.
AU  - Zhou,
AU  - X.
AU  - Pu,
AU  - J.
AU  - Liu,
AU  - L.
AU  - Jiang,
AU  - X.
AU  - Xie,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/NMD.0000000000000749
L1  - internal-pdf://1588561601/Zhang-2017-Efficacy and Acceptability of Psych.pdf
PY  - 2017
SP  - 23
TI  - Efficacy and Acceptability of Psychotherapy for Anxious Young Children: A Meta-analysis of Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29064948
VL  - 23
ER  -
TY  - JOUR
AB  - The use of mobile technology is ubiquitous in modern society and is rapidly increasing in novel use. 

The use of mobile devices and software applications (&quot;apps&quot;) as augmentative and alternative communication (AAC) is rapidly expanding in the community, and this is also reflected in the research literature. 

This article reports the social-communication outcome results of a meta-analysis of single-case experimental research on the use of high-tech AAC, including mobile devices, by individuals with intellectual and developmental disabilities, including autism spectrum disorder. 

Following inclusion determination, and excluding studies with poor design quality, raw data from 24 publications were extracted and included 89 A-B phase contrasts. Tau-U nonparametric, non-overlap effect size was used to aggregate the results across all studies for an omnibus and moderator analyses. 

Kendall&#039;s S was calculated for confidence intervals, p-values, and standard error. The omnibus analysis indicated overall low to moderate positive effects on social-communication outcomes for high-tech AAC use by individuals with intellectual and developmental disabilities.
AN  - WOS:000415802400004
AU  - Ganz,
AU  - J.
AU  - B.
AU  - Morin,
AU  - K.
AU  - L.
AU  - Foster,
AU  - M.
AU  - J.
AU  - Vannest,
AU  - K.
AU  - J.
AU  - Tosun,
AU  - D.
AU  - G.
AU  - Gregori,
AU  - E.
AU  - V.
AU  - Gerow,
AU  - S.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/07434618.2017.1373855
L1  - internal-pdf://3803356056/Ganz-2017-High-technology augmentative and alt.pdf
PY  - 2017
SP  - 224-238
T2  - Augmentative and Alternative Communication
TI  - High-technology augmentative and alternative communication for individuals with intellectual and developmental disabilities and complex communication needs: a meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000415802400004
UR  - https://www.tandfonline.com/doi/pdf/10.1080/07434618.2017.1373855?needAccess=true
VL  - 33
ER  -
TY  - JOUR
AB  - **Background:** 
Autism spectrum disorders (ASDs) are characterised by impairments in communication and reciprocal social interaction. These impairments can impact on relationships with family members, augment stress and frustration, and contribute to behaviours that can be described as challenging. Family members of individuals with ASD can experience high rates of carer stress and burden, and poor parental efficacy. While there is evidence to suggest that individuals with ASD and family members derive benefit from psychological interventions designed to reduce stress and mental health morbidity, and enhance coping, most studies to date have targeted the needs of either individuals with ASD, or family members. We wanted to examine whether family (systemic) therapy, aimed at enhancing communication, relationships or coping, is effective for individuals with ASD and their wider family network.

**Objectives:** 
To evaluate the clinical effectiveness and acceptability of family therapy as a treatment to enhance communication or coping for individuals with ASD and their family members. If possible, we will also seek to establish the economic costs associated with family therapy for this clinical population.Search methods: On 16 January 2017 we searched CENTRAL, MEDLINE, Embase, 10 other databases and three trials registers. We also handsearched reference lists of existing systematic reviews and contacted study authors in the field.

**Selection criteria:** 
Randomised controlled trials (RCTs) and quasi-RCTs investigating the effectiveness of family therapy for young people or adults with ASD or family members, or both, delivered via any modality and for an unspecified duration, compared with either standard care, a wait-list control, or an active intervention such as an alternative type of psychological therapy.

**Data collection and analysis:** 
Two authors independently screened each title and abstract and all full-text reports retrieved. To enhance rigour, 25% of these were independently screened by a third author.

**Main results:** 
The search yielded 4809 records. Of these, we retrieved 37 full-text reports for further scrutiny, which we subsequently excluded as they did not meet the review inclusion criteria, and identified one study awaiting classification.

**Authors&#039; conclusions:**
Few studies have examined the effectiveness of family therapy for ASD, and none of these are RCTs. Further research studies employing methodologically robust trial designs are needed to establish whether family therapy interventions are clinically beneficial for enhancing communication, strengthening relationships, augmenting coping and reducing mental health morbidity for individuals with ASD and family members.
AU  - Spain,
AU  - D.
AU  - Sin,
AU  - J.
AU  - Paliokosta,
AU  - E.
AU  - Furuta,
AU  - M.
AU  - Prunty,
AU  - J.
AU  - E.
AU  - Chalder,
AU  - T.
AU  - Murphy,
AU  - D.
AU  - G.
AU  - Happ&eacute;,
AU  - F.
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD011894.pub2
KW  - : CD011894
PY  - 2017
T2  - Cochrane Database of Systematic Reviews
TI  - Family therapy for autism spectrum disorders
ER  -
TY  - JOUR
AB  - **Objectives **
Compare the safety of antiepileptic drugs (AEDs) on neurodevelopment of infants/children exposed in utero or during breast feeding. 

**Design and setting **
Systematic review and Bayesian random-effects network meta-analysis (NMA). MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials were searched until 27 April 2017. Screening, data abstraction and quality appraisal were completed in duplicate by independent reviewers. Participants 29 cohort studies including 5100 infants/children. 

**Interventions **
Monotherapy and polytherapy AEDs including first-generation (carbamazepine, clobazam, clonazepam, ethosuximide, phenobarbital, phenytoin, primidone, valproate) and newer-generation (gabapentin, lamotrigine, levetiracetam, oxcarbazepine, topiramate, vigabatrin) AEDs. Epileptic women who did not receive AEDs during pregnancy or breast feeding served as the control group. 

**Primary and secondary outcome measures **
Cognitive developmental delay and autism/dyspraxia were primary outcomes. Attention-deficit hyperactivity disorder, language delay, neonatal seizures, psychomotor developmental delay and social impairment were secondary outcomes. 

**Results **
The NMA on cognitive developmental delay (11 cohort studies, 933 children, 18 treatments) suggested that among all AEDs only valproate was statistically significantly associated with more children experiencing cognitive developmental delay compared with control (OR=7.40, 95% credible interval (CrI) 3.00 to 18.46). The NMA on autism (5 cohort studies, 2551 children, 12 treatments) suggested that oxcarbazepine (OR 13.51, CrI 1.28 to 221.40), valproate (OR 17.29, 95% CrI 2.40 to 217.60), lamotrigine (OR 8.88, CrI 1.28 to 112.00) and lamotrigine+valproate (OR 132.70, CrI 7.41 to 3851.00) were associated with significantly greater odds of developing autism compared with control. The NMA on psychomotor developmental delay (11 cohort studies, 1145 children, 18 treatments) found that valproate (OR 4.16, CrI 2.04 to 8.75) and carbamazepine+phenobarbital+valproate (OR 19.12, CrI 1.49 to 337.50) were associated with significantly greater odds of psychomotor delay compared with control. 

**Conclusions **
Valproate alone or combined with another AED is associated with the greatest odds of adverse neurodevelopmental outcomes compared with control. Oxcarbazepine and lamotrigine were associated with increased occurrence of autism. Counselling is advised for women considering pregnancy to tailor the safest regimen. Trial registration number PROSPERO database (CRD42014008925). 

Copyright &copy; 2017 Article author(s) (or their employer(s) unless otherwise stated in the text of the article). All rights reserved. No commercial use is permitted unless otherwise expressly granted.
AN  - 617415543
AU  - Veroniki,
AU  - A.
AU  - A.
AU  - Rios,
AU  - P.
AU  - Cogo,
AU  - E.
AU  - Straus,
AU  - S.
AU  - E.
AU  - Finkelstein,
AU  - Y.
AU  - Kealey,
AU  - R.
AU  - Reynen,
AU  - E.
AU  - Soobiah,
AU  - C.
AU  - Thavorn,
AU  - K.
AU  - Hutton,
AU  - B.
AU  - Hemmelgarn,
AU  - B.
AU  - R.
AU  - Yazdi,
AU  - F.
AU  - D&#039;Souza,
AU  - J.
AU  - Macdonald,
AU  - H.
AU  - Tricco,
AU  - A.
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmjopen-2017-017248
L1  - internal-pdf://3254275730/Veroniki-2017-Comparative safety of antiepilep.pdf
PY  - 2017
TI  - Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: A systematic review and network meta-analysis
UR  - http://bmjopen.bmj.com/content/early/by/section
VL  - 7 (7) (no pagination)
ER  -
TY  - JOUR
AB  - The popularity of mindfulness-based interventions (MBIs) is growing rapidly in schools. Decisions regarding the use of these interventions must be based on empirical evidence. 

There is robust evidence for the use of MBIs with adults, but research on MBIs with youth is nascent. The purpose of this meta-analytic review was to add to the literature by synthesizing single-case research on MBIs with children and adolescents. Specifically, the effect of MBIs on youths&#039; disruptive behavior was examined in 10 studies published between 2006 and 2014. 

Results indicated that, on average, MBIs had a medium effect on disruptive behavior during treatment, g = 1.04, 95% confidence interval (CI) [0.30-1.78]; TauU = 0.59, 95% CI [0.40-0.77]. The average effect of MBIs during maintenance phases was larger, g = 1.41, 95% CI [0.55-2.28]; TauU = 0.71, 95% CI [0.59-0.83]. 

Potential moderators of intervention effects were also explored. Implications for future research and practice regarding MBIs with youth and in schools are discussed.
AD  - [Klingbeil, David A.; Willenbrink, Jessica B.; Copek, Rebecca A.; Chan, Kai Tai] Univ Wisconsin Milwaukee, Milwaukee, WI USA. [Fischer, Aaron J.] Univ Utah, Salt Lake City, UT 84112 USA. [Renshaw, Tyler L.] Louisiana State Univ, Baton Rouge, LA 70803 USA. Klingbeil, DA (reprint author), Univ Wisconsin, Dept Educ Psychol, POB 413, Milwaukee, WI 53201 USA. davidak5@uwm.edu
AN  - WOS:000390596700005
AU  - Klingbeil,
AU  - D.
AU  - A.
AU  - Fischer,
AU  - A.
AU  - J.
AU  - Renshaw,
AU  - T.
AU  - L.
AU  - Bloomfield,
AU  - B.
AU  - S.
AU  - Polakoff,
AU  - B.
AU  - Willenbrink,
AU  - J.
AU  - B.
AU  - Copek,
AU  - R.
AU  - A.
AU  - Chan,
AU  - K.
AU  - T.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/pits.21982
J2  - Psychol. Schools
KW  - parenting decreases aggression
KW  - school settings
KW  - effect size
KW  - children
KW  - students
KW  - designs
KW  - adolescents
KW  - disorder
KW  - youth
KW  - prevention
KW  - Psychology
L1  - internal-pdf://4292158772/Klingbeil-2017-EFFECTS OF MINDFULNESS-BASED IN.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: EF8RJ Times Cited: 0 Cited Reference Count: 72 Klingbeil, David A. Fischer, Aaron J. Renshaw, Tyler L. Bloomfield, Bradley S. Polakoff, Ben Willenbrink, Jessica B. Copek, Rebecca A. Chan, Kai Tai 0 7 Wiley-blackwell Hoboken 1520-6807
PY  - 2017
SP  - 70-87
T2  - Psychology in the Schools
TI  - Effects of mindfulness-based interventions on disruptive behavior: A meta-analysis of single-case research
UR  - &lt;Go to ISI&gt;://WOS:000390596700005
UR  - http://onlinelibrary.wiley.com/store/10.1002/pits.21982/asset/pits21982.pdf?v=1&amp;t=j02ex8x8&amp;s=ede17cfbb59de9b6848fd072007427df46ee9166
VL  - 54
ER  -
TY  - JOUR
AB  - The relative safety of antidepressants during pregnancy has received substantial attention, but most syntheses fail to account for mental illness effects. 

We aimed to evaluate the literature comparing low birth weight (LBW) and neurodevelopmental and neurobehavioural outcomes for children whose mothers took antidepressants in pregnancy compared to those whose mothers had common mental disorders, or symptoms, but who did not take antidepressants during pregnancy. 

A systematic review was conducted searching PubMed, MEDLINE, PsycINFO and Embase in January 2015. A modified version of the Newcastle Ottawa Scale was used to assess study quality. Eleven cohort studies were included: four reporting a LBW outcome (all with higher risk of bias) and seven reporting a neurodevelopmental outcome (five with higher risk of bias). 

We found only limited evidence of gestational age-adjusted LBW in exposed children in two studies which had a higher risk of bias and did not control for depressive symptom severity. Only five (7.5%) neurodevelopmental outcomes and one (12.5%) neurobehavioural outcome showed evidence of a statistically significant effect, three out of four were from studies with a higher risk of bias. 

There is little robust evidence indicating a detrimental effect of antidepressant use during pregnancy on LBW and neurodevelopmental and neurobehavioural outcomes. More rigorous study designs are needed. 

Copyright &copy; 2017 The Author(s)
AN  - 618784960
AU  - Prady,
AU  - S.
AU  - L.
AU  - Hanlon,
AU  - I.
AU  - Fraser,
AU  - L.
AU  - K.
AU  - Mikocka-Walus,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00737-017-0780-3
L1  - internal-pdf://0238189420/Prady-2017-A systematic review of maternal ant.pdf
PY  - 2017
SP  - 1-14
TI  - A systematic review of maternal antidepressant use in pregnancy and short- and long-term offspring&#039;s outcomes
UR  - http://www.springer.co.at/springer.py?Page=40&amp;Key=545&amp;cat=11&amp;id_journal=40
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To summarize risks related to (1) illness and (2) second-generation antipsychotic (SGA) treatment in pregnant women and their offspring. Concerning illness-related risks, we focused on bipolar disorder and schizophrenia, psychiatric disorders for which SGAs are preferentially prescribed.

**DATA SOURCES: **
PubMed, Ovid, Scopus, PsycINFO, and Cochrane Library were searched from the date of the first available article to October 2015 using the following key terms: pregnancy OR gestation OR bipolar disorder OR schizophrenia. We also included cross-references from identified articles.

**STUDY SELECTION: **
We included 49 English-language articles regarding illness-related and SGA-related risks in bipolar disorder and schizophrenia. First, searches were done for epidemiologic or experimental studies (from January 2000 to October 2015), then for systematic reviews and meta-analyses.

**DATA EXTRACTION: **
Data were extracted independently, after removing duplicates and studies that were not relevant or not pertinent.

**RESULTS: **
Abrupt discontinuation of treatment-exposed mothers with bipolar disorder or schizophrenia led to a high risk of relapses during pregnancy. Both bipolar disorder and schizophrenia were linked to a slightly increased risk of obstetric complications for mothers (schizophrenia) and the newborn (bipolar disorder and schizophrenia), although data on drug exposure during pregnancy were not given in the majority of studies. Maternal morbidity (schizophrenia but not bipolar disorder) may be associated with the worst neonatal outcomes (stillbirth, neonatal or infant deaths, and intellectual disability). Untreated bipolar disorder and schizophrenia may be considered independent risk factors for congenital malformations, while SGAs were not associated with increased recurring defects in fetuses. Evidence regarding the potential effects of SGAs on child neurodevelopment remains reassuring.

**CONCLUSION: **
After taking into account the parents&#039; will and after they provide informed consent, the most reasonable and less harmful choice for treating future mothers with bipolar disorder or schizophrenia appears to be maintaining them at the safest minimum dosage.
AD  - Tosato, Sarah. Section of Psychiatry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Policlinico GB Rossi, Ple LA Scuro 10, 37134 Verona (VR), Italy. sarah.tosato@univr.it.Tosato, Sarah. Section of Psychiatry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy.Albert, Umberto. Rita Levi Montalcini Department of Neuroscience, University of Turin, Italy, and San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy.Tomassi, Simona. Section of Psychiatry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy.Iasevoli, Felice. Department of Neuroscience, Reproductive Sciences and Odontostomatology, University &quot;Federico II&quot; of Naples, Italy.Carmassi, Claudia. Department of Clinical and Experimental Medicine, University of Pisa, Italy.Ferrari, Silvia. Department of Diagnostic-Clinical Medicine and Public Health, University of Modena and Reggio Emilia, Modena, Italy.Nanni, Maria Giulia. Institute of Psychiatry, Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Italy.Nivoli, Alessandra. Institute of Psychiatry, University of Sassari, Italy.Volpe, Umberto. Department of Psychiatry, University of Naples SUN, Naples, Italy.Atti, Anna Rita. Department of Biomedical and Neuromotor Sciences, University of Bologna, Italy.Fiorillo, Andrea. Department of Psychiatry, University of Naples SUN, Naples, Italy.
AN  - 28297592
AU  - Tosato,
AU  - S.
AU  - Albert,
AU  - U.
AU  - Tomassi,
AU  - S.
AU  - Iasevoli,
AU  - F.
AU  - Carmassi,
AU  - C.
AU  - Ferrari,
AU  - S.
AU  - Nanni,
AU  - M.
AU  - G.
AU  - Nivoli,
AU  - A.
AU  - Volpe,
AU  - U.
AU  - Atti,
AU  - A.
AU  - R.
AU  - Fiorillo,
AU  - A.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4088/JCP.15r10483
DP  - Ovid Technologies
J2  - J Clin Psychiatry
KW  - Adult
KW  - *Antipsychotic Agents/ae [Adverse Effects]
KW  - *Antipsychotic Agents/tu [Therapeutic Use]
KW  - Bipolar Disorder/di [Diagnosis]
KW  - *Bipolar Disorder/dt [Drug Therapy]
KW  - Bipolar Disorder/px [Psychology]
KW  - Female
KW  - Humans
KW  - Infant, Newborn
KW  - Intellectual Disability/ci [Chemically Induced]
KW  - Perinatal Death
KW  - Pregnancy
KW  - Pregnancy Complications/di [Diagnosis]
KW  - *Pregnancy Complications/dt [Drug Therapy]
KW  - Pregnancy Complications/px [Psychology]
KW  - Pregnancy Outcome
KW  - Recurrence
KW  - Risk
KW  - Schizophrenia/di [Diagnosis]
KW  - *Schizophrenia/dt [Drug Therapy]
KW  - Schizophrenic Psychology
KW  - Stillbirth
KW  - 0 (Antipsychotic Agents)
L1  - internal-pdf://1346381977/Tosato-2017-A Systematized Review of Atypical.pdf
LA  - English
M3  - Review
N1  - Tosato, SarahAlbert, UmbertoTomassi, SimonaIasevoli, FeliceCarmassi, ClaudiaFerrari, SilviaNanni, Maria GiuliaNivoli, AlessandraVolpe, UmbertoAtti, Anna RitaFiorillo, Andrea15r10483
PY  - 2017
SP  - e477-e489
T2  - Journal of Clinical Psychiatry
TI  - A Systematized Review of Atypical Antipsychotics in Pregnant Women: Balancing Between Risks of Untreated Illness and Risks of Drug-Related Adverse Effects
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=28297592
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28297592&amp;id=doi:10.4088%2FJCP.15r10483&amp;issn=0160-6689&amp;isbn=&amp;volume=78&amp;issue=5&amp;spage=e477&amp;pages=e477-e489&amp;date=2017&amp;title=Journal+of+Clinical+Psychiatry&amp;atitle=A+Systematized+Review+of+Atypical+Antipsychotics+in+Pregnant+Women%3A+Balancing+Between+Risks+of+Untreated+Illness+and+Risks+of+Drug-Related+Adverse+Effects.&amp;aulast=Tosato&amp;pid=%3Cauthor%3ETosato+S%3C%2Fauthor%3E%3CAN%3E28297592%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://www.psychiatrist.com/JCP/article/Pages/2017/v78n05/v78n0502.aspx
VL  - 78
ER  -
TY  - JOUR
AB  - BAKGRUNN
Foreliggende kunnskapsoppsummering er en vurdering av effekt av tiltakene Mestringskatten og Mestringskatten for ungdom. Artikkelen er en revisjon av tidligere beskrivelse av samme tiltak i Ungsinn (Bratt, 2010), men videreutviklet ut fra nye prosedyrer og kriterier i Ungsinn fra 2016 (Martinussen et al., 2016). Mestringskatten er et manualbasert program for behandling av barn og ungdom med angstplager eller angstlidelser og finnes i to versjoner; Mestringskatten (7-13 år) og Mestringskatten for ungdom (14-17 år). Programmet består av en arbeidsbok for barnet eller ungdommen og en manual for terapeuten. Barneversjonen av programmet omfatter 12 samlinger for barnet, mens ungdomsversjonen består av 14 samlinger. Begge versjonene inkluderer i tillegg to separate foreldresamlinger. Målgruppe for tiltaket er barn og ungdom med separasjonsangstlidelse (SAD), sosial angstlidelse (SOP) og/eller generalisert angstlidelse (GAD). Rettighetshaver i Norge er Universitetsforlaget (www.universitetsforlaget.no).

METODE
Foreliggende kunnskapsoppsummering bygger på systematisk litteratursøk i databasene Mbase, Medline, Psykinfo, NORART, Cochrane, Cristin, NORA, SCOPUS, SweMed, Kunnskapssenteret, NREPP, NICE, Blueprint og CEBC. Det ble også innhentet informasjon fra fagansvarlige for programmet ved RBUP Øst og Sør.

RESULTATER
Resultatene omfatter en oppsummering av tiltakets beskrivelse, foreliggende forskningsstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Tiltakets bakgrunn, innhold og metoder er godt beskrevet gjennom strukturerte og detaljerte terapeutmanualer og arbeidsbøker for henholdsvis barn og ungdom. Tiltaket har god teoretisk forankring. Det foreligger en rekke kvalitetsmessig gode internasjonale effektstudier og metaanalyser av barneversjonen av det opprinnelige amerikanske tiltaket (Coping Cat), hvor effekt av tiltaket er dokumentert. Det har vært gjennomført &eacute;n RCT studie av Mestringskatten i Norge. Resultatene herfra er ikke publisert og kan derfor ikke vurderes med hensyn til kvalitet og utfall. Vi kan ut fra dette ikke vise til om tiltaket har effekt når det anvendes i vanlig praksis i Norge. Programmet (både barne- og ungdomsversjonen) kan kjøpes i bokhandel. Det er ikke krav til opplæring, kvalifikasjoner eller tiltak for å sikre god implementeringskvalitet. Det tilbys et to-dagers frivillig kurs i Mestringskatten, hvor veiledning også kan gjøres tilgjengelig. Manglende systematisk oppfølging av implementering av tiltaket bidrar til usikkerhet ved kvaliteten ved bruken av Mestringskatten i vanlig praksis i Norge.

KONKLUSJON
En rekke internasjonale studier, kunnskapsoppsummeringer og metastudier med høy forskningskvalitet har vist god effekt av den amerikanske barneversjonen av Mestringskatten (Coping Cat). For å konkludere om den norske versjonen av tiltaket er virksomt i vanlig praksis i Norge, trenger vi gode effektstudier, eventuelt at resultatene fra studien som allerede er gjennomført blir publisert.

Mestringskatten klassifiseres på evidensnivå 3 &ndash; Tiltak med noe dokumentasjon på effekt
AU  - Haugland,
AU  - B.
AU  - S.,
AU  - Bjåstad,
AU  - J.,
AU  - F.,
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2017
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Mestringskatten (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/mestringskatten-2-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - **Background**
A number of school systems worldwide have proposed and implemented later school start times as a means of avoiding the potentially negative impacts that early morning schedules can have on adolescent students. Even mild sleep deprivation has been associated with significant health and educational concerns: increased risk for accidents and injuries, impaired learning, aggression, memory loss, poor self-esteem, and changes in metabolism. Although researchers have begun to explore the effects of delayed school start time, no one has conducted a rigorous review of evidence to determine whether later school start times support adolescent health, education, and well-being.

**Objectives**
We aimed to assess the effects of a later school start time for supporting health, education, and well-being in high school students.Secondary objectives were to explore possible differential effects of later school start times in student subgroups and in different types of schools; to identify implementation practices, contextual factors, and delivery modes associated with positive and negative effects of later start times; and to assess the effects of later school start times on the broader community (high school faculty and staff, neighborhood, and families).

**Search methods**
We conducted the main search for this review on 28 October 2014 and updated it on 8 February 2016. We searched CENTRAL as well as 17 key electronic databases (including MEDLINE, Embase, ERIC, PsycINFO, and Sociological Abstracts), current editions of relevant journals and organizational websites, trial registries, and Google Scholar.

**Selection criteria**
We included any randomized controlled trials, controlled before-and-after studies, and interrupted time series studies with sufficient data points that pertained to students aged 13 to 19 years and that compared different school start times. Studies that reported either primary outcomes of interest (academic outcomes, amount or quality of sleep, mental health indicators, attendance, or alertness) or secondary outcomes (health behaviors, health and safety indicators, social outcomes, family outcomes, school outcomes, or community outcomes) were eligible.

**Data collection and analysis**
At least two review authors independently determined inclusion and exclusion decisions through screening titles, abstracts, and full-text reports. Two review authors independently extracted data for all eligible studies. We presented findings through a narrative synthesis across all studies. When two or more study samples provided sufficient information to permit effect size calculations, we conducted random-effects meta-analyses to synthesize effects across studies.

**Main results**
Our search located 17 eligible records reporting on 11 unique studies with 297,994 participants; the studies examined academic outcomes, amount and quality of sleep, mental health indicators, attendance, and student alertness. Overall, the quality of the body of evidence was very low, as we rated most studies as being at high or unclear risk of bias with respect to allocation, attrition, absence of randomization, and the collection of baseline data. Therefore, we cannot be confident about the effects of later school start times.Preliminary evidence from the included studies indicated a potential association between later school start times and academic and psychosocial outcomes, but quality and comparability of these data were low and often precluded quantitative synthesis. Four studies examined the association between later school start times and academic outcomes, reporting mixed results. Six studies examined effects on total amount of sleep and reported significant, positive relationships between later school start times and amount of sleep. One study provided information concerning mental health outcomes, reporting an association between decreased depressive symptoms and later school start times. There were mixed results for the association between later school start times and absenteeism. Three studies reported mixed results concerning the association between later school start times and student alertness. There was limited indication of potential adverse effects on logistics, as the qualitative portions of one study reported less interaction between parents and children, and another reported staffing and scheduling difficulties. Because of the insufficient evidence, we cannot draw firm conclusions concerning adverse effects at this time.It is important to note the limitations of this evidence, especially as randomized controlled trials and high-quality primary studies are difficult to conduct; school systems are often unwilling or unable to allow researchers the necessary control over scheduling and data collection. Moreover, this evidence does not speak to the process of implementing later school starts, as the included studies focused on reporting the effects rather than exploring the process.

**Authors&#039; conclusions**
This systematic review on later school start times suggests several potential benefits for this intervention and points to the need for higher quality primary studies. However, as a result of the limited evidence base, we could not determine the effects of later school start times with any confidence.
AU  - Marx,
AU  - R.
AU  - Tanner-Smith,
AU  - E.
AU  - Davison,
AU  - C.
AU  - Ufholz,
AU  - L.
AU  - A.
AU  - Freeman,
AU  - J.
AU  - Shankar,
AU  - R.
AU  - Newton,
AU  - L.
AU  - Brown,
AU  - R.
AU  - S.
AU  - Parpia,
AU  - A.
AU  - Cozma,
AU  - I.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009467.pub2_
L1  - internal-pdf://4058877615/Robert Marx-2017-Later school start times for.pdf
PY  - 2017
T2  - Cochrane Database of Systematic Reviews
TI  - Later school start times for supporting the education, health, and well-being of high school students
UR  - http://onlinelibrary.wiley.com/store/10.1002/14651858.CD009467.pub2/asset/CD009467.pdf?v=1&amp;t=j82wpplr&amp;s=ef366a680c6ca1606486b52ebd564ad2fecdbb7d
VL  - 7
ER  -
TY  - JOUR
AB  - Depression and anxiety in children and young people with autism spectrum disorders (CYP with ASD) are relatively prevalent. 

Social skills deficits may be risk factors for the development of mood difficulties. This systematic review examined existing literature to establish whether social skills interventions positively influence mood in CYP with ASD. 

The majority of studies found that interventions improved mood, although there was heterogeneity in interventions and outcome reporting. 

As there is evidence that social skills interventions positively influence mood, future research should investigate the preventative effect of these interventions in moderating progression to clinical depression and anxiety in this population. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-11199-003
AU  - Rumney,
AU  - H.
AU  - L.
AU  - MacMahon,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.mhp.2016.12.001
L1  - internal-pdf://1142901747/Rumney-2017-Do social skills interventions pos.pdf
PY  - 2017
SP  - 12-20
TI  - Do social skills interventions positively influence mood in children and young people with autism? A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-11199-003
VL  - 5
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Digital health interventions (DHIs), including computer-assisted therapy, smartphone apps and wearable technologies, are heralded as having enormous potential to improve uptake and accessibility, efficiency, clinical effectiveness and personalisation of mental health interventions. It is generally assumed that DHIs will be preferred by children and young people (CYP) given their ubiquitous digital activity. However, it remains uncertain whether: DHIs for CYP are clinically and cost-effective, CYP prefer DHIs to traditional services, DHIs widen access and how they should be evaluated and adopted by mental health services. This review evaluates the evidence-base for DHIs and considers the key research questions and approaches to evaluation and implementation. 

**METHODS: **
We conducted a meta-review of scoping, narrative, systematic or meta-analytical reviews investigating the effectiveness of DHIs for mental health problems in CYP. We also updated a systematic review of randomised controlled trials (RCTs) of DHIs for CYP published in the last 3 years. 

**RESULTS: **
Twenty-one reviews were included in the meta-review. The findings provide some support for the clinical benefit of DHIs, particularly computerised cognitive behavioural therapy (cCBT), for depression and anxiety in adolescents and young adults. The systematic review identified 30 new RCTs evaluating DHIs for attention deficit/hyperactivity disorder (ADHD), autism, anxiety, depression, psychosis, eating disorders and PTSD. The benefits of DHIs in managing ADHD, autism, psychosis and eating disorders are uncertain, and evidence is lacking regarding the cost-effectiveness of DHIs. 

**CONCLUSIONS: **
Key methodological limitations make it difficult to draw definitive conclusions from existing clinical trials of DHIs. Issues include variable uptake and engagement with DHIs, lack of an agreed typology/taxonomy for DHIs, small sample sizes, lack of blinded outcome assessment, combining different comparators, short-term follow-up and poor specification of the level of human support. Research and practice recommendations are presented that address the key research questions and methodological issues for the evaluation and clinical implementation of DHIs for CYP. 

Copyright &copy; 2016 Association for Child and Adolescent Mental Health.
AN  - 27943285
AU  - Hollis,
AU  - C.
AU  - Falconer,
AU  - C.
AU  - J.
AU  - Martin,
AU  - J.
AU  - L.
AU  - Whittington,
AU  - C.
AU  - Stockton,
AU  - S.
AU  - Glazebrook,
AU  - C.
AU  - Davies,
AU  - E.
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.12663
L1  - internal-pdf://3644226177/Hollis-2017-Annual Research Review_ Digital he.pdf
PY  - 2017
SP  - 474-503
TI  - Annual Research Review: Digital health interventions for children and young people with mental health problems - a systematic and meta-review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27943285
VL  - 58
ER  -
TY  - JOUR
AB  - **Objective. **
To summarize and evaluate the efficacy and safety of herbal medicines used for the treatment of autism spectrum disorder (ASD) in children. 

**Methods. **
Thirteen electronic databases were searched from their inception to November 2016. Randomized controlled trials (RCTs) that assessed the efficacy of herbal medicines alone or in combination with other Traditional Chinese Medicine treatments for ASD in children were included. The Cochrane Risk of Bias Tool was used and other data analyses were performed using RevMan (Version 5.3). 

**Results. **
Ten RCTs involving 567 patients with ASD were included for qualitative synthesis. In conjunction with conventional therapy, herbal medicines significantly improved the Childhood Autism Rating Scale (CARS) score, but the results of effects on total effective rate (TER) were different between the included studies. The use of herbal medicines with integrative therapy improved the CARS score and TER. In the studies that documented adverse events, no serious events were associated with herbal medicines. 

**Conclusions. **
The efficacy of herbal medicines for the treatment of ASD appears to be encouraging but was inconclusive owing to low methodological quality, herbal medicine diversity, and small sample size of the examined studies. 

Copyright &copy; 2017 Miran Bang et al.
AN  - 616511227
AU  - Bang,
AU  - M.
AU  - Lee,
AU  - S.
AU  - H.
AU  - Cho,
AU  - S.
AU  - H.
AU  - Yu.
AU  - S.
AU  - A.
AU  - Kim,
AU  - K.
AU  - Lu,
AU  - H.
AU  - Y.
AU  - Chang,
AU  - G.
AU  - T.
AU  - Min,
AU  - S.
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1155/2017/8614680
L1  - internal-pdf://3393345727/Bang-2017-Herbal Medicine Treatment for Childr.pdf
PY  - 2017
TI  - Herbal Medicine Treatment for Children with Autism Spectrum Disorder: A Systematic Review
UR  - http://www.hindawi.com/journals/ecam/contents.html
VL  - 2017 (no pagination)
ER  -
TY  - JOUR
AB  - **Background: **
Anxiety disorders are common, often start in childhood and run a chronic course. As such there is a need for effective prevention. 

**Methods: **
We conducted a systematic review and meta-analyses of randomized, controlled trials to prevent the onset of anxiety disorders in &#039;at risk&#039; young people. Diagnostic and symptom outcomes were examined. Putative moderators were tested as was publication bias. 

**Results:** 
We included 16 trials (2545 young people). Two trials reported diagnostic outcomes, and significant effects were found for these at end-of-programme (RR =.09, 95%CI =.02 to.16), 6- (RR =.17, 95%CI =.06 to.27) and 12-month (RR =.31, 95%CI.17 to.45) follow-ups. Based on 16 trials, improved anxiety symptoms were significant compared to nonattention controls only, with small effect sizes reported by young people at the end-of-programmes, 6- and 12-month follow-ups; and by parents at the end of the programmes and 12-, but not 6-, month follow-ups. There was no evidence of significant moderation or publication bias. 

**Conclusions: **
Fourteen studies included children and young people who presented with elevated anxiety symptoms, but anxiety disorder was not ruled out in the participants in these studies. Hence, these studies might be reporting results of mixed prevention/early intervention programmes. Prevention programmes that target developmental risk factors, not only disorder maintaining factors, appear most promising. The clinically meaningful impact of anxiety disorder prevention programmes remains unknown. 

Copyright &copy; 2017 The Authors. Child and Adolescent Mental Health published by John Wiley &amp; Sons Ltd on behalf of Association for Child and Adolescent Mental Health
AN  - 617301133
AU  - Lawrence,
AU  - P.
AU  - J.
AU  - Rooke,
AU  - S.
AU  - M.
AU  - Creswell,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/camh.12226
L1  - internal-pdf://3439031682/Lawrence-2017-Review_ Prevention of anxiety am.pdf
PY  - 2017
SP  - 118-130
TI  - Review: Prevention of anxiety among at-risk children and adolescents - a systematic review and meta-analysis
UR  - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1475-3588
VL  - 22
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
Anxiety is more prevalent in children with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) than in the general population. A systematic review was carried out to identify which treatment methods are most effective for children with CFS and anxiety. 

**DESIGN: **
Systematic review using search terms entered into the Cochrane library and Ovid to search the databases Medline, Embase and psychINFO. 

**PARTICIPANTS: **
Studies were selected if participants were &lt;18 years old, diagnosed with CFS/ME (using US Centers for Disease Control and Prevention, the National Institute for Health and Care Excellence or Oxford criteria) and had a valid assessment of anxiety. 

**INTERVENTIONS: **
We included observational studies and randomised controlled trials. 

**COMPARISON: **
Any or none. 

**OUTCOMES: **
Change in anxiety diagnostic status and/or change in anxiety severity on a validated measure of anxiety from pretreatment to post-treatment. 

**RESULTS: **
The review identified nine papers from eight studies that met the inclusion criteria. None of the studies specifically targeted anxiety but six studies tested an intervention and measured anxiety as a secondary outcome. Of these studies, four used a cognitive behavioural therapy (CBT)-type approach to treat CFS/ME, one used a behavioural approach and one compared a drug treatment, gammaglobulin with a placebo. Three of the CBT-type studies described an improvement in anxiety as did the trial of gammaglobulin. As none of the studies stratified outcomes according to anxiety diagnostic status or severity, we were unable to determine whether anxiety changed prognosis or whether treatments were equally effective in those with comorbid anxiety compared with those without. 

**CONCLUSION: **
We do not know what treatment should be offered for children with both anxiety and CFS/ME. Further research is therefore required to answer this question. 

**TRIAL REGISTRATION NUMBER: **
This review was registered on Prospective Register of Systematic Review Protocols (PROSPERO) and the protocol is available from
AN  - 28877941
AU  - Stoll,
AU  - S.
AU  - V.
AU  - E.
AU  - Crawley,
AU  - E.
AU  - Richards,
AU  - V.
AU  - Lal,
AU  - N.
AU  - Brigden,
AU  - A.
AU  - Loades,
AU  - M.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmjopen-2016-015481
L1  - internal-pdf://4274189379/Stoll-2017-What treatments work for anxiety in.pdf
PY  - 2017
SP  - e015481
TI  - What treatments work for anxiety in children with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)? Systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28877941
VL  - 7
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Few meta-analyses have focused on the effect of cognitive behavioral therapy (CBT) for depression in children. 

**STUDY SELECTION: **
Randomized controlled trials comparing CBT with control conditions for depression in children (&lt;13 years old) were included. 

**DATA SOURCES: **
Seven electronic databases (PubMed, Embase, CENTRAL, Web of Science, PsycINFO, CINAHL, and LiLACS) were searched from inception to September 2015. 

**DATA EXTRACTION AND SYNTHESIS: **
The primary efficacy was defined as mean change scores in depressive symptoms, and the second efficacy (remission) was a score below the threshold for a diagnosis of depression, both after treatment and at the end of follow-up. We also measured acceptability by the proportion of participants who discontinued treatment up to posttreatment. 

**RESULTS:**
Nine studies with 306 participants were selected for this analysis. At posttreatment, CBT was significantly more effective than control conditions in terms of primary efficacy (standardized mean difference, -0.41; 95% confidence interval [CI], -0.64 to -0.18) and secondary efficacy (odds ratio [OR], 2.16; 95% CI, 1.24 to 3.78). At follow-up, the results were consistent with those of efficacy outcomes at posttreatment, with a standardized mean difference of -0.34 and an OR of 2.04. CBT had no statistical more all-cause discontinuations than the control group (OR, 0.69; 95% CI, 0.26 to 1.82). However, subgroup analyses found that CBT was only significantly more effective than nontreatment, while it was not better than wait list or psychological placebo. 

**CONCLUSIONS: **
CBT seems to be more beneficial in the treatment of depression in children than nontreatment; however, this finding is limited by the small size of the trials and low literature quality. 

Copyright &copy; 2016 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.
AD  - Yang, Lining. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Zhou, Xinyu. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Zhou, Chanjuan. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Zhang, Yuqing. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Pu, Juncai. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Liu, Lanxiang. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Gong, Xue. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Xie, Peng. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: xiepeng973@126.com.
AN  - 27989281
AU  - Yang,
AU  - L.
AU  - Zhou,
AU  - X.
AU  - Zhou,
AU  - C.
AU  - Zhang,
AU  - Y.
AU  - Pu,
AU  - J.
AU  - Liu,
AU  - L.
AU  - Gong,
AU  - X.
AU  - Xie,
AU  - P.
DA  - Jan - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.acap.2016.08.002
DP  - Ovid Technologies
J2  - Acad Pediatr
L1  - internal-pdf://1996945413/Yang-2017-Efficacy and Acceptability of Cognit.pdf
LA  - English
M3  - Review
N1  - Yang, Lining Zhou, Xinyu Zhou, Chanjuan Zhang, Yuqing Pu, Juncai Liu, Lanxiang Gong, Xue Xie, Peng S1876-2859(16)30405-3
PY  - 2017
SP  - 9-16
T2  - Academic pediatrics
TI  - Efficacy and Acceptability of Cognitive Behavioral Therapy for Depression in Children: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27989281http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27989281&amp;id=doi:10.1016%2Fj.acap.2016.08.002&amp;issn=1876-2859&amp;isbn=&amp;volume=17&amp;issue=1&amp;spage=9&amp;pages=9-16&amp;date=2017&amp;title=Academic+pediatrics&amp;atitle=Efficacy+and+Acceptability+of+Cognitive+Behavioral+Therapy+for+Depression+in+Children%3A+A+Systematic+Review+and+Meta-analysis.&amp;aulast=Yang&amp;pid=%3Cauthor%3EYang+L%3C%2Fauthor%3E%3CAN%3E27989281%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S1876285916304053/1-s2.0-S1876285916304053-main.pdf?_tid=78555b58-04d2-11e7-a456-00000aacb360&amp;acdnat=1489068946_3d89247022cbb4c10741db5404838f56
VL  - 17
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
The purpose of this review is to identify evidence in herbal therapy in the treatment of ADHD concerning effectiveness and drug tolerability. 

**METHOD: **
For this Medline/PubMed, Scopus and the Cochrane Central Register of Controlled Trials (Central) were searched from their inception to 15 July 2016. Only randomized controlled trails (RCT) with children (0-18years) suffering from ADHD were included in this review. 

**RESULTS: **
Nine RCTs with 464 patients comparing herbal pharmaceuticals to placebo or active control were included. Seven different herbs were tested in the treatment of ADHD symptoms. Low evidence could be found for Melissa officinalis, Valeriana officinalis and Passiflora incarnata. Limited evidence could be found for pine bark extract and Gingko biloba. The other herbal preparations showed no efficacy in the treatment of ADHD symptoms.

**CONCLUSION: **
While there is still a lack of sufficient numbers of RCTs no concrete recommendations for use can be made so far. 

Copyright &copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Anheyer, Dennis. Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany. Electronic address: d.anheyer@kliniken-essen-mitte.de. Lauche, Romy. Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany; Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), University of Technology Sydney, Sydney, Australia. Schumann, Dania. Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany. Dobos, Gustav. Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany. Cramer, Holger. Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany; Australian Research Centre in Complementary and Integrative Medicine (ARCCIM), University of Technology Sydney, Sydney, Australia.
AN  - 28137522
AU  - Anheyer,
AU  - D.
AU  - Lauche,
AU  - R.
AU  - Schumann,
AU  - D.
AU  - Dobos,
AU  - G.
AU  - Cramer,
AU  - H.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ctim.2016.11.004
DP  - Ovid Technologies
J2  - Complement Ther Med
L1  - internal-pdf://0467304740/Anheyer-2017-Herbal medicines in children with.pdf
LA  - English
M3  - Review
N1  - Anheyer, Dennis Lauche, Romy Schumann, Dania Dobos, Gustav Cramer, Holger S0965-2299(16)30328-4
PY  - 2017
SP  - 14-23
T2  - Complementary Therapies in Medicine
TI  - Herbal medicines in children with attention deficit hyperactivity disorder (ADHD): A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28137522http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28137522&amp;id=doi:10.1016%2Fj.ctim.2016.11.004&amp;issn=0965-2299&amp;isbn=&amp;volume=30&amp;issue=&amp;spage=14&amp;pages=14-23&amp;date=2017&amp;title=Complementary+Therapies+in+Medicine&amp;atitle=Herbal+medicines+in+children+with+attention+deficit+hyperactivity+disorder+%28ADHD%29%3A+A+systematic+review.&amp;aulast=Anheyer&amp;pid=%3Cauthor%3EAnheyer+D%3C%2Fauthor%3E%3CAN%3E28137522%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0965229916303284/1-s2.0-S0965229916303284-main.pdf?_tid=c50831ac-04c1-11e7-8fb1-00000aacb35f&amp;acdnat=1489061774_2565b6cfbbc351c4ea9563d53061c714
VL  - 30
ER  -
TY  - JOUR
AB  - Attention-Deficit/Hyperactivity Disorder (ADHD) impacts a significant number of children and adolescents and often leads to deleterious functional impairment. Psychostimulant medication has historically been the first line of pharmacological intervention, though recent years have seen greater attention paid to non-stimulant alternatives. 

The objective of the present study was to conduct the most comprehensive meta-analysis to date evaluating the efficacy of atomoxetine in reducing core symptomatology of ADHD according to parent report. Selection criteria were applied, and studies were located by searching electronic databases, review of reference sections, and contact with expert researchers; article searching began on 10/01/2013, and the final search was conducted on 09/01/2014. 

A total of 42 studies met inclusion criteria-33 with control groups and 9 without-for a total sample of 8398 individuals. For those receiving atomoxetine, the summary pre-post (e.g., standardized mean gain) effect size estimate was 1.37 (95% CI [1.24, 1.51], p &lt; .001); atomoxetine was found to statistically significantly outperform control conditions overall (Z = 4.07, p &lt; .001), though results differed by the type of control group; for instance, when comparing atomoxetine to alternative medications as controls, significant differences were no longer present. 

The non-stimulant atomoxetine led to significant improvement in core ADHD symptomatology and should be considered as a viable pharmacological treatment option for ADHD. 

Copyright &copy; 2017, Springer-Verlag Wien.
AN  - 614148341
AU  - Gayleard,
AU  - J.
AU  - L.
AU  - Mychailyszyn,
AU  - M.
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s12402-017-0216-y
L1  - internal-pdf://3727048877/Gayleard-2017-Atomoxetine treatment for childr.pdf
PY  - 2017
SP  - 149-160
TI  - Atomoxetine treatment for children and adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD): a comprehensive meta-analysis of outcomes on parent-rated core symptomatology
UR  - http://www.springer.com/springerwiennewyork/medicine/journal/12402
VL  - 9
ER  -
TY  - JOUR
AB  - **Background &amp; Study Aim: **
Available publications regarding the use of martial arts in therapy and rehabilitation are main premises to this research. The purpose of this study was the issue whether martial arts are effective in improving clinical symptoms in individuals with autism spectrum disorder (ASD) so to provide better management guidelines for treatment of ASD. 

**Material &amp; Methods:**
Eight electronic databases were used for literature search, including PubMed, Cochrane Library, Google Scholar, Physiotherapy Evidence Database (PEDro), ProQuest, Research Autism, and CliniicalTrials.gov. After conducting the electronic search from September 2000 to August 2016, manual searches were subsequently performed through reference lists of the relevant publications. Methodological quality of 9 eligible studies was independently evaluated by two review authors using PEDro scales and the modified Clinical Relevance Tool. 

**Results: **
Inter-reliability for study selection was 90%. When inter-reliability for evaluating the study quality was 100%, methodological quality scores for 6 randomized controlled studies and 3 case studies ranged from 7 to 8 out of 10 and 6 out of 7, respectively. Study findings demonstrated that martial arts-based interventions (internal and external styles) had positive influence on ASD-related symptoms (e.g., social interaction/communication skills, self-regulation, memory, postural control, and cognitive function) with effect size ranging from medium to high. 

**Conclusions: **
Martial arts are beneficial for individuals with ASD. It should be incorporated into rehabilitation program to help symptomatic management of ASD. A combination of internal and external styles of martial arts for individuals with ASD to maximize the positive effect should be examined in the future study.
AN  - WOS:000404582800001
AU  - Zou,
AU  - L.
AU  - Xiao,
AU  - Z.
AU  - Wang,
AU  - H.
AU  - Wang,
AU  - C.
AU  - Hu,
AU  - X.
AU  - Shu,
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
L1  - internal-pdf://3448598472/Zou-2017-Martial arts for health benefits in c.pdf
PY  - 2017
SP  - 79-92
TI  - Martial arts for health benefits in children and youth with autism spectrum disorder: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000404582800001
VL  - 13
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
Attention-deficit/hyperactivity disorder (ADHD) is a debilitating mental health problem hampering the child&#039;s development. The underlying causes include both genetic and environmental factors and may differ between individuals. The efficacy of diet treatments in ADHD was recently evaluated in three reviews, reporting divergent and confusing conclusions based on heterogeneous studies and subjects. To address this inconsistency we conducted a systematic review of meta-analyses of double-blind placebo-controlled trials evaluating the effect of diet interventions (elimination and supplementation) on ADHD. 

**METHODS: **
Our literature search resulted in 14 meta-analyses, six of which confined to double-blind placebo-controlled trials applying homogeneous diet interventions, i.e. artificial food color (AFC) elimination, a few-foods diet (FFD) and poly-unsaturated fatty acid (PUFA) supplementation. Effect sizes (ES) and Confidence intervals (CI) of study outcomes were depicted in a forest plot. I2 was calculated to assess heterogeneity if necessary and additional random effects subgroup meta-regression was conducted if substantial heterogeneity was present. 

**RESULTS: **
The AFC ESs were 0.44 (95% CI: 0.16-0.72, I2 = 11%) and 0.21 (95% CI: -0.02-0.43, I2 = 68%) [parent ratings], 0.08 (95% CI: -0.07-0.24, I2 = 0%) [teacher ratings] and 0.11 (95% CI: -0.13-0.34, I2 = 12%) [observer ratings]. The FFD ESs were 0.80 (95% CI: 0.41-1.19, I2 = 61%) [parent ratings] and 0.51 (95% CI: -0.02-1.04, I2 = 72%) [other ratings], while the PUFA ESs were 0.17 (95% CI: -0.03-0.38, I2 = 38%) [parent ratings], -0.05 (95% CI: -0.27-0.18, I2 = 0%) [teacher ratings] and 0.16 (95% CI: 0.01-0.31, I2 = 0%) [parent and teacher ratings]. Three meta-analyses (two FFD and one AFC) resulted in high I2 without presenting subgroup results. The FFD meta-analyses provided sufficient data to perform subgroup analyses on intervention type, resulting in a decrease of heterogeneity to 0% (diet design) and 37.8% (challenge design). 

**CONCLUSION: **
Considering the small average ESs PUFA supplementation is unlikely to provide a tangible contribution to ADHD treatment, while further research is required for AFC elimination before advising this intervention as ADHD treatment. The average FFD ES is substantial, offering treatment opportunities in subgroups of children with ADHD not responding to or too young for medication. Further FFD research should focus on establishing the underlying mechanisms of food (e.g. incrimination of gut microbiota) to simplify the FFD approach in children with ADHD.
AD  - Pelsser, Lidy M. ADHD Research Centre, Eindhoven, the Netherlands. Frankena, Klaas. Quantitative Veterinary Epidemiology group, Wageningen University &amp; Research, Wageningen, the Netherlands. Toorman, Jan. Retired paediatrician, previously Catharina Hospital, Eindhoven, the Netherlands. Rodrigues Pereira, Rob. Medical Center Kinderplein, Rotterdam, the Netherlands.
AN  - 28121994
AU  - Pelsser,
AU  - L.
AU  - M.
AU  - Frankena,
AU  - K.
AU  - Toorman,
AU  - J.
AU  - Rodrigues,
AU  - B.
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0169277
DP  - Ovid Technologies
J2  - PLoS ONE
L1  - internal-pdf://3290865165/Pelsser-2017-Diet and ADHD, Reviewing the Evid.pdf
LA  - English
N1  - Pelsser, Lidy M Frankena, Klaas Toorman, Jan Rodrigues Pereira, Rob PONE-D-16-17645
PY  - 2017
SP  - e0169277
T2  - PLoS ONE [Electronic Resource]
TI  - Diet and ADHD, Reviewing the Evidence: A Systematic Review of Meta-Analyses of Double-Blind Placebo-Controlled Trials Evaluating the Efficacy of Diet Interventions on the Behavior of Children with ADHD
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28121994http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28121994&amp;id=doi:10.1371%2Fjournal.pone.0169277&amp;issn=1932-6203&amp;isbn=&amp;volume=12&amp;issue=1&amp;spage=e0169277&amp;pages=e0169277&amp;date=2017&amp;title=PLoS+ONE+%5BElectronic+Resource%5D&amp;atitle=Diet+and+ADHD%2C+Reviewing+the+Evidence%3A+A+Systematic+Review+of+Meta-Analyses+of+Double-Blind+Placebo-Controlled+Trials+Evaluating+the+Efficacy+of+Diet+Interventions+on+the+Behavior+of+Children+with+ADHD.&amp;aulast=Pelsser&amp;pid=%3Cauthor%3EPelsser+LM%3C%2Fauthor%3E%3CAN%3E28121994%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0169277&amp;type=printable
VL  - 12
ER  -
TY  - JOUR
AB  - **Objective **
The aim of this study was to evaluate the efficacy and safety of clonidine adhesive patch for tic disorders (TDs). 

**Methods **
Medline, Embase, Cochrane central register of controlled trials and Chinese databases of CBM, CNKI were searched from inception to 08.2016 for randomized controlled studies (RCTs), open-label control studies of clonidine adhesive patch versus other medications or/and placebo for TDs. The cochrane Handbook for Systematic Reviews of Interventions was used to guide our study. 

**Results **
Six studies involving 1145 participants were included in this study. Among these studies, two study (N = 513 patients) used placebo as a control and four studies (N = 632 patients) used positive drug controls. The results of meta-analysis suggested that clonidine adhesive patch may be as effective as haloperidol or tiapride for TDs. Adverse events (AEs) were reported in all studies, and the most common AEs of clonidine adhesive patch were rash (8.9%), lightheadedness (8.0%), dry mouth (4.0%). The AEs of clonidine adhesive patch were slight. 

**Conclusion **
These data provide moderate quality evidence that clonidine adhesive patch might be an effective and safe treatment option for TDs, and results from further trials are urgently needed to extend the evidence base. Copyright &copy; 2017 European Paediatric Neurology Society
AN  - 616065019
AU  - Wang,
AU  - S.
AU  - Wei,
AU  - Y.
AU  - Z.
AU  - Yang,
AU  - J.
AU  - Zhou,
AU  - Y.
AU  - Zheng,
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ejpn.2017.03.003
L1  - internal-pdf://2135776765/Wang-2017-Clonidine adhesive patch for the tre.pdf
PY  - 2017
SP  - 614-620
TI  - Clonidine adhesive patch for the treatment of tic disorders: A systematic review and meta-analysis
UR  - http://www.elsevier.com/inca/publications/store/6/2/3/0/3/2/index.htt
VL  - 21
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The management of depressive and mixed symptoms in children and adolescents with bipolar disorder (BD) remains a matter of debate. The goal of this review is, thus, to systematically examine the impact of atypical antipsychotics (AAPs) and mood stabilisers in the treatment of bipolar depression and/or mixed states. 

**METHODS: **
A literature search was conducted for studies assessing the efficacy of pharmacological treatments for bipolar disorder type I, type II and not otherwise specified with a recent depressive, mixed or manic episode (with depressive symptoms) following DSM-IV criteria in children and adolescents as either acute or maintenance treatment. The databases searched were PubMed/Medline, Google Scholar and Tripdatabase, as well as ClinicalTrials.gov. The search was limited to clinical trials, systematic reviews, meta-analyses and open-label trials published in the English language between the years 2000 and 2015. Sixty clinical studies were found assessing the efficacy of mood stabilisers and AAPs in paediatric BD. Fifteen studies were not included in the primary analysis because they did not assess depressive symptomology/include scores on rating scales of depressive symptoms (Online Supplementary Material). 

**RESULTS: **
There is sufficient evidence for a Grade A recommendation of the use of olanzapine plus fluoxetine at reducing depressive symptoms in bipolar depression and of quetiapine at high doses for depressive symptoms occurring during mixed episodes. Importantly, even though monotherapy with aripiprazole, risperidone, valproate and lithium was effective at controlling mania, these drugs were not effective at reducing depressive symptoms (level A evidence for nonrecommendation). 

**CONCLUSIONS:**
These results mostly overlap with the approved treatments for bipolar depression in adults.
AN  - 28474733
AU  - Atkin,
AU  - T.
AU  - Nunez,
AU  - N.
AU  - Gobbi,
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.12735
L1  - internal-pdf://3392737901/Atkin-2017-Practitioner Review_ The effects of.pdf
N1  - Kristine Ludvigsen (2017-12-14 20:04:31)(Select): I tvil pga måten de har slått sammen og rapportert resultater... Men Numdata beskrives i supp:
PY  - 2017
SP  - 865-879
TI  - Practitioner Review: The effects of atypical antipsychotics and mood stabilisers in the treatment of depressive symptoms in paediatric bipolar disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28474733
VL  - 58
ER  -
TY  - JOUR
AB  - Antenatal and postpartum depression are very common and have significant consequences for mothers and their children. This review examines which antenatal depression (AD) and postpartum depression (PPD) treatment interventions are most efficacious in improving parenting and/or child development. CINAHL, Scopus, Cochrane Systematic Reviews, Cochrane Controlled Trials, Medline (OVID), Embase (OVID), PsychINFO, PsycARTICLES, AMED, and reference lists were searched. 

Randomized controlled trials (RCTs) and quasi-experimental studies assessing the effect of AD, PPD, or both treatment interventions on parenting and/or child development were included. Meta-analysis was conducted using random effects when possible. Thirty-six trials (within 40 articles) met criteria for review. Interventions include interpersonal psychotherapy (IPT), cognitive behavioural therapy (CBT), peer support, maternal-child interaction guidance, and other interventions, such as massage. 

For AD, IPT, CBT, and massage produced large effects on parenting (e.g. adjustment and attention toward infant) and child development (e.g. behaviour). For PPD, maternal-child interaction guidance and psychotherapeutic group support produced large effects on parenting (e.g. sense of competence) and child development (e.g. cortisol). However, meta-analysis revealed nonsignificant effects of IPT on maternal-child attachment and CBT on parenting stress. 

Promising findings exist for IPT, CBT, maternal-child interaction guidance, massage, and psychotherapeutic group support for specific parenting and/or child development outcomes. Additional RCTs using measures already employed in the literature are required to conduct necessary meta-analysis and fully elucidate treatment effects. 

Copyright &copy; 2017 Wiley Periodicals, Inc.
AN  - 618638228
AU  - Letourneau,
AU  - N.
AU  - L.
AU  - Dennis,
AU  - C.
AU  - L.
AU  - Cosic,
AU  - N.
AU  - Linder,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/da.22687
L1  - internal-pdf://4056133603/Letourneau-2017-The effect of perinatal depres.pdf
PY  - 2017
SP  - 928-966
TI  - The effect of perinatal depression treatment for mothers on parenting and child development: A systematic review
UR  - http://www.interscience.wiley.com/jpages/1091-4269
VL  - 34
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Parent training programs for families living outside of urban areas can be used to improve the social behavior and communication skills in children with autism spectrum disorder (ASD). However, no review has been conducted to investigate these programs. 

**OBJECTIVE: **
The aim of this study was to (1) systematically review the existing evidence presented by studies on parent-mediated intervention training, delivered remotely for parents having children with ASD and living outside of urban areas; (2) provide an overview of current parent training interventions used with this population; (3) and provide an overview of the method of delivery of the parent training interventions used with this population. 

**METHODS: **
Guided by the preferred reporting items for systematic reviews and meta-analyses (PRISMA) statement, we conducted a comprehensive review across 5 electronic databases (CINAHL, Embase, ERIC, PsycINFO, and Pubmed) on July 4, 2016, searching for studies investigating parent-mediated intervention training for families living outside of urban centers who have a child diagnosed with ASD. Two independent researchers reviewed the articles for inclusion, and assessment of methodological quality was based on the Kmet appraisal checklist. 

**RESULTS: **
Seven studies met the eligibility criteria, including 2 prepost cohort studies, 3 multiple baseline studies, and 2 randomized controlled trials (RCTs). Interventions included mostly self-guided websites: with and without therapist assistance (n=6), with training videos, written training manuals, and videoconferencing. Post intervention, studies reported significant improvements (P&lt;.05) in parent knowledge (n=4), parent intervention fidelity (n=6), and improvements in children&#039;s social behavior and communication skills (n=3). A high risk of bias existed within all of the studies because of a range of factors including small sample sizes, limited use of standardized outcome measures, and a lack of control groups to negate confounding factors. 

**CONCLUSIONS: **
There is preliminary evidence that parent-mediated intervention training delivered remotely may improve parent knowledge, increase parent intervention fidelity, and improve the social behavior and communication skills for children with ASD. A low number of RCTs, difficulty in defining the locality of the population, and a paucity of standardized measures limit the generalization of the findings to the target population. Future studies should investigate the appropriateness and feasibility of the interventions, include RCTs to control for bias, and utilize standard outcome measures.
AN  - 28807892
AU  - Parsons,
AU  - D.
AU  - Cordier,
AU  - R.
AU  - Vaz,
AU  - S.
AU  - Lee,
AU  - H.
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2196/jmir.6651
L1  - internal-pdf://2012357360/Parsons-2017-Parent-Mediated Intervention Trai.pdf
PY  - 2017
SP  - e198
TI  - Parent-Mediated Intervention Training Delivered Remotely for Children With Autism Spectrum Disorder Living Outside of Urban Areas: Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28807892
VL  - 19
ER  -
TY  - JOUR
AB  - Quality of child care has been shown to have a crucial impact on children&#039;s development and psychological adjustment, particularly for orphans with a history of maltreatment and trauma. However, adequate care for orphans is often impacted by unfavorable caregiver-child ratios and poorly trained, overburdened personnel, especially in institutional care in countries with limited resources and large numbers of orphans. 

This systematic review investigated the effects of structural interventions and caregiver trainings on child development in institutional environments. The 24 intervention studies included in this systematic review reported beneficial effects on the children&#039;s emotional, social, and cognitive development. Yet, few studies focused on effects of interventions on the child-caregiver relationship or the general institutional environment. 

Moreover, our review revealed that interventions aimed at improving institutional care settings have largely neglected violence and abuse prevention. Unfortunately, our findings are partially limited by constraints of study design and methodology. In sum, this systematic review sheds light on obstacles and possibilities for the improvement in institutional care. There must be greater efforts at preventing violence, abuse, and neglect of children living in institutional care. 

Therefore, we advocate for combining attachment theory-based models with maltreatment prevention approaches and then testing them using rigorous scientific standards. By using approaches grounded in the evidence, it could be possible to enable more children to grow up in supportive and nonviolent environments.
AN  - WOS:000414716400006
AU  - Hermenau,
AU  - K.
AU  - Goessmann,
AU  - K.
AU  - Rygaard,
AU  - N.
AU  - P.
AU  - Landolt,
AU  - M.
AU  - A.
AU  - Hecker,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1524838016641918
L1  - internal-pdf://2176530859/Hermenau-2017-Fostering Child Development by I.pdf
PY  - 2017
SP  - 544-561
T2  - Trauma Violence &amp; Abuse
TI  - Fostering Child Development by Improving Care Quality: A Systematic Review of the Effectiveness of Structural Interventions and Caregiver Trainings in Institutional Care
UR  - &lt;Go to ISI&gt;://WOS:000414716400006
VL  - 18
ER  -
TY  - JOUR
AB  - This meta-analysis examines the effectiveness of interactive middle school-based drug prevention programs on adolescent cannabis use in North America, as well as program characteristics that could moderate these effects. Interactive programs, compared to more didactic, lecture style programs, involve participants in skill-building activities and focus on interaction among participants. 

A systematic literature search was conducted for English-language studies from January 1998 to March 2014. Studies included evaluations using random assignment or a quasi-experimental design of interactive school-based substance use prevention programs delivered to adolescents (aged 12-14) in North American middle schools (grades 6-8). Data were extracted using a coding protocol. 

The outcomes of interest were post-treatment cannabis use, intent to use, and refusal skills compared across intervention and control groups. Effect sizes (Cohen&#039;s d) were calculated from continuous measures, and dichotomous measures were converted to the d index. A total of 30 studies yielding 23 independent samples were included. 

The random effects pooled effect size for cannabis use (k=21) was small ([Formula: see text]= -0.07, p&lt;0.01) and favorable for the prevention programs. The pooled effect sizes for intention to use (k=3) and refusal skills (k=3) were not significant. Moderator analyses indicated significant differences in program effectiveness between instructor types, with teachers found to be most effective ([Formula: see text]= -0.08, p=0.02). 

The findings provide further support for the use of interactive school-based programs to prevent cannabis use among middle school students in North America.
AD  - Lize, Steven E. College of Social Work, University of South Carolina, Hamilton 308, Columbia, SC, 29208, USA. lize.steve@gmail.com. Iachini, Aidyn L. College of Social Work, University of South Carolina, Hamilton 308, Columbia, SC, 29208, USA. Tang, Weizhou. College of Social Work, University of South Carolina, Hamilton 308, Columbia, SC, 29208, USA. Tucker, Joshua. College of Social Work, University of South Carolina, Hamilton 308, Columbia, SC, 29208, USA. Seay, Kristen D. College of Social Work, University of South Carolina, Hamilton 308, Columbia, SC, 29208, USA. Clone, Stephanie. College of Social Work, University of South Carolina, Hamilton 308, Columbia, SC, 29208, USA. DeHart, Dana. College of Social Work, University of South Carolina, Hamilton 308, Columbia, SC, 29208, USA. Browne, Teri. College of Social Work, University of South Carolina, Hamilton 308, Columbia, SC, 29208, USA.
AN  - 27785662
AU  - Lize,
AU  - S.
AU  - E.
AU  - Iachini,
AU  - A.
AU  - L.
AU  - Tang,
AU  - W.
AU  - Tucker,
AU  - J.
AU  - Seay,
AU  - K.
AU  - D.
AU  - Clone,
AU  - S.
AU  - DeHart,
AU  - D.
AU  - Browne,
AU  - T.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s11121-016-0723-7
DP  - Ovid Technologies
J2  - Prev Sci
L1  - internal-pdf://0645418161/Lize-2017-A Meta-analysis of the Effectiveness.pdf
LA  - English
N1  - Lize, Steven E Iachini, Aidyn L Tang, Weizhou Tucker, Joshua Seay, Kristen D Clone, Stephanie DeHart, Dana Browne, Teri 10.1007/s11121-016-0723-7
PY  - 2017
SP  - 50-60
T2  - Prevention Science
TI  - A Meta-analysis of the Effectiveness of Interactive Middle School Cannabis Prevention Programs
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27785662http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27785662&amp;id=doi:10.1007%2Fs11121-016-0723-7&amp;issn=1389-4986&amp;isbn=&amp;volume=18&amp;issue=1&amp;spage=50&amp;pages=50-60&amp;date=2017&amp;title=Prevention+Science&amp;atitle=A+Meta-analysis+of+the+Effectiveness+of+Interactive+Middle+School+Cannabis+Prevention+Programs.&amp;aulast=Lize&amp;pid=%3Cauthor%3ELize+SE%3C%2Fauthor%3E%3CAN%3E27785662%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://link.springer.com/article/10.1007%2Fs11121-016-0723-7
UR  - http://download.springer.com/static/pdf/894/art%253A10.1007%252Fs11121-016-0723-7.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs11121-016-0723-7&amp;token2=exp=1489074235~acl=%2Fstatic%2Fpdf%2F894%2Fart%25253A10.1007%25252Fs11121-016-0723-7.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs11121-016-0723-7*~hmac=121a7cd2348ac652acda5e84f2efaa4099860cabdef679b25f18a53cebcbcee6
VL  - 18
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed psychiatric disorders in childhood. A wide variety of treatments have been used for the management of ADHD. We aimed to compare the efficacy and safety of pharmacological, psychological and complementary and alternative medicine interventions for the treatment of ADHD in children and adolescents. 

**METHODS AND FINDINGS: **
We performed a systematic review with network meta-analyses. Randomised controlled trials (&gt;= 3 weeks follow-up) were identified from published and unpublished sources through searches in PubMed and the Cochrane Library (up to April 7, 2016). Interventions of interest were pharmacological (stimulants, non-stimulants, antidepressants, antipsychotics, and other unlicensed drugs), psychological (behavioural, cognitive training and neurofeedback) and complementary and alternative medicine (dietary therapy, fatty acids, amino acids, minerals, herbal therapy, homeopathy, and physical activity). The primary outcomes were efficacy (treatment response) and acceptability (all-cause discontinuation). Secondary outcomes included discontinuation due to adverse events (tolerability), as well as serious adverse events and specific adverse events. Random-effects Bayesian network meta-analyses were conducted to obtain estimates as odds ratios (ORs) with 95% credibility intervals. We analysed interventions by class and individually. 190 randomised trials (52 different interventions grouped in 32 therapeutic classes) that enrolled 26114 participants with ADHD were included in complex networks. At the class level, behavioural therapy (alone or in combination with stimulants), stimulants, and non-stimulant seemed significantly more efficacious than placebo. Behavioural therapy in combination with stimulants seemed superior to stimulants or non-stimulants. Stimulants seemed superior to behavioural therapy, cognitive training and non-stimulants. Behavioural therapy, stimulants and their combination showed the best profile of acceptability. Stimulants and non-stimulants seemed well tolerated. Among medications, methylphenidate, amphetamine, atomoxetine, guanfacine and clonidine seemed significantly more efficacious than placebo. Methylphenidate and amphetamine seemed more efficacious than atomoxetine and guanfacine. Methylphenidate and clonidine seemed better accepted than placebo and atomoxetine. Most of the efficacious pharmacological treatments were associated with harms (anorexia, weight loss and insomnia), but an increased risk of serious adverse events was not observed. There is lack of evidence for cognitive training, neurofeedback, antidepressants, antipsychotics, dietary therapy, fatty acids, and other complementary and alternative medicine. Overall findings were limited by the clinical and methodological heterogeneity, small sample sizes of trials, short-term follow-up, and the absence of high-quality evidence; consequently, results should be interpreted with caution. 

**CONCLUSIONS: **
Clinical differences may exist between the pharmacological and non-pharmacological treatment used for the management of ADHD. Uncertainties about therapies and the balance between benefits, costs and potential harms should be considered before starting treatment. There is an urgent need for high-quality randomised trials of the multiple treatments for ADHD in children and adolescents. 

PROSPERO, number CRD42014015008.
AN  - 28700715
AU  - Catala-Lopez,
AU  - F.
AU  - Hutton,
AU  - B.
AU  - Nunez-Beltran,
AU  - A.
AU  - Page,
AU  - M.
AU  - J.
AU  - Ridao,
AU  - M.
AU  - Macias
AU  - Saint-Gerons,
AU  - D.
AU  - Catala,
AU  - M.
AU  - A.
AU  - Tabares-Seisdedos,
AU  - R.
AU  - Moher,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0180355
L1  - internal-pdf://3639966696/Catala-Lopez-2017-The pharmacological and non-.pdf
PY  - 2017
SP  - e0180355
TI  - The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review with network meta-analyses of randomised trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28700715
VL  - 12
ER  -
TY  - JOUR
AB  - **Purpose:**
To assess the generalizability of findings from randomized controlled trials (RCTs) evaluating emotion recognition (ER) training for children and adolescents with autism spectrum disorder (ASD). 

**Methods: **
We present a systematic review and narrative synthesis of the determinants of external validity in RCTs on ER training. Generalizability of the findings across situations, populations, settings, treatment delivery, and intervention formats was considered. 

**Results: **
We identified 13 eligible studies. Participants were predominantly boys with ASD in the normative IQ range (IQ &gt; 70), with an age span from 4 to 18 years across studies. Interventions and outcome measures were highly variable. Several studies indicated that training may improve ER, but it is still largely unknown to what extent training effects are translated to daily social life. 

**Conclusion: **
The generalizability of findings from currently available RCTs remains unclear. This underscores the importance of involving children with ASD and their caregivers in informed treatment decisions. 

Copyright &copy; 2017 Taylor &amp; Francis
AN  - 615299136
AU  - Berggren,
AU  - S.
AU  - Fletcher-Watson,
AU  - S.
AU  - Milenkovic,
AU  - N.
AU  - Marschik,
AU  - P.
AU  - B.
AU  - Bolte,
AU  - S.
AU  - Jonsson,
AU  - U.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/17518423.2017.1305004
L1  - internal-pdf://1728605325/Berggren-2017-Emotion recognition training in.pdf
PY  - 2017
SP  - 1-14
TI  - Emotion recognition training in autism spectrum disorder: A systematic review of challenges related to generalizability
UR  - http://www.tandfonline.com/loi/ipdr20
ER  -
TY  - JOUR
AB  - Universal school-based interventions that address adolescent &#039;resilience&#039; may represent a means of reducing adolescent substance use, however previous systematic reviews have not examined the effectiveness of such an intervention approach. 

A systematic review was undertaken to 1) assess whether universal school-based &#039;resilience&#039; interventions are effective in reducing the prevalence of tobacco, alcohol or illicit substance use by adolescents, and 2) describe such effectiveness per intervention characteristic subgroups. Eligible studies were peer-reviewed reports (1994-2015) of randomised controlled trials including participants aged 5-18 years that reported adolescent tobacco, alcohol or illicit substance use, and implemented a universal school-based &#039;resilience&#039; intervention (i.e. those addressing both individual (e.g. self-esteem) and environmental (e.g. school connectedness) protective factors of resilience). 

Trial effects for binary outcomes were synthesised via meta-analyses and effect sizes reported as odds ratios. Subgroup (by intervention type, prevention approach, setting, intervention duration, follow-up length) and sensitivity analyses (excluding studies at high risk of bias) were conducted. Nineteen eligible studies were identified from 16,619 records (tobacco: n = 15, alcohol: n = 17, illicit: n = 11). An overall intervention effect was found for binary measures of illicit substance use (n = 10; OR: 0.78, 95%CI: 0.6-0.93, p = 0.007,Tau&lt;sup&gt;2&lt;/sup&gt; = 0.0, I&lt;sup&gt;2&lt;/sup&gt; = 0%), but not tobacco or alcohol use. 

A similar result was found when studies assessed as high risk of bias were excluded. Overall intervention effects were evident for illicit substance use within multiple intervention characteristic subgroups, but not tobacco and alcohol. Such results support the implementation of universal school-based interventions that address &#039;resilience&#039; protective factors to reduce adolescent illicit substance use, however suggest alternate approaches are required for tobacco and alcohol use. PROSPERO registration: CRD42014004906. 

Copyright &copy; 2017 Elsevier Inc.
AN  - 616336433
AU  - Hodder,
AU  - R.
AU  - K.
AU  - Freund,
AU  - M.
AU  - Wolfenden,
AU  - L.
AU  - Bowman,
AU  - J.
AU  - Nepal,
AU  - S.
AU  - Dray,
AU  - J.
AU  - Kingsland,
AU  - M.
AU  - Yoong,
AU  - S.
AU  - L.
AU  - Wiggers,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ypmed.2017.04.003
L1  - internal-pdf://2432510013/Hodder-2017-Systematic review of universal sch.pdf
PY  - 2017
SP  - 248-268
TI  - Systematic review of universal school-based &#039;resilience&#039; interventions targeting adolescent tobacco, alcohol or illicit substance use: A meta-analysis
UR  - http://www.elsevier.com/inca/publications/store/6/2/2/9/3/4/index.htt
VL  - 100
ER  -
TY  - JOUR
AB  - To evaluate the effects of group counseling programs, cognitive behavioral therapy (CBT), and sports intervention on Internet addiction (IA), a systematic search in ten databases was performed to identify eligible studies without language restrictions up to January 2017. 

A meta-analysis and trial sequential analysis (TSA) was performed, respectively. A total of 58 randomized controlled trials (RCTs), which included 2871 participants, were incorporated into our meta-analysis. The results showed that group counseling programs, CBT, and sports intervention could significantly reduce IA levels (group counseling program: standardized mean difference (SMD), -1.37; 95% confidence interval (CI), -1.89 to -0.85; CBT: SMD, -1.88; 95% CI, -2.53 to -1.23; sports intervention: SMD, -1.70; 95% CI, -2.14 to -1.26). 

For group counseling programs, this treatment was more effective in four dimensions of IA, including time management, interpersonal and health issues, tolerance, and compulsive Internet use. For CBT, this treatment yielded a positive change in depression, anxiousness, aggressiveness, somatization, social insecurity, phobic anxiety, paranoid ideation, and psychoticism. 

For sports intervention, the significant effects were also observed in all dimensions of the IA scale. Each of group counseling programs, cognitive behavioral therapy, and sports intervention had a significant effect on IA and psychopathological symptoms. Sports intervention could improve withdrawal symptoms especially.
AN  - WOS:000423699400034
AU  - Liu,
AU  - J.
AU  - Nie,
AU  - J.
AU  - Wang,
AU  - Y.
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3390/ijerph14121470
L1  - internal-pdf://1860958693/Liu-2017-Effects of Group Counseling Programs.pdf
PY  - 2017
SP  - 17
T2  - International Journal of Environmental Research and Public Health
TI  - Effects of Group Counseling Programs, Cognitive Behavioral Therapy, and Sports Intervention on Internet Addiction in East Asia: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000423699400034
UR  - http://www.mdpi.com/1660-4601/14/12/1470/pdf
VL  - 14
ER  -
TY  - JOUR
AB  - **IMPORTANCE **
Childhood anxiety is common. Multiple treatment options are available, but existing guidelines provide inconsistent advice on which treatment to use. 

**OBJECTIVES **
To evaluate the comparative effectiveness and adverse events of cognitive behavioral therapy (CBT) and pharmacotherapy for childhood anxiety disorders. 

**DATA SOURCES **
We searched MEDLINE, EMBASE, PsycINFO, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and SciVerse Scopus from database inception through February 1, 2017. 

**STUDY SELECTION **
Randomized and nonrandomized comparative studies that enrolled children and adolescents with confirmed diagnoses of panic disorder, social anxiety disorder, specific phobias, generalized anxiety disorder, or separation anxiety and who received CBT, pharmacotherapy, or the combination. 

**DATA EXTRACTION AND SYNTHESIS **
Independent reviewers selected studies and extracted data. Random-effects meta-analysis was used to pool data. 

**MAIN OUTCOMES AND MEASURES **
Primary anxiety symptoms (measured by child, parent, or clinician), remission, response, and adverse events. 

**RESULTS **
A total of 7719 patients were included from 115 studies. Of these, 4290 (55.6%) were female, and the mean (range) age was 9.2 (5.4-16.1) years. Compared with pill placebo, selective serotonin reuptake inhibitors (SSRIs) significantly reduced primary anxiety symptoms and increased remission (relative risk, 2.04; 95% CI, 1.37-3.04) and response (relative risk, 1.96; 95% CI, 1.60-2.40). Serotonin-norepinephrine reuptake inhibitors (SNRIs) significantly reduced clinician-reported primary anxiety symptoms. Benzodiazepines and tricyclicswere not found to significantly reduce anxiety symptoms. When CBT was compared with wait-listing/no treatment, CBT significantly improved primary anxiety symptoms, remission, and response. Cognitive behavioral therapy reduced primary anxiety symptoms more than fluoxetine and improved remission more than sertraline. The combination of sertraline and CBT significantly reduced clinician-reported primary anxiety symptoms and response more than either treatment alone. Head-to-head comparisons were sparse, and network meta-analysis estimates were imprecise. Adverse events were common with medications but not with CBT and were not severe. Studies were too small or too short to assess suicidality with SSRIs or SNRIs. One trial showed a statistically nonsignificant increase in suicidal ideation with venlafaxine. Cognitive behavioral therapy was associated with fewer dropouts than pill placebo or medications. 

**CONCLUSIONS AND RELEVANCE **
Evidence supports the effectiveness of CBT and SSRIs for reducing childhood anxiety symptoms. Serotonin-norepinephrine reuptake inhibitors also appear to be effective based on less consistent evidence. Head-to-head comparisons between various medications and comparisons with CBT represent a need for research in the field.
AN  - WOS:000414516700015
AU  - Wang,
AU  - Z.
AU  - Whiteside,
AU  - S.
AU  - P.
AU  - H.
AU  - Sim,
AU  - L.
AU  - Farah,
AU  - W.
AU  - Morrow,
AU  - A.
AU  - S.
AU  - Alsawas,
AU  - M.
AU  - Barrionuevo,
AU  - P.
AU  - Tello,
AU  - M.
AU  - Asi,
AU  - N.
AU  - Beuschel,
AU  - B.
AU  - Daraz,
AU  - L.
AU  - Almasri,
AU  - J.
AU  - Zaiem,
AU  - F.
AU  - Larrea-Mantilla,
AU  - L.
AU  - Ponce,
AU  - O.
AU  - J.
AU  - LeBlanc,
AU  - A.
AU  - Prokop,
AU  - L.
AU  - J.
AU  - Murad,
AU  - M.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1001/jamapediatrics.2017.3036
L1  - internal-pdf://0952224576/Wang-2017-Comparative Effectiveness and Safety.pdf
PY  - 2017
SP  - 1049-1056
T2  - JAMA Pediatrics
TI  - Comparative Effectiveness and Safety of Cognitive Behavioral Therapy and Pharmacotherapy for Childhood Anxiety Disorders A Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000414516700015
VL  - 171
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Female genital mutilation (FGM) is associated with psychological consequences such as post-traumatic stress disorder (PSTD), depression, and anxiety disorders. Cognitive behavioral therapy (CBT), an empirically supported form of psychotherapy, may be an effective treatment for these psychological sequelae of FGM. 

**OBJECTIVES: **
To assess the effectiveness of CBT among individuals living with any type of FGM and diagnosed to have PTSD, depression, or anxiety disorders. 

**SEARCH STRATEGIES: **
CENTRAL, Medline, African Index Medicus, SCOPUS, PILOTS, POPLINE, PsycINFO, WHOLIS, LILACS, ERIC, NYAM Library, CINAHL, Web of Science were searched from inception up to August 10, 2015. 

**SELECTION CRITERIA: **
Both randomized and nonrandomized studies comparing the efficacy of CBT to other forms of interventions for PTSD, depression, or anxiety disorders in individuals with FGM, were systematically reviewed. 

**DATA COLLECTION AND ANALYSIS: **
We did not identify any studies with eligible design that addressed the objective of the review. 

**MAIN RESULTS: **
There are no included studies. 

**CONCLUSION: **
Future studies need to look beyond establishing the prevalence and correlates of FGM to conducting well-designed, randomized controlled studies or well-designed interventional observational studies for the management of the psychological consequences of women and girls living with FGM. 

Prospero registration: crd42015024458. 

Copyright &copy; 2017 International Federation of Gynecology and Obstetrics. 
The World Health Organization retains copyright and all other rights in the manuscript of this article as submitted for publication.
AD  - Adelufosi, Adegoke. Psychiatric Acute Care Unit, Thompson General Hospital, Thompson, MB, Canada. Edet, Bassey. Federal Neuro-Psychiatric Hospital, Calabar, Cross River State, Nigeria. Arikpo, Dachi. Cochrane Nigeria, Institute of Tropical Diseases Research and Prevention, University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria. Aquaisua, Ememobong. Cross River Health and Demographic Surveillance System, University of Calabar, Calabar, Nigeria. Meremikwu, Martin M. Cochrane Nigeria, Institute of Tropical Diseases Research and Prevention, University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria. Meremikwu, Martin M. Department of Pediatrics, College of Medical Sciences, University of Calabar, Calabar, Nigeria.
AN  - 28164288
AU  - Adelufosi,
AU  - A.
AU  - Edet,
AU  - B.
AU  - Arikpo,
AU  - D.
AU  - Aquaisua,
AU  - E.
AU  - Meremikwu,
AU  - M.
AU  - M.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/ijgo.12043
DP  - Ovid Technologies
J2  - Int J Gynaecol Obstet
L1  - internal-pdf://0215316961/Adelufosi-2017-Cognitive behavioral therapy fo.pdf
LA  - English
M3  - Review
N1  - Adelufosi, Adegoke Edet, Bassey Arikpo, Dachi Aquaisua, Ememobong Meremikwu, Martin M
PY  - 2017
SP  - 56-59
T2  - International Journal of Gynaecology and Obstetrics
TI  - Cognitive behavioral therapy for post-traumatic stress disorder, depression, or anxiety disorders in women and girls living with female genital mutilation: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28164288http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28164288&amp;id=doi:10.1002%2Fijgo.12043&amp;issn=0020-7292&amp;isbn=&amp;volume=136&amp;issue=1&amp;spage=56&amp;pages=56-59&amp;date=2017&amp;title=International+Journal+of+Gynaecology+%26+Obstetrics&amp;atitle=Cognitive+behavioral+therapy+for+post-traumatic+stress+disorder%2C+depression%2C+or+anxiety+disorders+in+women+and+girls+living+with+female+genital+mutilation%3A+A+systematic+review.&amp;aulast=Adelufosi&amp;pid=%3Cauthor%3EAdelufosi+A%3C%2Fauthor%3E%3CAN%3E28164288%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1002/ijgo.12043/asset/ijgo12043.pdf?v=1&amp;t=j02kq8z0&amp;s=26e3fe5043d42195211dff28ab99c794f83b8e7e
VL  - 136 Suppl 1
ER  -
TY  - JOUR
AB  - Deficiency of omega 3 fatty acids may be linked to autism spectrum disorder (ASD). Evidence about the potential therapeutic effects of supplementation of omega 3 fatty acids is lacking in ASD patients. 

We searched major electronic databases from inception to June 21, 2017, for randomized clinical trials, which compared treatment outcomes between supplementation of omega 3 fatty acids and placebo in patients with ASD. An exploratory random-effects meta-analysis of the included studies was undertaken. Six trials were included (n=194).

Meta-analysis showed that supplementation of omega 3 fatty acids improved hyperactivity (difference in means =-2.692, 95% confidence interval [CI] =-5.364 to -0.020, P=0.048, studies =4, n=109), lethargy (difference in means =-1.969, 95% CI =-3.566 to -0.372, P=0.016, studies =4, n=109), and stereotypy (difference in means =-1.071, 95% CI =-2.11 to -0.029, P=0.044, studies =4, n=109). 

No significant differences emerged between supplementation of omega 3 fatty acids and placebo in global assessment of functioning (n=169) or social responsiveness (n=97). Our preliminary meta-analysis suggests that supplementation of omega 3 fatty acids may improve hyperactivity, lethargy, and stereotypy in ASD patients. 

However, the number of studies was limited and the overall effects were small, precluding definitive conclusions. Future large-scale randomized clinical trials are needed to confirm or refute our findings. 

Copyright &copy; 2017 Cheng et al. All rights reserved.
AN  - 618724241
AU  - Cheng,
AU  - Y.
AU  - S.
AU  - Tseng,
AU  - P.
AU  - T.
AU  - Chen,
AU  - Y.
AU  - W.
AU  - Stubbs,
AU  - B.
AU  - Yang,
AU  - W.
AU  - C.
AU  - Chen,
AU  - T.
AU  - Y.
AU  - Wu,
AU  - C.
AU  - K.
AU  - Lin,
AU  - P.
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2147/NDT.S147305
L1  - internal-pdf://3840516482/Cheng-2017-Supplementation of omega 3 fatty ac.pdf
PY  - 2017
SP  - 2531-2543
TI  - Supplementation of omega 3 fatty acids may improve hyperactivity, lethargy, and stereotypy in children with autism spectrum disorders: A meta-analysis of randomized controlled trials
UR  - http://www.dovepress.com/neuropsychiatric-disease-and-treatment-journal
VL  - 13
ER  -
TY  - JOUR
AB  - Research with adults has consistently demonstrated that the use of regular client feedback in psychological services can improve outcomes. However, there appear to be fewer studies with youth. 

The purpose of the current review was to explore/assess (1) current developments in research on the use of feedback-informed approaches in mental health interventions or services for youth 10-19 years of age; (2) the efficacy of client feedback in youth treatment settings; and (3) consider future directions for research. A total of 12 studies were included in this review, comprising a meta-analysis (n = 9) and a qualitative review (n = 3). Most studies assessed the benefits of a feedback framework in terms of symptom severity, functioning levels and/or goal attainments in therapy (i.e., ratings on the feedback-informed tools). 

The Hedges&#039;s g indexes of 0.20 (for independent-groups trials), 0.32 (single-group trials) and 0.28 (for all trials) suggest that the collection and application of continuous feedback from youth clients throughout the course of the interventions/services can boost and produce beneficial outcomes for the youth, while noting the feedback effect to be in the small range. 

Based on these initial findings, implications for future research and clinical practice are discussed, including considering fruitful research directions. 

Copyright &copy; 2017 Elsevier Ltd
AN  - 616033046
AU  - Tam,
AU  - H.
AU  - E.
AU  - Ronan,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2017.04.005
L1  - internal-pdf://4043590175/Tam-2017-The application of a feedback-informe.pdf
PY  - 2017
SP  - 41-55
TI  - The application of a feedback-informed approach in psychological service with youth: Systematic review and meta-analysis
UR  - http://www.elsevier.com/locate/clinpsychrev
VL  - 55
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Parenting programs aim to reduce children&#039;s conduct problems through improvement of family dynamics. To date, research on the precise benefits and possible harms of parenting programs on family well-being has been unsystematic and likely to be subject to selective outcome reporting and publication bias. Better understanding of program benefits and harms requires full disclosure by researchers of all included measures, and large enough numbers of participants to be able to detect small effects and estimate them precisely.

METHODS: 
We obtained individual participant data for 14 of 15 randomized controlled trials on the Incredible Years parenting program in Europe (total N = 1,799). We used multilevel modeling to estimate program effects on 13 parent-reported outcomes, including parenting practices, children&#039;s mental health, and parental mental health.

RESULTS: 
Parental use of praise, corporal punishment, threats, and shouting improved, while parental use of tangible rewards, monitoring, or laxness did not. Children&#039;s conduct problems and attention deficit hyperactivity disorder (ADHD) symptoms improved, while emotional problems did not. Parental mental health (depressive symptoms, self-efficacy, and stress) did not improve. There was no evidence of harmful effects.

CONCLUSIONS: 
The Incredible Years parenting program improves the aspects of family well-being that it is primarily designed to improve: parenting and children&#039;s conduct problems. It also improves parent-reported ADHD symptoms in children. Wider benefits are limited: the program does not improve children&#039;s emotional problems or parental mental health. There are no signs of harm on any of the target outcomes.
AD  - Leijten, Patty. University of Oxford, Oxford, UK.Leijten, Patty. University of Amsterdam, Amsterdam, The Netherlands.Gardner, Frances. University of Oxford, Oxford, UK.Landau, Sabine. King&#039;s College London, London, UK.Harris, Victoria. King&#039;s College London, London, UK.Mann, Joanna. University of Oxford, Oxford, UK.Hutchings, Judy. Bangor University, Bangor, UK.Beecham, Jennifer. London School of Economics, London, UK.Beecham, Jennifer. Kent University, Canterbury, UK.Bonin, Eva-Maria. London School of Economics, London, UK.Bonin, Eva-Maria. Kent University, Canterbury, UK.Scott, Stephen. King&#039;s College London, London, UK.
AN  - 28696032
AU  - Leijten,
AU  - P.
AU  - Gardner,
AU  - F.
AU  - Landau,
AU  - S.
AU  - Harris,
AU  - V.
AU  - Mann,
AU  - J.
AU  - Hutchings,
AU  - J.
AU  - Beecham,
AU  - J.
AU  - Bonin,
AU  - E.
AU  - M.
AU  - Scott,
AU  - S.
DA  - Jul 11
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcpp.12781
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
L1  - internal-pdf://2367455625/leijten2018.pdf
LA  - English
M3  - Review
N1  - Leijten, PattyGardner, FrancesLandau, SabineHarris, VictoriaMann, JoannaHutchings, JudyBeecham, JenniferBonin, Eva-MariaScott, StephenUsing Smart Source ParsingJul
PY  - 2017
SP  - 11
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Research Review: Harnessing the power of individual participant data in a meta-analysis of the benefits and harms of the Incredible Years parenting program
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28696032
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28696032&amp;id=doi:10.1111%2Fjcpp.12781&amp;issn=0021-9630&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2017&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Research+Review%3A+Harnessing+the+power+of+individual+participant+data+in+a+meta-analysis+of+the+benefits+and+harms+of+the+Incredible+Years+parenting+program.&amp;aulast=Leijten&amp;pid=%3Cauthor%3ELeijten+P%3C%2Fauthor%3E%3CAN%3E28696032%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 11
ER  -
TY  - JOUR
AB  - This article presents a review to evaluate potential cardiovascular effects of these treatments, the authors conducted a systematic review and meta-analysis of the effects of methylphenidate (MPH), amphetamines (AMP), and atomoxetine (ATX) on diastolic and systolic blood pressure (DBP, SBP) and heart rate (HR) in children and adolescents with attention deficit/hyperactivity disorder (ADHD). 

The authors conducted systematic searches in electronic databases (PsychINFO, EMBASE and Medline) to identify published trials which involved individuals who were (i) diagnosed with ADHD and were aged between 0-18 years; (ii) treated with MPH, AMP or ATX and (iii ) had their DBP and SBP and/or HR measured at baseline (pre) and the endpoint (post) of the study treatment. Eighteen clinical trials met the inclusion criteria (10 for MPH, 5 for AMP, and 7 for ATX) with data from 5837 participants (80.7% boys) and average duration of 28.7 weeks (range 4-96 weeks). 

Statistically significant pre-post increases of SBP, DBP and HR were associated with AMP and ATX treatment in children and adolescents with ADHD, while MPH treatment had a statistically significant effect only on SBP in these patients. These increases may be clinically significant for a significant minority of individuals that experience larger increases. 

Since increased BP and HR in general are considered risk factors for cardiovascular morbidity and mortality during adult life, pediatric patients using ADHD medication should be monitored closely and regularly for HR and BP. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-10476-004
AU  - Hennissen,
AU  - L.
AU  - Bakker,
AU  - J.
AU  - Banaschewski,
AU  - T.
AU  - Carucci,
AU  - S.
AU  - Coghill,
AU  - D.
AU  - Danckaerts,
AU  - M.
AU  - Dittmann,
AU  - R.
AU  - W.
AU  - Hollis,
AU  - C.
AU  - Kovshoff,
AU  - H.
AU  - McCarthy,
AU  - S.
AU  - Nagy,
AU  - P.
AU  - Sonuga-Barke,
AU  - E.
AU  - Wong,
AU  - I.
AU  - C.
AU  - Zuddas,
AU  - A.
AU  - Rosenthal,
AU  - E.
AU  - Buitelaar,
AU  - J.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s40263-017-0410-7
L1  - internal-pdf://2535021422/Hennissen-2017-Cardiovascular effects of stimu.pdf
PY  - 2017
SP  - 199-215
T2  - CNS Drugs
TI  - Cardiovascular effects of stimulant and non-stimulant medication for children and adolescents with ADHD: A systematic review and meta-analysis of trials of methylphenidate, amphetamines and atomoxetine
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-10476-004
VL  - 31
ER  -
TY  - JOUR
AB  - The role of omega-3 polyunsaturated fatty acids (omega-3 or n-3 PUFAs) in the pathogenesis and treatment of children and adolescents with attention deficit hyperactivity disorder (ADHD) is unclear. 

A systematic review followed by meta-analysis was conducted on: (1) randomized controlled trials (RCTs) assessing the effects of n-3 PUFAs on clinical symptoms and cognition in children and adolescent with ADHD; and (2) case-control studies assessing the levels of n-3 PUFAs in blood and buccal tissues of children and adolescents with ADHD. 

In seven RCTs, totalling n=534 randomised youth with ADHD, n-3 PUFAs supplementation improves ADHD clinical symptom scores (g=0.38, p&lt;0.0001); and in three RCTs, totalling n=214 randomised youth with ADHD, n-3 PUFAs supplementation improves cognitive measures associated with attention (g=1.09, p=0.001). Moreover, children and adolescents with ADHD have lower levels of DHA (seven studies, n=412, g=-0.76, p=0.0002), EPA (seven studies, n=468, g=-0.38, p=0.0008), and total n-3 PUFAs (six studies, n=396, g=-0.58, p=0.0001). 

In summary, there is evidence that n-3 PUFAs supplementation monotherapy improves clinical symptoms and cognitive performances in children and adolescents with ADHD, and that these youth have a deficiency in n-3 PUFAs levels. 

Our findings provide further support to the rationale for using n-3 PUFAs as a treatment option for ADHD.
AN  - 28741625
AU  - Chang,
AU  - J.
AU  - C.
AU  - Su,
AU  - K.
AU  - P.
AU  - Mondelli,
AU  - V.
AU  - Pariante,
AU  - C.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1038/npp.2017.160
L1  - internal-pdf://2814584035/Chang-2017-Omega-3 Polyunsaturated Fatty Acids.pdf
PY  - 2017
SP  - 25
TI  - Omega-3 Polyunsaturated Fatty Acids in Youths with Attention Deficit Hyperactivity Disorder (ADHD): A Systematic Review and Meta-Analysis of Clinical Trials and Biological Studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28741625
VL  - 25
ER  -
TY  - JOUR
AB  - Socioeconomic status is a major predictor of educational achievement. This systematic review and meta-analysis seeks to identify effective academic interventions for elementary and middle school students with low socioeconomic status. 

Included studies have used a treatment-control group design, were performed in OECD and EU countries, and measured achievement by standardized tests in mathematics or reading. The analysis included 101 studies performed during 2000 to 2014, 76% of which were randomized controlled trials. 

The effect sizes (ES) of many interventions indicate that it is possible to substantially improve educational achievement for the target group. Intervention components such as tutoring (ES = 0.36), feedback and progress monitoring (ES = 0.32), and cooperative learning (ES = 0.22) have average ES that are educationally important, statistically significant, and robust. 

There is also substantial variation in effect sizes, within and between components, which cannot be fully explained by observable study characteristics. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-11778-001
AU  - Dietrichson,
AU  - J.
AU  - Bog,
AU  - M.
AU  - Filges,
AU  - T.
AU  - Jorgensen,
AU  - A.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3102/0034654316687036
L1  - internal-pdf://0567585352/Dietrichson-2017-Academic interventions for el.pdf
PY  - 2017
SP  - 243-282
T2  - Review of Educational Research
TI  - Academic interventions for elementary and middle school students with low socioeconomic status: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2017-11778-001
UR  - http://journals.sagepub.com/doi/10.3102/0034654316687036
UR  - http://journals.sagepub.com/doi/pdf/10.3102/0034654316687036
VL  - 87
ER  -
TY  - GEN
AB  - **Background:** 
Mass media interventions can be used as a way of delivering preventive health messages. They have the potential to reach and modify the knowledge, attitudes and behaviour of a large proportion of the community.

**Objectives:** 
To assess the effects of mass media interventions on preventing smoking in young people, and whether it can reduce smoking uptake among youth (under 25 years), improve smoking attitudes, intentions and knowledge, improve self-efficacy/self-esteem, and improve perceptions about smoking, including the choice to follow positive role models.

**Search methods:** 
We searched the Cochrane Tobacco Addiction Group Specialized Register, with additional searches of MEDLINE and Embase in June 2016. This is an update of a review first published in 1998.

**Selection criteria:** 
Randomized trials, controlled trials without randomization and interrupted time-series studies that assessed the effect of mass media campaigns (defined as channels of communication such as television, radio, newspapers, social media, billboards, posters, leaflets or booklets intended to reach large numbers of people and which are not dependent on person-to-person contact) in influencing the smoking behaviour (either objective or self-reported) of young people under the age of 25 years. We define smoking behaviour as the presence or absence of tobacco smoking or other tobacco use, or both, and the frequency of tobacco use. Eligible comparators included education or no intervention.

**Data collection and analysis:** 
Two review authors independently extracted information relating to the characteristics and the content of media interventions, participants, outcomes, methods of the study and risks of bias. We combined studies using qualitative narrative synthesis. We assessed the risks of bias for each study using the Cochrane &#039;Risk of bias&#039; tool, alongside additional domains to account for the nature of the intervention. We assessed the quality of evidence contributing to outcomes using GRADE.

**Main results:** 
We identified eight eligible studies reporting information about mass media smoking campaigns, one of which is new for this update. Seven of the studies used a controlled trial design and one an interrupted time-series analysis. Risks of bias were high across all included studies and there was considerable heterogeneity in study design, intervention and population being assessed.Three studies (n = 17,385), one of which compared a mass media intervention to no intervention and two of which evaluated mass media interventions as adjuncts to school-based interventions, found that the mass media interventions reduced the smoking behaviour of young people. The remaining five studies (n = 72,740) did not detect a significant effect on smoking behaviour. These included three studies comparing a mass media intervention to no intervention, one study evaluating a mass media intervention as an adjunct to a school-based intervention, and one interrupted time-series study of a social media intervention. The three campaigns which found a significant effect described their theoretical basis, used formative research in designing the campaign messages, and used message broadcast of reasonable intensity over extensive periods of time. However, some of the campaigns which did not detect an effect also exhibited these characteristics. Effective campaigns tended to last longer (minimum 3 years) and were more intense (more contact time) for both school-based lessons (minimum eight lessons per grade) and media spots (minimum four weeks&#039; duration across multiple media channels with between 167 and 350 TV and radio spots). Implementation of combined school-based components (e.g. school posters) and the use of repetitive media messages delivered by multiple channels (e.g. newspapers, radio, television) appeared to contribute to successful campaigns.

**Authors&#039; conclusions:** 
Certainty about the effects of mass media campaigns on smoking behaviour in youth is very low, due to inconsistency between studies in both design and results, and due to methodological issues amongst th included studies. It would therefore be unwise to offer firm conclusions based on the evidence in this review. Methodologically rigorous studies investigating the effect of social media and novel forms of technology as part of tobacco prevention campaigns for youth are needed.
AN  - CD001006
AU  - Carson,
AU  - K.
AU  - V.
AU  - Ameer,
AU  - F.
AU  - Sayehmiri,
AU  - K.
AU  - Hnin,
AU  - K.
AU  - van
AU  - Agteren,
AU  - J.
AU  - Sayehmiri,
AU  - F.
AU  - Brinn,
AU  - M.
AU  - Esterman,
AU  - A.
AU  - Chang,
AU  - A.
AU  - Smith,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD001006.pub3
KW  - Health Education
KW  - Mass Media
KW  - Age Factors
KW  - Health Promotion
KW  - Smoking [prevention &amp; control]
KW  - Adolescent[checkword]
KW  - Humans[checkword]
KW  - Young Adult[checkword]
L1  - internal-pdf://2300644442/Carson-2017-Mass media interventions for preve.pdf
PY  - 2017
T2  - Cochrane Database of Systematic Reviews
TI  - Mass media interventions for preventing smoking in young people
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001006.pub3/abstract
UR  - http://onlinelibrary.wiley.com/store/10.1002/14651858.CD001006.pub3/asset/CD001006.pdf?v=1&amp;t=j82wqetn&amp;s=9fc36a1f31c6078b19e5f39cf2f20d7f52bed3cf
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Coping Cat (CC), a generic cognitive-behavioral intervention for anxiety disorders in children and young people, is recommended in the United Kingdom for social anxiety disorder (SAD), generalized anxiety disorder, separation anxiety (SA), and specific phobias (SP), with disorder-specific approaches generally favored in treatment of anxiety disorders in adults. 

**OBJECTIVES: **
To compare CC with disorder-specific cognitive-behavioral therapy (CBT) interventions based on anxiety-related treatment outcomes. 

**STUDY SELECTION: **
Primary research articles describing treatment of children and young people aged 7-17 for SAD, generalized anxiety disorder, SA, and SP, using CC or disorder-specific CBT. 

**RESULTS: **
Ten studies implemented CC and four implemented disorder-specific CBT. One study compared CC with a disorder-specific approach. There was a lack of data to support use of CC in treatment of SPs. However, CC was equally effective as disorder-specific treatments for SA and SAD. 

**CONCLUSIONS:** 
A lack of data exists for disorder-specific CBT interventions compared to CC. 

Copyright &copy; 2017 Wiley Periodicals, Inc.
AN  - 28513061
AU  - Oldham-Cooper,
AU  - R.
AU  - Loades,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jcap.12165
L1  - internal-pdf://1667671462/Oldham-Cooper-2017-Disorder-specific versus ge.pdf
PY  - 2017
SP  - 6-17
TI  - Disorder-specific versus generic cognitive-behavioral treatment of anxiety disorders in children and young people: a systematic narrative review of evidence for the effectiveness of disorder-specific CBT compared with the disorder-generic treatment, Coping Cat
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28513061
VL  - 30
ER  -
TY  - JOUR
AB  - **AIM: **
To provide a systematic overview of longitudinal studies on different smoking-specific parenting practices (i.e., perceived parental norms and influences, smoking-specific monitoring, availability of cigarettes at home, household smoking rules, non-smoking agreements, smoking-specific communication, and parental reactions) as useful tools in the prevention of youth smoking. 

**METHOD: **
MEDLINE and PsychINFO search identified 986 studies published from 1990 to December 2016. Two independent researchers identified eligible studies. Study quality was assessed using Newcastle Ottawa Scale (NOS). 

**RESULTS: **
The systematic search resulted in 1 to 14 longitudinal studies per parenting practice. Studies scored between 4 and 9 on the NOS, indicating an overall moderate quality. The results of complete smoking house rules showed a preventive effect on smoking onset. Furthermore, availability of cigarettes, frequency and quality of communication, parental reaction (i.e., conflict engagement) and norms showed significant and non-significant effects. Significant results were in line with expectations: availability of cigarettes and frequent communication about smoking predicted smoking, whereas a high quality of communication, negative reactions or punishments and setting norms by parents showed a preventive effect. No effects were found for non-smoking agreements. The number of studies was too limited to draw conclusions about other parenting strategies. More research on (1) reliable and valid instruments, (2) other stages of smoking in addition to onset, and (3) potential moderators and mediators is warranted. 

**CONCLUSION: **
While evidence supports the effectiveness of smoking-specific parenting, further research is required. 

Copyright &copy; 2017 Elsevier Ltd. All rights reserved.
AN  - 28237717
AU  - Hiemstra,
AU  - M.
AU  - de
AU  - Leeuw,
AU  - R.
AU  - N.
AU  - Engels,
AU  - R.
AU  - C.
AU  - Otten,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.addbeh.2017.02.003
L1  - internal-pdf://4169399919/Hiemstra-2017-What parents can do to keep thei.pdf
PY  - 2017
SP  - 107-128
TI  - What parents can do to keep their children from smoking: A systematic review on smoking-specific parenting strategies and smoking onset
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28237717
VL  - 70
ER  -
TY  - JOUR
AB  - **Background:**
Effective treatments for the core symptoms of autism spectrum disorder (ASD) are still lacking.

**Objective:**
We aimed to update the data on the effectiveness of omega-3 (n-3) fatty acid (FA) supplementation as a treatment for ASD.

**Methods:**
The Cochrane Library, MEDLINE, and EMBASE databases were systematically searched up until August 2016 with no language restrictions for randomized controlled trials (RCTs) comparing omega-3 FA supplementation with placebo or with no supplementation. Participants were children diagnosed with ASD. All functional outcome measures reported were considered. For dichotomous outcomes, the results for individual studies and pooled statistics were reported as RRs. Mean differences (MDs) were calculated for continuous outcomes.

**Results:**
Five RCTs (183 participants) were included. With 4 exceptions, there were no statistically significant differences in ASD symptoms between groups measured by validated scales. Among studies that used the Aberrant Behavior Checklist, parents&#039; ratings indicated significant improvement in lethargy symptoms in the omega-3 FA group compared with the placebo group (2 RCTs) (pooled MD: 1.98; 95% CI: 0.32, 3.63). Among studies that used the Behavioral Assessment System for Children, parents&#039; ratings indicated significant worsening of both externalizing behavior (2 RCTs) (pooled MD: -6.22; 95% CI: -10.9, -1.59) and social skills (1 RCT) (MD: -7; 95% CI: -13.62, -0.38) in the omega-3 FA group compared with the placebo group. One RCT reported a significant improvement in the omega-3 FA group for the daily-living component of the Vineland Adaptive Behavior Scale (MD: 6.2; 95% CI: 0.37, 12.03). Adverse effects were similar in both groups.

**Conclusions:** 
Because of the limited number of included studies and small sample sizes, no firm conclusions can be drawn. However, the limited data currently available suggest that omega-3 FA supplementation does not enhance the performance of children with ASD. 

Copyright &copy; 2017 American Society for Nutrition.
AN  - 28077731
AU  - Horvath,
AU  - A.
AU  - Lukasik,
AU  - J.
AU  - Szajewska,
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3945/jn.116.242354
L1  - internal-pdf://0082655955/Horvath-2017-omega-3 Fatty Acid Supplementatio.pdf
PY  - 2017
SP  - 367-376
TI  - omega-3 Fatty Acid Supplementation Does Not Affect Autism Spectrum Disorder in Children: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28077731
VL  - 147
ER  -
TY  - JOUR
AB  - Objective: 
Building self-esteem in overweight adolescents is key to long-term weight management; yet, self-esteem is rarely a key outcome of adolescent weight management interventions. This systematic review investigates the impact of multicomponent weight management interventions on self-esteem in overweight and obese adolescents.

Method: 
Six databases were searched in December 2014. Eligible studies met the following criteria: (1) randomized controlled trial, (2) overweight or obese participants, (3) adolescents (10-19 years), (4) multicomponent weight management intervention, (5) reported self-esteem and weight changes. 

Results: 
Thirteen studies with 1,157 overweight or obese adolescents, aged 10-19 years, were included. Meta-analyses showed no significant change in self-esteem (0.27 [-0.04, 0.59]), but body mass index z-score reduced following intervention (-0.17 [-0.22, -0.11]). 

Conclusion: 
The lack of change in self-esteem suggests weight loss alone is insufficient to improve self-esteem. Multicomponent weight management interventions require a specific focus on self-esteem to improve this outcome in overweight and obese adolescents. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-44675-007
AU  - Murray,
AU  - M.
AU  - Dordevic,
AU  - A.
AU  - L.
AU  - Bonham,
AU  - M.
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1093/jpepsy/jsw101
L1  - internal-pdf://2821002913/Murray-2017-Systematic review and meta-analysi.pdf
PY  - 2017
SP  - 379-394
TI  - Systematic review and meta-analysis: The impact of multicomponent weight management interventions on self-esteem in overweight and obese adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-44675-007
VL  - 42
ER  -
TY  - JOUR
AB  - The cognitive development of children of adolescent mothers has often been considered to be at risk. The purpose of this meta-analysis is to examine whether early intervention could help foster more positive cognitive development in the 0- to 4-year-old children of adolescent mothers. Twenty-two studies were reviewed, involving 29 different intervention strategies and 3577 participants. 

An overall effect size (corrected for publication bias) of d = .24 was found (95% CI .11, .36). Intervention strategies that focused specifically on the quality of parent-child interaction (d = .89; 95%CI .36, 1.43) or that included parent-child interaction as an important target of intervention (d = .53; 95%CI .34, .73) yielded greater effect sizes than those that emphasized maternal support and education (d = .23; 95% CI .12, .34). Intervention that was delivered in groups (d = .56; 95% CI .36, .74) yielded greater effectiveness than dyadic intervention (d = .27; 95% CI .14, .39). Intervention delivered by trained professionals (d = .39; 95% CI .22, .56) was more effective than that delivered by paraprofessionals (d = .20; 95% CI -.02, .61). 

Older studies (slope = -.015) and those that involved smaller numbers of participants (slope = -.0008) also yielded greater effect sizes. There was also a marginal tendency for shorter intervention strategies (slope = -.002), and those that involved younger children (slope = -.005) and mothers (slope = -.074) to show greater effects. 

Discussion focuses on the developmental and practical implications of these results. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2016-55176-001
AU  - Baudry,
AU  - C.
AU  - Tarabulsy,
AU  - G.
AU  - M.
AU  - Atkinson,
AU  - L.
AU  - Pearson,
AU  - J.
AU  - St-Pierre,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s11121-016-0731-7
L1  - internal-pdf://2857868450/Baudry-2017-Intervention with adolescent mothe.pdf
PY  - 2017
SP  - 116-130
TI  - Intervention with adolescent mother-child dyads and cognitive development in early childhood: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-55176-001
VL  - 18
ER  -
TY  - JOUR
AB  - **BACKGROUND **
Tools of the Mind (Tools) is an early childhood education curriculum that aims to simultaneously promote children&rsquo;s self-regulation and academic skills. Given the increasing focus on self-regulation and other social-emotional skills in educational contexts, Tools has become increasingly implemented in classrooms around the United States, Canada, and Chile. Despite its growing popularity, Tools&rsquo; evidence base remains mixed. 

**OBJECTIVES **
The aim of this review is to synthesize the evidence on the effectiveness of the Tools program in promoting children&rsquo;s self-regulation and academic skills. 

**SEARCH METHODS **
The systematic search was conducted from October 21 through December 3, 2016. The search yielded 176 titles and abstracts, 25 of them deemed potentially relevant. After full-text screening, 14 reports from six studies were eligible for inclusion. 

**SELECTION CRITERIA **
In order to be included, a study must have had one or more quantitative effect sizes regarding Tools&rsquo; effectiveness in the self-regulatory or academic domains. Moreover, the study must have employed statistical mechanisms to control for potential confounds. Studies that compared Tools with a business-as-usual or another intervention were eligible for inclusion, whereas studies that did not pertain to the Tools curriculum were excluded. The reports, whether published or unpublished, could come from any national context, language, student population, or time period as long as the conditions outlined above were met. 

**DATA COLLECTION AND ANALYSIS **
All included studies classified as randomized controlled trials, though, again, quasiexperimental studies had been eligible for inclusion. Each included study yielded effect sizes in the form of standardized mean differences. The outcomes of interest included assessorreported self-regulation skills (e.g., teachers or parents rating children&rsquo;s self-regulation), task-based self-regulation skills (e.g., children performing a self-regulation task on a computer and receiving a score), literacy skills, and math skills. All effect sizes were interpreted as Tools&rsquo; effect relative to other business-as-usual programs or other interventions. 

**RESULTS **
The evidence indicated statistically significant benefits for Tools children on the math pooled effect size. The other pooled effect sizes for self-regulation and literacy favored Tools but did not reach statistical significance. 

**AUTHORS&rsquo; CONCLUSIONS **
The results indicate positive yet small effects for the Tools program. Three of the four pooled effect sizes did not reach statistical significance, but all four pooled effect sizes favored Tools. The small number of included studies reduced power, which could explain the lack of statistical significance across three of the four outcome measures. By contrast, it is also possible that Tools either does not substantially influence children&rsquo;s self-regulation or that the influence is too small to be detected with the current evidence base.
AU  - Baron,
AU  - A.
AU  - Evangelou,
AU  - M.
AU  - Malmberg,
AU  - L-E.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.campbellcollaboration.org/media/k2/attachments/0269_ECG_Baron_Curriculum_systematic_review.pdf
PY  - 2017
T2  - Campbell Systematic Reviews
TI  - The Tools of the Mind curriculum for improving selfregulation in early childhood: a systematic revie
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Perform a systematic review of the available literature regarding the effectiveness of exercise interventions on children with any type of social, emotional, or behavioral disability (SEBD), with attention to a range of physiological, behavioral, and mood outcomes. 

**METHODS: **
Six databases were searched using a systematic methodology. References of included studies, as well as relevant reviews, were also examined. The review was limited to studies published since 2000 reporting a quantitative analysis of the effects of a physical activity (PA) intervention on at least 1 behavioral, psychological, or cognitive outcome in children aged 21 and under, diagnosed with a SEBD. Only studies with a control group were included. 

**RESULTS: **
We identified 24 eligible studies. Studies varied in design, participant characteristics, and intervention characteristics (single-bout vs repeated exposure, duration, intensity level, mode of exercise). Of the 20 behavioral outcome assessments, there was 1 negative finding, 12 null findings, 5 positive findings, and 2 mixed findings. For the 25 executive functioning outcome assessments, there were 5 null findings, 18 positive findings, and 2 mixed findings. For the remaining outcome domains, 1 of 2 studies looking at academic performance, 3 of 6 studies looking at objective neurological measures, and 1 of 3 studies looking at affect outcomes found positive results. All other results were null or mixed. 

**CONCLUSION: **
Although additional research is warranted to further understand the mechanisms by which PA affects behavioral and cognitive outcome measures in children with SEBDs, PA offers a safe and alternative form of treatment for this population.
AN  - 28692579
AU  - Ash,
AU  - T.
AU  - Bowling,
AU  - A.
AU  - Davison,
AU  - K.
AU  - Garcia,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/DBP.0000000000000452
L1  - internal-pdf://0406048753/Ash-2017-Physical Activity Interventions for C.pdf
PY  - 2017
SP  - 29
TI  - Physical Activity Interventions for Children with Social, Emotional, and Behavioral Disabilities-A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28692579
VL  - 29
ER  -
TY  - JOUR
AB  - **Objective: **
To examine the effect of universal, school-based, resilience-focused interventions on mental health problems in children and adolescents. 

**Method: **
Eligible studies were randomized controlled trials (RCTs) of universal, school-based interventions that included strategies to strengthen a minimum of 3 internal resilience protective factors, and included an outcome measure of mental health problems in children and adolescents aged 5 to 18 years. Six databases were searched from 1995 to 2015. Results were pooled in meta-analyses by mental health outcome (anxiety symptoms, depressive symptoms, hyperactivity, conduct problems, internalizing problems, externalizing problems, and general psychological distress), for all trials (5-18 years). Subgroup analyses were conducted by age (child: 5-10 years; adolescent: 11-18 years), length of follow-up (short: post-&lt;=12 months; long: &gt;12 months), and gender (narrative). 

**Results: **
A total of 57 included trials were identified from 5,984 records, with 49 contributing to meta-analyses. For all trials, resilience-focused interventions were effective relative to a control in reducing 4 of 7 outcomes: depressive symptoms, internalizing problems, externalizing problems, and general psychological distress. For child trials (meta-analyses for 6 outcomes), interventions were effective for anxiety symptoms and general psychological distress. For adolescent trials (meta-analyses for 5 outcomes), interventions were effective for internalizing problems. For short-term follow-up, interventions were effective for 2 of 7 outcomes: depressive symptoms and anxiety symptoms. For long-term follow-up (meta-analyses for 5 outcomes), interventions were effective for internalizing problems. 

**Conclusion: **
The findings may suggest most promise for using universal resilience-focused interventions at least for short-term reductions in depressive and anxiety symptoms for children and adolescents, particularly if a cognitive-behavioral therapy-based approach is used. The limited number of trials providing data amenable for meta-analysis for some outcomes and subgroups, the variability of interventions, study quality, and bias mean that it is not possible to draw more specific conclusions. Identifying what intervention qualities (such as number and type of protective factor) achieve the greatest positive effect per mental health problem outcome remains an important area for future research. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-43986-009
AU  - Dray,
AU  - J.
AU  - Bowman,
AU  - J.
AU  - Campbell,
AU  - E.
AU  - Freund,
AU  - M.
AU  - Wolfenden,
AU  - L.
AU  - Hodder,
AU  - R.
AU  - K.
AU  - McElwaine,
AU  - K.
AU  - Tremain,
AU  - D.
AU  - Bartlem,
AU  - K.
AU  - Bailey,
AU  - J.
AU  - Small,
AU  - T.
AU  - Palazzi,
AU  - K.
AU  - Oldmeadow,
AU  - C.
AU  - Wiggers,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2017.07.780
L1  - internal-pdf://3396006277/Dray-2017-Systematic review of universal resil.pdf
PY  - 2017
SP  - 813-824
TI  - Systematic review of universal resilience-focused interventions targeting child and adolescent mental health in the school setting
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-43986-009
VL  - 56
ER  -
TY  - JOUR
AB  - **Innledning** 
I følge Folkehelseinstituttet har til enhver tid &eacute;n av 20 norske barn og unge så alvorlige depressive symptomer at de kan diagnostiseres med depresjon. Depresjon kan gi økt risiko for rusmisbruk og selvskading. Symptomene på depresjon varierer, men kan være vedvarende følelse av nedstemthet, verdiløshet, selvmordstanker, manglende livsglede eller manglende energi. Psykologisk terapi er gjerne førstevalget i behandlingen av barn og unge med depresjonssymptomer eller depresjon. I en nylig publisert systematisk oversikt ble det ikke funnet klar dokumentasjon for at psykologisk terapi, blant annet kognitiv atferdsterapi hadde effekt for barn under 12 år med depresjon. Det tilbys flere terapiformer som for eksempel kognitiv atferdsterapi, mentaliseringsbasert terapi, adferdsterapi, interpersonlig terapi, løsningsfokusert terapi og psykoedukativ terapi. Antidepressive medikamenter tilbys også til barn og unge. I de senere årene har selektive serotoninreopptakshemmere (SSRI) og andre nyere antidepressive medikamenter blitt brukt i behandling av depresjon hos noen barn og unge. Totalt bruker omtrent to av 100 barn og unge (opp til 19 år) antidepressiva. I en nylig publisert nettverksmetaanalyse om effekt av flere ulike antidepressive medikamenter for barn med depresjon konkluderes det med at fluoxetin trolig har best effekt. Vi er bedt om å oppdatere analyser for to spørsmål fra en Cochrane‐oversikt publisert i 2014 om effekten av psykologisk terapi sammenlignet med antidepressive medikamenter alene eller i kombinasjon med psykologisk terapi for barn og unge med depresjon. Cochrane‐oversikten hadde inkludert to studier om disse to analysene. 

**Metode** 
Vi brukte søkestrategien fra Cochrane‐forfatterne og søkte i september 2016 i CENTRAL. Vi søkte etter randomiserte kontrollerte studier publisert fra og med 2013. Vi hadde følgende inklusjonskriterier: Populasjon: Barn med depresjon Tiltak: Psykologisk terapi Sammenligning: Antidepressive medikamenter alene, eller antidepressive medikamenter kombinert med psykologisk terapi Utfall: Depresjon, remisjon, frafall, selvmordstanker og fungering. To forfattere gikk, uavhengig av hverandre, gjennom titler og sammendrag. De samme to personene vurderte artiklene i fulltekst med tanke på inklusjon eller eksklusjon. En prosjektmedarbeider trakk ut data fra de inkluderte artiklene og en annen sjekket tal‐ lene. Der data kunne slås sammen med eksisterende metaanalyser gjorde vi det med samme metode som Cochrane‐forfatterne. Vi baserte oss på Cochrane‐oversikten når det gjaldt å vurdere risikoen for systematiske feil for allerede inkluderte studier og gjorde ny vurdering av nye studier. Vi har brukt Grading of Recommendations Assess‐ ment, Development and Evaluation (GRADE) for å vurdere tilliten til dokumentasjonen for utfallene. 

**Resultat** 
Vi gikk gjennom 866 referanser etter søk. Vi leste ti artikler i fulltekst. Ni av disse ble ekskludert fordi de enten var protokoll til pågående studier, eller de studerte voksne, eller det var ikke randomiserte kontrollerte studier. Våre funn baserer seg på tre stu‐ dier fra Romania, USA og Australia med totalt 481 barn mellom 11 og 18 år. Studiene var publisert i 2004, 2006 og 2015. De to eldste studiene var mer i Cochrane‐oversikten, mens studien fra 2015 er ny. Barn som var suicidale ble ekskludert, og de aller fleste deltagerne hadde også andre psykiatriske diagnoser som angstlidelser. De tre inkluderte studiene undersøkte effekten av kognitiv atferdsterapi. Barna i Romania og Australia fikk sertralin, mens i USA fikk de fluoxetin. Den rumenske studien har bare målt utfall ved behandlingsslutt. De andre hadde oppfølgingsdata for opptil ett år etter behandlingen. For spørsmålet om effekten av psykologisk terapi sammenlignet med antidepressive medikamenter på depresjon var gjennomsnittlig depresjonssymptomer 0,5 høyere i gruppen som fikk psykologisk terapi (fra 2,74 lavere til 3,74 høyere målt på Reynolds Adolescent Depression Scale som går fra 30 til 120) målt 12 måneder etter behandling og 0,16 standardavvik høyere målt rett etter behandling (fra 0,35 lavere til 0,68 høy‐ ere). For frafall fra behandling var odds ratio 0,83 (fra 0,38 til 1,79) målt ved behandlingsslutt og 1,17 (0,63‐2,19) 6‐9 måneder etter behandling. Selvmordstanker var målt med suicidal ideation questionnaire Junior High School version. Gjennomsnittlig selvmordstanker (suicidal ideation) var 2,5 lavere (fra 5,09 lavere til 0,09 høyere) etter 12 måneder i gruppen som fikk psykologisk terapi. For spørsmålet om effekten av psykologisk terapi sammenlignet med antidepressive medikamenter i kombinasjon med psykologisk terapi var gjennomsnittlig depresjons‐ symptomer 3,1 lavere målt på Reynolds Adolescent Depression Scale som går fra 30 til 120 (fra 6,38 lavere til 0,18 høyere) for gruppen som fikk kombinasjonen psykologisk terapi og antidepressiva og 0,16 standardavvik lavere målt rett etter behandling (fra 0,97 lavere til 0,64 høyere). For frafall fra behandling var odds ratio 0,96 (95 % konfidensintervall 0,27 til 3,41) målt ved behandlingsslutt og 0,75 (0,40‐1,42) 6‐9 måneder etter behandling. Når det gjaldt suicidale tanker var gjennomsnittlig selvmordstanker 0,9 høyere (fra 1,37 lavere til 3,17 høyere) etter 12 måneder i gruppen som fikk psyko‐ logisk terapi kombinert med antidepressiva. Alle studiene hadde høy risiko for systematiske feil, hovedsakelig på grunn av mang‐ lende blinding av deltagere, helsepersonell og utfallsmåler. Alle studiene hadde for få deltagere med for å så sikre resultater. Vi har også svært liten tillit til resultatene blant annet fordi alle effektestimatene er usikre med brede konfidensintervaller. 

**Diskusjon** 
Vi fant tre studier som hadde vurdert effekten av psykologisk terapi sammenlignet med antidepressiva alene eller kombinert med psykologisk terapi. Studiene har sammenlignet aktive behandlingsformer. Vi fant ingen forskjell mellom de ulike former for terapier og det er vanskelig å si hva som er mest virksomt av de ulike terapier eller kombinasjoner av disse. En begrensning er at vi fant få studier med få deltagere og selv når vi har slått studiene sammen i metaanalyser har vi stor usikkerhet rundt effektestimatet. Forskningen må ha lang nok oppfølgingstid for å kunne avdekke om deltagerne blir bedre på lang sikt. Det var kun to av de tre studiene som hadde målt forskjell i effekter over tid. Det vil være vanskelig å avdekke forbedring når studien kun måler effekten rett etter et 16 ukers behandlingsopplegg. For å oppdatere to spørsmål fra Cochrane‐oversikten søkte vi etter nyere randomiserte studier. Den studien vi fant var publisert i 2015, men inkluderte barn i 2007. Det er for tiden pågående studier, så det er mulig at vi i framtiden kan trekke sikrere konklusjoner. 

**Konklusjon** 
Med utgangspunkt i tre randomiserte kontrollerte studier hvor totalt 481 barn mellom 11 og 18 år deltok, kan vi ikke si noe sikkert om effekten av psykologisk terapi sammenlignet med antidepressive medikamenter alene eller antidepressive medikamenter i kombinasjon med psykologisk terapi for barn og unge med depresjon eller depresjonssymptomer.
AU  - Dalsbø,
AU  - K.
AU  - T.
AU  - Siqveland,
AU  - J.
AU  - Dahm,
AU  - K.
AU  - T.
AU  - Reinar,
AU  - L.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/effekter-av-psykologisk-behandling-vs-antidepressiva-barn-og-unge-rapport-2017.pdf
PY  - 2017
T2  - Folkehelseinstituttet
TI  - Effekter av psykologisk terapi sammenlignet med antidepressive medikamenter alene eller i kombinasjon med psykologisk terapi for barn og unge med depresjon eller depresjonssymptomer: en systematisk oversikt
ER  -
TY  - JOUR
AB  - Martial arts are becoming a mainstream sport for energetic youth and their popularity extends globally. Following a comprehensive search of martial arts research, a critical review of the field and the psychological implications was conducted. 

The resulting meta-analysis examined the effect of martial arts on problematic externalizing behavior (aggression, anger, and violence). The final meta-analysis included twelve studies, with 507 participants (ages 6 to 18), where study type was a moderator. For nine intervention and longitudinal studies, there was a homogenous effect size of 0.65 (95% CI: 0.11, 1.03) indicating a medium effect, where martial arts improved aggression amongst the practicing youth. 

The other three one-time comparisons studies did not yield a homogenous effect size. Based on these analyses, it appears that martial arts has a potential to reduce externalizing behaviors in youth, although further research is needed to determine the mechanisms of change and specify the most relevant population groups for targeted interventions. 

Copyright &copy; 2017 Elsevier Ltd.
AN  - 614676084
AU  - Harwood,
AU  - A.
AU  - Lavidor,
AU  - M.
AU  - Rassovsky,
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.avb.2017.03.001
L1  - internal-pdf://2721898269/Harwood-2017-Reducing aggression with martial.pdf
PY  - 2017
TI  - Reducing aggression with martial arts: A meta-analysis of child and youth studies
UR  - http://www.elsevier.com/locate/aggviobeh
VL  - 09
ER  -
TY  - JOUR
AB  - This systematic review of reviews synthesizes evidence on the impact of interventions to prevent violence against adolescent girls and young women 10-24 years (VAWG) in low- and middle-income countries (LMICs). 

Theories of women&#039;s empowerment and the social ecology of multifaceted violence frame the review. Child abuse, female genital mutilation/cutting (FGMC), child marriage, intimate partner violence (IPV), and sexual violence were focal outcomes. 

Our review followed the Assessment of Multiple Systematic Reviews (AMSTAR) for the systematic review of reviews, and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) for a systematic review of recent intervention studies. 

Of 35 reviews identified between June 7 and July 20, 2016, 18 were non-duplicate systematic reviews of medium-to-high quality. 
Half of these 18 reviews focused on interventions to prevent IPV. Only four focused on adolescents, of which three focused on child marriage and one compared findings across early and late adolescence. 

None focused on interventions to prevent child abuse or sexual violence in adolescent/young women. From these 18 reviews and the supplemental systematic review of intervention studies, data were extracted on 34 experimental or quasi-experimental intervention studies describing 28 interventions. 

Almost all intervention studies measured impacts on one form of VAWG. Most studies assessed impacts on child marriage (n = 13), then IPV (n = 8), sexual violence (n = 4), child abuse (n = 3), and FGMC (n = 3). Interventions included 1-6 components, involving skills to enhance voice/agency (n = 17), social networks (n = 14), human resources like schooling (n = 10), economic incentives (n = 9), community engagement (n = 11) and community infrastructure development (n = 6). 

Bundled individual-level interventions and multilevel interventions had more favorable impacts on VAWG. Interventions involving community engagement, skill-building to enhance voice/agency, and social-network expansion show promise to reduce VAWG. 

Future interventions should target poly-victimization, compare impacts across adolescence, and include urban, out-of-school, married, and displaced/conflict-affected populations in LMICs, where VAWG may be heightened.
AN  - 28941786
AU  - Yount,
AU  - K.
AU  - M.
AU  - Krause,
AU  - K.
AU  - H.
AU  - Miedema,
AU  - S.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.socscimed.2017.08.038
L1  - internal-pdf://4281414173/Yount-2017-Preventing gender-based violence vi.pdf
PY  - 2017
SP  - 1-13
TI  - Preventing gender-based violence victimization in adolescent girls in lower-income countries: Systematic review of reviews
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28941786
VL  - 192
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
The aim of this study was to perform a systematic review to identify, evaluate and summarise studies on the administration of therapeutic massage to preterm neonates during their stay in the NICU, and to assess their methodological quality. 

**DESIGN:**
systematic review following PRISMA statements guidelines. 

**DATA SOURCES: **
A comprehensive search was performed including relevant articles between January 2004 and December 2013, using the following electronic databases: Medline, PEDro, Web of Science and Scopus. 

**REVIEW METHODS: **
Two reviewers conducted a review of the selected articles: one evaluated the methodological quality of the studies and performed data extraction and the other performed a cross-check. Divergences of opinion were resolved by discussion with a third reviewer. The studies reviewed implemented a wide variety of interventions and evaluation methods, and therefore it was not possible to perform a meta-analysis. The following data were extracted from each article: year of publication, study design, participants and main measurements of outcomes obtained through the intervention. A non-quantitative synthesis of the extracted data was performed. Level of evidence was graded using the Jadad Scale. 

**RESULTS: **
A total of 23 articles met the inclusion criteria and were thus included in the review; these presented a methodological quality ranging from 1 to 5 points (with a mean of 3 points). Most studies reported that the administration of various forms of therapeutic massage exerted a beneficial effect on factors related to the growth of preterm infants. The causes indicated by the researchers for these anthropometric benefits included increased vagal activity, increased gastric activity and increased serum insulin levels. Other demonstrated benefits of massage therapy when administered to hospitalised preterm infants included better neurodevelopment, a positive effect on brain development, a reduced risk of neonatal sepsis, a reduction in length of hospital stay and reduced neonatal stress. 

**CONCLUSIONS: **
Although based on a qualitative analysis of heterogeneous data, the present review suggests that a clear benefit is obtained from the administration of massage therapy in hospitalised preterm infants, a finding which should encourage the more generalised use of massotherapy in NICU clinical practice.

Copyright &copy; 2017 Elsevier Ltd. All rights reserved.
AN  - 28235686
AU  - Alvarez,
AU  - M.
AU  - J.
AU  - Fernandez,
AU  - D.
AU  - Gomez-Salgado,
AU  - J.
AU  - Rodriguez-Gonzalez,
AU  - D.
AU  - Roson,
AU  - M.
AU  - Lapena,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ijnurstu.2017.02.009
L1  - internal-pdf://1919121222/Alvarez-2017-The effects of massage therapy in.pdf
PY  - 2017
SP  - 119-136
TI  - The effects of massage therapy in hospitalized preterm neonates: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28235686
VL  - 69
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) is one of the most common and a debilitating neuro-behavior disorder in the pediatric population. Although numerous effective psychostimulants are available, more than 30% of patients still do not show adequate treatment response rendering diverse pharmacological options. 

We aimed at assessing the efficacy and safety of modafinil in the treatment of children and adolescents with ADHD by conducting a meta-analysis. An extensive search of databases and clinical trial registries resulted in five published short-term randomized, double-blind, placebo-controlled trials. 

Primary efficacy measures were mean change in ADHD Rating Scale-IV Home (ADHD-RS-IV Home) and School Version (ADHD-RS-IV School) from baseline to study end point. The results showed that modafinil more significantly improved ADHD-RS-IV Home (SMD, -0.77 [95%CI, -1.11 to -0.44]) and School (SMD, -0.71 [95%CI, -0.96 to -0.47]) than placebo. 

Dropout rate due to adverse event did not significantly differ between two groups. In terms of commonly observed side effects, modafinil showed significantly higher incidence of decreased appetite (RR = 5.02, 95% CIs, 2.55 to 9.89, P &lt; 0.00001) and insomnia (RR = 6.16, 95% CIs, 3.40 to 11.17, P &lt; 0.00001). 

Modafinil did not cause a clinically significant increase of heart rate, systolic blood pressure, and diastolic blood pressure. Although we found that modafinil may be another treatment option in children and adolescents with ADHD, the results should be interpreted and translated into clinical practice with caution, as the meta-analysis was based on a limited number of clinical trials. 

Copyright A&copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Wang, Sheng-Min. Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, Republic of Korea. Han, Changsu. Department of Psychiatry, Korea University, College of Medicine, Seoul, Republic of Korea. Lee, Soo-Jung. Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, Republic of Korea. Jun, Tae-Youn. Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, Republic of Korea. Patkar, Ashwin A. Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA. Masand, Prakash S. Global Medical Education, New York, NY, USA. Pae, Chi-Un. Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, Republic of Korea; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA. Electronic address: pae@catholic.ac.kr.
AN  - 27810669
AU  - Wang,
AU  - S.
AU  - M.
AU  - Han,
AU  - C.
AU  - Lee,
AU  - S.
AU  - J.
AU  - Jun,
AU  - T.
AU  - Y.
AU  - Patkar,
AU  - A.
AU  - A.
AU  - Masand,
AU  - P.
AU  - S.
AU  - Pae,
AU  - C.
AU  - U.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jpsychires.2016.09.034
DP  - Ovid Technologies
J2  - J Psychiatr Res
L1  - internal-pdf://1158472907/Wang-2017-Modafinil for the treatment of atten.pdf
LA  - English
N1  - Wang, Sheng-Min Han, Changsu Lee, Soo-Jung Jun, Tae-Youn Patkar, Ashwin A Masand, Prakash S Pae, Chi-Un S0022-3956(16)30177-7
PY  - 2017
SP  - 292-300
T2  - Journal of Psychiatric Research
TI  - Modafinil for the treatment of attention-deficit/hyperactivity disorder: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27810669http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27810669&amp;id=doi:10.1016%2Fj.jpsychires.2016.09.034&amp;issn=0022-3956&amp;isbn=&amp;volume=84&amp;issue=1&amp;spage=292&amp;pages=292-300&amp;date=2017&amp;title=Journal+of+Psychiatric+Research&amp;atitle=Modafinil+for+the+treatment+of+attention-deficit%2Fhyperactivity+disorder%3A+A+meta-analysis.&amp;aulast=Wang&amp;pid=%3Cauthor%3EWang+SM%3C%2Fauthor%3E%3CAN%3E27810669%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0022395616301777/1-s2.0-S0022395616301777-main.pdf?_tid=bbcb8ca0-04d1-11e7-9c1a-00000aab0f6b&amp;acdnat=1489068630_b8114d9c77fe4cbffe6d9414bd0b39d0
VL  - 84
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Despite progress in the development of evidence-based interventions for youth psychiatric problems, up to 75% of youths with mental health needs never receive services, and early dropout is common among those who do. If effective, then single-session interventions (SSIs) for youth psychiatric problems could increase the accessibility, scalability, completion rates, and cost-effectiveness of youth mental health services. This study assessed the effects of SSIs for youth psychiatric problems. 

**METHOD: **
Using robust variance estimation to address effect size (ES) dependency, findings from 50 randomized-controlled trials (10,508 youths) were synthesized. 

**RESULTS: **
Mean postintervention ES showed a Hedges g value equal to 0.32; the probability that a youth receiving SSI would fare better than a control-group youth was 58%. Effects varied by several moderators, including target problem: ESs were largest for anxiety (0.56) and conduct problems (0.54) and weakest for substance abuse (0.08; targeted in &gt;33% of studies). Other problems yielded numerically promising but nonsignificant ESs (e.g., 0.21 for depression), potentially from low representation across trials. ESs differed across control conditions, with larger ESs for studies with no treatment (0.41) versus active controls (0.14); developmental periods, with greater ESs for children (0.42) than adolescents (0.19); intervention types, with largest ESs for youth-focused cognitive-behavioral approaches (0.74); and follow-up lengths, with smaller ESs for follow-ups exceeding 13 weeks. ESs did not differ for self- versus therapist-administered interventions or for youths with diagnosable versus subclinical problems. 

**CONCLUSION: **
Findings support the promise of SSIs for certain youth psychiatric problems and the need to clarify how, to what degree, and for whom SSIs effect lasting change. 

Copyright &copy; 2016 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
AD  - Schleider, Jessica L. Harvard University, Cambridge, MA. Electronic address: jschleider@fas.harvard.edu. Weisz, John R. Harvard University, Cambridge, MA.
AN  - 28117056
AU  - Schleider,
AU  - J.
AU  - L.
AU  - Weisz,
AU  - J.
AU  - R.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jaac.2016
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
L1  - internal-pdf://2627123136/Schleider-2017-Little Treatments, Promising Ef.pdf
LA  - English
M3  - Review
N1  - Schleider, Jessica L Weisz, John R S0890-8567(16)31933-5
PY  - 2017
SP  - 107-115
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Little Treatments, Promising Effects? Meta-Analysis of Single-Session Interventions for Youth Psychiatric Problems
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28117056http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28117056&amp;id=doi:10.1016%2Fj.jaac.2016.11.007&amp;issn=0890-8567&amp;isbn=&amp;volume=56&amp;issue=2&amp;spage=107&amp;pages=107-115&amp;date=2017&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Little+Treatments%2C+Promising+Effects%3F+Meta-Analysis+of+Single-Session+Interventions+for+Youth+Psychiatric+Problems.&amp;aulast=Schleider&amp;pid=%3Cauthor%3ESchleider+JL%3C%2Fauthor%3E%3CAN%3E28117056%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0890856716319335/1-s2.0-S0890856716319335-main.pdf?_tid=72cf1c58-04cf-11e7-8d24-00000aab0f26&amp;acdnat=1489067648_fb554325cc4a1377af0f0e8ce336a615
VL  - 56
ER  -
TY  - JOUR
AB  - Background: 
Antisocial behaviour and conduct disorders are the most common behavioural and mental health problems in children and young people globally. An efficacious intervention is needed to manage these antisocial behaviours that have costly consequences. Multisystemic Therapy (MST), an intensive home-based intervention for youths with psychosocial and behavioural problems, is recommended under National Institute for Health and Clinical Excellence guidelines for conduct disorder. However, reviews on the efficacy of MST are mixed. 

Aim: 
To review randomised controlled trials (RCTs) reporting efficacy of MST among youths presenting with antisocial behaviour and emotional disorder respectively. 

Method: 
A systematic map term to subject heading search was conducted in PsycINFO, Embase, and Ovid Medline databases for articles up to November 2015. RCTs comparing MST vs.treatment as usual (TAU) in youths presenting with antisocial behaviour and emotional disorder were included. 

Results: 
12 RCTs (n = 1425) reported efficacy of MST vs. TAU in youths presenting with antisocial behaviour and emotional disorder. Clinically significant treatment effects of MST showed a reduction of antisocial behaviour which includes delinquency. MST, vs. psychiatric hospitalisation, was associated with a reduction of suicidal attempts in youths presenting with psychiatric emergencies. 4 studies showed that MST was less costly than TAU in the short term, with further analysis required for long-term cost-effectiveness. 

Conclusion: 
MST is an efficacious intervention for severe antisocial behaviours in reduction of delinquency and should be included in clinical practices. MST was shown to have a positive effect on emotional disorder but further research is needed to evaluate the efficacy of MST with emotional disorder. Further analysis is required to assess the services utilized for long-term cost effectiveness.
AN  - 29181092
AU  - Tan,
AU  - J.
AU  - X.
AU  - Fajardo,
AU  - M.
AU  - L.
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/17571472.2017.1362713
L1  - internal-pdf://1475363504/Tan-2017-Efficacy of multisystemic therapy in.pdf
PY  - 2017
SP  - 95-103
T2  - London Journal of Primary Care
TI  - Efficacy of multisystemic therapy in youths aged 10-17 with severe antisocial behaviour and emotional disorders: systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=29181092
VL  - 9
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
During the past decades deinstitutionalisation policies have led to a transition from inpatient towards community mental health care. Many European countries implement Assertive Community Treatment (ACT) as an alternative for inpatient care for &quot;difficult to reach&quot; children and adolescents with severe mental illness. ACT is a well-organized low-threshold treatment modality; patients are actively approached in their own environment, and efforts are undertaken to strengthen the patient&#039;s motivation for treatment. The assumption is that ACT may help to avoid psychiatric hospital admissions, enhance cost-effectiveness, stimulate social participation and support, and reduce stigma. ACT has been extensively investigated in adults with severe mental illness and various reviews support its effectiveness in this patient group. However, to date there is no review available regarding the effectiveness of youth-ACT. It is unknown whether youth-ACT is as effective as it is in adults. This review aims to assess the effects of youth-ACT on severity of psychiatric symptoms, general functioning, and psychiatric hospital admissions. 

**METHOD: **
A systematic literature search was conducted in PubMed, Cochrane Library, PsychINFO and CINAHL published up to March 2017. To assess methodological quality of the included studies, the Oxford Centre of Evidence-Based Medicine grading system was used. 

**RESULTS:**
Thirteen studies were included in this review. There are indications that youth-ACT is effective in reducing severity of psychiatric symptoms, improving general functioning, and reducing duration and frequency of psychiatric hospital admissions. 

**CONCLUSIONS: **
The current literature on youth-ACT is limited but promising. There are indications that youth-ACT is effective in reducing severity of psychiatric symptoms, improving general functioning, and reducing duration and frequency of psychiatric hospital admissions. The effect of youth-ACT may be comparable with the effect of ACT in adults. Similar as in adult ACT, the studies on youth-ACT found effects that vary from small to large. Randomized experimental research designs are needed to further corroborate effectiveness.
AN  - 28768492
AU  - Vijverberg,
AU  - R.
AU  - Ferdinand,
AU  - R.
AU  - Beekman,
AU  - A.
AU  - van
AU  - Meijel,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s12888-017-1446-4
L1  - internal-pdf://0064744255/Vijverberg-2017-The effect of youth assertive.pdf
PY  - 2017
SP  - 284
T2  - BMC Psychiatry
TI  - The effect of youth assertive community treatment: a systematic PRISMA review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=28768492
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541424/pdf/12888_2017_Article_1446.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
This review aims to summarise evidence on the effectiveness of interventions to prevent youth violence in Latin America. 

**METHODS: **
A systematic search on 13 academic databases was conducted to locate studies evaluating a primary or secondary prevention intervention in Latin America. Studies could use any type of quantitative design to assess outcomes related to youth violence. A search of websites, references and citation searching was also carried out. The quality of each study was assessed. 

**RESULTS: **
Nine studies were identified. Most documented positive effects of the interventions on the perception of youth violence present in the community/school. Evidence was found of a reduction in homicides and juvenile crimes in three studies, two of which evaluated a community-based intervention. There were mixed results for the self-report of participation on violent acts. The majority of the studies lacked of a rigorous design. 

**CONCLUSIONS: **
Most of the interventions had some promising results, including the reduction of homicides within communities. Community-based programmes were the most consistent regarding an effectiveness to prevent violence. However, the evidence for Latin America is still scarce and relies on non-rigorously designed studies.
AN  - 27766375
AU  - Atienzo,
AU  - E.
AU  - E.
AU  - Baxter,
AU  - S.
AU  - K.
AU  - Kaltenthaler,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00038-016-0909-6
L1  - internal-pdf://0745530365/Atienzo-2017-Interventions to prevent youth vi.pdf
PY  - 2017
SP  - 15-29
TI  - Interventions to prevent youth violence in Latin America: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med8&amp;AN=27766375
VL  - 62
ER  -
TY  - JOUR
AB  - **Background: **
Aggression and irritability in children occur across a range of diagnoses, and are associated with both economic cost and negative psychosocial outcomes. Antipsychotics are frequently prescribed in these cases.

**Methods: **
A random effects meta-analysis of 14 random controlled trials was conducted. Overall effect sizes for antipsychotics for irritability and aggression were extracted. Subgroup analyses were conducted according to diagnostic indication, specific medication and degree of sedation. Meta-regression examined effects of antipsychotic dose. 

**Results:**
Overall, antipsychotics were effective in reducing aggression and irritability (SMD = 0.74, 95% confidence interval [CI] 0.57-0.92, z = 8.4, p &lt; 0.0001). In stratified subgroup analysis, individual antipsychotic agents did not differ in efficacy (chi2 = 1.1, df = 3, p = 0.78). However, aripiprazole and risperidone demonstrated significant benefit over placebo. Antipsychotic efficacy did not differ significantly based on diagnostic indication (chi2 = 4.2, df = 4, p = 0.39). Meta-regression showed no overall dose effect.

**Conclusions: **
Clinical data supports the efficacy of risperidone and aripiprazole for aggression and irritability across diagnoses, with insufficient data available for other agents. Available data does not support a difference in efficacy based on underlying diagnosis, choice of agent, or its degree of sedation. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-41282-010
AU  - van
AU  - Schalkwyk,
AU  - G.
AU  - I.
AU  - Lewis,
AU  - A.
AU  - S.
AU  - Beyer,
AU  - C.
AU  - Johnson,
AU  - J.
AU  - van
AU  - Rensburg,
AU  - S.
AU  - Bloch,
AU  - M.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/14737175.2017.1371012
L1  - internal-pdf://1535888675/van Schalkwyk-2017-Efficacy of antipsychotics.pdf
PY  - 2017
SP  - 1045-1053
TI  - Efficacy of antipsychotics for irritability and aggression in children: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-41282-010
VL  - 17
ER  -
TY  - JOUR
AB  - Child physical abuse is an issue of global concern. Conservative estimates set global prevalence of this type of maltreatment at 25%, its consequences and cost to society escalating with increasing frequency and severity of episodes. 

Syntheses of the evidence on parenting programs for reducing rates of physical abuse recidivism have, to date, not been able to establish effectiveness. Paucity of data and inconsistent inclusion criteria in past reviews made meta-analysis often impossible or uninformative. 

The current systematic review updates prior reviews and overcomes some of the methodological issues they encountered by pooling trial-level data from a well-defined scope of trials of parenting interventions aimed at preventing the re-abuse of children by parents with substantiated or suspected physical abuse history. 

Randomized controlled trials and rigorous non-randomized designs were sought via nine online databases, two trial registries, several clearinghouses and contact with experts. A total of fourteen studies of variable quality were included in this review, four of which had outcomes that enabled meta-analysis. 

Overall, this review presents evidence supporting the effectiveness of parenting behavioral programs based on social learning theory for reducing hard markers of child physical abuse recidivism. Meta-analysis found that the absolute risk reduction in risk of recidivism was 11 percentage points less for maltreating parents who undergo parenting programs (RD = -0.11, 95% CI [-0.22, -0.004], p = 0.043, I &lt;sup&gt;2&lt;/sup&gt; = 28.9%). 

However, the pooled effect size was not statistically significant when calculated as a risk ratio (0.76, 95% CI [0.54, 1.07], I &lt;sup&gt;2&lt;/sup&gt; = 38.4%). 

Policy makers and practitioners should be made aware that this intervention method is backed by promising evidence featuring modest yet significant reductions in hard markers of child physical abuse, even though the methodological robustness of these findings should be further explored in future research.
AN  - 28378136
AU  - Vlahovicova,
AU  - K.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Leijten,
AU  - P.
AU  - Knerr,
AU  - W.
AU  - Gardner,
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-017-0232-7
L1  - internal-pdf://0269263358/Vlahovicova-2017-Parenting Programs for the Pr.pdf
PY  - 2017
SP  - 351-365
TI  - Parenting Programs for the Prevention of Child Physical Abuse Recurrence: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28378136
VL  - 20
ER  -
TY  - JOUR
AB  - **Background: **
Omega-3 (or n-3) polyunsaturated fatty acids (PUFAs) are promising antidepressant treatments for perinatal depression (PND) because of supporting evidence from clinical trials, the advantage in safety, and their anti-inflammatory and neuroplastic effects. Although several observational studies have shown n-3 PUFA deficits in women with PND, the results of individual PUFAs from different studies were inconsistent. 

**Methods: **
This systematic review and meta-analysis aims to compare the levels of PUFA indices, including eicosapentaenoic acid, docosahexaenoic acid, arachidonic acid, total n-3, total n-6, and the n-6/n-3 ratio between women with PND and healthy control subjects. The meta-analysis included 12 eligible studies available as of December 2016. The effect sizes were synthesized by using a random effects model. In addition, we performed subgroup analysis for the PUFA levels in patients with prenatal and postnatal depression, both of which were compared with healthy control subjects.

**Results: **
There were significantly lower levels of total n-3 PUFAs and docosahexaenoic acid and significantly increased n-6/n-3 ratios in PND patients. In the subgroup analyses, there were significantly lower levels of n-3 PUFAs, eicosapentaenoic acid, and docosahexaenoic acid in women with prenatal depression. The n-6/n-3 ratio was significantly increased in both prenatal and postnatal depression subgroups. 

**Conclusions: **
Our meta-analysis consolidates the important role of n-3 PUFAs in PND. Nutritional medicine is an important strategy to improve the effectiveness of treatment for depression, and our findings provide the strong rationale to conduct clinical trials to test the therapeutic and prophylactic effects of n-3 PUFAs in PND. 

Copyright &copy; 2017 Society of Biological Psychiatry.
AN  - 615344060
AU  - Lin,
AU  - P.
AU  - Y.
AU  - Chang,
AU  - C.
AU  - H.
AU  - Chong,
AU  - M.
AU  - F.
AU  - F.
AU  - Chen,
AU  - H.
AU  - Su,
AU  - K.
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.biopsych.2017.02.1182
L1  - internal-pdf://0975082287/Lin-2017-Polyunsaturated Fatty Acids in Perina.pdf
PY  - 2017
TI  - Polyunsaturated Fatty Acids in Perinatal Depression: A Systematic Review and Meta-analysis
UR  - http://www.elsevier.com/locate/biopsychiat
VL  - 26
ER  -
TY  - JOUR
AB  - **Objective: **
To systematically review and quantify the effectiveness of Eating Disorder (ED) prevention interventions. 

**Methods: **
Electronic databases (including the Cochrane Controlled Trial Register, MEDLINE, PsychInfo, EMBASE, and Scopus) were searched for published randomized controlled trials of ED prevention interventions from 2009 to 2015. Trials prior to 2009 were retrieved from prior reviews. 

**Results: **
One hundred and twelve articles were included. Fifty-eight percent of trials had high risk of bias. Findings indicated small to moderate effect sizes on reduction of ED risk factors or symptoms which occurred up to three-year post-intervention. For universal prevention, media literacy (ML) interventions significantly reduced shape and weight concerns for both females (-0.69, confidence interval (CI): -1.17 to -0.22) and males (-0.32, 95% CI -0.57 to -0.07). For selective prevention, cognitive dissonance (CD) interventions were superior to control interventions in reducing ED symptoms (-0.32, 95% CI -0.52 to -0.13). Cognitive behavioural therapy (CBT) interventions had the largest effect size (-0.40, 95% CI -0.55 to -0.26) on dieting outcome at 9-month follow-up while the healthy weight intervention reduced ED risk factors and body mass index. No indicated prevention interventions were found to be effective in reducing ED risk factors. 

**Conclusions: **
There are a number of promising preventive interventions for ED risk factors including CD, CBT and ML. Whether these actually lower ED incidence is, however, uncertain. Combined ED and obesity prevention interventions require further research. (C) 2017 Elsevier Ltd. All rights reserved.
AN  - WOS:000400459500004
AU  - Le,
AU  - L.
AU  - K.
AU  - D.
AU  - Barendregt,
AU  - J.
AU  - J.
AU  - Hay,
AU  - P.
AU  - Mihalopoulos,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2017.02.001
L1  - internal-pdf://1597314066/Le-2017-Prevention of eating disorders_ A syst.pdf
N1  - Kristine Ludvigsen (2017-12-22 21:32:38)(Select): litt uklar på alder to studier er voksne. men resten (overvekten) er på barn og unge så jeg inkluderer den;
PY  - 2017
SP  - 46-58
TI  - Prevention of eating disorders: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000400459500004
VL  - 53
ER  -
TY  - JOUR
AB  - **Objective: **
Youth at clinical high risk (CHR) for psychosis often demonstrate significant negative symptoms, which have been reported to be predictive of conversion to psychosis and a reduced quality of life but treatment options for negative symptoms remain inadequate. Therefore, we conducted a systematic review and network meta-analysis of all intervention studies examining negative symptom outcomes in youth at CHR for psychosis. 

**Method: **
The authors searched PsycINFO, Medline, Embase, CINAHL, and EBM from inception to December 2016. Studies were selected if they included any intervention that reported follow-up negative symptoms in youth at CHR for psychosis. Treatment comparisons were evaluated using both pairwise and network meta-analyses. Due to the differences in negative symptom scales the effect sizes were reported as the standardized mean difference (SMD). 

**Results: **
Of 3027 citations, 32 studies met our inclusion criteria, including a total of 2463 CHR participants. N-methyl-D-aspartate-receptor (NMDAR) modulators trended toward a significant reduction in negative symptoms compared to placebo (SMD = -0.54; 95% CI = -1.09 to 0.02; I2 = 0%, P = .06). 

In respective order of descending effectiveness as per the treatment hierarchy, NMDAR modulators were more effective than family therapy, need-based interventions, risperidone, amisulpride, cognitive behavioral therapy, omega-3, olanzapine, supportive therapy, and integrated psychological interventions. 

**Conclusions: **
Although this review demonstrated small-large effect sizes between interventions and a reduction in negative symptoms many relevant studies had small samples and the majority was not designed to target negative symptoms, thus reducing their clinical importance with respect to negative symptoms.
AN  - 29069511
AU  - Devoe,
AU  - D.
AU  - J.
AU  - Peterson,
AU  - A.
AU  - Addington,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1093/schbul/sbx139
L1  - internal-pdf://3954221832/Devoe-2017-Negative Symptom Interventions in Y.pdf
PY  - 2017
SP  - 24
TI  - Negative Symptom Interventions in Youth at Risk of Psychosis: A Systematic Review and Network Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=29069511
VL  - 24
ER  -
TY  - GEN
AB  - **Background:** 
Adult smoking usually has its roots in adolescence. If individuals do not take up smoking during this period it is unlikely that they ever will. Further, once smoking becomes established, cessation is challenging; the probability of subsequently quitting is inversely proportional to the age of initiation. One novel approach to reducing the prevalence of youth smoking is the use of incentives.

**Objectives:** 
To assess the effect of incentives on preventing children and adolescents (aged 5 to 18 years) from starting to smoke. It was also our intention to assess, where possible, the dose-response of incentives, the costs of incentive programmes, whether incentives are more or less effective in combination with other interventions to prevent smoking initiation, and any unintended consequences arising from the use of incentives.

**Search methods:** 
For the original review (published 2012) we searched the Cochrane Tobacco Addiction Group Specialized Register, with additional searches of MEDLINE, Embase, CINAHL, CSA databases and PsycINFO for terms relating to incentives, in combination with terms for smoking and tobacco use, and children and adolescents. The most recent searches were of the Cochrane Tobacco Addiction Group Specialized Register, and were carried out in December 2016.

**Selection criteria:** 
We considered randomized controlled trials (RCTs) allocating children and adolescents (aged 5 to 18 years) as individuals, groups or communities to intervention or control conditions, where the intervention included an incentive aimed at preventing smoking uptake. We also considered controlled trials (CTs) with baseline measures and post-intervention outcomes.

**Data collection and analysis:** 
Two review authors extracted and independently assessed the data. The primary outcome was the smoking status of children or adolescents at follow-up who reported no smoking at baseline. We required a minimum follow-up of six months from baseline and assessed each included study for risks of bias. We used the most rigorous definition of abstinence in each trial; we did not require biochemical validation of self-reported tobacco use for study inclusion. Where possible we combined eligible studies to calculate pooled estimates at the longest follow-up, using the Mantel-Haenszel fixed-effect method, grouping studies by study design.

**Main results:** 
We identified three eligible RCTs and five CTs, including participants aged 11 to 14 years, who were non-smokers at baseline. Of the eight trials identified, six had analyzable data relevant for this review, which contributed to meta-analyses (7275 participants in total: 4003 intervention; 3272 control; 2484 participants after adjusting for clustering). All except one of the studies tested the &#039;Smokefree Class Competition&#039; (SFC), which has been widely implemented throughout Europe. In this competition, classes with youth generally between the ages of 11 and 14 years commit to being smoke-free for a six-month period, and report their smoking status regularly. If 90% or more of the class are non-smokers at the end of the six months, the class goes into a competition to win prizes. The one study that was not a trial of the SFC was a controlled trial in which schools in two communities were assigned to the intervention, with schools in a third community acting as controls. Students in the intervention community with lower smoking rates at the end of the project (one school year) received rewards.Most studies resulted in statistically non-significant results. Only one study of the SFC reported a significant effect of the competition on the prevention of smoking at the longest follow-up. However, this study was at risk of multiple biases, and when we calculated the adjusted risk ratio (RR) we no longer detected a statistically significant difference. The pooled RR for the more robust RCTs (3 studies, n = 3056 participants/1107 adjusted for clustering) suggests that there is no statistically significant effect of incentives, in the form of the SFC, to prevent smoking initiation among children and adolescents in the long term (RR 1.00, 95% confidence interval (CI) 0.84 to 1.19). Pooled results from the non-randomized trials also did not detect a significant effect of the SFC, and we were unable to extract data on our outcome of interest from the one trial that did not study the SFC. There is little robust evidence to suggest that unintended consequences (such as making false claims about their smoking status and bullying of smoking students) are consistently associated with such interventions, although this has not been the focus of much research. There was insufficient information to assess the dose-response relationship or to report costs of incentives for preventing smoking uptake.We judged the included RCTs to be at unclear risk of bias, and the non-RCTs to be at high risk of bias. Using GRADE, we rated the overall quality of the evidence for our primary outcome as &#039;low&#039; (for RCTs) and &#039;very low&#039; (for non-RCTs), because of imprecision (all studies had wide confidence intervals), and for the risks of bias identified. We further downgraded the non-RCT evidence, due to issues with the non-RCT study design, likely to introduce further bias.

**Authors&#039; conclusions:** 
The very limited evidence currently available suggests that incentive programmes do not prevent smoking initiation among youth. However, there are relatively few published studies and these are of variable quality. In addition, trials included in the meta-analyses were all studies of the SFC, which distributed small to moderately-sized prizes to whole classes, usually through a lottery system. It is therefore possible that other incentive programmes could be more successful at preventing smoking uptake in young people.Future studies might investigate the efficacy of a wider range of incentives, including those given to individual participants to prevent smoking uptake, whilst considering both the effect of incentives on smoking initiation and the progression to smoking. It would be useful if incentives were evaluated in varying populations from different socioeconomic and ethnic backgrounds, and if intervention components were described in detail.
AN  - CD008645
AU  - Hefler,
AU  - M.
AU  - Liberato,
AU  - S.
AU  - C.
AU  - Thomas,
AU  - D.
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD008645.pub3
KW  - Motivation
KW  - Randomized Controlled Trials as Topic
KW  - Smoking [prevention &amp; control] [psychology]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
L1  - internal-pdf://3498426966/Hefler-2017-Incentives for preventing smoking.pdf
PY  - 2017
T2  - Cochrane Database of Systematic Reviews
TI  - Incentives for preventing smoking in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008645.pub3/abstract
UR  - http://onlinelibrary.wiley.com/store/10.1002/14651858.CD008645.pub3/asset/CD008645.pdf?v=1&amp;t=j82wolxl&amp;s=888fffa5847a7abc7443a3db4aa84acebcbb6f26
ER  -
TY  - JOUR
AB  - Social communication skills are considered a core deficit in children diagnosed with autism spectrum disorder (ASD). Evidence-based practices that have emerged to address these critical skills in children with ASD have largely been implemented by researchers, teachers, and parents. 

Only recently have researchers studied paraprofessionals as implementers of these interventions. The following review examines studies in which paraprofessionals were taught to implement social communication interventions with young children with ASD. 

The seven articles that met inclusion criteria were evaluated with respect to (a) type of social communication intervention, (b) evidence of effectiveness, (c) training methods and components, (d) child outcomes. The primary intervention studies included pivotal response training (PRT), natural language paradigm (NLP), and incidental teaching strategies as well as mand training and general antecedent/consequent interventions. 

All studies reported improvements in paraprofessional implementation fidelity for the chosen intervention, five of which also reported corresponding improvements in child outcomes. Four studies provided definitive evidence of effectiveness for paraprofessional training. Feedback was the only training component used in all seven studies, in conjunction with at least one other component. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-18311-001
AU  - Mrachko,
AU  - A.
AU  - A.
AU  - Kaczmarek,
AU  - L.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0271121416662870
L1  - internal-pdf://2108143630/Mrachko-2017-Examining paraprofessional interv.pdf
PY  - 2017
SP  - 4-15
TI  - Examining paraprofessional interventions to increase social communication for young children with ASD
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-18311-001
VL  - 37
ER  -
TY  - JOUR
AB  - To date, the long-term effectiveness of psychological treatments in reducing post-traumatic stress disorder symptoms in children and adolescents has not been investigated extensively. 

This meta-analysis quantifies the long-term effects of psychological interventions in children and adolescents with PTSD symptoms and examines the period-dependent follow-up (FU) effects based on 47 studies. 

The mean FU effect sizes (ESs) for PTSD symptoms ranged from medium (between treatment ESs for controlled studies) to large (within treatment ESs for uncontrolled studies; pooled analysis including all studies). 

These effects were comparable to the post-treatment ESs, which suggests that the treatment effects remained stable. 

ESs did not differ depending on the length of the FU period (&lt;/&gt;6 months). In randomized controlled trials (RCTs), as well as trials conducted with treatment as usual or active control groups, the long-term treatment effects for the reduction of PTSD symptoms were small. 

These results demonstrate the long-term effectiveness of psychological interventions in the treatment of PTSD in youth. However, more studies should include a FU assessment. 

Further research should focus on RCTs with long-term assessments, report comorbid symptoms and investigate the influence of potential moderators. Research is also warranted to determine how to improve the long-term effects of treatments for PTSD in youth.
AN  - 28815331
AU  - Gutermann,
AU  - J.
AU  - Schwartzkopff,
AU  - L.
AU  - Steil,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10567-017-0242-5
L1  - internal-pdf://1700181406/Gutermann-2017-Meta-analysis of the Long-Term.pdf
PY  - 2017
SP  - 16
TI  - Meta-analysis of the Long-Term Treatment Effects of Psychological Interventions in Youth with PTSD Symptoms
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28815331
VL  - 16
ER  -
TY  - JOUR
AB  - BAKGRUNN
Denne artikkelen er en kunnskapsoppsummering av effektene av tiltaket SMIL (Styrket mestring i livet). Artikkelen er en revisjon av en tidligere beskrivelse av samme tiltaket i Ungsinn (Vis, 2011). SMIL er et gruppebasert lærings- og mestringstilbud for barn og unge i alderen 8-12 år som har foreldre med psykisk sykdom og/ eller rusproblemer. Formålet med tiltaket er å forebygge utviklingsvansker gjennom å gi støtte, informasjon og opplevelse av mestring til barn som pårørende.

METODE
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS og SweMed samt informasjon gitt fra tiltakseier i Norge.

RESULTATER
Ingen effektstudier ble funnet. Tiltakets bakgrunn, innhold og metoder er godt beskrevet i tiltakets materiell. Tiltaket har god forankring i teorier om psykoedukasjon samt om risiko- og beskyttelsesfaktorer som kan påvirke barns psykososiale utvikling i familier hvor foreldre sliter med psykisk sykdom eller rusproblemer. Tiltakseier tilbyr ikke opplæring i programmet, men kan gi råd og veiledning om oppstart av grupper. Det tilbys i liten grad implementeringsstøtte, og det foreligger ikke system for å sikre at tiltaket gjennomføres i tråd med manualen. Det foreligger ingen studier der tiltakets effekt er undersøkt.

KONKLUSJON
SMIL klassifiseres på evidensnivå 2 &ndash; Teoretisk begrunnede tiltak.
AU  - Vis,
AU  - S.
AU  - A.,
AU  - Havnen,
AU  - K.,
AU  - J.,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2017
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: SMIL &ndash; Styrket mestring i livet (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/kunnskapsoppsummering-og-klassifisering-av-tiltaket-smil-styrket-mestring-i-livet-2-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - **Objectives **
To investigate whether exercise, proposed to enhance neuroplasticity and potentially cognitive function (CF) and academic performance (AP), may be beneficial during adolescence when important developmental changes occur. 

**Design **
Systematic review evaluating the impact of acute or chronic exercise on CF and AP in adolescents (13-18 years). 

**Methods **
Nine databases (AMED, AusportMed, CINAHL, COCHRANE, Embase, Medline, Scopus, SPORTdiscus, Web of Science) were searched from earliest records to 31st October 2016, using keywords related to exercise, CF, AP and adolescents. Eligible studies included controlled trials examining the effect of any exercise intervention on CF, AP or both. Effect size (ES) (Hedges g) were calculated where possible. 

**Results **
Ten papers (11 studies) were reviewed. Cognitive domains included: executive function (n = 4), memory (n = 4), attention/concentration (n = 2), visuo-motor speed (n = 1), logical sequencing (n = 1) and psychometric aptitude (n = 1). All papers, nine of 10 being acute studies, reported at least one parameter showing a significant effect of exercise in improving CF and AP. However, the CF parameters displayed substantial heterogeneity, with only 37% favouring acute and chronic exercise. Where ES could be calculated, 52% of the acute CF parameters favoured rest. Memory was the domain most consistently improved by exercise. Academic performance demonstrated a significant improvement with exercise in one of two acute studies and the only chronic study (p &lt;= 0.001). 

**Conclusions **
The evidence for the effect of exercise on CF and AP in adolescents is equivocal and limited in quantity and quality. Well-designed research is therefore warranted to determine the benefits of exercise in enhancing CF and AP and reducing sedentary behaviour. 

Copyright &copy; 2017 Sports Medicine Australia
AN  - 614319229
AU  - Li,
AU  - J.
AU  - W.
AU  - O&#039;Connor,
AU  - H.
AU  - O&#039;Dwyer,
AU  - N.
AU  - Orr,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jsams.2016.11.025
L1  - internal-pdf://2984503939/Li_2017.pdf
PY  - 2017
SP  - 841-848
T2  - Journal of Science and Medicine in Sport
TI  - The effect of acute and chronic exercise on cognitive function and academic performance in adolescents: A systematic review
UR  - http://www.elsevier.com/wps/find/journaldescription.cws_home/707423/description#description
UR  - https://www.sciencedirect.com/science/article/pii/S1440244017302694?via%3Dihub
VL  - 20
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To determine the comparative efficacy and safety of antipsychotics for youth with early-onset schizophrenia using network meta-analytic methods combining direct and indirect trial data. 

**METHOD: **
The authors systematically searched MEDLINE, the Cochrane Library, and clinicaltrials.gov and selected randomized controlled trials allocating youth with schizophrenia spectrum disorders to a (non-clozapine) antipsychotic versus placebo or another antipsychotic. Major efficacy outcomes were Positive and Negative Syndrome Scale (PANSS) total and positive symptoms. Major safety outcomes were weight, plasma triglyceride levels, extrapyramidal symptoms, akathisia, and all-cause discontinuation. Sixteen additional outcomes were analyzed. A random-effects arm-based network meta-analysis was applied, and consistency was assessed by pairwise meta-analysis. Confidence in PANSS total estimates was assessed by applying the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. 

**RESULTS:**
Twelve 6- to 12-week trials (N = 2,158; 8-19 years old; 61% boys) involving 8 antipsychotics (aripiprazole, asenapine, paliperidone, risperidone, quetiapine, olanzapine, molindone, and ziprasidone) were analyzed. PANSS total symptom change was comparable among antipsychotics (low- to moderate-quality evidence), except ziprasidone (very low- to low-quality evidence), and all antipsychotics were superior to placebo (low- to high-quality evidence), except ziprasidone and asenapine (low- to moderate-quality evidence). PANSS positive changes and additional efficacy outcomes were comparable among antipsychotics. Weight gain was primarily associated with olanzapine; extrapyramidal symptoms and akathisia were associated with molindone; and prolactin increased with risperidone, paliperidone, and olanzapine. Serious adverse events, discontinuation of treatment, sedation, insomnia, or change in triglycerides did not differ among antipsychotics. 

**CONCLUSION: **
This network meta-analysis showed comparable efficacy among antipsychotics for early-onset schizophrenia, except that efficacy appeared inferior for ziprasidone and unclear for asenapine. Adverse reaction profiles varied substantially among the investigated antipsychotics and were largely consistent with prior findings in adults.
AN  - 28219485
AU  - Pagsberg,
AU  - A.
AU  - K.
AU  - Tarp,
AU  - S.
AU  - Glintborg,
AU  - D.
AU  - Stenstrom,
AU  - A.
AU  - D.
AU  - Fink-Jensen,
AU  - A.
AU  - Correll,
AU  - C.
AU  - U.
AU  - Christensen,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2016.12.013
L1  - internal-pdf://1841922654/Pagsberg-2017-Acute Antipsychotic Treatment of.pdf
N1  - Kristine Ludvigsen (2017-12-22 19:43:00)(Select): kvalitetsvurdering i tekst;
PY  - 2017
SP  - 191-202
TI  - Acute Antipsychotic Treatment of Children and Adolescents With Schizophrenia-Spectrum Disorders: A Systematic Review and Network Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=28219485
VL  - 56
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Asthma and anxiety are known to interact, leading to exacerbations for both conditions. This systematic review summarised evidence regarding the effectiveness of cognitive-behavioural therapy (CBT) in reducing anxiety for individuals with asthma, with results presented separately for adults and children. 

**DATA SOURCES: **
PRISMA statement and CRD guidance was followed to conduct and report the current review. Three major electronic databases (Ovid Medline, PsycINFO, and EMBASE) and manual searches were used to find relevant published and unpublished research. 

**STUDY SELECTIONS: **
Sixteen trials (twelve adult and four child) met inclusion criteria, and were evaluated with adapted quality criteria. Both controlled trials and repeated-measure designs were eligible. All CBT intervention formats were eligible (group, individual, computerised, self-help). Nine studies (eight adult and one child) focused upon participants with either an anxiety condition diagnosis or above threshold anxiety scores on a validated measure of anxiety at baseline. 

**RESULTS: **
The review indicates tentative preliminary support for the use of CBT for anxiety in adults with asthma, with the evidence-base for interventions with children appearing promising, but under-developed. Studies were more likely to indicate beneficial effects where anxiety-focused (rather than illness-focused) intervention protocols were utilised, asthma-related education was provided and where the trials focused on individuals with likely clinical levels of anxiety at baseline. 

**CONCLUSION: **
Whilst further high quality research is needed, available evidence is supportive of anxiety-focused CBT interventions tailored to target the particular mechanisms thought to maintain this comorbidity in asthma.
AN  - 28759284
AU  - Pateraki,
AU  - E.
AU  - Morris,
AU  - P.
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/02770903.2017.1350967
L1  - internal-pdf://2928709668/Pateraki-2017-Effectiveness of cognitive behav.pdf
PY  - 2017
SP  - 0
TI  - Effectiveness of cognitive behavioural therapy in reducing anxiety in adults and children with asthma: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28759284
ER  -
TY  - JOUR
AB  - **Objectives: **
Digital-based parent training (DPT) programs for parents of children with disruptive behaviors have been developed and tested in randomized trials. The aim of this study was to quantitatively assess the efficacy of these programs versus a control condition. 

**Methods: **
We conducted a systematic review and random effects meta-analysis of peer-reviewed randomized studies comparing DPT targeting children with disruptive behaviors versus a control group (wait list or no treatment). 

**Results: **
Altogether, seven studies (n = 718) were meta-analyzed. Compared to the control groups, DPT resulted in significantly greater improvement in child behavior (effect size [ES] = 0.44, 95% confidence interval [CI] = 0.21-0.66, studies = 7), parent behavior (ES = 0.41, 95% CI = 0.25-0.57, studies = 6), and parental confidence (ES = 0.36, 95% CI = 0.12-0.59, studies = 4). The improvement in child behavior was moderated by age group and severity of clinical presentation, which overlapped 100%. While DPT was superior to control conditions in studies of young children (mean age &lt;7 years) with a clinical range of disruptive behaviors (ES = 0.61, 95% CI = 0.40-0.82, studies = 4), results were nonsignificant in studies of older children (mean age &gt;11 years) with a nonclinical range of symptoms (ES = 0.21, 95% CI = -0.01 to 0.42, studies = 3). Analyses yielded similar results of higher ESs favoring studies of young children with clinical range disruptive behaviors for parent behavior and parental confidence, but the differences were not significant. Results further suggested that in studies of younger children, interactive programs (e.g., computerized programs) were more effective in improving child behavior compared to noninteractive programs (e.g., watching video clips) (p &lt; 0.05). 

**Conclusion:** 
Although additional studies are needed, DPT holds promise as a potentially scalable evidence-based treatment of children with disruptive behaviors that can save human resources. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Baumel, Amit: abaumel@northwell.edu Baumel, Amit: Northwell Health, Zucker-Hillside Hospital, 75-59 263rd Street, Glen Oaks, NY, US, 11004, abaumel@northwell.edu Baumel, Amit: Northwell Health, Zucker-Hillside Hospital, Glen Oaks, NY, US Pawar, Aditya: Northwell Health, Zucker-Hillside Hospital, Glen Oaks, NY, US Kane, John M.: Northwell Health, Zucker-Hillside Hospital, Glen Oaks, NY, US Correll, Christoph U.: Northwell Health, Zucker-Hillside Hospital, Glen Oaks, NY, US
AN  - 2016-49551-011
AU  - Baumel,
AU  - A.
AU  - Pawar,
AU  - A.
AU  - Kane,
AU  - J.
AU  - M.
AU  - Correll,
AU  - C.
AU  - U.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1089/cap.2016.0048
DP  - Ovid Technologies
KW  - parent, training, technology, conduct, oppositional, treatment
KW  - *Behavior Problems
KW  - *Parent Training
KW  - *Child Characteristics
KW  - Interpersonal &amp; Client Centered &amp; Humanistic Therapy [3314]
KW  - Human Childhood (birth-12 yrs) Adulthood (18 yrs &amp; older)
L1  - internal-pdf://3193998618/Baumel-2016-Digital parent training for childr.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 740-749
T2  - Journal of Child and Adolescent Psychopharmacology
TI  - Digital parent training for children with disruptive behaviors: Systematic review and meta-analysis of randomized trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-49551-011http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1089%2Fcap.2016.0048&amp;issn=1044-5463&amp;isbn=&amp;volume=26&amp;issue=8&amp;spage=740&amp;pages=740-749&amp;date=2016&amp;title=Journal+of+Child+and+Adolescent+Psychopharmacology&amp;atitle=Digital+parent+training+for+children+with+disruptive+behaviors%3A+Systematic+review+and+meta-analysis+of+randomized+trials.&amp;aulast=Baumel&amp;pid=%3Cauthor%3EBaumel%2C+Amit%3C%2Fauthor%3E%3CAN%3E2016-49551-011%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://online.liebertpub.com/doi/pdfplus/10.1089/cap.2016.0048
VL  - 26
ER  -
TY  - JOUR
AB  - This systematic review investigated the use and efficacy of music listening as an intervention for children and adolescents in clinical and non-clinical settings. Database search was carried out via EMBASE, MEDLINE, PsycARTICLES Full Text, PsycINFO, PubMed together with hand-search in related journals using an age restriction of 0-18 years and the following keywords: music (therapy) AND receptive OR passive. Only original studies that were peer-reviewed were included. 

The searched publication period was between 1980 and up until March, 2015. In summary, 36 studies were identified as satisfying inclusion criteria, 28 being randomized controlled trials. One half of included studies (n = 18) focused on music listening in pediatrics, indicating a significant reduction of pain, anxiety, and distress. 

One quarter of studies were set in mental health contexts (n = 9), and the remaining nine studies were varied in focus and contents, also supporting the beneficial effects of music listening for specific symptom reduction and enhancement of specific skills. Included studies varied with respect to diagnosis, sample size, design, choice and delivery of music and duration of interventions. 

Results show that music listening in health care contexts is a feasible, easily applicable, and cost effective intervention for children and adolescents. As expected with such diversity, there was a marked variability in results. Careful consideration in interpreting the results and also in designing future studies is needed. Clinical and research implications are discussed further. 

Copyright &copy; 2016 Elsevier Ltd
AD  - (Kim) Jeonju, South Korea (Stegemann) University of Music and Performing Arts, Vienna, Austria T. Stegemann, University of Music and Performing Arts, Vienna, Austria. E-mail: stegemann@mdw.ac.at
AN  - 612631820
AU  - Kim,
AU  - J.
AU  - Stegemann,
AU  - T.
DA  - 01 Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.aip.2016.08.007
DP  - Ovid Technologies
KW  - Children and adolescents
KW  - Music listening
KW  - Music medicine
KW  - Music therapy
KW  - Systematic review
KW  - article
KW  - autism
KW  - behavior assessment
KW  - behavior disorder/rh [Rehabilitation]
KW  - behavior observation scale
KW  - Depression Adjective Checklist
KW  - drug resistant epilepsy
KW  - electroencephalography
KW  - emotionality
KW  - human
KW  - motor performance
KW  - music
KW  - outcome assessment
KW  - Positive and Negative Affect Schedule
KW  - priority journal
KW  - randomized controlled trial (topic)
KW  - self concept
KW  - Self-rating Anxiety Scale
KW  - social psychology
KW  - speech therapy
KW  - Verbal production Evaluation Scale
KW  - adolescent
KW  - anxiety
KW  - child
KW  - diagnosis
KW  - distress syndrome
KW  - Embase
KW  - Medline
KW  - mental health
KW  - pain
KW  - pediatrics
KW  - PsycINFO
KW  - publication
KW  - sample size
KW  - skill
KW  - symptom
L1  - internal-pdf://1089872798/Kim-2016-Music listening for children and adol.pdf
LA  - English
PY  - 2016
SP  - 72-85
T2  - Arts in Psychotherapy
TI  - Music listening for children and adolescents in health care contexts: A systematic review
UR  - http://www.sciencedirect.com/science/journal/01974556http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=612631820http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.aip.2016.08.007&amp;issn=0197-4556&amp;isbn=&amp;volume=51&amp;issue=&amp;spage=72&amp;pages=72-85&amp;date=2016&amp;title=Arts+in+Psychotherapy&amp;atitle=Music+listening+for+children+and+adolescents+in+health+care+contexts%3A+A+systematic+review&amp;aulast=Kim&amp;pid=%3Cauthor%3EKim+J.%3C%2Fauthor%3E%3CAN%3E612631820%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0197455616300594/1-s2.0-S0197455616300594-main.pdf?_tid=d04c2700-04c9-11e7-8fa3-00000aacb35f&amp;acdnat=1489065228_3a0e4f327bff39c2046c500eed86758a
VL  - 51
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
The aim of the study was to synthesize the evidence of parent training (PT) as an early intervention for preschool children aged 2.5 to 6 years with ADHD or ADHD symptoms. 

**METHOD: **
A systematic review and meta-analysis was conducted.

**RESULTS: **
Sixteen studies including 1,003 children were analyzed. Parent-rated outcomes revealed moderate effect sizes (ESs; Hedges&#039; g) of 0.51 for ADHD symptoms, 0.4 for conduct problems, and 0.63 for negative parenting. Based on independent assessment, results were only significant for negative parenting. Parent-rated outcomes were sustained at follow-ups of 3 to 12 months. Program type, intervention modality, and child diagnostic status did not moderate the effect. 

**CONCLUSION: **
PT was partially supported as an efficacious intervention for preschool children with ADHD or ADHD symptoms with moderate ESs on parent-rated outcomes, but no significant results on independently assessed ADHD symptoms. 

Copyright &copy; The Author(s) 2016.
AD  - Rimestad, Marie Louise. Aarhus University, Denmark marielr@psy.au.dk. Lambek, Rikke. Aarhus University, Denmark. Zacher Christiansen, Helene. Aarhus University, Denmark. Hougaard, Esben. Aarhus University, Denmark.
AN  - 27179355
AU  - Rimestad,
AU  - M.
AU  - L.
AU  - Lambek,
AU  - R.
AU  - Christiansen,
AU  - H.
AU  - Z.
AU  - Hougaard,
AU  - E.
DA  - May 14
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1087054716648775
DP  - Ovid Technologies
J2  - J Atten Disord
L1  - internal-pdf://0551857019/Rimestad-2016-Short- and Long-Term Effects of.pdf
LA  - English
N1  - Rimestad, Marie Louise Lambek, Rikke Zacher Christiansen, Helene Hougaard, Esben Using Smart Source Parsing May 1087054716648775
PY  - 2016
SP  - 14
T2  - Journal of Attention Disorders
TI  - Short- and Long-Term Effects of Parent Training for Preschool Children With or at Risk of ADHD: A Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=27179355http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27179355&amp;id=doi:10.1177%2F1087054716648775&amp;issn=1087-0547&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2016&amp;title=Journal+of+Attention+Disorders&amp;atitle=Short-+and+Long-Term+Effects+of+Parent+Training+for+Preschool+Children+With+or+at+Risk+of+ADHD%3A+A+Systematic+Review+and+Meta-Analysis.&amp;aulast=Rimestad&amp;pid=%3Cauthor%3ERimestad+ML%3C%2Fauthor%3E%3CAN%3E27179355%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 14
ER  -
TY  - JOUR
AB  - We systematically reviewed the evidence for the efficacy and effectiveness of brief parenting interventions, defined as &lt; 8 sessions in duration, in reducing child externalizing behaviors. While there is significant evidence to support the efficacy of parenting interventions of 8-12 sessions in duration, the public health benefit of these interventions is limited by low participation rates, high attrition rates and the lack of implementation by a wide range of practitioners. 

Brief parenting interventions have the potential to extend the reach and impact of parenting interventions and steer children away from a trajectory of life course persistent behavior problems. A search of four electronic databases was undertaken to identify RCTs conducted on brief parenting interventions. The primary outcome was child externalizing behaviors and secondary outcomes included parenting skills, parental self-efficacy, parental mental health and partner relationship functioning. 

The heterogeneity of included studies prevented a meta-analysis but characteristics of the studies were described. Nine papers summarising the results of eight studies with 836 families in five countries met inclusion criteria. All studies found significant improvements in parent-rated child externalizing behaviors, parenting skills and parenting self-efficacy, relative to control or comparison groups, with findings maintained at follow-up. 

Less consistent findings emerged for parental mental health and partner relationship functioning. This review provides initial evidence that brief parenting interventions may be sufficient to reduce child externalizing behavior problems for some families, however further research is needed. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Tully, Lucy A.: lucytully56@gmail.com Tully, Lucy A.: University of Sydney, Sydney, NSW, Australia, lucytully56@gmail.com Tully, Lucy A.: University of Sydney, Sydney, NSW, Australia Hunt, Caroline: University of Sydney, Sydney, NSW, Australia
AN  - 2015-44137-001
AU  - Tully,
AU  - L.
AU  - A.
AU  - Hunt,
AU  - C.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10826-015-0284-6
DP  - Ovid Technologies
KW  - Parenting, Brief parenting interventions, Parenting skills, Child externalizing behavior
KW  - *Behavior Problems
KW  - *Child Care
KW  - *Externalization
KW  - *Family Intervention
KW  - *Parenting Skills
KW  - Group &amp; Family Therapy [3313]
KW  - Human Adulthood (18 yrs &amp; older)
L1  - internal-pdf://3230718274/Tully-2016-Brief parenting interventions for c.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2016
SP  - 705-719
T2  - Journal of Child and Family Studies
TI  - Brief parenting interventions for children at risk of externalizing behavior problems: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-44137-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10826-015-0284-6&amp;issn=1062-1024&amp;isbn=&amp;volume=25&amp;issue=3&amp;spage=705&amp;pages=705-719&amp;date=2016&amp;title=Journal+of+Child+and+Family+Studies&amp;atitle=Brief+parenting+interventions+for+children+at+risk+of+externalizing+behavior+problems%3A+A+systematic+review.&amp;aulast=Tully&amp;pid=%3Cauthor%3ETully%2C+Lucy+A%3C%2Fauthor%3E%3CAN%3E2015-44137-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s10826-015-0284-6
UR  - http://download.springer.com/static/pdf/750/art%253A10.1007%252Fs10826-015-0284-6.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10826-015-0284-6&amp;token2=exp=1489073992~acl=%2Fstatic%2Fpdf%2F750%2Fart%25253A10.1007%25252Fs10826-015-0284-6.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10826-015-0284-6*~hmac=c3b44b975f5be215a9ed6aa20cc66b255f0526172fb04d8b8aee5b1771cbbb11
VL  - 25
ER  -
TY  - JOUR
AB  - Cognitive Behavior Therapy (CBT) is a well-established treatment for childhood anxiety disorders. Meta-analyses have concluded that approximately 60% of children recover following treatment, however these include studies using a broad range of diagnostic indices to assess outcomes including whether children are free of the one anxiety disorder that causes most interference (i.e. the primary anxiety disorder) or whether children are free of all anxiety disorders. We conducted a meta-analysis to establish the efficacy of CBT in terms of absence of all anxiety disorders. 

Where available we compared this rate to outcomes based on absence of primary disorder. Of 56 published randomized controlled trials, 19 provided data on recovery from all anxiety disorders (n=635 CBT, n=450 control participants). There was significant heterogeneity across those studies with available data and full recovery rates varied from 47.6 to 66.4% among children without autistic spectrum conditions (ASC) and 12.2 to 36.7% for children with ASC following treatment, compared to up to 20.6% and 21.3% recovery in waitlist and active treatment comparisons. 

The lack of consistency in diagnostic outcomes highlights the urgent need for consensus on reporting in future RCTs of childhood anxiety disorders for the meaningful synthesis of data going forwards. 

Copyright &copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Warwick, Helen. School of Psychology and Clinical Language Sciences, University of Reading, UK. Reardon, Tessa. School of Psychology and Clinical Language Sciences, University of Reading, UK. Electronic address: t.c.reardon@pgr.reading.ac.uk. Cooper, Peter. School of Psychology and Clinical Language Sciences, University of Reading, UK; Department of Psychology, Stellenbosch University, South Africa; Department of Psychology, University of Cape Town, South Africa. Murayama, Kou. School of Psychology and Clinical Language Sciences, University of Reading, UK. Reynolds, Shirley. School of Psychology and Clinical Language Sciences, University of Reading, UK. Wilson, Charlotte. Department of Psychology, Trinity College, Dublin, Ireland. Creswell, Cathy. School of Psychology and Clinical Language Sciences, University of Reading, UK.
AN  - 28040627
AU  - Warwick,
AU  - H.
AU  - Reardon,
AU  - T.
AU  - Cooper,
AU  - P.
AU  - Murayama,
AU  - K.
AU  - Reynolds,
AU  - S.
AU  - Wilson,
AU  - C.
AU  - Creswell,
AU  - C.
DA  - Dec 21
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2016.12.002
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://3282561109/Warwick-2016-Complete recovery from anxiety di.pdf
LA  - English
M3  - Review
N1  - Warwick, Helen Reardon, Tessa Cooper, Peter Murayama, Kou Reynolds, Shirley Wilson, Charlotte Creswell, Cathy S0272-7358(15)30180-X
PY  - 2016
SP  - 77-91
T2  - Clinical Psychology Review
TI  - Complete recovery from anxiety disorders following Cognitive Behavior Therapy in children and adolescents: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28040627http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28040627&amp;id=doi:10.1016%2Fj.cpr.2016.12.002&amp;issn=0272-7358&amp;isbn=&amp;volume=52&amp;issue=&amp;spage=77&amp;pages=77-91&amp;date=2016&amp;title=Clinical+Psychology+Review&amp;atitle=Complete+recovery+from+anxiety+disorders+following+Cognitive+Behavior+Therapy+in+children+and+adolescents%3A+A+meta-analysis.&amp;aulast=Warwick&amp;pid=%3Cauthor%3EWarwick+H%3C%2Fauthor%3E%3CAN%3E28040627%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S027273581530180X/1-s2.0-S027273581530180X-main.pdf?_tid=c886e03e-04d1-11e7-8d26-00000aab0f26&amp;acdnat=1489068651_2d6e3a1381775506a85f1dc6e56283df
VL  - 52
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
Aripiprazole (ARP) has been shown to be effective in the treatment of bipolar disorder (BD). However, no prior investigation considered both randomized clinical trials (RCTs) and non-RCTs. We here evaluated the efficacy and safety of ARP compared with placebo (PCB) and other drugs at 3- and 12-weeks in adult and pediatric population including, for the first time, both observational and controlled studies. 

**METHODS: **
All studies were systematically located by searching electronic sources (EMBASE, MEDLINE, CINHAIL, PsychINFO, Cochrane Central Register of Controlled Trials, Scopus and ClinicalTrials.gov) till June 30th, 2015. The primary outcome was ARP efficacy (mean change from baseline in Young Mania Rating Scale); secondary outcomes regarded acceptability and safety. Results Sixteen RCTs and 6 non-RCTs met our inclusion criteria; 2505 and 2932 patients were included in the analyses of acute and stabilization phase, respectively. In both the acute and stabilization phases ARP efficacy was superior to PCB and comparable to other drugs. The safety profile was similar to other drugs considering in particular sedation, akathisia, weight gain, extrapyramidal and gastroenteric symptoms, with a significant lower risk of hyperprolactinemia particularly at 12-weeks. 

**LIMITATIONS:**
Data on failed trials are generally limited. 

**CONCLUSIONS: **
ARP resulted to be an effective treatment in children and adults with BD at 3- and 12-weeks both in a controlled experimental setting or in the real world clinical practice, being poorly associated with hyperprolactinemia. Larger studies are needed to confirm our results related to the maintenance phases and to the pediatric bipolar population.

Copyright &copy; 2015 Elsevier B.V. All rights reserved.
AD  - Meduri, Martina. Department of Experimental and Clinical Medical Sciences, ICBN, University of Udine, Udine, Italy. Gregoraci, Giorgia. Department of Biological and Medical Sciences, University of Udine, Udine, Italy. Baglivo, Valentina. Department of Experimental and Clinical Medical Sciences, ICBN, University of Udine, Udine, Italy. Balestrieri, Matteo. Department of Experimental and Clinical Medical Sciences, ICBN, University of Udine, Udine, Italy. Isola, Miriam. Department of Biological and Medical Sciences, University of Udine, Udine, Italy. Brambilla, Paolo. Department of Neurosciences and Mental Health, Psychiatric Clinic, Fondazione IRCCS Ca&#039;Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy; Department of Psychiatry and Behavioural Sciences, University of Texas Health Science Center at Houston, TX, USA. Electronic address: paolo.brambilla1@unimi.it.
AN  - 26674213
AU  - Meduri,
AU  - M.
AU  - Gregoraci,
AU  - G.
AU  - Baglivo,
AU  - V.
AU  - Balestrieri,
AU  - M.
AU  - Isola,
AU  - M.
AU  - Brambilla,
AU  - P.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jad.2015.11.033
DP  - Ovid Technologies
J2  - J Affect Disord
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Akathisia, Drug-Induced/et [Etiology]
KW  - *Antipsychotic Agents/tu [Therapeutic Use]
KW  - *Aripiprazole/tu [Therapeutic Use]
KW  - Basal Ganglia Diseases/ci [Chemically Induced]
KW  - *Bipolar Disorder/dt [Drug Therapy]
KW  - Child
KW  - Gastrointestinal Diseases/ci [Chemically Induced]
KW  - Humans
KW  - Hyperprolactinemia/ci [Chemically Induced]
KW  - Male
KW  - Middle Aged
KW  - Observational Studies as Topic
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
KW  - Weight Gain
KW  - Young Adult
KW  - 0 (Antipsychotic Agents)
KW  - 82VFR53I78 (Aripiprazole)
L1  - internal-pdf://3228203468/Meduri-2016-A meta-analysis of efficacy and sa.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural
N1  - Meduri, Martina Gregoraci, Giorgia Baglivo, Valentina Balestrieri, Matteo Isola, Miriam Brambilla, Paolo S0165-0327(15)30775-8
PY  - 2016
SP  - 187-208
T2  - Journal of Affective Disorders
TI  - A meta-analysis of efficacy and safety of aripiprazole in adult and pediatric bipolar disorder in randomized controlled trials and observational studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26674213http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26674213&amp;id=doi:10.1016%2Fj.jad.2015.11.033&amp;issn=0165-0327&amp;isbn=&amp;volume=191&amp;issue=&amp;spage=187&amp;pages=187-208&amp;date=2016&amp;title=Journal+of+Affective+Disorders&amp;atitle=A+meta-analysis+of+efficacy+and+safety+of+aripiprazole+in+adult+and+pediatric+bipolar+disorder+in+randomized+controlled+trials+and+observational+studies.&amp;aulast=Meduri&amp;pid=%3Cauthor%3EMeduri+M%3C%2Fauthor%3E%3CAN%3E26674213%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0165032715307758/1-s2.0-S0165032715307758-main.pdf?_tid=9e83d954-04cc-11e7-913a-00000aacb361&amp;acdnat=1489066433_fd6c228f937bfc8370851498b4532231
VL  - 191
ER  -
TY  - JOUR
AB  - **Background:** 
The increased birth rate of twins during recent decades and the improved prognosis of preterm infants have resulted in the need to explore measures that could optimize their growth and neurodevelopmental outcomes. It has been postulated that co-bedding simulates twins&#039; intrauterine experiences in which co-regulatory behaviors between them are observed. These behaviors are proposed to benefit twins by reducing their stress, which may promote growth and development. However, in practice, uncertainty surrounds the benefit-risk profile of co-bedding.

**Objectives:** 
We aimed to assess the effectiveness of co-bedding compared with separate (individual) care for stable preterm twins in the neonatal nursery in promoting growth and neurodevelopment and reducing short- and long-term morbidities, and to determine whether co-bedding is associated with significant adverse effects.As secondary objectives, we sought to evaluate effects of co-bedding via the following subgroup analyses: twin pairs with different weight ranges (very low birth weight [VLBW] &lt; 1500 grams vs non-VLBW), twins with versus without significant growth discordance at birth, preterm versus borderline preterm twins, twins co-bedded in incubator versus cot at study entry, and twins randomized by twin pair versus neonatal unit.

**Search methods:** 
We used the standard search strategy of the Cochrane Neonatal Review Group (CNRG). We used keywords and medical subject headings (MeSH) to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 2), MEDLINE (via PubMed), EMBASE (hosted by EBSCOHOST), the Cumulative Index to Nursing and Allied Health Literature (CINAHL), and references cited in our short-listed articles, up to February 29, 2016.

**Selection criteria:** 
We included randomized controlled trials with randomization by twin pair and/or by neonatal unit. We excluded cross-over studies.

**Data collection and analysis:** 
We extracted data using standard methods of the CNRG. Two review authors independently assessed the relevance and risk of bias of retrieved records. We contacted the authors of included studies to request important information missing from their published papers. We expressed our results using risk ratios (RRs) and mean differences (MDs) when appropriate, along with 95% confidence intervals (95% CIs). We adjusted the unit of analysis from individual infants to twin pairs by averaging measurements for each twin pair (continuous outcomes) or by counting outcomes as positive if developed by either twin (dichotomous outcomes).

**Main results:** 
Six studies met the inclusion criteria; however, only five studies provided data for analysis. Four of the six included studies were small and had significant limitations in design. As each study reported outcomes differently, data for most outcomes were effectively contributed by a single study. Study authors reported no differences between co-bedded twins and twins receiving separate care in terms of rate of weight gain (MD 0.20 grams/kg/d, 95% CI -1.60 to 2.00; one study; 18 pairs of twins; evidence of low quality); apnea, bradycardia, and desaturation (A/B/D) episodes (RR 0.85, 95% CI 0.18 to 4.05; one study; 62 pairs of twins; evidence of low quality); episodes in co-regulated states (MD 0.96, 95% CI -3.44 to 5.36; one study; three pairs of twins; evidence of very low quality); suspected or proven infection (RR 0.84, 95% CI 0.30 to 2.31; three studies; 65 pairs of twins; evidence of very low quality); length of hospital stay (MD -4.90 days, 95% CI -35.23 to 25.43; one study; three pairs of twins; evidence of very low quality); and parental satisfaction measured on a scale of 0 to 55 (MD -0.38, 95% CI -4.49 to 3.73; one study; nine pairs of twins; evidence of moderate quality). Although co-bedded twins appeared to have lower pain scores 30 seconds after heel lance on a scale of 0 to 21 (MD -0.96, 95% CI -1.68 to -0.23; two studies; 117 pairs of twins; I2 = 75%; evidence of low quality), they had higher pain scores 90 seconds after the procedure (MD 1.00, 95% CI 0.14 to 1.86; one study; 62 pa r of twins). Substantial heterogeneity in the outcome of infant pain response after heel prick at 30 seconds post procedure and conflicting results at 30 and 90 seconds post procedure precluded clear conclusions.

**Authors&#039; conclusions:** 
Evidence on the benefits and harms of co-bedding for stable preterm twins was insufficient to permit recommendations for practice. Future studies must be adequately powered to detect clinically important differences in growth and neurodevelopment. Researchers should assess harms such as infection, along with medication errors and caregiver satisfaction.
AN  - CD008313
AU  - Lai,
AU  - N.
AU  - M.
AU  - Foong,
AU  - S.
AU  - C.
AU  - Foong,
AU  - W.
AU  - C.
AU  - Tan,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd008313.pub3
KW  - Beds
KW  - Twins
KW  - Child Development [physiology]
KW  - Infant Care [methods]
KW  - Infant, Premature [growth &amp; development]
KW  - Intensive Care Units, Neonatal
KW  - Randomized Controlled Trials as Topic
KW  - Humans[checkword]
KW  - Infant, Newborn[checkword]
KW  - Neonatal
L1  - internal-pdf://1958258261/5ebf75fe21d5c3147ee361b809501b6915bd3c09e11655.pdf
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Co-bedding in neonatal nursery for promoting growth and neurodevelopment in stable preterm twins
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008313.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD008313.pub3/asset/CD008313.pdf?v=1&amp;t=iw7j39iq&amp;s=19a0e3a42ea1c0d3f89763c243ff5b1a1deb65dc
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
Clinicians utilise critical research to advance their knowledge when prescribing standard and alternative therapies for developmental disorders. Recent research has reported that the traditional Ayurvedic medicine Bacopa monnieri may improve cognitive outcomes in adult populations; however, few studies have investigated its benefits in younger cohorts. The aim of the current review is to systematically assess and critically summarize clinical trial outcomes and safety of Bacopa and its effects on the cognition and behaviour in children and adolescents. 

**METHOD: **
PubMed, Scopus, Cochrane Library, Google and CINAHL were searched up to August 2015 for trials investigating Bacopa monnieri in child and adolescent populations. There were no restrictions in study design. Cognitive and behavioural outcomes were grouped into validated constructs and effect sizes were calculated for all significant data to allow for direct comparisons. 

**RESULTS: **
Five studies met inclusion criteria for this review. The results demonstrated significant consistent improvements in the language behaviour cognitive domain and in a number of the memory sub-domains. Significant improvements were also seen in hyperactivity and attention-deficit domains. Overall outcome data demonstrated small to medium effect sizes (mean d=0.42). Safety and tolerability data was well reported for 80% of studies with only 2.3% of all participants reporting mild side-effects. 

**CONCLUSION: **
This review highlights the safe use of Bacopa monnieri in child and adolescent populations for improving elements of cognition as well as behaviour and attention-deficit domains. However, there is a significant need for replicated study designs and stringent statistical analysis to validate these outcomes. 

Copyright A&copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Kean, James D. Centre for Human Psychopharmacology, Swinburne University, Melbourne, Australia. Electronic address: jkean@swin.edu.au. Downey, Luke A. Centre for Human Psychopharmacology, Swinburne University, Melbourne, Australia; Department of Psychology, Swansea University, Swansea, Wales, UK. Stough, Con. Centre for Human Psychopharmacology, Swinburne University, Melbourne, Australia.
AN  - 27912958
AU  - Kean,
AU  - J.
AU  - D.
AU  - Downey,
AU  - L.
AU  - A.
AU  - Stough,
AU  - C.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ctim.2016.09.002
DP  - Ovid Technologies
J2  - Complement Ther Med
L1  - internal-pdf://1433476889/Kean-2016-A systematic review of the Ayurvedic.pdf
LA  - English
M3  - Review
N1  - Kean, James D Downey, Luke A Stough, Con S0965-2299(16)30138-8
PY  - 2016
SP  - 56-62
T2  - Complementary Therapies in Medicine
TI  - A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27912958http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27912958&amp;id=doi:10.1016%2Fj.ctim.2016.09.002&amp;issn=0965-2299&amp;isbn=&amp;volume=29&amp;issue=&amp;spage=56&amp;pages=56-62&amp;date=2016&amp;title=Complementary+Therapies+in+Medicine&amp;atitle=A+systematic+review+of+the+Ayurvedic+medicinal+herb+Bacopa+monnieri+in+child+and+adolescent+populations.&amp;aulast=Kean&amp;pid=%3Cauthor%3EKean+JD%3C%2Fauthor%3E%3CAN%3E27912958%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0965229916301388/1-s2.0-S0965229916301388-main.pdf?_tid=a5b604d4-04c9-11e7-ba5c-00000aab0f26&amp;acdnat=1489065157_2191bd132e1bb26b4a995c9b058e5117
VL  - 29
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) in childhood and adulthood is often treated with the psychostimulant methylphenidate (MPH). However, it is unknown whether cognitive effects of MPH depend on age in individuals with ADHD, while animal studies have suggested age-related effects. 

In this meta-analysis, we first determined the effects of MPH on response inhibition, working memory and sustained attention, but our main goal was to examine whether these effects are moderated by age. 

A systematic literature search using PubMed, PsycINFO, Web of Science and MEDLINE for double-blind, placebo-controlled studies with MPH resulted in 25 studies on response inhibition (n = 775), 13 studies on working memory (n = 559) and 29 studies on sustained attention (n = 956) (mean age range 4.8-50.1 years). The effects of MPH on response inhibition [effect size (ES) = 0.40, p &lt; 0.0001, 95% confidence interval (CI) 0.22-0.58], working memory (ES = 0.24, p = 0.053, 95% CI 0.00-0.48) and sustained attention (ES = 0.42, p &lt; 0.0001, 95% CI 26-0.59) were small to moderate. 

No linear or quadratic age-dependencies were observed, indicating that effects of MPH on executive functions are independent of age in children and adults with ADHD. However, adolescent studies are lacking and needed to conclude a lack of an age-dependency across the lifespan.
AN  - 27019103
AU  - Tamminga,
AU  - H.
AU  - G.
AU  - Reneman,
AU  - L.
AU  - Huizenga,
AU  - H.
AU  - M.
AU  - Geurts,
AU  - H.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1017/S0033291716000350
L1  - internal-pdf://4007045907/Tamminga-2016-Effects of methylphenidate on ex.pdf
PY  - 2016
SP  - 1791-807
T2  - Psychological Medicine
TI  - Effects of methylphenidate on executive functioning in attention-deficit/hyperactivity disorder across the lifespan: a meta-regression analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=27019103
UR  - https://www.cambridge.org/core/journals/psychological-medicine/article/effects-of-methylphenidate-on-executive-functioning-in-attentiondeficithyperactivity-disorder-across-the-lifespan-a-metaregression-analysis/30CA026CB81CE74D7C73E92F171710F5
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/30CA026CB81CE74D7C73E92F171710F5/S0033291716000350a.pdf/div-class-title-effects-of-methylphenidate-on-executive-functioning-in-attention-deficit-hyperactivity-disorder-across-the-lifespan-a-meta-regression-analysis-div.pdf
VL  - 46
ER  -
TY  - JOUR
AB  - The large number of studies published in recent years aimed at evaluating the effectiveness of school-based anti-bullying programs recommends research to focus on synthesizing the evidence found in this regard. 

This study presents a meta-analysis of random clinical trials that assess the efficacy of 14 anti-bullying school programs. Sample size was of 30,934 adolescents aged between 7 and 16 years of whom 16,243 made up the Intervention Groups and 14,691 made up the Control Groups. Meta-analysis was conducted for each outcome measure, as well as heterogeneity analysis. Analysis of subgroups was performed when necessary, as well as analysis of publication bias. 

Results show moderate effect sizes for the outcome measures Bullying Frequency and Victimization Frequency, Attitudes and School Climate. Greater impact was observed in interventions of less than one school year duration, as well as those targeting children younger than 10years. 

Subgroup analysis confirmed greater heterogeneity in studies evaluating complex interventions. In general, our results indicate that bullying and violence prevention programs in school settings are obtaining beneficial, albeit discrete, results in the outcome measures evaluated. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Jimenez-Barbero, Jose Antonio: barbero49@hotmail.com; Ruiz-Hernandez, Jose Antonio: jaruiz@um.es; Llor-Zaragoza, Laura: llorzaragoza@ucam.edu; Perez-Garcia, Maria: mariapg78@hotmail.com; Llor-Esteban, Bartolome: bllor@um.es Jimenez-Barbero, Jose Antonio, Plaza Vistabella, 17, 2L, Alcantarilla, Murcia, Spain, CP: 30820, barbero49@hotmail.com Jimenez-Barbero, Jose Antonio: University of Murcia, Faculty of Psychology, Murcia, Spain Ruiz-Hernandez, Jose Antonio: University of Murcia, Faculty of Psychology, Murcia, Spain Llor-Zaragoza, Laura: Catholic University San Antonio, Faculty of Social Sciences and Communication, Murcia, Spain Perez-Garcia, Maria: Mental Health Center of Cieza, Murcia, Spain Llor-Esteban, Bartolome: University of Murcia, Faculty of Psychology, Murcia, Spain
AN  - 2016-06173-022
AU  - Jimenez-Barbero,
AU  - J.
AU  - A.
AU  - Ruiz-Hernandez,
AU  - J.
AU  - A.
AU  - Llor-Zaragoza,
AU  - L.
AU  - Perez-Garcia,
AU  - M.
AU  - Llor-Esteban,
AU  - B.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2015.12.015
DP  - Ovid Technologies
KW  - Bullying, Violence, Adolescents, School program, Effectiveness, Meta-analysis
KW  - *Victimization
KW  - *Violence
KW  - *Bullying
KW  - School Based Intervention
KW  - Schools
KW  - Behavior Disorders &amp; Antisocial Behavior [3230]
KW  - Human Childhood (birth-12 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://1117198294/Jimenez-2016-Effectiveness of anti-bullying sc.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 165-175
T2  - Children and Youth Services Review
TI  - Effectiveness of anti-bullying school programs: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-06173-022http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2015.12.015&amp;issn=0190-7409&amp;isbn=&amp;volume=61&amp;issue=&amp;spage=165&amp;pages=165-175&amp;date=2016&amp;title=Children+and+Youth+Services+Review&amp;atitle=Effectiveness+of+anti-bullying+school+programs%3A+A+meta-analysis.&amp;aulast=Jimenez-Barbero&amp;pid=%3Cauthor%3EJimenez-Barbero%2C+Jose+Antonio%3C%2Fauthor%3E%3CAN%3E2016-06173-022%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0190740915301286/1-s2.0-S0190740915301286-main.pdf?_tid=33139d88-04c9-11e7-bf12-00000aacb35d&amp;acdnat=1489064965_c588b21b1b6c97751cc588a76d8f7d02
VL  - 61
ER  -
TY  - JOUR
AB  - The quantitative literature on the treatment of comorbid depression and substance misuse among adolescents was reviewed, including: (1) a synthesis of the empirical evidence of the multiple models of integrated treatment for depression and substance use, (2) an examination of proposed mechanisms underlying symptom change in these integrated treatment models targeting depression and substance use, and (3) a methodological critique and suggestions for future research. 

We reviewed 15 studies reporting on treatment outcomes among adolescents with comorbid depression and non-tobacco related substance use disorders (SUD) and general misuse. 

Although there is empirical evidence linking Cognitive-Behavioral Therapy (CBT), Motivational Enhancement Therapy (MET), and Family-Focused Therapy (FFT) to depression and SUD symptom reduction in adolescents, few studies have provided data on mechanisms that may account for this effect. 

Potential mechanisms include improvements in dysfunctional reward processing and self-efficacy. Although this review highlights promising findings for the treatment of comorbid depression and substance misuse in adolescents, further work is warranted; as such results could have important implications for intervention development.
AD  - Babowitch, Jacklyn D. Syracuse University, United States. Electronic address: jdbabowi@syr.edu. Antshel, Kevin M. Syracuse University, United States.
AN  - 27156096
AU  - Babowitch,
AU  - J.
AU  - D.
AU  - Antshel,
AU  - K.
AU  - M.
DA  - Sep 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jad.2016.04.018
DP  - Ovid Technologies
J2  - J Affect Disord
L1  - internal-pdf://1015710847/Babowitch-2016-Adolescent treatment outcomes f.pdf
LA  - English
M3  - Review
N1  - Babowitch, Jacklyn D Antshel, Kevin M S0165-0327(16)30069-6
PY  - 2016
SP  - 25-33
T2  - Journal of Affective Disorders
TI  - Adolescent treatment outcomes for comorbid depression and substance misuse: A systematic review and synthesis of the literature
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27156096http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27156096&amp;id=doi:10.1016%2Fj.jad.2016.04.018&amp;issn=0165-0327&amp;isbn=&amp;volume=201&amp;issue=&amp;spage=25&amp;pages=25-33&amp;date=2016&amp;title=Journal+of+Affective+Disorders&amp;atitle=Adolescent+treatment+outcomes+for+comorbid+depression+and+substance+misuse%3A+A+systematic+review+and+synthesis+of+the+literature.&amp;aulast=Babowitch&amp;pid=%3Cauthor%3EBabowitch+JD%3C%2Fauthor%3E%3CAN%3E27156096%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0165032716300696/1-s2.0-S0165032716300696-main.pdf?_tid=f769296c-04c1-11e7-b206-00000aacb362&amp;acdnat=1489061858_f8f1b6aedcc84352847b45acb58a8716
VL  - 201
ER  -
TY  - JOUR
AB  - The present study aimed to review recent literature on universal violence and child maltreatment prevention programs for parents. The following databases were used: Web of Science, PsycINFO, PsycARTICLES, PubMed, LILACS, and SciELO. The keywords included the following: (Parenting Program or Parent Training or Parent Intervention) and (Maltreatment or Violence or Violence Prevention). 

For inclusion in this review, the programs had to be structured, working in groups of parents aiming to improve patenting practices. Twenty-three studies were included, and 16 different types of parenting programs were identified. Ninety-one percent of the studies were conducted in developed countries. All the programs focused on the prevention of violence and maltreatment by promoting positive parenting practices. 

Only seven studies were randomized controlled trials. All studies that evaluated parenting strategies (n = 18), reported after the interventions. The programs also effectively improved child behavior in 90% of the studies that assessed this outcome. In conclusion, parenting educational programs appear to be an important strategy for the universal prevention of violence and maltreatment against children. 

Future studies should assess the applicability and effectiveness of parenting programs for the prevention of violence against children in developing countries. Further randomized control trials are also required. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2016-21032-004
AU  - Altafim,
AU  - E.
AU  - R.
AU  - P.
AU  - Linhares,
AU  - M.
AU  - B.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.psi.2015.10.003
L1  - internal-pdf://0140703769/Altafim-2016-Universal violence and child malt.pdf
PY  - 2016
SP  - 27-38
TI  - Universal violence and child maltreatment prevention programs for parents: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-21032-004
VL  - 25
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Substance use has detrimental short-term and long-term consequences for young people. Positive youth development (PYD) interventions, which favour promotion of positive assets over traditional risk reduction, have received attention recently as a possible intervention to prevent adolescent substance use. We aimed to synthesise the evidence on PYD interventions for reduction in substance use in young people. 

**METHODS: **
We searched 21 databases, including MEDLINE, PsycINFO, CINAHL and CENTRAL, and hand-searched key journals and websites. We included studies with more than half of participants aged 11-18 years where interventions meeting a pre-specified definition of PYD were delivered in community settings outside of normal school hours and did not target parents or young people with pre-defined conditions. Two reviewers screened records, assessed full-text studies for inclusion, and extracted data. A modified Cochrane risk of bias tool was used for quality assessment. 

**RESULTS: **
Ten studies reported in 13 reports were included in our synthesis. PYD interventions did not have an effect of statistical or public health significance on any substance use, illicit drug use or alcohol outcomes in young people. 

**CONCLUSIONS: **
Interventions were diverse in content and delivery. Our review suggests that existing PYD interventions subject to evaluation do not appear to have produced reductions in substance use of public health significance. However, these interventions may not be the best exemplars of a PYD approach. Therefore, our findings should not be taken as evidence for the ineffectiveness of PYD as a theory of change for reducing substance use among young people. Additional rigorous evaluation of PYD interventions is key before further investment. Evaluations were of highly variable quality. Though searches were extensive, we were unable to test for publication bias. 

Copyright &copy; 2016 Elsevier B.V. All rights reserved.
AD  - Melendez-Torres, G J. Warwick Evidence, Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK. Electronic address: G.Melendez-Torres@warwick.ac.uk. Dickson, Kelly. Evidence for Policy and Practice Information and Co-ordinating Centre (EPPI-Centre), UCL Institute of Education, University College London, London, UK. Fletcher, Adam. DECIPHer, School of Social Sciences, Cardiff University, Cardiff, UK. Thomas, James. Evidence for Policy and Practice Information and Co-ordinating Centre (EPPI-Centre), UCL Institute of Education, University College London, London, UK. Hinds, Kate. Evidence for Policy and Practice Information and Co-ordinating Centre (EPPI-Centre), UCL Institute of Education, University College London, London, UK. Campbell, Rona. DECIPHer, School of Social and Community Medicine, University of Bristol, Bristol, UK. Murphy, Simon. DECIPHer, School of Social Sciences, Cardiff University, Cardiff, UK. Bonell, Chris. Evidence for Policy and Practice Information and Co-ordinating Centre (EPPI-Centre), UCL Institute of Education, University College London, London, UK.
AN  - 26874990
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Dickson,
AU  - K.
AU  - Fletcher,
AU  - A.
AU  - Thomas,
AU  - J.
AU  - Hinds,
AU  - K.
AU  - Campbell,
AU  - R.
AU  - Murphy,
AU  - S.
AU  - Bonell,
AU  - C.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.drugpo.2016.01.007
DP  - Ovid Technologies
J2  - Int J Drug Policy
L1  - internal-pdf://3374807828/Melendez-2016-Positive youth development progr.pdf
LA  - English
N1  - Melendez-Torres, G J Dickson, Kelly Fletcher, Adam Thomas, James Hinds, Kate Campbell, Rona Murphy, Simon Bonell, Chris S0955-3959(16)00030-X
PY  - 2016
SP  - 95-103
T2  - International Journal of Drug Policy
TI  - Positive youth development programmes to reduce substance use in young people: Systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26874990http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26874990&amp;id=doi:10.1016%2Fj.drugpo.2016.01.007&amp;issn=0955-3959&amp;isbn=&amp;volume=36&amp;issue=&amp;spage=95&amp;pages=95-103&amp;date=2016&amp;title=International+Journal+of+Drug+Policy&amp;atitle=Positive+youth+development+programmes+to+reduce+substance+use+in+young+people%3A+Systematic+review.&amp;aulast=Melendez-Torres&amp;pid=%3Cauthor%3EMelendez-Torres+GJ%3C%2Fauthor%3E%3CAN%3E26874990%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S095539591600030X/1-s2.0-S095539591600030X-main.pdf?_tid=b3b98468-04cc-11e7-bef2-00000aacb35e&amp;acdnat=1489066469_5916a4b522febd426bbaebbb41bdc66f
VL  - 36
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
To determine the effectiveness of primary health care relevant interventions to prevent and treat tobacco smoking in school-aged children and adolescents. 

**METHODS: **
This systematic review considered studies included in a prior review. We adapted and updated the search to April 2015. Titles, abstracts and full-text articles were reviewed in duplicate; data extraction and quality assessments were performed by one reviewer and verified by another. Meta-analyses and pre-specified sub-group analyses were performed when possible. PROSPERO #CRD42015019051. 

**RESULTS: **
After screening 2118 records, we included nine randomized controlled trials. The mostly moderate quality evidence suggested targeted behavioral interventions can prevent smoking and assist with cessation. Meta-analysis showed intervention participants were 18% less likely to report having initiated smoking at the end of intervention relative to controls (Risk Ratio 0.82; 95% confidence interval 0.72, 0.94); the absolute effect is 1.92% for smoking initiation, Number Needed to Treat is 52 (95% confidence interval 33, 161). For cessation, meta-analysis showed intervention participants were 34% more likely to report having quit smoking at the end of intervention relative to controls (Risk Ratio 1.34; 95% confidence interval 1.05, 1.69); the absolute effect is 7.98% for cessation, Number Needed to Treat is 13 (95% confidence interval 6, 77). Treatment harms were not mentioned in the literature and no data were available to assess long-term effectiveness. 

**CONCLUSION: **
Primary care relevant behavioral interventions improve smoking outcomes for children and youth. The evidence on key components is limited by heterogeneity in methodology and intervention strategy. Future trials should target tailored prevention or treatment approaches, establish uniform definition and measurement of smoking, isolate optimal intervention components, and include long-term follow-up. 

Copyright &copy; 2015 Elsevier Inc. All rights reserved.
AD  - Peirson, Leslea. McMaster Evidence Review and Synthesis Centre, McMaster University, 1280 Main St. W., McMaster Innovation Park, Room 207A, Hamilton, Ontario L8S 4K1, Canada; School of Nursing, Faculty of Health Sciences, McMaster University, Health Sciences Centre Room HSC-3N25F, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada. Electronic address: peirson@mcmaster.ca. Ali, Muhammad Usman. McMaster Evidence Review and Synthesis Centre, McMaster University, 1280 Main St. W., McMaster Innovation Park, Room 207A, Hamilton, Ontario L8S 4K1, Canada; Department of Clinical Epidemiology &amp; Biostatistics, Faculty of Health Sciences, McMaster University, Room HSC-2C, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada. Electronic address: aliu@mcmaster.ca. Kenny, Meghan. McMaster Evidence Review and Synthesis Centre, McMaster University, 1280 Main St. W., McMaster Innovation Park, Room 207A, Hamilton, Ontario L8S 4K1, Canada; Department of Clinical Epidemiology &amp; Biostatistics, Faculty of Health Sciences, McMaster University, Room HSC-2C, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada. Electronic address: mkenny@mcmaster.ca. Raina, Parminder. McMaster Evidence Review and Synthesis Centre, McMaster University, 1280 Main St. W., McMaster Innovation Park, Room 207A, Hamilton, Ontario L8S 4K1, Canada; Department of Clinical Epidemiology &amp; Biostatistics, Faculty of Health Sciences, McMaster University, Room HSC-2C, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada. Electronic address: praina@mcmaster.ca. Sherifali, Diana. McMaster Evidence Review and Synthesis Centre, McMaster University, 1280 Main St. W., McMaster Innovation Park, Room 207A, Hamilton, Ontario L8S 4K1, Canada; School of Nursing, Faculty of Health Sciences, McMaster University, Health Sciences Centre Room HSC-3N25F, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada. Electronic address: dsherif@mcmaster.ca.
AN  - 26743631
AU  - Peirson,
AU  - L.
AU  - Ali,
AU  - M.
AU  - U.
AU  - Kenny,
AU  - M.
AU  - Raina,
AU  - P.
AU  - Sherifali,
AU  - D.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ypmed.2015.12.004
DP  - Ovid Technologies
J2  - Prev Med
KW  - Adolescent
KW  - *Behavior Therapy/mt [Methods]
KW  - Child
KW  - Humans
KW  - *Primary Health Care/mt [Methods]
KW  - Randomized Controlled Trials as Topic
KW  - *Smoking/pc [Prevention &amp; Control]
KW  - *Smoking Cessation/mt [Methods]
L1  - internal-pdf://2053021026/Peirson-2016-Interventions for prevention and.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Peirson, Leslea Ali, Muhammad Usman Kenny, Meghan Raina, Parminder Sherifali, Diana S0091-7435(15)00377-1
PY  - 2016
SP  - 20-31
T2  - Preventive Medicine
TI  - Interventions for prevention and treatment of tobacco smoking in school-aged children and adolescents: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26743631http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26743631&amp;id=doi:10.1016%2Fj.ypmed.2015.12.004&amp;issn=0091-7435&amp;isbn=&amp;volume=85&amp;issue=&amp;spage=20&amp;pages=20-31&amp;date=2016&amp;title=Preventive+Medicine&amp;atitle=Interventions+for+prevention+and+treatment+of+tobacco+smoking+in+school-aged+children+and+adolescents%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Peirson&amp;pid=%3Cauthor%3EPeirson+L%3C%2Fauthor%3E%3CAN%3E26743631%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0091743515003771/1-s2.0-S0091743515003771-main.pdf?_tid=fdc1d7ee-04cd-11e7-b0c3-00000aacb35e&amp;acdnat=1489067023_01dbc5ea342b96708bd616ad084a5ac2
VL  - 85
ER  -
TY  - JOUR
AB  - **Background:** 
Depression is common in young people. It has a marked negative impact and is associated with self-harm and suicide. Preventing its onset would be an important advance in public health. This is an update of a Cochrane review that was last updated in 2011.

**Objectives:** 
To determine whether evidence-based psychological interventions (including cognitive behavioural therapy (CBT), interpersonal therapy (IPT) and third wave CBT)) are effective in preventing the onset of depressive disorder in children and adolescents.

**Search methods:** 
We searched the specialised register of the Cochrane Common Mental Disorders Group (CCMDCTR to 11 September 2015), which includes relevant randomised controlled trials from the following bibliographic databases: The Cochrane Library (all years), EMBASE (1974 to date), MEDLINE (1950 to date) and PsycINFO (1967 to date). We searched conference abstracts and reference lists of included trials and reviews, and contacted experts in the field.

**Selection criteria:** 
We included randomised controlled trials of an evidence-based psychological prevention programme compared with any comparison control for young people aged 5 to 19 years, who did not currently meet diagnostic criteria for depression.

**Data collection and analysis:** 
Two authors independently assessed trials for inclusion and rated their risk of bias.&nbsp;We adjusted sample sizes to take account of cluster designs and multiple comparisons. We contacted trial authors for additional information where needed.&nbsp;We assessed the quality of evidence for the primary outcomes using GRADE.

**Main results:** 
We included 83 trials in this review. The majority of trials (67) were carried out in school settings with eight in colleges or universities, four in clinical settings, three in the community and four in mixed settings. Twenty-nine trials were carried out in unselected populations and 53 in targeted populations. For the primary outcome of depression diagnosis at medium-term follow-up (up to 12 months), there were 32 trials with 5965 participants and the risk of having a diagnosis of depression was reduced for participants receiving an intervention compared to those receiving no intervention (risk difference (RD) -0.03, 95% confidence interval (CI) -0.05 to -0.01; P value = 0.01). We rated this evidence as moderate quality according to the GRADE criteria. There were 70 trials (73 trial arms) with 13,829 participants that contributed to the analysis for the primary outcome of depression symptoms (self-rated) at the post-intervention time point, with results showing a small but statistically significant effect (standardised mean difference (SMD) -0.21, 95% CI -0.27 to -0.15; P value &lt; 0.0001). This effect persisted to the short-term assessment point (up to three months) (SMD -0.31, 95% CI -0.45 to -0.17; P value &lt; 0.0001; 16 studies; 1558 participants) and medium-term (4 to 12 months) assessment point (SMD -0.12, 95% CI -0.18 to -0.05; P value = 0.0002; 53 studies; 11,913 participants); however, the effect was no longer evident at the long-term follow-up. We rated this evidence as low to moderate quality according to the GRADE criteria.The evidence from this review is unclear with regard to whether the type of population modified the overall effects; there was statistically significant moderation of the overall effect for depression symptoms (P value = 0.0002), but not for depressive disorder (P value = 0.08). For trials implemented in universal populations there was no effect for depression diagnosis (RD -0.01, 95% CI -0.03 to 0.01) and a small effect for depression symptoms (SMD -0.11, 95% CI -0.17 to -0.05). For trials implemented in targeted populations there was a statistically significantly beneficial effect of intervention (depression diagnosis RD -0.04, 95% CI -0.07 to -0.01; depression symptoms SMD -0.32, 95% CI -0.42 to -0.23). Of note were the lack of attention placebo-controlled trials in targeted populations (none for depression diagnosis and four for depression symptoms). Among trials implemented in universal populations a number used an a t ntion placebo comparison in which the intervention consistently showed no effect.

**Authors&#039; conclusions:** 
Overall the results show small positive benefits of depression prevention, for both the primary outcomes of self-rated depressive symptoms post-intervention and depression diagnosis up to 12 months (but not beyond). Estimates of numbers needed to treat to benefit (NNTB = 11) compare well with other public health interventions. However, the evidence was of moderate to low quality using the GRADE framework and the results were heterogeneous. Prevention programmes delivered to universal populations showed a sobering lack of effect when compared with an attention placebo control. Interventions delivered to targeted populations, particularly those selected on the basis of depression symptoms, had larger effect sizes, but these seldom used an attention placebo comparison and there are practical difficulties inherent in the implementation of targeted programmes. We conclude that there is still not enough evidence to support the implementation of depression prevention programmes. Future research should focus on current gaps in our knowledge. Given the relative lack of evidence for universal interventions compared with attention placebo controls and the poor results from well-conducted effectiveness trials of universal interventions, in our opinion any future such trials should test a depression prevention programme in an indicated targeted population using a credible attention placebo comparison group. Depressive disorder as the primary outcome should be measured over the longer term, as well as clinician-rated depression. Such a trial should consider scalability as well as the potential for the intervention to do harm.
AN  - CD003380
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Cox,
AU  - G.
AU  - R.
AU  - Witt,
AU  - K.
AU  - G.
AU  - Bir,
AU  - J.
AU  - J.
AU  - Merry,
AU  - S.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003380.pub4
KW  - Depression [diagnosis] [prevention &amp; control]
KW  - Depressive Disorder [diagnosis] [prevention &amp; control]
KW  - Program Evaluation
KW  - Psychotherapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Young Adult[checkword]
KW  - Depressn
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive behavioural therapy (CBT), third-wave CBT and interpersonal therapy (IPT) based interventions for preventing depression in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003380.pub4/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003380.pub4/asset/CD003380.pdf?v=1&amp;t=iw7j3rxu&amp;s=d7fcdc7cf3b8fe1c8d4088d200025baf7fdbaed5
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
This systematic review evaluated the efficacy of universal, selective, and indicated eating disorder prevention. 

**METHOD: **
A systematic literature search was conducted in Medline, PsycINFO, Embase, Scopus, and the Cochrane Collaboration Library databases to January 2016. Studies were included if they were randomized, controlled trials (RCT) and tested an eating disorder prevention program. We retrieved 13 RCTs of universal prevention (N=3,989 participants, 55% female, M age=13.0 years), 85 RCTs of selective prevention (N=11,949 participants, 99% female, M age=17.6 years), and 8 RCTs of indicated prevention (N=510 participants, 100% female, M age=20.1 years). Meta-analysis was performed with selective prevention trials. As there were a limited number of universal and indicated trials, narrative synthesis was conducted. 

**RESULTS: **
Media literacy had the most support for universal prevention. Most universal approaches showed significant modest effects on risk factors. Dissonance-based was the best supported approach for selective prevention. Cognitive-behavior therapy (CBT), a healthy weight program, media literacy, and psychoeducation, were also effective for selective prevention and effects were maintained at follow-up. CBT was supported for indicated prevention and effects were maintained at follow-up.

**DISCUSSION: **
The modest effects for universal prevention were likely due to floor effects. The evidence for selective prevention suggests that empirically supported approaches should be disseminated on a wider basis. Our findings suggest CBT should be offered for indicated populations. Overall, results suggest efficacy of several prevention programs for reducing risk for eating disorders, and that wider dissemination is required. 

&copy; 2016 Wiley Periodicals, Inc. Copyright &copy; 2016 Wiley Periodicals, Inc.
AN  - 27425572
AU  - Watson,
AU  - H.
AU  - J.
AU  - Joyce,
AU  - T.
AU  - French,
AU  - E.
AU  - Willan,
AU  - V.
AU  - Kane,
AU  - R.
AU  - T.
AU  - Tanner-Smith,
AU  - E.
AU  - E.
AU  - McCormack,
AU  - J.
AU  - Dawkins,
AU  - H.
AU  - Hoiles,
AU  - K.
AU  - J.
AU  - Egan,
AU  - S.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/eat.22577
L1  - internal-pdf://2620627615/Watson-2016-Prevention of eating disorders_ A.pdf
PY  - 2016
SP  - 833-62
TI  - Prevention of eating disorders: A systematic review of randomized, controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med8&amp;AN=27425572
VL  - 49
ER  -
TY  - JOUR
AB  - A review of the effectiveness and potential harms of self-help groups in substance-misusing adolescents was performed. Twelve studies were examined. 

All studies were case series with important methodological shortcomings. The findings of these studies were summarized using a narrative synthesis approach. 

Results indicated that self-help group attendance appears to reduce alcohol and drug use, including abstinence. However, the lack of methodological rigor in these studies precludes definitive conclusions. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Bekkering, Geertruida E.: Trudy.bekkering@cebam.be Bekkering, Geertruida E.: CEBAM, Belgian Center for Evidence-Based Medicine, Kapucijnenvoer 33, blok j, Leuven, Belgium, 3000, Trudy.bekkering@cebam.be Bekkering, Geertruida E.: Faculty of Psychology and Education, University of Leuven, Leuven, Belgium Marien, Dorien: Faculty of Psychology and Education, University of Leuven, Leuven, Belgium Parylo, Oksana: Faculty of Psychology and Education, University of Leuven, Leuven, Belgium Hannes, Karin: Faculty of Psychology and Education, University of Leuven, Leuven, Belgium
AN  - 2016-16858-007
AU  - Bekkering,
AU  - G.
AU  - E.
AU  - Marien,
AU  - D.
AU  - Parylo,
AU  - O.
AU  - Hannes,
AU  - K.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/1067828X.2014.981772
DP  - Ovid Technologies
KW  - self-help, adolescent, substance, abuse, systematic review
KW  - *Drug Abuse
KW  - *Group Counseling
KW  - *Self-Help Techniques
KW  - *Treatment Effectiveness Evaluation
KW  - Drug &amp; Alcohol Rehabilitation [3383]
KW  - Human Adolescence (13-17 yrs)
L1  - internal-pdf://0222662118/Bekkering.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2016
SP  - 229-244
T2  - Journal of Child and Adolescent Substance Abuse
TI  - The effectiveness of self-help groups for adolescent substance misuse: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-16858-007http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F1067828X.2014.981772&amp;issn=1067-828X&amp;isbn=&amp;volume=25&amp;issue=3&amp;spage=229&amp;pages=229-244&amp;date=2016&amp;title=Journal+of+Child+%26+Adolescent+Substance+Abuse&amp;atitle=The+effectiveness+of+self-help+groups+for+adolescent+substance+misuse%3A+A+systematic+review.&amp;aulast=Bekkering&amp;pid=%3Cauthor%3EBekkering%2C+Geertruida+E%3C%2Fauthor%3E%3CAN%3E2016-16858-007%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 25
ER  -
TY  - JOUR
AB  - **Background:** 
Autism spectrum disorders (ASD) include autistic disorder, Asperger&#039;s disorder and pervasive developmental disorder - not otherwise specified (PDD-NOS). Antipsychotics have been used as a medication intervention for irritability related to ASD. Aripiprazole, a third-generation, atypical antipsychotic, is a relatively new drug that has a unique mechanism of action different from that of other antipsychotics. This review updates a previous Cochrane review on the safety and efficacy of aripiprazole for individuals with ASD, published in 2011 (Ching 2011).

**Objectives:** 
To assess the safety and efficacy of aripiprazole as medication treatment for individuals with ASD.

**Search methods:** 
In October 2015, we searched the Cochrane Central Register of Controlled Trials (CENTRAL), Ovid MEDLINE, Embase, the Cumulative Index to Nursing and Allied Health Literature (CINAHL) and seven other databases as well as two trial registers. We searched for records published in 1990 or later, as this was the year aripiprazole became available.Selection criteria: Randomised controlled trials (RCTs) of aripiprazole (administered orally and at any dosage) versus placebo for treatment of individuals with a diagnosis of ASD.

**Data collection and analysis:** 
Two review authors independently collected, evaluated and analysed data. We performed meta-analysis for primary and secondary outcomes, when possible. We used the GRADE (Grades of Recommendation, Assessment, Development and Evaluation) approach to rate the overall quality of the evidence.

**Main results:** 
We included three trials in this review. Two were included in the previous published review, and the results of one, placebo-controlled discontinuation study were added to this review. Although we searched for studies across age groups, we found only studies conducted in children and youth. Included trials had low risk of bias across most domains. High risk of bias was seen in only one trial with incomplete outcome data. We judged the overall quality of the evidence for most outcomes to be moderate.Two RCTs with similar methods evaluated use of aripiprazole for a duration of eight weeks in 316 children/adolescents with ASD. Meta-analysis of study results revealed a mean improvement of -6.17 points on the Aberrant Behavior Checklist (ABC) - Irritability subscale (95% confidence intervals (CIs) -9.07 to -3.26, two studies, 308 children/adolescents, moderate-quality evidence), -7.93 points on the ABC - Hyperactivity subscale (95% CI -10.98 to -4.88, two studies, 308 children/adolescents, moderate-quality evidence) and -2.66 points on the ABC - Stereotypy subscale (95% CI -3.55 to -1.77, two studies, 308 children/adolescents, moderate-quality evidence) in children/adolescents taking aripiprazole relative to children/adolescents taking placebo. In terms of side effects, children/adolescents taking aripiprazole had a greater increase in weight, with a mean increase of 1.13 kg relative to placebo (95% CI 0.71 to 1.54, two studies, 308 children/adolescents, moderate-quality evidence), and had a higher risk ratio (RR) for sedation (RR 4.28, 95% CI 1.58 to 11.60, two studies, 313 children/adolescents, moderate-quality evidence) and tremor (RR 10.26, 95% CI 1.37 to 76.63, two studies, 313 children/adolescents, moderate-quality evidence). A randomised, placebo-controlled discontinuation study found that 35% of children/adolescents randomised to continue intervention with aripiprazole relapsed with respect to their symptoms of irritability, compared with 52% of children/adolescents randomised to placebo, for a hazard ratio of 0.57 (95% CI 0.28 to 1.12, 85 children/adolescents, low-quality evidence).All three included trials were supported by Bristol-Myers Squibb (Princeton, NJ) and Otsuka Pharmaceutical Company, Ltd. (Tokyo, Japan), with editorial support provided by Ogilvy Healthworld Medical Education and Bristol-Myers Squibb.

**Authors&#039; conclusions:** 
Evidence from two RCTs suggests that aripiprazole can be effective as a short-term medication intervention for some behavioural aspects of ASD in children/ad l scents. After a short-term medication intervention with aripiprazole, children/adolescents showed less irritability and hyperactivity and fewer stereotypies (repetitive, purposeless actions). However, notable side effects, such as weight gain, sedation, drooling and tremor, must be considered. One long-term, placebo discontinuation study found that relapse rates did not differ between children/adolescents randomised to continue aripiprazole versus children/adolescents randomised to receive placebo, suggesting that re-evaluation of aripiprazole use after a period of stabilisation in irritability symptoms is warranted. Studies included in this review used criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) (APA 2000) for ASD diagnosis; however, the diagnostic criteria for ASD changed significantly with release of the fifth edition of the DSM (DSM-5) in 2013 (APA 2013).
AN  - CD009043
AU  - Hirsch,
AU  - L.
AU  - E.
AU  - Pringsheim,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009043.pub3
KW  - Antipsychotic Agents [therapeutic use]
KW  - Aripiprazole [therapeutic use]
KW  - Child Development Disorders, Pervasive [drug therapy]
KW  - Hyperkinesis [drug therapy]
KW  - Irritable Mood [drug effects]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Behav
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Aripiprazole for autism spectrum disorders (ASD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009043.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009043.pub3/asset/CD009043.pdf?v=1&amp;t=iw7is16w&amp;s=b9dbbee34e3b96e3079fb27e0e3180755a15f1c1
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Findings from systematic reviews and meta-analyses about the effectiveness of school-based programmes to prevent or reduce substance abuse are inconclusive. We hypothesise that in order to be effective, programmes have to be aligned with the developmental stages of the intended target group (childhood, early, middle, or late adolescence). The present study provides an overview of universal and targeted programmes, while distinguishing four age groups and examining which intervention characteristics are the effective components for the respective groups. 

**METHODS: **
Databases were searched for controlled studies of school-based programmes, evaluating their effectiveness on either smoking, alcohol or drug use. Multivariate meta-regression analysis was used to analyse the associations between effects and programme characteristics. 

**RESULTS: **
Our meta-analysis evaluates 288 programmes with a total of 436,180 participants. The findings support our hypothesis that specific aspects of the school-based programmes are effective in some developmental stages, but not for other age groups. The differences in effectiveness are systematically related to psychological and cognitive needs and capacities. 

**DISCUSSION: **
Our findings highlight the importance of considering a developmental perspective when designing and offering school-based prevention programmes. The various developmental stages offer different possibilities and opportunities for the reduction and prevention of substance use. 

Copyright &copy; 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.
AD  - Onrust, Simone A. Trimbos Institute, Utrecht, The Netherlands. Electronic address: sonrust@trimbos.nl. Otten, Roy. Department of Research and Development, Pluryn, Nijmegen, The Netherlands. Lammers, Jeroen. Trimbos Institute, Utrecht, The Netherlands. Smit, Filip. Trimbos Institute, Utrecht, The Netherlands; Department of Clinical Psychology, EMGO, VU University, Amsterdam, The Netherlands; Department of Epidemiology and Biostatistics, VU University Medical Centre, Amsterdam, The Netherlands.
AN  - 26722708
AU  - Onrust,
AU  - S.
AU  - A.
AU  - Otten,
AU  - R.
AU  - Lammers,
AU  - J.
AU  - Smit,
AU  - F.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10566-015-9315-0
DP  - Ovid Technologies
J2  - Clin Psychol Rev
KW  - Adolescent
KW  - Age Factors
KW  - *Alcohol Drinking/pc [Prevention &amp; Control]
KW  - Female
KW  - Humans
KW  - Male
KW  - *School Health Services
KW  - *Schools
KW  - *Smoking/pc [Prevention &amp; Control]
KW  - *Substance-Related Disorders/pc [Prevention &amp; Control]
L1  - internal-pdf://0160471449/Onrust-2016-School-based programmes to reduce.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Onrust, Simone A Otten, Roy Lammers, Jeroen Smit, Filip S0272-7358(15)00152-X
PY  - 2016
SP  - 45-59
T2  - Clinical Psychology Review
TI  - School-based programmes to reduce and prevent substance use in different age groups: What works for whom? Systematic review and meta-regression analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26722708http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26722708&amp;id=doi:10.1016%2Fj.cpr.2015.11.002&amp;issn=0272-7358&amp;isbn=&amp;volume=44&amp;issue=&amp;spage=45&amp;pages=45-59&amp;date=2016&amp;title=Clinical+Psychology+Review&amp;atitle=School-based+programmes+to+reduce+and+prevent+substance+use+in+different+age+groups%3A+What+works+for+whom%3F+Systematic+review+and+meta-regression+analysis.&amp;aulast=Onrust&amp;pid=%3Cauthor%3EOnrust+SA%3C%2Fauthor%3E%3CAN%3E26722708%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S027273581500152X/1-s2.0-S027273581500152X-main.pdf?_tid=b8c8474a-04cd-11e7-95c2-00000aab0f27&amp;acdnat=1489066907_377e3a2eaed56b1e90b7bcb24376f5ad
VL  - 44
ER  -
TY  - JOUR
AB  - We conducted a comprehensive search and the overview included 22 systematic reviews (SRs) for treating tic disorders (TDs). Three SRs indicated typical antipsychotics (i.e., haloperidol, pimozide) were efficacious in the reduction of tic severity compared with placebo but with poor tolerability. 

Six SRs assessed the efficacy of atypical antipsychotics and indicated that atypical antipsychotics (i.e., risperidone, aripiprazole) could significantly improved tic symptoms compared with placebo or typical antipsychotics with less AEs. Four SRs indicated alpha adrenergic agonists (i.e., clonidine, guanfacine) could improve tic symptoms. 

Two SRs assessed the efficacy of antiepileptic drugs and indicated topiramate was a promising therapy. Six SRs evaluated the efficacy of behavior therapy and showed habit reversal therapy (HRT) and exposure and response prevention (ERP) were effective. 

One SR evaluated the efficacy deep brain stimulation (DBS) and indicated DBS is a promising treatment option for severe cases of TS. In conclusion, RCTs directly comparing different pharmacological treatment options are scarce. 

In practice, typical and atypical antipsychotics are often considered firstly while other pharmacological medications are suggested as alternatives in the case of treatment failure or contradictory outcomes. Behavioral therapies can be used either alone or in combination with medication. 

Copyright &copy; 2016. Published by Elsevier Ltd.
AD  - Yang, Chunsong. Department of Pharmacy, Evidence-Based Pharmacy Center, West China Second Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, China. Hao, Zilong. Department of Neurology, West China Hospital, Sichuan University, Chengdu, China. Zhu, Cairong. West China School of Public Health, Sichuan University, China. Guo, Qin. Department of Pediatrics, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. Mu, Dezhi. Department of Pediatrics, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. Zhang, Lingli. Department of Pharmacy, Evidence-Based Pharmacy Center, West China Second Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, China. Electronic address: zhlingli@sina.com.
AN  - 26751711
AU  - Yang,
AU  - C.
AU  - Hao,
AU  - Z.
AU  - Zhu,
AU  - C.
AU  - Guo,
AU  - Q.
AU  - Mu,
AU  - D.
AU  - Zhang,
AU  - L.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.neubiorev.2015.12.013
DP  - Ovid Technologies
J2  - Neurosci Biobehav Rev
KW  - Adolescent
KW  - Adrenergic alpha-2 Receptor Agonists/ae [Adverse Effects]
KW  - *Adrenergic alpha-2 Receptor Agonists/tu [Therapeutic Use]
KW  - Adult
KW  - Aged
KW  - Antipsychotic Agents/ae [Adverse Effects]
KW  - *Antipsychotic Agents/tu [Therapeutic Use]
KW  - Child
KW  - Child, Preschool
KW  - *Cognitive Therapy
KW  - *Deep Brain Stimulation
KW  - Female
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Randomized Controlled Trials as Topic
KW  - Tic Disorders/dt [Drug Therapy]
KW  - *Tic Disorders/th [Therapy]
KW  - Treatment Outcome
KW  - Young Adult
KW  - 0 (Adrenergic alpha-2 Receptor Agonists)
KW  - 0 (Antipsychotic Agents)
L1  - internal-pdf://0809038970/Yang-2016-Interventions for tic disorders_ An.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Yang, Chunsong Hao, Zilong Zhu, Cairong Guo, Qin Mu, Dezhi Zhang, Lingli S0149-7634(15)30208-6
PY  - 2016
SP  - 239-55
T2  - Neuroscience &amp; Biobehavioral Reviews
TI  - Interventions for tic disorders: An overview of systematic reviews and meta analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26751711http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26751711&amp;id=doi:10.1016%2Fj.neubiorev.2015.12.013&amp;issn=0149-7634&amp;isbn=&amp;volume=63&amp;issue=&amp;spage=239&amp;pages=239-55&amp;date=2016&amp;title=Neuroscience+%26+Biobehavioral+Reviews&amp;atitle=Interventions+for+tic+disorders%3A+An+overview+of+systematic+reviews+and+meta+analyses.&amp;aulast=Yang&amp;pid=%3Cauthor%3EYang+C%3C%2Fauthor%3E%3CAN%3E26751711%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0149763415302086/1-s2.0-S0149763415302086-main.pdf?_tid=7377b752-04d2-11e7-92a3-00000aacb362&amp;acdnat=1489068938_19ac6b46aea24644895b1c451af58a59
VL  - 63
ER  -
TY  - JOUR
AB  - Foster care is often preferred to other placement options for children in the child welfare system. 

However, it is not clear how the developmental outcomes of foster children relate to children in other living arrangements. 

In this study, a series of meta-analyses are performed to compare the cognitive, adaptive, and behavioral functioning of children placed in foster care (n = 2,305) with children at risk who remained with their biological parents (n = 4,335) and children from the general population (n = 4,971). 

A systematic literature search in PsycINFO, Medline, ERIC, and ProQuest identified 31 studies suitable for inclusion (N = 11,611). 

Results showed that foster children had generally lower levels of functioning than children from the general population. No clear differences were found between foster children and children at risk who remained at home, but both groups experienced developmental problems. 

Improving the quality of foster care and future research to identify which children are best served by either foster care or in-home services are recommended.
AN  - 27481915
AU  - Goemans,
AU  - A.
AU  - van
AU  - Geel,
AU  - M.
AU  - van
AU  - Beem,
AU  - M.
AU  - Vedder,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1077559516657637
L1  - internal-pdf://2671617259/Goemans-2016-Developmental Outcomes of Foster.pdf
PY  - 2016
SP  - 198-217
T2  - Child Maltreatment
TI  - Developmental Outcomes of Foster Children: A Meta-Analytic Comparison With Children From the General Population and Children at Risk Who Remained at Home
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=27481915
UR  - http://journals.sagepub.com/doi/abs/10.1177/1077559516657637?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
UR  - http://journals.sagepub.com/doi/pdf/10.1177/1077559516657637
VL  - 21
ER  -
TY  - JOUR
AB  - Children with attention-deficit/hyperactivity disorder (ADHD) often exhibit problem behavior in class, which teachers often struggle to manage due to a lack of knowledge and skills to use classroom management strategies. 

The aim of this meta-analytic review was to determine the effectiveness of several types of classroom interventions (antecedent-based, consequence- based, self-regulation, combined) that can be applied by teachers in order to decrease off-task and disruptive classroom behavior in children with symptoms of ADHD. 

A second aim was to identify potential moderators (classroom setting, type of measure, students&#039; age, gender, intelligence, and medication use). Finally, it was qualitatively explored whether the identified classroom interventions also directly or indirectly affected behavioral and academic outcomes of classmates. Separate meta-analyses were performed on standardized mean differences (SMDs) for 24 within-subjects design (WSD) and 76 single-subject design (SSD) studies. 

Results showed that classroom interventions reduce off-task and disruptive classroom behavior in children with symptoms of ADHD (WSDs: M&lt;inf&gt;SMD&lt;/inf&gt; = 0.92; SSDs: M&lt;inf&gt;SMD&lt;/inf&gt; = 3.08), with largest effects for consequence-based (WSDs: M&lt;inf&gt;SMD&lt;/inf&gt; = 1.82) and self-regulation interventions (SSDs: M&lt;inf&gt;SMD&lt;/inf&gt; = 3.61). Larger effects were obtained in general education classrooms than in other classroom settings. 

No reliable conclusions could be formulated about moderating effects of type of measure and students&#039; age, gender, intelligence, and medication use, mainly because of power problems. Finally, classroom interventions appeared to also benefit classmates&#039; behavioral and academic outcomes. 

Copyright &copy; 2016 Gaastra et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
AN  - 608829344
AU  - Gaastra,
AU  - G.
AU  - F.
AU  - Groen,
AU  - Y.
AU  - Tucha,
AU  - L.
AU  - Tucha,
AU  - O.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0148841
L1  - internal-pdf://0632982464/Gaastra-2016-The effects of classroom interven.pdf
PY  - 2016
TI  - The effects of classroom interventions on off-task and disruptive classroom behavior in children with symptoms of attention-deficit/hyperactivity disorder: A meta-analytic review
UR  - http://www.plosone.org/article/fetchObject.action?uri=info:doi/10.1371/journal.pone.0148841&amp;representation=PDF
VL  - 11 (2) (no pagination)
ER  -
TY  - JOUR
AB  - **PURPOSE: **
Health education in school classrooms can be effective in promoting sexual health and preventing violence and substance use but effects are patchy and often short term. Classroom education is also challenging because of schools&#039; increasing focus on academic-performance metrics. Other school-based approaches are possible, such as healthy school policies, improving how schools respond to bullying, and parent outreach, which go beyond health education to address broader health determinants. Existing systematic reviews include such interventions but often alongside traditional health education. There is scope for a systematic review of reviews to assess and synthesize evidence across existing reviews to develop an overview of the potential of alternative school-based approaches. 

**METHODS: **
We searched 12 databases to identify reviews published after 1980. Data were reviewed by two researchers. Quality was assessed using a modified Assessing the Methodological Quality of Systematic Reviews checklist and results were synthesized narratively. 

**RESULTS: **
We screened 7,544 unique references and included 22 reviews. Our syntheses suggest that multicomponent school-based interventions, for example, including school policy changes, parent involvement, and work with local communities, are effective for promoting sexual health and preventing bullying and smoking. There is less evidence that such intervention can reduce alcohol and drug use. Economic incentives to keep girls in school can reduce teenage pregnancies. School clinics can promote smoking cessation. There is little evidence that, on their own, sexual-health clinics, antismoking policies, and various approaches targeting at-risk students are effective. 

**CONCLUSIONS: **
There is good evidence that various whole-school health interventions are effective in preventing teenage pregnancy, smoking, and bullying. 

Copyright &copy; 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.
AD  - Shackleton, Nichola. Centre of Methods and Policy Application in the Social Sciences, University of Auckland, Auckland, New Zealand. Jamal, Farah. Department of Social Science, University College London Institute of Education, London, United Kingdom. Viner, Russell M. University College London Institute of Child Health, London, United Kingdom. Dickson, Kelly. Department of Social Science, University College London Institute of Education, London, United Kingdom. Patton, George. School Of Paediatrics, Royal Children&#039;s Hospital, University of Melbourne, Parkville, Victoria, Australia. Bonell, Christopher. Department of Social Science, University College London Institute of Education, London, United Kingdom. Electronic address: c.bonell@ioe.ac.uk.
AN  - 27013271
AU  - Shackleton,
AU  - N.
AU  - Jamal,
AU  - F.
AU  - Viner,
AU  - R.
AU  - M.
AU  - Dickson,
AU  - K.
AU  - Patton,
AU  - G.
AU  - Bonell,
AU  - C.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jadohealth.2015.12.017
DP  - Ovid Technologies
J2  - J Adolesc Health
KW  - Adolescent
KW  - *Adolescent Health
KW  - Bullying/pc [Prevention &amp; Control]
KW  - Female
KW  - Health Education/mt [Methods]
KW  - *Health Education
KW  - *Health Promotion
KW  - Humans
KW  - Male
KW  - Program Evaluation
KW  - Reproductive Health/ed [Education]
KW  - Review Literature as Topic
KW  - *School Health Services
KW  - Sex Education
KW  - Smoking/pc [Prevention &amp; Control]
L1  - internal-pdf://2539436577/Shackleton-2016-School-Based Interventions Goi.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Shackleton, Nichola Jamal, Farah Viner, Russell M Dickson, Kelly Patton, George Bonell, Christopher S1054-139X(15)00736-3
PY  - 2016
SP  - 382-96
T2  - Journal of Adolescent Health
TI  - School-Based Interventions Going Beyond Health Education to Promote Adolescent Health: Systematic Review of Reviews
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=27013271http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27013271&amp;id=doi:10.1016%2Fj.jadohealth.2015.12.017&amp;issn=1054-139X&amp;isbn=&amp;volume=58&amp;issue=4&amp;spage=382&amp;pages=382-96&amp;date=2016&amp;title=Journal+of+Adolescent+Health&amp;atitle=School-Based+Interventions+Going+Beyond+Health+Education+to+Promote+Adolescent+Health%3A+Systematic+Review+of+Reviews.&amp;aulast=Shackleton&amp;pid=%3Cauthor%3EShackleton+N%3C%2Fauthor%3E%3CAN%3E27013271%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S1054139X15007363/1-s2.0-S1054139X15007363-main.pdf?_tid=a3d212ec-04cf-11e7-bef2-00000aacb35e&amp;acdnat=1489067731_89c539a0b6523d1b5a4355ae6563c82e
VL  - 58
ER  -
TY  - JOUR
AB  - This meta-analysis aimed at determining the efficacy of psychological and psychopharmacological interventions for children and adolescents suffering from symptoms of posttraumatic stress disorder (PTSD). 

A search using the Medline, PsycINFO, and PILOTS databases was conducted to identify randomized controlled trials (RCTs) for pediatric PTSD. The search resulted in 41 RCTs, of which 39 were psychological interventions and two psychopharmacological interventions. 

Results showed that psychological interventions are effective in treating PTSD, with aggregated effect sizes of Hedge&#039;s g=0.83 when compared to waitlist and g=0.41 when compared to active control conditions at posttreatment. Trauma-focused cognitive behavior therapy was the most researched form of intervention and resulted in medium to large effect sizes when compared to waitlist (g=1.44) and active control conditions (g=0.66). 

Experimental conditions were also more effective than control conditions at follow-up. Interventions were further effective in reducing comorbid depression symptoms, yet the obtained effect sizes were small to medium only. 

The findings indicate that psychological interventions can effectively reduce PTSD symptoms in children and adolescents. There is very little evidence to support use of psychopharmacological interventions for pediatric PTSD. 

Copyright &copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Morina, Nexhmedin. Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands; Amsterdam Brain and Cognition Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: n.morina@uva.nl. Koerssen, Rachel. Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands. Pollet, Thomas V. Department of Experimental and Applied Psychology, Vrije Universiteit Amsterdam, The Netherlands.
AN  - 27340855
AU  - Morina,
AU  - N.
AU  - Koerssen,
AU  - R.
AU  - Pollet,
AU  - T.
AU  - V.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2016.05.006
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://4292903074/Morina-2016-Interventions for children and ado.pdf
LA  - English
M3  - Review
N1  - Morina, Nexhmedin Koerssen, Rachel Pollet, Thomas V S0272-7358(16)30069-1
PY  - 2016
SP  - 41-54
T2  - Clinical Psychology Review
TI  - Interventions for children and adolescents with posttraumatic stress disorder: A meta-analysis of comparative outcome studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27340855http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27340855&amp;id=doi:10.1016%2Fj.cpr.2016.05.006&amp;issn=0272-7358&amp;isbn=&amp;volume=47&amp;issue=&amp;spage=41&amp;pages=41-54&amp;date=2016&amp;title=Clinical+Psychology+Review&amp;atitle=Interventions+for+children+and+adolescents+with+posttraumatic+stress+disorder%3A+A+meta-analysis+of+comparative+outcome+studies.&amp;aulast=Morina&amp;pid=%3Cauthor%3EMorina+N%3C%2Fauthor%3E%3CAN%3E27340855%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0272735816300691/1-s2.0-S0272735816300691-main.pdf?_tid=0f43f3cc-04cd-11e7-b089-00000aab0f01&amp;acdnat=1489066622_d9149360e1b9c16f206b78b6a0277054
VL  - 47
ER  -
TY  - JOUR
AB  - New generation antidepressant therapies, including serotonin-norepinephrine reuptake inhibitor (SNRIs), were introduced in the late 1980s; however, few comprehensive studies have compared the benefits and risks of various contemporary treatments for major depressive disorder (MDD) in young patients. 

A comprehensive literature search of PubMed, Cochrane, Embase, Web of Science, and PsycINFO databases was conducted from 1970 to January 2015. Only clinical trials that randomly assigned one SNRI or placebo to patients aged 7 to 18 years who met the diagnostic criteria for major depressive disorder were included. Treatment success, dropout rate, and suicidal ideation/attempt outcomes were measured. 

Primary efficacy was determined by pooling the risk ratios (RRs) of treatment response and remission. Acceptability was determined by pooling the RRs of dropouts for all reasons and for adverse effects as well as suicide-risk outcomes. Five trials with a total of 973 patients were included. SNRIs were not significantly more effective than placebo for treatment response but were for remission. 

The comparison of patients taking SNRIs that dropped out for all reasons and those taking placebo did not reach statistical significance. Significantly more patients taking SNRIs dropped out for adverse effects than those taking placebo. No significant difference was found in suicide-related risk outcomes. 

SNRI therapy does not display a superior efficacy and is not better tolerated compared to placebo in these young patients. However, duloxetine has a potential beneficial effect for depression in young populations, showing a need for further research.
AD  - Xu, Y. Department of Neurology, Yongchuan Hospital, Chongqing Medical University, Chongqing, China. Xu, Y. Chongqing Key Laboratory of Neurobiology, Chongqing, China. Xu, Y. Institute of Neuroscience, Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Bai, S J. Department of Neurology, Yongchuan Hospital, Chongqing Medical University, Chongqing, China. Bai, S J. Chongqing Key Laboratory of Neurobiology, Chongqing, China. Bai, S J. Institute of Neuroscience, Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Lan, X H. Chongqing Key Laboratory of Neurobiology, Chongqing, China. Lan, X H. Institute of Neuroscience, Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Qin, B. Department of Neurology, Yongchuan Hospital, Chongqing Medical University, Chongqing, China. Qin, B. Chongqing Key Laboratory of Neurobiology, Chongqing, China. Qin, B. Institute of Neuroscience, Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Huang, T. Department of Neurology, Yongchuan Hospital, Chongqing Medical University, Chongqing, China. Huang, T. Chongqing Key Laboratory of Neurobiology, Chongqing, China. Huang, T. Institute of Neuroscience, Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Xie, P. Department of Neurology, Yongchuan Hospital, Chongqing Medical University, Chongqing, China. Xie, P. Chongqing Key Laboratory of Neurobiology, Chongqing, China. Xie, P. Institute of Neuroscience, Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China.
AN  - 27240293
AU  - Xu,
AU  - Y.
AU  - Bai,
AU  - S.
AU  - J.
AU  - Lan,
AU  - X.
AU  - H.
AU  - Qin,
AU  - B.
AU  - Huang,
AU  - T.
AU  - Xie,
AU  - P.
DA  - May 24
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1590/1414-431X20164806
DP  - Ovid Technologies
J2  - Braz J Med Biol Res
KW  - Adolescent
KW  - *Antidepressive Agents/tu [Therapeutic Use]
KW  - Child
KW  - Cyclopropanes/tu [Therapeutic Use]
KW  - *Depressive Disorder, Major/dt [Drug Therapy]
KW  - Desvenlafaxine Succinate/tu [Therapeutic Use]
KW  - Duloxetine Hydrochloride/tu [Therapeutic Use]
KW  - Female
KW  - Humans
KW  - Male
KW  - Placebos/tu [Therapeutic Use]
KW  - *Randomized Controlled Trials as Topic
KW  - *Serotonin and Noradrenaline Reuptake Inhibitors/tu [Therapeutic Use]
KW  - Treatment Outcome
KW  - Venlafaxine Hydrochloride/tu [Therapeutic Use]
KW  - 0 (Antidepressive Agents)
KW  - 0 (Cyclopropanes)
KW  - 0 (Placebos)
KW  - 0 (Serotonin and Noradrenaline Reuptake Inhibitors)
KW  - 7D7RX5A8MO (Venlafaxine Hydrochloride)
KW  - 9044SC542W (Duloxetine Hydrochloride)
KW  - G56VK1HF36 (milnacipran)
KW  - ZB22ENF0XR (Desvenlafaxine Succinate)
L1  - internal-pdf://1911353631/1414-431X-bjmbr-1414-431X20164806.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Xu, Y Bai, S J Lan, X H Qin, B Huang, T Xie, P Using Smart Source Parsing May S0100-879X2016000600704
PY  - 2016
SP  - 24
T2  - Brazilian Journal of Medical and Biological Research
TI  - Randomized controlled trials of serotonin-norepinephrine reuptake inhibitor in treating major depressive disorder in children and adolescents: a meta-analysis of efficacy and acceptability
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=27240293http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27240293&amp;id=doi:10.1590%2F1414-431X20164806&amp;issn=0100-879X&amp;isbn=&amp;volume=49&amp;issue=6&amp;spage=&amp;pages=&amp;date=2016&amp;title=Brazilian+Journal+of+Medical+%26+Biological+Research&amp;atitle=Randomized+controlled+trials+of+serotonin-norepinephrine+reuptake+inhibitor+in+treating+major+depressive+disorder+in+children+and+adolescents%3A+a+meta-analysis+of+efficacy+and+acceptability.&amp;aulast=Xu&amp;pid=%3Cauthor%3EXu+Y%3C%2Fauthor%3E%3CAN%3E27240293%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 49
ER  -
TY  - JOUR
AB  - To obtain the risk estimates of autism spectrum disorder (ASD) in the offspring exposed to serotonin reuptake inhibitors (SSRI) in utero, we performed systematic review and meta-analysis of relevant studies. 

Five case-control and three cohort studies were eligible for the analysis. The SSRI group had significantly higher risk of ASD than the SSRI non-exposed group (pooled OR 1.45, 95% CI 1.15-1.82). In the subgroup analyses, however, the risk of ASD was similar between the SSRI group and other antidepressants group (pooled OR 1.14, 95% CI 0.67-1.96). 

Furthermore, when the analysis was confined to those born to the women with psychiatric disorders, the SSRI group did not show an increased ASD risk (pooled OR 0.96, 95% CI 0.57-1.63) compared to non-exposed groups. 

In conclusion, SSRI use in pregnancy is associated with an increased risk of ASD in the offspring, but maternal psychiatric condition is a major confounding factor. 

Copyright &copy; 2016 Elsevier Inc.
AD  - (Kobayashi, Matsuyama, Takeuchi, Ito) Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Canada (Kobayashi) Division of Research Planning, Department of Development Strategy, Center for Clinical Research and Development, National Center for Child Health and Development, Japan (Matsuyama) Department of Emergency Medicine, Kyoto Prefectural University of Medicine, Japan (Ito) Motherisk program, The Hospital for Sick Children, Canada S. Ito, Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Canada. E-mail: shinya.ito@sickkids.ca
AN  - 611514311
AU  - Kobayashi,
AU  - T.
AU  - Matsuyama,
AU  - T.
AU  - Takeuchi,
AU  - M.
AU  - Ito,
AU  - S.
DA  - 01 Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.reprotox.2016.07.016
DP  - Ovid Technologies
KW  - Autism spectrum disorder
KW  - Child
KW  - Meta-analysis
KW  - Prenatal exposure delayed effect
KW  - Serotonin reuptake inhibitors
KW  - anxiety
KW  - article
KW  - autism
KW  - bipolar disorder
KW  - case control study
KW  - cohort analysis
KW  - depression
KW  - disease association
KW  - drug exposure
KW  - eating disorder
KW  - human
KW  - intrauterine growth retardation
KW  - mania
KW  - meta analysis
KW  - mood disorder
KW  - neurosis
KW  - personality disorder
KW  - posttraumatic stress disorder
KW  - prenatal exposure
KW  - psychosis
KW  - psychosomatic disorder
KW  - randomized controlled trial (topic)
KW  - risk factor
KW  - schizophrenia
KW  - substance abuse
KW  - systematic review
KW  - non selective monoamine reuptake inhibitor
KW  - noradrenalin uptake inhibitor
KW  - serotonin uptake inhibitor
KW  - tricyclic antidepressant agent
KW  - unclassified drug
KW  - controlled study
KW  - female
KW  - population based case control study
KW  - pregnancy
KW  - progeny
L1  - internal-pdf://3836553281/Kobayashi-2016-Autism spectrum disorder and pr.pdf
LA  - English
PY  - 2016
SP  - 170-178
T2  - Reproductive Toxicology
TI  - Autism spectrum disorder and prenatal exposure to selective serotonin reuptake inhibitors: A systematic review and meta-analysis
UR  - http://www.elsevier.com/inca/publications/store/5/2/5/4/8/9/index.htthttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=611514311http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.reprotox.2016.07.016&amp;issn=0890-6238&amp;isbn=&amp;volume=65&amp;issue=&amp;spage=170&amp;pages=170-178&amp;date=2016&amp;title=Reproductive+Toxicology&amp;atitle=Autism+spectrum+disorder+and+prenatal+exposure+to+selective+serotonin+reuptake+inhibitors%3A+A+systematic+review+and+meta-analysis&amp;aulast=Kobayashi&amp;pid=%3Cauthor%3EKobayashi+T.%3C%2Fauthor%3E%3CAN%3E611514311%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0890623816303033/1-s2.0-S0890623816303033-main.pdf?_tid=02c595ea-04ca-11e7-bb36-00000aab0f6c&amp;acdnat=1489065313_69d51631f03e865146bfa42980f7a0d8
VL  - 65
ER  -
TY  - JOUR
AB  - The present study is a quantitative synthesis of the available literature to investigate the efficacy of psychotherapy for children&#039;s mental health outcomes. In particular, this study focuses on potential moderating variables-study design, treatment, client, and therapist characteristics-that may influence therapeutic outcomes for youth but have not been thoroughly accounted for in prior meta-analytic studies. 

An electronic search of relevant databases resulted in 190 unpublished and published studies that met criteria for inclusion in the analysis. Effect sizes differed by study design. Pre-post-test designs resulted in absolute magnitudes of treatment effects ranging from -0.02 to -0.76 while treatment versus control group comparison designs resulted in absolute magnitudes of treatment effects ranging from -0.14 -2.39 . 

Changes in youth outcomes larger than 20% were found, irrespective of study design, for outcomes focused on psychosomatization (29% reduction), school attendance (25% increase), and stress (48% reduction). The magnitude of changes after psychotherapy ranged from 6% (externalizing problems) to 48% (stress). Several moderator variables significantly influenced psychotherapy treatment effect sizes, including frequency and length of treatment as well as treatment format. 

However, results did not support the superiority of a single type of intervention for most outcomes. Implications for therapy with school-aged youth and future research are discussed. 

Copyright &copy; 2016 Society for the Study of School Psychology. 
Published by Elsevier Ltd. All rights reserved.
AD  - Fedewa, Alicia L. Department of Educational, School, and Counseling Psychology, University of Kentucky, United States. Electronic address: alicia.fedewa@uky.edu. Ahn, Soyeon. Department of Educational and Psychological Studies, University of Miami, United States. Reese, Robert J. Department of Educational, School, and Counseling Psychology, University of Kentucky, United States. Suarez, Marietta M. Department of Educational and Psychological Studies, University of Miami, United States. Macquoid, Ahjane. Department of Educational and Psychological Studies, University of Miami, United States. Davis, Matthew C. Department of Educational, School, and Counseling Psychology, University of Kentucky, United States. Prout, H Thompson. Department of Educational, School, and Counseling Psychology, University of Kentucky, United States.
AN  - 27268570
AU  - Fedewa,
AU  - A.
AU  - L.
AU  - Ahn,
AU  - S.
AU  - Reese,
AU  - R.
AU  - J.
AU  - Suarez,
AU  - M.
AU  - M.
AU  - Macquoid,
AU  - A.
AU  - Davis,
AU  - M.
AU  - C.
AU  - Prout,
AU  - H.
AU  - T.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jsp.2016.03.001
DP  - Ovid Technologies
J2  - J Sch Psychol
L1  - internal-pdf://1842536617/Fedewa-2016-Does psychotherapy work with schoo.pdf
LA  - English
N1  - Fedewa, Alicia L Ahn, Soyeon Reese, Robert J Suarez, Marietta M Macquoid, Ahjane Davis, Matthew C Prout, H Thompson S0022-4405(16)30003-6
PY  - 2016
SP  - 59-87
T2  - Journal of School Psychology
TI  - Does psychotherapy work with school-aged youth? A meta-analytic examination of moderator variables that influence therapeutic outcomes
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27268570http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27268570&amp;id=doi:10.1016%2Fj.jsp.2016.03.001&amp;issn=0022-4405&amp;isbn=&amp;volume=56&amp;issue=&amp;spage=59&amp;pages=59-87&amp;date=2016&amp;title=Journal+of+School+Psychology&amp;atitle=Does+psychotherapy+work+with+school-aged+youth%3F+A+meta-analytic+examination+of+moderator+variables+that+influence+therapeutic+outcomes.&amp;aulast=Fedewa&amp;pid=%3Cauthor%3EFedewa+AL%3C%2Fauthor%3E%3CAN%3E27268570%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0022440516300036/1-s2.0-S0022440516300036-main.pdf?_tid=6a23661c-04c6-11e7-b41d-00000aacb361&amp;acdnat=1489063768_9c30241a71373ca865e464bd7fa96067
VL  - 56
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
Early-onset schizophrenia (EOS) is a serious debilitating disorder with considerable morbidity and a reduced life expectancy; therefore, early diagnosis and effective treatments are particularly important. Negative symptoms are more prominent in adolescents and children (compared with adults), and are key predictors of worse functional and clinical outcomes in EOS. Therefore, this study aimed to explore the relative efficacy of antipsychotics used in the treatment of EOS, with a focus on studies reporting effectiveness using the Positive and Negative Syndrome scale (PANSS), a scale that includes an overall symptom measure, in addition to separate subscales for positive and, importantly, negative symptoms. 

**METHODS: **
A systematic literature review was conducted using the MEDLINE and Cochrane Central Register of Controlled Trials databases to identify trials conducted in children and adolescents with schizophrenia, and symptom control was reported using the PANSS. A Bayesian random-effects network meta-analysis was performed, synthesising data for a number of outcomes, including mean change from baseline in PANSS scores, treatment discontinuation and weight gain. 

**RESULTS: **
Eleven studies were included in the evidence synthesis, comprising 1714 patients across eight active interventions (aripiprazole, haloperidol, molindone, olanzapine, paliperidone, quetiapine, risperidone and ziprasidone) and placebo. All treatments showed a greater reduction in total PANSS scores vs placebo; however, only three interventions (molindone, olanzapine and risperidone) were associated with a statistically significant reduction in total PANSS scores at 6 weeks vs placebo. Haloperidol had the greatest reduction vs placebo; however, this result was not statistically significant [mean difference, -15.6, 95% credible interval (-35.4, 4.1)]. Haloperidol, olanzapine and risperidone showed a statistically significant reduction in positive PANSS scores vs placebo; however, whilst all interventions showed a trend of reduction in negative PANSS scores vs placebo, no comparisons were statistically significant. 

**CONCLUSIONS: **
Many of the treatments are efficacious in controlling symptoms, and all showed a trend of superiority vs placebo for total, positive and negative PANSS scores, although only olanzapine and risperidone yielded statistically significant results vs placebo for both total and positive PANSS scores. Varying results for discontinuation and weight gain demonstrate a need to balance efficacy with side-effect profiles.
AD  - Harvey, Rebecca C. BresMed Health Solutions, North Church Business House, 84 Queen Street, Sheffield, S1 2DW, UK. bharvey@bresmed.co.uk. James, Anthony C. Highfield Unit Oxford, Warneford Hospital, Oxford, UK. Shields, Gemma E. BresMed Health Solutions, North Church Business House, 84 Queen Street, Sheffield, S1 2DW, UK.
AN  - 26801655
AU  - Harvey,
AU  - R.
AU  - C.
AU  - James,
AU  - A.
AU  - C.
AU  - Shields,
AU  - G.
AU  - E.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s40263-015-0308-1
DP  - Ovid Technologies
J2  - CNS Drugs
KW  - Adolescent
KW  - *Antipsychotic Agents/ae [Adverse Effects]
KW  - *Antipsychotic Agents/tu [Therapeutic Use]
KW  - Child
KW  - Humans
KW  - Psychiatric Status Rating Scales
KW  - Randomized Controlled Trials as Topic
KW  - *Schizophrenia/dt [Drug Therapy]
KW  - *Schizophrenic Psychology
KW  - Treatment Outcome
KW  - 0 (Antipsychotic Agents)
L1  - internal-pdf://0700185070/Harvey-2016-A Systematic Review and Network Me.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Harvey, Rebecca C James, Anthony C Shields, Gemma E 10.1007/s40263-015-0308-1
PY  - 2016
SP  - 27-39
T2  - CNS Drugs
TI  - A Systematic Review and Network Meta-Analysis to Assess the Relative Efficacy of Antipsychotics for the Treatment of Positive and Negative Symptoms in Early-Onset Schizophrenia
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26801655http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26801655&amp;id=doi:10.1007%2Fs40263-015-0308-1&amp;issn=1172-7047&amp;isbn=&amp;volume=30&amp;issue=1&amp;spage=27&amp;pages=27-39&amp;date=2016&amp;title=CNS+Drugs&amp;atitle=A+Systematic+Review+and+Network+Meta-Analysis+to+Assess+the+Relative+Efficacy+of+Antipsychotics+for+the+Treatment+of+Positive+and+Negative+Symptoms+in+Early-Onset+Schizophrenia.&amp;aulast=Harvey&amp;pid=%3Cauthor%3EHarvey+RC%3C%2Fauthor%3E%3CAN%3E26801655%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://link.springer.com/article/10.1007%2Fs40263-015-0308-1
UR  - http://download.springer.com/static/pdf/637/art%253A10.1007%252Fs40263-015-0308-1.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs40263-015-0308-1&amp;token2=exp=1489074471~acl=%2Fstatic%2Fpdf%2F637%2Fart%25253A10.1007%25252Fs40263-015-0308-1.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs40263-015-0308-1*~hmac=c317b033c4de91be0daf15993084a4d37cc2c0c47fca4f78ae29a09ece5b6f3a
VL  - 30
ER  -
TY  - JOUR
AB  - Tourette syndrome (TS) is a neuropsychiatric disorder that affects both children and adults. We searched for randomised controlled trials (RCTs) using acupuncture to treat TS written in English or Chinese without restrictions on publication status. 

Study selection, data extraction, and assessment of study quality were conducted independently by two reviewers. Meta-analyses were performed using Review Manager (RevMan) 5.3 software from the Cochrane Collaboration. Data were combined with the fixed-effect model based on a heterogeneity test. 

Results were presented as risk ratios for dichotomous data and mean differences (MDs) for continuous data. This review included 7 RCTs with a total of 564 participants. The combined results showed that acupuncture may have better short-term effect than Western medicine for TS and that acupuncture may be an effective adjuvant therapy in improving the effect of Western medicine on TS, but the evidence is limited because of existing biases. 

Rigorous high-quality RCTs are needed to verify these findings.
AD  - Yu, Jinna. Acupuncture Department, Guang&#039;anmen Hospital, China Academy of Chinese Medical Sciences, No. 5, Beixiange Street, Xicheng District, Beijing 100053, China. Ye, Yongming. Acupuncture Department, Guang&#039;anmen Hospital, China Academy of Chinese Medical Sciences, No. 5, Beixiange Street, Xicheng District, Beijing 100053, China. Liu, Jun. Acupuncture Department, Guang&#039;anmen Hospital, China Academy of Chinese Medical Sciences, No. 5, Beixiange Street, Xicheng District, Beijing 100053, China. Wang, Yang. Acupuncture Department, Guang&#039;anmen Hospital, China Academy of Chinese Medical Sciences, No. 5, Beixiange Street, Xicheng District, Beijing 100053, China. Peng, Weina. Acupuncture Department, Guang&#039;anmen Hospital, China Academy of Chinese Medical Sciences, No. 5, Beixiange Street, Xicheng District, Beijing 100053, China. Liu, Zhishun. Acupuncture Department, Guang&#039;anmen Hospital, China Academy of Chinese Medical Sciences, No. 5, Beixiange Street, Xicheng District, Beijing 100053, China.
AN  - 27725839
AU  - Yu,
AU  - J.
AU  - Ye,
AU  - Y.
AU  - Liu,
AU  - J.
AU  - Wang,
AU  - Y.
AU  - Peng,
AU  - W.
AU  - Liu,
AU  - Z.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1155/2016/1834646
DP  - Ovid Technologies
J2  - Evid Based Complement Alternat Med
L1  - internal-pdf://1588788033/Yu-2016-Acupuncture for Tourette Syndrome_ A S.pdf
LA  - English
M3  - Review
N1  - Yu, Jinna Ye, Yongming Liu, Jun Wang, Yang Peng, Weina Liu, Zhishun
PY  - 2016
SP  - 1834646
T2  - Evidence-Based Complementary and Alternative Medicine
TI  - Acupuncture for Tourette Syndrome: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27725839http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27725839&amp;id=doi:10.1155%2F2016%2F1834646&amp;issn=1741-427X&amp;isbn=&amp;volume=2016&amp;issue=&amp;spage=1834646&amp;pages=1834646&amp;date=2016&amp;title=Evidence-Based+Complementary+%26+Alternative+Medicine%3A+eCAM&amp;atitle=Acupuncture+for+Tourette+Syndrome%3A+A+Systematic+Review.&amp;aulast=Yu&amp;pid=%3Cauthor%3EYu+J%3C%2Fauthor%3E%3CAN%3E27725839%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048029/pdf/ECAM2016-1834646.pdf
VL  - 2016
ER  -
TY  - JOUR
AB  - Many unhealthy behaviors often begin during adolescence and represent major public health challenges. 

Substance abuse has a major impact on individuals, families, and communities, as its effects are cumulative, contributing to costly social, physical, and mental health problems. 

We conducted an overview of systematic reviews to evaluate the effectiveness of interventions to prevent substance abuse among adolescents. We report findings from a total of 46 systematic reviews focusing on interventions for smoking/tobacco use, alcohol use, drug use, and combined substance abuse. 

Our overview findings suggest that among smoking/tobacco interventions, school-based prevention programs and family-based intensive interventions typically addressing family functioning are effective in reducing smoking. Mass media campaigns are also effective given that these were of reasonable intensity over extensive periods of time. 

Among interventions for alcohol use, school-based alcohol prevention interventions have been associated with reduced frequency of drinking, while family-based interventions have a small but persistent effect on alcohol misuse among adolescents. For drug abuse, school-based interventions based on a combination of social competence and social influence approaches have shown protective effects against drugs and cannabis use. Among the interventions targeting combined substance abuse, school-based primary prevention programs are effective. 

Evidence from Internet-based interventions, policy initiatives, and incentives appears to be mixed and needs further research. Future research should focus on evaluating the effectiveness of specific interventions components with standardized intervention and outcome measures. Various delivery platforms, including digital platforms and policy initiative, have the potential to improve substance abuse outcomes among adolescents; however, these require further research. 

Copyright &copy; 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.
AD  - Das, Jai K. Division of Women and Child Health, Aga Khan University, Karachi, Pakistan. Salam, Rehana A. Division of Women and Child Health, Aga Khan University, Karachi, Pakistan. Arshad, Ahmed. Division of Women and Child Health, Aga Khan University, Karachi, Pakistan. Finkelstein, Yaron. Division of Emergency Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada; Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Ontario, Canada. Bhutta, Zulfiqar A. Centre for Global Child Health, The Hospital for Sick Children, Toronto, Ontario, Canada; Center of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan. Electronic address: zulfiqar.bhutta@sickkids.ca.
AN  - 27664597
AU  - Das,
AU  - J.
AU  - K.
AU  - Salam,
AU  - R.
AU  - A.
AU  - Arshad,
AU  - A.
AU  - Finkelstein,
AU  - Y.
AU  - Bhutta,
AU  - Z.
AU  - A.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jadohealth.2016.06.021
DP  - Ovid Technologies
J2  - J Adolesc Health
L1  - internal-pdf://0580304273/Das-2016-Interventions for Adolescent Substanc.pdf
LA  - English
M3  - Review
N1  - Das, Jai K Salam, Rehana A Arshad, Ahmed Finkelstein, Yaron Bhutta, Zulfiqar A S1054-139X(16)30167-7
PY  - 2016
SP  - S61-S75
T2  - Journal of Adolescent Health
TI  - Interventions for Adolescent Substance Abuse: An Overview of Systematic Reviews
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=27664597http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27664597&amp;id=doi:10.1016%2Fj.jadohealth.2016.06.021&amp;issn=1054-139X&amp;isbn=&amp;volume=59&amp;issue=4&amp;spage=S61&amp;pages=S61-S75&amp;date=2016&amp;title=Journal+of+Adolescent+Health&amp;atitle=Interventions+for+Adolescent+Substance+Abuse%3A+An+Overview+of+Systematic+Reviews.&amp;aulast=Das&amp;pid=%3Cauthor%3EDas+JK%3C%2Fauthor%3E%3CAN%3E27664597%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S1054139X16301677/1-s2.0-S1054139X16301677-main.pdf?_tid=27999dda-04c5-11e7-bd8a-00000aab0f26&amp;acdnat=1489063227_597acc9fbe10fb8e71cf7e892dac928a
VL  - 59
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
We performed meta-analyses of randomized controlled trials to examine the effects of neurofeedback on attention-deficit/hyperactivity disorder (ADHD) symptoms and neuropsychological deficits in children and adolescents with ADHD. 

**METHOD: **
We searched PubMed, Ovid, Web of Science, ERIC, and CINAHAL through August 30, 2015. Random-effects models were employed. Studies were evaluated with the Cochrane Risk of Bias tool. 

**RESULTS: **
We included 13 trials (520 participants with ADHD). Significant effects were found on ADHD symptoms rated by assessors most proximal to the treatment setting, that is, the least blinded outcome measure (standardized mean difference [SMD]: ADHD total symptoms = 0.35, 95% CI = 0.11-0.59; inattention = 0.36, 95% CI = 0.09-0.63; hyperactivity/impulsivity = 0.26, 95% CI = 0.08-0.43). Effects were not significant when probably blinded ratings were the outcome or in trials with active/sham controls. Results were similar when only frequency band training trials, the most common neurofeedback approach, were analyzed separately. Effects on laboratory measures of inhibition (SMD = 0.30, 95% CI = -0.10 to 0.70) and attention (SMD = 0.13, 95% CI = -0.09 to 0.36) were not significant. Only 4 studies directly assessed whether learning occurred after neurofeedback training. The risk of bias was unclear for many Cochrane Risk of Bias domains in most studies. 

**CONCLUSION: **
Evidence from well-controlled trials with probably blinded outcomes currently fails to support neurofeedback as an effective treatment for ADHD. Future efforts should focus on implementing standard neurofeedback protocols, ensuring learning, and optimizing clinically relevant transfer. 

Copyright &copy; 2016 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
AD  - Cortese, Samuele. Academic Unit of Psychology, Developmental Brain-Behaviour Laboratory, University of Southampton, Southampton, UK; New York University Child Study Center, New York, and Solent NHS Trust, UK. Ferrin, Maite. Academic Unit of Psychology, Developmental Brain-Behaviour Laboratory, University of Southampton, Southampton, UK; Huntercombe Hospital Maidenhead, Maidenhead, UK. Brandeis, Daniel. Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Psychiatric Hospital, University of Zurich, the Integrative Human Physiology and the Neuroscience Center Zurich, University of Zurich, Switzerland, and ETH Zurich. Holtmann, Martin. LWL-University Hospital for Child and Adolescent Psychiatry, Ruhr University Bochum, Germany. Aggensteiner, Pascal. Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Daley, David. School of Medicine and MindTech Institute of Mental Health, University of Nottingham, UK. Santosh, Paramala. Institute of Psychiatry, Psychology and Neurosciences, King&#039;s College London, and the Maudsley Hospital, London, UK. Simonoff, Emily. Institute of Psychiatry, Psychology and Neurosciences, King&#039;s College London, and the Maudsley Hospital, London, UK. Stevenson, Jim. Academic Unit of Psychology, Developmental Brain-Behaviour Laboratory, University of Southampton, Southampton, UK. Stringaris, Argyris. Institute of Psychiatry, Psychology and Neurosciences, King&#039;s College London, and the Maudsley Hospital, London, UK. Sonuga-Barke, Edmund J S. Academic Unit of Psychology, Developmental Brain-Behaviour Laboratory, University of Southampton, Southampton, UK; Ghent University, Ghent, Belgium and Aarhus University, Aarhus, Denmark. Electronic address: ejb3@soton.ac.uk.
AN  - 27238063
AU  - Cortese,
AU  - S.
AU  - Ferrin,
AU  - M.
AU  - Brandeis,
AU  - D.
AU  - Holtmann,
AU  - M.
AU  - Aggensteiner,
AU  - P.
AU  - Daley,
AU  - D.
AU  - Santosh,
AU  - P.
AU  - Simonoff,
AU  - E.
AU  - Stevenson,
AU  - J.
AU  - Stringaris,
AU  - A.
AU  - Sonuga-Barke,
AU  - E.
AU  - J.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2016.03.007
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
L1  - internal-pdf://3286284291/Cortese-2016-Neurofeedback for Attention-Defic.pdf
LA  - English
M3  - Review
N1  - (EAGG) Cortese, Samuele Ferrin, Maite Brandeis, Daniel Holtmann, Martin Aggensteiner, Pascal Daley, David Santosh, Paramala Simonoff, Emily Stevenson, Jim Stringaris, Argyris Sonuga-Barke, Edmund J S European ADHD Guidelines Group (EAGG) Asherson P Banaschewski T Brandeis D Buitelaar J Coghill D Cortese S Daley D Danckaerts M Dittmann RW Dopfner M Ferrin M Hollis C Holtmann M Konofal E Lecendreux M Rothenberger A Santosh P Sergeant JA Simonoff E Sonuga-Barke EJ Soutullo C Steinhausen H Stevenson J Stringaris A Taylor E van der Oord S Wong I Zuddas A S0890-8567(16)30095-8
PY  - 2016
SP  - 444-55
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Neurofeedback for Attention-Deficit/Hyperactivity Disorder: Meta-Analysis of Clinical and Neuropsychological Outcomes From Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27238063http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27238063&amp;id=doi:10.1016%2Fj.jaac.2016.03.007&amp;issn=0890-8567&amp;isbn=&amp;volume=55&amp;issue=6&amp;spage=444&amp;pages=444-55&amp;date=2016&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Neurofeedback+for+Attention-Deficit%2FHyperactivity+Disorder%3A+Meta-Analysis+of+Clinical+and+Neuropsychological+Outcomes+From+Randomized+Controlled+Trials.&amp;aulast=Cortese&amp;pid=%3Cauthor%3ECortese+S%3C%2Fauthor%3E%3CAN%3E27238063%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0890856716300958/1-s2.0-S0890856716300958-main.pdf?_tid=30a6f8f0-04c5-11e7-8d23-00000aab0f26&amp;acdnat=1489063243_ffa519f19f3c4ba13956c0c31a7bbc12
VL  - 55
ER  -
TY  - JOUR
AB  - **Objective: **
Violence is a leading cause of morbidity and mortality among young people. Primary preventive programs aimed at reducing the involvement of young people in violence are often implemented in a school setting. This systematic review evaluated the effectiveness of universal school-based programs aimed at the primary prevention of violence in 11- to 18-year-olds. 

**Method: **
A predefined search strategy was used to search various sources (i.e., databases, gray literature, previous reviews, and reference lists of included studies) for randomized design trials and quasi-experimental design trials published between 2002 and March 2014. After screening 8,051 abstracts, 21 studies that satisfied the inclusion and exclusion criteria were identified. These studies evaluated 16 different programs based mainly in the United States. 

**Results: **
Due to the heterogeneity, a meta-analysis was not possible; thus, a narrative synthesis was reported. The most effective interventions utilized social development and social norms components. Attitudes toward violence was the most frequently measured outcome, with 6 studies reporting a beneficial effect and 2 reporting no effect; 3 of the 6 studies examining violent behavior demonstrated a small beneficial effect; and 4 of the 7 studies examining physical aggression demonstrated a small beneficial effect. 

**Conclusions: **
In general, this review found limited evidence of the effectiveness of universal school-based programs in the primary prevention of violence in 11- to 18-year-olds; however, those that combined social development and social norms approaches appeared to be the most effective. Additional qualitative research and process evaluation is required to establish the processes that underpin the success or failure of such programs in order to inform their refinement and the future development of effective programs. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Gavine, Anna J.: a.gavine@dundee.ac.uk Gavine, Anna J.: School of Nursing and Health Sciences, University of Dundee, 11 Airlie Place, Dundee, United Kingdom, DD1 4HJ, a.gavine@dundee.ac.uk Gavine, Anna J.: School of Nursing and Health Sciences, University of Dundee, Dundee, United Kingdom Donnelly, Peter D.: School of Medicine, University of St Andrews, United Kingdom Williams, Damien J.: School of Medicine, University of St Andrews, United Kingdom
AN  - 2016-21282-001
AU  - Gavine,
AU  - A.
AU  - J.
AU  - Donnelly,
AU  - P.
AU  - D.
AU  - Williams,
AU  - D.
AU  - J.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/vio0000052
DP  - Ovid Technologies
KW  - youth violence, primary prevention, social development, social norms, systematic review
KW  - *Prevention
KW  - *School Based Intervention
KW  - *Violence
KW  - Psychosocial Development
KW  - Social Norms
KW  - Educational Psychology [3500]
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human
KW  - us
L1  - internal-pdf://0185200229/390.pdf
LA  - English
M3  - Literature Review; Systematic Review
N1  - Special Issue: Interventions for Violence
PY  - 2016
SP  - 390-399
T2  - Psychology of Violence
TI  - Effectiveness of universal school-based programs for prevention of violence in adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-21282-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2Fvio0000052&amp;issn=2152-0828&amp;isbn=1-4338-2664-X&amp;volume=6&amp;issue=3&amp;spage=390&amp;pages=390-399&amp;date=2016&amp;title=Psychology+of+Violence&amp;atitle=Effectiveness+of+universal+school-based+programs+for+prevention+of+violence+in+adolescents.&amp;aulast=Gavine&amp;pid=%3Cauthor%3EGavine%2C+Anna+J%3C%2Fauthor%3E%3CAN%3E2016-21282-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 6
ER  -
TY  - JOUR
AB  - A systematic review and meta-analysis of randomized controlled trials (RCT) was conducted to determine whether early interventions are effective in improving attachment security and parental sensitivity. 

Electronic databases were searched 2002-2015 onwards, All RCTs delivered to mothers, fathers or carers, before their child&#039;s mean age was 36 months, via 1:1 support, group work or guided self-help were included. The search was restricted to English Language publications. Study Selection, data extraction and quality appraisal were independently undertaken by two authors. 

With regard to analysis, where appropriate, dichotomous data were pooled using the Mantel- Haenszel odds ratio method and for continuous data descriptive statistics were collected in order to calculate standardized mean differences and effect sizes. Four studies met inclusion criteria and were divided into two groups: North American &amp; Canadian and South African based studies. 

Combining data from both groups indicates that early interventions improve attachment security and improves rates of disorganized attachment. 

One study provided extractable data on the outcome of parental sensitivity which shows that early interventions were effective in improving maternal sensitivity at 6 and 12 months. 

Study results generally support the findings of a previous review (Bakermans-Kranenburg et al., 2003) which found that early interventions improved attachment security and maternal sensitivity. 

Copyright &copy; 2016 Elsevier Inc. All rights reserved.
AD  - Mountain, Gary. School of Healthcare, University of Leeds, United Kingdom. Electronic address: g.mountain@leeds.ac.uk. Cahill, Jane. School of Healthcare, University of Leeds, United Kingdom. Thorpe, Helen. CAHMS Community Services, Rotherham, Doncaster &amp; South Humber NHS Foundation Trust, United Kingdom.
AN  - 27870988
AU  - Mountain,
AU  - G.
AU  - Cahill,
AU  - J.
AU  - Thorpe,
AU  - H.
DA  - Nov 18
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.infbeh.2016.10.006
DP  - Ovid Technologies
J2  - Infant behav
L1  - internal-pdf://2651162457/Mountain-2016-Sensitivity and attachment inter.pdf
LA  - English
N1  - Mountain, Gary Cahill, Jane Thorpe, Helen S0163-6383(15)30153-3
PY  - 2016
SP  - 14-32
T2  - Infant Behavior and Development
TI  - Sensitivity and attachment interventions in early childhood: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=27870988http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27870988&amp;id=doi:10.1016%2Fj.infbeh.2016.10.006&amp;issn=0163-6383&amp;isbn=&amp;volume=46&amp;issue=&amp;spage=14&amp;pages=14-32&amp;date=2016&amp;title=Infant+Behavior+%26+Development&amp;atitle=Sensitivity+and+attachment+interventions+in+early+childhood%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Mountain&amp;pid=%3Cauthor%3EMountain+G%3C%2Fauthor%3E%3CAN%3E27870988%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0163638315301533/1-s2.0-S0163638315301533-main.pdf?_tid=c2f79eec-0599-11e7-9cf2-00000aab0f27&amp;acdnat=1489154541_79b2c31deac4a956ff854afca12ee8d4
VL  - 46
ER  -
TY  - JOUR
AB  - Physical activity interventions are often implemented in the adolescent mental health care practice to prevent or treat psychosocial problems. 

To date, no systematic review of the effect of these physical activity interventions in adolescents has been conducted. In the current study, four multilevel meta-analyses were performed to assess the overall effect of physical activity interventions on externalizing problems, internalizing problems, self-concept, and academic achievement in adolescents. In addition, possible moderating factors were examined. 

In total, 57 studies reporting on 216 effect sizes were included, and the results showed significant small-to-moderate effects of physical activity interventions on externalizing problems (d=0.320), internalizing problems (d=0.316), self-concept (d=0.297), and academic achievement (d=0.367). 

Further, moderator analyses showed that outcome, study, sample, and intervention characteristics influenced the effects of physical activity interventions on psychosocial outcomes. Implications for theory and practice concerning the use of physical activity interventions in adolescent mental health care practice are discussed. 

Copyright &copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Spruit, Anouk. Research Institute of Child Development and Education, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS Amsterdam, The Netherlands. Electronic address: a.spruit@uva.nl. Assink, Mark. Research Institute of Child Development and Education, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS Amsterdam, The Netherlands. Electronic address: m.assink@uva.nl. van Vugt, Eveline. Research Institute of Child Development and Education, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS Amsterdam, The Netherlands. Electronic address: e.s.vanvugt@uva.nl. van der Put, Claudia. Research Institute of Child Development and Education, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS Amsterdam, The Netherlands. Electronic address: c.e.vanderput@uva.nl. Stams, Geert Jan. Research Institute of Child Development and Education, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS Amsterdam, The Netherlands. Electronic address: g.j.j.m.stams@uva.nl.
AN  - 27064552
AU  - Spruit,
AU  - A.
AU  - Assink,
AU  - M.
AU  - van
AU  - Vugt,
AU  - E.
AU  - van
AU  - der
AU  - Put,
AU  - C.
AU  - Stams,
AU  - G.
AU  - J.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2016.03.006
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://2042283403/Spruit-2016-The effects of physical activity i.pdf
LA  - English
M3  - Review
N1  - Spruit, Anouk Assink, Mark van Vugt, Eveline van der Put, Claudia Stams, Geert Jan S0272-7358(15)30133-1
PY  - 2016
SP  - 56-71
T2  - Clinical Psychology Review
TI  - The effects of physical activity interventions on psychosocial outcomes in adolescents: A meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27064552http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27064552&amp;id=doi:10.1016%2Fj.cpr.2016.03.006&amp;issn=0272-7358&amp;isbn=&amp;volume=45&amp;issue=&amp;spage=56&amp;pages=56-71&amp;date=2016&amp;title=Clinical+Psychology+Review&amp;atitle=The+effects+of+physical+activity+interventions+on+psychosocial+outcomes+in+adolescents%3A+A+meta-analytic+review.&amp;aulast=Spruit&amp;pid=%3Cauthor%3ESpruit+A%3C%2Fauthor%3E%3CAN%3E27064552%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0272735815301331/1-s2.0-S0272735815301331-main.pdf?_tid=444dc356-04d0-11e7-a72d-00000aacb361&amp;acdnat=1489068000_fc7ba70f4304560d552ac368d8dc1f11
VL  - 45
ER  -
TY  - JOUR
AB  - **PURPOSE OF THE RESEARCH: **
Burgeoning evidence that modifiable parental factors can influence children&#039;s and adolescents&#039; risk for depression and anxiety indicates that parents can play a crucial role in prevention of these disorders in their children. However, it remains unclear whether preventive interventions that are directed primarily at the parent (i.e. where the parent receives more than half of the intervention) are effective in reducing child internalizing (including both depression and anxiety) problems in the longer term. 

**PRINCIPAL RESULTS: **
Compared to a range of comparison conditions, parenting interventions reduced child internalizing problems, at a minimum of 6months after the intervention was delivered. Mean effects were very small for measures of internalizing and depressive symptoms, and small for measures of anxiety symptoms. Pooled effects for anxiety diagnoses were significant and indicated a number needed to treat (NNT) of 10. Pooled effects for depression diagnoses approached significance but suggested a NNT of 11. These results were based on effects reported at the longest follow-up interval for each included study, which ranged from 6months up to 15years for internalizing measures, 5.5years for depressive measures, and 11years for anxiety measures.

**MAJOR CONCLUSIONS:**
Our findings underscore the likely benefits of increasing parental involvement in preventing internalizing problems, particularly anxiety problems, in young people. 

Copyright &copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Yap, Marie B H. School of Psychological Sciences, Monash Institute of Cognitive and Clinical Neurosciences, Monash University, Melbourne, Australia; Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia. Electronic address: marie.yap@monash.edu. Morgan, Amy J. Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia; School of Psychology and Public Health, La Trobe University, Melbourne, Australia. Cairns, Kathryn. Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia. Jorm, Anthony F. Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia. Hetrick, Sarah E. Centre of Excellence in Youth Mental Health, Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Melbourne, Australia. Merry, Sally. School of Medicine, University of Auckland, New Zealand.
AN  - 27969003
AU  - Yap,
AU  - M.
AU  - B.
AU  - Morgan,
AU  - A.
AU  - J.
AU  - Cairns,
AU  - K.
AU  - Jorm,
AU  - A.
AU  - F.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Merry,
AU  - S.
DA  - Oct 21
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2016.10.003
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://2074999039/Yap-2016-Parents in prevention_ A meta-analysi.pdf
LA  - English
M3  - Review
N1  - Yap, Marie B H Morgan, Amy J Cairns, Kathryn Jorm, Anthony F Hetrick, Sarah E Merry, Sally S0272-7358(15)30117-3
PY  - 2016
SP  - 138-158
T2  - Clinical Psychology Review
TI  - Parents in prevention: A meta-analysis of randomized controlled trials of parenting interventions to prevent internalizing problems in children from birth to age 18
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=27969003http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27969003&amp;id=doi:10.1016%2Fj.cpr.2016.10.003&amp;issn=0272-7358&amp;isbn=&amp;volume=50&amp;issue=&amp;spage=138&amp;pages=138-158&amp;date=2016&amp;title=Clinical+Psychology+Review&amp;atitle=Parents+in+prevention%3A+A+meta-analysis+of+randomized+controlled+trials+of+parenting+interventions+to+prevent+internalizing+problems+in+children+from+birth+to+age+18.&amp;aulast=Yap&amp;pid=%3Cauthor%3EYap+MB%3C%2Fauthor%3E%3CAN%3E27969003%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0272735815301173/1-s2.0-S0272735815301173-main.pdf?_tid=7d71aefc-04d2-11e7-84f6-00000aab0f6b&amp;acdnat=1489068955_e9a1c8b6c1d2f9d5477e37a877317119
VL  - 50
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
econd-generation antipsychotics are commonly prescribed for pediatric patients with schizophrenia and schizophrenia spectrum disorders despite their lack of approval for use in children. Although considered a safer alternative to first-generation antipsychotics, there is evidence to suggest that second-generation antipsychotics may be associated with some adverse events as well as an increase in prolactin levels. The purpose of this review is to examine the risk of prolactin-related adverse events in pediatric patients using antipsychotics and to quantify changes in prolactin for this population. 

**METHODS: **
Literature searches were conducted in Medline, Embase, the Cochrane Central Register of Controlled Trials, and PsycINFO databases, supplemented with review of select gray literature to identify both randomized controlled trials and observational studies on pediatric patients prescribed antipsychotic medications for schizophrenia or schizophrenia spectrum disorders. Using a narrative approach, data on adverse events were recorded and changes from baseline in prolactin were pooled, where possible, from the randomized trials. Change from baseline in prolactin was evaluated for each treatment, as well as in comparison to placebo and to other treatments. Where data was available, these changes were evaluated separately for male and female patients. 

**RESULTS: **
Six randomized controlled trials and five observational studies, all examining the effects of second-generation antipsychotics, were selected. Literature reporting the effects of risperidone, quetiapine, aripiprazole, olanzapine, and paliperidone was identified, with varying doses. Prolactin-related adverse events were sparsely reported across studies. In evidence gathered from randomized controlled trials, risperidone, olanzapine, and two doses of paliperidone (3-5 mg/day and 6-12 mg/day) were associated with increased prolactin levels compared to baseline. With the exception of paliperidone, similar trends were observed in males and females, separately. The findings of the observational evidence served to both complement and run contrary to the randomized trials, with discrepancies attributed to differences in patient and treatment characteristics. 

**CONCLUSIONS: **
No definitive conclusions between second-generation antipsychotic use and prolactin-related adverse events can be made based on the available literature. While some trends in prolactin level changes emerged, this was based on few trials with small sample sizes. Future investigations should emphasize reporting on treatment safety. 

Trial registration: prospero crd42014009506 .
AD  - Druyts, Eric. Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada. edruyts@gmail.com. Zoratti, Michael J. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada. Toor, Kabirraaj. Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada. Wu, Ping. Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada. Kanji, Salmaan. Department of Pharmacy of the Ottawa Hospital, Ottawa Hospital Research Institute, Ottawa, ON, Canada. Rabheru, Kiran. Department of Psychiatry, Ottawa Hospital, Ottawa, ON, Canada. Mills, Edward J. Faculty of Health Sciences, University of Ottawa, Ottawa, ON, Canada. Thorlund, Kristian. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada.
AN  - 27825323
AU  - Druyts,
AU  - E.
AU  - Zoratti,
AU  - M.
AU  - J.
AU  - Toor,
AU  - K.
AU  - Wu,
AU  - P.
AU  - Kanji,
AU  - S.
AU  - Rabheru,
AU  - K.
AU  - Mills,
AU  - E.
AU  - J.
AU  - Thorlund,
AU  - K.
DA  - Nov 09
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/s12887-016-0710-y
DP  - Ovid Technologies
J2  - BMC Pediatr
L1  - internal-pdf://4003385547/Druyts-2016-Prolactin-related adverse events a.pdf
LA  - English
N1  - Druyts, Eric Zoratti, Michael J Toor, Kabirraaj Wu, Ping Kanji, Salmaan Rabheru, Kiran Mills, Edward J Thorlund, Kristian 10.1186/s12887-016-0710-y
PY  - 2016
SP  - 181
T2  - BMC Pediatrics
TI  - Prolactin-related adverse events and change in prolactin levels in pediatric patients given antipsychotics for schizophrenia and schizophrenia spectrum disorders: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27825323http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27825323&amp;id=doi:10.1186%2Fs12887-016-0710-y&amp;issn=1471-2431&amp;isbn=&amp;volume=16&amp;issue=1&amp;spage=181&amp;pages=181&amp;date=2016&amp;title=BMC+Pediatrics&amp;atitle=Prolactin-related+adverse+events+and+change+in+prolactin+levels+in+pediatric+patients+given+antipsychotics+for+schizophrenia+and+schizophrenia+spectrum+disorders%3A+A+systematic+review.&amp;aulast=Druyts&amp;pid=%3Cauthor%3EDruyts+E%3C%2Fauthor%3E%3CAN%3E27825323%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101725/pdf/12887_2016_Article_710.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - **Background:** 
Adolescent substance use is a major problem in and of itself, and because it acts as a risk factor for other problem behaviours. As substance use during adolescence can lead to adverse and often long-term health and social consequences, it is important to intervene early in order to prevent progression to more severe problems. Brief interventions have been shown to reduce problematic substance use among adolescents and are especially useful for individuals who have moderately risky patterns of substance use. Such interventions can be conducted in school settings. This review set out to evaluate the effectiveness of brief school-based interventions for adolescent substance use.

**Objectives:** 
To evaluate the effectiveness of brief school-based interventions in reducing substance use and other behavioural outcomes among adolescents compared to another intervention or assessment-only conditions.

**Search methods:** 
We conducted the original literature search in March 2013 and performed the search update to February 2015. For both review stages (original and update), we searched 10 electronic databases and six websites on evidence-based interventions, and the reference lists of included studies and reviews, from 1966 to February 2015. We also contacted authors and organisations to identify any additional studies.

**Selection criteria:** 
We included randomised controlled trials that evaluated the effects of brief school-based interventions for substance-using adolescents.The primary outcomes were reduction or cessation of substance use. The secondary outcomes were engagement in criminal activity and engagement in delinquent or problem behaviours related to substance use.

**Data collection and analysis:** 
We used the standard methodological procedures outlined by The Cochrane Collaboration, including the GRADE approach for evaluating the quality of evidence.

**Main results:** 
We included six trials with 1176 adolescents that measured outcomes at different follow-up periods in this review. Three studies with 732 adolescents compared brief interventions (Bls) with information provision only, and three studies with 444 adolescents compared Bls with assessment only. Reasons for downgrading the quality of evidence included risk of bias of the included studies, imprecision, and inconsistency. For outcomes that concern substance abuse, the retrieved studies only assessed alcohol and cannabis. We generally found moderate-quality evidence that, compared to information provision only, BIs did not have a significant effect on any of the substance use outcomes at short-, medium-, or long-term follow-up. They also did not have a significant effect on delinquent-type behaviour outcomes among adolescents. When compared to assessment-only controls, we found low- or very low-quality evidence that BIs reduced cannabis frequency at short-term follow-up in one study (standardised mean difference (SMD) -0.83; 95% confidence interval (CI) -1.14 to -0.53, n = 269). BIs also significantly reduced frequency of alcohol use (SMD -0.91; 95% CI -1.21 to -0.61, n = 242), alcohol abuse (SMD -0.38; 95% CI -0.7 to -0.07, n = 190) and dependence (SMD -0.58; 95% CI -0.9 to -0.26, n = 190), and cannabis abuse (SMD -0.34; 95% CI -0.65 to -0.02, n = 190) at medium-term follow-up in one study. At long-term follow-up, BIs also reduced alcohol abuse (SMD -0.72; 95% CI -1.05 to -0.40, n = 181), cannabis frequency (SMD -0.56; 95% CI -0.75 to -0.36, n = 181), abuse (SMD -0.62; 95% CI -0.95 to -0.29, n = 181), and dependence (SMD -0.96; 95% CI -1.30 to -0.63, n = 181) in one study. However, the evidence from studies that compared brief interventions to assessment-only conditions was generally of low quality. Brief interventions also had mixed effects on adolescents&#039; delinquent or problem behaviours, although the effect at long-term follow-up on these outcomes in the assessment-only comparison was significant (SMD -0.78; 95% CI -1.11 to -0.45).

**Authors&#039; conclusions:** 
We found low- or very low-quality evidence that brief school-based interventions may be more effective in reducing a cohol and cannabis use than the assessment-only condition and that these reductions were sustained at long-term follow-up. We found moderate-quality evidence that, when compared to information provision, brief interventions probably did not have a significant effect on substance use outcomes. It is premature to make definitive statements about the effectiveness of brief school-based interventions for reducing adolescent substance use. Further high-quality studies examining the relative effectiveness of BIs for substance use and other problem behaviours need to be conducted, particularly in low- and middle-income countries.
AN  - CD008969
AU  - Carney,
AU  - T.
AU  - Myers,
AU  - B.
AU  - J.
AU  - Louw,
AU  - J.
AU  - Okwundu,
AU  - C.
AU  - I.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd008969
KW  - Schools
KW  - Adolescent Behavior [psychology]
KW  - Motivational Interviewing
KW  - Psychotherapy, Brief [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Substance-Related Disorders [rehabilitation]
KW  - Adolescent[checkword]
KW  - Humans[checkword]
KW  - Addictn
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Brief school-based interventions and behavioural outcomes for substance-using adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008969.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD008969.pub3/asset/CD008969.pdf?v=1&amp;t=iw7iyydf&amp;s=3abfee87be6815661fbe7a168837dc3d8a0c331b
ER  -
TY  - JOUR
AB  - Internet-delivered cognitive behavior therapy (ICBT) is a relatively novel treatment format with the potential to increase accessibility of evidence-based care. However, little is known about the feasibility and efficacy of ICBT in children and adolescents. 

We conducted a comprehensive systematic review and meta-analysis of ICBT for children and adolescents to provide an overview of the field and assess the efficacy of these interventions. A systematic literature search of six electronic databases was performed to identify ICBT intervention studies for children with a psychiatric condition, such as social anxiety disorder, or a somatic condition, such as chronic pain. 

Two reviewers independently rated study quality. Twenty-five studies, targeting 11 different disorders, were included in the review. Study quality and presentation of treatment variables, such as therapist time and treatment adherence, varied largely. Twenty-four studies (N=1882) were included in the meta-analysis and ICBT yielded moderate between-group effect sizes when compared with waitlist, g=0.62, 95% CI [0.41, 0.84]. 

The results suggest that CBT for psychiatric and somatic conditions in children and adolescents can be successfully adapted to an internet-delivered format. 

Copyright &copy; 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
AD  - Vigerland, Sarah. Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Stockholm Health Care Services, Stockholm County Council, Sweden. Electronic address: sarah.vigerland@ki.se. Lenhard, Fabian. Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Stockholm Health Care Services, Stockholm County Council, Sweden. Bonnert, Marianne. Stockholm Health Care Services, Stockholm County Council, Sweden; Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. Lalouni, Maria. Stockholm Health Care Services, Stockholm County Council, Sweden; Department of Psychology, Uppsala University, Uppsala, Sweden. Hedman, Erik. Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Osher center for integrative medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. Ahlen, Johan. Department of Psychology, Uppsala University, Uppsala, Sweden. Olen, Ola. Department of Medicine, Karolinska Institutet, Stockholm, Sweden. Serlachius, Eva. Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Stockholm Health Care Services, Stockholm County Council, Sweden. Ljotsson, Brjann. Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
AN  - 27668988
AU  - Vigerland,
AU  - S.
AU  - Lenhard,
AU  - F.
AU  - Bonnert,
AU  - M.
AU  - Lalouni,
AU  - M.
AU  - Hedman,
AU  - E.
AU  - Ahlen,
AU  - J.
AU  - Olen,
AU  - O.
AU  - Serlachius,
AU  - E.
AU  - Ljotsson,
AU  - B.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2016.09.005
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://2704466397/Vigerland-2016-Internet-delivered cognitive be.pdf
LA  - English
M3  - Review
N1  - Vigerland, Sarah Lenhard, Fabian Bonnert, Marianne Lalouni, Maria Hedman, Erik Ahlen, Johan Olen, Ola Serlachius, Eva Ljotsson, Brjann S0272-7358(15)30090-8
PY  - 2016
SP  - 1-10
T2  - Clinical Psychology Review
TI  - Internet-delivered cognitive behavior therapy for children and adolescents: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27668988http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27668988&amp;id=doi:10.1016%2Fj.cpr.2016.09.005&amp;issn=0272-7358&amp;isbn=&amp;volume=50&amp;issue=&amp;spage=1&amp;pages=1-10&amp;date=2016&amp;title=Clinical+Psychology+Review&amp;atitle=Internet-delivered+cognitive+behavior+therapy+for+children+and+adolescents%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Vigerland&amp;pid=%3Cauthor%3EVigerland+S%3C%2Fauthor%3E%3CAN%3E27668988%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0272735815300908/1-s2.0-S0272735815300908-main.pdf?_tid=7f2b6d74-04d1-11e7-a463-00000aacb35d&amp;acdnat=1489068528_e6b278f939102a397bc9cbb904215395
VL  - 50
ER  -
TY  - JOUR
AB  - There has been rapid global dissemination of parenting interventions, yet little is known about their effectiveness when transported to countries different from where they originated, or about factors influencing success. 

This is the first systematic attempt to address this issue, focusing on interventions for reducing child behavior problems. Stage 1 identified evidence-based parenting interventions showing robust effects in systematic reviews; Stage 2 identified trials of these interventions in a new country. 

Systematic review = meta-analysis of transported programs was followed by subgroup analyses by trial- and country-level cultural, resource, and policy factors. We found 17 transported trials of 4 interventions, originating in United States or Australia, tested in 10 countries in 5 regions, (n = 1,558 children). 

Effects on child behavior were substantial (SMD .71) in the (14) randomized trials, but nonsignificant in the (3) nonrandomized trials. Subgroup analyses of randomized trials found no association between effect size and participant or intervention factors (e.g., program brand, staffing). Interventions transported to &quot;western&quot; countries showed comparable effects to trials in origin countries; however, effects were stronger when interventions were transported to culturally more distant regions. 

Effects were higher in countries with survival-focused family = childrearing values than those ranked more individualistic. There were no differences in effects by country-level policy or resource factors. Contrary to common belief, parenting interventions appear to be at least as effective when transported to countries that are more different culturally, and in service provision, than those in which they were developed. Extensive adaptation did not appear necessary for successful transportation. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AD  - Gardner, Frances: frances.gardner@spi.ox.ac.uk Gardner, Frances: Centre for Evidence-Based Intervention, Department of Social Policy and Intervention, University of Oxford, Barnett House-32 Wellington Square, Oxford, United Kingdom, OX1 2ER, frances.gardner@spi.ox.ac.uk Gardner, Frances: Centre for Evidence-Based Intervention, Department of Social Policy andIntervention, University of Oxford, Oxford, United Kingdom Montgomery, Paul: Centre for Evidence-Based Intervention, Department of Social Policy andIntervention, University of Oxford, Oxford, United Kingdom Knerr, Wendy: Centre for Evidence-Based Intervention, Department of Social Policy andIntervention, University of Oxford, Oxford, United Kingdom
AN  - 2016-60809-006
AU  - Gardner,
AU  - F.
AU  - Montgomery,
AU  - P.
AU  - Knerr,
AU  - W.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/15374416.2015.1015134
DP  - Ovid Technologies
KW  - child problem behavior, evidence-based parenting programs, countries, family/childrearing
KW  - *Behavior Problems
KW  - *Evidence Based Practice
KW  - *Parenting
KW  - Countries
KW  - Health &amp; Mental Health Services [3370]
KW  - Human Childhood (birth-12 yrs) Preschool Age (2-5 yrs) School Age (6-12 yrs)
L1  - internal-pdf://3865176701/Transporting-Evidence-Based-Parenting-Programs.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 749-762
T2  - Journal of Clinical Child and Adolescent Psychology
TI  - Transporting evidence-based parenting programs for child problem behavior (age 3-10) between countries: Systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-60809-006http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F15374416.2015.1015134&amp;issn=1537-4416&amp;isbn=&amp;volume=45&amp;issue=6&amp;spage=749&amp;pages=749-762&amp;date=2016&amp;title=Journal+of+Clinical+Child+and+Adolescent+Psychology&amp;atitle=Transporting+evidence-based+parenting+programs+for+child+problem+behavior+%28age+3-10%29+between+countries%3A+Systematic+review+and+meta-analysis.&amp;aulast=Gardner&amp;pid=%3Cauthor%3EGardner%2C+Frances%3C%2Fauthor%3E%3CAN%3E2016-60809-006%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 45
ER  -
TY  - JOUR
AB  - The objective of this study was to evaluate the efficacy of psychological treatments for depression in pre-adolescent children, a disorder affecting 1-2 % of children in this age range. 

A systematic review of studies of psychological interventions to treat depressive disorder in pre-adolescent children (aged up to 12-years-old) was carried out. The primary outcome was level of depressive symptoms. Studies were found using Medline, PsycINFO, EMBASE and Web of Knowledge databases and selected on several criteria. Only randomised controlled trials were included. 

Where individual studies covered a broader age range (usually including adolescents up to age 18 years), authors of those studies were contacted and requested to provide individual patient level data for those aged 12 years and younger. 2822 abstracts were reviewed, and from these 124 full text articles were reviewed, yielding 7 studies for which we were able to access appropriate data for this review. 5 of these studies evaluated cognitive behaviour therapy (CBT). 

Combined results from these studies suggest that there is a lack of evidence that CBT is better than no treatment [standard mean difference -0.342 (95 % confidence interval -0.961, 0.278)], although the number of participants included in the trials was relatively small. The evidence for efficacy of family therapy and psychodynamic therapy is even more limited. The very limited number of participants in randomised controlled trials means that there is inconclusive evidence for the psychological treatment of depression in children aged 12 years and below. 

Given the prevalence and significant impact of this disorder, there is an urgent need to establish the effectiveness or otherwise of psychological intervention.
AD  - Forti-Buratti, M Azul. The Centre for Mental Health, Hammersmith Campus, Imperial College London, 7th Floor Commonwealth Building, Du Cane Road, London, W12 0NN, UK. Saikia, Rupalim. The Centre for Mental Health, Hammersmith Campus, Imperial College London, 7th Floor Commonwealth Building, Du Cane Road, London, W12 0NN, UK. Wilkinson, Esther L. The Centre for Mental Health, Hammersmith Campus, Imperial College London, 7th Floor Commonwealth Building, Du Cane Road, London, W12 0NN, UK. Ramchandani, Paul G. The Centre for Mental Health, Hammersmith Campus, Imperial College London, 7th Floor Commonwealth Building, Du Cane Road, London, W12 0NN, UK. p.ramchandani@imperial.ac.uk.
AN  - 26969618
AU  - Forti-Buratti,
AU  - M.
AU  - A.
AU  - Saikia,
AU  - R.
AU  - Wilkinson,
AU  - E.
AU  - L.
AU  - Ramchandani,
AU  - P.
AU  - G.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-016-0834-5
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
KW  - Child
KW  - Cognitive Therapy
KW  - Depression/di [Diagnosis]
KW  - Depression/px [Psychology]
KW  - *Depression/th [Therapy]
KW  - Depressive Disorder/di [Diagnosis]
KW  - Depressive Disorder/px [Psychology]
KW  - *Depressive Disorder/th [Therapy]
KW  - Family Therapy
KW  - Humans
KW  - *Psychotherapy/mt [Methods]
KW  - Treatment Outcome
L1  - internal-pdf://0671016190/Forti-2016-Psychological treatments for depres.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Forti-Buratti, M Azul Saikia, Rupalim Wilkinson, Esther L Ramchandani, Paul G 10.1007/s00787-016-0834-5
PY  - 2016
SP  - 1045-54
T2  - European Child &amp; Adolescent Psychiatry
TI  - Psychological treatments for depression in pre-adolescent children (12 years and younger): systematic review and meta-analysis of randomised controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=mesx&amp;AN=26969618http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26969618&amp;id=doi:10.1007%2Fs00787-016-0834-5&amp;issn=1018-8827&amp;isbn=&amp;volume=25&amp;issue=10&amp;spage=1045&amp;pages=1045-54&amp;date=2016&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=Psychological+treatments+for+depression+in+pre-adolescent+children+%2812+years+and+younger%29%3A+systematic+review+and+meta-analysis+of+randomised+controlled+trials.&amp;aulast=Forti-Buratti&amp;pid=%3Cauthor%3EForti-Buratti+MA%3C%2Fauthor%3E%3CAN%3E26969618%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s00787-016-0834-5
UR  - http://download.springer.com/static/pdf/75/art%253A10.1007%252Fs00787-016-0834-5.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-016-0834-5&amp;token2=exp=1489074363~acl=%2Fstatic%2Fpdf%2F75%2Fart%25253A10.1007%25252Fs00787-016-0834-5.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-016-0834-5*~hmac=b067760f336d8c05d0d179d3d3991158f22097b835494d3acb1116a2ce801b48
VL  - 25
ER  -
TY  - JOUR
AB  - Children with intellectual disability frequently have difficulties in adapting to their environment. 

The extent of the experienced problems does not only depend on cognitive functioning but is influenced by other factors, such as the presence of a psychiatric disorder or other brain disorders, or adverse environmental factors. 

Several epidemiological studies show that children with intellectual disabilities are at an increased risk to develop psychiatric disorders. This is also true for youth with a mild intellectual disability and even those with borderline intellectual functioning (mild to borderline intellectual disability (MBID)). 

Psychiatric disorders are often overlooked because behavioral problems are rather attributed to the intellectual disability. Consequently, effective psychiatric interventions, which are needed to improve the level of functioning, are not applied.

This review aimed to systematically evaluate the currently available, qualitatively sound research concerning the effectiveness of psychosocial interventions, specifically directed at psychiatric disorders in children with MBID. Assessed for eligibility were 1409 unique reports, and the review ultimately included only 12 reports. 

Review of the results and meta-analyses showed that the majority of studies suffer from multiple limitations and that methodological variations between studies are extensive. This possibly reflects the high variance of factors that may be involved in MBID. It will be important in future research to address multi-causality.
AD  - [Kok, Lidwien; van der Waa, Anne] Karakter Child &amp; Youth Psychiat, Dept Mild Intellectual Disabil, NL-6862 BC Oosterbeek, Netherlands. [Klip, Helen; Staal, Wouter] Karakter Child &amp; Adolescent Psychiat Univ Ctr, Nijmegen, Netherlands. [Staal, Wouter] Radboud Univ Nijmegen, Dept Cognit Neurosci, Donders Inst Brain Cognit &amp; Behav, NL-6525 ED Nijmegen, Netherlands. Kok, L (reprint author), Karakter Child &amp; Youth Psychiat, Dept Mild Intellectual Disabil, Utrechtseweg 320, NL-6862 BC Oosterbeek, Netherlands. l.kok@karakter.com
AN  - WOS:000367466100012
AU  - Kok,
AU  - L.
AU  - van
AU  - der
AU  - Waa,
AU  - A.
AU  - Klip,
AU  - H.
AU  - Staal,
AU  - W.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1359104514567579
J2  - Clin. Child Psychol. Psychiatry
KW  - Mild intellectual disability
KW  - psychiatric disorder
KW  - psychosocial
KW  - intervention
KW  - parent training
KW  - borderline intellectual functioning
KW  - randomized controlled-trial
KW  - mental-retardation
KW  - developmental-disabilities
KW  - challenging behavior
KW  - treatment validity
KW  - adolescents
KW  - psychotherapy
KW  - prevalence
KW  - psychopathology
KW  - therapy
KW  - Psychology
KW  - Psychiatry
L1  - internal-pdf://3596495835/Kok-2016-The effectiveness of psychosocial int.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DA0DE Times Cited: 1 Cited Reference Count: 47 Kok, Lidwien van der Waa, Anne Klip, Helen Staal, Wouter 1 4 19 Sage publications inc Thousand oaks 1461-7021
PY  - 2016
SP  - 156-171
T2  - Clinical Child Psychology and Psychiatry
TI  - The effectiveness of psychosocial interventions for children with a psychiatric disorder and mild intellectual disability to borderline intellectual functioning: A systematic literature review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000367466100012
VL  - 21
ER  -
TY  - JOUR
AB  - Mental health problems in children can be precursors of psychosocial problems in adulthood. 

The aim of this study is to assess the effectiveness of the universal application of a resilience intervention (PRP and derivatives), which has been proposed for large scale roll-out. 

Electronic databases were searched for published randomized controlled trials of PRP and derivatives to prevent depression and anxiety and improve explanatory style in students aged 8-17 years. Studies were meta-analysed and effect sizes with confidence intervals were calculated. 

The Quality Assessment Tool for Quantitative Studies of the Effective Public Health Practice Project was used to determine the confidence in the effect estimates. Nine trials from Australia, the Netherlands and USA met the inclusion criteria. 

No evidence of PRP in reducing depression or anxiety and improving explanatory style was found. The large scale roll-out of PRP cannot be recommended. The content and structure of universal PRP should be re-considered. 

Copyright &copy; 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. 
All rights reserved.
AD  - Bastounis, Anastasios. School of Health Sciences, Queen&#039;s Medical Centre (QMC), University of Nottingham, Nottingham NG7 2UH, UK. Electronic address: ntxagb@exmail.nottingham.ac.uk. Callaghan, Patrick. School of Health Sciences, Queen&#039;s Medical Centre (QMC), University of Nottingham, Nottingham NG7 2UH, UK. Banerjee, Anirban. School of Health Sciences, Queen&#039;s Medical Centre (QMC), University of Nottingham, Nottingham NG7 2UH, UK. Michail, Maria. School of Health Sciences, Queen&#039;s Medical Centre (QMC), University of Nottingham, Nottingham NG7 2UH, UK.
AN  - 27494740
AU  - Bastounis,
AU  - A.
AU  - Callaghan,
AU  - P.
AU  - Banerjee,
AU  - A.
AU  - Michail,
AU  - M.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.adolescence.2016.07.004
DP  - Ovid Technologies
J2  - J Adolesc
L1  - internal-pdf://0267488148/Bastounis-2016-The effectiveness of the Penn R.pdf
LA  - English
N1  - Bastounis, Anastasios Callaghan, Patrick Banerjee, Anirban Michail, Maria S0140-1971(16)30068-9
PY  - 2016
SP  - 37-48
T2  - Journal of Adolescence
TI  - The effectiveness of the Penn Resiliency Programme (PRP) and its adapted versions in reducing depression and anxiety and improving explanatory style: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27494740http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27494740&amp;id=doi:10.1016%2Fj.adolescence.2016.07.004&amp;issn=0140-1971&amp;isbn=&amp;volume=52&amp;issue=&amp;spage=37&amp;pages=37-48&amp;date=2016&amp;title=Journal+of+Adolescence&amp;atitle=The+effectiveness+of+the+Penn+Resiliency+Programme+%28PRP%29+and+its+adapted+versions+in+reducing+depression+and+anxiety+and+improving+explanatory+style%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Bastounis&amp;pid=%3Cauthor%3EBastounis+A%3C%2Fauthor%3E%3CAN%3E27494740%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0140197116300689/1-s2.0-S0140197116300689-main.pdf?_tid=40e00cf0-04c2-11e7-b0c2-00000aacb35e&amp;acdnat=1489061981_df0ed53320c4890ee773cc5ae8f4d87e
VL  - 52
ER  -
TY  - JOUR
AB  - **Background:** 
Child overweight and obesity has increased globally, and can be associated with short- and long-term health consequences.

**Objectives:** 
To assess the effects of diet, physical activity, and behavioural interventions for the treatment of overweight or obesity in preschool children up to the age of 6 years.

**Search methods:** 
We performed a systematic literature search in the databases Cochrane Library, MEDLINE, EMBASE, PsycINFO, CINAHL, and LILACS, as well as in the trial registers ClinicalTrials.gov and ICTRP Search Portal. We also checked references of identified trials and systematic reviews. We applied no language restrictions. The date of the last search was March 2015 for all databases.Selection criteria: We selected randomised controlled trials (RCTs) of diet, physical activity, and behavioural interventions for treating overweight or obesity in preschool children aged 0 to 6 years.

**Data collection and analysis:** 
Two review authors independently assessed risk of bias, evaluated the overall quality of the evidence using the GRADE instrument, and extracted data following the Cochrane Handbook for Systematic Reviews of Interventions. We contacted trial authors for additional information.

**Main results:** 
We included 7 RCTs with a total of 923 participants: 529 randomised to an intervention and 394 to a comparator. The number of participants per trial ranged from 18 to 475. Six trials were parallel RCTs, and one was a cluster RCT. Two trials were three-arm trials, each comparing two interventions with a control group. The interventions and comparators in the trials varied. We categorised the comparisons into two groups: multicomponent interventions and dietary interventions. The overall quality of the evidence was low or very low, and six trials had a high risk of bias on individual &#039;Risk of bias&#039; criteria. The children in the included trials were followed up for between six months and three years.In trials comparing a multicomponent intervention with usual care, enhanced usual care, or information control, we found a greater reduction in body mass index (BMI) z score in the intervention groups at the end of the intervention (6 to 12 months): mean difference (MD) -0.3 units (95% confidence interval (CI) -0.4 to -0.2); P &lt; 0.00001; 210 participants; 4 trials; low-quality evidence, at 12 to 18 months&#039; follow-up: MD -0.4 units (95% CI -0.6 to -0.2); P = 0.0001; 202 participants; 4 trials; low-quality evidence, and at 2 years&#039; follow-up: MD -0.3 units (95% CI -0.4 to -0.1); 96 participants; 1 trial; low-quality evidence.One trial stated that no adverse events were reported; the other trials did not report on adverse events. Three trials reported health-related quality of life and found improvements in some, but not all, aspects. Other outcomes, such as behaviour change and parent-child relationship, were inconsistently measured.One three-arm trial of very low-quality evidence comparing two types of diet with control found that both the dairy-rich diet (BMI z score change MD -0.1 units (95% CI -0.11 to -0.09); P &lt; 0.0001; 59 participants) and energy-restricted diet (BMI z score change MD -0.1 units (95% CI -0.11 to -0.09); P &lt; 0.0001; 57 participants) resulted in greater reduction in BMI than the comparator at the end of the intervention period, but only the dairy-rich diet maintained this at 36 months&#039; follow-up (BMI z score change in MD -0.7 units (95% CI -0.71 to -0.69); P &lt; 0.0001; 52 participants). The energy-restricted diet had a worse BMI outcome than control at this follow-up (BMI z score change MD 0.1 units (95% CI 0.09 to 0.11); P &lt; 0.0001; 47 participants). There was no substantial difference in mean daily energy expenditure between groups. Health-related quality of life, adverse effects, participant views, and parenting were not measured.No trial reported on all-cause mortality, morbidity, or socioeconomic effects.All results should be interpreted cautiously due to their low quality and heterogeneous interventions and comparators.

**Authors&#039; conclusions:** 
Muticomponent interventions appear to be an effective tr a ment option for overweight or obese preschool children up to the age of 6 years. However, the current evidence is limited, and most trials had a high risk of bias. Most trials did not measure adverse events. We have identified four ongoing trials that we will include in future updates of this review.The role of dietary interventions is more equivocal, with one trial suggesting that dairy interventions may be effective in the longer term, but not energy-restricted diets. This trial also had a high risk of bias.
AN  - CD012105
AU  - Colquitt,
AU  - J.
AU  - L.
AU  - Loveman,
AU  - E.
AU  - O&#039;Malley,
AU  - C.
AU  - Azevedo,
AU  - L.
AU  - B.
AU  - Mead,
AU  - E.
AU  - Al-Khudairy,
AU  - L.
AU  - Ells,
AU  - L.
AU  - J.
AU  - Metzendorf,
AU  - M.
AU  - I.
AU  - Rees,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd012105
KW  - Body Mass Index
KW  - Behavior Therapy
KW  - Body Weight
KW  - Diet
KW  - Health Status
KW  - Motor Activity
KW  - Obesity [psychology] [therapy]
KW  - Overweight [psychology] [therapy]
KW  - Parent-Child Relations
KW  - Quality of Life
KW  - Randomized Controlled Trials as Topic
KW  - Self Concept
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Endoc
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Diet, physical activity, and behavioural interventions for the treatment of overweight or obesity in preschool children up to the age of 6 years
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD012105/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD012105/asset/CD012105.pdf?v=1&amp;t=iw7j9esi&amp;s=3c0f2788ded64419a06dbc44b28af052158fee14
ER  -
TY  - JOUR
AB  - **Syfte**

Syftet &auml;r att sammanst&auml;lla ett kunskapsst&ouml;d g&auml;llande nio specifika och namngivna program* vid institutionsvård av ungdomar med antisocial problematik.

1. Adolescent Community Reinforcement Approach (A-CRA)
2. Aggression Replacement Training (ART)
3. Dialectical Behavior Therapy/Dialektisk beteendeterapi (DBT)
4. Functional Family Therapy/Funktionell familjeterapi (FFT)
5. Multisystemic Therapy&ndash;Family Integrated Transitions (MST&ndash;FIT)
6. Parent Management Training (inklusive Komet)
7. Relapse Prevention/Återfallsprevention (RP)
8. Token Economy/Teckenekonomi (TE)
9. Structured Sensory Intervention for Traumatized Children, Adolescents and Parents for Adjudicated and At-Risk Youth (SITCAP-ART)

De flesta strukturerade behandlingsprogram f&ouml;r barn med antisocial problematik har utvecklats f&ouml;r att anv&auml;ndas inom &ouml;ppenvård, skola, familj eller annan n&auml;rmilj&ouml;. De har &auml;ven blivit utv&auml;rderade i sådana sammanhang. Exempel på program &auml;r Multisystemisk terapi (MST), Funktionell familjeterapi (FFT), Parent Management Training (PMTO, Triple P, De otroliga åren, Komet m.m.). Med undantag f&ouml;r ART (Aggression Replacement Training) så &auml;r det ytterst få program som har modifieringar anpassade till en institutionsmilj&ouml;. D&auml;rf&ouml;r &auml;r det inte så konstigt att det saknas utv&auml;rderingar av programmens effekter n&auml;r de anv&auml;nds inom institutionsvård.

**Slutsatser**
Det vetenskapliga underlaget &auml;r otillr&auml;ckligt f&ouml;r att bed&ouml;ma f&ouml;ljande program: ART, DBT, FFT, MST-FIT, PMT (inklusive Komet), RP, TE och SITCAP-ART. Det går d&auml;rf&ouml;r inte att avg&ouml;ra vilka effekter programmen har, j&auml;mf&ouml;rt med de alternativ som vanligtvis f&ouml;rekommer, n&auml;r det g&auml;ller institutionsplacerade ungdomar.

A-CRA (inklusive case manager) minskar risken f&ouml;r återfall i bruk av marijuana j&auml;mf&ouml;rt med vanligt f&ouml;rekommande alternativ, men det vetenskapliga underlaget &auml;r begr&auml;nsat.

Det saknas vetenskapligt underlag f&ouml;r att bed&ouml;ma relationen mellan programmens kostnader och effekter.

Vilka kan de praktiska konsekvenserna vara av dessa resultat? Avsaknaden av relevanta, tillf&ouml;rlitliga resultat beh&ouml;ver inte betyda att program b&ouml;r tas bort från befintlig verksamhet. Det betyder inte heller att man måste avstå från att inf&ouml;ra nya program som bed&ouml;ms som lovande. Det som kr&auml;vs &auml;r strukturerade former f&ouml;r hur man avvecklar, bibehåller eller inf&ouml;r program. Detta kan ske genom lokal uppf&ouml;ljning d&auml;r både positiva och eventuellt skadliga effekter utv&auml;rderas systematiskt.

**Resultat**
Underlaget inkluderar i sin helhet 17 studier, varav en redovisar svenska f&ouml;rhållanden. Dessa studier omfattar i sin tur data från cirka 1 680 ungdomar. F&ouml;r programmen FFT, PMT och RP saknas dock relevanta studier. F&ouml;r FFT och PMT beror detta på att dessa program inte avser institutionsvård. F&ouml;r återfallsprevention (RP) finns studier, men inte avseende den åldersgrupp som ingått i vårt uppdrag.

SBU:s kunskapssammanst&auml;llning visar att det vetenskapliga underlaget generellt sett &auml;r otillr&auml;ckligt f&ouml;r att kunna bed&ouml;ma effekten av de flesta program som anv&auml;nds vid institutionsvård av ungdomar med antisocial problematik. Detta betyder att valet mellan alternativa program inte kan avg&ouml;ras med st&ouml;d av det vetenskapliga underlag som sammanst&auml;llts i rapporten. Ist&auml;llet &auml;r d&auml;rf&ouml;r andra aspekter avg&ouml;rande f&ouml;r sådana val, till exempel bed&ouml;mning av de placerade ungdomarnas behov vid respektive institution, personalens kompetens, lokal, budget med mera.

**Diskussion**
Otillr&auml;ckligheten beror på alltf&ouml;r få individer per studie, oklarheter kring programinnehåll och kontrollvillkor, tveksamma eller oklara m&auml;tmetoder samt att metaanalyser inte har kunnat genomf&ouml;ras på grund av att studierna inte &auml;r tillr&auml;ckligt lika. Det s&auml;tt som studierna har lagts upp på har dessutom inte varit anpassat efter hur verksamheten bedrivs på institutionerna. Arbetss&auml;ttet på institutionerna inneb&auml;r att program och programkomponenter ingår i en helhet och d&auml;r målet &auml;r att anpassa de olika insatsernas innehåll och intensitet efter individens behov. I de flesta studierna utv&auml;rderades endast ett program d&auml;r det inte framgår om och i så fall på vilket s&auml;tt insatserna individanpassats.

Eftervårdsprogrammet Adolescent Community Reinforcement Approach (A-CRA) &auml;r ett undantag. J&auml;mf&ouml;rt med vanligt f&ouml;rekommande alternativ så minskar A-CRA (inklusive case manager) risken f&ouml;r återfall i marijuanabruk. Det vetenskapliga underlaget &auml;r dock begr&auml;nsat. Skattade effekter (inklusive den statistiska felmarginalen) &auml;r d&auml;rmed mycket os&auml;kra och nya forskningsresultat kan mycket v&auml;l f&ouml;r&auml;ndra bilden av hur effektiv A-CRA &auml;r. Sk&auml;len till de begr&auml;nsade resultaten &auml;r samma problem som f&ouml;r &ouml;vriga studier, med framf&ouml;r allt den skillnaden att två studier var m&ouml;jliga att v&auml;ga samman vilket medf&ouml;rde en st&ouml;rre statistisk teststyrka.

**Kunskapsluckor**
Det beh&ouml;vs forskning d&auml;r studieuppl&auml;gget &auml;r anpassat till hur verksamheten på institutionerna &auml;r sammansatt, med fokus på flera olika faktorer som påverkar beteendeproblemen. Studierna måste dessutom vara mer rigor&ouml;sa och omfatta betydligt fler individer j&auml;mf&ouml;rt med befintliga studier.Ungdomarnas antisociala problematik påverkas av många olika faktorer både i och utanf&ouml;r institutionen. De program som unders&ouml;kts i &ouml;versikten &auml;r inriktade på att f&ouml;r&auml;ndra några få faktorer. Inget program bygger på ett helhetsperspektiv d&auml;r avsikten &auml;r att påverka flera faktorer.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /sv/publikationer/SBU-utvarderar/program-for-ungdomar-med-antisocial-problematik-inom-institutionsvard/
L1  - internal-pdf://1136901251/program-for-ungdomar-med-antisocial-problemati.pdf
PY  - 2016
TI  - Program f&ouml;r ungdomar med antisocial problematik inom institutionsvård. En systematisk litteratur&ouml;versikt.
ER  -
TY  - JOUR
AB  - Many mental health disorders emerge in late childhood and early adolescence and contribute to the burden of these disorders among young people and later in life. 

We systematically reviewed literature published up to December 2015 to identify systematic reviews on mental health interventions in adolescent population. 

A total of 38 systematic reviews were included. We classified the included reviews into the following categories for reporting the findings: school-based interventions (n = 12); community-based interventions (n = 6); digital platforms (n = 8); and individual-/family-based interventions (n = 12). 

Evidence from school-based interventions suggests that targeted group-based interventions and cognitive behavioral therapy are effective in reducing depressive symptoms (standard mean difference [SMD]: -.16; 95% confidence interval [CI]: -.26 to -.05) and anxiety (SMD: -.33; 95% CI: -.59 to -.06). School-based suicide prevention programs suggest that classroom-based didactic and experiential programs increase short-term knowledge of suicide (SMD: 1.51; 95% CI: .57-2.45) and knowledge of suicide prevention (SMD: .72; 95% CI: .36-1.07) with no evidence of an effect on suicide-related attitudes or behaviors. Community-based creative activities have some positive effect on behavioral changes, self-confidence, self-esteem, levels of knowledge, and physical activity. 

Evidence from digital platforms supports Internet-based prevention and treatment programs for anxiety and depression; however, more extensive and rigorous research is warranted to further establish the conditions. Among individual- and family-based interventions, interventions focusing on eating attitudes and behaviors show no impact on body mass index (SMD: -.10; 95% CI: -.45 to .25); Eating Attitude Test (SMD: .01; 95% CI: -.13 to .15); and bulimia (SMD: -.03; 95% CI: -.16 to .10). Exercise is found to be effective in improving self-esteem (SMD: .49; 95% CI: .16-.81) and reducing depression score (SMD: -.66; 95% CI: -1.25 to -.08) with no impact on anxiety scores. Cognitive behavioral therapy compared to waitlist is effective in reducing remission (odds ratio: 7.85; 95% CI: 5.31-11.6). 

Psychological therapy when compared to antidepressants have comparable effect on remission, dropouts, and depression symptoms. The studies evaluating mental health interventions among adolescents were reported to be very heterogeneous, statistically, in their populations, interventions, and outcomes; hence, meta-analysis could not be conducted in most of the included reviews. 

Future trials should also focus on standardized interventions and outcomes for synthesizing the exiting body of knowledge. There is a need to report differential effects for gender, age groups, socioeconomic status, and geographic settings since the impact of mental health interventions might vary according to various contextual factors. 

Copyright &copy; 2016 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.
AD  - Das, Jai K. Division of Women and Child Health, Aga Khan University, Karachi, Pakistan. Salam, Rehana A. Division of Women and Child Health, Aga Khan University, Karachi, Pakistan. Lassi, Zohra S. Robinson Research Institute, University of Adelaide, Adelaide, Australia. Khan, Marium Naveed. Division of Women and Child Health, Aga Khan University, Karachi, Pakistan. Mahmood, Wajeeha. Ziauddin University, Karachi, Pakistan. Patel, Vikram. London School of Hygiene &amp; Tropical Medicine, London, United Kingdom; Public Health Foundation of India, New Delhi, India; Sangath, Goa, India. Bhutta, Zulfiqar A. Centre for Global Child Health, The Hospital for Sick Children, Toronto, Canada; Center of Excellence in Women and Child Health, The Aga Khan University, Karachi, Pakistan. Electronic address: zulfiqar.bhutta@sickkids.ca.
AN  - 27664596
AU  - Das,
AU  - J.
AU  - K.
AU  - Salam,
AU  - R.
AU  - A.
AU  - Lassi,
AU  - Z.
AU  - S.
AU  - Khan,
AU  - M.
AU  - N.
AU  - Mahmood,
AU  - W.
AU  - Patel,
AU  - V.
AU  - Bhutta,
AU  - Z.
AU  - A.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jadohealth.2016.06.020
DP  - Ovid Technologies
J2  - J Adolesc Health
L1  - internal-pdf://0094551800/Das-2016-Interventions for Adolescent Mental H.pdf
LA  - English
M3  - Review
N1  - Das, Jai K Salam, Rehana A Lassi, Zohra S Khan, Marium Naveed Mahmood, Wajeeha Patel, Vikram Bhutta, Zulfiqar A S1054-139X(16)30166-5
PY  - 2016
SP  - S49-S60
T2  - Journal of Adolescent Health
TI  - Interventions for Adolescent Mental Health: An Overview of Systematic Reviews
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=27664596http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27664596&amp;id=doi:10.1016%2Fj.jadohealth.2016.06.020&amp;issn=1054-139X&amp;isbn=&amp;volume=59&amp;issue=4&amp;spage=S49&amp;pages=S49-S60&amp;date=2016&amp;title=Journal+of+Adolescent+Health&amp;atitle=Interventions+for+Adolescent+Mental+Health%3A+An+Overview+of+Systematic+Reviews.&amp;aulast=Das&amp;pid=%3Cauthor%3EDas+JK%3C%2Fauthor%3E%3CAN%3E27664596%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S1054139X16301665/1-s2.0-S1054139X16301665-main.pdf?_tid=2bc34d52-04c5-11e7-90d0-00000aacb35f&amp;acdnat=1489063234_0632b52596b98043629054eff79e9783
VL  - 59
ER  -
TY  - JOUR
AB  - We conducted an overview of systematic reviews about child and adolescent anxiety treatment options (psychosocial; medication; combination; web/computer-based treatment) to support evidence informed decision-making. 

Three questions were addressed: (i) Is the treatment more effective than passive controls? (ii) Is there evidence that the treatment is superior to or non-inferior to (i.e., as good as) active controls? (iii) What is the quality of evidence for the treatment? Pre-specified inclusion criteria identified high quality systematic reviews (2000-2015) reporting treatment effects on anxiety diagnosis and symptom severity. 

Evidence quality (EQ) was rated using Oxford evidence levels [EQ1 (highest); EQ5 (lowest)]. Twenty-two of 39 eligible reviews were high quality (AMSTAR score&gt;3/5). CBT (individual or group, with or without parents) was more effective than passive controls (EQ1). CBT effects compared to active controls were mixed (EQ1). SSRI/SNRI were more effective than placebo (EQ1) but comparative effectiveness remains uncertain. EQ for combination therapy could not be determined. RCTs of web/computer-based interventions showed mixed results (EQ1). CBM/ABM was not more efficacious than active controls (EQ1). 

No other interventions could be rated. High quality RCTs support treatment with CBT and medication. Findings for combination and web/computer-based treatment are encouraging but further RCTs are required. Head-to-head comparisons of active treatment options are needed.
 Copyright &copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Bennett, Kathryn. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada. Electronic address: kbennett@mcmaster.ca. Manassis, Katharina. Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Duda, Stephanie. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada. Bagnell, Alexa. Department of Psychiatry, Dalhousie University and IWK Health Centre, Halifax, Nova Scotia, Canada. Bernstein, Gail A. Department of Psychiatry, University of Minnesota, Minneapolis, MN, United States. Garland, E Jane. Department of Psychiatry, University of British Columbia and BC Children&#039;s Hospital, Vancouver, British Columbia, Canada. Miller, Lynn D. Department of Educational and Counselling Psychology and Special Education, University of British Columbia, Vancouver, British Columbia, Canada. Newton, Amanda. Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada. Thabane, Lehana. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada. Wilansky, Pamela. Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
AN  - 27744168
AU  - Bennett,
AU  - K.
AU  - Manassis,
AU  - K.
AU  - Duda,
AU  - S.
AU  - Bagnell,
AU  - A.
AU  - Bernstein,
AU  - G.
AU  - A.
AU  - Garland,
AU  - E.
AU  - D.
AU  - Miller,
AU  - L.
AU  - D.
AU  - Newton,
AU  - A.
AU  - Thabane,
AU  - L.
AU  - Wilansky,
AU  - P.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2016.09.006
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://0896832215/Bennett-2016-Treating child and adolescent anx.pdf
LA  - English
M3  - Review
N1  - Bennett, Kathryn Manassis, Katharina Duda, Stephanie Bagnell, Alexa Bernstein, Gail A Garland, E Jane Miller, Lynn D Newton, Amanda Thabane, Lehana Wilansky, Pamela S0272-7358(16)30017-4
PY  - 2016
SP  - 80-94
T2  - Clinical Psychology Review
TI  - Treating child and adolescent anxiety effectively: Overview of systematic reviews
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27744168http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27744168&amp;id=doi:10.1016%2Fj.cpr.2016.09.006&amp;issn=0272-7358&amp;isbn=&amp;volume=50&amp;issue=&amp;spage=80&amp;pages=80-94&amp;date=2016&amp;title=Clinical+Psychology+Review&amp;atitle=Treating+child+and+adolescent+anxiety+effectively%3A+Overview+of+systematic+reviews.&amp;aulast=Bennett&amp;pid=%3Cauthor%3EBennett+K%3C%2Fauthor%3E%3CAN%3E27744168%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0272735816300174/1-s2.0-S0272735816300174-main.pdf?_tid=75e23b4e-04c2-11e7-84f6-00000aab0f6b&amp;acdnat=1489062070_f86eb0d11c7106b7d83f5bb0a94dcda5
VL  - 50
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Autism spectrum disorder (ASD) is increasingly recognized as a public health issue. Irritability and aggression (IA) often negatively affect the lives of people with ASD and their families. Although many medications have been tested for IA in ASDs in randomized controlled trials (RCTs), critical quantitative analyses of these trials are lacking in the literature. 

**OBJECTIVES: **
To systematically review and quantitatively analyze the efficacy and safety of pharmacologic treatments for IA in youth with ASD. 

**DATA SOURCES:**
Studies were identified from Medline, PsycINFO, Embase, and review articles. 

**METHODS: **
Original articles on placebo-controlled RCTs of pharmacologic treatments of IA in youth age 2 to 17 years with ASD were included. Data items included study design, study goals, details of study participants, details of intervention, study results, statistical methods, side effects, and risks of bias. The primary study outcome measure was the effect size of reduction in the Aberrant Behavioral Checklist-Irritability (ABC-I) scores in the medication group, as compared with placebo, in RCTs using parallel groups design. 

**RESULTS: **
Forty-six RCTs were identified. Compared with placebo, 3 compounds resulted in significant improvement in ABC-I at the end of treatment. Risperidone and aripiprazole were found to be the most effective, with the largest effect sizes. Sedation, extrapyramidal sides effects, and weight gain were assessed quantitatively. 

**CONCLUSIONS: **
Although risperidone and aripiprazole have the strongest evidence in reducing ABC-I in youth with ASD, a few other compounds also showed significant efficacy with fewer potential side effects and adverse reactions in single studies. 

Copyright &copy; 2016 by the American Academy of Pediatrics.
AD  - Fung, Lawrence K. Department of Psychiatry &amp; Behavioral Sciences, Stanford University, Stanford, California; Mahajan, Rajneesh. Kennedy Krieger Institute and Johns Hopkins University School of Medicine, Baltimore, Maryland; Nozzolillo, Alixandra. Center for Child &amp; Adolescent Health Research and Policy, MassGeneral Hospital for Children, Boston, Massachusetts; Bernal, Pilar. Kaiser Permanente Northern California, San Jose, California; Krasner, Aaron. New York-Presbyterian Hospital/Columbia University Medical Center, New York, New York; and. Jo, Booil. Department of Psychiatry &amp; Behavioral Sciences, Stanford University, Stanford, California; Coury, Daniel. Department of Developmental &amp; Behavioral Pediatrics, The Ohio State University, Columbus, Ohio. Whitaker, Agnes. New York-Presbyterian Hospital/Columbia University Medical Center, New York, New York; and. Veenstra-Vanderweele, Jeremy. New York-Presbyterian Hospital/Columbia University Medical Center, New York, New York; and. Hardan, Antonio Y. Department of Psychiatry &amp; Behavioral Sciences, Stanford University, Stanford, California; hardanay@stanford.edu.
AN  - 26908468
AU  - Fung,
AU  - L.
AU  - K.
AU  - Mahajan,
AU  - R.
AU  - Nozzolillo,
AU  - A.
AU  - Bernal,
AU  - P.
AU  - Krasner,
AU  - A.
AU  - Jo,
AU  - B.
AU  - Coury,
AU  - D.
AU  - Whitaker,
AU  - A.
AU  - Veenstra-Vanderweele,
AU  - J.
AU  - Hardan,
AU  - A.
AU  - Y.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2015-2851K
DP  - Ovid Technologies
J2  - Pediatrics
L1  - internal-pdf://1830807407/Fung-2016-Pharmacologic Treatment of Severe Ir.pdf
LA  - English
N1  - Fung, Lawrence K Mahajan, Rajneesh Nozzolillo, Alixandra Bernal, Pilar Krasner, Aaron Jo, Booil Coury, Daniel Whitaker, Agnes Veenstra-Vanderweele, Jeremy Hardan, Antonio Y peds.2015-2851K
PY  - 2016
SP  - S124-35
T2  - Pediatrics
TI  - Pharmacologic Treatment of Severe Irritability and Problem Behaviors in Autism: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26908468http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26908468&amp;id=doi:10.1542%2Fpeds.2015-2851K&amp;issn=0031-4005&amp;isbn=&amp;volume=137&amp;issue=2&amp;spage=S124&amp;pages=S124-35&amp;date=2016&amp;title=Pediatrics&amp;atitle=Pharmacologic+Treatment+of+Severe+Irritability+and+Problem+Behaviors+in+Autism%3A+A+Systematic+Review+and+Meta-analysis.&amp;aulast=Fung&amp;pid=%3Cauthor%3EFung+LK%3C%2Fauthor%3E%3CAN%3E26908468%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://pediatrics.aappublications.org/content/pediatrics/137/Supplement_2/S124.full.pdf
VL  - 137 Suppl 2
ER  -
TY  - JOUR
AB  - Obsessive-compulsive disorder (OCD) is ranked by the World Health Organization (WHO) among the 10 most debilitating disorders. The treatments which have been found effective are cognitive behavior therapy (CBT) and serotonin reuptake inhibitors (SRI). 

This meta-analysis includes all RCTs of CBT (25) and SRI (9) for OCD in youth using the Children&#039;s Yale-Brown Obsessive Compulsive Scale (C-YBOCS). CBT yielded significantly lower attrition (12.7%) than SRI (23.5%) and placebo (24.7%). The effect sizes for comparisons of CBT with waiting-list (1.53), placebo (0.93), and SRI with placebo (0.51) were significant, whereas CBT vs. SRI (0.22) and Combo (CBT+SRI) vs. CBT (0.14) were not. 

Regarding response rate CBT (70%) and Combo (66%) were significantly higher than SRI (49%), which was higher than placebo (29%) and WLC (13%). As for remission CBT (53%) and Combo (49%) were significantly higher than SRI (24%), placebo (15%), and WLC (10%), which did not differ from each other. Combo was not more effective than CBT alone irrespective of initial severity of the samples. 

The randomized controlled trials (RCTs) have a number of methodological problems and recommendations for improving research methodology are discussed as well as clinical implications of the findings. 

Copyright &copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Ost, Lars-Goran. Department of Clinical Neuroscience, The Karolinska Institute, Stockholm, Sweden; Department of Psychology, Stockholm University, Sweden; Department of Clinical Psychology, University of Bergen, Norway. Electronic address: ost@psychology.su.se. Riise, Eili N. Department of Clinical Psychology, University of Bergen, Norway; Haukeland University Hospital, OCD-team, 5021 Bergen, Norway. Wergeland, Gro Janne. Department of Child and Adolescent Psychiatry, Haukeland University Hospital, Bergen, Norway. Hansen, Bjarne. Department of Clinical Psychology, University of Bergen, Norway; Haukeland University Hospital, OCD-team, 5021 Bergen, Norway. Kvale, Gerd. Department of Clinical Psychology, University of Bergen, Norway; Haukeland University Hospital, OCD-team, 5021 Bergen, Norway.
AN  - 27632568
AU  - Ost,
AU  - L.
AU  - G.
AU  - Riise,
AU  - E.
AU  - N.
AU  - Wergeland,
AU  - G.
AU  - J.
AU  - Hansen,
AU  - B.
AU  - Kvale,
AU  - G.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.janxdis.2016.08.003
DP  - Ovid Technologies
J2  - J Anxiety Disord
L1  - internal-pdf://2468977439/Ost-2016-Cognitive behavioral and pharmacologi.pdf
LA  - English
M3  - Review
N1  - Ost, Lars-Goran Riise, Eili N Wergeland, Gro Janne Hansen, Bjarne Kvale, Gerd S0887-6185(16)30220-1
PY  - 2016
SP  - 58-69
T2  - Journal of Anxiety Disorders
TI  - Cognitive behavioral and pharmacological treatments of OCD in children: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27632568http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27632568&amp;id=doi:10.1016%2Fj.janxdis.2016.08.003&amp;issn=0887-6185&amp;isbn=&amp;volume=43&amp;issue=&amp;spage=58&amp;pages=58-69&amp;date=2016&amp;title=Journal+of+Anxiety+Disorders&amp;atitle=Cognitive+behavioral+and+pharmacological+treatments+of+OCD+in+children%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Ost&amp;pid=%3Cauthor%3EOst+LG%3C%2Fauthor%3E%3CAN%3E27632568%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0887618516302201/1-s2.0-S0887618516302201-main.pdf?_tid=c0a020aa-04cd-11e7-a3fc-00000aab0f01&amp;acdnat=1489066920_8f691687fc58749c5ea15311a99c8fa0
VL  - 43
ER  -
TY  - JOUR
AB  - The effectiveness of sex offender treatment programs continues to generate misinformation and disagreement. Some literature reviews conclude that treatment does not reduce recidivism while others suggest that specific types of treatment may warrant optimism. 

The principal purpose of this study is to update the most recent meta-analyses of sex offender treatments and to compare the findings with an earlier study that reviewed the meta-analytic studies published from 1995 to 2002. 

More importantly, this study examines effect sizes across different age populations and effect sizes across various sex offender treatments. 

Results of this review of meta-analyses suggest that sex offender treatments can be considered as &quot;proven&quot; or at least &quot;promising,&quot; while age of participants and intervention type may influence the success of treatment for sex offenders. 

The implications of these findings include achieving a broader understanding of intervention moderators, applying such interventions to juvenile and adult offenders, and outlining future areas of research. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Kim, Bitna: bitna.kim@iup.edu Kim, Bitna: Department of Criminology, Indiana University of Pennsylvania, Indiana, PA, US, 15705, bitna.kim@iup.edu Kim, Bitna: Department of Criminology, Indiana University of Pennsylvania, Indiana, PA, US Benekos, Peter J.: Criminal Justice Department, Mercyhurst University, Erie, PA, US Merlo, Alida V.: Department of Criminology, Indiana University of Pennsylvania, Indiana, PA, US
AN  - 2015-56294-007
AU  - Kim,
AU  - B.
AU  - Benekos,
AU  - P.
AU  - J
AU  - Merlo,
AU  - A.
AU  - V.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1524838014566719
DP  - Ovid Technologies
KW  - offenders, sexual assault, recidivism, intervention
KW  - *Criminal Rehabilitation
KW  - *Criminals
KW  - *Intervention
KW  - *Recidivism
KW  - *Sex Offenses
KW  - Behavior Disorders &amp; Antisocial Behavior [3230]
KW  - Human
L1  - internal-pdf://1208230548/Kim-2016-Sex offender recidivism revisited_ Re.pdf
LA  - English
M3  - Literature Review
PY  - 2016
SP  - 105-117
T2  - Trauma, Violence and Abuse
TI  - Sex offender recidivism revisited: Review of recent meta-analyses on the effects of sex offender treatment
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2015-56294-007http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1524838014566719&amp;issn=1524-8380&amp;isbn=&amp;volume=17&amp;issue=1&amp;spage=105&amp;pages=105-117&amp;date=2016&amp;title=Trauma%2C+Violence%2C+%26+Abuse&amp;atitle=Sex+offender+recidivism+revisited%3A+Review+of+recent+meta-analyses+on+the+effects+of+sex+offender+treatment.&amp;aulast=Kim&amp;pid=%3Cauthor%3EKim%2C+Bitna%3C%2Fauthor%3E%3CAN%3E2015-56294-007%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 17
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Stigmatizing attitudes toward mental illness and low mental health literacy have been identified as links to social adversity, and barriers to seeking and adhering to treatment among adolescents suffering from mental illness. Prior research has found that it is possible to improve these outcomes using school-based mental health awareness interventions. The purpose of this study was to review empirical literature pertaining to universal mental health awareness interventions aiming to improve mental health related outcomes among students enrolled in US K-12 schools, especially minorities vulnerable to health disparities. 

**METHODS: **
PsycINFO, Cochrane Library, PUBMED, and reference lists of relevant articles were searched for K-12 school-based mental health awareness interventions in the United States. Universal studies that measured knowledge, attitudes, and/or help-seeking pertinent to mental health were included. 

**RESULTS: **
A total of 15 studies were selected to be part of the review. There were 7 pretest/post-test case series, 5 nonrandomized experimental trial, 1 Solomon 4-groups, and 2 randomized controlled trial (RCT) designs. Nine studies measuring knowledge, 8 studies measuring attitudes, and 4 studies measuring help-seeking, indicated statistically significant improvements. 

**CONCLUSIONS: **
Although results of all studies indicated some level of improvement, more research on implementation of universal school-based mental health awareness programs is needed using RCT study designs, and long-term follow-up implementation. 

Copyright &copy; 2016, American School Health Association.
AD  - Salerno, John P. University of Miami - School of Nursing &amp; Health Studies, Center of Excellence for Health Disparities Research: El Centro, 5030 Brunson Drive, Coral Gables, FL 33146.
AN  - 27866385
AU  - Salerno,
AU  - J.
AU  - P.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/josh.12461
DP  - Ovid Technologies
J2  - J Sch Health
L1  - internal-pdf://0690926536/Salerno-2016-Effectiveness of Universal School.pdf
LA  - English
N1  - Salerno, John P
PY  - 2016
SP  - 922-931
T2  - Journal of School Health
TI  - Effectiveness of Universal School-Based Mental Health Awareness Programs Among Youth in the United States: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27866385http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27866385&amp;id=doi:10.1111%2Fjosh.12461&amp;issn=0022-4391&amp;isbn=&amp;volume=86&amp;issue=12&amp;spage=922&amp;pages=922-931&amp;date=2016&amp;title=Journal+of+School+Health&amp;atitle=Effectiveness+of+Universal+School-Based+Mental+Health+Awareness+Programs+Among+Youth+in+the+United+States%3A+A+Systematic+Review.&amp;aulast=Salerno&amp;pid=%3Cauthor%3ESalerno+JP%3C%2Fauthor%3E%3CAN%3E27866385%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1111/josh.12461/asset/josh12461.pdf?v=1&amp;t=j02g8yis&amp;s=3110a1bbb919201df2c10d89432fd32ee02dbef3
VL  - 86
ER  -
TY  - JOUR
AB  - Sleep complaints are common amongst mothers of infants and insufficient, inefficient or fragmented sleep is associated with postnatal depression. 

The aim of this review is to determine whether psychosocial sleep-focused interventions offered in the perinatal period improve infant sleep or maternal mood. We searched PubMed, PsycInfo, EMBASE and CINAHL with no date restriction. 

We reviewed 1097 articles, resulting in nine papers (n = 1,656) that fit the eligibility criteria for inclusion in the analyses. The primary outcome was infant sleep, defined as maternal reports of infant nocturnal total sleep time and number of night-time wakes. The secondary outcome was maternal mood. 

The meta-analysis indicated improvements in reported infant nocturnal total sleep time (Hedge&#039;s g = 0.204, p &lt; 0.01). However, there was no evidence for reducing infant night wakes (Hedge&#039;s g = 0.103, p = 0.134). There was evidence of maternal mood improvements (Hedge&#039;s g = 0.152, p = 0.014), however, this could have been influenced by publication bias. 

Psychosocial sleep interventions appear to impact the amount of sleep that a mother reports her baby to have, although the infants continue to wake as frequently. More research is needed to confirm whether sleep-related improvements can translate into improvements in maternal mood. 

Copyright &copy; 2015 Elsevier Ltd. All rights reserved.
AD  - Kempler, Liora. School of Psychology, University of Sydney, Australia; Woolcock Institute of Medical Research, Australia; The NHMRC Centres of Research Excellence, CIRUS and NEUROSLEEP, Australia. Electronic address: Liora.kempler@sydney.edu.au. Sharpe, Louise. School of Psychology, University of Sydney, Australia. Miller, Christopher B. Woolcock Institute of Medical Research, Australia; The NHMRC Centres of Research Excellence, CIRUS and NEUROSLEEP, Australia. Bartlett, Delwyn J. Woolcock Institute of Medical Research, Australia; The NHMRC Centres of Research Excellence, CIRUS and NEUROSLEEP, Australia.
AN  - 26555938
AU  - Kempler,
AU  - L.
AU  - Sharpe,
AU  - L.
AU  - Miller,
AU  - C.
AU  - B.
AU  - Bartlett,
AU  - D.
AU  - J.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.smrv.2015.08.002
DP  - Ovid Technologies
J2  - Sleep Med Rev
L1  - internal-pdf://4253949925/Kempler-2016-Do psychosocial sleep interventio.pdf
LA  - English
M3  - Review
N1  - Kempler, Liora Sharpe, Louise Miller, Christopher B Bartlett, Delwyn J S1087-0792(15)00100-8
PY  - 2016
SP  - 15-22
T2  - Sleep Medicine Reviews
TI  - Do psychosocial sleep interventions improve infant sleep or maternal mood in the postnatal period? A systematic review and meta-analysis of randomised controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26555938http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26555938&amp;id=doi:10.1016%2Fj.smrv.2015.08.002&amp;issn=1087-0792&amp;isbn=&amp;volume=29&amp;issue=&amp;spage=15&amp;pages=15-22&amp;date=2016&amp;title=Sleep+Medicine+Reviews&amp;atitle=Do+psychosocial+sleep+interventions+improve+infant+sleep+or+maternal+mood+in+the+postnatal+period%3F+A+systematic+review+and+meta-analysis+of+randomised+controlled+trials.&amp;aulast=Kempler&amp;pid=%3Cauthor%3EKempler+L%3C%2Fauthor%3E%3CAN%3E26555938%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S1087079215001008/1-s2.0-S1087079215001008-main.pdf?_tid=b459defc-04c9-11e7-bef2-00000aacb35e&amp;acdnat=1489065182_5f9a8c664502d447234205e796445f8b
VL  - 29
ER  -
TY  - JOUR
AB  - Working memory trainings have been proposed to remediate ADHD symptoms and to improve functioning by targeting the underlying neuropsychological deficits. However, relatively few studies have been written on analyzing the effects of working memory trainings in ADHD children, notwithstanding the relevant implications of gamified working memory trainings on cognitive processes. 

The main purpose of this meta-analytical review was to examine the effects of working memory trainings with game elements. The analysis of the 11 selected studies explored the availability of game elements to enhance cognitive performance of children with ADHD. 

Potential moderator factors were examined such as different types of interventions, the amount of game elements, type of outcome (three levels: cognitive, behavioral, socio- emotional and academic performance). 

Results indicated a small potential importance of game elements and little possible benefits of gamified working memory trainings. There is much uncertainty related to working memory trainings and ADHD.

(PsycINFO Database Record (c) 2018 APA, all rights reserved)
AN  - 2017-58753-001
AU  - Farcas,
AU  - S.
AU  - Szamoskozi,
AU  - I.
AU  - Takacs,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
L1  - internal-pdf://0149661000/Farcas-2016-The effects of working memory trai.pdf
PY  - 2016
SP  - 21-44
T2  - Erdelyi Pszichologiai Szemle
TI  - The effects of working memory trainings with game elements for children with ADHD. A meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc14&amp;AN=2017-58753-001
VL  - 17
ER  -
TY  - JOUR
AB  - **Background:** 
People with asthma have a higher prevalence of anxiety and depression than the general population. This is associated with poorer asthma control, medication adherence, and health outcomes. Cognitive behavioural therapy (CBT) may be a way to improve the quality of life of people with asthma by addressing associated psychological issues, which may lead to a lower risk of exacerbations and better asthma control.

**Objectives:** 
To assess the efficacy of CBT for asthma compared with usual care.Search methods: We searched the Cochrane Airways Group Specialised Register, ClinicalTrials.gov, and the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP). We also searched reference lists of all primary studies and review articles and contacted authors for unpublished data. The most recent searches were conducted in August 2016.

**Selection criteria:** 
We included parallel randomised controlled trials (RCTs) comparing any cognitive behavioural intervention to usual care or no intervention. We included studies of adults or adolescents with asthma, with or without comorbid anxiety or depression. We included studies reported as full text, those published as abstract only, and unpublished data.

**Data collection and analysis:** 
Two or more review authors independently screened the search results, extracted data, and assessed included studies for risk of bias. We analysed dichotomous data as odds ratios (ORs) and continuous data as mean differences (MDs) or standardised mean differences (SMD) where scales varied across studies, all using a random-effects model. The primary outcomes were asthma-related quality of life and exacerbations requiring at least a course of oral steroids. We rated all outcomes using GRADE and presented our confidence in the results in a &#039;Summary of findings&#039; table.

**Main results:** 
We included nine RCTs involving 407 adults with asthma in this review; no studies included adolescents under 18. Study size ranged from 10 to 94 (median 40), and mean age ranged from 39 to 53. Study populations generally had persistent asthma, but severity and diagnostic measures varied. Three studies recruited participants with psychological symptomatology, although with different criteria. Interventions ranged from 4 to 15 sessions, and primary measurements were taken at a mean of 3 months (range 1.2 to 12 months).Participants given CBT had improved scores on the Asthma Quality of Life Questionnaire (AQLQ) (MD 0.55, 95% confidence interval (CI) 0.17 to 0.93; participants = 214; studies = 6; I2 = 53%) and on measures of asthma control (SMD -0.98, 95% CI -1.76 to -0.20; participants = 95; studies = 3; I2 = 68%) compared to people getting usual care. The AQLQ effect appeared to be sustained up to a year after treatment, but due to its low quality this evidence must be interpreted with caution. As asthma exacerbations requiring at least a course of oral steroids were not consistently reported, we could not perform a meta-analysis.Anxiety scores were difficult to pool but showed a benefit of CBT compared with usual care (SMD -0.38, 95% CI -0.73 to -0.03), although this depended on the analysis used. The confidence intervals for the effect on depression scales included no difference between CBT and usual care when measured as change from baseline (SMD -0.33, 95% CI -0.70 to 0.05) or endpoint scores (SMD -0.41, 95% CI -0.87 to 0.05); the same was true for medication adherence (MD -1.40, 95% CI -2.94 to 0.14; participants = 23; studies = 1; I2 = 0%).Subgroup analyses conducted on the AQLQ outcome did not suggest a clear difference between individual and group CBT, baseline psychological status, or CBT model. The small number of studies and the variation between their designs, populations, and other intervention characteristics limited the conclusions that could be drawn about these possibly moderating factors.The inability to blind participants and investigators to group allocation introduced significant potential bias, and overall we had low confidence in the evidence.

**Authors&#039; conclusions:** 
For adults with pe s stent asthma, CBT may improve quality of life, asthma control, and anxiety levels compared with usual care. Risks of bias, imprecision of effects, and inconsistency between results reduced our confidence in the results to low, and evidence was lacking regarding the effect of CBT on asthma exacerbations, unscheduled contacts, depression, and medication adherence. There was much variation between studies in how CBT was delivered and what constituted usual care, meaning the most optimal method of CBT delivery, format, and target population requires further investigation. There is currently no evidence for the use of CBT in adolescents with asthma.
AN  - CD011818
AU  - Kew,
AU  - K.
AU  - M.
AU  - Nashed,
AU  - M.
AU  - Dulay,
AU  - V.
AU  - Yorke,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd011818.pub2
KW  - Airways
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive behavioural therapy (CBT) for adults and adolescents with asthma
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD011818.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD011818.pub2/asset/CD011818.pdf?v=1&amp;t=iw7j3lys&amp;s=250b06d9a1fe265e7f4b49615031a1360be51b30
ER  -
TY  - JOUR
AB  - Meta-analyses of the treatment of posttraumatic stress disorder (PTSD) in childhood and adolescence are restricted to specific trauma, selected interventions, and methodologically rigorous studies. This large meta-analysis quantifies the effects of psychological treatments for PTSD symptoms in children and adolescents. 

An extensive literature search yielded a total of 13,040 articles; 135 studies with 150 treatment conditions (N = 9562 participants) met the inclusion criteria (psychological interventions with children and/or adolescents with PTSD symptoms that report quantitative measures of symptom change). 

The mean effect sizes (ESs) for PTSD symptoms ranged from large to small, depending on the control condition. Cognitive behavioral therapy (CBT) yielded the highest ESs. Age and caretaker involvement were identified as moderators. CBT, especially when conducted in individual treatment with the inclusion of parents, is a highly effective treatment for trauma symptoms.

Psychological treatments need to be modified to address younger patients&#039; specific needs.
AD  - Gutermann, Jana. Department of Clinical Psychology and Psychotherapy, Goethe University, Varrentrappstr. 40-42, 60486, Frankfurt am Main, Germany. gutermann@psych.uni-frankfurt.de. Schreiber, Franziska. Department of Clinical Psychology and Psychotherapy, Goethe University, Varrentrappstr. 40-42, 60486, Frankfurt am Main, Germany. Matulis, Simone. Department of Clinical Psychology and Psychotherapy, Goethe University, Varrentrappstr. 40-42, 60486, Frankfurt am Main, Germany. Schwartzkopff, Laura. Department of Clinical Psychology and Psychotherapy, Goethe University, Varrentrappstr. 40-42, 60486, Frankfurt am Main, Germany. Deppe, Julia. Department of Clinical Psychology and Psychotherapy, Goethe University, Varrentrappstr. 40-42, 60486, Frankfurt am Main, Germany. Steil, Regina. Department of Clinical Psychology and Psychotherapy, Goethe University, Varrentrappstr. 40-42, 60486, Frankfurt am Main, Germany.
AN  - 27059619
AU  - Gutermann,
AU  - J.
AU  - Schreiber,
AU  - F.
AU  - Matulis,
AU  - S.
AU  - Schwartzkopff,
AU  - L.
AU  - Deppe,
AU  - J.
AU  - Steil,
AU  - R.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10567-016-0202-5
DP  - Ovid Technologies
J2  - Clin Child Fam Psychol Rev
L1  - internal-pdf://1460335712/Gutermann-2016-Psychological Treatments for Sy.pdf
LA  - English
M3  - Review
N1  - Gutermann, Jana Schreiber, Franziska Matulis, Simone Schwartzkopff, Laura Deppe, Julia Steil, Regina 10.1007/s10567-016-0202-5
PY  - 2016
SP  - 77-93
T2  - Clinical Child &amp; Family Psychology Review
TI  - Psychological Treatments for Symptoms of Posttraumatic Stress Disorder in Children, Adolescents, and Young Adults: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27059619http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27059619&amp;id=doi:10.1007%2Fs10567-016-0202-5&amp;issn=1096-4037&amp;isbn=&amp;volume=19&amp;issue=2&amp;spage=77&amp;pages=77-93&amp;date=2016&amp;title=Clinical+Child+%26+Family+Psychology+Review&amp;atitle=Psychological+Treatments+for+Symptoms+of+Posttraumatic+Stress+Disorder+in+Children%2C+Adolescents%2C+and+Young+Adults%3A+A+Meta-Analysis.&amp;aulast=Gutermann&amp;pid=%3Cauthor%3EGutermann+J%3C%2Fauthor%3E%3CAN%3E27059619%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s10567-016-0202-5
UR  - http://download.springer.com/static/pdf/793/art%253A10.1007%252Fs10567-016-0202-5.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10567-016-0202-5&amp;token2=exp=1489074341~acl=%2Fstatic%2Fpdf%2F793%2Fart%25253A10.1007%25252Fs10567-016-0202-5.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10567-016-0202-5*~hmac=9ac48b0a01f635cb693324bbb9bab087a99c3d813a4f4dce0b0d765c268fd724
VL  - 19
ER  -
TY  - JOUR
AB  - A meta-analysis on domestic violence interventions was conducted to determine overall effectiveness of mental health programs involving women and children in joint treatment.

These interventions were further analyzed to determine whether outcomes are differentially affected based on the outcome measure employed. To date, no meta-analyses have been published on domestic violence victim intervention efficacy. 

The 17 investigations that met study criteria yielded findings indicating that domestic violence interventions have a large effect size (d = .812), which decreases to a medium effect size when compared to control groups (d = .518). Effect sizes were assessed to determine whether treatment differed according to the focus of the outcome measure employed: (a) external stress (behavioral problems, aggression, or alcohol use); (b) psychological adjustment (depression, anxiety, or happiness); (c) self-concept (self-esteem, perceived competence, or internal locus of control); (d) social adjustment (popularity, loneliness, or cooperativeness); (e) family relations (mother-child relations, affection, or quality of interaction); and (f) maltreatment events (reoccurrence of violence, return to partner). 

Results reveal that domestic violence interventions across all outcome categories yield effects in the medium to large range for both internalized and externalized symptomatology. Implications for greater awareness and support for domestic violence treatment and programming are discussed. 

Copyright &copy; The Author(s) 2015.
AD  - Hackett, Shannon. The University of Oklahoma, Norman, OK, USA. McWhirter, Paula T. The University of Oklahoma, Norman, OK, USA paulamcwhirter@ou.edu. Lesher, Susan. The University of Oklahoma, Norman, OK, USA.
AN  - 25612799
AU  - Hackett,
AU  - S.
AU  - McWhirter,
AU  - P.
AU  - T.
AU  - Lesher,
AU  - S.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1524838014566720
DP  - Ovid Technologies
J2  - Trauma Violence Abuse Rev J
KW  - Adult
KW  - Child
KW  - *Cognitive Therapy
KW  - *Domestic Violence/px [Psychology]
KW  - Female
KW  - Humans
KW  - Intimate Partner Violence/px [Psychology]
KW  - Male
KW  - Mother-Child Relations
KW  - Social Support
KW  - Treatment Outcome
L1  - internal-pdf://0284292614/Hackett-2016-The Therapeutic Efficacy of Domes.pdf
LA  - English
M3  - Meta-Analysis
N1  - Hackett, Shannon McWhirter, Paula T Lesher, Susan 1524838014566720
PY  - 2016
SP  - 123-32
T2  - Trauma Violence &amp; Abuse
TI  - The Therapeutic Efficacy of Domestic Violence Victim Interventions
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25612799http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25612799&amp;id=doi:10.1177%2F1524838014566720&amp;issn=1524-8380&amp;isbn=&amp;volume=17&amp;issue=2&amp;spage=123&amp;pages=123-32&amp;date=2016&amp;title=Trauma+Violence+%26+Abuse&amp;atitle=The+Therapeutic+Efficacy+of+Domestic+Violence+Victim+Interventions.&amp;aulast=Hackett&amp;pid=%3Cauthor%3EHackett+S%3C%2Fauthor%3E%3CAN%3E25612799%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 17
ER  -
TY  - JOUR
AB  - **Objective: **
To use meta-analytic techniques to evaluating the effectiveness of parent-child interaction therapy (PCIT) at reducing future physical abuse among physically abusive families. 

**Methods: **
A systematic search identified six eligible studies. Outcomes of interest were physical abuse recurrence, child abuse potential, and parenting stress. 

**Results: **
Parents receiving PCIT had significantly fewer physical abuse recurrences and significantly greater reductions on the Parenting Stress Index than parents in comparison groups. Reductions in child abuse potential were nonsignificant, although 95% confidence intervals suggest clinically meaningful treatment effects. The studies examining physical abuse recurrence had a medium treatment effect (g = 0.52), while results from pooled effect size estimates for child abuse potential (g = 0.31) and parenting stress (g = 0.35) were small. 

**Conclusions: **
PCIT appears to be effective at reducing physical abuse recurrence and parenting stress for physically abusive families, with the largest treatment effects seen on long-term physical abuse recurrence. Applications to social work practice are discussed. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2016-06145-001
AU  - Kennedy,
AU  - S.
AU  - C.
AU  - Kim,
AU  - J.
AU  - S.
AU  - Tripodi,
AU  - S.
AU  - J.
AU  - Brown,
AU  - S.
AU  - M.
AU  - Gowdy,
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1049731514543024
L1  - internal-pdf://3389669174/Kennedy-2016-Does parent-child interaction the.pdf
PY  - 2016
SP  - 147-156
TI  - Does parent-child interaction therapy reduce future physical abuse? A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-06145-001
VL  - 26
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To review the efficacy and safety of aripiprazole (ARI) for Tourette&#039;s syndrome (TS). 

**METHODS: **
This review included randomized controlled trials (RCTs) of children and adolescents (6-18 years) with TS comparing ARI monotherapy with another monotherapies in relation to clinical improvement and adverse events. 

**RESULTS: **
Six RCTs with a total of 528 subjects (ARI treatment group: n = 253; control group: n = 275) met the inclusion criteria. These included two RCTs (n = 255) that compared ARI monotherapy with tiapride (TIA). Tic symptoms control assessed by Yale Global Tic Severity Scale (Standard Mean Difference (SMD)=-0.38 (Confidence Interval (CI)=-1.32 to 0.56); I(2) = 90%, P = 0.42) revealed no significant differences between the two groups. Extrapyramidal symptoms were significantly different when ARI (1.5%) was compared with haloperidol (HAL) (43.5%). No significant group differences were found in the rates of nausea/vomiting, dizziness, and dry mouth between ARI and TIA (RR = 0.57 to 1.00 (95%CI = 0.14-4.20); I(2) = 0% to 69%, P = 0.35 to 1.00). 

**CONCLUSION: **
This review found that ARI has similar efficacy to TIA and HAL for TS, while extrapyramidal symptoms were significantly less with ARI than with HAL. ARI can be considered as an alternative treatment option for TS. 

Copyright &copy; 2015 John Wiley &amp; Sons, Ltd.
AD  - Zheng, Wei. Beijing Anding Hospital, Capital Medical University, Beijing, China. Zheng, Wei. China National Clinical Research Center for Psychiatric Disorders, China. Li, Xian-Bin. Beijing Anding Hospital, Capital Medical University, Beijing, China. Li, Xian-Bin. China National Clinical Research Center for Psychiatric Disorders, China. Xiang, Ying-Qiang. Beijing Anding Hospital, Capital Medical University, Beijing, China. Xiang, Ying-Qiang. China National Clinical Research Center for Psychiatric Disorders, China. Zhong, Bao-Liang. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, SAR, China. Chiu, Helen F K. Department of Psychiatry, Chinese University of Hong Kong, Hong Kong, SAR, China. Ungvari, Gabor S. The University of Notre Dame Australia/Marian Centre, Perth, Australia. Ungvari, Gabor S. School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Australia. Ng, Chee H. Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia. Lok, Grace K I. Kiang Wu Nursing College of Macau, Macao, SRA, China. Xiang, Yu-Tao. Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao, SAR, China.
AN  - 26310194
AU  - Zheng,
AU  - W.
AU  - Li,
AU  - X.
AU  - B.
AU  - Xiang,
AU  - Y.
AU  - Q.
AU  - Zhong,
AU  - B.
AU  - L.
AU  - Chiu,
AU  - H.
AU  - F.
AU  - Ungvari,
AU  - G.
AU  - S.
AU  - Ng,
AU  - C.
AU  - H.
AU  - Lok,
AU  - G.
AU  - K.
AU  - Xiang,
AU  - Y.
AU  - T.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/hup.2498
DP  - Ovid Technologies
J2  - Hum
KW  - Adolescent
KW  - Antipsychotic Agents/ae [Adverse Effects]
KW  - *Antipsychotic Agents/tu [Therapeutic Use]
KW  - Aripiprazole/ae [Adverse Effects]
KW  - *Aripiprazole/tu [Therapeutic Use]
KW  - Basal Ganglia Diseases/ci [Chemically Induced]
KW  - Basal Ganglia Diseases/ep [Epidemiology]
KW  - Child
KW  - Haloperidol/ae [Adverse Effects]
KW  - Haloperidol/tu [Therapeutic Use]
KW  - Humans
KW  - Randomized Controlled Trials as Topic
KW  - Severity of Illness Index
KW  - *Tourette Syndrome/dt [Drug Therapy]
KW  - Tourette Syndrome/pp [Physiopathology]
KW  - Treatment Outcome
KW  - 0 (Antipsychotic Agents)
KW  - 82VFR53I78 (Aripiprazole)
KW  - J6292F8L3D (Haloperidol)
L1  - internal-pdf://2879126712/Zheng-2016-Aripiprazole for Tourette&#039;s syndrom.pdf
LA  - English
M3  - Comparative Study Meta-Analysis Review
N1  - Zheng, Wei Li, Xian-Bin Xiang, Ying-Qiang Zhong, Bao-Liang Chiu, Helen F K Ungvari, Gabor S Ng, Chee H Lok, Grace K I Xiang, Yu-Tao
PY  - 2016
SP  - 11-18
T2  - Human Psychopharmacology
TI  - Aripiprazole for Tourette&#039;s syndrome: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26310194http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26310194&amp;id=doi:10.1002%2Fhup.2498&amp;issn=0885-6222&amp;isbn=&amp;volume=31&amp;issue=1&amp;spage=11&amp;pages=11-8&amp;date=2016&amp;title=Human+Psychopharmacology&amp;atitle=Aripiprazole+for+Tourette%27s+syndrome%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Zheng&amp;pid=%3Cauthor%3EZheng+W%3C%2Fauthor%3E%3CAN%3E26310194%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1002/hup.2498/asset/hup2498.pdf?v=1&amp;t=j02h5pdx&amp;s=d99b6ca762d524089b467c6b965bff736cc954d4
VL  - 31
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
This study was conducted to perform an effect size analysis of psychosocial interventions for internet addiction and to identify the intervention moderators applied to school-aged children. 

**METHODS: **
For the meta-analysis, studies were included that were published in English or Korean until January 2015, without limitation in terms of the year. They were retrieved from 11 electronic databases and by manual searches according to predefined inclusion criteria. 

**RESULTS: **
A total of 37 studies were selected, which included 11 treatment conditions and covered a total of 1,490 participants. The effect size estimates showed that psychosocial interventions had a large effect for reducing internet addiction (standardized mean difference [SMD], -1.19; 95% confidence interval [CI], -1.52 to -0.87) and improving self-control (SMD, 0.29; 95% CI, 0.11 to 0.47) and self-esteem (mean difference, 3.58; 95% CI, 2.03 to 5.12). The moderator analyses reveals that group treatments, a selective approach, a long duration, a community setting, or higher school grade had a larger effect. 

**CONCLUSIONS: **
The findings of this review suggest that psychosocial intervention may be used to prevent Internet addiction in school-aged children, although further research should be conducted using a randomized controlled trial design or diverse age groups to provide evidence-based recommendations.
AD  - Yeun, Young Ran. Department of Nursing, Kangwon National University, Samcheok, Korea. Han, Suk Jung. Department of Nursing, Sahmyook University, Seoul, Korea.
AN  - 27525163
AU  - Yeun,
AU  - Y.
AU  - R.
AU  - Han,
AU  - S.
AU  - J.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4258/hir.2016.22.3.217
DP  - Ovid Technologies
J2  - Healthc
L1  - internal-pdf://4237097558/Yeun-2016-Effects of Psychosocial Intervention.pdf
LA  - English
N1  - Yeun, Young Ran Han, Suk Jung
PY  - 2016
SP  - 217-30
T2  - Healthcare Informatics Research
TI  - Effects of Psychosocial Interventions for School-aged Children&#039;s Internet Addiction, Self-control and Self-esteem: Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27525163http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27525163&amp;id=doi:10.4258%2Fhir.2016.22.3.217&amp;issn=2093-3681&amp;isbn=&amp;volume=22&amp;issue=3&amp;spage=217&amp;pages=217-30&amp;date=2016&amp;title=Healthcare+Informatics+Research&amp;atitle=Effects+of+Psychosocial+Interventions+for+School-aged+Children%27s+Internet+Addiction%2C+Self-control+and+Self-esteem%3A+Meta-Analysis.&amp;aulast=Yeun&amp;pid=%3Cauthor%3EYeun+YR%3C%2Fauthor%3E%3CAN%3E27525163%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981582/pdf/hir-22-217.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
Chronic irritability is a common presenting symptom in children and youth in both clinical settings (25%) and in the community (6%-8%). Treatment of irritability is relatively understudied. The purpose of this article is to synthesize evidence regarding the efficacy and safety of antidepressant medications for the treatment of irritability and related symptom dimensions in children and youth. 

**METHODS:** 
Systematic review of the literature was conducted to identify studies (including youth aged 6-18) that assessed the effectiveness of antidepressant medications for the treatment of irritability or related behavioral phenotypes, including aggression or symptoms of. Studies of youth with developmental disabilities or autism spectrum disorders were excluded. 

**RESULTS: **
We identified 99 studies (three randomized trials) assessing the effect of antidepressants in improving irritability, aggression, or oppositional symptoms as secondary outcomes. Only two studies specifically measured the outcome of irritability. Eight of the 11 studies reported significant effects on aggression, oppositionality, or irritability with antidepressant exposure, although effect sizes in all, but two of these, studies were less than 0.25. These effects were significantly reduced, but remained significant in seven of these studies after controlling for changes in comorbid depression scores with treatment. The other three studies reported no change, an increase in frequency of self-harm or aggressive behaviors or benefit in only a subsample of youth who tolerated the antidepressants after 1 year of follow-up. 

**CONCLUSION: **
Antidepressant medication exposure appears to have a small effect on irritability and related symptoms in youth. Heterogeneity in the study sample and absence of irritability being measured as a primary outcome across studies restrict the validity of the conclusions. Irritability is a debilitating outcome that needs specific attention in medication treatment studies.
AD  - Kim, Samuel. 1 Faculty of Health Sciences, McMaster University , Hamilton, Canada . Boylan, Khrista. 1 Faculty of Health Sciences, McMaster University , Hamilton, Canada . Boylan, Khrista. 2 Department of Psychiatry, McMaster University , Hamilton, Canada .
AN  - 27482998
AU  - Kim,
AU  - S,
AU  - Boylan,
AU  - K,
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1089/cap.2015.0127
DP  - Ovid Technologies
J2  - J Child Adolesc Psychopharmacol
L1  - internal-pdf://0219685977/Kim-2016-Effectiveness of Antidepressant Medic.pdf
LA  - English
N1  - Kim, Samuel Boylan, Khrista
PY  - 2016
SP  - 694-704
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Effectiveness of Antidepressant Medications for Symptoms of Irritability and Disruptive Behaviors in Children and Adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27482998http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27482998&amp;id=doi:10.1089%2Fcap.2015.0127&amp;issn=1044-5463&amp;isbn=&amp;volume=26&amp;issue=8&amp;spage=694&amp;pages=694-704&amp;date=2016&amp;title=Journal+of+Child+%26+Adolescent+Psychopharmacology&amp;atitle=Effectiveness+of+Antidepressant+Medications+for+Symptoms+of+Irritability+and+Disruptive+Behaviors+in+Children+and+Adolescents.&amp;aulast=Kim&amp;pid=%3Cauthor%3EKim+S%3C%2Fauthor%3E%3CAN%3E27482998%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://online.liebertpub.com/doi/abs/10.1089/cap.2015.0127
UR  - http://online.liebertpub.com/doi/pdfplus/10.1089/cap.2015.0127
VL  - 26
ER  -
TY  - JOUR
AB  - **Purpose: **
The aim of this study was to review the effect of school-based physical activity interventions on children&#039;s wellbeing. 

**Method: **
A systematic search of school-based physical activity studies was conducted using EBSCOhost PsycInfo, EBSCOhost Medline and Web of Science. Initially 995 studies were retrieved and, following the removal of duplicates, the titles and abstracts of 984 studies were screened. This screening identified 53 relevant studies from which 42 were excluded, resulting in 11 articles being reviewed. 

**Results: **
Three studies reported a positive increase in wellbeing; however, only one of those studies also significantly increased physical activity. It was apparent that the measurement of wellbeing and physical activity was inconsistent across studies, making conclusions difficult to draw. The wellbeing measures used neglected to account for the children&#039;s perspectives of wellbeing. 

**Conclusions: **
The effect of a physical activity intervention on increasing wellbeing appears to be more complex than originally believed. The complexity may in part be due to methodological issues and the choice of wellbeing and physical activity measurement. We recommend that future physical activity interventions include a measure of wellbeing developed from the child&#039;s perspective, and that future reviews narrow the search to only interventions that have had success at increasing physical activity before exploring effects on wellbeing. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Rafferty, Ruth: rafferty-r4@email.ulster.ac.uk Rafferty, Ruth, rafferty-r4@email.ulster.ac.uk Rafferty, Ruth: Sport and Exercise Science Research Institute, Ulster University, Newtownabbey, Northern Ireland Breslin, Gavin: Sport and Exercise Science Research Institute, Ulster University, Newtownabbey, Northern Ireland Brennan, Deirdre: Sport and Exercise Science Research Institute, Ulster University, Newtownabbey, Northern Ireland Hassan, David: Sport and Exercise Science Research Institute, Ulster University, Newtownabbey, Northern Ireland
AN  - 2016-37761-010
AU  - Rafferty,
AU  - R.
AU  - Breslin,
AU  - G.
AU  - Brennan,
AU  - D.
AU  - Hassan,
AU  - D.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/1750984X.2016.1164228
DP  - Ovid Technologies
KW  - Quality of life, intervention, health promotion, education, public health
KW  - *Childhood Development
KW  - *Physical Activity
KW  - *School Based Intervention
KW  - *Well Being
KW  - Curriculum &amp; Programs &amp; Teaching Methods [3530]
KW  - Human Childhood (birth-12 yrs) School Age (6-12 yrs)
L1  - internal-pdf://0332047978/A systematic review of school based physical a.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2016
SP  - 215-230
T2  - International Review of Sport and Exercise Psychology
TI  - A systematic review of school-based physical activity interventions on children&#039;s wellbeing
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-37761-010http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F1750984X.2016.1164228&amp;issn=1750-984X&amp;isbn=&amp;volume=9&amp;issue=1&amp;spage=215&amp;pages=215-230&amp;date=2016&amp;title=International+Review+of+Sport+and+Exercise+Psychology&amp;atitle=A+systematic+review+of+school-based+physical+activity+interventions+on+children%27s+wellbeing.&amp;aulast=Rafferty&amp;pid=%3Cauthor%3ERafferty%2C+Ruth%3C%2Fauthor%3E%3CAN%3E2016-37761-010%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 9
ER  -
TY  - JOUR
AB  - **Objective: **
Aggression Replacement Training (ART) is a multimodal program aiming at replacing antisocial behaviors by actively teaching desirable behaviors. The program is frequently used and has been provided within a wide variety of settings, but its effectiveness in its own right has not been addressed in previous reviews. This systematic review examines the effect of ART on antisocial behavior in young people and adults. 

**Methods: **
Published and unpublished literature was searched to identify randomized and non-randomized studies comparing ART for adults and youth with usual care, other interventions, or no intervention. Primary outcomes included recidivism in antisocial behavior, while secondary outcomes were related to social skills, anger management and moral reasoning. 

**Findings: **
This review identified 16 studies with considerable clinical and methodological diversity. The methodological quality and the post-intervention follow-up of the studies were limited. Almost half of the studies were conducted by researchers who have vested interests in the intervention. 

**Conclusions: **
There is an insufficient evidence-base to substantiate the hypothesis that ART has a positive impact on recidivism, self-control, social skills or moral development in adolescents and adults. Further research is warranted by independent investigators exploring the effects of ART on clearly-defined target groups using high standard evaluation designs. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Brannstrom, Lars: lars.brannstrom@socarb.su.se Brannstrom, Lars: Department of Social Work, Stockholm University, Stockholm, Sweden, SE-10691, lars.brannstrom@socarb.su.se Brannstrom, Lars: Department of Social Work, Stockholm University, Stockholm, Sweden Kaunitz, Catrine: National Board of Institutional Care, Sweden Andershed, Anna-Karin: School of Law, Psychology and Social Work, Orebro University, Orebro, Sweden South, Sandra: National Board of Health and Welfare, Sweden Smedslund, Geir: Knowledge Centre for the Health Services, Norway
AN  - 2016-20082-004
AU  - Brannstrom,
AU  - L.
AU  - Kaunitz,
AU  - C.
AU  - Andershed,
AU  - A.
AU  - K.
AU  - South,
AU  - S.
AU  - Smedslund,
AU  - G.
DA  - Mar-Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.avb.2016.02.006
DP  - Ovid Technologies
KW  - Intervention, Effectiveness, Aggression Replacement Training, ART, Delinquency
KW  - *Aggressive Behavior
KW  - *Antisocial Behavior
KW  - *Juvenile Delinquency
KW  - *Training
KW  - *Treatment Effectiveness Evaluation
KW  - Intervention
KW  - Behavior Disorders &amp; Antisocial Behavior [3230]
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human Male Female Childhood (birth-12 yrs) Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older)
L1  - internal-pdf://4256275939/Brannstrom-2016-Aggression replacement trainin.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2016
SP  - 30-41
T2  - Aggression and Violent Behavior
TI  - Aggression replacement training (ART) for reducing antisocial behavior in adolescents and adults: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-20082-004http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.avb.2016.02.006&amp;issn=1359-1789&amp;isbn=&amp;volume=27&amp;issue=&amp;spage=30&amp;pages=30-41&amp;date=2016&amp;title=Aggression+and+Violent+Behavior&amp;atitle=Aggression+replacement+training+%28ART%29+for+reducing+antisocial+behavior+in+adolescents+and+adults%3A+A+systematic+review.&amp;aulast=Brannstrom&amp;pid=%3Cauthor%3EBrannstrom%2C+Lars%3C%2Fauthor%3E%3CAN%3E2016-20082-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S1359178916300064/1-s2.0-S1359178916300064-main.pdf?_tid=122f8c2c-04c3-11e7-a456-00000aacb360&amp;acdnat=1489062332_20fb68133b3a16584d2ebc91d9436afb
VL  - 27
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Suicide is a significant public health issue, and is especially concerning in adolescents and young adults, who are over-represented both in attempts and completed suicide. Emerging technologies represent a promising new approach to deliver suicide prevention interventions to these populations. The current systematic review aims to identify online and mobile psychosocial suicide prevention interventions for young people, and evaluate the effectiveness of these interventions. 

**METHOD: **
PsycINFO, Medline, Embase and The Cochrane Library were electronically searched for all articles published between January, 2000 and May, 2015. Peer-reviewed journal articles reporting on interventions for young people aged 12-25 years with suicidality as a primary outcome were eligible for inclusion. No exclusions were placed on study design. 

**RESULTS:**
One study met inclusion criteria, and found significant reductions in the primary outcome of suicidal ideation, as well as depression and hopelessness. Two relevant protocol papers of studies currently underway were also identified. 

**CONCLUSIONS: **
There is a paucity of current evidence for online and mobile interventions for suicide prevention in youth. More high quality empirical evidence is required to determine the effectiveness of these novel approaches to improving suicide outcomes in young people.
AD  - Perry, Yael. Black Dog Institute, University of New South Wales, Sydney, NSW, Australia. Werner-Seidler, Aliza. Black Dog Institute, University of New South Wales, Sydney, NSW, Australia. Calear, Alison L. National Institute for Mental Health Research, The Australian National University, Canberra, ACT, Australia. Christensen, Helen. Black Dog Institute, University of New South Wales, Sydney, NSW, Australia.
AN  - 27274742
AU  - Perry,
AU  - Y.
AU  - Werner-Seidler,
AU  - A.
AU  - Calear,
AU  - A.
AU  - L.
AU  - Christensen,
AU  - H.
DA  - Spring
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879946/
DP  - Ovid Technologies
J2  - J Can Acad Child Adolesc Psychiatry
L1  - internal-pdf://0491692252/Perry-2016-Web-Based and Mobile Suicide Preven.pdf
LA  - English
N1  - Perry, Yael Werner-Seidler, Aliza Calear, Alison L Christensen, Helen
PY  - 2016
SP  - 73-9
T2  - Journal of the Canadian Academy of Child &amp; Adolescent Psychiatry = Journal de l.Acade.mie canadienne de psychiatrie de l.enfant et de l.adolescent
TI  - Web-Based and Mobile Suicide Prevention Interventions for Young People: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27274742http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27274742&amp;id=doi:&amp;issn=1719-8429&amp;isbn=&amp;volume=25&amp;issue=2&amp;spage=73&amp;pages=73-9&amp;date=2016&amp;title=Journal+of+the+Canadian+Academy+of+Child+%26+Adolescent+Psychiatry+%3D+Journal+de+l.Acade.mie+canadienne+de+psychiatrie+de+l.enfant+et+de+l.adolescent&amp;atitle=Web-Based+and+Mobile+Suicide+Prevention+Interventions+for+Young+People%3A+A+Systematic+Review.&amp;aulast=Perry&amp;pid=%3Cauthor%3EPerry+Y%3C%2Fauthor%3E%3CAN%3E27274742%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879946/pdf/ccap25_p0073.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - The purpose of this review was to critically examine and summarize the impact of school-based interventions designed to decrease challenging behaviors in young children with Autism Spectrum Disorder (ASD). 

Reviewed studies employed a single-case experimental design, targeted challenging behaviors, included children 3-8 years old with ASD, and took place in school settings. 

Interventions were categorized as antecedent-based, function-based, reinforcement, instructional, or multicomponent. In addition to analyzing articles descriptively, effect size estimates were calculated using the Non-overlap of All Pairs and Tau-U methods. A total of 26 studies including 44 children were reviewed. 

Individual effect size estimates ranged from weak to strong, but on average, the reviewed interventions were effective in decreasing the target behaviors exhibited by the participants. 

Findings suggest that interventions implemented in school settings can effectively decrease challenging behaviors exhibited by young children with ASD. Directions for future research and practice are also discussed.
AD  - [Martinez, Jose R.; Werch, Brittany L.; Conroy, Maureen A.] Univ Florida, Gainesville, FL 32611 USA. Martinez, JR (reprint author), Univ Florida, Coll Educ, 1345 Norman Hall 618,SW 12th St, Gainesville, FL 32611 USA. j.martinez36@ufl.edu
AN  - WOS:000381539300004
AU  - Martinez,
AU  - J.
AU  - R.
AU  - Werch,
AU  - B.
AU  - L.
AU  - Conroy,
AU  - M.
AU  - A.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Har ikke DOI
J2  - Educ. Train. Autism Dev. Disabil.
KW  - decreasing disruptive behaviors
KW  - single-case research
KW  - vocal stereotypy
KW  - social stories
KW  - students
KW  - schedules
KW  - reinforcement
KW  - classroom
KW  - play
KW  - Education &amp; Educational Research
KW  - Rehabilitation
L1  - internal-pdf://3275844531/out(13).pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DT5RC Times Cited: 0 Cited Reference Count: 50 Martinez, Jose R. Werch, Brittany L. Conroy, Maureen A. 0 15 Council exceptional children Arlington
PY  - 2016
SP  - 265-280
T2  - Education and Training in Autism and Developmental Disabilities
TI  - School-Based Interventions Targeting Challenging Behaviors Exhibited by Young Children with Autism Spectrum Disorder: A Systematic Literature Review
UR  - &lt;Go to ISI&gt;://WOS:000381539300004
VL  - 51
ER  -
TY  - JOUR
AB  - Bakgrunn
Denne artikkelen er en kunnskapsoppsummering for effektene av tiltaket Grønne tanker- glade barn. Artikkelen er en revisjon av en tidligere beskrivelse av samme tiltaket i Ungsinn (Eng &amp; Ulvund, 2015), men videreutviklet i henhold til Ungsinn sine nye prosedyrer og kriterier. Grønne tanker &ndash; glade barn er en materiellpakke som kan brukes i barnehagen for å stimulere barns tanke- og følelsesbevissthet. Det skal hjelpe barna med å forstå egne og andres følelsesreaksjoner, å bli bedre i stand til å regulere egne følelser og gjennom dette også bidra til et godt psykososialt miljø. Tiltaket kan brukes universelt med mål om å styrke psykosial utvikling for alle barn. Samtidig legges det opp til at en kan bruke materiellet i en styrket innsats for barn som har større utfordringer enn andre med engstelse, sinne eller tristhet. Organisasjonen Voksne for Barn er ansvarlig for implementering av tiltaket i Norge, og de tilbyr også opplæring. Formålet med denne artikkelen er å undersøke om Grønne tanker &ndash; glade barn kan antas å være virksomt benyttet i vanlig praksis i Norge.

Metode
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS og SweMed samt informasjon gitt fra tiltakseier i Norge.

Resultater
Resultatene omfatter en oppsummering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Tiltakets bakgrunn, innhold og metoder er godt beskrevet i tiltakets materiell og gjennom to fagartikler. Tiltaket har også god teoretisk og empirisk forankring gjennom kognitiv atferdsterapi, men det foreligger ingen studier der tiltakets effekt er undersøkt. Tiltaket er fritt tilgjengelig, og utover en kort opplæring tilbys det lite implementeringsstøtte. Det finnes heller ikke systemer som sikrer at tiltaket implementeres med god kvalitet. Det er grunn til å tro at tiltaket utøves svært ulikt i forskjellige barnehager, noe som sannsynligvis har betydning for effektene av tiltaket.

Konklusjon
Grønne tanker &ndash; glade barn er et tilfredsstillende beskrevet tiltak som åpenbart treffer et behov i folkehelsearbeidet, og som er tilpasset barnehagenes rammeplan. Studier på tiltakets effekter og hvordan tiltaket best utøves for å oppnå eventuelle effekter, er nødvendig for å vite om tiltaket er virksomt.  Gjennomføring av en god effektstudie vil imidlertid forutsette en bedre presisering av tiltakets konkrete målsetninger. En god teoretisk forankring styrker sannsynligheten for at tiltaket kan fremme god psykisk helse og redusere vansker for barn i tidlig alder.

Grønne tanker &ndash; glade barn klassifiseres på evidensnivå 2 &ndash; Teoretisk begrunnede tiltak.
AU  - Eng,
AU  - H.,
AU  - Ulvund,
AU  - S.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2016
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Grønne tanker &ndash; glade barn (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/kunnskapsoppsummering-og-klassifisering-av-tiltaket-gronne-tanker-glade-barn-2-utg/
VL  - 1
ER  -
TY  - GEN
AB  - **Background:** 
Controversy exists over whether longchain polyunsaturated fatty acids (LCPUFA) are essential nutrients for preterm infants because they may not be able to synthesise sufficient amounts of LCPUFA to meet the needs of the developing brain and retina.

**Objectives:** 
To assess whether supplementation of formula milk with LCPUFA is safe and of benefit to preterm infants. The main areas of interest were the effects of supplementation on the visual function, development and growth of preterm infants.

**Search methods:** 
Trials were identified by searching the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 2) in the Cochrane Library (searched 28 February 2016), MEDLINE Ovid (1966 to 28 February 2016), Embase Ovid (1980 to 28 February 2016), CINAHL EBSCO (Cumulative Index to Nursing and Allied Health Literature; 1980 to 28 February 2016), MEDLINE In Process &amp; Other Non-indexed Citations (1966 to 28 February 2016) and by checking reference lists of articles and conference proceedings. We also searched ClinicalTrials.gov (13 April 2016). No language restrictions were applied.

**Selection criteria:** 
All randomised trials evaluating the effect of LCPUFA-supplemented formula in enterally-fed preterm infants (compared with standard formula) on visual development, neurodevelopment and physical growth. Trials reporting only biochemical outcomes were not included.

**Data collection and analysis:** 
All authors assessed eligibility and trial quality, two authors extracted data separately. Study authors were contacted for additional information.

**Main results:** 
Seventeen trials involving 2260 preterm infants were included in the review. The risk of bias varied across the included trials with 10 studies having low risk of bias in a majority of the domains. The median gestational age (GA) in the included trials was 30 weeks and median birth weight (BW) was 1300 g. The median concentration of docosahexaenoic acid (DHA) was 0.33% (range: 0.15% to 1%) and arachidonic acid (AA) 0.37% (range: 0.02% to 0.84%). Visual acuity Visual acuity over the first year was measured by Teller or Lea acuity cards in eight studies, by visual evoked potential (VEP) in six studies and by electroretinogram (ERG) in two studies. Most studies found no significant differences in visual acuity between supplemented and control infants. The form of data presentation and the varying assessment methods precluded the use of meta-analysis. A GRADE analysis for this outcome indicated that the overall quality of evidence was low. Neurodevelopment Three out of seven studies reported some benefit of LCPUFA on neurodevelopment at different postnatal ages. Meta-analysis of four studies evaluating Bayley Scales of Infant Development at 12 months (N = 364) showed no significant effect of supplementation (Mental Development Index (MDI): MD 0.96, 95% CI ?1.42 to 3.34; P = 0.43; I&sup2; = 71% - Psychomotor DeveIopment Index (PDI): MD 0.23, 95% CI ?2.77 to 3.22; P = 0.88; I&sup2; = 81%). Furthermore, three studies at 18 months (N = 494) also revealed no significant effect of LCPUFA on neurodevelopment (MDI: MD 2.40, 95% CI ?0.33 to 5.12; P = 0.08; I&sup2; = 0% - PDI: MD 0.74, 95% CI ?1.90 to 3.37; P = 0.58; I&sup2; = 54%). A GRADE analysis for these outcomes indicated that the overall quality of evidence was low. Physical growth Four out of 15 studies reported benefits of LCPUFA on growth of supplemented infants at different postmenstrual ages (PMAs), whereas two trials suggested that LCPUFA-supplemented infants grow less well. One trial reported mild reductions in length and weight z scores at 18 months. Meta-analysis of five studies (N = 297) showed increased weight and length at two months post-term in supplemented infants (Weight: MD 0.21, 95% CI 0.08 to 0.33; P = 0.0010; I&sup2; = 69% - Length: MD 0.47, 95% CI 0.00 to 0.94; P = 0.05; I&sup2; = 0%). Meta-analysis of four studies at a corrected age of 12 months (N = 271) showed no significant effect of supplementation on growth outcomes (Weight: MD ?0.10, 95% CI ?0.31 to 0.12; P = 0.34; I&sup2; = 65% - Length: MD 0.25; 95% CI ?0.33 to 0.8 ; P = 0.40; I&sup2; = 71% - Head circumference: MD ?0.15, 95% CI ?0.53 to 0.23; P = 0.45; I&sup2; = 0%). No significant effect of LCPUFA on weight, length or head circumference was observed on meta-analysis of two studies (n = 396 infants) at 18 months (Weight: MD ?0.14, 95% CI ?0.39 to 0.10; P = 0.26; I&sup2; = 66% - Length: MD ?0.28, 95% CI ?0.91 to 0.35; P = 0.38; I&sup2; = 90% - Head circumference: MD ?0.18, 95% CI ?0.53 to 0.18; P = 0.32; I&sup2; = 0%). A GRADE analysis for this outcome indicated that the overall quality of evidence was low.

**Authors&#039; conclusions:** 
Infants enrolled in the trials were relatively mature and healthy preterm infants. Assessment schedule and methodology, dose and source of supplementation and fatty acid composition of the control formula varied between trials. On pooling of results, no clear long-term benefits or harms were demonstrated for preterm infants receiving LCPUFA-supplemented formula.
AN  - CD000375
AU  - Moon,
AU  - K.
AU  - Rao,
AU  - S.
AU  - C.
AU  - Schulzke,
AU  - S.
AU  - M.
AU  - Patole,
AU  - S.
AU  - K.
AU  - Simmer,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd000375.pub5
KW  - Dietary Supplements
KW  - Arachidonic Acid [administration &amp; dosage]
KW  - Docosahexaenoic Acids [administration &amp; dosage]
KW  - Fatty Acids, Unsaturated [administration &amp; dosage]
KW  - Infant Formula [chemistry]
KW  - Infant Nutritional Physiological Phenomena
KW  - Infant, Premature [growth &amp; development]
KW  - Intelligence [physiology]
KW  - Randomized Controlled Trials as Topic
KW  - Vision, Ocular [physiology]
KW  - Visual Acuity [physiology]
KW  - Humans[checkword]
KW  - Infant, Newborn[checkword]
L1  - internal-pdf://2100231759/moon.pdf
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Longchain polyunsaturated fatty acid supplementation in preterm infants
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000375.pub5/abstract
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000375.pub5/abstract?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+7th+Oct+from+03.00+EDT+%2F+08%3A00+BST+%2F+12%3A30+IST+%2F+15.00+SGT+to+08.00+EDT+%2F+13.00+BST+%2F+17%3A30+IST+%2F+20.00+SGT+and+Sunday+8th+Oct+from+03.00+EDT+%2F+08%3A00+BST+%2F+12%3A30+IST+%2F+15.00+SGT+to+06.00+EDT+%2F+11.00+BST+%2F+15%3A30+IST+%2F+18.00+SGT+for+essential+maintenance.+Apologies+for+the+inconvenience+caused+
UR  - .
ER  -
TY  - JOUR
AB  - Intervention by community health workers (CHWs) is believed to prevent repeated childbearing among teenagers. This review investigated the effectiveness of CHWs in reducing repeated pregnancies and births among adolescents aged &lt;20 years, 2 years after the delivery of their first child. 

Through electronic database and hand searching, experimental and/or observational studies were screened with their results undergoing systematic review and meta-analyses. Subgroup analyses were performed to further assess how study characteristics affected the pooled estimates and heterogeneity. A total of 11 eligible articles, from January 1980 to May 2015, were included. 

Seven studies evaluated repeated births and eight measured repeated pregnancies. Studies showed relevant disparities in terms of selected methodological aspects and program characteristics. Although most studies (n = 9) were either of &quot;strong&quot; or of &quot;moderate&quot; quality, only two of five finding a significant reduction exhibited a high level of quality as the other three failed to adjust results for confounders. 

Random effects modeling revealed an overall 30% decrease in repeated adolescent births (odds ratio = .70, confidence interval = .49-.99) among CHW-visited areas relative to nonvisited sites. On the other hand, no significant association was detected in terms of repeated pregnancies (odds ratio = .96, confidence interval = .70-1.28). 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Maravilla, Joemer Calderon: joemer.maravilla@uq.net.au Maravilla, Joemer Calderon: School of Public Health, University of Queensland, 4th floor Public Health Building, Herston Rd, Herston, Brisbane, QLD, Australia, 4006, joemer.maravilla@uq.net.au Maravilla, Joemer Calderon: School of Public Health, University of Queensland, Brisbane, QLD, Australia Betts, Kim S.: School of Public Health, University of Queensland, Brisbane, QLD, Australia Abajobir, Amanuel Alemu: School of Public Health, University of Queensland, Brisbane, QLD, Australia Couto e Cruz, Camila: School of Public Health, University of Queensland, Brisbane, QLD, Australia Alati, Rosa: School of Public Health, University of Queensland, Brisbane, QLD, Australia
AN  - 2016-37408-001
AU  - Maravilla,
AU  - J.
AU  - C.
AU  - Betts,
AU  - K.
AU  - S.
AU  - Abajobir,
AU  - A.
AU  - A.
AU  - Couto
AU  - e
AU  - Cruz,
AU  - C.
AU  - Alati,
AU  - R.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jadohealth.2016.05.011
DP  - Ovid Technologies
KW  - community health worker, repeated teenage pregnancy, repeated teenage births, teenage pregnancy, adolescent, meta-analysis
KW  - *Adolescent Pregnancy
KW  - *Prevention
KW  - *Health Personnel
KW  - *Community Health
KW  - Birth
KW  - Promotion &amp; Maintenance of Health &amp; Wellness [3365]
KW  - Human Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older)
L1  - internal-pdf://0544565804/Maravilla-2016-The role of community health wo.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2016
SP  - 378-390
T2  - Journal of Adolescent Health
TI  - The role of community health workers in preventing adolescent repeat pregnancies and births
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-37408-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jadohealth.2016.05.011&amp;issn=1054-139X&amp;isbn=&amp;volume=59&amp;issue=4&amp;spage=378&amp;pages=378-390&amp;date=2016&amp;title=Journal+of+Adolescent+Health&amp;atitle=The+role+of+community+health+workers+in+preventing+adolescent+repeat+pregnancies+and+births.&amp;aulast=Maravilla&amp;pid=%3Cauthor%3EMaravilla%2C+Joemer+Calderon%3C%2Fauthor%3E%3CAN%3E2016-37408-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S1054139X16300830/1-s2.0-S1054139X16300830-main.pdf?_tid=e45399ca-04cb-11e7-b3c8-00000aacb360&amp;acdnat=1489066121_9cf110f0c429a4a33f366cff4b23f6e6
VL  - 59
ER  -
TY  - JOUR
AB  - Attention-deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed mental health disorders and is associated with higher incidence of comorbid oppositional or conduct, mood, anxiety, pervasive developmental, and substance-use disorders. 

Comorbid mental health conditions may alter the presence of symptoms and treatment of ADHD. Atomoxetine (ATX), a nonstimulant medication for the treatment of ADHD, may be prescribed for individuals with ADHD and comorbid conditions despite some risk for certain undesirable side effects and lower effectiveness for the treatment of ADHD than stimulants. In this paper, we review studies utilizing randomized, placebo-controlled trials (RCTs) as well as within-subject designs to determine the effectiveness of ATX in the treatment of children and adults with ADHD and comorbid conditions. 

The current review uses an expanded methodology beyond systematic review of randomized controlled trials in order to improve generalizability of results to real-world practice. A total of 24 articles published from 2007 to 2015 were reviewed, including 14 RCTs: n = 1348 ATX, and n = 832 placebo. The majority of studies show that ATX is effective in the treatment of ADHD symptoms for individuals with ADHD and comorbid disorders. Cohen&#039;s d effect sizes (ES) for improvement in ADHD symptoms and behaviors range from 0.47 to 2.21. 

The effectiveness of ATX to improve symptoms specific to comorbidity varied by type but appeared to be most effective for diminishing the presence of symptoms for those with comorbid anxiety, ES range of 0.40 to 1.51, and oppositional defiant disorder, ES range of 0.52 to 1.10. There are mixed or limited results for individuals with ADHD and comorbid substance-use disorders, autism spectrum disorders, dyslexia or reading disorder, depression, bipolar disorder, and Tourette syndrome. 

Results from this review suggest that ATX is effective in the treatment of some youth and adults with ADHD and comorbid disorders, and may be a treatment option in these patients.
AD  - Hutchison, Shari L. Community Care Behavioral Health, UPMC Insurance Services Division, 339 Sixth Avenue, Suite 1300, Pittsburgh, PA 15222, USA. Ghuman, Jaswinder K. Community Care Behavioral Health, UPMC Insurance Services Division, Pittsburgh, PA, USA. Ghuman, Harinder S. Allegheny Behavioral Health, Sewickley, PA, USA. Karpov, Irina. Community Care Behavioral Health, UPMC Insurance Services Division, Pittsburgh, PA, USA. Schuster, James M. Community Care Behavioral Health, UPMC Insurance Services Division, Pittsburgh, PA, USA.
AN  - 27721971
AU  - Hutchison,
AU  - S.
AU  - L.
AU  - Ghuman,
AU  - J.
AU  - K.
AU  - Ghuman,
AU  - H.
AU  - S.
AU  - Karpov,
AU  - I.
AU  - Schuster,
AU  - J.
AU  - M.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/ 2045125316647686
DP  - Ovid Technologies
J2  - Ther
L1  - internal-pdf://2054362000/Hutchison-2016-Efficacy of atomoxetine in the.pdf
LA  - English
M3  - Review
N1  - Hutchison, Shari L Ghuman, Jaswinder K Ghuman, Harinder S Karpov, Irina Schuster, James M 10.1177_2045125316647686
PY  - 2016
SP  - 317-334
T2  - Therapeutic Advances in Psychopharmacology
TI  - Efficacy of atomoxetine in the treatment of attention-deficit hyperactivity disorder in patients with common comorbidities in children, adolescents and adults: a review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27721971http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27721971&amp;id=doi:10.1177%2F2045125316647686&amp;issn=2045-1253&amp;isbn=&amp;volume=6&amp;issue=5&amp;spage=317&amp;pages=317-334&amp;date=2016&amp;title=Therapeutic+Advances+in+Psychopharmacology&amp;atitle=Efficacy+of+atomoxetine+in+the+treatment+of+attention-deficit+hyperactivity+disorder+in+patients+with+common+comorbidities+in+children%2C+adolescents+and+adults%3A+a+review.&amp;aulast=Hutchison&amp;pid=%3Cauthor%3EHutchison+SL%3C%2Fauthor%3E%3CAN%3E27721971%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036135/pdf/10.1177_2045125316647686.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **Background: **
Child maltreatment is a substantial social problem that affects large numbers of children and young people in the UK, resulting in a range of significant short- and long-term psychosocial problems. 

**Objectives: **
To synthesise evidence of the effectiveness, cost-effectiveness and acceptability of interventions addressing the adverse consequences of child maltreatment. 

**Study design:** 
For effectiveness, we included any controlled study. Other study designs were considered for economic decision modelling. For acceptability, we included any study that asked participants for their views. 

**Participants: **
Children and young people up to 24 years 11 months, who had experienced maltreatment before the age of 17 years 11 months. Interventions: Any psychosocial intervention provided in any setting aiming to address the consequences of maltreatment. 

**Main outcome measures: **
Psychological distress [particularly post-traumatic stress disorder (PTSD), depression and anxiety, and self-harm], behaviour, social functioning, quality of life and acceptability. 

**Methods: **
Young Persons and Professional Advisory Groups guided the project, which was conducted in accordance with Cochrane Collaboration and NHS Centre for Reviews and Dissemination guidance. Departures from the published protocol were recorded and explained. Meta-analyses and cost-effectiveness analyses of available data were undertaken where possible. 

**Results: **
We identified 198 effectiveness studies (including 62 randomised trials); six economic evaluations (five using trial data and one decision-analytic model); and 73 studies investigating treatment acceptability. Pooled data on cognitive-behavioural therapy (CBT) for sexual abuse suggested post-treatment reductions in PTSD [standardised mean difference (SMD) -0.44 (95% CI -4.43 to -1.53)], depression [mean difference -2.83 (95% CI -4.53 to -1.13)] and anxiety [SMD -0.23 (95% CI -0.03 to -0.42)]. No differences were observed for post-treatment sexualised behaviour, externalising behaviour, behaviour management skills of parents, or parental support to the child. Findings from attachment-focused interventions suggested improvements in secure attachment [odds ratio 0.14 (95% CI 0.03 to 0.70)] and reductions in disorganised behaviour [SMD 0.23 (95% CI 0.13 to 0.42)], but no differences in avoidant attachment or externalising behaviour. Few studies addressed the role of caregivers, or the impact of the therapist-child relationship. Economic evaluations suffered methodological limitations and provided conflicting results. As a result, decision-analytic modelling was not possible, but cost-effectiveness analysis using effectiveness data from meta-analyses was undertaken for the most promising intervention: CBT for sexual abuse. Analyses of the cost-effectiveness of CBT were limited by the lack of cost data beyond the cost of CBT itself. 

**Conclusions: **
It is not possible to draw firm conclusions about which interventions are effective for children with different maltreatment profiles, which are of no benefit or are harmful, and which factors encourage people to seek therapy, accept the offer of therapy and actively engage with therapy. Little is known about the cost-effectiveness of alternative interventions. 

**Limitations:**
Studies were largely conducted outside the UK. The heterogeneity of outcomes and measures seriously impacted on the ability to conduct meta-analyses. 

**Future work: **
Studies are needed that assess the effectiveness of interventions within a UK context, which address the wider effects of maltreatment, as well as specific clinical outcomes.
AD  - [Macdonald, Geraldine; Livingstone, Nuala; Hanratty, Jennifer; McCartan, Claire; Bosqui, Tania] Queens Univ Belfast, Inst Child Care Res, Sch Sociol Social Policy &amp; Social Work, Belfast, Antrim, North Ireland. [Macdonald, Geraldine] Univ Bristol, Sch Policy Studies, Bristol, Avon, England. [Cotmore, Richard] NSPCC, Evaluat Dept, London, England. [Cary, Maria; Byford, Sarah] Kings Coll London, Kings Hlth Econ, London, England. [Glaser, Danya] UCL, London, England. [Glaser, Danya] Great Ormond St Hosp Sick Children, London, England. [Welton, Nicky J.; Audrey, Suzanne; Churchill, Rachel] Univ Bristol, Sch Social &amp; Community Med, Bristol, Avon, England. [Bowes, Lucy] Univ Oxford, Dept Expt Psychol, Oxford, England. [Mezey, Gill] St Georges Univ London, Populat Hlth Sci &amp; Educ, London, England. [Riches, Wendy] Riches &amp; Ullman Ltd, Liabil Partnership, London, England. Macdonald, G (reprint author), Queens Univ Belfast, Inst Child Care Res, Sch Sociol Social Policy &amp; Social Work, Belfast, Antrim, North Ireland.; Macdonald, G (reprint author), Univ Bristol, Sch Policy Studies, Bristol, Avon, England. Geraldine.Macdonald@bristol.ac.uk
AN  - WOS:000385418500001
AU  - Macdonald,
AU  - G.
AU  - Livingstone,
AU  - N.
AU  - Hanratty,
AU  - J.
AU  - McCartan,
AU  - C.
AU  - Cotmore,
AU  - R.
AU  - Cary,
AU  - M.
AU  - Glaser,
AU  - D.
AU  - Byford,
AU  - S.
AU  - Welton,
AU  - N.
AU  - J.
AU  - Bosqui,
AU  - T.
AU  - Bowes,
AU  - L.
AU  - Audrey,
AU  - S.
AU  - Mezey,
AU  - G.
AU  - Fisher,
AU  - H.
AU  - L.
AU  - Riches,
AU  - W.
AU  - Churchill,
AU  - R.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - DOI 10.3310/hta20690
J2  - Health Technol. Assess.
KW  - cognitive-behavioral therapy
KW  - sexually-abused girls
KW  - posttraumatic-stress-disorder
KW  - randomized controlled-trial
KW  - treatment
KW  - foster-care
KW  - addiction severity index
KW  - general health questionnaire
KW  - community-based intervention
KW  - elementary-school-children
KW  - home-visiting
KW  - intervention
KW  - Health Care Sciences &amp; Services
L1  - internal-pdf://4039072802/3003450.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: DY8YM Times Cited: 0 Cited Reference Count: 803 Macdonald, Geraldine Livingstone, Nuala Hanratty, Jennifer McCartan, Claire Cotmore, Richard Cary, Maria Glaser, Danya Byford, Sarah Welton, Nicky J. Bosqui, Tania Bowes, Lucy Audrey, Suzanne Mezey, Gill Fisher, Helen L. Riches, Wendy Churchill, Rachel Byford, Sarah/D-1699-2010 Byford, Sarah/0000-0001-7084-1495 National Institute for Health Research Health Technology Assessment programme The National Institute for Health Research Health Technology Assessment programme. 0 14 Nihr journals library Southampton 2046-4924
PY  - 2016
SP  - 1-+
T2  - Health Technology Assessment
TI  - The effectiveness, acceptability and cost-effectiveness of psychosocial interventions for maltreated children and adolescents: an evidence synthesis
UR  - &lt;Go to ISI&gt;://WOS:000385418500001
VL  - 20
ER  -
TY  - JOUR
AB  - This review evaluates the efficacy of using physical exercise interventions on improving cognitive functions in individuals with autism spectrum disorder (ASD) and/or attention deficit hyperactivity disorder (ADHD). 

This review includes a meta-analysis based on a random-effects model of data reported in 22 studies with 579 participants aged 3-25 year old. The results revealed an overall small to medium effect of exercise on cognition, supporting the efficacy of exercise interventions in enhancing certain aspects of cognitive performance in individuals with ASD and/or ADHD. 

Specifically, similar to the general population literature, the cognitive benefits of exercise are not consistent across all aspects of cognitive functions (i.e., some areas are not improved). The clinical significance of the reported effect sizes is also considered. 

Copyright &copy; 2016, The Author(s).
AD  - (Tan, Pooley, Speelman) School of Arts and Humanities, Edith Cowan University, 270 Joondalup Drive, Joondalup, WA 6027, Australia B.W.Z. Tan, School of Arts and Humanities, Edith Cowan University, 270 Joondalup Drive, Joondalup, WA 6027, Australia. E-mail: b.tan@ecu.edu.au
AN  - 611223375
AU  - Tan,
AU  - B.
AU  - W.
AU  - Z.
AU  - Pooley,
AU  - J.
AU  - A.
AU  - Speelman,
AU  - C.
AU  - P.
DA  - 01 Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10803-016-2854-x
DP  - Ovid Technologies
KW  - adhd
KW  - Autism
KW  - Cognition
KW  - Exercise intervention
KW  - Meta-analysis
KW  - attention deficit disorder
KW  - child
KW  - effect size
KW  - exercise
KW  - human
KW  - meta analysis
KW  - model
KW  - population
L1  - internal-pdf://2061029808/Tan-2016-A Meta-Analytic Review of the Efficac.pdf
LA  - English
M3  - Review
PY  - 2016
SP  - 3126-3143
T2  - Journal of Autism and Developmental Disorders
TI  - A Meta-Analytic Review of the Efficacy of Physical Exercise Interventions on Cognition in Individuals with Autism Spectrum Disorder and ADHD
UR  - http://www.wkap.nl/journalhome.htm/0162-3257http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=611223375http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1007%2Fs10803-016-2854-x&amp;issn=0162-3257&amp;isbn=&amp;volume=46&amp;issue=9&amp;spage=3126&amp;pages=3126-3143&amp;date=2016&amp;title=Journal+of+Autism+and+Developmental+Disorders&amp;atitle=A+Meta-Analytic+Review+of+the+Efficacy+of+Physical+Exercise+Interventions+on+Cognition+in+Individuals+with+Autism+Spectrum+Disorder+and+ADHD&amp;aulast=Tan&amp;pid=%3Cauthor%3ETan+B.W.Z.%3C%2Fauthor%3E%3CAN%3E611223375%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3E
UR  - http://download.springer.com/static/pdf/534/art%253A10.1007%252Fs10803-016-2854-x.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10803-016-2854-x&amp;token2=exp=1489069196~acl=%2Fstatic%2Fpdf%2F534%2Fart%25253A10.1007%25252Fs10803-016-2854-x.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10803-016-2854-x*~hmac=cba007ad990c328efca11500ed6df27466d0035f217028a0dbcde87f391e1344
VL  - 46
ER  -
TY  - JOUR
AB  - **Context **
Children from low-income and racial or ethnic minority populations in the U.S. are less likely to have a conventional source of medical care and more likely to develop chronic health problems than are more-affluent and non-Hispanic white children. They are more often chronically stressed, tired, and hungry, and more likely to have impaired vision and hearing - obstacles to lifetime educational achievement and predictors of adult morbidity and premature mortality. If school-based health centers (SBHCs) can overcome educational obstacles and increase receipt of needed medical services in disadvantaged populations, they can advance health equity. 

**Evidence acquisition **
A systematic literature search was conducted for papers published through July 2014. Using Community Guide systematic review methods, reviewers identified, abstracted, and summarized available evidence of the effectiveness of SBHCs on educational and health-related outcomes. Analyses were conducted in 2014-2015. 

**Evidence synthesis **
Most of the 46 studies included in the review evaluated onsite clinics serving urban, low-income, and racial or ethnic minority high school students. The presence and use of SBHCs were associated with improved educational (i.e., grade point average, grade promotion, suspension, and non-completion rates) and health-related outcomes (i.e., vaccination and other preventive services, asthma morbidity, emergency department use and hospital admissions, contraceptive use among females, prenatal care, birth weight, illegal substance use, and alcohol consumption). More services and more hours of availability were associated with greater reductions in emergency department overuse. 

**Conclusions **
Because SBHCs improve educational and health-related outcomes in disadvantaged students, they can be effective in advancing health equity. 

Copyright &copy; 2016 American Journal of Preventive Medicine.
AD  - (Knopf, Finnie, Peng, Hahn) Community Guide Branch, Division of Public Health Information Dissemination, CDC, MS E-69, 1600 Clifton Road, Atlanta, GA 30329-4207, United States (Truman) National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP), CDC, Atlanta, GA, United States (Vernon-Smiley, Hunt) NCHHSTP, CDC, Atlanta, GA, United States (Johnson) Emory University School of Medicine, Department of Pediatrics, Atlanta, GA, United States (Johnson) Rutgers New Jersey Medical School, Newark, NJ, United States (Fielding) UCLA Fielding School of Public Health, Los Angeles, CA, United States (Muntaner) University of Toronto, Bloomberg Faculty of Nursing, Toronto, ON, Canada (Phyllis Jones) Satcher Health Leadership Institute, Morehouse School of Medicine, Atlanta, GA, United States (Fullilove) Columbia University Mailman School of Public Health, New York, NY, United States R.A. Hahn, Community Guide Branch, Division of Public Health Information Dissemination, CDC, MS E-69, 1600 Clifton Road, Atlanta, GA 30329-4207, United States. E-mail: rhahn@cdc.gov
AN  - 610869933
AU  - Knopf,
AU  - J.
AU  - A.
AU  - Finnie,
AU  - R.
AU  - K.
AU  - C.
AU  - Peng,
AU  - Y.
AU  - Hahn,
AU  - R.
AU  - A.
AU  - Truman,
AU  - B.
AU  - I.
AU  - Vernon-Smiley,
AU  - M.
AU  - Johnson,
AU  - V.
AU  - C.
AU  - Johnson,
AU  - R.
AU  - L.
AU  - Fielding,
AU  - J.
AU  - E.
AU  - Muntaner,
AU  - C.
AU  - Hunt,
AU  - P.
AU  - C.
AU  - Phyllis-Jones,
AU  - C.
AU  - Fullilove,
AU  - M.
AU  - T.
DA  - 01 Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.amepre.2016.01.009
DP  - Ovid Technologies
KW  - alcohol consumption
KW  - ancestry group
KW  - article
KW  - asthma
KW  - birth weight
KW  - contraceptive behavior
KW  - emergency ward
KW  - ethnic group
KW  - health care availability
KW  - health center
KW  - health equity
KW  - high school student
KW  - hospital admission
KW  - human
KW  - lowest income group
KW  - morbidity
KW  - outcome assessment
KW  - prenatal care
KW  - primary medical care
KW  - quality control
KW  - school health service
KW  - substance use
KW  - systematic review
KW  - vaccination
KW  - alcohol
KW  - contraceptive agent
KW  - illicit drug
KW  - vaccine
KW  - drug overdose
KW  - female
KW  - preventive health service
KW  - suspension
KW  - synthesis
L1  - internal-pdf://2871666206/Knopf-2016-School-based health centers to adva.pdf
LA  - English
PY  - 2016
SP  - 114-126
T2  - American Journal of Preventive Medicine
TI  - School-based health centers to advance health equity: A community guide systematic review
UR  - http://www.elsevier.com/locate/ameprehttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18a&amp;AN=610869933http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.amepre.2016.01.009&amp;issn=0749-3797&amp;isbn=&amp;volume=51&amp;issue=1&amp;spage=114&amp;pages=114-126&amp;date=2016&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=School-based+health+centers+to+advance+health+equity%3A+A+community+guide+systematic+review&amp;aulast=Knopf&amp;pid=%3Cauthor%3EKnopf+J.A.%3C%2Fauthor%3E%3CAN%3E610869933%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0749379716000350/1-s2.0-S0749379716000350-main.pdf?_tid=fdf9aab0-04c9-11e7-bef2-00000aacb35e&amp;acdnat=1489065305_b36c756432a009e7288c3f89fbf53adb
VL  - 51
ER  -
TY  - GEN
AB  - **Background:** 
Preterm infants are often growth-restricted at hospital discharge. Feeding nutrient-enriched formula rather than standard formula to infants after hospital discharge might facilitate &#039;catch-up&#039; growth and might improve development.

**Objectives:**
To compare the effects of nutrient-enriched formula versus standard formula on growth and development of preterm infants after hospital discharge.

**Search methods:** 
We used the standard search strategy of the Cochrane Neonatal Review Group. This included searches of the Cochrane Central Register of Controlled Trials (2016, Issue 8) in the Cochrane Library, MEDLINE, Embase and the Cumulative Index to Nursing and Allied Health Literature (CINAHL; to 8 September 2016), as well as conference proceedings and previous reviews.

**Selection criteria:** 
Randomised and quasi-randomised controlled trials that compared the effects of feeding nutrient-enriched formula (postdischarge formula or preterm formula) versus standard term formula to preterm infants after hospital discharge. 

**Data collection and analysis:** 
Two review authors assessed trial eligibility and risk of bias and extracted data independently. We analysed treatment effects as described in the individual trials and reported risk ratios and risk differences for dichotomous data, and mean differences (MDs) for continuous data, with respective 95% confidence intervals (CIs). We used a fixed-effect model in meta-analyses and explored potential causes of heterogeneity by performing sensitivity analyses. We assessed quality of evidence at the outcome level using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.

**Main results:** 
We included 16 eligible trials with a total of 1251 infant participants. Trials were of variable methodological quality, with lack of allocation concealment and incomplete follow-up identified as major potential sources of bias. Trials (N = 11) that compared feeding infants with &#039;postdischarge formula&#039; (energy density about 74 kcal/100 mL) versus standard term formula (about 67 kcal/100 mL) did not find consistent evidence of effects on growth parameters up to 12 to 18 months post term. GRADE assessments indicated that evidence was of moderate quality, and that inconsistency within pooled estimates was the main quality issue.Trials (N = 5) that compared feeding with &#039;preterm formula&#039; (about 80 kcal/100 mL) versus term formula found evidence of higher rates of growth throughout infancy (weighted mean differences at 12 to 18 months post term: about 500 g in weight, 5 to 10 mm in length, 5 mm in head circumference). GRADE assessments indicated that evidence was of moderate quality, and that imprecision of estimates was the main quality issue.Few trials assessed neurodevelopmental outcomes, and these trials did not detect differences in developmental indices at 18 months post term. Data on growth or development through later childhood have not been provided.

**Authors&#039; conclusions:** 
Recommendations to prescribe &#039;postdischarge formula&#039; for preterm infants after hospital discharge are not supported by available evidence. Limited evidence suggests that feeding &#039;preterm formula&#039; (which is generally available only for in-hospital use) to preterm infants after hospital discharge may increase growth rates up to 18 months post term.
AN  - CD004696
AU  - Young,
AU  - L.
AU  - Embleton,
AU  - N.
AU  - D.
AU  - McGuire,
AU  - W.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004696.pub5
KW  - Infant Formula [standards]
KW  - Child Development [physiology]
KW  - Dietary Proteins [administration &amp; dosage]
KW  - Energy Intake [physiology]
KW  - Infant Nutritional Physiological Phenomena
KW  - Infant, Low Birth Weight [growth &amp; development]
KW  - Infant, Premature [growth &amp; development]
KW  - Patient Discharge
KW  - Randomized Controlled Trials as Topic
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Infant, Newborn[checkword]
L1  - internal-pdf://2447035741/Young-2016-Nutrient-enriched formula versus st.pdf
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Nutrient-enriched formula versus standard formula for preterm infants following hospital discharge
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004696.pub5/abstract
UR  - http://onlinelibrary.wiley.com/store/10.1002/14651858.CD004696.pub5/asset/CD004696.pdf?v=1&amp;t=j82wq28e&amp;s=3a4520489acc0604291ce8b76e334c74bebc8ed8
ER  -
TY  - JOUR
AB  - The main aim of this article is to identify systematic reviews of the effects of developmental prevention programs. 

These programs are defined as community-based programs designed to prevent antisocial behavior, targeted on children and adolescents, and aiming to change individual, family, or school risk factors. 

Only evaluations that reported effects on the outcomes of delinquency, offending, violence, aggression, or bullying were included. In total, 50 systematic reviews were assessed: five general reviews, 11 reviews of individually focused interventions, nine reviews of family-based programs, and 25 reviews of school-based programs. It was possible to calculate effect sizes from 33 reviews. 

Every summary odds ratio effect size was greater than 1, indicating that all types of programs were effective. The effect size was statistically significant in all except four cases. The median effect size was 1.46, which corresponds (on some reasonable assumptions) to a decrease in aggression of about one quarter. 

This article makes recommendations about how to improve systematic reviews and concludes that more investment in developmental prevention is warranted. 

Copyright &copy; 2016 Elsevier Ltd.
AD  - (Farrington, Gaffney, Losel, Ttofi) Institute of Criminology, Cambridge University, United Kingdom D.P. Farrington, Institute of Criminology, Cambridge University, United Kingdom
AN  - 614080649
AU  - Farrington,
AU  - D.
AU  - P.
AU  - Gaffney,
AU  - H.
AU  - Losel,
AU  - F.
AU  - Ttofi,
AU  - M.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.avb.2016.11.003
DP  - Ovid Technologies
KW  - Bullying
KW  - Delinquency
KW  - Developmental prevention
KW  - School programs
KW  - Systematic reviews
KW  - adolescent
KW  - child
KW  - effect size
KW  - family study
KW  - human
KW  - investment
KW  - odds ratio
KW  - prevention
KW  - risk factor
KW  - systematic review
KW  - violence
L1  - internal-pdf://1519509298/1-s2.0-S1359178916301963-main.pdf
LA  - English
M3  - In Press
N1  - Using Smart Source Parsing Date of Publication: August 2016
PY  - 2016
T2  - Aggression and Violent Behavior.
TI  - Systematic reviews of the effectiveness of developmental prevention programs in reducing delinquency, aggression, and bullying
UR  - http://www.elsevier.com/locate/aggviobehhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=614080649http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.avb.2016.11.003&amp;issn=1359-1789&amp;isbn=&amp;volume=&amp;issue=&amp;spage=no+pagination&amp;pages=no+pagination&amp;date=2016&amp;title=Aggression+and+Violent+Behavior&amp;atitle=Systematic+reviews+of+the+effectiveness+of+developmental+prevention+programs+in+reducing+delinquency%2C+aggression%2C+and+bullying&amp;aulast=Farrington&amp;pid=%3Cauthor%3EFarrington+D.P.%3C%2Fauthor%3E%3CAN%3E614080649%3C%2FAN%3E%3CDT%3EJournal%3A+Article+In+Press%3C%2FDT%3E
VL  - 16
ER  -
TY  - JOUR
AB  - **CONTEXT: **
Given the recent expansion of research in the area of music therapy (MT) for preterm infants, there is a need for an up-to-date meta-analysis of rigorously designed studies that focus exclusively on MT. 

**OBJECTIVE:**
To systematically review and meta-analyze the effect of MT on preterm infants and their parents during NICU hospitalization and after discharge from the hospital. 

**DATA SOURCES: **
PubMed/Medline, PsycINFO, Embase, Cochrane Database of Systematic Reviews, CINAHL, ERIC, Web of Science, RILM. 

**STUDY SELECTION: **
Only parallel or crossover randomized controlled trials of MT versus standard care, comparison therapy, or placebo were included. 

**DATA EXTRACTION: **
Independent extraction by 2 reviewers, including risk of bias indicators. 

**RESULTS: **
From 1803 relevant records, 16 met inclusion criteria, of which 14 contained appropriate data for meta-analysis involving 964 infant participants and 266 parent participants. Overall, random-effects meta-analyses suggested significant large effects favoring MT for infant respiratory rate (mean difference, -3.91/min, 95% confidence interval, -7.8 to -0.03) and maternal anxiety (standardized mean difference, -1.82, 95% confidence interval, -2.42 to -1.22). There was not enough evidence to confirm or refute any effects of MT on other physiologic and behavioral outcomes or on short-term infant and service-level outcomes. There was considerable heterogeneity between studies for the majority of outcomes. 

**LIMITATIONS: **
This review is limited by a lack of studies assessing long-term outcomes. 

**CONCLUSIONS: **
There is sufficient evidence to confirm a large, favorable effect of MT on infant respiratory rate and maternal anxiety. More rigorous research on short-term and long-term infant and parent outcomes is required. 

Copyright &copy; 2016 by the American Academy of Pediatrics.
AD  - Bieleninik, Lucja. The Grieg Academy Music Therapy Research Centre, Uni Research Health, Bergen, Norway; and. Ghetti, Claire. The Grieg Academy Department of Music, University of Bergen, Bergen, Norway. Gold, Christian. The Grieg Academy Music Therapy Research Centre, Uni Research Health, Bergen, Norway; and christian.gold@uni.no.
AN  - 27561729
AU  - Bieleninik,
AU  - L.
AU  - Ghetti,
AU  - C.
AU  - Gold,
AU  - C.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2016-0971
DP  - Ovid Technologies
J2  - Pediatrics
L1  - internal-pdf://1296930417/Bieleninik-2016-Music Therapy for Preterm Infa.pdf
LA  - English
M3  - Review
N1  - Bieleninik, Lucja Ghetti, Claire Gold, Christian Using Smart Source Parsing Sep e20160971 peds.2016-0971
PY  - 2016
T2  - Pediatrics
TI  - Music Therapy for Preterm Infants and Their Parents: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27561729http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27561729&amp;id=doi:10.1542%2Fpeds.2016-0971&amp;issn=0031-4005&amp;isbn=&amp;volume=138&amp;issue=3&amp;spage=e20160971&amp;pages=&amp;date=2016&amp;title=Pediatrics&amp;atitle=Music+Therapy+for+Preterm+Infants+and+Their+Parents%3A+A+Meta-analysis.&amp;aulast=Bieleninik&amp;pid=%3Cauthor%3EBieleninik+L%3C%2Fauthor%3E%3CAN%3E27561729%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 138
ER  -
TY  - JOUR
AB  - This meta-analysis examined the effect of transdiagnostic cognitive-behavioral therapy (T-CBT) in adults, children, and adolescents with emotional disorders, exploring the effects of possible moderator variables on efficacy. 

In contrast with previous reviews, only studies employing transdiagnostic theory-based protocols were included. 

A total of 48 studies reporting on 6291 participants were identified. Treatment efficacy was examined using a random effects model and taking into account pre- and post-treatment data. 

Results within the adult population showed large overall effect sizes on anxiety (randomized controlled trials [RCTs]: g = 0.80; Uncontrolled studies: g = 1.02) and depression (RCTs: g = 0.72; Uncontrolled studies: g = 1.08) that were stable at follow up. 

Preliminary analysis with children and adolescents showed medium effect sizes on anxiety (g = 0.45) and depression (g = 0.50). 

No significant differences between T-CBT and disorder-specific CBT were found. Overall, results support the efficacy of T-CBT for emotional disorders. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-02591-001
AU  - Garcia-Escalera,
AU  - J.
AU  - Chorot,
AU  - P.
AU  - Valiente,
AU  - R.
AU  - M.
AU  - Reales,
AU  - J.
AU  - M.
AU  - Sandin,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.5944/rppc.vol.21.num.3.2016.17811
L1  - internal-pdf://1870642881/Garcia-Escalera-2016-Efficacy of transdiagnost.pdf
PY  - 2016
SP  - 147-175
TI  - Efficacy of transdiagnostic cognitive-behavioral therapy for anxiety and depression in adults, children and adolescents: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-02591-001
VL  - 21
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
In addition to problems with attention and hyperactivity, children with ADHD present with poor organizational skills required for managing time and materials in academic projects. Organizational skills training (OST) has been increasingly used to address these deficits. We conducted a systematic review and meta-analysis of OST in children with ADHD. 

**OBJECTIVES: **
The objective of this study was to systematically review the evidence of the effects of OST for children with ADHD for organizational skills, attention, and academic performance. 

**METHODS: **
We searched 3 electronic databases to locate randomized controlled trials published in English in peer-reviewed journals comparing OST with parent education, treatment-as-usual, or waitlist control conditions. Standardized mean difference effect sizes from the studies were statistically combined using a random-effects meta-analyses across six outcomes: teacher- and parent-rated organizational skills, teacher- and parent-rated inattention, teacher-rated academic performance, and Grade Point Average (GPA). Risk of bias was assessed for randomization, allocation concealment, blinding of participants and treatment personnel, blinding of outcome assessors, incomplete outcome data, and selective outcome reporting. 

**RESULTS: **
Twelve studies involving 1054 children (576 treatment, 478 control) were included in the meta-analyses. Weighted mean effect sizes for teacher- and parent-rated outcome measures of organizational skills were g=0.54 (95% CI 0.17 to 0.91) and g=0.83 (95% CI 0.32 to 1.34), respectively. Weighted mean effect sizes of teacher- and parent-rated symptoms of inattention were g=0.26 (95% CI 0.01 to 0.52) and g=0.56 (95% CI 0.38 to 0.74), respectively. Weighted standardized mean effect size for teacher-rated academic performance and GPA were g=0.33 (95% CI 0.14 to 0.51) and g=0.29 (95% CI 0.07 to 0.51), respectively. 

**CONCLUSIONS: **
OST leads to moderate improvements in organizational skills of children with ADHD as rated by teachers and large improvements as rated by parents. More modest improvements were observed on the ratings of symptoms of inattention and academic performance. 

Protocol registration: prospero (crd42015019261). 

Copyright &copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Bikic, Aida. Child Study Center, Yale School of Medicine, 230 South Frontage Road, 06511 New Haven, Yale University, USA; Institute of Clinical Research, University of Southern Denmark, Winslowparken 19, Odense, Denmark. Electronic address: aida.bikic@rsyd.dk. Reichow, Brian. Child Study Center, Yale School of Medicine, 230 South Frontage Road, 06511 New Haven, Yale University, USA; Anita Zucker Center for Excellence in Early Childhood Studies, University of Florida, 1345 Norman Hall 618 SW 12th Street, Gainesville, USA. McCauley, Spencer A. Child Study Center, Yale School of Medicine, 230 South Frontage Road, 06511 New Haven, Yale University, USA. Ibrahim, Karim. Child Study Center, Yale School of Medicine, 230 South Frontage Road, 06511 New Haven, Yale University, USA. Sukhodolsky, Denis G. Child Study Center, Yale School of Medicine, 230 South Frontage Road, 06511 New Haven, Yale University, USA. Electronic address: denis.sukhodolsky@yale.edu.
AN  - 28088557
AU  - Bikic,
AU  - A.
AU  - Reichow,
AU  - B.
AU  - McCauley,
AU  - S.
AU  - A.
AU  - Ibrahim,
AU  - K.
AU  - Sukhodolsky,
AU  - D.
AU  - G.
DA  - Dec 29
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2016.12.004
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://2097649781/Bikic-2016-Meta-analysis of organizational ski.pdf
LA  - English
M3  - Review
N1  - Bikic, Aida Reichow, Brian McCauley, Spencer A Ibrahim, Karim Sukhodolsky, Denis G S0272-7358(15)30184-7
PY  - 2016
SP  - 108-123
T2  - Clinical Psychology Review
TI  - Meta-analysis of organizational skills interventions for children and adolescents with Attention-Deficit/Hyperactivity Disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=28088557http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:28088557&amp;id=doi:10.1016%2Fj.cpr.2016.12.004&amp;issn=0272-7358&amp;isbn=&amp;volume=52&amp;issue=&amp;spage=108&amp;pages=108-123&amp;date=2016&amp;title=Clinical+Psychology+Review&amp;atitle=Meta-analysis+of+organizational+skills+interventions+for+children+and+adolescents+with+Attention-Deficit%2FHyperactivity+Disorder.&amp;aulast=Bikic&amp;pid=%3Cauthor%3EBikic+A%3C%2Fauthor%3E%3CAN%3E28088557%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0272735815301847/1-s2.0-S0272735815301847-main.pdf?_tid=b3fd7d6c-04c2-11e7-9a91-00000aacb35f&amp;acdnat=1489062174_0d8f0caa802872d2a2956a26f0c222c0
VL  - 52
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Exergames have the potential to promote physical activity among children and adolescents. They also have other important benefits, but knowledge about other than the physical effects of exergaming remains thin. 

**AIM: **
To report the findings of a review of ten studies on the nonphysical effects of exergames on child and adolescent well-being. 

**DATA SOURCES: **
A broad search strategy was employed to identify relevant studies in CINAHL Ebsco Host, Ovid MEDLINE, Psycinfo ProQuest, Eric ProQuest, Scopus and Cochrane Library. The search timeframe was from January 2004 to April 2015. 

**REVIEW METHODS: **
A comprehensive systematic review without meta-analysis was conducted on 10 quantitative, qualitative and mixed-methods intervention studies. The quality of these studies was assessed following the guidelines of the Joanna Briggs Institute. The data were analysed using a narrative synthesis approach. 

**RESULTS: **
Exergaming was found to have some positive effects on self-concept, situational interest and motivation, enjoyment, psychological and social well-being, symptomatology and different learning experiences. However, two studies reported no effect on self-efficacy, and one study showed no intervention effect on self-esteem. The only follow-up study indicated that the enjoyment effect lasted for a few months. 

**CONCLUSION: **
Most of the studies reviewed found that exergaming had positive effects. However, more research evidence is still needed. In particular, there is a need for better-validated instruments and follow-up research. 

Copyright &copy; 2016 Nordic College of Caring Science.
AD  - Joronen, Katja. School of Health Sciences (Nursing Science), University of Tampere, Tampere, Finland. Aikasalo, Anna. School of Health Sciences (Nursing Science), University of Tampere, Tampere, Finland. Suvitie, Anne. School of Health Sciences (Nursing Science), University of Tampere, Tampere, Finland.
AN  - 27862145
AU  - Joronen,
AU  - K.
AU  - Aikasalo,
AU  - A.
AU  - Suvitie,
AU  - A.
DA  - Nov 16
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/scs.12393
DP  - Ovid Technologies
J2  - Scand J Caring Sci
L1  - internal-pdf://3325893347/Joronen_et_al-2016-Scandinavian_Journal_of_Car.pdf
LA  - English
M3  - Review
N1  - Joronen, Katja Aikasalo, Anna Suvitie, Anne Using Smart Source Parsing Nov
PY  - 2016
SP  - 16
T2  - Scandinavian Journal of Caring Sciences
TI  - Nonphysical effects of exergames on child and adolescent well-being: a comprehensive systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=27862145http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27862145&amp;id=doi:10.1111%2Fscs.12393&amp;issn=0283-9318&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2016&amp;title=Scandinavian+Journal+of+Caring+Sciences&amp;atitle=Nonphysical+effects+of+exergames+on+child+and+adolescent+well-being%3A+a+comprehensive+systematic+review.&amp;aulast=Joronen&amp;pid=%3Cauthor%3EJoronen+K%3C%2Fauthor%3E%3CAN%3E27862145%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 16
ER  -
TY  - JOUR
AB  - The purpose of this review was to systematically search and critically analyse the literature pertaining to behavioural outcomes of exercise interventions for individuals with autism spectrum disorder aged 16years. 

This systematic review employed a comprehensive peer-reviewed search strategy, two-stage screening process and rigorous critical appraisal, which resulted in the inclusion of 13 studies. 

Results demonstrated that exercise interventions consisting individually of jogging, horseback riding, martial arts, swimming or yoga/dance can result in improvements to numerous behavioural outcomes including stereotypic behaviours, social-emotional functioning, cognition and attention. 

Horseback riding and martial arts interventions may produce the greatest results with moderate to large effect sizes, respectively. 

Future research with well-controlled designs, standardized assessments, larger sample sizes and longitudinal follow-ups is necessary, in addition to a greater focus on early childhood (aged 0-5years) and adolescence (aged 12-16years), to better understand the extent of the behavioural benefits that exercise may provide these populations. 

Copyright &copy; The Author(s) 2016.
AD  - Bremer, Emily. Department of Kinesiology, McMaster University, Canada Infant and Child Health (INCH) Lab, Department of Family Medicine, McMaster University, Canada bremeree@mcmaster.ca. Crozier, Michael. Faculty of Health Sciences, University of Ontario Institute of Technology, Canada. Lloyd, Meghann. Faculty of Health Sciences, University of Ontario Institute of Technology, Canada.
AN  - 26823546
AU  - Bremer,
AU  - E.
AU  - Crozier,
AU  - N.
AU  - Lloyd,
AU  - M.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1362361315616002
DP  - Ovid Technologies
J2  - Autism
L1  - internal-pdf://2434572044/Bremer-2016-A systematic review of the behavio.pdf
LA  - English
M3  - Review
N1  - Bremer, Emily Crozier, Michael Lloyd, Meghann 1362361315616002
PY  - 2016
SP  - 899-915
T2  - Autism
TI  - A systematic review of the behavioural outcomes following exercise interventions for children and youth with autism spectrum disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26823546http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26823546&amp;id=doi:10.1177%2F1362361315616002&amp;issn=1362-3613&amp;isbn=&amp;volume=20&amp;issue=8&amp;spage=899&amp;pages=899-915&amp;date=2016&amp;title=Autism&amp;atitle=A+systematic+review+of+the+behavioural+outcomes+following+exercise+interventions+for+children+and+youth+with+autism+spectrum+disorder.&amp;aulast=Bremer&amp;pid=%3Cauthor%3EBremer+E%3C%2Fauthor%3E%3CAN%3E26823546%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 20
ER  -
TY  - JOUR
AB  - **Background:** 
The rising prevalence of autism spectrum disorder (ASD) has increased the need for evidence-based treatments to lessen the impact of symptoms. Presently, no therapies are available to effectively treat individuals with all of the symptoms of this disorder. It has been suggested that hyperbaric oxygen therapy may alleviate the biochemical dysfunction and clinical symptoms of ASD.

**Objectives:** 
To determine whether treatment with hyperbaric oxygen:1. improves core symptoms of ASD, including social communication problems and stereotypical and repetitive behaviors;2. improves noncore symptoms of ASD, such as challenging behaviors;3. improves comorbid states, such as depression and anxiety; and4. causes adverse effects.

**Search methods:** 
On 10 December 2015, we searched CENTRAL, Ovid MEDLINE, Embase, and 15 other databases, four of which were Chinese language databases. We also searched multiple trial and research registers.

**Selection criteria:** 
We selected randomized controlled trials (RCTs) and quasi-RCTs of any dose, duration, and frequency for hyperbaric oxygen therapy compared with no treatment or sham treatment for children and adults with ASD.

**Data collection and analysis:** 
We used standard methodological procedures expected by The Cochrane Collaboration, in that three review authors independently selected studies, assessed them for risk of bias, and extracted relevant data. We also assessed the quality of the evidence by using the GRADE approach.

**Main results:** 
We included one trial with a total of 60 children with a diagnosis of ASD who randomly received hyperbaric oxygen therapy or a sham treatment. Using GRADE criteria, we rated the quality of the evidence as low because of the small sample size and wide confidence intervals (CIs). Other problems included selection bias and short duration or follow-up.Overall, study authors reported no improvement in social interaction and communication, behavioral problems, communication and linguistic abilities, or cognitive function. With regard to the safety of hyperbaric oxygen therapy (adverse events), they reported minor-grade ear barotrauma events. Investigators found significant differences between groups in total number of side effect events (Peto odds ratio (OR) 3.87, 95% CI 1.53 to 9.82) and in the number of children who experienced side effects (Peto OR 4.40, 95% CI 1.33 to 14.48).

**Authors&#039; conclusions:** 
To date, there is no evidence that hyperbaric oxygen therapy improves core symptoms and associated symptoms of ASD. It is important to note that adverse effects (minor-grade ear barotrauma events) can occur. Given the absence of evidence of effectiveness and the limited biological plausibility and possible adverse effects, the need for future RCTs of hyperbaric oxygen therapy must be carefully considered.
AN  - CD010922
AU  - Xiong,
AU  - T.
AU  - Chen,
AU  - H.
AU  - Luo,
AU  - R.
AU  - Mu,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd010922.pub2
L1  - internal-pdf://2407272519/Xiong_et_al-2016-.pdf
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Hyperbaric oxygen therapy for people with autism spectrum disorder (ASD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD010922.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD010922.pub2/asset/CD010922.pdf?v=1&amp;t=iw7jq3qw&amp;s=5489383994c873b802cc873ef1970d10bcc36d1f
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Although spoken-language deficits are not core to an autism spectrum disorder (ASD) diagnosis, many children with ASD do present with delays in this area. Previous meta-analyses have assessed the effects of intervention on reducing autism symptomatology, but have not determined if intervention improves spoken language. This analysis examines the effects of early interventions on spoken-language in children with ASD. 

**METHOD:**
A systematic review of 1756 studies of children with ASD who participated in early intervention resulted in the inclusion of 26 studies in the current review. These studies included 1738 participants with ASD who were, on average, 3.3years old (SD=0.91). 

**RESULTS: **
This random-effects meta-analysis of spoken-language outcomes for children with ASD who received early intervention as compared with usual treatments yielded a significant overall mean effect size of g=0.26 (CI=0.11 to 0.42). On average, children with ASD significantly increased their use of spoken-language following experimental early interventions. Treatments delivered simultaneously by a clinician and a parent resulted in greater gains in spoken-language than treatments delivered by a clinician or parent only. No other participant or study characteristics predicted individual-study effect sizes. 

**CONCLUSIONS: **
Early intervention improves spoken-language outcomes for children with ASD, and the largest effects are found when both parent and clinician implement the intervention. Recommendations for practice include adding systematic parent training to interventions for spoken language to potentially improve outcomes. Future research should report standard language measures as well as child (cognitive ability and socio-economic status) and intervention characteristics to improve evidence related to the effects of interventions on spoken communication in children with ASD. 

Copyright &copy; 2016 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley &amp; Sons Ltd.
AD  - Hampton, L H. Vanderbilt University, Nashville, TN, USA. Kaiser, A P. Vanderbilt University, Nashville, TN, USA.
AN  - 27120988
AU  - Hampton,
AU  - L.
AU  - H.
AU  - Kaiser,
AU  - A.
AU  - P.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jir.12283
DP  - Ovid Technologies
J2  - J Intellect Disabil Res
L1  - internal-pdf://2927622263/Hampton-2016-Intervention effects on spoken-la.pdf
LA  - English
N1  - Hampton, L H Kaiser, A P
PY  - 2016
SP  - 444-63
T2  - Journal of Intellectual Disability Research
TI  - Intervention effects on spoken-language outcomes for children with autism: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27120988http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27120988&amp;id=doi:10.1111%2Fjir.12283&amp;issn=0964-2633&amp;isbn=&amp;volume=60&amp;issue=5&amp;spage=444&amp;pages=444-63&amp;date=2016&amp;title=Journal+of+Intellectual+Disability+Research&amp;atitle=Intervention+effects+on+spoken-language+outcomes+for+children+with+autism%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Hampton&amp;pid=%3Cauthor%3EHampton+LH%3C%2Fauthor%3E%3CAN%3E27120988%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1111/jir.12283/asset/jir12283.pdf?v=1&amp;t=j02edr2z&amp;s=9cfb4740548bfef7c24a1bae41a056c782383b29
VL  - 60
ER  -
TY  - JOUR
AB  - **Background:** 
Emotional and behavioural problems in children are common. Research suggests that parenting has an important role to play in helping children to become well-adjusted, and that the first few months and years are especially important. Parenting programmes may have a role to play in improving the emotional and behavioural adjustment of infants and toddlers, and this review examined their effectiveness with parents and carers of young children.

**Objectives:** 1. To establish whether group-based parenting programmes are effective in improving the emotional and behavioural adjustment of young children (maximum mean age of three years and 11 months); and 2. To assess whether parenting programmes are effective in the primary prevention of emotional and behavioural problems.

**Search methods:** 
In July 2015 we searched CENTRAL (the Cochrane Library), Ovid MEDLINE, Embase (Ovid), and 10 other databases. We also searched two trial registers and handsearched reference lists of included studies and relevant systematic reviews.

**Selection criteria:** 
Two reviewers independently assessed the records retrieved by the search. We included randomised controlled trials (RCTs) and quasi-RCTs of group-based parenting programmes that had used at least one standardised instrument to measure emotional and behavioural adjustment in children.

**Data collection and analysis:** 
One reviewer extracted data and a second reviewer checked the extracted data. We presented the results for each outcome in each study as standardised mean differences (SMDs) with 95% confidence intervals (CIs). Where appropriate, we combined the results in a meta-analysis using a random-effects model. We used the GRADE (Grades of Recommendations, Assessment, Development, and Evaluation) approach to assess the overall quality of the body of evidence for each outcome.

**Main results:** 
We identified 22 RCTs and two quasi-RCTs evaluating the effectiveness of group-based parenting programmes in improving the emotional and behavioural adjustment of children aged up to three years and 11 months (maximum mean age three years 11 months).The total number of participants in the studies were 3161 parents and their young children. Eight studies were conducted in the USA, five in the UK, four in Canada, five in Australia, one in Mexico, and one in Peru. All of the included studies were of behavioural, cognitive-behavioural or videotape modelling parenting programmes.We judged 50% (or more) of the included studies to be at low risk for selection bias, detection bias (observer-reported outcomes), attrition bias, selective reporting bias, and other bias. As it is not possible to blind participants and personnel to the type of intervention in these trials, we judged all studies to have high risk of performance bias. Also, there was a high risk of detection bias in the 20 studies that included parent-reported outcomes.The results provide evidence that group-based parenting programmes reduce overall emotional and behavioural problems (SMD -0.81, 95% CI -1.37 to -0.25; 5 studies, 280 participants, low quality evidence) based on total parent-reported data assessed at postintervention. This result was not, however, maintained when two quasi-RCTs were removed as part of a sensitivity analysis (SMD -0.67, 95% CI -1.43 to 0.09; 3 studies, 221 participants). The results of data from subscales show evidence of reduced total externalising problems (SMD -0.23, 95% CI -0.46 to -0.01; 8 studies, 989 participants, moderate quality evidence). Single study results show very low quality evidence of reductions in externalising problems hyperactivity-inattention subscale (SMD -1.34; 95% CI -2.37 to -0.31; 19 participants), low quality evidence of no effect on total internalising problems (SMD 0.34; 95% CI -0.12 to 0.81; 73 participants), and very low quality evidence of an increase in social skills (SMD 3.59; 95% CI 2.42 to 4.76; 32 participants), based on parent-reported data assessed at postintervention. Results for secondary outcomes, which were also measured using subscales, show an impact on parent-child interac on in terms of reduced negative behaviour (SMD -0.22, 95% CI -0.39 to -0.06; 7 studies, 941 participants, moderate quality evidence), and improved positive behaviour (SMD 0.48, 95% CI 0.17 to 0.79; 4 studies, 173 participants, moderate quality evidence) as rated by independent observers postintervention. No further meta-analyses were possible. Results of subgroup analyses show no evidence for treatment duration (seven weeks or less versus more than eight weeks) and inconclusive evidence for prevention versus treatment interventions.

**Authors&#039; conclusions:** 
The findings of this review, which relate to the broad group of universal and at-risk (targeted) children and parents, provide tentative support for the use of group-based parenting programmes to improve the overall emotional and behavioural adjustment of children with a maximum mean age of three years and 11 months, in the short-term. There is, however, a need for more research regarding the role that these programmes might play in the primary prevention of both emotional and behavioural problems, and their long-term effectiveness.
AN  - CD003680
AU  - Barlow,
AU  - J.
AU  - Bergman,
AU  - H.
AU  - Kornør,
AU  - H.
AU  - Wei,
AU  - Y.
AU  - Bennett,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003680.pub3
KW  - Infant Behavior
KW  - Mental Health
KW  - Parenting
KW  - Program Evaluation
KW  - Child Behavior Disorders [prevention &amp; control]
KW  - Child Development
KW  - Child Rearing
KW  - Emotions
KW  - Randomized Controlled Trials as Topic
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Infant, Newborn[checkword]
KW  - Behav
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Group-based parent training programmes for improving emotional and behavioural adjustment in young children
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003680.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003680.pub3/asset/CD003680.pdf?v=1&amp;t=iw7jkdo1&amp;s=d6295bd9f21bee0c3114e8a904a1206cb11404b0
ER  -
TY  - JOUR
AB  - Children in foster care have high rates of adverse childhood experiences and are at risk for mental health problems. These problems can be difficult to ameliorate, creating a need for rigorous intervention research. 

Previous research suggests that intervening with children in foster care can be challenging for several reasons, including the severity and complexity of their mental health problems, and challenges engaging this often transitory population in mental health services. 

The goal of this article was to systematically review the intervention research that has been conducted with children in foster care, and to identify future research directions. This review was conducted on mental health interventions for children, ages 0 to 12, in foster care, using ERIC, CINAHL, PsycINFO, PubMed, ProQuest&#039;s Dissertation and Theses Database, Social Services Abstracts, and Social Work Abstracts. It was restricted to interventions that are at least &quot;possibly efficacious&quot; (i.e., supported by evidence from at least one randomized controlled trial). 

Studies were evaluated for risk of bias. Ten interventions were identified, with diverse outcomes, including mental health and physiological. Six interventions were developed for children in foster care. 

Interventions not developed for children in foster care were typically adapted to the foster context. Most interventions have yet to be rigorously evaluated in community-based settings with children in foster care. 

Little research has been conducted on child and family engagement within these interventions, and there is a need for more research on moderators of intervention outcomes and subgroups that benefit most from these interventions. In addition, there is no consensus regarding how to adapt interventions to this population. 

Future research should focus on developing and testing more interventions with this population, rigorously evaluating their effectiveness in community-based settings, determining necessary adaptations, and identifying which interventions work best for whom. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Hambrick, Erin P.: hambricke@umkc.edu Hambrick, Erin P.: University of Missouri-Kansas City, Department of Psychology, 5030 Cherry Street, Room 309, Kansas City, MO, US, 64110, hambricke@umkc.edu Hambrick, Erin P.: Kempe Center for the Prevention and Treatment of Child Abuse and Neglect, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO, US Oppenheim-Weller, Shani: Kempe Center for the Prevention and Treatment of Child Abuse and Neglect, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO, US N&#039;zi, Amanda M.: Kempe Center for the Prevention and Treatment of Child Abuse and Neglect, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO, US Taussig, Heather N.: Kempe Center for the Prevention and Treatment of Child Abuse and Neglect, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO, US
AN  - 2016-53393-009
AU  - Hambrick,
AU  - E.
AU  - P.
AU  - Oppenheim-Weller,
AU  - S.
AU  - N&#039;zi,
AU  - A.
AU  - M.
AU  - Taussig,H.
AU  - N.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2016.09.002
DP  - Ovid Technologies
KW  - Foster care, Interventions, Treatment, Systematic review, Child maltreatment, engagement
KW  - *Foster Care
KW  - *Foster Children
KW  - *Intervention
KW  - *Mental Health
KW  - Risk Factors
KW  - Social Services
KW  - Community &amp; Social Services [3373]
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://1746204650/Hambrick-2016-Mental health interventions for.pdf
LA  - English
M3  - Empirical Study; Literature Review; Systematic Review; Qualitative Study
PY  - 2016
SP  - 65-77
T2  - Children and Youth Services Review
TI  - Mental health interventions for children in foster care: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-53393-009http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2016.09.002&amp;issn=0190-7409&amp;isbn=&amp;volume=70&amp;issue=&amp;spage=65&amp;pages=65-77&amp;date=2016&amp;title=Children+and+Youth+Services+Review&amp;atitle=Mental+health+interventions+for+children+in+foster+care%3A+A+systematic+review.&amp;aulast=Hambrick&amp;pid=%3Cauthor%3EHambrick%2C+Erin+P%3C%2Fauthor%3E%3CAN%3E2016-53393-009%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0190740916302717/1-s2.0-S0190740916302717-main.pdf?_tid=c7b01464-04c7-11e7-8be5-00000aacb35f&amp;acdnat=1489064355_ade621d18ae2128bcc80002cc7a8e6f3
VL  - 70
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Aripiprazole, an atypical antipsychotic drug, has shown potential as a promising candidate for the treatment of Tourette&#039;s disorder (TD). However, the effectiveness and the tolerability profile of aripiprazole in the reduction of tics in children and adolescents with TD have not been systematically analyzed. This meta-analysis aimed to evaluate the effectiveness and tolerability of aripiprazole in children and adolescents with TD. 

**METHODS:** 
We searched for clinical trials that investigated the effect of aripiprazole in children and adolescents with TD in PubMed and Web of Science. The outcomes of interest comprised the Yale Global Tic Severity Score (YGTSS) total tic scores and the Clinical Global Impressions Scale for Tic Severity (CGI-S) scores. The pooled effect size (ES) and 95% confidence interval (CI) were calculated to assess the effectiveness of aripiprazole in children and adolescents with TD. 

**RESULTS: **
Ten studies were retrieved from 122 citations for the analysis, and in total, 302 patients (mean age, 11.6 years; median follow-up, 9 weeks) were included in the analysis. After synthesis of the data, the meta-analysis showed significantly greater improvement in the mean change in the YGTSS total tic scores (ES=-1.99, 95% CI=[-2.26]-[-1.72]; p=0.001) and the mean CGI-S scores (ES=-2.34, 95% CI=[-2.96]-[-1.73]; p=0.001) from pretreatment to posttreatment. Adverse events were reported in nine trials. Drowsiness (28.5%), nausea (20.2%), and headache (13.8%) were common adverse events. 

**CONCLUSIONS: **
The use of aripiprazole is safe, and shows therapeutic effectiveness in children and adolescents with TD.
AD  - Liu, Yueying. 1 Department of Pediatrics, Affiliated Hospital, Jiangnan University , Wuxi, Jiangsu, China . Ni, Hong. 2 Neurology Laboratory, Soochow University Affiliated Children&#039;s Hospital , Suzhou, Jiangsu, China . Wang, Chunhong. 1 Department of Pediatrics, Affiliated Hospital, Jiangnan University , Wuxi, Jiangsu, China . Li, Lili. 2 Neurology Laboratory, Soochow University Affiliated Children&#039;s Hospital , Suzhou, Jiangsu, China . Cheng, Zaohuo. 3 Department of Clinical Psychology, Wuxi Mental Health Center affiliated to Nanjing Medical University , Wuxi, Jiangsu, China . Weng, Zhen. 4 Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine and i-Lab, Suzhou Institute of Nano-Tech and Nano-Bionics , Chinese Academy of Sciences, Suzhou, Jiangsu, China .
AN  - 26914764
AU  - Liu,
AU  - Y.
AU  - Ni,
AU  - H.
AU  - Wang,
AU  - C.
AU  - Li,
AU  - L.
AU  - Cheng,
AU  - Z.
AU  - Weng,
AU  - Z.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1089/cap.2015.0125
DP  - Ovid Technologies
J2  - J Child Adolesc Psychopharmacol
L1  - internal-pdf://2496809896/Liu-2016-Effectiveness and Tolerability of Ari.pdf
LA  - English
N1  - Liu, Yueying Ni, Hong Wang, Chunhong Li, Lili Cheng, Zaohuo Weng, Zhen
PY  - 2016
SP  - 436-41
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - Effectiveness and Tolerability of Aripiprazole in Children and Adolescents with Tourette&#039;s Disorder: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26914764http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26914764&amp;id=doi:10.1089%2Fcap.2015.0125&amp;issn=1044-5463&amp;isbn=&amp;volume=26&amp;issue=5&amp;spage=436&amp;pages=436-41&amp;date=2016&amp;title=Journal+of+Child+%26+Adolescent+Psychopharmacology&amp;atitle=Effectiveness+and+Tolerability+of+Aripiprazole+in+Children+and+Adolescents+with+Tourette%27s+Disorder%3A+A+Meta-Analysis.&amp;aulast=Liu&amp;pid=%3Cauthor%3ELiu+Y%3C%2Fauthor%3E%3CAN%3E26914764%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://online.liebertpub.com/doi/pdfplus/10.1089/cap.2015.0125
VL  - 26
ER  -
TY  - JOUR
AB  - **Background: **
We systematically reviewed and meta-analysed evaluations testing the effectiveness of positive youth development (PYD) interventions for reducing violence in young people.

**Methods: **
Two reviewers working independently screened records, assessed full-text studies for inclusion and extracted data. Outcomes were transformed to Cohen&#039;s d. Quality assessment of included evaluations was undertaken using the Cochrane risk of bias tool. Effect sizes were combined using multilevel meta-analysis. We searched 21 databases, including MEDLINE, PsycINFO, CINAHL and CENTRAL, and hand-searched key journals and websites. We included studies where the majority of participants were aged 11-18 years and where interventions were delivered in community (not clinical or judicial) settings outside of normal school hours. We excluded studies targeting predefined physical and mental health conditions or parents/carers alongside young people. We defined violence as perpetration or victimisation of physical violence including violent crime. 

**Results: **
Three randomised trials were included in this systematic review. Included evaluations each had design flaws. Meta-analyses suggested that PYD interventions did not have a statistically significant effect on violence outcomes across all time points (d = 0.021, 95% CI -0.050 to 0.093), though interventions did have a statistically significant short-term effect (d = 0.076, 95% CI 0.013 to 0.140). 

**Conclusions: **
Our meta-analyses do not offer evidence of PYD interventions in general having effects of public health significance in reducing violence among young people. Evaluations did not consistently report theories of change or implementation fidelity, so it is unclear if our meta-analyses provide evidence that the PYD theory of change is ineffective in reducing violence among young people. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2016-61648-001
AU  - Melendez-Torres,
AU  - G.
AU  - Dickson,
AU  - K.
AU  - Fletcher,
AU  - A.
AU  - Thomas,
AU  - J.
AU  - Hinds,
AU  - K.
AU  - Campbell,
AU  - R.
AU  - Murphy,
AU  - S.
AU  - Bonell,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/jech-2015-206132
L1  - internal-pdf://3909280781/Melendez-Torres-2016-Systematic review and met.pdf
PY  - 2016
SP  - 171-177
T2  - Journal of Epidemiology and Community Health
TI  - Systematic review and meta-analysis of effects of community-delivered positive youth development interventions on violence outcomes
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-61648-001
VL  - 70
ER  -
TY  - JOUR
AB  - The Good Behavior Game (GBG) is a classroom management strategy that uses an interdependent group-oriented contingency to promote prosocial behavior and decrease problem behavior. 

This meta-analysis synthesized single-case research (SCR) on the GBG across 21 studies, representing 1,580 students in pre-kindergarten through Grade 12. 

The TauU effect size across 137 phase contrasts was .82 with a confidence interval 95% CI = [0.78, 0.87], indicating a substantial reduction in problem behavior and an increase in prosocial behavior for participating students. 

Five potential moderators were examined: emotional and behavioral disorder (EBD) risk status, reinforcement frequency, target behaviors, GBG format, and grade level. 

Findings suggest that the GBG is most effective in reducing disruptive and off-task behaviors, and that students with or at risk for EBD benefit most from the intervention. Implications for research and practice are discussed.
AD  - [Bowman-Perrott, Lisa; Burke, Mack D.; Zaini, Samar; Zhang, Nan; Vannest, Kimberly] Texas A&amp;M Univ, College Stn, TX 77843 USA. Bowman-Perrott, L (reprint author), Texas A&amp;M Univ, College Stn, TX 77843 USA. lbperrott@tamu.edu
AN  - WOS:000378879100006
AU  - Bowman-Perrott,
AU  - L.
AU  - Burke,
AU  - M.
AU  - D.
AU  - Zaini,
AU  - S.
AU  - Zhang,
AU  - N.
AU  - Vannest,
AU  - K.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1098300715592355
J2  - J. Posit. Behav. Interv.
KW  - behavior(s)
KW  - challenging
KW  - intervention(s)
KW  - single-case designs
KW  - meta-analysis
KW  - studies
KW  - independent group contingencies
KW  - disruptive behavior
KW  - classroom-behavior
KW  - elementary-school
KW  - effect sizes
KW  - students
KW  - reinforcement
KW  - management
KW  - education
KW  - Psychology
KW  - Education &amp; Educational Research
L1  - internal-pdf://0390700156/GBG.JPBI.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: DQ0HE Times Cited: 0 Cited Reference Count: 66 Bowman-Perrott, Lisa Burke, Mack D. Zaini, Samar Zhang, Nan Vannest, Kimberly 0 16 Sage publications inc Thousand oaks 1538-4772
PY  - 2016
SP  - 180-190
T2  - Journal of Positive Behavior Interventions
TI  - Promoting Positive Behavior Using the Good Behavior Game: A Meta-Analysis of Single-Case Research
UR  - &lt;Go to ISI&gt;://WOS:000378879100006
VL  - 18
ER  -
TY  - JOUR
AB  - **Background: **
Secure attachment is associated with optimal outcomes across all domains in childhood, and both insecure and disorganised attachment are associated with a range of later psychopathologies. Insecure and disorganised attachment are common, particularly in disadvantaged populations, pointing to the need to identify effective methods of addressing such problems. 

**Aims: **
This paper presents the findings of a review of secondary and primary studies evaluating the effectiveness of interventions aimed at improving attachment and attachment-related outcomes on a universal, targeted or indicated basis, which was undertaken as part of an update of the evidence base for a UK-based national programme targeting children aged 0-5 years (Healthy Child Programme). 

**Method: **
A systematic search of key electronic databases was undertaken to identify secondary and primary sources of data that addressed the research question and that had been published between 2008 and 2014; search sources included Cochrane Collaboration, NICE, EPPI Centre, Campbell Collaboration and PubMed, PsycInfo, CINAHL databases. 

**Findings: **
Six systematic reviews and 11 randomised controlled trials were identified that had evaluated the effectiveness of universal, selective or indicated interventions aimed at improving attachment and attachment-related outcomes in children aged 0-5 years. Potentially effective methods of improving infant attachment include parent-infant psychotherapy, video feedback and mentalisation-based programmes. Methods that appear to be effective in improving attachment-related outcomes include home visiting and parenting programmes. 

**Conclusions: **
A number of methods of working to promote attachment and attachment-related outcomes in preschool children are now being recommended as part of the Healthy Child Programme. The implications in terms of the role and contribution of practitioners working in child and adolescent mental health service are discussed. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AD  - Barlow, Jane: jane.barlow@warwick.ac.uk Barlow, Jane: Health Services Research Unit, Warwick Medical School, University of Warwick, Medical School Building, Gibbet Hill Road, Coventry, United Kingdom, CV4 7AL, jane.barlow@warwick.ac.uk Barlow, Jane: Health Services Research Unit, Warwick Medical School, University of Warwick, Coventry, United Kingdom Schrader-McMillan, Anita: Health Services Research Unit, Warwick Medical School, University of Warwick, Coventry, United Kingdom Axford, Nick: Dartington Social Research Unit, Totnes, United Kingdom Wrigley, Zoe: Dartington Social Research Unit, Totnes, United Kingdom Sonthalia, Shreya: Dartington Social Research Unit, Totnes, United Kingdom Wilkinson, Tom: Dartington Social Research Unit, Totnes, United Kingdom Rawsthorn, Michaela: Dartington Social Research Unit, Totnes, United Kingdom Toft, Alex: Centre for Children and Families Applied Research (CCFAR), Coventry University, Coventry, United Kingdom Coad, Jane: Centre for Children and Families Applied Research (CCFAR), Coventry University, Coventry, United Kingdom
AN  - 2015-53790-001
AU  - Barlow,
AU  - J.
AU  - Schrader-McMillan,
AU  - A.
AU  - Nick,
AU  - A.
AU  - Wrigley,
AU  - Z.
AU  - Sonthalia,
AU  - S.
AU  - Wilkinson,
AU  - T.
AU  - Rawsthorn,
AU  - M.
AU  - Toft,
AU  - A.
AU  - Coad,
AU  - J.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/camh.12138
DP  - Ovid Technologies
KW  - Healthy Child Programme, 0-5 years, intervention, attachment, parental sensitivity, early years
KW  - *Attachment Behavior
KW  - *Child Psychiatry
KW  - *Child Psychology
KW  - *Early Intervention
KW  - *Preschool Students
KW  - Psychopathology
KW  - Health &amp; Mental Health Services [3370]
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://1527482909/Barlow_et_al-2016-Child_and_Adolescent_Mental_.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2016
SP  - 11-20
T2  - Child and Adolescent Mental Health
TI  - Review: Attachment and attachment-related outcomes in preschool children-A review of recent evidence
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-53790-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1111%2Fcamh.12138&amp;issn=1475-357X&amp;isbn=&amp;volume=21&amp;issue=1&amp;spage=11&amp;pages=11-20&amp;date=2016&amp;title=Child+and+Adolescent+Mental+Health&amp;atitle=Review%3A+Attachment+and+attachment-related+outcomes+in+preschool+children-A+review+of+recent+evidence.&amp;aulast=Barlow&amp;pid=%3Cauthor%3EBarlow%2C+Jane%3C%2Fauthor%3E%3CAN%3E2015-53790-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 21
ER  -
TY  - JOUR
AB  - **Objective **
To determine whether an up-to-date systematic review and meta-analysis of observational studies would support the previously suggested associations regarding prenatal selective serotonin reuptake inhibitor (SSRI) use and the risk for autism spectrum disorders (ASD) in children. 

**Methods **
PubMed/MEDLINE, Cochrane Central Register of Controlled Trials and Reprotox databases were searched; observational studies with an exposed and unexposed group were included. 

**Results **
The meta-analysis of case-control studies demonstrated a significantly increased risk of ASD in the children whose mothers were prenatally exposed to SSRIs during different exposure time windows (except third trimester). The qualitative review of the cohort studies suggested inconsistent findings. 

**Conclusions **
The significant association between preconception-only SSRI exposure and ASD in the children and negative/inconsistent findings among cohort studies weaken the significant associations detected in this meta-analysis. We suggest that confounding by indication still cannot be ruled out regarding prenatal SSRI exposure and ASD in children. 

Copyright &copy; 2016 Elsevier Inc.
AD  - (Kaplan, Keskin-Arslan, Acar) Terafar - Izmir Katip Celebi University Teratology Information, Training and Research Center, Izmir, Turkey (Kaplan, Keskin-Arslan, Acar) Izmir Katip Celebi University School of Medicine, Department of Pharmacology Izmir, Turkey (Sozmen) Izmir Katip Celebi University School of Medicine, Department of Public Health, Izmir, Turkey Y.C. Kaplan, Izmir Katip Celebi Universitesi Ataturk Egitim ve Arastirma Hastanesi, Klinik Farmakoloji ve Toksikoloji Birimi, Karabaglar, Izmir 35360, Turkey. E-mail: seawise@gmail.com
AN  - 612318523
AU  - Kaplan,
AU  - Y.
AU  - C.
AU  - Keskin-Arslan,
AU  - E.
AU  - Acar,
AU  - C.
AU  - Sozmen,
AU  - K.
DA  - 01 Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.reprotox.2016.09.013
DP  - Ovid Technologies
KW  - Antidepressants
KW  - Antidepressive agents
KW  - Autism
KW  - Autism spectrum disorder
KW  - Autistic disorder
KW  - Pregnancy
KW  - Serotonin uptake inhibitors
KW  - ssri
KW  - analytic method
KW  - article
KW  - case control study
KW  - child
KW  - cohort analysis
KW  - depression/dt [Drug Therapy]
KW  - drug use
KW  - human
KW  - meta analysis
KW  - mother
KW  - observational study
KW  - outcome assessment
KW  - prenatal drug exposure
KW  - risk assessment
KW  - systematic review
KW  - serotonin uptake inhibitor/dt [Drug Therapy]
KW  - serotonin uptake inhibitor/to [Drug Toxicity]
KW  - Cochrane Library
KW  - exposure
KW  - female
KW  - Medline
KW  - third trimester pregnancy
KW  - serotonin uptake inhibitor
L1  - internal-pdf://2953453041/Kaplan-2016-Prenatal selective serotonin reupt.pdf
LA  - English
PY  - 2016
SP  - 31-43
T2  - Reproductive Toxicology
TI  - Prenatal selective serotonin reuptake inhibitor use and the risk of autism spectrum disorder in children: A systematic review and meta-analysis
UR  - http://www.elsevier.com/inca/publications/store/5/2/5/4/8/9/index.htthttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=612318523http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.reprotox.2016.09.013&amp;issn=0890-6238&amp;isbn=&amp;volume=66&amp;issue=&amp;spage=31&amp;pages=31-43&amp;date=2016&amp;title=Reproductive+Toxicology&amp;atitle=Prenatal+selective+serotonin+reuptake+inhibitor+use+and+the+risk+of+autism+spectrum+disorder+in+children%3A+A+systematic+review+and+meta-analysis&amp;aulast=Kaplan&amp;pid=%3Cauthor%3EKaplan+Y.C.%3C%2Fauthor%3E%3CAN%3E612318523%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0890623816303471/1-s2.0-S0890623816303471-main.pdf?_tid=9d96b96a-04c9-11e7-a7a4-00000aacb35f&amp;acdnat=1489065143_3768f567f998c58663cbca40c275349e
VL  - 66
ER  -
TY  - JOUR
AB  - Children with autism spectrum disorders (ASDs) may struggle to self-regulate their learning, and such difficulty may be especially notable in the area of written expression. 

One intervention that has explored self-regulation in writing is the self-regulated strategy development (SRSD) approach. In this article, a review of the research using SRSD to teach children with ASD to write is conducted. 

Investigation yielded 11 studies including 27 participants with ASD. Results of the review indicated that students with ASD taught using an SRSD approach can improve their overall quality of writing, their discourse elements (e.g., persuasive or story) utilized, and the length of their products. 

Self-regulatory abilities, such as self-monitoring and planning, were also noted to improve. Suggestions for practice and future research are provided.
AD  - [Asaro-Saddler, Kristie] SUNY Albany, 1400 Washington Ave,228, Albany, NY 12222 USA. Asaro-Saddler, K (reprint author), SUNY Albany, 1400 Washington Ave,228, Albany, NY 12222 USA. ksaddler@albany.edu
AN  - WOS:000384123700006
AU  - Asaro-Saddler,
AU  - K.
DA  - Jul-Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/TLD.0000000000000093
J2  - Top. Lang. Disord.
KW  - autism spectrum disorder
KW  - self-regulated strategy development (SRSD)
KW  - self-regulation
KW  - strategy instruction
KW  - writing instruction
KW  - written
KW  - expression
KW  - high-functioning autism
KW  - written-language performance
KW  - asperger-syndrome
KW  - strategy-development
KW  - children
KW  - writers
KW  - interventions
KW  - management
KW  - improve
KW  - school
KW  - Linguistics
KW  - Rehabilitation
L1  - internal-pdf://1718846326/WritingInstructionandSelfRegulationforStudents.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: DX1JR Times Cited: 2 Cited Reference Count: 51 Asaro-Saddler, Kristie 2 1 Lippincott williams &amp; wilkins Philadelphia 1550-3259
PY  - 2016
SP  - 266-283
T2  - Topics in Language Disorders
TI  - Writing Instruction and Self-Regulation for Students With Autism Spectrum Disorders: A Systematic Review of the Literature
UR  - &lt;Go to ISI&gt;://WOS:000384123700006
VL  - 36
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Despite recognition that psychosocial interventions can improve quality of life and mental health, there continues to be a lack of clarity and guidance around effective psychosocial interventions for children and young people with epilepsy. This review utilizes specific quality criteria to systematically identify and appraise the evidence for the effectiveness of psychosocial interventions for children and young people with epilepsy. 

**METHODS: **
A systematic search of six electronic databases was conducted using predefined eligibility criteria. The reference lists of previous review papers were also manually searched. Seventeen studies met the inclusion and exclusion criteria. A quality appraisal checklist, the &#039;Crowe Critical Appraisal Tool&#039; (CCAT) (Crowe, 2013) [1] was applied to the included articles, and effect sizes were calculated when not provided in the papers. 

**RESULTS:**
Methodological quality of the majority of studies included was moderate, with only three studies rated as high quality. Meta-analysis was not conducted as the studies used heterogeneous methodologies and lacked consistency in outcome measures. Limited evidence was found for interventions improving epilepsy knowledge, quality of life, and psychological outcomes. 

**CONCLUSIONS: **
Psychosocial interventions may provide clinical benefit although further research is needed to clarify the most effective treatment components, delivery methods, and measurement of intervention outcomes. The existing evidence base for children and young people is limited by methodological issues such as the use of small samples, inadequate power, and a lack of controlled studies. 

Copyright &copy; 2016 Elsevier Inc. All rights reserved.
AD  - Corrigan, Fiona M. Institute of Mental Health and Wellbeing, University of Glasgow, Glasgow G12 OXH, Scotland, UK. Broome, Helen. Institute of Mental Health and Wellbeing, University of Glasgow, Glasgow G12 OXH, Scotland, UK; Paediatric Neurosciences Research Group, Royal Hospital for Children, Glasgow G51 4TF, Scotland, UK. Dorris, Liam. Institute of Mental Health and Wellbeing, University of Glasgow, Glasgow G12 OXH, Scotland, UK; Paediatric Neurosciences Research Group, Royal Hospital for Children, Glasgow G51 4TF, Scotland, UK. Electronic address: liam.dorris@ggc.scot.nhs.uk.
AN  - 26859319
AU  - Corrigan,
AU  - F.
AU  - M.
AU  - Broome,
AU  - H.
AU  - Dorris,
AU  - L.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.yebeh.2016.01.005
DP  - Ovid Technologies
J2  - Epilepsy Behav
KW  - Child
KW  - Epilepsy/ep [Epidemiology]
KW  - *Epilepsy/px [Psychology]
KW  - *Epilepsy/th [Therapy]
KW  - *Health Knowledge, Attitudes, Practice
KW  - Humans
KW  - Mental Disorders/ep [Epidemiology]
KW  - Mental Disorders/px [Psychology]
KW  - Mental Disorders/th [Therapy]
KW  - Mental Health
KW  - Quality of Life/px [Psychology]
KW  - Self Care/mt [Methods]
KW  - *Self Care/px [Psychology]
KW  - Treatment Outcome
L1  - internal-pdf://3584800521/Corrigan-2016-A systematic review of psychosoc.pdf
LA  - English
M3  - Review
N1  - Corrigan, Fiona M Broome, Helen Dorris, Liam S1525-5050(16)00011-1
PY  - 2016
SP  - 99-112
T2  - Epilepsy &amp; Behavior
TI  - A systematic review of psychosocial interventions for children and young people with epilepsy
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26859319http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26859319&amp;id=doi:10.1016%2Fj.yebeh.2016.01.005&amp;issn=1525-5050&amp;isbn=&amp;volume=56&amp;issue=&amp;spage=99&amp;pages=99-112&amp;date=2016&amp;title=Epilepsy+%26+Behavior&amp;atitle=A+systematic+review+of+psychosocial+interventions+for+children+and+young+people+with+epilepsy.&amp;aulast=Corrigan&amp;pid=%3Cauthor%3ECorrigan+FM%3C%2Fauthor%3E%3CAN%3E26859319%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S1525505016000111/1-s2.0-S1525505016000111-main.pdf?_tid=cdeb0454-04c4-11e7-899e-00000aab0f6b&amp;acdnat=1489063077_c60370aa19b6fe8590462494820da7e0
VL  - 56
ER  -
TY  - JOUR
AB  - Autism spectrum disorders are an emerging health problem worldwide, but little is known about their pathogenesis. 

It has been hypothesized that autism may result from an imbalance between excitatory glutamatergic and inhibitory GABAergic pathways. 

Commonly used medications such as valproate, acamprosate, and arbaclofen may act on the GABAergic system and be a potential treatment for people with ASD. 

The present systematic review aimed at evaluating the state-of-the-art of clinical trials of GABA modulators in autism. 

To date there is insufficient evidence to suggest the use of these drugs in autistic subjects, even if data are promising. 

Of note, short-term use of all the reviewed medications appears to be safe. 

Future well designed trials are needed to elucidate these preliminary findings.
AD  - [Brondino, Natascia; Fusar-Poli, Laura; Panisi, Cristina; Damiani, Stefano; Barale, Francesco; Politi, Pierluigi] Univ Pavia, Dept Brain &amp; Behav Sci, Via Bassi 21, I-27100 Pavia, Italy. Brondino, N (reprint author), Univ Pavia, Dept Brain &amp; Behav Sci, Via Bassi 21, I-27100 Pavia, Italy. natascia.brondino@libero.it
AN  - WOS:000372281600009
AU  - Brondino,
AU  - N.
AU  - Fusar-Poli,
AU  - L.
AU  - Panisi,
AU  - C.
AU  - Damiani,
AU  - S.
AU  - Barale,
AU  - F.
AU  - Politi,
AU  - P.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10803-015-2619-y
J2  - J. Autism Dev. Disord.
KW  - Autism spectrum disorder
KW  - GABA
KW  - Clinical trials
KW  - Systematic review
KW  - pervasive developmental disorders
KW  - messenger-rna levels
KW  - fragile-x-syndrome
KW  - synaptic-transmission
KW  - double-blind
KW  - open-label
KW  - high prevalence
KW  - down-regulation
KW  - children
KW  - receptor
KW  - Psychology
L1  - internal-pdf://1926865074/Brondino-2016-Pharmacological Modulation of GA.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: DG7RO Times Cited: 1 Cited Reference Count: 88 Brondino, Natascia Fusar-Poli, Laura Panisi, Cristina Damiani, Stefano Barale, Francesco Politi, Pierluigi BARALE, FRANCESCO/0000-0001-7820-6736; Politi, Pierluigi/0000-0002-4602-2032 1 9 Springer/plenum publishers New york 1573-3432
PY  - 2016
SP  - 825-839
T2  - Journal of Autism and Developmental Disorders
TI  - Pharmacological Modulation of GABA Function in Autism Spectrum Disorders: A Systematic Review of Human Studies
UR  - &lt;Go to ISI&gt;://WOS:000372281600009
UR  - http://link.springer.com/article/10.1007%2Fs10803-015-2619-y
UR  - http://download.springer.com/static/pdf/45/art%253A10.1007%252Fs10803-015-2619-y.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10803-015-2619-y&amp;token2=exp=1489074274~acl=%2Fstatic%2Fpdf%2F45%2Fart%25253A10.1007%25252Fs10803-015-2619-y.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10803-015-2619-y*~hmac=1e93a7bd3239e4b95df00cb609a3be11fdbcebc754ec68b58351b359bd6c61a7
VL  - 46
ER  -
TY  - JOUR
AB  - The aims of this study were to undertake a meta-analytic and systematic appraisal of the literature investigating the effectiveness of cognitive behavioural therapy (CBT) when used with individuals who have autistic spectrum disorders (ASDs) for either a) affective disorders, orb) the symptoms of ASDs. 

Following a systematic search, 48 studies were included. CBT, used for affective disorders, was associated with a non-significant small to medium effect size, g = 0.24, for self-report measures, a significant medium effect size, g = 0.66, for informant-report measures, and a significant medium effect size, g = 0.73, for clinician-report measures. CBT, used as a treatment for symptoms of ASDs, was associated with a small to medium non-significant effect size, g = 0.25, for self-report measures, a significant small to medium effect size, g = 0.48, for informant-report measures, a significant medium effect size, g = 0.65, for clinician-report measures, and a significant small to medium effect size, g = 035, for task-based measures. 

Sensitivity analyses reduced effect size magnitude, with the exception of that based on informant-report measures for the symptoms of ASDs, which increased, g = 0.52. Definitive trials are needed to demonstrate that CBT is an empirically validated treatment for use with people who have ASDs. 

(C) 2016 The Authors. Published by Elsevier Ltd.
AD  - [Weston, Lisa; Hodgekins, Joanne] Univ East Anglia, Norwich Med Sch, Dept Clin Psychol, Norwich, Norfolk, England. [Langdon, Peter E.] Univ Kent, Tizard Ctr, Canterbury CT2 7LR, Kent, England. [Langdon, Peter E.] Hertfordshire Partnership Univ NHS Fdn Trust Norf, Broadland Clin, Norfolk, VA USA. Langdon, PE (reprint author), Univ Kent, Tizard Ctr, Canterbury CT2 7LR, Kent, England. P.E.Langdon@kent.ac.uk
AN  - WOS:000386743000004
AU  - Weston,
AU  - L.
AU  - Hodgekins,
AU  - J.
AU  - Langdon,
AU  - P.
AU  - E.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2016.08.001
J2  - Clin. Psychol. Rev.
KW  - Autism
KW  - Asperger syndrome
KW  - Pervasive developmental disorder
KW  - Cognitive
KW  - behaviour therapy
KW  - Effectiveness
KW  - Neurodevelopmental disorders
KW  - high-functioning autism
KW  - randomized controlled-trial
KW  - obsessive-compulsive disorder
KW  - social-skills
KW  - asperger-syndrome
KW  - anxiety
KW  - disorders
KW  - training-program
KW  - young-adults
KW  - children
KW  - intervention
KW  - Psychology
L1  - internal-pdf://0293006319/Weston-2016-Effectiveness of cognitive behavio.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: EA6MJ Times Cited: 0 Cited Reference Count: 89 Weston, Lisa Hodgekins, Joanne Langdon, Peter E. Langdon, Peter/0000-0002-7745-1825 National Institute for Health Research Postdoctoral Fellowship [NIHR-PDF-2011-04-040]; National Institute for Health Research (NIHR) Peter E Langdon is supported by a National Institute for Health Research Postdoctoral Fellowship (Grant Reference: NIHR-PDF-2011-04-040). This article presents independent research funded by the National Institute for Health Research (NIHR). The views expressed are those of the author(s) and not necessarily those of the National Health Service, the National Institute for Health Research or the Department of Health. The National Institute for Health Research, the National Health Service, or the Department of Health had no role in the study design, collection, analysis or interpretation of the data, writing the manuscript or the decision to submit the paper for publication. LW and PL initially conceived the design of this study, and JH helped refine the earlier design. LW conducted the searches and analysis. Both PL and LW wrote the initial draft and all authors contributed and approved the final manuscript. All authors declare they have no conflict of interest. 0 18 Pergamon-elsevier science ltd Oxford 1873-7811
PY  - 2016
SP  - 41-54
T2  - Clinical Psychology Review
TI  - Effectiveness of cognitive behavioural therapy with people who have autistic spectrum disorders: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000386743000004
UR  - http://ac.els-cdn.com/S027273581630071X/1-s2.0-S027273581630071X-main.pdf?_tid=17735646-04d2-11e7-9987-00000aab0f02&amp;acdnat=1489068784_e740fcd645d5c41d43b175364aabfc54
VL  - 49
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Youth violence affects thousands annually, with homicide being the third leading cause of death for those aged 10 to 24 years. This systematic review aims to evaluate the published evidence for the effects of health care-based violence intervention programs (VIPs), which focus on reducing recurrent presentations for injury due to youth violence (&quot;recidivism&quot;). 

**METHODS: **
Health literature databases were searched. Studies were retained if peer reviewed and if programs were health care based, focused on intentional injury, addressed secondary or tertiary prevention (i.e., preventing recidivism and reducing complications), included participants aged 14 to 25 years, had greater than 1-month follow-up, and evaluated outcomes. Studies of child and sexual abuse and workplace, intimate partner, and self-inflicted violence were excluded. Extracted data subject to qualitative analysis included enrollment and retention, duration of follow-up, services provided, statistical analysis, and primary and intermediate outcomes. 

**RESULTS: **
Of the 2,144 citations identified, 22 studies were included in the final sample. Twelve studies were randomized controlled trials representing eight VIPs. Injury recidivism was assessed in six (75%) of eight programs with a significant reduction in one (17%) of six programs. Of the randomized controlled trials showing no difference in recidivism, all were either underpowered or did not include a power analysis. Two observational studies also showed significant reduction in recidivism. Significant intermediate outcomes included increased service use, attitude change, and decreases in violence-related behavior. Reductions in injury recidivism led to reductions in health care and criminal justice system costs. 

**CONCLUSIONS: **
Three studies showing reduced injury recidivism and several studies showing positive intermediate outcomes identify VIPs as a promising practice. Many studies were limited by poor methodological quality, including high losses to follow-up. 

**LEVEL OF EVIDENCE: **
Systematic review, level III.
AD  - Strong, Bethany L. From the Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland (B.L.S., W.G.L.); and Health Sciences and Human Services Library, University of Maryland, Baltimore, Maryland (A.G.S., K.D.D.).
AN  - 27537505
AU  - Strong,
AU  - B.
AU  - L.
AU  - Shipper,
AU  - A.
AU  - G.
AU  - Downton,
AU  - K.
AU  - D.
AU  - Lane,
AU  - W.
AU  - G.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/TA.0000000000001222
DP  - Ovid Technologies
J2  - J Trauma Acute Care Surg
L1  - internal-pdf://2727070598/Strong-2016-The effects of health care-based v.pdf
LA  - English
N1  - Strong, Bethany L Shipper, Andrea G Downton, Katherine D Lane, Wendy G
PY  - 2016
SP  - 961-970
T2  - The Journal of Trauma and Acute Care Surgery
TI  - The effects of health care-based violence intervention programs on injury recidivism and costs: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27537505http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27537505&amp;id=doi:10.1097%2FTA.0000000000001222&amp;issn=2163-0755&amp;isbn=&amp;volume=81&amp;issue=5&amp;spage=961&amp;pages=961-970&amp;date=2016&amp;title=The+Journal+of+Trauma+and+Acute+Care+Surgery&amp;atitle=The+effects+of+health+care-based+violence+intervention+programs+on+injury+recidivism+and+costs%3A+A+systematic+review.&amp;aulast=Strong&amp;pid=%3Cauthor%3EStrong+BL%3C%2Fauthor%3E%3CAN%3E27537505%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 81
ER  -
TY  - JOUR
AB  - The Circle of Security (COS) intervention aims to teach caregivers to become more responsive to their children&#039;s needs. The present study is a meta-analysis that examined the efficacy of the COS intervention in relation to child attachment patterns, quality of caregiving, caregiver self-efficacy, and caregiver depression. 

Studies were eligible if they carried out a version of the COS intervention and provided quantitative data amenable to meta-analysis. A total of 10 studies were determined eligible for this meta-analysis. A random effects model was used and Hedge&#039;s g was calculated for the overall effect sizes. 

Results indicated a medium effect size for the efficacy of the intervention for child attachment security (g = 0.65, p = .003, k = 4), quality of caregiving (g = 0.60, p = .012, k = 4) and reduction of caregiver depression (g = 0.53, p &lt; .001, k = 3). There was a significant large effect for improved caregiver self-efficacy (g = 0.98, p &lt; .001, k = 2). 

Results suggest that while the efficacy of the COS intervention demonstrates promising results, more research is needed. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Yaholkoski, Amber: yaholkoa@myumanitoba.ca Yaholkoski, Amber, 284 Rouge Road, Winnipeg, MB, Canada, R3K 1K2, yaholkoa@myumanitoba.ca Yaholkoski, Amber: University of Manitoba, Winnepeg, MB, Canada Hurl, Kylee: Clinical Psychology Program, University of Manitoba, Winnipeg, MB, Canada Theule, Jennifer: Department of Psychology, University of Manitoba, Winnipeg, MB, Canada
AN  - 2016-27739-003
AU  - Yaholkoski,
AU  - A.
AU  - Hurl,
AU  - K.
AU  - Theule,
AU  - J.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/15289168.2016.1163161
DP  - Ovid Technologies
KW  - Circle of Security intervention, caregivers, child attachment, self efficacy, caregiving quality, depression
KW  - *Caregivers
KW  - *Emotional Security
KW  - *Intervention
KW  - *Parent Child Relations
KW  - Attachment Behavior
KW  - Major Depression
KW  - Quality of Care
KW  - Self-Efficacy
KW  - Psychotherapy &amp; Psychotherapeutic Counseling [3310]
KW  - Human Adulthood (18 yrs &amp; older)
L1  - internal-pdf://1084289592/Efficacy of the Circle of Security Interventio.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 95-103
T2  - Journal of Infant, Child and Adolescent Psychotherapy
TI  - Efficacy of the circle of security intervention: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-27739-003http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F15289168.2016.1163161&amp;issn=1528-9168&amp;isbn=&amp;volume=15&amp;issue=2&amp;spage=95&amp;pages=95-103&amp;date=2016&amp;title=Journal+of+Infant%2C+Child+%26+Adolescent+Psychotherapy&amp;atitle=Efficacy+of+the+circle+of+security+intervention%3A+A+meta-analysis.&amp;aulast=Yaholkoski&amp;pid=%3Cauthor%3EYaholkoski%2C+Amber%3C%2Fauthor%3E%3CAN%3E2016-27739-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 15
ER  -
TY  - JOUR
AB  - **Objective: **
Children&#039;s disruptive behavior problems place children at high risk for oppositional defiant disorder and conduct disorder, and carry a high burden for individuals and society. Policy makers and service providers aiming to reduce children&#039;s disruptive behavior problems must often choose between importing an intervention developed abroad or instead developing or using a &quot;home-grown&quot; (i.e., local) intervention. No comprehensive comparison of these interventions exists. 

**Method: **
We performed a multilevel meta-regression of 129 randomized trials (374 effect sizes) of transported and homegrown parenting interventions. We identified trials by searching the included trials lists of systematic reviews, found through searches in 6 databases (e.g., MEDLINE, EMBASE). Trials that had not yet been reviewed were found by searching the same databases. Primary outcome was the mean difference in effectiveness between transported and homegrown interventions to reduce disruptive child behavior. We also compared this differential effectiveness for various intervention &quot;brands&quot; (e.g., Incredible Years and Triple P Positive Parenting Program) and geographical regions (e.g., North America and Europe). 

**Results: **
Transported and homegrown interventions did not differ in their effectiveness to reduce disruptive child behavior (d = 0.10, not significant). Results were robust across intervention brands and geographical regions. Six trials on transported interventions in Hong Kong, Iran, and Panama suggest promising results for transporting interventions to &quot;nonwestern&quot; countries, whereas one trial in Indonesia does not. 

**Conclusion: **
Parenting interventions based on the same principles led to similar outcomes, whether transported or homegrown. This finding supports the selection of interventions based on their evidence base rather than on cultural specificity.
AD  - [Leijten, Patty; Knerr, Wendy; Gardner, Frances] Univ Oxford, Oxford OX1 2ER, England. [Leijten, Patty] Univ Amsterdam, NL-1012 WX Amsterdam, Netherlands. [Melendez-Torres, G. J.] Univ Warwick, Warwick, England. Leijten, P (reprint author), Univ Oxford, Dept Social Policy &amp; Intervent, Ctr Evidence Based Intervent, 32 Wellington Sq, Oxford OX1 2ER, England. patty.leijten@spi.ox.ac.uk
AN  - WOS:000378985200011
AU  - Leijten,
AU  - P.
AU  - Melendez-Torres,
AU  - G.
AU  - J.
AU  - Knerr,
AU  - W.
AU  - Gardner,
AU  - F.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2016.05.003
J2  - J. Am. Acad. Child Adolesc. Psychiatr.
KW  - disruptive behavior problems
KW  - parenting intervention
KW  - randomized
KW  - controlled trial
KW  - multilevel meta-regression
KW  - transportability
KW  - randomized controlled-trial
KW  - conduct problems
KW  - externalizing behaviors
KW  - outcome evaluation
KW  - implementation
KW  - punishment
KW  - families
KW  - programs
KW  - efficacy
KW  - mothers
KW  - Psychology
KW  - Pediatrics
KW  - Psychiatry
L1  - internal-pdf://4005967169/Leijten-2016-Transported Versus Homegrown Pare.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: DQ1UF Times Cited: 0 Cited Reference Count: 49 Leijten, Patty Melendez-Torres, G. J. Knerr, Wendy Gardner, Frances Swedish Board of Health and Welfare This work has been funded with support from the Swedish Board of Health and Welfare (PI Frances Gardner). 0 10 11 Elsevier science inc New york 1527-5418
PY  - 2016
SP  - 610-617
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Transported Versus Homegrown Parenting Interventions for Reducing Disruptive Child Behavior: A Multilevel Meta-Regression Study
UR  - &lt;Go to ISI&gt;://WOS:000378985200011
UR  - http://ac.els-cdn.com/S0890856716301733/1-s2.0-S0890856716301733-main.pdf?_tid=cb48625e-04ca-11e7-810e-00000aacb361&amp;acdnat=1489065649_20bd437d5f9dbb192bd6c9e0e7559f8a
VL  - 55
ER  -
TY  - JOUR
AB  - **Background: **
Perinatal depression is strikingly common with a prevalence of 10-15 %. The adverse effects of perinatal depression on maternal and child health are profound with considerable costs. Despite this, few women seek medical attention. E-health, providing healthcare via the Internet is an accessible and effective solution for the treatment of depression in the general population. We aimed to conduct a systematic review of web-based interventions for the prevention and treatment of mood disorders in the perinatal period, defined as the start of pregnancy to 1 year post-partum. 

**Methods:**
Six databases were searched until 26 March 2015. Two researchers independently screened articles for eligibility. Of the 547 screened articles, four met the inclusion criteria. These included three randomised-controlled trials and one feasibility trial, with total data from 1274 participants. MOOSE and PRISMA guidelines were adhered to for the conduct and reporting of the systematic review. 

**Results:**
All studies were conducted in the post-partum period. All reported an improvement in maternal mood following intervention. A significant improvement in depressive symptoms was measured using validated rating scales, such as the Edinburgh Postnatal Depression Scale (EPDS), either at post-treatment or follow-up which ranged from 3 to 12 months post study completion. For the two RCTs utilising the EPDS, the EPDS score reductions were (mean +/- SEM) 8.52 +/- 0.22 (Range 19.46 to10.94) and 9.19 +/- 0.63 (Range, 20.24 to 11.05) for treatment groups and 5.16 +/- 0.25 (Range 19.44 to 14.28) and 6.81 +/- 0.71 (Range 21.07 to 14.26) for comparator groups. However attrition within studies ranged from 13 to 61 %. One study was rated as &#039;good&#039; quality. 

**Conclusions:** 
Preliminary data suggests web-based therapies for perinatal depression delivered in the post-partum period may play a role in improving maternalmood but more studies are needed, particularly with interventions delivered antenatally. Further research is needed to address the limitations of the existing evidence base. 

Copyright &copy; 2016 Lee et al.
AN  - 608629291
AU  - Lee,
AU  - E.
AU  - W.
AU  - Denison,
AU  - F.
AU  - C.
AU  - Hor,
AU  - K.
AU  - Reynolds,
AU  - R.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/s12884-016-0831-1
L1  - internal-pdf://2139991286/Lee-2016-Web-based interventions for preventio.pdf
PY  - 2016
TI  - Web-based interventions for prevention and treatment of perinatal mood disorders: A systematic review
UR  - http://www.biomedcentral.com/bmcpregnancychildbirth/
VL  - 16 (1) (no pagination)
ER  -
TY  - JOUR
AB  - **Innledning** 
Villet egenskade er en bevisst og villet skade en person påfører seg med eller uten hen‐ sikt å dø. Begrepet inkluderer både selvmordsforsøk og selvskading. Vanlige engelske forkortelser for disse subkategoriene er SA (suicide attempt) og NSSI (non‐suicidal self‐ injury). Ved et selvmordsforsøk har personen et ønske om å dø, selv om ønsket kan være mer eller mindre sterkt. Ved selvskading har personen ikke et ønske om å dø av den aktuelle handlingen (NSSI), men selvskadingen er mer knyttet til å påføre seg selv en fysisk smerte for å endre en intens negativ tanke, følelse eller en vanskelig relasjon. Omfanget av selvskading er usikkert, men ifølge Folkehelseinstituttet kan det være så mange som &eacute;n av ti ungdom som har skadet seg selv. Det er viktig å forebygge ny villet egenskade. I denne kunnskapsoversikten oppsummerer vi effekten av psykososiale sekundærforebyggende tiltak for å forhindre ny selvskading og nye selvmordsforsøk, samt for å redusere psykiatriske symptomer. Kunnskapsoversikten skal først og fremst benyttes til å vurdere behovet for en retningslinje for utredning, oppfølging og behandling av personer med villet egenskade som kommer i kontakt med tjenesteapparatet. Kunnskapsoversikten er videre tenkt å skulle brukes til å planlegge tiltak i form av for eksempel veiledende materiell på nasjonalt nivå. Dessuten er den ment å gi best mulig kunnskapsbaserte innspill til politikere og tjenesteytere om hvordan man kan arbeide med den aktuelle tematikken. 

**Metode** 
En forskningsbibliotekar gjorde et systematisk litteratursøk i september 2015. Vi søkte etter systematiske oversikter med litteratursøk fra 2010 eller senere i databasene Cochrane Database of Systematic Reviews, Center for Reviews and Dissemination, Medline, Embase, Social Sciences/Science Citation Index og Database of Abstracts of Re‐ views of Effects, Cinahl og PsycINFO. Vi søkte også på hjemmesidene til Statens beredning f&ouml;r medicinsk och social utv&auml;rdering (SBU) og Sosialforskningsinstituttet. Vi brukte et filter som er utviklet for å finne referanser til systematiske oversikter. Vi har ikke søkt etter enkeltstudier. To forskere gikk, uavhengig av hverandre, gjennom søke‐ treffene. Dersom minst &eacute;n mente at treffet kunne være relevant, bestilte vi fulltekstartikkelen. De samme to forskerne leste artiklene uavhengig av hverandre og vurderte dem opp mot inklusjonskriteriene. Vi vurderte de systematiske oversiktenes metodiske kvalitet ved hjelp av Kunnskapssenterets sjekkliste. Hvis det var uenighet om kvalitets‐ vurderingen ba vi prosjektansvarlig om å avgjøre. Dersom vi fant flere oversikter med samme problemstilling og av samme kvalitet, inkluderte vi bare den med det nyeste litteratursøket. Vi har ikke vurdert risiko for systematiske feil i enkeltstudier, men gjengir vurderingene til forfatterne av de inkluderte systematiske oversiktene. En forsker (GS) trakk ut data fra de inkluderte oversiktene og en annen forsker (TKD) sjekket tallene. Der hvor de inkluderte systematiske oversiktene har gjort metaanalyser, er disse gjeng‐ itt i vår oversikt. Hvis det ikke var gjort metaanalyser, har vi bare gjengitt resultatene slik de var presentert i de systematiske oversiktene. Vi har brukt Grading of Recommendations Assessment, Development and Evaluation (GRADE) for å vurdere tilliten til resultatene. 

**Resultat** 
Vi har inkludert fire systematiske oversikter fra 2015 som omhandler en lang rekke til‐ tak. Her presenterer vi funnene ordnet etter hvor stor tillit vi har til dem (kvaliteten på dokumentasjonen). Vi har brukt ordet &laquo;trolig&raquo; der resultatet er av middels kvalitet, &laquo;muligens&raquo; der resultatet er av lav kvalitet og &laquo;usikker&raquo; der resultatet er av svært lav kvalitet: Høy kvalitet &oplus;&oplus;&oplus;&oplus; Vi har stor tillit til at effektestimatet ligger nær den sanne effekten. Middels kvalitet &oplus;&oplus;&oplus;⊝ Vi har middels tillit til effektestimatet: Det ligger sannsynligvis nær den sanne effekten, men det er også en mulighet for at den kan være forskjellig. Lav kvalitet &oplus;&oplus;⊝⊝ Vi har begrenset tillit til effektestimatet: Den sanne effekten kan være vesentlig ulik effektestimatet. Svært lav kvalitet &oplus;⊝⊝⊝ Vi har svært liten tillit til at effektestimatet ligger nær den sanne effekten. Middels kvalitet: &bull; Aktiv kontakt og oppfølging fører trolig til færre gjentatte selvmordsforsøk ved 12 måneders oppfølgingstid (RR: 0,83, 95% KI: 0,71 til 0,97). Lav kvalitet: &bull; problemløsningsterapi (OR: 0,71, 95% KI: 0,45 til 1,11) reduserer muligens ny villet egenskade, men konfidensintervallet krysser null effekt. Det er muligens en liten positiv effekt av problemløsningsterapi når det gjelder depresjon (Standardisert gjennomsnittlig forskjell [SMD]: ‐0,36, 95% KI: ‐0,61 til ‐0,11) og håpløshet (vektet gjennomsnittlig forskjell [WMD]: ‐2,97, 95% KI: ‐4,81 til ‐ 1,13). &bull; Psykodynamisk interpersonlig terapi reduserer muligens psykiatriske symptomer (gjennomsnittlig forskjell [MD]: ‐5,0, 95% KI: ‐9,7 til ‐0,3). &bull; Intensiv oppfølging og oppsøking viser litt bedre resultat enn vanlig oppfølging (OR: 0,84, 95% KI: 0,62 til 1,15) når det gjelder ny villet egenskade, men konfidensintervallet krysser null effekt. Tiltaket har muligens ingen eller usikker effekt på nytt selvmordsforsøk etter 18 måneder (OR: 1,02, 95% KI: 0,73 til 1,43), men kan muligens redusere forekomsten av selvmord etter 18 måneder (OR: 0,11, 95% KI: 0,02 til 0,45). Svært lav kvalitet: &bull; Effekten på gjentatt villet egenskade er usikker for kognitiv terapi, kognitiv atferdsterapi, gruppebasert psykoterapi, psykodynamisk interpersonlig terapi, dialektisk atferdsterapi, mentalisering, kontinuerlig oppfølging med samme terapeut (versus bytte av terapeut), &laquo;emergency cards&raquo;, sykehusinnleggelse (versus øyeblikkelig utskrivning), terapeutisk utredning, tiltak for å øke etterlevelse, hjemmebasert familieintervensjon og fjernkontaktintervensjoner. &bull; Effekten på forekomst av nye selvmordsforsøk er usikker for psykoterapi, samt skoleprogrammene C‐CARE og CAST. &bull; Effekten på underliggende psykiatriske symptomer er usikker for kognitiv terapi og psykodynamisk interpersonlig terapi. &bull; Effekten på død av alle årsaker er usikker for aktiv kontakt og oppfølging. &bull; Effekten på nye sykehusinnleggelser er usikker for sykepleieledet &laquo;case management&raquo;. 

**Diskusjon** 
Selv om de inkluderte systematiske oversiktene er av høy kvalitet, har primærstudiene som er inkludert i dem betydelige metodiske svakheter. Studiene er i hovedsak små i den forstand at de har få hendelser (selvmordsforsøk, alvorlig selvskading). Det er behov for randomiserte kontrollerte studier som har så mange deltakere at de oppnår et tilstrekkelig antall hendelser av selvskading og selvmordsforsøk, og det er viktig at den metodiske kvaliteten på studiene forbedres. Vi har ikke vurdert primærstudienes metodiske kvalitet selv. Det er viktig at systematiske oversikter beskriver tiltakene som er gitt godt nok. Det er ikke nok å bare gi merkelapper som for eksempel &laquo;psykodynamisk interpersonlig terapi&raquo;. Det er behov for en detaljert beskrivelse av hva behandlingen gikk ut på, hvem som var behandler, hvor mange behandlingstimer som ble gitt, hvor ofte behandlingen foregikk og hvor lenge. 

**Konklusjon** 
Mange ulike tiltak har vært forsket på, og noen har vist en positiv effekt. Aktiv kontakt og oppfølging etter behandling i akuttmottak reduserer trolig antall nye selvmordsforsøk. Men det er usikkerhet forbundet med disse effektene, og vi vet ikke sikkert om noen tiltak er mer effektive enn andre.
AU  - Smedslund,
AU  - G.
AU  - Dalsbø,
AU  - T.
AU  - K.
AU  - Reinar,
AU  - L.
AU  - M.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/rapport_2016_selvskadingv2.pdf
PY  - 2016
T2  - Folkehelseinstituttet
TI  - Effekter av sekundærforebyggende tiltak mot villet egenskade
ER  -
TY  - JOUR
AB  - **CONTEXT: **
Parenting interventions may prevent adolescent substance use; however, questions remain regarding the effectiveness of interventions across substances and delivery qualities contributing to successful intervention outcomes. 

**OBJECTIVE: **
To describe the effectiveness of parent-focused interventions in reducing or preventing adolescent tobacco, alcohol, and illicit substance use and to identify optimal intervention targeted participants, dosage, settings, and delivery methods. 

**DATA SOURCES: **
PubMed, PsycINFO, ERIC, and CINAHL. 

**STUDY SELECTION:**
Randomized controlled trials reporting adolescent substance use outcomes, focusing on imparting parenting knowledge, skills, practices, or behaviors. 

**DATA EXTRACTION: **
Trained researchers extracted data from each article using a standardized, prepiloted form. Because of study heterogeneity, a qualitative technique known as harvest plots was used to summarize findings. 

**RESULTS: **
A total of 42 studies represented by 66 articles met inclusion criteria. Results indicate that parenting interventions are effective at preventing and decreasing adolescent tobacco, alcohol, and illicit substance use over the short and long term. The majority of effective interventions required &lt;12 contact hours and were implemented through in-person sessions including parents and youth. Evidence for computer-based delivery was strong only for alcohol use prevention. Few interventions were delivered outside of school or home settings. 

**LIMITATIONS: **
Overall risk of bias is high. 

**CONCLUSIONS: **
This review suggests that relatively low-intensity group parenting interventions are effective at reducing or preventing adolescent substance use and that protection may persist for multiple years. There is a need for additional evidence in clinical and other community settings using an expanded set of delivery methods. 

Copyright &copy; 2016 by the American Academy of Pediatrics.
AD  - Allen, Michele L. Departments of Family Medicine and Community Health, and miallen@umn.edu. Garcia-Huidobro, Diego. Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota; School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile; and. Porta, Carolyn. Department of Population Health and Systems, School of Nursing, and. Curran, Dorothy. Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota; Patel, Roma. Departments of Family Medicine and Community Health, and. Miller, Jonathan. Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota. Borowsky, Iris. Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota;
AN  - 27443357
AU  - Allen,
AU  - M.
AU  - L.
AU  - Garcia-Huidobro,
AU  - D.
AU  - Porta,
AU  - C.
AU  - Curran,
AU  - D.
AU  - Patel,
AU  - R.
AU  - Miller,
AU  - J.
AU  - Borowsky,
AU  - I.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1542/peds.2015-4425
DP  - Ovid Technologies
J2  - Pediatrics
L1  - internal-pdf://2750971774/Allen-2016-Effective Parenting Interventions t.pdf
LA  - English
M3  - Review
N1  - Allen, Michele L Garcia-Huidobro, Diego Porta, Carolyn Curran, Dorothy Patel, Roma Miller, Jonathan Borowsky, Iris Using Smart Source Parsing Aug e20154425 peds.2015-4425
PY  - 2016
T2  - Pediatrics
TI  - Effective Parenting Interventions to Reduce Youth Substance Use: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27443357http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27443357&amp;id=doi:10.1542%2Fpeds.2015-4425&amp;issn=0031-4005&amp;isbn=&amp;volume=138&amp;issue=2&amp;spage=e20154425&amp;pages=&amp;date=2016&amp;title=Pediatrics&amp;atitle=Effective+Parenting+Interventions+to+Reduce+Youth+Substance+Use%3A+A+Systematic+Review.&amp;aulast=Allen&amp;pid=%3Cauthor%3EAllen+ML%3C%2Fauthor%3E%3CAN%3E27443357%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 138
ER  -
TY  - JOUR
AB  - This study meta-analytically examined the effect of treatment integrity on client outcomes of evidence-based interventions for juveniles with antisocial behavior. 

A total of 17 studies, from which 91 effect sizes could be retrieved, were included in the present 3-level meta-analysis. All included studies, to a certain level, adequately implemented procedures to establish, assess, evaluate and report the level of treatment integrity. 

A moderator analysis revealed that a medium-to-large effect of evidence-based interventions was found when the level of treatment integrity was high (d = 0.633, p &lt; 0.001), whereas no significant effect was found when integrity was low (d = 0.143, ns). 

Treatment integrity was significantly associated with effect size even when adjusted for other significant moderators, indicating the specific contribution of high levels of treatment integrity to positive client outcomes. 

This implies that delivering interventions with high treatment integrity to youth with antisocial behavior is vital. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AD  - Goense, Pauline Brigitta: p.b.goense@hva.nl; Assink, Mark: M.Assink@uva.nl; Stams, Geert-Jan: G.J.J.M.Stams@uva.nl; Boendermaker, Leonieke: l.boendermaker@hva.nl; Hoeve, Machteld: M.Hoeve@uva.nl Goense, Pauline Brigitta: Implementation and Effectiveness of Youth Care Services Research Group, Faculty of Applied Social Sciences and Law, Amsterdam University of Applied Sciences, Wibautstraat 5a, Amsterdam, Netherlands, 1091 GH, p.b.goense@hva.nl Goense, Pauline Brigitta: Implementation and Effectiveness of Youth Care Services Research Group, Faculty of Applied Social Sciences and Law, Amsterdam University of Applied Sciences, Amsterdam, Netherlands Assink, Mark: Research Institute of Child Development and Education, Faculty of Social and Behavioral Sciences, University of Amsterdam, Amsterdam, Netherlands Stams, Geert-Jan: Research Institute of Child Development and Education, Faculty of Social and Behavioral Sciences, University of Amsterdam, Amsterdam, Netherlands Boendermaker, Leonieke: Implementation and Effectiveness of Youth Care Services Research Group, Faculty of Applied Social Sciences and Law, Amsterdam University of Applied Sciences, Amsterdam, Netherlands Hoeve, Machteld: Research Institute of Child Development and Education, Faculty of Social and Behavioral Sciences, University of Amsterdam, Amsterdam, Netherlands
AN  - 2016-43465-001
AU  - Goense,
AU  - B.
AU  - B.
AU  - Assink,
AU  - M.
AU  - Stams,
AU  - G-J.
AU  - Boendermaker,
AU  - L.
AU  - Hoeve,
AU  - M.
DA  - Nov-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.avb.2016.08.003
DP  - Ovid Technologies
KW  - Treatment integrity, Adherence, Competence, Client outcomes, Evidence-based interventions, Meta-analysis
KW  - *Antisocial Behavior
KW  - *Evidence Based Practice
KW  - *Integrity
KW  - *Juvenile Delinquency
KW  - *Treatment
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human Adolescence (13-17 yrs)
L1  - internal-pdf://3932484501/Goense-2016-Making &#039;what works&#039; work_ A meta-a.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 106-115
T2  - Aggression and Violent Behavior
TI  - Making &#039;what works&#039; work: A meta-analytic study of the effect of treatment integrity on outcomes of evidence-based interventions for juveniles with antisocial behavior
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-43465-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.avb.2016.08.003&amp;issn=1359-1789&amp;isbn=&amp;volume=31&amp;issue=&amp;spage=106&amp;pages=106-115&amp;date=2016&amp;title=Aggression+and+Violent+Behavior&amp;atitle=Making+%27what+works%27+work%3A+A+meta-analytic+study+of+the+effect+of+treatment+integrity+on+outcomes+of+evidence-based+interventions+for+juveniles+with+antisocial+behavior.&amp;aulast=Goense&amp;pid=%3Cauthor%3EGoense%2C+Pauline+Brigitta%3C%2Fauthor%3E%3CAN%3E2016-43465-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S1359178916301021/1-s2.0-S1359178916301021-main.pdf?_tid=57e2e1d4-04c7-11e7-8851-00000aacb362&amp;acdnat=1489064167_27f01291cefbcbef8024c36bc6651956
VL  - 31
ER  -
TY  - JOUR
AB  - **Background:** 
Kangaroo mother care (KMC), originally defined as skin-to-skin contact between a mother and her newborn, frequent and exclusive or nearly exclusive breastfeeding, and early discharge from hospital, has been proposed as an alternative to conventional neonatal care for low birthweight (LBW) infants.

**Objectives:** 
To determine whether evidence is available to support the use of KMC in LBW infants as an alternative to conventional neonatal care before or after the initial period of stabilization with conventional care, and to assess beneficial and adverse effects.

**Search methods:** 
We used the standard search strategy of the Cochrane Neonatal Review Group. This included searches in CENTRAL (Cochrane Central Register of Controlled Trials; 2016, Issue 6), MEDLINE, Embase, CINAHL (Cumulative Index to Nursing and Allied Health Literature), LILACS (Latin American and Caribbean Health Science Information database), and POPLINE (Population Information Online) databases (all from inception to June 30, 2016), as well as the WHO (World Health Organization) Trial Registration Data Set (up to June 30, 2016). In addition, we searched the web page of the Kangaroo Foundation, conference and symposia proceedings on KMC, and Google Scholar.Selection criteria: Randomized controlled trials comparing KMC versus conventional neonatal care, or early-onset KMC versus late-onset KMC, in LBW infants.

**Data collection and analysis:** 
Data collection and analysis were performed according to the methods of the Cochrane Neonatal Review Group.

**Main results:**
Twenty-one studies, including 3042 infants, fulfilled inclusion criteria. Nineteen studies evaluated KMC in LBW infants after stabilization, one evaluated KMC in LBW infants before stabilization, and one compared early-onset KMC with late-onset KMC in relatively stable LBW infants. Sixteen studies evaluated intermittent KMC, and five evaluated continuous KMC. KMC versus conventional neonatal care: At discharge or 40 to 41 weeks&#039; postmenstrual age, KMC was associated with a statistically significant reduction in the risk of mortality (risk ratio [RR] 0.60, 95% confidence interval [CI] 0.39 to 0.92; eight trials, 1736 infants), nosocomial infection/sepsis (RR 0.35, 95% CI 0.22 to 0.54; five trials, 1239 infants), and hypothermia (RR 0.28, 95% CI 0.16 to 0.49; nine trials, 989 infants; moderate-quality evidence). At latest follow-up, KMC was associated with a significantly decreased risk of mortality (RR 0.67, 95% CI 0.48 to 0.95; 12 trials, 2293 infants; moderate-quality evidence) and severe infection/sepsis (RR 0.50, 95% CI 0.36 to 0.69; eight trials, 1463 infants; moderate-quality evidence). Moreover, KMC was found to increase weight gain (mean difference [MD] 4.1 g/d, 95% CI 2.3 to 5.9; 11 trials, 1198 infants; moderate-quality evidence), length gain (MD 0.21 cm/week, 95% CI 0.03 to 0.38; three trials, 377 infants) and head circumference gain (MD 0.14 cm/week, 95% CI 0.06 to 0.22; four trials, 495 infants) at latest follow-up, exclusive breastfeeding at discharge or 40 to 41 weeks&#039; postmenstrual age (RR 1.16, 95% CI 1.07 to 1.25; six studies, 1453 mothers) and at one to three months&#039; follow-up (RR 1.20, 95% CI 1.01 to 1.43; five studies, 600 mothers), any (exclusive or partial) breastfeeding at discharge or at 40 to 41 weeks&#039; postmenstrual age (RR 1.20, 95% CI 1.07 to 1.34; 10 studies, 1696 mothers; moderate-quality evidence) and at one to three months&#039; follow-up (RR 1.17, 95% CI 1.05 to 1.31; nine studies, 1394 mothers; low-quality evidence), and some measures of mother-infant attachment and home environment. No statistically significant differences were found between KMC infants and controls in Griffith quotients for psychomotor development at 12 months? corrected age (low-quality evidence). Sensitivity analysis suggested that inclusion of studies with high risk of bias did not affect the general direction of findings nor the size of the treatment effect for main outcomes. Early-onset KMC versus late-onset KMC in relatively stable infants: One trial compared early-onset continuous KMC (withi 4 hours post birth) versus late-onset continuous KMC (after 24 hours post birth) in 73 relatively stable LBW infants. Investigators reported no significant differences between the two study groups in mortality, morbidity, severe infection, hypothermia, breastfeeding, and nutritional indicators. Early-onset KMC was associated with a statistically significant reduction in length of hospital stay (MD 0.9 days, 95% CI 0.6 to 1.2).

**Authors&#039; conclusions:**
Evidence from this updated review supports the use of KMC in LBW infants as an alternative to conventional neonatal care, mainly in resource-limited settings. Further information is required concerning the effectiveness and safety of early-onset continuous KMC in unstabilized or relatively stabilized LBW infants, as well as long-term neurodevelopmental outcomes and costs of care.
AN  - CD002771
AU  - Conde-Agudelo,
AU  - A.
AU  - D&iacute;az-Rossello,
AU  - J.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd002771.pub4
KW  - Infant Mortality
KW  - Kangaroo-Mother Care Method
KW  - Bacterial Infections [prevention &amp; control]
KW  - Breast Feeding [statistics &amp; numerical data]
KW  - Infant Care [methods]
KW  - Infant, Low Birth Weight [growth &amp; development]
KW  - Infant, Premature, Diseases [mortality] [prevention &amp; control]
KW  - Length of Stay
KW  - Object Attachment
KW  - Physical Stimulation [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Weight Gain
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Infant, Newborn[checkword]
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Kangaroo mother care to reduce morbidity and mortality in low birthweight infants
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002771.pub4/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD002771.pub4/asset/CD002771.pdf?v=1&amp;t=iw7jx7pw&amp;s=e603998e9e33b6c19d2f042ce9d1ba2f9e9c6964
ER  -
TY  - JOUR
AB  - The current study examined the use of video modeling (VM)-based interventions to reduce the challenging behaviors of students with emotional or behavioral disorders. Each study was evaluated using Council for Exceptional Children&#039;s (CEC&#039;s) quality indicators for evidence-based practices. 

In addition, study effects were calculated along the three main categories of VM-based interventions (VM with other as model, video self-modeling, and video-feedback) using a response rate (calculated from visual analysis) and the percentage of non-overlapping data. 

None of the 12 included studies met all the quality indicators set forth by CEC. Overall effects were large for reducing challenging behaviors, though results should be taken with caution due to the small number of studies. Finally, implications for practice and future research are presented.
AD  - [Losinski, Mickey; Wiseman, Nicole; White, Sherry A.; Balluch, Felicity] Kansas State Univ, Manhattan, KS 66506 USA. Losinski, M (reprint author), Kansas State Univ, Special Educ Counseling &amp; Student Affairs, 306 Bluemont Hall, Manhattan, KS 66506 USA. mlosins@ksu.edu
AN  - WOS:000367331300005
AU  - Losinski,
AU  - M.
AU  - Wiseman,
AU  - M.
AU  - White,
AU  - S.
AU  - A.
AU  - Balluch,
AU  - F.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0022466915602493
J2  - J. Spec. Educ.
KW  - video modeling
KW  - emotional or behavioral disorders
KW  - video-feedback
KW  - meta-analysis
KW  - single-case design
KW  - single-subject research
KW  - special-education
KW  - peer interactions
KW  - quantitative synthesis
KW  - classroom-behavior
KW  - self-evaluation
KW  - children
KW  - disorders
KW  - feedback
KW  - autism
KW  - Education &amp; Educational Research
L1  - internal-pdf://1518359556/Losinski.video-modeling.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: CZ8DV Times Cited: 1 Cited Reference Count: 57 Losinski, Mickey Wiseman, Nicole White, Sherry A. Balluch, Felicity 1 2 15 Sage publications inc Thousand oaks 1538-4764
PY  - 2016
SP  - 243-252
T2  - Journal of Special Education
TI  - A Meta-Analysis of Video-Modeling Based Interventions for Reduction of Challenging Behaviors for Students With EBD
UR  - &lt;Go to ISI&gt;://WOS:000367331300005
VL  - 49
ER  -
TY  - JOUR
AB  - **Background:** 
Attention deficit hyperactivity disorder (ADHD) is one of the most common psychiatric conditions affecting children and adolescents. Amphetamines are among the most commonly prescribed medications to manage ADHD. There are three main classes of amphetamines: dexamphetamine, lisdexamphetamine and mixed amphetamine salts, which can be further broken down into short- and long-acting formulations. A systematic review assessing their efficacy and safety in this population has never been conducted.

**Objectives:** 
To assess the efficacy and safety of amphetamines for ADHD in children and adolescents.Search methods: In August 2015 we searched CENTRAL, Ovid MEDLINE, Embase, PsycINFO, ProQuest Dissertation and Theses, and the Networked Digital Library of Theses and Dissertations. We also searched ClinicalTrials.gov, and checked the reference lists of relevant studies and reviews identified by the searches. No language or date restrictions were applied.Selection criteria: Parallel-group and cross-over randomized controlled trials (RCTs) comparing amphetamine derivatives against placebo in a pediatric population (&lt; 18 years) with ADHD.

**Data collection and analysis:** 
Two authors independently extracted data on participants, settings, interventions, methodology, and outcomes for each included study. For continuous outcomes, we calculated the standardized mean difference (SMD) and for dichotomous outcomes we calculated the risk ratio (RR). Where possible, we conducted meta-analyses using a random-effects model. We also performed a meta-analysis of the most commonly reported adverse events in the primary studies.

**Main results:** 
We included 23 trials (8 parallel-group and 15 cross-over trials), with 2675 children aged three years to 17 years. All studies compared amphetamines to placebo. Study durations ranged from 14 days to 365 days, with the majority lasting less than six months. Most studies were conducted in the United States; three studies were conducted across Europe. We judged 11 included studies to be at a high risk of bias due to insufficient blinding methods, failing to account for dropouts and exclusions from the analysis, and failing to report on all outcomes defined a priori. We judged the remaining 12 studies to be at unclear risk of bias due to inadequate reporting.Amphetamines improved total ADHD core symptom severity according to parent ratings (SMD -0.57; 95% confidence interval (CI) -0.86 to -0.27; 7 studies; 1247 children/adolescents; very low quality evidence), teacher ratings (SMD -0.55; 95% CI -0.83 to -0.27; 5 studies; 745 children/adolescents; low quality evidence), and clinician ratings (SMD -0.84; 95% CI -1.32 to -0.36; 3 studies; 813 children/adolescents; very low quality evidence). In addition, the proportion of responders as rated by the Clinical Global Impression - Improvement (CGI-I) scale was higher when children were taking amphetamines (RR 3.36; 95% CI 2.48 to 4.55; 9 studies; 2207 children/adolescents; very low quality evidence).The most commonly reported adverse events included decreased appetite, insomnia/trouble sleeping, abdominal pain, nausea/vomiting, headaches, and anxiety. Amphetamines were associated with a higher proportion of participants experiencing decreased appetite (RR 6.31; 95% CI 2.58 to 15.46; 11 studies; 2467 children/adolescents), insomnia (RR 3.80; 95% CI 2.12 to 6.83; 10 studies; 2429 children/adolescents), and abdominal pain (RR 1.44; 95% CI 1.03 to 2.00; 10 studies; 2155 children/adolescents). In addition, the proportion of children who experienced at least one adverse event was higher in the amphetamine group (RR 1.30; 95% CI 1.18 to 1.44; 6 studies; 1742 children/adolescents; low quality evidence). We performed subgroup analyses for amphetamine preparation (dexamphetamine, lisdexamphetamine, mixed amphetamine salts), amphetamine release formulation (long acting versus short acting), and funding source (industry versus non industry). Between-group differences were observed for proportion of participants experiencing decreased appetite in both the amphetamine preparat o (P &lt; 0.00001) and amphetamine release formulation (P value = 0.008) subgroups, as well as for retention in the amphetamine release formulation subgroup (P value = 0.03).

**Authors&#039; conclusions:** 
Most of the included studies were at high risk of bias and the overall quality of the evidence ranged from low to very low on most outcomes. Although amphetamines seem efficacious at reducing the core symptoms of ADHD in the short term, they were associated with a number of adverse events. This review found no evidence that supports any one amphetamine derivative over another, and does not reveal any differences between long-acting and short-acting amphetamine preparations. Future trials should be longer in duration (i.e. more than 12 months), include more psychosocial outcomes (e.g. quality of life and parent stress), and be transparently reported.
AN  - CD009996
AU  - Punja,
AU  - S.
AU  - Shamseer,
AU  - L.
AU  - Hartling,
AU  - L.
AU  - Urichuk,
AU  - L.
AU  - Vandermeer,
AU  - B.
AU  - Nikles,
AU  - J.
AU  - Vohra,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009996.pub2.
KW  - Amphetamines [therapeutic use]
KW  - Attention Deficit Disorder with Hyperactivity [drug therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
L1  - internal-pdf://2567297279/Punja_et_al-2016-The_Cochrane_Library.pdf
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Amphetamines for attention deficit hyperactivity disorder (ADHD) in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009996.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009996.pub2/asset/CD009996.pdf?v=1&amp;t=iw7inhjf&amp;s=b4b62c9b665251918cd8598ffd48e20316f61e1f
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To examine the effectiveness of Audiovisual (AV) interventions at reducing preoperative anxiety and its associated outcomes in children undergoing elective surgery. 

**METHODS: **
A systematic review of randomized controlled trials (RCTs) and nonrandomized studies where the primary outcome was children&#039;s preoperative anxiety was conducted. Secondary outcomes included postoperative pain, behavioral changes, recovery, induction compliance, satisfaction, and cost-effectiveness. The risk of bias of each study was assessed.

**RESULTS: **
In all, 18 studies were identified. A meta-analytic approach and narrative synthesis of findings were used to summarize the results of the studies. 

**CONCLUSIONS: **
This systematic review suggests that AV interventions can be effective in reducing children&#039;s preoperative anxiety. Videos, multi-faceted programs, and interactive games appear to be most effective, whereas music therapy and Internet programs are less effective. While AV interventions appear potentially useful, adequately powered RCTs are required to conclusively pinpoint the components and mechanisms of the most effective AV interventions and guide practice. 

Copyright &copy; The Author 2015. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. 
All rights reserved. 
For permissions, please e-mail: journals.permissions@oup.com.
AD  - Chow, Cheryl H T. MiNDS Neuroscience Graduate Program, chowcht@mcmaster.ca. Van Lieshout, Ryan J. MiNDS Neuroscience Graduate Program, Department of Psychiatry &amp; Behavioral Neurosciences. Schmidt, Louis A. MiNDS Neuroscience Graduate Program, Department of Psychology, Neuroscience &amp; Behavior. Dobson, Kathleen G. Department of Clinical Epidemiology &amp; Biostatistics, and. Buckley, Norman. Department of Anesthesia, McMaster University, Ontario, Canada.
AN  - 26476281
AU  - Chow,
AU  - C.
AU  - H.
AU  - Van
AU  - Lieshout,
AU  - R.
AU  - J.
AU  - Schmidt,
AU  - L.
AU  - A.
AU  - Dobson,
AU  - K.
AU  - G.
AU  - Buckley,
AU  - N.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1093/jpepsy/jsv094
DP  - Ovid Technologies
J2  - J Pediatr Psychol
KW  - *Anxiety/pc [Prevention &amp; Control]
KW  - *Anxiety/px [Psychology]
KW  - Attention
KW  - *Audiovisual Aids
KW  - Child
KW  - Child, Preschool
KW  - *Elective Surgical Procedures/px [Psychology]
KW  - Female
KW  - Humans
KW  - Internet
KW  - Male
KW  - Music Therapy
KW  - Play and Playthings
KW  - *Preoperative Care/mt [Methods]
KW  - *Preoperative Care/px [Psychology]
KW  - *Preoperative Period
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://0194031214/Chow-2016-Systematic Review_ Audiovisual Inter.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Chow, Cheryl H T Van Lieshout, Ryan J Schmidt, Louis A Dobson, Kathleen G Buckley, Norman jsv094
PY  - 2016
SP  - 182-203
T2  - Journal of Pediatric Psychology
TI  - Systematic Review: Audiovisual Interventions for Reducing Preoperative Anxiety in Children Undergoing Elective Surgery
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26476281http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26476281&amp;id=doi:10.1093%2Fjpepsy%2Fjsv094&amp;issn=0146-8693&amp;isbn=&amp;volume=41&amp;issue=2&amp;spage=182&amp;pages=182-203&amp;date=2016&amp;title=Journal+of+Pediatric+Psychology&amp;atitle=Systematic+Review%3A+Audiovisual+Interventions+for+Reducing+Preoperative+Anxiety+in+Children+Undergoing+Elective+Surgery.&amp;aulast=Chow&amp;pid=%3Cauthor%3EChow+CH%3C%2Fauthor%3E%3CAN%3E26476281%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884908/pdf/jsv094.pdf
VL  - 41
ER  -
TY  - JOUR
AB  - This article reports on the results of a systematic review and meta-analysis of the effects of after-school programs (ASPs) on delinquency. Mixed results from some well-known evaluations, a wide range of modalities, and continued interest in and demand for this social intervention motivated this review. 

A rigorous criteria for inclusion of studies was developed, comprehensive search strategies were employed to identify eligible studies (published and unpublished), and a protocol was followed for coding of key study features. Meta-analytic techniques were used to assess the impact of ASPs on delinquency and investigate study features associated with variation in effects. Seventeen studies-based on 17 independent samples-met the inclusion criteria. 

All but two of the studies were multimodal, involving primary and secondary interventions. Studies could be grouped into one of the three primary intervention types: academic, recreation, and skills training/mentoring. There was evidence that ASPs had a small but nonsignificant effect on delinquency, with a weighted mean d = 0.062 (95% confidence interval: -0.098, 0.223). Moderator analyses indicated that not one of the intervention types was associated with a significant effect on delinquency. Nothing in the present review suggests that ASPs-of any type-should be discontinued. 

But business as usual does not seem in order for ASPs with a focus on delinquency prevention. Several research priorities could go some way toward addressing this, including further high-quality evaluations targeted on the three main types of ASPs and a special focus on program fidelity. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Welsh, Brandon C.: b.welsh@neu.edu Welsh, Brandon C.: School of Criminology and Criminal Justice, Northeastern University, Churchill Hall, 360 Huntington Avenue, Boston, MA, US, 02115, b.welsh@neu.edu Taheri, Sema A.: Northeastern University, Boston, MA, US Welsh, Brandon C.: Northeastern University, Boston, MA, US
AN  - 2016-25421-006
AU  - Taheri,
AU  - S.
AU  - A.
AU  - Welsh,
AU  - B.
AU  - C.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - DOI 10.1007/s10803-016-2854-x
DP  - Ovid Technologies
KW  - after-school program, delinquency prevention, systematic review, meta-analysis
KW  - *After School Programs
KW  - *Juvenile Delinquency
KW  - Curriculum &amp; Programs &amp; Teaching Methods [3530]
KW  - Human Adolescence (13-17 yrs)
L1  - internal-pdf://0572378959/AfterSchoolProgramsforDeliquencyPrevention.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 272-290
T2  - Youth Violence and Juvenile Justice
TI  - After-school programs for delinquency prevention: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-25421-006http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1541204014567542&amp;issn=1541-2040&amp;isbn=&amp;volume=14&amp;issue=3&amp;spage=272&amp;pages=272-290&amp;date=2016&amp;title=Youth+Violence+and+Juvenile+Justice&amp;atitle=After-school+programs+for+delinquency+prevention%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Taheri&amp;pid=%3Cauthor%3ETaheri%2C+Sema+A%3C%2Fauthor%3E%3CAN%3E2016-25421-006%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 14
ER  -
TY  - JOUR
AB  - Youths exposed to armed conflict have a higher prevalence of mental health and psychosocial difficulties. Diverse interventions exist that aim to ameliorate the effect of armed conflict on the psychological and psychosocial wellbeing of conflict affected youths. However, the evidence base for the effectiveness of these interventions is limited. 

Using standard review methodology, this review aims to address the effectiveness of psychological interventions employed among this population. The search was performed across four databases and grey literature. Article quality was assessed using the Downs and Black Quality Checklist (1998). Where possible, studies were subjected to meta-analyses. 

The remaining studies were included in a narrative synthesis. Eight studies concerned non clinical populations, while nine concerned clinical populations. Review findings conclude that Group Trauma Focused-Cognitive Behavioural Therapy is effective for reducing symptoms of posttraumatic stress disorder, anxiety, depression and improving prosocial behaviour among clinical cohorts. 

The evidence does not suggest that interventions aimed at non clinical groups within this population are effective. Despite high quality studies, further robust trials are required to strengthen the evidence base, as a lack of replication has resulted in a limited evidence base to inform practice. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-03274-007
AU  - O&#039;Sullivan,
AU  - C.
AU  - Bosqui,
AU  - T.
AU  - Shannon,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/WTF.0000000000000110
L1  - internal-pdf://2233567350/O&#039;Sullivan-2016-Psychological interventions fo.pdf
PY  - 2016
SP  - 142-164
TI  - Psychological interventions for children and young people affected by armed conflict or political violence: A systematic literature review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-03274-007
VL  - 14
ER  -
TY  - JOUR
AB  - The effectiveness of different types of CBT for children and adolescents suffering from Social Anxiety Disorder (SAD) is generally supported. 

However, no systematic efforts have been made to quantitatively summarize and analyse the impact of specific variables on therapeutic outcome. Here, we assessed the magnitude and duration of CBT effectiveness in children and adolescents with SAD. 

The effectiveness of CBT was supported by the effect sizes of studies that had examined pre-post (g = 0.99), between-group (g = 0.71), and follow-up responses (follow-up vs. pre-test mean g = 1.18, follow-up vs. post-test mean g = 0.25). 

A significant moderating effect was found for the variable &quot;number of treatment sessions&quot;. In addition, larger effect sizes were found in studies that included &quot;Social Skills Training&quot; sessions in the intervention package. 

Data support the effectiveness of CBT interventions and its durability for SAD in children and adolescents. Adding social skills training to the intervention package can further enhance the impact of treatment. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2016-43063-013
AU  - Scaini,
AU  - S.
AU  - Belotti,
AU  - R.
AU  - Ogliari,
AU  - A.
AU  - Battaglia,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.janxdis.2016.05.008
L1  - internal-pdf://4074126457/Scaini-2016-A comprehensive meta-analysis of c.pdf
PY  - 2016
SP  - 105-112
TI  - A comprehensive meta-analysis of cognitive-behavioral interventions for social anxiety disorder in children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-43063-013
VL  - 42
ER  -
TY  - JOUR
AB  - A systematic review of published and unpublished English language articles identified 14 studies containing 18 comparisons between functional family therapy (FFT) and another condition in the treatment of adolescent disruptive behavior and substance use disorders. In 11 of these comparisons, assignment to conditions was random, while nonrandom assignment occurred in seven studies. 

For both random and nonrandom comparisons, separate meta-analyses were conducted for subgroups of studies depending on the type of comparison group used. Data from studies of untreated control groups (CTL), treatment as usual (TAU), and well-defined alternative treatments (ALTs) were analyzed separately. 

Effect sizes from these six meta-analyses were as follows: random assignment FFT versus CTL (k = 3, d = 0.48, p &lt; .01); random assignment FFT versus TAU (k = 3, d = .20, ns); random assignment FFT versus ALT (k = 5, d = .35, p &lt; .05); nonrandom assignment FFT versus CTL (k = 2, d = .90, ns); nonrandom assignment FFT versus TAU (k = 2, d = .08, ns); and nonrandom assignment FFT versus ALT (k = 3, d = .75, p &lt; .001). 

These results provide support for the effectiveness of FFT compared with untreated controls and well-defined ALTs, such as cognitive behavior therapy, other models of family therapy, and individual and group therapy for adolescents. 

Copyright &copy; 2016 Family Process Institute.
AD  - Hartnett, Dan. School of Psychology, University College Dublin, Dublin, Ireland. daniel.hartnett@ucdconnect.ie. Carr, Alan. School of Psychology, University College Dublin, Dublin, Ireland. Hamilton, Elena. School of Psychology, University College Dublin, Dublin, Ireland. O&#039;Reilly, Gary. School of Psychology, University College Dublin, Dublin, Ireland.
AN  - 27731494
AU  - Hartnett,
AU  - D.
AU  - Carr,
AU  - A.
AU  - Hamilton,
AU  - E.
AU  - O&#039;Reilly,
AU  - G.
DA  - Oct 12
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/famp.12256
DP  - Ovid Technologies
J2  - Fam Process
L1  - internal-pdf://2173892946/Hartnett_et_al-2016-Family_Process.pdf
LA  - English
N1  - Hartnett, Dan Carr, Alan Hamilton, Elena O&#039;Reilly, Gary Using Smart Source Parsing Oct
PY  - 2016
SP  - 12
T2  - Family Process
TI  - The Effectiveness of Functional Family Therapy for Adolescent Behavioral and Substance Misuse Problems: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=27731494http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27731494&amp;id=doi:10.1111%2Ffamp.12256&amp;issn=0014-7370&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2016&amp;title=Family+Process&amp;atitle=The+Effectiveness+of+Functional+Family+Therapy+for+Adolescent+Behavioral+and+Substance+Misuse+Problems%3A+A+Meta-Analysis.&amp;aulast=Hartnett&amp;pid=%3Cauthor%3EHartnett+D%3C%2Fauthor%3E%3CAN%3E27731494%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 12
ER  -
TY  - JOUR
AB  - The objective of this study was to evaluate the current state of evidence of the effectiveness of depression prevention programs for youth, assess the degree to which current evidence supports broad implementation, and outline additional steps needed to close the gap between effectiveness and dissemination. 

We used the Society for Prevention Research&#039;s Standards of Evidence (Flay et al., 2005 ) to evaluate the degree to which existing depression prevention programs have established intervention efficacy, effectiveness, and readiness for dissemination. We reviewed all depression prevention programs for youth that have been evaluated in at least two published, randomized controlled trials in which the intervention was compared to a no-intervention control group. 

A total of 37 studies evaluating 11 different programs were reviewed with regard to depressive symptoms and diagnoses at postintervention and follow-up (at least 6 months). Eight programs demonstrated significant main effects on depressive symptoms relative to controls in multiple randomized controlled trials; 5 programs had at least 1 trial with significant main effects present at least 1 year postintervention. Two programs demonstrated efficacy for both depressive symptoms and depressive episodes across multiple independent trials. 

Regarding effectiveness, 6 programs had at least 1 study showing significant effects when delivered by endogenous service providers; 4 programs had significant effects in studies conducted independently of the program developers. Several programs have demonstrated promise in terms of efficacy, but no depression prevention program for children or adolescents as yet has garnered sufficient evidence of effectiveness under real-world conditions to warrant widespread dissemination at this time.
AN  - 25933173
AU  - Brunwasser,
AU  - S.
AU  - M.
AU  - Garber,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
L1  - internal-pdf://3299415744/Brunwasser-2016-Programs for the Prevention of.pdf
PY  - 2016
SP  - 763-783
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Programs for the Prevention of Youth Depression: Evaluation of Efficacy, Effectiveness, and Readiness for Dissemination
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=25933173
VL  - 45
ER  -
TY  - JOUR
AB  - **BACKGROUND AND AIMS: **
Peer-led interventions may offer a beneficial approach in preventing substance use, but their impact has not yet been quantified. We conducted a systematic review to investigate and quantify the effect of peer-led interventions that sought to prevent tobacco, alcohol and/or drug use among young people aged 11-21 years. 

**METHODS: **
Medline, EMBASE, PsycINFO, CINAHL, ERIC and the Cochrane Library were searched from inception to July 2015 without language restriction. We included randomized controlled trials only. Screening and data extraction were conducted in duplicate and data from eligible studies were pooled in a random effects meta-analysis. 

**RESULTS: **
We identified 17 eligible studies, approximately half of which were school-based studies targeting tobacco use among adolescents. Ten studies targeting tobacco use could be pooled, representing 13,706 young people in 220 schools. Meta-analysis demonstrated that the odds of smoking were lower among those receiving the peer-led intervention compared with control [odds ratio (OR) = 0.78, 95% confidence interval (CI) = 0.62-0.99, P = 0.040]. There was evidence of heterogeneity (I(2) = 41%, chi(2) 15.17, P = 0.086). Pooling of six studies representing 1699 individuals in 66 schools demonstrated that peer-led interventions were also associated with benefit in relation to alcohol use (OR = 0.80, 95% CI = 0.65-0.99, P = 0.036), while three studies (n = 976 students in 38 schools) suggested an association with lower odds of cannabis use (OR = 0.70, 0.50-0.97, P = 0.034). No studies were found that targeted other illicit drug use. 

**CONCLUSIONS:**
Peer interventions may be effective in preventing tobacco, alcohol and possibly cannabis use among adolescents, although the evidence base is limited overall, and is characterized mainly by small studies of low quality. 

Copyright &copy; 2015 Society for the Study of Addiction.
AD  - Georgie J, MacArthur. School of Social and Community Medicine, University of Bristol, Bristol, UK. Sean, Harrison. School of Social and Community Medicine, University of Bristol, Bristol, UK. Deborah M, Caldwell. School of Social and Community Medicine, University of Bristol, Bristol, UK. Matthew, Hickman. School of Social and Community Medicine, University of Bristol, Bristol, UK. Rona, Campbell. School of Social and Community Medicine, University of Bristol, Bristol, UK.
AN  - 26518976
AU  - Georgie,
AU  - J.
AU  - M.
AU  - Sean,
AU  - H.
AU  - Deborah,
AU  - M.
AU  - C.
AU  - Matthew,
AU  - H.
AU  - Rona,
AU  - C.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/add.13224
DP  - Ovid Technologies
J2  - Addiction
KW  - Adolescent
KW  - *Alcohol Drinking/pc [Prevention &amp; Control]
KW  - Child
KW  - Humans
KW  - *Marijuana Smoking/pc [Prevention &amp; Control]
KW  - Odds Ratio
KW  - *Peer Group
KW  - Randomized Controlled Trials as Topic
KW  - School Health Services
KW  - *Smoking/pc [Prevention &amp; Control]
KW  - *Substance-Related Disorders/pc [Prevention &amp; Control]
KW  - Tobacco Use Disorder/pc [Prevention &amp; Control]
KW  - Underage Drinking/pc [Prevention &amp; Control]
KW  - Young Adult
L1  - internal-pdf://0980742311/Georgie-2016-Peer-led interventions to prevent.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Georgie J, MacArthur Sean, Harrison Deborah M, Caldwell Matthew, Hickman Rona, Campbell
PY  - 2016
SP  - 391-407
T2  - Addiction
TI  - Peer-led interventions to prevent tobacco, alcohol and/or drug use among young people aged 11-21 years: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26518976http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26518976&amp;id=doi:10.1111%2Fadd.13224&amp;issn=0965-2140&amp;isbn=&amp;volume=111&amp;issue=3&amp;spage=391&amp;pages=391-407&amp;date=2016&amp;title=Addiction&amp;atitle=Peer-led+interventions+to+prevent+tobacco%2C+alcohol+and%2For+drug+use+among+young+people+aged+11-21+years%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Georgie+J&amp;pid=%3Cauthor%3EGeorgie+J+M%3C%2Fauthor%3E%3CAN%3E26518976%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1111/add.13224/asset/add13224.pdf?v=1&amp;t=j02e78xl&amp;s=773a939bb467d272a07bfbbb701592268c11d878
VL  - 111
ER  -
TY  - JOUR
AB  - **Background and objective **
Long-chain polyunsaturated fatty acids, especially docosahexaenoic acid, have been suggested as a nutrition factor affecting visual and neurobehavioral development of preterm infants. Several randomized controlled trials (RCTs) have investigated the effect of supplementation of long-chain polyunsaturated fatty acids on preterm infants. We conducted a systematic review and meta-analysis to examine the efficacy of long-chain polyunsaturated fatty acid supplementation of formula or breast milk on the neurodevelopment outcomes of preterm infants. 

**Methods**
Two authors searched PubMed and Cochrane Library (CENTRAL) for RCTs assessing efficacy of long-chain polyunsaturated fatty acids supplementation on the neurobehavioral and development outcomes of preterm infant. Human RCTs which supplemented long-chain polyunsaturated fatty acids during lactation and assessed neurodevelopment were included. The quality of each RCT was assessed, and the results of eligible trials were included in the systematic review and meta-analysis. 

**Results **
We included 11 RCTs with 2272 total participants. Methodologic limitations existed to some extent in most RCTs that were included. Because the age of the participants from different trails was not the same, different scales and indexes had been assessed from different RCTs. Our meta-analysis indicated a significant effect of long-chain polyunsaturated fatty acids supplementation on the neurodevelopment of preterm infants assessed by the Mental Development Index of the Bayley Scales at one to three years of age versus the control groups. 

**Conclusion **
Analysis of our consolidated data indicates that long-chain fatty acid supplementation results in a significant improvement in the neurodevelopment of preterm infants as assessed by the Mental Development Index at one to three years of age. The available evidence suggests that long-chain polyunsaturated fatty acid supplementation during lactation may accelerate the pace of neurodevelopment in preterm infants, although their final developmental outcome may be unchanged. 

Copyright &copy; 2016 Elsevier Inc.
AD  - (Wang, Cui, Yan) Department of Pediatrics, Third Affiliated Hospital, Guangzhou Medical University, 63 Duobao Road, Liwan District; Guangzhou, Guangdong, China Q. Cui, Department of Pediatrics, Third Affiliated Hospital, Guangzhou Medical University, 63 Duobao Road, Liwan District; Guangzhou, Guangdong, China. E-mail: gycuiqiliang@126.com
AN  - 610815690
AU  - Wang,
AU  - Q.
AU  - Cui,
AU  - Q.
AU  - Yan,
AU  - C.
DA  - 01 Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.pediatrneurol.2016.02.017
DP  - Ovid Technologies
KW  - Long chain polyunsaturated fatty acids
KW  - Meta-analysis
KW  - Neurodevelopmental outcome
KW  - Preterm
KW  - RCTs
KW  - article
KW  - artificial milk
KW  - Bayley Scales of Infant Development
KW  - breast milk
KW  - clinical effectiveness
KW  - human
KW  - infancy
KW  - infant
KW  - lactation
KW  - meta analysis
KW  - nervous system development
KW  - outcome assessment
KW  - prematurity
KW  - priority journal
KW  - randomized controlled trial (topic)
KW  - supplementation
KW  - systematic review
KW  - long chain fatty acid
KW  - polyunsaturated fatty acid
KW  - child
KW  - Cochrane Library
KW  - comparative effectiveness
KW  - control group
KW  - controlled clinical trial
KW  - controlled study
KW  - Medline
KW  - mental development
KW  - randomized controlled trial
L1  - internal-pdf://1716446161/Wang-2016-The Effect of Supplementation of Lon.pdf
LA  - English
PY  - 2016
SP  - 54-61
T2  - Pediatric Neurology
TI  - The Effect of Supplementation of Long-Chain Polyunsaturated Fatty Acids during Lactation on Neurodevelopmental Outcomes of Preterm Infant from Infancy to School Age: A Systematic Review and Meta-analysis
UR  - http://www.elsevier.com/locate/pedneuhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18a&amp;AN=610815690http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.pediatrneurol.2016.02.017&amp;issn=0887-8994&amp;isbn=&amp;volume=59&amp;issue=&amp;spage=54&amp;pages=54-61&amp;date=2016&amp;title=Pediatric+Neurology&amp;atitle=The+Effect+of+Supplementation+of+Long-Chain+Polyunsaturated+Fatty+Acids+during+Lactation+on+Neurodevelopmental+Outcomes+of+Preterm+Infant+from+Infancy+to+School+Age%3A+A+Systematic+Review+and+Meta-analysis&amp;aulast=Wang&amp;pid=%3Cauthor%3EWang+Q.%3C%2Fauthor%3E%3CAN%3E610815690%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0887899415301004/1-s2.0-S0887899415301004-main.pdf?_tid=b845e030-04d1-11e7-9d23-00000aab0f26&amp;acdnat=1489068624_9d5455070be9a1b4cf4eec5fbcde09e6
VL  - 59
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
At least 30% of young people with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) also have symptoms of depression. This systematic review aimed to establish which treatment approaches for depression are effective and whether comorbid depression mediates outcome. 

**SETTING: **
A systematic review was undertaken. The search terms were entered into MEDLINE, EMBASE, PsycInfo and the Cochrane library. 

**PARTICIPANTS: **
Inclusion and exclusion criteria were applied to identify relevant papers. Inclusion criteria were children age &lt;18, with CFS/ME, defined using CDC, NICE or Oxford criteria, and having completed a valid assessment for depression. 

**RESULTS: **
9 studies were identified which met the inclusion criteria, but none specifically tested treatments for paediatric CFS/ME with depression and none stratified outcome for those who were depressed compared with those who were not depressed. There is no consistent treatment approach for children with CFS/ME and comorbid depression, although cognitive-behavioural therapy for CFS/ME and a multicomponent inpatient programme for CFS/ME have shown some promise in reducing depressive symptoms. An antiviral medication in a small scale, retrospective, uncontrolled study suggested possible benefit. 

**CONCLUSIONS: **
It is not possible to determine what treatment approaches are effective for depression in paediatric CFS/ME, nor to determine the impact of depression on the outcome of CFS/ME treatment. Young people with significant depression tend to have been excluded from previous treatment studies. 

Copyright Published by the BMJ Publishing Group Limited. 
For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
AD  - Loades, Maria E. Department of Psychology, University of Bath, Bath, UK. Sheils, Elizabeth A. Department of Psychology, University of Bath, Bath, UK. Crawley, Esther. School of Social and Community Medicine, University of Bristol, Bristol, UK.
AN  - 27729349
AU  - Loades,
AU  - M.
AU  - E.
AU  - Sheils,
AU  - E.
AU  - A.
AU  - Crawley,
AU  - E.
DA  - Oct 11
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1136/ bmjopen-2016-012271
DP  - Ovid Technologies
J2  - BMJ Open
L1  - internal-pdf://1798327973/Loades-2016-Treatment for paediatric chronic f.pdf
LA  - English
N1  - Loades, Maria E Sheils, Elizabeth A Crawley, Esther bmjopen-2016-012271
PY  - 2016
SP  - e012271
T2  - BMJ Open
TI  - Treatment for paediatric chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) and comorbid depression: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27729349http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27729349&amp;id=doi:10.1136%2Fbmjopen-2016-012271&amp;issn=2044-6055&amp;isbn=&amp;volume=6&amp;issue=10&amp;spage=e012271&amp;pages=e012271&amp;date=2016&amp;title=BMJ+Open&amp;atitle=Treatment+for+paediatric+chronic+fatigue+syndrome+or+myalgic+encephalomyelitis+%28CFS%2FME%29+and+comorbid+depression%3A+a+systematic+review.&amp;aulast=Loades&amp;pid=%3Cauthor%3ELoades+ME%3C%2Fauthor%3E%3CAN%3E27729349%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073581/pdf/bmjopen-2016-012271.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The aim of this study was to directly compare efficacy of atomoxetine and methylphenidate in treatment of children and adolescents 6- 18 years. 

**METHODS: **
All published, randomized, open label or double blind trials, comparing the efficacy of methylphenidate with atomoxetine in treatment of children diagnosed with ADHD, using DSM-IV criteria were included in this study; ADHD Rating Scale-IV-Parent Version: Investigator Administered and Scored (ADHDRS) scores was used. The standardized mean difference (SMD) was used as a measure of effect size. 

**RESULTS: **
Eleven studies were included with a total of 2,772 participants. The meta-analysis did not find a significant difference in the efficacy between methylphenidate and atomoxetine (SMD= 0.09, 95% CI -0.06, 0.25) (Z= 1.18, p= 0.24). Sub group analysis showed a significant standardized mean difference favoring OROS methylphenidate (SMD= 0.31, 95% CI 0.16, 0.47 (Z= 3.91, p&lt; 0.0001); immediate release methylphenidate was not superior to atomoxetine (SMD= -0.05, 95% CI -0.20, 0.10) (Z= 0.68, p= 0.49). Open label trials did not make a difference in the standardized mean difference (SMD= 0.10, 95% CI -0.02, 0.23) (Z= 1.17, p= 0.09). There was significant heterogeneity among the studies (p= 0.003, I2= 63%). Subgroup analysis demonstrated that heterogeneity was because of the open label trials (p= 0.009, I2= 79%). 

**CONCLUSION: **
Atomoxetine and methylphenidate showed comparable efficacy in the treatment of children and adolescents with ADHD. However, Osmotic (Controlled) Release Oral (Delivery) System (OROS) methylphenidate is more effective than atomoxetine in treatment of ADHD in children and adolescents that is suggested as a first-line treatment in ADHD. Moreover, comparing the immediate release (IR) methylphenidate to atomoxetine did not lead to the benefit of IR methylphenidate.
AD  - Rezaei, Golandam. MSc, Health Technology Assessment of Shahid Sadoughi University of Medical Sciences, Yazd, Iran. g.rezaei.hta@gmail.com. Hosseini, Seyed Alireza. Associate Professor, Food &amp; Drug Research Center, Clinical Trials group, Food and Drug Administration, Tehran, Iran. a.hosseini@fda.gov.ir. Akbari Sari, Ali. PhD, Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. akbarisari@sina.tums.ac.ir. Olyaeemanesh, Alireza. Assistant Professor, National Institute for Health Research, Tehran University of Medical Sciences, Tehran, Iran. arolyaee@gmail.com. Lotfi, Mohamad Hassan. PhD, Biostatistics &amp; Epidemiology Department, Public Health Faculty, Shaheed Sadoughi University of Medical Sciences, Yazd, Iran. mhlotfi56359@gmail.com. Yassini, Mojtaba. Professor of Psychiatry Department of Psychiatry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. yassiniard@yahoo.com. Bidaki, Reza. Associate professor, Department of Psychiatry, Rafsanjan University of Medical Sciences, Rafsanjan, Iran. Reza_Bidaki@yahoo.com. Nouri, Bijan. Assistant Professor, Social Determinants of Health Research Center, Kurdistan University of Medical Sciences Sanandaj, Iran. bijannuri@gmail.com.
AN  - 27390695
AU  - Rezaei,
AU  - G.
AU  - Hosseini,
AU  - S.
AU  - A.
AU  - Akbari
AU  - Sari,
AU  - A.
AU  - Olyaeemanesh,
AU  - A.
AU  - Lotfi,
AU  - M.
AU  - H.
AU  - Yassini,
AU  - M.
AU  - Bidaki,
AU  - R.
AU  - Nouri,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - HAR IKKE DOI
DP  - Ovid Technologies
J2  - Med J Islam Repub Iran
L1  - internal-pdf://1247258562/Rezaei-2016-Comparative efficacy of methylphen.pdf
LA  - English
N1  - Rezaei, Golandam Hosseini, Seyed Alireza Akbari Sari, Ali Olyaeemanesh, Alireza Lotfi, Mohamad Hassan Yassini, Mojtaba Bidaki, Reza Nouri, Bijan
PY  - 2016
SP  - 325
T2  - Medical Journal of the Islamic Republic of Iran
TI  - Comparative efficacy of methylphenidate and atomoxetine in the treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27390695http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27390695&amp;id=doi:&amp;issn=1016-1430&amp;isbn=&amp;volume=30&amp;issue=&amp;spage=325&amp;pages=325&amp;date=2016&amp;title=Medical+Journal+of+the+Islamic+Republic+of+Iran&amp;atitle=Comparative+efficacy+of+methylphenidate+and+atomoxetine+in+the+treatment+of+attention+deficit+hyperactivity+disorder+in+children+and+adolescents%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Rezaei&amp;pid=%3Cauthor%3ERezaei+G%3C%2Fauthor%3E%3CAN%3E27390695%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898838/pdf/mjiri-30-325.pdf
VL  - 30
ER  -
TY  - JOUR
AB  - It has been conclusively established that folic acid supplementation prior to and during early pregnancy (up to 12 weeks of gestation) can prevent neural tube defects (NTDs). 

We hypothesized that folate effects may extend from neuro-structural defects to alterations in neuro-behavioural and emotional skills including autism spectrum disorders (ASDs) and other developmental disorders. 

The objective of this review was to comprehensively evaluate evidence on the impact of folic acid on neurodevelopment other than NTDs. 

We conducted an online search of relevant literature compiled by the National Library of Medicine from Medline and EMBASE (searched on Dec 31, 2014:
AD  - (Gao, Sheng) Department of Obstetrics and Gynecology, Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, China (Gao, Xie, Walker, Wen) OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Faculty of Medicine, Ottawa, Canada (Gao, Walker, Wen) Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada (Xie) Hunan University of Medicine, Department of Nursing, Huaihua, Hunan, China (Xie) McLaughlin Center for Population Risk Assessment, University of Ottawa, Faculty of Medicine, Ottawa, Canada (Sun) Department of Obstetrics and Gynecology, Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China (Asztalos) Centre for Mother, Infant and Child Research, Sunnybrook Health Sciences Centre, Toronto, ON, Canada (Asztalos) Department of Pediatrics and Obstetrics and Gynecology, Faculty of Medicine, University of Toronto, Toronto, Canada (Moddemann) Department of Pediatrics, Child Health and Neonatal Follow-up Program, University of Manitoba, Winnipeg, Canada (Zwaigenbaum) Department of Pediatrics and of Psychiatry, University of Alberta, Edmonton, Canada (Zwaigenbaum) Autism Research Centre, Glenrose Rehabilitation Hospital, Edmonton, Canada (Walker, Wen) School of Epidemiology, Public Health, and Preventive Medicine, University of Ottawa, Ottawa, Canada
AN  - 613337602
AU  - Gao,
AU  - Y.
AU  - Sheng,
AU  - C.
AU  - Xie,
AU  - R.
AU  - H.
AU  - Sun,
AU  - W.
AU  - Asztalos,
AU  - E.
AU  - Moddemann,
AU  - D.
AU  - Zwaigenbaum,
AU  - L.
AU  - Walker,
AU  - M.
AU  - Wen,
AU  - S.
AU  - W.
DA  - November
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1371/journal.pone.0165626
DP  - Ovid Technologies
KW  - article
KW  - attention
KW  - autism
KW  - case control study
KW  - cognition
KW  - cohort analysis
KW  - developmental delay
KW  - developmental disorder
KW  - emotional disorder
KW  - gestational age
KW  - human
KW  - mass screening
KW  - mental disease
KW  - neural tube defect
KW  - pregnancy
KW  - prenatal period
KW  - problem behavior
KW  - progeny
KW  - randomized controlled trial (topic)
KW  - risk factor
KW  - systematic review
KW  - vitamin supplementation
KW  - folic acid
KW  - Bayley Scales of Infant Development
KW  - child
KW  - controlled study
KW  - Embase
KW  - female
KW  - intelligence
KW  - language
KW  - locomotion
KW  - medicine
KW  - Medline
KW  - nervous system development
KW  - screening
KW  - skill
KW  - structure activity relation
L1  - internal-pdf://3144870290/Gao-2016-New perspective on impact of folic ac.pdf
LA  - English
PY  - 2016
T2  - PLoS ONE
TI  - New perspective on impact of folic acid supplementation during pregnancy on neurodevelopment/autism in the offspring children - A systematic review
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0165626&amp;type=printablehttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=613337602http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1371%2Fjournal.pone.0165626&amp;issn=1932-6203&amp;isbn=&amp;volume=11&amp;issue=11&amp;spage=no+pagination&amp;pages=no+pagination&amp;date=2016&amp;title=PLoS+ONE&amp;atitle=New+perspective+on+impact+of+folic+acid+supplementation+during+pregnancy+on+neurodevelopment%2Fautism+in+the+offspring+children+-+A+systematic+review&amp;aulast=Gao&amp;pid=%3Cauthor%3EGao+Y.%3C%2Fauthor%3E%3CAN%3E613337602%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3E
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0165626&amp;type=printable
VL  - 11 (11) (no pagination)
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Peer mediated intervention (PMI) is a promising practice used to increase social skills in children with autism spectrum disorder (ASD). PMIs engage typically developing peers as social models to improve social initiations, responses, and interactions. 

**METHOD: **
The current study is a systematic review examining PMIs for children and adolescents with ASD conducted using group designs. Five studies met the pre-specified review inclusion criteria: four randomized controlled trials and one pre- and post-test design. 

**RESULTS: **
Four of the studies were conducted in school settings, whereas one study was conducted in a camp setting. The studies all reported that participants improved in social skills (e.g., social initiations, social responses, social communication) post intervention. Additionally, sustainment, generalization, and fidelity of implementation were examined. 

**CONCLUSION: **
PMI is a promising approach to address social skills in children with ASD, and this approach can be conducted in meaningful real-word contexts, such as schools. Limitations of the studies as well as future directions are discussed.
AD  - Chang, Ya-Chih. California State University, Los Angeles, USA. Locke, Jill. University of Washington, Seattle, USA.
AN  - 27807466
AU  - Chang,
AU  - Y.
AU  - C.
AU  - Locke,
AU  - J.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.rasd.2016.03.010.
DP  - Ovid Technologies
J2  - Res Autism Spectr Disord
L1  - internal-pdf://3795430412/Chang-2016-A systematic review of peer-mediate.pdf
LA  - English
N1  - Chang, Ya-Chih Locke, Jill
PY  - 2016
SP  - 1-10
T2  - Research in Autism Spectrum Disorders
TI  - A systematic review of peer-mediated interventions for children with autism spectrum disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27807466http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27807466&amp;id=doi:10.1016%2Fj.rasd.2016.03.010&amp;issn=1750-9467&amp;isbn=&amp;volume=27&amp;issue=&amp;spage=1&amp;pages=1-10&amp;date=2016&amp;title=Research+in+Autism+Spectrum+Disorders&amp;atitle=A+systematic+review+of+peer-mediated+interventions+for+children+with+autism+spectrum+disorder.&amp;aulast=Chang&amp;pid=%3Cauthor%3EChang+YC%3C%2Fauthor%3E%3CAN%3E27807466%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087797/pdf/nihms795569.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - Youth suicide is a significant public health problem. 

A systematic review was conducted to examine the effectiveness of school, community and healthcare-based interventions in reducing and preventing suicidal ideation, suicide attempts and deliberate self-harm in young people aged 12-25 years. PsycInfo, PubMed and Cochrane databases were searched to the end of December 2014 to identify randomised controlled trials evaluating the effectiveness of psychosocial interventions for youth suicide. In total, 13,747 abstracts were identified and screened for inclusion in a larger database. 

Of these, 29 papers describing 28 trials fulfilled the inclusion criteria for the current review. The results of the review indicated that just over half of the programs identified had a significant effect on suicidal ideation (Cohen&#039;s d = 0.16-3.01), suicide attempts (phi = 0.04-0.38) or deliberate self-harm (phi = 0.29-0.33; d = 0.42). 

The current review provides preliminary support for the implementation of universal and targeted interventions in all settings, using a diverse range of psychosocial approaches. 

Further quality research is needed to strengthen the evidence-base for suicide prevention programs in this population. In particular, the development of universal school-based interventions is promising given the potential reach of such an approach.
AD  - [Calear, Alison L.; van Spijker, Bregje] Australian Natl Univ, Natl Inst Mental Hlth Res, 63 Eggleston Rd, Acton, ACT 2601, Australia. [Christensen, Helen] Univ New S Wales, Black Dog Inst, Hosp Rd, Randwick, NSW 2031, Australia. [Freeman, Alexander; Fenton, Katherine] Australian Natl Univ, Sch Med, 54 Mills Rd, Acton, ACT 2601, Australia. [Grant, Janie Busby] Univ Canberra, Univ Dr, Bruce, ACT 2617, Australia. [Donker, Tara] Vrije Univ Amsterdam, Dept Clin Psychol, Boechorststr 1, NL-1081 BT Amsterdam, Netherlands. [Donker, Tara] Vrije Univ Amsterdam, EMGO Inst Hlth &amp; Care Res, Boechorststr 7, NL-1081 BT Amsterdam, Netherlands. [Donker, Tara] Vrije Univ Amsterdam, Med Ctr, Boechorststr 7, NL-1081 BT Amsterdam, Netherlands. Calear, AL (reprint author), Australian Natl Univ, Natl Inst Mental Hlth Res, 63 Eggleston Rd, Acton, ACT 2601, Australia. alison.calear@anu.edu.au
AN  - WOS:000377191700002
AU  - Calear,
AU  - A.
AU  - L.
AU  - Christensen,
AU  - H.
AU  - Freeman,
AU  - A.
AU  - Fenton,
AU  - K.
AU  - Grant,
AU  - J.
AU  - B.
AU  - van
AU  - Spijker,
AU  - B.
AU  - Donker,
AU  - T.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-015-0783-4
J2  - Eur. Child Adolesc. Psych.
KW  - Suicide
KW  - Prevention
KW  - Early intervention
KW  - School
KW  - Community
KW  - Healthcare
KW  - randomized controlled-trial
KW  - nominated support team
KW  - deliberate
KW  - self-harm
KW  - group-therapy
KW  - young-adults
KW  - family intervention
KW  - behavior-therapy
KW  - follow-up
KW  - adolescents
KW  - ideation
KW  - Psychology
KW  - Pediatrics
KW  - Psychiatry
L1  - internal-pdf://2985469223/Calear-2016-A systematic review of psychosocia.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DN6NK Times Cited: 2 Cited Reference Count: 53 Calear, Alison L. Christensen, Helen Freeman, Alexander Fenton, Katherine Grant, Janie Busby van Spijker, Bregje Donker, Tara Busby Grant, Janie/D-3778-2009; Busby Grant, Janie/0000-0001-7330-0213; Christensen, Helen/0000-0003-0435-2065 National Health and Medical Research Council (NHMRC) [1013199, 1056964] ALC and HC are supported by National Health and Medical Research Council (NHMRC) Fellowships 1013199 and 1056964. The database used in the current review is maintained by the NHMRC Centre of Research Excellence in Suicide Prevention (1042580). We would like to thank Jacqueline Brewer, John Gosling, Katherine Petrie, Daniela Solomon, Kanupriya Kahlia Hehir and Angeline Tjhin for their assistance in completing the review. 2 14 23 Springer New york 1435-165x
PY  - 2016
SP  - 467-482
T2  - European Child &amp; Adolescent Psychiatry
TI  - A systematic review of psychosocial suicide prevention interventions for youth
UR  - &lt;Go to ISI&gt;://WOS:000377191700002
UR  - https://link.springer.com/article/10.1007/s00787-015-0783-4
UR  - http://download.springer.com/static/pdf/714/art%253A10.1007%252Fs00787-015-0783-4.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-015-0783-4&amp;token2=exp=1489074495~acl=%2Fstatic%2Fpdf%2F714%2Fart%25253A10.1007%25252Fs00787-015-0783-4.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-015-0783-4*~hmac=dc35ba4280335868f5a98b79863f9148349b9b0a57969fafd74c90491dd62528
VL  - 25
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Major depressive disorder is one of the most common mental disorders in children and adolescents. However, whether to use pharmacological interventions in this population and which drug should be preferred are still matters of controversy. Consequently, we aimed to compare and rank antidepressants and placebo for major depressive disorder in young people. 

**METHODS: **
We did a network meta-analysis to identify both direct and indirect evidence from relevant trials. We searched PubMed, the Cochrane Library, Web of Science, Embase, CINAHL, PsycINFO, LiLACS, regulatory agencies&#039; websites, and international registers for published and unpublished, double-blind randomised controlled trials up to May 31, 2015, for the acute treatment of major depressive disorder in children and adolescents. We included trials of amitriptyline, citalopram, clomipramine, desipramine, duloxetine, escitalopram, fluoxetine, imipramine, mirtazapine, nefazodone, nortriptyline, paroxetine, sertraline, and venlafaxine. Trials recruiting participants with treatment-resistant depression, treatment duration of less than 4 weeks, or an overall sample size of less than ten patients were excluded. We extracted the relevant information from the published reports with a predefined data extraction sheet, and assessed the risk of bias with the Cochrane risk of bias tool. The primary outcomes were efficacy (change in depressive symptoms) and tolerability (discontinuations due to adverse events). We did pair-wise meta-analyses using the random-effects model and then did a random-effects network meta-analysis within a Bayesian framework. We assessed the quality of evidence contributing to each network estimate using the GRADE framework. 

This study is registered with PROSPERO, number CRD42015016023. 

**FINDINGS: **
We deemed 34 trials eligible, including 5260 participants and 14 antidepressant treatments. The quality of evidence was rated as very low in most comparisons. For efficacy, only fluoxetine was statistically significantly more effective than placebo (standardised mean difference -0.51, 95% credible interval [CrI] -0.99 to -0.03). In terms of tolerability, fluoxetine was also better than duloxetine (odds ratio [OR] 0.31, 95% CrI 0.13 to 0.95) and imipramine (0.23, 0.04 to 0.78). Patients given imipramine, venlafaxine, and duloxetine had more discontinuations due to adverse events than did those given placebo (5.49, 1.96 to 20.86; 3.19, 1.01 to 18.70; and 2.80, 1.20 to 9.42, respectively). In terms of heterogeneity, the global I(2) values were 33.21% for efficacy and 0% for tolerability. 

**INTERPRETATION: **
When considering the risk-benefit profile of antidepressants in the acute treatment of major depressive disorder, these drugs do not seem to offer a clear advantage for children and adolescents. Fluoxetine is probably the best option to consider when a pharmacological treatment is indicated. 

**FUNDING: **
National Basic Research Program of China (973 Program).

Copyright &copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Cipriani, Andrea. Department of Psychiatry, University of Oxford, Oxford, UK. Electronic address: andrea.cipriani@psych.ox.ac.uk. Zhou, Xinyu. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Del Giovane, Cinzia. Department of Diagnostic, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Modena, Italy. Hetrick, Sarah E. Orygen, The National Centre of Excellence in Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia. Qin, Bin. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Whittington, Craig. Doctor Evidence, Santa Monica, CA, USA. Coghill, David. Division of Neuroscience, School of Medicine, University of Dundee, Dundee, UK; Department of Paediatrics, and Department of Psychiatry, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia. Zhang, Yuqing. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Hazell, Philip. Discipline of Psychiatry, Sydney Medical School, Concord West, NSW, Australia. Leucht, Stefan. Department of Psychiatry and Psychotherapy, Technische Universitat Munchen, Munich, Germany. Cuijpers, Pim. Department of Clinical, Neuro- and Developmental Psychology, VU University Amsterdam, Amsterdam, Netherlands. Pu, Juncai. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Cohen, David. Department of Child and Adolescent Psychiatry, Hopital Pitie-Salpetriere, Institut des Systemes Intelligents et Robotiques, Universite Pierre et Marie Curie, Paris, France. Ravindran, Arun V. Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada. Liu, Yiyun. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Michael, Kurt D. Department of Psychology, Appalachian State University, Boone, NC, USA. Yang, Lining. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Liu, Lanxiang. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China. Xie, Peng. Department of Neurology and Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia. Electronic address: xiepeng973@126.com.
AN  - 27289172
AU  - Cipriani,
AU  - A.
AU  - Zhou,
AU  - X.
AU  - Del
AU  - Giovane,
AU  - C.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Qin,
AU  - B.
AU  - Whittington,
AU  - C.
AU  - Coghill,
AU  - D.
AU  - Zhang,
AU  - Y.
AU  - Hazell,
AU  - P.
AU  - Leucht,
AU  - S.
AU  - Cuijpers,
AU  - P.
AU  - Pu,
AU  - J.
AU  - Cohen,
AU  - D.
AU  - Ravindran,
AU  - A.
AU  - V.
AU  - Liu,
AU  - Y.
AU  - Michael,
AU  - K.
AU  - D.
AU  - Yang,
AU  - L.
AU  - Liu,
AU  - L.
AU  - Xie,
AU  - P.
DA  - Aug 27
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/S0140-6736(16)30385-3
DP  - Ovid Technologies
J2  - Lancet
KW  - Adolescent
KW  - Amitriptyline/ad [Administration &amp; Dosage]
KW  - Amitriptyline/ae [Adverse Effects]
KW  - *Antidepressive Agents/ad [Administration &amp; Dosage]
KW  - *Antidepressive Agents/ae [Adverse Effects]
KW  - Bayes Theorem
KW  - Child
KW  - Citalopram/ad [Administration &amp; Dosage]
KW  - Citalopram/ae [Adverse Effects]
KW  - Clomipramine/ad [Administration &amp; Dosage]
KW  - Clomipramine/ae [Adverse Effects]
KW  - Confounding Factors (Epidemiology)
KW  - *Depressive Disorder, Major/dt [Drug Therapy]
KW  - Desipramine/ad [Administration &amp; Dosage]
KW  - Desipramine/ae [Adverse Effects]
KW  - Double-Blind Method
KW  - Drug Administration Schedule
KW  - Duloxetine Hydrochloride/ad [Administration &amp; Dosage]
KW  - Duloxetine Hydrochloride/ae [Adverse Effects]
KW  - Evidence-Based Medicine
KW  - Fluoxetine/ad [Administration &amp; Dosage]
KW  - Fluoxetine/ae [Adverse Effects]
KW  - Humans
KW  - Imipramine/ad [Administration &amp; Dosage]
KW  - Imipramine/ae [Adverse Effects]
KW  - Mianserin/ad [Administration &amp; Dosage]
KW  - Mianserin/ae [Adverse Effects]
KW  - Mianserin/aa [Analogs &amp; Derivatives]
KW  - Nortriptyline/ad [Administration &amp; Dosage]
KW  - Nortriptyline/ae [Adverse Effects]
KW  - Paroxetine/ad [Administration &amp; Dosage]
KW  - Paroxetine/ae [Adverse Effects]
KW  - Randomized Controlled Trials as Topic
KW  - Research Design
KW  - Sertraline/ad [Administration &amp; Dosage]
KW  - Sertraline/ae [Adverse Effects]
KW  - Treatment Outcome
KW  - Triazoles/ad [Administration &amp; Dosage]
KW  - Triazoles/ae [Adverse Effects]
KW  - Venlafaxine Hydrochloride/ad [Administration &amp; Dosage]
KW  - Venlafaxine Hydrochloride/ae [Adverse Effects]
KW  - 0 (Antidepressive Agents)
KW  - 0 (Triazoles)
KW  - 01K63SUP8D (Fluoxetine)
KW  - 0DHU5B8D6V (Citalopram)
KW  - 1806D8D52K (Amitriptyline)
KW  - 250PJI13LM (Mianserin)
KW  - 41VRH5220H (Paroxetine)
KW  - 59H4FCV1TF (nefazodone)
KW  - 7D7RX5A8MO (Venlafaxine Hydrochloride)
KW  - 9044SC542W (Duloxetine Hydrochloride)
KW  - A051Q2099Q (mirtazapine)
KW  - BL03SY4LXB (Nortriptyline)
KW  - NUV44L116D (Clomipramine)
KW  - OGG85SX4E4 (Imipramine)
KW  - QUC7NX6WMB (Sertraline)
KW  - TG537D343B (Desipramine)
L1  - internal-pdf://1883942838/Cipriani-2016-Comparative efficacy and tolerab.pdf
LA  - English
M3  - Comparative Study Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Cipriani, Andrea Zhou, Xinyu Del Giovane, Cinzia Hetrick, Sarah E Qin, Bin Whittington, Craig Coghill, David Zhang, Yuqing Hazell, Philip Leucht, Stefan Cuijpers, Pim Pu, Juncai Cohen, David Ravindran, Arun V Liu, Yiyun Michael, Kurt D Yang, Lining Liu, Lanxiang Xie, Peng Comment in: Lancet. 2016 Aug 27;388(10047):844-5; PMID: 27289173 S0140-6736(16)30385-3
PY  - 2016
SP  - 881-90
T2  - Lancet
TI  - Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=27289172http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27289172&amp;id=doi:10.1016%2FS0140-6736%2816%2930385-3&amp;issn=0140-6736&amp;isbn=&amp;volume=388&amp;issue=10047&amp;spage=881&amp;pages=881-90&amp;date=2016&amp;title=Lancet&amp;atitle=Comparative+efficacy+and+tolerability+of+antidepressants+for+major+depressive+disorder+in+children+and+adolescents%3A+a+network+meta-analysis.&amp;aulast=Cipriani&amp;pid=%3Cauthor%3ECipriani+A%3C%2Fauthor%3E%3CAN%3E27289172%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0140673616303853/1-s2.0-S0140673616303853-main.pdf?_tid=6d19b2e0-04a3-11e7-9bd8-00000aab0f26&amp;acdnat=1489048741_b5ff7226fef62745a108f86ea8f2c218
UR  - http://ac.els-cdn.com/S0140673616303853/1-s2.0-S0140673616303853-main.pdf?_tid=64ad48e4-04c4-11e7-a982-00000aacb35d&amp;acdnat=1489062900_8a8495cc38ccc2d035fca78ff215477a
VL  - 388
ER  -
TY  - JOUR
AB  - **Background**
Tourette syndrome (TS) and chronic tic disorder (CTD) affect 1-2% of children and young people, but the most effective treatment is unclear. To establish the current evidence base, we conducted a systematic review of interventions for children and young people. 

**Methods**
Databases were searched from inception to 1 October 2014 for placebo-controlled trials of pharmacological, behavioural, physical or alternative interventions for tics in children and young people with TS or CTD. Certainty in the evidence was assessed with the GRADE approach. 

**Results**
Forty trials were included [pharmacological (32), behavioural (5), physical (2), dietary (1)]. For tics/global score there was evidence favouring the intervention from four trials of 2-adrenergic receptor agonists [clonidine and guanfacine, standardised mean difference (SMD)=-0.71; 95% CI -1.03, -0.40; N=164] and two trials of habit reversal training (HRT)/comprehensive behavioural intervention (CBIT) (SMD=-0.64; 95% CI -0.99, -0.29; N=133). Certainty in the effect estimates was moderate. A post hoc analysis combining oral clonidine/guanfacine trials with a clonidine patch trial continued to demonstrate benefit (SMD=-0.54; 95% CI -0.92, -0.16), but statistical heterogeneity was high. Evidence from four trials suggested that antipsychotic drugs improved tic scores (SMD=-0.74; 95% CI -1.08, -0.40; N=76), but certainty in the effect estimate was low. The evidence for other interventions was categorised as low or very low quality, or showed no conclusive benefit. 

**Conclusions**
When medication is considered appropriate for the treatment of tics, the balance of clinical benefits to harm favours 2-adrenergic receptor agonists (clonidine and guanfacine) as first-line agents. Antipsychotics are likely to be useful but carry the risk of harm and so should be reserved for when 2-adrenergic receptor agonists are either ineffective or poorly tolerated. There is evidence that HRT/CBIT is effective, but there is no evidence for HRT/CBIT alone relative to combining medication and HRT/CBIT. There is currently no evidence to suggest that the physical and dietary interventions reviewed are sufficiently effective and safe to be considered as treatments.
AD  - [Whittington, Craig] UCL, Natl Collaborating Ctr Mental Hlth, London, England. [Pennant, Mary; Kendall, Tim] Royal Coll Psychiatrists, Natl Collaborating Ctr Mental Hlth, London, England. [Glazebrook, Cristine; Groom, Madeleine; Jackson, Georgina; Hollis, Chris] Univ Nottingham, Sch Med, Div Psychiat &amp; Appl Psychol, Nottingham, England. [Trayner, Penny] Univ Manchester, Sch Psychol Sci, Manchester, Lancs, England. [Hedderly, Tammy] Guys &amp; St Thomas Hosp, Evelina London Childrens Hosp, Paediat Neurosci, London, England. [Heyman, Isobel; Murphy, Tara] Great Ormond St Hosp Sick Children, Dept Child &amp; Adolescent Mental Hlth, London, England. [Jackson, Stephen] Univ Nottingham, Sch Psychol, Nottingham, England. [Rickards, Hugh] Univ Birmingham, Natl Ctr Mental Hlth, Birmingham, W Midlands, England. [Robertson, Mary; Stern, Jeremy] St George Hosp, Dept Neurol, London, England. Hollis, C (reprint author), Univ Nottingham, Queens Med Ctr, Div Psychiat &amp; Appl Psychol, Dev Psychiat, Nottingham NG7 2UH, England. chris.hollis@nottingham.ac.uk
AN  - WOS:000383399300002
AU  - Whittington,
AU  - C.
AU  - Pennant,
AU  - M.
AU  - Kendall,
AU  - T.
AU  - Glazebrook,
AU  - C.
AU  - Trayner,
AU  - P.
AU  - Groom,
AU  - M.
AU  - Hedderly,
AU  - T.
AU  - Heyman,
AU  - I.
AU  - Jackso,
AU  - G.
AU  - Jackson,
AU  - S.
AU  - Murphy,
AU  - T.
AU  - Rickards,
AU  - H.
AU  - Robertson,
AU  - M.
AU  - Stern,
AU  - J.
AU  - Hollis,
AU  - C.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jcpp.12556
J2  - J. Child Psychol. Psychiatry
KW  - Paediatrics
KW  - Tourette syndrome
KW  - therapy
KW  - tics
KW  - deficit hyperactivity disorder
KW  - european clinical guidelines
KW  - randomized
KW  - controlled-trial
KW  - placebo-controlled trial
KW  - deep brain-stimulation
KW  - quality-of-life
KW  - double-blind
KW  - tic disorders
KW  - behavior-therapy
KW  - pharmacological-treatment
KW  - Psychology
KW  - Psychiatry
L1  - internal-pdf://1220013586/Whittington-2016-Practitioner Review_ Treatmen.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DW1JK Times Cited: 1 Cited Reference Count: 84 Whittington, Craig Pennant, Mary Kendall, Tim Glazebrook, Cristine Trayner, Penny Groom, Madeleine Hedderly, Tammy Heyman, Isobel Jackson, Georgina Jackson, Stephen Murphy, Tara Rickards, Hugh Robertson, Mary Stern, Jeremy Hollis, Chris Hollis, Chris/0000-0003-1083-6744; Whittington, Craig/0000-0002-1950-0334
PY  - 2016
SP  - 988-1004
T2  - Journal of Child Psychology and Psychiatry
TI  - Practitioner Review: Treatments for Tourette syndrome in children and young people - a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000383399300002
UR  - http://onlinelibrary.wiley.com/store/10.1111/jcpp.12556/asset/jcpp12556.pdf?v=1&amp;t=j02h0aba&amp;s=15374906eadb76e3f21a85d99262c063a6b336f2
VL  - 57
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Gross motor skills are fundamental to childhood development. The effectiveness of current physical therapy options for children with mild to moderate gross motor disorders is unknown. The aim of this study was to systematically review the literature to investigate the effectiveness of conservative interventions to improve gross motor performance in children with a range of neurodevelopmental disorders. 

**METHODS: **
A systematic review with meta-analysis was conducted. MEDLINE, EMBASE, AMED, CINAHL, PsycINFO, PEDro, Cochrane Collaboration, Google Scholar databases and clinical trial registries were searched. Published randomised controlled trials including children 3 to &lt;18 years with (i) Developmental Coordination Disorder (DCD) or Cerebral Palsy (CP) (Gross Motor Function Classification System Level 1) or Developmental Delay or Minimal Acquired Brain Injury or Prematurity (&lt;30 weeks gestational age) or Fetal Alcohol Spectrum Disorders; and (ii) receiving non-pharmacological or non-surgical interventions from a health professional and (iii) gross motor outcomes obtained using a standardised assessment tool. Meta-analysis was performed to determine the pooled effect of intervention on gross motor function. Methodological quality and strength of meta-analysis recommendations were evaluated using PEDro and the GRADE approach respectively. 

**RESULTS: **
Of 2513 papers, 9 met inclusion criteria including children with CP (n=2) or DCD (n=7) receiving 11 different interventions. Only two of 9 trials showed an effect for treatment. Using the least conservative trial outcomes a large beneficial effect of intervention was shown (SMD:-0.8; 95% CI:-1.1 to -0.5) with &quot;very low quality&quot; GRADE ratings. Using the most conservative trial outcomes there is no treatment effect (SMD:-0.1; 95% CI:-0.3 to 0.2) with &quot;low quality&quot; GRADE ratings. Study limitations included the small number and poor quality of the available trials. 

**CONCLUSION: **
Although we found that some interventions with a task-orientated framework can improve gross motor outcomes in children with DCD or CP, these findings are limited by the very low quality of the available evidence. High quality intervention trials are urgently needed.
AD  - Lucas, Barbara R. Discipline of Paediatrics and Child Health, The University of Sydney, The Children&#039;s Hospital at Westmead, Clinical School, Locked Bag 4001, Westmead, Sydney, NSW, 2145, Australia. blucas@georgeinstitute.org.au. Lucas, Barbara R. The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, , Missenden Rd, Sydney, NSW, 2050, Australia. blucas@georgeinstitute.org.au. Lucas, Barbara R. Poche Centre for Indigenous Health, Sydney School of Public Health, The University of Sydney, Sydney, NSW, 2006, Australia. blucas@georgeinstitute.org.au. Lucas, Barbara R. Physiotherapy Department, Royal North Shore Hospital, St Leonards, Sydney, NSW, 2065, Australia. blucas@georgeinstitute.org.au. Elliott, Elizabeth J. Discipline of Paediatrics and Child Health, The University of Sydney, The Children&#039;s Hospital at Westmead, Clinical School, Locked Bag 4001, Westmead, Sydney, NSW, 2145, Australia. Elliott, Elizabeth J. The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, , Missenden Rd, Sydney, NSW, 2050, Australia. Elliott, Elizabeth J. The Sydney Children&#039;s Hospital Networks (Westmead), Locked Bag 4001, Westmead, Sydney, NSW, 2145, Australia. Coggan, Sarah. The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, , Missenden Rd, Sydney, NSW, 2050, Australia. Coggan, Sarah. School of Public Health, Curtin University, GPO Box U1987, Perth, WA, 6845, Australia. Pinto, Rafael Z. Pain Management Research Institute, University of Sydney at Royal North Shore Hospital, St Leonards, Sydney, NSW, 2065, Australia. Pinto, Rafael Z. Departamento de Fisioterapia, Faculdade de Ciencias e Tecnologia, UNESP-Univ Estadual Paulista, Presidente Prudente, SP, 19060-900, Brazil. Jirikowic, Tracy. Division of Occupational Therapy, Department of Rehabilitation Medicine, University of Washington, Seattle, WA, 98195, USA. McCoy, Sarah Westcott. Division of Physical Therapy, Department of Rehabilitation Medicine, University of Washington, Seattle, WA, 98195, USA. Latimer, Jane. The George Institute for Global Health, Sydney Medical School, University of Sydney, PO Box M201, , Missenden Rd, Sydney, NSW, 2050, Australia.
AN  - 27899082
AU  - Lucas,
AU  - B.
AU  - R.
AU  - Elliott,
AU  - E.
AU  - J.
AU  - Coggan,
AU  - S.
AU  - Pinto,
AU  - R.
AU  - Z.
AU  - Jirikowic,
AU  - T.
AU  - McCoy,
AU  - S.
AU  - W.
AU  - Latimer,
AU  - J.
DA  - Nov 29
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - DOI 10.1186/s12887-016-0731-6
DP  - Ovid Technologies
J2  - BMC Pediatr
L1  - internal-pdf://3251852699/Lucas-2016-Interventions to improve gross moto.pdf
LA  - English
N1  - Lucas, Barbara R Elliott, Elizabeth J Coggan, Sarah Pinto, Rafael Z Jirikowic, Tracy McCoy, Sarah Westcott Latimer, Jane 10.1186/s12887-016-0731-6
PY  - 2016
SP  - 193
T2  - BMC Pediatrics
TI  - Interventions to improve gross motor performance in children with neurodevelopmental disorders: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27899082http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27899082&amp;id=doi:10.1186%2Fs12887-016-0731-6&amp;issn=1471-2431&amp;isbn=&amp;volume=16&amp;issue=1&amp;spage=193&amp;pages=193&amp;date=2016&amp;title=BMC+Pediatrics&amp;atitle=Interventions+to+improve+gross+motor+performance+in+children+with+neurodevelopmental+disorders%3A+a+meta-analysis.&amp;aulast=Lucas&amp;pid=%3Cauthor%3ELucas+BR%3C%2Fauthor%3E%3CAN%3E27899082%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129231/pdf/12887_2016_Article_731.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - **Background: **
Numerous studies have looked at the efficacy of Parent-Child Interaction Therapy (PCIT) for young children with externalizing behaviour problems.

**Objective: **
The present study compiled these results through a comprehensive review to provide greater clarity regarding the efficacy of this treatment. 

**Methods: **
Using a random effects model, a meta-analysis was conducted to determine the weighted mean effect size. To be included in this analysis, studies were required to have implemented PCIT with children (ages 2-5) with clinically significant externalizing behaviour problems. Twelve studies comprising 254 treated and 118 control group children were included, with the majority of children being White males. This research also assessed whether gender and type of disruptive behaviour disorder (DBD) moderated the effectiveness of PCIT. 

**Results: **
PCIT had a large effect on improving externalizing behaviour problems in children with DBD based on the effect size derived from pre- and post-treatment behavioural outcomes (d = 1.65, 95 % CI [1.41, 1.90], p &lt; .001) and treatment and control group data (d = 1.39, 95 % CI [1.05, 1.73], p &lt; .001). Neither gender nor diagnosis was found to significantly moderate the effectiveness. 

**Conclusions: **
PCIT was found to be an efficacious intervention for child DBD, although the small number of eligible studies and lack of diversity in the sample populations suggests a need for further research. This study has important implications for both practitioners and researchers and provides an efficient summary of the research to date. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Ward, Michelle A.: umward23@myumanitoba.ca; Theule, Jennifer: Jen.Theule@umanitoba.ca; Cheung, Kristene: Kristene.Cheung@umanitoba.ca Theule, Jennifer: Department of Psychology, University of Manitoba, P436 Duff Roblin Building, 190 Dysart Road, Winnipeg, MB, Canada, R3T 2N2, Jen.Theule@umanitoba.ca Ward, Michelle A.: Department of Psychology, University of Manitoba, Winnipeg, MB, Canada Theule, Jennifer: Department of Psychology, University of Manitoba, Winnipeg, MB, Canada Cheung, Kristene: Department of Psychology, University of Manitoba, Winnipeg, MB, Canada
AN  - 2016-09884-001
AU  - Ward,
AU  - M.
AU  - A.
AU  - Theule,
AU  - J.
AU  - Cheung,
AU  - K.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10566-016-9350-5
DP  - Ovid Technologies
KW  - Meta-analysis, Children, Disruptive behaviour disorders, Family therapy
KW  - *Behavior Problems
KW  - *Externalization
KW  - *Family Therapy
KW  - *Parent Child Relations
KW  - Self-Efficacy
KW  - Group &amp; Family Therapy [3313]
KW  - Human Childhood (birth-12 yrs) Adulthood (18 yrs &amp; older)
L1  - internal-pdf://3596740177/Ward-2016-Parent-child interaction therapy for.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 675-690
T2  - Child and Youth Care Forum
TI  - Parent-child interaction therapy for child disruptive behaviour disorders: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-09884-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10566-016-9350-5&amp;issn=1053-1890&amp;isbn=&amp;volume=45&amp;issue=5&amp;spage=675&amp;pages=675-690&amp;date=2016&amp;title=Child+%26+Youth+Care+Forum&amp;atitle=Parent-child+interaction+therapy+for+child+disruptive+behaviour+disorders%3A+A+meta-analysis.&amp;aulast=Ward&amp;pid=%3Cauthor%3EWard%2C+Michelle+A%3C%2Fauthor%3E%3CAN%3E2016-09884-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s10566-016-9350-5
VL  - 45
ER  -
TY  - JOUR
AB  - The objective of this study is to evaluate the effectiveness of parenting programs in reducing child maltreatment and modifying associated factors as well as to examine the moderator variables that are linked to program effects. 

For this meta-analysis, we searched nine electronic databases to identify randomized controlled trials published before September 2013. 

The effect sizes of various outcomes at different time points were computed. From the 3,578 studies identified, we selected 37 studies for further analysis. The total random effect size was 0.296. 

Our results showed that parenting programs successfully reduced substantiated and self-reported child maltreatment reports and reduced the potential for child maltreatment. The programs also reduced risk factors and enhanced protective factors associated with child maltreatment. 

However, the effects of the parenting programs on reducing parental depression and stress were limited. Parenting programs produced positive effects in low-, middle-, and high-income countries and were effective in reducing child maltreatment when applied as primary, secondary, or tertiary child maltreatment intervention. 

In conclusion, parenting programs are effective public health approaches to reduce child maltreatment. The evidence-based service of parenting programs could be widely adopted in future practice. 

Copyright &copy; The Author(s) 2015.
AD  - Chen, Mengtong. Department of Social Work and Social Administration, The University of Hong Kong, Pokfulam, Hong Kong SAR, China chen0823@hku.hk. Chan, Ko Ling. Department of Social Work and Social Administration, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
AN  - 25573846
AU  - Chen,
AU  - M.
AU  - Chan,
AU  - K.
AU  - L.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1524838014566718
DP  - Ovid Technologies
J2  - Trauma Violence Abuse Rev J
KW  - Child
KW  - *Child Abuse/pc [Prevention &amp; Control]
KW  - Humans
KW  - *Parenting
KW  - *Program Evaluation
KW  - Risk Factors
L1  - internal-pdf://1126739113/Chen-2016-Effects of Parenting Programs on Chi.pdf
LA  - English
M3  - Meta-Analysis
N1  - Chen, Mengtong Chan, Ko Ling 1524838014566718
PY  - 2016
SP  - 88-104
T2  - Trauma Violence &amp; Abuse
TI  - Effects of Parenting Programs on Child Maltreatment Prevention: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25573846http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25573846&amp;id=doi:10.1177%2F1524838014566718&amp;issn=1524-8380&amp;isbn=&amp;volume=17&amp;issue=1&amp;spage=88&amp;pages=88-104&amp;date=2016&amp;title=Trauma+Violence+%26+Abuse&amp;atitle=Effects+of+Parenting+Programs+on+Child+Maltreatment+Prevention%3A+A+Meta-Analysis.&amp;aulast=Chen&amp;pid=%3Cauthor%3EChen+M%3C%2Fauthor%3E%3CAN%3E25573846%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 17
ER  -
TY  - JOUR
AB  - **Background**
Obsessive&ndash;compulsive disorder (OCD) is a relatively common and disabling condition.

**Objectives**
To determine the clinical effectiveness, acceptability and cost-effectiveness of pharmacological and psychological interventions for the treatment of OCD in children, adolescents and adults.

**Data sources**
We searched the Cochrane Collaboration Depression, Anxiety and Neurosis Trials Registers, which includes trials from routine searches of all the major databases. Searches were conducted from inception to 31 December 2014.

**Review methods**
We undertook a systematic review and network meta-analysis (NMA) of the clinical effectiveness and acceptability of available treatments. Outcomes for effectiveness included mean differences in the total scores of the Yale&ndash;Brown Obsessive&ndash;Compulsive Scale or its children&rsquo;s version and total dropouts for acceptability. For the cost-effectiveness analysis, we developed a probabilistic model informed by the results of the NMA. All analyses were performed using OpenBUGS version 3.2.3 (members of OpenBUGS Project Management Group; see www.openbugs.net).

**Results**
We included 86 randomised controlled trials (RCTs) in our systematic review. In the NMA we included 71 RCTs (54 in adults and 17 in children and adolescents) for effectiveness and 71 for acceptability (53 in adults and 18 in children and adolescents), comprising 7643 and 7942 randomised patients available for analysis, respectively. In general, the studies were of medium quality. The results of the NMA showed that in adults all selective serotonin reuptake inhibitors (SSRIs) and clomipramine had greater effects than drug placebo. There were no differences between SSRIs, and a trend for clomipramine to be more effective did not reach statistical significance. All active psychological therapies had greater effects than drug placebo. Behavioural therapy (BT) and cognitive therapy (CT) had greater effects than psychological placebo, but cognitive&ndash;behavioural therapy (CBT) did not. BT and CT, but not CBT, had greater effects than medications, but there are considerable uncertainty and methodological limitations that should be taken into account. In children and adolescents, CBT and BT had greater effects than drug placebo, but differences compared with psychological placebo did not reach statistical significance. SSRIs as a class showed a trend for superiority over drug placebo, but the difference did not reach statistical significance. However, the superiority of some individual drugs (fluoxetine, sertraline) was marginally statistically significant. Regarding acceptability, all interventions except clomipramine had good tolerability. In adults, CT and BT had the highest probability of being most cost-effective at conventional National Institute for Health and Care Excellence thresholds. In children and adolescents, CBT or CBT combined with a SSRI were more likely to be cost-effective. The results are uncertain and sensitive to assumptions about treatment effect and the exclusion of trials at high risk of bias.

**Limitations**
The majority of psychological trials included patients who were taking medications. There were few studies in children and adolescents.

**Conclusions**
In adults, psychological interventions, clomipramine, SSRIs or combinations of these are all effective, whereas in children and adolescents, psychological interventions, either as monotherapy or combined with specific SSRIs, were more likely to be effective. Future RCTs should improve their design, in particular for psychotherapy or combined interventions.

**Study registration**
The study is registered as PROSPERO CRD42012002441.

**Funding details**
The National Institute for Health Research Health Technology Assessment programme.
AD  - [Skapinakis, Petros; Lewis, Glyn] UCL, Div Psychiat, London, England. [Caldwell, Deborah; Hollingworth, William; Bryden, Peter; Welton, Nicky; Baxter, Helen; Kessler, David] Univ Bristol, Sch Social &amp; Community Med, Bristol, Avon, England. [Fineberg, Naomi] Univ Hertfordshire, Hatfield, Herts, England. [Fineberg, Naomi] Hertfordshire Partnerships Mental Hlth Trust, Hatfield, Herts, England. [Salkovskis, Paul] Univ Bath, Dept Psychol, Bath, Avon, England. [Churchill, Rachel] Univ York, Ctr Reviews &amp; Disseminat, York, N Yorkshire, England. Skapinakis, P (reprint author), UCL, Div Psychiat, London, England. p.skapinakis@gmail.com
AN  - WOS:000379365000001
AU  - Skapinakis,
AU  - P.
AU  - Caldwell,
AU  - D.
AU  - Hollingworth,
AU  - W.
AU  - Bryden,
AU  - P.
AU  - Fineberg,
AU  - N.
AU  - Salkovskis,
AU  - P.
AU  - Welton,
AU  - N.
AU  - Baxter,
AU  - H.
AU  - Kessler,
AU  - D.
AU  - Churchill,
AU  - R.
AU  - Lewis,
AU  - G.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3310/hta20430
J2  - Health Technol. Assess.
KW  - randomized controlled-trial
KW  - quality-of-life
KW  - cognitive-behavior
KW  - therapy
KW  - placebo-controlled trial
KW  - dsm-iii-r
KW  - serotonin reuptake
KW  - inhibitors
KW  - long-term treatment
KW  - epidemiologic catchment-area
KW  - prospective follow-up
KW  - mental-health survey
KW  - Health Care Sciences &amp; Services
L1  - internal-pdf://0610777852/3003424.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DQ7CR Times Cited: 1 Cited Reference Count: 274 Skapinakis, Petros Caldwell, Deborah Hollingworth, William Bryden, Peter Fineberg, Naomi Salkovskis, Paul Welton, Nicky Baxter, Helen Kessler, David Churchill, Rachel Lewis, Glyn Welton, Nicky/0000-0003-2198-3205 National Institute for Health Research Health Technology Assessment programme The National Institute for Health Research Health Technology Assessment programme. 1 19 23 Nihr journals library Southampton 2046-4924
PY  - 2016
SP  - 1-+
T2  - Health Technology Assessment
TI  - A systematic review of the clinical effectiveness and cost-effectiveness of pharmacological and psychological interventions for the management of obsessive-compulsive disorder in children/adolescents and adults
UR  - &lt;Go to ISI&gt;://WOS:000379365000001
VL  - 20
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Youth violence recidivism remains a significant public health crisis in the United States. Violence prevention is a requirement of all trauma centers, yet little is known about the effectiveness of these programs. Therefore, this systematic review summarizes the effectiveness of trauma center-based youth violence prevention programs. 

**METHODS: **
A systematic review of articles from MEDLINE, CINAHL, and PsychINFO databases was performed to identify eligible control trials or observational studies. Included studies were from 1970 to 2013, describing and evaluating an intervention, were trauma center based, and targeted youth injured by violence (tertiary prevention). The social ecological model provided the guiding framework, and findings are summarized qualitatively. 

**RESULTS: **
Ten studies met eligibility requirements. Case management and brief intervention were the primary strategies, and 90% of the studies showed some improvement in one or more outcome measures. These results held across both social ecological level and setting: both emergency department and inpatient unit settings. 

**CONCLUSIONS: **
Brief intervention and case management are frequent and potentially effective trauma center-based violence prevention interventions. Case management initiated as an inpatient and continued beyond discharge was the most frequently used intervention and was associated with reduced rearrest or reinjury rates. Further research is needed, specifically longitudinal studies using experimental designs with high program fidelity incorporating uniform direct outcome measures. However, this review provides initial evidence that trauma centers can intervene with the highest of risk patients and break the youth violence recidivism cycle. 

Copyright &copy; The Author(s) 2015.
AD  - Mikhail, Judy Nanette. Medical University of South Carolina, Charleston, SC, USA jmikhail@comcast.net. Nemeth, Lynne Sheri. Medical University of South Carolina, Charleston, SC, USA.
AN  - 26123004
AU  - Mikhail,
AU  - J.
AU  - N.
AU  - Nemeth,
AU  - L.
AU  - S.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1524838015584373
DP  - Ovid Technologies
J2  - Trauma Violence Abuse Rev J
L1  - internal-pdf://0667909666/Mikhail-2016-Trauma Center Based Youth Violenc.pdf
LA  - English
N1  - Mikhail, Judy Nanette Nemeth, Lynne Sheri 1524838015584373
PY  - 2016
SP  - 500-519
T2  - Trauma Violence &amp; Abuse
TI  - Trauma Center Based Youth Violence Prevention Programs: An Integrative Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26123004http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26123004&amp;id=doi:10.1177%2F1524838015584373&amp;issn=1524-8380&amp;isbn=&amp;volume=17&amp;issue=5&amp;spage=500&amp;pages=500-519&amp;date=2016&amp;title=Trauma+Violence+%26+Abuse&amp;atitle=Trauma+Center+Based+Youth+Violence+Prevention+Programs%3A+An+Integrative+Review.&amp;aulast=Mikhail&amp;pid=%3Cauthor%3EMikhail+JN%3C%2Fauthor%3E%3CAN%3E26123004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 17
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
An increasing number of studies suggest possible beneficial effects of exercise in alleviating ADHD functional outcomes. The current study provides a quantitative meta-analysis of the available studies investigating this relationship. 

**METHOD: **
Studies reporting on the effects of physical exercise on motor skills and executive functions in children with ADHD were identified through Cochrane, PsycInfo, PubMed, Web of Science databases. Ten publications were selected. Random-effects model was used to calculate effect sizes. 

**RESULTS: **
There was a significant effect of exercise on ADHD functional outcomes (g = 0.627). Longer exercise intervention duration was consistently associated with larger effect sizes. Effect sizes were not related to exercise intensity, mean age of participants, or gender distribution. 

**CONCLUSION: **
Results suggest that exercise has a modest positive impact on ADHD functional outcomes, such as executive functions and motor skills, with longer interventions yielding better results. 

Copyright &copy; The Author(s) 2016.
AD  - Vysniauske, Ruta. Vilnius University Children&#039;s Hospital, Lithuania kaminsku.ruta@gmail.com. Verburgh, Lot. Vrije Universiteit Amsterdam, The Netherlands. Oosterlaan, Jaap. Vrije Universiteit Amsterdam, The Netherlands. Molendijk, Marc L. Leiden University, The Netherlands.
AN  - 26861158
AU  - Vysniauske,
AU  - R.
AU  - Verburgh,
AU  - L.
AU  - Oosterlaan,
AU  - J.
AU  - Molendijk,
AU  - M.
AU  - L.
DA  - Feb 09
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1087054715627489
DP  - Ovid Technologies
J2  - J Atten Disord
L1  - internal-pdf://3826377368/Vysniauske-2016-The Effects of Physical Exerci.pdf
LA  - English
N1  - Vysniauske, Ruta Verburgh, Lot Oosterlaan, Jaap Molendijk, Marc L Using Smart Source Parsing Feb 1087054715627489
PY  - 2016
SP  - 09
T2  - Journal of Attention Disorders
TI  - The Effects of Physical Exercise on Functional Outcomes in the Treatment of ADHD: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=26861158http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26861158&amp;id=doi:10.1177%2F1087054715627489&amp;issn=1087-0547&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2016&amp;title=Journal+of+Attention+Disorders&amp;atitle=The+Effects+of+Physical+Exercise+on+Functional+Outcomes+in+the+Treatment+of+ADHD%3A+A+Meta-Analysis.&amp;aulast=Vysniauske&amp;pid=%3Cauthor%3EVysniauske+R%3C%2Fauthor%3E%3CAN%3E26861158%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 09
ER  -
TY  - JOUR
AB  - Youth residing in out-of-home care settings have often been exposed to childhood trauma, and commonly report experiencing adverse outcomes after transitioning from care. 

This meta-analysis appraised internationally published literature investigating the impact of transitional programme participation (among youth with a baseline age of 15-24 years) on post-transition outcomes of housing, education, employment, mental health and substance use. A comprehensive search of sociology (e.g. ProQuest Sociology), psychology (e.g. PsycInfo) and health (e.g. ProQuest Family Health) electronic abstraction databases was conducted for the period 1990-2014. 

Search terms included &#039;out-of-home care&#039;, &#039;transition&#039;, &#039;housing&#039;, &#039;education&#039;, &#039;employment&#039;, &#039;mental health&#039; and &#039;substance use&#039;. Nineteen studies, all from the United States, met the inclusion criteria and were included in the meta-analysis. Living independently and homelessness were the most commonly described housing outcomes. Rates of post-transition employment varied, while rates of post-secondary education were low. 

Depression and alcohol use were commonly reported among transitioning youth. Findings of the meta-analysis showed that attention should be given to the potential benefit of transitional programme participation on outcomes such as housing, employment and education. 

Moderator analyses showed that these benefits may differ based on study design, sample size and sampling unit, but not for mean age or gender. Detailed and rigorous research is needed internationally to examine the characteristics of transitional programmes resulting in more successful outcomes for youth, and whether these outcomes are sustained longitudinally. 

Copyright &copy; 2016 John Wiley &amp; Sons Ltd.
AD  - Heerde, Jessica A. Learning Sciences Institute Australia, Australian Catholic University, Fitzroy, Victoria, Australia. Hemphill, Sheryl A. Learning Sciences Institute Australia, Australian Catholic University, Fitzroy, Victoria, Australia. Scholes-Balog, Kirsty E. Learning Sciences Institute Australia, Australian Catholic University, Fitzroy, Victoria, Australia.
AN  - 27109440
AU  - Heerde,
AU  - J.
AU  - A.
AU  - Hemphill,
AU  - S.
AU  - A.
AU  - Scholes-Balog,
AU  - K.
AU  - E.
DA  - Apr 24
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/hsc.12348
DP  - Ovid Technologies
J2  - Health Soc Care Community
L1  - internal-pdf://0911080418/Heerde_et_al-2016-Health_&amp;_Social_Care_in_the_.pdf
LA  - English
M3  - Review
N1  - Heerde, Jessica A Hemphill, Sheryl A Scholes-Balog, Kirsty E Using Smart Source Parsing Apr
PY  - 2016
SP  - 24
T2  - Health and Social Care in the Community
TI  - The impact of transitional programmes on post-transition outcomes for youth leaving out-of-home care: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=27109440http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27109440&amp;id=doi:10.1111%2Fhsc.12348&amp;issn=0966-0410&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2016&amp;title=Health+%26+Social+Care+in+the+Community&amp;atitle=The+impact+of+transitional+programmes+on+post-transition+outcomes+for+youth+leaving+out-of-home+care%3A+a+meta-analysis.&amp;aulast=Heerde&amp;pid=%3Cauthor%3EHeerde+JA%3C%2Fauthor%3E%3CAN%3E27109440%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
VL  - 24
ER  -
TY  - JOUR
AB  - **Objective: **
The purpose of this review was to examine the treatment effect of physical exercise on depressive symptoms for adolescents aged 13 to 17 years. 

**Method: **
A systematic search of 7 electronic databases identified relevant randomized controlled trials. Following removal of duplicates, 543 texts were screened for eligibility. Screening, data extraction, and trial methodological quality assessment (using the Delphi list) were undertaken by 2 independent researchers. Standardized mean differences were used for pooling postintervention depressive symptom scores. 

**Results: **
Eleven trials met the inclusion criteria, 8 of which provided the necessary data for calculation of standardized effect size. Exercise showed a statistically significant moderate overall effect on depressive symptom reduction (standardized mean difference [SMD] = -0.48, 95% CI = -0.87, -0.10, p =.01, I-2 = 67%). Among trials with higher methodological scoring, a nonsignificant moderate effect was recorded (SMD = -0.41, 95% CI = -0.86, 0.05, p =.08). In trials with exclusively clinical samples, exercise showed a statistically significant moderate effect on depressive symptoms with lower levels of heterogeneity (SMD = -0.43, 95% CI = -0.84, 0.02, p =.04, I-2 = 44%). 

**Conclusion: **
Physical exercise appears to improve depressive symptoms in adolescents, especially in clinical samples in which the moderate antidepressant effect, higher methodological quality, and lowered statistical heterogeneity suggest that exercise may be a useful treatment strategy for depression. Larger trials with clinical samples that adequately minimize the risk of bias are required for firmer conclusions on the effectiveness of exercise as an antidepressant treatment.
AD  - [Carter, Tim; Meade, Oonagh; Callaghan, Patrick] Univ Nottingham, Nottingham NG7 2RD, England. [Morres, Ioannis D.] Univ Thessaly, Volos, Greece. Carter, T (reprint author), Inst Mental Hlth, Room D25,Triumph Rd, Nottingham NG7 2TU, England. Timothy.carter@nottingham.ac.uk
AN  - WOS:000378985200008
AU  - Carter,
AU  - T.
AU  - Morres,
AU  - I.
AU  - D.
AU  - Meade,
AU  - O.
AU  - Callaghan,
AU  - P.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jaac.2016.04.016
J2  - J. Am. Acad. Child Adolesc. Psychiatr.
KW  - exercise
KW  - randomized controlled trial
KW  - depression
KW  - adolescents
KW  - meta-analysis
KW  - randomized controlled-trial
KW  - physical-activity
KW  - mental-health
KW  - young-people
KW  - school
KW  - children
KW  - fitness
KW  - community
KW  - responses
KW  - Psychology
KW  - Pediatrics
KW  - Psychiatry
L1  - internal-pdf://0987146323/Carter-2016-The Effect of Exercise on Depressi.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DQ1UF Times Cited: 2 Cited Reference Count: 36 Carter, Tim Morres, Ioannis D. Meade, Oonagh Callaghan, Patrick 2 15 18 Elsevier science inc New york 1527-5418
PY  - 2016
SP  - 580-590
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - The Effect of Exercise on Depressive Symptoms in Adolescents: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000378985200008
UR  - http://ac.els-cdn.com/S0890856716301708/1-s2.0-S0890856716301708-main.pdf?_tid=ee4b8a4e-04c3-11e7-a0f2-00000aab0f6b&amp;acdnat=1489062702_20adc912ba48cb2c1adb2df78d8f2167
VL  - 55
ER  -
TY  - JOUR
AB  - Attention deficit hyperactivity disorder (ADHD) is one of the most common neurobehavioral disorders. We carried out this comparison of multiple treatments based on sufficient data in attempt to evaluate the efficacy and safety of ADHD medication for children and adolescents. PubMed, Embase and the Cochrane Database were used to search for relevant articles. 

Changes in the ADHD Rating Scale (ADHD-RS) scores and the Conners&#039; Parent Rating Scale-Revised (CPRS) scores were used as outcomes for efficacy. Withdrawals due to all-cause, adverse effects and lack of efficacy were defined as primary outcomes evaluating the safety of such medications. Both pair-wise and network meta-analyses were performed. 

Efficacy and safety of atomoxetine (ATX), bupropion (BUP), clonidine hydrochloride (CLON), guanfacine extended release (GXR), lisdexamfetamine dimesylate (LDX), and methylphenidate (MPH) were evaluated. LDX has the highest efficacy and a relatively lower rate of adverse effects compared to BUP, CLON and GXR. MPH has the lowest incidence rate of adverse effects and takes second place concerning ADHD-RS scores and third place concerning CPRS scores. 

ATX has the lowest incidence rate of all-cause withdrawals. The efficacy of ATX seems, however, to be lower than CLON, GXR, LDX and MPH. Adversely, BUP has the highest incidence rate of withdrawals and the second highest probability of causing adverse effects as well as lack of efficacy; therefore it should not be recommended as a treatment for ADHD. 

Copyright &copy; 2016 Springer Science+Business Media New York
AD  - (Li, Gao, He, Zhang, Wang) Department of Paediatrics, Huaihe Hospital, Henan University, No. 115 Ximen Street, Kaifeng, Henan 475000, China Y. Li, Department of Paediatrics, Huaihe Hospital, Henan University, No. 115 Ximen Street, Kaifeng, Henan 475000, China. E-mail: leeyeeeng@163.com
AN  - 612732228
AU  - Li,
AU  - Y.
AU  - Gao,
AU  - J.
AU  - He,
AU  - S.
AU  - Zhang,
AU  - Y.
AU  - Wang,
AU  - Q.
DA  - 13 Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s12035-016-0179-6
DP  - Ovid Technologies
KW  - adhd
KW  - Efficacy
KW  - Network meta-analysis
KW  - Safety
KW  - adolescent
KW  - adverse drug reaction
KW  - attention deficit disorder
KW  - child
KW  - Cochrane Library
KW  - comparative effectiveness
KW  - drug combination
KW  - drug withdrawal
KW  - Embase
KW  - human
KW  - incidence
KW  - Medline
KW  - meta analysis
KW  - pharmacokinetics
KW  - probability
KW  - rating scale
KW  - side effect
KW  - systematic review
KW  - amfebutamone
KW  - atomoxetine
KW  - clonidine
KW  - guanfacine
KW  - lisdexamfetamine
KW  - methylphenidate
L1  - internal-pdf://2078555112/Li-2016-An Evaluation on the Efficacy and Safe.pdf
LA  - English
M3  - In Press
PY  - 2016
SP  - 1-15
T2  - Molecular Neurobiology
TI  - An Evaluation on the Efficacy and Safety of Treatments for Attention Deficit Hyperactivity Disorder in Children and Adolescents: a Comparison of Multiple Treatments
UR  - http://www.springer.com/biomed/neuroscience/journal/12035http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=612732228http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1007%2Fs12035-016-0179-6&amp;issn=0893-7648&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-15&amp;date=2016&amp;title=Molecular+Neurobiology&amp;atitle=An+Evaluation+on+the+Efficacy+and+Safety+of+Treatments+for+Attention+Deficit+Hyperactivity+Disorder+in+Children+and+Adolescents%3A+a+Comparison+of+Multiple+Treatments&amp;aulast=Li&amp;pid=%3Cauthor%3ELi+Y.%3C%2Fauthor%3E%3CAN%3E612732228%3C%2FAN%3E%3CDT%3EJournal%3A+Article+In+Press%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Background:** 
Children and adolescents who have experienced trauma are at high risk of developing post-traumatic stress disorder (PTSD) and other negative emotional, behavioural and mental health outcomes, all of which are associated with high personal and health costs. A wide range of psychological treatments are used to prevent negative outcomes associated with trauma in children and adolescents.

**Objectives:** 
To assess the effects of psychological therapies in preventing PTSD and associated negative emotional, behavioural and mental health outcomes in children and adolescents who have undergone a traumatic event.

**Search methods:** 
We searched the Cochrane Common Mental Disorders Group&#039;s Specialised Register to 29 May 2015. This register contains reports of relevant randomised controlled trials from The Cochrane Library (all years), EMBASE (1974 to date), MEDLINE (1950 to date) and PsycINFO (1967 to date). We also checked reference lists of relevant studies and reviews. We did not restrict the searches by date, language or publication status.

**Selection criteria:** 
All randomised controlled trials of psychological therapies compared with a control such as treatment as usual, waiting list or no treatment, pharmacological therapy or other treatments in children or adolescents who had undergone a traumatic event.

**Data collection and analysis:**
Two members of the review group independently extracted data. We calculated odds ratios for binary outcomes and standardised mean differences for continuous outcomes using a random-effects model. We analysed data as short-term (up to and including one month after therapy), medium-term (one month to one year after therapy) and long-term (one year or longer).

**Main results:** 
Investigators included 6201 participants in the 51 included trials. Twenty studies included only children, two included only preschool children and ten only adolescents; all others included both children and adolescents. Participants were exposed to sexual abuse in 12 trials, to war or community violence in ten, to physical trauma and natural disaster in six each and to interpersonal violence in three; participants had suffered a life-threatening illness and had been physically abused or maltreated in one trial each. Participants in remaining trials were exposed to a range of traumas. Most trials compared a psychological therapy with a control such as treatment as usual, wait list or no treatment. Seventeen trials used cognitive-behavioural therapy (CBT); four used family therapy; three required debriefing; two trials each used eye movement desensitisation and reprocessing (EMDR), narrative therapy, psychoeducation and supportive therapy; and one trial each provided exposure and CBT plus narrative therapy. Eight trials compared CBT with supportive therapy, two compared CBT with EMDR and one trial each compared CBT with psychodynamic therapy, exposure plus supportive therapy with supportive therapy alone and narrative therapy plus CBT versus CBT alone. Four trials compared individual delivery of psychological therapy to a group model of the same therapy, and one compared CBT for children versus CBT for both mothers and children.The likelihood of being diagnosed with PTSD in children and adolescents who received a psychological therapy was significantly reduced compared to those who received no treatment, treatment as usual or were on a waiting list for up to a month following treatment (odds ratio (OR) 0.51, 95% confidence interval (CI) 0.34 to 0.77; number needed to treat for an additional beneficial outcome (NNTB) 6.25, 95% CI 3.70 to 16.67; five studies; 874 participants). However the overall quality of evidence for the diagnosis of PTSD was rated as very low. PTSD symptoms were also significantly reduced for a month after therapy (standardised mean difference (SMD) -0.42, 95% CI -0.61 to -0.24; 15 studies; 2051 participants) and the quality of evidence was rated as low. These effects of psychological therapies were not apparent over the longer term.CBT was found to be no more or less effective than EMDR and supportive ther p in reducing diagnosis of PTSD in the short term (OR 0.74, 95% CI 0.29 to 1.91; 2 studies; 160 participants), however this was considered very low quality evidence. For reduction of PTSD symptoms in the short term, there was a small effect favouring CBT over EMDR, play therapy and supportive therapies (SMD -0.24, 95% CI -0.42 to -0.05; 7 studies; 466 participants). The quality of evidence for this outcome was rated as moderate.We did not identify any studies that compared pharmacological therapies with psychological therapies.

**Authors&#039; conclusions:**
The meta-analyses in this review provide some evidence for the effectiveness of psychological therapies in prevention of PTSD and reduction of symptoms in children and adolescents exposed to trauma for up to a month. However, our confidence in these findings is limited by the quality of the included studies and by substantial heterogeneity between studies. Much more evidence is needed to demonstrate the relative effectiveness of different psychological therapies for children exposed to trauma, particularly over the longer term. High-quality studies should be conducted to compare these therapies.
AN  - CD012371
AU  - Gillies,
AU  - D.
AU  - Maiocchi,
AU  - L.
AU  - Bhandari,
AU  - A.
AU  - P.
AU  - Taylor,
AU  - F.
AU  - Gray,
AU  - C.
AU  - O&#039;Brien,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd012371
L1  - internal-pdf://0955230247/Gillies-2016-Psychological therapies for child.pdf
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological therapies for children and adolescents exposed to trauma
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD012371/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD012371/asset/CD012371.pdf?v=1&amp;t=iw7ktp2f&amp;s=e69f97a59f92342c449135fa21e77eef2964e540
ER  -
TY  - JOUR
AB  - **Objective: **
A diagnosis of autism spectrum disorder (ASD) is often accompanied by challenging behaviour that may limit the ability to engage in education, employment, or social settings. The purpose of this review was to examine the effectiveness of self-management interventions in reducing challenging behaviours for individuals diagnosed with ASD. This review included self-management interventions that specifically targeted a reduction in challenging behaviours as well as studies that specifically targeted skill acquisition and described improvements in challenging behaviours as a collateral effect of the intervention.

**Method: **
Studies were located by conducting a systematic search of peer-reviewed literature published in English prior to October 2015. The PsycINFO and ERIC databases were searched. A quality assessment was conducted using the What Works Clearinghouse (WWC) guidelines. A final data set of 12 single-subject research design studies that met quality standards was subsequently analysed. Treatment effect sizes were calculated using the percentage of non-overlapping data. 

**Results: **
Results were analysed by age, gender, symptom severity, presentation of problem behaviour, and the presence of functional behaviour assessments. Results indicated that self-management interventions are effective at decreasing challenging behaviour for children aged four to 18 years who may be described as either high or low functioning. 

**Conclusions: **
Self-management of challenging behaviour was identified as an emerging treatment, and inclusion within a positive behaviour support framework was argued. Important areas for consideration in future research are described. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Carr, Monica E.: mcarr.phd@gmail.com Carr, Monica E.: Melbourne Graduate School of Education, University of Melbourne, 234 Queensberry Street, Melbourne, VIC, Australia, 3010, mcarr.phd@gmail.com Carr, Monica E.: Melbourne Graduate School of Education, University of Melbourne, Melbourne, VIC, Australia
AN  - 2016-36158-008
AU  - Carr,
AU  - M.
AU  - E.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/ap.12227
DP  - Ovid Technologies
KW  - autism, challenging behaviour, PBS, self-management, social skills, treatment effect
KW  - *Autism Spectrum Disorders
KW  - *Behavior Problems
KW  - *Self-Management
KW  - Social Skills
KW  - Developmental Disorders &amp; Autism [3250]
KW  - Behavior Therapy &amp; Behavior Modification [3312]
KW  - Human Childhood (birth-12 yrs) Preschool Age (2-5 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older) Young Adulthood (18-29 yrs)
L1  - internal-pdf://0894871432/Carr-2016-Self-management of challenging behav.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 316-333
T2  - Australian Psychologist
TI  - Self-management of challenging behaviours associated with autism spectrum disorder: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-36158-008http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1111%2Fap.12227&amp;issn=0005-0067&amp;isbn=&amp;volume=51&amp;issue=4&amp;spage=316&amp;pages=316-333&amp;date=2016&amp;title=Australian+Psychologist&amp;atitle=Self-management+of+challenging+behaviours+associated+with+autism+spectrum+disorder%3A+A+meta-analysis.&amp;aulast=Carr&amp;pid=%3Cauthor%3ECarr%2C+Monica+E%3C%2Fauthor%3E%3CAN%3E2016-36158-008%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1111/ap.12227/asset/ap12227.pdf?v=1&amp;t=j02dd8kv&amp;s=0c48e132d8b73cac8921f5296e9739debd832dac
VL  - 51
ER  -
TY  - JOUR
AB  - **Background: **
Tourette syndrome (TS) is a neurodevelopmental condition characterised by chronic motor and vocal tics affecting up to 1% of school-age children and young people and is associated with significant distress and psychosocial impairment. 

**Objective: **
To conduct a systematic review of the benefits and risks of pharmacological, behavioural and physical interventions for tics in children and young people with TS (part 1) and to explore the experience of treatment and services from the perspective of young people with TS and their parents (part 2). 

**Data Sources: **
For the systematic reviews (parts 1 and 2), mainstream bibliographic databases, The Cochrane Library, education, social care and grey literature databases were searched using subject headings and text words for tic(star) and Tourette(star) from database inception to January 2013. 

**Review/research methods: **
For part 1, randomised controlled trials and controlled before-and-after studies of pharmacological, behavioural or physical interventions in children or young people (aged &lt; 18 years) with TS or chronic tic disorder were included. Mixed studies and studies in adults were considered as supporting evidence. Risk of bias associated with each study was evaluated using the Cochrane tool. When there was sufficient data, random-effects meta-analysis was used to synthesize the evidence and the quality of evidence for each outcome was assessed using the Grading of Recommendations Assessment, Development and Evaluation approach. For part 2, qualitative studies and survey literature conducted in populations of children/young people with TS or their carers or in health professionals with experience of treating TS were included in the qualitative review. Results were synthesized narratively. In addition, a national parent/carer survey was conducted via the Tourettes Action website. Participants included parents of children and young people with TS aged under 18 years. Participants (young people with TS aged 10-17 years) for the in-depth interviews were recruited via a national survey and specialist Tourettes clinics in the UK. 

**Results: **
For part 1, 70 studies were included in the quantitative systematic review. The evidence suggested that for treating tics in children and young people with TS, antipsychotic drugs [standardised mean difference (SMD) -0.74, 95% confidence interval (CI) -1.08 to -0.41; n = 75] and noradrenergic agents [clonidine (Dixarit (R), Boehringer Ingelheim) and guanfacine: SMD -0.72, 95% CI -1.03 to -0.40; n = 164] are effective in the short term. There was little difference among antipsychotics in terms of benefits, but adverse effect profiles do differ. Habit reversal training (HRT)/comprehensive behavioural intervention for tics (CBIT) was also shown to be effective (SMD -0.64, 95% CI -0.99 to -0.29; n = 133). For part 2, 295 parents/carers of children and young people with TS contributed useable survey data. Forty young people with TS participated in in-depth interviews. Four studies were in the qualitative review. Key themes were difficulties in accessing specialist care and behavioural interventions, delay in diagnosis, importance of anxiety and emotional symptoms, lack of provision of information to schools and inadequate information regarding medication and adverse effects. 

**Limitations: **
The number and quality of clinical trials is low and this downgrades the strength of the evidence and conclusions. 

**Conclusions: **
Antipsychotics, noradrenergic agents and HRT/CBIT are effective in reducing tics in children and young people with TS. The balance of benefits and harms favours the most commonly used medications: risperidone (Risperdal (R), Janssen), clonidine and aripiprazole (Abilify (R), Otsuka). Larger and better-conducted trials addressing important clinical uncertainties are required. Further research is needed into widening access to behavioural interventions through use of technology including mobile applications (&#039;apps&#039;) and video consultation. 

**Study registration:** 
This study is registered as PROSPERO CRD42012002059.
AD  - [Hollis, Chris; Cuenca, Jose; Glazebrook, Cris; Groom, Madeleine; Jackson, Georgina M.] Univ Nottingham, Div Psychiat &amp; Appl Psychol, Inst Mental Hlth, Innovat Pk, Nottingham NG7 2RD, England. [Pennant, Mary; Kendall, Tim; Whittington, Craig; Stockton, Sarah; Larsson, Linnea] Royal Coll Psychiatrists, Natl Collaborating Ctr Mental Hlth, London SW1X 8PG, England. [Bunton, Penny] Univ Manchester, Sch Psychol Sci, Manchester, Lancs, England. [Dobson, Suzanne; Stern, Jeremy] Tourettes Act, Farnborough, Hants, England. [Hedderly, Tammy] Kings Coll Hosp NHS Fdn Trust, Paediat Neurol Dept, London, England. [Heyman, Isobel] Great Ormond St Hosp Sick Children, Dept Child &amp; Adolescent Mental Hlth, Great Ormond St, London WC1N 3JH, England. [Jackson, Stephen] Univ Nottingham, Sch Psychol, Nottingham NG7 2RD, England. [Murphy, Tara] UCL, Inst Neurol, London, England. [Rickards, Hugh] Natl Ctr Mental Hlth, Birmingham, W Midlands, England. [Robertson, Mary] St Georges Univ Hosp NHS Fdn Trust, Dept Neurol, London, England. Hollis, C (reprint author), Univ Nottingham, Div Psychiat &amp; Appl Psychol, Inst Mental Hlth, Innovat Pk, Nottingham NG7 2RD, England. Chris.Hollis@nottingham.ac.uk
AN  - WOS:000369106600001
AU  - Hollis,
AU  - C.
AU  - Pennant,
AU  - M.
AU  - Cuenca,
AU  - J.
AU  - Glazebrook,
AU  - C.
AU  - Kendall,
AU  - T.
AU  - Whittington,
AU  - C.
AU  - Stockton,
AU  - S.
AU  - Larsson,
AU  - L.
AU  - Bunton,
AU  - P.
AU  - Dobson,
AU  - S.
AU  - Groom,
AU  - M.
AU  - Hedderly,
AU  - T.
AU  - Heyman,
AU  - I.
AU  - Jackson,
AU  - G.
AU  - M.
AU  - Jackson,
AU  - S.
AU  - Murphy,
AU  - T.
AU  - Rickards,
AU  - H.
AU  - Robertson,
AU  - M.
AU  - Stern,
AU  - J.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3310/hta20040
J2  - Health Technol. Assess.
KW  - deep brain-stimulation
KW  - deficit hyperactivity disorder
KW  - obsessive-compulsive disorder
KW  - randomized controlled-trial
KW  - placebo-controlled trial
KW  - attention-deficit/hyperactivity disorder
KW  - transcranial magnetic stimulation
KW  - antistreptococcal antibody-titers
KW  - double-blind
KW  - habit-reversal
KW  - Health Care Sciences &amp; Services
L1  - internal-pdf://2290485505/3003385.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DC3GB Times Cited: 1 Cited Reference Count: 219 Hollis, Chris Pennant, Mary Cuenca, Jose Glazebrook, Cris Kendall, Tim Whittington, Craig Stockton, Sarah Larsson, Linnea Bunton, Penny Dobson, Suzanne Groom, Madeleine Hedderly, Tammy Heyman, Isobel Jackson, Georgina M. Jackson, Stephen Murphy, Tara Rickards, Hugh Robertson, Mary Stern, Jeremy Emchi, Karma/Q-1952-2016; Hollis, Chris/0000-0003-1083-6744; Whittington, Craig/0000-0002-1950-0334 National Institute for Health Research Health Technology Assessment programme The National Institute for Health Research Health Technology Assessment programme. 1 12 21 Nihr journals library Southampton 2046-4924
PY  - 2016
SP  - I-450
T2  - Health Technology Assessment
TI  - Clinical effectiveness and patient perspectives of different treatment strategies for tics in children and adolescents with Tourette syndrome: a systematic review and qualitative analysis
UR  - &lt;Go to ISI&gt;://WOS:000369106600001
VL  - 20
ER  -
TY  - JOUR
AB  - **Objectives. **
To update a prior systematic review on the effects of omega-3 fatty acids (n-3 FA) on maternal and child health and to assess the evidence for their effects on, and associations with, additional outcomes.

**Data sources. **
MEDLINE&reg;, Embase&reg;, the Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Centre for Agriculture and Biosciences (CAB) Abstracts from 2000 to August 2015; eligible studies from the original report; and relevant systematic reviews.

**Review methods. **
We included randomized controlled trials (RCTs) of any defined dose of n-3 FA (or combination) compared to placebo, any other n-3 FA, or alternative dose with an outcome of interest conducted in pregnant or breastfeeding women or neonates (preterm or term). We also included prospective observational studies that analyzed the association between baseline n-3 FA intake or biomarker level and followup outcomes. Postnatal interventions began within a week of birth for term infants and within a week of beginning enteral or oral feeding for preterm infants. Standard methods were used for data abstraction and analysis, according to the Evidence-based Practice Center Methods Guide.

**Results. **
We identified 4,275 potentially relevant titles from our searches, of which 95 RCTs and 48 observational studies met the inclusion criteria. Risk of bias was a concern with both RCTs and observational studies. Outcomes for which evidence was sufficient to draw a conclusion are summarized here with the Strength of Evidence (SoE). (Outcomes for which the evidence was insufficient to draw a conclusion are summarized in Appendix G of the report.)

**Maternal Exposures and Outcomes**

Gestational length and risk for preterm birth: Prenatal algal docosahexaenoic acid (DHA) or DHA-enriched fish oil supplementation had a small positive effect on length of gestation (moderate SoE), but no effect on risk for preterm birth (low SoE).  Prenatal EPA (eicosapentaenoic acid) plus DHA-containing fish oil supplementation has no effect on length of gestation (low SoE). Supplementation with DHA, or EPA plus DHA-, or DHA-enriched fish oil does not decreaserisk for preterm birth (low SoE).

Birth weight and risk for low birth weight: Changes in maternal n-3 FA biomarkers were significantly associated with birth weight. Prenatal algal DHA or DHA-enriched fish oil supplementation had a positive effect on birth weight among healthy term infants (moderate SoE), but prenatal DHA supplementation had no effect on risk for low birth weight (low SoE).  Prenatal EPA plus DHA or alpha-linolenic acid (ALA) supplementation had no effect on birth weight (low SoE).

Risk for peripartum depression: Maternal n-3 FA biomarkers had no association with risk for peripartum depression. Maternal DHA, EPA, or DHA-enriched fish oil supplementation had no effect on risk for peripartum depression (low SoE).

Risk for gestational hypertension/preeclampsia: Prenatal DHA supplementation among high-risk pregnant women had no effect on the risk for gestational hypertension or preeclampsia (moderate SoE). Prenatal supplementation of any n-3 FA in normal-risk women also had no significant effect on risk for gestational hypertension or preeclampsia (low SoE).

**Fetal, Infant, and Child Exposures and Outcomes**

Postnatal growth patterns: Maternal fish oil or DHA plus EPA supplementation had no effect on postnatal growth patterns (attainment of weight, length, and head circumference) when administered prenatally (moderate SoE) or both pre- and postnatally (low SoE). Fortification of infant formulas with DHA plus arachidonic acid (AA, an n-6 FA) had no effect on growth patterns of preterm or term infants (low SoE).

Visual acuity: Prenatal supplementation with DHA had no effect on development of visual acuity (low SoE). Supplementing or fortifying preterm infant formula with any n-3 FA had no significant effect on visual acuity assessed by visual evoked potentials (VEP) at 4 or 6 months corrected age (low SoE).  Data conflicted on the effectiveness of supplementing infant formula for term infants with n-3 FA depending on when and how visual acuity was assessed (i.e. by VEP or by behavioral methods) and the type of essential FA provided (low SoE).

Neurological development: Prenatal or postnatal  n-3 FA supplementation had no consistent effect on neurological development (low SoE).

Cognitive development: Prenatal DHA supplementation with AA or EPA had no effect on cognitive development (moderate SoE). Supplementing breastfeeding women with DHA plus EPA  also had no effect on cognitive development in infants and children (low SoE). Supplementing or fortifying preterm infants&rsquo; formula with DHA plus AA had a positive effect on infant cognition at some short-term followup times (moderate SoE). Supplementing or fortifying infant formula for term infants with any n-3 FA had no effect on cognitive development (low SoE). Evidence is insufficient to support any effect of n-3 FA infant supplementation on long-term cognitive outcomes.

Autism spectrum disorder, attention deficit hyperactivity disorder (ADHD), and learning disorders: Maternal or infant n-3 FA supplementation had no effect on risk for autism spectrum disorders or ADHD (low SoE). No studies on other learning disorders were identified.

Atopic dermatitis (AD), allergies, and respiratory disorders: Pre- and postnatal (maternal and infant) n-3 FA supplementation had no consistent effect on the risk for AD/eczema, allergies, asthma, and other respiratory illnesses (moderate SoE). Biomarkers and intakes had no consistent association with the risk for AD, allergies, and respiratory disorders (low SoE).   

Adverse events: Prenatal and infant supplementation with n-3 FA or fortification of foods with n-3 FA did not result in any serious or nonserious adverse events (moderate SoE); with the exception of an increased risk for mild gastrointestinal symptoms.

Conclusions. 
Most studies in this report examined the effects of fish oil (or other combinations of DHA and EPA) supplements on pregnant or breastfeeding women or the effects of infant formula fortified with DHA plus AA. As with the original report, with the exception of small increases in birth weight and length of gestation,n-3 FA supplementation or fortification has no consistent evidence of effects on peripartum maternal or infant health outcomes. No effects of n-3 FA were seen on gestational hypertension, peripartum depression, or postnatal growth. Apparent effects of n-3 FA supplementation were inconsistent across assessment methods and followup times for outcomes related to infant visual acuity, cognitive development and prevention of allergy and asthma. Future RCTs need to assess standardized preparations of n-3 and n-6 FA, using a select group of clinically important outcomes, on populations with baseline n-3 FA intakes typical of those of most western populations.
AD  - Newberry, Sydne J. Southern California Evidence-based Practice Center.Chung, Mei. Southern California Evidence-based Practice Center.Booth, Marika. Southern California Evidence-based Practice Center.Maglione, Margaret A. Southern California Evidence-based Practice Center.Tang, Alice M. Southern California Evidence-based Practice Center.O&#039;Hanlon, Claire E. Southern California Evidence-based Practice Center.Wang, Ding Ding. Southern California Evidence-based Practice Center.Okunogbe, Adeyemi. Southern California Evidence-based Practice Center.Huang, Christina. Southern California Evidence-based Practice Center.Motala, Aneesa. Southern California Evidence-based Practice Center.Trimmer, Martha. Southern California Evidence-based Practice Center.Dudley, Whitney. Southern California Evidence-based Practice Center.Shanman, Roberta. Southern California Evidence-based Practice Center.Coker, Tumaini R. Southern California Evidence-based Practice Center.Shekelle, Paul G. Southern California Evidence-based Practice Center.
AN  - 30307735
AU  - Newberry,
AU  - S.
AU  - J.
AU  - Chung,
AU  - M.
AU  - Booth,
AU  - M.
AU  - Maglione,
AU  - M.
AU  - A.
AU  - Tang,
AU  - A.
AU  - M.
AU  - O&#039;Hanlon,
AU  - C.
AU  - E.
AU  - Wang,
AU  - D.
AU  - D.
AU  - Okunogbe,
AU  - A.
AU  - Huang,
AU  - C.
AU  - Motala,
AU  - A.
AU  - Trimmer,
AU  - M.
AU  - Dudley,
AU  - W.
AU  - Shanman,
AU  - R.
AU  - Coker,
AU  - T.
AU  - R.
AU  - Shekelle,
AU  - P.
AU  - G.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.23970/AHRQEPCERTA224
DP  - Ovid Technologies
J2  - Evid rep/technol assess
L1  - internal-pdf://3047205786/Newberry-2016-Omega-3 Fatty Acids and Maternal.pdf
LA  - English
M3  - Review
N1  - Newberry, Sydne JChung, MeiBooth, MarikaMaglione, Margaret ATang, Alice MO&#039;Hanlon, Claire EWang, Ding DingOkunogbe, AdeyemiHuang, ChristinaMotala, AneesaTrimmer, MarthaDudley, WhitneyShanman, RobertaCoker, Tumaini RShekelle, Paul G
PY  - 2016
SP  - 1-826
T2  - Evidence Report/Technology Assessment
TI  - Omega-3 Fatty Acids and Maternal and Child Health: An Updated Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=30307735
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:30307735&amp;id=doi:10.23970%2FAHRQEPCERTA224&amp;issn=1530-4396&amp;isbn=&amp;volume=&amp;issue=224&amp;spage=1&amp;pages=1-826&amp;date=2016&amp;title=Evidence+Report%2FTechnology+Assessment&amp;atitle=Omega-3+Fatty+Acids+and+Maternal+and+Child+Health%3A+An+Updated+Systematic+Review.&amp;aulast=Newberry&amp;pid=%3Cauthor%3ENewberry+SJ%3C%2Fauthor%3E%3CAN%3E30307735%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Background: **
Evidence of treatment foster care (TFC) and group care&#039;s (GC) potential to prevent delinquency and crime has been developing. 

**Objectives: **
We clarified the state of comparative knowledge with a historical overview. Then we explored the hypothesis that smaller, probably better resourced group homes with smaller staff/resident ratios have greater impacts than larger homes with a meta-analytic update. 

**Methods: **
Research literatures were searched to 2015. Five systematic reviews were selected that included seven independent studies that compared delinquency or crime outcomes among youths ages 10-18. A similar search augmented by author and bibliographic searches identified six additional studies with an updated meta-analysis. Discrete effects were analyzed with sample-weighted preventive fractions (PF) and 95 % confidence intervals (CI). 

**Results: **
Compared with GC, TFC was estimated to prevent nearly half of delinquent or criminal acts over 1-3 years (PF = 0.56, 95 % CI 0.50, 0.64). Two pooled study outcomes tentatively suggested that GC in homes with less than ten youths may prevent delinquency and crime better than TFC, p = 0.08. Study designs were non-equivalent or randomized trials that were typically too small to ensure controlled comparisons. 

**Conclusions: **
These synthetic findings are best thought of as preliminary hypotheses. Confident knowledge will require their testing with large, perhaps multisite, controlled trials. Such a research agenda will undoubtedly be quite expensive, but it holds the promise of knowledge dividends that could prevention much suffering among youths, their families and society. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Gorey, Kevin M.: gorey@uwindsor.ca Gorey, Kevin M.: School of Social Work, University of Windsor, 401 Windsor Avenue, Windsor, ON, Canada, N9B 3P4, gorey@uwindsor.ca Osei, Gershon K.: School of Social Work, University of Windsor, Windsor, ON, Canada Gorey, Kevin M.: School of Social Work, University of Windsor, Windsor, ON, Canada Hernandez Jozefowicz, Debra M.: School of Social Work, University of Windsor, Windsor, ON, Canada
AN  - 2015-15557-001
AU  - Osei,
AU  - G.
AU  - K.
AU  - Gorey,
AU  - K.
AU  - M.
AU  - Hernandez
AU  - Jozefowicz,
AU  - D.
AU  - M.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10566-015-9315-0
DP  - Ovid Technologies
KW  - Treatment foster care, Group care, Delinquency, Crime, Overview, Meta-analysis
KW  - *Community Services
KW  - *Crime Prevention
KW  - *Foster Care
KW  - *Juvenile Delinquency
KW  - *Group Intervention
KW  - Criminal Behavior &amp; Juvenile Delinquency [3236]
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human Childhood (birth-12 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older) Young Adulthood (18-29 yrs)
L1  - internal-pdf://1117821524/ChildYouthCareForum2015.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 33-46
T2  - Child and Youth Care Forum
TI  - Delinquency and crime prevention: Overview of research comparing treatment foster care and group care
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2015-15557-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10566-015-9315-0&amp;issn=1053-1890&amp;isbn=&amp;volume=45&amp;issue=1&amp;spage=33&amp;pages=33-46&amp;date=2016&amp;title=Child+%26+Youth+Care+Forum&amp;atitle=Delinquency+and+crime+prevention%3A+Overview+of+research+comparing+treatment+foster+care+and+group+care.&amp;aulast=Osei&amp;pid=%3Cauthor%3EOsei%2C+Gershon+K%3C%2Fauthor%3E%3CAN%3E2015-15557-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 45
ER  -
TY  - JOUR
AB  - **Background: **
Postnatal depression (PND) is a major depressive disorder in the year following childbirth, which impacts on women, their infants and their families. A range of interventions has been developed to prevent PND. 

**Objectives: **
To (1) evaluate the clinical effectiveness, cost-effectiveness, acceptability and safety of antenatal and postnatal interventions for pregnant and postnatal women to prevent PND; (2) apply rigorous methods of systematic reviewing of quantitative and qualitative studies, evidence synthesis and decision-analytic modelling to evaluate the preventive impact on women, their infants and their families; and (3) estimate cost-effectiveness. 

**Data sources: **
We searched MEDLINE, EMBASE, Science Citation Index and other databases (from inception to July 2013) in December 2012, and we were updated by electronic alerts until July 2013. 

**Review methods: **
Two reviewers independently screened titles and abstracts with consensus agreement. We undertook quality assessment. All universal, selective and indicated preventive interventions for pregnant women and women in the first 6 postnatal weeks were included. All outcomes were included, focusing on the Edinburgh Postnatal Depression Scale (EPDS), diagnostic instruments and infant outcomes. The quantitative evidence was synthesised using network meta-analyses (NMAs). A mathematical model was constructed to explore the cost-effectiveness of interventions contained within the NMA for EPDS values. 

**Results: **
From 3072 records identified, 122 papers (86 trials) were included in the quantitative review. From 2152 records, 56 papers (44 studies) were included in the qualitative review. The results were inconclusive. The most beneficial interventions appeared to be midwifery redesigned postnatal care [ as shown by the mean 12-month EPDS score difference of -1.43 (95% credible interval -4.00 to 1.36)], person-centred approach (PCA)-based and cognitive-behavioural therapy (CBT)-based intervention (universal), interpersonal psychotherapy (IPT)-based intervention and education on preparing for parenting (selective), promoting parent-infant interaction, peer support, IPT-based intervention and PCA-based and CBT-based intervention (indicated). Women valued seeing the same health worker, the involvement of partners and access to several visits from a midwife or health visitor trained in person-centred or cognitive-behavioural approaches. The most cost-effective interventions were estimated to be midwifery redesigned postnatal care (universal), PCA-based intervention (indicated) and IPT-based intervention in the sensitivity analysis (indicated), although there was considerable uncertainty. Expected value of partial perfect information (EVPPI) for efficacy data was in excess of 150M pound for each population. Given the EVPPI values, future trials assessing the relative efficacies of promising interventions appears to represent value for money. 

**Limitations: **
In the NMAs, some trials were omitted because they could not be connected to the main network of evidence or did not provide EPDS scores. This may have introduced reporting or selection bias. No adjustment was made for the lack of quality of some trials. Although we appraised a very large number of studies, much of the evidence was inconclusive. 

**Conclusions: **
Interventions warrant replication within randomised controlled trials (RCTs). Several interventions appear to be cost-effective relative to usual care, but this is subject to considerable uncertainty. 

**Future work recommendations: **
Several interventions appear to be cost-effective relative to usual care, but this is subject to considerable uncertainty. Future research conducting RCTs to establish which interventions are most clinically effective and cost-effective should be considered.
AD  - [Morrell, C. Jane; Spiby, Helen] Univ Nottingham, Sch Hlth Sci, Nottingham NG7 2RD, England. [Sutcliffe, Paul; Ragonesi, Margherita; Stewart-Brown, Sarah] Univ Warwick, Warwick Med Sch, Div Hlth Sci, Coventry CV4 7AL, W Midlands, England. [Booth, Andrew; Stevens, John; Scope, Alison; Stevenson, Matt; Harvey, Rebecca; Bessey, Alice; Cantrell, Anna; Ren, Shijie] Univ Sheffield, Sch Hlth &amp; Related Res, Sheffield, S Yorkshire, England. [Dennis, Cindy-Lee] Univ Toronto, Lawrence S Bloomberg Fac Nursing, Toronto, ON, Canada. [Barkham, Michael] Univ Sheffield, Dept Psychol, Clin Psychol Unit, Sheffield S10 2TN, S Yorkshire, England. [Churchill, Dick] Univ Nottingham, Sch Med, Nottingham, England. [Henshaw, Carol] Univ Liverpool, Inst Psychol Hlth &amp; Soc, Div Psychiat, Liverpool L69 3BX, Merseyside, England. [Newstead, Jo] Nottingham Experts Patients Grp, Clin Reference Grp Perinatal Mental Hlth, Nottingham, England. [Slade, Pauline] Univ Liverpool, Inst Psychol Hlth &amp; Soc, Liverpool L69 3BX, Merseyside, England. Morrell, CJ (reprint author), Univ Nottingham, Sch Hlth Sci, Nottingham NG7 2RD, England.
AN  - WOS:000376889600001
AU  - Morrell,
AU  - C.
AU  - J.
AU  - Sutcliffe,
AU  - P.
AU  - Booth,
AU  - A.
AU  - Stevens,
AU  - J.
AU  - Scope,
AU  - A.
AU  - Stevenson,
AU  - M.
AU  - Harvey,
AU  - R.
AU  - Bessey,
AU  - A.
AU  - Cantrell,
AU  - A.
AU  - Dennis,
AU  - C.
AU  - L.
AU  - Ren,
AU  - S.
AU  - J.
AU  - Ragonesi,
AU  - M.
AU  - Barkham,
AU  - M.
AU  - Churchill,
AU  - D.
AU  - Henshaw,
AU  - C.
AU  - Newstead,
AU  - J.
AU  - Slade,
AU  - P.
AU  - Spiby,
AU  - H.
AU  - Stewart-Brown,
AU  - S.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3310/hta20370
J2  - Health Technol. Assess.
KW  - randomized-controlled-trial
KW  - group prenatal-care
KW  - black caribbean women
KW  - brief interpersonal psychotherapy
KW  - treat postpartum depression
KW  - placebo-controlled trial
KW  - middle-income countries
KW  - routine primary-care
KW  - 2 urban clinics
KW  - perinatal depression
KW  - Health Care Sciences &amp; Services
L1  - internal-pdf://0058622802/3003418.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DN2JJ Times Cited: 1 Cited Reference Count: 478 Morrell, C. Jane Sutcliffe, Paul Booth, Andrew Stevens, John Scope, Alison Stevenson, Matt Harvey, Rebecca Bessey, Alice Cantrell, Anna Dennis, Cindy-Lee Ren, Shijie Ragonesi, Margherita Barkham, Michael Churchill, Dick Henshaw, Carol Newstead, Jo Slade, Pauline Spiby, Helen Stewart-Brown, Sarah Barkham, Michael/0000-0003-1687-6376 National Institute for Health Research Health Technology Assessment programme The National Institute for Health Research Health Technology Assessment programme. 1 21 25 Nihr journals library Southampton 2046-4924
PY  - 2016
SP  - 1-+
T2  - Health Technology Assessment
TI  - A systematic review, evidence synthesis and meta-analysis of quantitative and qualitative studies evaluating the clinical effectiveness, the cost-effectiveness, safety and acceptability of interventions to prevent postnatal depression
UR  - &lt;Go to ISI&gt;://WOS:000376889600001
VL  - 20
ER  -
TY  - JOUR
AB  - **IMPORTANCE: **
Although attention-deficit/hyperactivity disorder (ADHD) is highly prevalent in adolescents and often persists into adulthood, most studies about treatment were performed in children. Less is known about ADHD treatment in adolescents. 

**OBJECTIVE: **
To review the evidence for pharmacological and psychosocial treatment of ADHD in adolescents. 

**EVIDENCE REVIEW: **
The databases of CINAHL Plus, MEDLINE, PsycINFO, ERIC, and the Cochrane Database of Systematic Reviews were searched for articles published between January 1, 1999, and January 31, 2016, on ADHD treatment in adolescents. Additional studies were identified by hand-searching reference lists of retrieved articles. Study quality was rated using McMaster University Effective Public Health Practice Project criteria. The evidence level for treatment recommendations was based on Oxford Centre for Evidence-Based Medicine criteria. 

**FINDINGS: **
Sixteen randomized clinical trials and 1 meta-analysis, involving 2668 participants, of pharmacological and psychosocial treatments for ADHD in adolescents aged 12 years to 18 years were included. Evidence of efficacy was stronger for the extended-release methylphenidate and amphetamine class stimulant medications (level 1B based on Oxford Centre for Evidence-Based Medicine criteria) and atomoxetine than for the extended-release alpha2-adrenergic agonists guanfacine or clonidine (no studies). For the primary efficacy measure of total symptom score on the ADHD Rating Scale (score range, 0 [least symptomatic] to 54 [most symptomatic]), both stimulant and nonstimulant medications led to clinically significant reductions of 14.93 to 24.60 absolute points. The psychosocial treatments combining behavioral, cognitive behavioral, and skills training techniques demonstrated small- to medium-sized improvements (range for mean SD difference in Cohen d, 0.30-0.69) for parent-rated ADHD symptoms, co-occurring emotional or behavioral symptoms, and interpersonal functioning. Psychosocial treatments were associated with more robust (Cohen d range, 0.51-5.15) improvements in academic and organizational skills, such as homework completion and planner use. 

**CONCLUSIONS AND RELEVANCE: **
Evidence supports the use of extended-release methylphenidate and amphetamine formulations, atomoxetine, and extended-release guanfacine to improve symptoms of ADHD in adolescents. Psychosocial treatments incorporating behavior contingency management, motivational enhancement, and academic, organizational, and social skills training techniques were associated with inconsistent effects on ADHD symptoms and greater benefit for academic and organizational skills. Additional treatment studies in adolescents, including combined pharmacological and psychosocial treatments, are needed.
AD  - Chan, Eugenia. Division of Developmental Medicine, Boston Children&#039;s Hospital, Boston, Massachusetts3Harvard Medical School, Boston, Massachusetts. Fogler, Jason M. Division of Developmental Medicine, Boston Children&#039;s Hospital, Boston, Massachusetts2Department of Psychiatry, Boston Children&#039;s Hospital, Boston, Massachusetts3Harvard Medical School, Boston, Massachusetts. Hammerness, Paul G. Department of Psychiatry, Boston Children&#039;s Hospital, Boston, Massachusetts3Harvard Medical School, Boston, Massachusetts.
AN  - 27163988
AU  - Chan,
AU  - E.
AU  - Fogler,
AU  - J.
AU  - M.
AU  - Hammerness,
AU  - P.
AU  - G.
DA  - May 10
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1001/jama.2016.5453
DP  - Ovid Technologies
J2  - Jama
KW  - Adolescent
KW  - Adrenergic alpha-2 Receptor Agonists/tu [Therapeutic Use]
KW  - Amphetamines/tu [Therapeutic Use]
KW  - Atomoxetine Hydrochloride/tu [Therapeutic Use]
KW  - Attention Deficit Disorder with Hyperactivity/px [Psychology]
KW  - *Attention Deficit Disorder with Hyperactivity/th [Therapy]
KW  - *Central Nervous System Stimulants/tu [Therapeutic Use]
KW  - Clonidine/tu [Therapeutic Use]
KW  - Delayed-Action Preparations/tu [Therapeutic Use]
KW  - Guanfacine/tu [Therapeutic Use]
KW  - Humans
KW  - Methylphenidate/tu [Therapeutic Use]
KW  - Motivation
KW  - *Psychotherapy/mt [Methods]
KW  - Randomized Controlled Trials as Topic
KW  - Social Skills
KW  - 0 (Adrenergic alpha-2 Receptor Agonists)
KW  - 0 (Amphetamines)
KW  - 0 (Central Nervous System Stimulants)
KW  - 0 (Delayed-Action Preparations)
KW  - 207ZZ9QZ49 (Methylphenidate)
KW  - 30OMY4G3MK (Guanfacine)
KW  - 57WVB6I2W0 (Atomoxetine Hydrochloride)
KW  - MN3L5RMN02 (Clonidine)
L1  - internal-pdf://1663413057/Chan-2016-Treatment of Attention-Deficit_Hyper.pdf
LA  - English
M3  - Review
N1  - Chan, Eugenia Fogler, Jason M Hammerness, Paul G 2520634
PY  - 2016
SP  - 1997-2008
T2  - JAMA
TI  - Treatment of Attention-Deficit/Hyperactivity Disorder in Adolescents: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=27163988http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27163988&amp;id=doi:10.1001%2Fjama.2016.5453&amp;issn=0098-7484&amp;isbn=&amp;volume=315&amp;issue=18&amp;spage=1997&amp;pages=1997-2008&amp;date=2016&amp;title=JAMA&amp;atitle=Treatment+of+Attention-Deficit%2FHyperactivity+Disorder+in+Adolescents%3A+A+Systematic+Review.&amp;aulast=Chan&amp;pid=%3Cauthor%3EChan+E%3C%2Fauthor%3E%3CAN%3E27163988%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://jama.jamanetwork.com/pdfaccess.ashx?url=/data/journals/jama/935276/jrv160011.pdf
VL  - 315
ER  -
TY  - JOUR
AB  - Anecdotal evidence suggests that care farming practices have the potential to provide positive outcomes for young people in foster-care and residential care environments. 

A systematic review (searching; CINAHL, Web of Knowledge, PsychInfo) was conducted to explore how participation in care farming initiatives impacts attachment in children in foster-care and what aspects of care farming initiatives provides positive attachment outcomes. 

The systematic review did not identify any research publication in care farming and foster-care. 

Therefore, it is imperative that practitioners realise that the evidence is lacking when using these types of interventions and keep a close account of the benefit and harms that may be encountered during the interaction processes.
AD  - Downes, Martin J. Centre for Applied Health Economics, Griffith University, Queensland, Australia. Lakhani, Ali. School of Human Services and Social Work, Griffith University, Queensland, Australia. Maujean, Annick. CONROD, Griffith University, Queensland, Australia. Macfarlane, Kym. School of Human Services and Social Work, Griffith University, Queensland, Australia. Kendall, Elizabeth. School of Human Services and Social Work, Griffith University, Queensland, Australia.
AN  - 27559225
AU  - Downes,
AU  - M.
AU  - J.
AU  - Lakhani,
AU  - A.
AU  - Maujean,
AU  - A.
AU  - Macfarlane,
AU  - K.
AU  - Kendall,
AU  - E.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1093/bjsw/bcv070
DP  - Ovid Technologies
J2  - Br J Soc Work
L1  - internal-pdf://2269171446/Downes-2016-Evidence for Using Farm Care Pract.pdf
LA  - English
N1  - Downes, Martin J Lakhani, Ali Maujean, Annick Macfarlane, Kym Kendall, Elizabeth bcv070
PY  - 2016
SP  - 1241-1248
T2  - British Journal of Social Work
TI  - Evidence for Using Farm Care Practices to Improve Attachment Outcomes in Foster Children: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=27559225http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27559225&amp;id=doi:10.1093%2Fbjsw%2Fbcv070&amp;issn=0045-3102&amp;isbn=&amp;volume=46&amp;issue=5&amp;spage=1241&amp;pages=1241-1248&amp;date=2016&amp;title=British+Journal+of+Social+Work&amp;atitle=Evidence+for+Using+Farm+Care+Practices+to+Improve+Attachment+Outcomes+in+Foster+Children%3A+A+Systematic+Review.&amp;aulast=Downes&amp;pid=%3Cauthor%3EDownes+MJ%3C%2Fauthor%3E%3CAN%3E27559225%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985735/pdf/bcv070.pdf
VL  - 46
ER  -
TY  - JOUR
AB  - **Objective: **
Given depression is a significant risk factor for suicidal behaviour, it is possible that interventions for depression may also reduce the risk of suicide in adolescents. The purpose of this literature review is to determine whether psychological interventions aimed to prevent and/or treat depression in adolescents can also reduce suicidality. 

**Methods: **
We conducted a systematic review of psychological interventions aimed to prevent and/or treat depression in adolescents in which outcomes for suicidality were reported, using five databases: PsycINFO, Embase, Medline, CINAHL and Scopus. Study quality was assessed using the Cochrane Collaboration&#039;s tool for assessing risk of bias. 

**Results:** 
A total of 35 articles pertaining to 12 treatment trials, two selective prevention trials and two universal prevention trials met inclusion criteria. No studies were identified that used a no-treatment control. In both intervention and active control groups, suicidality decreased over time; however, most structured psychological depression treatment interventions did not outperform pharmaceutical or treatment as usual control groups. Depression prevention studies demonstrated small but statistically significant reductions in suicidality. 

**Limitations: **
Analysis of study quality suggested that at least 10 of the 16 studies have a high risk of bias. Conclusive comparisons across studies are problematic due to differences in measures, interventions, population differences and control groups used. 

**Conclusions: **
It is unclear whether psychological treatments are more effective than no treatment since no study has used a no-treatment control group. There is evidence to suggest that Cognitive Behavioural Therapy interventions produce pre post reductions in suicidality with moderate effect sizes and are at least as efficacious as pharmacotherapy in reducing suicidality; however, it is unclear whether these effects are sustained. There are several trials showing promising evidence for family-based and interpersonal therapies, with large pre post effect sizes, and further evaluation with improved methodology is required. Depression prevention interventions show promising short-term effects.
AD  - [Devenishi, Bethany; Berki, Lesley; Lewis, Andrew J.] Deakin Univ, Sch Psychol, Fac Hlth, Burwood, Australia. [Berki, Lesley] Deakin Univ, Fac Med Dent &amp; Hlth Sci, Dept Psychiat, Burwood, Australia. [Lewis, Andrew J.] Murdoch Univ, Sch Psychol &amp; Exercise Sci, 90 South St, Murdoch, WA 6011, Australia. Lewis, AJ (reprint author), Murdoch Univ, Sch Psychol &amp; Exercise Sci, 90 South St, Murdoch, WA 6011, Australia. a.lewis@murdoch.edu.au
AN  - WOS:000381656400005
AU  - Devenishi,
AU  - B.
AU  - Berki,
AU  - L.
AU  - Lewis,
AU  - A.
AU  - J.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0004867415627374
J2  - Aust. N. Z. J. Psych.
KW  - Suicide
KW  - adolescents
KW  - depression
KW  - systematic review
KW  - treatment
KW  - randomized controlled-trial
KW  - cognitive-behavioral therapy
KW  - ssri-resistant depression
KW  - clinical psychotherapy trial
KW  - young-people
KW  - prevention program
KW  - mental-disorders
KW  - social support
KW  - family-therapy
KW  - risk-factors
KW  - Psychiatry
L1  - internal-pdf://3370369666/Devenishi-2016-The treatment of suicidality in.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DT7GZ Times Cited: 0 Cited Reference Count: 74 Devenishi, Bethany Berki, Lesley Lewis, Andrew J. Lewis, Andrew/0000-0002-2519-7976 0 12 Sage publications ltd London 1440-1614
PY  - 2016
SP  - 726-740
T2  - Australian and New Zealand Journal of Psychiatry
TI  - The treatment of suicidality in adolescents by psychosocial interventions for depression: A systematic literature review
UR  - &lt;Go to ISI&gt;://WOS:000381656400005
VL  - 50
ER  -
TY  - JOUR
AB  - **AIMS: **
Motivational interviewing (MI) is a commonly used intervention approach to promote reduction or cessation of substance abuse. Effects may be different for adolescents, so it is useful to assess the state of the evidence in this subpopulation. This paper aimed to assess evidence for MI effectiveness in adolescents. 

**METHOD:**
EBSCOhost, ProQuest and Digital Dissertation Consortium were searched using keywords. Ten randomized trials from the United Kingdom, United States and Taiwan, including 1466 participants, were identified and analysed using a random effects model. Primary outcome measures captured were: the extent of drug use, intention to use drugs and readiness to change. Each study received a high-quality score based on the Miller Quality Scoring Coding System. Moderator analyses were also conducted to examine the impacts of follow-up period, delivery setting and study design on the effectiveness of MI. 

**RESULTS: **
No statistically significant effect of MI on was found change of drug use behaviours [d = 0.05, 95% confidence interval (CI) = -0.06, 0.17, P = 0.36]. A significant effect was found on attitude change (d = 0.44, 95% CI = 0.20, 0.67, P = 0.0002). The funnel plot was asymmetrical, suggesting publication bias favouring small studies with higher effect sizes. 

**CONCLUSION: **
Motivational interviewing has not been found thus far to reduce adolescent use of illicit drugs. It may influence intentions to change, but evidence of publication bias weakens confidence in this conclusion. 

Copyright &copy; 2015 Society for the Study of Addiction.
AD  - Li, Lili. Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong SAR, China. Zhu, Shimin. Department of Applied Social Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China. Tse, Nick. Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong SAR, China. Tse, Samson. Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong SAR, China. Wong, Paul. Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong SAR, China.
AN  - 26687544
AU  - Li,
AU  - L.
AU  - Zhu,
AU  - S.
AU  - Tse,
AU  - N.
AU  - Tse,
AU  - S.
AU  - Wong,
AU  - P.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/add.1328
DP  - Ovid Technologies
J2  - Addiction
KW  - Adolescent
KW  - Child
KW  - Feedback, Psychological
KW  - Female
KW  - Humans
KW  - Male
KW  - *Motivational Interviewing
KW  - Randomized Controlled Trials as Topic
KW  - Sample Size
KW  - *Street Drugs
KW  - *Substance-Related Disorders/rh [Rehabilitation]
KW  - Treatment Outcome
KW  - 0 (Street Drugs)
L1  - internal-pdf://0916994658/Li-2016-Effectiveness of motivational intervie.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Li, Lili Zhu, Shimin Tse, Nick Tse, Samson Wong, Paul
PY  - 2016
SP  - 795-805
T2  - Addiction
TI  - Effectiveness of motivational interviewing to reduce illicit drug use in adolescents: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26687544http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26687544&amp;id=doi:10.1111%2Fadd.13285&amp;issn=0965-2140&amp;isbn=&amp;volume=111&amp;issue=5&amp;spage=795&amp;pages=795-805&amp;date=2016&amp;title=Addiction&amp;atitle=Effectiveness+of+motivational+interviewing+to+reduce+illicit+drug+use+in+adolescents%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Li&amp;pid=%3Cauthor%3ELi+L%3C%2Fauthor%3E%3CAN%3E26687544%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1111/add.13285/asset/add13285.pdf?v=1&amp;t=j02f6cjl&amp;s=bd1e931d5142576bd2ede508979b314c191c036e
VL  - 111
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Increasing numbers of youth in need of emergency medical treatment following alcohol intoxication have been a major public health concern in Europe in recent years. Brief interventions (BIs) in the emergency department (ED) could prevent future risky drinking. However, effectiveness and feasibility of this approach are currently unclear. 

**METHOD: **
A systematic literature search on controlled trials including participants aged 12-25 years treated in an ED following an alcohol-related event was conducted. Additionally, a grey literature search was conducted to support findings from the systematic review with evidence from practice projects and uncontrolled trials. Data on effectiveness, acceptance, implementation and reach were extracted. 

**RESULTS: **
Seven randomised controlled trials (RCT), 6 practice projects, 1 non-randomised pilot study and 1 observational study were identified. Six RCTs found reductions of alcohol use for all participants. Four RCTs found effects on alcohol consumption, alcohol-related risk-behaviour or referral to treatment. Participation and referral rates varied strongly, whereas data on acceptance and implementation were rarely assessed. 

**CONCLUSION: **
Heterogeneity of study designs and effects limit conclusions on effectiveness of BIs for young ED patients following an alcohol-related event. However, the number of practice projects in Europe indicates a need perceived by practitioners to address this population. 

Copyright &copy; 2015 S. Karger AG, Basel.
AD  - Diestelkamp, Silke. German Center for Addiction Research in Childhood and Adolescence, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
AN  - 26314693
AU  - Diestelkamp,
AU  - S.
AU  - Drechsel,
AU  - M.
AU  - Baldus,
AU  - C.
AU  - Wartberg,
AU  - L.
AU  - Arnaud,
AU  - N.
AU  - Thomasius,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1159/000435877
DP  - Ovid Technologies
J2  - Eur Addict Res
KW  - Adolescent
KW  - Adult
KW  - *Alcoholism/pc [Prevention &amp; Control]
KW  - Child
KW  - *Emergency Medical Services/mt [Methods]
KW  - Humans
KW  - *Psychotherapy, Brief/mt [Methods]
KW  - Young Adult
L1  - internal-pdf://1133823532/document.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Diestelkamp, Silke Drechsel, Magdalena Baldus, Christiane Wartberg, Lutz Arnaud, Nicolas Thomasius, Rainer 000435877
PY  - 2016
SP  - 17-35
T2  - European Addiction Research
TI  - Brief in Person Interventions for Adolescents and Young Adults Following Alcohol-Related Events in Emergency Care: A Systematic Review and European Evidence Synthesis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26314693http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26314693&amp;id=doi:10.1159%2F000435877&amp;issn=1022-6877&amp;isbn=&amp;volume=22&amp;issue=1&amp;spage=17&amp;pages=17-35&amp;date=2016&amp;title=European+Addiction+Research&amp;atitle=Brief+in+Person+Interventions+for+Adolescents+and+Young+Adults+Following+Alcohol-Related+Events+in+Emergency+Care%3A+A+Systematic+Review+and+European+Evidence+Synthesis.&amp;aulast=Diestelkamp&amp;pid=%3Cauthor%3EDiestelkamp+S%3C%2Fauthor%3E%3CAN%3E26314693%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 22
ER  -
TY  - JOUR
AB  - A meta-analytic study, involving 14 controlled studies (N=88495 participants), was conducted to examine the effectiveness of Family Group Conferencing (FGC) in youth care. Child safety (in terms of reports of child maltreatment and out-of-home placement) and involvement of youth care were included as outcome variables; study, sample and intervention characteristics were included as moderators. 

Overall, FGC did not significantly reduce child maltreatment, out-of-home placements, and involvement of youth care. Study and sample characteristics moderated the effectiveness of FGC. Retrospective studies found FGC to be more effective than regular care in reducing the recurrence of maltreatment and decreasing the number and length of out-of-home placements, whereas prospective studies found FGC to be not more effective than regular care. 

Moreover, FGC was found to increase the number and length of out-of-home placements for families with older children and minority groups. The findings of this study showed that robust research proving effectiveness of FGC is limited. It is, therefore, crucial for the safety and protection of children in youth care that, before broadly implementing this decision making model in youth care, more robust studies examining the effectiveness of FGC be conducted. 

Copyright A&copy; 2016 Elsevier Ltd. All rights reserved.
AD  - Dijkstra, Sharon. Forensic Child and Youth Care Sciences, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands. Electronic address: s.dijkstra@uva.nl. Creemers, Hanneke E. Forensic Child and Youth Care Sciences, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands. Electronic address: h.e.creemers@uva.nl. Asscher, Jessica J. Forensic Child and Youth Care Sciences, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands. Electronic address: j.j.asscher@uva.nl. Dekovic, Maja. Child and Adolescent Studies, Utrecht University, Heidelberglaan 1, 3584 CS, Utrecht, The Netherlands. Electronic address: m.dekovic@uu.nl. Stams, Geert Jan J M. Forensic Child and Youth Care Sciences, University of Amsterdam, Nieuwe Achtergracht 127, 1018 WS, Amsterdam, The Netherlands. Electronic address: g.j.j.m.stams@uva.nl.
AN  - 27810635
AU  - Dijkstra,
AU  - S.
AU  - Creemers,
AU  - H.
AU  - E.
AU  - Asscher,
AU  - J.
AU  - J.
AU  - Dekovic,
AU  - M.
AU  - Stams,
AU  - G.
AU  - J.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.chiabu.2016.10.017
DP  - Ovid Technologies
J2  - Child Abuse Negl
L1  - internal-pdf://1429522386/Dijkstra-2016-The effectiveness of family grou.pdf
LA  - English
N1  - Dijkstra, Sharon Creemers, Hanneke E Asscher, Jessica J Dekovic, Maja Stams, Geert Jan J M S0145-2134(16)30241-1
PY  - 2016
SP  - 100-110
T2  - Child Abuse &amp; Neglect
TI  - The effectiveness of family group conferencing in youth care: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27810635http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27810635&amp;id=doi:10.1016%2Fj.chiabu.2016.10.017&amp;issn=0145-2134&amp;isbn=&amp;volume=62&amp;issue=&amp;spage=100&amp;pages=100-110&amp;date=2016&amp;title=Child+Abuse+%26+Neglect&amp;atitle=The+effectiveness+of+family+group+conferencing+in+youth+care%3A+A+meta-analysis.&amp;aulast=Dijkstra&amp;pid=%3Cauthor%3EDijkstra+S%3C%2Fauthor%3E%3CAN%3E27810635%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0145213416302411/1-s2.0-S0145213416302411-main.pdf?_tid=b28df666-04c5-11e7-9b6b-00000aacb362&amp;acdnat=1489063461_2a6a461ceabf3e179fa622feec915907
VL  - 62
ER  -
TY  - JOUR
AB  - **Background: **
Dialectical behavior therapy (DBT) has proven effective in reducing symptoms and behaviors related to Borderline Personality Disorder. More recently, it has been modified and applied to adolescents struggling with regulating their emotions and who may engage in impulsive, self-destructive behaviors, including nonsuicidal self-injury (NSSI). However, there is limited research evidence regarding the effectiveness of DBT for reducing NSSI behavior and depression among adolescents. Given the high suicide risk associated with NSSI and its association with depression, this is clearly an important focus of clinical and research attention. 

**Method: **
This meta-analysis sought to offer preliminary evidence regarding the effectiveness of DBT to treat NSSI and depression in adolescents. Twelve published studies were included; all 12 reported pre- and post-treatment measures of depression and six of these studies reported pre- and post-treatment measures of NSSI. 

**Results: **
The weighted mean effect size for NSSI was large (g = 0.81, 95% CI = 0.59-1.03); the weighted mean effect size for depression was small (g = 0.36, 95% CI = 0.30-0.42). 

**Conclusions: **
Intervention effects for both outcomes were positive, suggesting decreased NSSI and improvement in depressive symptoms for adolescents following a course of DBT. However, given considerable limitations in the research base available for meta-analysis, these findings are preliminary and tentative. Limitations in the current knowledge base and suggestions for future research are discussed.

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Cook, Nathan E.: necook@mgh.harvard.edu Cook, Nathan E.: Massachusetts General Hospital, Department of Psychiatry, Learning and Emotional Assessment Program, 151 Merrimac Street 5th Floor, Boston, MA, US, 02114, necook@mgh.harvard.edu Cook, Nathan E.: Massachusetts General Hospital, Department of Psychiatry, Learning and Emotional Assessment Program, Boston, MA, US Gorraiz, Maggie: Center for Cognitive and Dialectical Behavior Therapy, Lake Success, NY, US
AN  - 2015-30870-001
AU  - Cook,
AU  - N.
AU  - E.
AU  - Gorraiz,
AU  - M.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/camh.12112
DP  - Ovid Technologies
KW  - Dialectical behavior therapy, depression, nonsuicidal self-injury, adolescents, meta-analysis
KW  - *Adolescent Development
KW  - *Major Depression
KW  - *Self-Injurious Behavior
KW  - *Dialectical Behavior Therapy
KW  - Behavior Therapy &amp; Behavior Modification [3312]
KW  - Human Adolescence (13-17 yrs)
L1  - internal-pdf://3792876227/Cook_et_al-2016-Child_and_Adolescent_Mental_He.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 81-89
T2  - Child and Adolescent Mental Health
TI  - Dialectical behavior therapy for nonsuicidal self-injury and depression among adolescents: Preliminary meta-analytic evidence
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2015-30870-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1111%2Fcamh.12112&amp;issn=1475-357X&amp;isbn=&amp;volume=21&amp;issue=2&amp;spage=81&amp;pages=81-89&amp;date=2016&amp;title=Child+and+Adolescent+Mental+Health&amp;atitle=Dialectical+behavior+therapy+for+nonsuicidal+self-injury+and+depression+among+adolescents%3A+Preliminary+meta-analytic+evidence.&amp;aulast=Cook&amp;pid=%3Cauthor%3ECook%2C+Nathan+E%3C%2Fauthor%3E%3CAN%3E2015-30870-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 21
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
A number of randomised controlled trials report a beneficial effect of omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation on emotional lability (EL) and related domains (e.g. oppositional behaviour, conduct problems). Given that n-3 PUFA supplementation shows a significant effect on reducing symptoms of attention-deficit/hyperactivity disorder (ADHD) and that EL and related behaviours commonly co-occurs with ADHD, it is important that there is a more conclusive picture as to the effect of n-3 PUFA on these co-occurring clinical domains. 

**METHODS: **
Databases (Ovid Medline, Embase, Psychinfo) were searched for trials assessing the effects of n-3 PUFA on EL, oppositional behaviour, aggression and conduct problems. We included trials in children who had ADHD or a related neurodevelopmental disorder.

**RESULTS:**
Of the 1775 identified studies, 10 were included in the meta-analysis. In the primary analyses n-3 PUFA supplementation did not show improvements in measures of EL, oppositional behaviour, conduct problems or aggression. However subgroup analyses of higher quality studies and those meeting strict inclusion criteria found a significant reduction in EL and oppositional behaviour. 

**LIMITATIONS: **
A number of treatment effects may have failed to reach statistical significance due to small sample sizes and within and between study heterogeneity in terms of design and study participants. 

**CONCLUSIONS: **
These results exclude the possibility of moderate to large effects. They provide suggestive evidence of small effects of n-3 PUFA on reducing EL and oppositional behaviour in subgroups of children with ADHD. 

Copyright &copy; 2015 Elsevier B.V. All rights reserved.
AD  - Cooper, Ruth E. King&#039;s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London SE5 8AF, UK. Electronic address: ruth.cooper@kcl.ac.uk. Tye, Charlotte. King&#039;s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London SE5 8AF, UK. Kuntsi, Jonna. King&#039;s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London SE5 8AF, UK. Vassos, Evangelos. King&#039;s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London SE5 8AF, UK. Asherson, Philip. King&#039;s College London, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, London SE5 8AF, UK.
AN  - 26551407
AU  - Cooper,
AU  - R.
AU  - E.
AU  - Tye,
AU  - C.
AU  - Kuntsi,
AU  - J.
AU  - Vassos,
AU  - E.
AU  - Asherson,
AU  - P.
DA  - Jan 15
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jad.2015.09.053
DP  - Ovid Technologies
J2  - J Affect Disord
KW  - *Affective Symptoms/dh [Diet Therapy]
KW  - Aggression/de [Drug Effects]
KW  - *Attention Deficit Disorder with Hyperactivity/dh [Diet Therapy]
KW  - *Attention Deficit Disorder with Hyperactivity/px [Psychology]
KW  - Dietary Supplements
KW  - *Emotions
KW  - *Fatty Acids, Omega-3/tu [Therapeutic Use]
KW  - Humans
KW  - *Problem Behavior
KW  - Randomized Controlled Trials as Topic
KW  - 0 (Fatty Acids, Omega-3)
L1  - internal-pdf://0481407871/Cooper-2016-The effect of omega-3 polyunsatura.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Cooper, Ruth E Tye, Charlotte Kuntsi, Jonna Vassos, Evangelos Asherson, Philip S0165-0327(15)30479-1
PY  - 2016
SP  - 474-82
T2  - Journal of Affective Disorders
TI  - The effect of omega-3 polyunsaturated fatty acid supplementation on emotional dysregulation, oppositional behaviour and conduct problems in ADHD: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26551407http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26551407&amp;id=doi:10.1016%2Fj.jad.2015.09.053&amp;issn=0165-0327&amp;isbn=&amp;volume=190&amp;issue=&amp;spage=474&amp;pages=474-82&amp;date=2016&amp;title=Journal+of+Affective+Disorders&amp;atitle=The+effect+of+omega-3+polyunsaturated+fatty+acid+supplementation+on+emotional+dysregulation%2C+oppositional+behaviour+and+conduct+problems+in+ADHD%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Cooper&amp;pid=%3Cauthor%3ECooper+RE%3C%2Fauthor%3E%3CAN%3E26551407%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0165032715304791/1-s2.0-S0165032715304791-main.pdf?_tid=b425f8b2-04c4-11e7-a982-00000aacb35d&amp;acdnat=1489063034_583a797d95e58a8729aa37c41493909c
VL  - 190
ER  -
TY  - JOUR
AB  - **BACKGROUND **
Pediatric obsessive-compulsive disorder (OCD) is a debilitating psychological anxiety disorder. Cognitive-behavioral therapy (CBT) has been shown to be an effective therapy for OCD, but the evaluation results from various studies are inconsistent and incomprehensive. This meta-analysis examined the efficacy of CBT in treatment of OCD. 

**MATERIAL AND METHODS **
A literature search identified 13 studies that met the inclusion criteria. The efficacy of CBT on OCD was evaluated by comparing post-treatment and pre-treatment Children&#039;s Yale-Brown Obsessive Compulsive Scale (CY-BOCS) scores. Weighted mean difference (WMD) was generated for the statistical evaluation. Heterogeneity was evaluated by I2 index. 

**RESULTS **
A decrease in WMD and a statistical significance (p&lt;0.0001) in both CY-BOCS and CGI scores between pre- and post-CBT treatment were observed in both overall database (-11.73) and USA subgroup (-11.371), which indicates a dramatic relief of OCD symptoms after CBT treatment. Heterogeneity was detected in overall database and USA subgroup, which resulted in an application of the random-effects model to both groups. Publication bias was examined by both Begg&#039;s funnel plot and Egger&#039;s test and no publication bias was detected. 

**CONCLUSIONS **
We concluded that CBT is efficacious in treating children&#039;s OCD.
AD  - Wu, Yanqiu. Department of Pathology, Yuhuangding Hospital, Yantai, Shandong, China (mainland). Lang, Zhiqiang. Department of Pathology, Yuhuangding Hospital, Yantai, Shandong, China (mainland). Zhang, Haitao. Department of Pathology, Yuhuangding Hospital, Yantai, Shandong, China (mainland).
AN  - 27182928
AU  - Wu,
AU  - Y.
AU  - Lang,
AU  - Z.
AU  - Zhang,
AU  - H.
DA  - May 16
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.12659/MSM.895481
DP  - Ovid Technologies
J2  - Med Sci Monit
L1  - internal-pdf://2879123602/Wu-2016-Efficacy of Cognitive-Behavioral Thera.pdf
LA  - English
N1  - Wu, Yanqiu Lang, Zhiqiang Zhang, Haitao 895481
PY  - 2016
SP  - 1646-53
T2  - Medical Science Monitor
TI  - Efficacy of Cognitive-Behavioral Therapy in Pediatric Obsessive-Compulsive Disorder: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27182928http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27182928&amp;id=doi:&amp;issn=1234-1010&amp;isbn=&amp;volume=22&amp;issue=&amp;spage=1646&amp;pages=1646-53&amp;date=2016&amp;title=Medical+Science+Monitor&amp;atitle=Efficacy+of+Cognitive-Behavioral+Therapy+in+Pediatric+Obsessive-Compulsive+Disorder%3A+A+Meta-Analysis.&amp;aulast=Wu&amp;pid=%3Cauthor%3EWu+Y%3C%2Fauthor%3E%3CAN%3E27182928%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915322/pdf/medscimonit-22-1646.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - Children and/or their parents are in fear and anxiety when admitted to hospitals or undergo invasive surgeries or investigations. Clown therapy has been shown as an effective measure in reducing this hospital fear and anxiety. Hence, we carried out a systematic compilation of the existing evidence on the clinical utility of hospital clowns in pediatric population. 

Electronic databases were searched with an appropriate search strategy, and only randomized controlled trials comparing the effect of clown therapy with standard care in children were included. The key outcome measures were as follows: extent of anxiety and pain felt by children and extent of state and trait parental anxiety. 

Random effect model was applied when moderate to severe heterogeneity was observed. Forest plot, I(2) statistics and risk of bias were evaluated using RevMan 5.3 software. 

A total of 19 studies were found eligible to be included in the systematic review and 16 for meta-analysis. The pooled SMD [95 % CI] for child anxiety score was -0.83 [-1.16, -0.51] favoring clown therapy. Similarly, a statistically significant reduction {SMD [95 % CI] -0.46 [-0.7, -0.21]} in the state anxiety was observed amongst parents.

**CONCLUSION:**
We found that hospital clowns play a significant role in reducing stress and anxiety levels in children admitted to hospitals as well as their parents.

**WHAT IS KNOWN:**
&bull; Trials with clown doctors in pediatric population have shown conflicting results in allaying anxiety amongst children undergoing either hospitalization or invasive procedures What is new: &bull; This is the first systematic review and meta-analysis on hospital clowns &bull; We found out that hospital clowns reduce anxiety amongst children before undergoing either hospitalization or invasive procedures.
AD  - Sridharan, Kannan. Department of Health Sciences, College of Medicine, Nursing and Health Sciences, Fiji National University, Suva, Fiji. skannandr@gmail.com. Sivaramakrishnan, Gowri. Department of Oral Health, College of Medicine, Nursing and Health Sciences, Fiji National University, Suva, Fiji.
AN  - 27605131
AU  - Sridharan,
AU  - K.
AU  - Sivaramakrishnan,
AU  - G.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00431-016-2764-0
DP  - Ovid Technologies
J2  - Eur J Pediatr
L1  - internal-pdf://1154008724/Sridharan-2016-Therapeutic clowns in pediatric.pdf
LA  - English
N1  - Sridharan, Kannan Sivaramakrishnan, Gowri 10.1007/s00431-016-2764-0
PY  - 2016
SP  - 1353-60
T2  - European Journal of Pediatrics
TI  - Therapeutic clowns in pediatrics: a systematic review and meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27605131http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27605131&amp;id=doi:10.1007%2Fs00431-016-2764-0&amp;issn=0340-6199&amp;isbn=&amp;volume=175&amp;issue=10&amp;spage=1353&amp;pages=1353-60&amp;date=2016&amp;title=European+Journal+of+Pediatrics&amp;atitle=Therapeutic+clowns+in+pediatrics%3A+a+systematic+review+and+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Sridharan&amp;pid=%3Cauthor%3ESridharan+K%3C%2Fauthor%3E%3CAN%3E27605131%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://link.springer.com/article/10.1007%2Fs00431-016-2764-0
UR  - http://download.springer.com/static/pdf/93/art%253A10.1007%252Fs00431-016-2764-0.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00431-016-2764-0&amp;token2=exp=1489074503~acl=%2Fstatic%2Fpdf%2F93%2Fart%25253A10.1007%25252Fs00431-016-2764-0.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00431-016-2764-0*~hmac=9f3e7241e6e5988905bbd17d1053a6bee886e149082102f1a608fb3db4a6de17
VL  - 175
ER  -
TY  - JOUR
AB  - **Innledning** 
Barn og unge som opplever samlivsbrudd har generelt sett en økt risiko for emosjonelle og atferdsmessige tilpasningsproblemer. Den gjennomsnittlige forskjellen i risiko for disse barna og barn fra intakte familier er ikke stor, men det kan være store individuelle forskjeller. For å hjelpe og støtte barn og unge i samlivsbrudd gjennom en emosjonell krise og å tilpasse seg alle de praktiske konsekvensene som følger av samlivs‐ brudd, er det utviklet forebyggende programmer i form av gruppetiltak for de som ønsker å delta. Vårt formål i denne systematiske oversikten var å oppsummere effekter av gruppetiltak for barn og unge som opplever eller har opplevd samlivsbrudd i familien. Vi undersøkte effekter på psykososiale utfall, inkludert atferdsmessige utfall, og fysiologiske utfall. 

**Metode** 
Vi søkte etter primærstudier i relevante databaser. Søket ble avsluttet i oktober 2015. To personer gikk uavhengig av hverandre gjennom referanselisten fra litteratursøket og valgte på bakgrunn av tittel og sammendrag de publikasjonene som virket relevante. Potensielt relevante publikasjoner ble bestilt i fulltekst og vurdert for inklusjon på bak‐ grunn av inklusjonskriteriene. De samme to personene vurderte de inkluderte studiene for risiko for skjevheter i resultatene for hvert utfall ved hjelp av en anerkjent sjekkliste. For å bedømme muligheten for å gjøre meta‐analyser vurderte vi heterogeniteten i materialet ved å se på populasjon, tiltak, utfall og design. Spesielt formatet for presentasjonen av resultatene og studiedesign satte begrensninger. Vi gjorde derfor en deskriptiv analyse med presentasjon av studiene og sammenstilling av dem i tabeller med resultater og kvalitetsvurderinger av dokumentasjonen. Kvaliteten på dokumentasjonen ble vurdert av &eacute;n person ved hjelp av GRADE og deretter kontrollert av en annen. 

**Resultat** 
Vi inkluderte 21 studier: 10 randomiserte kontrollerte forsøk og 11 observasjonsstudier. Flesteparten av studiene stammet fra USA og ble utført på 80‐ og 90‐tallet. Risikoen for skjevheter i resultatene vurderte vi stort sett som uklar i de randomiserte studiene og som høy i observasjonsstudiene. Gjennomgående fellestrekk ved tiltakene var at de var kortvarige, mellom 6 og 16 uker, besto av regelmessige møter og benyttet hovedsakelig psykoedukative metoder med vekt på undervisning, støtte og bruk av øvelser i problemløsning som trening på mestring. Alle studiene sammenlignet tiltaket med intet tiltak. Alle studiene inkluderte barn i grunnskole‐/ungdomsskole‐alder, to studier inkluderte også barnehagebarn. Gruppeledere kunne være skolerådgivere, psykologer eller sosionomer. Mange utfall ble målt, ofte med forskjellige verktøy. Vi måtte derfor gjøre et utvalg og valgte da utfall som tilfredsstilte våre inklusjonskriterier og som fortrinnsvis var målt i to eller flere studier. Ni studier målte hvordan barna oppfattet eget selvbilde etter tiltaket, fire målte barnas oppfatninger om foreldrenes samlivsbrudd, seks målte angstsymptomer og fem målte depresjonssymptomer, tre studier målte tilpasning til samlivsbrudd‐situasjonen og fire studier målte holdninger til samlivsbruddet. Foreldre rapporterte hvordan de opplevde barnets sosiale relasjoner, følelser og problemløsningsferdigheter (fire studier), grad av atferdsproblemer og emosjonell fungering (fire studier). Lærere rapporterte hvordan de bedømte elevenes kompetanse (seks studier) og problematferd (åtte studier). To studier rapporterte skolefravær og faglige karakterer. Resultatene for de fleste utfallene var varierende og inkonsistente på tvers av studiene. Dokumentasjonen støtter imidlertid at barn som mottar gruppetiltaket kan oppleve færre angstsymptomer og bedre tilpasning til forhold knyttet til samlivsbruddet. Det er dessuten mulig at foreldrene kan vurdere barnas sosiale atferd, problemløsningsferdig‐ heter og grad av negative følelser som forbedret og at lærere vil kunne vurdere barnas fungering i skolesammenheng på noen områder som forbedret. 

**Diskusjon**
Dokumentasjonen er preget av studier med få deltagere, uklar eller høy risiko for systematiske skjevheter i resultatene, og varierende funn studiene imellom. Etter en helhetlig vurdering fant vi at vi kunne trekke konklusjoner bare for noen utfall. Når resultatene er inkonsistente og dokumentasjonen vurderes som av lav eller svært lav kvalitet, blir det vanskelig å si noe sikkert. Det er da bare videre forskning som kan gi sikrere svar. 

**Konklusjon** 
Barn i samlivsbrudd som deltar i forebyggende gruppetiltak sammenlignet med intet tiltak opplever muligens færre angstsymptomer og en forbedret tilpasning til situasjonen rundt samlivsbruddet. Det er imidlertid usikkert om gruppetiltak påvirker barns selvbilde, depresjonssymptomer eller om det endrer oppfatninger og holdninger til samlivsbruddet. Gruppetiltak kan muligens føre til at foreldrene oppfatter barnas sosiale atferd, problemløsningsferdigheter og hvilke følelser de har i forbindelse med samlivsbruddet som forbedret. Det er imidlertid usikkert om foreldre oppfatter barnas grad av atferdsproblemer og emosjonell fungering som forbedret. Lærere kan muligens synes at barna fungerer bedre på noen områder i skolesammenheng. Det er derimot usikkert om gruppetiltak fører til at lærere oppfatter barnas grad av problematferd, skolefravær og faglige prestasjoner som forbedret.
AU  - Forsetlund,
AU  - L.
AU  - Vist,
AU  - G.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/rapport-2016_gruppetiltak-for-barn-ved-samlivsbrudd.pdf
PY  - 2016
T2  - Folkehelseinstituttet
TI  - Effekter av gruppetiltak for barn og unge som opplever samlivsbrudd
ER  -
TY  - JOUR
AB  - **Background: **
A core social-communication deficit in children with autism spectrum disorder (ASD) is limited joint attention behaviours-important in the diagnosis of ASD and shown to be a powerful predictor of later language ability. Various interventions have been used to train joint attention skills in children with ASD. However, it is unclear which participant, intervention and interventionist factors yield more positive results. 

**Aims: **
The purpose of this systematic review and meta-analysis was to provide a quantitative assessment of the effectiveness of joint attention interventions aimed at improving joint attention abilities in children with ASD. 

**Methods &amp; Procedures: **
The researchers searched six databases for studies meeting the inclusion criteria at two levels: title/abstract and full-text stages. Two independent coders completed data extraction using a coding manual and form developed specifically for this research study. Meta-analysis procedures were used to determine the overall effects of several comparisons including treatment type, treatment administrator, intervention characteristics and follow-up. 

**Main Contribution: **
Fifteen randomized experimental studies met inclusion criteria. All comparisons resulted in statistically significant effects, though overlapping confidence intervals suggest that none of the comparisons were statistically different from each other. Specifically, treatment administrator, dosage and design (control or comparison, etc.) characteristics of the studies do not appear to produce significantly different effects. 

**Conclusions &amp; Implications: **
The results of this meta-analysis provide strong support for explicit joint attention interventions for young children with ASD; however, it remains unclear which children with ASD respond to which type of intervention. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Murza, Kimberly A.: Kimberly.Murza@unco.edu Murza, Kimberly A.: University of Northern Colorado, Campus Box 140, Gunter Hall 1510, Greeley, CO, US, 80639, Kimberly.Murza@unco.edu Murza, Kimberly A.: University of Northern Colorado, Greeley, CO, US Schwartz, Jamie B.: University of Central Florida, Orlando, FL, US Hahs-Vaughn, Debbie L.: University of Central Florida, Orlando, FL, US Nye, Chad: University of Central Florida, Center for Autism and Related Disabilities, Orlando, FL, US
AN  - 2016-12034-001
AU  - Murza,
AU  - K.
AU  - A.
AU  - Schwartz,
AU  - J.
AU  - B.
AU  - Hahs-Vaughn,
AU  - D.
AU  - L.
AU  - Nye,
AU  - C.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/1460-6984.12212
DP  - Ovid Technologies
KW  - autism spectrum disorder, joint attention, intervention, systematic review, meta-analysis
KW  - *Attention
KW  - *Autism Spectrum Disorders
KW  - *Intervention
KW  - Diagnosis
KW  - Meta Analysis
KW  - Developmental Disorders &amp; Autism [3250]
KW  - Human Male Female Childhood (birth-12 yrs)
L1  - internal-pdf://0780832600/Murza-2016-Joint attention interventions for c.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2016
SP  - 236-251
T2  - International Journal of Language and Communication Disorders
TI  - Joint attention interventions for children with autism spectrum disorder: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-12034-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1111%2F1460-6984.12212&amp;issn=1368-2822&amp;isbn=&amp;volume=51&amp;issue=3&amp;spage=236&amp;pages=236-251&amp;date=2016&amp;title=International+Journal+of+Language+%26+Communication+Disorders&amp;atitle=Joint+attention+interventions+for+children+with+autism+spectrum+disorder%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Murza&amp;pid=%3Cauthor%3EMurza%2C+Kimberly+A%3C%2Fauthor%3E%3CAN%3E2016-12034-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1111/1460-6984.12212/asset/jlcd12212.pdf?v=1&amp;t=j0as785o&amp;s=253f3c1fba9db63b0569750d86e0fb8ab9ba200c
VL  - 51
ER  -
TY  - JOUR
AB  - A systematic review with meta-analysis was carried out to investigate the effects of increased nutritional intake, via either macronutrient or multinutrient intervention, during the neonatal period on neurodevelopmental outcomes in infants born at &lt;32 weeks of gestation or weighing &lt;1501 g at birth. 

Although the relationship remains unclear, increased early nutrition may reduce neurodevelopmental impairment in this group of infants. Future research should focus on using standardised nutritional interventions and an agreed neurodevelopmental assessment battery. 

Copyright &copy;2016 Foundation Acta Paediatrica. Published by John Wiley &amp; Sons Ltd.
AN  - 26813585
AU  - Chan,
AU  - S.
AU  - H.
AU  - Johnson,
AU  - M.
AU  - J.
AU  - Leaf,
AU  - A.
AU  - A.
AU  - Vollmer,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/apa.13344
L1  - internal-pdf://1182559404/Chan-2016-Nutrition and neurodevelopmental out.pdf
PY  - 2016
SP  - 587-99
TI  - Nutrition and neurodevelopmental outcomes in preterm infants: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26813585
VL  - 105
ER  -
TY  - JOUR
AB  - Behaviorally based interventions have been demonstrated to be effective to teach social interaction skills for children with autism spectrum disorders in general education. 

However, the overall and moderating effects of these interventions have not been previously investigated in inclusive settings. 

The goal of this study was to investigate the overall effectiveness and contextual factors that moderate intervention effectiveness in inclusive settings. 

Findings showed overall high effect size based on studies previously considered of methodological quality in single-case research. Interventions are demonstrated to be highly effective for children aged 2-10 years. 

While differences were found according to target social skills and behavioral components used, no differential effects were found regarding intervention implementer and peer training. 

The findings highlight the practical significance of behavioral interventions and guide educators toward more suitable evidence-based practices in inclusive settings. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Hoher Camargo, Siglia Pimentel: sigliahoher@yahoo.com.br Hoher Camargo, Siglia Pimentel: Faculdade de Educacao, Universidade Federal de Pelotas, Rua Alberto Rosa, 154, Porto, Pelotas, Brazil, CEP 96010-770, sigliahoher@yahoo.com.br Hoher Camargo, Siglia Pimentel: Faculdade de Educacao, Universidade Federal de Pelotas, Pelotas, Brazil Rispoli, Mandy: College of Education, Purdue University, West Lafayette, IN, US Ganz, Jennifer: Department of Educational Psychology, Texas A&amp;M University, College Station, TX, US Hong, Ee Rea: Department of Human Sciences, University of Tsukuba, Ibaraki, Japan Davis, Heather: Department of Educational Psychology, Texas A&amp;M University, College Station, TX, US Mason, Rose: Juniper Garden Children&#039;s Project, University of Kansas, Kansas City, KS, US
AN  - 2015-48143-001
AU  - Camargo,
AU  - S.
AU  - P.
AU  - H.
AU  - Rispoli,
AU  - M.
AU  - Ganz,
AU  - J.
AU  - Hong,
AU  - E.
AU  - R.
AU  - Davis,
AU  - H.
AU  - Mason,
AU  - R.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10864-015-9240-1
DP  - Ovid Technologies
KW  - Social skills interventions, Meta-analysis, Single-case research, ASD, Inclusive education
KW  - *Autism Spectrum Disorders
KW  - *Intervention
KW  - *Social Skills
KW  - Social Interaction
KW  - Developmental Disorders &amp; Autism [3250]
KW  - Human Childhood (birth-12 yrs) Preschool Age (2-5 yrs) School Age (6-12 yrs)
L1  - internal-pdf://4005169222/Hoher-2016-Behaviorally based interventions fo.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 223-248
T2  - Journal of Behavioral Education
TI  - Behaviorally based interventions for teaching social interaction skills to children with ASD in inclusive settings: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2015-48143-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10864-015-9240-1&amp;issn=1053-0819&amp;isbn=&amp;volume=25&amp;issue=2&amp;spage=223&amp;pages=223-248&amp;date=2016&amp;title=Journal+of+Behavioral+Education&amp;atitle=Behaviorally+based+interventions+for+teaching+social+interaction+skills+to+children+with+ASD+in+inclusive+settings%3A+A+meta-analysis.&amp;aulast=Hoher+Camargo&amp;pid=%3Cauthor%3EHoher+Camargo%2C+Siglia+Pimentel%3C%2Fauthor%3E%3CAN%3E2015-48143-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s10864-015-9240-1
UR  - http://download.springer.com/static/pdf/28/art%253A10.1007%252Fs10864-015-9240-1.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10864-015-9240-1&amp;token2=exp=1489074015~acl=%2Fstatic%2Fpdf%2F28%2Fart%25253A10.1007%25252Fs10864-015-9240-1.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10864-015-9240-1*~hmac=d4d00b6ac38466b238cb10144e39fdcb8aa38d64bf6c0c2f2296841af83cc023
VL  - 25
ER  -
TY  - JOUR
AB  - Several meta-analyses indicate that cognitive-behavioral therapy (CBT) via electronic/technological devices or applications (i.e., eCBT) is an effective alternative to standard therapist-delivered CBT for anxious adults. 

However, we know little about the efficacy of eCBT interventions for anxious children and adolescents. The present meta-analysis set out to investigate the efficacy of eCBT in comparison to standard CBT or waitlist control for anxious children and adolescents. 

Eight randomized controlled studies (N = 404 participants) that targeted anxiety at post-intervention and follow-up were included in the analysis. The results indicated that eCBT was as effective as standard CBT (g = .295) and more effective than waitlist (g = 1.410) in reducing anxiety symptoms. 

Moderation analyses revealed that anxious children and adolescents benefited the most from eCBT in the minimal therapist involvement condition (g = 2.682) in contrast to the significant therapist involvement group (g = .326). 

Furthermore, older participants seemed to extract greater clinical benefits from eCBT in contrast to younger participants (slope = .514). Current eCBT interventions for anxious children and adolescents appear to be promising, but require further investigation. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Podina, Ioana R.: ioana.r.podina@gmail.com; Dobrean, Anca: AncaDobrean@psychology.ro Dobrean, Anca: Department of Clinical Psychology and Psychotherapy, Babes-Bolyai University, No. 37, Republicii St., Cluj-Napoca, Romania, 400015, AncaDobrean@psychology.ro Podina, Ioana R.: Department of Clinical Psychology and Psychotherapy, Babes-Bolyai University, Cluj-Napoca, Romania Mogoase, Cristina: Department of Clinical Psychology and Psychotherapy, Babes-Bolyai University, Cluj-Napoca, Romania David, Daniel: Department of Clinical Psychology and Psychotherapy, Babes-Bolyai University, Cluj-Napoca, Romania Szentagotai, Aurora: Department of Clinical Psychology and Psychotherapy, Babes-Bolyai University, Cluj-Napoca, Romania Dobrean, Anca: Department of Clinical Psychology and Psychotherapy, Babes-Bolyai University, Cluj-Napoca, Romania
AN  - 2015-52848-001
AU  - Podina,
AU  - I.
AU  - R.
AU  - Mogoase,
AU  - C.
AU  - David,
AU  - D.
AU  - Szentagotai,
AU  - A.
AU  - Dobrean,
AU  - A.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10942-015-0228-5
DP  - Ovid Technologies
KW  - Anxiety, Children, Adolescents, Technology, CBT, Meta-analysis
KW  - *Anxiety
KW  - *Cognitive Behavior Therapy
KW  - *Technology
KW  - Adolescent Development
KW  - Childhood Development
KW  - Cognitive Therapy [3311]
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://3930104466/out(1).pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 31-50
T2  - Journal of Rational-Emotive and Cognitive-Behavior Therapy
TI  - A meta-analysis on the efficacy of technology mediated CBT for anxious children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2015-52848-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10942-015-0228-5&amp;issn=0894-9085&amp;isbn=&amp;volume=34&amp;issue=1&amp;spage=31&amp;pages=31-50&amp;date=2016&amp;title=Journal+of+Rational-Emotive+%26+Cognitive-Behavior+Therapy&amp;atitle=A+meta-analysis+on+the+efficacy+of+technology+mediated+CBT+for+anxious+children+and+adolescents.&amp;aulast=Podina&amp;pid=%3Cauthor%3EPodina%2C+Ioana+R%3C%2Fauthor%3E%3CAN%3E2015-52848-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s10942-015-0228-5
VL  - 34
ER  -
TY  - JOUR
AB  - **AIMS: **
To assess the safety of buprenorphine compared with methadone to treat pregnant women with opioid use disorder. 

**METHODS: **
We searched PubMed, Embase and the Cochrane Library from inception to February 2015 for randomized controlled trials (RCT) and observational cohort studies (OBS) that compared buprenorphine with methadone for treating opioid-dependent pregnant women. Two reviewers assessed independently the titles and abstracts of all search results and full texts of potentially eligible studies reporting original data for maternal/fetal/infant death, preterm birth, fetal growth outcomes, fetal/congenital anomalies, fetal/child neurodevelopment and/or maternal adverse events. We ascertained each study&#039;s risk of bias using validated instruments and assessed the strength of evidence for each outcome using established methods. We computed effect sizes using random-effects models for each outcome with two or more studies. 

**RESULTS: **
Three RCTs (n = 223) and 15 cohort OBSs (n = 1923) met inclusion criteria. In meta-analyses using unadjusted data and methadone as comparator, buprenorphine was associated with lower risk of preterm birth [RCT risk ratio (RR)=0.40, 95% confidence interval (CI)=0.18, 0.91; OBS RR=0.67, 95% CI=0.50, 0.90], greater birth weight [RCT weighted mean difference (WMD)=277g, 95% CI=104, 450; OBS WMD=265g, 95% CI=196, 335] and larger head circumference [RCT WMD=0.90cm, 95% CI=0.14, 1.66; OBS WMD=0.68cm, 95% CI=0.41, 0.94]. No treatment differences were observed for spontaneous fetal death, fetal/congenital anomalies and other fetal growth measures, although the power to detect such differences may be inadequate due to small sample sizes. 

**CONCLUSIONS: **
Moderately strong evidence indicates lower risk of preterm birth, greater birth weight and larger head circumference with buprenorphine treatment of maternal opioid use disorder during pregnancy compared with methadone treatment, and no greater harms.
AN  - 27223595
AU  - Zedler,
AU  - B.
AU  - K.
AU  - Mann,
AU  - A.
AU  - L.
AU  - Kim,
AU  - M.
AU  - M.
AU  - Amick,
AU  - H.
AU  - R.
AU  - Joyce,
AU  - A.
AU  - R.
AU  - Murrelle,
AU  - E.
AU  - L.
AU  - Jones,
AU  - H.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/add.13462
L1  - internal-pdf://0197502421/Zedler-2016-Buprenorphine compared with methad.pdf
PY  - 2016
SP  - 2115-2128
T2  - Addiction
TI  - Buprenorphine compared with methadone to treat pregnant women with opioid use disorder: a systematic review and meta-analysis of safety in the mother, fetus and child
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=27223595
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129590/pdf/ADD-111-2115.pdf
VL  - 111
ER  -
TY  - JOUR
AB  - **Background **
Tobacco is the main preventable cause of death and disease worldwide. Adolescent smoking is increasing in many countries with poorer countries following the earlier experiences of affluent countries. Preventing adolescents from starting smoking is crucial to decreasing tobacco-related illness. 

**Objective **
To assess effectiveness of family-based interventions alone and combined with school-based interventions to prevent children and adolescents from initiating tobacco use. 

**Data Sources **
Fourteen bibliographic databases and the Internet, journals hand-searched, and experts consulted. Study Eligibility Criteria, Participants, and Interventions Randomized controlled trials (RCTs) with children or adolescents and families, interventions to prevent starting tobacco use, and follow-up &gt;6 months. 

**Study Appraisal/Synthesis Methods **
Abstracts/titles independently assessed and data independently entered by 2 authors. Risk of bias was assessed with the Cochrane Risk-of-Bias tool. 

**Results **
Twenty-seven RCTs were included. Nine trials of never-smokers compared with a control provided data for meta-analysis. Family intervention trials had significantly fewer students who started smoking. Meta-analysis of 2 RCTs of combined family and school interventions compared with school only, showed additional significant benefit. The common feature of effective high-intensity interventions was encouraging authoritative parenting. 

**Limitations **
Only 14 RCTs provided data for meta-analysis (approximately a third of participants). Of the 13 RCTs that did not provide data for meta-analysis 8 compared a family intervention with no intervention and 1 reported significant effects, and 5 compared a family combined with school intervention with a school intervention only and none reported additional significant effects. 

**Conclusions and Implications of Key **
Findings There is moderate-quality evidence that family-based interventions prevent children and adolescents from starting to smoke. 

Copyright &copy; 2016 Academic Pediatric Association
AD  - (Thomas) Department of Family Medicine, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada (Thomas) Independent Consultant, Calgary, Alberta, Canada (Baker) School of Public Health and Social Work, Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Australia R.E. Thomas, Department of Family Medicine, Faculty of Medicine, University of Calgary, 3330 Hospital Dr NW T2N 4N1, Calgary, Alberta, Canada. E-mail: rthomas@ucalgary.ca
AN  - 612632194
AU  - Thomas,
AU  - R.
AU  - E.
AU  - Baker,
AU  - P.
AU  - R.
AU  - A.
AU  - Thomas,
AU  - B.
AU  - C.
DA  - 01 Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.acap.2015.12.006
DP  - Ovid Technologies
KW  - adolescent
KW  - adolescent behavior
KW  - child
KW  - family
KW  - health promotion
KW  - parent-child relations
KW  - parents
KW  - primary prevention
KW  - tobacco use
KW  - adolescent smoking
KW  - bibliographic database
KW  - child parent relation
KW  - family therapy
KW  - follow up
KW  - human
KW  - Internet
KW  - meta analysis
KW  - randomized controlled trial(topic)
KW  - review
KW  - systematic review
KW  - comparative effectiveness
KW  - controlled study
KW  - family study
KW  - intervention study
KW  - randomized controlled trial
KW  - smoking
KW  - student
KW  - synthesis
L1  - internal-pdf://0845534101/Thomas-2016-Family-Based Interventions in Prev.pdf
LA  - English
M3  - Review
PY  - 2016
SP  - 419-429
T2  - Academic Pediatrics
TI  - Family-Based Interventions in Preventing Children and Adolescents from Using Tobacco: A Systematic Review and Meta-Analysis
UR  - http://www.elsevier.com/wps/find/authored_newsitem.cws_home/companynews05_01099http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=612632194http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.acap.2015.12.006&amp;issn=1876-2859&amp;isbn=&amp;volume=16&amp;issue=5&amp;spage=419&amp;pages=419-429&amp;date=2016&amp;title=Academic+Pediatrics&amp;atitle=Family-Based+Interventions+in+Preventing+Children+and+Adolescents+from+Using+Tobacco%3A+A+Systematic+Review+and+Meta-Analysis&amp;aulast=Thomas&amp;pid=%3Cauthor%3EThomas+R.E.%3C%2Fauthor%3E%3CAN%3E612632194%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S1876285915003794/1-s2.0-S1876285915003794-main.pdf?_tid=e45efdb0-04d0-11e7-93d6-00000aacb362&amp;acdnat=1489068269_7e6b7044739ea088629dbea66c9e7164
VL  - 16
ER  -
TY  - JOUR
AB  - The present meta-analytic review explored long-term treatment effects in children and adolescents, age ranging from 2 to 17 years, treated because of conduct problems. 

The presumed mediators were examined. Various treatments, in all 56 studies including 2589 participants, were included. 32 studies involved an untreated control condition, whereas 24 studies did not. The overall weighted effect size (ES) in conduct problems after termination of treatment was a reduction of ES = 0.08 for a mean follow-up period of 8.9 months. Long-term changes on the presumed mediator showed a small deterioration of ES = -0.06. The moderator analysis confirmed that treatment effects in conduct problems and mediators were related. 

Changes in conduct problems from post-treatment to follow-up were larger in studies with cognitive behavior therapy (CBT) or a combination of behavior therapy (BT) and CBT compared to BT and family therapy. Individual treatments resulted in larger changes in aggressive behaviour as compared to group treatments or a combination of these. 

Treatment effects for both conduct problems and the presumed mediators seem to last, but changes were small. Few studies included teenagers and knowledge of lasting treatment effects is limited for older children including CBT treatments. More knowledge of the mediators involved in treatment is needed, in particular for cognitive and family therapeutic interventions. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Fossum, Sturla: sturla.fossum@uit.no Fossum, Sturla: Regional Centre for Child and Youth Mental Health and Child Welfare - North, Faculty of Health Sciences, UiT The Artic University of Norway, Tromso, Norway, 9016, sturla.fossum@uit.no Fossum, Sturla: Regional Centre for Child and Youth Mental Health and Child Welfare - North, Faculty of Health Sciences, UiT The Artic University of Norway, Tromso, Norway Handegard, Bjorn Helge: Regional Centre for Child and Youth Mental Health and Child Welfare - North, Faculty of Health Sciences, UiT The Artic University of Norway, Tromso, Norway Adolfsen, Frode: Regional Centre for Child and Youth Mental Health and Child Welfare - North, Faculty of Health Sciences, UiT The Artic University of Norway, Tromso, Norway Vis, Svein Arild: Regional Centre for Child and Youth Mental Health and Child Welfare - North, Faculty of Health Sciences, UiT The Artic University of Norway, Tromso, Norway Wynn, Rolf: Department of Clinical Medicine, Faculty of Health Sciences, UiT The Artic University of Norway, Tromso, Norway
AN  - 2015-24274-001
AU  - Fossum,
AU  - S.
AU  - Handegard,
AU  - B.
AU  - H.
AU  - Adolfsen,
AU  - F.
AU  - Vis,
AU  - S.
AU  - A.
AU  - Wynn,
AU  - R.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10826-015-0221-8
DP  - Ovid Technologies
KW  - Long-term, Conduct problems, Mediators, Meta-analysis
KW  - *Conduct Disorder
KW  - *Outpatient Treatment
KW  - *Pediatrics
KW  - Outpatient Services [3371]
KW  - Human Childhood (birth-12 yrs) Preschool Age (2-5 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://1852433850/Fossum-2016-A meta-analysis of long-term outpa.pdf
LA  - English
M3  - Meta Analysis
PY  - 2016
SP  - 15-29
T2  - Journal of Child and Family Studies
TI  - A meta-analysis of long-term outpatient treatment effects for children and adolescents with conduct problems
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-24274-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10826-015-0221-8&amp;issn=1062-1024&amp;isbn=&amp;volume=25&amp;issue=1&amp;spage=15&amp;pages=15-29&amp;date=2016&amp;title=Journal+of+Child+and+Family+Studies&amp;atitle=A+meta-analysis+of+long-term+outpatient+treatment+effects+for+children+and+adolescents+with+conduct+problems.&amp;aulast=Fossum&amp;pid=%3Cauthor%3EFossum%2C+Sturla%3C%2Fauthor%3E%3CAN%3E2015-24274-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s10826-015-0221-8
UR  - http://download.springer.com/static/pdf/377/art%253A10.1007%252Fs10826-015-0221-8.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10826-015-0221-8&amp;token2=exp=1489074231~acl=%2Fstatic%2Fpdf%2F377%2Fart%25253A10.1007%25252Fs10826-015-0221-8.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10826-015-0221-8*~hmac=d193feaf66b839fe6a9be5270752c8cd411e7c74881e2aaf997b5d3f29ce17a2
VL  - 25
ER  -
TY  - JOUR
AB  - **AIM: **
This study aims to provide an overview of the current knowledge available on the effectiveness of pre-operative clown intervention on psychological distress in children and parents. 

**METHODS: **
PubMed, MEDLINE, Embase and PsycINFO databases were searched to identify relevant studies. Systematic review procedures were followed including a quality assessment. Meta-analysis of suitable studies was conducted. 

**RESULTS: **
Eight studies were included; six reported that clown intervention reduced children&#039;s pre-operative anxiety, while one found that children&#039;s pre-operative distress levels were unchanged. Two studies suggested that clown therapy decreased parents&#039; state anxiety, while three others found inconsistent results. No differences were found on parents&#039; trait anxiety score. Meta-analysis of the available data confirmed that clown intervention has a great effect to reduce children&#039;s pre-operative distress (six articles, 341 children, Hedges&#039; g=0.867, 95% confidence intervals: 0.374-1.360, P=0.001), and also had a small-to-medium effect on reducing parents&#039; state anxiety (five articles, 329 parents, Hedges&#039; g=0.338, 95% confidence intervals: 0.112-0.564, P=0.003). 

**CONCLUSIONS: **
While significant variability existed between studies, the meta-analysis confirmed the effectiveness of pre-operative clown therapy on reducing psychological distress in children and parents. Larger randomised controlled trails and cross-cultural studies should be conducted to investigate the effectiveness of clown therapy in greater detail. 

Copyright &copy; 2016 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).
AD  - Zhang, Yongfu. Department of Anaesthesiology, Guangzhou Women and Children&#039;s Medical Centre, Guangzhou, China. yongfuzhang.md@gmail.com. Yang, Yuan. School of Medicine, University of St Andrews, St Andrews, United Kingdom. Lau, Wing Yt. School of Nursing, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China. Garg, Samradhvi. School of Health in Social Science, University of Edinburgh, Edinburgh, United Kingdom. Lao, Jianxin. Department of Anaesthesiology, Guangzhou Women and Children&#039;s Medical Centre, Guangzhou, China.
AN  - 27734555
AU  - Zhang,
AU  - Y.
AU  - Yang,
AU  - Y.
AU  - Lau,
AU  - W.
AU  - Y.
AU  - Garg,
AU  - S.
AU  - Lao,
AU  - J.
DA  - Oct 13
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jpc.13369
DP  - Ovid Technologies
J2  - J Paediatr Child Health
L1  - internal-pdf://2175794172/Zhang_et_al-2017-Journal_of_Paediatrics_and_Ch.pdf
LA  - English
N1  - Zhang, Yongfu Yang, Yuan Lau, Wing Yt Garg, Samradhvi Lao, Jianxin Using Smart Source Parsing Oct
PY  - 2016
SP  - 13
T2  - Journal of Paediatrics and Child Health
TI  - The effectiveness of pre-operative clown intervention on psychological distress: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=27734555http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27734555&amp;id=doi:10.1111%2Fjpc.13369&amp;issn=1034-4810&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2016&amp;title=Journal+of+Paediatrics+%26+Child+Health&amp;atitle=The+effectiveness+of+pre-operative+clown+intervention+on+psychological+distress%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Zhang&amp;pid=%3Cauthor%3EZhang+Y%3C%2Fauthor%3E%3CAN%3E27734555%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 13
ER  -
TY  - JOUR
AB  - **Background:** 
The use of technology in healthcare settings is on the increase and may represent a cost-effective means of delivering rehabilitation. Reductions in treatment time, and delivery in the home, are also thought to be benefits of this approach. Children and adolescents with brain injury often experience deficits in memory and executive functioning that can negatively affect their school work, social lives, and future occupations. Effective interventions that can be delivered at home, without the need for high-cost clinical involvement, could provide a means to address a current lack of provision. We have systematically reviewed studies examining the effects of technology-based interventions for the rehabilitation of deficits in memory and executive functioning in children and adolescents with acquired brain injury.

**Objectives:** 
To assess the effects of technology-based interventions compared to placebo intervention, no treatment, or other types of intervention, on the executive functioning and memory of children and adolescents with acquired brain injury.

**Search methods:** 
We ran the search on the 30 September 2015. We searched the Cochrane Injuries Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Ovid MEDLINE(R), Ovid MEDLINE(R) In-Process &amp; Other Non-Indexed Citations, Ovid MEDLINE(R) Daily and Ovid OLDMEDLINE(R), EMBASE Classic + EMBASE (OvidSP), ISI Web of Science (SCI-EXPANDED, SSCI, CPCI-S, and CPSI-SSH), CINAHL Plus (EBSCO), two other databases, and clinical trials registers. We also searched the internet, screened reference lists, and contacted authors of included studies.

**Selection criteria:** 
Randomised controlled trials comparing the use of a technological aid for the rehabilitation of children and adolescents with memory or executive-functioning deficits with placebo, no treatment, or another intervention.

**Data collection and analysis:** 
Two review authors independently reviewed titles and abstracts identified by the search strategy. Following retrieval of full-text manuscripts, two review authors independently performed data extraction and assessed the risk of bias.

**Main results:** 
Four studies (involving 206 participants) met the inclusion criteria for this review. Three studies, involving 194 participants, assessed the effects of online interventions to target executive functioning (that is monitoring and changing behaviour, problem solving, planning, etc.). These studies, which were all conducted by the same research team, compared online interventions against a &#039;placebo&#039; (participants were given internet resources on brain injury). The interventions were delivered in the family home with additional support or training, or both, from a psychologist or doctoral student. The fourth study investigated the use of a computer program to target memory in addition to components of executive functioning (that is attention, organisation, and problem solving). No information on the study setting was provided, however a speech-language pathologist, teacher, or occupational therapist accompanied participants.Two studies assessed adolescents and young adults with mild to severe traumatic brain injury (TBI), while the remaining two studies assessed children and adolescents with moderate to severe TBI. Risk of biasWe assessed the risk of selection bias as low for three studies and unclear for one study. Allocation bias was high in two studies, unclear in one study, and low in one study. Only one study (n = 120) was able to conceal allocation from participants, therefore overall selection bias was assessed as high.One study took steps to conceal assessors from allocation (low risk of detection bias), while the other three did not do so (high risk of detection bias). Primary outcome 1: Executive functioning: Technology-based intervention versus placeboResults from meta-analysis of three studies (n = 194) comparing online interventions with a placebo for children and adolescents with TBI, favoured the intervention immediately post-treatment (standardised mean difference (SMD) -0.37, 95 onfidence interval (CI) -0.66 to -0.09; P = 0.62; I2 = 0%). (As there is no &#039;gold standard&#039; measure in the field, we have not translated the SMD back to any particular scale.) This result is thought to represent only a small to medium effect size (using Cohen?s rule of thumb, where 0.2 is a small effect, 0.5 a medium one, and 0.8 or above is a large effect); this is unlikely to have a clinically important effect on the participant.The fourth study (n = 12) reported differences between the intervention and control groups on problem solving (an important component of executive functioning). No means or standard deviations were presented for this outcome, therefore an effect size could not be calculated.The quality of evidence for this outcome according to GRADE was very low. This means future research is highly likely to change the estimate of effect. Primary outcome 2: MemoryOne small study (n = 12) reported a statistically significant difference in improvement in sentence recall between the intervention and control group following an eight-week remediation programme. No means or standard deviations were presented for this outcome, therefore an effect size could not be calculated. Secondary outcomesTwo studies (n = 158) reported on anxiety/depression as measured by the Child Behavior Checklist (CBCL) and were included in a meta-analysis. We found no evidence of an effect with the intervention (mean difference -5.59, 95% CI -11.46 to 0.28; I2 = 53%). The GRADE quality of evidence for this outcome was very low, meaning future research is likely to change the estimate of effect.A single study sought to record adverse events and reported none. Two studies reported on use of the intervention (range 0 to 13 and 1 to 24 sessions). One study reported on social functioning/social competence and found no effect. The included studies reported no data for other secondary outcomes (that is quality of life and academic achievement).

**Authors&#039; conclusions:** 
This review provides low-quality evidence for the use of technology-based interventions in the rehabilitation of executive functions and memory for children and adolescents with TBI. As all of the included studies contained relatively small numbers of participants (12 to 120), our findings should be interpreted with caution. The involvement of a clinician or therapist, rather than use of the technology, may have led to the success of these interventions. Future research should seek to replicate these findings with larger samples, in other regions, using ecologically valid outcome measures, and reduced clinician involvement.
AN  - CD011020
AU  - Linden,
AU  - M.
AU  - Hawley,
AU  - C.
AU  - Blackwood,
AU  - B.
AU  - Evans,
AU  - J.
AU  - Anderson,
AU  - V.
AU  - O&#039;Rourke,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd011020.pub2
KW  - Executive Function
KW  - Internet
KW  - Problem Solving
KW  - Software
KW  - Attention
KW  - Brain Injuries [complications] [rehabilitation]
KW  - Memory Disorders [etiology] [rehabilitation]
KW  - Outcome Assessment (Health Care)
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Young Adult[checkword]
L1  - internal-pdf://3947666572/Linden_et_al-2016-The_Cochrane_Library.pdf
PY  - 2016
T2  - Cochrane Database of Systematic Reviews
TI  - Technological aids for the rehabilitation of memory and executive functioning in children and adolescents with acquired brain injury
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD011020.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD011020.pub2/asset/CD011020.pdf?v=1&amp;t=iw7l9ct2&amp;s=91a72787c332d124141ce4272ecea9e8fcf4c454
ER  -
TY  - JOUR
AB  - **Introduction: **
No meta-analysis has evaluated azapirones (serotonin1A receptor partial agonists) as anxiolytics for attention deficit hyperactivity disorder (ADHD). 

**Methods: **
Randomized controlled trials (RCTs) and single-arm trials published before October 27, 2015 were retrieved from major healthcare databases and clinical trial registries. Relative risk and 95% confidence intervals were calculated. 

**Results: **
5 RCTs (n = 429) and 3 single-arm studies (n = 70) were identified. 3 RCTs compared buspirone vs. methylphenidate in children/adolescents, one buspirone patches vs. placebo patches in children/adolescents, and one atomoxetine plus buspirone vs. atomoxetine vs. placebo in adults. The single-arm studies were buspirone trails in children/adolescents. All-cause discontinuation rates and adverse events did not differ between pooled buspirone and methylphenidate groups. No other meta-analyses of buspirone efficacy and safety vs. comparators were conducted due to insufficient data. 2 RCTs found no significant differences in parent and teacher ADHD-Rating Scale total scores between buspirone and methylphenidate, while one reported that methylphenidate improved parent and teacher ADHD-RS total scores vs. buspirone. 

**Discussion: **
It remains unclear whether buspirone use has benefit for ADHD patients and therefore further evidence is needed for better clinical use of buspirone in patients with ADHD. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Kishi, T.: tarok@fujita-hu.ac.jp Kishi, T.: Department of Psychiatry, Fujita Health University School of Medicine, Aichi, Toyoake, Japan, 470-1192, tarok@fujita-hu.ac.jp Matsui, Y.: Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan Matsunaga, S.: Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan Matsuda, Y.: Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan Kishi, T.: Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan Iwata, N.: Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan
AN  - 2016-33300-002
AU  - Matsui,
AU  - Y.
AU  - Matsunaga,
AU  - A.
AU  - Matsuda,
AU  - Y.
AU  - Kishi,
AU  - T.
AU  - Iwata,
AU  - N.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1055/s-0042-102457
DP  - Ovid Technologies
KW  - azapirone, buspirone, attention deficit hyperactivity disorder, systematic review &amp; meta-analysis, guidelines
KW  - *Attention Deficit Disorder with Hyperactivity
KW  - *Drug Therapy
KW  - *Methylphenidate
KW  - Buspirone
KW  - Clinical Psychopharmacology [3340]
KW  - Human
L1  - internal-pdf://3737022566/Matsui-2016-Azapirones for attention deficit h.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2016
SP  - 97-106
T2  - Pharmacopsychiatry
TI  - Azapirones for attention deficit hyperactivity disorder: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-33300-002http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1055%2Fs-0042-102457&amp;issn=0176-3679&amp;isbn=&amp;volume=49&amp;issue=3&amp;spage=97&amp;pages=97-106&amp;date=2016&amp;title=Pharmacopsychiatry&amp;atitle=Azapirones+for+attention+deficit+hyperactivity+disorder%3A+A+systematic+review.&amp;aulast=Matsui&amp;pid=%3Cauthor%3EMatsui%2C+Y%3C%2Fauthor%3E%3CAN%3E2016-33300-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.thieme-connect.com/DOI/DOI?10.1055/s-0042-102457
UR  - https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0042-102457.pdf
VL  - 49
ER  -
TY  - JOUR
AB  - Bakgrunn
Denne artikkelen er en kunnskapsoppsummering om effektene av Depresjonsmestring for ungdom (DU). Artikkelen er en revisjon av en tidligere evaluering av DU i Ungsinn (Kvello, 2013), og omarbeidet i henhold til Ungsinn sine nye kriterier og prosedyrer for vurdering og klassifisering av tiltak (Martinussen m. fl., 2016). DU er et tiltak på 10 sesjoner rettet mot ungdom i alderen 14&ndash;20 år med lett til moderat depresjon eller depresjonssymptomer. I siste versjon av tiltaket er navnet endret til DU &ndash; Mestringskurs for ungdom. Tiltaket er utviklet av Trygve Arne Børve og implementeres i Norge gjennom Fagakademiet og Rådet for psykisk helse. Hensikten med denne artikkelen er å undersøke om DU er virksomt benyttet i vanlig praksis i Norge.

Hovedmålene for DU er å redusere symptomer på lett til moderat depresjon, forebygge utvikling av depresjon og å forebygge tilbakefall. DU følger en fastsatt struktur som er beskrevet i en manual. Gjennom kurset skal deltakerne få en forståelse for sammenhengen mellom tankestil og nedstemthet, kunnskap og ferdigheter til å redusere risikoen for å utvikle depresjon, og å mestre nedstemthet best mulig.

Metode
Kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline, Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS, og SweMed, rapporter fra kunnskapssenteret, NREPP, NICE og Blueprint, samt informasjon gitt fra tiltakseier.

Resultat
Resultatene fra litteratursøket samt en vurdering av kvaliteten på tiltaket presenteres. Forskningsmetodisk kvalitet på foreliggende effektstudie og implementeringskvalitet beskrives, i tillegg til at effektene fra studien summeres opp. DU vurderes som godt beskrevet gjennom en detaljert manual og flere andre dokumenter. Tiltaket har god teoretisk og empirisk forankring gjennom kognitiv atferdsterapi, og det foreligger en norsk pre-post effektivitetsstudie med oppfølgingsmåling 6 måneder etter avsluttet tiltak, samt en norsk kvalitativ evaluering. Effektstudien viser signifikant nedgang i symptomer på depresjon i løpet av intervensjonstiden, med en ytterligere nedgang seks måneder etter avsluttet intervensjon. Effektstørrelsen er sammenlignbar med effektene funnet i referansestudier med kontrollgruppe. Studien har imidlertid metodologiske utfordringer knyttet blant annet til mangel på kontrollgruppe og et stort frafall, noe som gjør resultatene usikre og at effektene trolig er overestimerte. For å sikre implementeringskvalitet er det utarbeidet en sertifiseringsordning, men det er ikke utarbeidet en systematisk evaluering i hvordan tiltaket gjennomføres.

Konklusjon
DU er et godt beskrevet tiltak, med sterk teoretisk forankring rettet mot en av de hyppigste psykiske lidelsene blant ungdom. Det er imidlertid behov for effektstudier med tilfredsstillende kvalitet for å kunne konkludere med at tiltaket gir gode indikasjoner på effekt.

DU klassifiseres på evidensnivå 3: Tiltak med noe dokumentasjon på effekt.
AU  - Wergeland,
AU  - G.,
AU  - J.,
AU  - Skotheim,
AU  - S.,
AU  - Kvello,
AU  - Ø.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2016
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: DU &ndash; Mestringskurs for ungdom (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/kunnskapsoppsummering-og-klassifisering-av-tiltaket-du-depresjonsmestring-for-ungdom-2-utg/
VL  - 2
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
A juvenile curfew has a common sense appeal: keep youth at home during the late night and early morning hours and you will prevent them from committing a crime or being a victim of a crime. This common sense appeal has led to the popularity of curfews, at least within the United States and Iceland. However, prior reviews have questioned the effectiveness of curfews. 

**OBJECTIVES** 
The aim of this review was to synthesize the evidence on the effectiveness of juvenile curfews in reducing criminal behavior and victimization among youth. 

**SEARCH METHODS** 
The systematic search was conducted between January 20, 2014 and March 5, 2014. The search strategy yielded 7,349 titles and abstracts. The initial screening identified 100 of these as potentially relevant and in need of a full text review for study eligibility. Fifteen documents representing 12 unique studies were eligible and coded. 

**SELECTION CRITERIA** 
To be eligible, a study must have tested the effect of an official state or local policy intended to restrict or otherwise penalize a juvenile&#039;s presence outside the home during certain times of day. This must have been a general preventive measure directed at all youth within a certain age range and not a sanction imposed on a specific youth. All quantitative research designs were eligible. An eligible study must have assessed the effect of a curfew on either juvenile criminal behavior or juvenile victimization. The manuscript, published or unpublished, must have been written in English and reported on data collected after 1959. 

**DATA COLLECTION AND ANALYSIS**
The typical evaluation design of an eligible study was a variant on an interrupted time-series. To accommodate these designs, the effect size used in this synthesis was the percent change in the crime or victimization rate during the period of time with a curfew relative to a baseline period, adjusting for any overall linear time trend. The outcomes of interest included crime and victimization, which were categorized by time of day (curfew hours, non-curfew hours, or all hours) and offender or victim age (juvenile or adult). The effects during non-curfew hours and the effects for adults served as control outcomes; that is, outcomes that should be unaffected by a curfew. 

**RESULTS** 
The pattern of evidence suggests that juvenile curfews are ineffective at reducing crime and victimization. The mean effect size for juvenile crime during curfew hours was slightly positive (reflecting a slight increase in crime), whereas it was essentially zero for crime during all hours. Both effects were nonsignificant. Similarly, juvenile victimization also appeared unaffected by the imposition of a curfew ordinance. 

**AUTHORS&rsquo; CONCLUSIONS** 
The evidence suggests that juvenile curfews are ineffective at reducing crime or victimization. This is not, however, a conclusive finding. The observational nature of the research designs creates potential sources of bias, and as such the findings need additional replication. However, many of the most plausible biases should have increased the likelihood of finding an effect. In particular, most of the studies reviewed were conducted during a time period when crime was decreasing throughout the United States. Thus, it appears that juvenile curfews either have no effect on crime and victimization or the effect is too small to be reliability detected with available data.
AU  - Wilson,
AU  - D.
AU  - Gill,
AU  - C.
AU  - Olaghere,
AU  - A.
AU  - McClure,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2016.3
KW  - Youth
KW  - Adolescents
KW  - Crime prevention
KW  - Juvenile delinquency
L1  - internal-pdf://3571013541/Wilson_Review_Curfew_1.pdf
PY  - 2016
T2  - Campbell Systematic Reviews
TI  - Juvenile Curfew Effects on Criminal Behavior and Victimization: A Systematic Review
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The rationale for undertaking this review was to investigate a potential strategy to address the rising prevalence of child and adolescent mental health disorders. The central tenants of mindful parenting appear to be emotional awareness, emotional regulation, attention regulation, intentionality and non-judgmental acceptance. 

**OBJECTIVES: **
The primary objective of this review was to systematically evaluate the effectiveness of mindful parenting programs in promoting children&#039;s, adolescents&#039; and parents&#039; wellbeing, particularly in relation to the intensity of symptoms associated with internalizing (depression, anxiety, stress) and externalizing (conduct) disorders. The secondary objective was to evaluate how effective mindful parenting programs are in improving emotional regulation, attention regulation, quality of the parent-child relationship, resilience and mindfulness of the children, adolescents and parents.

**INCLUSION CRITERIA TYPES OF PARTICIPANTS: **
Children aged between 0 and 18 years and their parents who have completed a mindful parenting program were the focus of this review. 

**TYPES OF INTERVENTION(S)/PHENOMENA OF INTEREST: **
Mindful parenting programs included in this review had a minimum duration of one to two hours per week for 6 to 8 weeks, delivered in a group format, by a facilitator with appropriate training. It included parenting programs that drew upon mindfulness-based stress reduction, mindfulness-based cognitive therapy, mindfulness-based cognitive behavior therapy, dialectical behavior therapy or acceptance commitment therapy. The comparator was the control or waitlist conditions. 

**TYPES OF STUDIES: **
This review focused on randomized controlled trials evaluating the effectiveness of mindful parenting programs. 

**OUTCOMES: **
Primary outcomes were wellbeing or intensity of symptoms associated with internalizing disorders (depression, anxiety, stress) and externalizing disorders (conduct disorders) in children, adolescents and parents. Secondary outcomes were emotional regulation, quality of the parent-child relationship, resilience and mindfulness of the children, adolescents and parents. 

**SEARCH STRATEGY: **
Eight databases were searched for studies evaluating mindful parenting programs from 1997 to November 2014. A three-step search strategy was utilized to retrieve both published and unpublished studies written in English from PubMed, PsycINFO, EMBASE, Scopus, Psychological and Behavioral Sciences Collection, CINAHL, Cochrane Library and ProQuest Dissertations and Theses databases. A logic grid was developed for each of the eight databases to identify the indexing terms and synonyms for the keywords &quot;mindful&quot; and &quot;parenting&quot;. 

**METHODOLOGICAL QUALITY: **
Methodological limitations included small sample sizes leading to lack of statistical power, multiple testing leading to increased alpha errors in addition to information bias caused by a lack of blinding in the implementation and assessment phase. 

**DATA EXTRACTION: **
The data extraction process entailed using the standardized data extraction form from Joanna Briggs Institute Meta-analysis of Statistics Assessment and Review Instrument to extract data from the selected studies. 

**DATA SYNTHESIS: **
The heterogeneity of the samples, the measurement tools and outcomes measured precluded data synthesis through meta-analysis. Conclusions on intervention effects were based on comparisons of the overall statistical significance of the outcomes data. 

**RESULTS: **
The search yielded 1232 articles, from which seven randomized controlled trials met the inclusion criteria. The findings indicate mindful parenting programs may reduce parental stress, increase parents&#039; emotional awareness of their 10-14-year-old children and reduce preschool children&#039;s symptoms associated with externalizing disorders. A recurring finding was that the mindful parenting programs reduced parents&#039; emotional dismissal of their adolescents and preschoolers. 

**CONCLUSIONS: **
At present, there is insufficient evidence to conclude that mindful parenting programs can improve parents&#039; and children&#039;s wellbeing because of the methodological quality of the few studies that met the inclusion criteria. 

**IMPLICATIONS FOR PRACTICE: **
Although there is currently insufficient evidence, mindful parenting programs are increasingly used in a variety of contexts. It may not be appropriate for psychotic or severely traumatized individuals.

**IMPLICATIONS FOR RESEARCH: **
Future studies could make a significant contribution to the field by designing studies with sufficient sample sizes, adequate statistical power as well as blinding participants, facilitators and assessors.
AD  - Townshend, Kishani. 1Joanna Briggs Institute, Faculty of Health Sciences, University of Adelaide, Adelaide, Australia 2Cairns Institute, Faculty of Arts, Education and Social Sciences, James Cook University, Cairns, Australia.
AN  - 27532143
AU  - Townshend,
AU  - K.
AU  - Jordan,
AU  - Z.
AU  - Stephenson,
AU  - M.
AU  - Tsey,
AU  - K.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.11124/JBISRIR-2016-2314
DP  - Ovid Technologies
J2  - JBI Database System Rev Implement Rep
L1  - internal-pdf://0899667430/Townshend-2016-The effectiveness of mindful pa.pdf
LA  - English
N1  - Townshend, Kishani Jordan, Zoe Stephenson, Matthew Tsey, Komla 01938924-201603000-00012
PY  - 2016
SP  - 139-80
T2  - JBI Database Of Systematic Reviews And Implementation Reports
TI  - The effectiveness of mindful parenting programs in promoting parents&#039; and children&#039;s wellbeing: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27532143http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27532143&amp;id=doi:10.11124%2FJBISRIR-2016-2314&amp;issn=2202-4433&amp;isbn=&amp;volume=14&amp;issue=3&amp;spage=139&amp;pages=139-80&amp;date=2016&amp;title=JBI+Database+Of+Systematic+Reviews+And+Implementation+Reports&amp;atitle=The+effectiveness+of+mindful+parenting+programs+in+promoting+parents%27+and+children%27s+wellbeing%3A+a+systematic+review.&amp;aulast=Townshend&amp;pid=%3Cauthor%3ETownshend+K%3C%2Fauthor%3E%3CAN%3E27532143%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 14
ER  -
TY  - JOUR
AB  - **Context: **
Utilization of primary care settings offers a promising approach to enhance parenting practices that are critical for promoting early childhood development. Determining the impact of existing primary care interventions on key parenting behaviors will aid providers and policy makers as they seek strategies to improve early child outcomes. 

**Objective: **
To evaluate the efficacy of primary care-based interventions on parenting practices that promote early child development among children younger than 36 months. Data Sources: PubMed, Excerpta Medica dataBASE, PsycINFO, and Cumulative Index to Nursing and Allied Health Literature databases were searched electronically. 

**Study Selection: **
English-language articles that were quasi-randomized or randomized controlled trials, included parents of children &lt;36 months of age, and reported outcomes related to parenting behaviors that promote early child development. 

**Data Extraction: **
Two reviewers independently extracted data regarding participants, interventions, and outcomes. Quantitative meta-analyses were conducted with random effects for study and fitted with restricted maximum likelihood methods. 

**Results: **
The review included 13 studies reporting parenting outcomes in 2 categories: participation in cognitively stimulating activities and positive parent-child interactions. We found a statistically significant positive effect of primary care-delivered interventions and parent-child interactions (summary standardized mean difference 0.29, 95% confidence interval [CI] 0.06-0.52, P &lt; .0001) and participation in cognitively stimulating activities (summary standardized mean difference 0.34, 95% CI 0.03-0.54; summary odds ratio 0.13, 95% CI 0.01-0.25, P &lt; .0001). 

**Limitations:**
Limitations included heterogeneity in measures used, outcomes, and timing of assessments. 

**Conclusions: **
Primary care-based interventions modestly affect positive parenting behaviors important for early childhood development. Randomized controlled trials with comparable outcome measures using standardized assessments are needed to assess further beneficial impacts. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2016-23914-013
AU  - Shah,
AU  - R.
AU  - Kennedy,
AU  - S.
AU  - Clark,
AU  - M.
AU  - D.
AU  - Bauer,
AU  - S.
AU  - C.
AU  - Schwartz,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
L1  - internal-pdf://2644785298/Shah-2016-Primary care-based interventions to.pdf
PY  - 2016
SP  - 1-14
TI  - Primary care-based interventions to promote positive parenting behaviors: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2016-23914-013
VL  - 137
ER  -
TY  - JOUR
AB  - Evidence suggests that omega-3 fatty acids are important for a variety of mental health outcomes and have been shown to improve both mood and behaviors. 

However, there is little consensus on whether omega-3 fatty acids are beneficial for reducing aggressive behaviors. The current study assesses the relationship between omega-3 fatty acids and aggression. A total of 73 effect sizes were calculated among 40 studies involving 7173 participants from both intervention and observational research designs. 

Effect sizes were separately meta-analyzed for two-group comparison studies (SMD = 0.20), pre-post contrast studies (ES&lt;inf&gt;sg&lt;/inf&gt; = 0.62), and associational studies (r = -0.06), in the fixed-effect model. Results from the random-effects model also suggest a range of effects of omega-3 fatty acids on reducing aggression (SMD = 0.24; ES&lt;inf&gt;sg&lt;/inf&gt; = 0.82; r = -0.09). 

Patterns in the relationship between omega-3s and aggression were additionally observed. Moderator analyses indicated that the effect of omega-3s on aggression is conditioned by how aggressive behaviors are measured, such as through self-report or parent/teacher surveys. 

Copyright &copy; 2016 Elsevier Ltd
AD  - (Gajos, Beaver) College of Criminology and Criminal Justice, Florida State University, Tallahassee, FL 32306-1273, United States (Beaver) Center for Social and Humanities Research, King Abdulaziz University, Jeddah, Saudi Arabia J.M. Gajos, College of Criminology and Criminal Justice, Florida State University, Tallahassee, FL 32306-1273, United States. E-mail: jmg09m@my.fsu.edu
AN  - 611587712
AU  - Gajos,
AU  - J.
AU  - M.
AU  - Beaver,
AU  - K.
AU  - M.
DA  - 01 Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.neubiorev.2016.07.017
DP  - Ovid Technologies
KW  - Aggression
KW  - Meta-analysis
KW  - Omega-3 fatty acids
KW  - adolescent
KW  - adult
KW  - controlled study
KW  - diet supplementation
KW  - dietary intake
KW  - effect size
KW  - female
KW  - human
KW  - male
KW  - nerve cell differentiation
KW  - observational study
KW  - priority journal
KW  - review
KW  - self report
KW  - docosahexaenoic acid
KW  - essential fatty acid
KW  - icosapentaenoic acid
KW  - disease model
KW  - meta analysis
KW  - participant observation
KW  - teacher
KW  - omega 3 fatty acid
L1  - internal-pdf://0518056151/Gajos-2016-The effect of omega-3 fatty acids o.pdf
LA  - English
M3  - Review
PY  - 2016
SP  - 147-158
T2  - Neuroscience and Biobehavioral Reviews
TI  - The effect of omega-3 fatty acids on aggression: A meta-analysis
UR  - http://www.elsevier.com/locate/neubiorevhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=611587712http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.neubiorev.2016.07.017&amp;issn=0149-7634&amp;isbn=&amp;volume=69&amp;issue=&amp;spage=147&amp;pages=147-158&amp;date=2016&amp;title=Neuroscience+and+Biobehavioral+Reviews&amp;atitle=The+effect+of+omega-3+fatty+acids+on+aggression%3A+A+meta-analysis&amp;aulast=Gajos&amp;pid=%3Cauthor%3EGajos+J.M.%3C%2Fauthor%3E%3CAN%3E611587712%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0149763416300203/1-s2.0-S0149763416300203-main.pdf?_tid=dfe8e994-04c6-11e7-87b5-00000aacb35e&amp;acdnat=1489063966_5e040de422488f2e5646b36f3900d974
VL  - 69
ER  -
TY  - JOUR
AB  - To conduct a meta-analysis summarizing the effectiveness of school-based brief alcohol interventions (BAIs) among adolescents and to examine possible iatrogenic effects due to deviancy training in group-delivered interventions, a systematic search for eligible studies was undertaken, current through December 31, 2012. Studies were eligible for inclusion if they used an experimental/quasi-experimental design; focused on school-based BAIs; enrolled adolescent participants; and reported an alcohol-related outcome measure. 

Studies were coded for key variables, and outcome effect sizes were analyzed as standardized mean differences adjusted for small samples (Hedges&#039; g). Analyses were conducted using inverse-variance weighted mixed-effects meta-regression models. Sensitivity analyses were also conducted. 

Across all 17 studies eligible for inclusion, school-based BAIs were associated with significant improvements among adolescents, whereby adolescents in the BAI groups reduced their alcohol consumption relative to the control groups (=0.34, 95 % CI [0.11, 0.56]). Subgroup analyses indicated that whereas individually-delivered BAIs were effective (=0.58, 95 % CI [0.23, 0.92]), there was no evidence that group-delivered BAIs were associated with reductions in alcohol use (=-0.02, 95 % CI [-0.17, 0.14]). 

Delivery format was confounded with program modality, however, such that motivational enhancement therapy was the most effective modality, but was rarely implemented in group-delivered interventions. Some school-based BAIs are effective in reducing adolescent alcohol consumption, but may be ineffective if delivered in group settings. 

Future research should explore whether group-delivered BAIs that use motivational enhancement therapy components may yield beneficial outcomes like those observed in individually-delivered programs.
AD  - Hennessy, Emily A. Department of Human &amp; Organizational Development, Peabody College, Vanderbilt University, 220 Appleton Place, Mayborn Building, Nashville, TN, 37203-5721, USA, emily.a.hennessy@vanderbilt.edu.
AN  - 25294110
AU  - Hennessy,
AU  - E.
AU  - A.
AU  - Tanner,-Smith,
AU  - E.
AU  - E.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
J2  - Prev Sci
KW  - Adolescent
KW  - *Alcohol Drinking/pc [Prevention &amp; Control]
KW  - Female
KW  - Humans
KW  - Male
KW  - *School Health Services/og [Organization &amp; Administration]
L1  - internal-pdf://3819568363/Hennessy-2015-Effectiveness of brief school-ba.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural
N1  - Hennessy, Emily A Tanner-Smith, Emily E
PY  - 2015
SP  - 463-74
T2  - Prevention Science
TI  - Effectiveness of brief school-based interventions for adolescents: a meta-analysis of alcohol use prevention programs
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25294110http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25294110&amp;id=doi:10.1007%2Fs11121-014-0512-0&amp;issn=1389-4986&amp;isbn=&amp;volume=16&amp;issue=3&amp;spage=463&amp;pages=463-74&amp;date=2015&amp;title=Prevention+Science&amp;atitle=Effectiveness+of+brief+school-based+interventions+for+adolescents%3A+a+meta-analysis+of+alcohol+use+prevention+programs.&amp;aulast=Hennessy&amp;pid=%3Cauthor%3EHennessy+EA%3C%2Fauthor%3E%3CAN%3E25294110%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636019/pdf/nihms733094.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - **Purpose: **
Effective treatments for juvenile sexual offenders are needed to reduce the societal impact of sexual crimes. The purpose of this paper is to review the empirical literature on treatments for this clinical population. 

**Design/methodology/approach: **
The authors searched PsycINFO and MEDLINE (via PubMed) for studies that evaluated outcomes of treatments with juvenile sexual offenders. 

**Findings:** 
There are a small but growing number of treatment studies (n = 10) with juvenile sexual offenders, and all of these studies evaluated cognitive-behavioral therapy or multisystemic therapy for problem sexual behaviors. The results of these studies are promising, although conclusions about treatment effectiveness have been frequently limited by methodological problems. 

**Originality/value: **
The authors provide recommendations for treatment providers and policymakers to consider in their decisions about interventions for juvenile sexual offenders. Furthermore, the authors offer suggestions for researchers who seek to develop effective interventions targeting this clinical population. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Borduin, Charles M.: borduinc@missouri.edu Borduin, Charles M., borduinc@missouri.edu Dopp, Alex R.: Department of Psychological Sciences, University of Missouri, Columbia, MO, US Borduin, Charles M.: Department of Psychological Sciences, University of Missouri, Columbia, MO, US Brown, Cynthia E.: Department of Psychological Sciences, University of Missouri, Columbia, MO, US
AN  - 2015-44050-002
AU  - Dopp,
AU  - A.
AU  - R.
AU  - Borduin,
AU  - C.
AU  - M.
AU  - Brown,
AU  - C.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1108/jacpr-01-2015-0155
DP  - Ovid Technologies
KW  - Literature review, Cognitive-behavioral therapy, Evidence-based treatment, Family systems therapy, Juvenile sexual offenders, Multisystemic therapy
KW  - *Cognitive Behavior Therapy
KW  - *Evidence Based Practice
KW  - *Juvenile Delinquency
KW  - *Sex Offenses
KW  - *Treatment Outcomes
KW  - Intervention
KW  - Criminal Behavior &amp; Juvenile Delinquency [3236]
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human Adolescence (13-17 yrs)
L1  - internal-pdf://1071565191/Dopp_2015.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2015
SP  - 223-236
T2  - Journal of Aggression, Conflict and Peace Research
TI  - Evidence-based treatments for juvenile sexual offenders: Review and recommendations
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-44050-002http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1108%2FJACPR-01-2015-0155&amp;issn=1759-6599&amp;isbn=&amp;volume=7&amp;issue=4&amp;spage=223&amp;pages=223-236&amp;date=2015&amp;title=Journal+of+Aggression%2C+Conflict+and+Peace+Research&amp;atitle=Evidence-based+treatments+for+juvenile+sexual+offenders%3A+Review+and+recommendations.&amp;aulast=Dopp&amp;pid=%3Cauthor%3EDopp%2C+Alex+R%3C%2Fauthor%3E%3CAN%3E2015-44050-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 7
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Previous meta-analyses of cognitive-behavioural therapy (CBT) for children and young people with anxiety disorders have not considered the efficacy of transdiagnostic CBT for the remission of childhood anxiety. 

**AIM: **
To provide a meta-analysis on the efficacy of transdiagnostic CBT for children and young people with anxiety disorders.

**METHODS: **
The analysis included randomized controlled trials using transdiagnostic CBT for children and young people formally diagnosed with an anxiety disorder. An electronic search was conducted using the following databases: ASSIA, Cochrane Controlled Trials Register, Current Controlled Trials, Medline, PsycArticles, PsychInfo, and Web of Knowledge. The search terms included &quot;anxiety disorder(s)&quot;, &quot;anxi*&quot;, &quot;cognitive behavio*, &quot;CBT&quot;, &quot;child*&quot;, &quot;children&quot;, &quot;paediatric&quot;, &quot;adolescent(s)&quot;, &quot;adolescence&quot;, &quot;youth&quot; and &quot;young pe*&quot;. The studies identified from this search were screened against the inclusion and exclusion criteria, and 20 studies were identified as appropriate for inclusion in the current meta-analysis. Pre- and posttreatment (or control period) data were used for analysis. 

**RESULTS: **
Findings indicated significantly greater odds of anxiety remission from pre- to posttreatment for those engaged in the transdiagnostic CBT intervention compared with those in the control group, with children in the treatment condition 9.15 times more likely to recover from their anxiety diagnosis than children in the control group. Risk of bias was not correlated with study effect sizes. 

**CONCLUSIONS: **
Transdiagnostic CBT seems effective in reducing symptoms of anxiety in children and young people. Further research is required to investigate the efficacy of CBT for children under the age of 6.
AD  - Ewing, Donna L. University of Sussex,Brighton,UK. Monsen, Jeremy J. East London Consortium of Educational Psychologists,London,UK. Thompson, Ellen J. University of Sussex,Brighton,UK. Cartwright-Hatton, Sam. University of Sussex,Brighton,UK. Field, Andy. University of Sussex,Brighton,UK.
AN  - 24331028
AU  - Ewing,
AU  - D.
AU  - L.
AU  - Monsen,
AU  - J.
AU  - J.
AU  - Thompson,
AU  - E.
AU  - J.
AU  - Cartwright-Hatton,
AU  - S.
AU  - Field,
AU  - A.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1017/S1352465813001094.
DP  - Ovid Technologies
J2  - Behav
KW  - Adolescent
KW  - Age Factors
KW  - *Anxiety Disorders/th [Therapy]
KW  - Child
KW  - *Cognitive Therapy/mt [Methods]
KW  - Cognitive Therapy/sn [Statistics &amp; Numerical Data]
KW  - Female
KW  - Humans
KW  - Male
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://2559368573/Ewing-2015-A Meta-Analysis of Transdiagnostic.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Ewing, Donna L Monsen, Jeremy J Thompson, Ellen J Cartwright-Hatton, Sam Field, Andy S1352465813001094
PY  - 2015
SP  - 562-77
T2  - Behavioural and Cognitive Psychotherapy
TI  - A Meta-Analysis of Transdiagnostic Cognitive Behavioural Therapy in the Treatment of Child and Young Person Anxiety Disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24331028http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24331028&amp;id=doi:10.1017%2FS1352465813001094&amp;issn=1352-4658&amp;isbn=&amp;volume=43&amp;issue=5&amp;spage=562&amp;pages=562-77&amp;date=2015&amp;title=Behavioural+%26+Cognitive+Psychotherapy&amp;atitle=A+Meta-Analysis+of+Transdiagnostic+Cognitive+Behavioural+Therapy+in+the+Treatment+of+Child+and+Young+Person+Anxiety+Disorders.&amp;aulast=Ewing&amp;pid=%3Cauthor%3EEwing+DL%3C%2Fauthor%3E%3CAN%3E24331028%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169709/pdf/emss-58660.pdf
VL  - 43
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Mindfulness-based therapies are being used in a wide range of common chronic conditions in both treatment and prevention despite lack of consensus about their effectiveness in different patient categories.

**OBJECTIVE: **
To systematically review the evidence of effectiveness MBSR and MBCT in different patient categories.

**METHODS: **
A systematic review and meta-analysis of systematic reviews of RCTs, using the standardized MBSR or MBCT programs. We used PRISMA guidelines to assess the quality of the included reviews and performed a random effects meta-analysis with main outcome measure Cohen&#039;s d. All types of participants were considered.

**RESULTS: **
The search produced 187 reviews: 23 were included, covering 115 unique RCTs and 8,683 unique individuals with various conditions. Compared to wait list control and compared to treatment as usual, MBSR and MBCT significantly improved depressive symptoms (d=0.37; 95%CI 0.28 to 0.45, based on 5 reviews, N=2814), anxiety (d=0.49; 95%CI 0.37 to 0.61, based on 4 reviews, N=2525), stress (d=0.51; 95%CI 0.36 to 0.67, based on 2 reviews, N=1570), quality of life (d=0.39; 95%CI 0.08 to 0.70, based on 2 reviews, N=511) and physical functioning (d=0.27; 95%CI 0.12 to 0.42, based on 3 reviews, N=1015). Limitations include heterogeneity within patient categories, risk of publication bias and limited long-term follow-up in several studies.

**CONCLUSION:** 
The evidence supports the use of MBSR and MBCT to alleviate symptoms, both mental and physical, in the adjunct treatment of cancer, cardiovascular disease, chronic pain, depression, anxiety disorders and in prevention in healthy adults and children.
AD  - Gotink, Rinske A. Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands; Department of Psychiatry, section Medical Psychology and Psychotherapy, Erasmus MC, Rotterdam, the Netherlands; Department of Radiology, Erasmus MC, Rotterdam, the Netherlands.Chu, Paula. Department of Health Policy, Harvard University, Cambridge, United States of America.Busschbach, Jan J V. Department of Psychiatry, section Medical Psychology and Psychotherapy, Erasmus MC, Rotterdam, the Netherlands.Benson, Herbert. Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States of America; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States of America.Fricchione, Gregory L. Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, United States of America; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States of America.Hunink, M G Myriam. Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands; Department of Radiology, Erasmus MC, Rotterdam, the Netherlands; Department of Health Policy and Management, Harvard School of Public Health, Boston, United States of America.
AN  - 25881019
AU  - Gotink,
AU  - R.
AU  - A.
AU  - Chu,
AU  - P.
AU  - Busschbach,
AU  - J.
AU  - J.
AU  - Benson,
AU  - H.
AU  - Fricchione,
AU  - G.
AU  - L.
AU  - Hunink,
AU  - M.
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0124344
DP  - Ovid Technologies
J2  - PLoS ONE
KW  - Adult
KW  - Child, Preschool
KW  - *Delivery of Health Care/mt [Methods]
KW  - Humans
KW  - *Mindfulness
L1  - internal-pdf://0186974148/Gotink-2015-Standardised mindfulness-based int.pdf
LA  - English
M3  - Meta-Analysis
Research Support, Non-U.S. Gov&#039;t
Review
N1  - Gotink, Rinske AChu, PaulaBusschbach, Jan J VBenson, HerbertFricchione, Gregory LHunink, M G Myriam
PY  - 2015
SP  - e0124344
T2  - PLoS ONE [Electronic Resource]
TI  - Standardised mindfulness-based interventions in healthcare: an overview of systematic reviews and meta-analyses of RCTs
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=25881019
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25881019&amp;id=doi:10.1371%2Fjournal.pone.0124344&amp;issn=1932-6203&amp;isbn=&amp;volume=10&amp;issue=4&amp;spage=e0124344&amp;pages=e0124344&amp;date=2015&amp;title=PLoS+ONE+%5BElectronic+Resource%5D&amp;atitle=Standardised+mindfulness-based+interventions+in+healthcare%3A+an+overview+of+systematic+reviews+and+meta-analyses+of+RCTs.&amp;aulast=Gotink&amp;pid=%3Cauthor%3EGotink+RA%3C%2Fauthor%3E%3CAN%3E25881019%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400080/pdf/pone.0124344.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
Youth drug use is a severe problem worldwide. This review focuses on Cognitive-Behavioural Therapy (CBT) as a treatment for young people who misuse non-opioid drugs, such as cannabis, amphetamines, ecstasy and cocaine, which are strongly associated with a range of health and social problems. CBT is an individualized and multicomponent intervention that combines behavioural and cognitive therapy. While behavioural therapy mainly focuses on external settings and observable behaviour, cognitive therapy is concerned with internal cognitive processes. The primary focus of CBT is to reduce users&rsquo; positive expectations about drug use, to enhance their self-confidence to resist drugs, and to improve their skills for problem-solving and for coping with daily life stressors. 

**OBJECTIVES** 
The objective of this review is to assess the effectiveness of CBT for young people (aged 13-21) in outpatient treatment for non-opioid drug use and to explore any factors that may moderate outcomes. 

**SEARCH STRATEGY**
An extensive search strategy was used to identify qualifying studies. A wide range of electronic bibliographic databases were searched along with government and policy databanks, grey literature databases, citations in other reviews and in the included primary studies, hand searches of relevant journals, and Internet searches using Google. We also corresponded with researchers in the CBT field. No language or date restrictions were applied to the searches. 

**SELECTION CRITERIA** 
Studies were required to meet several criteria to be eligible for inclusion. Studies must: &bull; have involved CBT treatment for young people aged 13-21 years enrolled in outpatient treatment for non-opioid drug use; &bull; have used experimental, quasi-randomised or non-randomised controlled designs; &bull; not have focused exclusively on treating mental disorders; and &bull; have had CBT as the primary intervention. 

**DATA COLLECTION AND ANALYSIS** The literature search yielded a total of 18,514 references, of which 394 were deemed potentially relevant and retrieved for eligibility determination. Of these, 360 did not fulfil the screening criteria and were excluded. Four records were unobtainable. A total of seven unique studies, reported in 17 papers, were included in the review. Meta-analysis was used to examine the effects of CBT on drug use reduction, social and family functioning, school problems, treatment retention and criminal activity compared to a group of other interventions (Adolescent Community Reinforcement Approach (ACRA), Chestnut Bloomington Outpatient (CBOP) (+Assertive Continuing Care (ACC)), Drugs Harm Psychoeducation curriculum (DHPE), Functional Family Therapy (FFT), Interactional Therapy (IT), Multidimensional Family Therapy (MDFT), and Psychoeducational Therapy (PET)). RESULTS Our main objective was to evaluate the current evidence on the effect of CBT on abstinence and drug use reduction for young people in outpatient treatment for non-opioid drug use. Seven randomised trials, involving 953 participants, were included in this review. Each of the seven included studies compared CBT to another intervention. We analysed the effects in the short term (from the start of treatment to up to 6 months thereafter), medium term (from 6 months to less than 12 months after the start of treatment), and long term (12 months or more after the start of treatment). We analysed CBT that was delivered with an add-on component such as motivational interviewing (four studies) separately from CBT that was delivered without an add-on component (three studies). Based on meta-analysis of data from the four included studies analysing CBT with an add-on component, there was no evidence of a relative effect of CBT for the reduction of youth drug use frequency compared to other interventions (ACRA, CBOP (+ACC), DHPE, FFT and MDFT). The random effects standardized mean difference was -0.14 (95% CI -0.64, 0.36) for the short term based on four studies, -0.06 (95% CI -0.44, 0.32) for the medium term based on four studies and -0.15 (95% CI -0.36, 0.06) for the long t rm based on two studies. Based on meta-analysis of data from the four included studies analysing CBT without an add-on component, there was no evidence of a relative effect of CBT for the reduction of youth drug use frequency compared to other interventions (IT, MDFT, and PET ). The random effects standardized mean difference was -0.13 (95% CI -0.68, 0.42) for the short term based on two studies, -0.08 (95% CI -0.48, 0.31) for the medium term based on three studies and 0.02 (95% CI -0.48, 0.52) for the long term based on two studies. Thus, the available data does not support the hypothesis that there is a drug use reduction effect from using CBT with young drug users compared to other interventions (ACRA, CBOP (+ACC), DHPE, FFT, IT, MDFT, and PET ). Statistically significant heterogeneity was present in the short term. In the medium term statistically significant heterogeneity was present between studies analysing CBT with an add-on component. In the analysis of studies without an add-on component there was no statistically significant heterogeneity in the medium term. Due to the low power of detecting heterogeneity with only two studies included in the analysis, this result should be interpreted with caution. There was no heterogeneity between studies in the long term; however, with only two studies included in the analyses the power to detect heterogeneity was low. The primary outcome measured as recovery could only be analysed in the long term. The meta-analysis of CBT with an add-on component was inconclusive as the eight different comparison combinations analysed showed different results. Only one study analysing CBT without an add-on component provided data on recovery status. The reported effect was not statistically significant. Several sensitivity analyses were performed with respect to analysis method, risk of bias, and intervention characteristics. None of the results from these sensitivity analyses changed the overall conclusions. No statistically significant differences between CBT, with or without an add-on component, and the comparison interventions (ACRA, CBOP (+ACC), DHPE, FFT, IT, MDFT, and PET ) were found for the secondary outcomes of psychological problems, family problems, school problems, risk behaviour (related to crime) and retention. No studies reported on other adverse effects, such as suicide or overdoses. 

**AUTHORS&rsquo; CONCLUSIONS**
Based on the seven studies included in this review, there was no evidence that CBT interventions perform better or worse than the comparison interventions (ACRA, CBOP (+ACC), DHPE, FFT, IT, MDFT, and PET ) with respect to reduction in young people&rsquo;s drug use. The evidence drawn from this systematic review is based on seven included studies analysed in two separate analyses, depending on whether the intervention was CBT with an add-on component such as motivational interviewing (four studies) or CBT without an add-on component (three studies). The seven studies are very different in terms of their findings regarding the effects of CBT interventions compared to other interventions (ACRA, CBOP (+ACC), DHPE, FFT, IT, MDFT, and PET ) on young people&rsquo;s drug use. Therefore, the overall conclusion regarding the effect of CBT interventions compared to these other interventions on drug use reduction for young people aged 13 to 21 years should be interpreted with caution. The conclusions that can be drawn would be more convincing if more studies were available.
AU  - Filges,
AU  - T.
AU  - Knudsen,
AU  - A.
AU  - S.
AU  - D.
AU  - Svendsen,
AU  - M.
AU  - M.
AU  - Kowalski,
AU  - K.
AU  - Benjaminsen,
AU  - L.
AU  - Jørgensen,
AU  - A.
AU  - M.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2015.3
PY  - 2015
T2  - Campbell Systematic Reviews
TI  - Cognitive-Behavioural Therapies for Young People in Outpatient Treatment for Non-opioid Drug Use: A Systematic Review
ER  -
TY  - JOUR
AB  - **Objective: **
To examine the overall effect of individual depression prevention programs on future likelihood of depressive disorder and reduction in depressive symptoms. In addition, we have investigated whether Cognitive Behavioural Therapy (CBT), Interpersonal Therapy (IPT) and other therapeutic techniques may modify this effectiveness. 

**Methods: **
This study is based on and includes the trial data from meta-analyses conducted in the Cochrane systematic review of depression prevention programs for children and adolescents by Merry et al. (2011). All trials were published or unpublished English language randomized controlled trials (RCTs) or cluster RCTs of any psychological or educational intervention compared to no intervention to prevent depression in children and adolescents aged 5-19 years. 

**Results: **
There is some evidence that the therapeutic approach used in prevention programs modifies the overall effect. CBT is the most studied type of intervention for depression prevention, and there is some evidence of its effectiveness in reducing the risk of developing a depressive disorder, particularly in targeted populations. Fewer studies employed IPT, however this approach appears promising. To our knowledge, this is the first study to have explored how differences in the approach taken in the prevention programs modify the overall treatment effects of prevention programs for children and adolescents. 

**Conclusions:** 
More research is needed to identify the specific components of CBT that are most effective or indeed if there are other approaches that are more effective in reducing the risk of future depressive episodes. It is imperative that prevention programs are suitable for large scale roll-out, and that emerging popular modes of delivery, such as online dissemination continue to be rigorously tested.
AD  - [Hetrick, Sarah E.; Cox, Georgina R.] Natl Ctr Excellence Youth Mental Hlth, Orygen, Parkville, Vic 3052, Australia. [Merry, Sally N.] Univ Auckland, Werry Ctr Child &amp; Adolescent Mental Hlth, Fac Med &amp; Hlth Sci, Dept Psychol Med,Sch Med, Auckland 1142, New Zealand. Hetrick, SE (reprint author), Natl Ctr Excellence Youth Mental Hlth, Orygen, 35 Poplar Rd, Parkville, Vic 3052, Australia. shetrick@unimelb.edu.au; gcox@unimelb.edu.au; s.merry@auckland.ac.nz
AN  - WOS:000359190300018
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Cox,
AU  - G.
AU  - R.
AU  - Merry,
AU  - S.
AU  - N.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3390/ijerph120504758
J2  - Int. J. Environ. Res. Public Health
KW  - prevention
KW  - depressive disorder
KW  - evidence-based practice
KW  - children
KW  - adolescent
KW  - meta-analysis
KW  - school-based prevention
KW  - randomized controlled-trial
KW  - group cognitive
KW  - intervention
KW  - penn-resiliency-program
KW  - follow-up
KW  - anxiety symptoms
KW  - risk
KW  - adolescents
KW  - universal
KW  - efficacy
KW  - childhood
KW  - Environmental Sciences &amp; Ecology
KW  - Public, Environmental &amp; Occupational
KW  - Health
L1  - internal-pdf://0054919989/Hetrick-2015-Where to Go from Here_ An Explora.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CO5HN Times Cited: 6 Cited Reference Count: 68 Hetrick, Sarah E. Cox, Georgina R. Merry, Sally N. 6 4 22 Mdpi ag Basel
PY  - 2015
SP  - 4758-4795
T2  - International Journal of Environmental Research and Public Health
TI  - Where to Go from Here? An Exploratory Meta-Analysis of the Most Promising Approaches to Depression Prevention Programs for Children and Adolescents
UR  - &lt;Go to ISI&gt;://WOS:000359190300018
UR  - http://www.mdpi.com/1660-4601/12/5/4758/pdf
VL  - 12
ER  -
TY  - JOUR
AB  - One quarter of children and young people (CYP) experience anxiety and/or depression before adulthood, but treatment is sometimes unavailable or inadequate. 

Self-help interventions may have a role in augmenting treatment and this work aimed to systematically review the evidence for computerised anxiety and depression interventions in CYP aged 5-25 years old. 

Databases were searched for randomised controlled trials and 27 studies were identified. For young people (12-25 years) with risk of diagnosed anxiety disorders or depression, computerised CBT (cCBT) had positive effects for symptoms of anxiety (SMD -0.77, 95% Cl -1.45 to -0.09, k = 6, N = 220) and depression (SMD -0.62, 95% CI - 1.13 to -0.11, k = 7, N = 279). In a general population study of young people, there were small positive effects for anxiety (SMD -0.15, 95% Cl -0.26 to -0.03; N = 1273) and depression (SMD -0.15, 95% Cl -0.26 to -0.03; N = 1280). 

There was uncertainty around the effectiveness of cCBT in children (5-11 years). Evidence for other computerised interventions was sparse and inconclusive. Computerised CBT has potential for treating and preventing anxiety and depression in clinical and general populations of young people. 

Further program development and research is required to extend its use and establish its benefit in children. 

(C) 2015 Elsevier Ltd. All rights reserved.
AD  - [Pennant, Mary E.; Loucas, Christina E.; Whittington, Craig; Naqvi, Sabrina; Stockton, Sarah; Kendall, Tim] Royal Coll Psychiatrists, Natl Collaborating Ctr Mental Hlth, London E1 8BB, England. [Whittington, Craig; Fonagy, Peter] UCL, Res Dept Clin Educ &amp; Hlth Psychol, London, England. [Creswell, Cathy] Univ Reading, Sch Psychol &amp; Clin Language Sci, Reading RG6 2AH, Berks, England. [Fuggle, Peter] Anna Freud Ctr, London, England. [Kelvin, Raphael] Royal Coll Paediat &amp; Child Hlth, London, England. [Kelvin, Raphael] Univ Cambridge, Cambridge CB2 1TN, England. Pennant, ME (reprint author), Royal Coll Psychiatrists, Natl Collaborating Ctr Mental Hlth, 21 Prescot St, London E1 8BB, England. marypennant@outlook.com
AN  - WOS:000351886800001
AU  - Pennant,
AU  - M.
AU  - E.
AU  - Loucas,
AU  - C.
AU  - E.
AU  - Whittington,
AU  - C.
AU  - Creswell,
AU  - C.
AU  - Fonagy,
AU  - P.
AU  - Fuggle,
AU  - P.
AU  - Kelvin,
AU  - R.
AU  - Naqvi,
AU  - S.
AU  - Stockton,
AU  - S.
AU  - Kendall,
AU  - T.
AU  - the
AU  - Expert
AU  - Advisory
AU  - Group
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
J2  - Behav. Res. Ther.
KW  - Anxiety
KW  - Depression
KW  - Meta-analysis
KW  - Child psychology
KW  - Adolescent
KW  - psychology
KW  - Internet-delivered cognitive behaviour therapy
KW  - randomized controlled-trial
KW  - cognitive-behavioral therapy
KW  - mental-health-services
KW  - high-school-students
KW  - adolescent anxiety
KW  - bias
KW  - modification
KW  - psychological treatments
KW  - early intervention
KW  - social
KW  - anxiety
KW  - us children
KW  - Psychology
L1  - internal-pdf://2698616662/Pennant-2015-Computerised therapies for anxiet.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CE5PE Times Cited: 14 Cited Reference Count: 70 Pennant, Mary E. Loucas, Christina E. Whittington, Craig Creswell, Cathy Fonagy, Peter Fuggle, Peter Kelvin, Raphael Naqvi, Sabrina Stockton, Sarah Kendall, Tim Whittington, Craig/B-1380-2008; Whittington, Craig/0000-0002-1950-0334; Fonagy, Peter/0000-0003-0229-0091 U.K. Department of Health (DH); Child Health MindEd e-portal consortium; Medical Research Council; National Institute for Health and Care Excellence (NICE) This work was supported by the U.K. Department of Health (DH), via commission by the Royal College of Paediatrics and Child Health MindEd e-portal consortium. Dr. Creswell reports grants from the Medical Research Council, during the conduct of the study; and one of the included e-therapies (BRAVE for Teens online) has been made available free of charge for evaluation by her team. She is a member of the British Psychological Society (BPS) and British Association of Cognitive and Behavioural Psychotherapies (BABCP). Dr. Kelvin was seconded to the MindEd e-portal Consortium, as Consortium Clinical Lead and was previously (2009-2012) seconded to the Department of Health, England as National Advisor for Children and Adolescent Mental Health. Dr. Kendall is a grant holder for approximately 1.44 pound million per year from the National Institute for Health and Care Excellence (NICE) for guidelines work. He works with NICE International and undertakes some research into mental health, and the mental health workforce for the DH, Royal College of Psychiatrists and the academy of medical royal colleges. 14 15 74 Pergamon-elsevier science ltd Oxford 1873-622x
PY  - 2015
SP  - 1-18
T2  - Behaviour Research and Therapy
TI  - Computerised therapies for anxiety and depression in children and young people: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000351886800001
UR  - http://ac.els-cdn.com/S0005796715000169/1-s2.0-S0005796715000169-main.pdf?_tid=026e5b8c-04ce-11e7-ae53-00000aab0f01&amp;acdnat=1489067030_d93901bccc13dbe9bb560740ceeab647
VL  - 67
ER  -
TY  - JOUR
AB  - **Purpose: **
This review evaluates the evidence on the effects of brief strategic family therapy (BSFT) on drug use reduction for young people in treatment for nonopioid drug use. 

**Method:**
We followed Campbell Collaboration guidelines to prepare this review and ultimately located three studies for final analysis and interpretation. 

**Results: **
The results are mixed: BSFT does not seem to have better or worse effects on drug use frequency and family functioning than other treatments but has positive effects on treatment retention compared to control conditions. Longer retention in treatment has been identified as a consistent predictor of a favorable outcome from drug use treatment. 

**Discussion:** 
Although it is possible that the length of follow-up in the included studies was insufficient to detect significant changes, it should be noted that the evidence we found was limited, in terms of both the number of studies and their quality.
AD  - [Lindstrom, Maia; Filges, Trine; Jorgensen, Anne-Marie Klint] SFI Campbell, DK-1052 Copenhagen, Denmark. Filges, T (reprint author), SFI Campbell, Herluf Trolles Gade 11, DK-1052 Copenhagen, Denmark. tif@sfi.dk
AN  - WOS:000346719800005
AU  - Lindstrom,
AU  - M.
AU  - Filges,
AU  - T.
AU  - Jorgensen,
AU  - A.
AU  - M.
AU  - K.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1049731514530003
J2  - Res. Soc. Work. Pract.
KW  - abuse
KW  - systematic review
KW  - quantitative
KW  - meta-analysis
KW  - adolescent substance-abuse
KW  - use disorders
KW  - efficacy
KW  - trial
KW  - intervention
KW  - engagement
KW  - severity
KW  - lessons
KW  - youth
KW  - Social Work
L1  - internal-pdf://3000385504/Lindstrom-2015-Brief Strategic Family Therapy.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AX1PY Times Cited: 0 Cited Reference Count: 76 Lindstrom, Maia Filges, Trine Jorgensen, Anne-Marie Klint 0 3 14 Sage publications inc Thousand oaks 1552-7581
PY  - 2015
SP  - 61-80
T2  - Research on Social Work Practice
TI  - Brief Strategic Family Therapy for Young People in Treatment for Drug Use
UR  - &lt;Go to ISI&gt;://WOS:000346719800005
VL  - 25
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To evaluate the efficacy of massage on the short- and long-term outcomes of preterm infants. 

**METHODS:**
A search was conducted using the PRISMA framework. Validity of included studies was assessed using criteria defined by the Cochrane Collaboration that was carried out independently by two reviewers with a third reviewer to resolve differences. 

**RESULTS: **
Thirty-four studies met the inclusion criteria, 3 were quasi-experimental, 1 was a pilot study, and the remaining 30 were randomized controlled trials (RCTs). The outcomes that could be used in the meta-analysis and found in more than three studies noted that massage improved daily weight gain by 0.53 g (95% CI = 0.28-0.78), p &lt; 0.0001, and resulted in a significant improvement in mental scores by 7.89 points (95% CI = 0.96-14.82), p &lt; 0.03. There were no significant effects on length of hospital stay, caloric intake, or weight at discharge. Other outcomes were not analyzed either because the units of measurement varied or because means and standard deviations were not provided by the authors. These included vagal activity and heart rate variability (5 studies), neurobehavioral states (7 studies), pain responses (2 studies), maternal outcomes (2 studies), breastfeeding (2 studies), and physiologic parameters: bone formation (2 studies), immunologic markers (1 study), brain maturity (1 study), and temperature (1 study). The quality of the studies was variable with methods of randomization and blinding of assessment unclear in 18 of the 34 studies. 

**CONCLUSIONS: **
Massage therapy could be a comforting measure for infants in the NICU to improve weight gain and enhance mental development. However, the high heterogeneity, the weak quality in some studies, and the lack of a scientific association between massage and developmental outcomes preclude making definite recommendations and highlight the need for further RCTs to contribute to the existing body of knowledge.
AD  - Badr, Lina Kurdahi. Lina Kurdahi Badr is a Professor, Azusa Pacific University, Azusa, CA. The author can be reached via e-mail at linaKbadr@hotmail.com Bahia Abdallah is a Lecturer, Faculty of Health Sciences, University of Balamand, Ashrafieh, Beirut, Lebanon. The author can be reached at bahia.abdallah@balamand.edu.lb Lara Kahale, is a Research assistant, the Clinical Research Institute, American University of Beirut, Beirut, Lebanon.
AN  - 26302088
AU  - Badr,
AU  - L.
AU  - K.
AU  - Abdallah,
AU  - B.
AU  - Kahale,
AU  - L.
DA  - Nov-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/nmc.0000000000000177
DP  - Ovid Technologies
J2  - MCN Am J Matern Child Nurs
KW  - Humans
KW  - Infant, Newborn
KW  - Infant, Premature/gd [Growth &amp; Development]
KW  - Infant, Premature/px [Psychology]
KW  - *Infant, Premature
KW  - *Massage
L1  - internal-pdf://2398389594/Badr-2015-A Meta-Analysis of Preterm Infant Ma.pdf
LA  - English
M3  - Meta-Analysis
N1  - Badr, Lina Kurdahi Abdallah, Bahia Kahale, Lara
PY  - 2015
SP  - 344-58
T2  - MCN, American Journal of Maternal Child Nursing
TI  - A Meta-Analysis of Preterm Infant Massage: An Ancient Practice With Contemporary Applications
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26302088http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26302088&amp;id=doi:10.1097%2FNMC.0000000000000177&amp;issn=0361-929X&amp;isbn=&amp;volume=40&amp;issue=6&amp;spage=344&amp;pages=344-58&amp;date=2015&amp;title=MCN%2C+American+Journal+of+Maternal+Child+Nursing&amp;atitle=A+Meta-Analysis+of+Preterm+Infant+Massage%3A+An+Ancient+Practice+With+Contemporary+Applications.&amp;aulast=Badr&amp;pid=%3Cauthor%3EBadr+LK%3C%2Fauthor%3E%3CAN%3E26302088%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCDCCBEDAC00/fs046/ovft/live/gv023/00005721/00005721-201511000-00002.pdf
VL  - 40
ER  -
TY  - JOUR
AB  - **Background:** 
Undernutrition contributes to five million deaths of children under five each year. Furthermore, throughout the life cycle, undernutrition contributes to increased risk of infection, poor cognitive functioning, chronic disease, and mortality. It is thus important for decision-makers to have evidence about the effectiveness of nutrition interventions for young children.

**Objectives:** 
Primary objective1. To assess the effectiveness of supplementary feeding interventions, alone or with co-intervention, for improving the physical and psychosocial health of disadvantaged children aged three months to five years.Secondary objectives1. To assess the potential of such programmes to reduce socio-economic inequalities in undernutrition. 2. To evaluate implementation and to understand how this may impact on outcomes. 3. To determine whether there are any adverse effects of supplementary feeding.

**Search methods:** 
We searched CENTRAL, Ovid MEDLINE, PsycINFO, and seven other databases for all available years up to January 2014. We also searched ClinicalTrials.gov and several sources of grey literature. In addition, we searched the reference lists of relevant articles and reviews, and asked experts in the area about ongoing and unpublished trials.

**Selection criteria:** 
Randomised controlled trials (RCTs), cluster-RCTs, controlled clinical trials (CCTs), controlled before-and-after studies (CBAs), and interrupted time series (ITS) that provided supplementary food (with or without co-intervention) to children aged three months to five years, from all countries. Adjunctive treatments, such as nutrition education, were allowed. Controls had to be untreated.

**Data collection and analysis:** 
Two or more review authors independently reviewed searches, selected studies for inclusion or exclusion, extracted data, and assessed risk of bias. We conducted meta-analyses for continuous data using the mean difference (MD) or the standardised mean difference (SMD) with a 95% confidence interval (CI), correcting for clustering if necessary. We analysed studies from low- and middle-income countries and from high-income countries separately, and RCTs separately from CBAs. We conducted a process evaluation to understand which factors impact on effectiveness.

**Main results:** 
We included 32 studies (21 RCTs and 11 CBAs); 26 of these (16 RCTs and 10 CBAs) were in meta-analyses. More than 50% of the RCTs were judged to have low risk of bias for random selection and incomplete outcome assessment. We judged most RCTS to be unclear for allocation concealment, blinding of outcome assessment, and selective outcome reporting. Because children and parents knew that they were given food, we judged blinding of participants and personnel to be at high risk for all studies.Growth. Supplementary feeding had positive effects on growth in low- and middle-income countries. Meta-analysis of the RCTs showed that supplemented children gained an average of 0.12 kg more than controls over six months (95% confidence interval (CI) 0.05 to 0.18, 9 trials, 1057 participants, moderate quality evidence). In the CBAs, the effect was similar; 0.24 kg over a year (95% CI 0.09 to 0.39, 1784 participants, very low quality evidence). In high-income countries, one RCT found no difference in weight, but in a CBA with 116 Aboriginal children in Australia, the effect on weight was 0.95 kg (95% CI 0.58 to 1.33). For height, meta-analysis of nine RCTs revealed that supplemented children grew an average of 0.27 cm more over six months than those who were not supplemented (95% CI 0.07 to 0.48, 1463 participants, moderate quality evidence). Meta-analysis of seven CBAs showed no evidence of an effect (mean difference (MD) 0.52 cm, 95% CI -0.07 to 1.10, 7 trials, 1782 participants, very low quality evidence). Meta-analyses of the RCTs demonstrated benefits for weight-for-age z-scores (WAZ) (MD 0.15, 95% CI 0.05 to 0.24, 8 trials, 1565 participants, moderate quality evidence), and height-for-age z-scores (HAZ) (MD 0.15, 95% CI 0.06 to 0.24, 9 trials, 4638 participants, moderate quality evidence), bu not for weight-for-height z-scores MD 0.10 (95% CI -0.02 to 0.22, 7 trials, 4176 participants, moderate quality evidence). Meta-analyses of the CBAs showed no effects on WAZ, HAZ, or WHZ (very low quality evidence). We found moderate positive effects for haemoglobin (SMD 0.49, 95% CI 0.07 to 0.91, 5 trials, 300 participants) in a meta-analysis of the RCTs.Psychosocial outcomes. Eight RCTs in low- and middle-income countries assessed psychosocial outcomes. Our meta-analysis of two studies showed moderate positive effects of feeding on psychomotor development (SMD 0.41, 95% CI 0.10 to 0.72, 178 participants). The evidence of effects on cognitive development was sparse and mixed.We found evidence of substantial leakage. When feeding was given at home, children benefited from only 36% of the energy in the supplement. However, when the supplementary food was given in day cares or feeding centres, there was less leakage; children took in 85% of the energy provided in the supplement. Supplementary food was generally more effective for younger children (less than two years of age) and for those who were poorer/ less well-nourished. Results for sex were equivocal. Our results also suggested that feeding programmes which were given in day-care/feeding centres and those which provided a moderate-to-high proportion of the recommended daily intake (% RDI) for energy were more effective.

**Authors&#039; conclusions:** 
Feeding programmes for young children in low- and middle-income countries can work, but good implementation is key.
AN  - CD009924
AU  - Kristjansson,
AU  - E.
AU  - Francis,
AU  - D.
AU  - K.
AU  - Liberato,
AU  - S.
AU  - Benkhalti,
AU  - J.
AU  - M.
AU  - Welch,
AU  - V.
AU  - Batal,
AU  - M.
AU  - Greenhalgh,
AU  - T.
AU  - Rader,
AU  - T.
AU  - Noonan,
AU  - E.
AU  - Shea,
AU  - B.
AU  - Janzen,
AU  - L.
AU  - Wells,
AU  - G.
AU  - A.
AU  - Petticrew,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009924.pub2
KW  - Feeding Methods
KW  - Vulnerable Populations
KW  - Child Nutritional Physiological Phenomena
KW  - Controlled Before-After Studies
KW  - Energy Intake
KW  - Malnutrition [diet therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Sex Factors
KW  - Child, Preschool[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Male[checkword]
KW  - Behav
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Food supplementation for improving the physical and psychosocial health of socio-economically disadvantaged children aged three months to five years
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009924.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009924.pub2/asset/CD009924.pdf?v=1&amp;t=iw7jjf2u&amp;s=4faebceaecd92b85f374fcfd1d26a3242fb94dd8
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Preventing externalizing problems in children is a major societal concern, and a great number of intervention programs have been developed to this aim. To evaluate their preventive effects, well-controlled trials including follow-up assessments are necessary. 

**METHODS: **
This is a systematic review of the effect of prevention programs targeting externalizing problems in children. The review covered peer reviewed publications in English, German, French, Spanish and Scandinavian languages. Experimental studies of standardized programs explicitly aiming at preventing externalizing mental ill-health in children (2-19 years), with outcome assessments at &gt;6 months post intervention for both intervention and control groups, were included. We also included long-term trials with consecutive observations over several years, even in the absence of follow-up &gt;6 months post intervention. Studies of clinical populations or children with impairments, which substantially increase the risk for mental disorders, were excluded. 

**RESULTS: **
Thirty-eight controlled trials assessing 25 different programs met inclusion criteria. Only five programs were supported by scientific evidence, representing selective parent training (Incredible Years and Triple-P), indicated family support (Family Check-Up), and school-based programs (Good Behavior Game, universally delivered, and Coping Power, as an indicated intervention). With few exceptions, effects after 6-12 months were small. Long-term trials showed small and inconsistent effects. 

**CONCLUSIONS: **
Despite a vast literature, the evidence for preventive effects is meager, largely due to insufficient follow-up post intervention. Long-term follow up assessment and effectiveness studies should be given priority in future evaluations of interventions to prevent externalizing problems in children.
AD  - Smedler, Ann-Charlotte. Department of Psychology, Stockholm University, 10691 Stockholm, Sweden. Hjern, Anders. Centre for Health Equity Studies (CHESS), Stockholm University/Karolinska Institutet, Stockholm, Sweden ; Clinical Epidemiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden. Wiklund, Stefan. Department of Social Work, Stockholm University, Stockholm, Sweden. Anttila, Sten. The Swedish Council on Health Technology Assessment, Stockholm, Sweden. Pettersson, Agneta. The Swedish Council on Health Technology Assessment, Stockholm, Sweden ; LIME, Karolinska Institutet, Stockholm, Sweden.
AN  - 26696756
AU  - Smedler,
AU  - A.
AU  - C.
AU  - Hjern,
AU  - A.
AU  - Wiklund,
AU  - S.
AU  - Anttila,
AU  - S.
AU  - Pettersson,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10566-014-9281-y
DP  - Ovid Technologies
J2  - Child youth care forum
L1  - internal-pdf://0478330736/Smedler-2015-Programs for Prevention of Extern.pdf
LA  - English
N1  - Smedler, Ann-Charlotte Hjern, Anders Wiklund, Stefan Anttila, Sten Pettersson, Agneta 9281
PY  - 2015
SP  - 251-276
T2  - Child &amp; Youth Care Forum
TI  - Programs for Prevention of Externalizing Problems in Children: Limited Evidence for Effect Beyond 6 Months Post Intervention
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=26696756http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26696756&amp;id=doi:10.1007%2Fs10566-014-9281-y&amp;issn=1053-1890&amp;isbn=&amp;volume=44&amp;issue=2&amp;spage=251&amp;pages=251-276&amp;date=2015&amp;title=Child+%26+Youth+Care+Forum&amp;atitle=Programs+for+Prevention+of+Externalizing+Problems+in+Children%3A+Limited+Evidence+for+Effect+Beyond+6+Months+Post+Intervention.&amp;aulast=Smedler&amp;pid=%3Cauthor%3ESmedler+AC%3C%2Fauthor%3E%3CAN%3E26696756%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://download.springer.com/static/pdf/533/art%253A10.1007%252Fs10566-014-9281-y.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10566-014-9281-y&amp;token2=exp=1489068932~acl=%2Fstatic%2Fpdf%2F533%2Fart%25253A10.1007%25252Fs10566-014-9281-y.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10566-014-9281-y*~hmac=99a63b239ab090d1a26f38ea61cd5643af56384861c2db1100b7eab81fda6b43
VL  - 44
ER  -
TY  - JOUR
AB  - Anxiety is a common problem in children and adolescents with autism spectrum disorder (ASD). This meta-analysis aimed to systematically evaluate the evidence for the use of psychosocial interventions to manage anxiety in this population. 

Cognitive behavioural therapy (CBT) was the primary intervention modality studied. A comprehensive systematic search and study selection process was conducted. Separate statistical analyses were carried out for clinician-, parent-, and self-reported outcome measures. 

Sensitivity analyses were conducted by removing any outlying studies and any studies that did not use a CBT intervention. A subgroup analysis was performed to compare individual and group delivery of treatment. Ten randomised control trials involving a total of 470 participants were included. The overall SMD was d = 1.05 (95 % CI 0.45, 1.65; z = 3.45, p = 0.0006) for clinician-reported outcome measures; d = 1.00 (95% CI 0.21, 1.80; z = 2.47, p = 0.01) for parent-reported outcome measures; and d = 0.65 (95% CI -0.10, 1.07; z = 1.63, p = 0.10) for self-reported outcome measures. 

Clinician-and parent-reported outcome measures showed that psychosocial interventions were superior to waitlist and treatment-as-usual control conditions at post-treatment. However, the results of self-reported outcome measures failed to reach significance. 

The sensitivity analyses did not significantly change these results and the subgroup analysis indicated that individual treatment was more effective than group treatment. The main limitations of this review were the small number of included studies as well as the clinical and methodological variability between studies.
AD  - [Kreslins, Ance; Robertson, Ashley E.; Melville, Craig] Univ Glasgow, Inst Hlth &amp; Wellbeing, Gartnavel Royal Hosp, 1st Floor Admin Bldg,1055 Great Western Rd, Glasgow G12 0XH, Lanark, Scotland. Robertson, AE (reprint author), Univ Glasgow, Inst Hlth &amp; Wellbeing, Gartnavel Royal Hosp, 1st Floor Admin Bldg,1055 Great Western Rd, Glasgow G12 0XH, Lanark, Scotland. ashleyerobertson@icloud.com
AN  - WOS:000370939800001
AU  - Kreslins,
AU  - A.
AU  - Robertson,
AU  - A.
AU  - E.
AU  - Melville,
AU  - C.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/s13034-015-0054-7
J2  - Child Adolesc. Psychiatry Ment. Health
KW  - Meta-analysis
KW  - Autism spectrum disorder/ASD
KW  - Anxiety
KW  - Child
KW  - Adolescent
KW  - Psychosocial intervention
KW  - Cognitive behavioural therapy/CBT
KW  - randomized controlled-trial
KW  - cognitive-behavioral therapy
KW  - social-interaction
KW  - asperger-syndrome
KW  - prevalence
KW  - youth
KW  - classification
KW  - epidemiology
KW  - comorbidity
KW  - symptoms
KW  - Pediatrics
KW  - Psychiatry
L1  - internal-pdf://0958607424/Kreslins.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DE9EV Times Cited: 2 Cited Reference Count: 54 Kreslins, Ance Robertson, Ashley E. Melville, Craig Robertson, Ashley/0000-0001-9914-3199 2 5 14 Biomed central ltd London 1753-2000
PY  - 2015
SP  - 12
T2  - Child and Adolescent Psychiatry and Mental Health
TI  - The effectiveness of psychosocial interventions for anxiety in children and adolescents with autism spectrum disorder: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000370939800001
UR  - http://download.springer.com/static/pdf/948/art%253A10.1186%252Fs13034-015-0044-9.pdf?originUrl=http%3A%2F%2Fcapmh.biomedcentral.com%2Farticle%2F10.1186%2Fs13034-015-0044-9&amp;token2=exp=1489065524~acl=%2Fstatic%2Fpdf%2F948%2Fart%25253A10.1186%25252Fs13034-015-0044-9.pdf*~hmac=9eac034080ccc49918aa7d0915acd6e1fc5e0e80e6181a190a986d868c0eb1ce
VL  - 9
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
School refusal is a psychosocial problem characterized by a student&rsquo;s difficulty attending school and, in many cases, substantial absence from school (Heyne &amp; Sauter, 2013). It is often distinguished from truancy, in part because of the severe emotional distress associated with having to attend school and the absence of severe antisocial behavior. Truancy, on the other hand, is not typically associated with emotional distress and is commonly associated with severe externalizing behavior. The emotional distress associated with school refusal is often in the form of fear or anxiety, and sometimes in the form of depression. School refusal occurs for about 1-2% of young people, and estimates among clinically referred youth are considerably higher. There is substantial heterogeneity in both the presentation of school refusal and its associated risk factors. Significant adverse consequences may occur in the short- and long-term, including school dropout and problems with social adjustment. Family members and school staff are also affected by school refusal. The most commonly studied interventions for school refusal are behavioral approaches and cognitive-behavioral therapy (CBT). The overarching aim of these interventions is the reduction of the young person&rsquo;s emotional distress and an increase in school attendance to help the young person follow a normal developmental pathway (Heyne &amp; Sauter, 2013). Behavioral interventions include exposure-based interventions, relaxation training, and/or social skills training with the student, and contingency management procedures with the parents and school staff. CBT manuals additionally focus attention on the identification and modification of maladaptive cognition that may maintain the young person&rsquo;s emotional distress and absenteeism. In some instances parent cognition is also targeted. Other interventions have been used to treat school refusal (e.g., psychodynamic treatment, family therapy, medication) but CBT has been the most studied intervention and most prior reviews have focused on CBT and/or behavioral interventions. While prior reviews have found some support for CBT and behavioral interventions for reducing anxiety and/or improving attendance, the reviews have been mixed (Maynard et al., 2013). Prior reviews have also been limited to published research, have not adequately assessed the quality of evidence, and have primarily employed either qualitative or vote-counting methods for synthesizing study outcomes. No prior meta-analysis of interventions targeting school refusal has been located. 

**OBJECTIVES** 
The purpose of this review was to inform practice and policy by evaluating the effects of psychosocial interventions for school refusal. The following research questions guided this study: 1) Do psychosocial interventions targeting school refusal reduce anxiety? 2) Do psychosocial interventions targeting school refusal increase attendance? 

**SEARCH METHODS** 
Electronic searches were conducted in 15 databases and 4 research registers, and internet searches were conducted for conference proceedings and other grey literature. Searches were conducted using the following keywords: (anxiety OR &ldquo;school refus*&rdquo; OR &ldquo;school phobia&rdquo;) AND (attendance OR absen*) AND (evaluation OR intervention OR treatment OR outcome OR program) AND (student* OR school* OR child* OR adolescen*). Reviews of reference lists of included studies and prior reviews and personal contact with authors of prior studies of school refusal were also conducted to identify potential studies for this review. 

**SELECTION CRITERIA** 
Published or unpublished studies assessing effects of psychosocial interventions to improve attendance or reduce anxiety with school-age youth who met criteria for school refusal were included in this review. To be eligible for inclusion in this review, studies must have been conducted or reported between January 1980 and November 2013 and employed an experimental or quasi-experimental design. In addition, studies must have used statistical controls or reported baseline dat o outcomes regardless of study design. Studies that assessed effects of medications only or studies conducted in residential treatment centers were excluded from this review. 

**DATA COLLECTION AND ANALYSIS** 
Titles and abstracts of the studies found through the search procedures were screened for relevance, and those that were obviously ineligible or irrelevant were screened out. Documents that were not obviously ineligible or irrelevant based on the abstract review were retrieved in full text for final eligibility screening. Two reviewers independently screened the full-text articles for inclusion. Studies that met eligibility criteria were coded independently by two coders. Two review authors also independently assessed the risk of bias in each study using the Cochrane Collaboration&rsquo;s &lsquo;Risk of Bias&rsquo; tool (Higgins et al., 2011). Coders met to review the coding agreement and any discrepancies were discussed and resolved by consensus. Effect sizes were calculated in Comprehensive Meta-Analysis (CMA) version 2.0 (Borenstein, Hedges, Higgins, &amp; Rothstein, 2005). We adjusted for differences at baseline by computing the pre-test effect size and subtracting it from the post-test effect size. The standardized mean difference effect size statistic, employing Hedges&rsquo; g to correct for small sample size bias (Hedges, 1981), was used. When an author used more than one measure of an outcome, an effect size was calculated for each measure and a mean ES was calculated so each study contributed only one effect size per study for each outcome. Four meta-analyses were performed; two meta-analyses were performed to synthesize studies assessing effects of psychosocial interventions on anxiety and attendance and two were performed to synthesize effects of studies assessing effects of medication in combination with psychotherapy on anxiety and attendance. A weighted mean effect was calculated by weighting each study by the inverse of its variance using random effects statistical models. We assessed statistical heterogeneity using the Q-test and I2 statistic. Several moderator and sensitivity analyses were planned, but due to the small number of studies included in this review and lack of heterogeneity, we limited additional analyses performed. 

**RESULTS** 
A total of eight studies examining effects of interventions on anxiety or attendance with 435 school-age participants exhibiting school refusal were included in this review. Six studies examining effects of psychosocial interventions and two studies assessing comparative effects of psychosocial interventions with and without medication met inclusion criteria for this review. Six of the included studies were randomized controlled trials (RCT) and two were quasi-experimental design (QED) studies. The majority (75%) of the studies were published in peer-reviewed journals. Five of the interventions took place in a clinic setting, one in the school, one in the school and home and one in an undisclosed setting. All but one of the six psychosocial intervention studies in this review assessed the effects of a variant of cognitive-behavioral therapy (CBT) compared to no treatment control (k = 1), an unspecified control (k = 1) or alternative treatment control group (k = 4). For the two studies assessing effects of medication, the same CBT intervention was applied across treatment and control groups with either Fluoxetine or imipramine as the treatment and placebo or no placebo as the control. The mean effect of the psychosocial interventions at post-test on anxiety was g = 0.06 (95% CI [-0.63, 0.75], p = .86), demonstrating a non-significant effect. The homogeneity analysis indicated a moderate degree of heterogeneity (Q = 11.13, p = .01, I2 = 73.05%, &tau;2 = .36). Effects on attendance were significant (g = 0.54 (95% CI [0.22, 0.86], p = .00). The homogeneity analysis indicated a small degree of heterogeneity (Q = 8.82, p = .12, I2 = 43.32%, &tau;2 = .06). Similar results were found for the mean effects of medication + CBT studies, with effects on anxiety being not significant (g= -0.05, 95% CI [-0 40, 0. 1], p = .80) and effects on attendance being positive and statistically significant (g = 0.61 (95% CI [0.01, 1.21], p = .046). Studies were homogenous for the medication + CBT studies for both anxiety (Q = .30, p = .58; I2 = 0.00% and &tau;2 = .00) and attendance (Q = 1.93, p = .17, I2 = 48.23%; &tau;2 = .09). 

**AUTHORS&rsquo; CONCLUSIONS** 
The present review found relatively few rigorous studies of interventions for school refusal. Seven of the eight included studies assessed effects of a variant of cognitive behavioral therapy (CBT), thus there appears to be a lack of rigorous evidence of non-CBT interventions for school refusal. Findings of the current review were mixed. While both the CBT only and CBT plus medication interventions found, on average, positive and significant effects on attendance compared to control, effects on anxiety at post-test across both sets of studies were not significantly different from zero. Moreover, the magnitude of treatment effects on anxiety varied across the psychosocial only studies, and thus current estimates of treatment effects should be evaluated with caution. The current evidence provides tentative support for CBT in the treatment of school refusal, but there is an overall lack of sufficient evidence to draw firm conclusions of the efficacy of CBT as the treatment of choice for school refusal. Most of the studies in this review compared effects against other, and sometimes very similar, interventions that could mask larger effects if compared to wait list control or other disparate interventions. Furthermore, most studies only measured immediate effects of interventions; only one study reported comparative longer-term effects on both attendance and anxiety. Thus, there is insufficient evidence to indicate whether or not treatment effects sustain, and whether or not anxiety might further decrease over time with continued exposure to school. Several risks of bias were present in most studies included in this review, particularly related to blinding of participants and assessors, which must be considered when interpreting the results of this review. Performance and detection bias resulting from inadequate blinding of participants and assessors to condition could upwardly bias the mean effects. In addition, insufficient details related to random sequence generation and allocation concealment were provided to adequately assess selection bias in most studies, and two studies reported non-random allocation to condition. While most studies in this review reported to use random assignment procedures, it is uncertain whether selection bias is present due to inadequate generation of randomization or concealment of allocation prior to assignment. The few rigorous studies found for this review and the risks of bias present in most of the included studies indicate a need for better-controlled studies. Moreover, independent replications of the manualized interventions examined in this review are needed, as are longer-term evaluations of effects of interventions. Assessing long-term effects could provide additional answers and insights as to the mixed findings of the effects of interventions on attendance and anxiety. Future studies should also consider other types of interventions for rigorous evaluation. Furthermore, future studies could benefit from larger sample sizes and attention to mitigating potential biases to improve statistical power and causal inference.
AU  - Maynard,
AU  - B.
AU  - R.
AU  - Brendel,
AU  - K.
AU  - Bulanda,
AU  - J.
AU  - J.
AU  - Heyne,
AU  - D.
AU  - Thompson,
AU  - A.
AU  - Pigott,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2015.12
PY  - 2015
T2  - Campbell Systematic Reviews
TI  - Psychosocial Interventions for School Refusal with Primary and Secondary School Students: A Systematic Review
ER  -
TY  - JOUR
AB  - Sensory-based therapies are designed to address sensory processing difficulties by helping to organize and control the regulation of environmental sensory inputs. 
These treatments are increasingly popular, particularly with children with behavioral and developmental disabilities. 

However, empirical support for sensory-based treatments is limited. The purpose of this review was to conduct a comprehensive and methodologically sound evaluation of the efficacy of sensory-based treatments for children with disabilities. 

Methods for this review were registered with PROSPERO (CRD42012003243). Thirty studies involving 856 participants met our inclusion criteria and were included in this review. Considerable heterogeneity was noted across studies in implementation, measurement, and study rigor. 

The research on sensory-based treatments is limited due to insubstantial treatment outcomes, weak experimental designs, or high risk of bias. 

Although many people use and advocate for the use of sensory-based treatments and there is a substantial empirical literature on sensory-based treatments for children with disabilities, insufficient evidence exists to support their use. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Barton, Erin E.: erin.e.barton@vanderbilt.edu Barton, Erin E.: Vanderbilt University, 230 Appleton Place, Peabody 228, Nashville, TN, US, 37203, erin.e.barton@vanderbilt.edu Barton, Erin E.: Vanderbilt University, Nashville, TN, US Reichow, Brian: University of Florida, Gainesville, FL, US Schnitz, Alana: Vanderbilt University, Nashville, TN, US Smith, Isaac C.: Yale Child Study Center, CT, US Sherlock, Daniel: Vanderbilt University, Nashville, TN, US
AN  - 2015-05377-010
AU  - Barton,
AU  - E.
AU  - E.
AU  - Reichow,
AU  - B.
AU  - Schnitz,
AU  - A.
AU  - Smith,
AU  - I.
AU  - C.
AU  - Sherlock,
AU  - D.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ridd.2014.11.006
DP  - Ovid Technologies
KW  - Childhood developmental disorders, Intellectual disability, Autism spectrum disorder, Systematic review, mental retardation
KW  - *Childhood Development
KW  - *Developmental Disabilities
KW  - *Intellectual Development Disorder
KW  - Literature Review
KW  - Developmental Disorders &amp; Autism [3250]
KW  - Medical Treatment of Physical Illness [3363]
KW  - Child
KW  - Child Development Disorders, Pervasive
KW  - Cognition Disorders
KW  - Developmental Disabilities
KW  - Humans
KW  - Intellectual Disability
KW  - Occupational Therapy
KW  - Sensation Disorders
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://1104644746/Barton-2015-A systematic review of sensory-bas.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2015
SP  - 64-80
T2  - Research in Developmental Disabilities
TI  - A systematic review of sensory-based treatments for children with disabilities
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-05377-010http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.ridd.2014.11.006&amp;issn=0891-4222&amp;isbn=&amp;volume=37&amp;issue=&amp;spage=64&amp;pages=64-80&amp;date=2015&amp;title=Research+in+Developmental+Disabilities&amp;atitle=A+systematic+review+of+sensory-based+treatments+for+children+with+disabilities.&amp;aulast=Barton&amp;pid=%3Cauthor%3EBarton%2C+Erin+E%3C%2Fauthor%3E%3CAN%3E2015-05377-010%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S089142221400482X/1-s2.0-S089142221400482X-main.pdf?_tid=36f275c0-04c2-11e7-a7a2-00000aacb35f&amp;acdnat=1489061965_68f1a6f830f9db7881f381713d302bf8
VL  - 37
ER  -
TY  - JOUR
AB  - **Objective: **
The outcome of institutional youth care for children is heavily debated. This multilevel meta-analysis aims to address the outcome of institutional youth care compared to non-institutional youth care for children of primary school age and early adolescence in economically developed countries. A gain of knowledge in this area may help the decision for referral of children to institutional youth care or other types of care (e.g., foster care or community-based care), and improve outcomes for children in youth care. 

**Methods: **
Of 19 controlled studies (15.526 participants), 63 effect sizes of behaviour problems (externalizing, internalizing, and total), skills (social and cognitive) and delinquency were computed based on comparisons between institutional Evidence-Based Treatment (EBT), institutional Care As Usual (CAU), non-institutional EBT, and non-institutional CAU. 

**Results: **
Institutional CAU showed a small-to-medium negative significant effect compared to non-institutional CAU (d = -0.342). Furthermore, children in institutional care showed slightly more delinquent behaviour compared to children in non-institutional care (d = -0.329). Significant moderating effects were also found for study design, year of publication and sex of the child. 

**Conclusions: **
Children receiving non-institutional CAU (mostly foster care) had slightly better outcomes than children in institutional CAU (regular group care). No differences were found between institutional and non-institutional care when institutional treatment was evidence-based. More research is needed on the conditions that make established treatment methods work in institutional care for (young) children. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - L. l A. m J. j. m B H. p J. w Strijbosch, E. L. L.: e.strijbosch@juzt.nl; Stams, G. J. J. M.: g.j.j.m.stams@uva.nl; Wissink, I. B.: i.b.wissink@uva.nl; van der Helm, G. H. P.: helm.vd.p@hsleiden.nl Strijbosch, E. L. L.: Quality and Innovation Unit at Juzt, Erasmusweg 34, Breda, Netherlands, 4834 AA Strijbosch, E. L. L.: Juzt (Quality and Innovation unit), Breda, Netherlands Huijs, J. A. M.: University of Amsterdam, Department of Forensic Child and Youth Care Sciences, Amsterdam, Netherlands Stams, G. J. J. M.: University of Amsterdam, Department of Forensic Child and Youth Care Sciences, Amsterdam, Netherlands Wissink, I. B.: University of Amsterdam, Department of Forensic Child and Youth Care Sciences, Amsterdam, Netherlands van der Helm, G. H. P.: Leiden University of Applied Sciences, Youth Expert Centre, Leiden, Netherlands de Swart, J. J. W.: Windesheim University of Applied Sciences, Zwolle, Netherlands van der Veen, Z.: University of Amsterdam, Department of Forensic Child and Youth Care Sciences, Amsterdam, Netherlands
AN  - 2015-50502-026
AU  - Strijbosch,
AU  - E.
AU  - Huijs,
AU  - J.
AU  - Stams,
AU  - G.
AU  - Wissink,
AU  - I.
AU  - van
AU  - der
AU  - Helm,
AU  - G.
AU  - de,
AU  - Swart,
AU  - J.
AU  - van
AU  - der
AU  - Veen,
AU  - Z.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2015.09.018
DP  - Ovid Technologies
KW  - Institutional youth care, Outcome, Meta-analysis, Primary school age, Early adolescence, Evidence-based treatment
KW  - *Community Services
KW  - *Foster Care
KW  - *Institutionalization
KW  - *Junior High School Students
KW  - *Primary School Students
KW  - Developed Countries
KW  - Community &amp; Social Services [3373]
KW  - Human Childhood (birth-12 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://0219990699/Strijbosch-2015-The outcome of institutional y.pdf
LA  - English
M3  - Meta Analysis
PY  - 2015
SP  - 208-218
T2  - Children and Youth Services Review
TI  - The outcome of institutional youth care compared to non-institutional youth care for children of primary school age and early adolescence: A multi-level meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-50502-026http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2015.09.018&amp;issn=0190-7409&amp;isbn=&amp;volume=58&amp;issue=&amp;spage=208&amp;pages=208-218&amp;date=2015&amp;title=Children+and+Youth+Services+Review&amp;atitle=The+outcome+of+institutional+youth+care+compared+to+non-institutional+youth+care+for+children+of+primary+school+age+and+early+adolescence%3A+A+multi-level+meta-analysis.&amp;aulast=Strijbosch&amp;pid=%3Cauthor%3EStrijbosch%2C+E.+L.+L%3C%2Fauthor%3E%3CAN%3E2015-50502-026%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0190740915300645/1-s2.0-S0190740915300645-main.pdf?_tid=85269592-04d0-11e7-a72d-00000aacb361&amp;acdnat=1489068109_19fa8f9b3081b793b36b03d6632237e9
VL  - 58
ER  -
TY  - JOUR
AB  - **Background:**
A previous Cochrane review (James 2005) showed that cognitive behavioural therapy (CBT) was effective in treating childhood anxiety disorders; however, questions remain regarding (1) the relative efficacy of CBT versus non-CBT active treatments; (2) the relative efficacy of CBT versus medication and the combination of CBT and medication versus placebo; and (3) the long-term effects of CBT.&nbsp;

**Objectives:** 
To examine (1) whether CBT is an effective treatment for childhood and adolescent anxiety disorders in comparison with (a) wait-list controls; (b) active non-CBT treatments (i.e. psychological placebo, bibliotherapy and treatment as usual (TAU)); and (c) medication and the combination of medication and CBT versus placebo; and (2) the long-term effects of CBT.Search methods: Searches for this review included the Cochrane Central Register of Controlled Trials (CENTRAL) and the Cochrane Depression, Anxiety and Neurosis Group Register, which consists of relevant randomised controlled trials from the bibliographic databases?The Cochrane Library (1970 to July 2012), EMBASE, (1970 to July 2012) MEDLINE (1970 to July 2012) and PsycINFO (1970 to July 2012).

**Selection criteria:** 
All randomised controlled trials (RCTs) of CBT versus waiting list, active control conditions, TAU or medication were reviewed. All participants must have met the criteria of the Diagnostic and Statistical Manual (DSM) or the International Classification of Diseases (ICD) for an anxiety diagnosis, excluding simple phobia, obsessive-compulsive disorder, post-traumatic stress disorder and elective mutism.

**Data collection and analysis:** 
The methodological quality of included trials was assessed by three reviewers independently. For the dichotomous outcome of remission of anxiety diagnosis, the odds ratio (OR) with 95% confidence interval (CI) based on the random-effects model, with pooling of data via the inverse variance method of weighting, was used. Significance was set at P &lt; 0.05. Continuous data on each child?s anxiety symptoms were pooled using the standardised mean difference (SMD).

**Main results:**
Forty-one studies consisting of 1806 participants were included in the analyses. The studies involved children and adolescents with anxiety of mild to moderate severity in university and community clinics and school settings. For the primary outcome of remission of any anxiety diagnosis for CBT versus waiting list controls, intention-to-treat (ITT) analyses with 26 studies and 1350 participants showed an OR of 7.85 (95% CI 5.31 to 11.60, Z = 10.26, P &lt; 0.0001), but with evidence of moderate heterogeneity (P = 0.04, I&sup2; = 33%). The number needed to treat (NNT) was 6.0 (95% CI 7.5 to 4.6). No difference in outcome was noted between individual, group and family/parental formats. ITT analyses revealed that CBT was no more effective than non-CBT active control treatments (six studies, 426 participants) or TAU in reducing anxiety diagnoses (two studies, 88 participants). The few controlled follow-up studies (n = 4) indicate that treatment gains in the remission of anxiety diagnosis are not statistically significant.

**Authors&#039; conclusions:** 
Cognitive behavioural therapy is an effective treatment for childhood and adolescent anxiety disorders; however, the evidence suggesting that CBT is more effective than active controls or TAU or medication at follow-up, is limited and inconclusive.
AN  - CD004690
AU  - James,
AU  - A.
AU  - C.
AU  - James,
AU  - G.
AU  - Cowdrey,
AU  - F.
AU  - A.
AU  - Soler,
AU  - A.
AU  - Choke,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004690
KW  - Cognitive Therapy
KW  - Anxiety Disorders [therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive behavioural therapy for anxiety disorders in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004690.pub4/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004690.pub4/asset/CD004690.pdf?v=1&amp;t=iw7j4amy&amp;s=740b73814422563592cfdf300efd3e18331fac0e
ER  -
TY  - JOUR
AB  - **Background:** 
Parent-infant psychotherapy (PIP) is a dyadic intervention that works with parent and infant together, with the aim of improving the parent-infant relationship and promoting infant attachment and optimal infant development. PIP aims to achieve this by targeting the mother?s view of her infant, which may be affected by her own experiences, and linking them to her current relationship to her child, in order to improve the parent-infant relationship directly.

**Objectives:**
1. To assess the effectiveness of PIP in improving parental and infant mental health and the parent-infant relationship.2. To identify the programme components that appear to be associated with more effective outcomes and factors that modify intervention effectiveness (e.g. programme duration, programme focus).

**Search methods:** 
We searched the following electronic databases on 13 January 2014: Cochrane Central Register of Controlled Trials (CENTRAL, 2014, Issue 1), Ovid MEDLINE, EMBASE, CINAHL, PsycINFO, BIOSIS Citation Index, Science Citation Index, ERIC, and Sociological Abstracts. We also searched the metaRegister of Controlled Trials, checked reference lists, and contacted study authors and other experts.

**Selection criteria:** 
Two review authors assessed study eligibility independently. We included randomised controlled trials (RCT) and quasi-randomised controlled trials (quasi-RCT) that compared a PIP programme directed at parents with infants aged 24 months or less at study entry, with a control condition (i.e. waiting-list, no treatment or treatment-as-usual), and used at least one standardised measure of parental or infant functioning. We also included studies that only used a second treatment group.

**Data collection and analysis:** 
We adhered to the standard methodological procedures of The Cochrane Collaboration. We standardised the treatment effect for each outcome in each study by dividing the mean difference (MD) in post-intervention scores between the intervention and control groups by the pooled standard deviation. We presented standardised mean differences (SMDs) and 95% confidence intervals (CI) for continuous data, and risk ratios (RR) for dichotomous data. We undertook meta-analysis using a random-effects model.

**Main results:** 
We included eight studies comprising 846 randomised participants, of which four studies involved comparisons of PIP with control groups only. Four studies involved comparisons with another treatment group (i.e. another PIP, video-interaction guidance, psychoeducation, counselling or cognitive behavioural therapy (CBT)), two of these studies included a control group in addition to an alternative treatment group. Samples included women with postpartum depression, anxious or insecure attachment, maltreated, and prison populations. We assessed potential bias (random sequence generation, allocation concealment, incomplete outcome data, selective reporting, blinding of participants and personnel, blinding of outcome assessment, and other bias). Four studies were at low risk of bias in four or more domains. Four studies were at high risk of bias for allocation concealment, and no study blinded participants or personnel to the intervention. Five studies did not provide adequate information for assessment of risk of bias in at least one domain (rated as unclear).Six studies contributed data to the PIP versus control comparisons producing 19 meta-analyses of outcomes measured at post-intervention or follow-up, or both, for the primary outcomes of parental depression (both dichotomous and continuous data); measures of parent-child interaction (i.e. maternal sensitivity, child involvement and parent engagement; infant attachment category (secure, avoidant, disorganised, resistant); attachment change (insecure to secure, stable secure, secure to insecure, stable insecure); infant behaviour and secondary outcomes (e.g. infant cognitive development). The results favoured neither PIP nor control for incidence of parental depression (RR 0.74, 95% CI 0.52 to 1.04, 3 studies, 278 participants, low quality evidence) or parent-rep r ed levels of depression (SMD -0.22, 95% CI -0.46 to 0.02, 4 studies, 356 participants, low quality evidence). There were improvements favouring PIP in the proportion of infants securely attached at post-intervention (RR 8.93, 95% CI 1.25 to 63.70, 2 studies, 168 participants, very low quality evidence); a reduction in the number of infants with an avoidant attachment style at post-intervention (RR 0.48, 95% CI 0.24 to 0.95, 2 studies, 168 participants, low quality evidence); fewer infants with disorganised attachment at post-intervention (RR 0.32, 95% CI 0.17 to 0.58, 2 studies, 168 participants, low quality evidence); and an increase in the proportion of infants moving from insecure to secure attachment at post-intervention (RR 11.45, 95% CI 3.11 to 42.08, 2 studies, 168 participants, low quality evidence). There were no differences between PIP and control in any of the meta-analyses for the remaining primary outcomes (i.e. adverse effects), or secondary outcomes.Four studies contributed data at post-intervention or follow-up to the PIP versus alternative treatment analyses producing 15 meta-analyses measuring parent mental health (depression); parent-infant interaction (maternal sensitivity); infant attachment category (secure, avoidant, resistant, disorganised) and attachment change (insecure to secure, stable secure, secure to insecure, stable insecure); infant behaviour and infant cognitive development. None of the remaining meta-analyses of PIP versus alternative treatment for primary outcomes (i.e. adverse effects), or secondary outcomes showed differences in outcome or any adverse changes.We used the Grades of Recommendation, Assessment, Development and Evaluation Working Group (GRADE) approach to rate the overall quality of the evidence. For all comparisons, we rated the evidence as low or very low quality for parental depression and secure or disorganised infant attachment. Where we downgraded the evidence, it was because there was risk of bias in the study design or execution of the trial. The included studies also involved relatively few participants and wide CI values (imprecision), and, in some cases, we detected clinical and statistical heterogeneity (inconsistency). Lower quality evidence resulted in lower confidence in the estimate of effect for those outcomes.

**Authors&#039; conclusions:** 
Although the findings of the current review suggest that PIP is a promising model in terms of improving infant attachment security in high-risk families, there were no significant differences compared with no treatment or treatment-as-usual for other parent-based or relationship-based outcomes, and no evidence that PIP is more effective than other methods of working with parents and infants. Further rigorous research is needed to establish the impact of PIP on potentially important mediating factors such as parental mental health, reflective functioning, and parent-infant interaction.
AN  - CD010534
AU  - Barlow,
AU  - J.
AU  - Bennett,
AU  - C.
AU  - Midgley,
AU  - N.
AU  - Larkin,
AU  - S.
AU  - Wei,
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd010534.pub2
KW  - Behav
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Parent-infant psychotherapy for improving parental and infant mental health
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD010534.pub2/abstract
ER  -
TY  - JOUR
AB  - **Background **
Studies report contrasting results regarding the efficacy and safety of pharmacological, psychological, and combined interventions in psychosis and schizophrenia in children, adolescents and young adults. 

**Methods **
Systematic review and meta-analysis. Embase, Medline, PreMedline, PsycINFO, and CENTRAL were searched to July 2013 without restriction to publication status. Randomised trials comparing any pharmacological, psychological, or combined intervention for psychosis and schizophrenia in children, adolescents and young adults were included. Studies were assessed for bias, and GRADE criteria were used to describe the quality of the results. 

**Results **
Twenty-seven trials including 3067 participants were identified. Meta-analyses were performed for 12 comparisons: symptoms, relapse, global state, psychosocial functioning, depression, weight and discontinuation. Low quality evidence demonstrated that antipsychotics have small beneficial effects on psychotic symptoms (SMD = -0.42, 95% CI -0.58 to -0.26), and a medium adverse effect on weight gain (WMD = 1.61, 95% CI 0.61 to 2.60) and discontinuation due to side effects (RR = 2.44, 95% CI, 1.12 to 5.31). There were no trials of psychological treatments in under-18 year olds. There was no evidence of an effect of psychological interventions on psychotic symptoms in an acute episode, or relapse rate, but low quality evidence of a large effect for family plus individual CBT on the number of days to relapse (WMD = 32.25, 95% CI -36.52 to -27.98). 

**Conclusions **
For children, adolescents and young adults, the balance of risk and benefit of antipsychotics appears less favourable than in adults. Research is needed to establish the potential for psychological treatments, alone and in combination with antipsychotics, in this population.
AD  - [Stafford, Megan R.; Loucas, Christina E.; Kendall, Tim] Royal Coll Psychiatrists, NCCMH, London SW1X 8PG, England. [Mayo-Wilson, Evan] UCL, CORE, London, England. [James, Anthony] Warneford Hosp, Highfield Adolescent Unit, Oxford OX3 7JX, England. [Hollis, Chris] Queens Med Ctr, Fac Med &amp; Hlth Sci, Nottingham NG7 2UH, England. [Birchwood, Max] Univ Warwick, Warwick Med Sch, Div Mental Hlth &amp; Wellbeing, Coventry CV4 7AL, W Midlands, England. Kendall, T (reprint author), Royal Coll Psychiatrists, NCCMH, London SW1X 8PG, England. tim2.kendall@virgin.net
AN  - WOS:000349545300037
AU  - Stafford,
AU  - M.
AU  - R.
AU  - Mayo-Wilson,
AU  - E.
AU  - Loucas,
AU  - C.
AU  - E.
AU  - James,
AU  - A.
AU  - Hollis,
AU  - C.
AU  - Birchwood,
AU  - M.
AU  - Kendall,
AU  - T.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
J2  - PLoS One
KW  - randomized controlled-trial
KW  - early-onset schizophrenia
KW  - placebo-controlled trial
KW  - double-blind
KW  - 1st-episode psychosis
KW  - 2nd-generation antipsychotics
KW  - schizoaffective disorder
KW  - spectrum
KW  - disorders
KW  - clinical-trials
KW  - 1st episode
KW  - Science &amp; Technology - Other Topics
L1  - internal-pdf://0341624687/Stafford-2015-Efficacy and Safety of Pharmacol.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CB3RF Times Cited: 6 Cited Reference Count: 72 Stafford, Megan R. Mayo-Wilson, Evan Loucas, Christina E. James, Anthony Hollis, Chris Birchwood, Max Kendall, Tim Hollis, Chris/0000-0003-1083-6744 National Collaborating Centre for Mental Health This work was supported by the National Collaborating Centre for Mental Health and conducted as part of a guideline about psychosis in children, adolescents and young adults. The full review protocol is available from the authors. TK receives 1.4 pound million per year for the National Collaborating Centre for Mental Health from the National Institute for Health and Clinical Excellence to develop guidelines for the treatment of mental health problems (https://www.nice.org.uk/). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. 6 30 74 Public library science San francisco
PY  - 2015
SP  - 17
T2  - Plos One
TI  - Efficacy and Safety of Pharmacological and Psychological Interventions for the Treatment of Psychosis and Schizophrenia in Children, Adolescents and Young Adults: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000349545300037
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117166&amp;type=printable
VL  - 10
ER  -
TY  - JOUR
AB  - **Objectives: **
Sound evaluations of sexual offender treatment are essential for an evidence-based crime policy. However, previous reviews substantially varied in their mean effects and were often based on methodologically weak primary studies. Therefore, the present study contains an update of our meta-analysis in the first issue of this journal (Losel and Schmucker Journal of Experimental Criminology, 1, 117-146, 2005). It includes more recent primary research and is restricted to comparisons with equivalent treatment and control groups and official measures of recidivism as outcome criteria.

**Methods: **
Applying a detailed search procedure which yielded more than 3000 published and unpublished documents, we identified 29 eligible comparisons containing a total of 4,939 treated and 5,448 untreated sexual offenders. The study effects were integrated using a random effects model and further analyzed with regard to treatment, offender, and methodological characteristics to identify moderator variables. 

**Results: **
All eligible comparisons evaluated psychosocial treatment (mainly cognitive behavioral programs). None of the comparisons evaluating organic treatments fulfilled the eligibility criteria. The mean effect size for sexual recidivism was smaller than in our previous meta-analysis but still statistically significant (OR = 1.41, p &lt; .01). This equates to a difference in recidivism of 3.6 percentage points (10.1 % in treated vs. 13.7 % in untreated offenders) and a relative reduction in recidivism of 26.3 %. The significant overall effect was robust against outliers, but contained much heterogeneity. Methodological quality did not significantly influence effect sizes, but there were only a few randomized designs present. Cognitive-behavioral and multi-systemic treatment as well as studies with small samples, medium- to high-risk offenders, more individualized treatment, and good descriptive validity revealed better effects. In contrast to treatment in the community, treatment in prisons did not reveal a significant mean effect, but there were some prison studies with rather positive outcomes. 

**Conclusions: **
Although our findings are promising, the evidence basis for sex offender treatment is not yet satisfactory. More randomized trials and high-quality quasi-experiments are needed, particularly outside North America. In addition, there is a clear need of more differentiated process and outcome evaluations that address the questions of what works with whom, in what contexts, under what conditions, with regard to what outcomes, and also why. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Schmucker, Martin: martin.schmucker@fau.de; Losel, Friedrich: fal23@cam.ac.uk Schmucker, Martin: Institute of Psychology, Friedrich-Alexander University Erlangen-Nurnberg, Nagelsbachstr. 49c, Erlangen, Germany, D-91052, martin.schmucker@fau.de Schmucker, Martin: Institute of Psychology, Friedrich-Alexander University Erlangen-Nurnberg, Erlangen, Germany Losel, Friedrich: Institute of Psychology, Friedrich-Alexander University Erlangen-Nurnberg, Erlangen, Germany
AN  - 2015-38742-001
AU  - Schmucker,
AU  - M.
AU  - Losel,
AU  - F.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s11292-015-9241-z
DP  - Ovid Technologies
KW  - Evaluation, Meta-analysis, Recidivism, Sex offender treatment, Treatment efficacy
KW  - *Recidivism
KW  - *Sex Offenses
KW  - *Treatment
KW  - Criminal Rehabilitation &amp; Penology [3386]
KW  - Human Male Female Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older)
L1  - internal-pdf://3847207269/Schmucker-2015-The effects of sexual offender.pdf
LA  - English
M3  - Meta Analysis
PY  - 2015
SP  - 597-630
T2  - Journal of Experimental Criminology
TI  - The effects of sexual offender treatment on recidivism: An international meta-analysis of sound quality evaluations
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-38742-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs11292-015-9241-z&amp;issn=1573-3750&amp;isbn=&amp;volume=11&amp;issue=4&amp;spage=597&amp;pages=597-630&amp;date=2015&amp;title=Journal+of+Experimental+Criminology&amp;atitle=The+effects+of+sexual+offender+treatment+on+recidivism%3A+An+international+meta-analysis+of+sound+quality+evaluations.&amp;aulast=Schmucker&amp;pid=%3Cauthor%3ESchmucker%2C+Martin%3C%2Fauthor%3E%3CAN%3E2015-38742-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://download.springer.com/static/pdf/181/art%253A10.1007%252Fs11292-015-9241-z.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs11292-015-9241-z&amp;token2=exp=1489068686~acl=%2Fstatic%2Fpdf%2F181%2Fart%25253A10.1007%25252Fs11292-015-9241-z.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs11292-015-9241-z*~hmac=114d4bf5f6d4d64351fe433b26c024e265b452ac893332d1aea375c98303c32c
VL  - 11
ER  -
TY  - JOUR
AB  - This meta-analysis determined the effects of parent management training (PMT) on disruptive behaviors in children with a developmental disability.

Parent management training programs, based on behavioral theories of psychology, are commonly used in addressing disruptive behavior in children. 

Eleven studies met inclusion criteria with a total of 540 participants, with 275 in experimental groups and 265 in control groups. 

The effect of PMT on the disruptive behavior in children with a developmental disability was significant (g = 0.39). 

The moderator effects of type of PMT, delivery type and setting, and administrator level of education were also significant. 

The moderator effects of child age, and session number and duration were not significant in this meta-analysis. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Skotarczak, Laura: lms75@buffalo.edu Skotarczak, Laura, lms75@buffalo.edu Skotarczak, Laura: University at Buffalo- State University of New York, Buffalo, NY, US Lee, Gloria K.: Michigan State University, East Lansing, MI, US
AN  - 2015-07777-028
AU  - Skotarczak,
AU  - L.
AU  - Lee,
AU  - G.
AU  - K.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ridd.2014.12.004
DP  - Ovid Technologies
KW  - Meta-analysis, Parent management training, Parenting, Child behavior, Developmental disability
KW  - *Behavior Problems
KW  - *Developmental Disabilities
KW  - *Family Intervention
KW  - *Parent Training
KW  - Childhood Development
KW  - Community &amp; Social Services [3373]
KW  - Age Factors
KW  - Attention Deficit and Disruptive Behavior Disorders
KW  - Behavior Therapy
KW  - Child
KW  - Child, Preschool
KW  - Developmental Disabilities
KW  - Humans
KW  - Parenting
KW  - Parents
KW  - Treatment Outcome
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://0890617244/Skotarczak-2015-Effects of parent management t.pdf
LA  - English
M3  - Meta Analysis
PY  - 2015
SP  - 272-287
T2  - Research in Developmental Disabilities
TI  - Effects of parent management training programs on disruptive behavior for children with a developmental disability: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-07777-028http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.ridd.2014.12.004&amp;issn=0891-4222&amp;isbn=&amp;volume=38&amp;issue=&amp;spage=272&amp;pages=272-287&amp;date=2015&amp;title=Research+in+Developmental+Disabilities&amp;atitle=Effects+of+parent+management+training+programs+on+disruptive+behavior+for+children+with+a+developmental+disability%3A+A+meta-analysis.&amp;aulast=Skotarczak&amp;pid=%3Cauthor%3ESkotarczak%2C+Laura%3C%2Fauthor%3E%3CAN%3E2015-07777-028%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0891422214005095/1-s2.0-S0891422214005095-main.pdf?_tid=f878acca-04cf-11e7-8f12-00000aacb360&amp;acdnat=1489067873_8e13e99b63782bc14f7cbcd768448d8d
VL  - 38
ER  -
TY  - JOUR
AB  - Dental anxiety is one of the major problems affecting children, which impairs the rendering of dental care, leading to impaired quality of life. It often leads to occupational stress in dental personnel and conflict between parents/caregivers. The objective of this study was to conduct a systematic review and meta-analysis of randomized controlled trials done in children, to synthesize evidence of the effectiveness of atraumatic restorative treatment (ART) in reducing dental anxiety in children compared to conventional restorative treatments. The databases searched included PubMed, Google Scholar and The Cochrane Oral Health Group&#039;s Trials Register. Eligible studies reporting dental anxiety by a variety of psychometric scales were tabulated. The review was conducted and reported in accordance with the guidelines provided by the Cochrane Collaboration. Among 416 studies retrieved through literature search, six studies matched the inclusion criteria. Due to lack of data, only three studies were included for meta-analysis using RevMan software (Review Manager, Version 5.3;The Cochrane Collaboration, Copenhagen, 2014). The pooled meta-analysis data, (standardized mean difference - 2.12 [95% confidence interval: -4.52, 0.27]) failed to show any difference between ART group and the conventional treatment group. In conclusion, ART was not more beneficial in reducing dental anxiety among pediatric dental patients. The findings are relevant in the field of clinical practice in dentistry in the management of the anxious pediatric dental patient.
AN  - 26038668
AU  - Simon,
AU  - A.
AU  - K.
AU  - Bhumika,
AU  - T.
AU  - V.
AU  - Nair,
AU  - N.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4103/1305-7456.156841
L1  - internal-pdf://4001036566/Simon-2015-Does atraumatic restorative treatme.pdf
PY  - 2015
SP  - 304-9
TI  - Does atraumatic restorative treatment reduce dental anxiety in children? A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26038668
UR  - http://www.eurjdent.com/article.asp?issn=1305-7456;year=2015;volume=9;issue=2;spage=304;epage=309;aulast=Simon
VL  - 9
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To evaluate the evidence base relating to the effectiveness of parent-administered behavioral interventions for ADHD. 

**METHOD: **
A systematic review of randomized controlled trials or non-randomized but adequately controlled trials for children with ADHD or high levels of ADHD symptoms was carried out across multiple databases. For meta-analyses, the most proximal ratings of child symptoms were used as the primary outcome measure. 

**RESULTS: **
Eleven studies met inclusion criteria (603 children, age range = 33-144 months). Parenting interventions were associated with reduction in ADHD symptoms (Standardized Mean Difference [SMD] = 0.68; 95% confidence interval [CI] [0.32, 1.04]). There was no evidence of attenuation of effectiveness after excluding studies where medication was also used. Parenting interventions were also effective for comorbid conduct problems (SMD = 0.59; 95% CI [0.29, 0.90]) and parenting self-esteem (SMD = 0.93; 95% CI [0.48, 1.39]). 

**CONCLUSION: **
These findings support clinical practice guidelines and suggest that parenting interventions are effective. There is a need to ensure the availability of parenting interventions in community settings. 

Copyright &copy; 2014 SAGE Publications.
AD  - Coates, Janine. Division of Psychology, Nottingham Trent University, UK. Taylor, John A. NIHR Collaboration for Leadership in Applied Health Research and Care Nottinghamshire, Derbyshire and Lincolnshire. Sayal, Kapil. Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, UK kapil.sayal@nottingham.ac.uk.
AN  - 24915737
AU  - Coates,
AU  - J.
AU  - Taylor,
AU  - J.
AU  - A.
AU  - Sayal,
AU  - K.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1087054714535952
DP  - Ovid Technologies
J2  - J Atten Disord
KW  - Attention Deficit Disorder with Hyperactivity/px [Psychology]
KW  - *Attention Deficit Disorder with Hyperactivity/th [Therapy]
KW  - *Behavior Therapy/mt [Methods]
KW  - Child
KW  - Female
KW  - Humans
KW  - Infant
KW  - Male
KW  - Outcome Assessment (Health Care)
KW  - *Parenting
KW  - *Parents/ed [Education]
KW  - Parents/px [Psychology]
KW  - Self Concept
L1  - internal-pdf://1278783883/Coates-2015-Parenting Interventions for ADHD_.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Coates, Janine Taylor, John A Sayal, Kapil 1087054714535952
PY  - 2015
SP  - 831-43
T2  - Journal of Attention Disorders
TI  - Parenting Interventions for ADHD: A Systematic Literature Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24915737http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24915737&amp;id=doi:10.1177%2F1087054714535952&amp;issn=1087-0547&amp;isbn=&amp;volume=19&amp;issue=10&amp;spage=831&amp;pages=831-43&amp;date=2015&amp;title=Journal+of+Attention+Disorders&amp;atitle=Parenting+Interventions+for+ADHD%3A+A+Systematic+Literature+Review+and+Meta-Analysis.&amp;aulast=Coates&amp;pid=%3Cauthor%3ECoates+J%3C%2Fauthor%3E%3CAN%3E24915737%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 19
ER  -
TY  - JOUR
AB  - Children with autism spectrum disorders often exhibit co-occurring sensory processing problems and receive interventions that target self-regulation. 

In current practice, sensory interventions apply different theoretic constructs, focus on different goals, use a variety of sensory modalities, and involve markedly disparate procedures. Previous reviews examined the effects of sensory interventions without acknowledging these inconsistencies. 

This systematic review examined the research evidence (2000-2012) of two forms of sensory interventions, sensory integration therapy and sensory-based intervention, for children with autism spectrum disorders and concurrent sensory processing problems. 

A total of 19 studies were reviewed: 5 examined the effects of sensory integration therapy and 14 sensory-based intervention. The studies defined sensory integration therapies as clinic-based interventions that use sensory-rich, child-directed activities to improve a child&#039;s adaptive responses to sensory experiences. 

Two randomized controlled trials found positive effects for sensory integration therapy on child performance using Goal Attainment Scaling (effect sizes ranging from .72 to 1.62); other studies (Levels III-IV) found positive effects on reducing behaviors linked to sensory problems. Sensory-based interventions are characterized as classroom-based interventions that use single-sensory strategies, for example, weighted vests or therapy balls, to influence a child&#039;s state of arousal. 

Few positive effects were found in sensory-based intervention studies. Studies of sensory-based interventions suggest that they may not be effective; however, they did not follow recommended protocols or target sensory processing problems. 

Although small randomized controlled trials resulted in positive effects for sensory integration therapies, additional rigorous trials using manualized protocols for sensory integration therapy are needed to evaluate effects for children with autism spectrum disorders and sensory processing problems. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Case-Smith, Jane: jane.case-smith@osumc.edu Case-Smith, Jane: Division of Occupational Therapy, Ohio State University, 406 Atwell Hall, 435 West 10th Avenue, Columbus, OH, US, 43210, jane.case-smith@osumc.edu Case-Smith, Jane: Ohio State University, Columbus, OH, US Weaver, Lindy L.: Ohio State University, Columbus, OH, US Fristad, Mary A.: Ohio State University, Columbus, OH, US
AN  - 2015-04365-002
AU  - Case-Smith,
AU  - J.
AU  - Weaver,
AU  - L.
AU  - L.
AU  - Fristad,
AU  - M.
AU  - A.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1362361313517762
DP  - Ovid Technologies
KW  - sensory integration therapy, sensory processing, systematic review
KW  - *Autism Spectrum Disorders
KW  - *Intervention
KW  - *Self-Regulation
KW  - *Sensory Integration
KW  - Childhood Development
KW  - Developmental Disorders &amp; Autism [3250]
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Adolescent
KW  - Adult
KW  - Child
KW  - Child Development Disorders, Pervasive
KW  - Child, Preschool
KW  - Humans
KW  - Occupational Therapy
KW  - Sensation Disorders
KW  - Young Adult
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://1477159198/Case-2015-A systematic review of sensory proce.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2015
SP  - 133-148
T2  - Autism
TI  - A systematic review of sensory processing interventions for children with autism spectrum disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-04365-002http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1362361313517762&amp;issn=1362-3613&amp;isbn=&amp;volume=19&amp;issue=2&amp;spage=133&amp;pages=133-148&amp;date=2015&amp;title=Autism&amp;atitle=A+systematic+review+of+sensory+processing+interventions+for+children+with+autism+spectrum+disorders.&amp;aulast=Case-Smith&amp;pid=%3Cauthor%3ECase-Smith%2C+Jane%3C%2Fauthor%3E%3CAN%3E2015-04365-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 19
ER  -
TY  - JOUR
AB  - **Background:** 
Sexual and intimate partner violence (IPV) is a leading cause of disease burden, with alcohol use strongly related to these behaviors. Online interventions have been shown to be effective in reducing both alcohol use and some alcohol-related problems. These programs are widely available especially to university students, a particularly high-risk group for sexual or IPV. 

**Aim: **
We aimed to systematically review the evidence for the effectiveness of online alcohol interventions in reducing sexual violence or IPV. 

**Methods: **
We searched electronic databases (PsycInfo, Embase, Global Health, Medline, CINAHI, Pubmed, and ProQuest) and hand searched key reviews. 

**Results: **
From 569 titles, 23 were assessed in detail: five articles (four studies) fulfilled the inclusion criteria. All these studies were undertaken in the USA, with three recruiting college students (n. = 17,332), and one using an emergency department (n. = 262) sample of adolescents. We summarized the characteristics of the samples, the interventions and outcomes for alcohol use and sexual violence or IPV. Most interventions were unguided, with only one group receiving a guided intervention. Effect sizes, where they could be calculated, were small (Cohen&#039;s d&lt;. 0.2) or not significantly different to zero for alcohol, sexual violence or IPV outcomes. 

**Conclusions: **
Currently, there are insufficient data to evaluate the effectiveness of online alcohol interventions in reducing sexual or IPV. Given the prevalence of these behaviors and their association with alcohol use, this deficit requires urgent attention. 

Copyright &copy; 2015 The Authors.
AD  - (Tait, Lenton) National Drug Research Institute, Faculty of Health Sciences, Curtin University, Perth, WA 6008, Australia R.J. Tait, National Drug Research Institute, GPO Box U1987, Perth, WA 6845, Australia
AN  - 603243571
AU  - Tait,
AU  - R.
AU  - J.
AU  - Lenton,
AU  - S.
DA  - May 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.invent.2015.03.001
DP  - Ovid Technologies
KW  - Alcohol
KW  - Intimate partner violence
KW  - Online intervention
KW  - Sexual violence
KW  - Systematic review
KW  - alcoholism
KW  - bibliographic database
KW  - clinical assessment
KW  - clinical research
KW  - electronic medical record
KW  - evidence based practice
KW  - human
KW  - information processing
KW  - intervention study
KW  - online system
KW  - partner violence
KW  - prevalence
KW  - review
KW  - risk assessment
KW  - adolescent
KW  - alcohol consumption
KW  - college student
KW  - data base
KW  - effect size
KW  - Embase
KW  - emergency ward
KW  - health
KW  - high risk population
KW  - Medline
KW  - non implantable urine incontinence electrical stimulator
KW  - PsycINFO
KW  - university student
L1  - internal-pdf://1798033465/Tait-2015-Online alcohol interventions, sexual.pdf
LA  - English
M3  - Review
PY  - 2015
SP  - 152-160
T2  - Internet Interventions
TI  - Online alcohol interventions, sexual violence and intimate partner violence: A systematic review
UR  - http://www.journals.elsevier.com/internet-interventions/http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed17&amp;AN=603243571http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.invent.2015.03.001&amp;issn=2214-7829&amp;isbn=&amp;volume=2&amp;issue=2&amp;spage=152&amp;pages=152-160&amp;date=2015&amp;title=Internet+Interventions&amp;atitle=Online+alcohol+interventions%2C+sexual+violence+and+intimate+partner+violence%3A+A+systematic+review&amp;aulast=Tait&amp;pid=%3Cauthor%3ETait+R.J.%3C%2Fauthor%3E%3CAN%3E603243571%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S2214782915000123/1-s2.0-S2214782915000123-main.pdf?_tid=b0afbeb4-04d0-11e7-8b94-00000aacb360&amp;acdnat=1489068182_6ab279687faf5edf421aa31be81f8000
VL  - 2
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Disruptive behavior disorders are among the most common child and adolescent psychiatric disorders and associated with significant impairment. 

**OBJECTIVE: **
Systematically review studies of psychosocial interventions for children with disruptive behavior disorders.

**METHODS:** 
We searched Medline (via PubMed), Embase, and PsycINFO. Two reviewers assessed studies against predetermined inclusion criteria. Data were extracted by 1 team member and reviewed by a second. We categorized interventions as having only a child component, only a parent component, or as multicomponent interventions. 

**RESULTS: **
Sixty-six studies were included. Twenty-eight met criteria for inclusion in our meta-analysis. The effect size for the multicomponent interventions and interventions with only a parent component had the same estimated value, with a median of -1.2 SD reduction in outcome score (95% credible interval, -1.6 to -0.9). The estimate for interventions with only a child component was -1.0 SD (95% credible interval, -1.6 to -0.4). 

**LIMITATIONS: **
Methodologic limitations of the available evidence (eg, inconsistent or incomplete outcome reporting, inadequate blinding or allocation concealment) may compromise the strength of the evidence. Population and intervention inclusion criteria and selected outcome measures eligible for inclusion in the meta-analysis may limit applicability of the results. 

**CONCLUSIONS: **
The 3 intervention categories were more effective than the control conditions. Interventions with a parent component, either alone or in combination with other components, were likely to have the largest effect. Although additional research is needed in the community setting, our findings suggest that the parent component is critical to successful intervention. 

Copyright &copy; 2015 by the American Academy of Pediatrics.
AD  - Epstein, Richard A. Institute for Medicine and Public Health, Evidence-Based Practice Center, and Division of Child and Adolescent Psychiatry, Department of Psychiatry, repstein@chapinhall.org. Fonnesbeck, Christopher. Institute for Medicine and Public Health, Evidence-Based Practice Center, and Departments of Biostatistics, and. Potter, Shannon. Institute for Medicine and Public Health, Evidence-Based Practice Center, and. Rizzone, Katherine H. Department of Sports Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; McPheeters, Melissa. Institute for Medicine and Public Health, Evidence-Based Practice Center, and Health Policy, Vanderbilt University School of Medicine, Nashville, Tennessee.
AN  - 26482672
AU  - Epstein,
AU  - R.
AU  - A.
AU  - Fonnesbeck,
AU  - C.
AU  - Potter,
AU  - S.
AU  - Rizzone,
AU  - K.
AU  - H.
AU  - McPheeters,
AU  - M.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2015-2577
DP  - Ovid Technologies
J2  - Pediatrics
KW  - Adolescent
KW  - Child
KW  - *Child Behavior Disorders/px [Psychology]
KW  - *Child Behavior Disorders/th [Therapy]
KW  - Humans
KW  - Parents
KW  - *Problem Behavior/px [Psychology]
KW  - Psychotherapy/mt [Methods]
KW  - Social Support
L1  - internal-pdf://3056784453/Epstein-2015-Psychosocial Interventions for Ch.pdf
LA  - English
M3  - Meta-Analysis Research Support, U.S. Gov&#039;t, P.H.S. Review
N1  - Epstein, Richard A Fonnesbeck, Christopher Potter, Shannon Rizzone, Katherine H McPheeters, Melissa peds.2015-2577
PY  - 2015
SP  - 947-60
T2  - Pediatrics
TI  - Psychosocial Interventions for Child Disruptive Behaviors: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26482672http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26482672&amp;id=doi:10.1542%2Fpeds.2015-2577&amp;issn=0031-4005&amp;isbn=&amp;volume=136&amp;issue=5&amp;spage=947&amp;pages=947-60&amp;date=2015&amp;title=Pediatrics&amp;atitle=Psychosocial+Interventions+for+Child+Disruptive+Behaviors%3A+A+Meta-analysis.&amp;aulast=Epstein&amp;pid=%3Cauthor%3EEpstein+RA%3C%2Fauthor%3E%3CAN%3E26482672%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://pediatrics.aappublications.org/content/pediatrics/136/5/947.full.pdf
VL  - 136
ER  -
TY  - JOUR
AB  - This meta-analysis synthesizes studies of brief interventions (BIs) that targeted alcohol consumption and reported both alcohol and tobacco outcomes. It examines whether BIs reduce alcohol and tobacco use for adolescents and young adults among interventions that (1) directly targeted tobacco and alcohol use, or (2) did not target tobacco use but measured it as a secondary outcome. 

Multiple databases and grey literature sources were searched (1980-2012) resulting in the identification of 18 randomized or controlled quasi-experimental studies (5949 participants). 

Analyses were conducted using random effects inverse-variance weighted three-level models. BIs were associated with a significant reduction in alcohol consumption relative to control groups [g = 0.11, 95 % CI (0.04, 0.17)] but not with a significant decrease in tobacco use [g = 0.07, 95 % CI (-0.01, 0.16)]. 

Directly addressing tobacco was not a significant moderator affecting tobacco use outcomes. Post-hoc exploratory analysis revealed potential questions to address with future research.
AD  - Hennessy, Emily A. Department of Human and Organizational Development, Peabody College, Vanderbilt University, Nashville, TN, USA. Emily.a.hennessy@vanderbilt.edu. Tanner-Smith, Emily E. Department of Human and Organizational Development, Peabody College, Vanderbilt University, Nashville, TN, USA. Tanner-Smith, Emily E. Peabody Research Institute, Vanderbilt University, Nashville, TN, USA. Steinka-Fry, Katarzyna T. Peabody Research Institute, Vanderbilt University, Nashville, TN, USA.
AN  - 26130030
AU  - Hennessy,
AU  - E.
AU  - A.
AU  - Tanner-Smith,
AU  - E.
AU  - E.
AU  - Steinka-Fry,
AU  - K.
AU  - T.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10865-015-9653-2
DP  - Ovid Technologies
J2  - J Behav Med
KW  - Adolescent
KW  - Alcohol Drinking/pc [Prevention &amp; Control]
KW  - *Alcohol Drinking/th [Therapy]
KW  - Databases, Factual
KW  - Humans
KW  - *Psychotherapy, Brief
KW  - Tobacco Use/pc [Prevention &amp; Control]
KW  - *Tobacco Use/th [Therapy]
KW  - Young Adult
L1  - internal-pdf://2680684130/Hennessy-2015-Do brief alcohol interventions r.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural Review
N1  - Hennessy, Emily A Tanner-Smith, Emily E Steinka-Fry, Katarzyna T 10.1007/s10865-015-9653-2
PY  - 2015
SP  - 899-911
T2  - Journal of Behavioral Medicine
TI  - Do brief alcohol interventions reduce tobacco use among adolescents and young adults? A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26130030http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26130030&amp;id=doi:10.1007%2Fs10865-015-9653-2&amp;issn=0160-7715&amp;isbn=&amp;volume=38&amp;issue=6&amp;spage=899&amp;pages=899-911&amp;date=2015&amp;title=Journal+of+Behavioral+Medicine&amp;atitle=Do+brief+alcohol+interventions+reduce+tobacco+use+among+adolescents+and+young+adults%3F+A+systematic+review+and+meta-analysis.&amp;aulast=Hennessy&amp;pid=%3Cauthor%3EHennessy+EA%3C%2Fauthor%3E%3CAN%3E26130030%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636017/pdf/nihms733090.pdf
VL  - 38
ER  -
TY  - JOUR
AB  - **Objective **
The aim of this systematic review and meta-analysis was to examine the evidence for the effectiveness of exercise interventions on attention deficit hyperactivity disorder (ADHD)-related symptoms such as inattention, hyperactivity/impulsivity, anxiety and cognitive functions in children and adolescents. 

**Method **
Five databases covering the period up to November 2014 (PubMed, Scopus, EMBASE, EBSCO [E-journal, CINAHL, SportDiscus] and The Cochrane Library) were searched. Methodological quality was assessed using the Cochrane tool of bias. Standardized mean differences (SMD) and 95% confidence intervals were calculated, and the heterogeneity of the studies was estimated using Cochran&#039;s Q-statistic. 

**Results **
Eight randomized controlled trials (n = 249) satisfied the inclusion criteria. The studies were grouped according to the intervention programme: aerobic and yoga exercise. The meta-analysis suggests that aerobic exercise had a moderate to large effect on core symptoms such as attention (SMD = 0.84), hyperactivity (SMD = 0.56) and impulsivity (SMD = 0.56) and related symptoms such as anxiety (SMD = 0.66), executive function (SMD = 0.58) and social disorders (SMD = 0.59) in children with ADHD. Yoga exercise suggests an improvement in the core symptoms of ADHD. 

**Conclusions **
The main cumulative evidence indicates that short-term aerobic exercise, based on several aerobic intervention formats, seems to be effective for mitigating symptoms such as attention, hyperactivity, impulsivity, anxiety, executive function and social disorders in children with ADHD.
AD  - [Cerrillo-Urbina, A. J.; Sanchez-Lopez, M.; Pardo-Guijarro, M. J.; Martinez-Vizcaino, V.] Univ Castilla La Mancha, Social &amp; Hlth Care Res Ctr, Cuenca 16071, Spain. [Garcia-Hermoso, A.] Univ Autonoma Chile, Talca, Chile. [Sanchez-Lopez, M.; Pardo-Guijarro, M. J.] Univ Castilla La Mancha, Fac Educ, E-13071 Ciudad Real, Spain. [Santos Gomez, J. L.] Hosp Virgen La Luz, Cuenca, Spain. Martinez-Vizcaino, V (reprint author), Univ Castilla La Mancha, Ctr Estudios Sociosanitarios, Edificio Melchor Cano,Santa Teresa,Jornet S-N, Cuenca 16071, Spain. Vicente.Martinez@uclm.es
AN  - WOS:000367928800002
AU  - Cerrillo-Urbina,
AU  - A.
AU  - J.
AU  - Garcia-Hermoso,
AU  - A.
AU  - Sanchez-Lopez,
AU  - M.
AU  - Pardo-Guijarro,
AU  - M.
AU  - J.
AU  - Gomez,
AU  - J.
AU  - L.
AU  - S.
AU  - Martinez-Vizcaino,
AU  - V.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/cch.12255
J2  - Child Care Health Dev.
KW  - attention deficit hyperactivity disorder
KW  - children
KW  - cognitive function
KW  - exercise
KW  - meta-analysis
KW  - deficit/hyperactivity disorder
KW  - adhd
KW  - interventions
KW  - symptoms
KW  - prevalence
KW  - diagnosis
KW  - therapy
KW  - update
KW  - brain
KW  - risk
KW  - Psychology
KW  - Pediatrics
L1  - internal-pdf://0770681353/Cerrillo-2015-The effects of physical exercise.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DA6PZ Times Cited: 2 Cited Reference Count: 56 Cerrillo-Urbina, A. J. Garcia-Hermoso, A. Sanchez-Lopez, M. Pardo-Guijarro, M. J. Santos Gomez, J. L. Martinez-Vizcaino, V. Meijer, Anna/K-5118-2016; Cerrillo Urbina, Alberto Jose/0000-0001-5854-069X; MARTINEZ VIZCAINO, VICENTE/0000-0001-6121-7893; Sanchez Lopez, Mairena/0000-0002-0217-0623; Garcia-Hermoso, Antonio/0000-0002-1397-7182 2 9 36 Wiley-blackwell Hoboken 1365-2214
PY  - 2015
SP  - 779-788
T2  - Child Care Health and Development
TI  - The effects of physical exercise in children with attention deficit hyperactivity disorder: a systematic review and meta-analysis of randomized control trials
UR  - &lt;Go to ISI&gt;://WOS:000367928800002
UR  - http://onlinelibrary.wiley.com/store/10.1111/cch.12255/asset/cch12255.pdf?v=1&amp;t=j02df3o8&amp;s=edd9fda0105a17c9e3d70ea17b78655400ba310f
VL  - 41
ER  -
TY  - JOUR
AB  - **Background **
Many common disorders across the lifespan feature impaired working memory (WM). Reported benefits of aWM training program include improving inattention in daily life, but this has not been evaluated in a meta-analysis. This study aimed to evaluate whether one WM training method has benefits for inattention in daily life by conducting a systematic review and meta-analysis. 

**Methods **
We searched Medline and PsycINFO, relevant journals and contacted authors for studies with an intervention and control group reporting post-training estimates of inattention in daily life. To reduce the influence of differentWM training methods on the findings, the review was restricted to trials evaluating the Cogmed method. A meta-analysis calculated the pooled standardised difference in means (SMD) between intervention and control groups. 

**Results **
A total of 622 studies were identified and 12 studies with 13 group comparisons met inclusion criteria. The meta-analysis showed a significant training effect on inattention in daily life, SMD=-0.47, 95% CI -0.65, -0.29, p&lt;.00001. Subgroup analyses showed this significant effect was observed in groups of children and adults as well as users with and without ADHD, and in studies using control groups that were active and non-adaptive, wait-list and passive as well as studies using specific or general measures. Seven of the studies reported follow-up assessment and a meta-analysis showed persisting training benefits for inattention in daily life, SMD=-0.33, 95% CI -0.57 -0.09, p =.006. Additional meta-analyses confirmed improvements after training on visuospatial WM, SMD=0.66, 95% CI 0.43, 0.89, p&lt;.00001, and verbal WM tasks, SMD=0.40, 95% CI 0.18, 0.62, p = .0004. 

**Conclusions **
Benefits of aWM training program generalise to improvements in everyday functioning. Initial evidence shows that the Cogmed method has significant benefits for inattention in daily life with a clinically relevant effect size.
AD  - [Spencer-Smith, Megan; Klingberg, Torkel] Karolinska Inst, Dept Neurosci, Stockholm, Sweden. [Spencer-Smith, Megan] Monash Univ, Sch Psychol Sci, Melbourne, Vic 3004, Australia. Spencer-Smith, M (reprint author), Karolinska Inst, Dept Neurosci, Stockholm, Sweden. megan.spencer-smith@mcri.edu.au
AN  - WOS:000352084200089
AU  - Spencer-Smith,
AU  - M.
AU  - Klingberg,
AU  - T.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1371/journal.pone.0119522
J2  - PLoS One
KW  - attention-deficit/hyperactivity disorder
KW  - controlled-trial
KW  - cognitive
KW  - deficits
KW  - fluid intelligence
KW  - brain-injury
KW  - children
KW  - adhd
KW  - adolescents
KW  - achievement
KW  - preschoolers
KW  - Science &amp; Technology - Other Topics
L1  - internal-pdf://0702202962/Spencer-2015-Benefits of a Working Memory Trai.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CE8IA Times Cited: 16 Cited Reference Count: 60 Spencer-Smith, Megan Klingberg, Torkel Spencer-Smith, Megan/0000-0002-1047-0829 16 7 61 Public library science San francisco
PY  - 2015
SP  - 18
T2  - Plos One
TI  - Benefits of a Working Memory Training Program for Inattention in Daily Life: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000352084200089
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0119522&amp;type=printable
VL  - 10
ER  -
TY  - JOUR
AB  - This meta-analysis evaluated the effects of the expressive writing intervention (EW; Pennebaker &amp; Beall, 1986) among adolescents. Twenty-one independent studies that assessed the efficacy of expressive writing on youth samples aged 10-18. years were collected and analyzed. 

Results indicated an overall mean g-effect size that was positive in direction but relatively small (0.127), as well as significant g-effect sizes ranging from 0.107 to 0.246 for the outcome domains of emotional distress, Problem Behavior, Social Adjustment, and School Participation. 

Few significant effects were found within specific outcome domains for putative moderator variables that included characteristics of the participants, intervention instructions, or research design. Studies involving adolescents with high levels of emotional problems at baseline reported larger effects on school performance. 

Studies that implemented a higher dosage intervention (i.e., greater number and, to some extent, greater spacing of sessions) reported larger effects on somatic complaints. 

Overall, the findings suggest that expressive writing tends to produce small yet significant improvements on adolescents&#039; well-being. The findings highlight the importance of modifying the traditional expressive writing protocol to enhance its efficacy and reduce potential detrimental effects. 

At this stage of research the evidence on expressive writing as a viable intervention for adolescents is promising but not decisive.
AD  - (Travagin, Margola) Catholic University of Milan, Italy (Revenson) Hunter College and The Graduate Center, City University, NY, United States G. Travagin, Faculty of Psychology, Catholic University of Milan, Largo A. Gemelli 1, Milan, MI 20123, Italy
AN  - 2015760429
AU  - Travagin,
AU  - G.
AU  - Margola,
AU  - D.
AU  - Revenson,
AU  - T.
AU  - A.
DA  - March 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2015.01.003
DP  - Ovid Technologies
KW  - Adolescence Expressive Writing (EW) Meta-analysis Self-regulation processes Written emotional disclosure academic achievement adolescent adolescent health alcoholism asthma depression emotional stress expressive writing human juvenile meta analysis pare
LA  - English
M3  - Review
PY  - 2015
SP  - 42-55
T2  - Clinical Psychology Review
TI  - How effective are expressive writing interventions for adolescents? A meta-analytic review
UR  - www.elsevier.com/locate/clinpsychrev http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed13&amp;AN=2015760429 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.cpr.2015.01.003&amp;issn=0272-7358&amp;isbn=&amp;volume=36&amp;issue=&amp;spage=42&amp;pages=42-55&amp;date=2015&amp;title=Clinical+Psychology+Review&amp;atitle=How+effective+are+expressive+writing+interventions+for+adolescents%3F+A+meta-analytic+review&amp;aulast=Travagin&amp;pid=%3Cauthor%3ETravagin+G.%3C%2Fauthor%3E%3CAN%3E2015760429%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735815000161/1-s2.0-S0272735815000161-main.pdf?_tid=82539f4a-1972-11e5-bfa3-00000aab0f02&amp;acdnat=1435041710_8d954d2c9e1b003d6fafcd3bd74027ee
VL  - 36
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
This systematic review evaluated the effectiveness of psychological interventions for reducing vaccination pain and related outcomes in children and adolescents. 

**DESIGN/METHODS: **
Database searches identified relevant randomized and quasi-randomized controlled trials. Data were extracted and pooled using established methods. Pain, fear, and distress were considered critically important outcomes. 

**RESULTS: **
Twenty-two studies were included; 2 included adolescents. Findings showed no benefit of false suggestion (n=240) for pain (standardized mean difference [SMD] -0.21 [-0.47, 0.05]) or distress (SMD -0.28 [-0.59, 0.11]), or for use of repeated reassurance (n=82) for pain (SMD -0.18 [-0.92, 0.56]), fear (SMD -0.18 [-0.71, 0.36]), or distress (SMD 0.10 [-0.33, 0.54]). Verbal distraction (n=46) showed reduced distress (SMD -1.22 [-1.87, -0.58]), but not reduced pain (SMD -0.27 [-1.02, 0.47]). Similarly, video distraction (n=328) showed reduced distress (SMD -0.58 [-0.82, -0.34]), but not reduced pain (SMD -0.88 [-1.78, 0.02]) or fear (SMD 0.08 [-0.25, 0.41]). Music distraction demonstrated reduced pain when used with children (n=417) (SMD -0.45 [-0.71, -0.18]), but not with adolescents (n=118) (SMD -0.04 [-0.42, 0.34]). Breathing with a toy (n=368) showed benefit for pain (SMD -0.49 [-0.85, -0.13]), but not fear (SMD -0.60 [-1.22, 0.02]); whereas breathing without a toy (n=136) showed no benefit for pain (SMD -0.27 [-0.61, 0.07]) or fear (SMD -0.36 [-0.86, 0.15]). There was no benefit for a breathing intervention (cough) in children and adolescents (n=136) for pain (SMD -0.17 [-0.41, 0.07]). 

**CONCLUSIONS: **
Psychological interventions with some evidence of benefit in children include: verbal distraction, video distraction, music distraction, and breathing with a toy.
AD  - Birnie, Kathryn A. Departments of *Psychology and Neuroscience ++Pediatrics, Dalhousie University +Centre for Pediatric Pain Research, IWK Health Centre, Halifax, NS Leslie Dan Faculty of Pharmacy, University of Toronto The Hospital for Sick Children ++++York University Mount Sinai Hospital Faculty of Medicine, University of Toronto, Toronto PDepartment of Psychology, University of Guelph, Guelph #Children&#039;s Health Research Institute **Department of Paediatrics, Western University, London, ON ++Department of Psychology, University of Calgary, AB, Canada.
AN  - 26348163
AU  - Birnie,
AU  - K.
AU  - A.
AU  - Chambers,
AU  - C.
AU  - T.
AU  - Taddio,
AU  - A.
AU  - McMurtry,
AU  - C.
AU  - M.
AU  - Noel,
AU  - M.
AU  - Pillai
AU  - Riddell,
AU  - R.
AU  - Shah,
AU  - V.
AU  - HELPinKids
AU  - &amp;
AU  - Adults
AU  - Team
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/AJP.0000000000000265
DP  - Ovid Technologies
J2  - Clin J Pain
KW  - Adolescent
KW  - Child
KW  - Databases, Bibliographic/sn [Statistics &amp; Numerical Data]
KW  - Humans
KW  - *Injections/ae [Adverse Effects]
KW  - *Pain/et [Etiology]
KW  - *Pain/rh [Rehabilitation]
KW  - *Psychotherapy/mt [Methods]
KW  - Randomized Controlled Trials as Topic
KW  - *Vaccination/ae [Adverse Effects]
L1  - internal-pdf://3088423622/Birnie-2015-Psychological Interventions for Va.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Birnie, Kathryn A Chambers, Christine T Taddio, Anna McMurtry, C Meghan Noel, Melanie Pillai Riddell, Rebecca Shah, Vibhuti HELPinKids&amp;Adults Team MacDonald NE Rogers J Bucci L Lang E Mousmanis P Halperin SA Bowles S Halpert C Ipp M Rieder M Robson K Asmundson GJ Uleryk E Antony M Alexander D Appleton M Dubey V Hanrahan A Lockett D Scott J Votta Bleeker E 00002508-201510001-00008
PY  - 2015
SP  - S72-89
T2  - Clinical Journal of Pain
TI  - Psychological Interventions for Vaccine Injections in Children and Adolescents: Systematic Review of Randomized and Quasi-Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26348163http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26348163&amp;id=doi:10.1097%2FAJP.0000000000000265&amp;issn=0749-8047&amp;isbn=&amp;volume=31&amp;issue=10&amp;spage=S72&amp;pages=S72-89&amp;date=2015&amp;title=Clinical+Journal+of+Pain&amp;atitle=Psychological+Interventions+for+Vaccine+Injections+in+Children+and+Adolescents%3A+Systematic+Review+of+Randomized+and+Quasi-Randomized+Controlled+Trials.&amp;aulast=Birnie&amp;pid=%3Cauthor%3EBirnie+KA%3C%2Fauthor%3E%3CAN%3E26348163%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900411/pdf/ajp-31-s72.pdf
VL  - 31
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
Youth suicide is highly related to mental disorders. While communities and schools are marketed to with a plethora of suicide prevention programs, they often lack the capacity to choose evidence-based programs. 

**METHODS: **
We conducted a systematic review of two youth suicide prevention programs to help determine if the quality of evidence available justifies their wide spread dissemination. We searched Medline, PsycINFO, EMBASE, CINAHL, the Cochrane Library, Campbell Collaboration SPECTR database, SocIndex, Sociological Abstracts, Social Services Abstracts, ERIC, Social Work Abstracts, Research Library, and Web of Science, for relevant studies. We included studies/systematic reviews/meta-analysis that evaluated the effectiveness, cost-effectiveness, and/or safety of Signs of Suicide (SOS) and Yellow Ribbon (YR) suicide prevention programs that target adolescents. We applied the Office of Justice Program What Works Repository (OJP-R) to evaluate the quality of the included studies as effective, effective with reservation, promising, inconclusive evidence, insufficient evidence, and ineffective. Two SOS studies were ranked as &quot;inconclusive evidence&quot; based on the OJP-R. One SOS study was ranked as having &quot;insufficient evidence&quot; on OJP-R. The YR study was ranked as &quot;ineffective&quot; using OJP-R. We only included studies in peer-reviewed journals in English and therefore may have missed reports in grey literature or non-English publications. 

**RESULTS: **
We cannot recommend that schools and communities implement either the SOS or YR suicide prevention programs. Purchasers of these programs should be aware that there is no evidence that their use prevents suicide. 

**CONCLUSIONS: **
Academics and organizations should not overstate the positive impacts of suicide prevention interventions when the evidence is lacking.
AD  - Wei, Yifeng. IWK Health Centre, Halifax, Nova Scotia. Kutcher, Stan. Department of Psychiatry and Sun Life Financial Chair in Adolescent Mental Health, Dalhousie University and IWK Health Centre, Halifax, Nova Scotia. LeBlanc, John C. Department of Pediatrics, Psychiatry, Epidemiology and Community Health, Dalhousie University, Halifax, Nova Scotia.
AN  - 26336375
AU  - Wei,
AU  - Y.
AU  - Kutcher,
AU  - S.
AU  - LeBlanc,
AU  - J.
AU  - C.
DA  - Winter
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pubmed/26336375
DP  - Ovid Technologies
J2  - J Can Acad Child Adolesc Psychiatry
L1  - internal-pdf://2764958250/Wei-2015-Hot Idea or Hot Air_ A Systematic Rev.pdf
LA  - English
N1  - Wei, Yifeng Kutcher, Stan LeBlanc, John C
PY  - 2015
SP  - 5-16
T2  - Journal of the Canadian Academy of Child &amp; Adolescent Psychiatry = Journal de l.Acade.mie canadienne de psychiatrie de l.enfant et de l.adolescent
TI  - Hot Idea or Hot Air: A Systematic Review of Evidence for Two Widely Marketed Youth Suicide Prevention Programs and Recommendations for Implementation
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26336375http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26336375&amp;id=doi:&amp;issn=1719-8429&amp;isbn=&amp;volume=24&amp;issue=1&amp;spage=5&amp;pages=5-16&amp;date=2015&amp;title=Journal+of+the+Canadian+Academy+of+Child+%26+Adolescent+Psychiatry+%3D+Journal+de+l.Acade.mie+canadienne+de+psychiatrie+de+l.enfant+et+de+l.adolescent&amp;atitle=Hot+Idea+or+Hot+Air%3A+A+Systematic+Review+of+Evidence+for+Two+Widely+Marketed+Youth+Suicide+Prevention+Programs+and+Recommendations+for+Implementation.&amp;aulast=Wei&amp;pid=%3Cauthor%3EWei+Y%3C%2Fauthor%3E%3CAN%3E26336375%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357329/pdf/ccap24_p0005.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Previous studies have shown an unmet need in the treatment of eating disorders. In the last decade, interest in technology-based interventions (TBIs) (including computer- and Internet-based interventions [CBIs] or mobile interventions) for providing evidence-based therapies to individuals with different mental disorders has increased. 

**OBJECTIVE: **
The aim of this review was to systematically evaluate the potential of TBIs in the field of eating disorders, namely for anorexia nervosa (AN) and bulimia nervosa (BN), for both prevention and treatment, and also for carers of eating disorder patients. 

**METHODS: **
A systematic literature search was conducted using Medline and PsycINFO. Bibliographies of retrieved articles were also reviewed without date or study type restrictions. 

**RESULTS: **
Forty studies resulting in 45 publications reporting outcomes fulfilled the inclusion criteria: 22 randomized controlled trials, 2 controlled studies, and 16 uncontrolled studies. In total, 3646 patients were included. Overall, the studies provided evidence for the efficacy of guided CBIs, especially for BN patients and for compliant patients. Furthermore, videoconferencing also appeared to be a promising approach. Evaluation results of Internet-based prevention of eating disorders and Internet-based programs for carers of eating disorder patients were also encouraging. Finally, there was preliminary evidence for the efficacy of mobile interventions.

**CONCLUSIONS: **
TBIs may be an additional way of delivering evidence-based treatments to eating disorder patients and their use is likely to increase in the near future. TBIs may also be considered for the prevention of eating disorders and to support carers of eating disorder patients. Areas of future research and important issues such as guidance, therapeutic alliance, and dissemination are discussed.
AD  - Schlegl, Sandra. Department of Psychiatry and Psychotherapy, University of Munich, Munchen, Germany. sandra.schlegl@med.uni-muenchen.de.
AN  - 25840591
AU  - Schlegl,
AU  - S.
AU  - Burger,
AU  - C.
AU  - Schmidt,
AU  - L.
AU  - Herbst,
AU  - N.
AU  - Voderholzer,
AU  - U.
DA  - Mar 31
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2196/jmir.3554
DP  - Ovid Technologies
J2  - J Med Internet Res
KW  - Adolescent
KW  - Adult
KW  - Anorexia/px [Psychology]
KW  - *Anorexia/th [Therapy]
KW  - *Biomedical Technology/mt [Methods]
KW  - Bulimia Nervosa/px [Psychology]
KW  - *Bulimia Nervosa/th [Therapy]
KW  - Humans
KW  - *Internet
KW  - *Psychotherapy/mt [Methods]
KW  - Young Adult
L1  - internal-pdf://3790386854/fc-xsltGalley-3554-56006-24-PB.pdf
LA  - English
M3  - Review
N1  - Schlegl, Sandra Burger, Carolina Schmidt, Luise Herbst, Nirmal Voderholzer, Ulrich v17i3e85
PY  - 2015
SP  - e85
T2  - Journal of Medical Internet Research
TI  - The potential of technology-based psychological interventions for anorexia and bulimia nervosa: a systematic review and recommendations for future research
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25840591http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25840591&amp;id=doi:10.2196%2Fjmir.3554&amp;issn=1438-8871&amp;isbn=&amp;volume=17&amp;issue=3&amp;spage=e85&amp;pages=e85&amp;date=2015&amp;title=Journal+of+Medical+Internet+Research&amp;atitle=The+potential+of+technology-based+psychological+interventions+for+anorexia+and+bulimia+nervosa%3A+a+systematic+review+and+recommendations+for+future+research.&amp;aulast=Schlegl&amp;pid=%3Cauthor%3ESchlegl+S%3C%2Fauthor%3E%3CAN%3E25840591%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 17
ER  -
TY  - JOUR
AB  - **Background**
Despite accumulating research and bold claims about the efficacy of cognitive bias modification (CBM) for young populations, no meta-analysis has attempted to synthesize the research literature so far. We examined whether there was empirical evidence for the clinical efficacy of CBM interventions in youths, while also considering the methodological quality of this evidence. 

**Methods**
Studies were identified through systematic searches in bibliographical databases (PubMed, PsychInfo, Cochrane Library and EMBASE to June 2014). We included randomized controlled trials of CBM interventions, and considered both clinical outcomes and targeted biases. We examined the quality of the trials, as well as potential publication bias and possible moderators. 

**Results**
We identified 23 trials that reported on four types of outcomes: mental health, anxiety, depression and bias. Effect sizes were small and nonsignificant for all symptom outcomes considered. We found a moderate significant effect size for bias outcomes (Hedges&#039; g of 0.53), with significant heterogeneity. There were no differences between types of CBM interventions, or between one versus multiple-session applications. A small but significant effect size for mental health problems arose when the intervention was delivered in schools. The quality of almost all of the included studies was suboptimal and the vast majority did not include information needed for allowing quality assessment. 

**Conclusions**
We conducted the first meta-analysis of CBM interventions for childrenand adolescents and found no effects for mental health outcomes, but we did find moderate and significant effects on the targeted biases. Our results cast serious doubts on CBM interventions having any clinical utility for nonadult populations. Demand characteristics might play an important part in CBM research.
AD  - [Cristea, Ioana A.; Mogoase, Cristina; David, Daniel] Univ Babes Bolyai, Dept Clin Psychol &amp; Psychotherapy, Cluj Napoca 400015, Romania. [Cristea, Ioana A.] Univ Pisa, Dept Surg Med Mol &amp; Crit Pathol, Clin Psychol Branch, Pisa, Italy. [David, Daniel] Icahn Sch Med Mt Sinai, Dept Oncol Sci, New York, NY 10029 USA. [Cuijpers, Pim] Vrije Univ Amsterdam, Dept Clin Psychol, Amsterdam, Netherlands. [Cuijpers, Pim] Vrije Univ Amsterdam, EMGO Inst Hlth &amp; Care Res, Amsterdam, Netherlands. [Cuijpers, Pim] Vrije Univ Amsterdam, Med Ctr, Amsterdam, Netherlands. Cristea, IA (reprint author), Univ Babes Bolyai, Dept Clin Psychol &amp; Psychotherapy, Republ St 37, Cluj Napoca 400015, Romania. ioana.cristea@ubbcluj.ro
AN  - WOS:000355987600002
AU  - Cristea,
AU  - I.
AU  - A.
AU  - Mogoase,
AU  - C.
AU  - David,
AU  - D.
AU  - Cuijpers,
AU  - P.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jcpp.12383
J2  - J. Child Psychol. Psychiatry
KW  - Cognitive bias modification
KW  - meta-analysis
KW  - RCT interventions
KW  - clinical
KW  - efficacy
KW  - mental health
KW  - children
KW  - adolescents
KW  - randomized controlled-trial
KW  - attention bias
KW  - emotional disorders
KW  - anxiety disorders
KW  - pediatric anxiety
KW  - animal fear
KW  - vulnerability
KW  - metaanalyses
KW  - consequences
KW  - depression
KW  - Psychology
KW  - Psychiatry
L1  - internal-pdf://1225112117/Cristea-2015-Practitioner Review_ Cognitive bi.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CK1SM Times Cited: 12 Cited Reference Count: 55 Cristea, Ioana A. Mogoase, Cristina David, Daniel Cuijpers, Pim Cristea, Ioana/E-7490-2011 Cristea, Ioana/0000-0002-9854-7076 Romanian Executive Unit for Financing Education Higher Research, Development and Innovation (UEFISCDI) via the &#039;Effectiveness of an empirically based web platform for anxiety in youths&#039; grant [PN-II-PT-PCCA-2011-3.1-1500, 81/2012] C.M. was supported by the Romanian Executive Unit for Financing Education Higher Research, Development and Innovation (UEFISCDI) via the &#039;Effectiveness of an empirically based web platform for anxiety in youths&#039; grant (PN-II-PT-PCCA-2011-3.1-1500, 81/2012). No additional third-party study support was received for this study. The authors have declared that they have no competing or potential conflicts of interest to disclose. 13 5 33 Wiley-blackwell Hoboken 1469-7610
PY  - 2015
SP  - 723-734
T2  - Journal of Child Psychology and Psychiatry
TI  - Practitioner Review: Cognitive bias modification for mental health problems in children and adolescents: ameta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000355987600002
UR  - http://onlinelibrary.wiley.com/store/10.1111/jcpp.12383/asset/jcpp12383.pdf?v=1&amp;t=j02dnkzp&amp;s=d5622755a052d2734df29e941d4e708b3bf54a2f
VL  - 56
ER  -
TY  - JOUR
AB  - **CONTEXT: **
Low-income and minority status in the United States are associated with poor educational outcomes, which, in turn, reduce the long-term health benefits of education. 

**OBJECTIVE: **
This systematic review assessed the extent to which out-of-school-time academic (OSTA) programs for at-risk students, most of whom are from low-income and racial/ethnic minority families, can improve academic achievement. Because most OSTA programs serve low-income and ethnic/racial minority students, programs may improve health equity. 

**DESIGN: **
Methods of the Guide to Community Preventive Services were used. An existing systematic review assessing the effects of OSTA programs on academic outcomes (Lauer et al 2006; search period 1985-2003) was supplemented with a Community Guide update (search period 2003-2011). 

**MAIN OUTCOME MEASURE: **
Standardized mean difference. 

**RESULTS: **
Thirty-two studies from the existing review and 25 studies from the update were combined and stratified by program focus (ie, reading-focused, math-focused, general academic programs, and programs with minimal academic focus). Focused programs were more effective than general or minimal academic programs. Reading-focused programs were effective only for students in grades K-3. There was insufficient evidence to determine effectiveness on behavioral outcomes and longer-term academic outcomes. 

**CONCLUSIONS: **
OSTA programs, particularly focused programs, are effective in increasing academic achievement for at-risk students. Ongoing school and social environments that support learning and development may be essential to ensure the longer-term benefits of OSTA programs.
AN  - 26062096
AU  - Knopf,
AU  - J.
AU  - A.
AU  - Hahn,
AU  - R.
AU  - A.
AU  - Proia,
AU  - K.
AU  - K.
AU  - Truman,
AU  - B.
AU  - I.
AU  - Johnson,
AU  - R.
AU  - I.
AU  - Muntaner,
AU  - C.
AU  - Fielding,
AU  - J.
AU  - E.
AU  - Jones,
AU  - C.
AU  - P.
AU  - Fullilove,
AU  - M.
AU  - T.
AU  - Hunt,
AU  - P.
AU  - C.
AU  - Qu,
AU  - S.
AU  - Chattopadhyay,
AU  - S.
AU  - K.
AU  - Milstein,
AU  - B.
AU  - The
AU  - Community
AU  - Preventive
AU  - Services
AU  - Task
AU  - Force
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/PHH.0000000000000268
L1  - internal-pdf://1452841303/Knopf-2015-Out-of-School-Time Academic Program.pdf
PY  - 2015
SP  - 594-608
TI  - Out-of-School-Time Academic Programs to Improve School Achievement: A Community Guide Health Equity Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26062096
VL  - 21
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Adolescence and early adulthood are critical periods for the development of mental disorders. Online peer-to-peer communication is popular among young people and may improve mental health by providing social support. Previous systematic reviews have targeted Internet support groups for adults with mental health problems, including depression. However, there have been no systematic reviews examining the effectiveness of online peer-to-peer support in improving the mental health of adolescents and young adults. 

**OBJECTIVE: **
The aim of this review was to systematically identify available evidence for the effectiveness of online peer-to peer support for young people with mental health problems. 

**METHODS: **
The PubMed, PsycInfo, and Cochrane databases were searched using keywords and Medical Subject Headings (MeSH) terms. Retrieved abstracts (n=3934) were double screened and coded. Studies were included if they (1) investigated an online peer-to-peer interaction, (2) the interaction discussed topics related to mental health, (3) the age range of the sample was between 12 to 25 years, and (4) the study evaluated the effectiveness of the peer-to-peer interaction. 

**RESULTS: **
Six studies satisfied the inclusion criteria for the current review. The studies targeted a range of mental health problems including depression and anxiety (n=2), general psychological problems (n=1), eating disorders (n=1), and substance use (tobacco) (n=2). The majority of studies investigated Internet support groups (n=4), and the remaining studies focused on virtual reality chat sessions (n=2). In almost all studies (n=5), the peer support intervention was moderated by health professionals, researchers or consumers. Studies employed a range of study designs including randomized controlled trials (n=3), pre-post studies (n=2) and one randomized trial. Overall, two of the randomized controlled trials were associated with a significant positive outcome in comparison to the control group at post-intervention. In the remaining four studies, peer-to-peer support was not found to be effective. 

**CONCLUSIONS: **
This systematic review identified an overall lack of high-quality studies examining online peer-to-peer support for young people. Given that peer support is frequently used as an adjunct to Internet interventions for a variety of mental health conditions, there is an urgent need to determine the effectiveness of peer support alone as an active intervention.
AD  - Ali, Kathina. National Institute for Mental Health Research The Australian National University Canberra Australia. Farrer, Louise. National Institute for Mental Health Research The Australian National University Canberra Australia. Gulliver, Amelia. National Institute for Mental Health Research The Australian National University Canberra Australia. Griffiths, Kathleen M. National Institute for Mental Health Research The Australian National University Canberra Australia.
AN  - 26543923
AU  - Ali,
AU  - K.
AU  - Farrer,
AU  - L.
AU  - Gulliver,
AU  - A.
AU  - Griffith,
AU  - K.
AU  - M.
DA  - Apr-Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2196/mental.4418
DP  - Ovid Technologies
J2  - JMIR Ment Health
L1  - internal-pdf://3789847540/4607385.epub
internal-pdf://0079396062/46073851.epub
internal-pdf://0661224873/Ali.pdf
LA  - English
M3  - Review
N1  - Ali, Kathina Farrer, Louise Gulliver, Amelia Griffiths, Kathleen M v2i2e19
PY  - 2015
SP  - e19
T2  - JMIR Mental Health
TI  - Online Peer-to-Peer Support for Young People With Mental Health Problems: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26543923http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26543923&amp;id=doi:10.2196%2Fmental.4418&amp;issn=2368-7959&amp;isbn=&amp;volume=2&amp;issue=2&amp;spage=e19&amp;pages=e19&amp;date=2015&amp;title=JMIR+Mental+Health&amp;atitle=Online+Peer-to-Peer+Support+for+Young+People+With+Mental+Health+Problems%3A+A+Systematic+Review.&amp;aulast=Ali&amp;pid=%3Cauthor%3EAli+K%3C%2Fauthor%3E%3CAN%3E26543923%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 2
ER  -
TY  - JOUR
AB  - **Bakgrunn** 
Antall barn under seks år som mottar tiltak fra barnevernet som følge av omsorgssvikt og mishandling har vært jevnt økende i perioden 1995-2008. Dette viser en rapport finansiert av Barne-, ungdoms- og familiedirektoratet som har sett på omfanget av omsorgssvikt når det kommer til sped- og småbarn i Norge. I 2008 var det 8256 barn under seks år som mottok tiltak fra barnevernet. Økningen har vært størst for barn under ett år. I rapporten fremkommer det at begrunnelsene for tiltak som benyttes mest er manglende omsorgsevne, foreldrenes rusmisbruk og foreldrenes psykiske helse. Det er behov for mer kunnskap om hva som har god effekt for barn i såkalte risikofamilier. 

**Metode** 
Vi søkte etter systematiske oversikter i 13 internasjonale databaser. Søket ble avsluttet i mars 2015. To forskere gikk uavhengig av hverandre gjennom alle titler og sammendrag og aktuelle publikasjoner ble vurdert i fulltekst. Vi inkluderte alle systematiske oversikter som vi vurderte til å ha høy metodisk kvalitet og som oppfylte våre inklusjonskriterer med hensyn til populasjon, tiltak og utfall. Vi benyttet oversiktsforfatternes vurdering av risiko for systematiske skjevheter i primærstudiene. Kvaliteten på dokumentasjonen ble vurdert til enten høy kvalitet (⨁⨁⨁⨁), middels kvalitet (⨁⨁⨁◯), lav kvalitet (⨁⨁◯◯), eller svært lav kvalitet(⨁◯◯◯). 

**Resultat** 
Vi inkluderte ni systematiske oversikter av høy metodisk kvalitet. Populasjonene i oversiktene har det til felles at de på ulike måter er sårbare familier med små barn. Tiltakene som er undersøkt i de inkluderte systematiske oversiktene i denne rapporten er delvis overlappende og delvis ulike. Vi grupperte resultatene i fem kategorier i henhold til type tiltak: 1) psykologiske, psykoedukative og psykososiale tiltak (tre oversikter), 2) foreldretiltak (to oversikter), 3) hjemmebesøk (to oversikter), 4) økonomiske tiltak (en oversikt), 5) mor-barn-enheter (en oversikt). Resultater fra de fire første presenteres her. Den femte kategorien kan vi ikke si noe om da den ene oversikten vi inkluderte ikke fant noen relevante studier. &Eacute;n systematisk oversikt så på effekt av psykoterapi (ulike terapiformer som har til hensikt å bedre psykisk helse hos den som mottar tiltaket) for mødre med depresjon. Forfatterne fant positiv effekt av tiltaket på psykisk helse hos både mor (Standardised Mean Difference (SMD)1 0,66, 95% konfidenintervall (KI): 0,46 &ndash; 0,84) (⨁⨁ ◯◯) og barn (SMD 0,40, 95% KI: 0,22 &ndash; 0,59) (⨁⨁◯◯), samt positiv effekt på samspill mellom mor og barn (SMD 0,35, 95% KI: 0,17 &ndash; 0,52) (⨁⨁◯◯). En annen systematisk oversikt så på effekt av både psykoterapi, psykoedukative tiltak (opplæring i sykdommen samt teknikker for å håndtere den) og psykososiale tiltak (inkluderer hele familien og fokuserer på hvordan hele familien kan håndtere situasjonen) til familier der minst en av foreldrene led av alvorlig depresjon. De fant ingen effekt av tiltakene på barnets emosjonelle helse (SMD 0,06, 95% KI: -0,2 &ndash; 0,33) (⨁⨁◯◯ ). &Eacute;n systematisk oversikt så på effekt av psykoterapi for mødre og spedbarn (tiltaket gis til mor og barn sammen og fokuserer på samspill mellom mor og barn og mors evne til å se barnets signaler og møte barnets behov). Forfatterne fant en sterk positiv effekt av tiltaket på tilknytningsstil (trygg eller utrygg tilknytning til omsorgsperson) hos barnet (RR 3,30, 95% KI: 1,82 &ndash; 6,00) (⨁⨁◯◯). &Eacute;n systematisk oversikt så på effekt av foreldretiltak (veiledning i foreldrerollen og hvordan samspille bedre med barnet) til familier som er i kontakt med barnevernet på grunn av mishandling/omsorgssvikt. Forfatterne fant at tiltaket har positiv effekt på foreldre-barn-relasjonen, men vi mangler effektstørrelse og konfidensintervall (⨁⨁◯◯), mens resultatene for barnets atferd og mentale helse er sprikende (⨁⨁◯ ◯). &Eacute;n systematisk oversikt så på effekt av foreldretrening for foreldre med psykisk utviklingshemming. Forfatterne fant at tiltaket har positiv effekt på evne til å håndtere farlige situasjoner (MD 1,95, 95% KI: 0,46 &ndash; 3,44) (⨁⨁◯◯). De fant ingen effekt av tiltaket for utfall knyttet til helseforståelse (MD -0,7, 95% KI: -1,29 &ndash; 0,11) (⨁⨁◯◯). De fant imidlertid en effekt av tiltaket på mor-barn-samspill, men her mangler vi effektstørrelse og konfidensintervall (⨁◯◯◯). &Eacute;n systematisk oversikt så på effekt av hjemmebesøk (sykepleiere eller sosalarbeidere besøker familier med små barn og gir veiledning og støtte til foreldre) hos familier som er i risiko for omsorgssvikt og misbruk av barn. Resultater for utfall som mishandling og omsorgssvikt er sprikende. Resultater for utfall som barnets atferd og barnets kognitive og språklige utvikling er også sprikende. Her mangler vi effektstørrelser og konfidensintervaller (⨁⨁◯◯). &Eacute;n systematisk oversikt så på effekt av hjemmebesøk for mødre med rusmiddelproblemer. De fant at tiltaket har liten eller ingen effekt på mors rusmisbruk (RR 1,18, 95% KI: 0,96 &ndash; 1,46) (⨁⨁◯◯), på utfall knyttet til mishandling/omsorgssvikt (RR 0,36, 95% KI: 0,02 &ndash; 8,77) (⨁⨁◯◯) eller atferdsproblemer hos barnet (RR 0,46, 95% KI: 0,21 &ndash; 1,01) (⨁⨁◯◯). &Eacute;n systematisk oversikt så på effekt av økonomiske tiltak til familier med lav sosioøkonomisk status. Forfatterne fant at tiltaket har liten eller ingen effekt på hvorvidt barnet utsettes for fysisk skade (OR 1,06, 95% KI: 0,82 &ndash; 1,35) (⨁⨁⨁◯). De fant 1 Se vedlegg 6 for forklaringer av statistiske begreper og andre begreper også at tiltaket har liten eller ingen effekt på positiv atferd hos barnet (OR 0,96, 95% KI: 0,79 &ndash; 1,17) (⨁⨁◯◯). 

**Diskusjon** 
På grunn av svakheter i gjennomføring av studiene, noe frafall fra studiene samt at studiene gjennomgående hadde få deltakere, har vi generelt lav tillit til dokumentasjonen. Det betyr ikke at tiltakene er uten effekt, men at datagrunnlaget er for svakt til at vi kan si noe med sikkerhet. Av spesielle forhold ved de fem kategoriene kan det trekkes frem at: &bull; Psykologiske tiltak ser ut til å ha bedre effekt på foreldre og barns psykiske helse enn psykoedukative eller psykososiale tiltak. Psykoterapi for både mor og spedbarn ser ut til å ha en sterk positiv effekt på tilknytningsstil hos barnet, sammenlignet med standard tjenestetilbud. Når tiltaket sammenlignes med annet aktivt foreldretiltak viser dette tiltaket like god effekt. Annet aktivt foreldretiltak kan således ha like god effekt. &bull; Foreldretiltak ser ut til å ha positiv effekt på foreldre-barn-relasjonen, men tiltakene viser blandede resultater for andre utfallsmål. Tiltakenes innhold bør muligens tilpasses den enkelte gruppe i større grad. &bull; Hjemmebesøk ser ut til å ha liten effekt for mødre med rusmiddelproblemer. Mens det viser blandede resultater for andre grupper. Tiltaket kan muligens fungere bedre dersom det settes inn tidlig, den som leverer tiltaket er godt trenet på å møte utfordringene i de aktuelle familiene, tiltaket leveres over en viss tid og fokuserer på få elementer/utfordringer heller enn et spekter av utfordringer. &bull; Økonomisk tiltak ser ut til å ha liten eller ingen effekt på forhold som gjelder mishandling eller atferdsproblemer hos barn. Tiltaket alene er trolig ikke nok til å endre livsbetingelsene/familieforholdene til familier med lav sosioøkonomisk status, i alle fall ikke dersom tilskuddet som gis er såpass lite at handlingsrommet i svært begrenset grad utvides. &bull; Mor-barn-enheter kan vi ikke si noe om da oversikten inkluderte 0 studier. Studiene vi har oppsummert resultater fra her er i stor grad utført i USA, Storbritannia eller andre land med langt større fattigdom og sosioøkonomiske utfordringer enn det vi har i Norge. Kanskje vil norske familier - som lever i en velferdsstat - i større grad enn familier i USA kunne nyttegjøre seg enkelte tiltak fordi mengden stress knyttet til sosioøkonomiske utfordringer osv. i familiene kan være mindre. 

**Konklusjon** 
Vi fant ni systematiske oversikter av høy metodisk kvalitet som tilfredsstilte våre inklusjonskriterier. Tiltakene grupperte vi i fem kategorier. Av disse viste tre hovedkategorier av tiltak muligens effekt på minst ett utfallsmål: Psykologiske, psykoedukative og psykososiale tiltak, foreldretiltak og hjemmebesøk. Det ble ikke rapportert om negative utfall. Små økonomiske tilskudd har trolig liten eller ingen effekt. Oversikten som så på mor-barn-enheter fant ingen studier å inkludere i oversikten, så for denne typen tiltak kan vi ikke trekke noen konklusjoner.
AU  - Blaasvær,
AU  - N.
AU  - Nøkleby,
AU  - H.
AU  - Johansen,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/rapport_2015_27_risikofamilier%20(1).pdf
PY  - 2015
T2  - Folkehelseinstituttet
TI  - Effekt av tiltak for risikofamilier med barn 0-6 år
ER  -
TY  - JOUR
AB  - **Background:**
Child and adolescent overweight and obesity have increased globally, and are associated with short- and long-term health consequences.

**Objectives:** 
To assess the efficacy of diet, physical activity and behavioural interventions delivered to parents only for the treatment of overweight and obesity in children aged 5 to 11 years.

**Search methods:** 
We performed a systematic literature search of databases including the Cochrane Library, MEDLINE, EMBASE, PsycINFO, CINAHL and LILACS as well trial registers. We checked references of identified trials and systematic reviews. We applied no language restrictions. The date of the last search was March 2015 for all databases.

**Selection criteria:** 
We selected randomised controlled trials (RCTs) of diet, physical activity and behavioural interventions delivered to parents only for treating overweight or obesity in children aged 5 to 11 years.

**Data collection and analysis:** 
Two review authors independently assessed trials for risk of bias and evaluated overall study quality using the GRADE instrument. Where necessary, we contacted authors for additional information.

**Main results:** 
We included 20 RCTs, including 3057 participants. The number of participants ranged per trial between 15 and 645. Follow-up ranged between 24 weeks and two years. Eighteen trials were parallel RCTs and two were cluster RCTs. Twelve RCTs had two comparisons and eight RCTs had three comparisons. The interventions varied widely; the duration, content, delivery and follow-up of the interventions were heterogeneous. The comparators also differed. This review categorised the comparisons into four groups: parent-only versus parent-child, parent-only versus waiting list controls, parent-only versus minimal contact interventions and parent-only versus other parent-only interventions.Trial quality was generally low with a large proportion of trials rated as high risk of bias on individual risk of bias criteria.In trials comparing a parent-only intervention with a parent-child intervention, the body mass index (BMI) z score change showed a mean difference (MD) at the longest follow-up period (10 to 24 months) of -0.04 (95% confidence interval (CI) -0.15 to 0.08); P = 0.56; 267 participants; 3 trials; low quality evidence. In trials comparing a parent-only intervention with a waiting list control, the BMI z score change in favour of the parent-only intervention at the longest follow-up period (10-12 months) had an MD of -0.10 (95% CI -0.19 to -0.01); P = 0.04; 136 participants; 2 trials; low quality evidence. BMI z score change of parent-only interventions when compared with minimal contact control interventions at the longest follow-up period (9 to 12 months) showed an MD of 0.01 (95% CI -0.07 to 0.09); P = 0.81; 165 participants; 1 trial; low quality evidence. There were few similarities between interventions and comparators across the included trials in the parent-only intervention versus other parent-only interventions and we did not pool these data. Generally, these trials did not show substantial differences between their respective parent-only groups on BMI outcomes.Other outcomes such as behavioural measures, parent-child relationships and health-related quality of life were reported inconsistently. Adverse effects of the interventions were generally not reported, two trials stated that there were no serious adverse effects. No trials reported on all-cause mortality, morbidity or socioeconomic effects.All results need to be interpreted cautiously because of their low quality, the heterogeneous interventions and comparators, and the high rates of non-completion.

**Authors&#039; conclusions:** 
Parent-only interventions may be an effective treatment option for overweight or obese children aged 5 to 11 years when compared with waiting list controls. Parent-only interventions had similar effects compared with parent-child interventions and compared with those with minimal contact controls. However, the evidence is at present limited; some of the trials had a high risk of bias with loss to follow-up being a particular iss e and there was a lack of evidence for several important outcomes. The systematic review has identified 10 ongoing trials that have a parent-only arm, which will contribute to future updates. These trials will improve the robustness of the analyses by type of comparator, and may permit subgroup analysis by intervention component and the setting. Trial reports should provide adequate details about the interventions to be replicated by others. There is a need to conduct and report cost-effectiveness analyses in future trials in order to establish whether parent-only interventions are more cost-effective than parent-child interventions.
AN  - CD012008
AU  - Loveman,
AU  - E.
AU  - Al-Khudairy,
AU  - L.
AU  - Johnson,
AU  - R.
AU  - E.
AU  - Robertson,
AU  - W.
AU  - Mead,
AU  - E.
AU  - L.
AU  - Ells,
AU  - L.
AU  - J.
AU  - Metzendorf,
AU  - M.
AU  - I.
AU  - Rees,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd012008
KW  - Body Mass Index
KW  - Body Weight
KW  - Health Status
KW  - Overweight [therapy]
KW  - Parents [education]
KW  - Pediatric Obesity [therapy]
KW  - Quality of Life
KW  - Randomized Controlled Trials as Topic
KW  - Self Concept
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Endoc
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Parent-only interventions for childhood overweight or obesity in children aged 5 to 11 years
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD012008/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD012008/asset/CD012008.pdf?v=1&amp;t=iw7khpdn&amp;s=b2cec3ffa99c241248ff54e28b95bd969fefadf6
ER  -
TY  - JOUR
AB  - This guidance paper from the European Psychiatric Association (EPA) aims to provide evidence-based recommendations on early intervention in clinical high risk (CHR) states of psychosis, assessed according to the EPA guidance on early detection. 

The recommendations were derived from a meta-analysis of current empirical evidence on the efficacy of psychological and pharmacological interventions in CHR samples. Eligible studies had to investigate conversion rate and/or functioning as a treatment outcome in CHR patients defined by the ultra-high risk and/or basic symptom criteria. Besides analyses on treatment effects on conversion rate and functional outcome, age and type of intervention were examined as potential moderators. 
Based on data from 15 studies (n=1394), early intervention generally produced significantly reduced conversion rates at 6- to 48-month follow-up compared to control conditions. 

However, early intervention failed to achieve significantly greater functional improvements because both early intervention and control conditions produced similar positive effects. With regard to the type of intervention, both psychological and pharmacological interventions produced significant effects on conversion rates, but not on functional outcome relative to the control conditions. 

Early intervention in youth samples was generally less effective than in predominantly adult samples. Seven evidence-based recommendations for early intervention in CHR samples could have been formulated, although more studies are needed to investigate the specificity of treatment effects and potential age effects in order to tailor interventions to the individual treatment needs and risk status. 

Copyright &copy; 2015 Elsevier Masson SAS. All rights reserved.
AD  - Schmidt,S J. University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland. Schultze-Lutter,F. University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland. Schimmelmann,B G. University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland. Maric,N P. School of Medicine, University of Belgrade and Clinic of Psychiatry, Clinical Center of Serbia, Belgrade, Serbia. Salokangas,R K R. Department of Psychiatry, University of Turku, Turku, Finland. Riecher-Rossler,A. Center for Gender Research and Early Detection, Psychiatric University Clinics of Basel, Basel, Switzerland. van der Gaag,M. Department of Clinical Psychology, VU University and EMGO Institute for Health and Care Research, Amsterdam, The Netherlands; Psychosis Research, Parnassia Psychiatric Institute, Hague, The Netherlands. Meneghelli,A. Dipartimento di Salute Mentale, Centro per l&#039;Individuazione e l&#039;Intervento Precoce nelle Psicosi-Programma 2000, Ospedale Niguarda Ca&#039; Granda, Milan, Italy. Nordentoft,M. Mental Health Center of Copenhagen, University of Copenhagen, Copenhagen, Denmark. Marshall,M. School of Medicine, University of Manchester, Manchester, UK; LANTERN Center, Lancashire Care NHS Foundation Trust, Preston, UK. Morrison,A. School of Psychological Sciences, University of Manchester, Manchester, UK; Psychosis Research Unit, Greater Manchester West NHS Mental Health Trust, Manchester, UK. Raballo,A. Department of Mental Health, Reggio Emilia Public Health Center, Reggio Emilia, Italy; Regional Working Group on Early Detection of Psychosis, Emilia Romagna Regional Health Service, Bologna, Italy. Klosterkotter,J. Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany. Electronic address: Joachim.klosterkotter@uk-koeln.de. Ruhrmann,S. Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.
AN  - 25749390
AU  - Schmidt,
AU  - S.
AU  - J.
AU  - Schultze-Lutter,
AU  - F.
AU  - Schimmelmann,
AU  - B.
AU  - G.
AU  - Maric,
AU  - N.
AU  - P.
AU  - Salokangas,
AU  - R.
AU  - K.
AU  - Riecher-Rossler,
AU  - A.
AU  - van
AU  - der
AU  - Gaag,
AU  - M.
AU  - Meneghelli,
AU  - A.
AU  - Nordentoft,
AU  - M.
AU  - Marshall,
AU  - M.
AU  - Morrison,
AU  - A.
AU  - Raballo,
AU  - A.
AU  - Klosterkotter,
AU  - J.
AU  - Ruhrmann,
AU  - S.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.eurpsy.2015.01.013
DP  - Ovid Technologies
J2  - Eur Psychiatry
LA  - English
N1  - Schmidt, S J Schultze-Lutter, F Schimmelmann, B G Maric, N P Salokangas, R K R Riecher-Rossler, A van der Gaag, M Meneghelli, A Nordentoft, M Marshall, M Morrison, A Raballo, A Klosterkotter, J Ruhrmann, S S0924-9338(15)00057-7
PY  - 2015
SP  - 388-404
T2  - European Psychiatry: the Journal of the Association of European Psychiatrists
TI  - EPA guidance on the early intervention in clinical high risk states of psychoses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25749390 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25749390&amp;id=doi:10.1016%2Fj.eurpsy.2015.01.013&amp;issn=0924-9338&amp;isbn=&amp;volume=30&amp;issue=3&amp;spage=388&amp;pages=388-404&amp;date=2015&amp;title=European+Psychiatry%3A+the+Journal+of+the+Association+of+European+Psychiatrists&amp;atitle=EPA+guidance+on+the+early+intervention+in+clinical+high+risk+states+of+psychoses.&amp;aulast=Schmidt&amp;pid=%3Cauthor%3ESchmidt+SJ%3C%2Fauthor%3E%3CAN%3E25749390%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0924933815000577/1-s2.0-S0924933815000577-main.pdf?_tid=f0c8dfc2-18db-11e5-bfe8-00000aacb361&amp;acdnat=1434977042_e0cdbb8fc30932e34aab673db96974e3
VL  - 30
ER  -
TY  - JOUR
AB  - **Background: **
Mindfulness-based interventions (MBIs) are increasingly used in the management of various mental health disorders in children and adolescents. However, there is limited evidence about the efficacy of various interventions used. 

**Method: **
A systematic review was performed to examine the effects of different MBIs on mental health symptoms and quality of life in both clinical and nonclinical samples of children and adolescents using data from only randomized control trials. The studies were also assessed for quality. Based on the type of MBI, study population, and control arm we had three comparisons for meta-analyses. 

**Results: **
Fifteen studies were included in the qualitative analysis but only 11 trials with comparable interventions and controls were included for meta-analyses. Mindfulness-based stress reduction/mindfulness-based cognitive therapy arm was more effective than nonactive control in the nonclinical populations. Acceptance commitment therapy was comparable to active treatments in patients in the clinical range. Other MBIs were also effective improving anxiety and stress but not depression in nonclinical populations compared to nonactive control. 

**Conclusions: **
Mindfulness-based interventions can be effective in children and adolescents with mental health symptoms. As there were significant limitations these results must be interpreted with caution. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Kallapiran, Kannan: sgkkan@yahoo.co.in Kallapiran, Kannan: Children&#039;s Hospital at Westmead, Sydney Children&#039;s Hospital Network, Locked Bag 4001, Westmead, NSW, Australia, 2145, sgkkan@yahoo.co.in Kallapiran, Kannan: Children&#039;s Hospital at Westmead, Sydney Children&#039;s Hospital Network, Westmead, NSW, Australia Koo, Siew: Children&#039;s Hospital at Westmead, Sydney Children&#039;s Hospital Network, Westmead, NSW, Australia Kirubakaran, Richard: South Asian Cochrane Network, Vellore, India Hancock, Karen: Children&#039;s Hospital at Westmead, Sydney Children&#039;s Hospital Network, Westmead, NSW, Australia
AN  - 2015-41718-001
AU  - Kallapiran,
AU  - K.
AU  - Koo,
AU  - S.
AU  - Kirubakaran,
AU  - R.
AU  - Hancock,
AU  - K.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/camh.12113
DP  - Ovid Technologies
KW  - Meditation, mindfulness interventions, yoga, therapy, RCTs
KW  - *Intervention
KW  - *Mental Health
KW  - *Quality of Life
KW  - *Mindfulness
KW  - Symptoms
KW  - Yoga
KW  - Psychotherapy &amp; Psychotherapeutic Counseling [3310]
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://1258232797/Kallapiran_et_al-2015-Child_and_Adolescent_Men.pdf
LA  - English
M3  - Meta Analysis
PY  - 2015
SP  - 182-194
T2  - Child and Adolescent Mental Health
TI  - Review: Effectiveness of mindfulness in improving mental health symptoms of children and adolescents: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-41718-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1111%2Fcamh.12113&amp;issn=1475-357X&amp;isbn=&amp;volume=20&amp;issue=4&amp;spage=182&amp;pages=182-194&amp;date=2015&amp;title=Child+and+Adolescent+Mental+Health&amp;atitle=Review%3A+Effectiveness+of+mindfulness+in+improving+mental+health+symptoms+of+children+and+adolescents%3A+A+meta-analysis.&amp;aulast=Kallapiran&amp;pid=%3Cauthor%3EKallapiran%2C+Kannan%3C%2Fauthor%3E%3CAN%3E2015-41718-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 20
ER  -
TY  - JOUR
AB  - **Objective **
To perform a systematic review and meta-analysis for the effects of physical activity intervention on self-esteem and self-concept in children and adolescents, and to identify moderator variables by meta-regression. 

**Design **
A meta-analysis and meta-regression. 

**Method **
Relevant studies were identified through a comprehensive search of electronic databases. Study inclusion criteria were: (1) intervention should be supervised physical activity, (2) reported sufficient data to estimate pooled effect sizes of physical activity intervention on self-esteem or self-concept, (3) participants&#039; ages ranged from 3 to 20 years, and (4) a control or comparison group was included. For each study, study design, intervention design and participant characteristics were extracted. R software (version 3.1.3) and Stata (version 12.0) were used to synthesize effect sizes and perform moderation analyses for determining moderators. 

**Results **
Twenty-five randomized controlled trial (RCT) studies and 13 non-randomized controlled trial (non-RCT) studies including a total of 2991 cases were identified. Significant positive effects were found in RCTs for intervention of physical activity alone on general self outcomes (Hedges&#039; g = 0.29, 95% confidence interval [CI]: 0.14 to 0.45; p = 0.001), self-concept (Hedges&#039; g = 0.49, 95% CI: 0.10 to 0.88, p = 0.014) and self-worth (Hedges&#039; g = 0.31, 95% CI: 0.13 to 0.49, p = 0.005). There was no significant effect of intervention of physical activity alone on any outcomes in non-RCTs, as well as in studies with intervention of physical activity combined with other strategies. Meta-regression analysis revealed that higher treatment effects were associated with setting of intervention in RCTs (beta = 0.31, 95% CI: 0.07 to 0.55, p = 0.013). 

**Conclusion **
Intervention of physical activity alone is associated with increased self-concept and self-worth in children and adolescents. And there is a stronger association with school-based and gymnasium-based intervention compared with other settings.
AD  - [Liu, Mingli; Ming, Qingsen] Cent S Univ, Xiangya Hosp 2, Inst Med Psychol, Changsha 410011, Hunan, Peoples R China. [Liu, Mingli] Hunan Univ Sci &amp; Technol, Sch Educ, Xiangtan 411201, Hunan, Peoples R China. [Wu, Lang] Mayo Clin, Ctr Clin &amp; Translat Sci, Rochester, MN 55905 USA. Liu, ML (reprint author), Cent S Univ, Xiangya Hosp 2, Inst Med Psychol, Changsha 410011, Hunan, Peoples R China. mlliupsy@163.com
AN  - WOS:000358942700068
AU  - Liu,
AU  - M.
AU  - Wu,
AU  - L.
AU  - Ming,
AU  - Q.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1371/journal.pone.0134804
J2  - PLoS One
KW  - randomized controlled-trial
KW  - body-composition
KW  - overweight children
KW  - publication bias
KW  - cerebral-palsy
KW  - mental-health
KW  - young-people
KW  - depression
KW  - exercise
KW  - program
KW  - Science &amp; Technology - Other Topics
L1  - internal-pdf://2080064253/Liu-2015-How Does Physical Activity Interventi.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: CO1VB Times Cited: 12 Cited Reference Count: 56 Liu, Mingli Wu, Lang Ming, Qingsen Hunan Provincial Education Department [914 \ B41120] This research was supported by Scientific Research Fund of Hunan Provincial Education Department (grant number 914 vertical bar B41120) (URL:
PY  - 2015
SP  - 17
T2  - Plos One
TI  - How Does Physical Activity Intervention Improve Self-Esteem and Self-Concept in Children and Adolescents? Evidence from a Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000358942700068
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0134804&amp;type=printable
VL  - 10
ER  -
TY  - JOUR
AB  - **Objective: **
this systematic review assessed the safety and efficacy of olanzapine-fluoxetine combination (OFC) for treatment of bipolar depression, specifically in studies of 8 to 12 weeks duration in adults (primary objective) and adolescents (secondary objective). 

**Materials and methods: **
trials were identified using MEDLINE, EMBASE, Cochrane Library, Web of Knowledge, LILACS, WHOLIS, NEURO, Latindex, and DIALNET (2000 &ndash; July 2014). English and Spanish free-text and MeSH terms were used. Searches were supplemented with identified trials (Clinical Trials.gov) and congress abstracts. Evidence from randomized controlled trials (RCTs), nonrandomized trials, and meta-analyses were considered. 

**Results: **
nine publications reporting 5 RCTs (6 publications), 1 nonrandomized trial, and 2 metaanalyses were included. One RCT was conducted in adolescents and one RCT was conducted in a Latin American population. Studies enrolled from 34 to 833 participants, were conducted for 7 to 8 weeks and up to 6 months, and varied in methodological quality and reporting. The efficacy of OFC (depression rating scales, response and remission rates) was greater compared with olanzapine monotherapy, lamotrigine monotherapy, and placebo. OFC was well tolerated in adults and adolescents. However, there was a greater frequency of weight gain, somnolence, nausea, diarrhea, and elevated metabolic parameters in participants receiving OFC versus active comparators or placebo.

**Conclusions: **
this systematic review presents findings that OFC is effective and generally well tolerated for acute treatment of bipolar depression in adults and adolescents. Existing evidence suggests that the efficacy and safety profile of OFC in patients from Latin America is not different to Caucasian populations.
AN  - 614995561
AU  - Vargas-Huicochea,
AU  - I.
AU  - Tamayo,
AU  - J.
AU  - M.
AU  - Ruiz,
AU  - I.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.google.com/search?q=A+systematic+review+of+combined+olanzapine-fluoxetine+as+therapy+for+bipolar+depression+in+adult+and+adolescent+patients&amp;rlz=1C1GCEA_enNO796NO796&amp;oq=A+systematic+review+of+combined+olanzapine-fluoxetine+as+therapy+for+bipolar+depression+in+adult+and+adolescent+patients&amp;aqs=chrome..69i57j69i64l3.694j0j7&amp;sourceid=chrome&amp;ie=UTF-8
L1  - internal-pdf://3021819600/Vargas-Huicoche-2015-A systematic review of co.pdf
PY  - 2015
SP  - 122-136
TI  - A systematic review of combined olanzapine-fluoxetine as therapy for bipolar depression in adult and adolescent patients
UR  - http://www.medigraphic.com/pdfs/arcneu/ane-2015/ane152e.pdf
VL  - 20
ER  -
TY  - JOUR
AB  - Approximately 20 years ago O&#039;Donohue and Elliott (1992) reviewed the treatment outcome literature for sexually abused children and evaluated each study on several criteria (e.g., adequacy of the description of therapy, subjects, and research design; assessment of clinical significance and social validity; inclusion of follow-up assessment to establish the durability of treatment effects etc.). 

At that time they were only able to identify 11 treatment outcome studies. Currently, a similar search has yielded several hundred outcome studies related to the treatment of child sexual abuse, several reviews of the literature, and seven relevant meta-analyses, clearly indicating a proliferation of much needed outcome research. 

In this paper we critically reviewed the seven meta-analyses and noted that different criteria for inclusion were used and some cases quite different conclusions were drawn. In this paper we describe and evaluate the seven meta-analyses and provide evidence-based treatment recommendations for children and adolescents who have been sexually abused. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Benuto, Lorraine T.: dr.benuto@gmail.com; O&#039;Donohue, William: wto@unr.edu Benuto, Lorraine T.: University of Nevada, Reno, MS 0298, Reno, NV, US, 89557, dr.benuto@gmail.com Benuto, Lorraine T.: University of Nevada, Reno, Reno, NV, US O&#039;Donohue, William: University of Nevada, Reno, Reno, NV, US
AN  - 2015-37644-008
AU  - Benuto,
AU  - L.
AU  - T.
AU  - O&#039;Donohue,
AU  - W.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2015.06.009
DP  - Ovid Technologies
KW  - Meta analyses, Treatment review, Treatment of child sexual abuse
KW  - *Child Abuse
KW  - *Sexual Abuse
KW  - *Treatment Outcomes
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human Childhood (birth-12 yrs) Preschool Age (2-5 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older) Young Adulthood (18-29 yrs)
L1  - internal-pdf://0738825529/Benuto-2015-Treatment of the sexually abused c.pdf
LA  - English
M3  - Literature Review
PY  - 2015
SP  - 52-60
T2  - Children and Youth Services Review
TI  - Treatment of the sexually abused child: Review and synthesis of recent meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-37644-008http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2015.06.009&amp;issn=0190-7409&amp;isbn=&amp;volume=56&amp;issue=&amp;spage=52&amp;pages=52-60&amp;date=2015&amp;title=Children+and+Youth+Services+Review&amp;atitle=Treatment+of+the+sexually+abused+child%3A+Review+and+synthesis+of+recent+meta-analyses.&amp;aulast=Benuto&amp;pid=%3Cauthor%3EBenuto%2C+Lorraine+T%3C%2Fauthor%3E%3CAN%3E2015-37644-008%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0190740915001929/1-s2.0-S0190740915001929-main.pdf?_tid=90b8fa8e-04c2-11e7-8fb1-00000aacb35f&amp;acdnat=1489062115_cbab2b8cccd2f8465a740e58f0e2ca7a
VL  - 56
ER  -
TY  - JOUR
AB  - **Background and objectives: **
Services have variable practices for identifying and providing interventions for &#039;severe attachment problems&#039; (disorganised attachment patterns and attachment disorders). Several government reports have highlighted the need for better parenting interventions in at-risk groups. This report was commissioned to evaluate the clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems (the main review). One supplementary review explored the evaluation of assessment tools and a second reviewed 10-year outcome data to better inform health economic aspects of the main review. 

**Data sources: **
A total of 29 electronic databases were searched with additional mechanisms for identifying a wide pool of references using the Cochrane methodology. Examples of databases searched include PsycINFO (1806 to January week 1, 2012), MEDLINE and MEDLINE In-Process &amp; Other Non-Indexed Citations (1946 to December week 4, 2011) and EMBASE (1974 to week 1, 2012). Searches were carried out between 6 and 12 January 2012. 

**Review methods: **
Papers identified were screened and data were extracted by two independent reviewers, with disagreements arbitrated by a third independent reviewer. Quality assessment tools were used, including quality assessment of diagnostic accuracy studies - version 2 and the Cochrane risk of bias tool. Meta-analysis of randomised controlled trials (RCTs) of parenting interventions was undertaken. A health economics analysis was conducted. 

**Results: **
The initial search returned 10,167 citations. This yielded 29 RCTs in the main review of parenting interventions to improve attachment patterns, and one involving children with reactive attachment disorder. A meta-analysis of eight studies seeking to improve outcome in at-risk populations showed statistically significant improvement in disorganised attachment. The interventions saw less disorganised attachment at outcome than the control (odds ratio 0.47, 95% confidence interval 0.34 to 0.65; p &lt; 0.00001). Much of this focused around interventions improving maternal sensitivity, with or without video feedback. In our first supplementary review, 35 papers evaluated an attachment assessment tool demonstrating validity or psychometric data. Only five reported test-retest data. Twenty-six studies reported inter-rater reliability, with 24 reporting a level of 0.7 or above. Cronbach&#039;s alphas were reported in 12 studies for the comparative tests (11 with alpha &gt; 0.7) and four studies for the reference tests (four with alpha &gt; 0.7). Three carried out concurrent validity comparing the Strange Situation Procedure (SSP) with another assessment tool. These had good sensitivity but poor specificity. The Disturbances of Attachment Interview had good sensitivity and specificity with the research diagnostic criteria (RDC) for attachment disorders. In our supplementary review of 10-year outcomes in cohorts using a baseline reference standard, two studies were found with disorganised attachment at baseline, with one finding raised psychopathology in adolescence. Budget impact analysis of costs was estimated because a decision model could not be justifiably populated. This, alongside other findings, informed research priorities. 

**Limitations: **
There are relatively few UK-based clinical trials. A 10-year follow-up, while necessary for our health economists for long-term sequelae, yielded a limited number of papers. 

**Conclusions: **
Maternal sensitivity interventions show good outcomes in at-risk populations, but require further research with complex children. The SSP and RDC for attachment disorders remain the reference standards for identification until more concurrent and predictive validity research is conducted. A birth cohort with sequential attachment measures and outcomes across different domains is recommended with further, methodologically sound randomised controlled intervention trials. The main area identified for future work was a need for good-quality RCTs in at-risk groups such as those entering foster care or doption.
AD  - [Wright, Barry; Allgar, Victoria; Manea, Laura; McMillan, Dean; Gilbody, Simon] Univ York, Hull York Med Sch, York YO10 5DD, N Yorkshire, England. [Wright, Barry; Barry, Melissa; Hughes, Ellen; Cottrill, Lucy; Fell, Jenny; Hackney, Lisa] NHS Fdn Trust, Leeds &amp; York Partnership, Leeds, W Yorkshire, England. [Trepel, Dominic; Ali, Shehzad; Fell, Jenny; McMillan, Dean; Perry, Amanda; Gilbody, Simon] Univ York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England. [Duffy, Steven; Glanville, Julie] York Hlth Econ Consortium, York, N Yorkshire, England. [Glaser, Danya] Great Ormond St Hosp Sick Children, London, England. [Glaser, Danya] UCL, Res Dept Clin Educ &amp; Hlth Psychol, London, England. [Palmer, Stephen] Univ York, Ctr Hlth Econ, York YO10 5DD, N Yorkshire, England. [Prior, Vivien] UCL, Inst Child Hlth, Fac Populat Hlth Sci, London, England. [Whitton, Clare] Esk &amp; Wear Valleys NHS Fdn Trust, Tees, Middlesbrough, Cleveland, England. Wright, B (reprint author), Univ York, Hull York Med Sch, York YO10 5DD, N Yorkshire, England. barry.wright1@nhs.net
AN  - WOS:000357979700001
AU  - Wright,
AU  - B.
AU  - Barry,
AU  - M.
AU  - Hughes,
AU  - E.
AU  - Trepel,
AU  - D.
AU  - Ali,
AU  - S.
AU  - Allgar,
AU  - V.
AU  - Cottrill,
AU  - L.
AU  - Duffy,
AU  - S.
AU  - Fell,
AU  - J.
AU  - Glanville,
AU  - J.
AU  - Glaser,
AU  - D.
AU  - Hackney,
AU  - L.
AU  - Manea,
AU  - L.
AU  - McMillan,
AU  - D.
AU  - Palmer,
AU  - S.
AU  - Prior,
AU  - V.
AU  - Whitton,
AU  - C.
AU  - Perry,
AU  - A.
AU  - Gilbody,
AU  - S.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3310/hta19520
J2  - Health Technol. Assess.
KW  - infant-mother attachment
KW  - early head-start
KW  - at-risk mothers
KW  - randomized
KW  - controlled-trial
KW  - maternal-fetal attachment
KW  - birth-weight infants
KW  - strange-situation procedure
KW  - home-visiting intervention
KW  - to-skin
KW  - contact
KW  - postpartum bonding questionnaire
KW  - Health Care Sciences &amp; Services
L1  - internal-pdf://3911970509/3002738(1).pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CM8VG Times Cited: 0 Cited Reference Count: 1174 Wright, Barry Barry, Melissa Hughes, Ellen Trepel, Dominic Ali, Shehzad Allgar, Victoria Cottrill, Lucy Duffy, Steven Fell, Jenny Glanville, Julie Glaser, Danya Hackney, Lisa Manea, Laura McMillan, Dean Palmer, Stephen Prior, Vivien Whitton, Clare Perry, Amanda Gilbody, Simon Duffy, Steven/E-2327-2016; Duffy, Steven/0000-0001-7335-8167; Allgar, Victoria/0000-0002-5228-2623; Glanville, Julie/0000-0002-1253-8524 National Institute for Health Research Health Technology Assessment programme The National Institute for Health Research Health Technology Assessment programme. 0 20 62 Nihr journals library Southampton 2046-4924
PY  - 2015
SP  - 1-+
T2  - Health Technology Assessment
TI  - Clinical effectiveness and cost-effectiveness of parenting interventions for children with severe attachment problems: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000357979700001
VL  - 19
ER  -
TY  - JOUR
AB  - **Background **
Individual randomized controlled trials (RCTs) have demonstrated the efficacy of cognitive behavioral therapy (CBT) and serotonin reuptake inhibitors (SRIs) for the treatment of youth with obsessive-compulsive disorder (OCD). Although meta-analyses have confirmed these results, there has been minimal examination of treatment moderators or an examination of treatment response and symptom/diagnostic remission for these two treatment types. The present report examined the treatment efficacy, treatment response, and symptom/diagnostic remission for youth with OCD receiving either CBT or SRIs relative to comparison conditions, and examined treatment moderators. 

**Method **
A comprehensive literature search identified 20 RCTs that met inclusion criteria, and produced a sample size of 507 CBT participants and 789 SRI participants. 

**Results **
Random effects meta-analyses of CBT trials found large treatment effects for treatment efficacy (g = 1.21), treatment response (relative risk [RR] = 3.93), and symptom/diagnostic remission (RR = 5.40). Greater co-occurring anxiety disorders, therapeutic contact, and lower treatment attrition were associated with greater CBT effects. The number needed to treat (NNT) was three for treatment response and symptom/diagnostic remission. Random effects meta-analyses of SRI trials found a moderate treatment effect for treatment efficacy (g = 0.50), treatment response (RR = 1.80), and symptom/diagnostic remission (RR = 2.06). Greater methodological quality was associated with a lower treatment response for SRI trials. The NNT was five for treatment response and symptom/diagnostic remission. 

**Conclusions **
Findings demonstrate the treatment effects for CBT and SRIs across three important outcome metrics, and provide evidence for moderators of CBT across trials. 

Copyright &copy; 2015 Wiley Periodicals, Inc.
AN  - 605068105
AU  - McGuire,
AU  - J.
AU  - F.
AU  - Piacentini,
AU  - J.
AU  - Lewin,
AU  - A.
AU  - B.
AU  - Brennan,
AU  - E.
AU  - A.
AU  - Murphy,
AU  - T.
AU  - K.
AU  - Storch,
AU  - E.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/da.22389
L1  - internal-pdf://3430272915/McGuire-2015-A META-ANALYSIS of COGNITIVE BEHA.pdf
PY  - 2015
SP  - 580-593
TI  - A meta-analysis of cognitive behavior therapy and medication for child obsessive-compulsive disorder: Moderators of treatment efficacy, response, and remission
UR  - http://www.interscience.wiley.com/jpages/1091-4269
VL  - 32
ER  -
TY  - JOUR
AB  - Systemic therapy is a frequently used form of psychotherapy for the treatment of mental disorders in children and adolescents. The present study reports the results of the first meta-analysis on the effects of systemic treatment of mental disorders and behavior problems in children and adolescents. 

Based on systematic search in electronic databases (PsycINFO, Psyndex, PubMed, ISI Web of Knowledge, CINAHL), k=56 randomized, controlled trials met the inclusion criteria. We computed a random-effects meta-analysis. 

Systemic therapy showed small-to-medium effects in comparison with an untreated control group (posttest: k=7, g=.59 standard deviation units, follow-up: k=2, g=.27) and alternative treatment (posttest: k=43, g=.32, follow-up: k=38, g=.28). At follow-up, longer interventions produced larger effect sizes. No other moderator effects were identified. 

Although available randomized, controlled trials show convincing results, their effects refer to a limited number of systemic approaches and mental disorders, and also pertain to adolescents rather than younger children. Thus, more research is needed before more general conclusions about the effects of systemic therapy can be drawn.
AD  - Riedinger, Verena. a Department of Psychology , Philipps University. Pinquart, Martin. a Department of Psychology , Philipps University. Teubert, Daniela. a Department of Psychology , Philipps University.
AN  - 26467300
AU  - Riedinger,
AU  - V.
AU  - Pinquart,
AU  - M.
AU  - Teubert,
AU  - D.
DA  - Oct 14
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/15374416.2015.1063427
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
L1  - internal-pdf://1120250341/Effects of Systemic Therapy on Mental Health o.pdf
LA  - English
N1  - Riedinger, Verena Pinquart, Martin Teubert, Daniela
PY  - 2015
SP  - 1-15
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Effects of Systemic Therapy on Mental Health of Children and Adolescents: A Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=26467300http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26467300&amp;id=doi:10.1080%2F15374416.2015.1063427&amp;issn=1537-4416&amp;isbn=&amp;volume=&amp;issue=&amp;spage=1&amp;pages=1-15&amp;date=2015&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Effects+of+Systemic+Therapy+on+Mental+Health+of+Children+and+Adolescents%3A+A+Meta-Analysis.&amp;aulast=Riedinger&amp;pid=%3Cauthor%3ERiedinger+V%3C%2Fauthor%3E%3CAN%3E26467300%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
ER  -
TY  - JOUR
AB  - **Background**
Feeding difficulties are relatively common in children with autism spectrum disorders (ASD), but current evidence for their treatment is limited. This review systematically identifies, reviews and analyses the evidence for intervention in young children with ASD and feeding difficulties. 

**Methods**
A comprehensive search strategy was used to identify studies from January 2000 to October 2013. Studies were included if they described interventions where the goal was to increase desirable eating behaviours or decrease undesirable eating behaviours using an experimental design, including single-subject research methodology. Studies were reviewed for descriptive information, and research quality was appraised using a formal checklist. Individual study findings were compared using Improvement Rate Difference (IRD), a method for calculating effect size in single-subject research. 

**Results**
Overall, 23 papers were included. All studies reviewed had five or fewer participants, and reported on operant conditioning style intervention approaches, where the child is prompted to perform an action, and receives a contingent response. Where quality measures were not met, it was primarily due to lack of detail provided for the purposes of replication, or failure to meet social validity criteria. Meta-analysis indicated a medium-large effect size [mean = 0.69, 95% confidence interval (CI) 0.60 to 0.79] when the outcome measured was an increase in desirable behaviours (e.g. consuming food), but a small-negligible effect size (mean = 0.39, 95% CI 0.18 to 0.60) when the outcome measured was a decrease in undesirable mealtime behaviours (e.g. tantrums). Only a small proportion of studies reported outcomes in terms of increased dietary variety rather than volume of food consumed. 

**Conclusions**
The reviewed literature consisted primarily of low-level evidence. Favourable intervention outcomes were observed in terms of increasing volume, but not necessarily variety of foods consumed in young children with ASD and feeding difficulties. Further research in the form of prospective randomized trials to further demonstrate experimental effect in this area is required.
AD  - [Marshall, J.; Hill, R. J.] Univ Queensland, Queensland Childrens Med Res Inst, Childrens Nutr Res Ctr, Brisbane, Qld, Australia. [Ware, R.; Ziviani, J.] Univ Queensland, Queensland Childrens Med Res Inst, Brisbane, Qld, Australia. [Ware, R.] Univ Queensland, Queensland Ctr Intellectual &amp; Dev Disabil, Brisbane, Qld, Australia. [Ziviani, J.] Univ Queensland, Sch Hlth &amp; Rehabil Sci, Brisbane, Qld, Australia. [Ziviani, J.; Dodrill, P.] Royal Childrens Hosp, Childrens Hlth Queensland, Brisbane, Qld 4029, Australia. Marshall, J (reprint author), Royal Childrens Hosp, Queensland Childrens Med Res Inst, Level 4,Fdn Bldg,Herston Rd, Brisbane, Qld 4029, Australia. j.marshall@uq.edu.au
AN  - WOS:000349771100013
AU  - Marshall,
AU  - J.
AU  - Ware,
AU  - R.
AU  - Ziviani,
AU  - J.
AU  - Hill,
AU  - R.
AU  - J.
AU  - Dodrill,
AU  - P.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/cch.12157
J2  - Child Care Health Dev.
KW  - autism spectrum disorder eating feeding difficulties feeding disorders interventions treatment TREAT FOOD SELECTIVITY SINGLE-CASE-RESEARCH ESCAPE EXTINCTION NONCONTINGENT REINFORCEMENT DIFFERENTIAL REINFORCEMENT YOUNG-CHILD INCREASE DISABILITIES CAREGIV
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CB6XU Times Cited: 0 Cited Reference Count: 56 Marshall, J. Ware, R. Ziviani, J. Hill, R. J. Dodrill, P. WILEY-BLACKWELL HOBOKEN CHILD CARE HLTH DEV
PY  - 2015
SP  - 278-302
T2  - Child Care Health and Development
TI  - Efficacy of interventions to improve feeding difficulties in children with autism spectrum disorders: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000349771100013http://onlinelibrary.wiley.com/store/10.1111/cch.12157/asset/cch12157.pdf?v=1&amp;t=ib7nmrxl&amp;s=de6ac998567eb9e1fc8301236ff81f575932f9da
VL  - 41
ER  -
TY  - JOUR
AB  - **Background:** 
Self-harm (SH; intentional self-poisoning or self-injury) is common in children and adolescents, often repeated, and strongly associated with suicide. This is an update of a broader Cochrane review on psychosocial and pharmacological treatments for deliberate SH first published in 1998 and previously updated in 1999. We have now divided the review into three separate reviews; this review is focused on psychosocial and pharmacological interventions for SH in children and adolescents.

**Objectives:** 
To identify all randomised controlled trials of psychosocial interventions, pharmacological agents, or natural products for SH in children and adolescents, and to conduct meta-analyses (where possible) to compare the effects of specific treatments with comparison types of treatment (e.g., treatment as usual (TAU), placebo, or alternative pharmacological treatment) for children and adolescents who SH.

**Search methods:** 
For this update the Cochrane Depression, Anxiety and Neurosis Group (CCDAN) Trials Search Co-ordinator searched the CCDAN Specialised Register (30 January 2015).

**Selection criteria:** 
We included randomised controlled trials comparing psychosocial or pharmacological treatments with treatment as usual, alternative treatments, or placebo or alternative pharmacological treatment in children and adolescents (up to 18 years of age) with a recent (within six months) episode of SH resulting in presentation to clinical services.

**Data collection and analysis:** 
Two reviewers independently selected trials, extracted data, and appraised study quality, with consensus. For binary outcomes, we calculated odds ratios (OR) and their 95% confidence intervals (CI). For continuous outcomes measured using the same scale we calculated the mean difference (MD) and 95% CI; for those measured using different scales we calculated the standard mean difference (SMD) and 95% CI. Meta-analysis was only possible for two interventions: dialectical behaviour therapy for adolescents and group-based psychotherapy. For these analyses, we pooled data using a random-effects model.

**Main results:** 
We included 11 trials, with a total of 1,126 participants. The majority of participants were female (mean = 80.6% in 10 trials reporting gender). All trials were of psychosocial interventions; there were none of pharmacological treatments. With the exception of dialectical behaviour therapy for adolescents (DBT-A) and group-based therapy, assessments of specific interventions were based on single trials. We downgraded the quality of evidence owing to risk of bias or imprecision for many outcomes.Therapeutic assessment appeared to increase adherence with subsequent treatment compared with TAU (i.e., standard assessment; n = 70; k = 1; OR = 5.12, 95% CI 1.70 to 15.39), but this had no apparent impact on repetition of SH at either 12 (n = 69; k = 1; OR 0.75, 95% CI 0.18 to 3.06; GRADE: low quality) or 24 months (n = 69; k = 1; OR = 0.69, 05% CI 0.23 to 2.14; GRADE: low quality evidence). These results are based on a single cluster randomised trial, which may overestimate the effectiveness of the intervention.For patients with multiple episodes of SH or emerging personality problems, mentalisation therapy was associated with fewer adolescents scoring above the cut-off for repetition of SH based on the Risk-Taking and Self-Harm Inventory 12 months post-intervention (n = 71; k = 1; OR = 0.26, 95% CI 0.09 to 0.78; GRADE: moderate quality). DBT-A was not associated with a reduction in the proportion of adolescents repeating SH when compared to either TAU or enhanced usual care (n = 104; k = 2; OR 0.72, 95% CI 0.12 to 4.40; GRADE: low quality). In the latter trial, however, the authors reported a significantly greater reduction over time in frequency of repeated SH in adolescents in the DBT condition, in whom there were also significantly greater reductions in depression, hopelessness, and suicidal ideation.We found no significant treatment effects for group-based therapy on repetition of SH for individuals with multiple episodes of SH at either the six (n = 430; k = 2; OR 1.72, 95% CI 0.56 to 5.24; GRADE: low quality) or 12 month (n = 490; k = 3; OR 0.80, 95% CI 0.22 to 2.97; GRADE: low quality) assessments, although considerable heterogeneity was associated with both (I2 = 65% and 77% respectively). We also found no significant differences between the following treatments and TAU in terms of reduced repetition of SH: compliance enhancement (three month follow-up assessment: n = 63; k = 1; OR = 0.67, 95% CI 0.15 to 3.08; GRADE: very low quality), CBT-based psychotherapy (six month follow-up assessment: n = 39; k = 1; OR = 1.88, 95% CI 0.30 to 11.73; GRADE: very low quality), home-based family intervention (six month follow-up assessment: n = 149; k = 1; OR = 1.02, 95% CI 0.41 to 2.51; GRADE: low quality), and provision of an emergency card (12 month follow-up assessment: n = 105, k = 1; OR = 0.50, 95% CI 0.12 to 2.04; GRADE: very low quality). No data on adverse effects, other than the planned outcomes relating to suicidal behaviour, were reported.

**Authors&#039; conclusions:** 
There are relatively few trials of interventions for children and adolescents who have engaged in SH, and only single trials contributed to all but two comparisons in this review. The quality of evidence according to GRADE criteria was mostly very low. There is little support for the effectiveness of group-based psychotherapy for adolescents with multiple episodes of SH based on the results of three trials, the evidence from which was of very low quality according to GRADE criteria. Results for therapeutic assessment, mentalisation, and dialectical behaviour therapy indicated that these approaches warrant further evaluation. Despite the scale of the problem of SH in children and adolescents there is a paucity of evidence of effective interventions. Further large-scale trials, with a range of outcome measures including adverse events, and investigation of therapeutic mechanisms underpinning these interventions, are required. It is increasingly apparent that development of new interventions should be done in collaboration with patients to ensure that these are likely to meet their needs. Use of an agreed set of outcome measures would assist evaluation and both comparison and meta-analysis of trials.
AN  - CD012013
AU  - Hawton,
AU  - K.
AU  - Witt,
AU  - K.
AU  - G.
AU  - Taylor
AU  - Salisbury,
AU  - T.
AU  - L.
AU  - Arensman,
AU  - E.
AU  - Gunnell,
AU  - D.
AU  - Townsend,
AU  - E.
AU  - van
AU  - Heeringen,
AU  - K.
AU  - Hazell,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd012013
KW  - Anti-Anxiety Agents [therapeutic use]
KW  - Antidepressive Agents [therapeutic use]
KW  - Antipsychotic Agents [therapeutic use]
KW  - Behavior Therapy [methods]
KW  - Family Therapy
KW  - Patient Compliance [statistics &amp; numerical data]
KW  - Problem Solving
KW  - Psychotherapy [methods]
KW  - Psychotherapy, Group
KW  - Randomized Controlled Trials as Topic
KW  - Recurrence
KW  - Secondary Prevention [methods]
KW  - Self-Injurious Behavior [prevention &amp; control] [psychology]
KW  - Suicide [prevention &amp; control]
KW  - Theory of Mind
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Depressn
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for self-harm in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD012013/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD012013/asset/CD012013.pdf?v=1&amp;t=iw7jvjxp&amp;s=6a63d11d932fc3e6592a9e907ee17e930686f78c
ER  -
TY  - JOUR
AB  - **Background : **
bullying (and cyberbullying) is a widespread phenomenon among young people and it is used to describe interpersonal relationships characterized by an imbalance of power. In this relationships often show aggressive behavior and intentional &quot;harm doing&quot; repeated over time. The prevalence of bullying among youth has been reported to vary widely among countries (5.1%-41.4%) and this behavior seems generally higher among student boys than girls. Several school interventions have been developed to reduce bullying, but reported inconsistent results possibly related to limitations in the study design or to other methodological shortcomings. 

**Aims :**
evaluating randomized-controlled trials (RTCs) conducted between 2000 and 2013 to assess the effectiveness of school interventions on bullying and cyberbullying. 

**Methods : **
a systematic search of the scientific literature was conducted on Pubmed/Medline and Ebsco online databases. We also contacted experts in the field of preventive bullying research. 

**Results : **
17 studies met the inclusion criteria. The majority of studies did not show positive effects in the long term; the interventions focused on the whole school were more effective in reducing bullying than interventions delivered through classroom curricula or social skills training alone. 

**Conclusion : **
while there is evidence that programs aimed at reducing bullying can be effective in the short term, their long-term effectiveness has not been established, and there are important differences in the results based on gender, age and socio-economic status of participants. Internal inconsistency in the findings of some studies, together with the wide variability of experimental designs and lack of common standardized measures in outcome evaluation, are important limitations in this field of research.
AD  - Cantone, Elisa. Department of Public Health and Clinical and Molecular Medicine, University of Cagliari, Italy. Piras, Anna P. Department of Public Health and Clinical and Molecular Medicine, University of Cagliari, Italy. Vellante, Marcello. Department of Public Health and Clinical and Molecular Medicine, University of Cagliari, Italy. Preti, Antonello. Department of Public Health and Clinical and Molecular Medicine, University of Cagliari, Italy. Danielsdottir, Sigrun. Directorate of Health Baronsstig 47, IS-105 Reykjavik, Iceland. D&#039;Aloja, Ernesto. Department of Public Health and Clinical and Molecular Medicine, University of Cagliari, Italy. Lesinskiene, Sigita. Vilnius University, Clinic of Psychiatry, Faculty of Medicine, Vilnius, Lithuania. Angermeyer, Mathhias C. Department of Public Health and Clinical and Molecular Medicine, University of Cagliari, Italy ; Center for Public Mental Health, Gosim Austria. Carta, Mauro G. Directorate of Health Baronsstig 47, IS-105 Reykjavik, Iceland. Bhugra, Dinesh. Institute of Psychiatry (KCL), DeCrespigny Park, London, United Kingdom.
AN  - 25834628
AU  - Cantone,
AU  - E.
AU  - Piras,
AU  - A.
AU  - P.
AU  - Vellante,
AU  - M.
AU  - Preti,
AU  - A.
AU  - Danielsdottir,
AU  - S.
AU  - D&#039;Aloja,
AU  - E.
AU  - Lesinskiene,
AU  - S.
AU  - Angermeyer,
AU  - M.
AU  - C.
AU  - Carta,
AU  - M.
AU  - G.
AU  - Bhugra,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2174/1745017901511010058
DP  - Ovid Technologies
J2  - Clin Pract Epidemol Ment Health
L1  - internal-pdf://3207767538/Cantone-2015-Interventions on bullying and cyb.pdf
LA  - English
N1  - Cantone, Elisa Piras, Anna P Vellante, Marcello Preti, Antonello Danielsdottir, Sigrun D&#039;Aloja, Ernesto Lesinskiene, Sigita Angermeyer, Mathhias C Carta, Mauro G Bhugra, Dinesh CPEMH-11-58
PY  - 2015
SP  - 58-76
T2  - Clinical Practice and Epidemiology in Mental Health
TI  - Interventions on bullying and cyberbullying in schools: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25834628http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25834628&amp;id=doi:10.2174%2F1745017901511010058&amp;issn=1745-0179&amp;isbn=&amp;volume=11&amp;issue=1&amp;spage=58&amp;pages=58-76&amp;date=2015&amp;title=Clinical+Practice+%26+Epidemiology+in+Mental+Health+%5BElectronic+Resource%5D%3A+CP+%26+EMH&amp;atitle=Interventions+on+bullying+and+cyberbullying+in+schools%3A+a+systematic+review.&amp;aulast=Cantone&amp;pid=%3Cauthor%3ECantone+E%3C%2Fauthor%3E%3CAN%3E25834628%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378064/pdf/CPEMH-11-58.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - This systematic review examines the meta-analytic evidence on four broad categories of preventive interventions for children and adolescents, including: mentoring, service learning, outdoor adventure, and social and emotional learning (SEL) programs. 

There were 15 meta-analytic studies that fit the criteria for inclusion. For each intervention type, the target population, main implementation strategies, and meta-analytic evidence are reported. 

The review considers the effectiveness of these preventive interventions across various content areas and populations, providing an indication of which type of intervention has the strongest effects on what outcomes, where they are most beneficial, and for whom they are most promising. 

Experimental evidence has demonstrated that mentoring, service learning, outdoor adventure, and SEL programs can all promote positive development and prevent problematic behaviors. 

Overall, service learning, outdoor adventure, and SEL programs have shown small to large effects on a variety of outcomes, while mentoring has shown small but significant effects. 

The review concludes with a discussion of key criteria that should be considered when choosing a particular program type. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Gutman, Leslie Morrison: l.gutman@ioe.ac.uk Gutman, Leslie Morrison: Department of Quantitative Social Science, University College London Institute of Education, 20 Bedford Way, London, United Kingdom, WC1H 0AL, l.gutman@ioe.ac.uk Gutman, Leslie Morrison: University College London Institute of Education, University College London, London, United Kingdom Schoon, Ingrid: University College London Institute of Education, University College London, London, United Kingdom
AN  - 2015-48598-001
AU  - Gutman,
AU  - L.
AU  - M.
AU  - Schoon,
AU  - I.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1027/1016-9040/a00023
DP  - Ovid Technologies
KW  - mentoring, service learning, outdoor adventure, social and emotional learning (SEL), children and adolescents
KW  - *Intervention
KW  - *Mentor
KW  - *Prevention
KW  - *Service Learning
KW  - *Wilderness Experience
KW  - Emotions
KW  - Social Learning
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human Male Female Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://2130965787/231.pdf
LA  - English
M3  - Literature Review
PY  - 2015
SP  - 231-241
T2  - European Psychologist
TI  - Preventive interventions for children and adolescents: A review of meta-analytic evidence
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-48598-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1027%2F1016-9040%2Fa000232&amp;issn=1016-9040&amp;isbn=&amp;volume=20&amp;issue=4&amp;spage=231&amp;pages=231-241&amp;date=2015&amp;title=European+Psychologist&amp;atitle=Preventive+interventions+for+children+and+adolescents%3A+A+review+of+meta-analytic+evidence.&amp;aulast=Gutman&amp;pid=%3Cauthor%3EGutman%2C+Leslie+Morrison%3C%2Fauthor%3E%3CAN%3E2015-48598-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 20
ER  -
TY  - JOUR
AB  - The purpose of this review was to critically examine and summarize the impact of school-based interventions designed to facilitate the peer-related social competence of children with autism spectrum disorder (ASD). 

Reviewed studies employed a single-case experimental design, targeted peer-related social competence, included children 3-12 years old with an ASD, and took place in school settings. 

Articles were analyzed descriptively and using the evaluative method to determine study quality. 

Additionally, effect size estimates were calculated using nonoverlap of all pairs method and Tau-U. A total of 37 studies including 105 children were reviewed. 

Overall, ES estimates ranged from weak to strong, but on average, the reviewed interventions produced a moderate to strong effect, and quality ratings were generally in the acceptable to high range. 

Findings suggest that children with ASD can benefit from social skill interventions implemented with peers in school settings. 

(PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract).
AD  - Whalon, Kelly J.: kwhalon@fsu.edu; Conroy, Maureen A.: mconroy@coe.ufl.edu; Martinez, Jose R.: j.martinez36@gmail.com; Werch, Brittany L.: blwerch@gmail.com Whalon, Kelly J.: College of Education, Florida State University, P.O. Box 3064450, 1114 W. Call Street, Tallahassee, FL, US, 32306-4450, kwhalon@fsu.edu Whalon, Kelly J.: College of Education, Florida State University, Tallahassee, FL, US Conroy, Maureen A.: College of Education, University of Florida, Tallahassee, FL, US Martinez, Jose R.: College of Education, University of Florida, Tallahassee, FL, US Werch, Brittany L.: College of Education, University of Florida, Tallahassee, FL, US
AN  - 2015-05042-001
AU  - Whalon,
AU  - K.
AU  - J.
AU  - Conroy,
AU  - M.
AU  - A.
AU  - Martinez,
AU  - J.
AU  - R.
AU  - Werch,
AU  - B.
AU  - L.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10803-015-2373-1
DP  - Ovid Technologies
KW  - Social competence, Social communication, Autism spectrum disorder, Literature review, Meta-analysis Psychological &amp; Physical Disorders [3200]
PY  - 2015
SP  - No Pagination Specified
T2  - Journal of Autism and Developmental Disorders
TI  - School-based peer-related social competence interventions for children with autism spectrum disorder: A meta-analysis and descriptive review of single case research design studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2015-05042-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10803-015-2373-1&amp;issn=0162-3257&amp;isbn=&amp;volume=&amp;issue=&amp;spage=No&amp;pages=No+Pagination+Specified&amp;date=2015&amp;title=Journal+of+Autism+and+Developmental+Disorders&amp;atitle=School-based+peer-related+social+competence+interventions+for+children+with+autism+spectrum+disorder%3A+A+meta-analysis+and+descriptive+review+of+single+case+research+design+studies.&amp;aulast=Whalon&amp;pid=%3Cauthor%3EWhalon%2C+Kelly+J%3C%2Fauthor%3E%3CAN%3E2015-05042-001%3C%2FAN%3E%3CDT%3E%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10803-015-2373-1http://download.springer.com/static/pdf/700/art%253A10.1007%252Fs10803-015-2373-1.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10803-015-2373-1&amp;token2=exp=1435232073~acl=%2Fstatic%2Fpdf%2F700%2Fart%25253A10.1007%25252Fs10803-015-2373-1.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10803-015-2373-1*~hmac=07ec7010e3f3885011d26d55f18524b64b54e151a0f25d9ce96af7e2461934b2
ER  -
TY  - JOUR
AB  - Early secure maternal-child attachment relationships lay the foundation for children&#039;s healthy social and mental development. Interventions targeting maternal sensitivity and maternal reflective function during the first year of infant life may be the key to promoting secure attachment. 

We conducted a narrative systematic review and meta-analysis to examine the effectiveness of interventions aimed at promoting maternal sensitivity and reflective function on maternal-child attachment security, as measured by the gold standard Strange Situation (M. Ainsworth, M. Blehar, B. Waters, &amp; S. Wall, 1978) and Q-set (E. Waters &amp; K. Deane, 1985). Studies were identified from electronic database searches and included randomized or quasi-randomized controlled parallel-group designs. 

Participants were mothers and their infants who were followed up to 36 months&#039; postpartum. Ten trials, involving 1,628 mother-infant pairs, were included. Examination of the trials that provided sufficient data for combination in meta-analysis revealed that interventions of both types increased the odds of secure maternal-child attachment, as compared with no intervention or standard intervention (n = 7 trials; odds ratio: 2.77; 95% confidence interval: 1.69, 4.53, n = 965). 

Of the three trials not included in the meta-analyses, two improved the likelihood of secure attachment. We conclude that interventions aimed at improving maternal sensitivity alone or in combination with maternal reflection, implemented in the first year of infants&#039; lives, are effective in promoting secure maternal-child attachments. Intervention aimed at the highest risk families produced the most beneficial effects. 

Copyright &copy; 2015 Michigan Association for Infant Mental Health.
AD  - Letourneau, Nicole. Alberta Children&#039;s Hospital Research Institute for Child and Maternal Health, University of Calgary. Tryphonopoulos, Panagiota. University of New Brunswick, Fredericton. Giesbrecht, Gerald. Alberta Children&#039;s Hospital. Dennis, Cindy-Lee. University of Toronto. Bhogal, Sanjit. University of Calgary. Watson, Barry. University of New Brunswick, Fredericton.
AN  - 26112776
AU  - Letourneau,
AU  - N.
AU  - Tryphonopoulos,
AU  - P.
AU  - Giesbrecht,
AU  - G.
AU  - Dennis,
AU  - C.
AU  - L.
AU  - Bhogal,
AU  - S.
AU  - Watson,
AU  - B.
DA  - Jul-Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/imhj.21525
DP  - Ovid Technologies
J2  - Infant Ment Health J
KW  - Child, Preschool
KW  - Female
KW  - Humans
KW  - Infant
KW  - *Maternal Behavior/px [Psychology]
KW  - *Mother-Child Relations/px [Psychology]
KW  - *Mothers/px [Psychology]
KW  - *Object Attachment
KW  - *Parenting/px [Psychology]
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://2290891002/Letourneau-2015-Narrative and Meta-Analytic Re.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Letourneau, Nicole Tryphonopoulos, Panagiota Giesbrecht, Gerald Dennis, Cindy-Lee Bhogal, Sanjit Watson, Barry
PY  - 2015
SP  - 366-87
T2  - Infant Mental Health Journal
TI  - Narrative and Meta-Analytic Review of Interventions Aiming to Improve Maternal-Child Attachment Security
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26112776http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26112776&amp;id=doi:10.1002%2Fimhj.21525&amp;issn=0163-9641&amp;isbn=&amp;volume=36&amp;issue=4&amp;spage=366&amp;pages=366-87&amp;date=2015&amp;title=Infant+Mental+Health+Journal&amp;atitle=NARRATIVE+AND+META-ANALYTIC+REVIEW+OF+INTERVENTIONS+AIMING+TO+IMPROVE+MATERNAL-CHILD+ATTACHMENT+SECURITY.&amp;aulast=Letourneau&amp;pid=%3Cauthor%3ELetourneau+N%3C%2Fauthor%3E%3CAN%3E26112776%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1002/imhj.21525/asset/imhj21525.pdf?v=1&amp;t=j02f5lry&amp;s=9094b2fc9e07c5f312ccfe1424ce0ee69cd8b359
VL  - 36
ER  -
TY  - JOUR
AB  - **Slutsatser**
Inget av de manualbaserade programmen f&ouml;r skolan har visats fungera allm&auml;nt drogf&ouml;rebyggande. Enstaka program har visats kunna minska konsumtion av tobak eller cannabis eller tungt episodiskt drickande. Effekterna &auml;r vanligen i storleksordningen 1&ndash;5 procent. Det vetenskapliga st&ouml;det r&auml;cker inte f&ouml;r att dra några slutsatser om effekten av manual&shy;baserade f&ouml;r&auml;ldrast&ouml;dsprogram i grupp. Skol- och f&ouml;r&auml;ldra&shy;st&ouml;dsprogram har i några studier lett till &ouml;kad konsumtion.

Så kallade multimodala projekt, det vill s&auml;ga projekt d&auml;r olika akt&ouml;rer i lokalsamh&auml;llet agerar gemensamt och d&auml;r flera tillg&auml;nglighets&shy;begr&auml;nsande insatser ingår, kan minska konsumtionen av alkohol hos unga. En f&ouml;ruts&auml;ttning &auml;r att insatserna implementeras v&auml;l. Projekt i lokalsamh&auml;llet d&auml;r akt&ouml;rerna i huvud&shy;sak v&auml;ljer och samordnar olika efterfråge&shy;begr&auml;nsande insatser har inga eller mycket små effekter på konsumtion av alkohol, cannabis och tobak.

Kortvariga insatser i form av motiverande samtal och så kallad personanpassad normativ återkoppling kan minska alkoholkonsumtion hos unga med riskbruk.

SBU:s h&auml;lsoekonomiska analys &ouml;ver alko&shy;hol&shy;preventivt arbete skattar att två f&ouml;rebyggande insatser skulle kunna ge måttliga kostnader per h&auml;lsoeffekt. F&ouml;rutsatt att andelen ungdomar som intensivkonsumerar minskar med minst 5 procent, skulle ett specifikt skolbaserat program kunna vara kostnads&shy;effektivt. Motiverande samtal skulle kunna vara kostnadseffektivt om andelen ungdomar som intensivkonsumerade minskar med minst 2,5 procent.

Trots att litteraturen &auml;r omfattande om missbruksprevention finns det stora kunskapsluckor. Nya interventioner som bygger på andra teorier &auml;n de utv&auml;rderade manualbaserade programmen beh&ouml;ver utvecklas och utv&auml;rderas i studier med adekvat design. Ytterligare forskning beh&ouml;vs &auml;ven avseende interventioner riktade till unga vuxna utanf&ouml;r skol- och h&ouml;g&shy;skolemilj&ouml;, liksom insatser som syftar till att f&ouml;rebygga missbruk av dopningspreparat, l&auml;kemedel och spel.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /sv/publikationer/SBU-utvarderar/att-forebygga-missbruk-av-alkohol-droger-och-spel-hos-barn-och-unga/
L1  - internal-pdf://2543500529/forebygga_missbruk_alkohol_droger_spel_barn_un.pdf
PY  - 2015
TI  - Att f&ouml;rebygga missbruk av alkohol, droger och spel hos barn och unga.
ER  -
TY  - JOUR
AB  - Maladaptive aggression in adolescents is an increasing public health concern. Cognitive Behavior Therapy (CBT) is one of the most common and promising treatments of aggression. However, there is a lack of information on predictors of treatment response regarding CBT. Therefore, a meta-analysis was performed examining the role of predictors on treatment response of CBT. Twenty-five studies were evaluated (including 2,302 participants; 1,580 boys and 722 girls), and retrieved through searches on PubMed, PsycINFO and EMBASE. 

Effect sizes were calculated for studies that met inclusion criteria. Study population differences and specific CBT characteristics were examined for their explanatory power. There was substantial variation across studies in design and outcome variables. The meta-analysis showed a medium treatment effect for CBT to reduce aggression (Cohen&#039;d = 0.50). No predictors of treatment response were found in the meta-analysis. Only two studies did examine whether proactive versus reactive aggression could be a moderator of treatment outcome, and no effect was found of this subtyping of aggression. 

These study results suggest that CBT is effective in reducing maladaptive aggression. Furthermore, treatment setting and duration did not seem to influence treatment effect, which shows the need for development of more cost-effective and less-invasive interventions. 

More research is needed on moderators of outcome of CBT, including proactive versus reactive aggression. This requires better standardization of design, predictors, and outcome measures across studies.
AD  - Smeets,Kirsten C. Karakter Child and Adolescent Psychiatry University Centre, Reinier Postlaan 12, 6525 GC, Nijmegen, The Netherlands, k.smeets@karakter.com.
AN  - 25138144
AU  - Smeets,
AU  - K.
AU  - C.
AU  - Leeijen,
AU  - A.
AU  - A.
AU  - van
AU  - der
AU  - Molen,
AU  - M.
AU  - J.
AU  - Scheepers,
AU  - F.
AU  - E.
AU  - Buitelaar,
AU  - J.
AU  - K.
AU  - Rommelse,
AU  - N.
AU  - N.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-014-0592-1
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
LA  - English
N1  - Smeets, Kirsten C Leeijen, Anouk A M van der Molen, Mariet J Scheepers, Floor E Buitelaar, Jan K Rommelse, Nanda N J
PY  - 2015
SP  - 255-64
T2  - European Child &amp; Adolescent Psychiatry
TI  - Treatment moderators of cognitive behavior therapy to reduce aggressive behavior: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25138144 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25138144&amp;id=doi:10.1007%2Fs00787-014-0592-1&amp;issn=1018-8827&amp;isbn=&amp;volume=24&amp;issue=3&amp;spage=255&amp;pages=255-64&amp;date=2015&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=Treatment+moderators+of+cognitive+behavior+therapy+to+reduce+aggressive+behavior%3A+a+meta-analysis.&amp;aulast=Smeets&amp;pid=%3Cauthor%3ESmeets+KC%3C%2Fauthor%3E%3CAN%3E25138144%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://download.springer.com/static/pdf/40/art%253A10.1007%252Fs00787-014-0592-1.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-014-0592-1&amp;token2=exp=1434977927~acl=%2Fstatic%2Fpdf%2F40%2Fart%25253A10.1007%25252Fs00787-014-0592-1.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-014-0592-1*~hmac=e68ea5f6413f9e8ec029f48d8d755699df70f4d84b08c33225f8f474d1dea6dc
VL  - 24
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Consistent findings about the effectiveness of parent programs to prevent or reduce child maltreatment are lacking. 

**METHODS: **
In the present meta-analysis we synthesized findings from 27 independent samples from randomized controlled trials (RCTs) on the effectiveness of 20 different intervention programs aimed at (i) preventing the occurrence of child maltreatment in the general population or with at-risk but non-maltreating families, or (ii) reducing the incidence of child maltreatment in maltreating families. 

**RESULTS: **
A significant combined effect on maltreatment (d = 0.13; N = 4883) disappeared after the trim-and-fill approach that takes into account publication bias against smaller studies without significant outcomes. However, moderator analyses showed that larger effect sizes were found for more recent studies, studies with smaller samples, programs that provide parent training instead of only support, programs that target maltreating instead of at-risk families, and programs with a moderate length (6-12 months) or a moderate number of sessions (16-30). 

**CONCLUSIONS:** 
More RCTs are needed to further unravel which factors are associated with program effectiveness. Because currently existing programs appeared to only reduce and not prevent child maltreatment, efforts in the field of preventive intervention should also focus on the development and testing of preventive programs for families at risk for child maltreatment.
AD  - Euser, Saskia. Centre for Child and Family Studies, Leiden University, P.O. Box 9555, 2300 RB, Leiden, Netherlands. s.euser@fsw.leidenuniv.nl. Alink, Lenneke Ra. Centre for Child and Family Studies, Leiden University, P.O. Box 9555, 2300 RB, Leiden, Netherlands. alinklra@fsw.leidenuniv.nl. Stoltenborgh, Marije. Centre for Child and Family Studies, Leiden University, P.O. Box 9555, 2300 RB, Leiden, Netherlands. stoltenborghmarije@gmail.com. Bakermans-Kranenburg, Marian J. Centre for Child and Family Studies, Leiden University, P.O. Box 9555, 2300 RB, Leiden, Netherlands. bakermans@fsw.leidenuniv.nl. van IJzendoorn, Marinus H. Centre for Child and Family Studies, Leiden University, P.O. Box 9555, 2300 RB, Leiden, Netherlands. vanijzen@fsw.leidenuniv.nl.
AN  - 26476980
AU  - Euser,
AU  - S.
AU  - Alink,
AU  - L.
AU  - R.
AU  - Stoltenborgh,
AU  - M.
AU  - Bakermans-Kranenburg,
AU  - M.
AU  - J.
AU  - van
AU  - IJzendoorn,
AU  - M.
AU  - H.
DA  - Oct 18
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/s12889-015-2387-9
DP  - Ovid Technologies
J2  - BMC Public Health
KW  - Child
KW  - *Child Abuse/pc [Prevention &amp; Control]
KW  - Humans
KW  - *Parents/ed [Education]
KW  - Program Evaluation
KW  - Randomized Controlled Trials as Topic
KW  - Time Factors
L1  - internal-pdf://0552328135/Euser-2015-A gloomy picture_ a meta-analysis o.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Euser, Saskia Alink, Lenneke Ra Stoltenborgh, Marije Bakermans-Kranenburg, Marian J van IJzendoorn, Marinus H 10.1186/s12889-015-2387-9
PY  - 2015
SP  - 1068
T2  - BMC Public Health
TI  - A gloomy picture: a meta-analysis of randomized controlled trials reveals disappointing effectiveness of programs aiming at preventing child maltreatment
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26476980http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26476980&amp;id=doi:10.1186%2Fs12889-015-2387-9&amp;issn=1471-2458&amp;isbn=&amp;volume=15&amp;issue=1&amp;spage=1068&amp;pages=1068&amp;date=2015&amp;title=BMC+Public+Health&amp;atitle=A+gloomy+picture%3A+a+meta-analysis+of+randomized+controlled+trials+reveals+disappointing+effectiveness+of+programs+aiming+at+preventing+child+maltreatment.&amp;aulast=Euser&amp;pid=%3Cauthor%3EEuser+S%3C%2Fauthor%3E%3CAN%3E26476980%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609474/pdf/12889_2015_Article_2387.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - In order to quantify the effectiveness of family interventions in preventing and reducing adolescent illicit drug use, we conducted a systematic review and meta-analysis of randomized controlled trials. We searched the Cochrane Database of Systematic Reviews, Educational Research Information Centre (ERIC), MEDLINE, Embase, and PsycINFO for studies published between 1995 and 2013. 

Results were described separately for different outcomes (marijuana vs. other illicit drugs) and intervention types (universal, selective, and indicated prevention). Meta-analyses were performed when data were sufficient (e.g., marijuana and other illicit drug initiation in universal samples), using random effect models. Otherwise, we provided narrative reviews (e.g., regarding selective and indicated prevention). Thirty-nine papers describing 22 RCTs were eligible for inclusion. 

Universal family interventions targeting parent-child dyads are likely to be effective in preventing (OR 0.72; 95 % CI 0.56, 0.94) and reducing adolescent marijuana use, but not in preventing other illicit drugs (OR 0.90; 95 % CI 0.60, 1.34). Among high-risk groups, there is no clear evidence for the effectiveness of family interventions in preventing and reducing illicit drug use and drug disorders. 

The three small RCTs among substance-(ab)using adolescents gave some indication that programs might reduce the frequency of illicit drug use. Family interventions targeting parent-child dyads are likely to be effective in preventing and reducing adolescent marijuana use in general populations, but no evidence for other illicit drug use was found. We underline the need to strengthen the evidence base with more trials, especially among at-risk populations.
AD  - [Vermeulen-Smit, Evelien; Verdurmen, J. E. E.; Engels, R. C. M. E.] Trimbos Inst, Netherlands Inst Mental Hlth &amp; Addict, Monitoring &amp; Epidemiol Dept, NL-3500 AS Utrecht, Netherlands. [Engels, R. C. M. E.] Radboud Univ Nijmegen, Inst Behav Sci, NL-6525 ED Nijmegen, Netherlands. Vermeulen-Smit, E (reprint author), Trimbos Inst, Netherlands Inst Mental Hlth &amp; Addict, Monitoring &amp; Epidemiol Dept, POB 725, NL-3500 AS Utrecht, Netherlands. evermeulen@trimbos.nl
AN  - WOS:000359641700002
AU  - Vermeulen-Smit,
AU  - E.
AU  - Verdurmen,
AU  - J.
AU  - E.
AU  - E.
AU  - Engels,
AU  - R.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10567-015-0185-7
J2  - Clin. Child Fam. Psychol. Rev.
KW  - Systematic review
KW  - Meta-analysis
KW  - Family intervention
KW  - Randomized
KW  - controlled trial
KW  - Adolescent
KW  - Drug use
KW  - substance use outcomes
KW  - mother-daughter program
KW  - hiv-affected families
KW  - cannabis use
KW  - centered intervention
KW  - follow-up
KW  - base-line
KW  - universal
KW  - intervention
KW  - abusing adolescents
KW  - risk behaviors
KW  - Psychology
L1  - internal-pdf://1005969666/Vermeulen-2015-The Effectiveness of Family Int.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: CP1NE Times Cited: 1 Cited Reference Count: 89 Vermeulen-Smit, Evelien Verdurmen, J. E. E. Engels, R. C. M. E. Dutch Organization for Health Research and Development [ZonMW: 50-51300-98-007] This work was granted by the Dutch Organization for Health Research and Development (ZonMW: 50-51300-98-007). 1 3 18 Springer/plenum publishers New york 1573-2827
PY  - 2015
SP  - 218-239
T2  - Clinical Child and Family Psychology Review
TI  - The Effectiveness of Family Interventions in Preventing Adolescent Illicit Drug Use: A Systematic Review and Meta-analysis of Randomized Controlled Trials
UR  - &lt;Go to ISI&gt;://WOS:000359641700002
UR  - https://link.springer.com/article/10.1007/s10567-015-0185-7
UR  - http://download.springer.com/static/pdf/374/art%253A10.1007%252Fs10567-015-0185-7.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10567-015-0185-7&amp;token2=exp=1489074097~acl=%2Fstatic%2Fpdf%2F374%2Fart%25253A10.1007%25252Fs10567-015-0185-7.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10567-015-0185-7*~hmac=84c82f7ff7146140ac8cfa399ea6af157bdbe27fe6eb72c2792609f6f54843bb
VL  - 18
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Randomized controlled trials have demonstrated that antidepressants are efficacious in the treatment of anxiety disorders in youth. However, there are no recent, systematic analyses of the efficacy, safety, or tolerability of these medications in pediatric anxiety disorders. 

**METHODS: **
A systematic review and meta-analysis of prospective, randomized, parallel-group, controlled trials of selective serotonin reuptake inhibitors (SSRIs) and selective serotonin-norepinephrine reuptake inhibitors (SSNRIs) in pediatric patients with non-obsessive compulsive disorder (OCD) anxiety disorders was undertaken using a search of PubMed/Medline (1966-2014). The meta-analysis utilized random-effects models to evaluate change in the Pediatric Anxiety Rating Scale or similar anxiety scale, suicidality, and adverse events. Additionally, pharmacologic variables were explored with regard to effect size, although no correction for multiple comparisons was made with regard to these relationships. 

**RESULTS: **
Nine trials involving 1,673 patients and six medications were included. All SSRI/SSNRIs evaluated demonstrated efficacy, and the meta-analytic estimate of effect was of moderate magnitude (Cohen&#039;s d = 0.62, confidence interval [CI]: 0.34-0.89, P = .009) and there was evidence of modest heterogeneity (I(2) = 0.29, P = .103). Activation trended toward being more likely with antidepressant treatment (OR: 1.86, CI: 0.98-3.53, P = .054), but no increased risk was observed for nausea/abdominal symptoms (P = .262), discontinuation as a result of an adverse event (P = .132), or suicidality (OR: 1.3, CI: 0.53-3.2, P = .514). Finally, the effect size correlated with the serotonergic specificity of the agent (R = .79, P = .021). 

**CONCLUSIONS: **
Data for nine SSRI/SSNRIs suggest superiority of antidepressants relative to placebo for the treatment of pediatric anxiety disorders with a moderate effect size. 

Copyright &copy; 2014 Wiley Periodicals, Inc.
AD  - Strawn, Jeffrey R. Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati, College of Medicine, Cincinnati, Ohio; Department of Psychiatry, Cincinnati Children&#039;s Hospital Medical Center, Cincinnati, Ohio.
AN  - 25449861
AU  - Strawn,
AU  - J.
AU  - R.
AU  - Welge,
AU  - J.
AU  - A.
AU  - Wehry,
AU  - A.
AU  - M.
AU  - Keeshin,
AU  - B.
AU  - Rynn,
AU  - M.
AU  - A.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pubmed/25449861
DP  - Ovid Technologies
J2  - Depress Anxiety
KW  - Adolescent
KW  - Antidepressive Agents/ae [Adverse Effects]
KW  - *Antidepressive Agents/tu [Therapeutic Use]
KW  - Anxiety/dt [Drug Therapy]
KW  - *Anxiety Disorders/dt [Drug Therapy]
KW  - Anxiety Disorders/px [Psychology]
KW  - Child
KW  - Humans
KW  - Prospective Studies
KW  - Psychiatric Status Rating Scales
KW  - Randomized Controlled Trials as Topic
KW  - Serotonin Uptake Inhibitors/ae [Adverse Effects]
KW  - *Serotonin Uptake Inhibitors/tu [Therapeutic Use]
KW  - Serotonin and Noradrenaline Reuptake Inhibitors/ae [Adverse Effects]
KW  - *Serotonin and Noradrenaline Reuptake Inhibitors/tu [Therapeutic Use]
KW  - Suicidal Ideation
KW  - 0 (Antidepressive Agents)
KW  - 0 (Serotonin Uptake Inhibitors)
KW  - 0 (Serotonin and Noradrenaline Reuptake Inhibitors)
L1  - internal-pdf://1462749649/Strawn-2015-Efficacy and tolerability of antid.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov&#039;t Review
N1  - Strawn, Jeffrey R Welge, Jeffrey A Wehry, Anna M Keeshin, Brooks Rynn, Moira A
PY  - 2015
SP  - 149-57
T2  - Depression and Anxiety
TI  - Efficacy and tolerability of antidepressants in pediatric anxiety disorders: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25449861http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25449861&amp;id=doi:10.1002%2Fda.22329&amp;issn=1091-4269&amp;isbn=&amp;volume=32&amp;issue=3&amp;spage=149&amp;pages=149-57&amp;date=2015&amp;title=Depression+%26+Anxiety&amp;atitle=Efficacy+and+tolerability+of+antidepressants+in+pediatric+anxiety+disorders%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Strawn&amp;pid=%3Cauthor%3EStrawn+JR%3C%2Fauthor%3E%3CAN%3E25449861%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1002/da.22329/asset/da22329.pdf?v=1&amp;t=j03msib9&amp;s=80ddc88fe4e41e81f83b7ce649d6b06950824ecb
VL  - 32
ER  -
TY  - JOUR
AB  - **Introduction. **
Yoga is a holistic system of varied mind-body practices that can be used to improve mental and physical health and it has been utilized in a variety of contexts and situations. Educators and schools are looking to include yoga as a cost-effective, evidence-based component of urgently needed wellness programs for their students. 

**Objectives. **
The primary goal of this study was to systematically examine the available literature for yoga interventions exclusively in school settings, exploring the evidence of yoga-based interventions on academic, cognitive, and psychosocial benefits. 

**Methods. **
An extensive search was conducted for studies published between 1980 and October 31, 2014 (PubMed, PsycInfo, Embase, ISI, and the Cochrane Library). Effect size analysis, through standardized mean difference and Hedges&#039;g, allowed for the comparison between experimental conditions. 

**Results and Conclusions. **
Nine randomized control trials met criteria for inclusion in this review. Effect size was found for mood indicators, tension and anxiety in the POMS scale, self-esteem, and memory when the yoga groups were compared to control. Future research requires greater standardization and suitability of yoga interventions for children.
AD  - Ferreira-Vorkapic, C. Department of Physiology, Laboratory of Neurophysiology, Federal University of Sergipe (UFS), Avenida Marechal Rondon, s/n, Jardim Rosa Elze, Sao Cristovao, 49100-000 Aracaju, SE, Brazil ; Department of Psychology, FASE \ UNESA, Aracaju, SE, Brazil ; Trika Research Center, Loei, Thailand. Feitoza, J M. Department of Psychology, FASE \ UNESA, Aracaju, SE, Brazil. Marchioro, M. Department of Physiology, Laboratory of Neurophysiology, Federal University of Sergipe (UFS), Avenida Marechal Rondon, s/n, Jardim Rosa Elze, Sao Cristovao, 49100-000 Aracaju, SE, Brazil. Simoes, J. Department of Physiology, Laboratory of Neurophysiology, Federal University of Sergipe (UFS), Avenida Marechal Rondon, s/n, Jardim Rosa Elze, Sao Cristovao, 49100-000 Aracaju, SE, Brazil. Kozasa, E. Hospital Israelita Albert Einstein, Sao Paulo, Brazil ; Department of Psychobiology, Federal University of Sao Paulo, Sao Paulo, Brazil. Telles, S. Indian Council of Medical Research Center for Advanced Research in Yoga and Patanjali Research Foundation, Bengaluru, India.
AN  - 26491461
AU  - Ferreira-Vorkapic,
AU  - C.
AU  - Feitoza,
AU  - J.
AU  - M.
AU  - Marchioro,
AU  - M.
AU  - Simoes,
AU  - J.
AU  - Kozasa,
AU  - E.
AU  - Telles,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1155/2015/345835
DP  - Ovid Technologies
J2  - Evid Based Complement Alternat Med
L1  - internal-pdf://3051217768/ECAM2015-345835.pdf
LA  - English
M3  - Review
N1  - Ferreira-Vorkapic, C Feitoza, J M Marchioro, M Simoes, J Kozasa, E Telles, S
PY  - 2015
SP  - 345835
T2  - Evidence-Based Complementary and Alternative Medicine
TI  - Are There Benefits from Teaching Yoga at Schools? A Systematic Review of Randomized Control Trials of Yoga-Based Interventions
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26491461http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26491461&amp;id=doi:10.1155%2F2015%2F345835&amp;issn=1741-427X&amp;isbn=&amp;volume=2015&amp;issue=&amp;spage=345835&amp;pages=345835&amp;date=2015&amp;title=Evidence-Based+Complementary+%26+Alternative+Medicine%3A+eCAM&amp;atitle=Are+There+Benefits+from+Teaching+Yoga+at+Schools%3F+A+Systematic+Review+of+Randomized+Control+Trials+of+Yoga-Based+Interventions.&amp;aulast=Ferreira-Vorkapic&amp;pid=%3Cauthor%3EFerreira-Vorkapic+C%3C%2Fauthor%3E%3CAN%3E26491461%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 2015
ER  -
TY  - JOUR
AB  - **Background:** 
A significant number of patients who suffer with anxiety and related disorders (that is post-traumatic stress disorder (PTSD), social anxiety disorder (SAnD), panic disorder with or without agoraphobia (PD), specific phobia (SPh) and obsessive compulsive disorder (OCD)) fail to respond optimally to first-line treatment with medication or cognitive and behavioural therapies. The addition of d-cycloserine (DCS) to cognitive and behavioural therapies may improve treatment response by impacting the glutamatergic system. This systematic review aimed to investigate the effects of adding DCS to cognitive and behavioural therapies by synthesising data from relevant randomised controlled trials and following the guidelines recommended by Cochrane.

**Objectives:** 
To assess the effect of DCS augmentation of cognitive and behavioural therapies compared to placebo augmentation of cognitive and behavioural therapies in the treatment of anxiety and related disorders. Additionally, to assess the efficacy and tolerability of DCS across different anxiety and related disorders.

**Search methods:** 
This review fully incorporates studies identified from a search of the Cochrane Depression, Anxiety and Neurosis Controlled Trials Register (CCDANCTR) to 12 March 2015. This register includes relevant randomised controlled trials (RCTs) from: the Cochrane Library (all years), EMBASE (1974 to date), MEDLINE (1950 to date), PsycINFO (1967 to date), the World Health Organization?s trials portal (ICTRP) and ClinicalTrials.gov . Reference lists from previous meta-analyses and reports of RCTs were also checked. No restrictions were placed on language, setting, date or publication status.

**Selection criteria:** 
All RCTs of DCS augmentation of cognitive and behavioural therapies versus placebo augmentation of cognitive and behavioural therapies for anxiety and related disorders were included.

**Data collection and analysis:** 
Two authors (RO and TA) independently assessed RCTs for eligibility and inclusion, extracted outcomes and risk of bias data and entered these into a customised extraction form. Investigators were contacted to obtain missing data. In addition, data entry and analysis were performed by two review authors (KSW and HB).

**Main results:** 
Twenty-one published RCTs, with 788 participants in outpatient settings, were included in the review. Sixteen studies had an age range of 18 to 75 years, while four investigated paediatric populations aged 8 to 17 years and one included children, adolescents and adults. The 21 RCTs investigated OCD (number of RCTs (N) = 6), PTSD (N = 5), SAnD (N = 5), SPh (N = 3) and PD (N = 2). Most information from the studies was rated as having either low risk or unclear risk of bias.There was no evidence of a difference between DCS augmentation of cognitive and behavioural therapies and placebo augmentation of cognitive and behavioural therapies for the treatment of anxiety and related disorders in adults at the endpoint (treatment responders, N = 9, risk ratio (RR) 1.10; 95% confidence interval (CI) 0.89 to 1.34; number of participants (n) = 449; low quality evidence) and between 1 and 12 months follow-up (N = 7, RR 1.08; 95% CI 0.90 to 1.31; n = 383). DCS augmentation of cognitive and behavioural therapies was not superior to placebo augmentation of cognitive and behavioural therapies for children and adolescents, both at the endpoint (N = 4, RR 1.01; 95% CI 0.78 to 1.31; n = 121; low quality evidence) and between 3 and 12 months follow-up (N = 3, RR 0.86; 95% CI 0.67 to 1.09; n = 91).There was no evidence of a difference in treatment acceptability for DCS augmentation of cognitive and behavioural therapies compared with placebo augmentation of cognitive and behavioural therapies in adults (N = 16, RR 0.88; 95% CI 0.61 to 1.25; n = 740), nor in children and adolescents (N = 4, RR 0.90; 95% CI 0.17 to 4.69; n = 131). These conclusions were based on moderate quality evidence for adults, and very low quality evidence for children and adolescents. Although the observed difference was small, it is noteworthy that there was a high efficacy of exposure-based therapies alone in the included trials. Due to the limited number of studies, subgroup analysis of moderating factors for clinical and methodological effect could not take place.

**Authors&#039; conclusions:** 
This review found no evidence of a difference between DCS augmentation of cognitive and behavioural therapies and placebo augmentation of cognitive and behavioural therapies for treating anxiety and related disorders in children, adolescents and adults. These findings are based on low quality evidence from heterogenous studies with small sample sizes and incomplete data for clinical response, which precludes us from drawing conclusions on the use of DCS augmentation of cognitive and behavioural therapies at this stage. Given there is some promising preliminary data from individual studies, further research is necessary to assess DCS compared with placebo augmentation of cognitive and behavioural therapies, and determine mechanisms of action as well as magnitude of effect in anxiety and related disorders.
AN  - CD007803
AU  - Ori,
AU  - R.
AU  - Amos,
AU  - T.
AU  - Bergman,
AU  - H.
AU  - Soares-Weiser,
AU  - K.
AU  - Ipser,
AU  - J.
AU  - C.
AU  - Stein,
AU  - D.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007803.pub2
KW  - Anxiety Disorders [therapy]
KW  - Cognitive Therapy [methods]
KW  - Combined Modality Therapy [methods]
KW  - Cycloserine [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Aged[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Middle Aged[checkword]
KW  - Depressn
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Augmentation of cognitive and behavioural therapies (CBT) with d-cycloserine for anxiety and related disorders
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007803.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007803.pub2/asset/CD007803.pdf?v=1&amp;t=iw7ivxg8&amp;s=2a6b0e0cd9c8a2bc4d593d91d14a1420ec8a9803
ER  -
TY  - JOUR
AB  - A meta-analysis of the single-case research examining the efficacy of Social StoryTM interventions for decreasing problem behaviours of children and adolescents with autism spectrum disorder was conducted by examining 27 outcome studies (n = 77) between 1995 and 2012 that yielded 64 intervention effects across three single-case outcome indicators. 

The overall mean visual analysis ratings and percentage of non-overlapping data scores indicated that the use of Social StoryTM interventions resulted in small to negligible effects whereas the weighted effect size estimator (ES = 0.79) indicated moderate to large treatment effects. 

Moderator analysis indicated that intervention setting, intervention agent, length of treatment, and publication status were all associated with positive effects for behavioural outcomes, although the significance of these outcomes were not consistent across indicators. Implications for practitioners and clinicians, suggestions for future research, and limitations are discussed. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - T McGill, Ryan J.: rmcgill@twu.edu McGill, Ryan J., rmcgill@twu.edu McGill, Ryan J.: Department of Psychology and Philosophy, Texas Woman&#039;s University, Denton, TX, US Baker, Diana: Department of School Counselling, Chapman University, Orange, CA, US Busse, R. T.: Department of School Counselling, Chapman University, Orange, CA, US
AN  - 2015-03798-002
AU  - McGill,
AU  - R.
AU  - J.
AU  - Baker,
AU  - D.
AU  - Busse,
AU  - R.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/02667363.2014.975785
DP  - Ovid Technologies
KW  - meta-analysis, single-case design, autism spectrum disorder, social story
KW  - *Autism Spectrum Disorders
KW  - *Behavior Problems
KW  - *School Based Intervention
KW  - Adolescent Development
KW  - Childhood Development
KW  - Educational/Vocational Counseling &amp; Student Services [3580]
KW  - Human
L1  - internal-pdf://1098740892/Social Story interventions for decreasing chal.pdf
LA  - English
M3  - Meta Analysis
PY  - 2015
SP  - 21-42
T2  - Educational Psychology in Practice
TI  - Social StoryTM interventions for decreasing challenging behaviours: A single-case meta-analysis 1995-2012
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-03798-002http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F02667363.2014.975785&amp;issn=0266-7363&amp;isbn=&amp;volume=31&amp;issue=1&amp;spage=21&amp;pages=21-42&amp;date=2015&amp;title=Educational+Psychology+in+Practice&amp;atitle=Social+StoryTM+interventions+for+decreasing+challenging+behaviours%3A+A+single-case+meta-analysis+1995-2012.&amp;aulast=McGill&amp;pid=%3Cauthor%3EMcGill%2C+Ryan+J%3C%2Fauthor%3E%3CAN%3E2015-03798-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 31
ER  -
TY  - JOUR
AB  - **Introduction: **
Creative bibliotherapy is the guided reading of fiction and poetry relevant to therapeutic needs. Experiencing stories is hypothesized to act on the same mechanisms as cognitive behavioral therapy (CBT). This systematic review assesses the efficacy and effectiveness of creative bibliotherapy for the prevention and treatment of internalizing and externalizing behaviors, and the strengthening of prosocial behaviors in children (aged 5-16). 

**Method: **
An electronic search in seven major databases was conducted along with hand searches of key journals and bibliographies. Only randomized or cluster-randomized trials were included. 

**Primary outcomes: **
internalizing behavior (e.g., anxiety and depression), externalizing behavior (e.g., aggression), and prosocial behavior (e.g., behavioral intentions and attitudes towards others). 

**Secondary outcomes:**
parent-child relationship, peer relationship, educational attainment and reading ability. 

**Results:** 
9180 records were located after removing duplicates. 9134 were excluded prior to screening. Of the 46 full-text articles assessed for eligibility, eight met the inclusion criteria and 38 were excluded. Meta-analysis was inappropriate due to study heterogeneity. Overall results suggest that creative bibliotherapy has small to moderate effect for internalizing behavior (delta range: 0.48-1.28), externalizing behavior (delta range: 0.53-1.09), and prosocial behavior (delta range: 0-1.2). 

**Conclusion: **
Creative bibliotherapy can have a small to moderate positive effect on child behavior. Although no definitive model of creative bibliotherapy emerges from the included studies, to some extent all interventions reflected CBT mechanisms. Further research is required to: 1) model the change processes taking place when children experience stories; 2) develop and pilot an intervention; 3) assess subgroup effects by gender, age, modality and literacy. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Montgomery, Paul: paul.montgomery@spi.ox.ac.uk; Maunders, Kathryn: k.maunders@gmail.com Maunders, Kathryn, k.maunders@gmail.com Montgomery, Paul: Centre for Evidence-Based Intervention, Department of Social Policy &amp; Intervention, University of Oxford, Oxford, United Kingdom Maunders, Kathryn: Centre for Evidence-Based Intervention, Department of Social Policy &amp; Intervention, University of Oxford, Oxford, United Kingdom
AN  - 2015-29712-006
AU  - Montgomery,
AU  - P.
AU  - Maunders,
AU  - K.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2015.05.010
DP  - Ovid Technologies
KW  - bibliotherapy, cognitive behavioral therapy, internalizing, externalizing, prosocial, children
KW  - *Bibliotherapy
KW  - *Cognitive Behavior Therapy
KW  - *Externalization
KW  - *Internalization
KW  - *Prosocial Behavior
KW  - Psychotherapy &amp; Psychotherapeutic Counseling [3310]
KW  - Human Childhood (birth-12 yrs)
L1  - internal-pdf://1875410934/Montgomery-2015-The effectiveness of creative.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2015
SP  - 37-47
T2  - Children and Youth Services Review
TI  - The effectiveness of creative bibliotherapy for internalizing, externalizing, and prosocial behaviors in children: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-29712-006http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2015.05.010&amp;issn=0190-7409&amp;isbn=&amp;volume=55&amp;issue=&amp;spage=37&amp;pages=37-47&amp;date=2015&amp;title=Children+and+Youth+Services+Review&amp;atitle=The+effectiveness+of+creative+bibliotherapy+for+internalizing%2C+externalizing%2C+and+prosocial+behaviors+in+children%3A+A+systematic+review.&amp;aulast=Montgomery&amp;pid=%3Cauthor%3EMontgomery%2C+Paul%3C%2Fauthor%3E%3CAN%3E2015-29712-006%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0190740915001590/1-s2.0-S0190740915001590-main.pdf?_tid=03ba5a00-04cd-11e7-8efe-00000aab0f27&amp;acdnat=1489066603_ff3fe9a463518bb9ca976899f2a5e127
VL  - 55
ER  -
TY  - JOUR
AB  - In developing countries, deficiencies of micronutrients are thought to have a major impact on child development; however, a consensus on the specific relationship between dietary zinc intake and cognitive function remains elusive. 

The aim of this systematic review was to examine the relationship between zinc intake, status and indices of cognitive function in children and adults. A systematic literature search was conducted using EMBASE, MEDLINE and Cochrane Library databases from inception to March 2014. Included studies were those that supplied zinc as supplements or measured dietary zinc intake. 

A meta-analysis of the extracted data was performed where sufficient data were available. Of all of the potentially relevant papers, 18 studies met the inclusion criteria, 12 of which were randomised controlled trials (RCTs; 11 in children and 1 in adults) and 6 were observational studies (2 in children and 4 in adults). Nine of the 18 studies reported a positive association between zinc intake or status with one or more measure of cognitive function. Meta-analysis of data from the adult&#039;s studies was not possible because of limited number of studies. 

A meta-analysis of data from the six RCTs conducted in children revealed that there was no significant overall effect of zinc intake on any indices of cognitive function: intelligence, standard mean difference of &lt;0.001 (95% confidence interval (CI) -0.12, 0.13) P=0.95; executive function, standard mean difference of 0.08 (95% CI, -0.06, 022) P=0.26; and motor skills standard mean difference of 0.11 (95% CI -0.17, 0.39) P=0.43. 

Heterogeneity in the study designs was a major limitation, hence only a small number (n=6) of studies could be included in the meta-analyses. Meta-analysis failed to show a significant effect of zinc supplementation on cognitive functioning in children though, taken as a whole, there were some small indicators of improvement on aspects of executive function and motor development following supplementation but high-quality RCTs are necessary to investigate this further.
AD  - Warthon-Medina, M. International Institute of Nutritional Sciences and Applied Food Safety Studies, University of Central Lancashire, Preston, UK. Moran, V H. Maternal and Infant Nutrition and Nurture Unit MAINN, University of Central Lancashire, Preston, UK. Stammers, A-L. International Institute of Nutritional Sciences and Applied Food Safety Studies, University of Central Lancashire, Preston, UK. Dillon, S. International Institute of Nutritional Sciences and Applied Food Safety Studies, University of Central Lancashire, Preston, UK. Qualter, P. School of Psychology, University of Central Lancashire, Preston, UK. Nissensohn, M. 1] Nutrition Research Group, Research Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain [2] Ciber Obn Physiopathology of Obesity and Nutrition, Institute of Health &quot;Carlos III&quot;, Madrid, Spain. Serra-Majem, L. 1] Nutrition Research Group, Research Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain [2] Ciber Obn Physiopathology of Obesity and Nutrition, Institute of Health &quot;Carlos III&quot;, Madrid, Spain. Lowe, N M. International Institute of Nutritional Sciences and Applied Food Safety Studies, University of Central Lancashire, Preston, UK.
AN  - 25920424
AU  - Warthon-Medina,
AU  - M.
AU  - Moran,
AU  - V.
AU  - H.
AU  - Stammers,
AU  - A.
AU  - L.
AU  - Dillon,
AU  - S.
AU  - Qualter,
AU  - P.
AU  - Nissensohn,
AU  - M.
AU  - Serra-Majem,
AU  - L.
AU  - Lowe,
AU  - N.
AU  - M.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1038/ejcn.2015.60
DP  - Ovid Technologies
J2  - Eur J Clin Nutr
KW  - Aged, 80 and over
KW  - Aging
KW  - Child Development
KW  - Child Nutritional Physiological Phenomena
KW  - Child, Preschool
KW  - *Cognition
KW  - Cognition Disorders/et [Etiology]
KW  - Cognition Disorders/pc [Prevention &amp; Control]
KW  - Cognitive Dysfunction/dh [Diet Therapy]
KW  - Cognitive Dysfunction/pc [Prevention &amp; Control]
KW  - Deficiency Diseases/dh [Diet Therapy]
KW  - Deficiency Diseases/pc [Prevention &amp; Control]
KW  - Diet/ae [Adverse Effects]
KW  - *Diet
KW  - *Dietary Supplements
KW  - Elder Nutritional Physiological Phenomena
KW  - *Evidence-Based Medicine
KW  - Executive Function
KW  - Humans
KW  - Motor Skills
KW  - *Neurogenesis
KW  - *Nutritional Status
KW  - *Zinc/ad [Administration &amp; Dosage]
KW  - Zinc/df [Deficiency]
KW  - Zinc/tu [Therapeutic Use]
KW  - J41CSQ7QDS (Zinc)
L1  - internal-pdf://1326835485/Warthon-2015-Zinc intake, status and indices o.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Warthon-Medina, M Moran, V H Stammers, A-L Dillon, S Qualter, P Nissensohn, M Serra-Majem, L Lowe, N M ejcn201560
PY  - 2015
SP  - 649-61
T2  - European Journal of Clinical Nutrition
TI  - Zinc intake, status and indices of cognitive function in adults and children: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25920424http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25920424&amp;id=doi:10.1038%2Fejcn.2015.60&amp;issn=0954-3007&amp;isbn=&amp;volume=69&amp;issue=6&amp;spage=649&amp;pages=649-61&amp;date=2015&amp;title=European+Journal+of+Clinical+Nutrition&amp;atitle=Zinc+intake%2C+status+and+indices+of+cognitive+function+in+adults+and+children%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Warthon-Medina&amp;pid=%3Cauthor%3EWarthon-Medina+M%3C%2Fauthor%3E%3CAN%3E25920424%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://www.nature.com/ejcn/journal/v69/n6/pdf/ejcn201560a.pdf
VL  - 69
ER  -
TY  - JOUR
AB  - **Objective: **
Suicidal behavior and self-harm are common in adolescents and are associated with elevated psychopathology, risk of suicide, and demand for clinical services. Despite recent advances in the understanding and treatment of self-harm and links between self-harm and suicide and risk of suicide attempt, progress in reducing suicide death rates has been elusive, with no substantive reduction in suicide death rates over the past 60 years. Extending prior reviews of the literature on treatments for suicidal behavior and repetitive self-harm in youth, this article provides a meta-analysis of randomized controlled trials (RCTs) reporting efficacy of specific pharmacological, social, or psychological therapeutic interventions (TIs) in reducing both suicidal and nonsuicidal self-harm adolescents. 

**Method:**
Data sources were identified by searching the Cochrane, Medline, PsychINFO, EMBASE, and PubMed databases as of May 2014. RCTs comparing specific therapeutic interventions versus treatment as usual (TAU) or placebo in adolescents (through age 18 years) with self-harm were included. 

**Results: **
Nineteen RCTs including 2,176 youth were analyzed. us included psychological and social interventions and no pharmacological interventions. The proportion of the adolescents who self-harmed over the follow-up period was lower in the intervention groups (28%) than in controls (33%) (test for overall effect z = 2.31; p = .02). TIs with the largest effect sizes were dialectical behavior therapy (DBT), cognitive-behavioral therapy (CBT), and mentalization-based therapy (MBT). There were no independent replications of efficacy of any TI. The pooled risk difference between TIs and TAU for suicide attempts and nonsuicidal self-harm considered separately was not statistically significant. 

**Conclusion: **
TIs to prevent self-harm appear to be effective. Independent replication of the results achieved by DBT, MBT, and CBT is a research priority.
AD  - [Ougrin, Dennis] Kings Coll London, Inst Psychiat, London SE5 8AF, England. [Ougrin, Dennis] South London &amp; Maudsley Natl Hlth Serv NHS Fdn T, London, England. [Tranah, Troy] South London &amp; Maudsley NHS Fdn Trust, London, England. [Stahl, Daniel; Moran, Paul] Kings Coll London, London WC2R 2LS, England. [Asarnow, Joan Rosebaum] Univ Calif Los Angeles, Los Angeles, CA USA. Ougrin, D (reprint author), Kings Coll London, Inst Psychiat, PO85,De Crespigny Pk, London SE5 8AF, England. dennis.ougrin@kcl.ac.uk
AN  - WOS:000348635300004
AU  - Ougrin,
AU  - D.
AU  - Tranah,
AU  - T.
AU  - Stahl,
AU  - D.
AU  - Moran,
AU  - P.
AU  - Asarnow,
AU  - J.
AU  - R.
DA  - Feb
DB  - Rekoding IN SUM_lme.enl
DO  - https://dx.doi.org/10.1016/j.jaac.2014.10.009
J2  - J. Am. Acad. Child Adolesc. Psychiatr.
KW  - self-harm randomized controlled trials meta-analysis RANDOMIZED CONTROLLED-TRIAL NOMINATED SUPPORT TEAM FOLLOW-UP EMERGENCY-DEPARTMENT FAMILY INTERVENTION EMPIRICAL-EVIDENCE CLINICAL-TRIALS YOUNG-PEOPLE BEHAVIOR INJURY Psychology, Developmental Pediatri
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CA0WX Times Cited: 0 Cited Reference Count: 65 Ougrin, Dennis Tranah, Troy Stahl, Daniel Moran, Paul Asarnow, Joan Rosebaum Moran, Paul/B-1740-2010 King&#039;s College London; South London and Maudsley NHS Foundation Trust; University of California, Los Angeles; National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at South London; Maudsley NHS Foundation Trust The authors&#039; time was paid for by the following institutions: King&#039;s College London (D.O., D.S., P.M.), South London and Maudsley NHS Foundation Trust (T.T.), and University of California, Los Angeles (J.R.A.). Drs. Stahl and Moran were also supported in part by the National Institute for Health Research (NIHR) Biomedical Research Centre for Mental Health at South London and Maudsley NHS Foundation Trust and King&#039;s College London. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, or the Department of Health. ELSEVIER SCIENCE BV AMSTERDAM J AM ACAD CHILD PSY
PY  - 2015
SP  - 97-107
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Therapeutic Interventions for Suicide Attempts and Self-Harm in Adolescents: Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000348635300004http://ac.els-cdn.com/S089085671400731X/1-s2.0-S089085671400731X-main.pdf?_tid=43b5d466-1674-11e5-bbda-00000aacb35e&amp;acdnat=1434712611_df00904cc2ddab40697d53563f062d2b
VL  - 54
ER  -
TY  - JOUR
AB  - **AIM: **
To conduct a systematic review and meta-analysis of the literature to assess efficacy of internet-delivered cognitive behavioural therapy (CBT) for child anxiety disorder. 

**METHOD: **
A systematic search of 7 electronic databases was conducted to assess CBT intervention for children with anxiety problems with remote delivery either entirely or partly via technology. Six articles reporting 7 studies were included. 

**RESULTS: **
The findings together suggested that CBT programmes involving computerised elements were well received by children and their families, and its efficacy was almost as favourable as clinic-based CBT. The mixture of children and adolescents included the studies, diverse range of programmes, and lack of consistency between study designs made it difficult to identify key elements of these programmes or draw conclusions on the treatment efficacy. 

**CONCLUSIONS: **
Analysis supports online delivery for wider access of this evidence-based therapy. Areas in need of improvement for this new method are indicated.

Copyright &copy; 2014. Published by Elsevier Ltd.
AD  - Rooksby,Maki. Dental Health Services and Research Unit, University of Dundee, Dundee, UK. Electronic address: maki.rooksby@googlemail.com. Elouafkaoui,Paula. Dundee Dental Education Centre, University of Dundee, UK. Humphris,Gerry. Bute Medical School, University of St. Andrews, St. Andrews, UK. Clarkson,Jan. Dental Health Services and Research Unit, University of Dundee, Dundee, UK; Dundee Dental Education Centre, University of Dundee, UK. Freeman,Ruth. Dental Health Services and Research Unit, University of Dundee, Dundee, UK.
AN  - 25527900
AU  - Rooksby,
AU  - M.
AU  - Elouafkaoui,
AU  - P.
AU  - Humphris,
AU  - G.
AU  - Clarkson,
AU  - J.
AU  - Freeman,
AU  - R.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.janxdis.2014.11.006
DP  - Ovid Technologies
J2  - J Anxiety Disord
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Rooksby, Maki Elouafkaoui, Paula Humphris, Gerry Clarkson, Jan Freeman, Ruth S0887-6185(14)00172-8 (United Kingdom Chief Scientist Office)
PY  - 2015
SP  - 83-92
T2  - Journal of Anxiety Disorders
TI  - Internet-assisted delivery of cognitive behavioural therapy (CBT) for childhood anxiety: systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25527900
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25527900&amp;id=doi:10.1016%2Fj.janxdis.2014.11.006&amp;issn=0887-6185&amp;isbn=&amp;volume=29&amp;issue=&amp;spage=83&amp;pages=83-92&amp;date=2015&amp;title=Journal+of+Anxiety+Disorders&amp;atitle=Internet-assisted+delivery+of+cognitive+behavioural+therapy+%28CBT%29+for+childhood+anxiety%3A+systematic+review+and+meta-analysis.&amp;aulast=Rooksby&amp;pid=%3Cauthor%3ERooksby+M%3C%2Fauthor%3E%3CAN%3E25527900%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0887618514001728/1-s2.0-S0887618514001728-main.pdf?_tid=bc5cc65a-165a-11e5-8cd0-00000aacb360&amp;acdnat=1434701646_c2f139fc55ba24d65df8f0ba12f6e8f3
VL  - 29
ER  -
TY  - JOUR
AB  - Successful treatment of parental depression may have a positive effect on the functioning and psychopathology of their children. 

We conducted a meta-analysis to examine the effects of psychotherapy for depressed mothers on their children and parental functioning. We used a database of randomized controlled trials examining the effects of psychotherapy for adult depression and selected trials comparing psychotherapy and control conditions in depressed mothers and reporting outcomes in their children and parental functioning. 

Nine studies were included. The quality of these studies was not optimal and the outcome instruments differed considerably from each other. 

The therapies resulted in significantly decreased levels of depression (g = 0.66) in the mothers. In the seven studies that reported outcomes on the mental health of children, a significant effect size was also found (g = 0.40). The eight studies examining mother-child interactions resulted in a significant effect size of g = 0.35, and the five studies examining parenting/marital distress had a pooled effect size of g = 0.67. 

We found that psychotherapy leads to decreased levels of depression in depressed mothers and also found indications that psychotherapy may have a positive effect on the mental health of their children and parenting/marital distress. However, more high-quality research is needed before a definite answer can be given.
AD  - Cuijpers,Pim. Department of Clinical Psychology, VU University Amsterdam, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands, p.cuijpers@psy.vu.nl.
AN  - 25522839
AU  - Cuijpers,
AU  - P.
AU  - Weitz,
AU  - E.
AU  - Karyotaki,
AU  - E.
AU  - Garber,
AU  - J.
AU  - Andersson,
AU  - G.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-014-0660-6
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
LA  - English
N1  - Cuijpers, Pim Weitz, Erica Karyotaki, Eirini Garber, Judy Andersson, Gerhard
PY  - 2015
SP  - 237-45
T2  - European Child &amp; Adolescent Psychiatry
TI  - The effects of psychological treatment of maternal depression on children and parental functioning: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25522839 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25522839&amp;id=doi:10.1007%2Fs00787-014-0660-6&amp;issn=1018-8827&amp;isbn=&amp;volume=24&amp;issue=2&amp;spage=237&amp;pages=237-45&amp;date=2015&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=The+effects+of+psychological+treatment+of+maternal+depression+on+children+and+parental+functioning%3A+a+meta-analysis.&amp;aulast=Cuijpers&amp;pid=%3Cauthor%3ECuijpers+P%3C%2Fauthor%3E%3CAN%3E25522839%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://download.springer.com/static/pdf/809/art%253A10.1007%252Fs00787-014-0660-6.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-014-0660-6&amp;token2=exp=1434977880~acl=%2Fstatic%2Fpdf%2F809%2Fart%25253A10.1007%25252Fs00787-014-0660-6.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-014-0660-6*~hmac=a0da49771b1dc38e09c21db7ba4c0e243626fc5862506a8e95c8463c81cdddfd
VL  - 24
ER  -
TY  - JOUR
AB  - **STUDY QUESTION: **
Is methylphenidate beneficial or harmful for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents? 

**METHODS: **
Electronic databases were searched up to February 2015 for parallel and crossover randomised clinical trials comparing methylphenidate with placebo or no intervention in children and adolescents with ADHD. Meta-analyses and trial sequential analyses (TSA) were conducted. Quality was assessed using GRADE. Teachers, parents, and observers rated ADHD symptoms and general behaviour. 

**STUDY ANSWER AND LIMITATIONS:** 
The analyses included 38 parallel group trials (n=5111, median treatment duration 49 days) and 147 crossover trials (n=7134, 14 days). The average age across all studies was 9.7 years. The analysis suggested a beneficial effect of methylphenidate on teacher rated symptoms in 19 parallel group trials (standardised mean difference (SMD) -0.77, n=1698), corresponding to a mean difference of -9.6 points on the ADHD rating scale. There was no evidence that methylphenidate was associated with an increase in serious adverse events (risk ratio 0.98, nine trials, n=1532; TSA adjusted intervention effect RR 0.91). Methylphenidate was associated with an increased risk of non-serious adverse events (1.29, 21 trials, n=3132; TSA adjusted RR 1.29). Teacher rated general behaviour seemed to improve with methylphenidate (SMD -0.87, five trials, n=668) A change of 7 points on the child health questionnaire (CHQ) has been deemed a minimal clinically relevant difference. The change reported in a meta-analysis of three trials corresponds to a mean difference of 8.0 points on the CHQ (range 0-100 points), which suggests that methylphenidate may improve parent reported quality of life (SMD 0.61, three trials, n=514). 96.8% of trials were considered high risk of bias trials according to the Cochrane guidelines. All outcomes were assessed very low quality according to GRADE. 

**WHAT THIS STUDY ADDS: **
The results suggest that among children and adolescents with a diagnosis of ADHD, methylphenidate may improve teacher reported symptoms of ADHD and general behaviour and parent reported quality of life. However, given the risk of bias in the included studies, and the very low quality of outcomes, the magnitude of the effects is uncertain. Methylphenidate is associated with an increased risk of non-serious but not serious adverse events. 

**FUNDING, COMPETING INTERESTS, DATA SHARING:**
Region Zealand Research Foundation and Copenhagen Trial Unit. Competing interests are given in the full paper on bmj.com. Full data are available in the version of this review published in The Cochrane Library.
AN  - 26608309
AU  - Storebo,
AU  - O.
AU  - J.
AU  - Krogh,
AU  - H.
AU  - B.
AU  - Ramstad,
AU  - E.
AU  - Moreira-Maia,
AU  - C.
AU  - R.
AU  - Holmskov,
AU  - M.
AU  - Skoog,
AU  - M.
AU  - Nilausen,
AU  - T.
AU  - D.
AU  - Magnusson,
AU  - F.
AU  - L.
AU  - Zwi,
AU  - M.
AU  - Gillies,
AU  - D.
AU  - Rosendal,
AU  - S.
AU  - Groth,
AU  - C.
AU  - Rasmussen,
AU  - K.
AU  - B.
AU  - Gauci,
AU  - D.
AU  - Kirubakaran,
AU  - R.
AU  - Forsbol,
AU  - B.
AU  - Simonsen,
AU  - E.
AU  - Gluud,
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1136/bmj.h5203
L1  - internal-pdf://1532698927/Storebo-2015-Methylphenidate for attention-def.pdf
PY  - 2015
SP  - h5203
T2  - BMJ
TI  - Methylphenidate for attention-deficit/hyperactivity disorder in children and adolescents: Cochrane systematic review with meta-analyses and trial sequential analyses of randomised clinical trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=26608309
UR  - https://www.bmj.com/content/bmj/351/bmj.h5203.full.pdf
VL  - 351
ER  -
TY  - JOUR
AB  - **Background: **
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by age-inappropriate levels of inattention, impulsivity and hyperactivity. School can be particularly challenging for children with ADHD. Few reviews have considered non-pharmacological interventions in school settings. 

**Objectives: **
To assess the effectiveness of non-pharmacological interventions delivered in school settings for pupils with, or at risk of, ADHD and to explore the factors that may enhance, or limit, their delivery. 

**Data sources: **
Twenty electronic databases (including PsycINFO, MEDLINE, EMBASE, Education Resources Information Centre, The Cochrane Library and Education Research Complete) were searched from 1980 to February-August 2013. Three separate searches were conducted for four systematic reviews; they were supplemented with forward and backwards citation chasing, website searching, author recommendations and hand-searches of key journals. 

**Review methods: **
The systematic reviews focused on (1) the effectiveness of school-based interventions for children with or at risk of ADHD; (2) quantitative research that explores attitudes towards school-based non-pharmacological interventions for pupils with ADHD; (3) qualitative research investigating the attitudes and experiences of children, teachers, parents and others using ADHD interventions in school settings; and (4) qualitative research exploring the experience of ADHD in school among pupils, their parents and teachers more generally. Methods of synthesis included a random-effects meta-analysis, meta-regression and narrative synthesis for review 1, narrative synthesis for review 2 and meta-ethnography and thematic analysis for reviews 3 and 4. 

**Results: **
For review 1, 54 controlled trials met the inclusion criteria. For the 36 meta-analysed randomised controlled trials, beneficial effects (p &lt; 0.05) were observed for several symptom and scholastic outcomes. Mean weighted effect sizes ranged from very small (d(+) &lt; 0.20) to large (d(+) &gt;= 0.80), but substantial heterogeneity in effect size estimates across studies was reported. Moderator analyses were not able to clarify which intervention features were linked with effectiveness. For review 2, 28 included studies revealed that educators&#039; attitudes towards interventions ranged in positivity. Most interventions were rated positively or neutrally across different studies. The only intervention that consistently recorded positive attitudes from educators was daily report cards. For review 3, 33 studies met the inclusion criteria. Key findings included tensions regarding the preferred format of interventions, particularly how structured interventions were and the extent to which they are tailored to the child with ADHD. There were mixed views about the impact of interventions, although it was clear that interventions both influence and are influenced by the relationships held by children with ADHD and participants&#039; attitudes towards school and ADHD. For review 4, 34 studies met the inclusion criteria. Key findings included the importance of causal attributions that teachers, parents and pupils made about ADHD symptoms, the decisions teachers made about treatment, the self-perceptions pupils developed about themselves, the role of the classroom environment and stigma in aggravating ADHD symptoms, and the significant barrier to treatment posed by the common presence of conflict in relationships between pupils-teachers, parents-teachers and pupils-peers in relation to ADHD. An overarching synthesis of the four reviews highlighted the importance of the context affecting interventions. It suggested that ADHD psychoeducation and relationship-building skills are potential implications for interventions. 

**Limitations: **
The breadth of both interventions and outcomes in the reviewed studies presented a challenge for categorisation, analysis and interpretation in reviews 1-3. Across reviews, relatively few studies were conducted in the UK, limiting the applicability of findings to UK education. In reviews 1 and 2, th poor methodological quality of some included studies was identified as a barrier to establishing effectiveness or comparing attitudes. In review 3 the descriptive analysis used by the majority of studies constrained theorising during synthesis. Studies in review 4 lacked detail regarding important issues like gender, pupil maturity and school level. 

**Conclusion: **
Findings suggest some beneficial effects of non-pharmacological interventions for ADHD used in school settings, but substantial heterogeneity in effect sizes was seen across studies. The qualitative reviews demonstrate the importance of the context in which interventions are used. Future work should consider more rigorous evaluation of interventions, as well as focus on what works, for whom and in which contexts. Gaps in current research present opportunities for the development and testing of standardised tools to describe interventions, agreement on gold-standard outcome measures assessing ADHD behaviour and testing a range of potential moderators alongside intervention trials.
AN  - WOS:000357161000001
AU  - Richardson,
AU  - M.
AU  - Moore,
AU  - D.
AU  - A.
AU  - Gwernan-Jones,
AU  - R.
AU  - Thompson-Coon,
AU  - J.
AU  - Ukoumunne,
AU  - O.
AU  - Rogers,
AU  - M.
AU  - Whear,
AU  - R.
AU  - Newlove-Delgado,
AU  - T.
AU  - V.
AU  - Logan,
AU  - S.
AU  - Morris,
AU  - C.
AU  - Taylor,
AU  - E.
AU  - Cooper,
AU  - P.
AU  - Stein,
AU  - K.
AU  - Garside,
AU  - R.
AU  - Ford,
AU  - T.
AU  - J.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3310/hta19450
J2  - Health Technol. Assess.
KW  - deficit hyperactivity disorder
KW  - disruptive behavior disorders
KW  - teacher
KW  - rating-scale
KW  - psychostimulant medication
KW  - treatment acceptability
KW  - mental-health
KW  - academic-performance
KW  - middle school
KW  - us children
KW  - service
KW  - use
KW  - Health Care Sciences &amp; Services
L1  - internal-pdf://2362996654/3002731.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: CL7OG Times Cited: 0 Cited Reference Count: 429 [Anonymous] Ford, Tamsin/0000-0001-5295-4904; Garside, Ruth/0000-0003-1649-4773 National Institute for Health Research Health Technology Assessment programme The National Institute for Health Research Health Technology Assessment programme. 0 7 34 Nihr journals library Southampton 2046-4924
PY  - 2015
SP  - 1-+
T2  - Health Technology Assessment
TI  - Non-pharmacological interventions for attention-deficit/hyperactivity disorder (ADHD) delivered in school settings: systematic reviews of quantitative and qualitative research
UR  - &lt;Go to ISI&gt;://WOS:000357161000001
VL  - 19
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Music interventions are widely used, but have not yet gained a place in guidelines for pediatric surgery or pediatric anesthesia. In this systematic review and meta-analysis we examined the effects of music interventions on pain, anxiety and distress in children undergoing invasive surgery. 

**DATA SOURCES: **
We searched 25 electronic databases from their first available date until October 2014. 

**STUDY SELECTION: **
Included were all randomized controlled trials with a parallel group, crossover or cluster design that included pediatric patients from 1 month to 18 years old undergoing minimally invasive or invasive surgical procedures, and receiving either live music therapy or recorded music. 

**DATA EXTRACTION AND SYNTHESIS: **
4846 records were retrieved from the searches, 26 full text reports were evaluated and data was extracted by two independent investigators. 

**MAIN OUTCOME MEASURES: **
Pain was measured with the Visual Analogue Scale, the Coloured Analogue Scale and the Facial Pain Scale. Anxiety and distress were measured with an emotional index scale (not validated), the Spielberger short State Trait Anxiety Inventory and a Facial Affective Scale. 

**RESULTS:**
Three RCTs were eligible for inclusion encompassing 196 orthopedic, cardiac and day surgery patients (age of 1 day to 18 years) receiving either live music therapy or recorded music. Overall a statistically significant positive effect was demonstrated on postoperative pain (SMD -1.07; 95%CI-2.08; -0.07) and on anxiety and distress (SMD -0.34 95% CI -0.66; -0.01 and SMD -0.50; 95% CI -0.84; - 0.16. 

**CONCLUSIONS AND RELEVANCE: **
This systematic review and meta-analysis indicates that music interventions may have a statistically significant effect in reducing post-operative pain, anxiety and distress in children undergoing a surgical procedure. Evidence from this review and other reviews suggests music therapy may be considered for clinical use.
AD  - van der Heijden, Marianne J E. Department of Pediatrics, Erasmus MC, Rotterdam, the Netherlands. Oliai Araghi, Sadaf. Department of Neuroscience, Erasmus MC, Rotterdam, the Netherlands. van Dijk, Monique. Department of Pediatrics, division of Neonatology and Department of Pediatric Surgery, Intensive care Erasmus MC, Rotterdam, the Netherlands. Jeekel, Johannes. Department of Neuroscience, Erasmus MC, Rotterdam, the Netherlands. Hunink, M G Myriam. Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands; Department of Radiology, Erasmus MC, Rotterdam, the Netherlands; Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
AN  - 26247769
AU  - van
AU  - der
AU  - Heijden,
AU  - M.
AU  - J.
AU  - Oliai
AU  - Araghi,
AU  - S.
AU  - van
AU  - Dijk,
AU  - M.
AU  - Jeekel,
AU  - J.
AU  - Hunink,
AU  - M.
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1371/journal.pone.0133608
DP  - Ovid Technologies
J2  - PLoS ONE
KW  - Anxiety
KW  - Databases, Factual
KW  - Humans
KW  - *Music Therapy
KW  - Pain/pa [Pathology]
KW  - *Pain Measurement
KW  - Randomized Controlled Trials as Topic
KW  - Stress, Psychological
L1  - internal-pdf://1203166131/van der-2015-The Effects of Perioperative Musi.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - van der Heijden, Marianne J E Oliai Araghi, Sadaf van Dijk, Monique Jeekel, Johannes Hunink, M G Myriam PONE-D-14-52232
PY  - 2015
SP  - e0133608
T2  - PLoS ONE [Electronic Resource]
TI  - The Effects of Perioperative Music Interventions in Pediatric Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26247769http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26247769&amp;id=doi:10.1371%2Fjournal.pone.0133608&amp;issn=1932-6203&amp;isbn=&amp;volume=10&amp;issue=8&amp;spage=e0133608&amp;pages=e0133608&amp;date=2015&amp;title=PLoS+ONE+%5BElectronic+Resource%5D&amp;atitle=The+Effects+of+Perioperative+Music+Interventions+in+Pediatric+Surgery%3A+A+Systematic+Review+and+Meta-Analysis+of+Randomized+Controlled+Trials.&amp;aulast=van+der+Heijden&amp;pid=%3Cauthor%3Evan+der+Heijden+MJ%3C%2Fauthor%3E%3CAN%3E26247769%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0133608&amp;type=printable
VL  - 10
ER  -
TY  - JOUR
AB  - **AIM **
To review and meta-analyse Mellow Parenting interventions for parent-child dyads at high risk of adverse developmental outcomes. 

**METHOD **
Using Preferred Reporting Items of Systematic reviews and Meta-Analyses (PRISMA) guidelines, we extracted all published evaluations of Mellow Parenting and Mellow Babies programmes. We identified published studies with randomized controlled trials, quasi-experimental or within-subject pre-post designs. We incorporated &#039;grey literature&#039; for unpublished publicly available evaluations. Effect sizes were calculated for impact of Mellow Parenting on parental mental health and child behaviour. Data were extracted on demographics, age of participants, country, and potential sources of bias. 

**RESULTS **
We identified eight papers, representing nine data sets, from five of which we calculated effect sizes. There was evidence of a medium treatment effect of Mellow Parenting compared with comparison groups on maternal well-being and child problems. Drop-out from treatment was variable. However, data were heterogeneous and there was evidence of methodological bias. 

**INTERPRETATION **
Our data give some support to claims for effectiveness of Mellow Parenting as a group intervention for families with multiple indices of developmental adversity. Given the methodological weaknesses of literature in the area, novel approaches are needed in future trials of low-budget complex interventions in non-commercial settings.
AD  - [MacBeth, Angus] Univ Edinburgh, Sch Hlth Social Sci, Edinburgh EH8 9AG, Midlothian, Scotland. [Law, James] Newcastle Univ, Sch Educ Commun &amp; Language Sci, Newcastle, England. [McGowan, Iain] Univ Ulster, Sch Nursing, Coleraine BT52 1SA, Londonderry, North Ireland. [Norrie, John] Univ Aberdeen, Ctr Healthcare Randomised Trials CHaRT, Aberdeen, Scotland. [Thompson, Lucy; Wilson, Philip] Univ Aberdeen, Ctr Rural Hlth, Aberdeen, Scotland. MacBeth, A (reprint author), Univ Edinburgh, Clin Psychol, Sch Hlth Social Sci, Old Med Sch, Edinburgh EH8 9AG, Midlothian, Scotland. angus.macbeth@ed.ac.uk
AN  - WOS:000367684600011
AU  - MacBeth,
AU  - A.
AU  - Law,
AU  - J.
AU  - McGowan,
AU  - I.
AU  - Norrie,
AU  - J.
AU  - Thompson,
AU  - L.
AU  - Wilson,
AU  - P.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/dmcn.12864
J2  - Dev. Med. Child Neurol.
KW  - randomized controlled-trial
KW  - triple p
KW  - antisocial-behavior
KW  - maternal
KW  - depression
KW  - children
KW  - borderline
KW  - disorders
KW  - infant
KW  - health
KW  - care
KW  - Neurosciences &amp; Neurology
KW  - Pediatrics
L1  - internal-pdf://4109851245/MacBeth-2015-Mellow Parenting_ systematic revi.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: DA3GG Times Cited: 2 Cited Reference Count: 41 MacBeth, Angus Law, James McGowan, Iain Norrie, John Thompson, Lucy Wilson, Philip MacBeth, Angus/0000-0002-0618-044X NHS Research Scotland Career Research Fellowship For part of the preparation period for this article, AM was supported by an NHS Research Scotland Career Research Fellowship. AM, LT, and PW have been involved in previous research into Mellow Parenting as well as other parenting programmes and have collaborated with the Mellow Parenting charity. PW has had travel and subsistence expenses reimbursed for attendance at a Mellow Parenting conference; otherwise the authors have not received financial recompense for any of these activities. We thank the Mellow Parenting charity for their advice about conducting this review. 2 5 14 Wiley-blackwell Hoboken 1469-8749
PY  - 2015
SP  - 1119-1128
T2  - Developmental Medicine and Child Neurology
TI  - Mellow Parenting: systematic review and meta-analysis of an intervention to promote sensitive parenting
UR  - &lt;Go to ISI&gt;://WOS:000367684600011
UR  - http://onlinelibrary.wiley.com/store/10.1111/dmcn.12864/asset/dmcn12864.pdf?v=1&amp;t=j02fcjpu&amp;s=1b4b932931c6bfc585ef2a7d7a5d9eb1034bfdb3
VL  - 57
ER  -
TY  - JOUR
AB  - **BACKGROUND AND OBJECTIVES: **
Supplementation and screening for iron-deficiency anemia (IDA) in young children may improve growth and development outcomes. The goal of this study was to review the evidence regarding the benefits and harms of screening and routine supplementation for IDA for the US Preventive Services Task Force. 

**METHODS: **
We searched Medline and Cochrane databases (1996-August 2014), as well as reference lists of relevant systematic reviews. We included trials and controlled observational studies regarding the effectiveness and harms of routine iron supplementation and screening in children ages 6 to 24 months conducted in developed countries. One author extracted data, which were checked for accuracy by a second author. Dual quality assessment was performed. 

**RESULTS: **
No studies of iron supplementation in young children reported on the diagnosis of neurodevelopmental delay. Five of 6 trials sparsely reporting various growth outcomes found no clear benefit of supplementation. After 3 to 12 months, Bayley Scales of Infant Development scores were not significantly different in 2 trials. Ten trials assessing iron supplementation in children reported inconsistent findings for hematologic measures. Evidence regarding the harms of supplementation was limited but did not indicate significant differences. No studies assessed the benefits or harms of screening or the association between improvement in impaired iron status and clinical outcomes. Studies may have been underpowered, and control factors varied and could have confounded results. 

**CONCLUSIONS: **
Although some evidence on supplementation for IDA in young children indicates improvements in hematologic values, evidence on clinical outcomes is lacking. No randomized controlled screening studies are available. 

Copyright &copy; 2015 by the American Academy of Pediatrics.
AD  - McDonagh, Marian S. Department of Medical Informatics &amp; Clinical Epidemiology, Pacific Northwest Evidence-based Practice Center, Oregon Health &amp; Science University, Portland, Oregon mcdonagh@ohsu.edu. Blazina, Ian. Department of Medical Informatics &amp; Clinical Epidemiology, Pacific Northwest Evidence-based Practice Center, Oregon Health &amp; Science University, Portland, Oregon. Dana, Tracy. Department of Medical Informatics &amp; Clinical Epidemiology, Pacific Northwest Evidence-based Practice Center, Oregon Health &amp; Science University, Portland, Oregon. Cantor, Amy. Department of Medical Informatics &amp; Clinical Epidemiology, Pacific Northwest Evidence-based Practice Center, Oregon Health &amp; Science University, Portland, Oregon. Bougatsos, Christina. Department of Medical Informatics &amp; Clinical Epidemiology, Pacific Northwest Evidence-based Practice Center, Oregon Health &amp; Science University, Portland, Oregon.
AN  - 25825534
AU  - McDonagh,
AU  - M.
AU  - S.
AU  - Blazina,
AU  - I.
AU  - Dana,
AU  - T.
AU  - Cantor,
AU  - A.
AU  - Bougatsos,
AU  - C.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2014-3979
DP  - Ovid Technologies
J2  - Pediatrics
KW  - *Anemia, Iron-Deficiency/di [Diagnosis]
KW  - *Anemia, Iron-Deficiency/dt [Drug Therapy]
KW  - Anemia, Iron-Deficiency/ep [Epidemiology]
KW  - Anemia, Iron-Deficiency/pc [Prevention &amp; Control]
KW  - Child Development/de [Drug Effects]
KW  - Controlled Clinical Trials as Topic
KW  - Evidence-Based Medicine
KW  - Female
KW  - Follow-Up Studies
KW  - Humans
KW  - Infant
KW  - Iron Compounds
KW  - Male
KW  - *Mass Screening
KW  - Observational Studies as Topic
KW  - Treatment Outcome
KW  - 0 (Iron Compounds)
L1  - internal-pdf://3809178389/McDonagh-2015-Screening and routine supplement.pdf
LA  - English
M3  - Research Support, U.S. Gov&#039;t, P.H.S. Review
N1  - McDonagh, Marian S Blazina, Ian Dana, Tracy Cantor, Amy Bougatsos, Christina peds.2014-3979
PY  - 2015
SP  - 723-33
T2  - Pediatrics
TI  - Screening and routine supplementation for iron deficiency anemia: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25825534http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25825534&amp;id=doi:10.1542%2Fpeds.2014-3979&amp;issn=0031-4005&amp;isbn=&amp;volume=135&amp;issue=4&amp;spage=723&amp;pages=723-33&amp;date=2015&amp;title=Pediatrics&amp;atitle=Screening+and+routine+supplementation+for+iron+deficiency+anemia%3A+a+systematic+review.&amp;aulast=McDonagh&amp;pid=%3Cauthor%3EMcDonagh+MS%3C%2Fauthor%3E%3CAN%3E25825534%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://pediatrics.aappublications.org/content/pediatrics/135/4/723.full.pdf
VL  - 135
ER  -
TY  - JOUR
AB  - **CONTEXT: **
Mixed findings exist on whether stimulant medications alter youth sleep. 

**OBJECTIVE: **
To determine the effect of stimulant medications on sleep. 

**DATA STUDIES: **
Studies published through March 2015 were collected via CINAHL, PsycINFO, and PubMed. References of retrieved articles were reviewed. 

**STUDY SELECTION:** 
Eligibility criteria included studies with children/adolescents who had attention-deficit/hyperactivity disorder (ADHD), random assignment to stimulants, and objective sleep measurement. Studies that did not include information about key variables were excluded. 

**DATA EXTRACTION: **
Study-level, child-level, and sleep data were extracted by 2 independent coders. Effect sizes were calculated by using random effects models. Potential moderators were examined by using mixed effect models. 

**RESULTS: **
A total of 9 articles (N = 246) were included. For sleep latency, the adjusted effect size (0.54) was significant, indicating that stimulants produce longer sleep latencies. Frequency of dose per day was a significant moderator. For sleep efficiency, the adjusted effect size (-0.32) was significant. Significant moderators included length of time on medication, number of nights of sleep assessed, polysomnography/actigraphy, and gender. Specifically, the effect of medication was less evident when youth were taking medication longer. For total sleep time, the effect size (-0.59) was significant, such that stimulants led to shorter sleep duration.

**LIMITATIONS: **
Limitations include few studies, limited methodologic variability, and lack of unpublished studies. 

**CONCLUSIONS: **
Stimulant medication led to longer sleep latency, worse sleep efficiency, and shorter sleep duration. Overall, youth had worse sleep on stimulant medications. It is recommended that pediatricians carefully monitor sleep problems and adjust treatment to promote optimal sleep. 

Copyright &copy; 2015 by the American Academy of Pediatrics.
AD  - Kidwell, Katherine M. Department of Psychology, University of Nebraska-Lincoln, Lincoln, Nebraska kkidwell@huskers.unl.edu. Van Dyk, Tori R. Department of Psychology, University of Nebraska-Lincoln, Lincoln, Nebraska. Lundahl, Alyssa. Department of Psychology, University of Nebraska-Lincoln, Lincoln, Nebraska. Nelson, Timothy D. Department of Psychology, University of Nebraska-Lincoln, Lincoln, Nebraska.
AN  - 26598454
AU  - Kidwell,
AU  - K.
AU  - M.
AU  - Van
AU  - Dyk,
AU  - T.
AU  - R.
AU  - Lundahl,
AU  - A.
AU  - Nelson,
AU  - T.
AU  - D.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2015-1708
DP  - Ovid Technologies
J2  - Pediatrics
KW  - Adolescent
KW  - *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy]
KW  - Attention Deficit Disorder with Hyperactivity/pp [Physiopathology]
KW  - Central Nervous System Stimulants/ae [Adverse Effects]
KW  - *Central Nervous System Stimulants/tu [Therapeutic Use]
KW  - Child
KW  - Child, Preschool
KW  - Female
KW  - Humans
KW  - Male
KW  - Polysomnography
KW  - *Sleep/de [Drug Effects]
KW  - 0 (Central Nervous System Stimulants)
L1  - internal-pdf://1739006268/Kidwell-2015-Stimulant Medications and Sleep f.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Kidwell, Katherine M Van Dyk, Tori R Lundahl, Alyssa Nelson, Timothy D peds.2015-1708
PY  - 2015
SP  - 1144-53
T2  - Pediatrics
TI  - Stimulant Medications and Sleep for Youth With ADHD: A Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26598454http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26598454&amp;id=doi:10.1542%2Fpeds.2015-1708&amp;issn=0031-4005&amp;isbn=&amp;volume=136&amp;issue=6&amp;spage=1144&amp;pages=1144-53&amp;date=2015&amp;title=Pediatrics&amp;atitle=Stimulant+Medications+and+Sleep+for+Youth+With+ADHD%3A+A+Meta-analysis.&amp;aulast=Kidwell&amp;pid=%3Cauthor%3EKidwell+KM%3C%2Fauthor%3E%3CAN%3E26598454%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://pediatrics.aappublications.org/content/pediatrics/136/6/1144.full.pdf
VL  - 136
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
There is a lack of comparative effectiveness research among attention deficit hyperactivity disorder (ADHD) drugs in terms of efficacy and acceptability, where bupropion is compared with atomoxetine, lisdexamfetamine and methylphenidate. The main aim of this work was to compare the efficacy and acceptability of these drugs in children and adolescents using a metaanalysis. 

**METHODS: **
A literature search was conducted to identify double-blind, placebo-controlled, noncrossover studies of ADHD. PubMed/Medline and Clinicaltrials.gov were searched. Comparative drug efficacy to placebo was calculated based on the standardized mean difference (SMD), while the comparative drug acceptability (all cause discontinuation) to placebo was estimated on the odds ratio (OR). 

**RESULTS: **
In total 28 trials were included in the meta-analysis. Efficacy in reducing ADHD symptoms compared to placebo was small for bupropion (SMD=-0.32, 95% CI; -0.69, 0.05), while modest efficacy was shown for atomoxetine (SMD=-0.68, 95% CI; -0.76, -0.59) and methylphenidate (SMD=-0.75, 95% CI; -0.98, -0.52) and high efficacy was observed for lisdexamfetamine (SMD=-1.28, 95% CI; -1.84, -0.71). Compared to placebo treatment discontinuation was statistically significantly lower for methylphenidate (OR=0.35, 95% CI; 0.24, 0.52), while it was not significantly different for atomoxetine (OR=0.91, 95% CI; 0.66, 1.24), lisdexamfetamine (OR=0.60, 95% CI, 0.22, 1.65), and bupropion (OR=1.64, 95% CI; 0.5, 5.43). 

**LIMITATIONS: **
The heterogeneity was high, except in atomoxetine trials. The crossover studies were excluded. The effect sizes at specific time points were not computed. Studies with comorbid conditions, except those reporting on oppositional defiant disorder, were also excluded. All studies involving MPH were combined. 

**CONCLUSIONS: **
The results suggest that lisdexamfetamine has the best benefit risk balance and has promising potential for treating children and adolescents with ADHD. More research is needed for a better clinical evaluation of bupropion. 

Copyright &copy; 2015 Elsevier B.V. All rights reserved.
AD  - Stuhec, Matej. Clinical Pharmacy Department, Ormoz Psychiatric hospital, Ptujska Cesta 33, 2270 Ormoz, Slovenia, European Union. Electronic address: matejstuhec@gmail.com. Munda, Barbara. Chair of Social Pharmacy, Faculty of Pharmacy, University of Ljubljana, Askerceva cesta 7, 1000 Ljubljana, Slovenia, European Union. Svab, Vesna. Department of Psychiatry, Faculty of Medicine, University Ljubljana, Vrazov trg 2, 1104 Ljubljana, Slovenia, European Union. Locatelli, Igor. Chair of Social Pharmacy, Faculty of Pharmacy, University of Ljubljana, Askerceva cesta 7, 1000 Ljubljana, Slovenia, European Union.
AN  - 25813457
AU  - Stuhec,
AU  - M.
AU  - Munda,
AU  - B.
AU  - Svab,
AU  - V.
AU  - Locatelli,
AU  - I.
DA  - Jun 01
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jad.2015.03.006
DP  - Ovid Technologies
J2  - J Affect Disord
KW  - Adolescent
KW  - *Adrenergic Uptake Inhibitors/tu [Therapeutic Use]
KW  - Atomoxetine Hydrochloride
KW  - *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy]
KW  - *Bupropion/tu [Therapeutic Use]
KW  - Central Nervous System Stimulants/tu [Therapeutic Use]
KW  - Child
KW  - Comparative Effectiveness Research
KW  - *Dextroamphetamine/tu [Therapeutic Use]
KW  - Double-Blind Method
KW  - Female
KW  - Humans
KW  - Lisdexamfetamine Dimesylate
KW  - Male
KW  - *Methylphenidate/tu [Therapeutic Use]
KW  - *Patient Acceptance of Health Care/sn [Statistics &amp; Numerical Data]
KW  - *Propylamines/tu [Therapeutic Use]
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
KW  - 0 (Adrenergic Uptake Inhibitors)
KW  - 0 (Central Nervous System Stimulants)
KW  - 0 (Propylamines)
KW  - 01ZG3TPX31 (Bupropion)
KW  - 207ZZ9QZ49 (Methylphenidate)
KW  - 57WVB6I2W0 (Atomoxetine Hydrochloride)
KW  - SJT761GEGS (Lisdexamfetamine Dimesylate)
KW  - TZ47U051FI (Dextroamphetamine)
L1  - internal-pdf://3279146128/Stuhec-2015-Comparative efficacy and acceptabi.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Stuhec, Matej Munda, Barbara Svab, Vesna Locatelli, Igor S0165-0327(15)00133-0
PY  - 2015
SP  - 149-59
T2  - Journal of Affective Disorders
TI  - Comparative efficacy and acceptability of atomoxetine, lisdexamfetamine, bupropion and methylphenidate in treatment of attention deficit hyperactivity disorder in children and adolescents: a meta-analysis with focus on bupropion
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25813457http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25813457&amp;id=doi:10.1016%2Fj.jad.2015.03.006&amp;issn=0165-0327&amp;isbn=&amp;volume=178&amp;issue=&amp;spage=149&amp;pages=149-59&amp;date=2015&amp;title=Journal+of+Affective+Disorders&amp;atitle=Comparative+efficacy+and+acceptability+of+atomoxetine%2C+lisdexamfetamine%2C+bupropion+and+methylphenidate+in+treatment+of+attention+deficit+hyperactivity+disorder+in+children+and+adolescents%3A+a+meta-analysis+with+focus+on+bupropion.&amp;aulast=Stuhec&amp;pid=%3Cauthor%3EStuhec+M%3C%2Fauthor%3E%3CAN%3E25813457%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0165032715001330/1-s2.0-S0165032715001330-main.pdf?_tid=9206be40-04d0-11e7-90d2-00000aacb35f&amp;acdnat=1489068130_8887e288b8c691e97c05b98d11568ac5
VL  - 178
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Psychotropic medications are frequently used to treat challenging behaviour in children with intellectual disabilities, despite a lack of evidence for their efficacy. This systematic review and meta-analysis aimed to determine the safety and efficacy of pharmacological interventions for challenging behaviour among children with intellectual disabilities. 

**METHODS: **
Electronic databases were searched and supplemented with a hand search of reference lists and trial registries. Randomised controlled trials of pharmacological interventions for challenging behaviour among children with intellectual disabilities were included. Data were analysed using meta-analysis or described narratively if meta-analysis was not possible. For quality assessment, the Cochrane Risk of Bias tool and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach were used. 

**RESULTS: **
Fourteen studies including 912 participants met inclusion criteria. Antipsychotic medication reduced challenging behaviour among children with intellectual disabilities in the short-term (SMD=-1.09, p&lt;0.001 for risperidone; SMD=-0.64, p &lt;0.001 for aripiprazole). However, there were significant side-effects including elevated prolactin levels (SMD=3.22, p&lt;0.001) and weight gain (SMD=0.82, p&lt;0.001). Evidence was inconclusive regarding the effectiveness of anticonvulsants and antioxidants for reducing challenging behaviour. The quality of all evidence was low and there were no long term follow up studies. 

**CONCLUSIONS: **
Antipsychotic medications appear to be effective for reducing challenging behaviour in the short-term among children with intellectual disabilities, but they carry a risk of significant side effects. Findings from this review must be interpreted with caution as studies were typically of low quality and most outcomes were based on a small number of studies. Further long-term, high-quality research is needed to determine the effectiveness and safety of psychotropic medication for reducing challenging behaviour.
AD  - McQuire, Cheryl. National Collaborating Centre for Mental Health, Royal College of Psychiatrists, 21 Prescot Street, London, E1 8BB, UK. mcquirec1@cardiff.ac.uk. Hassiotis, Angela. Division of Psychiatry, University College London, Charles Bell House, 1st and 2nd Floor, 67-73 Riding House Street, London, W1W 7EJ, UK. a.hassiotis@ucl.ac.uk. Harrison, Bronwyn. National Collaborating Centre for Mental Health, Royal College of Psychiatrists, 21 Prescot Street, London, E1 8BB, UK. bharrison.rcpsych@live.co.uk. Pilling, Stephen. Centre for Outcomes Research and Effectiveness, University College London, 1-19 Torrington Place, London, WC1E 7HB, UK. spilling@ucl.ac.uk.
AN  - 26611280
AU  - McQuire,
AU  - C.
AU  - Hassiotis,
AU  - A.
AU  - Harrison,
AU  - B.
AU  - Pilling,
AU  - S.
DA  - Nov 26
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/s12888-015-0688-2
DP  - Ovid Technologies
J2  - BMC Psychiatry
KW  - Adaptation, Psychological
KW  - Adolescent
KW  - Anticonvulsants/tu [Therapeutic Use]
KW  - Antioxidants/tu [Therapeutic Use]
KW  - Antipsychotic Agents/tu [Therapeutic Use]
KW  - Child
KW  - *Child Behavior Disorders/dt [Drug Therapy]
KW  - Female
KW  - Humans
KW  - *Intellectual Disability/dt [Drug Therapy]
KW  - Male
KW  - Patient Safety
KW  - Patient Satisfaction
KW  - Prolactin/me [Metabolism]
KW  - Quality of Life
KW  - Randomized Controlled Trials as Topic
KW  - Weight Gain/de [Drug Effects]
KW  - gamma-Aminobutyric Acid/aa [Analogs &amp; Derivatives]
KW  - 0 (Anticonvulsants)
KW  - 0 (Antioxidants)
KW  - 0 (Antipsychotic Agents)
KW  - 56-12-2 (gamma-Aminobutyric Acid)
KW  - 9002-62-4 (Prolactin)
L1  - internal-pdf://0299333655/McQuire-2015-Pharmacological interventions for.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - McQuire, Cheryl Hassiotis, Angela Harrison, Bronwyn Pilling, Stephen 10.1186/s12888-015-0688-2
PY  - 2015
SP  - 303
T2  - BMC Psychiatry
TI  - Pharmacological interventions for challenging behaviour in children with intellectual disabilities: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26611280http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26611280&amp;id=doi:10.1186%2Fs12888-015-0688-2&amp;issn=1471-244X&amp;isbn=&amp;volume=15&amp;issue=1&amp;spage=303&amp;pages=303&amp;date=2015&amp;title=BMC+Psychiatry&amp;atitle=Pharmacological+interventions+for+challenging+behaviour+in+children+with+intellectual+disabilities%3A+a+systematic+review+and+meta-analysis.&amp;aulast=McQuire&amp;pid=%3Cauthor%3EMcQuire+C%3C%2Fauthor%3E%3CAN%3E26611280%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662033/pdf/12888_2015_Article_688.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Animal assisted intervention (AAI), which has been defined as the use of an animal to provide therapeutic benefit based on a positive relationship between the client and the animal, is a therapy option for children with autism spectrum disorder (ASD); therefore, it is beneficial to review studies that evaluated its effectiveness. 

A systematic search identified 20 studies that were assessed in terms of (a) participant characteristics, (b) independent variables, (c) dependent variables, (d) study outcomes, and (e) certainty of evidence. Although AAI studies reported either positive or mixed results, multiple methodological flaws were identified across the literature, which is cause for concern when determining intervention efficacy. 

Because of these contradictory findings and research design limitations, additional inquiry is needed. As such, caregivers and practitioners should exercise caution in selecting AAI as part of an intervention package for children with ASD.
AD  - [Davis, Tonya N.; Scalzo, Rachel; Butler, Erin; Stauffer, Megan; Farah, Yara N.; Perez, Scott; Mainor, Kristen; Clark, Cathryn; Miller, Stacy; Kobylecky, Alicia; Coviello, Laura] Baylor Univ, Waco, TX 76798 USA. Davis, TN (reprint author), Baylor Univ, One Bear Pl 97031, Waco, TX 76798 USA. Tonya_Davis@baylor.edu
AN  - WOS:000359962100006
AU  - Davis,
AU  - T.
AU  - N.
AU  - Scalzo,
AU  - R.
AU  - Butler,
AU  - E.
AU  - Stauffer,
AU  - M.
AU  - Farah,
AU  - Y.
AU  - N.
AU  - Perez,
AU  - S.
AU  - Mainor,
AU  - K.
AU  - Clark,
AU  - C.
AU  - Miller,
AU  - S.
AU  - Kobylecky,
AU  - A.
AU  - Coviello,
AU  - L.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10803-012-1707-5
J2  - Educ. Train. Autism Dev. Disabil.
KW  - rating-scale
KW  - guinea-pigs
KW  - therapy
KW  - behavior
KW  - dogs
KW  - communication
KW  - Education &amp; Educational Research
KW  - Rehabilitation
L1  - internal-pdf://2158804900/out(12).pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CP5YS Times Cited: 0 Cited Reference Count: 60 Davis, Tonya N. Scalzo, Rachel Butler, Erin Stauffer, Megan Farah, Yara N. Perez, Scott Mainor, Kristen Clark, Cathryn Miller, Stacy Kobylecky, Alicia Coviello, Laura 0 14 64 Council exceptional children Arlington
PY  - 2015
SP  - 316-329
T2  - Education and Training in Autism and Developmental Disabilities
TI  - Animal Assisted Interventions for Children with Autism Spectrum Disorder: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000359962100006
VL  - 50
ER  -
TY  - JOUR
AB  - **Background**
There is a lack of knowledge about specific effective ingredients of prevention programs for youth at risk for persistent delinquent behavior. The present study combines findings of previous studies by examining the effectiveness of programs in preventing persistent juvenile delinquency and by studying which particular program, sample, and study characteristics contribute to the effects. Information on effective ingredients offers specific indications of how programs may be improved in clinical practice. 

**Method**
A literature search in PsychINFO, ERIC, PubMed, Sociological Abstracts, Criminal Justice Abstracts, and Google Scholar was performed. Only (quasi)experimental studies and studies that focused on adolescents at risk for (persistent) delinquent behavior were included. Multilevel meta-analysis was conducted on 39 studies (N=9,084). Participants&#039; ages ranged from 6 to 20years (M=14years, SD=2.45). 

**Results**
The overall effect size was significant and small in magnitude (d=0.24, p&lt;.001). Behavioral-oriented programs, focusing on parenting skills training, behavioral modeling, or behavioral contracting yielded the largest effects. Multimodal programs and programs carried out in the family context proved to be more beneficial than individual and group-based programs. Less intensive programs yielded larger effects. 

**Conclusions**
Prevention programs have positive effects on preventing persistent juvenile delinquency. In order to improve program effectiveness, interventions should be behavioral-oriented, delivered in a family or multimodal format, and the intensity of the program should be matched to the level of risk of the juvenile.
AD  - [de Vries, Sanne L. A.; Hoeve, Machteld; Assink, Mark; Stams, Geert Jan J. M.; Asscher, Jessica J.] Univ Amsterdam, Res Inst Child Dev &amp; Educ, NL-1001 NG Amsterdam, Netherlands. de Vries, SLA (reprint author), Univ Amsterdam, Res Inst Child Dev &amp; Educ, POB 15780, NL-1001 NG Amsterdam, Netherlands. l.a.devries@uva.nl
AN  - WOS:000348863800002
AU  - de,
AU  - Vries,
AU  - S.
AU  - L.
AU  - A.
AU  - Hoeve,
AU  - M.
AU  - Assink,
AU  - M.
AU  - Stams,
AU  - G.
AU  - J.
AU  - J.
AU  - M.
AU  - Asscher,
AU  - J.
AU  - J.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jcpp.12320
J2  - J. Child Psychol. Psychiatry
KW  - Effectiveness
KW  - prevention
KW  - juvenile delinquency
KW  - meta-analysis
KW  - antisocial-behavior
KW  - diversion programs
KW  - conduct problems
KW  - follow-up
KW  - metaanalysis
KW  - offenders
KW  - intervention
KW  - recidivism
KW  - justice
KW  - outcomes
KW  - Psychology
KW  - Psychiatry
L1  - internal-pdf://0953532793/de-2015-Practitioner Review_ Effective ingredi.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CA4GX Times Cited: 4 Cited Reference Count: 109 de Vries, Sanne L. A. Hoeve, Machteld Assink, Mark Stams, Geert Jan J. M. Asscher, Jessica J. Figueroa Ossa, Ulda Omar/N-5821-2016 ZonMw, The Netherlands Organization for Health Research and Development [157000.4006] This work was supported by ZonMw, The Netherlands Organization for Health Research and Development (project 157000.4006). The authors have declared that they have no potential or competing conflicts of interest. 4 55 Wiley-blackwell Hoboken 1469-7610
PY  - 2015
SP  - 108-121
T2  - Journal of Child Psychology and Psychiatry
TI  - Practitioner Review: Effective ingredients of prevention programs for youth at risk of persistent juvenile delinquency - recommendations for clinical practice
UR  - &lt;Go to ISI&gt;://WOS:000348863800002
UR  - http://onlinelibrary.wiley.com/store/10.1111/jcpp.12320/asset/jcpp12320.pdf?v=1&amp;t=j02dqqpo&amp;s=0884895d979b013bec8407e4cf45e0c8aacc1134
VL  - 56
ER  -
TY  - JOUR
AB  - **AIMS:**
To examine the effects of physical activity and exercise interventions on body mass index, subsequent physical activity and psychological symptoms for overweight and obese adolescents (12-18 years).

**BACKGROUND: **
Overweight and obesity have increased among adolescents globally and physical activity has decreased. Healthcare systems face challenges promoting physical activity and in treating obesity. Promotion of physical activity must be effective and school nurses should be equipped with the information and resources required to implement counselling for overweight and obese adolescents. 

**DESIGN: **
A systematic review of randomized controlled trials was conducted according to procedures by the Centre for Reviews and Dissemination and the Joanna Briggs Institute. 

**DATA SOURCES: **
Research studies published between 1950-2013 were identified from the following databases. CINAHL, MEDLINE (Ovid) and PsycINFO. 

**REVIEW METHODS: **
Selected studies were reviewed for quality and a risk-of-bias assessment was conducted for the included studies. A narrative synthesis was used to report results, while a fixed-effect meta-analysis was used to analyse the interventions effects on physical activity and body mass index. 

**RESULTS: **
Fourteen published studies were included to this review. Supervised exercise interventions most affected adolescents&#039; body mass index. The interventions effect on adolescents&#039; physical activity was small and heterogeneous. Two interventions positively affected psychological symptoms. 

**CONCLUSION: **
Interventions were complex, with more than one component and the aspect that effectively promotes physical activity in obese adolescents was not clear. However, it seems that exercise interventions affect the body mass index of overweight or obese adolescents. Interventions that include a component for promoting physical activity with or without supervised exercise can affect subsequent physical activity and body mass index. 

Copyright &copy; 2015 John Wiley &amp; Sons Ltd.
AD  - Ruotsalainen, Heidi. Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Finland. Kyngas, Helvi. Institute of Health Sciences, University of Oulu, Finland. Kyngas, Helvi. Northern Ostrobothnia Hospital District, Oulu, Finland. Tammelin, Tuija. LIKES-Research Center for Sport and Health Sciences, Jyvaskyla, Finland. Kaariainen, Maria. Institute of Health Sciences, University of Oulu, Finland.
AN  - 26031309
AU  - Ruotsalainen,
AU  - H.
AU  - Kyngas,
AU  - H.
AU  - Tammelin.
AU  - T.
AU  - Kaariainen,
AU  - M.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jan.12696
DP  - Ovid Technologies
J2  - J Adv Nurs
KW  - Adolescent
KW  - Body Image
KW  - *Body Mass Index
KW  - Child
KW  - Exercise/px [Psychology]
KW  - *Exercise Therapy/mt [Methods]
KW  - Female
KW  - Humans
KW  - Male
KW  - *Mental Disorders/et [Etiology]
KW  - *Mental Disorders/px [Psychology]
KW  - Mental Disorders/th [Therapy]
KW  - Obesity/px [Psychology]
KW  - Obesity/th [Therapy]
KW  - Overweight/px [Psychology]
KW  - *Overweight/th [Therapy]
KW  - Patient Satisfaction
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
L1  - internal-pdf://3803165390/Ruotsalainen-2015-Systematic review of physica.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Ruotsalainen, Heidi Kyngas, Helvi Tammelin, Tuija Kaariainen, Maria
PY  - 2015
SP  - 2461-77
T2  - Journal of Advanced Nursing
TI  - Systematic review of physical activity and exercise interventions on body mass indices, subsequent physical activity and psychological symptoms in overweight and obese adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26031309http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26031309&amp;id=doi:10.1111%2Fjan.12696&amp;issn=0309-2402&amp;isbn=&amp;volume=71&amp;issue=11&amp;spage=2461&amp;pages=2461-77&amp;date=2015&amp;title=Journal+of+Advanced+Nursing&amp;atitle=Systematic+review+of+physical+activity+and+exercise+interventions+on+body+mass+indices%2C+subsequent+physical+activity+and+psychological+symptoms+in+overweight+and+obese+adolescents.&amp;aulast=Ruotsalainen&amp;pid=%3Cauthor%3ERuotsalainen+H%3C%2Fauthor%3E%3CAN%3E26031309%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1111/jan.12696/asset/jan12696.pdf?v=1&amp;t=j02g9887&amp;s=24ff18a6dedd0831f2589b43cd701a0d64848945
VL  - 71
ER  -
TY  - JOUR
AB  - The aims are to evaluate the efficacy and safety of sodium valproate for children with Tourette&#039;s syndrome (TS). We searched PubMed, EMBASE, the Cochrane library, Cochrane Central, CBM, CNKI, VIP, WANG FANG database and relevant reference lists. Five RCTs (N=247) and five case series (N=163) studies were included. 

Only one RCT (93 patients) evaluated total YGTSS scores and there was significant difference in the reduction of total YGTSS scores between sodium valproate and the control group (3.50+/-4.59 vs 7.86+/-7.03, P&lt;0.01). One RCT (30 patients) evaluated motor and vocal tics, and there was significant difference in the reduction of motor and vocal tics scores between sodium valproate and haloperidol (10.45+/-4.15 vs 14.92+/-3.01, P&lt;0.01). 

Meta-analysis of three RCTs (N=124) showed there was no significant difference in the reduction of the number of tics between sodium valproate and the positive control group [Relative Risk (RR)=1.09, 95%CI (0.92, 1.30), P=0.30]. The pooled proportion in five case series studies which used tics symptom improvement self-defined by authors was 80.7% (95% CI: 73.7-86.2, I(2)=0). No fatal side effects were reported. 

In conclusion, based on the limited evidence, the routine use of sodium valproate for treatment of TS in children is not recommended. Further well-conducted trials that examine long-term outcomes are required. 

Copyright &copy; 2015. Published by Elsevier Ireland Ltd.
AD  - Yang, Chun-Song. Department of Pharmacy, Evidence-based Pharmacy Center, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. Electronic address: yangchunsong_123@126.com. Zhang, Ling-Li. Department of Pharmacy, Evidence-based Pharmacy Center, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. Electronic address: zhlingli@sina.com. Lin, Yun-Zhu. Department of Pharmacy, Evidence-based Pharmacy Center, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. Electronic address: 36377156@qq.com. Guo, Qin. Department of Pediatrics, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. Electronic address: joy1122@163.com.
AN  - 25724485
AU  - Yang,
AU  - C.
AU  - S.
AU  - Zhang,
AU  - L.
AU  - L.
AU  - Lin,
AU  - Y.
AU  - Z.
AU  - Guo,
AU  - Q.
DA  - Apr 30
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.psychres.2014.08.058
DP  - Ovid Technologies
J2  - Psychiatry Res
KW  - Adolescent
KW  - Child
KW  - Child, Preschool
KW  - GABA Agents/ae [Adverse Effects]
KW  - *GABA Agents/tu [Therapeutic Use]
KW  - Humans
KW  - *Tourette Syndrome/dt [Drug Therapy]
KW  - Valproic Acid/ae [Adverse Effects]
KW  - *Valproic Acid/tu [Therapeutic Use]
KW  - 0 (GABA Agents)
KW  - 614OI1Z5WI (Valproic Acid)
L1  - internal-pdf://1212807001/Yang-2015-Sodium valproate for the treatment o.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Yang, Chun-Song Zhang, Ling-Li Lin, Yun-Zhu Guo, Qin S0165-1781(14)00755-0
PY  - 2015
SP  - 411-7
T2  - Psychiatry Research
TI  - Sodium valproate for the treatment of Tourette&#039;s syndrome in children: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25724485http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25724485&amp;id=doi:10.1016%2Fj.psychres.2014.08.058&amp;issn=0165-1781&amp;isbn=&amp;volume=226&amp;issue=2&amp;spage=411&amp;pages=411-7&amp;date=2015&amp;title=Psychiatry+Research&amp;atitle=Sodium+valproate+for+the+treatment+of+Tourette%27s+syndrome+in+children%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Yang&amp;pid=%3Cauthor%3EYang+CS%3C%2Fauthor%3E%3CAN%3E25724485%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0165178114007550/1-s2.0-S0165178114007550-main.pdf?_tid=75d99cf4-04d2-11e7-87a6-00000aab0f01&amp;acdnat=1489068942_53af4f8c0b07402d5232c64e57203c3a
VL  - 226
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The efficacy of dexmethylphenidate (d-MPH) has been proven in the treatment of children and adolescents with attention-deficit hyperactivity disorder (ADHD). 

**OBJECTIVE: **
The aim of this systematic review is to determine the efficacy, acceptability, and tolerability of d-MPH in child and adolescent ADHD. 

**METHODS:**
The searches of SCOPUS, MEDLINE, CINAHL, and Cochrane Controlled Trials Register were performed in February 2015. All randomized controlled trials of d-MPH versus placebo that were performed in children and adolescents with ADHD up to 18 years of age were included in the study. The efficacy was measured by using the pooled mean-endpoint or mean-changed scores of ADHD rating scales and the response rate. Acceptability and tolerability were measured by using the pooled rates of overall discontinuation and discontinuation due to adverse events, respectively. 

**RESULTS: **
A total of 1,124 children and adolescents diagnosed as having ADHD were included in this review. In a laboratory school setting, the pooled mean-change and mean-endpoint scores in the d-MPH-treated group were significantly greater than those of the placebo-treated group with standardized mean difference (95% confidence interval [CI]) of -1.20 (-1.73, -0.67), I (2)=95%. Additionally, the pooled mean-changed scores of the ADHD rating scales for teachers and parents in the d-MPH-treated group were significantly greater than that of the placebo-treated group with weighted mean difference (95% CI) of -13.01 (-15.97, -10.05), I (2)=0% and (95% CI) of -12.99 (-15.57, -10.42), I (2)=0%, respectively. The pooled response rate in the d-MPH-treated groups had a significance higher than that of the placebo-treated group. The rates of pooled overall discontinuation and discontinuation due to adverse events between the two groups were not significantly different. 

**CONCLUSION: **
Based on the findings in this review, it can be concluded that d-MPH medication is efficacious and tolerable in child and adolescent ADHD. However, the acceptability of d-MPH is no greater than that of the placebo. Further systematic studies may confirm these findings.
AD  - Maneeton, Narong. Department of Psychiatry, Faculty of Medicine, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand. Maneeton, Benchalak. Department of Psychiatry, Faculty of Medicine, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand. Woottiluk, Pakapan. Division of Psychiatric Nursing, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand. Suttajit, Sirijit. Department of Psychiatry, Faculty of Medicine, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand. Likhitsathian, Surinporn. Department of Psychiatry, Faculty of Medicine, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand. Charnsil, Chawanun. Department of Psychiatry, Faculty of Medicine, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand. Srisurapanont, Manit. Department of Psychiatry, Faculty of Medicine, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand.
AN  - 26648726
AU  - Maneeton
AU  - N.
AU  - B.
AU  - Maneeton
AU  - P.
AU  - Woottiluk
AU  - S.
AU  - Suttajit
AU  - S.
AU  - Likhitsathian
AU  - C.
AU  - Charnsil
AU  - M.
AU  - Srisurapanont
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2147/NDT.S91765
DP  - Ovid Technologies
J2  - Neuropsychiatr
L1  - internal-pdf://0117926069/Maneeton-2015-Comparative efficacy, acceptabil.pdf
LA  - English
N1  - Maneeton, Narong Maneeton, Benchalak Woottiluk, Pakapan Suttajit, Sirijit Likhitsathian, Surinporn Charnsil, Chawanun Srisurapanont, Manit ndt-11-2943
PY  - 2015
SP  - 2943-52
T2  - Neuropsychiatric Disease and Treatment
TI  - Comparative efficacy, acceptability, and tolerability of dexmethylphenidate versus placebo in child and adolescent ADHD: a meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26648726http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26648726&amp;id=doi:10.2147%2FNDT.S91765&amp;issn=1176-6328&amp;isbn=&amp;volume=11&amp;issue=&amp;spage=2943&amp;pages=2943-52&amp;date=2015&amp;title=Neuropsychiatric+Disease+%26+Treatment&amp;atitle=Comparative+efficacy%2C+acceptability%2C+and+tolerability+of+dexmethylphenidate+versus+placebo+in+child+and+adolescent+ADHD%3A+a+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Maneeton&amp;pid=%3Cauthor%3EManeeton+N%3C%2Fauthor%3E%3CAN%3E26648726%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.dovepress.com/getfile.php?fileID=28140
VL  - 11
ER  -
TY  - JOUR
AB  - **Objective **
The authors performed meta-analyses of randomized controlled trials to examine the effects of cognitive training on attention-deficit/hyperactivity disorder (ADHD) symptoms, neuropsychological deficits, and academic skills in children/adolescents with ADHD.

**Method** 
The authors searched Pubmed, Ovid, Web of Science, ERIC, and CINAHAL databases through May 18, 2014. Data were aggregated using random-effects models. Studies were evaluated with the Cochrane risk of bias tool.

**Results **
Sixteen of 695 nonduplicate records were analyzed (759 children with ADHD). When all types of training were considered together, there were significant effects on total ADHD (standardized mean difference [SMD] = 0.37, 95% CI = 0.09-0.66) and inattentive symptoms (SMD = 0.47, 95% CI = 0.14-0.80) for reports by raters most proximal to the treatment setting (i.e., typically unblinded). These figures decreased substantially when the outcomes were provided by probably blinded raters (ADHD total: SMD = 0.20, 95% CI = 0.01-0.40; inattention: SMD = 0.32, 95% CI = -0.01 to 0.66). Effects on hyperactivity/impulsivity symptoms were not significant. There were significant effects on laboratory tests of working memory (verbal: SMD = 0.52, 95% CI = 0.24-0.80; visual: SMD = 0.47, 95% CI = 0.23-0.70) and parent ratings of executive function (SMD = 0.35, 95% CI = 0.08-0.61). Effects on academic performance were not statistically significant. There were no effects of working memory training, specifically on ADHD symptoms. Interventions targeting multiple neuropsychological deficits had large effects on ADHD symptoms rated by most proximal assessors (SMD = 0.79, 95% CI = 0.46-1.12). 

**Conclusion **
Despite improving working memory performance, cognitive training had limited effects on ADHD symptoms according to assessments based on blinded measures. Approaches targeting multiple neuropsychological processes may optimize the transfer of effects from cognitive deficits to clinical symptoms.
AD  - (Cortese, Stevenson, Sonuga-Barke) Developmental Brain-Behaviour Laboratory, Psychology Institute for Disorders of Impulse and Attention, University of Southampton, Highfield Campus SO17 1BJ, United Kingdom (Cortese, Daley) School of Medicine, University of Nottingham, United Kingdom (Cortese) New York University Child Study Center, New York, NY, United States (Sonuga-Barke) Ghent University, Belgium (Sonuga-Barke) Aarhus University, Denmark (Ferrin, Santosh, Stringaris) King&#039;s College London, Institute of Psychiatry, United Kingdom (Ferrin) Centro de Salud Mental de Estella, Navarra, Spain (Ferrin) Huntercombe Hospital Maidenhead, United Kingdom (Brandeis, Dittmann) Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Germany (Brandeis) University of Zurich, Switzerland (Buitelaar) Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre, Nijmegen, Netherlands (Buitelaar) Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, Netherlands (Holtmann) LWL-University Hospital for Child and Adolescent Psychiatry, Ruhr University, Bochum, Germany (Zuddas) Unit of Child Neuropsychiatry, University of Cagliari, Cagliari, Italy (Daley) Centre for ADHD and Neurodevelopmental Disorders Across the Lifespan, Institute of Mental Health, University of Nottingham, United Kingdom E.J.S. Sonuga-Barke, Developmental Brain-Behaviour Laboratory, Psychology Institute for Disorders of Impulse and Attention, University of Southampton, Highfield Campus SO17 1BJ, United Kingdom
AN  - 2015779330
AU  - Cortese,
AU  - S.
AU  - Ferrin,
AU  - M.
AU  - Brandeis,
AU  - D.
AU  - Buitelaar,
AU  - J.
AU  - Daley,
AU  - D.
AU  - Dittmann,
AU  - R.
AU  - W.
AU  - Holtmann,
AU  - M.
AU  - Santosh,
AU  - P.
AU  - Stevenson,
AU  - J.
AU  - Stringaris,
AU  - A.
AU  - Zuddas,
AU  - A.
AU  - Sonuga-Barke,
AU  - E.
AU  - J.
AU  - S.
DA  - 01 Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2014.12.010
DP  - Ovid Technologies
KW  - adhd evidence-based psychiatry executive functions nonpharmacological working memory attention attention deficit disorder/th [Therapy] child childhood disease/th [Therapy] cognition cognitive therapy controlled study executive function human meta analys
L1  - internal-pdf://3486813382/Cortese-2015-Cognitive training for attention-.pdf
LA  - English
M3  - Review
PY  - 2015
SP  - 164-174
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Cognitive training for attention-deficit/hyperactivity disorder: Meta-analysis of clinical and neuropsychological outcomes from randomized controlled trials
UR  - http://www.jaacap.com
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed13&amp;AN=2015779330
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jaac.2014.12.010&amp;issn=0890-8567&amp;isbn=&amp;volume=54&amp;issue=3&amp;spage=164&amp;pages=164-174&amp;date=2015&amp;title=Journal+of+the+American+Academy+of+Child+and+Adolescent+Psychiatry&amp;atitle=Cognitive+training+for+attention-deficit%2Fhyperactivity+disorder%3A+Meta-analysis+of+clinical+and+neuropsychological+outcomes+from+randomized+controlled+trials&amp;aulast=Cortese&amp;pid=%3Cauthor%3ECortese+S.%3C%2Fauthor%3E%3CAN%3E2015779330%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3Ehttp://ac.els-cdn.com/S0890856714008892/1-s2.0-S0890856714008892-main.pdf?_tid=2e10981c-1674-11e5-9120-00000aab0f6c&amp;acdnat=1434712575_79692a8f5b5eb3fe4ab4374960e953b8
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382075/pdf/main.pdf
VL  - 54
ER  -
TY  - JOUR
AB  - Large numbers of children over the world experience foster care each year. 

How best to satisfy their developmental needs and how to avoid placement breakdowns and negative consequences of foster care are important challenges. In this study, a series of four meta-analyses is performed to examine the longitudinal developmental outcomes of children in foster care. 

The focus is on adaptive functioning and behavioral outcomes. A literature search identified 11 studies suitable for inclusion in the meta-analysis on adaptive functioning (N=1,550), 24 studies for the meta-analysis on internalizing problems (N=1,984), 21 studies for the meta-analysis on externalizing problems (N=1,729) and 25 studies for the meta-analysis on total behavior problems (N=2,523). 

No overall improvement or deterioration was found for adaptive functioning. However, studies with a timespan longer than one year and studies with larger sample sizes showed development toward more negative adaptive functioning than studies with shorter timespans or smaller samples. No overall increases or decreases in internalizing, externalizing or total behavior problems were found. 

Based on these results, it is concluded that foster care does not negatively or positively affect foster children&#039;s developmental trajectories. Given that many children enter foster care with problems, this is a worrying situation. Further longitudinal research to find the factors necessary for improving foster children&#039;s developmental chances is recommended. 

Furthermore, routine screening and targeted foster-care interventions are adviseable to ensure that all children, who cannot be raised by their own parents, receive the support conducive to their positive development. 

Copyright &copy; 2015 Elsevier Ltd. All rights reserved.
AD  - Goemans, Anouk. Institute of Education and Child Studies, Leiden University, Wassenaarseweg 52, 2333 AK Leiden, The Netherlands. van Geel, Mitch. Institute of Education and Child Studies, Leiden University, Wassenaarseweg 52, 2333 AK Leiden, The Netherlands. Vedder, Paul. Institute of Education and Child Studies, Leiden University, Wassenaarseweg 52, 2333 AK Leiden, The Netherlands.
AN  - 25724659
AU  - Goemans,
AU  - A.
AU  - van
AU  - Geel,
AU  - A.
AU  - Vedder,
AU  - P.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.chiabu.2015.02.003
DP  - Ovid Technologies
J2  - Child Abuse Negl
KW  - Adaptation, Psychological
KW  - Adolescent
KW  - Child
KW  - Child Behavior Disorders/px [Psychology]
KW  - *Child Development
KW  - Child, Preschool
KW  - *Foster Home Care/td [Trends]
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - Longitudinal Studies
KW  - Time Factors
L1  - internal-pdf://0049541756/Goemans-2015-Over three decades of longitudina.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Goemans, Anouk van Geel, Mitch Vedder, Paul S0145-2134(15)00048-4
PY  - 2015
SP  - 121-34
T2  - Child Abuse &amp; Neglect
TI  - Over three decades of longitudinal research on the development of foster children: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25724659http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25724659&amp;id=doi:10.1016%2Fj.chiabu.2015.02.003&amp;issn=0145-2134&amp;isbn=&amp;volume=42&amp;issue=&amp;spage=121&amp;pages=121-34&amp;date=2015&amp;title=Child+Abuse+%26+Neglect&amp;atitle=Over+three+decades+of+longitudinal+research+on+the+development+of+foster+children%3A+a+meta-analysis.&amp;aulast=Goemans&amp;pid=%3Cauthor%3EGoemans+A%3C%2Fauthor%3E%3CAN%3E25724659%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0145213415000484/1-s2.0-S0145213415000484-main.pdf?_tid=533bb03e-04c7-11e7-ad26-00000aab0f26&amp;acdnat=1489064160_7bfe40d0c6c9463a03d602ff4e8ecc64
VL  - 42
ER  -
TY  - JOUR
AB  - **Objectives: **
This paper aimed to systematically evaluate the mental health and well-being outcomes observed in previous community-based obesity prevention interventions in adolescent populations.

**Setting: **
Systematic review of literature from database inception to October 2014. Articles were sourced from CINAHL, Global Health, Health Source: Nursing and Academic Edition, MEDLINE, PsycARTICLES and PsycINFO, all of which were accessed through EBSCOhost. The Cochrane Database was also searched to identify all eligible articles. PRISMA guidelines were followed and search terms and search strategy ensured all possible studies were identified for review. 

**Participants: **
Intervention studies were eligible for inclusion if they were: focused on overweight or obesity prevention, community-based, targeted adolescents (aged 10-19 years), reported a mental health or well-being measure, and included a comparison or control group. Studies that focused on specific adolescent groups or were treatment interventions were excluded from review. Quality of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) guidelines. 

**Primary and secondary outcome measures: **
Primary outcomes were measures of mental health and well-being, including diagnostic and symptomatic measures. Secondary outcomes included adiposity or weight-related measures. 

**Results: **
Seven studies met the inclusion criteria; one reported anxiety/depressive outcomes, two reported on self-perception well-being measures such as self-esteem and self-efficacy, and four studies reported outcomes of quality of life. Positive mental health outcomes demonstrated that following obesity prevention, interventions included a decrease in anxiety and improved health-related quality of life. Quality of evidence was graded as very low. 

**Conclusions: **
Although positive outcomes for mental health and well-being do exist, controlled evaluations of community-based obesity prevention interventions have not often included mental health measures (n=7). It is recommended that future interventions incorporate mental health and well-being measures to identify any potential mechanisms influencing adolescent weight-related outcomes, and equally to ensure interventions are not causing harm to adolescent mental health.
AD  - [Hoare, Erin; Millar, Lynne] Deakin Univ, Sch Hlth &amp; Social Dev, Geelong, Vic 3217, Australia. [Hoare, Erin; Millar, Lynne; Nichols, Melanie; Allender, Steven] Deakin Univ, WHO Collaborating Ctr Obes Prevent, Burwood, Vic, Australia. [Fuller-Tyszkiewicz, Matthew; Skouteris, Helen] Deakin Univ, Sch Psychol, Burwood, Vic, Australia. Hoare, E (reprint author), Deakin Univ, Sch Hlth &amp; Social Dev, Geelong, Vic 3217, Australia. ejhoa@deakin.edu.au
AN  - WOS:000348171800038
AU  - Hoare,
AU  - E.
AU  - Fuller-Tyszkiewicz,
AU  - M.
AU  - Skouteris,
AU  - H.
AU  - Millar,
AU  - L.
AU  - Nichols,
AU  - M.
AU  - Allender,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1136/bmjopen-2014-006586
J2  - BMJ Open
KW  - randomized controlled-trial
KW  - quality-of-life
KW  - school-based intervention
KW  - body-mass index
KW  - physical-activity
KW  - childhood obesity
KW  - weight-loss
KW  - self-esteem
KW  - program
KW  - overweight
KW  - General &amp; Internal Medicine
L1  - internal-pdf://1602225277/e006586.full.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AZ4DH Times Cited: 1 Cited Reference Count: 76 Hoare, Erin Fuller-Tyszkiewicz, Matthew Skouteris, Helen Millar, Lynne Nichols, Melanie Allender, Steven Australian National Health and Medical Research Council/Australian National Heart Foundation Career Development Fellowship [APP1045836]; US National Institutes of Health [1R01HL115485-01A1]
PY  - 2015
SP  - 13
T2  - Bmj Open
TI  - Systematic review of mental health and well-being outcomes following community-based obesity prevention interventions among adolescents
UR  - &lt;Go to ISI&gt;://WOS:000348171800038
VL  - 5
ER  -
TY  - JOUR
AB  - **Background: **
Previous meta-analyses of paediatric obsessive-compulsive disorder (OCD) have shown much higher effect size for standard individual cognitive behaviour therapy (SI-CBT) compared with control conditions than for serotonin reuptake inhibitors (SRIs) compared with placebo. Other factors, such as systematic differences in the provided care or exposure to factors other than the interventions of interest (performance bias) may be stronger confounders in psychotherapy research than in pharmacological research. 

**Aims: **
These facts led us to review SI-CBT studies of paediatric OCD with the aim to compare the effect estimates across different comparisons, including active treatments. 

**Method: **
We included only randomized controlled trials (RCTs) or cluster RCTs with treatment periods of 12-16 weeks. Outcome was post-test score on the Children&#039;s Yale-Brown Obsessive Compulsive Scale (CYBOCS). 

**Results: **
Thirteen papers reporting from 13 RCTs with 17 comparison conditions were included. SI-CBT was superior to wait-list and placebo therapy but not active treatments. Effect estimates for SI-CBT in wait-list comparison studies were significantly larger than in placebo-therapy comparison studies. In addition, the SI-CBT effect estimate was not significantly different when compared with SRIs alone or combined SRIs and CBT. 

**Conclusions:** 
Performance bias may have inflated previous effect estimates for SI-CBT when comparison contingencies included wait-list. However, the calculated SI-CBT effect estimate was lower but significant when compared with placebo therapy. The effects of SI-CBT and active treatments were not significantly different. In conclusion, our data support the current clinical guidelines, although better comparisons between SI-CBT and SRIs are needed.
AD  - [Skarphedinsson, Gudmundur; Hanssen-Bauer, Ketil; Kornor, Hege; Axelsdottir, Brynhildur; Biedilae, Solvi; Ivarsson, Tord] Eastern &amp; Southern Norway, Ctr Child &amp; Adolescent Mental Hlth, N-0405 Oslo, Norway. [Heiervang, Einar R.] Oslo Univ Hosp, Dept Mental Hlth &amp; Addict, Oslo, Norway. [Landro, Nils Inge] Univ Oslo, Dept Psychol, Clin Neurosci Res Grp, Oslo, Norway. Skarphedinsson, G (reprint author), Eastern &amp; Southern Norway, Ctr Child &amp; Adolescent Mental Hlth, POB 4623 Nydalen, N-0405 Oslo, Norway. gudmundr@gmail.com
AN  - WOS:000346904900001
AU  - Skarphedinsson,
AU  - G.
AU  - Hanssen-Bauer,
AU  - K.
AU  - Kornor,
AU  - H.
AU  - Heiervang,
AU  - E.
AU  - R.
AU  - Landro,
AU  - N.
AU  - I.
AU  - Axelsdottir,
AU  - B.
AU  - Biedilae,
AU  - S.
AU  - Ivarsson,
AU  - T.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3109/08039488.2014.941395
J2  - Nord. J. Psychiatr.
KW  - Child and adolescent Cognitive behaviour therapy Comparison Meta-analysis Obsessive-compulsive disorder Outcome Paediatric Placebo Psychotherapy Wait-list RANDOMIZED CONTROLLED-TRIAL META-ANALYSIS FUNCTIONAL IMPAIRMENT FAMILY TREATMENT OUTCOME RESEARCH
L1  - internal-pdf://1564513300/Skarphedinsson-2015-Standard individual cognit.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AX4LU Times Cited: 0 Cited Reference Count: 71 Skarphedinsson, Gudmundur Hanssen-Bauer, Ketil Kornor, Hege Heiervang, Einar R. Landro, Nils Inge Axelsdottir, Brynhildur Biedilae, Solvi Ivarsson, Tord INFORMA HEALTHCARE LONDON NORD J PSYCHIAT
PY  - 2015
SP  - 81-92
T2  - Nordic Journal of Psychiatry
TI  - Standard individual cognitive behaviour therapy for paediatric obsessive-compulsive disorder: A systematic review of effect estimates across comparisons
UR  - &lt;Go to ISI&gt;://WOS:000346904900001http://informahealthcare.com/doi/pdfplus/10.3109/08039488.2014.941395
UR  - http://www.tandfonline.com/doi/pdf/10.3109/08039488.2014.941395?needAccess=true
VL  - 69
ER  -
TY  - JOUR
AB  - **Background:** 
Infants in the neonatal intensive care unit (NICU) are subjected to stress, including sound of high intensity. The sound environment in the NICU is louder than most home or office environments and contains disturbing noises of short duration and at irregular intervals. There are competing auditory signals that frequently challenge preterm infants, staff and parents. The sound levels in NICUs often exceed the maximum acceptable level of 45 decibels (dB), recommended by the American Academy of Pediatrics. Hearing impairment is diagnosed in 2% to 10% of preterm infants versus 0.1% of the general paediatric population. Noise may cause apnoea, hypoxaemia, alternation in oxygen saturation, and increased oxygen consumption secondary to elevated heart and respiratory rates and may, therefore, decrease the amount of calories available for growth. Elevated levels of speech are needed to overcome the noisy environment in the NICU, thereby increasing the negative impacts on staff, newborns, and their families. High noise levels are associated with an increased rate of errors and accidents, leading to decreased performance among staff. The aim of interventions included in this review is to reduce sound levels to 45 dB or less. This can be achieved by lowering the sound levels in an entire unit, treating the infant in a section of a NICU, in a &#039;private&#039; room, or in incubators in which the sound levels are controlled, or reducing the sound levels that reaches the individual infant by using earmuffs or earplugs. By lowering the sound levels that reach the neonate, the resulting stress on the cardiovascular, respiratory, neurological, and endocrine systems can be diminished, thereby promoting growth and reducing adverse neonatal outcomes.

**Objectives:** 
Primary objectiveTo determine the effects of sound reduction on growth and long-term neurodevelopmental outcomes of neonates. Secondary objectives1. To evaluate the effects of sound reduction on short-term medical outcomes (bronchopulmonary dysplasia, intraventricular haemorrhage, periventricular leukomalacia, retinopathy of prematurity).2. To evaluate the effects of sound reduction on sleep patterns at three months of age.3. To evaluate the effects of sound reduction on staff performance.4. To evaluate the effects of sound reduction in the neonatal intensive care unit (NICU) on parents&#039; satisfaction with the care.

**Search methods:** 
We searched the Cochrane Central Register of Controlled Trials (The Cochrane Library), MEDLINE, EMBASE, CINAHL, abstracts from scientific meetings, clinical trials registries (clinicaltrials.gov; controlled-trials.com; and who.int/ictrp), Pediatric Academic Societies Annual meetings 2000 to 2014 (Abstracts2ViewTM), reference lists of identified trials, and reviews to November 2014.Selection criteria: Preterm infants (&lt; 32 weeks&#039; postmenstrual age (PMA) or &lt; 1500 g birth weight) cared for in the resuscitation area, during transport, or once admitted to a NICU or a stepdown unit.

**Data collection and analysis:** 
We performed data collection and analyses according to the Cochrane Neonatal Review Group.

**Main results:** 
One small, high quality study assessing the effects of silicone earplugs versus no earplugs qualified for inclusion. The original inclusion criteria in our protocol stipulated an age of &lt; 48 hours at the time of initiating sound reduction. We made a deviation from our protocol and included this study in which some infants would have been &gt; 48 hours old. There was no significant difference in weight at 34 weeks postmenstrual age (PMA): mean difference (MD) 111 g (95% confidence interval (CI) -151 to 374 g) (n = 23). There was no significant difference in weight at 18 to 22 months corrected age between the groups: MD 0.31 kg, 95% CI -1.53 to 2.16 kg (n = 14). There was a significant difference in Mental Developmental Index (Bayley II) favouring the silicone earplugs group at 18 to 22 months corrected age: MD 14.00, 95% CI 3.13 to 24.87 (n = 12), but not for Psychomotor Development Index (Bayley II) at 18 to 22 months corrected age: MD -2.16, 95% C 18.44 to 14.12 (n =12).

**Authors&#039; conclusions:** 
To date, only 34 infants have been enrolled in a randomised controlled trial (RCT) testing the effectiveness of reducing sound levels that reach the infants&#039; ears in the NICU. Based on the small sample size of this single trial, we cannot make any recommendations for clinical practice. Larger, well designed, conducted and reported trials are needed.
AN  - CD010333
AU  - Almadhoob,
AU  - A.
AU  - Ohlsson,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd010333.pub2
KW  - Neonatal
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Sound reduction management in the neonatal intensive care unit for preterm or very low birth weight infants
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD010333.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD010333.pub2/asset/CD010333.pdf?v=1&amp;t=iw7l71bf&amp;s=1b55cf5d2ba8cd0d6c4c489c14e874e53f51dee9
ER  -
TY  - JOUR
AB  - **Background:** 
This is an updated version of an original Cochrane review published in Issue 3 2006 (Perry 2006). The review represents one from a family of four reviews focusing on interventions for drug-using offenders. This specific review considers interventions aimed at reducing drug use or criminal activity, or both for drug-using offenders with co-occurring mental illness.

**Objectives:** 
To assess the effectiveness of interventions for drug-using offenders with co-occurring mental illness in reducing criminal activity or drug use, or both.Search methods: We searched 14 electronic bibliographic databases up to May 2014 and 5 Internet resources (searched between 2004 and 11 November 2009). We contacted experts in the field for further information.

**Selection criteria:** 
We included randomised controlled trials designed to reduce, eliminate, or prevent relapse of drug use and criminal activity, or both in drug-using offenders with co-occurring mental illness. We also reported data on the cost and cost-effectiveness of interventions.

**Data collection and analysis:** 
We used standard methodological procedures expected by The Cochrane Collaboration.

**Main results:** 
Eight trials with 2058 participants met the inclusion criteria. The methodological quality of the trials was generally difficult to rate due to a lack of clear reporting. On most &#039;Risk of bias&#039; items, we rated the majority of studies as unclear. Overall, we could not statistically combine the results due to the heterogenous nature of the different study interventions and comparison groups. A narrative summary of the findings identified that the interventions reported limited success with reducing self report drug use, but did have some impact on re-incarceration rates, but not re-arrest. In the single comparisons, we found moderate-quality evidence that therapeutic communities determine a reduction in re-incarceration but reported less success for outcomes of re-arrest, moderate quality of evidence and self report drug use. Three single studies evaluating case management via a mental health drug court (very low quality of evidence), motivational interviewing and cognitive skills (low and very low quality of evidence) and interpersonal psychotherapy (very low quality of evidence) did not report significant reductions in criminal activity and self report drug use respectively. Quality of evidence for these three types of interventions was low to very low. The trials reported some cost information, but it was not sufficient to be able to evaluate the cost-effectiveness of the interventions.

**Authors&#039; conclusions:** 
Two of the five trials showed some promising results for the use of therapeutic communities and aftercare, but only in relation to reducing subsequent re-incarceration. Overall, the studies showed a high degree of variation, warranting a degree of caution in the interpretation of the magnitude of effect and direction of benefit for treatment outcomes. More evaluations are required to assess the effectiveness of interventions for drug-using offenders with co-occurring mental health problems.
AN  - CD010901
AU  - Perry,
AU  - A.
AU  - E.
AU  - Neilson,
AU  - M.
AU  - Martyn,
AU  - St-James,
AU  - M.
AU  - Glanville,
AU  - J.
AU  - M.
AU  - Woodhouse,
AU  - R.
AU  - Godfrey,
AU  - C.
AU  - Hewitt,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd010901.pub2
KW  - Case Management
KW  - Crime [prevention &amp; control] [statistics &amp; numerical data]
KW  - Diagnosis, Dual (Psychiatry)
KW  - Law Enforcement
KW  - Mental Disorders [therapy]
KW  - Motivational Interviewing
KW  - Psychotherapy
KW  - Randomized Controlled Trials as Topic
KW  - Substance-Related Disorders [therapy]
KW  - Therapeutic Community
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Young Adult[checkword]
KW  - Addictn
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for drug-using offenders with co-occurring mental illness
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD010901.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD010901.pub2/asset/CD010901.pdf?v=1&amp;t=iw7jtpj1&amp;s=68c4ac948feab801a841daf9e2e8791d9008fb74
ER  -
TY  - JOUR
AB  - **Objective: **
Selective serotonin reuptake inhibitors (SSRIs) are the first-line pharmacological treatment for pediatric major depressive disorder (MDD). We conducted a meta-analysis to examine the following: the time-course of response to SSRIs in pediatric depression; whether higher doses of SSRIs are associated with an improved response in pediatric depression; differences in efficacy between SSRI agents; and whether the time-course and magnitude of response to SSRIs is different in pediatric and adult patients with MDD. 

**Method: **
We searched PubMed and CENTRAL for randomized controlled trials comparing SSRIs to placebo for the treatment of pediatric MDD. We extracted weekly symptom data from trials to characterize the trajectory of pharmacological response to SSRIs. Pooled estimates of treatment effect were calculated based on standardized mean differences between treatment and placebo groups.

**Results: **
The meta-analysis included 13 pediatric MDD trials with a total of 3,004 patients. A logarithmic model indicating that the greatest benefits of SSRIs occurred early in treatment best fit the longitudinal data (log [week] = 0.10, 95% CI = 0.06-0.15, p &lt; .0001). There were no significant differences based on maximum SSRI dose or between particular SSRI agents. SSRIs were demonstrated to have a smaller benefit in pediatric compared to adult MDD. 

**Conclusion: **
Treatment gains in pediatric MDD are greatest early in treatment and are, on average, minimal after 4 weeks of SSRI pharmacotherapy in pediatric MDD. Further research is needed using individual patient data to examine the power of early SSRI response (e.g., 2-4 weeks) to predict outcomes in short-term pharmacological trials.
AD  - [Varigonda, Anjali L.] Univ Vermont, Med Ctr, Burlington, VT 05405 USA. [Jakubovski, Ewgeni; Coughlin, Catherine; Bloch, Michael H.] Yale Univ, Sch Med, Yale Child Study Ctr, New Haven, CT USA. [Bloch, Michael H.] Yale Univ, New Haven, CT 06520 USA. [Taylor, Matthew J.] Univ Oxford, Oxford OX1 2JD, England. [Freemantle, Nick] Univ Birmingham, Birmingham, W Midlands, England. Bloch, MH (reprint author), Yale Univ, Sch Med, Ctr Child Study, POB 2070900, New Haven, CT 06520 USA. michael.bloch@yale.edu
AN  - WOS:000356983100008
AU  - Varigonda,
AU  - A.
AU  - L.
AU  - Jakubovski,
AU  - E.
AU  - Taylor,
AU  - M.
AU  - J.
AU  - Freemantle,
AU  - N.
AU  - Coughlin,
AU  - C.
AU  - Bloch,
AU  - M.
AU  - H.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jaac.2015.05.004
J2  - J. Am. Acad. Child Adolesc. Psychiatr.
KW  - MDD
KW  - meta-analysis
KW  - serotonin reuptake inhibitors
KW  - placebo-controlled trial
KW  - randomized controlled-trials
KW  - double-blind
KW  - efficacy
KW  - adolescent depression
KW  - children
KW  - fluoxetine
KW  - antidepressants
KW  - paroxetine
KW  - childhood
KW  - escitalopram
KW  - Psychology
KW  - Pediatrics
KW  - Psychiatry
L1  - internal-pdf://3687374887/Varigonda-2015-Systematic Review and Meta-Anal.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: CL5ER Times Cited: 3 Cited Reference Count: 37 Varigonda, Anjali L. Jakubovski, Ewgeni Taylor, Matthew J. Freemantle, Nick Coughlin, Catherine Bloch, Michael H. National Institutes of Health/National Institute of Mental Health [1K23MH091240]; Trichotil-lomania Learning Center; Yale Child Study Center Research Training Program; APIRE/Eli Lilly and Co. Psychiatric Research Fellowship; AACAP/Eli Lilly and Co. Junior Investigator Award; NARSAD; National Center for Research Resources, a-component of the National Institutes of Health [UL1 RR024139]; NIH roadmap for Medical Research; Klingenstein Third Generation Foundation (KTGF); NIH; Trichotillomania Learning Center; Tourette Syndrome Association; Patterson Foundation; Rembrandt Foundation; American Academy of Child and Adolescent Psychiatry Research Initiative Junior Investigator Award The authors gratefully acknowledge support from the National Institutes of Health/National Institute of Mental Health (1K23MH091240), the Trichotil-lomania Learning Center, the Yale Child Study Center Research Training Program, the APIRE/Eli Lilly and Co. Psychiatric Research Fellowship, the AACAP/Eli Lilly and Co. Junior Investigator Award, NARSAD, and UL1 RR024139 from the National Center for Research Resources, a-component of the National Institutes of Health, and NIH roadmap for Medical Research.; The authors would like to thank the Klingenstein Third Generation Foundation (KTGF) for their support of the KTGF Medical Student National Conference in Child Psychiatry at which Dr. Varigonda and Dr Bloch first met and discussed work on this academic proiect; Dr. Bloch has received grant or research support from the NIH K23 Award, the Trichotillomania Learning Center, the Tourette Syndrome Association, the Patterson Foundation, NARSAD, the Rembrandt Foundation, and the American Academy of Child and Adolescent Psychiatry Research Initiative Junior Investigator Award Drs Varigonda, Taylor, Freemantle, Mr. Jakubovski, and Ms. Coughlin report no biomedical financial interests or potential conflicts of interest. 3 4 17 Elsevier science bv Amsterdam 1527-5418
PY  - 2015
SP  - 557-564
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Systematic Review and Meta-Analysis: Early Treatment Responses of Selective Serotonin Reuptake Inhibitors in Pediatric Major Depressive Disorder
UR  - &lt;Go to ISI&gt;://WOS:000356983100008
UR  - http://ac.els-cdn.com/S0890856715002932/1-s2.0-S0890856715002932-main.pdf?_tid=593a2c36-04d1-11e7-95c2-00000aab0f27&amp;acdnat=1489068465_d1be61868a309b83e1012e39c6f28d1c
VL  - 54
ER  -
TY  - JOUR
AB  - This review evaluates self-management literature targeting problem behaviors of primary school students in general education settings. 

Thirty-one single-case design studies met inclusion criteria, of which 16 demonstrated adequate methodological rigor, according to What Works Clearinghouse (WWC) design standards. 

Visual analysis and WWC replication standards were applied to determine whether self-management interventions can be classified as evidence based. 

Effect sizes were calculated using percentage of non-overlapping data. Results were analyzed at study and individual participant levels in terms of behavior outcomes, student disability and grade. 

Overall, results suggested there is sufficient research for self-management interventions to be classified as evidence-based practice for primary students with problem behaviors in regular classrooms. 

Interventions were effective across behaviors, disability categories, and grades. Gaps in the identified evidence base are identified and discussed. 

Additional high-quality research evidence is required to support applications of self-management for particular outcomes and student subgroups. Implications for future research and practice are discussed. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Busacca, Margherita L.: margherita.busacca@monash.edu; Anderson, Angelika: angelika.anderson@monash.edu; Moore, Dennis W.: dennis.moore@monash.edu Busacca, Margherita L.: Krongold Centre, Faculty of Education, Monash University, Building 5, Clayton Campus, Clayton, VIC, Australia, 3800, margherita.busacca@monash.edu Busacca, Margherita L.: Krongold Centre, Faculty of Education, Monash University, Clayton, VIC, Australia Anderson, Angelika: Krongold Centre, Faculty of Education, Monash University, Clayton, VIC, Australia Moore, Dennis W.: Krongold Centre, Faculty of Education, Monash University, Clayton, VIC, Australia
AN  - 2015-33076-001
AU  - Busacca,
AU  - M.
AU  - L.
AU  - Anderson,
AU  - A.
AU  - Moore,
AU  - D.
AU  - W.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10864-015-9230-3
DP  - Ovid Technologies
KW  - Self-management, Evidence-based practice, Single-case design systematic review, Primary school, Classroom behavior management
KW  - *Behavior Problems
KW  - *Classroom Behavior
KW  - *Self-Management
KW  - Intervention
KW  - Primary School Students
KW  - Special &amp; Remedial Education [3570]
KW  - Human Childhood (birth-12 yrs) Preschool Age (2-5 yrs)
L1  - internal-pdf://2797773650/Busacca-2015-Self-management for primary schoo.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2015
SP  - 373-401
T2  - Journal of Behavioral Education
TI  - Self-management for primary school students demonstrating problem behavior in regular classrooms: Evidence review of single-case design research
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-33076-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10864-015-9230-3&amp;issn=1053-0819&amp;isbn=&amp;volume=24&amp;issue=4&amp;spage=373&amp;pages=373-401&amp;date=2015&amp;title=Journal+of+Behavioral+Education&amp;atitle=Self-management+for+primary+school+students+demonstrating+problem+behavior+in+regular+classrooms%3A+Evidence+review+of+single-case+design+research.&amp;aulast=Busacca&amp;pid=%3Cauthor%3EBusacca%2C+Margherita+L%3C%2Fauthor%3E%3CAN%3E2015-33076-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s10864-015-9230-3
UR  - http://download.springer.com/static/pdf/817/art%253A10.1007%252Fs10864-015-9230-3.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10864-015-9230-3&amp;token2=exp=1489074444~acl=%2Fstatic%2Fpdf%2F817%2Fart%25253A10.1007%25252Fs10864-015-9230-3.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10864-015-9230-3*~hmac=7806cb59d403850c3eca7f3fac051e19dc42163ba53038e47c1dbd252a9b5299
VL  - 24
ER  -
TY  - JOUR
AB  - We evaluated the effectiveness of trauma-focused cognitive behavioral therapy (TF-CBT) for treating posttraumatic stress disorder and co-occurring depression symptoms across 21 between-group studies representing the data of 1,860 children and adolescents (1,106 girls and 754 boys). 

Separate meta-analytic procedures were conducted for studies that implemented wait-list/no treatment and alternative treatment comparisons to estimate aggregated treatment effect of TF-CBT and moderators of effect size magnitude. Limitations of our findings and implications for counselors are discussed. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Stephen Michelle Lenz, A. Stephen: stephen.lenz@tamucc.edu Lenz, A. Stephen: Early Childhood Education Center, Texas A&amp;M University Corpus Christi, Room 152, Corpus Christi, TX, US, 78412, stephen.lenz@tamucc.edu Lenz, A. Stephen: Early Childhood Education Center, Texas A&amp;M University-Corpus Christi, Corpus Christi, TX, US Hollenbaugh, K. Michelle: Early Childhood Education Center, Texas A&amp;M University-Corpus Christi, Corpus Christi, TX, US
AN  - 2015-20850-002
AU  - Lenz,
AU  - A.
AU  - Hollenbaugh,
AU  - K.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/2150137815573790
DP  - Ovid Technologies
KW  - TF-CBT, PTSD, depression, research
KW  - *Adolescent Development
KW  - *Cognitive Behavior Therapy
KW  - *Major Depression
KW  - *Posttraumatic Stress Disorder
KW  - *Treatment Effectiveness Evaluation
KW  - Comorbidity
KW  - Symptoms
KW  - Cognitive Therapy [3311]
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://2009347737/CORE Article- Lenz &amp; Hollenbaugh.pdf
LA  - English
M3  - Meta Analysis
PY  - 2015
SP  - 18-32
T2  - Counseling Outcome Research and Evaluation
TI  - Meta-analysis of trauma-focused cognitive behavioral therapy for treating PTSD and co-occurring depression among children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-20850-002http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F2150137815573790&amp;issn=2150-1378&amp;isbn=&amp;volume=6&amp;issue=1&amp;spage=18&amp;pages=18-32&amp;date=2015&amp;title=Counseling+Outcome+Research+and+Evaluation&amp;atitle=Meta-analysis+of+trauma-focused+cognitive+behavioral+therapy+for+treating+PTSD+and+co-occurring+depression+among+children+and+adolescents.&amp;aulast=Lenz&amp;pid=%3Cauthor%3ELenz%2C+A.+Stephen%3C%2Fauthor%3E%3CAN%3E2015-20850-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 6
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To assess effectiveness of school-based smoking prevention curricula keeping children never-smokers. DESIGN: Systematic review, meta-analysis. 

**DATA: **
MEDLINE (1966+), EMBASE (1974+), Cinahl, PsycINFO (1967+), ERIC (1982+), Cochrane CENTRAL, Health Star, Dissertation Abstracts, conference proceedings. 

**DATA SYNTHESIS: **
pooled analyses, fixed-effects models, adjusted ORs. Risk of bias assessed with Cochrane Risk of Bias tool. SETTING: 50 randomised controlled trials (RCTs) of school-based smoking curricula. 

**PARTICIPANTS: **
Never-smokers age 5-18 (n=143,495); follow-up &gt;=6 months; all countries; no date/language limitations. 

**INTERVENTIONS: **
Information, social influences, social competence, combined social influences/competence and multimodal curricula. 

**OUTCOME MEASURE: **
Remaining a never-smoker at follow-up. 

**RESULTS: **
Pooling all curricula, trials with follow-up &lt;=1 year showed no statistically significant differences compared with controls (OR 0.91 (0.82 to 1.01)), though trials of combined social competence/social influences curricula had a significant effect on smoking prevention (7 trials, OR 0.59 (95% CI 0.41 to 0.85)). Pooling all trials with longest follow-up showed an overall significant effect in favour of the interventions (OR 0.88 (0.82 to 0.95)), as did the social competence (OR 0.65 (0.43 to 0.96)) and combined social competence/social influences curricula (OR 0.60 (0.43 to 0.83)). No effect for information, social influences or multimodal curricula. Principal findings were not sensitive to inclusion of booster sessions in curricula or to whether they were peer-led or adult-led. Differentiation into tobacco-only or multifocal curricula had a similar effect on the primary findings. Few trials assessed outcomes by gender: there were significant effects for females at both follow-up periods, but not for males. 

**CONCLUSIONS: **
RCTs of baseline never-smokers at longest follow-up found an overall significant effect with average 12% reduction in starting smoking compared with controls, but no effect for all trials pooled at &lt;=1 year. However, combined social competence/social influences curricula showed a significant effect at both follow-up periods. 

**SYSTEMATIC REVIEW REGISTRATION: **
Cochrane Tobacco Review Group CD001293.
AN  - 25757946
AU  - Thomas,
AU  - R.
AU  - E.
AU  - McLellan,
AU  - J.
AU  - Perera,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmjopen-2014-006976
L1  - internal-pdf://3668888693/Thomas-2015-Effectiveness of school-based smok.pdf
PY  - 2015
SP  - e006976
T2  - BMJ Open
TI  - Effectiveness of school-based smoking prevention curricula: systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=25757946
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360839/pdf/bmjopen-2014-006976.pdf
VL  - 5
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To determine the effectiveness of psychological and/or educational interventions to prevent the onset of episodes of depression. 

**METHODS:**
Systematic review of systematic reviews and meta-analyses (SR/MA). We searched PubMed, PsycINFO, Cochrane Database of Systematic Reviews, OpenGrey, and PROSPERO from their inception until February 2014. Two reviewers independently evaluated the eligibility criteria of all SR/MA, abstracted data, and determined bias risk (AMSTAR). 

**RESULTS: **
Twelve SR/MA (156 non-repeated trials and 56,158 participants) were included. Of these, 142 (91%) were randomized-controlled, 13 (8.3%) controlled trials, and 1 (0.6%) had no control group. Five SR/MA focused on children and adolescents, four on specific populations (women after childbirth, of low socioeconomic status, or unfavorable circumstances; patients with severe traumatic physical injuries or stroke) and three addressed the general population. Nine (75%) SR/MA concluded that interventions to prevent depression were effective. Of the 156 trials, 137 (87.8%) reported some kind of effect size calculation. Effect sizes were small in 45 (32.8%), medium in 26 (19.1%), and large in 25 (18.2%) trials; 41 (29.9%) trials were not effective. Of the 141 trials for which follow-up periods were available, only 34 (24.1%) exceeded 12 months. 

**CONCLUSION: **
Psychological and/or educational interventions to prevent onset of episodes of depression were effective, although most had small or medium effect sizes. 

Copyright &copy; 2014. Published by Elsevier Inc.
AD  - Bellon, Juan Angel. Centro de Salud El Palo, Instituto de Investigacion Biomedica de Malaga (IBIMA), Unidad de Investigacion del Distrito de Atencion Primaria Malaga-Guadalhorce, Departamento de Medicina Preventiva y Salud Publica, Universidad de Malaga, Malaga, Spain. Electronic address: jabellon@uma.es. Moreno-Peral, Patricia. Instituto de Investigacion Biomedica de Malaga (IBIMA), Unidad de Investigacion del Distrito de Atencion Primaria Malaga-Guadalhorce, Malaga, Spain. Electronic address: predictmalaga@hotmail.com. Motrico, Emma. Departamento de Psicologia Psicologia y Trabajo Social, Universidad de Loyola, Sevilla, Spain. Electronic address: emotrico@uloyola.es. Rodriguez-Morejon, Alberto. Departamento de Personalidad, Evaluacion Tratamiento Psicologico, Universidad de Malaga, Malaga, Spain. Electronic address: aromore@uma.es. Fernandez, Ana. Centre for Disability Research Policy - Brain Mind Research Institute, Faculty of Health Sciences, University of Sydney, Sydney, Australia; Parc Sanitari Sant Joan de Deu, Fundacio Sant Joan de Deu, Barcelona, Spain. Electronic address: ana.fernandez@sydney.edu.au. Serrano-Blanco, Antoni. Parc Sanitari Sant Joan de Deu, Fundacio Sant Joan de Deu, Barcelona, Spain. Electronic address: aserrano@pssjd.org. Zabaleta-del-Olmo, Edurne. Institut Universitari d&#039;Investigacio en Atencio Primaria (IDIAP) Jordi Gol, Barcelona, Spain. Electronic address: ezabaleta@idiapjgol.org. Conejo-Ceron, Sonia. Instituto de Investigacion Biomedica de Malaga (IBIMA), Unidad de Investigacion del Distrito de Atencion Primaria Malaga-Guadalhorce, Malaga, Spain. Electronic address: soniafundacionimabis@hotmail.com.
AN  - 25445331
AU  - Bellon,
AU  - J.
AU  - A.
AU  - Moreno-Peral,
AU  - P.
AU  - Motrico,
AU  - E.
AU  - Rodriguez-Morejon,
AU  - A.
AU  - Fernandez,
AU  - A.
AU  - Serrano-Blanco,
AU  - A.
AU  - Zabaleta-del-Olmo,
AU  - E.
AU  - Conejo-Ceron,
AU  - S.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ypmed.2014.11.003
DP  - Ovid Technologies
J2  - Prev Med
KW  - Adolescent
KW  - Adult
KW  - Child
KW  - Depression/pc [Prevention &amp; Control]
KW  - *Depressive Disorder/pc [Prevention &amp; Control]
KW  - Female
KW  - Humans
KW  - Male
KW  - Meta-Analysis as Topic
KW  - *Primary Prevention/ed [Education]
KW  - *Psychotherapy/mt [Methods]
KW  - Review Literature as Topic
L1  - internal-pdf://3378614015/Bellon-2015-Effectiveness of psychological and.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Bellon, Juan Angel Moreno-Peral, Patricia Motrico, Emma Rodriguez-Morejon, Alberto Fernandez, Ana Serrano-Blanco, Antoni Zabaleta-del-Olmo, Edurne Conejo-Ceron, Sonia S0091-7435(14)00414-9
PY  - 2015
SP  - S22-32
T2  - Preventive Medicine
TI  - Effectiveness of psychological and/or educational interventions to prevent the onset of episodes of depression: A systematic review of systematic reviews and meta-analyses
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25445331http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25445331&amp;id=doi:10.1016%2Fj.ypmed.2014.11.003&amp;issn=0091-7435&amp;isbn=&amp;volume=76&amp;issue=&amp;spage=S22&amp;pages=S22-32&amp;date=2015&amp;title=Preventive+Medicine&amp;atitle=Effectiveness+of+psychological+and%2For+educational+interventions+to+prevent+the+onset+of+episodes+of+depression%3A+A+systematic+review+of+systematic+reviews+and+meta-analyses.&amp;aulast=Bellon&amp;pid=%3Cauthor%3EBellon+JA%3C%2Fauthor%3E%3CAN%3E25445331%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0091743514004149/1-s2.0-S0091743514004149-main.pdf?_tid=6e453aa8-04c2-11e7-ad26-00000aab0f26&amp;acdnat=1489062057_6b441d09bfb3dbe5dfcc3063f76dfc5f
VL  - 76 Suppl
ER  -
TY  - JOUR
AB  - **Bakgrunn** 
Mer enn halvparten av personene som sitter i fengsel i Norge har barn. Barn og unge med foreldre i fengsel kan ha økt risiko for dårlig psykisk helse og senere kriminell atferd. Disse emosjonelle og atferdsmessige problemene kan være forårsaket av faktorer knyttet til fengslingen i seg selv, for eksempel separasjonstraumer, stigmatisering og endringer i omsorg for barnet. I tillegg kan disse barna være utsatt for risikofaktorer for å utvikle problemer også før selve fengslingen, gjennom for eksempel lav utdannelse og mye konflikt innad i familien. Nasjonalt kunnskapssenter for helsetjenesten fikk i oppdrag av Kriminalomsorgsdirektoratet (KDI) å oppsummere tilgjengelig forskning om effekt av tiltak for å forebygge negative utfall for barn og unge med innsatte foreldre. Dette er viktig for å styrke mulighetene for å sette inn effektive tiltak for denne gruppen. Vi har oppsummert kvantitative effektstudier for å besvare følgende spørsmål: 1) Hvilken effekt har tiltak rettet mot foreldre i fengsel på å forebygge problemer hos barna og/eller forbedre foreldrenes holdninger og atferd i rollen som forelder? 2) Hvilken effekt har tiltak rettet mot barn med minst &eacute;n forelder i fengsel på å forebygge problemer hos barna? 

**Metode** 
Vi utførte et systematisk litteratursøk i relevante databaser med et avsluttende søk i februar 2013. I tillegg søkte vi i Google, referanselister og kontaktet fagpersoner. To personer gjennomgikk uavhengig av hverandre titler og sammendrag og deretter alle potensielt relevante artikler i fulltekst med følgende inklusjonskriterier: Populasjon: Foreldre eller barn (0 til 18 år) i familier med minst &eacute;n innsatt forelder. Intervensjon: Foreldreveiledningstiltak og alle typer tiltak rettet mot barn med minst &eacute;n forelder i fengsel. Kontroll: Ingen tiltak, venteliste og andre tiltak. Utfall: Alle typer utfall på foreldrene, familien og barna. Studiedesign: Alle studier med kontrollerte design. De inkluderte studiene ble kvalitetsvurdert av to personer uavhengig av hverandre. Kvaliteten på den samlede dokumentasjonen for hvert utfallsmål ble også vurdert. Prosjektleder hentet ut informasjon fra de inkluderte studiene og en av medforfatterne dobbeltsjekket dette. Vi oppsummerte resultatene i henhold til kriteriene i Kunnskapssenterets metodehåndbok. 

**Resultat og diskusjon** 
Totalt 22 studier fra 19 publikasjoner møtte inklusjonskriteriene. Studiene var utgitt i tidsrommet 1999-2011 og hadde til sammen 2500 deltakere. Alle studiene var utført i USA. I 14 av studiene var tiltaket rettet mot mødre, i seks studier var tiltaket rettet mot fedre og &eacute;n studie evaluerte tiltak rettet mot både mødre og fedre. Kun &eacute;n studie så på tiltak rettet mot barn (støttegrupper for barn med foreldre i fengsel). Studiedesignene i de inkluderte studiene var randomiserte kontrollerte studier (n=5) og ikke-randomiserte kontrollerte studier (n=17). De inkluderte studiene undersøkte effekt av tre typer tiltak: 1) Foreldreveiledning: kurs som handlet om oppdragelsesteknikker, kommunikasjons- og problemløsningsstrategier, kunnskap om barns utvikling og strategier for å håndtere separasjonen med barnet. I noen tilfeller bestod foreldreveiledning også av leketerapi som innebar samspill med barnet der foreldrene lekte med barnet og i tillegg fikk oppfølging og veiledning fra en terapeut. 2) Mødre-barn hjem (&laquo;Prison Nursery&raquo;): familiehus for innsatte mødre med nyfødte barn. Tiltaket innebar at kvinner bodde med barnet på mødre-barn hjem etter fødselen. De mottok i noen tilfeller også tilbud om veiledning angående relevante temaer for mødre (f.eks. ernæring og amming), familieplanlegging, jobb og rus. 3) Støttegrupper for barn: tiltak som handlet om samspillet mellom barna og hvordan de gjensidig kunne hjelpe og støtte hverandre. På bakgrunn av vår oppsummering av resultatene, og vurdering av kvaliteten på kunnskapsgrunnlaget, trekker vi følgende konklusjoner: &bull; Det er usikkert om foreldreveiledning har effekt på innsatte foreldres holdninger til- og atferd i rollen som forelder, og emosjonelle og atferdsmessige problemer hos barn med mor/far i fengsel. Kvaliteten på dokumentasjonen er vurdert til å være svært lav. &bull; Det er usikkert om mødre-barn hjem har effekt på innsatte mødres holdninger til- og atferd i rollen som mor, og emosjonelle og atferdsmessige problemer hos barn med mor i fengsel. Kvaliteten på dokumentasjonen er vurdert til å være svært lav. &bull; Det er usikkert om støttegrupper for barn kan redusere emosjonelle og atferdsmessige problemer hos barn med mor/far i fengsel. Kvaliteten på dokumentasjonen er vurdert til å være svært lav. De fleste av utfallsmålene angikk effekt av tiltakene på foreldrene. Kun fire av de 21 inkluderte studiene som undersøkte effekt av foreldreveiledning og mødre-barn hjem undersøkte effekt på barna. Imidlertid er det verdt å merke seg noen positive resultater: Enkeltstudier viste at mødre som fikk foreldreveiledning viste signifikant økning i kunnskap om oppdragelse, empati, aksept for barnet og mindre stress i forbindelse med besøk av barnet. I tillegg viste barna redusert problematferd. Fedre som fikk foreldreveiledning viste signifikant hyppigere kontakt med barna og redusert risiko for kriminelt tilbakefall. Flere av mødrene som hadde bodd på mødrebarn hjem var barnets omsorgsperson etter endt tiltak sammenlignet med kontrollmødrene. Det er usikkerhet knyttet til effekten av både foreldreveiledningstiltak for innsatte foreldre, mødre-barn-hjem og støttegrupper for barn med foreldre i fengsel. Denne usikkerheten skyldes at primærstudiene er små (få deltakere) og at de har risiko for systematiske skjevheter. Alle utfallene ble vurdert til å ha svært lav evidenskvalitet. Det er overraskende få kontrollerte studier som har evaluert tiltak for familier med mor/far i fengsel, med tanke på det høye antallet barn med foreldre i fengsel (særlig i USA) og dokumentasjonen om at disse barna er særlig sårbare for psykososiale og helsemessige vansker. Mangelen på effekstudier innenfor dette området må ses i lys av de forskningsetiske krav som stilles til å gjennomføre studier med sårbare grupper og at innsatte foreldre og deres barn er en vanskelig gruppe å gjennomføre store studier på der det er høy sannsynlighet for stort frafall. 

**Konklusjon** 
Denne systematiske oversikten peker på et behov for mer kunnskap om effekt av tiltak for innsatte foreldre og deres barn. Spesielt mangler det forskning på effekt av tiltak rettet mot barn. Kun &eacute;n av de inkluderte studiene evaluerte tiltak for barn. I tillegg hadde få av studiene om tiltak rettet mot foreldre undersøkt effekt på barnas helse og atferd. Det mangler også forskning på tiltak rettet mot innsatte foreldre og deres barn i en nordisk kontekst. Selv om man ikke kan trekke sikre konklusjoner om effekt av tiltakene som undersøkes i denne rapporten er det viktig å påpeke at dette ikke betyr at de ikke har effekt. Resultatene av tiltakene er for svakt dokumentert (svært lav) til at vi kan trekke konklusjoner om effekt.
AU  - Nilsen,
AU  - W.
AU  - Johansen,
AU  - S.
AU  - Blaasvær,
AU  - N.
AU  - Hammerstrøm,
AU  - K.
AU  - T.
AU  - Berg,
AU  - R.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/rapport_2015_15_foreldre-i-fengsel.pdf
PY  - 2015
T2  - Folkehelseinstituttet
TI  - Effekt av tiltak rettet mot innsatte foreldre og deres barn
ER  -
TY  - JOUR
AB  - Despite promising results from intensive formats of cognitive-behavioural therapy (CBT) for obsessive-compulsive disorder (OCD) the format is rarely used. 

The aim of the study was to systematically review the literature within this area of research and provide a meta-analysis of the effectiveness of intensive CBT for youths or adults with OCD. The meta-analysis was based on 17 trials (11 adult and 6 youth) including a total of 646 participants. Large overall pre-post effect sizes (ES) of 2.44 (95% CI 2.03-2.85) for clinical ratings (n = 16) and 1.23 (95% CI 1.01-1.45) for self-reports (n = 5) were found (Hedges g). 

Based on two comparative nonrandomized studies and one RCT, a larger post-treatment effect of intensive treatment compared to standard weekly or twice weekly CBT was found (between group ES = 0.39 (95% CI 0.05-0.74) for clinical ratings). 

This difference was no longer present at 3 month follow-up, mainly due to slight deterioration among patients who had received intensive CBT while patients from weekly conditions changed little. 

In sum, the meta-analysis indicates that intensive CBT is an effective treatment for youths and adults with OCD, and could be a promising format to enhance immediate treatment effects compared to standard CBT. Focus on how to maintain superior post-treatment effects of intensive CBT could be a promising research area. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Jonsson, Hjalti: hjonsson@health.sdu.dk Jonsson, Hjalti: Department of Psychology, University of Southern Denmark, Campusvej 55, Odense, Denmark, 5320, hjonsson@health.sdu.dk Jonsson, Hjalti: Anxiety Disorder Clinic for Children and Adolescents, Department of Psychology, Aarhus University, Aarhus, Denmark Kristensen, Maria: Anxiety Disorder Clinic for Children and Adolescents, Department of Psychology, Aarhus University, Aarhus, Denmark Arendt, Mikkel: Clinic for Anxiety and Obsessive Compulsive Disorders, Aarhus University Hospital, Risskov, Denmark
AN  - 2016-24904-012
AU  - Jonsson,
AU  - H.
AU  - Kristensen,
AU  - M.
AU  - Arendt,
AU  - M.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jocrd.2015.04.004
DP  - Ovid Technologies
KW  - Obsessive compulsive disorder, Meta-analysis, Cognitive behavioural therapy, Intensive treatment
KW  - *Cognitive Behavior Therapy
KW  - *Obsessive Compulsive Disorder
KW  - *Treatment Effectiveness Evaluation
KW  - Clinical Trials
KW  - Cognitive Therapy [3311]
KW  - Human Adulthood (18 yrs &amp; older)
L1  - internal-pdf://2544572640/1-s2.0-S2211364915000408-main.pdf
LA  - English
M3  - Meta Analysis
PY  - 2015
SP  - 83-96
T2  - Journal of Obsessive-Compulsive and Related Disorders
TI  - Intensive cognitive behavioural therapy for obsessive-compulsive disorder: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2016-24904-012http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jocrd.2015.04.004&amp;issn=2211-3649&amp;isbn=&amp;volume=6&amp;issue=&amp;spage=83&amp;pages=83-96&amp;date=2015&amp;title=Journal+of+Obsessive-Compulsive+and+Related+Disorders&amp;atitle=Intensive+cognitive+behavioural+therapy+for+obsessive-compulsive+disorder%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Jonsson&amp;pid=%3Cauthor%3EJonsson%2C+Hjalti%3C%2Fauthor%3E%3CAN%3E2016-24904-012%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 6
ER  -
TY  - JOUR
AB  - The current educational policy context in the United States necessitates that school-based programs prioritize students&#039; academic outcomes. 

This review examined the quantitative research on school mental health (SMH) early interventions and academic outcomes for at-risk high school students. Seven articles met the inclusion criteria for this review. All articles were examined according to study design and demographics, early intervention characteristics, and outcomes. 

Of the studies included, most were conducted in urban settings, involved the implementation of group-based early intervention strategies, and monitored GPA as a distal academic outcome. Counselors were frequent implementers of these early interventions. 

A meta-analysis found no statistically significant effect on the academic outcomes most commonly assessed in the studies (i.e., GPA, attendance, and discipline). Findings suggest the need for more rigorous research in this area. Implications for SMH early intervention research and practice are discussed. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Iachini, Aidyn L.: iachini@mailbox.sc.edu Iachini, Aidyn L.: College of Social Work, University of South Carolina, 123 DeSaussure, Columbia, SC, US, 29208, iachini@mailbox.sc.edu Iachini, Aidyn L.: College of Social Work, University of South Carolina, Columbia, SC, US Brown, Elizabeth Levine: College of Education and Human Development, George Mason University, Fairfax, VA, US Ball, Annahita: School of Social Work, College of Human Sciences and Education, Louisiana State University, Baton Rouge, LA, US Gibson, Jennifer E.: Department of Psychology, Xavier University, Cincinnati, OH, US Lize, Steven E.: College of Education and Human Development, George Mason University, Fairfax, VA, US
AN  - 2015-37126-004
AU  - Iachini,
AU  - A.
AU  - L.
AU  - Brown,
AU  - E.
AU  - L.
AU  - Ball,
AU  - A.
AU  - Gibson,
AU  - J.
AU  - E.
AU  - Lize,
AU  - S.
AU  - E.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/1754730X.2015.1044252
DP  - Ovid Technologies
KW  - early intervention, at-risk students, high school students, school mental health, academic outcomes, meta-analysis
KW  - *Academic Aptitude
KW  - *At Risk Populations
KW  - *Early Intervention
KW  - *High School Students
KW  - *School Based Intervention
KW  - Curriculum &amp; Programs &amp; Teaching Methods [3530]
KW  - Human
L1  - internal-pdf://4036367498/School mental health early interventions and a.pdf
LA  - English
M3  - Meta Analysis
PY  - 2015
SP  - 156-175
T2  - Advances in School Mental Health Promotion
TI  - School mental health early interventions and academic outcomes for at-risk high school students: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-37126-004http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F1754730X.2015.1044252&amp;issn=1754-730X&amp;isbn=&amp;volume=8&amp;issue=3&amp;spage=156&amp;pages=156-175&amp;date=2015&amp;title=Advances+in+School+Mental+Health+Promotion&amp;atitle=School+mental+health+early+interventions+and+academic+outcomes+for+at-risk+high+school+students%3A+A+meta-analysis.&amp;aulast=Iachini&amp;pid=%3Cauthor%3EIachini%2C+Aidyn+L%3C%2Fauthor%3E%3CAN%3E2015-37126-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 8
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Exercise has attracted attention as a potential helpful intervention in children with ADHD. Effects are emphasized on cognition, social-emotional, and motor development. 

**METHOD: **
A systematic literature search was conducted using the electronic databases Web of Science, PubMed, Scopus, and ERIC to analyze the efficacy of different types of exercise interventions in children and adolescents with ADHD. Seven studies examining the acute and 14 studies examining the long-term effects were included. 

**RESULTS:**
The largest effects were reported for mixed exercise programs on ADHD symptomatology and fine motor precision. However, because of the large differences in the study designs, the comparability is limited. 

**CONCLUSION: **
At that time, no evidence-based recommendation can be formulated regarding frequency, intensity, or duration of exercise. Nevertheless, some first trends regarding the effects of certain types of exercise can be identified. When focusing on long-term health benefits in children and adolescents with ADHD, qualitative exercise characteristics might play an important role. 

Copyright &copy; 2015 SAGE Publications.
AD  - Neudecker, Christina. Karlsruhe Institute of Technology, Germany christina.neudecker@kit.edu. Mewes, Nadine. Karlsruhe Institute of Technology, Germany. Reimers, Anne K. Karlsruhe Institute of Technology, Germany University of Konstanz, Germany. Woll, Alexander. Karlsruhe Institute of Technology, Germany.
AN  - 25964449
AU  - Neudecker,
AU  - C.
AU  - Mewes,
AU  - N.
AU  - Reimers,
AU  - A.
AU  - K.
AU  - Woll,
AU  - A.
DA  - May 11
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1087054715584053
DP  - Ovid Technologies
J2  - J Atten Disord
L1  - internal-pdf://1027969200/Neudecker-2015-Exercise Interventions in Child.pdf
LA  - English
N1  - Neudecker, Christina Mewes, Nadine Reimers, Anne K Woll, Alexander Using Smart Source Parsing May 1087054715584053
PY  - 2015
SP  - 11
T2  - Journal of Attention Disorders
TI  - Exercise Interventions in Children and Adolescents With ADHD: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=25964449http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25964449&amp;id=doi:10.1177%2F1087054715584053&amp;issn=1087-0547&amp;isbn=&amp;volume=&amp;issue=&amp;spage=&amp;pages=&amp;date=2015&amp;title=Journal+of+Attention+Disorders&amp;atitle=Exercise+Interventions+in+Children+and+Adolescents+With+ADHD%3A+A+Systematic+Review.&amp;aulast=Neudecker&amp;pid=%3Cauthor%3ENeudecker+C%3C%2Fauthor%3E%3CAN%3E25964449%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 11
ER  -
TY  - JOUR
AB  - **Background:** 
Sleep disturbance, including insomnia, is a major health issue among both adults and adolescents. Mindfulness-based interventions (MBIs) have recently received increased attention as a non-phannacological treatment option for patients with insomnia. 

**Objectives: **
This meta-analysis assesses the effects of MBIs on sleep disturbance in the general population. Methods: A literature search was conducted using PubMed, Medline, Psychlnfo, Google Scholar, and Cochrane library. The search terms were &quot;mindfulness therapy&quot;, &quot;mindfulness based cognitive therapy&quot;, &quot;mindfulness based stress reduction&quot;, &quot;acceptance and commitment therapy&quot;, and &quot;yoga&quot; crossed by &quot;insomnia&quot;, &quot;adults&quot;, &quot;adolescents&quot;, or &quot;children&quot;. All studies in English-language were examined through October 2013. Sixteen studies from different age groups were included in this meta-analysis. Sleep measurements were evaluated before and after MBIs, using both subjective as well as objective methods. Long-term effects were also examined. 

**Results:** 
The meta-analysis included 575 individuals across 16 studies. Ages ranged from 8-87 years and 82.09% of participants were female (472/575). MBIs were associated with increased sleep efficiency (SE; ES = 0.88; p &lt; 0.0001) and total sleep time (TST; ES = 0.47; p = 0.003) as assessed by sleep log. Additionally, wake after sleep onset and sleep onset latency decreased (WASO; ES = -0.84; p &lt; 0.0001; SOL; ES = -0.55; p &lt; 0.00001). Changes in sleep when measured by polysomnography and actigraphy, however, were not statistically significant. Sleep improvements as assessed by sleep log continued 2-6 months following treatment initiation. Interpretation is limited by the small number of studies on MBIs for insomnia, especially in adolescent populations. 

**Conclusion:** 
This meta-analysis suggests efficacy of mindfulness-based interventions for improving sleep, as assessed by subjective sleep logs but not by objective measures, and this continued several months after treatment initiation. More research is needed to explore this promising treatment option for adults and adolescents with insomnia. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Sedky, Karim: Sedky-Karim@Cooperhealth.edu Sedky, Karim: Department of Psychiatry, Cooper Medical School, Rowan University, 401 Haddon Avenue, Camden, NJ, US, 08103, Sedky-Karim@Cooperhealth.edu Kanen, Jonathan W.: Cooper Medical School, Rowan University, Camden, NJ, US Nazir, Racha: Thomas Jefferson University Hospital, Philadelphia, PA, US Sedky, Karim: Department of Psychiatry, Cooper Medical School, Rowan University, Camden, NJ, US Pradhan, Basant K.: Department of Psychiatry, Cooper Medical School, Rowan University, Camden, NJ, US
AN  - 2015-27099-005
AU  - Kanen,
AU  - J.
AU  - W.
AU  - Nazir,
AU  - R.
AU  - Sedky,
AU  - K.
AU  - Pradhan,
AU  - B.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2174/2210676605666150311222928
DP  - Ovid Technologies
KW  - Adolescents, cognitive behavioral therapy, mindfulness, meditation, yoga, insomnia
KW  - *Intervention
KW  - *Sleep Disorders
KW  - *Mindfulness
KW  - Insomnia
KW  - Polysomnography
KW  - Physical &amp; Somatoform &amp; Psychogenic Disorders [3290]
KW  - Specialized Interventions [3350]
KW  - Human Adolescence (13-17 yrs)
L1  - internal-pdf://2438077671/Mindfulness_AdolescentPsychiatry.pdf
LA  - English
M3  - Meta Analysis
PY  - 2015
SP  - 105-115
T2  - Adolescent Psychiatry
TI  - The effects of mindfulness-based interventions on sleep disturbance: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-27099-005http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.2174%2F2210676605666150311222928&amp;issn=2210-6766&amp;isbn=&amp;volume=5&amp;issue=2&amp;spage=105&amp;pages=105-115&amp;date=2015&amp;title=Adolescent+Psychiatry&amp;atitle=The+effects+of+mindfulness-based+interventions+on+sleep+disturbance%3A+A+meta-analysis.&amp;aulast=Kanen&amp;pid=%3Cauthor%3EKanen%2C+Jonathan+W%3C%2Fauthor%3E%3CAN%3E2015-27099-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 5
ER  -
TY  - JOUR
AB  - The present report synthesizes outcomes across meta-analyses of psychosocial (i.e., non-pharmacological) treatments for ADHD. 

A total of 12 meta-analyses were identified that met search criteria. The meta-analyses were notable in that there was surprisingly little overlap in studies included across them (range of overlap was 2-46 %). 

Further, there was considerable diversity across the meta-analyses in terms of the inclusion/exclusion criteria, types of psychosocial treatments reviewed, methodological characteristics, and magnitude of reported effect sizes, making it difficult to aggregate findings across meta-analyses or to investigate moderators of outcome. 

Effect sizes varied across the outcomes assessed, with meta-analyses reporting positive and significant effect sizes for measures of some areas of child impairment (e.g., social impairment) and small and more variable effect sizes for distal and/or untargeted outcomes (e.g., academic achievement). 

Results are reviewed in light of the larger literature on psychosocial interventions for ADHD, and specific recommendations for future meta-analyses of psychosocial treatments for ADHD are offered.
AD  - Fabiano,Gregory A. University at Buffalo, SUNY, 334 Diefendorf Hall, Buffalo, NY, 14214, USA, Fabiano@buffalo.edu.
AN  - 25691358
AU  - Fabiano,
AU  - G.
AU  - A.
AU  - Schatz,
AU  - N.
AU  - K.
AU  - Aloe,
AU  - A.
AU  - M.
AU  - Chacko,
AU  - A.
AU  - Chronis-Tuscano,
AU  - A.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10567-015-0178-6
DP  - Ovid Technologies
J2  - Clin Child Fam Psychol Rev
L1  - internal-pdf://3739688768/Fabiano-2015-A systematic review of meta-analy.pdf
LA  - English
N1  - Fabiano, Gregory A Schatz, Nicole K Aloe, Ariel M Chacko, Anil Chronis-Tuscano, Andrea R01 HD058588 (United States NICHD NIH HHS)
PY  - 2015
SP  - 77-97
T2  - Clinical Child and Family Psychology Review
TI  - A systematic review of meta-analyses of psychosocial treatment for attention-deficit/hyperactivity disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25691358 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25691358&amp;id=doi:10.1007%2Fs10567-015-0178-6&amp;issn=1096-4037&amp;isbn=&amp;volume=18&amp;issue=1&amp;spage=77&amp;pages=77-97&amp;date=2015&amp;title=Clinical+Child+%26+Family+Psychology+Review&amp;atitle=A+systematic+review+of+meta-analyses+of+psychosocial+treatment+for+attention-deficit%2Fhyperactivity+disorder.&amp;aulast=Fabiano&amp;pid=%3Cauthor%3EFabiano+GA%3C%2Fauthor%3E%3CAN%3E25691358%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10567-015-0178-6http://download.springer.com/static/pdf/465/art%253A10.1007%252Fs10567-015-0178-6.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10567-015-0178-6&amp;token2=exp=1435228854~acl=%2Fstatic%2Fpdf%2F465%2Fart%25253A10.1007%25252Fs10567-015-0178-6.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10567-015-0178-6*~hmac=638d386e325b82ba6a47289f5c344811b0a9fb887413008ff8316ea6f4ea135b
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346344/pdf/nihms-665323.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - Animals have a long history of inclusion in psychiatric treatment. There has been a recent growth in the empirical study of this practice, known as Animal-Assisted Intervention (AAI). We conducted a systematic review of the empirical literature on AAI for trauma, including posttraumatic stress disorder (PTSD). 

Ten studies qualified for inclusion, including six peer-reviewed journal articles and four unpublished theses. Participants were predominantly survivors of child abuse, in addition to military veterans. The presentation of AAI was highly variable across the studies. 

The most common animal species were dogs and horses. The most prevalent outcomes were reduced depression, PTSD symptoms, and anxiety. There was a low level of methodological rigor in most studies, indicating the preliminary nature of this area of investigation. 

We conclude that AAI may provide promise as a complementary treatment option for trauma, but that further research is essential to establish feasibility, efficacy, and manualizable protocols.
AD  - O&#039;Haire, Marguerite E. Center for the Human-Animal Bond, Center for Animal Welfare Science, Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University West Lafayette, IN, USA. Guerin, Noemie A. Center for the Human-Animal Bond, Center for Animal Welfare Science, Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University West Lafayette, IN, USA. Kirkham, Alison C. Center for the Human-Animal Bond, Center for Animal Welfare Science, Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University West Lafayette, IN, USA.
AN  - 26300817
AU  - O&#039;Haire,
AU  - M.
AU  - E.
AU  - Guerin,
AU  - N.
AU  - A.
AU  - Kirkham,
AU  - A.
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3389/fpsyg.2015.01121
DP  - Ovid Technologies
J2  - Front Psychol
L1  - internal-pdf://1101830256/O&#039;Haire-2015-Animal-Assisted Intervention for.pdf
LA  - English
M3  - Review
N1  - O&#039;Haire, Marguerite E Guerin, Noemie A Kirkham, Alison C
PY  - 2015
SP  - 1121
T2  - Frontiers in Psychology
TI  - Animal-Assisted Intervention for trauma: a systematic literature review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26300817http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26300817&amp;id=doi:10.3389%2Ffpsyg.2015.01121&amp;issn=1664-1078&amp;isbn=&amp;volume=6&amp;issue=&amp;spage=1121&amp;pages=1121&amp;date=2015&amp;title=Frontiers+in+Psychology&amp;atitle=Animal-Assisted+Intervention+for+trauma%3A+a+systematic+literature+review.&amp;aulast=O%27Haire&amp;pid=%3Cauthor%3EO%27Haire+ME%3C%2Fauthor%3E%3CAN%3E26300817%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528099/pdf/fpsyg-06-01121.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **BACKGROUND AND OBJECTIVE: **
Pediatric debilitating chronic pain is a severe health problem, often requiring complex interventions such as intensive interdisciplinary pain treatment (IIPT). Research is lacking regarding the effectiveness of IIPT for children. The objective was to systematically review studies evaluating the effects of IIPT. 

**METHODS:** 
Cochrane, Medline/Ovid, PsycInfo/OVID, PubMed, PubPsych, and Web of Science were searched. Studies were included if (1) treatment was coordinated by &gt;3 health professionals, (2) treatment occurred within an inpatient/day hospital setting, (3) patients were &lt;22 years, (4) patients experienced debilitating chronic pain, (5) the study was published in English, and (6) the study had &gt;10 participants at posttreatment. The child&#039;s pain condition, characteristics of the IIPT, and 5 outcome domains (pain intensity, disability, school functioning, anxiety, depressive symptoms) were extracted at baseline, posttreatment, and follow-up. 

**RESULTS: **
One randomized controlled trial and 9 nonrandomized treatment studies were identified and a meta-analysis was conducted separately on pain intensity, disability, and depressive symptoms revealing positive treatment effects. At posttreatment, there were large improvements for disability, and small to moderate improvements for pain intensity and depressive symptoms. The positive effects were maintained at short-term follow-up. Findings demonstrated extreme heterogeneity. 

**CONCLUSIONS: **
Effects in nonrandomized treatment studies cannot be attributed to IIPT alone. Because of substantial heterogeneity in measures for school functioning and anxiety, meta-analyses could not be computed. There is preliminary evidence for positive treatment effects of IIPT, but the small number of studies and their methodological weaknesses suggest a need for more research on IIPTs for children. 

Copyright &copy; 2015 by the American Academy of Pediatrics.
AD  - Hechler, Tanja. German Paediatric Pain Centre, Children&#039;s Hospital Datteln, Department of Children&#039;s Pain Therapy and Paediatric Palliative Care, Faculty of Health-School of Medicine, Witten/Herdecke University, Witten, Germany; t.hechler@deutsches-kinderschmerzzentrum.de. Kanstrup, Marie. Behavior Medicine Pain Treatment Services, Karolinska University Hospital, Stockholm, Sweden; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Holley, Amy Lewandowski. Division of Psychology, Institute on Development and Disability, Oregon Health and Science University, Portland, Oregon; Simons, Laura E. Boston Children&#039;s Hospital and Harvard Medical School, Boston, Massachusetts; and. Wicksell, Rikard. Behavior Medicine Pain Treatment Services, Karolinska University Hospital, Stockholm, Sweden; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Hirschfeld, Gerrit. German Paediatric Pain Centre, Children&#039;s Hospital Datteln, Department of Children&#039;s Pain Therapy and Paediatric Palliative Care, Faculty of Health-School of Medicine, Witten/Herdecke University, Witten, Germany; University of Applied Sciences, Osnabrueck, Osnabrueck, Germany. Zernikow, Boris. German Paediatric Pain Centre, Children&#039;s Hospital Datteln, Department of Children&#039;s Pain Therapy and Paediatric Palliative Care, Faculty of Health-School of Medicine, Witten/Herdecke University, Witten, Germany;
AN  - 26101358
AU  - Hechler,
AU  - T.
AU  - Kanstrup,
AU  - M.
AU  - Holley,
AU  - A.
AU  - L.
AU  - Simons.
AU  - L.
AU  - E.
AU  - Wicksell,
AU  - R.
AU  - Hirschfeld,
AU  - G.
AU  - Zernikow,
AU  - B.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2014-3319
DP  - Ovid Technologies
J2  - Pediatrics
KW  - Adolescent
KW  - *Anxiety/ep [Epidemiology]
KW  - Child
KW  - Child, Preschool
KW  - Chronic Pain/px [Psychology]
KW  - *Chronic Pain/th [Therapy]
KW  - *Depression/ep [Epidemiology]
KW  - *Disabled Children/px [Psychology]
KW  - Humans
KW  - *Pain Management/mt [Methods]
KW  - *Patient Care Team
L1  - internal-pdf://3720542999/Hechler-2015-Systematic Review on Intensive In.pdf
LA  - English
M3  - Review
N1  - Hechler, Tanja Kanstrup, Marie Holley, Amy Lewandowski Simons, Laura E Wicksell, Rikard Hirschfeld, Gerrit Zernikow, Boris peds.2014-3319
PY  - 2015
SP  - 115-27
T2  - Pediatrics
TI  - Systematic Review on Intensive Interdisciplinary Pain Treatment of Children With Chronic Pain
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26101358http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26101358&amp;id=doi:10.1542%2Fpeds.2014-3319&amp;issn=0031-4005&amp;isbn=&amp;volume=136&amp;issue=1&amp;spage=115&amp;pages=115-27&amp;date=2015&amp;title=Pediatrics&amp;atitle=Systematic+Review+on+Intensive+Interdisciplinary+Pain+Treatment+of+Children+With+Chronic+Pain.&amp;aulast=Hechler&amp;pid=%3Cauthor%3EHechler+T%3C%2Fauthor%3E%3CAN%3E26101358%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://pediatrics.aappublications.org/content/pediatrics/136/1/115.full.pdf
VL  - 136
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
There has been an increase in adolescent substance use that has led to the development and implementation of prevention programs. New evidence is needed in order to improve them and optimize the resources. The aim of this paper is to use a meta-analysis to analyze the effectiveness of school drug prevention programs in Spain. 

**METHOD: **
Twenty-one studies that evaluated drug abuse prevention programs in schools, were published between 2002 and 2013, and that met the selection criteria were identified. 

**RESULTS:**
Preventive program effectiveness was low ( d = 0.16), although it was higher at the follow-up ( d = 0.30). The programs were most effective in changing attitudes ( d = 0.44) towards drugs. The models of health education ( d = 0.48) and social learning ( d = 0.20) were also very effective, especially in combination with oral, written, and audiovisual support material ( d = 0.21) and the implementation of joint programs by health education professionals and faculty members ( d = 0.25). 

**CONCLUSIONS: **
Is possible to determine the need for more rigorous evaluations of interventions to establish useful programs.
AD  - Espada,Jose P. Universidad Miguel Hernandez.
AN  - 25633763
AU  - Espada,
AU  - J.
AU  - P.
AU  - Gonzalvez,
AU  - M.
AU  - T.
AU  - Orgiles,
AU  - M.
AU  - Lloret,
AU  - D.
AU  - Guillen-Riquelme,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.7334/psicothema2014.106
DP  - Ovid Technologies
J2  - Psicothema
L1  - internal-pdf://0755426024/Espada-2015-Meta-analysis of the effectiveness.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Espada, Jose P Gonzalvez, Maria T Orgiles, Mireia Lloret, Daniel Guillen-Riquelme, Alejandro
PY  - 2015
SP  - 5-12
T2  - Psicothema
TI  - Meta-analysis of the effectiveness of school substance abuse prevention programs in Spain
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25633763 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25633763&amp;id=doi:10.7334%2Fpsicothema2014.106&amp;issn=0214-9915&amp;isbn=&amp;volume=27&amp;issue=1&amp;spage=5&amp;pages=5-12&amp;date=2015&amp;title=Psicothema&amp;atitle=Meta-analysis+of+the+effectiveness+of+school+substance+abuse+prevention+programs+in+Spain.&amp;aulast=Espada&amp;pid=%3Cauthor%3EEspada+JP%3C%2Fauthor%3E%3CAN%3E25633763%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 27
ER  -
TY  - JOUR
AB  - The authors conducted a meta-analysis and systematic review that examined 23 studies evaluating the effectiveness of child centered play therapy (CCPT) conducted in elementary schools. 

Meta-analysis results were explored using a random effects model for mean difference and mean gain effect size estimates. 

Results revealed statistically significant effects for outcome constructs, including externalizing problems (d=0.34), internalizing problems (d=0.21), total problems (d=0.34), self-efficacy (d=0.29), academic (d=0.36), and other behaviors (d=0.38). 

Further, a systematic review was conducted on all studies compared with Outcome Research Coding Protocol criteria. Results indicated that CCPT studies provided quantitative support and qualitatively promising to strong evidence in support of its use in the schools.
AD  - [Ray, Dee C.] Univ N Texas, Denton, TX 76203 USA. [Armstrong, Stephen A.] Texas A&amp;M Univ, Commerce, TX USA. [Balkin, Richard S.] Univ Louisville, Louisville, KY 40292 USA. [Jayne, Kimberly M.] Univ New Mexico, Albuquerque, NM 87131 USA. Ray, DC (reprint author), Univ N Texas, Dept Counseling &amp; Higher Educ, 1155 Union Circle,Box 310829, Denton, TX 76203 USA. dee.ray@unt.edu
AN  - WOS:000348534500001
AU  - Ray,
AU  - D.
AU  - C.
AU  - Armstrong,
AU  - S.
AU  - A.
AU  - Balkin,
AU  - R.
AU  - S.
AU  - Jayne,
AU  - K.
AU  - M.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/pits.21798
J2  - Psychol. Schools
KW  - PSYCHOTHERAPY INTERVENTIONS EFFICACY Psychology, Educational
L1  - internal-pdf://1322933706/Ray-2015-CHILD-CENTERED PLAY THERAPY IN THE SC.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AZ9LA Times Cited: 0 Cited Reference Count: 65 Ray, Dee C. Armstrong, Stephen A. Balkin, Richard S. Jayne, Kimberly M. WILEY-BLACKWELL HOBOKEN PSYCHOL SCHOOLS
PY  - 2015
SP  - 107-123
T2  - Psychology in the Schools
TI  - Child-centered play therapy in schools: Review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000348534500001http://onlinelibrary.wiley.com/store/10.1002/pits.21798/asset/pits21798.pdf?v=1&amp;t=ib3kcr9q&amp;s=04cd9140f4d444e0ba0b10adf618d5288d972d30
UR  - http://onlinelibrary.wiley.com/store/10.1002/pits.21798/asset/pits21798.pdf?v=1&amp;t=j8yet9g2&amp;s=7aaf7381be29991d7e070374bc315c955b92e328
VL  - 52
ER  -
TY  - JOUR
AB  - The aim of this systematic review and meta-analysis was to synthesize the available evidence on embedded family therapy interventions in pediatrics and impacts on parental mental health and family functioning outcomes. 

The Cochrane Collaboration guidelines for systematic reviews and meta-analysis were used for this study. Six electronic databases were searched for randomized controlled trials and cluster randomized trials. The Cochrane Collaboration&#039;s Risk of Bias Tool and GRADE system were used to rate the quality of evidence of the included studies. 

The primary outcomes included parental distress, parental depressive symptoms, and dysfunctional parent-child interaction. Fixed effects models showed statistically significant reductions in parental distress at 6-month and 12-month post-intervention in favor of the intervention group. Family therapy model, intervention level, delivery modality, and dosage moderated intervention impacts on parental distress. 

Fixed effects models showed statistically significant reductions in parental depressive symptoms and in dysfunctional parent-child interaction in favor of the intervention group. Family therapy interventions can be successfully embedded in general pediatric primary care, and intended outcomes are achieved in this setting. Recommendations for future research and implications for policy development are discussed.
AD  - [Cluxton-Keller, Fallon; Riley, Anne W.; Noazin, Sassan; Umoren, Mfon Valencia] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Baltimore, MD 21218 USA. Cluxton-Keller, F (reprint author), Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Baltimore, MD 21218 USA. fcluxto1@jhu.edu
AN  - WOS:000364515000006
AU  - Cluxton-Keller,
AU  - F.
AU  - Riley,
AU  - A.
AU  - W.
AU  - Noazin,
AU  - S.
AU  - Umoren,
AU  - M.
AU  - V.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10567-015-0190-x
J2  - Clin. Child Fam. Psychol. Rev.
KW  - Systematic review
KW  - Family therapy
KW  - Integrated care
KW  - Pediatrics
KW  - oppositional-defiant-disorder
KW  - randomized controlled-trial
KW  - attention-deficit/hyperactivity-disorder
KW  - maternal depression
KW  - psychosocial problems
KW  - triple p
KW  - children
KW  - programs
KW  - outcomes
KW  - stress
KW  - Psychology
L1  - internal-pdf://3743264913/Cluxton-2015-Clinical Effectiveness of Family.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: CV8FB Times Cited: 0 Cited Reference Count: 74 Cluxton-Keller, Fallon Riley, Anne W. Noazin, Sassan Umoren, Mfon Valencia Johns Hopkins Bloomberg School of Public Health The authors gratefully acknowledge the Johns Hopkins University Welch Medical Library experts, Peggy Gross and Claire Twose, for devoting time and effort to developing the search syntax. The authors would like to thank the Johns Hopkins Bloomberg School of Public Health for providing financial support for data collection and qualitative analysis. The authors gratefully acknowledge Dhananjay Validya, Ph.D., for statistical assistance. 0 3 10 Springer/plenum publishers New york 1573-2827
PY  - 2015
SP  - 395-412
T2  - Clinical Child and Family Psychology Review
TI  - Clinical Effectiveness of Family Therapeutic Interventions Embedded in General Pediatric Primary Care Settings for Parental Mental Health: A Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000364515000006
UR  - https://link.springer.com/article/10.1007/s10567-015-0190-x
UR  - http://download.springer.com/static/pdf/425/art%253A10.1007%252Fs10567-015-0190-x.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10567-015-0190-x&amp;token2=exp=1489074032~acl=%2Fstatic%2Fpdf%2F425%2Fart%25253A10.1007%25252Fs10567-015-0190-x.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10567-015-0190-x*~hmac=0fadfe8ca410891827bc3bd69d27ac0a83cd7cb7cfda74c73a6872db63e4b1cd
VL  - 18
ER  -
TY  - JOUR
AB  - **STATEMENT OF THE PROBLEM: **
Refractory nocturnal enuresis possesses a heavy psychosocial burden for the affected child. Only a 15% spontaneous annual cure rate is reported. PURPOSE: This patient-level meta-analysis aimed to evaluate the efficacy of rapid palatal expansion to treat nocturnal enuresis among children. 

**MATERIALS AND METHOD: **
A sensitive search of electronic databases of PubMed (since 1966), SCOPUS (containing EMBASE, since 1980), Cochrane Central Register of Controlled Trials, CINAHL and EBSCO till Jan 2014 was performed. A set of regular terms was used for searching in data banks except for PubMed, for which medical subject headings (MeSH) keywords were used. Children aged at least six years old at the time of recruitment of either gender who underwent rapid palatal expansion and had attempted any type of pharmacotherapy prior to orthodontic intervention were included. 

**RESULTS: **
Six non-randomized clinical trials were found relevant, of which five studies had no control group. Eighty children were investigated with the mean age of 118 (28.12) months ranged from 74 to 185 months. The median time to become completely dry was 2.87 months [confidence interval (CI) 95% 2.07-2.93 months]. After one year, the average rate of becoming complete dry was 31%. The presence of posterior cross bite [relative risk (RR): 0.31, CI 95%: 0.12-0.79] and signs of upper respiratory obstruction during sleep (RR: 5.1, CI 95%: 1.44-18.04) significantly decreased and increased the chance of improvement, respectively. Meanwhile, the other predictors did not significantly predict the outcome after simultaneous adjustment in Cox regression model. 

**CONCLUSION: **
Rapid palatal expansion may be considered when other treatment modalities have failed. The 31% rate of cure is promising when compared to the spontaneous cure rate. Though, high-level evidence from the rigorous randomized controlled trials is scarce 

(Level of evidence: C).
AD  - Poorsattar-Bejeh Mir, Karim. Dept. of Pediatrics, Amir Mazandarani General Hospital, Mazandaran, Iran. Poorsattar-Bejeh Mir, Arash. Dental Materials Research Center, School of Dentistry, Babol University of Medical Sciences, Babol, Iran. Poorsattar-Bejeh Mir, Morvarid. Dept. of Orthodontics, University of Alabama, Birmingham, USA. Moradi-Lakeh, Maziar. Dept. of Community Medicine, Iran University of Medical Sciences, Tehran, Iran. Balmeh, Pouya. Undergraduate Student, School of Dentistry, Babol University of Medical Sciences, Babol, Iran. Nosrati, Kamran. Dept. of Maxillofacial Surgery, School of Dentistry, Babol University of Medical Sciences, Babol, Iran.
AN  - 26331141
AU  - Poorsattar-Bejeh
AU  - Mir,
AU  - K.
AU  - Poorsattar-Bejeh
AU  - Mir,
AU  - A.
AU  - Poorsattar-Bejeh
AU  - Mir,
AU  - M.
AU  - Moradi-Lakeh,
AU  - M.
AU  - Balmeh,
AU  - P.
AU  - Nosrati,
AU  - K.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pubmed/26331141
DP  - Ovid Technologies
J2  - J Dent (Shiraz)
L1  - internal-pdf://1701159757/jds-16-138.pdf
LA  - English
N1  - Poorsattar-Bejeh Mir, Karim Poorsattar-Bejeh Mir, Arash Poorsattar-Bejeh Mir, Morvarid Moradi-Lakeh, Maziar Balmeh, Pouya Nosrati, Kamran
PY  - 2015
SP  - 138-48
T2  - Journal of Dentistry
TI  - Rapid Palatal Expansion to Treat Nocturnal Enuretic Children: a Systematic Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26331141http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26331141&amp;id=doi:&amp;issn=2345-6485&amp;isbn=&amp;volume=16&amp;issue=3&amp;spage=138&amp;pages=138-48&amp;date=2015&amp;title=Journal+of+Dentistry&amp;atitle=Rapid+Palatal+Expansion+to+Treat+Nocturnal+Enuretic+Children%3A+a+Systematic+Review+and+Meta-Analysis.&amp;aulast=Poorsattar-Bejeh+Mir&amp;pid=%3Cauthor%3EPoorsattar-Bejeh+Mir+K%3C%2Fauthor%3E%3CAN%3E26331141%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 16
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Children and adolescents are among the most vulnerable groups affected by natural and man-made disaster. To better understand research and practice concerning mental health and psychosocial support efforts in humanitarian settings, the authors conducted a comprehensive review of all intervention programmes within the past decade that universally targeted children and adolescents who were exposed to a natural and/or man-made disaster. 

**METHODS: **
We searched PubMed, PsychINFO, Cochrane Library and CINAHL for mental health and psychosocial interventions (MHPSS) involving children and adolescents. A total of 11 studies, 4 from natural disasters and 7 from conflict-affected areas met the inclusion criteria. Effect sizes were calculated using a random effects model for studies in post-natural disaster and war/terrorist-affected settings separately. 

**RESULTS:**
The weighted mean effect sizes for interventions in both settings were statistically significant: -0.308, 95% CI=-0.54- -0.07, z=-2.58, p=0.010 after a natural disaster, and -0.514, 95% CI=-0.80 to -0.23, z=-3.57, p&lt;0.001 in conflict areas. This indicates that MHPSS interventions in both disaster settings resulted in a reduction in PTSD symptoms compared to the control. 

**CONCLUSIONS: **
This review suggests that school-based, universal programmes that are conducted by teachers or local paraprofessionals are effective in reducing PTSD symptoms in children and adolescents. The few studies meeting the inclusion criteria of this study demonstrate the need for further expansion of statistical methods and study designs to test for the effects of interventions in challenging humanitarian settings.
AD  - Fu, Christine. a World Vision , Washington , DC , USA. Underwood, Carol. b Johns Hopkins Bloomberg School of Public Health , Baltimore , Maryland , USA.
AN  - 26890398
AU  - Fu,
AU  - C.
AU  - Underwood,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2989/17280583.2015.1117978
DP  - Ovid Technologies
J2  - J
KW  - Adolescent
KW  - Child
KW  - *Disasters
KW  - Humans
KW  - *School Health Services
KW  - Stress Disorders, Post-Traumatic/pc [Prevention &amp; Control]
KW  - *Survivors/px [Psychology]
L1  - internal-pdf://3390367349/Fu.pdf
LA  - English
M3  - Review
N1  - Fu, Christine Underwood, Carol
PY  - 2015
SP  - 161-71
T2  - Journal of Child and Adolescent Mental Health
TI  - A meta-review of school-based disaster interventions for child and adolescent survivors
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26890398http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26890398&amp;id=doi:10.2989%2F17280583.2015.1117978&amp;issn=1728-0583&amp;isbn=&amp;volume=27&amp;issue=3&amp;spage=161&amp;pages=161-71&amp;date=2015&amp;title=Journal+of+Child+%26+Adolescent+Mental+Health&amp;atitle=A+meta-review+of+school-based+disaster+interventions+for+child+and+adolescent+survivors.&amp;aulast=Fu&amp;pid=%3Cauthor%3EFu+C%3C%2Fauthor%3E%3CAN%3E26890398%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 27
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Alcohol-impaired driving persists as a major cause of traffic fatalities and injuries among young drivers. This meta-analysis examined whether brief alcohol interventions were effective in reducing driving after drinking among adolescents and young adults. 

**METHOD: **
Our systematic search identified 12 experimental/quasi-experimental evaluations (16 intervention groups) that measured driving while intoxicated and related consequences and provided data for effect size calculation (N = 5,664; M age =17 years; 57% male). The studies were published between 1991 and 2011. Three-level random-effects meta-analyses using a structural equation modeling approach were used to summarize the effects of the interventions. 

**RESULTS:**
Compared with controls, participants in brief alcohol interventions reported reduced drinking and driving and related consequences (g = 0.15, 95% CI [0.08, 0.21]). Supplemental analyses indicated that reductions in driving while intoxicated were positively associated with the reduced post-intervention heavy use of alcohol. These findings were not attenuated by study design or implementation factors. 

**CONCLUSIONS:** 
Brief alcohol interventions under 5 hours of contact may constitute a promising preventive approach targeting drinking and driving among adolescents and young adults. Reducing heavy episodic alcohol consumption appeared to be a major factor in reducing drunk-driving instances. Interpretation of the findings must be made with caution, however, given the possibility of publication bias and the small observed effect size. Future research should focus on the exact mechanisms of behavior change leading to beneficial outcomes of brief alcohol interventions and the potential effectiveness of combined brief interventions and other preventive approaches.
AD  - Steinka-Fry, Katarzyna T. Peabody Research Institute, Vanderbilt University, USA. Tanner-Smith, Emily E. Peabody Research Institute, Vanderbilt University, USA ; Department of Human and Organizational Development, Vanderbilt University, USA. Hennessy, Emily A. Department of Human and Organizational Development, Vanderbilt University, USA.
AN  - 26221619
AU  - Steinka-Fry,
AU  - K.
AU  - T.
AU  - Tanner-Smith,
AU  - E.
AU  - E.
AU  - Hennessy,
AU  - E.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.13188/2330-2178.1000016
DP  - Ovid Technologies
J2  - J Addict Prev
L1  - internal-pdf://0660392057/Steinka-Fry.pdf
LA  - English
N1  - Steinka-Fry, Katarzyna T Tanner-Smith, Emily E Hennessy, Emily A Using Smart Source Parsing 11
PY  - 2015
T2  - J Addict Prev
TI  - Effects of Brief Alcohol Interventions on Drinking and Driving among Youth: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medp&amp;AN=26221619http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26221619&amp;id=doi:&amp;issn=&amp;isbn=&amp;volume=3&amp;issue=1&amp;spage=&amp;pages=&amp;date=2015&amp;title=%3D%3D%3D&amp;atitle=Effects+of+Brief+Alcohol+Interventions+on+Drinking+and+Driving+among+Youth%3A+A+Systematic+Review+and+Meta-analysis.&amp;aulast=Steinka-Fry&amp;pid=%3Cauthor%3ESteinka-Fry+KT%3C%2Fauthor%3E%3CAN%3E26221619%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 3
ER  -
TY  - JOUR
AB  - This evidence base update examines the level of empirical support for interventions for children with autism spectrum disorder (ASD) younger than 5 years old. It focuses on research published since a previous review in this journal (Rogers &amp; Vismara, 2008 ). 

We identified psychological or behavioral interventions that had been manualized and evaluated in either (a) experimental or quasi-experimental group studies or (b) systematic reviews of single-subject studies. We extracted data from all studies that met these criteria and were published after the previous review. Interventions were categorized across two dimensions. 

First, primary theoretical principles included applied behavior analysis (ABA), developmental social-pragmatic (DSP), or both. Second, practice elements included scope (comprehensive or focused), modality (individual intervention with the child, parent training, or classrooms), and intervention targets (e.g., spoken language or alternative and augmentative communication). 

We classified two interventions as well-established (individual, comprehensive ABA and teacher-implemented, focused ABA + DSP), 3 as probably efficacious (individual, focused ABA for augmentative and alternative communication; individual, focused ABA + DSP; and focused DSP parent training), and 5 as possibly efficacious (individual, comprehensive ABA + DSP; comprehensive ABA classrooms; focused ABA for spoken communication; focused ABA parent training; and teacher-implemented, focused DSP). The evidence base for ASD interventions has grown substantially since 2008. 

An increasing number of interventions have some empirical support; others are emerging as potentially efficacious. Priorities for future research include improving outcome measures, developing interventions for understudied ASD symptoms (e.g., repetitive behaviors), pinpointing mechanisms of action in interventions, and adapting interventions for implementation with fidelity by community providers.
AD  - Smith, Tristram. a Department of Pediatrics , University of Rochester Medical Center. Iadarola, Suzannah. a Department of Pediatrics , University of Rochester Medical Center.
AN  - 26430947
AU  - Smith,
AU  - T.
AU  - Iadarola,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15374416.2015.1077448
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
KW  - *Autism Spectrum Disorder/th [Therapy]
KW  - Behavior Therapy/mt [Methods]
KW  - Child
KW  - Child, Preschool
KW  - Communication
KW  - *Communication Disorders/rh [Rehabilitation]
KW  - Evidence-Based Practice
KW  - Humans
KW  - Parents
KW  - *Social Behavior
KW  - *Speech Therapy/mt [Methods]
KW  - Treatment Outcome
L1  - internal-pdf://2102247765/Evidence Base Update for Autism Spectrum Disor.pdf
LA  - English
M3  - Review
N1  - Smith, Tristram Iadarola, Suzannah
PY  - 2015
SP  - 897-922
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Evidence Base Update for Autism Spectrum Disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26430947http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26430947&amp;id=doi:10.1080%2F15374416.2015.1077448&amp;issn=1537-4416&amp;isbn=&amp;volume=44&amp;issue=6&amp;spage=897&amp;pages=897-922&amp;date=2015&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Evidence+Base+Update+for+Autism+Spectrum+Disorder.&amp;aulast=Smith&amp;pid=%3Cauthor%3ESmith+T%3C%2Fauthor%3E%3CAN%3E26430947%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 44
ER  -
TY  - JOUR
AB  - **Bakgrunn** 
Helsedirektoratet reviderer Nasjonale retningslinjer for behandling av spiseforstyrrelse. Spiseforstyrrelse er den psykiske lidelsen som har høyest dødelighet. Gravide med spiseforstyrrelse er en sårbar gruppe, og i de alvorligere tilfellene kan lidelsene påvirke både mor og barn. Det foreligger begrenset kunnskap om behandling av spiseforstyrrelse hos gravide. Folkehelseinstituttet oppgir at forekomst av spiseforstyrrelser blant kvinner i aldersgruppen 15-44 i Norge er: 0,3 prosent med anoreksi, 2 prosent med bulimi og 3 prosent med overspisningslidelse. Funn fra observasjonsstudier kan tyde på at spiseforstyrrelse har innvirkning på fødselsutfall. Det er påvist sammenheng mellom spiseforstyrrelser og økt forekomst av spontanaborter, diabetes hos mor og prematur fødsel. Det er også vist en mulig sammenheng mellom anoreksi og intrauterin vekstretardasjon. Vi har besvart følgende spørsmål i form av en systematisk oversikt: For gravide med spiseforstyrrelse, hva er effekten av behandlingstiltak og oppfølgingstiltak på vektutvikling hos mor og barn? Hvilken behandling og oppfølging gir best symptomlindring hos gravide med spiseforstyrrelse på &bull; bulimiske symptomer &bull; ernæringstilstand &bull; depressive symptomer? 

**Metode** 
Vi søkte først etter systematiske oversikter som var publisert de seneste fem år. Vi søkte i følgende databaser: Cochrane Database of Systematic Reviews (CDSR), Database of Abstracts of Reviews of Effects (DARE), Health Technology Assessment Database (HTA), MEDLINE, EMBASE, PsycINFO og Cinahl. Vi fant ingen systematiske oversikter med effektstudier. Vi søkte deretter etter effektstudier i følgende databaser: MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), PsycINFO og Cinahl. I tillegg til databasesøk gjennomgikk vi referanselistene på innhentede oversiktsartikler for å finne effektstudier. Søk etter studier ble avsluttet i februar 2015. For å oppfylle våre inklusjonskriterier skulle studiene enten være systematiske oversikter av høy kvalitet eller enkeltstudier med et prospektivt design hvor det også var en kontrollgruppe. Studiene skulle være med gravide som hadde en spiseforstyrrelse (anoreksi, bulimi, overspisingslidelse eller uspesifisert spiseforstyrrelse). De gravide skulle tilbys en eller annen form for strukturert behandlings- og oppfølgingsopplegg (som psykologisk samtale, medisinskfaglig oppfølging) med søkelys på tilfredsstillende vektutvikling hos både mor og barn, samt symptomlette av spiseforstyrrelse og depresjon hos mor. Kontrollgruppen skulle få vanlig oppfølging i henhold til vanlig svangerskapsomsorg eller annen type behandling. To personer vurderte uavhengig av hverandre identifiserte titler og sammendrag mot inklusjonskriteriene. Utvalgte referanser ble innhentet og deretter vurdert uavhengig av hverandre i fulltekst. 
Resultat Litteratursøket endte med 3552 referanser som ble vurdert ut fra titler og sammendrag. Atten referanser ble vurdert i fulltekst. Vi fant ingen studier, verken systematiske oversikter eller effektstudier, som tilfredsstilte de på forhånd fastsatte inklusjonskriteriene. 

**Diskusjon** 
Dersom gravide med spiseforstyrrelse skal tilbys annen behandling enn ikke-gravide med spiseforstyrrelse, er det nødvendig at behandling for gravide blir undersøkt i effektstudier. Før slik dokumentasjon foreligger bør gravide med spiseforstyrrelse følges opp på samme måte som ikke-gravide med spiseforstyrrelse. Vi fant noen få studier som hadde vurdert behandling av kvinner med bulimi som hadde født. Ettersom disse kvinnene ikke var gravide, ble ikke studiene inkludert i vår oversikt. Dessuten gav ingen av studiene pålitelig informasjon om effekter av behandlingene som ble tilbudt (kognitiv terapi, internettbasert gruppeterapi, videofeedback i måltider med små barn). Å kartlegge gravide med spiseforstyrrelse uten å tilby behandling er etisk problematisk. Det er behov for forskning som genererer kunnskap om effekter av tiltak for gravide med spisefortyrrelser. 

**Konklusjon** 
Vi fant ingen studier der effekter av behandlingstiltak for gravide med spiseforstyrrelse er evaluert. Spiseforstyrrelser kan være alvorlige tilstander, og gravide bør tilbys behandling under graviditet. Kunnskap om forekomst og prognose er ikke tilstrekkelig. Behandlingstiltak som er vist effektive for en del personer med spiseforstyrrelse (som gruppeterapi, familieterapi, kognitiv atferdsterapi, innleggelse) kan vurderes til gravide med spiseforstyrrelse.
AU  - Reinar,
AU  - L.
AU  - M.
AU  - Straumann,
AU  - G.
AU  - H.
AU  - Tinderholt
AU  - Myrhaug,
AU  - H.
AU  - Vist,
AU  - G.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/rapport_2015_14_gravide_spiseforstyrrelser.pdf
PY  - 2015
T2  - Folkehelseinstituttet
TI  - Ingen effektstudier om behandling av gravide med spiseforstyrrelse
ER  -
TY  - JOUR
AB  - Previous meta-analyses of psychotherapies for child and adolescent depression were limited because of the small number of trials with direct comparisons between two treatments.

A network meta-analysis, a novel approach that integrates direct and indirect evidence from randomized controlled studies, was undertaken to investigate the comparative efficacy and acceptability of psychotherapies for depression in children and adolescents. Systematic searches resulted in 52 studies (total N=3805) of nine psychotherapies and four control conditions. 

We assessed the efficacy at post-treatment and at follow-up, as well as the acceptability (all-cause discontinuation) of psychotherapies and control conditions. At post-treatment, only interpersonal therapy (IPT) and cognitive-behavioral therapy (CBT) were significantly more effective than most control conditions (standardized mean differences, SMDs ranged from -0.47 to -0.96). Also, IPT and CBT were more beneficial than play therapy. 

Only psychodynamic therapy and play therapy were not significantly superior to waitlist. At follow-up, IPT and CBT were significantly more effective than most control conditions (SMDs ranged from -0.26 to -1.05), although only IPT retained this superiority at both short-term and long-term follow-up. In addition, IPT and CBT were more beneficial than problem-solving therapy. Waitlist was significantly inferior to other control conditions. With regard to acceptability, IPT and problem-solving therapy had significantly fewer all-cause discontinuations than cognitive therapy and CBT (ORs ranged from 0.06 to 0.33). 

These data suggest that IPT and CBT should be considered as the best available psychotherapies for depression in children and adolescents. However, several alternative psychotherapies are understudied in this age group. Waitlist may inflate the effect of psychotherapies, so that psychological placebo or treatment-as-usual may be preferable as a control condition in psychotherapy trials. 

Copyright &copy; 2015 World Psychiatric Association.
AD  - Zhou, Xinyu. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Hetrick, Sarah E. Orygen National Centre of Excellence in Youth Mental Health, University of Melbourne, Melbourne, Australia. Cuijpers, Pim. Department of Clinical Psychology, VU University Amsterdam, Amsterdam, The Netherlands. Qin, Bin. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Barth, Jurgen. Institute of Complementary and Integrative Medicine, University Hospital and University of Zurich, Zurich, Switzerland. Whittington, Craig J. Research Department of Clinical, Educational and Health Psychology, University College London, London, UK. Cohen, David. Department of Child and Adolescent Psychiatry, Hopital Pitie-Salpetriere, Institut des Systemes Intelligents et Robotiques, Universite Pierre et Marie Curie, Paris, France. Del Giovane, Cinzia. Department of Diagnostic, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Modena, Italy. Liu, Yiyun. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Michael, Kurt D. Department of Psychology, Appalachian State University, Boone, NC, USA. Zhang, Yuqing. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Weisz, John R. Department of Psychology, Harvard University, Cambridge, MA, USA. Xie, Peng. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
AN  - 26043339
AU  - Zhou,
AU  - X.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Cuijpers,
AU  - P.
AU  - Qin,
AU  - B.
AU  - Barth,
AU  - J.
AU  - Whittington,
AU  - C.
AU  - J.
AU  - Cohen,
AU  - D.
AU  - Del
AU  - Giovane,
AU  - C.
AU  - Liu,
AU  - Y.
AU  - Michael,
AU  - K.
AU  - D.
AU  - Zhang,
AU  - Y.
AU  - Weisz,
AU  - J.
AU  - R.
AU  - Xie,
AU  - P.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/wps.20217
DP  - Ovid Technologies
J2  - World Psychiatry
L1  - internal-pdf://3260743090/Zhou-2015-Comparative efficacy and acceptabili.pdf
LA  - English
N1  - Zhou, Xinyu Hetrick, Sarah E Cuijpers, Pim Qin, Bin Barth, Jurgen Whittington, Craig J Cohen, David Del Giovane, Cinzia Liu, Yiyun Michael, Kurt D Zhang, Yuqing Weisz, John R Xie, Peng
PY  - 2015
SP  - 207-22
T2  - World Psychiatry
TI  - Comparative efficacy and acceptability of psychotherapies for depression in children and adolescents: A systematic review and network meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26043339http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26043339&amp;id=doi:10.1002%2Fwps.20217&amp;issn=1723-8617&amp;isbn=&amp;volume=14&amp;issue=2&amp;spage=207&amp;pages=207-22&amp;date=2015&amp;title=World+Psychiatry&amp;atitle=Comparative+efficacy+and+acceptability+of+psychotherapies+for+depression+in+children+and+adolescents%3A+A+systematic+review+and+network+meta-analysis.&amp;aulast=Zhou&amp;pid=%3Cauthor%3EZhou+X%3C%2Fauthor%3E%3CAN%3E26043339%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471978/pdf/wps0014-0207.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Students with autism spectrum disorders (ASD) often exhibit rigidity, which can lead to difficulties with transitions. 

Such difficulties can explain why students with ASD are placed in more restrictive educational environments. This review offers a quantitative synthesis of effects of interventions aimed to improve transitions of students with ASD and provides a descriptive overview of the quality of the included studies. 

Analyses focused on the main component of the intervention, topography of challenging behavior, and the type of transition expected of students with ASD. 

Activity schedules were most prominently used and most successful to ease transition difficulties. Strategies that align with preferences of students with ASD also successfully improved transitions. Practical implications and suggestions for future research are provided.
AD  - [Lequia, Jenna; Wilkerson, Kimber L.; Kim, Sunyoung; Lyons, Gregory L.] Univ Wisconsin, Madison, WI 53706 USA. Lequia, J (reprint author), Univ Wisconsin, 1000 Bascom Mall,435 Educ Bldg, Madison, WI 53706 USA. lequia@wisc.edu
AN  - WOS:000355766000003
AU  - Lequia,
AU  - J.
AU  - Wilkerson,
AU  - K.
AU  - L.
AU  - Kim,
AU  - S.
AU  - Lyons,
AU  - G.
AU  - L.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1098300714548799
J2  - J. Posit. Behav. Interv.
KW  - challenging behavior(s)
KW  - intervention(s)
KW  - single-case designs
KW  - data
KW  - analysis
KW  - studies
KW  - special education
KW  - single-case research
KW  - challenging behavior
KW  - activity schedules
KW  - young-children
KW  - developmental-disabilities
KW  - self-injury
KW  - effect size
KW  - individuals
KW  - reliability
KW  - classroom
KW  - Psychology
KW  - Education &amp; Educational Research
L1  - internal-pdf://1594832881/Journal of Positive Behavior Interventions-201.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: CJ8PP Times Cited: 0 Cited Reference Count: 45 Lequia, Jenna Wilkerson, Kimber L. Kim, Sunyoung Lyons, Gregory L. 0 6 13 Sage publications inc Thousand oaks 1538-4772
PY  - 2015
SP  - 146-158
T2  - Journal of Positive Behavior Interventions
TI  - Improving Transition Behaviors in Students With Autism Spectrum Disorders: A Comprehensive Evaluation of Interventions in Educational Settings
UR  - &lt;Go to ISI&gt;://WOS:000355766000003
VL  - 17
ER  -
TY  - JOUR
AB  - **Background:** 
Following traumatic brain injury (TBI) there is an increased prevalence of depression compared to the general population. It is unknown whether non-pharmacological interventions for depression are effective for people with TBI.

**Objectives:** 
To investigate the effectiveness of&nbsp;non-pharmacological interventions for depression in adults and children with TBI at reducing the diagnosis and severity of symptoms of depression.

**Search methods:** 
We ran the most recent search on 11 February 2015. We searched the Cochrane Injuries Group Specialised Register, The Cochrane Library, MEDLINE (OvidSP), Embase (OvidSP), three other databases and clinical trials registers. Relevant conference proceedings and journals were handsearched, as were the reference lists of identified studies.

**Selection criteria:** 
Randomised controlled trials (RCTs) of non-pharmacological interventions for depression in adults and children who had a TBI.

**Data collection and analysis:**
Two authors independently selected trials from the search results, then assessed risk of bias and extracted data from the included trials. The authors contacted trial investigators to obtain missing information. We rated the overall quality of the evidence of the primary outcomes using the GRADE approach.

**Main results:**
Six studies met the inclusion criteria, with a total of 334 adult participants. We identified no studies that included children as participants. All studies were affected by high risk of bias due to a lack of blinding of participants and personnel; five studies were affected by high risk of bias for lack of blinding of outcome assessors. There was high or unclear risk of biases affecting some studies across all the Cochrane risk of bias measures.Three studies compared a psychological intervention (either cognitive behaviour therapy or mindfulness-based cognitive therapy) with a control intervention. Data regarding depression symptom outcome measures were combined in a meta-analysis, but did not find an effect in favour of treatment (SMD -0.14; 95% CI -0.47 to 0.19; Z = 0.83; P = 0.41). The other comparisons comprised of single studies of depression symptoms and compared; cognitive behaviour therapy versus supportive psychotherapy (SMD -0.09; 95% CI -0.65 to 0.48; Z = 0.30; P = 0.77); repetitive transcranial magnetic stimulation plus tricyclic antidepressant (rTMS + TCA) versus tricyclic antidepressant alone (SMD -0.84; 95% CI -1.36 to -0.32; Z = 3;19, P = 0.001); and a supervised exercise program versus exercise as usual (SMD -0.43; 95% CI -0.88 to 0.03; Z = 1.84; P = 0.07). There was very-low quality evidence, small effect sizes and wide variability of results, suggesting that no comparisons showed a reliable effect for any intervention.Only one study mentioned minor, transient adverse events from repetitive transcranial magnetic stimulation.

**Authors&#039; conclusions:** 
The review did not find compelling evidence in favour of any intervention. Future studies should focus on participants with a diagnosed TBI and include only participants who have a diagnosis of depression, or who record scores above a clinical cutoff on a depression measure. There is a need for additional RCTs that include a comparison between an intervention and a control that replicates the effect of the attention given to participants during an active treatment.
AN  - CD009871
AU  - Gertler,
AU  - P.
AU  - Tate,
AU  - R.
AU  - L.
AU  - Cameron,
AU  - I.
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009871.pub2
KW  - Antidepressive Agents [therapeutic use]
KW  - Brain Injuries [psychology]
KW  - Cognitive Therapy [methods]
KW  - Depression [etiology] [therapy]
KW  - Exercise [psychology]
KW  - Mindfulness
KW  - Randomized Controlled Trials as Topic
KW  - Suicide [prevention &amp; control]
KW  - Transcranial Magnetic Stimulation [methods]
KW  - Adult[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Inj
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Non-pharmacological interventions for depression in adults and children with traumatic brain injury
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009871.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009871.pub2/asset/CD009871.pdf?v=1&amp;t=iw7kblrn&amp;s=282801842ae6c3108d012568bf60afc889e43606
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
This systematic review evaluated the effectiveness of distraction for reducing infant distress during vaccinations in young children aged 0 to 3 years. 

**DESIGN/METHODS: **
Database searches identified relevant randomized and quasi-randomized controlled trials. Three separate clinical questions related to variants of the psychological strategy of distraction (directed video; directed toy; nondirected toy) were pursued. Distress was identified as the critical outcome to assess the benefits of distraction and extracted from relevant trials. Distress was analyzed by phase of procedure (distress preprocedure; distress acute; distress recovery; idiosyncratic phases based on some or all of the 3 aforementioned phases). 

**RESULTS: **
Ten studies were included in the review. Significant results are presented herein. For directed video distraction, moderate quality evidence suggested that distress was lowered in the treatment group standardized mean difference (SMD -0.68 lower [95% confidence interval (CI), -1.04 to -0.32]) for the acute+recovery phase as well as the preprocedure phase (SMD -0.49 lower [95% CI, -7.6 to -0.22]). For directed toy distraction, the analysis of low-quality evidence for a combined preprocedure+acute+recovery phase of distress (analysis n=81), suggested that distress was lowered in the treatment group (SMD -0.47 lower [95% CI, -0.91 to -0.02]). An effect for nondirected toy distraction was also seen, analyzing very-low-quality evidence, for the acute distress phase (n=290; SMD -0.93 lower [95% CI, -1.86 to 0.00]). 

**CONCLUSION: **
Generally low-quality to very-low-quality evidence suggests that there may be an effect of directed (toy and video) and nondirected toy distraction for children aged 0 to 3 years, for certain phases of the vaccination.
AD  - Pillai Riddell, Rebecca. *Department of Psychology, York University +Department of Psychiatry, The Hospital for Sick Children Child Health and Evaluative Sciences Department of Neonatology ++Department of Psychiatry Leslie Dan Faculty of Pharmacy Faculty of Medicine, University of Toronto ++++Mount Sinai Hospital, Toronto, ON PDepartment of Psychology, University of Guelph, Guelph #Children&#039;s Health Research Institute, Children&#039;s Hospital **Department of Paediatrics, Western University, London, ON ++Department of Pediatrics and Psychology, Centre for Pediatric Pain Research, IWK Health Centre, Dalhousie University, Halifax, NS, Canada PPDepartment of Psychology, University of Calgary, AB, Canada.
AN  - 26201014
AU  - Pillai
AU  - Riddell,
AU  - R.
AU  - Taddio,
AU  - A.
AU  - McMurtry,
AU  - C.
AU  - M.
AU  - Chambers,
AU  - C.
AU  - Shah,
AU  - V.
AU  - Noel,
AU  - M.
AU  - HELPinKIDS
AU  - Team
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/AJP.0000000000000279
DP  - Ovid Technologies
J2  - Clin J Pain
KW  - Child, Preschool
KW  - Databases, Bibliographic/sn [Statistics &amp; Numerical Data]
KW  - Female
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - *Injections/ae [Adverse Effects]
KW  - Male
KW  - *Pain/rh [Rehabilitation]
KW  - *Psychotherapy/mt [Methods]
KW  - *Randomized Controlled Trials as Topic
KW  - *Vaccination/ae [Adverse Effects]
L1  - internal-pdf://2118689238/00002508-201510001-00007.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Pillai Riddell, Rebecca Taddio, Anna McMurtry, C Meghan Chambers, Christine Shah, Vibhuti Noel, Melanie HELPinKIDS Team Ipp M MacDonald N Rogers J Bucci L Mousmanis P Lang E Halperin S Bowles S Halpert C Rieder M Robson K Asmundson GJ Uleryk E Antony M Dubey V Hanrahan A Lockett D Scott J Votta Bleeker E
PY  - 2015
SP  - S64-71
T2  - Clinical Journal of Pain
TI  - Psychological Interventions for Vaccine Injections in Young Children 0 to 3 Years: Systematic Review of Randomized Controlled Trials and Quasi-Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26201014http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26201014&amp;id=doi:10.1097%2FAJP.0000000000000279&amp;issn=0749-8047&amp;isbn=&amp;volume=31&amp;issue=10&amp;spage=S64&amp;pages=S64-71&amp;date=2015&amp;title=Clinical+Journal+of+Pain&amp;atitle=Psychological+Interventions+for+Vaccine+Injections+in+Young+Children+0+to+3+Years%3A+Systematic+Review+of+Randomized+Controlled+Trials+and+Quasi-Randomized+Controlled+Trials.&amp;aulast=Pillai+Riddell&amp;pid=%3Cauthor%3EPillai+Riddell+R%3C%2Fauthor%3E%3CAN%3E26201014%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 31
ER  -
TY  - JOUR
AB  - **Background:*&#039; 
Depression is a debilitating condition affecting more than 350 million people worldwide (WHO 2012) with a limited number of evidence-based treatments. Drug treatments may be inappropriate due to side effects and cost, and not everyone can use talking therapies. There is a need for evidence-based treatments that can be applied across cultures and with people who find it difficult to verbally articulate thoughts and feelings. Dance movement therapy (DMT) is used with people from a range of cultural and intellectual backgrounds, but effectiveness remains unclear.

**Objectives:** 
To examine the effects of DMT for depression with or without standard care, compared to no treatment or standard care alone, psychological therapies, drug treatment, or other physical interventions. Also, to compare the effectiveness of different DMT approaches.

**Search methods:** 
The Cochrane Depression, Anxiety and Neurosis Review Group&#039;s Specialised Register (CCDANCTR-Studies and CCDANCTR-References) and CINAHL were searched (to 2 Oct 2014) together with the World Health Organization&#039;s International Clinical Trials Registry Platform (WHO ICTRP) and ClinicalTrials.gov. The review authors also searched the Allied and Complementary Medicine Database (AMED), the Education Resources Information Center (ERIC) and Dissertation Abstracts (to August 2013), handsearched bibliographies, contacted professional associations, educational programmes and dance therapy experts worldwide.

**Selection criteria:** 
Inclusion criteria were: randomised controlled trials (RCTs) studying outcomes for people of any age with depression as defined by the trialist, with at least one group being DMT. DMT was defined as: participatory dance movement with clear psychotherapeutic intent, facilitated by an individual with a level of training that could be reasonably expected within the country in which the trial was conducted. For example, in the USA this would either be a trainee, or qualified and credentialed by the American Dance Therapy Association (ADTA). In the UK, the therapist would either be in training with, or accredited by, the Association for Dance Movement Psychotherapy (ADMP, UK). Similar professional bodies exist in Europe, but in some countries (e.g. China) where the profession is in development, a lower level of qualification would mirror the situation some decades previously in the USA or UK. Hence, the review authors accepted a relevant professional qualification (e.g. nursing or psychodynamic therapies) plus a clear description of the treatment that would indicate its adherence to published guidelines including Levy 1992, ADMP UK 2015, Meekums 2002, and Karkou 2006.

**Data collection and analysis:** 
Study methodological quality was evaluated and data were extracted independently by the first two review authors using a data extraction form, the third author acting as an arbitrator.Main results: Three studies totalling 147 participants (107 adults and 40 adolescents) met the inclusion criteria. Seventy-four participants took part in DMT treatment, while 73 comprised the control groups. Two studies included male and female adults with depression. One of these studies included outpatient participants; the other study was conducted with inpatients at an urban hospital. The third study reported findings with female adolescents in a middle-school setting. All included studies collected continuous data using two different depression measures: the clinician-completed Hamilton Depression Rating Scale (HAM-D); and the Symptom Checklist-90-R (SCL-90-R) (self-rating scale).Statistical heterogeneity was identified between the three studies. There was no reliable effect of DMT on depression (SMD -0.67 95% CI -1.40 to 0.05; very low quality evidence). A planned subgroup analysis indicated a positive effect in adults, across two studies, 107 participants, but this failed to meet clinical significance (SMD -7.33 95% CI -9.92 to -4.73).One adult study reported drop-out rates, found to be non-significant with an odds ratio of 1.82 [95% CI 0.35 to 9.45]; low quality evidence. One s u y measured social functioning, demonstrating a large positive effect (MD -6.80 95 % CI -11.44 to -2.16; very low quality evidence), but this result was imprecise. One study showed no effect in either direction for quality of life (0.30 95% CI -0.60 to 1.20; low quality evidence) or self esteem (1.70 95% CI -2.36 to 5.76; low quality evidence).

**Authors&#039; conclusions:** 
The low-quality evidence from three small trials with 147 participants does not allow any firm conclusions to be drawn regarding the effectiveness of DMT for depression. Larger trials of high methodological quality are needed to assess DMT for depression, with economic analyses and acceptability measures and for all age groups.
AN  - CD009895
AU  - Meekums,
AU  - B.
AU  - Karkou,
AU  - V.
AU  - Nelson,
AU  - E.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009895.pub2.
KW  - Movement
KW  - Antidepressive Agents [therapeutic use]
KW  - Dance Therapy [methods]
KW  - Depression [therapy]
KW  - Empathy
KW  - Psychotherapy
KW  - Randomized Controlled Trials as Topic
KW  - Sensation
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Depressn
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Dance movement therapy for depression
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009895.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009895.pub2/asset/CD009895.pdf?v=1&amp;t=iw7j7zun&amp;s=f9ea66b70be8e39758f1040f4c163f1fccad04b6
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The purpose of this review is to study the effect of school-based interventions on smoking prevention for girls. 

**METHODS: **
We performed a systematic review of articles published since 1992 on school-based tobacco-control interventions in controlled trials for smoking prevention among children. We searched the databases of PubMed, Embase, Web of Science, The Cochrane Databases, CINAHL, Social Science Abstracts, and PsycInfo. Two reviewers independently assessed trials for inclusion and quality and extracted data. A pooled random-effects estimate was estimated of the overall relative risk. 

**RESULTS: **
Thirty-seven trials were included, of which 16 trials with 24,210 girls were included in the pooled analysis. The overall pooled effect was a relative risk (RR) of 0.96 (95 % confidence interval (CI) 0.86-1.08; I (2)=75 %). One study in which a school-based intervention was combined with a mass media intervention showed more promising results compared to only school-based prevention, and four studies with girl-specific interventions, that could not be included in the pooled analysis, reported statistically significant benefits for attitudes and intentions about smoking and quit rates. 

**CONCLUSIONS: **
There was no evidence that school-based smoking prevention programs have a significant effect on preventing adolescent girls from smoking. Combining school-based programs with mass media interventions, and developing girl-specific interventions, deserve additional study as potentially more effective interventions compared to school-based-only intervention programs. 

Systematic review registration: prospero crd42012002322.
AD  - de Kleijn, Miriam J J. Gender &amp; Women&#039;s Health, Department of Primary and Community Care, Radboud University Medical Center, Postbus 9101, 6500 HB, Nijmegen, The Netherlands. mjjdekleijn@me.com. Farmer, Melissa M. VA HSR&amp;D Center for the Study of Healthcare Innovation, Implementation, and Policy, VA Greater Los Angeles Healthcare System, 16111 Plummer Street, North Hills, CA, 91343, USA. Melissa.Farmer@va.gov. Booth, Marika. RAND Corporation, 1776 Main Street, 90401, Santa Monica, CA, USA. suttorp@rand.org. Motala, Aneesa. RAND Corporation, 1776 Main Street, 90401, Santa Monica, CA, USA. amotala@rand.org. Smith, Alexandria. RAND Corporation, 1776 Main Street, 90401, Santa Monica, CA, USA. asmith@rand.org. Sherman, Scott. Veterans Affairs New York Harbor Healthcare System, 423 East 23rd Street, 10010, New York, NY, USA. Scott.Sherman@nyumc.org. Sherman, Scott. New York University Langone Medical Center, 227 East 30th Room 642, 10016, New York, NY, USA. Scott.Sherman@nyumc.org. Assendelft, Willem J J. Department of Primary and Community Care, Radboud University Medical Center, Postbus 9101, 6500 HB, Nijmegen, The Netherlands. pim.assendelft@radboudumc.nl. Shekelle, Paul. RAND Corporation, 1776 Main Street, 90401, Santa Monica, CA, USA. shekelle@rand.org. Shekelle, Paul. Veterans Affairs Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, 90073, Los Angeles, CA, USA. shekelle@rand.org.
AN  - 26272326
AU  - de
AU  - Kleijn,
AU  - M.
AU  - J.
AU  - Farmer,
AU  - M.
AU  - M.
AU  - Booth,
AU  - M.
AU  - Motala,
AU  - A.
AU  - Smith,
AU  - A.
AU  - Sherman,
AU  - S.
AU  - Assendelft,
AU  - W.
AU  - J.
AU  - Shekelle,
AU  - P.
DA  - Aug 14
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/s13643-015-0082-7
DP  - Ovid Technologies
J2  - Syst
KW  - Adolescent
KW  - *Adolescent Behavior
KW  - Female
KW  - Humans
KW  - *Program Evaluation
KW  - *School Health Services
KW  - *Schools
KW  - *Smoking/pc [Prevention &amp; Control]
L1  - internal-pdf://0023838753/de-2015-Systematic review of school-based inte.pdf
LA  - English
M3  - Research Support, U.S. Gov&#039;t, Non-P.H.S. Review
N1  - de Kleijn, Miriam J J Farmer, Melissa M Booth, Marika Motala, Aneesa Smith, Alexandria Sherman, Scott Assendelft, Willem J J Shekelle, Paul 10.1186/s13643-015-0082-7
PY  - 2015
SP  - 109
T2  - Systematic Reviews
TI  - Systematic review of school-based interventions to prevent smoking for girls
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26272326http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26272326&amp;id=doi:10.1186%2Fs13643-015-0082-7&amp;issn=2046-4053&amp;isbn=&amp;volume=4&amp;issue=&amp;spage=109&amp;pages=109&amp;date=2015&amp;title=Systematic+Reviews&amp;atitle=Systematic+review+of+school-based+interventions+to+prevent+smoking+for+girls.&amp;aulast=de+Kleijn&amp;pid=%3Cauthor%3Ede+Kleijn+MJ%3C%2Fauthor%3E%3CAN%3E26272326%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://download.springer.com/static/pdf/110/art%253A10.1186%252Fs13643-015-0082-7.pdf?originUrl=http%3A%2F%2Fsystematicreviewsjournal.biomedcentral.com%2Farticle%2F10.1186%2Fs13643-015-0082-7&amp;token2=exp=1489063403~acl=%2Fstatic%2Fpdf%2F110%2Fart%25253A10.1186%25252Fs13643-015-0082-7.pdf*~hmac=2b936398f47dcb85c164c015314a6a6a118e48c5b5b3b3ff97fa7442f6f21d22
VL  - 4
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Several studies have shown that lisdexamfetamine (LDX) is efficacious in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). 

**OBJECTIVES: **
Aims of this study were to systematically review the efficacy, acceptability, and tolerability of LDX in child and adolescent ADHD. Any randomized controlled trials (RCTs) of LDX versus placebo carried out in children and adolescents with ADHD were included. 

**DATA SOURCES: **
The searches of the SCOPUS, MEDLINE, CINAHL and Cochrane Controlled Trials Register were performed in September 2014. Additional searches in the ClinicalTrials. gov and EU Clinical Trials Register database were conducted.

**STUDY ELIGIBILITY CRITERIA PARTICIPANTS AND INTERVENTIONS: **
This review included all RCTs of LDX versus placebo which were carried out in children and adolescents up to 18 years old. Additionally, the included studies must have reported the final outcomes of: i) severity of ADHD symptoms with standardized scales, ii) rates of improvement, iii) rates of discontinuation. To be more thorough, the languages of such RCTs were not limited. 

**STUDY APPRAISAL AND SYNTHESIS METHODS: **
The abstracts from databases were inspected and the full text versions of relevant trials were examined and extracted for important outcomes. The efficacious measurements included either the pooled mean end-point or changed scores of ADHD rating scales, and the rate of improvement. Acceptability and tolerability were measured by the pooled overall discontinuation rate and the pooled discontinuation rate due to adverse events, respectively. A random effect model technique was utilized to synthesize the mean differences (either standardized mean differences or weighted mean differences) and relative risks (RRs) with 95% confidence intervals (CIs). 

**RESULTS: **
A total of 1,016 children and adolescents with ADHD were included. The dosage of LDX was 30 to 70 mg/day. The pooled mean change scores of LDX-treated group was significantly greater than that of the placebo (weighted mean difference [95% CI] of -15.20 [-19.95, -10.46], I (2)=94%). The pooled improvement rate of the LDX-treated group was also significantly higher than that of the placebo (RR [95% CI] of 0.34 [0.24, 0.47], I (2)=80%). The pooled overall discontinuation rate between the two groups was not significantly different (RR [95% CI] of 0.78 [0.46, 1.31], I (2)=63%). Similarly, the pooled discontinuation rate due to adverse events between the two groups showed no significant difference (RR [95% CI] of 1.99 [0.70, 5.64], I (2)=0%).

**LIMITATIONS: **
The number of included studies was limited (five RCTs). 

**CONCLUSION: **
According to the present review, LDX was effective and well-tolerated in the treatment of child and adolescent ADHD. Unfortunately, the acceptability of LDX was not better than the placebo. Since the number of included studies was limited, the outcome from this review should be carefully interpreted and considered as preliminary. Further studies, therefore, should be conducted to confirm these findings. 

**IMPLICATION OF KEY FINDINGS: **
Lisdexamfetamine is an efficacious stimulant for treating child and adolescent ADHD.
AD  - Maneeton, Benchalak. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Maneeton, Narong. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Likhitsathian, Surinporn. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Suttajit, Sirijit. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Narkpongphun, Assawin. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Srisurapanont, Manit. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Woottiluk, Pakapan. Psychiatric Nursing Division, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand.
AN  - 25897203
AU  - Maneeton,
AU  - B.
AU  - Maneeton,
AU  - N.
AU  - Likhitsathian,
AU  - S.
AU  - Suttajit,
AU  - S.
AU  - Narkpongphun,
AU  - A.
AU  - Srisurapanont,
AU  - M.
AU  - Woottiluk,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2147/DDDT.S79071
DP  - Ovid Technologies
J2  - Drug Des Devel Ther
KW  - Adolescent
KW  - *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy]
KW  - Child
KW  - Drug Tolerance
KW  - Humans
KW  - Lisdexamfetamine Dimesylate/ad [Administration &amp; Dosage]
KW  - Lisdexamfetamine Dimesylate/ae [Adverse Effects]
KW  - *Lisdexamfetamine Dimesylate/tu [Therapeutic Use]
KW  - Randomized Controlled Trials as Topic
KW  - SJT761GEGS (Lisdexamfetamine Dimesylate)
L1  - internal-pdf://0820012862/Maneeton-2015-Comparative efficacy, acceptabil.pdf
LA  - English
M3  - Comparative Study Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Maneeton, Benchalak Maneeton, Narong Likhitsathian, Surinporn Suttajit, Sirijit Narkpongphun, Assawin Srisurapanont, Manit Woottiluk, Pakapan dddt-9-1927
PY  - 2015
SP  - 1927-36
T2  - Drug design, development and therapy
TI  - Comparative efficacy, acceptability, and tolerability of lisdexamfetamine in child and adolescent ADHD: a meta-analysis of randomized, controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25897203http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25897203&amp;id=doi:10.2147%2FDDDT.S79071&amp;issn=1177-8881&amp;isbn=&amp;volume=9&amp;issue=&amp;spage=1927&amp;pages=1927-36&amp;date=2015&amp;title=Drug+design%2C+development+%26+therapy&amp;atitle=Comparative+efficacy%2C+acceptability%2C+and+tolerability+of+lisdexamfetamine+in+child+and+adolescent+ADHD%3A+a+meta-analysis+of+randomized%2C+controlled+trials.&amp;aulast=Maneeton&amp;pid=%3Cauthor%3EManeeton+B%3C%2Fauthor%3E%3CAN%3E25897203%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3E
UR  - https://www.dovepress.com/getfile.php?fileID=24408
VL  - 9
ER  -
TY  - JOUR
AB  - Externalizing disorders are the most common and persistent forms of maladjustment in childhood. 

The aim of this study was to conduct a meta-analysis evaluating the effectiveness of Cognitive Behavioral Therapy (CBT) to reduce externalizing symptoms in two disorders: Attention Deficit Hyperactivity Disorder (ADHD) and Oppositive Defiant Disorder (ODD). The efficacy of CBT to improve social competence and positive parenting and reduce internalizing behaviors, parent stress and maternal depression was also explored. The database PsycInfo, PsycARTICLES, Medline and PubMed were searched to identify relevant studies. 

Twenty-one trials met the inclusion criteria. Results showed that the biggest improvement, after CBT, was in ODD symptoms (-0.879) followed by parental stress (-0.607), externalizing symptoms (-0.52), parenting skills (-0.381), social competence (-0.390) and ADHD symptoms (-0.343). CBT was also associated with improved attention (-0.378), aggressive behaviors (-0.284), internalizing symptoms (-0.272) and maternal depressive symptoms (-0.231). 

Overall, CBT is an effective treatment option for externalizing disorders and is also associated with reduced parental distress and maternal depressive symptoms. Multimodal treatments targeting both children and caregivers&#039; symptoms (e.g. maternal depressive symptoms) appear important to produce sustained and generalized benefits. 

Copyright &copy; 2015 Elsevier Ltd. All rights reserved.
AD  - Battagliese, Gemma. Scuola di Psicoterapia Cognitiva S.r.l., Viale Castro Pretorio 116, 00185, Roma, Italy; Department of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185, Rome, Italy. Electronic address: gemma.battagliese@uniroma1.it. Caccetta, Maria. Scuola di Psicoterapia Cognitiva S.r.l., Viale Castro Pretorio 116, 00185, Roma, Italy. Luppino, Olga Ines. Scuola di Psicoterapia Cognitiva S.r.l., Viale Castro Pretorio 116, 00185, Roma, Italy. Baglioni, Chiara. Scuola di Psicoterapia Cognitiva S.r.l., Viale Castro Pretorio 116, 00185, Roma, Italy; Department of Psychiatry and Psychotherapy, Freiburg University Medical Center, Hauptstrasse 5, D-79104, Freiburg, Germany. Cardi, Valentina. Scuola di Psicoterapia Cognitiva S.r.l., Viale Castro Pretorio 116, 00185, Roma, Italy; Section of Eating Disorders, Psychological Medicine, Institute of Psychiatry, King&#039;s College London, London, UK. Mancini, Francesco. Scuola di Psicoterapia Cognitiva S.r.l., Viale Castro Pretorio 116, 00185, Roma, Italy. Buonanno, Carlo. Scuola di Psicoterapia Cognitiva S.r.l., Viale Castro Pretorio 116, 00185, Roma, Italy.
AN  - 26575979
AU  - Battagliese,
AU  - G.
AU  - Caccetta,
AU  - M.
AU  - Luppino,
AU  - O.
AU  - I.
AU  - Baglioni,
AU  - C.
AU  - Cardi,
AU  - V.
AU  - Mancini,
AU  - F.
AU  - Buonanno,
AU  - C.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.brat.2015.10.008
DP  - Ovid Technologies
J2  - Behav Res Ther
KW  - Adolescent
KW  - Adult
KW  - Aggression/px [Psychology]
KW  - Attention Deficit Disorder with Hyperactivity/px [Psychology]
KW  - *Attention Deficit Disorder with Hyperactivity/th [Therapy]
KW  - Attention Deficit and Disruptive Behavior Disorders/px [Psychology]
KW  - *Attention Deficit and Disruptive Behavior Disorders/th [Therapy]
KW  - Caregivers
KW  - Child
KW  - *Cognitive Therapy/mt [Methods]
KW  - Education, Nonprofessional
KW  - Female
KW  - Humans
KW  - Longitudinal Studies
KW  - Male
KW  - Middle Aged
KW  - Parenting
KW  - Parents
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
L1  - internal-pdf://3895102528/Battagliese-2015-Cognitive-behavioral therapy.pdf
LA  - English
M3  - Meta-Analysis
N1  - Battagliese, Gemma Caccetta, Maria Luppino, Olga Ines Baglioni, Chiara Cardi, Valentina Mancini, Francesco Buonanno, Carlo S0005-7967(15)30048-6
PY  - 2015
SP  - 60-71
T2  - Behaviour Research &amp; Therapy
TI  - Cognitive-behavioral therapy for externalizing disorders: A meta-analysis of treatment effectiveness
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26575979http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26575979&amp;id=doi:10.1016%2Fj.brat.2015.10.008&amp;issn=0005-7967&amp;isbn=&amp;volume=75&amp;issue=&amp;spage=60&amp;pages=60-71&amp;date=2015&amp;title=Behaviour+Research+%26+Therapy&amp;atitle=Cognitive-behavioral+therapy+for+externalizing+disorders%3A+A+meta-analysis+of+treatment+effectiveness.&amp;aulast=Battagliese&amp;pid=%3Cauthor%3EBattagliese+G%3C%2Fauthor%3E%3CAN%3E26575979%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0005796715300486/1-s2.0-S0005796715300486-main.pdf?_tid=49d57afc-04c2-11e7-a03b-00000aacb362&amp;acdnat=1489061996_6c4a6f88727cbbc7fff438876f4e57e0
VL  - 75
ER  -
TY  - JOUR
AB  - The importance of the family as a unit in the aftermath of trauma necessitates the use of family interventions among immigrants and refugees. While abundant clinical material suggests that family-based trauma interventions are applicable across cultures, very little is known about the extent to which family treatment modalities are effective for immigrants and refugees. 

We conducted a systematic review of intervention studies that have been designed or modified specifically for traumatized immigrant and refugee families. The terms &quot;trauma,&quot; &quot;family,&quot; and &quot;immigrants/refugees/culture&quot; were used along with different terms for &quot;intervention.&quot; 

Studies with no research methodology were excluded. Only 6 experimental studies met our inclusion criteria; 4 of them describe school-based interventions and 2 present multifamily support groups. The shortage of research in this area does not allow clear conclusions about the effectiveness of family interventions for traumatized immigrants or refugees. 

The complexity of employing methodologically rigorous research in small communities is discussed. Future trials should go beyond the individualistic approach and focus on posttraumatic stress disorder to address family-level processes, such as family relationship, communication, and resilience. 

Copyright &copy; The Author(s) 2015.
AD  - Slobodin, Ortal. i-psy, the Netherlands ortal_saroff@yahoo.com. de Jong, Joop T V M. University of AmsterdamBoston University.
AN  - 26047828
AU  - Slobodin,
AU  - O,
AU  - de,
AU  - Jong
AU  - J,
AU  - T.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1363461515588855
DP  - Ovid Technologies
J2  - Transcult Psychiatry
KW  - *Emigrants and Immigrants/px [Psychology]
KW  - *Family Therapy
KW  - Humans
KW  - *Psychological Trauma/th [Therapy]
KW  - *Refugees/px [Psychology]
L1  - internal-pdf://1368440407/Slobodin-2015-Family interventions in traumati.pdf
LA  - English
M3  - Review
N1  - Slobodin, Ortal de Jong, Joop T V M 1363461515588855
PY  - 2015
SP  - 723-42
T2  - Transcultural Psychiatry
TI  - Family interventions in traumatized immigrants and refugees: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26047828http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26047828&amp;id=doi:10.1177%2F1363461515588855&amp;issn=1363-4615&amp;isbn=&amp;volume=52&amp;issue=6&amp;spage=723&amp;pages=723-42&amp;date=2015&amp;title=Transcultural+Psychiatry&amp;atitle=Family+interventions+in+traumatized+immigrants+and+refugees%3A+A+systematic+review.&amp;aulast=Slobodin&amp;pid=%3Cauthor%3ESlobodin+O%3C%2Fauthor%3E%3CAN%3E26047828%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 52
ER  -
TY  - JOUR
AB  - **PURPOSE: **
To assess the effect of multidisciplinary intervention (MI) programs for overweight and obese children on quality of life (QoL). 

**METHODS: **
Medline, EMBASE, Web of Science and Cochrane databases were searched for relevant studies without date restrictions up to July 2014. Included were randomized controlled trials and controlled clinical trials evaluating an MI aimed to reduce weight in overweight children and reporting QoL. The risk of bias of the included studies was assessed using the Cochrane guidelines. Data were pooled for short- (up to 6 months) and long-term (12-18 months) effects using a random effects model. 

**RESULTS: **
In total, 11 studies were included, studying a total of 997 children aged 3-18 years. No significant differences were found between MI and control interventions on short-term QoL outcomes [mean difference (MD) 1.73, 95 % confidence interval (CI) -0.26 to 3.73 on a 0-100 scale]. Long-term results showed a nonsignificant trend toward a higher QoL in children following an MI program compared with control interventions (MD 4.40 95 % CI -0.12 to 8.92). 

**CONCLUSION: **
There is insufficient evidence that MI programs, aimed to reduce weight in overweight and obese children, improve QoL.
AD  - Ligthart, Kelly A M. Department of General Practice, Erasmus MC, University Medical Center, Room Na-1923, PO Box 2040, 3000 CA, Rotterdam, The Netherlands, k.ligthart@erasmusmc.nl.
AN  - 25477229
AU  - Ligthart,
AU  - K.
AU  - A.
AU  - Paulis,
AU  - W.
AU  - D.
AU  - Djasmo,
AU  - D.
AU  - Koes,
AU  - B.
AU  - W.
AU  - van,
AU  - Middelkoop,
AU  - M.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
J2  - Qual Life Res
KW  - Adolescent
KW  - Child
KW  - Child, Preschool
KW  - Female
KW  - Humans
KW  - *Interdisciplinary Communication
KW  - Male
KW  - *Obesity/co [Complications]
KW  - *Overweight/co [Complications]
KW  - *Quality of Life
KW  - Risk Factors
L1  - internal-pdf://4086316587/Ligthart-2015-Effect of multidisciplinary inte.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Ligthart, Kelly A M Paulis, Winifred D Djasmo, Dewi Koes, Bart W van Middelkoop, Marienke
PY  - 2015
SP  - 1635-43
T2  - Quality of Life Research
TI  - Effect of multidisciplinary interventions on quality of life in obese children: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25477229http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25477229&amp;id=doi:10.1007%2Fs11136-014-0881-7&amp;issn=0962-9343&amp;isbn=&amp;volume=24&amp;issue=7&amp;spage=1635&amp;pages=1635-43&amp;date=2015&amp;title=Quality+of+Life+Research&amp;atitle=Effect+of+multidisciplinary+interventions+on+quality+of+life+in+obese+children%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Ligthart&amp;pid=%3Cauthor%3ELigthart+KA%3C%2Fauthor%3E%3CAN%3E25477229%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://link.springer.com/article/10.1007%2Fs11136-014-0881-7
UR  - http://download.springer.com/static/pdf/851/art%253A10.1007%252Fs11136-014-0881-7.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs11136-014-0881-7&amp;token2=exp=1489074080~acl=%2Fstatic%2Fpdf%2F851%2Fart%25253A10.1007%25252Fs11136-014-0881-7.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs11136-014-0881-7*~hmac=65cd3a7e51ca7ac3f359f1afbd31cdafd30ee4deeac275eb10794db792d1d447
VL  - 24
ER  -
TY  - JOUR
AB  - Bakgrunn
Denne artikkelen er en kunnskapsoppsummering om effektene av tiltaket Edinburgh-metoden (EPDS med støttesamtaler) i Norge. Artikkelen er en revisjon av en tidligere beskrivelse av det samme tiltaket i Ungsinn (Reedtz, 2012), men videreutviklet i henhold til Ungsinn sine nye prosedyrer og kriterier. Edinburgh-metoden er et individbasert tiltak for gravide og nybakte mødre. Tiltaket består av to deler; der den første delen er utfylling av screeningsinstrumentet EPDS, etterfulgt av en samtale med helsesøster eller jordmor om utfyllingen. Den andre delen av tiltaket er oppfølgingssamtale/r med helsesøster om mors psykiske helse.

Metode
Denne kunnskapsoppsummeringen bygger på et systematisk litteratursøk i databasene Embase, Medline og Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS og SweMed. To artikler tilfredsstilte kriteriene for inklusjon og ble inkludert i oppsummeringen.

Resultatene
Resultatene omfatter en oppsummering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Tiltaket er beskrevet i faglitteratur der målsetning og målgrupper er tilfredsstillende definert. Edinburgh-metoden har en velbegrunnet teori for noen virkningsmekanismer i tiltaket. Det foreligger to norske studier som har undersøkt tiltakets effekt. Begge studiene benyttet et kvasi-eksperimentelt design med en sammenligningsgruppe og pre-post test målinger. Studiene som er gjennomført har metodiske mangler ut i fra Ungsinns klassifiseringssystem. Det foreligger &eacute;n oppfølgingsstudie. Tiltaket har et mangelfullt system for kvalitetssikring av implementeringskvalitet.

Konklusjon
Basert på Ungsinns kriterier klassifiseres EPDS på evidensnivå 3 &ndash; Tiltak med noe dokumentasjon på effekt.
AU  - Reedtz,
AU  - C.,
AU  - Lauritzen,
AU  - C.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2015
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: Edinburgh-metoden (2. utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/kunnskapsoppsummering-og-klassifisering-av-tiltaket-edinburgh-metoden-epds-med-stottesamtaler/
VL  - 2
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Attention-deficit hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and conduct disorder (CD) are among the most common psychiatric diagnoses in childhood. Aggression and conduct problems are a major source of disability and a risk factor for poor long-term outcomes. 

**METHODS: **
We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) of antipsychotics, lithium, and anticonvulsants for aggression and conduct problems in youth with ADHD, ODD, and CD. Each medication was given an overall quality of evidence rating based on the Grading of Recommendations Assessment, Development and Evaluation approach. 

**RESULTS: **
Eleven RCTs of antipsychotics and 7 RCTs of lithium and anticonvulsants were included. There is moderate-quality evidence that risperidone has a moderate-to-large effect on conduct problems and aggression in youth with subaverage IQ and ODD, CD, or disruptive behaviour disorder not otherwise specified, with and without ADHD, and high-quality evidence that risperidone has a moderate effect on disruptive and aggressive behaviour in youth with average IQ and ODD or CD, with and without ADHD. Evidence supporting the use of haloperidol, thioridazine, quetiapine, and lithium in aggressive youth with CD is of low or very-low quality, and evidence supporting the use of divalproex in aggressive youth with ODD or CD is of low quality. There is very-low-quality evidence that carbamazepine is no different from placebo for the management of aggression in youth with CD. 

**CONCLUSION: **
With the exception of risperidone, the evidence to support the use of antipsychotics and mood stabilizers is of low quality.
AD  - Pringsheim, Tamara. Assistant Professor, Department of Clinical Neurosciences, Psychiatry, Community Health Sciences, and Pediatrics, University of Calgary, Calgary, Alberta; Neurologist, Director, Calgary Tourette and Paediatric Movement Disorders Clinic, Calgary, Alberta. Hirsch, Lauren. Student, Community Health Sciences, University of Calgary, Calgary, Alberta. Gardner, David. Professor, Department of Psychiatry and Pharmacy, Dalhousie University, Halifax, Nova Scotia. Gorman, Daniel A. Assistant Professor, Department of Psychiatry, University of Toronto, Toronto, Ontario.
AN  - 25886656
AU  - Pringsheim,
AU  - T.
AU  - Hirsch,
AU  - L.
AU  - Gardner,
AU  - D.
AU  - Gorman,
AU  - D.
AU  - A.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/070674371506000203
DP  - Ovid Technologies
J2  - Can J Psychiatry
KW  - Adolescent
KW  - *Aggression/de [Drug Effects]
KW  - *Anticonvulsants/pd [Pharmacology]
KW  - *Antimanic Agents/pd [Pharmacology]
KW  - *Antipsychotic Agents/pd [Pharmacology]
KW  - *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy]
KW  - *Attention Deficit and Disruptive Behavior Disorders/dt [Drug Therapy]
KW  - Child
KW  - *Conduct Disorder/dt [Drug Therapy]
KW  - Humans
KW  - 0 (Anticonvulsants)
KW  - 0 (Antimanic Agents)
KW  - 0 (Antipsychotic Agents)
L1  - internal-pdf://4293043334/Pringsheim-2015-The pharmacological management.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Pringsheim, Tamara Hirsch, Lauren Gardner, David Gorman, Daniel A
PY  - 2015
SP  - 52-61
T2  - Canadian Journal of Psychiatry - Revue Canadienne de Psychiatrie
TI  - The pharmacological management of oppositional behaviour, conduct problems, and aggression in children and adolescents with attention-deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: a systematic review and meta-analysis. Part 2: antipsychotics and traditional mood stabilizers
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25886656http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25886656&amp;id=doi:&amp;issn=0706-7437&amp;isbn=&amp;volume=60&amp;issue=2&amp;spage=52&amp;pages=52-61&amp;date=2015&amp;title=Canadian+Journal+of+Psychiatry+-+Revue+Canadienne+de+Psychiatrie&amp;atitle=The+pharmacological+management+of+oppositional+behaviour%2C+conduct+problems%2C+and+aggression+in+children+and+adolescents+with+attention-deficit+hyperactivity+disorder%2C+oppositional+defiant+disorder%2C+and+conduct+disorder%3A+a+systematic+review+and+meta-analysis.+Part+2%3A+antipsychotics+and+traditional+mood+stabilizers.&amp;aulast=Pringsheim&amp;pid=%3Cauthor%3EPringsheim+T%3C%2Fauthor%3E%3CAN%3E25886656%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344947/pdf/cjp-2015-vol60-february-52-61.pdf
VL  - 60
ER  -
TY  - JOUR
AB  - Cognitive-behavioral therapy (CBT) has been developed and modified to treat anxiety symptoms in youth with high-functioning autism spectrum disorders (ASD) but has yielded varying findings. 

The present report is a systematic review and meta-analysis examining the efficacy of CBT for anxiety among youth with ASD. A systematic search identified 14 studies involving 511 youth with high-functioning ASD. 

A random effects meta-analysis yielded a statistically significant pooled treatment effect size (g) estimate for CBT (g = -0.71, p &lt; .001) with significant heterogeneity [Q (13) = 102.27, p &lt; .001]. Removal of a study outlier yielded a statistically significant pooled treatment effect size, (g = -0.47, p &lt; .001). Anxiety informant and treatment modality were not statistically significant moderators of treatment response. 

Findings suggest that CBT demonstrates robust efficacy in reducing anxiety symptoms in youth with high-functioning ASD.
AD  - Ung, Danielle. Department of Psychology, University of South Florida, 4202 E. Fowler Ave., PCD 4118G, Tampa, FL, 33620-7200, USA, danielleung@mail.usf.edu.
AN  - 25246292
AU  - D.
AU  - Ung
AU  - R.
AU  - Selles
AU  - B.
AU  - J.
AU  - Small
AU  - E.
AU  - A.
AU  - Storch
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10578-014-0494-y
DP  - Ovid Technologies
J2  - Child Psychiatry Hum Dev
KW  - Adolescent
KW  - Anxiety Disorders/di [Diagnosis]
KW  - Anxiety Disorders/px [Psychology]
KW  - *Anxiety Disorders/th [Therapy]
KW  - Autism Spectrum Disorder/di [Diagnosis]
KW  - Autism Spectrum Disorder/px [Psychology]
KW  - *Autism Spectrum Disorder/th [Therapy]
KW  - Child
KW  - Child Development Disorders, Pervasive/th [Therapy]
KW  - *Cognitive Therapy/mt [Methods]
KW  - Family Therapy/mt [Methods]
KW  - Female
KW  - Humans
KW  - Intelligence
KW  - Male
KW  - Psychotherapy, Group/mt [Methods]
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
L1  - internal-pdf://1371986445/Ung-2015-A Systematic Review and Meta-Analysis.pdf
LA  - English
M3  - Comparative Study Meta-Analysis Review
N1  - Ung, Danielle Selles, Robert Small, Brent J Storch, Eric A
PY  - 2015
SP  - 533-47
T2  - Child Psychiatry &amp; Human Development
TI  - A Systematic Review and Meta-Analysis of Cognitive-Behavioral Therapy for Anxiety in Youth with High-Functioning Autism Spectrum Disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25246292http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25246292&amp;id=doi:10.1007%2Fs10578-014-0494-y&amp;issn=0009-398X&amp;isbn=&amp;volume=46&amp;issue=4&amp;spage=533&amp;pages=533-47&amp;date=2015&amp;title=Child+Psychiatry+%26+Human+Development&amp;atitle=A+Systematic+Review+and+Meta-Analysis+of+Cognitive-Behavioral+Therapy+for+Anxiety+in+Youth+with+High-Functioning+Autism+Spectrum+Disorders.&amp;aulast=Ung&amp;pid=%3Cauthor%3EUng+D%3C%2Fauthor%3E%3CAN%3E25246292%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007/s10578-014-0494-y
UR  - http://download.springer.com/static/pdf/314/art%253A10.1007%252Fs10578-014-0494-y.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10578-014-0494-y&amp;token2=exp=1489074468~acl=%2Fstatic%2Fpdf%2F314%2Fart%25253A10.1007%25252Fs10578-014-0494-y.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10578-014-0494-y*~hmac=10f11a58614482d7a45432a851027cf254a733c235e2e75b162d34bffa7ffab5
VL  - 46
ER  -
TY  - JOUR
AB  - **OBJECTIVE:**
To systematically review and integrate data on the neurodevelopmental outcome of children after administration of a single course of antenatal corticosteroids for threatened preterm labor.

**DATA SOURCES:**
MEDLINE, Scopus, CENTRAL, and www.clinicaltrials.gov (inception to August 2014) using combinations of the terms &ldquo;prenatal,&rdquo; &ldquo;antenatal,&rdquo; &ldquo;cortico*,&rdquo; &ldquo;*steroid*,&rdquo; &ldquo;betamethasone,&rdquo; &ldquo;dexamethasone,&rdquo; &ldquo;neurodevelopment*,&rdquo; &ldquo;*development*,&rdquo; and &ldquo;follow-up.&rdquo; We perused the references of the retrieved articles.

**METHODS OF STUDY SELECTION:**
We included randomized and nonrandomized trials reporting on the neurodevelopmental outcomes of children whose mothers were administered a single course of betamethasone or dexamethasone antenatally for threatened preterm birth as opposed to placebo or no treatment.

**TABULATION, INTEGRATION, AND RESULTS:**
Summary risk ratio (RR) was calculated for dichotomous data; standardized mean difference was calculated for trials that measured the same outcome but used different methods. Heterogeneity was assessed using the I2 statistic. Sensitivity and subgroup analyses were planned according to study design, specific steroid, and mean gestational age at birth. A single course of antenatal corticosteroids was associated with reduced risk for cerebral palsy (seven studies; treated: 390 of 5,199, untreated: 146 of 1,379; RR 0.678, 95% confidence interval [CI] 0.564&ndash;0.815), psychomotor development index less than 70 (two studies; treated: 783 of 3,049, untreated: 258 of 969; RR 0.829, 95% CI 0.737&ndash;0.933), and severe disability (five studies; treated: 1,567 of 4,840, untreated: 475 of 1,211; RR 0.787, 95% CI 0.729&ndash;0.850). Steroid treatment increased the rates of intact survival (six studies; treated: 1,082 of 2,013, untreated: 273 of 561; RR 1.186, 95% CI 1.056&ndash;1.332). Betamethasone was found to significantly decrease the risk for severe disability and increase the rate of intact survival. Dexamethasone increased the rate of intact survival; however, data for dexametasone and the other planned subgroup analyses were limited (fewer than 1,000 children at most). The major limitations involved inclusion of nonrandomized studies and scarcity of data on finer neurodevelopmental outcomes.

**CONCLUSION:**
A single course of antenatal corticosteroids in women at high risk for preterm birth appears to improve most neurodevelopmental outcomes in offspring born before 34 weeks of gestation.
AD  - Sotiriadis, Alexandros. Second Department of Obstetrics and Gynecology and the First Department of Neonatology and Intensive Care Unit, Aristotle University of Thessaloniki, Thessaloniki, and the Department of Obstetrics and Gynecology, University of Ioannina, Ioannina, Greece; the Cyprus International Institute for Environmental and Public Health, Cyprus University of Technology, Limassol, Cyprus; and the Center for Fetal Therapy, Johns Hopkins University, Baltimore, Maryland.
AN  - 26000510
AU  - Sotiriadis,
AU  - A.
AU  - Tsiami,
AU  - A.
AU  - Papatheodorou,
AU  - S.
AU  - Baschat,
AU  - A.
AU  - A.
AU  - Sarafidis,
AU  - K.
AU  - Makrydimas,
AU  - G.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/AOG.0000000000000748
DP  - Ovid Technologies
J2  - Obstet Gynecol
KW  - Betamethasone/ad [Administration &amp; Dosage]
KW  - *Cerebral Palsy/ep [Epidemiology]
KW  - Cerebral Palsy/pc [Prevention &amp; Control]
KW  - Clinical Trials as Topic
KW  - *Developmental Disabilities/ep [Epidemiology]
KW  - Developmental Disabilities/pc [Prevention &amp; Control]
KW  - Dexamethasone/ad [Administration &amp; Dosage]
KW  - Female
KW  - Gestational Age
KW  - *Glucocorticoids/ad [Administration &amp; Dosage]
KW  - Humans
KW  - Infant, Newborn
KW  - *Infant, Premature/gd [Growth &amp; Development]
KW  - Odds Ratio
KW  - Pregnancy
KW  - *Premature Birth/dt [Drug Therapy]
KW  - Severity of Illness Index
KW  - 0 (Glucocorticoids)
KW  - 7S5I7G3JQL (Dexamethasone)
KW  - 9842X06Q6M (Betamethasone)
L1  - internal-pdf://0571065223/Sotiriadis-2015-Neurodevelopmental Outcome Aft.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Sotiriadis, Alexandros Tsiami, Alexandra Papatheodorou, Stefania Baschat, Ahmet A Sarafidis, Kosmas Makrydimas, George 00006250-201506000-00018
PY  - 2015
SP  - 1385-96
T2  - Obstetrics &amp; Gynecology
TI  - Neurodevelopmental Outcome After a Single Course of Antenatal Steroids in Children Born Preterm: A Systematic Review and Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26000510http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26000510&amp;id=doi:10.1097%2FAOG.0000000000000748&amp;issn=0029-7844&amp;isbn=&amp;volume=125&amp;issue=6&amp;spage=1385&amp;pages=1385-96&amp;date=2015&amp;title=Obstetrics+%26+Gynecology&amp;atitle=Neurodevelopmental+Outcome+After+a+Single+Course+of+Antenatal+Steroids+in+Children+Born+Preterm%3A+A+Systematic+Review+and+Meta-analysis.&amp;aulast=Sotiriadis&amp;pid=%3Cauthor%3ESotiriadis+A%3C%2Fauthor%3E%3CAN%3E26000510%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCJCKBLEFH00/fs046/ovft/live/gv023/00006250/00006250-201506000-00018.pdf
VL  - 125
ER  -
TY  - JOUR
AB  - Bullying is a serious public health problem, and many studies have examined the effect of school-based anti-bullying programs. However, these programs and those outcomes are complex, broad, and diverse. 

Research is needed into the optimal strategies for these comprehensive programs, which consider both the effectiveness and cost of programs. We performed a meta-analysis of 13 studies using the Comprehensive Meta-Analysis software package to calculate effect size (ES) and the Q statistic. 

We conducted subgroup analyses to examine the differences based on student grade level, program duration, and program strategy. The pooled ES calculation indicated that school-based anti-bullying programs have a small to moderate effect on victimization. 

The results of the Q test indicated significant heterogeneity across studies of victimization (Q = 39.625; I (2) = 69.7%; p &lt; .001). Studies involving training in emotional control (p &lt; .01), peer counseling (p &lt; .05), or the establishment of a school policy on bullying (p &lt; .05) showed significantly larger ESs on victimization than did studies that did not involve these strategies. 

Effective school-based anti-bullying programs should include training in emotional control, peer counseling, and the establishment of a school policy on bullying. 

Copyright &copy; The Author(s) 2013.
AD  - Lee, Sunhee. Catholic University, Republic of Korea. Kim, Chun-Ja. Ajou University, Republic of Korea. Kim, Dong Hee. Sungshin University, Republic of Korea dhkim@sungshin.ac.kr.
AN  - 24092871
AU  - Lee,
AU  - S.
AU  - Kim,
AU  - C.
AU  - J.
AU  - Kim,
AU  - D.
AU  - H.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1367493513503581
DP  - Ovid Technologies
J2  - J Child Health Care
KW  - *Bullying/pc [Prevention &amp; Control]
KW  - Crime Victims/px [Psychology]
KW  - Humans
KW  - Peer Group
KW  - Policy Making
KW  - Program Evaluation
KW  - Randomized Controlled Trials as Topic
KW  - *School Health Services
KW  - Social Environment
KW  - *Students/px [Psychology]
L1  - internal-pdf://0192361575/Lee-2015-A meta-analysis of the effect of scho.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Lee, Sunhee Kim, Chun-Ja Kim, Dong Hee 1367493513503581
PY  - 2015
SP  - 136-53
T2  - Journal of Child Health Care
TI  - A meta-analysis of the effect of school-based anti-bullying programs
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24092871http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24092871&amp;id=doi:10.1177%2F1367493513503581&amp;issn=1367-4935&amp;isbn=&amp;volume=19&amp;issue=2&amp;spage=136&amp;pages=136-53&amp;date=2015&amp;title=Journal+of+Child+Health+Care&amp;atitle=A+meta-analysis+of+the+effect+of+school-based+anti-bullying+programs.&amp;aulast=Lee&amp;pid=%3Cauthor%3ELee+S%3C%2Fauthor%3E%3CAN%3E24092871%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 19
ER  -
TY  - JOUR
AB  - This study is a critical analysis of the association between selective serotonin reuptake inhibitors (SSRIs) exposure during pregnancy and autism spectrum disorder (ASD) risk in children. 

Electronic databases were searched for observational studies published from January 1946 to June 2014 related to the association between SSRI exposure during pregnancy and ASD in children. Studies relevant to the association between SSRI exposure during pregnancy and ASD in children were extracted and compiled for meta-analysis evaluation. Ninety-five citations were identified and seven observational studies were included. 

Four case-control studies were eligible for the meta-analysis and two cohort studies were narratively reviewed. The pooled crude and adjusted odds ratios of the case-control studies were 2.13 (95% CI 1.66-2.73) and 1.81 (95% CI 1.47-2.24) respectively. 

Low heterogeneity was observed between studies. The two population-based cohort studies, utilizing the same Denmark data set, have conflicting results. 

The findings of this meta-analysis and narrative review support an increased risk of ASD in children of mothers exposed to SSRIs during pregnancy; however, the causality remains to be confirmed. 

(PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract).
AD  - C Y L K Wong, Ian C. K.: wongick@hku.hk Wong, Ian C. K.: Department of Pharmacology, Li Ka Shing Faculty of Medicine, University of Hong Kong, 2/F Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong, wongick@hku.hk Man, Kenneth K. C.: Centre for Safe Medication Practice, Department of Pharmacology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China Tong, Henry H. Y.: School of Health Sciences, Rua de Luis Gonzaga Gomes, Macao Polytechnic Institute, Macao Wong, Lisa Y. L.: Centre for Safe Medication Practice, Department of Pharmacology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China Chan, Esther W.: Centre for Safe Medication Practice, Department of Pharmacology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China Simonoff, Emily: Kings College London, Institute of Psychiatry, Centre for Mental Health, London, United Kingdom Wong, Ian C. K.: Centre for Safe Medication Practice, Department of Pharmacology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China
AN  - 2015-04382-009
AU  - Man,
AU  - K.
AU  - K.
AU  - Tong,
AU  - H.
AU  - H.
AU  - Wong,
AU  - L.
AU  - Y.
AU  - Chan,
AU  - E.
AU  - W.
AU  - Simonoff,
AU  - E.
AU  - Wong,
AU  - I.
AU  - C.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.neubiorev.2014.11.020
DP  - Ovid Technologies
KW  - SSRI, Serotonin reuptake inhibitor, Autism spectrum disorder, Pregnancy *Autism *Pregnancy *Prenatal Exposure *Serotonin Reuptake Inhibitors Causality Psychopharmacology [2580] Developmental Disorders &amp; Autism [3250] Human Animal
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2015
SP  - 82-89
T2  - Neuroscience and Biobehavioral Reviews
TI  - Exposure to selective serotonin reuptake inhibitors during pregnancy and risk of autism spectrum disorder in children: A systematic review and meta-analysis of observational studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2015-04382-009 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.neubiorev.2014.11.020&amp;issn=0149-7634&amp;isbn=&amp;volume=49&amp;issue=&amp;spage=82&amp;pages=82-89&amp;date=2015&amp;title=Neuroscience+and+Biobehavioral+Reviews&amp;atitle=Exposure+to+selective+serotonin+reuptake+inhibitors+during+pregnancy+and+risk+of+autism+spectrum+disorder+in+children%3A+A+systematic+review+and+meta-analysis+of+observational+studies.&amp;aulast=Man&amp;pid=%3Cauthor%3EMan%2C+Kenneth+K.+C%3C%2Fauthor%3E%3CAN%3E2015-04382-009%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0149763414003248/1-s2.0-S0149763414003248-main.pdf?_tid=5b662c3c-18a9-11e5-a9ed-00000aacb362&amp;acdnat=1434955316_df2f5c7d4f823ea2fb741a0d51b1232a
VL  - 49
ER  -
TY  - JOUR
AB  - Although under-diagnosed, anxiety and depression are among the most prevalent psychiatric disorders in children and adolescents, leading to severe impairment, increased risk of future psychiatric problems, and a high economic burden to society. Universal prevention may be a potent way to address these widespread problems. 

There are several benefits to universal relative to targeted interventions because there is limited knowledge as to how to screen for anxiety and depression in the general population. Earlier meta-analyses of the prevention of depression and anxiety symptoms among children suffer from methodological inadequacies such as combining universal, selective, and indicated interventions in the same analyses, and comparing cluster-randomized trials with randomized trials without any correction for clustering effects. 

The present meta-analysis attempted to determine the effectiveness of universal interventions to prevent anxiety and depressive symptoms after correcting for clustering effects. 

A systematic search of randomized studies in PsychINFO, Cochrane Library, and Google Scholar resulted in 30 eligible studies meeting inclusion criteria, namely peer-reviewed, randomized or cluster-randomized trials of universal interventions for anxiety and depressive symptoms in school-aged children. 

Sixty-three percent of the studies reported outcome data regarding anxiety and 87 % reported outcome data regarding depression. Seventy percent of the studies used randomization at the cluster level. 

There were small but significant effects regarding anxiety (.13) and depressive (.11) symptoms as measured at immediate posttest. At follow-up, which ranged from 3 to 48 months, effects were significantly larger than zero regarding depressive (.07) but not anxiety (.11) symptoms. 

There was no significant moderation effect of the following pre-selected variables: the primary aim of the intervention (anxiety or depression), deliverer of the intervention, gender distribution, children&#039;s age, and length of the intervention. 

Despite small effects, we argue for the possible clinical and practical significance of these programs. Future evaluations should carefully investigate the moderators and mediators of program effects to identify active program components.
AD  - Ahlen, Johan. Department of Psychology, Uppsala University, Box 1225, 751 42, Uppsala, Sweden. johan.ahlen@psyk.uu.se. Lenhard, Fabian. Department of Clinical Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden. Ghaderi, Ata. Department of Clinical Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.
AN  - 26502085
AU  - Ahlen,
AU  - J.
AU  - Lenhard,
AU  - F.
AU  - Ghaderi,
AU  - A.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10935-015-0405-4
DP  - Ovid Technologies
J2  - J Prim Prev
KW  - Adolescent
KW  - *Anxiety Disorders/pc [Prevention &amp; Control]
KW  - Child
KW  - *Community Mental Health Services/mt [Methods]
KW  - Community Mental Health Services/og [Organization &amp; Administration]
KW  - Databases, Bibliographic
KW  - *Depressive Disorder/pc [Prevention &amp; Control]
KW  - Humans
KW  - *Outcome and Process Assessment (Health Care)
KW  - Randomized Controlled Trials as Topic
KW  - School Health Services/og [Organization &amp; Administration]
KW  - *School Health Services
L1  - internal-pdf://1233550043/Ahlen-2015-Universal Prevention for Anxiety an.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Ahlen, Johan Lenhard, Fabian Ghaderi, Ata 10.1007/s10935-015-0405-4
PY  - 2015
SP  - 387-403
T2  - Journal of Primary Prevention
TI  - Universal Prevention for Anxiety and Depressive Symptoms in Children: A Meta-analysis of Randomized and Cluster-Randomized Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26502085http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26502085&amp;id=doi:10.1007%2Fs10935-015-0405-4&amp;issn=0278-095X&amp;isbn=&amp;volume=36&amp;issue=6&amp;spage=387&amp;pages=387-403&amp;date=2015&amp;title=Journal+of+Primary+Prevention&amp;atitle=Universal+Prevention+for+Anxiety+and+Depressive+Symptoms+in+Children%3A+A+Meta-analysis+of+Randomized+and+Cluster-Randomized+Trials.&amp;aulast=Ahlen&amp;pid=%3Cauthor%3EAhlen+J%3C%2Fauthor%3E%3CAN%3E26502085%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://link.springer.com/article/10.1007%2Fs10935-015-0405-4
UR  - http://download.springer.com/static/pdf/658/art%253A10.1007%252Fs10935-015-0405-4.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10935-015-0405-4&amp;token2=exp=1489074531~acl=%2Fstatic%2Fpdf%2F658%2Fart%25253A10.1007%25252Fs10935-015-0405-4.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10935-015-0405-4*~hmac=5ef83fb3e215834ca74481a2cc79fb803924c9880304728fa3a13f4d54375af4
VL  - 36
ER  -
TY  - JOUR
AB  - Overviews of systematic reviews (OSRs) provide rapid access to high quality, consolidated research evidence about prevention intervention options, supporting evidence-informed decision-making, and the identification of fruitful areas of new research. 

This OSR addressed three questions about prevention strategies for child and adolescent anxiety: (1) Does the intervention prevent anxiety diagnosis and/or reduce anxiety symptoms compared to passive controls? (2) Is the intervention equal to or more effective than active controls? (3) What is the evidence quality (EQ) for the intervention? 

Prespecified inclusion criteria identified systematic reviews and meta-analyses (2000-2014) with an AMSTAR quality score &gt; 3/5. EQ was rated using Oxford evidence levels EQ1 (highest) to EQ5 (lowest). Three reviews met inclusion criteria. One narrative systematic review concluded school-based interventions reduce anxiety symptoms. One meta-analysis pooled 65 randomized controlled trials (RCTs; any intervention) and reported a small, statistically significant reduction in anxiety symptoms and diagnosis incidence. 

Neither review provided pooled effect size estimates for specific intervention options defined by type (i.e., universal/selective/indicated), intervention content, or comparison group (i.e., passive/active control), thus precluding EQ ratings. 

One meta-analysis pooled trials of vigorous exercise and reported small, nonstatistically significant reductions in anxiety symptoms for comparisons against passive and active controls (EQ1). Better use of primary studies in meta-analyses, including program-specific pooled effect size estimates and network meta-analysis is needed to guide evidence-informed anxiety prevention program choices. RCTs of innovative community/primary care based interventions and web-based strategies can fill knowledge gaps. 

Copyright &copy; 2015 Wiley Periodicals, Inc.
AD  - Bennett, Kathryn. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada. Manassis, Katharina. Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada. Duda, Stephanie. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada. Bagnell, Alexa. Department of Psychiatry, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia, Canada. Bernstein, Gail A. Department of Psychiatry, University of Minnesota, Minneapolis, Minnesota. Garland, E Jane. Department of Psychiatry, BC Children&#039;s Hospital, University of British Columbia, Vancouver, British Columbia, Canada. Miller, Lynn D. Department of Educational and Counselling Psychology and Special Education, University of British Columbia, Vancouver, British Columbia, Canada. Newton, Amanda. Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada. Thabane, Lehana. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada. Wilansky, Pamela. Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
AN  - 26282454
AU  - Bennett,
AU  - K.
AU  - Manassis,
AU  - K.
AU  - Duda,
AU  - S.
AU  - Bagnell,
AU  - A.
AU  - Bernstein,
AU  - G.
AU  - A.
AU  - Garland,
AU  - E.
AU  - J.
AU  - Miller,
AU  - L.
AU  - D.
AU  - Newton,
AU  - A.
AU  - Thabane,
AU  - L.
AU  - Wilansky,
AU  - P.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/da.22400
DP  - Ovid Technologies
J2  - Depress Anxiety
KW  - Adolescent
KW  - *Anxiety Disorders/pc [Prevention &amp; Control]
KW  - Child
KW  - Female
KW  - Humans
KW  - Male
KW  - School Health Services
L1  - internal-pdf://2505806114/Bennett-2015-Preventing Child and Adolescent A.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Bennett, Kathryn Manassis, Katharina Duda, Stephanie Bagnell, Alexa Bernstein, Gail A Garland, E Jane Miller, Lynn D Newton, Amanda Thabane, Lehana Wilansky, Pamela
PY  - 2015
SP  - 909-18
T2  - Depression and Anxiety
TI  - Preventing Child and Adolescent Anxiety Disorders: Overview of Systematic Reviews
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26282454http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26282454&amp;id=doi:10.1002%2Fda.22400&amp;issn=1091-4269&amp;isbn=&amp;volume=32&amp;issue=12&amp;spage=909&amp;pages=909-18&amp;date=2015&amp;title=Depression+%26+Anxiety&amp;atitle=PREVENTING+CHILD+AND+ADOLESCENT+ANXIETY+DISORDERS%3A+OVERVIEW+OF+SYSTEMATIC+REVIEWS.&amp;aulast=Bennett&amp;pid=%3Cauthor%3EBennett+K%3C%2Fauthor%3E%3CAN%3E26282454%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1002/da.22400/asset/da22400.pdf?v=1&amp;t=j02kysxw&amp;s=0765a082b75a82d16e33a2c8be16f4643090e780
VL  - 32
ER  -
TY  - JOUR
AB  - An emerging body of research demonstrates the effectiveness of Acceptance and Commitment Therapy (ACT) in the treatment of adult psychopathology, with several reviews and meta-analyses attesting to its effectiveness. 

While there are comparatively fewer empirical studies of child populations, the past few years has seen burgeoning research interest in the utility of ACT for problems in childhood. 

A systematic review of the published and unpublished literature was conducted to examine the evidence for ACT in the treatment of children and to provide support for clinical decision making in this area. Searches of PsycInfo, PsycArticles, PsycExtra, Proquest and the Association for Contextual Behavioral Science databases were undertaken, as well as reference lists and citation searches conducted, up to December 2014. 

Broad inclusion criteria were employed to maximise review breadth. Methodological quality was assessed and a narrative synthesis approach adopted. Twenty-one studies covering a spectrum of presenting problems met inclusion criteria, with a total of 707 participants. Studies were predominantly within-group designs, with a lesser proportion of case studies/series, between-group and randomised controlled trials. 

The preponderance of evidence suggests ACT results in improvements in clinician, parent and self-reported measures of symptoms, quality of life outcomes and/or psychological flexibility, with many studies demonstrating further gains at follow-up assessment. However, several methodological weaknesses limit conclusions, including small samples, non-randomised designs, and few alternative treatment or control comparisons. 

While larger scale, methodologically rigorous trials from a broader research teams are needed to consolidate these preliminary findings, emerging evidence suggests ACT is effective in the treatment of children across a multitude of presenting problems. ACT may be a viable alternative treatment option for clinicians working with young people. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AN  - 2017-01152-002
AU  - Swain,
AU  - J.
AU  - Hancock,
AU  - K.
AU  - Dixon,
AU  - A.
AU  - Bowman,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jcbs.2015.02.001
L1  - internal-pdf://1004855506/Swain-2015-Acceptance and Commitment Therapy f.pdf
PY  - 2015
SP  - 73-85
TI  - Acceptance and Commitment Therapy for children: A systematic review of intervention studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2017-01152-002
VL  - 4
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
Youth drug abuse is a severe problem worldwide, and the use of cannabis, amphetamine, ecstasy and cocaine (referred to here as non-opioid drugs) is strongly associated with a range of health and social problems. This review focuses on drug abuse that is severe enough to warrant treatment. The population of interest is young people who are receiving MDFT specifically for non-opioid drug abuse. MDFT is a manual-based family therapy approach that focuses on individual characteristics of the young person, the parents, and other key individuals in the young person&rsquo;s life, as well as on the relational patterns contributing to the drug abuse and other problem behaviors. A variety of therapeutic techniques are used to improve the young person and the family&rsquo;s behaviors, attitudes, and functioning across the variety of domains. MDFT aims to reorient the young person and his/her family towards a more functional developmental trajectory based on key principles that include: 1) Individual biological, social, cognitive, personality, interpersonal, familial, developmental, and social ecological aspects can all contribute to the development, continuation, worsening and chronicity of drug problems; 2) The relationships with parent(s), siblings and other family members are fundamental domains of assessment and change; 3) Change is multifaceted, multi-determined and relates to the youths&rsquo; cognitive and psychosocial developmental stages; 4) Motivation is not assumed, but is malleable; and motivating the young person and his or her family members about treatment participation and change is a fundamental therapeutic task; 5) Multiple therapeutic alliances are required to create a foundation for change; and 6) Therapist responsibility and attitude is fundamental to success (Liddle, 2010). 

**OBJECTIVES** 
The main objectives of this review are to evaluate the current evidence on the effects of MDFT on drug abuse reduction for young people (aged 11-21 years) in treatment for non-opioid drug abuse, and if possible to examine moderators of drug abuse reduction effects, specifically analysing whether MDFT works better for particular types of participants. 

**SEARCH STRATEGY** 
An extensive search strategy was used to identify qualifying studies. Searches were run in October 2014. A wide range of electronic bibliographic databases were searched along with government and policy databanks, grey literature databases, citations in other reviews and the included primary studies, hand searching in relevant journals, and Internet searches using Google. We also maintained correspondence with researchers in the field of MDFT. No language or date restrictions were applied to the searches. 

**SELECTION CRITERIA** 
To be eligible for inclusion, studies must: &bull; have involved a manual-based outpatient MDFT drug treatment for young people aged 11-21 years enrolled for non-opioid drug abuse; &bull; have used experimental, quasi-experimental or non-randomized controlled designs; &bull; have reported at least one of the following eligible outcome variables: abstinence, reduction of drug abuse, family functioning, education or vocational involvement, retention, risk behavior or any other adverse effect; &bull; not have focused exclusively on treating mental disorders; and &bull; have had MDFT as the primary intervention. 

**DATA COLLECTION AND ANALYSIS** 
The literature search yielded a total of 6,519 references, of which 170 studies were deemed potentially relevant and retrieved for eligibility determination. Of these, 16 papers describing five unique studies were included in the final review. Meta-analysis was used to examine the effects of MDFT on drug usage (measured by both frequency and problem severity), on education and on treatment retention. It was not possible to perform a meta-analysis on family functioning, risk behavior or other adverse effects, nor was it possible to assess moderators of drug abuse reduction effects, or whether MDFT works better for particular types of participants. 

**RESULTS** 
Not all the studies provided data that enabled the calculation f compar ble effect sizes on the different outcomes. Two studies had two comparison groups with different individuals, and we performed separate analyses including the different control groups where these two studies provided relevant outcome measures. The most conservative effects for the different outcomes are reported in the following. All outcomes are measured as decreases; hence a negative effect size favours MDFT. Meta-analysis of the five included studies showed a small effect (around 30 percent of a standard deviation for the different control combinations) of MDFT for reduction in youth drug abuse problem severity at 6 months post-intake (SMD=-0.30 (95% CI -0.53 to -0.07, p=0.01 compared to Cognitive Behavioral Therapy (CBT), peer group, treatment as usual (TAU), multifamily educational therapy (MEI) and Adolescent Community Reinforcement Approach (ACRA)). At 12 months post-intake meta-analysis of the five included studies showed a small effect (around 20 percent of a standard deviation for the different control combinations) of MDFT for reduction in youth drug abuse problem severity (SMD=-0.23 95% CI -0.39 to -0.06, p=0.007 compared to CBT, peer group, TAU, adolescent group therapy (AGT) and ACRA). Pooled results of the four studies providing data on drug abuse frequency reduction favoured MDFT. The effect of MDFT for youth drug abuse frequency reduction was small at 6 months post-intake (overall around 20 percent of a standard deviation for the different control combinations) (SMD = -0.24; 95% CI -0.43 to -0.06; p=0.01 compared to CBT, peer group, TAU and MET/CBT5). It was not statistically significant at 12 month follow-up compared to CBT, peer group, TAU and MET/CBT5/ACRA. Two studies reported on school grades as an outcome, providing data at 6 months post-intake only. Meta-analysis favored MDFT when the controls used in the analysis were peer group and MEI (SMD = -0.47; 95% CI -0.92, -0.01; p=0.05). It was not statistically significant when the comparisons used in the analysis were peer group and AGT. We extracted data on retention from all five included studies. Meta-analysis favoured MDFT for retention of participants for all the different control combinations (OR = 0.44; 95% CI 0.21 to 0.94; p=0.03 compared to CBT, peer group, TAU, AGT and MET/CBT5). Overall the results indicated that retention may be positively affected by structured MDFT treatment compared to less structured control conditions. 


**AUTHORS&rsquo; CONCLUSIONS** 
The available data support the hypothesis that, compared with certain other active treatments, MDFT reduces the severity of drug abuse among youth. The treatments MDFT was compared against in the included studies were Cognitive Behavioral Therapy (CBT), peer group, treatment as usual (TAU), adolescent group therapy (AGT)/multifamily educational therapy (MEI) and Motivational Enhancement Therapy/Cognitive Behavioral Therapy (MET/CBT5)/Adolescent Community reinforcement approach (ACRA). Furthermore, the available data support the hypothesis that there is a reduction in the frequency of drug abuse when treating young drug abusers with MDFT compared to CBT, peer group, TAU and MET/CBT5/ACRA at 6 months post-intake, but the effect is not statistically significant 12 months after intake. The number of studies providing data that allowed calculation of an effect size for drug abuse reduction was limited, however, and this should be considered when interpreting these results. The conclusions that can be drawn about MDFT as an effective treatment for young drug abusers compared to other treatments would be more convincing if more studies were available. The pooled effect sizes are small and confidence intervals are often close to zero. The statistically significance of the pooled results on severity of drug abuse among youth 6 months post-intake is sensitive to the removal of studies with methodological weaknesses. Overall, the results also indicate that retention may be positively affected by structured MDFT treatment compared to CBT, peer group, TAU, AGT/MEI and MET/CBT5/ ACRA which are all less-structure control conditions. However, the results must be interpreted with caution as two studies stand out from the others; here the effect sizes are large, confidence intervals are wide, and the estimated between study variation is relatively large. The main conclusion of this review is that there is insufficient firm evidence of the effectiveness of MDFT, especially with regard to moderators of drug abuse reduction effects, and whether MDFT works better for particular types of participants. While additional research is needed, the review does, however, offer support that MDFT treatment to young non-opioid drug abusers reduce their drug abuse somewhat more than CBT, peer group, TAU, AGT/MEI and MET/CBT5/ACRA.
AU  - Filges,
AU  - T.
AU  - Rasmussen,
AU  - P.
AU  - S.
AU  - Andersen,
AU  - D.
AU  - Jørgensen,
AU  - A.
AU  - M.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2015.8
PY  - 2015
T2  - Campbell Systematic Reviews
TI  - Multidimensional Family Therapy (MDFT) for Young People in Treatment for Non-opioid Drug Use: A Systematic Review
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
Youth drug use is a severe problem worldwide, and the use of cannabis, amphetamine ecstasy and cocaine, referred to as non-opioid drugs, are strongly associated with a range of health and social problems. This review focuses on Family Behavior Therapy (FBT) as a treatment for young people who misuse non-opioid drugs. FBT is a manual-based family therapy approach. The program is behavior and skill-oriented. It is concerned with identifying psychological and situational stimuli and triggers presumed to be directly related to the youth&rsquo;s drug use, and skills training to improve self-control. FBT is designed to accommodate diverse populations of youth with a variety of behavioral, cultural and individual preferences. FBT incorporates behavioral theory (reduction of undesired behavior by manipulating external reinforcement), structural family theory (in which the structure of the family influence the youth&rsquo;s behavior) and strategic family theory (where treatment methods are problem-focused and pragmatic). 

**OBJECTIVES** 
The main objective of this review is to evaluate the current evidence on the effects of FBT on reduction of drug use frequency for young people in outpatient treatment for non-opioid drug use and, if possible, to examine moderators of drug use reduction effects, specifically analyzing whether FBT works better for particular types of participants. 

**SEARCH STRATEGY** 
A relatively narrow search strategy to identify qualifying studies was performed. A wide range of electronic bibliographic databases were searched along with government and policy databanks, grey literature databases, citations in other reviews and in the included primary studies, hand searches of relevant journals, and Internet searches using Google. We also corresponded with researchers in the FBT field. Neither language nor date restrictions were applied to the searches. 

**SELECTION CRITERIA** 
Studies eligible for inclusion in the review are required to meet several eligibility criteria. Studies must: &bull; have involved a manual-based FBT treatment for young people aged 11-21 years enrolled in outpatient treatment for non-opioid drug use; &bull; have used experimental, quasi-experimental or non-randomized controlled designs; &bull; have reported at least one eligible outcome variable measuring abstinence, reduction of drug use, family functioning, education or vocational involvement, retention, risk behavior or any other adverse effects; &bull; not have focused exclusively on treating mental disorders; and &bull; have had FBT as the primary intervention. 

**DATA COLLECTION AND ANALYSIS** 
The literature search yielded a total of 10,779 records which were screened for eligibility based on title and abstract. 99 potentially relevant records were retrieved and screened in full text, of which 7 studies were potentially relevant. Of these, two studies were data-extracted by the authors and included in the review. Meta-analysis was performed to examine the effects of FBT on drug use reduction, family functioning and risk behavior. 

**RESULTS**
For the primary outcome of reduction in drug use frequency, measured at end of treatment, the standardized mean difference was 0.49 (95% CI -0.51, 1.50). At 12 month post-intake, Azrin et al. (2001) found no statistically significant difference between FBT and the comparison treatment, SMD=-0.03 (95% CI -0.58, 0.52). For family functioning, measured at end of treatment, the standardized mean difference was 0.58 (95% CI 0.02, 1.13) reported by parents and 0.29 (95% CI -0.72, 1.30) reported by youth. At 12 month post-intake, Azrin et al. (2001) found no statistically significant difference between FBT and the comparison treatment for parent satisfaction or youth satisfaction with family functioning, SMD= -0.30 (95% CI -0.86, 0.26) and SMD= 0.47 (95% CI -0.09, 1.04). For risk behavior, measured at end of treatment, the standardized mean difference was 0.29 (95% CI -0.16, 0.74). At 12 month post-intake, Azrin et al. (2001) finds a statistically significant difference that favors the comparison treatment, SMD= -0.56 (95% CI - .13, .00). Meta-analysis was not possible for the education outcomes as the measures are incomparable. None of the studies reported statistically significant effect sizes for school outcomes. Due to lack of data for the number randomized in both studies it is not possible to report effects for retention. No other adverse effects are reported in the studies. 

**AUTHORS&rsquo; CONCLUSIONS** 
The main conclusion of the review is that there is a lack of firm evidence on the effect of FBT. There is a need for more research, and particularly a need for more methodologically rigorous studies in the field of treatment for young drug users. The aim of this systematic review is to explore what is known about the effectiveness of FBT for the purpose of reducing youth drug use, in order to contribute to an evidence-based approach in the treatment of young non-opioid drug users. The evidence found does not provide a basis for drawing conclusions about actual outcomes and impacts. Consequently, no substantive conclusion about the effectiveness can be made, resulting in neither support nor rejection of the present FBT treatment approach.
AU  - Lindstrøm,
AU  - M.
AU  - Saidj,
AU  - M.
AU  - Kowalski,
AU  - K.
AU  - Filges,
AU  - T.
AU  - Rasmussen,
AU  - P.
AU  - S.
AU  - Jørgensen,
AU  - A.
AU  - M.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2015.9
PY  - 2015
T2  - Campbell Systematic Reviews
TI  - Family Behavior Therapy (FBT) for Young People in Treatment for Illicit Non-opioid Drug Use: a Systematic Review
ER  -
TY  - JOUR
AB  - The alpha2-adrenergic receptor agonist guanfacine, in its extended-release formulation (GXR), is the most recent nonstimulant medication approved in several countries for the treatment of attention-deficit hyperactivity disorder (ADHD) as monotherapy and as adjunctive pharmacotherapy to stimulants in children and adolescents. 

The present paper aims to review comprehensively and critically the pharmacodynamic and pharmacokinetic characteristics and the published evidence on the efficacy and safety profile of GXR in the treatment of ADHD. A comprehensive search of relevant databases (PubMed, Embase, and PsycInfo) was conducted to identify studies published in peer-reviewed journals until January 15, 2015. 

Though the precise mechanism of action of guanfacine in the treatment of ADHD is not fully understood, it is thought to act directly by enhancing noradrenaline functioning via alpha2A-adrenoceptors in the prefrontal cortex. Weight-adjusted doses should be used, with a dosing regime on a milligram per kilogram basis, starting at doses in the range 0.05-0.08 mg/kg/day, up to 0.12 mg/kg/day. 

As evidenced in short-term randomized controlled trials and in long-term open-label extension studies, GXR has been shown to be effective as monotherapy in the treatment of ADHD. Furthermore, GXR has also been found to be effective as adjunctive therapy to stimulant medications in patients with suboptimal responses to stimulants. 

Many of the adverse reactions associated with GXR, particularly sedation-related effects, were dose-related, transient, mild to moderate in severity, and did not interfere with attention or overall efficacy. There are no reports of serious cardiovascular adverse events associated with GXR alone or in combination with psychostimulants.
AD  - Martinez-Raga, Jose. Teaching Unit of Psychiatry and Psychological Medicine, University Hospital Doctor Peset, University of Valencia, Valencia, Spain ; CEU Cardenal Herrera University, Valencia, Spain. Knecht, Carlos. Area de Salud Mental, Hospital Padre Jofre, Valencia, Spain. de Alvaro, Raquel. Hospital General, Consorcio Hospitalario Provincial, Castellon, Spain.
AN  - 26064054
AU  - Martinez-Raga,
AU  - J.
AU  - Knecht,
AU  - C.
AU  - de
AU  - Alvaro,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2147/NDT.S65735
DP  - Ovid Technologies
J2  - Neuropsychiatr
L1  - internal-pdf://2539875516/Martinez-2015-Profile of guanfacine extended r.pdf
LA  - English
M3  - Review
N1  - Martinez-Raga, Jose Knecht, Carlos de Alvaro, Raquel ndt-11-1359
PY  - 2015
SP  - 1359-70
T2  - Neuropsychiatric Disease and Treatment
TI  - Profile of guanfacine extended release and its potential in the treatment of attention-deficit hyperactivity disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=26064054http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26064054&amp;id=doi:10.2147%2FNDT.S65735&amp;issn=1176-6328&amp;isbn=&amp;volume=11&amp;issue=&amp;spage=1359&amp;pages=1359-70&amp;date=2015&amp;title=Neuropsychiatric+Disease+%26+Treatment&amp;atitle=Profile+of+guanfacine+extended+release+and+its+potential+in+the+treatment+of+attention-deficit+hyperactivity+disorder.&amp;aulast=Martinez-Raga&amp;pid=%3Cauthor%3EMartinez-Raga+J%3C%2Fauthor%3E%3CAN%3E26064054%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 11
ER  -
TY  - JOUR
AB  - **Objectives: **
To assess the efficacy of educational and skills-based interventions to prevent relationship and dating violence in adolescents and young adults. 

**Methods: **
We searched Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, CINAHL, PsycINFO, and other databases for randomized, cluster-randomized, and quasi-randomized studies of interventions to prevent relationship or dating violence. We conducted meta-analyses for episodes of relationship violence, behaviors, and attitudes. 

**Results: **
We included 38 studies (15,903 participants) in this review, of which we included 33 studies in the meta-analyses. The risk ratio for episodes of relationship violence was 0.77 (95% confidence interval [CI]: [0.53, 1.13]). The standardized mean difference (SMD) for attitudes toward relationship violence was 0.06 (95% CI: [-0.01, 0.15]). The SMD for behavior related to relationship violence was -0.07 (95% CI: [-0.31, 0.16]). Subgroup analyses showed no statistically significant differences by setting or type of participants. 

**Conclusions:** 
We found no evidence of effectiveness of interventions on episodes violence, attitudes or behaviors. 

(PsycINFO Database Record (c) 2015 APA, all rights reserved) (journal abstract).
AD  - Fellmeth, Gracia: gracia.fellmeth@nhs.net Fellmeth, Gracia: Oxford University, Old Road Campus, Headington, Oxford, United Kingdom, OX3 7LF, gracia.fellmeth@nhs.net Fellmeth, Gracia: Oxford University, Oxford, United Kingdom Heffernan, Catherine: NHS Hounslow, Hounslow, United Kingdom Nurse, Joanna: WHO Regional Office for Europe, Copenhagen, Denmark Habibula, Shakiba: Public Health, Buckinghamshire County Council, Aylesbury, United Kingdom Sethi, Dinesh: WHO Regional Office for Europe, Copenhagen, Denmark
AN  - 2014-56659-007
AU  - Fellmeth,
AU  - G.
AU  - Heffernan,
AU  - C.
AU  - Nurse,
AU  - J.
AU  - Habibula,
AU  - S.
AU  - Sethi,
AU  - D.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD004534.pub3
DP  - Ovid Technologies
KW  - dating violence, intimate partner violence, adolescents *Risk Factors *School Based Intervention *Social Dating *Violence Prevention Curriculum &amp; Programs &amp; Teaching Methods [3530] Human
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2015
SP  - 90-102
T2  - Research on Social Work Practice
TI  - Educational and skills-based interventions to prevent relationship violence in young people
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2014-56659-007 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1049731514533392&amp;issn=1049-7315&amp;isbn=&amp;volume=25&amp;issue=1&amp;spage=90&amp;pages=90-102&amp;date=2015&amp;title=Research+on+Social+Work+Practice&amp;atitle=Educational+and+skills-based+interventions+to+prevent+relationship+violence+in+young+people.&amp;aulast=Fellmeth&amp;pid=%3Cauthor%3EFellmeth%2C+Gracia%3C%2Fauthor%3E%3CAN%3E2014-56659-007%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rsw.sagepub.com/content/25/1/90http://rsw.sagepub.com/content/25/1/90.full.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - **Bakgrunn** 
Lavt fysisk aktivitetsnivå er ofte forbundet med andre usunne levevaner, som dårlig kosthold og røyking. I det forebyggende og helsefremmende arbeidet kan det derfor være hensiktsmessig å rette innsatsen mot flere levevaner samtidig, for eksempel i kampanjer rettet mot større befolkningsgrupper. Denne rapporten gir en oversikt over forskning om effekt av befolkningsrettede opplysnings- og motivasjonstiltak for økt fysisk aktivitet og endring i &eacute;n eller flere andre levevaner. Målet er å utarbeide en systematisk oversikt over effektstudier som har evaluert 1) opplysnings- og motivasjonstiltak rettet mot fysisk aktivitet og &eacute;n eller flere andre levevaner 2) opplysnings- og motivasjonstiltak rettet mot fysisk aktivitet alene, men hvor effekten av tiltaket er målt også på andre levevaner. 

**Metode** 
Vi utførte et systematisk søk i relevante databaser, supplert med sjekk av referansene i relevante systematiske oversikter. Vi kontaktet også forfattere av protokoller og konferansesammendrag for å finne relevante effektstudier. Søk etter studier ble utført i desember 2012. To personer gikk uavhengig av hverandre igjennom alle referanser og vurderte disse for inklusjon. Alle referanser som ble vurdert som relevante opp mot våre inklusjonskriterier ble innhentet i fulltekst, og kvalitetsvurdert av to personer ved bruk av Kunnskapssenterets sjekkliste. Vi inkluderte alle studier som møtte våre inklusjonskriterier. Tiltakene skulle være &laquo;befolkningsrettede&raquo;, dvs. rettet mot en større gruppe mennesker (barn, voksne eller eldre). Relevante utfallsmål var: helse, holdninger, mestring, kunnskap, helseatferd, bruk av helsetjenester og kostnader. To personer hentet ut data. Der det var hensiktsmessig ble resultater slått sammen i meta-analyse. Kvaliteten på den samlede dokumentasjonen ble vurdert ved hjelp av GRADE (Grading of Recommendations, Assessment, Development, and Evaluation). 

**Resultat** 
De fleste tiltakene var komplekse i den forstand at de rettet seg mot flere befolkningsgrupper og flere levevaner, og benyttet flere virkemidler samtidig. Tiltakene var gitt til familier/lokalsamfunn, i skole, ved arbeidsplass, trossamfunn, fritidsaktiviteter. Tiltakene omhandlet to til fem levevaner i tillegg til fysisk aktivitet: kosthold, alkohol, tobakk, narkotika, skjermbaserte aktiviteter slik som tv, pc og spill. Det vanligste tiltaket var informasjonskampanjer i massemedia, i lokalmiljøet, i skolen eller på arbeidsplassen. Andre komponenter av tiltakene inkluderer endret struktur eller organisasjon for å tilrettelegge for fysisk aktivitet ved for eksempel å organisere fysisk aktivitet, opprette gangstier, gi tilgang til sportsutstyr eller sunnere mat. Atter andre endret lover og regler ved for eksempel røykeforbud på arbeidsplassen. Vi inkluderte totalt 79 sammenlikninger (basert på 75 studier) fra 22 land, som besvarte to problemstillinger. 78 sammenlikninger så på effekter av befolkningsrettede tiltak for å fremme fysisk aktivitet og endring i &eacute;n eller flere andre levevaner sammenliknet med ingen tiltak. Resultatene viser at befolkningsrettede opplysnings- og motivasjonstiltak: &bull; økte alle former for fysisk aktivitet i løpet av seks måneder, men det var ikke mulig å påvise effekt utover seks måneder &bull; det er usikkert om kaloriinntak ble endret i løpet av seks måneder. Kaloriinntaket ble redusert i løpet av ett til to år, men det var ikke mulig å påvise effekt ved lengre tids oppfølging &bull; økte inntak av både frukt og grønnsaker i løpet av seks måneder, men det var ikke mulig å påvise effekt utover seks måneder &bull; skjermbaserte aktiviteter ble litt redusert opp til ett år etter tiltaket, , men det var ikke mulig å påvise effekt ved lengre tids oppfølging &bull; økte mestring av kosthold alene og i kombinasjon med fysisk aktivitet i løpet av seks måneder, men ikke for mestring av fysisk aktivitet alene Det er usikkert om kroppsmasseindeks, røyking eller inntak av alkohol påvirkes. &Eacute;n sammenlikning så på effekter av et befolkningsrettet tiltak for økt fysisk aktivitet sammenliknet med et befolkningsrettet tiltak for bedret kosthold. Resultatene viser at det ikke var mulig å påvise effekt når det gjaldt fysisk aktivitet eller kroppsmasseindeks i løpet av ett år, og at det er uvisst om noen av tiltakene påvirket mestring og kosthold. 

**Diskusjon** 
Det at de fleste tiltakene var komplekse, tilsier at det er utfordringer å designe, innføre og evaluere effekten av dem. Det faktum at vi fant 59 randomiserte forsøk, viser at det er mulig å gjøre dette på en god måte. Tolkning av komplekse tiltak kan være vanskelig, og her var det svært komplekse tiltak. At så mange forskjellige tiltak gitt i så forskjellige settinger og kombinasjoner finner liknende resultater, bidrar derimot til å styrke tiltroen til konklusjonene. Styrken ved denne rapporten er at vi har brukt systematiske, eksplisitte og transparente kriterier for å finne, inkludere og vurdere kvaliteten av de inkluderte studiene. Utfordringer vi har hatt i dette arbeidet har vært å identifisere og sortere all relevant litteratur. Dette skyldtes mange publikasjon per enkelt studie (og sammenlikning), samme data publisert flere steder, samt at mange av studiene vi fant hadde mangelfull rapportering av metode, analyse og resultater. 

**Konklusjon** 
Befolkningsrettede opplysnings- og motivasjonstiltak for fysisk aktivitet i kombinasjon med &eacute;n eller flere andre levevaner, gir ved korttidsoppfølging flere viktige fordeler, men som ved langtidsoppfølging er færre. Denne rapporten bør leses i lys av at litteratursøket er to år gammelt. Det oppfordres til oppdatering, og vi foreslår at en eventuell nyere versjon kan begrenses til randomiserte kontrollerte studier.
AU  - Dahlgren,
AU  - A.
AU  - Lidal,
AU  - I.
AU  - B.
AU  - Mosdøl,
AU  - A.
AU  - Odgaard-Jensen,
AU  - J.
AU  - Denison,
AU  - E.
AU  - Vist,
AU  - G.
AU  - E.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - C:/Users/khorseng/Downloads/rapport_2015_09_befolkningsrettede-tiltak_v2.pdf
PY  - 2015
T2  - Folkehelseinstituttet
TI  - Effekter av befolkningsrettede opplysnings- og motivasjonstiltak for å fremme fysisk aktivitet og &eacute;n eller flere andre sunne levevaner
ER  -
TY  - JOUR
AB  - **Background:** 
There is evidence that family and friends influence children&#039;s decisions to smoke.

**Objectives:** 
To assess the effectiveness of interventions to help families stop children starting smoking.

**Search methods:** 
We searched 14 electronic bibliographic databases, including the Cochrane Tobacco Addiction Group specialized register, MEDLINE, EMBASE, PsycINFO, CINAHL unpublished material, and key articles&#039; reference lists. We performed free-text internet searches and targeted searches of appropriate websites, and hand-searched key journals not available electronically. We consulted authors and experts in the field. The most recent search was 3 April 2014. There were no date or language limitations.

**Selection criteria:** 
Randomised controlled trials (RCTs) of interventions with children (aged 5-12) or adolescents (aged 13-18) and families to deter tobacco use. The primary outcome was the effect of the intervention on the smoking status of children who reported no use of tobacco at baseline. Included trials had to report outcomes measured at least six months from the start of the intervention.

**Data collection and analysis:** 
We reviewed all potentially relevant citations and retrieved the full text to determine whether the study was an RCT and matched our inclusion criteria. Two authors independently extracted study data for each RCT and assessed them for risk of bias. We pooled risk ratios using a Mantel-Haenszel fixed effect model.

**Main results:** 
Twenty-seven RCTs were included. The interventions were very heterogeneous in the components of the family intervention, the other risk behaviours targeted alongside tobacco, the age of children at baseline and the length of follow-up. Two interventions were tested by two RCTs, one was tested by three RCTs and the remaining 20 distinct interventions were tested only by one RCT. Twenty-three interventions were tested in the USA, two in Europe, one in Australia and one in India.The control conditions fell into two main groups: no intervention or usual care; or school-based interventions provided to all participants. These two groups of studies were considered separately. Most studies had a judgement of &#039;unclear&#039; for at least one risk of bias criteria, so the quality of evidence was downgraded to moderate. Although there was heterogeneity between studies there was little evidence of statistical heterogeneity in the results. We were unable to extract data from all studies in a format that allowed inclusion in a meta-analysis.There was moderate quality evidence family-based interventions had a positive impact on preventing smoking when compared to a no intervention control. Nine studies (4810 participants) reporting smoking uptake amongst baseline non-smokers could be pooled, but eight studies with about 5000 participants could not be pooled because of insufficient data. The pooled estimate detected a significant reduction in smoking behaviour in the intervention arms (risk ratio [RR] 0.76, 95% confidence interval [CI] 0.68 to 0.84). Most of these studies used intensive interventions. Estimates for the medium and low intensity subgroups were similar but confidence intervals were wide. Two studies in which some of the 4487 participants already had smoking experience at baseline did not detect evidence of effect (RR 1.04, 95% CI 0.93 to 1.17).Eight RCTs compared a combined family plus school intervention to a school intervention only. Of the three studies with data, two RCTS with outcomes for 2301 baseline never smokers detected evidence of an effect (RR 0.85, 95% CI 0.75 to 0.96) and one study with data for 1096 participants not restricted to never users at baseline also detected a benefit (RR 0.60, 95% CI 0.38 to 0.94). The other five studies with about 18,500 participants did not report data in a format allowing meta-analysis. One RCT also compared a family intervention to a school &#039;good behaviour&#039; intervention and did not detect a difference between the two types of programme (RR 1.05, 95% CI 0.80 to 1.38, n = 388).No studies identified any adverse effects of intervention.

**Authors&#039; conclusions:** 
There is moderate quality evidence to suggest that family-based interventions can have a positive effect on preventing children and adolescents from starting to smoke. There were more studies of high intensity programmes compared to a control group receiving no intervention, than there were for other compairsons. The evidence is therefore strongest for high intensity programmes used independently of school interventions. Programmes typically addressed family functioning, and were introduced when children were between 11 and 14 years old. Based on this moderate quality evidence a family intervention might reduce uptake or experimentation with smoking by between 16 and 32%. However, these findings should be interpreted cautiously because effect estimates could not include data from all studies. Our interpretation is that the common feature of the effective high intensity interventions was encouraging authoritative parenting (which is usually defined as showing strong interest in and care for the adolescent, often with rule setting). This is different from authoritarian parenting (do as I say) or neglectful or unsupervised parenting.
AN  - CD004493
AU  - Thomas,
AU  - R.
AU  - E.
AU  - Baker,
AU  - P.
AU  - R.
AU  - Thomas,
AU  - B.
AU  - C.
AU  - Lorenzetti,
AU  - D.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004493
KW  - Family
KW  - Randomized Controlled Trials as Topic
KW  - Smoking [prevention &amp; control] [psychology]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Tobacco
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Family-based programmes for preventing smoking by children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004493.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004493.pub3/asset/CD004493.pdf?v=1&amp;t=iw7jgsxq&amp;s=5227ec4d4c92514a2f594f6eda2694349de3abea
ER  -
TY  - JOUR
AB  - **Aims**
To measure the effectiveness of antidepressants for adolescents and young adults with co-occurring depression and substance use disorder. 

**Design, Setting and Participants**
Meta-analysis of randomized controlled clinical trials. A comprehensive literature search of PubMed, Cochrane, Embase, Web of Science and PsychINFO was conducted (from 1970 to 2013). Prospective, parallel groups, double-blind, controlled trials with random assignment to an antidepressant or placebo on young patients (age 25 years) who met diagnostic criteria of both substance use and unipolar depressive disorder were included. Five trials were selected for this analysis and included 290 patients. 

**Measurements**
Our efficacy outcome measures were depression outcomes (dichotomous and continuous measures) and substance-use outcomes (change of frequency or quantity of substance-use). Secondary analysis was conducted to access the tolerability of antidepressant treatment. 

**Findings**
For dichotomous depression outcome, antidepressants group was significantly more effective than placebo group [risk ratio (RR)=1.21; 95% confidence interval (CI) 1.01-1.45], with low heterogeneity (I-2=0%). Although no statistically significant effects for continuous depression outcome [standardized mean differences (SMD)=-0.13; 95% CI, -0.55 to 0.30] were found with moderate heterogeneity (I-2=63%), subgroup analysis showed that the medicine group with a sample size of more than 50 showed statistically significant efficacy compared with the placebo group (SMD -0.53, 95% CI -0.82 to -0.25). Moreover, there was no significant difference for substance-use outcomes and tolerability outcomes between the medication and placebo groups. 

**Conclusions**
Antidepressant medication has a small overall effect in reducing depression in young patients with combined depressive and substance-use disorders, but does not appear to improve substance use outcomes.
AD  - [Zhou, Xinyu; Qin, Bin; Pan, Junxi; Liu, Yiyun; Yu, Jia; Xie, Peng] Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, Chongqing 400016, Peoples R China. [Del Giovane, Cinzia] Univ Modena &amp; Reggio Emilia, Dept Clin &amp; Diagnost Med, Modena, Italy. [Del Giovane, Cinzia] Univ Modena &amp; Reggio Emilia, Publ Hlth Italian Cochrane Ctr, Modena, Italy. [Gentile, Salvatore] ASL Salerno Mental Hlth Ctr, Dept Mental Hlth, Salerno, Italy. [Lan, Xinghui] Chongqing Med Univ, Childrens Hosp, Dept Neurol, Chongqing, Peoples R China. Xie, P (reprint author), Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China. xiepeng973@126.com
AN  - WOS:000346699700009
AU  - Zhou,
AU  - X.
AU  - Qin,
AU  - B.
AU  - Del
AU  - Giovane,
AU  - C.
AU  - Pan,
AU  - J.
AU  - Gentile,
AU  - S.
AU  - Liu,
AU  - Y.
AU  - Lan,
AU  - X.
AU  - Yu,
AU  - J.
AU  - Xie,
AU  - P.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
J2  - Addiction
KW  - adolescents
KW  - antidepressants
KW  - major depressive disorder
KW  - meta-analysis
KW  - substance use disorders
KW  - systematic review
KW  - cognitive-behavioral therapy
KW  - small sample-size
KW  - randomized
KW  - controlled-trial
KW  - placebo-controlled trial
KW  - double-blind
KW  - alcohol-use
KW  - comorbid depression
KW  - major depression
KW  - fluoxetine
KW  - dependence
KW  - Substance Abuse
KW  - Psychiatry
L1  - internal-pdf://1596784519/Zhou-2015-Efficacy and tolerability of antidep.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AX1IA Times Cited: 7 Cited Reference Count: 53 Zhou, Xinyu Qin, Bin Del Giovane, Cinzia Pan, Junxi Gentile, Salvatore Liu, Yiyun Lan, Xinghui Yu, Jia Xie, Peng Gentile, Salvatore/0000-0002-8303-725X National Basic Research Program of China (973 Program) [2009CB918300]; Natural Science Foundation Project of China (CSTC) [31271189] The study was funded by the National Basic Research Program of China (973 Program, Grant No. 2009CB918300) and Natural Science Foundation Project of China (CSTC, 31271189). The authors thank Anne-Liis von Knorring and Kurt Michael for their comments on an early draft of the manuscript. 7 0 22 Wiley-blackwell Hoboken 1360-0443
PY  - 2015
SP  - 38-48
T2  - Addiction
TI  - Efficacy and tolerability of antidepressants in the treatment of adolescents and young adults with depression and substance use disorders: a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000346699700009
UR  - http://onlinelibrary.wiley.com/doi/10.1111/add.12698/full
UR  - http://onlinelibrary.wiley.com/store/10.1111/add.12698/asset/add12698.pdf?v=1&amp;t=j02jld7j&amp;s=d79a23ebdea37ccdaa4f0a96d3d086134b57c5d7
VL  - 110
ER  -
TY  - JOUR
AB  - **BACKGROUND AND AIMS: **
Brief alcohol interventions in medical settings are efficacious in improving self-reported alcohol consumption among those with low-severity alcohol problems. Screening, Brief Intervention and Referral to Treatment initiatives presume that brief interventions are efficacious in linking patients to higher levels of care, but pertinent evidence has not been evaluated. We estimated main and subgroup effects of brief alcohol interventions, regardless of their inclusion of a referral-specific component, in increasing the utilization of alcohol-related care. 

**METHODS: **
A systematic review of English language papers published in electronic databases to 2013. We included randomized controlled trials (RCTs) of brief alcohol interventions in general health-care settings with adult and adolescent samples. We excluded studies that lacked alcohol services utilization data. Extractions of study characteristics and outcomes were standardized and conducted independently. The primary outcome was post-treatment alcohol services utilization assessed by self-report or administrative data, which we compared across intervention and control groups.

**RESULTS: **
Thirteen RCTs met inclusion criteria and nine were meta-analyzed (n=993 and n=937 intervention and control group participants, respectively). In our main analyses the pooled risk ratio (RR) was=1.08, 95% confidence interval (CI)=0.92-1.28. Five studies compared referral-specific interventions with a control condition without such interventions (pooled RR=1.08, 95% CI=0.81-1.43). Other subgroup analyses of studies with common characteristics (e.g. age, setting, severity, risk of bias) yielded non-statistically significant results. 

**CONCLUSIONS: **
There is a lack of evidence that brief alcohol interventions have any efficacy for increasing the receipt of alcohol-related services. 

Copyright &copy; 2015 Society for the Study of Addiction.
AD  - Glass, Joseph E. School of Social Work, University of Wisconsin-Madison, Madison, WI, USA. Hamilton, Ashley M. Chrysalis, Inc., Madison, WI, USA. Powell, Byron J. Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Perron, Brian E. School of Social Work, University of Michigan, Ann Arbor, MI, USA. Brown, Randall T. Department of Family Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA. Ilgen, Mark A. VA Center for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System and the Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.
AN  - 25913697
AU  - Glass,
AU  - J.
AU  - E.
AU  - Hamilton,
AU  - A.
AU  - M.
AU  - Powell,
AU  - B.
AU  - J.
AU  - Perron,
AU  - B.
AU  - E.
AU  - Brown,
AU  - R.
AU  - T.
AU  - Ilgen,
AU  - M.
AU  - A.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/add.12950
DP  - Ovid Technologies
J2  - Addiction
KW  - *Alcohol-Related Disorders/th [Therapy]
KW  - Counseling/mt [Methods]
KW  - *Counseling/sn [Statistics &amp; Numerical Data]
KW  - Humans
KW  - *Randomized Controlled Trials as Topic
KW  - *Referral and Consultation/sn [Statistics &amp; Numerical Data]
KW  - Substance-Related Disorders/th [Therapy]
L1  - internal-pdf://0693825968/Glass-2015-Specialty substance use disorder se.pdf
LA  - English
M3  - Meta-Analysis
N1  - Glass, Joseph E Hamilton, Ashley M Powell, Byron J Perron, Brian E Brown, Randall T Ilgen, Mark A Comment in: Addiction. 2016 Jan;111(1):181-3; PMID: 26464318 Comment in: Addiction. 2016 Jan;111(1):180-1; PMID: 26464266
PY  - 2015
SP  - 1404-15
T2  - Addiction
TI  - Specialty substance use disorder services following brief alcohol intervention: a meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25913697http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25913697&amp;id=doi:10.1111%2Fadd.12950&amp;issn=0965-2140&amp;isbn=&amp;volume=110&amp;issue=9&amp;spage=1404&amp;pages=1404-15&amp;date=2015&amp;title=Addiction&amp;atitle=Specialty+substance+use+disorder+services+following+brief+alcohol+intervention%3A+a+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Glass&amp;pid=%3Cauthor%3EGlass+JE%3C%2Fauthor%3E%3CAN%3E25913697%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://deepblue.lib.umich.edu/bitstream/handle/2027.42/112279/add12950.pdf?sequence=1
VL  - 110
ER  -
TY  - JOUR
AB  - Youth antisocial behavior exacts a tremendous toll on society and often persists into adulthood. Although researchers have identified a number of psychosocial interventions that prevent or reduce youth antisocial behavior in the short term, evidence of long-term intervention benefits has only recently become available. 

In addition, research on such interventions spans two substantial but largely separate bodies of literature: prevention and therapy. The present study used meta-analysis to integrate research on the long-term effects of preventive and therapeutic interventions for youth antisocial behavior and examined potential moderators of these effects. 

Results from 66 intervention trials (i.e., 34 prevention, 32 therapy) indicated that a broad range of youth psychosocial interventions demonstrated modest effects on antisocial behavior (mean d=0.31, 95% confidence interval=0.23-0.39) for at least one year beyond the end of interventions relative to control conditions. 

Among other findings, moderator analyses revealed that inclusion of a peer group intervention component was associated with reduced intervention effects for samples consisting predominantly of boys or older youths. 

The results of this study have important implications for service providers, administrators, and policymakers involved in the implementation of preventive and therapeutic interventions targeting youth antisocial behavior. 

Copyright &copy; 2015 Elsevier Ltd. All rights reserved.
AD  - Sawyer, Aaron M. University of Missouri, Department of Psychological Sciences, 210 McAlester Hall, Columbia, MO 65211, United States. Electronic address: sawyeraa@missouri.edu. Borduin, Charles M. University of Missouri, Department of Psychological Sciences, 210 McAlester Hall, Columbia, MO 65211, United States. Dopp, Alex R. University of Missouri, Department of Psychological Sciences, 210 McAlester Hall, Columbia, MO 65211, United States.
AN  - 26197725
AU  - Sawyer,
AU  - A.
AU  - M.
AU  - Borduin,
AU  - C.
AU  - M.
AU  - Dopp,
AU  - A.
AU  - R.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cpr.2015.06.009
DP  - Ovid Technologies
J2  - Clin Psychol Rev
KW  - Adolescent
KW  - *Adolescent Behavior/px [Psychology]
KW  - *Behavior Therapy/mt [Methods]
KW  - Child
KW  - Child, Preschool
KW  - Female
KW  - Humans
KW  - Infant
KW  - Male
KW  - *Outcome Assessment (Health Care)
KW  - *Peer Group
KW  - Social Behavior Disorders/pc [Prevention &amp; Control]
KW  - *Social Behavior Disorders/th [Therapy]
L1  - internal-pdf://3783242930/Sawyer-2015-Long-term effects of prevention an.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Sawyer, Aaron M Borduin, Charles M Dopp, Alex R S0272-7358(15)00099-9
PY  - 2015
SP  - 130-44
T2  - Clinical Psychology Review
TI  - Long-term effects of prevention and treatment on youth antisocial behavior: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26197725http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26197725&amp;id=doi:10.1016%2Fj.cpr.2015.06.009&amp;issn=0272-7358&amp;isbn=&amp;volume=42&amp;issue=&amp;spage=130&amp;pages=130-44&amp;date=2015&amp;title=Clinical+Psychology+Review&amp;atitle=Long-term+effects+of+prevention+and+treatment+on+youth+antisocial+behavior%3A+A+meta-analysis.&amp;aulast=Sawyer&amp;pid=%3Cauthor%3ESawyer+AM%3C%2Fauthor%3E%3CAN%3E26197725%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0272735815000999/1-s2.0-S0272735815000999-main.pdf?_tid=59538a70-04cf-11e7-93d6-00000aacb362&amp;acdnat=1489067606_7d7350537a630ecbbb512f991afb1cfc
VL  - 42
ER  -
TY  - JOUR
AB  - Although several meta-analyses have investigated the efficacy of psychological treatments for pediatric obsessive-compulsive disorder (OCD), there is not yet a consensus on the most efficacious treatment components. 

A meta-analysis was carried out to examine the efficacy of the different treatment techniques used in the psychological interventions of pediatric OCD. An exhaustive literature search from 1983 to February 2014 enabled us to locate 46 published articles that applied some kind of cognitive-behavioral therapy (CBT). 

For each group the effect size was the standardized pretest-posttest mean change, and it was calculated for obsessive-compulsive symptoms and for other outcome measures. The results clearly showed large effect sizes for CBT in reducing obsessive-compulsive symptoms and, to a lesser extent, other outcome measures (d + = 1.860; 95% CI: 1.639; 2.081). 

The most promising treatments are those based on multicomponent programs comprising ERP, cognitive strategies, and relapse prevention. The analysis of other potential moderator variables and the implications for clinical practice are discussed.
AD  - Rosa-Alcazar, Ana I. Universidad de Murcia (Spain). Sanchez-Meca, Julio. Universidad de Murcia (Spain). Rosa-Alcazar, Angel. Universidad de Murcia (Spain). Iniesta-Sepulveda, Marina. Universidad de Murcia (Spain). Olivares-Rodriguez, Jose. Universidad de Murcia (Spain). Parada-Navas, Jose L. Universidad de Murcia (Spain).
AN  - 25901842
AU  - Rosa-Alcazar,
AU  - A.
AU  - I.
AU  - Sanchez-Meca,
AU  - J.
AU  - Rosa-Alcazar,
AU  - A.
AU  - Iniesta-Sepulveda,
AU  - M.
AU  - Olivares-Rodriguez,
AU  - J.
AU  - Parada-Navas,
AU  - J.
AU  - L.
DA  - Apr 22
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1017/sjp.2015.22
DP  - Ovid Technologies
J2  - Span J Psychol
KW  - Adolescent
KW  - Child
KW  - *Cognitive Therapy/mt [Methods]
KW  - Humans
KW  - *Obsessive-Compulsive Disorder/th [Therapy]
KW  - *Outcome Assessment (Health Care)
L1  - internal-pdf://1412017956/div-class-title-psychological-treatment-of-obs.pdf
LA  - English
M3  - Meta-Analysis
N1  - Rosa-Alcazar, Ana I Sanchez-Meca, Julio Rosa-Alcazar, Angel Iniesta-Sepulveda, Marina Olivares-Rodriguez, Jose Parada-Navas, Jose L S1138741615000220
PY  - 2015
SP  - E20
T2  - Spanish Journal of Psychology
TI  - Psychological treatment of obsessive-compulsive disorder in children and adolescents: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25901842http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25901842&amp;id=doi:10.1017%2Fsjp.2015.22&amp;issn=1138-7416&amp;isbn=&amp;volume=18&amp;issue=&amp;spage=E20&amp;pages=E20&amp;date=2015&amp;title=Spanish+Journal+of+Psychology&amp;atitle=Psychological+treatment+of+obsessive-compulsive+disorder+in+children+and+adolescents%3A+a+meta-analysis.&amp;aulast=Rosa-Alcazar&amp;pid=%3Cauthor%3ERosa-Alcazar+AI%3C%2Fauthor%3E%3CAN%3E25901842%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 18
ER  -
TY  - JOUR
AB  - In recent years, acupuncture has increasingly being integrated into pediatric health care. It was used on ~150,000 children (0.2%). We aim to update the evidence for the efficacy and safety of acupuncture for children and evaluate the methodological qualities of these studies to improve future research in this area. 

We included 24 systematic reviews, comprising 142 randomized controlled trials (RCTs) with 12,787 participants. Only 25% (6/24) reviews were considered to be high quality (10.00+/-0.63). High-quality systematic reviews and Cochrane systematic reviews tend to yield neutral or negative results (P = 0.052, 0.009 respectively). The efficacy of acupuncture for five diseases (Cerebral Palsy (CP), nocturnal enuresis, tic disorders, amblyopia, and pain reduction) is promising. 

It was unclear for hypoxic ischemic encephalopathy, attention deficit hyperactivity disorder, mumps, autism spectrum disorder (ASD), asthma, nausea/vomiting, and myopia. Acupuncture is not effective for epilepsy. Only six reviews reported adverse events (AEs) and no fatal side effects were reported. The efficacy of acupuncture for some diseases is promising and there have been no fatal side effects reported. 

Further high-quality studies are justified, with five diseases in particular as research priorities.
AD  - Yang, Chunsong. Department of Pharmacy, Evidence-based Pharmacy Center, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. Hao, Zilong. Department of Neurology, West China Hospital, Sichuan University, Chengdu, China. Zhang, Ling-Li. Department of Pharmacy, Evidence-based Pharmacy Center, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. Guo, Qin. Department of Pediatrics, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China.
AN  - 25950453
AU  - Yang,
AU  - C.
AU  - Hao,
AU  - Z.
AU  - Zhang,
AU  - L.
AU  - L.
AU  - Guo,
AU  - Q.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1038/pr.2015.91
DP  - Ovid Technologies
J2  - Pediatr Res
KW  - *Acupuncture Therapy/ae [Adverse Effects]
KW  - *Acupuncture Therapy/st [Standards]
KW  - Child
KW  - Humans
KW  - Patient Safety
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://4087411616/Yang-2015-Efficacy and safety of acupuncture i.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Yang, Chunsong Hao, Zilong Zhang, Ling-Li Guo, Qin pr201591
PY  - 2015
SP  - 112-9
T2  - Pediatric Research
TI  - Efficacy and safety of acupuncture in children: an overview of systematic reviews
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25950453http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25950453&amp;id=doi:10.1038%2Fpr.2015.91&amp;issn=0031-3998&amp;isbn=&amp;volume=78&amp;issue=2&amp;spage=112&amp;pages=112-9&amp;date=2015&amp;title=Pediatric+Research&amp;atitle=Efficacy+and+safety+of+acupuncture+in+children%3A+an+overview+of+systematic+reviews.&amp;aulast=Yang&amp;pid=%3Cauthor%3EYang+C%3C%2Fauthor%3E%3CAN%3E25950453%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://www.nature.com/pr/journal/v78/n2/pdf/pr201591a.pdf
VL  - 78
ER  -
TY  - JOUR
AB  - **Slutsatser**
Det finns två skolbaserade program som m&ouml;jligen kan f&ouml;rebygga suicidf&ouml;rs&ouml;k. Dessa &auml;r dock inte testade på ett vetenskapligt s&auml;tt i Sverige. Båda de program som har visat effekt &auml;r universella, det vill s&auml;ga riktas till alla elever i klasserna.- Good Behavior Game (GBG) ges på lågstadiet under ett till två år. GBG &auml;r inte utvecklat f&ouml;r att f&ouml;rebygga sj&auml;lvskada utan syftar till att f&ouml;rst&auml;rka positiva beteenden och attityder mellan skolelever och l&auml;rare.- Youth Aware of Mental Health (YAM) ges på h&ouml;gstadiet och består huvudsakligen av fem timmars interaktiva &ouml;vningar. YAM &auml;r utvecklat specifikt f&ouml;r att f&ouml;rebygga suicid.

F&ouml;r &ouml;vriga program saknas tillr&auml;ckligt underlag f&ouml;r att dra slutsatser om effekt på suicidf&ouml;rs&ouml;k.

Studier av program som f&ouml;rebygger andra former av sj&auml;lvskadebeteende har enbart unders&ouml;kt effekter på attityder eller har saknat uppf&ouml;ljningstid.Det går inte att dra några slutsatser om eventuella negativa effekter av de skolbaserade programmen eftersom det finns få studier på området.
AU  - Statens
AU  - beredning
AU  - f&ouml;r
AU  - medicinsk
AU  - och
AU  - social
AU  - utv&auml;rdering
AU  - (SBU)
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /sv/publikationer/SBU-utvarderar/skolbaserade-program-for-att-forebygga-sjalvskadebeteende-inklusive-suicidforsok/
L1  - internal-pdf://2617425324/skolbaserade_program_forebygga_sjalvskadebetee.pdf
PY  - 2015
TI  - Skolbaserade program f&ouml;r att f&ouml;rebygga sj&auml;lvskadebeteende inklusive suicidf&ouml;rs&ouml;k. En systematisk litteratur&ouml;versikt.
ER  -
TY  - JOUR
AB  - Serotonin reuptake inhibiting drugs (SRI) have been used in the treatment of paediatric obsessive-compulsive disorder over the past 30 years. We performed a systematic review and meta-analysis of the literature to discuss the place of and evidence for the use of SRI in paediatric OCD, based on 14 publications of methodologically sound, randomized and controlled studies. 

Both SRI and specific SRIs were examined and comparisons of SRI, placebo, cognitive behaviour therapy (CBT), combined (COMBO) treatments (SRI+CBT) made to investigate their relative efficacy. Using the Cochrane methodology, and as measures of effect size mean difference and Hedge&#039;s g, SRIs proved to be superior to drug placebo, with a modest effect size. 

From direct comparisons of CBT and SRI treatments, we conclude that CBT has the superior efficacy. COMBO versus CBT shows that SRI treatment adds little to concomitant CBT, while COMBO shows favourable outcome versus SRI alone. 

In pre-trial partial treatment responders, those who failed a SRI had better outcome from adding CBT as compared to continuing a SRI. Those who failed CBT treatment did as well with continued CBT as with switching to a SRI. The studies of combinations and sequences of treatments need to be developed further. 

Copyright &copy; 2015 Elsevier Ireland Ltd. All rights reserved.
AD  - Ivarsson, Tord. Center for Child and Adolescent Mental Health, Eastern and Southern Norway, Postboks 4623 Nydalen, 0405 Oslo, Norway. Electronic address: tord.ivarsson@r-bup.no. Skarphedinsson, Gudmundur. Center for Child and Adolescent Mental Health, Eastern and Southern Norway, Postboks 4623 Nydalen, 0405 Oslo, Norway. Kornor, Hege. Center for Child and Adolescent Mental Health, Eastern and Southern Norway, Postboks 4623 Nydalen, 0405 Oslo, Norway. Axelsdottir, Brynhildur. Center for Child and Adolescent Mental Health, Eastern and Southern Norway, Postboks 4623 Nydalen, 0405 Oslo, Norway. Biedilae, Solvi. Center for Child and Adolescent Mental Health, Eastern and Southern Norway, Postboks 4623 Nydalen, 0405 Oslo, Norway. Heyman, Isobel. Department of Child and Adolescent Mental Health, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK. Asbahr, Fernando. Child and Adolescent Anxiety Disorders Program, Department of Psychiatry University of Sao Paulo Medical School, Brazil. Thomsen, Per Hove. Aarhus University Hospital, Child and Adolescent Psychiatric Centre, Risskov, Denmark. Fineberg, Naomi. National Obsessive Compulsive Disorders Specialist Service, Hertfordshire Partnership NHS Foundation Trust, Queen Elizabeth II Hospital, Welwyn Garden City, Herts, UK. March, John. Duke University Medical Center, Durham, NC, USA.
AN  - 25769521
AU  - Ivarsson,
AU  - T.
AU  - Skarphedinsson,
AU  - G.
AU  - Kornor,
AU  - H.
AU  - Axelsdottir,
AU  - B.
AU  - Biedilae,
AU  - S.
AU  - Heyman,
AU  - I.
AU  - Asbahr,
AU  - F.
AU  - Thomsen,
AU  - P.
AU  - H.
AU  - Fineberg,
AU  - N.
AU  - March,
AU  - J.
AU  - Accreditation
AU  - Task
AU  - Force
AU  - of
AU  - The
AU  - Canadian
AU  - Institute
AU  - for
AU  - Obsessive
AU  - Compulsive
AU  - Disorders
DA  - May 30
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - http://dx.doi.org/10.1016/j.psychres.2015.01.015
DP  - Ovid Technologies
J2  - Psychiatry Res
KW  - Adolescent
KW  - Child
KW  - *Cognitive Therapy/mt [Methods]
KW  - Combined Modality Therapy
KW  - Humans
KW  - Obsessive-Compulsive Disorder/dt [Drug Therapy]
KW  - Obsessive-Compulsive Disorder/px [Psychology]
KW  - *Obsessive-Compulsive Disorder/th [Therapy]
KW  - *Serotonin Uptake Inhibitors/tu [Therapeutic Use]
KW  - Treatment Outcome
KW  - 0 (Serotonin Uptake Inhibitors)
L1  - internal-pdf://1991906708/Ivarsson-2015-The place of and evidence for se.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Ivarsson, Tord Skarphedinsson, Gudmundur Kornor, Hege Axelsdottir, Brynhildur Biedilae, Solvi Heyman, Isobel Asbahr, Fernando Thomsen, Per Hove Fineberg, Naomi March, John Accreditation Task Force of The Canadian Institute for Obsessive Compulsive Disorders S0165-1781(15)00053-0
PY  - 2015
SP  - 93-103
T2  - Psychiatry Research
TI  - The place of and evidence for serotonin reuptake inhibitors (SRIs) for obsessive compulsive disorder (OCD) in children and adolescents: Views based on a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25769521http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25769521&amp;id=doi:10.1016%2Fj.psychres.2015.01.015&amp;issn=0165-1781&amp;isbn=&amp;volume=227&amp;issue=1&amp;spage=93&amp;pages=93-103&amp;date=2015&amp;title=Psychiatry+Research&amp;atitle=The+place+of+and+evidence+for+serotonin+reuptake+inhibitors+%28SRIs%29+for+obsessive+compulsive+disorder+%28OCD%29+in+children+and+adolescents%3A+Views+based+on+a+systematic+review+and+meta-analysis.&amp;aulast=Ivarsson&amp;pid=%3Cauthor%3EIvarsson+T%3C%2Fauthor%3E%3CAN%3E25769521%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0165178115000530/1-s2.0-S0165178115000530-main.pdf?_tid=fa132102-04c8-11e7-8852-00000aacb362&amp;acdnat=1489064869_a77257b742212a873692b528bc260dfc
VL  - 227
ER  -
TY  - JOUR
AB  - **OBJECTIVE:**
Although psychostimulants are commonly utilized to treat preschoolers with ADHD, side effects and parental preferences limit their use in younger children. The current meta-analysis examines the efficacy of parent interventions for the treatment of ADHD in preschoolers. 

**METHOD:**
We searched PubMed and the Cochrane Library for randomized, controlled trials comparing behavioral interventions for preschool children with ADHD. Our primary outcome measure was mean improvement in an ADHD rating scale compared with control conditions. 

**RESULTS: **
Eight trials were included in the final analysis, totaling 399 participants. There was a significant benefit of parental behavioral interventions compared with control conditions (standardized mean difference [SMD] = 0.61, 95% confidence interval = [0.40, 0.83], z = 5.6, p &lt; .001). 

**CONCLUSION: **
The present meta-analysis provides preliminary evidence that parental interventions are an efficacious treatment for preschool ADHD. Future research is needed to compare the relative efficacy of parental interventions for ADHD with medication management and to determine if the combination of parental training and medication management is more effective than either condition alone.

Copyright &copy; 2013 SAGE Publications.
AD  - Mulqueen,Jilian M. Yale University School of Medicine, New Haven, CT, USA. Bartley,Christine A. Yale University School of Medicine, New Haven, CT, USA. Bloch,Michael H. Yale University School of Medicine, New Haven, CT, USA michael.bloch@yale.edu.
AN  - 24071773
AU  - Mulqueen,
AU  - J.
AU  - M.
AU  - Bartley,
AU  - C.
AU  - A.
AU  - Bloch,
AU  - M.
AU  - H.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1087054713504135
DP  - Ovid Technologies
J2  - J Atten Disord
LA  - English
M3  - Research Support, N.I.H., Extramural
N1  - Mulqueen, Jilian M Bartley, Christine A Bloch, Michael H 1K23MH091240 (United States NIMH NIH HHS) UL1RR024139 (United States NCRR NIH HHS)
PY  - 2015
SP  - 118-24
T2  - Journal of Attention Disorders
TI  - Meta-analysis: parental interventions for preschool ADHD
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24071773 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24071773&amp;id=doi:10.1177%2F1087054713504135&amp;issn=1087-0547&amp;isbn=&amp;volume=19&amp;issue=2&amp;spage=118&amp;pages=118-24&amp;date=2015&amp;title=Journal+of+Attention+Disorders&amp;atitle=Meta-analysis%3A+parental+interventions+for+preschool+ADHD.&amp;aulast=Mulqueen&amp;pid=%3Cauthor%3EMulqueen+JM%3C%2Fauthor%3E%3CAN%3E24071773%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://jad.sagepub.com/content/19/2/118http://jad.sagepub.com/content/19/2/118.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/1087054713504135?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 19
ER  -
TY  - JOUR
AB  - Postnatal depression (PND) has negative effects on maternal well-being as well as implications for the mother-infant relationship, subsequent infant development, and family functioning. 

There is growing evidence demonstrating that PND impacts on a mother&#039;s ability to interact with sensitivity and responsiveness as a caregiver, which may have implications for the infant&#039;s development of self-regulatory skills, making the infant more vulnerable to later psychopathology. Given the possible intergenerational transmission of risk to the infant, the mother-infant relationship is a focus for treatment and research. 

However, few studies have assessed the effect of treatment on the mother-infant relationship and child developmental outcomes. The main aim of this paper was to conduct a systematic review and investigate effect sizes of interventions for PND, which assess the quality of the mother-infant dyad relationship and/or child outcomes in addition to maternal mood. 

Nineteen studies were selected for review, and their methodological quality was evaluated, where possible, effect sizes across maternal mood, quality of dyadic relationship, and child developmental outcomes were calculated. Finally, clinical implications in the treatment of PND are highlighted and recommendations made for further research.
AD  - Tsivos, Zoe-Lydia. School of Psychological Sciences, University of Manchester, Manchester, UK. Calam, Rachel. School of Psychological Sciences, University of Manchester, Manchester, UK. Sanders, Matthew R. School of Psychological Sciences, University of Manchester, Manchester, UK ; Parenting and Family Support Center, University of Queensland, Brisbane, Australia. Wittkowski, Anja. School of Psychological Sciences, University of Manchester, Manchester, UK.
AN  - 25960678
AU  - Tsivos,
AU  - Z.
AU  - L.
AU  - Sanders,
AU  - M.
AU  - R.
AU  - Wittkowski,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2147/IJWH.S75311
DP  - Ovid Technologies
J2  - Int J Women Health
L1  - internal-pdf://0200792198/Tsivos-2015-Interventions for postnatal depres.pdf
LA  - English
M3  - Review
N1  - Tsivos, Zoe-Lydia Calam, Rachel Sanders, Matthew R Wittkowski, Anja ijwh-7-429
PY  - 2015
SP  - 429-47
T2  - International Journal of Women&#039;s Health
TI  - Interventions for postnatal depression assessing the mother-infant relationship and child developmental outcomes: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25960678http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25960678&amp;id=doi:10.2147%2FIJWH.S75311&amp;issn=1179-1411&amp;isbn=&amp;volume=7&amp;issue=&amp;spage=429&amp;pages=429-47&amp;date=2015&amp;title=International+Journal+of+Women%27s+Health&amp;atitle=Interventions+for+postnatal+depression+assessing+the+mother-infant+relationship+and+child+developmental+outcomes%3A+a+systematic+review.&amp;aulast=Tsivos&amp;pid=%3Cauthor%3ETsivos+ZL%3C%2Fauthor%3E%3CAN%3E25960678%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.dovepress.com/getfile.php?fileID=24771
VL  - 7
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Anxiety and depression in children and adolescents are undertreated. Computer- and Internet-based cognitive behavioral treatments (cCBT) may be an attractive treatment alternative to regular face-to-face treatment.This meta-analysis aims to evaluate whether cCBT is effective for treating symptoms of anxiety and depression in youth. 

**METHODS AND FINDINGS: **
We conducted systematic searches in bibliographical databases (Pubmed, Cochrane controlled trial register, PsychInfo) up to December 4, 2013. Only randomized controlled trials in which a computer-, Internet- or mobile-based cognitive behavioral intervention targeting either depression, anxiety or both in children or adolescents up to the age of 25 were compared to a control condition were selected. We employed a random-effects pooling model in overall effect analyses and a mixed effect model for sub-group analyses. Searches resulted in identifying 13 randomized trials, including 796 children and adolescents that met inclusion criteria. Seven studies were directed at treating anxiety, four studies at depression, and two were of a transdiagnostic nature, targeting both anxiety and depression. The overall mean effect size (Hedges&#039; g) of cCBT on symptoms of anxiety or depression at post-test was g=0.72 (95% CI:0.55-0.90, numbers needed to be treated (NNT)=2.56). Heterogeneity was low (I2=20.14%, 95% CI: 0-58%). The superiority of cCBT over controls was evident for interventions targeting anxiety (g=0.68; 95% CI: 0.45-0.92; p &lt; .001; NNT=2.70) and for interventions targeting depression (g=0.76; 95% CI: 0.41-0.12; p &lt; .001; NNT=2.44) as well as for transdiagnostic interventions (g=0.94; 95% CI: 0.23-2.66; p &lt; .001; NNT=2.60). 

**CONCLUSIONS: **
Results provide evidence for the efficacy of cCBT in the treatment of anxiety and depressive symptoms in youth. Hence, such interventions may be a promising treatment alternative when evidence based face-to-face treatment is not feasible. Future studies should examine long-term effects of treatments and should focus on obtaining patient-level data from existing studies, to perform an individual patient data meta-analysis.
AD  - Ebert,David Daniel. Leuphana University, Innovation Incubator, Division Health Trainings Online, Lueneburg, Germany; Friedrich-Alexander University Nuremberg-Erlangen, Department of Psychology, Clinical Psychology and Psychotherapy, Erlangen, Germany; Department of Clinical Psychology and EMGO Institute for Health and Care Research, VU University, Amsterdam, the Netherlands. Zarski,Anna-Carlotta. Leuphana University, Innovation Incubator, Division Health Trainings Online, Lueneburg, Germany. Christensen,Helen. Black Dog Institute, Sydney, Australia. Stikkelbroek,Yvonne. Center for Child and Adolescent Studies, University of Utrecht, the Netherlands. Cuijpers,Pim. Leuphana University, Innovation Incubator, Division Health Trainings Online, Lueneburg, Germany; GGZ inGeest, Regional Mental Health Service Centre, VU University Medical Centre, Amsterdam, the Netherlands; Department of Clinical Psychology and EMGO Institute for Health and Care Research, VU University, Amsterdam, the Netherlands. Berking,Matthias. Leuphana University, Innovation Incubator, Division Health Trainings Online, Lueneburg, Germany; Friedrich-Alexander University Nuremberg-Erlangen, Department of Psychology, Clinical Psychology and Psychotherapy, Erlangen, Germany. Riper,Heleen. Leuphana University, Innovation Incubator, Division Health Trainings Online, Lueneburg, Germany; GGZ inGeest, Regional Mental Health Service Centre, VU University Medical Centre, Amsterdam, the Netherlands; Department of Clinical Psychology and EMGO Institute for Health and Care Research, VU University, Amsterdam, the Netherlands.
AN  - 25786025
AU  - Ebert,
AU  - D.
AU  - D.
AU  - Zarski,
AU  - A.
AU  - C.
AU  - Christensen,
AU  - H.
AU  - Stikkelbroek,
AU  - Y.
AU  - Cuijpers,
AU  - P.
AU  - Berking,
AU  - M.
AU  - Riper,
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1371/journal.pone.0119895
DP  - Ovid Technologies
J2  - PLoS ONE
L1  - internal-pdf://3190487061/Ebert-2015-Internet and computer-based cogniti.pdf
LA  - English
N1  - Ebert, David Daniel Zarski, Anna-Carlotta Christensen, Helen Stikkelbroek, Yvonne Cuijpers, Pim Berking, Matthias Riper, Heleen
PY  - 2015
SP  - e0119895
T2  - PLoS ONE [Electronic Resource]
TI  - Internet and computer-based cognitive behavioral therapy for anxiety and depression in youth: a meta-analysis of randomized controlled outcome trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25786025 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25786025&amp;id=doi:10.1371%2Fjournal.pone.0119895&amp;issn=1932-6203&amp;isbn=&amp;volume=10&amp;issue=3&amp;spage=e0119895&amp;pages=e0119895&amp;date=2015&amp;title=PLoS+ONE+%5BElectronic+Resource%5D&amp;atitle=Internet+and+computer-based+cognitive+behavioral+therapy+for+anxiety+and+depression+in+youth%3A+a+meta-analysis+of+randomized+controlled+outcome+trials.&amp;aulast=Ebert&amp;pid=%3Cauthor%3EEbert+DD%3C%2Fauthor%3E%3CAN%3E25786025%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364968/pdf/pone.0119895.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364968/pdf/pone.0119895.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
Children with chronic physical illness are significantly more likely to develop common psychiatric symptoms than otherwise healthy children. These children therefore warrant effective integrated healthcare yet it is not established whether the known, effective, psychological treatments for symptoms of common childhood mental health disorders work in children with chronic physical illness.

**METHODS: **
EMBASE, MEDLINE, PsycINFO and CINAHL databases were searched with predefined terms relating to evidence-based psychological interventions for psychiatric symptoms in children with chronic physical illness. We included all studies (randomised and non-randomised designs) investigating interventions aimed primarily at treating common psychiatric symptoms in children with a chronic physical illness in the review. Two reviewers independently assessed the relevance of abstracts identified, extracted data and undertook quality analysis. 

**RESULTS: **
Ten studies (209 children, including 70 in control groups) met the criteria for inclusion in the review. All studies demonstrated some positive outcomes of cognitive behavioural therapy for the treatment of psychiatric symptoms in children with chronic physical illness. Only two randomised controlled trials, both investigating interventions for symptoms of depression, were found. 

**CONCLUSIONS: **
There is preliminary evidence that cognitive behavioural therapy has positive effects in the treatment of symptoms of depression and anxiety in children with chronic physical illness. However, the current evidence base is weak and fully powered randomised controlled trials are needed to establish the efficacy of psychological treatments in this vulnerable population. 

Copyright Published by the BMJ Publishing Group Limited.
AD  - Bennett, Sophie. UCL Institute of Child Health, University College London, London, UK. Shafran, Roz. UCL Institute of Child Health, University College London, London, UK. Coughtrey, Anna. Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. Walker, Susan. UCL Institute of Child Health, University College London, London, UK Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. Heyman, Isobel. UCL Institute of Child Health, University College London, London, UK Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
AN  - 25784736
AU  - Bennett,
AU  - S.
AU  - Shafran,
AU  - R.
AU  - Coughtrey,
AU  - A.
AU  - Walker,
AU  - S.
AU  - Heyman,
AU  - I.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/archdischild-2014-307474
DP  - Ovid Technologies
J2  - Arch Dis Child
KW  - *Anxiety Disorders/th [Therapy]
KW  - Child
KW  - *Chronic Disease/px [Psychology]
KW  - *Cognitive Therapy/mt [Methods]
KW  - *Depressive Disorder/th [Therapy]
KW  - Humans
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
L1  - internal-pdf://1179947954/Bennett-2015-Psychological interventions for m.pdf
LA  - English
M3  - Review
N1  - Bennett, Sophie Shafran, Roz Coughtrey, Anna Walker, Susan Heyman, Isobel Comment in: Arch Dis Child. 2015 Apr;100(4):303-4; PMID: 25784735 archdischild-2014-307474
PY  - 2015
SP  - 308-16
T2  - Archives of Disease in Childhood
TI  - Psychological interventions for mental health disorders in children with chronic physical illness: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25784736http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25784736&amp;id=doi:10.1136%2Farchdischild-2014-307474&amp;issn=0003-9888&amp;isbn=&amp;volume=100&amp;issue=4&amp;spage=308&amp;pages=308-16&amp;date=2015&amp;title=Archives+of+Disease+in+Childhood&amp;atitle=Psychological+interventions+for+mental+health+disorders+in+children+with+chronic+physical+illness%3A+a+systematic+review.&amp;aulast=Bennett&amp;pid=%3Cauthor%3EBennett+S%3C%2Fauthor%3E%3CAN%3E25784736%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://adc.bmj.com/content/archdischild/100/4/308.full.pdf
VL  - 100
ER  -
TY  - JOUR
AB  - **Background:** 
Child sexual abuse is a significant global problem in both magnitude and sequelae. The most widely used primary prevention strategy has been the provision of school-based education programmes. Although programmes have been taught in schools since the 1980s, their effectiveness requires ongoing scrutiny.

**Objectives:** 
To systematically assess evidence of the effectiveness of school-based education programmes for the prevention of child sexual abuse. Specifically, to assess whether: programmes are effective in improving students&#039; protective behaviours and knowledge about sexual abuse prevention; behaviours and skills are retained over time; and participation results in disclosures of sexual abuse, produces harms, or both.

**Search methods:** 
In September 2014, we searched CENTRAL, Ovid MEDLINE, EMBASE and 11 other databases. We also searched two trials registers and screened the reference lists of previous reviews for additional trials.Selection criteria: We selected randomised controlled trials (RCTs), cluster-RCTs, and quasi-RCTs of school-based education interventions for the prevention of child sexual abuse compared with another intervention or no intervention.

**Data collection and analysis:** 
Two review authors independently assessed the eligibility of trials for inclusion, extracted data, and assessed risk of bias. We summarised data for six outcomes: protective behaviours; knowledge of sexual abuse or sexual abuse prevention concepts; retention of protective behaviours over time; retention of knowledge over time; harm; and disclosures of sexual abuse.

**Main results:** 
This is an update of a Cochrane Review that included 15 trials (up to August 2006). We identified 10 additional trials for the period to September 2014. We excluded one trial from the original review. Therefore, this update includes a total of 24 trials (5802 participants). We conducted several meta-analyses. More than half of the trials in each meta-analysis contained unit of analysis errors.1. Meta-analysis of two trials (n = 102) evaluating protective behaviours favoured intervention (odds ratio (OR) 5.71, 95% confidence interval (CI) 1.98 to 16.51), with borderline low to moderate heterogeneity (Chi&sup2; = 1.37, df = 1, P value = 0.24, I&sup2; = 27%, Tau&sup2; = 0.16). The results did not change when we made adjustments using intraclass correlation coefficients (ICCs) to correct errors made in studies where data were analysed without accounting for the clustering of students in classes or schools.2. Meta-analysis of 18 trials (n = 4657) evaluating questionnaire-based knowledge favoured intervention (standardised mean difference (SMD) 0.61, 95% CI 0.45 to 0.78), but there was substantial heterogeneity (Chi&sup2; = 104.76, df = 17, P value &lt; 0.00001, I&sup2; = 84%, Tau&sup2; = 0.10). The results did not change when adjusted for clustering (ICC: 0.1 SMD 0.66, 95% CI 0.51 to 0.81; ICC: 0.2 SMD 0.63, 95% CI 0.50 to 0.77).3. Meta-analysis of 11 trials (n =1688) evaluating vignette-based knowledge favoured intervention (SMD 0.45, 95% CI 0.24 to 0.65), but there was substantial heterogeneity (Chi&sup2; = 34.25, df = 10, P value &lt; 0.0002, I&sup2; = 71%, Tau&sup2; = 0.08). The results did not change when adjusted for clustering (ICC: 0.1 SMD 0.53, 95% CI 0.32 to 0.74; ICC: 0.2 SMD 0.60, 95% CI 0.31 to 0.89).4. We included four trials in the meta-analysis for retention of knowledge over time. The effect of intervention seemed to persist beyond the immediate assessment (SMD 0.78, 95% CI 0.38 to 1.17; I&sup2; = 84%, Tau&sup2; = 0.13, P value = 0.0003; n = 956) to six months (SMD 0.69, 95% CI 0.51 to 0.87; I&sup2; = 25%; Tau&sup2; = 0.01, P value = 0.26; n = 929). The results did not change when adjustments were made using ICCs.5. We included three studies in the meta-analysis for adverse effects (harm) manifesting as child anxiety or fear. The results showed no increase or decrease in anxiety or fear in intervention participants (SMD -0.08, 95% CI -0.22 to 0.07; n = 795) and there was no heterogeneity (I&sup2; = 0%, P value = 0.79; n=795). The results did not change when adjustments were made using ICCs.6. We inc u ed three studies (n = 1788) in the meta-analysis for disclosure of previous or current sexual abuse. The results favoured intervention (OR 3.56, 95% CI 1.13 to 11.24), with no heterogeneity (I&sup2; = 0%, P value = 0.84). However, adjusting for the effect of clustering had the effect of widening the confidence intervals around the OR (ICC: 0.1 OR 3.04, 95% CI 0.75 to 12.33; ICC: 0.2 OR 2.95, 95% CI 0.69 to 12.61).Insufficient information was provided in the included studies to conduct planned subgroup analyses and there were insufficient studies to conduct meaningful analyses.The quality of evidence for all outcomes included in the meta-analyses was moderate owing to unclear risk of selection bias across most studies, high or unclear risk of detection bias across over half of included studies, and high or unclear risk of attrition bias across most studies. The results should be interpreted cautiously.

**Authors&#039; conclusions:** 
The studies included in this review show evidence of improvements in protective behaviours and knowledge among children exposed to school-based programmes, regardless of the type of programme. The results might have differed had the true ICCs or cluster-adjusted results been available. There is evidence that children&#039;s knowledge does not deteriorate over time, although this requires further research with longer-term follow-up. Programme participation does not generate increased or decreased child anxiety or fear, however there is a need for ongoing monitoring of both positive and negative short- and long-term effects. The results show that programme participation may increase the odds of disclosure, however there is a need for more programme evaluations to routinely collect such data. Further investigation of the moderators of programme effects is required along with longitudinal or data linkage studies that can assess actual prevention of child sexual abuse.
AN  - CD004380
AU  - Walsh,
AU  - K.
AU  - Zwi,
AU  - K.
AU  - Woolfenden,
AU  - S.
AU  - Shlonsky,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004380.pub3
KW  - Schools
KW  - Child Abuse, Sexual [prevention &amp; control]
KW  - Health Knowledge, Attitudes, Practice
KW  - Program Evaluation
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - School-based education programmes for the prevention of child sexual abuse
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004380.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004380.pub3/asset/CD004380.pdf?v=1&amp;t=iw7l2vio&amp;s=d1f2d002c17b310d32efe00c6df50ea8a23d97ee
ER  -
TY  - JOUR
AB  - This meta-analysis concluded that counseling and psychotherapy generally have a small to medium effect in treating anxiety in school-aged youth for termination (waitlist [k = 55; n = 2,959] d = .60[.52-.68]; placebo [k = 14; n = 867] d = .57[.42-.72]; treatment-as-usual [k = 10; n = 371] d = .32[.14-.50]; single group [k = 39; n = 889] d = .42(.37-.48]; and followup (waitlist [k = 22; n = 1,039] d = .51[.39-.63]; placebo [k = 2; n = 134] d = .73[.42-1.03]; treatment-as-usual [k = 9; n = 327] d = .21 [.02-.44]; single group [k = 36; n = 788] d = .58[.51-.65]). 

The findings of 80 clinical trials were synthesized using a random effects model for mean difference and mean gain effect size estimates. No effects of moderating variables were evident. 

Implications for counseling practice and future anxiety outcome research are addressed. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Erford, Bradley T.: berford@loyola.edu Erford, Bradley T.: Loyola University Maryland, Timonium Graduate Center, 2034 Greenspring Drive, Timonium, MD, US, 21093, berford@loyola.edu Erford, Bradley T.: Loyola University Maryland, Timonium, MD, US Kress, Victoria E.: Youngstown State University, Youngstown, OH, US Giguere, Monica: Loyola University Maryland, Timonium, MD, US Cieri, Domenic: Loyola University Maryland, Timonium, MD, US Erford, Breann M.: Ohio State University, OH, US
AN  - 2015-00154-005
AU  - Erford,
AU  - B.
AU  - T.
AU  - Kress,
AU  - V.
AU  - E.
AU  - Giguere,
AU  - M.
AU  - Cieri,
AU  - D.
AU  - Erford,
AU  - B.
AU  - M.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.17744/mehc.37.1.mgj66326868u33g2
DP  - Ovid Technologies
KW  - anxiety disorders, clinical trials, counseling, psychotherapy
KW  - *Anxiety Disorders
KW  - *Counseling
KW  - *Psychotherapy
KW  - *Treatment Outcomes
KW  - Epidemiology
KW  - Neuroses &amp; Anxiety Disorders [3215]
KW  - Psychotherapy &amp; Psychotherapeutic Counseling [3310]
KW  - Human Adulthood (18 yrs &amp; older)
L1  - internal-pdf://3481983474/Erford-2015-Meta-analysis_ Counseling outcomes.pdf
LA  - English
M3  - Meta Analysis
PY  - 2015
SP  - 63-89
T2  - Journal of Mental Health Counseling
TI  - Meta-analysis: Counseling outcomes for youth with anxiety disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-00154-005http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.17744%2Fmehc.37.1.mgj66326868u33g2&amp;issn=1040-2861&amp;isbn=&amp;volume=37&amp;issue=1&amp;spage=63&amp;pages=63-89&amp;date=2015&amp;title=Journal+of+Mental+Health+Counseling&amp;atitle=Meta-analysis%3A+Counseling+outcomes+for+youth+with+anxiety+disorders.&amp;aulast=Erford&amp;pid=%3Cauthor%3EErford%2C+Bradley+T%3C%2Fauthor%3E%3CAN%3E2015-00154-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 37
ER  -
TY  - JOUR
AB  - This study reports findings from a meta-analysis summarizing the effectiveness of brief alcohol interventions for adolescents (age 11-18) and young adults (age 19-30). 

We identified 185 eligible study samples using a comprehensive literature search and synthesized findings using random-effects meta-analyses with robust standard errors. Overall, brief alcohol interventions led to significant reductions in alcohol consumption and alcohol-related problems among adolescents (g = 0.27 and g = 0.19) and young adults (g = 0.17 and g = 0.11). 

These effects persisted for up to 1 year after intervention and did not vary across participant demographics, intervention length, or intervention format. However, certain intervention modalities (e.g., motivational interviewing) and components (e.g., decisional balance, goal-setting exercises) were associated with larger effects. 

We conclude that brief alcohol interventions yield beneficial effects on alcohol-related outcomes for adolescents and young adults that are modest but potentially worthwhile given their brevity and low cost. 

Copyright &copy; 2015 Elsevier Inc. All rights reserved.
AD  - Tanner-Smith, Emily E. Peabody Research Institute, Vanderbilt University, Nashville, TN, USA. Electronic address: e.tanner-smith@vanderbilt.edu. Lipsey, Mark W. Peabody Research Institute, Vanderbilt University, Nashville, TN, USA.
AN  - 25300577
AU  - Tanner-Smith,
AU  - E.
AU  - E.
AU  - Lipsey,
AU  - M.
AU  - W.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jsat.2014.09.001
DP  - Ovid Technologies
J2  - J Subst Abuse Treat
KW  - Adolescent
KW  - Adult
KW  - *Alcohol Drinking/pc [Prevention &amp; Control]
KW  - *Alcohol-Related Disorders/rh [Rehabilitation]
KW  - Child
KW  - Humans
KW  - Motivational Interviewing/mt [Methods]
KW  - *Psychotherapy, Brief/mt [Methods]
KW  - Young Adult
L1  - internal-pdf://3414282891/Tanner-2015-Brief alcohol interventions for ad.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural Review
N1  - Tanner-Smith, Emily E Lipsey, Mark W S0740-5472(14)00192-5
PY  - 2015
SP  - 1-18
T2  - Journal of Substance Abuse Treatment
TI  - Brief alcohol interventions for adolescents and young adults: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25300577http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25300577&amp;id=doi:10.1016%2Fj.jsat.2014.09.001&amp;issn=0740-5472&amp;isbn=&amp;volume=51&amp;issue=&amp;spage=1&amp;pages=1-18&amp;date=2015&amp;title=Journal+of+Substance+Abuse+Treatment&amp;atitle=Brief+alcohol+interventions+for+adolescents+and+young+adults%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Tanner-Smith&amp;pid=%3Cauthor%3ETanner-Smith+EE%3C%2Fauthor%3E%3CAN%3E25300577%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0740547214001925/1-s2.0-S0740547214001925-main.pdf?_tid=be6520c6-04d0-11e7-8802-00000aab0f6b&amp;acdnat=1489068205_e68593000472165fad113159a7e8eef2
VL  - 51
ER  -
TY  - JOUR
AB  - **Background:** 
Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed and treated psychiatric disorders in childhood. Typically, children with ADHD find it difficult to pay attention, they are hyperactive and impulsive.Methylphenidate is the drug most often prescribed to treat children and adolescents with ADHD but, despite its widespread use, this is the first comprehensive systematic review of its benefits and harms.

**Objectives:**
To assess the beneficial and harmful effects of methylphenidate for children and adolescents with ADHD.

**Search methods:** 
In February 2015 we searched six databases (CENTRAL, Ovid MEDLINE, EMBASE, CINAHL, PsycINFO, Conference Proceedings Citations Index), and two trials registers. We checked for additional trials in the reference lists of relevant reviews and included trials. We contacted the pharmaceutical companies that manufacture methylphenidate to request published and unpublished data.

**Selection criteria:**
We included all randomised controlled trials (RCTs) comparing methylphenidate versus placebo or no intervention in children and adolescents aged 18 years and younger with a diagnosis of ADHD. At least 75% of participants needed to have an intellectual quotient of at least 70 (i.e. normal intellectual functioning). Outcomes assessed included ADHD symptoms, serious adverse events, non-serious adverse events, general behaviour and quality of life.

**Data collection and analysis:**
Seventeen review authors participated in data extraction and risk of bias assessment, and two review authors independently performed all tasks. We used standard methodological procedures expected within Cochrane. Data from parallel-group trials and first period data from cross-over trials formed the basis of our primary analyses; separate analyses were undertaken using post-cross-over data from cross-over trials. We used Trial Sequential Analyses to control for type I (5%) and type II (20%) errors, and we assessed and downgraded evidence according to the Grades of Recommendation, Assessment, Development and Evaluation (GRADE) approach for high risk of bias, imprecision, indirectness, heterogeneity and publication bias.

**Main results:** 
The studies.We included 38 parallel-group trials (5111 participants randomised) and 147 cross-over trials (7134 participants randomised). Participants included individuals of both sexes, at a boys-to-girls ratio of 5:1, and participants&#039; ages ranged from 3 to 18 years across most studies (in two studies ages ranged from 3 to 21 years). The average age across all studies was 9.7 years. Most participants were from high-income countries.The duration of methylphenidate treatment ranged from 1 to 425 days, with an average duration of 75 days. Methylphenidate was compared to placebo (175 trials) or no intervention (10 trials). Risk of Bias.All 185 trials were assessed to be at high risk of bias. Primary outcomes. Methylphenidate may improve teacher-rated ADHD symptoms (standardised mean difference (SMD) -0.77, 95% confidence interval (CI) -0.90 to -0.64; 19 trials, 1698 participants; very low-quality evidence). This corresponds to a mean difference (MD) of -9.6 points (95% CI -13.75 to -6.38) on the ADHD Rating Scale (ADHD-RS; range 0 to 72 points; DuPaul 1991a). A change of 6.6 points on the ADHD-RS is considered clinically to represent the minimal relevant difference. There was no evidence that methylphenidate was associated with an increase in serious (e.g. life threatening) adverse events (risk ratio (RR) 0.98, 95% CI 0.44 to 2.22; 9 trials, 1532 participants; very low-quality evidence). The Trial Sequential Analysis-adjusted intervention effect was RR 0.91 (CI 0.02 to 33.2). Secondary outcomes.Among those prescribed methylphenidate, 526 per 1000 (range 448 to 615) experienced non-serious adverse events, compared with 408 per 1000 in the control group. This equates to a 29% increase in the overall risk of any non-serious adverse events (RR 1.29, 95% CI 1.10 to 1.51; 21 trials, 3132 participants; very low-quality evidence). The Trial Sequential Analysis-adjusted int r ention effect was RR 1.29 (CI 1.06 to 1.56). The most common non-serious adverse events were sleep problems and decreased appetite. Children in the methylphenidate group were at 60% greater risk for trouble sleeping/sleep problems (RR 1.60, 95% CI 1.15 to 2.23; 13 trials, 2416 participants), and 266% greater risk for decreased appetite (RR 3.66, 95% CI 2.56 to 5.23; 16 trials, 2962 participants) than children in the control group.Teacher-rated general behaviour seemed to improve with methylphenidate (SMD -0.87, 95% CI -1.04 to -0.71; 5 trials, 668 participants; very low-quality evidence).A change of seven points on the Child Health Questionnaire (CHQ; range 0 to 100 points; Landgraf 1998) has been deemed a minimal clinically relevant difference. The change reported in a meta-analysis of three trials corresponds to a MD of 8.0 points (95% CI 5.49 to 10.46) on the CHQ, which suggests that methylphenidate may improve parent-reported quality of life (SMD 0.61, 95% CI 0.42 to 0.80; 3 trials, 514 participants; very low-quality evidence).

**Authors&#039; conclusions:** 
The results of meta-analyses suggest that methylphenidate may improve teacher-reported ADHD symptoms, teacher-reported general behaviour, and parent-reported quality of life among children and adolescents diagnosed with ADHD. However, the low quality of the underpinning evidence means that we cannot be certain of the magnitude of the effects. Within the short follow-up periods typical of the included trials, there is some evidence that methylphenidate is associated with increased risk of non-serious adverse events, such as sleep problems and decreased appetite, but no evidence that it increases risk of serious adverse events.Better designed trials are needed to assess the benefits of methylphenidate. Given the frequency of non-serious adverse events associated with methylphenidate, the particular difficulties for blinding of participants and outcome assessors point to the advantage of large, &#039;nocebo tablet&#039; controlled trials. These use a placebo-like substance that causes adverse events in the control arm that are comparable to those associated with methylphenidate. However, for ethical reasons, such trials should first be conducted with adults, who can give their informed consent.Future trials should publish depersonalised individual participant data and report all outcomes, including adverse events. This will enable researchers conducting systematic reviews to assess differences between intervention effects according to age, sex, comorbidity, type of ADHD and dose. Finally, the findings highlight the urgent need for large RCTs of non-pharmacological treatments.
AN  - CD009885
AU  - Storebø,
AU  - O.
AU  - J.
AU  - Ramstad,
AU  - E.
AU  - Krogh,
AU  - H.
AU  - B.
AU  - Nilausen,
AU  - T.
AU  - D.
AU  - Skoog,
AU  - M.
AU  - Holmskov,
AU  - M.
AU  - Rosendal,
AU  - S.
AU  - Groth,
AU  - C.
AU  - Magnusson,
AU  - F.
AU  - L.
AU  - Moreira-Maia,
AU  - C.
AU  - R.
AU  - Gillies,
AU  - D.
AU  - Buch
AU  - Rasmussen,
AU  - K.
AU  - Gauci,
AU  - D.
AU  - Zwi,
AU  - M.
AU  - Kirubakaran,
AU  - R.
AU  - Forsbøl,
AU  - B.
AU  - Simonsen,
AU  - E.
AU  - Gluud,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009885.pub2.
KW  - Attention Deficit Disorder with Hyperactivity [drug therapy]
KW  - Central Nervous System Stimulants [adverse effects] [therapeutic use]
KW  - Methylphenidate [adverse effects] [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009885.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009885.pub2/asset/CD009885.pdf?v=1&amp;t=iw7k4v9k&amp;s=6345d5634de5c1c50de94bccf3f74880db0807e4
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Tic disorders (TDs) are common neuropsychiatric disorders in children. Typical antipsychotics, such as haloperidol and pimozide have been prescribed to control tic symptoms as first-line agents. However, adverse effects have led to the use of newer atypical antipsychotics. Aripiprazole is one of alternatives. The aim of this study was to evaluate the efficacy and safety of aripiprazole for children with TDs. 

**METHODS: **
Randomized controlled trials (RCTs), quasi-RCTs and control studies evaluating aripiprazole for children with tic disorders were identified from PubMed, Embase, Cochrane library, Cochrane Central, four Chinese database and relevant reference lists. Quality assessment referred to the Cochrane Handbook for Systematic Reviews of Interventions. 

**RESULTS: **
Twelve studies involving 935 participants were included. The general quality of included studies was poor. Only one study used placebo as a control and others used positive drug controls. Participants were aged between 4 and 18 years. The period of treatment ranged from 8 to 12 weeks. Seven studies (N = 600 patients) used the YGTSS scale as the outcome measurement, and there was no significant difference in reduction of the total YGTSS score between the aripiprazole and positive control groups (MD =-0.48, 95 % CI [-6.22, 5.26], P = 0.87, I(2)= 87 %). Meta-analysis of four of the studies (N = 285 patients) that compared aripiprazole with haloperidol showed that there was no significant difference in reduction of the total YGTSS score (MD = 2.50, 95 % CI [-6.93, 11.92], P = 0.60, I(2)= 88 %). Meta-analysis of two studies (N = 255 patients) that compared aripiprazole with tiapride showed that there was no significant difference in reduction of the total YGTSS score (MD =-3.15, 95 % CI [-11.38, 5.09], P = 0.45, I(2)= 86 %). Adverse events (AEs) were reported in 11 studies. Drowsiness (5.1 %-58.1 %), increased appetite (3.2 %-25.8 %), nausea (2 %-18.8 %) and headache (2 %-16.1 %) were common AEs. 

**CONCLUSION: **
In conclusion, aripiprazole appears to be a promising therapy for children with TDs. Further well-conducted RCTs are required to confirm this issue.
AD  - Yang, Chun-Song. Department of Pharmacy, Evidence-based Pharmacy Center, West China second hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. yangchunsong_123@126.com. Yang, Chun-Song. West China School of Public Health, Sichuan University, Chengdu, China. yangchunsong_123@126.com. Huang, Hong. Department of Pharmacy, Evidence-based Pharmacy Center, West China second hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. hh_ok7303@163.com. Zhang, Ling-Li. Department of Pharmacy, Evidence-based Pharmacy Center, West China second hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. zhlingli@sina.com. Zhang, Ling-Li. West China Second University Hospital, Sichuan University, No.20,Third Section, Renmin NanLu, Chengdu, Sichuan, 610041, People&#039;s Republic of China. zhlingli@sina.com. Zhu, Cai-Rong. West China School of Public Health, Sichuan University, Chengdu, China. cairong.zhu@hotmail.com. Guo, Qin. Department of Pediatrics, West China second hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, China. joy1122@163.com.
AN  - 26220447
AU  - Yang,
AU  - C.
AU  - S.
AU  - Huang,
AU  - H.
AU  - Zhang,
AU  - L.
AU  - L.
AU  - Zhu,
AU  - C.
AU  - R.
AU  - Guo,
AU  - Q.
DA  - Jul 29
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/s12888-015-0504-z
DP  - Ovid Technologies
J2  - BMC Psychiatry
KW  - Adolescent
KW  - *Antipsychotic Agents/tu [Therapeutic Use]
KW  - *Aripiprazole/tu [Therapeutic Use]
KW  - Child
KW  - Child, Preschool
KW  - Haloperidol/tu [Therapeutic Use]
KW  - Humans
KW  - Randomized Controlled Trials as Topic/mt [Methods]
KW  - *Tic Disorders/di [Diagnosis]
KW  - *Tic Disorders/dt [Drug Therapy]
KW  - Tic Disorders/px [Psychology]
KW  - Treatment Outcome
KW  - 0 (Antipsychotic Agents)
KW  - 82VFR53I78 (Aripiprazole)
KW  - J6292F8L3D (Haloperidol)
L1  - internal-pdf://2590242274/Yang-2015-Aripiprazole for the treatment of ti.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Yang, Chun-Song Huang, Hong Zhang, Ling-Li Zhu, Cai-Rong Guo, Qin 10.1186/s12888-015-0504-z
PY  - 2015
SP  - 179
T2  - BMC Psychiatry
TI  - Aripiprazole for the treatment of tic disorders in children: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26220447http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26220447&amp;id=doi:10.1186%2Fs12888-015-0504-z&amp;issn=1471-244X&amp;isbn=&amp;volume=15&amp;issue=1&amp;spage=179&amp;pages=179&amp;date=2015&amp;title=BMC+Psychiatry&amp;atitle=Aripiprazole+for+the+treatment+of+tic+disorders+in+children%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Yang&amp;pid=%3Cauthor%3EYang+CS%3C%2Fauthor%3E%3CAN%3E26220447%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518630/pdf/12888_2015_Article_504.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - **Background:** 
It has been suggested that the severity of autism spectrum disorder (ASD) symptoms is positively correlated with the level of circulating or stored toxic metals, and that excretion of these heavy metals, brought about by the use of pharmaceutical chelating agents, results in improved symptoms.

**Objectives:** 
To assess the potential benefits and adverse effects of pharmaceutical chelating agents (referred to as chelation therapy throughout this review) for autism spectrum disorder (ASD) symptoms.Search methods: We searched the following databases on 6 November 2014: CENTRAL, Ovid MEDLINE, Ovid MEDLINE In-Process, Embase, PsycINFO, Cumulative Index to Nursing and Allied Health Literature (CINAHL) and 15 other databases, including three trials registers. In addition we checked references lists and contacted experts.

**Selection criteria:** 
All randomised controlled trials of pharmaceutical chelating agents compared with placebo in individuals with ASD.

**Data collection and analysis:** 
Two review authors independently selected studies, assessed them for risk of bias and extracted relevant data. We did not conduct a meta-analysis, as only one study was included.

**Main results:** We excluded nine studies because they were non-randomised trials or were withdrawn before enrolment. We included one study, which was conducted in two phases. During the first phase of the study, 77 children with ASD were randomly assigned to receive seven days of glutathione lotion or placebo lotion, followed by three days of oral dimercaptosuccinic acid (DMSA). Forty-nine children who were found to be high excreters of heavy metals during phase one continued on to phase two to receive three days of oral DMSA or placebo followed by 11 days off, with the cycle repeated up to six times. The second phase thus assessed the effectiveness of multiple doses of oral DMSA compared with placebo in children who were high excreters of heavy metals and who received a three-day course of oral DMSA. Overall, no evidence suggests that multiple rounds of oral DMSA had an effect on ASD symptoms.

**Authors&#039; conclusions:** 
This review included data from only one study, which had methodological limitations. As such, no clinical trial evidence was found to suggest that pharmaceutical chelation is an effective intervention for ASD. Given prior reports of serious adverse events, such as hypocalcaemia, renal impairment and reported death, the risks of using chelation for ASD currently outweigh proven benefits. Before further trials are conducted, evidence that supports a causal link between heavy metals and autism and methods that ensure the safety of participants are needed.
AN  - CD010766
AU  - James,
AU  - S.
AU  - Stevenson,
AU  - S.
AU  - W.
AU  - Silove,
AU  - N.
AU  - Williams,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd010766.pub2
KW  - Chelation Therapy [adverse effects]
KW  - Administration, Oral
KW  - Chelating Agents [administration &amp; dosage] [adverse effects]
KW  - Child Development Disorders, Pervasive [blood] [therapy]
KW  - Glutathione [administration &amp; dosage]
KW  - Metals, Heavy [blood]
KW  - Randomized Controlled Trials as Topic
KW  - Skin Cream [administration &amp; dosage]
KW  - Succimer [administration &amp; dosage] [adverse effects]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Behav
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Chelation for autism spectrum disorder (ASD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD010766.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD010766.pub2/asset/CD010766.pdf?v=1&amp;t=iw7j0puq&amp;s=7843e6d1272b7911e5ab14168f1d6a6aa9a4b719
ER  -
TY  - JOUR
AB  - Although cognitive&ndash;behavioural (CB) treatments are recognised as evidence-based interventions for depression and other disorders in adolescents, their efficacy in reducing suicidal and self-harm behaviours in this group remains equivocal. 

First, a systematic review of the literature was carried out (N = 25 studies) on CB treatments for adolescents who presented suicidal ideation, had made suicide attempts, or engaged in self-harm. Results suggest that the scientific quality of past studies is suboptimal. 

Second, a meta-analysis of the pooled data of 14 CB treatment studies was conducted using a pre&ndash;post control group design. Results indicate a significant treatment effect in reducing suicidal ideation (n = 13/14 studies; g = &minus;.40, 95% CI [&minus;.30, .49], z = 7.95, p = .001). 

A significant effect was observed also with respect to self-harm (n = 8/14 studies; g = &minus;.27, 95% CI [&minus;.17, .38], z = 4.96, p = .001). However, no significant effect was found for suicide attempts (n = 6/14 studies; g = &minus;.01, 95% CI [&minus;.13, .14], z = .07, p = .94). 

The poor effect observed in this case could be due to low baseline prevalence of suicide attempts in most studies owing to active exclusion of adolescents at high risk for suicide.
AD  - Labelle, Real: labelle.real@uqam.ca Labelle, Real: Departement de psychologie et Centre de recherche et d&#039;intervention sur le suicide et l&#039;euthanasie, Universite du Quebec a Montreal, Case postale 8888, succursale Centre-Ville, Montreal, PQ, Canada, H3C 3P8, labelle.real@uqam.ca Labelle, Real: Departement de psychologie et Centre de recherche et d&#039;intervention sur le suicide et l&#039;euthanasie, Universite du Quebec a Montreal, Montreal, PQ, Canada Pouliot, Louise: Departement de psychologie et Centre de recherche et d&#039;intervention sur le suicide et l&#039;euthanasie, Universite du Quebec a Montreal, Montreal, PQ, Canada Janelle, Alain: Departement de psychologie et Centre de recherche et d&#039;intervention sur le suicide et l&#039;euthanasie, Universite du Quebec a Montreal, Montreal, PQ, Canada
AN  - 2015-23497-001
AU  - Labelle,
AU  - R.
AU  - Pouliot,
AU  - L.
AU  - Janelle,
AU  - A.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/a0039159
DP  - Ovid Technologies
KW  - cognitive-behavioural, treatment, self-harm, adolescent, suicidal behaviors, suicidal ideation, suicide attempts, self-harm
KW  - *Adolescent Psychopathology
KW  - *Attempted Suicide
KW  - *Cognitive Behavior Therapy
KW  - *Self-Injurious Behavior
KW  - *Suicidal Ideation
KW  - At Risk Populations
KW  - Suicide
KW  - Behavior Disorders &amp; Antisocial Behavior [3230]
KW  - Cognitive Therapy [3311]
KW  - Human Male Female Inpatient Outpatient Childhood (birth-12 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older) Young Adulthood (18-29 yrs)
KW  - United Kingdom, US
L1  - internal-pdf://2852336055/368.pdf
LA  - English
M3  - Empirical Study; Literature Review; Systematic Review; Meta Analysis; Qualitative Study
PY  - 2015
SP  - 368-378
T2  - Canadian Psychology/Psychologie canadienne
TI  - A systematic review and meta-analysis of cognitive behavioural treatments for suicidal and self-harm behaviours in adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-23497-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2Fa0039159&amp;issn=0708-5591&amp;isbn=&amp;volume=56&amp;issue=4&amp;spage=368&amp;pages=368-378&amp;date=2015&amp;title=Canadian+Psychology%2FPsychologie+canadienne&amp;atitle=A+systematic+review+and+meta-analysis+of+cognitive+behavioural+treatments+for+suicidal+and+self-harm+behaviours+in+adolescents.&amp;aulast=Labelle&amp;pid=%3Cauthor%3ELabelle%2C+Real%3C%2Fauthor%3E%3CAN%3E2015-23497-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 56
ER  -
TY  - JOUR
AB  - **Background:** 
Long chain polyunsaturated fatty acids (LCPUFA), especially docosahexaenoic acid (DHA), are the most abundant fatty acids in the brain and are necessary for growth and maturation of an infant&#039;s brain and retina. LCPUFAs are named ?essential? because they cannot be synthesised efficiently by the human body and come from maternal diet. It remains controversial whether LCPUFA supplementation to breastfeeding mothers is beneficial for the development of their infants.

**Objectives:** 
To assess the effectiveness and safety of supplementation with LCPUFA in breastfeeding mothers in the cognitive and physical development of their infants as well as safety for the mother and infant.

**Search methods:** 
We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (6 August 2014), CENTRAL (Cochrane Library 2014, Issue 8), PubMed (1966 to August 2014), EMBASE (1974 to August 2014), LILACS (1982 to August 2014), Google Scholar (August 2014) and reference lists of published narrative and systematic reviews.

**Selection criteria:** 
Randomised controlled trials or cluster-randomised controlled trials evaluating the effects of LCPUFA supplementation on breastfeeding mothers (including the pregnancy period) and their infants.

**Data collection and analysis:** 
Two review authors independently assessed eligibility and trial quality, performed data extraction and evaluated data accuracy.

**Main results:** 
We included eight randomised controlled trials involving 1567 women. All the studies were performed in high-income countries. The longest follow-up was seven years.We report the results from the longest follow-up time point from included studies. Overall, there was moderate quality evidence as assessed using the GRADE approach from these studies for the following outcomes measured beyond 24 months age of children: language development and child weight. There was low-quality evidence for the outcomes: Intelligence or solving problems ability, psychomotor development, child attention, and child visual acuity.We found no significant difference in children&#039;s neurodevelopment at long-term follow-up beyond 24 months: language development (standardised mean difference (SMD) -0.27, 95% confidence interval (CI) -0.56 to 0.02; two trials, 187 participants); intelligence or problem-solving ability (three trials, 238 participants; SMD 0.00, 95% CI -0.36 to 0.36); psychomotor development (SMD -0.11, 95% CI -0.48 to 0.26; one trial, 113 participants); motor development (SMD -0.23, 95% CI -0.60 to 0.14; one trial, 115 participants), or in general movements (risk ratio, RR, 1.12, 95% CI 0.58 to 2.14; one trial, 77 participants; at 12 weeks of life). However, child attention scores were better at five years of age in the group of children whose mothers had received supplementation with fatty acids (mean difference (MD) 4.70, 95% CI 1.30 to 8.10; one study, 110 participants)). In working memory and inhibitory control, we found no significant difference (MD -0.02 95% CI -0.07 to 0.03 one trial, 63 participants); the neurological optimality score did not present any difference (P value: 0.55).For child visual acuity, there was no significant difference (SMD 0.33, 95% CI -0.04 to 0.71; one trial, 111 participants).For growth, there were no significant differences in length (MD -0.39 cm, 95% CI -1.37 to 0.60; four trials, 441 participants), weight (MD 0.13 kg, 95% CI -0.49 to 0.74; four trials, 441 participants), and head circumference (MD 0.15 cm, 95% CI -0.27 to 0.58; three trials, 298 participants). Child fat mass and fat mass distribution did not differ between the intervention and control group (MD 2.10, 95% CI -0.48 to 4.68; one trial, 115 participants, MD -0.50, 95% CI -1.69 to 0.69; one trial, 165 participants, respectively).One study (117 infants) reported a significant difference in infant allergy at short-term follow-up (risk ratio (RR) 0.13, 95% CI 0.02 to 0.95), but not at medium-term follow-up (RR 0.52, 95% CI 0.17 to 1.59).We found no significant difference in two trials evaluating postpartum depression. Data were not possible to be pooled u to differences in the describing of the outcome. One study (89 women) did not find any significant difference between the LCPUFA supplementation and the control group at four weeks postpartum (MD 1.00, 95%CI -1.72 to 3.72).No adverse effects were reported.

**Authors&#039; conclusions:** 
Based on the available evidence, LCPUFA supplementation did not appear to improve children&#039;s neurodevelopment, visual acuity or growth. In child attention at five years of age, weak evidence was found (one study) favouring the supplementation. Currently, there is inconclusive evidence to support or refute the practice of giving LCPUFA supplementation to breastfeeding mothers in order to improve neurodevelopment or visual acuity.
AN  - CD007901
AU  - Delgado,
AU  - Noguera,
AU  - M.
AU  - N.
AU  - Calvache,
AU  - J.
AU  - A.
AU  - Cosp,
AU  - X.
AU  - B.
AU  - Kotanidou,
AU  - E.
AU  - P.
AU  - Galli-Tsinopoulou,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007901.pub3
KW  - Breast Feeding
KW  - Child Development
KW  - Growth
KW  - Attention
KW  - Fatty Acids, Unsaturated [administration &amp; dosage]
KW  - Intelligence
KW  - Language Development
KW  - Problem Solving
KW  - Psychomotor Performance
KW  - Randomized Controlled Trials as Topic
KW  - Visual Acuity
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Infant[checkword]
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Supplementation with long chain polyunsaturated fatty acids (LCPUFA) to breastfeeding mothers for improving child growth and development
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007901.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007901.pub3/asset/CD007901.pdf?v=1&amp;t=iw7l8fie&amp;s=64647b062a3ec325b7cf8c3e5cfe39842028181e
ER  -
TY  - JOUR
AB  - This meta-analysis examined the effect experimental sleep restriction has on youth&#039;s attention and hyperactivity outcomes. 

Thirteen published studies containing 17 independent samples were included (N = 496). 

Random- and fixed-effects models were used to estimate pooled effect sizes and moderator effects, respectively. 

Results indicate that sleep-restricted youth had significantly worse attention outcomes than youth with extended sleep, but no differences were evident regarding hyperactivity. Significant moderators of this effect included age and sex. 

These results have important implications for both the prevention and treatment of attention problems, highlighting the need for health professionals to screen for and treat underlying sleep issues.
AN  - 26151610
AU  - Lundahl,
AU  - A.
AU  - Kidwell,
AU  - K.
AU  - M.
AU  - Van
AU  - Dyk,
AU  - T.
AU  - R.
AU  - Nelson,
AU  - T.
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/87565641.2014.939183
L1  - internal-pdf://3304260533/Lundahl-2015-A Meta-Analysis of the Effect of.pdf
PY  - 2015
SP  - 104-21
T2  - Developmental Neuropsychology
TI  - A Meta-Analysis of the Effect of Experimental Sleep Restriction on Youth&#039;s Attention and Hyperactivity
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=26151610
UR  - https://www.tandfonline.com/doi/pdf/10.1080/87565641.2014.939183?needAccess=true
VL  - 40
ER  -
TY  - JOUR
AB  - **PURPOSE: **
To review the characteristics and effects Internet-based youth smoking prevention and cessation programs. 

**DESIGN: **
Systematic review of published articles in peer-reviewed journals in the past 10 years, focused on Internet-based youth smoking prevention and cessation programs. 

**METHODS: **
Twelve articles were selected based on the following criteria: studies reporting the outcomes of Internet-based smoking cessation or prevention intervention programs for adolescents who are younger than 24 years. 

**FINDINGS: **
The components of youth Internet-based smoking intervention programs are analyzed based on study features (i.e., sample, design, theoretical basis, analysis, outcome measures) and program characteristics (i.e., focus, setting, frequency, duration, intensity, and different components) that make the programs effective. The most common components of effective Internet-based programs are identified as the following: the use of multimedia, tailored approaches, personalized feedback, and interactive features. 

**CONCLUSIONS: **
The characteristics and effects of the programs vary, but most programs show positive results in youth smoking prevention and cessation in spite of the studies&#039; limitations. 

**CLINICAL RELEVANCE:**
The evidence from this review provides useful information of recent efforts related to Internet-based youth smoking prevention and cessation programs, which can have significant clinical implications in developing future innovative youth smoking prevention and intervention programs.

Copyright &copy; 2014 Sigma Theta Tau International.
AD  - Park,Eunhee. Beta Kappa, Doctoral Student, University of Virginia, Charlottesville, VA, USA.
AN  - 25130325
AU  - Park,
AU  - E.
AU  - Drake,
AU  - E.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jnu.12104
DP  - Ovid Technologies
J2  - J Nurs Scholarsh
KW  - Adolescent Humans *Internet Program Evaluation *Smoking/pc [Prevention &amp; Control] *Smoking Cessation/mt [Methods] Young Adult
LA  - English
M3  - Review
N1  - Park, Eunhee Drake, Emily
PY  - 2015
SP  - 43-50
T2  - Journal of Nursing Scholarship
TI  - Systematic review: internet-based program for youth smoking prevention and cessation
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25130325
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25130325&amp;id=doi:10.1111%2Fjnu.12104&amp;issn=1527-6546&amp;isbn=&amp;volume=47&amp;issue=1&amp;spage=43&amp;pages=43-50&amp;date=2015&amp;title=Journal+of+Nursing+Scholarship&amp;atitle=Systematic+review%3A+internet-based+program+for+youth+smoking+prevention+and+cessation.&amp;aulast=Park&amp;pid=%3Cauthor%3EPark+E%3C%2Fauthor%3E%3CAN%3E25130325%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/jnu.12104/asset/jnu12104.pdf?v=1&amp;t=ib3if8f0&amp;s=e533906e118dfed134db64c42ddeddf3a82a2dbf
VL  - 47
ER  -
TY  - JOUR
AB  - **Aims: **
We investigate the effect of motivational interviewing (MI), delivered in a brief intervention during an emergency care contact, on the alcohol consumption of young people who screen positively for present or previous risky alcohol consumption. 

**Methods:** 
MEDLINE, CINAHL, EMBASE, PsycARTICLES, PsycINFO, PSYNDEX and Scopus were searched for randomized controlled trials with adolescents or young adults that compared MI in an emergency care setting to control conditions and measured drinking outcomes. 

**Results: **
Six trials with 1433 participants, aged 13-25 years, were included in the systematic review and meta-analysis. MI was never less efficacious than a control intervention. Two trials found significantly more reduction in one or more measures of alcohol consumption in the MI intervention group. One trial indicated that MI may be used most effectively in young people with high-volume alcohol consumption. Separate random effects meta-analyses were performed based on the highest impact that MI added on reducing the drinking frequency and the drinking quantity at any point in time during the different study periods. Their results were expressed as standardized mean differences (SMDs). The frequency of drinking alcohol decreased significantly more after MI than after control interventions (SMD &lt; -0.17, P &lt; 0.03). In addition, MI reduced the drinking quantity further than control interventions in a meta-analysis of the subset of trials that were implemented in the USA (SMD = -0.12, P = 0.04). Meta-analyses of the smallest mean differences between MI and control groups detected no differences in alcohol use (SMD &lt; 0.02, P &gt; 0.38). 

**Conclusion: **
MI appears at least as effective and may possibly be more effective than other brief interventions in emergency care to reduce alcohol consumption in young people. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Kohler, Stefan: stefan.kohler@charite.de Kohler, Stefan, stefan.kohler@charite.de Kohler, Stefan: Institute for Social Medicine, Epidemiology and Health Economics, Charite-Universitatsmedizin Berlin, Berlin, Germany Hofmann, Anjuna: IB-GIS mbh Medizinische Akademie, Berlin, Germany
AN  - 2015-07142-001
AU  - Kohler,
AU  - S.
AU  - Hofmann,
AU  - A.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1093/alcalc/agu098
DP  - Ovid Technologies
KW  - motivational interviewing, emergency care, alcohol consumption, intervention group, drinking outcomes
KW  - *Alcohols
KW  - *Intervention
KW  - *Motivational Interviewing
KW  - Interviewing
KW  - Motivation
KW  - Psychotherapy &amp; Psychotherapeutic Counseling [3310]
KW  - Adolescent
KW  - Adult
KW  - Alcohol Drinking
KW  - Binge Drinking
KW  - Emergency Service, Hospital
KW  - Humans
KW  - Motivational Interviewing
KW  - Young Adult
KW  - Human
L1  - internal-pdf://3889113669/agu098.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2015
SP  - 107-117
T2  - Alcohol and Alcoholism
TI  - Can motivational interviewing in emergency care reduce alcohol consumption in young people? A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-07142-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1093%2Falcalc%2Fagu098&amp;issn=0735-0414&amp;isbn=&amp;volume=50&amp;issue=2&amp;spage=107&amp;pages=107-117&amp;date=2015&amp;title=Alcohol+and+Alcoholism&amp;atitle=Can+motivational+interviewing+in+emergency+care+reduce+alcohol+consumption+in+young+people%3F+A+systematic+review+and+meta-analysis.&amp;aulast=Kohler&amp;pid=%3Cauthor%3EKohler%2C+Stefan%3C%2Fauthor%3E%3CAN%3E2015-07142-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 50
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
ASC (autism spectrum conditions) may result from a failure of striatal beta endorphins to diminish with maturation. Many symptoms of ASC resemble behaviours induced in animals or humans by opiate administration, including decreased socialisation, diminished crying, repetitive stereotypies, insensitivity to pain and motor hyperactivity. Naltrexone, an opioid antagonist, has been used in the management of children with ASC and can produce a clinically significant reduction in the serious and life-threatening behaviour of self-injury for individuals who have not been responsive to any other type of treatment and is important for this reason. It was therefore appropriate to reconsider the available evidence and a systematic review was undertaken. 

**METHODS:** 
Four electronic databases were searched for relevant journal articles. In addition, cross-referencing of pertinent reviews and a hand search for articles in major international intellectual disability (ID) journals between the years 2010 and 2012 was carried out to ensure that all relevant articles were identified. We also searched databases for unpublished clinical trials to overcome publication bias. Each database was searched up to present (February 2013) with no restrictions on the date of publication. The search terms consisted of broad expressions used to describe ID and autistic spectrum disorder as well as terms relating to opioid antagonists and specific drugs. All studies identified by the electronic database search and hand search were examined on the basis of title alone for relevance and duplication. The abstracts of the remaining papers were then scrutinised against the inclusion criteria. Where abstracts failed to provide adequate information, the full texts for these papers were obtained. All the full texts were then evaluated against the inclusion proforma. Two reviewers carried out all the stages of the process independently. The reviewers met to discuss their selections and where disagreements arose, these were settled by discussion with a member of the study group. Data from each study meeting the inclusion criteria were extracted on a pre-piloted data extraction form. The quality of each study was further assessed using the Jadad scale, a tool developed to assess the quality of randomised controlled trials. 

**RESULTS: **
155 children participated in 10 studies; 27 received placebo. Of the 128 that received naltrexone 98 (77%) showed statistically significant improvement in symptoms of irritability and hyperactivity. Side effects were mild and the drug was generally well tolerated. 

**CONCLUSIONS:**
Naltrexone may improve hyperactivity and restlessness in children with autism but there was not sufficient evidence that it had an impact on core features of autism in majority of the participants. It is likely that a subgroup of children with autism and abnormal endorphin levels may respond to naltrexone and identifying the characteristics of these children must become a priority.

Copyright &copy; 2014 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley &amp; Sons Ltd.
AD  - Roy,A. Manchester Medical School, Manchester, UK.
AN  - 24589346
AU  - Roy,
AU  - A.
AU  - Roy,
AU  - M.
AU  - Deb,
AU  - S.
AU  - Unwin,
AU  - G.
AU  - Roy,
AU  - A.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/jir.12122
DP  - Ovid Technologies
J2  - J Intellect Disabil Res
LA  - English
N1  - Roy, A Roy, M Deb, S Unwin, G
PY  - 2015
SP  - 293-306
T2  - Journal of Intellectual Disability Research
TI  - Are opioid antagonists effective in attenuating the core symptoms of autism spectrum conditions in children: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24589346
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24589346&amp;id=doi:10.1111%2Fjir.12122&amp;issn=0964-2633&amp;isbn=&amp;volume=59&amp;issue=4&amp;spage=293&amp;pages=293-306&amp;date=2015&amp;title=Journal+of+Intellectual+Disability+Research&amp;atitle=Are+opioid+antagonists+effective+in+attenuating+the+core+symptoms+of+autism+spectrum+conditions+in+children%3A+a+systematic+review.&amp;aulast=Roy&amp;pid=%3Cauthor%3ERoy+A%3C%2Fauthor%3E%3CAN%3E24589346%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/jir.12122/asset/jir12122.pdf?v=1&amp;t=ib3ib7lf&amp;s=45004568b4c9186e6e22cc978475e15c1e634bd0
VL  - 59
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
This systematic review evaluated the effectiveness of exposure-based psychological and physical interventions for the management of high levels of needle fear and/or phobia and fainting in children and adults. 

**DESIGN/METHODS: **
A systematic review identified relevant randomized and quasi-randomized controlled trials of children, adults, or both with high levels of needle fear, including phobia (if not available, then populations with other specific phobias were included). Critically important outcomes were self-reported fear specific to the feared situation and stimulus (psychological interventions) or fainting (applied muscle tension). Data were pooled using standardized mean difference (SMD) or relative risk with 95% confidence intervals. 

**RESULTS: **
The systematic review included 11 trials. In vivo exposure-based therapy for children 7 years and above showed benefit on specific fear (n=234; SMD: -1.71 [95% CI: -2.72, -0.7]). In vivo exposure-based therapy with adults reduced fear of needles posttreatment (n=20; SMD: -1.09 [-2.04, -0.14]) but not at 1-year follow-up (n=20; SMD: -0.28 [-1.16, 0.6]). Compared with single session, a benefit was observed for multiple sessions of exposure-based therapy posttreatment (n=93; SMD: -0.66 [-1.08, -0.24]) but not after 1 year (n=83; SMD: -0.37 [-0.87, 0.13]). Non in vivo e.g., imaginal exposure-based therapy in children reduced specific fear posttreatment (n=41; SMD: -0.88 [-1.7, -0.05]) and at 3 months (n=24; SMD: -0.89 [-1.73, -0.04]). Non in vivo exposure-based therapy for adults showed benefit on specific fear (n=68; SMD: -0.62 [-1.11, -0.14]) but not procedural fear (n=17; SMD: 0.18 [-0.87, 1.23]). Applied tension showed benefit on fainting posttreatment (n=20; SMD: -1.16 [-2.12, -0.19]) and after 1 year (n=20; SMD: -0.97 [-1.91, -0.03]) compared with exposure alone. 

**CONCLUSIONS: **
Exposure-based psychological interventions and applied muscle tension show evidence of benefit in the reduction of fear in pediatric and adult populations.
AD  - McMurtry, C Meghan. *Department of Psychology, University of Guelph, Guelph +Children&#039;s Health Research Institute ++Department of Paediatrics, Western University, London Leslie Dan Faculty of Pharmacy ++++Department of Psychiatry ##Health Policy Management and Evaluation, Faculty of Medicine, University of Toronto PThe Hospital for Sick Children #Department of Psychology, Ryerson University ++Department of Psychology, York University PPMount Sinai Hospital, Toronto, ON **Department of Psychology, University of Regina, Regina, SK Departments of Pediatrics, Psychology &amp; Neuroscience, Dalhousie University Centre for Pediatric Pain Research, IWK Health Centre, Halifax, NS, Canada Department of Psychology, University of Calgary, AB, Canada.
AN  - 26352916
AU  - McMurtry,
AU  - A.
AU  - M.
AU  - Noel,
AU  - M.
AU  - Taddio,
AU  - A.
AU  - Antony,
AU  - M.
AU  - M.
AU  - Asmundson,
AU  - G.
AU  - J.
AU  - Riddell,
AU  - R.
AU  - P.
AU  - Chambers,
AU  - C.
AU  - T.
AU  - Shah,
AU  - V.
AU  - HelpinKids
AU  - AdultsTeam
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/AJP.0000000000000273
DP  - Ovid Technologies
J2  - Clin J Pain
KW  - Adolescent
KW  - Adult
KW  - Databases, Bibliographic/sn [Statistics &amp; Numerical Data]
KW  - *Fear/px [Psychology]
KW  - Humans
KW  - *Needles/ae [Adverse Effects]
KW  - *Phobic Disorders/et [Etiology]
KW  - Phobic Disorders/px [Psychology]
KW  - *Psychotherapy/mt [Methods]
KW  - *Randomized Controlled Trials as Topic
L1  - internal-pdf://1315010411/McMurtry-2015-Interventions for Individuals Wi.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - McMurtry, C Meghan Noel, Melanie Taddio, Anna Antony, Martin M Asmundson, Gordon J G Riddell, Rebecca Pillai Chambers, Christine T Shah, Vibhuti HELPinKids&amp;Adults Team MacDonald NE Rogers J Bucci L Mousmanis P Lang E Halperin SA Bowles S Halpert C Ipp M Rieder M Robson K Uleryk E Dubey V Hanrahan A Lockett D Scott J Votta Bleeker E 00002508-201510001-00011
PY  - 2015
SP  - S109-23
T2  - Clinical Journal of Pain
TI  - Interventions for Individuals With High Levels of Needle Fear: Systematic Review of Randomized Controlled Trials and Quasi-Randomized Controlled Trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=26352916http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:26352916&amp;id=doi:10.1097%2FAJP.0000000000000273&amp;issn=0749-8047&amp;isbn=&amp;volume=31&amp;issue=10&amp;spage=S109&amp;pages=S109-23&amp;date=2015&amp;title=Clinical+Journal+of+Pain&amp;atitle=Interventions+for+Individuals+With+High+Levels+of+Needle+Fear%3A+Systematic+Review+of+Randomized+Controlled+Trials+and+Quasi-Randomized+Controlled+Trials.&amp;aulast=McMurtry&amp;pid=%3Cauthor%3EMcMurtry+CM%3C%2Fauthor%3E%3CAN%3E26352916%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900415/pdf/ajp-31-s109.pdf
VL  - 31
ER  -
TY  - JOUR
AB  - Bakgrunn
Denne artikkelen er en kunnskapsoppsummering for effektene av tiltaket TIBIR &ndash; Rådgiverintervensjonen i Norge. Artikkelen er en revisjon av en tidligere beskrivelse av det samme tiltaket i Ungsinn (Mørch, 2012), men videreutviklet i henhold til Ungsinn sine nye prosedyrer og kriterier. Rådgiverintervensjonen er en korttids foreldreveiledningsintervensjon på 3-5 sesjoner. Målgruppen er familier med barn mellom 3-12 år som viser tegn på begynnende eller er i risiko for å utvikle atferdsproblemer. Intervensjonen er et av totalt seks tiltak i programpakken Tidlig intervensjon for barn i risiko (TIBIR). Atferdssenteret har utviklet og er tiltakseier for tiltaket.

Metode
Embase, Medline og Psykinfo, NORART Cochrane, Cristin, NORA, SCOPUS og SweMed. To artikler ble inkludert.

Resultateter
Resultatene omfatter en oppsummering av tiltakets beskrivelse, foreliggende effektstudier, forskningsmetodisk kvalitet og implementeringskvalitet. Rådgiverintervensjonen er svært godt beskrevet i flere dokumenter blant annet gjennom en detaljert manual. Det foreligger &eacute;n nordisk RCT effektivitetsstudie med målinger pre-post og 6 mnd etter avsluttet intervensjon. Studien er gjennomført med god kvalitet, og det er funnet signifikante effekter på relevante utfallsmål og effektene funnet vurderes til å være av praktisk betydning. Tiltaket har gode systemer for å sikre god implementeringskvalitet, noe som gjør det sannsynlig at de positive resultatene fra studien også vil finne sted når tiltaket brukes i vanlig praksis.

Konklusjon
Selv om tiltaket tilfredsstiller kravene for høyeste evidensnivå på nesten alle områder, vurderes behovet for flere uavhengige studier som nødvendig for å kunne konkludere med at et tiltak har sterk dokumentasjon på effekt. TIBIR-rådegiverintervensjonen klassifiseres på evidensnivå 4 &ndash; Tiltak med tilfredsstillende dokumentasjon på effekt.
AU  - Eng,
AU  - H.,
AU  - Patras,
AU  - J.,
AU  - Handegård,
AU  - B.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - URL
PY  - 2015
T2  - Ungsinn: Tidsskrift for virksomme tiltak for barn og unge
TI  - Kunnskapsoppsummering og klassifisering av tiltaket: TIBIR &ndash; Rådgiverintervensjonen (2.utg.)
UR  - https://ungsinn.no/post_tiltak_arkiv/tibir-radgiverintervensjonen/
VL  - 2
ER  -
TY  - JOUR
AB  - The popularity, demand, and increased federal and private funding for after-school programs have resulted in a marked increase in after-school programs over the past two decades. 

After-school programs are used to prevent adverse outcomes, decrease risks, or improve functioning with at-risk youth in several areas, including academic achievement, crime and behavioral problems, socio-emotional functioning, and school engagement and attendance; however, the evidence of effects of after-school programs remains equivocal. 

This systematic review and meta-analysis, following Campbell Collaboration guidelines, examined the effects of after-school programs on externalizing behaviors and school attendance with at-risk students. A systematic search for published and unpublished literature resulted in the inclusion of 24 studies. 

A total of 64 effect sizes (16 for attendance outcomes; 49 for externalizing behavior outcomes) extracted from 31 reports were included in the meta-analysis using robust variance estimation to handle dependencies among effect sizes. Mean effects were small and non-significant for attendance and externalizing behaviors. 

A moderate to large amount of heterogeneity was present; however, no moderator variable tested explained the variance between studies. Significant methodological shortcomings were identified across the corpus of studies included in this review. Implications for practice, policy and research are discussed.
AD  - [Kremer, Kristen P.; Maynard, Brandy R.; Vaughn, Michael G.] St Louis Univ, Sch Social Work, Coll Publ Hlth &amp; Social Justice, St Louis, MO 63103 USA. [Polanin, Joshua R.] Vanderbilt Univ, Peabody Res Inst, Nashville, TN 37203 USA. [Sarteschi, Christine M.] Chatham Univ, Dept Social Work &amp; Criminol, Pittsburgh, PA 15232 USA. Kremer, KP (reprint author), St Louis Univ, Sch Social Work, Coll Publ Hlth &amp; Social Justice, 3550 Lindell Blvd, St Louis, MO 63103 USA. kpeter26@slu.edu
AN  - WOS:000349605600005
AU  - Kremer,
AU  - K.
AU  - P.
AU  - Maynard,
AU  - B.
AU  - R.
AU  - Polanin,
AU  - J.
AU  - R.
AU  - Vaughn,
AU  - M.
AU  - G.
AU  - Sarteschi,
AU  - C.
AU  - M.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
J2  - J. Youth Adolesc.
KW  - After-school programs
KW  - Attendance
KW  - Externalizing behaviors
KW  - Systematic
KW  - review
KW  - Meta-analysis
KW  - learning-centers program
KW  - low-income children
KW  - intervention research
KW  - national evaluation
KW  - middle school
KW  - substance use
KW  - adolescents
KW  - students
KW  - bias
KW  - dissertations
KW  - Psychology
L1  - internal-pdf://3736612678/Kremer-2015-Effects of After-School Programs w.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: CB4NW Times Cited: 4 Cited Reference Count: 89 Kremer, Kristen P. Maynard, Brandy R. Polanin, Joshua R. Vaughn, Michael G. Sarteschi, Christine M. Maynard, Brandy/0000-0002-9356-7318 Nichd nih hhs [p50 hd052117] 4 6 84 Springer/plenum publishers New york 1573-6601
PY  - 2015
SP  - 616-636
T2  - Journal of Youth and Adolescence
TI  - Effects of After-School Programs with At-Risk Youth on Attendance and Externalizing Behaviors: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000349605600005
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597889/pdf/nihms723883.pdf
VL  - 44
ER  -
TY  - JOUR
AB  - **Background:** 
Infants born preterm are at increased risk of developing cognitive and motor impairment compared with infants born at term. Early developmental interventions have been provided in the clinical setting with the aim of improving overall functional outcomes for these infants. Long-term benefits of these programmes remain unclear.

**Objectives:** 
Primary objective: To compare the effectiveness of early developmental intervention programmes provided post hospital discharge to prevent motor or cognitive impairment in preterm (&lt; 37 weeks) infants versus standard medical follow-up of preterm infants at infancy (zero to &lt; three years), preschool age (three to &lt; five years), school age (five to &lt; 18 years) and adulthood (? 18 years). Secondary objectives: To perform subgroup analyses to determine the following.? Effects of gestational age, birth weight and brain injury (periventricular leukomalacia (PVL)/intraventricular haemorrhage (IVH)) on cognitive and motor outcomes when early intervention is compared with standard follow-up. ? Gestational age: &lt; 28 weeks, 28 to &lt; 32 weeks, 32 to &lt; 37 weeks. ? Birth weight: &lt; 1000 grams, 1000 to &lt; 1500 grams, 1500 to &lt; 2500 grams. ? Brain injury: absence or presence of grade III or grade IV IVH or cystic PVL (or both) or an abnormal ultrasound/magnetic resonance image (MRI) before initiation of the intervention.? Effects of interventions started during inpatient stay with a post-discharge component versus standard follow-up care.? Effects of interventions focused on the parent-infant relationship, infant development or both compared with standard follow-up care.To perform sensitivity analysis to identify the following.? Effects on motor and cognitive impairment when early developmental interventions are provided within high-quality randomised trials with low risk of bias for sequence generation, allocation concealment, blinding of outcome measures and selective reporting bias.

**Search methods:** 
The search strategy of the Cochrane Neonatal Review Group was used to identify randomised and quasi-randomised controlled trials of early developmental interventions provided post hospital discharge. Two review authors independently searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE Advanced, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO and EMBASE (1966 to August 2015).

**Selection criteria:** 
Studies included had to be randomised or quasi-randomised controlled trials of early developmental intervention programmes that began within the first 12 months of life for infants born before 37 weeks&#039; gestational age. Interventions could commence on an inpatient basis but had to include a post-discharge component for inclusion in this review. Outcome measures were not prespecified, other than that they had to assess cognitive outcomes, motor outcomes or both. Rates of cerebral palsy were documented.

**Data collection and analysis:** 
Two independent review authors extracted and entered data. Cognitive and motor outcomes were pooled by four age groups: infancy (zero to &lt; three years), preschool age (three to &lt; five years), school age (five to &lt; 18 years) and adulthood (? 18 years). Meta-analysis using RevMan 5.1 was carried out to determine the effects of early developmental interventions at each age range. Subgroup analyses focused on gestational age, birth weight, brain injury, commencement of the intervention, focus of the intervention and study quality.

**Main results:** 
Twenty-five studies met the inclusion criteria (3615 randomly assigned participants). Only 12 of these studies were randomised controlled trials with appropriate allocation concealment. Variability was evident with regard to focus and intensity of the intervention, participant characteristics and length of follow-up. Meta-analysis led to the conclusion that intervention improved cognitive outcomes at infancy (developmental quotient (DQ): standardised mean difference (SMD) 0.32 standard deviations (SDs), 95% confidence interval (CI) 0.16 to 0.47; P value &lt; 0.001; 16 studies; 2372 participa ts) and at preschool age (intelligence quotient (IQ); SMD 0.43 SDs, 95% CI 0.32 to 0.54; P value &lt; 0.001; eight studies; 1436 participants). However, this effect was not sustained at school age (IQ: SMD 0.18 SDs, 95% CI -0.08 to 0.43; P value = 0.17; five studies; 1372 participants). Heterogeneity between studies for cognitive outcomes at infancy and at school age was significant. With regards to motor outcomes, meta-analysis of 12 studies showed a significant effect in favour of early developmental interventions at infancy only; however, this effect was small (motor scale DQ: SMD 0.10 SDs, 95% CI 0.01 to 0.19; P value = 0.03; 12 studies; 1895 participants). No effect was noted on the rate of cerebral palsy among survivors (risk ratio (RR) 0.82, 95% CI 0.52 to 1.27; seven studies; 985 participants). Little evidence showed a positive effect on motor outcomes in the long term, but only five included studies reported outcomes at preschool age (n = 3) or at school age (n = 2).

**Authors&#039; conclusions:** 
Early intervention programmes for preterm infants have a positive influence on cognitive and motor outcomes during infancy, with cognitive benefits persisting into preschool age. A great deal of heterogeneity between studies was due to the variety of early developmental intervention programmes tested and to gestational ages of included preterm infants; thus, comparisons of intervention programmes were limited. Further research is needed to determine which early developmental interventions are most effective in improving cognitive and motor outcomes, and to discern the longer-term effects of these programmes.
AN  - CD005495
AU  - Spittle,
AU  - A.
AU  - Orton,
AU  - J.
AU  - Anderson,
AU  - P.
AU  - J.
AU  - Boyd,
AU  - R.
AU  - Doyle,
AU  - L.
AU  - W.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd005495.pub4
KW  - Birth Weight
KW  - Cerebral Palsy [prevention &amp; control]
KW  - Cognition Disorders [prevention &amp; control]
KW  - Early Intervention (Education) [methods]
KW  - Gestational Age
KW  - Infant, Premature
KW  - Infant, Premature, Diseases [prevention &amp; control]
KW  - Motor Skills Disorders [prevention &amp; control]
KW  - Movement Disorders [prevention &amp; control]
KW  - Patient Discharge
KW  - Psychomotor Disorders [prevention &amp; control]
KW  - Randomized Controlled Trials as Topic
KW  - Humans[checkword]
KW  - Infant, Newborn[checkword]
PY  - 2015
T2  - Cochrane Database of Systematic Reviews
TI  - Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005495.pub4/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005495.pub4/asset/CD005495.pdf?v=1&amp;t=iw7jbdgd&amp;s=b8ec823daf2240c1161acb63af5eb9ff488e2e53
ER  -
TY  - JOUR
AB  - Three-tiered models of prevention are increasingly being adopted by schools to address the behavioral needs of students. 

A critical component of multitiered systems are secondary interventions used with students in need of behavioral support but who are not candidates for individualized interventions. 

Despite the importance of secondary interventions, questions remain regarding which approaches have sufficient empirical support to warrant their use. 

The purpose of this review was, therefore, to examine the research underlying the Check-In/Check-Out (CICO) program, a widely used secondary intervention, to determine the strengths, limitations, and generality of the accumulated research. 

The What Works Clearinghouse (WWC) procedures for evaluating single-case and group-based research were applied with results indicating mixed support for the program. 

Specifically, there were a sufficient number of single-case research studies to deem the CICO program as evidence-based, while the group-based research had no demonstrated effects. 

These findings are discussed in terms of future research on the CICO program and the broader implications for selecting and implementing secondary interventions in school settings. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Maggin, Daniel M.: dan.m.maggin@gmail.com Maggin, Daniel M.: University of Illinois at Chicago, 1040 W Harrison St., Chicago, IL, US, 60607, dan.m.maggin@gmail.com Maggin, Daniel M.: University of Illinois at Chicago, Chicago, IL, US Zurheide, Jamie: University of Illinois at Chicago, Chicago, IL, US Pickett, Kayci C.: University of Illinois at Chicago, Chicago, IL, US Baillie, Sara J.: University of Illinois at Chicago, Chicago, IL, US
AN  - 2015-40173-002
AU  - Maggin,
AU  - D.
AU  - M.
AU  - Zurheide,
AU  - J.
AU  - Pickett,
AU  - K.
AU  - C.
AU  - Baillie,
AU  - S.
AU  - J.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1098300715573630
DP  - Ovid Technologies
KW  - check-in/check-out, evidence-based practice, positive behavioral interventions and supports, secondary interventions, systematic review
KW  - *Behavior Analysis
KW  - *Educational Programs
KW  - *Evidence Based Practice
KW  - *School Based Intervention
KW  - Educational/Vocational Counseling &amp; Student Services [3580]
KW  - Human
L1  - internal-pdf://1897685612/Maggin et al. (2015). A systematic evdence rev.pdf
LA  - English
M3  - Empirical Study; Literature Review; Systematic Review; Qualitative Study
PY  - 2015
SP  - 197-208
T2  - Journal of Positive Behavior Interventions
TI  - A systematic evidence review of the check-in/check-out program for reducing student challenging behaviors
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc12&amp;AN=2015-40173-002http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1098300715573630&amp;issn=1098-3007&amp;isbn=&amp;volume=17&amp;issue=4&amp;spage=197&amp;pages=197-208&amp;date=2015&amp;title=Journal+of+Positive+Behavior+Interventions&amp;atitle=A+systematic+evidence+review+of+the+check-in%2Fcheck-out+program+for+reducing+student+challenging+behaviors.&amp;aulast=Maggin&amp;pid=%3Cauthor%3EMaggin%2C+Daniel+M%3C%2Fauthor%3E%3CAN%3E2015-40173-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 17
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
Youth drug use is a severe problem worldwide. Usage of cannabis, amphetamine ecstasy and cocaine, referred to here as non-opioid drugs, are strongly associated with a range of health and social problems. Functional Family Therapy (FFT) is a short-term, manual-based, behaviorally oriented family therapy program for young people with behavior problems such as drug abuse, juvenile delinquency and violence. Delivered in an outpatient setting, it aims to help young people and their families by improving family interactions and relationship functioning by addressing dysfunctional individual behavior. As with many other forms of family therapy, FFT targets young people and their families as a system. As such, it recognizes the important role of the family system in the development and treatment of young people&rsquo;s drug abuse problems. 

**OBJECTIVES** 
The main aim of this review is to evaluate the current evidence on the effects of FFT on drug abuse reduction for young people in treatment for non-opioid drug use. 

**SEARCH METHODS** 
A wide range of electronic bibliographic databases were searched using a relatively narrow search strategy, in July 2013. We performed extensive searches in a broad selection of government and policy databanks, grey literature databases, citations in other reviews and included primary studies, and by hand searches of relevant journals and internet searches using Google. We also corresponded with researchers in the field of FFT. No language or date restrictions were applied to the searches. 

**SELECTION CRITERIA** 
To be eligible for inclusion, studies must have: &bull; involved a manual-based outpatient FFT treatment for young people aged 11-21 years enrolled for non-opioid drug use; &bull; used experimental, quasi-experimental or non-randomized controlled designs; &bull; reported at least one eligible outcome variable measuring abstinence, reduction of drug use, family functioning, education or vocational involvement, retention, risk behavior or other adverse effects; &bull; not focused exclusively on treating mental disorders; and &bull; had FFT as the primary intervention. 

**DATA COLLECTION AND ANALYSIS**
The literature search yielded a total of 6,719 records, which were screened for eligibility based on title and abstract. From these, 108 potentially relevant records were retrieved and screened in full text, of which 9 records were potentially relevant. Finally, two studies based on three records were included in the review. Meta-analysis was not possible because only one study provided numerical results on the effect of FFT on drug use reduction. RESULTS Two studies were included and both analyzed relative effects, comparing FFT to other interventions. Only one study provided numerical results on drug use reduction comparing FFT to two other interventions (CBT and a group intervention). The reported results indicate a positive effect favoring FFT on drug use frequency at 4-month follow up, with no statistically significant difference at 7-month follow up.

**AUTHORS&rsquo; CONCLUSIONS**
There is insufficient firm evidence to allow any conclusion to be drawn on the effect of FFT for young people in treatment for non-opioid drug use. There is a need for more research, and particularly for more methodologically rigorous studies in the field of treatment for young drug users. The aim of this systematic review was to explore what is known about the effectiveness of FFT for the purpose of reducing youth drug use. The evidence found does not provide a basis for drawing conclusions about actual outcomes and impacts. Consequently, no substantive conclusion on the effectiveness can be made, neither supporting nor rejecting of the present FFT treatment approach.
AU  - Filges,
AU  - T.
AU  - Andersen,
AU  - D.
AU  - Jørgensen,
AU  - A.
AU  - M.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2015.14
PY  - 2015
T2  - Campbell Systematic Reviews
TI  - Functional Family Therapy (FFT) for Young People in Treatment for Non-Opioid Drug Use: A Systematic Review
ER  -
TY  - JOUR
AB  - The birth of a premature infant can have adverse effects on the mood of mothers and on the interaction patterns between parents and their preterm babies. 

The aim of the present systematic review was to examine whether the Kangaroo Mother Care (KMC) intervention can attenuate these adverse psychological effects of a premature birth by ameliorating negative maternal mood and/or promoting more positive interactions between preterm infants and their parents. 

The results showed that although findings of studies were inconclusive, there is some evidence to suggest that KMC can make a positive difference on these areas. 

Specifically, it was found that KMC can improve negative maternal mood (e.g., anxiety or depression) and promote more positive parent-child interactions. 

Limitations and directions for future research are discussed. 

Copyright &copy; 2014 Michigan Association for Infant Mental Health.
AD  - Athanasopoulou,Eirini. Lancaster University, United Kingdom.
AN  - 25798479
AU  - Athanasopoulou,
AU  - E.
AU  - Fox,
AU  - J.
AU  - R.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/imhj.21444
DP  - Ovid Technologies
J2  - Infant Ment Health J
L1  - internal-pdf://3581143112/Athanasopoulou-2014-Effects of kangaroo mother.pdf
LA  - English
N1  - Athanasopoulou, Eirini Fox, John R E
PY  - 2014
SP  - 245-62
T2  - Infant Mental Health Journal
TI  - Effects of kangaroo mother care on maternal mood and interaction patterns between parents and their preterm, low birth weight infants: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25798479
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25798479&amp;id=doi:10.1002%2Fimhj.21444&amp;issn=0163-9641&amp;isbn=&amp;volume=35&amp;issue=3&amp;spage=245&amp;pages=245-62&amp;date=2014&amp;title=Infant+Mental+Health+Journal&amp;atitle=Effects+of+kangaroo+mother+care+on+maternal+mood+and+interaction+patterns+between+parents+and+their+preterm%2C+low+birth+weight+infants%3A+a+systematic+review.&amp;aulast=Athanasopoulou&amp;pid=%3Cauthor%3EAthanasopoulou+E%3C%2Fauthor%3E%3CAN%3E25798479%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1002/imhj.21444/asset/imhj21444.pdf?v=1&amp;t=ib3by4kf&amp;s=d1e43b25f994e01ee0184de64347d04713976e2d
UR  - http://onlinelibrary.wiley.com/store/10.1002/imhj.21444/asset/imhj21444.pdf?v=1&amp;t=j8yey7uj&amp;s=277406ebdacbd957d2dd71a3a61dd9a7a9749f37
VL  - 35
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
We undertook a meta-analysis of published Randomized Controlled Trials (RCT) with semi-active control and sham-NF groups to determine whether Electroencephalogram-neurofeedback (EEG-NF) significantly improves the overall symptoms, inattention and hyperactivity/impulsivity dimensions for probably unblinded assessment (parent assessment) and probably blinded assessment (teacher assessment) in children with Attention Deficit Hyperactivity Disorder (ADHD). 

**DATA SOURCES: **
A systematic review identified independent studies that were eligible for inclusion in a random effects meta-analysis. 

**DATA EXTRACTION: **
Effect sizes for ADHD symptoms were expressed as standardized mean differences (SMD) with 95% confidence intervals. 

**RESULTS: **
Five identified studies met eligibility criteria, 263 patients with ADHD were included, 146 patients were trained with EEG-NF. On parent assessment (probably unblinded assessment), the overall ADHD score (SMD = -0.49 [-0.74, -0.24]), the inattention score (SMD = -0.46 [-0.76, -0.15]) and the hyperactivity/impulsivity score (SMD = -0.34 [-0.59, -0.09]) were significantly improved in patients receiving EEG-NF compared to controls. On teacher assessment (probably blinded assessment), only the inattention score was significantly improved in patients receiving EEG-NF compared to controls (SMD = -0.30 [-0.58, -0.03]). 

CONCLUSIONS: 
This meta-analysis of EEG-NF in children with ADHD highlights improvement in the inattention dimension of ADHD symptoms. Future investigations should pay greater attention to adequately blinded studies and EEG-NF protocols that carefully control the implementation and embedding of training.
AD  - Micoulaud-Franchi,Jean-Arthur. Solaris, Unite de Neurophysiologie, Pole de Psychiatrie Universitaire, Hopital Sainte-Marguerite Marseille, France ; Institut de Neurosciences Cognitives de la Mediterranee, INCM-CNRS UMR 6193 Marseille, France. Geoffroy,Pierre Alexis. Inserm, UMR-S 1144 Paris, France ; AP-HP, GH Saint-Louis - Lariboisiere - Fernand Widal, Pole Neurosciences Paris, France ; UMR-S 1144, Universite Paris Descartes and Universite Paris Diderot Paris, France ; Fondation FondaMental Creteil, France. Fond,Guillaume. Fondation FondaMental Creteil, France ; Universite Paris Est-Creteil, Pole de Psychiatrie du Groupe des Hopitaux Universitaires de Mondor, DHU Pe-psy, INSERM U955, Eq Psychiatrie Genetique, Reseau des Centres Experts Schizophrenie de France Creteil, France. Lopez,Regis. Centre de Reference National Narcolepsie-hypersomnie Idiopathique, Unite des Troubles du Sommeil, CHU Gui de Chauliac Montpellier, France ; NSERM U1061 Montpellier, France. Bioulac,Stephanie. Centre Hospitalier Charles Perrens, Pole Universitaire de Psychiatrie de l&#039;Enfant et de l&#039;Adolescent Bordeaux, France ; USR CNRS 3413 SANPSY, Clinique du Sommeil, CHU Pellegrin, Universite de Bordeaux Bordeaux, France. Philip,Pierre. USR CNRS 3413 SANPSY, Clinique du Sommeil, CHU Pellegrin, Universite de Bordeaux Bordeaux, France.
AN  - 25431555
AU  - Micoulaud-Franchi,
AU  - J.
AU  - A.
AU  - Geoffroy,
AU  - P.
AU  - A.
AU  - Fond,
AU  - G.
AU  - Lopez,
AU  - R.
AU  - Bioulac,
AU  - S.
AU  - Philip,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3389/fnhum.2014.00906
DP  - Ovid Technologies
J2  - Front Hum Neurosci
L1  - internal-pdf://0407455734/Micoulaud-Franc-2014-EEG neurofeedback treatme.pdf
LA  - English
M3  - Review
N1  - Micoulaud-Franchi, Jean-Arthur Geoffroy, Pierre Alexis Fond, Guillaume Lopez, Regis Bioulac, Stephanie Philip, Pierre
PY  - 2014
SP  - 906
T2  - Frontiers in Human Neuroscience
TI  - EEG neurofeedback treatments in children with ADHD: an updated meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25431555 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25431555&amp;id=doi:10.3389%2Ffnhum.2014.00906&amp;issn=1662-5161&amp;isbn=&amp;volume=8&amp;issue=&amp;spage=906&amp;pages=906&amp;date=2014&amp;title=Frontiers+in+Human+Neuroscience&amp;atitle=EEG+neurofeedback+treatments+in+children+with+ADHD%3A+an+updated+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Micoulaud-Franchi&amp;pid=%3Cauthor%3EMicoulaud-Franchi+JA%3C%2Fauthor%3E%3CAN%3E25431555%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230047/pdf/fnhum-08-00906.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230047/pdf/fnhum-08-00906.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - The purpose of this research was to update the Pelham and Fabiano (2008) review of evidence-based practices for children and adolescents with attention-deficit/hyperactivity disorder. We completed a systematic review of the literature published between 2007 and 2013 to establish levels of evidence for psychosocial treatments for these youth. 

Our review included the identification of relevant articles using criteria established by the Society of Clinical Child and Adolescent Psychology (see Southam-Gerow &amp; Prinstein, in press) using keyword searches and a review of tables of contents. We extend the conceptualization of treatment research by differentiating training interventions from behavior management and by reviewing the growing literature on training interventions. 

Consistent with the results of the previous review we conclude that behavioral parent training, behavioral classroom management, and behavioral peer interventions are well-established treatments. 

In addition, organization training met the criteria for a well-established treatment. Combined training programs met criteria for Level 2 (Probably Efficacious), neurofeedback training met criteria for Level 3 (Possibly Efficacious), and cognitive training met criteria for Level 4 (Experimental Treatments). 

The distinction between behavior management and training interventions provides a method for considering meaningful differences in the methods and possible mechanisms of action for treatments for these youth. 

Characteristics of treatments, participants, and measures, as well as the variability in methods for classifying levels of evidence for treatments, are reviewed in relation to their potential effect on outcomes and conclusions about treatments. Implications of these findings for future science and practice are discussed.
AD  - [Evans, Steven W.; Owens, Julie Sarno; Bunford, Nora] Ohio Univ, Dept Psychol, Athens, OH 45701 USA. Evans, SW (reprint author), Ohio Univ, Dept Psychol, Ctr Intervent Res Sch, Porter Hall, Athens, OH 45701 USA. evanss3@ohio.edu
AN  - WOS:000340120200001
AU  - Evans,
AU  - S.
AU  - W.
AU  - Owens,
AU  - J.
AU  - S.
AU  - Bunford,
AU  - N.
DA  - Jul-Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/15374416.2013.850700
J2  - J. Clin. Child Adolesc. Psychol.
KW  - DEFICIT HYPERACTIVITY DISORDER EVIDENCE-BASED INTERVENTIONS RANDOMIZED CLINICAL-TRIAL POSSIBLE CHANGES MODEL AFTER-SCHOOL PROGRAM BEHAVIORAL TREATMENT TREATMENT RESPONSE SYMPTOM REPORTS YOUNG-CHILDREN MIDDLE SCHOOL Psychology, Clinical Psychology, Devel
L1  - internal-pdf://2672747256/Evans-2014-Evidence-Based Psychosocial Treatme.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AM8JM Times Cited: 12 Cited Reference Count: 67 Evans, Steven W. Owens, Julie Sarno Bunford, Nora 12 ROUTLEDGE JOURNALS, TAYLOR &amp; FRANCIS LTD ABINGDON J CLIN CHILD ADOLESC
PY  - 2014
SP  - 527-551
T2  - Journal of Clinical Child and Adolescent Psychology
TI  - Evidence-Based Psychosocial Treatments for Children and Adolescents with Attention-Deficit/Hyperactivity Disorder
UR  - &lt;Go to ISI&gt;://WOS:000340120200001http://www.tandfonline.com/doi/pdf/10.1080/15374416.2013.850700
UR  - http://www.tandfonline.com/doi/pdf/10.1080/15374416.2013.850700?needAccess=true
VL  - 43
ER  -
TY  - JOUR
AB  - **Background:** 
The World Health Organization&#039;s (WHO?s) Health Promoting Schools (HPS) framework is an holistic, settings-based approach to promoting health and educational attainment in school. The effectiveness of this approach has not been previously rigorously reviewed.

**Objectives:** 
To assess the effectiveness of the Health Promoting Schools (HPS) framework in improving the health and well-being of students and their academic achievement.

**Search methods:** 
We searched the following electronic databases in January 2011 and again in March and April 2013: Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, PsycINFO, CINAHL, Campbell Library, ASSIA, BiblioMap, CAB Abstracts, IBSS, Social Science Citation Index, Sociological Abstracts, TRoPHI, Global Health Database, SIGLE, Australian Education Index, British Education Index, Education Resources Information Centre, Database of Education Research, Dissertation Express, Index to Theses in Great Britain and Ireland, ClinicalTrials.gov, Current controlled trials, and WHO International Clinical Trials Registry Platform. We also searched relevant websites, handsearched reference lists, and used citation tracking to identify other relevant articles.

**Selection criteria:** 
We included cluster-randomised controlled trials where randomisation took place at the level of school, district or other geographical area. Participants were children and young people aged four to 18 years, attending schools or colleges. In this review, we define HPS interventions as comprising the following three elements: input to the curriculum; changes to the school?s ethos or environment or both; and engagement with families or communities, or both. We compared this intervention against schools that implemented either no intervention or continued with their usual practice, or any programme that included just one or two of the above mentioned HPS elements.

**Data collection and analysis:** 
At least two review authors identified relevant trials, extracted data, and assessed risk of bias in the trials. We grouped different types of interventions according to the health topic targeted or the approach used, or both. Where data permitted, we performed random-effects meta-analyses to provide a summary of results across studies.

**Main results:** 
We included 67 eligible cluster trials, randomising 1443 schools or districts. This is made up of 1345 schools and 98 districts. The studies tackled a range of health issues: physical activity (4), nutrition (12), physical activity and nutrition combined (18), bullying (7), tobacco (5), alcohol (2), sexual health (2), violence (2), mental health (2), hand-washing (2), multiple risk behaviours (7), cycle-helmet use (1), eating disorders (1), sun protection (1), and oral health (1). The quality of evidence overall was low to moderate as determined by the GRADE approach. &#039;Risk of bias&#039; assessments identified methodological limitations, including heavy reliance on self-reported data and high attrition rates for some studies. In addition, there was a lack of long-term follow-up data for most studies.We found positive effects for some interventions for: body mass index (BMI), physical activity, physical fitness, fruit and vegetable intake, tobacco use, and being bullied. Intervention effects were generally small but have the potential to produce public health benefits at the population level. We found little evidence of effectiveness for standardised body mass index (zBMI) and no evidence of effectiveness for fat intake, alcohol use, drug use, mental health, violence and bullying others; however, only a small number of studies focused on these latter outcomes. It was not possible to meta-analyse data on other health outcomes due to lack of data. Few studies provided details on adverse events or outcomes related to the interventions. In addition, few studies included any academic, attendance or school-related outcomes. We therefore cannot draw any clear conclusions as to the effectiveness of this approach for improving academic achievement.

**Authors&#039; conclusions:**
The result f this review provide evidence for the effectiveness of some interventions based on the HPS framework for improving certain health outcomes but not others. More well-designed research is required to establish the effectiveness of this approach for other health topics and academic achievement.
AN  - CD008958
AU  - Langford,
AU  - R.
AU  - Bonell,
AU  - C.
AU  - P.
AU  - Jones,
AU  - H.
AU  - E.
AU  - Pouliou,
AU  - T.
AU  - Murphy,
AU  - S.
AU  - M.
AU  - Waters,
AU  - E.
AU  - Komro,
AU  - K.
AU  - A.
AU  - Gibbs,
AU  - L.
AU  - F.
AU  - Magnus,
AU  - D.
AU  - Campbell,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd008958.pub2
KW  - Achievement
KW  - Health Behavior
KW  - School Health Services
KW  - Students
KW  - World Health Organization
KW  - Bullying
KW  - Health Promotion [methods]
KW  - Mental Health
KW  - Motor Activity
KW  - Obesity [prevention &amp; control]
KW  - Randomized Controlled Trials as Topic
KW  - Reproductive Health
KW  - Substance-Related Disorders [prevention &amp; control]
KW  - Violence
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2014
T2  - Cochrane Database of Systematic Reviews
TI  - The WHO Health Promoting School framework for improving the health and well-being of students and their academic achievement
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008958.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD008958.pub2/asset/CD008958.pdf?v=1&amp;t=iw7lemug&amp;s=9c4e9392f8fa8289beae6c183e4434cf7f64df86
ER  -
TY  - JOUR
AB  - Pediatric depression entails a higher risk for psychiatric disorders, somatic complaints, suicide, and functional impairment later in life. 

Cognitive behavior therapy (CBT) is recommended for the treatment of depression in children, yet research is based primarily on adolescents. The present meta-analysis investigated the efficacy of CBT in children aged 8-12 years with regard to depressive symptoms. 

We included randomized controlled trials of CBT with participants who had an average age of &lt; 12 years and were diagnosed with either depression or reported elevated depressive symptoms. 

The search resulted in 10 randomized controlled trials with 267 participants in intervention and 256 in comparison groups. The mean age of participants was 10.5 years. The weighted between-group effect size for CBT was moderate, Cohen&#039;s d = 0.66. CBT outperformed both attention placebo and wait-list, although there was a significant heterogeneity among studies with regard to effect sizes. 

The weighted within-group effect size for CBT was large, d = 1.02. Earlier publication year, older participants, and more treatment sessions were associated with a larger effect size. 

In conclusion, the efficacy of CBT in the treatment of pediatric depression symptoms was supported. Differences in efficacy, methodological shortcomings, and lack of follow-up data limit the present study and indicate areas in need of improvement.
AD  - Arnberg,Alexandra. a Department of Psychology , Stockholm University , Stockholm , Sweden.
AN  - 25248459
AU  - Arnberg,
AU  - A.
AU  - Ost,
AU  - L.
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/16506073.2014.947316
DP  - Ovid Technologies
J2  - Cognitive Behav Ther
L1  - internal-pdf://0768869461/Arnberg-2014-CBT for children with depressive.pdf
LA  - English
N1  - Arnberg, Alexandra Ost, Lars-Goran
PY  - 2014
SP  - 275-88
T2  - Cognitive Behaviour Therapy
TI  - CBT for children with depressive symptoms: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25248459 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25248459&amp;id=doi:10.1080%2F16506073.2014.947316&amp;issn=1650-6073&amp;isbn=&amp;volume=43&amp;issue=4&amp;spage=275&amp;pages=275-88&amp;date=2014&amp;title=Cognitive+Behaviour+Therapy&amp;atitle=CBT+for+children+with+depressive+symptoms%3A+a+meta-analysis.&amp;aulast=Arnberg&amp;pid=%3Cauthor%3EArnberg+A%3C%2Fauthor%3E%3CAN%3E25248459%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/16506073.2014.947316
UR  - http://www.tandfonline.com/doi/pdf/10.1080/16506073.2014.947316?needAccess=true
VL  - 43
ER  -
TY  - JOUR
AB  - This article updates the evidence base on outpatient behavioral treatments for adolescent substance use (ASU) since publication of the previous review completed for this journal by Waldron and Turner ( 2008 ). 

It first summarizes the Waldron and Turner findings as well as those from more recent literature reviews and meta-analytic studies of ASU treatment. It then presents study design and methods criteria used to select 19 comparative studies subjected to Journal of Clinical Child &amp; Adolescent Psychology level of support evaluation. 

These 19 studies are grouped by study category (efficacy or effectiveness) and described for sample characteristics, methodological quality, and substance use outcomes. Cumulative level of support designations are then made for each identified treatment approach: ecological family-based treatment, group cognitive-behavioral therapy, and individual cognitive-behavioral therapy are deemed Well Established; behavioral family-based treatment and motivational interviewing are deemed Probably Efficacious; drug counseling is deemed Possibly Efficacious; and four integrated treatment models combining more than one approach are deemed Well Established or Probably Efficacious. 

The remainder of the article (a) articulates fidelity, mediator, and moderator effects reported for evidence-based approaches since 2008 and (b) recommends four enhancements to the prevailing business model of ASU outpatient services to accelerate penetration of evidence-based approaches into the underserved consumer base: pursue partnerships with influential governmental systems, utilize web-based technology to extend reach and control costs, adapt effective methods for linking services across sectors of care, and promote uptake and sustainability by emphasizing return on investment.
AD  - Hogue,Aaron. a The National Center on Addiction and Substance Abuse at Columbia University.
AN  - 24926870
AU  - Hogue,
AU  - A.
AU  - Henderson,
AU  - C.
AU  - E.
AU  - Ozechowski,
AU  - T.
AU  - J.
AU  - Robbins,
AU  - M.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15374416.2014.915550
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
KW  - Adolescent *Ambulatory Care *Behavior Therapy/mt [Methods] *Evidence-Based Medicine Humans Practice Guidelines as Topic *Substance-Related Disorders/th [Therapy]
LA  - English
M3  - Meta-Analysis Review
N1  - Hogue, Aaron Henderson, Craig E Ozechowski, Timothy J Robbins, Michael S
PY  - 2014
SP  - 695-720
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Evidence base on outpatient behavioral treatments for adolescent substance use: updates and recommendations 2007-2013
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24926870
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24926870&amp;id=doi:10.1080%2F15374416.2014.915550&amp;issn=1537-4416&amp;isbn=&amp;volume=43&amp;issue=5&amp;spage=695&amp;pages=695-720&amp;date=2014&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Evidence+base+on+outpatient+behavioral+treatments+for+adolescent+substance+use%3A+updates+and+recommendations+2007-2013.&amp;aulast=Hogue&amp;pid=%3Cauthor%3EHogue+A%3C%2Fauthor%3E%3CAN%3E24926870%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/15374416.2014.915550
VL  - 43
ER  -
TY  - JOUR
AB  - Psychological treatments for obsessive-compulsive disorder (OCD) are increasingly aimed at improving outcomes by directly incorporating family members to address family disruption, dysfunction, or symptom accommodation. 

Much remains to be learned about the pooled effects of &quot;family inclusive treatment&quot; (FIT) for OCD and factors that may explain variation in response. Random-effects meta-analytic procedures were conducted to empirically evaluate the overall effect of FITs on OCD, and treatment moderators. 

Study search criteria yielded 29 studies examining FIT response in 1,366 OCD patients. Outcome variables included OCD symptoms and global functioning. Examined moderators included age group, gender, minority status, treatment length and format, and inclusion of specific family focused treatment elements. FITs for OCD demonstrated a large overall effect on OCD symptoms (pooled d = 1.68, SE = 0.14) and global functioning (pooled d = 0.98, SE = 0.14). 

Moderator analyses found that individual family treatments (vs. group) and FITs targeting family accommodation of symptoms (vs. those that did not target accommodation) were associated with greater improvements in patient functioning. 

Results indicate a robust overall response to FITs for OCD and clarify key moderators that inform optimal circumstances for effective treatment. Findings underscore the need for continued momentum in the development, evaluation, and dissemination of FITs for OCD. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Thompson-Hollands, Johanna: hollands@bu.edu Thompson-Hollands, Johanna: Boston University, 648 Beacon Street, Floor 6, Boston, MA, US, 02215, hollands@bu.edu Thompson-Hollands, Johanna: Department of Psychology, Boston University, Boston, MA, US Edson, Aubrey: Department of Psychology, Boston University, Boston, MA, US Tompson, Martha C.: Department of Psychology, Boston University, Boston, MA, US Comer, Jonathan S.: Department of Psychology, Florida International University, Miami, FL, US
AN  - 2014-15706-001
AU  - Thompson-Hollands,
AU  - J.
AU  - Edson,
AU  - A.
AU  - Tompson,
AU  - M.
AU  - C.
AU  - Comer,
AU  - J.
AU  - S.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1037/a0036709
DP  - Ovid Technologies
KW  - CBT, OCD, accommodation, family-based treatment, meta-analysis, obsessive-compulsive disorder, cognitive-behavioral therapy *Cognitive Behavior Therapy *Family Therapy *Obsessive Compulsive Disorder Cognitive Therapy [3311] Human Adolescence (13-17 yrs)
LA  - English
M3  - Meta Analysis
PY  - 2014
SP  - 287-298
T2  - Journal of Family Psychology
TI  - Family involvement in the psychological treatment of obsessive-compulsive disorder: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2014-15706-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2Fa0036709&amp;issn=0893-3200&amp;isbn=&amp;volume=28&amp;issue=3&amp;spage=287&amp;pages=287-298&amp;date=2014&amp;title=Journal+of+Family+Psychology&amp;atitle=Family+involvement+in+the+psychological+treatment+of+obsessive-compulsive+disorder%3A+A+meta-analysis.&amp;aulast=Thompson-Hollands&amp;pid=%3Cauthor%3EThompson-Hollands%2C+Johanna%3C%2Fauthor%3E%3CAN%3E2014-15706-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://psycnet.apa.org/journals/fam/28/3/287.pdf
VL  - 28
ER  -
TY  - JOUR
AB  - Evaluation of evidence-based treatments is important for adolescents and adults with autism spectrum disorders (ASD) given the increasing number of interventions available and the prevalence of ASD. 

In this study, we sought to evaluate the effectiveness of behavioral interventions for this population by conducting a meta-analysis of published single-case research studies. A new metric for calculating effect size in single-case research, nonoverlap of all pairs, was utilized.

In addition, the certainty of evidence, a system to evaluate research methodology, was applied to the reviewed articles. Forty-three articles were identified in the study. 

Results suggested that the behavioral interventions in the areas of academic skills, adaptive skills, problem behavior, phobic avoidance, social skills, and vocational skills have medium-to-strong effect sizes. Medium-to-high confidence in findings was noted for 81 % of the studies in the meta-analysis; however, three-fourths of the reviewed studies did not include treatment integrity, which may affect the ability to draw conclusions about the effectiveness of the interventions. 

Overall, the evidence is promising for the use of behavioral interventions for this population; however, additional research and dissemination are needed to fill the gap between research and practice in order for practitioners to meet the increasing demand as individuals with ASD age. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Roth, Matthew E.: mer0012@auburn.edu Roth, Matthew E.: Department of Psychology, Auburn University, 226 Thach Hall, Auburn, AL, US, 36849, mer0012@auburn.edu Roth, Matthew E.: Department of Psychology, Auburn University, Auburn, AL, US Gillis, Jennifer M.: Department of Psychology, Auburn University, Auburn, AL, US DiGennaro Reed, Florence D.: Department of Applied Behavioral Science, University of Kansas, Lawrence, KS, US
AN  - 2013-44155-001
AU  - Roth,
AU  - M.
AU  - E.
AU  - Gillis,
AU  - J.
AU  - M.
AU  - DiGennaro
AU  - Reed,
AU  - F.
AU  - D.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10864-013-9189-x
DP  - Ovid Technologies
KW  - Adolescents, Adults, Autism spectrum disorders, Meta-analysis, Single-case research, Behavioral intervention, Evidence-based treatment, Treatment efficacy *Autism *Behavior Modification *Behavior Therapy *Intervention *Pervasive Developmental Disorders
LA  - English
M3  - Meta Analysis
PY  - 2014
SP  - 258-286
T2  - Journal of Behavioral Education
TI  - A meta-analysis of behavioral interventions for adolescents and adults with autism spectrum disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-44155-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10864-013-9189-x&amp;issn=1053-0819&amp;isbn=&amp;volume=23&amp;issue=2&amp;spage=258&amp;pages=258-286&amp;date=2014&amp;title=Journal+of+Behavioral+Education&amp;atitle=A+meta-analysis+of+behavioral+interventions+for+adolescents+and+adults+with+autism+spectrum+disorders.&amp;aulast=Roth&amp;pid=%3Cauthor%3ERoth%2C+Matthew+E%3C%2Fauthor%3E%3CAN%3E2013-44155-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10864-013-9189-xhttp://download.springer.com/static/pdf/887/art%253A10.1007%252Fs10864-013-9189-x.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10864-013-9189-x&amp;token2=exp=1435232106~acl=%2Fstatic%2Fpdf%2F887%2Fart%25253A10.1007%25252Fs10864-013-9189-x.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10864-013-9189-x*~hmac=39f4e54cb27e5b413656a68a9acd7450e50afbd8da2449dcc4891724e977b11b
VL  - 23
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Systematically review and synthesize the clinical evidence of treatments for attention deficit hyperactivity disorder (ADHD) by indirectly comparing established treatments in the UK with a drug recently approved in Europe (lisdexamfetamine [LDX]). Research design and methods: 

**POPULATION: **
Children and adolescents. 

**SETTING:** 
Europe. 

**Comparators: **
methylphenidate (MPH), atomoxetine (ATX), and dexamphetamine (DEX). Electronic databases and relevant conference proceedings were searched for randomized, controlled clinical trials evaluating efficacy and safety of at least one of the comparators and LDX. Quality assessments for each included trial were performed using criteria recommended by the Centre for Reviews and Dissemination. Network meta-analysis methods for dichotomous outcomes were employed to evaluate treatment efficacy. 

**MAIN OUTCOME MEASURES: **
Response, as defined by either a reduction from baseline of at least 25% in the ADHD Rating Scale [ADHD-RS] total score or, separately, as assessed on the Clinical Global Impression-Improvement [CGI-I] scale, and safety (all-cause withdrawals and withdrawal due to adverse events). 

**RESULTS: **
The systematic review found 32 trials for the meta-analysis, including data on LDX, ATX, and different formulations of MPH. No trials for DEX meeting the inclusion criteria were found. Sufficient data were identified for each outcome: ADHD-RS, 16 trials; CGI-I, 20 trials; all-cause withdrawals, 28 trials; and withdrawals due to adverse events, 27 trials. The relative probability of treatment response for CGI-I (95% confidence intervals [CI]) for ATX versus LDX was 0.65 (0.53-0.78); for long-acting MPH versus LDX, 0.82 (0.69-0.97); for intermediate release MPH versus LDX, 0.51 (0.40-0.65); and for short-acting MPH versus LDX, 0.62 (0.51-0.76). The relative probabilities of ADHD-RS treatment response also favored LDX. 

**CONCLUSIONS:** 
For the treatment of ADHD, the synthesis of efficacy data showed statistically significant better probabilities of response with LDX than for formulations of MPH or ATX. The analysis of safety data proved inconclusive due to low event rates. These results may be limited by the studies included, which only investigated the short-term efficacy of medications in patients without comorbid disorders.
AD  - Roskell,N S. BresMed Health Solutions , Sheffield , UK.
AN  - 24627974
AU  - Roskell,
AU  - N.
AU  - S.
AU  - Setyawan,
AU  - J.
AU  - Zimovetz,
AU  - E.
AU  - A.
AU  - Hodgkins,
AU  - P.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1185/03007995.2014.904772
DP  - Ovid Technologies
J2  - Curr Med Res Opin
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Roskell, N S Setyawan, J Zimovetz, E A Hodgkins, P
PY  - 2014
SP  - 1673-85
T2  - Current Medical Research &amp; Opinion
TI  - Systematic evidence synthesis of treatments for ADHD in children and adolescents: indirect treatment comparisons of lisdexamfetamine with methylphenidate and atomoxetine
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24627974 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24627974&amp;id=doi:10.1185%2F03007995.2014.904772&amp;issn=0300-7995&amp;isbn=&amp;volume=30&amp;issue=8&amp;spage=1673&amp;pages=1673-85&amp;date=2014&amp;title=Current+Medical+Research+%26+Opinion&amp;atitle=Systematic+evidence+synthesis+of+treatments+for+ADHD+in+children+and+adolescents%3A+indirect+treatment+comparisons+of+lisdexamfetamine+with+methylphenidate+and+atomoxetine.&amp;aulast=Roskell&amp;pid=%3Cauthor%3ERoskell+NS%3C%2Fauthor%3E%3CAN%3E24627974%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://informahealthcare.com/doi/pdfplus/10.1185/03007995.2014.904772
VL  - 30
ER  -
TY  - JOUR
AB  - **Background** 
With increasing survival estimates for individuals with cystic fibrosis, long-term management has become an important focus. Psychological interventions are largely concerned with adherence to treatment, emotional and social adaptation and health-related quality of life. We are unaware of any relevant systematic reviews. 

**Objectives **
To determine whether psychological interventions for people with cystic fibrosis provide significant psychosocial and physical benefits in addition to standard medical care. Search methods Studies were identified from two Cochrane trials registers (Cystic Fibrosis and Genetic Disorders Group; Depression, Anxiety and Neurosis Group), Ovid MEDLINE and PsychINFO; unpublished trials were located through professional networks and Listserves. Most recent search of the Cystic Fibrosis and Genetic Disorders Group&#039;s register: 19 December 2013. Most recent search of the Depression, Anxiety and Neurosis Group&#039;s register: 12 November 2013. 

**Selection criteria** 
Randomised controlled studies of a broad range of psychological interventions evaluating subjective and objective health outcomes, such as quality of life or pulmonary function, in individuals of all ages with cystic fibrosis and their immediate family. We were interested in psychological interventions, including psychological methods within the scope of psychotherapeutic or psychosomatic mechanism of action (e. g. cognitive behavioural, cognitive, family systems or systemic, psycho-dynamic, or other, e. g. supportive, relaxation, or biofeedback), which were aimed at improving psychological and psychosocial outcomes (e. g. quality of life, levels of stress or distress, psychopathology, etc.), adaptation to disease management and physiological outcomes. 

**Data collection and analysis** 
Three authors were involved in selecting the eligible studies and two of these authors assessed their risk of bias. 

**Main results **
The review includes 16 studies (eight new studies included in this update) representing data from 556 participants. Studies are diverse in their design and their methods. They cover interventions with generic approaches, as well as interventions developed specifically to target disease-specific symptoms and problems in people with cystic fibrosis. These include cognitive behavioural interventions to improve adherence to nutrition or psychosocial adjustment, cognitive interventions to improve adherence or those associated with decision making in lung transplantation, a community-based support intervention and other interventions, such as self-hypnosis, respiratory muscle biofeedback, music therapy, dance and movement therapy, and a tele-medicine intervention to support patients awaiting transplantation. A substantial proportion of outcomes relate to adherence, changes in physical status or other specific treatment concerns during the chronic phase of the disease. There is some evidence that behavioural interventions targeting nutrition and growth in children (4 to 12 years) with cystic fibrosis are effective in the short term. Evidence was found that providing a structured decision-making tool for patients considering lung transplantation improves patients&#039; knowledge of and expectations about the transplant, and reduces decisional conflict in the short term. One study about training in biofeedback-assisted breathing demonstrated some evidence that it improved some lung function measurements. Currently there is insufficient evidence for interventions aimed at other aspects of the disease process. 

**Authors&#039; conclusions** 
Currently, insufficient evidence exists on psychological interventions or approaches to support people with cystic fibrosis and their caregivers, although some of the studies were promising. Due to the heterogeneity between studies, more of each type of intervention are needed to support preliminary evidence. Multicentre studies, with consequent funding implications, are needed to increase the sample size of these studies and enhance the statistical power and precision to detect important findings. In addition, multicent e studies could improve the generalisation of results by minimizing centre or therapist effects. Psychological interventions should be targeted to illness-specific symptoms or behaviours to demonstrate efficacy.
AD  - [Goldbeck, Lutz; Fidika, Astrid; Herle, Marion] Univ Clin Ulm, Dept Child &amp; Adolescent Psychiat Psychotherapy, D-89075 Ulm, Baden Wurttembe, Germany. [Quittner, Alexandra L.] Univ Miami, Dept Psychol, Miami, FL USA. Goldbeck, L (reprint author), Univ Clin Ulm, Dept Child &amp; Adolescent Psychiat Psychotherapy, Steinhoevelstr 5, D-89075 Ulm, Baden Wurttembe, Germany. Lutz.Goldbeck@uniklinik-ulm.de
AN  - WOS:000338308700015
AU  - Goldbeck,
AU  - L.
AU  - Fidika,
AU  - A.
AU  - Herle,
AU  - M.
AU  - Quittner,
AU  - A.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD003148.pub3
J2  - Cochrane Database Syst Rev.
KW  - Caregivers [psychology] Cystic Fibrosis [ psychology therapy] Diet [psychology] Family Family Therapy [methods] Psychotherapy [methods] Randomized Controlled Trials as Topic Respiratory Therapy [psychology] Adult Child Humans QUALITY-OF-LIFE PROSPECTIVE
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AK3FM Times Cited: 0 Cited Reference Count: 217 Goldbeck, Lutz Fidika, Astrid Herle, Marion Quittner, Alexandra L. Royal Liverpool Children&#039;s NHS Trust, UK.; National Institutes of Health, USA. Internal sourcesRoyal Liverpool Children&#039;s NHS Trust, UK.National Institutes of Health, USA.External sourcesNo sources of support supplied WILEY-BLACKWELL HOBOKEN COCHRANE DB SYST REV
PY  - 2014
SP  - 156
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological interventions for individuals with cystic fibrosis and their families
UR  - &lt;Go to ISI&gt;://WOS:000338308700015http://onlinelibrary.wiley.com/store/10.1002/14651858.CD003148.pub3/asset/CD003148.pdf?v=1&amp;t=ib7th6uo&amp;s=949886abbef4370a18627fe48ab744536b669f3a
ER  -
TY  - JOUR
AB  - **Background:** 
The scientific literature examining effective treatments for opioid dependent adults clearly indicates that pharmacotherapy is a necessary and acceptable component of effective treatments for opioid dependence. Nevertheless, no studies have been published that systematically assess the effectiveness of the pharmacological detoxification among adolescents.

**Objectives:** 
To assess the effectiveness of any detoxification treatment alone or in combination with psychosocial intervention compared with no intervention, other pharmacological intervention or psychosocial interventions on completion of treatment, reducing the use of substances and improving health and social status.

**Search methods:** 
We searched the Cochrane Central Register of Controlled Trials (2014, Issue 1), PubMed (January 1966 to January 2014), EMBASE (January 1980 to January 2014), CINHAL (January 1982 to January 2014), Web of Science (1991-January 2014) and reference lists of articles.

**Selection criteria:** 
Randomised controlled clinical trials comparing any pharmacological interventions alone or associated with psychosocial intervention aimed at detoxification with no intervention, placebo, other pharmacological intervention or psychosocial intervention in adolescents (13 to 18 years).

**Data collection and analysis:** 
We used standard methodological procedures recommended by The Cochrane Collaboration.

**Main results:**
Two trials involving 190 participants were included. One trial compared buprenorphine with clonidine for detoxification. No difference was found for drop out: risk ratio (RR) 0.45 (95% confidence interval (CI): 0.20 to 1.04) and acceptability of treatment: withdrawal score mean difference (MD): 3.97 (95% CI -1.38 to 9.32). More participants in the buprenorphine group initiated naltrexone treatment: RR 11.00 (95% CI 1.58 to 76.55), quality of evidence moderate.The other trial compared maintenance treatment versus detoxification treatment: buprenorphine-naloxone maintenance versus buprenorphine detoxification. For drop out the results were in favour of maintenance treatment: RR 2.67 (95% CI 1.85, 3.86), as well as for results at follow-up RR 1.36 [95% CI 1.05to 1.76); no differences for use of opiate, quality of evidence low.

**Authors&#039; conclusions:** 
It is difficult to draw conclusions on the basis of two trials with few participants. Furthermore, the two studies included did not consider the efficacy of methadone that is still the most frequent drug utilised for the treatment of opioid withdrawal. One possible reason for the lack of evidence could be the difficulty in conducting trials with young people due to practical and ethical reasons.
AN  - CD006749
AU  - Minozzi,
AU  - S.
AU  - Amato,
AU  - L.
AU  - Bellisario,
AU  - C.
AU  - Davoli,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd006749
KW  - Buprenorphine [therapeutic use]
KW  - Clonidine [therapeutic use]
KW  - Maintenance Chemotherapy [methods]
KW  - Naloxone [therapeutic use]
KW  - Naltrexone [therapeutic use]
KW  - Narcotic Antagonists [therapeutic use]
KW  - Opiate Substitution Treatment [methods]
KW  - Opioid-Related Disorders [rehabilitation]
KW  - Patient Dropouts [statistics &amp; numerical data]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Humans[checkword]
KW  - Addictn
PY  - 2014
T2  - Cochrane Database of Systematic Reviews
TI  - Detoxification treatments for opiate dependent adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006749.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006749.pub3/asset/CD006749.pdf?v=1&amp;t=iw7j95fb&amp;s=ae1915cbd2093ff82529ea42d54a586b3dea2de3
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Current guidelines for treatment-resistant depression in adolescents remain inadequate. This study aimed to systematically review the management of treatment-resistant depression in adolescent patients. 

**METHODS: **
We conducted an electronic database search of PUBMED, EMBASE, Cochrane, Web of Science and PsycINFO for studies with adolescent treatment-resistant depression published up to January 2014. Treatment-resistant depression was defined as failure to respond to at least one course of psychological or pharmacological treatment for depression with an adequate dosage, duration, and appropriate compliance during the current illness episode. The Cochrane risk-of-bias method was used to assess the quality of randomized controlled trials. A meta-analysis of all active treatments was conducted. 

**RESULTS: **
Eight studies with 411 depressed adolescents that fit predetermined criteria investigated pharmacological treatments and psychotherapies. Six were open-label studies, and two were randomized controlled trials. The overall response rate for all active treatments investigated was 46% (95% CI 33 to 59; N=411) with a moderately high degree of heterogeneity (I2=76.1%, 95% CI=47%-86%). When only the two randomized trials were included, the overall response rate of active treatment was 53% (95% CI=38-67; N=347). In these randomized trials, SSRI therapy plus CBT was significantly more effective than SSRI therapy alone, while amitriptyline was not more effective than placebo. 

**CONCLUSIONS:**
Approximately half of the adolescents who presented with treatment-refractory depression responded to active treatment, which suggests that practitioners should remain persistent in managing these challenging cases. The combination of antidepressant medication and psychotherapy should be recommended for adolescents who present with treatment-resistant depression.
AN  - 25433401
AU  - Zhou,
AU  - X.
AU  - Michael,
AU  - K.
AU  - D.
AU  - Liu,
AU  - Y.
AU  - Del
AU  - Giovane,
AU  - C.
AU  - Qin,
AU  - B.
AU  - Cohen,
AU  - D.
AU  - Gentile,
AU  - S.
AU  - Xie,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/s12888-014-0340-6
DP  - Ovid Technologies
J2  - BMC Psychiatry
L1  - internal-pdf://0861838045/Zhou-2014-Systematic review of management for.pdf
LA  - English
N1  - Zhou, Xinyu Michael, Kurt D Liu, Yiyun Del Giovane, Cinzia Qin, Bin Cohen, David Gentile, Salvatore Xie, Peng
PY  - 2014
SP  - 340
T2  - BMC Psychiatry
TI  - Systematic review of management for treatment-resistant depression in adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25433401 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25433401&amp;id=doi:10.1186%2Fs12888-014-0340-6&amp;issn=1471-244X&amp;isbn=&amp;volume=14&amp;issue=1&amp;spage=340&amp;pages=340&amp;date=2014&amp;title=BMC+Psychiatry&amp;atitle=Systematic+review+of+management+for+treatment-resistant+depression+in+adolescents.&amp;aulast=Zhou&amp;pid=%3Cauthor%3EZhou+X%3C%2Fauthor%3E%3CAN%3E25433401%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254264/pdf/12888_2014_Article_340.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254264/pdf/12888_2014_Article_340.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobehavioral disorder characterized by over activity and impulsiveness beyond what is considered typical development. 

Studies have been conducted on the effects of external stimulation, in terms of music, and its impact on task performance for children and adolescents with ADHD. The present meta-analysis (n = 5) sought to examine those effects through an effect size analysis. 

The meta-analysis reveals that the music interventions have been minimally effective as an intervention to increase task performance for children and adolescents with ADHD. A critique of the past studies is provided and the need for new improved research on music interventions for ADHD is emphasized. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Maloy, Megan: mmaloy@umail.iu.edu Maloy, Megan, 1625 South Wilcox Street, Apartment 9, Bloomington, IN, US, 47401, mmaloy@umail.iu.edu Maloy, Megan: Indiana University, Bloomington, IN, US Peterson, Rachel: Indiana University, Bloomington, IN, US
AN  - 2015-21453-004
AU  - Maloy,
AU  - M.
AU  - Peterson,
AU  - R.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/pmu0000083
DP  - Ovid Technologies
KW  - attention-deficit/hyperactivity disorder, music intervention, task performance
KW  - *Attention Deficit Disorder with Hyperactivity
KW  - *Intervention
KW  - *Music
KW  - *Performance
KW  - Mathematics
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
KW  - Human Male Female
L1  - internal-pdf://1111647843/328.pdf
LA  - English
M3  - Meta Analysis
PY  - 2014
SP  - 328-339
T2  - Psychomusicology
TI  - A meta-analysis of the effectiveness of music interventions for children and adolescents with attention-deficit/hyperactivity disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2015-21453-004http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2Fpmu0000083&amp;issn=0275-3987&amp;isbn=&amp;volume=24&amp;issue=4&amp;spage=328&amp;pages=328-339&amp;date=2014&amp;title=Psychomusicology%3A+Music%2C+Mind%2C+and+Brain&amp;atitle=A+meta-analysis+of+the+effectiveness+of+music+interventions+for+children+and+adolescents+with+attention-deficit%2Fhyperactivity+disorder.&amp;aulast=Maloy&amp;pid=%3Cauthor%3EMaloy%2C+Megan%3C%2Fauthor%3E%3CAN%3E2015-21453-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 24
ER  -
TY  - JOUR
AB  - **Objective **
To evaluate and quantify the evidence for behavioral interventions for pediatric insomnia. 

**Methods **
Meta-analysis of 16 controlled trials and qualitative analysis of 12 within-subject studies were conducted (total n = 2,560). 

**Results **
Meta-analysis found significant effects for four specified sleep outcomes: sleep-onset latency, number of night wakings, and duration of night wakings, and sleep efficiency, with small to large effect sizes across the controlled clinical trials involving typical children. No significant effects were found for the two studies conducted with special needs populations. Finally, within-subjects studies demonstrated significant effects for all sleep outcomes with large effect sizes. Risk of bias assessment and GRADE ratings of the quality of the evidence are described. 

**Conclusion **
Moderate-level evidence supports behavioral interventions for pediatric insomnia in young children. However, low evidence for children, adolescents, and those with special needs (due to a lack of studies that met inclusion criteria) highlights the need for future research.
AD  - [Meltzer, Lisa J.] Natl Jewish Hlth, Dept Pediat, Denver, CO 80206 USA. [Mindell, Jodi A.] St Josephs Hosp, Dept Psychol, Nashua, NH USA. [Mindell, Jodi A.] Childrens Hosp Philadelphia, Sleep Ctr, Philadelphia, PA USA. Meltzer, LJ (reprint author), Natl Jewish Hlth, Dept Pediat, 1400 Jackson St,G311, Denver, CO 80206 USA. meltzerL@njhealth.org
AN  - WOS:000343398100011
AU  - Meltzer,
AU  - L.
AU  - J.
AU  - Mindell,
AU  - J.
AU  - A.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1093/jpepsy/jsu041
J2  - J. Pediatr. Psychol.
KW  - bedtime problems behavioral insomnia of childhood behavioral treatment insomnia night wakings pediatric insomnia treatment RANDOMIZED CONTROLLED-TRIAL SCHOOL-AGED CHILDREN INFANT SLEEP PROBLEMS AUTISM SPECTRUM DISORDERS ATTENTION-DEFICIT/HYPERACTIVITY D
L1  - internal-pdf://2937348705/Meltzer-2014-Systematic Review and Meta-Analys.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AR2FD Times Cited: 1 Cited Reference Count: 87 Meltzer, Lisa J. Mindell, Jodi A. 1 OXFORD UNIV PRESS INC CARY J PEDIATR PSYCHOL SI
PY  - 2014
SP  - 932-948
T2  - Journal of Pediatric Psychology
TI  - Systematic Review and Meta-Analysis of Behavioral Interventions for Pediatric Insomnia
UR  - &lt;Go to ISI&gt;://WOS:000343398100011http://jpepsy.oxfordjournals.org/content/39/8/932.longhttp://jpepsy.oxfordjournals.org/content/39/8/932.full.pdf
UR  - https://watermark.silverchair.com/jsu041.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAdswggHXBgkqhkiG9w0BBwagggHIMIIBxAIBADCCAb0GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMQfPZHAzupSvFCOCPAgEQgIIBjm1naKqYrFAzYXEr58mndsXKm5_Hm7PfXYf4Gk2GLoCeI2QcEZvcm4GmAjOfVNLxuh5z6s6q80s5hG30Q0rz5IcvnhO7vGnNXw_Qu0cMGBmJXjDiJLUY7hwgU_LT_TliCpis7BccH4DLylOxy2IR0Zi_WQ0LSaky093fu6cGUGj6lzlww7J11BuE9VxWAFSROa4_NCU2KSoVPE5wBnPo2cNElnUuep8Q7ung3tRwWZFhG3Az2a1sACpPqcMM3HQvUe0s7Vvk-q_Dv_1lui5R9A3XoPAPWA7hNtvHGQd_QrKLCBFJv32hGnO4Hz57AKPj8cZtc5sgkXWs9fvJHtlRrFcz2Xek5L4icNdmq6Nb1fJmrYliZvLS8DD4lgkaRmTNa1oFpZ7vIyI-mjm55SVNeNvRrgXsG1r5qSo1ClZ78JUF_O9EfhkoTH2Krd4UlCPeG41BNdws-QL578rRpVB3VyHfNFAs1ZQh5NDC8eiXRXHfIuVnZZWXVt2FDRUerGrxvFuuPthHOQk14jwgt4nH
VL  - 39
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To meta-analyze the efficacy and safety of alpha-2 agonists in pediatric attention-deficit/hyperactivity disorder (ADHD). 

**METHOD: **
We searched MEDLINE, EMBASE, Cochrane Library, CINAHL, and PsycINFO until May 2013 for randomized trials comparing alpha-2 agonists with placebo in ADHD youth. Primary outcome was reduction in overall ADHD symptoms. Secondary outcomes included hyperactivity/impulsivity, inattentiveness, oppositional defiant disorder symptoms (ODD symptoms), all-cause discontinuation, specific-cause discontinuation, and adverse effects. Standardized mean differences (SMD), relative risk (RR), and number-needed-to-treat/number-needed-to-harm (NNT/NNH) were calculated. Data were analyzed separately in monotherapy and as add-on to psychostimulants. 

**RESULTS:** 
Altogether, 12 studies (N = 2,276) were included. Across 9 studies (n = 1,550), alpha-2 agonist monotherapy significantly reduced overall ADHD symptoms (SMD = -0.59, p &lt; .00001), hyperactivity/impulsivity (SMD = -0.56, p &lt; .00001), inattention (SMD = -0.57, p &lt; .00001), and ODD symptoms (SMD = -0.44, p = .0004). Similarly, alpha-2 agonist add-on treatment (3 studies, n = 726) significantly reduced overall ADHD symptoms (SMD = -0.36, p &lt; .0001), hyperactivity/impulsivity (SMD = -0.33, p &lt; .0001), and inattention (SMD = -0.34, p &lt; .0001), but effect sizes were lower than in monotherapy trials (p = .03-0.04). As monotherapy, alpha-2 agonists had lower all-cause (RR = 0.70, p = .01, NNT = 10) and inefficacy-related (RR = 0.39, p &lt; .0001) discontinuations than did placebo; however, intolerability-related discontinuation was similar, despite significantly more common fatigue (NNH = 10), sedation (NNH = 17), and somnolence (NNH = 4) and significantly greater hypotensive (clonidine-IR), bradycardic (clonidine-IR), and QTc prolonging (guanfacine-XR) effects. Added to stimulants, alpha-2 agonists had all-cause and specific-cause discontinuations that were comparable to those of placebo, but somnolence (NNH = 10) was more common, and hypotensive and bradycardic effects (clonidine-XR and guanfacine-XR) were greater than with placebo. 

**CONCLUSIONS: **
alpha-2 Agonist monotherapy and, possibly to a lesser extent, co-treatment, are significantly superior to placebo for overall, hyperactivity, and inattentive ADHD symptoms. Efficacy advantages need to be balanced against fatigue, somnolence/sedation, hypotension, bradycardia, and possibly QTc prolongation.

Copyright &copy; 2014 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
AD  - Hirota,Tomoya. Vanderbilt University Medical Center. Schwartz,Shimon. Zucker Hillside Hospital, Psychiatry Research, North Shore-Long Island Jewish (LIJ) Health System, and Montefiore Medical Center. Correll,Christoph U. Zucker Hillside Hospital, Psychiatry Research, North Shore-Long Island Jewish Health System, Hofstra North Shore LIJ School of Medicine, Albert Einstein College of Medicine, and the Feinstein Institute for Medical Research. Electronic address: ccorrell@lij.edu.
AN  - 24472251
AU  - Hirota,
AU  - T.
AU  - Schwartz,
AU  - S.
AU  - Correll,
AU  - C.
AU  - U.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2013.11.009
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
LA  - English
N1  - Hirota, Tomoya Schwartz, Shimon Correll, Christoph U Comment in: J Am Acad Child Adolesc Psychiatry. 2014 Feb;53(2):135-7; PMID: 24472248 S0890-8567(13)00818-6
PY  - 2014
SP  - 153-73
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Alpha-2 agonists for attention-deficit/hyperactivity disorder in youth: a systematic review and meta-analysis of monotherapy and add-on trials to stimulant therapy
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24472251
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24472251&amp;id=doi:10.1016%2Fj.jaac.2013.11.009&amp;issn=0890-8567&amp;isbn=&amp;volume=53&amp;issue=2&amp;spage=153&amp;pages=153-73&amp;date=2014&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Alpha-2+agonists+for+attention-deficit%2Fhyperactivity+disorder+in+youth%3A+a+systematic+review+and+meta-analysis+of+monotherapy+and+add-on+trials+to+stimulant+therapy.&amp;aulast=Hirota&amp;pid=%3Cauthor%3EHirota+T%3C%2Fauthor%3E%3CAN%3E24472251%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0890856713008186/1-s2.0-S0890856713008186-main.pdf?_tid=023032d4-1674-11e5-8949-00000aab0f6c&amp;acdnat=1434712501_dc4ddd6c1582aeba0459ff5ab0460ff8
VL  - 53
ER  -
TY  - JOUR
AB  - Externalising behaviour in childhood is a prevalent problem in the field of child and adolescent mental health. 

Parenting interventions are widely accepted as efficacious treatment options for reducing externalising behaviour, yet practical and psychological barriers limit their accessibility. 

This review aims to establish the evidence base of self-directed (SD) parenting interventions for externalising behaviour problems. 

Electronic searches of PubMed, Web of Knowledge, Psychinfo, Embase and CENTRAL databases and manual searches of reference lists of relevant reviews identified randomised controlled trials and cluster randomised controlled trials examining the efficacy of SD interventions compared to no-treatment or active control groups. 

A random-effect meta-analysis estimated pooled standard mean difference (SMD) for SD interventions on measures of externalising child behaviour. 

Secondary analyses examined their effect on measures of parenting behaviour, parental stress and mood and parenting efficacy. Eleven eligible trials were included in the analyses. SD interventions had a large effect on parent report of externalising child behaviour (SMD = 1.01, 95 % CI: 0.77-1.24); although this effect was not upheld by analyses of observed child behaviour. 

Secondary analyses revealed effects of small to moderate magnitude on measures of parenting behaviour, parental mood and stress and parenting efficacy. 

An analysis comparing SD interventions with therapist-led parenting interventions revealed no significant difference on parent-reported measures of externalising child behaviour. SD interventions are associated with improvements in parental perception of externalising child behaviour and parental behaviour and well-being. 

Future research should further investigate the relative efficacy and cost-effectiveness of SD interventions compared to therapist-led interventions.
AD  - [Tarver, Joanne; Daley, David; Lockwood, Joanna; Sayal, Kapil] Univ Nottingham, Inst Mental Hlth, Div Psychiat &amp; Appl Psychol, Nottingham NG7 2TU, England. [Tarver, Joanne; Daley, David; Sayal, Kapil] Univ Nottingham, Ctr ADHD &amp; Neurodev Disorders Lifespan CANDAL, Nottingham NG7 2TU, England. Daley, D (reprint author), Univ Nottingham, Inst Mental Hlth, Div Psychiat &amp; Appl Psychol, Innovat Pk,Triumph Rd, Nottingham NG7 2TU, England. mcxjht@nottingham.ac.uk; david.daley@nottingham.ac.uk
AN  - WOS:000345639200002
AU  - Tarver,
AU  - J.
AU  - Daley,
AU  - D.
AU  - Lockwood,
AU  - J.
AU  - Sayal,
AU  - K.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-014-0556-5
J2  - Eur. Child Adolesc. Psych.
KW  - Disruptive behaviour ADHD Self-help Self-administered Parent training ATTENTION-DEFICIT/HYPERACTIVITY DISORDER RANDOMIZED CONTROLLED-TRIALS CONDUCT-PROBLEM CHILDREN FAMILY INTERVENTION TREATMENT RESPONSE REMOTE AREAS PROGRAM RISK ADHD PSYCHOPATHOLOGY Ps
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AU5IC Times Cited: 2 Cited Reference Count: 55 Tarver, Joanne Daley, David Lockwood, Joanna Sayal, Kapil NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC); Institute of Mental Health at the University of Nottingham JT and KS are partially funded by the NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC) for Nottinghamshire, Derbyshire, Lincolnshire and JT is partly funded by the Institute of Mental Health at the University of Nottingham. 2 SPRINGER NEW YORK EUR CHILD ADOLES PSY
PY  - 2014
SP  - 1123-1137
T2  - European Child &amp; Adolescent Psychiatry
TI  - Are self-directed parenting interventions sufficient for externalising behaviour problems in childhood? A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000345639200002http://download.springer.com/static/pdf/356/art%253A10.1007%252Fs00787-014-0556-5.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-014-0556-5&amp;token2=exp=1434977931~acl=%2Fstatic%2Fpdf%2F356%2Fart%25253A10.1007%25252Fs00787-014-0556-5.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-014-0556-5*~hmac=22d56eef9e227e5252315c0ea01f4f6266eef308ac1dde3b897cfe1be217f794
VL  - 23
ER  -
TY  - JOUR
AB  - The purpose of this review was to evaluate the methodological strength and overall effectiveness of the research underlying the FRIENDS program for preventing anxiety in students at low and elevated risk for developing anxiety disorders. 

Meta-analytic findings provided mixed results, with low-risk students exposed to the program having demonstrated small improvements over comparisons for immediate posttest measures of anxiety. 

Findings drawn from follow-up data collection periods indicated that low-risk students sustained initial gains on anxiety over 12 months but not beyond. 

In addition, no immediate posttest difference was found between students at elevated risk on measures of anxiety. 

These findings are discussed in terms of practical and methodological limitations of the body of research.
AD  - [Maggin, Daniel M.] Univ Illinois, Chicago, IL 60607 USA. [Johnson, Austin H.] Univ Connecticut, Storrs, CT USA. Maggin, DM (reprint author), Univ Illinois, Dept Special Educ, 1040 West Harrison St,M-C 147, Chicago, IL 60607 USA. dmaggin@uic.edu
AN  - WOS:000341747700005
AU  - Maggin,
AU  - D.
AU  - M.
AU  - Johnson,
AU  - A.
AU  - H.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1353/etc.2014.0018
J2  - Educ. Treat. Child.
KW  - Anxiety FRIENDS Meta-analysis Program Evaluation PRIMARY-SCHOOL CHILDREN MENTAL-HEALTH PROBLEMS EARLY IDENTIFICATION SYSTEMATIC REVIEWS CLINICAL-TRIALS DISORDERS ADOLESCENTS SYMPTOMS ISSUES INTERVENTIONS Education, Special Rehabilitation
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AP0JN Times Cited: 0 Cited Reference Count: 66 Maggin, Daniel M. Johnson, Austin H. WEST VIRGINIA UNIV PRESS MORGANTOWN EDUC TREAT CHILD
PY  - 2014
SP  - 277-306
T2  - Education and Treatment of Children
TI  - A Meta-Analytic Evaluation of the FRIENDS Program for Preventing Anxiety in Student Populations
UR  - &lt;Go to ISI&gt;://WOS:000341747700005
VL  - 37
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
The incidence of psychological, physical, and sexual violence in intimate dating relationships has a significant impact on young people. These issues are of great concern to researchers, educators, and administrators who strive to help youth be happy and healthy. This review focused on prevention and intervention efforts implemented in schools that sought to reduce or prevent incidents of dating violence. 

**OBJECTIVES** 
The main objective of this review was to evaluate and synthesize the efficacy of school-based interventions that sought to reduce or prevent teen dating violence or sexual violence in intimate relationships. Specifically this review evaluated the impact of dating violence prevention programs implemented in middle and high schools on changing attitudes or beliefs supportive of teen dating violence, reducing incidents of dating violence perpetration, or reducing incidents of dating violence victimization. Additionally, this review examined potential substantive or methodological variables (e.g., program characteristics, age, gender, location) that moderated the effect sizes. 

**SEARCH STRATEGY** 
An extensive search strategy was used to identify qualifying studies. Various electronic bibliographic databases were searched in July 2013, along with government databases, grey literature databases, and citations in other reviews. In addition, we searched the reference lists of primary studies, hand searched relevant journals, and searched the Internet using Google and Google Scholar. We also contacted researchers who have published extensively in the area of teen dating violence and researchers who have received grants to implement teen dating violence prevention programs to identify studies in press or in preparation. Neither language nor date restrictions were applied to the searches. 

**SELECTION CRITERIA** 
Studies were required to meet several criteria to be eligible for inclusion. Studies must: &bull; have a well-defined control group. &bull; include a school-based intervention, implemented with students between 4th and 12th grade. &bull; have a primary goal of reducing or preventing teen dating violence or sexual violence in intimate relationships. &bull; measure the impact of the program on either attitude change, frequency of intimate partner violence perpetration or victimization, teen dating violence knowledge, or on the ability to recognize both safe and unhealthy behaviors in intimate partner disputes. Studies were excluded if they measured the above outcomes as secondary outcomes. Studies that utilized community centers or other locations outside the brick-and-mortar schools were also excluded. 

**DATA COLLECTION AND ANALYSIS
The literature search yielded a total of 1,608 references, of which 90 were deemed potentially relevant and retrieved for additional screening. Of these 90 studies, 23 were included in the study after a full review. Meta-analysis was used to examine the effects of school-based programs versus a control group on increasing knowledge of teen dating violence, changing attitudes or beliefs supportive of teen dating violence, reducing incidents of dating violence perpetration, and reducing incidents of dating violence victimization. A three-level meta-analytic model was utilized to synthesize the effect sizes. RESULTS This systematic review found that prevention programs do have an impact on teen dating violence knowledge and attitudes. At post-test, students in the intervention conditions increased their knowledge and endorsed attitudes that were less accepting of violence in relationships. In addition, at post-test, prevention students were less accepting of rape myths and reported an increased awareness of appropriate approaches to conflict resolution. The positive results for teen dating violence knowledge and attitudes were supported at follow-up. However the results for dating violence perpetration and victimization were less encouraging. Although only a limited number of studies focused on these outcomes, the results indicated that prevention programs are not impacting these b haviors to great extent. Moderation analysis did not find any significant variables that impacted the effect sizes. 

**AUTHORS&rsquo; CONCLUSIONS
The results of this review are tentatively encouraging, but also highlight the need for modifications to programs in order to support schools using time and resources to implement teen dating violence prevention programs. Specifically, programs will need to be refined so that they support behavior change, with future research focusing on program development that explicitly seeks to incorporate skill-building components in an effort to impart behavior change. Additionally, future research should explore the role of bystanders more explicitly, examining how prevention programs may shift the peer culture to be less tolerant of dating violence.
AU  - De
AU  - La,
AU  - Rue,
AU  - L.
AU  - Polanin,
AU  - J.
AU  - Espelage,
AU  - D.
AU  - Pigott,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2014.7
PY  - 2014
T2  - Campbell Systematic Reviews
TI  - School-Based Interventions to Reduce Dating and Sexual Violence: A Systematic Review
ER  -
TY  - JOUR
AB  - Serious games (computerised interventions which utilise gaming for serious purposes) have been shown to support improved outcomes in several health conditions. 

We aimed to review evidence regarding serious games for depression. We undertook electronic searches of PsycInfo, EMBASE and Medline, using terms relevant to computer games and depression. 

We included fulltext articles published in English in peer-reviewed literature since 2000, where the intervention was designed to treat or prevent depression and which included pre-and post-intervention measurement of depression. Nine studies relating to a total of six interventions met inclusion criteria. 

Most studies were small and were carried out by the developers of the programs. All were tested with young people (ages between 9 and 25 years). Most reported promising results with some positive impact on depression although one universal program had mixed results. Serious gaming interventions show promise for depression, however evidence is currently very limited. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Fleming, Theresa M.: t.fleming@auckland.ac.nz Fleming, Theresa M.: Department of Psychological Medicine, University of Auckland, Private Bag 92019, Auckland, New Zealand, t.fleming@auckland.ac.nz Fleming, Theresa M.: Department of Psychological Medicine, University of Auckland, Auckland, New Zealand Cheek, Colleen: University of Tasmania, Rural Clinical School, Burnie, TAS, Australia Merry, Sally N.: Department of Psychological Medicine, University of Auckland, Auckland, New Zealand Thabrew, Hiran: Department of Psychological Medicine, University of Auckland, Auckland, New Zealand Bridgman, Heather: University of Tasmania, Centre for Rural Health, Launceston, TAS, Australia Stasiak, Karolina: Department of Psychological Medicine, University of Auckland, Auckland, New Zealand Shepherd, Matthew: School of Counselling, Human Services and Social Work, Faculty of Education, University of Auckland, Auckland, New Zealand Perry, Yael: Black Dog Institute, University of New South Wales, Randwick, NSW, Australia Hetrick, Sarah: Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Parkville, VIC, Australia
AN  - 2015-10551-008
AU  - Fleming,
AU  - T.
AU  - M.
AU  - Cheek,
AU  - C.
AU  - Merry,
AU  - S.
AU  - N.
AU  - Thabrew,
AU  - H.
AU  - Bridgman,
AU  - H.
AU  - Stasiak,
AU  - K.
AU  - Shepherd,
AU  - M.
AU  - Perry,
AU  - Y.
AU  - Hetrick,
AU  - S.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.5944/rppc.vol.19.num.3.2014.13904
DP  - Ovid Technologies
KW  - Depression, adolescents, computerised CBT, serious gaming, e-therapy
KW  - *Computer Games
KW  - *Major Depression
KW  - *Online Therapy
KW  - *Prevention
KW  - Treatment Effectiveness Evaluation
KW  - Treatment Outcomes
KW  - Specialized Interventions [3350]
KW  - Human Childhood (birth-12 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older) Young Adulthood (18-29 yrs)
L1  - internal-pdf://0574547042/08_2014_n3_varios.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2014
SP  - 227-242
T2  - Revista de Psicopatologia y Psicologia Clinica
TI  - Serious games for the treatment or prevention of depression: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2015-10551-008http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=1136-5420&amp;isbn=&amp;volume=19&amp;issue=3&amp;spage=227&amp;pages=227-242&amp;date=2014&amp;title=Revista+de+Psicopatologia+y+Psicologia+Clinica&amp;atitle=Serious+games+for+the+treatment+or+prevention+of+depression%3A+A+systematic+review.&amp;aulast=Fleming&amp;pid=%3Cauthor%3EFleming%2C+Theresa+M%3C%2Fauthor%3E%3CAN%3E2015-10551-008%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 19
ER  -
TY  - JOUR
AB  - **Purpose: **
Intimate partner violence (IPV) is a pervasive global health issue affecting adolescents. We reviewed randomized controlled trials of interventions to reduce physical, sexual, and psychological violence perpetration and victimization among adolescents. 

**Methods: **
PUBMED, CINAHL, Science Direct, EMbase, PsychLIT, ISI Web of Science, Scopus, and the Cochrane database were searched for English language papers published up to the end of February 2013. 

**Results: **
Eight articles reporting on six randomized controlled trials were retrieved. Four interventions contained both school and community components. We found positive intervention effects on IPV perpetration (three studies) and IPV victimization (one study). Compared with the studies with no effects on IPV, the effective interventions were of longer duration, and were implemented in more than one setting. There were quality issues in all six trials. 

**Conclusion:**
Interventions targeting perpetration and victimization of IPV among adolescents can be effective. Those interventions are more likely to be based in multiple settings, and focus on key people in the adolescents&#039; environment. Future trials should assess perpetration and victimization of IPV among male and female adolescents with and without prior experiences with IPV, taking gender differences into account. 

(C) 2014 Society for Adolescent Health and Medicine. All rights reserved.
AD  - [De Koker, Petra; Mathews, Catherine; Zuch, Melanie; Mason-Jones, Amanda J.] Univ Cape Town, Adolescent Hlth Res Unit, ZA-7700 Cape Town, South Africa. [De Koker, Petra] Univ Ghent, Int Ctr Reprod Hlth, B-9000 Ghent, Belgium. [Mathews, Catherine; Mason-Jones, Amanda J.] MRC, Hlth Syst Res Unit, Cape Town, South Africa. [Zuch, Melanie] Brown Univ, Providence, RI 02912 USA. [Bastien, Sheri] Univ Oslo, Inst Basic Med Sci, Fac Med, Oslo, Norway. [Mason-Jones, Amanda J.] Univ York, Dept Hlth Sci, York YO10 5DD, N Yorkshire, England. De Koker, P (reprint author), Univ Cape Town, ZA-7700 Cape Town, South Africa. petra.dekoker@gmail.com; amanda.mason-jones@york.ac.uk
AN  - WOS:000329062400002
AU  - De
AU  - Koker,
AU  - P.
AU  - Mathews,
AU  - C.
AU  - Zuch,
AU  - M.
AU  - Bastien,
AU  - S.
AU  - Mason-Jones,
AU  - A.
AU  - J.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jadohealth.2013.08.008
J2  - J. Adolesc. Health
KW  - RANDOMIZED-CONTROLLED-TRIAL GENDER-BASED VIOLENCE SAFE DATES PROGRAM YOUNG-ADULT MEN DATING VIOLENCE SOUTH-AFRICA DOMESTIC VIOLENCE SEXUAL RISK WOMENS HEALTH HIV RISK Psychology, Developmental Public, Environmental &amp; Occupational Health Pediatrics
L1  - internal-pdf://3795702840/De Koker.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 280WV Times Cited: 3 Cited Reference Count: 51 De Koker, Petra Mathews, Catherine Zuch, Melanie Bastien, Sheri Mason-Jones, Amanda J. EC [241945] The full title of the project is: &quot;Promoting sexual and reproductive health among adolescents in southern and eastern Africae- mobilizing schools, parents and communities&quot;. Acronym: PREPARE. The PREPARE study is funded by the EC Health research program (under the 7th Framework Program). Grant Agreement number: 241945. The partners and principal investigators include: University of Cape Town (Cathy Mathews), Muhimbili University College of Health Sciences (Sylvia Kaaya), University of Limpopo (Hans Onya), Makerere University (Anne Katahoire), Maastricht University (Hein de Vries), University of Exeter (Charles Abraham), University of Oslo (Knut-Inge Klepp), University of Bergen (Leif Edvard Aaro, coordinator). See also the project homepage http://prepare.b.uib.no/. 3 ELSEVIER SCIENCE INC NEW YORK J ADOLESCENT HEALTH
PY  - 2014
SP  - 3-13
T2  - Journal of Adolescent Health
TI  - A Systematic Review of Interventions for Preventing Adolescent Intimate Partner Violence
UR  - &lt;Go to ISI&gt;://WOS:000329062400002http://ac.els-cdn.com/S1054139X13004606/1-s2.0-S1054139X13004606-main.pdf?_tid=822a1b9a-165a-11e5-ae4c-00000aacb35f&amp;acdnat=1434701549_bffdcad8e487d3bfe148066c6b8ad457
VL  - 54
ER  -
TY  - JOUR
AB  - **Context **
Medical practitioners are now seeing more children younger than 15 y who are developing childhood anorexia. Hua Tuo chiropractic treatments are an ancient and practical massage therapy and are a type of Tui Na therapy, which has been used for curing childhood anorexia for thousands of years in China. Research literature suggests that chiropractic care produces outcomes at least comparable with alternative treatments. 

**Objective **
The research team intended to perform a systematic review to identify and synthesize evidence on the efficacy of Tui Na for treatment of childhood anorexia. 

**Design **
Systematic searches were conducted for studies evaluating Tui Na therapy in electronic databases MEDLINE, EMBASE, PsychINFO, the Cochrane Library, the Cumulative Index to Nursing and Allied Health Literature, the Midwives Information and Resource Service, the Health Management Information Consortium, the Health Management and Information Service, PubMed, the Chinese National Knowledge Infrastructure (CNKI), the Chinese Biomedical Literature Database (CBM), the Chinese Scientific Journal Database VIP, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), and the Chinese Clinical Trial Register-from inception to November 2011. The research team hand-searched reference lists and journals, extracted data from the papers, and assessed the quality of the research. 

**Participants **
Participants of the reviewed studies were infants and children younger than 15 y. 

**Results **
Of the 109 papers identified, 3 papers reported on randomized, controlled trials (RCTs) involving 332 patients; 45 covered cohort or quasi-experimental studies; and 61 discussed nonintervention studies. Meta-analysis results from the 3 RCTs showed that Tui Na can improve the curative effect compared with oral medicine that is used for infants and young children with anorexia and can also increase a child&#039;s weight. 

**Conclusions **
The level of evidence reported was mixed, but given the available evidence, the research team concluded that Tui Na therapy was a viable intervention that could benefit infants and young children with anorexia. No serious adverse events were reported. Larger randomized, controlled trials are required to explore the effects of Tui Na therapy for treatment of childhood anorexia further.
AD  - [Qiao Cuixia; Zhang Xinfeng] Inst Tradit Chinese Med, Dept Oncol, Zhengzhou, Henan Province, Peoples R China. [Zhang Xinfeng] Integrated Tradit Chinese Med, Zhengzhou, Peoples R China. [Cai Xiaoping] Zhengzhou Univ, Tumor Hosp, Henan Canc Hosp, Western Med Dept, Zhengzhou 450052, Peoples R China. Qiao, CX (reprint author), Inst Tradit Chinese Med, Dept Oncol, Zhengzhou, Henan Province, Peoples R China. qiaocuixia@126.com
AN  - WOS:000348094600008
AU  - Xia,
AU  - Q.
AU  - C.
AU  - Feng,
AU  - Z.
AU  - X.
AU  - Ping,
AU  - C.
AU  - X.
DA  - Sep-Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /CRDWeb/ShowRecord.asp
J2  - Altern. Ther. Health Med.
KW  - CHINESE MEDICINE CARE Integrative &amp; Complementary Medicine
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AZ2YG Times Cited: 0 Cited Reference Count: 19 Qiao Cuixia Zhang Xinfeng Cai Xiaoping Key Clinical Construction Program of the National Project [132102310221] This study was supported by grants from the Key Clinical Construction Program of the National Project (Project No. 132102310221). INNOVISION COMMUNICATIONS ALISO VIEJO ALTERN THER HEALTH M
PY  - 2014
SP  - 45-52
T2  - Alternative Therapies in Health and Medicine
TI  - Evaluating the Efficacy of Tui Na in Treatment of Childhood Anorexia: A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000348094600008
VL  - 20
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Although long-term treatment is a core aspect of the management of children and adolescents with bipolar disorder (BD), most clinical recommendations are based on results from short-term studies or adult data. In order to guide clinical practice, we review the efficacy and safety profile of mood stabilizers, antipsychotics, and other pharmacological strategies for the long-term treatment of BD in pediatric patients. 

**METHODS: **
A MEDLINE, EMBASE, Cochrane and PsycInfo search (inception through November 2013) was performed to identify prospective studies longer than 12 weeks assessing the use of pharmacological strategies for the long-term treatment of BD in pediatric patients (0-18 years of age). 

**RESULTS: **
Four randomized controlled trials (RCT) [three placebo-controlled (assessing aripiprazole (2) and flax oil), and one head-to-head comparison of lithium vs. divalproex], and thirteen noncontrolled studies (six open-label studies assessing lithium or anticonvulsants, five assessing second-generation antipsychotics (SGAs) and four assessing combination strategies) were included in the review. Aripiprazole has shown efficacy for relapse prevention in children with pediatric bipolar disorder (PBD) 4-9 years of age in one placebo-controlled RCT. Positive results have been reported in noncontrolled studies with quetiapine and lithium for relapse prevention, as well as with lithium, quetiapine, ziprasidone, and the combination of risperidone and divalproex or lithium for long-term symptom reduction in PBD. The most frequently reported adverse events in children and adolescents treated with lithium and anticonvulsants are gastrointestinal and neurological, whereas use of SGAs is mainly related to weight gain and sedation. 

**CONCLUSION: **
According to the limited empirical evidence, aripiprazole can be useful for relapse prevention in children with PBD. Given the lack of consistent efficacy data, clinical decision making should be based on individual clinical aspects and safety concerns.

Copyright 
&copy; 2014 The Authors. Journal of Child Psychology and Psychiatry. 
&copy; 2014 Association for Child and Adolescent Mental Health.
AD  - Diaz-Caneja,Covadonga M. Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Maranon, CIBERSAM, IiSGM, School of Medicine, Universidad Complutense, Madrid, Spain.
AN  - 24905547
AU  - Diaz-Caneja,
AU  - C.
AU  - Moreno,
AU  - C.
AU  - Llorente,
AU  - C.
AU  - Espliego,
AU  - A.
AU  - Arango,
AU  - C.
AU  - Moreno,
AU  - D.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jcpp.12271
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Diaz-Caneja, Covadonga M Moreno, Carmen Llorente, Cloe Espliego, Ana Arango, Celso Moreno, Dolores
PY  - 2014
SP  - 959-80
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Practitioner review: Long-term pharmacological treatment of pediatric bipolar disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24905547
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24905547&amp;id=doi:10.1111%2Fjcpp.12271&amp;issn=0021-9630&amp;isbn=&amp;volume=55&amp;issue=9&amp;spage=959&amp;pages=959-80&amp;date=2014&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Practitioner+review%3A+Long-term+pharmacological+treatment+of+pediatric+bipolar+disorder.&amp;aulast=Diaz-Caneja&amp;pid=%3Cauthor%3EDiaz-Caneja+CM%3C%2Fauthor%3E%3CAN%3E24905547%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/jcpp.12271/asset/jcpp12271.pdf?v=1&amp;t=ib3hh07n&amp;s=9b846e6327e1e88a6263089eb8971d37e8e1d991
VL  - 55
ER  -
TY  - JOUR
AB  - This is a systematic review of the impact of communication interventions on the social communication skills of infants and toddlers with or at-risk for autism spectrum disorder (ASD). 

A priori clinical questions accompanied by specific inclusion and exclusion criteria informed the extensive literature search that was conducted in multiple databases (e.g., PubMed). Twenty-six studies were accepted for this review. 

Outcomes were reported by social communication category (i.e., joint attention, social reciprocity, and language and related cognitive skills) and communication developmental stage (i.e., prelinguistic, emerging language). 

Primarily positive treatment effects were revealed in the majority of outcome categories for which social communication data were available. 

However, the presence of intervention and outcome measure heterogeneity precluded a clear determination of intervention effects. 

Future research should address these issues while also evaluating multiple outcomes and adding a strong family component designed to enhance child active engagement.
AD  - [Morgan, Lindee J.] Florida State Univ, Autism Inst, Tallahassee, FL 32306 USA. [Rubin, Emily] Marcus Autism Ctr, Atlanta, GA USA. [Coleman, Jaumeiko J.; Frymark, Tobi; Wang, Beverly P.] Amer Speech Language Hearing Assoc, Rockville, MD 20850 USA. [Cannon, Laura J.] Univ Maryland, College Pk, MD 20742 USA. Coleman, JJ (reprint author), Amer Speech Language Hearing Assoc, Natl Ctr Evidence Based Practice, 2200 Res Blvd,245, Rockville, MD 20850 USA. jcoleman@asha.org
AN  - WOS:000344609400005
AU  - Morgan,
AU  - L.
AU  - J.
AU  - Rubin,
AU  - E.
AU  - Coleman,
AU  - J.
AU  - J.
AU  - Frymark,
AU  - T.
AU  - Wang,
AU  - B.
AU  - P.
AU  - Cannon,
AU  - L.
AU  - J.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1088357614539835
J2  - Focus Autism Dev. Disabil.
KW  - autism autism spectrum disorder social communication pervasive developmental disorder speech-language pathology intervention RANDOMIZED CONTROLLED-TRIAL SPECTRUM DISORDERS JOINT ATTENTION YOUNG-CHILDREN PARENTS MODEL ENGAGEMENT LANGUAGE THERAPY Educatio
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AT0EG Times Cited: 0 Cited Reference Count: 44 Morgan, Lindee J. Rubin, Emily Coleman, Jaumeiko J. Frymark, Tobi Wang, Beverly P. Cannon, Laura J. SAGE PUBLICATIONS INC THOUSAND OAKS FOCUS AUTISM DEV DIS
PY  - 2014
SP  - 246-256
T2  - Focus on Autism and Other Developmental Disabilities
TI  - Impact of Social Communication Interventions on Infants and Toddlers With or At-Risk for Autism: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000344609400005http://foa.sagepub.com/content/29/4/246http://foa.sagepub.com/content/29/4/246.full.pdf
VL  - 29
ER  -
TY  - JOUR
AB  - **Background: **
Effective treatments for obsessive-compulsive disorder (OCD) include behavioral therapy (exposure and response/ritual prevention and cognitive behavioral therapy) and serotonin-reuptake inhibitors (SRIs); however, the relative efficacy of these treatments is not well established. We sought to review evidence from head-to-head randomized-controlled trials (RCTs) of behavioral therapy and SRIs in the treatment of OCD. 

**Methods: **
A systematic search of multiple databases was conducted from first available date to June 30, 2012, for RCTs in the treatment of OCD among outpatients, comparing behavioral therapy and SRIs, alone or combined. Two independent reviewers evaluated studies for eligibility and risk of bias. The main outcome measure was posttreatment mean Yale-Brown Obsessive-Compulsive Scale (YBOCS) score. 

**Results: **
We identified 2,186 unique articles. Fifteen articles were included, describing 13 RCTs. Pooled standardized mean difference (SMD; 95% confidence intervals) in YBOCS score significantly favored behavioral therapy over SRIs (0.37; 0.10, 0.64; P = .007), but not in a subset of trials that used selective SRIs (0.22; -0.02, 0.47; P = .070). Within individual trials, effect sizes significantly favored the combination of behavioral therapy plus an SRI over an SRI, but not behavioral therapy, alone. 

**Conclusions: **
This review provides evidence that, among outpatients with OCD, behavioral therapy is more effective than SRIs, overall, but not selective SRIs. Furthermore, the combination of behavioral therapy plus an SRI is more effective than an SRI alone. These data may be used to inform the development of evidence-based treatment guidelines; however, more studies are also needed to further evaluate the relative efficacy of these interventions. 

(C) 2014 Wiley Periodicals, Inc.
AD  - [Romanelli, Robert J.] Sutter Hlth, Clin Integrat Dept, Clin Outcomes Res, San Francisco, CA 94107 USA. [Wu, Frances M.] Sutter Hlth, Res Dev &amp; Disseminat, San Francisco, CA 94107 USA. [Gamba, Ryan] Univ Calif Berkeley, Berkeley, CA 94720 USA. [Mojtabai, Ramin] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mental Hlth, Baltimore, MD USA. [Segal, Jodi B.] Johns Hopkins Univ Sch Med, Dept Med, Baltimore, MD USA. Romanelli, RJ (reprint author), Sutter Hlth, Clin Integrat Dept, 7th Floor,633 Folsom St, San Francisco, CA 94107 USA. romanerj@sutterhealth.org
AN  - WOS:000340446600004
AU  - Romanelli,
AU  - R.
AU  - J.
AU  - Wu,
AU  - F.
AU  - M.
AU  - Gamba,
AU  - R.
AU  - Mojtabai,
AU  - R.
AU  - Segal,
AU  - J.
AU  - B.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/da.22232
J2  - Depress. Anxiety
KW  - obsessive-compulsive disorder behavioral therapy exposure and response/ritual prevention cognitive behavioral therapy serotonin-reuptake inhibitors pharmacotherapy meta-analysis systematic review CLINICAL-TRIAL PHARMACOLOGICAL-TREATMENTS FLUVOXAMINE CLO
L1  - internal-pdf://0565522282/Romanelli-2014-BEHAVIORAL THERAPY AND SEROTONI.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AN2WL Times Cited: 0 Cited Reference Count: 43 Romanelli, Robert J. Wu, Frances M. Gamba, Ryan Mojtabai, Ramin Segal, Jodi B. Segal, Jodi/A-2863-2009 Segal, Jodi/0000-0003-3978-9662 Lundbeck pharmaceuticals Conflict of interest: No funding was received for this study or the development of the manuscript. Dr. Mojtabai has received consulting fees from Lundbeck pharmaceuticals. Dr. Romanelli, Dr. Segal, Wu, and Gamba report no financial conflicts of interest. WILEY-BLACKWELL HOBOKEN DEPRESS ANXIETY
PY  - 2014
SP  - 641-652
T2  - Depression and Anxiety
TI  - Behavioral therapy and serotonin reuptake inhibitor pharmacotherapy in the treatment of obsessive-compulsive disorder: A systematic review and meta-analysis of head-to-head randomized controlled trials
UR  - &lt;Go to ISI&gt;://WOS:000340446600004http://onlinelibrary.wiley.com/store/10.1002/da.22232/asset/da22232.pdf?v=1&amp;t=ib7v96y8&amp;s=0fc687e35db8364a6e40627e5993ac97da1b2888
UR  - http://onlinelibrary.wiley.com/store/10.1002/da.22232/asset/da22232.pdf?v=1&amp;t=j8yfxp6v&amp;s=3d4359bbed117b702da880a93614f1617b9110f5
VL  - 31
ER  -
TY  - JOUR
AB  - **Objective **
To quantify the effects of parent- and family-based psychological therapies for youth with common chronic medical conditions on parent and family outcomes (primary aim) and child outcomes (secondary aim). 

**Methods **
MEDLINE, EMBASE, and PsycINFO were searched from inception to April 2013. 37 randomized controlled trials were included. Quality of the evidence was evaluated using GRADE criteria. Data were extracted on parent, family, and child outcomes. 

**Results**
Pooled psychological therapies had a positive effect on parent behavior at posttreatment and follow-up; no significant improvement was observed for other outcome domains. Problem-solving therapy (PST) improved parent mental health and parent behavior at posttreatment and follow-up. There was insufficient evidence to evaluate cognitive-behavioral and systems therapies for many outcome domains. 

**Conclusions **
Parent-and family-based psychological therapies can improve parent outcomes, with PST emerging as particularly promising. Future research should incorporate consensus statements for outcomes assessment, multisite recruitment, and active comparator conditions.
AD  - [Law, Emily F.; Fales, Jessica; Noel, Melanie] Seattle Childrens Res Inst, Ctr Child Hlth Behav &amp; Dev, Seattle, WA 98145 USA. [Law, Emily F.] Univ Washington, Dept Anesthesiol &amp; Pain Med, Sch Med, Seattle, WA 98195 USA. [Fisher, Emma; Eccleston, Christopher] Univ Bath, Ctr Pain Res, Bath BA2 7AY, Avon, England. Law, EF (reprint author), Seattle Childrens Res Inst, M-S CW8-6,POB 5371, Seattle, WA 98145 USA. emily.law@seattlechildrens.org
AN  - WOS:000343398100007
AU  - Law,
AU  - E.
AU  - E.
AU  - Fisher,
AU  - E.
AU  - Fales,
AU  - J.
AU  - Noel,
AU  - M.
AU  - Eccleston,
AU  - C.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1093/jpepsy/jsu032
J2  - J. Pediatr. Psychol.
KW  - asthma cancer cardiovascular disease children chronic illness chronic pain cystic fibrosis diabetes mellitus epilepsy family meta-analysis parent psychological therapies randomized controlled trials solid organ transplant spina bifida systematic review
L1  - internal-pdf://0169869262/Law-2014-Systematic Review and Meta-Analysis o.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AR2FD Times Cited: 1 Cited Reference Count: 88 Law, Emily F. Fisher, Emma Fales, Jessica Noel, Melanie Eccleston, Christopher 1 OXFORD UNIV PRESS INC CARY J PEDIATR PSYCHOL SI
PY  - 2014
SP  - 866-886
T2  - Journal of Pediatric Psychology
TI  - Systematic Review and Meta-Analysis of Parent and Family-Based Interventions for Children and Adolescents With Chronic Medical Conditions
UR  - &lt;Go to ISI&gt;://WOS:000343398100007http://jpepsy.oxfordjournals.org/content/39/8/866.longhttp://jpepsy.oxfordjournals.org/content/39/8/866.full.pdf
UR  - https://watermark.silverchair.com/jsu032.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAdswggHXBgkqhkiG9w0BBwagggHIMIIBxAIBADCCAb0GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMoB0QvyL_lBq0DGrwAgEQgIIBjiM-y08hFO02kYPGk8Tl4m_IMtsqS4BRvFdBU0dJLIKTgKwiV6kNZmxcjcesnlgBjuniFVfd_PUuNDmbao070PPZg5GKTOI9FStFLTeJGnT6mIBxG86ijfACCUF0jqOQrwDhh0NmOsiPhCDHlW2JfP6Ia7nJVUnVJZEByr6nt3O_NYNaPEb1qHT-4qxf7LLsIjUwK05vVwarSTwwjN08ZV4TkiIp6vGZAbWss6cMn4PkUVbEFf_zvJypSIwgCzt3jo5htPwsELg8lMuZ1XahapKY1YiNCP68gIqmBQW1fX7-539V4Knz6KUz_DqJPWlibJ9xpdS6GSA2Qflh28axln-JvxuC-GinNw3rvsNPWvgoC2dAg3Ep35vpNOylHfHZSZDehvqHRZ63w7xzxAnzgoM1-BaxyWWI9IgeDu7bxcrtwLZYmBObxmyvYMxW5kO-8bB44TebAERkB8nyPwYYdparZNtn2VQy8-ALFIcYA56bu8XAOTd5NdiZSiRHQjKwlFOgr2QXsBnw2simQdj3
VL  - 39
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Preventive interventions for adolescents are an important priority within school systems. Several interventions have been developed, but the effectiveness of such interventions varies considerably between studies. The purpose of this study was to assess the effectiveness of universal school-based prevention programs on alcohol use among adolescents by using meta-analytic techniques. 

**METHOD:** 
A systematic literature search in the databases, PubMed (Medline), PsycINFO (Ovid), EMBASE (Ovid) and WEB of Science (ISI) was conducted to search for empirical articles published in the period January 1990 to August 2014. 

**RESULTS: **
In total, 28 randomized controlled studies with 39,289 participants at baseline were included. Of these 28 articles, 12 studies (N=16279) reported continuous outcomes (frequency of alcohol use and quantity of alcohol use), and 16 studies (N=23010) reported categorical data (proportion of students who drank alcohol). The results of the random effects analyses showed that the overall effect size among studies reporting continuous outcomes was small and demonstrated a favorable effect from the preventive interventions (Hedges&#039; g = 0.22, p&lt;.01). The effect size among studies reporting categorical outcomes was not significant (OR = 0.94, p=.25). The level of heterogeneity between studies was found to be significant in most analyses. Moderator analyses conducted to explore the heterogeneity showed neither significant difference between the different school levels (junior high schools and high schools), nor between the varied program intensities (low, medium and high intensity programs). The meta-regression analyses examining continuous moderators showed no significant effects for age or gender. 

**CONCLUSIONS: **
The findings from this meta-analysis showed that, overall, the effects of school-based preventive alcohol interventions on adolescent alcohol use were small but positive among studies reporting the continuous measures, whereas no effect was found among studies reporting the categorical outcomes. Possible population health outcomes, with recommendations for policy and practice, are discussed further in this paper.
AD  - Strom,Henriette Kyrrestad. Regional Centre for Child and Youth Mental Health and Child Welfare, Faculty of Health Sciences, UiT The Arctic University of Norway, 9037 Tromso, Norway. Henriette.Kyrrestad@uit.no.
AN  - 25495012
AU  - Strom,
AU  - H.
AU  - K.
AU  - Adolfsen,
AU  - F.
AU  - Fossum,
AU  - S.
AU  - Kaiser,
AU  - S.
AU  - Martinussen,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/1747-597X-9-48
DP  - Ovid Technologies
J2  - Subst Abuse Treat Prev Policy
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Strom, Henriette Kyrrestad Adolfsen, Frode Fossum, Sturla Kaiser, Sabine Martinussen, Monica
PY  - 2014
SP  - 48
T2  - Substance Abuse Treatment, Prevention, &amp; Policy
TI  - Effectiveness of school-based preventive interventions on adolescent alcohol use: a meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25495012 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25495012&amp;id=doi:10.1186%2F1747-597X-9-48&amp;issn=1747-597X&amp;isbn=&amp;volume=9&amp;issue=&amp;spage=48&amp;pages=48&amp;date=2014&amp;title=Substance+Abuse+Treatment%2C+Prevention%2C+%26+Policy&amp;atitle=Effectiveness+of+school-based+preventive+interventions+on+adolescent+alcohol+use%3A+a+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Strom&amp;pid=%3Cauthor%3EStrom+HK%3C%2Fauthor%3E%3CAN%3E25495012%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.substanceabusepolicy.com/content/pdf/1747-597X-9-48.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - Foster children experience a lot of stress because of their life histories and changes in their family circumstances, such as foster care placement. It is important that foster parents recognize the early signs of stress in foster children and learn how to act in a non-threatening and understanding manner. 

Family-based interventions may help in this. In this paper, we report on a meta-analysis of studies (n = 19) of the effectiveness of such interventions. All studies used a pre-test/post-test design. 

Both problem behaviour in foster children and the parenting skills of foster parents improved by 30%; however, none of the interventions were specifically intended to help young children (&lt;4 years) to cope with stress. 

The importance of interventions for young foster children is discussed, as well as the necessary elements these interventions should include. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - H Van Andel, Hans W. H.: h.vanandel@dimence.nl Van Andel, Hans W. H.: Department of Child and Adolescent Psychiatry and Developmental Disorders, GGZ Dimence, Pikeursbaan 3, Deventer, Netherlands, 7411GT, h.vanandel@dimence.nl Van Andel, Hans W. H.: Department of Child and Adolescent Psychiatry and Developmental Disorders, GGZ Dimence, Deventer, Netherlands Grietens, Hans: Centre for Special Needs Education and Youth Care, University of Groningen, Groningen, Netherlands Strijker, Johan: Centre for Special Needs Education and Youth Care, University of Groningen, Groningen, Netherlands Van der Gaag, Rutger J.: University Medical Centre St. Radboud, Nijmegen, Netherlands Knorth, Erik J.: Centre for Special Needs Education and Youth Care, University of Groningen, Groningen, Netherlands
AN  - 2014-07022-003
AU  - Van
AU  - Andel,
AU  - H.
AU  - W.
AU  - Grietens,
AU  - H.
AU  - Strijker,
AU  - J.
AU  - Van
AU  - der
AU  - Gaag,
AU  - R.
AU  - J.
AU  - Knorth,
AU  - E.
AU  - J.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1365-2206.2012.00885.x
DP  - Ovid Technologies
KW  - effective interventions, foster care, family circumstances, stress, foster children *Foster Care *Foster Children *Intervention Family Stress Community &amp; Social Services [3373] Human Childhood (birth-12 yrs)
LA  - English
M3  - Meta Analysis
PY  - 2014
SP  - 149-155
T2  - Child &amp; Family Social Work
TI  - Searching for effective interventions for foster children under stress: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2014-07022-003 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1111%2Fj.1365-2206.2012.00885.x&amp;issn=1356-7500&amp;isbn=&amp;volume=19&amp;issue=2&amp;spage=149&amp;pages=149-155&amp;date=2014&amp;title=Child+%26+Family+Social+Work&amp;atitle=Searching+for+effective+interventions+for+foster+children+under+stress%3A+A+meta-analysis.&amp;aulast=Van+Andel&amp;pid=%3Cauthor%3EVan+Andel%2C+Hans+W.+H%3C%2Fauthor%3E%3CAN%3E2014-07022-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1365-2206.2012.00885.x/asset/cfs885.pdf?v=1&amp;t=ib7nefxe&amp;s=50aeff565ce494ec386021e25addd2fdf6e22db4
VL  - 19
ER  -
TY  - JOUR
AB  - This meta-analysis of clinical trials explored the effectiveness of treatments targeted at changing oppositional behavior. 

The meta-analysis included 31 peer-reviewed treatment studies with school-age youth ages 6-17 years identified as having oppositional defiant disorder. 

Results were synthesized using a random effects model for mean difference and mean gain effect size estimates. 

Findings suggest that counseling/psychotherapy is effective in treating oppositional behavior in school-age youth at termination, but the long-term efficacy of such treatment is less stable.
AD  - [Erford, Bradley T.; Paul, Lauren E.; Oncken, Conor] Loyola Univ Maryland, Educ Specialties Dept, Lutherville Timonium, MD 21093 USA. [Kress, Victoria E.] Youngstown State Univ, Dept Counseling &amp; Special Educ, Youngstown, OH 44555 USA. [Erford, Matthew R.] Susquehanna Univ, Dept Psychol, Selinsgrove, PA 17870 USA. Erford, BT (reprint author), Loyola Univ Maryland, Educ Specialties Dept, Timonium Grad Ctr, 2034 Greenspring Dr, Lutherville Timonium, MD 21093 USA. berford@loyola.edu
AN  - WOS:000329323500002
AU  - Erford,
AU  - B.
AU  - T.
AU  - Paul,
AU  - L.
AU  - E.
AU  - Oncken,
AU  - C.
AU  - Kress,
AU  - V.
AU  - E.
AU  - Erford,
AU  - M.
AU  - R.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/j.1556-6676.2014.00125.x
J2  - J. Couns. Dev.
KW  - oppositional behavior oppositional defiant disorder counseling psychotherapy RANDOMIZED CONTROLLED-TRIAL CHILD INTERACTION THERAPY ONSET CONDUCT PROBLEMS DEFIANT DISORDER INTERVENTION PROGRAM DISRUPTIVE BEHAVIOR ANTISOCIAL-BEHAVIOR TREATING CHILDREN TRA
L1  - internal-pdf://0452558773/Erford-2014-Counseling Outcomes for Youth With.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 284MR Times Cited: 0 Cited Reference Count: 65 Erford, Bradley T. Paul, Lauren E. Oncken, Conor Kress, Victoria E. Erford, Matthew R. WILEY-BLACKWELL HOBOKEN J COUNS DEV
PY  - 2014
SP  - 13-24
T2  - Journal of Counseling and Development
TI  - Counseling Outcomes for Youth With Oppositional Behavior: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000329323500002http://onlinelibrary.wiley.com/store/10.1002/j.1556-6676.2014.00125.x/asset/jcad125.pdf?v=1&amp;t=ib3i0w26&amp;s=1ce72d08745d2e871d9ebe6eb72b6a25aeda25ff
UR  - http://onlinelibrary.wiley.com/store/10.1002/j.1556-6676.2014.00125.x/asset/jcad125.pdf?v=1&amp;t=j8yeuurr&amp;s=2444f669f54dfb26ef046ff13da45a7957f5446e
VL  - 92
ER  -
TY  - JOUR
AB  - Despite high comorbidity rates and potential clinical implications, the influence of co-occurring attention-deficit/hyperactivity disorder (ADHD) on outcomes of cognitive-behavioral treatment (CBT) for anxious youth remains poorly understood. 

In this qualitative review, the current literature on the influence of comorbid ADHD on CBT of youth with diverse anxiety disorders is explored. Peer-reviewed studies examining ADHD, at the diagnostic and symptom level, received highest priority. In addition, inasmuch as some studies did not isolate the effects of ADHD from other disruptive behavior disorders (DBDs: oppositional defiant disorder, conduct disorders), studies with the three DBDs were explored as well. Ten studies met our specified methodological criteria. 

Findings are discussed in relation to the following two factors: type of anxiety disorder and measurement of ADHD (diagnostic or symptom level) in these studies. There was evidence that youth with a variety of anxiety disorders and with co-occurring ADHD fared worse than their counterparts without ADHD. 

Additionally, grouping ADHD with other DBDs tended to obscure the negative impact of ADHD on treatment outcomes. Additional research is needed to delineate the influence of comorbid ADHD specifically on treatment outcomes for the various anxiety disorders. Clinical implications of treating anxious youth with comorbid ADHD are explored. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Halldorsdottir, Thorhildur: thorhh1@vt.edu Halldorsdottir, Thorhildur: Virginia Polytechnic Institute and State University, Child Study Center, 460 Turner Street, Suite 207, Blacksburg, VA, US, 24060, thorhh1@vt.edu Halldorsdottir, Thorhildur: Virginia Polytechnic Institute and State University, Blacksburg, VA, US Ollendick, Thomas H.: Virginia Polytechnic Institute and State University, Blacksburg, VA, US
AN  - 2013-35475-001
AU  - Halldorsdottir,
AU  - T.
AU  - Ollendick,
AU  - T.
AU  - H.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.cbpra.2013.08.003
DP  - Ovid Technologies
KW  - anxiety disorders, disruptive behavior disorders, attention deficit disorder with hyperactivity, treatment *Anxiety Disorders *Attention Deficit Disorder with Hyperactivity *Behavior Disorders *Treatment Adolescent Development Childhood Development Psyc
LA  - English
M3  - Literature Review; Meta Analysis
PY  - 2014
SP  - 310-322
T2  - Cognitive and Behavioral Practice
TI  - Comorbid ADHD: Implications for the treatment of anxiety disorders in children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-35475-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.cbpra.2013.08.003&amp;issn=1077-7229&amp;isbn=&amp;volume=21&amp;issue=3&amp;spage=310&amp;pages=310-322&amp;date=2014&amp;title=Cognitive+and+Behavioral+Practice&amp;atitle=Comorbid+ADHD%3A+Implications+for+the+treatment+of+anxiety+disorders+in+children+and+adolescents.&amp;aulast=Halldorsdottir&amp;pid=%3Cauthor%3EHalldorsdottir%2C+Thorhildur%3C%2Fauthor%3E%3CAN%3E2013-35475-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1077722913000679/1-s2.0-S1077722913000679-main.pdf?_tid=59b52194-1981-11e5-999c-00000aacb35f&amp;acdnat=1435048085_45da8a7ff06476c237b627e321bc466d
VL  - 21
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
This systematic review and meta-analysis examined the effects of psychological therapies for management of chronic pain in children. 

**METHODS: **
Randomized controlled trials of psychological interventions treating children (&lt;18 years) with chronic pain conditions including headache, abdominal, musculoskeletal, or neuropathic pain were searched for. Pain symptoms, disability, depression, anxiety, and sleep outcomes were extracted. Risk of bias was assessed and quality of the evidence was rated using GRADE. 

**RESULTS: **
35 included studies revealed that across all chronic pain conditions, psychological interventions reduced pain symptoms and disability posttreatment. Individual pain conditions were analyzed separately. Sleep outcomes were not reported in any trials. Optimal dose of treatment was explored. For headache pain, higher treatment dose led to greater reductions in pain. No effect of dosage was found for other chronic pain conditions. 

**CONCLUSIONS: **
Evidence for psychological therapies treating chronic pain is promising. Recommendations for clinical practice and research are presented.

Copyright &copy; The Author 2014. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. 

All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
AD  - Fisher,Emma. Centre for Pain Research, University of Bath, Department of Experimental Psychology, University of Oxford, Department of Anaesthesiology &amp; Pain Medicine, University of Washington, Clinical Health Psychology, University College London, and University College London Hospitals, and Psychology Department, Kings College London e.a.fisher@bath.ac.uk. Heathcote,Lauren. Centre for Pain Research, University of Bath, Department of Experimental Psychology, University of Oxford, Department of Anaesthesiology &amp; Pain Medicine, University of Washington, Clinical Health Psychology, University College London, and University College London Hospitals, and Psychology Department, Kings College London. Palermo,Tonya M. Centre for Pain Research, University of Bath, Department of Experimental Psychology, University of Oxford, Department of Anaesthesiology &amp; Pain Medicine, University of Washington, Clinical Health Psychology, University College London, and University College London Hospitals, and Psychology Department, Kings College London. de C Williams,Amanda C. Centre for Pain Research, University of Bath, Department of Experimental Psychology, University of Oxford, Department of Anaesthesiology &amp; Pain Medicine, University of Washington, Clinical Health Psychology, University College London, and University College London Hospitals, and Psychology Department, Kings College London. Lau,Jennifer. Centre for Pain Research, University of Bath, Department of Experimental Psychology, University of Oxford, Department of Anaesthesiology &amp; Pain Medicine, University of Washington, Clinical Health Psychology, University College London, and University College London Hospitals, and Psychology Department, Kings College London. Eccleston,Christopher. Centre for Pain Research, University of Bath, Department of Experimental Psychology, University of Oxford, Department of Anaesthesiology &amp; Pain Medicine, University of Washington, Clinical Health Psychology, University College London, and University College London Hospitals, and Psychology Department, Kings College London.
AN  - 24602890
AU  - Fisher,
AU  - E.
AU  - Heathcote,
AU  - L.
AU  - Palermo,
AU  - T.
AU  - M.
AU  - Williams
AU  - A.
AU  - C.
AU  - de,
AU  - C.
AU  - Lau,
AU  - J.
AU  - Eccleston,
AU  - C.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1093/jpepsy/jsu008
DP  - Ovid Technologies
J2  - J Pediatr Psychol
L1  - internal-pdf://0761431982/Fisher-2014-Systematic review and meta-analysi.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Fisher, Emma Heathcote, Lauren Palermo, Tonya M de C Williams, Amanda C Lau, Jennifer Eccleston, Christopher K24 HD060068 (United States NICHD NIH HHS)
PY  - 2014
SP  - 763-82
T2  - Journal of Pediatric Psychology
TI  - Systematic review and meta-analysis of psychological therapies for children with chronic pain
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24602890 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24602890&amp;id=doi:10.1093%2Fjpepsy%2Fjsu008&amp;issn=0146-8693&amp;isbn=&amp;volume=39&amp;issue=8&amp;spage=763&amp;pages=763-82&amp;date=2014&amp;title=Journal+of+Pediatric+Psychology&amp;atitle=Systematic+review+and+meta-analysis+of+psychological+therapies+for+children+with+chronic+pain.&amp;aulast=Fisher&amp;pid=%3Cauthor%3EFisher+E%3C%2Fauthor%3E%3CAN%3E24602890%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://jpepsy.oxfordjournals.org/content/39/8/763.longhttp://jpepsy.oxfordjournals.org/content/39/8/763.full.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148613/pdf/jsu008.pdf
VL  - 39
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Behavioral interventions are recommended as attention-deficit/hyperactivity disorder (ADHD) treatments. However, a recent meta-analysis found no effects on core ADHD symptoms when raters were probably blind to treatment allocation. The present analysis is extended to a broader range of child and parent outcomes. 

**METHOD: **
A systematic search in PubMed, Ovid, Web of Knowledge, ERIC, and CINAHAL databases (up to February 5, 2013) identified published randomized controlled trials measuring a range of patient and parent outcomes for children and adolescents diagnosed with ADHD (or who met validated cutoffs on rating scales). 

**RESULTS: **
Thirty-two of 2,057 nonduplicate screened records were analyzed. For assessments made by individuals closest to the treatment setting (usually unblinded), there were significant improvements in parenting quality (standardized mean difference [SMD] for positive parenting 0.68; SMD for negative parenting 0.57), parenting self-concept (SMD 0.37), and child ADHD (SMD 0.35), conduct problems (SMD 0.26), social skills (SMD 0.47), and academic performance (SMD 0.28). With probably blinded assessments, significant effects persisted for parenting (SMD for positive parenting 0.63; SMD for negative parenting 0.43) and conduct problems (SMD 0.31). 

**CONCLUSION: **
In contrast to the lack of blinded evidence of ADHD symptom decrease, behavioral interventions have positive effects on a range of other outcomes when used with patients with ADHD. There is blinded evidence that they improve parenting and decrease childhood conduct problems. These effects also may feed through into a more positive parenting self-concept but not improved parent mental well-being.

Copyright &copy; 2014 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
AD  - Daley,David. School of Medicine, University of Nottingham, UK, and the Centre for ADHD and Neurodevelopmental Disorders Across the Lifespan, Institute of Mental Health, University of Nottingham. Electronic address: David.Daley@nottingham.ac.uk. van der Oord,Saskia. KU Leuven, Belgium, and the University of Amsterdam, the Netherlands. Ferrin,Maite. Kings College London, Institute of Psychiatry, UK, and the Centro de Salud Mental de Estella, Navarra, Spain. Danckaerts,Marina. KU Leuven. Doepfner,Manfred. School of Medicine, University of Cologne, Germany. Cortese,Samuele. Cambridgeshire and Peterborough Foundation Trust, and the School of Medicine and the Centre for ADHD and Neurodevelopmental Disorders Across the Lifespan, Institute of Mental Health, University of Nottingham. Sonuga-Barke,Edmund J S. Developmental Brain-Behaviour Laboratory, Psychology, University of Southampton, UK; Ghent University, Belgium; and Aarhus University, Denmark. Electronic address: ejb3@soton.ac.uk.
AN  - 25062591
AU  - Daley,
AU  - D.
AU  - van
AU  - der
AU  - Oord,
AU  - S.
AU  - Ferrin,
AU  - M.
AU  - Danckaerts,
AU  - M.
AU  - Doepfner,
AU  - M.
AU  - Cortese,
AU  - S.
AU  - Sonuga-Barke,
AU  - E.
AU  - J.
AU  - European
AU  - ADHD
AU  - Guidelines
AU  - Group
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2014.05.013
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
LA  - English
M3  - Review
N1  - Daley, David van der Oord, Saskia Ferrin, Maite Danckaerts, Marina Doepfner, Manfred Cortese, Samuele Sonuga-Barke, Edmund J S European ADHD Guidelines Group Banaschewski T Buitelaar J Brandeis D Coghil D Cortese S Daley D Danckaerts M Dittmann RW Dopfner M Ferrin M Graham J Hollis C Holtmann M Lecendreux M Konofal E Santosh P Rothenberger A Sergeant JA Simonoff E Sonuga-Barke EJ Steinhausen HC Stevenson J Stringaris A Taylor E Thompson M van der Oord S Wong I Zuddas A Comment in: J Am Acad Child Adolesc Psychiatry. 2014 Aug;53(8):830-2; PMID: 25062589 S0890-8567(14)00408-0
PY  - 2014
SP  - 835-47, 847.e1-5
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Behavioral interventions in attention-deficit/hyperactivity disorder: a meta-analysis of randomized controlled trials across multiple outcome domains
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25062591
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25062591&amp;id=doi:10.1016%2Fj.jaac.2014.05.013&amp;issn=0890-8567&amp;isbn=&amp;volume=53&amp;issue=8&amp;spage=835&amp;pages=835-47%2C+847.e1-5&amp;date=2014&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Behavioral+interventions+in+attention-deficit%2Fhyperactivity+disorder%3A+a+meta-analysis+of+randomized+controlled+trials+across+multiple+outcome+domains.&amp;aulast=Daley&amp;pid=%3Cauthor%3EDaley+D%3C%2Fauthor%3E%3CAN%3E25062591%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0890856714004080/1-s2.0-S0890856714004080-main.pdf?_tid=f6b0b15e-1673-11e5-bc35-00000aab0f6c&amp;acdnat=1434712482_67019b88102e7fc956580118a6198a5b
VL  - 53
ER  -
TY  - JOUR
AB  - **Background:** 
Attention deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder of childhood onset, which may persist into adulthood. ADHD has a significant impact on a child&#039;s daily life, affecting relationships and academic performance. Its core symptoms include developmentally inappropriate levels of inattention, hyperactivity, and impulsive behaviour. Tricyclic antidepressants (TCAs) are sometimes used as second line of treatment in the reduction of ADHD symptoms in children and adolescents with ADHD. However, their efficacy is not yet known.

**Objectives:**
To assess the efficacy of TCAs in the reduction of ADHD symptoms within the broad categories of hyperactivity, impulsivity, and inattentiveness in young people aged 6 to 18 years with established diagnoses of ADHD.

**Search methods:** 
On 26 September 2013, we searched CENTRAL, Ovid MEDLINE, Embase, PsycINFO, CINAHL, seven other databases, and two trials registers. We also searched the reference lists of relevant articles, and contacted manufacturers and known experts in the field to determine if there were any ongoing trials or unpublished studies available.

**Selection criteria:** 
Randomised controlled trials (RCTs), including both parallel group and cross-over study designs, of any dose of TCA compared with placebo or active medication in children or adolescents with ADHD, including those with comorbid conditions.&nbsp;

**Data collection and analysis:** 
Working in pairs, three review authors independently screened records, extracted data, and assessed trial quality. We calculated the standardised mean differences (SMD) for continuous data, the odds ratio (OR) for dichotomous data, and 95% confidence intervals (CIs) for both. We conducted the meta-analyses using a random-effects model throughout. We used the Cochrane &#039;Risk of bias&#039; tool to assess the risk of bias of each included trial and the GRADE approach to assess the quality of the body evidence.

**Main results:** 
We included six RCTs with a total of 216 participants. Five of the six trials compared desipramine with placebo; the remaining trial compared nortriptyline with placebo. One trial compared desipramine with clonidine and placebo, and another compared two TCAs (desipramine and clomipramine) with methylphenidate and placebo. Of the six trials, one RCT primarily assessed the efficacy of TCA in children with ADHD and comorbid tic or Tourette disorder, and another one trial was in children with comorbid tic disorder. RCTs that met our inclusion criteria varied both in design and quality, and none were free of bias. The quality of the evidence was low to very low according to our GRADE assessments.TCA outperformed placebo regarding the proportions of patients achieving a predefined improvement of core ADHD symptom severity (OR 18.50, 95% CI 6.29 to 54.39, 3 trials, 125 participants, low quality evidence). In particular, there was evidence that desipramine improved the core symptoms of ADHD in children and adolescents as assessed by parents (SMD -1.42, 95% CI -1.99 to -0.85, 2 trials, 99 participants, low quality evidence), teachers (SMD -0.97, 95% CI -1.66 to -0.28, 2 trials, 89 participants, low quality evidence), and clinicians (OR 26.41, 95% CI 7.41 to 94.18, 2 trials, 103 participants, low quality evidence). Nortriptryline was also efficacious in improving the core symptoms of ADHD in children and adolescents as assessed by clinicians (OR 7.88, 95% CI 1.10 to 56.12). Desipramine and placebo were similar on &quot;all-cause treatment discontinuation&quot; (RD -0.10, 95% CI -0.25 to 0.04, 3 trials, 134 participants, very low quality evidence). Desipramine appeared more efficacious than clonidine in reducing ADHD symptoms as rated by parents (SMD -0.90, 95% CI -1.40 to -0.40, 1 trial, 68 participants, very low quality evidence) in participants with ADHD and comorbid tics or Tourette syndrome. Although this Cochrane Review did not identify serious adverse effects in patients taking TCAs, it did identify mild increases in diastolic blood pressure and pulse rates. Also, patients treated with desipramine had significantl igher rates of appetite suppression compared to placebo whilst nortriptyline resulted in weight gain. Other reported adverse effects included headache, confusion, sedation, tiredness, blurred vision, diaphoresis, dry mouth, abdominal discomfort, constipation, and urinary retention.

**Authors&#039; conclusions:** 
Most evidence on TCAs relates to desipramine. Findings suggest that, in the short term, desipramine improves the core symptoms of ADHD, but its effect on the cardiovascular system remains an important clinical concern. Thus, evidence supporting the clinical use of desipramine for the treatment of children with ADHD is low.
AN  - CD006997
AU  - Otasowie,
AU  - J.
AU  - Castells,
AU  - X.
AU  - Ehimare,
AU  - U.
AU  - P.
AU  - Smith,
AU  - C.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd006997.pub2
KW  - Antidepressive Agents, Tricyclic [therapeutic use]
KW  - Attention Deficit Disorder with Hyperactivity [drug therapy]
KW  - Central Nervous System Stimulants [therapeutic use]
KW  - Clonidine [therapeutic use]
KW  - Desipramine [therapeutic use]
KW  - Methylphenidate [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Tic Disorders [drug therapy]
KW  - Tourette Syndrome [drug therapy]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2014
T2  - Cochrane Database of Systematic Reviews
TI  - Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006997.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006997.pub2/asset/CD006997.pdf?v=1&amp;t=iw7lbx7w&amp;s=9320033073bffc2754556e08d06ac219cb59ea12
ER  -
TY  - JOUR
AB  - **Background:** 
Depressive disorders are common in children and adolescents and, if left untreated, are likely to recur in adulthood. Depression is highly debilitating, affecting psychosocial, family and academic functioning.

**Objectives:** 
To evaluate the effectiveness of psychological therapies and antidepressant medication, alone and in combination, for the treatment of depressive disorder in children and adolescents. We have examined clinical outcomes including remission, clinician and self reported depression measures, and suicide-related outcomes.

**Search methods:** 
We searched the Cochrane Depression, Anxiety and Neurosis Review Group&#039;s Specialised Register (CCDANCTR) to 11 June 2014. The register contains reports of relevant randomised controlled trials (RCTs) from the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (1950 to date), EMBASE (1974 to date), and PsycINFO (1967 to date).

**Selection criteria:**
RCTs were eligible for inclusion if they compared i) any psychological therapy with any antidepressant medication, or ii) a combination of psychological therapy and antidepressant medication with a psychological therapy alone, or an antidepressant medication alone, or iii) a combination of psychological therapy and antidepressant medication with a placebo or&#039;treatment as usual&#039;, or (iv) a combination of psychological therapy and antidepressant medication with a psychological therapy or antidepressant medication plus a placebo.We included studies if they involved participants aged between 6 and 18 years, diagnosed by a clinician as having Major Depressive Disorder (MDD) based on Diagnostic and Statistical Manual (DSM) or International Classification of Diseases (ICD) criteria.

**Data collection and analysis:** 
Two review authors independently selected studies, extracted data and assessed the quality of the studies. We applied a random-effects meta-analysis, using the odds ratio (OR) to describe dichotomous outcomes, mean difference (MD) to describe continuous outcomes when the same measures were used, and standard mean difference (SMD) when outcomes were measured on different scales.

**Main results:** 
We included eleven studies, involving 1307 participants in this review. We also identified one ongoing study, and two additional ongoing studies that may be eligible for inclusion. Studies recruited participants with different severities of disorder and with a variety of comorbid disorders, including anxiety and substance use disorder, therefore limiting the comparability of the results. Regarding the risk of bias in studies, just under half the studies had adequate allocation concealment (there was insufficient information to determine allocation concealment in the remainder), outcome assessors were blind to the participants&#039; intervention in six studies, and in general, studies reported on incomplete data analysis methods, mainly using intention-to-treat (ITT) analyses. For the majority of outcomes there were no statistically significant differences between the interventions compared. There was limited evidence (based on two studies involving 220 participants) that antidepressant medication was more effective than psychotherapy on measures of clinician defined remission immediately post-intervention (odds ratio (OR) 0.52, 95% confidence interval (CI) 0.27 to 0.98), with 67.8% of participants in the medication group and 53.7% in the psychotherapy group rated as being in remission. There was limited evidence (based on three studies involving 378 participants) that combination therapy was more effective than antidepressant medication alone in achieving higher remission from a depressive episode immediately post-intervention (OR 1.56, 95% CI 0.98 to 2.47), with 65.9% of participants treated with combination therapy and 57.8% of participants treated with medication, rated as being in remission. There was no evidence to suggest that combination therapy was more effective than psychological therapy alone, based on clinician rated remission immediately post-intervention (OR 1.82, 95% CI 0.38 to 8.68).Suicide-related Serious d erse Events (SAEs) were reported in various ways across studies and could not be combined in meta-analyses. However, some trials measured suicidal ideation using standardised assessment tools suitable for meta-analysis. In one study involving 188 participants, rates of suicidal ideation were significantly higher in the antidepressant medication group (18.6%) compared with the psychological therapy group (5.4%) (OR 0.26, 95% CI 0.09 to 0.72) and this effect appeared to remain at six to nine months (OR 0.26, 95% CI 0.07 to 0.98), with 13.6% of participants in the medication group and 3.9% of participants in the psychological therapy group reporting suicidal ideation. It was unclear what the effect of combination therapy was compared with either antidepressant medication alone or psychological therapy alone on rates of suicidal ideation. The impact of any of the assigned treatment packages on drop out was also mostly unclear across the various comparisons in the review.Limited data and conflicting results based on other outcome measures make it difficult to draw conclusions regarding the effectiveness of any specific intervention based on these outcomes.

**Authors&#039; conclusions:** 
There is very limited evidence upon which to base conclusions about the relative effectiveness of psychological interventions, antidepressant medication and a combination of these interventions. On the basis of the available evidence, the effectiveness of these interventions for treating depressive disorders in children and adolescents cannot be established. Further appropriately powered RCTs are required.
AN  - CD008324
AU  - Cox,
AU  - G.
AU  - R.
AU  - Callahan,
AU  - P.
AU  - Churchill,
AU  - R.
AU  - Hunot,
AU  - V.
AU  - Merry,
AU  - S.
AU  - N.
AU  - Parker,
AU  - A.
AU  - G.
AU  - Hetrick,
AU  - S.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd008324.pub3
KW  - Antidepressive Agents [therapeutic use]
KW  - Anxiety [therapy]
KW  - Combined Modality Therapy [methods]
KW  - Depressive Disorder, Major [therapy]
KW  - Psychotherapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Substance-Related Disorders [therapy]
KW  - Suicidal Ideation
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2014
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological therapies versus antidepressant medication, alone and in combination for depression in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008324.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD008324.pub3/asset/CD008324.pdf?v=1&amp;t=iw7kuwuu&amp;s=4cf36735180dbf555a6b27f98a97224eef1c3a83
ER  -
TY  - JOUR
AB  - **Background: **
Research for effective psychological interventions for refugee and asylum-seeking children has intensified. The need for interventions in environments more easily accessed by children and families is especially relevant for newly arrived populations. This paper reviews the literature on school and community-based interventions aimed at reducing psychological disorders in refugee and asylum-seeking children. 

**Methods and Findings:**
Comprehensive searches were conducted in seven databases and further information was obtained through searching reference lists, grey literature, and contacting experts in the field. Studies were included if they reported on the efficacy of a school or community-based mental health intervention for refugee or asylum-seeking children. Two independent reviewers made the final study selection, extracted data, and reached consensus on study quality. Results were summarized descriptively. The marked heterogeneity of studies excluded conducting a meta-analysis but study effect-sizes were calculated where possible. Twenty one studies met inclusion criteria for the review reporting on interventions for approximately 1800 refugee children. Fourteen studies were carried out in high-income countries in either a school (n = 11) or community (n = 3) setting and seven studies were carried out in refugee camps. Interventions were either primarily focused on the verbal processing of past experiences (n = 9), or on an array of creative art techniques (n = 7) and others used a combination of these interventions (n = 5). While both intervention types reported significant changes in symptomatology, effect sizes ranged from 0.31 to 0.93 and could mainly be calculated for interventions focusing on the verbal processing of past experiences. 

**Conclusions: **
Only a small number of studies fulfilled inclusion criteria and the majority of these were in the school setting. The findings suggest that interventions delivered within the school setting can be successful in helping children overcome difficulties associated with forced migration.
AD  - [Tyrer, Rebecca A.; Fazel, Mina] Univ Oxford, Warneford Hosp, Dept Psychiat, Oxford, England. Fazel, M (reprint author), Univ Oxford, Warneford Hosp, Dept Psychiat, Oxford, England. mina.fazel@psych.ox.ac.uk
AN  - WOS:000331880700030
AU  - Tyrer,
AU  - R.
AU  - A.
AU  - Fazel,
AU  - M.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0089359
J2  - PLoS One
KW  - POSTTRAUMATIC-STRESS-DISORDER CREATIVE EXPRESSION WORKSHOPS RANDOMIZED CONTROLLED-TRIAL MENTAL-HEALTH INTERVENTION MIDDLE-INCOME COUNTRIES NORTHERN UGANDA IMMIGRANT CHILDREN PROTECTIVE FACTORS EXPOSURE THERAPY SRI-LANKA Multidisciplinary Sciences
L1  - internal-pdf://2995411438/Tyrer-2014-School and Community-Based Interven.PDF
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AB6EP Times Cited: 2 Cited Reference Count: 72 Tyrer, Rebecca A. Fazel, Mina NIHR Post-Doctoral Fellowship [PDF-2010-03-10] This study was funded by a NIHR Post-Doctoral Fellowship for MF (PDF-2010-03-10). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. 2 PUBLIC LIBRARY SCIENCE SAN FRANCISCO PLOS ONE
PY  - 2014
SP  - 10
T2  - Plos One
TI  - School and Community-Based Interventions for Refugee and Asylum Seeking Children: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000331880700030http://www.plosone.org/article/fetchObject.action?uri=info:doi/10.1371/journal.pone.0089359&amp;representation=PDF
VL  - 9
ER  -
TY  - JOUR
AB  - **Background **
Multiple treatments exist for fecal incontinence. However, the relative and additive influence of commonly used behavioral approaches remains unclear. 

**Objective **
We conducted a systematic review of randomized controlled trials to synthesize the effects of behavioral treatment of fecal incontinence with constipation in children aged 4-18 years. Mixed treatment comparisons (MTCs) and random effects models were used to analyze outcomes. Risk of bias and quality of evidence were rated. 

**Results**
Although 10 studies were identified for MTCs, results did not yield reliable or valid estimates. Four studies were retained for random effects pooled outcome analysis. Results indicated that behavioral intervention was more effective than control conditions for author-defined success and soiling frequency. 

**Conclusion **
Although evidence supports behavioral treatments for fecal incontinence with constipation in children, available evidence is limited. More and higher-quality trials are needed to better understand the relative effects of different treatments, including behavioral strategies.
AD  - [Freeman, Kurt A.; Riley, Andrew; Duke, Danny C.] Oregon Hlth &amp; Sci Univ, Div Psychol, Inst Dev &amp; Disabil, Portland, OR 97239 USA. [Fu, Rongwei] Oregon Hlth &amp; Sci Univ, Dept Publ Hlth &amp; Preventat Med, Portland, OR 97239 USA. Freeman, KA (reprint author), Oregon Hlth &amp; Sci Univ, 707 SW Gaines, Portland, OR 97239 USA. freemaku@ohsu.edu
AN  - WOS:000343398100008
AU  - Freeman,
AU  - K.
AU  - A.
AU  - Riley,
AU  - A.
AU  - Duke,
AU  - D.
AU  - C.
AU  - Fu,
AU  - R.
AU  - W.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1093/jpepsy/jsu039
J2  - J. Pediatr. Psychol.
KW  - encopresis evidence-based practice fecal incontinence meta-analysis systematic review ABNORMAL DEFECATION DYNAMICS RANDOMIZED CONTROLLED-TRIALS STOOL-TOILETING REFUSAL CHILDHOOD CONSTIPATION ENCOPRETIC CHILDREN PEDIATRIC ENCOPRESIS STIMULUS-CONTROL DIET
L1  - internal-pdf://0367271772/Freeman-2014-Systematic Review and Meta-Analys.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AR2FD Times Cited: 1 Cited Reference Count: 64 Freeman, Kurt A. Riley, Andrew Duke, Danny C. Fu, Rongwei 1 OXFORD UNIV PRESS INC CARY J PEDIATR PSYCHOL SI
PY  - 2014
SP  - 887-902
T2  - Journal of Pediatric Psychology
TI  - Systematic Review and Meta-Analysis of Behavioral Interventions for Fecal Incontinence With Constipation
UR  - &lt;Go to ISI&gt;://WOS:000343398100008http://jpepsy.oxfordjournals.org/content/39/8/887.longhttp://jpepsy.oxfordjournals.org/content/39/8/887.full.pdf
UR  - https://watermark.silverchair.com/jsu039.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAdswggHXBgkqhkiG9w0BBwagggHIMIIBxAIBADCCAb0GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMjInJI5P62w4xX3NTAgEQgIIBjonKS_Jr-9p2DO-GxAZ_A-3wd6UUr0IYfD-XWKC3DzMBirGGipNlhemlOvyPjbwg23XNvwxg9e4effUfzGL0S2cjUtDewz5zzTaisRfp_Hn4fg_rH73wbWjsdIxHxwE-ekuN2hjq2I5EUNYkC_u3cQUBLZKOrF6lNOBvVl-FcrWYUY0uCsuQHH74cwXIV-3r9MLh0w-jQLlFfMLdjAxzzA28rAN7pj05d30wsq4jxlCT_xNwjuOMVwXkbC53j9IM0JEiP7Xqfow-yR63RuFrs8i4RGmG4I6iKp6O_fbkifpGWP1F0S10Eps6M-PkMqhZzYY6yuLMsBJD2_H9WB5UAaEVCYfr-6XdYur7g7SKwfYRM8_OvyScjjIjHfWtGiK99lmPnXJKfdPWsZ_uCsxm8_EMiBc6O95uYWvm2T2udInl13iCb3rg4kH1ntufIE_Tk8TTSNXPsbcG2PPSS-M4RzWeD1Ifxitss4ruRVoesoyi_j8pCDHGtQDctSapUfS4YNtOi13aySBDXViMhrdF
VL  - 39
ER  -
TY  - JOUR
AB  - **Background:** 
The central impairments of people with autism spectrum disorder (ASD) affect social interaction and communication. Music therapy uses musical experiences and the relationships that develop through them to enable communication and expression, thus attempting to address some of the core problems of people with ASD. The present version of this review on music therapy for ASD is an update of the original Cochrane review published in 2006.

**Objectives:** 
To assess the effects of music therapy for individuals with ASD.Search methods: We searched the following databases in July 2013: CENTRAL, Ovid MEDLINE, EMBASE, LILACS, PsycINFO, CINAHL, ERIC, ASSIA, Sociological Abstracts, and Dissertation Abstracts International. We also checked the reference lists of relevant studies and contacted investigators in person.

**Selection criteria:** 
All randomised controlled trials (RCTs) or controlled clinical trials comparing music therapy or music therapy added to standard care to &#039;placebo&#039; therapy, no treatment, or standard care for individuals with ASD were considered for inclusion.

**Data collection and analysis:** 
Two authors independently selected studies, assessed risk of bias, and extracted data from all included studies. We calculated the pooled standardised mean difference (SMD) and corresponding 95% confidence interval (CI) for continuous outcomes to allow the combination data from different scales and to facilitate the interpretation of effect sizes. Heterogeneity was assessed using the I&sup2; statistic. In cases of statistical heterogeneity within outcome subgroups, we examined clients&#039; age, intensity of therapy (number and frequency of therapy sessions), and treatment approach as possible sources of heterogeneity.

**Main results:** 
We included 10 studies (165 participants) that examined the short- and medium-term effect of music therapy interventions (one week to seven months) for children with ASD. Music therapy was superior to &#039;placebo&#039; therapy or standard care with respect to the primary outcomes social interaction within the therapy context (SMD 1.06, 95% CI 0.02 to 2.10, 1 RCT, n = 10); generalised social interaction outside of the therapy context (SMD 0.71, 95% CI 0.18 to 1.25, 3 RCTs, n = 57, moderate quality evidence), non-verbal communicative skills within the therapy context (SMD 0.57, 95% CI 0.29 to 0.85, 3 RCTs, n = 30), verbal communicative skills (SMD 0.33, 95% CI 0.16 to 0.49, 6 RCTs, n = 139), initiating behaviour (SMD 0.73, 95% CI 0.36 to 1.11, 3 RCTs, n = 22, moderate quality evidence), and social-emotional reciprocity (SMD 2.28, 95% CI 0.73 to 3.83, 1 RCT, n = 10, low quality evidence). There was no statistically significant difference in non-verbal communicative skills outside of the therapy context (SMD 0.48, 95% CI -0.02 to 0.98, 3 RCTs, n = 57, low quality evidence). Music therapy was also superior to &#039;placebo&#039; therapy or standard care in secondary outcome areas, including social adaptation (SMD 0.41, 95% CI 0.21 to 0.60, 4 RCTs, n = 26), joy (SMD 0.96, 95% CI 0.04 to 1.88, 1 RCT, n = 10), and quality of parent-child relationships (SMD 0.82, 95% CI 0.13 to 1.52, 2 RCTs, n = 33, moderate quality evidence). None of the included studies reported any adverse effects. The small sample sizes of the studies limit the methodological strength of these findings.

**Authors&#039; conclusions:**
The findings of this updated review provide evidence that music therapy may help children with ASD to improve their skills in primary outcome areas that constitute the core of the condition including social interaction, verbal communication, initiating behaviour, and social-emotional reciprocity. Music therapy may also help to enhance non-verbal communication skills within the therapy context. Furthermore, in secondary outcome areas, music therapy may contribute to increasing social adaptation skills in children with ASD and to promoting the quality of parent-child relationships. In contrast to the studies included in an earlier version of this review published in 2006, the new studies included in this update enhanced the applicability of f n ings to clinical practice. More research using larger samples and generalised outcome measures is needed to corroborate these findings and to examine whether the effects of music therapy are enduring. When applying the results of this review to practice, it is important to note that the application of music therapy requires specialised academic and clinical training.
AN  - CD004381
AU  - Geretsegger,
AU  - M.
AU  - Elefant,
AU  - C.
AU  - M&ouml;ssler,
AU  - K.
AU  - A.
AU  - Gold,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD004381.pub3.
KW  - Autistic Disorder [rehabilitation]
KW  - Child Development Disorders, Pervasive [rehabilitation]
KW  - Communication
KW  - Music Therapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Time Factors
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2014
T2  - Cochrane Database of Systematic Reviews
TI  - Music therapy for people with autism spectrum disorder
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004381.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004381.pub3/asset/CD004381.pdf?v=1&amp;t=iw7k96vu&amp;s=7a66638c30726faf2f48c8a97426bda26ac536e2
ER  -
TY  - JOUR
AB  - **Aim:** 
Chronic illness or disability in children can have a deleterious effect on the psychosocial health of well siblings. This systematic review synthesised evidence from studies evaluating sibling-oriented care aimed at improving behavioural and emotional outcomes in well siblings of children with chronic illness or disability. 

** Methods: ** 
Twenty electronic databases were searched. Study selection, data extraction and assessment of methodological quality were performed by two independent reviewers. 

** Results: ** 
Five controlled and nine uncontrolled studies were included. In higher-quality controlled trials, benefits of sibling-oriented care included reduced anxiety, improved mood and behavioural adjustment; however, these findings were not consistently demonstrated across studies. Study differences made it difficult to determine which sibling care features were most salient. 

** Conclusions: ** 
Study findings highlight the potential for enhancing emotional and behavioural outcomes in well siblings. Future evaluations need to clearly identify the intended purpose of the care (what improvements are intended) and which types of siblings are most likely to benefit. This approach may yield more consistent and clinically important results.
AD  - [Hartling, Lisa; Milne, Andrea; Tjosvold, Lisa] Univ Alberta, Dept Pediat, Alberta Res Ctr Hlth Evidence, Fac Med &amp; Dent, Edmonton, AB, Canada. [Newton, Amanda S.] Univ Alberta, Dept Pediat, Fac Med &amp; Dent, Edmonton, AB, Canada. [Wrightson, Dawn] Stollery Childrens Hosp, Edmonton, AB, Canada. [Gallivan, Jennifer] Alberta Hlth Serv, Patients Partners, Div Qual &amp; Serv Improvement, Edmonton, AB, Canada. [Newton, Amanda S.] Women &amp; Childrens Hlth Res Inst, Edmonton, AB, Canada. Newton, AS (reprint author), 8213 Aberhart Ctr One,11402 Univ Ave, Edmonton, AB T6G 2J3, Canada. mandi.newton@ualberta.ca
AN  - WOS:000342799700006
AU  - Hartling,
AU  - L.
AU  - Milne,
AU  - A.
AU  - Tjosvold,
AU  - L.
AU  - Wrightson,
AU  - D.
AU  - Gallivan,
AU  - J.
AU  - Newton,
AU  - A.
AU  - S.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1440-1754.2010.01771.x
J2  - J. Paediatr. Child Health
KW  - health services siblings systematic review HOSPITALIZED CHILDREN ADJUSTMENT CANCER FAMILY PROGRAM IMPACT Pediatrics
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AQ4VX Times Cited: 1 Cited Reference Count: 35 Hartling, Lisa Milne, Andrea Tjosvold, Lisa Wrightson, Dawn Gallivan, Jennifer Newton, Amanda S. Stollery Children&#039;s Hospital Foundation in Edmonton, Alberta The authors would like to acknowledge the important contributions from Ms. Amy Wolgemuth for assisting with initial study screening and Mr Ben Vandermeer for assistance with statistical calculations. Funding for this project was provided by the Stollery Children&#039;s Hospital Foundation in Edmonton, Alberta. Dr Newton is a training Fellow (Career Development Award) in the Canadian Child Health Clinician Scientist Program, in partnership with SickKids Foundation, Child &amp; Family Research Institute (British Columbia), Women &amp; Children&#039;s Health Research Institute (Alberta), Manitoba Institute of Child Health. 1 WILEY-BLACKWELL HOBOKEN J PAEDIATR CHILD H
PY  - 2014
SP  - E26-E38
T2  - Journal of Paediatrics and Child Health
TI  - A systematic review of interventions to support siblings of children with chronic illness or disability
UR  - &lt;Go to ISI&gt;://WOS:000342799700006http://onlinelibrary.wiley.com/store/10.1111/j.1440-1754.2010.01771.x/asset/jpc1771.pdf?v=1&amp;t=ib3ifufb&amp;s=b101c1ec6ed345e91aa79d4973c098d67d8f1954
VL  - 50
ER  -
TY  - JOUR
AB  - The widespread availability of the Internet and mobile-device applications (apps) is changing the treatment of mental health problems. The aim of the present study was to review the research on the effectiveness of e-therapy for eating disorders, using the methodology employed by the UK&#039;s National Institute for Health and Care Excellence (NICE). 

Electronic databases were searched for published randomised controlled trials of e-therapies, designed to prevent or treat any eating disorder in all age groups. Studies were meta-analysed where possible, and effect sizes with confidence intervals were calculated. The GRADE approach was used to determine the confidence in the effect estimates. 

Twenty trials met the inclusion criteria. For prevention, a CBT-based e-intervention was associated with small reductions in eating disorder psychopathology, weight concern and drive for thinness, with moderate confidence in the effect estimates. 

For treatment and relapse prevention, various e-therapies showed some beneficial effects, but for most outcomes, evidence came from single studies and confidence in the effect estimates was low. 

Overall, although some positive findings were identified, the value of e-therapy for eating disorders must be viewed as uncertain. Further research, with improved methods, is needed to establish the effectiveness of e-therapy for people with eating disorders.
AN  - 25461787
AU  - Loucas,
AU  - C.
AU  - E.
AU  - Fairburn,
AU  - C.
AU  - G.
AU  - Whittington,
AU  - C.
AU  - Pennant,
AU  - M.
AU  - E.
AU  - Stockton,
AU  - S.
AU  - Kendall,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.brat.2014.09.011
L1  - internal-pdf://0648127239/Loucas-2014-E-therapy in the treatment and pre.pdf
PY  - 2014
SP  - 122-31
T2  - Behaviour Research &amp; Therapy
TI  - E-therapy in the treatment and prevention of eating disorders: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25461787
UR  - https://www.sciencedirect.com/science/article/pii/S0005796714001624?via%3Dihub
VL  - 63
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Precise estimated risks and benefits of quetiapine for acute bipolar depression are needed for clinical practice. 

**OBJECTIVE: **
To systematically review the efficacy and the tolerability of quetiapine, either as monotherapy or combination therapy, for acute bipolar depression. 

**METHODS: **
We included all randomized, controlled trials (RCTs) comparing quetiapine with other treatments, including placebo, in patients with acute bipolar depression (bipolar I or II disorder, major depressive episode). Published and unpublished RCTs were identified using the Cochrane Central Register of Controlled Trials, MEDLINE, Web of Knowledge, CINAHL, PsycINFO, the EU Clinical Trials Register database, and ClinicalTrials.gov. The primary outcome was the change scores of depression rating scales. 

**RESULTS: **
Eleven RCTs (n=3,488) were included. Two of them were conducted in children and adolescents. The change in depression scores was significantly greater in the quetiapine group compared with the placebo group (mean difference, [MD] =-4.66, 95% confidence interval [CI] -5.59 to -3.73). The significant difference was observed from week 1. Compared with placebo, quetiapine had higher incidence rates of extrapyramidal side effects, sedation, somnolence, dizziness, fatigue, constipation, dry mouth, increased appetite, and weight gain but lower risks of treatment-emergent mania and headache. Quetiapine treatment was associated with significant improvement of clinical global impression, quality of life, sleep quality, anxiety, and functioning. 

**CONCLUSION: **
Quetiapine monotherapy is effective for acute bipolar depression and the prevention of mania/hypomania switching. Its common adverse effects are extrapyramidal side effects, sedation, somnolence, dizziness, fatigue, constipation, dry mouth, increased appetite, and weight gain. The lower risk of headache in quetiapine-treated patients with acute bipolar depression should be further investigated. The evidence for the use of quetiapine combined with mood stabilizers in children and adolescents with acute bipolar depression is too small to support the clinical practice.
AD  - Suttajit,Sirijit. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Srisurapanont,Manit. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Maneeton,Narong. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Maneeton,Benchalak. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
AN  - 25028535
AU  - Suttajit,
AU  - S.
AU  - Srisurapanont,
AU  - M.
AU  - Maneeton,
AU  - N.
AU  - Maneeton,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2147/DDDT.S63779
DP  - Ovid Technologies
J2  - Drug Des Devel Ther
LA  - English
N1  - Suttajit, Sirijit Srisurapanont, Manit Maneeton, Narong Maneeton, Benchalak
PY  - 2014
SP  - 827-38
T2  - Drug design, development &amp; therapy
TI  - Quetiapine for acute bipolar depression: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25028535 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25028535&amp;id=doi:10.2147%2FDDDT.S63779&amp;issn=1177-8881&amp;isbn=&amp;volume=8&amp;issue=&amp;spage=827&amp;pages=827-38&amp;date=2014&amp;title=Drug+design%2C+development+%26+therapy&amp;atitle=Quetiapine+for+acute+bipolar+depression%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Suttajit&amp;pid=%3Cauthor%3ESuttajit+S%3C%2Fauthor%3E%3CAN%3E25028535%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.dovepress.com/getfile.php?fileID=20590
VL  - 8
ER  -
TY  - JOUR
AB  - **Background: **
Psychostimulant medication, most commonly the catecholamine agonist methylphenidate, is the most effective treatment for attention-deficit/hyperactivity disorder (ADHD). However, relatively little is known on the mechanisms of action. Acute effects on brain function can elucidate underlying neurocognitive effects. We tested methylphenidate effects relative to placebo in functional magnetic resonance imaging (fMRI) during three disorder-relevant tasks in medication-naive ADHD adolescents. In addition, we conducted a systematic review and meta-analysis of the fMRI findings of acute stimulant effects on ADHD brain function. 

**Methods:** 
The fMRI study compared 20 adolescents with ADHD under either placebo or methylphenidate in a randomized controlled trial while performing stop, working memory, and time discrimination tasks. The meta-analysis was conducted searching PubMed, ScienceDirect, Web of Knowledge, Google Scholar, and Scopus databases. Peak coordinates of clusters of significant effects of stimulant medication relative to placebo or off medication were extracted for each study. 

**Results: **
The fMRI analysis showed that methylphenidate significantly enhanced activation in bilateral inferior frontal cortex (IFC)/insula during inhibition and time discrimination but had no effect on working memory networks. The meta-analysis, including 14 fMRI datasets and 212 children with ADHD, showed that stimulants most consistently enhanced right IFC/insula activation, which also remained for a subgroup analysis of methylphenidate effects alone. A more lenient threshold also revealed increased putamen activation. 

**Conclusions: **
Psychostimulants most consistently increase right IFC/insula activation, which are key areas of cognitive control and also the most replicated neurocognitive dysfunction in ADHD. These neurocognitive effects may underlie their positive clinical effects.
AD  - [Rubia, Katya; Alegria, Analucia A.; Cubillo, Ana I.; Smith, Anna B.] Kings Coll London, Inst Psychiat, Dept Child &amp; Adolescent Psychiat, London SE5 8AF, England. [Brammer, Michael J.] Kings Coll London, Inst Psychiat, Dept Neuroimaging, London SE5 8AF, England. [Radua, Joaquim] Germanes Hosp, Fundacio Invest &amp; Docencia Maria Angustias Gimene, Barcelona, Spain. [Radua, Joaquim] Ctr Invest Biomed Red Salud Mental, Barcelona, Spain. Rubia, K (reprint author), Kings Coll London, SGDP, Inst Psychiat, Dept Child &amp; Adolescent Psychiat, Po46,16 Crespigny Pk, London SE5 8AF, England. katya.rubia@kcl.ac.uk
AN  - WOS:000343094400007
AU  - Rubia,
AU  - K.
AU  - Alegria,
AU  - A.
AU  - A.
AU  - Cubillo,
AU  - A.
AU  - I.
AU  - Smith,
AU  - A.
AU  - B.
AU  - Brammer,
AU  - M.
AU  - J.
AU  - Radua,
AU  - J.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.biopsych.2013.10.016
J2  - Biol. Psychiatry
KW  - ADHD fMRI meta-analysis methylphenidate review stimulants DEFICIT HYPERACTIVITY DISORDER OBSESSIVE-COMPULSIVE DISORDER MEDICATION-NAIVE ADOLESCENTS INFERIOR FRONTAL GYRUS MAGNETIC-RESONANCE PREFRONTAL CORTEX COGNITIVE CONTROL INTERFERENCE INHIBITION TIM
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AQ8QL Times Cited: 3 Cited Reference Count: 91 Rubia, Katya Alegria, Analucia A. Cubillo, Ana I. Smith, Anna B. Brammer, Michael J. Radua, Joaquim National Institute of Health Research Biomedical Research Centre for Mental Health at South London; Maudsley National Health Service Foundation Trust; Institute of Psychiatry, Kings College London; Lilly Pharmaceuticals; National Institute of Health Research Biomedical Research Centre; Institute of Psychiatry Ph.D. Excellence award This work was supported by grants by the National Institute of Health Research Biomedical Research Centre for Mental Health at South London and Maudsley National Health Service Foundation Trust and Institute of Psychiatry, Kings College London, and Lilly Pharmaceuticals. Dr. Anna Smith, Dr. Ana Cubillo, and Dr. Andrew Simmons are supported by the National Institute of Health Research Biomedical Research Centre. Ms. Alzamora was supported by an Institute of Psychiatry Ph.D. Excellence award. Lilly Pharmaceuticals had no input into the design, analysis, data interpretation, or write-up. 3 ELSEVIER SCIENCE INC NEW YORK BIOL PSYCHIAT
PY  - 2014
SP  - 616-628
T2  - Biological Psychiatry
TI  - Effects of Stimulants on Brain Function in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000343094400007http://ac.els-cdn.com/S0006322313009529/1-s2.0-S0006322313009529-main.pdf?_tid=3cad900c-18b6-11e5-a890-00000aacb35f&amp;acdnat=1434960848_0b22bab16a3b8933be4c6ff13cf12e6d
VL  - 76
ER  -
TY  - JOUR
AB  - Neighbourhood risk factors have been shown to be associated with youth violence and predictors of youth violence. 

This systematic review examined the existing evidence for youth violence interventions involving the deconcentration of poverty and urban upgrading. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Cassidy, Tali: talicassidy@gmail.com Cassidy, Tali, talicassidy@gmail.com Cassidy, Tali: School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa Inglis, Gabrielle: Gender Health and Justice Research Unit, University of Cape Town, Cape Town, South Africa Wiysonge, Charles: Centre for Evidence-based Health Care, Department of Interdisciplinary Health Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Stellenbosch, South Africa Matzopoulos, Richard: School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
AN  - 2014-06504-012
AU  - Cassidy,
AU  - T.
AU  - Inglis,
AU  - G.
AU  - Wiysonge,
AU  - C.
AU  - Matzopoulos,
AU  - R.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.healthplace.2013.12.009
DP  - Ovid Technologies
KW  - housing vouchers, poverty deconcentration, urban upgrading, youth violence, risk factors *Community Development *Poverty *Risk Factors Housing Violence Social Structure &amp; Organization [2910] Human
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2014
SP  - 78-87
T2  - Health &amp; Place
TI  - A systematic review of the effects of poverty deconcentration and urban upgrading on youth violence
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2014-06504-012 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.healthplace.2013.12.009&amp;issn=1353-8292&amp;isbn=&amp;volume=26&amp;issue=&amp;spage=78&amp;pages=78-87&amp;date=2014&amp;title=Health+%26+Place&amp;atitle=A+systematic+review+of+the+effects+of+poverty+deconcentration+and+urban+upgrading+on+youth+violence.&amp;aulast=Cassidy&amp;pid=%3Cauthor%3ECassidy%2C+Tali%3C%2Fauthor%3E%3CAN%3E2014-06504-012%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1353829213001731/1-s2.0-S1353829213001731-main.pdf?_tid=c0678c96-18dd-11e5-9dee-00000aab0f27&amp;acdnat=1434977820_691c0130b98b6a0e43eb651c94952c0b
VL  - 26
ER  -
TY  - JOUR
AB  - Objective: 
To examine the effects of school-based interventions on the well-being of military-connected children (i.e., dependents of U.S. military service members, veterans, or reserve component members) who attend public or private elementary or secondary schools with parental deployment, parental reintegration, parental military-related trauma or death, or frequent moves. 

Method: 
Systematic review methods were employed to search, retrieve, select, and analyze studies that met inclusion criteria. Results: Over 1,400 citations were reviewed and 22 full-text reports were screened. One study met criteria for inclusion in this review. Effects on anxiety, self-esteem, and internalizing and externalizing behaviors were not significant. 

Discussion: 
The paucity of intervention research in this area is surprising, given the increased awareness and research on the stresses and impacts of military deployment and other unique stressors related to military life on children. The results of this systematic review support the need for further development and testing of school-based interventions that address the needs of military-connected children.
AD  - [Brendel, Kristen Esposito; Bellomo, Mary] Aurora Univ, Sch Social Work, Aurora, IL 60506 USA. [Maynard, Brandy R.] St Louis Univ, Sch Social Work, St Louis, MO 63103 USA. [Albright, David L.] Univ Missouri, Sch Social Work, Columbia, MO USA. Brendel, KE (reprint author), Aurora Univ, Sch Social Work, 347 Gladstone, Aurora, IL 60506 USA. kbrendel@aurora.edu
AN  - WOS:000343770200001
AU  - Brendel,
AU  - K.
AU  - E.
AU  - Maynard,
AU  - B.
AU  - R.
AU  - Albright,
AU  - D.
AU  - L.
AU  - Bellomo,
AU  - M.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1049731513517143
J2  - Res. Soc. Work. Pract.
KW  - systematic review military children school-based interventions PARENTAL DEPLOYMENT SERVICE MEMBERS FAMILIES IMPACT YOUTH Social Work
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AR7OX Times Cited: 0 Cited Reference Count: 54 Brendel, Kristen Esposito Maynard, Brandy R. Albright, David L. Bellomo, Mary SAGE PUBLICATIONS INC THOUSAND OAKS RES SOCIAL WORK PRAC
PY  - 2014
SP  - 649-658
T2  - Research on Social Work Practice
TI  - Effects of School-Based Interventions With US Military-Connected Children: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000343770200001http://rsw.sagepub.com/content/24/6/649http://rsw.sagepub.com/content/24/6/649.full.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - Mindfulness meditation is a well-validated intervention for symptoms of depression and anxiety disorders in adults, with meta-analyses showing moderate effect sizes. 

This study marks the first published meta-analysis of the burgeoning literature on mindfulness meditation with youth (conducted between 2004 and 2011) and identifies specific outcomes and sub-populations for whom mindfulness may be particularly helpful. Inclusion criteria were peer-reviewed journal articles published in English, study participants under 18 years of age, and a description in the methods section of mindfulness as the chief component of an intervention. 

A systematic search was conducted, of which upon review, 20 articles met inclusion criteria. Mindfulness interventions with youth overall were found to be helpful and not to carry iatrogenic harm, with the primary omnibus effect size (del) in the small to moderate range (0.23, p&lt;.0001), indicating the superiority of mindfulness treatments over active control comparison conditions. 

A significantly larger effect size was found on psychological symptoms compared to other dependent variable types (0.37 vs. 0.21, p=.028), and for studies drawn from clinical samples compared to non-clinical sample (0.50 vs. 0.20, p=.024). 

Mindfulness appears to be a promising intervention modality for youth. Although to date the majority of studies on mindfulness with youth engage generally healthy participants recruited from schools, the findings of this meta-analysis suggest that future research might focus on youth in clinical settings and target symptoms of psychopathology. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Zoogman, Sarah: sz78@columba.edu
AN  - 2014-01649-001
AU  - Zoogman,
AU  - S.
AU  - Goldberg,
AU  - S.
AU  - B.
AU  - Hoyt,
AU  - W.
AU  - T.
AU  - Miller,
AU  - L.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s12671-013-0260-4
DP  - Ovid Technologies
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
PY  - 2014
SP  - No Pagination Specified
T2  - Mindfulness
TI  - Mindfulness interventions with youth: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2014-01649-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs12671-013-0260-4&amp;issn=1868-8527&amp;isbn=&amp;volume=&amp;issue=&amp;spage=No&amp;pages=No+Pagination+Specified&amp;date=2014&amp;title=Mindfulness&amp;atitle=Mindfulness+interventions+with+youth%3A+A+meta-analysis.&amp;aulast=Zoogman&amp;pid=%3Cauthor%3EZoogman%2C+Sarah%3C%2Fauthor%3E%3CAN%3E2014-01649-001%3C%2FAN%3E%3CDT%3E%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs12671-013-0260-4http://download.springer.com/static/pdf/760/art%253A10.1007%252Fs12671-013-0260-4.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs12671-013-0260-4&amp;token2=exp=1435231758~acl=%2Fstatic%2Fpdf%2F760%2Fart%25253A10.1007%25252Fs12671-013-0260-4.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs12671-013-0260-4*~hmac=a82ee0e2bbded886a625ee745f8727c14c905e07c1a9875f3e94981c1584633c
ER  -
TY  - JOUR
AB  - Among clinicians, it is common practice to include parents in treatment, and it has been taken for granted that parents&#039; involvement in their children&#039;s treatment is beneficial for therapy outcome, although research on this issue is far from clear. 

A meta-analysis was carried out in order to investigate whether parent involvement potentiates the outcome for children with anxiety disorders when treated with cognitive-behavior therapy. 

Sixteen studies, which directly compared parent-involved treatments with child-only treatments, were included in the meta-analysis. 

The results showed a small, nonsignificant effect size of - 0.10 in favor of the child-only treatments. There was no indication of publication bias in the analysis. Implications of the results are discussed.
AD  - Thulin,Ulrika. a Department of Clinical Neuroscience , Centre for Psychiatric Research and Education, Karolinska Institutet , Stockholm , Sweden.
AN  - 24950054
AU  - Thulin,
AU  - U.
AU  - Svirsky,
AU  - L.
AU  - Serlachius,
AU  - E.
AU  - Andersson,
AU  - G.
AU  - Ost,
AU  - L.
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/16506073.2014.923928
DP  - Ovid Technologies
J2  - Cognitive Behav Ther
KW  - Adult Anxiety Disorders/px [Psychology] *Anxiety Disorders/th [Therapy] Child *Cognitive Therapy/mt [Methods] *Family Therapy/mt [Methods] Humans *Parent-Child Relations *Parents Treatment Outcome
L1  - internal-pdf://3314078510/Thulin-2014-The effect of parent involvement i.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Thulin, Ulrika Svirsky, Liv Serlachius, Eva Andersson, Gerhard Ost, Lars-Goran
PY  - 2014
SP  - 185-200
T2  - Cognitive Behaviour Therapy
TI  - The effect of parent involvement in the treatment of anxiety disorders in children: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24950054 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24950054&amp;id=doi:10.1080%2F16506073.2014.923928&amp;issn=1650-6073&amp;isbn=&amp;volume=43&amp;issue=3&amp;spage=185&amp;pages=185-200&amp;date=2014&amp;title=Cognitive+Behaviour+Therapy&amp;atitle=The+effect+of+parent+involvement+in+the+treatment+of+anxiety+disorders+in+children%3A+a+meta-analysis.&amp;aulast=Thulin&amp;pid=%3Cauthor%3EThulin+U%3C%2Fauthor%3E%3CAN%3E24950054%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/16506073.2014.923928
UR  - http://www.tandfonline.com/doi/pdf/10.1080/16506073.2014.923928?needAccess=true
VL  - 43
ER  -
TY  - JOUR
AB  - This review presents a novel framework for evaluating evidence based on a set of parallel criteria that can be applied to both group and single-subject experimental design (SSED) studies. 

The authors illustrate use of this evaluation system in a systematic review of 67 articles investigating social skills interventions for preschoolers with autism spectrum disorder. 

Results characterize the types of treatments and research designs, the quality of studies, and effect sizes. 

In contrast to prior reports, this review revealed strong evidence of treatment efficacy, with group designs receiving lower ratings than SSED studies. 

Because this framework provides a comprehensive and transparent approach to judging the quality of studies individually and collectively, it holds promise for improving methods for identibing and implementing evidence-based practices.
AD  - [Goldstein, Howard] Univ S Florida, Tampa, FL 33612 USA. [Lackey, Kimberly C.] Western Carolina Univ, Cullowhee, NC 28723 USA. [Schneider, Naomi J. B.] Ohio State Univ, Dept Human Sci, Columbus, OH 43210 USA. Goldstein, H (reprint author), Univ S Florida, Coll Behav &amp; Community Sci, 13301 Bruce B Downs Blvd,MHC 1110, Tampa, FL 33612 USA. hgoldstein@usf.edu
AN  - WOS:000333503500002
AU  - Goldstein,
AU  - H.
AU  - Lackey,
AU  - K.
AU  - C.
AU  - Schneider,
AU  - N.
AU  - J.
AU  - B.
DA  - Spr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0014402914522423
J2  - Except. Child.
KW  - SINGLE-CASE RESEARCH YOUNG-CHILDREN SPECTRUM DISORDERS DEVELOPMENTAL-DISABILITIES SOCIODRAMATIC PLAY SPECIAL-EDUCATION EFFECT SIZE PEERS BEHAVIOR COMMUNICATION Education, Special Rehabilitation
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AD8GC Times Cited: 1 Cited Reference Count: 85 Goldstein, Howard Lackey, Kimberly C. Schneider, Naomi J. B. Goldstein, Howard/P-3161-2014 Goldstein, Howard/0000-0003-3270-2739 1 SAGE PUBLICATIONS INC THOUSAND OAKS EXCEPT CHILDREN
PY  - 2014
SP  - 262-286
T2  - Exceptional Children
TI  - A New Framework for Systematic Reviews: Application to Social Skills Interventions for Preschoolers With Autism
UR  - &lt;Go to ISI&gt;://WOS:000333503500002http://ecx.sagepub.com/content/80/3/262http://ecx.sagepub.com/content/80/3/262.full.pdf
VL  - 80
ER  -
TY  - JOUR
AB  - Multisystemic Therapy (MST) is a well-established intervention for juvenile delinquents and/or adolescents showing social, emotional and behavioral problems. A multilevel meta-analysis of k = 22 studies, containing 332 effect sizes, consisting of N = 4066 juveniles, was conducted to examine the effectiveness of MST. 

Small but significant treatment effects were found on delinquency (primary outcome) and psychopathology, substance use, family factors, out-of-home placement and peer factors, whereas no significant treatment effect was found for skills and cognitions. 

Moderator analyses showed that study characteristics (country where the research was conducted, efficacy versus effectiveness, and study quality), treatment characteristics (single versus multiple control treatments and duration of MST treatment), sample characteristics (target population, age, gender and ethnicity) and outcome characteristics (non-specific versus violent/non-violent offending, correction for pretreatment differences, and informant type) moderated the effectiveness of MST. 

MST seems most effective with juveniles under the age of 15, with severe starting conditions. Furthermore, the effectiveness of MST may be improved when treatment for older juveniles is focused more on peer relationships and risks and protective factors in the school domain. 

Copyright &copy; 2013 Elsevier Ltd.
AD  - (van der Stouwe, Asscher, Stams) Forensic Child and Youth Care Sciences, University of Amsterdam, Amsterdam, Netherlands (Dekovic) Clinical Child and Family Sciences, Utrecht University, Netherlands (van der Laan) Criminology, VU University, Amsterdam, Netherlands (van der Laan) Netherlands Institute for the Study of Crime and Law Enforcement, Amsterdam, Netherlands T. van der Stouwe, Forensic Child and Youth Care Sciences, University of Amsterdam, Nieuwe Achtergracht 127, Amsterdam 1018 WS, Netherlands. E-mail: t.vanderstouwe@uva.nl
AN  - 605203802
AU  - van
AU  - der
AU  - Stouwe,
AU  - T.
AU  - Asscher,
AU  - J.
AU  - J.
AU  - Stams,
AU  - G.
AU  - J.
AU  - J.
AU  - M.
AU  - Dekovic,
AU  - M.
AU  - van
AU  - der
AU  - Laan,
AU  - P.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
KW  - Effectiveness
KW  - Juvenile delinquency
KW  - mst
KW  - Multilevel meta-analysis
KW  - Multisystemic Therapy
KW  - behavior therapy
KW  - cognition
KW  - ethnicity
KW  - family functioning
KW  - human
KW  - mental disease
KW  - meta analysis
KW  - peer group
KW  - review
KW  - self report
KW  - sexual crime
KW  - skill
KW  - social problem
KW  - substance use
KW  - therapy effect
KW  - adolescent
KW  - delinquency
KW  - effect size
KW  - gender
KW  - juvenile
KW  - population
KW  - protection
KW  - risk
KW  - school
KW  - therapy
L1  - internal-pdf://0171957624/van der-2014-The effectiveness of Multisystemi.pdf
LA  - English
M3  - Review
PY  - 2014
SP  - 468-481
T2  - Clinical Psychology Review
TI  - The effectiveness of Multisystemic Therapy (MST): A meta-analysis
UR  - http://www.elsevier.com/locate/clinpsychrevhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18a&amp;AN=605203802http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.cpr.2014.06.006&amp;issn=0272-7358&amp;isbn=&amp;volume=34&amp;issue=6&amp;spage=468&amp;pages=468-481&amp;date=2014&amp;title=Clinical+Psychology+Review&amp;atitle=The+effectiveness+of+Multisystemic+Therapy+%28MST%29%3A+A+meta-analysis&amp;aulast=van+der+Stouwe&amp;pid=%3Cauthor%3Evan+der+Stouwe+T.%3C%2Fauthor%3E%3CAN%3E605203802%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0272735814000981/1-s2.0-S0272735814000981-main.pdf?_tid=3fdaa2fc-04d1-11e7-87b5-00000aacb35e&amp;acdnat=1489068422_b3560fa15e2b17ed807327cb7e8ccf35
VL  - 34
ER  -
TY  - JOUR
AB  - **Background: **
Attention Bias Modification (ABM) is a novel computer based treatment for anxiety disorders. It has been proposed as an efficient, accessible psychological therapy and is based on cognitive theories of attention. The present review sought to investigate the efficacy of ABM as a potential treatment for child and adolescent anxiety. 

**Method: **
A systematic literature review was conducted, using three main databases, PsycINFO, Embase and Medline, to identify original research articles which measured the effect of ABM on anxiety levels in children and/or adolescents. 

**Results: **
Ten articles met the inclusion criteria and of these 10, three were randomised control trials. A lack of standardisation in relation to the treatment protocol was observed; nonetheless the identified studies generally provided evidence for the efficacy of ABM as an anxiety treatment. 

**Limitations: **
Due to the nature of the studies found, a statistical meta-analysis was not possible. 

**Conclusions: **
ABM seems to be a promising, novel treatment for child and/or adolescent anxiety disorders with merits over lengthier, talking based therapies. However, more rigorous research trials are needed to clarify the mechanisms behind ABM and establish effective, standardised treatment protocols. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Lowther, Helen: s1163723@sms.ed.ac.uk Lowther, Helen: Andrew Lang Unit, Viewfield Lane, Scottish Borders, Selkirk, Scotland, TD74LJ, s1163723@sms.ed.ac.uk Lowther, Helen: Child and Adolescent Mental Health Team, Selkirk, United Kingdom Newman, Emily: Clinical and Health Psychology, School of Health in Social Science, University of Edinburgh, Edinburgh, United Kingdom
AN  - 2014-40023-020
AU  - Lowther,
AU  - H.
AU  - Newman,
AU  - E.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
KW  - Attention bias modification, Anxiety, Children, Adolescents, Review
KW  - *Anxiety Disorders
KW  - *Pediatrics
KW  - *Computer Assisted Therapy
KW  - *Attentional Bias
KW  - Anxiety
KW  - Specialized Interventions [3350]
KW  - Adolescent
KW  - Anxiety Disorders
KW  - Attention
KW  - Behavior Therapy
KW  - Child
KW  - Female
KW  - Humans
KW  - Male
KW  - Therapy, Computer-Assisted
KW  - Treatment Outcome
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://0266687711/Lowther-2014-Attention bias modification (ABM).pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2014
SP  - 125-135
T2  - Journal of Affective Disorders
TI  - Attention bias modification (ABM) as a treatment for child and adolescent anxiety: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2014-40023-020http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jad.2014.06.051&amp;issn=0165-0327&amp;isbn=&amp;volume=168&amp;issue=&amp;spage=125&amp;pages=125-135&amp;date=2014&amp;title=Journal+of+Affective+Disorders&amp;atitle=Attention+bias+modification+%28ABM%29+as+a+treatment+for+child+and+adolescent+anxiety%3A+A+systematic+review.&amp;aulast=Lowther&amp;pid=%3Cauthor%3ELowther%2C+Helen%3C%2Fauthor%3E%3CAN%3E2014-40023-020%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://ac.els-cdn.com/S0165032714004194/1-s2.0-S0165032714004194-main.pdf?_tid=724e8254-04cb-11e7-9a03-00000aacb35e&amp;acdnat=1489065930_90bb4dc093811d5376ffecd3562a5f31
VL  - 168
ER  -
TY  - JOUR
AB  - The aim of this paper is to present a meta-analysis about the differential efficacy of cognitive-behavioral therapy (CBT), pharmacological and combined treatment for pediatric obsessive-compulsive disorder (OCD). The literature research and the application of the inclusion criteria enabled us to locate 18 studies, yielding a total of 24 independent comparisons between a treated (10 pharmacological, 11 CBT, and 3 combined interventions) and a control group. All types of interventions were efficacious in reducing obsessive-compulsive symptoms, with effect sizes adjusted by the type of control group of d=1.203 for CBT, d=0.745 for pharmacological treatments, and d=1.704 for mixed treatments. Depression, anxiety and other secondary responses were also improved, especially with CBT interventions. The analysis of moderator variables showed that the CBT protocol and the total of intervention hours exhibited a significant influence on the effect size. Within pharmacological treatment, clomipramine (d=1.305) was more efficacious than selective serotonin reuptake inhibitors (d=0.644), but its adverse effects were more severe. Finally, the clinical implications of the results are discussed. Copyright &copy; 2013 Elsevier Ltd. All rights reserved.
AD  - Sanchez-Meca,Julio. Faculty of Psychology, Espinardo Campus, University of Murcia, 30100 Murcia, Spain. Electronic address: jsmeca@um.es. Rosa-Alcazar,Ana I. Faculty of Psychology, Espinardo Campus, University of Murcia, 30100 Murcia, Spain. Electronic address: airosa@um.es. Iniesta-Sepulveda,Marina. Faculty of Health Sciences, Campus de Los Jeronimos, Catholic University of Murcia, 30107 Murcia, Spain. Electronic address: miniesta@ucam.edu. Rosa-Alcazar,Angel. Faculty of Psychology, Espinardo Campus, University of Murcia, 30100 Murcia, Spain. Electronic address: arosaymj@hotmail.com.
AN  - 24334214
AU  - Sanchez-Meca,
AU  - J.
AU  - Rosa-Alcazar,
AU  - A.
AU  - I.
AU  - Iniesta-Sepulveda,
AU  - M.
AU  - Rosa-Alcazar,
AU  - A.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.janxdis.2013.10.007
DP  - Ovid Technologies
J2  - J Anxiety Disord
KW  - Child *Cognitive Therapy Combined Modality Therapy Humans Obsessive-Compulsive Disorder/dt [Drug Therapy] *Obsessive-Compulsive Disorder/th [Therapy] Randomized Controlled Trials as Topic Serotonin Uptake Inhibitors/ae [Adverse Effects] Serotonin Uptake
LA  - English
M3  - Meta-Analysis Review
N1  - Sanchez-Meca, Julio Rosa-Alcazar, Ana I Iniesta-Sepulveda, Marina Rosa-Alcazar, Angel S0887-6185(13)00208-9
PY  - 2014
SP  - 31-44
T2  - Journal of Anxiety Disorders
TI  - Differential efficacy of cognitive-behavioral therapy and pharmacological treatments for pediatric obsessive-compulsive disorder: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24334214
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24334214&amp;id=doi:10.1016%2Fj.janxdis.2013.10.007&amp;issn=0887-6185&amp;isbn=&amp;volume=28&amp;issue=1&amp;spage=31&amp;pages=31-44&amp;date=2014&amp;title=Journal+of+Anxiety+Disorders&amp;atitle=Differential+efficacy+of+cognitive-behavioral+therapy+and+pharmacological+treatments+for+pediatric+obsessive-compulsive+disorder%3A+a+meta-analysis.&amp;aulast=Sanchez-Meca&amp;pid=%3Cauthor%3ESanchez-Meca+J%3C%2Fauthor%3E%3CAN%3E24334214%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0887618513002089/1-s2.0-S0887618513002089-main.pdf?_tid=cad77c16-165a-11e5-a6b9-00000aacb35e&amp;acdnat=1434701671_dfe0b66586829bbaedb54c701c8a335e
VL  - 28
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To evaluate the comparative benefits and harms in both mother and child of antidepressant treatment for depression in pregnant or postpartum women. 

**DATA SOURCES: **
MEDLINE, the Cochrane Library, CINAHL, Scopus, ClinicalTrials.gov (inception to July 2013), manufacturers, and reference lists. 

**METHODS OF STUDY SELECTION: **
Two reviewers independently selected studies of pregnant women with depression comparing antidepressants with each other, placebo or no treatment, or nondrug treatments. Studies making comparisons among women taking antidepressants for any reason and those not taking antidepressants (depression status unknown) were used to fill gaps in the evidence. 

**TABULATION, INTEGRATION, AND RESULTS: **
Dual study data extraction and quality assessment were used. Six randomized controlled trials and 15 observational studies provided evidence. Low-strength evidence suggested neonates of pregnant women with depression taking selective serotonin reuptake inhibitors had higher risk of respiratory distress than did neonates of untreated women (13.9% compared with 7.8%; P&lt;.001) but no difference in risk of neonatal convulsions (0.14% compared with 0.11%; P=.64) or preterm birth (17% compared with 10%; P=.07). Indirect evidence from studies of pregnant women receiving antidepressants for mixed or unreported reasons compared with pregnant women not taking antidepressants (depression status unknown) suggested future research should focus on congenital anomalies and autism spectrum and attention deficit disorders in the child. In postpartum depression, low-strength evidence suggested symptom response was not improved when sertraline was added to psychotherapy or when cognitive-behavioral therapy was added to paroxetine. Evidence was insufficient for other outcomes, including depression symptoms, functional capacity, breastfeeding, and infant and child development. A serious limitation is the lack of study populations of exclusively depressed pregnant and postpartum women. 

**CONCLUSION: **
Evidence about the comparative benefits and harms of pharmacologic treatment of depression in pregnant and postpartum women was largely inadequate to allow informed decisions about treatment. Considering the prevalence of depression, filling this gap is essential.
AD  - McDonagh,Marian S. Departments of Medical Informatics and Clinical Epidemiology, Psychiatry, Pediatrics, and Obstetrics and Gynecology, Oregon Health and Science University, School of Medicine, and Portland Veterans Affairs Hospital, Portland, Oregon.
AN  - 25004304
AU  - McDonagh,
AU  - M.
AU  - S.
AU  - Matthews,
AU  - A.
AU  - Phillipi,
AU  - C.
AU  - Romm,
AU  - J.
AU  - Peterson,
AU  - K.
AU  - Thakurta,
AU  - S.
AU  - Guise,
AU  - J.
AU  - M.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/AOG.0000000000000410
DP  - Ovid Technologies
J2  - Obstet Gynecol
KW  - Antidepressive Agents/ad [Administration &amp; Dosage] *Antidepressive Agents/ae [Adverse Effects] Antidepressive Agents/cl [Classification] Breast Feeding/ae [Adverse Effects] Comparative Effectiveness Research *Depression, Postpartum/dt [Drug Therapy] *De
L1  - internal-pdf://2026900294/McDonagh-2014-Depression drug treatment outcom.pdf
LA  - English
M3  - Research Support, U.S. Gov&#039;t, P.H.S. Review
N1  - McDonagh, Marian S Matthews, Annette Phillipi, Carrie Romm, Jillian Peterson, Kim Thakurta, Sujata Guise, Jeanne-Marie HHSA 290200710057I (United States PHS HHS)
PY  - 2014
SP  - 526-34
T2  - Obstetrics and Gynecology
TI  - Depression drug treatment outcomes in pregnancy and the postpartum period: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25004304 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25004304&amp;id=doi:10.1097%2FAOG.0000000000000410&amp;issn=0029-7844&amp;isbn=&amp;volume=124&amp;issue=3&amp;spage=526&amp;pages=526-34&amp;date=2014&amp;title=Obstetrics+%26+Gynecology&amp;atitle=Depression+drug+treatment+outcomes+in+pregnancy+and+the+postpartum+period%3A+a+systematic+review+and+meta-analysis.&amp;aulast=McDonagh&amp;pid=%3Cauthor%3EMcDonagh+MS%3C%2Fauthor%3E%3CAN%3E25004304%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://graphics.tx.ovid.com/ovftpdfs/FPDDNCOBHEDDGG00/fs047/ovft/live/gv024/00006250/00006250-201409000-00008.pdf
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCDCDBALNL00/fs047/ovft/live/gv024/00006250/00006250-201409000-00008.pdf
VL  - 124
ER  -
TY  - JOUR
AB  - This study systematically examined the efficacy and safety of psychopharmacological and non-psychopharmacological treatments for anxiety in youth with autism spectrum disorders (ASD). 

Four psychopharmacological, nine cognitive behavioral therapy (CBT), and two alternative treatment studies met inclusion criteria. 

Psychopharmacological studies were descriptive or open label, sometimes did not specify the anxiety phenotype, and reported behavioral activation. Citalopram and buspirone yielded some improvement, whereas fluvoxamine did not. 

Non-psychopharmacological studies were mainly randomized controlled trials (RCTs) with CBT demonstrating moderate efficacy for anxiety disorders in youth with high functioning ASD. 

Deep pressure and neurofeedback provided some benefit. 

All studies were short-term and included small sample sizes. Large scale and long term RCTs examining psychopharmacological and non-psychopharmacological treatments are sorely needed.
AD  - [Vasa, Roma A.; Mahajan, Rajneesh] Kennedy Krieger Inst, Baltimore, MD 21211 USA. [Vasa, Roma A.; Mahajan, Rajneesh] Johns Hopkins Univ, Sch Med, Dept Psychiat &amp; Behav Sci, Baltimore, MD 21287 USA. [Carroll, Laura M.] Johns Hopkins Univ, Baltimore, MD 21218 USA. [Nozzolillo, Alixandra A.] Massachusetts Gen Hosp Children, Ctr Child &amp; Adolescent Hlth Res &amp; Policy, Boston, MA 02114 USA. [Mazurek, Micah O.] Univ Missouri, Dept Hlth Psychol, Columbia, MO 65212 USA. [Mazurek, Micah O.] Thompson Ctr Autism &amp; Neurodev Disorders, Columbia, MO 65201 USA. [Bennett, Amanda E.] Childrens Hosp Philadelphia, Div Dev &amp; Behav Pediat, Philadelphia, PA 19104 USA. [Wink, Logan K.] Cincinnati Childrens Hosp Med Ctr, Div Child &amp; Adolescent Psychiat, Cincinnati, OH 45229 USA. [Bernal, Maria Pilar] Stanford Univ, Dept Psychiat &amp; Behav Sci, Stanford, CA 94304 USA. [Bernal, Maria Pilar] Permanente Med Grp Inc, Oakland, CA USA. Vasa, RA (reprint author), Kennedy Krieger Inst, 3901 Greenspring Ave, Baltimore, MD 21211 USA. vasa@kennedykrieger.org
AN  - WOS:000344806500023
AU  - Vasa,
AU  - R.
AU  - A.
AU  - Carroll,
AU  - L.
AU  - M.
AU  - Nozzolillo,
AU  - A.
AU  - A.
AU  - Mahajan,
AU  - R.
AU  - Mazurek,
AU  - M.
AU  - O.
AU  - Bennett,
AU  - A.
AU  - E.
AU  - Wink,
AU  - L.
AU  - K.
AU  - Bernal,
AU  - M.
AU  - P.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10803-014-2184-9
J2  - J. Autism Dev. Disord.
KW  - Anxiety Autism spectrum disorders Treatments Children Adolescents COGNITIVE-BEHAVIORAL THERAPY PERVASIVE DEVELOPMENTAL DISORDERS HIGH-FUNCTIONING AUTISM RANDOMIZED CONTROLLED-TRIAL INTELLECTUAL DISABILITY PSYCHOMETRIC PROPERTIES CHILDHOOD ANXIETY OPEN-L
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AT3AM Times Cited: 1 Cited Reference Count: 68 Vasa, Roma A. Carroll, Laura M. Nozzolillo, Alixandra A. Mahajan, Rajneesh Mazurek, Micah O. Bennett, Amanda E. Wink, Logan K. Bernal, Maria Pilar 1 SPRINGER/PLENUM PUBLISHERS NEW YORK J AUTISM DEV DISORD
PY  - 2014
SP  - 3215-3229
T2  - Journal of Autism and Developmental Disorders
TI  - A Systematic Review of Treatments for Anxiety in Youth with Autism Spectrum Disorders
UR  - &lt;Go to ISI&gt;://WOS:000344806500023http://link.springer.com/article/10.1007%2Fs10803-014-2184-9http://download.springer.com/static/pdf/93/art%253A10.1007%252Fs10803-014-2184-9.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10803-014-2184-9&amp;token2=exp=1435232091~acl=%2Fstatic%2Fpdf%2F93%2Fart%25253A10.1007%25252Fs10803-014-2184-9.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10803-014-2184-9*~hmac=3e491ce20cf68b97e5931c688a31e691e4ea34d60e195adec08e19c1a36c2548
UR  - https://link.springer.com/article/10.1007%2Fs10803-014-2184-9
VL  - 44
ER  -
TY  - JOUR
AB  - **Background **
Thalassaemia is a group of genetic blood disorders characterised by the absence or reduction in the production of haemoglobin. Severity is variable from less severe anaemia, through thalassaemia intermedia, to profound severe anaemia (thalassaemia major). In thalassaemia major other complications include growth retardation, bone deformation, and enlarged spleen. Blood transfusion is required to treat severe forms of thalassaemia, but this results in excessive accumulation of iron in the body (iron overload), removed mostly by a drug called desferrioxamine through &#039;chelation therapy&#039;. Non-routine treatments are bone marrow transplantation (which is age restricted), and possibly hydroxyurea, designed to raise foetal haemoglobin level, thus reducing anaemia. In addition, psychological therapies seem appropriate to improving outcome and adherence to medical treatment. 

 **Objectives  **
To examine the evidence that in people with thalassaemia, psychological treatments improve the ability to cope with the condition, and improve both medical and psychosocial outcomes. 

 **Search methods  **
We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Haemoglobinopathies Trials Register which comprises of references identified from comprehensive electronic database searches and handsearches of relevant journals and abstract books of conference proceedings. Searches on the Internet were also performed. Date of the most recent search of the Group&#039;s Haemoglobinopathies Trials Register: 11 November 2013. 

 **Selection criteria  **
All randomised or quasi-randomised controlled trials comparing the use of psychological intervention to no (psychological) intervention in people with thalassaemia. 

 **Data collection and analysis  **
No trials of psychological therapies have been found in the literature for inclusion in this review. Main results There are currently no results to be reported. 

 **Authors&#039; conclusions  **
As a chronic disease with a considerable role for self-management, psychological support seems appropriate for managing thalassaemia. However, from the information currently available, no conclusions can be made about the use of specific psychological therapies in thalassaemia. This systematic review has clearly identified the need for well-designed, adequately-powered, multicentre, randomised controlled trials assessing the effectiveness of specific psychological interventions for thalassaemia.
AD  - [Anie, Kofi A.] North West London Hosp NHS Trust, Haematol &amp; Sickle Cell Ctr, London NW10 7NS, England. [Massaglia, Pia] Univ Turin, Dipartimento Sci Pediat &amp; Adolescenza, Turin, Italy. Anie, KA (reprint author), North West London Hosp NHS Trust, Cent Middlesex Hosp, Haematol &amp; Sickle Cell Ctr, Acton Lane, London NW10 7NS, England. kofi.anie@nhs.net
AN  - WOS:000333667500013
AU  - Anie,
AU  - K.
AU  - A.
AU  - Massaglia,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD002890
J2  - Cochrane Database Syst Rev.
KW  - Psychotherapy Adaptation, Psychological Blood Transfusion Chelation Therapy Iron Chelating Agents [therapeutic use] beta-Thalassemia [psychology therapy] Adult Child Humans IRON-CHELATION-THERAPY DEFEROXAMINE Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AE0PF Times Cited: 0 Cited Reference Count: 15 Anie, Kofi A. Massaglia, Pia WILEY-BLACKWELL HOBOKEN COCHRANE DB SYST REV
PY  - 2014
SP  - 14
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological therapies for thalassaemia
UR  - &lt;Go to ISI&gt;://WOS:000333667500013http://onlinelibrary.wiley.com/store/10.1002/14651858.CD002890.pub2/asset/CD002890.pdf?v=1&amp;t=ib7szg1f&amp;s=b0673f6ca2b605d4c03dfd2c7c7c79fb18bd0fc5
ER  -
TY  - JOUR
AB  - **Background:** 
The &#039;Theory of Mind&#039; (ToM) model suggests that people with autism spectrum disorder (ASD) have a profound difficulty understanding the minds of other people - their emotions, feelings, beliefs, and thoughts. As an explanation for some of the characteristic social and communication behaviours of people with ASD, this model has had a significant influence on research and practice. It implies that successful interventions to teach ToM could, in turn, have far-reaching effects on behaviours and outcome.

**Objectives:** 
To review the efficacy of interventions based on the ToM model for individuals with ASD.Search methods: In August 2013 we searched CENTRAL, Ovid MEDLINE, Embase, CINAHL, PsycINFO, ERIC, Social Services Abstracts, AutismData, and two trials registers. We also searched the reference lists of relevant papers, contacted authors who work in this field, and handsearched a number of journals.

**Selection criteria:** 
Review studies were selected on the basis that they reported on an applicable intervention (linked to ToM in one of four clearly-defined ways), presented new randomised controlled trial data, and participants had a confirmed diagnosis of an autism spectrum disorder. Studies were selected by two review authors independently and a third author arbitrated when necessary.

**Data collection and analysis:** 
Risk of bias was evaluated and data were extracted by two review authors independently; a third author arbitrated when necessary. Most studies were not eligible for meta-analysis, the principal reason being mis-matching methodologies and outcome measures. Three small meta-analyses were carried out.

**Main results:** 
Twenty-two randomised trials were included in the review (N = 695). Studies were highly variable in their country of origin, sample size, participant age, intervention delivery type, and outcome measures. Risk of bias was variable across categories. There were very few studies for which there was adequate blinding of participants and personnel, and some were also judged at high risk of bias in blinding of outcome assessors. There was also evidence of some bias in sequence generation and allocation concealment. Not all studies reported data that fell within the pre-defined primary outcome categories for the review, instead many studies reported measures which were intervention-specific (e.g. emotion recognition). The wide range of measures used within each outcome category and the mixed results from these measures introduced further complexity when interpreting results. Studies were grouped into four main categories according to intervention target/primary outcome measure. These were: emotion recognition studies, joint attention and social communication studies, imitation studies, and studies teaching ToM itself. Within the first two of these categories, a sub-set of studies were deemed suitable for meta-analysis for a limited number of key outcomes.There was very low quality evidence of a positive effect on measures of communication based on individual results from three studies. There was low quality evidence from 11 studies reporting mixed results of interventions on measures of social interaction, very low quality evidence from four studies reporting mixed results on measures of general communication, and very low quality evidence from four studies reporting mixed results on measures of ToM ability. &nbsp;The meta-analysis results we were able to generate showed that interventions targeting emotion recognition across age groups and working with people within the average range of intellectual ability had a positive effect on the target skill, measured by a test using photographs of faces (mean increase of 0.75 points, 95% confidence interval (CI) 0.22 to 1.29 points, Z = 2.75, P &lt; 0.006, four studies, N = 105). Therapist-led joint attention interventions can promote production of more joint attention behaviours within adult-child interaction (mean increase of 0.55 points, 95% CI 0.11 to 0.99 points, Z = 2.45, P value = 0.01, two studies, N = 88). Further analysis undermines this conclusion somewhat by d monstrating that there was no clear evidence that intervention can have an effect on joint attention initiations as measured using a standardised assessment tool (mean increase of 0.23 points, 95% CI -0.48 to 0.94 points, Z = 0.63, P value = 0.53, three studies, N = 92). No adverse effects were apparent.

**Authors&#039; conclusions:** 
While there is some evidence that ToM, or a precursor skill, can be taught to people with ASD, there is little evidence of maintenance of that skill, generalisation to other settings, or developmental effects on related skills. Furthermore, inconsistency in findings and measurement means that evidence has been graded of &#039;very low&#039; or &#039;low&#039; quality and we cannot be confident that suggestions of positive effects will be sustained as high-quality evidence accumulates. Further longitudinal designs and larger samples are needed to help elucidate both the efficacy of ToM-linked interventions and the explanatory value of the ToM model itself. It is possible that the continuing refinement of the ToM model will lead to better interventions which have a greater impact on development than those investigated to date.
AN  - CD008785
AU  - Fletcher-Watson,
AU  - S.
AU  - McConnell,
AU  - F.
AU  - Manola,
AU  - E.
AU  - McConachie,
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd008785.pub2
KW  - Theory of Mind
KW  - Child Development Disorders, Pervasive [psychology] [therapy]
KW  - Emotions
KW  - Randomized Controlled Trials as Topic
KW  - Humans[checkword]
KW  - Behav
PY  - 2014
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions based on the Theory of Mind cognitive model for autism spectrum disorder (ASD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008785.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD008785.pub2/asset/CD008785.pdf?v=1&amp;t=iw7jtj75&amp;s=b6c65fda7856ff209e13df49dbe8d92a0a094b26
ER  -
TY  - JOUR
AB  - Relationship-based intervention programs are increasingly being implemented as a way to enhance parent-child interaction quality. In this meta-analytic review, we examined the effectiveness of 19 recent relationship-based interventions serving socioeconomically disadvantaged families with infants and toddlers (N = 6,807). 

This review specifically focused on intervention effectiveness in terms of improving supportive parenting behaviors, as measured by observational assessments of dyadic parent-child interactions. Meta-analytic results indicated significant, yet modest, effectiveness across all interventions (d = .23). 

Intervention characteristics such as participant randomization, breadth of intervention services offered, duration, child age at the start of the intervention, professional qualifications of the intervenor, and type of play task used during assessment were tested as possible moderators of effectiveness.

Significant differences in effectiveness were found between randomized and nonrandomized interventions. Within the subsample of randomized interventions, programs that were shorter in duration, that provided direct services to the parent-child dyad, used intervenors with professional qualifications, and assessed parent-child interactions with free-play tasks were the most effective, highlighting important considerations for designing effective intervention protocol tailored to the needs of this high-risk population.

&copy; 2014 Michigan Association for Infant Mental Health.
AD  - Mortensen, Jennifer A. University of Arizona.
AN  - 25798486
AU  - Mortensen,
AU  - J.
AU  - A.
AU  - Mastergeorge,
AU  - A.
AU  - M.
DA  - Jul-Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/imhj.21451
DP  - Ovid Technologies
J2  - Infant Ment Health J
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - *Parent-Child Relations
KW  - Parenting
KW  - Parents
KW  - *Poverty
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://1204389502/Mortensen-2014-A meta-analytic review of relat.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Mortensen, Jennifer A Mastergeorge, Ann M
PY  - 2014
SP  - 336-53
T2  - Infant Mental Health Journal
TI  - A meta-analytic review of relationship-based interventions for low-income families with infants and toddlers: facilitating supportive parent-child interactions
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25798486http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25798486&amp;id=doi:10.1002%2Fimhj.21451&amp;issn=0163-9641&amp;isbn=&amp;volume=35&amp;issue=4&amp;spage=336&amp;pages=336-53&amp;date=2014&amp;title=Infant+Mental+Health+Journal&amp;atitle=A+meta-analytic+review+of+relationship-based+interventions+for+low-income+families+with+infants+and+toddlers%3A+facilitating+supportive+parent-child+interactions.&amp;aulast=Mortensen&amp;pid=%3Cauthor%3EMortensen+JA%3C%2Fauthor%3E%3CAN%3E25798486%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/doi/10.1002/imhj.21451/abstract?systemMessage=Pay+per+view+article+purchase%28PPV%29+on+Wiley+Online+Library+will+be+unavailable+on+Saturday+11th+March+from+05%3A00-14%3A00+GMT+%2F+12%3A00-09%3A00+EST+%2F+13%3A00-22%3A00+SGT+for+essential+maintenance.++Apologies+for+the+inconvenience.
UR  - http://onlinelibrary.wiley.com/store/10.1002/imhj.21451/asset/imhj21451.pdf?v=1&amp;t=j02jmz99&amp;s=d2e66501b6d0ff3d2471dbbdffc7a5bd380f9094
VL  - 35
ER  -
TY  - JOUR
AB  - **Objective: **
This study compared the effects of direct child-parent interventions to the effects of child-focused interventions on anxiety outcomes for children with anxiety disorders. 

**Method: **
Systematic review methods and meta-analytic techniques were employed. Eight randomized controlled trials examining effects of family cognitive behavior therapy compared to individual or group child-only therapy met criteria. 

**Results: **
The overall mean effect of parent-child interventions was 0.26, 95% confidence interval [0.05, 0.47], p &lt; .05, a small but positive and significant effect, favoring child-parent interventions. Results of the heterogeneity analysis were not significant (Q = 8.08, df = 7, p &gt; .05, I-2 = 13.41). 

**Discussion:** 
Parent-child interventions appear to be more effective than child-focused individual and group cognitive behavioral therapy in treating childhood anxiety disorders. Implications for practice and research are discussed.
AD  - [Brendel, Kristen Esposito] Aurora Univ, Sch Social Work, Aurora, IL 60506 USA. [Maynard, Brandy R.] St Louis Univ, Sch Social Work, St Louis, MO 63103 USA. Brendel, KE (reprint author), Aurora Univ, Sch Social Work, 347 Gladstone, Aurora, IL 60506 USA. kbrendel@aurora.edu
AN  - WOS:000336526800002
AU  - Brendel,
AU  - K.
AU  - E.
AU  - Maynard,
AU  - B.
AU  - R.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1049731513503713
J2  - Res. Soc. Work. Pract.
KW  - anxiety disorder systematic review meta-analysis family cognitive behavioral therapy COGNITIVE-BEHAVIORAL THERAPY FAMILY TREATMENT FUTURE-DIRECTIONS ADOLESCENTS PSYCHOTHERAPY COMORBIDITY INVOLVEMENT PREVALENCE EFFICACY TRIAL Social Work
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AI0HK Times Cited: 0 Cited Reference Count: 54 Brendel, Kristen Esposito Maynard, Brandy R. SAGE PUBLICATIONS INC THOUSAND OAKS RES SOCIAL WORK PRAC
PY  - 2014
SP  - 287-295
T2  - Research on Social Work Practice
TI  - Child-Parent Interventions for Childhood Anxiety Disorders: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000336526800002http://rsw.sagepub.com/content/24/3/287http://rsw.sagepub.com/content/24/3/287.full.pdf
VL  - 24
ER  -
TY  - JOUR
AB  - **Objective: **
To compare the incidence of adverse events between active and placebo arms of randomized clinical trials in depressive children and adolescents (C&amp;A) with antidepressant treatments, in order to look for similarities in both groups that allow to establish a possible nocebo effect. 

**Methods: **
Systematic search strategy (January 1974-March 2013) in electronic databases, conference abstracts, and reference list of systematic reviews and included studies to identify parallel randomized placebo-controlled trials of antidepressants in C&amp;A (&lt;19 years) with major depressive disorder, and one or more interventions of any orally administered antidepressant. The pooled adverse events were calculated based on a fixed-effect model and statistical analysis involved the risk ratio (RR) of adverse events, with 95% confidence intervals (95% CI). 

**Results: **
Sixteen studies were included in the review, of which seven studies with a sample of 1911 patients had data to include in the meta-analysis. There was similar risk for the incidence of adverse events between non-active and active group (global RR 1.04, 95% CI: 0.97-1.11). 

**Conclusion: **
Depressive C&amp;A allocated to placebo or active group had similar risk to develop adverse events. These similarities in both groups are attributed to the nocebo effect. It is of note that defining &quot;nocebo&quot; effects is challenging in clinical populations because adverse effects may be attributed to the intervention or may be manifestation of the disease itself. The inclusion of a no-treatment arm may be warranted. Nocebo effects are likely when adverse events of placebo mimic the adverse events of active treatment, as was the case here. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Linnman, Clas: clas.linnman@childrens.harvard.edu Linnman, Clas: Pain and Analgesia Imaging Neuroscience (P.A.I.N.) Group, Department of Anesthesiology, Perioperative and Pain Medicine, Center for Pain and the Brain, Boston Children&#039;s Hospital, Harvard Medical School, 9 Hope Avenue, Waltham, MA, US, 02453, clas.linnman@childrens.harvard.edu Rojas-Mirquez, Johanna Carolina: Pain and Analgesia Imaging Neuroscience (P.A.I.N.) Group, Department of Anesthesiology, Perioperative and Pain Medicine, Center for Pain and the Brain, Boston Children&#039;s Hospital, Harvard Medical School, Waltham, MA, US Rodriguez-Zuniga, Milton Jose Max: Pain and Analgesia Imaging Neuroscience (P.A.I.N.) Group, Department of Anesthesiology, Perioperative and Pain Medicine, Center for Pain and the Brain, Boston Children&#039;s Hospital, Harvard Medical School, Waltham, MA, US Bonilla-Escobar, Francisco Javier: Instituto Cisalva, School of Public Health, Universidad del Valle, Cali, Colombia Garcia-Perdomo, Herney Andres: Cochrane Center, Universidad del Valle, Cali, Colombia Petkov, Mike: Pain and Analgesia Imaging Neuroscience (P.A.I.N.) Group, Department of Anesthesiology, Perioperative and Pain Medicine, Center for Pain and the Brain, Boston Children&#039;s Hospital, Harvard Medical School, Waltham, MA, US Becerra, Lino: Pain and Analgesia Imaging Neuroscience (P.A.I.N.) Group, Department of Anesthesiology, Perioperative and Pain Medicine, Center for Pain and the Brain, Boston Children&#039;s Hospital, Harvard Medical School, Waltham, MA, US Borsook, David: Pain and Analgesia Imaging Neuroscience (P.A.I.N.) Group, Department of Anesthesiology, Perioperative and Pain Medicine, Center for Pain and the Brain, Boston Children&#039;s Hospital, Harvard Medical School, Waltham, MA, US Linnman, Clas: Pain and Analgesia Imaging Neuroscience (P.A.I.N.) Group, Department of Anesthesiology, Perioperative and Pain Medicine, Center for Pain and the Brain, Boston Children&#039;s Hospital, Harvard Medical School, Waltham, MA, US
AN  - 2015-05742-001
AU  - Rojas-Mirquez,
AU  - J.
AU  - C.
AU  - Rodriguez-Zuniga,
AU  - M.
AU  - J.
AU  - M.
AU  - Bonilla-Escobar,
AU  - F.
AU  - J.
AU  - Garcia-Perdomo,
AU  - H.
AU  - A.
AU  - Petkov,
AU  - M.
AU  - Becerra,
AU  - L.
AU  - Borsook,
AU  - D.
AU  - Linnman,
AU  - C.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3389/fnbeh.2014.00375
DP  - Ovid Technologies
KW  - nocebo, children, adolescents, antidepressants, meta-analysis
KW  - *Clinical Trials
KW  - *Drug Therapy
KW  - *Major Depression
KW  - *Side Effects (Drug)
KW  - Childhood Development
KW  - Placebo
KW  - Clinical Psychopharmacology [3340]
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://2354359585/Rojas-2014-Nocebo effect in randomized clinica.pdf
LA  - English
M3  - Literature Review; Meta Analysis
PY  - 2014
T2  - Frontiers in Behavioral Neuroscience
TI  - Nocebo effect in randomized clinical trials of antidepressants in children and adolescents: Systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2015-05742-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=1662-5153&amp;isbn=&amp;volume=8&amp;issue=&amp;spage=375&amp;pages=&amp;date=2014&amp;title=Frontiers+in+Behavioral+Neuroscience&amp;atitle=Nocebo+effect+in+randomized+clinical+trials+of+antidepressants+in+children+and+adolescents%3A+Systematic+review+and+meta-analysis.&amp;aulast=Rojas-Mirquez&amp;pid=%3Cauthor%3ERojas-Mirquez%2C+Johanna+Carolina%3C%2Fauthor%3E%3CAN%3E2015-05742-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://journal-cdn.frontiersin.org/article/104796/files/pubmed-zip/versions/1/pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The majority of internet-based anxiety and depression intervention studies have targeted adults. An increasing number of studies of children, youth, and young adults have been conducted, but the evidence on effectiveness has not been synthesized. The objective of this research is to systematically review the most recent findings in this area and calculate overall (pooled) effect estimates of internet-based anxiety and/or depression interventions. 

**METHODS: **
We searched five literature databases (PubMed, EMBASE, CINAHL, PsychInfo, and Google Scholar) for studies published between January 1990 and December 2012. We included studies evaluating the effectiveness of internet-based interventions for children, youth, and young adults (age &lt;25 years) with anxiety and/or depression and their parents. Two reviewers independently assessed the risk of bias regarding selection bias, allocation bias, confounding bias, blinding, data collection, and withdrawals/dropouts. We included studies rated as high or moderate quality according to the risk of bias assessment. We conducted meta-analyses using the random effects model. We calculated standardized mean difference and its 95% confidence interval (95% CI) for anxiety and depression symptom severity scores by comparing internet-based intervention vs. waitlist control and internet-based intervention vs. face-to-face intervention. We also calculated pooled remission rate ratio and 95% CI. 

**RESULTS: **
We included seven studies involving 569 participants aged between 7 and 25 years. Meta-analysis suggested that, compared to waitlist control, internet-based interventions were able to reduce anxiety symptom severity (standardized mean difference and 95% CI = -0.52 [-0.90, -0.14]) and increase remission rate (pooled remission rate ratio and 95% CI =3.63 [1.59, 8.27]). The effect in reducing depression symptom severity was not statistically significant (standardized mean difference and 95% CI = -0.16 [-0.44, 0.12]). We found no statistical difference in anxiety or depression symptoms between internet-based intervention and face-to-face intervention (or usual care). 

**CONCLUSIONS:** 
The present analysis indicated that internet-based interventions were effective in reducing anxiety symptoms and increasing remission rate, but not effective in reducing depression symptom severity. Due to the small number of higher quality studies, more attention to this area of research is encouraged. 

TRIAL REGISTRATION: PROSPERO registration: CRD42012002100.
AD  - Ye,Xibiao. Centre for Healthcare Innovation Evaluation Platform, Winnipeg Regional Health Authority, 200-1155 Concordia Avenue, Winnipeg, Manitoba R2K 2M9, Canada. xibiao.ye@gmail.com.
AN  - 25037951
AU  - Ye,
AU  - X.
AU  - Bapuji,
AU  - S.
AU  - B.
AU  - Winters,
AU  - S.
AU  - E.
AU  - Struthers,
AU  - A.
AU  - Raynard,
AU  - M.
AU  - Metge,
AU  - C.
AU  - Kreindler,
AU  - S.
AU  - A.
AU  - Charette,
AU  - C.
AU  - J.
AU  - Lemaire,
AU  - J.
AU  - A.
AU  - Synyshyn,
AU  - M.
AU  - Sutherland,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/1472-6963-14-313
DP  - Ovid Technologies
J2  - BMC Health Serv Res
KW  - Adolescent *Anxiety Disorders/th [Therapy] Child *Depressive Disorder/th [Therapy] Health Services Accessibility Humans *Internet *Psychotherapy/mt [Methods] Randomized Controlled Trials as Topic Young Adult
L1  - internal-pdf://4273683478/Ye-2014-Effectiveness of internet-based interv.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Ye, Xibiao Bapuji, Sunita Bayyavarapu Winters, Shannon Elizabeth Struthers, Ashley Raynard, Melissa Metge, Colleen Kreindler, Sara Adi Charette, Catherine Joan Lemaire, Jacqueline Angela Synyshyn, Margaret Sutherland, Karen KA1-119794 (Canada Canadian Institutes of Health Research)
PY  - 2014
SP  - 313
T2  - BMC Health Services Research
TI  - Effectiveness of internet-based interventions for children, youth, and young adults with anxiety and/or depression: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25037951
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25037951&amp;id=doi:10.1186%2F1472-6963-14-313&amp;issn=1472-6963&amp;isbn=&amp;volume=14&amp;issue=1&amp;spage=313&amp;pages=313&amp;date=2014&amp;title=BMC+Health+Services+Research&amp;atitle=Effectiveness+of+internet-based+interventions+for+children%2C+youth%2C+and+young+adults+with+anxiety+and%2For+depression%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Ye&amp;pid=%3Cauthor%3EYe+X%3C%2Fauthor%3E%3CAN%3E25037951%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110069/pdf/1472-6963-14-313.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110069/pdf/1472-6963-14-313.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - **Background:** 
The scientific literature examining effective treatments for opioid-dependent adults clearly indicates that pharmacotherapy is a necessary and acceptable component. Nevertheless, no reviews have been published that systematically assess the effectiveness of pharmacological maintenance treatment in adolescents.

**Objectives:** 
To assess the effectiveness of any maintenance treatment alone or in combination with psychosocial intervention compared to no intervention, other pharmacological intervention or psychosocial interventions for retaining adolescents in treatment, reducing the use of substances and improving health and social status.

**Search methods:** 
We searched the Cochrane Drugs and Alcohol Group&#039;s Trials Register (January 2014), the Cochrane Central Register of Controlled Trials (2014, Issue 1), PubMed (January 1966 to January 2014), EMBASE (January 1980 to January 2014), CINAHL (January 1982 to January 2014), Web of Science (1991 to January 2014) and reference lists of articles.

**Selection criteria:** 
Randomised and controlled clinical trials of any maintenance pharmacological interventions either alone or associated with psychosocial intervention compared with no intervention, placebo, other pharmacological intervention, pharmacological detoxification or psychosocial intervention in adolescents (13 to 18 years).

**Data collection and analysis:**
We used the standard methodological procedures expected by The Cochrane Collaboration.

**Main results:** 
We included two trials involving 189 participants. One study, with 35 participants, compared methadone with levo-alpha-acetylmethadol (LAAM) for maintenance treatment lasting 16 weeks, after which patients were detoxified. The other study, with 154 participants, compared maintenance treatment with buprenorphine-naloxone and detoxification with buprenorphine. We did not perform meta-analysis because the two studies assessed different comparisons.In the study comparing methadone and LAAM, the authors declared that there was no difference in the use of a substance of abuse or social functioning (data not shown). The quality of the evidence was very low. No side effects, such as nausea, vomiting, constipation, weakness or fatigue, were reported by study participants.In the comparison between buprenorphine maintenance and buprenorphine detoxification, maintenance treatment appeared to be more efficacious in retaining patients in treatment (drop-out risk ratio (RR) 0.37; 95% confidence interval (CI) 0.26 to 0.54), but not in reducing the number of patients with a positive urine test at the end of the study (RR 0.97; 95% CI 0.78 to 1.22). Self reported opioid use at one-year follow-up was significantly lower in the maintenance group, even though both groups reported a high level of opioid use (RR 0.73; 95% CI 0.57 to 0.95). More patients in the maintenance group were enrolled in other addiction treatment programmes at 12-month follow-up (RR 1.33; 95% CI 0.94 to 1.88). The quality of the evidence was low. No serious side effects attributable to buprenorphine-naloxone were reported by study participants and no patients were removed from the study due to side effects. The most common side effect was headache, which was reported by 16% to 21% of patients in both groups.

**Authors&#039; conclusions:** 
It is difficult to draft conclusions on the basis of only two trials. One of the possible reasons for the lack of evidence could be the difficulty of conducting trials with young people for practical and ethical reasons.There is an urgent need for further randomised controlled trials comparing maintenance treatment with detoxification treatment or psychosocial treatment alone before carrying out studies that compare different pharmacological maintenance treatments. These studies should have long follow-up and measure relapse rates after the end of treatment and social functioning (integration at school or at work, family relationships).
AN  - CD007210
AU  - Minozzi,
AU  - S.
AU  - Amato,
AU  - L.
AU  - Bellisario,
AU  - C.
AU  - Davoli,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007210.pub3
KW  - Buprenorphine [therapeutic use]
KW  - Maintenance Chemotherapy [methods]
KW  - Methadone [therapeutic use]
KW  - Methadyl Acetate [therapeutic use]
KW  - Naloxone [therapeutic use]
KW  - Narcotics [therapeutic use]
KW  - Opiate Substitution Treatment [methods]
KW  - Opioid-Related Disorders [rehabilitation]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Humans[checkword]
KW  - Addictn
PY  - 2014
T2  - Cochrane Database of Systematic Reviews
TI  - Maintenance treatments for opiate -dependent adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007210.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007210.pub3/asset/CD007210.pdf?v=1&amp;t=iw7k0ryc&amp;s=a6f4e73c9457f66e78a568edb87b435e45b9a31f
ER  -
TY  - JOUR
AB  - Concerns about growth retardation and unknown effects on long-term brain development with stimulants have prompted interest in polyunsaturated fatty acid supplementation (PUFA) as an alternative treatment. However, randomized controlled trials (RCTs) and meta-analyses of PUFA supplementation in ADHD have shown marginal benefit, and uncertainty exists as to which, if any, PUFA might be effective in alleviating symptoms of ADHD. 

We conducted an updated meta-analysis of RCTs in ADHD together with multivariable meta-regression analyses using data on PUFA content obtained from independent fatty acid methyl ester analyses of each study PUFA regimen. The PubMed, Embase and PsycINFO databases were searched with no start date and up to 28th July 2013. 

Study inclusion criteria were: randomized design, placebo controlled, PUFA preparation as active intervention, reporting change scores on ADHD rating-scale measures. Rating-scale measures of inattention and hyperactive-impulsive symptoms were extracted, study authors were contacted to obtain missing data, studies not reporting negative findings had these data imputed, and study quality was assessed using the Jadad system plus other indicators. 

Random-effects models were used for pooled effects and for meta-regression analyses. Standardized mean differences (SMD) in inattention, hyperactive-impulsive and combined symptoms were assessed as rated by parents, teachers or all raters. The influence of study characteristics and PUFA regimen content was explored in multivariable meta-regression analyses. The overall pooled estimate from 18 studies showed that combined ADHD symptoms rated by all raters decreased with PUFA supplementation; SMD -0.192 (95% CI: -0.297, -0.086; P&lt;0.001). 

However, when analyzed by rater, only parent-rated symptoms decreased significantly. Multivariable meta-regression showed that longer study duration, -linolenic acid (GLA), and the interaction between GLA and eicosapentaenoic acid (EPA) were associated with significant decreases in inattention; however, PUFA regimen content was unrelated to changes in hyperactive-impulsive symptoms. Certain fatty acids present in placebo preparations may potentially have been psychoactive. 

This meta-analysis provides modest evidence of PUFA effectiveness in ADHD, especially GLA and EPA for inattention symptoms; however, evidence of reporting bias, publication bias, variable methodological quality, and use of potentially psychoactive placebos limit the generalizability of these findings. 

Copyright &copy; 2014 Elsevier Ltd. All rights reserved.
AD  - Puri,Basant K. Department of Medicine and Department of Imaging, Hammersmith Hospital, Imperial College London, Du Cane Road, London W12 0HS, England, UK. Electronic address: basant.puri@imperial.ac.uk. Martins,Julian G. Academy of Nutritional Medicine, 80 Commercial End, Swaffham Bulbeck, Cambridge CB25 0NE, UK.
AN  - 24560325
AU  - Puri,
AU  - B.
AU  - K.
AU  - Martins,
AU  - J.
AU  - G.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.plefa.2014.01.004
DP  - Ovid Technologies
J2  - Prostaglandins Leukot Essent Fatty Acids
KW  - Adolescent *Attention/de [Drug Effects] Attention Deficit Disorder with Hyperactivity/dh [Diet Therapy] Attention Deficit Disorder with Hyperactivity/pp [Physiopathology] *Attention Deficit Disorder with Hyperactivity Child Child, Preschool *Eicosapenta
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Puri, Basant K Martins, Julian G S0952-3278(14)00018-0
PY  - 2014
SP  - 179-89
T2  - Prostaglandins Leukotrienes &amp; Essential Fatty Acids
TI  - Which polyunsaturated fatty acids are active in children with attention-deficit hyperactivity disorder receiving PUFA supplementation? A fatty acid validated meta-regression analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24560325 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24560325&amp;id=doi:10.1016%2Fj.plefa.2014.01.004&amp;issn=0952-3278&amp;isbn=&amp;volume=90&amp;issue=5&amp;spage=179&amp;pages=179-89&amp;date=2014&amp;title=Prostaglandins+Leukotrienes+%26+Essential+Fatty+Acids&amp;atitle=Which+polyunsaturated+fatty+acids+are+active+in+children+with+attention-deficit+hyperactivity+disorder+receiving+PUFA+supplementation%3F+A+fatty+acid+validated+meta-regression+analysis+of+randomized+controlled+trials.&amp;aulast=Puri&amp;pid=%3Cauthor%3EPuri+BK%3C%2Fauthor%3E%3CAN%3E24560325%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0952327814000180/1-s2.0-S0952327814000180-main.pdf?_tid=cf995ab8-18ac-11e5-90aa-00000aab0f01&amp;acdnat=1434956800_b93fb2ab11b7798195610c63cc544ce1
VL  - 90
ER  -
TY  - JOUR
AB  - **Background: **
Greater access to evidence-based psychological treatments is needed. This review aimed to evaluate whether internet-delivered psychological treatments for mood and anxiety disorders are efficacious, noninferior to established treatments, safe, and cost-effective for children, adolescents and adults. 

**Methods: **
We searched the literature for studies published until March 2013. Randomized controlled trials (RCTs) were considered for the assessment of short-term efficacy and safety and were pooled in meta-analyses. Other designs were also considered for long-term effect and cost-effectiveness. Comparisons against established treatments were evaluated for noninferiority. Two reviewers independently assessed the relevant studies for risk of bias. The quality of the evidence was graded using an international grading system. 

**Results: **
A total of 52 relevant RCTs were identified whereof 12 were excluded due to high risk of bias. Five cost-effectiveness studies were identified and three were excluded due to high risk of bias. The included trials mainly evaluated internet-delivered cognitive behavioral therapy (I-CBT) against a waiting list in adult volunteers and 88% were conducted in Sweden or Australia. One trial involved children. For adults, the quality of evidence was graded as moderate for the short-term efficacy of I-CBT vs. waiting list for mild/moderate depression (d = 0.83; 95% CI 0.59, 1.07) and social phobia (d = 0.85; 95% CI 0.66, 1.05), and moderate for no efficacy of internet-delivered attention bias modification vs. sham treatment for social phobia (d = 20.04; 95% CI 20.24, 0.35). The quality of evidence was graded as low/very low for other disorders, interventions, children/adolescents, noninferiority, adverse events, and cost-effectiveness. 

**Conclusions: **
I-CBT is a viable treatment option for adults with depression and some anxiety disorders who request this treatment modality. Important questions remain before broad implementation can be supported. Future research would benefit from prioritizing adapting treatments to children/adolescents and using noninferiority designs with established forms of treatment.
AD  - [Arnberg, Filip K.] Uppsala Univ, Dept Neurosci, Uppsala, Sweden. [Linton, Steven J.] Univ Orebro, Dept Law Psychol &amp; Social Work, Ctr Hlth &amp; Med Psychol, SE-70182 Orebro, Sweden. [Hultcrantz, Monica; Heintz, Emelie; Jonsson, Ulf] Swedish Council Hlth Technol Assessment, Stockholm, Sweden. [Heintz, Emelie] Linkoping Univ, Dept Med &amp; Hlth Sci, Ctr Med Technol Assessment CMT, Linkoping, Sweden. [Jonsson, Ulf] Karolinska Inst, Dept Clin Neurosci, Div Insurance Med, Stockholm, Sweden. Arnberg, FK (reprint author), Uppsala Univ, Dept Neurosci, Uppsala, Sweden. filip.arnberg@neuro.uu.se
AN  - WOS:000339563400097
AU  - Arnberg,
AU  - F.
AU  - K.
AU  - Linton,
AU  - S.
AU  - J.
AU  - Hultcrantz,
AU  - M.
AU  - Heintz,
AU  - E.
AU  - Jonsson,
AU  - U.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0098118
J2  - PLoS One
KW  - RANDOMIZED CONTROLLED-TRIAL COGNITIVE-BEHAVIOR THERAPY UNGUIDED SELF-HELP SOCIAL PHOBIA PANIC DISORDER FOLLOW-UP MENTAL-DISORDERS CLINICAL-TRIALS NON-INFERIORITY PRIMARY-CARE Multidisciplinary Sciences
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AM0UW Times Cited: 2 Cited Reference Count: 98 Arnberg, Filip K. Linton, Steven J. Hultcrantz, Monica Heintz, Emelie Jonsson, Ulf Swedish Council on Health Technology Assessment This work was funded by the Swedish Council on Health Technology Assessment (www.sbu.se). The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. 2 PUBLIC LIBRARY SCIENCE SAN FRANCISCO PLOS ONE
PY  - 2014
SP  - 13
T2  - Plos One
TI  - Internet-Delivered Psychological Treatments for Mood and Anxiety Disorders: A Systematic Review of Their Efficacy, Safety, and Cost-Effectiveness
UR  - &lt;Go to ISI&gt;://WOS:000339563400097http://www.plosone.org/article/fetchObject.action?uri=info:doi/10.1371/journal.pone.0098118&amp;representation=PDF
VL  - 9
ER  -
TY  - JOUR
AB  - Interest in the value of omega-3 (n-3) fatty acid supplementation for treatment of ADHD remains high. No prior meta-analysis has examined whether ADHD is associated with alterations in blood lipid levels and meta-analyses of supplementation have reached conflicting conclusions. 

**METHODS: **
We report two new meta-analyses. Study 1 examined blood levels of omega-3 fatty acids in relation to ADHD. Study 2 examined a larger sample of randomized intervention trials than previously reported. 

**RESULTS: **
Study 1 included 9 studies (n=586) and found lower overall blood levels of n-3 in individuals with ADHD versus controls (g=0.42, 95% CI=0.26-0.59; p&lt;.001). Study 2 included 16 studies (n=1408) and found that n-3 supplementation improved ADHD composite symptoms; using the best available rating and reporter (g=0.26, 95% CI=0.15-0.37; p&lt;.001). Supplementation showed reliable effects on hyperactivity by parent and teacher report, but reliable effects for inattention only by parent report. 

**CONCLUSIONS: **
Omega-3 levels are reduced in children with ADHD. Dietary supplementation appears to create modest improvements in symptoms. There is sufficient evidence to consider omega-3 fatty acids as a possible supplement to established therapies. However it remains unclear whether such intervention should be confined to children with below normal blood levels.

Copyright &copy; 2014 Elsevier Ltd. All rights reserved.
AD  - Hawkey,Elizabeth. Department of Behavioral Neuroscience, School of Medicine, Oregon Health &amp; Science University, Portland, OR, United States. Nigg,Joel T. Department of Behavioral Neuroscience, School of Medicine, Oregon Health &amp; Science University, Portland, OR, United States; Department of Psychiatry, School of Medicine, Oregon Health &amp; Science University, Portland, OR, United States. Electronic address: niggj@ohsu.edu.
AN  - 25181335
AU  - Hawkey,
AU  - E.
AU  - Nigg,
AU  - J.
AU  - T.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2014.05.005
DP  - Ovid Technologies
J2  - Clin Psychol Rev
L1  - internal-pdf://2965880872/Hawkey-2014-Omega-3 fatty acid and ADHD_ blood.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Hawkey, Elizabeth Nigg, Joel T S0272-7358(14)00074-9 R01 MH059105 (United States NIMH NIH HHS)
PY  - 2014
SP  - 496-505
T2  - Clinical Psychology Review
TI  - Omega-3 fatty acid and ADHD: blood level analysis and meta-analytic extension of supplementation trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25181335 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25181335&amp;id=doi:10.1016%2Fj.cpr.2014.05.005&amp;issn=0272-7358&amp;isbn=&amp;volume=34&amp;issue=6&amp;spage=496&amp;pages=496-505&amp;date=2014&amp;title=Clinical+Psychology+Review&amp;atitle=Omega-3+fatty+acid+and+ADHD%3A+blood+level+analysis+and+meta-analytic+extension+of+supplementation+trials.&amp;aulast=Hawkey&amp;pid=%3Cauthor%3EHawkey+E%3C%2Fauthor%3E%3CAN%3E25181335%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735814000749/1-s2.0-S0272735814000749-main.pdf?_tid=3861c52e-1972-11e5-a8d4-00000aacb35f&amp;acdnat=1435041586_ced847e75cc464c2af7070a9913efccf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321799/pdf/nihms-660144.pdf
VL  - 34
ER  -
TY  - JOUR
AB  - This meta-analysis aims to inform clinical practice of treatment strategies for adolescents with major depressive disorder (MDD). 

The efficacy of three empirically validated treatments was compared to determine the most effective treatment. These were: cognitive-behavioural therapy (CBT), selective serotonin reuptake inhibitor (SSRI) pharmacotherapy, and combination CBT and SSRI therapy. Inclusion criteria required studies to report a reliable and valid pre- and post-treatment measure and adequate data for Hedge&#039;s g effect size to be calculated. 

Forty-nine studies meeting the above inclusion criteria were found and included in the analysis. 

Although all three treatment strategies were found to be effective, analysis revealed no significant difference in treatment outcome among CBT, SSRI, and combination therapy. 
An investigation of moderator variables revealed months to follow-up to significantly influence the relationship between treatment type and treatment outcome. 

Given that CBT has no side effects, is more cost effective, and is equally as effective as SSRI therapy and combination therapy, the current study makes a strong case for CBT as a first-line treatment strategy for adolescents with MDD. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Singh, Nikita: nikita_s@hotmail.com Singh, Nikita, nikita_s@hotmail.com Singh, Nikita: Department of Psychology, RMIT University, Bundoora, VIC, Australia Reece, John: Department of Psychology, RMIT University, Bundoora, VIC, Australia
AN  - 2014-29011-005
AU  - Singh,
AU  - N.
AU  - Reece,
AU  - J.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1017/edp.2013.20
DP  - Ovid Technologies
KW  - treatment outcomes, psychotherapy, pharmacotherapy, adolescents, major depressive disorder, clinical practice, treatment strategies *Clinical Practice *Drug Therapy *Major Depression *Psychotherapy *Treatment Outcomes Health &amp; Mental Health Treatment &amp;
LA  - English
M3  - Meta Analysis
PY  - 2014
SP  - 47-65
T2  - The Australian Educational and Developmental Psychologist
TI  - Psychotherapy, pharmacotherapy, and their combination for adolescents with major depressive disorder: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2014-29011-005 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1017%2Fedp.2013.20&amp;issn=0816-5122&amp;isbn=&amp;volume=31&amp;issue=1&amp;spage=47&amp;pages=47-65&amp;date=2014&amp;title=The+Australian+Educational+and+Developmental+Psychologist&amp;atitle=Psychotherapy%2C+pharmacotherapy%2C+and+their+combination+for+adolescents+with+major+depressive+disorder%3A+A+meta-analysis.&amp;aulast=Singh&amp;pid=%3Cauthor%3ESingh%2C+Nikita%3C%2Fauthor%3E%3CAN%3E2014-29011-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://journals.cambridge.org/action/displayAbstract?fromPage=online&amp;aid=9296920&amp;fileId=S0816512213000205http://journals.cambridge.org/download.php?file=%2FEDP%2FEDP31_01%2FS0816512213000205a.pdf&amp;code=446c2cb9b2f0c5770e7fa9d615b280fd
VL  - 31
ER  -
TY  - JOUR
AB  - We systematically searched 9 biomedical and social science databases (1980-2012) for primary and secondary interventions that prevented or reduced 2 or more adolescent health risk behaviors (tobacco use, alcohol use, illicit drug use, risky sexual behavior, aggressive acts). 

We identified 44 randomized controlled trials of universal or selective interventions and were effective for multiple health risk behaviors. Most were school based, conducted in the United States, and effective for multiple forms of substance use. 

Effects were small, in line with findings for other universal prevention programs. In some studies, effects for more than 1 health risk behavior only emerged at long-term follow-up. Integrated prevention programs are feasible and effective and may be more efficient than discrete prevention strategies. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Hale, Daniel R.: daniel.hale@ucl.ac.uk Hale, Daniel R.: General and Adolescent Paediatrics Unit, Institute of Child Health, University College London, 30 Guilford St, London, United Kingdom, WC1N 1EH, daniel.hale@ucl.ac.uk Hale, Daniel R.: General and Adolescent Paediatrics Unit, Institute of Child Health, University College London, London, United Kingdom Fitzgerald-Yau, Natasha: General and Adolescent Paediatrics Unit, Institute of Child Health, University College London, London, United Kingdom Viner, Russell Mark: General and Adolescent Paediatrics Unit, Institute of Child Health, University College London, London, United Kingdom
AN  - 2014-13838-007
AU  - Hale,
AU  - D.
AU  - R.
AU  - Daniel,
AU  - R.
AU  - Fitzgerald-Yau,
AU  - N.
AU  - Viner,
AU  - R.
AU  - M.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2105/AJPH.2014.301874
DP  - Ovid Technologies
KW  - effective interventions, health risk behaviors, adolescence, randomized controlled trials, prevention programs
KW  - *Clinical Trials
KW  - *Developmental Age Groups
KW  - *Intervention
KW  - *Prevention
KW  - *Risk Factors
KW  - Health Behavior
KW  - Promotion &amp; Maintenance of Health &amp; Wellness [3365]
KW  - Adolescent
KW  - Adolescent Behavior
KW  - Adult
KW  - Aggression
KW  - Child
KW  - Family
KW  - Health Promotion
KW  - Humans
KW  - Internet
KW  - Randomized Controlled Trials as Topic
KW  - Residence Characteristics
KW  - Risk-Taking
KW  - Schools
KW  - Sexual Behavior
KW  - Socioeconomic Factors
KW  - Substance-Related Disorders
KW  - Young Adult
KW  - Human Adolescence (13-17 yrs)
KW  - us
L1  - internal-pdf://0570095375/Hale-2014-A systematic review of effective int.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2014
SP  - e19-e41
T2  - American Journal of Public Health
TI  - A systematic review of effective interventions for reducing multiple health risk behaviors in adolescence
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2014-13838-007http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.2105%2FAJPH.2014.301874&amp;issn=0090-0036&amp;isbn=&amp;volume=104&amp;issue=5&amp;spage=e19&amp;pages=e19-e41&amp;date=2014&amp;title=American+Journal+of+Public+Health&amp;atitle=A+systematic+review+of+effective+interventions+for+reducing+multiple+health+risk+behaviors+in+adolescence.&amp;aulast=Hale&amp;pid=%3Cauthor%3EHale%2C+Daniel+R%3C%2Fauthor%3E%3CAN%3E2014-13838-007%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987586/pdf/AJPH.2014.301874.pdf
VL  - 104
ER  -
TY  - JOUR
AB  - Engagement in aggressive behavior has been associated with many negative outcomes for children including academic failure, social maladjustment, peer rejection, and lifelong destructive and criminal behavior. 

Cognitive-behavioral interventions (CBIs), which use behavioral principles, behavior therapy, and cognitive mediation through self-talk, are one type of intervention used to decrease aggressive behavior in school populations. 

The purposes of this meta-analysis are to examine the effectiveness of school-based CBIs in reducing or preventing aggression in children and youth, to explore the effectiveness of interventions that used school personnel compared to those that used study personnel as CBI implementers, and to determine the effectiveness of CBIs delivered universally compared to those that are delivered in small group settings. 

We identified 25 articles meeting our inclusion criteria and found a mean effect size (ES) of -0.14, (SD=0.48) and a mean weighted ES score of -0.23. 

Results showed that the universal intervention delivery method had a significant influence on the magnitude of the effect size (F(1, 61)=4.84, p=.032). In light of these results we discuss study limitations and suggest future research on potential CBI moderators and the role of CBI in the current school environment. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - David Barnes, Tia N.: tiab@ufl.edu Barnes, Tia N.: School of Special Education, University of Florida, 1403 Norman Hall, PO Box 117050, Gainesville, FL, US, 32611, tiab@ufl.edu Barnes, Tia N.: School of Special Education, University of Florida, Gainesville, FL, US Smith, Stephen W.: School of Human Development and Organizational Studies in Education, University of Florida, Gainesville, FL, US Miller, M. David: School of Special Education, University of Florida, Gainesville, FL, US
AN  - 2014-32546-003
AU  - Barnes,
AU  - T.
AU  - N.
AU  - Smith,
AU  - S.
AU  - Miller,
AU  - M.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.avb.2014.04.013
DP  - Ovid Technologies
KW  - cognitive behavioral interventions, aggression treatment, school environment *Aggressive Behavior *Cognitive Behavior Therapy *Criminal Behavior *School Based Intervention School Environment Behavior Disorders &amp; Antisocial Behavior [3230] Educational/Vo
LA  - English
M3  - Meta Analysis
PY  - 2014
SP  - 311-321
T2  - Aggression and Violent Behavior
TI  - School-based cognitive-behavioral interventions in the treatment of aggression in the United States: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2014-32546-003 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.avb.2014.04.013&amp;issn=1359-1789&amp;isbn=&amp;volume=19&amp;issue=4&amp;spage=311&amp;pages=311-321&amp;date=2014&amp;title=Aggression+and+Violent+Behavior&amp;atitle=School-based+cognitive-behavioral+interventions+in+the+treatment+of+aggression+in+the+United+States%3A+A+meta-analysis.&amp;aulast=Barnes&amp;pid=%3Cauthor%3EBarnes%2C+Tia+N%3C%2Fauthor%3E%3CAN%3E2014-32546-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1359178914000391/1-s2.0-S1359178914000391-main.pdf?_tid=d99b3616-167d-11e5-9ab8-00000aacb35f&amp;acdnat=1434716728_a470300cef4273c02cf8026c2f5abf05
VL  - 19
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder (ADHD) is the most common neurobehavioral disorder of childhood. There is an increasing need to find objective measures and markers of the disorder in order to assess the efficacy of the therapy and to improve follow-up strategies. Actigraphy is an objective method for recording motor activity and sleep parameters using small, computerized, watch-like devices worn on the body, and it has been used in many clinical trials to assess methylphenidate efficacy and adverse effects in ADHD. 

Our article aim is to systematically review and perform a meta-analysis of the current evidence on the role of actigraphy in both the detection of changes in activity and in sleep patterns in randomized clinical trials that compared methylphenidate against placebo in the treatment of ADHD. A comprehensive literature search of PubMed/MEDLINE, Scopus, Embase, Cochrane Library, CINHAL and PsycINFO databases was carried out to find randomized clinical trials comparing methylphenidate versus placebo in children with ADHD, using actigraphic measures as an outcome. No start date limit was used and the search was updated until June 2013. The primary outcome measures were &#039;total sleep time&#039; and daytime &#039;activity mean&#039;. As secondary outcomes, we analyzed &#039;sleep onset latency&#039;, &#039;sleep efficiency&#039; and &#039;wake after sleep onset&#039;. 

Eight articles comprising 393 patients were included in the analysis. Children with ADHD using MPH compared to placebo have a significant difference of a large effect with a diminishing value in the activity mean. For the total sleep time, we found a significant and large effect in the decrease in sleep in MPH group. This study shows that MPH may effectively reduce mean activity in ADHD children, but it may negatively affect total sleep time. &copy; 2013 Springer-Verlag Wien.
AN  - 372493957
AU  - De
AU  - Crescenzo,
AU  - F.
AU  - Armando,
AU  - M.
AU  - Mazzone,
AU  - L.
AU  - Ciliberto,
AU  - M.
AU  - Sciannamea,
AU  - M.
AU  - Figueroa,
AU  - C.
AU  - Janiri,
AU  - L.
AU  - Quested,
AU  - D.
AU  - Vicari,
AU  - S.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1007/s12402-013-0122-x
L1  - internal-pdf://3304356815/De Crescenzo-2014-The use of actigraphy in the.pdf
PY  - 2014
SP  - 49-58
T2  - ADHD Attention Deficit and Hyperactivity Disorders
TI  - The use of actigraphy in the monitoring of methylphenidate versus placebo in ADHD: A meta-analysis
UR  - http://www.springer.com/springerwiennewyork/medicine/journal/12402
UR  - https://link.springer.com/content/pdf/10.1007/s12402-013-0122-x.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Access to qualified cognitive-behavioral therapy (CBT) remains a major barrier to improving clinical outcomes in anxiety disorders. The current meta-analysis examined the efficacy of computerized CBT (cCBT) for anxiety disorders and the durability of treatment gains during follow-up. 

**DATA SOURCES: **
We searched PubMed and references from included trials and previous meta-analyses in the area. 

**STUDY SELECTION: **
We included randomized controlled trials assessing the efficacy of cCBT for non-OCD and non-PTSD anxiety disorders. 

**DATA EXTRACTION: **
Forty trials involving 2,648 participants were included in this meta-analysis. We used a fixed-effect model to examine standardized mean difference in posttreatment anxiety levels. cCBT was compared to wait-list, in-person CBT, and Internet control. We also examined moderators of cCBT treatment gains over follow-up. 

**RESULTS: **
Meta-analysis indicated that cCBT was significantly more effective than wait-list control in the treatment of anxiety disorders (standardized mean difference [SMD] = 0.92 [95% CI, 0.83 to 1.02], k = 31, z = 18.8, P &lt; .001). Moderator analyses also found that cCBT targeting specific anxiety disorders had greater efficacy than that targeting mixed anxiety symptoms. The efficacy of cCBT was equivalent to in-person CBT in studies that compared them head-to-head, for both children and adults (SMD = 0.05 [95% CI, -0.09 to 0.19], k = 15, z = 0.7, P = .46). Longitudinal studies indicate that individuals undergoing cCBT tended to continue to improve after completion of treatment, with longer follow-up periods associated with greater symptom reduction. 

**CONCLUSIONS: **
cCBT represents an efficacious intervention for the treatment of anxiety disorders and may circumvent barriers to accessing traditional CBT treatments. Further research is needed to examine the effectiveness of cCBT in real-world settings, for individuals with clinical comorbidities, and in comparison with more ecologically valid comparison conditions.

&copy; Copyright 2014 Physicians Postgraduate Press, Inc.
AD  - Bloch,Michael H. Child Study Center, Yale University School of Medicine, PO Box 2070900, New Haven, CT 06520 michael.bloch@yale.edu.
AN  - 25093485
AU  - Adelman,
AU  - C.
AU  - B.
AU  - Panza,
AU  - K.
AU  - E.
AU  - Bartley,
AU  - C.
AU  - A.
AU  - Bontempo,
AU  - A.
AU  - Bloch,
AU  - M.
AU  - H.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.4088/JCP.13r08894
DP  - Ovid Technologies
J2  - J Clin Psychiatry
KW  - *Anxiety Disorders/th [Therapy] Cognitive Therapy/is [Instrumentation] *Cognitive Therapy/mt [Methods] *Diagnostic and Statistical Manual of Mental Disorders Humans *User-Computer Interface
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov&#039;t
N1  - Adelman, Caroline B Panza, Kaitlyn E Bartley, Christine A Bontempo, Allyson Bloch, Michael H 1K23MH091240 (United States NIMH NIH HHS) UL1 RR024139 (United States NCRR NIH HHS)
PY  - 2014
SP  - e695-704
T2  - Journal of Clinical Psychiatry
TI  - A meta-analysis of computerized cognitive-behavioral therapy for the treatment of DSM-5 anxiety disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25093485 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25093485&amp;id=doi:10.4088%2FJCP.13r08894&amp;issn=0160-6689&amp;isbn=&amp;volume=75&amp;issue=7&amp;spage=e695&amp;pages=e695-704&amp;date=2014&amp;title=Journal+of+Clinical+Psychiatry&amp;atitle=A+meta-analysis+of+computerized+cognitive-behavioral+therapy+for+the+treatment+of+DSM-5+anxiety+disorders.&amp;aulast=Adelman&amp;pid=%3Cauthor%3EAdelman+CB%3C%2Fauthor%3E%3CAN%3E25093485%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.psychiatrist.com/JCP/article/Pages/2014/v75n07/v75n0704.aspx
UR  - http://www.psychiatrist.com/jcp/article/pages/2014/v75n07/v75n0704.aspx
VL  - 75
ER  -
TY  - JOUR
AB  - Although many post-disaster interventions for children and adolescent survivors of disaster and terrorism have been created, little is known about the effectiveness of such interventions. 

Therefore, this meta-analysis assessed PTSD outcomes among children and adolescent survivors of natural and man-made disasters receiving psychological interventions. Aggregating results from 24 studies (total N = 2630) indicates that children and adolescents receiving psychological intervention fared significantly better than those in control or waitlist groups with respect to PTSD symptoms. 

Moderator effects were also observed for intervention package, treatment modality (group vs. individual), providers&#039; level of training, intervention setting, parental involvement, participant age, length of treatment, intervention delivery timing, and methodological rigor. 

Findings are discussed in detail with suggestions for practice and future research. 

Copyright &copy; 2014, Springer Science+Business Media New York.
AD  - (Newman, Kirlic, Tett, Nelson, Liles) The University of Tulsa Institute of Trauma, Adversity, and Injustice, Department of Psychology, 800 South Tucker Drive, Tulsa, OK 74103, United States (Pfefferbaum) Department of Psychiatry and Behavioral Sciences, College of Medicine, Terrorism and Disaster Center, University of Oklahoma Health Sciences Center, PO Box 26901, Williams Pavilion 3470, Oklahoma City, OK 73126-0901, United States E. Newman, The University of Tulsa Institute of Trauma, Adversity, and Injustice, Department of Psychology, 800 South Tucker Drive, Tulsa, OK 74103, United States
AN  - 53275486
AU  - Newman,
AU  - E.
AU  - Pfefferbaum,
AU  - B.
AU  - Kirlic,
AU  - N.
AU  - Tett,
AU  - R.
AU  - Nelson,
AU  - S.
AU  - Liles,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s11920-014-0462-z
DP  - Ovid Technologies
KW  - Acute stress disorder
KW  - Child disaster
KW  - Interventions
KW  - Meta-analysis
KW  - Natural disaster
KW  - Posttraumatic stress disorder
KW  - Psychosocial treatment
KW  - Terrorism
KW  - Treatment efficacy
KW  - adolescent
KW  - child
KW  - human
KW  - male
KW  - meta analysis
KW  - survivor
KW  - therapy
KW  - treatment duration
L1  - internal-pdf://0441226595/nihms678926.pdf
LA  - English
M3  - Review
N1  - Using Smart Source Parsing ( (no pagination), Date of Publication: 01 Sep 2014
PY  - 2014
T2  - Current Psychiatry Reports
TI  - Meta-Analytic Review of Psychological Interventions for Children Survivors of Natural and Man-Made Disasters
UR  - http://www.springerlink.com/content/1523-3812/http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=53275486http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1007%2Fs11920-014-0462-z&amp;issn=1523-3812&amp;isbn=&amp;volume=16&amp;issue=9&amp;spage=no+pagination&amp;pages=no+pagination&amp;date=2014&amp;title=Current+Psychiatry+Reports&amp;atitle=Meta-Analytic+Review+of+Psychological+Interventions+for+Children+Survivors+of+Natural+and+Man-Made+Disasters&amp;aulast=Newman&amp;pid=%3Cauthor%3ENewman+E.%3C%2Fauthor%3E%3CAN%3E53275486%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3E
VL  - 16
ER  -
TY  - JOUR
AB  - The aim of this systematic review was to determine the efficacy of parenting interventions for parents of preterm infants to improve child behavior. 

Randomized controlled trials (RCTs) of parenting interventions for parents of preterm infants were included. 
Searchers were conducted of PubMed from 1951 to April 2013, the Cumulative Index to Nursing and Allied Health Literature (CINAHL) from 1982 to April 2013, Scopus from 1966 to April 2013, PsycINFO from 1840 to April 2013, the Web of Science, and the Cochrane Library. 

Twelve RCTs were identified that assessed child behavior. Of these studies, only data from three were able to be pooled for meta-analysis: the Infant Health and Development Program (IHDP) at 3 years, the Mother-Infant Transaction Program (modified; MITP-M) at 5 years, and the Victorian Infant Brain Studies (VIBeS Plus) at 4 years. 

Outcome from this analysis revealed a small, but significant, effect on child behavior favoring the intervention (95% CI: 0.08-0.32; p = .001). 

There is evidence that preterm parenting interventions can improve child behavior. Streamlined interventions such as MITP-M and VIBeS Plus that have a strong focus on the mother-infant relationship may have greatest potential.
AD  - [Herd, Michael; Whittingham, Koa; Sanders, Matthew; Boyd, Roslyn N.] Univ Queensland, Brisbane, Qld, Australia. [Colditz, Paul] Univ Queensland, Royal Brisbane &amp; Womens Hosp, Clin Res Ctr, Brisbane, Qld, Australia. Herd, M (reprint author), Royal Brisbane &amp; Womens Hosp, Perinatal Res Ctr, Level 6 Ned Hanlon Bldg, Herston, Qld, Australia. michael.herd@uqconnect.edu.au
AN  - WOS:000345294500011
AU  - Herd,
AU  - M.
AU  - Whittingham,
AU  - K.
AU  - Sanders,
AU  - M.
AU  - Colditz,
AU  - P.
AU  - Boyd,
AU  - R.
AU  - N.
DA  - Nov-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/imhj.21480
J2  - Infant Ment. Health J.
KW  - LOW-BIRTH-WEIGHT RANDOMIZED CONTROLLED-TRIAL PREMATURE-INFANTS DEVELOPMENT-PROGRAM 3-YEAR-OLD CHILDREN EMOTIONAL-PROBLEMS PRESCHOOL-AGE OUTCOMES HEALTH BORN Psychology, Developmental
L1  - internal-pdf://4032998378/Herd-2014-EFFICACY OF PREVENTATIVE PARENTING I.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AU0DT Times Cited: 0 Cited Reference Count: 54 Herd, Michael Whittingham, Koa Sanders, Matthew Colditz, Paul Boyd, Roslyn N. Boyd, Roslyn/A-4498-2011 Boyd, Roslyn/0000-0002-4919-5975 WILEY-BLACKWELL HOBOKEN INFANT MENT HEALTH J
PY  - 2014
SP  - 630-641
T2  - Infant Mental Health Journal
TI  - Efficacy of preventative parenting interventions for parents of preterm infants on later child behavior: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000345294500011http://onlinelibrary.wiley.com/store/10.1002/imhj.21480/asset/imhj21480.pdf?v=1&amp;t=ib3j3zyn&amp;s=66ea53d46d759199421ee786a7f187d75a9e61b4
UR  - http://onlinelibrary.wiley.com/store/10.1002/imhj.21480/asset/imhj21480.pdf?v=1&amp;t=j8yetp4y&amp;s=f3c5e20e415f4633badf59298b710268d07f2a7e
VL  - 35
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To assess the long-term safety of drugs for attention deficit hyperactivity disorder (ADHD). 

**METHODS: **
A bibliographic search was performed in the MEDLINE, EMBASE and PsycINFO databases for prospective studies evaluating the incidence of adverse events (AEs) in children and adolescents treated for ADHD. 

**RESULTS: **
A total of six prospective studies that monitored drug safety during therapy for at least 12 weeks were retrieved. The drugs studied were atomoxetine (two studies, 802 patients), osmotic-controlled released oral methylphenidate formulation (two studies, 512 patients), extended release formulation of mixed amphetamine salts (one study, 568 patients) and transdermal methylphenidate (one study, 326 patients). Heterogeneity was found in the duration of follow-up (ranging between 1 and 4 years) and in the way data were reported. The rate of treatment-related AEs ranged from 58% to 78%, and the rate of discontinuation due to AEs ranged from 8% to 25% of the children. Decreased appetite, insomnia, headache and abdominal pain were the most common AEs observed. Most AEs and cases of discontinuation occurred during the first few months of treatment. 

**CONCLUSIONS: **
Few studies evaluated the long-term safety of drugs for ADHD. Heterogeneity in follow-up duration and in data reporting made comparing different studies and drugs difficult. A systematic monitoring of long-term safety is needed.

Copyright Published by the BMJ Publishing Group Limited.
AD  - Clavenna,Antonio. Laboratory for Mother and Child Health, Department of Public Health, IRCCS-Istituto di Ricerche Farmacologiche &quot;Mario Negri&quot;, Milan, Italy. Bonati,Maurizio. Laboratory for Mother and Child Health, Department of Public Health, IRCCS-Istituto di Ricerche Farmacologiche &quot;Mario Negri&quot;, Milan, Italy.
AN  - 24748641
AU  - Clavenna,
AU  - A.
AU  - Bonati,
AU  - M.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/cch.12179
DP  - Ovid Technologies
J2  - Arch Dis Child
KW  - Adolescent Amphetamines/ae [Adverse Effects] Amphetamines/tu [Therapeutic Use] *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] Central Nervous System Stimulants/ad [Administration &amp; Dosage] Central Nervous System Stimulants/ae [Adverse
L1  - internal-pdf://2061874634/Clavenna-2014-Safety of medicines used for ADH.pdf
LA  - English
M3  - Review
N1  - Clavenna, Antonio Bonati, Maurizio
PY  - 2014
SP  - 866-72
T2  - Archives of Disease in Childhood
TI  - Safety of medicines used for ADHD in children: a review of published prospective clinical trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24748641
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24748641&amp;id=doi:10.1136%2Farchdischild-2013-304170&amp;issn=0003-9888&amp;isbn=&amp;volume=99&amp;issue=9&amp;spage=866&amp;pages=866-72&amp;date=2014&amp;title=Archives+of+Disease+in+Childhood&amp;atitle=Safety+of+medicines+used+for+ADHD+in+children%3A+a+review+of+published+prospective+clinical+trials.&amp;aulast=Clavenna&amp;pid=%3Cauthor%3EClavenna+A%3C%2Fauthor%3E%3CAN%3E24748641%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://adc.bmj.com/content/99/9/866.full.pdf
UR  - http://adc.bmj.com/content/archdischild/99/9/866.full.pdf
VL  - 99
ER  -
TY  - JOUR
AB  - Natural disasters can have devastating consequences. Each year, about 225 million people are victims of natural disasters worldwide, and up to 13,5 million of these people can develop post-traumatic stress disorder (PTSD) in the first or second year following the disaster. 

Cognitive-behavior therapy (CBT) is the first-choice treatment for this disorder. In order to evaluate the efficacy of psychotherapeutic treatment based on cognitive-behavior therapy for people who developed post traumatic stress disorder after natural disasters we conducted a systematic search of published studies. 

We used the terms reported below in the electronic databases ISI Web of Science, PsycINFO, PubMed, PILOTS and Scopus with no restrictions of language or publication date. Articles that described randomized controlled, non-randomized controlled and non controlled studies on the efficacy of cognitive-behavior therapy for individuals diagnosed with post-traumatic stress disorder after exposure to a natural disaster were eligible for inclusion. 

The studies were required to use a standardized measure of effectiveness before and after the intervention and have a group of patients who had used cognitive-behavior therapy as the only intervention. Our search identified 820 studies, and 11 were selected for this review. 

These 11 studies involved 742 subjects, 10 related to earthquakes and 1 to a hurricane. The cognitive-behavior therapy techniques used were various: 7 studies used exposure therapy, 2 studies used problem solving, and the only 2 studies with adolescents used techniques including reconstructions and reprocessing of the traumatic experience. 

As limitations, the search involved only five electronic databases, no experts in the field were consulted, and the heterogeneity of the findings made it impossible to perform a meta-analysis. The results suggest the efficacy of cognitive-behavior therapy, particularly exposure techniques, for the treatment of post-traumatic stress disorder after earthquakes. However, further studies with stronger methodologies, i.e. randomized-control trials and non-randomized controlled trials, are needed.
AD  - Lopes, Alessandra Pereira. Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; D&#039;Or Institute for Research and Education, Rio de Janeiro, Brazil.Macedo, Tania Fagundes. Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.Coutinho, Evandro Silva Freire. Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Department of Epidemiology, Escola Nacional de Saude Publica, Rio de Janeiro, Brazil.Figueira, Ivan. Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.Ventura, Paula Rui. Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Psychological Institute, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
AN  - 25296020
AU  - Lopes,
AU  - A.
AU  - P.
AU  - Macedo,
AU  - T.
AU  - F.
AU  - Coutinho,
AU  - E.
AU  - S.
AU  - Figueira,
AU  - I.
AU  - Ventura,
AU  - P.
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0109013
DP  - Ovid Technologies
J2  - PLoS ONE
KW  - Clinical Trials as Topic
KW  - *Cognitive Therapy/mt [Methods]
KW  - Humans
KW  - *Stress Disorders, Post-Traumatic/th [Therapy]
L1  - internal-pdf://1399458809/Lopes-2014-Systematic review of the efficacy o.pdf
LA  - English
M3  - Review
N1  - Lopes, Alessandra PereiraMacedo, Tania FagundesCoutinho, Evandro Silva FreireFigueira, IvanVentura, Paula Rui
PY  - 2014
SP  - e109013
T2  - PLoS ONE [Electronic Resource]
TI  - Systematic review of the efficacy of cognitive-behavior therapy related treatments for victims of natural disasters: a worldwide problem
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=25296020
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25296020&amp;id=doi:10.1371%2Fjournal.pone.0109013&amp;issn=1932-6203&amp;isbn=&amp;volume=9&amp;issue=10&amp;spage=e109013&amp;pages=e109013&amp;date=2014&amp;title=PLoS+ONE+%5BElectronic+Resource%5D&amp;atitle=Systematic+review+of+the+efficacy+of+cognitive-behavior+therapy+related+treatments+for+victims+of+natural+disasters%3A+a+worldwide+problem.&amp;aulast=Lopes&amp;pid=%3Cauthor%3ELopes+AP%3C%2Fauthor%3E%3CAN%3E25296020%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189911/pdf/pone.0109013.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
New generation antidepressant therapies, including serotonin-norepinephrine reuptake inhibitor (SNRIs) and selective serotonin reuptake inhibitors (SSRIs) were introduced in the late 1980s; however, few comprehensive studies compared the benefits and risks of various contemporary treatments for major depressive disorder (MDD) in pediatric patients. 

**OBJECTIVE: **
Multiple-treatments meta-analysis (MTM) was conducted to assess efficacy, acceptability, and safety of contemporary interventions in children and adolescents with MDD. 

**METHODS: **
Cochrane Library, AMED, CINAHL, EMBASE, LiLACS, MEDLINE, PSYCINFO, PSYNDEX, and Journal of Medicine and Pharmacy databases were searched for randomized controlled trials (RCTs) comparing medicinal interventions (citalopram, escitalopram, fluoxetine, mirtazapine, paroxetine, sertraline, venlafaxine), cognitive behavioral therapy (CBT), combined fluoxetine with CBT, and placebo treatment for acute MDD from January 1988 to March 2013. Treatment success, dropout rate, and suicidal ideation/attempt outcomes were measured. Bayesian methods were used to conduct a MTM including age and funding subgroups. 

**RESULTS: **
A total of 21 RCTs (4969 participants) were identified. Combined fluoxetine/CBT exhibited the highest efficacy, with fluoxetine alone superior to CBT, paroxetine, sertraline, citalopram, escitalopram, and placebo treatment. Sertraline, paroxetine, escitalopram, and venlafaxine showed superior acceptability to fluoxetine and combined fluoxetine/CBT. Combined fluoxetine/CBT combination was less safe, though CBT was safer than fluoxetine alone. Combined fluoxetine/CBT, fluoxetine, and mirtazapine exhibited the highest efficacy; sertraline, escitalopram, venlafaxine, and paroxetine were the best tolerated; and mirtazapine and venlafaxine were the safest. 

**CONCLUSIONS: **
Sertraline and mirtazapine exhibited optimally balanced efficacy, acceptability, and safety for first-line acute treatment of child and adolescent MDD.
AD  - Ma,Dongfeng. Affiliated ZhongDa Hospital and the Institution Neuropsychiatry of Southeast University , Nanjing , China.
AN  - 24188102
AU  - Ma,
AU  - D.
AU  - Zhang,
AU  - Z.
AU  - Zhang,
AU  - X.
AU  - Li,
AU  - L.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1185/03007995.2013.860020
DP  - Ovid Technologies
J2  - Curr Med Res Opin
LA  - English
N1  - Ma, Dongfeng Zhang, Zhijun Zhang, Xiangrong Li, Lingjiang
PY  - 2014
SP  - 971-95
T2  - Current Medical Research &amp; Opinion
TI  - Comparative efficacy, acceptability, and safety of medicinal, cognitive-behavioral therapy, and placebo treatments for acute major depressive disorder in children and adolescents: a multiple-treatments meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24188102 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24188102&amp;id=doi:10.1185%2F03007995.2013.860020&amp;issn=0300-7995&amp;isbn=&amp;volume=30&amp;issue=6&amp;spage=971&amp;pages=971-95&amp;date=2014&amp;title=Current+Medical+Research+%26+Opinion&amp;atitle=Comparative+efficacy%2C+acceptability%2C+and+safety+of+medicinal%2C+cognitive-behavioral+therapy%2C+and+placebo+treatments+for+acute+major+depressive+disorder+in+children+and+adolescents%3A+a+multiple-treatments+meta-analysis.&amp;aulast=Ma&amp;pid=%3Cauthor%3EMa+D%3C%2Fauthor%3E%3CAN%3E24188102%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://informahealthcare.com/doi/pdfplus/10.1185/03007995.2013.860020
VL  - 30
ER  -
TY  - JOUR
AB  - Pediatric obsessive-compulsive disorder (OCD) is a chronic and impairing condition that often persists into adulthood. Barrett, Farrell, Pina, Peris, and Piacentini (2008), in this journal, provided a detailed review of evidence-based psychosocial treatments for youth with OCD. 

The current review provides an evidence base update of the pediatric OCD psychosocial treatment literature with particular attention to advances in the field as well as to the methodological challenges inherent in evaluating such findings. Psychosocial treatment studies conducted since the last review are described and evaluated according to methodological rigor and evidence-based classification using the JCCAP evidence-based treatment evaluation criteria (Southam-Gerow &amp; Prinstein, this issue). 

Findings from this review clearly converge in support of cognitive-behavioral therapy as an effective and appropriate first line treatment for youth with OCD (either alone or in combination with medication). Although no treatment for pediatric OCD has yet to be designated as &quot;well-established,&quot; both individual and individual family-based treatments have been shown to be &quot;probably efficacious.&quot; 

Moderators and predictors of treatment outcome are discussed as are the areas where we have advanced the field and the areas where we have room to grow. The methodological and clinical challenges inherent in a review of the evidence base are reviewed. Finally, future research directions are outlined.
AD  - Freeman,Jennifer. a Alpert Medical School of Brown University, Bradley/Hasbro Children&#039;s Research Center.
AN  - 23746138
AU  - Freeman,
AU  - J.
AU  - Garcia,
AU  - A.
AU  - Frank,
AU  - H.
AU  - Benito,
AU  - K.
AU  - Conelea,
AU  - C.
AU  - Walther,
AU  - M.
AU  - Edmunds,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/15374416.2013.804386.
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
KW  - Adolescent Child Cognitive Therapy *Evidence-Based Medicine Humans *Obsessive-Compulsive Disorder/th [Therapy] *Psychotherapy Treatment Outcome
LA  - English
M3  - Review
N1  - Freeman, Jennifer Garcia, Abbe Frank, Hannah Benito, Kristen Conelea, Christine Walther, Michael Edmunds, Julie F32 MH095274 (United States NIMH NIH HHS)
PY  - 2014
SP  - 7-26
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Evidence base update for psychosocial treatments for pediatric obsessive-compulsive disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23746138
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23746138&amp;id=doi:10.1080%2F15374416.2013.804386&amp;issn=1537-4416&amp;isbn=&amp;volume=43&amp;issue=1&amp;spage=7&amp;pages=7-26&amp;date=2014&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Evidence+base+update+for+psychosocial+treatments+for+pediatric+obsessive-compulsive+disorder.&amp;aulast=Freeman&amp;pid=%3Cauthor%3EFreeman+J%3C%2Fauthor%3E%3CAN%3E23746138%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/15374416.2013.804386
VL  - 43
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Meta-analytic studies have not confirmed that involving parents in cognitive behavior therapy (CBT) for anxious children is therapeutically beneficial. There is also great heterogeneity in the type of parental involvement included. We investigated parental involvement focused on contingency management (CM) and transfer of control (TC) as a potential outcome moderator using a meta-analysis with individual patient data. 

**METHOD: **
Investigators of randomized controlled trials (RCTs) of CBT for anxious children, identified systematically, were invited to submit their data. Conditions in each RCT were coded based on type of parental involvement in CBT (i.e., low involvement, active involvement without emphasis on CM or TC, active involvement with emphasis on CM or TC). Treatment outcomes were compared using a 1-stage meta-analysis. 

**RESULTS: **
All cases involved in active treatment (894 of 1,618) were included for subgroup analyses. Across all CBT groups, means of clinical severity, anxiety, and internalizing symptoms significantly decreased posttreatment and were comparable across groups. The group without emphasis on CM or TC showed a higher proportion with posttreatment anxiety diagnoses than the low-involvement group. Between posttreatment and 1-year follow-up, the proportion with anxiety diagnoses significantly decreased in CBT with active parental involvement with emphasis on CM or TC, whereas treatment gains were merely maintained in the other 2 groups. 

**CONCLUSIONS: **
CBT for anxious children is an effective treatment with or without active parental involvement. However, CBT with active parental involvement emphasizing CM or TC may support long-term maintenance of treatment gains. RESULTS should be replicated as additional RCTs are published.
AD  - Manassis,Katharina. Department of Psychiatry. Lee,Trevor Changgun. Faculty of Medicine, University of Toronto. Bennett,Kathryn. McMaster University. Zhao,Xiu Yan. Biostatistics, Design, and Analysis Unit, Hospital for Sick Children. Mendlowitz,Sandra. Department of Psychiatry, Hospital for Sick Children. Duda,Stephanie. Clinical Epidemiology and Biostatistics, McMaster University. Saini,Michael. Faculty of Social Work, University of Toronto. Wilansky,Pamela. Department of Psychiatry, University of Toronto. Baer,Susan. Department of Psychiatry, University of British Columbia. Barrett,Paula. Pathways Health and Research Centre, West End. Bodden,Denise. University of Utrecht. Cobham,Vanessa E. School of Psychology, University of Queensland. Dadds,Mark R. School of Psychology, University of New South Wales. Flannery-Schroeder,Ellen. University of Rhode Island. Ginsburg,Golda. Johns Hopkins University School of Medicine. Heyne,David. Leiden University. Hudson,Jennifer L. Department of Psychology, Macquarie University. Kendall,Philip C. Department of Psychology, Temple University. Liber,Juliette. Leiden University. Masia-Warner,Carrie. Department of Psychology, William Paterson University. Nauta,Maaike H. University of Groningen. Rapee,Ronald M. Department of Psychology, Macquarie University. Silverman,Wendy. Department of Psychiatry, Yale University. Siqueland,Lynne. Children&#039;s Center for OCD and Anxiety. Spence,Susan H. Griffith University. Utens,Elisabeth. Erasmus Medical Center Sophia-Children&#039;s Hospital. Wood,Jeffrey J. Department of Psychiatry, University of California.
AN  - 24841867
AU  - Manassis,
AU  - K.
AU  - Lee,
AU  - T.
AU  - C.
AU  - Bennett,
AU  - K.
AU  - Zhao,
AU  - X.
AU  - Y.
AU  - Mendlowitz,
AU  - S.
AU  - Duda,
AU  - S.
AU  - Saini,
AU  - M.
AU  - Wilansky,
AU  - P.
AU  - Baer,
AU  - S.
AU  - Barrett,
AU  - P.
AU  - Bodden,
AU  - D.
AU  - Cobham,
AU  - V.
AU  - E.
AU  - Dadds,
AU  - M.
AU  - R.
AU  - Flannery-Schroeder,
AU  - E.
AU  - Ginsburg,
AU  - G.
AU  - Heyne,
AU  - D.
AU  - Hudson,
AU  - J.
AU  - L.
AU  - Kendall,
AU  - P.
AU  - C.
AU  - Liber,
AU  - J.
AU  - Masia-Warner,
AU  - C.
AU  - Nauta,
AU  - M.
AU  - H.
AU  - Rapee,
AU  - R.
AU  - M.
AU  - Silverman,
AU  - W.
AU  - Siqueland,
AU  - L.
AU  - Spence,
AU  - S.
AU  - H.
AU  - Utens,
AU  - E.
AU  - Wood,
AU  - J.
AU  - J.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1037/a0036969
DP  - Ovid Technologies
J2  - J Consult Clin Psychol
LA  - English
N1  - Manassis, Katharina Lee, Trevor Changgun Bennett, Kathryn Zhao, Xiu Yan Mendlowitz, Sandra Duda, Stephanie Saini, Michael Wilansky, Pamela Baer, Susan Barrett, Paula Bodden, Denise Cobham, Vanessa E Dadds, Mark R Flannery-Schroeder, Ellen Ginsburg, Golda Heyne, David Hudson, Jennifer L Kendall, Philip C Liber, Juliette Masia-Warner, Carrie Nauta, Maaike H Rapee, Ronald M Silverman, Wendy Siqueland, Lynne Spence, Susan H Utens, Elisabeth Wood, Jeffrey J
PY  - 2014
SP  - 1163-72
T2  - Journal of Consulting &amp; Clinical Psychology
TI  - Types of parental involvement in CBT with anxious youth: a preliminary meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24841867
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24841867&amp;id=doi:10.1037%2Fa0036969&amp;issn=0022-006X&amp;isbn=&amp;volume=82&amp;issue=6&amp;spage=1163&amp;pages=1163-72&amp;date=2014&amp;title=Journal+of+Consulting+%26+Clinical+Psychology&amp;atitle=Types+of+parental+involvement+in+CBT+with+anxious+youth%3A+a+preliminary+meta-analysis.&amp;aulast=Manassis&amp;pid=%3Cauthor%3EManassis+K%3C%2Fauthor%3E%3CAN%3E24841867%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://psycnet.apa.org/journals/ccp/82/6/1163.pdf
VL  - 82
ER  -
TY  - JOUR
AB  - **OBJECTIVE:**
To review the current literature on the efficacy and safety of serotonin norepinephrine reuptake inhibitors in the treatment of attention-deficit hyperactivity disorder (ADHD) in the pediatric population. 

**DATA SOURCES: **
A literature search from 1996 to August 2013 was conducted using MEDLINE, CINAHL, and EMBASE databases. Search terms included attention-deficit hyperactivity disorder, serotonin norepinephrine reuptake inhibitor, pediatric attention-deficit hyperactivity disorder, venlafaxine, duloxetine, desvenlafaxine, milnacipran, and nefazodone. 

**STUDY SELECTION AND DATA EXTRACTION: **
Relevant articles on duloxetine and venlafaxine for the treatment of pediatric ADHD were reviewed; 5 studies on venlafaxine and 1 study on duloxetine were evaluated. Studies included open-label and randomized, double-blind trials. Case studies in pediatric populations and all studies in adult populations were excluded. 

**DATA SYNTHESIS: **
Patients 6 to 17 years old were evaluated in the venlafaxine and duloxetine studies. Trials on venlafaxine, ranging from 2 to 6 weeks, showed patient improvement as measured by the Conners Rating Scale and ADHD Rating Scale. Venlafaxine was initiated at 12.5 to 25 mg/d and titrated up to 1.4 to 3.8 mg/kg/d to a maximum of 150 mg/d. Duloxetine showed minimal efficacy in treating ADHD symptoms at doses of 60 mg/d at 6 weeks. The most common side effects for venlafaxine and duloxetine included drowsiness and decreased appetite, respectively. 

**CONCLUSIONS:**
Data for venlafaxine and duloxetine are limited. However, venlafaxine may be considered as an alternative agent when patients cannot tolerate or fail stimulants, tricyclic antidepressants, or bupropion. Duloxetine has been studied in children; however, with only 1 study available, it is difficult to recommend.
AD  - Park,Pauline. VA Connecticut Healthcare, West Haven, CT, USA.
AN  - 24259607
AU  - Park,
AU  - P.
AU  - Caballero,
AU  - J.
AU  - Omidian,
AU  - H.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1060028013506561
DP  - Ovid Technologies
J2  - Ann Pharmacother
KW  - *Adrenergic Uptake Inhibitors/tu [Therapeutic Use] *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] Cyclohexanols/tu [Therapeutic Use] Humans Norepinephrine/me [Metabolism] *Serotonin Uptake Inhibitors/tu [Therapeutic Use] Thiophenes/tu
LA  - English
M3  - Review
N1  - Park, Pauline Caballero, Joshua Omidian, Hossein
PY  - 2014
SP  - 86-92
T2  - Annals of Pharmacotherapy
TI  - Use of serotonin norepinephrine reuptake inhibitors in the treatment of attention-deficit hyperactivity disorder in pediatrics
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24259607
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24259607&amp;id=doi:10.1177%2F1060028013506561&amp;issn=1060-0280&amp;isbn=&amp;volume=48&amp;issue=1&amp;spage=86&amp;pages=86-92&amp;date=2014&amp;title=Annals+of+Pharmacotherapy&amp;atitle=Use+of+serotonin+norepinephrine+reuptake+inhibitors+in+the+treatment+of+attention-deficit+hyperactivity+disorder+in+pediatrics.&amp;aulast=Park&amp;pid=%3Cauthor%3EPark+P%3C%2Fauthor%3E%3CAN%3E24259607%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://aop.sagepub.com/content/48/1/86.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/1060028013506561?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 48
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Depression and problematic substance use represent two of the major social and health problems facing young people internationally. Frequently, these conditions co-occur and this co-occurrence is associated with greater functional impact, poorer treatment outcomes, and increased costs to both society and the individual. 

**OBJECTIVE:** 
This review aims to identify peer-reviewed published trials of interventions for co-occurring substance use and depression delivered to young people, describe these interventions, and critique the methodological quality of the studies. 

**METHOD: **
Eleven electronic databases were searched. The reference lists of relevant review papers were searched manually for additional studies not identified by the electronic database search. 

**RESULTS: **
Initially, 1,976 studies were identified, of which 22 were classified as trial studies of youth-based treatment interventions for co-occurring substance use and depression. Ten of these studies met criteria for review. The majority (60%) utilized a pharmacotherapy component, but found it to be generally no better than placebo when both groups received adjunct counselling. METHODological quality of studies varied. 

**CONCLUSIONS: **
There is a dearth of trials of interventions for co-occurring depression and substance use disorders in young people. The limited data available is promising regarding the overall effectiveness of a psychological counselling approach. Given the importance of early intervention, and the difficulties faced when engaging youth in treatment, there is a need for further focused effort amongst this group. This may require more innovative techniques in intervention design and implementation. Recent advances in Internet- and mobile phone-based therapies present a potential avenue for further research.
AD  - Kay-Lambkin,Frances J. National Drug and Alcohol Research Centre, University of New South Wales, NSW, 2052, Australia. m.deady@unsw.edu.au.
AN  - 25323123
AU  - Deady,
AU  - M.
AU  - Teesson,
AU  - M.
AU  - Kay-Lambkin,
AU  - F.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2174/1874473707666141015220608
DP  - Ovid Technologies
J2  - Curr Drug Abuse Rev
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Deady, Mark Teesson, Maree Kay-Lambkin, Frances J
PY  - 2014
SP  - 3-17
T2  - Current Drug Abuse Reviews
TI  - Treatments for co-occurring depression and substance use in young people: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25323123 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25323123&amp;id=doi:&amp;issn=1874-4737&amp;isbn=&amp;volume=7&amp;issue=1&amp;spage=3&amp;pages=3-17&amp;date=2014&amp;title=Current+Drug+Abuse+Reviews&amp;atitle=Treatments+for+co-occurring+depression+and+substance+use+in+young+people%3A+a+systematic+review.&amp;aulast=Deady&amp;pid=%3Cauthor%3EDeady+M%3C%2Fauthor%3E%3CAN%3E25323123%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://www.eurekaselect.com/125404/article
VL  - 7
ER  -
TY  - JOUR
AB  - This article reports the results of a meta-analysis of technology-based intervention studies for children with autism spectrum disorders. 

We conducted a systematic review of research that used a pre-post design to assess innovative technology interventions, including computer programs, virtual reality, and robotics. 

The selected studies provided interventions via a desktop computer, interactive DVD, shared active surface, and virtual reality. None employed robotics. 

The results provide evidence for the overall effectiveness of technology-based training. The overall mean effect size for posttests of controlled studies of children with autism spectrum disorders who received technology-based interventions was significantly different from zero and approached the medium magnitude, d = 0.47 (confidence interval: 0.08-0.86). 

The influence of age and IQ was not significant. Differences in training procedures are discussed in the light of the negative correlation that was found between the intervention durations and the studies&#039; effect sizes. 

The results of this meta-analysis provide support for the continuing development, evaluation, and clinical usage of technology-based intervention for individuals with autism spectrum disorders.
AD  - [Grynszpan, Ouriel] Univ Paris 06, F-75252 Paris 05, France. [Grynszpan, Ouriel; Perez-Diaz, Fernando] CNRS, USR 3246, F-75700 Paris, France. [Weiss, Patrice L. (Tamar); Gal, Eynat] Univ Haifa, IL-31999 Haifa, Israel. Grynszpan, O (reprint author), Hop La Pitie Salpetriere, CNRS, Ctr Emot, USR 3246, Pavillon Clerambault,47 Blvd Hop, F-75013 Paris, France. ouriel.grynszpan@upmc.fr
AN  - WOS:000334377400001
AU  - Grynszpan,
AU  - O.
AU  - Weiss,
AU  - P.
AU  - L.
AU  - Perez-Diaz,
AU  - F.
AU  - Gal,
AU  - E.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1362361313476767
J2  - Autism
KW  - autism spectrum disorders computer innovative technology meta-analysis remediation robotics systematic review training virtual reality COMPUTER-ASSISTED-INSTRUCTION HIGH-FUNCTIONING AUTISM COMPLEX EMOTION RECOGNITION ASPERGER-SYNDROME VIRTUAL-REALITY SO
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AF0BU Times Cited: 2 Cited Reference Count: 97 Grynszpan, Ouriel Weiss, Patrice L. (Tamar) Perez-Diaz, Fernando Gal, Eynat 2 SAGE PUBLICATIONS LTD LONDON AUTISM
PY  - 2014
SP  - 346-361
T2  - Autism
TI  - Innovative technology- based interventions for autism spectrum disorders: A meta- analysis
UR  - &lt;Go to ISI&gt;://WOS:000334377400001http://aut.sagepub.com/content/18/4/346.longhttp://aut.sagepub.com/content/18/4/346.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/1362361313476767?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 18
ER  -
TY  - JOUR
AB  - **Objective: **
To review the basic pharmacology and published literature regarding use of guanfacine extended-release (GXR) for the treatment of attention deficit/hyperactivity disorder in children and adolescents. 

**Methods: **
A literature review was conducted using the search terms: &#039;guanfacine&#039;, with limits set to: Human trials, English Language, and All Child (Age 0-18). Articles pertaining to guanfacine immediate-release or for indications other than attention deficit/hyperactivity disorder (ADHD) were not included for analysis. Additional articles were identified from reference information and poster presentation data. 

**Results: **
Six prospective, randomized controlled trials (RCT) and four open-label trials (including two long-term safety extension trials) were identified for GXR in the treatment of ADHD. All published RCTs showed superiority over placebo on the primary outcome measure. Subgroup analysis of available RCT data showed no efficacy of GXR at any dose in adolescents. Adverse effects in GXR trials were generally mild to moderate. High rates of early discontinuation were observed in long-term open-label extension trials. 

**Conclusion:** 
GXR is an effective option for treatment of ADHD in patients 6-12 years of age as monotherapy, or as adjunctive treatment to psychostimulants. 

&copy; 2013 Shire Canada Inc. All rights reserved.
AD  - (Elbe) Division of Children&#039;s and Women&#039;s Mental Health, BC Mental Health and Addiction Services, Vancouver, BC, Canada (Elbe) Department of Pharmacy, BC Children&#039;s Hospital, Vancouver, BC, Canada (Reddy) The Bellevue Clinic, West Vancouver, BC, Canada D. Elbe, Division of Children&#039;s and Women&#039;s Mental Health, BC Mental Health and Addiction Services, Vancouver, BC, Canada. E-mail: delbe@cw.bc.ca
AN  - 2014094645
AU  - Elbe,
AU  - D.
AU  - Reddy,
AU  - D.
DA  - February
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /pubmed/24516477
DP  - Ovid Technologies
KW  - adhd Adolescent Alpha2-agonist Child Guanfacine abdominal pain/si [Side Effect] ADHD rating scale IV anorexia/si [Side Effect] article atrioventricular block/si [Side Effect] attention deficit disorder/dt [Drug Therapy] bradycardia/si [Side Effect] card
LA  - English
PY  - 2014
SP  - 48-60
T2  - Journal of the Canadian Academy of Child and Adolescent Psychiatry
TI  - Focus on guanfacine extended-release: A review of its use in child and adolescent psychiatry
UR  - http://www.cacap-acpea.org/
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed12&amp;AN=2014094645
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:&amp;issn=1719-8429&amp;isbn=&amp;volume=23&amp;issue=1&amp;spage=48&amp;pages=48-60&amp;date=2014&amp;title=Journal+of+the+Canadian+Academy+of+Child+and+Adolescent+Psychiatry&amp;atitle=Focus+on+guanfacine+extended-release%3A+A+review+of+its+use+in+child+and+adolescent+psychiatry&amp;aulast=Elbe&amp;pid=%3Cauthor%3EElbe+D.%3C%2Fauthor%3E%3CAN%3E2014094645%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917669/pdf/ccap_23_p0048.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - To review the evidence from randomized controlled trials (RCTs) on the safety and efficacy of guanfacine in pediatric attention deficit hyperactivity disorder (ADHD), a bibliographic search up to May 2014 was performed using the Cochrane Library&#039;s Central Register of Controlled Trials, the Embase, PsycINFO, and Medline databases, and clinical trials registers. 

The search terms used were: [&quot;guanfacine&quot;] and [&quot;child&quot; or &quot;adolescent&quot; or &quot;pediatrics&quot;] and [&quot;randomized controlled trial&quot;] and [&quot;Attention Deficit Disorder with Hyperactivity&quot; or &quot;Attention Deficit Disorder&quot; or &quot;Attention Hyperactivity Disorder&quot; or &quot;Hyperactivity&quot; or &quot;ADHD&quot;]. A meta-analysis was performed using response, defined as a score &lt; 2 on the Clinical Global Impression Improvement score, as the outcome measure. In all, 7 out of 48 studies were included, for a total of 1752 participants. 

All studies compared guanfacine versus placebo, with a duration ranging from 6 to 16 weeks. In all, the Clinical Global Impression Improvement score was reported as a secondary measure. Overall, 694/1177 (59.0%) participants in the guanfacine group benefited from the treatment compared to 192/575 (33.3%) in the placebo group (pooled OR 3.2; 95%CI 2.4-4.1). 

The participants with at least one adverse event were 948 (82.4%) in the guanfacine and 376 (67.9%) in the placebo group (OR 2.6; 95%CI 1.6-4.4). Somnolence (OR 4.9), sedation (OR 2.8), and fatigue (OR 2.2), were the adverse events with the greatest risk of occurrence in the guanfacine versus the placebo group. 

On the basis of seven randomized, placebo controlled trials guanfacine resulted safe and effective in treating children and adolescents with ADHD.

Copyright &copy; 2014 Elsevier B.V. and ECNP. All rights reserved.
AD  - Ruggiero,Simona. Center of Pharmacosurveillance and Pharmacoepidemiology, Department of Experimental Medicine, Section of Pharmacology &quot;L. Donatelli&quot;, Faculty of Medicine and Surgery, Second University of Naples, Italy. Clavenna,Antonio. Laboratory for Mother and Child Health, Department of Public Health, IRCCS - Istituto di Ricerche Farmacologiche &quot;Mario Negri&quot;, Milan, Italy. Electronic address: antonio.clavenna@marionegri.it. Reale,Laura. Laboratory for Mother and Child Health, Department of Public Health, IRCCS - Istituto di Ricerche Farmacologiche &quot;Mario Negri&quot;, Milan, Italy. Capuano,Annalisa. Center of Pharmacosurveillance and Pharmacoepidemiology, Department of Experimental Medicine, Section of Pharmacology &quot;L. Donatelli&quot;, Faculty of Medicine and Surgery, Second University of Naples, Italy. Rossi,Francesco. Center of Pharmacosurveillance and Pharmacoepidemiology, Department of Experimental Medicine, Section of Pharmacology &quot;L. Donatelli&quot;, Faculty of Medicine and Surgery, Second University of Naples, Italy. Bonati,Maurizio. Laboratory for Mother and Child Health, Department of Public Health, IRCCS - Istituto di Ricerche Farmacologiche &quot;Mario Negri&quot;, Milan, Italy.
AN  - 25156577
AU  - Ruggiero,
AU  - S.
AU  - Clavenna,
AU  - A.
AU  - Reale,
AU  - L.
AU  - Capuano
AU  - Rossi
AU  - Bonati
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.euroneuro.2014.08.001
DP  - Ovid Technologies
J2  - Eur Neuropsychopharmacol
LA  - English
N1  - Ruggiero, Simona Clavenna, Antonio Reale, Laura Capuano, Annalisa Rossi, Francesco Bonati, Maurizio S0924-977X(14)00228-4
PY  - 2014
SP  - 1578-90
T2  - European Neuropsychopharmacology
TI  - Guanfacine for attention deficit and hyperactivity disorder in pediatrics: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25156577 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25156577&amp;id=doi:10.1016%2Fj.euroneuro.2014.08.001&amp;issn=0924-977X&amp;isbn=&amp;volume=24&amp;issue=10&amp;spage=1578&amp;pages=1578-90&amp;date=2014&amp;title=European+Neuropsychopharmacology&amp;atitle=Guanfacine+for+attention+deficit+and+hyperactivity+disorder+in+pediatrics%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Ruggiero&amp;pid=%3Cauthor%3ERuggiero+S%3C%2Fauthor%3E%3CAN%3E25156577%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0924977X14002284/1-s2.0-S0924977X14002284-main.pdf?_tid=f902c77a-18db-11e5-8e07-00000aacb361&amp;acdnat=1434977056_5351e10bdd1a9f6b84bb438130eefc67
VL  - 24
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Depressive disorders are highly prevalent, have a detrimental impact on the quality of life of patients and their relatives and are associated with increased mortality rates, high levels of service use and substantial economic costs. Current treatments are estimated to only reduce about one-third of the disease burden of depressive disorders. Prevention may be an alternative strategy to further reduce the disease burden of depression. 

**METHODS:** 
We conducted a meta-analysis of randomized controlled trials examining the effects of preventive interventions in participants with no diagnosed depression at baseline on the incidence of diagnosed depressive disorders at follow-up. We identified 32 studies that met our inclusion criteria. 

**RESULTS: **
We found that the relative risk of developing a depressive disorder was incidence rate ratio = 0.79 (95% confidence interval: 0.69-0.91), indicating a 21% decrease in incidence in prevention groups in comparison with control groups. Heterogeneity was low (I(2) = 24%). The number needed to treat (NNT) to prevent one new case of depressive disorder was 20. Sensitivity analyses revealed no differences between type of prevention (e.g. selective, indicated or universal) nor between type of intervention (e.g. cognitive behavioural therapy, interpersonal psychotherapy or other). However, data on NNT did show differences. 

**CONCLUSIONS:** 
Prevention of depression seems feasible and may, in addition to treatment, be an effective way to delay or prevent the onset of depressive disorders. Preventing or delaying these disorders may contribute to the further reduction of the disease burden and the economic costs associated with depressive disorders.
AD  - van Zoonen,Kim. Department of Clinical Psychology and EMGO Institute for Health and Care Research, VU University, Amsterdam, The Netherlands, Leuphana University Innovation Incubator, Division Health Trainings Online, Luneburg, Germany, Philips University, Department of Psychology, Clinical Psychology and Psychotherapy, Marburg, Germany, Trimbos Institute (Netherlands Institute of Mental Health and Addiction), Utrecht, The Netherlands, Department of Epidemiology and Biostastics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA and Department of Psychiatry and EMGO Institute for Health and Care Research, VU University, Amsterdam, The Netherlands.
AN  - 24760873
AU  - van
AU  - Zoonen,
AU  - K.
AU  - Buntrock,
AU  - C.
AU  - Ebert,
AU  - D.
AU  - D.
AU  - Smit,
AU  - F.
AU  - Reynolds,
AU  - C.
AU  - F.
AU  - Beekman,
AU  - A.
AU  - T.
AU  - Cuijpers,
AU  - P.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1093/ije/dyt175
DP  - Ovid Technologies
J2  - Int J Epidemiol
KW  - Adolescent Adult Aged Depressive Disorder, Major/ep [Epidemiology] *Depressive Disorder, Major/pc [Prevention &amp; Control] Female Global Health Humans Incidence Male Middle Aged *Psychotherapy/mt [Methods] Randomized Controlled Trials as Topic Risk Factor
L1  - internal-pdf://0964200389/Zoonen-2014-Preventing the onset of major depr.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural Review
N1  - van Zoonen, Kim Buntrock, Claudia Ebert, David Daniel Smit, Filip Reynolds, Charles F 3rd Beekman, Aartjan T F Cuijpers, Pim Comment in: MMW Fortschr Med. 2014 Oct 23;156(18):36; PMID: 25464538 P30 MH090333 (United States NIMH NIH HHS) P30MH90333 (United States NIMH NIH HHS) UL1 TR000005 (United States NCATS NIH HHS)
PY  - 2014
SP  - 318-29
T2  - International Journal of Epidemiology
TI  - Preventing the onset of major depressive disorder: a meta-analytic review of psychological interventions
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24760873
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24760873&amp;id=doi:10.1093%2Fije%2Fdyt175&amp;issn=0300-5771&amp;isbn=&amp;volume=43&amp;issue=2&amp;spage=318&amp;pages=318-29&amp;date=2014&amp;title=International+Journal+of+Epidemiology&amp;atitle=Preventing+the+onset+of+major+depressive+disorder%3A+a+meta-analytic+review+of+psychological+interventions.&amp;aulast=van+Zoonen&amp;pid=%3Cauthor%3Evan+Zoonen+K%3C%2Fauthor%3E%3CAN%3E24760873%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023317/pdf/dyt175.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023317/pdf/dyt175.pdf
VL  - 43
ER  -
TY  - JOUR
AB  - **Background: **
Clinicians obtain critical prescribing knowledge from clinical papers and review articles. This is the first published systematic review of clinical atomoxetine data covering 2009-2011. 

**Objective:**
We aim to update clinicians on current clinical atomoxetine data with specific reference to time of onset of efficacy and maximal efficacy. These data may allow critical analysis of comparative efficacy between atomoxetine and stimulant medications. 

**Methods: **
A formal systematic review of atomoxetine data from January 2009-June 2011 was conducted. The search term used was &quot;atomoxetine&quot; in the English language. The search yielded 747 citations from which 106 are clinical data. This paper includes clinical efficacy and safety data and excludes quality-of-life and review papers.

**Results:**
Atomoxetine has an onset of action within 4 weeks (possibly within 1 week in subsequent responders) but requires at least 12 weeks for full response to be demonstrated. Treatment-naive cohorts (6-12 weeks) report effect sizes of 0.6-1.3. Using minimum 6-week clinical trial criteria, atomoxetine may demonstrate similar efficacy to methylphenidate comparing reduction in core ADHD symptoms in meta-analysis, although the diversity of the data makes interpretation complex. From epidemiological databases, cardiovascular and suicide-related events were similar to those seen in patients taking methylphenidate. 

**Conclusions:** 
Incremental response time to atomoxetine should be considered in the design of future comparative efficacy trials.
AD  - [Bushe, Chris J.; Savill, Nicola C.] Eli Lilly &amp; Co Ltd, Basingstoke RG24 9NL, Hants, England. Bushe, CJ (reprint author), Eli Lilly &amp; Co Ltd, Lilly House,Priestley Rd, Basingstoke RG24 9NL, Hants, England. bushe_chris@lilly.com
AN  - WOS:000332060100002
AU  - Bushe,
AU  - C.
AU  - J.
AU  - Savill,
AU  - N.
AU  - C.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0269881113478475
J2  - J. Psychopharmacol.
KW  - atomoxetine suicide related ADHD systematic review methylphenidate ADJUNCT OROS-METHYLPHENIDATE DEFICIT/HYPERACTIVITY DISORDER YOUNG-ADULTS CARDIOVASCULAR EVENTS DOUBLE-BLIND ADHD DRUGS OPEN-LABEL CHILDREN METAANALYSIS TOLERABILITY Clinical Neurology Ne
L1  - internal-pdf://3393145343/Bushe-2014-Systematic review of atomoxetine da.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AB8SK Times Cited: 4 Cited Reference Count: 51 Bushe, Chris J. Savill, Nicola C. 4 SAGE PUBLICATIONS LTD LONDON J PSYCHOPHARMACOL
PY  - 2014
SP  - 204-211
T2  - Journal of Psychopharmacology
TI  - Systematic review of atomoxetine data in childhood and adolescent attention-deficit hyperactivity disorder 2009-2011: Focus on clinical efficacy and safety
UR  - &lt;Go to ISI&gt;://WOS:000332060100002http://jop.sagepub.com/content/28/3/204.full.pdf
UR  - http://journals.sagepub.com/doi/pdf/10.1177/0269881113478475
VL  - 28
ER  -
TY  - JOUR
AB  - There is some evidence indicating that psychotropic medications might lead to health-related quality of life (QOL) improvements among children and adolescents with psychiatric disorders. 

The aim of this systematic review is to assess evidence regarding whether antidepressant treatment improves QOL among children and adolescents with depressive or anxiety disorders. 

A comprehensive search resulted in 5 clinical trials to be included in this review: 4 trials with major depressive disorder (MDD) and 1 trial with social anxiety disorder (SAD). In one MDD trial, fluoxetine combined with cognitive behavior therapy (CBT) significantly improved QOL compared to fluoxetine or CBT alone (effect sizes were 0.53 and 0.69, respectively). In 2 combined trials, sertraline alone significantly improved QOL among adolescents with MDD (effect size was 0.29), but not among children with MDD. 

Essentially, it was observed that antidepressants in these trials had minor positive effects on QOL improvement, which were lower than their potential to improve depressive symptoms. 
Although fluoxetine with CBT or sertraline monotherapy were shown to have some potential to improve QOL, this systematic review found inconclusive evidence that antidepressant treatments improve QOL among children and adolescents with depressive or anxiety disorders. 

More research is required, considering that QOL is currently under-evaluated in clinical trials with antidepressants among children and adolescents and available trials have limited methodological quality when reporting QOL data.
AD  - [Stevanovic, Dejan] Gen Hosp Sombor, Dept Psychiat, Sombor 25000, Serbia. [Tadic, Ivana] Univ Belgrade, Fac Pharm, Dept Social Pharm &amp; Pharm Legislat, Belgrade, Serbia. [Knez, Rajna] Rijeka Univ Hosp Ctr, Dept Psychiat, Rijeka, Croatia. Stevanovic, D (reprint author), Gen Hosp Sombor, Dept Psychiat, Apatinski Put 38, Sombor 25000, Serbia. dejanstevanovic@eunet.rs
AN  - WOS:000337748000006
AU  - Stevanovic,
AU  - D.
AU  - Tadic,
AU  - I.
AU  - Knez,
AU  - R.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1017/S1092852913000576
J2  - CNS Spectr.
KW  - Anxiety disorders clinical trial depression efficacy quality of life MAJOR DEPRESSIVE DISORDER PATIENT-REPORTED OUTCOMES ATTENTION-DEFICIT/HYPERACTIVITY DISORDER SEROTONIN REUPTAKE INHIBITORS ROUTINE SPECIALIST CARE COST-EFFECTIVENESS ANXIETY DISORDERS
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AJ5SM Times Cited: 0 Cited Reference Count: 56 Stevanovic, Dejan Tadic, Ivana Knez, Rajna CAMBRIDGE UNIV PRESS NEW YORK CNS SPECTRUMS
PY  - 2014
SP  - 134-141
T2  - Cns Spectrums
TI  - Are antidepressants effective in quality of life improvement among children and adolescents? A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000337748000006http://journals.cambridge.org/action/displayAbstract?fromPage=online&amp;aid=9216268&amp;fileId=S1092852913000576http://journals.cambridge.org/download.php?file=%2F8894_1E528F64C5E033F62B143EC0A85A2090_journals__CNS_CNS19_02_S1092852913000576a.pdf&amp;cover=Y&amp;code=b6878cf21f5f682b91802b67ab63f032
UR  - https://www.cambridge.org/core/journals/cns-spectrums/article/are-antidepressants-effective-in-quality-of-life-improvement-among-children-and-adolescents-a-systematic-review/37FF41F0E6AB73B5033C53076AD11711
VL  - 19
ER  -
TY  - JOUR
AB  - **Objective **
To systematically review the evidence (and quality) for distraction and hypnosis for needle-related pain and distress in children and adolescents. To explore the effects of distraction characteristics (e.g., adult involvement, type of distracter), child age, and study risk of bias on treatment efficacy. 

**Methods **
26 distraction and 7 hypnosis trials were included and self-report, observer-report, and behavioral pain intensity and distress examined. Distraction studies were coded for 4 intervention characteristics, and all studies coded for child age and study risk of bias. 

**Results** 
Findings showed strong support for distraction and hypnosis for reducing pain and distress from needle procedures. The quality of available evidence was low, however. Characteristics of distraction interventions, child age, and study risk of bias showed some influence on treatment efficacy. 

**Conclusions **
Distraction and hypnosis are efficacious in reducing needle-related pain and distress in children. The quality of trials in this area needs to be improved.
AD  - [Birnie, Kathryn A.; Chambers, Christine T.; Uman, Lindsay S.; McGrath, Patrick J.] Dalhousie Univ, Dept Psychol &amp; Neurosci, Halifax, NS B3H 3J5, Canada. [Birnie, Kathryn A.; Parker, Jennifer A.; Chambers, Christine T.; McGrath, Patrick J.] IWK Hlth Ctr, Ctr Pediat Pain Res, Halifax, NS B3K 6R8, Canada. [Noel, Melanie] Seattle Childrens Res Inst, Ctr Child Hlth Behav &amp; Dev, Seattle, WA USA. [Chambers, Christine T.; McGrath, Patrick J.] Dalhousie Univ, Dept Pediat, Halifax, NS B3H 3J5, Canada. [Uman, Lindsay S.] IWK Hlth Ctr, Mental Hlth Serv, Halifax, NS B3K 6R8, Canada. [Uman, Lindsay S.] IWK Hlth Ctr, Addict Serv, Halifax, NS B3K 6R8, Canada. [Kisely, Steve R.] Univ Queensland, Sch Populat Hlth, Brisbane, Qld 4072, Australia. Birnie, KA (reprint author), IWK Hlth Ctr, Ctr Pediat Pain Res, K8536 8th Floor,Childrens Site,5850-5980 Univ Ave, Halifax, NS B3K 6R8, Canada. kbirnie@dal.ca
AN  - WOS:000343398100003
AU  - Birnie,
AU  - K.
AU  - A.
AU  - Noel,
AU  - M.
AU  - Parker,
AU  - J.
AU  - A.
AU  - Chambers,
AU  - C.
AU  - T.
AU  - Uman,
AU  - L.
AU  - S.
AU  - Kisely,
AU  - S.
AU  - R.
AU  - McGrath,
AU  - P.
AU  - J.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1093/jpepsy/jsu029
J2  - J. Pediatr. Psychol.
KW  - distraction distress empirically supported treatments hypnosis needles pain randomized controlled trials RANDOMIZED CONTROLLED-TRIALS EXAMINING PSYCHOLOGICAL INTERVENTIONS PEDIATRIC CANCER-PATIENTS MOUNTED DISPLAY HELMET COLD PRESSOR PAIN PROCEDURAL PAI
L1  - internal-pdf://1373298455/Birnie-2014-Systematic Review and Meta-Analysi.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AR2FD Times Cited: 2 Cited Reference Count: 85 Birnie, Kathryn A. Noel, Melanie Parker, Jennifer A. Chambers, Christine T. Uman, Lindsay S. Kisely, Steve R. McGrath, Patrick J. Kisely, Steve/B-4680-2012 Kisely, Steve/0000-0003-4021-2924 IWK Health Centre; Canadian Institutes of Health Research (CIHR); Post-PhD Fellowship from CIHR; CIHR; Canada Foundation for Innovation The Cochrane Review, which this work extends, was funded in part by a grant from the IWK Health Centre awarded to L.S.U. K.A.B. is a Vanier Canada Graduate Scholar funded by the Canadian Institutes of Health Research (CIHR). M.N. is supported by a Post-PhD Fellowship from CIHR. K. A. B. and M.N. are trainee members of Pain in Child Health: a strategic training initiative through CIHR. C.T.C. is a Canada Research Chair and her research is funded by CIHR and the Canada Foundation for Innovation. 2 OXFORD UNIV PRESS INC CARY J PEDIATR PSYCHOL SI
PY  - 2014
SP  - 783-808
T2  - Journal of Pediatric Psychology
TI  - Systematic Review and Meta-Analysis of Distraction and Hypnosis for Needle-Related Pain and Distress in Children and Adolescents
UR  - &lt;Go to ISI&gt;://WOS:000343398100003http://jpepsy.oxfordjournals.org/content/39/8/783.longhttp://jpepsy.oxfordjournals.org/content/39/8/783.full.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138805/pdf/jsu029.pdf
VL  - 39
ER  -
TY  - JOUR
AB  - School-based interventions are considered a promising effort to prevent the occurrence of mental disorders in adolescents. 

This systematic review focuses on school-based prevention interventions on depression and anxiety disorders utilizing an RCT design, starting from the year 2000. 

Based on an online search (PubMed, Scirus, OVID, ISI) and bibliographic findings in the eligible articles, 28 studies providing information were reviewed. The search process ended on 2 May 2011. 

The majority of interventions turn out to be effective, both for depression (65%) and anxiety (73%). However, the obtained overall mean effect sizes calculated from the most utilized questionnaires can be considered rather small (CDI: -0.12; RCMAS: -0.29). 

The majority of the reviewed school-based interventions shows effectiveness in reducing or preventing mental disorders in adolescents. However, effect size computation revealed only small-scale effectiveness. 

Future studies have to consider the impact of program implementation variations. 

(PsycINFO Database Record (c) 2016 APA, all rights reserved)
AD  - Corrieri, Sandro: sandro.corrieri@medizin.uni-leipzig.de Corrieri, Sandro: Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Philipp-Rosenthal-Str. 55, Leipzig, Germany, 04103, sandro.corrieri@medizin.uni-leipzig.de Corrieri, Sandro: Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany Heider, Dirk: Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany Conrad, Ines: Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany Blume, Anne: Department of Psychiatry, University of Leipzig, Leipzig, Germany Konig, Hans-Helmut: Department of Medical Sociology and Health Economics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany Riedel-Heller, Steffi G.: Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany
AN  - 2014-34680-004
AU  - Corrieri,
AU  - S.
AU  - Heider,
AU  - D.
AU  - Conrad,
AU  - I.
AU  - Blume,
AU  - A.
AU  - Konig,
AU  - H.
AU  - H.
AU  - Riedel-Heller,
AU  - S.
AU  - G.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.researchgate.net/publication/235397133_School-based_prevention_programs_for_depression_and_anxiety_in_adolescence_A_systematic_review
DP  - Ovid Technologies
KW  - adolescents, evaluation, prevention, mental health
KW  - *Adolescent Psychopathology
KW  - *Anxiety
KW  - *Major Depression
KW  - *Mental Health
KW  - *School Based Intervention
KW  - Drug Abuse Prevention
KW  - Mental Disorders
KW  - Curriculum &amp; Programs &amp; Teaching Methods [3530]
KW  - Adolescent
KW  - Anxiety
KW  - Depression
KW  - Humans
KW  - Psychology, Adolescent
KW  - School Health Services
KW  - Surveys and Questionnaires
KW  - Human
L1  - internal-pdf://2197796476/267.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2014
SP  - 427-441
T2  - Health Promotion International
TI  - School-based prevention programs for depression and anxiety in adolescence: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc11&amp;AN=2014-34680-004http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1093%2Fheapro%2Fdat001&amp;issn=0957-4824&amp;isbn=&amp;volume=29&amp;issue=3&amp;spage=427&amp;pages=427-441&amp;date=2014&amp;title=Health+Promotion+International&amp;atitle=School-based+prevention+programs+for+depression+and+anxiety+in+adolescence%3A+A+systematic+review.&amp;aulast=Corrieri&amp;pid=%3Cauthor%3ECorrieri%2C+Sandro%3C%2Fauthor%3E%3CAN%3E2014-34680-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 29
ER  -
TY  - JOUR
AB  - Mindfulness programs for schools are popular. We systematically reviewed the evidence regarding the effects of school based mindfulness interventions on psychological outcomes, using a comprehensive search strategy designed to locate both published and unpublished studies. Systematic searches in 12 databases were performed in August 2012. 
Further studies were identified via hand search and contact with experts. Two reviewers independently extracted the data, also selecting information about intervention programs (elements, structure etc.), feasibility, and acceptance. 

Twenty-four studies were identified, of which 13 were published. Nineteen studies used a controlled design. In total, 1348 students were instructed in mindfulness, with 876 serving as controls, ranging from grade 1 to 12. Overall effect sizes were Hedge&#039;s g=0.40 between groups and g=0.41 within groups (p&lt;0.0001). Between group effect sizes for domains were: cognitive performance g=0.80, stress g=0.39, resilience g=0.36, (allp&lt;0.05), emotional problems g=0.19 third person ratings g=0.25 (bothn. s.). 

All in all, mindfulness-based interventions in children and youths hold promise, particularly in relation to improving cognitive performance and resilience to stress. However, the diversity of study samples, variety in implementation and exercises, and wide range of instruments used require a careful and differentiated examination of data. There is great heterogeneity, many studies are under powered, and measuring effects of Mindfulness in this setting is challenging. 

The field is nascent and recommendations will be provided as to how interventions and research of these interventions may proceed.
AD  - [Zenner, Charlotte; Herrnleben-Kurz, Solveig; Walach, Harald] European Univ Viadrina, Inst Transcultural Hlth Studies, D-15207 Frankfurt, Germany. Walach, H (reprint author), European Univ Viadrina, Inst Transcultural Hlth Studies, Grosse Scharrnstr 59, D-15207 Frankfurt, Germany. walach@europa-uni.de
AN  - WOS:000338730300001
AU  - Zenner,
AU  - C.
AU  - Herrnleben-Kurz,
AU  - S.
AU  - Walach,
AU  - H.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3389/fpsyg.2014.00603
J2  - Front. Psychol.
KW  - mindfulness children meta-analysis systematic review stress school-age resilience STRESS REDUCTION COGNITIVE THERAPY MEDITATION PROGRAM ADOLESCENTS CHILDREN STUDENTS BEHAVIOR OUTCOMES IMPACT Psychology, Multidisciplinary
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AK9EL Times Cited: 0 Cited Reference Count: 88 Zenner, Charlotte Herrnleben-Kurz, Solveig Walach, Harald FRONTIERS RESEARCH FOUNDATION LAUSANNE FRONT PSYCHOL
PY  - 2014
SP  - 20
T2  - Frontiers in Psychology
TI  - Mindfulness-based interventions in schools-a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000338730300001http://journal.frontiersin.org/article/10.3389/fpsyg.2014.00603/pdf
VL  - 5
ER  -
TY  - JOUR
AB  - This systematic review examines train the trainer (TTT) effectiveness trials of behavioral interventions for individuals with autism spectrum disorder (ASD). 

Published methodological quality scales were used to assess studies including participant description, research design, intervention, outcomes, and analysis. 

Twelve studies including 9 weak quality quasi-experimental studies, 2 single-subject experimental design studies of moderate and weak quality, and 1 high quality randomized control trial were included. 

Overall, author reported effect sizes and calculation of improvement rate difference for SSRDs indicate positive effects of intervention across participant outcomes including cognition, language, and autism symptoms postcommunity delivered interventions primarily based in applied behavior analysis. 
Effects varied by children&#039;s developmental level.
AD  - [Shire, Stephanie Yoshiko; Kasari, Connie] Univ Calif Los Angeles, Los Angeles, CA 90095 USA. Shire, SY (reprint author), Univ Calif Los Angeles, Neuropsychiat Inst 67 448, 760 Westwood Plaza, Los Angeles, CA 90095 USA. sypatterson@ucla.edu
AN  - WOS:000341271000004
AU  - Shire,
AU  - S.
AU  - Y.
AU  - Kasari,
AU  - C.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1352/1944-7558-119.5.436
J2  - AJIDD-Am. J. Intellect. Dev. Disabil.
KW  - effectiveness trials Train-the-Trainer autism intervention JOINT ATTENTION INTERVENTION SPECTRUM DISORDERS PSYCHOSOCIAL INTERVENTIONS FOLLOW-UP CHILDREN PSYCHOTHERAPY PRESCHOOLERS PROGRAM MODEL Education, Special Rehabilitation
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AO3XQ Times Cited: 0 Cited Reference Count: 34 Shire, Stephanie Yoshiko Kasari, Connie AMER ASSOC INTELLECTUAL DEVELOPMENTAL DISABILITIES WASHINGTON AJIDD-AM J INTELLECT
PY  - 2014
SP  - 436-451
T2  - Ajidd-American Journal on Intellectual and Developmental Disabilities
TI  - Train the Trainer Effectiveness Trials of Behavioral Intervention for Individuals With Autism: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000341271000004http://media.proquest.com/media/pq/classic/doc/3432181761/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Shire%2C+Stephanie+Yoshiko%3BKasari%2C+Connie&amp;cit%3Atitle=Train+the+Trainer+Effectiveness+Trials+of+Behavioral+Intervention+for+...&amp;cit%3Apub=American+Journal+on+Intellectual+and+Developmental+Disabilities&amp;cit%3Avol=119&amp;cit%3Aiss=5&amp;cit%3Apg=436&amp;cit%3Adate=Sep+2014&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYxOTEwMzYyOTY3Njo2NjQ1NzgSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioGODA2MzQ2MgoxNTYxOTkzNDAxOg1Eb2N1bWVudEltYWdlQgEwUgZPbmxpbmVaAkZUYgNQRlRqCjIwMTQvMDkvMDFyCjIwMTQvMTAvMzF6AIIBKVAtMTAwMDI3My0zMTA3NS1DVVNUT01FUi0xMDAwMDE1Ny0xMTE1MTEykgEGT25saW5lygEHRW5kTm90ZdIBElNjaG9sYXJseSBKb3VybmFsc5oCB1ByZVBhaWSqAihPUzpFTVMtUGRmRG9jVmlld0Jhc2UtZ2V0TWVkaWFVcmxGb3JJdGVtygIPQXJ0aWNsZXxGZWF0dXJl0gIBWeICAU7yAgA%3D&amp;_s=BaFOF%2FmS2PBvFaHYAPh%2B2wWlCdI%3D
UR  - http://www.aaiddjournals.org/doi/abs/10.1352/1944-7558-119.5.436?code=aamr-site
VL  - 119
ER  -
TY  - JOUR
AB  - **PURPOSE: **
A meta-analysis comparing the efficacy and acceptability of selective serotonin reuptake inhibitors (SSRIs) versus tricyclic antidepressants (TCAs) in depressed children, adolescents, and young adults was performed. 

**METHODS: **
A comprehensive literature search of the PubMed, Cochrane, Embase, Web of Science, and PsycINFO databases was conducted from 1970 to December 2013. Only clinical trials that randomly assigned one SSRI or TCA to patients aged 7 to 25 years who met the diagnostic criteria for unipolar depressive disorder were included. Primary efficacy was determined by the pooling of standardized mean differences (SMDs) calculated from the difference in the reduction in mean depression rating scale scores for the 2 antidepressants. Acceptability was determined by pooling the risk ratios (RRs) of dropouts for all reasons and for adverse effects as well as the suicide-risk outcome. 

**FINDINGS: **
Five trials with a total of 422 patients were considered to be eligible for inclusion. SSRIs were significantly more effective than TCAs in primary efficacy (SMD = -0.52; 95% CI, -0.81 to -0.24; P = 0.0003). Patients taking SSRIs had a significantly greater response to depressive symptoms than patients taking TCAs (RR = 1.55; 95% CI, 1.04 to 2.29; P = 0.03). On an individual SSRI basis, fluoxetine had a significantly greater efficacy than TCAs (SMD = -0.82; 95% CI, -1.34 to -0.29; P = 0.003). On an individual TCA basis, only imipramine was not significantly worse than SSRIs (SMD = -0.27; 95% CI, -0.56 to 0.02; P = 0.06). Significantly more patients taking TCAs discontinued treatment than patients taking SSRIs (35.8% vs 25.1%; RR = 0.70; 95% CI, 0.52 to 0.93; P = 0.02). 

**IMPLICATIONS: **
SSRI therapy has a superior efficacy and is better tolerated compared with TCA therapy in young patients.

Copyright &copy; 2014 Elsevier HS Journals, Inc. All rights reserved.
AD  - Qin,Bin. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China. Zhang,Yuqing. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China. Zhou,Xinyu. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China. Cheng,Pengfei. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China. Liu,Yiyun. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China. Chen,Jin. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China. Fu,Yuying. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China. Luo,Qinghua. Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China. Xie,Peng. Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; Institute of Neuroscience, Chongqing Medical University, Chongqing, China; Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China. Electronic address: xiepeng973@126.com.
AN  - 24998011
AU  - Qin,
AU  - B.
AU  - Zhang,
AU  - Y.
AU  - Zhou,
AU  - X.
AU  - Cheng,
AU  - P.
AU  - Liu,
AU  - Y.
AU  - Chen,
AU  - J.
AU  - Fu,
AU  - Y.
AU  - Luo,
AU  - Q.
AU  - Xie,
AU  - P.
DA  - Jul 1
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.clinthera.2014.06.001
DP  - Ovid Technologies
J2  - Clin Ther
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Qin, Bin Zhang, Yuqing Zhou, Xinyu Cheng, Pengfei Liu, Yiyun Chen, Jin Fu, Yuying Luo, Qinghua Xie, Peng S0149-2918(14)00353-1
PY  - 2014
SP  - 1087-1095.e4
T2  - Clinical Therapeutics
TI  - Selective serotonin reuptake inhibitors versus tricyclic antidepressants in young patients: a meta-analysis of efficacy and acceptability
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24998011 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24998011&amp;id=doi:10.1016%2Fj.clinthera.2014.06.001&amp;issn=0149-2918&amp;isbn=&amp;volume=36&amp;issue=7&amp;spage=1087&amp;pages=1087-1095.e4&amp;date=2014&amp;title=Clinical+Therapeutics&amp;atitle=Selective+serotonin+reuptake+inhibitors+versus+tricyclic+antidepressants+in+young+patients%3A+a+meta-analysis+of+efficacy+and+acceptability.&amp;aulast=Qin&amp;pid=%3Cauthor%3EQin+B%3C%2Fauthor%3E%3CAN%3E24998011%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0149291814003531/1-s2.0-S0149291814003531-main.pdf?_tid=bb95e33a-1972-11e5-a602-00000aab0f6c&amp;acdnat=1435041806_7bc5f840d3cebb054bd6f09572077b53
VL  - 36
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Reducing waiting anxiety is an important objective of patient-centered care. Anxiety is linked to negative health outcomes, including longer recovery periods, lowered pain thresholds, and for children in particular, resistance to treatment, nightmares, and separation anxiety. The goals of this study were (1) to systematically review published research aimed at reducing preprocedural waiting anxiety, and (2) to provide directions for future research and development of strategies to manage preprocedural waiting anxiety in health care environments. 

**METHODS:**
We performed a systematic review of the literature via 151 Web of Knowledge, PubMed, PsycINFO, EMBASE, CINAHL, and Medline. Included in this review were studies describing measurable outcomes in response to interventions specifically intended to improve the waiting experience of patients in health care settings. Primary outcomes of interest were stress and anxiety. Exclusion criteria included (a) studies aimed at reducing wait times and management of waiting lists only, (b) waiting in non health care settings, (c) design of health care facilities with nonspecific strategies pertaining to waiting spaces, (d) strategies to reduce pain or anxiety during the course of medical procedures, and (e) interventions such as massage, acupuncture, or hypnosis that require dedicated staff and/or private waiting environments to administer. 

**RESULTS:** 
We identified 8690 studies. Forty-one articles met the inclusion criteria. In adult populations, 33 studies were identified, wherein the effects of music (n = 25), aromatherapy (n = 6), and interior design features (n = 2) were examined. Eight pediatric studies were identified investigating play opportunities (n = 2), media distractions (n = 2), combined play opportunities and media distractions (n = 3), and music (n = 1). Based on results from 1129 adult participants in the 14 studies that evaluated music and permitted meta-analysis, patients who listened to music before a medical procedure exhibited a lowered-state anxiety (-5.1 +/- 0.53 points on the State Trait Anxiety Scale) than those who received standard care. The efficacy of aromatherapy was inconclusive. Studies reporting on the impact of improved interior design of waiting areas, while positive, are minimal and heterogeneous. For children, insufficient evidence is available to corroborate the effectiveness of play opportunities, media distractions, and music for mitigating anxiety in children awaiting medical procedures. 

**CONCLUSIONS: **
Music is a well-established means of decreasing anxiety in adult patients awaiting medical interventions. The effect of music on children&#039;s anxiety is not known. Limited studies and heterogeneity of interventions and methods in the areas of aromatherapy, interior design, digital media, and play opportunities (for children) suggest the need for future research.
AD  - [Biddiss, Elaine; Knibbe, Tara Joy; McPherson, Amy] Holland Bloorview Kids Rehabil Hosp, Bloorview Res Inst, Toronto, ON M4G 1R8, Canada. [Biddiss, Elaine] Univ Toronto, Inst Biomat &amp; Biomed Engn, Toronto, ON, Canada. [McPherson, Amy] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada. Biddiss, E (reprint author), Holland Bloorview Kids Rehabil Hosp, Bloorview Res Inst, 150 Kilgour Rd, Toronto, ON M4G 1R8, Canada. ebiddiss@hollandbloorview.ca
AN  - WOS:000339455900026
AU  - Biddiss,
AU  - E.
AU  - Knibbe,
AU  - T.
AU  - J.
AU  - McPherson,
AU  - A.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1213/ane.0000000000000294
J2  - Anesth. Analg.
KW  - PREOPERATIVE ANXIETY PASSIVE DISTRACTION PATIENT ANXIETY DENTAL FEAR MUSIC CHILDREN SURGERY PAIN STRESS ENVIRONMENT Anesthesiology
L1  - internal-pdf://2431734160/Biddiss-2014-The Effectiveness of Intervention.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AL9IX Times Cited: 0 Cited Reference Count: 82 Biddiss, Elaine Knibbe, Tara Joy McPherson, Amy Canadian Institutes of Health Research Canadian Institutes of Health Research. LIPPINCOTT WILLIAMS &amp; WILKINS PHILADELPHIA ANESTH ANALG
PY  - 2014
SP  - 433-448
T2  - Anesthesia and Analgesia
TI  - The Effectiveness of Interventions Aimed at Reducing Anxiety in Health Care Waiting Spaces: A Systematic Review of Randomized and Nonrandomized Trials
UR  - &lt;Go to ISI&gt;://WOS:000339455900026http://graphics.tx.ovid.com/ovftpdfs/FPDDNCLBMEJCKF00/fs046/ovft/live/gv025/00000539/00000539-201408000-00026.pdf
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCDCKGDIMI00/fs046/ovft/live/gv025/00000539/00000539-201408000-00026.pdf
VL  - 119
ER  -
TY  - JOUR
AB  - This review presents findings from an overview of meta-analyses of the effects of prevention and promotion programs to prevent mental health, substance use, and conduct problems. 

The review of 48 meta-analyses found small but significant changes that reduce depression, anxiety, antisocial behavior, and substance use. 

Furthermore, the results were sustained over time. Meta-analyses often found that the effects were heterogeneous. 

A conceptual model is proposed to guide the study of moderators of program effects in future meta-analyses, and methodological issues in synthesizing findings across preventive interventions are discussed.
AD  - [Sandler, Irwin; Wolchik, Sharlene A.; Mahrer, Nicole E.] Arizona State Univ, Dept Psychol, Tempe, AZ 85287 USA. [Sandler, Irwin; Wolchik, Sharlene A.; Mahrer, Nicole E.] Arizona State Univ, Prevent Res Ctr, Tempe, AZ 85287 USA. [Cruden, Gracelyn; Brincks, Ahnalee; Brown, C. Hendricks] Northwestern Univ, Feinberg Sch Med, Dept Psychiat &amp; Behav Sci, Chicago, IL 60611 USA. [Ahn, Soyeon] Univ Miami, Coll Educ, Coral Gables, FL 33146 USA. Sandler, I (reprint author), Arizona State Univ, Dept Psychol, Tempe, AZ 85287 USA. irwin.sandler@asu.edu
AN  - WOS:000336428200011
AU  - Sandler,
AU  - I.
AU  - Wolchik,
AU  - S.
AU  - A.
AU  - Cruden,
AU  - G.
AU  - Mahrer,
AU  - N.
AU  - E.
AU  - Ahn,
AU  - S.
AU  - Brincks,
AU  - A.
AU  - Brown,
AU  - C.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1146/annurev-clinpsy-050212-185524
J2  - Annu. Rev. Clin. Psychol.
KW  - prevention meta-analysis mental health substance use COLLEGE-STUDENT DRINKING SCHOOL-BASED PREVENTION DEPRESSIVE SYMPTOMS ANTISOCIAL-BEHAVIOR SMOKING PREVENTION DRUG PREVENTION CLINICAL-TRIALS SOCIAL-SKILLS EFFECT SIZES PROGRAMS Psychology, Clinical Psy
L1  - internal-pdf://1766073140/Sandler-2014-Overview of Meta-Analyses of the.pdf
LA  - English
M3  - Article; Book Chapter
N1  - ISI Document Delivery No.: BA4XX Times Cited: 1 Cited Reference Count: 83 Sandler, Irwin Wolchik, Sharlene A. Cruden, Gracelyn Mahrer, Nicole E. Ahn, Soyeon Brincks, Ahnalee Brown, C. Hendricks Cannon, TD Widiger, T 1 ANNUAL REVIEWS PALO ALTO 978-0-8243-3910-4 ANNU REV CLIN PSYCHO
PY  - 2014
SP  - 243-273
T2  - Annual Review of Clinical Psychology, Vol 10
TI  - Overview of Meta-Analyses of the Prevention of Mental Health, Substance Use, and Conduct Problems
UR  - &lt;Go to ISI&gt;://WOS:000336428200011http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984908/pdf/nihms555277.pdf
UR  - http://www.annualreviews.org/doi/10.1146/annurev-clinpsy-050212-185524
VL  - 10
ER  -
TY  - JOUR
AB  - **Background:** 
Drug addiction is a chronic, relapsing disease. Primary interventions should aim to reduce first use or to prevent the transition from experimental use to addiction. School is the appropriate setting for preventive interventions.

**Objectives:** 
To evaluate the effectiveness of universal school-based interventions in reducing drug use compared to usual curricular activities or no intervention.

**Search methods:** 
We searched the Cochrane Drugs and Alcohol Group&#039;s Trials Register (September 2013), the Cochrane Central Register of Controlled Trials (2013, Issue 9), PubMed (1966 to September 2013), EMBASE (1988 to September 2013) and other databases. We also contacted researchers in the field and checked reference lists of articles.

**Selection criteria:** 
Randomised controlled trials (RCT) evaluating school-based interventions designed to prevent illicit drugs use.

**Data collection and analysis:** 
We used the standard methodological procedures expected by The Cochrane Collaboration.

**Main results:** 
We included 51 studies, with 127,146 participants. Programmes were mainly delivered in sixth and seventh grade pupils. Most of the trials were conducted in the USA. Social competence approach versus usual curricula or no interventionMarijuana use at &lt; 12 months follow-up: the results favoured the social competence intervention (risk ratio (RR) 0.90; 95% confidence interval (CI) 0.81 to 1.01, four studies, 9456 participants, moderate quality evidence). Seven studies assessed this outcome (no data for meta-analysis): two showed a positive significant effect of intervention, three showed a non-significant effect, one found a significant effect in favour of the control group and one found a trend in favour of the control group.Marijuana use at 12+ months: the results favoured the social competence intervention (RR 0.86; 95% CI 0.74 to 1.00, one study, 2678 participants, high quality evidence). Seven studies assessed this outcome (no data for meta-analysis): two showed a significant positive effect of intervention, three showed a non-significant effect, one found a significant effect in favour of the control group and one a trend in favour of the control group.Hard drug use at &lt; 12 months: we found no difference (RR 0.69; 95% CI 0.40 to 1.18, one study, 2090 participants, moderate quality evidence). Two studies assessed this outcome (no data for meta-analysis): one showed comparable results for the intervention and control group; one found a statistically non-significant trend in favour of the social competence approach.Hard drug use at 12+ months: we found no difference (mean difference (MD) -0.01; 95% CI -0.06 to 0.04), one study, 1075 participants, high quality evidence). One study with no data for meta-analysis showed comparable results for the intervention and control group.Any drug use at &lt; 12 months: the results favoured social competence interventions (RR 0.27; 95% CI 0.14 to 0.51, two studies, 2512 participants, moderate quality evidence). One study with 1566 participants provided continuous data showing no difference (MD 0.02; 95% CI -0.05 to 0.09, moderate quality evidence). Social influence approach versus usual curricula or no interventionMarijuana use at &lt; 12 months: we found a nearly statistically significant effect in favour of the social influence approach (RR 0.88; 95% CI 0.72 to 1.07, three studies, 10,716 participants, moderate quality evidence). One study with 764 participants provided continuous data showing results that favoured the social influence intervention (MD -0.26; 95% CI -0.48 to -0.04).Marijuana use at 12+ months: we found no difference (RR 0.95; 95% CI 0.81 to 1.13, one study, 5862 participants, moderate quality evidence). One study with 764 participants provided continuous data and showed nearly statistically significant results in favour of the social influence intervention (MD -0.22; 95% CI -0.46 to 0.02). Of the four studies not providing data for meta-analysis a statistically significant protective effect was only found by one study.Hard drug use at 12+ months: one study not providing data for meta- n lysis found a significant protective effect of the social influence approach.Any drug use: no studies assessed this outcome. Combined approach versus usual curricula or no interventionMarijuana use at &lt; 12 months: there was a trend in favour of intervention (RR 0.79; 95% CI 0.59 to 1.05, three studies, 8701 participants, moderate quality evidence). One study with 693 participants provided continuous data and showed no difference (MD -1.90; 95% CI -5.83 to 2.03).Marijuana use at 12+ months: the results favoured combined intervention (RR 0.83; 95% CI 0.69 to 0.99, six studies, 26,910 participants, moderate quality evidence). One study with 690 participants provided continuous data and showed no difference (MD -0.80; 95% CI -4.39 to 2.79). Two studies not providing data for meta-analysis did not find a significant effect.Hard drug use at &lt; 12 months: one study with 693 participants provided both dichotomous and continuous data and showed conflicting results: no difference for dichotomous outcomes (RR 0.85; 95% CI 0.63 to 1.14), but results in favour of the combined intervention for the continuous outcome (MD -3.10; 95% CI -5.90 to -0.30). The quality of evidence was high.Hard drug use at 12+ months: we found no difference (RR 0.86; 95% CI 0.39 to 1.90, two studies, 1066 participants, high quality evidence). One study with 690 participants provided continuous data and showed no difference (MD 0.30; 95% CI -1.36 to 1.96). Two studies not providing data for meta-analysis showed a significant effect of treatment.Any drug use at &lt; 12 months: the results favoured combined intervention (RR 0.76; 95% CI 0.64 to 0.89, one study, 6362 participants).Only one study assessed the effect of a knowledge-focused intervention on drug use and found no effect. The types of comparisons and the programmes assessed in the other two groups of studies were very heterogeneous and difficult to synthesise.

**Authors&#039; conclusions:** 
School programmes based on a combination of social competence and social influence approaches showed, on average, small but consistent protective effects in preventing drug use, even if some outcomes did not show statistical significance. Some programmes based on the social competence approach also showed protective effects for some outcomes.Since the effects of school-based programmes are small, they should form part of more comprehensive strategies for drug use prevention in order to achieve a population-level impact.
AN  - CD003020
AU  - Faggiano,
AU  - F.
AU  - Minozzi,
AU  - S.
AU  - Versino,
AU  - E.
AU  - Buscemi,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003020.pub3
KW  - School Health Services
KW  - Controlled Clinical Trials as Topic
KW  - Marijuana Abuse [prevention &amp; control]
KW  - Program Evaluation
KW  - Randomized Controlled Trials as Topic
KW  - Substance-Related Disorders [prevention &amp; control]
KW  - Adolescent[checkword]
KW  - Humans[checkword]
KW  - Addictn
PY  - 2014
T2  - Cochrane Database of Systematic Reviews
TI  - Universal school-based prevention for illicit drug use
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003020.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003020.pub3/asset/CD003020.pdf?v=1&amp;t=iw7ldlzi&amp;s=081afa5557be9ffc861d91e1791834ad7366cc5e
ER  -
TY  - JOUR
AB  - &#039;*Background:** 
Every year a large number of children around the world are removed from their homes because they are maltreated. Child welfare agencies are responsible for placing these children in out-of-home settings that will facilitate their safety, permanency, and well-being. However, children in out-of-home placements typically display more educational, behavioural, and psychological problems than do their peers, although it is unclear whether this results from the placement itself, the maltreatment that precipitated it, or inadequacies in the child welfare system.

**Objectives:** 
To evaluate the effect of kinship care placement compared to foster care placement on the safety, permanency, and well-being of children removed from the home for maltreatment.

**Search methods:** 
We searched the following databases for this updated review on 14 March 2011: the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, PsycINFO, CINAHL, Sociological Abstracts, Social Science Citation Index, ERIC, Conference Proceedings Citation Index-Social Science and Humanities, ASSIA, and Dissertation Express. We handsearched relevant social work journals and reference lists of published literature reviews, and contacted authors.

**Selection criteria:** 
Controlled experimental and quasi-experimental studies, in which children removed from the home for maltreatment and subsequently placed in kinship foster care were compared with children placed in non-kinship foster care for child welfare outcomes in the domains of well-being, permanency, or safety.

**Data collection and analysis:** 
Two review authors independently read the titles and abstracts identified in the searches, and selected appropriate studies. Two review authors assessed the eligibility of each study for the evidence base and then evaluated the methodological quality of the included studies. Lastly, we extracted outcome data and entered them into Review Manager 5 software (RevMan) for meta-analysis with the results presented in written and graphical forms.

**Main results:** 
One-hundred-and-two quasi-experimental studies, with 666,615 children are included in this review. The &#039;Risk of bias&#039; analysis indicates that the evidence base contains studies with unclear risk for selection bias, performance bias, detection bias, reporting bias, and attrition bias, with the highest risk associated with selection bias and the lowest associated with reporting bias. The outcome data suggest that children in kinship foster care experience fewer behavioural problems (standardised mean difference effect size -0.33, 95% confidence interval (CI) -0.49 to -0.17), fewer mental health disorders (odds ratio (OR) 0.51, 95% CI 0.42 to 0.62), better well-being (OR 0.50, 95% CI 0.38 to 0.64), and less placement disruption (OR 0.52, 95% CI 0.40 to 0.69) than do children in non-kinship foster care. For permanency, there was no difference on reunification rates, although children in non-kinship foster care were more likely to be adopted (OR 2.52, 95% CI 1.42 to 4.49), while children in kinship foster care were more likely to be in guardianship (OR 0.26, 95% CI 0.17 to 0.40). Lastly, children in non-kinship foster care were more likely to utilise mental health services (OR 1.79, 95% CI 1.35 to 2.37).

**Authors&#039; conclusions:** 
This review supports the practice of treating kinship care as a viable out-of-home placement option for children removed from the home for maltreatment. However, this conclusion is tempered by the pronounced methodological and design weaknesses of the included studies.
AN  - CD006546
AU  - Winokur,
AU  - M.
AU  - Holtan,
AU  - A.
AU  - Batchelder,
AU  - K.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2014.2
KW  - Child Abuse [psychology]
KW  - Child Welfare [psychology]
KW  - Family
KW  - Friends
KW  - Child Behavior Disorders [epidemiology]
KW  - Child Development
KW  - Foster Home Care [methods] [psychology] [standards]
KW  - Safety
KW  - Child[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Behav
PY  - 2014
T2  - Cochrane Database of Systematic Reviews
TI  - Kinship care for the safety, permanency, and well-being of children removed from the home for maltreatment
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006546.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006546.pub3/asset/CD006546.pdf?v=1&amp;t=iw7jxfyu&amp;s=de7422fcfbd63be00ee245b19f69221719a2cd69
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Relative to youth in regular high schools, alternative high school (AHS) youth are at high risk for alcohol, tobacco, and other drug (ATOD) misuse. Prevention and cessation efforts are needed for this population. 

**METHODS:** 
A systematic, exhaustive literature search was completed to identify ATOD misuse prevention and cessation research studies with AHS youth. 

**RESULTS:** For the AHS population, 23 ATOD misuse prevention or cessation program evaluations were located. This review indicated that successful efforts have focused on instruction in motivation enhancement, life coping skills, and decision making. 

**CONCLUSIONS:** 
Alcohol, tobacco, and other drug misuse prevention and cessation programming for AHSs is effective, delivered in the classroom or as a school-based clinic. There is little evidence, though, that this programming is effective when delivered through other modalities such as via computer or bridging beyond the school setting. More research and application of evidence-based programming are recommended for youth in AHS settings.

Copyright &copy; 2014, American School Health Association.
AD  - Sussman,Steve. Preventive Medicine, Psychology, and Social Work, Institute for Health Promotion and Disease Prevention Research, University of Southern California Soto Street Building, 2001 North Soto Street, Room 302A, Los Angeles, CA 90032. ssussma@usc.edu.
AN  - 25274175
AU  - Sussman,
AU  - S.
AU  - Arriaza,
AU  - B.
AU  - Grigsby,
AU  - T.
AU  - J.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/josh.12200
DP  - Ovid Technologies
J2  - J Sch Health
L1  - internal-pdf://2414543808/Sussman-2014-Alcohol, tobacco, and other drug.pdf
LA  - English
M3  - Research Support, N.I.H., Extramural
N1  - Sussman, Steve Arriaza, Bridget Grigsby, Timothy J DA020138 (United States NIDA NIH HHS) T32 CA009492 (United States NCI NIH HHS)
PY  - 2014
SP  - 748-58
T2  - Journal of School Health
TI  - Alcohol, tobacco, and other drug misuse prevention and cessation programming for alternative high school youth: a review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25274175
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25274175&amp;id=doi:10.1111%2Fjosh.12200&amp;issn=0022-4391&amp;isbn=&amp;volume=84&amp;issue=11&amp;spage=748&amp;pages=748-58&amp;date=2014&amp;title=Journal+of+School+Health&amp;atitle=Alcohol%2C+tobacco%2C+and+other+drug+misuse+prevention+and+cessation+programming+for+alternative+high+school+youth%3A+a+review.&amp;aulast=Sussman&amp;pid=%3Cauthor%3ESussman+S%3C%2Fauthor%3E%3CAN%3E25274175%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/josh.12200/asset/josh12200.pdf?v=1&amp;t=ib3jp2tb&amp;s=b03d9f470b89feacf48b1200747cfb377e9b797b
UR  - http://onlinelibrary.wiley.com/doi/10.1111/josh.12200/abstract
UR  - http://onlinelibrary.wiley.com/store/10.1111/josh.12200/asset/josh12200.pdf?v=1&amp;t=j8yeye8i&amp;s=a65fe766305b5c3e5c661bf8608c5320a08afe53
VL  - 84
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Serious parental mental illness poses a challenge to quality of life (QoL) in a substantial number of children and adolescents. Improving the lives of these children is a political and public health concern.

**OBJECTIVES:** 
To conduct an evidence synthesis of the clinical effectiveness, cost-effectiveness and acceptability of community-based interventions for improving QoL in children of parents with serious mental illness (SMI).

**DATA SOURCES:** 
Nineteen health, allied health and educational databases, searched from database inception to May 2012, and supplemented with hand searches, reference checking, searches of grey literature, dissertations, ongoing research registers, forward citation tracking and key author contact.

**REVIEW METHODS:** 
Inclusion criteria required&gt;=50% of parents to have SMI or severe depression confirmed by clinical diagnosis or baseline symptoms. Children were &lt;=18 years of age. Community-based interventions included any non-residential psychological/psychosocial intervention involving parents or children for the purposes of improving health or well-being. Intervention comparators were not predefined and primary outcomes were validated measures of children&#039;s QoL and emotional health. Secondary outcomes were derived from UK policy and stakeholder consultation. Data were extracted independently by two reviewers and the study quality was assessed via Cochrane criteria for randomised/non-randomised designs, Critical Appraisal Skills Programme (CASP) qualitative criteria or a standard checklist for economic evaluations. Separate syntheses were conducted for SMI and severe depression. Standardised effect size (ES) trials were pooled using random-effects modelling for which sufficient data were available. Economic data were summarised and acceptability data were synthesised via a textual narrative approach.RESULTS: Three trials targeted mothers/the children of mothers with psychotic symptoms. Children were &lt;=12 years of age and no primary QoL or emotional health outcomes were reported. Insufficient secondary outcome data prevented pooling and no eligible economic evaluations were found. Twenty-six trials targeted parents/children of parents with severe depression; 18 recruited mothers of infants&lt;2.5 years of age. Data pooling suggested no significant short-term effect on children&#039;s emotional health [standardised ES 0.06, 95% confidence interval (CI) -0.20 to 0.33] or social function (standardised ES 0.23, 95% CI 0.00 to 0.46). Medium to large effects were observed for parents&#039; depressive symptoms (standardised ES 0.73, 95% CI 0.51 to 0.94) and parenting behaviours (standardised ES 0.67, 95% CI 0.32 to 1.02). One non-randomised economic evaluation was found. Intervention uptake and adherence were inconsistently reported. Incomplete evidence highlighted potential barriers from child custody losses and conflicting life circumstances. Qualitative data suggesting interventions to overcome social isolation and stigma are well received by parents. Limited data suggested that children may value peer interactions and normalising activities.LIMITATIONS: Included trials were of poor or unclear quality with inadequate randomisation or allocation concealment, possible attrition biases and incomplete outcome reporting. Meaningful analysis was challenged by clinical and methodological heterogeneity and insufficient data for subgroup comparisons. Children&#039;s self-reports were lacking and evidence of effect remains biased towards parent-based interventions for severely depressed mothers of infants. Generalisability to other diagnoses, older children and children of fathers with SMI is unclear. A lack of high-quality economic data prevented economic modelling.

**CONCLUSION:** 
Evidence for community-based interventions to enhance QoL in children of SMI parents is lacking. The capacity to recommend evidence-based approaches is limited. Rigorous development work is needed to establish feasible and acceptable child- and family-based interventions, prior to evaluating clinical effectiveness and cost-effectiveness via a randomised controlled trial (RCT). A substantial programme of pilot work is recommended to underpin the development of feasible and acceptable interventions for this population. Evaluations should incorporate validated, child-centred QoL outcome measures, high-quality cost data and nested, in-depth acceptability studies. New age-appropriate instruments that better reflect the life priorities and unique challenges faced by children of parents with SMI may need to be developed.FUNDING: This report was commissioned by the NHS R&amp;D Health Technology Assessment programme and funded by the National Institute for Health Research Health Technology Assessment programme.
AD  - Bee, Penny. School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK.Bower, Peter. NIHR School for Primary Care Research, Manchester Academic Health Science Centre, Centre for Primary Care, Institute of Population Health, University of Manchester, Manchester, UK.Byford, Sarah. Centre for the Economics of Mental and Physical Health, Institute of Psychiatry, King&#039;s College London, London, UK.Churchill, Rachel. Centre for Mental Health, University of Bristol, Bristol, UK.Calam, Rachel. School of Psychological Sciences, University of Manchester, Manchester, UK.Stallard, Paul. Department for Health, University of Bath, Bath, UK.Pryjmachuk, Steven. School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK.Berzins, Kathryn. School of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK.Cary, Maria. Centre for the Economics of Mental and Physical Health, Institute of Psychiatry, King&#039;s College London, London, UK.Wan, Ming. Centre for Women&#039;s Health, Institute of Brain, Behaviour and Mental Health, University of Manchester, Manchester, UK.Abel, Kathryn. Centre for Women&#039;s Health, Institute of Brain, Behaviour and Mental Health, University of Manchester, Manchester, UK.
AN  - 24502767
AU  - Bee,
AU  - P.
AU  - Bower,
AU  - P.
AU  - Byford,
AU  - S.
AU  - Churchill,
AU  - R.
AU  - Calam,
AU  - R.
AU  - Stallard,
AU  - P.
AU  - Pryjmachuk,
AU  - S.
AU  - Berzins,
AU  - K.
AU  - Cary,
AU  - M.
AU  - Wan,
AU  - M.
AU  - Abel,
AU  - K.
DA  - Feb
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3310/hta18080
DP  - Ovid Technologies
J2  - Health Technol Assess
KW  - Adolescent
KW  - Child
KW  - *Child Welfare/px [Psychology]
KW  - *Child of Impaired Parents/px [Psychology]
KW  - Child, Preschool
KW  - Cost-Benefit Analysis
KW  - Depressive Disorder, Major/ep [Epidemiology]
KW  - Health Status
KW  - Humans
KW  - Infant
KW  - Infant, Newborn
KW  - *Mental Disorders/ep [Epidemiology]
KW  - Mental Health
KW  - *Quality of Life
KW  - State Medicine
KW  - United Kingdom
L1  - internal-pdf://2055283422/Bee.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
Review
Systematic Review
N1  - Bee, PennyBower, PeterByford, SarahChurchill, RachelCalam, RachelStallard, PaulPryjmachuk, StevenBerzins, KathrynCary, MariaWan, MingAbel, KathrynComment in (CIN)
PY  - 2014
SP  - 1-250
T2  - Health Technology Assessment (Winchester, England)
TI  - The clinical effectiveness, cost-effectiveness and acceptability of community-based interventions aimed at improving or maintaining quality of life in children of parents with serious mental illness: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=24502767
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24502767&amp;id=doi:10.3310%2Fhta18080&amp;issn=1366-5278&amp;isbn=&amp;volume=18&amp;issue=8&amp;spage=1&amp;pages=1-250&amp;date=2014&amp;title=Health+Technology+Assessment+%28Winchester%2C+England%29&amp;atitle=The+clinical+effectiveness%2C+cost-effectiveness+and+acceptability+of+community-based+interventions+aimed+at+improving+or+maintaining+quality+of+life+in+children+of+parents+with+serious+mental+illness%3A+a+systematic+review.&amp;aulast=Bee&amp;pid=%3Cauthor%3EBee+P%3C%2Fauthor%3E%3CAN%3E24502767%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 18
ER  -
TY  - JOUR
AB  - Children who have been adopted or fostered are at high risk of experiencing interpersonal difficulties and placement breakdown may occur if these difficulties are not addressed through interventions. 

The aim of this review was to identify the impact of attachment interventions with foster and adoptive parents on children&#039;s behavioural, emotional and relational functioning. 

A systematic search process was undertaken; electronic databases were searched; key journals were hand searched; reference lists of included articles were searched; and authors who have published work in the field were contacted. 

Ten studies met the inclusion criteria. There is some evidence to support the positive impact of these interventions for children, particularly young children aged six months to six years. However, overall, the studies were of relatively poor methodological quality, making conclusions about the efficacy of these interventions difficult. 

Further research is therefore required to draw clearer conclusions about the impact of attachment interventions for fostered and adopted children. 

Copyright (c) 2014 John Wiley &amp; Sons, Ltd. KEY PRACTITIONER MESSAGES: 

A number of the reviewed studies reported positive outcomes in child behavioural functioning and to a lesser degree in emotional and relational functioning following intervention. Interventions focused on constructs such as parental sensitivity, attunement to the child and the impact of abuse and neglect on attachment to new caregivers. When quality criteria were applied, two studies focused on children aged six months to six years were found to be methodologically strong, providing some evidence for the benefit of early attachment- based interventions within this population.
AD  - [Kerr, Laura; Cossar, Jill] Univ Edinburgh, Sect Clin &amp; Hlth Psychol, Sch Med, Edinburgh EH8 9AG, Midlothian, Scotland. Kerr, L (reprint author), Univ Edinburgh, Sect Clin &amp; Hlth Psychol, Sch Med, Teviot Pl, Edinburgh EH8 9AG, Midlothian, Scotland. laurakerr4@nhs.net
AN  - WOS:000346959800005
AU  - Kerr,
AU  - L.
AU  - Cossar,
AU  - J.
DA  - Nov-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/car.2313
J2  - Child Abus. Rev.
KW  - adoption attachment foster care interventions MENTAL-HEALTH PREVENTIVE INTERVENTION CHILDREN INFANTS CARE FAMILIES TRAUMA PSYCHOTHERAPY DIFFICULTIES METAANALYSIS Family Studies Social Work
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AX5IN Times Cited: 1 Cited Reference Count: 63 Kerr, Laura Cossar, Jill 1 WILEY-BLACKWELL HOBOKEN CHILD ABUSE REV SI
PY  - 2014
SP  - 426-439
T2  - Child Abuse Review
TI  - Attachment Interventions with Foster and Adoptive Parents: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000346959800005http://onlinelibrary.wiley.com/store/10.1002/car.2313/asset/car2313.pdf?v=1&amp;t=ib7nfy0i&amp;s=ad85ac6054e531705f5a9182e092ca9505d2caf8
VL  - 23
ER  -
TY  - JOUR
AB  - Electroencephalogram-recorded epileptiform activity is common in children with autism spectrum disorder (ASD), even without clinical seizures. 

A systematic literature search identified 7 randomized, placebo-controlled trials of antiepileptic drugs (AEDs) in ASD (total n = 171), including three of valproate, and one each of lamotrigine, levetiracetam, and topiramate. 

Meta-analysis revealed no significant difference between medication and placebo in four studies targeting irritability/agitation and three studies investigating global improvement, although limitations include lack of power and different medications with diverse actions. 

Across all seven studies, there was no significant difference in discontinuation rate between two groups. 

AEDs do not appear to have a large effect size to treat behavioral symptoms in ASD, but further research is needed, particularly in the subgroup of patients with epileptiform abnormalities.
AD  - [Hirota, Tomoya; Veenstra-VanderWeele, Jeremy] Vanderbilt Univ, Dept Psychiat, Med Ctr, Nashville, TN 37212 USA. [Hollander, Eric] Albert Einstein Coll Med, Dept Psychiat, Bronx, NY 10467 USA. [Hollander, Eric] Montefiore Med Ctr, Bronx, NY 10467 USA. [Kishi, Taro] Fujita Hlth Univ, Sch Med, Dept Psychiat, Toyoake, Aichi 47011, Japan. Hirota, T (reprint author), Vanderbilt Univ, Dept Psychiat, Med Ctr, 1601 23rd Ave South 3102 VPH, Nashville, TN 37212 USA. tomoya.hirota@vanderbilt.edu
AN  - WOS:000332688900020
AU  - Hirota,
AU  - T.
AU  - Veenstra-VanderWeele,
AU  - J.
AU  - Hollander,
AU  - E.
AU  - Kishi,
AU  - T.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10803-013-1952-2
J2  - J. Autism Dev. Disord.
KW  - Antiepileptic Mood stabilizer Anticonvulsant Autism Pervasive developmental disorder BORDERLINE PERSONALITY-DISORDER PLACEBO-CONTROLLED TRIAL PERVASIVE DEVELOPMENTAL DISORDERS DOUBLE-BLIND DIVALPROEX SODIUM CHILDREN AGGRESSION ADOLESCENTS LEVETIRACETAM
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AC7EB Times Cited: 1 Cited Reference Count: 36 Hirota, Tomoya Veenstra-VanderWeele, Jeremy Hollander, Eric Kishi, Taro 1 SPRINGER/PLENUM PUBLISHERS NEW YORK J AUTISM DEV DISORD
PY  - 2014
SP  - 948-957
T2  - Journal of Autism and Developmental Disorders
TI  - Antiepileptic Medications in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000332688900020http://media.proquest.com/media/pq/classic/doc/3237359241/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Hirota%2C+Tomoya%3BVeenstra-vanderweele%2C+Jeremy%3BHollander%2C+Eric%3BKishi%2C+Taro&amp;cit%3Atitle=Antiepileptic+Medications+in+Autism+Spectrum+Disorder%3A+A+Systematic+Review+and+Meta-Analysis&amp;cit%3Apub=Journal+of+Autism+and+Developmental+Disorders&amp;cit%3Avol=44&amp;cit%3Aiss=4&amp;cit%3Apg=948&amp;cit%3Adate=Apr+2014&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYxOTA4MDgyNDgzODo5NDM0NjkSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNDg0MDEyCjE1MDQzNjAyMzk6DURvY3VtZW50SW1hZ2VCATBSBk9ubGluZVoCRlRiA1BGVGoKMjAxNC8wNC8wMXIKMjAxNC8wNC8zMHoAggEpUC0xMDAwMjczLTMxMDc1LUNVU1RPTUVSLTEwMDAwMTU3LTExMTUxMTKSAQZPbmxpbmXKAQdFbmROb3Rl0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCKE9TOkVNUy1QZGZEb2NWaWV3QmFzZS1nZXRNZWRpYVVybEZvckl0ZW3KAg9BcnRpY2xlfEZlYXR1cmXSAgFZ4gIBTvICAA%3D%3D&amp;_s=kQkuKH6Kr%2By%2FTQCWp8hse5KBGYM%3D
UR  - http://link.springer.com/article/10.1007%2Fs10803-013-1952-2
UR  - https://link.springer.com/article/10.1007%2Fs10803-013-1952-2
VL  - 44
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
We conducted a meta-analysis to examine the association between early intervention and mental or neuromusculoskeletal and movement-related functions of children born low birthweight (LBW) or preterm. 

**METHOD: **
The meta-analysis included 16 studies that yielded 97 effects. Q and I2 values were used to determine heterogeneity. Publication bias was evaluated using Egger&#039;s regression intercept test and a funnel plot. 

**RESULTS:** 
The association between early intervention and either mental or neuromusculoskeletal and movement-related functions yielded a significant but small effect size (d = .219, p &lt; .0001). Heterogeneity was statistically insignificant.

**CONCLUSION: **
Participation in early intervention programs addressing mental or neuromusculoskeletal and movement-related functions in children born LBW or preterm results in significant improvements in these areas.
AD  - (Park) Hae Yean Park, PhD, OT, is Postdoctoral Fellow, Department of Occupational Therapy, Florida International University, Miami (Maitra) Kinsuk Maitra, PhD, OTR/L, is Chair and Professor, Department of Occupational Therapy, Nicole Wertheim College of Nursing and Health Sciences, Florida International University, 11200 SW Eighth Street, MMC, AHC3 443, Miami, FL 33199; kmaitra@fiu.edu (Achon) Jacqueline Achon, OTS, is Graduate Student, Department of Occupational Therapy, Florida International University, Miami (Loyola) Evelyn Loyola, OTS, is Graduate Student, Department of Occupational Therapy, Florida International University, Miami (Rincon) Maria Rincon, OTS, is Graduate Student, Department of Occupational Therapy, Florida International University, Miami
AN  - 24797190
AU  - Park,
AU  - H.
AU  - Y.
AU  - Maitra.
AU  - K.
AU  - Achon,
AU  - J.
AU  - Loyola,
AU  - E.
AU  - Rincon,
AU  - M.
DA  - 2014
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.5014/ajot.2014.010371
DP  - Ovid Technologies
KW  - early intervention human Infant, Premature, Diseases/th [Therapy] low birth weight Mental Disorders/th [Therapy] meta analysis Motor Skills Disorders/th [Therapy] Movement Disorders/th [Therapy] Neuromuscular Diseases/th [Therapy] newborn occupational t
LA  - English
PY  - 2014
SP  - 268-276
T2  - The American journal of occupational therapy
TI  - Effects of early intervention on mental or neuromusculoskeletal and movement-related functions in children born low birthweight or preterm: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed12&amp;AN=24797190
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:24797190&amp;id=doi:10.5014%2Fajot.2014.010371&amp;issn=1943-7676&amp;isbn=&amp;volume=68&amp;issue=3&amp;spage=268&amp;pages=268-276&amp;date=2014&amp;title=The+American+journal+of+occupational+therapy+%3A+official+publication+of+the+American+Occupational+Therapy+Association&amp;atitle=Effects+of+early+intervention+on+mental+or+neuromusculoskeletal+and+movement-related+functions+in+children+born+low+birthweight+or+preterm%3A+a+meta-analysis&amp;aulast=Rincon&amp;pid=%3Cauthor%3ERincon+M.%3C%2Fauthor%3E%3CAN%3E24797190%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3Ehttp://ajot.aota.org/article.aspx?articleid=1867346http://graphics.tx.ovid.com/ovftpdfs/FPDDNCMCCCAAMH00/fs046/ovft/live/gv023/00000448/00000448-201405000-00004.pdf
UR  - https://ajot.aota.org/article.aspx?articleid=1867346
VL  - 68
ER  -
TY  - JOUR
AB  - Peer management intervention is a subtype of peer-mediated intervention that involves training individuals to implement standardized intervention protocols to modify the behavior of their peers. 

This meta-analysis of single-case research synthesized the results of 29 studies examining the effectiveness of school-based peer management interventions. 

The overall results indicate that peer management interventions are moderately effective (Tau-U = 0.78) at altering the behavior of students in the desired direction in a variety of domains including social skills, disruptive behavior, and academic engagement time. 

These results are consistent with similar metar-analyses examining the effects of academic peer-mediated interventions (e.g., Bowman-Perrott et al., 2013). 

Moderator variables including intervention target behavior, student interventionist training time, and matching of target students and student interventionists on a variety of demographic variables were examined. 

Limitations, implications, and future directions of the findings are discussed.
AD  - [Dart, Evan H.] Univ So Mississippi, Dept Psychol, Sch Psychol Program, Hattiesburg, MS 39406 USA. [Collins, Tai A.; McKinley, Lauren E.] Univ Cincinnati, Sch Psychol Program, Cincinnati, OH 45221 USA. [Klingbeil, David A.] Univ Wisconsin, Sch Psychol Program, Milwaukee, WI 53201 USA. Dart, EH (reprint author), Univ So Mississippi, Dept Psychol, Box 5025, Hattiesburg, MS 39406 USA. evan.dart@usm.edu
AN  - WOS:000346879400003
AU  - Dart,
AU  - E.
AU  - H.
AU  - Collins,
AU  - T.
AU  - A.
AU  - Klingbeil,
AU  - D.
AU  - A.
AU  - McKinley,
AU  - L.
AU  - E.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.17105/SPR-14-0009.1
J2  - Sch. Psychol. Rev.
KW  - DEFICIT HYPERACTIVITY DISORDER MEDIATED INTERVENTION SEVERE DISABILITIES SOCIAL INTERACTIONS GROUP CONTINGENCY PUBLICATION BIAS TASK BEHAVIOR MIDDLE SCHOOL AUTISM CHILDREN Psychology, Educational
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AX4BP Times Cited: 0 Cited Reference Count: 59 Dart, Evan H. Collins, Tai A. Klingbeil, David A. McKinley, Lauren E. NATL ASSOC SCHOOL PSYCHOLOGISTS BETHESDA SCHOOL PSYCHOL REV
PY  - 2014
SP  - 367-384
T2  - School Psychology Review
TI  - Peer Management Interventions: A Meta-Analytic Review of Single-Case Research
UR  - &lt;Go to ISI&gt;://WOS:000346879400003
VL  - 43
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Some trials have suggested that bupropion, as well as methylphenidate, is beneficial in the treatment of attention-deficit/hyperactivity disorder (ADHD). 

**OBJECTIVES: **
The purpose of this systematic review was to summarize the efficacy, acceptability, and tolerability of bupropion in comparison with methylphenidate for ADHD treatment. Included studies were randomized controlled trials (RCTs) that compared bupropion and methylphenidate. Clinical studies conducted between January 1991 and January 2014 were reviewed. 

**DATA SOURCES: **
MEDLINE(), EMBASE, CINAHL, PsycINFO(), and the Cochrane Controlled Trials Register were searched in January 2014. Additionally, clinical trials were identified from the databases of ClinicalTrials.gov and the EU Clinical Trials Register. 

**STUDY ELIGIBLE CRITERIA PARTICIPANTS AND INTERVENTIONS: **
All RCTs of bupropion and methylphenidate reporting final outcomes relevant to 1) ADHD severity, 2) response or remission rates, 3) overall discontinuation rate, or 4) discontinuation rate due to adverse events. Language restriction was not applied. 

**STUDY APPRAISAL AND SYNTHESIS METHODS: **
The relevant clinical trials were examined and the data of interest were extracted. Additionally, the risks of bias were also inspected. The efficacy outcomes were the mean changed scores of ADHD rating scales, the overall response rate, and the overall remission rates. The overall discontinuation rate and the discontinuation rate due to adverse events were determined. Relative risks and weighted mean differences or standardized mean differences with 95% confidence intervals were estimated using a random effect model. 

**RESULTS: **
A total of 146 subjects in four RCTs comparing bupropion with methylphenidate in the treatment of ADHD were included. The pooled mean changed scores of the Iowa-Conner&#039;s Abbreviated Parent and Teacher Questionnaires and the ADHD Rating Scale-IV for parents and teachers of children and adolescents with ADHD in the bupropion- and methylphenidate-treated groups were not significantly different. Additionally, the pooled mean changed score in adult ADHD between the two groups, measured by the ADHD Rating Scale-IV and the Adult ADHD Rating Scale, was also not significantly different. The pooled rates of response, overall discontinuation, and discontinuation due to adverse events between the two groups were not significantly different. 

**CONCLUSION: **
Based on limited data from this systematic review, bupropion was as effective as methylphenidate for ADHD patients. Additionally, tolerability and acceptability were also comparable. However, these findings should be considered as very preliminary results. To confirm this evidence, further studies in this area should be conducted.
AD  - Maneeton,Narong. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Maneeton,Benchalak. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Intaprasert,Suthi. Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand. Woottiluk,Pakapan. Psychiatric Nursing Division, Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand.
AN  - 25120365
AU  - Maneeton,
AU  - N.
AU  - ManeetonB.
AU  - Intaprasert,
AU  - S.
AU  - Woottiluk,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2147/NDT.S62714
DP  - Ovid Technologies
J2  - Neuropsychiatr
LA  - English
N1  - Maneeton, Narong Maneeton, Benchalak Intaprasert, Suthi Woottiluk, Pakapan
PY  - 2014
SP  - 1439-49
T2  - Neuropsychiatric Disease &amp; Treatment
TI  - A systematic review of randomized controlled trials of bupropion versus methylphenidate in the treatment of attention-deficit/hyperactivity disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=25120365 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25120365&amp;id=doi:10.2147%2FNDT.S62714&amp;issn=1176-6328&amp;isbn=&amp;volume=10&amp;issue=&amp;spage=1439&amp;pages=1439-49&amp;date=2014&amp;title=Neuropsychiatric+Disease+%26+Treatment&amp;atitle=A+systematic+review+of+randomized+controlled+trials+of+bupropion+versus+methylphenidate+in+the+treatment+of+attention-deficit%2Fhyperactivity+disorder.&amp;aulast=Maneeton&amp;pid=%3Cauthor%3EManeeton+N%3C%2Fauthor%3E%3CAN%3E25120365%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.dovepress.com/getfile.php?fileID=21043
VL  - 10
ER  -
TY  - JOUR
AB  - **Background:** 
Torture is widespread, with potentially broad and long-lasting impact across physical, psychological, social and other areas of life. Its complex and diverse effects interact with ethnicity, gender, and refugee experience. Health and welfare agencies offer varied rehabilitation services, from conventional mental health treatment to eclectic or needs-based interventions. This review is needed because relatively little outcome research has been done in this field, and no previous systematic review has been conducted. Resources are scarce, and the challenges of providing services can be considerable.

**Objectives:** 
To assess beneficial and adverse effects of psychological, social and welfare interventions for torture survivors, and to compare these effects with those reported by active and inactive controls.

**Search methods:** 
Randomised controlled trials (RCTs) were identified through a search of PsycINFO, MEDLINE, EMBASE, Web of Science, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), the Cochrane Central Register of Controlled Trials (CENTRAL) and the Cochrane Depression, Anxiety and Neurosis Specialised Register (CCDANCTR), the Latin American and Caribbean Health Science Information Database (LILACS), the Open System for Information on Grey Literature in Europe (OpenSIGLE), the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP) and Published International Literature On Traumatic Stress (PILOTS) all years to 11 April 2013; searches of Cochrane resources, international trial registries and the main biomedical databases were updated on 20 June 2014. We also searched the Online Library of Dignity (Danish Institute against Torture), reference lists of reviews and included studies and the most frequently cited journals, up to April 2013 but not repeated for 2014. Investigators were contacted to provide updates or details as necessary.

**Selection criteria:** 
Full publications of RCTs or quasi-RCTs of psychological, social or welfare interventions for survivors of torture against any active or inactive comparison condition.

**Data collection and analysis:** 
We included all major sources of grey literature in our search and used standard methodological procedures as expected by The Cochrane Collaboration for collecting data, evaluating risk of bias and using GRADE (Grades of Recommendation, Assessment, Development and Evaluation) methods to assess the quality of evidence.

**Main results:** 
Nine RCTs were included in this review. All were of psychological interventions; none provided social or welfare interventions. The nine trials provided data for 507 adults; none involved children or adolescents. Eight of the nine studies described individual treatment, and one discussed group treatment. Six trials were conducted in Europe, and three in different African countries. Most people were refugees in their thirties and forties; most met the criteria for post-traumatic stress disorder (PTSD) at the outset. Four trials used narrative exposure therapy (NET), one cognitive-behavioural therapy (CBT) and the other four used mixed methods for trauma symptoms, one of which included reconciliation methods. Five interventions were compared with active controls, such as psychoeducation; four used treatment as usual or waiting list/no treatment; we analysed all control conditions together. Duration of therapy varied from one hour to longer than 20 hours with a median of around 12 to 15 hours. All trials reported effects on distress and on PTSD, and two reported on quality of life. Five studies followed up participants for at least six months.No immediate benefits of psychological therapy were noted in comparison with controls in terms of our primary outcome of distress (usually depression), nor for PTSD symptoms, PTSD caseness, or quality of life. At six-month follow-up, three NET and one CBT study (86 participants) showed moderate effect sizes for intervention over control in reduction of distress (standardised mean difference (SMD) -0.63, 95% confidence interval (CI) -1.07 to -0.19) and of T D symptoms (SMD -0.52, 95% CI -0.97 to -0.07). However, the quality of evidence was very low, and risk of bias resulted from researcher/therapist allegiance to treatment methods, effects of uncertain asylum status of some people and real-time non-standardised translation of assessment measures. No measures of adverse events were described, nor of participation, social functioning, quantity of social or family relationships, proxy measures by third parties or satisfaction with treatment. Too few studies were identified for review authors to attempt sensitivity analyses.

**Authors&#039; conclusions:**
Very low-quality evidence suggests no differences between psychological therapies and controls in terms of immediate effects on post-traumatic symptoms, distress or quality of life; however, NET and CBT were found to confer moderate benefits in reducing distress and PTSD symptoms over the medium term (six months after treatment). Evidence was of very low quality, mainly because non-standardised assessment methods using interpreters were applied, and sample sizes were very small. Most eligible trials also revealed medium to high risk of bias. Further, attention to the cultural appropriateness of interventions or to their psychometric qualities was inadequate, and assessment measures used were unsuitable. As such, these findings should be interpreted with caution.No data were available on whether symptom reduction enabled improvements in quality of life, participation in community life, or in social and family relationships in the medium term. Details of adverse events and treatment satisfaction were not available immediately after treatment nor in the medium term. Future research should aim to address these gaps in the evidence and should include larger sample sizes when possible. Problems of torture survivors need to be defined far more broadly than by PTSD symptoms, and recognition given to the contextual influences of being a torture survivor, including as an asylum seeker or refugee, on psychological and social health.
AN  - CD009317
AU  - Patel,
AU  - N.
AU  - Kellezi,
AU  - B.
AU  - de
AU  - C.
AU  - Williams,
AU  - A.
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009317.pub2
KW  - Mental Health
KW  - Cognitive Therapy [methods]
KW  - Human Rights [education]
KW  - Narrative Therapy [methods]
KW  - Psychotherapy [methods]
KW  - Psychotherapy, Group
KW  - Quality of Life [psychology]
KW  - Randomized Controlled Trials as Topic
KW  - Refugees [psychology]
KW  - Resilience, Psychological
KW  - Stress Disorders, Post-Traumatic [psychology] [therapy]
KW  - Stress, Psychological [psychology] [therapy]
KW  - Torture [psychology]
KW  - Adult[checkword]
KW  - Humans[checkword]
KW  - Depressn
L1  - internal-pdf://3877235676/Patel-2014-Psychological, social and welfare i.pdf
PY  - 2014
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological, social and welfare interventions for psychological health and well-being of torture survivors
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009317.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009317.pub2/asset/CD009317.pdf?v=1&amp;t=iw7kv7xo&amp;s=79f9a0f0e2561513a3e6e8293c07fcb4920d1eba
ER  -
TY  - JOUR
AB  - Pediatric bipolar spectrum disorders (BPSDs) are serious conditions associated with morbidity and mortality. Although most treatment research has examined pharmacotherapy for pediatric BPSDs, growing literature suggests that psychosocial interventions are also important to provide families with an understanding of symptoms, course, and treatment of BPSDs; teach youth and parents methods for coping with symptoms (e.g., problem solving, communication, emotion regulation, cognitive-behavioral skills); and prevent relapse. 

Thirteen psychosocial intervention trials for pediatric BPSDs were identified via a comprehensive literature search and evaluated according to the Task Force on the Promotion and Dissemination of Psychological Procedures guidelines. All interventions were examined adjunctive to pharmacotherapy and/or treatment as usual (TAU). No well-established or questionably efficacious treatments were identified. Family psychoeducation plus skill building was probably efficacious (i.e., Multi-Family Psychoeducational Psychotherapy, Family-Focused Treatment); cognitive-behavioral therapy (CBT) was possibly efficacious. Dialectical behavior therapy (DBT) and interpersonal and social rhythm therapy (IPSRT) were experimental. 

Limited research precluded subdivision of treatments by format and age. Only single- and multiple-family psychoeducation plus skill building and CBT were evaluated with children. Only single-family psychoeducation plus skill building and DBT, and individual (commonly with limited familial involvement) CBT and IPSRT were evaluated with adolescents. 

In conclusion, psychosocial interventions that involve families, psychoeducation, and skill building may offer added benefit to pharmacotherapy and/or other TAU. Limitations of current research include few outcome studies, small samples, and failure to use stringent control conditions or randomization. The review concludes with a discussion of mediators and moderators, recommendations for best practice, and suggestions for future research.
AD  - Fristad,Mary A. a Departments of Psychiatry Psychology, and Nutrition , The Ohio State University.
AN  - 23927375
AU  - Fristad,
AU  - M.
AU  - A.
AU  - MacPherson,
AU  - H.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/15374416.2013.822309
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
KW  - Adaptation, Psychological Adolescent Adult Bipolar Disorder/px [Psychology] *Bipolar Disorder/th [Therapy] Child *Cognitive Therapy/mt [Methods] *Evidence-Based Medicine Family/px [Psychology] *Family Therapy/mt [Methods] Humans Middle Aged Secondary Pr
LA  - English
M3  - Research Support, N.I.H., Extramural Review
N1  - Fristad, Mary A MacPherson, Heather A R01 MH073801 (United States NIMH NIH HHS) R34 MH085875 (United States NIMH NIH HHS) R34 MH090148 (United States NIMH NIH HHS) R34MH085875 (United States NIMH NIH HHS)
PY  - 2014
SP  - 339-55
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Evidence-based psychosocial treatments for child and adolescent bipolar spectrum disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23927375
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23927375&amp;id=doi:10.1080%2F15374416.2013.822309&amp;issn=1537-4416&amp;isbn=&amp;volume=43&amp;issue=3&amp;spage=339&amp;pages=339-55&amp;date=2014&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Evidence-based+psychosocial+treatments+for+child+and+adolescent+bipolar+spectrum+disorders.&amp;aulast=Fristad&amp;pid=%3Cauthor%3EFristad+MA%3C%2Fauthor%3E%3CAN%3E23927375%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/15374416.2013.822309
VL  - 43
ER  -
TY  - JOUR
AB  - **Objective:  **
To review published reports on Web-based treatment and prevention programs for depression, anxiety, and suicide prevention in children, adolescents, and emerging adults. 

 **Method:  **
A systematic search of the PsycINFO, PubMed, Medline, and Web of Science databases was conducted in December 2013. Programs were classified according to evidence-base level (Well-Established, Probably Efficacious, Possibly Efficacious, Experimental, and Of Questionable Efficacy). 

 **Results: **
Of the 14,001 citations initially identified, 25 articles met inclusion criteria for Web-based interventions. These described 9 programs, of which 8 were Internet based and 1 was a mobile application. No Web-based interventions for suicide prevention were identified. Of the randomized controlled trials (n = 14) and open trials (n = 3) identified, 10 reported significant postintervention reductions in symptoms of depression and/or anxiety or improvements in diagnostic ratings, with small to large effect sizes. Many of these studies also reported significant improvements at follow-up. The methodological quality of the studies varied. Many programs were limited by their small sample sizes and use of waitlist or no-treatment control groups. 

 **Conclusion:  **
There is limited evidence for the effectiveness of Web-based interventions for youth depression and anxiety. Additional research and program development are needed to fill the current gaps in the literature.
AD  - [Reyes-Portillo, Jazmin A.; Mufson, Laura; Greenhill, Laurence L.; Gould, Madelyn S.; Fisher, Prudence W.; Tarlow, Naomi; Rynn, Moira A.] Columbia Univ Med Ctr, New York State Psychiat Inst, New York, NY USA. Reyes-Portillo, JA (reprint author), 1051 Riverside Dr, New York, NY 10032 USA. reyespo@nyspi.columbia.edu
AN  - WOS:000345808600003
AU  - Reyes-Portillo,
AU  - J.
AU  - A.
AU  - Mufson,
AU  - L.
AU  - Greenhill,
AU  - L.
AU  - L.
AU  - Gould,
AU  - M.
AU  - S.
AU  - Fisher,
AU  - P.
AU  - W.
AU  - Tarlow,
AU  - N.
AU  - Rynn,
AU  - M.
AU  - A.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jaac.2014.09.005
J2  - J. Am. Acad. Child Adolesc. Psychiatr.
KW  - Web-based intervention emerging adult depression anxiety RANDOMIZED CONTROLLED-TRIAL DEPRESSION PREVENTION INTERVENTION NATIONAL COMORBIDITY SURVEY COGNITIVE-BEHAVIOR THERAPY MENTAL-HEALTH-SERVICES PRIMARY-CARE ANXIETY DISORDERS CLINICAL-TRIAL ADOLESCEN
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AU7WG Times Cited: 0 Cited Reference Count: 58 Reyes-Portillo, Jazmin A. Mufson, Laura Greenhill, Laurence L. Gould, Madelyn S. Fisher, Prudence W. Tarlow, Naomi Rynn, Moira A. Sallie Foundation Child and Adolescent Mental Health Technology Program Postdoctoral Fellowship This review was supported by the Sallie Foundation Child and Adolescent Mental Health Technology Program Postdoctoral Fellowship ELSEVIER SCIENCE BV AMSTERDAM J AM ACAD CHILD PSY
PY  - 2014
SP  - 1254-1270
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Web-Based Interventions for Youth Internalizing Problems: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000345808600003http://ac.els-cdn.com/S089085671400656X/1-s2.0-S089085671400656X-main.pdf?_tid=4f974594-1674-11e5-8ebe-00000aab0f26&amp;acdnat=1434712631_22ea2bab8910114367099f946d9ba31f
VL  - 53
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To comprehensively evaluate the efficacy and safety of atomoxetine (ATX) in pediatric attention-deficit/hyperactivity disorder (ADHD). 

**METHOD:** 
Meta-analysis of all double-blind randomized controlled trials (DBRCTs) evaluating the efficacy and tolerability of ATX for ADHD. Pooled, random-effects analyses were conducted, calculating standardized mean difference (SMD), yielding effect sizes (ES), relative risk (RR), and number-needed-to-treat/harm (NNT/NNH).Moderator/mediator analyses were also conducted, including metaregression. 

**RESULTS: **
Across 25 DBRCTs (56 treatment arms, N = 3,928), ATX outperformed placebo regarding overall ADHD symptoms (ES = -0.64, 95% confidence interval [CI] = -0.56 to -0.71, p &lt; 0.0001), hyperactivity/impulsivity (ES = -0.67, CI = -0.53 to -0.81, p &lt; 0.0001), and inattention (ES = -0.59, CI = -0.51 to -0.67, p &lt; 0.0001). Altogether, 44.4% versus 21.4% of patients improved by &gt;40% (NNT = 4), whereas 39.9% versus 65.9% improved by &lt;25% (NNT = 4). Oppositional defiant disorder symptoms (ES = -0.33) and quality-of-life-related outcomes (ES = -0.48 to -0.25) improved somewhat less. A higher percentage of treatment-naive patients moderated the efficacy of ATX for overall ADHD symptoms (p = 0.017). All-cause discontinuation with ATX was similar to that for placebo (p = 1.00), with lower discontinuation because of inefficacy (relative risk [RR] = 0.51, CI = 0.36-0.74, p &lt; 0.0001, NNT = 34), but higher discontinuation because of adverse effects (AEs) (RR = 1.89, CI = 1.08-3.31, p = 0.03, NNH = 50) with ATX. At least 1 adverse effect (AE) (70.4% versus 56.1%, p &lt; 0.01, NNH = 6) and &gt;1 psychiatric AE (21.5% versus 7.4%, NNH = 7, p &lt; 0.01) were more frequent with ATX, whereas serious AEs (1.5% versus 1.0%), aggression (7.5% versus 6.0%), and suicidal ideation (1.3% versus 0.9%) were not different from placebo. 

**CONCLUSIONS: **
Short-term ATX treatment is safe and superior to placebo for overall ADHD symptoms and key secondary outcomes, with a medium ES. However, a relevant patient subgroup (40%) continues to have significant symptomatology, requiring additional clinical attention.

Copyright &copy; 2014 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
AD  - Schwartz,Shimon. Zucker Hillside Hospital, Psychiatry Research, North Shore-Long Island Jewish (LIJ) Health System, and Montefiore Medical Center. Correll,Christoph U. Zucker Hillside Hospital, Psychiatry Research, North Shore-Long Island Jewish Health System, Hofstra North Shore-LIJ School of Medicine, Albert Einstein College of Medicine, and the Feinstein Institute for Medical Research. Electronic address: ccorrell@lij.edu.
AN  - 24472252
AU  - Schwartz,
AU  - S.
AU  - Correll,
AU  - C.
AU  - U.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2013.11.005
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
LA  - English
N1  - Schwartz, Shimon Correll, Christoph U Comment in: J Am Acad Child Adolesc Psychiatry. 2014 Feb;53(2):135-7; PMID: 24472248 Comment in: Evid Based Ment Health. 2014 Nov;17(4):108; PMID: 25165169 S0890-8567(13)00814-9
PY  - 2014
SP  - 174-87
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Efficacy and safety of atomoxetine in children and adolescents with attention-deficit/hyperactivity disorder: results from a comprehensive meta-analysis and metaregression
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24472252
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24472252&amp;id=doi:10.1016%2Fj.jaac.2013.11.005&amp;issn=0890-8567&amp;isbn=&amp;volume=53&amp;issue=2&amp;spage=174&amp;pages=174-87&amp;date=2014&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Efficacy+and+safety+of+atomoxetine+in+children+and+adolescents+with+attention-deficit%2Fhyperactivity+disorder%3A+results+from+a+comprehensive+meta-analysis+and+metaregression.&amp;aulast=Schwartz&amp;pid=%3Cauthor%3ESchwartz+S%3C%2Fauthor%3E%3CAN%3E24472252%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0890856713008149/1-s2.0-S0890856713008149-main.pdf?_tid=174ac756-1674-11e5-828e-00000aab0f02&amp;acdnat=1434712536_10a6d1b1e5250c2222ef8dfb3ae40cc8
VL  - 53
ER  -
TY  - JOUR
AB  - **Background **
School tobacco policies (STPs) might prove to be a promising strategy to prevent smoking initiation among adolescents, as there is evidence that the school environment can influence young people to smoke. STPs are cheap, relatively easy to implement and have a wide reach, but it is not clear whether this approach is effective in preventing smoking uptake. 

**Objectives **
To assess the effectiveness of policies aiming to prevent smoking initiation among students by regulating smoking in schools. Search methods We searched seven electronic bibliographic databases, including the Cochrane Tobacco Addiction Group specialized register, MEDLINE, EMBASE, PsycINFO and ERIC. We also searched the grey literature and ongoing trials resources. The most recent search was performed in May 2014. Selection criteria We included cluster-randomised controlled trials (c-RCTs) in which primary and secondary schools were randomised to receive different levels of smoking policy or no intervention. Non-randomised controlled trials, interrupted time series and controlled before-after studies would also have been eligible. Cross-sectional studies were not formally included but we describe their findings and use them to generate hypotheses to inform future research. 

**Data collection and analysis **
We independently assessed studies for inclusion in the review, and present a narrative synthesis, as the studies are too limited in quality to undertake a formal meta-analysis. 

**Main results**
We found only one study which was eligible for inclusion in the review. It was judged to be at high risk of bias. The study compared two &#039;middle schools&#039; from two different regions in China. The experimental conditions included the introduction of a tobacco policy, environmental changes, and communication activities, while the control condition was no intervention. 

After a year&#039;s follow-up the study found no differences in smoking prevalence between intervention and control schools. We also described 24 observational studies, the results of which we considered for hypothesis generation. In these, policy exposure was mainly described using face-to-face interviews with school staff members, and the outcome evaluation was performed using self-administered questionnaires. Most studies reported no differences in students&#039; smoking prevalence between schools with formal STPs when compared with schools without policies. In the majority of studies in schools with highly enforced policies, smoking bans extended to outdoor spaces, involving teachers and including sanctions for transgressions, with assistance to quit for smokers plus support by prevention programmes, there was no significant difference in smoking prevalence when compared to schools adopting weaker or no policies. 

**Authors&#039; conclusions **
Despite a comprehensive literature search, and rigorous evaluation of studies, we found no evidence to support STPs. The absence of reliable evidence for the effectiveness of STPs is a concern in public health. We need well-designed randomised controlled trials or quasi-experimental studies to evaluate the effectiveness of school tobacco policies.
AD  - [Coppo, Alessandro; Buscemi, Daria] Avogadro Univ, Dept Translat Med, Novara, Italy. [Galanti, Maria Rosaria] Karolinska Inst, Div Publ Hlth Epidemiol, Stockholm, Sweden. [Giordano, Livia] AOU San Giovanni Battista Hosp, CPO Piemonte, Ctr Oncol Prevent, Turin, Italy. [Bremberg, Sven] Karolinska Inst, Dept Publ Hlth Sci, Stockholm, Sweden. [Faggiano, Fabrizio] Amedeo Avogadro Univ Eastern Piedmont, Dept Translat Med, Novara, Italy. Coppo, A (reprint author), Avogadro Univ, Dept Translat Med, Novara, Italy. alessandro.coppo@cpo.it
AN  - WOS:000347646000068
AU  - Coppo,
AU  - A.
AU  - Galanti,
AU  - M.
AU  - R.
AU  - Giordano,
AU  - L.
AU  - Buscemi,
AU  - D.
AU  - Bremberg,
AU  - S.
AU  - Faggiano,
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009990.pub2
J2  - Cochrane Database Syst Rev.
KW  - FRAMEWORK APPROACH ESFA CROSS-SECTIONAL DATA MULTILEVEL ANALYSIS ADOLESCENT SMOKING CIGARETTE-SMOKING TOBACCO-CONTROL STUDENTS SMOKING REDUCE SMOKING PERCEIVED ENFORCEMENT ELEMENTARY-SCHOOLS Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AY5YW Times Cited: 0 Cited Reference Count: 90 Coppo, Alessandro Galanti, Maria Rosaria Giordano, Livia Buscemi, Daria Bremberg, Sven Faggiano, Fabrizio WILEY-BLACKWELL HOBOKEN COCHRANE DB SYST REV
PY  - 2014
SP  - 38
T2  - Cochrane Database of Systematic Reviews
TI  - School policies for preventing smoking among young people
UR  - &lt;Go to ISI&gt;://WOS:000347646000068http://onlinelibrary.wiley.com/store/10.1002/14651858.CD009990.pub2/asset/CD009990.pdf?v=1&amp;t=ib7t8btt&amp;s=b6a68f8d39512b04162ccdd2705df0b89d585c18
ER  -
TY  - JOUR
AB  - **Aim:** 
To systematically review the efficacy of parenting interventions in improving the quality of the relationship between mothers and preterm infants. 

**Method:** 
Randomized or quasi-randomized controlled trials (RCT) of parenting interventions for mothers of preterm infants where mother-infant relationship quality outcomes were reported. Databases searched: The Cochrane Library, PubMed, CINAHL, PsycINFO and Web of Science. 

**Results:** 
Seventeen studies met the inclusion criteria, 14 with strong methodological quality. Eight parenting interventions were found to improve the quality of the mother preterm infant relationship. 

**Conclusions:** 
Heterogeneity of the interventions calls for an integrated new parenting program focusing on cue-based, responsive care from the mother to her preterm infant to improve the quality of the relationship for these mother preterm infant dyads. 

(C) 2014 Elsevier Inc. All rights reserved.
AD  - [Evans, Tracey; Whittingham, Koa; Boyd, Roslyn N.] Univ Queensland, Sch Med, Fac Hlth Sci, Queensland Cerebral Palsy &amp; Rehabil Res Ctr, Brisbane, Qld 4072, Australia. [Evans, Tracey; Whittingham, Koa] Univ Queensland, Fac Social &amp; Behav Sci, Sch Psychol, Brisbane, Qld 4072, Australia. [Evans, Tracey; Colditz, Paul] Royal Brisbane &amp; Womens Hosp, Perinatal Res Ctr, Brisbane, Qld, Australia. [Colditz, Paul] Univ Queensland, Clin Res Ctr, Royal Brisbane &amp; Womens Hosp, Brisbane, Qld, Australia. [Sanders, Matthew] Univ Queensland, Parenting &amp; Family Support Ctr, Brisbane, Qld 4072, Australia. Evans, T (reprint author), Univ Queensland, Perinatal Res Ctr, Royal Brisbane &amp; Womens Hosp, Level 6,Ned Hanlon Bldg, Herston, Qld 4029, Australia. t.evans3@uq.edu.au
AN  - WOS:000336186500001
AU  - Evans,
AU  - T.
AU  - Whittingham,
AU  - K.
AU  - Sanders,
AU  - M.
AU  - Colditz,
AU  - P.
AU  - Boyd,
AU  - R.
AU  - N.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.infbeh.2013.12.009
J2  - Infant Behav. Dev.
KW  - Mother-infant relationship Attachment Parenting intervention Preterm infant Prematurity NEONATAL INTENSIVE-CARE FAMILY-BASED INTERVENTION PREMATURE-INFANTS CONTROLLED-TRIAL GUIDED PARTICIPATION MENTAL-HEALTH FOLLOW-UP BIRTH ATTACHMENT OUTCOMES Psycholog
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AH5QS Times Cited: 2 Cited Reference Count: 59 Evans, Tracey Whittingham, Koa Sanders, Matthew Colditz, Paul Boyd, Roslyn N. Colditz, Paul/F-6772-2010; Boyd, Roslyn/A-4498-2011 Boyd, Roslyn/0000-0002-4919-5975 2 ELSEVIER SCIENCE INC NEW YORK INFANT BEHAV DEV
PY  - 2014
SP  - 131-154
T2  - Infant Behavior &amp; Development
TI  - Are parenting interventions effective in improving the relationship between mothers and their preterm infants?
UR  - &lt;Go to ISI&gt;://WOS:000336186500001http://ac.els-cdn.com/S0163638313001203/1-s2.0-S0163638313001203-main.pdf?_tid=b336b06e-1659-11e5-96fb-00000aacb35f&amp;acdnat=1434701202_c7048f33de93e114cefb08c73f9c8d57
VL  - 37
ER  -
TY  - JOUR
AB  - Smith, Waschbusch, Willoughby, and Evans (2000) reviewed a small treatment literature on ADHD in adolescents and concluded that methylphenidate stimulant medication was a well-established treatment and behavior therapy (BT) demonstrated preliminary efficacy.
 
This review extends and updates the findings of the prior one based on the previous 15 years of research. Studies published since 1999 were identified and coded using standard criteria and effect sizes were calculated where appropriate. Highlights of the last 15 years of research include an expansion of pharmacological treatment options and developmentally appropriate psychosocial treatment packages for adolescents with ADHD. 

Additionally, nonstimulant medications (e.g., atomoxetine) are now approved for the treatment of ADHD in adolescence. The review concludes that medication and BT produce a similar range of therapeutic effects on the symptoms of adolescents with ADHD. However, results suggest that BT may produce greater overall benefits on measures of impairment. 

There was no evidence that cognitive enhancement trainings, such as working memory training or neurofeedback improved the functioning of adolescents with ADHD. Whether to use medication, BT, or their combination to treat an adolescent with ADHD is complicated and we provide evidence-informed guidelines for treatment selection. 

The reviewed evidence does not support current American Academy of Pediatrics and American Academy of Child and Adolescent Psychiatry professional guidelines, which state that stimulant medication is the preferred treatment for adolescents with ADHD. Recommendations for assessment, practice guidelines, and future research are discussed. 

(C) 2014 Elsevier Ltd. All rights reserved.
AD  - [Sibley, Margaret H.; Kuriyan, Aparajita B.] Florida Int Univ, Miami, FL 33199 USA. [Evans, Steven W.] Ohio Univ, Athens, OH 45701 USA. [Waxmonsky, James G.] Penn State Univ, Milton S Hershey Med Ctr, Hershey, PA 17033 USA. [Smith, Bradley H.] Univ Houston, Houston, TX USA. Sibley, MH (reprint author), Florida Int Univ, Ctr Children &amp; Families, Dept Psychiat &amp; Behav Hlth, 11200 SW 8th St,AHC 1 Room 146, Miami, FL 33199 USA. msibley@fiu.edu
AN  - WOS:000335093400004
AU  - Sibley,
AU  - M.
AU  - H.
AU  - Kuriyan,
AU  - A.
AU  - B.
AU  - Evans,
AU  - S.
AU  - W.
AU  - Waxmonsky,
AU  - J.
AU  - G.
AU  - Smith,
AU  - B.
AU  - H.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2014.02.001
J2  - Clin. Psychol. Rev.
KW  - ADHD Adolescence Behavior therapy Stimulant medication ATTENTION-DEFICIT/HYPERACTIVITY DISORDER DEFICIT HYPERACTIVITY DISORDER RANDOMIZED CONTROLLED-TRIAL SUBSTANCE USE DISORDERS SALTS EXTENDED-RELEASE SUMMER TREATMENT PROGRAM MIDDLE SCHOOL STUDENTS DOU
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AG0GH Times Cited: 6 Cited Reference Count: 112 Sibley, Margaret H. Kuriyan, Aparajita B. Evans, Steven W. Waxmonsky, James G. Smith, Bradley H. 6 PERGAMON-ELSEVIER SCIENCE LTD OXFORD CLIN PSYCHOL REV
PY  - 2014
SP  - 218-232
T2  - Clinical Psychology Review
TI  - Pharmacological and psychosocial treatments for adolescents with ADHD: An updated systematic review of the literature
UR  - &lt;Go to ISI&gt;://WOS:000335093400004http://ac.els-cdn.com/S0272735814000488/1-s2.0-S0272735814000488-main.pdf?_tid=7240580a-1972-11e5-a3b3-00000aacb35d&amp;acdnat=1435041683_792061e60c20aee85d52a0a1ac8cdc86
VL  - 34
ER  -
TY  - JOUR
AB  - **Background:**
Drug use among youths is associated with negative health and social consequences. Even infrequent use increases the risk for serious adverse events by increasing risk-taking behaviors in intoxicated or impaired persons. 

**Purpose: **
To systematically review the benefits and harms of primary care-relevant interventions designed to prevent or reduce illicit drug use or the nonmedical use of prescription drugs among youths. Data Sources: PubMed, PsycINFO, and the Cochrane Central Register of Controlled Trials through 4 June 2013; MEDLINE through 31 August 2013; and manual searches of reference lists and gray literature. 

**Study Selection: **
Two investigators independently reviewed 2253 abstracts and 144 full-text articles. English-language trials of primary care-relevant behavioral interventions that reported drug use, health outcomes, or harms were included. 

**Data Extraction: **
One investigator abstracted data from good- and fair-quality trials into prespecified evidence tables, and a second investigator checked these data. 

**Data Synthesis: **
Six trials were included, 4 of which examined the effect of the intervention on a health or social outcome. One trial found no effect of the intervention on marijuana-related consequences or driving under the influence of marijuana; 3 trials generally found no reduction in depressed mood at 12 or 24 months. Four of the 5 trials assessing self-reported marijuana use found statistically significant differences favoring the intervention group participants (such as a between-group difference of 0.10 to 0.17 use occasions in the past month). Three trials also reported positive outcomes in nonmedical prescription drug use occasions. 

**Limitations: **
The body of evidence was small, and there were heterogeneous measures of outcomes of limited clinical applicability. Trials primarily included adolescents with little or no substance use.

**Conclusion: **
Evidence is inadequate on the benefits of primary care-relevant behavioral interventions in reducing self-reported illicit and pharmaceutical drug use among adolescents.
AD  - [Patnode, Carrie D.; O&#039;Connor, Elizabeth; Rowland, Maya; Burda, Brittany U.; Perdue, Leslie A.; Whitlock, Evelyn P.] Kaiser Permanente Northwest, Portland, OR USA. Patnode, CD (reprint author), Kaiser Permanente Ctr Hlth Res, 3800 North Interstate Ave, Portland, OR 97227 USA.
AN  - WOS:000336524400004
AU  - Patnode,
AU  - C.
AU  - D.
AU  - Connor,
AU  - E.
AU  - Rowland,
AU  - M.
AU  - Burda,
AU  - B.
AU  - U.
AU  - Perdue,
AU  - L.
AU  - A.
AU  - Whitlock,
AU  - E.
AU  - P.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.7326/M13-2064
J2  - Ann. Intern. Med.
KW  - MOTHER-DAUGHTER PROGRAM SUBSTANCE USE OUTCOMES GIRLS COMPUTER TRIAL ABUSE TEENS Medicine, General &amp; Internal
L1  - internal-pdf://0083036961/Patnode-2014-Primary Care Behavioral Intervent.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AI0GO Times Cited: 0 Cited Reference Count: 27 Patnode, Carrie D. O&#039;Connor, Elizabeth Rowland, Maya Burda, Brittany U. Perdue, Leslie A. Whitlock, Evelyn P. Agency for Healthcare Research and Quality Agency for Healthcare Research and Quality. AMER COLL PHYSICIANS PHILADELPHIA ANN INTERN MED
PY  - 2014
SP  - 612-U161
T2  - Annals of Internal Medicine
TI  - Primary Care Behavioral Interventions to Prevent or Reduce Illicit Drug Use and Nonmedical Pharmaceutical Use in Children and Adolescents: A Systematic Evidence Review for the US Preventive Services Task Force
UR  - &lt;Go to ISI&gt;://WOS:000336524400004http://annals.org/data/Journals/AIM/930096/0000605-201405060-00005.pdf
UR  - http://annals.org/data/journals/aim/930096/0000605-201405060-00005.pdf
VL  - 160
ER  -
TY  - JOUR
AB  - The purpose of this review was to better understand the impact of universal campaign interventions with a media component aimed at preventing child physical abuse (CPA). 

The review included 17 studies featuring 15 campaigns conducted from 1989 to 2011 in five countries. Seven studies used experimental designs, but most were quasi-experimental. 

CPA incidence was assessed in only three studies and decreased significantly in two. Studies also found significant reductions in relevant outcomes such as dysfunctional parenting, child problem behaviors and parental anger as well as increases in parental self-efficacy and knowledge of concepts and actions relevant to preventing child abuse. 

The following risk factors were most frequently targeted in campaigns: lack of knowledge regarding positive parenting techniques, parental impulsivity, the stigma of asking for help, inadequate social support and inappropriate expectations for a child&#039;s developmental stage. 

The evidence base for universal campaigns designed to prevent CPA remains inconclusive due to the limited availability of rigorous evaluations; however, Triple-P is a notable exception. 

Given the potential for such interventions to shift population norms relevant to CPA and reduce rates of CPA, there is a need to further develop and rigorously evaluate such campaigns.
AD  - [Poole, Mary Kathryn; Seal, David W.; Taylor, Catherine A.] Tulane Univ, Sch Publ Hlth &amp; Trop Med, Dept Global Community Hlth &amp; Behav Sci, New Orleans, LA 70112 USA. Taylor, CA (reprint author), Tulane Univ, Sch Publ Hlth &amp; Trop Med, Dept Global Community Hlth &amp; Behav Sci, New Orleans, LA 70112 USA. ctaylor5@tulane.edu
AN  - WOS:000336429800003
AU  - Poole,
AU  - M.
AU  - K.
AU  - Seal,
AU  - D.
AU  - W.
AU  - Taylor,
AU  - C.
AU  - A.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1093/her/cyu012
J2  - Health Educ. Res.
KW  - MASS-MEDIA CAMPAIGNS SHAKEN BABY SYNDROME CORPORAL PUNISHMENT TELEVISION SERIES RANDOMIZED-TRIAL FAMILY WELLNESS UNITED-STATES FOLLOW-UP MALTREATMENT HEALTH Education &amp; Educational Research Public, Environmental &amp; Occupational Health
L1  - internal-pdf://1320637293/Poole-2014-A systematic review of universal ca.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: AH9AD Times Cited: 0 Cited Reference Count: 63 Poole, Mary Kathryn Seal, David W. Taylor, Catherine A. OXFORD UNIV PRESS OXFORD HEALTH EDUC RES
PY  - 2014
SP  - 388-432
T2  - Health Education Research
TI  - A systematic review of universal campaigns targeting child physical abuse prevention
UR  - &lt;Go to ISI&gt;://WOS:000336429800003http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021196/pdf/cyu012.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021196/pdf/cyu012.pdf
VL  - 29
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
This is the first study to use meta-analysis as a scientific technique to provide an integrated analysis of the effectiveness of music intervention in cancer patients. 

**OBJECTIVES: **
The purpose of this study was, using the meta-analysis method, to present a summary of existing research and explore the effectiveness of music intervention in ameliorating anxiety, depression, pain, and fatigue in cancer patients. 

**METHODS: **
The present study collected quantitative study designs sought of music intervention for cancer patients published from 2002 to 2012. These studies were then cross-referenced using Medical Subject Headings for topics on music intervention and cancer patients. Outcome indicators were anxiety, depression, pain, and fatigue. The quality of the studies was evaluated using Cochrane Collaboration Guidelines. The effect size on outcome indicators used the formula devised by Hedges and Olkin (1985). 

**RESULTS: **
Results showed that music interventions were significantly effective in ameliorating anxiety (g = -0.553), depression (g = -0.510), pain (g = -0.656), and fatigue (g = -0.422) in cancer patients. Subgroup analyses revealed that age and who selected the music were major factors influencing the effect size on anxiety reduction. 

**CONCLUSIONS: **
Music interventions significantly ameliorate anxiety, depression, pain, and fatigue in cancer patients, especially adults. Music interventions were more effective in adults than in children or adolescents and more effective when patients, rather than researchers, chose the music. 

**IMPLICATIONS FOR PRACTICE: **
Our findings provide important information for future music-intervention planners to improve the design and processes that will benefit patients in such programs.
AD  - Tsai,Hsiu F. Author Affiliations: Graduate Institute of Nursing, College of Nursing, Taipei Medical University, (Mss Tsai and Chen, Drs Chung, Liao, and Chou); Department of Nursing, Taoyuan Armed Forces General Hospital, (Ms Chen); Department of Nursing, Hsin Sheng College of Medical Care and Management, Tauyuan (Ms Tsai); and School of Gerontology Health Management, College of Nursing, Taipei Medical University, Taiwan (Drs Chi and Chang).
AN  - 24662723
AU  - Tsai,
AU  - H.
AU  - F.
AU  - Chen,
AU  - Y.
AU  - R.
AU  - Chung,
AU  - M.
AU  - H.
AU  - Liao,
AU  - Y.
AU  - M.
AU  - Chi,
AU  - M.
AU  - J.
AU  - Chang,
AU  - C.
AU  - C.
AU  - Chou,
AU  - K.
AU  - R.
DA  - Nov-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/NCC.0000000000000116
DP  - Ovid Technologies
J2  - Cancer Nurs
L1  - internal-pdf://2247724833/Tsai-2014-Effectiveness of music intervention.pdf
LA  - English
N1  - Tsai, Hsiu F Chen, Ying R Chung, Min H Liao, Yuan M Chi, Mei J Chang, Chia C Chou, Kuei R
PY  - 2014
SP  - E35-50
T2  - Cancer Nursing
TI  - Effectiveness of music intervention in ameliorating cancer patients&#039; anxiety, depression, pain, and fatigue: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24662723 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24662723&amp;id=doi:10.1097%2FNCC.0000000000000116&amp;issn=0162-220X&amp;isbn=&amp;volume=37&amp;issue=6&amp;spage=E35&amp;pages=E35-50&amp;date=2014&amp;title=Cancer+Nursing&amp;atitle=Effectiveness+of+music+intervention+in+ameliorating+cancer+patients%27+anxiety%2C+depression%2C+pain%2C+and+fatigue%3A+a+meta-analysis.&amp;aulast=Tsai&amp;pid=%3Cauthor%3ETsai+HF%3C%2Fauthor%3E%3CAN%3E24662723%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://graphics.tx.ovid.com/ovftpdfs/FPDDNCJCMECLIN00/fs046/ovft/live/gv023/00002820/00002820-201411000-00014.pdf
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCDCDBALNL00/fs046/ovft/live/gv023/00002820/00002820-201411000-00014.pdf
VL  - 37
ER  -
TY  - JOUR
AB  - **BACKGROUND AND OBJECTIVES: **
Home visiting is 1 strategy to improve child health and parenting. Since implementation of home visiting trials 2 decades ago, US preterm births (&lt; 37 weeks) have risen by 20%. The objective of this study was to review evidence regarding home visiting and outcomes of preterm infants 

**METHODS: **
Searches of Medline, Cumulative Index to Nursing and Allied Health Literature, Cochrane Database of Systematic Reviews, Cochrane Controlled Trial Register, PsycINFO, and Embase were conducted. Criteria for inclusion were (1) cohort or controlled trial designs; (2) home-based, preventive services for infants at medical or social risk; and (3) outcomes reported for infants born preterm or low birth weight (&lt; 2500 g). Data from eligible reports were abstracted by 2 reviewers. Random effects meta-analysis was used to synthesize data for developmental and parent interaction measures. 

**RESULTS: **
Seventeen studies (15 controlled trials, 2 cohort studies) were reviewed. Five outcome domains were identified: infant development, parent-infant interaction, morbidity, abuse/neglect, and growth/nutrition. Six studies (n = 336) demonstrated a pooled standardized mean difference of 0.79 (95% confidence interval 0.57 to 1.02) in Home Observation for Measurement of the Environment Inventory scores at 1 year in the home-visited groups versus control. Evidence for other outcomes was limited. Methodological limitations were common. 

**CONCLUSIONS: **
Reviewed studies suggest that home visiting for preterm infants promotes improved parent-infant interaction. Further study of interventions targeting preterm infants within existing programs may strengthen the impact and cost benefits of home visiting in at-risk populations.
AD  - [Goyal, Neera K.] Cincinnati Childrens Hosp Med Ctr, Div Neonatol &amp; Pulm Biol, Cincinnati, OH 45229 USA. [Goyal, Neera K.] Cincinnati Childrens Hosp Med Ctr, Div Hosp Med, Cincinnati, OH 45229 USA. [Teeters, Angelique; Ammerman, Robert T.] Cincinnati Childrens Hosp Med Ctr, Div Behav Med &amp; Clin Psychol, Cincinnati, OH 45229 USA. [Goyal, Neera K.; Teeters, Angelique; Ammerman, Robert T.] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA. Goyal, NK (reprint author), Cincinnati Childrens Hosp Med Ctr, Dept Pediat, 3333 Burnet Ave,ML 7009, Cincinnati, OH 45229 USA. neera.goyal@cchmc.org
AN  - WOS:000325077800046
AU  - Goyal,
AU  - N.
AU  - K.
AU  - Teeters,
AU  - A.
AU  - Ammerman,
AU  - R.
AU  - T.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2013-0077
J2  - Pediatrics
KW  - home visiting preterm infants parent-child relationship development low birth weight LOW-BIRTH-WEIGHT VERMONT INTERVENTION PROGRAM PREMATURE-INFANTS RANDOMIZED-TRIAL FOLLOW-UP DEVELOPMENTAL INTERVENTION RISK INFANTS MOTHERS HEALTH DISCHARGE Pediatrics
L1  - internal-pdf://0803892834/Goyal-2013-Home Visiting and Outcomes of Prete.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 226ZX Times Cited: 5 Cited Reference Count: 54 Goyal, Neera K. Teeters, Angelique Ammerman, Robert T. Building Interdisciplinary Research Careers in Women&#039;s Health program; Office of Research on Women&#039;s Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development [5K12HD051953-07]; National Institute of Mental Health [R01MH087499]; National Institutes of Health (NIH) Dr Goyal&#039;s involvement in this project was supported by the Building Interdisciplinary Research Careers in Women&#039;s Health program, cofunded by the Office of Research on Women&#039;s Health and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, award 5K12HD051953-07. Dr Ammerman was supported by grant R01MH087499 from the National Institute of Mental Health. Funded by the National Institutes of Health (NIH). 5 AMER ACAD PEDIATRICS ELK GROVE VILLAGE PEDIATRICS
PY  - 2013
SP  - 502-516
T2  - Pediatrics
TI  - Home Visiting and Outcomes of Preterm Infants: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000325077800046http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876756/pdf/peds.2013-0077.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876756/pdf/peds.2013-0077.pdf
VL  - 132
ER  -
TY  - JOUR
AB  - High-stakes tests have played an increasingly important role in how student achievement and school effectiveness are measured. 

Test anxiety has risen with the use of tests in educational decision making. Students with high test anxiety perform poorly on tests when compared to students with low test anxiety. 

School psychologists can play an important role as experts both in tests and measurement and mental health in providing consultation and treatment for students with test anxiety. 

This article describes the results of a systematic literature review of the last 10 years of test-anxiety interventions. 

Results indicate that there are few studies that have examined test-anxiety interventions with elementary and secondary school students. 

However, techniques including biofeedback, behavior therapy, cognitive behavioral therapy, priming competency, and mixed approaches have demonstrated promising results. Suggestions are made for school psychologists for the delivery of evidenced-based test anxiety interventions.
AD  - [von der Embse, Nathaniel] E Carolina Univ, Dept Psychol, Greenville, NC 27858 USA. [Barterian, Justin] Michigan State Univ, E Lansing, MI 48824 USA. [Segool, Natasha] Univ Hartford, Hartford, CT 06117 USA. von der Embse, N (reprint author), E Carolina Univ, Dept Psychol, Greenville, NC 27858 USA. vonderembsen@ecu.edu
AN  - WOS:000312558100005
AU  - von
AU  - der
AU  - Embse,
AU  - N.
AU  - Barterian,
AU  - J.
AU  - Segool,
AU  - N.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/pits.21660
J2  - Psychol. Schools
KW  - TEST-PERFORMANCE STUDENTS METAANALYSIS ELEMENTARY INVENTORY DISORDER GENDER SCORES SCALE TAICA Psychology, Educational
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 057JA Times Cited: 5 Cited Reference Count: 41 von der Embse, Nathaniel Barterian, Justin Segool, Natasha 5 WILEY-BLACKWELL HOBOKEN PSYCHOL SCHOOLS
PY  - 2013
SP  - 57-71
T2  - Psychology in the Schools
TI  - Test Anxiety Interventions for Children and Adolescents: A Systematic Review of Treatment Studies from 2000-2010
UR  - &lt;Go to ISI&gt;://WOS:000312558100005http://onlinelibrary.wiley.com/store/10.1002/pits.21660/asset/pits21660.pdf?v=1&amp;t=ib3kbsnk&amp;s=cceea167c1aec776c93580289d216988daf64619
VL  - 50
ER  -
TY  - JOUR
AB  - **Objective: **
To systematically review the efficacy and tolerability data of antipsychotics in children and adolescents with schizophrenia. Materials and 

**Methods: **
Pubmed, Google scholar and Psych Info were searched to identify studies published in peer-reviewed English language journals. All studies evaluating the efficacy of antipsychotics in children and adolescents with schizophrenia and having 3 or more participants were included. Of the studies identified, only randomized controlled trials were included in the meta-analysis. Data was analysed using effect size calculation as per Cohen&#039;s d. Fifty published studies were identified which reported use of antipsychotics in children and adolescents with schizophrenia. Of these, 15 randomized controlled studies were included in meta-analysis. 

**Results: **
Evidence suggests that both first generation antipsychotics (FGA) and second generation antipsychotics (SGAs) are better than placebo (effect size [ES] 2.948, confidence interval [CI] 1.368 to 4.528, sample size 31; and ES 0.454, CI 0.414 to 0.542, sample size 1308 respectively). 

However, FGAs seemed to be inferior to SGAs (ES -0.363, CI -0.562 to -0.163, sample size of 243) and clozapine is superior to all other antipsychotics (ES 0.848, CI 0.748 to 0.948, and sample size 85) in treatment of schizophrenia in children and adolescents. The extrapyramidal side effects are more common with FGAs while metabolic adverse effects are more common with SGAs. 

**Conclusion: **
FGAs and SGAs are effective in the treatment of children and adolescents with schizophrenia. Clozapine apparently is the most effective antipsychotic in this condition.
AD  - (Sarkar, Grover) Department of Psychiatry, Institute of Medical Education and Research, Chandigarh, IndiaS. Grover, Department of Psychiatry, Institute of Medical Education and Research, Chandigarh, India. E-mail: drsandeepg2002@yahoo.com
AN  - 369880980
AU  - Sarkar,
AU  - S.
AU  - Grover,
AU  - S.
DA  - September-October
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4103/0253-7613.117720
DP  - Ovid Technologies
KW  - Adolescents
KW  - antipsychotics
KW  - children
KW  - schizophrenia
KW  - acne/si [Side Effect]
KW  - adolescent disease/dt [Drug Therapy]
KW  - agitation
KW  - akathisia/si [Side Effect]
KW  - allergy/si [Side Effect]
KW  - anxiety
KW  - anxiety disorder/si [Side Effect]
KW  - attention disturbance/si [Side Effect]
KW  - blurred vision/si [Side Effect]
KW  - Brief Psychiatric Rating Scale
KW  - childhood disease/dt [Drug Therapy]
KW  - Clinical Global Impression scale
KW  - constipation/si [Side Effect]
KW  - decreased appetite/si [Side Effect]
KW  - depression/si [Side Effect]
KW  - dizziness/si [Side Effect]
KW  - drowsiness/si [Side Effect]
KW  - drug efficacy
KW  - drug tolerability
KW  - dyslipidemia/si [Side Effect]
KW  - enuresis/si [Side Effect]
KW  - extrapyramidal symptom/si [Side Effect]
KW  - fatigue/si [Side Effect]
KW  - galactorrhea/si [Side Effect]
KW  - glucose intolerance/si [Side Effect]
KW  - headache/si [Side Effect]
KW  - human
KW  - hypersalivation/si [Side Effect]
KW  - hypertension/si [Side Effect]
KW  - increased appetite/si [Side Effect]
KW  - insomnia/si [Side Effect]
KW  - irritability
KW  - low drug dose
KW  - lymphocyte count
KW  - meta analysis
KW  - muscle rigidity/si [Side Effect]
KW  - nausea/si [Side Effect]
KW  - nose obstruction/si [Side Effect]
KW  - orthostatic hypotension/si [Side Effect]
KW  - parkinsonism/si [Side Effect]
KW  - Positive and Negative Syndrome Scale
KW  - randomized controlled trial (topic)
KW  - restlessness/si [Side Effect]
KW  - review
KW  - salivation
KW  - schizophrenia/dt [Drug Therapy]
KW  - sedation
KW  - seizure/si [Side Effect]
KW  - side effect/si [Side Effect]
KW  - sleep disorder/si [Side Effect]
KW  - sore throat/si [Side Effect]
KW  - systematic review
KW  - tachycardia/si [Side Effect]
KW  - tremor/si [Side Effect]
KW  - vomiting/si [Side Effect]
KW  - weight gain
KW  - amisulpride/ae [Adverse Drug Reaction]
KW  - amisulpride/dt [Drug Therapy]
KW  - aripiprazole/ae [Adverse Drug Reaction]
KW  - aripiprazole/ct [Clinical Trial]
KW  - aripiprazole/dt [Drug Therapy]
KW  - clozapine/ae [Adverse Drug Reaction]
KW  - clozapine/ct [Clinical Trial]
KW  - clozapine/cm [Drug Comparison]
KW  - clozapine/dt [Drug Therapy]
KW  - fluphenazine/ae [Adverse Drug Reaction]
KW  - fluphenazine/ct [Clinical Trial]
KW  - fluphenazine/cm [Drug Comparison]
KW  - fluphenazine/dt [Drug Therapy]
KW  - haloperidol/ae [Adverse Drug Reaction]
KW  - haloperidol/ct [Clinical Trial]
KW  - haloperidol/cm [Drug Comparison]
KW  - haloperidol/dt [Drug Therapy]
KW  - loxapine/ae [Adverse Drug Reaction]
KW  - loxapine/dt [Drug Therapy]
KW  - molindone/ae [Adverse Drug Reaction]
KW  - molindone/ct [Clinical Trial]
KW  - molindone/cm [Drug Comparison]
KW  - molindone/dt [Drug Therapy]
KW  - neuroleptic agent/ct [Clinical Trial]
KW  - neuroleptic agent/dt [Drug Therapy]
KW  - olanzapine/ae [Adverse Drug Reaction]
KW  - olanzapine/ct [Clinical Trial]
KW  - olanzapine/cm [Drug Comparison]
KW  - olanzapine/dt [Drug Therapy]
KW  - paliperidone/ae [Adverse Drug Reaction]
KW  - paliperidone/ct [Clinical Trial]
KW  - paliperidone/dt [Drug Therapy]
KW  - quetiapine/ae [Adverse Drug Reaction]
KW  - quetiapine/ct [Clinical Trial]
KW  - quetiapine/dt [Drug Therapy]
KW  - risperidone/ae [Adverse Drug Reaction]
KW  - risperidone/ct [Clinical Trial]
KW  - risperidone/cm [Drug Comparison]
KW  - risperidone/dt [Drug Therapy]
KW  - thioridazine/ae [Adverse Drug Reaction]
KW  - thioridazine/dt [Drug Therapy]
KW  - tiotixene/ae [Adverse Drug Reaction]
KW  - tiotixene/dt [Drug Therapy]
KW  - ziprasidone/dt [Drug Therapy]
L1  - internal-pdf://1641683287/Sarkar-2013-Antipsychotics in children and ado.pdf
LA  - English
M3  - Review
N1  - Supplement.
PY  - 2013
SP  - 439-446
T2  - Indian Journal of Pharmacology
TI  - Antipsychotics in children and adolescents with schizophrenia: A systematic review and meta-analysis
UR  - http://www.ijp-online.com/
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emexb&amp;AN=369880980
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:24130376&amp;id=doi:10.4103%2F0253-7613.117720&amp;issn=0253-7613&amp;isbn=&amp;volume=45&amp;issue=5&amp;spage=439&amp;pages=439-446&amp;date=2013&amp;title=Indian+Journal+of+Pharmacology&amp;atitle=Antipsychotics+in+children+and+adolescents+with+schizophrenia%3A+A+systematic+review+and+meta-analysis&amp;aulast=Sarkar&amp;pid=%3Cauthor%3ESarkar+S.%3C%2Fauthor%3E%3CAN%3E369880980%3C%2FAN%3E%3CDT%3EReview%3C%2FDT%3E
UR  - http://www.ijp-online.com/article.asp?issn=0253-7613;year=2013;volume=45;issue=5;spage=439;epage=446;aulast=Sarkar
VL  - 45
ER  -
TY  - JOUR
AB  - **Background:** 
Schizophrenia often presents in adolescence, but current treatment guidelines are based largely on studies of adults with psychosis. Over the past decade, the number of studies on treatment of adolescent-onset psychosis has increased. The current systematic review collates and critiques evidence obtained on the use of various atypical antipsychotic medications for adolescents with psychosis.

**Objectives:** 
To investigate the effects of atypical antipsychotic medications in adolescents with psychosis. We reviewed in separate analyses various comparisons of atypical antipsychotic medications with placebo or a typical antipsychotic medication or another atypical antipsychotic medication or the same atypical antipsychotic medication but at a lower dose.

**Search methods:** 
We searched the Cochrane Schizophrenia Group Register (October 2011), which is based on regular searches of BIOSIS, CENTRAL, CINAHL, EMBASE, MEDLINE and PsycINFO. We inspected references of all identified studies and contacted study authors and relevant pharmaceutical companies to ask for more information.

**Selection criteria:** 
We included all relevant randomised controlled trials (RCTs) that compared atypical antipsychotic medication with placebo or another pharmacological intervention or with psychosocial interventions, standard psychiatric treatment or no intervention in children and young people aged 13 to 18 years with a diagnosis of schizophrenia, schizoaffective disorder, acute and transient psychoses or unspecified psychosis. We included studies published in English and in other languages that were available in standardised databases.

**Data collection and analysis:**
Review authors AK and SSD selected the studies, rated the quality of the studies and performed data extraction. For dichotomous data, we estimated risk ratios (RRs) with 95% confidence intervals (CIs) using a fixed-effect model. When possible, for binary data presented in the &#039;Summary of findings&#039; table, we calculated illustrative comparative risks. We summated continuous data using the mean difference (MD). Risk of bias was assessed for included studies.

**Main results:** 
We included 13 RCTs, with a total of 1112 participants. We found no data on service utilisation, economic outcomes, behaviour or cognitive response. Trials were classified into the following groups.1. Atypical antipsychotics versus placebo Only two studies compared one atypical antipsychotic medication with placebo. In one study, the number of non-responders treated with olanzapine was not different from the number treated with placebo (1 RCT, n = 107, RR 0.84, 95% CI 0.65 to 1.10); however, significantly more (57% vs 32%) people left the study early (1 RCT, n = 107, RR 0.56, 95% CI 0.36 to 0.87) from the placebo group compared with the olanzapine group. With regard to adverse effects, young people treated with aripiprazole had significantly lower serum cholesterol compared with those given placebo (1 RCT, n = 302, RR 3.77, 95% CI 1.88 to 7.58).2. Atypical antipsychotics versus typical antipsychotics When the findings of all five trials comparing atypical antipsychotic medications with a typical antipsychotic medication were collated, no difference in the mean end point Brief Psychiatric Rating Scale (BPRS) score was noted between the two arms (5 RCTs, n = 236, MD -1.08, 95% CI -3.08 to 0.93). With regard to adverse effects, the mean end&nbsp;point serum prolactin concentration was much higher than the reference range for treatment with risperidone, olanzapine and molindone in one of the studies. However, fewer adolescents who were receiving atypical antipsychotic medications left the study because of adverse effects (3 RCTs, n = 187, RR 0.65, 95% CI 0.36 to 1.15) or for any reason (3 RCTs, n = 187, RR 0.62, 95% CI 0.39 to 0.97).3. One atypical antipsychotic versus another atypical antipsychotic The mean end point BPRS score was not significantly different for people who received risperidone compared with those who received olanzapine; however, the above data were highly skewed. Overall no difference was noted in the numbe f people leaving the studies early because of any adverse effects between each study arm in the three studies comparing olanzapine and risperidone (3 RCTs, n = 130, RR 1.15, 95% CI 0.44 to 3.04). Specific adverse events were not reported uniformly across the six different studies included in this section of the review; therefore it was difficult to do a head-to-head comparison of adverse events for different atypical antipsychotic medications.4. Lower-dose atypical antipsychotic versus standard/higher-dose atypical antipsychotic Three studies reported comparisons of lower doses of the atypical antipsychotic medication with standard/higher doses of the same medication. One study reported better symptom reduction with a standard dose of risperidone as compared with a low dose (1 RCT, n = 257, RR -8.00, 95% CI -13.75 to -2.25). In another study, no difference was reported in the number of participants not achieving remission between the group receiving 10 mg/d and those who received 30 mg/d of aripiprazole (1 RCT, n = 196, RR 0.84, 95% CI 0.48 to 1.48). Similarly in the other study, authors reported no statistically significant difference in clinical response between the two groups receiving lower-dose (80 mg/d) and higher-dose (160 mg/d) ziprasidone, as reflected by the mean end point BPRS score (1 RCT, n = 17, MD -4.40, 95% CI -19.20 to 10.40).

**Authors&#039; conclusions:** 
No convincing evidence suggests that atypical antipsychotic medications are superior to typical medications for the treatment of adolescents with psychosis. However, atypical antipsychotic medications may be more acceptable to young people because fewer symptomatic adverse effects are seen in the short term. Little evidence is available to support the superiority of one atypical antipsychotic medication over another, but side effect profiles are different for different medications. Treatment with olanzapine, risperidone and clozapine is often associated with weight gain. Aripiprazole is not associated with increased prolactin or with dyslipidaemia. Adolescents may respond better to standard-dose as opposed to lower-dose risperidone, but for aripiprazole and ziprasidone, lower doses may be equally effective. Future trials should ensure uniform ways of reporting.
AN  - CD009582
AU  - Kumar,
AU  - A.
AU  - Datta,
AU  - S.
AU  - S.
AU  - Wright,
AU  - S.
AU  - D.
AU  - Furtado,
AU  - V.
AU  - A.
AU  - Russell,
AU  - P.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009582.pub2.
KW  - Antipsychotic Agents [adverse effects] [therapeutic use]
KW  - Aripiprazole
KW  - Benzodiazepines [adverse effects] [therapeutic use]
KW  - Molindone [adverse effects] [therapeutic use]
KW  - Piperazines [adverse effects] [therapeutic use]
KW  - Psychotic Disorders [drug therapy]
KW  - Quinolones [adverse effects] [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Risperidone [adverse effects] [therapeutic use]
KW  - Schizophrenia [drug therapy]
KW  - Adolescent[checkword]
KW  - Humans[checkword]
KW  - Schiz
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Atypical antipsychotics for psychosis in adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009582.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009582.pub2/asset/CD009582.pdf?v=1&amp;t=iw7ivj96&amp;s=51ed8883d5214e312c7baefa90248c2d0aba0761
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
To assess the effectiveness of interventions targeting traumatic stress among children exposed to nonrelational traumatic events (eg, accidents, natural disasters, war). 

**METHODS: **
We assessed research on psychological and pharmacological therapy as part of an Agency for Healthcare Research and Quality-commissioned comparative effectiveness review. We conducted focused searches of Medline, Cochrane Library, Embase, PsycINFO, Cumulative Index to Nursing and Allied Health Literature, International Pharmaceutical Abstracts, and Web of Science. Two trained reviewers independently selected, extracted data from, and rated the risk of bias of relevant trials and systematic reviews. We used qualitative rather than quantitative analysis methods because of statistical heterogeneity, insufficient numbers of similar studies, and variation in outcome reporting. 

**RESULTS: **
We found a total of 21 trials and 1 cohort study of medium or low risk of bias from our review of 6647 unduplicated abstracts. We generally did not find studies that attempted to replicate findings of effective interventions. In the short term, no pharmacotherapy intervention demonstrated efficacy, and only a few psychological treatments (each with elements of cognitive behavioral therapy) showed benefit. The body of evidence provides little insight into how interventions to treat children exposed to trauma might influence healthy long-term development. 

**CONCLUSIONS: **
Our findings serve as a call to action: Psychotherapeutic intervention may be beneficial relative to no treatment in children exposed to traumatic events. Definitive guidance, however, requires far more research on the comparative effectiveness of interventions targeting children exposed to nonrelational traumatic events. 

Pediatrics 2013;131:526-539
AD  - [Forman-Hoffman, Valerie L.; Viswanathan, Meera] RTI Int, Res Triangle Pk, NC 27709 USA. [Zolotor, Adam J.] Univ N Carolina, Sch Med, Dept Family Med, Chapel Hill, NC USA. [McKeeman, Joni L.; Blanco, Roberto] Univ N Carolina, Sch Med, Dept Psychiat, Chapel Hill, NC USA. [Knauer, Stefanie R.; Lloyd, Stacey W.] Univ N Carolina, Cecil G Sheps Ctr Hlth Serv Res, Chapel Hill, NC USA. [Fraser, Jenifer Goldman] Boston Med Ctr, Div Dev &amp; Behav Pediat, Boston, MA USA. Forman-Hoffman, VL (reprint author), RTI Int, 3040 Cornwallis Rd, Res Triangle Pk, NC 27709 USA. vhoffman@rti.org
AN  - WOS:000315587400057
AU  - Forman-Hoffman,
AU  - V.
AU  - L.
AU  - Zolotor,
AU  - A.
AU  - J.
AU  - McKeeman,
AU  - J.
AU  - L.
AU  - Blanco,
AU  - R.
AU  - Knauer,
AU  - S.
AU  - R.
AU  - Lloyd,
AU  - S.
AU  - W.
AU  - Fraser,
AU  - J.
AU  - G.
AU  - Viswanathan,
AU  - M.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2012-3846
J2  - Pediatrics
KW  - trauma posttraumatic stress disorder comparative effectiveness research intervention studies child adolescent RANDOMIZED CONTROLLED-TRIAL MENTAL-HEALTH INTERVENTION POSTTRAUMATIC-STRESS-DISORDER SCHOOL-BASED INTERVENTION POLITICAL VIOLENCE DOUBLE-BLIND
L1  - internal-pdf://0139789369/Forman-Hoffman-2013-Comparative Effectiveness.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 098ZI Times Cited: 1 Cited Reference Count: 38 Forman-Hoffman, Valerie L. Zolotor, Adam J. McKeeman, Joni L. Blanco, Roberto Knauer, Stefanie R. Lloyd, Stacey W. Fraser, Jenifer Goldman Viswanathan, Meera Agency for Healthcare Research and Quality [290-200-10056-I] All phases of this study were supported by Agency for Healthcare Research and Quality contract 290-200-10056-I. 1 AMER ACAD PEDIATRICS ELK GROVE VILLAGE PEDIATRICS
PY  - 2013
SP  - 526-539
T2  - Pediatrics
TI  - Comparative Effectiveness of Interventions for Children Exposed to Nonrelational Traumatic Events
UR  - &lt;Go to ISI&gt;://WOS:000315587400057http://pediatrics.aappublications.org/content/131/3/526.full.pdf
UR  - http://pediatrics.aappublications.org/content/pediatrics/131/3/526.full.pdf
VL  - 131
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To determine whether massage could help preterm infants improve weight gain, discharge from the hospital earlier, and promote the neurobehavioral development, a meta-analysis was conducted. 

**STUDY DESIGN: **
MEDLINE, Embase, CINAHL, Dissertation Abstracts, and the Cochrane Library were searched up to January 2012. There were no language restrictions. 

**RESULTS: **
In all, 611 articles were retrieved and 17 studies were eligible. Massage intervention improved daily weight gain by 5.32 g (95% confidence interval [CI] 4.15, 6.49, p &lt; 0.00001) and reduced length of stay by 4.41 days (95% CI 2.81, 6.02, p &lt; 0.00001). No significant differences yielded on the scores of Neonatal Behavioral Assessment Scale. 

**CONCLUSION: **
Massage therapy may be a safe and cost-effective practice to improve weight gain and decrease the hospital stay of clinically stable preterm infants. However, the association between massage and neurobehavioral development is still elusive. 
Future investigations with a larger sample size and strict protocol are required to confirm the effects of massage on the preterm infants.

Copyright Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
AD  - Wang,Li. Neonatal Diagnosis and Treatment Center, Children&#039;s Hospital of Chongqing Medical University, Chongqing, P. R. China.
AN  - 23322391
AU  - Wang,
AU  - L.
AU  - He,
AU  - J.
AU  - L.
AU  - Zhang,
AU  - X.
AU  - H.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1055/s-0032-1332801
DP  - Ovid Technologies
J2  - Am J Perinatol
KW  - *Child Development Humans Infant, Newborn *Infant, Premature/ph [Physiology] Infant, Premature/px [Psychology] *Length of Stay Massage/px [Psychology] *Massage *Weight Gain
LA  - English
M3  - Meta-Analysis
N1  - Wang, Li He, Jun Li Zhang, Xian Hong
PY  - 2013
SP  - 731-8
T2  - American Journal of Perinatology
TI  - The efficacy of massage on preterm infants: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23322391 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23322391&amp;id=doi:10.1055%2Fs-0032-1332801&amp;issn=0735-1631&amp;isbn=&amp;volume=30&amp;issue=9&amp;spage=731&amp;pages=731-8&amp;date=2013&amp;title=American+Journal+of+Perinatology&amp;atitle=The+efficacy+of+massage+on+preterm+infants%3A+a+meta-analysis.&amp;aulast=Wang&amp;pid=%3Cauthor%3EWang+L%3C%2Fauthor%3E%3CAN%3E23322391%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttps://www.thieme-connect.com/DOI/DOI?10.1055/s-0032-1332801https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0032-1332801.pdf
UR  - https://www.thieme-connect.com/DOI/DOI?10.1055/s-0032-1332801
VL  - 30
ER  -
TY  - JOUR
AB  - **Background **
Young children with autism spectrum disorders (ASD) have impairments in the areas of communication and social interaction and often display repetitive or non-compliant behaviour. This early pattern of difficulties is a challenge for parents. Therefore, approaches that help parents develop strategies for interaction and management of behaviour are an obvious route for early intervention in ASD. This review updates a Cochrane review first published in 2002 but is based on a new protocol. 

**Objectives **
To assess the effectiveness of parent-mediated early interventions in terms of the benefits for both children with ASD and their parents and to explore some potential moderators of treatment effect. 

**Search methods **
We searched a range of psychological, educational and biomedical databases including CENTRAL, MEDLINE, Embase, PsycINFO and ERIC in August 2012. As this is an update of a previous review, we limited the search to the period following the original searches in 2002. Bibliographies and reference lists of key articles were searched, field experts were contacted and key journals were handsearched. 

**Selection criteria **
We included only randomised controlled trials of early intervention for children with ASD. The interventions in the experimental condition were mediated by parents; the control conditions included no treatment, treatment as usual, waiting list, alternative child-centred intervention not mediated by parents, or alternative parent-mediated intervention of hypothesised lesser effect than the experimental condition. 

**Data collection and analysis **
Two review authors (HM and IPO) independently screened articles identified in the search and decided which articles should be retrieved in full. For each included study, two review authors (IPO and EH) extracted and recorded data, using a piloted data collection form. Two review authors (IPO and HM) assessed the risk of bias in each study. We performed data synthesis and analysis using The Cochrane Collaboration&#039;s Review Manager 5.1 software. 

**Main results **
The review includes 17 studies from six countries (USA, UK, Australia, Canada, Thailand and China), which recruited 919 children with ASD. Not all 17 studies could be compared directly or combined in meta-analyses due to differences in the theoretical basis underpinning interventions, the duration and intensity of interventions, and the outcome measurement tools used. Data from subsets of 10 studies that evaluated interventions to enhance parent interaction style and thereby facilitate children&#039;s communication were included in meta-analyses. The largest meta-analysis combined data from 316 participants in six studies and the smallest combined data from 55 participants in two studies. Findings from the remaining seven studies were reported narratively. High risk of bias was evident in the studies in relation to allocation concealment and incomplete outcome data; blinding of participants was not possible. Overall, we did not find statistical evidence of gains from parent-mediated approaches in most of the primary outcomes assessed (most aspects of language and communication -whether directly assessed or reported; frequency of child initiations in observed parent-child interaction; child adaptive behaviour; parents&#039; stress), with findings largely inconclusive and inconsistent across studies. However, the evidence for positive change in patterns of parent-child interaction was strong and statistically significant (shared attention: standardised mean difference (SMD) 0.41; 95% confidence interval (CI) 0.14 to 0.68, P value &lt; 0.05; parent synchrony: SMD 0.90; 95% CI 0.56 to 1.23, P value &lt; 0.05). Furthermore, there is some evidence suggestive of improvement in child language comprehension, reported by parents (vocabulary comprehension: mean difference (MD 36.26; 95% CI 1.31 to 71.20, P value &lt; 0.05). In addition, there was evidence suggesting a reduction in the severity of children&#039;s autism characteristics (SMD -0.30, 95% CI -0.52 to -0.08, P value &lt; 0.05). However, this evidence of change in children&#039;s skills and difficulties as a consequence of parent-mediated intervention is uncertain, with small effect sizes and wide CIs, and the conclusions are likely to change with future publication of high-quality RCTs. 

**Authors&#039; conclusions** 
The review finds some evidence for the effectiveness of parent-mediated interventions, most particularly in proximal indicators within parent-child interaction, but also in more distal indicators of child language comprehension and reduction in autism severity. Evidence of whether such interventions may reduce parent stress is inconclusive. The review reinforces the need for attention to be given to early intervention service models that enable parents to contribute skilfully to the treatment of their child with autism. However, practitioners supporting parent-mediated intervention require to monitor levels of parent stress. The ability to draw conclusions from studies would be improved by researchers adopting a common set of outcome measures as the quality of the current evidence is low.
AD  - [Oono, Inalegwu P.; McConachie, Helen] Newcastle Univ, Inst Hlth &amp; Soc, Newcastle Upon Tyne NE1 4LP, Tyne &amp; Wear, England. [Honey, Emma J.] Northumberland Tyne &amp; Wear NHS Fdn Trust, Complex Neurodev Disorders Serv, Newcastle Upon Tyne, Tyne &amp; Wear, England. McConachie, H (reprint author), Newcastle Univ, Inst Hlth &amp; Soc, Sir James Spence Inst, Victoria Rd, Newcastle Upon Tyne NE1 4LP, Tyne &amp; Wear, England. h.r.mcconachie@newcastle.ac.uk
AN  - WOS:000320654500034
AU  - Oono,
AU  - I.
AU  - P.
AU  - J.
AU  - Honey,
AU  - E.
AU  - J.
AU  - McConachie,
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009774.pub2
J2  - Cochrane Database Syst Rev.
KW  - RANDOMIZED CONTROLLED-TRIAL HOME-BASED INTERVENTION INTENSIVE BEHAVIORAL TREATMENT STONES TRIPLE P DEVELOPMENTAL DELAY JOINT ATTENTION COMPREHENSIVE TREATMENTS TRAINING INTERVENTION PRESCHOOL-CHILDREN PROGRAM Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 167SK Times Cited: 4 Cited Reference Count: 81 Oono, Inalegwu P. Honey, Emma J. McConachie, Helen The Nuffield Foundation, UK External sourcesThe Nuffield Foundation, UK. 4 WILEY-BLACKWELL HOBOKEN COCHRANE DB SYST REV
PY  - 2013
SP  - 101
T2  - Cochrane Database of Systematic Reviews
TI  - Parent-mediated early intervention for young children with autism spectrum disorders (ASD)
UR  - &lt;Go to ISI&gt;://WOS:000320654500034http://onlinelibrary.wiley.com/store/10.1002/14651858.CD009774.pub2/asset/CD009774.pdf?v=1&amp;t=ib7ucmte&amp;s=6bef2ad3fe0c2e67952f6fbcde987c27dd24664b
ER  -
TY  - JOUR
AB  - **Background:** 
Restorative justice is &quot;a process whereby parties with a stake in a specific offence resolve collectively how to deal with the aftermath of the offence and its implications for the future&quot; (Marshall 2003). Despite the increasing use of restorative justice programmes as an alternative to court proceedings, no systematic review has been undertaken of the available evidence on the effectiveness of these programmes with young offenders. Recidivism in young offenders is a particularly worrying problem, as recent surveys have indicated the frequency of re-offences for young offenders has ranged from 40.2% in 2000 to 37.8% in 2007 (Ministry of Justice 2009).

**Objectives:** 
To evaluate the effects of restorative justice conferencing programmes for reducing recidivism in young offenders.

**Search methods:** 
We searched the following databases up to May 2012: CENTRAL, 2012 Issue 5, MEDLINE (1978 to current), Bibliography of Nordic Criminology (1999 to current), Index to Theses (1716 to current), PsycINFO (1887 to current), Social Sciences Citation Index (1970 to current), Sociological Abstracts (1952 to current), Social Care Online (1985 to current), Restorative Justice Online (1975 to current), Scopus (1823 to current), Science Direct (1823 to current), LILACS (1982 to current), ERIC (1966 to current), Restorative Justice Online (4 May 2012), WorldCat (9 May 2012), ClinicalTrials.gov (19 May 2012) and ICTRP (19 May 2012). ASSIA, National Criminal Justice Reference Service and Social Services Abstracts were searched up to May 2011. Relevant bibliographies, conference programmes and journals were also searched.

**Selection criteria:**
Randomised controlled trials (RCTs) or quasi-RCTs of restorative justice conferencing versus management as usual, in young offenders.

**Data collection and analysis:** 
Two authors independently assessed the risk of bias of included trials and extracted the data. Where necessary, original investigators were contacted to obtain missing information.

**Main results:** 
Four trials including a total of 1447 young offenders were included in the review. Results failed to find a significant effect for restorative justice conferencing over normal court procedures for any of the main analyses, including number re-arrested (odds ratio (OR) 1.00, 95% confidence interval (CI) 0.59 to 1.71; P = 0.99), monthly rate of reoffending (standardised mean difference (SMD) -0.06, 95% CI -0.28 to 0.16; P = 0.61), young person?s remorse following conference (OR 1.73, 95% CI 0.97 to 3.10; P = 0.06), young person&#039;s recognition of wrongdoing following conference (OR 1.97, 95% CI 0.81 to 4.80; P = 0.14), young person&#039;s self-perception following conference (OR 0.95, 95% CI 0.55 to 1.63; P = 0.85), young person&#039;s satisfaction following conference (OR 0.42, 95% CI 0.04 to 4.07; P = 0.45) and victim&#039;s satisfaction following conference (OR 4.05, 95% CI 0.56 to 29.04; P = 0.16). A small number of sensitivity analyses did indicate significant effects, although all are to be interpreted with caution.

**Authors&#039; conclusions:** 
There is currently a lack of high quality evidence regarding the effectiveness of restorative justice conferencing for young offenders. Caution is urged in interpreting the results of this review considering the small number of included studies, subsequent low power and high risk of bias. The effects may potentially be more evident for victims than offenders. The need for further research in this area is highlighted.
AN  - CD008898
AU  - Livingstone,
AU  - N.
AU  - Macdonald,
AU  - G.
AU  - Carr,
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd008898.pub2
KW  - Jurisprudence
KW  - Juvenile Delinquency [rehabilitation] [statistics &amp; numerical data]
KW  - Program Evaluation [methods]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Young Adult[checkword]
KW  - Behav
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Restorative justice conferencing for reducing recidivism in young offenders (aged 7 to 21)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008898.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD008898.pub2/asset/CD008898.pdf?v=1&amp;t=iw7kz6fh&amp;s=80e79016adb02ba872f46a4cf2330de1a91b662c
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
Investigations of age effects on youth anxiety outcomes in randomized trials (RCTs) of cognitive behavior therapy (CBT) have failed to yield a clear result due to inadequate statistical power and methodologic weaknesses. We conducted an individual patient data metaanalysis to address this gap.QUESTION: Does age moderate CBT effect size, measured by a clinically and statistically significant interaction between age and CBT exposure?

**METHODS:** 
All English language RCTs of CBT for anxiety in 6-19 year olds were identified using systematic review methods. Investigators of eligible trials were invited to submit their individual patient data. The anxiety disorder interview schedule (ADIS) primary diagnosis severity score was the primary outcome. Age effects were investigated using multilevel modeling to account for study level data clustering and random effects.

**RESULTS:** 
Data from 17 of 23 eligible trials were obtained (74%); 16 studies and 1,171 (78%) cases were available for the analysis. No interaction between age and CBT exposure was found in a model containing age, sex, ADIS baseline severity score, and comorbid depression diagnosis (power &gt;= 80%). Sensitivity analyses, including modeling age as both a categorical and continuous variable, revealed this result was robust.

**CONCLUSIONS:** 
Adolescents who receive CBT in efficacy research studies show benefits comparable to younger children. However, CBT protocol modifications routinely carried out by expert trial therapists may explain these findings. Adolescent CBT protocols are needed to facilitate the transportability of efficacy research effects to usual care settings where therapists may have less opportunity for CBT training and expertise development.
AU  - Bennett,
AU  - K.
AU  - Manassis,
AU  - K.
AU  - Walter,
AU  - S.
AU  - D.
AU  - Cheung,
AU  - A.
AU  - Wilansky-Traynor,
AU  - P.
AU  - Diaz-Granados,
AU  - N.
AU  - Duda,
AU  - S.
AU  - Rice,
AU  - M.
AU  - Baer,
AU  - S.
AU  - Barrett,
AU  - P.
AU  - Bodden,
AU  - D.
AU  - Cobham,
AU  - V.
AU  - E.
AU  - Dadds,
AU  - M.
AU  - R.
AU  - Flannery-Schroeder,
AU  - E.
AU  - Ginsburg,
AU  - G.
AU  - Heyne,
AU  - D.
AU  - Hudson,
AU  - J.
AU  - L.
AU  - Kendall,
AU  - P.
AU  - C.
AU  - Liber,
AU  - J.
AU  - Warner,
AU  - C.
AU  - M.
AU  - Mendlowitz,
AU  - S.
AU  - Nauta,
AU  - M.
AU  - H.
AU  - Rapee,
AU  - R.
AU  - M.
AU  - Silverman,
AU  - W.
AU  - Siqueland,
AU  - L.
AU  - Spence,
AU  - S.
AU  - H.
AU  - Utens,
AU  - E.
AU  - Wood,
AU  - J.
AU  - J.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/da.22099
KW  - Adolescent
KW  - *Age Factors
KW  - *Anxiety Disorders/th [Therapy]
KW  - Child
KW  - *Cognitive Behavioral Therapy
KW  - Female
KW  - Humans
KW  - Male
KW  - Treatment Outcome
KW  - Young Adult
L1  - internal-pdf://3348644679/Bennett_et_al-2013-Depression_and_Anxiety.pdf
N1  - Depression &amp; Anxiety. 30(9):829-41, 2013 Sep.Journal ArticleMeta-AnalysisResearch Support, Non-U.S. Gov&#039;tSystematic Review
PY  - 2013
SP  - 829-41
TI  - Cognitive behavioral therapy age effects in child and adolescent anxiety: an individual patient data metaanalysis
VL  - 1
ER  -
TY  - JOUR
AB  - Attention-deficit hyperactivity disorder (ADHD) has a significant impact on children&#039;s classroom behaviour, daily functioning and experience of school life. However, the effects of drug treatment for ADHD on learning and academic achievement are not fully understood. This review was undertaken to describe the effects of methylphenidate, dexamfetamine, mixed amfetamine salts and atomoxetine on children&#039;s on-task behaviour and their academic performance, and to perform a meta-analysis to quantify these effects. 

Nine electronic databases were systematically searched for randomized controlled trials comparing drug treatment for ADHD against (i) no drug treatment, (ii) baseline (in crossover trials), or (iii) placebo; reporting outcomes encompassing measures of educational achievement within the classroom environment. 

Forty-three studies involving a pooled total of 2,110 participants were identified for inclusion. Drug treatment benefited children in the amount of school work that they completed, by up to 15 %, and less consistently improved children&#039;s accuracy in specific types of academic assignments, such as arithmetic. 

Similar improvements were seen in classroom behaviour, with up to 14 % more of children&#039;s time spent &quot;on task&quot;. Methylphenidate, dexamfetamine and mixed amfetamine formulations all showed beneficial effects on children&#039;s on-task behaviour and academic work completion. 

Atomoxetine was examined in two studies, and was found to have no significant effect. These review findings suggest that medication for ADHD has the potential to improve children&#039;s learning and academic achievement.
AD  - [Prasad, Vibhore; Brogan, Ellen; Mulvaney, Caroline; Grainge, Matthew; Stanton, Wendy; Sayal, Kapil] Univ Nottingham, Nottingham NG7 2RD, England. Prasad, V (reprint author), Univ Nottingham, Nottingham NG7 2RD, England. vibhore.prasad@nottingham.ac.uk
AN  - WOS:000317007400002
AU  - Prasad,
AU  - V.
AU  - Brogan,
AU  - E.
AU  - Mulvaney,
AU  - C.
AU  - Grainge,
AU  - M.
AU  - Stanton,
AU  - W.
AU  - Sayal,
AU  - K.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-012-0346-x
J2  - Eur. Child Adolesc. Psych.
KW  - ADHD Attention-deficit hyperactivity disorder Medication Education Achievement ATTENTION-DEFICIT/HYPERACTIVITY-DISORDER DEFICIT HYPERACTIVITY DISORDER EXTENDED-RELEASE METHYLPHENIDATE QUALITY-OF-LIFE STIMULANT MEDICATION ANALOG CLASSROOM SOCIAL-BEHAVIOR
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 118EY Times Cited: 8 Cited Reference Count: 80 Prasad, Vibhore Brogan, Ellen Mulvaney, Caroline Grainge, Matthew Stanton, Wendy Sayal, Kapil NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC) for Nottinghamshire, Derbyshire, Lincolnshire; NIHR KS is partly funded by the NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC) for Nottinghamshire, Derbyshire, Lincolnshire. VP is funded by the NIHR as a Doctoral Research Fellow and was previously funded by the NIHR as an In-Practice Fellow. 8 SPRINGER NEW YORK EUR CHILD ADOLES PSY
PY  - 2013
SP  - 203-216
T2  - European Child &amp; Adolescent Psychiatry
TI  - How effective are drug treatments for children with ADHD at improving on-task behaviour and academic achievement in the school classroom? A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000317007400002http://download.springer.com/static/pdf/344/art%253A10.1007%252Fs00787-012-0346-x.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-012-0346-x&amp;token2=exp=1434977920~acl=%2Fstatic%2Fpdf%2F344%2Fart%25253A10.1007%25252Fs00787-012-0346-x.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-012-0346-x*~hmac=86ba5c809f79889f32a7b93bbee9fec849b619aa1356c53857166ac59693b0be
VL  - 22
ER  -
TY  - JOUR
AB  - The primary purpose of this quantitative synthesis of single-subject research was to investigate the relative effectiveness of function-based and non-function-based behavioral interventions for students diagnosed with attention-deficit/hyperactivity disorder. 

In addition, associations between various participant, assessment, and intervention characteristics were investigated. Eighty-two studies incorporating a total of 168 participants were included. 

Because no single effect size metric has garnered absolute support to date, three different effect size metrics were calculated: the standard mean difference, percent exceeding the median baseline phase, and improvement rate difference. 

Overall, function-based interventions were associated with significantly larger effects than non-function-based interventions. Interventions based on the functional analysis manipulations were also associated with larger effects. 

Limitations, directions for future research, and implications for practice are discussed. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - Miller, Faith G.: faith.miller@uconn.edu Miller, Faith G.: Department of Educational Psychology, University of Connecticut, U-3064, Storrs, CT, US, 06269-3064, faith.miller@uconn.edu Miller, Faith G.: Pennsylvania State University, University Park, PA, US Lee, David L.: Pennsylvania State University, University Park, PA, US
AN  - 2013-22715-001
AU  - Miller,
AU  - F.
AU  - G.
AU  - Lee,
AU  - D.
AU  - L.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10864-013-9174-4
DP  - Ovid Technologies
KW  - intervention effectiveness, attention deficit hyperactivity disorder, functional behavioral assessments, special education students *Behavioral Assessment *School Based Intervention *Special Education Students *Treatment Effectiveness Evaluation Attenti
LA  - English
M3  - Meta Analysis
PY  - 2013
SP  - 253-282
T2  - Journal of Behavioral Education
TI  - Do functional behavioral assessments improve intervention effectiveness for students diagnosed with ADHD? A single-subject meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-22715-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10864-013-9174-4&amp;issn=1053-0819&amp;isbn=&amp;volume=22&amp;issue=3&amp;spage=253&amp;pages=253-282&amp;date=2013&amp;title=Journal+of+Behavioral+Education&amp;atitle=Do+functional+behavioral+assessments+improve+intervention+effectiveness+for+students+diagnosed+with+ADHD%3F+A+single-subject+meta-analysis.&amp;aulast=Miller&amp;pid=%3Cauthor%3EMiller%2C+Faith+G%3C%2Fauthor%3E%3CAN%3E2013-22715-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10864-013-9174-4http://download.springer.com/static/pdf/551/art%253A10.1007%252Fs10864-013-9174-4.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10864-013-9174-4&amp;token2=exp=1435232102~acl=%2Fstatic%2Fpdf%2F551%2Fart%25253A10.1007%25252Fs10864-013-9174-4.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10864-013-9174-4*~hmac=062aef743f1ca80d4d4f24dad198c0cc617ba9f14a9a3092ecfeacf7f8da2f2f
VL  - 22
ER  -
TY  - JOUR
AB  - **Background:** 
The prevalence of opiate use among pregnant women can range from 1% to 2% to as high as 21%. Heroin crosses the placenta and pregnant, opiate-dependent women experience a six-fold increase in maternal obstetric complications such as low birth weight, toxaemia, third trimester bleeding, malpresentation, puerperal morbidity, fetal distress and meconium aspiration. Neonatal complications include narcotic withdrawal, postnatal growth deficiency, microcephaly, neuro-behavioural problems, increased neonatal mortality and a 74-fold increase in sudden infant death syndrome.

**Objectives:** 
To assess the effectiveness of any maintenance treatment alone or in combination with psychosocial intervention compared to no intervention, other pharmacological intervention or psychosocial interventions for child health status, neonatal mortality, retaining pregnant women in treatment and reducing the use of substances.

**Search methods:** 
We searched the Cochrane Drugs and Alcohol Group Trials Register (September 2013), PubMed (1966 to September 2013), CINAHL (1982 to September 2013), reference lists of relevant papers, sources of ongoing trials, conference proceedings and national focal points for drug research. We contacted authors of included studies and experts in the field.

**Selection criteria:** 
Randomised controlled trials assessing the efficacy of any maintenance pharmacological treatment for opiate-dependent pregnant women.

**Data collection and analysis:** 
We used the standard methodological procedures expected by The Cochrane Collaboration.

**Main results:** 
We found four trials with 271 pregnant women. Three compared methadone with buprenorphine and one methadone with oral slow-release morphine. Three out of four studies had adequate allocation concealment and were double-blind. The major flaw in the included studies was attrition bias: three out of four had a high drop-out rate (30% to 40%) and this was unbalanced between groups.Methadone versus buprenorphine: the drop-out rate from treatment was lower in the methadone group (risk ratio (RR) 0.64, 95% confidence interval (CI) 0.41 to 1.01, three studies, 223 participants). There was no statistically significant difference in the use of primary substance between methadone and buprenorphine (RR 1.81, 95% CI 0.70 to 4.69, two studies, 151 participants). For both, we judged the quality of evidence as low. Birth weight was higher in the buprenorphine group in the two trials that could be pooled (mean difference (MD) -365.45 g (95% CI -673.84 to -57.07), two studies, 150 participants). The third study reported that there was no statistically significant difference. For APGAR score neither of the studies which compared methadone with buprenorphine found a significant difference. For both, we judged the quality of evidence as low. Many measures were used in the studies to assess neonatal abstinence syndrome. The number of newborns treated for neonatal abstinence syndrome, which is the most critical outcome, did not differ significantly between groups. We judged the quality of evidence as very low.Methadone versus slow-release morphine: there was no drop-out in either treatment group. Oral slow-release morphine seemed superior to methadone for abstinence from heroin use during pregnancy (RR 2.40, 95% CI 1.00 to 5.77, one study, 48 participants). We judged the quality of evidence as moderate.Only one study which compared methadone with buprenorphine reported side effects. For the mother there was no statistically significant difference; for the newborns in the buprenorphine group there were significantly fewer serious side effects.In the comparison between methadone and slow-release morphine no side effects were reported for the mother, whereas one child in the methadone group had central apnoea and one child in the morphine group had obstructive apnoea.

**Authors&#039; conclusions:** 
We did not find sufficient significant differences between methadone and buprenorphine or slow-release morphineto allow us to conclude that one treatment is superior to another for all relevant outcomes. While methadone s e s superior in terms of retaining patients in treatment, buprenorphine seems to lead to less severe neonatal abstinence syndrome. Additionally, even though a multi-centre, international trial with 175 pregnant women has recently been completed and its results published and included in this review, the body of evidence is still too small to draw firm conclusions about the equivalence of the treatments compared. There is still a need for randomised controlled trials of adequate sample size comparing different maintenance treatments.
AN  - CD006318
AU  - Minozzi,
AU  - S.
AU  - Amato,
AU  - L.
AU  - Bellisario,
AU  - C.
AU  - Ferri,
AU  - M.
AU  - Davoli,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd006318.pub2
KW  - Birth Weight [drug effects]
KW  - Buprenorphine [adverse effects] [therapeutic use]
KW  - Delayed-Action Preparations [adverse effects] [therapeutic use]
KW  - Methadone [adverse effects] [therapeutic use]
KW  - Morphine [adverse effects] [therapeutic use]
KW  - Narcotics [adverse effects] [agonists] [therapeutic use]
KW  - Opioid-Related Disorders [rehabilitation]
KW  - Pregnancy Complications [rehabilitation]
KW  - Randomized Controlled Trials as Topic
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Infant, Newborn[checkword]
KW  - Pregnancy[checkword]
KW  - Addictn
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Maintenance agonist treatments for opiate-dependent pregnant women
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006318.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006318.pub3/asset/CD006318.pdf?v=1&amp;t=iw7k08jd&amp;s=4544c3bd8ef69e4286af175fb1e88b9ec82d90c5
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Psychodynamically based brief psychotherapy is frequently used in clinical practice for a range of common mental disorders in children and adolescents. To our knowledge, there have been no meta-analyses to evaluate the effectiveness of these therapies. 

**METHOD:  **
After a broad search, we meta-analyzed controlled outcome studies of short-term psychodynamic psychotherapies (STPP, 40 or fewer sessions). We also performed sensitivity analyses and evaluated the risk of bias in this body of studies. 

**RESULTS:  **
We found 11 studies with a total of 655 patients covering a broad range of conditions including depression, anxiety disorders, anorexia nervosa, and borderline personality disorder. STPP did not separate from what were mostly robust treatment comparators, but there were some subgroup differences. Robust (g = 1.07, 95% CI = 0.80-1.34) within group effect sizes were observed suggesting the treatment may be effective. These effects increased in follow up compared to post treatment (overall, g = 0.24, 95% CI = 0.00-0.48), suggesting a tendency toward increased gains. Heterogeneity was high across most analyses, suggesting that these data need be interpreted with caution. 

**CONCLUSION:  **
This review suggests that STPP may be effective in children and adolescents across a range of common mental disorders.

Copyright &copy; 2013 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
AD  - Abbass,Allan A. Department of PsychiatryDalhousie University, Halifac, NS, Canada. allan.abbass@dal.ca
AN  - 23880496
AU  - Abbass,
AU  - A.
AU  - A.
AU  - Rabung,
AU  - S.
AU  - Leichsenring,
AU  - F.
AU  - Refseth,
AU  - J.
AU  - S.
AU  - Midgley,
AU  - N.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2013.05.014
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
KW  - Adolescent Child Humans *Mental Disorders/th [Therapy] Models, Psychological *Psychotherapy, Brief/st [Standards] *Psychotherapy, Psychodynamic/st [Standards] *Treatment Outcome
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Abbass, Allan A Rabung, Sven Leichsenring, Falk Refseth, Johanne S Midgley, Nick Comment in: J Am Acad Child Adolesc Psychiatry. 2013 Nov;52(11):1213-4; PMID: 24157395 Comment in: J Am Acad Child Adolesc Psychiatry. 2013 Nov;52(11):1214-5; PMID: 24157396 S0890-8567(13)00341-9
PY  - 2013
SP  - 863-75
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Psychodynamic psychotherapy for children and adolescents: a meta-analysis of short-term psychodynamic models
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23880496
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23880496&amp;id=doi:10.1016%2Fj.jaac.2013.05.014&amp;issn=0890-8567&amp;isbn=&amp;volume=52&amp;issue=8&amp;spage=863&amp;pages=863-75&amp;date=2013&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Psychodynamic+psychotherapy+for+children+and+adolescents%3A+a+meta-analysis+of+short-term+psychodynamic+models.&amp;aulast=Abbass&amp;pid=%3Cauthor%3EAbbass+AA%3C%2Fauthor%3E%3CAN%3E23880496%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0890856713003419/1-s2.0-S0890856713003419-main.pdf?_tid=e06bebde-1673-11e5-8ec1-00000aab0f02&amp;acdnat=1434712444_88c82581e0e35984b1dca0a90a03ac8c
VL  - 52
ER  -
TY  - JOUR
AB  - **Background:** 
Postnatal psychosis is a worldwide life-threatening condition that affects one to two in every 1000 new mothers. It has an abrupt onset within a month of childbirth. Affected new mothers rapidly develop frank psychosis, cognitive impairment, and disorganised behaviours. Factors that increase the risk of postnatal psychosis include primiparous mothers who are single, women who are older, or with a past psychiatric history and family history of affective psychosis, prenatal depression and autoimmune thyroid dysfunction. The risk of a future postnatal recurrence is 25% to 57%. Preventive interventions for postnatal psychosis aim at identifying women with risk factors, early recognition of imminent psychosis through screening, and preventive drug therapy. Mood stabilisers, antipsychotic drugs and hormone therapy may be beneficial in the prevention of postnatal psychotic episodes in women at risk.

**Objectives:** 
To investigate the best available evidence for interventions aimed at preventing postnatal psychosis.

**Search methods:** 
We searched the Cochrane Schizophrenia Group Trials Register and the Cochrane Central Register of Controlled Trials (CENTRAL) in October 2012 using the search strategy of the Cochrane Schizophrenia Group.Selection criteria: All randomised controlled trials relevant to the prevention of postnatal psychosis.

**Data collection and analysis:** 
Two review authors inspected all citations to ensure reliable selection. If we had included relevant trials, we planned to assess the methodological quality of identified trials using the criteria recommended in the Cochrane Handbook for Systematic Reviews of Interventions. Two review authors would have independently extracted data. For homogenous dichotomous data, we planned to calculate the risk ratio (RR), 95% confidence interval (CI), and the number needed to treat to benefit/harm (NNTB/NNTH) on an intention-to-treat basis.

**Main results:** 
There are no included studies in this review. The electronic search produced three relevant references, among which we identified two old planned trials that seem never to have started, and one which we excluded a study because it was a report of a case series.

**Authors&#039; conclusions:** 
This is not an empty review - it is a review full of unanswered questions. Despite growing interest in women?s mental health, the literature in the area of postnatal psychosis is still very limited. It seems that clinicians have no choice but to continue with their current practices guided solely by varied clinical judgement. Women at risk of postnatal psychosis and their relatives are justified to be disappointed in the medical/research fraternity. A post hoc PubMed topic (not methodology-specific) search identified mainly case series. Policy makers have no trial-based evidence upon which to base their guidelines. Certainly, preventive interventions for postnatal psychosis are difficult to justify with confidence without well-designed, well-conducted, and well-reported randomised studies. Available publications suggest that such studies are possible and funders of research may wish to make this work a priority.
AN  - CD009991
AU  - Essali,
AU  - A.
AU  - Alabed,
AU  - S.
AU  - Guul,
AU  - A.
AU  - Essali,
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1093/schbul/sbt073
KW  - Psychotic Disorders [prevention &amp; control]
KW  - Puerperal Disorders [prevention &amp; control]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Schiz
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Preventive interventions for postnatal psychosis
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009991.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009991.pub2/asset/CD009991.pdf?v=1&amp;t=iw7kr19t&amp;s=b0ab3c564af62d77a7fcd54b15b40e41ea800c81
ER  -
TY  - JOUR
AB  - **Background:** 
There is a need to identify effective and safe treatments for depression in children and adolescents. While tricyclic drugs are effective in treating depression in adults, individual studies involving children and adolescents have been equivocal. Prescribing of tricyclic drugs for depression in children and adolescents is now uncommon, but an accurate estimate of their efficacy is helpful as a comparator for other drug treatments for depression in this age group. This is an update of a Cochrane review first published in 2000 and updated in 2002, 2006 and 2010.

**Objectives:** 
To assess the effects of tricyclic drugs compared with placebo for depression in children and adolescents and to determine whether there are differential responses to tricyclic drugs between child and adolescent patient populations.Search methods: We conducted a search of the Cochrane Depression, Anxiety and Neurosis Review Group&#039;s Specialised Register (CCDANCTR) (to 12 April 2013), which includes relevant randomised controlled trials from the following bibliographic databases: the Cochrane Central Register of Controlled Trials (CENTRAL) (all years), EMBASE (1974-), MEDLINE (1950-) and PsycINFO (1967-). The bibliographies of previously published reviews and papers describing original research were cross-checked. We contacted authors of relevant abstracts in conference proceedings of the American Academy of Child and Adolescent Psychiatry, and we handsearched the Journal of the American Academy of Child and Adolescent Psychiatry (1978 to 1999).

**Selection criteria:**
Randomised controlled trials comparing the efficacy of orally administered tricyclic drugs with placebo in depressed people aged 6 to 18 years.

**Data collection and analysis:** 
One of two review authors selected the trials, assessed their quality, and extracted trial and outcome data. A second review author assessed quality and checked accuracy of extracted data. Most studies reported multiple outcome measures including depression scales and clinical global impression scales. For each study, we took the best available depression measure as the index measure of depression outcome. We established predetermined criteria to assist in the ranking of measures. Where study authors reported categorical outcomes, we calculated individual and pooled risk ratios for non-improvement in treated compared with control subjects. For continuous outcomes, we calculated pooled effect sizes as the number of standard deviations by which the change in depression scores for the treatment group exceeded those for the control group.

**Main results:** 
Fourteen trials (590 participants) were included. No overall difference was found for the primary outcome of response to treatment compared with placebo (risk ratio (RR) 1.07, 95% confidence interval (CI) 0.91 to 1.26; 9 trials, N = 454). There was a small reduction in depression symptoms (standardised mean difference (SMD) -0.32, 95% CI -0.59 to -0.04; 13 trials, N = 533), but the evidence was of low quality. Subgroup analyses suggested a small reduction in depression symptoms among adolescents (SMD -0.45, 95% CI -0.83 to -0.007), and negligible change among children (SMD 0.15, 95% CI -0.34 to 0.64). Treatment with a tricyclic antidepressant caused more vertigo (RR 2.76, 95% CI 1.73 to 4.43; 5 trials, N = 324), orthostatic hypotension (RR 4.86, 95% CI 1.69 to 13.97; 5 trials, N = 324), tremor (RR 5.43, 95% CI 1.64 to 17.98; 4 trials, N = 308) and dry mouth (RR 3.35, 95% CI 1.98 to 5.64; 5 trials, N = 324) than did placebo, but no differences were found for other possible adverse effects. Wide CIs and the probability of selective reporting mean that there was very low-quality evidence for adverse events.There was heterogeneity across the studies in the age of participants, treatment setting, tricyclic drug administered and outcome measures. Statistical heterogeneity was identified for reduction in depressive symptoms, but not for rates of remission or response. As such, the findings from analyses of pooled data should be interpreted with caution.We judged none of th s trials to be at low risk of bias, with limited information about many aspects of risk of bias, high dropout rates, and issues regarding measurement instruments and the clinical usefulness of outcomes, which were often variously defined across trials.

**Authors&#039; conclusions:** 
Data suggest tricyclic drugs are not useful in treating depression in children. There is marginal evidence to support the use of tricyclic drugs in the treatment of depression in adolescents.
AN  - CD002317
AU  - Hazell,
AU  - P.
AU  - Mirzaie,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd002317.pub2
KW  - Administration, Oral
KW  - Age Factors
KW  - Antidepressive Agents, Tricyclic [adverse effects] [therapeutic use]
KW  - Confidence Intervals
KW  - Depression [drug therapy]
KW  - Odds Ratio
KW  - Outcome Assessment (Health Care)
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Tricyclic drugs for depression in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002317.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD002317.pub2/asset/CD002317.pdf?v=1&amp;t=iw7lcnrd&amp;s=1d12a43f13e7aa827e1c975995f4fefbd8d02f33
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
To assess the efficacy and safety of topiramate for children with Tourette syndrome. 

**METHODS: **
Randomized controlled trials evaluating topiramate for children with Tourette syndrome were identified from the Cochrane library, PubMed, Cochrane Central, Embase, CBM, CNKI, VIP, WANG FANG database, and relevant reference lists. Two reviewers independently selected trials, assessed trial quality, and extracted the data. Disagreement was resolved by discussion. Quality assessment referred to the Cochrane Handbook for Systematic Reviews of Interventions (version 5.0.1.). 

**RESULTS: **
Fourteen trials involving 1003 patients were included, of which 720 cases were male (71.8%). Ages were 2 to 17 years old. The general quality of included randomized controlled trials was poor. All trials were positive drug-controlled (12 randomized controlled trials used haloperidol as control, 2 used tiapride). The follow-up period was from 20 days to 12 months. Meta-analysis of 3 trials (n = 207), in which tics symptoms control was assessed by Yale Global Tic Severity Scale, suggested that there was significant difference in the mean change of Yale Global Tic Severity Scale score during the treatment period (mean difference = -7.74, 95% CI [-10.49, -4.99], I(2) = 0) between topiramate and control groups. Meta-analysis of 9 trials (n = 668) evaluating tics symptoms control &gt; 50% suggested that there was no significant difference in reduction of tics between topiramate and control group during the treatment period (relative ratio = 1.36, 95% CI [0.90, 2.06], I(2) = 0). Adverse events were reported in 13 trials. Drowsiness (3.3-16%), loss of appetite (4-16.7%), cognitive dysfunction (7.89-12.5%), and weight loss (6-10.5%) were common adverse events. 

**CONCLUSIONS: **
The current evidence is promising but not yet sufficient to support the routine use of topiramate for Tourette syndrome in children due to low quality of the study designs. It deserves to confirm in further high-quality, placebo-controlled trials.

Copyright &copy; 2013 Elsevier Inc. All rights reserved.
AD  - Yang,Chun-Song. Department of Pharmacy, West China Second Hospital, Sichuan University, Chengdu, China.
AN  - 24139534
AU  - Yang,
AU  - C.
AU  - S.
AU  - Zhang,
AU  - L.
AU  - L.
AU  - Zeng,
AU  - L.
AU  - N.
AU  - Huang,
AU  - L.
AU  - Liu,
AU  - Y.
AU  - T.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.pediatrneurol.2013.05.002
DP  - Ovid Technologies
J2  - Pediatr Neurol
KW  - Adolescent *Anticonvulsants/tu [Therapeutic Use] Child Child, Preschool Databases, Factual/sn [Statistics &amp; Numerical Data] Female *Fructose/aa [Analogs &amp; Derivatives] Fructose/tu [Therapeutic Use] Humans Male Randomized Controlled Trials as Topic *Tour
LA  - English
M3  - Meta-Analysis
N1  - Yang, Chun-Song Zhang, Ling-Li Zeng, Li-Nan Huang, Liang Liu, Yan-Tao S0887-8994(13)00292-0
PY  - 2013
SP  - 344-50
T2  - Pediatric Neurology
TI  - Topiramate for Tourette&#039;s syndrome in children: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24139534 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24139534&amp;id=doi:10.1016%2Fj.pediatrneurol.2013.05.002&amp;issn=0887-8994&amp;isbn=&amp;volume=49&amp;issue=5&amp;spage=344&amp;pages=344-50&amp;date=2013&amp;title=Pediatric+Neurology&amp;atitle=Topiramate+for+Tourette%27s+syndrome+in+children%3A+a+meta-analysis.&amp;aulast=Yang&amp;pid=%3Cauthor%3EYang+CS%3C%2Fauthor%3E%3CAN%3E24139534%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0887899413002920/1-s2.0-S0887899413002920-main.pdf?_tid=f16ac242-18a9-11e5-a957-00000aab0f27&amp;acdnat=1434955568_21b8885d337acff7c6ae7ea07e07e864
VL  - 49
ER  -
TY  - JOUR
AB  - **Objective: **
Attention-deficit/hyperactivity disorder (ADHD) is a psychiatric disorder affecting 5% of children. Methylphenidate (MPH) is a common medication for ADHD. Studies examining MPH&#039;s effect on pediatric ADHD patients&#039; brain function using functional magnetic resonance imaging (fMRI) have not been compiled. The goals of this systematic review were to determine (1) which areas of the brain in pediatric ADHD patients are modulated by a single dose of MPH, (2) whether areas modulated by MPH differ by task type performed during fMRI data acquisition, and (3) whether changes in brain activation due to MPH relate to clinical improvements in ADHD-related symptoms. 

**Methods: **
We searched the electronic databases PubMed and PsycINFO (1967-2011) using the following terms: ADHD AND (methylphenidate OR MPH OR ritalin) AND (neuroimaging OR MRI OR fMRI OR BOLD OR event related), and identified 200 abstracts, 9 of which were reviewed based on predefined criteria. 

**Results: **
In ADHD patients the middle and inferior frontal gyri, basal ganglia, and cerebellum were most often affected by MPH. The middle and inferior frontal gyri were frequently affected by MPH during inhibitory control tasks. Correlation between brain regions and clinical improvement was not possible due to the lack of symptom improvement measures within the included studies. 

**Conclusions: **
Throughout nine task-based fMRI studies investigating MPH&#039;s effect on the brains of pediatric patients with ADHD, MPH resulted in increased activation within frontal lobes, basal ganglia, and cerebellum. In most cases, this increase &quot;normalized&quot; activation of at least some brain areas to that seen in typically developing children.
AD  - [Czerniak, Suzanne M.; Sikoglu, Elif M.; King, Jean A.; Kennedy, David N.; Mick, Eric; Frazier, Jean; Moore, Constance M.] Univ Massachusetts, Sch Med, Amherst, MA 01003 USA. Moore, CM (reprint author), Psychiat CCNI, 303 Belmont St, Worcester, MA 01604 USA. Constance.Moore@umassmed.edu
AN  - WOS:000321098500003
AU  - Czerniak,
AU  - S.
AU  - M.
AU  - Sikoglu,
AU  - E.
AU  - M.
AU  - King,
AU  - J.
AU  - A.
AU  - Kennedy,
AU  - D.
AU  - N.
AU  - Mick,
AU  - E.
AU  - Frazier,
AU  - J.
AU  - Moore,
AU  - C.
AU  - M.
DA  - May-Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/HRP.0b013e318293749e
J2  - Harv. Rev. Psychiatr.
KW  - ADHD fMRI methylphenidate neuroimaging pediatric DEFICIT HYPERACTIVITY DISORDER ATTENTION-DEFICIT/HYPERACTIVITY DISORDER FUNCTIONAL MAGNETIC-RESONANCE MEDICATION-NAIVE BOYS EVENT-RELATED FMRI RESPONSE-INHIBITION METAANALYSIS ADOLESCENTS ACTIVATION CHILD
L1  - internal-pdf://2412703184/Czerniak-2013-Areas of the Brain Modulated by.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 173SF Times Cited: 0 Cited Reference Count: 46 Czerniak, Suzanne M. Sikoglu, Elif M. King, Jean A. Kennedy, David N. Mick, Eric Frazier, Jean Moore, Constance M. University of Massachusetts Medical School Supported, in part, by a start-up grant (to Dr. Moore) from the University of Massachusetts Medical School. LIPPINCOTT WILLIAMS &amp; WILKINS PHILADELPHIA HARVARD REV PSYCHIAT
PY  - 2013
SP  - 151-162
T2  - Harvard Review of Psychiatry
TI  - Areas of the Brain Modulated by Single-Dose Methylphenidate Treatment in Youth with ADHD During Task-Based fMRI: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000321098500003http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103657/pdf/nihms589347.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103657/pdf/nihms589347.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - The present meta-analytic review examined effectiveness of the Incredible Years parent training (IYPT) regarding disruptive and prosocial child behavior, and aimed to explain variability in intervention outcomes. 

Fifty studies, in which an intervention group receiving the IYPT was compared to a comparison group immediately after intervention, were included in the analyses. Results showed that the IYPT is an effective intervention. 

Positive effects for distinct outcomes and distinct informants were found, including a mean effect size of d = .27 concerning disruptive child behavior across informants. For parental report, treatment studies were associated with larger effects (d = .50) than indicated (d = .20) and selective (d = .13) prevention studies. 

Furthermore, initial severity of child behavior revealed to be the strongest predictor of intervention effects, with larger effects for studies including more severe cases. 

Findings indicate that the IYPT is successful in improving child behavior in a diverse range of families, and that the parent program may be considered well-established. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - A Menting, Ankie T. A.: A.T.A.Menting@uu.nl Menting, Ankie T. A.: Utrecht University, PO Box 80140, Utrecht, Netherlands, 3508 TC, A.T.A.Menting@uu.nl Menting, Ankie T. A.: Utrecht University, Utrecht, Netherlands de Castro, Bram Orobio: Utrecht University, Utrecht, Netherlands Matthys, Walter: Department of Child and Adolescent Studies, Utrecht University, Utrecht, Netherlands
AN  - 2013-42151-002
AU  - Menting,
AU  - A.
AU  - T.
AU  - Orobio
AU  - de
AU  - Castro,
AU  - B.
AU  - Matthys,
AU  - W.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2013.07.006
DP  - Ovid Technologies
KW  - Incredible Years parent training, child behavior, disruptive &amp; prosocial behavior, intervention outcomes *Behavior Problems *Intervention *Parent Training *Prosocial Behavior *Treatment Outcomes Childrearing &amp; Child Care [2956] Human Childhood (birth-12
LA  - English
M3  - Meta Analysis
PY  - 2013
SP  - 901-913
T2  - Clinical Psychology Review
TI  - Effectiveness of the Incredible Years parent training to modify disruptive and prosocial child behavior: A meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-42151-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.cpr.2013.07.006&amp;issn=0272-7358&amp;isbn=&amp;volume=33&amp;issue=8&amp;spage=901&amp;pages=901-913&amp;date=2013&amp;title=Clinical+Psychology+Review&amp;atitle=Effectiveness+of+the+Incredible+Years+parent+training+to+modify+disruptive+and+prosocial+child+behavior%3A+A+meta-analytic+review.&amp;aulast=Menting&amp;pid=%3Cauthor%3EMenting%2C+Ankie+T.+A%3C%2Fauthor%3E%3CAN%3E2013-42151-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735813000949/1-s2.0-S0272735813000949-main.pdf?_tid=154a32a6-1972-11e5-a9ce-00000aacb361&amp;acdnat=1435041528_0955d0a5d6b9f39aad3b0e15a2cf5d2a
VL  - 33
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Attention-deficit/hyperactivity disorder (ADHD) is associated with a broad range of neuropsychological impairments. The relationship between these neuropsychological deficits and the defining symptoms of ADHD seems more complex than originally thought. Methylphenidate (MPH) is an effective treatment for ADHD symptoms, but its impact on cognition is less clearly understood. 

**METHODS: **
With a common systematic search strategy and a rigorous coding and data extraction strategy across domains, we searched electronic databases to identify published placebo controlled trials that compared MPH and placebo on executive and nonexecutive memory, reaction time, reaction time variability and response inhibition in children and adolescents (5-18 years) with a formal diagnosis of ADHD. 

**RESULTS: **
Sixty studies were included in the review, of which 36 contained sufficient data for meta-analysis. Methylphenidate was superior to placebo in all five meta-analyses: executive memory, standardized mean difference (SMD) .26, 95% confidence interval (CI): -.39 to -.13; non-executive memory, SMD .60, 95% CI: -.79 to -.41; reaction time, SMD .24, 95% CI: -.33 to -.15; reaction time variability, SMD .62, 95% CI: -.90 to -.34; response inhibition, SMD .41, 95% CI: -.55 to -.27. 

**CONCLUSIONS: **
These data support the potentially important effects of MPH on various aspects of cognition known to be associated with ADHD. Consideration should be given to adding cognitive outcomes to the assessment of treatment outcome in ADHD, considering the complexity of the relationship between ADHD symptoms and cognition. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AN  - 2013-39939-001
AU  - Coghill,
AU  - D.
AU  - R.
AU  - Seth,
AU  - S.
AU  - Pedroso,
AU  - S.
AU  - Usala,
AU  - T.
AU  - Currie,
AU  - J.
AU  - Gagliano,
AU  - A.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.biopsych.2013.10.005
DP  - Ovid Technologies
KW  - Health &amp; Mental Health Treatment &amp; Prevention [3300]
PY  - 2013
SP  - No Pagination Specified
T2  - Biological Psychiatry
TI  - Effects of methylphenidate on cognitive functions in children and adolescents with attention-deficit/hyperactivity disorder: Evidence from a systematic review and a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-39939-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.biopsych.2013.10.005&amp;issn=0006-3223&amp;isbn=&amp;volume=76&amp;issue=8&amp;spage=No&amp;pages=No+Pagination+Specified&amp;date=2013&amp;title=Biological+Psychiatry&amp;atitle=Effects+of+methylphenidate+on+cognitive+functions+in+children+and+adolescents+with+attention-deficit%2Fhyperactivity+disorder%3A+Evidence+from+a+systematic+review+and+a+meta-analysis.&amp;aulast=Coghill&amp;pid=%3Cauthor%3ECoghill%2C+David+R%3C%2Fauthor%3E%3CAN%3E2013-39939-001%3C%2FAN%3E%3CDT%3E%3C%2FDT%3Ehttp://ac.els-cdn.com/S0006322313009116/1-s2.0-S0006322313009116-main.pdf?_tid=297488a6-18b6-11e5-a957-00000aab0f27&amp;acdnat=1434960816_4481f1c579eb89b5b79a1017e41f23aa
ER  -
TY  - JOUR
AB  - Purpose: 
To evaluate the effectiveness of behavioral interventions designed to treat stuttering in children. 

Method: 
Studies were included for review if (a) the treatment was a behavioral intervention, (b) participants were between 2 and 18 years old, (c) the design was an experimental or quasi-experimental group design, and (d) the reported outcome measure assessed stuttering. An electronic search of 8 databases yielded a total of 9 studies, representing 327 treated participants across 7 different intervention types. Data were extracted for participant, treatment, and outcome characteristics as well as for methodological quality. 

Results: 
An analysis of the treatment effects yielded significant positive effects approaching 1 SD when compared with a nontreatment control group. No significant differences emerged for studies comparing 2 different treatments. 

Conclusion: 
Conclusions drawn from the extant research suggest that data to support the efficacy of behavioral intervention in children exists for a limited number of intervention strategies, based on a meager number of methodologically acceptable studies.
AD  - [Nye, Chad; Vanryckeghem, Martine; Schwartz, Jamie B.] Univ Cent Florida, Orlando, FL 32816 USA. [Herder, Carl] Amer Inst Stuttering, New York, NY USA. [Turner, Herbert M., III] Analytica, Phoenixville, PA USA. [Howard, Courtney] Adv Therapy, Springfield, MO USA. Nye, C (reprint author), Univ Cent Florida, Orlando, FL 32816 USA. chad.nye@ucf.edu
AN  - WOS:000322446400012
AU  - Nye,
AU  - C,
AU  - Vanryckeghem,
AU  - M.
AU  - Schwartz,
AU  - J.
AU  - B.
AU  - Herder,
AU  - C.
AU  - Turner,
AU  - H.
AU  - M.
AU  - Howard,
AU  - C.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1044/1092-4388(2012/12-0036)
J2  - J. Speech Lang. Hear. Res.
KW  - stuttering systematic review children efficacy RANDOMIZED CONTROLLED-TRIAL LIDCOMBE-PROGRAM METHODOLOGICAL QUALITY FOLLOW-UP EFFICACY THERAPY IMPACT Audiology &amp; Speech-Language Pathology Linguistics Rehabilitation
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 191WU Times Cited: 2 Cited Reference Count: 43 Nye, Chad Vanryckeghem, Martine Schwartz, Jamie B. Herder, Carl Turner, Herbert M., III Howard, Courtney 2 AMER SPEECH-LANGUAGE-HEARING ASSOC ROCKVILLE J SPEECH LANG HEAR R
PY  - 2013
SP  - 921-932
T2  - Journal of Speech Language and Hearing Research
TI  - Behavioral Stuttering Interventions for Children and Adolescents: A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000322446400012http://jslhr.pubs.asha.org/article.aspx?articleid=1797035http://jslhr.pubs.asha.org/data/Journals/JSLHR/929529/jslhr_56_3_921.pdf
VL  - 56
ER  -
TY  - JOUR
AB  - Dropping out of secondary school is associated with numerous detrimental consequences, including low wages, unemployment, incarceration, and poverty. 

Fortunately, many school- and community- based prevention and intervention programs are available for the general population and at-risk students. The objective of this systematic review was to summarize the available evidence on the effects of prevention and intervention programs for increasing school completion or reducing school dropout among primary and secondary students. 

Overall, dropout programs (152 studies; 317 independent samples) were effective in reducing school dropout (or increasing school completion). The random effects weighted mean odds ratio for the general programs was 1.72. Using the average dropout rate for control groups of 21.1%, the mean odds ratio of 1.72 translates into a dropout rate of 13% for intervention groups. Moderator analyses indicated that study methods were associated with effect size magnitude. 

Effect sizes were therefore adjusted for methodological characteristics to examine the effects of different program types net of the influence of method. Effects were generally consistent across different types of programs and for different types of participant samples. Overall, results indicated that most school- and community-based programs were effective in decreasing school dropout. However, higher implementation quality tended to be associated with larger effects. 

Given the minimal variation in effects across program types, the review shows that-regardless of type-dropout prevention and intervention programs are likely to be effective if they are well implemented and appropriate for the local environment. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Wilson, Sandra Jo: sandra.j.wilson@vanderbilt.edu; Tanner-Smith, Emily E.: e.tanner-smith@vanderbilt.edu Wilson, Sandra Jo: Peabody Research Institute, 230 Appleton Place, PMB 181, Nashville, TN, US, 37203-5721, sandra.j.wilson@vanderbilt.edu Wilson, Sandra Jo: Department of Special Education, Vanderbilt University, Nashville, TN, US Tanner-Smith, Emily E.: Peabody Research Institute, Vanderbilt University, Nashville, TN, US
AN  - 2014-03819-001
AU  - Wilson,
AU  - S.
AU  - J.
AU  - Tanner-Smith,
AU  - E.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.campbellcollaboration.org/library/dropout-prevention-intervention-programmes.html
DP  - Ovid Technologies
KW  - dropout prevention, school intervention programs, school-aged children, secondary school students *Elementary School Students *High School Students *Program Evaluation *School Based Intervention *School Dropouts Prevention Curriculum &amp; Programs &amp; Teachi
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2013
SP  - 357-372
T2  - Journal of the Society for Social Work and Research
TI  - Dropout Prevention and Intervention Programs for Improving School Completion Among School-Aged Children and Youth: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2014-03819-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.5243%2Fjsswr.2013.22&amp;issn=1948-822X&amp;isbn=&amp;volume=4&amp;issue=4&amp;spage=357&amp;pages=&amp;date=2013&amp;title=Journal+of+the+Society+for+Social+Work+and+Research&amp;atitle=Dropout+prevention+and+intervention+programs+for+improving+school+completion+among+school-aged+children+and+youth%3A+A+systematic+review.&amp;aulast=Wilson&amp;pid=%3Cauthor%3EWilson%2C+Sandra+Jo%3C%2Fauthor%3E%3CAN%3E2014-03819-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 4
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Routine iodine supplementation during pregnancy is recommended by leading health authorities worldwide, even in countries where the iodine status of the population is sufficient. 

**OBJECTIVES:** 
We evaluated the efficacy and safety of iodine supplementation during pregnancy or the periconceptional period on the development and growth of children. Secondary outcomes included pregnancy outcome and thyroid function. DESIGN: A systematic review of randomized controlled trials (RCTs) was conducted. PUBMED, MEDLINE, EMBASE, CINAHL, PsycINFO, and Cochrane Central Register of Controlled Trials databases were searched to identify relevant RCTs. 

**RESULTS: **
Fourteen publications that involved 8 trials met the inclusion criteria. Only 2 included trials reported the growth and development of children and clinical outcomes. Iodine supplementation during pregnancy or the periconceptional period in regions of severe iodine deficiency reduced risk of cretinism, but there were no improvements in childhood intelligence, gross development, growth, or pregnancy outcomes, although there was an improvement in some motor functions. None of the remaining 6 RCTs conducted in regions of mild to moderate iodine deficiency reported childhood development or growth or pregnancy outcomes. Effects of iodine supplementation on the thyroid function of mothers and their children were inconsistent. 

**CONCLUSIONS: **
In this review, we highlight a lack of quality evidence of the effect of prenatal or periconceptional iodine supplementation on growth and cognitive function of children. Although contemporary RCTs of iodine supplementation with outcomes addressing childhood development are indicated, conduct of such RCTs may not be feasible in populations where iodine supplementation in pregnancy is widely practiced.
AD  - Zhou,Shao J. Women&#039;s &amp; Children&#039;s Health Research Institute, North Adelaide, Australia (AJA, MM, and SJZ); the School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, Australia (MM); and the FOODplus Research Centre, School of Agriculture, Food and Wine, University of Adelaide, Urrbrae, Australia (AJA, RAG, MM, and SJZ).
AN  - 24025628
AU  - Zhou,
AU  - S.
AU  - J.
AU  - Anderson,
AU  - A.
AU  - J.
AU  - Gibson,
AU  - R.
AU  - A.
AU  - Makrides,
AU  - M.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3945/ajcn.113.065854
DP  - Ovid Technologies
J2  - Am J Clin Nutr
KW  - Child *Child Development/de [Drug Effects] Congenital Hypothyroidism/pc [Prevention &amp; Control] *Dietary Supplements Female Humans *Iodine/ad [Administration &amp; Dosage] Iodine/df [Deficiency] Pregnancy Pregnancy Outcome Randomized Controlled Trials as Top
L1  - internal-pdf://0504029300/Zhou-2013-Effect of iodine supplementation in.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Zhou, Shao J Anderson, Amanda J Gibson, Robert A Makrides, Maria
PY  - 2013
SP  - 1241-54
T2  - American Journal of Clinical Nutrition
TI  - Effect of iodine supplementation in pregnancy on child development and other clinical outcomes: a systematic review of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24025628
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24025628&amp;id=doi:10.3945%2Fajcn.113.065854&amp;issn=0002-9165&amp;isbn=&amp;volume=98&amp;issue=5&amp;spage=1241&amp;pages=1241-54&amp;date=2013&amp;title=American+Journal+of+Clinical+Nutrition&amp;atitle=Effect+of+iodine+supplementation+in+pregnancy+on+child+development+and+other+clinical+outcomes%3A+a+systematic+review+of+randomized+controlled+trials.&amp;aulast=Zhou&amp;pid=%3Cauthor%3EZhou+SJ%3C%2Fauthor%3E%3CAN%3E24025628%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ajcn.nutrition.org/content/98/5/1241.full.pdf
UR  - http://ajcn.nutrition.org/content/98/5/1241.full.pdf
VL  - 98
ER  -
TY  - JOUR
AB  - ** Background ** 
About 47% of preschool children worldwide are anaemic. Daily oral iron supplementation is a commonly recommended intervention for treatment and prevention of anaemia, but the efficacy and safety of iron supplementation programmes is debated. Thus, we systematically reviewed the evidence for benefit and safety of daily iron supplementation in children aged 4-23 months. 

** Methods** 
We searched Scopus and Medline, from inception to Feb 5, 2013, WHO databases, theses repositories, grey literature, and references. Randomised controlled trials that assigned children 4-23 months of age to daily oral iron supplementation versus control were eligible. We calculated mean difference (MD) or standard MD (SMD) for continuous variables, risk ratios for dichotomous data, and rate ratios for rates. We quantified heterogeneity with the I-2 test and synthesised all data with a random-effects model. This review is registered with the International Prospective Register of Systematic Reviews, number CRD42011001208. 

** Findings ** 
Of 9533 citations identified by the search strategy, 49 articles from 35 studies were eligible; these trials included 42 306 children. Only nine studies were judged to be at low risk of bias. In children receiving iron supplements, the risk ratio for anaemia was 0.61 (95% CI 0.50-0.74; 17 studies, n=4825), for iron deficiency was 0.30 (0.15-0.60; nine studies, n=2464), and for iron deficiency anaemia was 0.14 (0.10-0.22; six studies, n=2145). We identified no evidence of difference in mental (MD 1.65, 95% CI -0.63 to 3.94; six studies, n=1093) or psychomotor development (1.05, -1.36 to 3.46; six studies, n=1086). We noted no significant differences in final length or length-for-age, or final weight or weight-for-age. Children randomised to iron had slightly lesser length (SMD -0.83, -1.53 to -0.12; eight studies, n=868) and weight gain (-1.12, -1.19 to -0.33) over the course of the studies. Vomiting (risk ratio 1.38, 95% CI 1.10-1.73) and fever (1.16, 1.02-1.31) were more prevalent in children receiving iron. Interpretation In children aged 4-23 months, daily iron supplementation effectively reduces anaemia. 

However, the adverse effect profile of iron supplements and effects on development and growth are uncertain. Adequately powered trials are needed to establish the non-haematological benefits and risks from iron supplementation in this group.
AD  - [Pasricha, Sant-Rayn] Univ Melbourne, Nossal Inst Global Hlth, Fac Med Dent &amp; Hlth Sci, Carlton, Vic 3010, Australia. [Pasricha, Sant-Rayn; Biggs, Beverley-Ann] Univ Melbourne, Royal Melbourne Hosp, Fac Med Dent &amp; Hlth Sci, Dept Med, Parkville, Vic, Australia. [Pasricha, Sant-Rayn; Hayes, Emily] Monash Med Ctr, Thalassaemia Serv, Clayton, Vic 3168, Australia. [Kalumba, Kongolo] Monash Specialists Womens &amp; Childrens, Clayton, Vic, Australia. Pasricha, SR (reprint author), Univ Melbourne, Nossal Inst Global Hlth, Fac Med Dent &amp; Hlth Sci, Carlton, Vic 3010, Australia. sant-rayn.pasricha@unimelb.edu.au
AN  - WOS:000336422400017
AU  - Pasricha,
AU  - S.
AU  - R.
AU  - Hayes,
AU  - E.
AU  - Kalumba,
AU  - K.
AU  - Biggs,
AU  - B.
AU  - A.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/S2214-109X(13)70046-9
J2  - Lancet Glob. Health
KW  - PLACEBO-CONTROLLED TRIAL ROUTINE PROPHYLACTIC SUPPLEMENTATION DEFICIENT ANEMIC INFANTS BREAST-FED INFANTS ZINC SUPPLEMENTATION INDONESIAN INFANTS YOUNG-CHILDREN PSYCHOMOTOR DEVELOPMENT MICRONUTRIENT STATUS PRESCHOOL-CHILDREN Public, Environmental &amp; Occu
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: AH8XV Times Cited: 7 Cited Reference Count: 58 Pasricha, Sant-Rayn Hayes, Emily Kalumba, Kongolo Biggs, Beverley-Ann 7 ELSEVIER SCI LTD OXFORD LANCET GLOB HEALTH
PY  - 2013
SP  - E77-E86
T2  - Lancet Global Health
TI  - Effect of daily iron supplementation on health in children aged 4-23 months: a systematic review and meta-analysis of randomised controlled trials
UR  - &lt;Go to ISI&gt;://WOS:000336422400017http://ac.els-cdn.com/S2214109X13700469/1-s2.0-S2214109X13700469-main.pdf?_tid=28d555fe-1679-11e5-a498-00000aacb35e&amp;acdnat=1434714713_16b4d7ab0406aae10bd0d5a379b806bd
VL  - 1
ER  -
TY  - JOUR
AB  - **Objective: **
To systematically review and quantitatively evaluate the efficacy of Family-Based Treatment (FBT) compared with individual treatment among adolescents with eating disorders. 

**Method: **
The literature was reviewed using the MEDLINE search terms family therapy AND Anorexia Nervosa, and family therapy AND Bulimia Nervosa. This produced 12 randomized controlled trials involving adolescents with eating disorders and family therapy which were reviewed carefully for several inclusion criteria including: allocation concealment, intent-to-treat analysis, assessor blinding, behavioral family therapy compared with an individual therapy, and adolescent age group. References from these articles were searched. Only three studies met these strict inclusion criteria for meta-analysis. A random effects model and odds ratio was used for meta-analysis, looking at remission as the outcome of choice. 

**Results: **
When combined in a meta-analysis, end of treatment data indicated that FBT was not significantly different from individual treatment (z = 1.62, p = 0.11). However, when follow-up data from 6 to 12 months were analyzed, FBT was superior to individual treatment (z = 2.94, p &lt; 0.003), and heterogeneity was not significant (p = 0.59). 

**Discussion: **
Although FBT does not appear to be superior to individual treatment at end of treatment, there appear to be significant benefits at 612 month follow-up for adolescents suffering from eating disorders. 

(C) 2012 by Wiley Periodicals, Inc. (Int J Eat Disord 2013)
AD  - [Couturier, Jennifer; Szatmari, Peter] McMaster Univ, Dept Psychiat &amp; Behav Neurosci, Hamilton, ON L8N 3Z5, Canada. [Couturier, Jennifer; Szatmari, Peter] McMaster Univ, Dept Pediat, Hamilton, ON L8N 3Z5, Canada. [Couturier, Jennifer; Kimber, Melissa; Szatmari, Peter] McMaster Univ, Dept Clin Epidemiol &amp; Biostat, Hamilton, ON L8N 3Z5, Canada. [Kimber, Melissa; Szatmari, Peter] McMaster Univ, Offord Ctr Child Studies, Hamilton, ON L8N 3Z5, Canada. Couturier, J (reprint author), McMaster Univ, Pediat Eating Disorders Program, McMaster Childrens Hosp, Dept Psychiat &amp; Behav Neurosci, 1200 Main St W, Hamilton, ON L8N 3Z5, Canada. coutur@mcmaster.ca
AN  - WOS:000312300000002
AU  - Couturier,
AU  - J.
AU  - Kimber,
AU  - M.
AU  - Szatmari,
AU  - P.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/eat.22042
J2  - Int. J. Eating Disord.
KW  - adolescents family-based RANDOMIZED CONTROLLED-TRIAL ANOREXIA-NERVOSA INDIVIDUAL THERAPY BULIMIA-NERVOSA CLINICAL-TRIAL REMISSION TERM Psychology, Clinical Nutrition &amp; Dietetics Psychiatry Psychology
L1  - internal-pdf://2761636036/Couturier-2013-Efficacy of family-based treatm.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 053UN Times Cited: 18 Cited Reference Count: 24 Couturier, Jennifer Kimber, Melissa Szatmari, Peter 20 WILEY-BLACKWELL HOBOKEN INT J EAT DISORDER
PY  - 2013
SP  - 3-11
T2  - International Journal of Eating Disorders
TI  - Efficacy of family-based treatment for adolescents with eating disorders: A systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000312300000002http://onlinelibrary.wiley.com/store/10.1002/eat.22042/asset/22042_ftp.pdf?v=1&amp;t=ib3ja2kf&amp;s=2521699b0fdd1b48fd2643ae29768d1decba729e
UR  - http://onlinelibrary.wiley.com/store/10.1002/eat.22042/asset/22042_ftp.pdf?v=1&amp;t=j8yevuff&amp;s=9fad212c5349ae03968af983f8c9822e4fd56bc0
VL  - 46
ER  -
TY  - JOUR
AB  - The current review applied the evidence-based treatment criteria espoused by the Society for Clinical Child and Adolescent Psychology (Silverman &amp; Hinshaw, 2008 ) to specifically evaluate the short-term and longer term efficacy of Cogmed Working Memory Training (CWMT) as a treatment for youth with Attention-Deficit/Hyperactivity Disorder (ADHD). 

Utilizing a systematic literature search, 7 studies that employed the school-age version of CWMT were identified for this review. The data reviewed herein suggest mixed findings regarding the benefit of CWMT for youth with ADHD. Two randomized controlled studies have demonstrated that CWMT led to improvements in neuropsychological outcomes and parent-rated ADHD symptoms relative to wait-list control and placebo treatment conditions. 

Another study demonstrated effects of CWMT relative to a placebo condition on an analog observation of behavior during an academic task, although this study did not find an effect of CWMT on parent-rated ADHD. 

Finally, an additional study utilizing an active comparison control condition did not find incremental benefits of CWMT on parent- or teacher-rated ADHD. 

Critical issues in interpreting existing studies include lack of alignment between demonstrated outcomes and the hypothesized model of therapeutic benefit of CWMT, issues with equivalence of control conditions, and individual differences that may moderate treatment response. 

Collectively, the strengths and limitations of the studies reviewed suggest that CWMT is best defined as a Possibly Efficacious Treatment for youth with ADHD. We suggest future directions for research and conclude with clinical implications of our findings for the treatment of youth with ADHD.
AD  - Chacko,Anil. a Department of Psychology, Queens College , City University of New York.
AN  - 23668397
AU  - Chacko,
AU  - A.
AU  - Feirsen,
AU  - N.
AU  - Bedard,
AU  - A.
AU  - C.
AU  - Marks,
AU  - D.
AU  - Uderman,
AU  - J.
AU  - Z.
AU  - Chimiklis,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15374416.2013.787622
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
KW  - Adolescent Attention Deficit Disorder with Hyperactivity/pp [Physiopathology] *Attention Deficit Disorder with Hyperactivity/th [Therapy] Child *Cognitive Therapy Evidence-Based Medicine Humans *Memory, Short-Term/ph [Physiology] Randomized Controlled T
LA  - English
M3  - Research Support, N.I.H., Extramural Review
N1  - Chacko, Anil Feirsen, Nicole Bedard, Anne-Claude Marks, David Uderman, Jodi Z Chimiklis, Alyssa R34 MH088845 (United States NIMH NIH HHS) R34MH088845 (United States NIMH NIH HHS)
PY  - 2013
SP  - 769-83
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Cogmed Working Memory Training for youth with ADHD: a closer examination of efficacy utilizing evidence-based criteria
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23668397
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23668397&amp;id=doi:10.1080%2F15374416.2013.787622&amp;issn=1537-4416&amp;isbn=&amp;volume=42&amp;issue=6&amp;spage=769&amp;pages=769-83&amp;date=2013&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Cogmed+Working+Memory+Training+for+youth+with+ADHD%3A+a+closer+examination+of+efficacy+utilizing+evidence-based+criteria.&amp;aulast=Chacko&amp;pid=%3Cauthor%3EChacko+A%3C%2Fauthor%3E%3CAN%3E23668397%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/15374416.2013.787622
VL  - 42
ER  -
TY  - JOUR
AB  - A systematic review of primary prevention was conducted for cannabis use outcomes in youth and young adults. The aim of the review was to develop a comprehensive understanding of prevention programming by assessing universal, targeted, uni-modal, and multi-modal approaches as well as individual program characteristics. Twenty-eight articles, representing 25 unique studies, identified from eight electronic databases (EMBASE, MEDLINE, CINAHL, ERIC, PsycINFO, DRUG, EBM Reviews, and Project CORK), were eligible for inclusion. 

Results indicated that primary prevention programs can be effective in reducing cannabis use in youth populations, with statistically significant effect sizes ranging from trivial (0.07) to extremely large (5.26), with the majority of significant effect sizes being trivial to small. 

Given that the preponderance of significant effect sizes were trivial to small and that percentages of statistically significant and non-statistically significant findings were often equivalent across program type and individual components, the effectiveness of primary prevention for cannabis use should be interpreted with caution. Universal multi-modal programs appeared to outperform other program types (i.e, universal uni-modal, targeted multi-modal, targeted unimodal). 

Specifically, universal multi-modal programs that targeted early adolescents (10-13 year olds), utilised non-teacher or multiple facilitators, were short in duration (10 sessions or less), and implemented boosters sessions were associated with large median effect sizes. While there were studies in these areas that contradicted these results, the results highlight the importance of assessing the interdependent relationship of program components and program types. 

Finally, results indicated that the overall quality of included studies was poor, with an average quality rating of 4.64 out of 9. Thus, further quality research and reporting and the development of new innovative programs are required.
AD  - [Norberg, Melissa M.; Kezelman, Sarah; Lim-Howe, Nicholas] Univ New S Wales, Natl Cannabis Prevent &amp; Informat Ctr, Randwick, NSW, Australia. Norberg, MM (reprint author), Univ New S Wales, Natl Cannabis Prevent &amp; Informat Ctr, Randwick, NSW, Australia. m.norberg@unsw.edu.au
AN  - WOS:000314705800035
AU  - Norberg,
AU  - M.
AU  - M.
AU  - Kezelman,
AU  - S.
AU  - Lim-Howe,
AU  - N.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1371/journal.pone.0053187
J2  - PLoS One
KW  - SUBSTANCE-ABUSE PREVENTION HEALTH-RISK BEHAVIORS SCHOOL-BASED PREVENTION AGE-OF-ONSET DRUG PREVENTION FOLLOW-UP MARIJUANA DEPENDENCE USE INITIATION PROJECT ALERT YOUNG-ADULTS Multidisciplinary Sciences
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 086RY Times Cited: 2 Cited Reference Count: 81 Norberg, Melissa M. Kezelman, Sarah Lim-Howe, Nicholas Norberg, Melissa/H-8365-2014 Norberg, Melissa/0000-0001-7840-9007 Department of Health and Aging (DoHA) The authors gratefully acknowledge the Department of Health and Aging (DoHA; http://www.health.gov.au/) for providing funding for the National Cannabis Prevention and Information Centre, and subsequently, the present study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. 3 PUBLIC LIBRARY SCIENCE SAN FRANCISCO PLOS ONE
PY  - 2013
SP  - 15
T2  - Plos One
TI  - Primary Prevention of Cannabis Use: A Systematic Review of Randomized Controlled Trials
UR  - &lt;Go to ISI&gt;://WOS:000314705800035http://www.plosone.org/article/fetchObject.action?uri=info:doi/10.1371/journal.pone.0053187&amp;representation=PDF
VL  - 8
ER  -
TY  - JOUR
AB  - School connectedness has a significant impact on adolescent outcomes, including reducing risk-taking behavior. 

This paper critically examines the literature on school-based programs targeting increased connectedness for reductions in risk taking. 

Fourteen articles describing seven different school-based programs were reviewed. Programs drew on a range of theories to increase school connectedness, and evaluations conducted for the majority of programs demonstrated positive changes in school connectedness, risk behavior, or a combination of the two. 

Many of the reviewed programs involved widespread school system change, however, which is frequently a complex and time-consuming task. 

Future research is needed to examine the extent of intervention complexity required to result in change. This review also showed a lack of consistency in the definitions and measurement of connectedness as well as few mediation analyses testing assumptions of impact on risk-taking behavior through increases in school connectedness. 

Additionally, this review revealed very limited evaluation of the elements of multicomponent programs that are most effective in increasing school connectedness and reducing adolescent risk taking.
AD  - [Chapman, Rebekah L.; Buckley, Lisa; Sheehan, Mary] Queensland Univ Technol, Ctr Accid Res &amp; Rd Safety Queensland CARRS Q, Kelvin Grove, Qld 4059, Australia. [Shochet, Ian] Queensland Univ Technol, Sch Psychol &amp; Counseling, Kelvin Grove, Qld 4059, Australia. Chapman, RL (reprint author), Queensland Univ Technol, Ctr Accid Res &amp; Rd Safety Queensland CARRS Q, 130 Victoria Pk Rd, Kelvin Grove, Qld 4059, Australia. rl.chapman@qut.edu.au
AN  - WOS:000314716900005
AU  - Chapman,
AU  - R.
AU  - L.
AU  - Buckley,
AU  - L.
AU  - Sheehan,
AU  - M.
AU  - Shochet,
AU  - I.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10648-013-9216-4
J2  - Educ. Psychol. Rev.
KW  - School connectedness Adolescent Risk taking Programs RAISING HEALTHY-CHILDREN SOCIAL-DEVELOPMENT DIFFERENTIAL ASSOCIATION ELEMENTARY-SCHOOL ADOLESCENT HEALTH GATEHOUSE PROJECT ATTACHMENT IMPLEMENTATION INTERVENTION COMMUNITIES Psychology, Educational
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 086VP Times Cited: 2 Cited Reference Count: 54 Chapman, Rebekah L. Buckley, Lisa Sheehan, Mary Shochet, Ian 2 SPRINGER/PLENUM PUBLISHERS NEW YORK EDUC PSYCHOL REV
PY  - 2013
SP  - 95-114
T2  - Educational Psychology Review
TI  - School-Based Programs for Increasing Connectedness and Reducing Risk Behavior: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000314716900005http://link.springer.com/article/10.1007%2Fs10648-013-9216-4http://download.springer.com/static/pdf/44/art%253A10.1007%252Fs10648-013-9216-4.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10648-013-9216-4&amp;token2=exp=1435235688~acl=%2Fstatic%2Fpdf%2F44%2Fart%25253A10.1007%25252Fs10648-013-9216-4.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10648-013-9216-4*~hmac=f6d3f294b42dd8393c3e9e842e4c3bf44fe667bb979d974badc72423c4da1ce1
VL  - 25
ER  -
TY  - JOUR
AB  - **Background:** 
Educational and skills-based interventions are often used to prevent relationship and dating violence among young people.

**Objectives:** 
To assess the efficacy of educational and skills-based interventions designed to prevent relationship and dating violence in adolescents and young adults.

**Search methods:** 
We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, CINAHL, PsycINFO, six other databases and a trials register on 7 May 2012. We handsearched the references lists of key articles and two journals (Journal of Interpersonal Violence and Child Abuse and Neglect). We also contacted researchers in the field.

**Selection criteria:** 
Randomised, cluster-randomised and quasi-randomised studies comparing an educational or skills-based intervention to prevent relationship or dating violence among adolescents and young adults with a control.

**Data collection and analysis:** 
Two review authors independently assessed study eligibility and risk of bias. For each study included in the meta-analysis, data were extracted independently by GF and one other review author (either CH, JN, SH or DS). We conducted meta-analyses for the following outcomes: episodes of relationship violence, behaviours, attitudes, knowledge and skills.

**Main results:** 
We included 38 studies (15,903 participants) in this review, 18 of which were cluster-randomised trials (11,995 participants) and two were quasi-randomised trials (399 participants). We included 33 studies in the meta-analyses. We included eight studies (3405 participants) in the meta-analysis assessing episodes of relationship violence. There was substantial heterogeneity (I2 = 57%) for this outcome. The risk ratio was 0.77 (95% confidence interval (CI) 0.53 to 1.13). We included 22 studies (5256 participants) in the meta-analysis assessing attitudes towards relationship violence. The standardised mean difference (SMD) was 0.06 (95% CI -0.01 to 0.15). We included four studies (887 participants) in the meta-analysis assessing behaviour related to relationship violence; the SMD was -0.07 (95% CI -0.31 to 0.16). We included 10 studies (6206 participants) in the meta-analysis assessing knowledge related to relationship violence; the results showed an increase in knowledge in favour of the intervention (SMD 0.44, 95% CI 0.28 to 0.60) but there was substantial heterogeneity (I2 = 52%). We included seven studies (1369 participants) in the meta-analysis assessing skills related to relationship violence. The SMD was 0.03 (95% CI -0.11 to 0.17). None of the included studies assessed physical health, psychosocial health or adverse outcomes. Subgroup analyses showed no statistically significant differences by intervention setting or type of participants. The quality of evidence for all outcomes included in our meta-analysis was moderate due to an unclear risk of selection and detection bias and a high risk of performance bias in most studies.

**Authors&#039; conclusions:** 
Studies included in this review showed no evidence of effectiveness of interventions on episodes of relationship violence or on attitudes, behaviours and skills related to relationship violence. We found a small increase in knowledge but there was evidence of substantial heterogeneity among studies. Further studies with longer-term follow-up are required, and study authors should use standardised and validated measurement instruments to maximise comparability of results.
AN  - CD004534
AU  - Fellmeth,
AU  - G.
AU  - L.
AU  - Heffernan,
AU  - C.
AU  - Nurse,
AU  - J.
AU  - Habibula,
AU  - S.
AU  - Sethi,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD004534.pub3.
KW  - Interpersonal Relations
KW  - Randomized Controlled Trials as Topic
KW  - Violence [prevention &amp; control]
KW  - Adolescent[checkword]
KW  - Humans[checkword]
KW  - Young Adult[checkword]
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Educational and skills-based interventions for preventing relationship and dating violence in adolescents and young adults
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004534.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004534.pub3/asset/CD004534.pdf?v=1&amp;t=iw7jcgii&amp;s=65268bdb83318933238178725ea437e91d73ed08
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Anxiety is a common and impairing problem in children and adolescents with autism spectrum disorder (ASD). There is emerging evidence that cognitive-behavioral therapy (CBT) could reduce anxiety in children with high-functioning ASD. 

**OBJECTIVE: **
To systematically review the evidence of using CBT to treat anxiety in children and adolescents with ASD. Methods for this review were registered with PROSPERO (CRD42012002722). 

**METHODS: **
We included randomized controlled trials published in English in peer-reviewed journals comparing CBT with another treatment, no treatment control, or waitlist control. Two authors independently screened 396 records obtained from database searches and hand searched relevant journals. Two authors independently extracted and reconciled all data used in analyses from study reports. 

**RESULTS: **
Eight studies involving 469 participants (252 treatment, 217 comparison) met our inclusion criteria and were included in meta-analyses. Overall effect sizes for clinician-and parent-rated outcome measures of anxiety across all studies were d = 1.19 and d = 1.21, respectively. Five studies that included child self-report yielded an average d = 0.68 across self-reported anxiety. 

**CONCLUSIONS: **
Parent ratings and clinician ratings of anxiety are sensitive to detecting treatment change with CBT for anxiety relative to waitlist and treatment-as-usual control conditions in children with high-functioning ASD. Clinical studies are needed to evaluate CBT for anxiety against attention control conditions in samples of children with ASD that are well characterized with regard to ASD diagnosis and co-occurring anxiety symptoms.
AD  - [Sukhodolsky, Denis G.; Bloch, Michael H.; Panza, Kaitlyn E.; Reichow, Brian] Yale Univ, Yale Child Study Ctr, New Haven, CT USA. Sukhodolsky, DG (reprint author), Yale Child Study Ctr, 230 South Frontage Rd, New Haven, CT 06520 USA. denis.sukhodolsky@yale.edu
AN  - WOS:000326475000027
AU  - Sukhodolsky,
AU  - D.
AU  - G.
AU  - Bloch,
AU  - M.
AU  - H.
AU  - Panza,
AU  - K.
AU  - E.
AU  - Reichow,
AU  - B.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2013-1193
J2  - Pediatrics
KW  - autism spectrum disorder cognitive-behavior therapy anxiety children adolescents randomized controlled trial meta-analysis PERVASIVE DEVELOPMENTAL DISORDERS RANDOMIZED CONTROLLED-TRIAL SPECTRUM DISORDERS OPEN-LABEL PSYCHIATRIC-DISORDERS REPETITIVE BEHAV
L1  - internal-pdf://1190958877/Sukhodolsky-2013-Cognitive-Behavioral Therapy.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 245PE Times Cited: 3 Cited Reference Count: 77 Sukhodolsky, Denis G. Bloch, Michael H. Panza, Kaitlyn E. Reichow, Brian National Institutes of Health (NIH); [K01 MH079130]; [K23MH091240] Supported in part by grants K01 MH079130 (Dr Sukhodolsky) and K23MH091240 (Dr Bloch). Funded by the National Institutes of Health (NIH). 3 AMER ACAD PEDIATRICS ELK GROVE VILLAGE PEDIATRICS
PY  - 2013
SP  - E1341-E1350
T2  - Pediatrics
TI  - Cognitive-Behavioral Therapy for Anxiety in Children With High-Functioning Autism: A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000326475000027http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813396/pdf/peds.2013-1193.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813396/pdf/peds.2013-1193.pdf
VL  - 132
ER  -
TY  - JOUR
AB  - This meta-analysis used hierarchical linear modeling to examine 115 single-case studies with 343 participants that examined the effectiveness of social skills interventions for individuals with autism spectrum disorder (ASD). 

The average effect size of the included studies was 1.40 (SD = 0.43, 95% CL = 1.32-1.48, N = 115). In the further, several common predictors including intervention length, age and gender of the participants, and study quality indicators (provision of sufficient, in-depth, and replicable information of participants, settings/materials, independent variables, and dependent variables) were not found to mediate the intervention effectiveness. 

Only research design that the study employed was found to impact the intervention effectiveness; the studies using multiple baseline or reversal design had larger effect sizes than studies using other designs. Implications of the results and limitations of this study are discussed.
AD  - Wang,Shin-Yi. Department of Educational Psychology, University of Alberta, 6-102 Education North, Edmonton, AB, T6G6G5, Canada. shinwangw@yahoo.com.tw
AN  - 23212808
AU  - Wang,
AU  - S.
AU  - Y.
AU  - Parrila,
AU  - R.
AU  - Cui,
AU  - Y.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10803-012-1726-2
DP  - Ovid Technologies
J2  - J Autism Dev Disord
KW  - Adolescent Child Child Development Disorders, Pervasive/di [Diagnosis] Child Development Disorders, Pervasive/px [Psychology] *Child Development Disorders, Pervasive/th [Therapy] Child, Preschool *Emotional Intelligence Female Humans Linear Models Male
LA  - English
M3  - Comparative Study Meta-Analysis
N1  - Wang, Shin-Yi Parrila, Rauno Cui, Ying
PY  - 2013
SP  - 1701-16
T2  - Journal of Autism and Developmental Disorders
TI  - Meta-analysis of social skills interventions of single-case research for individuals with autism spectrum disorders: results from three-level HLM
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23212808 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23212808&amp;id=doi:10.1007%2Fs10803-012-1726-2&amp;issn=0162-3257&amp;isbn=&amp;volume=43&amp;issue=7&amp;spage=1701&amp;pages=1701-16&amp;date=2013&amp;title=Journal+of+Autism+%26+Developmental+Disorders&amp;atitle=Meta-analysis+of+social+skills+interventions+of+single-case+research+for+individuals+with+autism+spectrum+disorders%3A+results+from+three-level+HLM.&amp;aulast=Wang&amp;pid=%3Cauthor%3EWang+SY%3C%2Fauthor%3E%3CAN%3E23212808%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10803-012-1726-2http://media.proquest.com/media/pq/classic/doc/2995406651/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Wang%2C+Shin-yi%3BParrila%2C+Rauno%3BCui%2C+Ying&amp;cit%3Atitle=Meta-Analysis+of+Social+Skills+Interventions+of+Single-Case+Research+...&amp;cit%3Apub=Journal+of+Autism+and+Developmental+Disorders&amp;cit%3Avol=43&amp;cit%3Aiss=7&amp;cit%3Apg=1701&amp;cit%3Adate=Jul+2013&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMzEwMzcwODc2ODo5MjUxOTYSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNDg0MDEyCjEzNjc0NTM4MzI6DURvY3VtZW50SW1hZ2VCATBSBk9ubGluZVoCRlRiA1BGVGoKMjAxMy8wNy8wMXIKMjAxMy8wNy8zMXoAggEpUC0xMDAwMjczLTMxMDc1LUNVU1RPTUVSLTEwMDAwMTU3LTExMTUxMTKSAQZPbmxpbmXKAQdFbmROb3Rl0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCKE9TOkVNUy1QZGZEb2NWaWV3QmFzZS1nZXRNZWRpYVVybEZvckl0ZW3KAg9BcnRpY2xlfEZlYXR1cmXSAgFZ4gIBTvICAA%3D%3D&amp;_s=HLOolnLNuIIUzEK6wGMboARaQfc%3D
UR  - https://link.springer.com/article/10.1007%2Fs10803-012-1726-2
VL  - 43
ER  -
TY  - JOUR
AB  - **Background:** 
Bipolar disorder is a mental disorder characterised by episodes of elevated or irritable mood (manic or hypomanic episodes) and episodes of low mood and loss of energy (depressive episodes). Drug treatment is the first-line treatment for acute mania with the initial aim of rapid control of agitation, aggression and dangerous behaviour. Aripiprazole, an atypical antipsychotic, is used in the treatment of mania both as monotherapy and combined with other medicines. The British Association of Psychopharmacology guidelines report that, in monotherapy placebo-controlled trials, the atypical antipsychotics, including aripiprazole, have been shown to be effective for acute manic or mixed episodes.

**Objectives:** 
To assess the efficacy and tolerability of aripiprazole alone or in combination with other antimanic drug treatments, compared with placebo and other drug treatments, in alleviating acute symptoms of manic or mixed episodes. Other objectives include reviewing the acceptability of treatment with aripiprazole, investigating the adverse effects of aripiprazole treatment, and determining overall mortality rates among those receiving aripiprazole treatment.

**Search methods:** 
The Cochrane Depression, Anxiety and Neurosis Group&#039;s Specialised Register (CCDANCTR-Studies and CCDANCTR-References) was searched, all years to 31st July 2013. This register contains relevant randomised controlled trials from: The Cochrane Library (all years), MEDLINE (1950 to date), EMBASE (1974 to date), and PsycINFO (1967 to date). We also searched Bristol-Myers Squibb clinical trials register, the World Health Organization (WHO) trials portal (ICTRP) and ClinicalTrials.gov (to August 2013).

**Selection criteria:** 
Randomised trials comparing aripiprazole versus placebo or other drugs in the treatment of acute manic or mixed episodes.Data collection and analysis: Two review authors independently extracted data, including adverse effect data, from trial reports and assessed bias. The drug manufacturer or the trial authors were contacted for missing data.

**Main results:** 
Ten studies (3340 participants) were included in the review. Seven studies compared aripiprazole monotherapy versus placebo (2239 participants); two of these included a third comparison arm-one study used lithium (485 participants) and the other used haloperidol (480 participants). Two studies compared aripiprazole as an adjunctive treatment to valproate or lithium versus placebo as an adjunctive treatment (754 participants), and one study compared aripiprazole versus haloperidol (347 participants). The overall risk of bias was unclear. A high dropout rate from most trials (&gt; 20% for each intervention in eight of the trials) may have affected the estimates of relative efficacy. Evidence shows that aripiprazole was more effective than placebo in reducing manic symptoms in adults and children/adolescents at three and four weeks but not at six weeks (Young Mania Rating Scale (YMRS); mean difference (MD) at three weeks (random effects) -3.66, 95% confidence interval (CI) -5.82 to -2.05; six studies; N = 1819, moderate quality evidence) - a modest difference. Aripiprazole was compared with other drug treatments in three studies in adults-lithium was used in one study and haloperidol in two studies. No statistically significant differences between aripiprazole and other drug treatments in reducing manic symptoms were noted at three weeks (YMRS MD at three weeks (random effects) 0.07, 95% CI -1.24 to 1.37; three studies; N = 972, moderate quality evidence) or at any other time point up to and including 12 weeks. Compared with placebo, aripiprazole caused more movement disorders, as measured on the Simpson Angus Scale (SAS), on the Barnes Akathisia Scale (BAS) and by participant-reported akathisia (high quality evidence), with more people requiring treatment with anticholinergic medication (risk ratios (random effects) 3.28, 95% CI 1.82 to 5.91; two studies; N = 730, high quality evidence). Aripiprazole also led to more gastrointestinal disturbances (nausea (high quality evidence), and cons i ation) and caused more children/adolescents to have a prolactin level that fell below the lower limit of normal. Significant heterogeneity was present in the meta-analysis of movement disorders associated with aripiprazole and other treatments and was most likely due to the different side effect profiles of lithium and haloperidol. At the three-week time point, meta-analysis was not possible because of lack of data; however, at 12 weeks, haloperidol resulted in significantly more movement disorders than aripiprazole, as measured on the SAS, the BAS and the Abnormal Involuntary Movement Scale (AIMS) and by participant-reported akathisia. By 12 weeks, investigators reported no difference between aripiprazole and lithium (SAS, BAS, AIMS), except in terms of participant-reported akathisia (RR 2.97, 95% CI 1.37 to 6.43; one study; N = 313).

**Authors&#039; conclusions:** 
Aripiprazole is an effective treatment for mania in a population that includes adults, children and adolescents, although its use leads to gastrointestinal disturbances and movement disorders. Comparative trials with medicines other than haloperidol and lithium are few, so the precise place of aripiprazole in therapy remains unclear.
AN  - CD005000
AU  - Brown,
AU  - R.
AU  - Taylor,
AU  - M.
AU  - J.
AU  - Geddes,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd005000
KW  - Antimanic Agents [therapeutic use]
KW  - Antipsychotic Agents [adverse effects] [therapeutic use]
KW  - Aripiprazole
KW  - Bipolar Disorder [drug therapy]
KW  - Drug Therapy, Combination [methods]
KW  - Dyskinesia, Drug-Induced [etiology]
KW  - Haloperidol [therapeutic use]
KW  - Lithium Compounds [therapeutic use]
KW  - Piperazines [adverse effects] [therapeutic use]
KW  - Quinolones [adverse effects] [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Valproic Acid [therapeutic use]
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Aripiprazole alone or in combination for acute mania
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005000.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005000.pub2/asset/CD005000.pdf?v=1&amp;t=iw7iru07&amp;s=16f8f70c567718c39bc4d91d1c7b68ae995e7b47
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** 
To assess whether lithium has a specific preventive effect for suicide and self harm in people with unipolar and bipolar mood disorders.

**DESIGN:** 
Systematic review and meta-analysis.

**DATA SOURCES:** 
Medline, Embase, CINAHL, PsycINFO, CENTRAL, web based clinical trial registries, major textbooks, authors of important papers and other experts in the discipline, and websites of pharmaceutical companies that manufacture lithium or the comparator drugs (up to January 2013).

**INCLUSION CRITERIA:** 
Randomised controlled trials comparing lithium with placebo or active drugs in long term treatment for mood disorders.

**REVIEW METHODS:** 
Two reviewers assessed studies for inclusion and risk of bias and extracted data. The main outcomes were the number of people who completed suicide, engaged in deliberate self harm, and died from any cause.

**RESULTS:**
48 randomised controlled trials (6674 participants, 15 comparisons) were included. Lithium was more effective than placebo in reducing the number of suicides (odds ratio 0.13, 95% confidence interval 0.03 to 0.66) and deaths from any cause (0.38, 0.15 to 0.95). No clear benefits were observed for lithium compared with placebo in preventing deliberate self harm (0.60, 0.27 to 1.32). In unipolar depression, lithium was associated with a reduced risk of suicide (0.36, 0.13 to 0.98) and also the number of total deaths (0.13, 0.02 to 0.76) compared with placebo. When lithium was compared with each active individual treatment a statistically significant difference was found only with carbamazepine for deliberate self harm. Lithium tended to be generally better than the other active comparators, with small statistical variation between the results.

**CONCLUSIONS:** 
Lithium is an effective treatment for reducing the risk of suicide in people with mood disorders. Lithium may exert its antisuicidal effects by reducing relapse of mood disorder, but additional mechanisms should also be considered because there is some evidence that lithium decreases aggression and possibly impulsivity, which might be another mechanism mediating the antisuicidal effect.
AU  - Cipriani,
AU  - A.
AU  - Hawton,
AU  - K.
AU  - Stockton,
AU  - S.
AU  - Geddes,
AU  - J.
AU  - R.
DA  - Jun 27
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmj.f3646
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - *Antimanic Agents/tu [Therapeutic Use]
KW  - Bipolar Disorder/co [Complications]
KW  - *Bipolar Disorder/dt [Drug Therapy]
KW  - Child
KW  - Child, Preschool
KW  - Humans
KW  - *Lithium Compounds/tu [Therapeutic Use]
KW  - Middle Aged
KW  - Randomized Controlled Trials as Topic
KW  - Self-Injurious Behavior/co [Complications]
KW  - *Self-Injurious Behavior/pc [Prevention &amp; Control]
KW  - *Suicide/pc [Prevention &amp; Control]
KW  - Treatment Outcome
KW  - Young Adult
L1  - internal-pdf://3473098543/bmj.f3646.full.pdf
N1  - BMJ. 346:f3646, 2013 Jun 27.Journal ArticleMeta-AnalysisResearch Support, Non-U.S. Gov&#039;tReviewSystematic Review
PY  - 2013
SP  - f3646
TI  - Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis. [Review]
VL  - 1
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
Mentoring has drawn substantial interest from policymakers, intervention theorists, and those interested in identifying promising and useful evidence-based approaches to interventions for criminal justice and child welfare outcomes (Grossman &amp; Tierney, 1998; Jekliek et al., 2002). Mentoring is one of the most commonly-used interventions to prevent, divert, and remediate youth engaged in, or thought to be at risk for, delinquent behavior, school failure, aggression, or other antisocial behavior (DuBois, Holloway, Valentine, &amp; Cooper, 2002, DuBois, Portillo, Rhodes, Silverthorn, &amp; Valentine, 2011). One account lists over 5000 organizations within the United States that use mentoring to promote youth wellbeing and reduce risk (MENTOR/National Mentoring Partnership, 2006). Definitions of mentoring vary, but there are common elements. For the purpose of this review, mentoring was defined by the following 4 characteristics: 1) interaction between two individuals over an extended period of time, 2) inequality of experience, knowledge, or power between the mentor and mentee (recipient), with the mentor possessing the greater share, 3) the mentee is in a position to imitate and benefit from the knowledge, skill, ability, or experience of the mentor, 4) the absence of the role inequality that typifies other helping relationships and is marked by professional training, certification, or predetermined status differences such as parent-child or teacher-student relationships. A total of 46 topic and methodologically eligible studies (out of 164 outcome reports) were identified for inclusion in the meta-analysis on delinquency and outcomes associated to delinquency: aggression, drug use, and academic achievement. 

**OBJECTIVES** 
This systematic review had the following objectives: a) To statistically characterize the evidence to date on the effects of mentoring interventions (selective and indicated) for delinquency (e.g. arrest, reported delinquency), and related problems of aggression drug use, school failure. b) To attempt to clarify the variation in effects of mentoring related to program organization and delivery, study methodology, and participant characteristics. c) To help define mentoring in a more systematic fashion than has occurred to date to, in turn, help clarify how intervention processes suggested as compromising how mentoring has effects and other important considerations for future research.. d) To inform policy about the value of mentoring and the key features for utility. 

**SEARCH STRATEGY** 
This is an update of a review completed 4 years ago. In the original review search we benefitted from the authors of three meta-analyses on mentoring or related topics (1) DuBois et al. (2002) on mentoring in general, 2) Lipsey and Wilson (1998) on delinquency interventions in general, and 3) Aos et al. (2004) on interventions for delinquency and associated social problems) who provided databases on reports and coding approaches. In addition, we searched various databases including PsychINFO, Criminal Justice Abstracts, Criminal Justice Periodicals Index, Social Sciences Citation Index (SSCI), Science Citation Index (SCI), Applied Social Sciences Indexes and Abstracts (ASSIA), MEDLINE, Science Direct, Sociological Abstracts, Dissertation Abstracts, Database of Abstracts of Reviews of Effectiveness, and ERIC (Education Resources Information Center) and the Social, Psychological, Educational and Criminological Trials Register (SPECTR- in original search), the National Research Register (NRR, research in progress), and SIGLE (System for Information on Grey Literature in Europe). Finally, the reference lists of primary studies and reviews in studies identified from the search of electronic resources were scanned for any not-yet identified studies that were relevant to the systematic review. For this update we searched the same databases (except SPECTR as it no longer existed), surveyed pertinent journals and the reference lists of primary studies and reviews. 

**SELECTION CRITERIA** 
1. Studies that focused on youth who were at ri k for juvenile delinquency or who were currently involved in delinquent behavior. Risk is defined as the presence of individual or ecological characteristics that increase the probability of delinquency in later adolescence or adulthood. 2. We included interventions focusing on prevention for those at-risk (selective interventions) and treatment (indicated interventions) that included mentoring as the intervention or one component of the intervention and at least measured impact of the program. We excluded studies in which the intervention was explicitly psychotherapeutic, behavior modification, or cognitive behavioral training and indicated provision of helping services as part of a professional role. 3. We required studies to measure at least one quantitative effect on one of the four outcomes (delinquency, aggression, substance use, academic achievement) in a comparison of mentoring to a control condition. Experimental and high quality quasi-experimental designs were included. 4. The review was limited to studies conducted within the United States or another predominately English-speaking country and reported in English and to studies reported between 1970 and 2011. We did not have resources for translating reports not reported in English. 

**DATA COLLECTION AND ANALYSIS** 
All eligible studies were coded using a protocol derived from three related prior meta-analyses, with 20% double-coded. The intervention effect for each outcome was standardized using well established methods to calculate an effect size with 95% confidence intervals for each of the four outcomes (if included in that study): delinquency, aggression, drug use and academic achievement. Meta-analyses were then conducted for each independent study within a given outcome (delinquency, aggression, drug use, and academic achievement). Effect sizes for each study were scaled so that a positive effect indicated a desirable outcome (i.e., lower delinquency, drug use, and aggression or higher academic achievement). 

**MAIN RESULTS** 
A total of 164 studies were identified as meeting inclusion criteria as focused on delinquency and mentoring. Of these, 46 met the additional criteria for inclusion in the quantitative analyses. 27 were randomized controlled trials and 19 were quasi-experimental studies involving non-random assignment, but with matched comparison groups as was described above. Twenty-five studies reported delinquency outcomes, 25 reported academic achievement outcomes, 6 reported drug use outcomes, and 7 reported aggression outcomes. Main effects sizes were positive and statistically significant for all four outcomes. Some studies showed effects that were not significant and a few reported negative effects. For each outcome there was substantial variation in effect size, too. Average effects were larger for delinquency than for other outcomes. When moderation was tested, there was considerable variation in effect sizes of studies that were similar in regard to the presence of a given moderating influence. We compared effect sizes of those studies that were random assignment experimental designs with those that were quasi-experimental using meta-regression and found no evidence of differences in effect sizes. We conducted moderator analyses to determine whether effects found differed by 1) criteria for selecting participants, 2) presence of other components along with the mentoring intervention, 3) motivation of mentors for participation, or 4) assessment of quality or fidelity of implementation of the intervention. We also conducted moderator analyses to test for outcome differences by the presence or absence of four theorized key components of mentoring interventions. The relatively limited information about potential moderating characteristics extractable from many reports and the limited number of reports with extractable information led us to combine effects across all four outcomes to enable adequate power and in combination to our directional expectations for moderators to test significance using a one-tailed tes (p &lt; .05). For these analyses, we averag d effect sizes within a given study if more than one outcome of interest was reported. We also conducted analyses to check for bias in effects due to type of outcome, and found no suggestion of bias. We found evidence for moderation when professional development was a motive for becoming a mentor. There was also moderation of the effect size when mentoring programs emphasized either of two theorized components: emotional support or advocacy. Effect sizes did not differ by whether or not the program emphasized the other two key components: modeling/identification or teaching, nor by whether other components were used, how risk was defined (environmental versus individual characteristics) or if fidelity/adherence of implementation features were assessed. 

**REVIEWERS&rsquo; CONCLUSIONS** 
This analysis of 46 studies on four outcomes measuring delinquency or closely related outcomes of aggression, drug use, and academic functioning suggests mentoring for high-risk youth has a modest positive effect for delinquency and academic functioning, with trends suggesting similar benefits for aggression and drug use. Effect sizes varied more for delinquency and academic achievement than for aggression and drug use. We did not find a significant difference in effect size by study design (RA vs. QE) or by whether or not fidelity was assessed. We identified some characteristics that moderated effects that provide additional understanding for further studies and program design. Effects tended to be stronger when professional development was an explicit motive for participation of the mentors. Of four processes theorized as comprising the methods of effects in mentoring, we found evidence for significantly larger effects when emotional support and advocacy were emphasized. Although these findings support viewing mentoring as a useful approach for intervention to lessen delinquency risk or involvement, limited description of content of mentoring programs and substantial variation in what is included as part of mentoring efforts detracts from better understanding about what might account for the benefits. The valuable features and most promising approaches cannot be ascertained with any certainty. In fact, the body of studies is remarkably lacking in description of key features, program design organization, and theorized processes of impact that are typically provided in empirical reports of intervention effects. Our judgment is also that there does not seem to be much progression in quality of details in reports over the time period studied here. Given the popularity of this approach, the promise of benefits should be seen as a strong argument for a concerted effort through quality randomized trials to specify the theoretical and practical components for effective mentoring with high-risk youth. Concordantly, lacking such features, further trials may not add useful knowledge.
AU  - Tolan,
AU  - P.
AU  - Henry,
AU  - D.
AU  - Schoeny,
AU  - M.
AU  - Bass,
AU  - A.
AU  - Lovegrove,
AU  - P.
AU  - Nichols,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2013.10
KW  - Aggressiveness
KW  - Drug abuse
KW  - Academic achievement
KW  - Social roles
KW  - Juvenile delinquency
PY  - 2013
T2  - Campbell Systematic Reviews
TI  - Mentoring Interventions to Affect Juvenile Delinquency and Associated Problems: A Systematic Review
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
As the number of individuals diagnosed with autism spectrum disorders (ASD) rises, attention is increasingly focused on potential employment outcomes for individuals with ASD, especially for those individuals that are exiting public school settings. Individuals without disabilities are eight times more likely to be employed than individuals with severe disabilities (National Organization on Disability, 2000). Individuals with ASD are among those least likely to be employed (Cameto, Marder, Wagner, &amp; Cardoso, 2003; Dew &amp; Alan, 2007). Although economic conditions and employer attitudes are important factors in acquiring employment opportunities for individuals with ASD, appropriately addressing specific behaviors common among individuals with ASD can greatly improve employment outcomes (Schaller &amp; Yang, 2005). 

**OBJECTIVE** 
To determine the effectiveness of pre-graduation interventions aimed at persons with autism spectrum disorders to shape behaviors, social interactions, and/or skills that result in employment in mainstream competitive employment settings. 

**SEARCH STRATEGY** 
Studies were identified using electronic search techniques of 30 computerized databases. The keywords used in the computerized bibliography searches were divided into three categories: population, treatment, and domain and design characteristics. The searches covered the period from 1943 through 2011. Grey literature identified through electronic searches was submitted to the same inclusion criteria as other studies. The same time range (1943 - 2011) and inclusion criteria were applied to a search of the grey literature for unpublished studies. References from individual studies were searched for potential studies to consider for inclusion. In addition, unpublished dissertations and theses were identified through the search strategy for review and consideration. 

**SELECTION CRITERIA** 
A two-stage process was used to determine inclusion or exclusion of studies: (1) title and abstract stage and (2) full text stage. The participant sample of the study was secondary school-age individuals (ages 14-22), with a diagnosis of Autism Spectrum Disorder (ASD). Interventions for this review were included if they were designed as an approach to prepare and/or place transition-age individuals with ASD into gainful employment. Interventions that address the acquisition of job-related skills/behaviors or social employment-appropriate skills/behaviors without an employment outcome were excluded. Studies with a research design of randomized controlled trials, quasi-experimental, or single subject experimental were coded for inclusion. 

**DATA COLLECTION AND ANALYSIS** 
The combined electronic and hand searches produced a total of 5,665 citations at Stage 1 Title/Abstract. Of these studies a total of 85 citations were advanced for collection of a full text copy of the study (Full-Text Stage 2). The search results were examined independently by three of the review authors. 

**RESULTS** 
This review was not able to identify definitive interventions that predictably and positively supported the development of transition programs designed to produce employment outcomes for individuals with ASD. Upon review of the full-text for each of the 85 studies, no studies were identified that met all the inclusion criteria specified for the review. The following describes the reasons for exclusion of the studies identified through the Stage 2 review procedures: studies that did not describe or assess an intervention (n = 40), did not present outcomes related with gainful employment (n = 38), did not contain participants with ASD (n = 3), or did not provide quantitative data (case study) (n = 4). 

**AUTHORS&rsquo; CONCLUSIONS**
 While no definitive conclusions can be drawn based upon the current review, the authors did identify qualitative research and other related studies that addressed elements of potential successful employment placements for transition-age individuals with ASD that are detailed in Appendix B. Given the regulations and funding often surrounding transition programming for students with disabilities, it is remarkable that such limited research attention has been paid to the effectiveness of interventions that produce the intended result of such programs. Future research efforts are needed to develop studies that utilize a rigorous experimental design to determine the relative effectiveness of the various interventions being utilized in transition programming for students with ASD. It is also important for such studies to identify actual employment outcomes that result from presumed preparatory or facilitating interventions utilized in transition programs.
AU  - Westbrook,
AU  - J.
AU  - D.
AU  - Fong,
AU  - C.
AU  - J.
AU  - Nye,
AU  - C.
AU  - Williams,
AU  - A.
AU  - Wendt,
AU  - O.
AU  - Cortopassi,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2013.11
PY  - 2013
T2  - Campbell Systematic Reviews
TI  - Pre-Graduation Transition Services for Persons with Autism Spectrum Disorders: Effects on Employment Outcomes
ER  -
TY  - JOUR
AB  - This article reports the findings from a systematic review and meta-analysis of the effects of school dropout prevention programs for pregnant and parenting teens. The meta-analysis synthesized 119 effect sizes from 15 different studies measuring differences in school enrollment and completion outcomes for pregnant and parenting adolescents participating in dropout prevention programs relative to a comparison group. 

The study used random-effects, inverse-variance-weighted meta-analyses with robust variance estimates to synthesize odds ratios for school dropout outcomes. It used mixed-effects meta-regression models to examine the effects of program, methodological, and participant characteristics on program effects. 

The results indicate that drop out programs are effective in reducing school dropout rates and increasing school enrollment rates among teen mothers. Studies using randomized and matched-research designs produced smaller effect sizes than nonrandomized or nonmatched designs and program effects were consistent across different program types and participant samples. 

However, higher levels of implementation quality were associated with larger effects. In general, the results indicate that most school- and community-based programs are effective in decreasing school dropout rates for pregnant or parenting adolescents. 

Cost-effectiveness of programs, fit of services with local needs, and provider capacity are factors that should be considered when implementing the programs. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Steinka-Fry, Katarzyna T.: k.steinkafry@vanderbilt.edu; Wilson, Sandra Jo: sandra.j.wilson@vanderbilt.edu; Tanner-Smith, Emily E.: e.tannersmith@vanderbilt.edu Steinka-Fry, Katarzyna T.: Peabody Research Institute, 230 Appleton Place, PMB 181, Nashville, TN, US, 37203-5721, k.steinkafry@vanderbilt.edu Steinka-Fry, Katarzyna T.: Peabody Research Institute, Vanderbilt University, Nashville, TN, US Wilson, Sandra Jo: Department of Special Education, Vanderbilt University, Nashville, TN, US Tanner-Smith, Emily E.: Peabody Research Institute, Vanderbilt University, Nashville, TN, US
AN  - 2014-03822-001
AU  - Steinka-Fry,
AU  - K.
AU  - T.
AU  - Wilson,
AU  - S.
AU  - J.
AU  - Tanner-Smith
AU  - E.
AU  - E.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.5243/jsswr.2013.23
DP  - Ovid Technologies
KW  - school dropout prevention programs, pregnant adolescents, parenting adolescents, school enrollment, cost effectiveness *Adolescent Pregnancy *Prevention *School Based Intervention *School Dropouts *Parenting Costs and Cost Analysis Curriculum &amp; Programs
LA  - English
M3  - Meta Analysis
PY  - 2013
SP  - 373-389
T2  - Journal of the Society for Social Work and Research
TI  - Effects of School Dropout Prevention Programs for Pregnant and Parenting Adolescents: A Meta-Analytic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2014-03822-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.5243%2Fjsswr.2013.23&amp;issn=1948-822X&amp;isbn=&amp;volume=4&amp;issue=4&amp;spage=373&amp;pages=&amp;date=2013&amp;title=Journal+of+the+Society+for+Social+Work+and+Research&amp;atitle=Effects+of+school+dropout+prevention+programs+for+pregnant+and+parenting+adolescents%3A+A+meta-analytic+review.&amp;aulast=Steinka-Fry&amp;pid=%3Cauthor%3ESteinka-Fry%2C+Katarzyna+T%3C%2Fauthor%3E%3CAN%3E2014-03822-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 4
ER  -
TY  - JOUR
AB  - The purpose of this article is to synthesize the available studies regarding responsive interaction intervention (RII) for children with or at risk for developmental delays with a focus on six dimensions: (a) the characteristics of participants, (b) the features of RII, (c) the measurement of treatment fidelity, (d) the overall effectiveness of RII as reflected by the percentage of studies reporting significant changes in adult or child outcomes, (e) the measurement of maintenance and generalization of RII effects, and (f) the social validity or level of acceptability. 

Through a search of articles from 1990 to 2010, the authors identified 26 studies (31 articles) employing group experimental or quasiexperimental designs incorporating these dimensions. 

Overall, the results of the reviewed studies indicated that implementation of RII resulted in significant positive changes in adults&#039; responsive behaviors and children&#039;s emotional and social-communicative outcomes. 

Although the most frequently reported child outcomes were in the social-communication domain, the most consistently significant positive outcomes for parent and child outcomes were in the emotional domain. 

The authors identify several gaps in this literature and suggest areas where research is needed.
AD  - [Kong, Na Young] Univ Kansas, Lawrence, KS 66045 USA. [Kong, Na Young; Carta, Judith J.] Univ Kansas, Juniper Gardens Childrens Project, Kansas City, KS 66101 USA. Kong, NY (reprint author), Univ Kansas, Juniper Gardens Childrens Project, 444 Minnesota Ave,Suite 300, Kansas City, KS 66101 USA. chellina@ku.edu
AN  - WOS:000317011500001
AU  - Kong,
AU  - N.
AU  - Y.
AU  - Carta,
AU  - J.
AU  - J.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0271121411426486
J2  - Top. Early Child. Spec. Educ.
KW  - responsiveness responsive interaction responsive parenting young children with developmental delays research synthesis PRELINGUISTIC COMMUNICATION INTERVENTIONS RELATIONSHIP-FOCUSED INTERVENTION AUTISM SPECTRUM DISORDERS LANGUAGE IMPAIRMENT EARLY-CHILDH
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 118GD Times Cited: 2 Cited Reference Count: 70 Kong, Na Young Carta, Judith J. 2 SAGE PUBLICATIONS INC THOUSAND OAKS TOP EARLY CHILD SPEC
PY  - 2013
SP  - 4-17
T2  - Topics in Early Childhood Special Education
TI  - Responsive Interaction Interventions for Children With or at Risk for Developmental Delays: A Research Synthesis
UR  - &lt;Go to ISI&gt;://WOS:000317011500001http://tec.sagepub.com/content/33/1/4http://tec.sagepub.com/content/33/1/4.full.pdf
VL  - 33
ER  -
TY  - JOUR
AB  - **Context **
Evidence suggests chronic physical activity (PA) participation may be both protective against the onset of and beneficial for reducing depressive symptoms. 

**Objective **
The aim of this article is to assess the impact of PA interventions on depression in children and adolescents using meta-analysis. 

**Data sources **
Published English language studies were located from manual and computerized searches of the following databases: PsycInfo, The Cochrane Database of Systematic Reviews and The Cochrane Central Register of Controlled Trials, Trials Register of Promoting Health Interventions (TRoPHI; EPPI Centre), Web of Science and MEDLINE. 

**Study selection **
Studies meeting inclusion criteria (1) reported on interventions to promote or increase PA; (2) included children aged 5-11 years and/or adolescents aged 12-19 years; (3) reported on results using a quantitative measure of depression; (4) included a non-physical control or comparison group; and (5) were published in peer-reviewed journals written in English, up to and including May 2011 (when the search was conducted).

**Data extraction **
Studies were coded for methodological, participant and study characteristics. Comprehensive Meta-Analysis version-2 software was used to compute effect sizes, with subgroup analyses to identify moderating characteristics. Study quality was assessed using the Delphi technique. 

**Results **
Nine studies were included (n = 581); most were school-based randomized controlled trials, randomized by individual. Studies used a variety of measurement tools to assess depressive symptoms. The summary treatment effect was small but significant (Hedges&#039; g = -0.26, standard error = 0.09, 95% confidence intervals = -0.43, -0.08, p = 0.004). Subgroup analyses showed that methodological (e.g. studies with both education and PA intervention; those with a higher quality score; and less than 3 months in duration) and participant characteristics (e.g. single-gender studies; those targeting overweight or obese groups) contributed most to the reduction in depression. 

**Conclusions **
There was a small significant overall effect for PA on depression. More outcome-focused, high-quality trials are required to effectively inform the implementation of programmes to reduce depressive symptoms in children and adolescents.
AD  - [Brown, Helen Elizabeth; Brown, Wendy J.; Biddle, Stuart J. H.] Univ Queensland, Sch Human Movement Studies, Brisbane, Qld, Australia. [Pearson, Natalie; Biddle, Stuart J. H.] Loughborough Univ Leicestershire, Sch Sport Exercise &amp; Hlth Sci, Loughborough, Leics, England. [Pearson, Natalie; Biddle, Stuart J. H.] NIHR Leicester Loughborough Diet, Lifestyle &amp; Phys Act Biomed Res Unit, Loughborough, Leics, England. [Braithwaite, Rock E.] Humboldt State Univ, Dept Kinesiol &amp; Recreat Adm, Arcata, CA 95521 USA. Brown, HE (reprint author), Univ Queensland, Sch Human Movement Studies, Brisbane, Qld, Australia. h.brown1@uq.edu.au
AN  - WOS:000318535300004
AU  - Brown,
AU  - H.
AU  - E.
AU  - Pearson,
AU  - N.
AU  - Braithwaite,
AU  - R.
AU  - E.
AU  - Brown,
AU  - W.
AU  - J.
AU  - Biddle,
AU  - S.
AU  - J.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s40279-012-0015-8
J2  - Sports Med.
KW  - CONTROLLED-TRIAL MENTAL-HEALTH PUBLICATION BIAS DOSE-RESPONSE EXERCISE ANXIETY OVERWEIGHT FITNESS FILL Sport Sciences
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 138UK Times Cited: 12 Cited Reference Count: 43 Brown, Helen Elizabeth Pearson, Natalie Braithwaite, Rock E. Brown, Wendy J. Biddle, Stuart J. H. Brown, Wendy/G-2201-2010 Brown, Wendy/0000-0001-9093-4509 Alf Howard International Travel Scholarship (School of Human Movement Studies, University of Queensland); NHMRC [301110] This work was supported by an Alf Howard International Travel Scholarship (School of Human Movement Studies, University of Queensland) that enabled international collaborative work to be undertaken. Helen Elizabeth Brown was partially supported by an Australian NHMRC Program Grant (# 301110). The authors have no conflicts of interest that are directly relevant to the content of this review. 13 ADIS INT LTD AUCKLAND SPORTS MED
PY  - 2013
SP  - 195-206
T2  - Sports Medicine
TI  - Physical Activity Interventions and Depression in Children and Adolescents A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000318535300004http://media.proquest.com/media/pq/classic/doc/3125104471/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Brown%2C+Helen+Elizabeth%3BPearson%2C+Natalie%3BBraithwaite%2C+Rock+E%3BBrown%2C+Wendy+J%3BBiddle%2C+Stuart+J+H&amp;cit%3Atitle=Physical+Activity+Interventions+and+Depression+in+Children+and+...&amp;cit%3Apub=Sports+Medicine&amp;cit%3Avol=43&amp;cit%3Aiss=3&amp;cit%3Apg=195&amp;cit%3Adate=Mar+2013&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMjA2MzQ0MzIxNDoyODMyNzMSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFMzIxOTcyCjE0NTAyNTY0OTI6DURvY3VtZW50SW1hZ2VCATBSBk9ubGluZVoCRlRiA1BGVGoKMjAxMy8wMy8wMXIKMjAxMy8wMy8zMXoAggEpUC0xMDAwMjczLTMxMDc1LUNVU1RPTUVSLTEwMDAwMTU3LTExMTUxMTKSAQZPbmxpbmXKAQdFbmROb3Rl0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCKE9TOkVNUy1QZGZEb2NWaWV3QmFzZS1nZXRNZWRpYVVybEZvckl0ZW3KAiNHZW5lcmFsIEluZm9ybWF0aW9ufEFydGljbGV8RmVhdHVyZdICAVniAgFO8gIA&amp;_s=baSx9K54%2B74q5eYlhZcS%2BlOEssY%3D
UR  - https://link.springer.com/article/10.1007%2Fs40279-012-0015-8
VL  - 43
ER  -
TY  - JOUR
AB  - **Issues **
The use of alcohol and drugs amongst young people is a serious concern and the need for effective prevention is clear. This paper identifies and describes current school-based alcohol and other drug prevention programs facilitated by computers or the Internet. 

**Approach **
The Cochrane Library, PsycINFO and PubMed databases were searched in March 2012. Additional materials were obtained from reference lists of papers. Studies were included if they described an Internet- or computer-based prevention program for alcohol or other drugs delivered in schools. 

**Key Findings **
Twelve trials of 10 programs were identified. Seven trials evaluated Internet-based programs and five delivered an intervention via CD-ROM. The interventions targeted alcohol, cannabis and tobacco. Data to calculate effect size and odds ratios were unavailable for three programs. Of the seven programs with available data, six achieved reductions in alcohol, cannabis or tobacco use at post intervention and/or follow up. Two interventions were associated with decreased intentions to use tobacco, and two significantly increased alcohol and drug-related knowledge. 

**Conclusion **
This is the first study to review the efficacy of school-based drug and alcohol prevention programs delivered online or via computers. Findings indicate that existing computer- and Internet-based prevention programs in schools have the potential to reduce alcohol and other drug use as well as intentions to use substances in the future. These findings, together with the implementation advantages and high fidelity associated with new technology, suggest that programs facilitated by computers and the Internet offer a promising delivery method for school-based prevention.
AD  - [Champion, Katrina E.; Newton, Nicola C.; Barrett, Emma L.; Teesson, Maree] Univ New S Wales, Natl Drug &amp; Alcohol Res Ctr, Sydney, NSW, Australia. Champion, KE (reprint author), 22-32 King St, Randwick, NSW 2052, Australia. k.champion@unsw.edu.au
AN  - WOS:000315853300002
AU  - Champion,
AU  - K.
AU  - E.
AU  - Newton,
AU  - N.
AU  - C.
AU  - Barrett,
AU  - E.
AU  - L.
AU  - Teesson,
AU  - M.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1465-3362.2012.00517.x
J2  - Drug Alcohol Rev.
KW  - prevention school Internet review alcohol RANDOMIZED-CONTROLLED-TRIALS SMOKING PREVENTION DELIVERED INTERVENTIONS SUBSTANCE USE TRANSTHEORETICAL MODEL STUDENT INTERVENTION PROBLEM DRINKING YOUNG-PEOPLE CANNABIS USE ADOLESCENTS Substance Abuse
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 102OG Times Cited: 11 Cited Reference Count: 61 Champion, Katrina E. Newton, Nicola C. Barrett, Emma L. Teesson, Maree 11 WILEY-BLACKWELL HOBOKEN DRUG ALCOHOL REV
PY  - 2013
SP  - 115-123
T2  - Drug and Alcohol Review
TI  - A systematic review of school-based alcohol and other drug prevention programs facilitated by computers or the Internet
UR  - &lt;Go to ISI&gt;://WOS:000315853300002http://onlinelibrary.wiley.com/store/10.1111/j.1465-3362.2012.00517.x/asset/dar517.pdf?v=1&amp;t=ib7voh2r&amp;s=6473a8ad66b28611234ab83b76b7c93386b1cd67
UR  - http://onlinelibrary.wiley.com/doi/10.1111/j.1465-3362.2012.00517.x/abstract
VL  - 32
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
Youth drug use is a severe problem worldwide. This review focuses on a treatment for non-opioid drugs such as cannabis, amphetamines, ecstasy and cocaine, which are strongly associated with a range of health and social problems. Brief Strategic Family Therapy (BSFT) is a manual-based family therapy approach concerned with identifying and ameliorating patterns of interaction in the family system that are presumed to be directly related to the youth&rsquo;s drug usage. BSFT relies primarily on structural family theory (i.e. how the structure of the family influences the youth&rsquo;s behavior) and strategic family theory (i.e. treatment methods are problem-focused and pragmatic). 

**OBJECTIVES** 
The main objectives of this review are to evaluate the current evidence on the effects of BSFT on drug use reduction for young people in treatment for non-opioid drug use and, if possible, to examine moderators of drug use reduction effects to determine whether BSFT works better for particular types of participants. 

**SEARCH STRATEGY** 
An extensive search strategy was used to identify qualifying studies. A wide range of electronic bibliographic databases were searched in June 2011, along with government and policy databanks, grey literature databases, and citations in other reviews. We additionally searched the reference lists of primary studies, hand-searched relevant journals, and searched the Internet using Google. We also maintained a correspondence with researchers within in the field of BSFT. Neither language nor date restrictions were applied to the searches. 

**SELECTION CRITERIA** 
Studies were required to meet several criteria to be eligible for inclusion. Studies must: &bull; have involved a manual-based outpatient BSFT treatment for young people aged 11-21 years enrolled for non-opioid drug use. &bull; have used experimental, quasi-randomized or non-randomized controlled designs. &bull; have reported on at least one of the following eligible outcome variables: drug use frequency, family functioning, education or vocational involvement, treatment retention, risk behavior or any other adverse effect. &bull; not have focused exclusively on treating mental disorders. &bull; have had BSFT as the primary intervention. 

**DATA COLLECTION AND ANALYSIS** 
The literature search yielded a total of 2100 references, of which 58 studies were deemed potentially relevant and retrieved for eligibility determination. Six papers were data-extracted, two of which were subsequently excluded for not focusing on treatment effect. Four papers describing three unique studies were included in the final review. Meta-analysis was used to examine the effects of BSFT on drug use reduction, family functioning and treatment retention compared to Treatment as Usual (TAU) in the included studies, where TAU encompassed a range of conditions and interventions . RESULTS The results of the review should be interpreted with great caution, given the extremely small amount of data available and thus the low statistical power to detect the effects of BSFT. For drug use reduction, there is no evidence that BSFT has an effect on drug use frequency at the end of treatment compared to community treatment programs, group treatment, and minimum contact comparisons3. The random effects standardized mean difference was -0.04 (95% CI -0.25, 0.34), based on three studies with 520 participants. For family functioning, there is no evidence that BSFT has an effect on family functioning at the end of treatment compared to control conditions3. The random effects standardized mean difference was 0.06 (95% CI -0.13, 0.25) for family functioning as reported by parents, based on three studies with 568 participants. The random effects standardized mean difference for family functioning reported by the youth themselves was 0.16 (95% CI -0.19, 0.51), based on two studies with 416 participants. For treatment retention, we found evidence that BSFT may improve treatment retention in young drug users compared to control conditions . The random effects standardized mean difference was 0.55 (95% CI 0.39, 0. 6), bas d on two studies with 606 participants. Meta-analysis was not feasible for the outcome of risk behavior due to differences in the measures used in the individual studies. Horigian et al. (2010) did not report significant effects on risk behavior. Santisteban et al. (2003) used the socialized aggression scale of RBPC, and reported that youth in BSFT intervention showed greater reduction in peer-based delinquency. The random effects standardized mean difference at end of treatment was -0.27 (95% CI -0.72, 0.18). Only Horigian et al. (2010) reported on adverse effects; here more than 50 percent of the young people in the study experienced risk behavior or other adverse events during the trial. The most common event noted was arrest, followed by suspension from or dropping out of school, and absconding from home. However, the distribution of events in both BSFT and control conditions does not indicate clear differences between BSFT and the control conditions. No studies reported on the outcome of education or vocational involvement. We found that the methodological rigor and the adequacy of reporting in the included studies were generally insufficient to allow confident assessment of the effects of BSFT for young drug users. Two of the three included studies provided insufficient information on core issues to allow us to assess the risk of bias (e.g. methods of sequence generation, allocation concealment, and completeness of outcome data). These flaws in methodology have forced us to question the validity of the two studies. Correspondingly, caution should also be placed on any interpretation of the results. Due to the small number of studies included in the review, it was not possible to assess possible moderators of drug use reduction effects. 

**AUTHORS&rsquo; CONCLUSIONS** 
There is insufficient firm evidence to allow conclusions to be drawn on the effect of BSFT on non-opioid drug use in young people. While additional research is needed, there is currently no evidence that BSFT treatment reduces the drug use or improves family functioning for young non-opioid drug users compared to other treatments4. The review provides us with mixed findings: on one hand, BSFT does not seem to have better or worse effects on drug use frequency and family functioning than community treatment programs, group treatment, or minimum contact comparisons, but has positive effects on treatment retention compared to control conditions4, and longer retention in treatment has been identified as a consistent predictor of a favorable outcome from drug use treatment. Although the possibility remains that the length of follow up in the included studies was insufficient to detect significant changes, it should be noted that the evidence we found was limited, both in terms of the number of studies and in their quality. The aim of this systematic review was to explore what is known about the effectiveness of BSFT for reducing drug use in young people who use non-opioid drugs. The information currently available does not provide a sufficient basis for drawing conclusions about actual outcomes and impacts. Consequently, no substantive conclusion about the effectiveness of BSFT can be made, and we can neither support nor reject the BSFT treatment approach examined in this review. There is a need for well-designed randomized controlled trials in this area. New trials should report their results clearly and include long-term follow-up to allow the tracking of effects after treatment cessation.
AU  - Lindstrøm,
AU  - M.
AU  - Rasmussen,
AU  - P.
AU  - S.
AU  - Kowalski,
AU  - K.
AU  - Filges,
AU  - T.
AU  - Jørgensen,
AU  - A.
AU  - M.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2013.7
KW  - Youth
KW  - Drug abuse
KW  - Family therapy
PY  - 2013
T2  - Campbell Systematic Reviews
TI  - Brief Strategic Family Therapy (BSFT) for Young People in Treatment for Non-Opioid Drug Use: A Systematic Review
ER  -
TY  - JOUR
AB  - It has been suggested that working memory training programs are effective both as treatments for attention-deficit/hyperactivity disorder (ADHD) and other cognitive disorders in children and as a tool to improve cognitive ability and scholastic attainment in typically developing children and adults. However, effects across studies appear to be variable, and a systematic meta-analytic review was undertaken. 

To be included in the review, studies had to be randomized controlled trials or quasi-experiments without randomization, have a treatment, and have either a. treated group or an untreated control group. Twenty-three studies with 30 group comparisons met the criteria for inclusion. The studies included involved clinical samples and samples of typically developing children and adults. Meta-analyses indicated that the programs produced reliable short-term improvements in working memory skills. For verbal working memory, these near-transfer effects were not sustained at follow-up, whereas for visuospatial working memory, limited evidence suggested that such effects might be maintained. More importantly, there was no convincing evidence of the generalization of working memory training to other skills (nonverbal and verbal ability, inhibitory processes in attention, word decoding, and arithmetic). 

The authors conclude that memory training programs appear to produce short-term, specific training effects that do not generalize. Possible limitations of the review (including age differences in the samples and the variety of different clinical conditions included) are noted. 

However, current findings cast doubt on both the clinical relevance of working memory training programs and their utility as methods of enhancing cognitive functioning in typically developing children and healthy adults.
AD  - [Melby-Lervag, Monica; Hulme, Charles] Univ Oslo, Dept Special Needs Educ, N-0318 Oslo, Norway. [Hulme, Charles] UCL, Div Psychol &amp; Language Sci, London WC1N 2PF, England. Melby-Lervag, M (reprint author), Univ Oslo, Dept Special Needs Educ, Pb 1140 Blindern, N-0318 Oslo, Norway. monica.melby-lervag@isp.uio.no; c.hulme@ucl.ac.uk
AN  - WOS:000314193900008
AU  - Melby-Lervag,
AU  - M.
AU  - Hulme,
AU  - C.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1037/a0028228
J2  - Dev. Psychol.
KW  - working memory training ADHD attention learning disabilities SHORT-TERM-MEMORY RANDOMIZED CONTROLLED-TRIAL LATENT-VARIABLE APPROACH FLUID INTELLIGENCE SELECTIVE METAANALYSIS EXECUTIVE ATTENTION PUBLICATION BIAS OLDER-ADULTS BRAIN-INJURY FAR TRANSFER Psy
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 079TA Times Cited: 109 Cited Reference Count: 102 Melby-Lervag, Monica Hulme, Charles 113 AMER PSYCHOLOGICAL ASSOC WASHINGTON DEV PSYCHOL
PY  - 2013
SP  - 270-291
T2  - Developmental Psychology
TI  - Is Working Memory Training Effective? A Meta-Analytic Review
UR  - &lt;Go to ISI&gt;://WOS:000314193900008http://psycnet.apa.org/journals/dev/49/2/270.pdf
VL  - 49
ER  -
TY  - JOUR
AB  - **Background: **
In 2009, suicide accounted for 36 897 deaths in the United States. Purpose: To review the accuracy of screening instruments and the efficacy and safety of screening for and treatment of suicide risk in populations and settings relevant to primary care. 

 **Data Sources:  **
Citations from MEDLINE, PsycINFO, the Cochrane Central Register of Controlled Trials, and CINAHL (2002 to 17 July 2012); gray literature; and a surveillance search of MEDLINE for additional screening trials (July to December 2012). Study Selection: Fair-or good-quality English-language studies that assessed the accuracy of screening instruments in primary care or similar populations and trials of suicide prevention interventions in primary or mental health care settings. 

 **Data Extraction:  **
One investigator abstracted data; a second checked the abstraction. Two investigators rated study quality. 

 **Data Synthesis:  **
Evidence was insufficient to determine the benefits of screening in primary care populations; very limited evidence identified no serious harms. Minimal evidence suggested that screening tools can identify some adults at increased risk for suicide in primary care, but accuracy was lower in studies of older adults. Minimal evidence limited to high-risk populations suggested poor performance of screening instruments in adolescents. Trial evidence showed that psychotherapy reduced suicide attempts in high-risk adults but not adolescents. Most trials were insufficiently powered to detect effects on deaths. 

 **Limitation:  **
Treatment evidence was derived from high-risk rather than screening-detected populations. Evidence relevant to adolescents, older adults, and racial or ethnic minorities was limited.

 **Conclusion:  **
Primary care-feasible screening tools might help to identify some adults at increased risk for suicide but have limited ability to detect suicide risk in adolescents. Psychotherapy may reduce suicide attempts in some high-risk adults, but effective interventions for high-risk adolescents are not yet proven.
AD  - Kaiser Permanente Northwest, Portland, OR USA. Univ N Carolina, Sch Med, Chapel Hill, NC 27599 USA. Pharmaceut Res &amp; Manufacturers Amer, Washington, DC 20004 USA. O&#039;Connor, E (reprint author), Kaiser Permanente NW, Ctr Hlth Res, 3800 North Interstate Ave, Portland, OR 97227 USA. elizabeth.oconnor@kpchr.org
AN  - WOS:000319666200017
AU  - O&#039;Connor,
AU  - E.
AU  - Gaynes,
AU  - B.
AU  - N.
AU  - Burda,
AU  - B.
AU  - U.
AU  - Soh,
AU  - C.
AU  - Whitlock,
AU  - E.
AU  - P.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.7326/0003-4819-158-10-201305210-00642
J2  - Ann. Intern. Med.
KW  - RANDOMIZED CONTROLLED-TRIAL DELIBERATE SELF-HARM BORDERLINE PERSONALITY-DISORDER DIALECTICAL BEHAVIOR-THERAPY TERM LITHIUM TREATMENT HIGH-SCHOOL DROPOUTS YOUNG HELP-SEEKERS 5-YEAR FOLLOW-UP COGNITIVE THERAPY MOOD DISORDERS Medicine, General &amp; Internal
L1  - internal-pdf://0262652166/O&#039;Connor-2013-Screening for and Treatment of S.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 154HY Times Cited: 14 Cited Reference Count: 130 O&#039;Connor, Elizabeth Gaynes, Bradley N. Burda, Brittany U. Soh, Clara Whitlock, Evelyn P. Oregon Evidence-based Practice Center [HHS-290-2007-10057-I] Grant Support: By the Oregon Evidence-based Practice Center under contract to AHRQ, Rockville, Maryland (contract HHS-290-2007-10057-I). 14 AMER COLL PHYSICIANS PHILADELPHIA ANN INTERN MED
PY  - 2013
SP  - 741-54
T2  - Annals of Internal Medicine
TI  - Screening for and Treatment of Suicide Risk Relevant to Primary Care: A Systematic Review for the U.S. Preventive Services Task Force
UR  - &lt;Go to ISI&gt;://WOS:000319666200017http://annals.org/data/Journals/AIM/926944/0000605-201305210-00009.pdf
UR  - http://annals.org/data/journals/aim/926944/0000605-201305210-00009.pdf
VL  - 158
ER  -
TY  - JOUR
AB  - **Background:** 
Autism spectrum disorders (ASD) are characterised by abnormalities in social interaction and communication skills, as well as stereotypic behaviours and restricted activities and interests. Selective serotonin reuptake inhibitors (SSRIs) are prescribed for the treatment of conditions often comorbid with ASD such as depression, anxiety and obsessive-compulsive behaviours.

**Objectives:** 
To determine if treatment with an SSRI: 1. improves the core features of autism (social interaction, communication and behavioural problems); 2. improves other non-core aspects of behaviour or function such as self-injurious behaviour; 3. improves the quality of life of adults or children and their carers; 4. has short- and long-term effects on outcome; 5. causes harm.

**Search methods:** 
We searched the following databases up until March 2013: CENTRAL, Ovid MEDLINE, Embase, CINAHL, PsycINFO, ERIC and Sociological Abstracts. We also searched ClinicalTrials.gov and the International Clinical Trials Registry Platform (ICTRP). This was supplemented by searching reference lists and contacting known experts in the field.

**Selection criteria:** 
Randomised controlled trials (RCTs) of any dose of oral SSRI compared with placebo, in people with ASD.

**Data collection and analysis:** 
Two authors independently selected studies for inclusion, extracted data and appraised each study&#039;s risk of bias.

**Main results:** 
Nine RCTs with a total of 320 participants were included. Four SSRIs were evaluated: fluoxetine (three studies), fluvoxamine (two studies), fenfluramine (two studies) and citalopram (two studies). Five studies included only children and four studies included only adults. Varying inclusion criteria were used with regard to diagnostic criteria and intelligence quotient of participants. Eighteen different outcome measures were reported. Although more than one study reported data for Clinical Global Impression (CGI) and obsessive-compulsive behaviour (OCB), different tool types or components of these outcomes were used in each study. As such, data were unsuitable for meta-analysis, except for one outcome (proportion improvement). One large, high-quality study in children showed no evidence of positive effect of citalopram. Three small studies in adults showed positive outcomes for CGI and OCB; one study showed improvements in aggression, and another in anxiety.

**Authors&#039; conclusions:**
There is no evidence of effect of SSRIs in children and emerging evidence of harm. There is limited evidence of the effectiveness of SSRIs in adults from small studies in which risk of bias is unclear.
AN  - CD004677
AU  - Williams,
AU  - K.
AU  - Brignell,
AU  - A.
AU  - Randall,
AU  - M.
AU  - Silove,
AU  - N.
AU  - Hazell,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004677.pub3
KW  - Age Factors
KW  - Autistic Disorder [drug therapy] [psychology]
KW  - Child Development Disorders, Pervasive [drug therapy]
KW  - Citalopram [therapeutic use]
KW  - Fenfluramine [therapeutic use]
KW  - Fluoxetine [therapeutic use]
KW  - Fluvoxamine [therapeutic use]
KW  - Obsessive-Compulsive Disorder [drug therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Serotonin Uptake Inhibitors [therapeutic use]
KW  - Adult[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004677.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004677.pub3/asset/CD004677.pdf?v=1&amp;t=iw7l4x6t&amp;s=c09832f47dbc7c1e7c33095f35e563af898b9f0f
ER  -
TY  - JOUR
AB  - **Objective: **
Brief intervention (BI) is recommended for use with youth who use alcohol and other drugs. Emergency departments (EDs) can provide BIs at a time directly linked to harmful and hazardous use. The objective of this systematic review was to determine the effectiveness of ED-based BIs. 

**Methods: **
We searched 14 electronic databases, a clinical trial registry, conference proceedings, and study references. We included randomized controlled trials with youth 21 years or younger. Two reviewers independently selected studies and assessed methodological quality. One reviewer extracted and a second verified data. We summarized findings qualitatively. 

**Results: **
Two trials with low risk of bias, 2 trials with unclear risk of bias, and 5 trials with high risk of bias were included. Trials evaluated targeted BIs for alcohol-positive (n = 3) and alcohol/other drug-positive youth (n = 1) and universal BIs for youth reporting recent alcohol (n = 4) or cannabis use (n = 1). Few differences were found in favor of ED-based BIs, and variation in outcome measurement and poor study quality precluded firm conclusions for many comparisons. Universal and targeted BIs did not significantly reduce alcohol use more than other care. In one targeted BI trial with high risk of bias, motivational interviewing (MI) that involved parents reduced drinking quantity per occasion and high-volume alcohol use compared with MI that was delivered to youth only. Another trial with high risk of bias reported an increase in abstinence and reduction in physical altercations when youth received peer-delivered universal MI for cannabis use. In 2 trials with unclear risk of bias, MI reduced drinking and driving and alcohol-related injuries after the ED visit. Computer-based MI delivered universally in 1 trial with low risk of bias reduced alcohol-related consequences 6 months after the ED visit. 

**Conclusions: **
Clear benefits of using ED-based BI to reduce alcohol and other drug use and associated injuries or high-risk behaviours remain inconclusive because of variation in assessing outcomes and poor study quality.
AD  - [Newton, Amanda S.; Mabood, Neelam; Ata, Nicole; Ali, Samina; Hartling, Lisa] Univ Alberta, Dept Pediat, Fac Med &amp; Dent, Edmonton, AB T6G 1C9, Canada. [Newton, Amanda S.; Wild, T. Cameron] Univ Alberta, Dept Psychiat, Fac Med &amp; Dent, Edmonton, AB T6G 1C9, Canada. [Dong, Kathryn] Univ Alberta, Fac Med &amp; Dent, Dept Emergency Med, Edmonton, AB T6G 1C9, Canada. [Gokiert, Rebecca] Univ Alberta, Fac Extens, Community Univ Partnership Study Children Youth, Edmonton, AB T6G 1C9, Canada. [Vandermeer, Ben; Tjosvold, Lisa; Hartling, Lisa] Univ Alberta, Alberta Res Ctr Hlth Evidence, Fac Med &amp; Dent, Dept Pediat, Edmonton, AB T6G 1C9, Canada. [Wild, T. Cameron] Univ Alberta, Sch Publ Hlth, Edmonton, AB T6G 1C9, Canada. Newton, AS (reprint author), Univ Alberta, Dept Pediat, Edmonton Clin Hlth Acad, 11405 87 Ave, Edmonton, AB T6G 1C9, Canada. mandi.newton@ualberta.ca
AN  - WOS:000318549400026
AU  - Newton,
AU  - A.
AU  - S.
AU  - Dong,
AU  - K.
AU  - Mabood,
AU  - N.
AU  - Ata,
AU  - N.
AU  - Ali,
AU  - S.
AU  - Gokiert,
AU  - R.
AU  - Vandermeer,
AU  - B.
AU  - Tjosvold,
AU  - L.
AU  - Hartling,
AU  - L.
AU  - Wild,
AU  - T.
AU  - C.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/PEC.0b013e31828ed325
J2  - Pediatr. Emerg. Care
KW  - alcohol use drug use brief intervention adolescent emergency medical services SUBSTANCE USE DISORDERS RANDOMIZED CONTROLLED-TRIAL FOLLOW-UP PRIMARY-CARE MOTIVATIONAL INTERVENTION YOUNG ADULTHOOD BINGE DRINKING CLINICAL-TRIAL ADOLESCENTS ONSET Emergency
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 138YW Times Cited: 3 Cited Reference Count: 71 Newton, Amanda S. Dong, Kathryn Mabood, Neelam Ata, Nicole Ali, Samina Gokiert, Rebecca Vandermeer, Ben Tjosvold, Lisa Hartling, Lisa Wild, T. Cameron Canadian Institutes of Health Research [200805KRS] Funding for this project was provided by a Knowledge Synthesis grant awarded to the principal author from the Canadian Institutes of Health Research (200805KRS). Drs Newton and Hartling hold New Investigator Awards from the Canadian Institutes of Health Research. Dr Wild is a Health Scholar with Alberta Innovates-Health Solutions. 3 LIPPINCOTT WILLIAMS &amp; WILKINS PHILADELPHIA PEDIATR EMERG CARE
PY  - 2013
SP  - 673-684
T2  - Pediatric Emergency Care
TI  - Brief Emergency Department Interventions for Youth Who Use Alcohol and Other Drugs A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000318549400026http://graphics.tx.ovid.com/ovftpdfs/FPDDNCLBFDFJAN00/fs046/ovft/live/gv025/00006565/00006565-201305000-00027.pdf
UR  - https://insights.ovid.com/pubmed?pmid=23640153
VL  - 29
ER  -
TY  - JOUR
AB  - The intervention program for autism known as Treatment and Education of Autistic and Related Communication Handicapped Children (TEACCH) is considered an emerging practice for autism. 

In the present study we used state-of-the-art meta-analytical procedures to examine the pooled clinical effects of TEACCH in a variety of outcomes. 

A total of 13 studies were selected for meta-analysis totaling 172 individuals with autism exposed to TEACCH. Standardized measures of perceptual, motor, adaptive, verbal and cognitive skills were identified as treatment outcomes. We used inverse-variance weighted random effects meta-analysis supplemented with quality assessment, sensitivity analysis, meta-regression, and heterogeneity and publication bias tests. 

The results suggested that TEACCH effects on perceptual, motor, verbal and cognitive skills were of small magnitude in the meta-analyzed studies. Effects over adaptive behavioral repertoires including communication, activities of daily living, and motor functioning were within the negligible to small range. There were moderate to large gains in social behavior and maladaptive behavior. The effects of the TEACCH program were not moderated by aspects of the intervention such as duration (total weeks), intensity (hours per week), and setting (home-based vs. center-based). 

While the present meta-analysis provided limited support for the TEACCH program as a comprehensive intervention, our results should be considered exploratory owing to the limited pool of studies available. 

Copyright &copy; 2013.
AD  - Virues-Ortega,Javier. St.Amant Research Centre &amp; University of Manitoba, P518 Duff Roblin Bldg, 190 Dysart Rd, R3T 2N2 Winnipeg, MB, Canada. Electronic address: javier.virues@ad.umanitoba.ca.
AN  - 23988454
AU  - Virues-Ortega,
AU  - J.
AU  - Julio,
AU  - F.
AU  - M.
AU  - Pastor-Barriuso,
AU  - R.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2013.07.005
DP  - Ovid Technologies
J2  - Clin Psychol Rev
KW  - Autistic Disorder/px [Psychology] *Autistic Disorder/th [Therapy] *Behavior Therapy/mt [Methods] Child Communication Humans Social Behavior Treatment Outcome
LA  - English
M3  - Meta-Analysis
N1  - Virues-Ortega, Javier Julio, Flavia M Pastor-Barriuso, Roberto S0272-7358(13)00093-7
PY  - 2013
SP  - 940-53
T2  - Clinical Psychology Review
TI  - The TEACCH program for children and adults with autism: a meta-analysis of intervention studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23988454 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23988454&amp;id=doi:10.1016%2Fj.cpr.2013.07.005&amp;issn=0272-7358&amp;isbn=&amp;volume=33&amp;issue=8&amp;spage=940&amp;pages=940-53&amp;date=2013&amp;title=Clinical+Psychology+Review&amp;atitle=The+TEACCH+program+for+children+and+adults+with+autism%3A+a+meta-analysis+of+intervention+studies.&amp;aulast=Virues-Ortega&amp;pid=%3Cauthor%3EVirues-Ortega+J%3C%2Fauthor%3E%3CAN%3E23988454%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735813000937/1-s2.0-S0272735813000937-main.pdf?_tid=86ad3218-1972-11e5-a9ce-00000aacb361&amp;acdnat=1435041718_a426cd5b6a6dfd02b6080309dbc831a9
VL  - 33
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Surveys conducted 1998 to 2008 (530,849 13-to 15-year-olds, 100 countries) by the World Health Organization and the Centers for Disease Control and Prevention found increased tobacco use. 

**OBJECTIVES: **
To conduct a systematic review of mentoring to prevent/reduce youth smoking. 

**DATA SOURCES: **
Eight electronic peer-reviewed databases and gray literature searched through January 2013. 

**STUDY ELIGIBILITY CRITERIA, PARTICIPANTS, AND INTERVENTIONS: **
Studies were included if they were randomized controlled trials, included children or adolescents, employed mentoring (consistent companionship, support, guidance to develop youth competence and character), and reported tobacco use. 

**STUDY APPRAISAL/SYNTHESIS METHODS: **
Two reviewers independently assessed abstracts and full-text studies. Disagreements were resolved through consensus. 

**RESULTS: **
Four randomized controlled trials were identified. Two studies focused exclusively on tobacco outcomes; the other 2 reported on both drug and tobacco use reductions. Only 1 study reported that mentoring (by peers) reduced adolescent smoking. Heterogeneity of both participants and outcome measures did not permit meta-analysis. 

**CONCLUSIONS AND IMPLICATIONS OF KEY FINDINGS: **
There is limited literature on this topic. Further research achieving sample sizes required by power computations, minimizing attrition, and ascertaining mentoring content and achievements from mentor and mentee perspectives is needed.
AD  - [Thomas, Roger E.] Dept Family Med, Calgary, AB, Canada. [Lorenzetti, Diane L.] Dept Community Hlth Sci, Calgary, AB, Canada. [Spragins, Wendy] Univ Calgary, Calgary, AB T2N 4N1, Canada. Thomas, RE (reprint author), Univ Calgary, Dept Family Med, Hlth Sci Ctr, G012,3330 Hosp Dr NW, Calgary, AB T2N 4N1, Canada. rthomas@ucalgary.ca
AN  - WOS:000322058600004
AU  - Thomas,
AU  - R.
AU  - E.
AU  - Lorenzetti.
AU  - D.
AU  - L.
AU  - Spragins,
AU  - W.
DA  - Jul-Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.acap.2013.03.008
J2  - Acad. Pediatr.
KW  - adolescents children mentors tobacco use cessation CLUSTER RANDOMIZED-TRIAL COST-BENEFIT-ANALYSIS SMOKING PREVENTION STOP SMOKING INTERVENTION ASSIST YOUTH CESSATION PROGRAMS Pediatrics
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 186QG Times Cited: 1 Cited Reference Count: 31 Thomas, Roger E. Lorenzetti, Diane L. Spragins, Wendy Canadian Tobacco Control Research Initiative Supported in part by a grant from the Canadian Tobacco Control Research Initiative. 1 ELSEVIER SCIENCE INC NEW YORK ACAD PEDIATR
PY  - 2013
SP  - 300-307
T2  - Academic Pediatrics
TI  - Systematic Review of Mentoring to Prevent or Reduce Tobacco Use by Adolescents
UR  - &lt;Go to ISI&gt;://WOS:000322058600004http://ac.els-cdn.com/S1876285913000636/1-s2.0-S1876285913000636-main.pdf?_tid=c0e7ff74-167c-11e5-b71d-00000aab0f6b&amp;acdnat=1434716257_2c1c0ccea1612091d6d07d5fdc678307
VL  - 13
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Nonpharmacological treatments are available for attention deficit hyperactivity disorder (ADHD), although their efficacy remains uncertain. The authors undertook meta-analyses of the efficacy of dietary (restricted elimination diets, artificial food color exclusions, and free fatty acid supplementation) and psychological (cognitive training, neurofeedback, and behavioral interventions) ADHD treatments. 

**METHOD: **
Using a common systematic search and a rigorous coding and data extraction strategy across domains, the authors searched electronic databases to identify published randomized controlled trials that involved individuals who were diagnosed with ADHD (or who met a validated cutoff on a recognized rating scale) and that included an ADHD outcome. 

**RESULTS: **
Fifty-four of the 2,904 nonduplicate screened records were included in the analyses. Two different analyses were performed. When the outcome measure was based on ADHD assessments by raters closest to the therapeutic setting, all dietary (standardized mean differences=0.21-0.48) and psychological (standardized mean differences=0.40-0.64) treatments produced statistically significant effects. However, when the best probably blinded assessment was employed, effects remained significant for free fatty acid supplementation (standardized mean difference=0.16) and artificial food color exclusion (standardized mean difference=0.42) but were substantially attenuated to nonsignificant levels for other treatments. 

**CONCLUSIONS: **
Free fatty acid supplementation produced small but significant reductions in ADHD symptoms even with probably blinded assessments, although the clinical significance of these effects remains to be determined. Artificial food color exclusion produced larger effects but often in individuals selected for food sensitivities. Better evidence for efficacy from blinded assessments is required for behavioral interventions, neurofeedback, cognitive training, and restricted elimination diets before they can be supported as treatments for core ADHD symptoms.
AD  - Sonuga-Barke,Edmund J S. Developmental Brain-Behaviour Laboratory, Department of Psychology, University of Southampton, UK. ejb3@soton.ac.uk
AN  - 23360949
AU  - Sonuga-Barke,
AU  - E.
AU  - J.
AU  - Brandeis,
AU  - D.
AU  - Cortese,
AU  - S.
AU  - Daley,
AU  - D.
AU  - Ferrin,
AU  - M.
AU  - Holtmann,
AU  - M.
AU  - Stevenson,
AU  - J.
AU  - Danckaerts,
AU  - M.
AU  - van
AU  - der
AU  - Oord,
AU  - S.
AU  - Dopfner,
AU  - M.
AU  - Dittmann,
AU  - R.
AU  - W.
AU  - Simonoff,
AU  - E.
AU  - Zuddas,
AU  - A.
AU  - Banaschewski,
AU  - T.
AU  - Buitelaar,
AU  - J.
AU  - Coghill,
AU  - D.
AU  - Hollis,
AU  - C.
AU  - Konofal,
AU  - E.
AU  - Lecendreux,
AU  - M.
AU  - Wong,
AU  - I.
AU  - C.
AU  - Sergeant,
AU  - J.
AU  - European
AU  - ADHD
AU  - Guidelines
AU  - Group
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1176/appi.ajp.2012.12070991
DP  - Ovid Technologies
J2  - Am J Psychiatry
KW  - Adolescent Attention Deficit Disorder with Hyperactivity/di [Diagnosis] Attention Deficit Disorder with Hyperactivity/px [Psychology] *Attention Deficit Disorder with Hyperactivity/th [Therapy] Behavior Therapy *Central Nervous System Stimulants/tu [The
LA  - English
M3  - Comparative Study Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Sonuga-Barke, Edmund J S Brandeis, Daniel Cortese, Samuele Daley, David Ferrin, Maite Holtmann, Martin Stevenson, Jim Danckaerts, Marina van der Oord, Saskia Dopfner, Manfred Dittmann, Ralf W Simonoff, Emily Zuddas, Alessandro Banaschewski, Tobias Buitelaar, Jan Coghill, David Hollis, Chris Konofal, Eric Lecendreux, Michel Wong, Ian C K Sergeant, Joseph European ADHD Guidelines Group Comment in: Evid Based Ment Health. 2013 Aug;16(3):77; PMID: 23704705 Comment in: Am J Psychiatry. 2013 Mar;170(3):241-4; PMID: 23450282 Comment in: Am J Psychiatry. 2013 Jul;170(7):800-2; PMID: 23820834 Comment in: Am J Psychiatry. 2013 Jul;170(7):799-800; PMID: 23820843 Comment in: Am J Psychiatry. 2013 Jul;170(7):799; PMID: 23820833
PY  - 2013
SP  - 275-89
T2  - American Journal of Psychiatry
TI  - Nonpharmacological interventions for ADHD: systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23360949
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23360949&amp;id=doi:10.1176%2Fappi.ajp.2012.12070991&amp;issn=0002-953X&amp;isbn=&amp;volume=170&amp;issue=3&amp;spage=275&amp;pages=275-89&amp;date=2013&amp;title=American+Journal+of+Psychiatry&amp;atitle=Nonpharmacological+interventions+for+ADHD%3A+systematic+review+and+meta-analyses+of+randomized+controlled+trials+of+dietary+and+psychological+treatments.&amp;aulast=Sonuga-Barke&amp;pid=%3Cauthor%3ESonuga-Barke+EJ%3C%2Fauthor%3E%3CAN%3E23360949%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://media.proquest.com/media/pq/classic/doc/2998144411/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Sonuga-Barke%2C+Edmund+JS%3BBrandeis%2C+Daniel%3BCortese%2C+Samuele%3BDaley%2C+David%3BFerrin%2C+Maite%3BHoltmann%2C+Martin%3BStevenson%2C+Jim%3BDanckaerts%2C+Marina%3Bvan+der+Oord%2C+Saskia%3BD%C3%B6pfner%2C+Manfred%3BDittmann%2C+Ralf+W%3BSimonoff%2C+Emily%3BZuddas%2C+Alessandro%3BBanaschewski%2C+Tobias%3BBuitelaar%2C+Jan%3BCoghill%2C+David%3BHollis%2C+Chris%3BKonofal%2C+Eric%3BLecendreux%2C+Michel%3BWong%2C+Ian+CK%3BSergeant%2C+Joseph&amp;cit%3Atitle=Nonpharmacological+Interventions+for+ADHD%3A+Systematic+Review+and+...&amp;cit%3Apub=The+American+Journal+of+Psychiatry&amp;cit%3Avol=170&amp;cit%3Aiss=3&amp;cit%3Apg=275&amp;cit%3Adate=Mar+2013&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYxOTEwMzYyOTY3Njo2NjQ1NzgSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNDA2NjEyCjEzNjg2MDUzODE6DURvY3VtZW50SW1hZ2VCATBSBk9ubGluZVoCRlRiA1BGVGoKMjAxMy8wMy8wMXIKMjAxMy8wMy8zMXoAggEpUC0xMDAwMjczLTMxMDc1LUNVU1RPTUVSLTEwMDAwMTU3LTExMTUxMTKSAQZPbmxpbmXKAQdFbmROb3Rl0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCKE9TOkVNUy1QZGZEb2NWaWV3QmFzZS1nZXRNZWRpYVVybEZvckl0ZW3KAg9BcnRpY2xlfEZlYXR1cmXSAgFZ4gIBTvICAA%3D%3D&amp;_s=VQyWrdT%2FHOLBuSW4krQ6aLiagUM%3D
VL  - 170
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Trichotillomania (TTM) (hair-pulling disorder) is a prevalent and disabling disorder characterised by recurrent hair-pulling. The effect of medication on trichotillomania has not been systematically evaluated. 

**OBJECTIVES: **
To assess the effects of medication for trichotillomania in adults compared with placebo or other active agents. 

**SEARCH METHODS: **
We searched the Cochrane Central Register of Controlled Trials and the Cochrane Depression, Anxiety and Neurosis Group Register (to 31 July 2013), which includes relevant randomised controlled trials from the following bibliographic databases: The Cochrane Library (all years); EMBASE (1974 to date); MEDLINE (1950 to date) and PsycINFO (1967 to date). Two review authors identified relevant trials by assessing the abstracts of all possible studies. 

**SELECTION CRITERIA: **
We selected randomised controlled trials (RCTs) of a medication versus placebo or active agent for TTM in adults. 

**DATA COLLECTION AND ANALYSIS: **
Two review authors independently performed the data extraction and &#039;Risk of bias&#039; assessments, and disagreements were resolved through discussion with a third review author. Primary outcomes included the mean difference (MD) in reduction of trichotillomania symptoms on a continuous measure of trichotillomania symptom severity, and the risk ratio (RR) of the clinical response based on a dichotomous measure, with 95% confidence intervals (CIs). 

**MAIN RESULTS: **
We identified eight studies with a total of 204 participants and a mean sample size of 25. All trials were single-centre trials, and participants seen on an outpatient basis. Seven studies compared medication and placebo (n = 184); one study compared medication and another active agent (n = 13). Duration of the studies was six to twelve weeks. Meta-analysis was not undertaken because of the methodological heterogeneity of the trials. The studies did not employ intention-to-treat analyses and were at a high risk of attrition bias. Adverse events were not well-documented in the studies.None of the three studies of selective serotonin reuptake inhibitors (SSRIs) demonstrated strong evidence of a treatment effect on any of the outcomes of interest. The unpublished naltrexone study did not provide strong evidence of a treatment effect. Two studies, an olanzapine study and a N-acetylcysteine (NAC) study, reported statistically significant treatment effects. One study of clomipramine demonstrated a treatment effect on two out of three measures of response to treatment. 

**AUTHORS&#039; CONCLUSIONS: **
No particular medication class definitively demonstrates efficacy in the treatment of trichotillomania. Preliminary evidence suggests treatment effects of clomipramine, NAC and olanzapine based on three individual trials, albeit with very small sample sizes.
AD  - Department of Psychiatry, University of British Columbia, 2775 Laurel St, Vancouver, British Columbia, Canada, V5Z 1M9.
AN  - 24214100
AU  - Rothbart,
AU  - R.
AU  - Amos,
AU  - T.
AU  - Siegfried,
AU  - N.
AU  - Ipser,
AU  - J.
AU  - C.
AU  - Fineberg,
AU  - N.
AU  - Chamberlain,
AU  - S.
AU  - R.
AU  - Stein,
AU  - D.
AU  - J.
DA  - Nov 8
DB  - Rekoding IN SUM_lme.enl
DO  - 10.1002/14651858.CD007662.pub2
DP  - NLM
J2  - The Cochrane database of systematic reviews
KW  - Acetylcysteine/therapeutic use
KW  - Adult
KW  - Benzodiazepines/therapeutic use
KW  - Clomipramine/therapeutic use
KW  - Humans
KW  - Naltrexone/therapeutic use
KW  - Olanzapine
KW  - Randomized Controlled Trials as Topic
KW  - Serotonin Uptake Inhibitors/therapeutic use
KW  - Trichotillomania/*drug therapy
LA  - eng
N1  - 1469-493xRothbart, RachelAmos, TarynSiegfried, NandiIpser, Jonathan CFineberg, NaomiChamberlain, Samuel RStein, Dan JJournal ArticleResearch Support, Non-U.S. Gov&#039;tReviewSystematic ReviewEnglandCochrane Database Syst Rev. 2013 Nov 8;(11):CD007662. doi: 10.1002/14651858.CD007662.pub2.
PY  - 2013
SP  - Cd007662
T2  - Cochrane Database Syst Rev
TI  - Pharmacotherapy for trichotillomania
UR  - https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD007662.pub2/full
ER  -
TY  - JOUR
AB  - **Background: **
Suicide, in particular among young people, is a major public health problem, although little is known regarding effective interventions for managing and preventing suicide-related behavior. 

**Aims: **
To review the empirical literature pertaining to suicide postvention, prevention, and early intervention, specifically in school settings. 

**Method: **
MEDLINE, PsycINFO, and the Cochrane Central Register of Controlled Trials (CCRCT) as well as citation lists of relevant articles using terms related to suicide and schools were searched in July 2011. School-based programs targeting suicide, attempted suicide, suicidal ideation, and self-harm where intent is not specified were included. No exclusion was placed on trial design. All studies had to include a suicide-related outcome. 

**Results: **
A total of 412 potentially relevant studies were identified, 43 of which met the inclusion criteria, as well as three secondary publications: 15 universal awareness programs, 23 selective interventions, 3 targeted interventions, and 2 postvention trials. 

**Limitations: **
Overall, the evidence was limited and hampered by methodological concerns, particularly a lack of RCTs. 

**Conclusions:** 
The most promising interventions for schools appear to be gatekeeper training and screening programs. However, more research is needed.
AD  - [Robinson, Jo; Cox, Georgina] Univ Melbourne, Orygen Youth Hlth Res Ctr, Melbourne, Vic 3010, Australia. [Robinson, Jo; Cox, Georgina; Williamson, Michelle] Univ Melbourne, Ctr Youth Mental Hlth, Melbourne, Vic 3010, Australia. [Robinson, Jo; Cox, Georgina; Malone, Aisling; Baldwin, Gabriel; Fletcher, Karen; O&#039;Brien, Matt] Headspace Australias Natl Youth Mental Hlth Fdn, Melbourne, Vic, Australia. [Williamson, Michelle] Univ Melbourne, Ctr Hlth Policy Programs &amp; Econ, Sch Populat Hlth, Melbourne, Vic, Australia. Robinson, J (reprint author), Orygen Youth Hlth Res Ctr, 35 Poplar Rd, Parkville, Vic 3052, Australia. jr@uuimelb.edu.au
AN  - WOS:000319715100003
AU  - Robinson,
AU  - J.
AU  - Cox,
AU  - G.
AU  - Malone,
AU  - A.
AU  - Williamson,
AU  - M.
AU  - Baldwin,
AU  - G.
AU  - Fletcher,
AU  - K.
AU  - O&#039;
AU  - Brien,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1027/0227-5910/a000168
J2  - Crisis
KW  - suicide prevention schools systematic review DELIBERATE SELF-HARM YOUTH SUICIDE GENERAL-PRACTITIONERS ADOLESCENT SUICIDE OUTCOME EVALUATION TRAINING-PROGRAM HELP-SEEKING SERVICE USE RISK AWARENESS Psychiatry Psychology, Multidisciplinary
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 154ZL Times Cited: 8 Cited Reference Count: 83 Robinson, Jo Cox, Georgina Malone, Aisling Williamson, Michelle Baldwin, Gabriel Fletcher, Karen O&#039;Brien, Matt 8 HOGREFE &amp; HUBER PUBLISHERS GOTTINGEN CRISIS
PY  - 2013
SP  - 164-182
T2  - Crisis-the Journal of Crisis Intervention and Suicide Prevention
TI  - A Systematic Review of School-Based Interventions Aimed at Preventing, Treating, and Responding to Suicide-Related Behavior in Young People
UR  - &lt;Go to ISI&gt;://WOS:000319715100003
VL  - 34
ER  -
TY  - JOUR
AB  - The present investigation employed meta-analysis to examine the efficacy of cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder (OCD) as well as potential moderators that may be associated with outcome. 

A literature search revealed sixteen randomized-controlled trials (RCTs) with a total sample size of 756 participants that met inclusion criteria. Results indicated that CBT outperformed control conditions on primary outcome measures at post-treatment (Hedges&#039;s g = 1.39) and at follow-up (Hedges&#039;s g = 0.43). Subsequent analyses revealed few moderators of CBT efficacy. Neither higher pre-treatment OCD (p = 0.46) or depression symptom severity (p = 0.68) was significantly associated with a decrease in CBT effect size. Similarly, effect size did not vary as a function of &#039;type&#039; of CBT, treatment format, treatment integrity assessment, blind assessment, age of onset, duration of symptoms, percentage of females, number of sessions, or percent comorbidity. 

However, active treatments showed smaller effect sizes when compared to placebo controls than when compared to waitlist controls. Effect sizes were also smaller for adult RCTs than child RCTs.

Likewise, older age was associated with smaller effect sizes. However, an association between age and effect size was not observed when examining child and adult samples separately. This review indicates that while CBT is efficacious in the treatment of OCD, more research is needed to identify processes that may predict more favorable treatment responses.

Copyright &copy; 2012 Elsevier Ltd. All rights reserved.
AD  - Olatunji,Bunmi O. Department of Psychology, Vanderbilt University, 301 Wilson Hall, 111 21st Avenue South, Nashville, TN 37203, USA. olubunmi.o.olatunji@vanderbilt.edu
AN  - 22999486
AU  - Olatunji,
AU  - B.
AU  - O.
AU  - Davis,
AU  - M.
AU  - L.
AU  - Powers,
AU  - M.
AU  - B.
AU  - Smits,
AU  - J.
AU  - A.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jpsychires.2012.08.020
DP  - Ovid Technologies
J2  - J Psychiatr Res
KW  - *Cognitive Therapy/mt [Methods] Humans *Obsessive-Compulsive Disorder/th [Therapy] Randomized Controlled Trials as Topic/mt [Methods] Treatment Outcome
LA  - English
M3  - Meta-Analysis Review
N1  - Olatunji, Bunmi O Davis, Michelle L Powers, Mark B Smits, Jasper A J S0022-3956(12)00253-1
PY  - 2013
SP  - 33-41
T2  - Journal of Psychiatric Research
TI  - Cognitive-behavioral therapy for obsessive-compulsive disorder: a meta-analysis of treatment outcome and moderators
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22999486
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22999486&amp;id=doi:10.1016%2Fj.jpsychires.2012.08.020&amp;issn=0022-3956&amp;isbn=&amp;volume=47&amp;issue=1&amp;spage=33&amp;pages=33-41&amp;date=2013&amp;title=Journal+of+Psychiatric+Research&amp;atitle=Cognitive-behavioral+therapy+for+obsessive-compulsive+disorder%3A+a+meta-analysis+of+treatment+outcome+and+moderators.&amp;aulast=Olatunji&amp;pid=%3Cauthor%3EOlatunji+BO%3C%2Fauthor%3E%3CAN%3E22999486%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0022395612002531/1-s2.0-S0022395612002531-main.pdf?_tid=81145a50-1677-11e5-8388-00000aab0f02&amp;acdnat=1434714002_eb23bf0563e8a399f7242666ce2ae860
VL  - 47
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The stimulant methylphenidate (MPH) has been a mainstay of treatment for attention-deficit/hyperactivity disorder (ADHD) for many years. Owing to the short half-life and the issues associated with multiple daily dosing of immediate-release MPH formulations, a new generation of long-acting MPH formulations has emerged. Direct head-to-head studies of these long-acting MPH formulations are important to facilitate an evaluation of their comparative pharmacokinetics and efficacy; however, to date, relatively few head-to-head studies have been performed.The objective of this systematic review was to compare the evidence available from head-to-head studies of long-acting MPH formulations and provide information that can guide treatment selection. 

**METHODS: **
A systematic literature search was conducted in MEDLINE and PsycINFO in March 2012 using the MeSH terms: attention deficit disorder with hyperactivity/drug therapy; methylphenidate/therapeutic use and All Fields: Concerta; Ritalin LA; OROS and ADHD; Medikinet; Equasym XL and ADHD; long-acting methylphenidate; Diffucaps and ADHD; SODAS and methylphenidate. No filters were applied and no language, publication date or publication status limitations were imposed. Articles were selected if the title indicated a comparison of two or more long-acting MPH preparations in human subjects of any age; non-systematic review articles and unpublished data were not included. 

**RESULTS: **
Of 15,295 references returned in the literature search and screened by title, 34 articles were identified for inclusion: nine articles from pharmacokinetic studies (nine studies); nine articles from laboratory school studies (six studies); two articles from randomized controlled trials (two studies); three articles from switching studies (two studies) and three articles from one observational study. 

**CONCLUSIONS: **
Emerging head-to-head studies provide important data on the comparative efficacy of the formulations available. At a group level, efficacy across the day generally follows the pharmacokinetic profile of the MPH formulation. No formulation is clearly superior to another; careful consideration of patient needs and subtle differences between formulations is required to optimize treatment. For patients achieving suboptimal symptom control, switching long-acting MPH formulations may be beneficial. When switching formulations, it is usually appropriate to titrate the immediate-release component of the formulation; a limitation of current studies is a focus on total daily dose rather than equivalent immediate-release components. Further studies are necessary to provide guidance in clinical practice, particularly in the treatment of adults and pre-school children and the impact of comorbidities and symptom severity on treatment response.
AD  - Coghill,David. Division of Neuroscience, Medical Research Institute, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK. d.r.coghill@dundee.ac.uk.
AN  - 24074240
AU  - Coghill,
AU  - D.
AU  - Banaschewski,
AU  - T.
AU  - Zuddas,
AU  - A.
AU  - Pelaz,
AU  - A.
AU  - Gagliano,
AU  - A.
AU  - Doepfner,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/1471-244X-13-237
DP  - Ovid Technologies
J2  - BMC Psychiatry
KW  - *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] Central Nervous System Stimulants/ad [Administration &amp; Dosage] *Central Nervous System Stimulants/tu [Therapeutic Use] Child Delayed-Action Preparations Drug Administration Schedule Humans
L1  - internal-pdf://1221532046/Coghill-2013-Long-acting methylphenidate formu.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Coghill, David Banaschewski, Tobias Zuddas, Alessandro Pelaz, Antonio Gagliano, Antonella Doepfner, Manfred
PY  - 2013
SP  - 237
T2  - BMC Psychiatry
TI  - Long-acting methylphenidate formulations in the treatment of attention-deficit/hyperactivity disorder: a systematic review of head-to-head studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24074240 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24074240&amp;id=doi:10.1186%2F1471-244X-13-237&amp;issn=1471-244X&amp;isbn=&amp;volume=13&amp;issue=1&amp;spage=237&amp;pages=237&amp;date=2013&amp;title=BMC+Psychiatry&amp;atitle=Long-acting+methylphenidate+formulations+in+the+treatment+of+attention-deficit%2Fhyperactivity+disorder%3A+a+systematic+review+of+head-to-head+studies.&amp;aulast=Coghill&amp;pid=%3Cauthor%3ECoghill+D%3C%2Fauthor%3E%3CAN%3E24074240%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852277/pdf/1471-244X-13-237.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3852277/pdf/1471-244X-13-237.pdf
VL  - 13
ER  -
TY  - JOUR
AB  - **IMPORTANCE **

Psychostimulant medication is an efficacious treatment for childhood attention-deficit/hyperactivity disorder, yet controversy remains regarding potential iatrogenic effects of stimulant medication, particularly with respect to increasing susceptibility to later substance use disorders. However, stimulant treatment was previously reported to reduce the risk of substance problems. 

**OBJECTIVE **
To meta-analyze the longitudinal association between treatment with stimulant medication during childhood and later substance outcomes (ie, lifetime substance use and substance abuse or dependence). DATA SOURCES Studies published between January 1980 and February 2012 were identified using review articles, PubMed, and pertinent listservs. 

**STUDY SELECTION **
Studies with longitudinal designs in which medication treatment preceded the measurement of substance outcomes. 

**DATA EXTRACTION AND SYNTHESIS **
Odds ratios were extracted or provided by the study authors. Odds ratios were obtained for lifetime use (ever used) and abuse or dependence status for alcohol, cocaine, marijuana, nicotine, and nonspecific drugs for 2565 participants from 15 different studies. 

**MAIN OUTCOMES AND MEASURES **
Random-effects models estimated the overall association, and potential study moderators were examined. 

**RESULTS **
Separate random-effects analyses were conducted for each substance outcome, with the number of studies ranging from 3 to 11 for each outcome. Results suggested comparable outcomes between children with and without medication treatment history for any substance use and abuse or dependence outcome across all substance types. 

**CONCLUSIONS **
These results provide an important update and suggest that treatment of attention-deficit/hyperactivity disorder with stimulant medication neither protects nor increases the risk of later substance use disorders.
AD  - [Humphreys, Kathryn L.; Eng, Timothy; Lee, Steve S.] Univ Calif Los Angeles, Dept Psychiat, Los Angeles, CA USA. Humphreys, KL (reprint author), Univ Calif Los Angeles, Dept Psychol, 1285 Franz Hall,Box 951563, Los Angeles, CA 90095 USA. k.humphreys@ucla.edu; stevelee@psych.ucla.edu
AN  - WOS:000322831100014
AU  - Humphreys,
AU  - K.
AU  - L.
AU  - Eng,
AU  - T.
AU  - Lee,
AU  - S.
AU  - S.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1001/jamapsychiatry.2013.1273
J2  - JAMA Psychiatry
KW  - ATTENTION-DEFICIT/HYPERACTIVITY DISORDER PROSPECTIVE FOLLOW-UP DRUG-USE METHYLPHENIDATE TREATMENT CIGARETTE-SMOKING CONDUCT DISORDER ADHD ABUSE RISK CHILDREN Psychiatry
L1  - internal-pdf://2099111221/Humphreys-2013-Stimulant Medication and Substa.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 197EA Times Cited: 18 Cited Reference Count: 50 Humphreys, Kathryn L. Eng, Timothy Lee, Steve S. National Institutes of Health [1R03AA020186] Dr Lee&#039;s role in this study was supported by grant 1R03AA020186 from the National Institutes of Health. 18 AMER MEDICAL ASSOC CHICAGO JAMA PSYCHIAT
PY  - 2013
SP  - 740-749
T2  - Jama Psychiatry
TI  - Stimulant Medication and Substance Use Outcomes A Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000322831100014http://archpsyc.jamanetwork.com/data/Journals/PSYCH/927231/yoi130063.pdf
UR  - https://jamanetwork.com/journals/jamapsychiatry/articlepdf/1691781/yoi130063.pdf
VL  - 70
ER  -
TY  - JOUR
AB  - Evidence-based interventions are often unavailable in everyday clinical settings. This may partly reflect practitioners&#039; assumptions that research evidence does not reflect &quot;real-world&quot; conditions. 

To examine this further, we systematically assessed the clinical effectiveness of parent management training (PMT) for the treatment of child disruptive behavior across different real-world practice contexts. 

We identified 28 relevant randomized controlled trials from a systematic search of electronic bibliographic databases and conducted a meta-analysis of child outcomes across trials. Planned subgroup analyses involved comparisons between studies grouped according to individual real-world practice criteria and total real-world practice criteria scores, reflecting the extent to which PMT was delivered by non-specialist therapists, to a clinic-referred population, in a routine setting, and as part of a routine service. 

Meta-analysis revealed a significant overall advantage for PMT compared with waitlist control conditions. Subgroup analyses did not demonstrate significant differences in effect size estimates according to the total number of real-world practice criteria met by studies. Moreover, no consistent relationships were found between specific practice criteria and effect size estimates. In conclusion, PMT appears to be an effective treatment for children with disruptive behavior problems. 

There was no clear evidence that conducting PMT in real-world practice contexts is a deterrent to achieving effective child behavior outcomes, although relative advantage to &quot;usual care&quot; was not directly examined and the power of the analysis was limited as a result of significant heterogeneity. 

More research is needed to investigate whether this finding is generalizable to other psychological interventions. Suggestions are also made for developing more differentiated criteria to assist with evaluating the specific applicability of research evidence to different care providers.
AD  - [Michelson, Daniel; Day, Crispin] Kings Coll London, Inst Psychiat, Dept Psychol, London WC2R 2LS, England. [Davenport, Clare; Dretzke, Janine] Univ Birmingham, Dept Publ Hlth Biostat &amp; Epidemiol, Birmingham, W Midlands, England. [Barlow, Jane] Univ Warwick, Warwick Med Sch, Hlth Sci Res Inst, Coventry CV4 7AL, W Midlands, England. Michelson, D (reprint author), Kings Coll London, Inst Psychiat, Dept Psychol, London WC2R 2LS, England. daniel.m.d.michelson@kcl.ac.uk
AN  - WOS:000316018000002
AU  - Michelson,
AU  - D.
AU  - Davenport,
AU  - C.
AU  - Dretzke,
AU  - J.
AU  - Barlow,
AU  - J.
AU  - Day,
AU  - C.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10567-013-0128-0
J2  - Clin. Child Fam. Psychol. Rev.
KW  - Child disruptive behavior Parent management training Meta-analysis Systematic review RANDOMIZED CONTROLLED-TRIAL PSYCHOTHERAPY OUTCOME RESEARCH ONSET CONDUCT PROBLEMS FAMILY INTERVENTION YOUNG-CHILDREN TRIPLE-P ANTISOCIAL-BEHAVIOR CLINICAL-TRIALS MENTAL
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 104TM Times Cited: 8 Cited Reference Count: 93 Michelson, Daniel Davenport, Clare Dretzke, Janine Barlow, Jane Day, Crispin 8 SPRINGER/PLENUM PUBLISHERS NEW YORK CLIN CHILD FAM PSYCH
PY  - 2013
SP  - 18-34
T2  - Clinical Child and Family Psychology Review
TI  - Do Evidence-Based Interventions Work When Tested in the &quot;Real World?&quot; A Systematic Review and Meta-analysis of Parent Management Training for the Treatment of Child Disruptive Behavior
UR  - &lt;Go to ISI&gt;://WOS:000316018000002
UR  - https://link.springer.com/article/10.1007%2Fs10567-013-0128-0
VL  - 16
ER  -
TY  - JOUR
AB  - The purpose of this integrative review is to describe, compare, and synthesize traditional and computer-based family interventions that aim to change adolescents&#039; risky sexual behaviors and substance abuse. 

Family interventions have been shown to generate protective effects for preventing adolescents from risky behaviors. It is not clear, however, whether there are significant differences or similarities in the designs and effects of traditional and computer-based family interventions. 

An integrative literature review was conducted to describe and compare the designs and effects of traditional and computer-based family interventions. 

Both interventions have generated significant effects on reducing risky behavior among adolescents. Interventions guided by theory, tailored to participants&#039; culture/gender, and which included sufficient boosting dosages in their designs demonstrated significant short- or long-term effects in terms of reducing adolescents&#039; risky behaviors. 

Regardless of delivery method, well-designed family interventions are noted to maximize familial protective effects and reduce risky behaviors.
AD  - [Kao, Tsui-Sui; Gibbs, Marilyn Beth; Clemen-Stone, Susan; Duffy, Sonia] Univ Michigan, Ann Arbor, MI 48109 USA. Kao, TS (reprint author), Univ Michigan, Sch Nursing, 400 N Ingalls,Room 3347, Ann Arbor, MI 48109 USA. anniekao@umich.edu
AN  - WOS:000325472500005
AU  - Kao,
AU  - T.
AU  - S.
AU  - Gibbs,
AU  - M.
AU  - B.
AU  - Clemen-Stone,
AU  - S.
AU  - Duffy,
AU  - S.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0193945912465021
J2  - West. J. Nurs. Res.
KW  - parenting families population focus sexuality health behavior symptom focus adolescence PARENT-CHILD COMMUNICATION RANDOMIZED-TRIAL AFRICAN-AMERICAN PREVENTION PROGRAM UNITED-STATES SUBSTANCE USE BASE-LINE HEALTH YOUTH REDUCTION Nursing
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 232ED Times Cited: 3 Cited Reference Count: 37 Kao, Tsui-Sui Gibbs, Marilyn Beth Clemen-Stone, Susan Duffy, Sonia 3 SAGE PUBLICATIONS INC THOUSAND OAKS WESTERN J NURS RES
PY  - 2013
SP  - 611-637
T2  - Western Journal of Nursing Research
TI  - A Comparison of Family Interventions to Address Adolescent Risky Behaviors: A Literature Review
UR  - &lt;Go to ISI&gt;://WOS:000325472500005http://wjn.sagepub.com/content/35/5/611.longhttp://wjn.sagepub.com/content/35/5/611.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/0193945912465021?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 35
ER  -
TY  - JOUR
AB  - A systematic review and meta-analysis of available randomized controlled trials (RCTs) was conducted to evaluate the effect of zinc (Zn) intake on mental and motor development in infants. 

Out of 5500 studies identified through electronic searches and reference lists, 5 RCTs were selected after applying the exclusion/inclusion criteria. The influence of Zn intake on mental and motor development was considered in the overall meta-analysis. 

Other variables were also taken into account as possible effect modifiers: doses of Zn intake, intervention duration, nutritional situation, and risk of bias. Indices of mental and motor development assessed were the Mental Development Index (MDI) and Psychomotor Development Index (PDI). 

Additionally we carried out a sensitivity analysis. The pooled beta was -0.01 (95 %CI -0.02, 0) for MDI and 0 (95 %CI -0.03, 0.02) for PDI, with a substantial heterogeneity in both analyses. When we performed a meta-regression, the effect of Zn supplementation on MDI changed depending on the dose of supplementation. Regarding PDI, there was a differential effect of Zn intake depending on intervention duration, dose of supplementation, nutritional situation, and risk of bias. Zn supplementation showed a negative, weak and significant effect on PDI score in those studies with a length of 4 to 20 weeks (beta= -0.05; CI 95 % -0.06 to -0.04). 

In conclusion, no association was found between Zn intake and mental and motor development in infants. Further standardized research is urgently needed to clarify the role of Zn supplementation upon infant mental and motor development, particularly in Europe.
AD  - Nissensohn,Mariela. Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Spain, and Ciber Fisiopatologia Obesidad y Nutricion (CIBEROBN, CB06/03), Instituto de Salud Carlos III, Madrid, Spain. Sanchez-Villegas,Almudena. Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Spain, and Ciber Fisiopatologia Obesidad y Nutricion (CIBEROBN, CB06/03), Instituto de Salud Carlos III, Madrid, Spain. Fuentes Lugo,Daniel. Faculty of Health Sciences, Unacar, Ciudad del Carmen, Mexico. Henriquez Sanchez,Patricia. Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Spain, and Ciber Fisiopatologia Obesidad y Nutricion (CIBEROBN, CB06/03), Instituto de Salud Carlos III, Madrid, Spain. Doreste Alonso,Jorge. Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Spain, and Ciber Fisiopatologia Obesidad y Nutricion (CIBEROBN, CB06/03), Instituto de Salud Carlos III, Madrid, Spain. Skinner,Anna L. International Institute of Nutritional Sciences and Food Safety Studies, University of Central Lancashire, Preston, UK. Medina,Marisol W. International Institute of Nutritional Sciences and Food Safety Studies, University of Central Lancashire, Preston, UK. Lowe,Nicola M. International Institute of Nutritional Sciences and Food Safety Studies, University of Central Lancashire, Preston, UK. Hall Moran,Victoria. Maternal &amp; Infant Nutrition &amp; Nurture Unit, University of Central Lancashire, Preston, UK. Serra-Majem,Lluis. Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Spain, and Ciber Fisiopatologia Obesidad y Nutricion (CIBEROBN, CB06/03), Instituto de Salud Carlos III, Madrid, Spain.
AN  - 25008010
AU  - Nissensohn,
AU  - M.
AU  - Sanchez-Villegas,
AU  - A.
AU  - Fuentes
AU  - Lugo,
AU  - D.
AU  - Henriquez
AU  - Sanchez,
AU  - P.
AU  - Doreste
AU  - Alonso,
AU  - J.
AU  - Skinner,
AU  - A.
AU  - L.
AU  - Medina,
AU  - M.
AU  - W.
AU  - Lowe,
AU  - N.
AU  - M.
AU  - Hall
AU  - Moran,
AU  - V.
AU  - Serra-Majem,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1024/0300-9831/a000161
DP  - Ovid Technologies
J2  - Int J Vitam Nutr Res
KW  - Brain/gd [Growth &amp; Development] *Child Development/de [Drug Effects] Child Development/ph [Physiology] Cognition/ph [Physiology] *Diet Dietary Supplements Europe Humans Infant Motor Skills/ph [Physiology] Psychomotor Performance/ph [Physiology] Randomiz
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Nissensohn, Mariela Sanchez-Villegas, Almudena Fuentes Lugo, Daniel Henriquez Sanchez, Patricia Doreste Alonso, Jorge Skinner, Anna L Medina, Marisol W Lowe, Nicola M Hall Moran, Victoria Serra-Majem, Lluis
PY  - 2013
SP  - 203-15
T2  - International Journal for Vitamin and Nutrition Research
TI  - Effect of zinc intake on mental and motor development in infants: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=25008010 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:25008010&amp;id=doi:10.1024%2F0300-9831%2Fa000161&amp;issn=0300-9831&amp;isbn=&amp;volume=83&amp;issue=4&amp;spage=203&amp;pages=203-15&amp;date=2013&amp;title=International+Journal+for+Vitamin+%26+Nutrition+Research&amp;atitle=Effect+of+zinc+intake+on+mental+and+motor+development+in+infants%3A+a+meta-analysis.&amp;aulast=Nissensohn&amp;pid=%3Cauthor%3ENissensohn+M%3C%2Fauthor%3E%3CAN%3E25008010%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://econtent.hogrefe.com/doi/abs/10.1024/0300-9831/a000161?url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org&amp;rfr_dat=cr_pub%3Dpubmed&amp;
VL  - 83
ER  -
TY  - JOUR
AB  - Governments, schools, and curriculum authorities are increasingly recognizing that body image during adolescence is a public health issue that warrants attention in the school setting. 

After 30 years of eating disorder prevention research, and given the current interest in this area, it seems timely to review the research on interventions to improve body image in schools. 

We reviewed universal-selective, classroom-based programs that have been conducted since the year 2000, among adolescents, and found 16 eligible intervention programs. 

Seven of these programs were effective in improving body image on at least one measure, from pre to post test, though effect sizes were small (d = 0.22-0.48). 

These effective programs were conducted among younger adolescents 12.33-13.62 years, and included activities focusing on media literacy, self esteem, and the influence of peers. 

Implications for school personnel and curriculum authorities are discussed, and we provide recommendations for a strategic approach to future research in this area. 

(c) 2013 Elsevier Ltd. All rights reserved.
AD  - [Yager, Zali] La Trobe Univ, Fac Educ, Bendigo, Vic 3550, Australia. [Yager, Zali; Diedrichs, Phillippa C.; Halliwell, Emma] Univ W England, Fac Hlth &amp; Life Sci, Ctr Appearance Res, Bristol BS16 1QY, Avon, England. [Ricciardelli, Lina A.] Deakin Univ, Sch Psychol, Burwood, Vic 3125, Australia. Yager, Z (reprint author), La Trobe Univ, Fac Educ, Edwards Rd, Bendigo, Vic 3550, Australia. z.yager@latrobe.edu.au
AN  - WOS:000321088000001
AU  - Yager,
AU  - Z.
AU  - Diedrichs,
AU  - P.
AU  - C.
AU  - Ricciardelli,
AU  - L.
AU  - A.
AU  - Halliwell,
AU  - E.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.bodyim.2013.04.001
J2  - Body Image
KW  - Body image Schools Intervention Prevention Adolescents DISORDER PREVENTION PROGRAM WEIGHT-CONTROL BEHAVIORS MEDIA LITERACY PROGRAM EARLY ADOLESCENT GIRLS EATING-DISORDERS RISK-FACTORS SELF-ESTEEM APPEARANCE QUESTIONNAIRE SOCIOCULTURAL ATTITUDES FEMALE A
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 173OE Times Cited: 5 Cited Reference Count: 117 Yager, Zali Diedrichs, Phillippa C. Ricciardelli, Lina A. Halliwell, Emma 5 ELSEVIER SCIENCE BV AMSTERDAM BODY IMAGE
PY  - 2013
SP  - 271-281
T2  - Body Image
TI  - What works in secondary schools? A systematic review of classroom-based body image programs
UR  - &lt;Go to ISI&gt;://WOS:000321088000001http://ac.els-cdn.com/S1740144513000405/1-s2.0-S1740144513000405-main.pdf?_tid=203a10be-18b4-11e5-91fc-00000aacb361&amp;acdnat=1434959942_7cca4d9a8b853253f2e59624f5b0d5de
VL  - 10
ER  -
TY  - JOUR
AB  - **Background:** 
Postnatal depression is a medical condition that affects many women and the development of their infants. There is a lack of evidence for treatment and prevention strategies that are safe for mothers and infants. Certain dietary deficiencies in a pregnant or postnatal woman&#039;s diet may cause postnatal depression. By correcting these deficiencies postnatal depression could be prevented in some women. Specific examples of dietary supplements aimed at preventing postnatal depression include: omega-3 fatty acids, iron, folate, s-adenosyl-L-methionine, cobalamin, pyridoxine, riboflavin, vitamin D and calcium.

**Objectives:** To assess the benefits of dietary supplements for preventing postnatal depression either in the antenatal period, postnatal period, or both.

**Search methods:** 
We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (30 April 2013).

**Selection criteria:** 
Randomised controlled trials, involving women who were pregnant or who had given birth in the previous six weeks, who were not depressed or taking antidepressants at the commencement of the trials. The trials could use as intervention any dietary supplementation alone or in combination with another treatment compared with any other preventive treatment, or placebo, or standard clinical care.

**Data collection and analysis:** 
Two review authors independently assessed trials for inclusion and assessed the risk of bias for the two included studies. Two review authors extracted data and the data were checked for accuracy.

**Main results:** 
We included two randomised controlled trials.One trial compared oral 100 microgram (&micro;g) selenium yeast tablets with placebo, taken from the first trimester until birth. The trial randomised 179 women but outcome data were only provided for 85 women. Eighty-three women were randomised to each arm of the trial. Sixty-one women completed the selenium arm, 44 of whom completed an Edinburgh Postnatal Depression Scale (EPDS). In the placebo arm, 64 women completed the trial, 41 of whom completed an EPDS. This included study (n = 85) found selenium had an effect on EPDS scores but did not reach statistical significance (P = 0.07). There was a mean difference (MD) of -1.90 (95% confidence interval (CI) -3.92 to 0.12) of the self-reported EPDS completed by participants within eight weeks of delivery. There was a high risk of attrition bias due to a large proportion of women withdrawing from the study or not completing an EPDS. This included study did not report on any of the secondary outcomes of this review.The other trial compared docosahexanoic acid (DHA) and eicosapentaenoic acid (EPA) with placebo. The trial randomised 126 women at risk of postpartum depression to three arms: 42 were allocated to EPA, 42 to DHA, and 42 to placebo. Three women in the EPA arm, four in the DHA arm, and one woman in the placebo arm were lost to follow-up. Women who were found to have major depressive disorder, bipolar disorder, current substance abuse or dependence, suicidal ideation or schizophrenia at recruitment were excluded from the study. The women who discontinued the intervention (five in the EPA arm, four in the DHA arm and seven in the placebo arm) were included in the intention-to-treat analysis, while those who were lost to follow-up were not. Women received supplements or placebo from recruitment at a gestational age of 12 to 20 weeks until their final review visit six to eight weeks postpartum. The primary outcome measure was the Beck Depression Inventory (BDI) score at the fifth visit (six to eight weeks postpartum). No benefit was found for EPA-rich fish oil (MD 0.70, 95% CI -1.78 to 3.18) or DHA-rich fish oil supplementation (MD 0.90, 95% CI -1.33 to 3.13) in preventing postpartum depression. No difference was found in the effect on postnatal depression comparing EPA with DHA (MD -0.20, 95% CI -2.61 to 2.21). No benefit or significant effect was found in terms of the secondary outcomes of the presence of major depressive disorder at six to eight weeks postpartum, the number of women who commenced antidepressants, mate n l estimated blood loss at delivery or admission of neonates to the neonatal intensive care unit.

**Authors&#039; conclusions:** 
There is insufficient evidence to conclude that selenium, DHA or EPA prevent postnatal depression. There is currently no evidence to recommend any other dietary supplement for prevention of postnatal depression.
AN  - CD009104
AU  - Miller,
AU  - B.
AU  - J.
AU  - Murray,
AU  - L.
AU  - Beckmann,
AU  - M.
AU  - M.
AU  - Kent,
AU  - T.
AU  - Macfarlane,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009104.pub2
KW  - Dietary Supplements
KW  - Depression, Postpartum [prevention &amp; control]
KW  - Docosahexaenoic Acids [administration &amp; dosage]
KW  - Eicosapentaenoic Acid [administration &amp; dosage]
KW  - Patient Dropouts [statistics &amp; numerical data]
KW  - Prenatal Care
KW  - Randomized Controlled Trials as Topic
KW  - Selenium [administration &amp; dosage]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Pregnancy[checkword]
KW  - Preg
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Dietary supplements for preventing postnatal depression
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009104.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009104.pub2/asset/CD009104.pdf?v=1&amp;t=iw7j9pr7&amp;s=67ff487dcfc340484278d416296d5d510a48dedc
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Interventions to prevent smoking uptake or encourage cessation among young persons might help prevent tobacco-related illness. PURPOSE: To review the evidence for the efficacy and harms of primary care-relevant interventions that aim to reduce tobacco use among children and adolescents. 

**DATA SOURCES:  **
Three systematic reviews that collectively covered the relevant literature; MEDLINE, PsycINFO, the Cochrane Central Register of Controlled Trials, and the Database of Abstracts of Reviews of Effects through 14 September 2012; and manual searches of reference lists and gray literature. 

**STUDY SELECTION:  **
Two investigators independently reviewed 2453 abstracts and 111 full-text articles. English-language trials of behavior-based or medication interventions that were relevant to primary care and reported tobacco use, health outcomes, or harms were included. 

DATA EXTRACTION: 
One investigator abstracted data from good- and fair-quality trials into an evidence table, and a second checked these data. 

**DATA SYNTHESIS: **
 19 trials (4 good-quality and 15 fair-quality) that were designed to prevent tobacco use initiation or promote cessation (or both) and reported self-reported smoking status or harms were included. Pooled analyses from a random-effects meta-analysis suggested a 19% relative reduction (risk ratio, 0.81 [95% CI, 0.70 to 0.93]; absolute risk difference, -0.02 [CI, -0.03 to 0.00]) in smoking initiation among participants in behavior-based prevention interventions compared with control participants. Neither behavior-based nor bupropion cessation interventions improved cessation rates. Findings about the harms related to bupropion use were mixed. 

**LIMITATIONS:  **
No studies reported health outcomes. Interventions and measures were heterogeneous. Most trials examined only cigarette smoking. The body of evidence was largely published 5 to 15 years ago. CONCLUSION: Primary care-relevant interventions may prevent smoking initiation over 12 months in children and adolescents.
AD  - Patnode,Carrie D. Kaiser Permanente Center for Health Research, 3800 North Interstate Avenue, Portland, OR 97227, USA.
AN  - 23229625
AU  - Patnode,
AU  - C.
AU  - D.
AU  - O&#039;
AU  - Connor,
AU  - E.
AU  - Whitlock,
AU  - E.
AU  - P.
AU  - Perdue,
AU  - L.
AU  - A.
AU  - Soh,
AU  - C.
AU  - Hollis,
AU  - J.
DA  - Feb 19
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.7326/0003-4819-158-4-201302190-00580
DP  - Ovid Technologies
J2  - Ann Intern Med
KW  - Adolescent Adolescent Behavior Bupropion/tu [Therapeutic Use] Child Counseling Humans *Primary Health Care Smoking/ep [Epidemiology] *Smoking/pc [Prevention &amp; Control] *Smoking Cessation 01ZG3TPX31 (Bupropion)
L1  - internal-pdf://3936543783/Patnode-2013-Primary care-relevant interventio.pdf
LA  - English
M3  - Research Support, U.S. Gov&#039;t, P.H.S. Review
N1  - Patnode, Carrie D O&#039;Connor, Elizabeth Whitlock, Evelyn P Perdue, Leslie A Soh, Clara Hollis, Jack HHS-290-2007-10057-I (United States PHS HHS)
PY  - 2013
SP  - 253-60
T2  - Annals of Internal Medicine
TI  - Primary care-relevant interventions for tobacco use prevention and cessation in children and adolescents: a systematic evidence review for the U.S. Preventive Services Task Force
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23229625
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23229625&amp;id=doi:10.7326%2F0003-4819-158-4-201302190-00580&amp;issn=0003-4819&amp;isbn=&amp;volume=158&amp;issue=4&amp;spage=253&amp;pages=253-60&amp;date=2013&amp;title=Annals+of+Internal+Medicine&amp;atitle=Primary+care-relevant+interventions+for+tobacco+use+prevention+and+cessation+in+children+and+adolescents%3A+a+systematic+evidence+review+for+the+U.S.+Preventive+Services+Task+Force.&amp;aulast=Patnode&amp;pid=%3Cauthor%3EPatnode+CD%3C%2Fauthor%3E%3CAN%3E23229625%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://annals.org/data/Journals/AIM/926387/0000605-201302190-00005.pdf
UR  - http://annals.org/data/journals/aim/926387/0000605-201302190-00005.pdf
VL  - 158
ER  -
TY  - JOUR
AB  - Throughout the trajectory of the cancer experience, children and adolescents will likely face pain and anxiety in a variety of circumstances. 
Integrative therapies may be used either alone or as an adjunct to standard analgesics. 

Children are often very receptive to integrative therapies such as music, art, guided imagery, massage, therapeutic play, distraction, and other modalities. 
The effect of integrative modalities on pain and anxiety in children with cancer has not been systematically examined across the entire cancer experience.

An in-depth search of PubMed, CINAHL, MedLine, PsychInfo, and Web of Science, integrative medicine journals, and the reference lists of review articles using the search terms pain, anxiety, pediatric, child*, oncology, cancer, neoplasm, complementary, integrative, nonconventional, and unconventional yielded 164 articles. 

Of these, 25 warranted full-text review. Cohen&#039;s d calculations show medium (d = 0.70) to extremely large (8.57) effect sizes indicating that integrative interventions may be very effective for pain and anxiety in children undergoing cancer treatment. 
Integrative modalities warrant further study with larger sample sizes to better determine their effectiveness in this population.
AD  - Univ Pittsburgh, Sch Nursing, Pittsburgh, PA 15261 USA. Thrane, S (reprint author), Univ Pittsburgh, Sch Nursing, 3500 Victoria St,Victoria Bldg, Pittsburgh, PA 15261 USA. sut11@pitt.edu
AN  - WOS:000328879700004
AU  - Thrane,
AU  - S,
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1043454213511538
J2  - J. Pediatr. Oncol. Nurs.
KW  - pediatric oncology integrative therapy pain anxiety ALTERNATIVE MEDICINE USE QUALITY-OF-LIFE PEDIATRIC CANCER COMPLEMENTARY DISTRESS HYPNOSIS SCALE DISTRACTION PREVALENCE MANAGEMENT Oncology Nursing
L1  - internal-pdf://0693371755/Thrane-2013-Effectiveness of Integrative Modal.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 278HL Times Cited: 1 Cited Reference Count: 44 Thrane, Susan NINR [T32NR011972] The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by an NINR T32 Training Grant (T32NR011972) in Cancer Survivorship. 1 SAGE PUBLICATIONS INC THOUSAND OAKS J PEDIATR ONCOL NURS
PY  - 2013
SP  - 320-332
T2  - Journal of Pediatric Oncology Nursing
TI  - Effectiveness of Integrative Modalities for Pain and Anxiety in Children and Adolescents With Cancer: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000328879700004http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109717/pdf/nihms577633.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109717/pdf/nihms577633.pdf
VL  - 30
ER  -
TY  - JOUR
AB  - Several reviews and meta-analyses have examined the effects of iodine on mental development. None focused on young children, so they were incomplete in summarizing the effects on this important age group. 

The current systematic review therefore examined the relationship between iodine and mental development of children 5 years old and under. A systematic review of articles using Medline (1980-November 2011) was carried out. We organized studies according to four designs: (1) randomized controlled trial with iodine supplementation of mothers; (2) non-randomized trial with iodine supplementation of mothers and/or infants; (3) prospective cohort study stratified by pregnant women&#039;s iodine status; (4) prospective cohort study stratified by newborn iodine status. 

Average effect sizes for these four designs were 0.68 (2 RCT studies), 0.46 (8 non-RCT studies), 0.52 (9 cohort stratified by mothers&#039; iodine status), and 0.54 (4 cohort stratified by infants&#039; iodine status). This translates into 6.9 to 10.2 IQ points lower in iodine deficient children compared with iodine replete children. Thus, regardless of study design, iodine deficiency had a substantial impact on mental development. 

Methodological concerns included weak study designs, the omission of important confounders, small sample sizes, the lack of cluster analyses, and the lack of separate analyses of verbal and non-verbal subtests. 

Quantifying more precisely the contribution of iodine deficiency to delayed mental development in young children requires more well-designed randomized controlled trials, including ones on the role of iodized salt.
AD  - Bougma,Karim. School of Dietetics and Human Nutrition, McGill University, 21111 Lakeshore Road, CINE Building, Sainte Anne-de-Bellevue, QC, H9X 3V9, Canada.
AN  - 23609774
AU  - Bougma,
AU  - K.
AU  - Aboud,
AU  - F.
AU  - E.
AU  - Harding,
AU  - K.
AU  - B.
AU  - Marquis,
AU  - G.
AU  - S.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3390/nu5041384
DP  - Ovid Technologies
J2  - Nutrients
KW  - Age Factors *Brain/de [Drug Effects] Brain/gd [Growth &amp; Development] *Child Behavior/de [Drug Effects] *Child Development/de [Drug Effects] Child, Preschool *Diet/ae [Adverse Effects] *Dietary Supplements Female Humans Infant Infant, Newborn Intelligenc
L1  - internal-pdf://4126655463/Bougma-2013-Iodine and mental development of c.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Bougma, Karim Aboud, Frances E Harding, Kimberly B Marquis, Grace S
PY  - 2013
SP  - 1384-416
T2  - Nutrients
TI  - Iodine and mental development of children 5 years old and under: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23609774 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23609774&amp;id=doi:10.3390%2Fnu5041384&amp;issn=2072-6643&amp;isbn=&amp;volume=5&amp;issue=4&amp;spage=1384&amp;pages=1384-416&amp;date=2013&amp;title=Nutrients&amp;atitle=Iodine+and+mental+development+of+children+5+years+old+and+under%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Bougma&amp;pid=%3Cauthor%3EBougma+K%3C%2Fauthor%3E%3CAN%3E23609774%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.mdpi.com/2072-6643/5/4/1384/pdf
UR  - http://www.mdpi.com/2072-6643/5/4/1384/pdf
VL  - 5
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To systematically review the efficacy and safety of oral Fe therapy in pre-school children (1-5 years) with non-anaemic Fe deficiency, determined by children&#039;s developmental and haematological status and the incidence of reported side-effects. DESIGN: A random-effects model was used to show mean differences with 95% confidence intervals of developmental and haematological scores between Fe-treated and non-treated groups. 

**SETTING:** 
MEDLINE, EMBASE, Cochrane library and bibliographies of identified articles were searched up to September 2011. Randomized and observational studies were assessed by two reviewers independently. Quality of the trials was assessed on the basis of concealment of allocation, method of randomization, masking of outcome assessment and completeness of follow-up. 

**SUBJECTS:**
From the titles of 743 articles, full text review was completed on forty-six and two randomized trials of acceptable quality met the inclusion criteria. The two trials included a total of sixty-nine children. 

**RESULTS: **
One study showed a statistically significant difference in the post-treatment Mental Developmental Index score among children who received oral Fe therapy v. no therapy (mean difference56?3, 95% CI 1?5, 11?0, P value not provided). Both studies showed significant improvement in serum ferritin level (mg/l: mean difference551? 1, 95% CI 33?6, 68?6, P,0?01 and mean difference517?1, 95% CI 7?5, 26?6, P value not provided, respectively) in children who received Fe therapy. 

**CONCLUSIONS:** 
Evidence is insufficient to recommend oral Fe therapy to children with non-anaemic Fe deficiency. There is urgent need of conducting adequately powered, randomized trials examining the efficacy of oral Fe therapy in pre-school children with non-anaemic Fe deficiency.
AD  - Abdullah,Kawsari. Division of Pediatric Medicine and the Pediatric Outcomes Research Team (PORT), Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada, M5G 1X8.
AN  - 22894941
AU  - Abdullah,
AU  - K.
AU  - Kendzerska,
AU  - T.
AU  - Shah,
AU  - P.
AU  - Uleryk,
AU  - E.
AU  - Parkin,
AU  - P.
AU  - C.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1017/s1368980012003709
DP  - Ovid Technologies
J2  - Public Health Nutr
KW  - *Anemia, Iron-Deficiency/bl [Blood] *Anemia, Iron-Deficiency/dt [Drug Therapy] Child, Preschool Humans Infant *Iron, Dietary/ad [Administration &amp; Dosage] Observational Study as Topic Randomized Controlled Trials as Topic Treatment Outcome 0 (Iron, Dieta
L1  - internal-pdf://2671240346/Abdullah-2013-Efficacy of oral iron therapy in.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Abdullah, Kawsari Kendzerska, Tetyana Shah, Prakesh Uleryk, Elizabeth Parkin, Patricia C (Canada Canadian Institutes of Health Research)
PY  - 2013
SP  - 1497-506
T2  - Public Health Nutrition
TI  - Efficacy of oral iron therapy in improving the developmental outcome of pre-school children with non-anaemic iron deficiency: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22894941
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22894941&amp;id=doi:10.1017%2FS1368980012003709&amp;issn=1368-9800&amp;isbn=&amp;volume=16&amp;issue=8&amp;spage=1497&amp;pages=1497-506&amp;date=2013&amp;title=Public+Health+Nutrition&amp;atitle=Efficacy+of+oral+iron+therapy+in+improving+the+developmental+outcome+of+pre-school+children+with+non-anaemic+iron+deficiency%3A+a+systematic+review.&amp;aulast=Abdullah&amp;pid=%3Cauthor%3EAbdullah+K%3C%2Fauthor%3E%3CAN%3E22894941%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://journals.cambridge.org/download.php?file=%2FPHN%2FPHN16_08%2FS1368980012003709a.pdf&amp;code=a982aec414f14ba06dc05fe2f918880a
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/E6446C0CE07CBF35286DD160C2250EE2/S1368980012003709a.pdf/div-class-title-efficacy-of-oral-iron-therapy-in-improving-the-developmental-outcome-of-pre-school-children-with-non-anaemic-iron-deficiency-a-systematic-review-div.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - **Background:**
In 2004, the U.S. Preventive Services Task Force determined that evidence was insufficient to recommend behavioral interventions and counseling to prevent child abuse and neglect. 

**Purpose:**
To review new evidence on the effectiveness of behavioral interventions and counseling in health care settings for reducing child abuse and neglect and related health outcomes, as well as adverse effects of interventions. 

**Data Sources: **
MEDLINE and PsycINFO (January 2002 to June 2012), Cochrane Central Register of Controlled Trials and Cochrane Database of Systematic Reviews (through the second quarter of 2012), Scopus, and reference lists. 

**Study Selection:** 
English-language trials of the effectiveness of behavioral interventions and counseling and studies of any design about adverse effects. Data Extraction: Investigators extracted data about study populations, designs, and outcomes and rated study quality using established criteria. 

**Data Synthesis: **
Eleven fair-quality randomized trials of interventions and no studies of adverse effects met inclusion criteria. A trial of risk assessment and interventions for abuse and neglect in pediatric clinics for families with children aged 5 years or younger indicated reduced physical assault, Child Protective Services (CPS) reports, nonadherence to medical care, and immunization delay among screened children. Ten trials of early childhood home visitation reported reduced CPS reports, emergency department visits, hospitalizations, and self-reports of abuse and improved adherence to immunizations and well-child care, although results were inconsistent. 

**Limitation:** 
Trials were limited by heterogeneity, low adherence, high loss to follow-up, and lack of standardized measures. 

**Conclusion:** Risk assessment and behavioral interventions in pediatric clinics reduced abuse and neglect outcomes for young children. Early childhood home visitation also reduced abuse and neglect, but results were inconsistent. Additional research on interventions to prevent child abuse and neglect is needed. 

Primary Funding Source: Agency for Healthcare Research and Quality. Ann Intern Med. 2013;158:179-190.
AD  - [Nelson, Heidi D.] Oregon Hlth &amp; Sci Univ, Pacific NW Evidence Based Practice Ctr, Portland, OR 97239 USA. Providence Hlth &amp; Serv, Providence Canc Ctr, Portland, OR USA. Nelson, HD (reprint author), Oregon Hlth &amp; Sci Univ, Pacific NW Evidence Based Practice Ctr, Mail Code BICC,3181 SW Sam Jackson Pk Rd, Portland, OR 97239 USA. nelsonh@ohsu.edu
AN  - WOS:000314757900005
AU  - Selph,
AU  - S.
AU  - S.
AU  - Bougatsos,
AU  - C.
AU  - Blazina,
AU  - I.
AU  - Nelson,
AU  - H.
AU  - D.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.7326/0003-4819-158-3-201302050-00590
J2  - Ann. Intern. Med.
KW  - RANDOMIZED-CONTROLLED-TRIAL INTIMATE PARTNER VIOLENCE PEDIATRIC PRIMARY-CARE NURSE HOME VISITATION TRAUMATIC BRAIN-INJURY DOMESTIC VIOLENCE VISITING PROGRAM NATIONAL-SURVEY PREGNANCY OUTCOMES SAFE ENVIRONMENT Medicine, General &amp; Internal
L1  - internal-pdf://1940270176/Selph-2013-Behavioral Interventions and Counse.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 087JP Times Cited: 10 Cited Reference Count: 69 Selph, Shelley S. Bougatsos, Christina Blazina, Ian Nelson, Heidi D. AHRQ [HHSA-290-2007-10057-I-EPC3] By AHRQ under contract HHSA-290-2007-10057-I-EPC3, task order 3. 10 AMER COLL PHYSICIANS PHILADELPHIA ANN INTERN MED
PY  - 2013
SP  - 179-+
T2  - Annals of Internal Medicine
TI  - Behavioral Interventions and Counseling to Prevent Child Abuse and Neglect: A Systematic Review to Update the U.S. Preventive Services Task Force Recommendation
UR  - &lt;Go to ISI&gt;://WOS:000314757900005http://annals.org/data/Journals/AIM/926316/0000605-201302050-00007.pdf
UR  - http://annals.org/data/journals/aim/926316/0000605-201302050-00007.pdf
VL  - 158
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To synthesise existing knowledge of the efficacy and safety of long-acting versus short-acting methylphenidate for paediatric attention deficit hyperactivity disorder (ADHD). 

**DESIGN: **
Systematic review and meta-analysis. 

**DATA SOURCES: **
Electronic literature search of CENTRAL, MEDLINE, PreMEDLINE, CINAHL, EMBASE, PsychINFO, Scopus and Web of Science for articles published in the English language between 1950 and 2012. Reference lists of included studies were checked for additional studies. 

**STUDY SELECTION: **
Randomised controlled trials of paediatric ADHD patients (&lt;18 years), comparing a long-acting methylphenidate form to a short-acting methylphenidate form. 

**DATA EXTRACTION: **
Two authors independently selected trials, extracted data and assessed risk of bias. Continuous outcomes were compared using standardised mean differences (SMDs) between treatment groups. Adverse events were compared using risk differences between treatment groups. Heterogeneity was explored by subgroup analysis based on the type of long-acting formulation used. 

**RESULTS: **
Thirteen RCTs were included; data from 882 participants contributed to the analysis. Meta-analysis of three studies which used parent ratings to report on hyperactivity/impulsivity had an SMD of -0.30 (95% CI -0.51 to -0.08) favouring the long-acting forms. In contrast, three studies used teacher ratings to report on hyperactivity and had an SMD of 0.29 (95% CI 0.05 to 0.52) favouring the short-acting methylphenidate. In addition, subgroup analysis of three studies which used parent ratings to report on inattention/overactivity indicate that the osmotic release oral system generation long-acting formulation was favoured with an SMD of -0.35 (95% CI -0.52 to -0.17), while the second generation showed less efficacy than the short-acting formulation with an SMD of 0.42 (95% CI 0.17 to 0.68). The long-acting formulations presented with slightly more total reported adverse events (n=578) as compared with the short-acting formulation (n=566). 

**CONCLUSIONS: **
The findings from this systematic review indicate that the long-acting forms have a modest effect on the severity of inattention/overactivity and hyperactivity/impulsivity according to parent reports, whereas the short-acting methylphenidate was preferred according to teacher reports for hyperactivity.
AD  - Punja,Salima. Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
AN  - 23503579
AU  - Punja,
AU  - S.
AU  - Zorzela,
AU  - L.
AU  - Hartling.
AU  - L.
AU  - Urichuk,
AU  - L.
AU  - Vohra,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1136/bmjopen-2012-002312
DP  - Ovid Technologies
J2  - BMJ Open
LA  - English
N1  - Punja, Salima Zorzela, Liliane Hartling, Lisa Urichuk, Liana Vohra, Sunita Using Smart Source Parsing e002312
PY  - 2013
T2  - BMJ Open
TI  - Long-acting versus short-acting methylphenidate for paediatric ADHD: a systematic review and meta-analysis of comparative efficacy
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=23503579 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23503579&amp;id=doi:10.1136%2Fbmjopen-2012-002312&amp;issn=2044-6055&amp;isbn=&amp;volume=3&amp;issue=3&amp;spage=&amp;pages=&amp;date=2013&amp;title=BMJ+Open&amp;atitle=Long-acting+versus+short-acting+methylphenidate+for+paediatric+ADHD%3A+a+systematic+review+and+meta-analysis+of+comparative+efficacy.&amp;aulast=Punja&amp;pid=%3Cauthor%3EPunja+S%3C%2Fauthor%3E%3CAN%3E23503579%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://bmjopen.bmj.com/content/3/3/e002312.full.pdf
VL  - 3
ER  -
TY  - JOUR
AB  - &lsquo;Scared Straight&rsquo; and other programs involve organized visits to prison by juvenile delinquents or children at risk for criminal behavior. Programs are designed to deter participants from future offending through first hand observation of prison life and interaction with adult inmates. 

**OBJECTIVES** 
To assess the effects of programs comprising organized visits to prisons by juvenile delinquents (officially adjudicated or convicted by a juvenile court) or pre-delinquents (children in trouble but not officially adjudicated as delinquents), aimed at deterring them from criminal activity. 

**SEARCH STRATEGY** 
Searches by the first author in identifying randomized field trials 1945-1993 relevant to criminology were augmented by structured searches of 29 electronic databases, including the Campbell SPECTR database of trials (through 2003) and the Cochrane CCTR (through 2011). Experts in the field were consulted and relevant citations were followed up. 

**SELECTION CRITERIA** 
Studies that tested the effects of any program involving the organized visits of juvenile delinquents or children at-risk for delinquency to penal institutions were included. Studies that included overlapping samples of juvenile and young adults (e.g. ages 14-20) were also included. We only considered studies that randomly or quasi-randomly (i.e. alternation) assigned participants to conditions. Each study had to have a no-treatment control condition with at least one outcome measure of &ldquo;post-visit&rdquo; criminal behavior. 

**DATA COLLECTION AND ANALYSIS** 
We report narratively on the nine eligible trials. We conducted one meta-analysis of post-intervention offending rates using official data. Information from other sources (e.g. self-report) was either missing from some studies or critical information was omitted (e.g. standard deviations). We examined the immediate post-treatment effects (i.e. &lsquo;first-effects&rsquo;) by computing Odds Ratios (OR) for data on proportions of each group re-offending, and assumed both fixed and random effects models in our analyses. 

**RESULTS**
The analyses show the intervention to be more harmful than doing nothing. The program effect, whether assuming a fixed or random effects model, was nearly identical and negative in direction, regardless of the meta-analytic strategy. 

**AUTHOR&rsquo;S CONCLUSIONS**
We conclude that programs like &lsquo;Scared Straight&rsquo; are likely to have a harmful effect and increase delinquency relative to doing nothing at all to the same youths. Given these results, we cannot recommend this program as a crime prevention strategy. Agencies that permit such programs, however, must rigorously evaluate them not only to ensure that they are doing what they purport to do (prevent crime) &ndash; but at the very least they do not cause more harm than good to the very citizens they pledge to protect.
AU  - Petrosino,
AU  - A.
AU  - Buehler,
AU  - J.
AU  - Turpin,
AU  - C.
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2013.5
KW  - Programme evaluation
KW  - Prisons
KW  - Juvenile delinquency
KW  - Awareness-raising activities
KW  - Adolescents
PY  - 2013
T2  - Campbell Systematic Reviews
TI  - Scared Straight and Other Juvenile Awareness Programs for Preventing Juvenile Delinquency: A Systematic Review
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
The purpose of this article was to systematically review the literature on stimulant and atomoxetine combination therapy, in particular: 1) Characteristics of patients with attention-deficit/hyperactivity disorder (ADHD) given combination therapy, 2) treatment strategies used, 3) efficacy and effectiveness, and 4) safety and tolerability. 

**METHODS: **
Literature databases (MEDLINE(), EMBASE, Cochrane Central Register of Controlled Trials, Science Citation Index Expanded, and SciVerse Scopus) were systematically searched using prespecified criteria. Publications describing stimulant and atomoxetine combination therapy in patients with ADHD or healthy volunteers were selected for review. Exclusion criteria were comorbid psychosis, bipolar disorder, epilepsy, or other psychiatric/neurologic diseases that could confound ADHD symptom assessment, or other concomitant medication(s) to treat ADHD symptoms. 

**RESULTS: **
Of the 16 publications included for review, 14 reported findings from 3 prospective studies (4 publications), 7 retrospective studies, and 3 narrative reviews/medication algorithms of patients with ADHD. The other two publications reported findings from two prospective studies of healthy volunteers. The main reason for prescribing combination therapy was inadequate response to previous treatment. In the studies of patients with ADHD, if reported, 1) most patients were children/adolescents and male, and had a combined ADHD subtype; 2) methylphenidate was most often used in combination with atomoxetine for treatment augmentation or switch; 3) ADHD symptom control was improved in some, but not all, patients; and 4) there were no serious adverse events. 

**CONCLUSIONS: **
Published evidence of the off-label use of stimulant and atomoxetine combination therapy is limited because of the small number of publications, heterogeneous study designs (there was only one prospective, randomized controlled trial), small sample sizes, and geographic bias. Existing evidence suggests, but does not confirm, that this drug combination may benefit some, but not all, patients who have tried several ADHD medications without success.
AD  - Treuer,Tamas. Neuroscience Research, Eli Lilly and Company, Budapest, Hungary. treuert@lilly.com
AN  - 23560600
AU  - Treuer,
AU  - T.
AU  - Gau,
AU  - S.
AU  - S.
AU  - Mendez,
AU  - L.
AU  - Montgomery,
AU  - W.
AU  - Monk,
AU  - J.
AU  - A.
AU  - Altin,
AU  - M.
AU  - Wu,
AU  - S.
AU  - Lin,
AU  - C.
AU  - C.
AU  - Duenas,
AU  - H.
AU  - J.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1089/cap.2012.0093
DP  - Ovid Technologies
J2  - J Child Adolesc Psychopharmacol
KW  - Adrenergic Uptake Inhibitors/ad [Administration &amp; Dosage] Adrenergic Uptake Inhibitors/ae [Adverse Effects] *Adrenergic Uptake Inhibitors/tu [Therapeutic Use] *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] Central Nervous System Stimul
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Treuer, Tamas Gau, Susan Shur-Fen Mendez, Luis Montgomery, William Monk, Julie A Altin, Murat Wu, Shenghu Lin, Chaucer C H Duenas, Hector J
PY  - 2013
SP  - 179-93
T2  - Journal of Child &amp; Adolescent Psychopharmacology
TI  - A systematic review of combination therapy with stimulants and atomoxetine for attention-deficit/hyperactivity disorder, including patient characteristics, treatment strategies, effectiveness, and tolerability
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23560600
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23560600&amp;id=doi:10.1089%2Fcap.2012.0093&amp;issn=1044-5463&amp;isbn=&amp;volume=23&amp;issue=3&amp;spage=179&amp;pages=179-93&amp;date=2013&amp;title=Journal+of+Child+%26+Adolescent+Psychopharmacology&amp;atitle=A+systematic+review+of+combination+therapy+with+stimulants+and+atomoxetine+for+attention-deficit%2Fhyperactivity+disorder%2C+including+patient+characteristics%2C+treatment+strategies%2C+effectiveness%2C+and+tolerability.&amp;aulast=Treuer&amp;pid=%3Cauthor%3ETreuer+T%3C%2Fauthor%3E%3CAN%3E23560600%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://online.liebertpub.com/doi/pdfplus/10.1089/cap.2012.0093
VL  - 23
ER  -
TY  - JOUR
AB  - **Background:** 
A meta-analysis of 21 studies suggests the mean prevalence rate for depression across the antenatal period is 10.7%, ranging from 7.4% in the first trimester to a high of 12.8% in the second trimester. Due to maternal treatment preferences and potential concerns about fetal and infant health outcomes, diverse non-pharmacological treatment options are needed.

**Objectives:** 
To assess the effect of interventions other than pharmacological, psychosocial, or psychological interventions compared with usual antepartum care in the treatment of antenatal depression.

**Search methods:** 
We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (31 January 2013), scanned secondary references and contacted experts in the field to identify other published or unpublished trials.

**Selection criteria:**
All published and unpublished randomised controlled trials of acceptable quality evaluating non-pharmacological/psychosocial/psychological interventions to treat antenatal depression.

**Data collection and analysis:**
Both review authors participated in the evaluation of methodological quality and data extraction. Results are presented using risk ratio (RR) for categorical data and mean difference (MD) for continuous data.

**Main results:** 
Six trials were included involving 402 women from the United States, Switzerland, and Taiwan. For most comparisons a single trial contributed data and there were few statistically significant differences between control and intervention groups.In a trial with 38 women maternal massage compared with non-specific acupuncture (control group) did not significantly decrease the number of women with clinical depression or depressive symptomatology immediately post-treatment (risk ratio (RR) 0.80, 95% confidence interval (CI) 0.25 to 2.53; mean difference (MD) -2.30, 95% CI -6.51 to 1.91 respectively). In another trial with 88 women there was no difference in treatment response or depression remission rates in women receiving maternal massage compared with those receiving non-specific acupuncture (RR 1.33, 95% CI 0.82 to 2.18; RR 1.14, 95% CI 0.59 to 2.19 respectively).In a trial with 35 women acupuncture specifically treating symptoms of depression, compared with non-specific acupuncture, did not significantly decrease the number of women with clinical depression or depressive symptomatology immediately post-treatment (RR 0.47, 95% CI 0.11 to 2.13; MD -3.00, 95% CI -8.10 to 2.10). However, women who received depression-specific acupuncture were more likely to respond to treatment compared with those receiving non-specific acupuncture (RR 1.68, 95% CI 1.06 to 2.66).In a trial with 149 women, maternal massage by a woman&#039;s significant other, compared with standard care, significantly decreased the number of women with depressive symptomatology immediately post-treatment (MD -6.70, 95% CI -9.77 to -3.63). Further, women receiving bright light therapy had a significantly greater change in their mean depression scores over the five weeks of treatment than those receiving a dim light placebo (one trial, n = 27; MD -4.80, 95% CI -8.39 to -1.21). However, they were not more likely to have a treatment response or experience a higher remission rate (RR 1.79, 95% CI 0.90 to 3.56; RR 1.89, 95% CI 0.81 to 4.42).Lastly, two trials examined the treatment effect of omega-3 oils. Women receiving omega-3 had a significantly lower mean depression score following eight weeks of treatment than those receiving a placebo (one trial, n = 33; MD -4.70, 95% CI -7.82 to -1.58). Conversely, in a smaller trial (21 women) there was no significant difference in the change in mean depression scores for women receiving omega-3 and those receiving a placebo (MD 0.36, 95% CI -0.17 to 0.89), and women who received omega-3 were no more likely to respond to treatment (RR 2.26, 95% CI 0.78 to 6.49) or have higher remission rates (RR 2.12, 95% CI 0.51 to 8.84). Women in the placebo group were just as likely to report a side effect as those in the omega-3 group (RR 1.12, 95% CI 0.56 to 2.27).

**Authors&#039; conclusions:** 
The evidence is inconc sive to allow us to make any recommendations for depression-specific acupuncture, maternal massage, bright light therapy, and omega-3 fatty acids for the treatment of antenatal depression. The included trials were too small with non-generalisable samples, to make any recommendations.
AN  - CD006795
AU  - Dennis,
AU  - C.
AU  - L.
AU  - Dowswell,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd006795.pub3
KW  - Acupuncture Therapy
KW  - Massage
KW  - Phototherapy
KW  - Depression [therapy]
KW  - Fatty Acids, Omega-3 [therapeutic use]
KW  - Pregnancy Complications [psychology] [therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Pregnancy[checkword]
KW  - Preg
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions (other than pharmacological, psychosocial or psychological) for treating antenatal depression
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006795.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006795.pub3/asset/CD006795.pdf?v=1&amp;t=iw7jteag&amp;s=a3760cf90d3d762db756896fc3cbc07f4137c987
ER  -
TY  - JOUR
AB  - **Background: **
The development of effective treatments for use by non-specialists is listed among the top research priorities for improving the lives of people with mental illness worldwide. The purpose of this review is to appraise which interventions for children with intellectual disabilities or lower-functioning autism spectrum disorders delivered by non-specialist care providers in community settings produce benefits when compared to either a no-treatment control group or treatment-as-usual comparator. 

**Methods and Findings: **
We systematically searched electronic databases through 24 June 2013 to locate prospective controlled studies of psychosocial interventions delivered by non-specialist providers to children with intellectual disabilities or lower-functioning autism spectrum disorders. We screened 234 full papers, of which 34 articles describing 29 studies involving 1,305 participants were included. A majority of the studies included children exclusively with a diagnosis of lower-functioning autism spectrum disorders (15 of 29, 52%). Fifteen of twenty-nine studies (52%) were randomized controlled trials and just under half of all effect sizes (29 of 59, 49%) were greater than 0.50, of which 18 (62%) were statistically significant. For behavior analytic interventions, the best outcomes were shown for development and daily skills; cognitive rehabilitation, training, and support interventions were found to be most effective for improving developmental outcomes, and parent training interventions to be most effective for improving developmental, behavioral, and family outcomes. We also conducted additional subgroup analyses using harvest plots. Limitations include the studies&#039; potential for performance bias and that few were conducted in lower-and middle-income countries. 

**Conclusions:**
 The findings of this review support the delivery of psychosocial interventions by non-specialist providers to children who have intellectual disabilities or lower-functioning autism spectrum disorders. Given the scarcity of specialists in many low-resource settings, including many lower-and middle-income countries, these findings may provide guidance for scale-up efforts for improving outcomes for children with developmental disorders or lower-functioning autism spectrum disorders. Protocol 

**Registration: **
PROSPERO CRD42012002641
AD  - [Reichow, Brian] Yale Univ, Sch Med, Yale Child Study Ctr, New Haven, CT 06520 USA. [Reichow, Brian] Univ Connecticut, Ctr Hlth, Farmington, CT USA. [Servili, Chiara; Yasamy, M. Taghi; Saxena, Shekhar] World Hlth Org, Geneva, Switzerland. [Barbui, Corrado] Univ Verona, WHO Collaborating Ctr Res &amp; Training Mental Hlth, Sect Psychiat, Dept Publ Hlth &amp; Community Med, I-37100 Verona, Italy. Reichow, B (reprint author), Yale Univ, Sch Med, Yale Child Study Ctr, New Haven, CT 06520 USA. reichow@uchc.edu
AN  - WOS:000330534300011
AU  - Reichow,
AU  - B.
AU  - Servili,
AU  - C.
AU  - Yasamy,
AU  - M.
AU  - T.
AU  - Barbui,
AU  - C.
AU  - Saxena,
AU  - S.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1371/journal.pmed.1001572
J2  - PLos Med.
KW  - RANDOMIZED CONTROLLED-TRIAL INTENSIVE BEHAVIORAL TREATMENT MIDDLE-INCOME COUNTRIES GLOBAL MENTAL-HEALTH EARLY LITERACY PROGRAM DEVELOPMENTAL-DISABILITIES YOUNG-CHILDREN DOWN-SYNDROME SCREENING QUESTIONNAIRE FAMILY INTERVENTION Medicine, General &amp; Intern
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 301LR Times Cited: 3 Cited Reference Count: 175 Reichow, Brian Servili, Chiara Yasamy, M. Taghi Barbui, Corrado Saxena, Shekhar Autism Speaks WHO supported this review through a fund from Autism Speaks (www.autismspeaks.org). The authors alone are responsible for the views expressed in this publication and these views do not necessarily represent the decisions, policy, or views of the universities by which the authors are associated, the World Health Organization, or any of the funders. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. 3 PUBLIC LIBRARY SCIENCE SAN FRANCISCO PLOS MED
PY  - 2013
SP  - 27
T2  - Plos Medicine
TI  - Non-Specialist Psychosocial Interventions for Children and Adolescents with Intellectual Disability or Lower-Functioning Autism Spectrum Disorders: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000330534300011http://www.plosmedicine.org/article/fetchObject.action?uri=info:doi/10.1371/journal.pmed.1001572&amp;representation=PDF
VL  - 10
ER  -
TY  - JOUR
AB  - BACKGROUND AND OBJECTIVES: 
Iron deficiency (ID) is the most common cause of anemia worldwide. The prevalence is highest among preschool-aged children. Iron is widely administered to children with or at risk for ID, but evidence of benefit among 2- to 5-year-old children has not been evaluated by systematic review. We summarize the evidence for the benefit and safety of daily iron supplementation with regard to hematologic, growth, and cognitive parameters in 2 to 5 year olds. 

METHODS: 
Electronic databases, regional databases, thesis repositories, gray literature, and references of studies and previous reviews were searched. We included randomized controlled trials that compared daily oral iron supplementation with control in 2 to 5 year olds. A random-effects meta-analysis was used to synthesize predefined outcomes reported by at least 2 studies. 

RESULTS: 
Of 9169 references, 15 studies met the inclusion criteria, none of which were at low risk of bias. Children receiving iron supplementation had a mean end point hemoglobin of 6.97 g/L (P &lt; .00001; I(2) = 82%) greater than controls, whereas mean end point ferritin was 11.64 micro g/L (P &lt; .0001; I(2) = 48%) greater. No trials reported the effects of iron supplementation on ID or iron deficiency anemia, and only one reported on anemia. Limited evidence suggested that iron supplementation produced a small improvement in cognitive development but had no effect on physical growth. 

CONCLUSIONS: 
In 2 to 5 year olds, daily iron supplementation increases hemoglobin and ferritin. There is a concerning lack of data on the effect of iron supplementation on clinically important outcomes including anemia, ID anemia, ID, and cognitive development. Additional interventional studies in this age group are needed.
AD  - Thompson,Jane. School of Medicine, Faculty of Health Sciences, University of Adelaide, South Australia, Australia.
AN  - 23478873
AU  - Thompson,
AU  - J.
AU  - Biggs,
AU  - B.
AU  - A.
AU  - Pasricha,
AU  - S.
AU  - R.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2012-2256
DP  - Ovid Technologies
J2  - Pediatrics
KW  - *Anemia, Iron-Deficiency/pc [Prevention &amp; Control] Biological Markers/bl [Blood] Child Development/de [Drug Effects] Child, Preschool Cognition/de [Drug Effects] *Dietary Supplements Drug Administration Schedule Ferritins/bl [Blood] Growth/de [Drug Effe
L1  - internal-pdf://1828387589/Thompson-2013-Effects of daily iron supplement.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Thompson, Jane Biggs, Beverley-Ann Pasricha, Sant-Rayn Comment in: Evid Based Med. 2014 Feb;19(1):21; PMID: 23975206
PY  - 2013
SP  - 739-53
T2  - Pediatrics
TI  - Effects of daily iron supplementation in 2- to 5-year-old children: systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23478873 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23478873&amp;id=doi:10.1542%2Fpeds.2012-2256&amp;issn=0031-4005&amp;isbn=&amp;volume=131&amp;issue=4&amp;spage=739&amp;pages=739-53&amp;date=2013&amp;title=Pediatrics&amp;atitle=Effects+of+daily+iron+supplementation+in+2-+to+5-year-old+children%3A+systematic+review+and+meta-analysis.&amp;aulast=Thompson&amp;pid=%3Cauthor%3EThompson+J%3C%2Fauthor%3E%3CAN%3E23478873%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://pediatrics.aappublications.org/content/131/4/739.full.pdf
UR  - http://pediatrics.aappublications.org/content/pediatrics/131/4/739.full.pdf
VL  - 131
ER  -
TY  - JOUR
AB  - **Purpose: **
Prompted by calls to implement evidence-based practices (EBPs) into residential care settings (RCS), this review addresses three questions: (1) Which EBPs have been tested with children and youth within the context of RCS? (2) What is the evidence for their effectiveness within such settings? (3) What implementation issues arise when transporting EBPs into RCS? 

**Methods: **
Evidence-based psychosocial interventions and respective outcome studies, published from 1990 to 2012, were identified through a multi-phase search process, involving the review of four major clearinghouse websites and relevant electronic databases. To be included, effectiveness had to have been previously established through a comparison group design regardless of the setting, and interventions tested subsequently with youth in RCS. All outcome studies were evaluated for quality and bias using a structured appraisal tool. 

**Results: **
Ten interventions matching a priori criteria were identified: Adolescent Community Reinforcement Approach, Aggression Replacement Training, Dialectical Behavioral Therapy, Ecologically-Based Family Therapy, Eye Movement and Desensitization Therapy, Functional Family Therapy, Multimodal Substance Abuse Prevention, Residential Student Assistance Program, Solution-Focused Brief Therapy, and Trauma Intervention Program for Adjudicated and At-Risk Youth. Interventions were tested in 13 studies, which were conducted in different types of RCS, using a variety of study methods. Outcomes were generally positive, establishing the relative effectiveness of the interventions with youth in RCS across a range of psychosocial outcomes. However, concerns about methodological bias and confounding factors remain. Most studies addressed implementation issues, reporting on treatment adaptations, training and supervision, treatment fidelity and implementation barriers. 

**Conclusion: **
The review unearthed a small but important body of knowledge that demonstrates that EBPs can be implemented in RCS with encouraging results. (C) 2013 Elsevier Ltd. All rights reserved.
AD  - [James, Sigrid; Alemi, Qais; Zepeda, Veronica] Loma Linda Univ, Dept Social Work &amp; Social Ecol, Loma Linda, CA 92350 USA. James, S (reprint author), Loma Linda Univ, Dept Social Work &amp; Social Ecol, Loma Linda, CA 92350 USA. ssjames@llu.edu
AN  - WOS:000316372600008
AU  - James,
AU  - S.
AU  - Alemi,
AU  - Q.
AU  - Zepeda,
AU  - V.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2013.01.007
J2  - Child. Youth Serv. Rev.
KW  - Evidence-based practice Residential care Group homes Residential treatment Systematic review Effectiveness ASSERTIVE CONTINUING CARE SUBSTANCE USE MENTAL-HEALTH ADOLESCENTS THERAPY BEHAVIOR OUTCOMES INSTITUTIONS DISORDERS CHILDREN Family Studies Social
L1  - internal-pdf://3886862455/James-2013-Effectiveness and implementation of.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 109ML Times Cited: 2 Cited Reference Count: 52 James, Sigrid Alemi, Qais Zepeda, Veronica 2 PERGAMON-ELSEVIER SCIENCE LTD OXFORD CHILD YOUTH SERV REV
PY  - 2013
SP  - 642-656
T2  - Children and Youth Services Review
TI  - Effectiveness and implementation of evidence-based practices in residential care settings
UR  - &lt;Go to ISI&gt;://WOS:000316372600008http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629969/pdf/nihms448567.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629969/pdf/nihms448567.pdf
VL  - 35
ER  -
TY  - JOUR
AB  - **Background **
To investigate the effects of booster sessions in cognitive behavioral therapy (CBT) for children and adolescents with mood or anxiety disorders, whereas controlling for youth demographics (e.g., gender, age), primary diagnosis, and intervention characteristics (e.g., treatment modality, number of sessions). 

**Methods **
Electronic databases were searched for CBT interventions for youth with mood and anxiety disorders. Fifty-three (k = 53) studies investigating 1,937 youth met criteria for inclusion. Booster sessions were examined using two case-controlled effect sizes: pre-post and pre-follow-up (6 months) effect sizes and employing weighted least squares (WLSs) regressions. 

**Results **
Meta-analyses found pre-post studies with booster sessions had a larger effect size r =.58 (k = 15; 95% CI = 0.52-0.65; P &lt;.01) than those without booster sessions r =.45 (k = 38; 95% CI = 0.41-0.49; P &lt;.001). In the WLS regression analyses, controlling for demographic factors, primary diagnosis, and intervention characteristics, studies with booster sessions showed larger pre-post effect sizes than those without booster sessions (B = 0.13, P &lt;.10). Similarly, pre-follow-up studies with booster sessions showed a larger effect size r =.64 (k = 10; 95% CI = 0.57-0.70; P &lt;.10) than those without booster sessions r =.48 (k = 20; 95% CI = 0.42-0.53; P &lt;.01). Also, in the WLS regression analyses, pre-follow-up studies showed larger effect sizes than those without booster sessions (B = 0.08, P &lt;.01) after accounting for all control variables. 

**Conclusions **
Result suggests that CBT interventions with booster sessions are more effective and the effect is more sustainable for youth managing mood or anxiety disorders than CBT interventions without booster sessions. 

&copy; 2013 Wiley Periodicals, Inc.
AD  - (Gearing, Schwalbe, Lee) Columbia University, 1255 Amsterdam Avenue, New York, NY 10027, United States (Hoagwood) Department of Child and Adolescent Psychiatry, New York University, School of Medicine, New York, NY, United States R.E. Gearing, Columbia University, 1255 Amsterdam Avenue, New York, NY 10027, United States. E-mail: rg2372@columbia.edu
AN  - 2013563705
AU  - Gearing,
AU  - R.
AU  - E.
AU  - Schwalbe,
AU  - C.
AU  - S.
AU  - J.
AU  - Lee,
AU  - R.
AU  - Hoagwood,
AU  - K.
AU  - E.
DA  - September
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/da.22118
DP  - Ovid Technologies
KW  - anxiety/anxiety disorders booster session CBT/cognitive behavior therapy child/adolescent empirical supported treatments mood disorders treatment adolescence anxiety disorder/th [Therapy] article behavior therapy cognitive therapy data base demography d
LA  - English
PY  - 2013
SP  - 800-808
T2  - Depression and Anxiety
TI  - The effectiveness of booster sessions in CBT treatment for child and adolescent mood and anxiety disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed11&amp;AN=2013563705 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1002%2Fda.22118&amp;issn=1091-4269&amp;isbn=&amp;volume=30&amp;issue=9&amp;spage=800&amp;pages=800-808&amp;date=2013&amp;title=Depression+and+Anxiety&amp;atitle=The+effectiveness+of+booster+sessions+in+CBT+treatment+for+child+and+adolescent+mood+and+anxiety+disorders&amp;aulast=Gearing&amp;pid=%3Cauthor%3EGearing+R.E.%3C%2Fauthor%3E%3CAN%3E2013563705%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1002/da.22118/asset/da22118.pdf?v=1&amp;t=ib7v8r4g&amp;s=635aff72b2b5292cf0113cd528d2ab25938eaa2e
UR  - http://onlinelibrary.wiley.com/doi/10.1002/da.22118/abstract
VL  - 30
ER  -
TY  - JOUR
AB  - **Background:** 
Epidemiological studies and meta-analyses of predictive studies have consistently demonstrated the importance of psychosocial and psychological variables as postpartum depression risk factors. While interventions based on these variables may be effective treatment strategies, theoretically they may also be used in pregnancy and the early postpartum period to prevent postpartum depression.

**Objectives:** 
Primary: to assess the effect of diverse psychosocial and psychological interventions compared with usual antepartum, intrapartum, or postpartum care to reduce the risk of developing postpartum depression. Secondary: to examine (1) the effectiveness of specific types of psychosocial and psychological interventions, (2) the effectiveness of professionally-based versus lay-based interventions, (3) the effectiveness of individually-based versus group-based interventions, (4) the effects of intervention onset and duration, and (5) whether interventions are more effective in women selected with specific risk factors.

**Search methods:** 
We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (30 November 2011), scanned secondary references and contacted experts in the field. We updated the search on 31 December 2012 and added the results to the awaiting classification section of the review for assessment at the next update.

**Selection criteria:**
All published and unpublished randomised controlled trials of acceptable quality comparing a psychosocial or psychological intervention with usual antenatal, intrapartum, or postpartum care.

**Data collection and analysis:**
Review authors and a research co-ordinator with Cochrane review experience participated in the evaluation of methodological quality and data extraction. Additional information was sought from several trial researchers. Results are presented using risk ratio (RR) for categorical data and mean difference (MD) for continuous data.

**Main results:** 
Twenty-eight trials, involving almost 17,000 women, contributed data to the review. Overall, women who received a psychosocial or psychological intervention were significantly less likely to develop postpartum depression compared with those receiving standard care (average RR 0.78, 95% confidence interval (CI) 0.66 to 0.93; 20 trials, 14,727 women). Several promising interventions include: (1) the provision of intensive, individualised postpartum home visits provided by public health nurses or midwives (RR 0.56, 95% CI 0.43 to 0.73; two trials, 1262 women); (2) lay (peer)-based telephone support (RR 0.54, 95% CI 0.38 to 0.77; one trial, 612 women); and (3) interpersonal psychotherapy (standardised mean difference -0.27, 95% CI -0.52 to -0.01; five trials, 366 women). Professional- and lay-based interventions were both effective in reducing the risk to develop depressive symptomatology. Individually-based interventions reduced depressive symptomatology at final assessment (RR 0.75, 95% CI 0.61 to 0.92; 14 trials, 12,914 women) as did multiple-contact interventions (RR 0.78, 95% CI 0.66 to 0.93; 16 trials, 11,850 women). Interventions that were initiated in the postpartum period also significantly reduced the risk to develop depressive symptomatology (RR 0.73, 95% CI 0.59 to 0.90; 12 trials, 12,786 women). Identifying mothers &#039;at-risk&#039; assisted the prevention of postpartum depression (RR 0.66, 95% CI 0.50 to 0.88; eight trials, 1853 women).

**Authors&#039; conclusions:**
Overall, psychosocial and psychological interventions significantly reduce the number of women who develop postpartum depression. Promising interventions include the provision of intensive, professionally-based postpartum home visits, telephone-based peer support, and interpersonal psychotherapy.
AN  - CD001134
AU  - Dennis,
AU  - C.
AU  - L.
AU  - Dowswell,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd001134.pub3
KW  - Depression, Postpartum [prevention &amp; control]
KW  - Family Health
KW  - House Calls
KW  - Peer Group
KW  - Psychotherapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Social Support
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Preg
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Psychosocial and psychological interventions for preventing postpartum depression
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001134.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD001134.pub3/asset/CD001134.pdf?v=1&amp;t=iw7kvdpz&amp;s=8d3d6329832488a1e6499c0d33af490ef7f451ef
ER  -
TY  - JOUR
AB  - Objectives: 
Given the high rates at which adolescents engage in violence, the strong link between adolescent and adult violence, and the financial and social costs of violence, the prevention of violent behavior is a national priority. 

Methods: 
The authors conducted a comprehensive review of evaluations utilizing quasi-experimental or experimental research designs to assess violence reduction. 

Results: 
Seventeen interventions were identified as producing a significant reduction in youth-perpetrated physical or sexual violence. The interventions were varied in terms of targeted age groups, content, strategies, and length of programming, and included programs focusing on individual, peer, school, family, and community factors. 

Conclusions:
Widespread use of effective interventions such as these, across settings and development, and implemented with fidelity, is likely to substantially reduce youth violence. Continued evaluation of violence prevention programming is also needed to increase the number of options available for replication and establish effects on diverse populations. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Fagan, Abigail A.: afagan@fsu.edu Fagan, Abigail A.: College of Criminology and Criminal Justice, Florida State University, Tallahassee, FL, US, 32306, afagan@fsu.edu Fagan, Abigail A.: College of Criminology and Criminal Justice, Florida State University, Tallahassee, FL, US Catalano, Richard F.: Social Development Research Group, School of Social Work, University of Washington, Seattle, WA, US
AN  - 2013-07839-002
AU  - Fagan,
AU  - A.
AU  - Catalano,
AU  - R.
AU  - F.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1049731512465899
DP  - Ovid Technologies
KW  - youth violence prevention, violent behavior *Prevention *Violence Health &amp; Mental Health Treatment &amp; Prevention [3300] Human
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2013
SP  - 141-156
T2  - Research on Social Work Practice
TI  - What works in youth violence prevention: A review of the literature
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-07839-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1049731512465899&amp;issn=1049-7315&amp;isbn=&amp;volume=23&amp;issue=2&amp;spage=141&amp;pages=141-156&amp;date=2013&amp;title=Research+on+Social+Work+Practice&amp;atitle=What+works+in+youth+violence+prevention%3A+A+review+of+the+literature.&amp;aulast=Fagan&amp;pid=%3Cauthor%3EFagan%2C+Abigail+A%3C%2Fauthor%3E%3CAN%3E2013-07839-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rsw.sagepub.com/content/23/2/141http://rsw.sagepub.com/content/23/2/141.full.pdf
VL  - 23
ER  -
TY  - JOUR
AB  - BACKGROUND:
Mental health-related stigma is widespread and has major adverse effects on the lives of people with mental health problems. Its two major components are discrimination (being treated unfairly) and prejudice (stigmatising attitudes). Anti-stigma initiatives often include mass media interventions, and such interventions can be expensive. It is important to know if mass media interventions are effective.

OBJECTIVES:
To assess the effects of mass media interventions on reducing stigma (discrimination and prejudice) related to mental ill health compared to inactive controls, and to make comparisons of effectiveness based on the nature of the intervention (e.g. number of mass media components), the content of the intervention (e.g. type of primary message), and the type of media (e.g. print, internet).

SEARCH METHODS:
We searched eleven databases: the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, Issue 7, 2011); MEDLINE (OvidSP),1966 to 15 August 2011; EMBASE (OvidSP),1947 to 15 August 2011; PsycINFO (OvidSP), 1806 to 15 August 2011; CINAHL (EBSCOhost) 1981 to 16 August 2011; ERIC (CSA), 1966 to 16 August 2011; Social Science Citation Index (ISI), 1956 to 16 August 2011; OpenSIGLE (http://www.opengrey.eu/), 1980 to 18 August 2012; Worldcat Dissertations and Theses (OCLC), 1978 to 18 August 2011; metaRegister of Controlled Trials (http://www.controlled-trials.com/mrct/mrct_about.asp), 1973 to 18 August 2011; and Ichushi (OCLC), 1903 to 11 November 2011. We checked references from articles and reviews, and citations from included studies. We also searched conference abstracts and websites, and contacted researchers.

SELECTION CRITERIA:
Randomised controlled trials (RCTs), cluster RCTs or interrupted time series studies of mass media interventions compared to inactive controls in members of the general public or any of its constituent groups (excluding studies in which all participants were people with mental health problems), with mental health as a subject of the intervention and discrimination or prejudice outcome measures.

DATA COLLECTION AND ANALYSIS:
Two authors independently extracted data and assessed the risk of bias of included studies. We contacted study authors for missing information. Information about adverse effects was collected from study reports. Primary outcomes were discrimination and prejudice, and secondary outcomes were knowledge, cost, reach, recall, and awareness of interventions, duration/sustainability of media effects, audience reactions to media content, and unforeseen adverse effects. We calculated standardised mean differences and odds ratios. We conducted a primarily narrative synthesis due to the heterogeneity of included studies. Subgroup analyses were undertaken to examine the effects of the nature, content and type of mass media intervention.

MAIN RESULTS:
We included 22 studies involving 4490 participants. All were randomised trials (3 were cluster RCTs), and 19 of the 22 studies had analysable outcome data. Seventeen of the studies had student populations. Most of the studies were at unclear or high risk of bias for all forms of bias except detection bias.Findings from the five trials with discrimination outcomes (n = 1196) were mixed, with effects showing a reduction, increase or consistent with no evidence of effect. The median standardised mean difference (SMD) for the three trials (n = 394) with continuous outcomes was -0.25, with SMDs ranging from -0.85 (95% confidence interval (CI) -1.39 to -0.31) to -0.17 (95% CI -0.53 to 0.20). Odds ratios (OR) for the two studies (n = 802) with dichotomous discrimination outcomes showed no evidence of effect: results were 1.30 (95% CI 0.53 to 3.19) and 1.19 (95% CI 0.85 to 1.65).The 19 trials (n = 3176) with prejudice outcomes had median SMDs favouring the intervention, at the three following time periods: -0.38 (immediate), -0.38 (1 week to 2 months) and -0.49 (6 to 9 months). SMDs for prejudice outcomes across all studies ranged from -2.94 (95% CI -3.52 to -2.37) to 2.40 (95% CI 0.62 to 4.18). The median SMDs indicate that mass media interventions may have a small to medium effect in decreasing prejudice, and are equivalent to reducing the level of prejudice from that associated with schizophrenia to that associated with major depression.The studies were very heterogeneous, statistically, in their populations, interventions and outcomes, and only two meta-analyses within two subgroups were warranted. Data on secondary outcomes were sparse. Cost data were provided on request for three studies (n = 416), were highly variable, and did not address cost-effectiveness. Two studies (n = 455) contained statements about adverse effects and neither reported finding any.

AUTHORS&#039; CONCLUSIONS:
Mass media interventions may reduce prejudice, but there is insufficient evidence to determine their effects on discrimination. Very little is known about costs, adverse effects or other outcomes. Our review found few studies in middle- and low-income countries, or with employers or health professionals as the target group, and none targeted at children or adolescents. The findings are limited by the quality of the evidence, which was low for the primary outcomes for discrimination and prejudice, low for adverse effects and very low for costs. More research is required to establish the effects of mass media interventions on discrimination, to better understand which types of mass media intervention work best, to provide evidence about cost-effectiveness, and to fill evidence gaps about types of mass media not covered in this review. Such research should use robust methods, report data more consistently with reporting guidelines and be less reliant on student populations.
AN  - CD009453
AU  - Clement,
AU  - S.
AU  - Lassman,
AU  - F.
AU  - Barley,
AU  - E.
AU  - Evans-Lacko,
AU  - S.
AU  - Williams,
AU  - P.
AU  - Yamaguchi,
AU  - S.
AU  - Slade,
AU  - M.
AU  - R&uuml;sch,
AU  - N.
AU  - Thornicroft,
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009453
KW  - Mass Media
KW  - Mental Disorders
KW  - Social Stigma
KW  - Depressive Disorder, Major
KW  - Mental Health
KW  - Prejudice [prevention &amp; control]
KW  - Randomized Controlled Trials as Topic
KW  - Schizophrenia
KW  - Social Discrimination [prevention &amp; control]
KW  - Humans[checkword]
KW  - Commun
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Mass media interventions for reducing mental health-related stigma
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009453.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009453.pub2/asset/CD009453.pdf?v=1&amp;t=iw7k0xxh&amp;s=198b4880c0485e55348828f793dab018113407b1
ER  -
TY  - JOUR
AB  - **Background:** 
Substance-specific mass media campaigns which address young people are widely used to prevent illicit drug use. They aim to reduce use and raise awareness of the problem.

**Objectives:** To assess the effectiveness of mass media campaigns in preventing or reducing the use of or intention to use illicit drugs amongst young people.

**Search methods:** 
We searched the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library 2013, Issue 1), including the Cochrane Drugs and Alcohol Group&#039;s Specialised Register; MEDLINE through PubMed (from 1966 to 29 January 2013); EMBASE (from 1974 to 30 January 2013) and ProQuest Dissertations &amp; Theses A&amp;I (from 1861 to 3 February 2013).

**Selection criteria:** 
Cluster-randomised controlled trials, prospective and retrospective cohort studies, interrupted time series and controlled before and after studies evaluating the effectiveness of mass media campaigns in influencing drug use, intention to use or the attitude of young people under the age of 26 towards illicit drugs.

**Data collection and analysis:** 
We used the standard methodological procedures of The Cochrane Collaboration.

**Main results:**
We included 23 studies involving 188,934 young people, conducted in the USA, Canada and Australia between 1991 and 2012. Twelve studies were randomised controlled trials (RCT), two were prospective cohort studies (PCS), one study was both a RCT and a PCS, six were interrupted time series and two were controlled before and after (CBA) studies. The RCTs had an overall low risk of bias, along with the ITS (apart from the dimension &#039;formal test of trend&#039;), and the PCS had overall good quality, apart from the description of loss to follow-up by exposure.Self reported or biomarker-assessed illicit drug use was measured with an array of published and unpublished scales making comparisons difficult. Pooled results of five RCTs (N = 5470) show no effect of media campaign intervention (standardised mean difference (SMD) -0.02; 95% confidence interval (CI) -0.15 to 0.12).We also pooled five ITS studies (N = 26,405) focusing specifically on methamphetamine use. Out of four pooled estimates (two endpoints measured in two age groups), there was evidence of a reduction only in past-year prevalence of methamphetamine use among 12 to 17 years old.A further five studies (designs = one RCT with PCS, two PCS, two ITS, one CBA, N = 151,508), which could not be included in meta-analyses, reported a drug use outcome with varied results including a clear iatrogenic effect in one case and reduction of use in another.

**Authors&#039; conclusions:** 
Overall the available evidence does not allow conclusions about the effect of media campaigns on illicit drug use among young people. We conclude that further studies are needed.
AN  - CD009287
AU  - Ferri,
AU  - M.
AU  - Allara,
AU  - E.
AU  - Bo,
AU  - A.
AU  - Gasparrini,
AU  - A.
AU  - Faggiano,
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009287.pub2
KW  - Mass Media
KW  - Street Drugs
KW  - Australia
KW  - Canada
KW  - Health Promotion [methods]
KW  - Prospective Studies
KW  - Randomized Controlled Trials as Topic
KW  - Retrospective Studies
KW  - Substance-Related Disorders [prevention &amp; control]
KW  - United States
KW  - Humans[checkword]
KW  - Addictn
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Media campaigns for the prevention of illicit drug use in young people
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009287.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009287.pub2/asset/CD009287.pdf?v=1&amp;t=iw7k352q&amp;s=b500028b62d3be361f7165e24382e2232c98a3fa
ER  -
TY  - JOUR
AB  - Across the globe, social workers serve schools in a variety of capacities, providing services such as skills training; individual, group, and family counseling; crisis intervention; home visits; parent support and education; and advocacy for students, families, and school systems. To date, no synthesis of the literature exists examining tier 1 and tier 2 cross-national school-based social work interventions. Therefore, the purpose of this systematic review was twofold: (1) to identify tier 1 and tier 2 school-based interventions that involve social workers and (2) to examine the extent to which the interventions are efficacious with school-based youths. A computerized search with inclusion and exclusion criteria was conducted using several databases. Eighteen studies were included for the final sample in this review. Effect sizes were calculated for all outcomes to determine magnitude of treatment effect.
AU  - Allen-Meares,
AU  - P.
AU  - Montgomery,
AU  - K.
AU  - L.
AU  - Kim,
AU  - J.
AU  - S.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1093/sw/swt022
KW  - Adolescent
KW  - Aggression
KW  - Child
KW  - Depression/th [Therapy]
KW  - Humans
KW  - *Mental Health Services
KW  - Reproductive Health
KW  - *School Health Services
KW  - Self Concept
KW  - *Social Work/mt [Methods]
L1  - internal-pdf://3848682906/Allen-Meares 2013 (1).pdf
N1  - Social Work. 58(3):253-62, 2013 Jul.Journal ArticleReviewSystematic Review
PY  - 2013
SP  - 253-62
TI  - School-based social work interventions: a cross-national systematic review. [Review]
VL  - 1
ER  -
TY  - JOUR
AB  - Many children with pervasive developmental disorders (PDD) exhibit behaviors and symptoms of attention-deficit/hyperactivity disorder (ADHD). 

We sought to determine the relative efficacy of medications for treating ADHD symptoms in children with PDD by identifying all double-blind, randomized, placebo-controlled trials examining the efficacy of medications for treating ADHD symptoms in children with PDD. 

We located seven trials involving 225 children. A random effects meta-analysis of four methylphenidate trials showed methylphenidate to be effective for treating ADHD symptoms in children with PDD (ES = .67). 

Several adverse events were greater for children were taking methylphenidate compared to placebo. An individual trial of clonidine and two trials of atomoxetine suggest these agents may also be effective in treating ADHD symptoms in children with PDD.
AD  - [Reichow, Brian; Volkmar, Fred R.; Bloch, Michael H.] Yale Univ, Sch Med, Ctr Child Study, New Haven, CT 06519 USA. Reichow, B (reprint author), Yale Univ, Sch Med, Ctr Child Study, 230 South Frontage Rd, New Haven, CT 06519 USA. brian.reichow@yale.edu
AN  - WOS:000324341500018
AU  - Reichow,
AU  - B.
AU  - Volkmar,
AU  - F.
AU  - R.
AU  - Bloch,
AU  - M.
AU  - H.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10803-013-1793-z
J2  - J. Autism Dev. Disord.
KW  - Autism Pervasive developmental disorder Attention deficit/hyperactivity disorder Methylphenidate Meta-analysis Atomoxetine Clonidine ADHD ASD Autism spectrum disorder PDD PDD-NOS AUTISM-SPECTRUM DISORDERS DEFICIT HYPERACTIVITY DISORDER PSYCHIATRIC-DISOR
L1  - internal-pdf://4177639935/Reichow-2013-Systematic Review and Meta-analys.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 217FD Times Cited: 6 Cited Reference Count: 41 Reichow, Brian Volkmar, Fred R. Bloch, Michael H. 6 SPRINGER/PLENUM PUBLISHERS NEW YORK J AUTISM DEV DISORD
PY  - 2013
SP  - 2435-2441
T2  - Journal of Autism and Developmental Disorders
TI  - Systematic Review and Meta-analysis of Pharmacological Treatment of the Symptoms of Attention-Deficit/Hyperactivity Disorder in Children with Pervasive Developmental Disorders
UR  - &lt;Go to ISI&gt;://WOS:000324341500018http://media.proquest.com/media/pq/classic/doc/3073716241/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Reichow%2C+Brian%3BVolkmar%2C+Fred+R%3BBloch%2C+Michael+H&amp;cit%3Atitle=Systematic+Review+and+Meta-analysis+of+Pharmacological+Treatment+of+...&amp;cit%3Apub=Journal+of+Autism+and+Developmental+Disorders&amp;cit%3Avol=43&amp;cit%3Aiss=10&amp;cit%3Apg=2435&amp;cit%3Adate=Oct+2013&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYxOTA4MDgyNDgzODo5NDM0NjkSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNDg0MDEyCjE0MzMwNzgwOTY6DURvY3VtZW50SW1hZ2VCATBSBk9ubGluZVoCRlRiA1BGVGoKMjAxMy8xMC8wMXIKMjAxMy8xMC8zMXoAggEpUC0xMDAwMjczLTMxMDc1LUNVU1RPTUVSLTEwMDAwMTU3LTExMTUxMTKSAQZPbmxpbmXKAQdFbmROb3Rl0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCKE9TOkVNUy1QZGZEb2NWaWV3QmFzZS1nZXRNZWRpYVVybEZvckl0ZW3KAg9BcnRpY2xlfEZlYXR1cmXSAgFZ4gIBTvICAA%3D%3D&amp;_s=4dJ3zmQjYwVI2wUOlvvnIyMuzFU%3D
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787525/pdf/nihms-453236.pdf
VL  - 43
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Use of alcohol and illicit drugs by adolescents is an important problem worldwide. 

**OBJECTIVE: **
To undertake a systematic review of mentoring in preventing/reducing adolescents&#039; alcohol and drug use. 

**DATA SOURCES: **
We searched 8 multidisciplinary electronic databases, the gray literature, and reference lists of included studies.

** STUDY ELIGIBILITY CRITERIA, PARTICIPANTS, AND INTERVENTIONS: **
Randomized controlled trials (RCTs) of mentoring in adolescents to prevent/reduce alcohol or drug use. 

**RESULTS:** 
Six RCTs were included in this review. Four RCTs provided evidence on mentoring and alcohol use. The 2 that could be pooled showed less alcohol use by mentored youth. Six RCTs on mentoring and drug use were identified, 2 of which provided some evidence of the effect of mentoring in reducing drug use. 

**LIMITATIONS: **Only 1 RCT was at low risk of bias for randomization. None of the studies stated they concealed allocation. Of the 6 included studies, 1 was at high risk and 5 at unclear risk for attrition. 

**CONCLUSIONS AND IMPLICATIONS OF KEY FINDINGS: **
Four RCTs provided evidence on mentoring and alcohol use, and the 2 that could be pooled showed less use by mentored youth. The 6 RCTs that provided evidence on drug use could not be pooled. Two did provide some evidence that mentoring is associated with less drug use. Very few well-designed studies evaluate the effects of mentoring on adolescent drug and alcohol use.
AD  - [Thomas, Roger E.] Dept Family Med, Calgary, AB, Canada. [Lorenzetti, Diane L.] Dept Community Hlth Sci, Calgary, AB, Canada. [Spragins, Wendy] Univ Calgary, Calgary, AB T2N 4N1, Canada. Thomas, RE (reprint author), Univ Calgary, Dept Family Med, Hlth Sci Ctr, G012,3330 Hosp Dr NW, Calgary, AB T2N 4N1, Canada. rthomas@ucalgary.ca
AN  - WOS:000322058600003
AU  - Thomas,
AU  - R.
AU  - E.
AU  - Lorenzetti,
AU  - D.
AU  - L.
AU  - Spragins,
AU  - W.
DA  - Jul-Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.acap.2013.03.007
J2  - Acad. Pediatr.
KW  - adolescents alcohol drinking children mentors substance-related disorders SCHOOL-BASED PREVENTION PROGRAM TRIAL YOUTH DEPENDENCE MISUSE IMPACT ABUSE Pediatrics
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 186QG Times Cited: 0 Cited Reference Count: 26 Thomas, Roger E. Lorenzetti, Diane L. Spragins, Wendy Canadian Tobacco Control Research Initiative A new literature search was undertaken through January 27,2013, and the original review updated and rewritten: Thomas RE, Lorenzetti D, Spragins W. Mentoring adolescents to prevent drug and alcohol use. Cochrane Database of Systematic Reviews 2011;(11):CD007381. Funded in part by a grant from the Canadian Tobacco Control Research Initiative. ELSEVIER SCIENCE INC NEW YORK ACAD PEDIATR
PY  - 2013
SP  - 292-299
T2  - Academic Pediatrics
TI  - Systematic Review of Mentoring to Prevent or Reduce Alcohol and Drug Use by Adolescents
UR  - &lt;Go to ISI&gt;://WOS:000322058600003http://ac.els-cdn.com/S1876285913000624/1-s2.0-S1876285913000624-main.pdf?_tid=bbc587aa-167c-11e5-8b67-00000aab0f27&amp;acdnat=1434716248_09e6deb0540f9eea22667bba360807fd
VL  - 13
ER  -
TY  - JOUR
AB  - **Objective: **
To evaluate the effectiveness of current medical and psychological interventions for individuals at risk of sexually abusing children, both in known abusers and those at risk of abusing. 

**Design: **
Systematic review of interventions designed to prevent reoffending among known abusers and prevention for individuals at risk of sexually abusing children. Randomised controlled trials and prospective observational studies were eligible. Primary outcomes were arrests, convictions, breaches of conditions, and self reported sexual abuse of children after one year or more. 

**Results: **
After review of 1447 abstracts, we retrieved 167 full text studies, and finally included eight studies with low to moderate risk of bias. We found weak evidence for interventions aimed at reducing reoffending in identified sexual abusers of children. For adults, evidence from five trials was insufficient regarding both benefits and risks with psychological treatment and pharmacotherapy. For adolescents, limited evidence from one trial suggested that multisystemic therapy prevented reoffence (relative risk 0.18, 95% confidence interval 0.04 to 0.73); lack of adequate research prevented conclusions about effects of other treatments. Evidence was also inadequate regarding effectiveness of treatment for children with sexual behavioural problems in the one trial identified. Finally, we found no eligible research on preventive methods for adults and adolescents who had not sexually abused children but were at higher risk of doing so (such as those with paedophilic sexual preference). 

**Conclusion: **
There are major weaknesses in the scientific evidence, particularly regarding adult men, the main category of sexual abusers of children. Better coordinated and funded high quality studies including several countries are urgently needed. Until conclusive evidence is available, realistic clinical strategies might involve reduction of specific risk factors for sex crimes, such as sexual preoccupation, in abusers at risk of reoffending.
AD  - (Langstrom) Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE-171 77 Stockholm, Sweden (Langstrom) Swedish Prison and Probation Administration, Norrkoping, Sweden (Enebrink) Department of Clinical Neurosciences, Division of Psychology, Karolinska Institutet, Box 281, SE-171 77 Stockholm, Sweden (Lauren) Stockholm County Council, Stockholm, Sweden (Lindblom, Werko) Swedish Council on Health Technology Assessment (SBU), Stockholm, Sweden (Lindblom, Werko) LIME, Karolinska Institutet, SE-106 91, Stockholm, Sweden (Karl Hanson) Public Safety Canada, Ottawa, ON, Canada N. Langstrom, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE-171 77 Stockholm, Sweden. E-mail: niklas.langstrom@ki.se
AN  - 2013600584
AU  - Langstrom,
AU  - N.
AU  - Enebrink,
AU  - P.
AU  - Lauren,
AU  - E.
AU  - M.
AU  - Lindblom,
AU  - J.
AU  - Werko,
AU  - S.
AU  - Karl
AU  - Hanson,
AU  - R.
DA  - 14 Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmj.f4630
DP  - Ovid Technologies
KW  - article behavior therapy child child sexual abuse clinical effectiveness cognitive therapy detention evidence based medicine group therapy high risk population human motivational interviewing observational study outcome assessment pedophilia disorder pr
LA  - English
PY  - 2013
T2  - BMJ (Online)
TI  - Preventing sexual abusers of children from reoffending: Systematic review of medical and psychological interventions
UR  - http://www.bmj.com/highwire/filestream/657110/field_highwire_article_pdf/0/bmj.f4630 http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed11&amp;AN=2013600584 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1136%2Fbmj.f4630&amp;issn=1756-1833&amp;isbn=&amp;volume=347&amp;issue=7924&amp;spage=f4630&amp;pages=&amp;date=2013&amp;title=BMJ+%28Online%29&amp;atitle=Preventing+sexual+abusers+of+children+from+reoffending%3A+Systematic+review+of+medical+and+psychological+interventions&amp;aulast=Langstrom&amp;pid=%3Cauthor%3ELangstrom+N.%3C%2Fauthor%3E%3CAN%3E2013600584%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3Ehttp://www.bmj.com/content/bmj/347/bmj.f4630.full.pdf
VL  - 347
ER  -
TY  - JOUR
AB  - This study aims to review the evidence for the efficacy of risperidone in the treatment of disruptive behavioural disorders (DBDs) in children and adolescents. 

Established databases were searched using the terms &#039;Risperidone and efficacy and children&#039; and &#039;Risperidone and efficacy and adolescents&#039;. Randomised, double-blind controlled studies were retained for analysis. Janseen-Cilag was contacted to identify any unpublished studies. 

Quality of studies was measured using Jadad scores. Seven studies of 657 subjects with a mean age of 9.9 years (SD= 2.0) (range 4-18 years) were identified. Only one study was judged to use the highest quality of methodology according to the Jadad score. 

Patients with DBD who were treated with risperidone showed clinical improvement compared with placebo. Weight gain, somnolence and gastrointestinal complaints were common. Risperidone was found to be efficacious in reducing symptoms in children and adolescents with DBD. 

However, studies were mostly of short duration and had deficiencies in the descriptions of blinding and randomisation. Research using rigorous methodology examining the long-term outcomes of efficacy and safety are required to inform clinicians and families of the therapeutic benefits and risks of risperidone in this clinical population.

Copyright &copy; 2011 The Authors. Journal of Paediatrics and Child Health &copy; 2011 Paediatrics and Child Health Division (Royal Australasian College of Physicians).
AD  - Duhig,Michael J. Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Queensland, Australia.
AN  - 22050179
AU  - Duhig,
AU  - M.
AU  - J.
AU  - Saha,
AU  - S.
AU  - Scott,
AU  - J.
AU  - G.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1440-1754.2011.02200.x.
DP  - Ovid Technologies
J2  - J Paediatr Child Health
KW  - Adolescent *Antipsychotic Agents/tu [Therapeutic Use] Attention Deficit and Disruptive Behavior Disorders/di [Diagnosis] *Attention Deficit and Disruptive Behavior Disorders/dt [Drug Therapy] Child Humans Psychological Tests Randomized Controlled Trials
LA  - English
M3  - Review
N1  - Duhig, Michael J Saha, Sukanta Scott, James G
PY  - 2013
SP  - 19-26
T2  - Journal of Paediatrics &amp; Child Health
TI  - Efficacy of risperidone in children with disruptive behavioural disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22050179
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22050179&amp;id=doi:10.1111%2Fj.1440-1754.2011.02200.x&amp;issn=1034-4810&amp;isbn=&amp;volume=49&amp;issue=1&amp;spage=19&amp;pages=19-26&amp;date=2013&amp;title=Journal+of+Paediatrics+%26+Child+Health&amp;atitle=Efficacy+of+risperidone+in+children+with+disruptive+behavioural+disorders.&amp;aulast=Duhig&amp;pid=%3Cauthor%3EDuhig+MJ%3C%2Fauthor%3E%3CAN%3E22050179%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1440-1754.2011.02200.x/asset/jpc2200.pdf?v=1&amp;t=ib3ifzej&amp;s=970b0f71390bd2b7c6976d25215c6a7ee157d514
VL  - 49
ER  -
TY  - JOUR
AB  - **Objective: **
To evaluate the efficacy of parenting interventions on child and parent behavioral and emotional outcomes for parents of children with traumatic brain injury (TBI).

**Methods: **
Systematic searches of 5 databases. Included studies were assessed for quality, and relevant data were extracted and collated. 

**Results: **
Eight articles met inclusion criteria, reporting 6 trials of interventions involving parent training for parents of children with TBI. Only 1 pre-post study trialed a version of a traditional parenting intervention. The remaining studies involved a multicomponent family problem-solving intervention. Each trial found a statistically significant intervention effect for at least 1 outcome measure. 

**Conclusions: **
Interventions that train parents may be a useful approach to alleviate behavioral and emotional disturbances after pediatric TBI. Some evidence suggests that these interventions may help to improve parenting skill and adjustment. However, all identified studies included interventions with multiple treatment components, so the effects attributable to parent training alone remain undetermined. Further quality trials are needed to assess the unique effectiveness of parenting interventions in this population.
AD  - [Brown, Felicity Louise; Whittingham, Koa; Sofronoff, Kate] Univ Queensland, Sch Psychol, Brisbane, Qld 4072, Australia. [Brown, Felicity Louise; Whittingham, Koa; Boyd, Roslyn] Univ Queensland, Sch Med, Queensland Cerebral Palsy &amp; Rehabil Res Ctr, Brisbane, Qld 4072, Australia. [Brown, Felicity Louise; Whittingham, Koa; Boyd, Roslyn] Univ Queensland, Queensland Childrens Med Res Inst, Brisbane, Qld 4072, Australia. Brown, FL (reprint author), Univ Queensland, Sch Psychol, Brisbane, Qld 4072, Australia. f.brown@psy.uq.edu.au
AN  - WOS:000330364600081
AU  - Brown,
AU  - F.
AU  - L.
AU  - Whittingham,
AU  - K.
AU  - Boyd,
AU  - R.
AU  - Sofronoff,
AU  - K.
DA  - Sep-Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/HTR.0b013e318245fed5
J2  - J. Head Trauma Rehabil.
KW  - brain injury intervention outcome parenting systematic review BEHAVIORAL FAMILY INTERVENTION PROBLEM-SOLVING INTERVENTION PRELIMINARY EFFICACY YOUNG-CHILDREN TRIPLE P REHABILITATION PROGRAM ADOLESCENTS EPIDEMIOLOGY PREDICTORS Clinical Neurology Rehabili
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 298ZU Times Cited: 1 Cited Reference Count: 42 Brown, Felicity Louise Whittingham, Koa Boyd, Roslyn Sofronoff, Kate Whittingham, Koa/C-6766-2009; Boyd, Roslyn/A-4498-2011 Whittingham, Koa/0000-0002-5344-9907; Boyd, Roslyn/0000-0002-4919-5975 Queensland Children&#039;s Medical Research Institute; National Health and Medical Research Council Ms Brown received a Queensland Children&#039;s Medical Research Institute PhD science scholarship. Dr Whittingham received a National Health and Medical Research Council Training fellowship. Dr Boyd received a National Health and Medical Research Council Career Development award. 1 LIPPINCOTT WILLIAMS &amp; WILKINS PHILADELPHIA J HEAD TRAUMA REHAB
PY  - 2013
SP  - 349-360
T2  - Journal of Head Trauma Rehabilitation
TI  - A Systematic Review of Parenting Interventions for Traumatic Brain Injury: Child and Parent Outcomes
UR  - &lt;Go to ISI&gt;://WOS:000330364600081http://graphics.tx.ovid.com/ovftpdfs/FPDDNCLBFDFJAN00/fs047/ovft/live/gv031/00001199/00001199-201309000-00002.pdf
UR  - https://insights.ovid.com/pubmed?pmid=22588359
VL  - 28
ER  -
TY  - JOUR
AB  - **Background:** 
Telephone communication is increasingly being accepted as a useful form of support within health care. There is some evidence that telephone support may be of benefit in specific areas of maternity care such as to support breastfeeding and for women at risk of depression. There is a plethora of telephone-based interventions currently being used in maternity care. It is therefore timely to examine which interventions may be of benefit, which are ineffective, and which may be harmful.

**Objectives:** 
To assess the effects of telephone support during pregnancy and the first six weeks post birth, compared with routine care, on maternal and infant outcomes.Search methods: We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (23 January 2013) and reference lists of all retrieved studies.

**Selection criteria:** 
We included randomised controlled trials, comparing telephone support with routine care or with another supportive intervention aimed at pregnant women and women in the first six weeks post birth.

**Data collection and analysis:** 
Three review authors independently assessed studies identified by the search strategy, carried out data extraction and assessed risk of bias. Data were entered by one review author and checked by a second. Where necessary, we contacted trial authors for further information on methods or results.

**Main results:** 
We have included data from 27 randomised trials involving 12,256 women. All of the trials examined telephone support versus usual care (no additional telephone support). We did not identify any trials comparing different modes of telephone support (for example, text messaging versus one-to-one calls). All but one of the trials were carried out in high-resource settings. The majority of studies examined support provided via telephone conversations between women and health professionals although a small number of trials included telephone support from peers. In two trials women received automated text messages. Many of the interventions aimed to address specific health problems and collected data on behavioural outcomes such as smoking cessation and relapse (seven trials) or breastfeeding continuation (seven trials). Other studies examined support interventions aimed at women at high risk of postnatal depression (two trials) or preterm birth (two trials); the rest of the interventions were designed to offer women more general support and advice.For most of our pre-specified outcomes few studies contributed data, and many of the results described in the review are based on findings from only one or two studies. Overall, results were inconsistent and inconclusive although there was some evidence that telephone support may be a promising intervention. Results suggest that telephone support may increase women&#039;s overall satisfaction with their care during pregnancy and the postnatal period, although results for both periods were derived from only two studies. There was no consistent evidence confirming that telephone support reduces maternal anxiety during pregnancy or after the birth of the baby, although results on anxiety outcomes were not easy to interpret as data were collected at different time points using a variety of measurement tools. There was evidence from two trials that women at high risk of depression who received support had lower mean depression scores in the postnatal period, although there was no clear evidence that women who received support were less likely to have a diagnosis of depression. Results from trials offering breastfeeding telephone support were also inconsistent, although the evidence suggests that telephone support may increase the duration of breastfeeding. There was no strong evidence that women receiving telephone support were less likely to be smoking at the end of pregnancy or during the postnatal period.For infant outcomes, such as preterm birth and infant birthweight, overall, there was little evidence. Where evidence was available, there were no clear differences between groups. Results from two trials suggest that babies whose mot e s received support may have been less likely to have been admitted to a neonatal intensive care unit (NICU), although it is not easy to understand the mechanisms underpinning this finding.

**Authors&#039; conclusions:** 
Despite some encouraging findings, there is insufficient evidence to recommend routine telephone support for women accessing maternity services, as the evidence from included trials is neither strong nor consistent. Although benefits were found in terms of reduced depression scores, breastfeeding duration and increased overall satisfaction, the current trials do not provide strong enough evidence to warrant investment in resources.
AN  - CD009338
AU  - Lavender,
AU  - T.
AU  - Richens,
AU  - Y.
AU  - Milan,
AU  - S.
AU  - J.
AU  - Smyth,
AU  - R.
AU  - M.
AU  - Dowswell,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009338.pub2
KW  - Telephone
KW  - Anxiety [prevention &amp; control]
KW  - Breast Feeding [statistics &amp; numerical data]
KW  - Depression, Postpartum [prevention &amp; control]
KW  - Postnatal Care [methods]
KW  - Pregnancy Complications [prevention &amp; control] [psychology]
KW  - Pregnancy Outcome
KW  - Prenatal Care [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Text Messaging
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Infant, Newborn[checkword]
KW  - Pregnancy[checkword]
KW  - Preg
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Telephone support for women during pregnancy and the first six weeks postpartum
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009338.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009338.pub2/asset/CD009338.pdf?v=1&amp;t=iw7l9hly&amp;s=46ef8fc807bf713fa0f30ba3ac7da9be94a5aa4d
ER  -
TY  - JOUR
AB  - **Background. **
Anorexia nervosa is a potentially deadly psychiatric illness that develops predominantly in females around puberty but is increasingly being recognized as also affecting boys and men and women across the lifespan. The aim of this environmental scan is to provide an overview of best practices in anorexia nervosa treatment across the age spectrum. 

**Method.**
A triangulation approach was used. First, a detailed review of randomized controlled trials (RCTs) for anorexia nervosa published between 1980 and 2011 was conducted; second, clinical practice guidelines were consulted and reviewed; third, information about RCTs currently underway was sourced. This approach facilitated a comprehensive overview, which addressed the extant evidence base, recent advances in evidence and improvements in treatment, and future directions. 

**Results. **
The evidence base for the treatment of anorexia nervosa is advancing, albeit unevenly. Evidence points to the benefit of family-based treatment for youth. For adults no specific approach has shown superiority and, presently, a combination of renourishment and psychotherapy such as specialist supportive clinical management, cognitive behavioral therapy, or interpersonal psychotherapy is recommended. RCTs have neither sufficiently addressed the more complex treatment approaches seen in routine practice settings, such as multidisciplinary treatment or level of care, nor specifically investigated treatment in ethnically diverse populations. Methodological challenges that hinder progress in controlled research for anorexia nervosa are explained. 

**Conclusions. **
The review highlights evidence-based and promising treatment modalities for anorexia nervosa and presents a triangulated analysis including controlled research, practice guidelines, and emerging treatments to inform and support clinical decision making.
AD  - [Watson, H. J.] Dept Hlth Western Australia, Ctr Clin Intervent, Perth, WA, Australia. [Watson, H. J.] Princess Margaret Hosp Children, Eating Disorders Program, Perth, WA, Australia. [Watson, H. J.] Univ Western Australia, Sch Paediat &amp; Child Hlth, Perth, WA 6009, Australia. [Bulik, C. M.] Univ N Carolina, Dept Psychiat, Chapel Hill, NC 27599 USA. [Bulik, C. M.] Univ N Carolina, Dept Nutr, Chapel Hill, NC 27599 USA. Bulik, CM (reprint author), Univ N Carolina, Dept Psychiat, 101 Manning Dr,CB 7160, Chapel Hill, NC 27599 USA. cbulik@med.unc.edu
AN  - WOS:000326944900002
AU  - Watson,
AU  - H.
AU  - J.
AU  - Bulik,
AU  - C.
AU  - M.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1017/S0033291712002620
J2  - Psychol. Med.
KW  - Anorexia nervosa antidepressants antipsychotics clinical trials cognitive behavioral therapy eating disorders family therapy family-based treatment reviews systematic reviews treatment RANDOMIZED CONTROLLED-TRIAL FAMILY-BASED TREATMENT EATING-DISORDERS
L1  - internal-pdf://4062717538/Watson-2013-Update on the treatment of anorexi.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 251QL Times Cited: 7 Cited Reference Count: 97 Watson, H. J. Bulik, C. M. 7 CAMBRIDGE UNIV PRESS NEW YORK PSYCHOL MED
PY  - 2013
SP  - 2477-2500
T2  - Psychological Medicine
TI  - Update on the treatment of anorexia nervosa: review of clinical trials, practice guidelines and emerging interventions
UR  - &lt;Go to ISI&gt;://WOS:000326944900002http://media.proquest.com/media/pq/classic/doc/3119739831/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Watson%2C+H+J%3BBulik%2C+C+M&amp;cit%3Atitle=Update+on+the+treatment+of+anorexia+nervosa%3A+review+of+clinical+...&amp;cit%3Apub=Psychological+Medicine&amp;cit%3Avol=43&amp;cit%3Aiss=12&amp;cit%3Apg=2477&amp;cit%3Adate=Dec+2013&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYxOTEwMzYyOTY3Njo2NjQ1NzgSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFMzU3NTMyCjE0NDg5ODQ4OTQ6DURvY3VtZW50SW1hZ2VCATBSBk9ubGluZVoCRlRiA1BGVGoKMjAxMy8xMi8wMXIKMjAxMy8xMi8zMXoAggEpUC0xMDAwMjczLTMxMDc1LUNVU1RPTUVSLTEwMDAwMTU3LTExMTUxMTKSAQZPbmxpbmXKAQdFbmROb3Rl0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCKE9TOkVNUy1QZGZEb2NWaWV3QmFzZS1nZXRNZWRpYVVybEZvckl0ZW3KAg9BcnRpY2xlfEZlYXR1cmXSAgFZ4gIBTvICAA%3D%3D&amp;_s=TA%2FTAOW9urlDnPk40vScrauNWM8%3D
UR  - https://www.cambridge.org/core/journals/psychological-medicine/article/update-on-the-treatment-of-anorexia-nervosa-review-of-clinical-trials-practice-guidelines-and-emerging-interventions/5A329A97727E16B16FFD573277430EB0
VL  - 43
ER  -
TY  - JOUR
AB  - The purpose of this article is to clarify the role of teacher training initiatives aimed at improving social, emotional and behavioural outcomes of primary school aged children through improved classroom management. 

Systematic searches were conducted using a range of electronic databases from inception up to September 2011. 

Included studies were controlled trials that described training provided to teachers in classroom management techniques designed to improve primary school children&#039;s behavioural and social outcomes. 

Study selection and appraisal of quality were carried out by two researchers and a narrative synthesis was carried out. A total of 14 studies were included involving 8 interventions. 

Results show that statistically significant effects are limited, with only 20 outcomes showing significant effects in the desired direction. 

Effect sizes ranged from g = -0.17 (95% CI: -0.32, -0.02) to g = 1.88 (95% CI: 0.55, 3.21). Overall, the programmes indicate an improvement in some outcomes of interest. 

However, further research into the implementation and comparative effectiveness of such programmes is needed before implications for educational policy and practice can be established.
AD  - [Whear, R.; Thompson-Coon, J.; Boddy, K.; Stein, K.] Univ Exeter, Exeter EX4 4QJ, Devon, England. [Ford, T.] Peninsula Coll Med &amp; Dent, Plymouth, Devon, England. [Racey, D.] Torbay NHS Trust, Torquay, England. Whear, R (reprint author), Peninsula Coll Med &amp; Dent, PenCLAHRC, Veysey Bldg,Salmonpool Lane, Exeter EX2 4SG, Devon, England. rebecca.whear@pms.ac.uk
AN  - WOS:000330177800010
AU  - Whear,
AU  - R.
AU  - Thompson-Coon,
AU  - J.
AU  - Boddy,
AU  - K.
AU  - Ford,
AU  - T.
AU  - Racey,
AU  - D.
AU  - Stein,
AU  - K.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/01411926.2011.650680
J2  - Br. Educ. Res. J.
KW  - teacher training primary school review behaviour social emotional DISRUPTIVE BEHAVIOR MENTAL-HEALTH CLASSROOM BURNOUT IMPLEMENTATION ADOLESCENCE ACHIEVEMENT COMPETENCE ADJUSTMENT PROGRAM Education &amp; Educational Research
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 296IF Times Cited: 2 Cited Reference Count: 57 Whear, R. Thompson-Coon, J. Boddy, K. Ford, T. Racey, D. Stein, K. 2 WILEY-BLACKWELL HOBOKEN BRIT EDUC RES J
PY  - 2013
SP  - 383-420
T2  - British Educational Research Journal
TI  - The effect of teacher-led interventions on social and emotional behaviour in primary school children: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000330177800010http://onlinelibrary.wiley.com/store/10.1080/01411926.2011.650680/asset/berj3061.pdf?v=1&amp;t=ib7m0mnc&amp;s=b8d5e1f746d33cab7b415e24982fe1c73ca7cf53
VL  - 39
ER  -
TY  - JOUR
AB  - **Background:** 
Adult and adolescent congenital heart disease is increasing in prevalence as better medical care means more children are surviving to adulthood. People with chronic disease often also experience depression. There are several non-pharmacological treatments that might be effective in treating depression and improving quality of life for adults and young adults with congenital heart disease. The aim of this review was to assess the effects of treatments such as psychotherapy, cognitive behavioural therapies and talking therapies for treating depression in this population.

**Objectives:** 
To update the previous review on the effects (both harms and benefits) of psychological interventions for treating depression in young adults and adults with congenital heart disease. Psychological interventions include cognitive behavioural therapy, psychotherapy, or &#039;talking/counselling&#039; therapy for depression.

**Search methods:** 
We updated the searches of the Cochrane Central Register of Controlled Trials (CENTRAL) on The Cochrane Library (Issue 1, 2013), MEDLINE (OVID, 1946 to January week 4 2013), EMBASE (OVID, 1980 to 2013 week 05), PsycINFO (OVID, 1806 to January week 5 2013), the Database of Abstracts of Reviews of Effectiveness (DARE) on The Cochrane Library (Issue 1, 2013), BIOSIS (Thomson Reuters, 1969 to 21 February 2013), and CINAHL (January 1980 to February 2013) on 5 February 2013. We did not search abstracts from national and international cardiology and psychology conferences and dissertation abstracts for this update. No language restrictions were applied.

**Selection criteria:** 
Randomised controlled trials comparing psychological interventions with no intervention for people over 15 years with depression who have congenital heart disease.

**Data collection and analysis:** 
Two review authors independently screened titles and abstracts of studies that were potentially relevant to the review. We rejected studies that were clearly ineligible. Two review authors independently assessed the abstracts or full papers for inclusion criteria. We sought further information from the authors where papers contained insufficient information to make a decision about eligibility.

**Main results:** 
We did not identify any randomised controlled trials that met the inclusion criteria.

**Authors&#039; conclusions:**
Depression is common in people with congenital heart disease and can exacerbate the physical consequences of the illness. There are effective pharmacological and non-pharmacological treatments for depression, but we have not been able to identify any trials showing the effectiveness of non-pharmacological treatments. A well-designed randomised controlled trial is needed to assess the effects of psychological interventions for depression in congenital heart disease.
AN  - CD004372
AU  - Lane,
AU  - D.
AU  - A.
AU  - Millane,
AU  - T.
AU  - A.
AU  - Lip,
AU  - G.
AU  - Y.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004372.pub2
KW  - Cognitive Therapy [methods]
KW  - Depression [therapy]
KW  - Heart Diseases [congenital] [psychology]
KW  - Psychotherapy [methods]
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Humans[checkword]
KW  - Young Adult[checkword]
KW  - Vasc
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological interventions for depression in adolescent and adult congenital heart disease
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004372.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004372.pub2/asset/CD004372.pdf?v=1&amp;t=iw7kt0wo&amp;s=ca4d0de40f43a5865952626fc1bd9c173d659cb3
ER  -
TY  - JOUR
AB  - Pre- and postcharge diversion programs have been used as a formal intervention strategy for youth offenders since the 1970s. 

This meta-analysis was conducted to shed some light on whether diversion reduces recidivism at a greater rate than traditional justice system processing and to explore aspects of diversion programs associated with greater reductions in recidivism. 

Forty-five diversion evaluation studies reporting on 73 programs were included in the meta-analysis. 

The results indicated that diversion is more effective in reducing recidivism than conventional judicial interventions. Moderator analysis revealed that both study- and program-level variables influenced program effectiveness. 

Of particular note was the relationship between program-level variables (e.g., referral level) and the risk level targeted by programs (e.g., low or medium/high). Further research is required implementing strong research designs and exploring the role of risk level on youth diversion effectiveness. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - Wilson, Holly A.: Holly_Wilson14@hotmail.com Wilson, Holly A.: Department of Psychology, Ryerson University, Jorgenson Hall, 350 Victoria Street, Toronto, ON, Canada, M5B 2K3, Holly_Wilson14@hotmail.com Wilson, Holly A.: Ryerson University, Toronto, ON, Canada Hoge, Robert D.: Carleton University, Ottawa, ON, Canada
AN  - 2013-12174-002
AU  - Wilson,
AU  - H.
AU  - A.
AU  - Hoge,
AU  - R.
AU  - D.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0093854812451089
DP  - Ovid Technologies
KW  - youth diversion programs, recidivism, justice system, youth offenders, intervention *Criminal Justice *Intervention *Juvenile Delinquency *Recidivism Criminal Rehabilitation &amp; Penology [3386] Human
LA  - English
M3  - Meta Analysis
PY  - 2013
SP  - 497-518
T2  - Criminal Justice and Behavior
TI  - The effect of youth diversion programs on recidivism: A meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-12174-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=0093-8548&amp;isbn=&amp;volume=40&amp;issue=5&amp;spage=497&amp;pages=497-518&amp;date=2013&amp;title=Criminal+Justice+and+Behavior&amp;atitle=The+effect+of+youth+diversion+programs+on+recidivism%3A+A+meta-analytic+review.&amp;aulast=Wilson&amp;pid=%3Cauthor%3EWilson%2C+Holly+A%3C%2Fauthor%3E%3CAN%3E2013-12174-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 40
ER  -
TY  - JOUR
AB  - Children with developmental disabilities are at higher risk for internalizing and externalizing behavioral problems than children in the general population. 

Effective prevention and treatment programs are necessary to reduce the burden of behavioral problems in this population. The current review identified 17 controlled trials of nine intervention programs for young children with developmental disabilities, with parent training the most common type of intervention in this population. 

Nearly all studies demonstrated medium to large intervention effects on child behavior post-intervention. Preliminary evidence suggests interventions developed for the general population can be effective for children with developmental disabilities and their families. 

A greater emphasis on the prevention of behavior problems in young children with developmental disabilities prior to the onset of significant symptoms or clinical disorders is needed. Multi-component interventions may be more efficacious for child behavior problems and yield greater benefits for parent and family adjustment.

Recommendations for future research directions are provided. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - M Petrenko, Christie L. M.: christie.petrenko@rochester.edu Petrenko, Christie L. M.: Mt. Hope Family Center, University of Rochester, 187 Edinburgh St., Rochester, NY, US, 14608, christie.petrenko@rochester.edu Petrenko, Christie L. M.: Mt. Hope Family Center, University of Rochester, Rochester, NY, US
AN  - 2013-04951-001
AU  - Petrenko,
AU  - C.
AU  - L.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821779/
DP  - Ovid Technologies
KW  - intervention programs, behavioral problems, young children, developmental disabilities, risk factors, parent training *Behavior Problems *Childhood Development *Developmental Disabilities *Parent Training *Program Development Intervention Prevention Ris
LA  - English
M3  - Literature Review
PY  - 2013
SP  - 651-679
T2  - Journal of Developmental and Physical Disabilities
TI  - A review of intervention programs to prevent and treat behavioral problems in young children with developmental disabilities
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-04951-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10882-013-9336-2&amp;issn=1056-263X&amp;isbn=&amp;volume=25&amp;issue=6&amp;spage=651&amp;pages=651-679&amp;date=2013&amp;title=Journal+of+Developmental+and+Physical+Disabilities&amp;atitle=A+review+of+intervention+programs+to+prevent+and+treat+behavioral+problems+in+young+children+with+developmental+disabilities.&amp;aulast=Petrenko&amp;pid=%3Cauthor%3EPetrenko%2C+Christie+L.+M%3C%2Fauthor%3E%3CAN%3E2013-04951-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10882-013-9336-2http://download.springer.com/static/pdf/897/art%253A10.1007%252Fs10882-013-9336-2.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10882-013-9336-2&amp;token2=exp=1435232558~acl=%2Fstatic%2Fpdf%2F897%2Fart%25253A10.1007%25252Fs10882-013-9336-2.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10882-013-9336-2*~hmac=a0b07a6cdbe3d6091ff35c33e116aff20e58af7583c8a552588d3ef939afc955
VL  - 25
ER  -
TY  - JOUR
AB  - **Background:** 
Iron deficiency and iron deficiency anaemia (IDA) are common in young children. It has been suggested that the lack of iron may have deleterious effects on children&#039;s psychomotor development and cognitive function. To evaluate the benefits of iron therapy on psychomotor development and cognitive function in children with IDA, a Cochrane review was carried out in 2001. This is an update of that review.

**Objectives:** 
To determine the effects of iron therapy on psychomotor development and cognitive function in iron deficient anaemic children less than three years of age.Search methods: We searched the following databases in April 2013: Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, CINAHL, PsycINFO, LILACS, ClinicalTrials.gov and World Health Organization International Clinical Trials Registry Platform (ICTRP). We also searched the reference lists of review articles and reports, and ran citation searches in the Science Citation Index for relevant studies identified by the primary search. We also contacted key authors.

**Selection criteria:** 
Studies were included if children less than three years of age with evidence of IDA were randomly allocated to iron or iron plus vitamin C versus a placebo or vitamin C alone, and assessment of developmental status or cognitive function was carried out using standardised tests by observers blind to treatment allocation.

**Data collection and analysis:** 
Two review authors independently screened titles and abstracts retrieved from the searches and assessed full-text copies of all potentially relevant studies against the inclusion criteria. The same review authors independently extracted data and assessed the risk of bias of the eligible studies. Data were analysed separately depending on whether assessments were performed within one month of beginning iron therapy or after one month.

**Main results:** 
We identified one eligible study in the update search that had not been included in the original review. In total, we included eight trials.Six trials, including 225 children with IDA, examined the effects of iron therapy on measures of psychomotor development and cognitive function within 30 days of commencement of therapy. We could pool data from five trials. The pooled difference in pre- to post-treatment change in Bayley Scale Psychomotor Development Index (PDI) between iron and placebo groups was -1.25 (95% confidence interval (CI) -4.56 to 2.06, P value = 0.65; I2 = 33% for heterogeneity, random-effects meta-analysis; low quality evidence) and in Bayley Scale Mental Development Index (MDI) was 1.04 (95% CI -1.30 to 3.39, P value = 0.79; I2 = 31% for heterogeneity, random-effects meta-analysis; low quality evidence).Two studies, including 160 randomised children with IDA, examined the effects of iron therapy on measures of psychomotor development and cognitive function more than 30 days after commencement of therapy. One of the studies reported the mean number of skills gained after two months of iron therapy using the Denver Developmental Screening Test. The intervention group gained 0.8 (95% CI -0.18 to 1.78, P value = 0.11, moderate quality of evidence) more skills on average than the control group. The other study reported that the difference in pre- to post-treatment change in Bayley Scale PDI between iron-treated and placebo groups after four months was 18.40 (95% CI 10.16 to 26.64, P value &lt; 0.0001; moderate quality evidence) and in Bayley Scale MDI was 18.80 (95% CI 10.17 to 27.43, P value &lt; 0.0001; moderate quality evidence).

**Authors&#039; conclusions:** 
There is no convincing evidence that iron treatment of young children with IDA has an effect on psychomotor development or cognitive function within 30 days after commencement of therapy. The effect of longer-term treatment remains unclear. There is an urgent need for further large randomised controlled trials with long-term follow-up.
AN  - CD001444
AU  - Wang,
AU  - B.
AU  - Zhan,
AU  - S.
AU  - Gong,
AU  - T.
AU  - Lee,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd001444.pub2
KW  - Anemia, Iron-Deficiency [drug therapy] [psychology]
KW  - Cognition [drug effects]
KW  - Iron Compounds [therapeutic use]
KW  - Psychomotor Performance [drug effects]
KW  - Randomized Controlled Trials as Topic
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Infant, Newborn[checkword]
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Iron therapy for improving psychomotor development and cognitive function in children under the age of three with iron deficiency anaemia
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001444.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD001444.pub2/asset/CD001444.pdf?v=1&amp;t=iw7jwso1&amp;s=d28c160b31896981e1df478ad5bd8be72ffa71bc
ER  -
TY  - JOUR
AB  - **Background **
The sexual abuse of children and adolescents is a significant worldwide problem. It is associated with a wide variety of negative psychological, social and physical consequences for the victims. These effects can often be seen immediately following sexual abuse, but they may manifest later on and sometimes only in adult life. There are a number of different interventions aimed at helping children and adolescents who have been sexually abused, and psychoanalytic/psychodynamic psychotherapy has a long-established tradition of being used for such victims. In this review, we set out to find the evidence for its effectiveness specifically in children and adolescents who have been sexually abused.

**Objectives **
To assess the effectiveness of psychoanalytic/psychodynamic psychotherapy for children and adolescents who have been sexually abused. 

**Search methods**
We searched the following databases in May 2013: CENTRAL, Ovid MEDLINE, Embase, PsycINFO, CINAHL, Sociological Abstracts, Social Science Citation Index, Conference Proceedings Citation Index - Social Science and Humanities, LILACS andWorldCat. We also searched three trials registers, checked the reference lists of relevant studies and contacted known experts.

**Selection criteria**
Randomised and quasi-randomised trials comparing psychoanalytic/psychodynamic psychotherapy with treatment as usual or no treatment/waiting list control for children and adolescents up to age of 18 who had experienced sexual abuse at any time prior to the intervention.

**Data collection and analysis** 
The review authors (BP and WT) independently screened search results to identify studies that met eligibility criteria. 

**Main results **
No studies were identified that met the inclusion criteria for this review.

**Authors&rsquo; conclusions**
There are no randomised and quasi-randomised trials that compare psychoanalytic/psychodynamic therapy with treatment as usual, no treatment or waiting list control for children and adolescents who have been sexually abused. As a result, we cannot draw any conclusions as to the effectiveness ofpsychoanalytic/psychodynamic psychotherapy for this population. This important gap emphasises the need for further research into the effectiveness of psychoanalytic/psychodynamic psychotherapy in this population. Such research should ideally be in the form of methodologically high-quality, large-scale randomised controlled trials. If these are not conducted, future systematic reviews on this subject may need to consider including other lower quality evidence in order to avoid overlooking important research.
AD  - [Parker, Ben] Priory Hosp Chelmsford, Adolescent Unit, Chelmsford CM1 7SJ, Essex, England. [Turner, William] Univ Bristol, Sch Policy Studies, Bristol, Avon, England. Parker, B (reprint author), Priory Hosp Chelmsford, Adolescent Unit, Stump Lane, Chelmsford CM1 7SJ, Essex, England. benparker@priorygroup.com
AN  - WOS:000322568300021
AU  - Parker,
AU  - B.
AU  - Turner,
AU  - W.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD008162.pub2
J2  - Cochrane Database Syst Rev.
KW  - PSYCHODYNAMIC PSYCHOTHERAPY COGNITIVE NEUROSCIENCE CHILDHOOD ABUSE METAANALYSIS GIRLS PSYCHOANALYSIS THERAPY PSYCHOPATHOLOGY INTERVENTIONS PERSPECTIVE Medicine, General &amp; Internal
L1  - internal-pdf://1961465844/Parker-2013-Psychoanalytic_psychodynamic psych.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 193OD Times Cited: 0 Cited Reference Count: 93 Parker, Ben Turner, William Centre for Gender Violence Research, School for Policy Studies, University of Bristol, UK; South West London and St Georges Mental Health NHS Trust, UK Internal sourcesCentre for Gender Violence Research, School for Policy Studies, University of Bristol, UK.South West London and St Georges Mental Health NHS Trust, UK. WILEY-BLACKWELL HOBOKEN COCHRANE DB SYST REV
PY  - 2013
SP  - 30
T2  - Cochrane Database of Systematic Reviews
TI  - Psychoanalytic/psychodynamic psychotherapy for children and adolescents who have been sexually abused
UR  - &lt;Go to ISI&gt;://WOS:000322568300021http://onlinelibrary.wiley.com/store/10.1002/14651858.CD008162.pub2/asset/CD008162.pdf?v=1&amp;t=ib7ud26j&amp;s=27ddb64ce66d1f7a3b6be8d2a7983e0a96a51dc0
ER  -
TY  - JOUR
AB  - **BACKGROUND AND OBJECTIVE: **
The &quot;synactive&quot; theory of neurobehavioral development forms the basis of the Newborn Individualized Developmental Care and Assessment Program (NIDCAP). Our objective was to assess the effectiveness of NIDCAP in improving outcomes in preterm infants. 

**METHODS: **
Medline, CINAHL, Embase, PsychInfo, The Cochrane Library, Pediatric Academic Societies&#039; Abstracts and Web of Science were searched in July 2010 and February 2012. The studies selected were randomized controlled trials testing the effectiveness of NIDCAP on medical and neurodevelopmental outcomes. The authors abstracted baseline characteristics of infants and outcomes. The risk of bias was assessed by using Cochrane criteria. RevMan 5.1 was used to synthesize data by the use of relative risk and risk difference for dichotomous outcomes and mean or standardized mean difference for continuous outcomes. 

**RESULTS: **
Eleven primary and 7 secondary studies enrolling 627 neonates were included, with 2 of high quality. The composite primary outcomes of death or major sensorineural disability at 18 months corrected age or later in childhood (3 trials, 302 children; relative risk 0.89 [95% confidence interval 0.61 to 1.29]) and survival free of disability at 18 months corrected age or later in childhood (2 trials, 192 infants; relative risk 0.97 [95% confidence interval 0.69 to 1.35]), were not significantly different between the NIDCAP and control groups. With the sensitivity analysis that excluded the 2 statistically heterogeneous outlying studies, there were no significant differences between groups for short-term medical outcomes. 

**CONCLUSIONS: **
This systematic review including 627 preterm infants did not find any evidence that NIDCAP improves long-term neurodevelopmental or short-term medical outcomes.
AD  - Ohlsson,Arne. Department of Paediatrics, University of Toronto, Ontario, Canada. aohlsson@mtsinai.on.ca
AN  - 23420913
AU  - Ohlsson,
AU  - A.,
AU  - Jacobs,
AU  - S.
AU  - E.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2012-2121
DP  - Ovid Technologies
J2  - Pediatrics
KW  - *Child Development/ph [Physiology] Humans Infant, Newborn *Infant, Premature/gd [Growth &amp; Development] *Neonatal Screening/mt [Methods] Neonatal Screening/st [Standards] Program Evaluation/mt [Methods] Program Evaluation/st [Standards] Randomized Contro
L1  - internal-pdf://3139908224/Ohlsson-2013-NIDCAP_ a systematic review and m.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Ohlsson, Arne Jacobs, Susan E Comment in: Pediatrics. 2013 Aug;132(2):e550; PMID: 23908320 Comment in: Pediatrics. 2013 Aug;132(2):e550-1; PMID: 23908321 Comment in: Pediatrics. 2013 Aug;132(2):e551-2; PMID: 23908322 Comment in: Pediatrics. 2013 Aug;132(2):e552-3; PMID: 23908323
PY  - 2013
SP  - e881-93
T2  - Pediatrics
TI  - NIDCAP: a systematic review and meta-analyses of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23420913 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23420913&amp;id=doi:10.1542%2Fpeds.2012-2121&amp;issn=0031-4005&amp;isbn=&amp;volume=131&amp;issue=3&amp;spage=e881&amp;pages=e881-93&amp;date=2013&amp;title=Pediatrics&amp;atitle=NIDCAP%3A+a+systematic+review+and+meta-analyses+of+randomized+controlled+trials.&amp;aulast=Ohlsson&amp;pid=%3Cauthor%3EOhlsson+A%3C%2Fauthor%3E%3CAN%3E23420913%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://pediatrics.aappublications.org/content/131/3/e881.full.pdf
UR  - http://pediatrics.aappublications.org/content/pediatrics/131/3/e881.full.pdf
VL  - 131
ER  -
TY  - JOUR
AB  - **Background:** 
Helping young people to avoid starting smoking is a widely endorsed public health goal, and schools provide a route to communicate with nearly all young people. School-based interventions have been delivered for close to 40 years.

**Objectives:** 
The primary aim of this review was to determine whether school smoking interventions prevent youth from starting smoking. Our secondary objective was to determine which interventions were most effective. This included evaluating the effects of theoretical approaches; additional booster sessions; programme deliverers; gender effects; and multifocal interventions versus those focused solely on smoking.

**Search methods:** 
We searched the Cochrane Central Register of Controlled Trials (CENTRAL), the Cochrane Tobacco Addiction Group&#039;s Specialised Register, MEDLINE, EMBASE, PsyclNFO, ERIC, CINAHL, Health Star, and Dissertation Abstracts for terms relating to school-based smoking cessation programmes. In addition, we screened the bibliographies of articles and ran individual MEDLINE searches for 133 authors who had undertaken randomised controlled trials in this area. The most recent searches were conducted in October 2012.

**Selection criteria:** 
We selected randomised controlled trials (RCTs) where students, classes, schools, or school districts were randomised to intervention arm(s) versus a control group, and followed for at least six months. Participants had to be youth (aged 5 to 18). Interventions could be any curricula used in a school setting to deter tobacco use, and outcome measures could be never smoking, frequency of smoking, number of cigarettes smoked, or smoking indices.

**Data collection and analysis:** 
Two reviewers independently assessed studies for inclusion, extracted data and assessed risk of bias. Based on the type of outcome, we placed studies into three groups for analysis: Pure Prevention cohorts (Group 1), Change in Smoking Behaviour over time (Group 2) and Point Prevalence of Smoking (Group 3).

**Main results:** 
One hundred and thirty-four studies involving 428,293 participants met the inclusion criteria. Some studies provided data for more than one group.Pure Prevention cohorts (Group 1) included 49 studies (N = 142,447). Pooled results at follow-up at one year or less found no overall effect of intervention curricula versus control (odds ratio (OR) 0.94, 95% confidence interval (CI) 0.85 to 1.05). In a subgroup analysis, the combined social competence and social influences curricula (six RCTs) showed a statistically significant effect in preventing the onset of smoking (OR 0.49, 95% CI 0.28 to 0.87; seven arms); whereas significant effects were not detected in programmes involving information only (OR 0.12, 95% CI 0.00 to 14.87; one study), social influences only (OR 1.00, 95% CI 0.88 to 1.13; 25 studies), or multimodal interventions (OR 0.89, 95% CI 0.73 to 1.08; five studies). In contrast, pooled results at longest follow-up showed an overall significant effect favouring the intervention (OR 0.88, 95% CI 0.82 to 0.96). Subgroup analyses detected significant effects in programmes with social competence curricula (OR 0.52, 95% CI 0.30 to 0.88), and the combined social competence and social influences curricula (OR 0.50, 95% CI 0.28 to 0.87), but not in those programmes with information only, social influence only, and multimodal programmes.Change in Smoking Behaviour over time (Group 2) included 15 studies (N = 45,555). At one year or less there was a small but statistically significant effect favouring controls (standardised mean difference (SMD) 0.04, 95% CI 0.02 to 0.06). For follow-up longer than one year there was a statistically nonsignificant effect (SMD 0.02, 95% CI -0.00 to 0.02).Twenty-five studies reported data on the Point Prevalence of Smoking (Group 3), though heterogeneity in this group was too high for data to be pooled.We were unable to analyse data for 49 studies (N = 152,544).Subgroup analyses (Pure Prevention cohorts only) demonstrated that at longest follow-up for all curricula combined, there was a significant effect favouring adult present r (OR 0.88, 95% CI 0.81 to 0.96). There were no differences between tobacco-only and multifocal interventions. For curricula with booster sessions there was a significant effect only for combined social competence and social influences interventions with follow-up of one year or less (OR 0.50, 95% CI 0.26 to 0.96) and at longest follow-up (OR 0.51, 95% CI 0.27 to 0.96). Limited data on gender differences suggested no overall effect, although one study found an effect of multimodal intervention at one year for male students. Sensitivity analyses for Pure Prevention cohorts and Change in Smoking Behaviour over time outcomes suggested that neither selection nor attrition bias affected the results.

**Authors&#039; conclusions:** 
Pure Prevention cohorts showed a significant effect at longest follow-up, with an average 12% reduction in starting smoking compared to the control groups. However, no overall effect was detected at one year or less. The combined social competence and social influences interventions showed a significant effect at one year and at longest follow-up. Studies that deployed a social influences programme showed no overall effect at any time point; multimodal interventions and those with an information-only approach were similarly ineffective.Studies reporting Change in Smoking Behaviour over time did not show an overall effect, but at an intervention level there were positive findings for social competence and combined social competence and social influences interventions.
AN  - CD001293
AU  - Thomas,
AU  - R.
AU  - E.
AU  - McLellan,
AU  - J.
AU  - Perera,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/ebch.1937
KW  - Program Evaluation
KW  - Health Promotion
KW  - Randomized Controlled Trials as Topic
KW  - School Health Services [standards]
KW  - Schools
KW  - Smoking [prevention &amp; control]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Tobacco
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - School-based programmes for preventing smoking
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001293.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD001293.pub3/asset/CD001293.pdf?v=1&amp;t=iw7l3djf&amp;s=dcbb0bb910ccc9d86eb4c6fed59a64dc03fbebd4
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
The US Agency for Healthcare Research and Quality sponsored a comparative effectiveness review of interventions for preschoolers at risk for attention-deficit/hyperactivity disorder (ADHD). 

**METHODS: **
Medline, Cochrane CENTRAL, Embase, PsycInfo, and Education Resources Information Center were searched from 1980 to November 24, 2011. Selected studies were comparative, and enrolled children &lt;6 years with clinically significant disruptive behavior, including ADHD. The interventions evaluated were parent behavior training (PBT), combined home and school/day care interventions, and methylphenidate use. Data were extracted by using customized software. Two independent raters evaluated studies as good, fair, or poor by using the Effective Public Health Practice Project Quality Assessment Tool for Quantitative Studies Risk of Bias. Overall strength of evidence (SOE) was rated for each intervention&#039;s effectiveness, accounting for study design, systematic error, consistency of results, directness of evidence, and certainty regarding outcome. 

**RESULTS:**
Fifty-five studies were examined. Only studies examining PBT interventions could be pooled statistically using meta-analysis. Eight &quot;good&quot; studies examined PBT, total n = 424; SOE was high for improved child behavior, standardized mean difference = -0.68 (95% confidence interval: -0.88 to -0.47), with minimal heterogeneity among studies. Only 1 good study evaluated methylphenidate, total n = 114; therefore, SOE for methylphenidate was low. Combined home and school/day care interventions showed inconsistent results. The literature reported adverse effects for methylphenidate but not for PBT. 

**CONCLUSIONS: **
With more studies consistently documenting effectiveness, PBT interventions have greater evidence of effectiveness than methylphenidate for treatment of preschoolers at risk for ADHD.
AD  - Charach,Alice. Department of Psychiatry, The Hospital for Sick Children, Toronto, Ontario, Canada. alice.charach@sickkids.ca
AN  - 23545375
AU  - Charach,
AU  - A.
AU  - Carson,
AU  - P.
AU  - Fox,
AU  - S.
AU  - Ali,
AU  - M.
AU  - U.
AU  - Beckett,
AU  - J.
AU  - Lim,
AU  - C.
AU  - G.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2012-0974
DP  - Ovid Technologies
J2  - Pediatrics
KW  - *Attention Deficit Disorder with Hyperactivity/di [Diagnosis] *Attention Deficit Disorder with Hyperactivity/th [Therapy] *Behavior Therapy/mt [Methods] Central Nervous System Stimulants/tu [Therapeutic Use] Child Behavior Child, Preschool Combined Moda
L1  - internal-pdf://0788181775/Charach-2013-Interventions for preschool child.pdf
LA  - English
M3  - Comparative Study Research Support, U.S. Gov&#039;t, P.H.S. Review
N1  - Charach, Alice Carson, Patricia Fox, Steven Ali, Muhammad Usman Beckett, Julianna Lim, Choon Guan Comment in: Praxis (Bern 1994). 2013 Jul 3;102(14):877-8; PMID: 23823688 MME2202 290-02-0020 (United States PHS HHS)
PY  - 2013
SP  - e1584-604
T2  - Pediatrics
TI  - Interventions for preschool children at high risk for ADHD: a comparative effectiveness review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23545375 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23545375&amp;id=doi:10.1542%2Fpeds.2012-0974&amp;issn=0031-4005&amp;isbn=&amp;volume=131&amp;issue=5&amp;spage=e1584&amp;pages=e1584-604&amp;date=2013&amp;title=Pediatrics&amp;atitle=Interventions+for+preschool+children+at+high+risk+for+ADHD%3A+a+comparative+effectiveness+review.&amp;aulast=Charach&amp;pid=%3Cauthor%3ECharach+A%3C%2Fauthor%3E%3CAN%3E23545375%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://pediatrics.aappublications.org/content/131/5/e1584.full.pdf
UR  - http://pediatrics.aappublications.org/content/pediatrics/131/5/e1584.full.pdf
VL  - 131
ER  -
TY  - JOUR
AB  - **Background: **
Worldwide, cannabis is the most prevalently used illegal drug and creates demand for prevention and treatment services that cannot be fulfilled using conventional approaches. Computer and Internet-based interventions may have the potential to meet this need. Therefore, we systematically reviewed the literature and conducted a meta-analysis on the effectiveness of this approach in reducing the frequency of cannabis use. 

**Methods: **
We systematically searched online databases (Medline, PubMed, PsychINFO, Embase) for eligible studies and conducted a meta-analysis. Studies had to use a randomized design, be delivered either via the Internet or computer and report separate outcomes for cannabis use. The principal outcome measure was the frequency of cannabis use. 

**Results: **
Data were extracted from 10 studies and the meta-analysis involved 10 comparisons with 4125 participants. The overall effect size was small but significant, g = 0.16 (95% confidence interval (CI) 0.09-0.22, P &lt; 0.001) at post-treatment. Subgroup analyses did not reveal significant subgroup differences for key factors including type of analysis (intention-to-treat, completers only), type of control (active, waitlist), age group (11-16, 17 + years), gender composition (female only, mixed), type of intervention (prevention, &#039;treatment&#039;), guided versus unguided programs, mode of delivery (Internet, computer), individual versus family dyad and venue (home, research setting). Also, no significant moderation effects were found for number of sessions and time to follow-up. Finally, there was no evidence of publication bias 

**Conclusions: **
Internet and computer interventions appear to be effective in reducing cannabis use in the short-term albeit based on data from few studies and across diverse samples. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Tait, Robert J.: Robert.Tait@curtin.edu.au Tait, Robert J.: National Drug Research Institute, Curtin University, GPO Box U1987, Perth, WAU, Australia, 6845, Robert.Tait@curtin.edu.au Tait, Robert J.: Centre for Mental Health Researcha, Australian National University, Canberra, ACT, Australia Spijkerman, Renske: Parnassia Addiction Research Centre (PARC), Brijder Addiction Treatment, Parnassia Group, The Hague, Netherlands Riper, Heleen: Department of Clinical Psychology, VU University Amsterdam, Amsterdam, Netherlands
AN  - 2013-45526-001
AU  - Tait,
AU  - R.
AU  - J.
AU  - Spijkerman,
AU  - R.
AU  - Riper,
AU  - H.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.drugalcdep.2013.05.012
DP  - Ovid Technologies
KW  - internet-based intervention, computer-based interventions, cannabis use, drug rehabilitation, efficacy *Cannabis *Drug Rehabilitation *Internet *Marijuana Usage *Online Therapy Treatment Effectiveness Evaluation Drug &amp; Alcohol Rehabilitation [3383] Huma
LA  - English
M3  - Meta Analysis; Treatment Outcome/Clinical Trial
PY  - 2013
SP  - 295-304
T2  - Drug and Alcohol Dependence
TI  - Internet and computer based interventions for cannabis use: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-45526-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.drugalcdep.2013.05.012&amp;issn=0376-8716&amp;isbn=&amp;volume=133&amp;issue=2&amp;spage=295&amp;pages=295-304&amp;date=2013&amp;title=Drug+and+Alcohol+Dependence&amp;atitle=Internet+and+computer+based+interventions+for+cannabis+use%3A+A+meta-analysis.&amp;aulast=Tait&amp;pid=%3Cauthor%3ETait%2C+Robert+J%3C%2Fauthor%3E%3CAN%3E2013-45526-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0376871613001877/1-s2.0-S0376871613001877-main.pdf?_tid=073ccbda-18da-11e5-bea7-00000aacb35d&amp;acdnat=1434976220_5a71092bfe09fc0685941bde69e5fd79
VL  - 133
ER  -
TY  - JOUR
AB  - Children&#039;s health policy has highlighted the need to develop self-care programmes. However, there is a lack of evidence on which to base the development of such programmes. This paper reviews the published research on the effectiveness of self-care support interventions for children and young people with asthma, cystic fibrosis and diabetes. 

A systematic search was conducted of a range of electronic databases, supplemented by searching the reference lists of retrieved papers and published reviews. Retrieved studies were assessed against quality and eligibility criteria by two independent reviewers. 

The results were narratively synthesized to examine the effectiveness of self-care support interventions on health status, psycho-social well-being, condition-related knowledge, health service use and participant satisfaction. The search strategy identified 4261 papers which were screened against the review inclusion criteria. 

A total of 194 papers were assessed as being potentially eligible for inclusion with 15 papers being judged as adequate to include in the review. There is strong evidence of the effectiveness of interventions that target children/young people; use e-health or group-based methods; that are delivered in community settings. 

There is no evidence that interventions that focus on parents alone or are delivered only in hospital settings are effective. 

While there is some evidence to inform the development of self-care support programmes, there is a need for well-designed trials of interventions that are feasible to transfer into real-life settings and which involve parents and children in their development.
AD  - [Kirk, S.; Callery, P.; Gellatly, J.; Milnes, L.; Pryjmachuk, S.] Univ Manchester, Sch Nursing Midwifery &amp; Social Work, Manchester M13 9PL, Lancs, England. [Beatty, S.] Univ Manchester, Sch Community Based Med, Manchester M13 9PL, Lancs, England. Kirk, S (reprint author), Univ Manchester, Sch Nursing Midwifery &amp; Social Work, Jean McFarlane Bldg,Oxford Rd, Manchester M13 9PL, Lancs, England. sue.kirk@manchester.ac.uk
AN  - WOS:000317423200001
AU  - Kirk,
AU  - S.
AU  - Beatty,
AU  - S.
AU  - Callery,
AU  - P.
AU  - Gellatly,
AU  - J.
AU  - Milnes,
AU  - L.
AU  - Pryjmachuk,
AU  - S.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1365-2214.2012.01395.x
J2  - Child Care Health Dev.
KW  - adolescents children chronic illness self care systematic review RANDOMIZED CONTROLLED-TRIAL INNER-CITY CHILDREN IMPROVING ASTHMA OUTCOMES CYSTIC-FIBROSIS MANAGEMENT EDUCATION CHILDHOOD ASTHMA ADOLESCENTS LIFE Psychology, Developmental Pediatrics
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 123WU Times Cited: 3 Cited Reference Count: 59 Kirk, S. Beatty, S. Callery, P. Gellatly, J. Milnes, L. Pryjmachuk, S. bolzani, berliete/F-8406-2013; Pryjmachuk, Steven/D-6337-2011; Gellatly, Judith/O-4287-2014 Pryjmachuk, Steven/0000-0002-6976-1727; Gellatly, Judith/0000-0002-5134-5581 National Institute for Health Research Service Delivery and Organisation programme This project was funded by the National Institute for Health Research Service Delivery and Organisation programme. The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the National Institute for Health Research Service Delivery and Organisation programme or the Department of Health. 3 WILEY-BLACKWELL HOBOKEN CHILD CARE HLTH DEV
PY  - 2013
SP  - 305-324
T2  - Child Care Health and Development
TI  - The effectiveness of self-care support interventions for children and young people with long-term conditions: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000317423200001http://onlinelibrary.wiley.com/store/10.1111/j.1365-2214.2012.01395.x/asset/cch1395.pdf?v=1&amp;t=ib7nmbyk&amp;s=8cf1037574f2094df11cbcecb69a66bfaab1d9ce
VL  - 39
ER  -
TY  - JOUR
AB  - **PURPOSE: **
Impaired attention is reported in children following treatment for brain tumours (BT). Attention problems impact on information processing and encoding, ultimately leading to academic under-performance. Having been successfully used to manage attention-deficit/hyperactivity disorder (ADHD), stimulants such as methylphenidate (MPH) have been investigated as a beneficial treatment for survivors of childhood BT. In order to develop appropriate strategies to manage late neurocognitive effects, the results of such trials should be evaluated to identify those children most likely to benefit from stimulants. 

**DESIGN: **
An advanced search was performed across twelve electronic databases for the selection of relevant randomised controlled trials with at least one active stimulant-treated arm. Abstracts were screened for eligibility and data on study design and results were extracted. 

**RESULTS: **
Of the 5446 records identified, 11 full text articles were assessed for eligibility and seven included in qualitative synthesis. Of the seven papers there were four original trials. Short term outcomes for MPH on objective direct measures of attention and parent/teacher ratings of behaviour were favourable. Observations of side effects indicate that MPH is generally well tolerated. Heterogeneity of study design and outcome measures precluded meta-analysis. 

**CONCLUSION: **
Despite yielding only a small number of trials with limited sample size, studies investigating the use of stimulant medication in survivors of childhood BT have provided promising outcomes. Current evidence indicates males, older age when treated, and higher baseline intelligence quotient (IQ) were predictive of greater responsiveness to MPH. While encouraging, additional research using a standardised protocol of outcome measures would be beneficial in identifying those likely to benefit from stimulant use. Further, the available data have yet to establish clear evidence for the effectiveness of MPH being translated into improvements on standardised measures of academic achievement.

Copyright &copy; 2013 Elsevier Ltd. All rights reserved.
AD  - Smithson,Emilie F. Programme in Clinical Psychology, Leeds Institute of Health Sciences, Charles Thackrah Building, Clarendon Road, Leeds LS2 9LJ, UK.
AN  - 23831334
AU  - Smithson,
AU  - E.
AU  - F.
AU  - Phillips,
AU  - R.
AU  - Harvey,
AU  - D.
AU  - W.
AU  - Morrall,
AU  - M.
AU  - C.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.ejca.2013.05.023
DP  - Ovid Technologies
J2  - Eur J Cancer
KW  - Adolescent Attention/de [Drug Effects] Attention/ph [Physiology] *Brain Neoplasms/pp [Physiopathology] Brain Neoplasms/px [Psychology] *Central Nervous System Stimulants/tu [Therapeutic Use] Child *Cognition/de [Drug Effects] Cognition/ph [Physiology] F
LA  - English
M3  - Review
N1  - Smithson, Emilie F Phillips, Robert Harvey, David W Morrall, Matthew C H J Comment in: Eur J Cancer. 2014 May;50(8):1566-8; PMID: 24675286 Comment in: Eur J Cancer. 2014 May;50(8):1569-70; PMID: 24650580 S0959-8049(13)00431-0
PY  - 2013
SP  - 3029-40
T2  - European Journal of Cancer
TI  - The use of stimulant medication to improve neurocognitive and learning outcomes in children diagnosed with brain tumours: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23831334 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23831334&amp;id=doi:10.1016%2Fj.ejca.2013.05.023&amp;issn=0959-8049&amp;isbn=&amp;volume=49&amp;issue=14&amp;spage=3029&amp;pages=3029-40&amp;date=2013&amp;title=European+Journal+of+Cancer&amp;atitle=The+use+of+stimulant+medication+to+improve+neurocognitive+and+learning+outcomes+in+children+diagnosed+with+brain+tumours%3A+a+systematic+review.&amp;aulast=Smithson&amp;pid=%3Cauthor%3ESmithson+EF%3C%2Fauthor%3E%3CAN%3E23831334%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0959804913004310/1-s2.0-S0959804913004310-main.pdf?_tid=bb8ed3fc-18db-11e5-bb31-00000aacb35f&amp;acdnat=1434976952_6860494f7bc32856ee9a5219cbfaaea4
VL  - 49
ER  -
TY  - JOUR
AB  - **Background: **
A number of parenting programs, aimed at improving parenting competencies, have recently been adapted or designed with the use of online technologies. Although web-based services have been claimed to hold promise for parent support, a meta-analytic review of online parenting interventions is lacking. 

**Method:** 
A systematic review was undertaken of studies (n = 19), published between 2000 and 2010, that describe parenting programs of which the primary components were delivered online. Seven programs were adaptations of traditional, mostly evidence-based, parenting interventions, using the unique opportunities of internet technology. Twelve studies (with in total 54 outcomes, Ntot parents = 1615 and Ntot children = 740) were included in a meta-analysis. 

**Results: **
The meta-analysis showed a statistically significant medium effect across parents outcomes (ES = 0.67; se = 0.25) and child outcomes (ES = 0.42; se = 0.15). 

**Conclusions: **
The results of this review show that web-based parenting programs with new technologies offer opportunities for sharing social support, consulting professionals and training parental competencies. The meta-analytic results show that guided and self-guided online interventions can make a significant positive contribution for parents and children. The relation with other meta-analyses in the domains of parent education and web-based interventions is discussed. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - A Nieuwboer, Christa C.: c.nieuwboer@fontys.nl Nieuwboer, Christa C.: Fontys School of Pedagogical Studies, Fontys University of Applied Sciences, Mgr. Claessenstraat 4, Sittard, Netherlands, 6131 AJ, c.nieuwboer@fontys.nl Nieuwboer, Christa C.: Faculty of Social and Behavioural Sciences, University of Amsterdam, Amsterdam, Netherlands Fukkink, Ruben G.: Faculty of Social and Behavioural Sciences, University of Amsterdam, Amsterdam, Netherlands Hermanns, Jo M. A.: Faculty of Social and Behavioural Sciences, University of Amsterdam, Amsterdam, Netherlands
AN  - 2013-37092-006
AU  - Nieuwboer,
AU  - C.
AU  - C.
AU  - Fukkink,
AU  - R.
AU  - G.
AU  - Hermanns,
AU  - J.
AU  - M.
AU  - A.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2013.08.008
DP  - Ovid Technologies
KW  - online parenting programs, parenting, interventions, social support *Internet *Parent Training *Parenting Intervention Social Support Childrearing &amp; Child Care [2956] Human Adulthood (18 yrs &amp; older)
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2013
SP  - 1823-1829
T2  - Children and Youth Services Review
TI  - Online programs as tools to improve parenting: A meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-37092-006 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2013.08.008&amp;issn=0190-7409&amp;isbn=&amp;volume=35&amp;issue=11&amp;spage=1823&amp;pages=1823-1829&amp;date=2013&amp;title=Children+and+Youth+Services+Review&amp;atitle=Online+programs+as+tools+to+improve+parenting%3A+A+meta-analytic+review.&amp;aulast=Nieuwboer&amp;pid=%3Cauthor%3ENieuwboer%2C+Christa+C%3C%2Fauthor%3E%3CAN%3E2013-37092-006%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0190740913002648/1-s2.0-S0190740913002648-main.pdf?_tid=ffc6fec8-18cc-11e5-bb2f-00000aacb35f&amp;acdnat=1434970624_6fd3b60921a1b58b22cc65278bf671b2
VL  - 35
ER  -
TY  - JOUR
AB  - This study reports on a meta-analysis of moral reconation therapy (MRT). Recipients of MRT included adult and juvenile offenders who were in custody or in the community, typically on parole or probation. 

The study considered criminal offending subsequent to treatment as the outcome variable. The overall effect size measured by the correlation across 33 studies and 30,259 offenders was significant (r = .16), indicating that MRT had a small but important effect on recidivism. 

Moderator analyses were conducted to detect the possible factors affecting the relationship between MRT and recidivism. Moderators included setting, age, gender, research design, sample size, type of recidivism, follow-up period, publisher, and year of publication. Moderator analysis demonstrated that MRT was more successful with adult than juvenile offenders in institutional settings as opposed to the community, and where researchers in the primary studies used randomization to allocate participants to either a treatment or control condition. 

The treatment effect size was greater when the type of recidivism used was rearrest rather than rearrest followed by conviction or reincarceration. The benefits of MRT were strongest with a relatively short follow-up period. MRT was more successful for relatively small samples and for large samples rather than medium-sized samples. 

The effect size was smaller for studies published by the owners of MRT than by other independent studies. The effect size was also smaller for studies published after 1999.
AD  - Ferguson,L Myles. Department of Psychology, University of Saskatchewan, 9 Campus Drive, Saskatoon, SK S7N 5A5, Canada. myles05@sasktel.net
AN  - 22744908
AU  - Ferguson,
AU  - L.
AU  - M.
AU  - Wormith,
AU  - J.
AU  - S.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0306624X12447771
DP  - Ovid Technologies
J2  - Int J Offender Ther Comp Criminol
KW  - Adolescent Adult *Cognitive Therapy/mt [Methods] *Crime/pc [Prevention &amp; Control] *Crime/px [Psychology] Female Humans Juvenile Delinquency/pc [Prevention &amp; Control] Juvenile Delinquency/px [Psychology] Juvenile Delinquency/rh [Rehabilitation] Male *Mor
LA  - English
M3  - Meta-Analysis
N1  - Ferguson, L Myles Wormith, J Stephen
PY  - 2013
SP  - 1076-106
T2  - International Journal of Offender Therapy &amp; Comparative Criminology
TI  - A meta-analysis of moral reconation therapy
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22744908 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22744908&amp;id=doi:10.1177%2F0306624X12447771&amp;issn=0306-624X&amp;isbn=&amp;volume=57&amp;issue=9&amp;spage=1076&amp;pages=1076-106&amp;date=2013&amp;title=International+Journal+of+Offender+Therapy+%26+Comparative+Criminology&amp;atitle=A+meta-analysis+of+moral+reconation+therapy.&amp;aulast=Ferguson&amp;pid=%3Cauthor%3EFerguson+LM%3C%2Fauthor%3E%3CAN%3E22744908%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ijo.sagepub.com/content/57/9/1076http://ijo.sagepub.com/content/57/9/1076.full.pdf
VL  - 57
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Overweight and obese children and adolescents face many physical and psychosocial hardships. Resistance training is a modality of exercise which allows this at-risk group to excel and therefore has the potential to positively affect not only their physical but also psychosocial health. 

**OBJECTIVE: **
To systematically review and meta-analyse the peer-reviewed literature to determine the effect of resistance training on the strength, body composition and psychosocial status of overweight and/or obese children and/or adolescents. DATA SOURCES: Relevant databases (MEDLINE, Embase, Scopus, Web of Science, SPORTDiscus, CINAHL, PsycINFO, Cochrane library, ProQuest) were searched up to and including 30 January 2013. 

**STUDY SELECTION: **
Included studies (n = 40, from the 2,247 identified) were randomised controlled trials (RCTs), non-randomised controlled trials (NRCTs) and uncontrolled trials (UCTs) which had run an exercise intervention, with a resistance training component, for overweight and/or obese children and/or adolescents, and which had examined the effect of resistance training on either strength, body composition or psychosocial outcomes. 

**STUDY APPRAISAL AND SYNTHESIS METHODS: **
Studies were initially critically appraised for risk of bias by the lead author, following which both co-authors critically appraised five randomly selected studies to assess reliability. 

**RESULTS:**
Randomised controlled trials and NRCTs were analysed separately from UCTs. To determine the overall intervention effect for each outcome variable for each study design group, standardised mean differences were calculated with each individual study/data set weighted by the inverse of the pooled variance. The overall intervention effect reported for RCTs and NRCTs was relative to the control group whereas the effect reported for UCTs shows an overall post-intervention effect. Subgroup analyses, which determined whether the overall intervention effect was influenced by intervention type, training volume, age, sex, risk of bias or study design (for RCT/NRCT group only), were run using the same summary measure. Typically, resistance training had very small to small effects on body composition and moderate to large effects on strength in favour of the intervention. However, the magnitude and direction of the effect of resistance training on psychological outcomes are still unclear given the limited number of studies which looked at psychosocial outcomes and the inconclusive results shown by this review. Uncontrolled trials typically showed larger intervention effects than RCTs and NRCTs; however, these results may be greatly influenced by maturational changes rather than the intervention itself. 

**LIMITATIONS: **
The included studies employed a number of different exercise intervention types (e.g. resistance training, resistance plus aerobic training etc.) that ranged from 6 to 52 weeks in duration. Studies also employed a number of different methodologies to assess similar outcome measures (e.g. dual energy X-ray absorptiometry versus skinfolds to assess body composition; one-repetition maximum testing versus hand grip strength to assess strength). However, by completing subgroup analyses and using a standardised summary measure these limitations have been accounted for. 

**CONCLUSION: **
While the effect of resistance training on the body composition and strength of overweight and obese children and adolescents is clear, given the paucity of conclusive data more studies are needed to fully understand the effect of resistance training on the psychosocial status of this population.
AD  - Schranz,Natasha. Health and Use of Time (HUT) Group, Sansom Institute for Health Research, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia. natasha.schranz@mymail.unisa.edu.au
AN  - 23729196
AU  - Schranz,
AU  - N.
AU  - Tomkinson,
AU  - G.
AU  - Olds,
AU  - T.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s40279-013-0062-9
DP  - Ovid Technologies
J2  - Sports Med
KW  - Adolescent *Body Composition Child Humans *Muscle Strength *Muscle, Skeletal/ph [Physiology] *Obesity/pp [Physiopathology] *Obesity/px [Psychology] Overweight/pp [Physiopathology] Overweight/px [Psychology] Randomized Controlled Trials as Topic *Resista
LA  - English
M3  - Meta-Analysis Review
N1  - Schranz, Natasha Tomkinson, Grant Olds, Tim
PY  - 2013
SP  - 893-907
T2  - Sports Medicine
TI  - What is the effect of resistance training on the strength, body composition and psychosocial status of overweight and obese children and adolescents? A Systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23729196 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23729196&amp;id=doi:10.1007%2Fs40279-013-0062-9&amp;issn=0112-1642&amp;isbn=&amp;volume=43&amp;issue=9&amp;spage=893&amp;pages=893-907&amp;date=2013&amp;title=Sports+Medicine&amp;atitle=What+is+the+effect+of+resistance+training+on+the+strength%2C+body+composition+and+psychosocial+status+of+overweight+and+obese+children+and+adolescents%3F+A+Systematic+review+and+meta-analysis.&amp;aulast=Schranz&amp;pid=%3Cauthor%3ESchranz+N%3C%2Fauthor%3E%3CAN%3E23729196%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://media.proquest.com/media/pq/classic/doc/3143245941/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Schranz%2C+Natasha%3BTomkinson%2C+Grant%3BOlds%2C+Tim&amp;cit%3Atitle=What+is+the+Effect+of+Resistance+Training+on+the+Strength%2C+Body+...&amp;cit%3Apub=Sports+Medicine&amp;cit%3Avol=43&amp;cit%3Aiss=9&amp;cit%3Apg=893&amp;cit%3Adate=Sep+2013&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMjA2MzQ0MzIxNDoyODMyNzMSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFMzIxOTcyCjE0NjI5OTU1NzE6DURvY3VtZW50SW1hZ2VCATBSBk9ubGluZVoCRlRiA1BGVGoKMjAxMy8wOS8wMXIKMjAxMy8wOS8zMHoAggEpUC0xMDAwMjczLTMxMDc1LUNVU1RPTUVSLTEwMDAwMTU3LTExMTUxMTKSAQZPbmxpbmXKAQdFbmROb3Rl0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCKE9TOkVNUy1QZGZEb2NWaWV3QmFzZS1nZXRNZWRpYVVybEZvckl0ZW3KAiNHZW5lcmFsIEluZm9ybWF0aW9ufEFydGljbGV8RmVhdHVyZdICAVniAgFO8gIA&amp;_s=z%2F2IUsEq93mzO4FUBFnF5D7c780%3D
UR  - https://link.springer.com/article/10.1007%2Fs40279-013-0062-9
VL  - 43
ER  -
TY  - JOUR
AB  - Second-generation antipsychotics (SGAs) induce frequent adverse effects in children and adolescents with each compound appearing to have a specific adverse effect profile. 

Aripiprazole and risperidone are FDA-approved medications for behavioral disturbances associated with autism and/or intellectual disabilities (ID) in children and adolescents. Using Bayesian meta-analysis of all relevant studies (N = 8; 18 arms; 782 patients), we aimed to calculate odds ratios (OR) or mean average effects to assess efficacy, weight gain, metabolic changes, sedation, and extra-pyramidal syndrome (EPS) of the two compounds. 

Reporting was incomplete to assess metabolic changes. Compared to placebo, significant treatment-related increases were observed for: CGI response with aripiprazole (OR = 6.09, 95% credible interval [2.3-12.63]) and risperidone (12.8 [5.57-27.33]); weight gain with aripiprazole (OR = 6.28 [1.64-17.12]) and risperidone (7.76 [1.88-25.2]); EPS with risperidone (OR = 3.72 [1.73-7.22]); and somnolence/sedation with aripiprazole (OR = 25.76 [1.29-112.3]) and risperidone (9.63 [3.52-22.79]). 

There were no significant differences between active compounds. We conclude that short term efficacy of risperidone and aripiprazole are similar for behavioral disturbances associated with autism and/or ID, and that secondary effects are frequent. 

More research should be conducted on metabolic changes as current literature is lacking compared to other indications in youths. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - Cohen, David: david.cohen@psl.aphp.fr Cohen, David: Department of Child and Adolescent Psychiatry, Universite Pierre et Marie Curie, Hopital de la Pitie-Salp triere, AP-HP, 47 bld de l&#039;Hopital, Paris, France, 75013, david.cohen@psl.aphp.fr Cohen, David: Department of Child and Adolescent Psychiatry, Universite Pierre et Marie Curie, GH Pitie Salpetriere, Paris, France Raffin, Marie: Department of Child and Adolescent Psychiatry, Universite Pierre et Marie Curie, GH Pitie Salpetriere, Paris, France Canitano, Roberto: Department of Child NeuroPsychiatry, University of Sienna, Sienna, Italy Bodeau, Nicolas: Department of Child and Adolescent Psychiatry, Universite Pierre et Marie Curie, GH Pitie Salpetriere, Paris, France Bonnot, Olivier: Department of Child and Adolescent Psychiatry, Universite Pierre et Marie Curie, GH Pitie Salpetriere, Paris, France Perisse, Didier: Department of Child and Adolescent Psychiatry, Universite Pierre et Marie Curie, GH Pitie Salpetriere, Paris, France Consoli, Angele: Department of Child and Adolescent Psychiatry, Universite Pierre et Marie Curie, GH Pitie Salpetriere, Paris, France Laurent, Claudine: Department of Child and Adolescent Psychiatry, Universite Pierre et Marie Curie, GH Pitie Salpetriere, Paris, France
AN  - 2012-29769-019
AU  - Cohen,
AU  - D.
AU  - Raffin,
AU  - M.
AU  - Canitano,
AU  - R.
AU  - Bodeau,
AU  - N.
AU  - Bonnot,
AU  - O.
AU  - Perisse,
AU  - D.
AU  - Consoli,
AU  - A.
AU  - Laurent,
AU  - C.
DA  - Jan-Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.rasd.2012.08.001
DP  - Ovid Technologies
KW  - risperidone, aripiprazole, age differences, autism, intellectual disabilities, mental retardation, drug efficacy, secondary effects *Autism *Drug Therapy *Risperidone *Side Effects (Drug) *Aripiprazole Age Differences Intellectual Development Disorder D
LA  - English
M3  - Meta Analysis
PY  - 2013
SP  - 167-175
T2  - Research in Autism Spectrum Disorders
TI  - Risperidone or aripiprazole in children and adolescents with Autism and/or intellectual disability: A Bayesian meta-analysis of efficacy and secondary effects
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2012-29769-019 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.rasd.2012.08.001&amp;issn=1750-9467&amp;isbn=&amp;volume=7&amp;issue=1&amp;spage=167&amp;pages=167-175&amp;date=2013&amp;title=Research+in+Autism+Spectrum+Disorders&amp;atitle=Risperidone+or+aripiprazole+in+children+and+adolescents+with+Autism+and%2For+intellectual+disability%3A+A+Bayesian+meta-analysis+of+efficacy+and+secondary+effects.&amp;aulast=Cohen&amp;pid=%3Cauthor%3ECohen%2C+David%3C%2Fauthor%3E%3CAN%3E2012-29769-019%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1750946712000943/1-s2.0-S1750946712000943-main.pdf?_tid=7eb0bdf4-167b-11e5-bbda-00000aacb35e&amp;acdnat=1434715716_6714fa379fee482ccc3549de58ffb8a8
VL  - 7
ER  -
TY  - JOUR
AB  - The aim of this meta-analytic study, including 22 studies and 5764 participants, was to examine the effects of aftercare programs on recidivism in juvenile and young adult offenders released from correctional institutions. 

The studies had to be (quasi-)experimental, with the control group receiving &#039;care as usual&#039; or no treatment. Recidivism was measured by re-arrests and/or reconvictions and was based on official reports. 

Although the overall effect size for aftercare programs was generally small (d = .12), moderator analyses indicated more substantial effects and showed that aftercare is most effective if it is well-implemented and consists of individual instead of group treatment, and if it is aimed at older and high-risk youth. 

Whereas the treatment duration and moment of starting the aftercare program were not related to the program&#039;s effectiveness, more intensive aftercare programs were associated with lower recidivism rates. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - M James, Chrissy: c.james@uva.nl James, Chrissy: Faculty of Social and Behavioral Sciences, Forensic Child &amp; Youth Care Sciences, University of Amsterdam, Nieuwe Prinsengracht 130, Amsterdam, Netherlands, 1018 VZ, c.james@uva.nl James, Chrissy: Forensic Child &amp; Youth Care Sciences, University of Amsterdam (UvA), Amsterdam, Netherlands Stams, Geert Jan J. M.: Forensic Child &amp; Youth Care Sciences, University of Amsterdam (UvA), Amsterdam, Netherlands Asscher, Jessica J.: Forensic Child &amp; Youth Care Sciences, University of Amsterdam (UvA), Amsterdam, Netherlands De Roo, Anne Katrien: Forensic Child &amp; Youth Care Sciences, University of Amsterdam (UvA), Amsterdam, Netherlands van der Laan, Peter H.: Netherlands Institute for the Study of Crime and Law Enforcement (NSCR), Amsterdam, Netherlands
AN  - 2013-03817-006
AU  - James,
AU  - C.
AU  - Stams,
AU  - G.
AU  - J.
AU  - Asscher,
AU  - J.
AU  - De
AU  - Roo,
AU  - A.
AU  - K.
AU  - van
AU  - der
AU  - Laan,
AU  - P.
AU  - H.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2012.10.013
DP  - Ovid Technologies
KW  - aftercare programs, recidivism, offenders, age differences, correctional institutions *Correctional Institutions *Criminals *Health Care Services *Recidivism *Social Programs Age Differences Juvenile Delinquency Health &amp; Mental Health Services [3370] Hu
LA  - English
M3  - Meta Analysis
PY  - 2013
SP  - 263-274
T2  - Clinical Psychology Review
TI  - Aftercare programs for reducing recidivism among juvenile and young adult offenders: A meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-03817-006 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.cpr.2012.10.013&amp;issn=0272-7358&amp;isbn=&amp;volume=33&amp;issue=2&amp;spage=263&amp;pages=263-274&amp;date=2013&amp;title=Clinical+Psychology+Review&amp;atitle=Aftercare+programs+for+reducing+recidivism+among+juvenile+and+young+adult+offenders%3A+A+meta-analytic+review.&amp;aulast=James&amp;pid=%3Cauthor%3EJames%2C+Chrissy%3C%2Fauthor%3E%3CAN%3E2013-03817-006%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735812001651/1-s2.0-S0272735812001651-main.pdf?_tid=214ac3b8-1972-11e5-8ff6-00000aab0f27&amp;acdnat=1435041548_885564a7a84ef5f256cb453c2214598c
VL  - 33
ER  -
TY  - JOUR
AB  - **Background:**
Children involved in the child welfare system (CWS) have a greater need for mental health treatment relative to children in the general population. However, the research on mental health treatment for children in the CWS is sparse with only one known previous review of mental health services with children in the CWS. 

**Objective:**
This review reports on an evaluation of the literature examining mental health interventions for children within the CWS. 

**Methods: **
The Grades of Recommendation Assessment, Development and Evaluation (GRADE) process was used as the basis of the evaluation. 

**Results: **
The results reflect that, while the overall quality of research in this area is low and findings are, at times, inconsistent, detailed, manualized interventions using multiple treatment components that focus on family, child, and school factors showed the most promise in regards to child mental health outcomes and placement stability. These interventions not only report the best quality outcomes for children and families, but they were also most highly recommended within the GRADE analysis. 

**Conclusions: **
These findings emphasize the importance of comprehensive intervention efforts that involve the family and community, as well as the child. The inconsistent positive outcomes may be partially explained by the lack of trauma-informed practices incorporated into treatment for these often traumatized children. Recommendations for research in regards to mental health interventions for children in the CWS are discussed. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - Stewart, Shannon L.: shannon.stewart@ontario.ca; Leschied, Alan: leschied@uwo.ca; den Dunnen, Wendy: wdend082@uottawa.ca; Zalmanowitz, Sharla: sharla.zalmanowitz@gmail.com; Baiden, Philip: philip.baiden@ontario.ca Leschied, Alan: Faculty of Education, The University of Western Ontario, 1137 Western Road, London, ON, Canada, ON N6G 1G7, leschied@uwo.ca Stewart, Shannon L.: Child and Parent Resource Institute, Western University, London, ON, Canada Leschied, Alan: Faculty of Education, The University of Western Ontario, London, ON, Canada den Dunnen, Wendy: University of Ottawa, Ottawa, Canada Zalmanowitz, Sharla: Calgary Clinic, Calgary, Canada Baiden, Philip: Child and Parent Resource Institute, London, ON, Canada
AN  - 2013-10048-004
AU  - Stewart,
AU  - S.
AU  - L.
AU  - Leschied,
AU  - A.
AU  - den
AU  - Dunnen,
AU  - W.
AU  - Zalmanowitz,,
AU  - S.
AU  - Baiden,
AU  - P.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10566-012-9192-8
DP  - Ovid Technologies
KW  - mental health disorders, treatment, child welfare system *Child Welfare *Mental Disorders *Mental Health Treatment Community &amp; Social Services [3373] Human Male Female Childhood (birth-12 yrs) Preschool Age (2-5 yrs) School Age (6-12 yrs) Canada
LA  - English
M3  - Literature Review
PY  - 2013
SP  - 131-154
T2  - Child and Youth Care Forum
TI  - Treating mental health disorders for children in child welfare care: Evaluating the outcome literature
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc10&amp;AN=2013-10048-004 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10566-012-9192-8&amp;issn=1053-1890&amp;isbn=&amp;volume=42&amp;issue=2&amp;spage=131&amp;pages=131-154&amp;date=2013&amp;title=Child+%26+Youth+Care+Forum&amp;atitle=Treating+mental+health+disorders+for+children+in+child+welfare+care%3A+Evaluating+the+outcome+literature.&amp;aulast=Stewart&amp;pid=%3Cauthor%3EStewart%2C+Shannon+L%3C%2Fauthor%3E%3CAN%3E2013-10048-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10566-012-9192-8http://download.springer.com/static/pdf/477/art%253A10.1007%252Fs10566-012-9192-8.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10566-012-9192-8&amp;token2=exp=1435234706~acl=%2Fstatic%2Fpdf%2F477%2Fart%25253A10.1007%25252Fs10566-012-9192-8.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10566-012-9192-8*~hmac=4de9f2e2798aa55d4ad6459edcfb4808254a26aa049cf7c22c0447518d37598d
VL  - 42
ER  -
TY  - JOUR
AB  - This article reviews outcomes of psychodynamic psychotherapy (PP) for children and adolescents reported in articles identified by a comprehensive review of the literature on treatment evaluations of psychological and medical interventions for mental disorders in pediatric populations. 

The review identified 48 reports based on 33 studies. While there is evidence of substantial clinical gains associated with PP, in almost all the studies, when contrasted with family-based interventions, PP fares no better and appears to produce outcomes with some delay relative to family-based therapies. 

Further rigorous evaluations are needed, but evidence to date suggests that the context in which PP is delivered should be extended from the traditional context of individual therapy and parents should be included in the treatment of children.

Copyright &copy; 2013 Elsevier Inc. All rights reserved.
AD  - Palmer,Rose. Research Department of Clinical Educational and Health Psychology, University College London, London, UK.
AN  - 23538010
AU  - Palmer,
AU  - R.
AU  - Nascimento,
AU  - L.
AU  - N.
AU  - Fonagy,
AU  - P.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.chc.2012.12.001
DP  - Ovid Technologies
J2  - Child Adolesc Psychiatr Clin N Am
KW  - Adolescent Child Humans *Mental Disorders/th [Therapy] *Psychotherapy/mt [Methods] Randomized Controlled Trials as Topic Treatment Outcome
LA  - English
M3  - Review
N1  - Palmer, Rose Nascimento, Leonardo Niro Fonagy, Peter S1056-4993(12)00122-8
PY  - 2013
SP  - 149-214
T2  - Child &amp; Adolescent Psychiatric Clinics of North America
TI  - The state of the evidence base for psychodynamic psychotherapy for children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23538010 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23538010&amp;id=doi:10.1016%2Fj.chc.2012.12.001&amp;issn=1056-4993&amp;isbn=&amp;volume=22&amp;issue=2&amp;spage=149&amp;pages=149-214&amp;date=2013&amp;title=Child+%26+Adolescent+Psychiatric+Clinics+of+North+America&amp;atitle=The+state+of+the+evidence+base+for+psychodynamic+psychotherapy+for+children+and+adolescents.&amp;aulast=Palmer&amp;pid=%3Cauthor%3EPalmer+R%3C%2Fauthor%3E%3CAN%3E23538010%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1056499312001228/1-s2.0-S1056499312001228-main.pdf?_tid=6d6b8660-18b9-11e5-a6fe-00000aacb35d&amp;acdnat=1434962218_bd59a0cd5d3c86e8adc993adf3cba8cf
VL  - 22
ER  -
TY  - JOUR
AB  - **Background:** 
Fibromyalgia (FM) is a clinically well‐defined chronic condition of unknown aetiology characterized by chronic widespread pain that often co‐exists with sleep disturbances, cognitive dysfunction and fatigue. Patients often report high disability levels and negative mood. Psychotherapies focus on reducing key symptoms, improving daily functioning, mood and sense of personal control over pain.

**Objectives**
To assess the benefits and harms of cognitive behavioural therapies (CBTs) for treating FM at end of treatment and at long‐term (at least six months) follow‐up.

**Search methods**
We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2013, Issue 8), MEDLINE (1966 to 28 August 2013), PsycINFO (1966 to 28 August 2013) and SCOPUS (1980 to 28 August 2013). We searched http://www.clinicaltrials.gov (web site of the US National Institutes of Health) and the World Health Organization Clinical Trials Registry Platform (ICTRP) (http://www.who.int/ictrp/en/) for ongoing trials (last search 28 August,2013), and the reference lists of reviewed articles.

**Selection criteria**
We selected randomised controlled trials of CBTs with children, adolescents and adults diagnosed with FM.

**Data collection and analysis**
The data of all included studies were extracted and the risks of bias of the studies were assessed independently by two review authors. Discrepancies were resolved by discussion.

**Main results**
Twenty‐three studies with 24 study arms with CBTs were included. A total of 2031 patients were included; 1073 patients in CBT groups and 958 patients in control groups. Only two studies were without any risk of bias. The GRADE quality of evidence of the studies was low. CBTs were superior to controls in reducing pain at end of treatment by 0.5 points on a scale of 0 to 10 (standardised mean difference (SMD) ‐ 0.29; 95% confidence interval (CI) ‐0.49 to ‐0.17) and by 0.6 points at long‐term follow‐up (median 6 months) (SMD ‐0.40; 95% CI ‐0.62 to ‐0.17); in reducing negative mood at end of treatment by 0.7 points on a scale of 0 to 10 (SMD ‐ 0.33; 95% CI ‐0.49 to ‐0.17) and by 1.3 points at long‐term follow‐up (median 6 months) (SMD ‐0.43; 95% CI ‐0.75 to ‐0.11); and in reducing disability at end of treatment by 0.7 points on a scale of 0 to 10 (SMD ‐ 0.30; 95% CI ‐0.51 to ‐0.08) and at long‐term follow‐up (median 6 months) by 1.2 points (SMD ‐0.52; 95% CI ‐0.86 to ‐0.18). There was no statistically significant difference in dropout rates for any reasons between CBTs and controls (risk ratio (RR) 0.94; 95% CI 0.65 to 1.35).

**Authors&#039; conclusions**
CBTs provided a small incremental benefit over control interventions in reducing pain, negative mood and disability at the end of treatment and at long‐term follow‐up. The dropout rates due to any reason did not differ between CBTs and controls.
AN  - CD009796
AU  - Bernardy,
AU  - K.
AU  - Klose,
AU  - P.
AU  - Busch,
AU  - A.
AU  - J.
AU  - Choy,
AU  - E.
AU  - H.
AU  - H&auml;user,
AU  - W.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009796.pub2
KW  - Cognitive Therapy
KW  - Fibromyalgia [psychology] [therapy]
KW  - Negativism
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Muskel
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive behavioural therapies for fibromyalgia
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009796.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009796.pub2/asset/CD009796.pdf?v=1&amp;t=iw7j3f4e&amp;s=7bdcfbf9cc945ca22f497c438cc08193a672bf6d
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Cognitive therapies are intended to improve basic cognitive functions, whatever the cause of the deficiency may be. Children and adolescents with various cognitive deficits are treated with behavioral therapeutic and computer-supported training programs. We here report the first meta-analysis of the efficacy of such programs. 

**METHODS: **
We systematically searched the Medline, Embase, PsycINFO, PSYNDEX, and ERIC databases to find pertinent publications for a meta-analysis of cognitive training programs that are used in children and adolescents to improve attention, memory, and executive performance (primary goals) as well as behavior/psychopathology, intelligence, and school performance (secondary goals). The mean differences between the treatment and control groups are given here as standard deviation (SD) scores.

**RESULTS: **
1661 potentially relevant publications were found, including 22 studies that were considered in the meta-analysis, 17 of which were randomized controlled trials. The target variables were measured with more than 90 different testing techniques. The overall effects of cognitive training on attention (SD 0.18, 95% CI -0.11-0.47) and executive function (SD 0.17, 95% CI -0.12-0.46) were consistently small. A relatively strong effect was found on memory performance (0.65 SD, 95% [-0.12-1.42), albeit with marked heterogeneity (I (2)= 82%) owing to two studies. The largest effect was found in the area of behavior and psychopathology (SD 0.58, 95% CI 0.31-0.85), but this last figure is derived mainly from studies that lacked an active control group. 

**CONCLUSION: **
Cognitive therapies for children and adolescents have generally favorable, but probably nonspecific effects on behavior. On the other hand, the specific effects, however, were weak overall. Therapeutic benefit has been demonstrated only for certain individual types of therapy for specific indications.
AD  - Karch,Dieter. Clinic of Pediatric Neurology and Social Pediatrics, Children Center Maulbronn.
AN  - 24163706
AU  - Karch,
AU  - D.
AU  - Albers,
AU  - L.
AU  - Renner,
AU  - G.
AU  - Lichtenauer,
AU  - N.
AU  - von
AU  - Kries,
AU  - R.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3238/arztebl.2013.0643
DP  - Ovid Technologies
J2  - Dtsch
KW  - Adolescent Age Distribution Child Child, Preschool *Cognition Disorders/ep [Epidemiology] Cognition Disorders/px [Psychology] *Cognition Disorders/rh [Rehabilitation] *Cognitive Therapy/sn [Statistics &amp; Numerical Data] Comorbidity Female Humans Male *Me
L1  - internal-pdf://4153029409/Karch-2013-The efficacy of cognitive training.pdf
LA  - English
M3  - Meta-Analysis
N1  - Karch, Dieter Albers, Lucia Renner, Gerolf Lichtenauer, Norbert von Kries, Rudiger Comment in: Dtsch Arztebl Int. 2014 Feb 7;111(6):99; PMID: 24622607 Comment in: Dtsch Arztebl Int. 2014 Feb 7;111(6):99; PMID: 24622606
PY  - 2013
SP  - 643-52
T2  - Deutsches Arzteblatt International
TI  - The efficacy of cognitive training programs in children and adolescents: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=24163706 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24163706&amp;id=doi:10.3238%2Farztebl.2013.0643&amp;issn=1866-0452&amp;isbn=&amp;volume=110&amp;issue=39&amp;spage=643&amp;pages=643-52&amp;date=2013&amp;title=Deutsches+Arzteblatt+International&amp;atitle=The+efficacy+of+cognitive+training+programs+in+children+and+adolescents%3A+a+meta-analysis.&amp;aulast=Karch&amp;pid=%3Cauthor%3EKarch+D%3C%2Fauthor%3E%3CAN%3E24163706%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804756/pdf/Dtsch_Arztebl_Int-110-0643.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804756/pdf/Dtsch_Arztebl_Int-110-0643.pdf
VL  - 110
ER  -
TY  - JOUR
AB  - This is a systematic review of evidence-based treatments for children exposed to childhood maltreatment. Because exposure to childhood maltreatment has been associated with a broad range of trauma-related psychopathology (e.g., PTSD, anxiety, suicidal ideation, substance abuse) and with aggressive and violent behavior, this review describes psychotherapeutic treatments which focus on former broad range of psychopathological outcomes. 

A total of 26 randomized controlled clinical trials and seven non-randomized controlled clinical trials published between 2000 and 2012 satisfied the inclusionary criteria and were included. These studies dealt with various kinds of samples, from sexually abused and maltreated children in child psychiatric outpatient clinics or in foster care to traumatized incarcerated boys. 

A total of 27 studies evaluated psychotherapeutic treatments which used trauma-focused cognitive, behavioral or cognitive-behavioral techniques; only two studies evaluated trauma-specific treatments for children and adolescents with comorbid aggressive or violent behavior; and four studies evaluated psychotherapeutic treatments that predominantly focused on other mental health problems than PTSD and used non-trauma focused cognitive, behavioral or cognitive-behavioral techniques. 

The results of this review suggest that trauma-focused cognitive-behavioral therapy (TF-CBT) is the best-supported treatment for children following childhood maltreatment. However, in line with increased interest in the diagnosis of complex PTSD and given the likely relationship between childhood maltreatment and aggressive and violent behavior, the authors suggest that clinical practice should address a phase-oriented approach. This review concludes with a discussion of future research directions and limitations.
AD  - Leenarts,Laura E W. Department of Child and Adolescent Psychiatry, VU University Medical Center, De Bascule, Duivendrecht, P.O. Box 303, 1115 ZG, Amsterdam, The Netherlands. l.leenarts@debascule.com
AN  - 23266844
AU  - Leenarts,
AU  - L.
AU  - E.
AU  - Diehle,
AU  - J.
AU  - Doreleijers,
AU  - T.
AU  - A.
AU  - Jansma,
AU  - E.
AU  - P.
AU  - Lindauer,
AU  - R.
AU  - J.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-012-0367-5
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
KW  - Adolescent Child Child Abuse/px [Psychology] *Child Abuse/rh [Rehabilitation] *Evidence-Based Practice/mt [Methods] Female Humans Male *Psychotherapy/mt [Methods] Stress Disorders, Post-Traumatic/px [Psychology] *Stress Disorders, Post-Traumatic/th [The
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Leenarts, Laura E W Diehle, Julia Doreleijers, Theo A H Jansma, Elise P Lindauer, Ramon J L
PY  - 2013
SP  - 269-83
T2  - European Child &amp; Adolescent Psychiatry
TI  - Evidence-based treatments for children with trauma-related psychopathology as a result of childhood maltreatment: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23266844 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23266844&amp;id=doi:10.1007%2Fs00787-012-0367-5&amp;issn=1018-8827&amp;isbn=&amp;volume=22&amp;issue=5&amp;spage=269&amp;pages=269-83&amp;date=2013&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=Evidence-based+treatments+for+children+with+trauma-related+psychopathology+as+a+result+of+childhood+maltreatment%3A+a+systematic+review.&amp;aulast=Leenarts&amp;pid=%3Cauthor%3ELeenarts+LE%3C%2Fauthor%3E%3CAN%3E23266844%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://download.springer.com/static/pdf/868/art%253A10.1007%252Fs00787-012-0367-5.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-012-0367-5&amp;token2=exp=1434977894~acl=%2Fstatic%2Fpdf%2F868%2Fart%25253A10.1007%25252Fs00787-012-0367-5.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-012-0367-5*~hmac=ad50e28c025759c1030c80c3f66544ecb3f56892c198fb8c9787c8c67aca2afb
VL  - 22
ER  -
TY  - JOUR
AB  - **Background:** 
Nocturnal enuresis (bedwetting) is a socially disruptive and stressful condition which affects around 15% to 20% of five year olds and up to 2% of adults. Although there is a high rate of spontaneous remission, the social, emotional and psychological costs can be great. Behavioural interventions for treating bedwetting are defined as interventions that require a behaviour or action by the child which promotes night dryness and includes strategies which reward that behaviour. Behavioural interventions are further divided into:(a) simple behavioural interventions - behaviours or actions that can be achieved by the child without great effort; and(b) complex behavioural interventions - multiple behavioural interventions which require greater effort by the child and parents to achieve, including enuresis alarm therapy. This review focuses on simple behavioural interventions.Simple behavioural interventions are often used as a first attempt to improve nocturnal enuresis and include reward systems such as star charts given for dry nights, lifting or waking the children at night to urinate, retention control training to enlarge bladder capacity (bladder training) and fluid restriction. Other treatments such as medications, complementary and miscellaneous interventions such as acupuncture, complex behavioural interventions and enuresis alarm therapy are considered elsewhere.

**Objectives:** 
To determine the effects of simple behavioural interventions in children with nocturnal enuresis.The following comparisons were made: 1. simple behavioural interventions versus no active treatment; 2. any single type of simple behavioural intervention versus another behavioural method (another simple behavioural intervention, enuresis alarm therapy or complex behavioural interventions); 3. simple behavioural interventions versus drug treatment alone (including placebo drugs) or drug treatment in combination with other interventions.

**Search methods:** 
We searched the Cochrane Incontinence Group Specialised Trials Register, which contains trials identified from the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, MEDLINE in process, and handsearching of journals and conference proceedings (searched 15 December 2011). The reference lists of relevant articles were also searched.

**Selection criteria:** 
All randomised or quasi-randomised trials of simple behavioural interventions for treating nocturnal enuresis in children up to the age of 16. Studies which included children with daytime urinary incontinence or children with organic conditions were also included in this review if the focus of the study was on nocturnal enuresis. Trials focused solely on daytime wetting and trials of adults with nocturnal enuresis were excluded.

**Data collection and analysis:** 
Two reviewers independently assessed the quality of the eligible trials and extracted data. Differences between reviewers were settled by discussion with a third reviewer.

**Main results:** 
Sixteen trials met the inclusion criteria, involving 1643 children of whom 865 received a simple behavioural intervention. Within each comparison, outcomes were mostly addressed by single trials, precluding meta-analysis. The only exception was bladder training versus enuresis alarm therapy which included two studies and demonstrated that alarm therapy was superior to bladder training.In single small trials, rewards, lifting and waking and bladder training were each associated with significantly fewer wet nights, higher full response rates and lower relapse rates compared to controls. Simple behavioural interventions appeared to be less effective when compared with other known effective interventions (such as enuresis alarm therapy and drug therapies with imipramine and amitriptyline). However, the effect was not sustained at follow-up after completion of treatment for the drug therapies. Based on one small trial, cognitive therapy also appeared to be more effective than rewards. When one simple behavioural therapy was compared with another, there did not appear to be one therapy that was mor ffective than another.

**Authors&#039; conclusions:** 
Simple behavioural methods may be superior to no active treatment but appear to be inferior to enuresis alarm therapy and some drug therapy (such as imipramine and amitriptyline). Simple behavioural therapies could be tried as first line treatment before considering enuresis alarm therapy or drug therapy, which may be more demanding and have adverse effects, although evidence supporting their efficacy is lacking.
AN  - CD003637
AU  - Caldwell,
AU  - P.
AU  - H.
AU  - Nankivell,
AU  - G.
AU  - Sureshkumar,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003637.pub3
KW  - Antidepressive Agents, Tricyclic [therapeutic use]
KW  - Clinical Alarms
KW  - Cognitive Therapy [methods]
KW  - Deamino Arginine Vasopressin [therapeutic use]
KW  - Enuresis [drug therapy] [therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Renal Agents [therapeutic use]
KW  - Reward
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Incont
PY  - 2013
T2  - Cochrane Database of Systematic Reviews
TI  - Simple behavioural interventions for nocturnal enuresis in children
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003637.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003637.pub3/asset/CD003637.pdf?v=1&amp;t=iw7l629q&amp;s=0a0ef0406041c365d8d9edc08748d7871ddc552b
ER  -
TY  - JOUR
AB  - This meta-analysis examined the effects of juvenile delinquency interventions on academic outcomes. 

After retrieving over 250 reports, 15 reports met inclusion criteria and provided 134 effect sizes (92 unadjusted and 42 adjusted) based on 20 separate samples in a variety of settings, including school, community, and juvenile justice settings. Heterogeneity of the samples, generally weak research designs, and the absence of control conditions in many recovered reports was a limitation in the existing research. 

Overall, there were limited positive effects of juvenile delinquency interventions on academic outcomes. The lack of theory-driven or empirically supported academic interventions was notable. Studies with the weakest designs produced the largest effects on academic achievement, and school attendance outcomes were enhanced only for older adolescents. 

The implications of findings for future research and policy are discussed. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Sander, Janay B.: Janay.sander@mail.utexas.edu Sander, Janay B.: Department of Educational Psychology, University of Texas at Austin, 1 University Station mail stop D5800, Austin, TX, US, 78712, Janay.sander@mail.utexas.edu Sander, Janay B.: University of Texas at Austin, Austin, TX, US Patall, Erika A.: University of Texas at Austin, Austin, TX, US Amoscato, Laura A.: University of Texas at Austin, Austin, TX, US Fisher, Alexandra L.: University of Texas at Austin, Austin, TX, US Funk, Catherine: University of Texas at Austin, Austin, TX, US
AN  - 2012-13625-001
AU  - Sander,
AU  - J.
AU  - B.
AU  - Patall,
AU  - E.
AU  - A.
AU  - Amoscato,
AU  - L.
AU  - A.
AU  - Fisher,
AU  - A.
AU  - L.
AU  - Funk,
AU  - C.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2012.04.005
DP  - Ovid Technologies
KW  - juvenile delinquency, intervention, academic outcomes, juvenile justice *Academic Achievement *Juvenile Delinquency *Juvenile Justice *School Based Intervention Educational Psychology [3500] Human
LA  - English
M3  - Meta Analysis
PY  - 2012
SP  - 1695-1708
T2  - Children and Youth Services Review
TI  - A meta-analysis of the effect of juvenile delinquency interventions on academic outcomes
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc9&amp;AN=2012-13625-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2012.04.005&amp;issn=0190-7409&amp;isbn=&amp;volume=34&amp;issue=9&amp;spage=1695&amp;pages=1695-1708&amp;date=2012&amp;title=Children+and+Youth+Services+Review&amp;atitle=A+meta-analysis+of+the+effect+of+juvenile+delinquency+interventions+on+academic+outcomes.&amp;aulast=Sander&amp;pid=%3Cauthor%3ESander%2C+Janay+B%3C%2Fauthor%3E%3CAN%3E2012-13625-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0190740912001636/1-s2.0-S0190740912001636-main.pdf?_tid=15e9d9c8-18cd-11e5-bce8-00000aacb35e&amp;acdnat=1434970662_e49c411143837382f206556bc08c2db5
VL  - 34
ER  -
TY  - JOUR
AB  - This paper provides a comprehensive quantitative review of high quality randomized controlled trials of psychological therapies for anxiety disorders in children and young people. 

Using a systematic search for randomized controlled trials which included a control condition and reported data suitable for meta-analysis, 55 studies were included. 

Eligible studies were rated for methodological quality and outcome data were extracted and analyzed using standard methods. 

Trial quality was variable, many studies were underpowered and adverse effects were rarely assessed; however, quality ratings were higher for more recently published studies. 

Most trials evaluated cognitive behavior therapy or behavior therapy and most recruited both children and adolescents. Psychological therapy for anxiety in children and young people was moderately effective overall, but effect sizes were small to medium when psychological therapy was compared to an active control condition. 

The effect size for non-CBT interventions was not significant. Parental involvement in therapy was not associated with differential effectiveness. 

Treatment targeted at specific anxiety disorders, individual psychotherapy, and psychotherapy with older children and adolescents had effect sizes which were larger than effect sizes for treatments targeting a range of anxiety disorders, group psychotherapy, and psychotherapy with younger children. 

Few studies included an effective follow-up. Future studies should follow CONSORT reporting standards, be adequately powered, and assess follow-up. 

Research trials are unlikely to address all important clinical questions around treatment delivery. 

Thus, careful assessment and formulation will remain an essential part of successful psychological treatment for anxiety in children and young people. 

(C) 2012 Elsevier Ltd. All rights reserved.
AD  - [Reynolds, Shirley; Wilson, Charlotte; Austin, Joanne; Hooper, Lee] Univ E Anglia, Norwich Med Sch, Dept Psychol Sci, Norwich NR4 7QH, Norfolk, England. Reynolds, S (reprint author), Univ E Anglia, Norwich Med Sch, Dept Psychol Sci, Norwich NR4 7QH, Norfolk, England. s.reynolds@uea.ac.uk
AN  - WOS:000303701800004
AU  - Reynolds,
AU  - S.
AU  - Wilson,
AU  - C.
AU  - Austin,
AU  - J.
AU  - Hooper,
AU  - L.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2012.01.005
J2  - Clin. Psychol. Rev.
KW  - Anxiety disorders Children and adolescents Psychotherapy Metaanalysis COGNITIVE-BEHAVIORAL THERAPY RANDOMIZED CONTROLLED-TRIAL OBSESSIVE-COMPULSIVE DISORDER SCHOOL-BASED INTERVENTION AUTISM SPECTRUM DISORDERS CHILDHOOD SOCIAL PHOBIA ONE-SESSION TREATMEN
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 937ZD Times Cited: 38 Cited Reference Count: 99 Reynolds, Shirley Wilson, Charlotte Austin, Joanne Hooper, Lee Hooper, Lee/D-2795-2009 Hooper, Lee/0000-0002-7904-3331 38 PERGAMON-ELSEVIER SCIENCE LTD OXFORD CLIN PSYCHOL REV
PY  - 2012
SP  - 251-262
T2  - Clinical Psychology Review
TI  - Effects of psychotherapy for anxiety in children and adolescents: A meta-analytic review
UR  - &lt;Go to ISI&gt;://WOS:000303701800004http://ac.els-cdn.com/S0272735812000219/1-s2.0-S0272735812000219-main.pdf?_tid=64940508-1972-11e5-b06d-00000aacb362&amp;acdnat=1435041661_90dc0df4ae8270c9df4dd09b7dee3f1d
VL  - 32
ER  -
TY  - JOUR
AB  - Nonsuicidal self-injury (NSSI) is a concern in the adolescent population given its relationship to suicidal behavior, pointing to the serious need for adequate treatments for this high-risk population. 

This review examined empirical studies that evaluated treatments for NSSI among adolescents, and evaluated how the components of each treatment address common underlying and concurrent factors of NSSI. 

Among the available treatments, cognitive-behavioral therapy (CBT) interventions that integrate a problem-solving component and dialectical behavior therapy (DBT) have received the most empirical attention. 

However, studies examining the utility of cognitive-behavioral problem- solving interventions for adolescents, and randomized controlled trials examining the efficacy of DBT are lacking. 

Overall, CBT-based treatments improved underlying or maintaining factors of NSSI, such as depression, hopelessness, and problem-solving skills. DBT was effective for reducing hospitalizations. 

No existing studies evaluated treatment effectiveness for NSSI exclusively, and few studies used a purely adolescent sample. This review highlights the gap in knowledge regarding adolescent NSSI-there is no strong evidence for the efficacy of any specific treatment. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Brausch, Amy M.: amy.brausch@wku.edu Brausch, Amy M.: Western Kentucky University, 1906 College Heights Boulevard, Bowling Green, KY, US, 42101, amy.brausch@wku.edu Brausch, Amy M.: Western Kentucky University, Department of Psychology, Bowling Green, KY, US
AN  - 2012-04814-001
AU  - Brausch,
AU  - A.
AU  - M.
AU  - Girresch,
AU  - S.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1891/0889-8391.26.1.3
DP  - Ovid Technologies
KW  - adolescent non suicidal self injury, cognitive behavioral therapy *Cognitive Behavior Therapy *Self Injurious Behavior Adolescent Psychopathology Behavior Disorders &amp; Antisocial Behavior [3230] Cognitive Therapy [3311] Human
LA  - English
M3  - Literature Review
PY  - 2012
SP  - 3-18
T2  - Journal of Cognitive Psychotherapy
TI  - A review of empirical treatment studies for adolescents non suicidal self-injury
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc9&amp;AN=2012-04814-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1891%2F0889-8391.26.1.3&amp;issn=0889-8391&amp;isbn=&amp;volume=26&amp;issue=1&amp;spage=3&amp;pages=3-18&amp;date=2012&amp;title=Journal+of+Cognitive+Psychotherapy&amp;atitle=A+review+of+empirical+treatment+studies+for+adolescents+non+suicidal+self-injury.&amp;aulast=Brausch&amp;pid=%3Cauthor%3EBrausch%2C+Amy+M%3C%2Fauthor%3E%3CAN%3E2012-04814-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 26
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To examine the informativeness of open-label trials toward predicting results in subsequent randomized, placebo-controlled clinical trials of psychopharmacologic treatments for pediatric bipolar disorder. 

**DATA SOURCES: **
We searched journal articles through PubMed at the National Library of Medicine using bipolar disorder, mania, pharmacotherapy, treatment and clinical trial as keywords. This search was supplemented with scientific presentations at national and international scientific meetings and submitted manuscripts from our group. 

**STUDY SELECTION: **
Selection criteria included (1) enrollment of children diagnosed with DSM-IV bipolar disorder; (2) prospective assessment of at least 3 weeks; (3) monotherapy of a pharmacologic treatment for bipolar disorder; (4) use of a randomized placebo-controlled design or an open-label design for the same therapeutic compound; and (5) repeated use of the Young Mania Rating Scale (YMRS) as an outcome. 

**DATA EXTRACTION: **
The following information and data were extracted from 14 studies: study design, name of medication, class of medication, dose of medication, sample size, age, sex, trial length, and YMRS mean and standard deviation baseline and follow-up scores. 

**RESULTS: **
For both study designs, the pooled effect size was statistically significant (open-label studies, z = 8.88, P &lt; .001; randomized placebo-controlled studies, z = 13.75, P &lt; .001), indicating a reduction in the YMRS from baseline to endpoint in both study designs. In a meta-analysis regression, study design was not a significant predictor of mean change in the YMRS. 

**CONCLUSIONS: **
We found similarities in the treatment effects between open-label and randomized placebo-controlled studies in youth with bipolar disorder indicating that open-label studies are useful predictors of the potential safety and efficacy of a given compound in the treatment of pediatric bipolar disorder.

&copy; Copyright 2012 Physicians Postgraduate Press, Inc.
AD  - Biederman,Joseph. Clinical and Research Program in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, MA 02114, USA. jbiederman@partners.org
AN  - 22154898
AU  - Biederman,
AU  - J.
AU  - Petty,
AU  - C.
AU  - R.
AU  - Woodworth,
AU  - K.
AU  - Y.
AU  - Lomedico,
AU  - A.
AU  - O&#039;
AU  - Connor,
AU  - K.
AU  - B.
AU  - Wozniak,
AU  - J.
AU  - Faraone,
AU  - S.
AU  - V.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.4088/JCP.10m06490
DP  - Ovid Technologies
J2  - J Clin Psychiatry
KW  - *Bipolar Disorder/dt [Drug Therapy] *Child Clinical Trials as Topic/sn [Statistics &amp; Numerical Data] Humans *Psychotropic Drugs/tu [Therapeutic Use] *Randomized Controlled Trials as Topic/sn [Statistics &amp; Numerical Data] Research Design/sn [Statistics &amp;
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Biederman, Joseph Petty, Carter R Woodworth, K Yvonne Lomedico, Alexandra O&#039;Connor, Katherine B Wozniak, Janet Faraone, Stephen V
PY  - 2012
SP  - 358-65
T2  - Journal of Clinical Psychiatry
TI  - How informative are open-label studies for youth with bipolar disorder? A meta-analysis comparing open-label versus randomized, placebo-controlled clinical trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22154898 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22154898&amp;id=doi:10.4088%2FJCP.10m06490&amp;issn=0160-6689&amp;isbn=&amp;volume=73&amp;issue=3&amp;spage=358&amp;pages=358-65&amp;date=2012&amp;title=Journal+of+Clinical+Psychiatry&amp;atitle=How+informative+are+open-label+studies+for+youth+with+bipolar+disorder%3F+A+meta-analysis+comparing+open-label+versus+randomized%2C+placebo-controlled+clinical+trials.&amp;aulast=Biederman&amp;pid=%3Cauthor%3EBiederman+J%3C%2Fauthor%3E%3CAN%3E22154898%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.psychiatrist.com/JCP/article/Pages/2012/v73n03/v73n0312.aspx
UR  - http://www.psychiatrist.com/jcp/article/pages/2012/v73n03/v73n0312.aspx
VL  - 73
ER  -
TY  - JOUR
AB  - **Background:** 
In 1998 secretin, a gastrointestinal hormone, was suggested as an effective treatment for autism spectrum disorders (ASD) based on anecdotal evidence.

**Objectives:** 
To assess whether intravenous secretin improves the core features of ASD, other aspects of behaviour or function such as self-injurious behaviour, and the quality of life of affected individuals and their carers. We also assessed whether secretin causes harm. This is an updated version of our review of this topic originally published in 2005.

**Search methods:** 
We searched CENTRAL (2010 Issue 1), MEDLINE (1950 to January 2010) , EMBASE (1980 to 2010 Week 2), PsycINFO (1806 to 2010 Week 2), CINAHL (1938 to January 2010), ERIC (1966 to January 2010), Sociological Abstracts (1952 to January 2010). Sociofile and HealthStar were searched in March 2005 when this review was first published, but were not available for this update. Records were limited to studies published since 1998 as this is when secretin was first proposed as a possible treatment for ASD. We searched reference lists of trials and reviews; we also contacted experts and trialists to find unpublished studies.

**Selection criteria:** 
Randomised controlled trials of intravenous secretin compared to a placebo treatment in children or adults diagnosed with ASD, where at least one standardised outcome measure was reported.

**Data collection and analysis**: 
Sixteen studies met the inclusion criteria but for two of these, conducted by Repligen, the only available multisite data were reported in press releases. All outcome data from the other 14 trials were continuous. Where trials used cross-over designs, we conducted analysis on results from the first treatment phase. Where mean change from baseline was reported, we used this in preference to post-treatment scores for meta-analyses or forest plots. Meta-analysis was able to be attempted for only one outcome (Childhood Autism Rating Scale). Insufficient data were available to conduct sensitivity or subgroup analyses to assess the impact of study quality, clinical differences in the intervention or clinically relevant differences between groups, such as age or presence of gastrointestinal symptoms.

**Main results:** 
Over 900 children were recruited for the secretin trials. Twenty-five established standardised outcome measures were reported to assess core features of ASD, communication, behaviour, visuospatial skills, affect and adverse events. One standardised measure of global impression was also used. No more than four studies used any one outcome measure similarly. When duration from the start of the intervention to outcome assessment was known, outcomes were reported at between three and six weeks. Meta-analysis of data was not possible but there is now consistency of findings, with RCTs of the efficacy of secretin in autism not showing improvements for core features of ASD.

**Authors&#039; conclusions:** 
There is no evidence that single or multiple dose intravenous secretin is effective and as such currently it should not be recommended or administered as a treatment for ASD. Further experimental assessment of secretin&#039;s effectiveness for ASD can only be justified if there is new high-quality and replicated scientific evidence that either finds that secretin has a role in neurotransmission in a way that could benefit all children with ASD or identifies important subgroups of children with ASD who could benefit from secretin because of a proven link between the action of secretin and the known cause of their ASD, or the type of problems they are experiencing.
AN  - CD003495
AU  - Williams,
AU  - K.
AU  - Wray,
AU  - J.
AU  - A.
AU  - Wheeler,
AU  - D.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003495.pub3
KW  - Autistic Disorder [drug therapy] [psychology]
KW  - Behavior [drug effects]
KW  - Communication
KW  - Gastrointestinal Agents [administration &amp; dosage]
KW  - Hormones [administration &amp; dosage]
KW  - Injections, Intravenous
KW  - Randomized Controlled Trials as Topic
KW  - Secretin [administration &amp; dosage]
KW  - Treatment Outcome
KW  - Humans[checkword]
KW  - Behav
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Intravenous secretin for autism spectrum disorders (ASD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003495.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003495.pub3/asset/CD003495.pdf?v=1&amp;t=iw7jwmqj&amp;s=b95537f4b8d40527f01aa83aeeb239a1848589b6
ER  -
TY  - JOUR
AB  - **Purpose:** 
The objective of this research was to systematically review quasi-experimental and experimental evaluations of the effectiveness of drug courts in reducing offending. 

**Methods: **
Our search identified 154 independent evaluations: 92 evaluations of adult drug courts, 34 of juvenile drug courts, and 28 of DWI drug courts. The findings of these studies were synthesized using meta-analysis. 

**Results: **
The vast majority of adult drug court evaluations, even the most rigorous evaluations, find that participants have lower recidivism than non-participants. The average effect of participation is analogous to a drop in recidivism from 50% to 38%; and, these effects last up to three years. Evaluations of DWI drug courts find effects similar in magnitude to those of adult drug courts, but the most rigorous evaluations do not uniformly find reductions in recidivism. Juvenile drug courts have substantially smaller effects on recidivism. Larger reductions in recidivism were found in adult drug courts that had high graduation rates, and those that accepted only non-violent offenders. 

**Conclusions: **
These findings support the effectiveness of adult drug courts in reducing recidivism. The evidence assessing DWI courts&#039; effectiveness is very promising but more experimental evaluations are needed. Juvenile drug courts typically produce small reductions in recidivism. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Mitchell, Ojmarrh: omitchell@usf.edu; Wilson, David B.: dwilsonb@gmu.edu; Eggers, Amy: aeggers@mail.usf.edu; MacKenzie, Doris L.: dlm69@psu.edu Mitchell, Ojmarrh: Department of Criminology, University of South Florida, 4202 E. Fowler Ave. SOC107, Tampa, FL, US, 33620, omitchell@usf.edu Mitchell, Ojmarrh: Department of Criminology, University of South Florida, Tampa, FL, US Wilson, David B.: George Mason University, Fairfax, VA, US Eggers, Amy: Department of Criminology, University of South Florida, Tampa, FL, US MacKenzie, Doris L.: Pennsylvania State University, University Park, PA, US
AN  - 2012-03965-009
AU  - Mitchell,
AU  - O.
AU  - Wilson,
AU  - D.
AU  - B.
AU  - Eggers,
AU  - A.
AU  - MacKenzie,
AU  - D.
AU  - L.
DA  - Jan-Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jcrimjus.2011.11.009
DP  - Ovid Technologies
KW  - drug courts, recidivism, traditional, non-traditional *Adjudication *Court Referrals *Drug Abuse *Drug Addiction *Recidivism Criminal Rehabilitation &amp; Penology [3386] Human
LA  - English
M3  - Meta Analysis
PY  - 2012
SP  - 60-71
T2  - Journal of Criminal Justice
TI  - Assessing the effectiveness of drug courts on recidivism: A meta-analytic review of traditional and non-traditional drug courts
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc9&amp;AN=2012-03965-009 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jcrimjus.2011.11.009&amp;issn=0047-2352&amp;isbn=&amp;volume=40&amp;issue=1&amp;spage=60&amp;pages=60-71&amp;date=2012&amp;title=Journal+of+Criminal+Justice&amp;atitle=Assessing+the+effectiveness+of+drug+courts+on+recidivism%3A+A+meta-analytic+review+of+traditional+and+non-traditional+drug+courts.&amp;aulast=Mitchell&amp;pid=%3Cauthor%3EMitchell%2C+Ojmarrh%3C%2Fauthor%3E%3CAN%3E2012-03965-009%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0047235211001255/1-s2.0-S0047235211001255-main.pdf?_tid=7a281d9a-1671-11e5-a5e4-00000aab0f26&amp;acdnat=1434711414_95c4b11bda636c5c16187df90072a18b
VL  - 40
ER  -
TY  - JOUR
AB  - Outreach workers meet with street-involved youth in their environment, and attempt to engage them in services vital to their well-being. 

The goal of this study is to conduct a systematic review of both the quantitative and qualitative research that explores outreach with street-involved youth. Using 16 outreach programs with quantitative information, our meta-analysis found that 63% of youth who are contacted through outreach later participate in the offered service. 

Our meta-synthesis of 31 qualitative articles on outreach uncovered 13 themes across 4 conceptual domains of interest. Themes pertaining to the therapeutic relationship, flexibility, and youth-centric programming had a large presence among the majority of the articles. 

Outreach with street-involved youth, when characterized through a strong bond between worker and youth, is an effective strategy for involving youth in agency services. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - A E Connolly, J. A.: Connolly@yorku.ca; Joly, L. E.: ljoly@yorku.ca Joly, L. E.: York University, 5022 TEL, 4700 Keele St., Toronto, ON, Canada, M3J 1P3, ljoly@yorku.ca Connolly, J. A.: York University, Toronto, ON, Canada Joly, L. E.: York University, Toronto, ON, Canada
AN  - 2012-22130-008
AU  - Connolly,
AU  - J.
AU  - Joly,
AU  - L.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2012.05.006
DP  - Ovid Technologies
KW  - outreach programs, street involvement, well being, homeless, youth *Homeless *Outreach Programs Community &amp; Social Services [3373] Human Childhood (birth-12 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs) Adulthood (18 yrs &amp; older) Young Adulthood (1
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2012
SP  - 524-534
T2  - Clinical Psychology Review
TI  - Outreach with street-involved youth: A quantitative and qualitative review of the literature
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc9&amp;AN=2012-22130-008 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.cpr.2012.05.006&amp;issn=0272-7358&amp;isbn=&amp;volume=32&amp;issue=6&amp;spage=524&amp;pages=524-534&amp;date=2012&amp;title=Clinical+Psychology+Review&amp;atitle=Outreach+with+street-involved+youth%3A+A+quantitative+and+qualitative+review+of+the+literature.&amp;aulast=Connolly&amp;pid=%3Cauthor%3EConnolly%2C+J.+A%3C%2Fauthor%3E%3CAN%3E2012-22130-008%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735812000700/1-s2.0-S0272735812000700-main.pdf?_tid=25f6ece8-1972-11e5-887b-00000aab0f26&amp;acdnat=1435041555_5f6546ad197f1871efe324ce2d2a0c39
VL  - 32
ER  -
TY  - JOUR
AB  - A meta-analysis of 27 controlled studies, including 17,038 youth, was conducted to examine the effectiveness of institutional youth care over the past three decades. 

We compared institutional evidence-based treatment (EBT) with non-institutional EBT, institutional care as usual (CAU) with non-institutional CAU, institutional CAU with non-institutional EBT, and institutional EBT with institutional CAU. Only the last comparison yielded a significant and small-to-medium effect (d = .36), which not only shows that institutional youth care can be equally effective as non-institutional youth care, but also demonstrates that it seems more effective to provide youth with EBT during their stay in the institution. 

Furthermore, moderator analyses indicated that only cognitive behavior therapy showed a significant and medium effect (d = .50), whereas (social) skills training and care as usual showed no effect. 

Age, gender, type of outcome measure (delinquency, skills, problem behavior, and overall problems) and study design characteristics (randomized, matched or non-matched controls) did not influence the results. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - J. w J. j. m J H A H. p De Swart, J. J. W.: jdeswart@home.nl De Swart, J. J. W., jdeswart@home.nl De Swart, J. J. W.: Saxion University of Applied Science, Netherlands Van den Broek, H.: University of Amsterdam, Amsterdam, Netherlands Stams, G. J. J. M.: University of Amsterdam, Amsterdam, Netherlands Asscher, J. J.: University of Amsterdam, Amsterdam, Netherlands Van der Laan, P. H.: Vrije Universiteit, Netherlands Holsbrink-Engels, G. A.: Saxion University of Applied Science, Netherlands Van der Helm, G. H. P.: University of Applied Sciences, Leiden, Netherlands
AN  - 2012-15604-001
AU  - De
AU  - Swart,
AU  - J.
AU  - Van
AU  - den
AU  - Broek,
AU  - H.
AU  - Stams,
AU  - G.
AU  - Asscher,
AU  - J.
AU  - Van
AU  - der
AU  - Laan,
AU  - P.
AU  - Holsbrink-Engels,
AU  - G.
AU  - Van
AU  - der
AU  - Helm,
AU  - G.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2012.05.015
DP  - Ovid Technologies
KW  - institutional youth care, group homes, incarceration, treatment *Residential Care Institutions *Treatment Group Homes Incarceration Juvenile Delinquency Health &amp; Mental Health Treatment &amp; Prevention [3300] Human Childhood (birth-12 yrs) Adolescence (13-
LA  - English
M3  - Meta Analysis
PY  - 2012
SP  - 1818-1824
T2  - Children and Youth Services Review
TI  - The effectiveness of institutional youth care over the past three decades: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc9&amp;AN=2012-15604-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2012.05.015&amp;issn=0190-7409&amp;isbn=&amp;volume=34&amp;issue=9&amp;spage=1818&amp;pages=1818-1824&amp;date=2012&amp;title=Children+and+Youth+Services+Review&amp;atitle=The+effectiveness+of+institutional+youth+care+over+the+past+three+decades%3A+A+meta-analysis.&amp;aulast=De+Swart&amp;pid=%3Cauthor%3EDe+Swart%2C+J.+J.+W%3C%2Fauthor%3E%3CAN%3E2012-15604-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0190740912002204/1-s2.0-S0190740912002204-main.pdf?_tid=32f1f906-18cd-11e5-b329-00000aab0f01&amp;acdnat=1434970710_b5ecd716ac0711df7d5d61da63fdab3a
VL  - 34
ER  -
TY  - JOUR
AB  - **Background:** 
Common mental health problems, such as depression and anxiety, are estimated to affect up to 15% of the UK population at any one time, and health care systems worldwide need to implement interventions to reduce the impact and burden of these conditions. Collaborative care is a complex intervention based on chronic disease management models that may be effective in the management of these common mental health problems.

**Objectives:** 
To assess the effectiveness of collaborative care for patients with depression or anxiety.

**Search methods:** 
We searched the following databases to February 2012: The Cochrane Collaboration Depression, Anxiety and Neurosis Group (CCDAN) trials registers (CCDANCTR-References and CCDANCTR-Studies) which include relevant randomised controlled trials (RCTs) from MEDLINE (1950 to present), EMBASE (1974 to present), PsycINFO (1967 to present) and the Cochrane Central Register of Controlled Trials (CENTRAL, all years); the World Health Organization (WHO) trials portal (ICTRP); ClinicalTrials.gov; and CINAHL (to November 2010 only). We screened the reference lists of reports of all included studies and published systematic reviews for reports of additional studies.

**Selection criteria:** 
Randomised controlled trials (RCTs) of collaborative care for participants of all ages with depression or anxiety.

**Data collection and analysis:** 
Two independent researchers extracted data using a standardised data extraction sheet. Two independent researchers made &#039;Risk of bias&#039; assessments using criteria from The Cochrane Collaboration. We combined continuous measures of outcome using standardised mean differences (SMDs) with 95% confidence intervals (CIs). We combined dichotomous measures using risk ratios (RRs) with 95% CIs. Sensitivity analyses tested the robustness of the results.

**Main results:** 
We included seventy-nine RCTs (including 90 relevant comparisons) involving 24,308 participants in the review. Studies varied in terms of risk of bias.The results of primary analyses demonstrated significantly greater improvement in depression outcomes for adults with depression treated with the collaborative care model in the short-term (SMD -0.34, 95% CI -0.41 to -0.27; RR 1.32, 95% CI 1.22 to 1.43), medium-term (SMD -0.28, 95% CI -0.41 to -0.15; RR 1.31, 95% CI 1.17 to 1.48), and long-term (SMD -0.35, 95% CI -0.46 to -0.24; RR 1.29, 95% CI 1.18 to 1.41). However, these significant benefits were not demonstrated into the very long-term (RR 1.12, 95% CI 0.98 to 1.27).The results also demonstrated significantly greater improvement in anxiety outcomes for adults with anxiety treated with the collaborative care model in the short-term (SMD -0.30, 95% CI -0.44 to -0.17; RR 1.50, 95% CI 1.21 to 1.87), medium-term (SMD -0.33, 95% CI -0.47 to -0.19; RR 1.41, 95% CI 1.18 to 1.69), and long-term (SMD -0.20, 95% CI -0.34 to -0.06; RR 1.26, 95% CI 1.11 to 1.42). No comparisons examined the effects of the intervention on anxiety outcomes in the very long-term.There was evidence of benefit in secondary outcomes including medication use, mental health quality of life, and patient satisfaction, although there was less evidence of benefit in physical quality of life.

**Authors&#039; conclusions:** 
Collaborative care is associated with significant improvement in depression and anxiety outcomes compared with usual care, and represents a useful addition to clinical pathways for adult patients with depression and anxiety.
AN  - CD006525
AU  - Archer,
AU  - J.
AU  - Bower,
AU  - P.
AU  - Gilbody,
AU  - S.
AU  - Lovell,
AU  - K.
AU  - Richards,
AU  - D.
AU  - Gask,
AU  - L.
AU  - Dickens,
AU  - C.
AU  - Coventry,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd006525
KW  - Interprofessional Relations
KW  - Anxiety [therapy]
KW  - Case Management [organization &amp; administration]
KW  - Depression [therapy]
KW  - Patient Care Team [organization &amp; administration]
KW  - Primary Health Care [organization &amp; administration]
KW  - Psychiatric Nursing
KW  - Psychiatry
KW  - Psychology
KW  - Randomized Controlled Trials as Topic
KW  - Standard of Care
KW  - Adult[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Depressn
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Collaborative care for depression and anxiety problems
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006525.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006525.pub2/asset/CD006525.pdf?v=1&amp;t=iw7j58c4&amp;s=af7274d164181456909f2afd45ca8ee6b2269b33
ER  -
TY  - JOUR
AB  - **Background:** 
The morbidity caused by postnatal depression is enormous. Several psychological or psychosocial interventions have appeared to be effective for treating the disorder although they have not shown a clear benefit in preventing the development of PND. As yet however, the effectiveness of hypnosis has not been evaluated in relation to this.

**Objectives:** 
To assess the effect of hypnosis for preventing postnatal depression compared with usual antenatal, intranatal, or postnatal care.

**Search methods:** 
We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (30 September 2011).

**Selection criteria:** 
Randomised controlled trials comparing hypnosis with usual antenatal, intranatal, or postnatal care, where the primary or secondary objective is to assess whether there is a reduced risk of developing postnatal depression.

**Data collection and analysis:** 
Two review authors independently assessed trials for inclusion and assessed the one included study for risk of bias. The included study did not contribute any data for analysis.

**Main results:** 
There was one included study (involving 63 women). However, as it did not include the outcomes of interest, no data were available for analysis for this review.

**Authors&#039; conclusions:**
There was no evidence available from randomised controlled trials to assess the effectiveness of hypnosis during pregnancy, childbirth, and the postnatal period for preventing postnatal depression. Evidence from randomised controlled trials is needed to evaluate the use and effects of hypnosis during the perinatal period to prevent postnatal depression. Two trials are currently underway which may provide further information in the future.
AN  - CD009062
AU  - Sado,
AU  - M.
AU  - Ota,
AU  - E.
AU  - Stickley,
AU  - A.
AU  - Mori,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009062
KW  - Hypnosis
KW  - Delivery, Obstetric [psychology]
KW  - Depression, Postpartum [prevention &amp; control]
KW  - Randomized Controlled Trials as Topic
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Pregnancy[checkword]
KW  - Preg
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Hypnosis during pregnancy, childbirth, and the postnatal period for preventing postnatal depression
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009062.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009062.pub2/asset/CD009062.pdf?v=1&amp;t=iw7jos6y&amp;s=2bf504987479b3c3940695511a551a18af2db6b0
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The demand for clinically efficacious, safe, patient acceptable, and cost-effective forms of treatment for mental illness is growing. Several studies have demonstrated benefit from yoga in specific psychiatric symptoms and a general sense of well-being. 

**OBJECTIVE: **
To systematically examine the evidence for efficacy of yoga in the treatment of selected major psychiatric disorders. 

**METHODS: **
Electronic searches of The Cochrane Central Register of Controlled Trials and the standard bibliographic databases, MEDLINE, EMBASE, and PsycINFO, were performed through April 2011 and an updated in June 2011 using the keywords yoga AND psychiatry OR depression OR anxiety OR schizophrenia OR cognition OR memory OR attention AND randomized controlled trial (RCT). Studies with yoga as the independent variable and one of the above mentioned terms as the dependent variable were included and exclusion criteria were applied. 

**RESULTS: **
The search yielded a total of 124 trials, of which 16 met rigorous criteria for the final review. Grade B evidence supporting a potential acute benefit for yoga exists in depression (four RCTs), as an adjunct to pharmacotherapy in schizophrenia (three RCTs), in children with ADHD (two RCTs), and Grade C evidence in sleep complaints (three RCTs). RCTs in cognitive disorders and eating disorders yielded conflicting results. No studies looked at primary prevention, relapse prevention, or comparative effectiveness versus pharmacotherapy. 

**CONCLUSION: **
There is emerging evidence from randomized trials to support popular beliefs about yoga for depression, sleep disorders, and as an augmentation therapy. Limitations of literature include inability to do double-blind studies, multiplicity of comparisons within small studies, and lack of replication. Biomarker and neuroimaging studies, those comparing yoga with standard pharmaco- and psychotherapies, and studies of long-term efficacy are needed to fully translate the promise of yoga for enhancing mental health.
AD  - Balasubramaniam,Meera. Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine Durham, NC, USA.
AN  - 23355825
AU  - Balasubramaniam,
AU  - M.
AU  - Telles,
AU  - S.
AU  - Doraiswamy,
AU  - P.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
J2  - Front Psychiatr
L1  - internal-pdf://0057392344/Balasubramaniam-2012-Yoga on our minds_ a syst.pdf
LA  - English
N1  - Balasubramaniam, Meera Telles, Shirley Doraiswamy, P Murali
PY  - 2012
SP  - 117
T2  - Frontiers in psychiatry Frontiers Research Foundation
TI  - Yoga on our minds: a systematic review of yoga for neuropsychiatric disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=23355825 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23355825&amp;id=doi:10.3389%2Ffpsyt.2012.00117&amp;issn=1664-0640&amp;isbn=&amp;volume=3&amp;issue=&amp;spage=117&amp;pages=117&amp;date=2012&amp;title=Frontiers+in+psychiatry+Frontiers+Research+Foundation&amp;atitle=Yoga+on+our+minds%3A+a+systematic+review+of+yoga+for+neuropsychiatric+disorders.&amp;aulast=Balasubramaniam&amp;pid=%3Cauthor%3EBalasubramaniam+M%3C%2Fauthor%3E%3CAN%3E23355825%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555015/pdf/fpsyt-03-00117.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555015/pdf/fpsyt-03-00117.pdf
VL  - 3
ER  -
TY  - JOUR
AB  - **Background: **
Integrated treatment programs (those that include on-site pregnancy-, parenting-, or child-related services with addiction services) were developed to break the intergenerational cycle of addiction, potential child maltreatment, and poor outcomes for children. 

**Objectives: **
To examine the impact and effects of integrated programs for women with substance abuse issues and their children, we performed a systematic review of studies published from 1990 to 2011. 

**Methods: **
Literature search strategies included online bibliographic database searches, checking printed sources, and requests to researchers. Studies were included if all participants were mothers with substance abuse problems at baseline; the treatment program included at least 1 specific substance use treatment and at least 1 parenting or child treatment service; the study design was randomized, quasi-experimental, or cohort; and there were quantitative data on child outcomes. We summarized data on child development, growth, and emotional and behavioral outcomes. 

**Results: **
Thirteen studies (2 randomized trials, 3 quasi-experimental studies, 8 cohort studies; N = 775 children) were included in the review. Most studies using pre-post design indicated improvements in child development (with small to large effects, ds = 0.007-1.132) and emotional and behavioral functioning (with most available effect sizes being large, ds = 0.652-1.132). Comparison group studies revealed higher scores for infants of women in integrated programs than those not in treatment, with regard to development and most growth parameters (length, weight, and head circumference; with all available effect sizes being large, ds = 1.16-2.48). In studies comparing integrated to non-integrated programs, most improvements in emotional and behavioral functioning favored integrated programs and, where available, most effect sizes indicated that this advantage was small (ds = 0.22-0.45). 

**Conclusions:** 
Available evidence supports integrated programs, as findings suggest that they are associated with improvements in child development, growth, and emotional and behavioral functioning. More research is required comparing integrated to non-integrated programs. This review highlights the need for improved methodology, study quality, and reporting to improve our understanding of how best to meet the needs of children of women with substance abuse issues. 

(C) 2012 Elsevier Ltd. All rights reserved.
AD  - [Niccols, Alison; Smith, Ainsley] McMaster Univ, McMaster Childrens Hosp, Hamilton, ON L8N 3Z5, Canada. [Milligan, Karen] Integra, Toronto, ON M5P 1B9, Canada. [Sword, Wendy] McMaster Univ, Sch Nursing HSC 3H48B, Hamilton, ON L8N 3Z5, Canada. [Thabane, Lehana] McMaster Univ, Ctr Evaluat Med, Hamilton, ON L8N 1G6, Canada. [Henderson, Joanna] Ctr Addict &amp; Mental Hlth, Child Youth &amp; Family Program, Toronto, ON M5T 1R8, Canada. Niccols, A (reprint author), McMaster Univ, McMaster Childrens Hosp, 280 Holbrook Bldg,Chedoke Site,Box 2000, Hamilton, ON L8N 3Z5, Canada.
AN  - WOS:000304841200005
AU  - Niccols,
AU  - A.
AU  - Milligan,
AU  - K.
AU  - Smith,
AU  - A.
AU  - Sword,
AU  - W.
AU  - Thabane,
AU  - L.
AU  - Henderson,
AU  - J.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.chiabu.2011.10.007
J2  - Child Abuse Negl.
KW  - Children Mothers Substance abuse Integrated programs RELATIONAL PSYCHOTHERAPY MOTHERS EARLY INTERVENTION WOMEN ALCOHOL RISK METAANALYSIS DISORDERS ADDICTION SERVICES IMPACT Family Studies Psychology, Social Social Work
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 953BF Times Cited: 6 Cited Reference Count: 44 Niccols, Alison Milligan, Karen Smith, Ainsley Sword, Wendy Thabane, Lehana Henderson, Joanna 6 PERGAMON-ELSEVIER SCIENCE LTD OXFORD CHILD ABUSE NEGLECT
PY  - 2012
SP  - 308-322
T2  - Child Abuse &amp; Neglect
TI  - Integrated programs for mothers with substance abuse issues and their children: A systematic review of studies reporting on child outcomes
UR  - &lt;Go to ISI&gt;://WOS:000304841200005http://ac.els-cdn.com/S0145213412000270/1-s2.0-S0145213412000270-main.pdf?_tid=cc5ff32c-18b9-11e5-b3cb-00000aab0f01&amp;acdnat=1434962378_b9f3dfa02986d21ec4dcaffc4f7e289b
VL  - 36
ER  -
TY  - JOUR
AB  - Quetiapine has been proposed for depression in bipolar patients but a quantitative analysis is lacking. 

In the present paper, we review and meta-analyze available data about the short-term and long-term efficacy and tolerability of quetiapine for the depressive phase of bipolar disorder or bipolar depression. 

A literature research was carried out using three electronic databases. Studies providing measures of efficacy and tolerability of quetiapine, either as monotherapy or as augmentation, for bipolar depression were considered. Seven short-term studies and four maintenance studies were included. 

Short-term studies suggested that patients treated with quetiapine monotherapy were significantly more likely than patients treated with placebo and further active comparators to achieve higher response and remission rates as well as more clinical improvements at the endpoint. Such benefits were significant from the first weeks of treatment onward. 

Maintenance studies suggested that the combination of quetiapine and mood stabilizers was significantly better than placebo plus mood stabilizers for the prevention of both depressive and manic relapses. Quetiapine was generally well tolerated. 

Furthermore, several clinical variables moderated outcomes under investigation. In conclusion, quetiapine could have some advantages over traditional treatments for the treatment of bipolar depression. 

&copy; 2012 Wolters Kluwer Health Lippincott Williams &amp; Wilkins.
AD  - (Chiesa, Chierzi, De Ronchi, Serretti) Institute of Psychiatry, University of Bologna, Viale Carlo Pepoli 5, Bologna 40123, Italy A. Serretti, Institute of Psychiatry, University of Bologna, Viale Carlo Pepoli 5, Bologna 40123, Italy. E-mail: alessandro.serretti@unibo.it
AN  - 51727898
AU  - Chiesa,
AU  - A.
AU  - Chierzi,
AU  - F.
AU  - De-Ronch,
AU  - D.
AU  - Serretti,
AU  - A.
DA  - March
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/YIC.0b013e32834e4c56
DP  - Ovid Technologies
KW  - Bipolar depression
KW  - Maintenance
KW  - Quetiapine
KW  - Remission
KW  - Response
KW  - Seroquel
KW  - acid reflux/si [Side Effect]
KW  - adolescent disease/dt [Drug Therapy]
KW  - anxiety
KW  - bipolar depression/dt [Drug Therapy]
KW  - bipolar disorder/dt [Drug Therapy]
KW  - bipolar I disorder/dt [Drug Therapy]
KW  - bipolar mania/dt [Drug Therapy]
KW  - Clinical Global Impression scale
KW  - constipation/si [Side Effect]
KW  - disease severity
KW  - dizziness/si [Side Effect]
KW  - drug dose comparison
KW  - drug dose titration
KW  - drug efficacy
KW  - drug formulation
KW  - drug metabolism
KW  - drug safety
KW  - drug tolerability
KW  - dyspnea/si [Side Effect]
KW  - extrapyramidal symptom/si [Side Effect]
KW  - gastric reflux/si [Side Effect]
KW  - Hamilton scale
KW  - headache/si [Side Effect]
KW  - human
KW  - mania/dt [Drug Therapy]
KW  - meta analysis
KW  - monotherapy
KW  - Montgomery Asberg Depression Rating Scale
KW  - muscle twitch
KW  - myalgia/si [Side Effect]
KW  - nausea/si [Side Effect]
KW  - nightmare/si [Side Effect]
KW  - outcome assessment
KW  - priority journal
KW  - quality of life
KW  - Quality of Life and Enjoyment and Satisfaction Questionnaire
KW  - questionnaire
KW  - randomized controlled trial (topic)
KW  - review
KW  - side effect/si [Side Effect]
KW  - somnolence/si [Side Effect]
KW  - systematic review
KW  - treatment outcome
KW  - treatment response
KW  - weight gain
KW  - xerostomia/si [Side Effect]
KW  - Young Mania Rating Scale
KW  - aripiprazole/ct [Clinical Trial]
KW  - aripiprazole/cm [Drug Comparison]
KW  - aripiprazole/dt [Drug Therapy]
KW  - carbamazepine/dt [Drug Therapy]
KW  - chlorpromazine/dt [Drug Therapy]
KW  - haloperidol/dt [Drug Therapy]
KW  - imipramine/dt [Drug Therapy]
KW  - lamotrigine/ct [Clinical Trial]
KW  - lamotrigine/cb [Drug Combination]
KW  - lamotrigine/dt [Drug Therapy]
KW  - lithium/ct [Clinical Trial]
KW  - lithium/cb [Drug Combination]
KW  - lithium/cm [Drug Comparison]
KW  - lithium/dt [Drug Therapy]
KW  - mood stabilizer/cb [Drug Combination]
KW  - mood stabilizer/dt [Drug Therapy]
KW  - olanzapine/dt [Drug Therapy]
KW  - paroxetine/ct [Clinical Trial]
KW  - paroxetine/cm [Drug Comparison]
KW  - paroxetine/dt [Drug Therapy]
KW  - placebo
KW  - quetiapine/ae [Adverse Drug Reaction]
KW  - quetiapine/ct [Clinical Trial]
KW  - quetiapine/cb [Drug Combination]
KW  - quetiapine/cm [Drug Comparison]
KW  - quetiapine/do [Drug Dose]
KW  - quetiapine/dt [Drug Therapy]
KW  - quetiapine/pd [Pharmacology]
KW  - risperidone/ct [Clinical Trial]
KW  - risperidone/cm [Drug Comparison]
KW  - risperidone/dt [Drug Therapy]
KW  - topiramate/dt [Drug Therapy]
KW  - valproate semisodium/ct [Clinical Trial]
KW  - valproate semisodium/cb [Drug Combination]
KW  - valproate semisodium/dt [Drug Therapy]
KW  - valproic acid/dt [Drug Therapy]
KW  - bipolar disorder
KW  - data base
KW  - patient
KW  - prevention
KW  - quantitative analysis
KW  - relapse
KW  - mood stabilizer
L1  - internal-pdf://2284039618/Chiesa-2012-Quetiapine for bipolar depression_.pdf
LA  - English
M3  - Review
PY  - 2012
SP  - 76-90
T2  - International Clinical Psychopharmacology
TI  - Quetiapine for bipolar depression: A systematic review and meta-analysis
UR  - http://journals.lww.com/intclinpsychopharm/pages/default.aspxhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed18b&amp;AN=51727898http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1097%2FYIC.0b013e32834e4c56&amp;issn=0268-1315&amp;isbn=&amp;volume=27&amp;issue=2&amp;spage=76&amp;pages=76-90&amp;date=2012&amp;title=International+Clinical+Psychopharmacology&amp;atitle=Quetiapine+for+bipolar+depression%3A+A+systematic+review+and+meta-analysis&amp;aulast=Chiesa&amp;pid=%3Cauthor%3EChiesa+A.%3C%2Fauthor%3E%3CAN%3E51727898%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3E
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCDCCBEDAC00/fs046/ovft/live/gv023/00004850/00004850-201203000-00002.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
The role of diet and of food colors in attention-deficit/hyperactivity disorder (ADHD) or its symptoms warrants updated quantitative meta-analysis, in light of recent divergent policy in Europe and the United States. 

**METHOD: **
Studies were identified through a literature search using the PubMed, Cochrane Library, and PsycNET databases through February 2011. Twenty-four publications met inclusion criteria for synthetic food colors; 10 additional studies informed analysis of dietary restriction. A random-effects meta-analytic model generated summary effect sizes. 

**RESULTS: **
Restriction diets reduced ADHD symptoms at an effect of g = 0.29 (95% CI, 0.07-0.53). For food colors, parent reports yielded an effect size of g = 0.18 (95% CI, 0.08-0.24; p = .0007), which decreased to 0.12 (95% CI, 0.01-0.23; p &lt; .05) after adjustment for possible publication bias. The effect was reliable in studies restricted to food color additives (g = 0.21, 95% CI = 0.06-0.36) but did not survive correction for possible publication bias and was not reliable in studies confined to Food and Drug Administration-approved food colors. Teacher/observer reports yielded a nonsignificant effect of 0.07 (95% CI = -0.03 to 0.18; p = .14). However, high-quality studies confined to color additives yielded a reliable effect (g = 0.22, 95% CI = 0.10-0.41, p = .030) that survived correction. In psychometric tests of attention, the summary effect size was 0.27 (95% CI = 0.07-0.47; p = .007) and survived correction. An estimated 8% of children with ADHD may have symptoms related to synthetic food colors. 

**CONCLUSIONS: **
A restriction diet benefits some children with ADHD. Effects of food colors were notable were but susceptible to publication bias or were derived from small, nongeneralizable samples. Renewed investigation of diet and ADHD is warranted.Copyright &copy; 2012 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
AD  - Nigg,Joel T. Oregon Health and Science University, Portland, OR, USA. niggj@ohsu.edu
AN  - 22176942
AU  - Nigg,
AU  - J.
AU  - T.
AU  - Lewis,
AU  - K.
AU  - Edinger,
AU  - T.
AU  - Falk,
AU  - M.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jaac.2011.10.015
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
KW  - *Attention/ph [Physiology] *Attention Deficit Disorder with Hyperactivity/ci [Chemically Induced] *Attention Deficit Disorder with Hyperactivity/dh [Diet Therapy] *Food Coloring Agents/ae [Adverse Effects] Humans Neuropsychological Tests United States 0
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Nigg, Joel T Lewis, Kara Edinger, Tracy Falk, Michael
PY  - 2012
SP  - 86-97.e8
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Meta-analysis of attention-deficit/hyperactivity disorder or attention-deficit/hyperactivity disorder symptoms, restriction diet, and synthetic food color additives
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22176942
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22176942&amp;id=doi:10.1016%2Fj.jaac.2011.10.015&amp;issn=0890-8567&amp;isbn=&amp;volume=51&amp;issue=1&amp;spage=86&amp;pages=86-97.e8&amp;date=2012&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Meta-analysis+of+attention-deficit%2Fhyperactivity+disorder+or+attention-deficit%2Fhyperactivity+disorder+symptoms%2C+restriction+diet%2C+and+synthetic+food+color+additives.&amp;aulast=Nigg&amp;pid=%3Cauthor%3ENigg+JT%3C%2Fauthor%3E%3CAN%3E22176942%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0890856711009531/1-s2.0-S0890856711009531-main.pdf?_tid=127854c8-1674-11e5-bc35-00000aab0f6c&amp;acdnat=1434712528_a8dbb6c8b0cdfc88174c7970d6e02164
VL  - 51
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To develop guidelines for management and treatment of maladaptive aggression in youth in the areas of psychosocial interventions, medication treatments, and side-effect management. 

**METHODS:** 
Evidence was assembled and evaluated in a multistep process, including systematic reviews of published literature; an expert survey of recommended practices; a consensus conference of researchers, policymakers, clinicians, and family advocates; and review by the steering committee of successive drafts of the recommendations. The Center for Education and Research on Mental Health Therapeutics Treatment of Maladaptive Aggression in Youth guidelines reflect a synthesis of the available evidence, based on this multistep process. 

**RESULTS: **
This article describes the content, rationale, and evidence for 11 recommendations. Key treatment principles include considering psychosocial interventions, such as evidence-based parent and child skills training as the first line of treatment; targeting the underlying disorder first following evidence-based guidelines; considering individual psychosocial and medical factors, including cardiovascular risk in the selection of agents if medication treatment (ideally with the best evidence base) is initiated; avoiding the use of multiple psychotropic medications simultaneously; and careful monitoring of treatment response, by using structured rating scales, as well as close medical monitoring for side effects, including metabolic changes. 

**CONCLUSIONS:** 
Treatment of children with maladaptive aggression is a &quot;moving target&quot; requiring ongoing assimilation of new evidence as it emerges. Based on the existing evidence, the Treatment of Maladaptive Aggression in Youth guidelines provide a framework for management of maladaptive aggression in youth, appropriate for use by primary care clinicians and mental health providers. 

Pediatrics 2012;129:e1577-e1586
AD  - [Jensen, Peter S.] Mayo Clin, Dept Psychiat &amp; Psychol, Rochester, MN 55905 USA. [Rosato, Nancy Scotto] Dept Hlth &amp; Senior Serv, Trenton, NJ USA. [Correll, Christoph U.] Zucker Hillside Hosp, Long Isl City, NY USA. [Pappadopulos, Elizabeth] Pfizer Inc, Div Continuing Educ, New York, NY USA. [Chait, Alanna; Jensen, Peter S.] REACH Inst, New York, NY USA. [Crystal, Stephen] Rutgers State Univ, Ctr Educ &amp; Res Mental Hlth Therapeut, New Brunswick, NJ 08903 USA. Jensen, PS (reprint author), Mayo Clin, Dept Psychiat &amp; Psychol, 200 1st St SW, Rochester, MN 55905 USA. peterjensen@thereachinstitute.org
AN  - WOS:000304707000025
AU  - Rosato,
AU  - N.
AU  - S.
AU  - Correll,
AU  - C.
AU  - U.
AU  - Pappadopulos,
AU  - E.
AU  - Chait,
AU  - A.
AU  - Crystal,
AU  - S.
AU  - Jensen,
AU  - P.
AU  - S.
AU  - Treatment
AU  - of
AU  - Maladaptive
AU  - Aggressive
AU  - in
AU  - Youth
AU  - Steering
AU  - Committee
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2010-1361
J2  - Pediatrics
KW  - aggression psychosocial intervention psychotropic drugs guidelines behavior disorders problems RANDOMIZED CLINICAL-TRIAL COPING POWER PROGRAM ATTENTION-DEFICIT/HYPERACTIVITY DISORDER CHILD INTERACTION THERAPY 1-YEAR FOLLOW-UP DISRUPTIVE BEHAVIOR ANTIPSY
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 951FT Times Cited: 11 Cited Reference Count: 61 Rosato, Nancy Scotto Correll, Christoph U. Pappadopulos, Elizabeth Chait, Alanna Crystal, Stephen Jensen, Peter S. Correll, Christoph/D-3530-2011 Agency for Healthcare Research and Quality [U18-HS016097]; REACH Institute; Annie E. Casey Foundation; Texas Department of State Health Services; State of New York This work was supported through Agency for Healthcare Research and Quality cooperative agreement U18-HS016097, for the Center for Education and Research on Mental Health Therapeutics (Dr Crystal), with additional support from the REACH Institute, the Annie E. Casey Foundation, the Texas Department of State Health Services, and the State of New York. 11 AMER ACAD PEDIATRICS ELK GROVE VILLAGE PEDIATRICS
PY  - 2012
SP  - E1577-E1586
T2  - Pediatrics
TI  - Treatment of Maladaptive Aggression in Youth: CERT Guidelines II. Treatments and Ongoing Management
UR  - &lt;Go to ISI&gt;://WOS:000304707000025http://pediatrics.aappublications.org/content/129/6/e1577.full.pdf
VL  - 129
ER  -
TY  - JOUR
AB  - **Objectives: **
To evaluate the impact of school-based mentoring for adolescents (11-18 years) on academic performance, attendance, attitudes, behavior, and self-esteem. 

**Method:** 
A systematic review and meta-analysis. The authors searched 12 databases from 1980 to 2011. Eight studies with 6,072 participants were included, 6 were included in meta-analysis. Studies were assessed using the Cochrane Collaboration Risk of Bias Tool. 

**Results: **
Across outcomes, effect sizes were very small (random effects), and most were not significant. The magnitude of the largest effect (for self-esteem) was close to zero, g = 0.09, [0.03, 0.14]. 

**Conclusions: **
The mentoring programs included in this review did not reliably improve any of the included outcomes. Well-designed programs implemented over a longer time might achieve positive results. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - Mayo-Wilson, Evan: evan.mayo-wilson@ucl.ac.uk Mayo-Wilson, Evan: National Collaborating Centre for Mental Health, Centre for Outcomes Research and Effectiveness, Research Department of Clinical, Educational &amp; Health Psychology, University College London, 1-19 Torrington Place, London, United Kingdom, WC1E 7HB, evan.mayo-wilson@ucl.ac.uk Wood, Sarah: Centre for Evidence-Based Intervention, Department of Social Policy and Intervention, University of Oxford, London, United Kingdom Mayo-Wilson, Evan: Centre for Evidence-Based Intervention, Department of Social Policy and Intervention, University of Oxford, London, United Kingdom
AN  - 2012-09652-001
AU  - Wood,
AU  - S.
AU  - Mayo-Wilson,
AU  - E.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1049731511430836
DP  - Ovid Technologies
KW  - school-based mentoring, adolescent development, academic performance, attendance *Academic Achievement *Adolescent Development *Mentor *Performance *School Attendance Academic Learning &amp; Achievement [3550] Human
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2012
SP  - 257-269
T2  - Research on Social Work Practice
TI  - School-based mentoring for adolescents: A systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc9&amp;AN=2012-09652-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1049731511430836&amp;issn=1049-7315&amp;isbn=&amp;volume=22&amp;issue=3&amp;spage=257&amp;pages=257-269&amp;date=2012&amp;title=Research+on+Social+Work+Practice&amp;atitle=School-based+mentoring+for+adolescents%3A+A+systematic+review+and+meta-analysis.&amp;aulast=Wood&amp;pid=%3Cauthor%3EWood%2C+Sarah%3C%2Fauthor%3E%3CAN%3E2012-09652-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rsw.sagepub.com/content/22/3/257http://rsw.sagepub.com/content/22/3/257.full.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - **Aims  **
To identify and assess the effectiveness of experimental studies of interventions that report on multiple risk behaviour outcomes in young people. 

**Methods  **
A systematic review was performed to identify experimental studies of interventions to reduce risk behaviour in adolescents or young adults and that reported on both any substance (alcohol, tobacco and illicit drug) use and sexual risk behaviour outcomes. Two authors reviewed studies independently identified through a comprehensive search strategy and assessed the quality of included studies. The report was prepared in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. 

**Results  **
From 1129 papers, 18 experimental studies met our inclusion criteria, 13 of which were assigned a strong or moderate quality rating. The substantial heterogeneity between studies precluded the pooling of results to give summary estimates. Intervention effects were mixed, with most programmes having a significant effect on some outcomes, but not others. The most promising interventions addressed multiple domains (individual and peer, family, school and community) of risk and protective factors for risk behaviour. Programmes that addressed just one domain were generally less effective in preventing multiple risk behaviour. 

**Conclusions **
There is some, albeit limited, evidence that programmes to reduce multiple risk behaviours in school children can be effective, the most promising programmes being those that address multiple domains of influence on risk behaviour. Intervening in the mid-childhood school years may have an impact on later risk behaviour, but further research is needed to determine the effectiveness of this approach.
AD  - [Jackson, Caroline; Geddes, Rosemary; Haw, Sally; Frank, John] Western Gen Hosp, Scottish Collaborat Publ Hlth Res &amp; Policy, MRC Human Genet Unit Bldg, Edinburgh EH4 2XU, Midlothian, Scotland. [Haw, Sally] Univ Stirling, Ctr Publ Hlth &amp; Populat Hlth Res, Sch Nursing Midwifery &amp; Hlth, Stirling FK9 4LA, Scotland. [Frank, John] Univ Edinburgh, Sch Med, Ctr Populat Hlth Sci, Edinburgh, Midlothian, Scotland. Jackson, C (reprint author), Western Gen Hosp, Scottish Collaborat Publ Hlth Res &amp; Policy, MRC Human Genet Unit Bldg, Crewe Rd S, Edinburgh EH4 2XU, Midlothian, Scotland. caroline.jackson@hgu.mrc.ac.uk
AN  - WOS:000300832100007
AU  - Jackson,
AU  - C.
AU  - Geddes,
AU  - R.
AU  - Haw,
AU  - S.
AU  - Frank,
AU  - J.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1360-0443.2011.03751.x
J2  - Addiction
KW  - Adolescence complex interventions multiple risk behaviour sexual behaviour substance use systematic review SOCIAL-DEVELOPMENT INTERVENTION RANDOMIZED CONTROLLED-TRIAL AFRICAN-AMERICAN YOUTH ADOLESCENT DRUG-USE SOUTH-AFRICA HIV-INFECTION PROGRAM HEALTH A
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 899QV Times Cited: 12 Cited Reference Count: 58 Jackson, Caroline Geddes, Rosemary Haw, Sally Frank, John Price, Katie/H-1931-2012 Scottish Collaboration for Public Health Research and Policy; Medical Research Council; Scottish Government Chief Scientist Office The review was carried out under the auspices of the Scottish Collaboration for Public Health Research and Policy, which is co-funded by the Medical Research Council and the Scottish Government Chief Scientist Office. The funders played no role in the design of the review, the collection, analysis and interpretation of study data, the writing of the report or the decision to submit the paper for publication. 12 WILEY-BLACKWELL HOBOKEN ADDICTION
PY  - 2012
SP  - 733-747
T2  - Addiction
TI  - Interventions to prevent substance use and risky sexual behaviour in young people: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000300832100007http://onlinelibrary.wiley.com/store/10.1111/j.1360-0443.2011.03751.x/asset/j.1360-0443.2011.03751.x.pdf?v=1&amp;t=ib3l00ww&amp;s=d80f2d82e8ff225ee32174aa995694395db639e4
UR  - http://onlinelibrary.wiley.com/doi/10.1111/j.1360-0443.2011.03751.x/abstract
VL  - 107
ER  -
TY  - JOUR
AB  - **Background:** 
Depressive disorders often begin during childhood or adolescence. There is a growing body of evidence supporting effective treatments during the acute phase of a depressive disorder. However, little is known about treatments for preventing relapse or recurrence of depression once an individual has achieved remission or recovery from their symptoms.

**Objectives:** 
To determine the efficacy of early interventions, including psychological and pharmacological interventions, to prevent relapse or recurrence of depressive disorders in children and adolescents.

**Search methods:** 
We searched the Cochrane Depression, Anxiety and Neurosis Review Group&#039;s Specialised Register (CCDANCTR) (to 1 June 2011). The CCDANCTR contains reports of relevant randomised controlled trials from The Cochrane Library (all years), EMBASE (1974 to date), MEDLINE (1950 to date) and PsycINFO (1967 to date). In addition we handsearched the references of all included studies and review articles.

**Selection criteria:** 
Randomised controlled trials using a psychological or pharmacological intervention, with the aim of preventing relapse or recurrence from an episode of major depressive disorder (MDD) or dysthymic disorder (DD) in children and adolescents were included. Participants were required to have been diagnosed with MDD or DD according to DSM or ICD criteria, using a standardised and validated assessment tool.

**Data collection and analysis:** 
Two review authors independently assessed all trials for inclusion in the review, extracted trial and outcome data, and assessed trial quality. Results for dichotomous outcomes are expressed as odds ratio and continuous measures as mean difference or standardised mean difference. We combined results using random-effects meta-analyses, with 95% confidence intervals. We contacted lead authors of included trials and requested additional data where possible.

**Main results:** 
Nine trials with 882 participants were included in the review. In five trials the outcome assessors were blind to the participants&#039; intervention condition and in the remainder of trials it was unclear. In the majority of trials, participants were either not blind to their intervention condition, or it was unclear whether they were or not. Allocation concealment was also unclear in the majority of trials. Although all trials treated participants in an outpatient setting, the designs implemented in trials was diverse, which limits the generalisability of the results. Three trials indicated participants treated with antidepressant medication had lower relapse-recurrence rates (40.9%) compared to those treated with placebo (66.6%) during a relapse prevention phase (odds ratio (OR) 0.34; 95% confidence interval (CI) 0.18 to 0.64, P = 0.02). One trial that compared a combination of psychological therapy and medication to medication alone favoured a combination approach over medication alone, however this result did not reach statistical significance (OR 0.26; 95% CI 0.06 to 1.15). The majority of trials that involved antidepressant medication reported adverse events including suicide-related behaviours. However, there were not enough data to show which treatment approach results in the most favourable adverse event profile.

**Authors&#039; conclusions:** 
Currently, there is little evidence to conclude which type of treatment approach is most effective in preventing relapse or recurrence of depressive episodes in children and adolescents. Limited trials found that antidepressant medication reduces the chance of relapse-recurrence in the future, however, there is considerable diversity in the design of trials, making it difficult to compare outcomes across studies. Some of the research involving psychological therapies is encouraging, however at present more trials with larger sample sizes need to be conducted in order to explore this treatment approach further.
AN  - CD007504
AU  - Cox,
AU  - G.
AU  - R.
AU  - Fisher,
AU  - C.
AU  - A.
AU  - De
AU  - Silva,
AU  - S.
AU  - Phelan,
AU  - M.
AU  - Akinwale,
AU  - O.
AU  - P.
AU  - Simmons,
AU  - M.
AU  - B.
AU  - Hetrick,
AU  - S.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007504.pub2
KW  - Antidepressive Agents [therapeutic use]
KW  - Depressive Disorder [prevention &amp; control]
KW  - Psychotherapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Secondary Prevention
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for preventing relapse and recurrence of a depressive disorder in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007504.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007504.pub2/asset/CD007504.pdf?v=1&amp;t=iw7jurdx&amp;s=ee76f3e8a93d318cd26f4f027a113d1233eb5dd6
ER  -
TY  - JOUR
AB  - **Aim:**
 The purpose of this systematic review was to examine research utilizing single subject research designs (SSRD) to explore the effectiveness of interventions designed to increase parents&#039; ability to support communication and social development in children with autism spectrum disorders (ASDs). 

**Method:**
Included studies were systematically assessed for methodological quality (Logan et al., 2008; Smith et al., 2007) and intervention effects. Data examining participant characteristics, study methodology, outcomes, and analysis were systematically extracted. 

**Results:**
Eleven SSRD parent-training intervention studies examining 44 participants with ASD were included. Overall, the studies were of moderate quality and reported increases in parent skills and child language and communication outcomes. 

**Interpretation:**
The results supported by improvement rate difference (IRD) analysis indicated several interventions demonstrated positive effects for both parent and child outcomes. However, limited generalization and follow-up data suggested only one intervention demonstrated parents&#039; accurate and ongoing intervention implementation beyond training.
AD  - [Patterson, Stephanie Y.] Univ Calif Los Angeles, Grad Sch Educ &amp; Informat Studies, Los Angeles, CA 90095 USA. [Smith, Veronica] Univ Alberta, Edmonton, AB T6G 2M7, Canada. [Mirenda, Pat] Univ British Columbia, Vancouver, BC V5Z 1M9, Canada. Patterson, SY (reprint author), Univ Calif Los Angeles, Grad Sch Educ &amp; Informat Studies, Moore Hall 2027,Box 951521, Los Angeles, CA 90095 USA. sypatterson@ucla.edu
AN  - WOS:000309352600005
AU  - Patterson,
AU  - S.
AU  - Y.
AU  - Smith,
AU  - V.
AU  - Mirenda,
AU  - P.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1362361311413398
J2  - Autism
KW  - autism intervention parent training communication single subject research design YOUNG-CHILDREN SOCIAL-INTERACTION EARLY INTERVENTION PRESCHOOL SKILLS TRIAL COMMUNICATION EDUCATION PARADIGM FAMILIES Psychology, Developmental
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 014CL Times Cited: 7 Cited Reference Count: 53 Patterson, Stephanie Y. Smith, Veronica Mirenda, Pat 8 SAGE PUBLICATIONS LTD LONDON AUTISM
PY  - 2012
SP  - 498-522
T2  - Autism
TI  - A systematic review of training programs for parents of children with autism spectrum disorders: Single subject contributions
UR  - &lt;Go to ISI&gt;://WOS:000309352600005http://aut.sagepub.com/content/16/5/498http://aut.sagepub.com/content/16/5/498.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/1362361311413398?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 16
ER  -
TY  - JOUR
AB  - The aims of the present study were, first, to establish the effect of brief, in-home intensive family preservation programs on prevention of out-of-home placement, family functioning, child behavior problems and social support and, second, to study moderators of these effects. 

The results of this meta-analytic study, consisting of 20 studies (31,369 participants), show that intensive family preservation programs had a medium and positive effect on family functioning (d = .486), but were generally not effective in preventing out-of-home placement. Intensive family preservation programs were effective in preventing placement for multi-problem families, but not for families experiencing abuse and neglect. 

Moreover, the effect on out-of-home placement proved to be moderated by client characteristics (sex and age of the child, parent age, number of children in the family, single-parenthood, non-white ethnicity), program characteristics (caseload),study characteristics (study design and study quality), and publication characteristics (publication type, publication year and journal impact factor). 

The discussion addresses implications for evaluation and practice. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - W M Al, Channa M. W.: channa@augeo-foundation.nl; Stams, Geert Jan J. M.: G.J.J.M.Stams@uva.nl; Bek, Miranda S.: mirandabek@gmail.com; Damen, Esther M.: esther.damen@opvoedpoli.nl; van der Laan, Peter H.: PvanderLaan@nscr.nl Al, Channa M. W.: University of Amsterdam, Faculty of Social and Behavioral Sciences, Department of Forensic Child and Youth Care Sciences, P.O. Box 94208, Amsterdam, Netherlands, 1090 GE, channa@augeo-foundation.nl Al, Channa M. W.: University of Amsterdam, Faculty of Social and Behavioral Sciences, Department of Forensic Child and Youth Care Sciences, Amsterdam, Netherlands Stams, Geert Jan J. M.: University of Amsterdam, Faculty of Social and Behavioral Sciences, Department of Forensic Child and Youth Care Sciences, Amsterdam, Netherlands Damen, Esther M.: Opvoedpoli, Haarlem, Netherlands Asscher, Jessica J.: University of Amsterdam, Faculty of Social and Behavioral Sciences, Department of Forensic Child and Youth Care Sciences, Amsterdam, Netherlands van der Laan, Peter H.: Netherlands Institute for the Study of Crime and Law Enforcement (NWO-NSCR), Amsterdam, Netherlands
AN  - 2012-12752-001
AU  - Channa,
AU  - A.
AU  - M.
AU  - Geert,
AU  - J.
AU  - Stams,
AU  - M.
AU  - J.
AU  - Bek,
AU  - E.
AU  - S.
AU  - Damen,
AU  - J.
AU  - M.
AU  - Asscher,
AU  - J.
AU  - van
AU  - der
AU  - Laan,
AU  - P.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2012.04.002
DP  - Ovid Technologies
KW  - family preservation programs, family functioning, child behavior problems, social support, prevention of out-of-home placement *Behavior Problems *Family Intervention *Family Preservation *Family Relations *Social Support Child Welfare Prevention Commun
L1  - internal-pdf://2731544091/Channa-2012-A meta-analysis of intensive famil.pdf
LA  - English
M3  - Meta Analysis
PY  - 2012
SP  - 1472-1479
T2  - Children and Youth Services Review
TI  - A meta-analysis of intensive family preservation programs: Placement prevention and improvement of family functioning
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc9&amp;AN=2012-12752-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2012.04.002&amp;issn=0190-7409&amp;isbn=&amp;volume=34&amp;issue=8&amp;spage=1472&amp;pages=1472-1479&amp;date=2012&amp;title=Children+and+Youth+Services+Review&amp;atitle=A+meta-analysis+of+intensive+family+preservation+programs%3A+Placement+prevention+and+improvement+of+family+functioning.&amp;aulast=Al&amp;pid=%3Cauthor%3EAl%2C+Channa+M.+W%3C%2Fauthor%3E%3CAN%3E2012-12752-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0190740912001600/1-s2.0-S0190740912001600-main.pdf?_tid=0210a65c-18cd-11e5-bfba-00000aacb361&amp;acdnat=1434970628_97eac09cc2b0b8db09f4c7f0f38e4aa9
VL  - 34
ER  -
TY  - JOUR
AB  - This study assessed the effectiveness of culturally sensitive interventions (CSIs) (IV = 10) designed to address substance use among minority youths. 

Study methods consisted of systematic search procedures, quality of study ratings, and meta-analytic techniques to gauge effects and evaluate publication bias. 

The results, across all measures and time frames, reveal small effects (Hedges&#039;s g = .118, 95% confidence interval [CI] = 0.004 to 0.232). For recent alcohol use, the effects were small (Hedges&#039;s g = .225, 95% CI = 0.015 to 0.435). For recent marijuana use, the effects failed to achieve significance (Hedges&#039;s g = .610, 95%) CI = -0.256 to 1.476). 

Suggestions for enhancing the effectiveness of CSIs are discussed along with the benefits and limitations of using meta-analyses versus narrative reviews to assess intervention effectiveness in emerging areas of research. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Hodge, David R.: School of Social Work, Arizona State University, Mail Code 3920, 411 K. Central, Suite 800, Phoenix, AZ, US, 85004-0689 Hodge, David R.: School of Social Work, Arizona State University, Phoenix, AZ, US Jackson, Kelly F.: Southwest Interdisciplinary Research Center, School of Social Work, Arizona State University, Phoenix, AZ, US Vaughn, Michael G.: School of Social Work, Saint Louis University, MO, US
AN  - 2012-22029-003
AU  - Hodge,
AU  - D.
AU  - R.
AU  - Jackson,
AU  - K.
AU  - F.
AU  - Vaughn,
AU  - M.
AU  - G.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1093/swr/svs008
DP  - Ovid Technologies
KW  - culturally sensitive interventions, substance usage, alcohol drinking *Alcohol Drinking Patterns *Cultural Sensitivity *Drug Usage *Intervention Drug &amp; Alcohol Rehabilitation [3383] Human
LA  - English
M3  - Meta Analysis
PY  - 2012
SP  - 11-19
T2  - Social Work Research
TI  - Culturally sensitive interventions and substance use: A meta-analytic review of outcomes among minority youths
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc9&amp;AN=2012-22029-003 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1093%2Fswr%2Fsvs008&amp;issn=1070-5309&amp;isbn=&amp;volume=36&amp;issue=1&amp;spage=11&amp;pages=11-19&amp;date=2012&amp;title=Social+Work+Research&amp;atitle=Culturally+sensitive+interventions+and+substance+use%3A+A+meta-analytic+review+of+outcomes+among+minority+youths.&amp;aulast=Hodge&amp;pid=%3Cauthor%3EHodge%2C+David+R%3C%2Fauthor%3E%3CAN%3E2012-22029-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://swr.oxfordjournals.org/content/36/1/11http://swr.oxfordjournals.org/content/36/1/11.full.pdf
VL  - 36
ER  -
TY  - JOUR
AB  - Many individuals with autism cannot speak or cannot speak intelligibly. 

A variety of aided augmentative and alternative communication (AAC) approaches have been investigated. Most of the research on these approaches has been single-case research, with small numbers of participants. 

The purpose of this investigation was to meta-analyze the single case research on the use of aided AAC with individuals with autism spectrum disorders (ASD). 

Twenty-four single-case studies were analyzed via an effect size measure, the Improvement Rate Difference (IRD). Three research questions were investigated concerning the overall impact of AAC interventions on targeted behavioral outcomes, effects of AAC interventions on individual targeted behavioral outcomes, and effects of three types of AAC interventions. 

Results indicated that, overall, aided AAC interventions had large effects on targeted behavioral outcomes in individuals with ASD. AAC interventions had positive effects on all of the targeted behavioral outcome; however, effects were greater for communication skills than other categories of skills. 

Effects of the Picture Exchange Communication System and speech-generating devices were larger than those for other picture-based systems, though picture-based systems did have small effects.
AD  - Ganz,Jennifer B. Texas A&amp;M University, College Station, TX, USA. jeniganz@tamu.edu
AN  - 21380612
AU  - Ganz,
AU  - J.
AU  - B.
AU  - Earles-Vollrath,
AU  - T.
AU  - L.
AU  - Heath,
AU  - A.
AU  - K.
AU  - Parker,
AU  - R.
AU  - I.
AU  - Rispoli,
AU  - M.
AU  - J.
AU  - Duran,
AU  - J.
AU  - B.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10803-011-1212-2
DP  - Ovid Technologies
J2  - J Autism Dev Disord
KW  - Child *Child Development Disorders, Pervasive/px [Psychology] *Communication *Communication Aids for Disabled Humans
L1  - internal-pdf://1267425429/Ganz-2012-A meta-analysis of single case resea.pdf
LA  - English
M3  - Meta-Analysis
N1  - Ganz, Jennifer B Earles-Vollrath, Theresa L Heath, Amy K Parker, Richard I Rispoli, Mandy J Duran, Jaime B
PY  - 2012
SP  - 60-74
T2  - Journal of Autism and Developmental Disorders
TI  - A meta-analysis of single case research studies on aided augmentative and alternative communication systems with individuals with autism spectrum disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21380612 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21380612&amp;id=doi:10.1007%2Fs10803-011-1212-2&amp;issn=0162-3257&amp;isbn=&amp;volume=42&amp;issue=1&amp;spage=60&amp;pages=60-74&amp;date=2012&amp;title=Journal+of+Autism+%26+Developmental+Disorders&amp;atitle=A+meta-analysis+of+single+case+research+studies+on+aided+augmentative+and+alternative+communication+systems+with+individuals+with+autism+spectrum+disorders.&amp;aulast=Ganz&amp;pid=%3Cauthor%3EGanz+JB%3C%2Fauthor%3E%3CAN%3E21380612%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10803-011-1212-2
UR  - http://oaktrust.library.tamu.edu/bitstream/handle/1969.1/152916/AAC%20meta%2007-13-10%20JADD%2010%2033R2.pdf?sequence=1
VL  - 42
ER  -
TY  - JOUR
AB  - Recently emerging intervention studies for toddlers with autism spectrum disorders (ASD) were reviewed through a systematic assessment of intervention outcomes, research rigor, and intervention features. The review includes published peer-reviewed experimental studies of toddlers with high risk for or diagnosis of ASD in which the majority of interventions occurred before age 36 months. Of 20 identified research studies, 6 were group comparison studies, all of which showed small to large magnitudes of effect when a uniform metric was applied. Fourteen were single-case design (SCD) studies, all of which reported effects on a variety of outcomes. When grouped by area of intervention focus (communication, general development, family well-being, imitation, joint attention, and play), commonly identified needs within focus areas were for replication, common measures, and authentic practices. A majority of studies in most focus areas showed strong to acceptable levels of research rigor, though this is an area of ongoing need.
AD  - [Schertz, Hannah H.] Indiana Univ, Sch Educ, Dept Curriculum &amp; Instruct, Bloomington, IN 47405 USA. [Reichow, Brian] Yale Univ, Ctr Child Study, New Haven, CT 06520 USA. Schertz, HH (reprint author), Indiana Univ, Sch Educ, Dept Curriculum &amp; Instruct, 201 N Rose Ave, Bloomington, IN 47405 USA. hschertz@indiana.edu
AN  - WOS:000312777700003
AU  - Schertz,
AU  - H.
AU  - H.
AU  - Reichow,
AU  - B.
AU  - Tan,
AU  - P.
AU  - Vaiouli,
AU  - P.
AU  - Yildirim,
AU  - E.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1053815112470721
J2  - J. Early Interv.
KW  - autism spectrum disorders disabilities and development delays Part C services components of practice infants and toddlers young children instruction PERVASIVE DEVELOPMENTAL DISORDERS RANDOMIZED CONTROLLED-TRIAL JOINT ATTENTION YOUNG-CHILDREN SPECIAL-EDU
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 060KW Times Cited: 3 Cited Reference Count: 99 Schertz, Hannah H. Reichow, Brian Tan, Paulo Vaiouli, Potheini Yildirim, Emine 3 COUNCIL EXCEPTIONAL CHILDREN ARLINGTON J EARLY INTERVENTION
PY  - 2012
SP  - 166-189
T2  - Journal of Early Intervention
TI  - Interventions for Toddlers With Autism Spectrum Disorders: An Evaluation of Research Evidence
UR  - &lt;Go to ISI&gt;://WOS:000312777700003http://jei.sagepub.com/content/34/3/166http://jei.sagepub.com/content/34/3/166.full.pdf
VL  - 34
ER  -
TY  - JOUR
AB  - **Background **
Tobacco use in Indigenous populations (people who have inhabited a country for thousands of years) is often double that in the non-Indigenous population. Addiction to nicotine usually begins during early adolescence and young people who reach the age of 18 as non-smokers are unlikely to become smokers thereafter. Indigenous youth in particular commence smoking at an early age, and a disproportionate burden of substance-related morbidity and mortality exists as a result. 

**Objectives **
To evaluate the effectiveness of intervention programmes to prevent tobacco use initiation or progression to regular smoking amongst young Indigenous populations and to summarise these approaches for future prevention programmes and research. 

**Search methods **
The Cochrane Tobacco Addiction Group Specialised Register was searched in November 2011, with additional searches run in MEDLINE. Online clinical trial databases and publication references were also searched for potential studies.

**Selection criteria **
We included randomized and non-randomized controlled trials aiming to prevent tobacco use initiation or progression from experimentation to regular tobacco use in Indigenous youth. Interventions could include school-based initiatives, mass media, multi-component community level interventions, family-based programmes or public policy. 

**Data collection and analysis **
Data pertaining to methodology, participants, interventions and outcomes were extracted by one reviewer and checked by a second, whilst information on risk of bias was extracted independently by a combination of two reviewers. Studies were assessed by qualitative narrative synthesis, as insufficient data were available to conduct a meta-analysis. The review process was examined by an Indigenous (Aboriginal) Australian for applicability, acceptability and content.

**Main results **
Two studies met all of the eligibility criteria for inclusion within the review and a third was identified as ongoing. The two included studies employed multi-component community-based interventions tailored to the specific cultural aspects of the population and were based in Native American populations (1505 subjects in total). No difference was observed in weekly smoking at 42 months follow-up in the one study assessing this outcome (skills-community group versus control: risk ratio [RR] 0.95, 95% CI 0.78 to 1.14; skills-only group versus control: RR 0.86, 95% CI 0.71 to 1.05). For smokeless tobacco use, no difference was found between the skills-community arm and the control group at 42 weeks (RR 0.93, 95% CI 0.67 to 1.30), though a significant difference was observed between the skills-only arm and the control group (RR 0.57, 95% CI 0.39 to 0.85). Whilst the second study found positive changes for tobacco use in the intervention arm at post test (p &lt; 0.05), this was not maintained at six month follow-up (change score -0.11 for intervention and 0.07 for control). Both studies were rated as high or unclear risk of bias in seven or more domains (out of a total of 10). 

**Authors&#039; conclusions **
Based on the available evidence, a conclusion cannot be drawn as to the efficacy of tobacco prevention initiatives tailored for Indigenous youth. This review highlights the paucity of data and the need for more research in this area. Smoking prevalence in Indigenous youth is twice that of the non-Indigenous population, with tobacco experimentation commencing at an early age. As such, a significant health disparity exists where Indigenous populations, a minority, are over-represented in the burden of smoking-related morbidity and mortality. Methodologically rigorous trials are needed to investigate interventions aimed at preventing the uptake of tobacco use amongst Indigenous youth and to assist in bridging the gap between tobacco-related health disparities in Indigenous and non-Indigenous populations.
AD  - [Carson, Kristin V.; Brinn, Malcolm P.; Labiszewski, Nadina A.] Queen Elizabeth Hosp, Clin Practice Unit, Adelaide, SA 5011, Australia. [Peters, Matthew] Univ Sydney, Concord Clin Sch, Sydney, NSW 2006, Australia. [Chang, Anne B.] Charles Darwin Univ, Menzies Sch Hlth Res, Casuarina, NT, Australia. [Esterman, Adrian J.] Univ S Australia, Adelaide, SA 5001, Australia. [Smith, Brian J.] Univ Adelaide, Dept Med, Queen Elizabeth Hosp, Adelaide, SA 5001, Australia. Carson, KV (reprint author), Queen Elizabeth Hosp, Clin Practice Unit, 4A Main Bldg,28 Woodville Rd, Adelaide, SA 5011, Australia. kristin.carson@health.sa.gov.au
AN  - WOS:000307828900036
AU  - Carson,
AU  - K.
AU  - V.
AU  - Brinn,
AU  - M.
AU  - P.
AU  - Labiszewski,
AU  - N.
AU  - A.
AU  - Peters,
AU  - M.
AU  - Chang,
AU  - A.
AU  - B.
AU  - Veale,
AU  - A.
AU  - Esterman,
AU  - A.
AU  - J.
AU  - Smith,
AU  - B.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009325.pub2
J2  - Cochrane Database Syst Rev.
KW  - NATIVE-AMERICAN YOUTH SMOKING-CESSATION NEW-ZEALAND ADOLESCENT SMOKING CANCER RISK HEALTH-CARE DRUG-USE PEOPLE COMMUNITY PROGRAMS Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 993BK Times Cited: 6 Cited Reference Count: 86 Carson, Kristin V. Brinn, Malcolm P. Labiszewski, Nadina A. Peters, Matthew Chang, Anne B. Veale, Antony Esterman, Adrian J. Smith, Brian J. Chang, Anne/F-2066-2013; Esterman, Adrian/D-1042-2009 GSK; Respirator Medicine Unit, The Queen Elizabeth Hospital, Australia; University of Adelaide, Australia ABC has received a grant provided by GSK which is unrelated to this topic. She is also the principal investigator on a study examining azithromycin for bronchiolitis in Indigenous children. MJP has received honoria in relation to attendance at a Smoking Cessation Advisory Board from Pfizer Ltd. No other conflicts of interest are known.Internal sourcesRespirator Medicine Unit, The Queen Elizabeth Hospital, Australia.The University of Adelaide, Australia. 6 WILEY-BLACKWELL HOBOKEN COCHRANE DB SYST REV
PY  - 2012
SP  - 34
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for tobacco use prevention in Indigenous youth
UR  - &lt;Go to ISI&gt;://WOS:000307828900036http://onlinelibrary.wiley.com/store/10.1002/14651858.CD009325.pub2/asset/CD009325.pdf?v=1&amp;t=ib7t4u2f&amp;s=66aa6175ff3f8de7bab50125dcfb426abc60eda9
ER  -
TY  - JOUR
AB  - Increasingly more educational centres are, therefore, carrying out programmes aimed at preventing or reducing violence in schools. This study seeks to examine the efficiency of such programmes in Primary and Secondary schools. The methodology used is the systematic search of electronic databases (Medline, Trip Database, Cochrane, Academy Search Premier, PsycINFO, ERIC and PsycARTICLES) for studies published after January 1, 2000, on the assessment of the effectiveness of school interventions to prevent or reduce violence and bullying. The study population comprises school-age (6-16 years) children and adolescents of both sexes. Initially, 299 articles were detected that met the inclusion criteria and that had been independently peer-reviewed. For the final evaluation, 32 studies were selected which met the previously established selection and quality criteria, and analysed by level of evidence. The review finds evidence of the efficiency of the programmes assessed, although serious limitations are also detected, which should be taken into consideration when designing future interventions. The likelihood of success is enhanced when all the disciplines of a centre are involved, and also the parents. It is also essential to adapt the diverse programmes to the social and cultural characteristics of the school population in which the programme is to be carried out. Finally, the findings indicate the need for continuity in the programmes if their long-term efficiency is to be guaranteed. (C) 2012 Elsevier Ltd. All rights reserved.
AD  - [Jimenez Barbero, Jose Antonio; Ruiz Hernandez, Jose Antonio; Llor Esteban, Bartolome] Univ Murcia, Fac Pshychol, E-30100 Murcia, Spain. [Perez Garcia, Maria] Univ Murcia, Fac Med, E-30100 Murcia, Spain. Barbero, JAJ (reprint author), Plaza Vistabella 17,2L, Murcia 30820, Spain. barbero49@hotmail.com; jaruiz@um.es; bllor@um.es; mariapg78@hotmail.com
AN  - WOS:000307615700009
AU  - Barbero,
AU  - J.
AU  - A.
AU  - J.
AU  - Hernandez,
AU  - J.
AU  - A.
AU  - R.
AU  - Esteban,
AU  - B.
AU  - L.
AU  - Garcia,
AU  - M.
AU  - P.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2012.04.025
J2  - Child. Youth Serv. Rev.
KW  - Systematic review Intervention programme School violence Prevention Attitudes Effectiveness ANTI-BULLYING INTERVENTION VIOLENCE PREVENTION PROGRAMS CONTROLLED-TRIAL MIDDLE SCHOOLS VICTIMIZATION IMPLEMENTATION BEHAVIOR METAANALYSIS AGGRESSION ATTITUDES F
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 990FF Times Cited: 6 Cited Reference Count: 63 Jimenez Barbero, Jose Antonio Ruiz Hernandez, Jose Antonio Llor Esteban, Bartolome Perez Garcia, Maria 6 PERGAMON-ELSEVIER SCIENCE LTD OXFORD CHILD YOUTH SERV REV
PY  - 2012
SP  - 1646-1658
T2  - Children and Youth Services Review
TI  - Effectiveness of antibullying school programmes: A systematic review by evidence levels
UR  - &lt;Go to ISI&gt;://WOS:000307615700009http://ac.els-cdn.com/S0190740912001831/1-s2.0-S0190740912001831-main.pdf?_tid=faff6bb4-18cc-11e5-920d-00000aacb360&amp;acdnat=1434970616_1d0dd08d507f2549a521129caa015b17
VL  - 34
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
Early-onset child conduct problems are common and costly. A large number of studies and some previous reviews have focused on behavioural and cognitive-behavioural group-based parenting interventions, but methodological limitations are commonplace and evidence for the effectiveness and cost-effectiveness of these programmes has been unclear. 

**OBJECTIVES** 
To assess the effectiveness and cost-effectiveness of behavioural and cognitive-behavioural group-based parenting programmes for improving child conduct problems, parental mental health and parenting skills. SEARCH METHODS We searched the following databases between 23 and 31 January 2011: CENTRAL (2011, Issue 1), MEDLINE (1950 to current), EMBASE (1980 to current), CINAHL (1982 to current), PsycINFO (1872 to current), Social Science Citation Index (1956 to current), ASSIA (1987 to current), ERIC (1966 to current), Sociological Abstracts (1963 to current), Academic Search Premier (1970 to current), Econlit (1969 to current), PEDE (1980 to current), Dissertations and Theses Abstracts (1980 to present), NHS EED (searched 31 January 2011), HEED (searched 31 January 2011), DARE (searched 31 January 2011), HTA (searched 31 January 2011), mRCT (searched 29 January 2011). We searched the following parent training websites on 31 January 2011: Triple P Library, Incredible Years Library and Parent Management Training. We also searched the reference lists of studies and reviews. 

**SELECTION CRITERIA** 
We included studies if: (1) they involved randomised controlled trials (RCTs) or quasi-randomised controlled trials of behavioural and cognitive-behavioural group-based parenting interventions for parents of children aged 3 to 12 years with conduct problems, and (2) incorporated an intervention group versus a waiting list, no treatment or standard treatment control group. We only included studies that used at least one standardised instrument to measure child conduct problems. 

**DATA COLLECTION AND ANALYSIS**
Two authors independently assessed the risk of bias in the trials and the methodological quality of health economic studies. Two authors also independently extracted data. We contacted study authors for additional information. 

**RESULTS** 
This review includes 13 trials (10 RCTs and three quasi-randomised trials), as well as two economic evaluations based on two of the trials. Overall, there were 1078 participants (646 in the intervention group; 432 in the control group). The results indicate that parent training produced a statistically significant reduction in child conduct problems, whether assessed by parents (standardised mean difference (SMD) -0.53; 95% confidence interval (CI) -0.72 to -0.34) or independently assessed (SMD -0.44; 95% CI -0.77 to -0.11). The intervention led to statistically significant improvements in parental mental health (SMD -0.36; 95% CI -0.52 to -0.20) and positive parenting skills, based on both parent reports (SMD -0.53; 95% CI -0.90 to -0.16) and independent reports (SMD -0.47; 95% CI -0.65 to -0.29). Parent training also produced a statistically significant reduction in negative or harsh parenting practices according to both parent reports (SMD -0.77; 95% CI -0.96 to -0.59) and independent assessments (SMD -0.42; 95% CI -0.67 to -0.16). Moreover, the intervention demonstrated evidence of cost-effectiveness. When compared to a waiting list control group, there was a cost of approximately $2500 (GBP 1712; EUR 2217) per family to bring the average child with clinical levels of conduct problems into the non-clinical range. These costs of programme delivery are modest when compared with the long-term health, social, educational and legal costs associated with childhood conduct problems. 

**AUTHORS&rsquo; CONCLUSIONS** 
Behavioural and cognitive-behavioural group-based parenting interventions are effective and cost-effective for improving child conduct problems, parental mental health and parenting skills in the short term. The cost of programme delivery was modest when compared with the long-term health, social, educational and legal costs associated with chi dhood conduct problems. Further research is needed on the long-term assessment of outcomes.
AU  - Furlong,
AU  - M.
AU  - McGilloway,
AU  - S.
AU  - Bywater,
AU  - T.
AU  - Hutchings,
AU  - J.
AU  - Smith,
AU  - S.
AU  - M.
AU  - Donnelly,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2012.12
KW  - Child behaviour
KW  - Parent education
KW  - Parents
PY  - 2012
T2  - Campbell Systematic Reviews
TI  - Behavioural and cognitive-behavioural group-based parenting programmes for early-onset conduct problems in children aged 3 to 12 years
ER  -
TY  - JOUR
AB  - The authors systematically reviewed evidence on iron status, as well as studies of iron supplementation, in individuals with attention deficit/hyperactivity disorder (ADHD). PubMed, Ovid, EMBASE and Web of Knowledge were searched on 4 July 2012. 

Quantitative appraisal of trials was performed using Jadad&#039;s score. Most (n = 20) of the retrieved studies assessed an index of peripheral iron status (i.e., serum ferritin), with overall mixed results - that is, both significant and nonsignificant association between ADHD symptoms and serum ferritin levels. 

One MRI study reported significantly lower indices of thalamic iron in ADHD versus comparison subjects. Two trials, an open-label and a pilot randomized placebo-controlled study with high Jaded score (4), showed improvement in some but not all measures of ADHD symptoms. Three studies showed that children with ADHD plus sleep disorders, in particular restless legs syndrome, are at risk of iron deficiency. 

Finally, two studies suggested that iron deficiency might decrease the effectiveness of psychostimulant treatment. The authors discussed how the field could move from initial research mainly focused on serum ferritin towards a more comprehensive and translational investigation of iron in ADHD, with the potential to inform clinical practice in terms of screening and treating iron deficiency in individuals with ADHD.
AD  - Cortese,Samuele. Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center of the NYU Langone Medical Center, New York, NY, USA. samuele.cortese@gmail.com
AN  - 23082739
AU  - Cortese,
AU  - S.
AU  - Angriman,
AU  - M.
AU  - Lecendreux,
AU  - M.
AU  - Konofal,
AU  - E.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1586/ern.12.116
DP  - Ovid Technologies
J2  - Expert rev
KW  - Anemia, Iron-Deficiency/dh [Diet Therapy] *Anemia, Iron-Deficiency/pp [Physiopathology] Attention Deficit Disorder with Hyperactivity/bl [Blood] *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] *Attention Deficit Disorder with Hyperactiv
LA  - English
M3  - Meta-Analysis Review
N1  - Cortese, Samuele Angriman, Marco Lecendreux, Michel Konofal, Eric
PY  - 2012
SP  - 1227-40
T2  - Expert Review of Neurotherapeutics
TI  - Iron and attention deficit/hyperactivity disorder: What is the empirical evidence so far? A systematic review of the literature
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=23082739 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23082739&amp;id=doi:10.1586%2Fern.12.116&amp;issn=1473-7175&amp;isbn=&amp;volume=12&amp;issue=10&amp;spage=1227&amp;pages=1227-40&amp;date=2012&amp;title=Expert+Review+of+Neurotherapeutics&amp;atitle=Iron+and+attention+deficit%2Fhyperactivity+disorder%3A+What+is+the+empirical+evidence+so+far%3F+A+systematic+review+of+the+literature.&amp;aulast=Cortese&amp;pid=%3Cauthor%3ECortese+S%3C%2Fauthor%3E%3CAN%3E23082739%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://media.proquest.com/media/pq/classic/doc/2795997731/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Cortese%2C+Samuele%3BAngriman%2C+Marco%3BLecendreux%2C+Michel%3BKonofal%2C+Eric&amp;cit%3Atitle=Iron+and+attention+deficit%2Fhyperactivity+disorder%3A+what+is+the+...&amp;cit%3Apub=Expert+Review+of+Neurotherapeutics&amp;cit%3Avol=12&amp;cit%3Aiss=10&amp;cit%3Apg=1227&amp;cit%3Adate=Oct+2012&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMjEyMjgxNjU5Mjo5OTU1MjQSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNTQ1NzgyCjExMTQ1MDI1MTI6DURvY3VtZW50SW1hZ2VCATBSBk9ubGluZVoCRlRiA1BGVGoKMjAxMi8xMC8wMXIKMjAxMi8xMC8zMXoAggEpUC0xMDAwMjczLTMxMDc1LUNVU1RPTUVSLTEwMDAwMTU3LTExMTUxMTKSAQZPbmxpbmXKAQdFbmROb3Rl0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCKE9TOkVNUy1QZGZEb2NWaWV3QmFzZS1nZXRNZWRpYVVybEZvckl0ZW3KAhZSZXZpZXd8RmVhdHVyZXxBcnRpY2xl0gIBWeICAU7yAgA%3D&amp;_s=dvvCodIeCZ63HH5jfPFei0HIn4I%3D
VL  - 12
ER  -
TY  - JOUR
AB  - Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) is one of the most widely disseminated mental health interventions for children and youth. The purpose of this study is to systematically review the evidence of TF-CBT&#039;s ability to reduce symptoms of post-traumatic stress, depression and behavior problems in children and youth who have survived trauma. 

A search was conducted to locate studies that evaluated TF-CBT or interventions highly similar to TF-CBT. Ten studies (twelve articles) were selected for inclusion in three sets of meta-analyses. 

Findings were consistent amongst meta-analyses; pooled estimates were similar whether we were analyzing the effects of interventions that were highly similar to TF-CBT, or if we were exclusively analyzing the effects of the branded intervention. Results show that there is a significant difference between the TFCBT condition and comparison conditions in its ability to reduce symptoms of PTSD (g=.671), depression (g=.378) and behavior problems (g=.247) immediately after treatment completion. 

This difference held for PTSD at twelve months after treatment completion (.389) but did not hold for depression or behavior problems. There was not a significant difference between the TF-CBT condition and alternative active control conditions immediately after treatment completion. Therefore. TF-CBT is an effective intervention for the treatment of PTSD in youth. 

(C) 2012 Elsevier Ltd. All rights reserved.
AD  - [Cary, Colleen E.; McMillen, J. Curtis] Univ Chicago, Sch Social Serv Adm, Chicago, IL 60637 USA. Cary, CE (reprint author), Univ Chicago, Sch Social Serv Adm, Chicago, IL 60637 USA. cecary@gmail.com
AN  - WOS:000301912600020
AU  - Cary,
AU  - C.
AU  - E.
AU  - McMillen,
AU  - J.
AU  - C.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2012.01.003
J2  - Child. Youth Serv. Rev.
KW  - TF-CBT Post-traumatic stress Depression Behavior problems RANDOMIZED-CONTROLLED-TRIAL POSTTRAUMATIC-STRESS-DISORDER SEXUALLY-ABUSED-CHILDREN SCHOOL-BASED INTERVENTION PTSD SYMPTOMS FOLLOW-UP PRESCHOOL-CHILDREN MULTISYSTEMIC THERAPY ADOLESCENTS CBT Famil
L1  - internal-pdf://4080887265/Cary-2012-The data behind the dissemination_ A.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 913YF Times Cited: 9 Cited Reference Count: 61 Cary, Colleen E. McMillen, J. Curtis 10 PERGAMON-ELSEVIER SCIENCE LTD OXFORD CHILD YOUTH SERV REV
PY  - 2012
SP  - 748-757
T2  - Children and Youth Services Review
TI  - The data behind the dissemination: A systematic review of trauma-focused cognitive behavioral therapy for use with children and youth
UR  - &lt;Go to ISI&gt;://WOS:000301912600020http://ac.els-cdn.com/S0190740912000138/1-s2.0-S0190740912000138-main.pdf?_tid=fd70b9ac-18cc-11e5-b65a-00000aab0f27&amp;acdnat=1434970620_6dff4085d454a40cd2fd4976b09e56ed
VL  - 34
ER  -
TY  - JOUR
AB  - **Background:** 
One potential method of improving outcome for pregnant or postpartum women with a drug or alcohol problem is with home visits.

**Objectives:**
To determine the effects of home visits during pregnancy and/or after birth for women with a drug or alcohol problem.

**Search methods:** 
We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (30 November 2011), CENTRAL (The Cochrane Library 2011, Issue 4 of 4), MEDLINE (1966 to 30 November 2011), EMBASE (1980 to 30 November 2011), CINAHL (1982 to 30 November 2011) and PsycINFO (1974 to 30 November 2011) supplemented by searches of citations from previous reviews and trials and contact with experts.

**Selection criteria:** 
Studies using random or quasi-random allocation of pregnant or postpartum women with a drug or alcohol problem to home visits. Trials enrolling high-risk women of whom more than 50% were reported to use drugs or alcohol were also eligible.

**Data collection and analysis:** 
Review authors performed assessments of trials independently. We performed statistical analyses using fixed-effect and random-effects models where appropriate.

**Main results:** 
Seven studies (reporting 803 mother-infant pairs) compared home visits mostly after birth with no home visits. Visitors included community health nurses, paediatric nurses, trained counsellors, paraprofessional advocates, midwives and lay African-American women. Several studies had significant methodological limitations. There was no significant difference in continued illicit drug use (three studies, 384 women; risk ratio (RR) 1.05, 95% confidence interval (CI) 0.89 to 1.24), continued alcohol use (three studies, 379 women; RR 1.18, 95% CI 0.96 to 1.46), failure to enrol in a drug treatment program (two studies, 211 women; RR 0.45, 95% CI 0.10 to 1.94), not breastfeeding at six months (two studies, 260 infants; RR 0.95, 95% CI 0.83 to 1.10), incomplete six-month infant vaccination schedule (two studies, 260 infants; RR 1.09, 95% CI 0.91 to 1.32), the Bayley Mental Development Index (three studies, 199 infants; mean difference 2.89, 95% CI -1.17 to 6.95) or Psychomotor Index (MD 3.14, 95% CI -0.03 to 6.32), child behavioural problems (RR 0.46, 95% CI 0.21 to 1.01), infants not in care of biological mother (two studies, 254 infants; RR 0.83, 95% CI 0.50 to 1.39), non-accidental injury and non-voluntary foster care (two studies, 254 infants; RR 0.16, 95% CI 0.02 to 1.23) or infant death (three studies, 288 infants; RR 0.70, 95% CI 0.12 to 4.16). Individual studies reported a significant reduction in involvement with child protective services (RR 0.38, 95% CI 0.20 to 0.74) and failure to use postpartum contraception (RR 0.41, 95% CI 0.20 to 0.82).

**Authors&#039; conclusions:** 
There is insufficient evidence to recommend the routine use of home visits for pregnant or postpartum women with a drug or alcohol problem. Further large, high-quality trials are needed.
AN  - CD004456
AU  - Turnbull,
AU  - C.
AU  - Osborn,
AU  - D.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004456.pub2
KW  - House Calls [utilization]
KW  - Postnatal Care
KW  - Pregnancy Complications
KW  - Prenatal Care
KW  - Substance-Related Disorders
KW  - Alcohol-Related Disorders
KW  - Postpartum Period
KW  - Pregnancy Outcome
KW  - Randomized Controlled Trials as Topic
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Infant, Newborn[checkword]
KW  - Pregnancy[checkword]
KW  - Preg
L1  - internal-pdf://4081850455/Turnbull-2012-Home visits during pregnancy and.pdf
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Home visits during pregnancy and after birth for women with an alcohol or drug problem
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004456.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004456.pub3/asset/CD004456.pdf?v=1&amp;t=iw7jnilo&amp;s=50d0a63f35eec80b3fb9533a5b579e9ac2cd72f5
ER  -
TY  - JOUR
AB  - This meta-analysis of 51 studies examines the relationship between various kinds of parental involvement programs and the academic achievement of pre-kindergarten-12th-grade school children. 

Analyses determined the effect sizes for various parental involvement programs overall and subcategories of involvement. 

Results indicate a significant relationship between parental involvement programs overall and academic achievement, both for younger (preelementary and elementary school) and older (secondary school) students as well as for four types of parental involvement programs. 

Parental involvement programs, as a whole, were associated with higher academic achievement by .3 of a standard deviation unit. The significance of these results is discussed. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Jeynes, William: whjharvard@post.harvard.edu Jeynes, William: Department of Education, California State University, 1250 Bellflower Blvd., No. ED2-267, Long Beach, CA, US, 90840, whjharvard@post.harvard.edu Jeynes, William: California State University, Long Beach, CA, US
AN  - 2012-16351-002
AU  - Jeynes,
AU  - W.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0042085912445643
DP  - Ovid Technologies
KW  - parental involvement programs, academic achievement, school children, urban students, program efficacy *Academic Achievement *Educational Program Evaluation *Parent School Relationship *Parental Involvement Elementary School Students Junior High School
LA  - English
M3  - Empirical Study; Meta Analysis; Quantitative Study
PY  - 2012
SP  - 706-742
T2  - Urban Education
TI  - A meta-analysis of the efficacy of different types of parental involvement programs for urban students
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc9&amp;AN=2012-16351-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F0042085912445643&amp;issn=0042-0859&amp;isbn=&amp;volume=47&amp;issue=4&amp;spage=706&amp;pages=706-742&amp;date=2012&amp;title=Urban+Education&amp;atitle=A+meta-analysis+of+the+efficacy+of+different+types+of+parental+involvement+programs+for+urban+students.&amp;aulast=Jeynes&amp;pid=%3Cauthor%3EJeynes%2C+William%3C%2Fauthor%3E%3CAN%3E2012-16351-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://uex.sagepub.com/content/47/4/706http://uex.sagepub.com/content/47/4/706.full.pdf
VL  - 47
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Policymakers need estimates of the impact of tobacco control (TC) policies to set priorities and targets for reducing tobacco use. We systematically reviewed the independent effects of TC policies on smoking behavior. 

**METHODS:**
We searched MEDLINE (through January 2012) and EMBASE and other databases through February 2009, looking for studies published after 1989 in any language that assessed the effects of each TC intervention on smoking prevalence, initiation, cessation, or price participation elasticity. Paired reviewers extracted data from studies that isolated the impact of a single TC intervention. 

**FINDINGS: **
We included 84 studies. The strength of evidence quantifying the independent effect on smoking prevalence was high for increasing tobacco prices and moderate for smoking bans in public places and antitobacco mass media campaigns. Limited direct evidence was available to quantify the effects of health warning labels and bans on advertising and sponsorship. Studies were too heterogeneous to pool effect estimates. 

**INTERPRETATIONS: **
We found evidence of an independent effect for several TC policies on smoking prevalence. However, we could not derive precise estimates of the effects across different settings because of variability in the characteristics of the intervention, level of policy enforcement, and underlying tobacco control environment.
AD  - Wilson,Lisa M. Division of General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. lisawilson@jhmi.edu
AN  - 22719777
AU  - Wilson,
AU  - L.
AU  - M.
AU  - Avila
AU  - Tang,
AU  - E.
AU  - Chander,
AU  - G.
AU  - Hutton,
AU  - H.
AU  - E.
AU  - Odelola,
AU  - O.
AU  - A.
AU  - Elf,
AU  - J.
AU  - L.
AU  - Heckman-Stoddard,
AU  - B.
AU  - M.
AU  - Bass,
AU  - E.
AU  - B.
AU  - Little,
AU  - E.
AU  - A.
AU  - Haberl,
AU  - E.
AU  - B.
AU  - Apelberg,
AU  - B.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1155/2012/961724
DP  - Ovid Technologies
J2  - J Environ Public Health
KW  - Adolescent Adult Advertising as Topic/mt [Methods] Age Factors Aged Child Female Health Promotion/mt [Methods] Humans Male Mass Media Middle Aged Prevalence *Public Policy Smoking/ec [Economics] *Smoking/ep [Epidemiology] Smoking/lj [Legislation &amp; Juris
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Wilson, Lisa M Avila Tang, Erika Chander, Geetanjali Hutton, Heidi E Odelola, Olaide A Elf, Jessica L Heckman-Stoddard, Brandy M Bass, Eric B Little, Emily A Haberl, Elisabeth B Apelberg, Benjamin J
PY  - 2012
SP  - 961724
T2  - Journal Of Environmental &amp; Public Health
TI  - Impact of tobacco control interventions on smoking initiation, cessation, and prevalence: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22719777
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22719777&amp;id=doi:10.1155%2F2012%2F961724&amp;issn=1687-9805&amp;isbn=&amp;volume=2012&amp;issue=&amp;spage=961724&amp;pages=961724&amp;date=2012&amp;title=Journal+Of+Environmental+%26+Public+Health&amp;atitle=Impact+of+tobacco+control+interventions+on+smoking+initiation%2C+cessation%2C+and+prevalence%3A+a+systematic+review.&amp;aulast=Wilson&amp;pid=%3Cauthor%3EWilson+LM%3C%2Fauthor%3E%3CAN%3E22719777%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://downloads.hindawi.com/journals/jeph/2012/961724.pdf
VL  - 2012
ER  -
TY  - JOUR
AB  - Adolescent smoking remains a public health problem. Despite concerns regarding adolescent nicotine dependence, few well-designed smoking cessation studies have been conducted with teen smokers. 
This is particularly true regarding pharmacologic treatments for nicotine dependence. 
Currently, pharmacologic aids are not recommended for treating adolescent nicotine dependence, as efficacy has not been shown in this population. 

This review includes studies that have examined the efficacy of pharmacotherapy for smoking abstinence and/or reduction in cigarette consumption among adolescent smokers who want to quit smoking, laboratory-based adolescent studies that have examined the efficacy of these medications in reducing cravings and/or withdrawal symptoms, and/or studies that have assessed the tolerability of medications for smoking cessation in adolescent smokers. 

It provides information on the pharmacologic action of each medication, the efficacy of each medication for adolescent smoking cessation, the tolerability of each medication based on reported adverse events, and compliance with the medication protocols. 

Thirteen relevant articles were identified and included in the review. Nicotine patch (NP), nicotine gum, nicotine nasal spray, bupropion, and varenicline have been studied in adolescent smokers. 

The adverse events reported in the studies on pharmacology for adolescent smoking suggest that the side effect profiles for nicotine replacement therapy, bupropion, and varenicline are similar to those reported in adult studies. 

There is some evidence of efficacy of NP and bupropion at the end of treatment (efficacy of varenicline has not been assessed), but none of the medications included in this review were efficacious in promoting long-term smoking cessation among adolescent smokers. 

It is noted that many of the study protocols did not follow the recommended dose or length of pharmacotherapy for adults, rendering it difficult to determine the true efficacy of medication for adolescent smoking cessation. 

Future efficacy studies are warranted before recommending pharmacotherapy for adolescent smoking cessation.
AD  - Bailey,Steffani R. Oregon Health Science University, Department of Family Medicine, Portland, OR 97239, USA. bailstef@ohsu.edu
AN  - 22248234
AU  - Bailey,
AU  - S.
AU  - R.
AU  - Crew,
AU  - E.
AU  - E.
AU  - Riske,
AU  - E.
AU  - C.
AU  - Ammerman,
AU  - S.
AU  - Robinson,
AU  - T.
AU  - N.
AU  - Killen,
AU  - J.
AU  - D.
DA  - Apr 1
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319092/
DP  - Ovid Technologies
J2  - Paediatr Drugs
KW  - Adolescent Benzazepines/ad [Administration &amp; Dosage] Benzazepines/ae [Adverse Effects] *Benzazepines/tu [Therapeutic Use] Bupropion/ad [Administration &amp; Dosage] Bupropion/ae [Adverse Effects] *Bupropion/tu [Therapeutic Use] Clinical Trials as Topic Dopa
L1  - internal-pdf://0933395062/Bailey-2012-Efficacy and tolerability of pharm.pdf
LA  - English
M3  - Research Support, N.I.H., Extramural Review
N1  - Bailey, Steffani R Crew, Erin E Riske, Emily C Ammerman, Seth Robinson, Thomas N Killen, Joel D R01 CA 118035 (United States NCI NIH HHS) R01 CA118035 (United States NCI NIH HHS) R01 CA118035-01A1 (United States NCI NIH HHS)
PY  - 2012
SP  - 91-108
T2  - Paediatric Drugs
TI  - Efficacy and tolerability of pharmacotherapies to aid smoking cessation in adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22248234 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22248234&amp;id=doi:10.2165%2F11594370-000000000-00000&amp;issn=1174-5878&amp;isbn=&amp;volume=14&amp;issue=2&amp;spage=91&amp;pages=91-108&amp;date=2012&amp;title=Paediatric+Drugs&amp;atitle=Efficacy+and+tolerability+of+pharmacotherapies+to+aid+smoking+cessation+in+adolescents.&amp;aulast=Bailey&amp;pid=%3Cauthor%3EBailey+SR%3C%2Fauthor%3E%3CAN%3E22248234%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://media.proquest.com/media/pq/classic/doc/2586609461/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Bailey%2C+Steffani+R%3BCrew%2C+Erin+E%3BRiske%2C+Emily+C%3BAmmerman%2C+Seth%3BRobinson%2C+Thomas+N%3BKillen%2C+Joel+D&amp;cit%3Atitle=Efficacy+and+Tolerability+of+Pharmacotherapies+to+Aid+Smoking+Cessation+in+Adolescents&amp;cit%3Apub=Paediatric+Drugs&amp;cit%3Avol=14&amp;cit%3Aiss=2&amp;cit%3Apg=91&amp;cit%3Adate=Apr+2012&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMjA2MzQ0MzIxNDoyODMyNzMSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNDM3MDEyCTkyMTQ1NDk4ODoNRG9jdW1lbnRJbWFnZUIBMFIGT25saW5lWgJGVGIDUEZUagoyMDEyLzA0LzAxcgoyMDEyLzA0LzMwegCCASlQLTEwMDAyNzMtMzEwNzUtQ1VTVE9NRVItMTAwMDAxNTctMTExNTExMpIBBk9ubGluZcoBB0VuZE5vdGXSARJTY2hvbGFybHkgSm91cm5hbHOaAgdQcmVQYWlkqgIoT1M6RU1TLVBkZkRvY1ZpZXdCYXNlLWdldE1lZGlhVXJsRm9ySXRlbcoCFkFydGljbGV8UmV2aWV3fEZlYXR1cmXSAgFZ4gIBTvICAA%3D%3D&amp;_s=6dD0OVVw6j3tHWN3JavVdkHCCWY%3D
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319092/pdf/nihms361540.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To assess how threshold oppositional defiant disorder (ODD), inattention, and hyperactivity-impulsivity affect the response to atomoxetine versus methylphenidate. 

**METHOD: **
Systematic review of randomized controlled trials (RCTs; &gt;6 weeks follow-up). The primary measure was core symptom response-&gt;40% reduction in ADHD Rating Scale-IV-Parent Version: investigator administered and scored total or domain subscores, as appropriate. 

**RESULTS: **
Data from 1,391 children and adolescents (823 atomoxetine, 568 methylphenidate; 7 RCTs) were meta-analyzed. The mean difference in response rates for patients with ODD was 0.6% (95% confidence interval [CI] = -11.9%-13.1%). The &quot;without ODD&quot; patient group showed significant between-trial heterogeneity (p &lt; .001). Response rate differences for patients meeting the threshold for inattention or hyperactivity-impulsivity were -3.1% (95% CI = -11.5%-5.3%) and -4.9% (95% CI = -14.3%-4.4%), respectively. 

**CONCLUSIONS: **
Meeting the threshold criteria for oppositionality, inattention, or hyperactivity-impulsivity did not alter core ADHD symptom response to atomoxetine versus methylphenidate, which was equivalent.
AD  - van Wyk,Gregory W. Eli Lilly Australia Pty Ltd, West Ryde, NSW, Australia. van_wyk_gregory_wayne@lilly.com
AN  - 21289234
AU  - van
AU  - Wyk,
AU  - G.
AU  - W.
AU  - Hazell,
AU  - P.
AU  - L.
AU  - Kohn,
AU  - M.
AU  - R.
AU  - Granger,
AU  - R.
AU  - E.
AU  - Walton,
AU  - R.
AU  - J.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1087054710389989
DP  - Ovid Technologies
J2  - J Atten Disord
KW  - Adolescent *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] *Attention Deficit and Disruptive Behavior Disorders/dt [Drug Therapy] *Central Nervous System Stimulants/tu [Therapeutic Use] Child Humans *Hyperkinesis/dt [Drug Therapy] *Meth
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - van Wyk, Gregory W Hazell, Philip L Kohn, Michael R Granger, Renee E Walton, Richard J
PY  - 2012
SP  - 314-24
T2  - Journal of Attention Disorders
TI  - How oppositionality, inattention, and hyperactivity affect response to atomoxetine versus methylphenidate: a pooled meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21289234 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21289234&amp;id=doi:10.1177%2F1087054710389989&amp;issn=1087-0547&amp;isbn=&amp;volume=16&amp;issue=4&amp;spage=314&amp;pages=314-24&amp;date=2012&amp;title=Journal+of+Attention+Disorders&amp;atitle=How+oppositionality%2C+inattention%2C+and+hyperactivity+affect+response+to+atomoxetine+versus+methylphenidate%3A+a+pooled+meta-analysis.&amp;aulast=van+Wyk&amp;pid=%3Cauthor%3Evan+Wyk+GW%3C%2Fauthor%3E%3CAN%3E21289234%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://jad.sagepub.com/content/16/4/314http://jad.sagepub.com/content/16/4/314.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/1087054710389989?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 16
ER  -
TY  - JOUR
AB  - Children from substance-affected families show an elevated risk for developing own substance-related or other mental disorders. Therefore, they are an important target group for preventive efforts. So far, such programs for children of substance-involved parents have not been reviewed together. 

We conducted a comprehensive systematic review to identify and summarize evaluations of selective preventive interventions in childhood and adolescence targeted at this specific group.
 
From the overall search result of 375 articles, 339 were excluded, 36 full texts were reviewed. From these, nine eligible programs documented in 13 studies were identified comprising four school-based interventions (study 1-6), one community-based intervention (study 7-8), and four family-based interventions (study 9-13). Studies&#039; levels of evidence were rated in accordance with the Scottish Intercollegiate Guidelines Network (SIGN) methodology, and their quality was ranked according to a score adapted from the area of meta-analytic family therapy research and consisting of 15 study design quality criteria. Studies varied in program format, structure, content, and participants. They also varied in outcome measures, results, and study design quality. We found seven RCT&#039;s, two well designed controlled or quasi-experimental studies, three well-designed descriptive studies, and one qualitative study. 

There was preliminary evidence for the effectiveness of the programs, especially when their duration was longer than ten weeks and when they involved children&#039;s, parenting, and family skills training components. Outcomes proximal to the intervention, such as program-related knowledge, coping-skills, and family relations, showed better results than more distal outcomes such as self-worth and substance use initiation, the latter due to the comparably young age of participants and sparse longitudinal data. However, because of the small overall number of studies found, all conclusions must remain tentative. More evaluations are needed and their quality must be improved. New research should focus on the differential impact of program components and delivery mechanisms. It should also explore long-term effects on children substance use, delinquency, mental health, physical health and school performance. To broaden the field, new approaches to prevention should be tested in diverse cultural and contextual settings.
AD  - [Broening, Sonja; Kruse, Katja; Sack, Peter-Michael; Ruths, Sylvia; Thomasius, Rainer] Univ Med Ctr Hamburg Eppendorf, Ctr Psychosocial Med, German Ctr Addict Res Childhood &amp; Adolescence, D-20246 Hamburg, Germany. [Kumpfer, Karol] Univ Utah, Coll Hlth, Dept Hlth Promot &amp; Educ, Salt Lake City, UT 84112 USA. [Schaunig-Busch, Ines; Moesgen, Diana; Pflug, Ellen; Klein, Michael] Catholic Univ Appl Sci Nordrhein Westfalen, German Inst Addict &amp; Prevent Res, D-50688 Cologne, Germany. Broning, S (reprint author), Univ Med Ctr Hamburg Eppendorf, Ctr Psychosocial Med, German Ctr Addict Res Childhood &amp; Adolescence, Martinistr 52, D-20246 Hamburg, Germany. s.broening@uke.de
AN  - WOS:000310745600001
AU  - Broning,
AU  - S.
AU  - Kumpfer,
AU  - K.
AU  - Kruse,
AU  - K.
AU  - Sack,
AU  - P.
AU  - M.
AU  - Schaunig-Busch,
AU  - I.
AU  - Ruths,
AU  - S.
AU  - Moesgen,
AU  - D.
AU  - Pflug,
AU  - E.
AU  - Klein,
AU  - M.
AU  - Thomasius,
AU  - R.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/1747-597X-7-23
J2  - Subst/ Abus. Treatment Prev. Pol.
KW  - Children of alcoholics Children of substance abusers Prevention programs Familial substance use USE DISORDERS ALCOHOL-USE OUTCOME MEASURES PROBLEM DRINKERS RISK-FACTORS DRUG-ABUSE FOLLOW-UP INTERVENTIONS PARENTS METAANALYSIS Substance Abuse
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 032UW Times Cited: 3 Cited Reference Count: 87 Broening, Sonja Kumpfer, Karol Kruse, Katja Sack, Peter-Michael Schaunig-Busch, Ines Ruths, Sylvia Moesgen, Diana Pflug, Ellen Klein, Michael Thomasius, Rainer 4 BIOMED CENTRAL LTD LONDON SUBST ABUSE TREAT PR
PY  - 2012
SP  - 17
T2  - Substance Abuse Treatment Prevention and Policy
TI  - Selective prevention programs for children from substance-affected families: a comprehensive systematic review
UR  - &lt;Go to ISI&gt;://WOS:000310745600001http://www.substanceabusepolicy.com/content/pdf/1747-597X-7-23.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
Truancy is a significant problem in the U.S. and in other countries around the world. Truancy has been linked to serious immediate and far-reaching consequences for youth, families, and schools and communities, leading researchers, practitioners, and policy makers to try to understand and to address the problem. Although numerous and significant steps have been taken at the local, state, and national levels to reduce truancy, the rates of truancy have at best remained stable or at worst been on the rise, depending on the indicator utilized to assess truancy rates. The costs and impact of chronic truancy are significant, with both short- and long-term implications for the truant youth as well as for the family, school, and community. Although several narrative reviews and one meta-analysis of attendance and truancy interventions have attempted to summarize the extant research, there are a number of limitations to these reviews. It is imperative that we systematically synthesize and examine the evidence base to provide a comprehensive picture of interventions that are being utilized to intervene with chronic truants, to identify interventions that are effective and ineffective, and to identify gaps and areas in which more research needs to be conducted to better inform practice and policy. 

**OBJECTIVES** 
The main objective of this systematic review was to examine the effects of interventions on school attendance to inform policy, practice, and research. The questions guiding this study were: 1) Do truancy programs with a goal of increasing student attendance for truant youth affect school attendance behaviors of elementary and secondary students with chronic attendance problems? 2) Are there differences in the effects of school-based, clinic/community-based, and court-based programs? 3) Are some modalities (i.e., family, group, multimodal) more effective than others in increasing student attendance? 

**SEARCH STRATEGY** 
A systematic and comprehensive search process was employed to locate all possible studies between 1990 and 2009, with every effort made to include both published and unpublished studies to minimize publication bias. A wide range of electronic bibliographic databases and research registers was searched, websites of relevant research centers and groups were mined for possible reports, over 200 e-mails and letters were sent to programs listed in large databases of truancy programs compiled by the National Center for School Engagement and the National Dropout Prevention Center, and contact with researchers in the field of truancy and absenteeism was attempted. In addition, we examined reference lists of all previous reviews as well as citations in research reports for potential studies. 

**SELECTION CRITERIA** 
Studies eligible for this review were required to meet several eligibility criteria. Studies must have utilized a randomized, quasi-experimental, or single-group pre-posttest design with the aim of evaluating the effectiveness of interventions with a stated primary goal of increasing student attendance (or decreasing absenteeism) among chronic truant students. Studies must have measured an attendance outcome and reported sufficient data to calculate an effect size. Finally, studies must have been published between 1990 and 2009 in the United States, United Kingdom, Australia, or Canada. 

**DATA COLLECTION AND ANALYSIS** 
A total of 28 studies, reported in 26 reports, met final eligibility criteria and were included in this review and meta-analysis. Of the studies that were included, 5 utilized a randomized design (RCT), 11 utilized a quasi-experimental design (QED), and 12 utilized a single group pre-posttest design (SGPP). All eligible studies were coded using a structured coding instrument, with 20% of studies coded by a second coder. Descriptive analysis was conducted to examine and describe data related to the characteristics of the included studies. Analysis of the mean effect size, the heterogeneity of effect sizes, and the relationship between effect size and methodological and substantive c aracteri tics of the interventions was also conducted separately for the RCT/QED studies and the SGPP studies. The effect sizes were calculated using the standardized mean difference effect size statistic, correcting for small sample size using Hedges&rsquo; g (Hedges, 1992). Assuming a mixed effects model, the analog to the ANOVA and bivariate meta-regression frameworks were used to examine potential moderating variables related to study, participant, and intervention characteristics. 

**RESULTS** 
The meta-analytic findings demonstrated a significant overall positive and moderate mean effect of interventions on attendance outcomes. The mean effect size for interventions examined in the included RCT studies was .57 and the mean effect size for the QED studies was .43. No significant differences were observed between the RCT and QED studies in the magnitude of the treatment effect (Qb= .28, p &gt;.05). The mean effect size of interventions examined using an SGPP design was .95. A moderate effect on attendance outcomes is encouraging; however, the overall mean effect size is masked by a large amount of heterogeneity, indicating significant variance in effect sizes between studies. Moderator analyses found no significant differences in mean effects between studies on any moderating variable tested. No differences were found between school-, court-, or community-based programs or between different modalities of programs. The duration of the intervention also did not demonstrate any association with effect size. Collaborative programs and multimodal interventions produced statistically similar effects on attendance as non-collaborative and single-modality programs, which runs counter to the prevailing beliefs and recommendations for best practices in truancy reduction found in the literature. Other significant findings from this study relate to methodological shortcomings, the absence of important variables as well as gaps in the evidence base. These findings include the lack of inclusion of minority students and a lack of reporting and statistical analysis of demographic variables, particularly race/ethnicity and socioeconomic status (SES). Given that race and SES have been linked to absenteeism, the absence of this data was surprising. The majority of studies also lacked adequate descriptions of the interventions, making replication of the intervention difficult, and failed to measure and report long-term outcomes. 

**AUTHORS&rsquo; CONCLUSIONS** 
Overall, the findings from this study suggest that chronic truant students benefit from interventions targeting attendance behaviors; thus it is important and worthwhile to intervene with chronic truant youth. Given the minimal differences in effects across program types and modalities, no one program type or modality stands out as being more effective than any other. Although no statistically significant differences in effects were found between types and modalities of interventions included in this review, there was a lack of available evidence to support the general belief (and popular &ldquo;best-practice&rdquo; recommendations) that collaborative and multimodal interventions are more effective than programs that are not collaborative and single modal interventions. Due to the small sample size and large heterogeneity between studies and within groups of studies, caution must be used when interpreting and applying the findings from this meta-analysis. Overall, the studies included in the review improved attendance by an average of 4.69 days, almost a full school week. However, although the interventions included in this study were, overall, found to be effective, the mean rates of absenteeism at posttest in most studies remained above acceptable levels. This finding indicates the need for additional work and research. Developing more effective interventions and policies as well as studying outcomes of interventions, particularly with vulnerable and at-risk populations, is crucial to combating absenteeism. The gaps and deficiencies identified in this study also affirm the need for increasing and streng hening the ev dence base on which current policies and practices rest. Although additional outcome research is necessary, more of the same is not sufficient. Significant improvements in the quality of truancy intervention research are required and identified gaps need to be addressed. Recommendations to improve the quality and fill gaps in truancy intervention research are discussed here. In addition, given the significant and pervasive deficiencies in the extant research, a critical analysis of the practices, assumptions, and sociopolitical contexts underlying truancy intervention research seems warranted.
AU  - Maynard,
AU  - B.
AU  - R.
AU  - McCrea,
AU  - K.
AU  - T.
AU  - Kelly,
AU  - M.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2012.10
KW  - School attendance
KW  - Schoolchildren
KW  - Truancy
PY  - 2012
T2  - Campbell Systematic Reviews
TI  - Indicated Truancy Interventions: Effects on School Attendance Among Chronic Truant Students
ER  -
TY  - JOUR
AB  - **Topic: **
Habit reversal training (HRT) is emerging as an efficacious behavioral intervention for Tourette syndrome in children and adults. 

**Purpose: **
The purpose of this article is to review the recent literature investigating the efficacy of HRT for treating children with chronic tic disorders. 

**Sources: **
This review examines single-subject design studies and randomized, controlled trials of HRT conducted in children with chronic tic disorders since 2000. 

**Conclusions: **
Intervention built on HRT appears to be effective for decreasing tic severity in children and adolescents. Results from a recent multisite trial suggest that incorporation of functional analysis may enhance the effectiveness of traditional HRT. 

&copy; 2012 Wiley Periodicals, Inc.
AD  - (Hwang) Connecticut Children&#039;s Medical Center, Inpatient Management Team, Hospital Medicine, Hartford, CT, United States (Tillberg) Child Study Center, New Haven, CT, United States (Scahill) Nursing and Child Psychiatry, Yale University School of Nursing and Child Study Center, New Haven, CT, United States L. Scahill, Nursing and Child Psychiatry, Yale University School of Nursing and Child Study Center, New Haven, CT, United States. E-mail: Lawrence.Scahill@yale.edu
AN  - 23121140
AU  - Hwang,
AU  - G.
AU  - C.
AU  - Tillberg,
AU  - C.
AU  - S.
AU  - Scahill,
AU  - L.
DA  - November
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/jcap.12002
DP  - Ovid Technologies
KW  - Behavior therapy Comprehensive behavioral intervention for tics Functional analysis Habit reversal therapy Pediatrics Tic disorder Tourette syndrome adolescent adult article child cognitive therapy Gilles de la Tourette syndrome/rh [Rehabilitation] habi
L1  - internal-pdf://1364454330/Hwang-2012-Habit Reversal Training for Childre.pdf
LA  - English
PY  - 2012
SP  - 178-183
T2  - Journal of Child and Adolescent Psychiatric Nursing
TI  - Habit Reversal Training for Children With Tourette Syndrome: Update and Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed11&amp;AN=23121140 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:23121140&amp;id=doi:10.1111%2Fjcap.12002&amp;issn=1073-6077&amp;isbn=&amp;volume=25&amp;issue=4&amp;spage=178&amp;pages=178-183&amp;date=2012&amp;title=Journal+of+Child+and+Adolescent+Psychiatric+Nursing&amp;atitle=Habit+Reversal+Training+for+Children+With+Tourette+Syndrome%3A+Update+and+Review&amp;aulast=Hwang&amp;pid=%3Cauthor%3EHwang+G.C.%3C%2Fauthor%3E%3CAN%3E23121140%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/jcap.12002/asset/jcap12002.pdf?v=1&amp;t=ib8zt6g3&amp;s=0ef2978325982de7446c5f47a6124d368769017b
UR  - http://onlinelibrary.wiley.com/store/10.1111/jcap.12002/asset/jcap12002.pdf?v=1&amp;t=j8ygfj5x&amp;s=13d5711a04eee7b5000b6b02eac553d9c478853b
VL  - 25
ER  -
TY  - JOUR
AB  - Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder. For a child to be diagnosed with ADHD, adults such as parents, carers, healthcare workers or teachers must have noticed higher levels of inattention, hyperactivity and impulsivity in the child before the age of seven years compared to children of similar age. The inattention, hyperactivity and impulsivity must be observed in a range of situations, for a substantial period of time and cause impairment to the child&rsquo;s learning or social development. Parent training programmes aim to equip parents with techniques to manage their child&#039;s &#039;difficult&#039; or ADHD-related behaviour (that is their inattention and hyperactivity-impulsivity). We found five randomised controlled studies that met our inclusion criteria. Four set out to improve children&#039;s general behaviour and one focused specifically on how parents could help their children make friends. All studies were small and their quality varied. Results from these studies were somewhat encouraging as far as parental stress and general child behaviour were concerned, but were uncertain with regard to other important outcomes including ADHD-related behaviour. No study provided data on the key outcomes of achievement in school, harmful effects or parent knowledge of ADHD. There was no evidence to say whether parent training is better delivered in groups or individually. The evidence we found was limited in terms of the size of the trials and in their quality, and therefore we do not think it can be used as the basis for guidelines of treatment of ADHD in clinics or schools. We believe more research is needed and that it should ensure better reporting of the study procedures and results.
AU  - Zwi,
AU  - M.
AU  - Jones,
AU  - H.
AU  - Thorgaard,
AU  - C.
AU  - York,
AU  - A.
AU  - Shatford,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003018.pub3
KW  - Child behaviour
KW  - Attention deficit disorder
KW  - Children (age group)
KW  - Parent education
PY  - 2012
T2  - Campbell Systematic Reviews
TI  - Parent training interventions for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 5 to 18 years
ER  -
TY  - JOUR
AB  - Objective: Mental illness in parents affects the mental health of their children. A systematic review and a meta-analysis of the effectiveness of interventions to prevent mental disorders or psychological symptoms in the offspring were performed. Method: The Cochrane, MEDLINE, EMBASE, and PsycINFO databases were searched for randomized controlled trials of interventions in parents with mental disorders. Outcomes in the child included incident mental disorders of the same nature and internalizing (negative emotions, depressive symptoms, anxiety) or externalizing (hyperactivity, aggressiveness, behavioral problems) symptoms. Relative risks and standardized mean differences in symptom scores were combined in random-effects meta-analysis. Results: Thirteen trials including 1,490 children were analyzed. Interventions included cognitive, behavioral, or psychoeducational components. Seven trials assessed the incidence of mental disorders and seven trials assessed symptoms. In total 161 new diagnoses of mental illness were recorded, with interventions decreasing the risk by 40% (combined relative risk 0.60, 95% Cl 0.45-0.79). Symptom scores were lower in the intervention groups: standardized mean differences were -0.22 (95% CI -0.37 to -0.08) for internalizing symptoms (p = .003) and -0.16 (95% confidence interval -0.36 to 0.04) for externalizing symptoms (p = .12). Conclusions: Interventions to prevent mental disorders and psychological symptoms in the offspring of parents with mental disorders appear to be effective. J. Am. Acad. Child Adolesc. Psychiatry, 2012;51(1):8-17.
AD  - [Siegenthaler, Eliane] Univ Bern, Univ Psychiat Hosp, Univ Child Serv, CH-3010 Bern, Switzerland. [Munder, Thomas; Egger, Matthias] Univ Bern, Inst Social &amp; Prevent Med, CH-3010 Bern, Switzerland. [Egger, Matthias] Univ Bristol, Bristol BS8 1TH, Avon, England. Siegenthaler, E (reprint author), Univ Bern, Univ Psychiat Hosp, Univ Child Serv, CH-3010 Bern, Switzerland. eliane.siegenthaler@gef.be.ch
AN  - WOS:000298530300003
AU  - Siegenthaler,
AU  - E.
AU  - Munder,
AU  - T.
AU  - Egger,
AU  - M.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jaac.2011.10.018
J2  - J. Am. Acad. Child Adolesc. Psychiatr.
KW  - preventive intervention mentally ill parents internalizing and externalizing symptoms randomized controlled trials meta-analysis RANDOMIZED CONTROLLED-TRIAL SUBSTANCE USE DISORDERS DEPRESSED PARENTS CHILD PSYCHOPATHOLOGY POSTNATAL DEPRESSION MATERNAL DE
L1  - internal-pdf://3443975624/Siegenthaler-2012-Effect of Preventive Interve.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 868NP Times Cited: 20 Cited Reference Count: 47 Siegenthaler, Eliane Munder, Thomas Egger, Matthias 20 ELSEVIER SCIENCE BV AMSTERDAM J AM ACAD CHILD PSY
PY  - 2012
SP  - 8-17
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Effect of Preventive Interventions in Mentally Ill Parents on the Mental Health of the Offspring: Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000298530300003http://ac.els-cdn.com/S0890856711009932/1-s2.0-S0890856711009932-main.pdf?_tid=48cff0b2-1674-11e5-b805-00000aab0f6b&amp;acdnat=1434712619_563d1b52bf3daa1438ae2ee9566d8794
VL  - 51
ER  -
TY  - JOUR
AB  - It has been suggested that a deficiency in folic acid during early, critical central nervous system development may result in persistent cognitive and behavioral effects.

The purpose of this systematic review was to evaluate evidence regarding whether folic acid supplementation during pregnancy and early life influences mental performance outcomes in children. 

The following electronic databases were searched through December 2009 for studies relevant to mental performance and folic acid: MEDLINE, EMBASE and The Cochrane Library; additional references were obtained from reviewed articles. Only randomized controlled trials (RCTs) were included. Of 8 RCTs identified, only 2 met the inclusion criteria. 

Both studies involved periconceptional, multivitamin-containing, folic acid supplementation. Evidence from these 2 RCTs suggests that such supplementation does not affect the postnatal mental development of infants at a mean age of 11 mo, the developmental quotient (DQ) at 2 y of age, or the intelligence quotient (IQ) and Goodenough man drawing test quotient (DrQ) at 6 y of age. 

We conclude that the use of multivitamin-containing folic acid supplementation during pregnancy is associated with no benefit to the mental performance of children. These findings should be interpreted with caution due to the very limited number of studies included in this systemic review.
AN  - 22823344
AU  - Skorka,
AU  - A.
AU  - Gieruszczak-Bialek,
AU  - D.
AU  - Piescik,
AU  - M.
AU  - Szajewska,
AU  - H.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1080/10408398.2010.515042
L1  - internal-pdf://2469011650/Skorka-2012-Effects of prenatal and_or postnat.pdf
PY  - 2012
SP  - 959-64
T2  - Critical Reviews in Food Science &amp; Nutrition
TI  - Effects of prenatal and/or postnatal (maternal and/or child) folic acid supplementation on the mental performance of children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=22823344
UR  - https://www.tandfonline.com/doi/pdf/10.1080/10408398.2010.515042?needAccess=true
VL  - 52
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
Since autism was first described, major difficulties in social interaction have been a defining feature of individuals with autism spectrum disorders (ASD). Social skills groups are a common intervention for individuals with ASD. Although a frequently recommended practice, the few studies that have addressed the efficacy of social skills groups have shown mixed results. OBJECTIVES To determine the effectiveness of social skills groups for improving social competence, social communication, and quality of life for people with ASD who are six to 21 years of age. 

**SEARCH STRATEGY** 
We searched the following databases in December 2011: CENTRAL (2011 Issue 4), MEDLINE (1948 to November Week 3, 2011), EMBASE (1980 to Week 50, 2011), PsycINFO (1887 to December Week 2, 2011), CINAHL (1937 to current), ERIC (1966 to current), Sociological Abstracts (1952 to current), OCLC WorldCat (12 December 2011), Social Science Citation Index (1970 to 16 December 2011), and the metaRegister of Controlled Trials (20 December 2011). We also searched the reference lists of published papers. 

**SELECTION CRITERIA** 
Randomized control trials (RCTs) comparing treatment (social skills groups) with a control group who were not receiving the treatment for participants aged six to 21 years with ASD. The control group could be no intervention, wait list, or treatment as usual. Outcomes sought were standardized measures of social competence, social communication, quality of life, emotion recognition, and any other specific behaviors. 

**DATA COLLECTION AND ANALYSIS** 
Two review authors independently selected and appraised studies for inclusion and assessed the risk of bias in each included study. All outcome data were continuous and standardized mean difference effect sizes (ES) with small sample correction were calculated. We conducted random-effects meta-analysis where possible. 

**RESULTS** 
We included five RCTs evaluating the effects of social skills groups in 196 participants with ASD aged 6 to 21 years old. The results show there is some evidence that social skills groups improve overall social competence (ES = 0.47, 95% confidence interval (CI) 0.16 to 0.78, P = 0.003) and friendship quality (ES = 0.41, 95% CI 0.02 to 0.81, P = 0.04) for this population. No differences were found between treatment and control groups in relation to emotional recognition (ES = 0.34, 95% CI -0.20 to 0.88, P = 0.21) assessed in two studies or social communication as related to the understanding of idioms (ES = 0.05, 95% CI -0.63 to 0.72, P = 0.89), which was assessed in only one study. Two additional quality of life outcomes were evaluated, with results of single studies suggesting decreases in loneliness (ES = -0.66, 95% CI -1.15 to -0.17) but no effect on child or parental depression. No adverse events were reported. Given the nature of the intervention and the selected outcome measures, the risk of performance and detection bias are high. There is limited generalizability from the studies as they were all conducted in the US; they focused mainly on children aged 7 to 12, and the participants were all of average or above average intelligence. 

**AUTHORS&rsquo; CONCLUSIONS** 
There is some evidence that social skills groups can improve social competence for some children and adolescents with ASD. More research is needed to draw more robust conclusions, especially with respect to improvements in quality of life.
AU  - Reichow,
AU  - B.
AU  - Steiner,
AU  - A.
AU  - Volkmar,
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2012.16
KW  - Social behaviour
KW  - Communication skills
KW  - Autism
PY  - 2012
T2  - Campbell Systematic Reviews
TI  - Social skills group for people aged 6 to 21 with autism spectrum disorders (ASD)
ER  -
TY  - JOUR
AB  - **Background:** 
Information on the impact of available interventions that address adolescent substance use and delinquency can inform investment choices. This article aims to identify and evaluate early interventions that target adolescent substance use as a primary outcome, and criminal or delinquent behaviours as a secondary outcome. 

**Method:** 
A systematic review of early interventions for adolescent substance use and behavioural outcomes was conducted. 

**Results:** 
We identified nine studies using specific search strategies. All but one of the studies reported the use of brief intervention strategies. Only seven studies contained information which allowed for the calculation of an effect size, and were therefore included in the meta-analysis. The overall effect size for all outcomes combined was small but significant (g = 0.25, p &lt; 0.001). The overall outcome for substance use was also small but significant (g = 0.24, p &lt; 0.001). For studies with behavioural outcomes, the overall effect size reached significance (g = 0.28, p &lt; 0.001). In general, subgroup analysis showed that individual interventions with more than one session had a stronger effect on the outcomes of interest. 

**Conclusions:** 
Early interventions for adolescent substance use do hold benefits for reducing substance use and associated behavioural outcomes. Interventions are most promising if delivered in an individual format and over multiple sessions. One intervention in particular had large effect sizes. As all the interventions were tested in developed countries, further testing is needed in low- and middle-income countries where there is a lack of research on evidence-based interventions for adolescent risk behaviours. Additional recommendations for policy and practice are provided in this paper.
AD  - [Carney, Tara; Myers, Bronwyn] MRC, Alcohol &amp; Drug Abuse Res Unit, Cape Town, South Africa. [Myers, Bronwyn] Univ Cape Town, Dept Psychiat &amp; Mental Hlth, ZA-7925 Cape Town, South Africa. Carney, T (reprint author), MRC, Alcohol &amp; Drug Abuse Res Unit, Cape Town, South Africa. tara.carney@mrc.ac.za
AN  - WOS:000313164900001
AU  - Carney,
AU  - T.
AU  - Myers,
AU  - B.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/1747-597X-7-25
J2  - Subst/ Abus. Treatment Prev. Pol.
KW  - Systematic review Early intervention Substance use Behavioural outcomes Adolescence HIGH-SCHOOL-STUDENTS BRIEF MOTIVATIONAL INTERVENTION RANDOMIZED CONTROLLED-TRIAL RISK ALCOHOL BEHAVIOR DRUG ASSOCIATION VIOLENCE YOUTH Substance Abuse
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 065QY Times Cited: 5 Cited Reference Count: 37 Carney, Tara Myers, Bronwyn 5 BIOMED CENTRAL LTD LONDON SUBST ABUSE TREAT PR
PY  - 2012
SP  - 15
T2  - Substance Abuse Treatment Prevention and Policy
TI  - Effectiveness of early interventions for substance-using adolescents: findings from a systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000313164900001http://www.substanceabusepolicy.com/content/pdf/1747-597X-7-25.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - Background: Interventions to promote positive parenting are often reported to offer good outcomes for children but they can consume substantial resources and they require rigorous appraisal. Methods: Evaluations of the Triple P parenting program were subjected to systematic review and meta-analysis with analysis of biases. PsychInfo, Embase and Ovid Medline were used as data sources. We selected published articles reporting any child-based outcome in which any variant of Triple P was evaluated in relation to a comparison condition. Unpublished data, papers in languages other than English and some book chapters were not examined. Studies reporting Eyberg Child Behavior Inventory or Child Behavior Checklist scores as outcomes were used in the meta-analysis. Results: A total of 33 eligible studies was identified, most involving media-recruited families. Thirty-one of these 33 studies compared Triple P interventions with waiting list or no-treatment comparison groups. Most papers only reported maternal assessments of child behavior. Twenty-three papers were incorporated in the meta-analysis. No studies involved children younger than two-years old and comparisons of intervention and control groups beyond the duration of the intervention were only possible in five studies. For maternally-reported outcomes the summary effect size was 0.61 (95% CI 0.42, 0.79). Paternally-reported outcomes following Triple P intervention were smaller and did not differ significantly from the control condition (effect size 0.42 (95% CI -0.02, 0.87)). The two studies involving an active control group showed no between-group differences. There was limited evidence of publication bias, but there was substantial selective reporting bias, and preferential reporting of positive results in article abstracts. Thirty-two of the 33 eligible studies were authored by Triple-P affiliated personnel. No trials were registered and only two papers contained conflict of interest statements. Conclusions: In volunteer populations over the short term, mothers generally report that Triple P group interventions are better than no intervention, but there is concern about these results given the high risk of bias, poor reporting and potential conflicts of interest. We found no convincing evidence that Triple P interventions work across the whole population or that any benefits are long-term. Given the substantial cost implications, commissioners should apply to parenting programs the standards used in assessing pharmaceutical interventions. See related commentary: http://www.biomedcentral.com/1741-7015/10/145
AD  - [Wilson, Philip] Univ Aberdeen, Ctr Hlth Sci, Ctr Rural Hlth, Inverness IV2 3JH, Scotland. [Rush, Robert] Queen Margaret Univ, Dept Hlth Sci, Musselburgh EH21 6UU, Scotland. [Puckering, Christine; Sim, Fiona; Allely, Clare S.; Doku, Paul; Gillberg, Christopher] Univ Glasgow, Royal Hosp Sick Children, Inst Hlth &amp; Wellbeing, Glasgow G3 8SJ, Lanark, Scotland. [McConnachie, Alex] Univ Glasgow, Robertson Ctr Biostat, Glasgow G12 8QQ, Lanark, Scotland. Wilson, P (reprint author), Univ Aberdeen, Ctr Hlth Sci, Ctr Rural Hlth, Old Perth Rd, Inverness IV2 3JH, Scotland. p.wilson@abdn.ac.uk
AN  - WOS:000313052000001
AU  - Wilson,
AU  - P.
AU  - Rush,
AU  - R.
AU  - Hussey,
AU  - S.
AU  - Puckering,
AU  - C.
AU  - Sim,
AU  - F.
AU  - Allely,
AU  - C.
AU  - S.
AU  - Doku,
AU  - P.
AU  - McConnachie,
AU  - A.
AU  - Gillberg,
AU  - C.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1186/1741-7015-10-130
J2  - BMC Med.
KW  - parenting public health child psychology behavioral family intervention systematic review meta-analysis BEHAVIORAL FAMILY INTERVENTION RANDOMIZED CONTROLLED-TRIAL CONDUCT PROBLEMS CHILD-BEHAVIOR DEVELOPMENTAL-DISABILITIES CLINICAL-TRIAL REMOTE AREAS PRI
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 064DT Times Cited: 16 Cited Reference Count: 65 Wilson, Philip Rush, Robert Hussey, Susan Puckering, Christine Sim, Fiona Allely, Clare S. Doku, Paul McConnachie, Alex Gillberg, Christopher NIHR PW is academic advisor to the evaluation of the Glasgow Parenting Support Framework, which has Triple P as one of its core components. AMcC provides statistical advice to this evaluation. Along with AMcC and CP, PW is a co-investigator in a NIHR funded trial comparing an antenatal Triple P intervention with another parenting program, Mellow Parenting. CP is an author of the Mellow Parenting program, which is owned by a charity, and she is employed as a trainer for this program. Other authors report no conflicts of interest. 16 BIOMED CENTRAL LTD LONDON BMC MED
PY  - 2012
SP  - 16
T2  - Bmc Medicine
TI  - How evidence-based is an &#039;evidence-based parenting program&#039;? A PRISMA systematic review and meta-analysis of Triple P
UR  - &lt;Go to ISI&gt;://WOS:000313052000001http://www.biomedcentral.com/content/pdf/1741-7015-10-130.pdf
VL  - 10
ER  -
TY  - JOUR
AB  - **Background:** 
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders, ranging in severity and characterised by early onset of delay and deviance in the development of social interaction, and verbal and nonverbal communication. ASD is associated with restricted and/or stereotyped interests or behaviours. Tricyclic antidepressants (TCAs) block noradrenaline and serotonin reuptake, increasing the availability of these neurotransmitters in the central nervous system. Via their impact on serotonin, TCAs have been used in the treatment of autistic symptoms and comorbidities in individuals with ASD.&nbsp;&nbsp;

**Objectives:** 
To determine if treatment with tricyclic antidepressants:1) improves the core features of autism, including restricted social interaction, restricted communication, and stereotypical and repetitive behaviours; 2) improves non-core features such as challenging behaviours; 3) improves comorbid states, such as depression and anxiety; 4) causes adverse effects.Search methods: We ran the latest searches for this review on 23 May 2011. We searched: Cochrane Central Register of Controlled Trials (CENTRAL), 2011 Issue 2, MEDLINE (1948 to May Week 2, 2011), EMBASE (1980 to 2011 Week 2), PsycINFO (1887 to current), CINAHL (1937 to current). We also searched Dissertation Abstracts International via Dissertation Express, and the metaRegister of Controlled Trials.

**Selection criteria:** 
Randomised controlled trials of any dose, duration and frequency of oral TCAs compared with placebo, in children and adolescents with a diagnosis of ASD, where at least one standardised outcome measure had been used.

**Data collection and analysis:** 
Two review authors independently selected and appraised the studies for inclusion and risk of bias. All data were continuous.

**Main results:** 
Three studies met the inclusion criteria for this review. Two studies used clomipramine and one used tianeptine. All three trials were small, with between 12 and 32 participants. One of the clomipramine trials involved children and young adults, while the other two trials enrolled only children. Due to heterogeneity in study participant characteristics, the TCA medications investigated and the outcome measures used, we were not able to perform any meta-analysis.In only one of the three studies was there any indication that giving children tianeptine could be effective in the short term. In this study, parents and teachers reported that it reduced irritability, hyperactivity, inadequate eye contact and inappropriate speech, but clinician ratings found no significant impact on these symptoms. There were also significant adverse effects, including increased drowsiness and reduced activity levels in these individuals while being treated with tianeptine. The evidence of the impact of clomipramine in the two studies is contradictory. There was evidence of improvement in autistic symptoms, irritability and obsessive-compulsive disorder type symptoms, but conflicting evidence in relation to hyperactivity across the two studies, and no significant changes found with inappropriate speech. There were also adverse effects reported with the use of clomipramine. Although side effect ratings were not significantly different to placebo, there were significant dropout rates in the clomipramine arm of one study.

**Authors&#039; conclusions:**
Clinicians considering the use of TCAs need to be aware of the limited and conflicting evidence of effect and the side effect profile when discussing this treatment option with people who have ASD and their carers. Further research is required before TCAs can be recommended for treatment of individuals with ASD.
AN  - CD008372
AU  - Hurwitz,
AU  - R.
AU  - Blackmore,
AU  - R.
AU  - Hazell,
AU  - P.
AU  - Williams,
AU  - K.
AU  - Woolfenden,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd008372.pub2
KW  - Antidepressive Agents, Tricyclic [adverse effects] [therapeutic use]
KW  - Child Development Disorders, Pervasive [drug therapy]
KW  - Clomipramine [adverse effects] [therapeutic use]
KW  - Thiazepines [adverse effects] [therapeutic use]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Young Adult[checkword]
KW  - Behav
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Tricyclic antidepressants for autism spectrum disorders (ASD) in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008372.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD008372.pub2/asset/CD008372.pdf?v=1&amp;t=iw7lc2cu&amp;s=bc8c5a2b597583b411a7d15481cff1a3066557c8
ER  -
TY  - JOUR
AB  - **BACKGROUND AND OBJECTIVE: **
Hyperactivity, impulsivity, and inattention (referred to as &quot;ADHD [attention-deficit/hyperactivity disorder] symptoms&quot;) occur in 41% to 78% of children with autism spectrum disorders (ASDs). These symptoms often affect quality of life, interfering with learning or interventions that target primary ASD symptoms. This practice pathway describes the guidelines for evaluation and treatment of children and adolescents with ASD and comorbid ADHD symptoms. 

**METHODS: **
Current research in this area is limited, and, therefore, these recommendations are based on a systematic literature review and expert consensus in the Autism Speaks Autism Treatment Network Psychopharmacology Committee. 

**RESULTS: **
The recommended practice pathway includes the Symptom Evaluation Pathway for systematic assessment of ADHD symptoms across settings; examination for comorbid sleep, medical, or psychiatric comorbidities that may contribute to symptoms; and evaluation of behavioral interventions that may ameliorate these symptoms. For children for whom medication is being considered to target the ADHD symptoms, the medication choice pathway provides guidance on the selection of the appropriate agent based on a review of available research, assessment of specific advantages and disadvantages of each agent, and dosing considerations. 

**CONCLUSIONS: **
These recommendations provide a framework for primary care providers treating children who have ASD and ADHD symptoms. Our systematic review of the current evidence indicates the need for more randomized controlled trials of the medications for ADHD symptoms in ASD. There will also be a need for studies of the effectiveness of these practice pathways in the future. 

Copyright &copy; 2012 by the American Academy of Pediatrics.
AD  - (Mahajan) Department of Psychiatry, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, Baltimore, MD, United States (Bernal) Department of Psychiatry, Kaiser Permanente Northern California, San Jose, CA, United States (Panzer) Department of Pediatrics, MassGeneral Hospital for Children, Boston, MA, United States (Whitaker) Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York, NY, United States (Roberts) Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada (Handen) Department of Psychiatry, University of Pittsburgh School of Medicine and Medical Center, Pittsburgh, PA, United States (Hardan) Department of Psychiatry and Behavioral Sciences, Stanford University Medical School, Stanford, CA, United States (Anagnostou) Department of Pediatrics, Holland Bloorview Kids Rehabilitation Hospital, University of Toronto, Toronto, ON, Canada (Veenstra-Vander Weele) Departments of Psychiatry, Pediatrics and Pharmacology, Vanderbilt University Medical Center, Nashville, TN, United States R. Mahajan, Kennedy Krieger Institute, Center for Autism and Related Disorders, 3901 Green Spring Ave, Baltimore, MD 21211, United States. E-mail: mahajan@kennedykrieger.org
AU  - Mahajan,
AU  - R.
AU  - Bernal,
AU  - M.
AU  - P.
AU  - Panzer,
AU  - R.
AU  - Whitaker,
AU  - A.
AU  - Roberts,
AU  - W.
AU  - Handen,
AU  - B.
AU  - Hardan,
AU  - A.
AU  - Anagnostou,
AU  - E.
AU  - Veenstra-Vander
AU  - Weele,
AU  - J.
DA  - November
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2012-0900J
DP  - Ovid Technologies
KW  - ADHD symptoms Autism spectrum disorders Hyperactivity Impulsivity Inattention article attention deficit disorder/dt [Drug Therapy] autism/dt [Drug Therapy] Autism Treatment Network child child behavior clinical practice cognitive defect/si [Side Effect]
L1  - internal-pdf://1850265964/Mahajan-2012-Clinical practice pathways for ev.pdf
LA  - English
PY  - 2012
SP  - S125-S138
T2  - Pediatrics
TI  - Clinical practice pathways for evaluation and medication choice for attention-deficit/hyperactivity disorder symptoms in autism spectrum disorders
UR  - http://pediatrics.aappublications.org/content/130/Supplement_2/S125.full.pdf+html http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed10&amp;AN=2012656893 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1542%2Fpeds.2012-0900J&amp;issn=0031-4005&amp;isbn=&amp;volume=130&amp;issue=SUPPL.+2&amp;spage=S125&amp;pages=S125-S138&amp;date=2012&amp;title=Pediatrics&amp;atitle=Clinical+practice+pathways+for+evaluation+and+medication+choice+for+attention-deficit%2Fhyperactivity+disorder+symptoms+in+autism+spectrum+disorders&amp;aulast=Mahajan&amp;pid=%3Cauthor%3EMahajan+R.%3C%2Fauthor%3E%3CAN%3E2012656893%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3Ehttp://pediatrics.aappublications.org/content/130/Supplement_2/S125.full.pdf
UR  - http://pediatrics.aappublications.org/content/pediatrics/130/Supplement_2/S125.full.pdf
VL  - 130
ER  -
TY  - JOUR
AB  - Attention-deficit/hyperactivity disorder is one of the most common neurobehavioral disorders defined by developmentally inappropriate levels of inattention, hyperactivity, and impulsivity. 
Symptoms begin in childhood and may persist into adolescence and adulthood. 

Currently available pharmacological treatment options for attention-deficit/hyperactivity disorder in children and adolescents include stimulants that are efficacious and well tolerated; however, many of these preparations require multiple daily dosing and have the potential for abuse. 

Lisdexamfetamine dimesylate, the first prodrug stimulant, was developed to provide a longer duration of effect. It demonstrates a predictable delivery of the active drug, d-amphetamine, with low interpatient variability, and has a reduced potential for abuse.

A literature search of the MEDLINE database and clinical trials register from 1995-2011, as well as relevant abstracts presented at annual professional meetings, on lisdexamfetamine dimesylate in children and adolescents were included for review. 

This article presents the pharmacokinetic profile, efficacy, and safety of lisdexamfetamine dimesylate for the treatment of attention-deficit/hyperactivity disorder in children and, more recently, in adolescents.
AD  - Najib,Jadwiga. Division of Pharmacy Practice, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York, NY, USA ; Department of Pharmacy, New York, NY, USA ; Department of Psychiatry, St Luke&#039;s-Roosevelt Hospital Center, New York, NY, USA.
AN  - 24600287
AU  - Najib,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2147/ahmt.s19815
DP  - Ovid Technologies
J2  - Adolesc
LA  - English
M3  - Review
N1  - Najib, Jadwiga
PY  - 2012
SP  - 51-66
T2  - Adolescent Health Medicine &amp; Therapeutics
TI  - Lisdexamfetamine in the treatment of adolescents and children with attention-deficit/hyperactivity disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=24600287
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24600287&amp;id=doi:10.2147%2FAHMT.S19815&amp;issn=1179-318X&amp;isbn=&amp;volume=3&amp;issue=&amp;spage=51&amp;pages=51-66&amp;date=2012&amp;title=Adolescent+Health+Medicine+%26+Therapeutics&amp;atitle=Lisdexamfetamine+in+the+treatment+of+adolescents+and+children+with+attention-deficit%2Fhyperactivity+disorder.&amp;aulast=Najib&amp;pid=%3Cauthor%3ENajib+J%3C%2Fauthor%3E%3CAN%3E24600287%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.dovepress.com/getfile.php?fileID=12699
VL  - 3
ER  -
TY  - JOUR
AB  - In adults, second-generation antipsychotics (SGAs) have a low frequency of extrapyramidal syndrome (EPS) and a moderate frequency of metabolic adverse effects. Here we aimed to assess short-term adverse effects of SGAs in children and adolescents. 

We searched for relevant studies in MEDLINE and EMBASE (1996-2010), Food and Drug Administration and European Medicines Agency clinical trial registries, and reference lists of review articles. We found 41 were short-term (3-12 weeks) controlled studies that evaluated SGA adverse effects in youths. 

Using Bayesian meta-analysis, we analyzed odds ratios (ORs) or mean average effects. Numbers of arms (subjects) in the 41 trials were aripiprazole, 10 (n = 671); olanzapine, 14 (n = 413); quetiapine, 10 (n = 446); risperidone, 25 (n = 1040); ziprasidone, 4 (n = 228); clozapine, 5 (n = 79); and placebo/untreated, 23 (n = 1138), totaling 93 arms (4015 patients). Clozapine was assessed only for weight gain and somnolence. 
Compared with placebo, significant treatment-related increases were observed for weight gain with olanzapine (mean +/- SD = 3.99 +/- 0.42 kg; 95% credible interval, 3.17-4.84 kg), clozapine (2.38 +/- 1.13 kg; 95% credible interval, 0.19-4.62 kg), risperidone (2.02 +/- 0.32 kg; 95% credible interval, 1.39-2.66 kg), quetiapine (1.74 +/- 0.38 kg; 95% credible interval, 0.99-2.5 kg), and aripiprazole (0.89 +/- 0.32 kg; 95% credible interval, 0.26-1.51 kg); glucose levels with risperidone (3.7 +/- 1.36 mg/dL; 95% credible interval, 1.08-6.42 mg/dL) and olanzapine (2.09 +/- 1.08 mg/dL; 95% credible interval, 0.13-4.32 mg/dL); cholesterol levels with quetiapine (10.77 +/- 2.14 mg/dL; 95% credible interval, 6.6-14.95 mg/dL) and olanzapine (4.46 +/- 1.65 mg/dL; 95% credible interval, 1.24-7.73 mg/dL); triglyceride levels with olanzapine (20.18 +/- 5.26 mg/dL; 95% credible interval, 9.85-30.53 mg/dL) and quetiapine (19.5 +/- 3.92 mg/dL; 95% credible interval, 11.84-27.17 mg/dL); hyperprolactinemia with risperidone (OR, 38.63; 95% credible interval, 8.62-125.6), olanzapine (OR, 15.6; 95% credible interval, 4.39-41.1), and ziprasidone (OR, 9.35; 95% credible interval, 1.24-37.03); and EPS with ziprasidone (OR, 20.56; 95% credible interval, 3.53-68.94), olanzapine (OR, 6.36; 95% credible interval, 2.43-13.84), aripiprazole (OR, 3.79; 95% credible interval, 2.17-6.17), and risperidone (OR, 3.71; 95% credible interval, 2.18-6.02). 

All SGAs increased the risk of somnolence/sedation. We conclude that short-term metabolic effects and EPS are frequent in children treated with SGAs. Second-generation antipsychotics have distinct profiles of secondary effects, which should be considered in making treatment decisions.
AD  - Cohen,David. Department of Child and Adolescent Psychiatry, Universite Pierre et Marie Curie, GH Pitie-Salpetriere, Paris, France. david.cohen@psl.aphp.fr
AN  - 22544019
AU  - Cohen,
AU  - D.
AU  - Bonnot,
AU  - O.
AU  - Bodeau,
AU  - N.
AU  - Consoli,
AU  - A.
AU  - Laurent,
AU  - C.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/JCP.0b013e3182549259.
DP  - Ovid Technologies
J2  - J Clin Psychopharmacol
KW  - Adolescent *Antipsychotic Agents/ae [Adverse Effects] Bayes Theorem Child Disorders of Excessive Somnolence/ci [Chemically Induced] Humans Hyperglycemia/ci [Chemically Induced] Hyperlipidemias/ci [Chemically Induced] Hyperprolactinemia/ci [Chemically In
L1  - internal-pdf://2212248018/Cohen-2012-Adverse effects of second-generatio.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Cohen, David Bonnot, Olivier Bodeau, Nicolas Consoli, Angele Laurent, Claudine Comment in: Evid Based Ment Health. 2012 Nov;15(4):100; PMID: 22956480
PY  - 2012
SP  - 309-16
T2  - Journal of Clinical Psychopharmacology
TI  - Adverse effects of second-generation antipsychotics in children and adolescents: a Bayesian meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22544019
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22544019&amp;id=doi:10.1097%2FJCP.0b013e3182549259&amp;issn=0271-0749&amp;isbn=&amp;volume=32&amp;issue=3&amp;spage=309&amp;pages=309-16&amp;date=2012&amp;title=Journal+of+Clinical+Psychopharmacology&amp;atitle=Adverse+effects+of+second-generation+antipsychotics+in+children+and+adolescents%3A+a+Bayesian+meta-analysis.&amp;aulast=Cohen&amp;pid=%3Cauthor%3ECohen+D%3C%2Fauthor%3E%3CAN%3E22544019%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://graphics.tx.ovid.com/ovftpdfs/FPDDNCLBMEJCKF00/fs047/ovft/live/gv024/00004714/00004714-201206000-00002.pdf
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCIBCHMNLI00/fs047/ovft/live/gv024/00004714/00004714-201206000-00002.pdf
VL  - 32
ER  -
TY  - JOUR
AB  - **Background **
Post-traumatic stress disorder (PTSD) is highly prevalent in children and adolescents who have experienced trauma and has high personal and health costs. Although a wide range of psychological therapies have been used in the treatment of PTSD there are no systematic reviews of these therapies in children and adolescents. 

**Objectives **
To examine the effectiveness of psychological therapies in treating children and adolescents who have been diagnosed with PTSD. 

**Search methods **
We searched the Cochrane Depression, Anxiety and Neurosis Review Group&#039;s Specialised Register (CCDANCTR) to December 2011. The CCDANCTR includes relevant randomised controlled trials from the following bibliographic databases: CENTRAL (the Cochrane Central Register of Controlled Trials) (all years), EMBASE (1974 -), MEDLINE (1950 -) and PsycINFO (1967 -). We also checked reference lists of relevant studies and reviews. We applied no date or language restrictions.

**Selection criteria **
All randomised controlled trials of psychological therapies compared to a control, pharmacological therapy or other treatments in children or adolescents exposed to a traumatic event or diagnosed with PTSD. Data collection and analysis Two members of the review group independently extracted data. If differences were identified, they were resolved by consensus, or referral to the review team. We calculated the odds ratio (OR) for binary outcomes, the standardised mean difference (SMD) for continuous outcomes, and 95% confidence intervals (CI) for both, using a fixed-effect model. If heterogeneity was found we used a random-effects model. 

**Main results**
Fourteen studies including 758 participants were included in this review. The types of trauma participants had been exposed to included sexual abuse, civil violence, natural disaster, domestic violence and motor vehicle accidents. Most participants were clients of a trauma-related support service. The psychological therapies used in these studies were cognitive behavioural therapy (CBT), exposure-based, psychodynamic, narrative, supportive counselling, and eye movement desensitisation and reprocessing (EMDR). Most compared a psychological therapy to a control group. No study compared psychological therapies to pharmacological therapies alone or as an adjunct to a psychological therapy. Across all psychological therapies, improvement was significantly better (three studies, n = 80, OR 4.21, 95% CI 1.12 to 15.85) and symptoms of PTSD (seven studies, n = 271, SMD -0.90, 95% CI -1.24 to -0.42), anxiety (three studies, n = 91, SMD -0.57, 95% CI -1.00 to -0.13) and depression (five studies, n = 156, SMD -0.74, 95% CI -1.11 to -0.36) were significantly lower within a month of completing psychological therapy compared to a control group. The psychological therapy for which there was the best evidence of effectiveness was CBT. Improvement was significantly better for up to a year following treatment (up to one month: two studies, n = 49, OR 8.64, 95% CI 2.01 to 37.14; up to one year: one study, n = 25, OR 8.00, 95% CI 1.21 to 52.69). PTSD symptom scores were also significantly lower for up to one year (up to one month: three studies, n = 98, SMD -1.34, 95% CI -1.79 to -0.89; up to one year: one study, n = 36, SMD -0.73, 95% CI -1.44 to -0.01), and depression scores were lower for up to a month (three studies, n = 98, SMD -0.80, 95% CI -1.47 to -0.13) in the CBT group compared to a control. No adverse effects were identified. No study was rated as a high risk for selection or detection bias but a minority were rated as a high risk for attrition, reporting and other bias. Most included studies were rated as an unclear risk for selection, detection and attrition bias. 

**Authors&#039; conclusions **
There is evidence for the effectiveness of psychological therapies, particularly CBT, for treating PTSD in children and adolescents for up to a month following treatment. At this stage, there is no clear evidence for the effectiveness of one psychological therapy compared to others. There is also not enough evidence to conclude that children and adolescents with particular types of trauma are more or less likely to respond to psychological therapies than others. The findings of this review are limited by the potential for methodological biases, and the small number and generally small size of identified studies. In addition, there was evidence of substantial heterogeneity in some analyses which could not be explained by subgroup or sensitivity analyses More evidence is required for the effectiveness of all psychological therapies more than one month after treatment. Much more evidence is needed to demonstrate the relative effectiveness of different psychological therapies or the effectiveness of psychological therapies compared to other treatments. More details are required in future trials in regards to the types of trauma that preceded the diagnosis of PTSD and whether the traumas are single event or ongoing. Future studies should also aim to identify the most valid and reliable measures of PTSD symptoms and ensure that all scores, total and sub-scores, are consistently reported.
AD  - [Gillies, Donna] Cumberland Hosp, Western Sydney &amp; Nepean Blue Mt Local Hlth Dist M, Parramatta, NSW 2150, Australia. [Taylor, Fiona] Sydney W Area Mental Hlth Serv, Prevent Early Intervent &amp; Recovery Serv, Parramatta, Australia. [Gray, Carl] New S Wales Hlth Serv, Western Sydney Local Hlth Network, Dept Child &amp; Adolescent Psychiat, Westmead, NSW, Australia. [O&#039;Brien, Louise] Univ Newcastle, Sch Nursing &amp; Midwifery, Orange, NSW, Australia. [O&#039;Brien, Louise] New S Wales Hlth Serv, Greater Western Area Hlth Serv, Orange, NSW, Australia. [D&#039;Abrew, Natalie] Univ Sydney, Sydney Sch Nursing, Canc Nursing Res Unit, Camperdown, NSW, Australia. [D&#039;Abrew, Natalie] Royal Prince Alfred Hosp, Sydney Canc Ctr, Camperdown, NSW 2050, Australia. Gillies, D (reprint author), Cumberland Hosp, Western Sydney &amp; Nepean Blue Mt Local Hlth Dist M, Locked Bag 7118, Parramatta, NSW 2150, Australia. Donna_Gillies@wsahs.nsw.gov.au
AN  - WOS:000312254600007
AU  - Gillies,
AU  - D.
AU  - Taylor,
AU  - F.
AU  - Gray,
AU  - C.
AU  - O&#039;
AU  - Brien,
AU  - L.
AU  - D&#039;
AU  - Abrew,
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD006726.pub2
J2  - Cochrane Database Syst Rev.
KW  - RANDOMIZED-CONTROLLED-TRIAL COGNITIVE-BEHAVIORAL THERAPY NARRATIVE EXPOSURE THERAPY ABUSED PRESCHOOL-CHILDREN ELEMENTARY-SCHOOL-CHILDREN MENTAL-HEALTH INTERVENTION INTIMATE PARTNER VIOLENCE FOLLOW-UP PSYCHOSOCIAL INTERVENTION PTSD SYMPTOMS Medicine, Gen
L1  - internal-pdf://3459255714/Gillies-2012-Psychological therapies for the t.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 053EV Times Cited: 3 Cited Reference Count: 142 Gillies, Donna Taylor, Fiona Gray, Carl O&#039;Brien, Louise D&#039;Abrew, Natalie Sydney West Area Health Service, Australia; University of Western Sydney, Australia Internal sourcesSydney West Area Health Service, Australia.The University of Western Sydney, Australia. 3 WILEY-BLACKWELL HOBOKEN COCHRANE DB SYST REV
PY  - 2012
SP  - 113
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological therapies for the treatment of post-traumatic stress disorder in children and adolescents
UR  - &lt;Go to ISI&gt;://WOS:000312254600007http://onlinelibrary.wiley.com/store/10.1002/14651858.CD006726.pub2/asset/CD006726.pdf?v=1&amp;t=ib7tfao8&amp;s=6e791f549073328aa13e8026aaaba91bdcb2a5fa
ER  -
TY  - JOUR
AB  - **Background:** 
Enuresis (bedwetting) is a socially stigmatising and stressful condition which affects around 15% to 20% of five-year olds and up to 2% of young adults. Although there is a high rate of spontaneous remission, the social, emotional and psychological costs to the children can be great. Drugs (including desmopressin, tricyclics and other drugs) have often been tried to treat nocturnal enuresis.

**Objectives:** 
To assess the effects of drugs other than desmopressin and tricyclics on nocturnal enuresis in children and to compare them with other interventions.

**Search methods:** 
We searched the Cochrane Incontinence Group Specialised Register of trials (searched 15 December 2011), which includes searches of MEDLINE and CENTRAL, to identify published and unpublished randomised and quasi-randomised trials. The reference lists of relevant articles were also searched.

**Selection criteria:** 
All randomised trials of drugs (excluding desmopressin or tricyclics) for treating nocturnal enuresis in children up to the age of 16 years were included in the review. Trials were eligible for inclusion if children were randomised to receive drugs compared with placebo, other drugs or behavioral interventions for nocturnal enuresis. Studies which included children with daytime urinary incontinence or children with organic conditions were also included in this review if the focus of the study was on nocturnal enuresis. Trials focused solely on daytime wetting and trials of adults with nocturnal enuresis were excluded.

**Data collection and analysis:** 
Two review authors independently assessed the quality of the eligible trials and extracted data. Differences between review authors were settled by discussion with a third review author.

**Main results:** 
A total of 40 randomised or quasi-randomised controlled trials (10 new in this update) met the inclusion criteria, with a total of 1780 out of 2440 children who enrolled receiving an active drug other than desmopressin or a tricyclic. In all, 31 different drugs or classes of drugs were tested. The trials were generally small or of poor methodological quality. There was an overall paucity of data regarding outcomes after treatment was withdrawn.For drugs versus placebo, when compared to placebo indomethacin (risk ratio [RR] 0.36, 95% CI 0.16 to 0.79), diazepam (RR 0.22, 95% CI 0.11 to 0.46), mestorelone (RR 0.32, 95% CI 0.17 to 0.62) and atomoxetine (RR 0.81, 95% CI 0.70 to 0.94) appeared to reduce the number of children failing to have 14 consecutive dry nights. Although indomethacin and diclofenac were better than placebo during treatment, they were not as effective as desmopressin and there was a higher chance of adverse effects. None of the medications were effective in reducing relapse rates, although this was only reported in five placebo controlled trials.For drugs versus drugs, combination therapy with imipramine and oxybutynin was more effective than imipramine monotherapy (RR 0.68, 95% CI 0.50 to 0.94) and also had significantly lower relapse rates than imipramine monotherapy (RR 0.35, 95% CI 0.16 to 0.77). There was an overall paucity of data regarding outcomes after treatment was withdrawn.For drugs versus behavioural therapy, bedwetting alarms were found to be better than amphetamine (RR 2.2, 95% CI 1.12 to 4.29), oxybutynin (RR 3.25, 95% CI 1.77 to 5.98), and oxybutynin plus holding exercises (RR 3.3, 95% CI 1.84 to 6.18) in reducing the number of children failing to achieve 14 consecutive dry nights.Adverse effects of drugs were seen in 19 trials while 17 trials did not adequately report the occurrence of side effects.

**Authors&#039; conclusions:** 
There was not enough evidence to judge whether or not the included drugs cured bedwetting when used alone. There was limited evidence to suggest that desmopressin, imipramine and enuresis alarms therapy were better than the included drugs to which they were compared. In other reviews, desmopressin, tricyclics and alarm interventions have been shown to be effective during treatment. There was also evidence to suggest that combination therapy with antich l nergic therapy increased the efficacy of other established therapies such as imipramine, desmopressin and enuresis alarms by reducing the relapse rates, by about 20%, although it was not possible to identify the characteristics of children who would benefit from combination therapy. Future studies should evaluate the role of combination therapy against established treatments in rigorous and adequately powered trials.
AN  - CD002238
AU  - Deshpande,
AU  - A.
AU  - V.
AU  - Caldwell,
AU  - P.
AU  - H.
AU  - Sureshkumar,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd002238.pub2
KW  - Anti-Inflammatory Agents, Non-Steroidal [therapeutic use]
KW  - Antidiuretic Agents [therapeutic use]
KW  - Cholinergic Antagonists [therapeutic use]
KW  - Clinical Alarms [adverse effects]
KW  - Drug Therapy, Combination [methods]
KW  - Nocturnal Enuresis [drug therapy] [prevention &amp; control]
KW  - Psychotropic Drugs [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Incont
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Drugs for nocturnal enuresis in children (other than desmopressin and tricyclics)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002238.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD002238.pub2/asset/CD002238.pdf?v=1&amp;t=iw7jaxrx&amp;s=c8945c06b2f9b0215431222520b52c1a02ef6c7c
ER  -
TY  - JOUR
AB  - **Background:** 
Depressive disorders are common in young people and are associated with significant negative impacts. Newer generation antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), are often used, however evidence of their effectiveness in children and adolescents is not clear. Furthermore, there have been warnings against their use in this population due to concerns about increased risk of suicidal ideation and behaviour.

**Objectives:** 
To determine the efficacy and adverse outcomes, including definitive suicidal behaviour and suicidal ideation, of newer generation antidepressants compared with placebo in the treatment of depressive disorders in children and adolescents.

**Search methods:**
For this update of the review, we searched the Cochrane Depression, Anxiety and Neurosis Review Group&#039;s Specialised Register (CCDANCTR) to October 2011. The CCDANCTR includes relevant randomised controlled trials from the following bibliographic databases: CENTRAL (the Cochrane Central Register of Controlled Trials) (all years), EMBASE (1974 -), MEDLINE (1950 -) and PsycINFO (1967 -). We searched clinical trial registries and pharmaceutical company websites. We checked reference lists of included trials and other reviews, and sent letters to key researchers and the pharmaceutical companies of included trials from January to August 2011.

**Selection criteria:**
Published and unpublished randomised controlled trials (RCTs), cross-over trials and cluster trials comparing a newer generation antidepressant with a placebo in children and adolescents aged 6 to 18 years old and diagnosed with a depressive disorder were eligible for inclusion. In this update, we amended the selection criteria to include newer generation antidepressants rather than SSRIs only.

**Data collection and analysis:** 
Two or three review authors selected the trials, assessed their quality, and extracted trial and outcome data. We used a random-effects meta-analysis. We used risk ratio (RR) to summarise dichotomous outcomes and mean difference (MD) to summarise continuous measures.

**Main results:** 
Nineteen trials of a range of newer antidepressants compared with placebo, containing 3335 participants, were included. The trials excluded young people at high risk of suicide and many co-morbid conditions and the participants are likely to be less unwell than those seen in clinical practice. We judged none of these trials to be at low risk of bias, with limited information about many aspects of risk of bias, high drop out rates and issues regarding measurement instruments and the clinical usefulness of outcomes, which were often variously defined across trials. Overall, there was evidence that those treated with an antidepressant had lower depression severity scores and higher rates of response/remission than those on placebo. However, the size of these effects was small with a reduction in depression symptoms of 3.51 on a scale from 17 to 113 (14 trials; N = 2490; MD -3.51; 95% confidence interval (CI) -4.55 to -2.47). Remission rates increased from 380 per 1000 to 448 per 1000 for those treated with an antidepressant. There was evidence of an increased risk (58%) of suicide-related outcome for those on antidepressants compared with a placebo (17 trials; N = 3229; RR 1.58; 95% CI 1.02 to 2.45). This equates to an increased risk in a group with a median baseline risk from 25 in 1000 to 40 in 1000. Where rates of adverse events were reported, this was higher for those prescribed an antidepressant. There was no evidence that the magnitude of intervention effects (compared with placebo) were modified by individual drug class.

**Authors&#039; conclusions:**
Caution is required in interpreting the results given the methodological limitations of the included trials in terms of internal and external validity. Further, the size and clinical meaningfulness of statistically significant results are uncertain. However, given the risks of untreated depression in terms of completed suicide and impacts on functioning, if a decision to use medication is agreed, then fluoxetine might be h medication of first choice given guideline recommendations. Clinicians need to keep in mind that there is evidence of an increased risk of suicide-related outcomes in those treated with antidepressant medications.
AN  - CD004851
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - McKenzie,
AU  - J.
AU  - E.
AU  - Cox,
AU  - G.
AU  - R.
AU  - Simmons,
AU  - M.
AU  - B.
AU  - Merry,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004851.pub3
KW  - Antidepressive Agents [adverse effects] [therapeutic use]
KW  - Citalopram [administration &amp; dosage] [therapeutic use]
KW  - Depressive Disorder [drug therapy] [psychology]
KW  - Fluoxetine [adverse effects] [therapeutic use]
KW  - Induction Chemotherapy
KW  - Paroxetine [adverse effects] [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Serotonin Uptake Inhibitors [adverse effects] [therapeutic use]
KW  - Sertraline [administration &amp; dosage] [therapeutic use]
KW  - Suicide [psychology]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Newer generation antidepressants for depressive disorders in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004851.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004851.pub3/asset/CD004851.pdf?v=1&amp;t=iw7k9zzs&amp;s=c16c97a2086ab7d920402a82eb82ec5b9dbf46af
ER  -
TY  - JOUR
AB  - **Issues.** 
To reduce the occurrence and costs related to substance use and associated harms it is important to intervene early. Although a number of international school-based prevention programs exist, the majority show minimal effects in reducing drug use and related harms. Given the emphasis on early intervention and prevention in Australia, it is timely to review the programs currently trialled in Australian schools. This paper reports the type and efficacy of Australian school-based prevention programs for alcohol and other drugs. 

**Approach.** 
Cochrane, PsychInfo and PubMed databases were searched. Additional materials were obtained from authors, websites and reference lists. Studies were selected if they described programs developed and trialled in Australia that address prevention of alcohol and other drug use in schools. 

**Key Findings.** 
Eight trials of seven intervention programs were identified. The programs targeted alcohol, cannabis and tobacco and most were based on social learning principles. All were universal. Five of the seven intervention programs achieved reductions in alcohol, cannabis and tobacco use at follow up. 

**Conclusion.** 
Existing school-based prevention programs have shown to be efficacious in the Australian context. However, there are only a few programs available, and these require further evaluative research. This is critical, given that substance use is such a significant public health problem. The findings challenge the commonly held view that school-based prevention programs are not effective.
AD  - [Teesson, Maree; Newton, Nicola C.; Barrett, Emma L.] Univ New S Wales, Natl Drug &amp; Alcohol Res Ctr, Sydney, NSW 2052, Australia. Teesson, M (reprint author), Univ New S Wales, Natl Drug &amp; Alcohol Res Ctr, Sydney, NSW 2052, Australia. m.teesson@unsw.edu.au
AN  - WOS:000308466400002
AU  - Teesson,
AU  - M.
AU  - Newton,
AU  - N.
AU  - C.
AU  - Barrett,
AU  - E.
AU  - L.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1465-3362.2012.00420.x
J2  - Drug Alcohol Rev.
KW  - alcohol drug prevention school-based adolescent RANDOMIZED CONTROLLED-TRIAL HARM MINIMIZATION YOUNG-PEOPLE CANNABIS USE EDUCATION SMOKING ABUSE INTERNET CHILDREN PROJECT Substance Abuse
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 001NC Times Cited: 11 Cited Reference Count: 42 Teesson, Maree Newton, Nicola C. Barrett, Emma L. 11 WILEY-BLACKWELL HOBOKEN DRUG ALCOHOL REV
PY  - 2012
SP  - 731-736
T2  - Drug and Alcohol Review
TI  - Australian school-based prevention programs for alcohol and other drugs: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000308466400002http://onlinelibrary.wiley.com/store/10.1111/j.1465-3362.2012.00420.x/asset/dar420.pdf?v=1&amp;t=ib7vowgr&amp;s=e9472c84bba329dcdd248aff12887cfbd3180a94
VL  - 31
ER  -
TY  - JOUR
AB  - **Background:** 
Preterm infants are at risk of exhausting their body iron stores much earlier than healthy term newborns. It is widespread practice to give enteral iron supplementation to preterm and low birth weight infants to prevent iron deficiency anaemia. However, it is unclear whether supplementing preterm and low birth weight infants with iron improves growth and neurodevelopment. It is suspected that excess exogenous iron can contribute to oxidative injury in preterm babies, causing or exacerbating conditions such as necrotising enterocolitis and retinopathy of prematurity. Additionally, the optimal dose and timing of commencement and cessation of iron supplementation are uncertain.

**Objectives:** 
To evaluate the effect of prophylactic enteral iron supplementation on growth and neurodevelopmental outcomes in preterm and low birth weight infants. The secondary objectives were to determine whether iron supplementation results in improved haematological parameters and prevents other causes of morbidity and mortality.

**Search methods:** 
We used the standard search strategy of the Cochrane Neonatal Review Group. We searched Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 8), MEDLINE (1951 to August 2011), CINAHL (1982 to August 2011) and conference proceedings and previous reviews.

**Selection criteria:** 
Randomised controlled trials (RCTs) and quasi-randomised trials that compared enteral iron supplementation with no iron supplementation, or different regimens of enteral iron supplementation in preterm or low birth weight infants or both.

**Data collection and analysis:** 
We extracted data using the standard methods of the Cochrane Neonatal Review Group. Both review authors separately evaluated trial quality and data extraction. We synthesised data using risk ratios (RRs), risk differences (RDs) and weighted mean differences (WMDs). Where data about the methodology and results or both were lacking, we made an attempt to contact the study authors for further information.

**Main results:** 
We included twenty-six studies (2726 infants) in the analysis. The heterogeneity of participants, methods and results precluded an extensive quantitative synthesis. Of the 21 studies comparing iron supplementation with controls, none evaluated neurodevelopmental status as an outcome. Of thirteen studies reporting at least one growth parameter as an outcome, only one study of poor quality found a significant benefit of iron supplementation. Regarding haematological outcomes, no benefit for iron supplementation was demonstrated within the first 8.5 weeks of postnatal life (16 trials), except by two poor quality studies. After this age, most studies reported a higher mean haemoglobin in iron-supplemented infants. We were only able to include a limited number of studies in a quantitative meta-analysis, which suggested the haemoglobin concentration in iron-supplemented infants was higher by about 6 g/L at six to nine months. One study comparing high dose and low dose iron supplementation monitored neurodevelopmental outcome for one year, without finding any significant difference between the groups. One study comparing early versus late commencement of iron supplementation found no difference in cognitive outcome, but an increased rate of abnormal neurological examination in the late iron group at five years of age. The studies comparing high and low doses of iron indicated that there was no discernible haematological benefit in exceeding &#039;standard&#039; doses of iron (i.e. 2 mg/kg/day to 3 mg/kg/day).

**Authors&#039; conclusions:** 
The available data suggest that infants who receive iron supplementation have a slightly higher haemoglobin level, improved iron stores and a lower risk of developing iron deficiency anaemia when compared with those who are unsupplemented. However, it is unclear whether iron supplementation in preterm and low birth weight infants has long term benefits in terms of neurodevelopmental outcome and growth. The optimum timing and duration of iron supplementation remains unclear.
AN  - CD005095
AU  - Mills,
AU  - R.
AU  - J.
AU  - Davies,
AU  - M.
AU  - W.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd005095.pub2
KW  - Dietary Supplements
KW  - Child Development [drug effects] [physiology]
KW  - Enteral Nutrition
KW  - Erythrocytes [cytology] [drug effects]
KW  - Hemoglobin A [metabolism]
KW  - Infant, Low Birth Weight [blood] [growth &amp; development]
KW  - Infant, Newborn
KW  - Infant, Premature [blood] [growth &amp; development]
KW  - Iron [administration &amp; dosage] [blood]
KW  - Randomized Controlled Trials as Topic
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Neonatal
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Enteral iron supplementation in preterm and low birth weight infants
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005095.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005095.pub2/asset/CD005095.pdf?v=1&amp;t=iw7je8o6&amp;s=48b89999ce85a3a852e5400b842c3034a2d2c4d3
ER  -
TY  - JOUR
AB  - **Background **
Despite differences in how it is defined, there is a general consensus amongst clinicians and researchers that the sexual abuse of children and adolescents (&#039;child sexual abuse&#039;) is a substantial social problem worldwide. The effects of sexual abuse manifest in a wide range of symptoms, including fear, anxiety, post-traumatic stress disorder and various externalising and internalising behaviour problems, such as inappropriate sexual behaviours. Child sexual abuse is associated with increased risk of psychological problems in adulthood. Cognitive-behavioural approaches are used to help children and their non-offending or &#039;safe&#039; parent to manage the sequelae of childhood sexual abuse. This review updates the first Cochrane review of cognitive-behavioural approaches interventions for children who have been sexually abused, which was first published in 2006. 

**Objectives **
To assess the efficacy of cognitive-behavioural approaches (CBT) in addressing the immediate and longer-term sequelae of sexual abuse on children and young people up to 18 years of age. Search methods We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (2011 Issue 4); MEDLINE (1950 to November Week 3 2011); EMBASE (1980 to Week 47 2011); CINAHL (1937 to 2 December 2011); PsycINFO (1887 to November Week 5 2011); LILACS (1982 to 2 December 2011) and OpenGrey, previously OpenSIGLE (1980 to 2 December 2011). For this update we also searched ClinicalTrials.gov and the International Clinical Trials Registry Platform (ICTRP). 

**Selection criteria **
We included randomised or quasi-randomised controlled trials of CBT used with children and adolescents up to age 18 years who had experienced being sexually abused, compared with treatment as usual, with or without placebo control. 

**Data collection and analysis **
At least two review authors independently assessed the eligibility of titles and abstracts identified in the search. Two review authors independently extracted data from included studies and entered these into Review Manager 5 software. We synthesised and presented data in both written and graphical form (forest plots). 

**Main results **
We included 10 trials, involving 847 participants. All studies examined CBT programmes provided to children or children and a non-offending parent. Control groups included wait list controls (n = 1) or treatment as usual (n = 9). Treatment as usual was, for the most part, supportive, unstructured psychotherapy. Generally the reporting of studies was poor. Only four studies were judged &#039;low risk of bias&#039; with regards to sequence generation and only one study was judged &#039;low risk of bias&#039; in relation to allocation concealment. All studies were judged &#039;high risk of bias&#039; in relation to the blinding of outcome assessors or personnel; most studies did not report on these, or other issues of bias. Most studies reported results for study completers rather than for those recruited. Depression, post-traumatic stress disorder (PTSD), anxiety and child behaviour problems were the primary outcomes. Data suggest that CBT may have a positive impact on the sequelae of child sexual abuse, but most results were not statistically significant. Strongest evidence for positive effects of CBT appears to be in reducing PTSD and anxiety symptoms, but even in these areas effects tend to be &#039;moderate&#039; at best. Meta-analysis of data from five studies suggested an average decrease of 1.9 points on the Child Depression Inventory immediately after intervention (95% confidence interval (CI) decrease of 4.0 to increase of 0.4; I-2 = 53%; P value for heterogeneity = 0.08), representing a small to moderate effect size. Data from six studies yielded an average decrease of 0.44 standard deviations on a variety of child post-traumatic stress disorder scales (95% CI 0.16 to 0.73; I-2 = 46%; P value for heterogeneity = 0.10). Combined data from five studies yielded an average decrease of 0.23 standard deviations on various child anxiety scales (95% CI 0.3 to 0.4; I-2 = 0%; P value for heterogeneity = 0.84). No study reported adverse effects. 

**Authors&#039; conclusions **
The conclusions of this updated review remain the same as those when it was first published. The review confirms the potential of CBT to address the adverse consequences of child sexual abuse, but highlights the limitations of the evidence base and the need for more carefully conducted and better reported trials.
AD  - [Macdonald, Geraldine] Queens Univ Belfast, Sch Sociol Social Policy &amp; Social Work, Inst Child Care Res, Belfast BT7 1LP, Antrim, North Ireland. [Higgins, Julian P. T.] MRC Biostat Unit, Cambridge, England. [Ramchandani, Paul] Univ Oxford, Dept Psychiat, Oxford, England. [Valentine, Jeffrey C.] Univ Louisville, Dept Educ &amp; Counseling Psychol, Louisville, KY 40292 USA. [Bronger, Latricia P.; Klein, Paul; Pickering, Mark; Rademaker, Ben; Taylor, Matthew] Univ Louisville, Dept Teaching &amp; Learning, Louisville, KY 40292 USA. [O&#039;Daniel, Roland] Collaborat Teaching &amp; Learning, Louisville, KY USA. [Richardson, George] Univ Cincinnati, Sch Human Serv, Cincinnati, OH USA. Macdonald, G (reprint author), Queens Univ Belfast, Sch Sociol Social Policy &amp; Social Work, Inst Child Care Res, 6 Coll Pk, Belfast BT7 1LP, Antrim, North Ireland. Geraldine.Macdonald@qub.ac.uk
AN  - WOS:000304098900009
AU  - Macdonald,
AU  - G.
AU  - Higgins,
AU  - J.
AU  - P.
AU  - T.
AU  - Ramchandani,
AU  - P.
AU  - Valentine,
AU  - J.
AU  - C.
AU  - Bronger,
AU  - L.
AU  - P.
AU  - Klein,
AU  - P.
AU  - O&#039;
AU  - Daniel,
AU  - R.
AU  - Pickering,
AU  - M.
AU  - Rademaker,
AU  - B.
AU  - Richardson,
AU  - G.
AU  - Taylor,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD001930.pub2
J2  - Cochrane Database Syst Rev.
KW  - Cognitive Therapy Child Abuse, Sexual [psychology therapy] Randomized Controlled Trials as Topic Adolescent Child Child, Preschool Female Humans Infant Male POSTTRAUMATIC STRESS SYMPTOMS RANDOMIZED CONTROLLED-TRIAL 1-YEAR FOLLOW-UP PRESCHOOL-CHILDREN PT
L1  - internal-pdf://3143818868/Macdonald-2012-Cognitive-behavioural intervent.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 943CU Times Cited: 3 Cited Reference Count: 103 Macdonald, Geraldine Higgins, Julian P. T. Ramchandani, Paul Valentine, Jeffrey C. Bronger, Latricia P. Klein, Paul O&#039;Daniel, Roland Pickering, Mark Rademaker, Ben Richardson, George Taylor, Matthew Higgins, Julian/H-4008-2011; Ramchandani, Paul/O-5340-2014 Ramchandani, Paul/0000-0003-3646-2410 Northern Ireland Research Developmen, UK; Nordic Campbell Center, Denmark; Nordic Campbell Centre External sourcesNorthern Ireland Research &amp; Developmen, UK.Nordic Campbell Center, Denmark.Julian PT Higgins - received a payment from the Nordic Campbell Centre for his work on the first version of this review in 2006. 3 WILEY-BLACKWELL HOBOKEN COCHRANE DB SYST REV
PY  - 2012
SP  - 72
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive-behavioural interventions for children who have been sexually abused
UR  - &lt;Go to ISI&gt;://WOS:000304098900009http://onlinelibrary.wiley.com/store/10.1002/14651858.CD001930.pub3/asset/CD001930.pdf?v=1&amp;t=ib7u0qsv&amp;s=a958fd21f594ca45f359c6ddd4c01788991c5940
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
WE CONDUCTED A SYSTEMATIC REVIEW TO ANSWER THE QUESTION: Among youth &lt;18 years of age with a mental disorder, does substance use prevention compared to no prevention result in reduced rates of substance use/abuse/disorder (SUD)? 

The review was requested by the Ontario Ministry of Health and Long-term Care through the Canadian Institutes for Health Research Evidence on Tap program. 

**METHODS: **
A four-step search process was used: Search 1 and 2: Randomized controlled trials (RCTs) that evaluated a SUD prevention intervention in individuals with a mental disorder who were: 1) &lt;18 years; or, 2) any age. Search 3: Observational studies of an intervention to prevent SUD in those with mental disorder. Search 4: RCTs that evaluated a SUD primary prevention skills-based intervention in high-risk youth &lt;18 years. 

**RESULTS: **
Searches 1 and 2: one RCT conducted in youth was found; Search 3: two observational studies were found. All three studies reported statistically significant reductions in substance use. Search 4: five RCTs were found with mixed results. Methodological weaknesses including inadequate study power may explain the results. 

**CONCLUSIONS: **
Little is known about effective interventions to prevent SUD in youth with a mental disorder. Effective SUD primary prevention programs exist and should be evaluated in this high-risk group.
AD  - Salvo,Nadia. McMaster University, Hamilton, Ontario.
AN  - 23133458
AU  - Salvo,
AU  - N.
AU  - K.
AU  - Bennett,
AU  - K.
AU  - A.
AU  - Cheung,
AU  - A.
AU  - Y.
AU  - Chen,
AU  - Y.
AU  - M.
AU  - Rice,
AU  - M.
AU  - B.
AU  - Rush,
AU  - B.
AU  - H.
AU  - Bullock,
AU  - H.
AU  - A.
AU  - Bowlby,
AU  - A.
AU  - Evidence
AU  - on
AU  - Tap
AU  - Concurrent
AU  - Disorders
AU  - Collaborative
AU  - Team
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490525/
DP  - Ovid Technologies
J2  - J Can Acad Child Adolesc Psychiatry
L1  - internal-pdf://1386864124/Salvo-2012-Prevention of substance use in chil.pdf
LA  - English
N1  - Salvo, Nadia Bennett, Kathryn Cheung, Amy Chen, Yvonne Rice, Maureen Rush, Brian Bullock, Heather Bowlby, Anne Evidence on Tap Concurrent Disorders Collaborative Team
PY  - 2012
SP  - 245-52
T2  - Journal of the Canadian Academy of Child and Adolescent Psychiatry
TI  - Prevention of substance use in children/adolescents with mental disorders: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=23133458 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23133458&amp;id=doi:&amp;issn=1719-8429&amp;isbn=&amp;volume=21&amp;issue=4&amp;spage=245&amp;pages=245-52&amp;date=2012&amp;title=Journal+of+the+Canadian+Academy+of+Child+%26+Adolescent+Psychiatry+%3D+Journal+de+l.Acade.mie+canadienne+de+psychiatrie+de+l.enfant+et+de+l.adolescent&amp;atitle=Prevention+of+substance+use+in+children%2Fadolescents+with+mental+disorders%3A+a+systematic+review.&amp;aulast=Salvo&amp;pid=%3Cauthor%3ESalvo+N%3C%2Fauthor%3E%3CAN%3E23133458%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490525/pdf/ccap21_4p245.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490525/pdf/ccap21_4p245.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
Many, if not most, incarcerated offenders have substance abuse problems. Without effective treatment, these substance-abusing offenders are likely to persist in non-drug offending. The period of incarceration offers an opportunity to intervene in the cycle of drug abuse and crime. Although many types of incarceration-based drug treatment programs are available (e.g., therapeutic communities and group counseling), the effectiveness of these programs is unclear. 

**OBJECTIVES**
The objective of this research synthesis is to systematically review quasi-experimental and experimental (RCT) evaluations of the effectiveness of incarceration-based drug treatment programs in reducing post-release recidivism and drug relapse. A secondary objective of this synthesis is to examine variation in effectiveness by programmatic, sample, and methodological features. In this update of the original 2006 review (see Mitchell, Wilson, and MacKenzie, 2006), studies made available since the original review were included in an effort to keep current with emerging research. 

**SEARCH STRATEGY** 
We searched bibliographic databases, hand searched select journals, and reviewed websites of several research organizations involved in drug treatment research to identify potentially eligible studies. 

**SEARCH CRITERIA** 
Eligible studies needed to assess the effectiveness of incarceration-based (e.g., jail, prison) drug treatment programs, use experimental or quasi-experimental comparison group research designs, measured a post-release recidivism or drug use outcome, and be conducted between 1980 and 2011, inclusive. 

**DATA COLLECTION AND ANALYSIS**
From each evaluation, we coded an effect size that quantified each program&rsquo;s effect on various measures of recidivism and/or drug relapse. We also coded features of the program, research methodology, and sample. We analyzed effect sizes using the random-effects inverse-variance weight method of meta-analysis. 

**MAIN RESULTS** 
Seventy-four evaluations met our eligibility criteria. The overall average effect of these programs was approximately a 15 to 17% reduction in recidivism and drug relapse. The effectiveness of such programs, however, varied by program type. Therapeutic communities had relatively consistent but modest reductions in recidivism and drug relapse. Counseling and narcotic maintenance programs had mixed effects. Specifically, counseling programs on average reduced recidivism but not drug relapse, narcotic maintenance programs had sizeable reductions in drug relapse but not recidivism, and boot camps had negligible effects on both recidivism and drug relapse. 

**CONCLUSIONS** 
This synthesis of evaluations of incarceration-based drug treatment programs found that such programs are modestly effective in reducing recidivism. These findings most strongly support the effectiveness of therapeutic communities, as these programs produced relatively consistent reductions in recidivism and drug use. Both counseling and incarceration-based narcotic maintenance programs had mixed effects. Counseling programs were associated with reductions in recidivism but not drug use; whereas, incarceration-based narcotic maintenance programs were associated with reductions in drug use but not recidivism. Note that our findings regarding the effectiveness of incarceration-based narcotic maintenance programs differ from a larger review of community-based narcotic maintenance programs (see Egli, Pina, Christensen, Aebi, and Killias, 2009). Finally, boot camp programs for drug offenders had negligible effects on both recidivism and drug use.
AU  - Mitchell,
AU  - O.
AU  - MacKenzie,
AU  - D.
AU  - Wilson,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2012.18
KW  - Crime
KW  - Prisons
KW  - Prisoners
KW  - Substance dependence
KW  - Drug abuse
PY  - 2012
T2  - Campbell Systematic Reviews
TI  - The Effectiveness of Incarceration-Based Drug Treatment on Criminal Behavior: A Systematic Review
ER  -
TY  - JOUR
AB  - **Background:** 
Attention deficit hyperactivity disorder (ADHD) is a major problem in children and adolescents, characterised by age-inappropriate levels of inattention, hyperactivity and impulsivity, and is associated with long-term social, academic and mental health problems. The stimulant medications methylphenidate and amphetamine are the most frequently used treatments for ADHD, but these are not always effective and can be associated with side effects. Clinical and biochemical evidence suggests that deficiencies of polyunsaturated fatty acids (PUFA) could be related to ADHD. Children and adolescents with ADHD have been shown to have significantly lower plasma and blood concentrations of PUFA and, in particular, lower levels of omega-3 PUFA.&nbsp;These findings suggest that PUFA supplementation may reduce the attention and behaviour problems associated with ADHD.

**Objectives:** 
To compare the efficacy of PUFA to other forms of treatment or placebo in treating the symptoms of ADHD in children and adolescents.

**Search methods:** 
We searched the following databases in August 2011: CENTRAL (The Cochrane Library 2011, Issue 2), MEDLINE (1948 to July Week 3, 2011), EMBASE (1980 to 2011 Week 29), PsycINFO (1806 to current), CINAHL (1937 to current), BIOSIS (1969 to 30 July 2011), Science Citation Index (1970 to 30 July 2011), Social Science Citation Index (1970 to 30 July 2011), Conference Proceedings Citation Index - Science (1990 to 30 July 2011), Conference Proceedings Citation Index - Social Science and Humanities (1990 to 30 July 2011), Cochrane Database of Systematic Reviews (2011, Issue 7), DARE (2011 Issue 2), Dissertation Abstracts (via Dissertation Express) and the metaRegister of Controlled Trials (mRCT). In addition, we searched the following repositories for theses on 2 August 2011: DART, NTLTD and TROVE. We also checked reference lists of relevant studies and reviews for additional references.

**Selection criteria:**
Two review authors independently assessed the results of the database searches. We resolved any disagreements regarding the selection of studies through consensus or, if necessary, by consultation with a third member of the review team.

**Data collection and analysis:** 
Two members of the review team independently extracted details of participants and setting, interventions, methodology and outcome data. If differences were identified, we resolved them by consensus or referral to a third member of the team. We made all reasonable attempts to contact the authors where further clarification or missing data were needed.

**Main results:** 
We included 13 trials with 1011 participants in the review. After screening 366 references, we considered 23 relevant and obtained the full text for consideration. We excluded five papers and included 18 papers describing the 13 trials.&nbsp;Eight of the included trials had a parallel design: five compared an omega-3 PUFA supplement to placebo; two compared a combined omega-3 and omega-6 supplement to placebo, and one compared an omega-3 PUFA to a dietary supplement. Five of the included trials had a cross-over design: two compared combined omega-3/6 PUFA to placebo; two compared omega-6 PUFA with placebo; one compared omega-3 to omega-6 PUFA, and one compared omega-6 PUFA to dexamphetamine. Supplements were given for a period of between four and 16 weeks.There was a significantly higher likelihood of improvement in the group receiving omega-3/6 PUFA compared to placebo (two trials, 97 participants; risk ratio (RR) 2.19, 95% confidence interval (CI) 1.04 to 4.62). However, there were no statistically significant differences in parent-rated ADHD symptoms (five trials, 413 participants; standardised mean difference (SMD) -0.17, 95% CI -0.38 to 0.03); inattention (six trials, 469 participants; SMD -0.04, 95% CI -0.29 to 0.21) or hyperactivity/impulsivity (five trials, 416 participants; SMD -0.04, 95% CI -0.25 to 0.16) when all participants receiving PUFA supplements were compared to those receiving placebo.There were no statistically significant differences in teacher ratings of overall ADHD sympt m (four trials, 324 participants; SMD 0.05, 95% CI -0.18 to 0.27); inattention (three trials, 260 participants; SMD 0.26, 95% CI -0.22 to 0.74) or hyperactivity/impulsivity (three trials, 259 participants; SMD 0.10, 95% CI -0.16 to 0.35).There were also no differences between groups in behaviour, side effects or loss to follow-up.Overall, there were no other differences between groups for any other comparison.

**Authors&#039; conclusions:** 
Overall, there is little evidence that PUFA supplementation provides any benefit for the symptoms of ADHD in children and adolescents. The majority of data showed no benefit of PUFA supplementation, although there were some limited data that did show an improvement with combined omega-3 and omega-6 supplementation.It is important that future research addresses current weaknesses in this area, which include small sample sizes, variability of selection criteria, variability of the type and dosage of supplementation, short follow-up times and other methodological weaknesses.
AN  - CD007986
AU  - Gillies,
AU  - D.
AU  - Sinn,
AU  - J.
AU  - K.
AU  - Lad,
AU  - S.
AU  - S.
AU  - Leach,
AU  - M.
AU  - J.
AU  - Ross,
AU  - M.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007986.pub2
KW  - Dietary Supplements
KW  - Attention Deficit Disorder with Hyperactivity [drug therapy]
KW  - Fatty Acids, Omega-3 [administration &amp; dosage]
KW  - Fatty Acids, Omega-6 [administration &amp; dosage]
KW  - Fatty Acids, Unsaturated [administration &amp; dosage]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Behav
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Polyunsaturated fatty acids (PUFA) for attention deficit hyperactivity disorder (ADHD) in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007986.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007986.pub2/asset/CD007986.pdf?v=1&amp;t=iw7kp10o&amp;s=9b9af99b8d557f31cc2554d06af9a7d4cece9402
ER  -
TY  - JOUR
AB  - **CONTEXT: **
Adolescence marks a time when many young people engage in risky behaviors with potential implications for long-term health. Interventions focused on adolescents&#039; parents and other caregivers have the potential to affect adolescents across a variety of risk and health-outcome areas. 

**EVIDENCE ACQUISITION: **
Community Guide methods were used to evaluate the effectiveness of caregiver-targeted interventions in addressing adolescent risk and protective behaviors and health outcomes. Sixteen studies published during the search period (1966-2007) met review requirements and were included in this review. 

**EVIDENCE SYNTHESIS: **
Effectiveness was assessed based on changes in whether or not adolescents engaged in specified risk and protective behaviors; frequency of risk and protective behaviors, and health outcomes, also informed the results. Results from qualifying studies provided sufficient evidence that interventions delivered person-to-person (i.e., through some form of direct contact rather than through other forms of contact such as Internet or paper) and designed to modify parenting skills by targeting parents and other caregivers are effective in improving adolescent health. 

**CONCLUSIONS: **
Interventions delivered to parents and other caregivers affect a cross-cutting array of adolescent risk and protective behaviors to yield improvements in adolescent health. Analysis from this review forms the basis of the recommendation by the Community Preventive Services Task Force presented elsewhere in this issue.

Copyright Published by Elsevier Inc.
AD  - Burrus,Barri. RTI International, Research Triangle Park, North Carolina, USA.
AN  - 22341170
AU  - Burrus,
AU  - B.
AU  - Leeks,
AU  - K.
AU  - D.
AU  - Sipe,
AU  - T.
AU  - A.
AU  - Dolina,
AU  - S.
AU  - Soler,
AU  - R.
AU  - Elder,
AU  - R.
AU  - Barrios,
AU  - L.
AU  - Greenspan,
AU  - A.
AU  - Fishbein,
AU  - D.
AU  - Lindegren,
AU  - M.
AU  - L.
AU  - Achrekar,
AU  - A.
AU  - Dittus,
AU  - P.
AU  - Community
AU  - Preventive
AU  - Services
AU  - Task
AU  - Force
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.amepre.2011.12.001
DP  - Ovid Technologies
J2  - Am J Prev Med
KW  - Adolescent *Adolescent Behavior/px [Psychology] Caregivers/px [Psychology] Community Health Services/og [Organization &amp; Administration] *Health Behavior Humans Outcome Assessment (Health Care) Parenting/px [Psychology] *Parents/px [Psychology] Preventiv
LA  - English
M3  - Review
N1  - Burrus, Barri Leeks, Kimberly D Sipe, Theresa Ann Dolina, Suzanne Soler, Robin Elder, Randy Barrios, Lisa Greenspan, Arlene Fishbein, Dan Lindegren, Mary Lou Achrekar, Angeli Dittus, Patricia Community Preventive Services Task Force
PY  - 2012
SP  - 316-26
T2  - American Journal of Preventive Medicine
TI  - Person-to-person interventions targeted to parents and other caregivers to improve adolescent health: a community guide systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22341170
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22341170&amp;id=doi:10.1016%2Fj.amepre.2011.12.001&amp;issn=0749-3797&amp;isbn=&amp;volume=42&amp;issue=3&amp;spage=316&amp;pages=316-26&amp;date=2012&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=Person-to-person+interventions+targeted+to+parents+and+other+caregivers+to+improve+adolescent+health%3A+a+community+guide+systematic+review.&amp;aulast=Burrus&amp;pid=%3Cauthor%3EBurrus+B%3C%2Fauthor%3E%3CAN%3E22341170%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0749379711009196/1-s2.0-S0749379711009196-main.pdf?_tid=a8d64f1a-167e-11e5-8ff2-00000aab0f02&amp;acdnat=1434717075_6654bddeb9b51817bec808f2d3a6d83d
VL  - 42
ER  -
TY  - JOUR
AB  - The purpose of this review was to synthesize the research underlying group contingency interventions to determine whether there is sufficient evidence to support their use for managing the classroom behavior of students with behavioral difficulties. 

An application of the What Works Clearinghouse (WWC) procedures for evaluating single-subject research revealed that the research investigating group contingencies demonstrated sufficient rigor, evidence, and replication to label the intervention as evidence-based. 

These findings were further supported across five quantitative indices of treatment effect. The results associated with the application of the WWC procedures and quantitative evaluations were supplemented with additional systematic coding of methodological features and study characteristics to evaluate the populations and conditions under which the effects of the group contingency best generalize. 

Findings associated with this coding revealed that the lack of detailed reporting across studies limited our ability to determine for whom and under what conditions group contingencies are best suited. 

(C) 2012 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.
AD  - [Maggin, Daniel M.] Univ Illinois, Dept Special Educ, Chicago, IL 60607 USA. [Johnson, Austin H.; Chafouleas, Sandra M.; Ruberto, Laura M.; Berggren, Melissa] Univ Connecticut, Storrs, CT USA. Maggin, DM (reprint author), Univ Illinois, Dept Special Educ, 1040 W Harrison St,M-C 147, Chicago, IL 60607 USA. dmaggin@uic.edu
AN  - WOS:000310818400007
AU  - Maggin,
AU  - D.
AU  - M.
AU  - Johnson,
AU  - A.
AU  - H.
AU  - Chafouleas,
AU  - S.
AU  - M.
AU  - Ruberto,
AU  - L.
AU  - M.
AU  - Berggren,
AU  - M.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jsp.2012.06.001
J2  - J. Sch. Psychol.
KW  - Classroom management Evidence-based practice Quantitative synthesis Group contingency Single-subject Systematic review SINGLE-SUBJECT RESEARCH INDEPENDENT GROUP CONTINGENCIES DISRUPTIVE BEHAVIOR CLASSROOM-BEHAVIOR MIDDLE SCHOOL QUANTITATIVE SYNTHESIS AG
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 033RL Times Cited: 12 Cited Reference Count: 72 Maggin, Daniel M. Johnson, Austin H. Chafouleas, Sandra M. Ruberto, Laura M. Berggren, Melissa 12 PERGAMON-ELSEVIER SCIENCE LTD OXFORD J SCHOOL PSYCHOL
PY  - 2012
SP  - 625-654
T2  - Journal of School Psychology
TI  - A systematic evidence review of school-based group contingency interventions for students with challenging behavior
UR  - &lt;Go to ISI&gt;://WOS:000310818400007http://ac.els-cdn.com/S0022440512000660/1-s2.0-S0022440512000660-main.pdf?_tid=118b4cf6-1678-11e5-935a-00000aab0f02&amp;acdnat=1434714245_9b44239e8fc2c99579d768e2478a994d
VL  - 50
ER  -
TY  - JOUR
AB  - A meta-analysis evaluating the effects of school-based interventions for students with attention deficit hyperactivity disorder was conducted by examining 60 outcome studies between 1996 and 2010 that yielded 85 effect sizes. 

Separate analyses were performed for studies employing between-subjects, within- subjects, and single-subject experimental designs. The overall mean effect sizes for dependent measures of behavior were positive and significant for within-subjects (0.72) and single-subject (2.20) designs, but not for between-subjects (0.18) designs. 

Mean effect sizes for academic outcomes were positive but not significant for between-subjects (0.43) and within-subjects (0.42) design studies, but were positive and significant for single-subject (3.48) design studies. 

Contingency management, academic intervention, and cognitive-behavioral intervention strategies were all associated with positive effects for academic and behavioral outcomes. 

Other moderators (e.g., school setting, publication status) are discussed along with implications for school-based management of students with attention deficit hyperactivity disorder and future treatment studies for this population. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - DuPaul, George J.: gjd3@lehigh.edu DuPaul, George J.: Lehigh University, College of Education, 111 Research Drive, Bethlehem, PA, US, 18015, gjd3@lehigh.edu DuPaul, George J.: Lehigh University, Bethlehem, PA, US Eckert, Tanya L.: Syracuse University, Syracuse, NY, US Vilardo, Brigid: Lehigh University, Bethlehem, PA, US
AN  - 2012-34477-002
AU  - DuPaul,
AU  - G.
AU  - J.
AU  - Eckert,
AU  - T.
AU  - L.
AU  - Vilardo,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Har ikke DOI: https://eric.ed.gov/
DP  - Ovid Technologies
KW  - school based interventions, attention deficit hyperactivity disorder, academic outcomes, cognitive behavioral intervention *Academic Achievement *Attention Deficit Disorder with Hyperactivity *Cognitive Behavior Therapy *School Based Intervention Specia
LA  - English
M3  - Meta Analysis
PY  - 2012
SP  - 387-412
T2  - School Psychology Review
TI  - The effects of school-based interventions for attention deficit hyperactivity disorder: A meta-analysis 1996-2010
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc9&amp;AN=2012-34477-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=0279-6015&amp;isbn=&amp;volume=41&amp;issue=4&amp;spage=387&amp;pages=387-412&amp;date=2012&amp;title=School+Psychology+Review&amp;atitle=The+effects+of+school-based+interventions+for+attention+deficit+hyperactivity+disorder%3A+A+meta-analysis+1996-2010.&amp;aulast=DuPaul&amp;pid=%3Cauthor%3EDuPaul%2C+George+J%3C%2Fauthor%3E%3CAN%3E2012-34477-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 41
ER  -
TY  - JOUR
AB  - Drug courts are specialized courts in which court actors collaboratively use the legal and moral authority of the court to monitor drug-involved offenders&rsquo; abstinence from drug use via frequent drug testing and compliance with individualized drug treatment programs. The objective of this review was to systematically review quasi-experimental and experimental evaluations of the effectiveness of drug courts in reducing future offending and drug use. The systematic search identified 154 independent, eligible evaluations, 92 evaluations of adult drug courts, 34 of juvenile drug courts, and 28 of drunk-driving (DWI) drug courts. The findings most strongly support the effectiveness of adult drug courts, as even the most rigorous evaluations consistently find reductions in recidivism and these effects generally persist for at least three years. The magnitude of this effect is analogous to a drop in general and drug-related recidivism from 50% for non-participants to approximately 38% for participants. The evidence also suggests that DWI drug courts are effective in reducing recidivism and their effect on recidivism is very similar in magnitude to that of adult drug courts (i.e., a reduction in recidivism of approximately 12 percentage points); yet, some caution is warranted, as the few available experimental evaluations of DWI drug courts do not uniformly support their effectiveness. For juvenile drug courts we find considerably smaller effects on recidivism. The mean effect size for these courts is analogous to a drop in recidivism from 50% for non-participants to roughly 43.5% for participants.
AU  - Mitchell,
AU  - O.
AU  - Wilson,
AU  - D.
AU  - Eggers,
AU  - A.
AU  - MacKenzie,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2012.4
KW  - Drug abuse
KW  - Adults
KW  - Offenders
KW  - Sentencing
KW  - Administration of justice
KW  - Drug abuse counselling
KW  - Substance abuse
KW  - Drug psychotherapy
KW  - Drug education
KW  - Crime reduction
KW  - Crime
PY  - 2012
T2  - Campbell Systematic Reviews
TI  - Drug Courts&#039; Effects on Criminal Offending for Juveniles and Adults
ER  -
TY  - JOUR
AB  - **Background:** 
Zinc deficiency is a significant public health problem in low- and middle-income countries. Zinc is essential for the formation and migration of neurons along with the formation of neuronal synapses. Its deficiency could interfere with the formation of neural pathways and with neurotransmission, thus affecting behavior (for example, attention, activity, engagement, temperament) and development (for example, gross and fine motor skills, social skills). Zinc supplementation provided to infants and children is a possible strategy to improve the mental and motor development of infants and children at high risk of zinc deficiency.

**Objectives:** 
To assess the effects of zinc supplementation compared to placebo on measures of psychomotor development or cognitive function in children.

**Search methods:** 
We searched MEDLINE, PsycINFO, CINAHL and Latin American Database (LILACS) on 1 December 2011. We searched EMBASE and CENTRAL 2011 Issue 12 on 19 January 2012. We searched Dissertation Abstracts International and the metaRegister of Controlled Trials on 30 November 2011.

**Selection criteria:** 
Randomized or quasi-randomized placebo-controlled trials involving synthetic zinc supplementation provided to infants or children (less than five years of age) were eligible.

**Data collection and analysis:** 
Two review authors screened search results, selected studies, assessed the studies for their risk of bias and extracted data.

**Main results:** 
We included 13 trials in this review.Eight studies reported data on the Bayley Scales of Infant Development (BSID) in 2134 participants. We combined the data in a meta-analysis to assess the effect on development as measured by the Mental Development Index (MDI) and Psychomotor Development Index (PDI). There was no significant effect of zinc supplementation: the mean difference between the zinc supplementation and placebo groups on the MDI was -0.50 (95% confidence interval (CI) -2.06 to 1.06; P = 0.53; I2 = 70%) and the mean difference between the groups for the PDI was&nbsp;1.54 (95% CI -2.26 to 5.34; P = 0.43; I2 = 93%). Most studies had low or unclear risk of bias but there was significant heterogeneity, which was not adequately explained by our subgroup analyses. The overall quality of evidence was considered &#039;moderate&#039;.Two trials provided data on motor milestone attainment. There was no significant difference in the time to attainment of milestones between the placebo group and the zinc supplementation group in either of the studies.No study provided data on cognition score or intelligence quotient (IQ) or on adverse effects of zinc supplementation.

**Authors&#039; conclusions:** 
There is no convincing evidence that zinc supplementation to infants or children results in improved motor or mental development.
AN  - CD007991
AU  - Gogia,
AU  - S.
AU  - Sachdev,
AU  - H.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007991.pub2
KW  - Dietary Supplements
KW  - Child Development [drug effects] [physiology]
KW  - Cognition [drug effects] [physiology]
KW  - Motor Skills [drug effects] [physiology]
KW  - Trace Elements [administration &amp; dosage]
KW  - Zinc [administration &amp; dosage]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Behav
PY  - 2012
T2  - Cochrane Database of Systematic Reviews
TI  - Zinc supplementation for mental and motor development in children
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007991.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007991.pub2/asset/CD007991.pdf?v=1&amp;t=iw7lfdct&amp;s=fa8eda7e83002bbcd119c354b49b955542d6d007
ER  -
TY  - JOUR
AB  - This meta-analysis examined the effect of behavioral parent training on child and parental outcomes for children with attention deficit hyperactivity disorder. 

Meta-analytic procedures were used to estimate the effect of behavioral parent training on children with attention deficit hyperactivity disorder. Variables moderating the intervention effect were examined. 

Forty studies were included and generated an overall moderate effect size at post-treatment and a small effect size at follow-up. The majority of outcome categories were associated with a moderate effect size at post-treatment that decreased to a small effect size at follow-up. 

Parenting competence was the only outcome that had a large effect, which decreased to moderate at follow-up. 

The strength of the effect differed between questionnaire and observation measures. Behavioral parent training is an effective intervention for children with attention deficit hyperactivity disorder. 

Sustainability of the effects over time is a problem that awaits further scrutiny. 

Recommendations for further research and clinical practices are provided.

Copyright &copy; 2012 Elsevier Ltd. All rights reserved.
AD  - Lee,Pei-chin. School of Occupational Therapy, Chung Shan Medical University No. 110, Sec. 1, Jiang-Gou N. Road, Taichung, Taiwan. peggy@csmuedu.tw
AN  - 22750360
AU  - Lee,
AU  - P.
AU  - C.
AU  - Niew,
AU  - W.
AU  - I.
AU  - Yang,
AU  - H.
AU  - J.
AU  - Chen,
AU  - V.
AU  - C.
AU  - Lin,
AU  - K.
AU  - C.
DA  - Nov-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.ridd.2012.05.011.
DP  - Ovid Technologies
J2  - Res Dev Disabil
KW  - Adolescent Attention Deficit Disorder with Hyperactivity/di [Diagnosis] Attention Deficit Disorder with Hyperactivity/px [Psychology] *Attention Deficit Disorder with Hyperactivity/th [Therapy] *Behavior Therapy/ed [Education] Behavior Therapy/mt [Metho
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Lee, Pei-chin Niew, Wern-ing Yang, Hao-jan Chen, Vincent Chin-hung Lin, Keh-chung
PY  - 2012
SP  - 2040-9
T2  - Research in Developmental Disabilities
TI  - A meta-analysis of behavioral parent training for children with attention deficit hyperactivity disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=22750360
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22750360&amp;id=doi:10.1016%2Fj.ridd.2012.05.011&amp;issn=0891-4222&amp;isbn=&amp;volume=33&amp;issue=6&amp;spage=2040&amp;pages=2040-9&amp;date=2012&amp;title=Research+in+Developmental+Disabilities&amp;atitle=A+meta-analysis+of+behavioral+parent+training+for+children+with+attention+deficit+hyperactivity+disorder.&amp;aulast=Lee&amp;pid=%3Cauthor%3ELee+PC%3C%2Fauthor%3E%3CAN%3E22750360%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0891422212001278/1-s2.0-S0891422212001278-main.pdf?_tid=cf303b7e-167b-11e5-9395-00000aacb362&amp;acdnat=1434715851_38ed9635ad66dfb2fe5cc107cf567036
VL  - 33
ER  -
TY  - JOUR
AB  - **Objective: **
The use of second-generation antipsychotics (SGAs) in youth has increased considerably. Increases are mainly attributable to treatment of disruptive behaviour disorders (DBDs). Our objective was to review the evidence regarding the efficacy of SGAs for DBDs in youth. 

**Method: **
We performed a systematic review of all randomized controlled trials (RCTs) of SGAs and placebo for the treatment of DBDs in youth, focusing on efficacy data. 

**Results: **
Eight RCTs in youth with DBDs were included. Five RCTs evaluated the use of risperidone in youth with the combination of subaverage borderline IQ and disruptive behaviour aggression. Single RCTs evaluated the use of risperidone for treatment-resistant aggression in attention-deficit hyperactivity disorder and for the treatment of conduct disorder (CD), and a single ROT evaluated the use of quetiapine for adolescent CD. The efficacy results of each of these studies are described. 

**Conclusion: **
Four placebo-controlled studies support the short-term efficacy of low-dose risperidone in youth with a subaverage IQ. Placebo-controlled evidence is weak or nonexistent for SGAs other than risperidone, and is weak in youth with an average IQ. Multiple factors likely account for the disconnect between this limited evidence base and the frequent use of SGAs for DBDs in clinical practice. These include extrapolation from studies in youth with autism or a subaverage IQ to normally developing youth; ease of SGA titration and the mistaken perception that little monitoring is required; unavailability of psychosocial treatments; limited familiarity with other pharmacological options; clinical and cultural norms; and the influence of the pharmaceutical industry.
AD  - [Pringsheim, Tamara] Univ Calgary, Dept Clin Neurosci Psychiat &amp; Pediat, Calgary, AB, Canada. [Gorman, Daniel] Univ Toronto, Dept Psychiat, Toronto, ON, Canada. Pringsheim, T (reprint author), Alberta Childrens Prov Gen Hosp, 2888 Shaganappi Trail NW, Calgary, AB T3B 6A8, Canada. tmprings@ucalgary.ca
AN  - WOS:000312514000003
AU  - Pringsheim,
AU  - T.
AU  - Gorman,
AU  - D.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/070674371205701203
J2  - Can. J. Psychiat.-Rev. Can. Psychiat.
KW  - second-generation antipsychotics disruptive behaviour disorders attention-deficit hyperactivity disorder conduct disorder oppositional defiant disorder children ATTENTION-DEFICIT/HYPERACTIVITY DISORDER DOUBLE-BLIND AGGRESSIVE-BEHAVIOR CONDUCT DISORDER A
L1  - internal-pdf://2322934508/Pringsheim-2012-Second-Generation Antipsychoti.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 056TJ Times Cited: 7 Cited Reference Count: 30 Pringsheim, Tamara Gorman, Daniel Shire Canada Dr Pringsheim has received consultation and speaking fees from Shire Canada. Dr Gorman has nothing to disclose. 8 CANADIAN PSYCHIATRIC ASSOC OTTAWA CAN J PSYCHIAT
PY  - 2012
SP  - 722-727
T2  - Canadian Journal of Psychiatry-Revue Canadienne De Psychiatrie
TI  - Second-Generation Antipsychotics for the Treatment of Disruptive Behaviour Disorders in Children: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000312514000003http://media.proquest.com/media/pq/classic/doc/2865682511/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Pringsheim%2C+Tamara%2C+MD%2C+MSc%3BGorman%2C+Daniel%2C+MD&amp;cit%3Atitle=Second-Generation+Antipsychotics+for+the+Treatment+of+Disruptive+...&amp;cit%3Apub=Canadian+Journal+of+Psychiatry&amp;cit%3Avol=57&amp;cit%3Aiss=12&amp;cit%3Apg=722&amp;cit%3Adate=Dec+2012&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMjA4Mjk0MjEwNTo4Nzg1OTUSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFMzU1NDcyCjEyNjk0OTU5NzA6DURvY3VtZW50SW1hZ2VCATBSBk9ubGluZVoCRlRiA1BGVGoKMjAxMi8xMi8wMXIKMjAxMi8xMi8zMXoAggEpUC0xMDAwMjczLTMxMDc1LUNVU1RPTUVSLTEwMDAwMTU3LTExMTUxMTKSAQZPbmxpbmXKAQdFbmROb3Rl0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCKE9TOkVNUy1QZGZEb2NWaWV3QmFzZS1nZXRNZWRpYVVybEZvckl0ZW3KAg9BcnRpY2xlfEZlYXR1cmXSAgFZ4gIBTvICAA%3D%3D&amp;_s=QxOtpcvWtV6ZPngXY72ShsRxNBg%3D
UR  - http://journals.sagepub.com/doi/pdf/10.1177/070674371205701203
VL  - 57
ER  -
TY  - JOUR
AB  - **Background:** 
Attention Deficit Hyperactivity Disorder (ADHD) is a common childhood psychiatric disorder with features of inattention, hyperactivity and impulsivity. There is increasing interest in complementary and alternative therapies such as acupuncture; however, it remains unclear whether the use of acupuncture in children and adolescents with ADHD is supported by the existing evidence.

**Objectives:** 
To assess the efficacy and safety of acupuncture as a treatment for ADHD in children and adolescents.

**Search methods:** 
We searched CENTRAL (The Cochrane Library 2010, Issue 2); MEDLINE (21 May 2010); CINAHL (21 May 2010); EMBASE (21 May 2010); ERIC (21 May 2010); PsycINFO (21 May 2010), Chinese Biological Medicine Database (10 May 2010); Chinese Scientific Periodical Database of VIP INFORMATION (10 May 2010); China Periodical in China National Knowledge Infrastructure (10 May 2010); and Chinese Evidence-Based Medicine Database (10 May 2010). We handsearched Chinese language journals and conference proceedings.

**Selection criteria:** 
Randomised controlled trials and quasi-randomised controlled trials comparing acupuncture with placebo or sham acupuncture, or conventional treatment. Participants under the age of 18 years with any type of ADHD were included. Papers in any language were included.

**Data collection and analysis:** 
Two review authors (S Li, B Yu) independently determined the studies to be included in the review based on inclusion and exclusion criteria and extracted the data using pre-developed extraction forms. The risk of bias within the trials was assessed by the same review authors in relation to allocation concealment, blinding and withdrawals. The measures of ADHD outcomes were extracted from core symptoms rating scales and additional secondary outcomes were considered.

**Main results:** 
No studies met the inclusion criteria for this review.

**Authors&#039; conclusions:** 
A comprehensive search showed that there is no evidence base of randomised or quasi-randomised controlled trials to support the use of acupuncture as a treatment for ADHD in children and adolescents. Due to the lack of trials, we cannot reach any conclusions about the efficacy and safety of acupuncture for ADHD in children and adolescents. This review highlights the need for further research in this area in the form of high quality, large scale, randomised controlled trials.&nbsp;
AN  - CD007839
AU  - Li,
AU  - S.
AU  - Yu,
AU  - B.
AU  - Zhou,
AU  - D.
AU  - He,
AU  - C.
AU  - Kang,
AU  - L.
AU  - Wang,
AU  - X.
AU  - Jiang,
AU  - S.
AU  - Chen,
AU  - X.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD007839.pub2
KW  - Acupuncture Therapy Attention Deficit Disorder with Hyperactivity [therapy] Adolescent[checkword] Child[checkword] Humans[checkword] Behav
L1  - internal-pdf://0588190888/Shasha-2011-Acupuncture for Attention Deficit.pdf
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Acupuncture for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007839.pub2/abstract
UR  - http://onlinelibrary.wiley.com/store/10.1002/14651858.CD007839.pub2/asset/CD007839.pdf?v=1&amp;t=ib7uo926&amp;s=0a8d9fc8d9fe0c3be62e0d79813c35503b38642b
ER  -
TY  - JOUR
AB  - Clinical trials exploring the use of counseling and psychotherapy to treat alcohol and other drug use problems in school-aged youth were meta-analyzed using a random effects model. 

Of 374 possible studies identified, 20 studies were accepted into the analysis comprising 28 samples of participants (n = 2,837). Counseling and psychotherapy interventions for school-aged youth were inconsistently effective in lowering alcohol use at termination and not effective at follow-up. 

Effects of counseling and psychotherapy for drug abuse were consistently significant at termination, but follow-up effects yielded inconsistent results. 

With the exception of a sample size effect in the single group drug abuse treatment follow-up analysis, all tests of homogeneity (Cochran&#039;s Q and I2) indicated no substantial effects of moderating variables. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Erford, Bradley T.: berford@loyola.edu Erford, Bradley T.: Loyola University Maryland, Timonium Graduate Center, 2034 Greenspring Drive, Timonium, MD, US, 21093, berford@loyola.edu Rongione, Danielle: School Counseling Program, Loyola University Maryland, Timonium, MD, US Erford, Bradley T.: School Counseling Program, Education Specialties Department, School of Education, Loyola University Maryland, Timonium, MD, US Broglie, Caren: School Counseling Program, Loyola University Maryland, Timonium, MD, US
AN  - 2014-20716-002
AU  - Rongione,
AU  - D.
AU  - Erford,
AU  - B.
AU  - T.
AU  - Broglie,
AU  - C.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/2150137811400595
DP  - Ovid Technologies
KW  - alcohol addiction, drug abuse, counseling outcomes, school-aged youth, psychotherapy, alcohol rehabilitation *Alcohol Rehabilitation *Alcoholism *Counseling *Drug Abuse *Psychotherapy Substance Abuse &amp; Addiction [3233] Drug &amp; Alcohol Rehabilitation [338
LA  - English
M3  - Meta Analysis
PY  - 2011
SP  - 8-24
T2  - Counseling Outcome Research and Evaluation
TI  - Alcohol and other drug abuse counseling outcomes for school-aged youth: A meta-analysis of studies from 1990 to 2009
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2014-20716-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F2150137811400595&amp;issn=2150-1378&amp;isbn=&amp;volume=2&amp;issue=1&amp;spage=8&amp;pages=8-24&amp;date=2011&amp;title=Counseling+Outcome+Research+and+Evaluation&amp;atitle=Alcohol+and+other+drug+abuse+counseling+outcomes+for+school-aged+youth%3A+A+meta-analysis+of+studies+from+1990+to+2009.&amp;aulast=Rongione&amp;pid=%3Cauthor%3ERongione%2C+Danielle%3C%2Fauthor%3E%3CAN%3E2014-20716-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://cor.sagepub.com/content/2/1/8http://cor.sagepub.com/content/2/1/8.full.pdf
VL  - 2
ER  -
TY  - JOUR
AB  - **Background:** 
Exogenous melatonin helps in regulating the circadian rhythm and is widely used for the management of sleep disorders in visually impaired children.&nbsp;

**Objectives:** 
The aim of the review was to assess melatonin therapy for treatment of non-respiratory sleep disorders in visually impaired children, with regard to improvement in sleep habit, sleep scheduling and sleep maintenance, when compared with placebo or no treatment.

**Search methods:** 
We searched the following databases between February 2011 and July 2011: the Cochrane Central Register of Controlled Trials (CENTRAL) 2011(1) searched on 4th February 2011; MEDLINE (1950 to June Week 3, 2011) searched on 20th June 2011; EMBASE (1980 to June Week 4, 2011) searched on 7th July 2011; CINAHL (1937 to 21 September 2011); the metaRegister of Controlled Trials (this includes ClinicalTrial.gov) searched 20 July 2011, and reference lists of papers identified after initial screening.&nbsp;

**Selection criteria:** 
We planned to include randomized controlled trials (RCTs) and quasi-RCTs, including cross-over studies.&nbsp;Treatment would be exogenous melatonin.&nbsp;Control groups could be placebo, other medication for sleep disorders or no treatment. Outcomes sought were improved sleep with regard to timing and duration, quality of life and adverse events.&nbsp;

**Data collection and analysis:** 
Three review authors independently assessed trials for inclusion in the review.

**Main results:** 
We did not find any studies fulfilling the inclusion criteria, therefore no outcome data are reported.We identified nine studies after initial screening and, after further evaluation, we excluded these. The excluded studies involved a total of 163 individuals aged two years to 18 years.&nbsp;We excluded studies for three main reasons: they were non-randomized or case series studies, they were studies of people over 18 years of age or even where the study was randomised, the study population was mixed and results pertaining to the visually impaired cohort could not be independently evaluated. No significant adverse effects of melatonin were reported in these excluded studies.

**Authors&#039; conclusions:**
There is currently no high quality data to support or refute the use of melatonin&nbsp;for sleep disorders in visually impaired children.&nbsp;Placebo-controlled trials examining important clinical outcomes such as sleep quality, sleep latency, duration of sleep and night-time awakenings are needed. As the numbers of children meeting study inclusion criteria are likely to be low at individual sites, multicentre collaboration between developmental paediatricians, sleep physicians and other health care professionals is essential to achieve sufficient sample size for controlled studies.&nbsp;Such collaboration would help facilitate local recruitment at multiple sites, with study oversight being provided by paediatricians with expertise in sleep disorders. Participation of collaborators with experience in evidence-based practice research is also desirable due to the lack of protocols on melatonin therapy in the target population.
AN  - CD008473
AU  - Khan,
AU  - S.
AU  - Heussler,
AU  - H.
AU  - McGuire,
AU  - T.
AU  - Dakin,
AU  - C.
AU  - Pache,
AU  - D.
AU  - Cooper,
AU  - D.
AU  - Norris,
AU  - R.
AU  - Flenady,
AU  - V.
AU  - Charles,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd008473
KW  - Disabled Children
KW  - Visually Impaired Persons
KW  - Central Nervous System Depressants [therapeutic use]
KW  - Melatonin [therapeutic use]
KW  - Sleep Disorders, Circadian Rhythm [drug therapy]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Melatonin for non-respiratory sleep disorders in visually impaired children
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008473.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD008473.pub2/asset/CD008473.pdf?v=1&amp;t=iw7k46uo&amp;s=6974b478b2bb72eec55162643cbd3e58dbb50342
ER  -
TY  - JOUR
AB  - Clinical trials exploring the effectiveness of counseling and psychotherapy in treatment of depression in school-age youth composed this meta-analysis. 

Results were synthesized using a random effects model for mean difference and mean gain effect size estimates. No effects of moderating variables were evident. 

Counseling and psychotherapy are effective for treatment of depression in school-age youth both at termination and follow-up, and in school and nonschool settings.
AD  - [Erford, Bradley T.] Loyola Univ Maryland, Sch Educ, Educ Specialties Dept, Timonium Grad Ctr, Lutherville Timonium, MD 21093 USA. [Erford, Breann M.] Drexel Univ, Dept Psychol, Philadelphia, PA USA. Erford, BT (reprint author), Loyola Univ Maryland, Sch Educ, Educ Specialties Dept, Timonium Grad Ctr, 2034 Greenspring Dr, Lutherville Timonium, MD 21093 USA. berford@loyola.edu
AN  - WOS:000301571900007
AU  - Erford,
AU  - B.
AU  - T.
AU  - Erford,
AU  - B.
AU  - M.
AU  - Lattanzi,
AU  - G.
AU  - Weller,
AU  - J.
AU  - Schein,
AU  - H.
AU  - Wolf,
AU  - E.
AU  - Hughes,
AU  - M.
AU  - Darrow,
AU  - J.
AU  - Savin-Murphy,
AU  - J.
AU  - Peacock,
AU  - E.
DA  - Fal
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/j.1556-6676.2011.tb02841.x
J2  - J. Couns. Dev.
KW  - COGNITIVE-BEHAVIORAL TREATMENT RANDOMIZED CONTROLLED-TRIAL SEROTONIN REUPTAKE INHIBITORS PUERTO-RICAN ADOLESCENTS INTERPERSONAL PSYCHOTHERAPY CHILDHOOD DEPRESSION GROUP-THERAPY INTERVENTION PROGRAMS SUPPORTIVE THERAPY MAJOR DEPRESSION Psychology, Applie
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 909NR Times Cited: 7 Cited Reference Count: 112 Erford, Bradley T. Erford, Breann M. Lattanzi, Gina Weller, Janet Schein, Hallie Wolf, Emily Hughes, Meredith Darrow, Jenna Savin-Murphy, Janet Peacock, Elizabeth 7 WILEY PERIODICALS, INC MALDEN J COUNS DEV
PY  - 2011
SP  - 439-457
T2  - Journal of Counseling and Development
TI  - Counseling Outcomes From 1990 to 2008 for School-Age Youth With Depression: A Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000301571900007http://onlinelibrary.wiley.com/store/10.1002/j.1556-6676.2011.tb02841.x/asset/j.1556-6676.2011.tb02841.x.pdf?v=1&amp;t=ib3i0r57&amp;s=ca66aa64cb826ad4499b7f08fb9431a86d2d4e93
VL  - 89
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Treatment of sleep disorders in visually impaired children is complicated by a complex pathophysiology, a high incidence of sleep disorders in this population, and a dearth of management options. The significant impact on the health of these children and distress to their caregivers warrant a systematic assessment of the published literature on therapeutic approaches. 

**OBJECTIVE: **
This systematic review aims to assess the current therapeutic options in the management of sleep disorders in visually impaired children to identify knowledge gaps and guide future research. 

**METHODS: **
A search of primary literature was conducted using the bibliographic databases PubMed (1980-August 2010), EMBASE (1990-August 2010), Science Citation Index Expanded (1990-August 2010), and CINHAL (1992-August 2010) and the Cochrane Central Register of Controlled Trials (CENTRAL). Additional studies were identified through snowballing search techniques (manually by searching retrieved references and electronically by using citation-tracking software). Search terms included behavioral treatment, children, circadian rhythm, hypnosedatives, intellectual disability, light therapy, melatonin, phototherapy, random allocation, randomized controlled trial (RCT), sleep disorder, and visual impairment. Randomized and quasi-randomized clinical trials of therapeutic options (behavioral treatment, light therapy, melatonin, or hypnosedatives) used in participants aged 3 months to 18 years who had both a visual impairment and a sleep disorder were included. Independent extraction of articles was performed by 2 authors using predefined data fields, including quality of the therapeutic options, based on the Strength of Recommendation Taxonomy evidence-rating system. 

**RESULTS: **
Two RCTs were retrieved for melatonin, with improved effect on sleep latency (P = 0.019 and P &lt; 0.05, respectively). However, separate analysis for visual impairment was not conducted. No RCTs were retrieved for behavioral intervention, light therapy, or hypnosedatives. Three studies using behavioral therapy (2 case reports and 1 case series) anecdotally showed improvement in sleep habit. No improvement in sleep rhythm was observed with a case series applying light therapy as an intervention. 

**CONCLUSIONS: **
Children with visual impairment and sleep disorders are a heterogeneous patient group, making diagnosis and treatment difficult. RCTs on treatment options remain in their infancy, with a lack of evidence for appropriate therapeutic strategies. Trials across a range of selected diagnoses need to be conducted with adequate sample populations to differentiate the efficacy of 4 different treatment modalities (behavioral therapy, light therapy, melatonin, and hypnosedatives) as agents for improving sleep.

Copyright &copy; 2011 Elsevier HS Journals, Inc. All rights reserved.
AD  - Khan,Sohil A. School of Pharmacy, University of Queensland, Brisbane, Queensland, Australia. sohailkhan1981@gmail.com
AN  - 21497703
AU  - Khan,
AU  - S.
AU  - A.
AU  - Heussler,
AU  - H.
AU  - McGuire,
AU  - T.
AU  - Dakin,
AU  - C.
AU  - Pache,
AU  - D.
AU  - Norris,
AU  - R.
AU  - Cooper,
AU  - D.
AU  - Charles,
AU  - B.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.clinthera.2011.03.002
DP  - Ovid Technologies
J2  - Clin Ther
KW  - Behavior Therapy Central Nervous System Depressants/ad [Administration &amp; Dosage] Central Nervous System Depressants/tu [Therapeutic Use] Child Circadian Rhythm Humans Hypnotics and Sedatives/ad [Administration &amp; Dosage] Hypnotics and Sedatives/tu [Thera
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Khan, Sohil A Heussler, Helen McGuire, Treasure Dakin, Carolyn Pache, David Norris, Ross Cooper, David Charles, Bruce
PY  - 2011
SP  - 168-81
T2  - Clinical Therapeutics
TI  - Therapeutic options in the management of sleep disorders in visually impaired children: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21497703 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21497703&amp;id=doi:10.1016%2Fj.clinthera.2011.03.002&amp;issn=0149-2918&amp;isbn=&amp;volume=33&amp;issue=2&amp;spage=168&amp;pages=168-81&amp;date=2011&amp;title=Clinical+Therapeutics&amp;atitle=Therapeutic+options+in+the+management+of+sleep+disorders+in+visually+impaired+children%3A+a+systematic+review.&amp;aulast=Khan&amp;pid=%3Cauthor%3EKhan+SA%3C%2Fauthor%3E%3CAN%3E21497703%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0149291811001421/1-s2.0-S0149291811001421-main.pdf?_tid=b846e44a-1972-11e5-a602-00000aab0f6c&amp;acdnat=1435041801_fab48d06d6da3d4fa90e59a20d86e899
VL  - 33
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Many young people with major depression fail first-line treatments. Treatment-resistant depression has various definitions in the literature but typically assumes nonresponse to medication. In young people, cognitive behavioral therapy (CBT) is the recommended first-line intervention, thus the definition of treatment resistance should be expanded. Therefore, our aim was to synthesize the existing evidence of any interventions for treatment-resistant depression, broadly defined, in children and adolescents and to investigate the effectiveness of CBT in this context. 

**METHODS: **
We used Cochrane Collaboration methodology, with electronic searches of Medline, PsycINFO, Embase, and the Cochrane Depression Anxiety and Neurosis Group trials registers. Only randomized controlled trials were included, and were assessed for risk of bias. Meta- analysis was undertaken where possible and appropriate. 

**RESULTS:** 
Of 953 articles retrieved, four trials were eligible for inclusion. For one study, only the trial registration document was available, because the study was never completed. All other studies were well conducted with a low risk of bias, although one study had a high dropout rate. Two studies assessed the effect of adding CBT to medication. While an assertive trial of antidepressants does appear to lead to benefit, when compared with placebo, there was no significant advantage, in either study, or in a meta-analysis of data from these trials, that clearly demonstrated an additional benefit of CBT. The third trial showed little advantage of a tricyclic antidepressant over placebo in the context of an inpatient admission. 

**CONCLUSION: **
Few randomized controlled trials have investigated interventions for treatment-resistant depression in young people, and results from these show modest benefit from antidepressants with no additional benefit over medication from CBT. Overall, there is a lack of evidence about effective interventions to treat young people who have failed to respond to evidence-based interventions for depression. Research in this area is urgently required.
AD  - Hetrick,Sarah E. Orygen Youth Health Research Centre, Centre for Youth Mental Health, Melbourne, Parkville, Victoria, Australia.
AN  - 22114540
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Cox,
AU  - G.
AU  - R.
AU  - Merry,
AU  - S.
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.2147/prbm.s13780
DP  - Ovid Technologies
J2  - Psychol
LA  - English
N1  - Hetrick, Sarah E Cox, Georgina R Merry, Sally N
PY  - 2011
SP  - 97-112
T2  - Psychology Research &amp; Behavior Management
TI  - Treatment-resistant depression in adolescents: is the addition of cognitive behavioral therapy of benefit?
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=22114540
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:22114540&amp;id=doi:10.2147%2FPRBM.S13780&amp;issn=1179-1578&amp;isbn=&amp;volume=4&amp;issue=&amp;spage=97&amp;pages=97-112&amp;date=2011&amp;title=Psychology+Research+%26+Behavior+Management&amp;atitle=Treatment-resistant+depression+in+adolescents%3A+is+the+addition+of+cognitive+behavioral+therapy+of+benefit%3F.&amp;aulast=Hetrick&amp;pid=%3Cauthor%3EHetrick+SE%3C%2Fauthor%3E%3CAN%3E22114540%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.dovepress.com/getfile.php?fileID=10669
VL  - 4
ER  -
TY  - JOUR
AB  - Social interaction is a fundamental problem for children with autism spectrum disorders (ASD). Various types of social skills interventions have been developed and used by clinicians to promote the social interaction in children with ASD. 

This meta-analysis used hierarchical linear modeling (HLM) to examine the effectiveness of peer-mediated and video-modeling approaches, the two approaches that are most commonly used for social skills training of children with ASD. 

The two approaches, with the average effect size of 1.27 (peer-mediated approach: mean = 1.3, 95% CL = 1.10-1.50, N = 9; video-modeling approach: mean = 1.22, 95% CL = 0.65-1.78, N = 5) were found to significantly and equally improve the social performance of children with ASD. 

In addition, age functioned as a significant moderator in the effectiveness of the intervention. Implications of the results and limitations of this study are discussed. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Wang, Shin-Yi: shinwangw@yahoo.com.tw Wang, Shin-Yi: University of Alberta, Educational Psychology, 6-102 Education North, Edmonton, AB, Canada, T6G 2G5, shinwangw@yahoo.com.tw Wang, Shin-Yi: University of Alberta, Edmonton, AB, Canada Cui, Ying: University of Alberta, Edmonton, AB, Canada Parrila, Rauno: University of Alberta, Edmonton, AB, Canada
AN  - 2010-22960-061
AU  - Wang,
AU  - S-Y.
AU  - Cui,
AU  - Y.
AU  - Parrila,
AU  - R.
DA  - Jan-Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.rasd.2010.06.023
DP  - Ovid Technologies
KW  - peers, video modeling, social skills training, children, autism spectrum disorders *Autism *Peers *Pervasive Developmental Disorders *Social Skills Training *Videotapes Developmental Disorders &amp; Autism [3250] Health &amp; Mental Health Treatment &amp; Preventio
LA  - English
M3  - Meta Analysis
PY  - 2011
SP  - 562-569
T2  - Research in Autism Spectrum Disorders
TI  - Examining the effectiveness of peer-mediated and video-modeling social skills interventions for children with autism spectrum disorders: A meta-analysis in single-case research using HLM
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2010-22960-061 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.rasd.2010.06.023&amp;issn=1750-9467&amp;isbn=&amp;volume=5&amp;issue=1&amp;spage=562&amp;pages=562-569&amp;date=2011&amp;title=Research+in+Autism+Spectrum+Disorders&amp;atitle=Examining+the+effectiveness+of+peer-mediated+and+video-modeling+social+skills+interventions+for+children+with+autism+spectrum+disorders%3A+A+meta-analysis+in+single-case+research+using+HLM.&amp;aulast=Wang&amp;pid=%3Cauthor%3EWang%2C+Shin-Yi%3C%2Fauthor%3E%3CAN%3E2010-22960-061%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1750946710001108/1-s2.0-S1750946710001108-main.pdf?_tid=af6795bc-167b-11e5-8a90-00000aab0f01&amp;acdnat=1434715798_ea8984a4a59c1436af5a725da102708a
VL  - 5
ER  -
TY  - JOUR
AB  - **Background: **
Single traumatising events are associated with an elevated rate of psychological disorders in children and adolescents. To date, it remains unclear whether early psychological interventions can reduce longer term psychological maladjustment. 

**Objective: **
To systematically review the literature to determine the characteristics and efficacy of early psychological interventions in children and adolescents after a single, potentially-traumatising event. 

**Design: **
Systematic searches were conducted of all relevant bibliographic databases. Studies on early psychological interventions were included if the first session was conducted within 1 month of the event. Two independent observers assessed each study for eligibility, using pre-determined inclusion and exclusion criteria, and rated the study&#039;s methodological quality. A meta-analysis was conducted on the group effects between individuals allocated to intervention versus control groups. Hence, effect sizes (ES) and confidence intervals were computed as well as heterogeneity and analogue-to-the ANOVA analyses. 

**Results: **
Seven studies (including four randomised controlled trials) met the inclusion criteria. Depending on the specific outcome variable (e.g., dissociation, anxiety and arousal), small to large beneficial ES were noted. Although the meta-analysis revealed unexplained heterogeneity between the ES of the included studies, and although studies varied greatly with regards to their methodological quality and the interventions tested, findings suggest that early interventions should involve psycho-education, provide individual coping-skills and probably involve some kind of trauma exposure. Also, a stepped procedure that includes an initial risk screen and the provision of multiple sessions to those children at risk may be a promising strategy. 

**Conclusions: **
To date, research on the effectiveness of early interventions in children after a potentially traumatising event remains scarce. However, our review suggests that early interventions may be helpful. 

(PsycINFO Database Record (c) 2017 APA, all rights reserved)
AD  - Kramer, Didier N.: Department of Psychosomatics, University Children&#039;s Hospital Zurich, Zurich, Switzerland Landolt, Markus A.: Department of Psychosomatics, University Children&#039;s Hospital Zurich, Zurich, Switzerland
AN  - 2014-26491-001
AU  - Kramer,
AU  - D.
AU  - N.
AU  - Landolt,
AU  - M.
AU  - A.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
KW  - systematic review, PTSD, post-traumatic stress, crisis intervention, critical incident stress debriefing
KW  - *Age Differences
KW  - *Crisis Intervention
KW  - *Posttraumatic Stress Disorder
KW  - *Self-Efficacy
KW  - Neuroses &amp; Anxiety Disorders [3215]
KW  - Community &amp; Social Services [3373]
KW  - Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
L1  - internal-pdf://1749953890/EJPT-2-7858.pdf
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2011
T2  - European Journal of Psychotraumatology
TI  - Characteristics and efficacy of early psychological interventions in children and adolescents after single trauma: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc13&amp;AN=2014-26491-001http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=2000-8066&amp;isbn=&amp;volume=2&amp;issue=&amp;spage=7858&amp;pages=&amp;date=2011&amp;title=European+Journal+of+Psychotraumatology&amp;atitle=Characteristics+and+efficacy+of+early+psychological+interventions+in+children+and+adolescents+after+single+trauma%3A+A+meta-analysis.&amp;aulast=Kramer&amp;pid=%3Cauthor%3EKramer%2C+Didier+N%3C%2Fauthor%3E%3CAN%3E2014-26491-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 2
ER  -
TY  - JOUR
AB  - The aim of this study was to determine the effectiveness of a social marketing approach in reduction of unintended teenage pregnancies. 

We identified studies undertaken between 1990 and 2008 through electronic searches of databases, manual searches of bibliographies, and consultations with experts. Twelve studies that met the inclusion criteria were selected for further analysis. 

Results showed variation in intervention effects across specified outcomes (reduction in unintended pregnancies, delayed sexual initiation, contraceptive use at last intercourse, knowledge of contraception and reproductive health, and self-efficacy to refuse unwanted sex). Of the 12 studies, 9 reported significant effects on at least one of the outcomes. Long-term interventions were generally more effective than short-term ones for most outcomes. The impact on male participants&#039; sexual behavior was minimal in most studies. 

Overall, social marketing appears to be an effective approach in reducing teenage pregnancies and influencing sexual behavior change, but the evidence is limited to particular outcomes and context. There is, therefore, need for more primary studies specifically designed around social marketing principles for more robust evaluations. The minimal impact on male participants&#039; behavior also warrants further investigation. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Wakhisi, Anthony Simiyu: Centre for Public Health Research, Brunel University, Uxbridge, United Kingdom Allotey, Pascale: Jeffrey Cheah School of Medicine &amp; Health Sciences, Monash University, Malaysia Dhillon, Namrata: Centre for Public Health Research, Brunel University, Uxbridge, United Kingdom Reidpath, Daniel D.: Jeffrey Cheah School of Medicine &amp; Health Sciences, Monash University, Malaysia
AN  - 2011-05054-004
AU  - Wakhisi,
AU  - A.
AU  - S.
AU  - Allotey,
AU  - P.
AU  - Dhillon,
AU  - N.
AU  - Reidpath,
AU  - D.
AU  - D.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15245004.2010.546941
DP  - Ovid Technologies
KW  - social marketing, teenage pregnancy, developed countries, self efficacy *Adolescent Pregnancy *Self Efficacy *Social Marketing Developed Countries Psychosocial &amp; Personality Development [2840] Promotion &amp; Maintenance of Health &amp; Wellness [3365] Human Ad
LA  - English
M3  - Literature Review
PY  - 2011
SP  - 56-90
T2  - Social Marketing Quarterly
TI  - The effectiveness of social marketing in reduction of teenage pregnancies: A review of studies in developed countries
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2011-05054-004 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F15245004.2010.546941&amp;issn=1524-5004&amp;isbn=&amp;volume=17&amp;issue=1&amp;spage=56&amp;pages=56-90&amp;date=2011&amp;title=Social+Marketing+Quarterly&amp;atitle=The+effectiveness+of+social+marketing+in+reduction+of+teenage+pregnancies%3A+A+review+of+studies+in+developed+countries.&amp;aulast=Wakhisi&amp;pid=%3Cauthor%3EWakhisi%2C+Anthony+Simiyu%3C%2Fauthor%3E%3CAN%3E2011-05054-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://smq.sagepub.com/content/17/1/56http://smq.sagepub.com/content/17/1/56.full.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - Second-generation antipsychotics (SGA) are being used more often than ever before in children and adolescents with psychotic and a wide range of non-psychotic disorders. Several SGA have received regulatory approval for some paediatric indications in various countries, but off-label use is still frequent. 

The aim of this paper was to perform a systematic review and critically evaluate the literature on cardiometabolic and endocrine side-effects of SGA in children and adolescents through a Medline/Pubmed/Google Scholar search of randomized, placebo controlled trials of antipsychotics in children and adolescents (&lt;18 years old) until February 2010. 

In total, 31 randomized, controlled studies including 3595 paediatric patients were identified. A review of these data confirmed that SGA are associated with relevant cardiometabolic and endocrine side-effects, and that children and adolescents have a high liability to experience antipsychotic induced hyperprolactinaemia, weight gain and associated metabolic disturbances. 

Only weight change data were sufficiently reported to conduct a formal meta-analysis. In 24 trials of 3048 paediatric patients with varying ages and diagnoses, ziprasidone was associated with the lowest weight gain (-0.04 kg, 95% confidence interval [CI]: -0.38 to +0.30), followed by aripiprazole (0.79 kg, 95% CI: 0.54 to 1.04], quetiapine (1.43 kg, 95% CI: 1.17 to 1.69) and risperidone (1.76 kg, 95% CI: 1.27 to 2.25) were intermediate, and olanzapine was associated with weight gain the most (3.45 kg, 95% CI: 2.93 to 3.97). 

Significant weight gain appeared to be more prevalent in patients with autistic disorder who were also younger and likely less exposed to antipsychotics previously. These data clearly suggest that close screening and monitoring of metabolic side effects is warranted and that the least cardiometabolically problematic agents should be used first whenever possible. 

A good collaboration between child- and adolescent psychiatrists, general practitioners and paediatricians is essential to maximize overall outcomes and to reduce the likelihood of premature cardiovascular morbidity and mortality. 

(C) 2010 Elsevier Masson SAS. All rights reserved.
AD  - [De Hert, M.] Ctr Catholic Univ Leuven, B-3070 Kortenberg, Belgium. [Dobbelaere, M.] Univ Leuven, Psychiat Ctr Catholic, Gasthuisberg, Belgium. [Sheridan, E. M.; Correll, C. U.] Zucker Hillside Hosp, Glen Oaks, NY USA. [Cohen, D.] Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, NL-9700 AB Groningen, Netherlands. [Cohen, D.] GGZ NHN, Div Chron Care, Heerhugowaard, Netherlands. [Correll, C. U.] Albert Einstein Coll Med, Bronx, NY 10467 USA. De Hert, M (reprint author), Ctr Catholic Univ Leuven, Campus Kortenberg,Leuvensesteenweg 517, B-3070 Kortenberg, Belgium. marc.de.hert@uc-kortenberg.be
AN  - WOS:000289705200004
AU  - De
AU  - Hert,
AU  - M.
AU  - Dobbelaere,
AU  - M.
AU  - Sheridan,
AU  - E.
AU  - M.
AU  - Cohen,
AU  - D.
AU  - Correll,
AU  - C.
AU  - U.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.eurpsy.2010.09.011
J2  - Eur. Psychiat.
KW  - Adolescents Antipsychotics Cardiovascular disease Children Diabetes Guidelines Management Monitoring Side-effects Weight gain DISRUPTIVE BEHAVIOR DISORDERS INDUCED WEIGHT-GAIN BIPOLAR-I DISORDER ATTENTION-DEFICIT/HYPERACTIVITY DISORDER PERVASIVE DEVELOP
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 752PR Times Cited: 69 Cited Reference Count: 130 De Hert, M. Dobbelaere, M. Sheridan, E. M. Cohen, D. Correll, C. U. Correll, Christoph/D-3530-2011 69 ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER PARIS EUR PSYCHIAT
PY  - 2011
SP  - 144-158
T2  - European Psychiatry
TI  - Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: A systematic review of randomized, placebo controlled trials and guidelines for clinical practice
UR  - &lt;Go to ISI&gt;://WOS:000289705200004http://ac.els-cdn.com/S0924933810001999/1-s2.0-S0924933810001999-main.pdf?_tid=e0e50752-18db-11e5-8991-00000aab0f6b&amp;acdnat=1434977015_05aae36ffeb1d2f265d7580f47570be6
VL  - 26
ER  -
TY  - JOUR
AB  - **Objective: **
The purpose of this study was to review empirical evidence of the effects of placement in group care compared to other interventions.

**Method:**
Two-group empirical studies were identified and effect sizes for all reported outcomes were calculated. 

**Results: **
Nineteen two-group studies were found that compared group care with family foster care, treatment foster care, no placement, and different group care models. Most effects were small to moderate, with strongest effects for shorter lengths of stay for family-centered group care models and decreased delinquency for Multidimensional Treatment Foster Care (MTFC) compared to group care. 

**Conclusion: **
Based on the limited number of two-group studies of varying quality, outcomes of group care are often worse than alternative interventions. However, some group care models seem more promising than others. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Lee, Bethany R.: blee@ssw.umaryland.edu Lee, Bethany R.: School of Social Work, University of Maryland, Baltimore, 525 W. Redwood St., Baltimore, MD, US, 21201, blee@ssw.umaryland.edu Lee, Bethany R.: School of Social Work, University of Maryland, Baltimore, MD, US Bright, Charlotte L.: School of Social Work, University of Maryland, Baltimore, MD, US Svoboda, Deborah V.: School of Social Work, University of Maryland, Baltimore, MD, US Fakunmoju, Sunday: Westfield State University, Department of Social Work, Westfield, MA, US Barth, Richard P.: School of Social Work, University of Maryland, Baltimore, MD, US
AN  - 2011-03038-003
AU  - Lee,
AU  - B.
AU  - R.
AU  - Bright,
AU  - C.
AU  - L.
AU  - Svoboda,
AU  - D.
AU  - V.
AU  - Fakunmoju,
AU  - S.
AU  - Barth,
AU  - R.
AU  - P.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1049731510386243
DP  - Ovid Technologies
KW  - group care outcomes, youth, intervention, treatment effectiveness comparisons, foster care *Foster Care *Group Homes *Intervention *Treatment Effectiveness Evaluation Health &amp; Mental Health Treatment &amp; Prevention [3300] Human
LA  - English
M3  - Literature Review
PY  - 2011
SP  - 177-189
T2  - Research on Social Work Practice
TI  - Outcomes of group care for youth: A review of comparative studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2011-03038-003 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1049731510386243&amp;issn=1049-7315&amp;isbn=&amp;volume=21&amp;issue=2&amp;spage=177&amp;pages=177-189&amp;date=2011&amp;title=Research+on+Social+Work+Practice&amp;atitle=Outcomes+of+group+care+for+youth%3A+A+review+of+comparative+studies.&amp;aulast=Lee&amp;pid=%3Cauthor%3ELee%2C+Bethany+R%3C%2Fauthor%3E%3CAN%3E2011-03038-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rsw.sagepub.com/content/21/2/177http://rsw.sagepub.com/content/21/2/177.full.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - This is a review and meta-analysis of school-based intervention programs targeted at reducing symptoms of posttraumatic stress disorder (PTSD). 

Nineteen studies conducted in 9 different countries satisfied the inclusionary criteria. 

The studies dealt with various kinds of type I and type II trauma exposure. 

Sixteen studies used cognitive-behavioral therapy methods; the others used play/art, eye movement desensitization and reprocessing, and mind-body techniques. 

The overall effect size for the 19 studies was d = 0.68 (SD = 0.41), indicating a medium-large effect in relation to reducing symptoms of PTSD. 

The authors&#039; findings suggest that intervention provided within the school setting can be effective in helping children and adolescents following traumatic events.

Copyright &copy; 2011 International Society for Traumatic Stress Studies.
AD  - Rolfsnes,Erika S. Centre for Behavioural Research,University of Stavanger, Stavanger, Norway. esrolfsnes@yahoo.com
AN  - 21425191
AU  - Rolfsnes.
AU  - E.
AU  - S.
AU  - Idsoe,
AU  - T.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/jts.20622
DP  - Ovid Technologies
J2  - J Trauma Stress
KW  - Adolescent Child Female Humans Male *School Health Services *Stress Disorders, Post-Traumatic/pp [Physiopathology] *Stress Disorders, Post-Traumatic/th [Therapy]
L1  - internal-pdf://0427063916/Rolfsnes-2011-School-based intervention progra.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Rolfsnes, Erika S Idsoe, Thormod Comment in: J Trauma Stress. 2011 Dec;24(6):760-1; discussion 762; PMID: 22131060
PY  - 2011
SP  - 155-65
T2  - Journal of Traumatic Stress
TI  - School-based intervention programs for PTSD symptoms: a review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21425191
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21425191&amp;id=doi:10.1002%2Fjts.20622&amp;issn=0894-9867&amp;isbn=&amp;volume=24&amp;issue=2&amp;spage=155&amp;pages=155-65&amp;date=2011&amp;title=Journal+of+Traumatic+Stress&amp;atitle=School-based+intervention+programs+for+PTSD+symptoms%3A+a+review+and+meta-analysis.&amp;aulast=Rolfsnes&amp;pid=%3Cauthor%3ERolfsnes+ES%3C%2Fauthor%3E%3CAN%3E21425191%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1002/jts.20622/asset/20622_ftp.pdf?v=1&amp;t=ib3jvigl&amp;s=5424dd2cb720251bc5c9290f7e925b9ad02d062f
UR  - http://onlinelibrary.wiley.com/store/10.1002/jts.20622/asset/20622_ftp.pdf?v=1&amp;t=j8yftyhw&amp;s=a76e98aa079f7b7a118ac8d0e7b45a777da5d595
VL  - 24
ER  -
TY  - JOUR
AB  - **PURPOSE: **
The effectiveness of pharmacologic therapy for smoking cessation in adolescent smokers was evaluated. 

**METHODS: **
In this meta-analysis, the medical literature was searched for randomized controlled trials (RCTs) investigating the effect of pharmacologic therapy for smoking cessation in smokers age 20 years or younger. The overall effect of pharmacologic therapy was based on the longest follow-up data available in each study. The effects of pharmacologic therapy by follow-up period, type of pharmacologic therapy, and type of strategy analysis were also compared among RCTs. Secondary outcome measures were adverse events reported from each study. 

**RESULTS: **
Six RCTs involving 816 smokers age 12-20 years were included in the final analysis. No significant increase in abstinence rates was detected with pharmacologic therapy (relative risk [RR], 1.38; 95% confidence interval [CI], 0.92-2.07; I(2) = 0.0%) in a fixed-effects meta-analysis. Similarly, no significant increase in abstinence rates was found in subgroup meta-analyses of studies with both short-term (&lt;= 12 weeks) (RR, 1.23; 95% CI, 0.92-1.65) and mid-term (26 weeks) follow-up periods (RR, 1.60; 95% CI, 0.90-2.82). Although few serious adverse events were reported, there was no evidence directly linking these effects to the pharmacologic therapy used. 

**CONCLUSION: **
A meta-analysis found that pharmacologic therapy for smoking cessation among adolescent smokers did not have a significant 
effect on abstinence rates at short-term and mid-term follow-up times of &lt;26 weeks, and the RCTs examined found few adverse events. However, the results may have been affected by the limited number of participants in published trials.
AN  - 21258027
AU  - Kim,
AU  - Y.
AU  - Myung,
AU  - S.
AU  - K.
AU  - Jeon,
AU  - Y.
AU  - J.
AU  - Lee,
AU  - E.
AU  - H.
AU  - Park,
AU  - C.
AU  - H.
AU  - Seo,
AU  - H.
AU  - G.
AU  - Huh,
AU  - B.
AU  - Y.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.2146/ajhp100296
L1  - internal-pdf://0933764111/Kim-2011-Effectiveness of pharmacologic therap.pdf
PY  - 2011
SP  - 219-26
T2  - American Journal of Health-System Pharmacy
TI  - Effectiveness of pharmacologic therapy for smoking cessation in adolescent smokers: Meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=21258027
VL  - 68
ER  -
TY  - JOUR
AB  - The use of medications to manage problem behaviours is widespread. 

However, robust evidence to support their use seems to be lacking. 

The aim was to review research evidence into the efficacy of atypical antipsychotic medication in managing problem behaviour in children with intellectual disabilities and borderline intelligence. 

A systematic review was conducted for placebo-controlled randomised double-blind trials. 

The included studies (N = 6) showed that risperidone was significantly more effective than placebo in managing problem behaviours. 

However, most studies highlighted adverse events primarily somnolence and weight gain. 

There is now some evidence in favour of the use of risperidone. However, because of possible adverse events, these medications have to be used with caution.

Copyright &copy; 2011 Elsevier Ltd. All rights reserved.
AD  - Unwin,Gemma L. University of Birmingham, School of Psychology, Birmingham, UK. G.L.Unwin@bham.ac.uk
AN  - 21856116
AU  - Unwin,
AU  - G.
AU  - L.
AU  - Deb,
AU  - S.
DA  - Nov-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ridd.2011.07.031
DP  - Ovid Technologies
J2  - Res Dev Disabil
KW  - *Antipsychotic Agents/tu [Therapeutic Use] Child *Child Behavior Disorders/co [Complications] *Child Behavior Disorders/dt [Drug Therapy] Humans *Intellectual Disability/co [Complications] 0 (Antipsychotic Agents)
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Unwin, Gemma L Deb, Shoumitro
PY  - 2011
SP  - 2121-33
T2  - Research in Developmental Disabilities
TI  - Efficacy of atypical antipsychotic medication in the management of behaviour problems in children with intellectual disabilities and borderline intelligence: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21856116
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21856116&amp;id=doi:10.1016%2Fj.ridd.2011.07.031&amp;issn=0891-4222&amp;isbn=&amp;volume=32&amp;issue=6&amp;spage=2121&amp;pages=2121-33&amp;date=2011&amp;title=Research+in+Developmental+Disabilities&amp;atitle=Efficacy+of+atypical+antipsychotic+medication+in+the+management+of+behaviour+problems+in+children+with+intellectual+disabilities+and+borderline+intelligence%3A+a+systematic+review.&amp;aulast=Unwin&amp;pid=%3Cauthor%3EUnwin+GL%3C%2Fauthor%3E%3CAN%3E21856116%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0891422211002885/1-s2.0-S0891422211002885-main.pdf?_tid=e483b85c-167b-11e5-97ee-00000aacb35d&amp;acdnat=1434715887_ddaf48537908b3b664b9f72c7b56eba4
VL  - 32
ER  -
TY  - JOUR
AB  - **Background: **
Comorbidity is common among child clinical samples. Reviews on effective intervention for comorbid problems are lacking. 

**Method: **
Based on a literature search of three databases (PsycINFO, MEDLINE and ERIC), initial data analysis was carried out on 865 studies; of these, 10 randomised trials fully met study inclusion criteria and were subject to final analysis, with quality assessments and effect sizes calculated. 

**Results: **
Overall, effect sizes for externalising (M = 1.12) and internalising (M = 1.09) outcomes were large. Effect sizes were large for family-based (M = 1.80) compared to individual (M = 0.78) and group-based (M = 0.54) interventions. Studies with homotypic comorbidity (M = 1.18) displayed larger treatment effect sizes than ones with heterotypic comorbidity (M = 0.54). 

**Conclusions: **
While the overall quality ratings of the reviewed studies varied from mediocre to good, with a variety of measures used across studies to assess the same outcomes, findings suggest that current interventions are effective for reducing internalising and externalising problems in children with comorbidity. More substantive evidence for the beneficial effects of psychosocial interventions for children with comorbid problems may arise as more robust studies, which more explicitly address and describe comorbidity, become available.
AD  - [Riosa, Priscilla Burnham; McArthur, Brae Anne; Preyde, Michele] Univ Guelph, Guelph, ON N1G 2W1, Canada. Riosa, PB (reprint author), Univ Guelph, Guelph, ON N1G 2W1, Canada. mpreyde@uoguelph.ca
AN  - WOS:000296251600001
AU  - Riosa,
AU  - P.
AU  - B.
AU  - McArthur,
AU  - B.
AU  - A.
AU  - Preyde,
AU  - M.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1475-3588.2011.00609.x
J2  - Child Adolesc. Ment. Health
KW  - Systematic review effectiveness psychosocial intervention comorbid ATTENTION DEFICIT/HYPERACTIVITY DISORDER RANDOMIZED CONTROLLED-TRIAL ANXIETY DISORDERS PSYCHIATRIC-DISORDERS DISRUPTIVE BEHAVIOR CONDUCT PROBLEMS SUBSTANCE USE THERAPY DEPRESSION PREVALE
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 837YW Times Cited: 5 Cited Reference Count: 46 Riosa, Priscilla Burnham McArthur, Brae Anne Preyde, Michele 5 WILEY-BLACKWELL HOBOKEN CHILD ADOL MENT H-UK
PY  - 2011
SP  - 177-185
T2  - Child and Adolescent Mental Health
TI  - Effectiveness of psychosocial intervention for children and adolescents with comorbid problems: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000296251600001http://onlinelibrary.wiley.com/store/10.1111/j.1475-3588.2011.00609.x/asset/j.1475-3588.2011.00609.x.pdf?v=1&amp;t=ib7ni00p&amp;s=5ae733e5eeb0a8c9c0290d1f8041b9f234f1b458
VL  - 16
ER  -
TY  - JOUR
AB  - **Background:** 
Oxcarbazepine, a keto derivative of the ?mood stabiliser? carbamazepine, may have efficacy in the treatment of acute episodes of bipolar disorder. Potentially, it may offer pharmacokinetic advantages over carbamazepine.

**Objectives:** 
To review the efficacy and acceptability of oxcarbazepine compared to placebo and other agents in the treatment of acute bipolar episodes including mania, mixed episodes and depression.

**Search methods:** 
Electronic databases were searched up to 2 September 2011. Specialist journals and conference proceedings were handsearched. Authors, experts in the field and pharmaceutical companies were contacted requesting information on published and unpublished trials.

**Selection criteria:** 
Randomised controlled trials (RCTs) which compared oxcarbazepine with placebo or alternative agents, where the stated intent of intervention was the acute treatment of bipolar affective disorder were sought. Participants with bipolar disorder of either sex and of all ages were included.

**Data collection and analysis:** 
Data were extracted from the original reports individually by two review authors. For dichotomous data, odds ratios (ORs) were calculated with 95% confidence intervals (CI). Continuous data were analysed using standardised mean differences (with 95% CI).

**Main results:** 
Seven studies were included in the analysis (368 participants in total). All were on mania, hypomania, mixed episodes or rapid-cycling disorder. Overall, their methodological quality was relatively low.There was no difference in the primary outcome analysis ? a fall of &nbsp;50% or more on the Young Mania Rating Scale (YMRS) - between oxcarbazepine and placebo (N=1, n=110, OR =2.10, 95% CI 0.94 to 4.73) in one study, conducted in children; no studies were available in adult participants.In comparison with other mood stabilisers, there was no difference between oxcarbazepine and valproate as an antimanic agent using the primary outcome (50% or more fall in YMRS, OR=0.44, 95% CI 0.10 to 1.97, 1 study, n=60, P=0.273) or the secondary outcome measure (differences in YMRS between the two groups, SMD=0.18, 95% CI -0.24 to 0.59, 2 studies, n=90, P=0.40). No primary or secondary efficacy outcome measures were found comparing oxcarbazepine with lithium monotherapy.As an adjunctive treatment to lithium, oxcarbazepine reduced depression rating scale scores more than carbamazepine in a group of manic participants on the Montgomery-Åsberg Depression Rating Scale (MADRS) (SMD=- 1.12, 95% CI -1.71 to -0.53, 1 study, n=52, P=0.0002) and on the Hamilton Depression Rating Scale (HDRS) (SMD=- 0.77, 95% CI -1.35 to -0.20, 1 study, n=52, P=0.008).There was a higher incidence of adverse effects, particularly neuropsychiatric, in participants randomised to oxcarbazepine compared to those on placebo (1 study, n=115, 17% to 39% of participants on oxcarbazepine had at least one such event compared to 7% to 10% on placebo).There was no difference in adverse events rates between oxcarbazepine and other mood stabilisers or haloperidol.

**Authors&#039; conclusions:** 
Currently, there are insufficient trials of adequate methodological quality on oxcarbazepine in the acute treatment of bipolar disorder to inform us on its efficacy and acceptability. Studies predominantly examine the treatment of mania: there are data from subgroup analysis on mixed affective, hypomania and rapid-cycling states.From the few studies included in this review, oxcarbazepine did not differ in efficacy compared to placebo in children and adolescents. It did not differ from other active agents in adults. It may have a poorer tolerability profile compared to placebo. No data were found on outcomes relevant to patients and clinicians, such as length of hospital admission. &nbsp;There is a need for adequately powered randomised controlled trials of good methodological quality to inform us of the therapeutic potential of oxcarbazepine across the spectrum of acute episodes in bipolar disorder.
AN  - CD004857
AU  - Vasudev,
AU  - A.
AU  - Macritchie,
AU  - K.
AU  - Vasudev,
AU  - K.
AU  - Watson,
AU  - S.
AU  - Geddes,
AU  - J.
AU  - Young,
AU  - A.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004857.pub2
KW  - Acute Disease
KW  - Antimanic Agents [therapeutic use]
KW  - Bipolar Disorder [drug therapy] [psychology]
KW  - Carbamazepine [analogs &amp; derivatives] [therapeutic use]
KW  - Lithium Compounds [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Valproic Acid [therapeutic use]
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Oxcarbazepine for acute affective episodes in bipolar disorder
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004857.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004857.pub2/asset/CD004857.pdf?v=1&amp;t=iw7kgec9&amp;s=452a23118980cbad66c3c6d47993c3d1bc1e1830
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
Web-based treatments can deliver broad reaching, relatively inexpensive, and clinically tested methods for smoking cessation. We performed a systematic review of randomized controlled trials (RCTs) of smoking cessation to evaluate the efficacy of Web-based interventions in adults, college students, and adolescents. 

**METHODS:** 
MEDLINE, EMBASE, The Cochrane Library, CINAHL, and PsycINFO were searched from January 1, 1990 through February 12, 2010 for RCTs examining the efficacy of Web-based smoking cessation programs. Paired reviewers abstracted data on study design, patient characteristics, and outcomes sequentially and did quality assessments independently. 

**RESULTS: **
Twenty-one RCTs met eligibility criteria, with 15 conducted among adults. Among adults, 2 RCTs found that a multicomponent intervention with Web and non-Web-based elements was more efficacious than a self-help manual, and one of 2 RCTs found that Web-based interventions may be more effective than no treatment. Three trials provided insufficient evidence to demonstrate whether Web-based interventions were more efficacious than counseling. By contrast, tailored Web sites in 2 RCTs and greater Web site exposure in 6 of 7 RCTs were associated with higher rates of abstinence. Among college students, evidence supporting use of Web-based interventions was insufficient because the one RCT conducted was also a multicomponent intervention. Five RCTs among adolescents demonstrated mixed results, with insufficient evidence supporting their efficacy. 

**CONCLUSIONS: **
Evidence supporting the use of Web-based interventions for smoking cessation is insufficient to moderate in adults and insufficient in college students and adolescents. These RCTs have, however, elucidated clinical, methodological, and statistical practices that are likely to improve future trial design and treatment delivery.
AD  - Hutton,Heidi E. Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N. Wolfe St., Baltimore, MD 21287, USA. hhutton@jhmi.edu
AN  - 21350042
AU  - Hutton,
AU  - H.
AU  - E.
AU  - Wilson,
AU  - L.
AU  - M.
AU  - Apelberg,
AU  - B.
AU  - J.
AU  - Tang,
AU  - E.
AU  - A.
AU  - Odelola,
AU  - O.
AU  - Bass,
AU  - E.
AU  - B.
AU  - Chander,
AU  - G.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1093/ntr/ntq252
DP  - Ovid Technologies
J2  - Nicotine Tob Res
KW  - Adolescent Adult Humans Internet Outcome Assessment (Health Care)/sn [Statistics &amp; Numerical Data] Patient Acceptance of Health Care/sn [Statistics &amp; Numerical Data] Randomized Controlled Trials as Topic Self Care/mt [Methods] Self Care/ut [Utilization]
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Hutton, Heidi E Wilson, Lisa M Apelberg, Benjamin J Tang, Erika Avila Odelola, Olaide Bass, Eric B Chander, Geetanjali
PY  - 2011
SP  - 227-38
T2  - Nicotine and Tobacco Research
TI  - A systematic review of randomized controlled trials: Web-based interventions for smoking cessation among adolescents, college students, and adults
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21350042 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21350042&amp;id=doi:10.1093%2Fntr%2Fntq252&amp;issn=1462-2203&amp;isbn=&amp;volume=13&amp;issue=4&amp;spage=227&amp;pages=227-38&amp;date=2011&amp;title=Nicotine+%26+Tobacco+Research&amp;atitle=A+systematic+review+of+randomized+controlled+trials%3A+Web-based+interventions+for+smoking+cessation+among+adolescents%2C+college+students%2C+and+adults.&amp;aulast=Hutton&amp;pid=%3Cauthor%3EHutton+HE%3C%2Fauthor%3E%3CAN%3E21350042%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ntr.oxfordjournals.org/content/13/4/227http://ntr.oxfordjournals.org/content/13/4/227.longhttp://ntr.oxfordjournals.org/content/13/4/227.full.pdf
UR  - https://academic.oup.com/ntr/article-abstract/13/4/227/1023920/A-Systematic-Review-of-Randomized-Controlled?redirectedFrom=fulltext
VL  - 13
ER  -
TY  - JOUR
AB  - The authors conducted a review of the literature with regard to child and adolescent mental health intervention, from which they identified 20 unique publications and 12 separate interventions. These interventions encompassed depression, anxiety, substance abuse, eating disorders, and mental health promotion. Studies were heterogeneous, with a wide range of study designs and comparison groups creating some challenges in interpretation. However, modest evidence was found that Internet interventions showed benefits compared with controls and preintervention symptom levels. Interventions had been developed for a range of settings, but tended to recruit middle-class participants of European ethnicity. Internet interventions showed a range of approaches toward engaging children and incorporating parents and peers into the learning process. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Van Voorhees, Benjamin W.: bvanvoor@medicine.bsd.uchicago.edu Van Voorhees, Benjamin W.: Section of General Internal Medicine, Department of Medicine, University of Chicago, 5841 South Maryland Boulevard, Chicago, IL, US, 60637, bvanvoor@medicine.bsd.uchicago.edu Siemer, Christopher P.: Section of General Internal Medicine, Department of Medicine, University of Chicago, Chicago, IL, US Fogel, Joshua: Department of Finance and Business Management, Brooklyn College of the, City University of New York, Brooklyn, NY, US Van Voorhees, Benjamin W.: Section of General Internal Medicine, Department of Medicine, University of Chicago, Chicago, IL, US
AN  - 2010-24269-016
AU  - Siemer,
AU  - C.
AU  - P.
AU  - Fogel,
AU  - J.
AU  - Van
AU  - Voorhees,
AU  - B.
AU  - W.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.chc.2010.08.012
DP  - Ovid Technologies
KW  - telemedicine, mental health services, web based applications, children, adolescents *Internet *Mental Health Services *Telemedicine *Computer Assisted Therapy Health &amp; Mental Health Services [3370] Communication Systems [2700] Human Childhood (birth-12
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2011
SP  - 135-153
T2  - Child and Adolescent Psychiatric Clinics of North America
TI  - Telemental health and web-based applications in children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2010-24269-016 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.chc.2010.08.012&amp;issn=1056-4993&amp;isbn=&amp;volume=20&amp;issue=1&amp;spage=135&amp;pages=135-153&amp;date=2011&amp;title=Child+and+Adolescent+Psychiatric+Clinics+of+North+America&amp;atitle=Telemental+health+and+web-based+applications+in+children+and+adolescents.&amp;aulast=Siemer&amp;pid=%3Cauthor%3ESiemer%2C+Christopher+P%3C%2Fauthor%3E%3CAN%3E2010-24269-016%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1056499310000763/1-s2.0-S1056499310000763-main.pdf?_tid=689d2dc2-18ba-11e5-90cc-00000aacb360&amp;acdnat=1434962640_e80d04661858fc11ba5c1035b620f994
VL  - 20
ER  -
TY  - JOUR
AB  - In children and adolescents the Second Generation Antipsychotics (SGAs) represent the class of psychotropic drugs whose use has grown more significantly in recent years: they are primarily used for treatment of patients with disruptive behavior disorders, mood disorders and pervasive developmental disorders or mental retardation. 
In order to compare the efficacy and tolerability of antipsychotics against placebo or each other, a systematic Medline/PubMed search for randomized, double blind studies on SGA in patients younger than 18 years of age at enrollment, was conducted. Papers on schizophrenia, discussed in another article of this specific issue, were excluded by the efficacy analysis. 

A set of standard efficacy and safety indices, such as treatment effect sizes (ES), the Numbers Needed to Treat (NNT) and Numbers Needed to Harm (NNH), was used to compare medications. 32 studies analyzing efficacy and/or tolerability of SGAs in children and adolescents with bipolar, autistic or disruptive behavior disorders, and Tourette syndrome were identified. SGAs efficacy on mania, extreme mood variability, irritability, aggression and disruptive behavior appears to be greater than for psychotic symptoms in schizophrenia: average NNT was 2-5, whereas for schizophrenia it varies between 3 for risperidone and 10 for olanzapine, quetiapine, and aripiprazole. As for schizophrenia, different SGAs show a similar efficacy for specific non-psychotic disorders, but they significantly differ in their safety profile. 

In randomized studies, adverse effects were usually relatively minor, easily predictable and manageable, whereas long-term open-label studies have indicated that some adverse event, such as the metabolic effects, may be severe and potentially life threatening on the long-term. 

Taken together, these findings suggest that the choice of a specific treatment should be guided primarily by the safety profile of specific antipsychotics, considering specific risk factors (i.e. obesity and BMI, family history of diabetes or cardiovascular disorder, etc) for the single patient.

Copyright &copy; 2011 Elsevier B.V. All rights reserved.
AD  - Zuddas,Alessandro. Centre for Pharmacological Therapy in Child &amp; Adolescent Neuropsychiatry, Department of Neuroscience &quot;B.B. Brodie&quot;, University of Cagliari, Italy. azuddas@unica.it
AN  - 21550212
AU  - Zuddas,
AU  - A.
AU  - Zanni,
AU  - R.
AU  - Usala,
AU  - T.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.euroneuro.2011.04.001
DP  - Ovid Technologies
J2  - Eur Neuropsychopharmacol
KW  - Adolescent Antipsychotic Agents/ae [Adverse Effects] Antipsychotic Agents/tu [Therapeutic Use] *Antipsychotic Agents *Bipolar Disorder/dt [Drug Therapy] Child *Developmental Disabilities/dt [Drug Therapy] Double-Blind Method Female Humans Male *Psychoti
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Zuddas, Alessandro Zanni, Roberta Usala, Tatiana
PY  - 2011
SP  - 600-20
T2  - European Neuropsychopharmacology
TI  - Second generation antipsychotics (SGAs) for non-psychotic disorders in children and adolescents: a review of the randomized controlled studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21550212 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21550212&amp;id=doi:10.1016%2Fj.euroneuro.2011.04.001&amp;issn=0924-977X&amp;isbn=&amp;volume=21&amp;issue=8&amp;spage=600&amp;pages=600-20&amp;date=2011&amp;title=European+Neuropsychopharmacology&amp;atitle=Second+generation+antipsychotics+%28SGAs%29+for+non-psychotic+disorders+in+children+and+adolescents%3A+a+review+of+the+randomized+controlled+studies.&amp;aulast=Zuddas&amp;pid=%3Cauthor%3EZuddas+A%3C%2Fauthor%3E%3CAN%3E21550212%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0924977X11000708/1-s2.0-S0924977X11000708-main.pdf?_tid=f695c4ba-18db-11e5-9150-00000aab0f27&amp;acdnat=1434977051_7c9009d6e8379aa64d688c3aa2e6c48a
VL  - 21
ER  -
TY  - JOUR
AB  - **Objective **
To synthesise reviews investigating physical activity and depression, anxiety, self-esteem and cognitive functioning in children and adolescents and to assess the association between sedentary behaviour and mental health by performing a brief review. 

**Methods **
Searches were performed in 2010. Inclusion criteria specified review articles reporting chronic physical activity and at least one mental health outcome that included depression, anxiety/stress, self-esteem and cognitive functioning in children or adolescents. 

**Results** 
Four review articles reported evidence concerning depression, four for anxiety, three for self-esteem and seven for cognitive functioning. Nine primary studies assessed associations between sedentary behaviour and mental health. Physical activity has potentially beneficial effects for reduced depression, but the evidence base is limited. Intervention designs are low in quality, and many reviews include cross-sectional studies. Physical activity interventions have been shown to have a small beneficial effect for reduced anxiety, but the evidence base is limited. Physical activity can lead to improvements in self-esteem, at least in the short term. However, there is a paucity of good quality research. Reviews on physical activity and cognitive functioning have provided evidence that routine physical activity can be associated with improved cognitive performance and academic achievement, but these associations are usually small and inconsistent. Primary studies showed consistent negative associations between mental health and sedentary behaviour. 

**Conclusions **
Association between physical activity and mental health in young people is evident, but research designs are often weak and effects are small to moderate. Evidence shows small but consistent associations between sedentary screen time and poorer mental health.
AD  - [Biddle, Stuart J. H.; Asare, Mavis] Univ Loughborough, Sch Sport Exercise &amp; Hlth Sci, Loughborough LE11 3TU, Leics, England. Biddle, SJH (reprint author), Univ Loughborough, Sch Sport Exercise &amp; Hlth Sci, Loughborough LE11 3TU, Leics, England. s.j.h.biddle@lboro.ac.uk
AN  - WOS:000293787200009
AU  - Biddle,
AU  - S.
AU  - J.
AU  - H.
AU  - Asare,
AU  - M.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1136/bjsports-2011-090185
J2  - Br. J. Sports Med.
KW  - SEDENTARY BEHAVIOR ACADEMIC-PERFORMANCE MEDIA USE METAANALYSIS EXERCISE DEPRESSION COGNITION ILLNESS YOUTH Sport Sciences
L1  - internal-pdf://0252013278/Biddle-2011-Physical activity and mental healt.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 806DV Times Cited: 112 Cited Reference Count: 44 Biddle, Stuart J. H. Asare, Mavis 115 B M J PUBLISHING GROUP LONDON BRIT J SPORT MED
PY  - 2011
SP  - 886-895
T2  - British Journal of Sports Medicine
TI  - Physical activity and mental health in children and adolescents: a review of reviews
UR  - &lt;Go to ISI&gt;://WOS:000293787200009http://bjsm.bmj.com/content/45/11/886.full.pdf
UR  - http://bjsm.bmj.com/content/bjsports/45/11/886.full.pdf
VL  - 45
ER  -
TY  - JOUR
AB  - **BACKGROUND AND OBJECTIVES: **
There is no clear gold standard treatment for childhood posttraumatic stress disorder (PTSD). An annotated bibliography and meta-analysis were used to examine the efficacy of cognitive behavioral therapy (CBT) in the treatment of pediatric PTSD as measured by outcome data from the Child Behavior Checklist (CBCL). 

**METHOD: **
A literature search produced 21 studies; of these, 10 utilized the CBCL but only eight were both 1) randomized; and 2) reported pre- and post-intervention scores. 

**RESULTS: **
The annotated bibliography revealed efficacy in general of CBT for pediatric PTSD. Using four indices of the CBCL, the meta-analysis identified statistically significant effect sizes for three of the four scales: Total Problems (TP; -.327; p = .003), Internalizing (INT; -.314; p = .001), and Externalizing (EXT; -.192; p = .040). The results for TP and INT were reliable as indicated by the fail-safe N and rank correlation tests. The effect size for the Total Competence (TCOMP; -.054; p = .620) index did not reach statistical significance. 

**LIMITATIONS: **
Limitations included methodological inconsistencies across studies and lack of a randomized control group design, yielding few studies for meta-analysis. 

**CONCLUSIONS: **
The efficacy of CBT in the treatment of pediatric PTSD was supported by the annotated bibliography and meta-analysis, contributing to best practices data. CBT addressed internalizing signs and symptoms (as measured by the CBCL) such as anxiety and depression more robustly than it did externalizing symptoms such as aggression and rule-breaking behavior, consistent with its purpose as a therapeutic intervention.

Copyright &copy; 2011 Elsevier Ltd. All rights reserved.
AD  - Kowalik,Joanna. University of Arizona College of Medicine Phoenix Campus, Maricopa Integrated Health System/District Medical Group, Desert Vista Behavioral Health Center, 570 West Brown Road, Mesa, AZ 85201, USA. Joanna_Kowalik@dmgaz.org
AN  - 21458405
AU  - Kowalik,
AU  - J.
AU  - Weller,
AU  - J.
AU  - Venter,
AU  - J.
AU  - Drachman,
AU  - D.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jbtep.2011.02.002
DP  - Ovid Technologies
J2  - J Behav Ther Exp Psychiatry
KW  - Adolescent Child Child, Preschool Clinical Trials as Topic/mt [Methods] *Cognitive Therapy/mt [Methods] Cognitive Therapy/sn [Statistics &amp; Numerical Data] Humans Psychiatric Status Rating Scales/sn [Statistics &amp; Numerical Data] Publication Bias/sn [Stat
LA  - English
M3  - Meta-Analysis Review
N1  - Kowalik, Joanna Weller, Jennifer Venter, Jacob Drachman, David
PY  - 2011
SP  - 405-13
T2  - Journal of Behavior Therapy &amp; Experimental Psychiatry
TI  - Cognitive behavioral therapy for the treatment of pediatric posttraumatic stress disorder: a review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21458405
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21458405&amp;id=doi:10.1016%2Fj.jbtep.2011.02.002&amp;issn=0005-7916&amp;isbn=&amp;volume=42&amp;issue=3&amp;spage=405&amp;pages=405-13&amp;date=2011&amp;title=Journal+of+Behavior+Therapy+%26+Experimental+Psychiatry&amp;atitle=Cognitive+behavioral+therapy+for+the+treatment+of+pediatric+posttraumatic+stress+disorder%3A+a+review+and+meta-analysis.&amp;aulast=Kowalik&amp;pid=%3Cauthor%3EKowalik+J%3C%2Fauthor%3E%3CAN%3E21458405%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0005791611000255/1-s2.0-S0005791611000255-main.pdf?_tid=6cc3f284-165b-11e5-ab5b-00000aacb361&amp;acdnat=1434701942_2b87dc9083378dc550087f6a2e8ed28b
VL  - 42
ER  -
TY  - JOUR
AB  - Suicide is a leading cause of death for young people and rates of serious suicidal thoughts are even higher. Due to these high rates and potential harm to youth, effective interventions are necessary. 

The purpose of this systematic review was to determine the impact of interventions designed for suicidal adolescents. Both quasi-experimental and experimental designs in the published and unpublished literature were included, and a total of 17 studies were located. According to meta-analysis, intervention group participants were slightly less likely to have suicidal and self-harm events than control group participants. 

However, when studies assessed outcome at a later period than immediately after intervention, experimental group participants were slightly more likely to have suicidal and self-harm events than control group participants. For studies that measured suicidal ideation at posttest, intervention group participants were slightly less likely to report suicidal ideation than control group participants, both at posttest and at follow-up. These contradictory findings are explored and discussed. 

(C) 2011 Elsevier Ltd. All rights reserved.
AD  - [Corcoran, Jacqueline; Dattalo, Patrick; Crowley, Meghan; Brown, Emily; Grindle, Lauren] Virginia Commonwealth Univ, Richmond, VA 23284 USA. Corcoran, J (reprint author), Virginia Commonwealth Univ, Richmond, VA 23284 USA. jcorcora@vcu.edu
AN  - WOS:000296365500006
AU  - Corcoran,
AU  - J.
AU  - Dattalo,
AU  - P.
AU  - Crowley,
AU  - M.
AU  - Brown,
AU  - E.
AU  - Grindle,
AU  - L.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2011.06.017
J2  - Child. Youth Serv. Rev.
KW  - Systematic review Meta-analysis Adolescent Suicide Intervention Suicidal behavior NOMINATED SUPPORT TEAM DELIBERATE SELF-HARM RANDOMIZED-TRIAL GROUP-THERAPY YOUTH PSYCHOTHERAPY METAANALYSIS BEHAVIOR CHILDREN Family Studies Social Work
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 839KV Times Cited: 2 Cited Reference Count: 31 Corcoran, Jacqueline Dattalo, Patrick Crowley, Meghan Brown, Emily Grindle, Lauren 2 PERGAMON-ELSEVIER SCIENCE LTD OXFORD CHILD YOUTH SERV REV
PY  - 2011
SP  - 2112-2118
T2  - Children and Youth Services Review
TI  - A systematic review of psychosocial interventions for suicidal adolescents
UR  - &lt;Go to ISI&gt;://WOS:000296365500006http://ac.els-cdn.com/S0190740911002313/1-s2.0-S0190740911002313-main.pdf?_tid=40e1b8da-18cd-11e5-929c-00000aacb360&amp;acdnat=1434970734_64ba2eaa2820f07d7c3c4c5ecc7eac1d
VL  - 33
ER  -
TY  - JOUR
AB  - **Background:** 
Social disadvantage can have a significant impact on early child development, health and wellbeing. What happens during this critical period is important for all aspects of development. Caregiving competence and the quality of the environment play an important role in supporting development in young children and parents have an important role to play in optimising child development and mitigating the negative effects of social disadvantage. Home-based child development programmes aim to optimise children&#039;s developmental outcomes through educating, training and supporting parents in their own home to provide a more nurturing and stimulating environment for their child.

**Objectives:**
To determine the effects of home-based programmes aimed specifically at improving developmental outcomes for preschool children from socially disadvantaged families.

**Search methods:** 
We searched the following databases between 7 October and 12 October 2010: Cochrane Central Register of Controlled Trials (CENTRAL) (2010, Issue 4), MEDLINE (1950 to week 4, September 2010), EMBASE (1980 to Week 39, 2010), CINAHL (1937 to current), PsycINFO (1887 to current), ERIC (1966 to current), ASSIA (1987 to current), Sociological Abstracts (1952 to current), Social Science Citation Index (1970 to current). We also searched reference lists of articles.

**Selection criteria:**
Randomised controlled trials comparing home-based preschool child development interventions with a &#039;standard care&#039; control. Participants were parents with children up to the age of school entry who were socially disadvantaged in respect of poverty, lone parenthood or ethnic minority status.

**Data collection and analysis:** 
Two authors independently selected studies, assessed the trials&#039; risk of bias and extracted data.

**Main results:** 
We included seven studies, which involved 723 participants. We assessed four of the seven studies as being at high risk of bias and three had an unclear risk of bias; the quality of the evidence was difficult to assess as there was often insufficient detail reported to enable any conclusions to be drawn about the methodological rigour of the studies. Four trials involving 285 participants measured cognitive development and we synthesised these data in a meta-analysis. Compared to the control group, there was no statistically significant impact of the intervention on cognitive development (standardised mean difference (SMD) 0.30; 95% confidence interval -0.18 to 0.78). Only three studies reported socioemotional outcomes and there was insufficient data to combine into a meta-analysis. No study reported on adverse effects.

**Authors&#039; conclusions:** 
This review does not provide evidence of the effectiveness of home-based interventions that are specifically targeted at improving developmental outcomes for preschool children from socially disadvantaged families. Future studies should endeavour to better document and report their methodological processes.
AN  - CD008131
AU  - Miller,
AU  - S.
AU  - Maguire,
AU  - L.
AU  - K.
AU  - Macdonald,
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd008131.pub2
KW  - Child Development
KW  - Social Environment
KW  - Child Welfare
KW  - Home Care Services [organization &amp; administration]
KW  - Parenting [psychology]
KW  - Randomized Controlled Trials as Topic
KW  - Vulnerable Populations [psychology]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Behav
L1  - internal-pdf://4026996145/Miller-2011-Home-based child development inter.pdf
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Home-based child development interventions for preschool children from socially disadvantaged families
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008131.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD008131.pub2/asset/CD008131.pdf?v=1&amp;t=iw7jnr29&amp;s=8db428900be29bde30ad3bc9a4e4b93c86e88e71
ER  -
TY  - JOUR
AB  - Aggressive behaviours often co-occur with other emotional, behavioural, academic, and social relationship problems. During adolescence, these children often exhibit increased rates of school dropout, depression, juvenile delinquency, substance abuse, and poor peer relationships. Some definitions focus on aggression as an emotion; according to this framework, aggressive behaviours stem from anger. 

Other definitions emphasise the motivational aspect of aggression, wherein intentions are thought to indicate the behavioural characteristics. Cognitive-behavioural therapy (CBT) is one of the most extensively researched forms of psychotherapy. This paper aims to review the literature on the use of CBT for treating children and adolescents who demonstrate high levels of violence. Studies were searched for using several methods. 

First, we used large database of literature on psychological treatments of violence in general. Studies were traced by means of several methods. A large database of 240 papers on the psychological treatment of aggression and violence in general were used. This database was developed through a comprehensive literature search (from 1997 to March 2009) in which we examined abstracts in ERIC (19 abstracts), Psycinfo (30), and Medline (23). 

Keywords used in computer searches were: Aggression, Violence, CBT, cognitive-behavioural therapy, cognitive therapy, behaviour therapy, and behavioural activation. The options were used in computer searches so that all relevant topics within the broader categories were searched as well. Six studies met the inclusion criteria, all of which indicated beneficial results of using CBT. A meta-analysis suggested an effect size of -0.094 for reduced violence as a result of CBT treatment; this is considered to be a medium effect. 

The differential effects of cognitive-behavioural therapy and affective education were variable, although they were also generally in the medium range. In this meta-analytic study, CBT treatment proved less effective in reducing aggressive behaviour. 

This review tentatively suggests potential for using CBT to reduce violence in children and adolescents. However, there is only a small body of research exploring this relationship at present. 

Further research is needed before any solid conclusions can be drawn. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - Ozabaci, Nilufer: niluferozabaci@hotmail.com Ozabaci, Nilufer: Eskisehir Osmangazi University Education Faculty Guidance and Counselling, Eskisehir, Turkey, 26480, niluferozabaci@hotmail.com Ozabaci, Nilufer: Eskisehir Osmangazi University Education, Faculty Guidance and Counselling, Eskisehir, Turkey
AN  - 2011-12809-001
AU  - Nilufer,
AU  - O.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2011.05.027
DP  - Ovid Technologies
KW  - cognitive behavioral therapy, violent behavior, age differences *Age Differences *Cognitive Behavior Therapy *Violence Cognitive Therapy [3311] Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
LA  - English
M3  - Meta Analysis
PY  - 2011
SP  - 1989-1993
T2  - Children and Youth Services Review
TI  - Cognitive behavioural therapy for violent behaviour in children and adolescents: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2011-12809-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2011.05.027&amp;issn=0190-7409&amp;isbn=&amp;volume=33&amp;issue=10&amp;spage=1989&amp;pages=1989-1993&amp;date=2011&amp;title=Children+and+Youth+Services+Review&amp;atitle=Cognitive+behavioural+therapy+for+violent+behaviour+in+children+and+adolescents%3A+A+meta-analysis.&amp;aulast=Ozabaci&amp;pid=%3Cauthor%3EOzabaci%2C+Nilufer%3C%2Fauthor%3E%3CAN%3E2011-12809-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0190740911002052/1-s2.0-S0190740911002052-main.pdf?_tid=24fd0c6e-18cd-11e5-8e45-00000aacb35d&amp;acdnat=1434970687_5804c3d002d7c4b3d7bae5bc2d26b024
VL  - 33
ER  -
TY  - JOUR
AB  - **Background **
Many adolescents receive mentoring. There is no systematic review if mentoring prevents alcohol and drug use. 

**Objectives **
Assess effectiveness of mentoring to prevent adolescent alcohol/drug use. 

**Search strategy **
Cochrane CENTRAL (issue 4), MEDLINE (1950-to July 2011), EMBASE (1980-to July 2011), 5 other electronic and 11 Grey literature electronic databases, 10 websites, reference lists, experts in addictions and mentoring. Selection criteria Randomised controlled trials (RCTs) of mentoring in adolescents to prevent alcohol/drug use. 

**Data collection and analysis **
We identified 2,113 abstracts, independently assessed 233 full-text articles, 4 RCTs met inclusion criteria. Two reviewers independently extracted data and assessed risks of bias. We contacted investigators for missing information.

**Main results **
We identified 4 RCTs (1,194 adolescents). No RCT reported enough detail to assess whether a strong randomisation method was used or allocation was concealed. Blinding was not possible as the intervention was mentoring. Three RCTs provided complete data. No selective reporting. Three RCTs provided evidence about mentoring and preventing alcohol use. We pooled two RCTs (RR for mentoring compared to no intervention = 0.71 (95% CI = 0.57 to 0.90, P value = 0.005). A third RCT found no significant differences. Three RCTs provided evidence about mentoring and preventing drug use, but could not be pooled. One found significantly less use of &quot;illegal&quot; drugs,&quot; one did not, and one assessed only marijuana use and found no significant differences. One RCT measured &quot;substance use&quot; without separating alcohol and drugs, and found no difference for mentoring. 

**Authors&#039; conclusions **
All four RCTs were in the US, and included &quot;deprived&quot; and mostly minority adolescents. Participants were young (in two studies age 12, and in two others 9-16). All students at baseline were non-users of alcohol and drugs. Two RCTs found mentoring reduced the rate of initiation of alcohol, and one of drug usage. The ability of the interventions to be effective was limited by the low rates of commencing alcohol and drug use during the intervention period in two studies (the use of marijuana in one study increased to 1% in the experimental and to 1.6% in the control group, and in another study drug usage rose to 6% in the experimental and 11% in the control group). However, in a third study there was scope for the intervention to have an effect as alcohol use rose to 19% in the experimental and 27% in the control group. The studies assessed structured programmes and not informal mentors.
AD  - [Thomas, Roger E.] Univ Calgary, Dept Med, UCMC, Calgary, AB T2M 1N7, Canada. [Lorenzetti, Diane] Univ Calgary, Ctr Hlth &amp; Policy Studies, Dept Community Hlth Sci, Fac Med, Calgary, AB T2M 1N7, Canada. Thomas, RE (reprint author), Univ Calgary, Dept Med, UCMC, 1707-1632 14th Ave, Calgary, AB T2M 1N7, Canada. rthomas@ucalgary.ca
AN  - WOS:000296871700040
AU  - Thomas,
AU  - R.
AU  - E.
AU  - Lorenzetti,
AU  - D.
AU  - Spragins,
AU  - W.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD007381.pub2
J2  - Cochrane Database Syst Rev.
KW  - RANDOMIZED CONTROLLED-TRIAL MULTIDIMENSIONAL FAMILY-THERAPY SCHOOL-BASED PREVENTION SUBSTANCE-ABUSE PREVENTION FOLLOW-UP EARLY-INTERVENTION RISK BEHAVIORS MIDDLE-SCHOOL MISUSE PREVENTION PROJECT NORTHLAND Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 846BH Times Cited: 1 Cited Reference Count: 158 Thomas, Roger E. Lorenzetti, Diane Spragins, Wendy 1 WILEY-BLACKWELL MALDEN COCHRANE DB SYST REV
PY  - 2011
SP  - 51
T2  - Cochrane Database of Systematic Reviews
TI  - Mentoring adolescents to prevent drug and alcohol use
UR  - &lt;Go to ISI&gt;://WOS:000296871700040http://onlinelibrary.wiley.com/store/10.1002/14651858.CD007381.pub2/asset/CD007381.pdf?v=1&amp;t=ib7uvjms&amp;s=417a4a4c674a92bd8ca2e7706d4787630f1977d8
ER  -
TY  - JOUR
AB  - **Objective** 
To assess the effectiveness of middle and high school-based suicide prevention curricula. 

**Data sources** 
The following were searched: Ovid MEDLINE(R) in-process and other non-indexed citations and Ovid MEDLINE(R), Ovid Healthstar, CINAHL, PsycINFO, all EBM reviews-Cochrane DSR, ACP Journal Club, DARE, CCTR, CMR, HTA, and NHSEED, and the ISI Web of Science, until October 2009; government web pages for statistics and other demographic data in countries where they were available; citation lists of relevant articles. 

**Review methods** 
Randomised controlled studies, interrupted time series analyses with a concurrent comparison group, studies with follow-up examinations (post-test questionnaires and monitoring suicide rates), and middle to high school-based curriculum studies, including both male and female participants, were included. 

**Results** 
36 potentially relevant studies were identified, eight of which met the inclusion criteria. Overall, statistically significant improvements were noted in knowledge, attitude, and help-seeking behaviour. A decrease in self reported ideation was reported in two studies. None reported on suicide rates. 

**Conclusion** 
Although evidence exists that school-based programmes to prevent suicide among adolescents improve knowledge, attitudes, and help-seeking behaviours, no evidence yet exists that these prevention programmes reduce suicide rates. Further well designed, controlled research is required before such programmes are instituted broadly to populations at risk.
AD  - [Cusimano, Michael D.] St Michaels Hosp, Injury Prevent Res Off, Keenan Res Ctr, Li Ka Shing Knowledge Inst, Toronto, ON M5C 3G7, Canada. [Cusimano, Michael D.] Univ Toronto, Toronto, ON, Canada. [Sameem, Mojib] McMaster Univ, Michael G DeGroote Sch Med, Hamilton, ON, Canada. Cusimano, MD (reprint author), St Michaels Hosp, Injury Prevent Res Off, Keenan Res Ctr, Li Ka Shing Knowledge Inst, 2 Queen St E,Suite 10-05, Toronto, ON M5C 3G7, Canada. injuryprevention@smh.toronto.on.ca
AN  - WOS:000286654800010
AU  - Cusimano,
AU  - M.
AU  - D.
AU  - Sameem,
AU  - M.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1136/ip.2009.025502
J2  - Inj. Prev.
KW  - IMPACT Public, Environmental &amp; Occupational Health
L1  - internal-pdf://1307684637/Cusimano-2011-The effectiveness of middle and.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 712GS Times Cited: 9 Cited Reference Count: 23 Cusimano, Michael D. Sameem, Mojib 9 B M J PUBLISHING GROUP LONDON INJURY PREV
PY  - 2011
SP  - 43-49
T2  - Injury Prevention
TI  - The effectiveness of middle and high school-based suicide prevention programmes for adolescents: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000286654800010http://injuryprevention.bmj.com/content/17/1/43.full.pdf
UR  - http://injuryprevention.bmj.com/content/injuryprev/17/1/43.full.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
This study was designed to quantitatively evaluate the effectiveness of motivational interviewing (MI) interventions for adolescent substance use behavior change. 

**METHOD: **
Literature searches of electronic databases were undertaken in addition to manual reference searches of identified review articles. Databases searched include PsycINFO, PUBMED/MEDLINE, and Educational Resources Information Center. Twenty-one independent studies, representing 5,471 participants, were located and analyzed. 

**RESULTS: **
An omnibus weighted mean effect size for all identified MI interventions revealed a small, but significant, posttreatment effect size (mean d = .173, 95% CI [.094, .252], n = 21). Small, but significant, effect sizes were observed at follow-up suggesting that MI interventions for adolescent substance use retain their effect over time. MI interventions were effective across a variety of substance use behaviors, varying session lengths, and different settings, and for interventions that used clinicians with different levels of education. 

**CONCLUSIONS: **
The effectiveness of MI interventions for adolescent substance use behavior change is supported by this meta-analytic review. In consideration of these results, as well as the larger literature, MI should be considered as a treatment for adolescent substance use.
AD  - Jensen,Chad D. Clinical Child Psychology Program, University of Kansas, KS, USA.
AN  - 21728400
AU  - Jensen,
AU  - C.
AU  - D.
AU  - Cushing,
AU  - C.
AU  - C.
AU  - Aylward,
AU  - B.
AU  - S.
AU  - Craig,
AU  - J.
AU  - T.
AU  - Sorell,
AU  - D.
AU  - M.
AU  - Steele,
AU  - R.
AU  - G.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/a0023992
DP  - Ovid Technologies
J2  - J Consult Clin Psychol
KW  - Adolescent *Behavior Therapy/mt [Methods] Counseling/mt [Methods] Humans *Interviews as Topic *Motivation *Substance-Related Disorders/th [Therapy] Treatment Outcome
LA  - English
M3  - Meta-Analysis Review
N1  - Jensen, Chad D Cushing, Christopher C Aylward, Brandon S Craig, James T Sorell, Danielle M Steele, Ric G
PY  - 2011
SP  - 433-40
T2  - Journal of Consulting &amp; Clinical Psychology
TI  - Effectiveness of motivational interviewing interventions for adolescent substance use behavior change: a meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21728400
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21728400&amp;id=doi:10.1037%2Fa0023992&amp;issn=0022-006X&amp;isbn=&amp;volume=79&amp;issue=4&amp;spage=433&amp;pages=433-40&amp;date=2011&amp;title=Journal+of+Consulting+%26+Clinical+Psychology&amp;atitle=Effectiveness+of+motivational+interviewing+interventions+for+adolescent+substance+use+behavior+change%3A+a+meta-analytic+review.&amp;aulast=Jensen&amp;pid=%3Cauthor%3EJensen+CD%3C%2Fauthor%3E%3CAN%3E21728400%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://psycnet.apa.org/journals/ccp/79/4/433.pdf
VL  - 79
ER  -
TY  - JOUR
AB  - **Background:** 
It has been suggested that impairments associated with autism spectrum disorders (ASD) may be partially explained by deficits of omega-3 fatty acids, and that supplementation of these essential fatty acids may lead to improvement of symptoms.

**Objectives:** 
To review the efficacy of omega-3 fatty acids for improving core features of ASD (for example, social interaction, communication, and stereotypies) and associated symptoms.&nbsp;

**Search methods:** 
We searched the following databases on 2 June 2010: CENTRAL (2010, Issue 2), MEDLINE (1950 to May Week 3 2010), EMBASE (1980 to 2010 Week 21), PsycINFO (1806 to current), BIOSIS (1985 to current), CINAHL (1982 to current), Science Citation Index (1970 to current), Social Science Citation Index (1970 to current), metaRegister of Controlled Trials (20 November 2008) and ClinicalTrials.gov (10 December 2010). Dissertation Abstracts International was searched on 10 December 2008, but was no longer available to the authors or editorial base in 2010.

**Selection criteria:** 
All randomised controlled trials of omega-3 fatty acids supplementation compared to placebo in individuals with ASD.Data collection and analysis: Three authors independently selected studies, assessed them for risk of bias and extracted relevant data. We conducted meta-analysis of the included studies for three primary outcomes (social interaction, communication, and stereotypy) and one secondary outcome (hyperactivity).

**Main results:** 
We included two trials with a total of 37 children diagnosed with ASD who were randomised into groups that received either omega-3 fatty acids supplementation or a placebo. We excluded six trials because they were either non-randomised controlled trials, did not contain a control group, or the control group did not receive a placebo. Overall, there was no evidence that omega-3 supplements had an effect on social interaction (mean difference (MD) 0.82, 95% confidence interval (CI) -2.84 to 4.48, I2 = 0%), communication (MD 0.62, 95% CI -0.89 to 2.14, I2 = 0%), stereotypy (MD 0.77, 95% CI -0.69 to 2.22, I2 = 8%), or hyperactivity (MD 3.46, 95% CI -0.79 to 7.70, I2 = 0%).

**Authors&#039; conclusions:** 
To date there is no high quality evidence that omega-3 fatty acids supplementation is effective for improving core and associated symptoms of ASD. Given the paucity of rigorous studies in this area, there is a need for large well-conducted randomised controlled trials that examine both high and low functioning individuals with ASD, and that have longer follow-up periods.
AN  - CD007992
AU  - James,
AU  - S.
AU  - Montgomery,
AU  - P.
AU  - Williams,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007992.pub2
KW  - Dietary Supplements
KW  - Child Development Disorders, Pervasive [diet therapy]
KW  - Docosahexaenoic Acids [administration &amp; dosage]
KW  - Eicosapentaenoic Acid [administration &amp; dosage]
KW  - Fatty Acids, Omega-3 [therapeutic use]
KW  - Interpersonal Relations
KW  - Randomized Controlled Trials as Topic
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Behav
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Omega-3 fatty acids supplementation for autism spectrum disorders (ASD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007992.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007992.pub2/asset/CD007992.pdf?v=1&amp;t=iw7kjfd1&amp;s=8b20574cc41cc490370be9105b6f19c058594c02
ER  -
TY  - JOUR
AB  - **Background: **
To review empirical studies of adverse drug reactions (ADRs) reported to be associated with the use of medications generally licensed for treatment of attention deficit hyperactivity disorder (ADHD) symptoms in the pediatric population. 

**Methods: **
PubMed, Embase, and PsycINFO databases were searched from origin until June 2011. Studies reporting ADRs from amphetamine derivates, atomoxetine, methylphenidate, and modafinil in children from birth to age 17 were included. Information about ADR reporting rates, age and gender of the child, type, and seriousness of ADRs, setting, study design, ADR assessors, authors, and funding sources were extracted.

**Results: **
The review identified 43 studies reporting ADRs associated with medicines for treatment of ADHD in clinical studies covering approximately 7000 children, the majority of 6- to 12-year-old boys, and particularly in the United States of America (USA). The most frequently reported ADRs were decrease in appetite, gastrointestinal pain, and headache. There were wide variations in reported ADR occurrence between studies of similar design, setting, included population, and type of medication. Reported ADRs were primarily assessed by the children/their parents, and very few ADRs were rated as being serious. A large number of children dropped out of studies due to serious ADRs, and therefore, the actual number of serious ADRs from use of psychostimulants is probably higher. A large number of studies were conducted by the same groups of authors and sponsored by the pharmaceutical companies manufacturing the respective medications. 

**Conclusion: **
Reported ADRs from use of psychostimulants in children were found in clinical trials of short duration. Since ADHD medications are prescribed for long-term treatment, there is a need for long-term safety studies. The pharmaceutical companies should make all information about ADRs reported for these medications accessible to the public, and further studies are needed on the impact of the link between researchers and the manufacturers of the respective products. 

&copy; 2011 Aagaard and Hansen, publisher and licensee Dove Medical Press Ltd.
AD  - (Aagaard, Hansen) Department of Pharmacology and Pharmacotherapy, Section for Social Pharmacy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark (Aagaard, Hansen) FKL-Research Centre for Quality in Medicine Use, Copenhagen, Denmark (Aagaard, Hansen) Danish Pharmacovigilance Research Project (DANPREP), Copenhagen, Denmark L. Aagaard, Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. E-mail: laa@farma.ku.dk
AN  - 2012053447
AU  - Aagaard,
AU  - L.
AU  - Hansen,
AU  - E.
AU  - H.
DA  - 15 Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2147/NDT.S26403
DP  - Ovid Technologies
KW  - Adverse drug reactions Attention deficit hyperactivity disorder Children Pharmacovigilance abnormal behavior/si [Side Effect] accidental injury/si [Side Effect] adverse drug reaction aggression agitation anorexia/si [Side Effect] anxiety asthenia/si [Si
L1  - internal-pdf://1177878979/Aagaard-2011-The occurrence of adverse drug re.pdf
LA  - English
M3  - Review
PY  - 2011
SP  - 729-744
T2  - Neuropsychiatric Disease and Treatment
TI  - The occurrence of adverse drug reactions reported for attention deficit hyperactivity disorder (ADHD) medications in the pediatric population: A qualitative review of empirical studies
UR  - https://www.dovepress.com/getfile.php?fileID=11628 http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed10&amp;AN=2012053447 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:&amp;issn=1176-6328&amp;isbn=&amp;volume=7&amp;issue=1&amp;spage=729&amp;pages=729-744&amp;date=2011&amp;title=Neuropsychiatric+Disease+and+Treatment&amp;atitle=The+occurrence+of+adverse+drug+reactions+reported+for+attention+deficit+hyperactivity+disorder+%28ADHD%29+medications+in+the+pediatric+population%3A+A+qualitative+review+of+empirical+studies&amp;aulast=Aagaard&amp;pid=%3Cauthor%3EAagaard+L.%3C%2Fauthor%3E%3CAN%3E2012053447%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3Ehttp://www.dovepress.com/getfile.php?fileID=11628
UR  - https://www.dovepress.com/getfile.php?fileID=11628
VL  - 7
ER  -
TY  - JOUR
AB  - The aim of this article was to analyze systematically literature information published in English (between 1966 and January 2011) on the efficacy of antidepressants in pediatric obsessive-compulsive disorder. 

Data were identified through different databases by using variously combined patterns of search terms. 

Searches provided 85 articles, excluding duplicates, but only articles reporting primary data on use of antidepressants in this specific disorder were reviewed. Fifty-nine articles were excluded because they did not report primary efficacy data or investigated patients with different psychiatric diagnosis. Twenty-five electronically recognized articles met the inclusion criteria. Two additional studies, available as congress communication, were identified by manually checking the references&#039; list of electronically identified articles.
 
Reviewed studies show several methodological biases (the lack/limited number of long-term trials and head-to-head comparisons and the inclusion of patients who continued different forms of psychotherapy), which make it difficult to individuate the best pharmacological strategy. 

Despite these limitations, evidence-based information suggests that clomipramine and sertraline, especially for long-term treatments, should be considered as first-choice agents for treating obsessive-compulsive disorder at onset during childhood or adolescence.
AD  - Gentile,Salvatore. Department of Mental Health ASL Salerno, Mental Health Center Cava de&#039; Tirreni, Salerno, Italy. salvatore_gentile@alice.it
AN  - 21869690
AU  - Gentile,
AU  - S.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/jcp.0b013e31822bb1ff
DP  - Ovid Technologies
J2  - J Clin Psychopharmacol
KW  - Adolescent Antidepressive Agents/ad [Administration &amp; Dosage] *Antidepressive Agents/tu [Therapeutic Use] Child Clomipramine/ad [Administration &amp; Dosage] Clomipramine/tu [Therapeutic Use] Humans *Obsessive-Compulsive Disorder/dt [Drug Therapy] Obsessive
L1  - internal-pdf://1000958308/Gentile-2011-Efficacy of antidepressant medica.pdf
LA  - English
M3  - Review
N1  - Gentile, Salvatore
PY  - 2011
SP  - 625-32
T2  - Journal of Clinical Psychopharmacology
TI  - Efficacy of antidepressant medications in children and adolescents with obsessive-compulsive disorder: a systematic appraisal
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21869690
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21869690&amp;id=doi:10.1097%2FJCP.0b013e31822bb1ff&amp;issn=0271-0749&amp;isbn=&amp;volume=31&amp;issue=5&amp;spage=625&amp;pages=625-32&amp;date=2011&amp;title=Journal+of+Clinical+Psychopharmacology&amp;atitle=Efficacy+of+antidepressant+medications+in+children+and+adolescents+with+obsessive-compulsive+disorder%3A+a+systematic+appraisal.&amp;aulast=Gentile&amp;pid=%3Cauthor%3EGentile+S%3C%2Fauthor%3E%3CAN%3E21869690%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://graphics.tx.ovid.com/ovftpdfs/FPDDNCLBMEJCKF00/fs046/ovft/live/gv023/00004714/00004714-201110000-00013.pdf
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCDCDBALNL00/fs046/ovft/live/gv023/00004714/00004714-201110000-00013.pdf
VL  - 31
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Previous studies comparing atomoxetine and methylphenidate to treat ADHD symptoms have been equivocal. This noninferiority meta-analysis compared core ADHD symptom response between atomoxetine and methylphenidate in children and adolescents. 

**METHOD:**
Selection criteria included randomized, controlled design; duration 6 weeks; and assessment of ADHD Rating Scale-IV-Parent Version: Investigator Administered and Scored (ADHDRS) scores. Six-week response rates, defined as &gt;40% reduction in ADHDRS total score, were compared using a noninferiority margin of -15%. 

**RESULTS: **
Seven studies met inclusion criteria (N = 1,368). After 6 weeks, 53.6% (95% confidence interval [CI] 48.6%-58.4%) of atomoxetine-treated patients (n = 811) had responded compared with 54.4% (47.6%-61.1%) for methylphenidate (n = 557), with atomoxetine demonstrating noninferiority to methylphenidate (absolute difference -0.9%, 95% CI -9.2%-7.5%). 

**CONCLUSION: **
After 6 weeks of treatment atomoxetine and methylphenidate had comparable efficacy in reducing core ADHD symptoms in children and adolescents.
AD  - Hazell,Philip L. Discipline of Psychological Medicine, Concord Clinical School, The University of Sydney, Australia. philip.hazell@sswahs.nsw.gov.au
AN  - 20837981
AU  - Hazell,
AU  - P.
AU  - L.
AU  - Kohn,
AU  - M.
AU  - R.
AU  - Dickson,
AU  - R.
AU  - Walton,
AU  - R.
AU  - J.
AU  - Granger,
AU  - R.
AU  - E.
AU  - Wyk,
AU  - G.
AU  - W.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1087054710379737
DP  - Ovid Technologies
J2  - J Atten Disord
KW  - Adolescent *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] *Central Nervous System Stimulants/tu [Therapeutic Use] Child Female Humans Male *Methylphenidate/tu [Therapeutic Use] *Propylamines/tu [Therapeutic Use] Randomized Controlled T
LA  - English
M3  - Comparative Study Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Hazell, Philip L Kohn, Michael R Dickson, Ruth Walton, Richard J Granger, Renee E Wyk, Gregory W van
PY  - 2011
SP  - 674-83
T2  - Journal of Attention Disorders
TI  - Core ADHD symptom improvement with atomoxetine versus methylphenidate: a direct comparison meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=20837981 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20837981&amp;id=doi:10.1177%2F1087054710379737&amp;issn=1087-0547&amp;isbn=&amp;volume=15&amp;issue=8&amp;spage=674&amp;pages=674-83&amp;date=2011&amp;title=Journal+of+Attention+Disorders&amp;atitle=Core+ADHD+symptom+improvement+with+atomoxetine+versus+methylphenidate%3A+a+direct+comparison+meta-analysis.&amp;aulast=Hazell&amp;pid=%3Cauthor%3EHazell+PL%3C%2Fauthor%3E%3CAN%3E20837981%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://jad.sagepub.com/content/15/8/674http://jad.sagepub.com/content/15/8/674.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/1087054710379737?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 15
ER  -
TY  - JOUR
AB  - **Objective: **
A growing body of literature has documented pediatric bipolar disorder to be a severely impairing form of psychopathology. However, concerns remain as to the inadequacy of the extant literature on its pharmacotherapy. Furthermore, treatment studies have not been systematically reviewed for treatment effects on core and associated symptoms. Thus, a systematic evaluation and synthesis of the available literature on the efficacy of antimanic pharmacotherapy for pediatric bipolar disorder on symptoms of mania, depression, and attention-deficit/hyperactivity disorder was undertaken. 

**Method: **
A systematic search was conducted through PubMed from 1989 through 2010 for open-label and randomized controlled trials published in English on the pharmacotherapy of pediatric mania. 

**Results:**
There have been 46 open-label (n = 29) and randomized (n = 17) clinical trials of antimanic agents in pediatric bipolar disorder encompassing 2,666 subjects that evaluated a range of therapeutic agents, including traditional mood stabilizers, other anticonvulsants, second-generation antipsychotics, and naturopathic compounds. This literature has documented that the available armamentarium has different levels of efficacy in the treatment of pediatric mania. Because all psychotropic classes are associated with important adverse effects, a careful risk-benefit analysis is warranted when initiating pharmacologic treatment with any of these compounds. In the limited data available, the effects of antimanic agents on depression and symptoms of attention-deficit/hyperactivity disorder have been, in general, modest. Few studies have evaluated the effects of antimanic agents in children younger than 10 years. 

**Conclusions: **
A substantial body of scientific literature has evaluated the safety and efficacy of various medicines and drug classes in the treatment of mania in pediatric bipolar disorder. More work is needed to assess the safety and efficacy of psychotropic drugs in children younger than 10 years, to further evaluate the efficacy of naturopathic compounds, and to further evaluate the effects of antimanic treatments for the management of depression and attention-deficit/hyperactivity disorder. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - Yvonne Biederman, Joseph: jbiederman@partners.org Biederman, Joseph: Massachusetts General Hospital, 55 Fruit Street, YAW 6A, Boston, US, 02114, jbiederman@partners.org Liu, Howard Y.: University of Nebraska Medical Center, Omaha, NE, US Potter, Mona P.: McLean Hospital, Belmont, MA, US Woodworth, K. Yvonne: Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, MA, US Yorks, Dayna M.: Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, Boston, MA, US Petty, Carter R.: Massachusetts General Hospital, Boston, MA, US Wozniak, Janet R.: Massachusetts General Hospital, MA, US Faraone, Stephen V.: State University of New York (SUNY), Upstate Medical University, Syracuse, NY, US Biederman, Joseph: Clinical and Research Program in Pediatric Psychopharmacology, Massachusetts General Hospital, MA, US
AN  - 2011-16804-008
AU  - Liu,
AU  - H.
AU  - Y.
AU  - Potter,
AU  - M.
AU  - P.
AU  - Woodworth,
AU  - K.
AU  - Yorks,
AU  - D.
AU  - M.
AU  - Petty,
AU  - C.
AU  - R.
AU  - Wozniak,
AU  - J.
AU  - R.
AU  - Faraone,
AU  - S.
AU  - V.
AU  - Biederman,
AU  - J.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jaac.2011.05.011
DP  - Ovid Technologies
KW  - pharmacologic treatments, drug therapy, pediatric bipolar disorder, side effects, symptoms, mania, depression, attention deficit hyperactivity disorder *Bipolar Disorder *Drug Therapy *Pediatrics *Side Effects (Drug) *Symptoms Attention Deficit Disorder
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2011
SP  - e1-e39, 749-762
T2  - Journal of the American Academy of Child &amp; Adolescent Psychiatry
TI  - Pharmacologic treatments for pediatric bipolar disorder: A review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2011-16804-008 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jaac.2011.05.011&amp;issn=0890-8567&amp;isbn=&amp;volume=50&amp;issue=8&amp;spage=e1&amp;pages=e1-e39%2C+749-762&amp;date=2011&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Pharmacologic+treatments+for+pediatric+bipolar+disorder%3A+A+review+and+meta-analysis.&amp;aulast=Liu&amp;pid=%3Cauthor%3ELiu%2C+Howard+Y%3C%2Fauthor%3E%3CAN%3E2011-16804-008%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0890856711004448/1-s2.0-S0890856711004448-main.pdf?_tid=4164864e-1674-11e5-aa7d-00000aab0f02&amp;acdnat=1434712607_a9c57aab2e1f2e3929b847d9349b15a6
VL  - 50
ER  -
TY  - JOUR
AB  - **Background **
Cigarette smoking is one of the leading causes of preventable death in the world. Decisions to smoke are often made within a broad social context and therefore community interventions using coordinated, multi-component programmes may be effective in influencing the smoking behaviour of young people.

**Objectives** 
To determine the effectiveness of multi-component community based interventions in influencing smoking behaviour, which includes preventing the uptake of smoking in young people. Search strategy The Tobacco Addiction group&#039;s specialised register, Medline and other health, psychology and public policy electronic databases were searched, the bibliographies of identified studies were checked and raw data was requested from study authors. Searches were updated in August 2010. Selection criteria Randomized and non randomized controlled trials that assessed the effectiveness of multi-component community interventions compared to no intervention or to single component or school-based programmes only. Reported outcomes had to include smoking behaviour in young people under the age of 25 years. 

**Data collection and analysis **
Information relating to the characteristics and the content of community interventions, participants, outcomes and methods of the study was extracted by one reviewer and checked by a second. Studies were combined in a meta-analysis where possible and reported in narrative synthesis in text and table. 

**Main results**
Twenty-five studies were included in the review and sixty-eight studies did not meet all of the inclusion criteria. All studies used a controlled trial design, with fifteen using random allocation of schools or communities. One study reported a reduction in short-term smoking prevalence (twelve months or less), while nine studies detected significant long-term effects. Two studies reported significantly lower smoking rates in the control population while the remaining thirteen studies showed no significant difference between groups. Improvements were seen in secondary outcomes for intentions to smoke in six out of eight studies, attitudes in five out of nine studies, perceptions in two out of six studies and knowledge in three out of six studies, while significant differences in favour of the control were seen in one of the nine studies assessing attitudes and one of six studies assessing perceptions. 

**Authors&#039; conclusions **
There is some evidence to support the effectiveness of community interventions in reducing the uptake of smoking in young people, but the evidence is not strong and contains a number of methodological flaws.
AD  - [Carson, Kristin V.; Brinn, Malcolm P.; Labiszewski, Nadina A.] Queen Elizabeth Hosp, Clin Practice Unit, Adelaide, SA 5011, Australia. [Esterman, Adrian J.] Univ S Australia, Adelaide, SA 5001, Australia. [Chang, Anne B.] Charles Darwin Univ, Menzies Sch Hlth Res, Casuarina, Australia. [Smith, Brian J.] Univ Adelaide, Dept Med, Queen Elizabeth Hosp, Adelaide, SA 5001, Australia. Carson, KV (reprint author), Queen Elizabeth Hosp, Clin Practice Unit, 4A Main Bldg,28 Woodville Rd,Woodville S, Adelaide, SA 5011, Australia. kristin.carson@health.sa.gov.au
AN  - WOS:000292554305006
AU  - Carson,
AU  - K.
AU  - V.
AU  - Brinn,
AU  - M.
AU  - P.
AU  - Labiszewski,
AU  - N.
AU  - A.
AU  - Esterman,
AU  - A.
AU  - J.
AU  - Chang,
AU  - A.
AU  - B.
AU  - Smith,
AU  - B.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD001291.pub2
J2  - Cochrane Database Syst Rev.
KW  - Health Promotion Adolescent Age Factors Smoking [prevention &amp; control] Adult Child Female Humans Male KARELIA-YOUTH-PROJECT ADOLESCENT TOBACCO-USE HISPANIC MIGRANT ADOLESCENTS DRUG-ABUSE PREVENTION RANDOMIZED CONTROLLED-TRIAL FRAMEWORK APPROACH ESFA HEA
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 789YB Times Cited: 9 Cited Reference Count: 166 Carson, Kristin V. Brinn, Malcolm P. Labiszewski, Nadina A. Esterman, Adrian J. Chang, Anne B. Smith, Brian J. Chang, Anne/F-2066-2013; Esterman, Adrian/D-1042-2009 Respiratory Medicine Unit, The Queen Elizabeth Hospital, Australia; Australasian Cochrane Airways Group Network Scholarship, Australia Internal sourcesRespiratory Medicine Unit, The Queen Elizabeth Hospital, Australia.External sourcesAustralasian Cochrane Airways Group Network Scholarship, Australia. 9 WILEY-BLACKWELL MALDEN COCHRANE DB SYST REV
PY  - 2011
SP  - 140
T2  - Cochrane Database of Systematic Reviews
TI  - Community interventions for preventing smoking in young people
UR  - &lt;Go to ISI&gt;://WOS:000292554305006http://onlinelibrary.wiley.com/store/10.1002/14651858.CD001291.pub2/asset/CD001291.pdf?v=1&amp;t=ib7t4nds&amp;s=279352089c274bc5741f2ea1a10c5dde07bce776
ER  -
TY  - JOUR
AB  - **Objective: **
To assess the impact of treatment foster care (TFC) on psychosocial and behavioral outcomes, delinquency, placement stability, and discharge status for children and adolescents who, for reasons of severe medical, social, psychological and behavioural problems, were placed in out-of-home care in restrictive settings or at risk of placement in such settings. 

**Method: **
Electronic bibliographic databases, web searches, and article reference lists were used to identify randomized controlled trials (RCTs) investigating the effectiveness of TFC with children and young people. The Cochrane Collaboration&#039;s criteria were used to assess the methodological quality of studies that met the inclusion criteria. Wherever possible, extracted outcome data from similar studies were synthesized with random effects meta-analyses. 

**Results:**
A total of 5 studies including 390 participants were included in this review. Data suggest that TFC may be a useful intervention for children and young people with complex emotional, psychological, and behavioural need, who are at risk of placements in nonfamily settings that restrict their liberty and opportunities for social inclusion. 

**Conclusion: **
Although the inclusion criteria for this systematic review set a study design threshold higher than that of previous reviews, the findings mirror those of earlier reviews. While the results of individual studies generally indicate that TFC is a promising intervention for children and youth experiencing mental health problems, behavioral problems, or problems of delinquency, the evidence base is not robust and more research is needed due to the limited number of studies in this area.
AD  - [Turner, William] Univ Bristol, Sch Policy Studies, Bristol BS8 1TZ, Avon, England. [Macdonald, Geraldine] Queens Univ Belfast, Belfast, Antrim, North Ireland. Turner, W (reprint author), Univ Bristol, Sch Policy Studies, 8 Priory Rd, Bristol BS8 1TZ, Avon, England. w.turner@bristol.ac.uk
AN  - WOS:000293572000001
AU  - Turner,
AU  - W.
AU  - Macdonald,
AU  - G.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD005649.pub2
J2  - Res. Soc. Work. Pract.
KW  - mental health behavioral problems delinquency foster care child welfare systematic review RANDOMIZED CLINICAL-TRIAL JUVENILE JUSTICE SYSTEM 2-YEAR FOLLOW-UP BEHAVIORAL-DISORDERS FAMILY CARE PROGRAM INTERVENTION GIRLS ADOLESCENTS SERVICES Social Work
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 803HI Times Cited: 1 Cited Reference Count: 74 Turner, William Macdonald, Geraldine 1 SAGE PUBLICATIONS INC THOUSAND OAKS RES SOCIAL WORK PRAC
PY  - 2011
SP  - 501-527
T2  - Research on Social Work Practice
TI  - Treatment Foster Care for Improving Outcomes in Children and Young People: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000293572000001http://rsw.sagepub.com/content/21/5/501http://rsw.sagepub.com/content/21/5/501.full.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - **Background: **
Despite recent advances in the understanding and treatment of self-harm, poor engagement with therapy remains a serious problem. 

**Aims: **
To investigate whether offering specific psychological treatment (SPT) leads to better engagement than offering treatment as usual (TAU) in adolescents who have self-harmed. 

**Methods: **
Data sources were identified by searching Medline, PsychINFO, EMBASE, and PubMed for randomized controlled trials comparing SPT versus TAU in adolescents presenting with self-harm. 

**Results: **
Seven studies met inclusion criteria, and six were entered into the meta-analysis. There was no statistically significant difference between the number of subjects not completing four or more sessions of an SPT (27.7%, 70/253) than TAU (43.3%, 106/245), RR = 0.71 (95% CI: 0.49-1.05). 

**Conclusions: **
Engaging adolescents with psychological treatment is necessary although not sufficient to achieve treatment goals. Further research is needed to develop tools for maximizing engagement.
AD  - [Ougrin, Dennis] Kings Coll London, Inst Psychiat, Dept Child &amp; Adolescent Psychiat, London SE5 8AF, England. [Latif, Saqib] S London &amp; Maudsley NHS Fdn Trust, London, England. Ougrin, D (reprint author), Kings Coll London, Inst Psychiat, Dept Child &amp; Adolescent Psychiat, PO 85,De Crespigny Pk, London SE5 8AF, England. dennis.ougrin@kcl.ac.uk
AN  - WOS:000292005300004
AU  - Ougrin,
AU  - D.
AU  - Latif,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1027/0227-5910/a000060
J2  - Crisis
KW  - self-harm adolescents engagement psychological treatment RANDOMIZED CONTROLLED-TRIAL SUICIDE ATTEMPTERS FOLLOW-UP TREATMENT ADHERENCE EMPIRICAL-EVIDENCE CLINICAL-TRIALS GROUP-THERAPY YOUNG-PEOPLE INTERVENTION REPLICATION Psychiatry Psychology, Multidisc
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 782JT Times Cited: 14 Cited Reference Count: 44 Ougrin, Dennis Latif, Saqib 14 HOGREFE &amp; HUBER PUBLISHERS GOTTINGEN CRISIS
PY  - 2011
SP  - 74-80
T2  - Crisis-the Journal of Crisis Intervention and Suicide Prevention
TI  - Specific Psychological Treatment Versus Treatment as Usual in Adolescents with Self-Harm Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000292005300004
VL  - 32
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Evidence-based best practices for incorporation into an optimal multilevel intervention for suicide prevention should be identifiable in the literature. 

**AIMS: **
To identify effective interventions for the prevention of suicidal behavior.

**METHODS:**
Review of systematic reviews found in the Pubmed, Cochrane, and DARE databases. Steps include risk-of-bias assessment, data extraction, summarization of best practices, and identification of synergistic potentials of such practices in multilevel approaches. 

**RESULTS: **
Six relevant systematic reviews were found. Best practices identified as effective were as follows: training general practitioners (GPs) to recognize and treat depression and suicidality, improving accessibility of care for at-risk people, and restricting access to means of suicide. Although no outcomes were reported for multilevel interventions or for synergistic effects of multiple interventions applied together, indirect support was found for possible synergies in particular combinations of interventions within multilevel strategies. 

**CONCLUSIONS: **
A number of evidence-based best practices for the prevention of suicide and suicide attempts were identified. Research is needed on the nature and extent of potential synergistic effects of various preventive activities within multilevel interventions.
AN  - 21945840
AU  - van
AU  - der
AU  - Feltz-Cornelis,
AU  - C.
AU  - M.
AU  - Sarchiapone,
AU  - M.
AU  - Postuvan,
AU  - V.
AU  - Volker,
AU  - D.
AU  - Roskar,
AU  - S.
AU  - Grum,
AU  - A.
AU  - T.
AU  - Carli,
AU  - V.
AU  - McDaid,
AU  - D.
AU  - O&#039;Connor,
AU  - R.
AU  - Maxwell,
AU  - M.
AU  - Ibelshauser,
AU  - A.
AU  - Van
AU  - Audenhove,
AU  - C.
AU  - Scheerder,
AU  - G.
AU  - Sisask,
AU  - M.
AU  - Gusmao,
AU  - R.
AU  - Hegerl,
AU  - U.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1027/0227-5910/a000109
L1  - internal-pdf://2069635516/van der Feltz-C-2011-Best practice elements of.pdf
PY  - 2011
SP  - 319-33
T2  - Crisis: Journal of Crisis Intervention &amp; Suicide
TI  - Best practice elements of multilevel suicide prevention strategies: a review of systematic reviews
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=21945840
VL  - 32
ER  -
TY  - JOUR
AB  - A two-part systematic review was undertaken to assess the effectiveness of token economies in increasing rates of appropriate classroom behavior for students demonstrating behavioral difficulties. 

The first part of the review utilized the recently published What Works Clearinghouse (WWC) standards for evaluating single-subject research to determine the extent to which eligible studies demonstrated sufficient evidence to classify the token economy as an evidence-based practice.

The second part of the review employed meta-analytic techniques across four different types of effect sizes to evaluate the quantitative strength of the findings. Methodological strengths and weaknesses across the studies were systematically investigated. 

Results indicated that the extant research on token economies does not provide sufficient evidence to be deemed best-practice based on the WWC criteria. Published by Elsevier Ltd. on behalf of Society for the Study of School Psychology.
AD  - [Maggin, Daniel M.] Univ Connecticut, Neag Sch Educ, Ctr Behav Educ &amp; Res, Storrs, CT 06269 USA. Maggin, DM (reprint author), Univ Connecticut, Neag Sch Educ, Ctr Behav Educ &amp; Res, 249 Glenbrook Rd, Storrs, CT 06269 USA. daniel.maggin@uconn.edu
AN  - WOS:000296038400003
AU  - Maggin,
AU  - D.
AU  - M.
AU  - Chafouleas,
AU  - S.
AU  - M.
AU  - Goddard,
AU  - K.
AU  - M.
AU  - Johnson,
AU  - A.
AU  - H.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jsp.2011.05.001
J2  - J. Sch. Psychol.
KW  - Classroom management Contingency management Quantitative synthesis Single-subject Systematic review Token economy SINGLE-SUBJECT RESEARCH TREATMENT INTEGRITY SOCIAL VALIDITY ACADEMIC-PERFORMANCE REINFORCEMENT SYSTEM TEACHER ATTENTION SPECIAL-EDUCATION R
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 835LR Times Cited: 17 Cited Reference Count: 98 Maggin, Daniel M. Chafouleas, Sandra M. Goddard, Katelyn M. Johnson, Austin H. 18 PERGAMON-ELSEVIER SCIENCE LTD OXFORD J SCHOOL PSYCHOL
PY  - 2011
SP  - 529-554
T2  - Journal of School Psychology
TI  - A systematic evaluation of token economies as a classroom management tool for students with challenging behavior
UR  - &lt;Go to ISI&gt;://WOS:000296038400003http://ac.els-cdn.com/S0022440511000495/1-s2.0-S0022440511000495-main.pdf?_tid=0ef6993c-1678-11e5-8388-00000aab0f02&amp;acdnat=1434714240_b53df4c126099ff2aedbb5518602fdd9
VL  - 49
ER  -
TY  - JOUR
AB  - Excitement and controversy have surrounded the effectiveness of Early Intensive Behavioral Intervention (EIBI) for young children with autism. 

The purpose of this meta-analysis was to investigate the effectiveness of EIBI based on applied behavior analysis in young children with Autism Spectrum Disorders (ASD). 

There were 11 studies with 344 children with ASD. Quality of studies was assessed using the Downs and Black Checklist. Experimental groups who received EIBI outperformed the control groups on IQ, non-verbal IQ, expressive and receptive language and adaptive behavior. 

Differences between the experimental and control groups were 4.96-15.21 points on standardized tests. These results strongly support the effectiveness of EIBI. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Peters-Scheffer, Nienke: n.peters@pwo.ru.nl; Didden, Robert: r.didden@pwo.ru.nl; Korzilius, Hubert: h.korzilius@fm.ru.nl; Sturmey, Peter: psturmey@gmail.com Peters-Scheffer, Nienke: Behavioural Science Institute, Radboud University Nijmegen, PO Box 9104, Nijmegen, Netherlands, 6500 HE, n.peters@pwo.ru.nl Peters-Scheffer, Nienke: Behavioural Science Institute, Radboud University Nijmegen, Nijmegen, Netherlands Didden, Robert: Behavioural Science Institute, Radboud University Nijmegen, Nijmegen, Netherlands Korzilius, Hubert: Institute for Management Research, Radboud University Nijmegen, Nijmegen, Netherlands Sturmey, Peter: Queens College, City University of New York, Flushing, NY, US
AN  - 2010-22960-004
AU  - Peters-Scheffer,
AU  - N.
AU  - Didden,
AU  - R.
AU  - Korzilius,
AU  - H.
AU  - Sturmey,
AU  - P.
DA  - Jan-Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.rasd.2010.03.011
DP  - Ovid Technologies
KW  - program effectiveness, early intervention programs, children, autism spectrum disorders *Early Intervention *Pervasive Developmental Disorders *Program Evaluation Developmental Disorders &amp; Autism [3250] Health &amp; Mental Health Treatment &amp; Prevention [330
LA  - English
M3  - Meta Analysis
PY  - 2011
SP  - 60-69
T2  - Research in Autism Spectrum Disorders
TI  - A meta-analytic study on the effectiveness of comprehensive ABA-based early intervention programs for children with Autism Spectrum Disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2010-22960-004 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.rasd.2010.03.011&amp;issn=1750-9467&amp;isbn=&amp;volume=5&amp;issue=1&amp;spage=60&amp;pages=60-69&amp;date=2011&amp;title=Research+in+Autism+Spectrum+Disorders&amp;atitle=A+meta-analytic+study+on+the+effectiveness+of+comprehensive+ABA-based+early+intervention+programs+for+children+with+Autism+Spectrum+Disorders.&amp;aulast=Peters-Scheffer&amp;pid=%3Cauthor%3EPeters-Scheffer%2C+Nienke%3C%2Fauthor%3E%3CAN%3E2010-22960-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1750946710000498/1-s2.0-S1750946710000498-main.pdf?_tid=a16ef964-167b-11e5-8949-00000aab0f6c&amp;acdnat=1434715775_504c0150903f7c805890f918c2fd4a29
VL  - 5
ER  -
TY  - JOUR
AB  - **Objectives:** 
To report the state of the high-quality evidence on the impacts of YEPs on adolescents&rsquo; (ages 10-19) sense of self-efficacy and self-esteem, as well as other social and behavioral outcomes. To determine if the available evidence indicates best practices among YEPs or differential effects according to particular subgroups of adolescents. To identify directions for further research. 

**Search strategy:** 
The investigators conducted an international search that included twelve major academic electronic databases, twelve additional relevant institutional web-based publication databases, and a professional outreach for published and unpublished evaluations. 

**Selection criteria:** 
Randomized controlled trials or quasi-experimental trials using a prospectively assigned control group. Controls could have included no intervention, wait-list, or a comparison intervention without a significant empowerment component. Interventions must have regularly involved youth in program decision-making and met other basic youth empowerment standards. The review included interventions outside of formal education, juvenile detention, residential, and therapeutic systems. 

**Data collection and analaysis:** 8,789 citations were identified and screened independently and crosschecked by two reviewers. Sixty-eight studies were reviewed in-depth.

**Results:** 
Three studies met the review&rsquo;s full inclusion criteria; two of which measured self-efficacy outcomes that could be aggregated in a meta-analysis. The limited data meta-analyzed did not show a combined intervention effect on self-efficacy (z = 1.21; 95% CI -0.12 to 0.49). None of the three studies independently showed significant intervention effects on the review&rsquo;s primary outcomes. Mixed effects were demonstrated by results for secondary outcomes. There was no evidence of harm, in that no study&rsquo;s results revealed statistically significant adverse intervention effects for any of its measured outcomes.

**Authors&#039; conclusions:** 
The review reveals an insufficient evidence-base from experimental or quasi-experimental studies to substantiate the expectation that YEPs have an impact on developmental assets such as self-efficacy and self-esteem. Further research into YEPs using rigorous impact study designs is needed. Researchers should further develop methods and measures to enable high-quality, mixed-methods process studies to complement impact studies of YEPs so as to provide more useful evidence for practitioners and policy-makers.
AU  - Morton,
AU  - M.
AU  - Montgomery,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2011.5
KW  - Community participation
KW  - Empowerment
KW  - Self discipline
KW  - Self esteem
KW  - Youth
KW  - Adolescents
PY  - 2011
T2  - Campbell Systematic Reviews
TI  - Youth Empowerment Programs for Improving Self-Efficacy and Self-Esteem of Adolescents: A Systematic Review
ER  -
TY  - JOUR
AB  - **Purpose:** 
The purpose of this systematic literature review is to assess the effectiveness of substance abuse treatment on alcohol and marijuana use for juvenile offenders based on existing quasi-experimental and experimental research. Additionally, a secondary aim is to compare the effects of individual-based interventions to family-based interventions. 

**Methods:** A systematic search of literature and electronic databases through 2010 generated five experimental or quasi-experimental studies that assessed alcohol outcomes for juvenile offenders and five experimental or quasi-experimental studies that assessed marijuana outcomes for juvenile offenders. 

**Results:** Overall, substance abuse treatment appears to have a small to moderate effect on alcohol and marijuana reduction for juvenile offenders. Interventions that showed the most promise were Multisystemic Therapy, Multidimensional Treatment Foster Care, Teaching Family, and Life Skills Training. Individual-based interventions and family-based interventions had similar small to moderate effects on alcohol and marijuana use. 

**Conclusion:** This review highlights several promising interventions for this high-risk population; however, further rigorous study is desperately needed to provide a better understanding of what works best in reducing substance use among juvenile offenders. 

(C) 2011 Elsevier Ltd. All rights reserved.
AD  - [Tripodi, Stephen J.] Florida State Univ, Coll Social Work, Tallahassee, FL 32306 USA. [Bender, Kimberly] Univ Denver, Grad Sch Social Work, Denver, CO 80208 USA. Tripodi, SJ (reprint author), Florida State Univ, Coll Social Work, Tallahassee, FL 32306 USA. stripodi@fsu.edu
AN  - WOS:000291767900008
AU  - Tripodi,
AU  - S.
AU  - J.
AU  - Bender,
AU  - K.
DA  - May-Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jcrimjus.2011.02.007
J2  - J. Crim. Justice
KW  - RANDOMIZED CLINICAL-TRIAL ADOLESCENT MARIJUANA USE USE TREATMENT OUTCOMES TREATMENT FOSTER-CARE MULTISYSTEMIC THERAPY DRUG-ABUSE PSYCHIATRIC COMORBIDITY FOLLOW-UP ALCOHOL FAMILY Criminology &amp; Penology
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 779HE Times Cited: 7 Cited Reference Count: 50 Tripodi, Stephen J. Bender, Kimberly 7 PERGAMON-ELSEVIER SCIENCE LTD OXFORD J CRIM JUST SI
PY  - 2011
SP  - 246-252
T2  - Journal of Criminal Justice
TI  - Substance abuse treatment for juvenile offenders: A review of quasi-experimental and experimental research
UR  - &lt;Go to ISI&gt;://WOS:000291767900008http://ac.els-cdn.com/S0047235211000286/1-s2.0-S0047235211000286-main.pdf?_tid=7dc41896-1671-11e5-84dc-00000aacb362&amp;acdnat=1434711420_6511a399e932f04bb55e7a3bb1704597
VL  - 39
ER  -
TY  - JOUR
AB  - **Background **
Alcohol misuse in young people is a cause of concern for health services, policy makers, prevention workers, and criminal justice system, youth workers, teachers, and parents. 

**Objectives **
To systematically review evidence on the effectiveness of universal multi-component prevention programs in preventing alcohol misuse in school-aged children up to 18 years of age. To update a part of a previously published Cochrane systematic review. 

**Search strategy **
Relevant evidence (up to 2002) was selected from the previous Cochrane review. Later studies, to July 2010, were identified from MEDLINE, Cochrane Central Register of Controlled Trials, EMBASE, Project CORK, and PsycINFO. Selection criteria Randomized trials evaluating universal multi-component prevention programs (intervention delivered in more than one setting) and reporting outcomes for alcohol use in students 18 years of age or younger were included. Two reviewers screened titles/abstracts and full text of identified records. 

**Data collection and analysis **
Two reviewers extracted relevant data independently using an a priori defined extraction form. Risk of bias was assessed. 

**Main results **
20 parallel-group trials were included. The reporting quality of trials was poor, only 25% and 5% of them reporting adequate method of randomisation and program allocation concealment, respectively. Incomplete data was adequately addressed in about half of the trials and this information was unclear for about 20% of the trials. Due to extensive heterogeneity across interventions, populations, and outcomes, the results were summarized only qualitatively. 12 of the 20 trials showed some evidence of effectiveness compared to a control or other intervention group, with persistence of effects ranging from 3 months to 3 years. Of the remaining 8 trials, one trial reported significant effects using one-tailed tests and 7 trials reported no significant effects of the multi-component interventions for reducing alcohol misuse. Assessment of the additional benefit of multiple versus single component interventions was possible in 7 trials with multiple arms. Only one of the 7 trials clearly showed a benefit of components delivered in more than one setting. 

**Authors&#039; conclusions **
There is some evidence that multi-component interventions for alcohol misuse prevention in young people can be effective. However, there is little evidence that interventions with multiple components are more effective than interventions with single components.
AD  - [Foxcroft, David R.] Oxford Brookes Univ, Sch Hlth &amp; Social Care, Oxford OX3 0FL, England. [Tsertsvadze, Alexander] Univ Ottawa Evidence Based Practice Ctr, Clin Epidemiol Methods Ctr, Ottawa Hosp Res Inst, Ottawa, ON, Canada. Foxcroft, DR (reprint author), Oxford Brookes Univ, Sch Hlth &amp; Social Care, Marston Rd,Jack Straws Lane, Oxford OX3 0FL, England. david.foxcroft@brookes.ac.uk
AN  - WOS:000294642700059
AU  - Foxcroft,
AU  - D.
AU  - R.
AU  - Tsertsvadze,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009307
J2  - Cochrane Database Syst Rev.
KW  - RANDOMIZED CONTROLLED-TRIAL AMERICAN FAMILIES PROGRAM SUBSTANCE-USE OUTCOMES RAISING HEALTHY-CHILDREN GOING PLACES PROGRAM PAST BASE-LINE FOLLOW-UP ADOLESCENT ALCOHOL PROJECT NORTHLAND AFRICAN-AMERICAN Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 817AH Times Cited: 10 Cited Reference Count: 116 Foxcroft, David R. Tsertsvadze, Alexander UK Cochrane Collaboration; NIHR; Oxford Brookes University, UK; NIHR, UK We are grateful to the UK Cochrane Collaboration and the NIHR for providing support to update the 2002 systematic review.Internal sourcesOxford Brookes University, UK.Funding to employ co-reviewerExternal sourcesNIHR, UK.Small grant to update previous review 10 WILEY-BLACKWELL MALDEN COCHRANE DB SYST REV
PY  - 2011
SP  - 70
T2  - Cochrane Database of Systematic Reviews
TI  - Universal multi-component prevention programs for alcohol misuse in young people
UR  - &lt;Go to ISI&gt;://WOS:000294642700059http://onlinelibrary.wiley.com/store/10.1002/14651858.CD009307/asset/CD009307.pdf?v=1&amp;t=ib7v04f7&amp;s=f6e42f03c750fdf2a46381b412bd14fa5405546a
ER  -
TY  - JOUR
AB  - Outcomes of 28 peer-reviewed journal articles published between 1981 and 2007 were evaluated quantitatively to assess the effectiveness of classroom wide interventions for the improvement of social skills. All interventions included in the study were implemented with intact classrooms that included both socially competent children and those with social skills difficulties. In general, the overall effect of school interventions on social behavior was positive but small (effect size = 0.15). Studies were further analyzed according to several variables of interest (e.g., grade of intervention, socioeconomic status, length of intervention, and so on). Several variables moderated the outcome. Particular attention was given to the finding that early interventions were more effective than interventions with older students. These results suggest that resources in classroom-based social skills interventions are best invested in younger students, particularly those in preschool and kindergarten. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Casey, Rita J.: r.casey@wayne.edu Casey, Rita J.: Wayne State University, Department of Psychology, 5057 Woodward, Detroit, MI, US, 48202, r.casey@wayne.edu January, Alicia M.: Wayne State University, Detroit, MI, US Casey, Rita J.: Wayne State University, Detroit, MI, US Paulson, Daniel: Wayne State University, Detroit, MI, US
AN  - 2011-14030-005
AU  - January,
AU  - A.
AU  - M.
AU  - Casey,
AU  - R.
AU  - J.
AU  - Paulson,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Har ikke DOI: https://eric.ed.gov/
DP  - Ovid Technologies
KW  - classroom-wide interventions, social skills *Classrooms *School Based Intervention *Social Skills Curriculum &amp; Programs &amp; Teaching Methods [3530] Human
LA  - English
M3  - Meta Analysis
N1  - Special topic-Assessing and preventing behavior difficulties
PY  - 2011
SP  - 242-256
T2  - School Psychology Review
TI  - A meta-analysis of classroom-wide interventions to build social skills: Do they work?
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2011-14030-005 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=0279-6015&amp;isbn=&amp;volume=40&amp;issue=2&amp;spage=242&amp;pages=242-256&amp;date=2011&amp;title=School+Psychology+Review&amp;atitle=A+meta-analysis+of+classroom-wide+interventions+to+build+social+skills%3A+Do+they+work%3F&amp;aulast=January&amp;pid=%3Cauthor%3EJanuary%2C+Alicia+M%3C%2Fauthor%3E%3CAN%3E2011-14030-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 40
ER  -
TY  - JOUR
AB  - **BACKGROUND** 
Dropping out of high school is associated with numerous detrimental consequences, including low wages, unemployment, incarceration, and poverty. There are a large number of school and community-based prevention and intervention programs for general population and at-risk students, and there are a number of programs designed specifically to encourage school completion among pregnant and parenting teens. No comprehensive systematic reviews have examined these programs&rsquo; overall effectiveness. 

** OBJECTIVES**  
The objectives of this systematic review were to summarize the available evidence on the effects of prevention and intervention programs aimed at primary and secondary students for increasing school completion or reducing school dropout. The primary focus of the meta-analysis was to examine the comparative effectiveness of different programs and program approaches in an effort to identify those with the largest and most reliable effects on school completion and dropout outcomes. We also sought to summarize the effects of programs designed for pregnant and parenting teens. 

**SEARCH STRATEGY**  
A comprehensive and diverse international search strategy was used to locate qualifying studies reported between 1985 and 2010. A wide range of electronic bibliographic databases were searched, along with research registers, other grey literature databases, reference lists of all previous meta-analyses and reviews on the topic, as well as citations in research reports. We also maintained correspondence with researchers in the field of school dropout prevention. 

**SELECTION CRITERIA**  
Studies eligible for inclusion in the review were required to meet several eligibility criteria. First, studies must have involved a school-based or affiliated psychological, educational, or behavioral prevention or intervention program intended to have beneficial effects on students recipients; or, evaluated a community-based program explicitly presented as a dropout prevention or intervention program. Second, studies must have investigated outcomes for interventions directed toward school-aged youth, or those expected to attend pre-k to 12th grade primary and secondary schools or the equivalent. Third, studies must have used experimental or quasi-experimental research designs, including random assignment, non-random assignment with matching, or non-random assignment with statistical controls or sufficient information to permit calculation of pre-treatment effect size group equivalence. Fourth, studies must have reported at least one eligible outcome variable measuring school completion, school dropout, high school graduation, or school attendance. Finally, the date of publication or reporting of the study must have been in 1985 or later. 

**DATA COLLECTION AND ANALYSIS**  
The literature search yielded a total of 23,677 reports, 2,794 which were deemed potentially relevant and retrieved for eligibility determination. Of those, 548 reports describing 167 different studies were included in the final review. Random-effects inverse variance weighted meta-analytic methods were used to synthesize odds ratios for the school dropout outcomes. Meta-regression models were used to examine the effects of program characteristics, methodological characteristics, and participant characteristics on the dropout odds ratios. Funnel plots, regression tests for small sample bias, and trim and fill analyses were used to assess the possibility of publication bias. 

**RESULTS**  
General dropout programs (152 studies; 317 independent samples) and dropout programs for teen parents (15 studies; 51 independent samples) were analyzed in separate meta-analyses. Overall, both general dropout programs and programs specialized for teen parents were effective in reducing school dropout (or increasing school completion). The random effects weighted mean odds ratio for the general programs was 1.72. Using the average dropout rate for control groups of 21.1%, the odds ratio for the general programs translates to a dropout rate of 13%. For the teen parent programs, the mean odds ratio for gradu tion and dropout outcomes was 1.83 and was 1.55 for school enrollment outcomes. The average graduation rate for the young women in comparison groups was 26%. The corresponding graduation rate for young mothers in the intervention programs was 39%. For school enrollment outcomes, the average enrollment rate for the comparison mothers was 33%. The mean odds ratio of 1.55 for these studies translates into an enrollment rate of about 43%. Moderator analyses for the general programs indicated that studies with similar program and comparison groups at baseline and those that provided posttest data adjusted for baseline non-equivalence produced smaller effect sizes. For teen parent programs, moderator analyses found that random and matched designs produced smaller effect sizes than non-random or non-matched designs. Effect sizes were therefore adjusted for methodological characteristics to examine the effects of different program types net of the influence of method. The effects were generally consistent across different types of programs and for different types of participant samples. However, higher levels of implementation quality tended to be associated with larger effects. Analyses provided no strong indication of the presence of publication or small study bias. 

**AUTHOR&rsquo;S CONCLUSIONS**  
Overall, results indicated that most school- and community-based programs were effective in decreasing school dropout. Given the minimal variation in effects across program types, the main conclusion from this review is that dropout prevention and intervention programs, regardless of type, will likely be effective if they are implemented well and are appropriate for the local environment. We recommend that policy makers and practitioners choosing dropout prevention programs consider the cost-effectiveness of programs, and choose those that fit best with local needs as well as implementer abilities and resources.
AU  - Wilson,
AU  - S.
AU  - J.
AU  - Lipsey,
AU  - M.
AU  - Smith,
AU  - E.
AU  - T.
AU  - Huang,
AU  - C.
AU  - H.
AU  - Fry,
AU  - K.
AU  - T.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2011.8
KW  - Students
KW  - Schools
KW  - Dropouts
PY  - 2011
T2  - Campbell Systematic Reviews
TI  - Dropout Prevention and Intervention Programs: Effects on School Completion and Dropout Among School-Aged Children and Youth: A Systematic Review
ER  -
TY  - JOUR
AB  - **Background:** 
Nocturnal enuresis (bedwetting) is a socially disruptive and stressful condition which affects around 15% to 20% of five year olds, and up to 2% of young adults.

**Objectives:** 
To assess the effects of complementary interventions and others such as surgery or diet on nocturnal enuresis in children, and to compare them with other interventions.

**Search methods:** 
We searched PubMed (1950 to June 2010), EMBASE (1980 to June 2010), the Traditional Chinese Medical Literature Analysis and Retrieval System (TCMLARS) (1984 to June 2010), Chinese Biomedical Literature Database (CBM) (1975 to June 2010), China National Knowledge Infrastructure (CNKI) (1979 to June 2010), VIP database (1989 to June 2010), and the reference lists of relevant articles, all last searched 26 June 2010. No language restriction was used.


**Selection criteria:** 
All randomised or quasi-randomised trials of complementary and other miscellaneous interventions for nocturnal enuresis in children were included except those focused solely on daytime wetting. Comparison interventions could include no treatment, placebo or sham treatment, alarms, simple behavioural treatment, desmopressin, imipramine and miscellaneous other drugs and interventions.

**Data collection and analysis:** 
Two reviewers independently assessed the quality of the eligible trials, and extracted data.

**Main results:** 
In 24 randomised controlled trials, 2334 children were studied, of whom 1283 received a complementary intervention. The quality of the trials was poor: 5 trials were quasi-randomised, 5 showed differences at baseline and 17 lacked follow up data.The outcome was better after hypnosis than imipramine in one trial (relative risk (RR) for failure or relapse after stopping treatment 0.42, 95% confidence interval (CI) 0.23 to 0.78). Psychotherapy appeared to be better in terms of fewer children failing or relapsing than both alarm (RR 0.28, 95% CI 0.09 to 0.85) and rewards (RR 0.29, 95%CI 0.09 to 0.90) but this depended on data from only one trial. Medicinal herbs had better results than desmopressin in one trial (RR for failure or relapse after stopping treatment 0.35, 95% CI 0.14 to 0.85). Acupuncture had better results than sham control acupuncture (RR for failure or relapse after stopping treatment 0.67, 95% CI 0.48 to 0.94) in a further trial. Active chiropractic adjustment had better results than sham adjustment (RR for failure to improve 0.76, 95% CI 0.60 to 0.95). However, each of these findings came from small single trials, and must be verified in further trials. The findings for diet and faradization were unreliable, and there were no trials including homeopathy or surgery.

**Authors&#039; conclusions:** 
There was weak evidence to support the use of hypnosis, psychotherapy, acupuncture, chiropractic and medicinal herbs but it was provided in each case by single small trials, some of dubious methodological rigour. Robust randomised trials are required with efficacy, cost-effectiveness and adverse effects clearly reported.
AN  - CD005230
AU  - Huang,
AU  - T.
AU  - Shu,
AU  - X.
AU  - Huang,
AU  - Y.
AU  - S.
AU  - Cheuk,
AU  - D.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd005230
KW  - Psychotherapy
KW  - Acupuncture Therapy
KW  - Complementary Therapies [methods]
KW  - Counseling
KW  - Deamino Arginine Vasopressin [therapeutic use]
KW  - Electric Stimulation Therapy
KW  - Homeopathy
KW  - Hypnosis
KW  - Manipulation, Chiropractic
KW  - Nocturnal Enuresis [therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Renal Agents [therapeutic use]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Incont
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Complementary and miscellaneous interventions for nocturnal enuresis in children
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005230.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005230.pub2/asset/CD005230.pdf?v=1&amp;t=iw7j6u34&amp;s=251b7da4ebce2654d69e391c2b3a02680b6dad06
ER  -
TY  - JOUR
AB  - Joint attention is a skill that involves coordinating the attention of at least two individuals towards an object or event. 

Although it is seen as a critical skill in early child development, it is frequently absent in children with autism and has been linked to poorer language outcomes for those children. As a result, multiple interventions have been developed to teach children with autism to respond to, and initiate, bids for joint attention. 

These interventions, however, differ widely both in terms of procedures used and in whether they focus on teaching children to respond to, or initiate, bids for joint attention. 

This literature review was conducted to document research gaps and intervention similarities between joint attention intervention studies for children with autism. 

The specific intent of this review was to determine whether researchers teach responding and initiating separately or sequentially, describe the extent to which procedures differ among studies, and identify whether social or non-social consequences are used during joint attention training. Implications for the treatment of joint attention deficits are discussed and recommendations to both researchers and practitioners are provided. 

(C) 2011 Elsevier Ltd. All rights reserved.
AD  - [Meindl, James N.; Cannella-Malone, Helen I.] Ohio State Univ, Coll Educ &amp; Human Ecol, Sch Phys Act &amp; Educ Serv, Columbus, OH 43210 USA. Meindl, JN (reprint author), Ohio State Univ, Sch PAES, PAES Bldg,17th Ave, Columbus, OH 43201 USA. meindl.2@buckeyemail.osu.edu
AN  - WOS:000293310600004
AU  - Meindl,
AU  - J.
AU  - N.
AU  - Cannella-Malone,
AU  - H.
AU  - I.
DA  - Sep-Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.ridd.2011.02.013
J2  - Res. Dev. Disabil.
KW  - Joint attention Autism Initiating joint attention Responding to joint attention Literature review SINGLE-SUBJECT RESEARCH YOUNG-CHILDREN QUANTITATIVE SYNTHESIS TEACHING-CHILDREN PRETEND PLAY LANGUAGE INTERVENTION IMITATION SKILLS BEHAVIORS Education, Sp
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 799UC Times Cited: 10 Cited Reference Count: 38 Meindl, James N. Cannella-Malone, Helen I. Malone, Helen/E-3150-2012 10 PERGAMON-ELSEVIER SCIENCE LTD OXFORD RES DEV DISABIL
PY  - 2011
SP  - 1441-1454
T2  - Research in Developmental Disabilities
TI  - Initiating and responding to joint attention bids in children with autism: A review of the literature
UR  - &lt;Go to ISI&gt;://WOS:000293310600004http://ac.els-cdn.com/S0891422211000886/1-s2.0-S0891422211000886-main.pdf?_tid=d3e0ba9a-167b-11e5-a6bb-00000aacb35e&amp;acdnat=1434715859_31d3b7785016ee7c593080425047dc9c
VL  - 32
ER  -
TY  - GEN
AB  - **Background:* 
Autism spectrum disorders (ASD) are characterized by impairment in social interaction, impairment in communication and lack of flexibility of thought and behavior. Acupuncture, which involves the use of needles or pressure to specific points on the body, is used widely in Traditional Chinese Medicine and increasingly within a western medical paradigm. It has sometimes been used as a treatment aimed at improving ASD symptoms and outcomes, but its clinical effectiveness and safety has not been rigorously reviewed.

**Objectives:** 
To determine the effectiveness of acupuncture for people with ASD in improving core autistic features, as well as communication, cognition, overall functioning and quality of life, and to establish if it has any adverse effects.

**Search methods:** 
We searched the following databases on 30 September 2010: CENTRAL (The Cochrane Library, 2010, Issue 3), MEDLINE (1950 to September 2010 Week 2), EMBASE (1980 to 2010 Week 38), PsycINFO, CINAHL, China Journal Full-text Database, China Master Theses Full-text Database, China Doctor Dissertation Full-text Database, China Proceedings of Conference Database, Index to Taiwan Periodical Literature System, metaRegister of Controlled Trials and the Chinese Clinical Trials Registry. We also searched AMED (26 February 2009) and Dissertation Abstracts International (3 March 2009), but these were no longer available to the authors or editorial base at the date of the most recent search. TCMLARS (Traditional Chinese Medical Literature Analysis and Retrieval System) was last searched on 3 March 2009.

**Selection criteria:** 
We included randomized and quasi-randomized controlled trials. We included studies comparing an acupuncture group with at least one control group that used no treatment, placebo or sham acupuncture treatment in people with ASD. We excluded trials that compared different forms of acupuncture or compared acupuncture with another treatment.

**Data collection and analysis:** 
Two review authors independently extracted trial data and assessed the risk of bias in the trials. We used relative risk (RR) for dichotomous data and mean difference (MD) for continuous data.

**Main results:**
We included 10 trials that involved 390 children with ASD. The age range was three to 18 years and the treatment duration ranged from four weeks to nine months. The studies were carried out in Hong Kong, mainland China and Egypt.Two trials compared needle acupuncture with sham acupuncture and found no difference in the primary outcome of core autistic features (RFRLRS total score: MD 0.09; 95% CI -0.03 to 0.21, P = 0.16), although results suggested needle acupuncture might be associated with improvement in some aspects of the secondary outcomes of communication and linguistic ability, cognitive function and global functioning.Six trials compared needle acupuncture plus conventional treatment with conventional treatment alone. The trials used different primary outcome measures and most could not demonstrate effectiveness of acupuncture in improving core autistic features in general, though one trial reported patients in the acupuncture group were more likely to have improvement on the Autism Behavior Checklist (RR 1.53; 95% CI 1.09 to 2.16, P = 0.02) and had slightly better post-treatment total scores (MD -5.53; 95% CI -10.76 to -0.31, P = 0.04). There was no evidence that acupuncture was effective for the secondary outcome of communication and linguistic ability, though there seemed to be some benefit for the secondary outcomes of cognitive function and global functioning.Two trials compared acupressure plus conventional treatment with conventional treatment alone and did not report on the primary outcome. Individual study results suggested there may be some benefit from acupressure for certain aspects of the secondary outcomes of communication and linguistic ability, cognitive function and global functioning.Four trials reported some adverse effects, though there was little quantitative information, and at times both intervention and control groups experienced them. Adverse effects noted included bleeding, crying due to fear or pain, irritability, sleep disturbance and increased hyperactivity. None of the trials reported on quality of life.There are a number of problems with the evidence base: the trials were few in number and included only children; six of the trials were at high risk of bias; they were heterogeneous in terms of participants and intervention; they were of short duration and follow-up; they reported inconsistent and imprecise results, and, due to carrying out large numbers of analyses, they were at risk of false positivity.

**Authors&#039; conclusions:** 
Current evidence does not support the use of acupuncture for treatment of ASD. There is no conclusive evidence that acupuncture is effective for treatment of ASD in children and no RCTs have been carried out with adults. Further high quality trials of larger size and longer follow-up are needed.
AN  - CD007849
AU  - Cheuk,
AU  - D.
AU  - K.
AU  - Wong,
AU  - V.
AU  - Chen,
AU  - W.
AU  - X.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007849.pub2
KW  - Acupuncture Therapy [methods]
KW  - Child Development Disorders, Pervasive [therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Outcome
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Behav
L1  - internal-pdf://0544913483/Cheuk-2011-Acupuncture for autism spectrum dis.pdf
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Acupuncture for autism spectrum disorders (ASD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007849.pub2/abstract
UR  - http://onlinelibrary.wiley.com/store/10.1002/14651858.CD007849.pub2/asset/CD007849.pdf?v=1&amp;t=iw7imh3s&amp;s=e80654d2bbc4b6bbef23c9cfbe8bc63dcf8ad6d0
ER  -
TY  - JOUR
AB  - Anxiety disorders are the most frequent psychiatric disorders in children and adolescents and have adverse effects on their psychosocial functioning. An increasing number of studies are aimed at its prevention. 

This meta-analysis included 65 studies on anxiety prevention. We found small but significant effects on anxiety at posttest (symptoms: g = .22, diagnosis: g = .23; SD units) and follow-up (symptoms: g = .19, diagnosis: g = .32). Intervention effects at posttest varied by type of prevention: Indicated/selective prevention programs showed lager effect sizes than universal programs. 

At follow-up, smaller effects were found in samples with higher percentages of girls and stronger effect size for programs focusing primarily on anxiety prevention. 

We conclude: Anxiety prevention programs produce effects size of practical relevance. More efforts are needed for assessing the long-term program effects on the risk for developing anxiety disorders and for improving long-term prevention effects on girls. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - Teubert, Daniela: teubertd@staff.uni-marburg.de; Pinquart, Martin: pinquart@staff.uni-marburg.de Teubert, Daniela: Philipps University Marburg, Department of Educational and Developmental Psychology, Gutenbergstrasse 18, Marburg, Germany, 35032, teubertd@staff.uni-marburg.de Teubert, Daniela: Philipps University Marburg, Department of Educational and Developmental Psychology, Marburg, Germany Pinquart, Martin: Philipps University Marburg, Department of Educational and Developmental Psychology, Marburg, Germany
AN  - 2011-23975-010
AU  - Teubert,
AU  - D.
AU  - Pinquart,
AU  - M.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.janxdis.2011.07.001
DP  - Ovid Technologies
KW  - anxiety symptoms, psychiatric disorders, psychosocial functioning, anxiety prevention *Anxiety *Anxiety Disorders *Psychosocial Factors *Symptoms Prevention Neuroses &amp; Anxiety Disorders [3215] Human
LA  - English
M3  - Meta Analysis
PY  - 2011
SP  - 1046-1059
T2  - Journal of Anxiety Disorders
TI  - A meta-analytic review on the prevention of symptoms of anxiety in children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2011-23975-010 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.janxdis.2011.07.001&amp;issn=0887-6185&amp;isbn=&amp;volume=25&amp;issue=8&amp;spage=1046&amp;pages=1046-1059&amp;date=2011&amp;title=Journal+of+Anxiety+Disorders&amp;atitle=A+meta-analytic+review+on+the+prevention+of+symptoms+of+anxiety+in+children+and+adolescents.&amp;aulast=Teubert&amp;pid=%3Cauthor%3ETeubert%2C+Daniela%3C%2Fauthor%3E%3CAN%3E2011-23975-010%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 25
ER  -
TY  - JOUR
AB  - **Background **
Alcoholmisuse in young people is a cause of concern for health services, policy makers, prevention workers, and criminal justice system, youth workers, teachers, and parents. 

**Objectives **
To systematically review evidence on the effectiveness of universal family-based prevention programs in preventing alcohol misuse in school-aged children up to 18 years of age. To update a part of a previously published Cochrane systematic review. 

**Search strategy **
Relevant evidence ( up to 2002) was selected from the previous Cochrane review. Later studies, to July 2010, were identified from MEDLINE, Cochrane Central Register of Controlled Trials, EMBASE, Project CORK, and PsycINFO. 

**Selection criteria **
Randomized trials evaluating universal family-based prevention programs and reporting outcomes for alcohol use in students 18 years of age or younger were included. Two reviewers screened titles/abstracts and full text of identified records. 

**Data collection and analysis**
Two reviewers extracted relevant data independently using an a priori defined extraction form. Risk of bias was assessed. 

**Main results **
12 parallel-group trials were included. The reporting quality of trials was poor, only 20% of them reporting adequate method of randomisation and program allocation concealment. Incomplete data was adequately addressed in about half of the trials and this information was unclear for about 30% of the trials. Due to extensive heterogeneity across interventions, populations, and outcomes, the results were summarized only qualitatively. 9 of the 12 trials showed some evidence of effectiveness compared to a control or other intervention group, with persistence of effects over the medium and longer-term. Four of these effective interventions were gender-specific, focusing on young females. One study with a small sample size showed positive effects that were not statistically significant, and two studies with larger sample sizes reported no significant effects of the family-based intervention for reducing alcohol misuse. 

**Authors&#039; conclusions **
In conclusion, in this Cochrane systematic review we found that that the effects of family-based prevention interventions are small but generally consistent and also persistent into the medium- to longer-term.
AD  - [Foxcroft, David R.] Oxford Brookes Univ, Sch Hlth &amp; Social Care, Oxford OX3 0FL, England. [Tsertsvadze, Alexander] Univ Ottawa Evidence Based Practice Ctr, Clin Epidemiol Methods Ctr, Ottawa Hosp Res Inst, Ottawa, ON, Canada. Foxcroft, DR (reprint author), Oxford Brookes Univ, Sch Hlth &amp; Social Care, Marston Rd,Jack Straws Lane, Oxford OX3 0FL, England. david.foxcroft@brookes.ac.uk
AN  - WOS:000294642700060
AU  - Foxcroft,
AU  - D.
AU  - R.
AU  - Tsertsvadze,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009308
J2  - Cochrane Database Syst Rev.
KW  - RANDOMIZED CONTROLLED-TRIAL ADOLESCENT SUBSTANCE USE RAISING HEALTHY-CHILDREN AFRICAN-AMERICAN FOLLOW-UP COLLEGE-STUDENTS DRUG-ABUSE HEAVY DRINKING USE DISORDERS USE OUTCOMES Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 817AH Times Cited: 14 Cited Reference Count: 112 Foxcroft, David R. Tsertsvadze, Alexander UK Cochrane Collaboration; NIHR We are grateful to the UK Cochrane Collaboration and the NIHR for providing support to update the 2002 systematic review. 14 WILEY-BLACKWELL MALDEN COCHRANE DB SYST REV
PY  - 2011
SP  - 34
T2  - Cochrane Database of Systematic Reviews
TI  - Universal family-based prevention programs for alcohol misuse in young people
UR  - &lt;Go to ISI&gt;://WOS:000294642700060http://onlinelibrary.wiley.com/store/10.1002/14651858.CD009308/asset/CD009308.pdf?v=1&amp;t=ib7tds7f&amp;s=0b8567c0e5482d95766352f8e2518b3a1e93367f
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To review data on efficacy and safety of second-generation antipsychotics (SGAs) in children and adolescents with psychotic and bipolar spectrum disorders. 

**METHODS:** 
Medline/PubMed/Google Scholar search for studies comparing efficacy and/or tolerability: (i) between two or more SGAs; (ii) between SGAs and placebo; and (iii) between at least one SGA and one first-generation antipsychotic (FGA). The review focused on three major side-effect clusters: 1. body weight, body mass index, and cardiometabolic parameters, 2. prolactin levels, and 3. neuromotor side effects. 

**RESULTS:**
In total, 34 studies with 2719 children and adolescents were included. Studies lasted between 3 weeks and 12 months, with most studies (79.4%) lasting 3 months or less. Nine studies (n=788) were conducted in patients with schizophrenia, 6 (n=719) in subjects with bipolar disorder, and 19 (n=1212) in a mixed population. Data on efficacy showed that, except for clozapine being superior for refractory schizophrenia, there were no significant differences between SGAs. By contrast, safety assessments showed relevant differences between SGAs. Mean weight gain ranged from 3.8 kg to 16.2 kg in patients treated with olanzapine (n=353), from 0.9 kg to 9.5 kg in subjects receiving clozapine (n=97), from 1.9 kg to 7.2 kg in those on risperidone (n=571), from 2.3 kg to 6.1 kg among patients taking quetiapine (n=133), and from 0 kg to 4.4 kg in those treated with aripiprazole (n=451). Prolactin levels increased the most in subjects on risperidone (mean change ranging from 8.3 ng/mL to 49.6 ng/mL), followed by olanzapine (-1.5 ng/mL to +13.7 ng/mL). Treatment with aripiprazole was associated with decreased prolactin levels, while clozapine and quetiapine were found to be mostly neutral. With respect to neuromotor side effects, SGAs were associated with less parkinsonism and akathisia than FGAs. Most of the studies comparing neuromotor side effects between SGAs found no significant differences. 

**CONCLUSIONS: **
SGAs do not behave as a homogeneous group in children and adolescents with psychotic and mood disorders. Except for clozapine, the heterogeneity within the SGA group is mainly due to differences in the rates and severity of adverse events, especially regarding weight gain as a proxy for the risk of cardiometabolic disturbances.

Copyright Published by Elsevier B.V.
AD  - Fraguas,David. Servicio de Salud Mental, Complejo Hospitalario Universitario de Albacete, Centro de Investigacion Biomedica en Red de Salud Mental, CIBERSAM, Albacete, Spain.
AN  - 20702068
AU  - Fraguas,
AU  - D.
AU  - Correll,
AU  - C.
AU  - U.
AU  - Merchan-Naranjo,
AU  - J.
AU  - Rapado-Castro,
AU  - M.
AU  - Parellada,
AU  - M.
AU  - Moreno,
AU  - C.
AU  - Arango,
AU  - C.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.euroneuro.2010.07.002
DP  - Ovid Technologies
J2  - Eur Neuropsychopharmacol
KW  - Adolescent *Antipsychotic Agents/ae [Adverse Effects] *Antipsychotic Agents/tu [Therapeutic Use] *Bipolar Disorder/dt [Drug Therapy] Child Dose-Response Relationship, Drug Drug Administration Schedule Female Humans Male Placebos *Psychotic Disorders/dt
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Fraguas, David Correll, Christoph U Merchan-Naranjo, Jessica Rapado-Castro, Marta Parellada, Mara Moreno, Carmen Arango, Celso
PY  - 2011
SP  - 621-45
T2  - European Neuropsychopharmacology
TI  - Efficacy and safety of second-generation antipsychotics in children and adolescents with psychotic and bipolar spectrum disorders: comprehensive review of prospective head-to-head and placebo-controlled comparisons
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=20702068 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20702068&amp;id=doi:10.1016%2Fj.euroneuro.2010.07.002&amp;issn=0924-977X&amp;isbn=&amp;volume=21&amp;issue=8&amp;spage=621&amp;pages=621-45&amp;date=2011&amp;title=European+Neuropsychopharmacology&amp;atitle=Efficacy+and+safety+of+second-generation+antipsychotics+in+children+and+adolescents+with+psychotic+and+bipolar+spectrum+disorders%3A+comprehensive+review+of+prospective+head-to-head+and+placebo-controlled+comparisons.&amp;aulast=Fraguas&amp;pid=%3Cauthor%3EFraguas+D%3C%2Fauthor%3E%3CAN%3E20702068%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0924977X10001586/1-s2.0-S0924977X10001586-main.pdf?_tid=d626f622-18db-11e5-bcea-00000aacb35e&amp;acdnat=1434976997_0e688d95a404a2466d3d93267a925f51
VL  - 21
ER  -
TY  - JOUR
AB  - School recess is an opportunity to include students with autism spectrum disorders (ASD) with their typically developing peers and is a setting in which instruction can occur. However, the educational opportunities for children with ASD within recess are often overlooked and recess time is being reduced or eliminated in the United States. 

This review involved a systematic search and analysis of 15 studies that utilized recess to implement academic, social, or behavioral interventions for students with ASD. 
Each identified study that met predetermined inclusion criteria was analyzed and summarized in terms of: (a) participant characteristics, (b) intervention procedures, (c) dependent variables, and (d) intervention outcomes. 

This review has three main aims: (a) to evaluate and synthesize the evidence-base, (b) to inform and guide teachers interested in utilizing recess time for educational purposes, and (c) to stimulate and guide future research in this area. 

Results demonstrate that recess time can indeed be used to teach target behaviors to students with ASD. 

(C) 2011 Elsevier Ltd. All rights reserved.
AD  - [Lang, Russell] Texas State Univ San Marcos, Dept Curriculum &amp; Instruct, Clin Autism Res Evaluat &amp; Support, San Marcos, TX 78666 USA. [Kuriakose, Sarah] Univ Calif Santa Barbara, Santa Barbara, CA 93106 USA. [Lyons, Gregory] Univ Wisconsin, Madison, WI 53706 USA. [Mulloy, Austin; O&#039;Reilly, Mark] Univ Texas Austin, Meadows Ctr Prevent Educ Risk, Austin, TX 78712 USA. [Lancioni, Giulio] Univ Bari, I-70121 Bari, Italy. Lang, R (reprint author), Texas State Univ San Marcos, Dept Curriculum &amp; Instruct, Clin Autism Res Evaluat &amp; Support, 601 Univ Dr, San Marcos, TX 78666 USA. russlang@txstate.edu
AN  - WOS:000292235600003
AU  - Lang,
AU  - R.
AU  - Kuriakose,
AU  - S.
AU  - Lyons,
AU  - G.
AU  - Mulloy,
AU  - A.
AU  - Boutot,
AU  - A.
AU  - Britt,
AU  - C.
AU  - Caruthers,
AU  - S.
AU  - Ortega,
AU  - L.
AU  - O&#039;
AU  - Reilly,
AU  - M.
AU  - Lancioni,
AU  - G.
DA  - Oct-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.rasd.2011.02.012
J2  - Res. Autism Spectr. Disord.
KW  - Autism Recess Play Intervention Review Playground HIGH-FUNCTIONING AUTISM SOCIAL-SKILLS CHALLENGING BEHAVIOR YOUNG-CHILDREN SPECIAL NEEDS INTERVENTION PLAY PEERS INITIATIONS PERCENTAGE Education, Special Psychology, Developmental Psychiatry Rehabilitati
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 785NL Times Cited: 6 Cited Reference Count: 53 Lang, Russell Kuriakose, Sarah Lyons, Gregory Mulloy, Austin Boutot, Amanda Britt, Courtney Caruthers, Stephanie Ortega, Lilia O&#039;Reilly, Mark Lancioni, Giulio Moriana, Juan Antonio/B-4268-2008 6 ELSEVIER SCI LTD OXFORD RES AUTISM SPECT DIS
PY  - 2011
SP  - 1296-1305
T2  - Research in Autism Spectrum Disorders
TI  - Use of school recess time in the education and treatment of children with autism spectrum disorders: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000292235600003http://ac.els-cdn.com/S1750946711000560/1-s2.0-S1750946711000560-main.pdf?_tid=8ef47f98-167b-11e5-99d7-00000aacb361&amp;acdnat=1434715744_4cbe646e81a018619239b2536ec45d83
VL  - 5
ER  -
TY  - JOUR
AB  - The purpose of this review is to provide a systematic analysis of studies involving the use of computer-based interventions (CBI) to teach communication skills to children with autism spectrum disorders (ASD). 

This review evaluates intervention outcomes, appraises the certainty of evidence, and describes software and system requirements for each included study. 

This review has three main aims: (a) to evaluate the evidence-base regarding CBI, (b) to inform and guide practitioners interested in using CBI, and (c) to stimulate and guide future research aimed at improving the efficiency and effectiveness of CBI in communication for individuals with ASD. 

Results suggest that CBI should not yet be considered a researched-based approach to teaching communication skills to individuals with ASD. However, CBI does seem a promising practice that warrants future research. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Ramdoss, Sathiyaprakash: sathiya.ramdoss@mail.utexas.edu Ramdoss, Sathiyaprakash: Department of Special Education, University of Texas at Austin, 1 University Station D5300, Austin, TX, US, 78712, sathiya.ramdoss@mail.utexas.edu Ramdoss, Sathiyaprakash: Meadows Center for the Prevention of Educational Risk, University of Texas at Austin, Austin, TX, US Lang, Russell: Texas State University, San Marcos, TX, US Mulloy, Austin: Meadows Center for the Prevention of Educational Risk, University of Texas at Austin, Austin, TX, US Franco, Jessica: Autism Community Network, San Antonio, TX, US O&#039;Reilly, Mark: Meadows Center for the Prevention of Educational Risk, University of Texas at Austin, Austin, TX, US Didden, Robert: Radboud University Nijmegen, Nijmegen, Netherlands Lancioni, Giulio: University of Bari, Bari, Italy
AN  - 2011-05119-006
AU  - Ramdoss,
AU  - S.
AU  - Lang,
AU  - R.
AU  - Mulloy,
AU  - A.
AU  - Franco,
AU  - J.
AU  - O&#039;Reilly,
AU  - M.
AU  - Didden,
AU  - R.
AU  - Lancioni,
AU  - G.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10864-010-9112-7
DP  - Ovid Technologies
KW  - autism, autism spectrum disorders, computer-based intervention, computer-assisted intervention, communication skills training, intervention outcomes, children *Autism *Communication Skills Training *Computer Assisted Instruction *Pervasive Developmental
LA  - English
M3  - Literature Review; Systematic Review
N1  - Special Issue: Evaluating assistive technology in the education of persons with severe disabilities
PY  - 2011
SP  - 55-76
T2  - Journal of Behavioral Education
TI  - Use of computer-based interventions to teach communication skills to children with autism spectrum disorders: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2011-05119-006 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10864-010-9112-7&amp;issn=1053-0819&amp;isbn=&amp;volume=20&amp;issue=1&amp;spage=55&amp;pages=55-76&amp;date=2011&amp;title=Journal+of+Behavioral+Education&amp;atitle=Use+of+computer-based+interventions+to+teach+communication+skills+to+children+with+autism+spectrum+disorders%3A+A+systematic+review.&amp;aulast=Ramdoss&amp;pid=%3Cauthor%3ERamdoss%2C+Sathiyaprakash%3C%2Fauthor%3E%3CAN%3E2011-05119-006%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://download.springer.com/static/pdf/549/art%253A10.1007%252Fs10864-010-9112-7.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10864-010-9112-7&amp;token2=exp=1434702968~acl=%2Fstatic%2Fpdf%2F549%2Fart%25253A10.1007%25252Fs10864-010-9112-7.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10864-010-9112-7*~hmac=821bc795a18fac2d3344061bd64fac0892229c78c6438cf7a3d8009890b89ad1
VL  - 20
ER  -
TY  - JOUR
AB  - **Background:**
Auditory integration therapy was developed as a technique for improving abnormal sound sensitivity in individuals with behavioural disorders including autism spectrum disorders. Other sound therapies bearing similarities to auditory integration therapy include the Tomatis Method and Samonas Sound Therapy.

**Objectives:** 
To determine the effectiveness of auditory integration therapy or other methods of sound therapy in individuals with autism spectrum disorders.Search methods: For this update, we searched the following databases in September 2010: CENTRAL (2010, Issue 2), MEDLINE (1950 to September week 2, 2010), EMBASE (1980 to Week 38, 2010), CINAHL (1937 to current), PsycINFO (1887 to current), ERIC (1966 to current), LILACS (September 2010) and the reference lists of published papers. One new study was found for inclusion.

**Selection criteria:** 
Randomised controlled trials involving adults or children with autism spectrum disorders. Treatment was auditory integration therapy or other sound therapies involving listening to music modified by filtering and modulation. Control groups could involve no treatment, a waiting list, usual therapy or a placebo equivalent. The outcomes were changes in core and associated features of autism spectrum disorders, auditory processing, quality of life and adverse events.

**Data collection and analysis:** 
Two independent review authors performed data extraction. All outcome data in the included papers were continuous. We calculated point estimates and standard errors from t-test scores and post-intervention means. Meta-analysis was inappropriate for the available data.

**Main results:** 
We identified six randomised comtrolled trials of auditory integration therapy and one of Tomatis therapy, involving a total of 182 individuals aged three to 39 years. Two were cross-over trials. Five trials had fewer than 20 participants. Allocation concealment was inadequate for all studies. Twenty different outcome measures were used and only two outcomes were used by three or more studies. Meta-analysis was not possible due to very high heterogeneity or the presentation of data in unusable forms. Three studies (Bettison 1996; Zollweg 1997; Mudford 2000) did not demonstrate any benefit of auditory integration therapy over control conditions. Three studies (Veale 1993; Rimland 1995; Edelson 1999) reported improvements at three months for the auditory integration therapy group based on the Aberrant Behaviour Checklist, but they used a total score rather than subgroup scores, which is of questionable validity, and Veale&#039;s results did not reach statistical significance. Rimland 1995 also reported improvements at three months in the auditory integration therapy group for the Aberrant Behaviour Checklist subgroup scores. The study addressing Tomatis therapy (Corbett 2008) described an improvement in language with no difference between treatment and control conditions and did not report on the behavioural outcomes that were used in the auditory integration therapy trials.

**Authors&#039; conclusions:** 
There is no evidence that auditory integration therapy or other sound therapies are effective as treatments for autism spectrum disorders. As synthesis of existing data has been limited by the disparate outcome measures used between studies, there is not sufficient evidence to prove that this treatment is not effective. However, of the seven studies including 182 participants that have been reported to date, only two (with an author in common), involving a total of 35 participants, report statistically significant improvements in the auditory intergration therapy group and for only two outcome measures (Aberrant Behaviour Checklist and Fisher&#039;s Auditory Problems Checklist). As such, there is no evidence to support the use of auditory integration therapy at this time.
AN  - CD003681
AU  - Sinha,
AU  - Y.
AU  - Silove,
AU  - N.
AU  - Hayen,
AU  - A.
AU  - Williams,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003681.pub3
KW  - Acoustic Stimulation [methods]
KW  - Autistic Disorder [therapy]
KW  - Music Therapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Young Adult[checkword]
KW  - Behav
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Auditory integration training and other sound therapies for autism spectrum disorders (ASD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003681.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003681.pub3/asset/CD003681.pdf?v=1&amp;t=iw7ivsmo&amp;s=3ec3b82912952bf18a3ab3b509f31425cd44436a
ER  -
TY  - JOUR
AB  - **Background:**
Anxiety during pregnancy is a common problem. Anxiety and stress could have consequences on the course of the pregnancy and the later development of the child. Anxiety responds well to treatments such as cognitive behavioral therapy and/or medication. Non-pharmacological interventions such as mind-body interventions, known to decrease anxiety in several clinical situations, might be offered for treating and preventing anxiety during pregnancy.

**Objectives:** 
To assess the benefits of mind-body interventions during pregnancy in preventing or treating women&#039;s anxiety and&nbsp;in influencing perinatal outcomes.

**Search methods:**
We searched the Cochrane Pregnancy and Childbirth Group?s Trials Register (30 November 2010), MEDLINE (1950 to 30 November 2010), EMBASE (1974 to 30 November 2010), the National Center for Complementary and Alternative Medicine (NCCAM) (1 December 2010), ClinicalTrials.gov (December 2010) and Current Controlled Trials (1 December 2010), searched the reference lists of selected studies and contacted professionals and authors in the field.

**Selection criteria:**
Randomized controlled trials, involving pregnant women of any age at any time from conception to one month after birth, comparing mind-body interventions with a control group. Mind-body interventions include: autogenic training, biofeedback, hypnotherapy, imagery, meditation, prayer, auto-suggestion, tai-chi and yoga. Control group includes: standard care, other pharmacological or non-pharmacological interventions, other types of mind-body interventions or no treatment at all.

**Data collection and analysis:**
Three review authors independently assessed trials for inclusion all assessed risk of bias for each included study. We extracted data independently using an agreed form and checked it for accuracy.

**Main results:** 
We included eight trials (556 participants), evaluating hypnotherapy (one trial), imagery (five trials), autogenic training (one trial) and yoga (one trial). Due to the small number of studies per intervention and to the diversity of outcome measurements, we performed no meta-analysis, and have reported results individually for each study. Compared with usual care, in one study (133 women), imagery may have a positive effect on anxiety during labor decreasing anxiety at the early and middle stages of labor (MD -1.46; 95% CI -2.43 to -0.49; one study, 133 women) and (MD -1.24; 95% CI -2.18 to -0.30). Another study showed that imagery had a positive effect on anxiety and depression in the immediate postpartum period. Autogenic training might be effective for decreasing women&#039;s anxiety before delivering.

**Authors&#039; conclusions:**
Mind-body interventions might benefit women?s anxiety during pregnancy. Based on individual studies, there is some but no strong evidence for the effectiveness of mind-body interventions for the management of anxiety during pregnancy. The main limitations of the studies were the lack of blinding and insufficient details on the methods used for randomization.
AN  - CD007559
AU  - Marc,
AU  - I.
AU  - Toureche,
AU  - N.
AU  - Ernst,
AU  - E.
AU  - Hodnett,
AU  - E.
AU  - D.
AU  - Blanchet,
AU  - C.
AU  - Dodin,
AU  - S.
AU  - Njoya,
AU  - M.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007559
KW  - Anxiety [prevention &amp; control]
KW  - Autogenic Training
KW  - Hypnosis [methods]
KW  - Imagery (Psychotherapy) [methods]
KW  - Mind-Body Therapies [methods]
KW  - Pregnancy Complications [prevention &amp; control] [psychology] [therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Yoga
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Pregnancy[checkword]
KW  - Preg
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Mind-body interventions during pregnancy for preventing or treating women&#039;s anxiety
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007559.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007559.pub2/asset/CD007559.pdf?v=1&amp;t=iw7k6ivk&amp;s=7a30a246c45f8e75b8c13ef8af5609c6e7f8d6d9
ER  -
TY  - JOUR
AB  - This review examines the effects of teachers‟ universal classroom management practices in reducing disruptive, aggressive, and inappropriate behaviors. The specific research questions addressed are: Do teacher‟s universal classroom management practices reduce problem behavior in classrooms with students in kindergarten through 12th grade? What components make up the most effective and efficient classroom management programs? Do differences in effectiveness exist between grade levels? Do differences in classroom management components exist between grade levels? Does treatment fidelity affect the outcomes observed? These questions were addressed through a systematic review of the classroom management literature and a meta-analysis of the effects of classroom management on disruptive or aggressive student behavior. 

Twelve studies of universal classroom management programs were included in the review. The classroom-level mean effect size for the 12 programs was positive and statistically significant (d=.80 with an ICC=.05; =.71 with an ICC=.10; &lt;.05). Note that cluster adjustments were required due to differences in reporting measures between classroom level outcomes and individual student level outcomes. The resulting effect sizes index classroom-level differences and cannot be compared to the typical student-level effect sizes commonly reported in the literature. Due to a lack of power to detect heterogeneity and lack of information reported in the studies reviewed, only the first research question could be addressed. Teacher&#039;s classroom management practices have a significant, positive effect on decreasing problem behavior in the classroom. Students in the treatment classrooms in all 12 studies located for the review showed less disruptive, inappropriate, and aggressive behavior in the classroom compared to untreated students in the control classrooms. The overall mean classroom effect size of either .80 or .71 indicates a positive effect that significantly impacts the classroom environment. To put our classroom-level mean effect sizes into a comparable format with the more typical effect sizes, we back-transformed our mean effect sizes using the original adjustment formulas (Hedges, 2007). Thus, the classroom-level mean effect sizes of .80 and .71 are roughly comparable to student level effect sizes of .18 and .22 for ICC=.05 and ICC=.10, respectively. Teachers who use effective classroom management can expect to experience improvements in student behavior and improvements that establish the context for effective instructional practices to occur.
AU  - Oliver,
AU  - R.
AU  - Reschly,
AU  - D.
AU  - Wehby,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2011.4
KW  - Student behaviour
KW  - Student teacher relationship
KW  - Classroom techniques
KW  - School discipline
KW  - Teacher authority
PY  - 2011
T2  - Campbell Systematic Reviews
TI  - The Effects of Teachers Classroom Management Practices on Disruptive, or Aggressive Student Behavior: A Systematic Review
ER  -
TY  - JOUR
AB  - **Background:
Parenting programmes are a potentially important means of supporting teenage parents and improving outcomes for their children, and parenting support is a priority across most Western countries. This review updates the previous version published in 2001.

**Objectives:** 
To examine the effectiveness of parenting programmes in improving psychosocial outcomes for teenage parents and developmental outcomes in their children.

**Search methods:** 
We searched to find new studies for this updated review in January 2008 and May 2010 in CENTRAL, MEDLINE, EMBASE, ASSIA, CINAHL, DARE, ERIC, PsycINFO, Sociological Abstracts and Social Science Citation Index. The National Research Register (NRR) was last searched in May 2005 and UK Clinical Research Network Portfolio Database in May 2010.

**Selection criteria:** 
Randomised controlled trials assessing short-term parenting interventions aimed specifically at teenage parents and a control group (no-treatment, waiting list or treatment-as-usual).

**Data collection and analysis:** 
We assessed the risk of bias in each study. We standardised the treatment effect for each outcome in each study by dividing the mean difference in post-intervention scores between the intervention and control groups by the pooled standard deviation.

**Main results:** 
We included eight studies with 513 participants, providing a total of 47 comparisons of outcome between intervention and control conditions. Nineteen comparisons were statistically significant, all favouring the intervention group. We conducted nine meta-analyses using data from four studies in total (each meta-analysis included data from two studies). Four meta-analyses showed statistically significant findings favouring the intervention group for the following outcomes: parent responsiveness to the child post-intervention (SMD -0.91, 95% CI -1.52 to -0.30, P = 0.04); infant responsiveness to mother at follow-up (SMD -0.65, 95% CI -1.25 to -0.06, P = 0.03); and an overall measure of parent-child interactions post-intervention (SMD -0.71, 95% CI -1.31 to -0.11, P = 0.02), and at follow-up (SMD -0.90, 95% CI -1.51 to -0.30, P = 0.004). The results of the remaining five meta-analyses were inconclusive.

**Authors&#039; conclusions:** 
Variation in the measures used, the included populations and interventions, and the risk of bias within the included studies limit the conclusions that can be reached. The findings provide some evidence to suggest that parenting programmes may be effective in improving a number of aspects of parent-child interaction both in the short- and long-term, but further research is now needed.
AN  - CD002964
AU  - Barlow,
AU  - J.
AU  - Smailagic,
AU  - N.
AU  - Bennett,
AU  - C.
AU  - Huband,
AU  - N.
AU  - Jones,
AU  - H.
AU  - Coren,
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd002964.pub2
KW  - Child Development
KW  - Age Factors
KW  - Mother-Child Relations
KW  - Parenting [psychology]
KW  - Program Evaluation
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Individual and group based parenting programmes for improving psychosocial outcomes for teenage parents and their children
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002964.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD002964.pub2/asset/CD002964.pdf?v=1&amp;t=iw7jpxi3&amp;s=eed225691e6cd336d42bea6dc0123483566b3095
ER  -
TY  - JOUR
AB  - AIM: 
The aim of this study was to investigate melatonin-related findings in autism spectrum disorders (ASD), including autistic disorder, Asperger syndrome, Rett syndrome, and pervasive developmental disorders, not otherwise specified. 

METHOD: 
Comprehensive searches were conducted in the PubMed, Google Scholar, CINAHL, EMBASE, Scopus, and ERIC databases from their inception to October 2010. Two reviewers independently assessed 35 studies that met the inclusion criteria. Of these, meta-analysis was performed on five randomized double-blind, placebo-controlled studies, and the quality of these trials was assessed using the Downs and Black checklist. 

RESULTS: 
Nine studies measured melatonin or melatonin metabolites in ASD and all reported at least one abnormality, including an abnormal melatonin circadian rhythm in four studies, below average physiological levels of melatonin and/or melatonin derivates in seven studies, and a positive correlation between these levels and autistic behaviors in four studies. Five studies reported gene abnormalities that could contribute to decreased melatonin production or adversely affect melatonin receptor function in a small percentage of children with ASD. Six studies reported improved daytime behavior with melatonin use. Eighteen studies on melatonin treatment in ASD were identified; these studies reported improvements in sleep duration, sleep onset latency, and night-time awakenings. Five of these studies were randomized double-blind, placebo-controlled crossover studies; two of the studies contained blended samples of children with ASD and other developmental disorders, but only data for children with ASD were used in the meta-analysis. The meta-analysis found significant improvements with large effect sizes in sleep duration (73 min compared with baseline, Hedge&#039;s g 1.97 [95% confidence interval {CI} CI 1.10-2.84], Glass&#039;s DELTA 1.54 [95% CI 0.64-2.44]; 44 min compared with placebo, Hedge&#039;s g 1.07 [95% CI 0.49-1.65], Glass&#039;s DELTA 0.93 [95% CI 0.33-1.53]) and sleep onset latency (66 min compared with baseline, Hedge&#039;s g-2.42 [95% CI -1.67 to -3.17], Glass&#039;s DELTA-2.18 [95% CI -1.58 to -2.76]; 39 min compared with placebo, Hedge&#039;s g-2.46 [95% CI -1.96 to -2.98], Glass&#039;s DELTA-1.28 [95% CI -0.67 to -1.89]) but not in night-time awakenings. The effect size varied significantly across studies but funnel plots did not indicate publication bias. The reported side effects of melatonin were minimal to none. Some studies were affected by limitations, including small sample sizes and variability in the protocols that measured changes in sleep parameters.

INTERPRETATION: 
Melatonin administration in ASD is associated with improved sleep parameters, better daytime behavior, and minimal side effects. Additional studies of melatonin would be helpful to confirm and expand on these findings.

Copyright &copy; The Authors. Developmental Medicine &amp; Child Neurology &copy; 2011 Mac Keith Press.
AD  - Rossignol,Daniel A. International Child Development Resource Center, Melbourne, FL, USA. rossignolmd@gmail.com
AN  - 21518346
AU  - Rossignol,
AU  - D.
AU  - A
AU  - Frye,
AU  - R.
AU  - E
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1469-8749.2011.03980.x
DP  - Ovid Technologies
J2  - Dev Med Child Neurol
KW  - Child *Child Development Disorders, Pervasive/dt [Drug Therapy] *Child Development Disorders, Pervasive/me [Metabolism] Child, Preschool Databases, Factual/sn [Statistics &amp; Numerical Data] Double-Blind Method Humans *Melatonin/me [Metabolism] *Melatonin
LA  - English
M3  - Meta-Analysis Review
N1  - Rossignol, Daniel A Frye, Richard E Comment in: Dev Med Child Neurol. 2011 Nov;53(11):1063; author reply 1064; PMID: 21838821
PY  - 2011
SP  - 783-92
T2  - Developmental Medicine &amp; Child Neurology
TI  - Melatonin in autism spectrum disorders: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21518346 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21518346&amp;id=doi:10.1111%2Fj.1469-8749.2011.03980.x&amp;issn=0012-1622&amp;isbn=&amp;volume=53&amp;issue=9&amp;spage=783&amp;pages=783-92&amp;date=2011&amp;title=Developmental+Medicine+%26+Child+Neurology&amp;atitle=Melatonin+in+autism+spectrum+disorders%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Rossignol&amp;pid=%3Cauthor%3ERossignol+DA%3C%2Fauthor%3E%3CAN%3E21518346%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1469-8749.2011.03980.x/asset/j.1469-8749.2011.03980.x.pdf?v=1&amp;t=ib7vawk5&amp;s=7c7cd98a9acfc0c36d3cbe9944534665f8bf93a1
VL  - 53
ER  -
TY  - JOUR
AB  - **Background:** 
Approximately 600 million children of preschool and school age are anaemic worldwide. It is estimated that half of the cases are due to iron deficiency. Consequences of iron deficiency anaemia during childhood include growth retardation, reduced school achievement, impaired motor and cognitive development, and increased morbidity and mortality. The provision of daily iron supplements is a widely used strategy for improving iron status in children but its effectiveness has been limited due to its side effects, which can include nausea, constipation or staining of the teeth. As a consequence, intermittent iron supplementation (one, two or three times a week on non-consecutive days) has been proposed as an effective and safer alternative to daily supplementation.

**Objectives:** 
To assess the effects of intermittent iron supplementation, alone or in combination with other vitamins and minerals, on nutritional and developmental outcomes in children from birth to 12 years of age compared with a placebo, no intervention or daily supplementation.

**Search methods:** 
We searched the following databases on 24 May 2011: CENTRAL (2011, Issue 2), MEDLINE (1948 to May week 2, 2011), EMBASE (1980 to 2011 Week 20), CINAHL (1937 to current), POPLINE (all available years) and WHO International Clinical Trials Registry Platform (ICTRP). On 29 June 2011 we searched all available years in the following databases: SCIELO, LILACS, IBECS and IMBIOMED. We also contacted relevant organisations (on 3 July 2011) to identify ongoing and unpublished studies.

**Selection criteria:** 
Randomised and quasi-randomised trials with either individual or cluster randomisation. Participants were children under the age of 12 years at the time of intervention with no specific health problems. The intervention assessed was intermittent iron supplementation compared with a placebo, no intervention or daily supplementation.

**Data collection and analysis:** 
Two authors independently assessed the eligibility of&nbsp;studies against the inclusion criteria, extracted data from included studies and assessed the risk of bias of the included studies.

**Main results:** 
We included 33 trials, involving 13,114 children (?49% females) from 20 countries in Latin America, Africa and Asia. The methodological quality of the trials was mixed.Nineteen trials evaluated intermittent iron supplementation versus no intervention or a placebo and 21 studies evaluated intermittent versus daily iron supplementation. Some of these trials contributed data to both comparisons. Iron alone was provided in most of the trials.Fifteen studies included children younger than 60 months; 11 trials included children 60 months and older, and seven studies included children in both age categories. One trial included exclusively females. Seven trials included only anaemic children; three studies assessed only non-anaemic children, and in the rest the baseline prevalence of anaemia ranged from 15% to 90%.In comparison with receiving no intervention or a placebo, children receiving iron supplements intermittently have a lower risk of anaemia (average risk ratio (RR) 0.51, 95% confidence interval (CI) 0.37 to 0.72, ten studies) and iron deficiency (RR 0.24, 95% CI 0.06 to 0.91, three studies) and have higher haemoglobin (mean difference (MD) 5.20&nbsp;g/L, 95% CI 2.51 to 7.88, 19 studies) and ferritin concentrations (MD 14.17&nbsp;&micro;g/L, 95% CI 3.53 to 24.81, five studies).Intermittent supplementation was as effective as daily supplementation in improving haemoglobin (MD ?0.60 g/L, 95% CI ?1.54 to 0.35, 19 studies) and ferritin concentrations (MD ?4.19&nbsp;&micro;g/L, 95% CI ?9.42 to 1.05, 10 studies), but increased the risk of anaemia in comparison with daily iron supplementation (RR 1.23, 95% CI 1.04 to1.47, six studies). Data on adherence were scarce and it tended to be higher among those children receiving intermittent supplementation, although this result was not statistically significant.We did not identify any differential effect of the type of intermittent supplementation regimen (one, two or three times a week), the total w e ly dose of elemental iron, the nutrient composition, whether recipients were male or female or the length of the intervention.

**Authors&#039; conclusions:** 
Intermittent iron supplementation is efficacious to improve haemoglobin concentrations and reduce the risk of having anaemia or iron deficiency in children younger than 12 years of age when compared with a placebo or no intervention, but it is less effective than daily supplementation to prevent or control anaemia. Intermittent supplementation may be a viable public health intervention in settings where daily supplementation has failed or has not been implemented. Information on mortality, morbidity, developmental outcomes and side effects, however, is still lacking.
AN  - CD009085
AU  - De-Regil,
AU  - L.
AU  - M.
AU  - Jefferds,
AU  - M.
AU  - E.
AU  - D.
AU  - Sylvetsky,
AU  - A.
AU  - C.
AU  - Dowswell,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd009085.pub2
KW  - Dietary Supplements
KW  - Anemia, Iron-Deficiency [blood] [complications] [drug therapy]
KW  - Child Development [drug effects]
KW  - Child Nutritional Physiological Phenomena [drug effects]
KW  - Drug Administration Schedule
KW  - Hemoglobin A, Glycosylated [metabolism]
KW  - Iron, Dietary [administration &amp; dosage]
KW  - Randomized Controlled Trials as Topic
KW  - Trace Elements [administration &amp; dosage]
KW  - Vitamins [administration &amp; dosage]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Behav
PY  - 2011
T2  - Cochrane Database of Systematic Reviews
TI  - Intermittent iron supplementation for improving nutrition and development in children under 12 years of age
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009085.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD009085.pub2/asset/CD009085.pdf?v=1&amp;t=iw7jssum&amp;s=49660ef68eb45b8ccfdfbd6bc821a7ebd840d8f6
ER  -
TY  - JOUR
AB  - **Objective: **
Risk of suicide attempt, suicidal ideation and deliberate self-harm is high among young people, yet limited evidence exists regarding effective interventions, particularly from randomized controlled trials. The aim of this study was to conduct a systematic review and meta-analysis of all randomized controlled trials testing interventions for adolescents and young adults who have presented to a clinical setting with any of these behaviours. 

**Methods: **
The Cochrane Central Register of Controlled Trials, Medline, EMBASE and PsycINFO were searched for articles published from 1980 to June 2010. The following keywords formed the basis of the search strategy: &#039;self-injurious behaviour&#039;, &#039;attempted suicide&#039;, &#039;suicide&#039;, &#039;suicidal behaviour&#039;, &#039;self-inflicted wounds&#039;, &#039;self-mutilation&#039;, &#039;self-harm&#039;. We also hand searched conference abstracts from two major suicide prevention conferences and the reference lists of all retrieved articles and previous reviews. 

**Results: **
There were 15 trials included in the review, with six ongoing trials also identified. In general, the reporting of the conduct of trials was poor, making it difficult to assess the risk of bias. The reporting of outcome data was inconsistent. No differences were found between treatment and control groups except in one study that found a difference between individual cognitive behavioural therapy and treatment as usual. 

**Conclusion: **
The evidence regarding effective interventions for adolescents and young adults with suicide attempt, deliberate self-harm or suicidal ideation is extremely limited. Many more methodologically rigorous trials are required. However, in the meantime CBT shows some promise, but further investigation is required in order to determine its ability to reduce suicide risk among young people presenting to clinical services.
AD  - [Robinson, Jo; Hetrick, Sarah E.; Martin, Cathy] Univ Melbourne, Youth Hlth Res Ctr, Ctr Youth Mental Hlth, Parkville, Vic 3052, Australia. Robinson, J (reprint author), Univ Melbourne, Youth Hlth Res Ctr, Ctr Youth Mental Hlth, Locked Bag 10, Parkville, Vic 3052, Australia. jr@unimelb.edu.au
AN  - WOS:000285507300002
AU  - Robinson,
AU  - J.
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Martin,
AU  - C.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3109/00048674.2010.511147
J2  - Aust. N. Z. J. Psych.
KW  - Deliberate self-harm randomized controlled trial suicide young people RANDOMIZED CONTROLLED-TRIAL DELIBERATE SELF-HARM NOMINATED SUPPORT TEAM INTERVENTION TRIAL CLINICAL-TRIALS GROUP-THERAPY ADOLESCENTS VERSION METAANALYSIS PARASUICIDE Psychiatry
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 697IP Times Cited: 24 Cited Reference Count: 46 Robinson, Jo Hetrick, Sarah E. Martin, Cathy Robinson, Jo/A-9035-2013 Colonial Foundation; NHMRC Orygen Youth Health receives funds from the Colonial Foundation. Sarah Hetrick is funded via a NHMRC training fellowship. The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper. 26 INFORMA HEALTHCARE NEW YORK AUST NZ J PSYCHIAT
PY  - 2011
SP  - 3-26
T2  - Australian and New Zealand Journal of Psychiatry
TI  - Preventing suicide in young people: systematic review
UR  - &lt;Go to ISI&gt;://WOS:000285507300002http://anp.sagepub.com/content/45/1/3.longhttp://anp.sagepub.com/content/45/1/3.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.3109/00048674.2010.511147?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 45
ER  -
TY  - JOUR
AB  - A systematic and meta-analytic review was conducted of the effectiveness of school-based mental health and behavioral programs for low-income, urban youth. 

Applying criteria from an earlier systematic review (Rones &amp; Hoagwood, 2000) of such programs for all populations indicated substantially fewer effective programs for low-income, urban youth. 

The meta-analysis similarly failed to indicate effects of the typical program on primary outcomes. Effectiveness was evident, however, for programs that targeted internalizing problems or had a broader socio-emotional focus and those delivered to all youth (i.e., universal). 

In contrast, negative effects were apparent for programs that targeted externalizing problems and were delivered selectively to youth with existing problems. 

Distinctive characteristics of low-income, urban schools and nonschool environments are emphasized as potential explanations for the findings.
AD  - [Farahmand, Farahnaz K.] Depaul Univ, Dept Psychol, Chicago, IL 60614 USA. [DuBois, David L.] Univ Illinois, Chicago, IL 60680 USA. Farahmand, FK (reprint author), Depaul Univ, Dept Psychol, 2219 N Kenmore Ave, Chicago, IL 60614 USA. ffarahma@depaul.edu
AN  - WOS:000298355100009
AU  - Farahmand,
AU  - F.
AU  - K.
AU  - Grant,
AU  - K.
AU  - E.
AU  - Polo,
AU  - A.
AU  - J.
AU  - Duffy,
AU  - S.
AU  - N.
AU  - DuBois,
AU  - D.
AU  - L.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1468-2850.2011.01265.x
J2  - Clin. Psychol.-Sci. Pract.
KW  - interventions low-income mental health services schools urban youth DEPRESSIVE SYMPTOMS PREVENTION PROGRAM AFRICAN-AMERICAN RISK YOUTH CHILDREN ADOLESCENTS INTERVENTION SERVICES VIOLENCE PSYCHOTHERAPY Psychology, Clinical
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 866BR Times Cited: 9 Cited Reference Count: 76 Farahmand, Farahnaz K. Grant, Kathryn E. Polo, Antonio J. Duffy, Sophia N. DuBois, David L. DuBois, David/F-9967-2013 DuBois, David/0000-0002-9955-7954 9 WILEY-BLACKWELL MALDEN CLIN PSYCHOL-SCI PR
PY  - 2011
SP  - 372-390
T2  - Clinical Psychology-Science and Practice
TI  - School-Based Mental Health and Behavioral Programs for Low-Income, Urban Youth: A Systematic and Meta-Analytic Review
UR  - &lt;Go to ISI&gt;://WOS:000298355100009http://onlinelibrary.wiley.com/store/10.1111/j.1468-2850.2011.01265.x/asset/j.1468-2850.2011.01265.x.pdf?v=1&amp;t=ib8ypq7h&amp;s=24daef481d702265a6d0e0b1c0c4226318e3b581
VL  - 18
ER  -
TY  - JOUR
AB  - BACKGROUND: 
The use of antipsychotics, especially second-generation antipsychotics (SGAs), for children with mental health disorders in Canada has increased dramatically over the past five years. These medications have the potential to cause major metabolic and neurological complications with chronic use.

OBJECTIVE: 
To synthesize the evidence for specific metabolic and neurological side effects associated with the use of SGAs in children, and provide evidence-based recommendations for the monitoring of these side effects.

METHODS: 
A systematic review of controlled clinical trials of SGAs involving children was performed. Recommendations for monitoring SGA safety were made according to a classification scheme based on the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system. When there was inadequate evidence, recommendations were based on consensus and expert opinion. A multidisciplinary consensus group reviewed all relevant evidence and reached consensus on the recommendations.

RESULTS: 
The present guidelines provide evidence-based recommendations for monitoring SGA safety. The strength of recommendations for specific physical examination manoeuvres and laboratory tests are provided for each SGA medication at specific time points.

CONCLUSION: 
Multiple randomized controlled trials evaluated the efficacy of many of the SGAs in paediatric mental health disorders. These benefits, however, are not without risks - both metabolic and neurological side effects occur in children treated with SGAs. The risk of weight gain, increased body mass index and abnormal lipid levels is greatest with olanzapine, followed by clozapine and quetiapine. The risk of neurological side effects of the treatment is greatest with risperidone, olanzapine and aripiprazole. Appropriate monitoring procedures for adverse effects will improve the quality of care of children treated with these medications.
AD  - Pringsheim, Tamara. Department of Clinical Neurosciences and Pediatrics, University of Calgary, Calgary, Alberta;
AN  - 23115502
AU  - Pringsheim,
AU  - T.
AU  - Panagiotopoulos,
AU  - C.
AU  - Davidson,
AU  - J.
AU  - Ho,
AU  - J.
AU  - Canadian
AU  - Alliance
AU  - for
AU  - Monitoring,
AU  - Effectiveness
AU  - Safety
AU  - of
AU  - Antipsychotics
AU  - in
AU  - Children
AU  - guideline,
AU  - group
DA  - Nov
DB  - Rekoding IN SUM_lme.enl
DO  - https://dx.doi.org/Har ikke DOI følg lenke: https://www.ncbi.nlm.nih.gov/pubmed/21804853
DP  - Ovid Technologies
J2  - Paediatr child health
L1  - internal-pdf://3615010832/Pringsheim-2011.pdf
LA  - English
N1  - (CAMESA)Pringsheim, TamaraPanagiotopoulos, ConstadinaDavidson, JanaHo, JosephineCanadian Alliance for Monitoring Effectiveness and Safety of Antipsychotics in Children (CAMESA) guideline group
PY  - 2011
SP  - 581-9
T2  - Paediatrics &amp; Child Health
TI  - Evidence-based recommendations for monitoring safety of second-generation antipsychotics in children and youth
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=23115502
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23115502&amp;id=doi:&amp;issn=1205-7088&amp;isbn=&amp;volume=16&amp;issue=9&amp;spage=581&amp;pages=581-9&amp;date=2011&amp;title=Paediatrics+%26+Child+Health&amp;atitle=Evidence-based+recommendations+for+monitoring+safety+of+second-generation+antipsychotics+in+children+and+youth.&amp;aulast=Pringsheim&amp;pid=%3Cauthor%3EPringsheim+T%3C%2Fauthor%3E%3CAN%3E23115502%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 16
ER  -
TY  - JOUR
AB  - The purpose of this study was to provide a comprehensive review of the effectiveness of child and adolescent anxiety prevention programs. 
Mean weighted effect sizes were calculated, and studies were encoded for potential moderator variables. 

A statistically significant effect size of .18 was obtained at post-intervention, which is consistent with effect sizes reported in reviews of depression, eating disorder, and substance abuse prevention programs. 

However, the effect sizes obtained at follow-up yielded mixed results. Significant moderators of program effectiveness were found including provider type (professional versus lay provider) and the use of the FRIENDS program. 

In contrast, program duration, participant age, gender, and program type (universal versus targeted) were not found to moderate program effectiveness. 

Clinical implications and directions for future research are discussed, including the need for more long-term follow-up, early prevention programs, and studies that systematically examine the impact of parent involvement on program effectiveness.

Copyright &copy; Society for Prevention Research 2011
AD  - Fisak,Brian J Jr. University of North Florida, Jacksonville, FL, USA. b.fisak@unf.edu
AN  - 21437675
AU  - Fisak,
AU  - B.
AU  - J.
AU  - Richard,
AU  - D.
AU  - Mann,
AU  - A.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s11121-011-0210-0
DP  - Ovid Technologies
J2  - Prev Sci
KW  - Adolescent *Anxiety/pc [Prevention &amp; Control] Child Humans
LA  - English
M3  - Meta-Analysis Review
N1  - Fisak, Brian J Jr Richard, Dan Mann, Angela
PY  - 2011
SP  - 255-68
T2  - Prevention Science
TI  - The prevention of child and adolescent anxiety: a meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21437675 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21437675&amp;id=doi:10.1007%2Fs11121-011-0210-0&amp;issn=1389-4986&amp;isbn=&amp;volume=12&amp;issue=3&amp;spage=255&amp;pages=255-68&amp;date=2011&amp;title=Prevention+Science&amp;atitle=The+prevention+of+child+and+adolescent+anxiety%3A+a+meta-analytic+review.&amp;aulast=Fisak+BJ&amp;pid=%3Cauthor%3EFisak+BJ+Jr%3C%2Fauthor%3E%3CAN%3E21437675%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://media.proquest.com/media/pq/classic/doc/2420224461/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Fisak%2C+Brian+J%2C+Jr%3BRichard%2C+Dan%3BMann%2C+Angela&amp;cit%3Atitle=The+Prevention+of+Child+and+Adolescent+Anxiety%3A+A+Meta-analytic+Review&amp;cit%3Apub=Prevention+Science&amp;cit%3Avol=12&amp;cit%3Aiss=3&amp;cit%3Apg=255&amp;cit%3Adate=Sep+2011&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMjA2MzQ0MzIxNDoyODMyNzMSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNDQ3MDkyCTg4MTcwNDM2MjoNRG9jdW1lbnRJbWFnZUIBMFIGT25saW5lWgJGVGIDUEZUagoyMDExLzA5LzAxcgoyMDExLzA5LzMwegCCASlQLTEwMDAyNzMtMzEwNzUtQ1VTVE9NRVItMTAwMDAxNTctMTExNTExMpIBBk9ubGluZcoBB0VuZE5vdGXSARJTY2hvbGFybHkgSm91cm5hbHOaAgdQcmVQYWlkqgIoT1M6RU1TLVBkZkRvY1ZpZXdCYXNlLWdldE1lZGlhVXJsRm9ySXRlbcoCD0FydGljbGV8RmVhdHVyZdICAVniAgFO8gIA&amp;_s=5UD7cTCoLZIklopGA%2BkJ3KPCTno%3D
UR  - https://link.springer.com/article/10.1007%2Fs11121-011-0210-0
VL  - 12
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Available evidence indicates that the use of antipsychotics, especially second-generation antipsychotics (SGAs), for children with mental health disorders has increased dramatically. Given the demonstrated metabolic and neurological adverse effects seen in adult patients on these medications, detailed evaluation of the risk for these adverse effects in children is appropriate. 

**OBJECTIVE: **
The aim of the study was to assess the evidence for specific metabolic and neurological adverse effects associated with the use of SGAs in children. 

**DATA SOURCES: **
MEDLINE (1996-May 2010) and EMBASE (1996-May 2010) databases were searched using highly sensitive search strategies for clinical trials in a paediatric population (children up to age 18 years). 

**STUDY SELECTION:** 
We included any double-blind, randomized controlled trial (RCT) of SGA medications conducted specifically in a paediatric population for the treatment of a mental health disorder. This included the medications risperidone, olanzapine, quetiapine, aripiprazole, clozapine, ziprasidone and paliperidone. The primary outcomes assessed for this review were metabolic and neurological adverse effects, as measured using physical examination manoeuvres, rating scales or laboratory tests. A total of 35 RCTs were included in the analysis, but not all studies had data that could be used in the meta-analysis. 

**DATA EXTRACTION: **
Abstracts retrieved from the searches were reviewed independently by two different reviewers for potential relevant articles. Full-text articles were then read in detail independently by two different reviewers to see if inclusion criteria were fulfilled. Data were extracted independently by two review authors from included studies and entered onto pre-designed summary forms. Clinical trials were evaluated for methodological quality using quality criteria developed by the US Preventive Services Task Force. Based on the fulfilment of quality criteria, studies were rated as good, fair or poor. 

**DATA SYNTHESIS: **
Meta-analysis was performed on the data for synthesis, and was carried out for commonly reported outcomes for each medication individually, in comparison with placebo or another drug. Odds ratios (ORs) with 95% confidence intervals for binary outcomes were used. For continuous outcomes, mean differences were used to analyze the data. Meta-analysis revealed that mean weight gain compared with placebo was highest for olanzapine at 3.47kg (95% CI 2.94, 3.99) followed by risperidone at 1.72kg (95% CI 1.17, 2.26), quetiapine at 1.41kg (95% CI 1.10, 1.81) and aripiprazole at 0.85kg (95% CI 0.58, 1.13). Olanzapine and clozapine treatment were associated with the highest rate of metabolic laboratory abnormalities in cholesterol and triglycerides. Prolactin elevation occurred with risperidone and olanzapine therapy. Higher odds of extrapyramidal symptoms compared with placebo were seen in children treated with risperidone (OR 3.55; 95% CI 2.04, 5.48) and aripiprazole (OR 3.70; 95% CI 2.37, 5.77). Elevated rates of extrapyramidal symptoms were also experienced with olanzapine use. 

**CONCLUSIONS: **
There is good evidence to support the existence of both metabolic and neurological adverse effects in children treated with these medications. Proper attention and vigilance to potential metabolic and neurological adverse effects is necessary, and should be considered part of the standard of care.
AD  - Pringsheim,Tamara. University of Calgary, Calgary, AB, Canada. tmprings@ucalgary.ca
AN  - 21751826
AU  - Pringsheim,
AU  - T.
AU  - Lam,
AU  - D.
AU  - Ching,
AU  - H.
AU  - Patten,
AU  - S.
DA  - Aug 1
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.2165/11592020-000000000-00000
DP  - Ovid Technologies
J2  - Drug Saf
KW  - Adolescent *Antipsychotic Agents/ae [Adverse Effects] Child Child, Preschool Humans Infant *Mental Disorders/dt [Drug Therapy] *Metabolic Diseases/ci [Chemically Induced] *Nervous System Diseases/ci [Chemically Induced] Randomized Controlled Trials as T
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Pringsheim, Tamara Lam, Darren Ching, Heidi Patten, Scott (Canada Canadian Institutes of Health Research)
PY  - 2011
SP  - 651-68
T2  - Drug Safety
TI  - Metabolic and neurological complications of second-generation antipsychotic use in children: a systematic review and meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medl&amp;AN=21751826
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21751826&amp;id=doi:10.2165%2F11592020-000000000-00000&amp;issn=0114-5916&amp;isbn=&amp;volume=34&amp;issue=8&amp;spage=651&amp;pages=651-68&amp;date=2011&amp;title=Drug+Safety&amp;atitle=Metabolic+and+neurological+complications+of+second-generation+antipsychotic+use+in+children%3A+a+systematic+review+and+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Pringsheim&amp;pid=%3Cauthor%3EPringsheim+T%3C%2Fauthor%3E%3CAN%3E21751826%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://media.proquest.com/media/pq/classic/doc/2398424031/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Pringsheim%2C+Tamara%3BLam%2C+Darren%3BChing%2C+Heidi%3BPatten%2C+Scott&amp;cit%3Atitle=Metabolic+and+Neurological+Complications+of+Second-Generation+...&amp;cit%3Apub=Drug+Safety&amp;cit%3Avol=34&amp;cit%3Aiss=8&amp;cit%3Apg=651&amp;cit%3Adate=Aug+2011&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMjEyMjgxNjU5Mjo5OTU1MjQSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFMzIxODcyCTg3NjI4MTkzNDoNRG9jdW1lbnRJbWFnZUIBMFIGT25saW5lWgJGVGIDUEZUagoyMDExLzA4LzAxcgoyMDExLzA4LzMxegCCASlQLTEwMDAyNzMtMzEwNzUtQ1VTVE9NRVItMTAwMDAxNTctMTExNTExMpIBBk9ubGluZcoBB0VuZE5vdGXSARJTY2hvbGFybHkgSm91cm5hbHOaAgdQcmVQYWlkqgIoT1M6RU1TLVBkZkRvY1ZpZXdCYXNlLWdldE1lZGlhVXJsRm9ySXRlbcoCGVVuZGVmaW5lZHxBcnRpY2xlfEZlYXR1cmXSAgFZ4gIBTvICAA%3D%3D&amp;_s=zMMPVWNuylr2NRzyvEF15j%2FMrx8%3D
UR  - https://link.springer.com/article/10.2165%2F11592020-000000000-00000
VL  - 34
ER  -
TY  - JOUR
AB  - **Objective: **
Several studies have demonstrated differences in omega-3 fatty acid composition in plasma and in erythrocyte membranes in patients with attention-deficit/hyperactivity disorder (ADHD) compared with unaffected controls. Omega-3 fatty acids have anti-inflammatory properties and can alter central nervous system cell membrane fluidity and phospholipid composition. Cell membrane fluidity can alter serotonin and dopamine neurotransmission. The goal of this meta-analysis was to examine the efficacy of omega-3 fatty acid supplementation in children with ADHD. 

**Method: **
Pub Med was searched for randomized placebo-controlled trials examining omega-3 fatty acid supplementation in children with ADHD symptomatology. The primary outcome measurement was standardized mean difference in rating scales of ADHD severity. Secondary analyses were conducted to determine the effects of dosing of different omega-3 fatty acids in supplements. 

**Results: **
Ten trials involving 699 children were included in this meta-analysis. Omega-3 fatty acid supplementation demonstrated a small but significant effect in improving ADHD symptoms. Eicosapentaenoic acid dose within supplements was significantly correlated with supplement efficacy. No evidence of publication bias or heterogeneity between trials was found. 

**Conclusion: **
Omega-3 fatty acid supplementation, particularly with higher doses of eicosapentaenoic acid, was modestly effective in the treatment of ADHD. The relative efficacy of omega-3 fatty acid supplementation was modest compared with currently available pharmacotherapies for ADHD such as psychostimulants, atomoxetine, or alpha(2) agonists.

However, given its relatively benign side-effect profile and evidence of modest efficacy, it may be reasonable to use omega-3 fatty supplementation to augment traditional pharmacologic interventions or for families who decline other psychopharmacologic options.

 J. Am. Acad. Child Adolesc. Psychiatry, 2011;50(10):991-1000.
AD  - [Bloch, Michael H.] Yale Univ, Sch Med, Ctr Child Study, New Haven, CT 06520 USA. [Qawasmi, Ahmad] Al Quds Univ, Child Inst, Jerusalem, Israel. Bloch, MH (reprint author), Yale Univ, Sch Med, Ctr Child Study, POB 2070900, New Haven, CT 06520 USA. michael.bloch@yale.edu
AN  - WOS:000295562700007
AU  - Bloch,
AU  - M.
AU  - H.
AU  - Qawasmi,
AU  - A.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jaac.2011.06.008
J2  - J. Am. Acad. Child Adolesc. Psychiatr.
KW  - attention-deficit disorder with hyperactivity polyunsaturated fatty acids omega-3 fatty acids eicosapentaenoic acid meta-analysis DEFICIT-HYPERACTIVITY DISORDER PLACEBO-CONTROLLED TRIAL RANDOMIZED CONTROLLED-TRIALS POLYUNSATURATED FATTY-ACIDS DOUBLE-BLI
L1  - internal-pdf://4084170844/Bloch-2011-Omega-3 Fatty Acid Supplementation.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 829EZ Times Cited: 51 Cited Reference Count: 50 Bloch, Michael H. Qawasmi, Ahmad National Institute of Mental Health; National Institutes of Health (NIH) [1K23MH091240-01]; American Psychiatric Institute for Research and Education (APIRE)/Eli Lilly and Co.; American Academy of Child and Adolescent Psychiatry/Eli Lilly and Co.; Trichotillomania Learning Center; National Alliance for Research on Schizophrenia and Depression; National Center for Research Resources, NIH [UL1 RR024139]; NIH Roadmao for Medical Research The authors acknowledge the National Institute of Mental Health support of the Yale Child Study Center Research Training Program (MHB), National Institutes of Health (NIH) grant 1K23MH091240-01 (MHB), the American Psychiatric Institute for Research and Education (APIRE)/Eli Lilly and Co. Psychiatric Research Fellowship (MHB), the American Academy of Child and Adolescent Psychiatry/Eli Lilly and Co. Pilot Research Award (MHB), the Trichotillomania Learning Center (MHB), the National Alliance for Research on Schizophrenia and Depression (MHB), and grant UL1 RR024139 from the National Center for Research Resources, a component of the NIH, and the NIH Roadmao for Medical Research (MHB). 51 ELSEVIER SCIENCE BV AMSTERDAM J AM ACAD CHILD PSY
PY  - 2011
SP  - 991-1000
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Omega-3 Fatty Acid Supplementation for the Treatment of Children With Attention-Deficit/Hyperactivity Disorder Symptomatology: Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000295562700007http://ac.els-cdn.com/S0890856711004849/1-s2.0-S0890856711004849-main.pdf?_tid=1e4a7c9a-1674-11e5-818e-00000aacb360&amp;acdnat=1434712548_aec2632f4c80d64e80f2f986b6fa9a2d
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625948/pdf/454652.pdf
VL  - 50
ER  -
TY  - JOUR
AB  - **Background **
Alcohol misuse in young people is cause of concern for health services, policy makers, prevention workers, criminal justice system, youth workers, teachers, parents. This is one of three reviews examining the effectiveness of (1) school-based, (2) family-based, and (3) multi-component prevention programs. 

**Objectives **
To review evidence on the effectiveness of universal school-based prevention programs in preventing alcohol misuse in school-aged children up to 18 years of age.

**Search strategy **
Relevant evidence (up to 2002) was selected from the previous Cochrane review. Later studies, to July 2010, were identified from MEDLINE, Cochrane Central Register of Controlled Trials, EMBASE, Project CORK, and PsycINFO. 

**Selection criteria **
Randomized trials evaluating universal school-based prevention programs and reporting outcomes for alcohol use in students 18 years of age or younger were included. Two reviewers screened titles/abstracts and full text of identified records. 

**Data collection and analysis **
Two reviewers extracted relevant data independently using an a priori defined extraction form. Risk of bias was assessed. 

**Main results **
53 trials were included, most of which were cluster-randomised. The reporting quality of trials was poor, only 3.8% of them reporting adequate method of randomisation and program allocation concealment. Incomplete data was adequately addressed in 23% of the trials. Due to extensive heterogeneity across interventions, populations, and outcomes, the results were summarized only qualitatively. Six of the 11 trials evaluating alcohol-specific interventions showed some evidence of effectiveness compared to a standard curriculum. In 14 of the 39 trials evaluating generic interventions, the program interventions demonstrated significantly greater reductions in alcohol use either through a main or subgroup effect. Gender, baseline alcohol use, and ethnicity modified the effects of interventions. Results from the remaining 3 trials with interventions targeting cannabis, alcohol, and/or tobacco were inconsistent. 

**Authors&#039; conclusions **
This review identified studies that showed no effects of preventive interventions, as well as studies that demonstrated statistically significant effects. There was no easily discernible pattern in characteristics that would distinguish trials with positive results from those with no effects. Most commonly observed positive effects across programs were for drunkenness and binge drinking. Current evidence suggests that certain generic psychosocial and developmental prevention programs can be effective and could be considered as policy and practice options. These include the Life Skills Training Program, the Unplugged program, and the Good Behaviour Game. A stronger focus of future research on intervention program content and delivery context is warranted. 

**PLAIN LANGUAGE SUMMARY **
Psychosocial and Development Alcohol Misuse Prevention in Schools can be effective We conducted a Cochrane systematic review of 53 well-designed experimental studies that examined the effectiveness of school-based universal programs for the prevention of alcohol misuse in young people. The studies were divided into two major groups based on the nature of the prevention program: 1) programs targeting specifically prevention or reduction of alcohol misuse and 2) generic programs with wider focus for prevention (e. g., other drug use/abuse, antisocial behavior). In the review we found studies that showed no effects of the preventive program, as well as studies that demonstrated statistically significant effects. There was no easily discernible pattern in program characteristics that would distinguish studies with positive results from those with no effects. Most commonly observed positive effects across programs were for drunkenness and binge drinking. In conclusion, current evidence suggests that certain generic psychosocial and developmental prevention programs can be effective and could be considered as policy and practice options. These include the Life Skills Training Program, the Unplugge program, and the Good Behaviour Game.
AD  - [Foxcroft, David R.] Oxford Brookes Univ, Sch Hlth &amp; Social Care, Oxford OX3 0FL, England. [Tsertsvadze, Alexander] Univ Ottawa, Ottawa Hosp Res Inst, Evidence Based Practice Ctr, Clin Epidemiol Methods Ctr, Ottawa, ON, Canada. Foxcroft, DR (reprint author), Oxford Brookes Univ, Sch Hlth &amp; Social Care, Marston Rd,Jack Straws Lane, Oxford OX3 0FL, England. david.foxcroft@brookes.ac.uk
AN  - WOS:000290496400028
AU  - Foxcroft,
AU  - D.
AU  - R.
AU  - Tsertsvadze,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD009113
J2  - Cochrane Database Syst Rev.
KW  - RANDOMIZED CONTROLLED-TRIAL DRUG-ABUSE PREVENTION AMERICAN FAMILIES PROGRAM HARM REDUCTION PROJECT RAISING HEALTHY-CHILDREN SUBSTANCE USE INITIATION 7TH GRADE STUDENTS LIONS-QUEST SKILLS FOLLOW-UP EDUCATION-PROGRAM Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 762RB Times Cited: 24 Cited Reference Count: 156 Foxcroft, David R. Tsertsvadze, Alexander Oxford Brookes University, UK; NIHR, UK Internal sourcesOxford Brookes University, UK.Funding to employ a co-reviewerExternal sourcesNIHR, UK.Small grant for updating the previous review 24 WILEY-BLACKWELL HOBOKEN COCHRANE DB SYST REV
PY  - 2011
SP  - 122
T2  - Cochrane Database of Systematic Reviews
TI  - Universal school-based prevention programs for alcohol misuse in young people
UR  - &lt;Go to ISI&gt;://WOS:000290496400028http://onlinelibrary.wiley.com/store/10.1002/14651858.CD009113/asset/CD009113.pdf?v=1&amp;t=ib7tdx6j&amp;s=2b3f791681db2bd2ffa6afe4ae7d0d89bbfa8c3c
ER  -
TY  - JOUR
AB  - **Background **
Attention Deficit Hyperactivity Disorder (ADHD) in children is associated with hyperactivity and impulsitivity, attention problems, and difficulties with social interactions. Pharmacological treatment may alleviate symptoms of ADHD but seldom solves difficulties with social interactions. Social skills training may benefit ADHD children in their social interactions. We examined the effects of social skills training on children&#039;s social competences, general behaviour, ADHD symptoms, and performance in school. 

**Objectives **
To assess the effects of social skills training in children and adolescents with ADHD. Search methods We searched the following electronic databases: CENTRAL (2011, Issue1), MEDLINE (1948 to March 2011), EMBASE (1980 to March 2011), ERIC (1966 to March 2011), AMED (1985 to June 2011), PsycINFO (1806 to March 2011), CINAHL (1980 to March 2011), and Sociological Abstracts (1952 to March 2011). We also searched the metaRegister of Controlled Trials on 15 October 2010. We did not apply any language or date restrictions to the searches. We searched online conference abstracts and contacted 176 experts in the field for possible information about unpublished or ongoing RCTs. 

**Selection criteria **
Randomised trials investigating social skills training for children with ADHD as a stand alone treatment or as an adjunct to pharmacological treatment. 

**Data collection and analysis **
We conducted the review according to the Cochrane Handbook for Systematic Reviews of Intervention. Two authors (OJS, MS) extracted data independently using an appropriate data collection form. We performed the analyses using Review Manager 5 software. 

**Main results **
We included 11 randomised trials described in 26 records (all full text articles) in the review. The trials included a total of 747 participants. All participants were between five and 12 years of age. No trials assessed adolescents. In 10 of the trials the participants suffered from different comorbidities. The duration of the interventions ranged from eight to 10 weeks (eight trials) up to two years. The types of social skills interventions were named social skills training, cognitive behavioural intervention, multimodal behavioural/psychosocial therapy, behavioural therapy/treatment, behavioural and social skills treatment, and psychosocial treatment. The content of the social skills interventions were comparable and based on a cognitive behavioural model. Most of the trials compared child social skills training and parent training plus medication versus medication alone. Some of the experimental interventions also included teacher consultations. More than half of the trials were at high risk of bias regarding generation of the allocation sequence and allocation concealment. No trial reported blinding of participants and personnel and most of the trials had no reports regarding differences between groups in collateral medication for comorbid disorders. Overall, the trials had high risk of bias due to systematic errors. Even so, as recommended by the Cochrane Handbook of Systematic Reviews of Interventions, we used all eligible trials in the meta-analysis, but the results are downgraded to low quality evidence. There were no statistically significant treatment effects either on social skills competences (positive value = better for the intervention group) (SMD 0.16; 95% CI -0.04 to 0.36; 5 trials, n = 392), on the teacher-rated general behaviour (negative value = better for the intervention group) (SMD 0.00; 95% CI -0.21 to 0.21; 3 trials, n = 358), or on the ADHD symptoms (negative value = better for the intervention group) (SMD -0.02; 95% CI -0.19 to 0.16; 6 trials, n = 515). No serious or non-serious adverse events were reported. 

**Authors&#039; conclusions **
The review suggests that there is little evidence to support or refute social skills training for adolescents with ADHD. There is need for more trials, with low risk of bias and with a sufficient number of participants, investigating the efficacy of social skills training versus no training for both children and adolesc nts.
AD  - [Storebo, Ole Jakob; Simonsen, Erik] Univ Copenhagen Hosp, Rigshosp, Dept 3344, Copenhagen Trial Unit,Ctr Clin Intervent Res,Coch, DK-2100 Copenhagen, Denmark. [Storebo, Ole Jakob] Region Zealand, Child Psychiat Clin, Dept Psychiat, Holbaek, Denmark. [Damm, Dorte; Thomsen, Per Hove] Psychiat Hosp Children &amp; Adolescents, Risskov, Denmark. [Simonsen, Erik] Reg Zealand Psychiat, Psychiat Res Unit, Roskilde, Denmark. [Storebo, Ole Jakob] Reg Sjaelland, Bornepsykiatr Ambulatorium, Holbaek, Denmark. Storebo, OJ (reprint author), Univ Copenhagen Hosp, Rigshosp, Dept 3344, Copenhagen Trial Unit,Ctr Clin Intervent Res,Coch, DK-2100 Copenhagen, Denmark. ojst@regionsjaelland.dk
AN  - WOS:000300937600063
AU  - Storebo,
AU  - O.
AU  - J.
AU  - Skoog,
AU  - M.
AU  - Damm,
AU  - D.
AU  - Thomsen,
AU  - P.
AU  - H.
AU  - Simonsen,
AU  - E.
AU  - Gluud,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD008223.pub2
J2  - Cochrane Database Syst Rev.
KW  - LONG-TERM METHYLPHENIDATE MULTIMODAL PSYCHOSOCIAL TREATMENT TRIAL SEQUENTIAL-ANALYSIS DEFICIT/HYPERACTIVITY-DISORDER BEHAVIOR-MODIFICATION FOLLOW-UP CUMULATIVE METAANALYSIS TREATMENT STRATEGIES CONDUCT PROBLEMS ACADEMIC-PERFORMANCE Medicine, General &amp; I
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 901BV Times Cited: 10 Cited Reference Count: 151 Storebo, Ole Jakob Skoog, Maria Damm, Dorte Thomsen, Per Hove Simonsen, Erik Gluud, Christian Gluud, Christian/K-2561-2013; Simonsen, Erik/N-6615-2014 Simonsen, Erik/0000-0002-6134-2392 NOVARTIS; UCB; CopenhagenTrial Unit, Denmark; Research Library, Unit for Psychiatric Research, Region Zealand, Roskilde, Denmark; Trygfonden (Denmark) Per Hove Thomsen has received fees for lecturing on behalf of the pharmacological companies: NOVARTIS and UCB and lecturing and consulting on behalf of Eli-Lilly. He also serves on the advisory board of Eli-Lilly.CopenhagenTrial Unit, Denmark.Research Library, Unit for Psychiatric Research, Region Zealand, Roskilde, Denmark.We would like to acknowledge the contribution from Trygfonden (Denmark) for their financial support completion of this review. 10 WILEY-BLACKWELL MALDEN COCHRANE DB SYST REV
PY  - 2011
SP  - 89
T2  - Cochrane Database of Systematic Reviews
TI  - Social skills training for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 5 to 18 years
UR  - &lt;Go to ISI&gt;://WOS:000300937600063http://onlinelibrary.wiley.com/store/10.1002/14651858.CD008223.pub2/asset/CD008223.pdf?v=1&amp;t=ib7usf2h&amp;s=ad0dbfa937a2f62e3d408b2139a4c6c5c2c3cef7
ER  -
TY  - JOUR
AB  - **Aims** 
A systematic review and meta-analysis was conducted to assess the methodological quality and effectiveness of behavioural smoking cessation interventions targeted at six disadvantaged groups; the homeless, prisoners, indigenous populations, at-risk youth, individuals with low socio-economic status and individuals with a mental illness. 

**Methods**
Medline, EMBASE, the Cochrane Library and PsycInfo databases were searched using MeSH and keywords for studies conducted in developed countries prior to October 2010. Included studies were assessed for methodological quality. A DerSimonian and Laird random effects meta-analysis was conducted where possible to explore the effectiveness of interventions for the different subgroups. A narrative review was conducted for studies unable to be included in the meta-analysis. Outcomes examined were abstinence rates at short-term(up to 3 months) and long-term(6 months or the longest) follow-up. 

**Results**
Thirty-two relevant studies were identified. The majority (n = 20) were rated low in methodological quality. Results of the meta-analysis showed a significant increase in cessation for behavioural support interventions targeted at low-income female smokers at short-term follow-up [relative risk (RR) 1.68, confidence interval (CI) 1.21-2.33], and behavioural support interventions targeted at individuals with a mental illness at long-term follow-up (RR 1.35, CI 1.01-1.81). Results of the narrative review showed several promising interventions that increased cessation rates at 6-month or longer follow-up. 

**Conclusions**
Few well-controlled trials have examined the most effective smoking cessation strategies for highly disadvantaged groups, especially among the homeless, indigenous smokers and prisoners. The use of behavioural smoking cessation interventions for some socially disadvantaged groups appears promising; however, overall findings are inconsistent. Further research is needed to establish the most effective interventions for vulnerable high-risk groups. Special attention should be given to increasing sample size and power, and to sound evaluation methodology to overcome methodological limitations of conducting research with these high-risk groups.
AD  - [Bryant, Jamie; Bonevski, Billie] Univ Newcastle, CHeRP, NSW Canc Council, Callaghan, NSW 2308, Australia. [Paul, Chris] Univ Newcastle, Hlth Behav Res Grp, Sch Med &amp; Publ Hlth, Callaghan, NSW 2308, Australia. [Bryant, Jamie; Bonevski, Billie; McElduff, Patrick] Hunter Med Res Inst, Callaghan, NSW 2308, Australia. [Attia, John] Univ Newcastle, Newcastle, NSW 2300, Australia. [Attia, John] John Hunter Hosp, Hunter Med Res Inst, Hunter Reg Mail Ctr, Newcastle, NSW, Australia. Bryant, J (reprint author), Univ Newcastle, CHeRP, NSW Canc Council, Room 230A,Level 2,David Maddison Bldg, Callaghan, NSW 2308, Australia. jamie.bryant@newcastle.edu.au
AN  - WOS:000293619300007
AU  - Bryant,
AU  - J.
AU  - Bonevski,
AU  - B.
AU  - Paul,
AU  - C.
AU  - McElduff,
AU  - P.
AU  - Attia,
AU  - J.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1360-0443.2011.03467.x
J2  - Addiction
KW  - Homeless persons indigenous population low income population mentally ill prisoners review smoking cessation RANDOMIZED CONTROLLED-TRIAL PUBLIC-HEALTH CLINICS CIGARETTE-SMOKING MENTAL-ILLNESS SPECIAL POPULATIONS COST-EFFECTIVENESS TOBACCO CESSATION PREG
L1  - internal-pdf://1839709806/Bryant-2011-A systematic review and meta-analy.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 803YP Times Cited: 24 Cited Reference Count: 90 Bryant, Jamie Bonevski, Billie Paul, Chris McElduff, Patrick Attia, John Attia, John/F-5376-2013 Attia, John/0000-0001-9800-1308 24 WILEY-BLACKWELL MALDEN ADDICTION
PY  - 2011
SP  - 1568-1585
T2  - Addiction
TI  - A systematic review and meta-analysis of the effectiveness of behavioural smoking cessation interventions in selected disadvantaged groups
UR  - &lt;Go to ISI&gt;://WOS:000293619300007http://onlinelibrary.wiley.com/store/10.1111/j.1360-0443.2011.03467.x/asset/j.1360-0443.2011.03467.x.pdf?v=1&amp;t=ib3l2lmy&amp;s=f3782d3171081a80e449fb704b55228f9809780a
UR  - http://onlinelibrary.wiley.com/store/10.1111/j.1360-0443.2011.03467.x/asset/j.1360-0443.2011.03467.x.pdf?v=1&amp;t=j8yewkha&amp;s=589fc70333c9065cb582c640ac9e7f69a796de49
VL  - 106
ER  -
TY  - JOUR
AB  - [Correction Notice: An erratum for this article was reported in Vol 11(2) of International Journal of Clinical and Health Psychology (see record 2011-10215-011). In the original article, Table 3 was incorrect. The corrected Table 3 is given in the erratum.] 

By means of a meta-analytic review, the current study investigated the efficacy of the psychological treatment of children and adolescents that have suffered sexual abuse. Thirty-three articles met our selection criteria and, using the group as the analysis unit, the meta-analytic database was composed of 44 treatment groups and 7 control groups. 

The effect size index was the standardized mean change between the pretest and the posttest means, and it was separately applied for different outcome measures (sexualised behaviours, anxiety, depression, self-esteem, behaviour problems, and other outcomes) and assessment methods (child self-reports, parent reports, and clinician assessments). For all of the outcome measures, the mean effect size for the treatment groups was statistically and clinically significant, whereas the control groups did not achieve a significant improvement. 

Significant differences among the various psychological treatment approaches were found for the global outcome measure, sexualised behaviours, and behaviour problems. In general, trauma-focused cognitive-behavioural treatments combined with supportive therapy and a psychodynamic element (e.g., play therapy) showed the best results. Finally, the implications for clinical practice and for future research of the results in this field are discussed. 

(PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Sanchez-Meca, Julio: jsmeca@um.es Sanchez-Meca, Julio: Dept. Psicologia Basica y Metodologia, Facultad de Psicologia, Universidad de Murcia, Campus de Espinardo, Murcia, Spain, 30100, jsmeca@um.es Sanchez-Meca, Julio: Universidad de Murcia, Murcia, Spain Rosa-Alcazar, Ana I.: Universidad de Murcia, Murcia, Spain Lopez-Soler, Concepcion: Universidad de Murcia, Murcia, Spain
AN  - 2010-26803-005
AU  - Sanchez-Meca,
AU  - J.
AU  - Rosa-Alcazar,
AU  - A.
AU  - I.
AU  - Lopez-Soler,
AU  - C.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0031967/
DP  - Ovid Technologies
KW  - psychological treatment, sexual abuse, age differences, children &amp; adolescents *Age Differences *Psychological Assessment *Sexual Abuse *Treatment *Victimization Child Abuse Behavior Disorders &amp; Antisocial Behavior [3230] Health &amp; Mental Health Treatmen
LA  - English
M3  - Meta Analysis
PY  - 2011
SP  - 67-93
T2  - International Journal of Clinical and Health Psychology
TI  - The psychological treatment of sexual abuse in children and adolescents: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2010-26803-005 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=1697-2600&amp;isbn=&amp;volume=11&amp;issue=1&amp;spage=67&amp;pages=67-93&amp;date=2011&amp;title=International+Journal+of+Clinical+and+Health+Psychology&amp;atitle=The+psychological+treatment+of+sexual+abuse+in+children+and+adolescents%3A+A+meta-analysis.&amp;aulast=Sanchez-Meca&amp;pid=%3Cauthor%3ESanchez-Meca%2C+Julio%3C%2Fauthor%3E%3CAN%3E2010-26803-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 11
ER  -
TY  - JOUR
AB  - **Objective: **
Evidence on effectiveness of combined treatments versus antidepressants alone in adolescents consists on a few studies in both major depressive and anxiety disorders. A meta-analysis of randomised 12-week follow-up studies in which antidepressant treatment was compared to combined treatment consisting of the same antidepressant with cognitive behavioural therapy has been performed. 

**Methods: **
Data were entered into the Cochrane Collaboration Review Manager software and were analysed within a random effect framework. A quality assessment has been performed through Jadad Scale. 

**Results: **
Higher global functioning at the Children&#039;s Global Assessment Scale was found in the combined treatment group (p &lt; 0.0001) as well as higher improvement at the Clinical Global Impressions Improvement Scale (p = 0.04). No benefit of combined treatment was found on depressive symptomatology at the Children&#039;s Depression Rating Scale-Revised. 

**Conclusion: **
Combined treatment seems to be more effective than antidepressant alone on global functioning and general improvement in adolescents with major depressive and anxiety disorders. 

(PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - Serretti, Alessandro: alessandro.serretti@unibo.it Serretti, Alessandro: Institute of Psychiatry, University of Bologna, Viale Carlo Pepoli 5, Bologna, Italy, 40123, alessandro.serretti@unibo.it Calati, Raffaella: Institute of Psychiatry, University of Bologna, Bologna, Italy Pedrini, Laura: IRCCS Centro S. Giovanni di Dio Fatebenefratelli, Brescia, Italy Alighieri, Sara: N.P.E.E., Rimini AUSL, Rimini, Italy Alvarez, Mariela Ivana: Children and Adolescent Psychiatry Unit, Reggio Emilia AUSL, Reggio Emilia, Italy Desideri, Lorenzo: Department of Mental Health, Children and Adolescent Psychiatry Unit, AUSL Bologna, Bologna, Italy Durante, Daniele: N.P.E.E., Parma AUSL, Parma, Italy Favero, Federica: Children and Adolescent Psychiatry Unit, Modena AUSL, Sassuolo, Italy Iero, Luisa: Child Neurology and Psychiatry Unit, Department of Neurological Sciences, University of Bologna, Bologna, Italy Magnani, Giulia: Department of Mental Health, Children and Adolescent Psychiatry Unit, AUSL Bologna, Bologna, Italy Pericoli, Valentina: Children and Adolescent Psychiatry Unit, Ravenna AUSL, Ravenna, Italy Polmonari, Alexia: Children and Adolescent Psychiatry Unit, Ferrara AUSL, Ferrara, Italy Raggini, Roberta: Children and Adolescent Psychiatry Unit, AUSL Forli, Forli, Italy Raimondi, Elena: Department of Mental Health, Children and Adolescent Psychiatry Unit, AUSL Bologna, Bologna, Italy Riboni, Valentina: Children and Adolescent Psychiatry Unit, Piacenza AUSL, Piacenza, Italy Scaduto, Maria Cristina: Child Neurology and Psychiatry Unit, Department of Neurological Sciences, University of Bologna, Bologna, Italy Serretti, Alessandro: Institute of Psychiatry, University of Bologna, Bologna, Italy De Girolamo, Giovanni: IRCCS Centro S. Giovanni di Dio Fatebenefratelli, Brescia, Italy
AN  - 2011-27788-003
AU  - Calati,
AU  - R.
AU  - Pedrini,
AU  - L.
AU  - Alighieri,
AU  - S.
AU  - Alvarez,
AU  - M.
AU  - I.
AU  - Desideri,
AU  - L.
AU  - Durante,
AU  - D.
AU  - Favero,
AU  - F.
AU  - Iero,
AU  - L.
AU  - Magnani,
AU  - G.
AU  - Pericoli,
AU  - V.
AU  - Polmonari,
AU  - A.
AU  - Raggini,
AU  - R.
AU  - Raimondi,
AU  - E.
AU  - Riboni,
AU  - V.
AU  - Scaduto,
AU  - M.
AU  - C.
AU  - Serretti,
AU  - A.
AU  - De
AU  - Girolamo,
AU  - G.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1601-5215.2011.00595.x
DP  - Ovid Technologies
KW  - cognitive behavioral therapy, antidepressants, adolescent development *Adolescent Development *Antidepressant Drugs *Cognitive Behavior Therapy Cognitive Therapy [3311] Human
LA  - English
M3  - Meta Analysis
PY  - 2011
SP  - 263-271
T2  - Acta Neuropsychiatrica
TI  - Is cognitive behavioural therapy an effective complement to antidepressants in adolescents? A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2011-27788-003 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1111%2Fj.1601-5215.2011.00595.x&amp;issn=0924-2708&amp;isbn=&amp;volume=23&amp;issue=6&amp;spage=263&amp;pages=263-271&amp;date=2011&amp;title=Acta+Neuropsychiatrica&amp;atitle=Is+cognitive+behavioural+therapy+an+effective+complement+to+antidepressants+in+adolescents%3F+A+meta-analysis.&amp;aulast=Calati&amp;pid=%3Cauthor%3ECalati%2C+Raffaella%3C%2Fauthor%3E%3CAN%3E2011-27788-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/doi/10.1111/j.1601-5215.2011.00595.x/abstracthttp://onlinelibrary.wiley.com/store/10.1111/j.1601-5215.2011.00595.x/asset/j.1601-5215.2011.00595.x.pdf?v=1&amp;t=ibbyvrj9&amp;s=cf162baf3874965b0854bb52cf566ef779072abb
UR  - https://www.cambridge.org/core/journals/acta-neuropsychiatrica/article/is-cognitive-behavioural-therapy-an-effective-complement-to-antidepressants-in-adolescents-a-metaanalysis/D897467A2F9BE1F17CFABF732D81B44F
VL  - 23
ER  -
TY  - JOUR
AB  - **Objective: **
This meta-analytic review assesses the effectiveness of substance abuse interventions to reduce adolescent cannabis use. 

**Method: **
A systematic search identified 15 randomized controlled evaluations of interventions to reduce adolescent cannabis use published between 1960 and 2008. The primary outcome variables, frequency of cannabis use, and quantity of cannabis use, were measured between 1 month and 1 year posttreatment completion.

**Results: **
Analyses of random effects models revealed similarly moderate effects for individual (g = -.437; 95% CI = [-.671, -.203]) and family-based treatments (g = -.404; 95% CI = [-.613, -.195]). Substance abuse treatments are associated with moderate reductions in cannabis use although effect sizes tended to wane with greater length of time posttreatment. 

**Discussion: **
Substance abuse treatment programs should consider implementing evidence-based interventions highlighted in this meta-analysis that fit the needs and characteristics of their client base and agency setting. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Bender, Kimberly: kimberly.bender@du.edu Bender, Kimberly, 2148 S. High Street, Denver, CO, US, 80208, kimberly.bender@du.edu Bender, Kimberly: Graduate School of Social Work, University of Denver, Denver, CO, US Tripodi, Stephen J.: College of Social Work, Florida State University, Tallahassee, FL, US Sarteschi, Christy: School of Social Work, University of Pittsburgh, Pittsburgh, PA, US Vaughn, Michael G.: Saint Louis University, School of Social Work, St. Louis, MO, US
AN  - 2011-03038-001
AU  - Bender,
AU  - K.
AU  - Tripodi,
AU  - S.
AU  - J.
AU  - Sarteschi,
AU  - C.
AU  - Vaughn,
AU  - M.
AU  - G.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1049731510380226
DP  - Ovid Technologies
KW  - intervention effectiveness, adolescent cannabis use, drug rehabilitation *Cannabis *Drug Rehabilitation *Intervention *Treatment Effectiveness Evaluation Adolescent Psychology Drug &amp; Alcohol Rehabilitation [3383] Human Adolescence (13-17 yrs)
LA  - English
M3  - Literature Review; Systematic Review; Meta Analysis
PY  - 2011
SP  - 153-164
T2  - Research on Social Work Practice
TI  - A meta-analysis of interventions to reduce adolescent cannabis use
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc8&amp;AN=2011-03038-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1049731510380226&amp;issn=1049-7315&amp;isbn=&amp;volume=21&amp;issue=2&amp;spage=153&amp;pages=153-164&amp;date=2011&amp;title=Research+on+Social+Work+Practice&amp;atitle=A+meta-analysis+of+interventions+to+reduce+adolescent+cannabis+use.&amp;aulast=Bender&amp;pid=%3Cauthor%3EBender%2C+Kimberly%3C%2Fauthor%3E%3CAN%3E2011-03038-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rsw.sagepub.com/content/21/2/153http://rsw.sagepub.com/content/21/2/153.full.pdf
VL  - 21
ER  -
TY  - JOUR
AB  - The present meta-analysis examined the effects of psychosocial treatments at reducing deleterious outcomes of sexual abuse. 

The meta-analysis included a total of 35 published and unpublished studies written in English, focusing on youth under the age of 18, and evaluating the effectiveness of treatments for the most common negative outcomes of sexual abuse: PTSD symptoms, externalizing problems, and internalizing problems. 
Results revealed medium effect sizes for PTSD symptoms, externalizing problems, and internalizing problems following treatment for sexual abuse. 

This study also examined the potential moderating effects of treatment (e.g., modality, duration, and inclusion of caregiver) and participant (e.g., age, gender, and ethnicity) characteristics. 

Results indicated that longer interventions were associated with greater treatment gains while group and individual treatments were equally effective. These findings shed new light on treatment effectiveness and provide useful information regarding the conditions under which treatment may be most effective. 

Future directions for research in this area are discussed. 

&copy; 2010 Elsevier Ltd.
AD  - (Trask, Walsh, DiLillo) University of Nebraska-Lincoln, 238 Burnett Hall, Lincoln, NE 68588-0308, United States E.V. Trask, Child and Adolescent Services Research Center, University of California, 3665 Kearney Villa Road, Ste 200, San Diego, CA 92123, United States. E-mail: evtrask@ucsd.edu
AN  - 2011097485
AU  - Trask,
AU  - E.
AU  - V.
AU  - Walsh,
AU  - K.
AU  - DiLillo,
AU  - D.
DA  - January-February
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.avb.2010.10.001
DP  - Ovid Technologies
KW  - Childhood sexual abuse Meta-analysis Quantitative review Treatment outcomes adolescent adult age distribution caregiver child child sexual abuse/th [Therapy] clinical effectiveness ethnicity female follow up human major clinical study male meta analysis
L1  - internal-pdf://3259967373/Trask-2011-Treatment effects for common outcom.pdf
LA  - English
M3  - Review
PY  - 2011
SP  - 6-19
T2  - Aggression and Violent Behavior
TI  - Treatment effects for common outcomes of child sexual abuse: A current meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed10&amp;AN=2011097485
UR  - http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1016%2Fj.avb.2010.10.001&amp;issn=1359-1789&amp;isbn=&amp;volume=16&amp;issue=1&amp;spage=6&amp;pages=6-19&amp;date=2011&amp;title=Aggression+and+Violent+Behavior&amp;atitle=Treatment+effects+for+common+outcomes+of+child+sexual+abuse%3A+A+current+meta-analysis&amp;aulast=Trask&amp;pid=%3Cauthor%3ETrask+E.V.%3C%2Fauthor%3E%3CAN%3E2011097485%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095890/pdf/nihms254267.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - A systematic review and meta-analysis were performed examining the efficacy of aripiprazole for the treatment of irritability associated with autistic disorder in children and adolescents. 

Aripiprazole was found to be more effective in reducing irritability compared with placebo at 8 weeks, SMD -0.64 [-0.90 to -0.39, P &lt; 0.00001] as determined by the Aberrant Behaviour Checklist irritability subscale (ABC-I). 

Pooled data from two eight week trials show that sedation is the most commonly reported adverse event. Statistically significant weight gain was also associated with aripiprazole, but there was a decrease in serum prolactin. 

Most adverse effects were deemed to be mild to moderate in severity. Four open trials and three case series all show support for aripiprazole in reducing the behavioural symptoms of autism. Long-term studies are required to determine the efficacy and safety of aripiprazole in autistic disorder in children.
AD  - Douglas-Hall,Petrina. Pharmacy Department, South London and Maudsley NHS Foundation Trust, Denmark Hill, London SE5 8AZ.
AN  - 23861644
AU  - Douglas-Hall,
AU  - P.
AU  - Curran,
AU  - S.
AU  - Bird,
AU  - V.
AU  - Taylor,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4137/jcnsd.s4140
DP  - Ovid Technologies
J2  - J
L1  - internal-pdf://1890329156/Douglas-Hall-2011-Aripiprazole_ a review of it.pdf
LA  - English
N1  - Douglas-Hall, Petrina Curran, Sarah Bird, Victoria Taylor, David
PY  - 2011
SP  - 143-53
T2  - Journal of Central Nervous System Disease
TI  - Aripiprazole: a review of its use in the treatment of irritability associated with autistic disorder patients aged 6-17
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=23861644
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:23861644&amp;id=doi:10.4137%2FJCNSD.S4140&amp;issn=1179-5735&amp;isbn=&amp;volume=3&amp;issue=&amp;spage=143&amp;pages=143-53&amp;date=2011&amp;title=Journal+of+Central+Nervous+System+Disease&amp;atitle=Aripiprazole%3A+a+review+of+its+use+in+the+treatment+of+irritability+associated+with+autistic+disorder+patients+aged+6-17.&amp;aulast=Douglas-Hall&amp;pid=%3Cauthor%3EDouglas-Hall+P%3C%2Fauthor%3E%3CAN%3E23861644%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.la-press.com/redirect_file.php?fileId=3638&amp;filename=2715-JCNSD-Aripiprazole:-A-Review-of-its-Use-in-the-Treatment-of-Irritability-Ass.pdf&amp;fileType=pdf
UR  - http://journals.sagepub.com/doi/pdf/10.4137/JCNSD.S4140
VL  - 3
ER  -
TY  - JOUR
AB  - The aim of this study was to systematically review the effectiveness of music on pediatric health-related outcomes. Five electronic databases were searched for randomized controlled/crossover trial designs published between 1984 and 2009. Eligible studies used music as a therapy or intervention, included participants 1 to 18 years, and focused on at least one health-related outcome (with the exclusion of procedural pain). 

Seventeen studies met the inclusion criteria. Quantitative synthesis was hampered by an inability to aggregate data arising from heterogeneity of interventions, outcomes and measurement tools. Qualitative synthesis revealed significant improvements in one or more health outcomes within four of seven trials involving children with learning and developmental disorders; two of three trials involving children experiencing stressful life events; and four of five trials involving children with acute and/or chronic physical illness. 

No significant effects were found for two trials involving children with mood disorders and related psychopathology. These findings offer limited qualitative evidence to support the effectiveness of music on health-related outcomes for children and adolescents with clinical diagnoses. 

Recommendations for establishing a consensus on research priorities and addressing methodological limitations are put forth to support the continued advancement of this popular intervention.
AD  - [Naylor, Karline Treurnicht; Kingsnorth, Shauna; Lamont, Andrea; McKeever, Patricia; Macarthur, Colin] Holland Bloorview Kids Rehabil Hosp, Bloorview Res Inst, Toronto, ON M4G 1R8, Canada. [Kingsnorth, Shauna; McKeever, Patricia] Univ Toronto, Lawrence S Bloomberg Fac Nursing, Toronto, ON M5T 1P8, Canada. [Kingsnorth, Shauna; Macarthur, Colin] Univ Toronto, Fac Med, Dept Paediat, Toronto, ON M5S 1A8, Canada. [Lamont, Andrea] Wilfrid Laurier Univ, Fac Mus, Dept Mus Therapy, Waterloo, ON N2L 3C5, Canada. Kingsnorth, S (reprint author), Holland Bloorview Kids Rehabil Hosp, Bloorview Res Inst, Toronto, ON M4G 1R8, Canada. skingsnorth@hollandbloorview.ca
AN  - WOS:000293461100001
AU  - Naylor,
AU  - K.
AU  - T.
AU  - Kingsnorth,
AU  - S.
AU  - Lamont,
AU  - A.
AU  - McKeever,
AU  - P.
AU  - Macarthur,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1155/2011/464759
J2  - Evid.-based Complement Altern. Med.
KW  - CONSORT STATEMENT PEDRO SCALE METHODOLOGICAL QUALITY PRISMA STATEMENT THERAPY CHILDREN METAANALYSIS ADOLESCENTS BEHAVIORS INTERVENTION Integrative &amp; Complementary Medicine
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 801SQ Times Cited: 1 Cited Reference Count: 74 Naylor, Karline Treurnicht Kingsnorth, Shauna Lamont, Andrea McKeever, Patricia Macarthur, Colin 1 HINDAWI PUBLISHING CORPORATION NEW YORK EVID-BASED COMPL ALT
PY  - 2011
SP  - 1-18
T2  - Evidence-Based Complementary and Alternative Medicine
TI  - The Effectiveness of Music in Pediatric Healthcare: A Systematic Review of Randomized Controlled Trials
UR  - &lt;Go to ISI&gt;://WOS:000293461100001http://downloads.hindawi.com/journals/ecam/2011/464759.pdf
ER  -
TY  - JOUR
AB  - This study sought to determine the effectiveness of culturally sensitive interventions (CSIs) in reducing high risk behaviors with African American youth. A meta-analysis was conducted to assess the effectiveness of CSIs across seven studies. African American youth who participated in CSIs were less likely to engage in high risk behaviors compared to those who did not participate. The effect size was moderate (g = .35). Although the findings should be considered tentative, the results provide an initial quantitative assessment of CSI effectiveness that future evaluations and meta-analyses can build upon as CSI research expands. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Jackson, Kelly F.: kelly.f.jackson@asu.edu Jackson, Kelly F.: Arizona State University, School of Social Work, 411 N. Central Ave, Suite 800, Phoenix, AZ, US, 85004-0689, kelly.f.jackson@asu.edu Jackson, Kelly F.: Arizona State University, School of Social Work, Phoenix, AZ, US Hodge, David R.: Arizona State University, School of Social Work, Phoenix, AZ, US Vaughn, Michael G.: Saint Louis University, School of Social Work, Division of Epidemiology, Department of Public Policy Studies, St. Louis, MO, US
AN  - 2010-16137-001
AU  - Jackson,
AU  - K.
AU  - F.
AU  - Hodge,
AU  - D.
AU  - R.
AU  - Vaughn,
AU  - M.
AU  - G.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/01488371003697780
DP  - Ovid Technologies
KW  - meta analysis, culturally sensitive interventions, high risk behaviors, African American *At Risk Populations *Blacks *Intervention *Risk Taking Meta Analysis Social Processes &amp; Social Issues [2900] Human Childhood (birth-12 yrs) Adolescence (13-17 yrs)
LA  - English
M3  - Meta Analysis
PY  - 2010
SP  - 163-173
T2  - Journal of Social Service Research
TI  - A meta-analysis of culturally sensitive interventions designed to reduce high-risk behaviors among African American youth
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc7&amp;AN=2010-16137-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F01488371003697780&amp;issn=0148-8376&amp;isbn=&amp;volume=36&amp;issue=3&amp;spage=163&amp;pages=163-173&amp;date=2010&amp;title=Journal+of+Social+Service+Research&amp;atitle=A+meta-analysis+of+culturally+sensitive+interventions+designed+to+reduce+high-risk+behaviors+among+African+American+youth.&amp;aulast=Jackson&amp;pid=%3Cauthor%3EJackson%2C+Kelly+F%3C%2Fauthor%3E%3CAN%3E2010-16137-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/01488371003697780
VL  - 36
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
To review the impact of polyunsaturated fatty acids (PUFA) in reducing ADHD symptoms in children. 

**METHODS: **
Peer-reviewed experimental literature published from 1980 to Mai 2009 is consulted (Psychinfo, Medline, and resulting reference lists). 

**RESULTS:**
Placebo-controlled studies with ADHD or hyperactive children show no effects on behaviors or cognition when only n-6 (omega-6) PUFA, only docosahexaenoic acid (DHA), or n-6 and n-3 (omega-3) short-chain PUFA are supplemented. Yet three out of four studies suggest that a combination of long-chain n-3 and n-6 fatty acids (DHA, eicosapentaenoic acid [EPA], and gamma-linolenic acid [GLA]) supplemented daily for 3 to 4 months could lead to a reduction in ADHD symptomatology. Results on cognitive outcomes are inconsistent. 

**CONCLUSIONS: **
Evidence is too limited to reach definitive conclusions but suggests that research on the impact of long-chain PUFA (n-3 and n-6) should continue with special focus on individual differences (genetic and fatty acid markers), mechanisms (brain imaging), and new enhanced methods of systematic observations of behaviors.
AD  - Transler,Catherine. Unilever Food and Health Research Institute, the Netherlands. catherine.transler@unilever.com
AN  - 20424008
AU  - C.
AU  - Transler
AU  - A.
AU  - Eilander
AU  - S.
AU  - Mitchell
AU  - N.
AU  - van
AU  - de
AU  - Meer
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1087054709347250
DP  - Ovid Technologies
J2  - J Atten Disord
KW  - *Attention Deficit Disorder with Hyperactivity/dh [Diet Therapy] Child Clinical Trials as Topic *Dietary Supplements *Fatty Acids, Unsaturated/tu [Therapeutic Use] Humans Treatment Outcome 0 (Fatty Acids, Unsaturated)
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Transler, Catherine Eilander, Ans Mitchell, Siobhan van de Meer, Nelly
PY  - 2010
SP  - 232-46
T2  - Journal of Attention Disorders
TI  - The impact of polyunsaturated fatty acids in reducing child attention deficit and hyperactivity disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=20424008 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20424008&amp;id=doi:10.1177%2F1087054709347250&amp;issn=1087-0547&amp;isbn=&amp;volume=14&amp;issue=3&amp;spage=232&amp;pages=232-46&amp;date=2010&amp;title=Journal+of+Attention+Disorders&amp;atitle=The+impact+of+polyunsaturated+fatty+acids+in+reducing+child+attention+deficit+and+hyperactivity+disorders.&amp;aulast=Transler&amp;pid=%3Cauthor%3ETransler+C%3C%2Fauthor%3E%3CAN%3E20424008%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://jad.sagepub.com/content/14/3/232http://jad.sagepub.com/content/14/3/232.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/1087054709347250?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 14
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The treatment of adolescent depression is controversial and studies of combined treatment (antidepressants and cognitive-behavioural therapy, CBT) have produced conflicting findings. AIMS: To address the question of whether CBT confers additional benefit to antidepressant treatment in adolescents with unipolar depression for depressive symptoms, suicidality, impairment and global improvement. 

**METHOD: **
Meta-analysis of randomised controlled trials (RCTs) of newer-generation antidepressants and CBT in adolescent depression. 

**RESULTS: **
There was no evidence of a statistically significant benefit of combined treatment over antidepressants for depressive symptoms, suicidality and global improvement after acute treatment or at follow-up. There was a statistically significant advantage of combined treatment for impairment in the short-term (at 12 weeks) only. There was some evidence of heterogeneity between studies. 

**CONCLUSIONS: **
Adding CBT to antidepressants confers limited advantage for the treatment of an episode of depression in adolescents. The variation in sampling and methodology between studies, as well as the small number of trials, limits the generalisability of the findings and any conclusions that can be drawn. Future studies should examine predictors of response to treatment as well as clinical components that may affect outcome.
AD  - Dubicka,Bernadka. Lancashire Care Foundation Trust and Psychiatry Research Group, School of Community Based Medicine, University of Manchester, UK. Bernadka.Dubicka@manchester.ac.uk
AN  - 21119148
AU  - Dubicka,
AU  - B.
AU  - ElvinsR.
AU  - Roberts,
AU  - C.
AU  - Chick,
AU  - G.
AU  - Wilkinson,
AU  - P.
AU  - Goodyer,
AU  - I.
AU  - M.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1192/bjp.bp.109.075853
DP  - Ovid Technologies
J2  - Br J Psychiatry
KW  - Adolescent Child *Cognitive Therapy Combined Modality Therapy/mt [Methods] *Depressive Disorder/th [Therapy] Female Humans Male Practice Guidelines as Topic Psychiatric Status Rating Scales Randomized Controlled Trials as Topic *Serotonin Uptake Inhibit
L1  - internal-pdf://4246520412/Dubicka-2010-Combined treatment with cognitive.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Dubicka, Bernadka Elvins, Rachel Roberts, Chris Chick, Greg Wilkinson, Paul Goodyer, Ian M
PY  - 2010
SP  - 433-40
T2  - British Journal of Psychiatry
TI  - Combined treatment with cognitive-behavioural therapy in adolescent depression: meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=21119148 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21119148&amp;id=doi:10.1192%2Fbjp.bp.109.075853&amp;issn=0007-1250&amp;isbn=&amp;volume=197&amp;issue=6&amp;spage=433&amp;pages=433-40&amp;date=2010&amp;title=British+Journal+of+Psychiatry&amp;atitle=Combined+treatment+with+cognitive-behavioural+therapy+in+adolescent+depression%3A+meta-analysis.&amp;aulast=Dubicka&amp;pid=%3Cauthor%3EDubicka+B%3C%2Fauthor%3E%3CAN%3E21119148%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://bjp.rcpsych.org/content/bjprcpsych/197/6/433.full.pdf
UR  - http://bjp.rcpsych.org/content/bjprcpsych/197/6/433.full.pdf
VL  - 197
ER  -
TY  - JOUR
AB  - This paper presents a meta-analysis of the psychotherapy treatment outcome studies for sexually abused children and adolescents. There were 39 studies included, most of which aimed to treat the psychological effects of childhood sexual abuse. Separate meta-analyses were conducted according to study design and outcome domain, in keeping with meta-analytic conventions. However, given heterogeneity across studies and the need for sufficient n in each category for meaningful moderator analyses, the study designs were pooled into a repeated measures meta-analysis. There were large effect sizes for global outcomes (g = 1.37) and PTSD/trauma outcomes (g = 1.12). More moderate effect sizes were evident for internalizing symptoms (g = 0.74), self-appraisal (g = 0.63), externalizing symptoms (g = 0.52), and sexualized behavior (g = 0.49), while small effects were found for measures of coping/functioning (g = 0.44), caregiver outcomes (g = 0.43), and social skills/competence (g = 0.38). Effects were maintained at follow-up more than six months after treatment for some outcome domains but not others. Studies represented diverse treatment approaches, and most treatments were effective in symptom reduction. Presence of probable moderators of treatment outcome varied across symptom domains, reflecting importance of targeting therapy to individual needs. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Harvey, Shane T.: S.T.Harvey@massey.ac.nz; Taylor, Joanne E.: J.E.Taylor@massey.ac.nz Taylor, Joanne E.: School of Psychology, Massey University, Private Bag 11-222, Palmerston North, New Zealand, J.E.Taylor@massey.ac.nz Harvey, Shane T.: School of Psychology, Massey University, Palmerston North, New Zealand Taylor, Joanne E.: School of Psychology, Massey University, Palmerston North, New Zealand
AN  - 2010-08252-001
AU  - Harvey,
AU  - S.
AU  - Taylor,
AU  - J.
AU  - E.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2010.03.006
DP  - Ovid Technologies
KW  - psychotherapy, treatment outcomes, sexual abuse, childhood, adolescence *Adolescent Psychotherapy *Child Psychotherapy *Sexual Abuse *Treatment Outcomes Psychotherapy &amp; Psychotherapeutic Counseling [3310] Human Childhood (birth-12 yrs) Adolescence (13-1
LA  - English
M3  - Meta Analysis
PY  - 2010
SP  - 517-535
T2  - Clinical Psychology Review
TI  - A meta-analysis of the effects of psychotherapy with sexually abused children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc7&amp;AN=2010-08252-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.cpr.2010.03.006&amp;issn=0272-7358&amp;isbn=&amp;volume=30&amp;issue=5&amp;spage=517&amp;pages=517-535&amp;date=2010&amp;title=Clinical+Psychology+Review&amp;atitle=A+meta-analysis+of+the+effects+of+psychotherapy+with+sexually+abused+children+and+adolescents.&amp;aulast=Harvey&amp;pid=%3Cauthor%3EHarvey%2C+Shane+T%3C%2Fauthor%3E%3CAN%3E2010-08252-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735810000462/1-s2.0-S0272735810000462-main.pdf?_tid=747b5692-1972-11e5-b28f-00000aab0f01&amp;acdnat=1435041687_1d43c84f0e27bd16f0c259a51dfb497f
VL  - 30
ER  -
TY  - JOUR
AB  - The Daily Behavior Report Card is an intervention showing promise in various formats and in multiple settings. A meta-analysis evaluated the size of effects obtained from Daily Behavior Report Card interventions within single case research designs, investigating six potential moderators of treatment effects: student age, target behavior, home/school collaboration, breadth of use, scale construction, and reliability measure. Effect sizes are based on the improvement rate difference, a new overlap-based summary. Overall, data yielded 48 separate effect sizes from 17 studies. The mean improvement rate difference for all studies was 0.61 with a range of -0.15 to 0.97. This wide range of scores highlights the need to consider specific aspects of implementation to improve outcomes. High levels of home involvement and broad use throughout the day are associated with stronger intervention outcomes. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Vannest, Kimberly J.: kvannest@tamu.edu Vannest, Kimberly J.: Texas A&amp;M University, Department of Educational Psychology, MS 4225, College Station, TX, US, 77845, kvannest@tamu.edu Vannest, Kimberly J.: Department of Educational Psychology, Special Education Program, Texas A&amp;M University, College Station, TX, US Davis, John L.: School Psychology program, Texas A&amp;M University, College Station, TX, US Davis, Cole R.: School Psychology Program, Texas A&amp;M University, College Station, TX, US Mason, Benjamin A.: Texas A&amp;M University, College Station, TX, US Burke, Mack D.: Department of Educational Psychology, Special Education Program, Texas A&amp;M University, College Station, TX, US
AN  - 2011-00267-011
AU  - Vannest,
AU  - K.
AU  - J.
AU  - Davis,
AU  - J.
AU  - L.
AU  - Davis,
AU  - C.
AU  - R.
AU  - Mason,
AU  - B.
AU  - A.
AU  - Burke,
AU  - M.
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Har ikke DOI: https://eric.ed.gov/
DP  - Ovid Technologies
KW  - daily behavior report card intervention, student characteristic, student behavior, test validity, test reliability, psychometrics *Psychometrics *School Based Intervention *Student Characteristics *Student Records *Test Reliability Daily Activities Scho
LA  - English
M3  - Meta Analysis
PY  - 2010
SP  - 654-672
T2  - School Psychology Review
TI  - Effective intervention for behavior with a daily behavior report card: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc7&amp;AN=2011-00267-011 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=0279-6015&amp;isbn=&amp;volume=39&amp;issue=4&amp;spage=654&amp;pages=654-672&amp;date=2010&amp;title=School+Psychology+Review&amp;atitle=Effective+intervention+for+behavior+with+a+daily+behavior+report+card%3A+A+meta-analysis.&amp;aulast=Vannest&amp;pid=%3Cauthor%3EVannest%2C+Kimberly+J%3C%2Fauthor%3E%3CAN%3E2011-00267-011%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 39
ER  -
TY  - JOUR
AB  - **Background:** 
Neonatal abstinence syndrome (NAS) due to opiate withdrawal may result in disruption of the mother-infant relationship, sleep-wake abnormalities, feeding difficulties, weight loss and seizures. Treatments used to ameliorate symptoms and reduce morbidity include opiates, sedatives and non-pharmacological treatments.

**Objectives:** 
To assess the effectiveness and safety of using a sedative compared to a non-opiate control for NAS due to withdrawal from opiates, and to determine which type of sedative is most effective and safe.

**Search methods:** 
This update included searches of the Cochrane Central Register of Controlled Trials (Issue 1, 2010), MEDLINE 1966 to April 2010 and abstracts of conference proceedings.

**Selection criteria:** 
Trials enrolling infants with NAS born to mothers with an opiate dependence with &gt; 80% follow-up and using random or quasi-random allocation to sedative or control. Control could include another sedative or non-pharmacological treatment.

**Data collection and analysis:** 
Each author assessed study quality and extracted data independently.

**Main results:** 
Seven studies enrolling 385 patients were included. There were substantial methodological concerns for most studies including the use of quasi-random allocation methods and sizeable, largely unexplained differences in reported numbers allocated to each group.One study reported phenobarbitone compared to supportive care alone did not reduce treatment failure or time to regain birthweight, but resulted in a significant reduction in duration of supportive care (MD -162.1 min/day, 95% CI -249.2, -75.1). Comparing phenobarbitone to diazepam, meta-analysis of two studies found phenobarbitone resulted in a significant reduction in treatment failure (typical RR 0.39, 95% CI 0.24, 0.62). Comparing phenobarbitone with chlorpromazine, one study reported no significant difference in treatment failure.In infants treated with an opiate, one study reported addition of clonidine resulted in no significant difference in treatment failure, seizures or mortality. In infants treated with an opiate, one study reported addition of phenobarbitone significantly reduced the proportion of time infants had a high abstinence severity score, duration of hospitalisation and maximal daily dose of opiate.

**Authors&#039; conclusions:** 
Infants with NAS due to opiate withdrawal should receive initial treatment with an opiate. Where a sedative is used, phenobarbitone should be used in preference to diazepam. In infants treated with an opiate, the addition of phenobarbitone or clonidine may reduce withdrawal severity. Further studies are needed to determine the role of sedatives in infants with NAS due to opiate withdrawal and the safety and efficacy of adding phenobarbitone or clonidine in infants treated with an opiate for NAS.
AN  - CD002053
AU  - Osborn,
AU  - D.
AU  - A.
AU  - Jeffery,
AU  - H.
AU  - E.
AU  - Cole,
AU  - M.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd002053.pub3
KW  - Chlorpromazine [therapeutic use]
KW  - Clonidine [therapeutic use]
KW  - Diazepam [therapeutic use]
KW  - Hypnotics and Sedatives [therapeutic use]
KW  - Narcotics [therapeutic use]
KW  - Neonatal Abstinence Syndrome [drug therapy]
KW  - Opioid-Related Disorders [drug therapy]
KW  - Phenobarbital [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Humans[checkword]
KW  - Infant, Newborn[checkword]
KW  - Neonatal
PY  - 2010
T2  - Cochrane Database of Systematic Reviews
TI  - Sedatives for opiate withdrawal in newborn infants
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002053.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD002053.pub3/asset/CD002053.pdf?v=1&amp;t=iw7l4kss&amp;s=0e145fdb00e3baf28d5a64c5669ac44773f99546
ER  -
TY  - JOUR
AB  - -
AN  - 27820567
AU  - Moola,
AU  - S.
AU  - Pearson,
AU  - A.
AU  - Hagger,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.11124/01938924-201109180-00001
DP  - Ovid Technologies
J2  - JBI Libr Syst Rev
L1  - internal-pdf://4225401452/Anonymous-2010-Effectiveness of music interven.pdf
LA  - English
N1  - 01938924-201008161-00009
PY  - 2010
SP  - 1-14
T2  - JBI Library of Systematic Reviewis
TI  - Effectiveness of music interventions on dental anxiety in paediatric and adult patients-A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27820567http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27820567&amp;id=doi:&amp;issn=1838-2142&amp;isbn=&amp;volume=8&amp;issue=16&amp;spage=1&amp;pages=1-14&amp;date=2010&amp;title=JBI+Library+of+Systematic+Reviewis&amp;atitle=Effectiveness+of+music+interventions+on+dental+anxiety+in+paediatric+and+adult+patients-A+Systematic+Review.&amp;aulast=&amp;pid=%3Cauthor%3Eanonymous%3C%2Fauthor%3E%3CAN%3E27820567%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 8
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To examine duration of efficacy in long-acting stimulant treatment of attention-deficit/hyperactivity disorder (ADHD) in clinical trials using analog classroom protocols. 

**RESEARCH DESIGN AND METHODS:**
Published reports of clinical trials examining duration of medication efficacy using analog classroom protocols were identified in a systematic literature search of PubMed, BIOSYS, and EMBASE, through June 2009 using combinations of terms: attention-deficit/hyperactivity disorder, ADHD, attention-deficit disorder with hyperactivity, stimulant, methylphenidate (MPH), amphetamine, laboratory school or classroom, analog classroom, math test, and Permanent Product Measure of Performance (PERMP). Reports of short-acting, nonoral or nonstimulant formulations, or inadequate data on duration of efficacy were excluded. 

**MAIN OUTCOME MEASURES: **
Main outcomes examined were PERMP scores for number of math problems attempted (PERMP-A) and correctly answered (PERMP-C) based on a standard 10-minute math test given at regular intervals during the postdose period. 

**RESULTS: **
Fifteen trials were included in the analysis. All except one trial in adults (18-55 years) were conducted in children with ADHD (6-15 years) and employed randomized, double- or single-blind, placebo-controlled designs. Duration of efficacy, based on PERMP-A/-C scores (vs. placebo), ranged from 8 hours with long-acting MPH to 14 hours with lisdexamfetamine dimesylate; most formulations exerted therapeutic effects for 12 hours after a single morning dose. Duration of efficacy assessment may be limited by duration of observation (12 hours postdose for most studies). Outcomes may have been influenced by differences in study designs, population characteristics, lack of comparable, equivalent dosages of different extended-release stimulants, and limited ability to extrapolate safety and tolerability from short-term studies to long-term clinical use. Results from cross-study comparisons must be interpreted with caution. 

**CONCLUSIONS: **
Most long-acting stimulants exerted beneficial effects on ADHD symptoms for up to 12 hours as measured by the PERMP; the longest duration of efficacy versus placebo was seen with lisdexamfetamine dimesylate (14 hours postdose).
AD  - Brams,Matthew. Baylor College of Medicine, Houston, TX, USA. drmattbrams@aol.com
AN  - 20491612
AU  - Brams,
AU  - M.
AU  - Moon,
AU  - E.
AU  - Pucci,
AU  - M.
AU  - Lopez,
AU  - F.
AU  - A.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1185/03007995.2010.488553
DP  - Ovid Technologies
J2  - Curr Med Res Opin
KW  - Administration, Oral *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] *Central Nervous System Stimulants/ad [Administration &amp; Dosage] Clinical Trials as Topic *Dextroamphetamine/ad [Administration &amp; Dosage] Drug Administration Schedule H
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Brams, Matthew Moon, Eliot Pucci, Michael Lopez, Frank A
PY  - 2010
SP  - 1809-25
T2  - Current Medical Research &amp; Opinion
TI  - Duration of effect of oral long-acting stimulant medications for ADHD throughout the day
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=20491612 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20491612&amp;id=doi:10.1185%2F03007995.2010.488553&amp;issn=0300-7995&amp;isbn=&amp;volume=26&amp;issue=8&amp;spage=1809&amp;pages=1809-25&amp;date=2010&amp;title=Current+Medical+Research+%26+Opinion&amp;atitle=Duration+of+effect+of+oral+long-acting+stimulant+medications+for+ADHD+throughout+the+day.&amp;aulast=Brams&amp;pid=%3Cauthor%3EBrams+M%3C%2Fauthor%3E%3CAN%3E20491612%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://informahealthcare.com/doi/pdfplus/10.1185/03007995.2010.488553
VL  - 26
ER  -
TY  - JOUR
AB  - **AIM **
The purpose of this systematic review was to examine the quality of conduct of experimental studies contributing to our empirical understanding of function-based behavioural interventions for stereotypic and repetitive behaviours (SRBs) in individuals with autism spectrum disorders (ASDs). 

**METHOD **
Systematic review methodology was used to identify relevant articles, to rate the level of evidence and quality of conduct of the studies, and to extract data systematically. 

**RESULTS**
Ten single case studies examining 17 participants (14 males, 3 females; age 2y 11mo-26y) diagnosed with various ASDs were included. Overall, studies reported decreases in SRBs using behavioural interventions and some collateral increase in desirable behaviours. 

**INTERPRETATION** 
Only a small number of intervention studies for SRBs explicitly state the function of the behaviour; therefore, relatively little is known about the efficacy of SRB interventions in relation to the range of possible behavioural functions. Evidence supporting SRB interventions is preliminary in nature, and caution should be used in choosing and implementing SRB intervention practices for individuals with ASDs.
AD  - [Patterson, Stephanie Y.; Smith, Veronica; Jelen, Michaela] Univ Alberta, Dept Educ Psychol, Fac Educ, Edmonton, AB T6G 2G5, Canada. Patterson, SY (reprint author), Univ Alberta, Dept Educ Psychol, Fac Educ, 6-123F Educ N, Edmonton, AB T6G 2G5, Canada. syp1@ualberta.ca
AN  - WOS:000275205100005
AU  - Patterson,
AU  - S.
AU  - Y.
AU  - Smith,
AU  - V.
AU  - Jelen,
AU  - M.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1469-8749.2009.03597.x
J2  - Dev. Med. Child Neurol.
KW  - SINGLE-SUBJECT RESEARCH NONCONTINGENT REINFORCEMENT PSYCHOSOCIAL INTERVENTIONS RESPONSE BLOCKING CHILDREN STIMULATION METHODOLOGY VALIDATION EFFICACY Clinical Neurology Pediatrics
L1  - internal-pdf://3523146896/Patterson-2010-Behavioural intervention practi.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 564HY Times Cited: 8 Cited Reference Count: 52 Patterson, Stephanie Y. Smith, Veronica Jelen, Michaela 8 WILEY-BLACKWELL PUBLISHING, INC MALDEN DEV MED CHILD NEUROL
PY  - 2010
SP  - 318-327
T2  - Developmental Medicine and Child Neurology
TI  - Behavioural intervention practices for stereotypic and repetitive behaviour in individuals with autism spectrum disorder: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000275205100005http://onlinelibrary.wiley.com/store/10.1111/j.1469-8749.2009.03597.x/asset/j.1469-8749.2009.03597.x.pdf?v=1&amp;t=ib7vbc4i&amp;s=6606002c839015a49daa1a1d646d65cbe5eef26e
UR  - http://onlinelibrary.wiley.com/store/10.1111/j.1469-8749.2009.03597.x/asset/j.1469-8749.2009.03597.x.pdf?v=1&amp;t=j8yg328i&amp;s=c7bf5821d55243ad3d8832c4a05e5f3fba55a07b
VL  - 52
ER  -
TY  - JOUR
AB  - **Objectives:** 
The main objective of this review is to assess the available research evidence on the effect of self-control improvement programs on self-control and delinquency and problem behaviors. In addition to investigating the overall effect of early selfcontrol improvement programs, this review will examine, to the extent possible, the context in which these programs may be most successful. 

**Search strategy:** 
Several strategies were used to perform an exhaustive search for literature fitting the eligibility criteria: (1) A keyword search was conducted across a number of online abstract databases; (2) The reference lists of previous reviews of early childhood prevention/intervention programs in general and self-control improvement programs specifically were consulted; (3) Hand searches were carried out on leading journals in the field; (4) The publications of research and professional agencies were searched; and (5) Recognized scholars (experts) in various disciplines who were knowledgeable in the specific area of self-control improvement programs were contacted. 

**Selection criteria:** 
Studies that investigated the effect of early self-control improvement programs on improving self-control, and/or reducing delinquency and problem behaviors were included. Studies were only included if they had a randomized controlled evaluation design that provided post-test measures of self-control and/or delinquency and problem behaviors among experimental and control subjects. 

**Data collection and analysis:** 
Narrative findings are reported for the 34 studies included in this review. A metaanalysis of all 34 of these studies was carried out. The means and standard deviations were predominantly used to measure the effect size. Results are reported for the unbiased effect sizes and the weighted effect sizes and, where possible, comparisons across outcome sources (parent-reports, teacher-reports, directobserver reports, self-reports, and clinical reports). Bivariate and multivariate analyses (using Lipsey &amp;Wilson&#039;s SPSS macros) are performed in an effort to determine potential moderators and predictors of the effect sizes, respectively. 

**Main results:** 
The studies included in this systematic review indicate that self-control improvement programs are an effective intervention for improving self-control and reducing delinquency and problem behaviors, and that the effect of these programs appears to be rather robust across various weighting procedures, and across context, outcome source, and based on both published and unpublished data. 

**Authors&#039; conclusions:**
We conclude that self-control improvement programs should continue to be used to improve self-control and reduce delinquency and behavior problems up to age 10, which is the age cutoff where Gottfredson and Hirschi argue that self-control becomes relatively fixed and no longer malleable. Considering these results, future efforts should be made to examine the effectiveness of self-control improvement programs over time and across different segments of the life-course (e.g., midadolescence, young adulthood etc.), and conduct rigorous cost-benefit analysis on programs such as these.
AU  - Piquero,
AU  - A.
AU  - R.
AU  - Jennings,
AU  - W.
AU  - Farrington,
AU  - D.
AU  - Jennings,
AU  - W.
AU  - G.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2010.2
PY  - 2010
T2  - Campbell Systematic Reviews
TI  - Self-Control Interventions for Children Under Age 10 for Improving Self-Control and Delinquency and Problem Behaviors
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To evaluate the efficacy and safety of melatonin for the treatment of insomnia in pediatric patients with attention-deficit/hyperactivity disorder (ADHD). 

**DATA SOURCES:** 
Literature was accessed through MEDLINE (1948-August 2009), EMBASE (1950-August 2009), and Scopus (1960-August 2009) using the terms melatonin, attention-deficit/hyperactivity disorder (ADHD), pediatric, insomnia, sleep disorder, and sleep. In addition, reference citations from publications identified were reviewed for relevant information. 

**STUDY SELECTION AND DATA EXTRACTION: **
All English-language articles and human studies were identified and evaluated. Results from all identified randomized trials (n = 5), safety studies (n = 1), long-term follow-up studies (n = 1), post hoc retrospective analyses (n = 1), meta-analyses (n = 2), review articles (n = 9), and letters (n = 1) were summarized. 

**DATA SYNTHESIS: **
Pediatric insomnia is prevalent in children with ADHD and impacts academic performance, social functioning, overall health, and family life. First-line therapy includes ruling out differential diagnoses, optimizing ADHD stimulant treatment, and initiating good sleep hygiene and behavioral therapy. Adjuvant pharmacotherapy is then an option and melatonin is often prescribed. Melatonin regulates circadian rhythm sleep disorders such as sleep-onset insomnia (SOI) in children with ADHD. Four studies in children with ADHD and insomnia showed improvement in sleep onset and sleep latency. Studies included children 6-14 years old and melatonin doses ranged from 3 to 6 mg administered within a few hours of a scheduled bedtime. In all studies, adverse events were transient and mild. The available melatonin studies are limited by small size and short duration; variable SOI criteria, ADHD criteria, and treatment assessments; and lack of generalizability. 

**CONCLUSIONS: **
Available data suggest that melatonin is a well-tolerated and efficacious treatment option for pediatric patients with chronic SOI and ADHD. Regulated melatonin products and larger, well-designed trials to establish optimal dosing regimens and long-term safety are needed.
AD  - Bendz,Lisa M. Department of Pharmacy, Duke University Hospital, Durham, NC, USA. isa.m.bendz@gsk.com
AN  - 20028959
AU  - Bendz,
AU  - L.
AU  - M.
AU  - Scates,
AU  - A.
AU  - C.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1345/aph.1M365
DP  - Ovid Technologies
J2  - Ann Pharmacother
KW  - *Attention Deficit Disorder with Hyperactivity/co [Complications] Child Humans *Melatonin/tu [Therapeutic Use] Sleep Initiation and Maintenance Disorders/co [Complications] *Sleep Initiation and Maintenance Disorders/dt [Drug Therapy] JL5DK93RCL (Melato
LA  - English
M3  - Review
N1  - Bendz, Lisa M Scates, Ann C
PY  - 2010
SP  - 185-91
T2  - Annals of Pharmacotherapy
TI  - Melatonin treatment for insomnia in pediatric patients with attention-deficit/hyperactivity disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=20028959 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20028959&amp;id=doi:10.1345%2Faph.1M365&amp;issn=1060-0280&amp;isbn=&amp;volume=44&amp;issue=1&amp;spage=185&amp;pages=185-91&amp;date=2010&amp;title=Annals+of+Pharmacotherapy&amp;atitle=Melatonin+treatment+for+insomnia+in+pediatric+patients+with+attention-deficit%2Fhyperactivity+disorder.&amp;aulast=Bendz&amp;pid=%3Cauthor%3EBendz+LM%3C%2Fauthor%3E%3CAN%3E20028959%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://aop.sagepub.com/content/44/1/185http://aop.sagepub.com/content/44/1/185.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1345/aph.1M365?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 44
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Nocturnal enuresis is the involuntary loss of urine at night in a child of an age and physical health where they would be expected to be dry. The prevalence of this condition in Australia has been estimated at 18.9% in children 5 to 12 years of age, with up to 19% of boys and 16% of girls aged 5 years wetting the bed at least once per month. Up to the age of 13 years bedwetting is more common in boys and more common in girls after this age. Nocturnal enuresis has a spontaneous cure rate of approximately 14% however up to 3% of children remain enuretic as adults. Although this condition is pathologically benign, it can have serious social and psychological repercussions for the sufferer including affects on self esteem, school success, parental disapproval and even sexual activity in later life. Despite the volume of information available for the management of enuresis, the majority of research has been conducted outside Australia. Therefore, the purpose of this work was to produce management guidelines for nocturnal enuresis in children specific to Australian clinical practice. 

**INCLUSION CRITERIA: **
This review considered systematic reviews or concurrently controlled trials (randomised controlled trials (RCT), pseudo-randomised controlled trials, controlled clinical trials (CCT), interrupted time series (ITS) and controlled before and after trials (CBA)), for examining effectiveness of interventions to manage nocturnal enuresis in children up to the age of 16 years. 

**SEARCH STRATEGY: **
A systematic search of the literature was performed to identify all available evidence. Cochrane and other health technology assessment websites were searched for existing systematic reviews. For recent randomised controlled trials and controlled trials (1990 to 2007) Pubmed, Embase, and CINAHL databases were searched. Reference lists of all retrieved articles were searched for relevant trials. These reviews and guidelines were summarised and presented to an advisory panel of nurse continence advisors and clinicians to ensure relevance to Australian clinical practice. 

**METHODOLOGICAL QUALITY: **
Methodological quality of all studies was assessed by two reviewers using the JBI critical appraisal forms for experimental studies located within the JBI-MAStARI software. This tool was used to identify all sources of bias. Where disagreement existed between the two reviewers a third reviewer adjudicated. 

**RESULTS: **
Seven systematic reviews, eight new trials and two guidelines were used in the development of these guidelines.Briefly management recommendations include: 

**CONCLUSIONS:**
Despite the high prevalence of nocturnal enuresis and the negative psychosocial sequelae that can arise from this condition, management is both readily available and effective. 

**IMPLICATIONS FOR PRACTICE: **
The practice of managing nocturnal enuresis in children should start with addressing both daytime wetting and any evidence of constipation. Following this, less invasive behavioural therapies should be attempted. If these measures fail then the use of alarms with or without short-term administration of desmopressin could be attempted. Other interventions have yet to be proven to be definitively effective and should be considered with caution.It should be emphasized however, that the vast majority of children will become continent at some future time point, with or without the benefit of interventions. 

**IMPLICATIONS FOR RESEARCH:**
While it is clear that some behavioural methods, alarms and desmopressin can be effective interventions, the evidence for other treatments is not so definitive. The observation however that even alarms and/or desmopressin do not work for all children suggests that research to establish the effectiveness of other interventions (especially behavioural and complementary treatments) should be performed in the form of large, carefully designed RCTs.
AD  - Hodgkinson, Brent. 1. Senior Business Improvement Officer, Organisational Development Group, Blue Care 2. Clinical Researcher (Continence), UQ/ Blue Care Research and Practice Development Centre &amp; Continence Advisor Blue Care. 3. Professor and Director of Research, Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore.
AN  - 27819861
AU  - Hodgkinson,
AU  - B.
AU  - Josephs,
AU  - K.
AU  - Hegney,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.11124/01938924-201008050-00001
DP  - Ovid Technologies
J2  - JBI Libr Syst Rev
L1  - internal-pdf://3759081026/Hodgkinson-2010-Best practice in the managemen.pdf
LA  - English
N1  - Hodgkinson, Brent Josephs, Kay Hegney, Desley 01938924-201008050-00001
PY  - 2010
SP  - 173-254
T2  - JBI Library of Systematic Reviewis
TI  - Best practice in the management of primary nocturnal enuresis in children: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27819861http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27819861&amp;id=doi:&amp;issn=1838-2142&amp;isbn=&amp;volume=8&amp;issue=5&amp;spage=173&amp;pages=173-254&amp;date=2010&amp;title=JBI+Library+of+Systematic+Reviewis&amp;atitle=Best+practice+in+the+management+of+primary+nocturnal+enuresis+in+children%3A+a+systematic+review.&amp;aulast=Hodgkinson&amp;pid=%3Cauthor%3EHodgkinson+B%3C%2Fauthor%3E%3CAN%3E27819861%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 8
ER  -
TY  - JOUR
AB  - This review examines the use of a cognitive-behavioural approach to anger management in children with special needs in community settings. 

Eighteen experimental studies involving a total of 408 children were located. The participants were mainly of high school age, with an IQ above 80, and with behavioural or emotional disorders. 

A moderate effect was observed for improvement in the three dimensions of anger: behaviour, cognition and emotion-although conclusions need to be very tentative. 

The interventions employed varied greatly in their characteristics and there were concerns about the quality of many studies. 

Further research is needed to investigate the interaction between intervention features and participant characteristics. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - V Ho, Betty P. V.: betty_ho@msn.com Ho, Betty P. V.: Macquarie University, Special Education Centre, Sydney, NSW, Australia, 2109, betty_ho@msn.com Ho, Betty P. V.: Macquarie University, Special Education Centre, Sydney, NSW, Australia Carter, Mark: Macquarie University, Special Education Centre, Sydney, NSW, Australia Stephenson, Jennifer: Macquarie University, Special Education Centre, Sydney, NSW, Australia
AN  - 2010-19595-002
AU  - Ho,
AU  - B.
AU  - P.
AU  - Carter,
AU  - M.
AU  - Stephenson,
AU  - J.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/1034912X.2010.501169
DP  - Ovid Technologies
KW  - anger management, cognitive-behavioral approach, children, special education needs, behavioral disorders, emotional disorders *Anger Control *Cognitive Behavior Therapy *Special Education Students *Special Needs Behavior Disorders Emotional Disturbances
LA  - English
M3  - Meta Analysis
PY  - 2010
SP  - 245-265
T2  - International Journal of Disability, Development and Education
TI  - Anger management using a cognitive-behavioural approach for children with special education needs: A literature review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc7&amp;AN=2010-19595-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F1034912X.2010.501169&amp;issn=1034-912X&amp;isbn=&amp;volume=57&amp;issue=3&amp;spage=245&amp;pages=245-265&amp;date=2010&amp;title=International+Journal+of+Disability%2C+Development+and+Education&amp;atitle=Anger+management+using+a+cognitive-behavioural+approach+for+children+with+special+education+needs%3A+A+literature+review+and+meta-analysis.&amp;aulast=Ho&amp;pid=%3Cauthor%3EHo%2C+Betty+P.+V%3C%2Fauthor%3E%3CAN%3E2010-19595-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/1034912X.2010.501169
VL  - 57
ER  -
TY  - JOUR
AB  - **BACKGROUND**
The purpose was to: 1) perform a systematic review of studies examining the relation between physical activity, fitness, and health in school-aged children and youth, and 2) make recommendations based on the findings. 

**METHODS** 
The systematic review was limited to 7 health indicators: high blood cholesterol, high blood pressure, the metabolic syndrome, obesity, low bone density, depression, and injuries. Literature searches were conducted using predefined keywords in 6 key databases. A total of 11,088 potential papers were identified. The abstracts and full-text articles of potentially relevant papers were screened to determine eligibility. Data was abstracted for 113 outcomes from the 86 eligible papers. The evidence was graded for each health outcome using established criteria based on the quantity and quality of studies and strength of effect. The volume, intensity, and type of physical activity were considered. 

**RESULTS**
Physical activity was associated with numerous health benefits. The dose-response relations observed in observational studies indicate that the more physical activity, the greater the health benefit. Results from experimental studies indicate that even modest amounts of physical activity can have health benefits in high-risk youngsters (e.g., obese). To achieve substantive health benefits, the physical activity should be of at least a moderate intensity. Vigorous intensity activities may provide even greater benefit. Aerobic-based activities had the greatest health benefit, other than for bone health, in which case high-impact weight bearing activities were required. 

**CONCLUSION:**
 The following recommendations were made: 1) Children and youth 5-17 years of age should accumulate an average of at least 60 minutes per day and up to several hours of at least moderate intensity physical activity. Some of the health benefits can be achieved through an average of 30 minutes per day. [Level 2, Grade A]. 2) More vigorous intensity activities should be incorporated or added when possible, including activities that strengthen muscle and bone [Level 3, Grade B]. 3) Aerobic activities should make up the majority of the physical activity. Muscle and bone strengthening activities should be incorporated on at least 3 days of the week [Level 2, Grade A].
AN  - 20459784
AU  - Janssen,
AU  - I.
AU  - Leblanc,
AU  - A.
AU  - G.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1186/1479-5868-7-40
L1  - internal-pdf://4017006052/Janssen-2010-Systematic review of the health b.pdf
PY  - 2010
SP  - 40
T2  - International Journal of Behavioral Nutrition &amp; Physical Activity
TI  - Systematic review of the health benefits of physical activity and fitness in school-aged children and youth
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=20459784
UR  - https://ijbnpa.biomedcentral.com/track/pdf/10.1186/1479-5868-7-40.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - This study investigated the efficacy of counseling and psychotherapy interventions for youth in schools. Data were examined for 107 studies that included 132 treatment interventions. Overall efficacy was d = 0.45 and was significantly different from zero. Interventions for adolescents outperformed those of children, treatment groups that were predominately female or male did better than mixed-gender groups, and licensed professional therapists outperformed paraprofessionals, who outperformed graduate students. Implications for supporting the mental health needs of youth in schools are discussed. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Baskin, Thomas W.: Baskin@UWM.edu Baskin, Thomas W.: University of Wisconsin-Milwaukee, School of Education, Department of Educational Psychology, Enderis Hall, 709, P.O. Box 413, Milwaukee, WI, US, 53201-0413, Baskin@UWM.edu Baskin, Thomas W.: University of Wisconsin-Milwaukee, Milwaukee, WI, US Slaten, Christopher D.: University of Wisconsin-Milwaukee, Milwaukee, WI, US Crosby, Nicole R.: University of Wisconsin-Milwaukee, Milwaukee, WI, US Pufahl, Tiffany: University of Wisconsin-Milwaukee, Milwaukee, WI, US Schneller, Cali L.: University of Wisconsin-Milwaukee, Milwaukee, WI, US Ladell, Monica: University of Wisconsin-Milwaukee, Milwaukee, WI, US
AN  - 2010-19031-001
AU  - Baskin,
AU  - T.
AU  - W.
AU  - Slaten,
AU  - C.
AU  - D.
AU  - Crosby,
AU  - N.
AU  - R.
AU  - Pufahl,
AU  - T.
AU  - Schneller,
AU  - C.
AU  - L.
AU  - Ladell,
AU  - M.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0011000010369497
DP  - Ovid Technologies
KW  - counseling, psychotherapy, treatment efficacy, schools, treatment outcomes *Counseling *Psychotherapy *School Based Intervention *Treatment Effectiveness Evaluation Treatment Outcomes Curriculum &amp; Programs &amp; Teaching Methods [3530] Human
LA  - English
M3  - Meta Analysis
PY  - 2010
SP  - 878-903
T2  - The Counseling Psychologist
TI  - Efficacy of counseling and psychotherapy in schools: A meta-analytic review of treatment outcome studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc7&amp;AN=2010-19031-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F0011000010369497&amp;issn=0011-0000&amp;isbn=&amp;volume=38&amp;issue=7&amp;spage=878&amp;pages=878-903&amp;date=2010&amp;title=The+Counseling+Psychologist&amp;atitle=Efficacy+of+counseling+and+psychotherapy+in+schools%3A+A+meta-analytic+review+of+treatment+outcome+studies.&amp;aulast=Baskin&amp;pid=%3Cauthor%3EBaskin%2C+Thomas+W%3C%2Fauthor%3E%3CAN%3E2010-19031-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://tcp.sagepub.com/content/38/7/878http://tcp.sagepub.com/content/38/7/878.full.pdf
VL  - 38
ER  -
TY  - JOUR
AB  - **AIM: **
To systematically review the literature on the effectiveness of early intervention programmes for children with physical disabilities. 

**METHODS:**
Twelve electronic databases were searched for articles published between 1990 and April 2008. The quality of articles was appraised using an adapted version of the Checklist for the Evaluation of Research Articles and the Physiotherapy Evidence Database (PEDro) scale. 

**RESULTS: **
Ten studies were included in the review. Cross-sectional and interrupted time-series studies were of moderate methodological quality, whereas the non-randomised control trial was of moderate-to-high methodological quality. Studies differed considerably with respect to participants, types of intervention and outcomes measured. 

**CONCLUSIONS: **
Positive outcomes for both children and families have resulted from early intervention. However, methodological limitations hamper a more rigorous analysis of findings across studies.
AD  - Ziviani,Jenny. Division of Occupational Therapy, The University of Queensland, Brisbane, Queensland, Australia. j.ziviani@uq.edu.au
AN  - 20854595
AU  - Ziviani,
AU  - J.
AU  - Feeney,
AU  - R.
AU  - Rodger,
AU  - S.
AU  - Watter,
AU  - P.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/j.1440-1630.2010.00850.x
DP  - Ovid Technologies
J2  - Aust Occup Ther J
KW  - Age Factors Child Child Development Child Welfare Child, Preschool Directive Counseling *Disabled Children/rh [Rehabilitation] Health Services Needs and Demand Humans Infant Infant, Newborn *Occupational Therapy/mt [Methods] Physicians *Program Evaluati
LA  - English
M3  - Review
N1  - Ziviani, Jenny Feeney, Rachel Rodger, Sylvia Watter, Pauline
PY  - 2010
SP  - 210-23
T2  - Australian Occupational Therapy Journal
TI  - Systematic review of early intervention programmes for children from birth to nine years who have a physical disability
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=20854595
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20854595&amp;id=doi:10.1111%2Fj.1440-1630.2010.00850.x&amp;issn=0045-0766&amp;isbn=&amp;volume=57&amp;issue=4&amp;spage=210&amp;pages=210-23&amp;date=2010&amp;title=Australian+Occupational+Therapy+Journal&amp;atitle=Systematic+review+of+early+intervention+programmes+for+children+from+birth+to+nine+years+who+have+a+physical+disability.&amp;aulast=Ziviani&amp;pid=%3Cauthor%3EZiviani+J%3C%2Fauthor%3E%3CAN%3E20854595%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1440-1630.2010.00850.x/asset/j.1440-1630.2010.00850.x.pdf?v=1&amp;t=ib3m54gl&amp;s=e815525744784f1ea4b59ed4386f97d61a302b37
UR  - http://onlinelibrary.wiley.com/doi/10.1111/j.1440-1630.2010.00850.x/abstract
VL  - 57
ER  -
TY  - JOUR
AB  - Over the past 20 years a variety of treatments have been developed to remediate deficits associated with autism. Since the early 1990s, Social Stories T have been suggested to positively affect the social development of children with autism spectrum disorder (ASD). Despite much research, there remains uncertainty regarding the effectiveness of this modality. 

We conducted a systematic review of the literature using pre-defined, rigorous methods. Studies were considered eligible if they were controlled trials evaluating Social Stories T among persons with ASD. 

Two reviewers independently screened articles for inclusion, applied eligibility criteria, extracted data, and assessed methodological quality. A qualitative analysis was conducted on six eligible controlled trials. Five of the six trials showed statistically significant benefits for a variety of outcomes related to social interaction. 

This review underscores the need for further rigorous research and highlights some outstanding questions regarding maintenance and generalization of the benefits of Social Stories (TM).
AD  - [Hartling, Lisa] Univ Alberta, Dept Pediat, Edmonton, AB T6G 2J3, Canada. Hartling, L (reprint author), Univ Alberta, Dept Pediat, Aberhart Ctr 1,Room 9424,11402 Univ Ave, Edmonton, AB T6G 2J3, Canada. hartling@ualberta.ca
AN  - WOS:000285243600008
AU  - Karkhaneh,
AU  - M.
AU  - Clark,
AU  - B.
AU  - Ospina,
AU  - M.
AU  - B.
AU  - Seida,
AU  - J.
AU  - C.
AU  - Smith,
AU  - V.
AU  - Hartling,
AU  - L.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1362361310373057
J2  - Autism
KW  - autism spectrum disorders systematic reviews Social Stories (TM) QUALITY TRIALS METAANALYSIS Psychology, Developmental
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 693RR Times Cited: 7 Cited Reference Count: 33 Karkhaneh, Mohammad Clark, Brenda Ospina, Maria B. Seida, Jennifer C. Smith, Veronica Hartling, Lisa 7 SAGE PUBLICATIONS LTD LONDON AUTISM
PY  - 2010
SP  - 641-662
T2  - Autism
TI  - Social Stories (TM) to improve social skills in children with autism spectrum disorder A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000285243600008http://aut.sagepub.com/content/14/6/641http://aut.sagepub.com/content/14/6/641.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/1362361310373057?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 14
ER  -
TY  - JOUR
AB  - **Objective:** 
The present study identifies and summarizes treatment effects for children and adolescent conduct problems based on accrued meta-analytic studies. 

**Method:** 
Systematic search and coding procedures were used to summarize studies from 1980 to 2007. 

**Results:** 
A total of 26 meta-analytic reviews composed of nearly 2,000 studies revealed substantial variation in effect sizes. The majority (45%) of effect sizes was small to medium in magnitude (d &lt; .36). In terms of the distribution of effect sizes (n = 125), the mean is d = 0.43 (SD = 0.32). 

**Conclusion:** 
Although there is considerable variation in effect sizes, the results seem to demonstrate evidence for equifinality. Furthermore, these effects are sturdy across a number of interrelated outcomes. Practitioners who work with children and adolescents should be aware of the range of evidence-based treatments available for conduct problems. Limitations of taking stock of treatment outcome literature via meta-analyses are highlighted. 
(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Vaughn, Michael G.: mvaughn9@slu.edu Vaughn, Michael G.: School of Social Work, Saint Louis University, 312 Tegeler Hall Frost Campus, St. Louis, MO, US, 63103-2097, mvaughn9@slu.edu Litschge, Christine M.: University of Pittsburgh, Pittsburgh, PA, US Vaughn, Michael G.: Saint Louis University, Saint Louis, MO, US McCrea, Cynthia: University of Pittsburgh, Pittsburgh, PA, US
AN  - 2009-23884-003
AU  - Litschge,
AU  - C.
AU  - M.
AU  - Vaughn,
AU  - M.
AU  - G.
AU  - McCrea,
AU  - C.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1049731508331247
DP  - Ovid Technologies
KW  - empirical status, treatments, conduct problems, treatment effects *Behavior Problems *Conduct Disorder *Treatment Health &amp; Mental Health Treatment &amp; Prevention [3300] Human
LA  - English
M3  - Meta Analysis
PY  - 2010
SP  - 21-35
T2  - Research on Social Work Practice
TI  - The empirical status of treatments for children and youth with conduct problems: An overview of meta-analytic studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc7&amp;AN=2009-23884-003 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1049731508331247&amp;issn=1049-7315&amp;isbn=&amp;volume=20&amp;issue=1&amp;spage=21&amp;pages=21-35&amp;date=2010&amp;title=Research+on+Social+Work+Practice&amp;atitle=The+empirical+status+of+treatments+for+children+and+youth+with+conduct+problems%3A+An+overview+of+meta-analytic+studies.&amp;aulast=Litschge&amp;pid=%3Cauthor%3ELitschge%2C+Christine+M%3C%2Fauthor%3E%3CAN%3E2009-23884-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rsw.sagepub.com/content/20/1/21http://rsw.sagepub.com/content/20/1/21.full.pdf
VL  - 20
ER  -
TY  - JOUR
AB  - A meta-analysis of single-subject research was conducted, examining the use of Social Stories and the role of a comprehensive set of moderator variables (intervention and participant characteristics) on intervention outcomes. 

While Social Stories had low to questionable overall effectiveness, they were more effective when addressing inappropriate behaviors than when teaching social skills. Social Stories also seemed to be associated with improved outcomes when used in general education settings and with target children as their own intervention agents. 

The role of other variables of interest, such as participants&#039; age, diagnosis, and skill development, the format of Social Stories, the length of the intervention, and the use of assessment (e.g., comprehension checks) also was explored.
AD  - Kokina,Anastasia. College of Education, Lehigh University, Bethlehem, PA 18015, USA. ank205@lehigh.edu
AN  - 20054628
AU  - Kokina,
AU  - A.
AU  - Kern,
AU  - L.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10803-009-0931-0
DP  - Ovid Technologies
J2  - J Autism Dev Disord
KW  - Adolescent Child Child Development Disorders, Pervasive/px [Psychology] *Child Development Disorders, Pervasive/th [Therapy] Child, Preschool Female Humans Infant Male *Social Behavior Students Treatment Outcome
LA  - English
M3  - Meta-Analysis
N1  - Kokina, Anastasia Kern, Lee
PY  - 2010
SP  - 812-26
T2  - Journal of Autism and Developmental Disorders
TI  - Social Story interventions for students with autism spectrum disorders: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=20054628 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20054628&amp;id=doi:10.1007%2Fs10803-009-0931-0&amp;issn=0162-3257&amp;isbn=&amp;volume=40&amp;issue=7&amp;spage=812&amp;pages=812-26&amp;date=2010&amp;title=Journal+of+Autism+%26+Developmental+Disorders&amp;atitle=Social+Story+interventions+for+students+with+autism+spectrum+disorders%3A+a+meta-analysis.&amp;aulast=Kokina&amp;pid=%3Cauthor%3EKokina+A%3C%2Fauthor%3E%3CAN%3E20054628%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10803-009-0931-0
UR  - https://link.springer.com/article/10.1007%2Fs10803-009-0931-0
VL  - 40
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Psychostimulants are first line of therapy for paediatric and adolescent AD/HD. The evidence suggests that up to 30% of those prescribed stimulant medications do not show clinically significant outcomes. In addition, many children and adolescents experience side-effects from these medications. As a result, parents are seeking alternate interventions for their children. Complementary and alternative medicine therapies for behavioural disorders such as AD/HD are increasing with as many as 68% of parents having sought help from alternative practitioners, including chiropractors. 

**OBJECTIVE: **
The review seeks to answer the question of whether chiropractic care can reduce symptoms of inattention, impulsivity and hyperactivity for paediatric and adolescent AD/HD. 

**METHODS: **
Electronic databases (Cochrane CENTRAL register of Controlled Trials, Cochrane Database of Systematic reviews, MEDLINE, PsycINFO, CINAHL, Scopus, ISI Web of Science, Index to Chiropractic Literature) were searched from inception until July 2009 for English language studies for chiropractic care and AD/HD. Inclusion and exclusion criteria were applied to select studies. All randomised controlled trials were evaluated using the Jadad score and a checklist developed from the CONSORT (Consolidated Standards of Reporting Trials) guidelines. 

**RESULTS: **
The search yielded 58 citations of which 22 were intervention studies. Of these, only three studies were identified for paediatric and adolescent AD/HD cohorts. The methodological quality was poor and none of the studies qualified using inclusion criteria. 

**CONCLUSIONS: **
To date there is insufficient evidence to evaluate the efficacy of chiropractic care for paediatric and adolescent AD/HD. The claim that chiropractic care improves paediatric and adolescent AD/HD, is only supported by low levels of scientific evidence. In the interest of paediatric and adolescent health, if chiropractic care for AD/HD is to continue, more rigorous scientific research needs to be undertaken to examine the efficacy and effectiveness of chiropractic treatment. Adequately-sized RCTs using clinically relevant outcomes and standardised measures to examine the effectiveness of chiropractic care verses no-treatment/placebo control or standard care (pharmacological and psychosocial care) are needed to determine whether chiropractic care is an effective alternative intervention for paediatric and adolescent AD/HD.
AD  - Karpouzis,Fay. Department of Chiropractic, Faculty of Science, Macquarie University, Sydney, NSW 2109, Australia. faykchiro@optusnet.com.au.
AN  - 20525195
AU  - Karpouzis,
AU  - F.
AU  - Bonello,
AU  - R.
AU  - Pollard,
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/1746-1340-18-13
DP  - Ovid Technologies
J2  - Chiropr Osteopat
LA  - English
N1  - Karpouzis, Fay Bonello, Rod Pollard, Henry
PY  - 2010
SP  - 13
T2  - Chiropractic &amp; Osteopathy [Electronic Resource]
TI  - Chiropractic care for paediatric and adolescent Attention-Deficit/Hyperactivity Disorder: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=20525195 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20525195&amp;id=doi:10.1186%2F1746-1340-18-13&amp;issn=1746-1340&amp;isbn=&amp;volume=18&amp;issue=&amp;spage=13&amp;pages=13&amp;date=2010&amp;title=Chiropractic+%26+Osteopathy+%5BElectronic+Resource%5D&amp;atitle=Chiropractic+care+for+paediatric+and+adolescent+Attention-Deficit%2FHyperactivity+Disorder%3A+A+systematic+review.&amp;aulast=Karpouzis&amp;pid=%3Cauthor%3EKarpouzis+F%3C%2Fauthor%3E%3CAN%3E20525195%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.chiromt.com/content/pdf/1746-1340-18-13.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - **Purpose: **
The Picture Exchange Communication System (PECS) is a popular communication-training program for young children with autism spectrum disorders (ASD). This meta-analysis reviews the current empirical evidence for PECS in affecting communication and speech outcomes for children with ASD.

**Method: **
A systematic review of the literature on PECS written between 1994 and June 2009 was conducted. Quality of scientific rigor was assessed and used as an inclusion criterion in computation of effect sizes. Effect sizes were aggregated separately for single-subject and group studies for communication and speech outcomes. 

**Results: **
Eight single-subject experiments (18 participants) and 3 group studies (95 PECS participants, 65 in other intervention/control) were included. Results indicated that PECS is a promising but not yet established evidence-based intervention for facilitating communication in children with ASD ages 1-11 years. Small to moderate gains in communication were demonstrated following training. Gains in speech were small to negative. 

**Conclusions: **
This meta-analysis synthesizes gains in communication and relative lack of gains made in speech across the PECS literature for children with ASD. Concerns about maintenance and generalization are identified. Emerging evidence of potential preintervention child characteristics is discussed. Phase IV was identified as a possibly influential program characteristic for speech outcomes.
AD  - [Flippin, Michelle] Univ N Carolina, Chapel Hill Div Speech &amp; Hearing Sci, Chapel Hill, NC 27599 USA. Flippin, M (reprint author), Univ N Carolina, Chapel Hill Div Speech &amp; Hearing Sci, Bondurant Hall,CB 7190, Chapel Hill, NC 27599 USA. mflippin@unc.edu
AN  - WOS:000279673700009
AU  - Flippin,
AU  - M.
AU  - Reszka,
AU  - S.
AU  - Watson,.
AU  - L.
AU  - R.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1044/1058-0360(2010/09-0022)
J2  - Am. J. Speech-Lang. Pathol.
KW  - autism Picture Exchange Communication System communication intervention speech SINGLE-SUBJECT RESEARCH SEVERE DEVELOPMENTAL-DISABILITIES SPECIAL-EDUCATION YOUNG-CHILDREN PHASE-III INTERVENTIONS PRESCHOOLERS ACQUISITION BEHAVIOR ADULTS Audiology &amp; Speech
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 622OS Times Cited: 26 Cited Reference Count: 72 Flippin, Michelle Reszka, Stephanie Watson, Linda R. 28 AMER SPEECH-LANGUAGE-HEARING ASSOC ROCKVILLE AM J SPEECH-LANG PAT
PY  - 2010
SP  - 178-195
T2  - American Journal of Speech-Language Pathology
TI  - Effectiveness of the Picture Exchange Communication System (PECS) on communication and speech for children with autism spectrum disorders: a meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000279673700009http://ajslp.pubs.asha.org/article.aspx?articleid=1757544
UR  - https://ajslp.pubs.asha.org/article.aspx?articleid=1757544
VL  - 19
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Uncertainty exists regarding the effects of iron supplementation on neurodevelopmental outcomes in the absence of anemia. 

**OBJECTIVE: **
Our objective was to evaluate the effects of iron supplementation in nonanemic pregnant women and in nonanemic healthy children aged &lt;3 y on the mental performance and psychomotor development of children. 

**DESIGN:**
In this systematic review, MEDLINE, EMBASE, and The Cochrane Library were searched through December 2009 for randomized controlled trials (RCTs). 

**RESULTS: **
None of 5 RCTs individually showed a beneficial effect of iron supplementation during early life on the Mental Developmental Index of the Bayley Scales of Infant Development at different ages throughout the first 18 mo. Meta-analysis of 3 RCTs (n = 561) showed that, compared with placebo, supplementation with iron had no significant effect on children&#039;s Mental Developmental Index at approximately 12 mo of age (weighted mean difference: 1.66; 95% CI: -0.14, 3.47). Three of 5 RCTs showed a beneficial effect of iron supplementation on the Psychomotor Development Index at some time points, whereas 2 did not. Meta-analysis of 3 RCTs (n = 561) showed significant improvement on the Psychomotor Development Index at approximately 12 mo of age in the iron-supplemented group compared with the control group (weighted mean difference: 4.21; 95% CI: 2.31, 6.12). Two RCTs showed no effect of iron supplementation on behavior. Neither of the 2 RCTs that addressed the influence of prenatal iron supplementation showed an effect of iron on either the intelligence quotient or behavioral status of the children. 

**CONCLUSION:** 
Limited available evidence suggests that iron supplementation in infants may positively influence children&#039;s psychomotor development, whereas it does not seem to alter their mental development or behavior.
AD  - Szajewska,Hania. Department of Paediatrics, The Medical University of Warsaw, Poland. hania@ipgate.pl &lt;hania@ipgate.pl&gt;
AN  - 20410098
AU  - Szajewska,
AU  - H.
AU  - Ruszczynski,
AU  - M.
AU  - Chmielewska,
AU  - A.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3945/ajcn.2010.29191
DP  - Ovid Technologies
J2  - Am J Clin Nutr
KW  - *Child Development/de [Drug Effects] Child Development/ph [Physiology] Child, Preschool *Cognition/de [Drug Effects] Cognition/ph [Physiology] Dietary Supplements Female Humans Infant *Iron/ad [Administration &amp; Dosage] Male Pregnancy *Psychomotor Perfor
L1  - internal-pdf://2828611448/Szajewska-2010-Effects of iron supplementation.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Szajewska, Hania Ruszczynski, Marek Chmielewska, Anna
PY  - 2010
SP  - 1684-90
T2  - American Journal of Clinical Nutrition
TI  - Effects of iron supplementation in nonanemic pregnant women, infants, and young children on the mental performance and psychomotor development of children: a systematic review of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=20410098
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20410098&amp;id=doi:10.3945%2Fajcn.2010.29191&amp;issn=0002-9165&amp;isbn=&amp;volume=91&amp;issue=6&amp;spage=1684&amp;pages=1684-90&amp;date=2010&amp;title=American+Journal+of+Clinical+Nutrition&amp;atitle=Effects+of+iron+supplementation+in+nonanemic+pregnant+women%2C+infants%2C+and+young+children+on+the+mental+performance+and+psychomotor+development+of+children%3A+a+systematic+review+of+randomized+controlled+trials.&amp;aulast=Szajewska&amp;pid=%3Cauthor%3ESzajewska+H%3C%2Fauthor%3E%3CAN%3E20410098%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ajcn.nutrition.org/content/91/6/1684.full.pdf
UR  - http://ajcn.nutrition.org/content/91/6/1684.full.pdf
VL  - 91
ER  -
TY  - JOUR
AB  - **Objective: **
To undertake a systematic review of the effects of exposure to mood stabilizer medication in pregnancy, evaluating teratogenicity and other outcomes for mother and child. This was one of three concurrent systematic reviews of psychotropic medication exposure in pregnancy. 

**Method: **
A systematic search was carried out of electronic databases, reference books and other sources for original research studies which examined the effects of commonly used mood stabilizers (sodium valproate, carbamazepine, lamotrigine and lithium carbonate) on pregnancy outcomes. These included malformations, pregnancy complications, neonatal complications and longer term developmental outcomes for children exposed. 

**Results: **
All mood stabilizers were found to be associated with a risk of malformation and perinatal complications. Studies which examined longer term neurodevelopmental outcomes found poorer outcomes for those children exposed to sodium valproate or polytherapy in pregnancy than for other individual AEDs. The data available for longer term child outcomes with lithium exposure is too limited to draw any conclusions. 

**Conclusions: **
This review found that exposure in pregnancy to all four commonly used mood stabilizers may be teratogenic, and is associated with increased rates of pregnancy and neonatal complications. There was also more limited information that sodium valproate may be associated with poorer longer term child developmental outcomes. These findings must be balanced with the risk of relapse and poor pregnancy and child outcomes with untreated maternal bipolar disorder. The information obtained from these reviews of psychotropic medications will assist clinicians in managing women with mental illness in pregnancy.
AD  - [Galbally, Megan; Perinatal Psychotropic Review Grp] Mercy Hosp Women, Heidelberg, Vic 3084, Australia. [Roberts, Matthew] Mercy Hlth, OConnell Family Ctr, Canterbury, Vic, Australia. [Buist, Anne] Univ Melbourne, Dept Psychiat, Melbourne, Vic 3010, Australia. Galbally, M (reprint author), Mercy Hosp Women, 163 Studley Rd, Heidelberg, Vic 3084, Australia. MGalbally@mercy.com.au
AN  - WOS:000283688800001
AU  - Galbally,
AU  - M.
AU  - Roberts,
AU  - M.
AU  - Buist,
AU  - A.
AU  - Perinatal
AU  - Psychotropic
AU  - Review
AU  - Group
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3109/00048674.2010.506637
J2  - Aust. N. Z. J. Psych.
KW  - mood stabilizers anti-epileptic drugs lithium carbonate pregnancy DRUGS IN-UTERO POSTNATALLY DEPRESSED MOTHERS ANTIEPILEPTIC DRUGS BIPOLAR DISORDER EPILEPTIC MOTHERS CHILDREN BORN COGNITIVE-DEVELOPMENT 5-YEAR-OLD CHILDREN MAJOR MALFORMATIONS GROWTH-RETA
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 673UK Times Cited: 27 Cited Reference Count: 90 Galbally, Megan Roberts, Matthew Buist, Anne 27 INFORMA HEALTHCARE NEW YORK AUST NZ J PSYCHIAT
PY  - 2010
SP  - 967-977
T2  - Australian and New Zealand Journal of Psychiatry
TI  - Mood stabilizers in pregnancy: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000283688800001http://anp.sagepub.com/content/44/11/967.longhttp://anp.sagepub.com/content/44/11/967.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.3109/00048674.2010.506637?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 44
ER  -
TY  - JOUR
AB  - **Background:** 
Clozapine is an atypical antipsychotic demonstrated to be superior in the treatment of refractory schizophrenia which causes fewer movement disorders. Clozapine, however, entails a significant risk of serious blood disorders such as agranulocytosis which could be potentially fatal. Currently there are a number of newer antipsychotics which have been developed with the purpose to find both a better tolerability profile and a superior effectiveness.

**Objectives:** 
To compare the clinical effects of clozapine with other atypical antipsychotics (such as amisulpride, aripiprazole, olanzapine, quetiapine, risperidone, sertindole, ziprasidone and zotepine) in the treatment of schizophrenia and schizophrenia-like psychoses.

**Search methods:** 
We searched the Cochrane Schizophrenia Groups Register (June 2007) and reference lists of all included randomised controlled trials. We also manually searched appropriate journals and conference proceedings relating to clozapine combination strategies and contacted relevant pharmaceutical companies.

**Selection criteria:** 
All relevant randomised, at least single-blind trials, comparing clozapine with other atypical antipsychotics, any dose and oral formulations, for people with schizophrenia or related disorders.

**Data collection and analysis:** 
We selected trials and extracted data independently. For dichotomous data we calculated relative risks (RR) and their 95% confidence intervals (CI) based on a random-effects model. We calculated numbers needed to treat/harm (NNT/NNH) where appropriate. For continuous data, we calculated mean differences (MD) again based on a random-effects model.

**Main results:** 
The review currently includes 27 blinded randomised controlled trials, which involved 3099 participants. Twelve randomised control trials compared clozapine with olanzapine, five with quetiapine, nine with risperidone, one with ziprasidone and two with zotepine. Attrition from these studies was high (overall 30.1%), leaving the interpretation of results problematic. Clozapine had a higher attrition rate due to adverse effects than olanzapine (9 RCTs, n=1674, RR 1.60 CI 1.07 to 2.40, NNT 25 CI 15 to 73) and risperidone (6 RCTs, n=627, RR 1.88 CI 1.11 to 3.21, NNT 16 CI 9 to 59). Fewer participants in the clozapine groups left the trials early due to inefficacy than risperidone (6 RCTs, n=627, RR 0.40 CI 0.23 to 0.70, NNT 11 CI 7 to 21), suggesting a certain higher efficacy of clozapine.Clozapine was more efficacious than zotepine in improving the participants general mental state (BPRS total score: 1 RCT, n=59, MD -6.00 CI -9.83 to -2.17), but not consistently more than olanzapine, quetiapine, risperidone and ziprasidone. There was no significant difference between clozapine and olanzapine or risperidone in terms of positive or negative symptoms of schizophrenia. According to two studies from China quetiapine was more efficacious for negative symptoms than clozapine (2 RCTs, n=142, MD 2.23 CI 0.99 to 3.48).Clozapine produced somewhat fewer extrapyramidal side-effects than risperidone (use of antiparkinson medication: 6 RCTs, n=304, RR 0.39 CI 0.22 to 0.68, NNT 7 CI 5 to 18) and zotepine (n=59, RR 0.05 CI 0.00 to 0.86, NNT 3 CI 2 to 5). More participants in the clozapine group showed decreased white blood cells than those taking olanzapine, more hypersalivation and sedation than those on olanzapine, risperidone and quetiapine and more seizures than people on olanzapine and risperidone. Also clozapine produced an important weight gain not seen with risperidone.Other differences in adverse effects were less documented and should be replicated, for example, clozapine did not alter prolactin levels whereas olanzapine, risperidone and zotepine did; compared with quetiapine, clozapine produced a higher incidence of electrocardiogram (ECG) alterations; and compared with quetiapine and risperidone clozapine produced a higher increase of triglyceride levels. Other findings that should be replicated were: clozapine improved social functioning less than risperidone and fewer participants in the clozapine r up had to be hospitalised to avoid suicide attempts compared to olanzapine. Other important outcomes such as service use, cognitive functioning, satisfaction with care or quality of life were rarely reported.

**Authors&#039; conclusions:** 
Clozapine may be a little more efficacious than zotepine and risperidone but further trials are required to confirm this finding. Clozapine differs more clearly in adverse effects from other second generation antipsychotics and the side-effect profile could be key in the selection of treatment depending on the clinical situation and a patient?s preferences. Data on other important outcomes such as cognitive functioning, quality of life, death or service use are currently largely missing, making further large and well-designed trials necessary. It is also important to take into account that the large number of people leaving the studies early limits the validity and interpretation of our findings.
AN  - CD006633
AU  - Asenjo,
AU  - C.
AU  - L.
AU  - Komossa,
AU  - K.
AU  - Rummel-Kluge,
AU  - C.
AU  - Hunger,
AU  - H.
AU  - Schmid,
AU  - F.
AU  - Schwarz,
AU  - S.
AU  - Leucht,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd006633
KW  - Antipsychotic Agents [therapeutic use]
KW  - Benzodiazepines [therapeutic use]
KW  - Clozapine [therapeutic use]
KW  - Dibenzothiazepines [therapeutic use]
KW  - Dibenzothiepins [therapeutic use]
KW  - Piperazines [therapeutic use]
KW  - Quetiapine Fumarate
KW  - Randomized Controlled Trials as Topic
KW  - Risperidone [therapeutic use]
KW  - Schizophrenia [drug therapy]
KW  - Thiazoles [therapeutic use]
KW  - Humans[checkword]
PY  - 2010
T2  - Cochrane Database of Systematic Reviews
TI  - Clozapine versus other atypical antipsychotics for schizophrenia
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006633.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006633.pub2/asset/CD006633.pdf?v=1&amp;t=iw7j2rc3&amp;s=1afc3bd02afb22c6dcdf47e1f2f2ae5ce3f315ca
ER  -
TY  - JOUR
AB  - **Background:** 
Neonatal abstinence syndrome (NAS) due to opiate withdrawal may result in disruption of the mother-infant relationship, sleep-wake abnormalities, feeding difficulties, weight loss and seizures.

**Objectives:** 
To assess the effectiveness and safety of using an opiate compared to a sedative or non-pharmacological treatment for treatment of NAS due to withdrawal from opiates.

**Search methods:** 
The review was updated in 2010 with additional searches CENTRAL, MEDLINE and EMBASE supplemented by searches of conference abstracts and citation lists of published articles.

**Selection criteria:** 
Randomized or quasi-randomized controlled trials of opiate treatment in infants with NAS born to mothers with opiate dependence.

**Data collection and analysis:** 
Each author assessed study quality and extracted data independently.

**Main results:** 
Nine studies enrolling 645 infants met inclusion criteria. There were substantial methodological concerns in all studies comparing an opiate with a sedative. Two small studies comparing different opiates were of good methodology.Opiate (morphine) versus supportive care (one study): A reduction in time to regain birth weight and duration of supportive care and a significant increase in hospital stay was noted.Opiate versus phenobarbitone (four studies): Meta-analysis found no significant difference in treatment failure. One study reported opiate treatment resulted in a significant reduction in treatment failure in infants of mothers using only opiates. One study reported a significant reduction in days treatment and admission to the nursery for infants receiving morphine. One study reported a reduction in seizures, of borderline statistical significance, with the use of opiate.Opiate versus diazepam (two studies): Meta-analysis found a significant reduction in treatment failure with the use of opiate.Different opiates (six studies): there is insufficient data to determine safety or efficacy of any specific opiate compared to another opiate.

**Authors&#039; conclusions:** 
Opiates compared to supportive care may reduce time to regain birth weight and duration of supportive care but increase duration of hospital stay. When compared to phenobarbitone, opiates may reduce the incidence of seizures but there is no evidence of effect on treatment failure. One study reported a reduction in duration of treatment and nursery admission for infants on morphine. Compared to diazepam, opiates reduce the incidence of treatment failure. A post-hoc analysis generates the hypothesis that initial opiate treatment may be restricted to infants of mothers who used opiates only. In view of the methodologic limitations of the included studies the conclusions of this review should be treated with caution.
AN  - CD002059
AU  - Osborn,
AU  - D.
AU  - A.
AU  - Jeffery,
AU  - H.
AU  - E.
AU  - Cole,
AU  - M.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd002059.pub2
KW  - Diazepam [therapeutic use]
KW  - Hypnotics and Sedatives [therapeutic use]
KW  - Morphine [therapeutic use]
KW  - Narcotics [therapeutic use]
KW  - Neonatal Abstinence Syndrome [drug therapy]
KW  - Opioid-Related Disorders [drug therapy]
KW  - Phenobarbital [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Humans[checkword]
KW  - Infant, Newborn[checkword]
KW  - Neonatal
PY  - 2010
T2  - Cochrane Database of Systematic Reviews
TI  - Opiate treatment for opiate withdrawal in newborn infants
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002059.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD002059.pub3/asset/CD002059.pdf?v=1&amp;t=iw7ugo4d&amp;s=dab694dad65eb48d7e3870b83ea222045e5bb8b4
ER  -
TY  - JOUR
AB  - **Objective: **
To review studies involving the treatment of anxiety in people with autism spectrum disorders (ASD) using Cognitive Behaviour Therapy (CBT) with the intent to inform practice and to identify areas for future research. 

**Methods: **
Systematic searches of electronic databases, reference lists and journals identified nine studies. Each identified study that met pre-determined inclusion criteria was analysed and summarized in terms of: (a) participants, (b) intervention procedures, (c) dependent variables, (d) results of intervention and (e) certainty of evidence. To assess the certainty of evidence, each study&#039;s design and related methodological details were critically appraised. 

**Results: **
Positive outcomes were ubiquitous, suggesting CBT is an effective treatment for anxiety in individuals with Asperger&#039;s. However, data involving other ASD diagnostic sub-types is limited. 

**Conclusions:** 
CBT has been modified for individuals with ASD by adding intervention components typically associated with applied behaviour analysis (e.g. systematic prompting and differential reinforcement). Future research involving a component analysis could potentially elucidate the mechanisms by which CBT reduces anxiety in individuals with ASD, ultimately leading to more efficient or effective interventions.
AD  - [Lang, Russell] Univ Calif Santa Barbara, Grad Sch Educ, Eli &amp; Edythe L Broad Asperger Res Ctr, Dept Special Educ,Koegel Autism Ctr, Santa Barbara, CA 93106 USA. [Lauderdale, Stacy] Univ Calif Riverside, Riverside, CA 92521 USA. Lang, R (reprint author), Univ Calif Santa Barbara, Grad Sch Educ, Eli &amp; Edythe L Broad Asperger Res Ctr, Dept Special Educ,Koegel Autism Ctr, Santa Barbara, CA 93106 USA. russlang@education.ucsb.edu
AN  - WOS:000284696400008
AU  - Lang,
AU  - R.
AU  - Regester,
AU  - A.
AU  - Lauderdale,
AU  - S.
AU  - Ashbaugh,
AU  - K.
AU  - Haring,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3109/17518420903236288
J2  - Dev. Neurorehabil.
KW  - Cognitive behaviour therapy Asperger&#039;s syndrome autism anxiety systematic review applied behaviour analysis HIGH-FUNCTIONING AUTISM RANDOMIZED CONTROLLED-TRIAL ASPERGER-SYNDROME CHILDREN SENSITIVITY INTERVENTIONS VALIDATION SYMPTOMS FUTURE ADULTS Clinic
L1  - internal-pdf://0561522879/Lang-2010-Treatment of anxiety in autism spect.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 686KY Times Cited: 38 Cited Reference Count: 68 Lang, Russell Regester, April Lauderdale, Stacy Ashbaugh, Kristen Haring, Anna van Lent, Laurence/G-5298-2010 van Lent, Laurence/0000-0002-9354-0932 38 INFORMA HEALTHCARE LONDON DEV NEUROREHABIL
PY  - 2010
SP  - 53-63
T2  - Developmental Neurorehabilitation
TI  - Treatment of anxiety in autism spectrum disorders using cognitive behaviour therapy: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000284696400008http://informahealthcare.com/doi/pdfplus/10.3109/17518420903236288
UR  - http://www.tandfonline.com/doi/pdf/10.3109/17518420903236288?needAccess=true
VL  - 13
ER  -
TY  - JOUR
AB  - **Objective: **
To assess the effectiveness of substance abuse interventions for their ability to reduce adolescent alcohol use. 

**Data Sources: **
MEDLINE; PsycINFO; ERIC; Wilson Social Science Abstracts; Criminal Justice Abstracts; Social Work Abstracts; Social Science Citation Index; Dissertations Abstracts International; National Criminal Justice Research Service; Social, Psychological, Criminological, Educational Trials Register; and the PsiTri databases from 1960 through 2008. 

**Study Selection: **
Of 64 titles and abstracts identified, 16 studies and 26 outcomes constituted the sample. The researchers calculated Hedges g effect sizes and used a random-effects model to calculate adjusted pooled effect sizes. Heterogeneity was explored using stratified analyses. 

**Main Exposure: **
Completion of a substance abuse intervention that aimed to reduce or eliminate alcohol consumption. 

**Main Outcome Measures: **
Abstinence, frequency of alcohol use, and quantity of alcohol use measured between 1 month and 1 year upon completion of treatment. 

**Results: **
Pooled effects of standardized mean differences indicate that interventions significantly reduce adolescent alcohol use (Hedges g=-0.61; 95% confidence interval [CI], -0.83 to -0.40). Stratified analyses revealed larger effects for individual treatment (Hedges g=-0.75; 95% CI, -1.05 to -0.40) compared with family- based treatments (Hedges g=-0.46; 95% CI, -0.66 to -0.26). 

**Conclusions: **
Treatments for adolescent substance abuse appear to be effective in reducing alcohol use. Individual-only interventions had larger effect sizes than family-based interventions and effect sizes decreased as length of follow-up increased. Furthermore, behavior-oriented treatments demonstrated promise in attaining long-term effects.
AD  - [Tripodi, Stephen J.] Florida State Univ, Coll Social Work, Tallahassee, FL 32306 USA. [Bender, Kimberly] Univ Denver, Denver, CO USA. [Litschge, Christy] Univ Pittsburgh, Pittsburgh, PA USA. [Vaughn, Michael G.] St Louis Univ, St Louis, MO 63103 USA. Tripodi, SJ (reprint author), Florida State Univ, Coll Social Work, 296 Champions Way,Univ Ctr Bldg C, Tallahassee, FL 32306 USA. stripodi@fsu.edu
AN  - WOS:000273262900012
AU  - Tripodi,
AU  - S.
AU  - J.
AU  - Bender,
AU  - K.
AU  - Litschge,
AU  - C.
AU  - Vaughn,
AU  - M.
AU  - G.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1001/archpediatrics.2009.235
J2  - Arch. Pediatr. Adolesc. Med.
KW  - MULTIDIMENSIONAL FAMILY-THERAPY ASSERTIVE CONTINUING CARE SUBSTANCE USE DISORDERS DRUG-ABUSE PSYCHIATRIC COMORBIDITY RESIDENTIAL-TREATMENT BEHAVIOR-THERAPY METAANALYSIS EFFICACY PSYCHOTHERAPIES Pediatrics
L1  - internal-pdf://0432144628/Tripodi-2010-Interventions for Reducing Adoles.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 539NY Times Cited: 39 Cited Reference Count: 50 Tripodi, Stephen J. Bender, Kimberly Litschge, Christy Vaughn, Michael G. Donald D. Hammill Foundation This study was supported by a grant from the Donald D. Hammill Foundation (Dr Vaughn). 41 AMER MEDICAL ASSOC CHICAGO ARCH PEDIAT ADOL MED
PY  - 2010
SP  - 85-91
T2  - Archives of Pediatrics and Adolescent Medicine
TI  - Interventions for Reducing Adolescent Alcohol Abuse A Meta-analytic Review
UR  - &lt;Go to ISI&gt;://WOS:000273262900012http://archpedi.jamanetwork.com/data/Journals/PEDS/5179/pra90002_85_91.pdf
UR  - https://jamanetwork.com/journals/jamapediatrics/articlepdf/382685/pra90002_85_91.pdf
VL  - 164
ER  -
TY  - JOUR
AB  - **Objective: **
Does juvenile system processing reduce subsequent delinquency? 

**Includsion Criteria: **
To be eligible, studies had to: (1) use random or quasi-random (e.g., alternation) assignment to allocate participants to conditions; (2) include only juvenile delinquents ages 17 and younger who have not yet been &ldquo;officially adjudicated&rdquo; for their current offense; (3) assign such participants to juvenile system processing -- or to an alternative non-system condition; (4) include at least one quantifiable outcome measure of criminal behavior; and (5) be reported through July 2008 (without regard to language). 

**Search Strategy: **
Fifteen experiments that met the eligibility criteria were identified from prior reviews conducted by the authors. To augment these 15 trials, we relied on electronic searches of 44 bibliographic databases, examined the citations in over 50 existing meta-analyses and reviews to identify additional randomized studies, and contacted researchers outside the .S. to identify non-US. studies. These additional search strategies yielded 40 studies that required inspection of full-text documents, resulting in an additional 14 experiments that met the eligibility criteria. Taken together with the existing 15 trials from our preceding reviews, these additional searches resulted in a final sample of 29 controlled trials. 

**Data Collection &amp; Analysis: **
A preliminary instrument was designed to extract data on substantive and methodological characteristics from each of the 29 trials. Standardized mean differences (Cohen&rsquo;s ) effect sizes were computed for the first, longest and strongest effects reported in each study for juvenile system processing, using Comprehensive Meta-Analysis (version 2)1. Given the heterogeneity of the sample, analyses of effect sizes were reported assuming random effects models. Main effects were analyzed for each type of crime measure reported: prevalence, incidence, severity and selfreport. Five moderating analyses were also conducted. 

**Main Results: **
The studies included 7,304 juveniles across 29 experiments reported over a 35-year period. Juvenile system processing, at least given the experimental evidence presented in this report, does not appear to have a crime control effect. In fact, almost all of the results are negative in direction, as measured by prevalence, incidence, severity, and self-report outcomes. The results are not uniform across every study; one important moderating variable is the type of control group. Studies that compared system processing to a diversion program reported much larger negative effect sizes than those that compared it to &ldquo;doing nothing. 

**Authors&#039; Conclusions: **
Based on the evidence presented in this report, juvenile system processing appears to not have a crime control effect, and across all measures appears to increase delinquency. This was true across measures of prevalence, incidence, severity, and self-report. Given the additional financial costs associated with system processing (especially when compared to doing nothing) and the lack of evidence for any public safety benefit, jurisdictions should review their policies regarding the handling of juveniles.
AU  - Petrosino,
AU  - A.,
AU  - Guckenburg,
AU  - S.,
AU  - Turpin-Petrosino,
AU  - C.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.4073/csr.2010.1
PY  - 2010
T2  - Campbell Systematic Reviews
TI  - Formal System Processing of Juveniles: Effects on Delinquency: A Systematic Review
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To compare antipsychotic and mood stabilizer (MS) efficacy and tolerability in youth and adults with bipolar mania. 

**METHODS: **
Medline/PubMed search for studies including: (i) youth (&lt; 18 years) or adults (&gt; or = 18 years); (ii) bipolar I disorder; (iii) double-blind, randomized, placebo-controlled trial (DB-RPCT); (iv) &lt; or = 12 weeks of treatment; and (v) calculable effect sizes (ES) and/or numbers needed to treat/harm (NNT/NNH) +/- 95% confidence intervals (CI). Non-overlapping 95% CIs determined significant group differences. 

**RESULTS:**
We identified nine DB-RPCTs in youth (n = 1,609), 5 evaluating second-generation antipsychotics (SGAs) (n = 1,140) and 4 evaluating MSs (n = 469). We also identified 23 DB-RPCTs in adults (n = 6,501), 14 including SGAs (n = 3,297), 5 using haloperidol as an active comparator (n = 580), and 11 including MSs (n = 2,581). Young Mania Rating Scale scores improved significantly more with SGAs than MSs in youth (ES = 0.65, CI: 0.53-0.78 versus 0.24, CI: 0.06-0.41) and adults (ES = 0.48, CI: 0.41-0.55 versus 0.24, CI: 0.17-0.31). After excluding topiramate studies, SGAs had larger ES than MSs only in youth (ES = 0.65, CI: 0.53-0.78 versus 0.20, CI: 0.02-0.39), but not adults (ES = 0.48, CI: 0.41-0.55 versus 0.46, CI: 0.37-0.55). However, in adults SGAs had significantly larger ES regarding Clinical Global Impressions scores than MSs, even without topiramate (ES = 0.75, CI: 0.68-0.82 versus 0.24, CI: 0.07-0.41). Rates of response, remission, and discontinuation due to any reason compared to placebo were similar between medication and age groups, except for more favorable NNTs for remission with SGAs than MSs in adults after excluding topiramate. SGAs caused more weight gain than MSs in youth (ES = 0.53, CI: 0.41-0.66 versus 0.10, CI: -0.12-0.33), but not in adults (ES = 0.13, CI: 0.05-0.22 versus 0.00, CI: -0.08-0.08). However, results were heterogeneous and not significant in either age group after excluding topiramate. Nevertheless, SGA-related weight gain was significantly greater in youth than adults. In youth, SGA-related somnolence was greater than with MSs (NNH = 4.7, CI: 3.9-6.0 versus 9.5, CI: 6.3-23.5), and more likely than in adults (NNH = 7.1, CI: 6.1-8.8). Conversely, youth experienced less akathisia with SGAs than adults (NNH = 20.4, CI: 14.1-36.5 versus 10.2, CI: 8.1-13.7), likely due to lower doses/slower titration. 

**CONCLUSIONS: **
In treating mania, potentially greater short-term efficacy compared to placebo with SGAs versus MS needs to be balanced against increased adverse events, especially in youth.
AD  - Correll,Christoph U. The Zucker Hillside Hospital, Psychiatry Research, North Shore-Long Island Jewish Health System, Glen Oaks, NY 11004, USA. ccorrell@lij.edu
AN  - 20402706
AU  - Correll,
AU  - C.
AU  - U.
AU  - Sheridan,
AU  - E.
AU  - M.
AU  - DelBello,
AU  - M.
AU  - P.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1399-5618.2010.00798.x
DP  - Ovid Technologies
J2  - Bipolar Disord
KW  - Adolescent Adult Age Factors Akathisia, Drug-Induced/et [Etiology] *Anti-Obesity Agents/ae [Adverse Effects] Anti-Obesity Agents/tu [Therapeutic Use] Antimanic Agents/ae [Adverse Effects] *Antimanic Agents/tu [Therapeutic Use] Antipsychotic Agents/ae [A
L1  - internal-pdf://2061560860/Correll-2010-Antipsychotic and mood stabilizer.pdf
LA  - English
M3  - Comparative Study Meta-Analysis
N1  - Correll, Christoph U Sheridan, Eva M DelBello, Melissa P UL1 TR000077 (United States NCATS NIH HHS)
PY  - 2010
SP  - 116-41
T2  - Bipolar Disorders
TI  - Antipsychotic and mood stabilizer efficacy and tolerability in pediatric and adult patients with bipolar I mania: a comparative analysis of acute, randomized, placebo-controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=20402706 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20402706&amp;id=doi:10.1111%2Fj.1399-5618.2010.00798.x&amp;issn=1398-5647&amp;isbn=&amp;volume=12&amp;issue=2&amp;spage=116&amp;pages=116-41&amp;date=2010&amp;title=Bipolar+Disorders&amp;atitle=Antipsychotic+and+mood+stabilizer+efficacy+and+tolerability+in+pediatric+and+adult+patients+with+bipolar+I+mania%3A+a+comparative+analysis+of+acute%2C+randomized%2C+placebo-controlled+trials.&amp;aulast=Correll&amp;pid=%3Cauthor%3ECorrell+CU%3C%2Fauthor%3E%3CAN%3E20402706%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1399-5618.2010.00798.x/asset/j.1399-5618.2010.00798.x.pdf?v=1&amp;t=ib7mjodm&amp;s=afa8c85b730c8df1e765adfc0c416161d0a647c8
UR  - http://onlinelibrary.wiley.com/store/10.1111/j.1399-5618.2010.00798.x/asset/j.1399-5618.2010.00798.x.pdf?v=1&amp;t=j8yga0gq&amp;s=ff3035eeb9a04fc2a7502a626031daf6563a390b
VL  - 12
ER  -
TY  - JOUR
AB  - The purpose of this meta-analytic review was to quantify the effects of psychological therapies for the management of chronic pain in youth. 
Specifically, in this review we updated previous systematic reviews of randomized controlled trials by including new trials, and by adding disability and emotional functioning to pain as treatment outcomes. 

Electronic searches of the Cochrane Register of Randomised Controlled Trials, MEDLINE, PsycLIT, EMBASE, and the Social Sciences Citation Index were conducted from inception through August 2008. 

Methodological quality of the studies was assessed, and data extracted on the three primary outcomes of interest. Twenty-five trials including 1247 young people met inclusion criteria and were included in the meta-analysis. 
Meta-analytic findings demonstrated a large positive effect of psychological intervention on pain reduction at immediate post-treatment and follow-up in youth with headache, abdominal pain, and fibromyalgia. 

Small and non-significant effects were found for improvements in disability and emotional functioning, although there were limited data on these outcomes available in the included studies. 

Omnibus cognitive-behavioral therapy, relaxation therapy, and biofeedback all produced significant and positive effects on pain reduction. Studies directly comparing the effects of self-administered versus therapist-administered interventions found similar effects on pain reduction. 

Psychological therapies result in improvement in pain relief across several different pain conditions in children. 

Future trials are needed that incorporate non-pain outcome domains, that focus significant therapeutic content on reductions in disability, and that include extended follow-up to better understand maintenance of treatment effects. 

(c) 2009 International Association for the Study of Pain. Published by Elsevier B. V. All rights reserved.
AD  - [Palermo, Tonya M.; Lewandowski, Amy S.] Oregon Hlth &amp; Sci Univ, Dept Anesthesiol &amp; Perioperat Med, Portland, OR 97239 USA. [Eccleston, Christopher] Univ Bath, Bath BA2 7AY, Avon, England. [Williams, Amanda C. de C.] UCL, Res Dept Clin Educ &amp; Hlth Psychol, London, England. [Morley, Stephen] Univ Leeds, Leeds Inst, Hlth Serv, Leeds, W Yorkshire, England. Palermo, TM (reprint author), Oregon Hlth &amp; Sci Univ, Dept Anesthesiol &amp; Perioperat Med, Mail Code UHN 2,3181 SW Sam Jackson Pk Rd, Portland, OR 97239 USA. palermot@ohsu.edu
AN  - WOS:000274550400009
AU  - Palermo,
AU  - T.
AU  - M.
AU  - Eccleston,
AU  - C.
AU  - Lewandowski,
AU  - A.
AU  - S.
AU  - de
AU  - Williams,
AU  - A.
AU  - C.
AU  - Morley,
AU  - S.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.pain.2009.10.004
J2  - Pain
KW  - Psychological therapies Randomized controlled trials Chronic pain Pain Children Meta-analysis Systematic review EMPIRICALLY SUPPORTED TREATMENTS RECURRENT ABDOMINAL-PAIN PEDIATRIC PSYCHOLOGY CHRONIC HEADACHES INTERVENTION RELAXATION MIGRAINE QUALITY REC
L1  - internal-pdf://3167644158/Palermo-2010-Randomized controlled trials of p.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 555XP Times Cited: 89 Cited Reference Count: 43 Palermo, Tonya M. Eccleston, Christopher Lewandowski, Amy S. Williams, Amanda C. de C. Morley, Stephen International Association for the Study of Pain Collaborative Research; NIH [K24HD060068] This work was partially supported by an International Association for the Study of Pain Collaborative Research Grant awarded to T.P. and C.E. and by NIH K24HD060068 (T.P.). We would like to thank Hannah Somhegyi and Simona Patange for their assistance with data extraction and coding. In addition, we thank the following authors, Drs. Carrie Hicks, Paul Robins, Lisa Scharff, and Carl von Baeyer who provided additional data from their studies for the meta-analysis. 93 ELSEVIER SCIENCE BV AMSTERDAM PAIN
PY  - 2010
SP  - 387-397
T2  - Pain
TI  - Randomized controlled trials of psychological therapies for management of chronic pain in children and adolescents: An updated meta-analytic review
UR  - &lt;Go to ISI&gt;://WOS:000274550400009http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823996/pdf/nihms152400.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823996/pdf/nihms152400.pdf
VL  - 148
ER  -
TY  - JOUR
AB  - **Objective: **
To identify and describe current internet-based prevention and treatment programs for anxiety and depression in children and adolescents. 

**Data sources: **
Systematic search of the Cochrane Library, PsycINFO and PubMed databases conducted in June 2009. 

**Study selection: **
Studies of internet-based programs that addressed anxiety or depression in children and adolescents. No restrictions were placed on study quality. 

**Data synthesis: **
Eight studies of four intervention programs were identified. Programs were delivered via schools, in primary care, through mental health clinics or open access websites. Two were treatment programs, three offered universal prevention, two were indicated prevention programs, and one was a selective prevention program. Study quality was mixed, with three randomised controlled trials in which participants were randomly allocated to the intervention or control condition, one randomised uncontrolled trial, two controlled trials in which participants were not randomly assigned to conditions, and two uncontrolled pre-post evaluations. Two studies targeted anxiety in children, while the remainder addressed depression, or anxiety and depression, in adolescents. All the interventions were based on cognitive behaviour therapy, and six of the eight studies reported post-intervention reductions in symptoms of anxiety and/or depression or improvements in diagnostic ratings. Three of these studies also reported improvements at follow-up.

**Conclusion: **
Our findings provide early support for the effectiveness of internet-based programs for child and adolescent anxiety and depression. More extensive and rigorous research is needed to further establish the conditions through which effectiveness is enhanced, as well as to develop additional programs to address gaps in the field. 

MJA 2010; 192: S12-S14
AD  - [Calear, Alison L.; Christensen, Helen] Australian Natl Univ, Mental Hlth Res Ctr, Canberra, ACT, Australia. Calear, AL (reprint author), Australian Natl Univ, Mental Hlth Res Ctr, Canberra, ACT, Australia. Alison.Calear@anu.edu.au
AN  - WOS:000278950600003
AU  - Calear,
AU  - A.
AU  - L.
AU  - Christensen,
AU  - H.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /pubmed/20528700
J2  - Med. J. Aust.
KW  - CONTROLLED-TRIAL DISORDERS CHILDHOOD SYMPTOMS EFFICACY THERAPY PROJECT Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 613BI Times Cited: 36 Cited Reference Count: 22 Calear, Alison L. Christensen, Helen Calear, Alison/D-4191-2009 Calear, Alison/0000-0002-7028-725X 36 AUSTRALASIAN MED PUBL CO LTD PYRMONT MED J AUSTRALIA S
PY  - 2010
SP  - S12-S14
T2  - Medical Journal of Australia
TI  - Review of internet-based prevention and treatment programs for anxiety and depression in children and adolescents
UR  - &lt;Go to ISI&gt;://WOS:000278950600003https://www.mja.com.au/system/files/issues/192_11_070610/cal10829_fm.pdf
VL  - 192
ER  -
TY  - JOUR
AB  - We present the results of a meta-analytic review of early developmental prevention programs (children aged 0-5: structured preschool programs, center-based developmental day care, home visitation, family support services and parental education) delivered to at-risk populations on non-health outcomes during adolescence (educational success, cognitive development, social-emotional development, deviance, social participation, involvement in criminal justice, and family well-being). This review improves on previous meta-analyses because it includes a more comprehensive set of adolescent outcomes, it focuses on measures that are psychometrically valid, and it includes a more detailed analysis of program moderator effects. Seventeen studies, based on eleven interventions (all US-based) met the ten criteria for inclusion into the analysis. The mean effect size across all programs and outcomes was 0.313, equivalent to a 62% higher mean score for an intervention group than for a control group. The largest effect was for educational success during adolescence (effect size 0.53) followed by social deviance (0.48), social participation (0.37), cognitive development (0.34), involvement in criminal justice (0.24), family well-being (0.18), and social-emotional development (0.16). Programs that lasted longer than three years were associated with larger sample means than programs that were longer than one year but shorter than three years. More intense programs (those with more than 500 sessions per participant) also had larger means than less intense programs. There was a marginally significant trend for programs with a follow-through component into the early primary school years (e.g. preschool to Grade 3) to have more positive effects than programs without a follow-through. We conclude that the impact of well-conducted early development programs on quality of life in adolescence can be substantial for social policy purposes. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Manning, Matthew: m.manning@griffith.edu.au; Homel, Ross: r.homel@griffith.edu.au; Smith, Christine: christine.smith@griffith.edu.au Manning, Matthew: Key Centre for Ethics, Law, Justice and Governance, Griffith University, Mt Gravatt Campus, Brisbane, QLD, Australia, 4111, m.manning@griffith.edu.au Manning, Matthew: Key Centre for Ethics, Law, Justice and Governance, Griffith University, Brisbane, QLD, Australia Homel, Ross: Institute for Social and Behavioural Research, Griffith University, Brisbane, QLD, Australia Smith, Christine: School of Accounting, Finance and Economics, Griffith University, Brisbane, QLD, Australia
AN  - 2010-02598-005
AU  - Manning,
AU  - M.
AU  - Homel,
AU  - R.
AU  - Smith,
AU  - C.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2009.11.003
DP  - Ovid Technologies
KW  - early developmental prevention programs, at-risk populations, non-health outcomes, adolescence *Adolescent Development *At Risk Populations *Health *Well Being Early Childhood Development Health &amp; Mental Health Treatment &amp; Prevention [3300] Human
LA  - English
M3  - Meta Analysis
PY  - 2010
SP  - 506-519
T2  - Children and Youth Services Review
TI  - A meta-analysis of the effects of early developmental prevention programs in at-risk populations on non-health outcomes in adolescence
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc7&amp;AN=2010-02598-005 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.childyouth.2009.11.003&amp;issn=0190-7409&amp;isbn=&amp;volume=32&amp;issue=4&amp;spage=506&amp;pages=506-519&amp;date=2010&amp;title=Children+and+Youth+Services+Review&amp;atitle=A+meta-analysis+of+the+effects+of+early+developmental+prevention+programs+in+at-risk+populations+on+non-health+outcomes+in+adolescence.&amp;aulast=Manning&amp;pid=%3Cauthor%3EManning%2C+Matthew%3C%2Fauthor%3E%3CAN%3E2010-02598-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0190740909003132/1-s2.0-S0190740909003132-main.pdf?_tid=1cbc2210-18cd-11e5-a013-00000aab0f6b&amp;acdnat=1434970673_30c3ccf3313571acb4f976c590e8c8ab
VL  - 32
ER  -
TY  - JOUR
AB  - **OBJECTIVE:** 
To systematically evaluate the effects of n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) supplementation of pregnant and/or lactating women on the neurodevelopment and visual function of their children.

**METHODS:** 
Systematic review. Randomized controlled trials (RCTs) comparing n-3 LCPUFA maternal supplementation were identified through electronic databases (MEDLINE, EMBASE, the Cochrane Library) and the references of reviewed articles.

**RESULTS:** 
Overall, 13 publications, some with important methodological limitations, were included. With regard to supplementation during pregnancy, among 3 RCTs that evaluated this intervention, 1 RCT (n = 72) showed significantly better eye and hand coordination assessed with the Griffiths Mental Development Scales at 30 months of age. Another RCT (n = 29) demonstrated an effect of n-3 LCPUFA supplementation on the cloth step of intentional solutions of the 2-step problem-solving test. No other effects were demonstrated. There was no consistent effect of n-3 LCPUFA supplementation during pregnancy on the children&#039;s visual acuity. With regard to supplementation during lactation, among 3 RCTs that assessed this intervention, 1 RCT (n =133) showed significant improvement on the Bayley Psychomotor Development Index in 30-month-old children; however, there was no influence of such supplementation on the results of different tests performed in the same group of children or in others. There was no consistent effect of n-3 LCPUFA supplementation during lactation on the children&#039;s visual function. Supplementation during pregnancy and lactation (3 RCTs) did not affect child neurodevelopment assessed up to 7 years of age.

**CONCLUSION:** 
Evidence from RCTs does not demonstrate a clear and consistent benefit of n-3 LCPUFA supplementation during pregnancy and/or lactation on child neurodevelopment and visual acuity. These results should be interpreted with caution due to methodological limitations of the included studies.
AD  - Dziechciarz, Piotr. Department of Paediatrics, The Medical University of Warsaw, Dzialdowska 1, 01-184 Warsaw, Poland.
AN  - 21504971
AU  - Dziechciarz,
AU  - P.
AU  - Horvath,
AU  - A.
AU  - Szajewska,
AU  - H.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/07315724.2010.10719881
DP  - Ovid Technologies
J2  - J Am Coll Nutr
KW  - Breast Feeding
KW  - Child, Preschool
KW  - *Cognition/de [Drug Effects]
KW  - *Dietary Fats/pd [Pharmacology]
KW  - *Dietary Supplements
KW  - *Fatty Acids, Omega-3/pd [Pharmacology]
KW  - Female
KW  - Humans
KW  - *Nervous System/de [Drug Effects]
KW  - Nervous System/gd [Growth &amp; Development]
KW  - Pregnancy
KW  - Randomized Controlled Trials as Topic
KW  - *Vision, Ocular/de [Drug Effects]
KW  - *Visual Acuity/de [Drug Effects]
KW  - 0 (Dietary Fats)
KW  - 0 (Fatty Acids, Omega-3)
L1  - internal-pdf://0750805971/Dziechciarz-2010.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
Review
Systematic Review
N1  - Dziechciarz, PiotrHorvath, AndreaSzajewska, Hania
PY  - 2010
SP  - 443-54
T2  - Journal of the American College of Nutrition
TI  - Effects of n-3 long-chain polyunsaturated fatty acid supplementation during pregnancy and/or lactation on neurodevelopment and visual function in children: a systematic review of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=21504971
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21504971&amp;id=doi:10.1080%2F07315724.2010.10719881&amp;issn=0731-5724&amp;isbn=&amp;volume=29&amp;issue=5&amp;spage=443&amp;pages=443-54&amp;date=2010&amp;title=Journal+of+the+American+College+of+Nutrition&amp;atitle=Effects+of+n-3+long-chain+polyunsaturated+fatty+acid+supplementation+during+pregnancy+and%2For+lactation+on+neurodevelopment+and+visual+function+in+children%3A+a+systematic+review+of+randomized+controlled+trials.&amp;aulast=Dziechciarz&amp;pid=%3Cauthor%3EDziechciarz+P%3C%2Fauthor%3E%3CAN%3E21504971%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.tandfonline.com/doi/full/10.1080/07315724.2010.10719881
UR  - https://www.tandfonline.com/doi/pdf/10.1080/07315724.2010.10719881?needAccess=true
VL  - 29
ER  -
TY  - JOUR
AB  - **Background: **
Posttraumatic stress disorder (PTSD), one of the possible consequences of sexual abuse of children and adolescents, may be found in about 40% to 50% of the cases. 

**Objective: **
Conduct a systematic review of studies investigating the use of cognitive behavioral therapy (CBT) for the treatment of sexually abused children and adolescents with PTSD. 

**Methods: **
A search for randomized clinical trials that evaluated PTSD in children and adolescents from 1980 to February 1, 2006 was conducted in the following databases: MedLine, EMBASE, LILACS, PsycLIT, PsycINFO, Cochrane Depression, Anxiety and Neurosis Group Database of Trials, Cochrane Controlled Trials Register, Science Citation Index (SciSearch), and PILOTS. References in all clinical trials selected were hand-searched.

**Results: **
Of the 43 studies initially selected, only three met inclusion criteria. The following comparisons were found in the studies: CBT to treat child and family member versus no treatment (waiting list); CBT to treat only child, only parents, or both versus community care; and trauma-focused CBT versus child-centered therapy (CCT). Results for CBT treatment of PTSD were better than no treatment (waiting list) (p &lt; 0.05), community care (p &lt; 0.01) and CCT (p &lt; 0.01). The comparison of child-only CBT and family CBT (parents or caretakers and children) did not reveal any significant differences in efficacy, and both showed significant improvement of symptoms. A meta-analysis was conducted to compare the efficacy of CBT (child-only and family) versus no treatment (waiting list and community care) in the remission of patients who completed treatment. Remission rates in treatment and control groups were 60% and 20%, and this difference in favor of CBT was statistically significant (RR = 0.51; 95%CI 0.29-0.88; p = 0.02). No controlled studies were found that compared CBT and pharmacotherapy. 

**Discussion: **
Treatment with CBT reduces PTSD symptoms in sexually abused children and adolescents, with no differences between therapy with only the victim or with the victim and a family member. No studies compared CBT and pharmacotherapy or the efficacy of combined treatments.
AD  - (Passarela, Mendes, De Jesus Mari) Departamento de Psiquiatria, Universidade Federal de Sao Paulo (Unifesp), Rua Botucatu, 740, 04023-900 - Sao Paulo, SP, Brazil J. De Jesus Mari, Departamento de Psiquiatria, Universidade Federal de Sao Paulo (Unifesp), Rua Botucatu, 740, 04023-900 - Sao Paulo, SP, Brazil. E-mail: jamari@attglobal.net
AN  - 2010322204
AU  - Passarela,
AU  - C.
AU  - D.
AU  - M.
AU  - Mendes,
AU  - D.
AU  - D.
AU  - De
AU  - Jesus
AU  - Mari,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1590/S0101-60832010000200006
DP  - Ovid Technologies
KW  - Children ptsd Sexual abuse Systematic review Treatment adolescent child child sexual abuse/th [Therapy] clinical trial Cochrane Library cognitive therapy community care controlled clinical trial Embase family therapy human Medline meta analysis posttrau
LA  - Portuguese, English
M3  - Review
PY  - 2010
SP  - 63-73
T2  - Revista de Psiquiatria Clinica
TI  - A systematic review to study the efficacy of cognitive behavioral therapy for sexually abused children and adolescents with posttraumatic stress disorder. [Portuguese, English]
UR  - http://www.scielo.br/pdf/rpc/v37n2/en_a06v37n2.pdf http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed9&amp;AN=2010322204 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1590%2FS0101-60832010000200006&amp;issn=0101-6083&amp;isbn=&amp;volume=37&amp;issue=2&amp;spage=63&amp;pages=63-73&amp;date=2010&amp;title=Revista+de+Psiquiatria+Clinica&amp;atitle=Revisao+sistematica+para+estudar+a+eficacia+de+terapia+cognitivo-comportamental+para+criancas+e+adolescentes+abusadas+sexualmente+com+transtorno+de+estresse+pos-traumatico&amp;aulast=Passarela&amp;pid=%3Cauthor%3EPassarela+C.D.M.%3C%2Fauthor%3E%3CAN%3E2010322204%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3E
VL  - 37
ER  -
TY  - JOUR
AB  - Stimulants used to treat attention-deficit/hyperactivity disorder (ADHD) have been well researched, but comparisons among stimulants are hindered by the absence of direct comparative trials. The goal of this work was to compare the efficacy of methylphenidate and amfetamine formulations through a meta-analysis of double-blind placebo-controlled trials. We analyzed recent published literature on the stimulant therapy of ADHD to describe the variability of drug-placebo effect sizes. 

A literature search was conducted to identify double-blind, placebo-controlled studies of ADHD in children and adolescents published after 1979. Meta-analysis regression assessed the influence of medication type and study design features on medication effects. Twenty-three trials met criteria and were included in this meta-analysis. These trials studied 11 drugs using 19 different outcome measures of hyperactive, inattentive, or impulsive behavior. We found significant differences between amfetamine and methylphenidate products, even after correcting for study design features that might have confounded the results. 

Our analyses indicate that effect sizes for amfetamine products are significantly, albeit moderately, greater than those for methylphenidate. We found that most measures of effect from all studies were statistically significant. 

Our findings suggest that amfetamine products may be moderately more efficacious than methylphenidate products, even after controlling for potentially confounding study design features. 

This difference in effect size may be due to differences between amfetamine and methylphenidate in the molecular mechanisms involved in facilitating the dopaminergic neurotransmission.
AD  - Faraone,Stephen V. Departments of Psychiatry and Neuroscience &amp; Physiology, SUNY Upstate Medical University, Syracuse, NY, USA. faraones@upstate.edu
AN  - 19763664
AU  - Faraone,
AU  - S.
AU  - V.
AU  - Buitelaar,
AU  - J.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-009-0054-3
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
KW  - Adolescent Adult Attention Deficit Disorder with Hyperactivity/di [Diagnosis] *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] Attention Deficit Disorder with Hyperactivity/px [Psychology] *Central Nervous System Stimulants/tu [Therapeut
LA  - English
M3  - Comparative Study Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Faraone, Stephen V Buitelaar, Jan
PY  - 2010
SP  - 353-64
T2  - European Child &amp; Adolescent Psychiatry
TI  - Comparing the efficacy of stimulants for ADHD in children and adolescents using meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19763664 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19763664&amp;id=doi:10.1007%2Fs00787-009-0054-3&amp;issn=1018-8827&amp;isbn=&amp;volume=19&amp;issue=4&amp;spage=353&amp;pages=353-64&amp;date=2010&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=Comparing+the+efficacy+of+stimulants+for+ADHD+in+children+and+adolescents+using+meta-analysis.&amp;aulast=Faraone&amp;pid=%3Cauthor%3EFaraone+SV%3C%2Fauthor%3E%3CAN%3E19763664%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://download.springer.com/static/pdf/771/art%253A10.1007%252Fs00787-009-0054-3.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-009-0054-3&amp;token2=exp=1434977876~acl=%2Fstatic%2Fpdf%2F771%2Fart%25253A10.1007%25252Fs00787-009-0054-3.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-009-0054-3*~hmac=4abc2fa0877c47cde35ef9ad8b9c883fabeeedb2f3b2d15f9eeca422e33e3a48
VL  - 19
ER  -
TY  - JOUR
AB  - The main objective of this review was to provide a quantitative and methodologically sound evaluation of existing treatments for bereavement and grief reactions in children and adolescents. 

Two meta-analyses were conducted: 1 on controlled studies and 1 on uncontrolled studies. The 2 meta-analyses were based on a total of 27 treatment studies published before June 2006. Hedges&#039;s g and Cohen&#039;s d were used as measures of effect size and a random-effects model was applied. 

Results yielded small to moderate effect sizes. Interventions for symptomatic or impaired participants tended to show larger effect sizes than interventions for bereaved children and adolescents without symptoms. 

Promising treatment models were music therapy and trauma/grief-focused school based brief psychotherapy.
AD  - Rosner,Rita. Department of Psychology, Ludwig Maximilians University of Munich, Munich, Germany. rosner@psy.uni-muenchen.de Kruse,Joachim. Department of Psychology, Ludwig Maximilians University of Munich, Munich, Germany. Hagl,Maria. Department of Psychology, Ludwig Maximilians University of Munich, Munich, Germany.
AN  - 24479177
AU  - Rosner,
AU  - R.
AU  - Kruse,
AU  - J.
AU  - Hagl,
AU  - M.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/07481180903492422
DP  - Ovid Technologies
J2  - Death Stud
KW  - Adolescent *Adolescent Behavior/px [Psychology] Child *Child Behavior/px [Psychology] Child Psychiatry/og [Organization &amp; Administration] *Cognitive Therapy/mt [Methods] *Crisis Intervention/mt [Methods] Female *Grief Humans Life Change Events Male Qual
LA  - English
N1  - Rosner, Rita Kruse, Joachim Hagl, Maria
PY  - 2010
SP  - 99-136
T2  - Death Studies
TI  - A meta-analysis of interventions for bereaved children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=24479177 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:24479177&amp;id=doi:&amp;issn=0748-1187&amp;isbn=&amp;volume=34&amp;issue=2&amp;spage=99&amp;pages=99-136&amp;date=2010&amp;title=Death+Studies&amp;atitle=A+meta-analysis+of+interventions+for+bereaved+children+and+adolescents.&amp;aulast=Rosner&amp;pid=%3Cauthor%3ERosner+R%3C%2Fauthor%3E%3CAN%3E24479177%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/07481180903492422
VL  - 34
ER  -
TY  - JOUR
AB  - **Background:**
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common developmental disorders experienced in childhood and can persist into adulthood. The disorder has early onset and is characterized by a combination of overactive, poorly modulated behavior with marked inattention. In the long term it can impair academic performance, vocational success and social-emotional development. Meditation is increasingly used for psychological conditions and could be used as a tool for attentional training in the ADHD population.

**Objectives:** 
To assess the effectiveness of meditation therapies as a treatment for ADHD.Search methods: Our extensive search included: CENTRAL, MEDLINE, EMBASE, CINAHL, ERIC, PsycINFO, C2-SPECTR, dissertation abstracts, LILACS, Virtual Health Library (VHL) in BIREME, Complementary and Alternative Medicine specific databases, HSTAT, Informit, JST, Thai Psychiatric databases and ISI Proceedings, plus grey literature and trial registries from inception to January 2010.

**Selection criteria:** 
Randomized controlled trials that investigated the efficacy of meditation therapy in children or adults diagnosed with ADHD.

**Data collection and analysis:** 
Two authors extracted data independently using a pre-designed data extraction form. We contacted study authors for additional information required. We analyzed data using mean difference (MD) to calculate the treatment effect. The results are presented in tables, figures and narrative form.

**Main results:**
Four studies, including 83 participants, are included in this review. Two studies used mantra meditation while the other two used yoga compared with drugs, relaxation training, non-specific exercises and standard treatment control. Design limitations caused high risk of bias across the studies. Only one out of four studies provided data appropriate for analysis. For this study there was no statistically significant difference between the meditation therapy group and the drug therapy group on the teacher rating ADHD scale (MD -2.72, 95% CI -8.49 to 3.05, 15 patients). Likewise, there was no statistically significant difference between the meditation therapy group and the standard therapy group on the teacher rating ADHD scale (MD -0.52, 95% CI -5.88 to 4.84, 17 patients). There was also no statistically significant difference between the meditation therapy group and the standard therapy group in the distraction test (MD -8.34, 95% CI -107.05 to 90.37, 17 patients).

**Authors&#039; conclusions:** 
As a result of the limited number of included studies, the small sample sizes and the high risk of bias, we are unable to draw any conclusions regarding the effectiveness of meditation therapy for ADHD. The adverse effects of meditation have not been reported. More trials are needed.
AN  - CD006507
AU  - Krisanaprakornkit,
AU  - T.
AU  - Ngamjarus,
AU  - C.
AU  - Witoonchart,
AU  - C.
AU  - Piyavhatkul,
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd006507.pub2
KW  - Yoga
KW  - Attention Deficit Disorder with Hyperactivity [drug therapy] [therapy]
KW  - Meditation [methods]
KW  - Relaxation Therapy [methods]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Behav
PY  - 2010
T2  - Cochrane Database of Systematic Reviews
TI  - Meditation therapies for attention-deficit/hyperactivity disorder (ADHD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006507.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006507.pub2/asset/CD006507.pdf?v=1&amp;t=iw7k3s4s&amp;s=ba27b4250ec8e306322797e6c697409f1ef94696
ER  -
TY  - JOUR
AB  - This paper presents a best evidence synthesis of interventions to increase social behavior for individuals with autism. Sixty-six studies published in peer-reviewed journals between 2001 and July 2008 with 513 participants were included. 

The results are presented by the age of the individual receiving intervention and by delivery agent of intervention. The findings suggest there is much empirical evidence supporting many different treatments for the social deficits of individuals with autism. 

Using the criteria of evidence-based practice proposed by Reichow et al. (Journal of Autism and Developmental Disorders, 38: 1311-1318, 2008), social skills groups and video modeling have accumulated the evidence necessary for the classifications of established EBP and promising EBP, respectively. 

Recommendations for practice and areas of future research are provided.
AD  - [Reichow, Brian; Volkmar, Fred R.] Yale Univ, Sch Med, Ctr Child Study, New Haven, CT 06510 USA. Reichow, B (reprint author), Yale Univ, Sch Med, Ctr Child Study, 40 Temple St,Suite 7-1, New Haven, CT 06510 USA. brian.reichow@yale.edu
AN  - WOS:000274374200002
AU  - Reichow,
AU  - B.
AU  - Volkmar.
AU  - F.
AU  - R.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10803-009-0842-0
J2  - J. Autism Dev. Disord.
KW  - Autism Social skills Evidence-based practice HIGH-FUNCTIONING AUTISM TYPICALLY DEVELOPING PEERS TEACH PERSPECTIVE-TAKING SPECTRUM DISORDERS YOUNG-CHILDREN JOINT ATTENTION ASPERGER-SYNDROME COMMUNICATION INTERVENTION MODELING INTERVENTIONS CONVERSATION S
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 553NN Times Cited: 80 Cited Reference Count: 119 Reichow, Brian Volkmar, Fred R. 82 SPRINGER/PLENUM PUBLISHERS NEW YORK J AUTISM DEV DISORD
PY  - 2010
SP  - 149-166
T2  - Journal of Autism and Developmental Disorders
TI  - Social Skills Interventions for Individuals with Autism: Evaluation for Evidence-Based Practices within a Best Evidence Synthesis Framework
UR  - &lt;Go to ISI&gt;://WOS:000274374200002
UR  - https://link.springer.com/article/10.1007%2Fs10803-009-0842-0
VL  - 40
ER  -
TY  - JOUR
AB  - **Aim**
To determine if there is a relationship between maternal methadone dose in pregnancy and the diagnosis or medical treatment of neonatal abstinence syndrome (NAS). 

**Methods** 
PubMed, EMBASE, the Cochrane Library and PsychINFO were searched for studies reporting on methadone use in pregnancy and NAS (1966-2009). The relative risk (RR) of NAS was compared for methadone doses above versus below a range of cut-off points. Summary RRs and 95% confidence intervals (CI) were estimated using random effects meta-analysis. Sensitivity analyses explored the impact of limiting meta-analyses to prospective studies or studies using an objective scoring system to diagnose NAS. 

**Results** A total of 67 studies met inclusion criteria for the systematic review; 29 were included in the meta-analysis. Any differences in the incidence of NAS in infants of women on higher compared with lower doses were statistically non-significant in analyses restricted to prospective studies or to those using an objective scoring system to diagnose NAS. 

**Conclusions**
Severity of the neonatal abstinence syndrome does not appear to differ according to whether mothers are on high- or low-dose methadone maintenance therapy.
AD  - [Cleary, Brian J.; Donnelly, Jean; Murphy, Deirdre J.] Coombe Women &amp; Infants Univ Hosp, Dublin 8, Ireland. [Cleary, Brian J.; Strawbridge, Judith; Gallagher, Paul J.] Royal Coll Surgeons Ireland, Sch Pharm, Dublin 2, Ireland. [Cleary, Brian J.; Murphy, Deirdre J.] Trinity Coll Dublin, Dept Obstet &amp; Gynaecol, Dublin, Ireland. [Fahey, Tom] Royal Coll Surgeons Ireland, Div Populat Hlth Sci, HRB Ctr Primary Care Res, Dublin 2, Ireland. [Clarke, Mike] UK Cochrane Ctr, Oxford, England. [Clarke, Mike] Trinity Coll Dublin, Sch Nursing &amp; Midwifery, Dublin, Ireland. Cleary, BJ (reprint author), Coombe Women &amp; Infants Univ Hosp, Dublin 8, Ireland. bcleary@coombe.ie
AN  - WOS:000283946600010
AU  - Cleary,
AU  - B.
AU  - J.
AU  - Donnelly,
AU  - J.
AU  - Strawbridge,
AU  - J.
AU  - Gallagher,
AU  - P.
AU  - J.
AU  - Fahey,
AU  - T.
AU  - Clarke,
AU  - M.
AU  - Murphy,
AU  - D.
AU  - J.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/j.1360-0443.2010.03120.x
J2  - Addiction
KW  - Meta-analysis methadone neonate neonatal abstinence syndrome pregnancy systematic review withdrawal MATERNAL OPIATE USE NARCOTIC WITHDRAWAL DEPENDENT WOMEN NEWBORN-INFANTS PREGNANT-WOMEN MAINTENANCE TREATMENT COMPREHENSIVE CARE TREATMENT PROGRAM OUTCOME
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 676VK Times Cited: 39 Cited Reference Count: 105 Cleary, Brian J. Donnelly, Jean Strawbridge, Judith Gallagher, Paul J. Fahey, Tom Clarke, Mike Murphy, Deirdre J. Fahey, Tom/C-9367-2012 Fahey, Tom/0000-0002-5896-5783 charity Friends of the Coombe; School of Pharmacy, Royal College of Surgeons in Ireland B.C. was funded by the charity Friends of the Coombe and the School of Pharmacy, Royal College of Surgeons in Ireland. None of the researchers have any connections with the tobacco, alcohol, pharmaceutical or gaming industries or any body substantially funded by one of these organizations. No contractual constraints on publishing were imposed by the funding bodies. 39 WILEY-BLACKWELL PUBLISHING, INC MALDEN ADDICTION
PY  - 2010
SP  - 2071-2084
T2  - Addiction
TI  - Methadone dose and neonatal abstinence syndrome-systematic review and meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000283946600010http://onlinelibrary.wiley.com/store/10.1111/j.1360-0443.2010.03120.x/asset/j.1360-0443.2010.03120.x.pdf?v=1&amp;t=ib3kz912&amp;s=b8895b81663376797bc749fc573edc29d83bed01
VL  - 105
ER  -
TY  - JOUR
AB  - Touch establishes powerful physical and emotional connections between infants and their caregivers, and plays an essential role in development. The objective of this systematic review was to identify published research to ascertain whether tactile stimulation is an effective intervention to support mental and physical health in physically healthy infants. 

Twenty-two studies of healthy infants with a median age of six months or less met our inclusion criteria. The limited evidence suggests that infant massage may have beneficial effects on sleeping and crying patterns, infants&#039; physiological responses to stress (including reductions in serum levels of norepinephrine and epinephrine, and urinary cortisol levels), establishing circadian rhythms through an increase in the secretion of melatonin, improving interaction between mother-infant dyads in which the mother is postnatally depressed, and promoting growth and reducing illness for limited populations (i.e. infants in an orphanage where routine tactile stimulation is low). 

The only other evidence of a significant impact of massage on growth in infants living in families was obtained from a group of studies regarded to be at high risk of bias which we have reported separately. There is no evidence of a beneficial effect on infant temperament, attachment or cognitive development. 

There is, therefore, some evidence of benefits on mother-infant interaction, sleeping and crying, and on hormones influencing stress levels. In the absence of evidence of harm, these findings support the use of infant massage in the community, particularly in contexts where infant stimulation is poor. 

Further research is needed, however, before it will be possible to recommend universal provision.
AD  - [Underdown, Angela; Barlow, Jane; Stewart-Brown, Sarah] Univ Warwick, Sch Med, Coventry CV4 7AL, W Midlands, England. Underdown, A (reprint author), Univ Warwick, Sch Med, Coventry CV4 7AL, W Midlands, England. A.V.Underdown@warwick.ac.uk
AN  - WOS:000277585400003
AU  - Underdown,
AU  - A.
AU  - Barlow,
AU  - J.
AU  - Stewart-Brown,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/02646830903247209
J2  - J. Reprod. Infant Psychol.
KW  - tactile stimulation infants systematic review MASSAGE THERAPY POSTNATAL DEPRESSION GROWTH INTERVENTION MOTHERS TOUCH CHINA Psychology, Multidisciplinary
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 595BJ Times Cited: 7 Cited Reference Count: 64 Underdown, Angela Barlow, Jane Stewart-Brown, Sarah 7 ROUTLEDGE JOURNALS, TAYLOR &amp; FRANCIS LTD ABINGDON J REPROD INFANT PSYC
PY  - 2010
SP  - 11-29
T2  - Journal of Reproductive and Infant Psychology
TI  - Tactile stimulation in physically healthy infants: results of a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000277585400003http://www.tandfonline.com/doi/pdf/10.1080/02646830903247209
VL  - 28
ER  -
TY  - JOUR
AB  - STUDY OBJECTIVE: We evaluate the effectiveness of interventions for pediatric patients with suicide-related emergency department (ED) visits.

METHODS: We searched of MEDLINE, EMBASE, the Cochrane Library, other electronic databases, references, and key journals/conference proceedings. We included experimental or quasiexperimental studies that evaluated psychosocial interventions for pediatric suicide-related ED visits. Inclusion screening, study selection, and methodological quality were assessed by 2 independent reviewers. One reviewer extracted the data and a second checked for completeness and accuracy. Consensus was reached by conference; disagreements were adjudicated by a third reviewer. We calculated odds ratios, relative risks (RRs), or mean differences for each study&#039;s primary outcome, with 95% confidence intervals (CIs). Meta-analysis was deferred because of clinical heterogeneity in intervention, patient population, and outcome.

RESULTS: We included 7 randomized controlled trials and 3 quasiexperimental studies, grouping and reviewing them according to intervention delivery: ED-based delivery (n=1), postdischarge delivery (n=6), and ED transition interventions (n=3). An ED-based discharge planning intervention increased the number of attended post-ED treatment sessions (mean difference=2.6 sessions; 95% CI 0.05 to 5.15 sessions). Of the 6 studies of postdischarge delivery interventions, 1 found increased adherence with service referral in patients who received community nurse home visits compared with simple placement referral at discharge (RR=1.28; 95% CI 1.06 to 1.56). The 3 ED transition intervention studies reported (1) reduced risk of subsequent suicide after brief ED intervention and postdischarge contact (RR=0.10; 95% CI 0.03 to 0.41); (2) reduced suicide-related hospitalizations when ED visits were followed up with interim, psychiatric care (RR=0.41; 95% CI 0.28 to 0.60); and (3) increased likelihood of treatment completion when psychiatric evaluation in the ED was followed by attendance of outpatient sessions with a parent (odds ratio=2.78; 95% CI 1.20 to 6.67).

CONCLUSION: Transition interventions appear most promising for reducing suicide-related outcomes and improving post-ED treatment adherence. Use of similar interventions and outcome measures in future studies would enhance the ability to derive strong recommendations from the clinical evidence in this area.
AD  - Newton, Amanda S. Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada. mandi.newton@ualberta.ca
AN  - 20381916
AU  - Newton,
AU  - A.
AU  - S.
AU  - Hamm,
AU  - M.
AU  - P.
AU  - Bethell,
AU  - J.
AU  - Rhodes,
AU  - A.
AU  - E.
AU  - Bryan,
AU  - C.
AU  - J.
AU  - Tjosvold,
AU  - L.
AU  - Ali,
AU  - S.
AU  - Logue,
AU  - E.
AU  - Manion,
AU  - I.
AU  - G.
DA  - Dec
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1016/j.annemergmed.2010.02.026
DP  - Ovid Technologies
J2  - Ann Emerg Med
KW  - Adolescent
KW  - Child
KW  - Confidence Intervals
KW  - Emergency Service, Hospital/og [Organization &amp; Administration]
KW  - Emergency Service, Hospital/st [Standards]
KW  - Emergency Service, Hospital/sn [Statistics &amp; Numerical Data]
KW  - *Emergency Service, Hospital
KW  - Humans
KW  - Mental Health Services/st [Standards]
KW  - Mental Health Services/sn [Statistics &amp; Numerical Data]
KW  - *Mental Health Services
KW  - Odds Ratio
KW  - Patient Discharge/st [Standards]
KW  - Patient Discharge/sn [Statistics &amp; Numerical Data]
KW  - Referral and Consultation/st [Standards]
KW  - Referral and Consultation/sn [Statistics &amp; Numerical Data]
KW  - Risk
KW  - Suicide, Attempted/pc [Prevention &amp; Control]
KW  - Suicide, Attempted/sn [Statistics &amp; Numerical Data]
KW  - *Suicide, Attempted
L1  - internal-pdf://0519946013/Newton-2010-Pediatric suicide-related presenta.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
Review
Systematic Review
N1  - Newton, Amanda SHamm, Michele PBethell, JenniferRhodes, Anne EBryan, Craig JTjosvold, LisaAli, SaminaLogue, ErinManion, Ian G
PY  - 2010
SP  - 649-59
T2  - Annals of Emergency Medicine
TI  - Pediatric suicide-related presentations: a systematic review of mental health care in the emergency department
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=20381916
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20381916&amp;id=doi:10.1016%2Fj.annemergmed.2010.02.026&amp;issn=0196-0644&amp;isbn=&amp;volume=56&amp;issue=6&amp;spage=649&amp;pages=649-59&amp;date=2010&amp;title=Annals+of+Emergency+Medicine&amp;atitle=Pediatric+suicide-related+presentations%3A+a+systematic+review+of+mental+health+care+in+the+emergency+department.&amp;aulast=Newton&amp;pid=%3Cauthor%3ENewton+AS%3C%2Fauthor%3E%3CAN%3E20381916%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012108/pdf/nihms1629.pdf
VL  - 56
ER  -
TY  - JOUR
AB  - A systematic review was conducted to identify and describe school-based prevention and early intervention programs for depression and to evaluate their effectiveness in reducing depressive symptoms. 

Forty-two randomised controlled trials, relating to 28 individual school-based programs, were identified through the Cochrane Library, PsychInfo and PubMed databases. 
A large proportion of the programs identified were based on cognitive behavioural therapy (CBT), and delivered by a mental health professional or graduate student over 8-12 sessions. 

Indicated programs, which targeted students exhibiting elevated levels of depression, were found to be the most effective, with effect sizes for all programs ranging from 0.21 to 1.40. 

Teacher program leaders and the employment of attention control conditions were associated with fewer significant effects. Further school-based research is required that involves the use of attention controls, long-term follow-ups and which focuses on the training and evaluation of sustainable program leaders, such as teachers. 

(C) 2009 The Association for Professionals in Services for Adolescents. 
Published by Elsevier Ltd. All rights reserved.
AD  - [Calear, Alison L.; Christensen, Helen] Australian Natl Univ, Mental Hlth Res Ctr, Canberra, ACT 0200, Australia. Calear, AL (reprint author), Australian Natl Univ, Mental Hlth Res Ctr, Bldg 63,Eggleston Rd, Canberra, ACT 0200, Australia. Alison.Calear@anu.edu.au
AN  - WOS:000278647100010
AU  - Calear,
AU  - A.
AU  - L.
AU  - Christensen,
AU  - H.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.adolescence.2009.07.004
J2  - J. Adolesc.
KW  - Review Depression School-based Child Adolescent PENN RESILIENCY PROGRAM LONG-TERM OUTCOMES CONTROLLED-TRIAL FOLLOW-UP ANXIETY SYMPTOMS RANDOMIZED-TRIAL ADOLESCENTS CHILDREN UNIVERSAL PILOT Psychology, Developmental
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 609HP Times Cited: 45 Cited Reference Count: 69 Calear, Alison L. Christensen, Helen Calear, Alison/D-4191-2009; Christensen, Helen/F-5053-2012 Calear, Alison/0000-0002-7028-725X; 45 ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD LONDON J ADOLESCENCE
PY  - 2010
SP  - 429-438
T2  - Journal of Adolescence
TI  - Systematic review of school-based prevention and early intervention programs for depression
UR  - &lt;Go to ISI&gt;://WOS:000278647100010http://ac.els-cdn.com/S0140197109001006/1-s2.0-S0140197109001006-main.pdf?_tid=6301eb30-165a-11e5-bf69-00000aab0f6b&amp;acdnat=1434701496_a48138e3a521f5e42a930490e0cd341b
VL  - 33
ER  -
TY  - JOUR
AB  - Research suggests that involvement in relational aggression is associated with serious adjustment problems, including concurrent and future social maladjustment (e.g., problematic friendships; rejection), internalizing problems (e.g., depressive symptoms), and school avoidance. Despite the burgeoning literature focusing on the harmful and damaging nature of relationally aggressive behavior, this research has only recently begun to be used to inform school-based prevention and intervention programming. This article reviews the developmental research related to relational aggression and presents a systematic examination of nine published school-based prevention and intervention programs to prevent relational aggression. Programs reviewed target preschool through eighth-grade students. Strengths and limitations of each program are discussed. Recommendations are offered for future research to develop and validate school-based programming for relational aggression, and implications for school psychologists are discussed. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Leff, Stephen S.: leff@email.chop.edu Leff, Stephen S.: Children&#039;s Hospital of Philadelphia, Department of Pediatric Psychology, Rm. 1480, CHOP North, 3405 Civic Center Blvd., Philadelphia, PA, US, 19104, leff@email.chop.edu Leff, Stephen S.: Children s Hospital of Philadelphia, Philadelphia, PA, US Waasdorp, Tracy Evian: Children&#039;s Hospital of Philadelphia, Philadelphia, PA, US Crick, Nicki R.: Center on Relational Aggression, University of Minnesota, MN, US
AN  - 2011-00267-002
AU  - Leff,
AU  - S.
AU  - S.
AU  - Waasdorp,
AU  - T.
AU  - E.
AU  - Crick,
AU  - N.
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Har ikke DOI: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111222/
DP  - Ovid Technologies
KW  - program strengths, social maladjustment, internalizing problems, school avoidance, aggressive behavior, school based intervention, preschool students *Aggressive Behavior *Educational Programs *Preschool Students *School Based Intervention *Social Adjus
LA  - English
M3  - Literature Review
PY  - 2010
SP  - 508-535
T2  - School Psychology Review
TI  - A review of existing relational aggression programs: Strengths, limitations, and future directions
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc7&amp;AN=2011-00267-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=0279-6015&amp;isbn=&amp;volume=39&amp;issue=4&amp;spage=508&amp;pages=508-535&amp;date=2010&amp;title=School+Psychology+Review&amp;atitle=A+review+of+existing+relational+aggression+programs%3A+Strengths%2C+limitations%2C+and+future+directions.&amp;aulast=Leff&amp;pid=%3Cauthor%3ELeff%2C+Stephen+S%3C%2Fauthor%3E%3CAN%3E2011-00267-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 39
ER  -
TY  - JOUR
AB  - Forty-eight child psychotherapy outcome studies offering direct comparisons of an individual child treatment group to a combined parent-child/family therapy treatment group were included in this meta-analytic review. 

Results indicate that combined treatments produced a moderate effect beyond the outcomes achieved by individual child treatments, with an average weighted effect size that is within the medium range (d = 0.27). 

Moderator analysis indicated that, compared to non-cognitive-behavioral individual child treatments, cognitive-behavioral individual child treatments were closer in effectiveness to the overall more effective treatments that included parent participation. 

Results suggest that including parents in the psychotherapeutic treatment of children adds benefits beyond the outcomes achieved by individual child therapies. 

More research is needed on factors affecting parents&#039; engagement and consistent participation in child psychotherapy treatment and on clinician&#039;s utilization of parents as therapy coparticipants.
AD  - Dowell,Kathy A. Department of Psychology, University of Minnesota Duluth, 326 Bohannon Hall, 1207 Ordean Court, Duluth, MN 55812, USA. kdowell@d.umn.edu
AN  - 20390807
AU  - Dowell,
AU  - K.
AU  - A.
AU  - Ogles,
AU  - B.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://doi.org/10.1080/15374410903532585
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
KW  - Adolescent Adult Child *Child Behavior Disorders/th [Therapy] Humans *Parent-Child Relations *Psychotherapy/mt [Methods] Randomized Controlled Trials as Topic Treatment Outcome
LA  - English
M3  - Meta-Analysis
N1  - Dowell, Kathy A Ogles, Benjamin M
PY  - 2010
SP  - 151-62
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - The effects of parent participation on child psychotherapy outcome: a meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=20390807
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20390807&amp;id=doi:10.1080%2F15374410903532585&amp;issn=1537-4416&amp;isbn=&amp;volume=39&amp;issue=2&amp;spage=151&amp;pages=151-62&amp;date=2010&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=The+effects+of+parent+participation+on+child+psychotherapy+outcome%3A+a+meta-analytic+review.&amp;aulast=Dowell&amp;pid=%3Cauthor%3EDowell+KA%3C%2Fauthor%3E%3CAN%3E20390807%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/15374410903532585
VL  - 39
ER  -
TY  - JOUR
AB  - The effectiveness of behavioural intervention programs for children with Autistic Spectrum Disorders was addressed by a meta-analysis, which reviewed 14 studies. 

The findings suggest that the behavioural programs are effective in improving several developmental aspects in the children, in terms of their treatment gains, and also relative to eclectic-control programs in the same studies. 

Factors that were found to be correlated with the effectiveness of the behavioural programs were the intensity and the duration of the programs, the parental training, as well as the age and the adaptive behaviour abilities of the children at intake. 

The review showed that the high intensity of the programs is correlated with better gains in some developmental domains. 

Moreover, the high adaptive behaviour abilities and the young age of the children are also related with better progress the children have in some specific domains. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Makrygianni, Maria K.: mmakrigianni@yahoo.gr; Reed, Phil: p.reed@swansea.ac.uk Makrygianni, Maria K.: Department of Psychology, Swansea University, Singleton Park, Swansea, United Kingdom, SA2 8PP, mmakrigianni@yahoo.gr Makrygianni, Maria K.: Department of Psychology, Swansea University, Singleton Park, Swansea, United Kingdom Reed, Phil: Swansea University, Swansea, United Kingdom
AN  - 2010-11895-005
AU  - Raffin,
AU  - M.
AU  - Makrygianni,
AU  - K.
AU  - Reed,
AU  - P.
DA  - Oct-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.rasd.2010.01.014
DP  - Ovid Technologies
KW  - behavioral early intervention programs, autistic spectrum disorders, effectiveness *Behavior Therapy *Early Intervention *Pervasive Developmental Disorders *Treatment Effectiveness Evaluation Behavior Therapy &amp; Behavior Modification [3312] Human Childho
LA  - English
M3  - Meta Analysis
PY  - 2010
SP  - 577-593
T2  - Research in Autism Spectrum Disorders
TI  - A meta-analytic review of the effectiveness of behavioural early intervention programs for children with autistic spectrum disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc7&amp;AN=2010-11895-005 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.rasd.2010.01.014&amp;issn=1750-9467&amp;isbn=&amp;volume=4&amp;issue=4&amp;spage=577&amp;pages=577-593&amp;date=2010&amp;title=Research+in+Autism+Spectrum+Disorders&amp;atitle=A+meta-analytic+review+of+the+effectiveness+of+behavioural+early+intervention+programs+for+children+with+autistic+spectrum+disorders.&amp;aulast=Makrygianni&amp;pid=%3Cauthor%3EMakrygianni%2C+Maria+K%3C%2Fauthor%3E%3CAN%3E2010-11895-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1750946710000152/1-s2.0-S1750946710000152-main.pdf?_tid=95b0d390-167b-11e5-82eb-00000aacb35d&amp;acdnat=1434715755_a5886a38eb9ef21c6c05f47ad0fa9837
VL  - 4
ER  -
TY  - JOUR
AB  - **CONTEXT: **
To date, there has not been clear evidence regarding interventions that are effective in addressing the specific needs of homeless youth. A systematic and comprehensive international review on effective interventions for homeless youth is presented. This study seeks to provide an accurate and complete picture of effective interventions for homeless youth by collecting, summarizing, categorizing, and evaluating quantitative studies (i.e., those that have assessed treatment outcomes). 

**EVIDENCE ACQUISTION: **
The following databases were searched in 2008: PsycINFO, ERIC, MEDLINE, and Cochrane were searched from 1985 through 2008 using specific key words: interventions and programs, with homeless youth (s), homeless adolescents, street youth (s), runaways and throwaways. In addition, references of key articles were searched by hand. Eleven studies met pre-established inclusion criteria. To determine study quality, a set of operational parameters was formulated to rate each study as either good, fair, or poor. 

**EVIDENCE SYNTHESIS: **
There is no compelling evidence that specific interventions are effective for homeless youth, owing to moderate study quality and the small number of intervention studies. Conclusions that can be drawn from the studies are limited by the heterogeneity of interventions, participants, methods, and outcome measures. Many interventions focused on reduction of substance abuse, whereas other important outcomes, such as quality of life, have received little attention. No study received a quality rating of good, and four studies were rated as fair. Most convincing, but still marginal, were results of interventions based on cognitive-behavioral approaches, which revealed some positive results on psychological measures. 

**CONCLUSIONS: **
More methodologically sound research is needed to determine what specific interventions are beneficial for subgroups of homeless youth. Implications for future research are discussed.

Copyright 2010 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.
AD  - Altena,Astrid M. Radboud University Nijmegen Medical Centre, The Netherlands. a.altena@elg.umcn.nl
AN  - 20494240
AU  - Altena,
AU  - A.
AU  - M.
AU  - Brilleslijper-Kater,
AU  - S.
AU  - N.
AU  - Wolf,
AU  - J.
AU  - L.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.amepre.2010.02.017
DP  - Ovid Technologies
J2  - Am J Prev Med
KW  - Adolescent Child Cognitive Therapy/mt [Methods] Female *Health Services *Homeless Persons Humans Intervention Studies Male *Quality of Life Substance-Related Disorders/rh [Rehabilitation] Young Adult
LA  - English
M3  - Review
N1  - Altena, Astrid M Brilleslijper-Kater, Sonja N Wolf, Judith L M
PY  - 2010
SP  - 637-45
T2  - American Journal of Preventive Medicine
TI  - Effective interventions for homeless youth: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=20494240
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20494240&amp;id=doi:10.1016%2Fj.amepre.2010.02.017&amp;issn=0749-3797&amp;isbn=&amp;volume=38&amp;issue=6&amp;spage=637&amp;pages=637-45&amp;date=2010&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=Effective+interventions+for+homeless+youth%3A+a+systematic+review.&amp;aulast=Altena&amp;pid=%3Cauthor%3EAltena+AM%3C%2Fauthor%3E%3CAN%3E20494240%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0749379710002114/1-s2.0-S0749379710002114-main.pdf?_tid=8f094182-167e-11e5-b495-00000aab0f6c&amp;acdnat=1434717032_7a3cc424c8e711fcb180f22190a80930
VL  - 38
ER  -
TY  - JOUR
AB  - **Background** 
Mood and anxiety disorders. and problems with self-harm are significant and serious issues that are common in young people in the Criminal Justice System. 

**Aims** 
To examine whether interventions relevant to young offenders with mood or anxiety disorders, or problems with self-harm are effective. Method Systematic review and meta-analysis of data from randomised controlled trials relevant to young offenders experiencing these problems. 

**Results** 
An exhaustive search of the worldwide literature (published and unpublished) yielded 10 studies suitable for inclusion in this review. Meta-analysis of data from three studies (with a total population of 171 individuals) revealed that group-based Cognitive Behaviour Therapy (CBT) may help to reduce symptoms of depression in young offenders 

**Conclusions** 
These preliminary findings suggest that group-based CBT may be useful for young offenders with such mental health problems, but larger high quality RCTs are now needed to bolster the evidence-base. 

(C) 2009 The Association for Professionals in Services for Adolescents. 
Published by Elsevier Ltd. All rights reserved.
AD  - [Townsend, Ellen; Sargeant, Sally; Stocker, Olivia] Univ Nottingham, Sch Psychol, Risk Anal Social Proc &amp; Hlth Grp, Nottingham NG7 2RD, England. [Walker, Dawn-Marie; Sithole, Jabulani] Univ Nottingham, Trent RDSU, Nottingham NG7 2RD, England. [Vostanis, Panos] Univ Leicester, Dept Hlth Sci, Leicester LE1 6TP, Leics, England. [Hawton, Keith] Univ Oxford, Ctr Suicide Res, Dept Psychiat, Warneford Hosp, Oxford OX3 7JX, England. Townsend, E (reprint author), Univ Nottingham, Sch Psychol, Risk Anal Social Proc &amp; Hlth Grp, Univ Pk, Nottingham NG7 2RD, England.
AN  - WOS:000275621500002
AU  - Townsend,
AU  - E.
AU  - Walker,
AU  - D.
AU  - M.
AU  - Sargeant,
AU  - S.
AU  - Vostanis,
AU  - P.
AU  - Hawton,
AU  - K.
AU  - Stocker,
AU  - O.
AU  - Sithole,
AU  - J.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.adolescence.2009.05.015
J2  - J. Adolesc.
KW  - Young offender Juvenile delinquent Mood disorder Anxiety disorder Attempted suicide Self-harm Systematic review Interventions RANDOMIZED CONTROLLED-TRIALS MENTAL-HEALTH JUVENILE-DELINQUENTS DEPRESSION ADOLESCENTS QUALITY YOUTH NEEDS PSYCHOPATHOLOGY STAT
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 569SP Times Cited: 13 Cited Reference Count: 39 Townsend, Ellen Walker, Dawn-Marie Sargeant, Sally Vostanis, Panos Hawton, Keith Stocker, Olivia Sithole, Jabulani 13 ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD LONDON J ADOLESCENCE
PY  - 2010
SP  - 9-20
T2  - Journal of Adolescence
TI  - Systematic review and meta-analysis of interventions relevant for young offenders with mood disorders, anxiety disorders, or self-harm
UR  - &lt;Go to ISI&gt;://WOS:000275621500002http://ac.els-cdn.com/S0140197109000761/1-s2.0-S0140197109000761-main.pdf?_tid=6ce4585e-165a-11e5-9e60-00000aab0f02&amp;acdnat=1434701513_79c334895327726feaa8b524c790ae77
VL  - 33
ER  -
TY  - JOUR
AB  - **Aims:** 
The purpose of this systematic review was to determine if school-based marijuana and alcohol prevention programs are effective in preventing marijuana and alcohol use in adolescents between the ages of 10-15 years. In particular, we examined knowledge versus comprehensive type prevention programs in order to better understand the inconsistency of results in school-based marijuana and alcohol prevention programs found in the literature. 

**Methods:** 
We performed a systematic literature review to identify published or unpublished papers between January 01, 1980 and December 02, 2007 that reviewed the long-term effectiveness (I year or longer) of school-based marijuana and alcohol primary prevention programs targeting adolescents aged 10-15 years. 

**Results:** 
Long-term marijuana and alcohol prevention programs that utilized a &quot;comprehensive&quot; program content resulted in: (a) a mean absolute reduction of 12 days of alcohol usage per month and (b) a mean absolute reduction of 7 days of marijuana usage per month among adolescents aged 10-15 years old. In comparison, school-based marijuana and alcohol prevention programs that utilized &quot;knowledge only&quot; program content resulted in a mean absolute decrease of 2 days of alcohol usage per month among adolescents aged 10-15 years old. Only one study used knowledge-based content and marijuana use as an outcome measure and as such statistical pooling was not possible. 

**Conclusions:** 
The most effective primary prevention programs for reducing marijuana and alcohol use among adolescents aged 10-15 years in the long-term were comprehensive programs that included anti-drug information combined with refusal skills, self-management skills and social-skills training.
AD  - [Lemstra, Mark; Bennett, Norman; Nannapaneni, Ushasri; Neudorf, Cory; Warren, Lynne; Kershaw, Tanis; Scott, Christina] Saskatoon Hlth Reg, Publ Hlth, Saskatoon, SK S7L 0Z2, Canada. Lemstra, M (reprint author), Saskatoon Hlth Reg, Publ Hlth, 310 Idylwyld Dr N, Saskatoon, SK S7L 0Z2, Canada. mlemstra@sktc.sk.ca
AN  - WOS:000274514800008
AU  - Lemstra,
AU  - M.
AU  - Bennett,
AU  - N.
AU  - Nannapaneni,
AU  - U.
AU  - Neudorf,
AU  - C.
AU  - Warren,
AU  - L.
AU  - Kershaw,
AU  - T.
AU  - Scott,
AU  - C.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3109/16066350802673224
J2  - Addict. Res. Theory
KW  - Alcohol drinking drugs school health services intervention prevention SUBSTANCE USE PROTECTIVE FACTORS ABUSE PREVENTION DRUG-ABUSE BEHAVIOR RISK CURRICULUM PRESSURE HEALTH YOUTH Substance Abuse Social Issues
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 555ML Times Cited: 14 Cited Reference Count: 35 Lemstra, Mark Bennett, Norman Nannapaneni, Ushasri Neudorf, Cory Warren, Lynne Kershaw, Tanis Scott, Christina 14 TAYLOR &amp; FRANCIS LTD ABINGDON ADDICT RES THEORY
PY  - 2010
SP  - 84-96
T2  - Addiction Research &amp; Theory
TI  - A systematic review of school-based marijuana and alcohol prevention programs targeting adolescents aged 10-15
UR  - &lt;Go to ISI&gt;://WOS:000274514800008http://informahealthcare.com/doi/pdfplus/10.3109/16066350802673224
VL  - 18
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
High rates of emotional distress and depressive symptoms in the community can reflect difficult life events and social circumstances. There is a need for appropriate, low-cost, non-medical interventions for many individuals. Befriending is an emotional support intervention commonly offered by the voluntary sector.

**AIMS: **
To examine the effectiveness of befriending in the treatment of emotional distress and depressive symptoms.

**METHOD: **
Systematic review of randomised trials of interventions focused on providing emotional support to individuals in the community.

**RESULTS:**
Compared with usual care or no treatment, befriending had a modest but significant effect on depressive symptoms in the short term (standardised mean difference SMD = -0.27, 95% CI -0.48 to -0.06, nine studies) and long term (SMD = -0.18, 95% CI -0.32 to -0.05, five studies).

**CONCLUSIONS: **
Befriending has a modest effect on depressive symptoms and emotional distress in varied patient groups. Further exploration of active ingredients, appropriate target populations and optimal methods of delivery is required.
AD  - Mead, Nicola. Research Fellow, NIHR School for Primary Care Research, 5th Floor, Williamson Building, University of Manchester, Oxford Road, Manchester M13 9PL, UK. nicki.mead@manchester.ac.uk.
AN  - 20118451
AU  - Mead,
AU  - N.
AU  - Lester,
AU  - H.
AU  - Chew-Graham,
AU  - C.
AU  - Gask,
AU  - L.
AU  - Bower,
AU  - P.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1192/bjp.bp.109.064089
DP  - Ovid Technologies
J2  - Br J Psychiatry
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Community Mental Health Services/ec [Economics]
KW  - Community Mental Health Services/mt [Methods]
KW  - Cost-Benefit Analysis
KW  - *Depression/th [Therapy]
KW  - Female
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Randomized Controlled Trials as Topic
KW  - *Social Support
KW  - *Stress, Psychological/th [Therapy]
KW  - Treatment Outcome
KW  - Young Adult
L1  - internal-pdf://0088750573/Mead-2010-Effects of befriending on depressive.pdf
LA  - English
M3  - Meta-Analysis
Review
N1  - Mead, NicolaLester, HelenChew-Graham, CarolynGask, LindaBower, PeterComment in: Evid Based Ment Health. 2010 Aug;13(3):94; PMID: 20682834Comment in: Br J Psychiatry. 2010 Sep;197(3):247; author reply 247; PMID: 20807974
PY  - 2010
SP  - 96-101
T2  - British Journal of Psychiatry
TI  - Effects of befriending on depressive symptoms and distress: systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=20118451
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20118451&amp;id=doi:10.1192%2Fbjp.bp.109.064089&amp;issn=0007-1250&amp;isbn=&amp;volume=196&amp;issue=2&amp;spage=96&amp;pages=96-101&amp;date=2010&amp;title=British+Journal+of+Psychiatry&amp;atitle=Effects+of+befriending+on+depressive+symptoms+and+distress%3A+systematic+review+and+meta-analysis.&amp;aulast=Mead&amp;pid=%3Cauthor%3EMead+N%3C%2Fauthor%3E%3CAN%3E20118451%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/FA825A94C8566B3F1A6F24E082A35C17/S0007125000251532a.pdf/div-class-title-effects-of-befriending-on-depressive-symptoms-and-distress-systematic-review-and-meta-analysis-div.pdf
VL  - 196
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Although multiple micronutrient interventions have been shown to benefit children&#039;s intellectual development, a thorough evaluation of the totality of evidence is currently lacking to direct public health policy. 

**OBJECTIVE: **
This study aimed to systematically review the present literature and to quantify the effect of multiple micronutrients on cognitive performance in schoolchildren.&#039;

**METHODS: **
The Institute for Scientific Information Web of Knowledge and local medical databases were searched for trials published from 1970 to 2008. Randomized controlled trials that investigated the effect of &gt; or =3 micronutrients compared with placebo on cognition in healthy children aged 0-18 y were included following protocol. Data were extracted by 2 independent researchers. The cognitive tests used in the trials were grouped into several cognitive domains (eg, fluid and crystallized intelligence), and pooled effect size estimates were calculated per domain. Heterogeneity was explored through sensitivity and meta-regression techniques. 

**RESULTS: **
Three trials were retrieved in children aged &lt;5 y, and 17 trials were retrieved in children aged 5-16 y. For the older children, pooled random-effect estimates for intervention were 0.14 SD (95% CI: -0.02, 0.29; P = 0.083) for fluid intelligence and -0.03 SD (95% CI: -0.21, 0.15; P = 0.74) for crystallized intelligence, both of which were based on 12 trials. Four trials yielded an overall effect of 0.30 SD (95% CI: 0.01, 0.58; P = 0.044) for academic performance. For other cognitive domains, no significant effects were found. 

**CONCLUSIONS: **
Multiple micronutrient supplementation may be associated with a marginal increase in fluid intelligence and academic performance in healthy schoolchildren but not with crystallized intelligence. More research is required, however, before public health recommendations can be given.
AD  - Eilander,Ans. Unilever Research &amp; Development Vlaardingen, Vlaardingen, The Netherlands. ans.eilander@unilever.com
AN  - 19889823
AU  - Eilander,
AU  - A.
AU  - Gera,
AU  - T.
AU  - Sachdev,
AU  - H.
AU  - S.
AU  - Transler,
AU  - C.
AU  - van
AU  - der
AU  - Knaap,
AU  - H.
AU  - C.
AU  - Kok,
AU  - F.
AU  - J.
AU  - Osendarp,
AU  - S.
AU  - J.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3945/ajcn.2009.28376
DP  - Ovid Technologies
J2  - Am J Clin Nutr
KW  - Adolescent Child Child, Preschool *Cognition/de [Drug Effects] *Dietary Supplements Humans *Intelligence Micronutrients/pd [Pharmacology] Multicenter Studies as Topic Patient Selection Placebos Randomized Controlled Trials as Topic Vitamins/pd [Pharmaco
L1  - internal-pdf://1891850052/Eilander-2010-Multiple micronutrient supplemen.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Eilander, Ans Gera, Tarun Sachdev, Harshpal S Transler, Catherine van der Knaap, Henk Cm Kok, Frans J Osendarp, Saskia Jm
PY  - 2010
SP  - 115-30
T2  - American Journal of Clinical Nutrition
TI  - Multiple micronutrient supplementation for improving cognitive performance in children: systematic review of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19889823
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19889823&amp;id=doi:10.3945%2Fajcn.2009.28376&amp;issn=0002-9165&amp;isbn=&amp;volume=91&amp;issue=1&amp;spage=115&amp;pages=115-30&amp;date=2010&amp;title=American+Journal+of+Clinical+Nutrition&amp;atitle=Multiple+micronutrient+supplementation+for+improving+cognitive+performance+in+children%3A+systematic+review+of+randomized+controlled+trials.&amp;aulast=Eilander&amp;pid=%3Cauthor%3EEilander+A%3C%2Fauthor%3E%3CAN%3E19889823%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ajcn.nutrition.org/content/91/1/115.full.pdf
UR  - http://ajcn.nutrition.org/content/91/1/115.full.pdf
VL  - 91
ER  -
TY  - JOUR
AB  - **Background:** 
Aggression is a major public health issue and is integral to several mental health disorders. Antiepileptic drugs may reduce aggression by acting on the central nervous system to reduce neuronal hyper-excitability associated with aggression.

**Objectives:** 
To evaluate the efficacy of antiepileptic drugs in reducing aggression and associated impulsivity.

**Search methods:** 
We searched CENTRAL, MEDLINE, EMBASE, CINAHL, PsycINFO, metaRegister of Controlled Trials (mRCT) and ClinicalTrials.gov to April 2009. We also searched Cochrane Schizophrenia Group&#039;s register of trials on aggression, National Research Record and handsearched for studies.

**Selection criteria:** 
Prospective, placebo-controlled trials of antiepileptic drugs taken regularly by individuals with recurrent aggression to reduce the frequency or intensity of aggressive outbursts.

**Data collection and analysis:** 
Three authors independently selected studies and two authors independently extracted data. We calculated standardised mean differences (SMDs), with odds ratios (ORs) for dichotomous data.

**Main results:** 
Fourteen studies with data from 672 participants met the inclusion criteria. Five different antiepileptic drugs were examined. Sodium valproate/divalproex was superior to placebo for outpatient men with recurrent impulsive aggression, for impulsively aggressive adults with cluster B personality disorders, and for youths with conduct disorder, but not for children and adolescents with pervasive developmental disorder. Carbamazepine was superior to placebo in reducing acts of self-directed aggression in women with borderline personality disorder, but not in children with conduct disorder. Oxcarbazepine was superior to placebo for verbal aggression and aggression against objects in adult outpatients. Phenytoin was superior to placebo on the frequency of aggressive acts in male prisoners and in outpatient men including those with personality disorder, but not on the frequency of &#039;behavioral incidents&#039; in delinquent boys.

**Authors&#039; conclusions:** 
The authors consider that the body of evidence summarised in this review is insufficient to allow any firm conclusion to be drawn about the use of antiepileptic medication in the treatment of aggression and associated impulsivity. Four antiepileptics (valproate/divalproex, carbamazepine, oxcarbazepine and phenytoin) were effective, compared to placebo, in reducing aggression in at least one study, although for three drugs (valproate, carbamazepine and phenytoin) at least one other study showed no statistically significant difference between treatment and control conditions. Side effects were more commonly noted for the intervention group although adverse effects were not well reported. Absence of information does not necessarily mean that the treatment is safe, nor that the potential gains from the medication necessarily balance the risk of an adverse event occurring.&nbsp;Further research is needed.
AN  - CD003499
AU  - Huband,
AU  - N.
AU  - Ferriter,
AU  - M.
AU  - Nathan,
AU  - R.
AU  - Jones,
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003499.pub3
KW  - Aggression [drug effects] [psychology]
KW  - Anger [drug effects]
KW  - Anticonvulsants [adverse effects] [therapeutic use]
KW  - Antisocial Personality Disorder [drug therapy]
KW  - Disruptive, Impulse Control, and Conduct Disorders [drug therapy]
KW  - Hostility
KW  - Medication Adherence
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Child[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Behav
PY  - 2010
T2  - Cochrane Database of Systematic Reviews
TI  - Antiepileptics for aggression and associated impulsivity
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003499.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003499.pub3/asset/CD003499.pdf?v=1&amp;t=iw7ipqql&amp;s=eea257922cdac51b4b658ec480cd360b17249c08
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
to compare efficacy and acceptability of different pharmacotherapeutic agents for treating anxiety disorders in children and adolescents. 

**METHODS: **
A recently conducted Cochrane Review on pharmacotherapy for anxiety disorders in children and adolescents was updated. A mixed treatment comparison meta-analysis using Bayesian Markov Chain Monte Carlo simulation was used to perform the indirect comparison. We calculated relative risk ratios (RR) with 95% credible interval (CrI) using placebo as the common comparator. 

**RESULTS: **
Data were combined from 16 clinical trials that randomized children to six different treatment strategies, including placebo. Fluoxetine, fluvoxamine, paroxetine, sertraline, and venlafaxine were more efficacious than placebo. Venlafaxine was significantly less efficacious than fluvoxamine (RR = 0.60; 95% CrI 0.35-0.95) and paroxetine (RR = 0.65; 95% CrI 0.44-0.93). Fluoxetine, fluvoxamine, paroxetine, and sertraline had higher acceptability profile than placebo. Venlafaxine was less tolerated than fluvoxamine (RR = 0.16; 95% CrI 0.01-0.64), paroxetine (RR = 0.21; 95% CrI 0.05-0.59), and sertraline (RR = 0.31; 95% CrI 0.08-0.83). Fluvoxamine had a higher rate of clinical response and acceptability compared to other treatments in the network, with probability of 47.5% and 50.6% of being the most efficacious and well-tolerated treatment, respectively. 

**CONCLUSION: **
Clinically important differences exist between commonly prescribed pharmacotherapeutic agents for treating anxiety among children in terms of both efficacy and acceptability in favor of fluvoxamine. Fluvoxamine might be the best choice when starting treatment for anxiety disorders among children and adolescents because it has the most favorable balance between benefits and acceptability.
AD  - Uthman,Olalekan A. West Midlands Health Technology Assessment Collaboration, Department of Public Health &amp; Biostatistics, University of Birmingham, Birmingham, UK. a.o.uthman@bham.ac.uk
AN  - 19905879
AU  - Uthman,
AU  - O.
AU  - A.
AU  - Abdulmalik,
AU  - J.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1185/03007990903416853
DP  - Ovid Technologies
J2  - Curr Med Res Opin
KW  - *Anti-Anxiety Agents/tu [Therapeutic Use] *Anxiety/dt [Drug Therapy] Child Female Humans 0 (Anti-Anxiety Agents)
LA  - English
M3  - Comparative Study Meta-Analysis
N1  - Uthman, Olalekan A Abdulmalik, Jibril
PY  - 2010
SP  - 53-9
T2  - Current Medical Research &amp; Opinion
TI  - Comparative efficacy and acceptability of pharmacotherapeutic agents for anxiety disorders in children and adolescents: a mixed treatment comparison meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19905879 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19905879&amp;id=doi:10.1185%2F03007990903416853&amp;issn=0300-7995&amp;isbn=&amp;volume=26&amp;issue=1&amp;spage=53&amp;pages=53-9&amp;date=2010&amp;title=Current+Medical+Research+%26+Opinion&amp;atitle=Comparative+efficacy+and+acceptability+of+pharmacotherapeutic+agents+for+anxiety+disorders+in+children+and+adolescents%3A+a+mixed+treatment+comparison+meta-analysis.&amp;aulast=Uthman&amp;pid=%3Cauthor%3EUthman+OA%3C%2Fauthor%3E%3CAN%3E19905879%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://informahealthcare.com/doi/pdfplus/10.1185/03007990903416853
VL  - 26
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Motivational interviewing (MI) is a treatment approach that has been widely examined as an intervention for tobacco dependence and is recommended in clinical practice guidelines. Previous reviews evaluating the efficacy of MI for smoking cessation noted effects that were modest in magnitude but included few studies. The current study is a comprehensive meta-analysis of MI for smoking cessation. 

 **METHOD:  **
The meta-analysis included 31 controlled trials with an abstinence outcome variable. Studies with nonpregnant (N = 23) and pregnant samples (N = 8) were analyzed separately.

 **RESULTS: ** 
For nonpregnant samples, combined results suggest that MI significantly outperformed comparison conditions at long-term follow-up points (dc = .17). The magnitudes of this result represented a 2.3% difference in abstinence rates between MI and comparison groups. All analyses investigating the impact of moderating participant, intervention, and study design characteristics on outcome were nonsignificant, with the exception of studies including international, non-U.S. samples, which had larger effects overall. Several subgroups of studies had significant combined effect sizes, pointing to potentially promising applications of MI, including studies that had participants with young age, medical comorbidities, low tobacco dependence, and, consistent with clinical practice guidelines, low motivation or intent to quit. Effects were smaller among pregnant samples. In addition, significant combined effect sizes were observed among subgroups of studies that administered less than 1 hr of MI and among studies that reported high levels of treatment fidelity. 

 **CONCLUSIONS: **
The results are interpreted in light of other behavioral approaches to smoking cessation, and the public health implications of the findings are discussed.

Copyright (c) 2010 APA, all rights reserved.
AD  - Hettema,Jennifer E. Department of Psychology, University of Virginia, USA. jhettema@virginia.edu
AN  - 21114344
AU  - Hettema,
AU  - J.
AU  - E.
AU  - Hendricks,
AU  - P.
AU  - S.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/a0021498
DP  - Ovid Technologies
J2  - J Consult Clin Psychol
KW  - Adolescent Adult *Behavior Therapy/mt [Methods] Female Humans *Interviews as Topic Male *Motivation *Smoking Cessation/mt [Methods] *Tobacco Use Disorder/th [Therapy] Treatment Outcome
LA  - English
M3  - Meta-Analysis Review
N1  - Hettema, Jennifer E Hendricks, Peter S
PY  - 2010
SP  - 868-84
T2  - Journal of Consulting &amp; Clinical Psychology
TI  - Motivational interviewing for smoking cessation: a meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=21114344
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21114344&amp;id=doi:10.1037%2Fa0021498&amp;issn=0022-006X&amp;isbn=&amp;volume=78&amp;issue=6&amp;spage=868&amp;pages=868-84&amp;date=2010&amp;title=Journal+of+Consulting+%26+Clinical+Psychology&amp;atitle=Motivational+interviewing+for+smoking+cessation%3A+a+meta-analytic+review.&amp;aulast=Hettema&amp;pid=%3Cauthor%3EHettema+JE%3C%2Fauthor%3E%3CAN%3E21114344%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://psycnet.apa.org/journals/ccp/78/6/868.pdf
VL  - 78
ER  -
TY  - JOUR
AB  - **Background:** 
PTSD is an anxiety disorder related to exposure to a severe psychological trauma. Symptoms include re-experiencing the event, avoidance and arousal as well as distress and impairment resulting from these symptoms.Guidelines suggest a combination of both psychological therapy and pharmacotherapy may enhance treatment response, especially in those with more severe PTSD or in those who have not responded to either intervention alone.

**Objectives:** 
To assess whether the combination of psychological therapy and pharmacotherapy provides a more efficacious treatment for PTSD than either of these interventions delivered separately.Search methods: Searches were conducted on the trial registers kept by the CCDAN group (CCDANCTR-Studies and CCDANCTR-References) to June 2010. The reference sections of included studies and several conference abstracts were also scanned.

**Selection criteria:** 
Patients of any age or gender, with chronic or recent onset PTSD arising from any type of event relevant to the diagnostic criteria were included. A combination of any psychological therapy and pharmacotherapy was included and compared to wait list, placebo, standard treatment or either intervention alone. The primary outcome was change in total PTSD symptom severity. Other outcomes included changes in functioning, depression and anxiety symptoms, suicide attempts, substance use, withdrawal and cost.

**Data collection and analysis:** 
Two or three review authors independently selected trials, assessed their &#039;risk of bias&#039; and extracted trial and outcome data. We used a fixed-effect model for meta-analysis. The relative risk was used to summarise dichotomous outcomes and the mean difference and standardised mean difference were used to summarise continuous measures.

**Main results:** 
Four trials were eligible for inclusion, one of these trials (n =24) was on children and adolescents. All used an SSRI and prolonged exposure or a cognitive behavioural intervention. Two trials compared combination treatment with pharmacological treatment and two compared combination treatment with psychological treatment. Only two trials reported a total PTSD symptom score and these data could not be combined. There was no strong evidence to show if there were differences between the group receiving combined interventions compared to the group receiving psychological therapy (mean difference 2.44, 95% CI -2.87, 7.35 one study, n=65) or pharmacotherapy (mean difference -4.70, 95% CI -10.84 to 1.44; one study, n = 25). Trialists reported no significant differences between combination and single intervention groups in the other two studies. There were very little data reported for other outcomes, and in no case were significant differences reported.

**Authors&#039; conclusions:** 
There is not enough evidence available to support or refute the effectiveness of combined psychological therapy and pharmacotherapy compared to either of these interventions alone. Further large randomised controlled trials are urgently required.
AN  - CD007316
AU  - Hetrick,
AU  - S.
AU  - E.
AU  - Purcell,
AU  - R.
AU  - Garner,
AU  - B.
AU  - Parslow,
AU  - R.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007316
KW  - Child Abuse, Sexual [psychology]
KW  - Clonazepam [therapeutic use]
KW  - Cognitive Therapy [methods]
KW  - Combined Modality Therapy [methods]
KW  - Paroxetine [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Refugees [psychology]
KW  - Serotonin Uptake Inhibitors [therapeutic use]
KW  - Sertraline [therapeutic use]
KW  - Stress Disorders, Post-Traumatic [drug therapy] [therapy]
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Child[checkword]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Depressn
PY  - 2010
T2  - Cochrane Database of Systematic Reviews
TI  - Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007316.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007316.pub2/asset/CD007316.pdf?v=1&amp;t=iw7j5s4i&amp;s=eff4bdd4f622b3d9ffa8cfc696021a590225a98a
ER  -
TY  - JOUR
AB  - **Objective: **
This systematic review examined the effectiveness of school social work practices using meta-analytic techniques. 

**Method: **
Hierarchical linear modeling software was used to calculate overall effect size estimates as well as test for between-study variability. 

**Results: **
A total of 21 studies were included in the final analysis. Unconditional random effects model shows an overall weighted mean effect size estimate of .23 for externalizing problem outcomes and .40 for internalizing problem outcomes; both categories were statistically significant at the p &lt; .05 level. Subgroup analysis for academic outcomes showed mixed results for knowledge, attendance, and grade point average outcome measures. 

**Conclusions: **
Results highlight the positive impact school social workers may have on student emotional, mental, behavioral, and academic outcomes.
AD  - [Franklin, Cynthia] Univ Texas Austin, Sch Social Work, Austin, TX 78712 USA. [Kim, Johnny S.] Univ Kansas, Lawrence, KS 66045 USA. [Tripodi, Stephen J.] Florida State Univ, Tallahassee, FL 32306 USA. Franklin, C (reprint author), Univ Texas Austin, Sch Social Work, 1 Univ Stn D3500, Austin, TX 78712 USA. cfranklin@mail.utexas.edu
AN  - WOS:000270512500001
AU  - Franklin,
AU  - C.
AU  - Kim,
AU  - J.
AU  - S.
AU  - Tripodi,
AU  - S.
AU  - J.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1049731508330224
J2  - Res. Soc. Work. Pract.
KW  - school social work meta-analysis outcome research systematic review BEHAVIOR PROBLEMS STUDENTS PROGRAM COLLABORATION INTERVENTION SERVICES CHILDREN THERAPY FAILURE RISK Social Work
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 503DL Times Cited: 6 Cited Reference Count: 55 Franklin, Cynthia Kim, Johnny S. Tripodi, Stephen J. 6 SAGE PUBLICATIONS INC THOUSAND OAKS RES SOCIAL WORK PRAC
PY  - 2009
SP  - 667-677
T2  - Research on Social Work Practice
TI  - A Meta-Analysis of Published School Social Work Practice Studies 1980-2007
UR  - &lt;Go to ISI&gt;://WOS:000270512500001http://rsw.sagepub.com/content/19/6/667http://rsw.sagepub.com/content/19/6/667.full.pdf
VL  - 19
ER  -
TY  - JOUR
AB  - The current review provides a qualitative assessment of the efficacy of dialectical behaviour therapy (DBT) as adapted for adolescents. 

The aim was to assess the efficacy of DBT compared to usual methods in the treatment of adolescent mental health symptoms, inclusive of suicidal ideation and self-harm. 

Computerised databases including Medline and PsycINFO were accessed and knowledgeable informants in the area of DBT were contacted. Inclusion criteria required the studies to be clinical trials on DBT provided to adolescents. 

Due to the requirements on research design only three studies were appropriate for review. The review focused on quality assessment of the current data, including investigation into the effects of selection bias, confounding variables, outcome measures and measurement errors. 

The data suggest that there is some evidence for DBT being effective in reducing symptoms of mental health, especially those consistent with borderline personality disorder. 

The resultant data, however, are of very poor quality, and as such the review addresses ways to improve the quality of research and offers suggestions for future research. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Quinn, Candice Renee: candice.renee.quinn@gmail.com Quinn, Candice Renee: School of Public Health, University of Sydney, Edward Ford Building, Sydney, NSW, Australia, 2006, candice.renee.quinn@gmail.com Quinn, Candice Renee: School of Public Health, University of Sydney, Sydney, NSW, Australia
AN  - 2010-11584-005
AU  - Quinn,
AU  - C.
AU  - R.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/00049530802315084
DP  - Ovid Technologies
KW  - treatment efficacy, dialectical behavior therapy, adolescents, mental health symptoms *Mental Health *Symptoms *Treatment Effectiveness Evaluation *Dialectical Behavior Therapy Adolescent Development Adolescent Psychotherapy Behavior Therapy &amp; Behavior
LA  - English
M3  - Literature Review
PY  - 2009
SP  - 156-166
T2  - Australian Journal of Psychology
TI  - Efficacy of dialectical behaviour therapy for adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc6&amp;AN=2010-11584-005 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F00049530802315084&amp;issn=0004-9530&amp;isbn=&amp;volume=61&amp;issue=3&amp;spage=156&amp;pages=156-166&amp;date=2009&amp;title=Australian+Journal+of+Psychology&amp;atitle=Efficacy+of+dialectical+behaviour+therapy+for+adolescents.&amp;aulast=Quinn&amp;pid=%3Cauthor%3EQuinn%2C+Candice+Renee%3C%2Fauthor%3E%3CAN%3E2010-11584-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1080/00049530802315084/asset/00049530802315084.pdf?v=1&amp;t=ib3m4gjs&amp;s=156e3ff2c2b6078c35b0bd703c06c199d7836980
VL  - 61
ER  -
TY  - JOUR
AB  - **BACKGROUND:**
The effects of Web- and computer-based smoking cessation programs are inconsistent in randomized controlled trials (RCTs). We evaluated those effects using a meta-analysis. 

**METHODS: **
We searched MEDLINE (PubMed), EMBASE, and the Cochrane Review in August 2008. Two evaluators independently selected and reviewed eligible studies. 

**RESULTS: **
Of 287 articles searched, 22 RCTs, which included 29 549 participants with 16 050 enrolled in Web- or computer-based smoking cessation program groups and 13 499 enrolled in control groups, were included in the final analyses. In a random-effects meta-analysis of all 22 trials, the intervention group had a significant effect on smoking cessation (relative risk [RR], 1.44; 95% confidence interval [CI], 1.27-1.64). Similar findings were observed in 9 trials using a Web-based intervention (RR, 1.40; 95% CI, 1.13-1.72) and in 13 trials using a computer-based intervention (RR, 1.48; 95% CI, 1.25-1.76). Subgroup analyses revealed similar findings for different levels of methodological rigor, stand-alone vs supplemental interventions, type of abstinence rates employed, and duration of follow-up period, but not for adolescent populations (RR, 1.08; 95% CI, 0.59-1.98). 

**CONCLUSION: **
The meta-analysis of RCTs indicates that there is sufficient clinical evidence to support the use of Web- and computer-based smoking cessation programs for adult smokers. [References: 63]
AD  - Myung,Seung-Kwon. Smoking Cessation Clinic, Center for Cancer Prevention and Detection, Division of Cancer Prevention, National Cancer Control Research Institute, National Cancer Center, Goyang, South Korea. msk@ncc.re.kr
AN  - 19468084
AU  - Myung,
AU  - S.
AU  - K.
AU  - McDonnell,
AU  - D.
AU  - D.
AU  - Kazinets,
AU  - G.
AU  - Seo,
AU  - H.
AU  - G.
AU  - Moskowitz,
AU  - J.
AU  - M.
DA  - May 25
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1001/archinternmed.2009.198
DP  - Ovid Technologies
J2  - Arch Intern Med
KW  - *Computer-Assisted Instruction/mt [Methods] Humans *Internet *Randomized Controlled Trials as Topic *Smoking Cessation/mt [Methods]
L1  - internal-pdf://2985463690/Myung-2009-Effects of Web- and computer-based.pdf
LA  - English
M3  - Meta-Analysis Research Support, U.S. Gov&#039;t, P.H.S. Review
N1  - Myung, Seung-Kwon McDonnell, Diana D Kazinets, Gene Seo, Hong Gwan Moskowitz, Joel M Comment in: Arch Intern Med. 2009 Oct 26;169(19):1814; author reply 1814-5; PMID: 19858446 U48/DP000033 (United States NCCDPHP CDC HHS)
PY  - 2009
SP  - 929-37
T2  - Archives of Internal Medicine
TI  - Effects of Web- and computer-based smoking cessation programs: meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19468084
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19468084&amp;id=doi:10.1001%2Farchinternmed.2009.109&amp;issn=0003-9926&amp;isbn=&amp;volume=169&amp;issue=10&amp;spage=929&amp;pages=929-37&amp;date=2009&amp;title=Archives+of+Internal+Medicine&amp;atitle=Effects+of+Web-+and+computer-based+smoking+cessation+programs%3A+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Myung&amp;pid=%3Cauthor%3EMyung+SK%3C%2Fauthor%3E%3CAN%3E19468084%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://archinte.jamanetwork.com/data/Journals/INTEMED/9897/ira90001_929_937.pdf
UR  - https://jamanetwork.com/journals/jamainternalmedicine/articlepdf/773520/ira90001_929_937.pdf
VL  - 169
ER  -
TY  - JOUR
AB  - **Background**
As a result of HIV-related mortalities more than 13 million children under the age of 15 have lost a parent due to HIV and AIDS. There are also many children who have HIV-positive parents or primary caregivers; these children are affected by HIV and AIDS and are potentially vulnerable to HIV transmission. Children affected by HIV and AIDS are more vulnerable and face greater challenges to their psychosocial well-being compared to other children of the same age. Interventions have been adopted with the aim of improving the psychosocial well-being of children affected by HIV and AIDS. 

**Objectives **
The primary objective of this review was to assess the effectiveness of interventions that aim to improve the psychosocial well-being of children directly affected by HIV and AIDS. 

**Search strategy **
Electronic databases were systematically searched using pre-defined search terms. Internet searches of relevant organizations involved in HIV and AIDS work were conducted and experts in the field and were contacted directly. Searches were conducted between January and September 2008. 

**Selection criteria **
Randomised controlled trials, crossover trials, cluster-randomised trials and factorial trials were eligible for inclusion. If no controlled trials were found, data from well-designed non-randomised intervention studies (such as before and after studies), cohort, and case-control observational studies were considered for inclusion. Studies which included male and female children under the age of 18 years of age, either orphaned due to AIDS (one or more parents died of HIV related-illness or AIDS), or vulnerable children (one or more parents living with HIV or AIDS) were eligible for review. Interventions that aim to improve the psychosocial well-being of children affected by HIV and AIDS were included in the review. This included psychological therapy, psychosocial support and/or care, medical interventions and social interventions. Psychosocial outcomes were defined as any intervention that measures psychological and/or social factors. 

**Data collection and analysis **
Two of the authors independently screened the results of the search. The full text of all potentially relevant studies were obtained and were independently assessed by the two reviewers using pre-determined criteria. 

**Main results **
No studies of interventions for improving the psychosocial well-being of children affected by HIV and AIDS were identified. 

**Authors&#039; conclusions **
Current practice is based on anecdotal knowledge, descriptive studies and situational analyses. Such studies do not provide a strong evidence base for the effectiveness of these interventions. 

**Implications for research **
This systematic review has identified the need for high quality intervention studies. In order to increase the quality and quantity of such studies there is a need for greater partnerships between program implementers and researchers. Implications for practice In the absence of rigorous intervention studies, the body of knowledge available consists of &quot;lessons learned,&quot; child psychological theory and other related research in the adult population. However, such knowledge should not replace the urgent need for rigorous monitoring and evaluation of existing programs and intervention studies to ensure evidence-based practice and policy, and prevent subjecting children to interventions which show no benefit or interventions that could unintentionally lead to harm.
AD  - [King, Evelyn; De Silva, Mary; Patel, Vikram] Univ London London Sch Hyg &amp; Trop Med, Nutr &amp; Publ Hlth Intervent Res Unit, London WC1E 7HT, England. [Stein, Alan] Univ Oxford, Oxford, England. King, E (reprint author), Univ London London Sch Hyg &amp; Trop Med, Nutr &amp; Publ Hlth Intervent Res Unit, Keppel St, London WC1E 7HT, England. eobirikorang@hotmail.com
AN  - WOS:000265200000064
AU  - King,
AU  - E.
AU  - De
AU  - Silva,
AU  - M.
AU  - Stein,
AU  - A.
AU  - Patel,
AU  - V.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD006733.pub2
J2  - Cochrane Database Syst Rev.
KW  - SUB-SAHARAN AFRICA ORPHAN CARE RURAL ZIMBABWE INFECTION HIV/AIDS UGANDA EDUCATION EPIDEMIC PATTERNS FAMILIES Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 433JL Times Cited: 22 Cited Reference Count: 41 King, Evelyn De Silva, Mary Stein, Alan Patel, Vikram 23 JOHN WILEY &amp; SONS LTD CHICHESTER COCHRANE DB SYST REV
PY  - 2009
SP  - 19
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for improving the psychosocial well-being of children affected by HIV and AIDS
UR  - &lt;Go to ISI&gt;://WOS:000265200000064http://onlinelibrary.wiley.com/store/10.1002/14651858.CD006733.pub2/asset/CD006733.pdf?v=1&amp;t=ib7tuf7w&amp;s=94d0189fa21ad23323c358b87e2e291bab19d609
ER  -
TY  - JOUR
AB  - **Objectives:** 
This report presents a systematic review and meta-analysis of the effectiveness of programs designed to reduce school bullying perpetration and victimization (i.e. being bullied). The authors indicate the pitfalls of previous reviews and explain in detail how the present systematic review and meta-analysis addresses the gaps in the existing literature on bullying prevention. 

**Search Strategy:** 
In the present report, we go beyond previous reviews by: doing much more extensive searches for evaluations such as hand-searching all volumes of 35 journals from 1983 up to the end of May 2009; searching for international evaluations in 18 electronic databases and in languages other than English; and focusing only on programs that are specifically designed to reduce bullying and not aggressive behavior (i.e. the outcome variables specifically measure bullying). Leading researchers in the area of school bullying were also contacted via -mail. 

**Selection Criteria:** 
Studies were included in this review if they evaluated the effects of an anti-bullying program by comparing an experimental group who received the intervention with a control group who did not. The word &lsquo;experimental&rsquo; here refers to students who received the program and does not necessarily imply randomization. Four types of research design were included: a) randomized experiments, ) experimental-control comparisons with before and after measures of bullying, ) other experimenta lcontrol comparisons and ) quasi-experimental age-cohort designs, where students of age after the intervention were compared with students of the same age in the same school before the intervention. Both published and unpublished (e.g. PhD theses) reports were included. Reports concerning an evaluation of a program had to clearly indicate that bullying or victimization were included as outcome measures. Bullying and victimization could be measured using self-report questionnaires, peer ratings, teacher ratings, or observational data. 

**Results:**
We found a total of 622 reports that were concerned with bullying prevention. The number of reports on anti-bullying programs and on the necessity of tackling bullying has increased considerably over time. Only 89 of these reports (describing 53 different program evaluations) could be included in our review. Of the 53 different program evaluations, only 44 provided data that permitted the calculation of an effect size for bullying or victimization. Our meta-analysis of these 44 evaluations showed that, overall, school-based anti-bullying programs are effective in reducing bullying and victimization (being bullied). On average, bullying decreased by 20% &ndash; 23% and victimization decreased by 17% &ndash; 20%. The effects were generally highest in the age-cohort designs and lowest in the randomized experiments. It was not clear, however, that the randomized experiments were methodologically superior in all cases, because sometimes a very small number of schools (between three and seven) were randomly assigned to conditions, and because of other methodological problems such as differential attrition. Various program elements and intervention components were associated with a decrease in both bullying and victimization. Work with peers was associated with an increase in victimization. We received feedback from researchers about our coding of 40 out of 44 programs. Analyses of publication bias show that the observed effect sizes (for both bullying and victimization) were based on an unbiased set of studies. 

**Authors&#039; Conclusions:**
Results obtained so far in evaluations of anti-bullying programs are encouraging. The time is ripe to mount a new long-term research strategy on the effectiveness of these programs, based on our findings. The main policy implication of our review is 7 School-Based Programs to Reduce Bullying and Victimization that new anti-bullying programs should be designed and tested based on the key program elements and evaluation components that we have found to be most effective. We recommend that a system of accrediting anti-bullyin pro rams should be developed, supervised by an international body such as the International Observatory on Violence in Schools.
AU  - Farrington,
AU  - D.
AU  - Ttofi,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2009.6
KW  - Bullying
KW  - Education
KW  - Schoolchildren
PY  - 2009
T2  - Campbell Systematic Reviews
TI  - School-Based Programs to Reduce Bullying and Victimization
ER  -
TY  - JOUR
AB  - **Background:** 
Anxiety disorders are a potentially disabling group of disorders which are prevalent in childhood and adolescence. The recognition of the early onset of anxiety disorders, and their successful treatment with medication in adults, has led to the growing interest in using medication for paediatric anxiety disorders.

**Objectives:** 
To assess the efficacy and tolerability of medication for treating paediatric anxiety disorders.

**Search methods:** 
We searched the Cochrane Depression, Anxiety &amp; Neurosis Group specialised register (CCDANCTR-Studies), MEDLINE (via PubMed 1966 to August 2008), EMBASE (1966 to August 2008), and PsycINFO (1972 to August 2008). Various electronic registers were searched for unpublished studies. Reference lists of retrieved articles were searched for additional studies.

**Selection criteria:** 
All randomised controlled trials (RCTs) of pharmacotherapy in childhood/adolescent anxiety disorders.

**Data collection and analysis:** 
Two raters independently assessed RCTs for inclusion in the review, collated trial data, and assessed trial quality. Investigators were contacted to obtain missing data. Summary statistics were stratified by medication class, and by medication agent for the selective serotonin reuptake inhibitors (SSRIs). Dichotomous and continuous measures were calculated using a random effects model, heterogeneity was assessed, and subgroup/sensitivity analyses were undertaken.

**Main results:** 
22 short-term (&lt;= 16 weeks) RCTs were included in the analysis (2519 participants). The majority of the trials assessed the efficacy of the SSRIs (N = 15).Medication and placebo response occurred in 58.1% and 31.5% of patients, respectively (Number of studies (N) = 14, Number needed to treat (NNT) = 4). Medication was more effective than placebo in reducing overall symptom severity in OCD in a post-hoc comparison (N = 7, Weighted Mean Difference (WMD) = -4.45, 95%CI = -5.94, -2.97, n = 765). Medication was less well tolerated than placebo overall, though the absolute proportion of participants who withdrew due to drug-related adverse events was low (4.9%).

**Authors&#039; conclusions:** 
Medication treatments can be effective in paediatric anxiety disorders, acting to reduce core symptoms, and should be considered as part of the treatment of these disorders. The greatest number of trials showing efficacy to date have assessed the SSRIs in treating paediatric OCD.There is no clear evidence to show that any particular class of medication is more effective or better tolerated than any other. As quantitative data was only available for the SSRIs and venlafaxine the routine use of benzodiazepines cannot be recommended, especially given concerns of dependency and treatment -related emergent adverse events associated with this class of drugs.Future RCTs could help identify potential clinical moderators of treatment efficacy. Studies of the long-term efficacy of medication treatment, optimal dosage, as well as direct comparisons of pharmacotherapy and psychotherapy are also warranted.
AN  - CD005170
AU  - Ipser,
AU  - J.
AU  - C.
AU  - Stein,
AU  - D.
AU  - J.
AU  - Hawkridge,
AU  - S.
AU  - Hoppe,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd005170.pub2
KW  - Anxiety Disorders [drug therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Serotonin Uptake Inhibitors [therapeutic use]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2009
T2  - Cochrane Database of Systematic Reviews
TI  - Pharmacotherapy for anxiety disorders in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005170.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005170.pub2/asset/CD005170.pdf?v=1&amp;t=iw7knh1o&amp;s=73389e2789acf6d6a2b0c5762b4cd924d0531861
ER  -
TY  - JOUR
AB  - **Background **
The onset of depression during adolescence can adversely impact future functioning. Cognitive-Behavioural Therapy (CBT) has been suggested to prevent depression in adolescence by providing an individual with the ability to interpret and the tools to deal with the impact of negative life events. 

**Objective **
Examine the best available evidence to determine the effectiveness of CBT to prevent the onset of depression in young people, and assess whether the incorporation of hopeful elements makes CBT more effective. 

**Search strategy **
A comprehensive three-step search strategy was developed to find both published and unpublished studies in English from 1987 to March 2007. Papers selected for retrieval were then assessed for methodological validity by two independent reviewers. 

**Selection criteria **
Papers that used a randomised controlled design and investigated the efficacy of CBT to prevent the onset of depression in young people between the age of 10 years and 16 years were included. Papers were included if the CBT involved between four and 15 sessions, a follow-up period of between 3 and 24 months and included typical strategies, such as the identification of negative and irrational beliefs, the establishment of links between thoughts, feelings and behaviours, and provided tools so participants could self-monitor these. 

**Data analysis **
Data were extracted using the standard tool from the Joanna Briggs Institute, pooled in a meta-analysis, and then grouped and analysed according to the amount of hopeful elements the CBT was judged to contain. 

**Results and conclusion **
Limited evidence was found to indicate that CBT, regardless of its content (i.e. with or without hopeful elements), is effective at preventing the onset of clinical levels of depression in young people on a sustained basis. Nonetheless, given the devastating impact that depression can have on young people&#039;s future functioning, further research is needed to develop effective interventions to equip young people with the cognitive skills to buffer its onset on a more sustained basis and to enable them to reach and sustain mental health.

Copyright &copy; 2009 The Authors. Journal Compilation &copy; Blackwell Publishing Asia Pty Ltd.
AD  - Venning,Anthony. School of Psychology and Discipline of Nursing, The University of Adelaide, Cancer Council Australia, Adelaide, South Australia, Australia.
AN  - 21631843
AU  - Venning,
AU  - A.
AU  - Kettler,
AU  - L.
AU  - Eliott,
AU  - J.
AU  - Wilson,
AU  - A.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/j.1744-1609.2009.00122.x
DP  - Ovid Technologies
J2  - Int
L1  - internal-pdf://0257254338/Venning-2009-The effectiveness of Cognitive-Be.pdf
LA  - English
N1  - Venning, Anthony Kettler, Lisa Eliott, Jaklin Wilson, Anne
PY  - 2009
SP  - 15-33
T2  - International Journal of Evidence-Based Healthcare
TI  - The effectiveness of Cognitive-Behavioural Therapy with hopeful elements to prevent the development of depression in young people: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=21631843
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:21631843&amp;id=doi:10.1111%2Fj.1744-1609.2009.00122.x&amp;issn=1744-1595&amp;isbn=&amp;volume=7&amp;issue=1&amp;spage=15&amp;pages=15-33&amp;date=2009&amp;title=International+Journal+of+Evidence-Based+Healthcare&amp;atitle=The+effectiveness+of+Cognitive-Behavioural+Therapy+with+hopeful+elements+to+prevent+the+development+of+depression+in+young+people%3A+a+systematic+review.&amp;aulast=Venning&amp;pid=%3Cauthor%3EVenning+A%3C%2Fauthor%3E%3CAN%3E21631843%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://graphics.tx.ovid.com/ovftpdfs/FPDDNCLBMEJCKF00/fs046/ovft/live/gv023/01258363/01258363-200903000-00003.pdf
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCDCKGDIMI00/fs046/ovft/live/gv023/01258363/01258363-200903000-00003.pdf
VL  - 7
ER  -
TY  - JOUR
AB  - The &quot;Coping with Depression&quot; course (CWD) is by the far the best studied psychoeducational intervention for the treatment and prevention of depression, and is used in routine practice in several countries. 

The CWD is a highly structured cognitive-behavioral intervention, which has been adapted for several goals, contexts, and target populations. The efficacy of the CWD has been examined in 25 randomized controlled trials. We conducted a meta-analysis of these studies. 

The 6 studies aimed at the prevention of new cases of major depression were found to result in a reduced risk of getting major depression of 38% (incidence rate ratio was 0.62). The 18 studies examining the CWD as a treatment of depression found a mean effect size (Cohen&#039;s d) of 0.28. 

Direct comparisons with other psychotherapies did not result in any indication that the CWD was less efficacious. The CWD is a flexible treatment which can easily be adapted for different populations and this may have led researchers to use this intervention for complex target groups, which in turn may have resulted in a lower mean effect size. The CWD has contributed considerably to the development and innovation of prevention and treatment of depression in many target populations. 

(C) 2009 Elsevier Ltd. All rights reserved.
AD  - [Cuijpers, Pim] Vrije Univ Amsterdam, Dept Clin Psychol, NL-1081 BT Amsterdam, Netherlands. [Cuijpers, Pim] Vrije Univ Amsterdam, EMGO Inst, NL-1081 BT Amsterdam, Netherlands. [Munoz, Ricardo F.] Univ Calif San Francisco, Dept Psychiat, San Francisco Gen Hosp, San Francisco, CA 94143 USA. [Clarke, Gregory N.] Kaiser Permanente Ctr Hlth Res, Portland, OR USA. [Lewinsohn, Peter M.] Oregon Res Inst, Eugene, OR 97403 USA. Cuijpers, P (reprint author), Vrije Univ Amsterdam, Dept Clin Psychol, Boechorststr 1, NL-1081 BT Amsterdam, Netherlands. p.cuijpers@psy.vu.nl
AN  - WOS:000267638900005
AU  - Cuijpers,
AU  - P.
AU  - Munoz,
AU  - R.
AU  - F.
AU  - Clarke,
AU  - G.
AU  - N.
AU  - Lewinsohn,
AU  - P.
AU  - M.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2009.04.005
J2  - Clin. Psychol. Rev.
KW  - Depression Psychoeducation Cognitive behavior therapy Systematic review COGNITIVE-BEHAVIORAL TREATMENT RANDOMIZED CONTROLLED-TRIAL DISSEMINATING QUALITY IMPROVEMENT PUERTO-RICAN ADOLESCENTS PRIMARY-CARE PSYCHOLOGICAL TREATMENT SMOKING-CESSATION SUBTHRES
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 466CS Times Cited: 68 Cited Reference Count: 77 Cuijpers, Pim Munoz, Ricardo F. Clarke, Gregory N. Lewinsohn, Peter M. Cuijpers, Pim/G-1703-2013 70 PERGAMON-ELSEVIER SCIENCE LTD OXFORD CLIN PSYCHOL REV
PY  - 2009
SP  - 449-458
T2  - Clinical Psychology Review
TI  - Psychoeducational treatment and prevention of depression: The &quot;coping with depression&quot; course thirty years later
UR  - &lt;Go to ISI&gt;://WOS:000267638900005http://ac.els-cdn.com/S027273580900049X/1-s2.0-S027273580900049X-main.pdf?_tid=2849fa30-1972-11e5-8ad4-00000aab0f02&amp;acdnat=1435041559_3ddd239f01b4403b76345b7ed5547aae
VL  - 29
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
There is accumulating evidence that recurring pain symptoms in children are becoming a serious health concern. Children and adolescents who suffer from ongoing pain have negative outcomes not only to their physical health, but also to their emotional and spiritual health. Furthermore, recurrent pain in children may also cause a number of other negative consequences to the child, the family and society. Thus, a non-pharmacological approach to reduce the pain is vital to help children having better quality of life. 

**OBJECTIVES: **
The objective of this review is to determine the best available evidence on the effectiveness of non-pharmacological pain management in relieving chronic pain for children and adolescents. 

**SEARCH STRATEGY: **
The search strategy aimed to find published studies, between 1956 and 2008 and limited to the English or Chinese languages. Reference lists of studies that met the inclusion criteria were searched for additional studies. 

**TYPES OF STUDIES: **
This review included any systematic reviews, randomized controlled trials and quasi-experimental design that explored the effectiveness of non-pharmacological intervention for chronic pain in children and adolescents. 

**TYPES OF PARTICIPANTS: **
Children and adolescents with cancer pain, Juvenile chronic arthritis, sickle cell disease, burn pain, chronic or recurrent abdominal pain, headache and aged 18 years old or less and suffering with pain for at least one month. 

**TYPES OF INTERVENTIONS: **
The review considered studies that examined non-pharmacological interventions in relieving chronic pain for children and adolescents that included heat wrap therapy, massage, chiropractic spinal manipulative therapy, cognitive-behavioral therapy (distraction &amp; guided imagery), meditation, progressive muscle relaxation, self-hypnosis, biofeedback, music therapy, and dance training. 

**TYPES OF OUTCOME MEASURES: **
The primary outcome measures included: (1) Behavioral variables, such as pain behavior, cognitive coping and appraisal, psychiatric reaction (anxiety and depression), and social activities, (2) Quality of life scores and (3) Pain scores. 

**TYPES OF SETTING: **
The review focuses on studies that operated either at a hospital or in a community setting. 

**DATA COLLECTION AND ANALYSIS: **
Meta-analysis was used to pool the data from studies to determine the effectiveness of the intervention. The Comprehensive Meta Analysis V2 was used to manage the data. 

**RESULTS: **
The search process identified 43,100 studies that addressed the objectives of the review protocol. Fifty-four articles were selected for critical appraisal. Finally, 31 trials were considered to be eligible for the present review and 5 articles were excluded. Data was pooled together from eight articles using meta-analysis to examine the effectiveness of relaxation training of the pre-test and post-test of headache intensity. The findings show that the effective size was 0.323 with significant difference. Two of the articles evaluate the effectiveness of relaxation training for releasing the recurrent headaches for adolescents and the post-test data were collected over the following six months. The findings show that there is a statistically significance difference. Another two articles examined the effectiveness of a relaxation training program in reducing the sum of medication used of adolescents with recurrent headaches. The findings show that there is no statistical significance. Furthermore, the findings show that biofeedback treatment could improve the outcome of children and adolescents&#039; headache, especially at 6 and 12 months after the treatment. In terms of psychosocial treatment, five articles examined the effectiveness of behavioral treatment, relaxation training program, cognitive behavior therapy, and acupuncture/ hypnosis intervention to reduce anxiety of children and adolescent with chronic pain. The various outcomes measures among the five studies.

**CONCLUSIONS: **
This review has provided an evidence-based guide to future priorities for clinical practice. Relaxation programs could reduce recurrent headache and pain intensity in children and adolescents in the short term as well as lasting for three and six months. Furthermore, biofeedback treatment could reduce recurrent headache of pain intensity in children and adolescents in the short term and last for as long as six months.
AD  - Mu, Pei-Fan. 1. School of Nursing, National Yang-Ming University, 2. Department of Nursing, Veteran General Hospital, Taipei, Taiwan R. O. C.
AN  - 27820170
AU  - Mu,
AU  - P.
AU  - F.
AU  - Chen,
AU  - Y.
AU  - C.
AU  - Cheng,
AU  - S.
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.11124/01938924-200907340-00001
DP  - Ovid Technologies
J2  - JBI Libr Syst Rev
L1  - internal-pdf://2229504755/Mu-2009-The effectiveness of non-pharmacologic.pdf
LA  - English
N1  - Mu, Pei-Fan Chen, Yu-Chih Cheng, Shu-Chen 01938924-200907340-00001
PY  - 2009
SP  - 1489-1543
T2  - JBI Library of Systematic Reviewis
TI  - The effectiveness of non-pharmacological pain management in relieving chronic pain for children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=27820170http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:27820170&amp;id=doi:&amp;issn=1838-2142&amp;isbn=&amp;volume=7&amp;issue=34&amp;spage=1489&amp;pages=1489-1543&amp;date=2009&amp;title=JBI+Library+of+Systematic+Reviewis&amp;atitle=The+effectiveness+of+non-pharmacological+pain+management+in+relieving+chronic+pain+for+children+and+adolescents.&amp;aulast=Mu&amp;pid=%3Cauthor%3EMu+PF%3C%2Fauthor%3E%3CAN%3E27820170%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 7
ER  -
TY  - JOUR
AB  - This review aimed to gain insight in the extent to which psychosocial effects of obesity prevention programmes have been studied, to give an overview of the methods used to measure the particular psychosocial aspects and - if possible - to quantify the effects found. 

Intervention studies (n = 267) covering the period 1990-October 2005 were derived from seven reviews about childhood obesity interventions. An additional search identified 2754 studies covering the period January 2005-February 2008. In total, 2901 papers (excluding 120 duplicates) were screened for inclusion. 

Sixty-nine papers covering 53 interventions were included and screened on measuring psychosocial variables. All original authors were contacted. Seven of the selected interventions measured psychosocial variables, five of which evaluated a net intervention effect as compared with a control condition. 

Only two interventions reported a statistically significant net intervention effect (a decrease in use of purging or diet pills and a decrease in peer ratings of aggression and observed verbal aggression). 

We conclude that a minority of childhood obesity interventions investigate the effects of their programmes on psychosocial well-being of children and adolescents. It is recommended that in the future, these programmes will be evaluated in a uniform way on a broad range of psychosocial aspects 

&copy; 2009 International Association for the Study of Obesity.
AD  - (Van Wijnen, Wendel-Vos, Wammes, Bemelmans) Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, BA Bilthoven, Netherlands (Wendel-Vos) National Institute for Public Health and the Environment, Centre for Prevention and Health Services Research, PO Box 1, 3720 BA Bilthoven, Netherlands G. C. W. Wendel-Vos, National Institute for Public Health and the Environment, Centre for Prevention and Health Services Research, PO Box 1, 3720 BA Bilthoven, Netherlands. E-mail: Wanda.Vos@rivm.nl
AU  - Van
AU  - Wijnen,
AU  - L.
AU  - G.
AU  - C.
AU  - Wendel-Vos,
AU  - G.
AU  - C.
AU  - W.
AU  - Wammes,
AU  - B.
AU  - M.
AU  - Bemelmans,
AU  - W.
AU  - J.
AU  - E.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1467-789X.2008.00549.x
DP  - Ovid Technologies DUI - 2009205832
KW  - Children Overweight Psychosocial well-being Review aggression body image child child behavior child health care child psychology childhood disease/pc [Prevention] childhood disease/th [Therapy] dietary intake education program feeding behavior fitness h
L1  - internal-pdf://1502951648/Wijnen-2009-The impact of school-based prevent.pdf
LA  - English
M3  - Review
PY  - 2009
SP  - 298-312
T2  - Obesity Reviews
TI  - The impact of school-based prevention of overweight on psychosocial well-being of children: Obesity Prevention
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed9&amp;AN=2009205832 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1111%2Fj.1467-789X.2008.00549.x&amp;issn=1467-7881&amp;isbn=&amp;volume=10&amp;issue=3&amp;spage=298&amp;pages=298-312&amp;date=2009&amp;title=Obesity+Reviews&amp;atitle=The+impact+of+school-based+prevention+of+overweight+on+psychosocial+well-being+of+children%3A+Obesity+Prevention&amp;aulast=Van+Wijnen&amp;pid=%3Cauthor%3EVan+Wijnen+L.G.C.%3C%2Fauthor%3E%3CAN%3E2009205832%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1467-789X.2008.00549.x/asset/j.1467-789X.2008.00549.x.pdf?v=1&amp;t=ib7jadgs&amp;s=3ecce19c6a7dfb87dd1e67a3d9314230067c79d1
UR  - http://onlinelibrary.wiley.com/store/10.1111/j.1467-789X.2008.00549.x/asset/j.1467-789X.2008.00549.x.pdf?v=1&amp;t=j8ygfzi8&amp;s=58c98469b4efb8c20f7c0202539ff86afe836e6c
VL  - 10
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Although the efficacy of meditation interventions has been examined among adult samples, meditation treatment effects among youth are relatively unknown. We systematically reviewed empirical studies for the health-related effects of sitting-meditative practices implemented among youth aged 6 to 18 years in school, clinic, and community settings. 

**METHODS: **
A systematic review of electronic databases (PubMed, Ovid, Web of Science, Cochrane Reviews Database, Google Scholar) was conducted from 1982 to 2008, obtaining a sample of 16 empirical studies related to sitting-meditation interventions among youth. 

**RESULTS: **
Meditation modalities included mindfulness meditation, transcendental meditation, mindfulness-based stress reduction, and mindfulness-based cognitive therapy. Study samples primarily consisted of youth with preexisting conditions such as high-normal blood pressure, attention-deficit/hyperactivity disorder, and learning disabilities. Studies that examined physiologic outcomes were composed almost entirely of African American/black participants. Median effect sizes were slightly smaller than those obtained from adult samples and ranged from 0.16 to 0.29 for physiologic outcomes and 0.27 to 0.70 for psychosocial/behavioral outcomes. 

**CONCLUSIONS: **
Sitting meditation seems to be an effective intervention in the treatment of physiologic, psychosocial, and behavioral conditions among youth. Because of current limitations, carefully constructed research is needed to advance our understanding of sitting meditation and its future use as an effective treatment modality among younger populations. 

Pediatrics 2009; 124: e532-e541
AD  - [Black, David S.; Milam, Joel; Sussman, Steve] Univ So Calif, Inst Hlth Promot &amp; Dis Prevent Res, Keck Sch Med, Alhambra, CA 91803 USA. Black, DS (reprint author), Univ So Calif, Inst Hlth Promot &amp; Dis Prevent Res, Keck Sch Med, 1000 S Fremont Ave,Unit 8,Bldg A-5,Suite 5228, Alhambra, CA 91803 USA. davidbla@usc.edu
AN  - WOS:000269383100044
AU  - Black,
AU  - D.
AU  - S.
AU  - Milam,
AU  - J.
AU  - Sussman,
AU  - S.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1542/peds.2008-3434
J2  - Pediatrics
KW  - literature review meditation mindfulness children adolescents youth efficacy AMBULATORY BLOOD-PRESSURE TRANSCENDENTAL-MEDITATION MINDFULNESS MEDITATION STRESS REDUCTION PSYCHOSOCIAL STRESS SELF-REPORT PSYCHOTHERAPY METAANALYSIS ADOLESCENTS IMPACT Pediat
L1  - internal-pdf://1948471435/Black-2009-Sitting-Meditation Interventions Am.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 488XH Times Cited: 28 Cited Reference Count: 63 Black, David S. Milam, Joel Sussman, Steve Emidio, Fernando/H-2015-2011 National Institute of Drug Abuse [R01 DA020138]; National Cancer Institute [T32 CA09492] The National Institute of Drug Abuse grant R01 DA020138 and National Cancer Institute grant T32 CA09492 supported the preparation of this article. We thank some of the authors of the studies cited in this article for their help in responding to our inquiries and providing us with unpublished data. 28 AMER ACAD PEDIATRICS ELK GROVE VILLAGE PEDIATRICS
PY  - 2009
SP  - E532-E541
T2  - Pediatrics
TI  - Sitting-Meditation Interventions Among Youth: A Review of Treatment Efficacy
UR  - &lt;Go to ISI&gt;://WOS:000269383100044http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195513/pdf/nihms310813.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195513/pdf/nihms310813.pdf
VL  - 124
ER  -
TY  - JOUR
AB  - **Background: **
Children with Fetal Alcohol Spectrum Disorders (FASD) may have significant neurobehavioural problems persisting into adulthood. Early diagnosis may decrease the risk of adverse life outcomes. However, little is known about effective interventions for children with FASD. Our aim is to conduct a systematic review of the literature to identify and evaluate the evidence for pharmacological and non-pharmacological interventions for children with FASD. 

**Methods: **
We did an electronic search of the Cochrane Library, MEDLINE, EMBASE, PsychINFO, CINAHL and ERIC for clinical studies (Randomized controlled trials (RCT), quasi RCT, controlled trials and pre- and post-intervention studies) which evaluated pharmacological, behavioural, speech therapy, occupational therapy, physiotherapy, psychosocial and educational interventions and early intervention programs. Participants were aged under 18 years with a diagnosis of a FASD. Selection of studies for inclusion and assessment of study quality was undertaken independently by two reviewers. Meta-analysis was not possible due to diversity in the interventions and outcome measures. 

**Results: **
Twelve studies met the inclusion criteria. Methodological weaknesses were common, including small sample sizes; inadequate study design and short term follow up. Pharmacological interventions, evaluated in two studies (both RCT) showed some benefit from stimulant medications. Educational and learning strategies (three RCT) were evaluated in seven studies. There was some evidence to suggest that virtual reality training, cognitive control therapy, language and literacy therapy, mathematics intervention and rehearsal training for memory may be beneficial strategies. Three studies evaluating social communication and behavioural strategies (two RCT) suggested that social skills training may improve social skills and behaviour at home and Attention Process Training may improve attention. 

**Conclusion: **
There is limited good quality evidence for specific interventions for managing FASD, however seven randomized controlled trials that address specific functional deficits of children with FASD are underway or recently completed.
AD  - [Peadon, Elizabeth; Rhys-Jones, Biarta; Elliott, Elizabeth J.] Univ Sydney, Discipline Paediat &amp; Child Hlth, Sydney, NSW 2006, Australia. [Peadon, Elizabeth; Elliott, Elizabeth J.] Australian Paediat Surveillance Unit, Sydney, NSW, Australia. [Peadon, Elizabeth; Elliott, Elizabeth J.] Childrens Hosp Westmead, Sydney, NSW, Australia. [Bower, Carol] Univ Western Australia, Ctr Child Hlth Res, Telethon Inst Child Hlth Res, Perth, WA 6009, Australia. Peadon, E (reprint author), Univ Sydney, Discipline Paediat &amp; Child Hlth, Sydney, NSW 2006, Australia. elizabp5@chw.edu.au; apsu@chw.edu.au; carolb@ichr.uwa.edu.au; elizabe2@chw.ed.au
AN  - WOS:000267989300001
AU  - Peadon,
AU  - E.
AU  - Rhys-Jones,
AU  - B.
AU  - Bower,
AU  - C.
AU  - Elliott,
AU  - E.
AU  - J.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/1471-2431-9-35
J2  - BMC Pediatr.
KW  - PRENATAL ALCOHOL INTERNATIONAL PERSPECTIVE EXPOSURE PREGNANCY DIAGNOSIS KNOWLEDGE BEHAVIOR DEFICITS OUTCOMES SAFETY Pediatrics
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 470PT Times Cited: 15 Cited Reference Count: 38 Peadon, Elizabeth Rhys-Jones, Biarta Bower, Carol Elliott, Elizabeth J. National Health and Medical Research Council (NH MRC) [003209, 353514]; NH&amp; MRC Fellowships [172303, 353625, 457084]; NH&amp; MRC Postgraduate Scholarship [457230]; Department of Health and Ageing; Faculty of Medicine at the University of Sydney; NH MRC Enabling [402784] Paula Cronin assisted in the original review design and Ruth Mitchell assisted with the search strategy. Drug and Alcohol Services, South Australia supported this review financially. We acknowledge the National Health and Medical Research Council (NH&amp; MRC) Program Grants 003209 and 353514; NH&amp; MRC Fellowships (CB) 172303 and 353625 and (EE) 457084; and NH&amp; MRC Postgraduate Scholarship (EP) 457230 for financial support. The Australian Paediatric Surveillance Unit is a Unit of the Division of Paediatrics and Child Health, Royal Australasian College of Physicians and is funded by the Department of Health and Ageing, the Faculty of Medicine at the University of Sydney, and an NH&amp; MRC Enabling Grant, 402784. 17 BIOMED CENTRAL LTD LONDON BMC PEDIATR
PY  - 2009
SP  - 9
T2  - Bmc Pediatrics
TI  - Systematic review of interventions for children with Fetal Alcohol Spectrum Disorders
UR  - &lt;Go to ISI&gt;://WOS:000267989300001http://www.biomedcentral.com/content/pdf/1471-2431-9-35.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
To determine the impact on teenage pregnancy of interventions that address the social disadvantage associated with early parenthood and to assess the appropriateness of such interventions for young people in the United Kingdom.

**DESIGN: **
Systematic review, including a statistical meta-analysis of controlled trials on interventions for early parenthood and a thematic synthesis of qualitative studies that investigated the views on early parenthood of young people living in the UK. 

**DATA SOURCES: **
12 electronic bibliographic databases, five key journals, reference lists of relevant studies, study authors, and experts in the field. Review methods Two independent reviewers assessed the methodological quality of studies and abstracted data. 

**RESULTS: **
Ten controlled trials and five qualitative studies were included. Controlled trials evaluated either early childhood interventions or youth development programmes. The overall pooled effect size showed that teenage pregnancy rates were 39% lower among individuals receiving an intervention than in those receiving standard practice or no intervention (relative risk 0.61; 95% confidence interval 0.48 to 0.77). Three main themes associated with early parenthood emerged from the qualitative studies: dislike of school; poor material circumstances and unhappy childhood; and low expectations for the future. Comparison of these factors related to teenage pregnancy with the content of the programmes used in the controlled trials indicated that both early childhood interventions and youth development programmes are appropriate strategies for reducing unintended teenage pregnancies. The programmes aim to promote engagement with school through learning support, ameliorate unhappy childhood through guidance and social support, and raise aspirations through career development and work experience. However, none of these approaches directly tackles all the societal, community, and family level factors that influence young people&#039;s routes to early parenthood. 

**CONCLUSIONS: **
A small but reliable evidence base supports the effectiveness and appropriateness of early childhood interventions and youth development programmes for reducing unintended teenage pregnancy. Combining the findings from both controlled trials and qualitative studies provides a strong evidence base for informing effective public policy.
AD  - Harden,Angela. Institute of Health and Human Development, University of East London, London, E15 4LZ. a.harden@uel.ac.uk
AN  - 19910400
AU  - Harden,
AU  - A.
AU  - Brunton,
AU  - G.
AU  - Fletcher,
AU  - A.
AU  - Oakley,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmj.b4254
DP  - Ovid Technologies
J2  - Bmj
KW  - Adolescent Adolescent Health Services/og [Organization &amp; Administration] Attitude to Health Child Child Health Services/og [Organization &amp; Administration] Controlled Clinical Trials as Topic Data Collection Female Humans Male Pregnancy *Pregnancy in Ado
L1  - internal-pdf://0357759900/Harden-2009-Teenage pregnancy and social disad.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Harden, Angela Brunton, Ginny Fletcher, Adam Oakley, Ann bmj.b4254 (United Kingdom Department of Health)
PY  - 2009
SP  - b4254
T2  - BMJ
TI  - Teenage pregnancy and social disadvantage: systematic review integrating controlled trials and qualitative studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19910400 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19910400&amp;id=doi:10.1136%2Fbmj.b4254&amp;issn=0959-535X&amp;isbn=&amp;volume=339&amp;issue=12&amp;spage=b4254&amp;pages=b4254&amp;date=2009&amp;title=BMJ&amp;atitle=Teenage+pregnancy+and+social+disadvantage%3A+systematic+review+integrating+controlled+trials+and+qualitative+studies.&amp;aulast=Harden&amp;pid=%3Cauthor%3EHarden+A%3C%2Fauthor%3E%3CAN%3E19910400%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776931/pdf/bmj.b4254.pdf
UR  - http://www.bmj.com/content/bmj/339/bmj.b4254.full.pdf
VL  - 339
ER  -
TY  - JOUR
AB  - **Background:** 
It is estimated that more than 20% of pregnant women worldwide consume alcohol. Current research suggests that alcohol intake of seven or more standard drinks (one standard drink = 13.6 grams of absolute alcohol) per week during pregnancy places the baby at risk of serious, lifelong developmental and cognitive disabilities. Psychological and educational interventions may help women to reduce their alcohol intake during pregnancy.

**Objectives:** 
To determine the effectiveness of psychological and educational interventions to reduce alcohol consumption during pregnancy in pregnant women or women planning pregnancy.

**Search methods:** 
We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (August 2008), CENTRAL (The Cochrane Library 2007, Issue 4), MEDLINE (1966 to November 2007), EMBASE (1980 to November 2007), CINAHL (1982 to November 2007), Counsel.Lit (1980 to November 2007), PsycLIT (1974 to November 2007) and PsycINFO (1967 to November 2007) and checked cited references from retrieved articles.

**Selection criteria:** 
Randomized controlled trials examining the effectiveness of psychological and educational interventions for reducing consumption of alcohol among pregnant women, or women planning for pregnancy.

**Data collection and analysis:** 
At least two review authors independently extracted information from the results sections of the included studies.

**Main results:** 
Four studies met the inclusion criteria (715 pregnant women), and reported on at least one of the outcomes of interest. We performed no meta-analyses as the interventions and outcomes measured in the studies were not sufficiently similar. For most outcomes there were no significant differences between groups; and results relating to abstaining or reducing alcohol consumption were mixed. Results from individual studies suggest that interventions may encourage women to abstain from alcohol in pregnancy. There was very little information provided on the effects of interventions on the health of mothers and babies.

**Authors&#039; conclusions:** 
The evidence from the limited number of studies suggests that psychological and educational interventions may result in increased abstinence from alcohol, and a reduction in alcohol consumption among pregnant women. However, results were not consistent, and the paucity of studies, the number of total participants, the high risk of bias of some of the studies, and the complexity of interventions limits our ability to determine the type of intervention which would be most effective in increasing abstinence from, or reducing the consumption of, alcohol among pregnant women.
AN  - CD004228
AU  - Stade,
AU  - B.
AU  - C.
AU  - Bailey,
AU  - C.
AU  - Dzendoletas,
AU  - D.
AU  - Sgro,
AU  - M.
AU  - Dowswell,
AU  - T.
AU  - Bennett,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004228.pub2
KW  - Alcohol Drinking [adverse effects] [prevention &amp; control]
KW  - Counseling [methods]
KW  - Ethanol [poisoning]
KW  - Fetal Alcohol Spectrum Disorders [prevention &amp; control]
KW  - Preconception Care
KW  - Pregnancy Complications [prevention &amp; control]
KW  - Psychotherapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Pregnancy[checkword]
KW  - Preg
PY  - 2009
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological and/or educational interventions for reducing alcohol consumption in pregnant women and women planning pregnancy
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004228.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004228.pub2/asset/CD004228.pdf?v=1&amp;t=iw7ksgv4&amp;s=188a981d6aa4246f1dc83626c51a5cff6b7264b3
ER  -
TY  - JOUR
AB  - The Picture Exchange Communication System (PECS) is a communication program that has become widely used, especially with children with autism. 

This paper reports the results of a review of the empirical literature on PECS. A descriptive review is provided of the 27 studies identified, which included randomized controlled trials (RCTs), other group designs and single subject studies. 

For 10 appropriate single subject designs the percentage of nonoverlapping data (PND) and percentage exceeding median (PEM) metrics were examined. While there are few RCTs, on balance, available research provides preliminary evidence that PECS is readily learned by most participants and provides a means of communication for individuals with little or no functional speech. 

Very limited data suggest some positive effect on both social-communicative and challenging behaviors, while effects on speech development remain unclear. 

Directions for future research are discussed including the priority need for further well-conducted RCTs.
AD  - [Preston, Deborah; Carter, Mark] Macquarie Univ, Special Educ Ctr, Sydney, NSW 2109, Australia. Carter, M (reprint author), Macquarie Univ, Special Educ Ctr, Sydney, NSW 2109, Australia. mark.carter@mq.edu.au
AN  - WOS:000269917900010
AU  - Preston,
AU  - D.
AU  - Carter,
AU  - M.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10803-009-0763-y
J2  - J. Autism Dev. Disord.
KW  - Picture exchange communication system Augmentative and alternative communication Autism SINGLE-SUBJECT RESEARCH SEVERE DEVELOPMENTAL-DISABILITIES AUTISM SPECTRUM DISORDERS QUANTITATIVE SYNTHESIS ALTERNATIVE COMMUNICATION FUNCTIONAL COMMUNICATION SPEECH
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 495TM Times Cited: 38 Cited Reference Count: 84 Preston, Deborah Carter, Mark 39 SPRINGER/PLENUM PUBLISHERS NEW YORK J AUTISM DEV DISORD
PY  - 2009
SP  - 1471-1486
T2  - Journal of Autism and Developmental Disorders
TI  - A Review of the Efficacy of the Picture Exchange Communication System Intervention
UR  - &lt;Go to ISI&gt;://WOS:000269917900010
UR  - https://link.springer.com/article/10.1007%2Fs10803-009-0763-y
VL  - 39
ER  -
TY  - JOUR
AB  - **Objectives:** 
To examine the effectiveness of cyber abuse interventions in increasing Internet safety knowledge and decreasing risky online behaviour. The scope of this review is experimental and quasi-experimental prevention and intervention strategies that target children ages 5 to 19 years old and/or their parents, utilize a control group, and examine an outcome related to cyber abuse such as Internet safety knowledge, risky online behaviour, or exposure to inappropriate online content. 

**Selection Criteria:** 
The scope of this review is experimental and quasi-experimental prevention and intervention strategies that target children ages 5 to 19 years old and/or their parents, utilize a control group, and examine an outcome related to cyber abuse such as Internet safety knowledge, risky online behaviour, or exposure to inappropriate online content. 

**Search Strategy:** 
We searched the following databases : Psychological Abstracts (PsycINFO, PsycLIT, ClinPsyc-clinical subset) ; MEDLINE; EMBASE; Database of reviews of effectiveness (DARE online); ChildData (child health and welfare); ASSIA (applied social sciences); Caredata (social work); Social Work Abstracts; Child Abuse, Child Welfare &amp; Adoption; Cochrane Collaboration ; C2-SPECTR; Social Sciences Abstracts; Social Service Abstracts; Dissertation Abstracts International (DAI). We also handsearched Youth and Society; Journal of Interpersonal Violence; Annual Review of Sex; Computers in Human Behavior; Computers &amp; Education; and Journal of Adolescent Health. Additionally, we contacted experts in the field and searched for grey literature. 

**Data Collection and Analysis:**
Two screeners reviewed abstracts and full-text of all articles. Three articles met all inclusion criteria, and effect sizes and z-tests were calculated for all relevant outcomes. 

**Main Results:** 
Significantz -tests were found between pre-and post-test scores on measures related to Internet safety knowledge such as managing online risk and identifying online predators. Most -tests related to pre- and post- measures of risky online behaviour were not significant, including disclosing one&rsquo;s name, participating in open chat rooms, or emailing strangers. 

**Reviewers&#039; Conclusionss:** 
Results provide evidence that participation in psychoeducational Internet safety interventions is associated with an increase in Internet safety knowledge but is not significantly associated with a change in risky online behaviour. The need for further research in this field is highlighted.
AU  - Mishna,
AU  - F.
AU  - Cook,
AU  - C.
AU  - MacFadden,
AU  - R.
AU  - Saini,
AU  - M.
AU  - Wu,
AU  - M.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2009.2
KW  - Risk prevention
KW  - Adolescents
KW  - Children (age group)
KW  - Abuse
KW  - Computer networks
PY  - 2009
T2  - Campbell Systematic Reviews
TI  - Interventions for Children, Youth, and Parents to Prevent and Reduce Cyber Abuse
ER  -
TY  - JOUR
AB  - Students with emotional and behavioral disorders (EBD) often engage in behavior that is disruptive in the classroom, impedes educational progress, and inhibits peer relationships. Video modeling has been demonstrated to be an effective intervention for other challenging populations (e.g., autism) and has been identified as a feasible intervention within schools. This review examined the efficacy of video modeling as an intervention for students with EBD. The sixteen studies included are evaluated in terms of participants, intervention procedures, dependent variables, and results. Studies are categorized and discussed according to the behavior targeted for intervention (i.e., increasing peer interaction, increasing on-task behavior, and decreasing inappropriate behavior). Results suggest that video modeling is an effective intervention for each of these target behaviors. However, gaps in the research (e.g., limited social validity data) exist and warrant future research. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Baker, Sonia D.: sbaker@mail.utexas.edu Baker, Sonia D.: University of Texas at Austin, 1 University Station. D 5300, Austin, TX, US, 78712, sbaker@mail.utexas.edu Baker, Sonia D.: The Meadows Center for Preventing Educational Risk, University of Texas at Austin, Austin, TX, US Lang, Russell: The Meadows Center for Preventing Educational Risk, University of Texas at Austin, Austin, TX, US O&#039;Reilly, Mark: The Meadows Center for Preventing Educational Risk, University of Texas at Austin, Austin, TX, US
AN  - 2009-12256-003
AU  - Baker,
AU  - S.
AU  - D.
AU  - Lang,
AU  - R.
AU  - O&#039;Reilly,
AU  - M.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Har ikke DOI og har ikke lenke
DP  - Ovid Technologies
KW  - video modeling, students, emotional disorders, behavioral disorders, disruptive classroom behavior *Behavior Disorders *Classroom Behavior *Classroom Environment *Emotional Disturbances Students Classroom Dynamics &amp; Student Adjustment &amp; Attitudes [3560]
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2009
SP  - 403-420
T2  - Education and Treatment of Children
TI  - Review of video modeling with students with emotional and behavioral disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc6&amp;AN=2009-12256-003 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1353%2Fetc.0.0065&amp;issn=0748-8491&amp;isbn=&amp;volume=32&amp;issue=3&amp;spage=403&amp;pages=403-420&amp;date=2009&amp;title=Education+%26+Treatment+of+Children&amp;atitle=Review+of+video+modeling+with+students+with+emotional+and+behavioral+disorders.&amp;aulast=Baker&amp;pid=%3Cauthor%3EBaker%2C+Sonia+D%3C%2Fauthor%3E%3CAN%3E2009-12256-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://muse.jhu.edu/login?auth=0&amp;type=summary&amp;url=/journals/education_and_treatment_of_children/v032/32.3.baker.htmlhttp://muse.jhu.edu/journals/education_and_treatment_of_children/v032/32.3.baker.pdf
VL  - 32
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To determine in a systematic review, whether interventions for infant development that involve parents, improve neurodevelopment at 12 months corrected age or older.

**STUDY DESIGN: **
Randomized trials were identified where an infant intervention was aimed to improve development and involved parents of preterms; and long-term neurodevelopment using standardized tests at 12 months (or longer) was reported. 

**RESULT: **
Identified studies (n=25) used a variety of interventions including parent education, infant stimulation, home visits or individualized developmental care. Meta-analysis at 12 months (N=2198 infants) found significantly higher mental (N=2198) and physical (N=1319) performance scores favoring the intervention group. At 24 months, the mental (N=1490) performance scores were improved, but physical (N=1025) performance scores were not statistically significant. The improvement in neurodevelopmental outcome was not sustained at 36 months (N=961) and 5 years (N=1017). 

**CONCLUSION: **
Positive clinically meaningful effects (&gt;5 points) are seen to an age of 36 months, but are no longer present at 5 years. [References: 81]
AD  - Vanderveen,J A. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada.
AN  - 19148113
AU  - Vanderveen,
AU  - J.
AU  - A.
AU  - Bassler,
AU  - D.
AU  - Robertson,
AU  - C.
AU  - M.
AU  - Kirpalani,
AU  - H.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1038/jp.2008.229
DP  - Ovid Technologies
J2  - J Perinatol
KW  - *Child Development/ph [Physiology] Developmental Disabilities/pp [Physiopathology] *Developmental Disabilities/pc [Prevention &amp; Control] *Developmental Disabilities/th [Therapy] *Early Intervention (Education) Female Follow-Up Studies Humans Infant Infa
L1  - internal-pdf://3448678903/Vanderveen-2009-Early interventions involving.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Vanderveen, J A Bassler, D Robertson, C M T Kirpalani, H
PY  - 2009
SP  - 343-51
T2  - Journal of Perinatology
TI  - Early interventions involving parents to improve neurodevelopmental outcomes of premature infants: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19148113
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19148113&amp;id=doi:10.1038%2Fjp.2008.229&amp;issn=0743-8346&amp;isbn=&amp;volume=29&amp;issue=5&amp;spage=343&amp;pages=343-51&amp;date=2009&amp;title=Journal+of+Perinatology&amp;atitle=Early+interventions+involving+parents+to+improve+neurodevelopmental+outcomes+of+premature+infants%3A+a+meta-analysis.&amp;aulast=Vanderveen&amp;pid=%3Cauthor%3EVanderveen+JA%3C%2Fauthor%3E%3CAN%3E19148113%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.nature.com/jp/journal/v29/n5/pdf/jp2008229a.pdf
UR  - http://www.nature.com/jp/journal/v29/n5/pdf/jp2008229a.pdf
VL  - 29
ER  -
TY  - JOUR
AB  - The efficacy of eye movement desensitization and reprocessing (EMDR) in children with post-traumatic stress symptoms was meta-analytically examined from the perspective of incremental efficacy. 

Overall post-treatment effect size for EMDR was medium and significant (d=.56). 

Results indicate efficacy of EMDR when effect sizes are based on comparisons between the EMDR and the non-established trauma treatment or the no-treatment control groups, and the incremental efficacy when effect sizes are based on comparisons between the EMDR and the established (CBT) trauma treatment. 

The discussion focuses on the future replication of EMDR findings and further research on post-traumatic stress in children.
AD  - Rodenburg,Roos. Department of Educational Sciences, University of Amsterdam, The Netherlands. rrodenburg@sein.nl
AN  - 19616353
AU  - Rodenburg,
AU  - R.
AU  - Benjamin,
AU  - A.
AU  - de
AU  - Roos,
AU  - C.
AU  - Meijer,
AU  - A.
AU  - M.
AU  - Stams,
AU  - G.
AU  - J.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2009.06.008
DP  - Ovid Technologies
J2  - Clin Psychol Rev
KW  - Child Cognitive Therapy Controlled Clinical Trials as Topic *Eye Movement Desensitization Reprocessing Female Follow-Up Studies Humans Male Sex Factors Stress Disorders, Post-Traumatic/di [Diagnosis] Stress Disorders, Post-Traumatic/px [Psychology] *Str
LA  - English
M3  - Comparative Study Meta-Analysis
N1  - Rodenburg, Roos Benjamin, Anja de Roos, Carlijn Meijer, Ann Marie Stams, Geert Jan
PY  - 2009
SP  - 599-606
T2  - Clinical Psychology Review
TI  - Efficacy of EMDR in children: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19616353 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19616353&amp;id=doi:10.1016%2Fj.cpr.2009.06.008&amp;issn=0272-7358&amp;isbn=&amp;volume=29&amp;issue=7&amp;spage=599&amp;pages=599-606&amp;date=2009&amp;title=Clinical+Psychology+Review&amp;atitle=Efficacy+of+EMDR+in+children%3A+a+meta-analysis.&amp;aulast=Rodenburg&amp;pid=%3Cauthor%3ERodenburg+R%3C%2Fauthor%3E%3CAN%3E19616353%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735809000890/1-s2.0-S0272735809000890-main.pdf?_tid=66d973e8-1972-11e5-8308-00000aab0f26&amp;acdnat=1435041664_a04bd6bfa1252d2ec1a066952596c973
VL  - 29
ER  -
TY  - JOUR
AB  - **Background:** 
Current policy in the UK and elsewhere places emphasis on the provision of mental health services in the least restrictive setting, whilst also recognising that some children will require inpatient care. As a result, there are a range of mental health services to manage young people with serious mental health problems who are at risk of being admitted to an inpatient unit in community or outpatient settings.

**Objectives:** 
1. To assess the effectiveness, acceptability and cost of mental health services that provide an alternative to inpatient care for children and young people. 2. To identify the range and prevalence of different models of service that seek to avoid inpatient care for children and young people.

**Search methods:** 
Our search included the Cochrane Effective Practice and Organisation of Care Group Specialised Register (2007), the Cochrane Central Register of Controlled Trials (The Cochrane Library 2006, issue 4), MEDLINE (1966 to 2007), EMBASE (1982 to 2006), the British Nursing Index (1994 to 2006), RCN database (1985 to 1996), CINAHL (1982 to 2006) and PsycInfo (1972 to 2007).

**Selection criteria:** 
Randomised controlled trials of mental health services providing specialist care, beyond the scope of generic outpatient provision, as an alternative to inpatient mental health care, for children or adolescents aged from five to 18 years who have a serious mental health condition requiring specialist services beyond the capacity of generic outpatient provision. The control group received mental health services in an inpatient or equivalent setting.

**Data collection and analysis:** 
Two authors independently extracted data and assessed study quality. We grouped studies according to the intervention type but did not pool data because of differences in the interventions and measures of outcome. Where data were available we calculated confidence intervals (CIs) for differences between groups at follow up. We also calculated standardised mean differences (SMDs) and 95% CIs for each outcome in terms of mean change from baseline to follow up using the follow-up SDs. We calculated SMDs (taking into account the direction of change and the scoring of each instrument) so that negative SMDs indicate results that favour treatment and positive SMDs favour the control group.

**Main results:** 
We included seven randomised controlled trials (recruiting a total of 799 participants) evaluating four distinct models of care: multi-systemic therapy (MST) at home, specialist outpatient service, intensive home treatment and intensive home-based crisis intervention (&#039;Homebuilders&#039; model for crisis intervention). Young people receiving home-based MST experienced some improved functioning in terms of externalising symptoms and they spent fewer days out of school and out-of-home placement. At short term follow up the control group had a greater improvement in terms of adaptability and cohesion; this was not sustained at four months follow up. There were small, significant patient improvements reported in both groups in the trial evaluating the intensive home-based crisis intervention using the &#039;Homebuilders&#039; model. No differences at follow up were reported in the two trials evaluating intensive home treatment, or in the trials evaluating specialist outpatient services.

**Authors&#039; conclusions:** 
The quality of the evidence base currently provides very little guidance for the development of services. If randomised controlled trials are not feasible then consideration should be given to alternative study designs, such as prospective systems of audit conducted across several centres, as this has the potential to improve the current level of evidence. These studies should include baseline measurement at admission along with demographic data, and outcomes measured using a few standardised robust instruments.
AN  - CD006410
AU  - Shepperd,
AU  - S.
AU  - Doll,
AU  - H.
AU  - Gowers,
AU  - S.
AU  - James,
AU  - A.
AU  - Fazel,
AU  - M.
AU  - Fitzpatrick,
AU  - R.
AU  - Pollock,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd006410.pub2
KW  - Ambulatory Care [methods]
KW  - Community Mental Health Services [methods] [organization &amp; administration]
KW  - Crisis Intervention [methods]
KW  - Family Therapy [methods] [organization &amp; administration]
KW  - Home Care Services
KW  - Mental Disorders [therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Epoc
PY  - 2009
T2  - Cochrane Database of Systematic Reviews
TI  - Alternatives to inpatient mental health care for children and young people
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006410.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006410.pub2/asset/CD006410.pdf?v=1&amp;t=iw7lhyjr&amp;s=3755f95f2ab73eb76e6989a33b093798a10e7654
ER  -
TY  - JOUR
AB  - **Objective **
To review the effectiveness of applied behavior intervention (ABI) programs for preschool children with autism spectrum disorder (ASD) in their cognitive, adaptive behavior, and language development. 

**Study design **
Systematic reviews, randomized or quasirandomized controlled trials (RCT) of ABI delivered to preschool children with ASD were reviewed. Quantitative data on cognitive, language, and behavior outcomes were extracted and pooled for meta-analysis (RevMan 4.2). 

**Results **
Thirteen studies met the inclusion criteria. Six of these were randomized comparison trials with adequate methodologic quality (PEDro &gt;= 6). Meta-analysis of 4 studies concluded that, compared with standard care, ABI programs did not significantly improve the cognitive outcomes of children in the experimental group who scored a standardized mean difference (SMD) of 0.38 (950/CI -0.09 to 0.84; P = .1). There was no additional benefit over standard care for expressive language; SMD of 0.37 (95%CI -0.09 to 0.84; P = .11), for receptive language; SMD of 0.29 (95%CI -0.17 to 0.74; P = .22) or adaptive behavior; SMD of 0.30 (95%CI -0.1.6 to 0.77: P = .20). 

**Conclusions** 
Currently there is inadequate evidence that ABI has better outcomes than standard care for children with autism. Appropriately powered clinical trials with broader outcomes are required. 

(J Pediatr 2009;154:338-44)
AD  - [Spreckley, Michele] Royal Childrens Hosp, Uncle Bobs Child Dev Ctr, Dept Dev Med, Melbourne, Vic, Australia. [Boyd, Roslyn] Murdoch Childrens Res Inst, Melbourne, Vic, Australia. [Boyd, Roslyn] Univ Queensland, Queensland Cerebral Palsy &amp; Rehabil Res Ctr, Dept Paediat &amp; Child Hlth, Fac Med, Brisbane, Qld, Australia. Spreckley, M (reprint author), Uncle Bobs Child Dev Ctr, 56 Chapman St, Melbourne, Vic 3051, Australia. michele.spreckley@rch.org.au
AN  - WOS:000264166100010
AU  - Spreckley,
AU  - M.
AU  - Boyd,
AU  - R.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.jpeds.2008.09.012
J2  - J. Pediatr.
KW  - RANDOMIZED CONTROLLED-TRIAL YOUNG-CHILDREN DISORDERS PROGRAM PREVALENCE SPECTRUM Pediatrics
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 418RM Times Cited: 41 Cited Reference Count: 38 Spreckley, Michele Boyd, Roslyn Boyd, Roslyn/A-4498-2011 Boyd, Roslyn/0000-0002-4919-5975 National Health and Medical Research Council [473849]; Department of Innovation, Queensland Supported by a National Health and Medical Research Council Career Development Fellowship (NHMRC 473849), and a Smart State Fellowship from the Department of Innovation, Queensland. The authors declare no potential conflict of interest. 41 MOSBY-ELSEVIER NEW YORK J PEDIATR
PY  - 2009
SP  - 338-344
T2  - Journal of Pediatrics
TI  - Efficacy of Applied Behavioral Intervention in Preschool Children with Autism for Improving Cognitive, Language, and Adaptive Behavior: A Systematic Review and Meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000264166100010http://ac.els-cdn.com/S0022347608007774/1-s2.0-S0022347608007774-main.pdf?_tid=8af901be-1998-11e5-97df-00000aab0f02&amp;acdnat=1435058046_9d36b7551ce8c7caff207017a5ff8692
VL  - 154
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
It is unclear whether the use of selective serotonin reuptake inhibitors (SSRIs) and other antidepressant drugs reduce the risk of suicide in people with depression. We explored the association between exposure to SSRIs and risk of suicide completion or attempt. 

**METHODS: **
We conducted a systematic review of observational studies that reported completed or attempted suicide in depressed individuals who were exposed to SSRIs compared with those who were not exposed to antidepressants. We assessed the overall risk of completed or attempted suicide. 

**RESULTS: **
Eight studies involving more than 200 000 patients with moderate or severe depression were included in the meta-analysis. Although exposure to SSRIs increased the risk of completed or attempted suicide among adolescents (odds ratio [OR] 1.92, 95% confidence interval [CI] 1.51-2.44), the risk was decreased among adults (OR 0.57, 95% CI 0.47-0.70). Among people aged 65 or more years, exposure to SSRIs had a protective effect (OR 0.46, 95% CI 0.27-0.79). Sensitivity analyses did not change these findings. In particular, for studies that used completed suicide as an outcome, exposure to SSRIs was associated with increased risk among adolescents (OR 5.81, 95% CI 1.57-21.51) and decreased risk among adults (OR 0.66, 95% CI 0.52-0.83) and older people (OR 0.53, 95% CI 0.26-1.06). 

**INTERPRETATION: **
Based on data from observational studies, use of SSRIs may be associated with a reduced risk of suicide in adults with depression. Among adolescents, use of SSRIs may increase suicidality.
AD  - Barbui,Corrado. World Health Organization Collaborating Centre for Research and Training in Mental Health, Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy.
AN  - 19188627
AU  - Barbui,
AU  - C.
AU  - Esposito,
AU  - E.
AU  - Cipriani,
AU  - A.
DA  - Feb 3
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1503/cmaj.081514
DP  - Ovid Technologies
J2  - Cmaj
KW  - Adolescent Adolescent Behavior/px [Psychology] Age Factors Confidence Intervals Depression/dt [Drug Therapy] Humans Odds Ratio Risk Assessment *Serotonin Uptake Inhibitors/ae [Adverse Effects] *Suicide 0 (Serotonin Uptake Inhibitors)
L1  - internal-pdf://0176440710/Barbui-2009-Selective serotonin reuptake inhib.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Barbui, Corrado Esposito, Eleonora Cipriani, Andrea Comment in: Ann Intern Med. 2009 Jun 16;150(12):JC6-13; PMID: 19528558 Comment in: CMAJ. 2009 Feb 3;180(3):270-1; PMID: 19188617
PY  - 2009
SP  - 291-7
T2  - CMAJ Canadian Medical Association Journal
TI  - Selective serotonin reuptake inhibitors and risk of suicide: a systematic review of observational studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19188627 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19188627&amp;id=doi:10.1503%2Fcmaj.081514&amp;issn=0820-3946&amp;isbn=&amp;volume=180&amp;issue=3&amp;spage=291&amp;pages=291-7&amp;date=2009&amp;title=CMAJ+Canadian+Medical+Association+Journal&amp;atitle=Selective+serotonin+reuptake+inhibitors+and+risk+of+suicide%3A+a+systematic+review+of+observational+studies.&amp;aulast=Barbui&amp;pid=%3Cauthor%3EBarbui+C%3C%2Fauthor%3E%3CAN%3E19188627%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630355/pdf/20090203s00017p291.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630355/pdf/20090203s00017p291.pdf
VL  - 180
ER  -
TY  - JOUR
AB  - Little is known about the impact of preventive interventions on inequalities in young people&#039;s mental health. 

We conducted a systematic review of mental health promotion interventions based on cognitive behavioural therapy (CBT) delivered in schools to young people aged 11-19. 

Meta-analysis of 17 high quality randomised controlled trials (RCTs) showed a reduction in symptoms of depression, which was generally short term. Interventions for people with clinical risk factors or existing symptoms were more effective, with benefits lasting up to six months. We also found that CBT may be more effective for young people from families with middle to high socioeconomic status (SES) than for those from low SES backgrounds. 

However, this finding was based on a meta-regression with only six studies. A lack of long-term follow-up data and a failure to report subgroup analyses prevented further conclusions being drawn about the effect of these types of interventions on mental health inequalities.
AD  - [Kavanagh, Josephine; Oliver, Sandy; Lorenc, Theo; Caird, Jennifer; Tucker, Helen; Harden, Angela; Greaves, Adele; Thomas, James; Oakley, Ann] Univ London, Social Sci Res Unit, London WC1E 7HU, England. Kavanagh, J (reprint author), Univ London, Social Sci Res Unit, London WC1E 7HU, England.
AN  - WOS:000267412000006
AU  - Kavanagh,
AU  - J.
AU  - Oliver,
AU  - S.
AU  - Lorenc,
AU  - T.
AU  - Caird,
AU  - J.
AU  - Tucker,
AU  - H.
AU  - Harden,
AU  - A.
AU  - Greaves,
AU  - A.
AU  - Thomas,
AU  - J.
AU  - Oakley,
AU  - A.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.5172/hesr.18.1.61
J2  - Health Sociol. Rev.
KW  - Sociology health inequalities mental health young people systematic review research methods TERM FOLLOW-UP ADOLESCENT DEPRESSION CONTROLLED-TRIAL PREVENTION HEALTH UNIVERSAL ADULTHOOD SYMPTOMS CHILDREN PROGRAM Health Policy &amp; Services Sociology
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 463EK Times Cited: 10 Cited Reference Count: 67 Kavanagh, Josephine Oliver, Sandy Lorenc, Theo Caird, Jennifer Tucker, Helen Harden, Angela Greaves, Adele Thomas, James Oakley, Ann 11 ECONTENT MANAGEMENT MALENY HEALTH SOCIOL REV
PY  - 2009
SP  - 61-78
T2  - Health Sociology Review
TI  - School-based cognitive-behavioural interventions: A systematic review of effects and inequalities
UR  - &lt;Go to ISI&gt;://WOS:000267412000006http://www.tandfonline.com/doi/pdf/10.5172/hesr.18.1.61
VL  - 18
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Conduct problems are common, disabling and costly. The prognosis for children with conduct problems is poor, with outcomes in adulthood including criminal behaviour, alcoholism, drug abuse, domestic violence, child abuse and a range of psychiatric disorders. There has been a rapid expansion of group based parent-training programmes for the treatment of children with conduct problems in a number of countries over the past 10 years. Existing reviews of parent training have methodological limitations such as inclusion of non-randomised studies, the absence of investigation for heterogeneity prior to meta-analysis or failure to report confidence intervals. The objective of the current study was to systematically review randomised controlled trials of parenting programmes for the treatment of children with conduct problems. 

**METHODS: **
Standard systematic review methods were followed including duplicate inclusion decisions, data extraction and quality assessment. Twenty electronic databases from the fields of medicine, psychology, social science and education were comprehensively searched for RCTs and systematic reviews to February 2006. Inclusion criteria were: randomised controlled trial; of structured, repeatable parenting programmes; for parents/carers of children up to the age of 18 with a conduct problem; and at least one measure of child behaviour. Meta-analysis and qualitative synthesis were used to summarise included studies. 

**RESULTS: **
57 RCTs were included. Studies were small with an average group size of 21. Meta-analyses using both parent (SMD -0.67; 95% CI: -0.91, -0.42) and independent (SMD -0.44; 95% CI: -0.66, -0.23) reports of outcome showed significant differences favouring the intervention group. There was insufficient evidence to determine the relative effectiveness of different approaches to delivering parenting programmes. 

**CONCLUSION: **
Parenting programmes are an effective treatment for children with conduct problems. The relative effectiveness of different parenting programmes requires further research.
AD  - Dretzke,Janine. Unit of Public Health, Epidemiology and Biostatistics, University of Birmingham, Edgbaston, Birmingham, UK. J.Dretzke@bham.ac.uk
AN  - 19261188
AU  - Dretzke,
AU  - J.
AU  - Davenport,
AU  - C.
AU  - Frew,
AU  - E.
AU  - Barlow,
AU  - J.
AU  - Stewart-Brown,
AU  - S.
AU  - Bayliss,
AU  - S.
AU  - Taylor,
AU  - R.
AU  - S.
AU  - Sandercock,
AU  - J.
AU  - Hyde,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/1753-2000-3-7
DP  - Ovid Technologies
J2  - Child Adolesc Psychiatry Ment Health
LA  - English
N1  - Dretzke, Janine Davenport, Clare Frew, Emma Barlow, Jane Stewart-Brown, Sarah Bayliss, Sue Taylor, Rod S Sandercock, Josie Hyde, Chris
PY  - 2009
SP  - 7
T2  - Child &amp; Adolescent Psychiatry &amp; Mental Health [Electronic Resource]
TI  - The clinical effectiveness of different parenting programmes for children with conduct problems: a systematic review of randomised controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=19261188 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19261188&amp;id=doi:10.1186%2F1753-2000-3-7&amp;issn=1753-2000&amp;isbn=&amp;volume=3&amp;issue=1&amp;spage=7&amp;pages=7&amp;date=2009&amp;title=Child+%26+Adolescent+Psychiatry+%26+Mental+Health+%5BElectronic+Resource%5D&amp;atitle=The+clinical+effectiveness+of+different+parenting+programmes+for+children+with+conduct+problems%3A+a+systematic+review+of+randomised+controlled+trials.&amp;aulast=Dretzke&amp;pid=%3Cauthor%3EDretzke+J%3C%2Fauthor%3E%3CAN%3E19261188%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.capmh.com/content/pdf/1753-2000-3-7.pdf
VL  - 3
ER  -
TY  - JOUR
AB  - **AIM: **
The aim of this study was to review the effects of early developmental intervention after discharge from hospital on motor and cognitive development in preterm infants. 

**METHOD: **
Randomized controlled trials (RCTs) or quasi-RCTs of early developmental intervention programmes for preterm infants in which motor or cognitive outcomes were reported and in which the intervention commenced before or after discharge were included. A systematic review and meta-analysis of studies grouped by intervention, age of outcome, and study quality was undertaken. Databases searched (up to January 2009) included the Cochrane Central Register of Controlled Trials, MEDLINE, CINAHL, PsycINFO, and Embase. 

**RESULTS: **
Eighteen studies met the inclusion criteria (2686 patients randomized), but only 11 studies had data suitable for meta-analysis. Early developmental intervention improved cognitive outcomes at infant age (developmental quotient: standardized mean difference [SMD] 0.42, 95% confidence interval [CI] 0.33-0.52; p&lt;0.001), and at preschool age (IQ: SMD 0.46, 95% CI 0.33-0.59; p&lt;0.001). However, the benefit was not sustained at school age (IQ: SMD 0.02, 95% CI -0.10 to 0.14; p=0.71). Early intervention had little effect on motor outcome at infant or school age, and there was no study reporting motor outcome at preschool age. 

**INTERPRETATION:** 
Current evidence suggests that the benefits of developmental intervention postdischarge are restricted to short-term gains in cognitive outcome.
AD  - Orton,Jane. The Royal Women&#039;s Hospital, Melbourne, Australia. jane.orton@thewomens.org.au
AN  - 19732117
AU  - Orton,
AU  - J.
AU  - Spittle,
AU  - A.
AU  - Doyle,
AU  - L.
AU  - Anderson,
AU  - P.
AU  - Boyd,
AU  - R.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1469-8749.2009.03414.x
DP  - Ovid Technologies
J2  - Dev Med Child Neurol
KW  - Adolescent Child *Child Development/ph [Physiology] Child, Preschool *Cognition/ph [Physiology] *Early Intervention (Education) Humans Infant, Newborn Infant, Premature Infant, Premature, Diseases/pp [Physiopathology] *Infant, Premature, Diseases/px [Ps
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Orton, Jane Spittle, Alicia Doyle, Lex Anderson, Peter Boyd, Roslyn
PY  - 2009
SP  - 851-9
T2  - Developmental Medicine &amp; Child Neurology
TI  - Do early intervention programmes improve cognitive and motor outcomes for preterm infants after discharge? A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19732117 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19732117&amp;id=doi:10.1111%2Fj.1469-8749.2009.03414.x&amp;issn=0012-1622&amp;isbn=&amp;volume=51&amp;issue=11&amp;spage=851&amp;pages=851-9&amp;date=2009&amp;title=Developmental+Medicine+%26+Child+Neurology&amp;atitle=Do+early+intervention+programmes+improve+cognitive+and+motor+outcomes+for+preterm+infants+after+discharge%3F+A+systematic+review.&amp;aulast=Orton&amp;pid=%3Cauthor%3EOrton+J%3C%2Fauthor%3E%3CAN%3E19732117%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1469-8749.2009.03414.x/asset/j.1469-8749.2009.03414.x.pdf?v=1&amp;t=ib7vas7h&amp;s=d3ae5f941906fb1fdc072d5eb576fec548e58e77
VL  - 51
ER  -
TY  - JOUR
AB  - **Background:** 
Attention deficit hyperactivity disorder (ADHD) is increasingly recognised as occurring in people with intellectual disability (ID), although treatment of ADHD in this population has not ben tested widely. Risperidone has been used to treat ADHD in people with ID, although the evidence for its effectiveness is unclear.

**Objectives:**
To examine the effectiveness of risperidone for the treatment of attention deficit hyperactivity disorder in people with intellectual disabilities.

**Search methods:** 
In February 2009, MEDLINE, PsycINFO, EMBASE, AMED, ISI Web of Science and WorldCat Dissertations were searched using an extensive list of synonyms for ADHD and ID. CENTRAL, CCDPLP, Current Controlled Trials meta-register (mRCT), CenterWatch, NHS National Research Register, clinicaltrials.gov were searched, pharmaceutical companies and experts in the field were contacted. Reference lists of review articles were examined and citation searches were performed in ISI Web of Knowledge.

**Selection criteria:** 
All randomised controlled trials (RCTs), both published and unpublished, in any language, in which children or adults with ADHD and ID were treated with risperidone.

**Data collection and analysis:** 
Data collection and analyses were planned but not performed due to a lack of suitable studies.

**Main results:** 
Eleven studies were considered but none were suitable for inclusion.

**Authors&#039; conclusions:** 
There is no evidence from RCTs that risperidone is effective for the treatment of ADHD in people with ID. Prescribing in this population can only be based on open-label studies or extrapolation from research in people with autism and disruptive behaviour disorders; however these studies have not investigated people with ID separately so there are reservations regarding the applicability of these findings. Research into effectiveness and tolerability is urgently needed.
AN  - CD007011
AU  - Thomson,
AU  - A.
AU  - Maltezos,
AU  - S.
AU  - Paliokosta,
AU  - E.
AU  - Xenitidis,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007011.pub2
KW  - Attention Deficit Disorder with Hyperactivity [drug therapy] [psychology]
KW  - Mentally Disabled Persons [psychology]
KW  - Psychotropic Drugs [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Risperidone [therapeutic use]
KW  - Adult[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2009
T2  - Cochrane Database of Systematic Reviews
TI  - Risperidone for attention-deficit hyperactivity disorder in people with intellectual disabilities
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007011.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007011.pub2/asset/CD007011.pdf?v=1&amp;t=iw7l0xe0&amp;s=b6bb6c8911b1ab2ba6172cb123c5c4a87f396ccb
ER  -
TY  - JOUR
AB  - **Background: **
Most school health education programs focus on a single behavioral domain. Integrative programs that address multiple behaviors may be more efficient, but only if the elements of change are similar for these behaviors. The objective of this study was to examine which effective elements of school health education are similar across three particular behavioral domains. 

**Methods: **
A systematic review of reviews of the effectiveness of school-based health promotion programs was conducted for the domains of substance abuse, sexual behavior, and nutrition. The literature search spanned the time period between 1995 and October 2006 and included three databases, websites of review centers and backward search. Fifty-five reviews and meta-analyses met predetermined relevance and publication criteria and were included. Data was extracted by one reviewer and checked by a second reviewer. A standardized data extraction form was used, with detailed attention to effective elements pertaining to program goals, development, content, methods, facilitator, components and intensity. Two assessors rated the quality of reviews as strong, moderate or weak. We included only strong and moderate reviews in two types of analysis: one based on interpretation of conflicting results, the other on a specific vote-counting rule. 

**Results: **
Thirty six reviews were rated strong, 6 moderate, and 13 weak. A multitude of effective elements was identified in the included reviews and many elements were similar for two or more domains. In both types of analysis, five elements with evidence from strong reviews were found to be similar for all three domains: use of theory; addressing social influences, especially social norms; addressing cognitive-behavioral skills; training of facilitators; and multiple components. Two additional elements had positive results in all domains with the rule-based method of analysis, but had inconclusive results in at least one domain with the interpretion-based method of analysis: parent involvement and a larger number of sessions. 

**Conclusion: **
Five effective elements of school health promotion were found to be similar across the three behavioral domains examined (substance abuse, sexual behavior, nutrition). An integrative program that addresses the three domains seems feasible. The five elements are primary candidates to include in programs targeting these behaviors.
AD  - [Peters, Louk W. H.; Ten Dam, Geert T. M.] Univ Amsterdam, Grad Sch Teaching &amp; Learning, Amsterdam, Netherlands. [Peters, Louk W. H.; Paulussen, Theo G. W. M.] TNO Netherlands Org Appl Sci Res Qual Life, Dept Prevent &amp; Hlth Care, Leiden, Netherlands. [Kok, Gerjo] Maastricht Univ, Fac Psychol, Maastricht, Netherlands. [Buijs, Goof J.] Netherlands Inst Hlth Promot NIGZ, Woerden, Netherlands. Peters, LWH (reprint author), Univ Amsterdam, Grad Sch Teaching &amp; Learning, Amsterdam, Netherlands. louk.peters@tno.nl; G.Kok@psychology.unimaas.nl; g.t.m.tendam@uva.nl; gbuijs@nigz.nl; theo.paulussen@tno.nl
AN  - WOS:000268141100001
AU  - Peters,
AU  - L.
AU  - W.
AU  - H.
AU  - Kok,
AU  - G.
AU  - Ten
AU  - Dam,
AU  - G.
AU  - T.
AU  - M.
AU  - Buijs,
AU  - G.
AU  - J.
AU  - Paulussen,
AU  - T.
AU  - G.
AU  - W.
AU  - M.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/1471-2458-9-182
J2  - BMC Public Health
KW  - RISK REDUCTION INTERVENTIONS RANDOMIZED CONTROLLED-TRIALS SMOKING PREVENTION PROGRAMS YOUNG-PEOPLE DRUG-ABUSE SEXUAL RISK ADOLESCENT PREGNANCY EDUCATION-PROGRAMS PHYSICAL-ACTIVITY SUBSTANCE-ABUSE Public, Environmental &amp; Occupational Health
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 472OJ Times Cited: 24 Cited Reference Count: 87 Peters, Louk W. H. Kok, Gerjo Ten Dam, Geert T. M. Buijs, Goof J. Paulussen, Theo G. W. M. Kok, Gerjo/F-4445-2012 ZonMw Netherlands Organisation for Health Research and Development [4005.0006] We thank Jimmie Leppink for his contribution to the quality rating and Lidy-Marie Ouwehand for her help with the literature searches. We also thank the referees for their helpful comments. This study was funded by ZonMw Netherlands Organisation for Health Research and Development (project no. 4005.0006). 25 BIOMED CENTRAL LTD LONDON BMC PUBLIC HEALTH
PY  - 2009
SP  - 14
T2  - Bmc Public Health
TI  - Effective elements of school health promotion across behavioral domains: a systematic review of reviews
UR  - &lt;Go to ISI&gt;://WOS:000268141100001http://www.biomedcentral.com/content/pdf/1471-2458-9-182.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - **Background:** 
Neuroleptic drugs with potent D-2 receptor blocking properties have been the traditional treatment for tics caused by Tourette Syndrome. Pimozide is the most studied of these. Use of these medications is declining because of concerns about side effects, and new atypical neuroleptics are now available. The true benefit and risks associated with pimozide compared to other drugs is not known.

**Objectives:** 
To evaluate the efficacy and harms of pimozide in comparison to placebo or other medications in the treatment of tics in Tourette Syndrome.

**Search methods:** 
We cross-referenced pimozide and its proprietary names with Tourette Syndrome and its derivations, as MeSH headings and as text words, and searched the Cochrane Movement Disorders Group Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2007, Issue 4), MEDLINE (1950-April 2007), and EMBASE (1980-April 2007). Reference lists of relevant articles were reviewed for additional trials.

**Selection criteria:**
All randomized, controlled, double blind studies comparing pimozide to placebo or other medications for the treatment of tics in Tourette Syndrome were considered for inclusion in this review. Both parallel group and crossover studies of children or adults, at any dose and for any duration, were included.

**Data collection and analysis:** 
Data was abstracted independently by two authors onto standardized forms and disagreements were resolved by discussion.

**Main results:** 
Six randomized controlled trials were included (total 162 participants, age range 7 to 53 years).&nbsp; Pimozide was compared with: placebo and haloperidol (two trials), placebo (one trial), haloperidol (one trial), and risperidone (two trials). Methodological quality was rated ?fair? for all studies. Studies used different outcome measurement scales for assessing tic severity and adverse effects. Significant clinical heterogeneity made meta-analysis inappropriate. Pimozide was superior to placebo in three studies, though it caused more side effects than placebo in one of these. Pimozide was inferior to haloperidol in one of three studies (the other two showed no significant difference between the drugs), which also showed significantly fewer side effects associated with pimozide. No significant differences between pimozide and risperidone were detected.

**Authors&#039; conclusions:** 
Pimozide is an effective treatment for tics in Tourette Syndrome, though the number of trials comparing its effect to placebo and other drugs is limited. Trials of longer duration (minimum six months) are needed to investigate the longer-term effects of pimozide compared to atypical neuroleptics.&nbsp; Future trials should use the Yale Global Tic Severity Scale to assess the main outcome measure, and quantify adverse events with the Extrapyramidal Symptoms Rating Scale.
AN  - CD006996
AU  - Pringsheim,
AU  - T.
AU  - Marras,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD006996.pub2.
KW  - Anti-Dyskinesia Agents [adverse effects] [therapeutic use]
KW  - Haloperidol [adverse effects] [therapeutic use]
KW  - Pimozide [adverse effects] [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Risperidone [adverse effects] [therapeutic use]
KW  - Tics [drug therapy]
KW  - Tourette Syndrome [drug therapy]
KW  - Humans[checkword]
KW  - Movement
PY  - 2009
T2  - Cochrane Database of Systematic Reviews
TI  - Pimozide for tics in Tourette&#039;s syndrome
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006996.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006996.pub2/asset/CD006996.pdf?v=1&amp;t=iw7kol0o&amp;s=e90380a9fae54d7b7b52d85c4b2c8cbd1c1be386
ER  -
TY  - JOUR
AB  - Medications used to treat attention-deficit/hyperactivity disorder (ADHD) have been well researched, but comparisons among agents are hindered by the absence of head-to-head clinical trials. 

By using meta-analysis, we sought to compare the efficacy of these medications for the symptoms of ADHD. We analyzed published literature on the pharmacotherapy of ADHD to describe the variability of drug-placebo effect sizes and conducted a literature search to identify double-blind, placebo-controlled studies of youths with ADHD that were published after 1979. 

Meta-analysis regression was used to assess the influence of the medication type on drug effects. We also assessed for publication bias.Thirty-two trials met our criteria and were included in this meta-analysis. These trials involved 16 drugs using 20 different outcome measures of ADHD behaviors. 

The effect sizes for immediate-release stimulants and long-acting stimulants were similar and were greater than the effect sizes for non-stimulants. There was no evidence of publication bias.Although nearly all of the ADHD medications had significant effects, we found substantial variability. 

When translated into the costs of treating large numbers of patients, these effect sizes have implications for formulary medication choices.
AN  - 20140141
AU  - Faraone,
AU  - S.
AU  - V.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810184/pdf/ptj34_12p678.pdf
DP  - Ovid Technologies
J2  - P T
LA  - English
N1  - Faraone, Stephen V
PY  - 2009
SP  - 678-94
T2  - P &amp; T
TI  - Using Meta-analysis to Compare the Efficacy of Medications for Attention-Deficit/Hyperactivity Disorder in Youths
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem&amp;AN=20140141 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:20140141&amp;id=doi:&amp;issn=1052-1372&amp;isbn=&amp;volume=34&amp;issue=12&amp;spage=678&amp;pages=678-94&amp;date=2009&amp;title=P+%26+T&amp;atitle=Using+Meta-analysis+to+Compare+the+Efficacy+of+Medications+for+Attention-Deficit%2FHyperactivity+Disorder+in+Youths.&amp;aulast=Faraone&amp;pid=%3Cauthor%3EFaraone+SV%3C%2Fauthor%3E%3CAN%3E20140141%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 34
ER  -
TY  - JOUR
AB  - **Background:**
Long-term drug treatment of schizophrenia with typical antipsychotic drugs has limitations: 25 to 33% of sufferers have illnesses that are treatment resistant. Clozapine is an antipsychotic drug, which is claimed to have superior efficacy and to cause fewer motor adverse effects than typical drugs for people with treatment-resistant illnesses. Clozapine carries a significant risk of serious blood disorders, which necessitates mandatory weekly blood monitoring at least during the first months of treatment.

**Objectives:** 
To evaluate the effects of clozapine compared with typical antipsychotic drugs in people with schizophrenia.Search methods: For the current update of this review (November 2008) we searched the Cochrane Schizophrenia Group Trials Register.

**Selection criteria:** 
All relevant randomised controlled trials (RCTs).

**Data collection and analysis:** 
We extracted data independently. For dichotomous data we calculated relative risks (RR) and their 95% confidence intervals (CI) on an intention-to-treat basis, based on a fixed-effect model. We calculated numbers needed to treat/harm (NNT/NNH) where appropriate. For continuous data, we calculated weighted mean differences (WMD) again based on a fixed-effect model.

**Main results:** 
We have included 52 trials (4746 participants) in this review. Forty-four of the included studies are less than 13 weeks in duration, and, overall, trials were at a significant risk of bias. We found no significant difference in the effects of clozapine and typical neuroleptic drugs for broad outcomes such as mortality, ability to work or suitability for discharge at the end of the study. Clinical improvements were seen more frequently in those taking clozapine (n=1119, 14 RCTs, RR 0.72 CI 0.7 to 0.8, NNT 6 CI 5 to 8). Also, participants given clozapine had fewer relapses than those on typical antipsychotic drugs (n=1303, RR 0.62 CI 0.5 to 0.8, NNT 21 CI 15 to 49). BPRS scores showed a greater reduction of symptoms in clozapine-treated participants, (n=1205, 17 RCTs, WMD -3.79 CI -4.9 to -2.7), although the data were heterogeneous ( I2=69%). Short-term data from the SANS negative symptom scores favoured clozapine (n=196, 6 RCTs, WMD -7.21 CI -8.9 to -5.6). We found clozapine to be more acceptable in long-term treatment than conventional antipsychotic drugs (n=982, 6 RCTs, RR 0.60 CI 0.5 to 0.7, NNT 15 CI 12 to 20). Blood problems occurred more frequently in participants receiving clozapine (3.2%) compared with those given typical antipsychotic drugs (0%) (n=1031, 13 RCTs, RR 7.09 CI 2.0 to 25.6). Clozapine participants experienced more drowsiness, hypersalivation or temperature increase, than those given conventional neuroleptics. However, those receiving clozapine experienced fewer motor adverse effects (n=1495, 19 RCTs, RR 0.57 CI 0.5 to 0.7, NNT 5 CI 4 to 6).The clinical effects of clozapine were more pronounced in participants resistant to typical neuroleptics in terms of clinical improvement (n=370, 4 RCTs, RR 0.71 CI 0.6 to 0.8, NNT 4 CI 3 to 6) and symptom reduction. Thirty-four per cent of treatment-resistant participants had a clinical improvement with clozapine treatment.

**Authors&#039; conclusions:** 
Clozapine may be more effective in reducing symptoms of schizophrenia, producing clinically meaningful improvements and postponing relapse, than typical antipsychotic drugs - but data are weak and prone to bias. Participants were more satisfied with clozapine treatment than with typical neuroleptic treatment. The clinical effect of clozapine, however, is, at least in the short-term, not reflected in measures of global functioning such as ability to leave the hospital and maintain an occupation. The short-term benefits of clozapine have to be weighed against the risk of adverse effects. Within the context of trials, the potentially dangerous white blood cell decline seems to be more frequent in children and adolescents and in the elderly than in young adults or people of middle age.The existing trials have largely neglected to assess the views of participants and their families on clozapine ore community-based long-term randomised trials are needed to evaluate the efficacy of clozapine on global and social functioning as trials in special groups such as people with learning disabilities.
AN  - CD000059
AU  - Essali,
AU  - A.
AU  - Al-Haj
AU  - Haasan,
AU  - N.
AU  - Li,
AU  - C.
AU  - Rathbone,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd000059.pub2
KW  - Age Factors
KW  - Antipsychotic Agents [adverse effects] [therapeutic use]
KW  - Clozapine [adverse effects] [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Schizophrenia [drug therapy]
KW  - Humans[checkword]
KW  - Schiz
PY  - 2009
T2  - Cochrane Database of Systematic Reviews
TI  - Clozapine versus typical neuroleptic medication for schizophrenia
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000059.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD000059.pub2/asset/CD000059.pdf?v=1&amp;t=iw7j30tm&amp;s=a38798abc325dbbd031aca298cbcb189bddeb724
ER  -
TY  - JOUR
AB  - **AIM: **
A wide range of psychosocial interventions for the treatment of individuals with autism-spectrum disorders (ASDs) have been evaluated in systematic reviews. We conducted an umbrella review of systematic reviews of the effectiveness of psychosocial interventions for ASD. 

**METHOD: **
Comprehensive searches were conducted in 25 bibliographic databases, relevant journals and reference lists up to May 2007. Studies included were systematic reviews on any psychosocial intervention for individuals with ASDs. Two reviewers independently assessed study relevance and quality. 

**RESULTS: **
Thirty systematic reviews were included. The majority of reviews evaluated interventions based on behavioural theory (n=9) or communication-focused (n=7) therapies. Positive intervention outcomes were reported in the majority of the reviews. Methodological quality of the reviews was generally poor. 

**INTERPRETATION: **
The reviews reported positive outcomes for many of the interventions, suggesting that some form of treatment is favourable over no treatment. However, there is little evidence for the relative effectiveness of these treatment options. Many of the systematic reviews had methodological weaknesses that make them vulnerable to bias. There is a need for further systematic reviews that adhere to strict scientific methods and for primary studies that make direct comparisons between different treatment options.
AN  - 19191842
AU  - Seida,
AU  - J.
AU  - K.
AU  - Ospina,
AU  - M.
AU  - B.
AU  - Karkhaneh,
AU  - M.
AU  - Hartling,
AU  - L.
AU  - Smith,
AU  - V.
AU  - Clark,
AU  - B.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.1111/j.1469-8749.2008.03211.x
L1  - internal-pdf://1214455924/Seida-2009-Systematic reviews of psychosocial.pdf
PY  - 2009
SP  - 95-104
T2  - Developmental Medicine &amp; Child Neurology
TI  - Systematic reviews of psychosocial interventions for autism: an umbrella review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=19191842
UR  - https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1469-8749.2008.03211.x
VL  - 51
ER  -
TY  - JOUR
AB  - The purpose of this article is to provide a comprehensive review of school-based suicide prevention programs from a public health perspective. A literature review of empirical studies examining school-based suicide prevention programs was conducted. Studies were required to contain information pertaining to the implementation and outcomes of a school-based program designed to address suicidal behaviors among children and youth. A total of 13 studies was identified. 

Most of the studies (77%) were classified as universal suicide prevention programs (n = 10), with the remaining studies classified as selected suicide prevention programs (n = 3). Studies were coded based on key methodological features of the Task Force on Evidence-Based Interventions in School Psychology Procedural and Coding Manual (Kratochwill &amp; Stoiber, 2002). The highest methodology ratings were obtained by two universal suicide prevention programs (Klingman &amp; Hochdorf, 1993; LaFromboise &amp; Howard-Pitney, 1995) and one selected prevention program (Randell, Eggert, &amp; Pike, 2001), although the selected suicide prevention programs demonstrated proportionally more key methodological features than the universal suicide prevention programs. However, only 2 of the 13 studies reviewed demonstrated strong evidence for statistically significant effects on primary outcome measures. 

Very few studies provided promising evidence of educational/clinical significance (7.6%), identifiable components linked to statistically significant primary outcomes (23.1%), and program implementation integrity (23.1%). Furthermore, no studies provided evidence supporting the replication of program effects. The implications of these results for practice are discussed as well as needs for future research. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Miller, David N.: dmiller@uamail.albany.edu Miller, David N.: University at Albany, SUNY, 1400 Washington Avenue, ED 215, Albany, NY, US, 12222, dmiller@uamail.albany.edu Miller, David N.: University at Albany, State University of New York, Albany, NY, US Eckert, Tanya L.: Syracuse University, Syracuse, NY, US Mazza, James J.: University of Washington, Seattle, WA, US
AN  - 2009-09788-002
AU  - Miller,
AU  - D.
AU  - N.
AU  - Eckert,
AU  - T.
AU  - L.
AU  - Mazza,
AU  - J.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Har ikke DOI: https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0027564/
DP  - Ovid Technologies
KW  - suicide prevention programs, schools, public health, school-based suicide prevention programs *Mental Health Programs *School Based Intervention *Suicide Prevention Public Health Schools Educational/Vocational Counseling &amp; Student Services [3580] Human
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2009
SP  - 168-188
T2  - School Psychology Review
TI  - Suicide prevention programs in the schools: A review and public health perspective
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc6&amp;AN=2009-09788-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=0279-6015&amp;isbn=&amp;volume=38&amp;issue=2&amp;spage=168&amp;pages=168-188&amp;date=2009&amp;title=School+Psychology+Review&amp;atitle=Suicide+prevention+programs+in+the+schools%3A+A+review+and+public+health+perspective.&amp;aulast=Miller&amp;pid=%3Cauthor%3EMiller%2C+David+N%3C%2Fauthor%3E%3CAN%3E2009-09788-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 38
ER  -
TY  - JOUR
AB  - The Drug Abuse Resistance Education (D.A.R.E.) program is a widespread but controversial school-based drug prevention program in the United States as well as in many other countries. 

The present multivariate meta-analysis reviewed 20 studies that assessed the effectiveness of the D.A.R.E. program in the United States. The results showed that the effects of the D.A.R.E. program on drug use did not vary across the studies with a less than small overall effect while the effects on psychosocial behavior varied with still a less than small overall effect. 

In addition, the characteristics of the studies significantly explained the variation of the heterogeneous effects on psychosocial behavior, which provides empirical evidence for improving the school-based drug prevention program.
AN  - 354251156
AU  - Pan,
AU  - W.
AU  - Bai,
AU  - H.
DB  - Rekoding IN SUM_lme.enl
DO  - /10.3390/ijerph6010267
L1  - internal-pdf://3752275937/Pan-2009-A multivariate approach to a meta-ana.pdf
PY  - 2009
SP  - 267-277
T2  - International Journal of Environmental Research and Public Health
TI  - A multivariate approach to a meta-analytic review of the effectiveness of the D.A.R.E. program
UR  - http://www.mdpi.com/1660-4601/6/1/267/pdf
UR  - https://mdpi-res.com/d_attachment/ijerph/ijerph-06-00267/article_deploy/ijerph-06-00267.pdf
VL  - 6(1)
ER  -
TY  - JOUR
AB  - **Objective:** 
Siblings of pediatric cancer patients have been shown to be at risk for developing emotional, behavioral, and social problems. There is a need for psychological interventions in this population. Several researchers have previously documented and evaluated their interventions with siblings. This paper aimed at reviewing the existing reports of evaluated psychological interventions with siblings of pediatric cancer patients and at outlining future directions. 

**Methods:** 
Research was conducted on several online bibliographic databases. Articles were selected on the basis of predefined criteria. If possible, effect sizes (ES) were calculated. 

**Results:** 
Fourteen studies representing 11 different sibling interventions met criteria for inclusion. One individual intervention, three camps, and seven groups were found. Objectives of interventions concentrated mainly on enhancing siblings&#039; coping and improving their medical knowledge. In terms of outcome measures, most of the studies focused on psychological adjustment variables. Findings showed significant improvements in siblings&#039; depression symptomatology, medical knowledge, and health-related quality of life. Findings were inconsistent with regard to anxiety, behavioral problems, social adjustment, self-esteem, and posttraumatic stress symptoms. Depending on the outcome variables, small to large ES were found. Satisfaction with the intervention was high in both siblings and parents. 

**Conclusion:** There is tentative evidence that psychological interventions with siblings of childhood cancer patients can effectively reduce psychological maladjustment and improve medical knowledge about cancer. However, the number of studies is small, and several methodological shortcomings have to be noted. In future, more randomized controlled trials need to be conducted in larger samples to extend the evidence base. 

Copyright (C) 2009 John Wiley &amp; Sons, Ltd.
AD  - [Prchal, Alice; Landolt, Markus A.] Univ Childrens Hosp Zurich, Dept Psychosomat &amp; Psychiat, CH-8032 Zurich, Switzerland. Prchal, A (reprint author), Univ Childrens Hosp Zurich, Dept Psychosomat &amp; Psychiat, Steinwiesstr 75, CH-8032 Zurich, Switzerland. alice.prchal@kispi.uzh.ch
AN  - WOS:000272734500001
AU  - Prchal,
AU  - A.
AU  - Landolt,
AU  - M.
AU  - A.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/pon.1565
J2  - Psycho-Oncol.
KW  - pediatric cancer oncology siblings psychological intervention review QUALITY-OF-LIFE CHILDHOOD-CANCER POSTTRAUMATIC STRESS CHRONIC ILLNESS ADOLESCENT SURVIVORS ONCOLOGY PATIENTS CHILDREN ADAPTATION ADJUSTMENT FAMILIES Oncology Psychology Psychology, Mul
L1  - internal-pdf://3047356991/Prchal-2009-Psychological interventions with s.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 532GN Times Cited: 9 Cited Reference Count: 75 Prchal, Alice Landolt, Markus A. 9 JOHN WILEY &amp; SONS LTD CHICHESTER PSYCHO-ONCOLOGY
PY  - 2009
SP  - 1241-1251
T2  - Psycho-Oncology
TI  - Psychological interventions with siblings of pediatric cancer patients: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000272734500001http://onlinelibrary.wiley.com/store/10.1002/pon.1565/asset/1565_ftp.pdf?v=1&amp;t=ib3ke46l&amp;s=5bb95ba989278fa729d6f2467a79af438c4ce413
UR  - http://onlinelibrary.wiley.com/store/10.1002/pon.1565/asset/1565_ftp.pdf?v=1&amp;t=j8yewy8h&amp;s=4f828010ce32557891f681417ebf08f9f6f2a303
VL  - 18
ER  -
TY  - JOUR
AB  - This review sought to determine the evidence base of augmentative and alternative communication (AAC) use with infants and toddlers with disabilities. 

The review identified 12 studies, involving 190 participants aged 36 months or younger. The majority of the studies investigated unaided AAC methods (e. g., gestures or sign language), with 42% of the studies also including aided AAC methods. 

Although all studies reported improvement in child communication following AAC intervention, in-depth analyses of study methodology indicated that only 7 out of 12 provided conclusive evidence. Implications for early intervention AAC practice and suggestions for future research are proposed.
AD  - [Branson, Diane; Demchak, Maryann] Univ Nevada, Reno, NV USA. Branson, D (reprint author), Univ Nevada, Reno, NV USA. dmbranson@aol.com
AN  - WOS:000272968300006
AU  - Branson,
AU  - D.
AU  - Demchak,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3109/07434610903384529
J2  - Augment. Altern. Commun.
KW  - Augmentative and alternative communication Developmental disabilities Intervention Research synthesis Effectiveness PRELINGUISTIC COMMUNICATION AAC TECHNOLOGIES CHILDREN INTERVENTION AUTISM ACQUISITION Audiology &amp; Speech-Language Pathology Rehabilitatio
L1  - internal-pdf://3854710459/Branson-2009-The Use of Augmentative and Alter.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 535KY Times Cited: 12 Cited Reference Count: 38 Branson, Diane Demchak, Maryann 12 TAYLOR &amp; FRANCIS LTD ABINGDON AUGMENT ALTERN COMM
PY  - 2009
SP  - 274-286
T2  - Augmentative and Alternative Communication
TI  - The Use of Augmentative and Alternative Communication Methods with Infants and Toddlers with Disabilities: A Research Review
UR  - &lt;Go to ISI&gt;://WOS:000272968300006http://informahealthcare.com/doi/pdfplus/10.3109/07434610903384529
UR  - http://www.tandfonline.com/doi/pdf/10.3109/07434610903384529?needAccess=true
VL  - 25
ER  -
TY  - JOUR
AB  - **Objective **
To synthesize recent evidence from systematic and comprehensive reviews on the effectiveness of universal and selective child maltreatment prevention interventions, evaluate the methodological quality of the reviews and outcome evaluation studies they are based on, and map the geographical distribution of the evidence. 

**Methods **
A systematic review of reviews was conducted. The quality of the systematic reviews was evaluated with a tool for the assessment of multiple systematic reviews (AMSTAR), and the quality of the outcome evaluations was assessed using indicators of internal validity and of the construct validity of outcome measures. 

**Findings **
The review focused on seven main types of interventions: home visiting, parent education, child sex abuse prevention, abusive head trauma prevention, multi-component interventions, media-based interventions, and support and mutual aid groups. Four of the seven - home-visiting, parent education, abusive head trauma prevention and multi-component interventions - show promise in preventing actual child maltreatment. Three of them - home visiting, parent education and child sexual abuse prevention - appear effective in reducing risk factors for child maltreatment, although these conclusions are tentative due to the methodological shortcomings of the reviews and outcome evaluation studies they draw on. An analysis of the geographical distribution of the evidence shows that outcome evaluations of child maltreatment prevention interventions are exceedingly rare in low- and middle-income countries and make up only 0.6% of the total evidence base. 

**Conclusion **
Evidence for the effectiveness of four of the seven main types of interventions for preventing child maltreatment is promising, although it is weakened by methodological problems and paucity of outcome evaluations from low- and middle-income countries.
AD  - [Mikton, Christopher; Butchart, Alexander] World Hlth Org, Dept Violence &amp; Injury Prevent &amp; Disabil, CH-1211 Geneva 27, Switzerland. Mikton, C (reprint author), World Hlth Org, Dept Violence &amp; Injury Prevent &amp; Disabil, 20 Ave Appia, CH-1211 Geneva 27, Switzerland. miktonc@who.int
AN  - WOS:000265956200011
AU  - Mikton,
AU  - C.
AU  - Butchart,
AU  - A.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1590/S0042-96862009000500012
J2  - Bull. World Health Organ.
KW  - SEXUAL-ABUSE PREVENTION HOME VISITATION YOUNG-CHILDREN PROGRAMS METAANALYSIS STANDARDS FAMILIES OUTCOMES STRATEGY NEGLECT Public, Environmental &amp; Occupational Health
L1  - internal-pdf://1239038235/Mikton-2009-Child maltreatment prevention_ a s.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 444BX Times Cited: 64 Cited Reference Count: 48 Mikton, Christopher Butchart, Alexander 68 WORLD HEALTH ORGANIZATION GENEVA 27 B WORLD HEALTH ORGAN
PY  - 2009
SP  - 353-361
T2  - Bulletin of the World Health Organization
TI  - Child maltreatment prevention: a systematic review of reviews
UR  - &lt;Go to ISI&gt;://WOS:000265956200011http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678770/pdf/08-057075.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678770/pdf/08-057075.pdf
VL  - 87
ER  -
TY  - JOUR
AB  - **Objective:** 
The authors examined characteristics and predictors of response to placebo in all available reports of short-term randomized controlled trials of antidepressants for pediatric major depressive disorder. 

**Method:**
Response, defined as a score &lt;2 on the improvement item of the Clinical Global Impression scale, and potential predictors were extracted from 12 published and unpublished randomized controlled trials of second-generation antidepressants in participants 6-18 years of age with major depression. 

**Results:**
The single best predictor of the proportion of patients taking placebo who responded to treatment was the number of study sites. Baseline severity of illness also emerged as a significant inverse predictor of placebo response, although the strength of this relationship was diminished when number of sites was controlled for. After one large fluoxetine trial was excluded, younger participants showed a higher placebo response rate than older adolescents. Higher placebo response rates in more recent studies were explained by an increasing trend toward large multisite trials and by publication delays and failures to publish some negative trials. 

**Conclusions:** 
The recent shift toward large multisite trials of antidepressant medications for pediatric major depression may be contributing to an increasing incidence of response to placebo. Pharmacotherapy studies of pediatric depression that carefully recruit patients with at least moderately severe depression may be more informative and efficient than many trials conducted to date. Such studies should have sufficient power to determine whether age moderates medication and placebo response. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Bridge, Jeffrey A.: jeff.bridge@nationwidechildrens.org Bridge, Jeffrey A.: Research Institute at Nationwide Children&#039;s Hospital, Center for Innovation in Pediatric Practice, 700 Children&#039;s Dr., Columbus, OH, US, 43205, jeff.bridge@nationwidechildrens.org
AN  - 2009-00353-011
AU  - Bridge,
AU  - J.
AU  - A.
AU  - Birmaher,
AU  - B.
AU  - Iyengar,
AU  - S.
AU  - Barbe,
AU  - R.
AU  - Brent,
AU  - D.
AU  - A.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1176/appi.ajp.2008.08020247
DP  - Ovid Technologies
KW  - placebo response, randomized controlled trials, antidepressants, pediatric major depressive disorder, pharmacotherapy, pediatrics *Antidepressant Drugs *Clinical Trials *Major Depression *Placebo *Responses Drug Therapy Pediatrics Clinical Psychopharmac
LA  - English
M3  - Meta Analysis
PY  - 2009
SP  - 42-49
T2  - The American Journal of Psychiatry
TI  - Placebo response in randomized controlled trials of antidepressants for pediatric major depressive disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc6&amp;AN=2009-00353-011 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1176%2Fappi.ajp.2008.08020247&amp;issn=0002-953X&amp;isbn=&amp;volume=166&amp;issue=1&amp;spage=42&amp;pages=42-49&amp;date=2009&amp;title=The+American+Journal+of+Psychiatry&amp;atitle=Placebo+response+in+randomized+controlled+trials+of+antidepressants+for+pediatric+major+depressive+disorder.&amp;aulast=Bridge&amp;pid=%3Cauthor%3EBridge%2C+Jeffrey+A%3C%2Fauthor%3E%3CAN%3E2009-00353-011%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://media.proquest.com/media/pq/classic/doc/1621890951/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Bridge%2C+Jeffrey+A%2C+PhD%3BBirmaher%2C+Boris%2C+MD%3BIyengar%2C+Satish%2C+PhD%3BBarbe%2C+R%C3%A9my+P%2C+MD%3BBrent%2C+David+A%2C+MD&amp;cit%3Atitle=Placebo+Response+in+Randomized+Controlled+Trials+of+Antidepressants+...&amp;cit%3Apub=The+American+Journal+of+Psychiatry&amp;cit%3Avol=166&amp;cit%3Aiss=1&amp;cit%3Apg=42&amp;cit%3Adate=Jan+2009&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYzMDA3NTc1NzM5MDoxODQyMjQSBTk1NTczGgpPTkVfU0VBUkNIIg8xOTMuMTU3LjEzNy4xNjUqBTQwNjYxMgkyMjA0ODE2ODM6DURvY3VtZW50SW1hZ2VCATBSBk9ubGluZVoCRlRiA1BGVGoKMjAwOS8wMS8wMXIKMjAwOS8wMS8zMXoAggEpUC0xMDAwMjczLTMxMDc1LUNVU1RPTUVSLTEwMDAwMTU3LTExMTUxMTKSAQZPbmxpbmXKAQdFbmROb3Rl0gESU2Nob2xhcmx5IEpvdXJuYWxzmgIHUHJlUGFpZKoCKE9TOkVNUy1QZGZEb2NWaWV3QmFzZS1nZXRNZWRpYVVybEZvckl0ZW3KAg9GZWF0dXJlfEFydGljbGXSAgFZ4gIBTvICAA%3D%3D&amp;_s=5%2FsGaDRe%2FtTujjwses1zhgnCG%2Fk%3D
VL  - 166
ER  -
TY  - JOUR
AB  - In this meta-analytic review, the authors summarized the effects of depression prevention programs for youth as well as investigated participant, intervention, provider, and research design features associated with larger effects. 

They identified 47 trials that evaluated 32 prevention programs, producing 60 intervention effect sizes. The average effect for depressive symptoms from pre-to-posttreatment (r = .15) and pretreatment to-follow-up (r = .11) were small, but 13 (41%) prevention programs produced significant reductions in depressive symptoms and 4 (13%) produced significant reductions in risk for future depressive disorder onset relative to control groups.

Larger effects emerged for programs targeting high-risk individuals, samples with more females, samples with older adolescents, programs with a shorter duration and with homework assignments, and programs delivered by professional interventionists. 

Intervention content (e.g., a focus on problem-solving training or reducing negative cognitions) and design features (e.g., use of random assignment and structured interviews) were unrelated to effect sizes. 

Results suggest that depression prevention efforts produce a higher yield if they incorporate factors associated with larger intervention effects (e.g., selective programs with a shorter duration that include homework).

Copyright 2009 APA
AD  - Stice,Eric. Oregon Research Institute, Eugene, Oregon 97403, USA. estice@ori.org
AN  - 19485590
AU  - Stice,
AU  - E.
AU  - Shaw,
AU  - H.
AU  - Bohon,
AU  - C.
AU  - Marti,
AU  - C.
AU  - N.
AU  - Rohde,
AU  - P.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1037/a0015168
DP  - Ovid Technologies
J2  - J Consult Clin Psychol
KW  - Adolescent Age Factors Child Culture Depressive Disorder, Major/di [Diagnosis] *Depressive Disorder, Major/pc [Prevention &amp; Control] Depressive Disorder, Major/px [Psychology] Female Humans Interview, Psychological Male Outcome and Process Assessment (H
L1  - internal-pdf://3074457458/Stice-2009-A meta-analytic review of depressio.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural
N1  - Stice, Eric Shaw, Heather Bohon, Cara Marti, C Nathan Rohde, Paul MH 67183 (United States NIMH NIH HHS) R01 MH067183 (United States NIMH NIH HHS) R01 MH067183-01A2 (United States NIMH NIH HHS) R01 MH067183-02 (United States NIMH NIH HHS) R01 MH067183-03 (United States NIMH NIH HHS) R01 MH067183-04 (United States NIMH NIH HHS) R01 MH067183-05 (United States NIMH NIH HHS)
PY  - 2009
SP  - 486-503
T2  - Journal of Consulting and Clinical Psychology
TI  - A meta-analytic review of depression prevention programs for children and adolescents: factors that predict magnitude of intervention effects
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19485590 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19485590&amp;id=doi:10.1037%2Fa0015168&amp;issn=0022-006X&amp;isbn=&amp;volume=77&amp;issue=3&amp;spage=486&amp;pages=486-503&amp;date=2009&amp;title=Journal+of+Consulting+%26+Clinical+Psychology&amp;atitle=A+meta-analytic+review+of+depression+prevention+programs+for+children+and+adolescents%3A+factors+that+predict+magnitude+of+intervention+effects.&amp;aulast=Stice&amp;pid=%3Cauthor%3EStice+E%3C%2Fauthor%3E%3CAN%3E19485590%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758769/pdf/nihms128932.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758769/pdf/nihms128932.pdf
VL  - 77
ER  -
TY  - JOUR
AB  - **Background: **
There is a growing body of literature on interventions addressing psychosocial wellbeing and mental health of children affected by violence in low- and middle-income countries. 

**Methods: **
This systematic review of PubMed, PsychINFO, and PILOTS identified 500 publications (1991-2008) on interventions. 

**Results:** 
Sixty-six publications (12 treatment outcome studies and 54 intervention descriptions, covering a range of treatment modalities) met inclusion criteria. Most interventions are evaluated positively, while some studies lack evidence for efficacy and effectiveness. 

**Conclusion: **
Scarcity of rigorous studies, diversity of interventions, and mixed results of evaluations demonstrate a need to identify evidence-based interventions. The literature presents consensus on a number of treatment-related issues, yet the application remains limited across interventions.
AD  - [Jordans, Mark J. D.; Tol, Wietse A.; Komproe, Ivan H.] Healthnet TPO, Dept Publ Hlth &amp; Res, Amsterdam, Netherlands. [Jordans, Mark J. D.; Tol, Wietse A.; de Jong, Joop V. T. M.] Vrije Univ Amsterdam, Med Ctr, Amsterdam, Netherlands. [de Jong, Joop V. T. M.] Boston Univ, Sch Med, Boston, MA 02215 USA. Jordans, MJD (reprint author), Healthnet TPO, Dept Publ Hlth &amp; Res, Amsterdam, Netherlands. mjordans@healthnettpo.org
AN  - WOS:000207854600001
AU  - Jordans,
AU  - M.
AU  - J.
AU  - D.
AU  - Tol,
AU  - W.
AU  - A.
AU  - Komproe,
AU  - I.
AU  - H.
AU  - De
AU  - Jong,
AU  - J.
AU  - V.
AU  - T.
AU  - M.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1475-3588.2008.00515.x
J2  - Child Adolesc. Ment. Health
KW  - Systematic review children low- and middle-income countries war psychosocial mental health treatment effectiveness efficacy Psychology, Clinical Pediatrics Psychiatry
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: V16FD Times Cited: 46 Cited Reference Count: 80 Jordans, Mark J. D. Tol, Wietse A. Komproe, Ivan H. de Jong, Joop V. T. M. Tol, Wietse/G-8587-2013 Tol, Wietse/0000-0003-2216-0526 PLAN Netherlands This study was conducted with a grant from PLAN Netherlands. We would like to thank Vicky Verschoor and Brandon Kohrt for their contributions to this study. 46 WILEY-BLACKWELL PUBLISHING, INC MALDEN CHILD ADOL MENT H-UK
PY  - 2009
SP  - 2-14
T2  - Child and Adolescent Mental Health
TI  - Systematic Review of Evidence and Treatment Approaches: Psychosocial and Mental Health Care for Children in War
UR  - &lt;Go to ISI&gt;://WOS:000207854600001http://onlinelibrary.wiley.com/store/10.1111/j.1475-3588.2008.00515.x/asset/j.1475-3588.2008.00515.x.pdf?v=1&amp;t=ib7ngwnf&amp;s=11e41628692f7139b93876e0d64b3d38fedcad1d
VL  - 14
ER  -
TY  - JOUR
AB  - A systematic review was conducted of school-based prevention and early intervention programs for anxiety. 
The aim of the review was to identify and describe the programs available, and to evaluate their effectiveness in reducing symptoms of anxiety. 

Twenty-seven outcome trials, describing 20 individual programs, were identified through the Cochrane Library, PsycInfo and PubMed databases. 

Results of the review indicated that most universal, selective and indicated prevention programs are effective in reducing symptoms of anxiety in children and adolescents, with effect sizes ranging from 0.11 to 1.37. 

Most programs targeted adolescents (59%), were aimed at reducing the symptoms of nonspecific anxiety (67%), and delivered cognitive behavioural therapy (CBT; 78%). 

Further quality school-based research is required that involves longer-term follow-up, the use of attention control conditions and evaluates teacher delivery. 

(C) 2009 Elsevier Ltd. All rights reserved.
AD  - [Neil, Alison L.; Christensen, Helen] Australian Natl Univ, Mental Hlth Res Ctr, Canberra, ACT 0200, Australia. Neil, AL (reprint author), Australian Natl Univ, Mental Hlth Res Ctr, Bldg 63,Eggleston Rd, Canberra, ACT 0200, Australia. Alison.Neil@anu.edu.au
AN  - WOS:000264858900002
AU  - Neil,
AU  - A.
AU  - L.
AU  - Christensen,
AU  - H.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2009.01.002
J2  - Clin. Psychol. Rev.
KW  - Anxiety School-based Prevention Early intervention RANDOMIZED CONTROLLED-TRIAL MENTAL-HEALTH-SERVICES LONG-TERM OUTCOMES ACADEMIC-PERFORMANCE DEPRESSIVE-DISORDERS FOLLOW-UP ADOLESCENTS CHILDREN UNIVERSAL CHILDHOOD Psychology, Clinical
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 428OS Times Cited: 69 Cited Reference Count: 63 Neil, Alison L. Christensen, Helen Calear, Alison/D-4191-2009; Christensen, Helen/F-5053-2012 Calear, Alison/0000-0002-7028-725X; 69 PERGAMON-ELSEVIER SCIENCE LTD OXFORD CLIN PSYCHOL REV
PY  - 2009
SP  - 208-215
T2  - Clinical Psychology Review
TI  - Efficacy and effectiveness of school-based prevention and early intervention programs for anxiety
UR  - &lt;Go to ISI&gt;://WOS:000264858900002http://ac.els-cdn.com/S0272735809000038/1-s2.0-S0272735809000038-main.pdf?_tid=5b53e4fe-1972-11e5-8074-00000aab0f27&amp;acdnat=1435041645_07d232d5c854aaab01f9e71ed5ac0468
VL  - 29
ER  -
TY  - JOUR
AB  - **Objective.**
-The aim of this study was to evaluate the evidence for clinical applications of yoga among the pediatric population.
 
**Methods.**-We conducted an electronic literature search including CINAHL, Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, Medline. PsycINFO, and manual search of retrieved articles from inception of each database until December 2008. Randomized controlled trials (RCTs) and non-randomized controlled trials (NRCTs) were selected that included yoga or yoga-based interventions for individuals aged 0 to 21 years. Data were extracted and articles critically reviewed using a modified Jadad score and descriptive methodological criteria, with summarization in tables. 

**Results.**
-Thirty-four controlled studies published from 1979 to 2008 were identified, with 19 RCTS and 15 NRCTs. Many studies were of low methodological quality. Clinical areas for which yoga has been studied include physical fitness, cardiorespiratory effects, motor skills/strength, mental health and psychological disorders, behavior and development, irritable bowel syndrome, and birth outcomes following prenatal yoga. No adverse events were reported in trials reviewed. Although a large majority of studies were positive, methodological limitations such as randomization methods, withdrawal/dropouts, and details of yoga intervention preclude conclusive evidence. 

**Conclusions.**
-There are limited data on the clinical applications of yoga among the pediatric population. Most published controlled trials were suggestive of benefit, but results are preliminary based on low quantity and quality of trials. 
Further research of yoga for children by using a higher standard of methodology and reporting is warranted.
AD  - [Birdee, Gurjeet S.; Yeh, Gloria Y.; Wayne, Peter M.; Phillips, Russell S.; Davis, Roger B.] Harvard Univ, Sch Med, Div Res &amp; Educ Complementary &amp; Integrat Med Thera, Osher Res Ctr, Boston, MA 02215 USA. [Birdee, Gurjeet S.; Yeh, Gloria Y.; Phillips, Russell S.; Davis, Roger B.] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Gen Med &amp; Primary Care,Dept Med, Boston, MA 02215 USA. [Gardiner, Paula] Boston Univ, Sch Med, Boston Med Ctr, Dept Family Med, Boston, MA 02118 USA. Birdee, GS (reprint author), Harvard Univ, Sch Med, Div Res &amp; Educ Complementary &amp; Integrat Med Thera, Osher Res Ctr, 401 Pk Dr,Suite 22-A W, Boston, MA 02215 USA. gurjeet_birdee@hms.harvard.edu
AN  - WOS:000275913200004
AU  - Birdee,
AU  - G.
AU  - S.
AU  - Yeh,
AU  - G.
AU  - Y.
AU  - Wayne,
AU  - P.
AU  - M.
AU  - Phillips,
AU  - R.
AU  - S.
AU  - Davis.
AU  - R.
AU  - B.
AU  - Gardiner,
AU  - P.
DA  - Jul-Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.acap.2009.04.002
J2  - Acad. Pediatr.
KW  - behavioral medicine children complementary and alternative medicine pediatric yoga LOW-BACK-PAIN HATHA YOGA INTEGRATED APPROACH BRONCHIAL-ASTHMA CONTROLLED-TRIAL IYENGAR YOGA CHILDREN INTERVENTIONS EXERCISES QUALITY Pediatrics
L1  - internal-pdf://0297935277/Birdee-2009-Clinical Applications of Yoga for.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 573KV Times Cited: 24 Cited Reference Count: 73 Birdee, Gurjeet S. Yeh, Gloria Y. Wayne, Peter M. Phillips, Russell S. Davis, Roger B. Gardiner, Paula 25 ELSEVIER SCIENCE INC NEW YORK ACAD PEDIATR
PY  - 2009
SP  - 212-220
T2  - Academic Pediatrics
TI  - Clinical Applications of Yoga for the Pediatric Population: A Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000275913200004http://ac.els-cdn.com/S1876285909001028/1-s2.0-S1876285909001028-main.pdf?_tid=b9111d3a-167c-11e5-b50b-00000aab0f6b&amp;acdnat=1434716244_ef394c436b277d29da13c5ccba6941bb
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844096/pdf/nihms110852.pdf
VL  - 9
ER  -
TY  - JOUR
AB  - Recent reviews highlight limitations in the evidence base for early interventions for children with autism. 

We conducted a systematic review of controlled studies of early intensive behavioral interventions (EIBI) for young children with autism. 

Eleven studies met inclusion criteria (including two randomized controlled trials). At group level, EIBI resulted in improved outcomes (primarily measured by IQ) compared to comparison groups. 

At an individual level, however, there was considerable variability in outcome, with some evidence that initial IQ (but not age) was related to progress. 

This review provides evidence for the effectiveness of EIBI for some, but not all, preschool children with autism.
AD  - [Howlin, Patricia] Kings Coll London, Dept Psychol, Inst Psychiat, London SE5 8AF, England. [Charman, Tony] UCL, Inst Child Hlth, London WC1E 6BT, England. Howlin, P (reprint author), Kings Coll London, Dept Psychol, Inst Psychiat, Henry Wellcome Bldg,PO 77,De Crespigny Pk, London SE5 8AF, England. patricia.howlin@iop.kcl.ac.uk
AN  - WOS:000265422000004
AU  - Howlin,
AU  - P.
AU  - Magiati,
AU  - I.
AU  - Charman,
AU  - T.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1352/2009.114:23;nd41
J2  - AJIDD-Am. J. Intellect. Dev. Disabil.
KW  - PERVASIVE DEVELOPMENTAL DISORDER YOUNG-CHILDREN SPECTRUM DISORDERS PRESCHOOL-CHILDREN MENTAL-RETARDATION PSYCHOSOCIAL INTERVENTIONS METHODOLOGICAL CHALLENGES TRIAL PREDICTORS PARENTS Education, Special Rehabilitation
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 436NX Times Cited: 125 Cited Reference Count: 68 Howlin, Patricia Magiati, Iliana Charman, Tony Howlin, Patricia/A-7622-2011; Charman, Tony/A-2085-2014 Charman, Tony/0000-0003-1993-6549 127 AMER ASSOC INTELLECTUAL DEVELOPMENTAL DISABILITIES WASHINGTON AJIDD-AM J INTELLECT
PY  - 2009
SP  - 23-41
T2  - American Journal on Intellectual and Developmental Disabilities
TI  - Systematic Review of Early Intensive Behavioral Interventions for Children With Autism
UR  - &lt;Go to ISI&gt;://WOS:000265422000004http://www.aaiddjournals.org/doi/abs/10.1352/2009.114%3A23-41http://www.aaiddjournals.org/doi/pdf/10.1352/2009.114%3A23-41
VL  - 114
ER  -
TY  - JOUR
AB  - Traditional Chinese medicine (TCM) is frequently used to treat attention deficit hyperactivity disorders (ADHD) in children in China. 

However, until now there has been no strong evidence to prove that TCM has better efficacy than western medicine. 

In this systematic study of 34 studies published in the Chinese literature, the effectiveness of TCM in treating ADHD in children was examined and compared with methylphenidate (MPH), which is widely used to treat ADHD. 

It was found that TCM may have equal or better effectiveness than MPH. 

However, the lack of high-quality clinical trials to support this conclusion means that it is not currently possible to recommend any particular kind of TCM preparation for treating ADHD in children.
AD  - Lan,Y. Pharmaceutical Department, West China Second Hospital of Sichuan University, Chengdu, China.
AN  - 19589280
AU  - Lan,
AU  - Y.
AU  - Zhang,
AU  - L.
AU  - L.
AU  - Luo,
AU  - R.
DA  - May-Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/147323000903700340
DP  - Ovid Technologies
J2  - J Int Med Res
KW  - Adolescent *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] *Central Nervous System Stimulants/tu [Therapeutic Use] Child Humans *Medicine, Chinese Traditional *Methylphenidate/tu [Therapeutic Use] Publication Bias Time Factors Treatment
L1  - internal-pdf://0603489437/Lan-2009-Attention deficit hyperactivity disor.pdf
LA  - English
M3  - Comparative Study Meta-Analysis
N1  - Lan, Y Zhang, L-L Luo, R
PY  - 2009
SP  - 939-48
T2  - Journal of International Medical Research
TI  - Attention deficit hyperactivity disorder in children: comparative efficacy of traditional Chinese medicine and methylphenidate
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19589280
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19589280&amp;id=doi:&amp;issn=0300-0605&amp;isbn=&amp;volume=37&amp;issue=3&amp;spage=939&amp;pages=939-48&amp;date=2009&amp;title=Journal+of+International+Medical+Research&amp;atitle=Attention+deficit+hyperactivity+disorder+in+children%3A+comparative+efficacy+of+traditional+Chinese+medicine+and+methylphenidate.&amp;aulast=Lan&amp;pid=%3Cauthor%3ELan+Y%3C%2Fauthor%3E%3CAN%3E19589280%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://imr.sagepub.com/content/37/3/939.full.pdf
UR  - http://journals.sagepub.com/doi/pdf/10.1177/147323000903700340
VL  - 37
ER  -
TY  - JOUR
AB  - In this systematic and critical review of purely school based child sexual abuse prevention program efficacy studies, 22 studies meeting the inclusion criteria differed by target population, program implementation, and evaluation methodology 

Measured outcomes for children included knowledge, skills, emotion, risk perception, touch discrimination, reported response to actual threat or abuse, disclosure, maintenance of gains, and negative effects. 

Many studies had methodological limitations (e.g., sampling problems, lack of adequate control groups, lack of reliable and valid measures). 

However, most investigators claimed that their results showed significant impact in primary prevention (increasing all children&#039;s knowledge or awareness and/or abuse prevention skills). 

There vas little evidence of change in disclosure. There was limited follow-up evidence of actual use and effectiveness of prevention skills, and the evidence for maintenance of gains was mixed. 

Several programs reported some negative effects. Very few studies reported implementation fidelity, data, and no study reported cost-effectiveness. Implications for future research, policy, and practice are outlined.
AD  - [Topping, Keith J.; Barron, Ian G.] Univ Dundee, Sch Educ Social Work &amp; Community Educ, Dundee DD1 4HN, Scotland. Univ Dundee, Sch Educ Social Work &amp; Community Educ, Dundee DD1 4HN, Scotland. Topping, KJ (reprint author), Univ Dundee, Sch Educ Social Work &amp; Community Educ, Dundee DD1 4HN, Scotland. k.j.topping@dundee.ac.uk
AN  - WOS:000263690800013
AU  - Topping,
AU  - K.
AU  - J.
AU  - Barron,
AU  - I.
AU  - G.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.3102/0034654308325582
J2  - Rev. Educ. Res.
KW  - at-risk students law legal life span development social processes social development FOLLOW-UP DEVELOPMENTAL ISSUES VICTIMIZATION DISCLOSURE RECOMMENDATIONS MALTREATMENT METAANALYSIS KNOWLEDGE TEACHERS FAMILY Education &amp; Educational Research
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 411YQ Times Cited: 21 Cited Reference Count: 91 Topping, Keith J. Barron, Ian G. 21 SAGE PUBLICATIONS INC THOUSAND OAKS REV EDUC RES
PY  - 2009
SP  - 431-463
T2  - Review of Educational Research
TI  - School-Based Child Sexual Abuse Prevention Programs: A Review of Effectiveness
UR  - &lt;Go to ISI&gt;://WOS:000263690800013http://rer.sagepub.com/content/79/1/431http://rer.sagepub.com/content/79/1/431.full.pdf
VL  - 79
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
This review reports the incidence of hyperprolactinemia, its relationship with genotype, and prolactin-related side effects in children and adolescents treated with antipsychotics. 

**METHOD: **
Data on prolactin levels were available for haloperidol, pimozide, risperidone, olanzapine, clozapine, ziprasidone, and quetiapine. Twenty-nine studies were selected after a literature search in the English Medline/Embase/Psychinfo/EBM databases (1965 to August, 2008). 

**RESULTS: **
All antipsychotics, except clozapine, ziprasidone, and quetiapine, increase the mean prolactin level from baseline values of 8.0 ng/mL to 25-28 ng/mL after 4 weeks of treatment (reference range 0-15 ng/mL). The most and best data are available for risperidone. Five risperidone studies (n = 577) show an increase of prolactin level from 7.8 ng/mL to 17.7 ng/mL after 1 year of treatment, and two risperidone studies (n = 60) show an increase from 7.4 ng/mL to 24.9 ng/mL after 2 years of treatment. Aggregated over all antipsychotics, prolactin-related side effects, such as gynecomastia, galactorrhea, irregular menses, and sexual dysfunction, were reported by 4.8% of the children and adolescents. No data are available on bone mineral density in relation to antipsychotic-induced hyperprolactinemia in children and adolescents. Prolactin levels may be influenced by the genetic differences that influence prolactin metabolism and D2 dopamine receptor density. 

**CONCLUSION: **
Persistent elevation of prolactin for periods up to 2 years has been documented in maintenance treatment with risperidone. Very limited long-term data of pimozide, olanzapine, and quetiapine prohibit drawing conclusions for these antipsychotics. Systematic long-term observational studies, including specific questionnaires as well as physical examination, are needed to investigate prolactin-related side effects of antipsychotic treatment in children and adolescents.
AD  - Roke,Yvette. Symfora Group Psychiatric Center , Amersfoort, The Netherlands. y.roke@symfora.nl
AN  - 19702492
AU  - Roke,
AU  - Y.
AU  - van
AU  - Harten,
AU  - P.
AU  - N.
AU  - Boot,
AU  - A.
AU  - M.
AU  - Buitelaar,
AU  - J.
AU  - K.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1089/cap.2008.0120
DP  - Ovid Technologies
J2  - J Child Adolesc Psychopharmacol
KW  - Adolescent Age Factors *Antipsychotic Agents/ae [Adverse Effects] Antipsychotic Agents/tu [Therapeutic Use] Child Female Gynecomastia/ci [Chemically Induced] Gynecomastia/di [Diagnosis] Humans *Hyperprolactinemia/bl [Blood] Hyperprolactinemia/ci [Chemic
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Roke, Yvette van Harten, Peter N Boot, Annemieke M Buitelaar, Jan K Comment in: Evid Based Ment Health. 2010 May;13(2):54; PMID: 21856617
PY  - 2009
SP  - 403-14
T2  - Journal of Child and Adolescent Psychopharmacology
TI  - Antipsychotic medication in children and adolescents: a descriptive review of the effects on prolactin level and associated side effects
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=19702492 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:19702492&amp;id=doi:10.1089%2Fcap.2008.0120&amp;issn=1044-5463&amp;isbn=&amp;volume=19&amp;issue=4&amp;spage=403&amp;pages=403-14&amp;date=2009&amp;title=Journal+of+Child+%26+Adolescent+Psychopharmacology&amp;atitle=Antipsychotic+medication+in+children+and+adolescents%3A+a+descriptive+review+of+the+effects+on+prolactin+level+and+associated+side+effects.&amp;aulast=Roke&amp;pid=%3Cauthor%3ERoke+Y%3C%2Fauthor%3E%3CAN%3E19702492%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://online.liebertpub.com/doi/abs/10.1089/cap.2008.0120
UR  - http://online.liebertpub.com/doi/abs/10.1089/cap.2008.0120?url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org&amp;rfr_dat=cr_pub%3Dpubmed&amp;
VL  - 19
ER  -
TY  - JOUR
AB  - **Background:**
Attention-deficit hyperactivity disorder (ADHD) is increasingly recognised as occurring in people with intellectual disability (ID), although treatment of ADHD in this population has not been tested widely. Amfetamine has been used to treat ADHD in people with and without ID, although the evidence for its efficacy in people with ID is unclear.

**Objectives:** 
To examine the effectiveness of amfetamine for the treatment of attention deficit hyperactivity disorder in people with intellectual disabilities.

**Search methods:** 
MEDLINE, PsycINFO, EMBASE, AMED, ISI Web of Science and WorldCat Dissertations were searched using an extensive list of synonyms for ADHD and ID. CENTRAL, Current Controlled Trials meta-register (mRCT), CenterWatch, NHS National Research Register, clinicaltrials.gov were searched in August 2007. Pharmaceutical companies and experts in the field were contacted. Reference lists of review articles were examined and citation searches were performed in ISI Web of Knowledge.

**Selection criteria:** 
All randomised controlled studies, both published and unpublished, in any language, in which children or adults with ADHD and ID were treated with amfetamine.

**Data collection and analysis:** 
Data were extracted independently by two reviewers using a standardised extraction sheet. Risk of bias was assessed by two authors using a standardised framework. Meta-analyses were planned but were not performed due to a lack of suitable studies.

**Main results:** 
Only one study was suitable for inclusion. This was a cross-over study in 15 children with ADHD, ID and Fragile X syndrome. Duration of treatment was only one week. No significant difference was reported between amfetamine and placebo for any of the ADHD measures, but significantly more side effects were reported while taking amfetamine, mainly mood lability and irritability.

**Authors&#039; conclusions:** 
There is very little evidence for the effectiveness of amfetamine for ADHD in people with ID . Prescribing in this population is based on extrapolation of research in people without ID. More research into effectiveness and tolerability is urgently needed.
AN  - CD007009
AU  - Thomson,
AU  - A.
AU  - Maltezos,
AU  - S.
AU  - Paliokosta,
AU  - E.
AU  - Xenitidis,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007009
KW  - Amphetamine [therapeutic use]
KW  - Attention Deficit Disorder with Hyperactivity [drug therapy]
KW  - Central Nervous System Stimulants [therapeutic use]
KW  - Fragile X Syndrome [complications]
KW  - Mentally Disabled Persons [psychology]
KW  - Methylphenidate [therapeutic use]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2009
T2  - Cochrane Database of Systematic Reviews
TI  - Amfetamine for attention deficit hyperactivity disorder in people with intellectual disabilities
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007009.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007009.pub2/asset/CD007009.pdf?v=1&amp;t=iw7imtly&amp;s=1d3a5548ff5385d6321889f74e70d4d58cd5cc08
ER  -
TY  - JOUR
AB  - To evaluate the efficacy of selective serotonin reuptake inhibitors (SSRIs) in children and adolescents with depressive disorder, the main electronic databases and the reference lists of retrieved articles and reviews were searched up to January 2007. 

Randomized controlled studies (RCT) were assessed for methodological quality, taking into consideration the specific diagnostic and severity evaluation tools used, and a meta-analysis on the efficacy of SSRIs compared placebo was undertaken. 

In all, 13 studies were included, covering a total of 2530 children and adolescents. Eleven studies met the criteria for inclusion in the meta-analysis. The pooled odds ratio was 1.57 (95% C.I. 1.29-1.91). Only fluoxetine appeared to offer a moderately significant benefit profile (OR=2.39). 

All studies differed in diagnostic tools and primary efficacy measures. SSRI treatment, especially with fluoxetine, may be effective on child and adolescent depression. 

Nevertheless, additional RCTs with sound methodological designs, validated diagnostic instruments, large sample sizes, and consistent outcomes are necessary to determine the role of SSRIs, alone or in combination with psychological interventions in the treatment of depression in children and adolescents.
AD  - Usala,Tatiana. Child NeuroPsychiatry, Department of Neurosciences, University of Cagliari Via Ospedale 119, 09124 Cagliari, Italy.
AN  - 17662579
AU  - Usala,
AU  - T.
AU  - Clavenna,
AU  - A.
AU  - Zuddas,
AU  - A.
AU  - Bonati,
AU  - M.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.euroneuro.2007.06.001
DP  - Ovid Technologies
J2  - Eur Neuropsychopharmacol
KW  - Adolescent Child *Depressive Disorder/dt [Drug Therapy] Female Humans Male Randomized Controlled Trials as Topic Research Design Serotonin Uptake Inhibitors/ae [Adverse Effects] *Serotonin Uptake Inhibitors/tu [Therapeutic Use] Treatment Outcome 0 (Sero
LA  - English
M3  - Meta-Analysis Review
N1  - Usala, Tatiana Clavenna, Antonio Zuddas, Alessandro Bonati, Maurizio
PY  - 2008
SP  - 62-73
T2  - European Neuropsychopharmacology
TI  - Randomised controlled trials of selective serotonin reuptake inhibitors in treating depression in children and adolescents: a systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17662579 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17662579&amp;id=doi:&amp;issn=0924-977X&amp;isbn=&amp;volume=18&amp;issue=1&amp;spage=62&amp;pages=62-73&amp;date=2008&amp;title=European+Neuropsychopharmacology&amp;atitle=Randomised+controlled+trials+of+selective+serotonin+reuptake+inhibitors+in+treating+depression+in+children+and+adolescents%3A+a+systematic+review+and+meta-analysis.&amp;aulast=Usala&amp;pid=%3Cauthor%3EUsala+T%3C%2Fauthor%3E%3CAN%3E17662579%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0924977X07001253/1-s2.0-S0924977X07001253-main.pdf?_tid=dda58d0a-18db-11e5-9fd2-00000aab0f27&amp;acdnat=1434977010_ca2ba27d9542f8a0032faefe64456cfa
VL  - 18
ER  -
TY  - JOUR
AB  - **INTRODUCTION: **
This meta-analysis compares effect-sizes of methylphenidate and psychosocial treatments and their combination on ADHD, concurrent oppositional, conduct symptoms, social behaviors and academic functioning. 

**METHOD: **
Several databases (PubMed, PsycInfo, ISI Web of Science) were searched for articles published between 1985 and September 2006. Inclusion criteria were: a diagnosis of ADHD; age from 6-12 years; a randomized controlled treatment design; efficacy established with parent and teacher rating scales; psychosocial treatments used were described as behavioral or cognitive-behavioral; the methylphenidate treatment was short-acting; and finally, treatment was conducted in a clinical setting. 

**RESULTS: **
ADHD outcomes showed large mean weighted effect-sizes for both methylphenidate and combined treatments, psychosocial treatments had a moderate mean weighted effect-size; a similar pattern emerged for oppositional and conducted behavior symptoms. Social behavior outcomes showed comparable moderate mean weighted effect-sizes for all treatments, while on academic functioning, all treatments had low mean weighted effect-sizes. There was no correlation between duration of psychosocial treatment and effect-size. 

**CONCLUSIONS: **
Both methylphenidate and psychosocial treatments are effective in reducing ADHD symptoms. However, psychosocial treatment yields smaller effects than both other treatment conditions. Psychosocial treatment has no additional value to methylphenidate for the reduction of ADHD and teacher rated ODD symptoms. However, for social behavior and parent rated ODD the three treatments were equally effective. For improvement of academic functioning no treatment was effective.
AD  - Van der Oord,S. Department of Clinical Psychology, University of Amsterdam, Roeterstraat 15, 1018 WB Amsterdam, The Netherlands. s.vanderoord@uva.nl
AN  - 18068284
AU  - Van
AU  - der
AU  - Oord,
AU  - S.
AU  - Prins,
AU  - P.
AU  - J.
AU  - Oosterlaan,
AU  - J.
AU  - Emmelkamp,
AU  - P.
AU  - M.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2007.10.007
DP  - Ovid Technologies
J2  - Clin Psychol Rev
KW  - *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] Attention Deficit Disorder with Hyperactivity/px [Psychology] Attention Deficit and Disruptive Behavior Disorders/dt [Drug Therapy] Attention Deficit and Disruptive Behavior Disorders/px [
LA  - English
M3  - Meta-Analysis
N1  - Van der Oord, S Prins, P J M Oosterlaan, J Emmelkamp, P M G Comment in: Evid Based Ment Health. 2009 Feb;12(1):18; PMID: 19176777
PY  - 2008
SP  - 783-800
T2  - Clinical Psychology Review
TI  - Efficacy of methylphenidate, psychosocial treatments and their combination in school-aged children with ADHD: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18068284 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18068284&amp;id=doi:&amp;issn=0272-7358&amp;isbn=&amp;volume=28&amp;issue=5&amp;spage=783&amp;pages=783-800&amp;date=2008&amp;title=Clinical+Psychology+Review&amp;atitle=Efficacy+of+methylphenidate%2C+psychosocial+treatments+and+their+combination+in+school-aged+children+with+ADHD%3A+a+meta-analysis.&amp;aulast=Van+der+Oord&amp;pid=%3Cauthor%3EVan+der+Oord+S%3C%2Fauthor%3E%3CAN%3E18068284%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735807001869/1-s2.0-S0272735807001869-main.pdf?_tid=600a5578-1972-11e5-a3b8-00000aacb361&amp;acdnat=1435041653_4a2e126a739f6335b07ce61b274a1765
VL  - 28
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Youth violence and related aggressive behaviors have become serious public health issues with physical, economic, social, and psychological impacts and consequences. This study identified and evaluated the characteristics of successful school-based violence prevention programs. 

**METHODS: **
Twenty-six randomized controlled trial (RCT), school-based studies that were designed to reduce externalizing, aggressive, and violent behavior between the 1st and 11th grades were analyzed for assessing the effects of 5 program characteristics by comparing results of intervention groups to control groups (no intervention) after intervention using a meta-analysis. Electronic databases and bibliographies were systematically searched, and a standardized mean difference was used for analysis. 

**RESULTS:**
There was no significant difference between interventions, although programs that used non-theory-based interventions, focused on at-risk and older children, and employed intervention specialists had slightly stronger effects in reducing aggression and violence. Interventions using a single approach had a mild positive effect on decreasing aggressive and violent behavior (effect size =-0.15, 95% CI =-0.29 to -0.02, p = .03). 

**CONCLUSIONS: **
Unlike previous individual study findings, this meta-analysis did not find any differential effects for 4 of the 5 program characteristics. In addition, the significant effect noted was contrary to expectation, exemplifying the complexity of identifying effective program strategies. This study adds to the current literature by assessing the program characteristics of RCT studies in an effort to determine what factors may affect school-based violence prevention program success.
AD  - Park-Higgerson,Hyoun-Kyoung. The Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA.
AN  - 18786039
AU  - Park-Higgerson,
AU  - H.
AU  - K.
AU  - Perumean-Chaney,
AU  - S.
AU  - E.
AU  - Bartolucci,
AU  - A.
AU  - A.
AU  - Grimley,
AU  - D.
AU  - M.
AU  - Singh,
AU  - K.
AU  - P.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/j.1746-1561.2008.00332.x
DP  - Ovid Technologies
J2  - J Sch Health
KW  - Adolescent Adolescent Behavior Age Factors Child Child Behavior Humans Program Evaluation Randomized Controlled Trials as Topic *School Health Services *Violence/pc [Prevention &amp; Control]
L1  - internal-pdf://3395604900/Park-Higgerson-2008-The evaluation of school-b.pdf
LA  - English
M3  - Evaluation Studies Meta-Analysis
N1  - Park-Higgerson, Hyoun-Kyoung Perumean-Chaney, Suzanne E Bartolucci, Alfred A Grimley, Diane M Singh, Karan P
PY  - 2008
SP  - 465-79; quiz 518-20
T2  - Journal of School Health
TI  - The evaluation of school-based violence prevention programs: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18786039
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18786039&amp;id=doi:10.1111%2Fj.1746-1561.2008.00332.x&amp;issn=0022-4391&amp;isbn=&amp;volume=78&amp;issue=9&amp;spage=465&amp;pages=465-79%3B+quiz+518-20&amp;date=2008&amp;title=Journal+of+School+Health&amp;atitle=The+evaluation+of+school-based+violence+prevention+programs%3A+a+meta-analysis.&amp;aulast=Park-Higgerson&amp;pid=%3Cauthor%3EPark-Higgerson+HK%3C%2Fauthor%3E%3CAN%3E18786039%3C%2FAN%3E%3CDT%3EEvaluation+Studies%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1746-1561.2008.00332.x/asset/j.1746-1561.2008.00332.x.pdf?v=1&amp;t=ib3joid5&amp;s=7502e65f8c90c7b962a0a71e1dd5b5889d329201
UR  - http://onlinelibrary.wiley.com/store/10.1111/j.1746-1561.2008.00332.x/asset/j.1746-1561.2008.00332.x.pdf?v=1&amp;t=j8yfufmb&amp;s=413aba3f1b22f85fbea1e2b96318fd61c2e2bb4d
VL  - 78
ER  -
TY  - JOUR
AB  - **PURPOSE: **
This systematic review examined the hypothesis that school institutional factors influence young people&#039;s use of drugs. We aimed to (1) identify the effect of school-level changes on drug use and (2) explore the possible mechanisms by which school-level influences on individual drug use might occur. 

**METHODS: **
Systematic review. Experimental/quasi-experimental studies of &quot;whole-school&quot; drug prevention interventions and longitudinal observational studies on the association between school-level and individual-level school-related exposures and drug use were included. Experimental studies were included because they are the most reliable available source of evidence about causation. Observational studies of school-level and individual-level school-related exposures were included with the aim of providing evidence about a wider range of possible school-level effects and how school-level influences might be mediated by individual-level factors. 

**RESULTS: **
Experimental studies suggested that changes to the school social environment that increase student participation, improve relationships and promote a positive school ethos may be associated with reduced drug use. School-level and individual-level observational studies consistently reported that disengagement and poor teacher-student relationships were associated with drug use and other risky health behaviors. 

**CONCLUSIONS: **
There is evidence of school effects on young people&#039;s drug use. Interventions that promote a positive school ethos and reduce student disaffection may be an effective complement to drug prevention interventions addressing individual knowledge, skills, and peer norms. Such approaches should now be piloted in a wider range of settings. Further research is also needed to explore mechanisms by which schools may influence young people&#039;s drug use.
AN  - 18295128
AU  - Fletcher,
AU  - A.
AU  - Bonell,
AU  - C.
AU  - Hargreaves,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jadohealth.2007.09.020
L1  - internal-pdf://1733213749/Fletcher-2008-School effects on young people&#039;s.pdf
PY  - 2008
SP  - 209-20
TI  - School effects on young people&#039;s drug use: a systematic review of intervention and observational studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=18295128
VL  - 42
ER  -
TY  - JOUR
AB  - **Background: **
Adolescence is a transition period that involves physiological, psychological, and social changes. Emotional problems such as symptoms of anxiety and depression may develop due to these changes. Although many of these problems may not meet diagnostic thresholds, they may develop into more severe disorders and may impact on functioning. However, there are barriers that may make it difficult for adolescents to receive help from health professionals for such problems, one of which is the limited availability of formal psychological therapy. One way of increasing access to help for such problems is through self help technology (i.e. delivery of psychological help through information technology or paper based formats). Although there is a significant evidence base concerning self help in adults, the evidence base is much weaker in adolescents. This study aims to examine the effectiveness of self help technology for the treatment of emotional problems in adolescents by conducting a systematic review of randomized and quasi-experimental evidence. 

**Methods: **
Five major electronic databases were searched: Medline, PsycInfo, Embase, Cochrane Controlled Trials Register and CINAHL. In addition, nine journals were handsearched and the reference lists of all studies were examined for any additional studies. Fourteen studies were identified. Effect sizes were calculated across 3 outcome measures: attitude towards self (e.g. self esteem); social cognition (e.g. self efficacy); and emotional symptoms (i.e. depression and anxiety symptoms). 

**Results: **
Meta analysis showed small, non-significant effect size for attitude towards self (ES = -0.14, 95% CI = -0.72 to 0.43), a medium, non-significant effect size for social cognition (ES = -0.49, 95% CI = -1.23 to 0.25) and a medium, non-significant effect size for emotional symptoms (ES = -0.47, 95% CI = -1.00 to 0.07). However, these findings must be considered preliminary, because of the small number of studies, their heterogeneity, and the relatively poor quality of the studies. 

**Conclusion:** 
At present, the adoption of self help technology for adolescents with emotional problems in routine clinical practice cannot be recommended. There is a need to conduct high quality randomised trials in clearly defined populations to further develop the evidence base before implementation. &copy; 2008 Ahmead and Bower; licensee BioMed Central Ltd.
AD  - (Ahmead) School of Public Health, Al-Quds University, Jerusalem, Israel (Bower) NPCRDC, University of Manchester, Williamson Building, Manchester M13 9PL, United Kingdom P. Bower, NPCRDC, University of Manchester, Williamson Building, Manchester M13 9PL, United Kingdom. E-mail: peter.bower@manchester.ac.uk
AU  - Ahmead,
AU  - M.
AU  - Bower,
AU  - P.
DA  - 23 Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/1753-2000-2-20
DP  - Ovid TechUI - 2008383212
KW  - adolescent anxiety child psychiatry Cinahl clinical effectiveness clinical practice clinical trial Cochrane Library cognition computer system data base depression Embase emotional disorder/th [Therapy] evidence based medicine human information technolog
LA  - English
M3  - Review
PY  - 2008
T2  - Child and Adolescent Psychiatry and Mental Health
TI  - The effectiveness of self help technologies for emotional problems in adolescents: A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed8&amp;AN=2008383212 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1186%2F1753-2000-2-20&amp;issn=1753-2000&amp;isbn=&amp;volume=2&amp;issue=&amp;spage=20&amp;pages=&amp;date=2008&amp;title=Child+and+Adolescent+Psychiatry+and+Mental+Health&amp;atitle=The+effectiveness+of+self+help+technologies+for+emotional+problems+in+adolescents%3A+A+systematic+review&amp;aulast=Ahmead&amp;pid=%3Cauthor%3EAhmead+M.%3C%2Fauthor%3E%3CAN%3E2008383212%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3Ehttp://www.capmh.com/content/pdf/1753-2000-2-20.pdf
VL  - 2
ER  -
TY  - JOUR
AB  - Sexual abuse in children not only occurs with alarming frequency, it also potentially leads to deleterious consequences for victims. Previous narrative reviews have touted the benefits of including the nonoffending caregiver in child sexual treatment.
 
**Objective:** 
A meta-analysis is conducted to determine the effects of parent-involved treatment in four major child symptom areas: internalizing, externalizing, sexualized behaviors, and posttraumatic stress. 

**Method:** 
Only comparison/control group studies are included. Participant, treatment, and methodological characteristics of studies are coded, as well as information to calculate effect sizes. An overall effect size is calculated, though the small number of studies precluded moderator analysis. 

**Results:** 
Seven studies are located that met the inclusion criteria. At posttest, treatment had small effects in the four outcome domains over alternative interventions and was reduced still further at follow-up. 

**Conclusion:** 
Parent-involved treatment confers some advantage over comparison conditions (typically child-only treatment). (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Corcoran, Jacqueline: jcorcora@vcu.edu Corcoran, Jacqueline: School of Social Work, Northern Virginia Branch, Virginia Commonwealth University, 6295 Edsall Road Suite 210, Alexandria, VA, US, 22312, jcorcora@vcu.edu Corcoran, Jacqueline: Virginia Commonwealth University, Alexandria, VA, US Pillai, Vijayan: Virginia Commonwealth University, Alexandria, VA, US
AN  - 2008-12039-010
AU  - Corcoran,
AU  - J.
AU  - Pillai,
AU  - V.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1049731507313980
DP  - Ovid Technologies
KW  - parent-involved treatment, child sexual abuse, foster parents *Child Abuse *Foster Parents *Parental Involvement *Sexual Abuse *Treatment Stress Health &amp; Mental Health Treatment &amp; Prevention [3300] Human
LA  - English
M3  - Meta Analysis
N1  - Special Issue on the Florida Behavior Analysis Services Program
PY  - 2008
SP  - 453-464
T2  - Research on Social Work Practice
TI  - A meta-analysis of parent-involved treatment for child sexual abuse
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc6&amp;AN=2008-12039-010 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1049731507313980&amp;issn=1049-7315&amp;isbn=&amp;volume=18&amp;issue=5&amp;spage=453&amp;pages=453-464&amp;date=2008&amp;title=Research+on+Social+Work+Practice&amp;atitle=A+meta-analysis+of+parent-involved+treatment+for+child+sexual+abuse.&amp;aulast=Corcoran&amp;pid=%3Cauthor%3ECorcoran%2C+Jacqueline%3C%2Fauthor%3E%3CAN%3E2008-12039-010%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rsw.sagepub.com/content/18/5/453http://rsw.sagepub.com/content/18/5/453.full.pdf
VL  - 18
ER  -
TY  - JOUR
AB  - Children and adolescents in the U.S. and worldwide are commonly exposed to traumatic events, yet practitioners treating these young people to reduce subsequent psychological harm may not be aware of-or use-interventions based on the best available evidence. 

This systematic review evaluated interventions commonly used to reduce psychological harm among children and adolescents exposed to traumatic events. Guide to Community Preventive Services (Community Guide) criteria were used to assess study design and execution. 

Meta-analyses were conducted, stratifying by traumatic exposures. Evaluated interventions were conducted in high-income economies, published up to March 2007. Subjects in studies were &lt;or=21 years of age, exposed to individual/mass, intentional/unintentional, or manmade/natural traumatic events. 

The seven evaluated interventions were individual cognitive-behavioral therapy, group cognitive behavioral therapy, play therapy, art therapy, psychodynamic therapy, and pharmacologic therapy for symptomatic children and adolescents, and psychological debriefing, regardless of symptoms. 

The main outcome measures were indices of depressive disorders, anxiety and posttraumatic stress disorder, internalizing and externalizing disorders, and suicidal behavior. Strong evidence (according to Community Guide rules) showed that individual and group cognitive-behavioral therapy can decrease psychological harm among symptomatic children and adolescents exposed to trauma. 

Evidence was insufficient to determine the effectiveness of play therapy, art therapy, pharmacologic therapy, psychodynamic therapy, or psychological debriefing in reducing psychological harm. 

Personnel treating children and adolescents exposed to traumatic events should use interventions for which evidence of effectiveness is available, such as individual and group cognitive-behavior therapy. Interventions should be adapted for use in diverse populations and settings. 

Research should be pursued on the effectiveness of interventions for which evidence is currently insufficient.
AD  - Wethington,Holly R. National Center for Health Marketing, CDC, Atlanta, Georgia 30333, USA.
AN  - 18692745
AU  - Wethington,
AU  - H.
AU  - R.
AU  - Hahn,
AU  - R.
AU  - A.
AU  - Fuqua-Whitley,
AU  - D.
AU  - S
AU  - Sipe,
AU  - T.
AU  - A.
AU  - Crosby,
AU  - A.
AU  - E.
AU  - Johnson,
AU  - R.
AU  - L.
AU  - Liberman,
AU  - A.
AU  - M.
AU  - Moscicki,
AU  - E.
AU  - Price,
AU  - L.
AU  - M.
AU  - Tuma,
AU  - F.
AU  - K.
AU  - Kalra,
AU  - G.
AU  - Chattopadhyay,
AU  - S.
AU  - K.
AU  - Task
AU  - Force
AU  - on
AU  - Community&nbsp;Preventive
AU  - Services
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.amepre.2008.06.024.
DP  - Ovid Technologies
J2  - Am J Prev Med
KW  - Adolescent Age Factors Art Therapy Behavior Therapy Child Cognitive Therapy Female Humans Male Play Therapy Program Development *Program Evaluation Stress Disorders, Post-Traumatic/dt [Drug Therapy] *Stress Disorders, Post-Traumatic/pc [Prevention &amp; Con
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Wethington, Holly R Hahn, Robert A Fuqua-Whitley, Dawna S Sipe, Theresa Ann Crosby, Alex E Johnson, Robert L Liberman, Akiva M Moscicki, Eve Price, Leshawndra N Tuma, Farris K Kalra, Geetika Chattopadhyay, Sajal K Task Force on Community Preventive Services Comment in: Am J Prev Med. 2008 Oct;35(4):398-400; PMID: 18779033
PY  - 2008
SP  - 287-313
T2  - American Journal of Preventive Medicine
TI  - The effectiveness of interventions to reduce psychological harm from traumatic events among children and adolescents: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18692745
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18692745&amp;id=doi:10.1016%2Fj.amepre.2008.06.024&amp;issn=0749-3797&amp;isbn=&amp;volume=35&amp;issue=3&amp;spage=287&amp;pages=287-313&amp;date=2008&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=The+effectiveness+of+interventions+to+reduce+psychological+harm+from+traumatic+events+among+children+and+adolescents%3A+a+systematic+review.&amp;aulast=Wethington&amp;pid=%3Cauthor%3EWethington+HR%3C%2Fauthor%3E%3CAN%3E18692745%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S074937970800528X/1-s2.0-S074937970800528X-main.pdf?_tid=f3f03bbe-167e-11e5-8e64-00000aacb35f&amp;acdnat=1434717201_77694632b0121a431445be98dd200df8
VL  - 35
ER  -
TY  - JOUR
AB  - **Background:** 
A strong and consistent relationship has been observed between relative poverty and poor child health and well-being even among rich nations. This review set out to examine evidence that additional monies provided to poor or disadvantaged families may benefit children by reducing relative poverty and thereby improving children&#039;s health, well-being and educational attainment.

**Objectives:** 
To assess the effectiveness of direct provision of additional monies to socially or economically disadvantaged families in improving children&#039;s health, well-being and educational attainment.

**Search methods:** 
In total, 10 electronic databases were searched, including CENTRAL (searched Issue 3, 2006), MEDLINE (searched 1966 to May 2006), EconLit (searched 1969 to June 2006) and PsycINFO (searched 1872 to June 2006), together with three libraries of working papers (MDRC, SSRN, SRDC). The general search strategy was [terms for income and financial benefits] and [paediatric terms] and [RCT filter].

**Selection criteria:** 
Studies selected provided money to relatively poor families (which included a child under the age of 18 or a pregnant woman), were randomised or quasi-randomised, measured outcomes related to child health or well-being and were conducted in a high income country.

**Data collection and analysis:** 
Titles and abstracts identified in the search were independently assessed for eligibility by two reviewers. Data were extracted and entered into Review Manager software (RevMan), synthesised and presented in both written and graphical form (forest plots).

**Main results:** 
Nine trials including more than 25,000 participants were included in this review. No effect was observed on child health, measures of child mental health or emotional state. Non-significant effects favouring the intervention group were seen for child cognitive development and educational achievement, and a non-significant effect favouring controls in rates of teenage pregnancy.

**Authors&#039; conclusions:** 
The review set out to examine the potential of financial support to poor families to improve circumstances for children. However, on the basis of current evidence we cannot state unequivocally whether financial benefits delivered as an intervention are effective at improving child health or well-being in the short term. Our conclusions are limited by the fact that most of the studies had small effects on total household income and that, while no conditions were attached to how money was spent, all studies included strict conditions for receipt of payments. We note particular concerns by some authors that sanctions and conditions (such as working hours) placed on families may increase family stress.
AN  - CD006358
AU  - Lucas,
AU  - P.
AU  - McIntosh,
AU  - K.
AU  - Petticrew,
AU  - M.
AU  - Roberts,
AU  - H.
AU  - M.
AU  - Shiell,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2008.9
KW  - Developed Countries
KW  - Financial Support
KW  - Child Development
KW  - Child Welfare [economics]
KW  - Educational Status
KW  - Poverty [economics]
KW  - Randomized Controlled Trials as Topic
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2008
TI  - Financial benefits for child health and well-being in low income or socially disadvantaged families in developed world countries
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006358.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006358.pub2/asset/CD006358.pdf?v=1&amp;t=iw7jhxtb&amp;s=da155b1e672b0762000a5b5946d4b4244c8c5058
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
The aim of this study was to conduct a systematic review of the efficacy of music therapy (MT) on pain and anxiety in children undergoing clinical procedures. 

**METHODS: **
We searched 16 electronic databases of published and unpublished studies, subject bibliographies, reference lists of relevant articles, and trials registries. Two reviewers independently screened 4559 citations and reviewed the full manuscript of 393 studies. Nineteen studies met the inclusion criteria: randomized controlled trial, children aged 1 month to 18 years were examined, music was used as an intervention, and the study measured pain or anxiety. Music therapy was considered active if a music therapist was involved and music was used as a medium for interactive communication. Passive music therapy was defined as listening to music without the involvement of a music therapist. 

**RESULTS: **
The 19 included trials involved 1513 subjects. The methodological quality of the studies was generally poor. Overall, MT showed a significant reduction in pain and anxiety (standardized mean difference [SMD] -0.35; 95% confidence interval [CI], -0.55 to -0.14; 9 studies; N = 704; I(2) = 42%). When analyzed by outcome, MT significantly reduced anxiety (SMD -0.39; 95% CI, -0.76 to -0.03; 5 studies; n = 284; I(2) = 52.4%) and pain (SMD -0.39; 95% CI, -0.66 to -0.11; 5 studies; N = 465; I(2) = 49.7%). There was no evidence of publication bias. 

**CONCLUSIONS:** 
Music is effective in reducing anxiety and pain in children undergoing medical and dental procedures. Music can be considered an adjunctive therapy in clinical situations that produce pain or anxiety.
AD  - Klassen,Jeffrey A. From the Alberta Research Center for Child Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Canada.
AN  - 18355741
AU  - Klassen,
AU  - J.
AU  - A.
AU  - Liang,
AU  - Y.
AU  - Tjosvold,
AU  - L.
AU  - Klassen,
AU  - T.
AU  - P.
AU  - Hartling,
AU  - L.
DA  - Mar-Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.acpain.2008.05.038
DP  - Ovid Technologies
J2  - Ambul Pediatr
KW  - Anxiety/et [Etiology] *Anxiety/pc [Prevention &amp; Control] Child Diagnostic Techniques and Procedures/ae [Adverse Effects] Humans *Music Therapy Pain/et [Etiology] *Pain/pc [Prevention &amp; Control] Randomized Controlled Trials as Topic Surgical Procedures
LA  - English
M3  - Review
N1  - Klassen, Jeffrey A Liang, Yuanyuan Tjosvold, Lisa Klassen, Terry P Hartling, Lisa Comment in: J Evid Based Dent Pract. 2009 Dec;9(4):213-4; PMID: 19913737
PY  - 2008
SP  - 117-28
T2  - Ambulatory Pediatrics
TI  - Music for pain and anxiety in children undergoing medical procedures: a systematic review of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18355741
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18355741&amp;id=doi:10.1016%2Fj.ambp.2007.12.005&amp;issn=1530-1567&amp;isbn=&amp;volume=8&amp;issue=2&amp;spage=117&amp;pages=117-28&amp;date=2008&amp;title=Ambulatory+Pediatrics&amp;atitle=Music+for+pain+and+anxiety+in+children+undergoing+medical+procedures%3A+a+systematic+review+of+randomized+controlled+trials.&amp;aulast=Klassen&amp;pid=%3Cauthor%3EKlassen+JA%3C%2Fauthor%3E%3CAN%3E18355741%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1530156707002857/1-s2.0-S1530156707002857-main.pdf?_tid=0516db10-167e-11e5-ad19-00000aab0f6c&amp;acdnat=1434716801_e08e6ec1abf587412809bfa440739c50
VL  - 8
ER  -
TY  - JOUR
AB  - Few studies have examined the effects of varying the level of intensity of a parenting intervention in the treatment of conduct problems in children. In particular, it is unclear whether group parenting interventions that incorporate adjunctive cognitive interventions designed to reduce parental stress add to the efficacy and durability of effects of standard parenting skills training. Adjunctive interventions designed to reduce depression, stress, anger management problems or cognition biases, delivered in group settings, have the potential to augment parenting skills training. There is some empirical support for adjunctive interventions, but there are also conflicting findings. This study reviews the data from existing randomized controlled trials evaluating the effectiveness of group based cognitively enhanced behavioral parenting programs for reducing children&#039;s disruptive behavior and parent distress. The findings show the potential that such interventions have in reducing children&#039;s disruptive behavior and draw some lines for future integration of the cognitive components in behavioral parent training. (PsycINFO Database Record (c) 2014 APA, all rights reserved) (journal abstract).
AD  - Gavita, Oana: oanagavita@psychology.ro Gavita, Oana, oanagavita@psychology.ro Gavita, Oana: Babes-Bolyai University, Cluj-Napoca, Romania Joyce, Marie: Australian Catholic University, Quality of Life and Social Justice Flagship, Institute for the Advancement of Research, Melbourne, VIC, Australia
AN  - 2008-14214-003
AU  - Gavita,
AU  - O.
AU  - Joyce,
AU  - M.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Har ikke DOI: http://www.international-coaching.org/files/pagini/review.pdf
DP  - Ovid Technologies
KW  - group cognitively enhanced behavioral based parent programs, disruptive behavior, childhood development *Behavior Problems *Childhood Development *Group Dynamics *Parent Training Cognition Behavior Disorders &amp; Antisocial Behavior [3230] Health &amp; Mental
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2008
SP  - 185-199
T2  - Journal of Cognitive and Behavioral Psychotherapies
TI  - A review of the effectiveness of group cognitively enhanced behavioral based parent programs designed for reducing disruptive behavior in children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc6&amp;AN=2008-14214-003 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=1584-7101&amp;isbn=&amp;volume=8&amp;issue=2&amp;spage=185&amp;pages=185-199&amp;date=2008&amp;title=Journal+of+Cognitive+and+Behavioral+Psychotherapies&amp;atitle=A+review+of+the+effectiveness+of+group+cognitively+enhanced+behavioral+based+parent+programs+designed+for+reducing+disruptive+behavior+in+children.&amp;aulast=Gavita&amp;pid=%3Cauthor%3EGavita%2C+Oana%3C%2Fauthor%3E%3CAN%3E2008-14214-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 8
ER  -
TY  - JOUR
AB  - **Background **
Many studies document a robust and consistent relationship between gang membership and elevated delinquency, with gang members disproportionately involved in crime compared to non- gang peers. Research also indicates that both delinquent youth and youth who join gangs often show a wide range of deficient or distorted social- cognitive processes compared to non- delinquent peers. Cognitive-behavioural interventions are designed to address cognitive deficits in order to reduce maladaptive or dysfunctional behaviour, and studies have documented their positive impact on a number of behavioural and psychological disorders among children and youth. 

**Objectives **
To determine the effectiveness of cognitive- behavioural interventions for preventing youth gang involvement for children and young people ( ages 7-16). 

**Search strategy** 
Electronic searches of ASSIA, CINAHL, CJA, Cochrane Library, Dissertations Abstracts A, EMBASE, ERIC, IBSS, LILACs, LexisNexis Butterworths, MEDLINE, NCJR Service Abstracts Database, PsycINFO, and Sociological Abstracts, to April 2007. Reviewers contacted relevant organisations, individuals, and list- servs and searched pertinent websites and reference lists. 

**Selection criteria **
All randomised controlled trials or quasi- randomised controlled trials of interventions with a cognitive- behavioural intervention as the majority component, delivered to youth and children aged 7- 16 not involved in a gang. 

**Datacollection and analysis **
Searching yielded 2,284 unduplicated citations, 2,271 of which were excluded as irrelevant based on title and abstract. One was excluded following personal communication with investigators. One citation, of a large randomised prevention trial, awaits assessment; personal communication with study authors yielded unpublished reports addressing gang outcomes, but insufficient detail precluded determining inclusion status. Seven remaining reports were excluded as irrelevant because they were narrative reviews or descriptions of programs without evaluations, did not address a gang prevention programme, or did not address a gang prevention program that included a cognitive- behavioural intervention. The remaining four full- text reports excluded because of study design, leading to O included studies. 

**Main results **
No randomised controlled trials or quasi- randomised controlled trials were identified. Authors&#039; conclusions No evidence from randomised controlled trials or quasi- randomised controlled trials exists regarding the effectiveness of cognitive-behavioural interventions for gang prevention. Four evaluations of Gang Resistance Education and Training ( GREAT) have been conducted, two of which were part of a US national evaluation, but all were excluded based on study design. Reviewers conclude there is an urgent need for rigorous primary evaluations of cognitive- behavioural interventions for gang prevention to develop this research field and guide future gang prevention programmes and policies.
AD  - [Montgomery, P.] Univ Oxford, Ctr Evidence Based Intervent, Oxford OX1 2ER, England. Montgomery, P (reprint author), Univ Oxford, Ctr Evidence Based Intervent, Barnett House 32 Wellington Sq, Oxford OX1 2ER, England. paul.montgomery@socres.ox.ac.uk
AN  - WOS:000255119900076
AU  - Fisher,
AU  - H.
AU  - Gardner,
AU  - F.
AU  - E.
AU  - M.
AU  - Montgomery,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD007008.pub2
J2  - Cochrane Database Syst Rev.
KW  - RESISTANCE EDUCATION SYSTEMATIC REVIEWS CLINICAL-TRIALS TRAINING GREAT BIAS METAANALYSIS MEMBERSHIP PROGRAMS OFFENDERS QUALITY Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 290JU Times Cited: 2 Cited Reference Count: 70 Fisher, H. Gardner, F. E. M. Montgomery, P. 2 JOHN WILEY &amp; SONS LTD CHICHESTER COCHRANE DB SYST REV
PY  - 2008
SP  - 21
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive-behavioural interventions for preventing youth gang involvement for children and young people (7-16)
UR  - &lt;Go to ISI&gt;://WOS:000255119900076http://onlinelibrary.wiley.com/store/10.1002/14651858.CD007008.pub2/asset/CD007008.pdf?v=1&amp;t=ib7tda1i&amp;s=87b11bf3613ad18132d93da1884266ab2153d290
ER  -
TY  - JOUR
AB  - Triple P is a parenting program intended to prevent and to provide treatment for severe behavioral, emotional, and developmental problems in children. The aim of this meta-analysis was to assess the effectiveness of Triple P Level 4 interventions on parenting styles and parental competency. Level 4 is an intensive training program of 8-10 sessions for parents of children with more severe behavioral difficulties. The results indicated that the Triple P Level 4 interventions reduced dysfunctional parenting styles in parents and also improved parental competency. These effects were maintained well through time and appear to support the widespread adoption and implementation of Triple P Level 4 interventions that is taking place in an increasing number of countries around the world. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - de Graaf, Ireen: igraaf@Trimbos.nl; Speetjens, Paula: pspeetjens@tirmbos.nl; Smit, Filip: fsmit@Trimbos.nl; de Wolff, Marianne: marianne.dewolff@tno.nl; Tavecchio, Louis: L.W.C.Tavecchio@uva.nl de Graaf, Ireen: Trimbos Institute, Netherlands Institute for Mental Health and Addiction, P.O. Box 725, Utrecht, Netherlands, 3500 AS, igraaf@Trimbos.nl de Graaf, Ireen: Trimbos Institute, Netherlands Institute for Mental Health and Addiction, Utrecht, Netherlands Speetjens, Paula: Trimbos Institute, Netherlands Institute for Mental Health and Addiction, Utrecht, Netherlands Smit, Filip: Trimbos Institute, Netherlands Institute for Mental Health and Addiction, Utrecht, Netherlands de Wolff, Marianne: TNO Quality of Life, Leiden, Netherlands Tavecchio, Louis: University of Amsterdam, Amsterdam, Netherlands
AN  - 2008-16896-002
AU  - de
AU  - Graaf,
AU  - I.
AU  - Speetjens,
AU  - P.
AU  - Smit,
AU  - F.
AU  - de
AU  - Wolff,
AU  - M.
AU  - Tavecchio,
AU  - L.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0145445508317134
DP  - Ovid Technologies
KW  - parenting program, parenting styles, parental competency, Triple P, severe behavioral difficulties, children *Behavior Problems *Competence *Parent Training *Parental Characteristics *Parenting Style Childrearing Practices Severity (Disorders) Group &amp; F
LA  - English
M3  - Meta Analysis
PY  - 2008
SP  - 553-566
T2  - Family Relations: An Interdisciplinary Journal of Applied Family Studies
TI  - Effectiveness of the Triple P Positive Parenting Program on parenting: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc6&amp;AN=2008-16896-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1111%2Fj.1741-3729.2008.00522.x&amp;issn=0197-6664&amp;isbn=&amp;volume=57&amp;issue=5&amp;spage=553&amp;pages=553-566&amp;date=2008&amp;title=Family+Relations%3A+An+Interdisciplinary+Journal+of+Applied+Family+Studies&amp;atitle=Effectiveness+of+the+Triple+P+Positive+Parenting+Program+on+parenting%3A+A+meta-analysis.&amp;aulast=de+Graaf&amp;pid=%3Cauthor%3Ede+Graaf%2C+Ireen%3C%2Fauthor%3E%3CAN%3E2008-16896-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1741-3729.2008.00522.x/asset/j.1741-3729.2008.00522.x.pdf?v=1&amp;t=ib7wfc6y&amp;s=d090b3f0ac9714e664b16b683e90ea9c34542e22
VL  - 57
ER  -
TY  - JOUR
AB  - **Objective: **
To assess the effects of population tobacco control interventions on social inequalities in smoking.

**Data sources: **
Medical, nursing, psychological, social science and grey literature databases, bibliographies, hand-searches and contact with authors. 

**Study selection: **
Studies were included (n = 84) if they reported the effects of any population-level tobacco control intervention on smoking behaviour or attitudes in individuals or groups with different demographic or socioeconomic characteristics.

**Data extraction: **
Data extraction and quality assessment for each study were conducted by one reviewer and checked by a second. 

**Data synthesis: **
Data were synthesised using graphical (&quot;harvest plot&#039;&#039;) and narrative methods. No strong evidence of differential effects was found for smoking restrictions in workplaces and public places, although those in higher occupational groups may be more likely to change their attitudes or behaviour. Smoking restrictions in schools may be more effective in girls. Restrictions on sales to minors may be more effective in girls and younger children. Increasing the price of tobacco products may be more effective in reducing smoking among lower-income adults and those in manual occupations, although there was also some evidence to suggest that adults with higher levels of education may be more price-sensitive. Young people aged under 25 are also affected by price increases, with some evidence that boys and non-white young people may be more sensitive to price. 

**Conclusions: **
Population-level tobacco control interventions have the potential to benefit more disadvantaged groups and thereby contribute to reducing health inequalities.
AD  - [Thomas, S.; Ogilvie, D.] MRC, Social &amp; Publ Hlth Sci Unit, Glasgow G12 8RZ, Lanark, Scotland. [Fayter, D.; Misso, K.; Sowden, A.; Worthy, G.] Univ York, Ctr Reviews &amp; Disseminat, York YO10 5DD, N Yorkshire, England. [Petticrew, M.] Univ London London Sch Hyg &amp; Trop Med, PEHRU, London WC1E 7HT, England. [Whitehead, M.] Univ Liverpool, Div Publ Hlth, Liverpool L69 3GB, Merseyside, England. [Ogilvie, D.] MRC, Epidemiol Unit, Cambridge CB2 0QQ, England. Thomas, S (reprint author), MRC, Social &amp; Publ Hlth Sci Unit, Glasgow G12 8RZ, Lanark, Scotland. sian.thomas@btinternet.com
AN  - WOS:000257885500012
AU  - Thomas,
AU  - S.
AU  - Fayter,
AU  - D.
AU  - Misso,
AU  - K.
AU  - Ogilvie,
AU  - D.
AU  - Petticrew,
AU  - M.
AU  - Sowden,
AU  - A.
AU  - Whitehead,
AU  - M.
AU  - Worthy,
AU  - G.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1136/tc.2007.023911
J2  - Tob. Control
KW  - CIGARETTE-SMOKING CONTROL POLICIES PUBLIC-POLICY REDUCE SMOKING HEALTH INEQUALITIES ADOLESCENT SMOKING WARNING LABELS YOUTH SMOKING EVER-SMOKING YOUNG-ADULTS Public, Environmental &amp; Occupational Health
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 329QR Times Cited: 96 Cited Reference Count: 109 Thomas, S. Fayter, D. Misso, K. Ogilvie, D. Petticrew, M. Sowden, A. Whitehead, M. Worthy, G. Ogilvie, David/B-2444-2012 96 BMJ PUBLISHING GROUP LONDON TOB CONTROL
PY  - 2008
SP  - 8
T2  - Tobacco Control
TI  - Population tobacco control interventions and their effects on social inequalities in smoking: systematic review
UR  - &lt;Go to ISI&gt;://WOS:000257885500012http://tobaccocontrol.bmj.com/content/17/4/230.full.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - Based on evidence that early antisocial behavior is a key risk factor for continued delinquency and crime throughout the life course, early family/parent training, among its many functions, has been advanced as an important intervention/prevention effort. The prevention of behavior problems is one of the many objectives of early family/parent training, and it comprises the main focus of this review. Results of this review indicate that early family/parent training is an effective intervention for reducing behavior problems among young children and the weighted effect size was 0.35 approximately corresponding to 50% recidivism in the control group compared with 33% recidivism in the experimental group. The results from a series of analog to the ANOVA and weighted least squares regression models (with random effects) demonstrated that there were significant differences in the effect sizes of studies conducted in the US versus those conducted in other countries and that studies that were based on samples smaller than 100 children had larger effect sizes. Sample size was also the strongest predictor of the variation in the effect sizes. Additional descriptive evidence indicated that early family/parent training was also effective in reducing delinquency and crime in later adolescence and adulthood. Overall, the findings lend support for the continued use of early family/parent training to prevent behavior problems such as antisocial behavior and delinquency. Future research should be designed to test the main theories of the effects of early family/parent training, more explicitly including a better articulation of the causal mechanisms by which early family/parent training reduces delinquency and crime, and future early family/parent training program evaluations should employ high quality evaluation designs with longterm follow-ups, including repeated measures of antisocial behavior, delinquency, and crime over the life course.
AU  - Piquero,
AU  - A.
AU  - R.
AU  - Farrington,
AU  - D.
AU  - Jennings,
AU  - W.
AU  - G.
AU  - Tremblay,
AU  - R.
AU  - Welsh,
AU  - B.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2008.11
KW  - Antisocial behaviour
KW  - Parents
KW  - Parent education
KW  - Parent-child relationship
KW  - Crime
KW  - Juvenile delinquency
PY  - 2008
T2  - Campbell Systematic Reviews
TI  - Effects of Early Family/Parent Training Programs on Antisocial Behavior and Delinquency: A Systematic Review
ER  -
TY  - JOUR
AB  - **Background:** 
Many members of the public have negative attitudes towards antidepressants. Psychological interventions are more acceptable but require considerable therapist training. Acceptable psychological interventions that require less training and skill are needed to ensure increased uptake of intervention. A potential intervention of this sort is relaxation techniques.

**Objectives:** 
To determine whether relaxation techniques reduce depressive symptoms and improve response/remission.Search methods: The register of trials kept by the Cochrane Collaboration Depression, Anxiety and Neurosis Group was searched up to February 2008. We also searched the reference lists of included studies.

**Selection criteria:** 
Studies were included if they were randomised or quasi-randomised controlled trials of relaxation techniques (progressive muscle relaxation, relaxation imagery, autogenic training) in participants diagnosed with depression or having a high level of depression symptoms. Self-rated and clinician-rated depression scores and response/remission were the primary outcomes.

**Data collection and analysis:** 
Two reviewers selected the trials, assessed the quality and extracted trial and outcome data, with discrepancies resolved by consultation with a third. Trial authors were approached for missing data where possible and missing data were estimated or imputed in some cases. Continuous measures were summarised using standardised mean differences and dichotomous outcomes by risk ratios.

**Main results:** 
There were 15 trials with 11 included in the meta-analysis. Five trials showed relaxation reduced self-reported depression compared to wait-list, no treatment, or minimal treatment post intervention (SMD -0.59 (95% CI -0.94 to -0.24)). For clinician-rated depression, two trials showed a non-significant difference in the same direction (SMD -1.35 (95% CI -3.06 to 0.37)).Nine trials showed relaxation produced less effect than psychological (mainly cognitive-behavioural) treatment on self-reported depression (SMD = 0.38 (95% CI 0.14 to 0.62)). Three trials showed no significant difference between relaxation and psychological treatment on clinician-rated depression at post intervention (SMD 0.29 (95% CI -0.18 to 0.75)).Inconsistent effects were found when comparing relaxation training to medication and there were few data available comparing relaxation with complementary and lifestyle treatments.

**Authors&#039; conclusions:** 
Relaxation techniques were more effective at reducing self-rated depressive symptoms than no or minimal treatment. However, they were not as effective as psychological treatment. Data on clinician-rated depressive symptoms were less conclusive. Further research is required to investigate the possibility of relaxation being used as a first-line treatment in a stepped care approach to managing depression, especially in younger populations and populations with subthreshold or first episodes of depression.
AN  - CD007142
AU  - Jorm,
AU  - A.
AU  - F.
AU  - Morgan,
AU  - A.
AU  - J.
AU  - Hetrick,
AU  - S.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007142
KW  - Relaxation Therapy
KW  - Depression [therapy]
KW  - Mood Disorders [therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Humans[checkword]
KW  - Depressn
PY  - 2008
T2  - Cochrane Database of Systematic Reviews
TI  - Relaxation for depression
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007142.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007142.pub2/asset/CD007142.pdf?v=1&amp;t=iw7kyvqb&amp;s=c0e66a4df625218cf598b383fa0a207ad383b21a
ER  -
TY  - JOUR
AB  - **Background: **
uch controversy exists regarding the clinical efficacy of behavioural and developmental interventions for improving the core symptoms of autism spectrum disorders (ASD). We conducted a systematic review to summarize the evidence on the effectiveness of behavioural and developmental interventions for ASD. 

**Methods and Findings:** 
Comprehensive searches were conducted in 22 electronic databases through May 2007. Further information was obtained through hand searching journals, searching reference lists, databases of theses and dissertations, and contacting experts in the field. Experimental and observational analytic studies were included if they were written in English and reported the efficacy of any behavioural or developmental intervention for individuals with ASD. Two independent reviewers made the final study selection, extracted data, and reached consensus on study quality. Results were summarized descriptively and, where possible, meta-analyses of the study results were conducted. One-hundred-and-one studies at predominantly high risk of bias that reported inconsistent results across various interventions were included in the review. Meta-analyses of three controlled clinical trials showed that Lovaas treatment was superior to special education on measures of adaptive behaviour, communication and interaction, comprehensive language, daily living skills, expressive language, overall intellectual functioning and socialization. High-intensity Lovaas was superior to low-intensity Lovaas on measures of intellectual functioning in two retrospective cohort studies. Pooling the results of two randomized controlled trials favoured developmental approaches based on initiative interaction compared to contingency interaction in the amount of time spent in stereotyped behaviours and distal social behaviour, but the effect sizes were not clinically significant. No statistically significant differences were found for: Lovaas versus special education for non-verbal intellectual functioning; Lovaas versus Developmental Individual-difference relationship-based intervention for communication skills; computer assisted instruction versus no treatment for facial expression recognition; and TEACCH versus standard care for imitation skills and eye-hand integration. 

**Conclusions: **
While this review suggests that Lovaas may improve some core symptoms of ASD compared to special education, these findings are based on pooling of a few, methodologically weak studies with few participants and relatively short-term follow-up. As no definitive behavioural or developmental intervention improves all symptoms for all individuals with ASD, it is recommended that clinical management be guided by individual needs and availability of resources.
AD  - [Ospina, Maria B.; Seida, Jennifer Krebs; Karkhaneh, Mohammad; Hartling, Lisa; Tjosvold, Lisa; Vandermeer, Ben] Univ Alberta, Alberta Res Ctr Hlth Evidence, Edmonton, AB, Canada. [Clark, Brenda] Univ Alberta, Fac Med &amp; Dent, Dept Pediat, Edmonton, AB T6G 2M7, Canada. [Smith, Veronica] Univ Alberta, Fac Ed, Dept Ed Psychol, Edmonton, AB T6G 2M7, Canada. Ospina, MB (reprint author), Univ Alberta, Alberta Res Ctr Hlth Evidence, Edmonton, AB, Canada. veronica.smith@ualberta.ca
AN  - WOS:000265448400011
AU  - Ospina,
AU  - M.
AU  - B.
AU  - Seida,
AU  - J.
AU  - K.
AU  - Clark,
AU  - B.
AU  - Karkhaneh,
AU  - M.
AU  - Hartling,
AU  - L.
AU  - Tjosvold,
AU  - L.
AU  - Vandermeer,
AU  - B.
AU  - Smith,
AU  - V.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1371/journal.pone.0003755
J2  - PLoS One
KW  - RANDOMIZED CONTROLLED-TRIAL HIGH-FUNCTIONING AUTISM ASPERGER-SYNDROME YOUNG-CHILDREN PRESCHOOL-CHILDREN MENTAL-RETARDATION COMMUNICATION INTERVENTIONS METHODOLOGICAL QUALITY TRAINING-PROGRAM SOCIAL BEHAVIORS Multidisciplinary Sciences
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 436XC Times Cited: 62 Cited Reference Count: 174 Ospina, Maria B. Seida, Jennifer Krebs Clark, Brenda Karkhaneh, Mohammad Hartling, Lisa Tjosvold, Lisa Vandermeer, Ben Smith, Veronica Alberta Centre for Child, Family and Community Research [G299000474] This study was funded by the Grant # G299000474 from the Alberta Centre for Child, Family and Community Research. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Alberta Centre for Child, Family and Community Research. 63 PUBLIC LIBRARY SCIENCE SAN FRANCISCO PLOS ONE
PY  - 2008
SP  - 32
T2  - Plos One
TI  - Behavioural and Developmental Interventions for Autism Spectrum Disorder: A Clinical Systematic Review
UR  - &lt;Go to ISI&gt;://WOS:000265448400011http://www.plosone.org/article/fetchObject.action?uri=info:doi/10.1371/journal.pone.0003755&amp;representation=PDF
VL  - 3
ER  -
TY  - JOUR
AB  - A meta-analysis was conducted to examine the effects of exercise on anxiety. Because previous meta-analyses in the area included studies of varying quality, only randomized, controlled trials were included in the present analysis. 

Results from 49 studies show an overall effect size of -0.48, indicating larger reductions in anxiety among exercise groups than no-treatment control groups. 

Exercise groups also showed greater reductions in anxiety compared with groups that received other forms of anxiety-reducing treatment (effect size = -0.19). 

Because only randomized, controlled trials were examined, these results provide Level 1, Grade A evidence for using exercise in the treatment of anxiety. 

In addition, exercise dose data were calculated to examine the relationship between dose of exercise and the corresponding magnitude of effect size.
AD  - Wipfli,Bradley M. Department of Kinesiology, Arizona State University, Tempe, AZ, USA.
AN  - 18723899
AU  - Wipfli,
AU  - B.
AU  - M.
AU  - Rethorst,
AU  - C.
AU  - D.
AU  - Landers,
AU  - D.
AU  - M.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Har ikke DOI: https://www.ncbi.nlm.nih.gov/pubmed/18723899
DP  - Ovid Technologies
J2  - J Sport Exerc Psychol
KW  - Adolescent Adult Aged Aged, 80 and over *Anxiety/th [Therapy] *Exercise/px [Psychology] Female Humans Male Middle Aged Randomized Controlled Trials as Topic
LA  - English
M3  - Meta-Analysis
N1  - Wipfli, Bradley M Rethorst, Chad D Landers, Daniel M
PY  - 2008
SP  - 392-410
T2  - Journal of Sport and Exercise Psychology
TI  - The anxiolytic effects of exercise: a meta-analysis of randomized trials and dose-response analysis.[Erratum appears in J Sport Exerc Psychol. 2009 Feb;31(1):128-9]
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18723899 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18723899&amp;id=doi:&amp;issn=0895-2779&amp;isbn=&amp;volume=30&amp;issue=4&amp;spage=392&amp;pages=392-410&amp;date=2008&amp;title=Journal+of+Sport+%26+Exercise+Psychology&amp;atitle=The+anxiolytic+effects+of+exercise%3A+a+meta-analysis+of+randomized+trials+and+dose-response+analysis.&amp;aulast=Wipfli&amp;pid=%3Cauthor%3EWipfli+BM%3C%2Fauthor%3E%3CAN%3E18723899%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 30
ER  -
TY  - JOUR
AB  - **Background:** 
Youth gangs have long been studied in the United States and interest elsewhere is increasing. Many studies document a robust and consistent relationship between gang membership and elevated delinquency. One theory of gang involvement, drawing on anomie and strain theories, proposes that the gang provides a means of fulfilling the economic needs of youth excluded from legitimate labour markets. Opportunities provision is a gang prevention strategy based on this theory and the principle that providing youth with educational and employment opportunities may reduce gang involvement. Common techniques within opportunities provision include tutoring, remedial education, job training, and job placement.

**Objectives:** 
To determine the effectiveness of opportunities provision for preventing youth gang involvement for children and young people aged 7 to 16.

**Search methods:** 
Electronic searches were conducted of the Cochrane Library, MEDLINE, ASSIA, CINAHL, CJA, Dissertations Abstracts, EMBASE, ERIC, IBSS, LILACs, LexisNexis Butterworths, NCJR Service Abstracts Database, PsycINFO, and Sociological Abstracts, to April 2007. Reviewers contacted relevant organisations, individuals and list-servs and searched pertinent websites and reference lists.

**Selection criteria:** 
All randomised controlled trials or quasi-randomised controlled trials of interventions that have opportunities provision as the majority component, delivered to children and youths aged 7 to 16 not involved in a gang, compared to any other or no intervention.

**Data collection and analysis:**
Searches yielded 2,696 unduplicated citations. 2,676 were excluded based on title and abstract. Two were excluded based on personal communication with study authors. Full-text reports for 18 citations were retrieved. 16 were excluded because they were not evaluations, did not address a gang prevention programme, did not include gang-related outcomes, did not include opportunities provision intervention components, or presented preliminary findings for outcomes reported in another citation. The remaining two reports were at least partially relevant to opportunities provision for gang prevention, but methodological flaws excluded both from analysis.

**Main results:** 
No randomised controlled trials or quasi-randomised controlled trials were identified.

**Authors&#039; conclusions:** 
No evidence from randomised controlled trials or quasi-randomised controlled trials currently exists regarding the effectiveness of opportunities provision for gang prevention. Only two studies addressed opportunities provision as a gang prevention strategy, a case study and a qualitative study, both of which had such substantial methodological limitations that even speculative conclusions as to the impact of opportunities provision were impossible. Rigorous primary evaluations of gang prevention strategies are crucial to develop this research field, justify funding of existing interventions, and guide future gang prevention programmes and policies.
AN  - CD007002
AU  - Fisher,
AU  - H.
AU  - Montgomery,
AU  - P.
AU  - Gardner,
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd007002.pub2
KW  - Peer Group
KW  - Crime [prevention &amp; control]
KW  - Juvenile Delinquency [prevention &amp; control]
KW  - Social Alienation
KW  - Social Identification
KW  - Vocational Education
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
PY  - 2008
T2  - Cochrane Database of Systematic Reviews
TI  - Opportunities provision for preventing youth gang involvement for children and young people (7-16)
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD007002.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD007002.pub2/asset/CD007002.pdf?v=1&amp;t=iw7kfitm&amp;s=c097a62f76bf6c5a915785900c57c61cfa1f837f
ER  -
TY  - JOUR
AB  - **OBJECTIVES:**
To evaluate the long-term effectiveness of recent behavioural interventions in the prevention of cigarette use among children and youth and to compare the effectiveness of different school-based, community-based and multisectorial intervention strategies. 

**METHODS: **
A structured search of databases and a manual search of reference lists was conducted. Randomised controlled trials published in English or German between August 2001 and August 2006 targeting youths up to 18 years of age were assessed independently by two researchers according to predefined inclusion criteria and with regard to methodological quality. Data abstraction was performed and crosschecked by two researchers. Where appropriate, pooled effect estimates were calculated and tested in sensitivity analyses. 

**RESULTS: **
Of 3555 articles, 35 studies met the inclusion criteria. The follow-up duration ranged from 12 months to 120 months. Although the overall effectiveness of prevention programs showed considerable heterogeneity, the majority of studies reported some positive long-term effects for behavioural smoking prevention programs. There was evidence that community-based and multisectorial interventions were effective in reducing smoking rates; in contrast, the evidence for school-based programs alone was inconclusive. Regardless of the type of intervention, the reductions observed in smoking rates were only modest. 

**CONCLUSIONS:** 
The present work identified moderate evidence for the effectiveness of behavioural interventions to prevent smoking. Although evidence for the effectiveness of school-based interventions was inconclusive, evidence for the effectiveness of community-based and multisectorial interventions was somewhat stronger. Future research should investigate the effectiveness of specific intervention components and the cost-effectiveness of interventions analysed in methodologically high-quality studies.
AD  - Muller-Riemenschneider,F. Institute for Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, 10098 Berlin, Germany. falk.mueller-riemenschneider@charite.de
AN  - 18522963
AU  - Muller-Riemenschneider,
AU  - F.
AU  - Bockelbrink,
AU  - A.
AU  - Reinhold,
AU  - T.
AU  - Rasch,
AU  - A.
AU  - Greiner,
AU  - W.
AU  - Willich,
AU  - S.
AU  - N.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/tc.2007.024281
DP  - Ovid Technologies
J2  - Tob Control
KW  - Adolescent *Behavior Therapy/og [Organization &amp; Administration] Child Community Health Services/og [Organization &amp; Administration] Health Promotion/og [Organization &amp; Administration] Humans Program Evaluation School Health Services/og [Organization &amp; Ad
L1  - internal-pdf://1347908023/Muller-Riemensc-2008-Long-term effectiveness o.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Muller-Riemenschneider, F Bockelbrink, A Reinhold, T Rasch, A Greiner, W Willich, S N
PY  - 2008
SP  - 301-2
T2  - Tobacco Control
TI  - Long-term effectiveness of behavioural interventions to prevent smoking among children and youth
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18522963 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18522963&amp;id=doi:10.1136%2Ftc.2007.024281&amp;issn=0964-4563&amp;isbn=&amp;volume=17&amp;issue=5&amp;spage=301&amp;pages=301-2&amp;date=2008&amp;title=Tobacco+Control&amp;atitle=Long-term+effectiveness+of+behavioural+interventions+to+prevent+smoking+among+children+and+youth.&amp;aulast=Muller-Riemenschneider&amp;pid=%3Cauthor%3EMuller-Riemenschneider+F%3C%2Fauthor%3E%3CAN%3E18522963%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://tobaccocontrol.bmj.com/content/17/5/301.full.pdf
UR  - http://tobaccocontrol.bmj.com/content/tobaccocontrol/17/5/301.full.pdf
VL  - 17
ER  -
TY  - JOUR
AB  - A meta-analysis encompassing all studies evaluating the impact of the Triple P-Positive Parenting Program on parent and child outcome measures was conducted in an effort to identify variables that moderate the program&#039;s effectiveness. 

Hierarchical linear models (HLM) with three levels of data were employed to analyze effect sizes. 

The results (N=55 studies) indicate that Triple P causes positive changes in parenting skills, child problem behavior and parental well-being in the small to moderate range, varying as a function of the intensity of the intervention. 

The most salient findings of variables moderating the interventions&#039; impact were larger effects found on parent report as compared to observational measures and more improvement associated with more intensive formats and initially more distressed families. 

Sample characteristics (e.g., child&#039;s age, being a boy) and methodological features (e.g., study quality) exhibited different degrees of predictive power. 

The analysis clearly identified several strengths of the Triple P system, most importantly its ability to effect meaningful improvement in parents and children. 

Some limitations pertain to the small evidence-base of certain formats of Triple P and the lack of follow-up data beyond 3 years after the intervention. 

Many of the present findings may be relevant to other evidence-based parenting programs.
AD  - Nowak,Christoph. Institute of Psychology, University of Braunschweig, Humboldtstr. 33, 38106 Braunschweig, Germany. nowakchr@googlemail.com
AN  - 18509758
AU  - Nowak,
AU  - C.
AU  - Heinrichs,
AU  - N.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10567-008-0033-0
DP  - Ovid Technologies
J2  - Clin Child Fam Psychol Rev
KW  - Adult Child Humans *Models, Psychological *Parent-Child Relations *Parenting *Program Development
LA  - English
M3  - Meta-Analysis
N1  - Nowak, Christoph Heinrichs, Nina
PY  - 2008
SP  - 114-44
T2  - Clinical Child and Family Psychology Review
TI  - A comprehensive meta-analysis of Triple P-Positive Parenting Program using hierarchical linear modeling: effectiveness and moderating variables
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18509758 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18509758&amp;id=doi:10.1007%2Fs10567-008-0033-0&amp;issn=1096-4037&amp;isbn=&amp;volume=11&amp;issue=3&amp;spage=114&amp;pages=114-44&amp;date=2008&amp;title=Clinical+Child+%26+Family+Psychology+Review&amp;atitle=A+comprehensive+meta-analysis+of+Triple+P-Positive+Parenting+Program+using+hierarchical+linear+modeling%3A+effectiveness+and+moderating+variables.&amp;aulast=Nowak&amp;pid=%3Cauthor%3ENowak+C%3C%2Fauthor%3E%3CAN%3E18509758%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10567-008-0033-0
UR  - https://link.springer.com/article/10.1007%2Fs10567-008-0033-0
VL  - 11
ER  -
TY  - JOUR
AB  - The evidence-base of psychosocial treatment outcome studies for depressed youth conducted since 1998 is examined. 

All studies for depressed children meet Nathan and Gorman&#039;s (2002) criteria for Type 2 studies whereas the adolescent protocols meet criteria for both Type 1 and Type 2 studies. 

Based on the Task Force on the Promotion and Dissemination of Psychological Procedures guidelines, the cognitive-behavioral therapy (CBT) based specific programs of Penn Prevention Program, Self-Control Therapy, and Coping with Depression-Adolescent are probably efficacious. 

Interpersonal Therapy-Adolescent, which falls under the theoretical category of interpersonal therapy (IPT), also is a probably efficacious treatment. 

CBT provided through the modalities of child group only and child group plus parent components are well-established intervention approaches for depressed children. 

For adolescents, two modalities are well-established (CBT adolescent only group, IPT individual), and three are probably efficacious (CBT adolescent group plus parent component, CBT individual, CBT individual plus parent/family component). 

From the broad theoretical level, CBT has well-established efficacy and behavior therapy meets criteria for a probably efficacious intervention for childhood depression. 

For adolescent depression, both CBT and IPT have well-established efficacy. Future research directions and best practices are offered. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - David-Ferdon, Corinne: cferdon@cdc.gov David-Ferdon, Corinne: Centers for Disease Control and Prevention, National Center for Injury Prevention and Control, 4770 Buford Highway NE, MS-F64, Atlanta, GA, US, 30341, cferdon@cdc.gov David-Ferdon, Corinne: Emory University School of Medicine, Atlanta, GA, US Kaslow, Nadine J.: Emory University School of Medicine, Atlanta, GA, US
AN  - 2008-04804-004
AU  - Ferdon,
AU  - C.
AU  - D.
AU  - Kaslow,
AU  - N.
AU  - J.
DA  - Jan-Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/15374410701817865
DP  - Ovid Technologies
KW  - evidence based psychosocial treatments, children, adolescent, depression, interpersonal therapy, cognitive-behavioral therapy *Cognitive Behavior Therapy *Evidence Based Practice *Interpersonal Psychotherapy *Major Depression *Pediatrics Psychosocial Fa
LA  - English
M3  - Literature Review
N1  - Special Issue: Evidence-based psychosocial treatments for children and adolescents: A ten year update
PY  - 2008
SP  - 62-104
T2  - Journal of Clinical Child and Adolescent Psychology
TI  - Evidence-based psychosocial treatments for child and adolescent depression
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc6&amp;AN=2008-04804-004 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F15374410701817865&amp;issn=1537-4416&amp;isbn=&amp;volume=37&amp;issue=1&amp;spage=62&amp;pages=62-104&amp;date=2008&amp;title=Journal+of+Clinical+Child+and+Adolescent+Psychology&amp;atitle=Evidence-based+psychosocial+treatments+for+child+and+adolescent+depression.&amp;aulast=David-Ferdon&amp;pid=%3Cauthor%3EDavid-Ferdon%2C+Corinne%3C%2Fauthor%3E%3CAN%3E2008-04804-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/15374410701817865
VL  - 37
ER  -
TY  - JOUR
AB  - **Aims: **
In order to quantify the effectiveness of family interventions in reducing adolescent drinking, we conducted a theta-analysis of randomized controlled trials. 

**Methods: **
We searched the Cochrane Database of Systematic Reviews, ERIC (Educational Research Information Center), Medline and PsycInfo for studies published between 1995 and September 2006. Summary estimates (OR and Cohen&#039;s d) were derived from the difference in changed alcohol consumption between family intervention and control group. Random effect models were used to estimate the overall effect and heterogeneity anion; studies. Eighteen papers describing nine independent trials were eligible for inclusion in this meta-analysis.

**Results: **
The overall effect of family interventions in reducing alcohol initiation (OR: 0.71; 95% CI: 0.54, 0.94) and frequency of alcohol use (d: -0.25: 95%r CI: -0.37. -0.12) show the success of these programs. There was heterogeneity between studies reporting on alcohol initiation (p-heterogeneity: &lt; 0.001: I-2 : 78.6%). Yet, the most successful interventions continued to be effective in reducing alcohol initiation even at 48 months follow-up (pooled estimate (OR): 0.53; 95% CI: 0.38, 0.75). 

**Conclusion: **
The results from this meta-analysis suggest that the overall effect of family interventions on adolescent alcohol use is small, yet consistent and effective even at 48 months. 

(c) 2008 Elsevier Ireland Ltd. All rights reserved.
AD  - [Smit, Evelien; Verdurmen, Jacqueline; Monshouwer, Karin; Smit, Filip] Trimbos Inst, Netherlands Inst Mental Hlth &amp; Addict, NL-3500 AS Utrecht, Netherlands. Smit, E (reprint author), Trimbos Inst, Netherlands Inst Mental Hlth &amp; Addict, POB 725, NL-3500 AS Utrecht, Netherlands. esmit@trimbos.nl
AN  - WOS:000259560600001
AU  - Smit,
AU  - E.
AU  - Verdurmen,
AU  - J.
AU  - Monshouwer,
AU  - K.
AU  - Smit,
AU  - F.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.drugalcdep.2008.03.032
J2  - Drug Alcohol Depend.
KW  - meta-analysis randomized controlled trial alcohol consumption adolescent family intervention FOCUSED PREVENTIVE INTERVENTIONS SUBSTANCE USE DRINKING BEHAVIOR INITIATION OUTCOMES UNIVERSAL FAMILY RISK-FACTOR PROGRAM HEALTH AGE PARENT Substance Abuse Psyc
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 353IT Times Cited: 49 Cited Reference Count: 51 Smit, Evelien Verdurmen, Jacqueline Monshouwer, Karin Smit, Filip The Dutch Ministry of Health, Welfare and Sport The Dutch Ministry of Health, Welfare and Sport supported this research financially. 50 ELSEVIER IRELAND LTD CLARE DRUG ALCOHOL DEPEN
PY  - 2008
SP  - 195-206
T2  - Drug and Alcohol Dependence
TI  - Family interventions and their effect on adolescent alcohol use in general populations; a meta-analysis of randomized controlled trials
UR  - &lt;Go to ISI&gt;://WOS:000259560600001http://ac.els-cdn.com/S0376871608001270/1-s2.0-S0376871608001270-main.pdf?_tid=ffb59216-18d9-11e5-b360-00000aacb361&amp;acdnat=1434976208_9564f24a8c0962691065ecbb37325396
VL  - 97
ER  -
TY  - JOUR
AB  - Suicide behavior is a serious clinical problem worldwide, and understanding ways of reducing it is a priority. 

A systematic review and meta-analysis were carried out to investigate whether Cognitive-behavioral therapies (CBTs) would reduce suicide behavior. From 123 potential articles, 28 studies met the entry criteria. 

Overall, there was a highly significant effect for CBT in reducing suicide behavior. Subgroup analysis indicates a significant treatment effect for adult samples (but not adolescent), for individual treatments (but not group), and for CBT when compared to minimal treatment or treatment as usual (but not when compared to another active treatment). 

There was evidence for treatment effects, albeit reduced, over the medium term. 

Although these results appear optimistic in advocating the use of CBT in ameliorating suicidal thoughts, plans, and behaviors, evidence of a publication bias tempers such optimism.
AD  - [Tarrier, Nicholas] Univ Manchester, Sch Psychol Sci, Div Clin Psychol, Manchester M13 9PL, Lancs, England. [Tarrier, Nicholas] Natl Hlth Serv, Manchester Mental Hlth &amp; Social Care Trust, Manchester, Lancs, England. Tarrier, N (reprint author), Univ Manchester, Sch Psychol Sci, Div Clin Psychol, Zochonis Bldg,Oxford Rd, Manchester M13 9PL, Lancs, England. nicholas.tarrier@manchester.ac.uk
AN  - WOS:000261928800005
AU  - Tarrier,
AU  - N.
AU  - Taylor,
AU  - K.
AU  - Gooding,
AU  - P.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/0145445507304728
J2  - Behav. Modificat.
KW  - psychological therapy suicidal behavior CBT RANDOMIZED CONTROLLED-TRIAL BORDERLINE PERSONALITY-DISORDER DELIBERATE SELF-HARM CLINICAL-TRIALS SCHIZOPHRENIC-PATIENTS FOLLOW-UP THERAPY QUALITY PREVENTION ADOLESCENTS Psychology, Clinical
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 387CH Times Cited: 67 Cited Reference Count: 71 Tarrier, Nicholas Taylor, Katherine Gooding, Patricia 68 SAGE PUBLICATIONS INC THOUSAND OAKS BEHAV MODIF
PY  - 2008
SP  - 77-108
T2  - Behavior Modification
TI  - Cognitive-Behavioral Interventions to Reduce Suicide Behavior A Systematic Review and Meta-Analysis
UR  - &lt;Go to ISI&gt;://WOS:000261928800005http://bmo.sagepub.com/content/32/1/77http://bmo.sagepub.com/content/32/1/77.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/0145445507304728?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 32
ER  -
TY  - JOUR
AB  - This article reviews research on evidence-based treatments (EBTs) for ethnic minority youth using criteria from Chambless et al. (1998), Chambless et al. (1996), and Chambless and Hollon (1998). 

Although no well-established treatments were identified, probably efficacious or possibly efficacious treatments were found for ethnic minority youth with anxiety-related problems, attention-deficit/hyperactivity disorder, depression, conduct problems, substance use problems, trauma-related syndromes, and other clinical problems. In addition, all studies met either Nathan and Gorman&#039;s (2002) Type 1 or Type 2 methodological criteria. 

A brief meta-analysis showed overall treatment effects of medium magnitude (d = .44). Effects were larger when EBTs were compared to no treatment (d = .58) or psychological placebos (d = .51) versus treatment as usual (d = .22). Youth ethnicity (African American, Latino, mixed/other minority), problem type, clinical severity, diagnostic status, and culture-responsive treatment status did not moderate treatment outcome. 

Most studies had low statistical power and poor representation of less acculturated youth. Few tests of cultural adaptation effects have been conducted in the literature and culturally validated outcome measures are mostly lacking. 

Recommendations for clinical practice and future research directions are provided.
AD  - Huey,Stanley J Jr. University of Southern California, Los Angeles, CA 90089-1061, USA. hueyjr@usc.edu
AN  - 18444061
AU  - Huey,
AU  - S.
AU  - J.
AU  - Polo,
AU  - A.
AU  - J.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15374410701820174
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
KW  - Acculturation Adolescent African Continental Ancestry Group/px [Psychology] Child Cultural Competency *Ethnic Groups/px [Psychology] European Continental Ancestry Group/px [Psychology] *Evidence-Based Medicine Hispanic Americans/px [Psychology] Humans M
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural Research Support, U.S. Gov&#039;t, P.H.S. Review
N1  - Huey, Stanley J Jr Polo, Antonio J K08 MH069583 (United States NIMH NIH HHS) K08 MH069583-04 (United States NIMH NIH HHS) P01 HS1087 (United States AHRQ HHS)
PY  - 2008
SP  - 262-301
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Evidence-based psychosocial treatments for ethnic minority youth
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18444061
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18444061&amp;id=doi:10.1080%2F15374410701820174&amp;issn=1537-4416&amp;isbn=&amp;volume=37&amp;issue=1&amp;spage=262&amp;pages=262-301&amp;date=2008&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Evidence-based+psychosocial+treatments+for+ethnic+minority+youth.&amp;aulast=Huey+SJ&amp;pid=%3Cauthor%3EHuey+SJ+Jr%3C%2Fauthor%3E%3CAN%3E18444061%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/15374410701820174
VL  - 37
ER  -
TY  - JOUR
AB  - This meta-analysis evaluates the effect of hypnosis in reducing emotional distress associated with medical procedures. PsycINFO and PubMed were searched from their inception through February 2008. Randomized controlled trials of hypnosis interventions, administered in the context of clinical medical procedures, with a distress outcome, were included in the meta-analysis (26 of 61 papers initially reviewed). Information on sample size, study methodology, participant age and outcomes were abstracted independently by 2 authors using a standardized form. Disagreements were resolved by consensus. Effects from the 26 trials were based on 2342 participants. Results indicated an overall large effect size (ES) of 0.88 (95% CI = 0.57-1.19) in favour of hypnosis. Effect sizes differed significantly (p &lt; 0.01) according to age (children benefitted to a greater extent than adults) and method of hypnosis delivery, but did not differ based on the control condition used (standard care vs. attention control).
AN  - 19746190
AU  - Schnur,
AU  - J.
AU  - B.
AU  - Kafer,
AU  - I.
AU  - Marcus,
AU  - C.
AU  - Montgomery,
AU  - G.
AU  - H.
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - /10.1002/ch.364
L1  - internal-pdf://2666519215/Schnur-2008-Hypnosis to Manage Distress Relate.pdf
PY  - 2008
SP  - 114-128
T2  - Contemporary Hypnosis
TI  - Hypnosis to Manage Distress Related to Medical Procedures: A Meta-Analysis
UR  - https://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=pmnm&amp;AN=19746190
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739386/pdf/nihms92531.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - The article reviews psychosocial treatments for phobic and anxiety disorders in youth. Using criteria from Nathan and Gorman (2002), 32 studies are evaluated along a continuum of methodological rigor. 

In addition, the treatments evaluated in each of the 32 studies are classified according to Chambless et al.&#039;s (1996) and Chambless and Hollon&#039;s (1998) criteria. Findings from a series of meta-analyses of the studies that used waitlists also are reported. 

In accordance with Nathan and Gorman, the majority of the studies were either methodologically robust or fairly rigorous. In accordance with Chambless and colleagues, although no treatment was well-established, Individual Cognitive Behavior Therapy, Group Cognitive Behavior Therapy (GCBT), GCBT with Parents, GCBT for social phobia (SOP), and Social Effectiveness Training for children with SOP each met criteria for probably efficacious. 

The other treatments were either possibly efficacious or experimental. Meta-analytic results revealed no significant differences between individual and group treatments on diagnostic recovery rates and anxiety symptom reductions, as well as other youth symptoms (i.e., fear, depression, internalizing and externalizing problems). 

Parental involvement was similarly efficacious as parental noninvolvement in individual and group treatment formats. The article also provides a summary of the studies that have investigated mediators, moderators, and predictors of treatment outcome. 

The article concludes with a discussion of the clinical representativeness and generalizability of treatments, practice guidelines, and future research directions.
AD  - Silverman,Wendy K. Child and Family Psychosocial Research Center, Child Anxiety and Phobia Program, Department of Psychology, University Park, Florida International University, Miami, FL 33199, USA. silverw@fiu.edu
AN  - 18444055
AU  - Silverman,
AU  - W.
AU  - K.
AU  - Pina,
AU  - A.
AU  - A.
AU  - Viswesvaran,
AU  - C.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/15374410701817907.
DP  - Ovid Technologies
J2  - J Clin Child Adolesc Psychol
KW  - Adolescent Child Cognitive Therapy/mt [Methods] *Evidence-Based Medicine Family Therapy/mt [Methods] Humans Phobic Disorders/di [Diagnosis] *Phobic Disorders/th [Therapy] Practice Guidelines as Topic *Psychotherapy/mt [Methods] Psychotherapy, Group/mt [
LA  - English
M3  - Comparative Study Research Support, N.I.H., Extramural Review
N1  - Silverman, Wendy K Pina, Armando A Viswesvaran, Chockalingam R01 63997 (United States PHS HHS)
PY  - 2008
SP  - 105-30
T2  - Journal of Clinical Child &amp; Adolescent Psychology
TI  - Evidence-based psychosocial treatments for phobic and anxiety disorders in children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18444055
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18444055&amp;id=doi:10.1080%2F15374410701817907&amp;issn=1537-4416&amp;isbn=&amp;volume=37&amp;issue=1&amp;spage=105&amp;pages=105-30&amp;date=2008&amp;title=Journal+of+Clinical+Child+%26+Adolescent+Psychology&amp;atitle=Evidence-based+psychosocial+treatments+for+phobic+and+anxiety+disorders+in+children+and+adolescents.&amp;aulast=Silverman&amp;pid=%3Cauthor%3ESilverman+WK%3C%2Fauthor%3E%3CAN%3E18444055%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/15374410701817907
VL  - 37
ER  -
TY  - JOUR
AB  - This review synthesized findings from 17 studies since 1998 regarding evaluation of outpatient treatments for adolescent substance abuse. 
These studies represented systematic design advances in adolescent clinical trial science. The research examined 46 different intervention conditions with a total sample of 2,307 adolescents. The sample included 7 individual cognitive behavior therapy (CBT) replications (n = 367), 13 group CBT replications (n = 771), 17 family therapy replications (n = 850) and 9 minimal treatment control conditions (n = 319). 

The total sample was composed of approximately 75% males, and the ethnic/racial distribution was approximately 45% White, 25% Hispanic, 25% African American, and 5% other groups. Meta-analysis was used to evaluate within-group effect sizes as well as differences between active treatment conditions and the minimal treatment control conditions. Methodological rigor of studies was classified using Nathan and Gorman (2002) criteria, and treatments were classified using criteria for well-established and probably efficacious interventions based on Chambless et al. (1996). 

Three treatment approaches, multidimensional family therapy, functional family therapy, and group CBT emerged as well-established models for substance abuse treatment. 

However, a number of other models are probably efficacious, and none of the treatment approaches appeared to be clearly superior to any others in terms of treatment effectiveness for adolescent substance abuse.
AD  - [Waldron, Holly Barrett; Turner, Charles W.] Oregon Res Inst, Eugene, OR 97403 USA. Waldron, HB (reprint author), Oregon Res Inst, 1715 Franklin Blvd, Eugene, OR 97403 USA. holly@ori.orgM
AN  - WOS:000254916600010
AU  - Waldron,
AU  - H.
AU  - B.
AU  - Turner,
AU  - C.
AU  - W.
DA  - Jan-Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/15374410701820133
J2  - J. Clin. Child Adolesc. Psychol.
KW  - MULTIDIMENSIONAL FAMILY-THERAPY RANDOMIZED CLINICAL-TRIAL YOUTH TREATMENT CYT DRUG-ABUSERS PSYCHOTHERAPY-RESEARCH BEHAVIOR PROBLEMS FOLLOW-UP ANTISOCIAL PERSONALITY POSTTREATMENT OUTCOMES MULTISYSTEMIC THERAPY Psychology, Clinical Psychology, Developmen
L1  - internal-pdf://1131701534/Waldron-2008-Evidence-based psychosocial treat.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 287KS Times Cited: 124 Cited Reference Count: 167 Waldron, Holly Barrett Turner, Charles W. 125 LAWRENCE ERLBAUM ASSOC INC-TAYLOR &amp; FRANCIS PHILADELPHIA J CLIN CHILD ADOLESC
PY  - 2008
SP  - 238-261
T2  - Journal of Clinical Child and Adolescent Psychology
TI  - Evidence-based psychosocial treatments for adolescent substance abuse
UR  - &lt;Go to ISI&gt;://WOS:000254916600010http://www.tandfonline.com/doi/pdf/10.1080/15374410701820133
UR  - http://www.tandfonline.com/doi/pdf/10.1080/15374410701820133?needAccess=true
VL  - 37
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To conduct a meta-analysis on randomized, controlled treatment trials of pediatric obsessive-compulsive disorder (OCD). 

**METHOD:  **
Studies were included if they employed randomized, controlled methodology and treated young people (19 years or under) with OCD. A comprehensive literature search identified 13 RCTs containing 10 pharmacotherapy to control comparisons (N = 1016) and five cognitive-behavioral therapy (CBT) to control comparisons (N = 161).

**RESULTS:**
Random effects modeling yielded statistically significant pooled effect size (ES) estimates for pharmacotherapy (ES = .48, 95% CI = .36 to .61, p &lt; .00001) and CBT (ES = 1.45, 95% CI = .68 to 2.22, p = .002). The results were robust to publication bias. 

**CONCLUSIONS: **
This is the first meta-analysis of treatment RCTs for pediatric OCD. CBT and pharmacotherapy were the only treatments effective beyond control in alleviating OCD symptoms. CBT showed a greater ES than pharmacotherapy. Previous meta-analyses that included uncontrolled trials exaggerated the efficacy of both treatments.
AD  - Watson,Hunna J. Curtin University of Technology, Perth, Western Australia, Australia. h.watson@curtin.edu.au
AN  - 18400058
AU  - Watson,
AU  - H.
AU  - J.
AU  - Rees,
AU  - C.
AU  - S.
DA  - May
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1469-7610.2007.01875.x.
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
KW  - Adolescent Adult Child Cognitive Therapy Combined Modality Therapy Drug Therapy/mt [Methods] Humans Obsessive-Compulsive Disorder/dt [Drug Therapy] *Obsessive-Compulsive Disorder/th [Therapy] *Randomized Controlled Trials as Topic
LA  - English
M3  - Meta-Analysis
N1  - Watson, Hunna J Rees, Clare S Comment in: J Child Psychol Psychiatry. 2008 May;49(5):469-70; PMID: 18400057
PY  - 2008
SP  - 489-98
T2  - Journal of Child Psychology &amp; Psychiatry &amp; Allied Disciplines
TI  - Meta-analysis of randomized, controlled treatment trials for pediatric obsessive-compulsive disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18400058
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18400058&amp;id=doi:10.1111%2Fj.1469-7610.2007.01875.x&amp;issn=0021-9630&amp;isbn=&amp;volume=49&amp;issue=5&amp;spage=489&amp;pages=489-98&amp;date=2008&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Meta-analysis+of+randomized%2C+controlled+treatment+trials+for+pediatric+obsessive-compulsive+disorder.&amp;aulast=Watson&amp;pid=%3Cauthor%3EWatson+HJ%3C%2Fauthor%3E%3CAN%3E18400058%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1469-7610.2007.01875.x/asset/j.1469-7610.2007.01875.x.pdf?v=1&amp;t=ib3hhucr&amp;s=4206484756edfe37a0e4756f7cd5e60b650ea28f
VL  - 49
ER  -
TY  - JOUR
AB  - This article examines the effectiveness of school-based drug prevention programs in preventing illicit drug use. 

Our article reports the results of a systematic review of the evaluation literature to answer three fundamental questions: (1) do school-based drug prevention programs reduce rates of illicit drug use? (2) what features are characteristic of effective programs? and (3) do these effective program characteristics differ from those identified as effective in reviews of school-based drug prevention of licit substance use (such as alcohol and tobacco)? 

Using systematic review and meta-analytic techniques, we identify the characteristics of school-based drug prevention programs that have a significant and beneficial impact on ameliorating illicit substance use (i.e., narcotics) among young people. Successful intervention programs typically involve high levels of interactivity time-intensity, and universal approaches that are delivered in the middle school years. These program characteristics aligned with many of the effective program elements found in previous reviews exploring the impact of school-based drug prevention on licit drug use. 

Contrary to these past reviews, however, our analysis suggests that the inclusion of booster sessions and multifaceted drug prevention programs have little impact on preventing illicit drug use among school-aged children. Limitations of the current review and policy implications are discussed.
AD  - [Mazerolle, Lorraine; Rombouts, Sacha] Griffith Univ, ARC Ctr Excellence Policing &amp; Secur, Mt Gravatt, Qld 4122, Australia. [Soole, David W.] Queensland Univ Technol, Brisbane, Qld 4001, Australia. Mazerolle, L (reprint author), Griffith Univ, ARC Ctr Excellence Policing &amp; Secur, Messines Ridge Rd, Mt Gravatt, Qld 4122, Australia. l.mazerolle@griffith.edu.au
AN  - WOS:000258807500004
AU  - Soole,
AU  - D.
AU  - W.
AU  - Mazerolle,
AU  - L.
AU  - Rombouts,
AU  - S.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1375/acri.41.2.259
J2  - Aust. N. Z. J Criminol.
KW  - drug prevention meta-analysis illicit drug use ABUSE RESISTANCE EDUCATION COGNITIVE-BEHAVIORAL APPROACH LIONS-QUEST SKILLS FOLLOW-UP SUBSTANCE-ABUSE PROJECT DARE HIGH-RISK OUTCOME EVALUATION MARIJUANA USE YOUTH Criminology &amp; Penology
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 342TX Times Cited: 14 Cited Reference Count: 86 Soole, David W. Mazerolle, Lorraine Rombouts, Sacha Mazerolle, Lorraine/H-1958-2013 Mazerolle, Lorraine/0000-0002-3691-8644 15 SAGE PUBLICATIONS LTD LONDON AUST NZ J CRIMINOL
PY  - 2008
SP  - 259-286
T2  - Australian and New Zealand Journal of Criminology
TI  - School-based drug prevention programs: A review of what works
UR  - &lt;Go to ISI&gt;://WOS:000258807500004http://anj.sagepub.com/content/41/2/259http://anj.sagepub.com/content/41/2/259.full.pdf
VL  - 41
ER  -
TY  - JOUR
AB  - **Purpose:** 
This systematic review aimed to determine the effects of augmentative and alternative communication (AAC) intervention on speech production in children with autism or pervasive developmental disorder-not otherwise specified. 

**Method:** 
A systematic review methodology was utilized to limit bias in searching, selecting, coding, and synthesizing relevant treatment studies. This involved a multifaceted search for studies written between 1975 and May 2007 using various bibliographic databases, dissertation databases, hand searches of selected journals and published compilations of AAC theses and dissertations, and ancestry searches. To be included, studies had to meet stringent criteria. A coding manual and form facilitated data extraction in terms of participant characteristics, treatment characteristics, design and measurement, and outcomes. 

**Results:** 
Nine single-subject experimental design (27 participants) and 2 group studies (98 participants) were included. Results indicated that AAC interventions do not impede speech production. In fact, most studies reported an increase in speech production. However, in-depth analyses revealed. that the gains were rather modest. 

**Conclusions:** 
Although AAC interventions do not appear to impede speech production and may result in increased speech production, the modest gains observed require realistic expectations among clinicians and other stakeholders. Future research should be more hypothesis driven and aim to identify predictive child characteristics, such as prior speech imitation and object exploration skills.
AD  - [Schlosser, Ralf W.] Northeastern Univ, Dept Speech Language Pathol &amp; Audiol, Boston, MA 02115 USA. [Wendt, Oliver] Purdue Univ, W Lafayette, IN 47907 USA. Schlosser, RW (reprint author), Northeastern Univ, Dept Speech Language Pathol &amp; Audiol, 151B Forsyth, Boston, MA 02115 USA. r.schlosser@neu.edu
AN  - WOS:000258201400002
AU  - Schlosser,
AU  - R.
AU  - W.
AU  - Wendt,
AU  - O.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1044/1058-0360(2008/021
J2  - Am. J. Speech-Lang. Pathol.
KW  - augmentative and alternative communication autism spectrum disorders speech improvement systematic review SINGLE-SUBJECT RESEARCH DEVELOPMENTAL-DISABILITIES SIGN LANGUAGE PHASE-III PECS INDIVIDUALS ACQUISITION BEHAVIOR OUTPUT DISORDERS Audiology &amp; Speec
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 334DB Times Cited: 50 Cited Reference Count: 77 Schlosser, Ralf W. Wendt, Oliver 50 AMER SPEECH-LANGUAGE-HEARING ASSOC ROCKVILLE AM J SPEECH-LANG PAT
PY  - 2008
SP  - 212-230
T2  - American Journal of Speech-Language Pathology
TI  - Effects of augmentative and alternative communication intervention on speech production in children with autism: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000258201400002http://media.proquest.com/media/pq/classic/doc/1536974211/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Schlosser%2C+Ralf+W%3BWendt%2C+Oliver&amp;cit%3Atitle=Effects+of+Augmentative+and+Alternative+Communication+Intervention+on+...&amp;cit%3Apub=American+Journal+of+Speech+-+Language+Pathology&amp;cit%3Avol=17&amp;cit%3Aiss=3&amp;cit%3Apg=212&amp;cit%3Adate=Aug+2008&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYxOTEwMzYyOTY3Njo2NjQ1NzgSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFMzMzMzcyCTIwNDI2NTc0NToNRG9jdW1lbnRJbWFnZUIBMFIGT25saW5lWgJGVGIDUEZUagoyMDA4LzA4LzAxcgoyMDA4LzA4LzMxegCCASlQLTEwMDAyNzMtMzEwNzUtQ1VTVE9NRVItMTAwMDAxNTctMTExNTExMpIBBk9ubGluZcoBB0VuZE5vdGXSARJTY2hvbGFybHkgSm91cm5hbHOaAgdQcmVQYWlkqgIoT1M6RU1TLVBkZkRvY1ZpZXdCYXNlLWdldE1lZGlhVXJsRm9ySXRlbcoCD0FydGljbGV8RmVhdHVyZdICAVniAgFO8gIA&amp;_s=%2FvM%2B1XPJ9DMzzdiLFHuUzN9i%2BAY%3D
UR  - https://ajslp.pubs.asha.org/article.aspx?articleid=1757593
VL  - 17
ER  -
TY  - JOUR
AB  - **Background **
The safety of antidepressants in children and adolescents is being questioned and the efficacy of these drugs in juvenile depression remains uncertain. 

**Aims **
To assess antidepressant efficacy in juvenile depression. 

**Method **
Systematic review and meta-analysis of randomised controlled trials (RCTs) comparing responses to antidepressants, overall and by type, v. placebo in young people with depression. 

**Results **
Thirty drug-placebo contrasts in RCTs lasting 8 weeks (median) involved 3069 participants (512 person-years) of average age 13.5 years. Meta-analysis yielded a modest pooled drug/placebo response rate ratio (RR=1.22, 95% CI 1.15-1.31), with little separation between antidepressant types. Findings were similar for response rate differences and corresponding number needed to treat (NNT): overall NNT=9; tricyclic antidepressants NNT=14 &gt; serotonin reuptake inhibitors NNT=9 &gt; other antidepressants NNT=8. Numbers needed to treat decreased with increasing age: children (NNT=21) &gt; mixed ages (NNT=10) &gt; adolescents (NNT=8). 

**Conclusions **
Antidepressants of all types showed limited efficacy in juvenile depression, but fluoxetine might be more effective, especially in adolescents. Studies in children and in severely depressed, hospitalised or suicidal juvenile patients are needed, and effective, safe and readily accessible treatments for juvenile depression are urgently required. 

**Declaration of interest **
E.M.T. has received research support from Johnson &amp; Johnson Psychiatry Research and Development. L.T. has received research support or served as a consultant to JDS, IFI, Eli Lilly and Janssen Pharmaceutical Corporations. R.J.B. is a consultant to or has received research support from Janssen, IFI, JDS, Eli Lilly, Novartis and Solvay Pharmaceutical Corporations. 

Funding is detailed in the Acknowledgements.
AD  - [Tsapakis, Evangelia M.] Kings Coll London, Inst Psychiat, MRC Social Genet &amp; Dev Psychiat Ctr, London SE5 8AF, England. [Tsapakis, Evangelia M.] Kings Coll London, Inst Psychiat, Sect Clin Neuropharmacol, London SE5 8AF, England. [Tsapakis, Evangelia M.; Soldani, Federico; Tondo, Leonardo; Baldessarini, Ross J.] Harvard Univ, Sch Med, Dept Psychiat, Boston, MA 02115 USA. [Tsapakis, Evangelia M.; Soldani, Federico; Tondo, Leonardo; Baldessarini, Ross J.] Massachusetts Gen Hosp, McLean Div, Psychopharmacol Program, Boston, MA 02114 USA. [Soldani, Federico] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA. [Tondo, Leonardo] Univ Cagliari, Dept Psychol, Sardinia, Italy. [Tondo, Leonardo] Univ Cagliari, Lucio Bini Mood Disorder Ctr, Sardinia, Italy. [Baldessarini, Ross J.] Massachusetts Gen Hosp, Inst Consortium Bipolar Disorder Res, McLean Div, Boston, MA 02114 USA. Tsapakis, EM (reprint author), Kings Coll London, Inst Psychiat, MRC Social Genet &amp; Dev Psychiat Ctr, POB 80,De Crespigny Pk, London SE5 8AF, England. e.tsapakis@iop.kci.ac.uk
AN  - WOS:000257536500004
AU  - Tsapakis,
AU  - E.
AU  - M.
AU  - Soldani,
AU  - F.
AU  - Tondo,
AU  - L.
AU  - Baldessarini,
AU  - R.
AU  - J.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1192/bjp.bp.106.031088
J2  - Br. J. Psychiatry
KW  - PLACEBO-CONTROLLED TRIAL ADOLESCENT MAJOR DEPRESSION RANDOMIZED CONTROLLED-TRIALS PAST 10 YEARS DOUBLE-BLIND CHILDHOOD DEPRESSION PEDIATRIC-PATIENTS CLINICAL-TRIALS DESIPRAMINE TREATMENT ONSET DEPRESSION Psychiatry
L1  - internal-pdf://1688246088/Tsapakis-2008-Efficacy of antidepressants in j.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 324RU Times Cited: 68 Cited Reference Count: 79 Tsapakis, Evangelia M. Soldani, Federico Tondo, Leonardo Baldessarini, Ross J. 69 ROYAL COLLEGE OF PSYCHIATRISTS LONDON BRIT J PSYCHIAT
PY  - 2008
SP  - 10-17
T2  - British Journal of Psychiatry
TI  - Efficacy of antidepressants in juvenile depression: meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000257536500004http://bjp.rcpsych.org/content/bjprcpsych/193/1/10.full.pdf
UR  - http://bjp.rcpsych.org/content/bjprcpsych/193/1/10.full.pdf
VL  - 193
ER  -
TY  - JOUR
AB  - BACKGROUND: 
Supplementation of preterm formulas with long-chain polyunsaturated fatty acids (LCPUFAs) is based on their effectiveness to increase blood status and improve visual outcomes. Dispute remains over their efficacy on global development. 

OBJECTIVE: 
The objective was to compare the effects of LCPUFA-supplemented with those of control formulas on neurodevelopment and diseases associated with prematurity. DESIGN: We systematically reviewed randomized controlled trials involving preterm infants that tested LCPUFA-supplemented formulas. The weighted mean differences (WMDs) in neurodevelopmental scores and relative risk (RR) of disease were calculated to compare infants fed LCPUFA-supplemented formula with those fed control formula. 

RESULTS: 
No clear differences in Bayley Scales of Infant Development (BSID) scores were observed between groups. Mental development of LCPUFA-supplemented infants was 3.4 points higher than that of control infants with BSID version II (WMD: 3.44; 95% CI: 0.56, 6.31; P = 0.02; n = 879), although it was driven by 2 trials with large effect sizes and wide CIs. Psychomotor development was lower in supplemented infants tested with BSID version I (WMD: -7.99; 95% CI: -14.00, -1.99; P = 0.009; n = 87); however, it was limited by small sample sizes. No differences in the RR of sepsis (1.08; 95% CI: 0.79, 1.46; P = 0.63; n = 1333) or in the RR of necrotizing enterocolitis (1.13; 95% CI: 0.62, 2.04; P = 0.69; n = 1333) were found. Similarly, the risks of retinopathy of prematurity, intraventricular hemorrhage, and bronchopulmonary dysplasia were not different between groups, but data were limited by small sample sizes and trials with an increased risk of bias. 

CONCLUSIONS: 
LCPUFA-supplemented formula does not alter the risk of NEC or sepsis. Further work is needed to determine the extent of benefit of LCPUFA-supplemented formula on the mental development of preterm infants.
AD  - Smithers,Lisa G. Child Health Research Institute, Child, Youth and Women&#039;s Health Service, North Adelaide, Australia.
AN  - 18400714
AU  - Smithers,
AU  - L.
AU  - G.
AU  - Gibson,
AU  - R.
AU  - A
AU  - McPhee,
AU  - A.
AU  - Makrides,
AU  - M.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - ikke doi
DP  - Ovid Technologies
J2  - Am J Clin Nutr
KW  - *Child Development/de [Drug Effects] Child Development/ph [Physiology] Cognition/de [Drug Effects] Dietary Supplements Fatty Acids, Unsaturated/ad [Administration &amp; Dosage] Fatty Acids, Unsaturated/me [Metabolism] *Fatty Acids, Unsaturated/pd [Pharmacol
L1  - internal-pdf://3460884443/Smithers-2008-Effect of long-chain polyunsatur.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Smithers, Lisa G Gibson, Robert A McPhee, Andrew Makrides, Maria
PY  - 2008
SP  - 912-20
T2  - American Journal of Clinical Nutrition
TI  - Effect of long-chain polyunsaturated fatty acid supplementation of preterm infants on disease risk and neurodevelopment: a systematic review of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18400714
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18400714&amp;id=doi:&amp;issn=0002-9165&amp;isbn=&amp;volume=87&amp;issue=4&amp;spage=912&amp;pages=912-20&amp;date=2008&amp;title=American+Journal+of+Clinical+Nutrition&amp;atitle=Effect+of+long-chain+polyunsaturated+fatty+acid+supplementation+of+preterm+infants+on+disease+risk+and+neurodevelopment%3A+a+systematic+review+of+randomized+controlled+trials.&amp;aulast=Smithers&amp;pid=%3Cauthor%3ESmithers+LG%3C%2Fauthor%3E%3CAN%3E18400714%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ajcn.nutrition.org/content/87/4/912.full.pdf
UR  - http://ajcn.nutrition.org/content/87/4/912.full.pdf
VL  - 87
ER  -
TY  - JOUR
AB  - **Background**
Mental health conditions arising in the perinatal period, including depression, have the potential to impact negatively on not only the woman but also her partner, infant, and family. The capacity for routine, universal antenatal psychosocial assessment, and thus the potential for reduction of morbidity, is very significant.

**Objectives**
To evaluate the impact of antenatal psychosocial assessment on perinatal mental health morbidity.

**Search methods**
We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register, the Cochrane Depression, Anxiety and Neurosis Group&#039;s Trials Register (CCDAN TR‐Studies), HSRProj in the National Library of Medicine (USA), and the Current Controlled Trials website: http://www.controlled trials.com/ and the UK National Research Register (last searched March 2008).

**Selection criteria**
Randomised and quasi‐randomised controlled trials.

**Data collection and analysis**
At least two review authors independently assessed trials for eligibility; they also extracted data from included trials and assessed the trials for potential bias.

**Main results**
Two trials met criteria for an RCT of antenatal psychosocial assessment. One trial examined the impact of an antenatal tool (ALPHA) on clinician awareness of psychosocial risk, and the capacity of the antenatal ALPHA to predict women with elevated postnatal Edinburgh Depression Scale (EDS) scores, finding a trend towards increased clinician awareness of &#039;high level&#039; psychosocial risk where the ALPHA intervention had been used (relative risk (RR) 4.61 95% confidence interval (CI) 0.99 to 21.39). No differences between groups were seen for numbers of women with antenatal EDS scores, a score of greater than 9 being identified by ALPHA as of concern for depression (RR 0.69 95% CI 0.35 to 1.38); 139 providers. The other trial reported no differences in EPS scores greater than 12 at 16 weeks postpartum between the intervention (communication about the EDS scores with the woman and her healthcare providers plus a patient information booklet) and the standard care groups (RR 0.86 95% CI 0.61 to 1.21; 371 women).

**Authors&#039; conclusions**
While the use of an antenatal psychosocial assessment may increase the clinician&#039;s awareness of psychosocial risk, neither of these small studies provides sufficient evidence that routine antenatal psychosocial assessment by itself leads to improved perinatal mental health outcomes. Further studies with better sample size and statistical power are required to further explore this important public health issue. It will also be important to examine outcomes up to one year postpartum not only for mother, but also infant and family.
AN  - CD005124
AU  - Austin,
AU  - M.
AU  - P.
AU  - Priest,
AU  - S.
AU  - R.
AU  - Sullivan,
AU  - E.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd005124.pub2
KW  - Prenatal Care
KW  - Anxiety Disorders [diagnosis] [prevention &amp; control]
KW  - Depression, Postpartum [diagnosis] [prevention &amp; control]
KW  - Mental Health
KW  - Puerperal Disorders [diagnosis] [prevention &amp; control] [psychology]
KW  - Randomized Controlled Trials as Topic
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Pregnancy[checkword]
KW  - Preg
PY  - 2008
T2  - Cochrane Database of Systematic Reviews
TI  - Antenatal psychosocial assessment for reducing perinatal mental health morbidity
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005124.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005124.pub2/asset/CD005124.pdf?v=1&amp;t=iw7inzmz&amp;s=d5789efb6a2a209c28c416a7f55a41f88e2ea8e8
ER  -
TY  - JOUR
AB  - Research on effectiveness of school bullying interventions has lagged behind descriptive studies on this topic. The literature on bullying intervention research has only recently expanded to a point that allows for synthesis of findings across studies. 

The authors conducted a meta-analytic study of school bullying intervention research across the 25-year period from 1980 through 2004, identifying 16 studies that met our inclusion criteria. These studies included 15,386 K through 12 student participants from European nations and the United States. Applying standard meta-analysis techniques to obtain averaged effect size estimates across similar outcomes, the authors found that the intervention studies produced meaningful and clinically important positive effects for about one-third of the variables. 

The majority of outcomes evidenced no meaningful change, positive or negative. 

The authors conclude that school bullying interventions may produce modest positive outcomes, that they are more likely to influence knowledge, attitudes, and self-perceptions rather than actual bullying behaviors; and that the majority of outcome variables in intervention studies are not meaningfully impacted.
AD  - [Merrell, Kenneth W.; Gueldner, Barbara A.; Ross, Scott W.] Univ Oregon, Dept Special Educ &amp; Clin Sci, Eugene, OR 97403 USA. Merrell, KW (reprint author), 5208 Univ Oregon, Sch Psychol Program, Eugene, OR 97403 USA. kmerrell@uoregon.edu
AN  - WOS:000257731300004
AU  - Merrell,
AU  - K.
AU  - W.
AU  - Gueldner,
AU  - B.
AU  - A.
AU  - Ross,
AU  - S.
AU  - W.
AU  - Isava,
AU  - D.
AU  - M.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1037/1045-3830.23.1.26
J2  - Sch. Psychol. Q.
KW  - schools bullying intervention violence prevention meta-analysis BEHAVIOR VICTIMS CHILDREN Psychology, Educational
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 327LT Times Cited: 142 Cited Reference Count: 39 Merrell, Kenneth W. Gueldner, Barbara A. Ross, Scott W. Isava, Duane M. 144 AMER PSYCHOLOGICAL ASSOC WASHINGTON SCHOOL PSYCHOL QUART
PY  - 2008
SP  - 26-42
T2  - School Psychology Quarterly
TI  - How effective are school bullying intervention programs? A meta-analysis of intervention research
UR  - &lt;Go to ISI&gt;://WOS:000257731300004
VL  - 23
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Meta-analytic procedures are used to review the literature of combined treatments of psychosocial and pharmacological treatments for children diagnosed with ADHD. 

**METHOD: **
Eight combined treatment studies meet specific inclusion and exclusion criteria regarding the core and peripheral features of the disorder. 

**RESULTS: **
The results of this study highlight the individual and average effect sizes within the categories of inattention, hyperactivity, impulsivity, social skills, and academics. These findings are compared with the effect sizes of meta-analytic findings previously reported in the pharmacological literature. 

**CONCLUSION: **
The results reveal large effect sizes for the core features of the disorder and the peripheral feature of social skills. A small effect size is found for the peripheral feature of academics. Findings are discussed in light of the paucity of included studies focused on combined treatments for ADHD.
AD  - Majewicz-Hefley,Amy. College of Education, Michigan State University, MI, USA.
AN  - 17242418
AU  - Majewicz-Hefley,
AU  - A.
AU  - Carlson,
AU  - J.
AU  - S.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1177/1087054706289934
DP  - Ovid Technologies
J2  - J Atten Disord
KW  - Attention Deficit Disorder with Hyperactivity/di [Diagnosis] Attention Deficit Disorder with Hyperactivity/px [Psychology] *Attention Deficit Disorder with Hyperactivity/th [Therapy] *Behavior Therapy *Central Nervous System Stimulants/tu [Therapeutic U
LA  - English
M3  - Meta-Analysis
N1  - Majewicz-Hefley, Amy Carlson, John S
PY  - 2007
SP  - 239-50
T2  - Journal of Attention Disorders
TI  - A meta-analysis of combined treatments for children diagnosed with ADHD
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17242418 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17242418&amp;id=doi:&amp;issn=1087-0547&amp;isbn=&amp;volume=10&amp;issue=3&amp;spage=239&amp;pages=239-50&amp;date=2007&amp;title=Journal+of+Attention+Disorders&amp;atitle=A+meta-analysis+of+combined+treatments+for+children+diagnosed+with+ADHD.&amp;aulast=Majewicz-Hefley&amp;pid=%3Cauthor%3EMajewicz-Hefley+A%3C%2Fauthor%3E%3CAN%3E17242418%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://jad.sagepub.com/content/10/3/239.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/1087054706289934?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 10
ER  -
TY  - JOUR
AB  - **BACKGROUND:** 
At any given time, 14% of Canadian children experience clinically significant mental disorders, which frequently persist into adulthood. Canadian public policy has emphasized specialized treatment services, yet these services only reach 25% of children with disorders. Prevention programs hold potential to reduce the number of children with disorders in the population. To inform policy-making, we systematically reviewed the best available research evidence on programs for preventing conduct disorder (CD), anxiety and depression, three of the most prevalent mental disorders in children. 

**METHODS: **
We systematically identified and reviewed randomized controlled trials (RCTs) on programs intended to prevent CD, anxiety and depression in children aged 0-18 years. 

**RESULTS: **
Fifteen RCTs met selection criteria: nine (on eight programs) for preventing CD; one for anxiety; four (on three programs) for depression; and one for all three. Ten RCTs demonstrated significant reductions in child symptom and/or diagnostic measures at follow-up. The most noteworthy programs, for CD, targeted at-risk children in the early years using parent training (PT) or child social skills training (SST); for anxiety, employed universal cognitive-behavioural training (CBT) in school-age children; and for depression, targeted at-risk school-age children, also using CBT. Effect sizes for these noteworthy programs were modest but consequential. There were few Canadian studies and few that evaluated costs. 

**DISCUSSION: **
Prevention programs are promising but replication RCTs are needed to determine effectiveness and cost-effectiveness in Canadian settings. Four program types should be priorities for replication: targeted PTand child SST for preventing CD in children&#039;s early years; and universal and targeted CBTfor preventing anxiety and depression in children&#039;s school-age years. Conducting RCTs through research-policy partnerships would enable implementation in realistic settings while ensuring rigorous evaluation. Prevention merits new policy and research investments as part of a comprehensive public health strategy to improve children&#039;s mental health in the population.
AD  - Waddell,Charlotte. Children&#039;s Health Policy Centre, Faculty of Health Sciences, Simon Fraser University, Vancouver, BC. charlotte_waddell@sfu.ca
AN  - 17626378
AU  - Waddell,
AU  - C.
AU  - Hua,
AU  - J.
AU  - M.
AU  - Garland,
AU  - O.
AU  - M.
AU  - Peters,
AU  - R.
AU  - D.
AU  - McEwan,
AU  - K.
DA  - May-Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - http://journal.cpha.ca/index.php/cjph/article/view/812/812
DP  - Ovid Technologies
J2  - Can J Public Health
KW  - Adolescent *Anxiety Disorders/pc [Prevention &amp; Control] Canada Child Child, Preschool *Conduct Disorder/pc [Prevention &amp; Control] *Depressive Disorder/pc [Prevention &amp; Control] *Evidence-Based Medicine *Health Policy Humans Infant Infant, Newborn *Menta
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Review
N1  - Waddell, Charlotte Hua, Josephine M Garland, Orion M Peters, Ray DeV McEwan, Kimberley
PY  - 2007
SP  - 166-73
T2  - Canadian Journal of Public Health. Revue Canadienne de Sante Publique
TI  - Preventing mental disorders in children: a systematic review to inform policy-making
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17626378 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17626378&amp;id=doi:&amp;issn=0008-4263&amp;isbn=&amp;volume=98&amp;issue=3&amp;spage=166&amp;pages=166-73&amp;date=2007&amp;title=Canadian+Journal+of+Public+Health.+Revue+Canadienne+de+Sante+Publique&amp;atitle=Preventing+mental+disorders+in+children%3A+a+systematic+review+to+inform+policy-making.&amp;aulast=Waddell&amp;pid=%3Cauthor%3EWaddell+C%3C%2Fauthor%3E%3CAN%3E17626378%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://media.proquest.com/media/pq/classic/doc/1323309241/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Waddell%2C+Charlotte%3BHua%2C+Josephine+M%3BGarland%2C+Orion+M%3BPeters%2C+Ray+DeV%3BMcEwan%2C+Kimberley&amp;cit%3Atitle=Preventing+Mental+Disorders+in+Children%3A+A+Systematic+Review+to+Inform+Policy-Making&amp;cit%3Apub=Canadian+Journal+of+Public+Health&amp;cit%3Avol=98&amp;cit%3Aiss=3&amp;cit%3Apg=166&amp;cit%3Adate=May%2FJun+2007&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMjA4Mjk0MjEwNTo4Nzg1OTUSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNDc2NDkyCTIzMTk5NjA4NDoNRG9jdW1lbnRJbWFnZUIBMFIGT25saW5lWgJGVGIDUEZUagoyMDA3LzA1LzAxcgoyMDA3LzA2LzMwegCCASlQLTEwMDAyNzMtMzEwNzUtQ1VTVE9NRVItMTAwMDAxNTctMTExNTExMpIBBk9ubGluZcoBB0VuZE5vdGXSARJTY2hvbGFybHkgSm91cm5hbHOaAgdQcmVQYWlkqgIoT1M6RU1TLVBkZkRvY1ZpZXdCYXNlLWdldE1lZGlhVXJsRm9ySXRlbcoCD0ZlYXR1cmV8QXJ0aWNsZdICAVniAgFO8gIA&amp;_s=QEmMEKr40Tmyn%2BF27R9jV7bD90I%3D
VL  - 98
ER  -
TY  - JOUR
AB  - **Background:** 
Psychological treatments are commonly used in the management of anxiety. Certain types of psychological treatments are well suited to needs of people with traumatic brain injury (TBI). We have systematically reviewed studies examining the effectiveness of these approaches for TBI.Objectives: To assess the effects of psychological treatments for anxiety in people with TBI.

**Search methods:**
We searched the following databases up until March 2006: Cochrane Injuries Group&#039;s specialised register, Cochrane Depression, Anxiety and Neurosis Group&#039;s specialised register, Cochrane Central Register of Controlled Trials, MEDLINE, PsycINFO, EMBASE, CINAHL, AMED, ERIC, and PsycBITETM. Additionally, key journals were handsearched and reference lists of included trials were examined to identify further studies meeting inclusion criteria.

**Selection criteria:** 
Randomised controlled trials of psychological treatments for anxiety, with or without pharmacological treatment, for people with TBI were included in the review. Pharmacological treatments for anxiety in isolation (without psychological intervention) were excluded.

**Data collection and analysis:**
Two authors independently assessed methodological quality and extracted data from the included trials.

**Main results:**
Three trials were identified in this review as satisfying inclusion criteria. Results of all three trials were evaluated, however, one of these trials had compromised methodological quality and, therefore the focus was placed on the other two trials. Data were not pooled due to the heterogeneity between trials. The first trial (n = 24) showed a benefit of cognitive behavioural therapy (CBT) in people with mild TBI and acute stress disorder. Fewer people receiving CBT had diagnosis of post-traumatic stress disorder (PTSD) at post-treatment compared to the control supportive counselling group, with maintenance of treatment gains found at six-month follow up. The second trial (n = 20) showed that post-treatment anxiety symptomatology of people with mild to moderate TBI was lower in the combined CBT and neurorehabilitation group compared to the no intervention control group.

**Authors&#039; conclusions:** 
This review provides some evidence for the effectiveness of CBT for treatment of acute stress disorder following mild TBI and CBT combined with neurorehabilitation for targeting general anxiety symptomatology in people with mild to moderate TBI. These findings need to be viewed in light of the small number, small sample size and heterogeneous characteristics of current trials published in this area. More trials focusing on comparable psychological interventions, severity of injury of participants and diagnosis of anxiety disorder(s) are needed.
AN  - CD005239
AU  - Soo,
AU  - C.
AU  - Tate,
AU  - R.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd005239.pub2
KW  - Anxiety [therapy]
KW  - Brain Injuries [psychology]
KW  - Psychotherapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Male[checkword]
KW  - Inj
PY  - 2007
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological treatment for anxiety in people with traumatic brain injury
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005239.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005239.pub2/asset/CD005239.pdf?v=1&amp;t=iw7kv34r&amp;s=c56d634da2161764285a86e68dcd4481f0e46f86
ER  -
TY  - JOUR
AB  - **Background **
People with depression often experience interpersonal problems. Family therapy for depression is a widely used intervention, but it is unclear whether this is an effective therapy for the treatment of depression. 

**Objectives **
To assess the efficacy of family therapy for depression. Search strategy The following electronic databases were searched using a specific search strategy: CCDANCTR- Studies and CCDANCTR- References searched on 21/ 10/ 2005, The Cochrane Central Register of Controlled Trials, Medline ( 1966 to January 2005), EMBASE ( 1980 to January 2005), Psycinfo ( 1974 to January 2005). Reference lists of articles were also searched. Handsearches of relevant journals and bibliographies were conducted and first authors of included studies and experts in the field were contacted for further information. 

**Selection criteria **
Included studies were randomised controlled and controlled clinical trials comparing family therapy with no intervention or an alternative intervention in which depression symptomatology was a main outcome measure. 

**Data collection and analysis **
Methodological qualitywas independently assessed by two review authors using theMaastricht- AmsterdamCriteria List. The qualitative and quantitative characteristics of the selected trials were independently extracted by three review authors using a standardised data extraction form. Levels of evidence were used to determine the strength of the evidence available. It was not possible to perform metaanalyses because of the heterogeneity of the selected studies. 

**Main results **
Three high- quality and three low- quality studies, involving 519 people with depression, were identified. The studies were very heterogeneous in terms of interventions, participants, and measuring instruments. Despite fairly good methodological quality and positive findings of some studies, evidence for the effectiveness of family therapy for depression did not exceed level 3 ( limited or conflicting evidence), except formoderate evidence ( level 2), based on the non- combined findings fromthree studies, indicating that family therapy is more effective than no treatment or waiting list condition on decreasing depression, and on increasing family functioning. 

**Author&#039;s conclusions **
The current evidence base is too heterogeneous and sparse to draw conclusions on the overall effectiveness of family therapy in the treatment of depression. At this point, use of psychological interventions for the treatment of depression for which there is already an evidence- base would seem to be preferable to family therapy. Further high quality trials examining the effectiveness and comparative effectiveness of explicitly defined forms of family therapy are required.
AD  - Maastricht Univ, Dept Med Clin &amp; Expt Psychol, NL-6221 VA Maastricht, Netherlands. Henken, HT (reprint author), Maastricht Univ, Dept Med Clin &amp; Expt Psychol, Duitse Poort 15, NL-6221 VA Maastricht, Netherlands.
AN  - WOS:000248118000106
AU  - Henken,
AU  - H.
AU  - T.
AU  - Huibers,
AU  - M.
AU  - J.
AU  - H.
AU  - Churchill,
AU  - R.
AU  - Restifo,
AU  - K.
AU  - Roelofs,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD006728
J2  - Cochrane Database Syst Rev.
KW  - RANDOMIZED CLINICAL-TRIAL MULTIFAMILY PSYCHOEDUCATION GROUPS ADOLESCENT DEPRESSION FOLLOW-UP SYSTEMATIC REVIEWS PREVENTIVE INTERVENTIONS BEREAVEMENT PROGRAM PSYCHOTHERAPY TRIAL AFFECTIVE-DISORDERS COST-EFFECTIVENESS Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 191FZ Times Cited: 7 Cited Reference Count: 86 Henken, H. T. Huibers, M. J. H. Churchill, R. Restifo, K. Roelofs, J. 7 JOHN WILEY &amp; SONS LTD CHICHESTER COCHRANE DB SYST REV
PY  - 2007
SP  - 25
T2  - Cochrane Database of Systematic Reviews
TI  - Family therapy for depression
UR  - &lt;Go to ISI&gt;://WOS:000248118000106http://onlinelibrary.wiley.com/store/10.1002/14651858.CD006728/asset/CD006728.pdf?v=1&amp;t=ib7ti8oo&amp;s=33ddea5308902ea0f46fbf4e1a3834fff14020b2
ER  -
TY  - JOUR
AB  - This research synthesized results from 66 published and unpublished evaluations of incarceration-based drug treatment programs using meta-analysis. Incarceration-based drug treatment programs fell into five types: therapeutic communities (TCs), residential substance abuse treatment (RSAT), group counseling, boot camps specifically for drug offenders, and narcotic maintenance programs. We examined the effectiveness of each of these types of interventions in reducing post-release offending and drug use, and we also examined whether differences in research findings can be explained by variations in methodology, sample, or program features. Our results consistently found support for the effectiveness of TC programs on both outcome measures, and this finding was robust to variations in method, sample, and program features. We also found support for the effectiveness of RSAT and group counseling programs in reducing re-offending, but these programs&#039; effects on drug use were ambiguous. A limited number of evaluations assessed narcotic maintenance or boot camp programs; however, the existing evaluations found mixed support for maintenance programs and no support for boot camps. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Mitchell, Ojmarrh: ojmarrh.mitchell@uc.edu; Wilson, David B.: dwilsonb@gmu.edu; MacKenzie, Doris L.: dmackenzie@crim.umd.edu Mitchell, Ojmarrh: Division of Criminal Justice, University of Cincinnati, 600 Dyer Hall, PO Box 210389, Cincinnati, OH, US, 45221-0389, ojmarrh.mitchell@uc.edu Mitchell, Ojmarrh: Division of Criminal Justice, University of Cincinnati, Cincinnati, OH, US Wilson, David B.: Administration of Justice, George Mason University, Manassas, VA, US MacKenzie, Doris L.: Department of Criminology and Criminal Justice, University of Maryland, College Park, MD, US
AN  - 2008-00669-004
AU  - Mitchell,
AU  - O.
AU  - Wilson,
AU  - D.
AU  - B.
AU  - MacKenzie,
AU  - D.
AU  - L.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s11292-007-9040-2
DP  - Ovid Technologies
KW  - recidivism, therapeutic communities, incarceration-based drug treatment programs, meta-analysis, interventions, drug use residential substance abuse treatment, group counseling, boot camps *Drug Abuse *Drug Rehabilitation *Incarceration *Meta Analysis *
LA  - English
M3  - Empirical Study; Quantitative Study
PY  - 2007
SP  - 353-375
T2  - Journal of Experimental Criminology
TI  - Does incarceration-based drug treatment reduce recidivism? A meta-analytic synthesis of the research
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc5&amp;AN=2008-00669-004 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs11292-007-9040-2&amp;issn=1573-3750&amp;isbn=&amp;volume=3&amp;issue=4&amp;spage=353&amp;pages=353-375&amp;date=2007&amp;title=Journal+of+Experimental+Criminology&amp;atitle=Does+incarceration-based+drug+treatment+reduce+recidivism%3F+A+meta-analytic+synthesis+of+the+research.&amp;aulast=Mitchell&amp;pid=%3Cauthor%3EMitchell%2C+Ojmarrh%3C%2Fauthor%3E%3CAN%3E2008-00669-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs11292-007-9040-2http://download.springer.com/static/pdf/475/art%253A10.1007%252Fs11292-007-9040-2.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs11292-007-9040-2&amp;token2=exp=1435232693~acl=%2Fstatic%2Fpdf%2F475%2Fart%25253A10.1007%25252Fs11292-007-9040-2.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs11292-007-9040-2*~hmac=a72ac635a127e120b0f964924b43f31ad52effcc489e287affe1e4287aaf9055
VL  - 3
ER  -
TY  - JOUR
AB  - **Rationale** 
Pharmacotherapy is frequently considered in the treatment of disruptive behavior disorders (DBDs) in children and adolescents. There are, however, no systematic reviews of this literature. 

** Objectives**  
The aim of this work is to determine whether medication is effective in treating pediatric disruptive behavior disorders and related problems of impulse control, as well as to examine differences in the treatment response and tolerability of different medication classes and agents. 

** Materials and methods**  
Randomized controlled trials of the pharmacotherapy of DBDs in children and adolescents were reviewed, and a meta-analysis of 14 trials (823 participants) was conducted. 

** Results**  
There is some evidence of the effectiveness of medication in treating DBDs, with positive outcomes for lithium and risperidone in particular. Pharmacotherapy also demonstrated some efficacy in reducing symptoms of aggression. Medication was relatively well-tolerated, as indicated by equivalent dropout rates in medication and comparison groups. 

** Conclusions ** 
There are relatively few controlled trials of the pharmacotherapy of disruptive behavior disorders or other impulse control disorders, despite the importance of research in this area. Given the potential adverse effects of agents such as lithium and risperidone, a careful risk-benefit analysis is needed for each patient.
AD  - Univ Stellenbosch, Dept Psychiat, MRC Anxiety &amp; Stress Disorders Res Unit, ZA-7600 Stellenbosch, South Africa. Univ Cape Town, Dept Psychiat &amp; Mental Hlth, ZA-7925 Cape Town, South Africa. Ipser, J (reprint author), Univ Stellenbosch, Dept Psychiat, MRC Anxiety &amp; Stress Disorders Res Unit, ZA-7600 Stellenbosch, South Africa. jipser@sun.ac.za
AN  - WOS:000244304000012
AU  - Ipser,
AU  - J.
AU  - Stein,
AU  - D.
AU  - J.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00213-006-0537-6
J2  - Psychopharmacology
KW  - pediatric pharmacotherapy impulse control disorders disruptive behavior disorders conduct disorder oppositional defiant disorder metaanalysis systematic review OPPOSITIONAL DEFIANT DISORDER ATTENTION-DEFICIT/HYPERACTIVITY DISORDER DEFICIT HYPERACTIVITY
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 137PH Times Cited: 23 Cited Reference Count: 78 Ipser, Jonathan Stein, Dan J. Ipser, Jonathan/C-1354-2008; Stein, Dan/A-1752-2008 Stein, Dan/0000-0001-7218-7810 23 SPRINGER NEW YORK PSYCHOPHARMACOLOGY
PY  - 2007
SP  - 127-140
T2  - Psychopharmacology
TI  - Systematic review of pharmacotherapy of disruptive behavior disorders in children and adolescents
UR  - &lt;Go to ISI&gt;://WOS:000244304000012
UR  - https://link.springer.com/article/10.1007%2Fs00213-006-0537-6
VL  - 191
ER  -
TY  - JOUR
AB  - This systematic review evaluates the efficacy of cognitive-behavioral therapy (CBT) in improving selfesteem among depressed adolescents aged 13-18 years. 

A search identified 265 references, 33 articles were acquired, of which two papers met the inclusion criteria. 

Two excluded studies are also discussed.

A total of 82 participants from two trials were included in the meta-analysis. 

The data suggest CBT may be an effective treatment for increasing global and academic self-esteem when compared to wait-list controls. 

However, more research is needed due to the limited number of studies conducted in this area and the need for further investigation into the long-term effects of CBT. 

(c) 2007 Elsevier Ltd. All rights reserved.
AD  - Univ Oxford, Dept Social Policy &amp; Social Work, Ctr Evidence Based Intervent, Oxford OX1 2ER, England. Taylor, TL (reprint author), Univ Oxford, Dept Social Policy &amp; Social Work, Ctr Evidence Based Intervent, Barnett House,32 Wellington Sch, Oxford OX1 2ER, England. tatiana.taylor@gmail.com
AN  - WOS:000248173300001
AU  - Taylor,
AU  - T.
AU  - L.
AU  - Montgomery,
AU  - P.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.childyouth.2007.01.010
J2  - Child. Youth Serv. Rev.
KW  - cognitive-behavioral therapy self-esteem depression MAJOR DEPRESSION COMMUNITY SAMPLE DISORDERS CHILDREN EFFICACY CHILDHOOD PHARMACOTHERAPY PSYCHOTHERAPY FAMILY TRIAL Family Studies Social Work
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 192AO Times Cited: 12 Cited Reference Count: 46 Taylor, Tatiana L. Montgomery, Paul 12 PERGAMON-ELSEVIER SCIENCE LTD OXFORD CHILD YOUTH SERV REV
PY  - 2007
SP  - 823-839
T2  - Children and Youth Services Review
TI  - Can cognitive-behavioral therapy increase self-esteem among depressed adolescents? A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000248173300001http://ac.els-cdn.com/S0190740907000345/1-s2.0-S0190740907000345-main.pdf?_tid=356121ee-18cd-11e5-b4f1-00000aacb35e&amp;acdnat=1434970714_50514aee858741f3beade6753c529704
VL  - 29
ER  -
TY  - JOUR
AB  - **Background** 
Recent estimates concerning the prevalence of autism spectrum disorder (ASD) suggest that at least one in 200 children is affected. This group of children and families have important service needs. The involvement of parents in implementing intervention strategies designed to help their autistic children has long been accepted as helpful. The potential benefits are increased skills and reduced stress for parents as well as children. 

**Methods**** 
This research review focused on interventions for children aged 1-6 years, and was carried out using systematic methodology: a comprehensive search of psychological, educational and biomedical databases, as well as bibliographies and reference lists of key articles, contact with experts in the field, and hand search of key journals. Only studies which involved a concurrent element of control were included. 

**Results** 
The review found very few studies that had adequate research design from which to draw conclusions about the effectiveness of parent-implemented early intervention. Both randomized and controlled studies tended to suggest that parent training leads to improved child communicative behaviour, increased maternal knowledge of autism, enhanced maternal communication style and parent child interaction, and reduced maternal depression. 

**Conclusion** 
It seems that parent training can successfully contribute to intervention for young children with ASD. However, the review highlights the need for improved research in this area.
AD  - Univ Newcastle Upon Tyne, Royal Victoria Infirm, Sir James Spence Inst, Sch Clin Med Sci, Newcastle Upon Tyne NE1 4LP, Tyne &amp; Wear, England. McConachie, H (reprint author), Univ Newcastle Upon Tyne, Royal Victoria Infirm, Sir James Spence Inst, Sch Clin Med Sci, Newcastle Upon Tyne NE1 4LP, Tyne &amp; Wear, England. h.r.mcconachie@newcastle.ac.uk
AN  - WOS:000244003900020
AU  - McConachie,
AU  - H.
AU  - Diggle,
AU  - T.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1111/j.1365-2753.2006.00674.x
J2  - J. Eval. Clin. Pract.
KW  - autism spectrum disorder communication early intervention parental stress parent-child interaction systematic review PERVASIVE DEVELOPMENTAL DISORDERS INTENSIVE EARLY INTERVENTION BEHAVIORAL TREATMENT PRESCHOOL-CHILDREN TRAINING-PROGRAM FOLLOW-UP TRIAL
L1  - internal-pdf://3594170355/McConachie-2007-Parent implemented early inter.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 133HL Times Cited: 77 Cited Reference Count: 66 McConachie, Helen Diggle, Tim 77 BLACKWELL PUBLISHING OXFORD J EVAL CLIN PRACT
PY  - 2007
SP  - 120-129
T2  - Journal of Evaluation in Clinical Practice
TI  - Parent implemented early intervention for young children with autism spectrum disorder: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000244003900020http://onlinelibrary.wiley.com/store/10.1111/j.1365-2753.2006.00674.x/asset/j.1365-2753.2006.00674.x.pdf?v=1&amp;t=ib3i5d8g&amp;s=ed28dc23b853f70bc222e7f8cb3b012ef1acd6c4
UR  - http://onlinelibrary.wiley.com/store/10.1111/j.1365-2753.2006.00674.x/asset/j.1365-2753.2006.00674.x.pdf?v=1&amp;t=j8yexy7o&amp;s=51f4643ecab4e8fe595e8a565f7c1ea4fe0bc67a
VL  - 13
ER  -
TY  - JOUR
AB  - We conducted a review and meta-analyses of 24 studies to evaluate and compare the outcomes of two widely disseminated parenting interventions-Parent-Child Interaction Therapy and Triple P-Positive Parenting Program. 

Participants in all studies were caregivers and 3- to 12-year-old children. In general, our analyses revealed positive effects of both interventions, but effects varied depending on intervention length, components, and source of outcome data. 

Both interventions reduced parent-reported child behavior and parenting problems. The effect sizes for PCIT were large when outcomes of child and parent behaviors were assessed with parent-report, with the exclusion of Abbreviated PCIT, which had moderate effect sizes. 

All forms of Triple P had moderate to large effects when outcomes were parent-reported child behaviors and parenting, with the exception of Media Triple P, which had small effects. PCIT and an enhanced version of Triple P were associated with improvements in observed child behaviors. 

These findings provide information about the relative efficacy of two programs that have received substantial funding in the USA and Australia, and findings should assist in making decisions about allocations of funding and dissemination of these parenting interventions in the future.
AD  - Thomas,Rae. Gold Coast Campus and Griffith Psychological Health Research Centre, School of Psychology, Griffith University, GPY, PMB 50 GCMC, Brisbane, QLD 9726, Australia. r.thomas@griffith.edu.au
AN  - 17333363
AU  - Thomas,
AU  - R.
AU  - Zimmer-Gembeck,
AU  - M.
AU  - J.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10802-007-9104-9
DP  - Ovid Technologies
J2  - J Abnorm Child Psychol
KW  - Adult Australia *Behavior Therapy/mt [Methods] Child Child Behavior Disorders/pc [Prevention &amp; Control] Child Behavior Disorders/px [Psychology] *Child Behavior Disorders/th [Therapy] Child, Preschool *Education/mt [Methods] *Family Therapy/mt [Methods]
LA  - English
M3  - Meta-Analysis Review
N1  - Thomas, Rae Zimmer-Gembeck, Melanie J
PY  - 2007
SP  - 475-95
T2  - Journal of Abnormal Child Psychology
TI  - Behavioral outcomes of Parent-Child Interaction Therapy and Triple P-Positive Parenting Program: a review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17333363
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17333363&amp;id=doi:&amp;issn=0091-0627&amp;isbn=&amp;volume=35&amp;issue=3&amp;spage=475&amp;pages=475-95&amp;date=2007&amp;title=Journal+of+Abnormal+Child+Psychology&amp;atitle=Behavioral+outcomes+of+Parent-Child+Interaction+Therapy+and+Triple+P-Positive+Parenting+Program%3A+a+review+and+meta-analysis.&amp;aulast=Thomas&amp;pid=%3Cauthor%3EThomas+R%3C%2Fauthor%3E%3CAN%3E17333363%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10802-007-9104-9
VL  - 35
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
A growing number of observational and epidemiological studies have suggested that mental illness, in particular mood disorders, is associated with reduced dietary intake and/or cellular abundance of omega-3 polyunsaturated fatty acids (PUFA). This has prompted researchers to test the efficacy of omega-3 PUFA in a range of different psychiatric disorders. We have critically reviewed the double blind placebo controlled clinical trials published prior to April 2007 to determine whether omega-3 PUFA are likely to be efficacious in these disorders. 

**RESULTS: **
Most trials involved a small number of participants but were largely well designed. Omega-3 PUFA were well tolerated by both children and adults with mild gastrointestinal effects being the only consistently reported adverse event. For schizophrenia and borderline personality disorder we found little evidence of a robust clinically relevant effect. In the case of attention deficit hyperactivity disorder and related disorders, most trials showed at most small benefits over placebo. A limited meta-analysis of these trials suggested that benefits of omega-3 PUFA supplementation may be greater in a classroom setting than at home. Some evidence indicates that omega-3 PUFA may reduce symptoms of anxiety although the data is preliminary and inconclusive. The most convincing evidence for beneficial effects of omega-3 PUFA is to be found in mood disorders. A meta-analysis of trials involving patients with major depressive disorder and bipolar disorder provided evidence that omega-3 PUFA supplementation reduces symptoms of depression. Furthermore, meta-regression analysis suggests that supplementation with eicosapentaenoic acid may be more beneficial in mood disorders than with docosahexaenoic acid, although several confounding factors prevented a definitive conclusion being made regarding which species of omega-3 PUFA is most beneficial. The mechanisms underlying the apparent efficacy of omega-3 PUFA in mood disorders compared to schizophrenia are discussed as is a rational for the possibly greater efficacy of EPA compared to DHA.

**CONCLUSION: **
While it is not currently possible to recommend omega-3 PUFA as either a mono- or adjunctive-therapy in any mental illness, the available evidence is strong enough to justify continued study, especially with regard to attentional, anxiety and mood disorders.
AD  - Ross,Brian M. Northern Ontario School of Medicine, Public Health Program, and Department of Chemistry, Lakehead University, Thunder Bay, Ontario, Canada. brian.ross@normed.ca
AN  - 17877810
AU  - Ross,
AU  - B.
AU  - M.
AU  - Seguin,
AU  - J.
AU  - Sieswerda,
AU  - L.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1186/1476-511X-6-21
DP  - Ovid Technologies
J2  - Lipids health dis
KW  - Animals Fatty Acids, Omega-3/cl [Classification] *Fatty Acids, Omega-3/tu [Therapeutic Use] Humans *Mental Disorders/dt [Drug Therapy] Meta-Analysis as Topic Personality Randomized Controlled Trials as Topic 0 (Fatty Acids, Omega-3)
L1  - internal-pdf://1002938534/Ross-2007-Omega-3 fatty acids as treatments fo.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Ross, Brian M Seguin, Jennifer Sieswerda, Lee E
PY  - 2007
SP  - 21
T2  - Lipids in Health and Disease
TI  - Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid?
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17877810 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17877810&amp;id=doi:&amp;issn=1476-511X&amp;isbn=&amp;volume=6&amp;issue=&amp;spage=21&amp;pages=21&amp;date=2007&amp;title=Lipids+in+Health+%26+Disease&amp;atitle=Omega-3+fatty+acids+as+treatments+for+mental+illness%3A+which+disorder+and+which+fatty+acid%3F.&amp;aulast=Ross&amp;pid=%3Cauthor%3ERoss+BM%3C%2Fauthor%3E%3CAN%3E17877810%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071911/pdf/1476-511X-6-21.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2071911/pdf/1476-511X-6-21.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - **Background **
Cognitive-behavioral therapy (CBT) appears to be effective in the treatment of antisocial behavior both in adolescents and adults. Treatment of antisocial behavior in youth in residential settings is a challenge since it usually involves more serious behavioral problems and takes place in a closed setting. The motivation for change is usually low and there is little possibility to address the maintenance of any behavioral changes following release. 

**Objectives **
To investigate the effectiveness of CBT in reducing recidivism of adolescents placed in secure or non-secure residential settings. A secondary objective was to see if interventions that focus particularly on criminogenic needs are more effective than those with a more general focus on cognitions and behavior. Search strategy We searched a number of databases including: CENTRAL 2005 (Issue 2), MEDLINE 1966 to May 2005, Sociological Abstracts 1963 to May 2005, ERIC 1966 to November 2004, Dissertation Abstracts International 1960s to 2005. We contacted experts in the field concerning current research. 

**Selection criteria **
Both randomised controlled trials and studies with non-randomized comparison groups were included. Participants had to be young people aged 12-22 and placed in a residential setting for reasons of antisocial behavior. 

**Data collection and analysis **
Two reviewers independently reviewed 93 titles and abstracts; 35 full-text reports were retrieved and data from 12 trials eligible for inclusion were extracted and entered into RevMan. Results were synthesized using a random effects model, due to the significant heterogeneity across included studies. Results are reported at 6, 12 and 24 months post-treatment, and presented in graphical ( forest plots) form. Odds ratios are used throughout and intention-to-treat analyses were made with drop-outs imputed proportionally. Pooled estimates were weighted with inverse variance methods and 95% confidence intervals were used. 

**Main results **
The results for 12 months follow-up show that although single studies generally show no significant effects, the results for pooled data are clearly significant in favor of CBT compared to standard treatment with an odds ratio of 0,69. The reduction in recidivism is about 10% on the average. There is no evidence of effects after 6 or 24 months or when CBT is compared to alternative treatments. 

**Authors&#039; conclusions **
CBT seems to be a little more effective than standard treatment for youth in residential settings. The effects appear about one year after release, but there is no evidence of more long-term effects or that CBT is any better than alternative treatments.
AD  - Umea Univ, Dept Psychol, S-90187 Umea, Sweden. Armelius, BA (reprint author), Umea Univ, Dept Psychol, S-90187 Umea, Sweden. bengt-ake.armelius@psy.umu.se
AN  - WOS:000250188700055
AU  - Armelius,
AU  - B.
AU  - A.
AU  - Andreassen,
AU  - T.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD005650.pub2
J2  - Cochrane Database Syst Rev.
KW  - MORAL RECONATION THERAPY JUVENILE DELINQUENTS REHABILITATION PROGRAMS SERIOUS DELINQUENTS CRIMINAL RECIDIVISM RISK-FACTORS OFFENDERS METAANALYSIS INTERVENTION AGGRESSION Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 220WT Times Cited: 5 Cited Reference Count: 81 Armelius, B-A Andreassen, T. H. 5 WILEY-BLACKWELL HOBOKEN COCHRANE DB SYST REV
PY  - 2007
SP  - 37
T2  - Cochrane Database of Systematic Reviews
TI  - Cognitive-behavioral treatment for antisocial behavior in youth in residential treatment
UR  - &lt;Go to ISI&gt;://WOS:000250188700055http://onlinelibrary.wiley.com/store/10.1002/14651858.CD005650.pub2/asset/CD005650.pdf?v=1&amp;t=ib7t10a6&amp;s=20b5ee9ec14d51ec4c5ec371d307e078eff3b3da
ER  -
TY  - JOUR
AB  - **Background:** 
Some authors have suggested that loxapine is more effective than typical antipsychotics in reducing the negative symptoms of schizophrenia, that extrapyramidal adverse effects are not usually seen at clinically effective antipsychotic doses and that it should therefore be classed as atypical.

**Objectives:** 
To determine the effects of loxapine compared with placebo, typical and other atypical antipsychotic drugs for schizophrenia and related psychoses.

**Search methods:** 
For this 2007 update, we searched the Cochrane Schizophrenia Group&#039;s Register (January 2007).

**Selection criteria:** 
We included all randomised controlled clinical trials relevant to the care of schizophrenia that compared loxapine to other treatments.

**Data collection and analysis:** 
We independently inspected abstracts ordered papers, re-inspected and quality assessed these. For dichotomous data we calculated relative risks (RR) and their 95% confidence intervals (CI) on an intention-to-treat basis based on a fixed effects model. We calculated numbers needed to treat/harm (NNT/NNH) where appropriate. For continuous data, we calculated weighted mean differences (WMD) again based on a fixed effects model.

**Main results:**
We were able to include 41 studies in this review. Compared with placebo, loxapine has an antipsychotic effect (Global effect - not improved at six weeks: n=78, 2 RCTs, RR 0.30 CI 0.1 to 0.6 NNT 3 CI 3 to 5). It is as effective as typical drugs in the short term (4 -12 weeks) (Global effect: n=580, 13 RCTs, RR 0.86 CI 0.7 to 1.1; mental state: n=915, 6 RCTs, RR 0.89 CI 0.8 to 1.1). Very limited heterogeneous data suggest that, given intramuscularly (IM), loxapine may be at least as sedating as IM haloperidol and thiothixene. Loxapine is also as effective as atypicals (risperidone, quetiapine) (n=468, 6 RCTs, RR mental state not improved 1.07 CI 0.8 to 1.5). Adverse effect profile is similar to typicals but loxapine may cause more extrapyramidal adverse effects when compared with atypicals (n=340, 4 RCTs, RR 2.18 CI 1.6 to 3.1).

**Authors&#039; conclusions:** 
Loxapine is an antipsychotic which is not clearly distinct from typical or atypical drugs in terms of its effects on global or mental state. Loxapines profile of adverse effects is similar to that of the older generation of antipsychotic drugs.
AN  - CD001943
AU  - Chakrabarti,
AU  - A.
AU  - Bagnall,
AU  - A.
AU  - M.
AU  - Chue,
AU  - P.
AU  - Fenton,
AU  - M.
AU  - Palanisamy,
AU  - V.
AU  - Wong,
AU  - W.
AU  - Xia,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd001943.pub2
KW  - Antipsychotic Agents [adverse effects] [therapeutic use]
KW  - Dopamine Antagonists [adverse effects] [therapeutic use]
KW  - Loxapine [adverse effects] [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Schizophrenia [drug therapy]
KW  - Humans[checkword]
KW  - Schiz
PY  - 2007
T2  - Cochrane Database of Systematic Reviews
TI  - Loxapine for schizophrenia
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001943.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD001943.pub2/asset/CD001943.pdf?v=1&amp;t=iw7k02g1&amp;s=6528ddcca6b98f9efe4f29dbe9058e234590b9b1
ER  -
TY  - JOUR
AB  - Much research on the subject shows that cognitive-behavioural therapy effectively reduces the recidivism of offenders after serving their sentences. There is, however, a significant difference in how effective the different treatment programmes that use this form of therapy are, but further research is required to identify what sets them apart from each other. This is the question to which this Campbell review seeks an answer in its comparison of the studies of 58 different cognitive-behavioural therapy treatment programmes. 

The aim is to identify the factors that make some programmes more effective than others. 

The finding is that well-trained providers, a well-implemented course of treatment and focus on training in anger and conflict management increase the effect of the therapy. Practice is decisive- the &quot;brand name&quot; is not: The review confirms above all that cognitive-behavioural therapy is particularly effective. Of the offenders in the studies not receiving therapy, four out of ten return to criminal activity. Therapy treatment reduces the mean recidivism rate to three out of ten. But the most effective treatment reduces recidivism to two out of ten. It would appear that the differences in the courses of treatment that are of significance to effectiveness are few. According to the authors of the review, the most decisive factor is the quality, i.e. how well-implemented the programmes are, and how well-trained the providers are. This means that the most effective treatment programmes are those with a low dropout rate, where the programme is implemented according to guidelines, and where the providers have received appropriate training in cognitive-behavioural therapy. On the other hand, there is nothing to suggest that a particular type or &ldquo;brand&rdquo; of cognitive behavioural therapy used is decisive, as long as the quality is there. Apparently, it is the general therapeutic approach that has a positive effect on recidivism, and not special versions of it. Treatment settings have no bearing on the effects: The place where the treatment takes place has no measurable influence on the outcome of the treatment. It would seem that it is immaterial whether the offender is treated in prison or in the community (e.g. while on parole, on probation or in transitional aftercare). It is thus worth noting that the possibility of trying out skills learnt by the individual during therapy in domestic as opposed to institutional settings does not appear to increase the effect. The researchers also point out that there is no difference in treatment effect for juvenile offenders in institutions and adult offenders in the prison system. Important elements in the treatment: When a comparison is made of the different courses of treatment, the presence of two treatment elements is shown to increase the effect: training in anger management and training in interpersonal problem solving. There are, however, two treatment elements that have the opposite intention and reduce the effect, i.e. behaviour modification and the inclusion of victim impact. The results also show that cognitive-behavioural therapy has a greater effect on offenders with a high risk of recidivism, than those with lower risk. The review concludes overall that there are three decisive factors that influence the effect of cognitive therapeutic treatment programmes for offenders. Namely: How well the treatment is implemented, the absence or presence of certain treatment elements, and the risk of recidivism of the offenders participating. 

Facts about the review: This review includes 58 studies of treatment programmes. All are based on randomised controlled trials or other trials that compare groups which have participated in the treatment with a control group. The majority of the studies measure the effect of cognitive-behavioural therapy on recidivism a year after the treatment. The studies are from the US, Canada, UK and New Zealand and were published between 1980 and 2004. The treatment programmes studied all consisted of structured therapy sessions, most lasti g le s than 20 weeks. Approximately half of the programmes were implemented at the institution where the offender was serving his/her sentence, the other half in the community in connection with probation, parole or transitional aftercare. The providers in charge of the treatment had mixed backgrounds, but some had little or no professional experience within psychology and had received relatively little training in cognitive-behavioural therapy. Recommendations for future research The authors of this review emphasise that almost half of the studies included are based on treatment on a trial basis. Further studies are therefore required before it can be confirmed whether the effect remains as positive once the treatment has become routine practice. The authors do not, however, believe there to be any reason to doubt the results of the review.
AU  - Lipsey,
AU  - M.
AU  - Landenberger,
AU  - N.
AU  - A.
AU  - Wilson,
AU  - S.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2007.6
KW  - Behaviour therapy
KW  - Offenders
KW  - Crime
PY  - 2007
T2  - Campbell Systematic Reviews
TI  - Effects of Cognitive-Behavioral Programs for Criminal Offenders: A Systematic Review
ER  -
TY  - JOUR
AB  - The aim of the present paper was to critically examine evidence about the benefits of cognitive-behavioural therapy (CBT) for pediatric obsessive-compulsive disorder (OCD) from controlled and single group studies, including its benefits relative to medication are critically reviewed. 

Selected studies were categorized by study type and by risk of bias classification. Standardized mean differences (Hedges&#039; g or Cohen d) and, where appropriate, weighted mean difference (WMD) were calculated. All five comparison and 14 one-group studies showed a significant benefit for CBT within a wide range (ES = .78 to 4.38). Low risk of bias studies produced the lower adjusted effect sizes. 

The best available estimate of CBT efficacy relative to no treatment is about 1 standardized mean difference, equivalent to a treatment effect of 8 points on the Children&#039;s Yale-Brown Obsessive-Compulsive Scale. This represents a reduction in the risk of continuing to have OCD post-treatment of about 37% (95% Cl 14% to 54%). 

Evidence from 3 studies indicates that the efficacy of CBT and medication do not differ significantly. CBT combined with medication is significantly more efficacious than non-active controls or medication alone but not relative to CBT alone. CBT should be regarded as a first line equivalent to anti-OCD medication with the potential to lead to better outcomes when combined with medication than medication alone can provide. 

Additional studies are needed to further clarify CBT&#039;s benefits and to investigate how it can be made more available as a treatment option for children and youth who suffer from OCD.
AD  - Australian Natl Univ, Sch Psychol, Canberra, ACT 0200, Australia. O&#039;Kearney, R (reprint author), Australian Natl Univ, Sch Psychol, Canberra, ACT 0200, Australia. richard.okearney@anu.edu.au
AN  - WOS:000245676900001
AU  - O&#039;
AU  - Kearney,
AU  - R.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/00048670601172707
J2  - Aust. N. Z. J. Psych.
KW  - children and youth cognitive-behavioural therapy meta-analysis obsessive -compulsive disorder treatment evaluation CONTROLLED-TRIAL RESPONSE PREVENTION FAMILY TREATMENT ADOLESCENTS CHILDHOOD METAANALYSIS PSYCHOTHERAPY BASE OCD SERTRALINE Psychiatry
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 156VB Times Cited: 3 Cited Reference Count: 58 O&#039;Kearney, Richard 4 INFORMA HEALTHCARE-TAYLOR &amp; FRANCIS ABINGDON AUST NZ J PSYCHIAT
PY  - 2007
SP  - 199-212
T2  - Australian and New Zealand Journal of Psychiatry
TI  - Benefits of cognitive-behavioural therapy for children and youth with obsessive-compulsive disorder: re-examination of the evidence
UR  - &lt;Go to ISI&gt;://WOS:000245676900001http://anp.sagepub.com/content/41/3/199http://anp.sagepub.com/content/41/3/199.full.pdf
VL  - 41
ER  -
TY  - JOUR
AB  - A review of studies published between 1980 and 2005 shows a significant positive effect of specialized training on the competency of caregivers in childcare (d = 0.45, S.E. = 0.10). Experimental results from the meta-analysis were significantly smaller for settings with no fixed curriculum content, delivery of the training at multiple sites and large-scale programs. Results were also smaller when tests were used that did not align closely with the content of the training. Furthermore, experimental results were smaller for the skills domain, compared to the knowledge and attitude domain. A subset of experiments with both caregiver and child data also showed a positive effect, supporting the causal link between caregiver training, caregiver competencies and child behavior in childcare, although this effect was not significant due to the small number of studies (d = 0.55, S.E. = 0.30). Based on these findings, we advocate the inclusion of instruction related to teacher-child interaction in the curriculum of vocational training for caregivers. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Fukkink, Ruben G.: r.g.fukkink@uva.nl Fukkink, Ruben G.: SCO-Kohnstamm Instituut, Universiteit van Amsterdam, Wibautstraat 2-4, Amsterdam, Netherlands, 1091 GM, r.g.fukkink@uva.nl Fukkink, Ruben G.: SCO-Kohnstamm Instituut, Universiteit van Amsterdam, Amsterdam, Netherlands Lont, Anna: SCO-Kohnstamm Instituut, Universiteit van Amsterdam, Amsterdam, Netherlands
AN  - 2007-12920-002
AU  - Fukkink,
AU  - R.
AU  - G.
AU  - Lont,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.ecresq.2007.04.005
DP  - Ovid Technologies
KW  - caregivers, childcare, vocational training, competency, teacher-child interaction *Caregivers *Child Care *Professional Competence *Training *Vocational Education Teacher Student Interaction Educational Administration &amp; Personnel [3510] Human
LA  - English
M3  - Meta Analysis
PY  - 2007
SP  - 294-311
T2  - Early Childhood Research Quarterly
TI  - Does training matter? A meta-analysis and review of caregiver training studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc5&amp;AN=2007-12920-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.ecresq.2007.04.005&amp;issn=0885-2006&amp;isbn=&amp;volume=22&amp;issue=3&amp;spage=294&amp;pages=294-311&amp;date=2007&amp;title=Early+Childhood+Research+Quarterly&amp;atitle=Does+training+matter%3F+A+meta-analysis+and+review+of+caregiver+training+studies.&amp;aulast=Fukkink&amp;pid=%3Cauthor%3EFukkink%2C+Ruben+G%3C%2Fauthor%3E%3CAN%3E2007-12920-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0885200607000336/1-s2.0-S0885200607000336-main.pdf?_tid=34154c9a-18da-11e5-b4f2-00000aacb35e&amp;acdnat=1434976296_25e48ae6ba1ffd15b199ade160ed6b62
VL  - 22
ER  -
TY  - JOUR
AB  - **Background:** 
Postnatal depression has detrimental effects on the child&#039;s cognitive and emotional development. 

**Aims:** 
To assess the benefits of treating postnatal depression for mother-infant interaction and child development. 

**Method:** 
A systematic search was made of 12 electronic bibliographic databases for randomised controlled trials and controlled clinical trials on treatment of mothers with postnatal depression, where outcomes were assessed in assessed in children; findings were assessed. 

**Results:** 
Only eight trials met the inclusion criteria. Of those included, interventions varied widely but all involved therapies directed at the mother-infant relationship. One study with intensive and prolonged therapy showed cognitive improvement, where as two others with briefer interventions improved maternal-infant relationships but did not affect the child&#039;s cognitive or behavioural development. All five studies assessing only mother-infant relationships showed improvements. 

**Conclusions:** 
Cognitive development in children of depressed mothers, along with better mother-infant relationships, might be improved with sustained interventions. Trials assessing treatments for postnatal depression would benefit from looking more closely at benefits for children as well as mothers, using validated children as well objective measures. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - S C. s J H. g Poobalan, A. S.: a.poobalan@abdn.ac.uk Poobalan, A. S.: Department of Public Health, Medical School, Polwarth Building, Foresterhill, Aberdeen, United Kingdom, AB25 2ZD, a.poobalan@abdn.ac.uk Poobalan, A. S.: Scottish Evidence Based Child Health Unit, Department of Child Health, University of Aberdeen, Aberdeen, United Kingdom Aucott, L. S.: Department of Public Health, University of Aberdeen, Aberdeen, United Kingdom Ross, L.: Scottish Evidence Based Child Health Unit, Departmentof Child Health, University of Aberdeen, Aberdeen, United Kingdom Smith, W.C. S.: Department of Public Health, University of Aberdeen, Aberdeen, United Kingdom Helms, P. J.: Department of Child Health, University of Aberdeen, Aberdeen, United Kingdom Williams, J. H. G.: Department of Child Health, University of Aberdeen, Aberdeen, United Kingdom
AN  - 2008-11368-005
AU  - Poobalan,
AU  - A.
AU  - Aucott,
AU  - L.
AU  - Ross,
AU  - L.
AU  - Smith,
AU  - W.
AU  - Helms,
AU  - P.
AU  - Williams,
AU  - J.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1192/bjp.bp.106.032789
DP  - Ovid Technologies
KW  - postnatal depression, mother-infant interaction development, emotional development, child development, treatment *Cognitive Development *Emotional Development *Mother Child Relations *Postpartum Depression *Treatment Infant Development Affective Disorde
L1  - internal-pdf://3405919283/Poobalan-2007-Effects of treating postnatal de.pdf
LA  - English
M3  - Literature Review; Systematic Review
PY  - 2007
SP  - 378-386
T2  - The British Journal of Psychiatry
TI  - Effects of treating postnatal depression on mother-infant interaction and child development: Systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc5&amp;AN=2008-11368-005 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1192%2Fbjp.bp.106.032789&amp;issn=0007-1250&amp;isbn=&amp;volume=191&amp;issue=5&amp;spage=378&amp;pages=378-386&amp;date=2007&amp;title=The+British+Journal+of+Psychiatry&amp;atitle=Effects+of+treating+postnatal+depression+on+mother-infant+interaction+and+child+development%3A+Systematic+review.&amp;aulast=Poobalan&amp;pid=%3Cauthor%3EPoobalan%2C+A.+S%3C%2Fauthor%3E%3CAN%3E2008-11368-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://bjp.rcpsych.org/content/bjprcpsych/191/5/378.full.pdf
UR  - http://bjp.rcpsych.org/content/bjprcpsych/191/5/378.full.pdf
VL  - 191
ER  -
TY  - JOUR
AB  - **Objective:** 
To review weight and metabolic effects of mood-stabilizing treatments in pediatric bipolar disorder. 

**Method:** 
Systematic PubMed/fidedfine search of studies reporting on change in weight and/or glucose/lipid values with mood-stabilizing drugs in at least nine pediatric patients with bipolar disorder. 

**Results:** 
Nineteen studies, including 24 medication trials in 684 patients (mean age, 12.3 +/- 2.9 years) were included. Youngsters received lithium, antiepileptics, or their combinations (n = 459), or second-generation antipsychotics, alone or combined with lithium or divalproex (n = 225), for 4 to 48 (mean, 15.4 +/- 12.7) weeks. Weight increase was significant/clinically relevant in 18 (75.0%) trials. Weight loss was significant with topiramate (2 studies, 38 subjects) and present with aripiprazole (1 study, 14 subjects). In trials lasting &lt;= 12 weeks, weight gain was greater with second-generation antipsychotics plus mood stabilizers (5.5 +/- 1.8 kg) compared to mood-stabilizer monotherapy (1.2 +/- 1.9 kg, p &lt; .05, Cohen&#039;s d = 2.33) or mood-stabilizer cotreatment (2.1 +/- 1.3 kg, p &lt; .05, Cohen&#039;s d = 2.17), but not compared to antipsychotic monotherapy (3.4 +/- 1.3 kg, p &gt; .05, Cohen&#039;s d = 1.34). Nonfasting glucose/lipid changes were nonsignificant in two second-generation antipsychotic trials (n = 61, 8.9%). 

**Conclusions:** 
Data are sparse regarding body composition effects and lacking for fasting metabolic effects of mood stabilizers in pediatric bipolar disorder. Combining antipsychotics with mood stabilizers seems to lead to greater weight gain than treatment with one or two mood stabilizers.
AD  - Zucker Hillside Hosp, N Shore Long Isl Jewish Hlth Syst, Glen Oaks, NY 11004 USA. Albert Einstein Coll Med, Bronx, NY 10467 USA. Correll, CU (reprint author), Zucker Hillside Hosp, N Shore Long Isl Jewish Hlth Syst, Glen Oaks, NY 11004 USA. ccorrell@lij.edu
AN  - WOS:000246733900003
AU  - Correll,
AU  - C.
AU  - U.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1097/chi.0b013e318040b25f
J2  - J. Am. Acad. Child Adolesc. Psychiatr.
KW  - bipolar disorder second-gene ration antipsychotics mood stabilizers weight gain metabolic abnormalities CARDIOVASCULAR RISK-FACTORS INTIMA-MEDIA THICKNESS BODY-MASS INDEX PLACEBO-CONTROLLED TRIAL OPEN-LABEL TRIAL DOUBLE-BLIND ATYPICAL ANTIPSYCHOTICS DIV
L1  - internal-pdf://1260819345/Correll-2007-Weight gain and metabolic effects.pdf
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 171KD Times Cited: 81 Cited Reference Count: 64 Correll, Christoph U. Correll, Christoph/D-3530-2011 81 LIPPINCOTT WILLIAMS &amp; WILKINS PHILADELPHIA J AM ACAD CHILD PSY
PY  - 2007
SP  - 687-700
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Weight gain and metabolic effects of mood stabilizers and antipsychotics in pediatric bipolar disorder: A systematic review and pooled analysis of short-term trials
UR  - &lt;Go to ISI&gt;://WOS:000246733900003http://ac.els-cdn.com/S0890856709621481/1-s2.0-S0890856709621481-main.pdf?_tid=298034ce-1674-11e5-ba05-00000aacb35d&amp;acdnat=1434712567_80e62b85c0b92d18f5c04bed033eacb0
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCDCKGDIMI00/fs046/ovft/live/gv023/00004583/00004583-200706000-00003.pdf
VL  - 46
ER  -
TY  - JOUR
AB  - **Background:** 
Mother and baby units (MBUs) are recommended, in the UK, as an optimal site for treating post partum psychoses. Naturalistic studies suggest poor outcomes for mothers and their children if admission is needed during the first year after birth, but the evidence for the effectiveness of MBUs in addressing the problems faced by both mothers with mental illness and their babies is unclear.

**Objectives:** 
To review the effects of mother and baby units for mothers with schizophrenia or psychoses needing admission during the first year after giving birth, and their children, in comparison to standard care on a ward without a mother and baby unit.

**Search methods:** 
We undertook electronic searches of the Cochrane Schizophrenia Group&#039;s Register (June 2006).

**Selection criteria:** 
We included all randomised clinical trials comparing placement on a mother and baby unit compared to any other standard care without attachment to such a unit.

**Data collection and analysis:** 
If data were available we would have independently extracted data and analysed on an intention-to treat basis; calculated the relative risk (RR) and 95% confidence intervals (CI) of homogeneous dichotomous data using a random effects model, and where possible calculated the number needed to treat (NNT); calculated weighted mean differences (WMD) for continuous data.

**Main results:**
Unfortunately, we did not find any relevant studies to include. One non-randomised trial, published in 1961, suggested beneficial effects for those admitted to mother and baby units. For the experimental group, more women were able to care for their baby on their own and experienced fewer early relapses on their return home compared with standard care. Care practices for people with schizophrenia have changed dramatically over the past 40 years and a sensitively designed pragmatic trial is possible and justified.

**Authors&#039; conclusions:** 
Mother and bay units are reportedly common in the UK but less common in other countries and rare or non-existent in the developing world. However, there does not appear to be any trial-based evidence for the effectiveness of these units. This lack of data is of concern as descriptive studies have found poor outcomes such as anxious attachment and poor development for children of mothers with schizophrenia and a greater risk of the children being placed under supervised or foster care. Effective care of both mothers and babies during this critical time may be crucial to prevent poor clinical and parenting outcomes. Good, relevant research is urgently needed.
AN  - CD006333
AU  - Irving,
AU  - C.
AU  - B.
AU  - Saylan,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd006333
KW  - Child of Impaired Parents
KW  - Hospitalization
KW  - Maternal-Child Health Centers
KW  - Infant, Newborn
KW  - Psychotic Disorders [therapy]
KW  - Puerperal Disorders [therapy]
KW  - Schizophrenia [therapy]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Infant[checkword]
KW  - Schiz
PY  - 2007
T2  - Cochrane Database of Systematic Reviews
TI  - Mother and baby units for schizophrenia
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006333/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006333/asset/CD006333.pdf?v=1&amp;t=iw7k92p3&amp;s=4e58bbb9287ccc5de5c3b5073405df1e09425d6e
ER  -
TY  - JOUR
AB  - **CONTEXT: **
The US Food and Drug Administration (FDA) has issued warnings that use of antidepressant medications poses a small but significantly increased risk of suicidal ideation/suicide attempt for children and adolescents. 

**OBJECTIVE: **
To assess the efficacy and risk of reported suicidal ideation/suicide attempt of antidepressants for treatment of pediatric major depressive disorder (MDD), obsessive-compulsive disorder (OCD), and non-OCD anxiety disorders. 

**DATA SOURCES AND STUDY SELECTION: **
PubMed (1988 to July 2006), relevant US and British regulatory agency reports, published abstracts of important scientific meetings (1998-2006), clinical trial registries, and information from authors. Studies were published and unpublished randomized, placebo-controlled, parallel-group trials of second-generation antidepressants (selective serotonin reuptake inhibitors, nefazodone, venlafaxine, and mirtazapine) in participants younger than 19 years with MDD, OCD, or non-OCD anxiety disorders. 

**DATA EXTRACTION:** 
Information was extracted on study characteristics, efficacy outcomes, and spontaneously reported suicidal ideation/suicide attempt. 

DATA SYNTHESIS: 
Twenty-seven trials of pediatric MDD (n = 15), OCD (n = 6), and non-OCD anxiety disorders (n = 6) were selected, and risk differences for response and for suicidal ideation/suicide attempt estimated by random-effects methods. Pooled risk differences in rates of primary study-defined measures of responder status significantly favored antidepressants for MDD (11.0%; [95% confidence interval {CI}, 7.1% to 14.9%]), OCD (19.8% [95% CI, 13.0% to 26.6%), and non-OCD anxiety disorders (37.1% [22.5% to 51.7%]), corresponding to a number needed to treat (NNT) of 10 (95% CI, 7 to 15), 6 (4 to 8), and 3 (2 to 5), respectively. While there was increased risk difference of suicidal ideation/suicide attempt across all trials and indications for drug vs placebo (0.7%; 95% CI, 0.1% to 1.3%) (number needed to harm, 143 [95% CI, 77 to 1000]), the pooled risk differences within each indication were not statistically significant: 0.9% (95% CI, -0.1% to 1.9%) for MDD, 0.5% (-1.2% to 2.2%) for OCD, and 0.7% (-0.4% to 1.8%) for non-OCD anxiety disorders. 

There were no completed suicides. Age-stratified analyses showed that for children younger than 12 years with MDD, only fluoxetine showed benefit over placebo. In MDD trials, efficacy was moderated by age, duration of depression, and number of sites in the treatment trial. 

**CONCLUSIONS: **
Relative to placebo, antidepressants are efficacious for pediatric MDD, OCD, and non-OCD anxiety disorders, although the effects are strongest in non-OCD anxiety disorders, intermediate in OCD, and more modest in MDD. Benefits of antidepressants appear to be much greater than risks from suicidal ideation/suicide attempt across indications, although comparison of benefit to risk varies as a function of indication, age, chronicity, and study conditions.
AD  - Bridge,Jeffrey A. Department of Pediatrics and Columbus Children&#039;s Research Institute, The Ohio State University, Columbus, USA.
AN  - 17440145
AU  - Bridge,
AU  - J.
AU  - A.
AU  - Iyengar,
AU  - S.
AU  - Salary,
AU  - C.
AU  - B.
AU  - Barbe,
AU  - R.
AU  - P.
AU  - Birmaher,
AU  - B.
AU  - Pincus,
AU  - H.
AU  - A.
AU  - Ren,
AU  - L.
AU  - Brent,
AU  - D.
AU  - A.
DA  - Apr 18
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1001/jama.297.15.1683
DP  - Ovid Technologies
J2  - Jama
KW  - Adolescent Antidepressive Agents, Second-Generation/ae [Adverse Effects] *Antidepressive Agents, Second-Generation/tu [Therapeutic Use] *Anxiety Disorders/dt [Drug Therapy] Child *Depressive Disorder, Major/dt [Drug Therapy] Humans *Obsessive-Compulsive
L1  - internal-pdf://1340671677/Bridge-2007-Clinical response and risk for rep.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov&#039;t
N1  - Bridge, Jeffrey A Iyengar, Satish Salary, Cheryl B Barbe, Remy P Birmaher, Boris Pincus, Harold Alan Ren, Lulu Brent, David A Comment in: JAMA. 2007 Aug 8;298(6):626; author reply 627; PMID: 17684184 Comment in: Evid Based Ment Health. 2007 Nov;10(4):108; PMID: 17962653 Comment in: JAMA. 2007 Aug 8;298(6):626-7; author reply 627; PMID: 17684183 1UL1RR024156-01 (United States NCRR NIH HHS) K01-MH069948 (United States NIMH NIH HHS) P30-MH066371 (United States NIMH NIH HHS)
PY  - 2007
SP  - 1683-96
T2  - JAMA
TI  - Clinical response and risk for reported suicidal ideation and suicide attempts in pediatric antidepressant treatment: a meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17440145
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17440145&amp;id=doi:&amp;issn=0098-7484&amp;isbn=&amp;volume=297&amp;issue=15&amp;spage=1683&amp;pages=1683-96&amp;date=2007&amp;title=JAMA&amp;atitle=Clinical+response+and+risk+for+reported+suicidal+ideation+and+suicide+attempts+in+pediatric+antidepressant+treatment%3A+a+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Bridge&amp;pid=%3Cauthor%3EBridge+JA%3C%2Fauthor%3E%3CAN%3E17440145%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://jama.jamanetwork.com/data/Journals/JAMA/5143/jrv70005_1683_1696.pdf
UR  - https://jamanetwork.com/journals/jama/articlepdf/206656/jrv70005_1683_1696.pdf
VL  - 297
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
With almost a million people dying by suicide worldwide each year, reducing the rate of suicidal behaviour is a priority in many countries.AIMS: To examine whether additional psychosocial interventions following an episode of self-harm reduce the likelihood of subsequent suicide.

**METHOD: **
We conducted a systematic review and meta-analysis of data from randomised controlled trials of interventions for people following self-harm. Likelihood of suicide was compared by calculating the pooled root difference in suicide rate with 95% confidence intervals.

**RESULTS: **
We obtained suicide data from 18 studies with a total population of 3918. Eighteen suicides occurred among people offered active treatment and 19 among those offered standard care (pooled root difference in suicide rate 0.0,95% CI -0.03 to 0.03). The overall rate of suicide among people participating in trials was similar to that reported in observational studies of people who self-harm.

**CONCLUSIONS: **
Results of this meta-analysis do not provide evidence that additional psychosocial interventions following self-harm have a marked effect on the likelihood of subsequent suicide.
AD  - Crawford, Mike J. Faculty of Medicine, Imperial College London, UK. m.crawford@imperial.ac.uk
AN  - 17197651
AU  - Crawford,
AU  - M.
AU  - J.
AU  - Thomas,
AU  - O.
AU  - Khan,
AU  - N.
AU  - Kulinskaya,
AU  - E.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1192/bjp.bp.106.025437
DP  - Ovid Technologies
J2  - Br J Psychiatry
KW  - Adolescent
KW  - Adult
KW  - Humans
KW  - Meta-Analysis as Topic
KW  - *Psychotherapy/mt [Methods]
KW  - Risk Factors
KW  - *Suicide/pc [Prevention &amp; Control]
KW  - Suicide/sn [Statistics &amp; Numerical Data]
L1  - internal-pdf://2358641891/Crawford-2007-Psychosocial interventions follo.pdf
LA  - English
M3  - Meta-Analysis
Research Support, Non-U.S. Gov&#039;t
Review
N1  - Crawford, Mike JThomas, OliviaKhan, NusratKulinskaya, ElenaComment in: Br J Psychiatry. 2007 Oct;191:359-60; author reply 360; PMID: 17906253
PY  - 2007
SP  - 11-7
T2  - British Journal of Psychiatry
TI  - Psychosocial interventions following self-harm: systematic review of their efficacy in preventing suicide
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=17197651
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17197651&amp;id=doi:10.1192%2Fbjp.bp.106.025437&amp;issn=0007-1250&amp;isbn=&amp;volume=190&amp;issue=1&amp;spage=11&amp;pages=11-7&amp;date=2007&amp;title=British+Journal+of+Psychiatry&amp;atitle=Psychosocial+interventions+following+self-harm%3A+systematic+review+of+their+efficacy+in+preventing+suicide.&amp;aulast=Crawford&amp;pid=%3Cauthor%3ECrawford+MJ%3C%2Fauthor%3E%3CAN%3E17197651%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/5874892F316A95BFB4306F6F00E3A957/S0007125000233229a.pdf/div-class-title-psychosocial-interventions-following-self-harm-div.pdf
VL  - 190
ER  -
TY  - JOUR
AB  - Obsessive-compulsive disorder (OCD) is a distressing and functionally impairing disorder that can emerge as early as age 4. Cognitive behavior therapy (CBT) for OCD in youth shows great promise for amelioration of symptoms and associated functional impairment. 

However, the empirical evidence base for the efficacy of CBT in youth has some significant limitations, particularly as related to treating the very young child with OCD. This report includes a quantitative review of existing child CBT studies to evaluate evidence for the efficacy of CBT for OCD. It identifies gaps in the literature that, when addressed, would enhance the understanding of effective treatment in pediatric OCD. 

Finally, it presents a proposed research agenda for addressing the unique concerns of the young child with OCD.
AD  - Freeman,Jennifer B. Bradley/Hasbro Research Center, Brown Medical School, Providence, Rhode Island 02903, USA. jfreeman@lifespan.org
AN  - 17241829
AU  - Freeman,
AU  - J.
AU  - B.
AU  - Choate-Summers,
AU  - M.
AU  - L.
AU  - Moore,
AU  - P.
AU  - S.
AU  - Garcia,
AU  - A.
AU  - M.
AU  - Sapyta,
AU  - J.
AU  - J.
AU  - Leonard,
AU  - H.
AU  - L.
AU  - Franklin,
AU  - M.
AU  - E.
DA  - Feb 1
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.biopsych.2006.12.015
DP  - Ovid Technologies
J2  - Biol Psychiatry
KW  - Adolescent Child *Cognitive Therapy Humans Obsessive-Compulsive Disorder/px [Psychology] *Obsessive-Compulsive Disorder/th [Therapy] Research Design
L1  - internal-pdf://3737507139/Freeman-2007-Cognitive behavioral treatment fo.pdf
LA  - English
M3  - Research Support, N.I.H., Extramural Review
N1  - Freeman, Jennifer B Choate-Summers, Molly L Moore, Phoebe S Garcia, Abbe M Sapyta, Jeffrey J Leonard, Henrietta L Franklin, Martin E R21 MH060669-03 (United States NIMH NIH HHS) R21MH60669 (United States NIMH NIH HHS)
PY  - 2007
SP  - 337-43
T2  - Biological Psychiatry
TI  - Cognitive behavioral treatment for young children with obsessive-compulsive disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17241829 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17241829&amp;id=doi:&amp;issn=0006-3223&amp;isbn=&amp;volume=61&amp;issue=3&amp;spage=337&amp;pages=337-43&amp;date=2007&amp;title=Biological+Psychiatry&amp;atitle=Cognitive+behavioral+treatment+for+young+children+with+obsessive-compulsive+disorder.&amp;aulast=Freeman&amp;pid=%3Cauthor%3EFreeman+JB%3C%2Fauthor%3E%3CAN%3E17241829%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0006322306015691/1-s2.0-S0006322306015691-main.pdf?_tid=449fe7f6-18b6-11e5-88fe-00000aab0f6b&amp;acdnat=1434960862_cc343816370bd2f40d57b44701c41564
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894755/pdf/nihms17016.pdf
VL  - 61
ER  -
TY  - JOUR
AB  - **Background:** 
Although pregnancy was once thought of as a time of emotional wellbeing for many women, conferring &#039;protection&#039; against psychiatric disorders, a recent meta-analysis of 21 studies suggests the mean prevalence rate for depression across the antenatal period is 10.7%, ranging from 7.4% in the first trimester to a high of 12.8% in the second trimester. Due to maternal treatment preferences and potential concerns about fetal and infant health outcomes, non-pharmacological treatment options are needed.

**Objectives:** 
The primary objective of this review is to assess the effects, on mothers and their families, of psychosocial and psychological interventions compared with usual antepartum care in the treatment of antenatal depression.

**Search methods:** 
We searched the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register (September 2006), the Cochrane Collaboration Depression Anxiety and Neurosis Group&#039;s Trials Registers (CCDANCTR-Studies and CCDANCTR-References) (July 2006), the Cochrane Central Register of Controlled Trials (The Cochrane Library 2006, Issue 3), MEDLINE (1966 to July 2006), EMBASE (1980 to July 2006) and CINAHL (1982 to July 2006). We also scanned secondary references and contacted experts in the field to identify other published or unpublished trials.We updated the search of the Cochrane Pregnancy and Childbirth Group&#039;s Trials Register on 31 March 2010 and added the results to the awaiting classification section.

**Selection criteria:** 
All published, unpublished and ongoing randomised controlled trials of preventive psychosocial or psychological interventions in which the primary or secondary aim is to treat antenatal depression. We excluded quasi-randomised trials (for example, those randomised by delivery date, or odd versus even medical record numbers) from the analysis.

**Data collection and analysis:** 
All review authors participated in the evaluation of methodological quality and data extraction. Results are presented using relative risk for categorical data and weighted mean difference for continuous data.

**Main results:** 
One US trial was included in this review, incorporating 38 outpatient antenatal women who met Diagnostic and Statistical Manual for Mental Disorders-IV criteria for major depression. Interpersonal psychotherapy, compared to a parenting education program, was associated with a reduction in the risk of depressive symptomatology immediately post-treatment using the Clinical Global Impression Scale (one trial, n = 38; relative risk (RR) 0.46, 95% confidence interval (CI) 0.26 to 0.83) and the Hamilton Rating Scale for Depression (one trial, n = 38; RR 0.82, 95% CI 0.65 to 1.03).

**Authors&#039; conclusions:** 
The evidence is inconclusive to allow us to make any recommendations for interpersonal psychotherapy for the treatment of antenatal depression. The one trial included was too small, with a non-generalisable sample, to make any recommendations.[Note: The 12 citations in the awaiting classification section of the review may alter the conclusions of the review once assessed.]
AN  - CD006309
AU  - Dennis,
AU  - C.
AU  - L.
AU  - Ross,
AU  - L.
AU  - E.
AU  - Grigoriadis,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd006309
KW  - Parenting
KW  - Psychotherapy
KW  - Depression [therapy]
KW  - Pregnancy Complications [psychology] [therapy]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Pregnancy[checkword]
KW  - Preg
PY  - 2007
T2  - Cochrane Database of Systematic Reviews
TI  - Psychosocial and psychological interventions for treating antenatal depression
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006309.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD006309.pub2/asset/CD006309.pdf?v=1&amp;t=iw7kvng7&amp;s=d7529154cc66e1950c8d0b95ca8127ed119e69a6
ER  -
TY  - JOUR
AB  - The commonalities between anxiety and depression have been discussed before, but few have delineated the potentially different mechanisms through which treatments work for these populations. 

The current study conducted a comprehensive review of child and adolescent randomized clinical trials that tested cognitive-behavioral therapy (CBT) for anxiety or depression. 

All studies were required to have assessed both treatment outcomes and at least one theory-specific process target, including behavioral, physiological, cognitive, and coping variables. Using a meta-analytic approach, CBT demonstrated positive treatment gains across anxiety, depression, and general functioning outcomes. CBT for anxiety also produced moderate to large effects across behavioral, physiological, cognitive, and coping processes, with behavioral targets demonstrating potentially the greatest change. CBT for depression produced small effects for cognitive processes but nonsignificant effects for behavioral and coping variables. 

Findings were generally consistent with CB theory but suggest potentially different mediators in the treatment of anxiety and depression. Results are discussed in terms of implications for mechanisms research, theories of change, and treatment development.
AD  - Chu,Brian C. Department of Psychology, Rutgers, The State University of New Jersey, 152 Frelinghuysen Road, Piscataway, NJ 08854, USA. BrianChu@rci.Rutgers.edu
AN  - 17985239
AU  - Chu,
AU  - B.
AU  - C.
AU  - Harrison,
AU  - T.
AU  - L.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s10567-007-0028-2
DP  - Ovid Technologies
J2  - Clin Child Fam Psychol Rev
KW  - Adolescent *Anxiety Disorders/th [Therapy] Child *Cognitive Therapy/mt [Methods] *Depressive Disorder/th [Therapy] Humans
LA  - English
M3  - Meta-Analysis
N1  - Chu, Brian C Harrison, Tara L
PY  - 2007
SP  - 352-72
T2  - Clinical Child and Family Psychology Review
TI  - Disorder-specific effects of CBT for anxious and depressed youth: a meta-analysis of candidate mediators of change
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17985239 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17985239&amp;id=doi:&amp;issn=1096-4037&amp;isbn=&amp;volume=10&amp;issue=4&amp;spage=352&amp;pages=352-72&amp;date=2007&amp;title=Clinical+Child+%26+Family+Psychology+Review&amp;atitle=Disorder-specific+effects+of+CBT+for+anxious+and+depressed+youth%3A+a+meta-analysis+of+candidate+mediators+of+change.&amp;aulast=Chu&amp;pid=%3Cauthor%3EChu+BC%3C%2Fauthor%3E%3CAN%3E17985239%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10567-007-0028-2
VL  - 10
ER  -
TY  - JOUR
AB  - The existing reviews of massage therapy (MT) research are either limited to infants, adults, or were conducted prior to the publication of the most recent studies using pediatric samples. Randomized controlled trials (RCTs) of pediatric MT are reviewed. A literature search yielded 24 RCTs of pediatric MT, defined as the manual manipulation of soft tissue intended to promote health and well-being in recipients between 2 and 19 years of age. Because RCTs of pediatric MT varied considerably in the amount and types of data reported, quantitative and narrative review methods were both used. Single-dose and multiple-dose effects were examined separately. Among single-dose effects, significant reductions of state anxiety were observed at the first session (g = 0.59, P &lt; 0.05) and the last session (g = 1.10, P &lt; 0.01) of a course of treatment. Effects for salivary cortisol (g = 0.28), negative mood (g = 0.52) and behavior (g = 0.37) were non-significant. Three of eleven multiple-dose effects were statistically significant. These were trait anxiety (g = 0.94, P &lt; 0.05), muscle tone (g = 0.90, P &lt; 0.01) and arthritis pain (g = 1.33, P &lt; 0.01). Results of studies not permitting effect size calculation were judged to be generally consistent with quantitative results. MT benefits pediatric recipients, though not as universally as sometimes reported. Numerous weaknesses endemic to MT research (e.g. low statistical power, frequent failure to report basic descriptive statistics) are identified, and recommendations for future pediatric MT research are discussed.
AD  - Beider, Shay. Integrative Touch for Kids, Beverly Hills CA and University of Illinois at Urbana-Champaign, Urbana IL 61801-4819, USA.
AN  - 17342238
AU  - Beider,
AU  - S.
AU  - Moyer,
AU  - C.
AU  - A.
DA  - Mar
DB  - Alle inkluderte systematiske oversikter i IN SUM.enl
DO  - 10.1093/ecam/nel068
DP  - Ovid Technologies
J2  - Evid Based Complement Alternat Med
L1  - internal-pdf://1023217730/Beider.pdf
LA  - English
N1  - Beider, ShayMoyer, Christopher A
PY  - 2007
SP  - 23-34
T2  - Evidence-Based Complementary &amp; Alternative Medicine: eCAM
TI  - Randomized controlled trials of pediatric massage: a review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=prem1&amp;AN=17342238
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17342238&amp;id=doi:10.1093%2Fecam%2Fnel068&amp;issn=1741-427X&amp;isbn=&amp;volume=4&amp;issue=1&amp;spage=23&amp;pages=23-34&amp;date=2007&amp;title=Evidence-Based+Complementary+%26+Alternative+Medicine%3A+eCAM&amp;atitle=Randomized+controlled+trials+of+pediatric+massage%3A+a+review.&amp;aulast=Beider&amp;pid=%3Cauthor%3EBeider+S%3C%2Fauthor%3E%3CAN%3E17342238%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 4
ER  -
TY  - JOUR
AB  - **Background **
Early malnutrition and/or micronutrient deficiencies can adversely affect physical, mental, and social aspects of child health. School feeding programs are designed to improve attendance, achievement, growth, and other health outcomes. 

**Objectives **
The main objective was to determine the effectiveness of school feeding programs in improving physical and psychosocial health for disadvantaged school children. Search strategy We searched a number of databases including CENTRAL (2006 Issue 2), MEDLINE ( 1966 to May 2006), EMBASE (1980 to May 2006), PsycINFO (1980 to May 2006) and CINAHL (1982 to May 2006). Grey literature sources were also searched. Reference lists of included studies and key journals were handsearched and we also contacted selected experts in the field. 

**Selection criteria **
Data from randomized controlled trials (RCTs), non-randomised controlled clinical trials (CCTs), controlled before and after studies (CBAs), and interrupted time series studies (ITSs) were included. Feeding had to be done in school; the majority of participants had to be socio-economically disadvantaged. 

**Data collection and analysis **
Two reviewers assessed all searches and retrieved studies. Data extraction was done by one of four reviewers and reviewed by a second. Two reviewers independently rated quality. If sufficient data were available, they were synthesized using random effects meta-analysis, adjusting for clustering if needed. Analyses were performed separately for RCTs and CBAs and for higher and lower income countries. 

**Main results **
We included 18 studies. For weight, in the RCTs and CBAs from Lower Income Countries, experimental group children gained an average of 0.39 kg (95% C.I: 0.11 to 0.67) over an average of 19 months and 0.71 kg ( 95% C.I.: 0.48 to 0.95) over 11.3 months respectively. Results for weight were mixed in higher income countries. For height, results were mixed; height gain was greater for younger children. Attendance in lower income countries was higher in experimental groups than in controls; our results show an average increase of 4 to 6 days a year. Math gains were consistently higher for experimental groups in lower income countries; in CBAs, the Standardized Mean Difference was 0.66 (95% C.I. = 0.13 to 1.18). In short-term studies, small improvements in some cognitive tasks were found. 

**Authors&#039; conclusions **
School meals may have some small benefits for disadvantaged children. We recommend further well-designed studies on the effectiveness of school meals be undertaken, that results should be reported according to socio-economic status, and that researchers gather robust data on both processes and carefully chosen outcomes.
AD  - Univ Ottawa, Sch Psychol, Inst Populat Hlth, Ottawa, ON K1N 6N5, Canada. Univ Ottawa, Sch Psychol, Ctr Global Hlth, Ottawa, ON K1N 6N5, Canada. Kristjansson, EA (reprint author), Univ Ottawa, Sch Psychol, Inst Populat Hlth, 1 Stewart St, Ottawa, ON K1N 6N5, Canada.
AN  - WOS:000243747900041
AU  - Kristjansson,
AU  - E.
AU  - A.
AU  - Robinson,
AU  - V.
AU  - Petticrew,
AU  - M.
AU  - MacDonald,
AU  - B.
AU  - Krasevec,
AU  - J.
AU  - Janzen,
AU  - L.
AU  - Greenhalgh,
AU  - T.
AU  - Wells,
AU  - G.
AU  - MacGowna,
AU  - J.
AU  - Farmer,
AU  - A.
AU  - Shea,
AU  - B.
AU  - J.
AU  - Mayhew,
AU  - A.
AU  - Tugwell,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD004676.pub2
J2  - Cochrane Database Syst Rev.
KW  - RANDOMIZED CONTROLLED-TRIAL BONE-MINERAL ACCRETION AGED 10-12 YEARS BREAKFAST PROGRAM MILK INTERVENTION COGNITIVE PERFORMANCE NUTRITION-PROGRAMS ADOLESCENT GIRLS DIETARY QUALITY GROWTH Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 129RS Times Cited: 22 Cited Reference Count: 106 Kristjansson, E. A. Robinson, V Petticrew, M. MacDonald, B. Krasevec, J. Janzen, L. Greenhalgh, T. Wells, G. MacGowna, J. Farmer, A. Shea, B. J. Mayhew, A. Tugwell, P. 22 JOHN WILEY &amp; SONS LTD CHICHESTER COCHRANE DB SYST REV
PY  - 2007
SP  - 108
T2  - Cochrane Database of Systematic Reviews
TI  - School feeding for improving the physical and psychosocial health of disadvantaged elementary school children
UR  - &lt;Go to ISI&gt;://WOS:000243747900041http://onlinelibrary.wiley.com/store/10.1002/14651858.CD004676.pub2/asset/CD004676.pdf?v=1&amp;t=ib7tuxxu&amp;s=4a1962cd260cf92b4b4e32e185448aaf87263c17
ER  -
TY  - JOUR
AB  - Treatment reduces recidivism: The conclusion of the systematic review is that, overall, the programs studied work with regard to limiting relapses into crime. Looking at the effect of programs on all types of crime, there is a 6 per cent lower probability that juveniles who have taken part in a program relapse into crime, compared with those who have not taken part in the relevant treatment program. As an illustration, if 60 out of 100 of these juveniles would ordinarily relapse into crime after release from correction, treatment will reduce this to 56 out of 100. Looking exclusively at serious offenses, for example violence or other serious crime, which results in the offenders ending behind bars again, juveniles who have received treatment have a 9 per cent lower probability of recidivism. For example, if 40 out of 100 of these juveniles would ordinarily relapse into serious crime, treatment means that only 36 out of 100 will relapse. Although this is only a small effect, it can be very significant as serious crime involves considerable human and societal costs. 

Cognitive therapy works best:The positive effects are most apparent for cognitive or cognitive-behavioral programs. In cognitive treatments, participants must learn to recognize, control and &rdquo;reframe&rdquo; automatic and distorted thought patterns. Similarly cognitive-behavioral programs involve training in, for example, social skills, anger control, critical reasoning and creative thinking. In contrast, the effect of programs which focus exclusively on education and academic skills is more doubtful. The same applies for behavioral programs in which delinquent behavior is perceived as learned behavior which can be &rdquo;reversed&rdquo; using learning mechanisms and replaced with socially acceptable behavior. Programs focusing solely on group therapy or individual therapy, or those which only involve developing positive role models based on contemporaries seem to be less effective than programs with varied focus. 30 studies with more than 6,600 serious juvenile offenders: The systematic review includes a total of 30 studies with 6,658 juvenile offenders. 22 studies are from the US, four are from the UK and four more are from Canada. The studies were carried out from 1970 to 2003. Common for all of the studies is that at least half of the juvenile offenders are characterized as serious offenders, as they have committed offenses of a particularly violent nature, and/or they have three or more convictions. Participants were between 12 and 21, with an average age of 16. The treatment programs studied include psychological approaches, social and educational methods and environmental conditions all aimed at supporting prosocial behaviors. They all took place while the participants were incarcerated in different types of secure correction. Common for all the correctional facilities was that they held the juveniles accountable for their delinquent acts. Moreover they were characterized by physical restraint measures such as locked doors, fences and similar. Community programs, where offenders were in daily contact with the surrounding community, such as group homes, foster care or periodical detention were not included. Programs with several phases in which part of the treatment took place outside the institution were only included if more than half of the treatment took place in the institution. As there are only few studies with female participants, the results of the systematic review primarily apply for young men. Recidivism to delinquency was calculated using reports from the police and probation services. Follow-up periods varied from 6 months to 10 years with an average of slightly more than 31 months. Studies focusing on minor offenses such as shoplifting, traffic offenses and first-time offenses were excluded. Studies focusing primarily on sexual offenders were also excluded from the systematic review.
AU  - Garrido,
AU  - V.
AU  - Quintro,
AU  - L.
AU  - A.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2007.7
KW  - Adolescents
KW  - Violence
KW  - Correctional facilities
KW  - Juvenile delinquency
KW  - Crime
PY  - 2007
T2  - Campbell Systematic Reviews
TI  - Serious (Violent and Chronic) Juvenile Offenders: A Systematic Review of Treatment Effectiveness in Secure Corrections
ER  -
TY  - JOUR
AB  - **Objective:** 
To examine the clinical benefit, the harm and the cost-effectiveness of psychotherapies in comparison with no treatment, waiting-list controls, attention-placebos, and treatment as usual in depressed youths. 

**Method:** 
Meta-analyses were undertaken by using data from all relevant randomized-controlled trials identified by a comprehensive literature search. The primary outcome was relative risk (RR) of response. 

**Results:** 
We identified 27 studies containing 35 comparisons and 1744 participants. At post-treatment, psychotherapy was significantly superior (RR = 1.39, 95% CI 1.18-1.65, P = 0.0001, number-needed to treat 4.3). There was an evidence of the existence of small study effects, including a publication bias (P &lt; 0.001). The superiority of psychotherapy was no longer statistically significant (1.18 [0.94-1.47], P = 0.15) at 6-month follow-up. None of the studies reported adverse effects or cost-effectiveness outcomes. 

**Conclusion: **
Although the findings were biased by some small positive trials, psychotherapies appear to help depressed youths for the short term, but are no longer significantly favourable at 6-month follow-up.
AD  - Nagoya City Univ, Dept Psychiat &amp; Cognit Behav Med, Grad Sch Med Sci, Mizuho Ku, Nagoya, Aichi 4678601, Japan. Inst Psychiat, Sect Evidence Based Mental Hlth Hlth Serv, London, England. Inst Psychiat, Populat Res Dept, London, England. Watanabe, N (reprint author), Nagoya City Univ, Dept Psychiat &amp; Cognit Behav Med, Grad Sch Med Sci, Mizuho Ku, Mizuho Cho, Nagoya, Aichi 4678601, Japan. noriow@med.nagoya-cu.ac.jp
AN  - WOS:000248087900002
AU  - Watanabe,
AU  - N.
AU  - Hunot,
AU  - V.
AU  - Omori,
AU  - I.
AU  - M.
AU  - Churchill,
AU  - R.
AU  - Furukawa,
AU  - T.
AU  - A.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1600-0447.2007.01018.x
J2  - Acta Psychiatr. Scand.
KW  - adolescent child depressive disorder meta-analysis psychotherapy review COGNITIVE-BEHAVIORAL TREATMENT RANDOMIZED CONTROLLED-TRIAL INTERPERSONAL PSYCHOTHERAPY SCHOOL-CHILDREN PRIMARY-CARE FOLLOW-UP INTERVENTION EFFICACY THERAPY DISORDER Psychiatry
L1  - internal-pdf://1649307612/Watanabe-2007-Psychotherapy for depression amo.pdf
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 190VE Times Cited: 49 Cited Reference Count: 54 Watanabe, N. Hunot, V. Omori, I. M. Churchill, R. Furukawa, T. A. Furukawa, Toshi/B-9259-2011 51 BLACKWELL PUBLISHING OXFORD ACTA PSYCHIAT SCAND
PY  - 2007
SP  - 84-95
T2  - Acta Psychiatrica Scandinavica
TI  - Psychotherapy for depression among children and adolescents: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000248087900002http://onlinelibrary.wiley.com/store/10.1111/j.1600-0447.2007.01018.x/asset/j.1600-0447.2007.01018.x.pdf?v=1&amp;t=ib3ky5c5&amp;s=5cae46195bb085612b2ec3afba160ce0e971f51a
UR  - http://onlinelibrary.wiley.com/store/10.1111/j.1600-0447.2007.01018.x/asset/j.1600-0447.2007.01018.x.pdf?v=1&amp;t=j8yexj1z&amp;s=e23dc27a8349abdfe1b7343ad2e1ca0983b2be19
VL  - 116
ER  -
TY  - JOUR
AB  - **Background:** 
The provision of training for foster carers is now seen as an important factor contributing to the successful outcome of foster care placements. Since the late 1960s, foster carer training programs have proliferated, and few of the many published and unpublished training curricula have been systematically evaluated. The advent of cognitive-behavioural therapy (CBT) and the research evidence demonstrating its effectiveness as a psychotherapeutic treatment of choice for a range of emotional and behavioural problems, has prompted the development of CBT-based training programmes. CBT approaches to foster care training derive from a &#039;skill-based&#039; training format that also seeks to identify and correct problematic thinking patterns that are associated with dysfunctional behaviour by changing and/or challenging maladaptive thoughts and beliefs.

**Objectives:** 
To assess the effectiveness of cognitive-behavioural training interventions in improving a) looked-after children&#039;s behavioural/relationship problems, b) foster carers&#039; psychological well-being and functioning, c) foster family functioning, d) foster agency outcomes.

**Search methods:**
We searched databases including: CENTRAL (Cochrane Library Issue 3, 2006), MEDLINE (January 1966 to September 2006), EMBASE (January 1980 to September 2006), CINAHL (January 1982 to September 2006), PsycINFO (January 1872 to September 2006), ASSIA (January 1987 to September 2006), LILACS (up to September 2006), ERIC (January 1965 to September 2006), Sociological Abstracts (January 1963 to September 2006), and the National Research Register 2006 (Issue 3). We contacted experts in the field concerning current research.

**Selection criteria:** 
Random or quasi randomised studies comparing behavioural or cognitive-behavioural-based training intervention (in a group or one-to-one settings or both) versus a no-treatment or wait-list control, for foster parents/carers.

**Data collection and analysis:** 
Two authors independently assessed trial quality and extracted data. We contacted study authors for additional information.

**Main results:** 
Six trials involving 463 foster carers were included. Behavioural and cognitive-behavioural training interventions evaluated to date appear to have very little effect on outcomes relating to looked-after children, assessed in relation to psychological functioning, extent of behavioural problems and interpersonal functioning. Results relating to foster carer(s) outcomes also show no evidence of effectiveness in measures of behavioural management skills, attitudes and psychological functioning. Analysis pertaining to fostering agency outcomes did not show any significant results. However, caution is needed in interpreting these findings as their confidence intervals are wide.

**Authors&#039; conclusions:** 
There is currently little evidence about the efficacy of behavioural or cognitive-behavioural training intervention for foster carers. The need for further research in this area is highlighted.
AN  - CD003760
AU  - Turner,
AU  - W.
AU  - Macdonald,
AU  - G.
AU  - Dennis,
AU  - J.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003760.pub3
KW  - Aggression
KW  - Behavior Therapy [education] [methods]
KW  - Child Development
KW  - Cognitive Therapy [education] [methods]
KW  - Foster Home Care [methods] [psychology]
KW  - Randomized Controlled Trials as Topic
KW  - Social Behavior Disorders [therapy]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2007
T2  - Cochrane Database of Systematic Reviews
TI  - Behavioural and cognitive behavioural training interventions for assisting foster carers in the management of difficult behaviour
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003760.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003760.pub3/asset/CD003760.pdf?v=1&amp;t=iw7iwqfz&amp;s=7165b86d19a10b33b2d5bbbfb12fefefb3378c77
ER  -
TY  - JOUR
AB  - **Background:** 
Childhood-onset schizophrenia is schizophrenia with onset prior to the age of 13 years. Although it is rare, people who suffer from schizophrenia at an early age appear to have a clinically severe form of the illness with poor long-term prognosis. Antipsychotic medication is one way of managing this rare but serious mental illness.

**Objectives:** 
To examine the effects of antipsychotic medication for childhood-onset schizophrenia.

**Search methods:** 
We searched the Cochrane Schizophrenia Group Trials Register (November 2006 and February 2007), inspected references of all identified studies for further trials and contacted relevant pharmaceutical companies and authors of trials for additional information.

**Selection criteria:** 
We included all randomised clinical trials involving children and young people with a diagnosis of childhood onset schizophrenia (i.e. with a diagnosis of schizophrenia before the age of 13) comparing any antipsychotic drug with another antipsychotic or placebo.

**Data collection and analysis:** 
We reliably selected, quality assessed and extracted data from trials. We excluded data where more than 50% of participants in any group were lost to follow up. For homogenous dichotomous data we calculated random effects, relative risk (RR) and its 95% confidence interval (CI) and, where appropriate, number needed to treat (NNT) on an intention-to-treat basis. For normal continuous data we calculated the weighted mean difference (WMD).

**Main results:** 
From a total of 2062 citations, we identified six relevant trials. We categorised trials into three comparisons: atypical versus typical, atypical versus atypical and typical versus typical antipsychotic drugs. The only comparison to find any differences between treatment groups was atypical versus typical antipsychotic drugs. A few results from one study favoured the atypical antipsychotic clozapine over haloperidol in treating treatment resistant childhood-onset schizophrenia (n=21, WMD CGAS 17.00 CI 7.74 to 26.26; n=21, WMD Bunney-Hamburg Psychosis Rating Scale -3.60 CI -6.64 to -0.56). Participants on clozapine, however, were three times more likely to have drowsiness (1 RCT, n=21, RR 3.30 CI 1.23 to 8.85, NNH 2 CI 2 to 17) and half of the children receiving clozapine had neutropenia (1 RCT, n=21, RR 12, CI 0.75 to192.86).

**Authors&#039; conclusions:** 
There are few relevant trials and, presently, there is little conclusive evidence regarding the effects of antipsychotic medication for those with early onset schizophrenia. Some benefits were identified in using the atypical antipsychotic clozapine compared with haloperidol but the benefits were offset by an increased risk of serious adverse effects. Larger, more robust, trials are required.
AN  - CD004027
AU  - Kennedy,
AU  - E.
AU  - Kumar,
AU  - A.
AU  - Datta,
AU  - S.
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004027
KW  - Age of Onset
KW  - Antipsychotic Agents [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Schizophrenia [drug therapy]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Schiz
PY  - 2007
T2  - Cochrane Database of Systematic Reviews
TI  - Antipsychotic medication for childhood-onset schizophrenia
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004027.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004027.pub2/asset/CD004027.pdf?v=1&amp;t=iw7iqyd9&amp;s=4a0fa21fa392e65d4a4be2fd12c474b1c1f5b585
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To explicate differences between early and recent meta-analytic estimates of the effects of cognitive-behavioral therapy (CBT) for adolescent depression. 

**METHOD: **
Meta-analytic procedures were used to investigate whether methodological characteristics moderated mean effect sizes among 11 randomized, controlled trials of CBT focusing on adolescents meeting diagnostic criteria for unipolar depression. 

**RESULTS: **
Cumulative meta-analyses indicated that effects of CBT have decreased from large effects in early trials, and confidence intervals have become narrower. Effect sizes were significantly smaller among studies that used intent-to-treat analytic strategies, compared CBT to active treatments, were conducted in clinical settings, and featured greater methodological rigor based on CONSORT (Consolidated Standards of Reporting Trials) criteria. The mean posttreatment effect size of 0.53 was statistically significant. 

**CONCLUSIONS: **
Differences in estimates of the efficacy of CBT for depressed adolescents may stem from methodological differences between early and more recent investigations. Overall, results support the effectiveness of CBT for the treatment of adolescent depression.
AD  - Klein,Jesse B. Department of Psychiatry, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. jesseklein@northwestern.edu
AN  - 18049290
AU  - Klein,
AU  - J.
AU  - B.
AU  - Jacobs,
AU  - R.
AU  - H.
AU  - Reinecke,
AU  - M.
AU  - A.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/chi.0b013e3180592aaa
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
KW  - Adolescent *Cognitive Therapy/mt [Methods] *Depressive Disorder, Major/th [Therapy] Humans Treatment Outcome
L1  - internal-pdf://2624346284/Klein-2007-Cognitive-behavioral therapy for ad.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural
N1  - Klein, Jesse B Jacobs, Rachel H Reinecke, Mark A Comment in: Evid Based Ment Health. 2008 Aug;11(3):76; PMID: 18669678 F31 MH075308 (United States NIMH NIH HHS) F31 MH075308-01A1 (United States NIMH NIH HHS) F31MH075308 (United States NIMH NIH HHS)
PY  - 2007
SP  - 1403-13
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Cognitive-behavioral therapy for adolescent depression: a meta-analytic investigation of changes in effect-size estimates
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=18049290 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:18049290&amp;id=doi:&amp;issn=0890-8567&amp;isbn=&amp;volume=46&amp;issue=11&amp;spage=1403&amp;pages=1403-13&amp;date=2007&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Cognitive-behavioral+therapy+for+adolescent+depression%3A+a+meta-analytic+investigation+of+changes+in+effect-size+estimates.&amp;aulast=Klein&amp;pid=%3Cauthor%3EKlein+JB%3C%2Fauthor%3E%3CAN%3E18049290%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0890856709620372/1-s2.0-S0890856709620372-main.pdf?_tid=1a13f44e-1999-11e5-a9d3-00000aacb361&amp;acdnat=1435058286_17bece79e7bda55bd09790779fc51ea6
UR  - http://ovidsp.tx.ovid.com/ovftpdfs/FPDDNCDCDBALNL00/fs046/ovft/live/gv023/00004583/00004583-200711000-00002.pdf
VL  - 46
ER  -
TY  - JOUR
AB  - Self-management for students with autism is important both as a management tool and as a means to enhance students&#039; quality of life by empowering them to control their own behavior. This article reports the results of an examination of the efficacy of self-management for increasing appropriate behavior of children and youth with autism. Single-subject research using self-management of students with autism as an intervention was synthesized and the impact was analyzed across intervention and participants&#039; characteristics using the percentage of non-overlapping data (PND) metric. Average PND values suggest that self-management interventions are an effective treatment for increasing the frequency of appropriate behavior of students with autism. Implications for further research extending the use and understanding of self-management procedures for students diagnosed with autism are discussed. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Lee, Suk-Hyang: sukhyang@ku.edu Lee, Suk-Hyang: Beach Center on Disability, University of Kansas, Room 3136 Haworth Hall, 1200 Sunnyside Ave, Lawrence, KS, US, 66045-7534, sukhyang@ku.edu Lee, Suk-Hyang: Beach Center on Disability, University of Kansas, Lawrence, KS, US Simpson, Richard L.: University of Kansas, Lawrence, KS, US Shogren, Karrie A.: University of Texas, Austin, TX, US
AN  - 2007-05371-001
AU  - Lee,
AU  - S.
AU  - H.
AU  - Simpson,
AU  - R.
AU  - L.
AU  - Shogren,
AU  - K.
AU  - A.
DA  - Spr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/10883576070220010101
DP  - Ovid Technologies
KW  - self-management, students, autism, efficacy *Autism *Self Management *Students Self Efficacy Developmental Disorders &amp; Autism [3250] Human Male Female Childhood (birth-12 yrs) Adolescence (13-17 yrs)
LA  - English
M3  - Meta Analysis
PY  - 2007
SP  - 2-13
T2  - Focus on Autism and Other Developmental Disabilities
TI  - Effects and implications of self-management for students with autism: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc5&amp;AN=2007-05371-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F10883576070220010101&amp;issn=1088-3576&amp;isbn=&amp;volume=22&amp;issue=1&amp;spage=2&amp;pages=2-13&amp;date=2007&amp;title=Focus+on+Autism+and+Other+Developmental+Disabilities&amp;atitle=Effects+and+implications+of+self-management+for+students+with+autism%3A+A+meta-analysis.&amp;aulast=Lee&amp;pid=%3Cauthor%3ELee%2C+Suk-Hyang%3C%2Fauthor%3E%3CAN%3E2007-05371-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://foa.sagepub.com/content/22/1/2http://foa.sagepub.com/content/22/1/2.full.pdf
VL  - 22
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The present study compared the efficacy of psychotherapy for childhood anxiety disorders (excluding trials solely treating post-traumatic stress disorder or obsessive-compulsive disorder). 

**METHODS: **
The meta-analysis included studies that met the basic CONSORT (consolidated standards of reporting trials) criteria. Several outcome variables (e.g. effect sizes, percentage of recovery) were analyzed using completer and intent-to-treat analyses during post-treatment and follow-up assessment. Twenty-four studies published by March 2005 were included in this meta-analysis. 

**RESULTS: **
In all the included studies, the active treatment condition was cognitive-behavioral. The overall mean effect of treatment was 0.86. No differences in outcome were found between individual and group treatments or child- and family-focused treatments. Follow-up data demonstrated that treatment gains were maintained up to several years after treatment. 

**CONCLUSIONS:**
These findings provide evidence that anxiety disorders in children can be treated efficaciously. The gathered data support the clinical utility of cognitive-behavioral therapy in this regard. Randomized controlled trial studies investigating treatments other than cognitive-behavioral therapy are missing.

Copyright 2007 S. Karger AG, Basel.
AD  - In-Albon,Tina. Department of Clinical Child and Adolescent Psychology, University of Basel, Basel, Switzerland.
AN  - 17170560
AU  - In-Albon,
AU  - T.
AU  - Schneider,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1159/000096361
DP  - Ovid Technologies
J2  - Psychother Psychosom
KW  - *Anxiety Disorders/th [Therapy] Child Humans *Psychotherapy/mt [Methods]
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - In-Albon, Tina Schneider, Silvia
PY  - 2007
SP  - 15-24
T2  - Psychotherapy and Psychosomatics
TI  - Psychotherapy of childhood anxiety disorders: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17170560 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17170560&amp;id=doi:&amp;issn=0033-3190&amp;isbn=&amp;volume=76&amp;issue=1&amp;spage=15&amp;pages=15-24&amp;date=2007&amp;title=Psychotherapy+%26+Psychosomatics&amp;atitle=Psychotherapy+of+childhood+anxiety+disorders%3A+A+meta-analysis.&amp;aulast=In-Albon&amp;pid=%3Cauthor%3EIn-Albon+T%3C%2Fauthor%3E%3CAN%3E17170560%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://media.proquest.com/media/pq/classic/doc/1193236351/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Tina+In-Albon%3BSchneider%2C+Silvia&amp;cit%3Atitle=Psychotherapy+of+Childhood+Anxiety+Disorders%3A+A+Meta-Analysis&amp;cit%3Apub=Psychotherapy+and+Psychosomatics&amp;cit%3Avol=76&amp;cit%3Aiss=1&amp;cit%3Apg=15&amp;cit%3Adate=Dec+2006&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMzA2MTA0NDcyNjo5ODMwMTcSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNDEyMTYyCTIzNTQ2ODE4MDoNRG9jdW1lbnRJbWFnZUIBMFIGT25saW5lWgJGVGIDUEZUagoyMDA2LzEyLzAxcgoyMDA2LzEyLzMxegCCASlQLTEwMDAyNzMtMzEwNzUtQ1VTVE9NRVItMTAwMDAxNTctMTExNTExMpIBBk9ubGluZcoBB0VuZE5vdGXSARJTY2hvbGFybHkgSm91cm5hbHOaAgdQcmVQYWlkqgIoT1M6RU1TLVBkZkRvY1ZpZXdCYXNlLWdldE1lZGlhVXJsRm9ySXRlbcoCD0ZlYXR1cmV8QXJ0aWNsZdICAVniAgFO8gIA&amp;_s=ILVFYUCPzaul95LQ1GQVXpt%2B%2FUA%3D
VL  - 76
ER  -
TY  - JOUR
AB  - We conducted a meta-analysis using 20 randomised controlled studies of cognitive behavioural therapy (CBT) for anxiety disorders in children and adolescents. 

The mean pre-post effect size was d = 0.94, which was maintained at follow-up. The mean effect size when comparing the CBT and control group was d = 0.61. Within the CBT group, the mean effect size of university clinics (d = 0.77) was larger than that of other clinics (d = 0.37). The difference in effect sizes was hardly noticeable when comparing CBT with family or parents and CBT with child only (d = 0.03). 

Further studies are required to examine the effectiveness of family CBT versus child CBT. 

&copy; 2007 Association for Child and Adolescent Mental Health.
AD  - (Ishikawa) Faculty of Education and Culture, University of Miyazaki, Miyazaki, Japan (Okajima, Matsuoka, Sakano) School of Psychological Science, Health Sciences University of Hokkaido, Hokkaido, Japan S.I. Ishikawa, Faculty of Education and Culture, University of Miyazaki, Miyazaki, Japan. E-mail: ishinn@cc.miyazaki-u.ac.jp
AN  - 2007514649
AU  - Ishikawa,
AU  - S.
AU  - I.
AU  - Okajima,
AU  - I.
AU  - Matsuoka,
AU  - H.
AU  - Sakano,
AU  - Y.
DA  - November
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1475-3588.2006.00433.x
DP  - Ovid Technologies
KW  - Adolescent Anxiety disorders Child Cognitive behavioural therapy Meta-analysis anxiety disorder/th [Therapy] article child care child psychiatry clinical effectiveness clinical trial cognitive therapy controlled clinical trial effect size family attitud
LA  - English
PY  - 2007
SP  - 164-172
T2  - Child and Adolescent Mental Health
TI  - Cognitive behavioural therapy for anxiety disorders in children and adolescents: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed8&amp;AN=2007514649 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:10.1111%2Fj.1475-3588.2006.00433.x&amp;issn=1475-357X&amp;isbn=&amp;volume=12&amp;issue=4&amp;spage=164&amp;pages=164-172&amp;date=2007&amp;title=Child+and+Adolescent+Mental+Health&amp;atitle=Cognitive+behavioural+therapy+for+anxiety+disorders+in+children+and+adolescents%3A+A+meta-analysis&amp;aulast=Ishikawa&amp;pid=%3Cauthor%3EIshikawa+S.-I.%3C%2Fauthor%3E%3CAN%3E2007514649%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1475-3588.2006.00433.x/asset/j.1475-3588.2006.00433.x.pdf?v=1&amp;t=ib7ngrhx&amp;s=9c1b1108a62767ea62039b0a7e452fc6472b0f7d
VL  - 12
ER  -
TY  - JOUR
AB  - This review examines the evidence concerning the efficacy and effectiveness of universal, school-based interventions designed to prevent the development of depression in children and adolescents. It evaluates the outcomes of research in relation to standards of evidence specified by the Society for Prevention Research (Flay et al., 2005). 

The limited evidence available brings into doubt the efficacy and effectiveness of current universal, school-based approaches to the prevention of depression, suggesting that the widespread dissemination of such interventions would be premature. 

Relatively brief programs, that focus specifically on enhancing individual skills and characteristics of the individual in the absence of environmental change, may be insufficient to produce lasting effects in the prevention of depression among children and adolescents.
AD  - Spence,Susan H. Department of Psychology, Division of Linguistics and Psychology, Macquarie University, Australia. sue.spence@mq.edu.au
AN  - 17537069
AU  - Spence,
AU  - S.
AU  - H.
AU  - Shortt,
AU  - A.
AU  - L.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 0.1111/j.1469-7610.2007.01738.x
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
KW  - Adolescent Child Depressive Disorder/di [Diagnosis] *Depressive Disorder/pc [Prevention &amp; Control] *Diffusion of Innovation Health Education Humans *Mass Screening Risk Factors *School Health Services Social Environment Treatment Outcome United States
LA  - English
M3  - Review
N1  - Spence, Susan H Shortt, Alison L
PY  - 2007
SP  - 526-42
T2  - Journal of Child Psychology and Psychiatry and Allied Disciplines
TI  - Research Review: Can we justify the widespread dissemination of universal, school-based interventions for the prevention of depression among children and adolescents?
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17537069 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17537069&amp;id=doi:&amp;issn=0021-9630&amp;isbn=&amp;volume=48&amp;issue=6&amp;spage=526&amp;pages=526-42&amp;date=2007&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Research+Review%3A+Can+we+justify+the+widespread+dissemination+of+universal%2C+school-based+interventions+for+the+prevention+of+depression+among+children+and+adolescents%3F.&amp;aulast=Spence&amp;pid=%3Cauthor%3ESpence+SH%3C%2Fauthor%3E%3CAN%3E17537069%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1469-7610.2007.01738.x/asset/j.1469-7610.2007.01738.x.pdf?v=1&amp;t=ib8zygx9&amp;s=8019e94cc6addc6a3f54488c5c6b5f5b116c350d
VL  - 48
ER  -
TY  - JOUR
AB  - **Background:** 
Homeopathy is one form of complementary/alternative medicine which is promoted as being a safe and effective form of treatment for children and adults. Within the UK homeopathy use is estimated at 1.9% of the adult population (Thomas 2004), and around 11% for children under 16 years (Simpson 2001). There has been increased interest in homeopathy&#039;s potential as a non-pharmacological intervention for attention deficit/hyperactivity disorder as an alternative to the use of stimulant medications such as Ritalin. Homeopathy is a system of medicine based on the principle of treating &quot;like with like&quot; using various dilutions of natural or man-made substances. Homeopathy focuses on the unique characteristics of each patient&#039;s experience and symptomatology and uses this information to determine the appropriate prescription for each patient.

**Objectives:** 
To assess the safety and effectiveness of homeopathy as a treatment for attention deficit/hyperactivity disorder.

**Search methods:** 
We searched a wide set of databases from their inception to March 2006 including: CENTRAL, MEDLINE, AMED, BIOSIS, CISCOM, CINAHL, Dissertation Abstracts, ECH (European Committee for Homeopathy thesis database), EMBASE, ERIC, HomInform (Glasgow Homeopathic Hospital Library), LILACS, PsycINFO, Science Citation Index, SIGLE, GIRI - International congress on ultra-low doses, Liga Medicorum Homeopathica Internationalis. We contacted experts in the field about ongoing or current research.

**Selection criteria:** 
All studies where individualised, clinical or formula homeopathy had been used to treat participants with ADHD or HKD who were randomly or quasi-randomly allocated to either true treatment or a control were selected. Control groups could include wait-list, no treatment, medication, placebo homeopathy, educational or behavioural interventions.

**Data collection and analysis:** 
Data from four eligible studies (total n = 168) were extracted and entered into RevMan. Results were synthesised and estimates of the effect sizes were calculated and presented as appropriate (using standardised mean differences) in both graphical and narrative form (narrative only was used where no effect size calculation was possible).

**Main results:** 
The forms of homeopathy evaluated to date do not suggest significant treatment effects for the global symptoms, core symptoms of inattention, hyperactivity or impulsivity, or related outcomes such as anxiety in Attention Deficit/Hyperactivity Disorder.

**Authors&#039; conclusions:** 
There is currently little evidence for the efficacy of homeopathy for the treatment of ADHD. Development of optimal treatment protocols is recommended prior to further randomised controlled trials being undertaken.
AN  - CD005648
AU  - Heirs,
AU  - M.
AU  - Dean,
AU  - M.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd005648.pub2
KW  - Attention Deficit Disorder with Hyperactivity [drug therapy]
KW  - Homeopathy [methods]
KW  - Hyperkinesis [drug therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2007
T2  - Cochrane Database of Systematic Reviews
TI  - Homeopathy for attention deficit/hyperactivity disorder or hyperkinetic disorder
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005648.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005648.pub2/asset/CD005648.pdf?v=1&amp;t=iw7jo4eo&amp;s=4421cb70ec44bf05beafc8a1adea9cb0a636c78a
ER  -
TY  - JOUR
AB  - Universal, school-based programs, intended to prevent violent behavior, have been used at all grade levels from pre-kindergarten through high school. 

These programs may be targeted to schools in a high-risk area-defined by low socioeconomic status or high crime rate-and to selected grades as well. 

All children in those grades receive the programs in their own classrooms, not in special pull-out sessions. According to the criteria of the systematic review methods developed for the Guide to Community Preventive Services (Community Guide), there is strong evidence that universal, school-based programs decrease rates of violence among school-aged children and youth. 

Program effects were consistent at all grade levels. An independent, recently updated meta-analysis of school-based programs confirms and supplements the Community Guide findings.
AD  - Hahn,Robert. National Center for Health Marketing, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA. Rhahn@cdc.gov
AN  - 17675013
AU  - Hahn,
AU  - R.
AU  - Fuqua-Whitley,
AU  - D.
AU  - Wethington,
AU  - H.
AU  - Lowy,
AU  - J.
AU  - Crosby,
AU  - A.
AU  - Fullilove,
AU  - M.
AU  - Johnson,
AU  - R.
AU  - Liberman,
AU  - A.
AU  - Moscicki,
AU  - E.
AU  - Price,
AU  - L.
AU  - Snyder,
AU  - S.
AU  - Tuma,
AU  - F.
AU  - Cory,
AU  - S.
AU  - Stone,
AU  - G.
AU  - Mukhopadhaya,
AU  - K.
AU  - Chattopadhyay,
AU  - S.
AU  - Dahlberg,
AU  - L.
AU  - Task
AU  - Force
AU  - on
AU  - Community
AU  - Preventive
AU  - Services
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.amepre.2007.04.012
DP  - Ovid Technologies
J2  - Am J Prev Med
KW  - *Aggression Humans Outcome Assessment (Health Care) *Preventive Health Services Preventive Medicine *Program Evaluation *School Health Services Schools Social Class Students United States *Violence/pc [Prevention &amp; Control]
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
N1  - Hahn, Robert Fuqua-Whitley, Dawna Wethington, Holly Lowy, Jessica Crosby, Alex Fullilove, Mindy Johnson, Robert Liberman, Akiva Moscicki, Eve Price, LeShawndra Snyder, Susan Tuma, Farris Cory, Stella Stone, Glenda Mukhopadhaya, Kaushik Chattopadhyay, Sajal Dahlberg, Linda Task Force on Community Preventive Services Comment in: Am J Prev Med. 2007 Aug;33(2 Suppl):S101-3; PMID: 17675008 Comment in: Am J Prev Med. 2007 Aug;33(2 Suppl):S109-11; PMID: 17675011 Comment in: Am J Prev Med. 2007 Aug;33(2 Suppl):S107-8; PMID: 17675010 Comment in: Am J Prev Med. 2007 Aug;33(2 Suppl):S104-6; PMID: 17675009
PY  - 2007
SP  - S114-29
T2  - American Journal of Preventive Medicine
TI  - Effectiveness of universal school-based programs to prevent violent and aggressive behavior: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17675013
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17675013&amp;id=doi:&amp;issn=0749-3797&amp;isbn=&amp;volume=33&amp;issue=2&amp;spage=S114&amp;pages=S114-29&amp;date=2007&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=Effectiveness+of+universal+school-based+programs+to+prevent+violent+and+aggressive+behavior%3A+a+systematic+review.&amp;aulast=Hahn&amp;pid=%3Cauthor%3EHahn+R%3C%2Fauthor%3E%3CAN%3E17675013%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0749379707002371/1-s2.0-S0749379707002371-main.pdf?_tid=bf160892-167e-11e5-ab6e-00000aab0f6b&amp;acdnat=1434717113_c2ea4b586923ec9fbb63dff836ebdcf7
VL  - 33
ER  -
TY  - JOUR
AB  - **Rationale **
Pediatric anxiety is a prevalent psychiatric disorder that may have important implications for school, social, and academic function. Psychopharmacological approaches to the treatment of pediatric anxiety have expanded over the past 20 years and increasing empirical evidence helps guide current clinical practice. 

**Objective **
To review studies which examine the pharmacological treatment of pediatric anxiety disorders, including obsessive-compulsive disorder and to summarize treatment implications. 

**Methods **
All relevant studies were searched using MEDLINE and PsycINFO search engines, supplemented by a manual bibliographical search; studies published between 1985 and 2006 that met inclusion criteria were examined. 

**Results** 
This article provides a systematic review of the psychopharmacological treatment of pediatric anxiety disorders based on available empirical evidence, with a focus on randomized controlled trials. General treatment principles and pharmacological management of specific pediatric anxiety disorders are also reviewed. 

**Conclusion** 
There is good evidence to support the efficacy of several pharmacological agents including the selective serotonin reuptake inhibitors to treat pediatric anxiety and obsessive-compulsive disorder, although there are still many unanswered questions.
AD  - Johns Hopkins Univ, Sch Med, Div Child &amp; Adolescent Psychiat, Dept Psychiat &amp; Behav Sci, Baltimore, MD USA. Reinblatt, SP (reprint author), Johns Hopkins Univ, Sch Med, Div Child &amp; Adolescent Psychiat, Dept Psychiat &amp; Behav Sci, 600 N Wolfe St,CMSC 312, Baltimore, MD USA. sreinbl1@jhmi.edu
AN  - WOS:000244304000007
AU  - Reinblatt,
AU  - S.
AU  - P.
AU  - Riddle,
AU  - M.
AU  - A.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://doi.org/10.1007/s00213-006-0644-4
J2  - Psychopharmacology
KW  - antidepressant psychopharmacology pediatric anxiety disorders anxiety disorders treatment child and adolescent SSRI generalized anxiety disorder social anxiety disorder obsessive compulsive disorder OBSESSIVE-COMPULSIVE DISORDER SEROTONIN REUPTAKE INHIB
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 137PH Times Cited: 28 Cited Reference Count: 135 Reinblatt, Shauna P. Riddle, Mark A. 28 SPRINGER NEW YORK PSYCHOPHARMACOLOGY
PY  - 2007
SP  - 67-86
T2  - Psychopharmacology
TI  - The pharmacological management of childhood anxiety disorders: a review
UR  - &lt;Go to ISI&gt;://WOS:000244304000007
UR  - https://link.springer.com/article/10.1007%2Fs00213-006-0644-4
VL  - 191
ER  -
TY  - JOUR
AB  - This meta-analysis examines more than twenty-five years of evidence to determine whether participation in school-based conflict resolution education (CRE) contributes to reduced antisocial behaviors among youth in kindergarten through twelfth grade in U.S. schools. Evidence from thirty-six studies, representing 4,971 students, shows improvements in antisocial behaviors in CRE participants compared to control groups (Effect Size = .26), with larger effects observed during mid-adolescence (ES = .53) and early adolescence (ES = .22) compared to middle childhood (ES = .06). Improvements in antisocial behavior outcomes attributable to CRE are significant in both practical and statistical terms and are similar for different CRE program approaches. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Garrard, Wendy M.: Center for Evaluation Research and Methodology, Vanderbilt Institute for Public Policy Studies, TN, US Lipsey, Mark W.: Center for Evaluation Research and Methodology, Vanderbilt Institute for Public Policy Studies, TN, US
AN  - 2007-17681-002
AU  - Garrard,
AU  - W.
AU  - M.
AU  - Lipsey,
AU  - M.
AU  - W.
DA  - Fal
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/crq.188
DP  - Ovid Technologies
KW  - conflict resolution education, antisocial behavior, kindergartens *Antisocial Behavior *Conflict Resolution *Education *Kindergartens Educational Psychology [3500] Human us
LA  - English
M3  - Meta Analysis
N1  - Special Issue: A world of possibilities: Conflict resolution education and peace education around the globe
PY  - 2007
SP  - 9-38
T2  - Conflict Resolution Quarterly
TI  - Conflict resolution education and antisocial behavior in U.S. schools: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc5&amp;AN=2007-17681-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1002%2Fcrq.188&amp;issn=1536-5581&amp;isbn=&amp;volume=25&amp;issue=1&amp;spage=9&amp;pages=9-38&amp;date=2007&amp;title=Conflict+Resolution+Quarterly&amp;atitle=Conflict+resolution+education+and+antisocial+behavior+in+U.S.+schools%3A+A+meta-analysis.&amp;aulast=Garrard&amp;pid=%3Cauthor%3EGarrard%2C+Wendy+M%3C%2Fauthor%3E%3CAN%3E2007-17681-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1002/crq.188/asset/188_ftp.pdf?v=1&amp;t=ib92hr2h&amp;s=27a324c91977f9384b58f380e8ccedb762841396
VL  - 25
ER  -
TY  - JOUR
AB  - This meta-analysis examined the effectiveness of video modeling and video self-modeling (VSM) interventions for children and adolescents with autism spectrum disorders (ASD). 

Twenty-three single-subject design studies were included in the meta-analysis. Intervention, maintenance, and generalization effects were measured by computing the percentage of nonoverlapping data points (PND). 

Results suggest that video modeling and VSM are effective intervention strategies for addressing social-communication skills, functional skills, and behavioral functioning in children and adolescents with ASD. Results also indicate that these procedures promote skill acquisition and that skills acquired via video modeling and VSM are maintained over time and transferred across persons and settings. The results suggest that video modeling and VSM intervention strategies meet criteria for designation as an evidence-based practice. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Bellini, Scott: sbellini@indiana.edu Bellini, Scott: Indiana Resource Center for Autism, Indiana Institute on Disability and Community, Indiana University-Bloomington, 2853 E. 10th St., Bloomington, IN, US, 47408-2696, sbellini@indiana.edu Bellini, Scott: Indiana Resource Center for Autism, Indiana Institute on Disability and Community, Indiana University-Bloomington, Bloomington, IN, US Akullian, Jennifer: Indiana Resource Center for Autism, Indiana Institute on Disability and Community, Indiana University-Bloomington, Bloomington, IN, US
AN  - 2007-03233-002
AU  - Bellini,
AU  - S.
AU  - Akullian,
AU  - J.
DA  - Spr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/001440290707300301
DP  - Ovid Technologies
KW  - video modeling, video self modeling interventions, autism spectrum disorders, social communication skills, intervention strategies, evidence based practice *Evidence Based Practice *Intervention *Pervasive Developmental Disorders *Videotapes Communicati
LA  - English
M3  - Meta Analysis
PY  - 2007
SP  - 264-287
T2  - Exceptional Children
TI  - A Meta-Analysis of Video Modeling and Video Self-Modeling Interventions for Children and Adolescents With Autism Spectrum Disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc5&amp;AN=2007-03233-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:&amp;issn=0014-4029&amp;isbn=&amp;volume=73&amp;issue=3&amp;spage=264&amp;pages=264-287&amp;date=2007&amp;title=Exceptional+Children&amp;atitle=A+Meta-Analysis+of+Video+Modeling+and+Video+Self-Modeling+Interventions+for+Children+and+Adolescents+With+Autism+Spectrum+Disorders.&amp;aulast=Bellini&amp;pid=%3Cauthor%3EBellini%2C+Scott%3C%2Fauthor%3E%3CAN%3E2007-03233-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 73
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
The objective of this study was to evaluate the efficacy and safety of atomoxetine in children and adolescents.

**MATERIALS AND METHODS: **
We searched for studies published between 1985 and 2006 through Medline, PubMed, PsychInfo and Cochrane Central Register of Controlled Trials (CENTRAL 2006 Issue 3) using keywords related to atomoxetine and attention-deficit/hyperactivity disorder (ADHD) and scanned though reference lists. We included nine randomized placebo-controlled trials (atomoxetine:placebo = 1,150:678). 

**RESULTS: **
Atomoxetine was superior (p &lt; 0.01) to placebo in reducing ADHD symptoms across different scales (Attention-Deficit/Hyperactivity Disorder Rating Scale-IV, Conners&#039; Parent and Teacher Rating Scales-Revised:Short Form, Clinical Global Impression-Severity) rated by different raters (parent, teacher, clinician). The number-needed-to-treat (NNTs) for treatment response and relapse prevention were 3.43 (95% CI, 2.79-4.45) and 10.30 (95% CI, 5.89-40.62), respectively. 

High baseline ADHD symptoms (p = 0.02) was associated with greater reduction in ADHD symptoms, whereas male gender (p = 0.02), comorbid oppositional defiant disorder (ODD) status (p = 0.01) and ADHD hyperactive/impulsive subtype (p = 0.01) were associated with smaller reductions. 

The commonest adverse events were gastrointestinal [appetite decrease, number-needed-to-harm (NNH) = 8.81; abdominal pain, NNH = 22.48; vomiting, NNH = 29.96; dyspepsia, NNH = 49.38] and sleep related (somnolence, NNH = 19.41). Young age (p = 0.03) and high baseline hyperactive/impulsive symptoms (p &lt; 0.01) were associated with more adverse events, whereas ADHD inattentive subtype (p = 0.04) was associated with less adverse events. 

Quality of life using Child Health Questionnaire (CHQ) improved (p &lt; 0.01) with atomoxetine treatment. Both ADHD and ODD symptoms (p &lt; 0.01) were reduced in comorbid ADHD+ODD, and ODD status was not associated with more adverse events. Efficacy and side effects were not altered by comorbid general anxiety disorder or major depression. 

**CONCLUSIONS: **
Atomoxetine is efficacious in reducing ADHD symptoms. It may have a role in treating comorbid ODD or depression, and probably in comorbid anxiety.
AD  - Cheng,Jackie Y W. Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Hong Kong, Hong Kong. jackieyg@hku.hk
AN  - 17572882
AU  - Cheng,
AU  - J.
AU  - Y.
AU  - Chen,
AU  - R.
AU  - Y.
AU  - Ko,
AU  - J.
AU  - S.
AU  - Ng,
AU  - E.
AU  - M.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s00213-007-0840-x
DP  - Ovid Technologies
J2  - Psychopharmacology (Berl)
KW  - Adolescent Adrenergic Uptake Inhibitors/ae [Adverse Effects] Adrenergic Uptake Inhibitors/tu [Therapeutic Use] *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] Child Female Humans Male Propylamines/ae [Adverse Effects] *Propylamines/tu [
LA  - English
M3  - Meta-Analysis
N1  - Cheng, Jackie Y W Chen, Ronald Y L Ko, John S N Ng, Emil M L
PY  - 2007
SP  - 197-209
T2  - Psychopharmacology
TI  - Efficacy and safety of atomoxetine for attention-deficit/hyperactivity disorder in children and adolescents-meta-analysis and meta-regression analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=17572882
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17572882&amp;id=doi:&amp;issn=0033-3158&amp;isbn=&amp;volume=194&amp;issue=2&amp;spage=197&amp;pages=197-209&amp;date=2007&amp;title=Psychopharmacology&amp;atitle=Efficacy+and+safety+of+atomoxetine+for+attention-deficit%2Fhyperactivity+disorder+in+children+and+adolescents-meta-analysis+and+meta-regression+analysis.&amp;aulast=Cheng&amp;pid=%3Cauthor%3ECheng+JY%3C%2Fauthor%3E%3CAN%3E17572882%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs00213-007-0840-x
VL  - 194
ER  -
TY  - JOUR
AB  - **Objective: **
To establish the nature and efficacy of Australian school-based prevention and early intervention programs for anxiety and depression. Data sources: Cochrane, Psychlnfo and PubMed databases, and the Primary Mental Health Care Australian Resource Centre database, were searched in June 2006. Additional materials were obtained from program websites, reference lists and authors. 

**Study selection:**
Programs that were developed in Australia or trialled in Australia and addressed anxiety, depression, or resilience were included. 

**Data synthesis: **
24 efficacy or effectiveness trials of 9 intervention programs were identified. Most were based on cognitive behaviour therapy, interpersonal therapy or psychoeducation. Six were universal interventions, two were indicated programs and one was a treatment program. Most were associated with short-term improvements or symptom reduction at follow-up. 

**Conclusions: **
A number of schools programs produce positive outcomes. However, even well established programs require further, evaluation to establish readiness for broad dissemination as outlined. in the standards of the Society for Prevention Research.
AD  - Australian Natl Univ, Mental Hlth Res Ctr, Canberra, ACT, Australia. Neil, AL (reprint author), Australian Natl Univ, Mental Hlth Res Ctr, Canberra, ACT, Australia. alison.neil@anu.edu.au
AN  - WOS:000245998300009
AU  - Neil,
AU  - A.
AU  - L.
AU  - Christensen,
AU  - H.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /pubmed/17371212
J2  - Med. J. Aust.
KW  - LONG-TERM OUTCOMES ADOLESCENT DEPRESSION CONTROLLED-TRIAL FOLLOW-UP UNIVERSAL CHILDREN SYMPTOMS DISORDERS CHILDHOOD EFFICACY Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 161EW Times Cited: 36 Cited Reference Count: 43 Neil, Alison L. Christensen, Helen Calear, Alison/D-4191-2009; Christensen, Helen/F-5053-2012 Calear, Alison/0000-0002-7028-725X; 37 AUSTRALASIAN MED PUBL CO LTD PYRMONT MED J AUSTRALIA
PY  - 2007
SP  - 305-308
T2  - Medical Journal of Australia
TI  - Australian school-based prevention and early intervention programs for anxiety and depression: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000245998300009https://www.mja.com.au/system/files/issues/186_06_190307/nei10799_fm.pdf
VL  - 186
ER  -
TY  - JOUR
AB  - The relationship between cognitive-behavioral interventions and therapies on the one hand and school dropout outcomes and violent verbal or physical aggression on the other hand for secondary-age youth with disabilities was explored in a systematic review. 

A total of 16 studies intervening with 791 youth with behavioral disorders, attention-deficit/hyperactivity disorder, and learning disabilities were reviewed.

The findings of this review strongly support the efficacy of the use of cognitive-behavioral interventions across educational environments, disability types, age groups, and gender in the reduction of dropout and correlates of dropout. 

A series of more detailed implications for practice are suggested, as well as directions to the reader to locate more detailed descriptions of how these interventions might be implemented in their secondary education environments.
AD  - Colorado State Univ, Sch Educ, Ft Collins, CO 80523 USA. Colorado State Univ, Coll Appl Human Sci, Ft Collins, CO 80523 USA. Colorado State Univ, Occupat Therapy Dept, Ft Collins, CO 80523 USA. Appalachian State Univ, Dept Language Reading &amp; Except, Boone, NC 28608 USA. Cobb, B (reprint author), Colorado State Univ, Sch Educ, Ft Collins, CO 80523 USA.
AN  - WOS:000240760600002
AU  - Cobb,
AU  - B.
AU  - Sample,
AU  - P.
AU  - L.
AU  - Alwell,
AU  - M.
AU  - Johns,
AU  - N.
AU  - R.
DA  - Sep-Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/07419325060270050201
J2  - Remedial Spec. Educ.
KW  - SELF-MANAGEMENT DEVELOPMENTAL-DISABILITIES SCHOOL-STUDENTS PREVENTION PEOPLE ANGER METAANALYSIS ADOLESCENTS INSTRUCTION AGGRESSION Education, Special
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 087RT Times Cited: 5 Cited Reference Count: 55 Cobb, Brian Sample, Pat L. Alwell, Morgen Johns, Nikole R. 5 PRO-ED INC AUSTIN REM SPEC EDUC
PY  - 2006
SP  - 259-275
T2  - Remedial and Special Education
TI  - Cognitive-behavioral interventions, dropout, and youth with disabilities - A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000240760600002http://rse.sagepub.com/content/27/5/259http://rse.sagepub.com/content/27/5/259.full.pdf
VL  - 27
ER  -
TY  - JOUR
AB  - Given high rates of attention-deficit/hyperactivity disorder (ADHD) diagnosed in children, knowledge of effective treatment is crucial. To this end, a meta-analysis of parent-involved psychosocial treatment was undertaken to determine its effect on a number of outcomes salient to children with ADHD. Sixteen studies met the criteria for the meta-analysis. Findings indicated that the impact of treatment on ADHD was low compared to comparison and/or control conditions, whereas child-internalizing symptoms and academic problems were better affected by family involvement. Teachers reported the highest effect sizes followed by parents themselves. Although parent involvement might be important for affecting the internalizing symptoms and academic problems that plague children with ADHD, ADHD and externalizing symptoms might be better targeted by other interventions. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Corcoran, Jacqueline: jcorcora@mail1.vcu.edu Corcoran, Jacqueline: School of Social Work, Virginia Commonwealth University, 6295 Edsall Road, Suite 210, Alexandria, VA, US, 22312, jcorcora@mail1.vcu.edu Corcoran, Jacqueline: Virginia Commonwealth University, Alexandria, VA, US Dattalo, Patrick: Virginia Commonwealth University, Alexandria, VA, US
AN  - 2006-20200-001
AU  - Corcoran,
AU  - J.
AU  - Dattalo,
AU  - P.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1049731506289127
DP  - Ovid Technologies
KW  - parent involvement, attention deficit hyperactivity disorder, psychosocial treatment, childhood development *Attention Deficit Disorder with Hyperactivity *Childhood Development *Parental Involvement Psychosocial Factors Developmental Disorders &amp; Autism
LA  - English
M3  - Meta Analysis
PY  - 2006
SP  - 561-570
T2  - Research on Social Work Practice
TI  - Parent Involvement in Treatment for ADHD: A Meta-Analysis of the Published Studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc5&amp;AN=2006-20200-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F1049731506289127&amp;issn=1049-7315&amp;isbn=&amp;volume=16&amp;issue=6&amp;spage=561&amp;pages=561-570&amp;date=2006&amp;title=Research+on+Social+Work+Practice&amp;atitle=Parent+Involvement+in+Treatment+for+ADHD%3A+A+Meta-Analysis+of+the+Published+Studies.&amp;aulast=Corcoran&amp;pid=%3Cauthor%3ECorcoran%2C+Jacqueline%3C%2Fauthor%3E%3CAN%3E2006-20200-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rsw.sagepub.com/content/16/6/561http://rsw.sagepub.com/content/16/6/561.full.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - Depression in children and adolescents is considerably undertreated, and the school may be a good setting for identifying and treating depression. 

We conducted a meta-analysis of studies in which students were screened for depression, and those with depressive symptoms were treated with a psychological intervention. Only randomised controlled trials were included. Eight studies met the inclusion criteria. 

Five studies focused on younger children (7-14 years) and three studies were aimed at adolescents (12-19 years). In total 5803 students were screened, of whom 7.2% were included in the intervention studies (95% CI: 7.1-7.3). The &#039;numbers-needed-to-screen&#039; was 31 (95% CI: 27-32), which means that 31 students had to be screened in order to generate one successfully treated case of depression. 

The effects of the psychological treatments at post-test were compared to control conditions in the 8 studies comprising 12 contrast groups, with a total of 413 students. The mean effect size was 0.55 (95% CI: 0.35-0.76). There were not enough studies to examine whether specific psychotherapies were superior to other psychotherapies. 

Although the number of studies is small and their quality is limited, screening and early intervention at schools may be an effective strategy to reduce the burden of disease from depression in children and adolescents. More research on the (negative) effects of these interventions is needed.
AD  - Cuijpers,Pim. Dept. of Clinical Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands. p.cuijpers@psy.vu.nl
AN  - 16572276
AU  - Cuijpers,
AU  - P.
AU  - van
AU  - Straten,
AU  - A.
AU  - Smits,
AU  - N.
AU  - Smit,
AU  - F.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-006-0537-4
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
KW  - Adolescent Adult Age Factors Child Depressive Disorder, Major/di [Diagnosis] *Depressive Disorder, Major/ep [Epidemiology] *Depressive Disorder, Major/th [Therapy] Humans *Mass Screening/mt [Methods] *Psychotherapy/mt [Methods] Recurrence *Students/px [
LA  - English
M3  - Meta-Analysis Review
N1  - Cuijpers, Pim van Straten, Annemieke Smits, Niels Smit, Filip
PY  - 2006
SP  - 300-7
T2  - European Child and Adolescent Psychiatry
TI  - Screening and early psychological intervention for depression in schools : systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=16572276 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16572276&amp;id=doi:&amp;issn=1018-8827&amp;isbn=&amp;volume=15&amp;issue=5&amp;spage=300&amp;pages=300-7&amp;date=2006&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=Screening+and+early+psychological+intervention+for+depression+in+schools+%3A+systematic+review+and+meta-analysis.&amp;aulast=Cuijpers&amp;pid=%3Cauthor%3ECuijpers+P%3C%2Fauthor%3E%3CAN%3E16572276%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://download.springer.com/static/pdf/197/art%253A10.1007%252Fs00787-006-0537-4.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-006-0537-4&amp;token2=exp=1435045412~acl=%2Fstatic%2Fpdf%2F197%2Fart%25253A10.1007%25252Fs00787-006-0537-4.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-006-0537-4*~hmac=19aa021d899bd77570db7517c9cb303f4af56385fa3fe6264fe5e1de0286b14f
UR  - https://link.springer.com/article/10.1007%2Fs00787-006-0537-4
VL  - 15
ER  -
TY  - JOUR
AB  - **Background:** 
A large proportion of patients with anxiety disorders fail to respond to first-line medication interventions, despite evidence of the effectiveness of these agents.

**Objectives:** 
To assess the effects of medication versus placebo augmentation in the treatment of patients with anxiety disorders who have failed to respond adequately to first-line drug therapies.

**Search methods:** 
The Cochrane Depression, Anxiety &amp; Neurosis Group (CCDAN) specialised registers (CCDANCTR-Studies and CCDANCTR-References) were searched on 3/8/2005, , MEDLINE (January 1966 to July 2005) and PsycINFO (1966 to 2005, Part A). Unpublished trials were identified through the Controlled Trials database and the National Institute of Health&#039;s Computer Retrieval of Information on Scientific Projects (CRISP) service (1972 to 2005). Additional studies in any language were sought in reference lists of retrieved articles.

**Selection criteria:** 
All randomised controlled trials (RCTs) of the medication augmentation of pharmacotherapy for treatment resistant anxiety disorders.

**Data collection and analysis:** 
Two raters independently assessed RCTs for inclusion in the review, collated trial data, and assessed trial quality. Investigators were contacted to obtain missing data. Summary statistics were stratified by class of augmentation agent and anxiety disorder. Overall effect estimates were calculated using a random-effects model, heterogeneity was assessed and subgroup/sensitivity analyses were undertaken.

**Main results:** 
Twenty eight short-term (average of seven weeks) randomised controlled trials (740 participants) were included in the review, 20 of which investigated augmentation of medication for treatment-resistant obsessive compulsive disorder (OCD). Summary statistics for responder status from nine trials demonstrate overall superiority of a variety of medication agents to placebo (relative risk of non-response (RR) 3.16, 95% CI 1.08 to 9.23). Similarly, symptom severity was significantly reduced in the medication groups, relative to placebo (number of trials (N) = 14, standardised mean difference (SMD) -0.87, 95% CI -1.37 to -0.36). There is no evidence of a difference between medication and placebo in total dropout rate, or in the number of dropouts due to adverse events.

**Authors&#039; conclusions:** 
Medication augmentation can be an effective and well-tolerated short-term treatment strategy for non-responders to first-line pharmacotherapy of anxiety disorders. However, any conclusions must be tentative in view of methodological and clinical heterogeneity, and the fact that much of the relevant database is based on antipsychotic augmentation trials in OCD patients resistant to serotonin reuptake inhibitors (SRIs). Additional data are needed to address several areas, including the efficacy of augmentation over the longer-term, and the value of medication augmentation in comparison to other strategies (eg switching medication, adding psychotherapy).
AN  - CD005473
AU  - Ipser,
AU  - J.
AU  - C.
AU  - Carey,
AU  - P.
AU  - Dhansay,
AU  - Y.
AU  - Fakier,
AU  - N.
AU  - Seedat,
AU  - S.
AU  - Stein,
AU  - D.
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD005473.pub2
KW  - Anti-Anxiety Agents [therapeutic use]
KW  - Anxiety Disorders [drug therapy]
KW  - Drug Synergism
KW  - Drug Therapy, Combination
KW  - Randomized Controlled Trials as Topic
KW  - Treatment Failure
KW  - Humans[checkword]
KW  - Depressn
PY  - 2006
T2  - Cochrane Database of Systematic Reviews
TI  - Pharmacotherapy augmentation strategies in treatment-resistant anxiety disorders
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005473.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005473.pub2/asset/CD005473.pdf?v=1&amp;t=iw7knne4&amp;s=097b4634537758a31931883afc252c38f81d9333
ER  -
TY  - JOUR
AB  - **Background**
Child physical abuse and neglect are important public health problems and recent estimates of their prevalence suggest that they are considerably more common than had hitherto been realised. Many of the risk factors for child abuse and neglect are not amenable to change in the short term. Intervening to change parenting practices may, however, be important in its treatment. Parenting programmes are focused, short-term interventions aimed at improving parenting practices in addition to other outcomes ( many of which are risk factors for child abuse e. g. parental psychopathology, and parenting attitudes and practices), and may therefore be useful in the treatment of physically abusive or neglectful parents. 

**Objectives **
To assess the efficacy of group-based or one-to-one parenting programmes in addressing child physical abuse or neglect. Search strategy A range of biomedical and social science databases were searched including MEDLINE, EMBASE, CINAHL, PsychINFO, Sociofile, Social Science Citation Index, ASSIA, the Cochrane Library, Campbell Library (including SPECTR and CENTRAL), National Research Register (NRR) and ERIC, from inception to May 2005. 

**Selection criteria **
Only randomised controlled trials or randomised studies that compared two treatments were included. Studies had to include at least one standardised instrument measuring some aspect of abusive or neglectful parenting. In the absence of studies using objective assessments of child abuse, studies reporting proxy measures of abusive parenting were included. Only studies evaluating the effectiveness of standardised group-based or one-to-one parenting programmes aimed at the treatment of physical child abuse or neglect were included. Studies were also only eligible for inclusion if they had targeted parents of children aged 0-19 years who had been investigated for physical abuse or neglect. 

**Data collection and analysis **
The treatment effect for each outcome in each study was standardised by dividing the mean difference in post-intervention scores for the intervention and treatment group by the pooled standard deviation, to obtain an effect size. The results for each outcome in each study have been presented, with 95% confidence intervals. It was not possible to combine any results in a meta-analysis. 

**Main results **
A total of seven studies of variable quality were included in this review. Only two studies assessed the effectiveness of parenting programmes on the incidence of child abuse or number of injuries. One study showed that there were no reports of abuse in the intervention group compared with one report of abuse in the control group. In the second study the small number of injuries sustained precluded the possibility of statistical analysis. Data were also extracted on over fifty outcomes that are used as proxy measures of abusive parenting. These were on the whole diverse and measured a range of aspects of parenting (e.g. parental child management, discipline practices, child abuse potential and mental health), child health (e. g. emotional and behavioural adjustment) and family functioning, thereby precluding the possibility of undertaking a meta-analysis for most outcomes for which data were extracted. While none of the programmes were effective across all of the outcomes measured, many appeared to have improved some outcomes for some of the participating parents, although many failed to achieve statistical significance. 

**Authors&#039; conclusions **
There is insufficient evidence to support the use of parenting programmes to treat physical abuse or neglect (i.e. such as the incidence of child abuse using reports of child abuse/injuries or children on the children protection register). There is, however, limited evidence to show that some parenting programmes may be effective in improving some outcomes that are associated with physically abusive parenting. There is an urgent need for further rigorous evaluation of the effectiveness of parenting programmes that are specifically designed to treat physical abuse and neglect, either independently or as rt of broader packages of care. Such evaluation should include the use of objective measures of outcome such as independent assessments of parenting and the number of instances of physical abuse. In order to do this, future studies need to include long-term follow-up.
AD  - Univ Warwick, Warwick Med Sch, Div Hlth Community, Dept Epidemiol &amp; Publ Hlth, Coventry CV4 7AL, W Midlands, England. Barlow, J (reprint author), Univ Warwick, Warwick Med Sch, Div Hlth Community, Dept Epidemiol &amp; Publ Hlth, 108 Med Sch Bldg,Gibbett Hill Campus, Coventry CV4 7AL, W Midlands, England. jane.barlow@warwick.ac.uk
AN  - WOS:000239141400094
AU  - Barlow,
AU  - J.
AU  - Johnston,
AU  - I.
AU  - Kendrick,
AU  - D.
AU  - Polnay,
AU  - L.
AU  - Stewart-Brown,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD005463.pub2
J2  - Cochrane Database Syst Rev.
KW  - AT-RISK EDUCATION-PROGRAM TRAINING-PROGRAM MALTREATMENT FAMILIES METAANALYSIS MANAGEMENT INTERVENTION THERAPY SUPPORT Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 065EE Times Cited: 12 Cited Reference Count: 69 Barlow, J. Johnston, I Kendrick, D. Polnay, L. Stewart-Brown, S. 12 WILEY-LISS HOBOKEN COCHRANE DB SYST REV
PY  - 2006
SP  - 20
T2  - Cochrane Database of Systematic Reviews
TI  - Individual and group-based parenting programmes for the treatment of physical child abuse and neglect
UR  - &lt;Go to ISI&gt;://WOS:000239141400094http://onlinelibrary.wiley.com/store/10.1002/14651858.CD005463.pub2/asset/CD005463.pdf?v=1&amp;t=ib7t4zr5&amp;s=3b89ce71e970480bb07b7d677ce8041226e356af
ER  -
TY  - JOUR
AB  - Background
Independent living programmes (ILPs) are designed to provide young people leaving care with skills that will limit their disadvantage and aid in their successful transition into adulthood. Programmes focus on personal development, independent living skills, education, and vocational support.

Objectives
To assess the effectiveness of independent living programmes for young people leaving the care system.

Search methods
The following electronic databases were searched: Cochrane Register of Controlled Trials (CENTRAL) (Issue 3, 2005); MEDLINE (1966 to June 2005); EMBASE (1980 to June 2005); CINAHL (1982 to June 2005); PsycINFO (1887 to June 2005); Sociological Abstracts (1952 ‐ June 2005); Applied Social Science Index and Abstracts (ASSIA) (1987‐ June 2005) and Dissertation Abstracts (to June 2005). All bibliographies were cross‐referenced, and experts were contacted for unpublished or ongoing studies.

Selection criteria
Randomised or quasi‐randomised controlled trials comparing ILPs to standard care, another intervention, no intervention, or a wait‐list control, for young people leaving care systems at their country&#039;s statutory age of discharge.

Data collection and analysis
2196 citations were identified and screened independently by two reviewers. Full text versions were obtained for 54 papers. None met the review&#039;s inclusion criteria.

Main results
No study was found that met the inclusion criteria of the review. Eighteen studies using nonrandomised or noncomparative designs were found, which generally reported favourable outcomes for ILP participants; however, reliable inferences cannot be drawn from these studies due to their use of weak methodology.

Authors&#039; conclusions
Results from randomised controlled trials show no evidence of the effectiveness of ILPs in improving or impairing outcomes for young people discharged from care. Further research into ILPs using randomised controlled designs is needed.
AU  - Donkoh,
AU  - D.
AU  - Underhill,
AU  - K.
AU  - Montgomery,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2006.8
KW  - Disadvantaged youth
KW  - Social adaptation
KW  - Social welfare
KW  - Adolescents
KW  - Foster care
PY  - 2006
T2  - Cochrane Library
TI  - Independent Living Programmes for Improving Outcomes for Young People Leaving the Care System: A Systematic Review
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Greater dietary intakes of n-3 long-chain polyunsaturated fatty acids (n-3 PUFAs) may be beneficial for depressed mood.

**OBJECTIVE: **
This study aimed to systematically review all published randomized controlled trials investigating the effects of n-3 PUFAs on depressed mood.

**DESIGN: **
Eight medical and health databases were searched over all years of records until June 2006 for trials that exposed participants to n-3 PUFAs or fish, measured depressed mood, were conducted on human participants, and included a comparison group.

**RESULTS: **
Eighteen randomized controlled trials were identified; 12 were included in a meta-analysis. The pooled standardized difference in mean outcome (fixed-effects model) was 0.13 SDs (95% CI: 0.01, 0.25) in those receiving n-3 PUFAs compared with placebo, with strong evidence of heterogeneity (I2 = 79%, P &lt; 0.001). The presence of funnel plot asymmetry suggested that publication bias was the likely source of heterogeneity. Sensitivity analyses that excluded one large trial increased the effect size estimates but did not reduce heterogeneity. Meta-regression provided some evidence that the effect was stronger in trials involving populations with major depression-the difference in the effect size estimates was 0.73 (95% CI: 0.05, 1.41; P = 0.04), but there was still considerable heterogeneity when trials that involved populations with major depression were pooled separately (I2 = 72%, P &lt; 0.001).

**CONCLUSIONS: **
Trial evidence that examines the effects of n-3 PUFAs on depressed mood is limited and is difficult to summarize and evaluate because of considerable heterogeneity. The evidence available provides little support for the use of n-3 PUFAs to improve depressed mood. Larger trials with adequate power to detect clinically important benefits are required.
AD  - Appleton, Katherine M. Department of Experimental Psychology, University of Bristol, Bristol, United Kingdom. k.appleton@qub.ac.uk
AN  - 17158410
AU  - Appleton,
AU  - K.
AU  - M.
AU  - Hayward,
AU  - R.
AU  - C.
AU  - Gunnell,
AU  - D.
AU  - Peters,
AU  - T.
AU  - J.
AU  - Rogers,
AU  - P.
AU  - J.
AU  - Kessler,
AU  - D.
AU  - Ness,
AU  - A.
AU  - R.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
J2  - Am J Clin Nutr
KW  - Adult
KW  - Child
KW  - *Depression/dt [Drug Therapy]
KW  - Depression/ep [Epidemiology]
KW  - *Diet
KW  - Dose-Response Relationship, Drug
KW  - Evidence-Based Medicine
KW  - Fatty Acids, Omega-3/ad [Administration &amp; Dosage]
KW  - *Fatty Acids, Omega-3/tu [Therapeutic Use]
KW  - Female
KW  - Humans
KW  - Male
KW  - *Mood Disorders/dt [Drug Therapy]
KW  - Mood Disorders/ep [Epidemiology]
KW  - Psychometrics
KW  - Randomized Controlled Trials as Topic
KW  - 0 (Fatty Acids, Omega-3)
L1  - internal-pdf://1235084318/Appleton-2006-Effects of n-3 long-chain polyun.pdf
LA  - English
M3  - Meta-Analysis
Research Support, Non-U.S. Gov&#039;t
Review
N1  - Appleton, Katherine MHayward, Robert CGunnell, DavidPeters, Tim JRogers, Peter JKessler, DavidNess, Andrew RComment in: Am J Clin Nutr. 2007 Jun;85(6):1665-6; author reply 1666; PMID: 17556708
PY  - 2006
SP  - 1308-16
T2  - American Journal of Clinical Nutrition
TI  - Effects of n-3 long-chain polyunsaturated fatty acids on depressed mood: systematic review of published trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=17158410
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:17158410&amp;id=doi:&amp;issn=0002-9165&amp;isbn=&amp;volume=84&amp;issue=6&amp;spage=1308&amp;pages=1308-16&amp;date=2006&amp;title=American+Journal+of+Clinical+Nutrition&amp;atitle=Effects+of+n-3+long-chain+polyunsaturated+fatty+acids+on+depressed+mood%3A+systematic+review+of+published+trials.&amp;aulast=Appleton&amp;pid=%3Cauthor%3EAppleton+KM%3C%2Fauthor%3E%3CAN%3E17158410%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://watermark.silverchair.com/znu01206001308.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAa4wggGqBgkqhkiG9w0BBwagggGbMIIBlwIBADCCAZAGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMmfWdixDf47RhaAGjAgEQgIIBYZhErvRvv4cXoXJzxQYiWsGEPpytRPzctw3CoLzZ020cK0BlHVf9OdojUJ-drRJBwTYyE6bpLDkqfQ3Y1vLmabtfdoxP7J-OayIgsxpy3Ejge6bP0KBRk25lnlbwcdirnv8oYlHgplP4Xe56bQA13FLYqT71xycP6F9m-3UEDxqknYJiLxReAkgF7-mPLdOA9Ut_yrTE2GF-vPx6wH_dI8W44qyp08lgGhcal7hbovNc6CV2K1q16DdfiHZmnD-VKncGQdc53Wf0Qf4K1Kzrz9pZsnaQNnTU7thfVoJs_D85CleM4n-TjyUThiyx4hDq3eyfQOzcCs48P4gny5_tjsD02JoF3lYjcJ29m0grkufw28muklpO2o-VuMfU4BvrQomCt8MtEqfHas36a2G7pnWg_Ecg-3Md3NesqVcZBwu-I45gZYSyCRCE7RNlLlljXZIWB9iCqsTcUdD4kFVcOMK7
VL  - 84
ER  -
TY  - JOUR
AB  - **Background:** 
Anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED) and eating disorder not otherwise specified (EDNOS) are common and disabling disorders. Many patients experience difficulties accessing specialist psychological treatments. Pure self-help (PSH: self-help material only) or guided self-help (GSH: self-help material with therapist guidance), may bridge this gap.

**Objectives:** 
Main objective: Evaluate evidence from randomised controlled trials (RCTs) / controlled clinical trials (CCTs) for the efficacy of PSH/GSH with respect to eating disorder symptoms, compared with waiting list or placebo/attention control, other psychological or pharmacological treatments (or combinations/augmentations) in people with eating disorders. Secondary objective: Evaluate evidence for the efficacy of PSH/GSH regarding comorbid symptomatology and costs.

**Search methods:** 
CCDANCTR-Studies and CCDANCTR-References were searched in November 2005, other electronic databases were searched, relevant journals and grey literature were checked, and personal approaches were made to authors.

**Selection criteria:** 
Published/unpublished RCTs/CCTs evaluating PSH/GSH for any eating disorder.

**Data collection and analysis:** 
Data was extracted using a customized spreadsheet. Relative Risks (RR) were calculated from dichotomous data and weighted/standardized mean differences (WMD/SMD) from continuous data, using a random effects model.

**Main results:**
Twelve RCTs and three CCTs were identified, all focusing on BN, BED, EDNOS or combinations of these, in adults, using manual-based PSH/GSH across various settings. Primary comparisons: At end of treatment, PSH/GSH did not significantly differ from waiting list in abstinence from bingeing (RR 0.72, 95% CI 0.47 to 1.09), or purging (RR 0.86, 95% CI 0.68 to 1.08), although these treatments produced greater improvement on other eating disorder symptoms, psychiatric symptomatology and interpersonal functioning but not depression.Compared to other formal psychological therapies, PSH/GSH did not differ significantly at end of treatment or follow-up in improvement on bingeing and purging (RR 0.99, 95% CI 0.75 to 1.31), other eating disorder symptoms, level of interpersonal functioning or depression. There were no significant differences in treatment dropout.Secondary comparisons: One small study in BED found that cognitive-behavioural GSH compared to a non-specific control treatment produced significantly greater improvements in abstinence from bingeing and other eating disorder symptoms. Studies comparing PSH with GSH found no significant differences between treatment groups at end of treatment or follow-up. Comparison between different types of PSH/GSH found significant differences on eating disorder symptoms but not on bingeing/purging abstinence rates.

**Authors&#039; conclusions:** 
PSH/GSH may have some utility as a first step in treatment and may have potential as an alternative to formal therapist-delivered psychological therapy. Future research should focus on producing large well-conducted studies of self-help treatments in eating disorders including health economic evaluations, different types and modes of delivering self-help (e.g. computerised versus manual-based) and different populations and settings.
AN  - CD004191
AU  - Perkins,
AU  - S.
AU  - S.
AU  - J.
AU  - Murphy,
AU  - R.
AU  - R.
AU  - Schmidt,
AU  - U.
AU  - U.
AU  - Williams,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD004191.pub2
KW  - Anorexia Nervosa [therapy]
KW  - Bulimia Nervosa [therapy]
KW  - Controlled Clinical Trials as Topic
KW  - Randomized Controlled Trials as Topic
KW  - Self Care [methods]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2006
T2  - Cochrane Database of Systematic Reviews
TI  - Self-help and guided self-help for eating disorders
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004191.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004191.pub2/asset/CD004191.pdf?v=1&amp;t=iw7l51rn&amp;s=ec1c3cc4b18b0cb94fe4815be7ed11435ebc8346
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
The aim of this study was to assess whether unpublished trials of serotonin reuptake inhibitors in pediatric depression impacted efficacy or safety conclusions, and to examine the evolution of information contributing to the safety/efficacy debate. 

**METHOD: **
From 939 potentially relevant studies extracted from Medline, Cinahl, Biosis, and Cochrane databases, and from the United Kingdom&#039;s Committee on Safety of Medicines website, we examined 38 studies: Ten published and five unpublished randomized, controlled trials, 22 observational studies, and one crossover trial. We performed cumulative and non-cumulative meta-analyses and generated pooled relative rates of response and serious adverse events for high-quality randomized, controlled trials. 

**RESULTS: **
Unpublished studies did not substantially alter the risk-to-benefit determination. Cumulative meta-analyses of seven randomized, controlled trials for efficacy and 11 randomized, controlled trials for safety suggest an adverse safety/efficacy profile for selective serotonin reuptake inhibitors (SSRIs) overall. Fluoxetine and citalopram appear to offer favorable risk to benefit profiles, while shorter-acting agents pose greater risks and provide marginal benefit. 

**CONCLUSIONS: **
While simple meta-analysis across all SSRIs for treatment of pediatric depression provided general efficacy and safety information, meta-analysis of individual drugs and use of cumulative meta-analytic techniques may have expedited our ability to formulate conclusions about safety and efficacy of SSRIs in pediatric depression.
AD  - Wallace,Amy E. Veterans Health Administration, White River Junction, Vermont 05009, USA. amy.e.wallace@dartmouth.edu
AN  - 16553528
AU  - Wallace,
AU  - A.
AU  - E.
AU  - Neily,
AU  - J.
AU  - Weeks,
AU  - W.
AU  - B.
AU  - Friedman,
AU  - M.
AU  - J.
DA  - Feb-Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1089/cap.2006.16.37
DP  - Ovid Technologies
J2  - J Child Adolesc Psychopharmacol
KW  - Adolescent Child *Depressive Disorder, Major/dt [Drug Therapy] Depressive Disorder, Major/ep [Epidemiology] Great Britain Humans Manuscripts as Topic Randomized Controlled Trials as Topic/mt [Methods] *Randomized Controlled Trials as Topic *Serotonin Up
LA  - English
M3  - Meta-Analysis
N1  - Wallace, Amy E Neily, Julia Weeks, William B Friedman, Matthew J
PY  - 2006
SP  - 37-58
T2  - Journal of Child and Adolescent Psychopharmacology
TI  - A cumulative meta-analysis of selective serotonin reuptake inhibitors in pediatric depression: did unpublished studies influence the efficacy/safety debate?
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=16553528 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16553528&amp;id=doi:&amp;issn=1044-5463&amp;isbn=&amp;volume=16&amp;issue=1&amp;spage=37&amp;pages=37-58&amp;date=2006&amp;title=Journal+of+Child+%26+Adolescent+Psychopharmacology&amp;atitle=A+cumulative+meta-analysis+of+selective+serotonin+reuptake+inhibitors+in+pediatric+depression%3A+did+unpublished+studies+influence+the+efficacy%2Fsafety+debate%3F.&amp;aulast=Wallace&amp;pid=%3Cauthor%3EWallace+AE%3C%2Fauthor%3E%3CAN%3E16553528%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://online.liebertpub.com/doi/abs/10.1089/cap.2006.16.37?url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org&amp;rfr_dat=cr_pub%3Dpubmed
VL  - 16
ER  -
TY  - JOUR
AB  - **Background:** 
This is an update of a Cochrane Review first published in The Cochrane Library in Issue 4, 2006.Obsessive-compulsive disorder (OCD) in children and adolescents is characterised by persistent intrusive thoughts, inappropriate impulses or images which cause marked anxiety, and/or by persistent repetitive behaviours such as hand washing, checking and ordering. Along with antidepressant medication, behavioural or cognitive-behavioural therapy (BT/CBT) is recommended as the treatment of choice for paediatric obsessive-compulsive disorder (OCD).

**Objectives:** 
This review examines the overall efficacy of BT/CBT for paediatric OCD, its relative efficacy against medication and whether there are benefits in using BT/CBT combined with medication.

**Search methods:** 
We searched CCDANCTR-Studies,CCDANCTR-References (16/3/2009), MEDLINE, EMBASE, PsycINFO, national trials registers, reference lists of all selected studies and handsearched journals related to cognitive behavioural treatment of OCD.

**Selection criteria:** 
Included studies were randomised or quasi-randomised controlled trials trials with participants 18 years of age or younger with a diagnosis of OCD, established by clinical assessment or standardised diagnostic interview. Reviewed studies included standard behavioural or cognitive-behavioural techniques, either alone or in combination, compared with wait-list, attention placebo, pill placebo or medication.Data collection and analysis: The quality of selected studies was assessed independently by two review authors. Using Review Manager software, weighted mean differences were calculated for the total severity of OCD symptoms at post treatment and relative risks for having OCD at post treatment.

**Main results:** 
Eight studies with 343 participants were included. The review found evidence for lower post-treatment OCD severity and reduced risk of continuing with OCD for the BT/CBT group compared to pill placebo or wait-list comparisons. There was no evidence found that the efficacy of BT/CBT alone and medication alone differ in terms of post treatment symptom severity or in the risk of having OCD. There was some evidence of a benefit for combined BT/CBT and medication compared to medication alone but not relative to BT/CBT alone. The low rates of drop out suggested BT/CBT is an acceptable treatment to child and adolescent patients and their families.

**Authors&#039; conclusions:** 
Although only based on a small number of studies which vary in quality, behavioural or cognitive-behaviour therapy alone appears to be an effective treatment for OCD in children and adolescents. It is as effective as medication alone and may lead to better outcomes when combined with medication compared to medication alone. Additional higher quality trials are needed to confirm these findings.
AN  - CD004856
AU  - O&#039;Kearney,
AU  - R.
AU  - T.
AU  - Anstey,
AU  - K.
AU  - von
AU  - Sanden,
AU  - C.
AU  - Hunt,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004856.pub2
KW  - Behavior Therapy [methods]
KW  - Cognitive Therapy
KW  - Obsessive-Compulsive Disorder [therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2006
T2  - Cochrane Database of Systematic Reviews
TI  - Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004856.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004856.pub2/asset/CD004856.pdf?v=1&amp;t=iw7iwlaj&amp;s=c917f6c684249e39573d3e3c3cae3254de3b0617
ER  -
TY  - JOUR
AB  - The treatment of dually diagnosed adolescents is challenging for many reasons, including complex treatment needs, poor treatment engagement and retention, and a lack of sustainable treatment outcomes. Although a large percentage of adolescents are diagnosed with both substance abuse and mental health diagnoses, research is only beginning to identify effective treatments for this population. The current study systematically reviews randomized clinical trials of interventions for dually diagnosed adolescents. 

Results examining both between-group effect sizes and within group changes indicate the efficacy of several treatment modalities in improving specific aspects of treatment needs but highlight family behavior therapy and individual cognitive problem-solving therapy as showing large effect sizes across externalizing, internalizing, and substance-abuse outcomes in dually diagnosed youth. The study further discusses the complexities of systematically evaluating the currently limited state of research on dually diagnosed youth. Finally, preliminary guidelines for treating dually diagnosed adolescents are derived from a review of those treatments shown to be most effective. (PsycINFO Database Record (c) 2013 APA, all rights reserved) (journal abstract).
AD  - Bender, Kimberly: kbender@mail.utexas.edu Bender, Kimberly: University of Texas at Austin, School of Social Work, 1 University Station D3500, Austin, TX, US, 78712, kbender@mail.utexas.edu Bender, Kimberly: School of Social Work, University of Texas at Austin, Austin, TX, US Springer, David W.: School of Social Work, University of Texas at Austin, Austin, TX, US Kim, Johnny S.: School of Social Welfare, University of Kansas, Lawrence, KS, US
AN  - 2006-10323-001
AU  - Bender,
AU  - K.
AU  - Springer,
AU  - D.
AU  - W.
AU  - Kim,
AU  - J.
AU  - S.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1093/brief-treatment/mhl001
DP  - Ovid Technologies
KW  - treatment effectiveness, dual diagnosis, adolescents, treatment outcomes, substance abuse, mental health problems, interventions *Adolescent Psychiatry *Drug Abuse *Dual Diagnosis *Mental Disorders *Treatment Effectiveness Evaluation Adolescent Developm
LA  - English
M3  - Literature Review
N1  - Special Issue: Evidence-based brief treatment and crisis intervention with co-occurring disorders
PY  - 2006
SP  - 177-205
T2  - Brief Treatment and Crisis Intervention
TI  - Treatment Effectiveness With Dually Diagnosed Adolescents: A Systematic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc5&amp;AN=2006-10323-001 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1093%2Fbrief-treatment%2Fmhl001&amp;issn=1474-3310&amp;isbn=&amp;volume=6&amp;issue=3&amp;spage=177&amp;pages=177-205&amp;date=2006&amp;title=Brief+Treatment+and+Crisis+Intervention&amp;atitle=Treatment+Effectiveness+With+Dually+Diagnosed+Adolescents%3A+A+Systematic+Review.&amp;aulast=Bender&amp;pid=%3Cauthor%3EBender%2C+Kimberly%3C%2Fauthor%3E%3CAN%3E2006-10323-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 6
ER  -
TY  - JOUR
AB  - No abstract available.
AU  - Zief,
AU  - S.
AU  - G.
AU  - Lauver,
AU  - S.
AU  - Maynard,
AU  - R.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2006.3
KW  - Social behaviour
KW  - Emotional development
KW  - Programme evaluation
KW  - Students
KW  - Student activities
KW  - Academic achievement
KW  - Extracurricular activities
PY  - 2006
T2  - Campbell Systematic Reviews
TI  - Impacts of After-School Programs on Student Outcomes: A Systematic Review
ER  -
TY  - JOUR
AB  - **Background:** 
Early aggressive behaviour is a risk factor for later violence and criminal behaviour. Despite over 20 years of violence prevention interventions being delivered in the school setting, questions remain regarding the effectiveness of different interventions for children exhibiting aggressive behaviour.

**Objectives:**
To examine the effect of school based violence prevention programmes for children identified as aggressive or at risk of being aggressive.

**Search methods:** 
We searched CENTRAL, Cochrane Injuries Group specialised register, MEDLINE, EMBASE, other specialised databases and reference lists of articles. We also contacted authors and organisations to identify any further studies.

**Selection criteria:** 
We included trials meeting the following criteria; 1) participants were randomly assigned to intervention and control groups; 2) outcome data were collected concurrently; 3) participants comprised children in mandatory education identified as exhibiting, or at risk of, aggressive behaviour; 4) interventions designed to reduce aggression, violence, bullying, conflict or anger; 5) school based interventions; 6) outcomes included aggressive behaviour, school and agency responses to acts of aggression, or violent injuries.

**Data collection and analysis:** 
Data were collected on design, participants, interventions, outcomes and indicators of study quality. Results of any intervention to no intervention were compared immediately post-intervention and at 12 months using meta-analysis where appropriate.

**Main results:** 
Of 56 trials identified, none reported data on violent injuries. Aggressive behaviour was significantly reduced in intervention groups compared to no intervention groups immediately post intervention in 34 trials with data, (Standardised Mean Difference (SMD) = -0.41; 95% confidence interval (CI) -0.56 to -0.26). This effect was maintained in the seven studies reporting 12 month follow-up (SMD = -0.40, (95% CI -0.73 to -0.06)). School or agency disciplinary actions in response to aggressive behaviour were reduced in intervention groups for nine trials with data, SMD = -0.48; 95% CI -1.16 to 0.19, although this difference may have been due to chance and was not maintained, based on two studies reporting follow-up to two to four months (SMD = 0.03; 95% CI -0.42 to 0.47). Subgroup analyses suggested that interventions designed to improve relationship or social skills may be more effective than interventions designed to teach skills of non-response to provocative situations, but that benefits were similar when delivered to children in primary versus secondary school, and to groups of mixed sex versus boys alone.

**Authors&#039; conclusions:** 
School-based secondary prevention programmes to reduce aggressive behaviour appear to produce improvements in behaviour greater than would have been expected by chance. Benefits can be achieved in both primary and secondary school age groups and in both mixed sex groups and boys-only groups. Further research is required to establish whether such programmes reduce the incidence of violent injuries or if the benefits identified can be maintained beyond 12 months.
AN  - CD004606
AU  - Mytton,
AU  - J.
AU  - A.
AU  - DiGuiseppi,
AU  - C.
AU  - Gough,
AU  - D.
AU  - Taylor,
AU  - R.
AU  - S.
AU  - Logan,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004606.pub2
KW  - Program Evaluation
KW  - Schools
KW  - Adolescent Behavior
KW  - Aggression [psychology]
KW  - Randomized Controlled Trials as Topic
KW  - Social Behavior
KW  - Violence [prevention &amp; control]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Inj
PY  - 2006
T2  - Cochrane Database of Systematic Reviews
TI  - School-based secondary prevention programmes for preventing violence
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004606.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004606.pub2/asset/CD004606.pdf?v=1&amp;t=iw7l4exy&amp;s=22a0ebd9275601b810330b979ee311ceeeeacca2
ER  -
TY  - JOUR
AB  - A meta-analysis of 63 peer-reviewed studies evaluated the ability of parent training programs to modify disruptive child behaviors and parental behavior and perceptions. 

This analysis extends previous work by directly comparing behavioral and nonbehavioral programs, evaluating follow-up effects, isolating dependent variables expressly targeted by parent training, and examining moderators. 

Effects immediately following treatment for behavioral and nonbehavioral programs were small to moderate. For nonbehavioral programs, insufficient studies precluded examining follow-up effects. 

For behavioral programs, follow-up effects were small in magnitude. Parent training was least effective for economically disadvantaged families; importantly, such families benefited significantly more from individually delivered parent training compared to group delivery. Including children in their own therapy, separate from parent training, did not enhance outcomes.
AD  - Lundahl,Brad. College of Social Work, University of Utah, Salt Lake City, UT 84112, USA. Brad.Lundahl@socwk.utah.edu
AN  - 16280191
AU  - Lundahl,
AU  - B.
AU  - Risser,
AU  - H.
AU  - J.
AU  - Lovejoy,
AU  - M.
AU  - C.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1016/j.cpr.2005.07.004
DP  - Ovid Technologies
J2  - Clin Psychol Rev
KW  - Attention Deficit Disorder with Hyperactivity/ep [Epidemiology] Child Child Behavior Disorders/ep [Epidemiology] *Child Behavior Disorders/th [Therapy] Follow-Up Studies Humans *Parents/ed [Education] *Teaching/mt [Methods]
LA  - English
M3  - Meta-Analysis
N1  - Lundahl, Brad Risser, Heather J Lovejoy, M Christine
PY  - 2006
SP  - 86-104
T2  - Clinical Psychology Review
TI  - A meta-analysis of parent training: moderators and follow-up effects
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=16280191 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16280191&amp;id=doi:&amp;issn=0272-7358&amp;isbn=&amp;volume=26&amp;issue=1&amp;spage=86&amp;pages=86-104&amp;date=2006&amp;title=Clinical+Psychology+Review&amp;atitle=A+meta-analysis+of+parent+training%3A+moderators+and+follow-up+effects.&amp;aulast=Lundahl&amp;pid=%3Cauthor%3ELundahl+B%3C%2Fauthor%3E%3CAN%3E16280191%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735805001169/1-s2.0-S0272735805001169-main.pdf?_tid=4fca64fa-1972-11e5-852c-00000aacb35d&amp;acdnat=1435041626_cd8d73c68ece5b6626358df2c0f8be5f
VL  - 26
ER  -
TY  - JOUR
AB  - Meta-analysis was used to examine social, self-concept, and behavioral effects of peer-assisted learning (PAL) interventions with elementary school students. An electronic search of PsycINFO and ERIC databases resulted in 36 relevant PAL studies. Overall, effect sizes were small to moderate across the 3 outcome variable domains. Both social and self-concept outcomes were positively correlated with academic outcomes. Specific PAL components--student autonomy, individualized evaluation, structured student roles, interdependent group rewards, and same-gender grouping--were related to effect sizes. PAL interventions were more effective for low-income versus higher income, urban versus suburban-rural, minority versus nonminority, and Grades 1-3 students versus Grades 4-6 students. Results suggest that PAL interventions that focus on academics can also improve social and self-concept outcomes. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Ginsburg-Block, Marika D.: marika@udel.edu Ginsburg-Block, Marika D.: School of Education, University of Delaware, 205B Willard Hall, Newark, DE, US, 19716, marika@udel.edu Ginsburg-Block, Marika D.: School of Education, University of Delaware, Newark, DE, US Rohrbeck, Cynthia A.: Department of Psychology, George Washington University, Washington, DC, US Fantuzzo, John W.: Graduate School of Education, University of Pennsylvania, PA, US
AN  - 2006-21055-005
AU  - Ginsburg-Block,
AU  - M.
AU  - D.
AU  - Rohrbeck,
AU  - C.
AU  - A.
AU  - Fantuzzo,
AU  - J.
AU  - W.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/0022-0663.98.4.732
DP  - Ovid Technologies
KW  - peer-assisted learning, cooperative learning, peer tutoring, meta-analysis, elementary school students, social outcomes, behavioral outcomes, self-concept *Cooperative Learning *Elementary School Students *Peer Tutoring Psychosocial Development Self Con
LA  - English
M3  - Meta Analysis
PY  - 2006
SP  - 732-749
T2  - Journal of Educational Psychology
TI  - A meta-analytic review of social, self-concept, and behavioral outcomes of peer-assisted learning
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc5&amp;AN=2006-21055-005 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2F0022-0663.98.4.732&amp;issn=0022-0663&amp;isbn=&amp;volume=98&amp;issue=4&amp;spage=732&amp;pages=732-749&amp;date=2006&amp;title=Journal+of+Educational+Psychology&amp;atitle=A+meta-analytic+review+of+social%2C+self-concept%2C+and+behavioral+outcomes+of+peer-assisted+learning.&amp;aulast=Ginsburg-Block&amp;pid=%3Cauthor%3EGinsburg-Block%2C+Marika+D%3C%2Fauthor%3E%3CAN%3E2006-21055-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://psycnet.apa.org/journals/edu/98/4/732.pdf
VL  - 98
ER  -
TY  - JOUR
AB  - **OBJECTIVES:** 
To assess the clinical and cost-effectiveness of oral methylphenidate hydrochloride (MPH), dexamfetaminesulphate (DEX) and atomoxetine (ATX) in children and adolescents (&lt;18 years of age) diagnosed with attention deficit hyperactivity disorder (ADHD) (including hyperkinetic disorder).

**DATA SOURCES:** 
Electronic databases covering 1999--July 2004 for MPH, 1997--July 2004 for DEX and 1981--July 2004 for ATX.

**REVIEW METHODS:** 
Selected studies were assessed using modified criteria based on CRD Report No. 4. Clinical effectiveness data were reported separately for each drug and by the type of comparison. Data for MPH were also analysed separately based on whether it was administered as an immediate release (IR) or extended release (ER) formulation. For all drugs, the data were examined by dose. Data for the core outcomes of hyperactivity (using any scale), Clinical Global Impression [as a proxy of quality of life (QoL)] and adverse events were reported. For crossover studies, the mean and standard deviation (SD) for each outcome were data extracted for end of trial data (i.e. baseline data were not considered). For parallel studies, change scores were reported where given, otherwise means and SDs were presented for end of trial data. In addition, mean differences with 95% confidence intervals were calculated for each study. For adverse events, self-ratings were reported when used, otherwise, parent reports were utilised. Percentages of participants reporting adverse events were used to calculate numbers of events in each treatment arm. All the clinical effectiveness data and economic evaluations (including accompanying models) included in the company submissions were assessed. A new model was developed to assess the cost-effectiveness of the alternative treatments in terms of cost per quality-adjusted life-year. To achieve this, a mixed treatment comparison model was used to estimate the differential mean response rates. Monte Carlo simulation was used to reflect uncertainty in the cost-effectiveness results.RESULTS: In total, 65 papers met the inclusion criteria. The results suggest that MPH and DEX are effective at reducing hyperactivity and improving QoL (as determined by Clinical Global Impression) in children, although the reliability of the MPH study results is not known and there were only a small number of DEX studies. There was consistent evidence that ATX was superior to placebo for hyperactivity and Clinical Global Impression. Studies on ATX more often reported the study methodology well, and the results were likely to be reliable. Very few studies made direct head-to-head comparisons between the drugs or examined a non-drug intervention in combination with MPH, DEX or ATX. Adequate and informative data regarding the potential adverse effects of the drugs were also lacking. The results of the economic evaluation clearly identified an optimal treatment strategy of DEX first-line, followed by IR-MPH for treatment failures, followed by ATX for repeat treatment failures. Where DEX is unsuitable as a first-line therapy, the optimal strategy is IR-MPH first-line, followed by DEX and then ATX. For patients contraindicated to stimulants, ATX is preferred to no treatment. For patients in whom a midday dose of medication is unworkable, ER-MPH is preferred to ATX, and ER-MPH12 appears more cost-effective than ER-MPH8. As identified in the clinical effectiveness review, the reporting of studies was poor, therefore this should be borne in mind when interpreting the model results.

**CONCLUSIONS:**
Drug therapy seems to be superior to no drug therapy, no significant differences between the various drugs in terms of efficacy or side effects were found, mainly owing to lack of evidence, and the additional benefits from behavioural therapy (in combination with drug therapy) are uncertain. Given the lack of evidence for any differences in effectiveness between the drugs, the economic model tended to be driven by drug costs, which differed considerably. Future trials examining MPH, DEX and ATX should include the assessment of tolerability and safety as a priority. Longer term follow-up of individuals participating in trials could further inform policy makers and health professionals. Such data could potentially distinguish between these drugs in a clinically useful way. In addition, research examining whether somatic complaints are actually related to drug treatment or to the disorder itself would be informative. [References: 326]
AD  - King, S. Centre for Reviews and Dissemination, University of York, UK.
AN  - 16796929
AU  - King,
AU  - S.
AU  - Griffin,
AU  - S.
AU  - Hodges,
AU  - Z.
AU  - Weatherly,
AU  - H.
AU  - Asseburg,
AU  - C.
AU  - Richardson,
AU  - G.
AU  - Golder,
AU  - S.
AU  - Taylor,
AU  - E.
AU  - Drummond,
AU  - M.
AU  - Riemsma,
AU  - R.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.3310/hta10230
DP  - Ovid Technologies
J2  - Health Technol Assess
KW  - Adolescent
KW  - Atomoxetine Hydrochloride
KW  - *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy]
KW  - Child
KW  - Child, Preschool
KW  - Cost-Benefit Analysis
KW  - *Dextroamphetamine/tu [Therapeutic Use]
KW  - Humans
KW  - *Methylphenidate/tu [Therapeutic Use]
KW  - *Models, Economic
KW  - *Propylamines/tu [Therapeutic Use]
KW  - Treatment Outcome
KW  - 0 (Propylamines)
KW  - 207ZZ9QZ49 (Methylphenidate)
KW  - 57WVB6I2W0 (Atomoxetine Hydrochloride)
KW  - TZ47U051FI (Dextroamphetamine)
L1  - internal-pdf://3092392090/King.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
Review
Systematic Review
N1  - King, SGriffin, SHodges, ZWeatherly, HAsseburg, CRichardson, GGolder, STaylor, EDrummond, MRiemsma, R
PY  - 2006
SP  - iii-iv, xiii-146
T2  - Health Technology Assessment (Winchester, England)
TI  - A systematic review and economic model of the effectiveness and cost-effectiveness of methylphenidate, dexamfetamine and atomoxetine for the treatment of attention deficit hyperactivity disorder in children and adolescents
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=16796929
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16796929&amp;id=doi:10.3310%2Fhta10230&amp;issn=1366-5278&amp;isbn=&amp;volume=10&amp;issue=23&amp;spage=iii&amp;pages=iii-iv%2C+xiii-146&amp;date=2006&amp;title=Health+Technology+Assessment+%28Winchester%2C+England%29&amp;atitle=A+systematic+review+and+economic+model+of+the+effectiveness+and+cost-effectiveness+of+methylphenidate%2C+dexamfetamine+and+atomoxetine+for+the+treatment+of+attention+deficit+hyperactivity+disorder+in+children+and+adolescents.&amp;aulast=King&amp;pid=%3Cauthor%3EKing+S%3C%2Fauthor%3E%3CAN%3E16796929%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 10
ER  -
TY  - JOUR
AB  - **Background:** 
Many approaches are used to address behavioural problems in childhood including medication or, more usually, psychological treatments either directly with the child and/or his/her family. Behavioural and cognitive-behavioural interventions have been shown to be effective but access to these treatments is limited due to factors such as time and expense. Presenting the information parents need in order to manage these behaviour problems in booklet or other media-based format might reduce the cost and increase access to these interventions.

**Objectives:** 
To review the effects of media-based cognitive-behavioural therapies for any young person with a behavioural disorder (diagnosed using a recognised instrument) compared to standard care and no-treatment controls.

**Search methods:** 
We searched: CENTRAL (The Cochrane Library Issue 3, 2005), MEDLINE (1966 to August 2005), EMBASE (1980 to August 2005), PsycINFO (1887 to August 2005), CINAHL (1982 to August 2005), Biosis (1985 to August 2005) and Sociofile (1974 to August 2005). Bibliographies of all selected trials were checked and experts in the field were contacted for additional information.

**Selection criteria:** 
Randomised and quasi-randomised controlled trials (e.g. trials which used sequential randomisation) of media-based behavioural treatments for behaviour problems in children.

**Data collection and analysis:** 
Abstracts and titles of studies identified from searches of electronic databases were read to determine whether they met the inclusion criteria. Full copies of those possibly meeting these criteria from electronic or other searches were assessed by the reviewers and queries were resolved by discussion. Data were analysed using RevMan 4.2.

**Main results:** 
Eleven studies including 943 participants were included within this review. In general, media-based therapies for behavioural disorders in children had a moderate, if variable, effect when compared with both no-treatment controls with effects sizes ranging from -0.12 (-1.65, 1.41) to -32.60 (-49.93, -15.27) and as and adjunct to medication with effect sizes ranging from -2.71 (-5.86, -0.44) to -39.55 (-75.01, -4.09). Significant improvements were made with the addition of up to two hours of therapist time.

**Authors&#039; conclusions:** 
These formats of delivering behavioural interventions for carers of children are worth considering in clinical practice. Media-based interventions may, in some cases, be enough to make clinically significant changes in a child&#039;s behaviour, and may reduce the amount of time primary care workers have to devote to each case. They can also be used as the first stage of a stepped care approach. Consequently this would increase the number of families who could possibly benefit from these types of intervention, releasing clinician time that can be reallocated to more complex cases. Media-based therapies would therefore appear to have both clinical and economic implications as regards the treatment of children with behavioural problems.
AN  - CD002206
AU  - Montgomery,
AU  - P.
AU  - Bjornstad,
AU  - G.
AU  - J.
AU  - Dennis,
AU  - J.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd002206.pub3
KW  - Adolescent
KW  - Audiovisual Aids
KW  - Bibliotherapy
KW  - Caregivers
KW  - Cognitive Therapy [methods]
KW  - Mental Disorders [therapy]
KW  - Pamphlets
KW  - Patient Education as Topic [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2006
T2  - Cochrane Database of Systematic Reviews
TI  - Media-based behavioural treatments for behavioural problems in children
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002206.pub3/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD002206.pub3/asset/CD002206.pdf?v=1&amp;t=iw7k3fkg&amp;s=c8d32e6a809009fac605649337702b3522ac8642
ER  -
TY  - JOUR
AB  - Extended the findings from previous meta-analytic work by comparing the effectiveness of behavioral parent-training (BPT) and cognitive-behavioral therapy (CBT) for youth with antisocial behavior problems. 

Youth demographic variables were also examined as potential moderators of the effectiveness of these 2 types of interventions. Thirty BPT studies and 41 CBT studies met inclusion criteria for this meta-analysis. 

The weighted mean effect size (ES) for all interventions was 0.40. Youth age was found to moderate the outcome of the 2 interventions, with BPT having a stronger effect for preschool and school-aged youth and CBT having a stronger effect for adolescents. 

The results also indicate that there may be systematic differences in the outcomes associated with BPT and CBT when the setting of the intervention is considered, suggesting the need to carefully consider the effect of setting in future research. 

This study also highlights the need for outcome research dealing with more diverse populations and the better classification of research participants on different developmental trajectories of antisocial behavior.
AD  - McCart,Michael R. Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA. mccartm@musc.edu
AN  - 16838122
AU  - McCart,
AU  - M.
AU  - R.
AU  - Priester,
AU  - P.
AU  - E.
AU  - Davies,
AU  - W.
AU  - H.
AU  - Azen,
AU  - R.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10802-006-9031-1
DP  - Ovid Technologies
J2  - J Abnorm Child Psychol
KW  - Adolescent *Antisocial Personality Disorder/th [Therapy] *Cognitive Therapy/mt [Methods] Humans Models, Psychological *Parent-Child Relations *Parents *Teaching/mt [Methods]
LA  - English
M3  - Meta-Analysis
N1  - McCart, Michael R Priester, Paul E Davies, W Hobart Azen, Razia Comment in: Evid Based Ment Health. 2007 May;10(2):54; PMID: 17459985
PY  - 2006
SP  - 527-43
T2  - Journal of Abnormal Child Psychology
TI  - Differential effectiveness of behavioral parent-training and cognitive-behavioral therapy for antisocial youth: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=16838122
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16838122&amp;id=doi:&amp;issn=0091-0627&amp;isbn=&amp;volume=34&amp;issue=4&amp;spage=527&amp;pages=527-43&amp;date=2006&amp;title=Journal+of+Abnormal+Child+Psychology&amp;atitle=Differential+effectiveness+of+behavioral+parent-training+and+cognitive-behavioral+therapy+for+antisocial+youth%3A+a+meta-analysis.&amp;aulast=McCart&amp;pid=%3Cauthor%3EMcCart+MR%3C%2Fauthor%3E%3CAN%3E16838122%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://link.springer.com/article/10.1007%2Fs10802-006-9031-1
VL  - 34
ER  -
TY  - JOUR
AB  - **Introduction: **
This meta-analysis evaluates the effect of school programs targeting stress management or coping skills in school children.
 
**Methods: **
Articles were selected through a systematic literature search. Only randomized controlled trials or quasi-experimental studies were included. The standardized mean differences (SMDs) between baseline and final measures were computed for experimental and control groups. Experimental groups were groups that either received an intervention of (a) relaxation training, (b) social problem solving, (c) social adjustment and emotional self-control, or (d) a combination of these interventions. If no baseline measurement was available, SMDs were calculated between final measures of the groups. The overall pooled effect size was calculated and the pooled effect sizes of improvement on stress, coping, (social) behavior, and self-efficacy by random effects meta-analysis. The dependence of the results on study characteristics (i.e. methodological quality and type of intervention) was evaluated using meta-regression analysis. 

**Results: **
Nineteen publications met the inclusion criteria of controlled trials for class programs, teaching coping skills or stress management. Overall effect size for the programs was -1.51 [95% confidence interval (CI) -2.29, -0.73], indicating a positive effect. However, heterogeneity was significant ( pb.001). Sensitivity analyses showed that study quality and type of intervention were sources of heterogeneity influencing the overall result (p valuesb.001). The heterogeneity in quality may be associated with methodological diversity and differences in outcome assessments, rather than variety in treatment effect. Effect was calculated per intervention type, and positive effects were found for stress symptoms with a pooled effect size of -0.865 (95% CI: -1.229, -0.502) and for coping with a pooled effect size of -3.493 (95% CI: -6.711, -0.275). 

**Conclusion: **
It is tentatively concluded that school programs targeting stress management or coping skills are effective in reducing stress symptoms and enhancing coping skills. Future research should use clear quality criteria and strive for less diversity in methodology and outcome assessment. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Kraag, Gerda: g.kraag@psychology.unimaas.nl Kraag, Gerda: Department of Experimental Psychology, Maastricht University, P.O. Box 616, Maastricht, Netherlands, 6200 MD, g.kraag@psychology.unimaas.nl Kraag, Gerda: Department of Psychology, Maastricht University, Maastricht, Netherlands Zeegers, Maurice P.: Unit of Genetic Epidemiology, Department of Public Health and Epidemiology, University of Birmingham, Birmingham, United Kingdom Kok, Gerjo: Department of Psychology, Maastricht University, Maastricht, Netherlands Hosman, Clemens: Department of Health Education, Maastricht University, Maastricht, Netherlands Abu-Saad, Huda Huijer: Department School of Nursing, American University of Beirut, Beirut, Lebanon
AN  - 2006-21852-003
AU  - Kraag,
AU  - G.
AU  - Zeegers,
AU  - M.
AU  - P.
AU  - Kok,
AU  - G.
AU  - Hosman,
AU  - C.
AU  - Huijer,
AU  - H.
AU  - Saad,
AU  - A.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jsp.2006.07.001
DP  - Ovid Technologies
KW  - stress management, school programs, coping skills, social problem solving, relaxation training, social adjustment &amp; emotional self control, self efficacy *Coping Behavior *Problem Solving *School Based Intervention *Social Adjustment *Stress Management
LA  - English
M3  - Meta Analysis
PY  - 2006
SP  - 449-472
T2  - Journal of School Psychology
TI  - School programs targeting stress management in children and adolescents: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc5&amp;AN=2006-21852-003 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2Fj.jsp.2006.07.001&amp;issn=0022-4405&amp;isbn=&amp;volume=44&amp;issue=6&amp;spage=449&amp;pages=449-472&amp;date=2006&amp;title=Journal+of+School+Psychology&amp;atitle=School+programs+targeting+stress+management+in+children+and+adolescents%3A+A+meta-analysis.&amp;aulast=Kraag&amp;pid=%3Cauthor%3EKraag%2C+Gerda%3C%2Fauthor%3E%3CAN%3E2006-21852-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0022440506000690/1-s2.0-S0022440506000690-main.pdf?_tid=0a19487e-1678-11e5-ab5d-00000aacb361&amp;acdnat=1434714232_c81cd99d4c31b6f894ea24dcb4b8b378
VL  - 44
ER  -
TY  - JOUR
AB  - **Background:** 
Interventions intended to prevent or reduce use of drugs by young people may be delivered in schools or in other settings. This review aims to summarise the current literature about the effectiveness of interventions delivered in non schools settings.

**Objectives:** 
(1) - To summarise the current evidence about the effectiveness of interventions delivered in non-school settings intended to prevent or reduce drug use by young people under 25; (2) - To investigate whether interventions&#039; effects are modified by the type and setting of the intervention, and the age of young people targeted; (3) - To identify areas where more research is needed.

**Search methods:** 
We searched Cochrane Central Register of Controlled Trials (CENTRAL - The Cochrane Library Issue 4, 2004), MEDLINE (1966-2004), EMBASE (1980-2004), PsycInfo (1972-2004), SIGLE (1980-2004), CINAHL (1982-2004) and ASSIA (1987-2004). We searched also reference lists of review articles and retrieved studies.

**Selection criteria:** 
Randomised trials that evaluated an intervention targeting drug use by young people under 25 years of age, delivered in a non-school setting, compared with no intervention or another intervention, that reported substantive outcomes relevant to the review.

**Data collection and analysis:** 
Two authors independently assessed trial quality and extracted data. Results were tabulated, as studies were considered too dissimilar to combine using meta-analysis.

**Main results:** 
Seventeen studies, 9 cluster randomised studies, with 253 clusters, 8 individually randomised studies with 1230 participants, evaluating four types of intervention: motivational interviewing or brief intervention, education or skills training, family interventions and multi-component community interventions. Many studies had methodological drawbacks, especially high levels of loss to follow-up. There were too few studies for firm conclusions. One study of motivational interviewing suggested that this intervention was beneficial on cannabis use. Three family interventions (Focus on Families, Iowa Strengthening Families Program and Preparing for the Drug-Free Years), each evaluated in only one study, suggested that they may be beneficial in preventing cannabis use. The studies of multi component community interventions did not find any strong effects on drug use outcomes, and the two studies of education and skills training did not find any differences between the intervention and control groups.

**Authors&#039; conclusions:** 
There is a lack of evidence of effectiveness of the included interventions. Motivational interviewing and some family interventions may have some benefit. Cost-effectiveness has not yet been addressed in any studies, and further research is needed to determine whether any of these interventions can be recommended.
AN  - CD005030
AU  - Gates,
AU  - S.
AU  - McCambridge,
AU  - J.
AU  - Smith,
AU  - L.
AU  - A.
AU  - Foxcroft,
AU  - D.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd005030.pub2
KW  - Counseling
KW  - Program Evaluation
KW  - Randomized Controlled Trials as Topic
KW  - Schools
KW  - Substance-Related Disorders [prevention &amp; control]
KW  - Adolescent[checkword]
KW  - Adult[checkword]
KW  - Humans[checkword]
KW  - Addictn
PY  - 2006
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for prevention of drug use by young people delivered in non-school settings
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005030.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005030.pub2/asset/CD005030.pdf?v=1&amp;t=iw7jvf2l&amp;s=f75550435de0138d56300f1b9f6fb180d6c3a2a7
ER  -
TY  - JOUR
AB  - **Introduction: **
The treatment of pediatric aggression often involves psychotropic agents. Despite growing research on pediatric psychopharmacology, however, clinical issues regarding medication management of persistent behavioral problems remain poorly addressed. 

**Method: **
A review of the literature from 1980 to November, 2005 yielded 45 randomized, placebo-controlled trials that addressed the treatment of aggression as either a primary or secondary outcome variable. Effect sizes (ES) (Cohen&#039;s d) were calculated for studies that met inclusion criteria. 

**Results: **
Overall ES for psychotropic agents in treating aggression was 0.56. Despite variability in psychiatric diagnoses, select agents showed moderate to large effects on maladaptive aggression. Most studies focused on younger children (mean age = 10.4 years), and were of short duration (7 to 70 days). Largest effects were noted with methylphenidate for co-morbid aggression in ADHD (mean ES = 0.9, combined n = 844) and risperidone for persistent behavioral disturbances in youth with conduct disorder and sub-average IQ (mean ES = 0.9, combined n = 875). 

**Conclusion: **
A growing literature supports the use of certain medications for managing pediatric aggression. Future studies should distinguish between impulsive and predatory aggression, and examine the efficacy of agents over longer treatment periods.
AD  - (Pappadopulos) Columbia University, College of Physicians and Surgeons, New York, NY, United States (Pappadopulos, Woolston, Chait, Perkins, Jensen) Center for the Advancement of Children&#039;s Mental Health, Columbia University, New York, NY, United States (Connor) University of Connecticut, Health Center, Department of Psychiatry, Farmington, CT, United States E. Pappadopulos, Columbia University, College of Physicians and Surgeons, New York, NY, United States. E-mail: ep2117@columbia.edu
AU  - Pappadopulos,
AU  - E.
AU  - Woolston,
AU  - S.
AU  - Chait,
AU  - A.
AU  - Perkins,
AU  - M.
AU  - Connor,
AU  - D.
AU  - F.
AU  - Jensen,
AU  - P.
AU  - S.
DA  - February
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277275/
KW  - Aggression Effect size Pediatric psychopharmacology age anorexia/si [Side Effect] article ataxia/si [Side Effect] attention deficit disorder/dt [Drug Therapy] autism/dt [Drug Therapy] behavior disorder/dt [Drug Therapy] bipolar disorder/dt [Drug Therapy
KW  - rug Reaction] pemoline magnesium/ct [Clinical Trial] pemoline magnesium/cb [Drug Combination] pemoline magnesium/dt [Drug Therapy] perphenazine/ae [Adverse Drug Reaction] perphenazine/ct [Clinical Trial] perphenazine/dt [Drug Therapy] placebo prolactin/
L1  - internal-pdf://1260760070/Pappadopulos-2006-Pharmacotherapy of aggressio.pdf
LA  - English
PY  - 2006
SP  - 27-39
T2  - Journal of the Canadian Academy of Child and Adolescent Psychiatry
TI  - Pharmacotherapy of aggression in children and adolescents: Efficacy and effect size
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed7&amp;AN=2006177091 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:&amp;id=doi:&amp;issn=1209-7268&amp;isbn=&amp;volume=15&amp;issue=1&amp;spage=27&amp;pages=27-39&amp;date=2006&amp;title=Journal+of+the+Canadian+Academy+of+Child+and+Adolescent+Psychiatry&amp;atitle=Pharmacotherapy+of+aggression+in+children+and+adolescents%3A+Efficacy+and+effect+size&amp;aulast=Pappadopulos&amp;pid=%3Cauthor%3EPappadopulos+E.%3C%2Fauthor%3E%3CAN%3E2006177091%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277275/pdf/ccap15_1p27.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277275/pdf/ccap15_1p27.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Research on the prevention of depressive symptoms in children and adolescents was reviewed and synthesized with meta-analysis. 

When all 30 studies were included, selective prevention programs were found to be more effective than universal programs immediately following intervention. Both selective and indicated prevention programs were more effective than universal programs at follow-up, even when the 2 studies with college students were excluded. 

Effect sizes for selective and indicated prevention programs tended to be small to moderate, both immediately postintervention and at an average follow-up of 6 months. Most effective interventions are more accurately described as treatment rather than prevention.

Suggestions for future research include testing potential moderators (e.g., age, gender, anxiety, parental depression) and mechanisms, designing programs that are developmentally appropriate and gender and culturally sensitive. including longer follow-ups, and using multiple measures and methods to assess both symptoms and diagnoses.
AD  - Vanderbilt Univ, Dept Psychol &amp; Human Dev, Nashville, TN 37203 USA. Horowitz, JL (reprint author), Vanderbilt Univ, Dept Psychol &amp; Human Dev, Peabody 512,230 Appleton Pl, Nashville, TN 37203 USA. jason.horowitz@vanderbilt.edu; garber@vanderbilt.edu
AN  - WOS:000238786700001
AU  - Horowitz,
AU  - J.
AU  - L.
AU  - Garber,
AU  - J.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1037/0022-006X.74.3.401
J2  - J. Consult. Clin. Psychol.
KW  - depression prevention meta-analysis adolescents children COGNITIVE-BEHAVIORAL TREATMENT SCHOOL-BASED PROGRAM MAJOR DEPRESSION RANDOMIZED TRIAL YOUNG ADULTHOOD INTERVENTION CHILDHOOD DISORDER RISK EFFICACY Psychology, Clinical
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 060FB Times Cited: 244 Cited Reference Count: 80 Horowitz, JL Garber, J 249 AMER PSYCHOLOGICAL ASSOC/EDUCATIONAL PUBLISHING FOUNDATION WASHINGTON J CONSULT CLIN PSYCH
PY  - 2006
SP  - 401-415
T2  - Journal of Consulting and Clinical Psychology
TI  - The prevention of depressive symptoms in children and adolescents: A meta-analytic review
UR  - &lt;Go to ISI&gt;://WOS:000238786700001http://psycnet.apa.org/journals/ccp/74/3/401.pdf
VL  - 74
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
To examine whether antidepressant drugs are superior to placebo in the treatment of juvenile depression. 

**METHOD:**
Extensive literature search was done to retrieve all randomised controlled and all uncontrolled trials describing children and adolescents with a diagnosis of depression who underwent any antidepressant drug treatment. In order to combine results, separate analyses using random effect models were conducted first for controlled and then for both controlled and open studies. 

**RESULTS: **
18 controlled and 23 open trials were submitted to meta-analysis. Tricyclics showed no significant benefit over placebo. Odds ratios for SSRIs were 1.84 (95% CI 1.35-2.50) for controlled and 1.83 (95% CI 1.40-2.40) for controlled and uncontrolled studies suggesting a significant benefit over placebo. Combining all antidepressants also gave confidence interval excluding the value one. 

**CONCLUSIONS: **
Despite some promising data concerning the use of SSRIs in the treatment of adolescent depression, caution is warranted until the long-term safety of these agents can be demonstrated. Insufficient data are available to judge even the short term merits of these agents in prepubertal children. There is no evidence to support the use of tricyclics in this population.
AD  - Papanikolaou,K. Department of Child Psychiatry, University of Athens, Agia Sophia Children&#039;s Hospital, Athens, Greece. apechlib@med.uoa.gr
AN  - 16075184
AU  - Papanikolaou,
AU  - K.
AU  - Richardson,
AU  - C.
AU  - Pehlivanidis,
AU  - A.
AU  - Papadopoulou-Daifoti,
AU  - Z.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00702-005-0340-2
DP  - Ovid Technologies
J2  - J Neural Transm
KW  - Adolescent Age Factors *Antidepressive Agents/ad [Administration &amp; Dosage] Antidepressive Agents/ae [Adverse Effects] Antidepressive Agents, Tricyclic/ad [Administration &amp; Dosage] Antidepressive Agents, Tricyclic/ae [Adverse Effects] Child Clinical Tria
LA  - English
M3  - Meta-Analysis
N1  - Papanikolaou, K Richardson, C Pehlivanidis, A Papadopoulou-Daifoti, Z
PY  - 2006
SP  - 399-415
T2  - Journal of Neural Transmission
TI  - Efficacy of antidepressants in child and adolescent depression: a meta-analytic study
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=16075184 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16075184&amp;id=doi:&amp;issn=0300-9564&amp;isbn=&amp;volume=113&amp;issue=3&amp;spage=399&amp;pages=399-415&amp;date=2006&amp;title=Journal+of+Neural+Transmission&amp;atitle=Efficacy+of+antidepressants+in+child+and+adolescent+depression%3A+a+meta-analytic+study.&amp;aulast=Papanikolaou&amp;pid=%3Cauthor%3EPapanikolaou+K%3C%2Fauthor%3E%3CAN%3E16075184%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs00702-005-0340-2http://download.springer.com/static/pdf/528/art%253A10.1007%252Fs00702-005-0340-2.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00702-005-0340-2&amp;token2=exp=1435232881~acl=%2Fstatic%2Fpdf%2F528%2Fart%25253A10.1007%25252Fs00702-005-0340-2.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00702-005-0340-2*~hmac=5ded7dca4fb44af691c8ea34f8a6a4e297b2d16de114287de5548b0203c7f14e
UR  - https://link.springer.com/article/10.1007%2Fs00702-005-0340-2
VL  - 113
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
To develop an evidence base for using antipsychotic medications for schizophrenia in children and adolescents. 

**METHOD: **
Data sources were identified in PsychINFO (1872-2003), MEDLINE (1966-2003), and articles in reference lists. Study selection criteria: (1) treatment with antipsychotics; (2) ages were between 5 and 18 years; (3) sample diagnosed with schizophrenia; (4) prospective design; (5) rating instruments used. Fifteen studies met inclusion criteria and were rated. Study quality was independently rated. 

**RESULTS: **
Average response rate among 8 studies employing atypicals was 55.7% compared to 72.3% among 13 studies employing typicals. The difference was statistically different at the trend level (z = 1.65, P &lt; 0.10). The effect size on a continuous measure was 0.36 in favor of typicals. When study quality was included in the model, the effect of medication type remained unchanged. Average weight gain in patients treated with typicals was 1.4 Kg. compared to 4.5 Kg for those treated with atypicals. Sedation was more common among those on atypicals. The rate of extrapyramidal side effects was similar among the two groups. 

**CONCLUSIONS:** 
Antipsychotic medications seem effective for schizophrenia treatment in children and adolescents. Typicals appear to be more effective and cause less weight gain than atypicals. However, more rigorous clinical trials are necessary.
AD  - Armenteros,Jorge L. New York Psychiatric Institute, New York, NY, USA.
AN  - 16470340
AU  - Armenteros,
AU  - J.
AU  - L.
AU  - Davies,
AU  - M.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1007/s00787-005-0515-2
DP  - Ovid Technologies
J2  - Eur Child Adolesc Psychiatry
KW  - Adolescent Age of Onset *Antipsychotic Agents/tu [Therapeutic Use] Brief Psychiatric Rating Scale Child Child, Preschool Humans Schizophrenia/di [Diagnosis] *Schizophrenia/dt [Drug Therapy] *Schizophrenia/ep [Epidemiology] Severity of Illness Index Trea
L1  - internal-pdf://3177602501/Armenteros-2006-Antipsychotics in early onset.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Armenteros, Jorge L Davies, Mark
PY  - 2006
SP  - 141-8
T2  - European Child and Adolescent Psychiatry
TI  - Antipsychotics in early onset Schizophrenia: Systematic review and meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=16470340 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16470340&amp;id=doi:&amp;issn=1018-8827&amp;isbn=&amp;volume=15&amp;issue=3&amp;spage=141&amp;pages=141-8&amp;date=2006&amp;title=European+Child+%26+Adolescent+Psychiatry&amp;atitle=Antipsychotics+in+early+onset+Schizophrenia%3A+Systematic+review+and+meta-analysis.&amp;aulast=Armenteros&amp;pid=%3Cauthor%3EArmenteros+JL%3C%2Fauthor%3E%3CAN%3E16470340%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://download.springer.com/static/pdf/814/art%253A10.1007%252Fs00787-005-0515-2.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-005-0515-2&amp;token2=exp=1435045402~acl=%2Fstatic%2Fpdf%2F814%2Fart%25253A10.1007%25252Fs00787-005-0515-2.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-005-0515-2*~hmac=0e288364d2d9c0d4368123ea7d31b95e7cee88318fcb9ab277aea13122032186
UR  - http://download.springer.com/static/pdf/814/art%253A10.1007%252Fs00787-005-0515-2.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs00787-005-0515-2&amp;token2=exp=1491227924~acl=%2Fstatic%2Fpdf%2F814%2Fart%25253A10.1007%25252Fs00787-005-0515-2.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs00787-005-0515-2*~hmac=4e0d6669f924b43ffcf44e8fc53efd324c86fcf192cd33f5ec3d58ad198337d8
VL  - 15
ER  -
TY  - JOUR
AB  - **Background:** 
Preterm infants experience a range of morbidity related to the immaturity of their organ systems and to concurrent disease states. There is concern that an unfavourable environment in the neonatal intensive care unit (NICU) may compound this morbidity. Modification of the environment could minimize the iatrogenic effects. Developmental care is a broad category of interventions designed to minimize the stress of the NICU environment. These interventions may include elements such as control of external stimuli (vestibular, auditory, visual, tactile), clustering of nursery care activities, and positioning or swaddling of the preterm infant. Individual strategies have also been combined to form programs, such as the &#039;Newborn Individualized Developmental Care and Assessment Program&#039; (NIDCAP) (Als 1986).

**Objectives:** 
In preterm infants, do developmental care interventions reduce neurodevelopmental delay, poor weight gain, length of hospital stay, length of mechanical ventilation, physiological stress and other clinically relevant adverse outcomes?

**Search methods:** 
The Neonatal Review Group search strategy was utilized. Searches were made of MEDLINE from 1966 to June, 2005 and of CINAHL, The Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, Issue 1, 2005), and conference and symposia proceedings in the English language from 1990 to June, 2005. A search of EMBASE was also made from 2003 to June 2005. A list of all relevant articles was sent to two experts in the field to identify any omissions or additional unpublished studies.

**Selection criteria:** 
Randomized trials in which elements of developmental care are compared to routine nursery care for infants &lt; 37 weeks gestation and that measured clinically relevant outcomes. Reports were in English or a language for which a translator was available.Computerized searches were conducted and all potentially relevant titles and abstracts were extracted. Retrieved articles were assessed for relevance independently by two reviewers, based on predetermined criteria. Articles that met all criteria for relevance were assessed for methodological quality based on predetermined criteria. Articles judged to have the appropriate quality by both reviewers were included in the analysis.

**Data collection and analysis:** 
Data were extracted independently by the two authors. Meta-analyses were conducted for each intervention where the same outcome measures and/or instruments were used within comparable time points.

**Main results:** 
This review detected 36 eligible randomized controlled trials involving four major groups of developmental care interventions, 19 sub-groups and multiple clinical outcomes. In addition, the long-term outcomes of a previously included trial were added to the review.The results of the review indicate that developmental care interventions demonstrate limited benefit to preterm infants with respect to: decreased moderate-severe chronic lung disease, decreased incidence of necrotizing enterocolitis and improved family outcome. Conversely, an increase in mild lung disease and an increase in the length of stay were demonstrated in infants receiving developmental care compared to controls. There is also very limited evidence of the long-term positive effect of NIDCAP on behavior and movement at 5 years corrected age but no effect on cognition. Other individualized developmental care interventions have also demonstrated some effect in enhancing neurodevelopmental outcome. Although a limited number of other benefits were demonstrated, those results were from single studies with small sample sizes. The lack of blinding of the assessors was a significant methodological flaw in half of the studies. The cost of the interventions and personnel was not considered in any of the studies.

**Authors&#039; conclusions:** 
Because of the inclusion of multiple interventions in most studies, the determination of the effect of any single intervention is difficult. Although there is evidence of limited benefit of developmental care interventions overall, and no major harmful ef e ts reported, there were a large number of outcomes for which no or conflicting effects were demonstrated. The single trials that did show a significant effect of an intervention on a major clinical outcome were based on small sample sizes, and the findings were often not supported in other small trials.Before a clear direction for practice can be supported, evidence demonstrating more consistent effects of developmental care interventions on important short- and long-term clinical outcomes is needed. The economic impact of the implementation and maintenance of developmental care practices should be considered by individual institutions.
AN  - CD001814
AU  - Symington,
AU  - A.
AU  - J.
AU  - Pinelli,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd001814
KW  - Infant, Premature
KW  - Developmental Disabilities [prevention &amp; control]
KW  - Environment, Controlled
KW  - Infant, Newborn
KW  - Intensive Care, Neonatal [methods] [standards]
KW  - Length of Stay
KW  - Randomized Controlled Trials as Topic
KW  - Respiration, Artificial
KW  - Stress, Physiological [prevention &amp; control]
KW  - Treatment Outcome
KW  - Weight Gain
KW  - Humans[checkword]
KW  - Neonatal
PY  - 2006
T2  - Cochrane Database of Systematic Reviews
TI  - Developmental care for promoting development and preventing morbidity in preterm infants
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001814.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD001814.pub2/asset/CD001814.pdf?v=1&amp;t=iw7j9a1p&amp;s=c9f9214934674cb1a9a328871bdc46c7ef372bae
ER  -
TY  - JOUR
AB  - **Background **
Depression and anxiety are common psychological disorders for children and adolescents. Psychological ( e. g. psychotherapy), psychosocial (e.g. cognitive behavioral therapy) and biological (e.g. SSRIs or tricyclic drugs) treatments are the most common treatments being offered. The large variety of therapeutic interventions give rise to questions of clinical effectiveness and side effects. Physical exercise is inexpensive with few, if any, side effects. 

**Objectives **
To assess the effects of exercise interventions in reducing or preventing anxiety or depression in children and young people up to 20 years of age. Search strategy We searched the Cochrane Controlled Trials Register (latest issue available), MEDLINE, EMBASE, CINAHL, PsycINFO, ERIC and Sportdiscus up to August 2005. 

**Selection criteria **
Randomised trials of vigorous exercise interventions for children and young people up to the age of 20, with outcome measures for depression and anxiety. 

**Data collection and analysis **
Two authors independently selected trials for inclusion, assessed methodological quality and extracted data. The trials were combined using meta-analysis methods. A narrative synthesis was performed when the reported data did not allow statistical pooling. 

**Main results **
Sixteen studies with a total of 1191 participants between 11 and 19 years of age were included. Eleven trials compared vigourous exercise versus no intervention in a general population of children. Six studies reporting anxiety scores showed a non-significant trend in favour of the exercise group (standard mean difference (SMD) (random effects model) - 0.48, 95% confidence interval (CI) -0.97 to 0.01). Five studies reporting depression scores showed a statistically significant difference in favour of the exercise group (SMD (random effects model) -0.66, 95% CI - 1.25 to -0.08). However, all trials were generally of low methodological quality and they were highly heterogeneous with regard to the population, intervention and measurement instruments used. One small trial investigated children in treatment showed no statistically significant difference in depression scores in favour of the control group (SMD (fixed effects model) 0.78, 95% CI - 0.47 to 2.04). No studies reported anxiety scores for children in treatment. Five trials comparing vigorous exercise to low intensity exercise show no statistically significant difference in depression and anxiety scores in the general population of children. Three trials reported anxiety scores (SMD (fixed effects model) - 0.14, 95% CI - 0.41 to 0.13). Two trials reported depression scores (SMD (fixed effects model) -0.15, 95% CI -0.44 to 0.14). Two small trials found no difference in depression scores for children in treatment (SMD (fixed effects model) -0.31, 95% CI -0.78 to 0.16). No studies reported anxiety scores for children in treatment. Four trials comparing exercise with psychosocial interventions showed no statistically significant difference in depression and anxiety scores in the general population of children. Two trials reported anxiety scores (SMD (fixed effects model) - 0.13, 95% CI - 0.43 to 0.17). Two trials reported depression scores (SMD (fixed effects model) 0.10, 95% CI -0.21 to 0.41). One trial found no difference in depression scores for children in treatment (SMD (fixed effects model) -0.31, 95% CI -0.97 to 0.35). No studies reported anxiety scores for children in treatment. 

**Authors&#039; conclusions **
Whilst there appears to be a small effect in favour of exercise in reducing depression and anxiety scores in the general population of children and adolescents, the small number of studies included and the clinical diversity of participants, interventions and methods of measurement limit the ability to draw conclusions. It makes little difference whether the exercise is of high or low intensity. The effect of exercise for children in treatment for anxiety and depression is unknown as the evidence base is scarce.
AD  - Norwegian Knowledge Ctr Hlth Sci, Dept Knowledge Support, NO-0031 Oslo, Norway. Larun, L (reprint author), Norwegian Knowledge Ctr Hlth Sci, Dept Knowledge Support, POB 7004, NO-0031 Oslo, Norway. lillebeth.larun@nokc.no
AN  - WOS:000239141400054
AU  - Larun,
AU  - L.
AU  - Nordheim,
AU  - L.
AU  - V.
AU  - Ekeland,
AU  - E.
AU  - Hagen,
AU  - K.
AU  - B.
AU  - Heian,
AU  - F.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD004691.pub2
J2  - Cochrane Database Syst Rev.
KW  - PHYSICAL-ACTIVITY AEROBIC EXERCISE HEALTH ADOLESCENTS FITNESS Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 065EE Times Cited: 51 Cited Reference Count: 51 Larun, L. Nordheim, L., V Ekeland, E. Hagen, K. B. Heian, F. 52 WILEY-LISS HOBOKEN COCHRANE DB SYST REV
PY  - 2006
SP  - 42
T2  - Cochrane Database of Systematic Reviews
TI  - Exercise in prevention and treatment of anxiety and depression among children and young people
UR  - &lt;Go to ISI&gt;://WOS:000239141400054http://onlinelibrary.wiley.com/store/10.1002/14651858.CD004691.pub2/asset/CD004691.pdf?v=1&amp;t=ib7tvpx7&amp;s=1a773c3af0edce3f32673379d670dd4ee781bc9d
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To estimate the effectiveness of psychological interventions in pediatric oncology on decreasing psychological distress and increasing psychological adjustment using meta-analytic methods. 

**METHODS: **
A meta-analysis was conducted on 12 psychological intervention studies in pediatric oncology using a weighted least squares (WLS) approach and random effect models. 

**RESULTS: **
Effect sizes significantly different from zero were found for parent distress (mean = 0.35, 95% CI = 0.20-0.49, n = 7) and parent adjustment (mean = 0.23, 95% CI = 0.07-0.40, n = 5). Effect sizes for child distress, child adjustment, parent-reported child distress, and parent-reported child adjustment were not significantly different from zero. 

**CONCLUSIONS: **
Psychological interventions in pediatric oncology show promise in decreasing distress and improving the adjustment of parents of children with cancer but may have minimal effects for child outcomes. Methodological issues of intervention research are discussed.
AD  - Pai,Ahna L H. Rainbow Babies and Children&#039;s Hospital, Case Western Reserve University School of Medicine, USA. paia@email.chop.edu
AN  - 16514049
AU  - Pai,
AU  - A.
AU  - L.
AU  - Drotar,
AU  - D.
AU  - Zebracki,
AU  - K.
AU  - Moore,
AU  - M.
AU  - Youngstrom,
AU  - E.
DA  - Oct
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1093/jpepsy/jsj109
DP  - Ovid Technologies
J2  - J Pediatr Psychol
KW  - Adolescent Child Depressive Disorder, Major/ep [Epidemiology] Depressive Disorder, Major/et [Etiology] Depressive Disorder, Major/th [Therapy] *Depressive Disorder, Major Female Humans Male *Neoplasms/ep [Epidemiology] *Neoplasms/px [Psychology] *Psycho
L1  - internal-pdf://1595677035/Pai-2006-A meta-analysis of the effects of psy.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov&#039;t
N1  - Pai, Ahna L H Drotar, Dennis Zebracki, Kathy Moore, Melisa Youngstrom, Eric
PY  - 2006
SP  - 978-88
T2  - Journal of Pediatric Psychology
TI  - A meta-analysis of the effects of psychological interventions in pediatric oncology on outcomes of psychological distress and adjustment
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=16514049
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16514049&amp;id=doi:&amp;issn=0146-8693&amp;isbn=&amp;volume=31&amp;issue=9&amp;spage=978&amp;pages=978-88&amp;date=2006&amp;title=Journal+of+Pediatric+Psychology&amp;atitle=A+meta-analysis+of+the+effects+of+psychological+interventions+in+pediatric+oncology+on+outcomes+of+psychological+distress+and+adjustment.&amp;aulast=Pai&amp;pid=%3Cauthor%3EPai+AL%3C%2Fauthor%3E%3CAN%3E16514049%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://jpepsy.oxfordjournals.org/content/31/9/978.full.pdf
UR  - https://watermark.silverchair.com/jsj109.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAdgwggHUBgkqhkiG9w0BBwagggHFMIIBwQIBADCCAboGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMn8ie_ezUhtrZ4dvVAgEQgIIBi0r35emjy_Y4FvnyzzHgqwqX6af1B-zhb2BZHwq1CzLXP3br5A4yO9_oe9RrGd72PuK6ENPD-mRVx7Jeh7Tjvjwn7XfyjhQARJT2Wf3HJTdpP1d0mJdE9BXn-MCplpCPElTNO2UQhTMajzPKuNvlPkm1d2QZoyUbnQXe3KlZrGzu6OSLqNAgglKLR24B7PLwkk63r-4FP0oiGkwJcyHXzvsvYcab-ENARnWpPcpVTzQLL2X4yzG9BP9efrGRGo_xJai6viyF7IXQDRtmqjsqjFBDL9r7QzXAUQk58jB9tYvNXKavRBGtFaXhwLhK7ZnWJfp6M0LlNbez5eX6nK2fF9SPo0ieBDBzVTZ-tggQ6ajTnA3GPf7QPILSPMJSCqjSvncaLjPsWZ-hHg4yO0J4ZTf-cGFAXBtx30sShV17hfPq_J1xSm3M4tKlBWRPAaZ65wTUuHG194jlaQjtxtcLvH1DOEsZQygmvDlgDEZHCh2TW3LK_hkljBjgt_-wf6Mbudj8xKlnES2eqwr1
VL  - 31
ER  -
TY  - JOUR
AB  - Fighting, arguments and bullying among school children is a widespread problem. Attempts are often made to counter these social problems by introducing school-based education programmes, which, in one way or another, aim to remedy violent and disruptive behaviour. This systematic review examines one such type of education programme: the type that seeks to strengthen cognitive skills and thought patterns among children to improve their ability to interpret and respond to cues from the world around them (so-called Social Information Processing Interventions). 

The researchers examine two groups of education programmes: those aimed at entire classes and those aimed at selected children who either have behavioural problems or are at risk of developing them. The researchers&rsquo; conclusion is clear: children who participate in this type of education programme exhibit less aggressive and disruptive behaviour than children who do not participate. The positive effect is achieved in both groups in the study, albeit with some variation in the findings: As regards programmes for entire classes, the research indicates that short, intensive interventions &ndash; .g. 8-16 weeks of 2-5 hours a week &ndash; are more effective than extended year-long programmes. Extended programmes may have a tendency to become routine and thus have less impact on the students. Where the education programmes target children in special education classes, the effect is lesser than in ordinary classes. Pupils in special classes may be prone to many other problems which could reduce the impact of this type of education. Conversely, the effect achieved appears to be especially large where the intervention is delivered outside of the regular classroom to children who are at risk for developing later behavioural problems. The researchers maintain that this may be due to the fact that children in the at-risk group have greater change potential. The education programmes in the research review sort under the general concept of Social Information Processing Interventions. This concept embodies a number of different interventions, all of which seek to train children to encode and interpret information and cues in social interaction, and to identify an appropriate response. Through structured exercises and activities, the education is designed to build the children&rsquo;s capacity in respect of one or more of the following six stages: 1. Encoding of own and others&rsquo; cues 2. Interpretation of cues 3. Clarifying a goal 4. Identifying possible responses for achieving the goal 5. Choosing a response 6. Behavioural response enactment The idea is that negative social behaviour, aggression for instance, may be construed as symptomatic of cognitive deficits at one or more of the above stages. The education programmes are designed to remedy these cognitive deficits. Thus, the education focuses on building the children&rsquo;s cognitive skills and thought patterns rather than on directly modifying their behaviour. In this way, these education programmes are distinct from the many different types of behaviour-focused interventions currently practised. By directing attention at thought patterns instead of at behaviour, the aim is to strengthen the children&rsquo;s general social skills. All education programmes in the review were conducted during normal school hours. 

The research review falls into two parts. One part, which examines ordinary classes, is based on 73 individual studies, while the other part, which looks at selected children with behavioural problems or at risk of developing them, is based on 47 studies. Programmes in the first part are delivered to essentially equal numbers of girls and boys aged 4-16. In the second part, the programme participants are primarily boys aged 6 to 16. This difference may be seen as an indication that boys generally make up the majority of pupils exhibiting at-risk or aggressive behaviour. The programmes in the second part also include more children from different ethnic backgrounds than the first part of the research review. Around half of the pupil are from lower socio-economic background families. For both parts, the majority of the studies were conducted in the USA, while studies from Australia, Canada, Italy, Finland, Israel and India were also included. Other research in the area Internationally, a number of social skills studies already exist. However, the majority of these studies address social skills in a more general sense and do not have
AU  - Wilson,
AU  - S.
AU  - J.
AU  - Lipsey,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2006.6
KW  - Programme evaluation
KW  - Children (age group)
KW  - Aggressiveness
KW  - Social information
KW  - Schools
KW  - Schoolchildren
PY  - 2006
T2  - Campbell Systematic Reviews
TI  - The Effects of School-Based Social Information Processing Interventions on Aggressive Behavior: Part II: Selected/Indicated Pull-Out Programs: A Systematic Review
ER  -
TY  - JOUR
AB  - Education programmes may reduce bullying and conflicts among children School-based education programmes aimed at children&rsquo;s ability to interpret social situations may reduce aggressive and disruptive behaviour among children. These are the findings of a systematic Campbell review of the best international research findings in the field. Fighting, arguments and bullying among school children is a widespread problem. Attempts are often made to counter these social problems by introducing school-based education programmes, which, in one way or another, aim to remedy violent and disruptive behaviour. This systematic review examines one such type of education programme: the type that seeks to strengthen cognitive skills and thought patterns among children to improve their ability to interpret and respond to cues from the world around them (so-called Social Information Processing Interventions).The researchers examine two groups of education programmes: those aimed at entire classes and those aimed at selected children who either have behavioural problems or are at risk of developing them. 

The researchers&rsquo; conclusion is clear: children who participate in this type of education programme exhibit less aggressive and disruptive behaviour than children who do not participate. The positive effect is achieved in both groups in the study, albeit with some variation in the findings: 1. As regards programmes for entire classes, the research indicates that short, intensive interventions &ndash; e.g. 8-16 weeks of 2-5 hours a week &ndash; are more effective than extended year-long programmes. Extended programmes may have a tendency to become routine and thus have less impact on the students. 2. Where the education programmes target children in special education classes, the effect is lesser than in ordinary classes. Pupils in special classes may be prone to many other problems which could reduce the impact of this type of education. 3. Conversely, the effect achieved appears to be especially large where the intervention is delivered outside of the regular classroom to children who are at risk for developing later behavioural problems. The researchers maintain that this may be due to the fact that children in the at-risk group have greater change potential. The education programmes in the research review sort under the general concept of Social Information Processing Interventions. This concept embodies a number of different interventions, all of which seek to train children to encode and interpret information and cues in social interaction, and to identify an appropriate response. Through structured exercises and activities, the education is designed to build the children&rsquo;s capacity in respect of one or more of the following six stages: 1. Encoding of own and others&rsquo; cues 2. Interpretation of cues 3. Clarifying a goal 4. Identifying possible responses for achieving the goal 5. Choosing a response 6. Behavioural response enactment The idea is that negative social behaviour, aggression for instance, may be construed as symptomatic of cognitive deficits at one or more of the above stages. The education programmes are designed to remedy these cognitive deficits. Thus, the education focuses on building the children&rsquo;s cognitive skills and thought patterns rather than on directly modifying their behaviour. In this way, these education programmes are distinct from the many different types of behaviour-focused interventions currently practised. By directing attention at thought patterns instead of at behaviour, the aim is to strengthen the children&rsquo;s general social skills. All education programmes in the review were conducted during normal school hours. The research review falls into two parts. One part, which examines ordinary classes, is based on 73 individual studies, while the other part, which looks at selected children with behavioural problems or at risk of developing them, is based on 47 studies. Programmes in the first part are delivered to essentially equal numbers of girls and boys aged 4-16. In the second part, the programme participants are primarily boys aged 6 to 16. This difference may be seen as an indication that boys generally make up the majority of pupils exhibiting at-risk or aggressive behaviour. The programmes in the second part also include more children from different ethnic backgrounds than the first part of the research review. Around half of the pupils are from lower socio-economic background families.For both parts, the majority of the studies were conducted in the USA, while studies from Australia, Canada, Italy, Finland, Israel and India were also included. Internationally, a number of social skills studies already exist. However, the majority of these studies address social skills in a more general sense and do not have the specific focus on education programmes adopted by the present research review.
AU  - Wilson,
AU  - S.
AU  - J.
AU  - Lipsey,
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2006.5
KW  - Programme evaluation
KW  - Children (age group)
KW  - Schoolchildren
KW  - Schools
KW  - Aggressiveness
KW  - Social information
PY  - 2006
T2  - Campbell Systematic Reviews
TI  - The Effects of School-Based Social Information Processing Interventions on Aggressive Behavior: Part I: Universal Programs: A Systematic Review
UR  - http://archive.campbellcollaboration.org/lib/project/14/
ER  -
TY  - JOUR
AB  - Infant disorganized attachment is a major risk factor for problematic stress management and later problem behavior. Can the emergence of attachment disorganization be prevented? 

The current narrative review and quantitative meta-analysis involves 15 preventive interventions (N = 842) that included infant disorganized attachment as an outcome measure. The effectiveness of the interventions ranged from negative to positive, with an overall effect size of d = 0.05 (ns). 

Effective interventions started after 6 months of the infant&#039;s age (d = 0.23). Interventions that focused on sensitivity only were significantly more effective in reducing attachment disorganization (d = 0.24) than interventions that (also) focused on support and parent&#039;s mental representations (d = -0.04). 

Most sample characteristics were not associated with differences in effect sizes, but studies with children at risk were more successful (d = 0.29) than studies with at-risk parents (d = -0.10), and studies on samples with higher percentages of disorganized attachment in the control groups were more effective (d = 0.31) than studies with lower percentages of disorganized children in the control group (d = -0.18). 

The meta-analysis shows that disorganized attachments may change as a side effect of sensitivity-focused interventions, but it also illustrates the need for interventions specifically focusing on the prevention of disorganization. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Bakermans-Kranenburg, Marian J.: bakermans@fsw.leidenuniv.nl Bakermans-Kranenburg, Marian J.: Center for Child and Family Studies, Leiden University, PO Box 9555, Leiden, Netherlands, NL-2300RB, bakermans@fsw.leidenuniv.nl Bakermans-Kranenburg, Marian J.: Leiden University, Leiden, Netherlands Van Ijzendoorn, Marinus H.: Leiden University, Leiden, Netherlands Juffer, Femmie: Leiden University, Leiden, Netherlands
AN  - 2005-05720-002
AU  - Bakermans-Kranenburg,
AU  - M.
AU  - J.
AU  - Van
AU  - Ijzendoorn,
AU  - M.
AU  - H.
AU  - Juffer,
AU  - F.
DA  - May-Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/imhj.20046
DP  - Ovid Technologies
KW  - infant disorganized attachment, preventive interventions, risk factors *Attachment Behavior *Infant Development *Intervention *Parent Child Relations *Prevention Risk Factors Psychosocial &amp; Personality Development [2840] Human
LA  - English
M3  - Literature Review; Meta Analysis
PY  - 2005
SP  - 191-216
T2  - Infant Mental Health Journal
TI  - Disorganized Infant Attachment and Preventive Interventions: A Review and Meta-Analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2005-05720-002 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1002%2Fimhj.20046&amp;issn=0163-9641&amp;isbn=&amp;volume=26&amp;issue=3&amp;spage=191&amp;pages=191-216&amp;date=2005&amp;title=Infant+Mental+Health+Journal&amp;atitle=Disorganized+Infant+Attachment+and+Preventive+Interventions%3A+A+Review+and+Meta-Analysis.&amp;aulast=Bakermans-Kranenburg&amp;pid=%3Cauthor%3EBakermans-Kranenburg%2C+Marian+J%3C%2Fauthor%3E%3CAN%3E2005-05720-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1002/imhj.20046/asset/20046_ftp.pdf?v=1&amp;t=ib3j4kgh&amp;s=b1ee549e5816c93711f801fe8fc8ae05ee1fb7c1
VL  - 26
ER  -
TY  - JOUR
AB  - -
AD  - Hahn,Robert A. Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. Rhahn@cdc.gov
AN  - 15698748
AU  - Hahn,
AU  - R.
AU  - A.
AU  - Bilukha,
AU  - O.
AU  - Lowy,
AU  - J.
AU  - Crosby,
AU  - A.
AU  - Fullilove,
AU  - M.
AU  - T.
AU  - Liberman,
AU  - A.
AU  - Moscicki,
AU  - E.
AU  - Snyder,
AU  - S.
AU  - Tuma,
AU  - F.
AU  - Corso,
AU  - P.
AU  - Schofield,
AU  - A.
AU  - Task
AU  - Force
AU  - on,
AU  - Community
AU  - Preventive
AU  - Services
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.amepre.2004.10.007
DP  - Ovid Technologies
J2  - Am J Prev Med
KW  - Adolescent Advisory Committees Affective Symptoms/th [Therapy] Child Evidence-Based Medicine/mt [Methods] Evidence-Based Medicine/og [Organization &amp; Administration] *Foster Home Care/og [Organization &amp; Administration] *Foster Home Care/sn [Statistics &amp;
LA  - English
M3  - Review
N1  - Hahn, Robert A Bilukha, Oleg Lowy, Jessica Crosby, Alex Fullilove, Mindy T Liberman, Akiva Moscicki, Eve Snyder, Susan Tuma, Farris Corso, Phaedra Schofield, Amanda Task Force on Community Preventive Services
PY  - 2005
SP  - 72-90
T2  - American Journal of Preventive Medicine
TI  - The effectiveness of therapeutic foster care for the prevention of violence: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=15698748
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15698748&amp;id=doi:&amp;issn=0749-3797&amp;isbn=&amp;volume=28&amp;issue=2&amp;spage=72&amp;pages=72-90&amp;date=2005&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=The+effectiveness+of+therapeutic+foster+care+for+the+prevention+of+violence%3A+a+systematic+review.&amp;aulast=Hahn&amp;pid=%3Cauthor%3EHahn+RA%3C%2Fauthor%3E%3CAN%3E15698748%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0749379704002879/1-s2.0-S0749379704002879-main.pdf?_tid=c35ed474-167e-11e5-b1d8-00000aacb35e&amp;acdnat=1434717120_60b604bdb7b4d4ade91b9db4f5fe006e
VL  - 28
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Depression in children and adolescents is a cause of substantial morbidity and mortality in this population. It is a common disorder that affects 2% of children and up to 6% of adolescents. Although antidepressants are used frequently for the treatment of this disorder, there has been recent controversy about the efficacy and safety of these medications in this population. This review examined the available evidence from clinical trials of antidepressants in adolescents and children with depression. 

**METHODS: **
Clinical trial data reviewed were obtained from published reports, including peer review journals and meeting abstracts, as well as unpublished data in the public domain. Clinical trials in this review included large RCTs of antidepressants in youth under the age of 19 with depression. Studies were identified in 2 stages: 1) all RCTs included in the 2004 FDA safety report were reviewed; and 2) to ensure that no additional studies not reported to the FDA were missed, MEDLINE and PSYCH Info were searched from inception until December 2004. A total of 8 published studies and 9 unpublished studies were identified and reviewed. 

**RESULTS: **
Efficacy and safety results from each study are reviewed in detail. There are significant differences in remission and response rates between different antidepressants but also between placebo groups across studies. Adverse events are common in clinical trials involving children and adolescents with depression. Due to lack of access to full data sets, effect sizes could not be calculated. 

**CONCLUSIONS: **
With the variability in trial methodology and the variation in the drug/placebo response rates within a single trial, clinicians need to be judicious in their interpretation of research data on pediatric antidepressant trials. Significant methodological issues may also have affected the efficacy and safety results from these clinical trials.
AD  - Cheung,Amy H. Department of Psychiatry, University of Toronto, Ontario, Canada. Amy_cheung@camh.net
AN  - 15972068
AU  - Cheung,
AU  - A.
AU  - H.
AU  - Emslie,
AU  - G.
AU  - J.
AU  - Mayes,
AU  - T.
AU  - L.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1469-7610.2005.01467.x
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
KW  - Adolescent *Antidepressive Agents/ae [Adverse Effects] *Antidepressive Agents/tu [Therapeutic Use] Antidepressive Agents, Second-Generation/ae [Adverse Effects] Antidepressive Agents, Second-Generation/tu [Therapeutic Use] Bipolar Disorder/ci [Chemicall
LA  - English
M3  - Review
N1  - Cheung, Amy H Emslie, Graham J Mayes, Taryn L
PY  - 2005
SP  - 735-54
T2  - Journal of Child Psychology and Psychiatry and Allied Disciplines
TI  - Review of the efficacy and safety of antidepressants in youth depression
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=15972068 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15972068&amp;id=doi:&amp;issn=0021-9630&amp;isbn=&amp;volume=46&amp;issue=7&amp;spage=735&amp;pages=735-54&amp;date=2005&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Review+of+the+efficacy+and+safety+of+antidepressants+in+youth+depression.&amp;aulast=Cheung&amp;pid=%3Cauthor%3ECheung+AH%3C%2Fauthor%3E%3CAN%3E15972068%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1469-7610.2005.01467.x/asset/j.1469-7610.2005.01467.x.pdf?v=1&amp;t=ib8zyv3s&amp;s=e88a34a4e84b023a777b02d6d900409c40cecf19
VL  - 46
ER  -
TY  - JOUR
AB  - -
AD  - CDCP, Community Guide Branch, Div Unintent Injury Prevent, Natl Ctr Injury Prevent &amp; Control, Atlanta, GA 30341 USA. CDCP, Div Adolescent &amp; Sch Hlth, Natl Ctr Chron Dis Prevent &amp; Hlth Promot, Atlanta, GA 30341 USA. Natl Highway Traff Safety Adm US, Washington, DC 20590 USA. Nichols &amp; Associates, Vienna, VA USA. Elder, RW (reprint author), CDCP, Community Guide Branch, Div Unintent Injury Prevent, Natl Ctr Injury Prevent &amp; Control, 4770 Buford Highway,Mailstop K-95, Atlanta, GA 30341 USA. rfe3@cdc.gov
AN  - WOS:000229379800007
AU  - Elder,
AU  - R.
AU  - W.
AU  - Nichols,
AU  - J.
AU  - L.
AU  - Shults,
AU  - R.
AU  - A.
AU  - Sleet,
AU  - D.
AU  - A.
AU  - Barrios,
AU  - L.
AU  - C.
AU  - Compton,
AU  - R.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.amepre.2005.02.015
J2  - Am. J. Prev. Med.
KW  - ALCOHOL EDUCATION-PROGRAM PREVENTION STUDENTS INTERVENTIONS BEHAVIORS Public, Environmental &amp; Occupational Health Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 929XL Times Cited: 27 Cited Reference Count: 49 Elder, RW Nichols, JL Shults, RA Sleet, DA Barrios, LC Compton, R 27 ELSEVIER SCIENCE INC NEW YORK AM J PREV MED S
PY  - 2005
SP  - 288-304
T2  - American Journal of Preventive Medicine
TI  - Effectiveness of school-based programs for reducing drinking and driving and riding with drinking drivers - A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000229379800007http://ac.els-cdn.com/S0749379705000735/1-s2.0-S0749379705000735-main.pdf?_tid=fa592f2e-167e-11e5-9397-00000aacb362&amp;acdnat=1434717212_e2984c3a19e3e9c0499fbf92d12982da
VL  - 28
ER  -
TY  - JOUR
AB  - **Background:**
Enuresis (bedwetting) is a socially disruptive and stressful condition which affects around 15 to 20% of five year olds, and up to 2% of young adults.

**Objectives:** 
To assess the effects of alarm interventions on nocturnal enuresis in children, and to compare alarms with other interventions.

**Search methods:** 
We searched the Cochrane Incontinence Group Specialised Trials Register (searched 28 February 2007) and the reference lists of relevant articles.Selection criteria: All randomised or quasi-randomised trials of alarm interventions for nocturnal enuresis in children were included, except those focused solely on daytime wetting. Comparison interventions included no treatment, simple and complex behavioural methods, desmopressin, tricyclics, and miscellaneous other methods.

**Data collection and analysis:** 
Two reviewers independently assessed the quality of the eligible trials, and extracted data.

**Main results:** 
Fifty six trials met the inclusion criteria, involving 3257 children of whom 2412 used an alarm. The quality of many trials was poor, and evidence for many comparisons was inadequate. Most alarms used audio methods.Compared to no treatment, about two thirds of children became dry during alarm use (RR for failure 0.38, 95% CI 0.33 to 0.45). Nearly half who persisted with alarm use remained dry after treatment finished, compared to almost none after no treatment (RR of failure or relapse 45 of 81 (55%) versus 80 of 81 (99%), RR 0.56, 95% CI 0.46 to 0.68). There was insufficient evidence to draw conclusions about different types of alarm, or about how alarms compare to other behavioural interventions. Relapse rates were lower when overlearning was added to alarm treatment (RR 1.92, 95% CI 1.27 to 2.92) or if dry bed training was used as well (RR 2.0, 95% CI 1.25 to 3.20). Penalties for wet beds appeared to be counter-productive. Alarms using electric shocks were unacceptable to children or their parents.Although desmopressin may have a more immediate effect, alarms appeared to be as effective by the end of a course of treatment (RR 0.85, 95% CI 0.53 to 1.37) but their relative effectiveness after stopping treatment was unclear from two small trials which compared them directly. Evidence about the benefit of supplementing alarm treatment with desmopressin was conflicting. Alarms were not significantly better than tricyclics during treatment (RR 0.59, 95% CI 0.32 to 1.09) but the relapse rate was less afterwards (7 of 12 (58%) versus 12 of 12 (100%), RR 0.58, 95% CI 0.36 to 0.94). However, other Cochrane reviews of desmopressin and tricyclics suggest that drug treatment alone, while effective for some children during treatment, is unlikely to be followed by sustained cure as almost all the children relapse.

**Authors&#039; conclusions:** 
Alarm interventions are an effective treatment for nocturnal bedwetting in children. Alarms appear more effective than desmopressin or tricyclics because around half the children remain dry after alarm treatment stops. Overlearning (giving extra fluids at bedtime after successfully becoming dry using an alarm), dry bed training and avoiding penalties may further reduce the relapse rate. Better quality research comparing alarms with other treatments is needed, including follow-up to determine relapse rates.
AN  - CD002911
AU  - Glazener,
AU  - C.
AU  - M.
AU  - Evans,
AU  - J.
AU  - H.
AU  - Peto,
AU  - R.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd002911
KW  - Absorbent Pads
KW  - Case-Control Studies
KW  - Deamino Arginine Vasopressin [therapeutic use]
KW  - Electrodes
KW  - Enuresis [drug therapy] [prevention &amp; control]
KW  - Nephrology [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Renal Agents [therapeutic use]
KW  - Child[checkword]
KW  - Child, Preschool[checkword]
KW  - Humans[checkword]
KW  - Incont
PY  - 2005
T2  - Cochrane Database of Systematic Reviews
TI  - Alarm interventions for nocturnal enuresis in children
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002911.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD002911.pub2/asset/CD002911.pdf?v=1&amp;t=iw7imn7b&amp;s=fc9230a123ebcf2e90972b783063a5d6c171b8e9
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To evaluate the effect of iron supplementation on mental and motor development in children through a systematic review of randomised controlled trials (RCTs). 

**DATA SOURCES: **
Electronic databases, personal files, hand search of reviews, bibliographies of books, abstracts and proceedings of international conferences. 

**REVIEW METHODS:**
RCTs with interventions that included oral or parenteral iron supplementation, fortified formula milk or cereals were evaluated. The outcomes studied were mental and motor development scores and various individual development tests employed, including Bayley mental and psychomotor development indices and intelligence quotient. 

**RESULTS: **
The pooled estimate (random effects model) of mental development score standardised mean difference (SMD) was 0.30 (95% confidence interval (CI) 0.15 to 0.46, P&lt;0.001; P&lt;0.001 for heterogeneity). Initial anaemia and iron-deficiency anaemia were significant explanatory variables for heterogeneity. The pooled estimate of Bayley Mental Development Index (weighted mean difference) in younger children (&lt;27 months old) was 0.95 (95% CI -0.56 to 2.46, P=0.22; P=0.016 for heterogeneity). For intelligence quotient scores (&gt; or =8 years age), the pooled SMD was 0.41 (95% CI 0.20 to 0.62, P&lt;0.001; P=0.07 for heterogeneity). There was no effect of iron supplementation on motor development score (SMD 0.09, 95% CI -0.08 to 0.26, P=0.28; P=0.028 for heterogeneity). 

**CONCLUSIONS:**
Iron supplementation improves mental development score modestly. This effect is particularly apparent for intelligence tests above 7 years of age and in initially anaemic or iron-deficient anaemic subjects. There is no convincing evidence that iron treatment has an effect on mental development in children below 27 months of age or on motor development.
AD  - Sachdev,Hps. SL Jain Hospital, New Delhi 110 052, India. hpssachdev@hotmail.com
AN  - 15877905
AU  - Sachdev,
AU  - H.
AU  - Gera,
AU  - T.
AU  - Nestel,
AU  - P.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://doi.org/10.1079/phn2004677
DP  - Ovid Technologies
J2  - Public Health Nutr
KW  - Adolescent Anemia, Iron-Deficiency/co [Complications] *Anemia, Iron-Deficiency/dt [Drug Therapy] Child *Child Development/de [Drug Effects] Child, Preschool *Cognition/de [Drug Effects] Dietary Supplements Female Humans Infant Infant, Newborn Iron/ad [A
L1  - internal-pdf://4105520149/Sachdev-2005-Effect of iron supplementation on.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t Research Support, U.S. Gov&#039;t, Non-P.H.S. Review
N1  - Sachdev, Hps Gera, Tarun Nestel, Penelope
PY  - 2005
SP  - 117-32
T2  - Public Health Nutrition
TI  - Effect of iron supplementation on mental and motor development in children: systematic review of randomised controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=15877905
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15877905&amp;id=doi:&amp;issn=1368-9800&amp;isbn=&amp;volume=8&amp;issue=2&amp;spage=117&amp;pages=117-32&amp;date=2005&amp;title=Public+Health+Nutrition&amp;atitle=Effect+of+iron+supplementation+on+mental+and+motor+development+in+children%3A+systematic+review+of+randomised+controlled+trials.&amp;aulast=Sachdev&amp;pid=%3Cauthor%3ESachdev+H%3C%2Fauthor%3E%3CAN%3E15877905%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://journals.cambridge.org/download.php?file=%2FPHN%2FPHN8_02%2FS1368980005000194a.pdf&amp;code=a982aec414f14ba0954f7b01a59f9543
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/C670976B3D6735E0EE1980B98815D8AF/S1368980005000194a.pdf/div-class-title-effect-of-iron-supplementation-on-mental-and-motor-development-in-children-systematic-review-of-randomised-controlled-trials-div.pdf
VL  - 8
ER  -
TY  - JOUR
AB  - **Background:** 
Asthma is a chronic disease of inflammation and smooth muscle dysfunction, including bronchoconstriction. These symptoms are usually associated with widespread but variable airflow obstruction that is often reversible either spontaneously or with treatment. Psychological factors may influence the symptoms and management of asthma in children in many ways, for example, evidence suggests that emotional stress can either precipitate or exacerbate both acute and chronic asthma.

**Objectives:** 
To assess the efficacy of psychological interventions in improving health and behavioural outcomes for children with asthma.

**Search methods:** 
The Cochrane Airways Group Specialised Register and PsycINFO were searched with pre-defined terms up until April 2007.

**Selection criteria:** 
Randomised controlled trials published in any language assessing the effects of a psychological intervention compared with a control intervention in children and adolescents with asthma were included in the review. Cross-over trials were considered inappropriate for studies using psychological interventions and were therefore excluded from this systematic review.

**Data collection and analysis:** 
Two reviewers assessed the relevance of abstracts identified by electronic searching and retrieved agreed studies for further scrutiny. The studies that met the inclusion criteria were assembled and data extracted.

**Main results:** 
Twelve studies (588 children) were included in the review. Study quality was poor and sample sizes were frequently small. A meta-analysis was possible on two studies only examining the effects of relaxation therapy on PEFR which favoured the treatment group (32 L/min, 95% CI 13 to 50 L/min). No other meta-analysis could be performed due to the diversity of interventions and the outcomes assessed. In addition, many studies reported insufficient data.

**Authors&#039; conclusions:** 
This review was unable to draw firm conclusions for the role of psychological interventions for children with asthma. This review demonstrates the absence of an adequate evidence base and highlights the need for well-conducted and reported randomised trials in this area.
AN  - CD003272
AU  - Yorke,
AU  - J.
AU  - Fleming,
AU  - S.
AU  - L.
AU  - Shuldham,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003272.pub2
KW  - Asthma [psychology] [therapy]
KW  - Behavior Therapy [methods]
KW  - Psychotherapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Relaxation Therapy
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Airways
PY  - 2005
T2  - Cochrane Database of Systematic Reviews
TI  - Psychological interventions for children with asthma
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003272.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003272.pub2/asset/CD003272.pdf?v=1&amp;t=iw7kswit&amp;s=6ebf252eccd3b9ac7df5677b7c948a6dd26a9922
ER  -
TY  - JOUR
AB  - The objective of this review is to summarize the data about metabolic side effects of atypical antipsychotics in children. Original research articles about side effects of atypical antipsychotics used in children were reviewed. 

The data was obtained mainly through Medline searches, identifying articles focusing on the use of atypical antipsychotics in children. Forty studies that addressed the issue of metabolic side effects were selected. The use of atypical antipsychotics in children has been consistently associated with weight gain and moderate prolactin elevation, while only a few case reports address the issue of glucose dysregulation and dyslipidaemia. 

The risk of weight gain and hyperprolactinaemia might be higher in younger children. Other risk factors have also been associated with antipsychotic-induced metabolic disturbances. These changes seem to be reversible, at least in some cases. 

Metabolic side effects of atypical antipsychotics could lead to serious complications in children who are prescribed these medications. Serious considerations should be given before initiating treatment and consistent clinical monitoring is essential. More research is needed, especially regarding glucose dysregulation and dyslipidaemia.
AD  - Fedorowicz,Valerie J. McGill University, Montreal Children&#039;s Hospital, Montreal, QC, Canada H32 1P2.
AN  - 16166191
AU  - Fedorowicz,
AU  - V.
AU  - J.
AU  - Fombonne,
AU  - E.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/0269881105056543
DP  - Ovid Technologies
J2  - J Psychopharmacol
KW  - Adolescent *Antipsychotic Agents/ae [Adverse Effects] Antipsychotic Agents/tu [Therapeutic Use] Attention Deficit and Disruptive Behavior Disorders/dt [Drug Therapy] Child Child Behavior Disorders/dt [Drug Therapy] Humans *Metabolic Diseases/ci [Chemica
LA  - English
M3  - Meta-Analysis Review
N1  - Fedorowicz, Valerie J Fombonne, Eric
PY  - 2005
SP  - 533-50
T2  - Journal of Psychopharmacology
TI  - Metabolic side effects of atypical antipsychotics in children: a literature review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=16166191 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16166191&amp;id=doi:&amp;issn=0269-8811&amp;isbn=&amp;volume=19&amp;issue=5&amp;spage=533&amp;pages=533-50&amp;date=2005&amp;title=Journal+of+Psychopharmacology&amp;atitle=Metabolic+side+effects+of+atypical+antipsychotics+in+children%3A+a+literature+review.&amp;aulast=Fedorowicz&amp;pid=%3Cauthor%3EFedorowicz+VJ%3C%2Fauthor%3E%3CAN%3E16166191%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://jop.sagepub.com/content/19/5/533.full.pdf
UR  - http://journals.sagepub.com/doi/abs/10.1177/0269881105056543?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 19
ER  -
TY  - JOUR
AB  - **Background:** 
The use of mega-vitamin intervention began in the 1950s with the treatment of schizophrenic patients. Pyroxidine (vitamin B6) was first used with children diagnosed with &quot;autism syndrome&quot; when speech and language improvement was observed in some children as a result of large doses of B6. A number of studies attempted to assess the effects of vitamin B6-Magnesium (Mg) was found to reduce undesirable side effects from B6) on characteristics such as verbal communication, non-verbal communication, interpersonal skills, and physiological function, in individuals with autism.

**Objectives:** 
To determine the efficacy of vitamin B6 and magnesium (B6-Mg) for treating social, communication, and behavioural responses of children and adults with autism.Search methods: We searched the Cochrane Controlled Trials Register (Cochrane Library, Issue 1, 2005), MEDLINE (1966 to April 2005), EMBASE (1980 to April 2005), PsycINFO (1887 to April 2005), Dissertation Abstracts International (1861 to April 2005). The search engine FirstSearch was also used (April 2005). Reference lists for all the obtained studies and other review articles were examined for additional studies.

**Selection criteria:** 
All studies in which the participants had been diagnosed with autistic spectrum disorder were randomly allocated prior to intervention and in which outcomes were compared to either a placebo or non-treated group were included.

**Data collection and analysis:** 
Two reviewers independently evaluated and extracted data from all potential studies identified for inclusion.

**Main results:** The 2005 update includes a new trial (Kuriyama 2002) to bring the total of included studies to three (total n=33). One study, which used a cross-over design (Tolbert 1993) provided insufficient data to conduct an analysis. Another crossover study (Findling 1997) yielded no significant differences between treatment and placebo group performances following the B6 intervention on measures of social interaction, communication, compulsivity, impulsivity, or hyperactivity. The latest study (Kuriyama 2002) was motivated by evidence from epilepsy research and was focussed on a subgroup of children with pervasive developmental disorders (PDDs) who exhibited clinical features similar to those with pyroxidine-dependent epilepsy. This small study (n=8) only measured IQ and &#039;Social Quotient&#039; and found a statistically significant benefit for IQ (5.2, 95% CI = [0.2 to 10.3]) when in the treated group, by using change scores.

**Authors&#039; conclusions:** 
Due to the small number of studies, the methodological quality of studies, and small sample sizes, no recommendation can be advanced regarding the use of B6-Mg as a treatment for autism.
AN  - CD003497
AU  - Nye,
AU  - C.
AU  - Brice,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003497
KW  - Autistic Disorder [drug therapy]
KW  - Drug Therapy, Combination
KW  - Magnesium [therapeutic use]
KW  - Randomized Controlled Trials as Topic
KW  - Vitamin B 6 [therapeutic use]
KW  - Vitamin B Complex [therapeutic use]
KW  - Adult[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2005
T2  - Cochrane Database of Systematic Reviews
TI  - Combined vitamin B6-magnesium treatment in autism spectrum disorder
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003497.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003497.pub2/asset/CD003497.pdf?v=1&amp;t=iw7j6f56&amp;s=ac7eecc9c8857375898a296f11d50af35c55c7a1
ER  -
TY  - JOUR
AB  - This paper reviews the international scientific evidence on the effectiveness of secondary prevention interventions for young drug users. The review provides insight into the effectiveness of interventions that have been evaluated using moderately strong research designs. 

Most of the studies included are from the-United States of America. Some interventions are effective in reducing drug use and associated problems while others have no or mixed effect. Those successful in reducing drug use include behavior therapy, Minnesota 12-step programs, residential care, and general drug treatment. 

Those with either no effect or mixed effect include schools interventions. Involving parents and other agencies may enhance an intervention&#039;s effect. There is a lack of good quality studies outside the USA. 

Future interventions should focus on either low- or high-risk groups of young drug users. Future research should be conducted on a wider range of services for young people and include non-medical outcomes such as communication skills, schooling, employment, family relations, and economic costs.
AD  - Univ Dundee, Sch Nursing &amp; Midwifery, Dundee DD1 4HJ, Scotland. Elliott, L (reprint author), Univ Dundee, Sch Nursing &amp; Midwifery, 11 Airlie Pl, Dundee DD1 4HJ, Scotland. l.elliott@dundee.ac.uk
AN  - WOS:000227962900001
AU  - Elliott,
AU  - L.
AU  - Orr,
AU  - L.
AU  - Watson,
AU  - L.
AU  - Jackson,
AU  - A.
DA  - Spr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Har ikke DOI. Link: https://www.ncbi.nlm.nih.gov/pubmed/15861614
J2  - Adolescence
KW  - ADOLESCENT SUBSTANCE-ABUSE RANDOMIZED CLINICAL-TRIALS VULNERABLE GROUPS RISK-FACTORS CANNABIS USE QUALITY GUIDES YOUTH THERAPY SCHOOL Psychology, Developmental
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 910WM Times Cited: 4 Cited Reference Count: 37 Elliott, L Orr, L Watson, L Jackson, A 4 LIBRA PUBLISHERS INC SAN DIEGO ADOLESCENCE
PY  - 2005
SP  - 1-22
T2  - Adolescence
TI  - Secondary prevention interventions for young drug users: A systematic review of the evidence
UR  - &lt;Go to ISI&gt;://WOS:000227962900001http://media.proquest.com/media/pq/classic/doc/821252351/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Elliott%2C+Lawrence%3BOrr%2C+Linda%3BWatson%2C+Lynsey%3BJackson%2C+Andrew&amp;cit%3Atitle=SECONDARY+PREVENTION+INTERVENTIONS+FOR+YOUNG+DRUG+USERS%3A+A+SYSTEMATIC+REVIEW+OF+THE+EVIDENCE&amp;cit%3Apub=Adolescence&amp;cit%3Avol=40&amp;cit%3Aiss=157&amp;cit%3Apg=1&amp;cit%3Adate=Spring+2005&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYxOTEwMzYyOTY3Njo2NjQ1NzgSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNDE1MzkyCTE5NTk0NDAyMzoNRG9jdW1lbnRJbWFnZUIBMFIGT25saW5lWgJGVGIDUEZUagoyMDA1LzA0LzAxcgoyMDA1LzA2LzMwegCCASlQLTEwMDAyNzMtMzEwNzUtQ1VTVE9NRVItMTAwMDAxNTctMTExNTExMpIBBk9ubGluZcoBB0VuZE5vdGXSARJTY2hvbGFybHkgSm91cm5hbHOaAgdQcmVQYWlkqgIoT1M6RU1TLVBkZkRvY1ZpZXdCYXNlLWdldE1lZGlhVXJsRm9ySXRlbcoCB0FydGljbGXSAgFZ4gIBTvICAA%3D%3D&amp;_s=jWhWl7tEW5oi4ALqqTMpfUCuxLM%3D
VL  - 40
ER  -
TY  - JOUR
AB  - **OBJECTIVES:** 
To assess the clinical and cost-effectiveness of parent training programmes for the treatment of children with conduct disorder (CD) up to the age of 18 years.

**DATA SOURCES:** 
Electronic databases.

**REVIEW METHODS:** 
For the effectiveness review, relevant studies were identified and evaluated. A quantitative synthesis of behavioural outcomes across trials was also undertaken using two approaches: vote counting and meta-analysis. The economic analysis consisted of reviewing previous economic/cost evaluations of parent training/education programmes and the economic information within sponsor&#039;s submissions; carrying out a detailed exploration of costs of parent training/education programmes; and a de novo modelling assessment of the cost-effectiveness of parent training/education programmes. The potential budget impact to the health service of implementing such programmes was also considered.

**RESULTS:** 
Many of the 37 randomised controlled trials that met the review inclusion and exclusion criteria were assessed as being of poor methodological quality. Studies were clinically heterogeneous in terms of the population, type of parent training/education programme and content, setting, delivery, length and child behaviour outcomes used. Both vote counting and meta-analysis revealed a consistent trend across all studies towards short-term effectiveness (up to 4 months) of parent training/education programmes (compared with control) as measured by a change in child behaviour. Pooled estimates showed a statistically significant improvement on the Eyberg Child Behaviour Inventory frequency and intensity scales, the Dyadic Parent-Child Interaction Coding System and the Child Behaviour Checklist. No studies reported a statistically significant result favouring control over parent training/education programmes. There were few statistically significant differences between different parent training/education programmes, although there was a trend towards more intensive interventions (e.g. longer contact hours, additional child involvement) being more effective. The cost of treating CD is high, with costs incurred by many agencies. A recent study suggested that by age 28, costs for individuals with CD were around 10 times higher than for those with no problems, with a mean cost of 70,019 pounds sterling. Criminality incurs the greatest cost, followed by educational provision, foster and residential care and state benefits. Only a small proportion of these costs fall on health services. Using a &#039;bottom-up&#039; costing approach, the costs per family of providing parent training/education programmes range from 629 pounds sterling to 3839 pounds sterling depending on the type and style of delivery. Using the conservative assumption that there are no cost savings from treatment, a total lifetime quality of life gain of 0.1 would give a cost per quality-adjusted life-year of between 38,393 pounds sterling and 6288 pounds sterling depending on the type of programme delivery and setting.

**CONCLUSIONS:** 
Parent training/education programmes appear to be an effective and potentially cost-effective therapy for children with CD. However, the relative effectiveness and cost-effectiveness of different models (such as therapy intensity and setting) require further investigation. Further research is required on the impact of parent training/education programmes on the quality of life of children with CD and their parents/carers, as well as on longer term child outcomes. [References: 124]
AD  - Dretzke, J. West Midlands Health Technology Assessment Collaboration, Department of Public Health and Epidemiology, University of Birmingham, UK.
AN  - 16336845
AU  - Dretzke,
AU  - J.
AU  - Frew,
AU  - E.
AU  - Davenport,
AU  - C.
AU  - Barlow,
AU  - J.
AU  - Stewart-Brown,
AU  - S.
AU  - Sandercock,
AU  - J.
AU  - Bayliss,
AU  - S.
AU  - Raftery,
AU  - J.
AU  - Hyde,
AU  - C.
AU  - Taylor,
AU  - R.
DA  - Dec
DB  - Rekoding IN SUM_lme.enl
DO  - 10.3310/hta9500
DP  - Ovid Technologies
J2  - Health Technol Assess
KW  - Adolescent
KW  - Child
KW  - *Conduct Disorder/th [Therapy]
KW  - Cost-Benefit Analysis
KW  - Humans
KW  - *Parents/ed [Education]
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://2073240551/Dretzke.pdf
LA  - English
M3  - Review
N1  - Dretzke, JFrew, EDavenport, CBarlow, JStewart-Brown, SSandercock, JBayliss, SRaftery, JHyde, CTaylor, R
PY  - 2005
SP  - iii, ix-x, 1-233
T2  - Health Technology Assessment (Winchester, England)
TI  - The effectiveness and cost-effectiveness of parent training/education programmes for the treatment of conduct disorder, including oppositional defiant disorder, in children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=16336845
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16336845&amp;id=doi:10.3310%2Fhta9500&amp;issn=1366-5278&amp;isbn=&amp;volume=9&amp;issue=50&amp;spage=iii&amp;pages=iii%2C+ix-x%2C+1-233&amp;date=2005&amp;title=Health+Technology+Assessment+%28Winchester%2C+England%29&amp;atitle=The+effectiveness+and+cost-effectiveness+of+parent+training%2Feducation+programmes+for+the+treatment+of+conduct+disorder%2C+including+oppositional+defiant+disorder%2C+in+children.&amp;aulast=Dretzke&amp;pid=%3Cauthor%3EDretzke+J%3C%2Fauthor%3E%3CAN%3E16336845%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 9
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
Treatment for childhood nocturnal enuresis emphasizes either a psychological or pharmacological approach. The enuresis alarm, in comparative studies, has emerged as the most effective psychological treatment. In this review we investigate both outcome rates and influential factors from recently published studies. 

**MATERIAL AND METHODS: **
A search of papers published between 1980 and 2002 in the English language involving at least 10 children in which the enuresis alarm was employed as a stand-alone intervention revealed 38 studies. 

**RESULTS: **
Heterogeneity in terms of inclusion and outcome parameters made comparison between studies problematic. The most frequently adopted definitions were &quot;wet at least 3 times a week&quot; in terms of severity at inclusion, &quot;14 consecutive dry nights&quot; as a success criterion and &quot;&gt; 1 wet night a week&quot; as a relapse criterion. Success rates across all studies ranged from 30% to 87% and were influenced by the type of enuresis, the treatment duration and the success criteria adopted. In an homogenous subset of 20 studies, 65% success with alarm treatment was found. Further analysis revealed equivalence between different forms of alarm, pre- and within-treatment predictors of outcome and possible mode of action. Relapse rates (ranging between 4% and 55%) were reported in 20 studies, with an homogeneous subset indicating that 42% of children relapsed following alarm treatment. 

**CONCLUSIONS:**
The enuresis alarm is an effective intervention for children with nocturnal enuresis. There are a number of factors, both pre- and within-treatment, that appear to influence its effectiveness and may assist clinical decisions concerning its appropriateness for any particular child.
AD  - Butler,Richard J. Clinical Psychology Department, Child and Adolescent Mental Health Services, East Leeds Primary Care Trust, Leeds, UK. richard.butler@leedsmh.nhs.uk
AN  - 16257835
AU  - Butler,
AU  - R.
AU  - J.
AU  - Gasson,
AU  - S.
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/00365590500220321
DP  - Ovid Technologies
J2  - Scand J Urol Nephrol
KW  - *Behavior Therapy/mt [Methods] Circadian Rhythm Enuresis/pp [Physiopathology] *Enuresis/th [Therapy] Humans Treatment Outcome
L1  - internal-pdf://2693216896/Butler-2005-Enuresis alarm treatment.pdf
LA  - English
M3  - Review
N1  - Butler, Richard J Gasson, Sarah L
PY  - 2005
SP  - 349-57
T2  - Scandinavian Journal of Urology and Nephrology
TI  - Enuresis alarm treatment
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=16257835 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16257835&amp;id=doi:&amp;issn=0036-5599&amp;isbn=&amp;volume=39&amp;issue=5&amp;spage=349&amp;pages=349-57&amp;date=2005&amp;title=Scandinavian+Journal+of+Urology+%26+Nephrology&amp;atitle=Enuresis+alarm+treatment.&amp;aulast=Butler&amp;pid=%3Cauthor%3EButler+RJ%3C%2Fauthor%3E%3CAN%3E16257835%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://informahealthcare.com/doi/pdfplus/10.1080/00365590500220321
UR  - http://www.tandfonline.com/doi/pdf/10.1080/00365590500220321?needAccess=true
VL  - 39
ER  -
TY  - JOUR
AB  - Although it is generally believed that early intervention programmes are an effective means to stimulate children&#039;s cognitive development, many questions remain concerning programme design and delivery. This article reviews 19 studies into the effectiveness of early intervention programmes published from 1985 onward. The database comprised 85 different outcomes or effect sizes (71 in the cognitive domain, 14 in the socioemotional domain). The overall effect size estimate was d = 0.32 (SE = 0.05) in the cognitive domain, and d = 0.05 (SE = 0.02) in the socioemotional domain. Effect sizes were found to depend on delivery mode. Centre-based interventions and interventions following the combined home- and centre-based delivery mode produced greater effect sizes than did home-based programmes in the cognitive domain, but not in the socioemotional domain. The programme inclusion of coaching of parenting skills was also positively related to outcomes in the cognitive domain. Several other programme characteristics, including age of onset, programme length and intensity, continuation after kindergarten, and the inclusion of social or economic support, appeared not to be uniquely related to outcomes. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - M Blok, Henk: H.Blok@uva.nl Blok, Henk: University of Amsterdam, Faculty of Social and Behavioral Sciences, SCO-Kohnstamm Instituut, Wibautstraat 4, Amsterdam, Netherlands, 1091 GM, H.Blok@uva.nl Blok, Henk: University of Amsterdam, Amsterdam, Netherlands Fukkink, Ruben G.: University of Amsterdam, Amsterdam, Netherlands Gebhardt, Eveline C.: University of Amsterdam, Amsterdam, Netherlands Leseman, Paul P. M.: University of Amsterdam, Amsterdam, Netherlands
AN  - 2004-21893-004
AU  - Blok,
AU  - H.
AU  - Fukkink,
AU  - R.
AU  - G.
AU  - Gebhardt,
AU  - E.
AU  - C.
AU  - Leseman,
AU  - P.
AU  - P.
AU  - M.
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/01650250444000315
DP  - Ovid Technologies
KW  - early childhood intervention, cognitive development, parenting skills, socioemotional domain, early intervention programmes *Cognitive Development *Early Childhood Development *Early Intervention Parenting Skills Developmental Psychology [2800] Human
LA  - English
M3  - Meta Analysis
PY  - 2005
SP  - 35-47
T2  - International Journal of Behavioral Development
TI  - The relevance of delivery mode and other programme characteristics for the effectiveness of early childhood intervention
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2004-21893-004
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F01650250444000315&amp;issn=0165-0254&amp;isbn=&amp;volume=29&amp;issue=1&amp;spage=35&amp;pages=35-47&amp;date=2005&amp;title=International+Journal+of+Behavioral+Development&amp;atitle=The+relevance+of+delivery+mode+and+other+programme+characteristics+for+the+effectiveness+of+early+childhood+intervention.&amp;aulast=Blok&amp;pid=%3Cauthor%3EBlok%2C+Henk%3C%2Fauthor%3E%3CAN%3E2004-21893-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://jbd.sagepub.com/content/29/1/35http://jbd.sagepub.com/content/29/1/35.full.pdf
VL  - 29
ER  -
TY  - JOUR
AB  - **Objectives:** 
To synthesize the extant empirical evidence on the effects of boot-camps and boot camp like programs on the criminal behavior (e.g., postrelease arrest, conviction, or reinstitutionalization) of convicted adult and juvenile offenders. 

**Search Strategy:**
Numerous electronic databases were searched for both published an unpublished studies. The keywords used were: boot camp(s), intensive incarceration, and shock incarceration. We also contacted .S and non-U.S. researchers working in this area requesting assistance in locating additional studies. The final search of these sources was completed in early December of 2003. 

**Selection Criteria:**
The eligibility criteria were (a) that the study evaluated a correctional boot camp, shock incarceration, or intensive incarceration program; (b) that the study included a comparison group that received either probation or incarceration in an alternative facility; (c) that the study participants were exclusively under the supervision of the criminal or juvenile justice system; and (d) that the study reported a post-program measure of criminal behavior, such as arrest or conviction. 

**Data Collection and Analysis:**
The coding protocol captured aspects of the research design, including methodological quality, the boot-camp program, the comparison group condition, the participant offenders, the outcome measures and the direction and magnitude of the observed effects. All studies were coded by two independent coders and all coding differences were resolved by Drs. MacKenzie or Wilson. Outcome effects were coded using the odds-ratio and meta-analysis was performed using the random effects model. 

**Main Results:**
Thirty-two unique research studies met our inclusion criteria. These studies reported the results from 43 independent boot-camp/comparison samples. The random effects mean odds-ratio for any form of recidivism was 1.02, indicating that the likelihood that boot camp participants recidivating Effects of Correctional Boot Camps 3 was roughly equal to the likelihood of comparison participants recidivating. This overall finding was robust to the selection of the outcome measure and length of follow-up. Methodological features were only weakly related to outcome among these studies and did not explain the null findings. The overall effect for juvenile boot camps was slightly lower than for adult boot camps. Moderator analysis showed that studies evaluating boot-camp programs with a strong treatment focus had a larger mean odds-ratio than studies evaluating boot camps with a weak treatment focus. 

**Conclusions:**
Although the overall effect appears to be that of &ldquo;no difference,&rdquo; some studies found that boot camp participants did better than the comparison, while others found that comparison samples did better. However, all of these studies had the common element of a militaristic boot camp program for offenders. The current evidence suggests that this common and defining feature of a boot-camp is not effective in reducing post boot-camp offending.
AU  - Wilson,
AU  - D.
AU  - MacKenzie,
AU  - D.
AU  - Mitchell,
AU  - F.
AU  - N.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.4073/csr.2005.6
KW  - Adolescents
KW  - Adults
KW  - Offenders
KW  - Crime
KW  - Penal sanctions
PY  - 2005
T2  - Campbell Systematic Reviews
TI  - Effects of Correctional Boot Camps on Offending: A Systematic Review
ER  -
TY  - JOUR
AB  - Current recommendations for the treatment of attention deficit/hyperactivity disorder (ADHD) call For a multimodal approach including a combination of medication, behavior modification, school accommodations, and ancillary services. 

One method that has been proposed as an effective and efficient means for increasing students&#039; attention and academic productivity is self-regulation. 

This article reports the results of a meta-analysis of the literature on the use of four self-regulation interventions (self-monitoring, self-monitoring plus reinforcement, self management, and self-reinforcement) for children with ADHD. 

Combined effect sizes for these four treatments were greater than 1.0 for on-task behavior, inappropriate behavior, and academic accuracy and productivity, indicating that self-regulation interventions are effective for children with ADHD.
AD  - Univ Nebraska, Lincoln, NE 68583 USA. Univ Iowa, Iowa City, IA 52242 USA. Reid, R (reprint author), Univ Nebraska, 202L Barkley, Lincoln, NE 68583 USA.
AN  - WOS:000229959900003
AU  - Reid,
AU  - R.
AU  - Trout,
AU  - A.
AU  - L.
AU  - Schartz,
AU  - M.
DA  - Sum
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /CRDWeb/ShowRecord.asp
J2  - Except. Child.
KW  - DEFICIT HYPERACTIVITY DISORDER LEARNING-DISABLED CHILDREN CLASSROOM-BEHAVIOR ACADEMIC-PERFORMANCE TASK BEHAVIOR MANAGEMENT ADOLESCENTS ADHD REINFORCEMENT METAANALYSIS Education, Special Rehabilitation
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 937XN Times Cited: 65 Cited Reference Count: 61 Reid, R Trout, AL Schartz, M 65 COUNCIL EXCEPTIONAL CHILDREN ARLINGTON EXCEPT CHILDREN
PY  - 2005
SP  - 361-377
T2  - Exceptional Children
TI  - Self-regulation interventions for children with attention deficit/hyperactivity disorder
UR  - &lt;Go to ISI&gt;://WOS:000229959900003
VL  - 71
ER  -
TY  - JOUR
AB  - This research synthesis examines rigorous evaluations of interventions for children diagnosed with ODD. The primary goal was to identify and synthesize through meta-analysis what is known regarding the effectiveness of various treatments. A secondary goal was to assess the degree to which treatment effectiveness is being evaluated in multiple domains. Seven studies were identified that measured outcomes in six domains. As in prior reviews, interventions demonstrate improvements in the child&#039;s behavior at home and parental stress/strain. Support for improvements in behavior and performance in school is not as strong due in part to a scarcity of attention to the multiple domains of functioning. The interventions reviewed here demonstrate some benefit and no harm; however, there is room to strengthen the research base. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - C Bradley, M. C.: marycary@sp2.upenn.edu Bradley, M. C.: Graduate School of Education, University of Pennsylvania, 3700 Walnut Street, Room 409, Philadelphia, PA, US, 19104, marycary@sp2.upenn.edu Bradley, M. C.: Graduate School of Education, University of Pennsylvania, Philadelphia, PA, US Mandell, David: Graduate School of Education, University of Pennsylvania, Philadelphia, PA, US
AN  - 2006-01989-005
AU  - Bradley,
AU  - M.
AU  - C.
AU  - Mandell,
AU  - D.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s11292-005-0062-3
DP  - Ovid Technologies
KW  - oppositional defiant disorder, intervention effectiveness *Conduct Disorder *Intervention *Oppositional Defiant Disorder *Treatment Effectiveness Evaluation Health &amp; Mental Health Treatment &amp; Prevention [3300] Behavior Disorders &amp; Antisocial Behavior [3
LA  - English
M3  - Meta Analysis
PY  - 2005
SP  - 343-365
T2  - Journal of Experimental Criminology
TI  - Oppositional defiant disorder: A systematic review of evidence of intervention effectiveness
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2006-01989-005
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs11292-005-0062-3&amp;issn=1573-3750&amp;isbn=&amp;volume=1&amp;issue=3&amp;spage=343&amp;pages=343-365&amp;date=2005&amp;title=Journal+of+Experimental+Criminology&amp;atitle=Oppositional+defiant+disorder%3A+A+systematic+review+of+evidence+of+intervention+effectiveness.&amp;aulast=Bradley&amp;pid=%3Cauthor%3EBradley%2C+M.+C%3C%2Fauthor%3E%3CAN%3E2006-01989-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs11292-005-0062-3http://download.springer.com/static/pdf/551/art%253A10.1007%252Fs11292-005-0062-3.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs11292-005-0062-3&amp;token2=exp=1435232683~acl=%2Fstatic%2Fpdf%2F551%2Fart%25253A10.1007%25252Fs11292-005-0062-3.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs11292-005-0062-3*~hmac=4c85fc4a6d73d4f119e84bbacdf86ec7033c659791f74ecf7aab224da01a172a
VL  - 1
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To examine the evidence for the effectiveness of clinical interventions designed to reduce the repetition of deliberate self-harm (DSH) in adolescents and young adults. 

**METHODS: **
Electronic databases were searched for papers describing randomised and clinical control trials (RCTs) and quasi-experimental studies of interventions targeting adolescents and young adults presenting to clinical services following DSH or suicidal ideation. 

**RESULTS: **
Three RCTs, four clinical control trials and three quasi-experimental studies were identified. Group therapy, trialled in a RCT, was the only specific programme which led to a significant reduction in rates of repetition of self-harm. Attendance at follow-up did not improve significantly regardless of the intervention, while one clinically controlled trial of intensive intervention resulted in poorer attendance at follow-up. One quasi-experimental study of family therapy resulted in a significant reduction in suicidal ideation. 

**CONCLUSIONS: **
The evidence base for treatments designed to reduce the repetition of self-harm in adolescents and young adults is very limited. Expensive interventions such as intensive aftercare offer no clear benefit over routine aftercare. Given that deliberate self-harm among young people is a common clinical problem further good quality treatment studies are warranted. Careful consideration should be given to process evaluation to determine which individual components of any given intervention are effective.
AD  - Burns,Jane. &#039;beyondblue; the national depression initiative&#039; Hawthorn West, Victoria, Australia. jane.burns@beyondblue.org.au
AN  - 15701059
AU  - Burns,
AU  - J.
AU  - Dudley,
AU  - M.
AU  - Hazell,
AU  - P.
AU  - Patton,
AU  - G.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/j.1440-1614.2005.01532.x
DP  - Ovid Technologies
J2  - Aust N Z J Psychiatry
KW  - Adolescent Adult *Evidence-Based Medicine Humans Outcome and Process Assessment (Health Care) Randomized Controlled Trials as Topic Secondary Prevention *Self-Injurious Behavior/pc [Prevention &amp; Control] Self-Injurious Behavior/px [Psychology] *Suicide
LA  - English
M3  - Comparative Study Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Burns, Jane Dudley, Michael Hazell, Philip Patton, George Comment in: Aust N Z J Psychiatry. 2005 Oct;39(10):948-9; PMID: 16168025
PY  - 2005
SP  - 121-8
T2  - Australian and New Zealand Journal of Psychiatry
TI  - Clinical management of deliberate self-harm in young people: the need for evidence-based approaches to reduce repetition
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=15701059 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15701059&amp;id=doi:&amp;issn=0004-8674&amp;isbn=&amp;volume=39&amp;issue=3&amp;spage=121&amp;pages=121-8&amp;date=2005&amp;title=Australian+%26+New+Zealand+Journal+of+Psychiatry&amp;atitle=Clinical+management+of+deliberate+self-harm+in+young+people%3A+the+need+for+evidence-based+approaches+to+reduce+repetition.&amp;aulast=Burns&amp;pid=%3Cauthor%3EBurns+J%3C%2Fauthor%3E%3CAN%3E15701059%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/doi/10.1111/j.1440-1614.2005.01532.x/abstracthttp://onlinelibrary.wiley.com/store/10.1111/j.1440-1614.2005.01532.x/asset/j.1440-1614.2005.01532.x.pdf?v=1&amp;t=ibc14l5z&amp;s=7a5d8f2d0e4cf4a9d5042ef428c27945a55cb0c2
UR  - http://journals.sagepub.com/doi/abs/10.1080/j.1440-1614.2005.01532.x?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%3dpubmed
VL  - 39
ER  -
TY  - JOUR
AB  - **Background:** 
Several systematic reviews of school-based smoking prevention trials have shown short-term decreases in smoking prevalence but have not examined long-term follow-up evaluation. The purpose of this study was to conduct a systematic review of rigorously evaluated interventions for school-based smoking prevention with long-term follow-up data. 

**Methods:** 
We searched online bibliographic databases and reference lists from review articles and selected studies. We included all school-based, randomized, controlled trials of smoking prevention with follow-up evaluation to age 18 or 12th grade and at least 1 year after intervention ended, and that had smoking prevalence as a primary outcome. The primary outcome was current smoking prevalence (defined as at least I cigarette in the past month). 

**Results:** 
The abstracts or full-text articles of 177 relevant studies were examined, of which 8 met the selection criteria. The 8 articles included studies differing in intervention intensity, presence of booster sessions, follow-up periods, and attrition rates. Only one study showed decreased smoking prevalence in the intervention group. 

**Conclusions: **
Few studies have evaluated the long-term impact of school-based smoking prevention programs rigorously. Among the 8 programs that have follow-up data to age 18 or 12th grade, we found little to no evidence of long-term effectiveness. 

2005 Society for Adolescent Medicine. All rights reserved.
AD  - Indiana Univ, Sch Med, Childrens Hlth Serv Res, Indianapolis, IN 46202 USA. Univ Washington, Dept Pediat, Seattle, WA 98195 USA. Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA. Univ Washington, Inst Child Hlth, Seattle, WA 98195 USA. Wiehe, SE (reprint author), Indiana Univ, Sch Med, Childrens Hlth Serv Res, 699 W Dr,RR 330, Indianapolis, IN 46202 USA. swiehe@iupui.edu
AN  - WOS:000227406900003
AU  - Wiehe,
AU  - S.
AU  - E.
AU  - Garrison,
AU  - M.
AU  - M.
AU  - Christakis,
AU  - D.
AU  - A.
AU  - Ebel,
AU  - B.
AU  - E.
AU  - Rivara,
AU  - F.
AU  - P.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.jadohealth.2004.12.003
J2  - J. Adolesc. Health
KW  - smoking prevention school youth ABUSE RESISTANCE EDUCATION MASS-MEDIA CAMPAIGNS NO TOBACCO USE DRUG-ABUSE CIGARETTE-SMOKING PROJECT DARE BEHAVIOR OUTCOMES RANDOMIZED TRIAL NATURAL-HISTORY META-ANALYSIS Psychology, Developmental Public, Environmental &amp; O
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 903DY Times Cited: 127 Cited Reference Count: 63 Wiehe, SE Garrison, MM Christakis, DA Ebel, BE Rivara, FP Ebel, Beth/F-4544-2014 129 ELSEVIER SCIENCE INC NEW YORK J ADOLESCENT HEALTH
PY  - 2005
SP  - 162-169
T2  - Journal of Adolescent Health
TI  - A systematic review of school-based smoking prevention trials with long-term follow-up
UR  - &lt;Go to ISI&gt;://WOS:000227406900003http://ac.els-cdn.com/S1054139X04004604/1-s2.0-S1054139X04004604-main.pdf?_tid=84972634-165a-11e5-b5f4-00000aacb360&amp;acdnat=1434701553_6f2321b6c0b38c03e62d84d675064035
VL  - 36
ER  -
TY  - JOUR
AB  - **Background **
Psychosocial and emotional factors are important in childhood asthma. Nevertheless, drug therapy alone continues to be the main treatment. Treatment programmes that include behavioural or psychological interventions have been developed to improve disturbed family relations in the families of children with severe asthma. These approaches have been extended to examine the efficacy of family therapy to treat childhood asthma in a wider group of patients. This review systematically examines these studies. 

**Objectives **
Recognition that asthma can be associated with emotional disturbances has led to the investigation of the role of family therapy in reducing the symptoms and impact of asthma in children. The objective of this review was to assess the effects of family therapy as an adjunct to medication for the treatment of asthma in children.

**Search Strategy **
We searched the Cochrane Airways Group trials register, Psychlit and Psychinfo. Searches are current as of January 2005. Selection criteria Randomised trials comparing children undergoing systematic therapy focusing on the family in conjunction with asthma medication, with children taking asthma medication only. 

**Data collection and analysis **
Two reviewers assessed the studies for inclusion in the review. 

**Main results **
Two trials with a total of 55 children were included. It was not possible to combine the findings of these two studies because of differences in outcome measures used. In one study, gas volume, peak expiratory flow rate and daytime wheeze showed improvement in family therapy patients compared to controls. In the other study, there was an improvement in overall clinical assessment and number of functionally impaired days in the patients receiving family therapy. There was no difference in forced expiratory volume or medication use in both studies. 

**Authors&#039; conclusions **
There is some indication that family therapy may be a useful adjunct to medication for children with asthma. This conclusion is limited by small study sizes and lack of standardisation in the choice of outcome measures.
AD  - Royal Brompton Hosp, London SW3 6LY, England. Yorke, J (reprint author), Royal Brompton Hosp, Sydney St, London SW3 6LY, England. J.Yorke@rbh.nthames.nhs.uk
AN  - WOS:000232199200112
AU  - Yorke,
AU  - J.
AU  - Shuldham,
AU  - C.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD000089.pub2
J2  - Cochrane Database Syst Rev.
KW  - INTRACTABLE ASTHMA CHILDHOOD ASTHMA CONTROLLED TRIAL INTERVENTION MANAGEMENT COMPONENTS SPECTRUM Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 968YJ Times Cited: 0 Cited Reference Count: 32 Yorke, J Shuldham, C Yorke, Janelle/A-5393-2015 Yorke, Janelle/0000-0002-1344-5944 WILEY-LISS HOBOKEN COCHRANE DB SYST REV
PY  - 2005
SP  - 18
T2  - Cochrane Database of Systematic Reviews
TI  - Family therapy for chronic asthma in children
UR  - &lt;Go to ISI&gt;://WOS:000232199200112http://onlinelibrary.wiley.com/store/10.1002/14651858.CD000089.pub2/asset/CD000089.pdf?v=1&amp;t=ib7uzom5&amp;s=aabe29e3309ea97d8894216b7e5a4a0cf150c4d9
ER  -
TY  - JOUR
AB  - **Objective: **
This article is a systematic review identifying effective family-based interventions for adolescent substance use problems. 

**Method: **
A substantive review of each intervention is conducted using guidelines for effective treatment for substance use problems. Additionally, a methodological review of each study is done using criteria for empirically validated treatments. 

**Results: **
Treatment components of five interventions-Brief Strategic Family The rap); (BSFT), Family Behavior Therapy, Functional Family Therapy, Multidimensional Family Therapy (MDFT), and Multisystemic Treatment-were consistent with a majority of guidelines for effective treatment. Notable exceptions include no aftercare and poor treatment retention. MDFT and BSFT met criteria of probably efficacious treatment, whereas the other interventions represented promising treatments. Moreover MDFT demonstrated clinically significant changes in substance use and large effect sizes at posttreatment and follow-up. 

**Conclusion: **
To increase provision of effective adolescent substance abuse treatment, social workers should use these research findings to guide implementation.
AD  - Florida Int Univ, Sch Social Work, Community Based Intervent Res Grp, Miami, FL 33199 USA. Austin, AM (reprint author), Florida Int Univ, Sch Social Work, Community Based Intervent Res Grp, 11200 SW 8th St,MARC 310, Miami, FL 33199 USA. aaus003@fiu.edu
AN  - WOS:000226786200001
AU  - Austin,
AU  - A.
AU  - M.
AU  - Macgowan,
AU  - M.
AU  - J.
AU  - Wagner,
AU  - E.
AU  - F.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1049731504271606
J2  - Res. Soc. Work. Pract.
KW  - adolescent substance use family-based treatment efficacy DRUG-ABUSE TREATMENT ONE-PERSON THERAPY RELAPSE YOUTH PREVENTION DISORDERS CONJOINT EFFICACY OUTCOMES Social Work
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 894JB Times Cited: 35 Cited Reference Count: 43 Austin, AM Macgowan, MJ Wagner, EF 35 SAGE PUBLICATIONS INC THOUSAND OAKS RES SOCIAL WORK PRAC
PY  - 2005
SP  - 67-83
T2  - Research on Social Work Practice
TI  - Effective family-based interventions for adolescents with substance use problems: A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000226786200001http://rsw.sagepub.com/content/15/2/67http://rsw.sagepub.com/content/15/2/67.full.pdf
VL  - 15
ER  -
TY  - JOUR
AB  - Are preventive early childhood interventions effective in improving home environments, as assessed with the HOME inventory (Caldwell &amp; Bradley, 1984)? The authors traced 48 published articles, presenting 56 intervention effects (N = 7,350). The combined effect size on the HOME total score was d = 0.20 (p &lt; .001). Randomized intervention studies were effective, but the combined effect size was limited (d = 0.13). Nonrandomized studies showed inflated effects (d = 0.58). Interventions with middle-class, non-adolescent parents showed higher effect sizes than interventions with low-SES or adolescent samples. Effective interventions used a moderate number of sessions in a limited period and were home-based. Learning Materials, Involvement, and Responsivity showed significant intervention effects. Families in better living conditions profited more from parent education (the Matthew effect). (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Bakermans-Kranenburg, Marian J.: bakermans@fsw.leidenuniv.nl; van IJzendoorn, Marinus H.: vanijzen@fsw.leidenuniv.nl; Bradley, Robert H.: rhbradley@ualr.edu Bakermans-Kranenburg, Marian J.: Centre for Child and Family Studies, Department of Education and Child Studies, Leiden University, P.O. Box 9555, Leiden, Netherlands, 2300 RB, bakermans@fsw.leidenuniv.nl Bakermans-Kranenburg, Marian J.: Centre for Child and Family Studies, Department of Education and Child Studies, Leiden University, Leiden, Netherlands van IJzendoorn, Marinus H.: Department of Education and Child Studies, Leiden University, Leiden, Netherlands Bradley, Robert H.: Center for Applied Studies in Education, University of Arkansas, Little Rock, AR, US
AN  - 2005-05209-001
AU  - Bakermans-Kranenburg,
AU  - M.
AU  - J.
AU  - van
AU  - Ijzendoorn,
AU  - M.
AU  - H.
AU  - Bradley,
AU  - R.
AU  - H.
DA  - Spr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3102/00346543075001001
DP  - Ovid Technologies
KW  - Matthew effect, early childhood intervention, home environment, socioeconomic status *Early Intervention *Home Environment *Socioeconomic Status Community &amp; Social Services [3373] Human
LA  - English
M3  - Meta Analysis
PY  - 2005
SP  - 1-26
T2  - Review of Educational Research
TI  - Those Who Have, Receive: The Matthew Effect in Early Childhood Intervention in the Home Environment
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2005-05209-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.3102%2F00346543075001001&amp;issn=0034-6543&amp;isbn=&amp;volume=75&amp;issue=1&amp;spage=1&amp;pages=1-26&amp;date=2005&amp;title=Review+of+Educational+Research&amp;atitle=Those+Who+Have%2C+Receive%3A+The+Matthew+Effect+in+Early+Childhood+Intervention+in+the+Home+Environment.&amp;aulast=Bakermans-Kranenburg&amp;pid=%3Cauthor%3EBakermans-Kranenburg%2C+Marian+J%3C%2Fauthor%3E%3CAN%3E2005-05209-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rer.sagepub.com/content/75/1/1http://rer.sagepub.com/content/75/1/1.full.pdf
VL  - 75
ER  -
TY  - JOUR
AB  - OBJECTIVES:
This review identified reports of acupuncture for childhood nocturnal enuresis, with the aim of ascertaining whether acupuncture is efficacious and or better than standard therapy for treating enuresis. 

MATERIALS AND METHODS: 
Studies of children of either gender &lt;18 years of age who received acupuncture treatment for nocturnal enuresis, were considered. The primary outcome measure was change in the mean number of wet episodes following treatment. Electronic searching was supplemented by hand searching of western medicine and traditional Chinese medicine (TCM) journals along with English language alternative medicine journals. Trials were assessed for quality and sources of bias. Meta-analysis was performed and the overall weighted odds ratio (OR) and associated 95% confidence interval (CI) were computed using the fixed effect model; the Forest plot was used to demonstrate results. 

RESULTS: 
Two hundred six abstracts were identified, of which 11 studies were eligible for data extraction. All the trials were of low methodological quality. There was some evidence that acupuncture is useful for nocturnal enuresis when used in conjunction with other treatment that may also include a different form of acupuncture (OR 3.98, CI: 2.2-7.2). When one form of acupuncture is compared with another there was marked heterogeneity, implying that some forms of acupuncture are effective. 

CONCLUSION: This review provides tentative evidence for the efficacy of acupuncture for the treatment of childhood nocturnal enuresis. Due to the low methodological quality of studies, evidence to identify, which parameters of acupuncture work best, is lacking. More rigorous trials are clearly warranted.
AD  - Bower,Wendy F. Department of Surgery, Division of Paediatric Surgery and Paediatric Urology, The Chinese University of Hong Kong, Hong Kong. wendyb@surgery.cuhk.edu.hk
AN  - 15791606
AU  - Bower,
AU  - W.
AU  - F.
AU  - Diao,
AU  - M.
AU  - Tang,
AU  - J.
AU  - L.
AU  - Yeung,
AU  - C.
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/nau.20108
DP  - Ovid Technologies
J2  - Neurourol Urodyn
KW  - *Acupuncture Therapy Adolescent Child *Enuresis/th [Therapy] Humans *Medicine, Chinese Traditional
L1  - internal-pdf://1687758845/Bower-2005-Acupuncture for nocturnal enuresis.pdf
internal-pdf://0921041730/Bower-2005-Acupuncture for nocturnal enuresis1.pdf
LA  - English
M3  - Review
N1  - Bower, Wendy F Diao, M Tang, J L Yeung, C K
PY  - 2005
SP  - 267-72
T2  - Neurourology and Urodynamics
TI  - Acupuncture for nocturnal enuresis in children: a systematic review and exploration of rationale
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=15791606
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15791606&amp;id=doi:&amp;issn=0733-2467&amp;isbn=&amp;volume=24&amp;issue=3&amp;spage=267&amp;pages=267-72&amp;date=2005&amp;title=Neurourology+%26+Urodynamics&amp;atitle=Acupuncture+for+nocturnal+enuresis+in+children%3A+a+systematic+review+and+exploration+of+rationale.&amp;aulast=Bower&amp;pid=%3Cauthor%3EBower+WF%3C%2Fauthor%3E%3CAN%3E15791606%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - http://onlinelibrary.wiley.com/store/10.1002/nau.20108/asset/20108_ftp.pdf?v=1&amp;t=ib99l23d&amp;s=bf5220593461fb355a8c7680570abf5f08b42386
UR  - http://onlinelibrary.wiley.com/store/10.1002/nau.20108/asset/20108_ftp.pdf?v=1&amp;t=j125veox&amp;s=3a8fb4baa6f9765c07f28d20953c3f13a73ca04d
VL  - 24
ER  -
TY  - JOUR
AB  - -
AD  - CDCP, Community Guide Branch, Epidemiol Program Off, Atlanta, GA 30333 USA. CDCP, Natl Ctr Injury Prevention, Atlanta, GA 30333 USA. Columbia Univ, Dept Psychiat &amp; Publ Hlth, New York, NY USA. Natl Inst Justice, Washington, DC USA. NIMH, Bethesda, MD 20892 USA. Hahn, RA (reprint author), CDCP, Community Guide Branch, Epidemiol Program Off, 1600 Clifton Rd,MS E-90, Atlanta, GA 30333 USA. RHahn@cdc.gov
AN  - WOS:000227057600004
AU  - Bilukha,
AU  - O.
AU  - Hahn,
AU  - R.
AU  - A.
AU  - Crosby,
AU  - A.
AU  - Fullilove,
AU  - M.
AU  - T.
AU  - Liberman,
AU  - A.
AU  - Moscicki,
AU  - E.
AU  - Snyder,
AU  - S.
AU  - Tuma,
AU  - F.
AU  - Corso,
AU  - P.
AU  - Schofield,
AU  - A.
AU  - Briss,
AU  - P.
AU  - A.
AU  - Preventive
AU  - Task
AU  - Force,
AU  - on
AU  - Community,
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/j.amepre.2004.10.004
J2  - Am. J. Prev. Med.
KW  - RANDOMIZED CONTROLLED-TRIAL HEALTHY START PROGRAM BIRTH-WEIGHT INFANTS 15-YEAR FOLLOW-UP ABUSE PREVENTION ANTISOCIAL-BEHAVIOR AT-RISK SERVICES OUTCOMES NEGLECT Public, Environmental &amp; Occupational Health Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 898DY Times Cited: 56 Cited Reference Count: 75 Bilukha, O Hahn, RA Crosby, A Fullilove, MT Liberman, A Moscicki, E Snyder, S Tuma, F Corso, P Schofield, A Briss, PA 58 ELSEVIER SCIENCE INC NEW YORK AM J PREV MED 1
PY  - 2005
SP  - 11-39
T2  - American Journal of Preventive Medicine
TI  - The effectiveness of early childhood home visitation in preventing violence - A systematic review
UR  - &lt;Go to ISI&gt;://WOS:000227057600004http://ac.els-cdn.com/S0749379704002831/1-s2.0-S0749379704002831-main.pdf?_tid=a31b7550-167e-11e5-ae1c-00000aab0f6c&amp;acdnat=1434717066_35d30876825b6bfc1ef1f213b382e065
VL  - 28
ER  -
TY  - JOUR
AB  - **Background:** 
Attention-deficit hyperactivity disorder (ADHD) is diagnosed in between 3% and 7% of school-age children and consists of the core symptoms of inattention, impulsivity and hyperactivity. Children are often treated with medication, usually stimulant medication such as methylphenidate. Stimulant medication has been found to be effective for alleviating ADHD symptoms, at least in the short term. ADHD is also treated with a variety of psychosocial and psychoeducational interventions for parents, children, and with multicomponent interventions combined with medication management. However, many patients (10 to 13% of patients) cannot or prefer not to take medication. Family therapy without medication may help to develop structure in the family, help to manage children&#039;s behaviour, and may help families cope with distress from the presence of the disorder.

**Objectives:** 
This review seeks to address the question of whether family therapy without medication can reduce the core symptoms of ADHD as compared to no treatment or standard treatment.

**Search methods:** 
The following electronic databases were searched using a specific search strategy: The Cochrane Central Register of Controlled Trials (The Cochrane Library Issue 3, 2004), MEDLINE (1966 to April 2004), PsycINFO (1872 to April 2004), CINAHL (1982 to April 2004), Biosis (Biological Abstracts) (1985 to March 2004), Dissertation Abstracts (1980 to April 2004), and Sociological Abstracts (Sociofile) (1963 to April 2004). Hand searches of relevant journals and bibliographies were also conducted and experts in the field were contacted for further information.Selection criteria: Included studies were randomised controlled trials investigating the efficacy of behavioural family therapy, cognitive behavioural family therapy, or functional family therapy for children with ADHD or ADD (Attention Deficit Disorder).

**Data collection and analysis:** 
Studies were evaluated for methodological quality and to determine whether they met the inclusion criteria.

**Main results**
This assessment yielded two studies. Data were extracted for both studies. The findings from Jensen 1999 (N=579) indicate that no difference can be detected between the efficacy of behavioural family therapy and treatment as usual in the community. The finding from the available data from Horn 1991 slightly favours treatment over medication placebo.

**Authors&#039; conclusions:** 
Further research examining the effectiveness of family therapy versus a no-treatment control condition is needed to determine whether family therapy is an effective intervention for children with ADHD. There were no results available from studies investigating forms of family therapy other than behavioural family therapy.
AN  - CD005042
AU  - Bjornstad,
AU  - G.
AU  - J.
AU  - Montgomery,
AU  - P.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd005042
KW  - Attention Deficit Disorder with Hyperactivity [drug therapy] [therapy]
KW  - Family Therapy [methods]
KW  - Randomized Controlled Trials as Topic
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2005
T2  - Cochrane Database of Systematic Reviews
TI  - Family therapy for attention-deficit disorder or attention-deficit/hyperactivity disorder in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005042.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD005042.pub2/asset/CD005042.pdf?v=1&amp;t=iw7jgogy&amp;s=edf631e4192d36f9dd1ec876a51bfc28d13b0f6e
ER  -
TY  - JOUR
AB  - **Background **
Laws restricting sales of tobacco products to minors exist in many countries, but young people may still purchase cigarettes easily. 

**Objectives **
The review assesses the effects of interventions to reduce underage access to tobacco by deterring shopkeepers from making illegal sales. 

**Search strategy **
We searched the Cochrane Tobacco Addiction group trials register, MEDLINE and EMBASE. Date of the most recent searches: September 2004. Selection criteria We included controlled trials and uncontrolled studies with pre- and post intervention assessment of interventions to change retailers&#039; behaviour. The outcomes were changes in retailer compliance with legislation (assessed by test purchasing), changes in young people&#039;s smoking behaviour, and perceived ease of access to tobacco products. 

**Data collection and analysis** 
One reviewer prescreened studies for relevance, and both reviewers independently assessed the studies for inclusion. One reviewer extracted data from included studies and the second checked them. Study designs and types of intervention were heterogeneous so results were synthesized narratively, with greater weight given to controlled studies. 
**Main results **
We identified 34 studies of which 14 had data from a control group for at least one outcome. Giving retailers information was less effective in reducing illegal sales than active enforcement or multicomponent educational strategies, or both. No strategy achieved complete, sustained compliance. In three controlled trials, there was little effect of intervention on youth perceptions of access or prevalence of smoking. 

**Authors&#039; conclusions **
Interventions with retailers can lead to large decreases in the number of outlets selling tobacco to youths. However, few of the communities studied in this review achieved sustained levels of high compliance. This may explain why there is limited evidence for an effect of intervention on youth perception of ease of access to tobacco, and on smoking behaviour.
AD  - Univ Oxford, Dept Primary Hlth Care, Oxford OX3 7LF, England. Stead, LF (reprint author), Univ Oxford, Dept Primary Hlth Care, Old Rd Campus, Oxford OX3 7LF, England. lindsay.stead@dphpc.ox.ac.uk
AN  - WOS:000232097000094
AU  - Stead,
AU  - L.
AU  - F.
AU  - Lancaster,
AU  - T.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1002/14651858.CD001497
J2  - Cochrane Database Syst Rev.
KW  - ABANDON YOUTH ACCESS REDUCE CIGARETTE SALES HIGH-SCHOOL-STUDENTS ILLEGAL TOBACCO ADOLESCENTS ACQUISITION NONCOMMERCIAL SOURCES SIMULATION-MODEL UNDERAGE YOUTH 3 COMMUNITIES YOUNG-PEOPLE Medicine, General &amp; Internal
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 967ND Times Cited: 0 Cited Reference Count: 112 Stead, LF Lancaster, T WILEY-LISS HOBOKEN COCHRANE DB SYST REV
PY  - 2005
SP  - 44
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for preventing tobacco sales to minors
UR  - &lt;Go to ISI&gt;://WOS:000232097000094http://onlinelibrary.wiley.com/store/10.1002/14651858.CD001497.pub2/asset/CD001497.pdf?v=1&amp;t=ib7ur0ay&amp;s=c43ec15d8dea08bc4c27a5c7e6a0201683a5abfe
ER  -
TY  - JOUR
AB  - The purpose of this review was to report on the effectiveness and focus of academic self-management interventions for children and adolescents with emotional and behavioral disorders. Twenty-two studies published in 20 articles and involving 78 participants met inclusionary criteria. The overall mean effect size (ES) across those studies was 1.80 (range -0.46 to 3.00), indicating effects were generally large in magnitude and educationally meaningful. Self-monitoring interventions were the predominant type of self-management technique used by researchers. The mean ES for intervention types were self-evaluation (1.13), self-monitoring (1.90), strategy instruction techniques (1.75), self-instruction techniques (2.71), and multiple-component interventions (2.11). Interventions targeted improvement in math calculation skills more than any other area. The mean ES by academic area were math interventions (1.97), writing (1.13), reading (2.28), and social studies (2.66). There was evidence to support a claim of the generalization and maintenance of findings. Implications, limitations, and areas for future research are discussed. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Ryan, Joseph B.: Joe_ryan1@hotmail.com Ryan, Joseph B.: Clemson University, 407 Tillman Hall, Clemson, SC, US, 29634, Joe_ryan1@hotmail.com Mooney, Paul: Louisiana State University, LA, US Ryan, Joseph B.: Clemson University, Clemson, SC, US Uhing, Brad M.: Wichita State University, Wichita, KS, US Reid, Robert: Wichita State University, Wichita, KS, US Epstein, Michael H.: Wichita State University, Wichita, KS, US
AN  - 2005-08089-004
AU  - Mooney,
AU  - P.
AU  - Ryan,
AU  - J.
AU  - B.
AU  - Uhing,
AU  - B.
AU  - M.
AU  - Reid,
AU  - R.
AU  - Epstein,
AU  - M.
AU  - H.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1007/s10864-005-6298-1
DP  - Ovid Technologies
KW  - self management interventions, academic outcomes, emotional disorders, behavioral disorders, children, adolescents, students *Academic Achievement *Disorders *School Based Intervention *Self Management *Self Monitoring Behavior Disorders Emotional Distu
LA  - English
M3  - Literature Review
PY  - 2005
SP  - 203-221
T2  - Journal of Behavioral Education
TI  - A Review of Self-Management Interventions Targeting Academic Outcomes for Students with Emotional and Behavioral Disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2005-08089-004
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1007%2Fs10864-005-6298-1&amp;issn=1053-0819&amp;isbn=&amp;volume=14&amp;issue=3&amp;spage=203&amp;pages=203-221&amp;date=2005&amp;title=Journal+of+Behavioral+Education&amp;atitle=A+Review+of+Self-Management+Interventions+Targeting+Academic+Outcomes+for+Students+with+Emotional+and+Behavioral+Disorders.&amp;aulast=Mooney&amp;pid=%3Cauthor%3EMooney%2C+Paul%3C%2Fauthor%3E%3CAN%3E2005-08089-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://link.springer.com/article/10.1007%2Fs10864-005-6298-1http://download.springer.com/static/pdf/279/art%253A10.1007%252Fs10864-005-6298-1.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10864-005-6298-1&amp;token2=exp=1435232116~acl=%2Fstatic%2Fpdf%2F279%2Fart%25253A10.1007%25252Fs10864-005-6298-1.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Farticle%252F10.1007%252Fs10864-005-6298-1*~hmac=9b9b59d2c0018852aa4a6fd25e8fa13fed569d3f7c732764b29d9041650df32d
VL  - 14
ER  -
TY  - JOUR
AB  - **OBJECTIVES:** 
To establish the clinical effectiveness and cost-effectiveness of electroconvulsive therapy (ECT) for depressive illness, schizophrenia, catatonia and mania.

**DATA SOURCES:** 
Electronic bibliographic databases. The reference lists of relevant articles and health services research-related resources were consulted via the Internet.

**REVIEW METHODS:** 
Identified studies were examined to ascertain whether they met the inclusion criteria for the review. The study quality of relevant articles was assessed using standard checklists and data were abstracted using standardised forms into a database. Where relevant, results from studies were pooled for meta-analysis. Two economic models were developed primarily based on evidence from the clinical effectiveness analysis and limited quality of life studies.

**RESULTS:**
Two good-quality systematic reviews of randomised evidence of the efficacy and safety of ECT in people with depression, schizophrenia, catatonia and mania were identified. Four systematic reviews on non-randomised evidence were also identified, although only one of these could be described as good quality. There was no randomised evidence of the effectiveness of ECT in specific subgroups including older people, children and adolescents, people with catatonia and women with postpartum exacerbations of depression or schizophrenia. The economic modelling results for depression did not demonstrate that any of the scenarios had a clear economic benefit over the others, mainly because of the uncertainty surrounding the clinical effectiveness of the different treatments and the quality of life utility gains. Sensitivity analysis surrounding the cost of ECT and the quality of life utility values had little effect on the overall results. The results of the model for schizophrenia adapted to include ECT suggest that clozapine is a cost-effective treatment compared with ECT. For patients who fail to respond to clozapine, ECT treatment may be preferred to the comparative treatment of haloperidol/chlorpromazine.

**CONCLUSIONS:** 
Real ECT is probably more effective than sham ECT, but as stimulus parameters have an important influence on efficacy, low-dose unilateral ECT is no more effective than sham ECT. ECT is probably more effective than pharmacotherapy in the short term and limited evidence suggests that ECT is more effective than repetitive transcranial magnetic stimulation. Tricyclic antidepressants (TCAs) may improve the antidepressant effect of ECT during the course of treatment. Continuation pharmacotherapy with TCAs combined with lithium in people who have responded to ECT reduces the rate of relapses. Overall, gains in the efficacy of the intervention depending on the stimulus parameters of ECT are achieved only at the expense of an increased risk of cognitive side-effects. Limited evidence suggests these effects do not last beyond 6 months, but there is no evidence examining the longer term cognitive effects of ECT. There is little evidence of the long-term efficacy of ECT. ECT either combined with antipsychotic medication or as a monotherapy is not more effective than antipsychotic medication in people with schizophrenia. More research is needed to examine the long-term efficacy of ECT and the effectiveness of post-ECT pharmacotherapy, the short-term and longer term cognitive side-effects of ECT, and the impact of ECT on suicide and all-cause mortality. Further work is needed to examine the information needs of people deciding whether to accept ECT and how their decision-making can be facilitated. More research is also needed on the mechanism of action of ECT. Finally, the quality of reporting of trials in this area would be vastly improved by strict adherence to the Consolidated Standards of Reporting Trials recommendations. Economic analysis may identify areas in which research would be best targeted by identifying parameters where reducing the level of uncertainty would have the most effect in helping to make the decision on whether ECT is a cost-effective treatment. [References: 276]
AD  - Greenhalgh, J. Nuffield Institute for Health, University of Leeds, UK.
AN  - 15774232
AU  - Greenhalgh,
AU  - J.
AU  - Knight,
AU  - C.
AU  - Hind,
AU  - D.
AU  - Beverley,
AU  - C.
AU  - Walters,
AU  - S.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.3310/hta9090
DP  - Ovid Technologies
J2  - Health Technol Assess
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Antidepressive Agents, Tricyclic/tu [Therapeutic Use]
KW  - Bipolar Disorder/dt [Drug Therapy]
KW  - *Bipolar Disorder/th [Therapy]
KW  - Catatonia/dt [Drug Therapy]
KW  - *Catatonia/th [Therapy]
KW  - Combined Modality Therapy
KW  - *Cost-Benefit Analysis
KW  - Depression/dt [Drug Therapy]
KW  - *Depression/th [Therapy]
KW  - *Electroconvulsive Therapy/ec [Economics]
KW  - Electroconvulsive Therapy/sn [Statistics &amp; Numerical Data]
KW  - Evidence-Based Medicine
KW  - Female
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - *Models, Economic
KW  - Randomized Controlled Trials as Topic
KW  - Schizophrenia/dt [Drug Therapy]
KW  - *Schizophrenia/th [Therapy]
KW  - United Kingdom
KW  - 0 (Antidepressive Agents, Tricyclic)
L1  - internal-pdf://1259743308/Greenhalgh-2005.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
Review
N1  - Greenhalgh, JKnight, CHind, DBeverley, CWalters, S
PY  - 2005
SP  - 1-156, iii-iv
T2  - Health Technology Assessment (Winchester, England)
TI  - Clinical and cost-effectiveness of electroconvulsive therapy for depressive illness, schizophrenia, catatonia and mania: systematic reviews and economic modelling studies
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=15774232
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15774232&amp;id=doi:10.3310%2Fhta9090&amp;issn=1366-5278&amp;isbn=&amp;volume=9&amp;issue=9&amp;spage=1&amp;pages=1-156%2C+iii-iv&amp;date=2005&amp;title=Health+Technology+Assessment+%28Winchester%2C+England%29&amp;atitle=Clinical+and+cost-effectiveness+of+electroconvulsive+therapy+for+depressive+illness%2C+schizophrenia%2C+catatonia+and+mania%3A+systematic+reviews+and+economic+modelling+studies.&amp;aulast=Greenhalgh&amp;pid=%3Cauthor%3EGreenhalgh+J%3C%2Fauthor%3E%3CAN%3E15774232%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 9
ER  -
TY  - JOUR
AB  - This systematic review and meta-analysis aimed to evaluate the effect of modifying 18-carbon PUFA [18-C PUFA: alpha-linolenic acid (ALA, 18:3n-3) and linoleic acid (LA, 18:2n-6)] in the diets of term and preterm infants on DHA (22:6n-3) status, growth, and developmental outcomes. 

Only randomized controlled trials (RCT) involving formula-fed term and preterm infants, in which the 18-C PUFA composition of the formula was changed and growth or developmental outcomes were measured, were included. Differences were presented as control (standard formula) and treatment (18-C PUFA-supplemented formula). 

Primary analyses for term infants were 4 and 12 mon and for preterm infants 37-42 and 57 wk postmenstrual age. Five RCT involving term infants and three RCT involving preterm infants were included in the systematic review. Infants fed ALA-supplemented formula had significantly higher plasma and erythrocyte phospholipid DHA levels than control infants. There was no effect of ALA supplementation on the growth of preterm infants. 

In term infants, ALA supplementation was associated with increased weight and length at 12 mon, which was at least 4 mon after the end of dietary intervention. Developmental indices of term infants did not differ between groups. There was a transient improvement in the retinal function of preterm infants fed ALA-supplemented diets compared with controls. 

The findings suggest that ALA-supplemented diets improve the DHA status of infants. Further studies are needed to provide convincing evidence regarding the effects of ALA supplementation of formula on infant growth and development.
AD  - Udell, Tuesday. Department of Paediatrics &amp; Child Health, Flinders University, Bedford Park, South Australia, Australia.
AN  - 15825825
AU  - Udell,
AU  - T.
AU  - Gibson,
AU  - R.
AU  - A.
AU  - Makrides,
AU  - M.
AU  - Pufa
AU  - Study
AU  - Group
DA  - Jan
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
J2  - Lipids
KW  - Body Size/de [Drug Effects]
KW  - *Child Development/de [Drug Effects]
KW  - Dietary Supplements
KW  - Erythrocytes/ch [Chemistry]
KW  - Humans
KW  - *Infant Formula/ch [Chemistry]
KW  - Infant, Newborn
KW  - *Linoleic Acid/pd [Pharmacology]
KW  - Phospholipids/an [Analysis]
KW  - Phospholipids/bl [Blood]
KW  - Premature Birth
KW  - Retina/de [Drug Effects]
KW  - Time Factors
KW  - *alpha-Linolenic Acid/pd [Pharmacology]
KW  - 0 (Phospholipids)
KW  - 0RBV727H71 (alpha-Linolenic Acid)
KW  - 9KJL21T0QJ (Linoleic Acid)
L1  - internal-pdf://2844601004/Udell-2005-The effect of alpha-linolenic acid.pdf
LA  - English
M3  - Meta-Analysis
Research Support, Non-U.S. Gov&#039;t
Review
N1  - Udell, TuesdayGibson, Robert AMakrides, MariaPUFA Study Group
PY  - 2005
SP  - 1-11
T2  - Lipids
TI  - The effect of alpha-linolenic acid and linoleic acid on the growth and development of formula-fed infants: a systematic review and meta-analysis of randomized controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=15825825
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15825825&amp;id=doi:&amp;issn=0024-4201&amp;isbn=&amp;volume=40&amp;issue=1&amp;spage=1&amp;pages=1-11&amp;date=2005&amp;title=Lipids&amp;atitle=The+effect+of+alpha-linolenic+acid+and+linoleic+acid+on+the+growth+and+development+of+formula-fed+infants%3A+a+systematic+review+and+meta-analysis+of+randomized+controlled+trials.&amp;aulast=Udell&amp;pid=%3Cauthor%3EUdell+T%3C%2Fauthor%3E%3CAN%3E15825825%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://onlinelibrary.wiley.com/doi/abs/10.1007/s11745-005-1354-8
VL  - 40
ER  -
TY  - JOUR
AB  - Selective serotonin reuptake inhibitors (SSRIs) are frequently used to treat depression during pregnancy and the postpartum period. 

These drugs are capable of crossing the placenta and being transferred to the newborn during lactation. 

This report reviews the available information regarding the effects of SSRIs on the fetus and newborn; including long-term neurodevelopmental outcomes.
AD  - Lattimore,Keri A. Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Michigan, Ann Arbor, MI 48109-0254, USA.
AN  - 16015372
AU  - Lattimore,
AU  - K.
AU  - A.
AU  - Donn,
AU  - S.
AU  - M.
AU  - Kaciroti,
AU  - N.
AU  - Kemper,
AU  - A.
AU  - R.
AU  - Neal,
AU  - C.
AU  - R.
AU  - Vazquez,
AU  - D.
AU  - M.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1038/sj.jp.7211352
DP  - Ovid Technologies
J2  - J Perinatol
KW  - Child Development/de [Drug Effects] Female *Fetus/de [Drug Effects] Humans *Infant, Newborn/ph [Physiology] Maternal-Fetal Exchange Pregnancy *Serotonin Uptake Inhibitors/ae [Adverse Effects] 0 (Serotonin Uptake Inhibitors)
L1  - internal-pdf://3095275412/Lattimore-2005-Selective serotonin reuptake in.pdf
LA  - English
M3  - Meta-Analysis Research Support, N.I.H., Extramural Research Support, U.S. Gov&#039;t, P.H.S.
N1  - Lattimore, Keri A Donn, Steven M Kaciroti, Niko Kemper, Alex R Neal, Charles R Jr Vazquez, Delia M MH065062 (United States NIMH NIH HHS) MH068489 (United States NIMH NIH HHS)
PY  - 2005
SP  - 595-604
T2  - Journal of Perinatology
TI  - Selective serotonin reuptake inhibitor (SSRI) use during pregnancy and effects on the fetus and newborn: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=16015372
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:16015372&amp;id=doi:&amp;issn=0743-8346&amp;isbn=&amp;volume=25&amp;issue=9&amp;spage=595&amp;pages=595-604&amp;date=2005&amp;title=Journal+of+Perinatology&amp;atitle=Selective+serotonin+reuptake+inhibitor+%28SSRI%29+use+during+pregnancy+and+effects+on+the+fetus+and+newborn%3A+a+meta-analysis.&amp;aulast=Lattimore&amp;pid=%3Cauthor%3ELattimore+KA%3C%2Fauthor%3E%3CAN%3E16015372%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.nature.com/jp/journal/v25/n9/pdf/7211352a.pdf
UR  - http://www.nature.com/jp/journal/v25/n9/pdf/7211352a.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - This review examined the effectiveness of teacher-mediated interventions with respect to the academic functioning of students with emotional and behavioral disorders (EBD). Thirty studies using a variety of teacher-mediated interventions met the criteria for inclusion in this review. Findings from these studies indicate teacher-mediated interventions are successful across academic subject areas. However, the participant characteristics were defined poorly, and the settings used within these studies did not accurately reflect the current EBD population&#039;s actual classroom placement. Finally, a lack of programmatic research on teacher-mediated interventions has made it difficult, if not impossible, to generalize the outcomes of these studies to broader populations of students with EBD. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Pierce, Corey D.: coreypierce@yahoo.com Pierce, Corey D.: Center for At-Risk Children&#039;s Services, University of Nebraska, 202 Barkley Memorial Center, Lincoln, NE, US, 68583, coreypierce@yahoo.com Pierce, Corey D.: Department of Special Education and Communication Disorders, University of Nebraska, Lincoln, NE, US Reid, Robert: Department of Special Education and Communication Disorders, University of Nebraska, Lincoln, NE, US Epstein, Michael H.: Center for At-Risk Children&#039;s Services, University of Nebraska, Lincoln, NE, US
AN  - 2004-14678-004
AU  - Pierce,
AU  - C.
AU  - D.
AU  - Reid,
AU  - R.
AU  - Epstein,
AU  - M.
AU  - H.
DA  - May-Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/07419325040250030501
DP  - Ovid Technologies
KW  - teacher-mediated interventions, emotional and behavioral disorders, classroom placement, academic functioning *Behavior Disorders *Emotional Disturbances *School Based Intervention *Teachers Academic Achievement Educational Placement Special &amp; Remedial
LA  - English
M3  - Literature Review
PY  - 2004
SP  - 175-188
T2  - Remedial and Special Education
TI  - Teacher-mediated interventions for children with EBD and their academic outcomes: A Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2004-14678-004
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F07419325040250030501&amp;issn=0741-9325&amp;isbn=&amp;volume=25&amp;issue=3&amp;spage=175&amp;pages=175-188&amp;date=2004&amp;title=Remedial+and+Special+Education&amp;atitle=Teacher-mediated+interventions+for+children+with+EBD+and+their+academic+outcomes%3A+A+Review.&amp;aulast=Pierce&amp;pid=%3Cauthor%3EPierce%2C+Corey+D%3C%2Fauthor%3E%3CAN%3E2004-14678-004%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rse.sagepub.com/content/25/3/175http://rse.sagepub.com/content/25/3/175.full.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - **OBJECTIVES:** 
To evaluate the clinical and cost-effectiveness of quetiapine, olanzapine and valproate semisodium in the treatment of mania associated with bipolar disorder.

**DATA SOURCES:** 
Electronic databases; industry submissions made to the National Institute for Clinical Excellence.

**REVIEW METHODS:** 
Randomised trials and economic evaluations that evaluated the effectiveness of quetiapine, olanzapine or valproate semisodium in the treatment of mania associated with bipolar disorder were selected for inclusion. Data were extracted by one reviewer into a Microsoft Access database and checked for quality and accuracy by a second. The quality of the cost-effectiveness studies was assessed using a checklist updated from that developed by Drummond and colleagues. Relative risk and mean difference data were presented as Forest plots but only pooled where this made sense clinically and statistically. Studies were grouped by drug and, within each drug, by comparator used. Chi-squared tests of heterogeneity were performed for the outcomes if pooling was indicated. A probabilistic model was developed to estimate costs from the perspective of the NHS, and health outcomes in terms of response rate, based on an improvement of at least 50% in a patient&#039;s baseline manic symptoms derived from an interview-based mania assessment scale. The model evaluated the cost-effectiveness of the alternative drugs when used as part of treatment for the acute manic episode only.

**RESULTS:** 
Eighteen randomised trials met the inclusion criteria. Aspects of three of the quetiapine studies were commercial-in-confidence. The quality of the included trials was limited and overall, key methodological criteria were not met in most trials. Quetiapine, olanzapine and valproate semisodium appear superior to placebo in reducing manic symptoms, but may cause side-effects. There appears to be little difference between these treatments and lithium in terms of effectiveness, but quetiapine is associated with somnolence and weight gain, whereas lithium is associated with tremor. Olanzapine as adjunct therapy to mood stabilisers may be more effective than placebo in reducing mania and improving global health, but it is associated with more dry mouth, somnolence, weight gain, increased appetite, tremor and speech disorder. There was little difference between these treatments and haloperidol in reducing mania, but haloperidol was associated with more extrapyramidal side-effects and negative implications for health-related quality of life. Intramuscular olanzapine and lorazepam were equally effective and safe in one very short (24 hour) trial. Valproate semisodium and carbamazepine were equally effective and safe in one small trial in children. Olanzapine may be more effective than valproate semisodium in reducing mania, but was associated with more dry mouth, increased appetite, oedema, somnolence, speech disorder, Parkinson-like symptoms and weight gain. Valproate semisodium was associated with more nausea than olanzapine. The results from the base-case analysis demonstrate that choice of optimal strategy is dependent on the maximum that the health service is prepared to pay per additional responder. For a figure of less than 7179 British pounds per additional responder, haloperidol is the optimal decision; for a spend in excess of this, it would be olanzapine. Under the most favourable scenario in relation to the costs of responders and non-responders beyond the 3-week period considered in the base-case analysis, the incremental cost-effectiveness ratio of olanzapine is reduced to 1236 British pounds.

**CONCLUSIONS:** 
In comparison with placebo, quetiapine, olanzapine and valproate semisodium appear superior in reducing manic symptoms, but all drugs are associated with adverse events. In comparison with lithium, no significant differences were found between the three drugs in terms of effectiveness, and all were associated with adverse events. Several limitations of the cost-effectiveness analysis exist, which inevitably means that the results should be treated with some caution. There remains a need for well-conducted, randomised, double-blind head-to-head comparisons of drugs used in the treatment of mania associated with bipolar disorder and their cost-effectiveness. Participant demographic, diagnostic characteristics, the treatment of mania in children, the use of adjunctive therapy and long-term safety issues in the elderly population, and acute and long-term treatment are also subjects for further study. [References: 233]
AD  - Bridle, C. Centre for Reviews and Dissemination, University of York, UK.
AN  - 15147609
AU  - Bridle,
AU  - C.
AU  - Palmer,
AU  - S.
AU  - Bagnall,
AU  - A.
AU  - M.
AU  - Darba,
AU  - J.
AU  - Duffy,
AU  - S.
AU  - Sculpher,
AU  - M.
AU  - Riemsma,
AU  - R.
DB  - Rekoding IN SUM_lme.enl
DO  - 10.3310/hta8190
DP  - Ovid Technologies
J2  - Health Technol Assess
KW  - Antimanic Agents/ec [Economics]
KW  - Antimanic Agents/tu [Therapeutic Use]
KW  - *Antipsychotic Agents/ec [Economics]
KW  - *Antipsychotic Agents/tu [Therapeutic Use]
KW  - Benzodiazepines/ec [Economics]
KW  - Benzodiazepines/tu [Therapeutic Use]
KW  - *Bipolar Disorder/dt [Drug Therapy]
KW  - *Bipolar Disorder/ec [Economics]
KW  - Cost-Benefit Analysis
KW  - Dibenzothiazepines/ec [Economics]
KW  - Dibenzothiazepines/tu [Therapeutic Use]
KW  - Humans
KW  - Lithium/ec [Economics]
KW  - Lithium/tu [Therapeutic Use]
KW  - Olanzapine
KW  - Quetiapine Fumarate
KW  - Randomized Controlled Trials as Topic
KW  - Valproic Acid/ec [Economics]
KW  - Valproic Acid/tu [Therapeutic Use]
KW  - 0 (Antimanic Agents)
KW  - 0 (Antipsychotic Agents)
KW  - 0 (Dibenzothiazepines)
KW  - 12794-10-4 (Benzodiazepines)
KW  - 2S3PL1B6UJ (Quetiapine Fumarate)
KW  - 614OI1Z5WI (Valproic Acid)
KW  - 9FN79X2M3F (Lithium)
KW  - N7U69T4SZR (Olanzapine)
L1  - internal-pdf://1378886522/Bridle.pdf
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t
Review
Systematic Review
N1  - Bridle, CPalmer, SBagnall, A-MDarba, JDuffy, SSculpher, MRiemsma, R
PY  - 2004
SP  - iii-iv, 1-187
T2  - Health Technology Assessment (Winchester, England)
TI  - A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=15147609
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15147609&amp;id=doi:10.3310%2Fhta8190&amp;issn=1366-5278&amp;isbn=&amp;volume=8&amp;issue=19&amp;spage=iii&amp;pages=iii-iv%2C+1-187&amp;date=2004&amp;title=Health+Technology+Assessment+%28Winchester%2C+England%29&amp;atitle=A+rapid+and+systematic+review+and+economic+evaluation+of+the+clinical+and+cost-effectiveness+of+newer+drugs+for+treatment+of+mania+associated+with+bipolar+affective+disorder.&amp;aulast=Bridle&amp;pid=%3Cauthor%3EBridle+C%3C%2Fauthor%3E%3CAN%3E15147609%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 8
ER  -
TY  - JOUR
AB  - Research has shown that peer-mediated interventions produce positive academic outcomes for a wide range of students, The authors of this review examined the effectiveness of peer-mediated interventions on the academic functioning of students with emotional and behavior disorders (EBD). Fourteen studies using cross-age, same-age, classwide peer tutoring, or cooperative learning met the criteria set forth for this review. Findings from these studies indicate peer-mediated interventions were successful across academic subject areas and grade levels. However, the participants and settings used within these studies did not accurately reflect the current EBD population&#039;s ethnic or gender composition or actual classroom placement. Finally, despite the recent growth in the number of students identified with EBD, the number of research studies investigating academic interventions has declined. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Ryan, Joseph B.: Joe_ryan1@hotmail.com Ryan, Joseph B.: Center for At-Risk Children&#039;s Services, University of Nebraska, 202 Barkley Memorial Center, Lincoln, NE, US, 68583, Joe_ryan1@hotmail.com Ryan, Joseph B.: University of Nebraska, Lincoln, NE, US Reid, Robert: Department of Special Education and Communication Disorders, University of Nebraska, Lincoln, NE, US Epstein, Michael H.: Center for At-Risk Children&#039;s Services, University of Nebraska, Lincoln, NE, US
AN  - 2004-21886-001
AU  - Ryan,
AU  - J.
AU  - B.
AU  - Reid,
AU  - R.
AU  - Epstein,
AU  - M.
AU  - H.
DA  - Nov-Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/07419325040250060101
DP  - Ovid Technologies
KW  - peer mediated intervention, academic achievement &amp; functioning, emotional and behavior disorders, intervention effectiveness *Academic Achievement *Behavior Disorders *Emotional Disturbances *Peer Tutoring *School Based Intervention Program Evaluation S
LA  - English
M3  - Literature Review
PY  - 2004
SP  - 330-341
T2  - Remedial and Special Education
TI  - Peer-Mediated Intervention Studies on Academic Achievement for Students with EBD: A Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2004-21886-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F07419325040250060101&amp;issn=0741-9325&amp;isbn=&amp;volume=25&amp;issue=6&amp;spage=330&amp;pages=330-341&amp;date=2004&amp;title=Remedial+and+Special+Education&amp;atitle=Peer-Mediated+Intervention+Studies+on+Academic+Achievement+for+Students+with+EBD%3A+A+Review.&amp;aulast=Ryan&amp;pid=%3Cauthor%3ERyan%2C+Joseph+B%3C%2Fauthor%3E%3CAN%3E2004-21886-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rse.sagepub.com/content/25/6/330http://rse.sagepub.com/content/25/6/330.full.pdf
VL  - 25
ER  -
TY  - JOUR
AB  - **Background:** 
Antipsychotics are commonly prescribed for women suffering psychotic illnesses during pregnancy and the postpartum period. The potential adverse consequences of these different options are multiple and complex, impacting on the foetus, neonate, infant and early development of the child as well as the woman herself.

**Objectives:** 
To establish whether the benefits of taking antipsychotic drugs outweigh the risks for pregnant or post partum women.

**Search methods:** 
The Cochrane Schizophrenia Group&#039;s Register (January 2003) was searched in order to identify all published trials of women during pregnancy or the postpartum period. We inspected all references of all identified studies. If any studies had been found, the first authors of each included study would have been contacted.

**Selection criteria:** 
Randomised controlled clinical trials investigating the effects of any type of antipsychotic drug compared with any other treatment option (including standard psychosocial care, any other antipsychotic drug, or an alternative therapy such as electro-convulsive therapy or cognitive behavioural therapy) and involving pregnant women and/or women during the postpartum period diagnosed with a non-affective psychotic disorder.

**Data collection and analysis:** 
Citations, and where possible, abstracts were independently inspected by reviewers and the papers ordered were scrutinised and quality assessed. Data would have been extracted independently by at least two reviewers. Binary outcomes were to have been analysed using Relative Risks (RR) and their 95% Confidence Intervals (CI).

**Main results:**
We found no trials that met the broad inclusion criteria.

**Authors&#039; conclusions:** 
Current guidelines and clinical practice for the use of antipsychotic drugs in women with non-affective disorders during pregnancy and postpartum are not based on evidence from randomised controlled trials. Although ethical concerns have to date precluded the use of randomised controlled trials to address this research topic, the continued use of antipsychotic drugs in this group of women in itself poses significant clinical and ethical problems. Evidence is required from large pragmatic trials that reflect routine clinical practice, examine a broad range of outcomes and accurately quantify risks and benefits to both mothers and their offspring, so that comparison between different treatment options can be made.
AN  - CD004411
AU  - Webb,
AU  - R.
AU  - T.
AU  - Howard,
AU  - L.
AU  - Abel,
AU  - K.
AU  - M.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004411
KW  - Antipsychotic Agents [therapeutic use]
KW  - Pregnancy Complications [drug therapy] [psychology]
KW  - Psychotic Disorders [drug therapy]
KW  - Puerperal Disorders [drug therapy] [psychology]
KW  - Female[checkword]
KW  - Humans[checkword]
KW  - Pregnancy[checkword]
KW  - Schiz
PY  - 2004
T2  - Cochrane Database of Systematic Reviews
TI  - Antipsychotic drugs for non-affective psychosis during pregnancy and postpartum
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004411.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004411.pub2/asset/CD004411.pdf?v=1&amp;t=iw7iqq17&amp;s=f0894831373acf7f3fe2c077d46b7dd5c9212271
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To review the literature on the cognitive-behavioral treatment of children and adolescents with anxiety and depressive disorders within the conceptual framework of evidence-based medicine. 

**METHOD: **
The psychiatric and psychological literature was systematically searched for controlled trials applying cognitive-behavioral treatment to pediatric anxiety and depressive disorders. 

**RESULTS: **
For both anxiety and depression, substantial evidence supports the efficacy of problem-specific cognitive-behavioral interventions. Comparisons with wait-list, inactive control, and active control conditions suggest medium to large effects for symptom reduction in primary outcome domains. 

**CONCLUSIONS: **
From an evidence-based perspective, cognitive-behavioral therapy is currently the treatment of choice for anxiety and depressive disorders in children and adolescents. Future research in this area will need to focus on comparing cognitive-behavioral psychotherapy with other treatments, component analyses, and the application of exportable protocol-driven treatments to divergent settings and patient populations.
AD  - Compton,Scott N. Department of Psychiatry and Behavioral Psychology, Duke University Medical Center, Durham, NC 27710, USA. scompton@duke.edu
AN  - 15266189
AU  - Compton,
AU  - S.
AU  - N.
AU  - March,
AU  - J.
AU  - S.
AU  - Brent,
AU  - D.
AU  - 5th
AU  - Albano,
AU  - A.
AU  - M.
AU  - Weersing,
AU  - R.
AU  - Curry,
AU  - J.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pubmed/15266189
DP  - Ovid Technologies
J2  - J Am Acad Child Adolesc Psychiatry
KW  - Adolescent Anxiety Disorders/di [Diagnosis] Anxiety Disorders/px [Psychology] *Anxiety Disorders/th [Therapy] Child *Cognitive Therapy Controlled Clinical Trials as Topic Depressive Disorder/di [Diagnosis] Depressive Disorder/px [Psychology] *Depressive
LA  - English
M3  - Review
N1  - Compton, Scott N March, John S Brent, David Albano, Anne Marie 5th Weersing, Robin Curry, John Comment in: J Am Acad Child Adolesc Psychiatry. 2005 Sep;44(9):841; author reply 841-3; PMID: 16113610
PY  - 2004
SP  - 930-59
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Cognitive-behavioral psychotherapy for anxiety and depressive disorders in children and adolescents: an evidence-based medicine review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=15266189 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15266189&amp;id=doi:&amp;issn=0890-8567&amp;isbn=&amp;volume=43&amp;issue=8&amp;spage=930&amp;pages=930-59&amp;date=2004&amp;title=Journal+of+the+American+Academy+of+Child+%26+Adolescent+Psychiatry&amp;atitle=Cognitive-behavioral+psychotherapy+for+anxiety+and+depressive+disorders+in+children+and+adolescents%3A+an+evidence-based+medicine+review.&amp;aulast=Compton&amp;pid=%3Cauthor%3ECompton+SN%3C%2Fauthor%3E%3CAN%3E15266189%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://graphics.tx.ovid.com/ovftpdfs/FPDDNCLBFDFJAN00/fs047/ovft/live/gv024/00004583/00004583-200408000-00005.pdf
VL  - 43
ER  -
TY  - JOUR
AB  - **Purpose. **
To review the effectiveness of cognitive behaviour therapy (CBT) as a treatment for anxiety disorders of childhood and adolescence. 

**Method. **
Studies were included if they treated young people (under 19 yrs) with diagnosed anxiety disorder (excluding trials solely treating phobia, PTSD or OCD), had a no-treatment control group, and used diagnosis as an outcome variable. A search of the literature, incorporating electronic databases, hand search and expert consultation, yielded 10 randomized controlled trials that were appropriate for inclusion. 

**Results. **
The outcome of interest was remission. of anxiety disorder. Employing conservative criteria, the remission rate in the CBT groups (56.5%) was higher than that in the control groups (34.8%). The pooled odds ratio was 3.3 (Cl = 1.9-5.6), suggesting that CBT has a significant effect. 

**Conclusions. **
CBT is useful for the treatment of anxiety in children over the age of 6 years. However, we still know little about the treatment of younger children or about the comparative efficacy of alternative treatments. Most of the trials were efficacy trials, and have limited generalizability. Reporting of many aspects of the trials was weak.
AD  - Univ Manchester, Dept Child &amp; Adolescent Psychiat, Manchester, Lancs, England. Univ Manchester, Biostat Grp, Sch Epidemiol &amp; Hlth Sci, Manchester, Lancs, England. Univ Manchester, Div Clin Psychol, Manchester, Lancs, England. Cartwright-Hatton, S (reprint author), Royal Manchester Childrens Hosp, Univ Dept Child &amp; Adolescent Psychiat, Manchester M27 4HA, Lancs, England.
AN  - WOS:000225432900007
AU  - Cartwright-Hatton,
AU  - S.
AU  - Roberts,
AU  - C.
AU  - Chitsabesan,
AU  - P.
AU  - Fothergill,
AU  - C.
AU  - Harrington,
AU  - R.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1348/0144665042388928
J2  - Br. J. Clin. Psychol.
KW  - RANDOMIZED CLINICAL-TRIAL SCHOOL REFUSAL CHILDREN METAANALYSIS PREVENTION PHOBIA FAMILY Psychology, Clinical
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 875PK Times Cited: 136 Cited Reference Count: 33 Cartwright-Hatton, S Roberts, C Chitsabesan, P Fothergill, C Harrington, R 137 BRITISH PSYCHOLOGICAL SOC LEICESTER BRIT J CLIN PSYCHOL 4
PY  - 2004
SP  - 421-436
T2  - British Journal of Clinical Psychology
TI  - Systematic review of the efficacy of cognitive behaviour therapies for childhood and adolescent anxiety disorders
UR  - &lt;Go to ISI&gt;://WOS:000225432900007http://media.proquest.com/media/pq/classic/doc/757820821/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Cartwright-Hatton%2C+Sam%3BRoberts%2C+Chris%3BPrathiba+Chitsabesan%3BFothergill%2C+Claire%3BHarrington%2C+Richard&amp;cit%3Atitle=Systematic+review+of+the+efficacy+of+cognitive+behaviour+therapies+...&amp;cit%3Apub=The+British+Journal+of+Clinical+Psychology&amp;cit%3Avol=43&amp;cit%3Aiss=&amp;cit%3Apg=421&amp;cit%3Adate=Nov+2004&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYyMjA2MzQ0MzIxNDoyODMyNzMSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFMzgxODEyCTIxODYyNDQ2ODoNRG9jdW1lbnRJbWFnZUIBMFIGT25saW5lWgJGVGIDUEZUagoyMDA0LzExLzAxcgoyMDA0LzExLzMwegCCASlQLTEwMDAyNzMtMzEwNzUtQ1VTVE9NRVItMTAwMDAxNTctMTExNTExMpIBBk9ubGluZcoBB0VuZE5vdGXSARJTY2hvbGFybHkgSm91cm5hbHOaAgdQcmVQYWlkqgIoT1M6RU1TLVBkZkRvY1ZpZXdCYXNlLWdldE1lZGlhVXJsRm9ySXRlbcoCI0dlbmVyYWwgSW5mb3JtYXRpb258RmVhdHVyZXxBcnRpY2xl0gIBWeICAU7yAgA%3D&amp;_s=ymEogShlHeJEw6Oae3A%2FVHyJNxk%3D
VL  - 43
ER  -
TY  - JOUR
AB  - **Background**
Questions concerning the safety of selective serotonin reuptake inhibitors (SSRls) in the treatment of depression in children led us to compare and contrast published and unpublished data on the risks and benefits of these drugs. 

**Methods** 
We did a meta-analysis of data from randomised controlled trials that evaluated an SSRI versus placebo in participants aged 5-18 years and that were published in a peer-reviewed journal or were unpublished and included in a review by the Committee on Safety of Medicines. The following outcomes were included: remission, response to treatment, depressive symptom scores, serious adverse events, suicide-related behaviours, and discontinuation of treatment because of adverse events. 

**Findings** 
Data for two published trials suggest that fluoxetine has a favourable risk-benefit profile, and unpublished data lend support to this finding. Published results from one trial of paroxetine and two trials of sertraline suggest equivocal or weak positive risk-benefit profiles. However, in both cases, addition of unpublished data indicates that risks outweigh benefits. Data from unpublished trials of citalopram and venlafaxine show unfavourable risk-benefit profiles. Interpretation Published data suggest a favourable risk-benefit profile for some SSRIs; however, addition of unpublished data indicates that risks could outweigh benefits of these drugs (except fluoxetine) to treat depression in children and young people. Clinical guideline development and clinical decisions about treatment are largely dependent on an evidence base published in peer-reviewed journals. Non-publication of trials, for whatever reason, or the omission of important data from published trials, can lead to erroneous recommendations for treatment. Greater openness and transparency with respect to all intervention studies is needed.
AD  - UCL, Ctr Outcomes Res &amp; Effectiveness, Subdept Clin Hlth Psychol, London WC1E 7HB, England. Royal Coll Psychiatrists, Res Unit, London SW1H 0HW, England. Univ Leeds, Sch Med, Acad Unit Child &amp; Adolescent Mental Hlth, Leeds LS2 9JT, W Yorkshire, England. Pine Lodge Young Peoples Ctr, Chester, Cheshire, England. Whittington, CJ (reprint author), UCL, Ctr Outcomes Res &amp; Effectiveness, Subdept Clin Hlth Psychol, 1-19 Torrington Pl, London WC1E 7HB, England. c.whittington@ucl.ac.uk
AN  - WOS:000220996300007
AU  - Whittington,
AU  - C.
AU  - J.
AU  - Kendall,
AU  - T.
AU  - Fonagy,
AU  - P.
AU  - Cottrell,
AU  - D.
AU  - Cotgrove,
AU  - A.
AU  - Boddington,
AU  - E.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/s0140-6736(04)16043-1
J2  - Lancet
KW  - PHARMACEUTICAL-INDUSTRY MAJOR DEPRESSION CONTROLLED TRIAL CHILDREN ADOLESCENTS DISORDER FLUOXETINE SERTRALINE EFFICACY Medicine, General &amp; Internal
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 814TF Times Cited: 509 Cited Reference Count: 29 Whittington, CJ Kendall, T Fonagy, P Cottrell, D Cotgrove, A Boddington, E Whittington, Craig/B-1380-2008; Cottrell, David/A-1211-2013 Whittington, Craig/0000-0002-1950-0334; Cottrell, David/0000-0001-8674-0955 513 ELSEVIER SCIENCE INC NEW YORK LANCET
PY  - 2004
SP  - 1341-1345
T2  - Lancet
TI  - Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data
UR  - &lt;Go to ISI&gt;://WOS:000220996300007http://ac.els-cdn.com/S0140673604160431/1-s2.0-S0140673604160431-main.pdf?_tid=264c9126-1679-11e5-b50b-00000aab0f6b&amp;acdnat=1434714709_70698327cb34704c0f62f9230ecbb7f8
VL  - 363
ER  -
TY  - JOUR
AB  - This meta-analysis of eating disorder prevention programs found that intervention effects ranged from an absence of any effects to reductions in current and future eating pathology. Certain effects persisted as long as 2 years and were superior to minimal-intervention control conditions. Larger effects occurred for selected (vs. universal), interactive (vs. didactic), and multisession (vs. single session) programs; for programs offered solely to females and to participants over age 15; for programs without psychoeducational content; and for trials that used validated measures. The results identify promising prevention programs and delineate sample, format, and design features that are associated with larger effects, but they suggest the need for improved methodological rigor and statistical modeling of trials and enhanced theoretical rationale for interventions. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Stice, Eric: stice@psy.utexas.edu Stice, Eric: Department of Psychology, University of Texas, Austin, TX, US, 78712, stice@psy.utexas.edu Stice, Eric: Department of Psychology, University of Texas at Austin, Austin, TX, US Shaw, Heather: Department of Psychology, University of Texas at Austin, Austin, TX, US
AN  - 2004-11156-002
AU  - Stice,
AU  - E.
AU  - Shaw,
AU  - H.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1037/0033-2909.130.2.206
DP  - Ovid Technologies
KW  - eating disorders, prevention programs, intervention effects, eating pathology *Eating Disorders *Intervention *Prevention *Program Evaluation *Treatment Outcomes Pathology Eating Disorders [3260] Human Female Adolescence (13-17 yrs) Adulthood (18 yrs &amp;
LA  - English
M3  - Empirical Study; Meta Analysis
PY  - 2004
SP  - 206-227
T2  - Psychological Bulletin
TI  - Eating Disorder Prevention Programs: A Meta-Analytic Review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2004-11156-002
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2F0033-2909.130.2.206&amp;issn=0033-2909&amp;isbn=&amp;volume=130&amp;issue=2&amp;spage=206&amp;pages=206-227&amp;date=2004&amp;title=Psychological+Bulletin&amp;atitle=Eating+Disorder+Prevention+Programs%3A+A+Meta-Analytic+Review.&amp;aulast=Stice&amp;pid=%3Cauthor%3EStice%2C+Eric%3C%2Fauthor%3E%3CAN%3E2004-11156-002%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://psycnet.apa.org/journals/bul/130/2/206.pdf
VL  - 130
ER  -
TY  - JOUR
AB  - **Background:** 
Nocturnal enuresis (bedwetting) is a socially disruptive and stressful condition which affects around 15 to 20% of five-year olds, and up to 2% of young adults.

**Objectives:** 
To assess the effects of complex behavioural and educational interventions on nocturnal enuresis in children, and to compare them with other interventions.Search methods: We searched the Cochrane Incontinence Group Specialised Trials Register (searched 20 March 2008) and the reference lists of relevant articles.

**Selection criteria:** 
All randomised or quasi-randomised trials of complex behavioural or educational interventions for nocturnal enuresis in children were included, except those focused solely on daytime wetting. Comparison interventions included no treatment, simple and physical behavioural methods, alarms, desmopressin, tricyclic antidepressants, and miscellaneous other interventions.

**Data collection and analysis:** 
Two review authors independently assessed the quality of the eligible trials, and extracted data.

**Main results:** 
Eighteen trials involving 1174 children were identified which included a complex or educational intervention for nocturnal enuresis. The trials were mostly small and some had methodological problems including the use of a quasi-randomised method of concealment of allocation in three trials and baseline differences between the groups in another three.A complex intervention (such as dry bed training (DBT) or full spectrum home training (FSHT)) including an alarm was better than no-treatment control groups (for example the relative risk (RR) for failure or relapse after stopping DBT was 0.25; 95% CI 0.16 to 0.39) but there was not enough evidence about the effects of complex interventions alone if an alarm was not used. A complex intervention on its own was not as good as an alarm on its own or the intervention supplemented by an alarm (e.g. RR for failure or relapse after DBT alone versus DBT plus alarm was 2.81; 95% CI 1.80 to 4.38). On the other hand, a complex intervention supplemented by a bed alarm might reduce the relapse rate compared with the alarm on its own (e.g. RR for failure or relapse after DBT plus alarm versus alarm alone was 0.5; 95% CI 0.31 to 0.80).There was not enough evidence to judge whether providing educational information about enuresis was effective, irrespective of method of delivery. There was some evidence that direct contact between families and therapists enhanced the effect of a complex intervention, and that increased contact and support enhanced a package of simple behavioural interventions, but these were addressed only in single trials and the results would need to be confirmed by further randomised controlled trials, in particular the effect on use of resources.

**Authors&#039; conclusions:**
Although DBT and FSHT were better than no treatment when used in combination with an alarm, there was insufficient evidence to support their use without an alarm. An alarm on its own was also better than DBT on its own, but there was some evidence that combining an alarm with DBT was better than an alarm on its own, suggesting that DBT may augment the effect of an alarm. There was also some evidence that direct contact with a therapist might enhance the effects of an intervention.
AN  - CD004668
AU  - Glazener,
AU  - C.
AU  - M.
AU  - Evans,
AU  - J.
AU  - H.
AU  - Peto,
AU  - R.
AU  - E.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd004668
KW  - Patient Education as Topic
KW  - Behavior Therapy [methods]
KW  - Enuresis [therapy]
KW  - Exercise Therapy [methods]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Incont
PY  - 2004
T2  - Cochrane Database of Systematic Reviews
TI  - Complex behavioural and educational interventions for nocturnal enuresis in children
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD004668/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD004668/asset/CD004668.pdf?v=1&amp;t=iw7j6ziw&amp;s=5c692bdefbef05c45f926da7197254f8d3d32656
ER  -
TY  - JOUR
AB  - **Background:** 
It has been argued that infants in Neonatal Intensive Care Units are subject both to a highly stressful environment - continuous, high-intensity noise and bright light - and to a lack of the tactile stimulation that they would otherwise experience in the womb or in general mothering care. As massage seems to both decrease stress and provide tactile stimulation, it has been recommended as an intervention to promote growth and development of preterm and low-birth weight infants.

**Objectives:** 
To determine whether preterm and/or low birth-weight infants exposed to massage experience improved weight gain and earlier discharge compared to infants receiving standard care; to determine whether massage has any other beneficial or harmful effects on this population.

**Search methods:** 
The following databases were searched: the specialized register of the Cochrane Neonatal Review Group and that of the Cochrane Complementary Medicine Field. Searches were also undertaken of the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, Issue 3, 2003), MEDLINE, EMBASE, Psychlit, CINAHL and Dissertation Abstracts International (up to July 1, 2003). Further references were obtained by citation tracking, checking personal files and by correspondence with appropriate experts. Data provided in published reports was supplemented by information obtained by correspondence with authors. There were no language restrictions.

**Selection criteria:**
Randomised trials in which infants with gestational age at birth &lt;37 weeks or weight at birth &lt;2500g received systematic tactile stimulation by human hands. At least one outcome assessing weight gain, length of stay, behaviour or development must be reported.

**Data collection and analysis:** 
Data extracted from each trial were baseline characteristics of sample, weight gain, length of stay and behavioural and developmental outcomes. Physiological and biochemical outcomes were not recorded. Data were extracted by three reviewers independently. Statistical analysis was conducted using the standard Cochrane Collaboration methods.

**Main results:** 
Massage interventions improved daily weight gain by 5.1g (95% CI 3.5, 6.7g). There is no evidence that gentle, still touch is of benefit (increase in daily weight gain 0.2g; 95% CI -1.2, 1.6g). Massage interventions also appeared to reduce length of stay by 4.5 days (95% CI 2.4, 6.5) though there are methodological concerns about the blinding of this outcome. There was also some evidence that massage interventions have a slight, positive effect on postnatal complications and weight at 4 - 6 months. However, serious concerns about the methodological quality of the included studies, particularly with respect to selective reporting of outcomes, weaken credibility in these findings.

**Authors&#039; conclusions:** 
Evidence that massage for preterm infants is of benefit for developmental outcomes is weak and does not warrant wider use of preterm infant massage. Where massage is currently provided by nurses, consideration should be given as to whether this is a cost-effective use of time. Future research should assess the effects of massage interventions on clinical outcome measures, such as medical complications or length of stay, and on process-of-care outcomes, such as care-giver or parental satisfaction.
AN  - CD000390
AU  - Vickers,
AU  - A.
AU  - Ohlsson,
AU  - A.
AU  - Lacy,
AU  - J.
AU  - Horsley,
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd000390
KW  - Infant Care
KW  - Massage
KW  - Infant, Low Birth Weight [growth &amp; development]
KW  - Infant, Newborn
KW  - Infant, Premature [growth &amp; development]
KW  - Physical Stimulation
KW  - Weight Gain
KW  - Humans[checkword]
KW  - Neonatal
PY  - 2004
T2  - Cochrane Database of Systematic Reviews
TI  - Massage for promoting growth and development of preterm and/or low birth-weight infants
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD000390.pub2/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD000390.pub2/asset/CD000390.pdf?v=1&amp;t=iw7k1i7n&amp;s=1a60d8f9f5abc4eb539c39b6c57e06ce99602299
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
The objectives of this review were to examine the overall efficacy of music therapy for children and adolescents with psychopathology, and to examine how the size of the effect of music therapy is influenced by the type of pathology, client&#039;s age, music therapy approach, and type of outcome. 

**METHOD: **
Eleven studies were included for analysis, which resulted in a total of 188 subjects for the meta-analysis. Effect sizes from these studies were combined, with weighting for sample size, and their distribution was examined. 

**RESULTS: **
After exclusion of an extreme positive outlying value, the analysis revealed that music therapy has a medium to large positive effect (ES =.61) on clinically relevant outcomes that was statistically highly significant (p &lt;.001) and statistically homogeneous. No evidence of a publication bias was identified. Effects tended to be greater for behavioural and developmental disorders than for emotional disorders; greater for eclectic, psychodynamic, and humanistic approaches than for behavioural models; and greater for behavioural and developmental outcomes than for social skills and self-concept.

**CONCLUSIONS: **
Implications for clinical practice and research are discussed.
AD  - Gold,Christian. Faculty of Health Studies, Sogn og Fjordane University College, Sandane, Norway. christian.gold@hisf.no
AN  - 15257662
AU  - Gold,
AU  - C.
AU  - Voracek,
AU  - M.
AU  - Wigram,
AU  - T.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1469-7610.2004.t01-1-00298.x
DP  - Ovid Technologies
J2  - J Child Psychol Psychiatry
KW  - Adolescent Child *Child Behavior Disorders/th [Therapy] Humans *Music Therapy/mt [Methods]
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Gold, Christian Voracek, Martin Wigram, Tony
PY  - 2004
SP  - 1054-63
T2  - Journal of Child Psychology and Psychiatry and Allied Disciplines
TI  - Effects of music therapy for children and adolescents with psychopathology: a meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=15257662 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15257662&amp;id=doi:&amp;issn=0021-9630&amp;isbn=&amp;volume=45&amp;issue=6&amp;spage=1054&amp;pages=1054-63&amp;date=2004&amp;title=Journal+of+Child+Psychology+%26+Psychiatry+%26+Allied+Disciplines&amp;atitle=Effects+of+music+therapy+for+children+and+adolescents+with+psychopathology%3A+a+meta-analysis.&amp;aulast=Gold&amp;pid=%3Cauthor%3EGold+C%3C%2Fauthor%3E%3CAN%3E15257662%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1469-7610.2004.t01-1-00298.x/asset/j.1469-7610.2004.t01-1-00298.x.pdf?v=1&amp;t=ib8zz1og&amp;s=b8ee734f1eeef6686cdc5f56d80832473b999bc4
VL  - 45
ER  -
TY  - JOUR
AB  - Background
Psychological and behavioural problems in children and adolescents are common, and improving self‐esteem may help to prevent the development of such problems. There is strong evidence for the positive physical health outcomes of exercise, but the evidence of exercise on mental health is scarce.

Objectives
To determine if exercise alone or exercise as part of a comprehensive intervention can improve self‐esteem among children and young people.

Search methods
Computerised searches in MEDLINE, EMBASE, The Cochrane Controlled Trials Register (CENTRAL), CINAHL, PsycINFO and ERIC were undertaken and reference lists from relevant articles were scanned. Relevant studies were also traced by contacting authors. Dates of most recent searches: May 2003 in (CENTRAL), all others: January 2002.

Selection criteria
Randomised controlled trials where the study population consisted of children and young people aged from 3 to 20 years, in which one intervention arm was gross motor activity for more than four weeks and the outcome measure was self‐esteem.

Data collection and analysis
Two reviewers independently selected trials for inclusion, assessed the validity of included trials and extracted data. Investigators were contacted to collect missing data or for clarification when necessary.

Main results
Twenty‐three trials with a total of 1821 children and young people were included. Generally, the trials were small, and only one was assessed to have a low risk of bias. Thirteen trials compared exercise alone with no intervention. Eight were included in the meta‐analysis, and overall the results were heteregeneous. One study with a low risk of bias showed a standardised mean difference (SMD) of 1.33 (95% CI 0.43 to 2.23), while the SMD&#039;s for the three studies with a moderate risk of bias and the four studies with a high risk of bias was 0.21 (95% CI ‐0.17 to 0.59) and 0.57 (95% CI 0.11 to 1.04), respectively. Twelve trials compared exercise as part of a comprehensive programme with no intervention. Only four provided data sufficient to calculate overall effects, and the results indicate a moderate short‐term difference in self‐esteem in favour of the intervention [SMD 0.51 (95% CI 0.15 to 0.88)].

Authors&#039; conclusions
The results indicate that exercise has positive short‐term effects on self‐esteem in children and young people. Since there are no known negative effects of exercise and many positive effects on physical health, exercise may be an important measure in improving children&#039;s self‐esteem. 
These conclusions are based on several small low‐quality trials.
AU  - Ekeland,
AU  - E.
AU  - Heian,
AU  - F.
AU  - Hagen,
AU  - K.
AU  - B.
AU  - Abbott,
AU  - J.
AU  - Nordheim,
AU  - L.
AU  - V.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
KW  - Children (age group)
KW  - Self esteem
KW  - Exercise
KW  - Youth
KW  - Adolescents
PY  - 2004
TI  - Exercise to Improve Self-Esteem in Children and Young People: A Systematic Review
ER  -
TY  - JOUR
AB  - Sleep disturbances in children with neurodevelopmental disabilities are common and frequently difficult to treat with conventional pharmacological and behavioural methods. 

Melatonin is a pineal hormone known to be important in the regulation of the circadian rhythm, including the sleep-wake cycle. This systematic review of available evidence from randomized clinical trials assesses whether melatonin plays a beneficial role in these children and, in particular, its effect on total sleep time, time to sleep onset (sleep latency), and number of awakenings. 

We also looked at a parental view of the effect. Randomized clinical trials were identified where oral melatonin was compared with a placebo in children with any type of neurodevelopmental disability and associated sleep disturbance. 

Only three studies, reporting a total of 35 children, fulfilled the criteria for inclusion. The two studies that reported time to sleep onset showed a significant decrease (p&lt;0.05) in this specific outcome where melatonin was compared with a placebo. 

There was no significant effect of melatonin compared with a placebo on the other outcome measures of total sleep time, night-time awakenings, and parental opinions. Despite the extremely limited randomized clinical trial data, melatonin appears to remain a commonly prescribed drug for disturbed sleep in children with neurodevelopmental abnormalities.
AD  - Phillips,Louise. Department of Neurology, Royal Liverpool Children&#039;s NHS Trust, Liverpool L12 2AP, UK.
AN  - 15540639
AU  - Phillips,
AU  - L.
AU  - Appleton,
AU  - R.
AU  - E
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1111/j.1469-8749.2004.tb00998.x
DP  - Ovid Technologies
J2  - Dev Med Child Neurol
KW  - *Antioxidants/tu [Therapeutic Use] *Brain/pp [Physiopathology] Child *Developmental Disabilities/dt [Drug Therapy] Developmental Disabilities/ep [Epidemiology] *Developmental Disabilities/pp [Physiopathology] Humans *Melatonin/tu [Therapeutic Use] Sleep
LA  - English
M3  - Meta-Analysis Review
N1  - Phillips, Louise Appleton, Richard E Comment in: Dev Med Child Neurol. 2008 Jul;50(7):558; PMID: 18611209 Comment in: Dev Med Child Neurol. 2004 Nov;46(11):723; PMID: 15540631
PY  - 2004
SP  - 771-5
T2  - Developmental Medicine and Child Neurology
TI  - Systematic review of melatonin treatment in children with neurodevelopmental disabilities and sleep impairment
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med5&amp;AN=15540639 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:15540639&amp;id=doi:&amp;issn=0012-1622&amp;isbn=&amp;volume=46&amp;issue=11&amp;spage=771&amp;pages=771-5&amp;date=2004&amp;title=Developmental+Medicine+%26+Child+Neurology&amp;atitle=Systematic+review+of+melatonin+treatment+in+children+with+neurodevelopmental+disabilities+and+sleep+impairment.&amp;aulast=Phillips&amp;pid=%3Cauthor%3EPhillips+L%3C%2Fauthor%3E%3CAN%3E15540639%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://onlinelibrary.wiley.com/store/10.1111/j.1469-8749.2004.tb00998.x/asset/j.1469-8749.2004.tb00998.x.pdf?v=1&amp;t=ib7vnuxe&amp;s=119107a256dc5ba5100db5eb26e7e8d4abca3875
VL  - 46
ER  -
TY  - JOUR
AB  - **Objective:** 
A synthesis was conducted to assess outcome findings and methodological characteristics of controlled evaluations of adolescent substance abuse treatments. 

**Method:** 
Extensive computerized and manual bibliographic searches were employed to identify controlled evaluations of adolescent substance abuse treatment. Meta-analytic techniques were utilized to gauge effect sizes across studies to determine which interventions are most effective. An index of methodological quality was computed for each study using ratings of 13 study design factors. Interventions were classified by a combination of their design strength, achievement of desired effect, and other evidence factors. 

**Results:** 
Findings indicate that multidimensional family therapy and cognitive-behavioral group treatment received the highest level of evidentiary support. Seven other interventions showed evidence of effectiveness as well. 

**Conclusions: **
Several interventions are effective for treating adolescent substance abuse. These treatments are psycho-social in nature, exist within a structured framework, and should be appealing to social work practitioners.
AD  - Washington Univ, George Warren Brown Sch Social Work, Comorbid &amp; Addict Ctr, St Louis, MO 63130 USA. Vaughn, MG (reprint author), Washington Univ, George Warren Brown Sch Social Work, Comorbid &amp; Addict Ctr, St Louis, MO 63130 USA. mvaughn@gwbmail.wustl.edu
AN  - WOS:000223109700002
AU  - Vaughn,
AU  - M.
AU  - G.
AU  - Howard,
AU  - M.
AU  - O.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/1049731504265834
J2  - Res. Soc. Work. Pract.
KW  - substance abuse treatments evidence-based practice family based adolescents court-referred youth FAMILY-THERAPY DRUG-ABUSE JUVENILE-OFFENDERS FOLLOW-UP PSYCHOTHERAPIES DEPENDENCE PROGRAM TRIALS Social Work
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 843TO Times Cited: 50 Cited Reference Count: 37 Vaughn, MG Howard, MO 51 SAGE PUBLICATIONS INC THOUSAND OAKS RES SOCIAL WORK PRAC
PY  - 2004
SP  - 325-335
T2  - Research on Social Work Practice
TI  - Adolescent substance abuse treatment: A synthesis of controlled evaluations
UR  - &lt;Go to ISI&gt;://WOS:000223109700002http://rsw.sagepub.com/content/14/5/325http://rsw.sagepub.com/content/14/5/325.full.pdf
VL  - 14
ER  -
TY  - JOUR
AB  - Bullying is a serious problem in schools, and school authorities need effective solutions to resolve this problem. There is growing interest in the whole-school approach to bullying. Whole-school programs have multiple components that operate simultaneously at different levels in the school community. 

This article synthesizes the existing evaluation research on whole-school programs to determine the overall effectiveness of this approach. The majority of programs evaluated to date have yielded nonsignificant outcomes on measures of self-reported victimization and bullying, and only a small number have yielded positive outcomes. 

On the whole, programs in which implementation was systematically monitored tended to be more effective than programs without any monitoring.
AD  - Univ Ottawa, Fac Educ, Ottawa, ON K1N 6N5, Canada. Univ London, London WC1E 7HU, England. Smith, JD (reprint author), Univ Ottawa, Fac Educ, POB 450,Stn A, Ottawa, ON K1N 6N5, Canada. jdsmith@uottawa.ca
AN  - WOS:000226262700006
AU  - Smith,
AU  - J.
AU  - D.
AU  - Schneider,
AU  - B.
AU  - H.
AU  - Smith,
AU  - P.
AU  - K.
AU  - Ananiadou,
AU  - K.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /1c3e/64f8a73333046bab6c0af381dec54129b86d.pdf
J2  - Sch. Psychol. Rev.
KW  - PARTICIPANT ROLE APPROACH SECONDARY-SCHOOLS INTERVENTION PERSISTENCE PREVENTION Psychology, Educational
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 886WD Times Cited: 115 Cited Reference Count: 39 Smith, JD Schneider, BH Smith, PK Ananiadou, K 116 NATL ASSN SCHOOL PSYCHOLOGISTS BETHESDA SCHOOL PSYCHOL REV
PY  - 2004
SP  - 547-560
T2  - School Psychology Review
TI  - The effectiveness of whole-school antibullying programs: A synthesis of evaluation research
UR  - &lt;Go to ISI&gt;://WOS:000226262700006
VL  - 33
ER  -
TY  - JOUR
AB  - Statistical metaanalyses on the effects of residential treatment for juvenile offenders were reviewed to examine the mean effect sizes and reductions of recidivism reported for this group. Five metaanalyses (three on North American and two on European studies) were selected and synthesized in a second-order narrative review. All metaanalyses reported positive mean effect sizes, with d statistics varying from 0.09 to 0.31, and an average reduction of recidivism by about 9%. The review showed that the &quot;nothing works&quot; hypothesis, concerning treatment effects for juvenile offenders, could be replaced by moderate optimism. However, metaanalysts need to be aware of the contextual embeddedness of treatment programs and the heterogeneity of studies included. Future research syntheses should focus on European contexts and multiple measures to evaluate long-term effects. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Grietens, Hans: hans.grietens@ped.kuleuven.ac.be Grietens, Hans: Centre for Disability, Special Needs Education and Child Care, Faculty of Psychology and Educational Sciences, U Leuven, Vesaliusstraat 2, Leuven, Belgium, B-3000, hans.grietens@ped.kuleuven.ac.be Grietens, Hans: U Leuven, Faculty of Psychology and Educational Sciences, Centre for Disability, Special Needs Education and Child Care, Leuven, Belgium Hellinckx, Walter: U Leuven, Faculty of Psychology and Educational Sciences, Centre for Disability, Special Needs Education and Child Care, Leuven, Belgium
AN  - 2004-15820-005
AU  - Grietens,
AU  - H.
AU  - Hellinckx,
AU  - W.
DA  - Jul
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/S1359-1789(03)00043-0
DP  - Ovid Technologies
KW  - juvenile offenders, residential treatment, juvenile delinquency *Group Homes *Juvenile Delinquency *Residential Care Institutions Behavior Disorders &amp; Antisocial Behavior [3230] Criminal Rehabilitation &amp; Penology [3386] Human Europe US
LA  - English
M3  - Empirical Study; Meta Analysis
PY  - 2004
SP  - 401-415
T2  - Aggression and Violent Behavior
TI  - Evaluating effects of residential treatment for juvenile offenders by statistical metaanalysis: A review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2004-15820-005
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1016%2FS1359-1789%252803%252900043-0&amp;issn=1359-1789&amp;isbn=&amp;volume=9&amp;issue=4&amp;spage=401&amp;pages=401-415&amp;date=2004&amp;title=Aggression+and+Violent+Behavior&amp;atitle=Evaluating+effects+of+residential+treatment+for+juvenile+offenders+by+statistical+metaanalysis%3A+A+review.&amp;aulast=Grietens&amp;pid=%3Cauthor%3EGrietens%2C+Hans%3C%2Fauthor%3E%3CAN%3E2004-15820-005%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S1359178903000430/1-s2.0-S1359178903000430-main.pdf?_tid=d410958c-20b0-11e5-992f-00000aab0f27&amp;acdnat=1435838134_dcef7b96bbc2eac917ebf54a82fa48c7
VL  - 9
ER  -
TY  - JOUR
AB  - This article systematically reviews the available research on rational emotive behavioral therapy (REBT) with children and adolescents. 

Meta-analytic procedures were applied to 19 studies that met inclusion criteria. The overall mean weighted effect of REBT was positive and significant. Weighted z(r) effect sizes were also computed for five outcome categories: anxiety, disruptive behaviors, irrationality, self-concept, and grade point average. In terms of magnitude, the largest positive mean effect of REBT was on disruptive behaviors. 

Analyses also revealed the following noteworthy findings: (a) there was no statistical difference between studies identified low or high in internal validity; (b) REBT appeared equally effective for children and adolescents presenting with and without identified problems; (c) non-mental health professionals produced REBT effects of greater magnitude than their mental health counterparts; (d) the longer the duration of REBT sessions, the greater the impact, and (e) children benefited more from REBT than adolescents. 

The findings are discussed in terms of several important limitations along with suggestions for future research.
AD  - Texas A&amp;M Univ, Coll Educ &amp; Human Dev, College Stn, TX 77843 USA. Gonzalez, JE (reprint author), Texas A&amp;M Univ, Coll Educ &amp; Human Dev, 4225 TAMU, College Stn, TX 77843 USA.
AN  - WOS:000225273800003
AU  - Gonzalez,
AU  - J.
AU  - E.
AU  - Nelson,
AU  - J.
AU  - R.
AU  - Gutkin,
AU  - T.
AU  - B.
AU  - Saunders,
AU  - A.
AU  - Galloway,
AU  - A.
AU  - Shwery,
AU  - C.
AU  - S
DA  - Win
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/10634266040120040301
J2  - J. Emot. Behav. Disord.
KW  - SCHOOL-PSYCHOLOGY OUTCOME RESEARCH PSYCHOTHERAPY HEALTH Education, Special Psychology, Educational Psychology, Multidisciplinary
LA  - English
M3  - Article
N1  - ISI Document Delivery No.: 873IT Times Cited: 19 Cited Reference Count: 55 Gonzalez, JE Nelson, JR Gutkin, TB Saunders, A Galloway, A Shwery, CS 20 PRO-ED INC AUSTIN J EMOT BEHAV DISORD
PY  - 2004
SP  - 222-235
T2  - Journal of Emotional and Behavioral Disorders
TI  - Rational emotive therapy with children and adolescents: A meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000225273800003http://ebx.sagepub.com/content/12/4/222http://ebx.sagepub.com/content/12/4/222.full.pdf
VL  - 12
ER  -
TY  - JOUR
AB  - The aim of this paper is to evaluate the effectiveness of brief interventions (BI) with adolescents (mean age &lt; 20) in reducing alcohol, tobacco or other drug (ATOD) use by means of a systematic review of BI for adolescent substance use in the English language literature up to 2002. 

We identified 11 studies involving 3734 adolescents. Follow-up ranged from 6 weeks to 24 months. Motivational interviewing was the predominant approach, underpinning eight studies: the remaining three provided personalized health information. Seven papers reported outcomes for alcohol interventions and four involved other substances (including one with separate alcohol outcomes). 

The overall effect size was d = 0.126 with borderline homogeneity ( Q = 14.9, df = 9, p = 0.09). The effect size from the eight alcohol interventions ( n = 1075) was classified as significant but &quot;small&quot; ( d = 0.275). The remaining non-alcohol studies were considered separately as interventions involving tobacco or multiple substance use. The two interventions with tobacco involved a substantial sample ( n = 2626) but had a very small effect ( d = 0.037), while the two interventions addressing multiple substances involved few participants ( n = 110) but had a medium - large effect ( d = 0.78). 

Across a diverse range of settings (dental clinic, schools, universities, substance treatment centres) and, therefore, probably diverse clients, BI conferred benefits to adolescent substance users. BI had a small effect on alcohol consumption and related measures. 

The data for tobacco interventions suggested a very small reduction, particularly with general community interventions. The effect of BI with multiple substances appears substantial but the small sample cautions against expansive generalization.
AD  - Univ Western Australia, Sch Psychiat &amp; Clin Neurosci, Nedlands, WA 6009, Australia. Tait, RJ (reprint author), Univ Western Australia, Sch Psychiat &amp; Clin Neurosci, QEII Campus, Nedlands, WA 6009, Australia.
AN  - WOS:000184981200011
AU  - Tait,
AU  - R.
AU  - J.
AU  - Hulse,
AU  - G.
AU  - K.
DA  - Sep
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1080/0959523031000154481
J2  - Drug Alcohol Rev.
KW  - adolescent alcohol brief intervention illicit drugs review BRIEF MOTIVATIONAL INTERVENTION COLLEGE-STUDENT DRINKERS PREVENTING ALCOHOL-USE 2-YEAR FOLLOW-UP GENERAL-PRACTICE DRINKING SMOKING CONSUMPTION PROGRAM CARE Substance Abuse
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 715PM Times Cited: 43 Cited Reference Count: 58 Tait, RJ Hulse, GK Tait, Robert/B-8693-2009 Tait, Robert/0000-0003-0648-3093 44 CARFAX PUBLISHING BASINGSTOKE DRUG ALCOHOL REV
PY  - 2003
SP  - 337-346
T2  - Drug and Alcohol Review
TI  - A systematic review of the effectiveness of brief interventions with substance using adolescents by type of drug
UR  - &lt;Go to ISI&gt;://WOS:000184981200011http://onlinelibrary.wiley.com/store/10.1080/0959523031000154481/asset/0959523031000154481.pdf?v=1&amp;t=ib7vosbc&amp;s=c5d5a29fab92f6ca8f7b472962b91f1645d56c1f
VL  - 22
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To conduct a systematic review of controlled trials for adolescent smoking cessation. 

**METHODS: **
Online bibliographic databases were searched as of June 2002, and reference lists from review articles and the selected articles were also reviewed for potential studies. The methodology and findings of all retrieved articles were critically evaluated. Data were extracted from each article regarding study methods, intervention studied, outcomes measured, and results. 

**RESULTS:** 
The abstracts or full-text articles of 281 relevant studies were examined, of which six met the selection criteria. Included were three school-based studies, a study in pregnant adolescent girls, a hospital-based study, and a trial of laser acupuncture. All three of the school-based studies reported significant impacts on cessation rates, although only one of these was a randomized trial. None of the studies had follow-up times of &gt;5.2 months. 

**CONCLUSIONS: **
There is very limited evidence demonstrating efficacy of smoking-cessation interventions in adolescents, and no evidence on the long-term effectiveness of such interventions. Smoking-cessation interventions that have proven most effective in adults, such as nicotine replacement and antidepressant use, have not been studied in adolescents in a controlled manner.
AD  - Garrison,Michelle M. Child Health Institute, University of Washington, Box 354920, 6200 NE 74th Street, Suite 210, Seattle, WA 98115, USA. garrison@u.washington.edu
AN  - 14580641
AU  - Garrison,
AU  - M.
AU  - M.
AU  - Christakis,
AU  - D.
AU  - A.
AU  - Ebel,
AU  - B.
AU  - E.
AU  - Wiehe,
AU  - S.
AU  - E.
AU  - Rivara,
AU  - F.
AU  - P.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - ikke doi
DP  - Ovid Technologies
J2  - Am J Prev Med
KW  - Adolescent Adult Child Confidence Intervals Female Humans Male Outcome Assessment (Health Care) Randomized Controlled Trials as Topic *Smoking/pc [Prevention &amp; Control]
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Garrison, Michelle M Christakis, Dimitri A Ebel, Beth E Wiehe, Sarah E Rivara, Frederick P
PY  - 2003
SP  - 363-7
T2  - American Journal of Preventive Medicine
TI  - Smoking cessation interventions for adolescents: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=14580641
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:14580641&amp;id=doi:&amp;issn=0749-3797&amp;isbn=&amp;volume=25&amp;issue=4&amp;spage=363&amp;pages=363-7&amp;date=2003&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=Smoking+cessation+interventions+for+adolescents%3A+a+systematic+review.&amp;aulast=Garrison&amp;pid=%3Cauthor%3EGarrison+MM%3C%2Fauthor%3E%3CAN%3E14580641%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0749379703002137/1-s2.0-S0749379703002137-main.pdf?_tid=ba731a28-167e-11e5-a498-00000aacb35e&amp;acdnat=1434717105_3942dc6e9fd3f048eb7b875b445676ca
VL  - 25
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Although the initial effectiveness of psychosocial strategies programming in preventing smoking and other drug abuse among adolescents has been well established through literature reviews and meta-analyses, much less evidence exists for the long-term follow-up success of these interventions. The primary goal of this paper, therefore, is to summarize the effectiveness of published program evaluation studies that have followed adolescents across the transitional period between junior high and high school for a period of at least 2 years. 

**METHODS: **
Studies for inclusion in this review were accessed primarily through a computerized search of Medline, Healthstar, and PsychINFO databases. Intervention studies that met five core criteria were retained for review. Two authors independently abstracted data on study characteristics, methodology, and program outcomes. 

**RESULTS: **
Search results yielded 25 studies suitable for examination. The majority of these studies reported significant program effects for long-term smoking, alcohol, and marijuana outcomes, while indicating a fairly consistent magnitude of program effects. 

**CONCLUSIONS: **
This review provides long-term empirical evidence of the effectiveness of social influences programs in preventing or reducing substance use for up to 15 years after completion of programming. However, this conclusion is still somewhat tenuous given the lack of significant program effects reported in several studies and the great variability that existed in the level of internal and external validity across all studies.
AD  - Skara,Silvana. Institute for Health Promotion and Disease Prevention Research, Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Alhambra, CA 91803, USA. skara@hsc.usc.edu
AN  - 14572430
AU  - Skara,
AU  - S.
AU  - Sussman,
AU  - S.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/S0091-7435(03)00166-X
DP  - Ovid Technologies
J2  - Prev Med
KW  - Adolescent *Adolescent Health Services/st [Standards] Community Health Services/st [Standards] Cross-Sectional Studies Data Interpretation, Statistical Evidence-Based Medicine Female Humans Longitudinal Studies Male Outcome Assessment (Health Care) Prog
LA  - English
M3  - Review
N1  - Skara, Silvana Sussman, Steve
PY  - 2003
SP  - 451-74
T2  - Preventive Medicine
TI  - A review of 25 long-term adolescent tobacco and other drug use prevention program evaluations
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=14572430 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:14572430&amp;id=doi:&amp;issn=0091-7435&amp;isbn=&amp;volume=37&amp;issue=5&amp;spage=451&amp;pages=451-74&amp;date=2003&amp;title=Preventive+Medicine&amp;atitle=A+review+of+25+long-term+adolescent+tobacco+and+other+drug+use+prevention+program+evaluations.&amp;aulast=Skara&amp;pid=%3Cauthor%3ESkara+S%3C%2Fauthor%3E%3CAN%3E14572430%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S009174350300166X/1-s2.0-S009174350300166X-main.pdf?_tid=a9d9036e-18ac-11e5-b919-00000aacb35e&amp;acdnat=1434956736_8e420c0996853ab4ef5ef5a5ba9c458e
VL  - 37
ER  -
TY  - JOUR
AB  - **OBJECTIVE:  **
To conduct a systematic review of randomized controlled trials of smoking prevention interventions for youth delivered via medical or dental providers&#039; offices. 

 **METHODS: **
Online bibliographic databases were searched as of July 2002, and reference lists from review articles and the selected articles were also reviewed for potential studies. The methodology and findings of all retrieved articles were critically evaluated. Data were extracted from each article regarding study methods, intervention studied, outcomes measured, and results. 

 **RESULTS: ** 
The literature search returned 81 abstracts from MEDLINE and 49 from Cochrane Clinical Trials Registry (CCTR); of these, four articles met the inclusion criteria. Included were two studies conducted in primary care, and one each in dental and orthodontic offices. Only one study demonstrated a significant effect on smoking initiation; in that study, 5.1% of the intervention group and 7.8% of the control group reported smoking at 12-month follow-up (odds ratio= 0.63; 95% confidence interval, 0.44-0.91). None of the studies had follow-up times greater than 3 years. 

 **CONCLUSIONS:  **
There is very limited available evidence demonstrating efficacy of smoking prevention interventions in adolescents conducted in providers&#039; offices and no evidence for long-term effectiveness of such interventions.
AD  - Christakis,Dimitri A. Child Health Institute, University of Washington, 6200 NE 74th Street, Suite 210, Seattle, WA 98115, USA.
AN  - 14580640
AU  - Christakis,
AU  - D.
AU  - A.
AU  - Garrison,
AU  - M.
AU  - M.
AU  - Ebel,
AU  - B.
AU  - E.
AU  - Wiehe,
AU  - S.
AU  - E.
AU  - Rivara,
AU  - F.
AU  - P.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/s0749-3797(03)00214-9
DP  - Ovid Technologies
J2  - Am J Prev Med
KW  - Adult Child Health Personnel Humans Randomized Controlled Trials as Topic *Smoking/pc [Prevention &amp; Control]
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Christakis, Dimitri A Garrison, Michelle M Ebel, Beth E Wiehe, Sarah E Rivara, Frederick P
PY  - 2003
SP  - 358-62
T2  - American Journal of Preventive Medicine
TI  - Pediatric smoking prevention interventions delivered by care providers: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=14580640
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:14580640&amp;id=doi:&amp;issn=0749-3797&amp;isbn=&amp;volume=25&amp;issue=4&amp;spage=358&amp;pages=358-62&amp;date=2003&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=Pediatric+smoking+prevention+interventions+delivered+by+care+providers%3A+a+systematic+review.&amp;aulast=Christakis&amp;pid=%3Cauthor%3EChristakis+DA%3C%2Fauthor%3E%3CAN%3E14580640%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0749379703002149/1-s2.0-S0749379703002149-main.pdf?_tid=aae8b496-167e-11e5-a6bb-00000aacb35e&amp;acdnat=1434717079_43c4514753bc06e9c212a81b8fa5d007
VL  - 25
ER  -
TY  - JOUR
AB  - BACKGROUND: Worldwide, 340 million people are affected by depression, with high comorbid, social and economic costs.AIMS: To identify potential predictors of effect in prevention programmes.METHOD: A meta-analysis was made of 69 programmes to reduce depression or depressive symptoms.RESULTS: The weighted mean effect size of 0.22 was effective for different age groups and different levels of risk, and in reducing risk factors and depressive or psychiatric symptoms. Programmes with larger effect sizes were multi-component, included competence techniques, had more than eight sessions, had sessions 60-90 min long, had a high quality of research design and were delivered by a health care provider in targeted programmes. Older people benefited from social support, whereas behavioural methods were detrimental.CONCLUSIONS: An 11% improvement in depressive symptoms can be achieved through prevention programmes. Single trial evaluations should ensure high quality of the research design and detailed reporting of results and potential predictors. [References: 84]
AD  - Jane-Llopis, Eva. Prevention Research Centre, Department of Clinical Psychology and Personality, Nijmegen University, The Netherlands. llopis@psych.kun.nl
AN  - 14594912
AU  - DUBLETT_Jane-Llopis,
AU  - E.
AU  - Hosman,
AU  - C.
AU  - Jenkins,
AU  - R.
AU  - Anderson,
AU  - P.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
DP  - Ovid Technologies
J2  - Br J Psychiatry
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Child
KW  - Cognitive Therapy/mt [Methods]
KW  - *Depressive Disorder/pc [Prevention &amp; Control]
KW  - Female
KW  - Humans
KW  - Male
KW  - Mental Competency
KW  - Middle Aged
KW  - Randomized Controlled Trials as Topic
KW  - Social Support
KW  - *Treatment Outcome
L1  - internal-pdf://4162849971/Jane-Llopis-2003-Predictors of efficacy in dep.pdf
LA  - English
M3  - Meta-AnalysisResearch Support, Non-U.S. Gov&#039;tReview
N1  - Jane-Llopis, EvaHosman, ClemensJenkins, RachelAnderson, PeterComment in: Br J Psychiatry. 2004 Mar;184:272; PMID: 14990532Comment in: Evid Based Ment Health. 2004 May;7(2):44; PMID: 15107340
PY  - 2003
SP  - 384-97
T2  - British Journal of Psychiatry
TI  - Predictors of efficacy in depression prevention programmes. Meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=14594912
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:14594912&amp;id=doi:&amp;issn=0007-1250&amp;isbn=&amp;volume=183&amp;issue=&amp;spage=384&amp;pages=384-97&amp;date=2003&amp;title=British+Journal+of+Psychiatry&amp;atitle=Predictors+of+efficacy+in+depression+prevention+programmes.+Meta-analysis.&amp;aulast=Jane-Llopis&amp;pid=%3Cauthor%3EJane-Llopis+E%3C%2Fauthor%3E%3CAN%3E14594912%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0EE8EB28B4909638F813EACEF3FA6E2A/S0007125000028154a.pdf/div-class-title-predictors-of-efficacy-in-depression-prevention-programmes-div.pdf
VL  - 183
ER  -
TY  - JOUR
AB  - The inadequate supply of affordable housing for low-income families and the increasing spatial segregation of some households by income, race, ethnicity, or social class into unsafe neighborhoods are among the most prevalent community health concerns related to family housing. 

When affordable housing is not available to low-income households, family resources needed for food, medical or dental care, and other necessities are diverted to housing costs. Two housing programs intended to provide affordable housing and, concurrently, reduce the residential segregation of low-income families into unsafe neighborhoods of concentrated poverty, are reviewed: the creation of mixed-income housing developments and the Department of Housing and Urban Development (HUD) Section 8 Rental Voucher Program. 

The effectiveness of mixed-income housing developments could not be ascertained by this systematic review because of a lack of comparative research. Scientific evidence was sufficient to conclude that rental voucher programs improve household safety as measured by reduced exposure to crimes against person and property and decreased neighborhood social disorder. 

Effectiveness of rental voucher programs on youth health risk behaviors, mental health status, and physical health status could not be determined because too few studies of adequate design and execution reported these outcomes.
AD  - Anderson,Laurie M. Division of Prevention Research and Analytic Methods, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. LAA1@cdc.gov
AN  - 12668198
AU  - Anderson,
AU  - L.
AU  - M.
AU  - Charles,
AU  - J.
AU  - S.
AU  - Fullilove,
AU  - M.
AU  - T.
AU  - Scrimshaw,
AU  - S.
AU  - C.
AU  - Fielding,
AU  - J.
AU  - E.
AU  - Normand,
AU  - J.
AU  - Task
AU  - Force
AU  - on
AU  - Community
AU  - Preventive
AU  - Services
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/S0749-3797(02)00656-6
DP  - Ovid Technologies
J2  - Am J Prev Med
KW  - Family/px [Psychology] *Health Promotion Housing/ec [Economics] Housing/sn [Statistics &amp; Numerical Data] *Housing Humans *Income *Prejudice United States Urban Population
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Anderson, Laurie M Charles, Joseph St Fullilove, Mindy T Scrimshaw, Susan C Fielding, Jonathan E Normand, Jacques Task Force on Community Preventive Services Comment in: Am J Prev Med. 2003 Apr;24(3 Suppl):2-3; PMID: 12668189
PY  - 2003
SP  - 47-67
T2  - American Journal of Preventive Medicine
TI  - Providing affordable family housing and reducing residential segregation by income. A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=12668198
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:12668198&amp;id=doi:&amp;issn=0749-3797&amp;isbn=&amp;volume=24&amp;issue=3&amp;spage=47&amp;pages=47-67&amp;date=2003&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=Providing+affordable+family+housing+and+reducing+residential+segregation+by+income.+A+systematic+review.&amp;aulast=Anderson&amp;pid=%3Cauthor%3EAnderson+LM%3C%2Fauthor%3E%3CAN%3E12668198%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0749379702006566/1-s2.0-S0749379702006566-main.pdf?_tid=94d63fde-167e-11e5-b7f6-00000aacb360&amp;acdnat=1434717042_7dde2d6c6c1fcc84eaf69e782d2a86ab
VL  - 24
ER  -
TY  - JOUR
AB  - The objectives of this research were to determine the effectiveness of preschool prevention programs for disadvantaged children and families in the short-term (preschool), medium-term (kindergarten-8th grade), and the long-term (high school and beyond) and to identify factors that moderate program success. 

Meta-analysis was used to examine the effect sizes (d) of different outcome domains of 34 preschool prevention programs that had at least one follow-up assessment when the children were in school. Although cognitive impacts resulting from these programs were greatest during the preschool period (d=0.52), they were still evident during kindergarten through Grade 8 (K-8; d=0.30). Social-emotional impacts on children were similar at K-8 (d=0.27) and high school and beyond (d=0.33), as were parent-family wellness impacts at preschool (d=0.33) and K-8 (d=0.30). 

As predicted, cognitive impacts during the preschool time period were greatest for those programs that had a direct teaching component in preschool. Also as predicted, cognitive impacts during the K-8 time period were greatest for those programs that had a follow-through educational component in elementary school... (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Nelson, Geoffrey: gnelson@wlu.ca Nelson, Geoffrey: Department of Psychology, Wilfrid Laurier University, Waterloo, ON, N2L 3C5, gnelson@wlu.ca Nelson, Geoffrey: Wilfrid Laurier University, Waterloo, ON, Canada Westhues, Anne: Wilfrid Laurier University, Waterloo, ON, Canada MacLeod, Jennifer: Wellington-Dufferin-Guelph Health Unit, Fergus, ON, Canada
AN  - 2003-11113-001
AU  - Nelson,
AU  - G.
AU  - Westhues,
AU  - A.
AU  - MacLeod,
AU  - J.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/1522-3736.6.1.631a
DP  - Ovid Technologies
KW  - preschool prevention programs, effectiveness, disadvantaged children, cognitive development, socio-emotional behavior, parent-family wellness, families, educational program *Cognitive Development *Disadvantaged *Preschool Education *Prevention *Treatmen
LA  - English
M3  - Meta Analysis
PY  - 2003
SP  - No Pagination Specified
T2  - Prevention &amp; Treatment
TI  - A Meta-Analysis of Longitudinal Research on Preschool Prevention Programs for Children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2003-11113-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1037%2F1522-3736.6.1.631a&amp;issn=1522-3736&amp;isbn=&amp;volume=6&amp;issue=1&amp;spage=No&amp;pages=No+Pagination+Specified&amp;date=2003&amp;title=Prevention+%26+Treatment&amp;atitle=A+Meta-Analysis+of+Longitudinal+Research+on+Preschool+Prevention+Programs+for+Children.&amp;aulast=Nelson&amp;pid=%3Cauthor%3ENelson%2C+Geoffrey%3C%2Fauthor%3E%3CAN%3E2003-11113-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://psycnet.apa.org/journals/pre/6/1/31a.pdf
VL  - 6
ER  -
TY  - JOUR
AB  - Is early preventive intervention effective in enhancing parental sensitivity and infant attachment security, and if so, what type of intervention is most successful? 

Seventy studies were traced, producing 88 intervention effects on sensitivity (n = 7,636) and/or attachment (n = 1,503). Randomized interventions appeared rather effective in changing insensitive parenting (d = 0.33) and infant attachment insecurity (d = 0.20). 

The most effective interventions used a moderate number of sessions and a clear-cut behavioral focus in families with, as well as without, multiple problems. Interventions that were more effective in enhancing parental sensitivity were also more effective in enhancing attachment security, which supports the notion of a causal role of sensitivity in shaping attachment.
AD  - Bakermans-Kranenburg,Marian J. Center for Child and Family Studies, Leiden University, The Netherlands.
AN  - 12696839
AU  - Bakermans-Kranenburg,
AU  - M.
AU  - J.
AU  - Jzendoorn
AU  - M.
AU  - H.
AU  - van,
AU  - I.
AU  - Juffer,
AU  - F.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/0033-2909.129.2.195
DP  - Ovid Technologies
J2  - Psychol Bull
KW  - *Behavior Therapy Cross-Sectional Studies *Family Therapy Follow-Up Studies Humans Infant *Object Attachment Outcome and Process Assessment (Health Care) *Parenting/px [Psychology] Personality Assessment Randomized Controlled Trials as Topic
LA  - English
M3  - Comparative Study Meta-Analysis
N1  - Bakermans-Kranenburg, Marian J van IJzendoorn, Marinus H Juffer, Femmie
PY  - 2003
SP  - 195-215
T2  - Psychological Bulletin
TI  - Less is more: meta-analyses of sensitivity and attachment interventions in early childhood
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=12696839 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:12696839&amp;id=doi:&amp;issn=0033-2909&amp;isbn=&amp;volume=129&amp;issue=2&amp;spage=195&amp;pages=195-215&amp;date=2003&amp;title=Psychological+Bulletin&amp;atitle=Less+is+more%3A+meta-analyses+of+sensitivity+and+attachment+interventions+in+early+childhood.&amp;aulast=Bakermans-Kranenburg&amp;pid=%3Cauthor%3EBakermans-Kranenburg+MJ%3C%2Fauthor%3E%3CAN%3E12696839%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://psycnet.apa.org/journals/bul/129/2/195.pdf
VL  - 129
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
The authors conducted a meta-analysis of published randomized, controlled medication trials in children and adolescents with obsessive-compulsive disorder (OCD) to assess evidence for differential efficacy based on type of drug, study design, and outcome measure. 

**METHOD: **
A systematic literature search was performed for articles pertaining to the pharmacological treatment of pediatric and/or adolescent OCD. All baseline, posttreatment, and change scores with standard deviations reported in each study were included in the analyses. Effect sizes for dependent measures were expressed as standardized mean differences. The analysis included data on efficacy for four selective serotonin reuptake inhibitors (SSRIs) (paroxetine, fluoxetine, fluvoxamine, and sertraline) and clomipramine, four study designs, four dependent outcome measures, and two types of outcome scores (change and posttreatment scores). Multivariate regression was performed to assess the degree to which the effect sizes varied with the methodological features of each study.

**RESULTS: **
Twelve studies with a total of 1,044 participants met all inclusion criteria for the analysis. The pooled standardized mean difference for the results of all studies was 0.46 and showed a highly significant difference between drug and placebo treatment. Only one of the four outcome measures evaluated was not sensitive to change with treatment. A multivariate regression analysis of drug effect with other variables controlled showed that clomipramine was significantly superior to each of the SSRIs but that the SSRIs were comparably effective. 

**CONCLUSIONS:**
Although highly significant, the overall effect sizes for medication were modest. Similarities and differences between the variables studied that emerged in the meta-analysis may have implications for both clinical care and future research.
AD  - Geller,Daniel A. Pediatric OCD Problem, WACC 725, Massachusetts General Hospital, 15 Parkman Street, Boston, MA 02114, USA. dageller@partners.org
AN  - 14594734
AU  - Geller,
AU  - D.
AU  - A.
AU  - Biederman,
AU  - J.
AU  - Stewart,
AU  - S.
AU  - E.
AU  - Mullin,
AU  - B.
AU  - Martin,
AU  - A.
AU  - Spencer,
AU  - T.
AU  - Faraone,
AU  - S.
AU  - V.
DA  - Nov
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1176/appi.ajp.160.11.1919
DP  - Ovid Technologies
J2  - Am J Psychiatry
KW  - Adolescent Age Factors Child Clomipramine/tu [Therapeutic Use] Humans Obsessive-Compulsive Disorder/di [Diagnosis] *Obsessive-Compulsive Disorder/dt [Drug Therapy] Obsessive-Compulsive Disorder/px [Psychology] Personality Inventory Placebos Psychiatric
LA  - English
M3  - Comparative Study Meta-Analysis Research Support, Non-U.S. Gov&#039;t Research Support, U.S. Gov&#039;t, P.H.S.
N1  - Geller, Daniel A Biederman, Joseph Stewart, S Evelyn Mullin, Benjamin Martin, Andres Spencer, Thomas Faraone, Stephen V Comment in: Evid Based Ment Health. 2004 May;7(2):50; PMID: 15107346 MH 01481 (United States NIMH NIH HHS) MH 01792 (United States NIMH NIH HHS)
PY  - 2003
SP  - 1919-28
T2  - American Journal of Psychiatry
TI  - Which SSRI? A meta-analysis of pharmacotherapy trials in pediatric obsessive-compulsive disorder
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=14594734
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:14594734&amp;id=doi:&amp;issn=0002-953X&amp;isbn=&amp;volume=160&amp;issue=11&amp;spage=1919&amp;pages=1919-28&amp;date=2003&amp;title=American+Journal+of+Psychiatry&amp;atitle=Which+SSRI%3F+A+meta-analysis+of+pharmacotherapy+trials+in+pediatric+obsessive-compulsive+disorder.&amp;aulast=Geller&amp;pid=%3Cauthor%3EGeller+DA%3C%2Fauthor%3E%3CAN%3E14594734%3C%2FAN%3E%3CDT%3EComparative+Study%3C%2FDT%3Ehttp://media.proquest.com/media/pq/classic/doc/499236381/fmt/pi/rep/NONE?hl=&amp;cit%3Aauth=Geller%2C+Daniel+A%3BBiederman%2C+Joseph%3BStewart%2C+S+Evelyn%3BMullin%2C+Benjamin%3Bet+al&amp;cit%3Atitle=Which+SSRI%3F+A+Meta-Analysis+of+Pharmacotherapy+Trials+in+Pediatric+Obsessive-Compulsive+Disorder&amp;cit%3Apub=The+American+Journal+of+Psychiatry&amp;cit%3Avol=160&amp;cit%3Aiss=11&amp;cit%3Apg=1919&amp;cit%3Adate=Nov+2003&amp;ic=true&amp;cit%3Aprod=ProQuest&amp;_a=ChgyMDE1MDYxOTEwMzYyOTY3Njo2NjQ1NzgSBTc5MDkxGgpPTkVfU0VBUkNIIgs4Ni42Mi4xODAuNioFNDA2NjEyCTIyMDQ4MjA3NDoNRG9jdW1lbnRJbWFnZUIBMFIGT25saW5lWgJGVGIDUEZUagoyMDAzLzExLzAxcgoyMDAzLzExLzMwegCCASlQLTEwMDAyNzMtMzEwNzUtQ1VTVE9NRVItMTAwMDAxNTctMTExNTExMpIBBk9ubGluZcoBB0VuZE5vdGXSARJTY2hvbGFybHkgSm91cm5hbHOaAgdQcmVQYWlkqgIoT1M6RU1TLVBkZkRvY1ZpZXdCYXNlLWdldE1lZGlhVXJsRm9ySXRlbcoCD0ZlYXR1cmV8QXJ0aWNsZdICAVniAgFO8gIA&amp;_s=UN4eoJpaLg1Zxvvyaq3fpEpyAEU%3D
VL  - 160
ER  -
TY  - JOUR
AB  - Determined the effect size for nonstimulant medications on symptoms of overt aggression-related behaviors in referred children and adolescents with serious emotional and behavioral disturbances. 

A review of the literature between 1970 and 2001 revealed 33 studies meeting exclusion/inclusion criteria and yielding 37 independent effects for neuroleptic, atypical antipsychotic, mood stabilizer, antidepressant, and adrenergic agents on symptoms of overt aggression. Group 1 received medications for severely ill children (neuroleptics, mood stabilizers, etc...), while Group 2 received medications for less severely ill children (antidepressants). Overall weighted mean effect sizes were moderate to large for overt aggression within a heterogeneous group of psychiatric disorders. Moderators of effect size included drug group, study design, and the interaction between drug group and study design. 

The results support common clinical practice of including medications as part of a comprehensive psychoeducational treatment plan for some youth with maladaptive overt aggression within a variety of psychiatric disorders; however, not all referred youth respond to medication for overt aggression-related behavior, supporting the use of additional nonmedication interventions. (PsycINFO Database Record (c) 2012 APA, all rights reserved).
AD  - Thomas Connor, Daniel F.: daniel.connor@umassmed.edu Connor, Daniel F.: Dept of Psychiatry, 7th Floor, Room S7-802, U Massachusetts, 55 Lake Avenue, North Worcester, MA, US, 01655, daniel.connor@umassmed.edu Connor, Daniel F.: U Massachusetts Medical School, Div of Child &amp; Adolescent Psychiatry, North Worcester, MA, US Boone, R. Thomas: St John&#039;s U, Jamaica, NY, US Steingard, Ronald J.: U Massachusetts Medical School, Div of Child &amp; Adolescent Psychiatry, North Worcester, MA, US Lopez, Ivan D.: U Massachusetts Medical School, North Worcester, MA, US Melloni, Richard H.: Northeastern U, Dept of Psychology, North Worcester, MA, US
AN  - 2003-07877-003
AU  - Connor,
AU  - D.
AU  - F.
AU  - Boone,
AU  - T.
AU  - Steingard,
AU  - R.
AU  - J.
AU  - Lopez,
AU  - I.
AU  - D.
AU  - Melloni,
AU  - R.
AU  - H.
DA  - Fal
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1177/10634266030110030301
DP  - Ovid Technologies
KW  - overt aggression, psychiatric disorders, children, non-stimulant medications, antidepressants, effect size *Aggressive Behavior *Child Psychiatry *Drug Therapy *Effect Size (Statistical) *Mental Disorders Clinical Psychopharmacology [3340] Human Childho
LA  - English
M3  - Meta Analysis
PY  - 2003
SP  - 157-168
T2  - Journal of Emotional and Behavioral Disorders
TI  - Psychopharmacology and Aggression: II. A meta-analysis of nonstimulant medication effects on overt aggression-related behaviors in youth with SED
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2003-07877-003
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1177%2F10634266030110030301&amp;issn=1063-4266&amp;isbn=&amp;volume=11&amp;issue=3&amp;spage=157&amp;pages=157-168&amp;date=2003&amp;title=Journal+of+Emotional+and+Behavioral+Disorders&amp;atitle=Psychopharmacology+and+Aggression%3A+II.+A+meta-analysis+of+nonstimulant+medication+effects+on+overt+aggression-related+behaviors+in+youth+with+SED.&amp;aulast=Connor&amp;pid=%3Cauthor%3EConnor%2C+Daniel+F%3C%2Fauthor%3E%3CAN%3E2003-07877-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ebx.sagepub.com/content/11/3/157http://ebx.sagepub.com/content/11/3/157.full.pdf
VL  - 11
ER  -
TY  - JOUR
AB  - There is evidence from a range of studies showing adverse child outcomes for the children of teenage parents. Parenting programmes are increasingly being used to promote the well-being of parents and children, and this review aims to establish whether they can improve outcomes for teenage parents and their children. 

The findings of the review are based on 14 studies that used varying study designs, and are therefore limited. 
The results suggest, however, that parenting programmes can be effective in improving a range of psychosocial and developmental outcomes for teenage mothers and their children. Further research is needed. 

(C) 2002 The Association for Professionals in Services for Adolescents. Published by Elsevier Science Ltd. All rights reserved.
AD  - Univ Oxford, Inst Hlth Sci, Hlth Serv Res Unit, Oxford OX3 7LF, England. UK Cochrane Ctr, Oxford OX2 7LG, England. Barlow, J (reprint author), Univ Oxford, Inst Hlth Sci, Hlth Serv Res Unit, Old Rd, Oxford OX3 7LF, England.
AN  - WOS:000181093400006
AU  - Coren,
AU  - E.
AU  - Barlow,
AU  - J.
AU  - Stewart-Brown,
AU  - S.
DA  - Feb
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/s0140-1971(02)00119-7
J2  - J. Adolesc.
KW  - ADOLESCENT MOTHERS SELF-ESTEEM RISK BEHAVIOR RANDOMIZATION INTERVENTION VIDEOTAPE ATTITUDES KNOWLEDGE INFANTS Psychology, Developmental
LA  - English
M3  - Review
N1  - ISI Document Delivery No.: 647LC Times Cited: 32 Cited Reference Count: 51 Coren, E Barlow, J Stewart-Brown, S 32 ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD LONDON J ADOLESCENCE
PY  - 2003
SP  - 79-103
T2  - Journal of Adolescence
TI  - The effectiveness of individual and group-based parenting programmes in improving outcomes for teenage mothers and their children: a systematic review
UR  - &lt;Go to ISI&gt;://WOS:000181093400006http://ac.els-cdn.com/S0140197102001197/1-s2.0-S0140197102001197-main.pdf?_tid=682ef3b4-165a-11e5-ab5a-00000aacb361&amp;acdnat=1434701505_39e0a3d23a9a73d1d75703c12354278e
VL  - 26
ER  -
TY  - JOUR
AB  - Early childhood development is influenced by characteristics of the child, the family, and the broader social environment. Physical health, cognition, language, and social and emotional development underpin school readiness. 

Publicly funded, center-based, comprehensive early childhood development programs are a community resource that promotes the well-being of young children. 

Programs such as Head Start are designed to close the gap in readiness to learn between poor children and their more economically advantaged peers. 

Systematic reviews of the scientific literature demonstrate effectiveness of these programs in preventing developmental delay, as assessed by reductions in retention in grade and placement in special education.
AD  - Anderson,Laurie M. Division of Prevention Research and Analytic Methods, Epidemiology Program Office, Centers for Disease Control and Prevention (Anderson, Shinn, Carande-Kulis), Atlanta, Georgia 30341, USA. LAA1@cdc.gov
AN  - 12668197
AU  - Anderson,
AU  - L.
AU  - M.
AU  - Shinn,
AU  - C.
AU  - Fullilove,
AU  - M.
AU  - T.
AU  - Scrimshaw,
AU  - S.
AU  - C.
AU  - Fielding,
AU  - J.
AU  - E.
AU  - Normand,
AU  - J.
AU  - Carande-Kulis,
AU  - V.
AU  - G.
AU  - Task
AU  - Force
AU  - on
AU  - Community
AU  - Preventive
AU  - Services
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/S0749-3797(02)00655-4
DP  - Ovid Technologies
J2  - Am J Prev Med
KW  - Child Child Development Cognition *Community Health Services *Early Intervention (Education) *Health Promotion Humans Poverty
LA  - English
M3  - Research Support, Non-U.S. Gov&#039;t Review
N1  - Anderson, Laurie M Shinn, Carolynne Fullilove, Mindy T Scrimshaw, Susan C Fielding, Jonathan E Normand, Jacques Carande-Kulis, Vilma G Task Force on Community Preventive Services Comment in: Am J Prev Med. 2003 Apr;24(3 Suppl):2-3; PMID: 12668189 Comment in: Am J Prev Med. 2003 Apr;24(3 Suppl):4-5; PMID: 12668190
PY  - 2003
SP  - 32-46
T2  - American Journal of Preventive Medicine
TI  - The effectiveness of early childhood development programs. A systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=12668197
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:12668197&amp;id=doi:&amp;issn=0749-3797&amp;isbn=&amp;volume=24&amp;issue=3&amp;spage=32&amp;pages=32-46&amp;date=2003&amp;title=American+Journal+of+Preventive+Medicine&amp;atitle=The+effectiveness+of+early+childhood+development+programs.+A+systematic+review.&amp;aulast=Anderson&amp;pid=%3Cauthor%3EAnderson+LM%3C%2Fauthor%3E%3CAN%3E12668197%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0749379702006554/1-s2.0-S0749379702006554-main.pdf?_tid=9b476424-167e-11e5-b8dc-00000aab0f27&amp;acdnat=1434717053_9ee9fa8843f83b4846e0bfcf4b98d021
VL  - 24
ER  -
TY  - JOUR
AB  - This article reviews controlled research on treatments for childhood externalizing behavior disorders. 

The review is organized around 2 subsets of such disorders: disruptive behavior disorders (i.e., conduct disorder, oppositional defiant disorder) and attention-deficit/hyperactivity disorder (ADHD). 

The review was based on a literature review of nonresidential treatments for youths ages 6-12. 

The pool of studies for this age group was limited, but results suggest positive outcomes for a variety of interventions (particularly parent training and community-based interventions for disruptive behavior disorders and medication for ADHD). 

The review also highlights the need for additional research examining effectiveness of treatments for this age range and strategies to enhance the implementation of effective practices.
AD  - Farmer,Elizabeth M Z. Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina 27710-3454, USA. bfarmer@psych.mc.duke.edu
AN  - 12472301
AU  - Farmer,
AU  - E.
AU  - M.
AU  - Compton,
AU  - S.
AU  - N.
AU  - Bums,
AU  - B.
AU  - J.
AU  - Robertson,
AU  - E.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/0022-006X.70.6.1267
DP  - Ovid Technologies
J2  - J Consult Clin Psychol
KW  - Adolescent Antisocial Personality Disorder/di [Diagnosis] Antisocial Personality Disorder/px [Psychology] Antisocial Personality Disorder/th [Therapy] Attention Deficit Disorder with Hyperactivity/di [Diagnosis] Attention Deficit Disorder with Hyperacti
LA  - English
M3  - Research Support, U.S. Gov&#039;t, P.H.S. Review
N1  - Farmer, Elizabeth M Z Compton, Scott N Bums, Barbara J Robertson, Elizabeth Comment in: Evid Based Ment Health. 2003 Aug;6(3):81; PMID: 12893792 263-MJ-919512 (United States PHS HHS)
PY  - 2002
SP  - 1267-302
T2  - Journal of Consulting and Clinical Psychology
TI  - Review of the evidence base for treatment of childhood psychopathology: externalizing disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=12472301 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:12472301&amp;id=doi:&amp;issn=0022-006X&amp;isbn=&amp;volume=70&amp;issue=6&amp;spage=1267&amp;pages=1267-302&amp;date=2002&amp;title=Journal+of+Consulting+%26+Clinical+Psychology&amp;atitle=Review+of+the+evidence+base+for+treatment+of+childhood+psychopathology%3A+externalizing+disorders.&amp;aulast=Farmer&amp;pid=%3Cauthor%3EFarmer+EM%3C%2Fauthor%3E%3CAN%3E12472301%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://psycnet.apa.org/journals/ccp/70/6/1267.pdf
VL  - 70
ER  -
TY  - JOUR
AB  - A systematic review and subset meta-analysis of published randomised controlled trials of psychological therapies for children and adolescents with chronic pain is reported. A search of four computerised abstracting services recovered 123 papers from which 28 potential trials were identified. Eighteen met the criteria for inclusion in the review. The majority of these papers reported brief behavioural and cognitive behavioural interventions for children with headache and many were conducted in community (i.e. school) settings. Meta-analysis was applicable for 12 headache trials and one trial of recurrent abdominal pain using the Pain Index. The odds-ratio for a 50% reduction in pain was 9.62 and the number needed to treat was 2.32, indicating that the psychological treatments examined are effective in reducing the pain of headache. The quality of the 18 trials retrieved is narratively reviewed and suggestions for the development of trials in this field are made.
AD  - Eccleston, Christopher. Pain Management Unit, University of Bath, UK. c.eccleston@bath.ac.uk
AN  - 12237193
AU  - Eccleston,
AU  - C.
AU  - Morley,
AU  - S.
AU  - Williams,
AU  - A.
AU  - Yorke,
AU  - L.
AU  - Mastroyannopoulou,
AU  - K.
DA  - Sep
DB  - Rekoding IN SUM_lme.enl
DO  - 0.1016/s0304-3959(02)00072-6
DP  - Ovid Technologies
J2  - Pain
KW  - Abdominal Pain/px [Psychology]
KW  - Abdominal Pain/th [Therapy]
KW  - Adolescent
KW  - Child
KW  - Chronic Disease
KW  - *Headache/px [Psychology]
KW  - *Headache/th [Therapy]
KW  - Humans
KW  - *Psychotherapy
KW  - Randomized Controlled Trials as Topic
L1  - internal-pdf://3031164995/Eccleston-2002.pdf
LA  - English
M3  - Meta-Analysis
Systematic Review
N1  - Eccleston, ChristopherMorley, StephenWilliams, AmandaYorke, LouiseMastroyannopoulou, KikiComment in (CIN)
PY  - 2002
SP  - 157-65
T2  - Pain
TI  - Systematic review of randomised controlled trials of psychological therapy for chronic pain in children and adolescents, with a subset meta-analysis of pain relief
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=12237193
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:12237193&amp;id=doi:10.1016%2Fs0304-3959%2802%2900072-6&amp;issn=0304-3959&amp;isbn=&amp;volume=99&amp;issue=1-2&amp;spage=157&amp;pages=157-65&amp;date=2002&amp;title=Pain&amp;atitle=Systematic+review+of+randomised+controlled+trials+of+psychological+therapy+for+chronic+pain+in+children+and+adolescents%2C+with+a+subset+meta-analysis+of+pain+relief.&amp;aulast=Eccleston&amp;pid=%3Cauthor%3EEccleston+C%3C%2Fauthor%3E%3CAN%3E12237193%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
UR  - https://www.sciencedirect.com/science/article/pii/S0304395902000726?via%3Dihub
VL  - 99
ER  -
TY  - JOUR
AB  - **PURPOSE: **
To determine whether developmental care interventions reduce neurodevelopmental delay, poor weight gain, length of hospital stay, length of mechanical ventilation, physiologic stress, and other clinically relevant adverse outcomes in preterm infants. 

**SUBJECTS: **
Infants born at less than 37 weeks postconceptional age. This review consisted of 31 studies in 4 categories of developmental care interventions, 19 subgroups, and multiple clinical outcomes. The total sample sizes in the individual studies ranged from 16 to 259; the sample size in 18 of the studies was less than 50. 

**DESIGN AND METHODS: **
A systematic review, based on the Cochrane Collaboration format, of all randomized trials in which elements of developmental care are compared with routine nursery care and that measured clinically relevant outcomes. Searches were made of MEDLINE from 1966 to July 2000. Additional databases were also searched electronically. Reference lists and bibliographies of relevant articles were hand-searched. Experts in the field were contracted. If more than one study in an outcome category existed, a meta-analysis was conducted. 

**PRIMARY OUTCOME MEASURES: **
Outcome measures included the following: length of hospital stay, weight at discharge, neurodevelopment, physiologic parameters, feeding growth, sleep/wake states, age at discharge, neonatal outcomes, cost of hospital stay, and death. 

**PRINCIPAL RESULTS: **
Developmental care interventions showed some benefit to preterm infants with respect to improved short-term growth outcomes, decreased respiratory support, decreased incidence of moderate to severe chronic lung disease, decreased length and cost of hospital stay, and improved neurodevelopmental outcomes to 24 months corrected age. These findings were based on 2 or 3 small trials for each outcome. Although a number of other benefits were shown, those results were from single studies with small sample sizes. The lack of blinding of the assessors of the outcome variables was a significant methodological flaw in half of the studies. The costs of the interventions and personnel were not considered in any of the studies. 

**CONCLUSIONS:**
In most studies, the inclusion of multiple interventions made the determination of the effect of any single intervention difficult. Although there is evidence of some benefit of developmental care interventions overall and no major harmful effects reported, there were a large number of outcomes for which no or conflicting effects were shown. The single trials that did show a significant effect of an intervention on a major clinical outcome were based on small sample sizes, and the findings often were not supported in other small trials. Before a clear direction for practice can be supported, evidence showing more consistent effects of developmental care interventions on important short- and long-term clinical outcomes is needed. The economic impact of the implementation and maintenance of developmental care practices should be considered by individual institutions.
AD  - Symington,Amanda. Children&#039;s Hospital, Hamilton Health Sciences Corporation, 4A Neo, 1200 Main St West, Hamilton, ON, Canada L8N 3Z5. symington@hhsc.ca
AN  - 12881934
AU  - Symington,
AU  - A.
AU  - Pinelli,
AU  - J.
AU  - M.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pubmed/12881934
DP  - Ovid Technologies
J2  - Adv Neonat Care
KW  - Birth Weight Child Development/ph [Physiology] *Developmental Disabilities/nu [Nursing] *Developmental Disabilities/pc [Prevention &amp; Control] Female Follow-Up Studies Humans *Infant Care/st [Standards] Infant Care/td [Trends] Infant, Newborn *Infant, Pr
LA  - English
M3  - Review
N1  - Symington, Amanda Pinelli, Janet M
PY  - 2002
SP  - 198-221
T2  - Advances in Neonatal Care
TI  - Distilling the evidence on developmental care: a systematic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=12881934
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:12881934&amp;id=doi:&amp;issn=1536-0903&amp;isbn=&amp;volume=2&amp;issue=4&amp;spage=198&amp;pages=198-221&amp;date=2002&amp;title=Advances+in+Neonatal+Care&amp;atitle=Distilling+the+evidence+on+developmental+care%3A+a+systematic+review.&amp;aulast=Symington&amp;pid=%3Cauthor%3ESymington+A%3C%2Fauthor%3E%3CAN%3E12881934%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3E
VL  - 2
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To quantify the effectiveness of school-based violence prevention programs for children identified as at risk for aggressive behavior. 

**DESIGN: **
Systematic review and meta-analysis of randomized controlled trials. Electronic databases and bibliographies were systematically searched and authors and organizations were contacted to identify randomized controlled trials. Standardized, weighted mean effect sizes were assessed by meta-analysis. 

**SETTING: **
Elementary, middle, and high schools. 

**PARTICIPANTS: **
Children at risk for aggressive behavior. 

**MAIN OUTCOME MEASURES: **
Violent injuries, observed or reported aggressive or violent behaviors, and school or agency responses to aggressive behaviors. 

**RESULTS: **
Of the 44 trials identified, none reported data on violent injuries. For the 28 trials that assessed aggressive behaviors, the pooled difference between study groups was -0.36 (95% confidence interval, -0.54 to -0.19) in favor of a reduction in aggression with intervention. For the 9 trials that reported data on school or agency responses to aggression, the pooled difference was -0.59 (95% confidence interval, -1.18 to 0.01). Subgroup analyses suggested greater effectiveness in older students and when administered to mixed-sex groups rather than to boys alone. 

**CONCLUSIONS:** 
School-based violence prevention programs may produce reductions in aggressive and violent behaviors in children who already exhibit such behavior. These results, however, need to be confirmed in large, high-quality trials.
AD  - Mytton,Julie A. Department of Paediatric Epidemiology and Biostatistics, London, England. jmytton@doctors.org.uk
AN  - 12144364
AU  - Mytton,
AU  - J.
AU  - A.
AU  - DiGuiseppi,
AU  - C.
AU  - Gough,
AU  - D.
AU  - A.
AU  - Taylor,
AU  - R.
AU  - S.
AU  - Logan,
AU  - S.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1001/archpedi.156.8.752
DP  - Ovid Technologies
J2  - Arch Pediatr Adolesc Med
KW  - Adolescent Adolescent Behavior Aggression Chi-Square Distribution Child Child Behavior Curriculum Female Humans Male Randomized Controlled Trials as Topic Risk Factors *School Health Services/og [Organization &amp; Administration] Sex Factors *Violence/pc [
L1  - internal-pdf://0128919018/Mytton-2002-School-based violence prevention p.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Mytton, Julie A DiGuiseppi, Carolyn Gough, David A Taylor, Rod S Logan, Stuart Comment in: Arch Pediatr Adolesc Med. 2002 Aug;156(8):748-9; PMID: 12144362
PY  - 2002
SP  - 752-62
T2  - Archives of Pediatrics and Adolescent Medicine
TI  - School-based violence prevention programs: systematic review of secondary prevention trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=12144364 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:12144364&amp;id=doi:&amp;issn=1072-4710&amp;isbn=&amp;volume=156&amp;issue=8&amp;spage=752&amp;pages=752-62&amp;date=2002&amp;title=Archives+of+Pediatrics+%26+Adolescent+Medicine&amp;atitle=School-based+violence+prevention+programs%3A+systematic+review+of+secondary+prevention+trials.&amp;aulast=Mytton&amp;pid=%3Cauthor%3EMytton+JA%3C%2Fauthor%3E%3CAN%3E12144364%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://archpedi.jamanetwork.com/data/Journals/PEDS/5046/POA10369.pdf
UR  - https://jamanetwork.com/journals/jamapediatrics/articlepdf/203682/POA10369.pdf
VL  - 156
ER  -
TY  - JOUR
AB  - We located a comprehensive sample of studies (1980-1999) on the psychosocial and pharmacological treatment of child and adolescent depression through an extensive literature search. 

Articles that met the inclusionary criteria were subsequently analyzed. 

The outcome data from 38 studies were extracted and converted into effect sizes (ESs). Comparisons of main effects, demographic, and quality of study variables were conducted. 

The overall findings of this meta-analysis indicate that several different psychosocial interventions for child and adolescent depression produced moderate to large treatment gains that were clinically meaningful for many afflicted youth. 

However, in general, the vast majority of pharmacological interventions were not effective in treating depressed children and adolescents. 

Nonetheless, there is recent evidence that selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine are efficacious, and will likely play an increased role in the management of affective illness in youngsters. 

The clinical implications and limitations of these data are discussed and suggestions for future research are provided.
AD  - Michael,Kurt D. Appalachian State University, Boone, NC 28608, USA. michaelkd@appstate.edu
AN  - 11806021
AU  - Michael,
AU  - K.
AU  - D.
AU  - Crowley,
AU  - S.
AU  - L.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1016/S0272-7358(01)00089-7
DP  - Ovid Technologies
J2  - Clin Psychol Rev
KW  - Adolescent Antidepressive Agents/tu [Therapeutic Use] Child Clinical Trials as Topic Combined Modality Therapy Depressive Disorder/di [Diagnosis] Depressive Disorder/px [Psychology] *Depressive Disorder/th [Therapy] Humans Psychotherapy Serotonin Uptake
LA  - English
M3  - Meta-Analysis Review
N1  - Michael, Kurt D Crowley, Susan L
PY  - 2002
SP  - 247-69
T2  - Clinical Psychology Review
TI  - How effective are treatments for child and adolescent depression? A meta-analytic review
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=11806021 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:11806021&amp;id=doi:&amp;issn=0272-7358&amp;isbn=&amp;volume=22&amp;issue=2&amp;spage=247&amp;pages=247-69&amp;date=2002&amp;title=Clinical+Psychology+Review&amp;atitle=How+effective+are+treatments+for+child+and+adolescent+depression%3F+A+meta-analytic+review.&amp;aulast=Michael&amp;pid=%3Cauthor%3EMichael+KD%3C%2Fauthor%3E%3CAN%3E11806021%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0272735801000897/1-s2.0-S0272735801000897-main.pdf?_tid=bc723c76-23dc-11e5-8e79-00000aacb35e&amp;acdnat=1436186846_4047e2fa73da25408e15a6f0f519b84b
VL  - 22
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To determine by meta-analysis the effect size for stimulants on overt and covert aggression-related behaviors in children with attention-deficit/hyperactivity disorder (ADHD), separately from stimulant effects on the core symptoms of ADHD. 

**METHOD: **
A review of the literature from 1970 to 2001 revealed 28 studies meeting inclusion/exclusion criteria for meta-analysis. These studies yielded 28 independent effects of overt aggression and 7 independent effects of covert aggression.

**RESULTS: **
The overall weighted mean effect size was 0.84 for overt and 0.69 for covert aggression related behaviors in ADHD. Comorbid conduct disorder is associated with diminishing stimulant effect size for overt aggression. 

**CONCLUSION: **
Stimulant effects for aggression-related behaviors in ADHD have effect sizes similar to those for the core symptoms of ADHD.
AD  - (Connor, Glatt, Lopez, Jackson, Melloni Jr.) Division of Child and Adolescent Psychiatry, University of Massachusetts Medical School, Worcester 01655, USA. D.F. Connor, Division of Child and Adolescent Psychiatry, University of Massachusetts Medical School, Worcester 01655, USA.
AN  - 11886019
AU  - Connor,
AU  - D.
AU  - F.
AU  - Glatt,
AU  - S.
AU  - J.
AU  - Lopez,
AU  - I.
AU  - D.
AU  - Jackson,
AU  - D.
AU  - Melloni
AU  - Jr,
AU  - R.
AU  - H.
DA  - Mar
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1097/00004583-200203000-00004
DP  - Ovid Technologies
KW  - adolescent aggression article attention deficit disorder/dt [Drug Therapy] child clinical trial conduct disorder/di [Diagnosis] conduct disorder/et [Etiology] female human male meta analysis psychological aspect central stimulant agent/dt [Drug Therapy]
LA  - English
PY  - 2002
SP  - 253-261
T2  - Journal of the American Academy of Child and Adolescent Psychiatry
TI  - Psychopharmacology and aggression. I: A meta-analysis of stimulant effects on overt/covert aggression-related behaviors in ADHD
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed5&amp;AN=11886019 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:11886019&amp;id=doi:&amp;issn=0890-8567&amp;isbn=&amp;volume=41&amp;issue=3&amp;spage=253&amp;pages=253-261&amp;date=2002&amp;title=Journal+of+the+American+Academy+of+Child+and+Adolescent+Psychiatry&amp;atitle=Psychopharmacology+and+aggression.+I%3A+A+meta-analysis+of+stimulant+effects+on+overt%2Fcovert+aggression-related+behaviors+in+ADHD&amp;aulast=Connor&amp;pid=%3Cauthor%3EConnor+D.F.%3C%2Fauthor%3E%3CAN%3E11886019%3C%2FAN%3E%3CDT%3EJournal%3A+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0890856709607826/1-s2.0-S0890856709607826-main.pdf?_tid=273dd90a-1674-11e5-a40f-00000aacb362&amp;acdnat=1434712563_c6e40a83b77eb176fd6ec0972fb13bf2
VL  - 41
ER  -
TY  - JOUR
AB  - **Background:**
Enuresis (bed-wetting) is a socially disruptive and stressful condition which affects from 15% to 20% of five year olds, and up to 2% of young adults.

**Objectives:** 
To assess the effects of desmopressin on nocturnal enuresis in children, and to compare desmopressin with other interventions.

**Search methods:** 
We searched the Cochrane Incontinence Group Specialised Trials Register (searched 10 May 2006). The reference list of the original version of this review was also searched.Selection criteria: All randomised controlled trials of desmopressin for nocturnal enuresis in children were included in the review. Trials focused solely on daytime wetting were excluded.

**Data collection and analysis:**
 Two reviewers independently assessed the quality of the eligible trials and extracted data.

**Main results:**
Forty seven randomised controlled trials involving 3448 children (of whom 2210 received desmopressin) met the inclusion criteria. The quality of many of the trials was poor. Desmopressin was effective in reducing bed-wetting during treatment, compared with placebo (e.g. 20 &micro;g: 1.34 fewer wet nights per week; 95% confidence interval (CI) 1.11 to 1.57), and children were more likely to become dry (e.g. 118/146, 81% versus 140/142, 98% still wet; relative risk (RR) for failure to achieve 14 dry nights with 20 &micro;g was 0.84; 95% CI 0.79 to 0.91). However, there was no difference between the two patient groups after treatment was finished. There was no clear dose-related effect of desmopressin, but the evidence was limited. Data which compared oral and nasal administration were too few to be conclusive.In four small trials, there were no significant differences between desmopressin and alarms during treatment when these were used separately, but the chance of failure or relapse after treatment stopped was lower after an alarm in two small trials (40/62, 65% versus 26/57, 46%; RR 1.42, 95% CI 1.05 to 1.91).Although children had fewer wet nights during treatment when they used desmopressin combined with alarm treatment compared with alarms alone (WMD -0.83, 95% CI -1.11 to -0.55), there were no significant differences either in failure rates during treatment (RR 0.88; 95% CI 0.73 to 1.05) or for relapse after treatment stopped (105/213, 49% versus 118/214, 55%: RR 0.91, 95% CI 0.76 to 1.08).Comparison with some tricyclic drugs (e.g. amitriptyline) suggested that they might be as effective as desmopressin, although in two trials children were less likely to achieve 14 dry nights with imipramine than desmopressin (RR 0.44, 95% CI 0.27 to 0.73) but there was not enough information about subsequent relapse. There were more side effects with the tricyclics. Desmopressin may be better than diclofenac or indomethacin.There was not enough information to evaluate the relative effects of behavioural or complementary treatments against desmopressin.

**Authors&#039; conclusions:** 
Desmopressin rapidly reduced the number of wet nights per week experienced by children, but the limited evidence available suggested that this was not sustained after treatment stopped. Comparison with alternative treatments suggested that desmopressin and tricyclics had similar clinical effects during treatment, but that alarms may produce more sustained benefits. However, based on the available limited evidence, these conclusions are only tentative. Children should be advised not to drink more than 240 ml (8 ounces) of fluid during the evening before desmopressin treatment in order to avoid the possible risk of water intoxication.
AN  - CD002112
AU  - Glazener,
AU  - C.
AU  - M.
AU  - Evans,
AU  - J.
AU  - H.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd002112
KW  - Deamino Arginine Vasopressin [therapeutic use]
KW  - Enuresis [drug therapy]
KW  - Randomized Controlled Trials as Topic
KW  - Renal Agents [therapeutic use]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Incont
PY  - 2002
T2  - Cochrane Database of Systematic Reviews
TI  - Desmopressin for nocturnal enuresis in children
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002112/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD002112/asset/CD002112.pdf?v=1&amp;t=iw7j8zt4&amp;s=0671330e737e987ec67f1afff757fa2cacbfd6a6
ER  -
TY  - JOUR
AB  - **OBJECTIVE: **
To review the effectiveness of primary prevention strategies aimed at delaying sexual intercourse, improving use of birth control, and reducing incidence of unintended pregnancy in adolescents. 

**DATA SOURCES: **
12 electronic bibliographic databases, 10 key journals, citations of relevant articles, and contact with authors. 

**STUDY SELECTION: **
26 trials described in 22 published and unpublished reports that randomised adolescents to an intervention or a control group (alternate intervention or nothing). 

**DATA EXTRACTION: **
Two independent reviewers assessed methodological quality and abstracted data. 

**DATA SYNTHESIS: **
The interventions did not delay initiation of sexual intercourse in young women (pooled odds ratio 1.12; 95% confidence interval 0.96 to 1.30) or young men (0.99; 0.84 to 1.16); did not improve use of birth control by young women at every intercourse (0.95; 0.69 to 1.30) or at last intercourse (1.05; 0.50 to 2.19) or by young men at every intercourse (0.90; 0.70 to 1.16) or at last intercourse (1.25; 0.99 to 1.59); and did not reduce pregnancy rates in young women (1.04; 0.78 to 1.40). Four abstinence programmes and one school based sex education programme were associated with an increase in number of pregnancies among partners of young male participants (1.54; 1.03 to 2.29). There were significantly fewer pregnancies in young women who received a multifaceted programme (0.41; 0.20 to 0.83), though baseline differences in this study favoured the intervention. 

**CONCLUSIONS: **
Primary prevention strategies evaluated to date do not delay the initiation of sexual intercourse, improve use of birth control among young men and women, or reduce the number of pregnancies in young women.
AN  - 12065267
AU  - DiCenso,
AU  - A.
AU  - Guyatt,
AU  - G.
AU  - Willan,
AU  - A.
AU  - Griffith,
AU  - L.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - Tom verdi
L1  - internal-pdf://0235376785/DiCenso-2002-Interventions to reduce unintende.pdf
PY  - 2002
SP  - 1426
T2  - BMJ
TI  - Interventions to reduce unintended pregnancies among adolescents: systematic review of randomised controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=medc&amp;AN=12065267
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC115855/pdf/1426.pdf
VL  - 324
ER  -
TY  - JOUR
AB  - Rates of adolescent smoking appear to be on the increase, with a number of authors documenting increases in the 1990&#039;s. However, the issue of prevention rather than cessation has received greater attention in tobacco control programmes among youth. 

This review provides details of published school based and other tobacco cessation programmes for adolescents and compares their efficacy. 

Variations in outcome measures were noted with the programmes. 

Environmental risk factors such as economic deprivation, concurrent use of alcohol and illicit substances and a minority ethnic background have been associated with greater smoking rates among youth. 

It is suggested that tobacco cessation initiatives need to be considered in the context of improving adolescents&#039; lifestyle choices. Specific cessation programmes should also address issues such as appropriate follow-up and validation. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Stanton, Warren R.: w.stanton@mailbox.uq.edu.au Stanton, Warren R.: Centre for Health Promotion and Cancer Prevention Research, Faculty of Health Science, University of Queensland, Herston Rd, Herston, QLD, Australia, 4006, w.stanton@mailbox.uq.edu.au
AN  - 2004-11791-008
AU  - Stanton,
AU  - W.
AU  - R.
AU  - Smith,
AU  - K.
AU  - M.
DA  - Aug
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1006/jado.2002.0486
DP  - Ovid Technologies
KW  - adolescent smoking, smoking cessation programs *Adolescent Development *Lifestyle *Smoking Cessation *Tobacco Smoking Drug &amp; Alcohol Rehabilitation [3383] Human Male Female Childhood (birth-12 yrs) School Age (6-12 yrs) Adolescence (13-17 yrs) Adulthood
LA  - English
M3  - Literature Review
PY  - 2002
SP  - 427-438
T2  - Journal of Adolescence
TI  - A critique of evaluated adolescent smoking cessation programmes
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2004-11791-008 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1006%2Fjado.2002.0486&amp;issn=0140-1971&amp;isbn=&amp;volume=25&amp;issue=4&amp;spage=427&amp;pages=427-438&amp;date=2002&amp;title=Journal+of+Adolescence&amp;atitle=A+critique+of+evaluated+adolescent+smoking+cessation+programmes.&amp;aulast=Stanton&amp;pid=%3Cauthor%3EStanton%2C+Warren+R%3C%2Fauthor%3E%3CAN%3E2004-11791-008%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://ac.els-cdn.com/S0140197102904860/1-s2.0-S0140197102904860-main.pdf?_tid=6a790a06-165a-11e5-b0ef-00000aab0f27&amp;acdnat=1434701509_62b30af5bf2c88efc619f4ef88f1adaf
VL  - 25
ER  -
TY  - JOUR
AB  - This article reviews the empirical literature on psychosocial, psychopharmacological, and adjunctive treatments for children between the ages of 6 and 12 with internalizing disorders. 

The aim of this review was to identify interventions that have potential to prevent substance use disorders in adolescence by treating internalizing disorders in childhood. 

Results suggest that a variety of behavioral, cognitive-behavioral, and pharmacological interventions are effective in reducing symptoms of childhood depression, phobias, and anxiety disorders. None of the studies reviewed included substance abuse outcomes. 

Thus, little can be said about the relationship between early treatment and the prevention of later substance use. 

The importance of evaluating the generalizability of research-supported interventions to community settings is highlighted and recommendations for future research are offered.
AD  - Compton,Scott N. Department of Psychiatry and Behavioral Sciences, Durham, North Carolina 27705, USA. scompton@acpub.duke.edu
AN  - 12472300
AU  - Compton,
AU  - S.
AU  - N.
AU  - Burns,
AU  - B.
AU  - J.
AU  - Helen,
AU  - L.
AU  - E.
AU  - Robertson,
AU  - E.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1037/0022-006X.70.6.1240
DP  - Ovid Technologies
J2  - J Consult Clin Psychol
KW  - Adolescent Child Child Behavior Disorders/di [Diagnosis] Child Behavior Disorders/px [Psychology] *Child Behavior Disorders/th [Therapy] Combined Modality Therapy Female Humans *Internal-External Control Male Personality Development Risk Factors *Substa
LA  - English
M3  - Research Support, U.S. Gov&#039;t, P.H.S. Review
N1  - Compton, Scott N Burns, Barbara J Helen, L Egger Robertson, Elizabeth Comment in: Evid Based Ment Health. 2003 Aug;6(3):80-1; PMID: 12893791 263-MJ-91952 (United States PHS HHS)
PY  - 2002
SP  - 1240-66
T2  - Journal of Consulting and Clinical Psychology
TI  - Review of the evidence base for treatment of childhood psychopathology: internalizing disorders
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=12472300 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:12472300&amp;id=doi:&amp;issn=0022-006X&amp;isbn=&amp;volume=70&amp;issue=6&amp;spage=1240&amp;pages=1240-66&amp;date=2002&amp;title=Journal+of+Consulting+%26+Clinical+Psychology&amp;atitle=Review+of+the+evidence+base+for+treatment+of+childhood+psychopathology%3A+internalizing+disorders.&amp;aulast=Compton&amp;pid=%3Cauthor%3ECompton+SN%3C%2Fauthor%3E%3CAN%3E12472300%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://psycnet.apa.org/journals/ccp/70/6/1240.pdf
VL  - 70
ER  -
TY  - JOUR
AB  - **AIMS: **
To determine whether family and parenting interventions benefit children and adolescents with conduct disorder and delinquency. 

**METHODS: **
Meta-analysis of eight randomised controlled trials involving 749 children and adolescents (aged 10-17 years) with conduct disorder and/or delinquency. Criminality, academic performance, future employment, problem behaviour, family functioning, parental mental health, and peer relations were evaluated. 

**RESULTS: **
Family and parenting interventions significantly reduced the time spent by juvenile delinquents in institutions (weighted mean difference 51.34 days). There was also a significant reduction in the risk of a juvenile delinquent being rearrested (relative risk 0.66) and in their rate of subsequent arrests at 1-3 years (standardised mean difference -0.56). 

**CONCLUSIONS: **
The evidence suggests that family and parenting interventions for juvenile delinquents and their families have beneficial effects on reducing time spent in institutions and their criminal activity. In addition to the obvious benefit to the participant and their family, this may result in a cost saving for society.
AD  - Woolfenden,S R. Department of Paediatrics, Caroline Chisholm Centre, Locked Bag 7103, Liverpool BC NSW 1871. susanw@chw.edu.au
AN  - 11919097
AU  - Woolfenden,
AU  - S.
AU  - R.
AU  - Williams,
AU  - K.
AU  - Peat,
AU  - J.
AU  - K.
DA  - Apr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/adc.86.4.251
DP  - Ovid Technologies
J2  - Arch Dis Child
KW  - Adolescent Child Conduct Disorder/px [Psychology] *Conduct Disorder/th [Therapy] Crime Educational Status Employment Family Relations *Family Therapy/mt [Methods] Female Humans *Juvenile Delinquency/pc [Prevention &amp; Control] Juvenile Delinquency/px [Psy
L1  - internal-pdf://0033123921/Woolfenden-2002-Family and parenting intervent.pdf
LA  - English
M3  - Meta-Analysis Review
N1  - Woolfenden, S R Williams, K Peat, J K Comment in: J Pediatr. 2002 Nov;141(5):738; PMID: 12448428 Comment in: Evid Based Ment Health. 2002 Nov;5(4):123; PMID: 12440465
PY  - 2002
SP  - 251-6
T2  - Archives of Disease in Childhood
TI  - Family and parenting interventions for conduct disorder and delinquency: a meta-analysis of randomised controlled trials
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=11919097
UR  - http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:11919097&amp;id=doi:&amp;issn=0003-9888&amp;isbn=&amp;volume=86&amp;issue=4&amp;spage=251&amp;pages=251-6&amp;date=2002&amp;title=Archives+of+Disease+in+Childhood&amp;atitle=Family+and+parenting+interventions+for+conduct+disorder+and+delinquency%3A+a+meta-analysis+of+randomised+controlled+trials.&amp;aulast=Woolfenden&amp;pid=%3Cauthor%3EWoolfenden+SR%3C%2Fauthor%3E%3CAN%3E11919097%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1719168/pdf/v086p00251.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1719168/pdf/v086p00251.pdf
VL  - 86
ER  -
TY  - JOUR
AB  - **Background:** 
Eating disorders represent an extremely difficult, time-consuming and costly condition to treat. Being young, female, and dieting are some of the few identified risk factors that have been reliably linked to the development of eating disorders. There is currently limited evidence in the published literature to suggest that any particular type of program is effective in preventing eating disorders and there has been concern that some interventions have the potential to cause harm.

**Objectives:** 
To determine if eating disorder prevention programs for children and adolescents are effective in: (1) promoting healthy eating attitudes and behaviours; (2) promoting protective psychological factors; (3) promoting satisfactory physical health; (4) having a long-term, sustainable, and positive impact on mental and physical health; and, (5) ensuring safety in relation to possible harmful consequences on mental or physical health.

**Search methods:** 
Relevant trials are identified through searching the Cochrane Controlled Trial Register (CCTR) and relevant biomedical and social science databases, as well as reference lists from articles identified through the search strategy and contact with experts in the field.

**Selection criteria:** 
Randomised controlled trials (RCTs) with a major focus on eating disorder prevention programs for children and adolescents, where there is no known DSM-IV diagnosis of an eating disorder, are eligible for inclusion in the review. Trials must include a control group and at least one objective outcome measure (e.g., BMI) or a standardised psychological measure used with the intervention and control group, pre- and post-intervention.

**Data collection and analysis:** 
A total of 1016 titles have been identified through the search to date. Twenty-two studies were located that reported use of a randomised controlled trial methodology and were critically appraised by two independent reviewers. Twelve studies met the selection criteria outlined above.

**Main results:** 
Combined data from two eating disorder prevention programs based on a media literacy and advocacy approach indicate a reduction in the internalisation or acceptance of societal ideals relating to appearance at a 3- to 6-month follow-up (Kusel 1999; Neumark* 2000) [SMD -0.28, -0.51 to -0.05, 95% CI]. There is insufficient evidence to support the effect of five programs designed to address eating attitudes and behaviours and other adolescent issues in the general community or those classified as being at high risk for eating disorder (Buddeberg* 1998; Dalle Grave 2001; Killen 1993; Santonastaso 1999; Zanetti 1999) and insufficient evidence to support the effect of two programs designed to improve self-esteem (O&#039;Dea 2000; Wade 2003). Data from two didactic eating disorder awareness programs could not be pooled for analysis. There is not sufficient evidence to suggest that harm resulted from any of the prevention programs included in the review.

**Authors&#039; conclusions:** The one significant pooled effect in the current review does not allow for any firm conclusions to be made about the impact of prevention programs for eating disorders in children and adolescents, although none of the pooled comparisons indicated evidence of harm. The meta-analysis is in the process of being revised to account for the impact of cluster randomised trials.
AN  - CD002891
AU  - Pratt,
AU  - B.
AU  - M.
AU  - Woolfenden,
AU  - S.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd002891
KW  - Feeding and Eating Disorders [prevention &amp; control] [psychology]
KW  - Program Evaluation
KW  - Psychotherapy
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Depressn
PY  - 2002
T2  - Cochrane Database of Systematic Reviews
TI  - Interventions for preventing eating disorders in children and adolescents
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD002891/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD002891/asset/CD002891.pdf?v=1&amp;t=iw7ju7x7&amp;s=d6211e4778e3e43d8de3feb7fe8868fb3a06ba31
ER  -
TY  - JOUR
AB  - This meta-analysis examined 74 studies in which there had been an intervention that aimed to improve the behavioral, cognitive, and/or social functioning of people with attention deficit hyperactivity disorder (ADHD), or attention deficit disorder (ADD). Overall, there were larger effects of the various interventions on behavioral than on educational outcomes. These overall effects were larger for medical interventions than for educational, psychosocial, or parent training interventions, but there was little support for flow-over effects, from the reduction in behavior problems to enhanced educational outcomes. The effects on educational outcomes were greater for educational interventions than for other types of intervention. (PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Purdie, Nola: n.purdie@qut.edu.au; Hattie, John: j.hattie@auckland.ac.nz; Carroll, Annemaree: a.carroll@mailbox.uq.edu.au Purdie, Nola: Queensland U of Technology, Faculty of Education, Ctr for Cognitive Processes in Learning, Kelvin Grove, QLD, Australia Hattie, John: U Auckland, School of Education, Auckland, New Zealand Carroll, Annemaree: U Queensland, Schonell Special Education Research Ctr, Brisbane, QLD, Australia
AN  - 2002-18024-003
AU  - Purdie,
AU  - N.
AU  - Hattie,
AU  - J.
AU  - Carroll,
AU  - A.
DA  - Spr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.3102/00346543072001061
DP  - Ovid Technologies
KW  - attention deficit hyperactivity disorder, attention deficit disorder, behavioral interventions, educational outcomes, medical interventions, parent training interventions, behavior problems *Academic Achievement *Attention Deficit Disorder *Behavior Pro
LA  - English
M3  - Meta Analysis
PY  - 2002
SP  - 61-99
T2  - Review of Educational Research
TI  - A review of the research on interventions for attention deficit hyperactivity disorder: What works best?
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc4&amp;AN=2002-18024-003
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.3102%2F00346543072001061&amp;issn=0034-6543&amp;isbn=&amp;volume=72&amp;issue=1&amp;spage=61&amp;pages=61-99&amp;date=2002&amp;title=Review+of+Educational+Research&amp;atitle=A+review+of+the+research+on+interventions+for+attention+deficit+hyperactivity+disorder%3A+What+works+best%3F&amp;aulast=Purdie&amp;pid=%3Cauthor%3EPurdie%2C+Nola%3C%2Fauthor%3E%3CAN%3E2002-18024-003%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://rer.sagepub.com/content/72/1/61http://rer.sagepub.com/content/72/1/61.full.pdf
VL  - 72
ER  -
TY  - JOUR
AB  - Reviewed the scientific evidence on the effectiveness of early childhood educational programs. Drawing upon the theory that intelligence and related complex human behaviors are probably always determined by myriad complex interactions of genes and environments, this meta-analytic study is based on the assumption that such behaviors can be both highly heritable and highly malleable. 

Integrating results across 35 preschool experiments and quasi-experiments, the primary findings were: (a) preschool effects on standardized measures of intelligence and academic achievement were statistically significant, positive, and large; (b) cognitive effects of relatively intense educational interventions were significant and very large, even after 5-10 years, and 7-8 of every 10 preschool children did better than the average child in a control or comparison group; and (c) cumulative incidences of an array of personal and social problems were statistically, significantly, and substantially lower over a 10- to 25- year period for those who had attended preschool (e.g., school drop out, welfare dependence, unemployment, poverty, criminal behavior). 

The need for a very large, well-controlled, national experiment to either confirm or refute these provocative, review-generated findings is discussed. (PsycINFO Database Record (c) 2012 APA, all rights reserved).
AD  - Gorey, Kevin M.: U Windsor, School of Social Work, Windsor, ON, Canada
AN  - 2001-17154-001
AU  - Gorey,
AU  - K.
AU  - M.
DA  - Spr
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1521/scpq.16.1.9.19163
DP  - Ovid Technologies
KW  - early childhood education programs, short- &amp; long-term academic achievement &amp; intelligence &amp; personal &amp; social problems, preschool students *Academic Achievement *Cognitive Development *Educational Program Evaluation *Educational Programs *Psychosocial
LA  - English
M3  - Meta Analysis
PY  - 2001
SP  - 9-30
T2  - School Psychology Quarterly
TI  - Early childhood education: A meta-analytic affirmation of the short- and long-term benefits of educational opportunity
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc3&amp;AN=2001-17154-001
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1521%2Fscpq.16.1.9.19163&amp;issn=1045-3830&amp;isbn=&amp;volume=16&amp;issue=1&amp;spage=9&amp;pages=9-30&amp;date=2001&amp;title=School+Psychology+Quarterly&amp;atitle=Early+childhood+education%3A+A+meta-analytic+affirmation+of+the+short-+and+long-term+benefits+of+educational+opportunity.&amp;aulast=Gorey&amp;pid=%3Cauthor%3EGorey%2C+Kevin+M%3C%2Fauthor%3E%3CAN%3E2001-17154-001%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://psycnet.apa.org/journals/spq/16/1/9.pdf
VL  - 16
ER  -
TY  - JOUR
AB  - **BACKGROUND: **
Numerous small clinical trials have been carried out to study the behaviourally defined efficacy and safety of short-acting methylphenidate compared with placebo for attention-deficit disorder (ADD) in individuals aged 18 years and less. However, no meta-analyses that carefully examined these questions have been done. We reviewed the behavioural evidence from all the randomized controlled trials that compared methylphenidate and placebo, and completed a meta-analysis. 

**METHODS: **
We searched several electronic sources for articles published between 1981 and 1999: MEDLINE, EMBASE, PsychINFO, ERIC, CINAHL, HEALTHSTAR, Biological Abstracts, Current Contents and Dissertation Abstracts. The Cochrane Library Trials Registry and Current Controlled Trials were also consulted. A study was considered eligible for inclusion if it entailed the following: a placebo-controlled randomized trial that involved short-acting methylphenidate and participants aged 18 years or less at the start of the trial who had received any primary diagnosis of ADD that was made in a systematic and reproducible way. 

**RESULTS: **
We included 62 randomized trials that involved a total of 2897 participants with a primary diagnosis of ADD (e.g., with or without hyperactivity). The median age of trial participants was 8.7 years, and the median &quot;percent male&quot; composition of trials was 88.1%. Most studies used a crossover design. Using the scores from 2 separate indices, this collection of trials exhibited low quality. Interventions lasted, on average, 3 weeks, with no trial lasting longer than 28 weeks. Each primary outcome (hyperactivity index) demonstrated a significant effect of methylphenidate (effect size reported by teacher 0.78, 95% confidence interval [CI] 0.64-0.91; effect size reported by parent 0.54, 95% CI 0.40-0.67). However, these apparent beneficial effects are tempered by a strong indication of publication bias and the lack of robustness of the findings, especially those involving core ADD features. Methylphenidate also has an adverse event profile that requires consideration. For example, clinicians only need to treat 4 children to identify an episode of decreased appetite. 

**INTERPRETATION: **
Short-acting methylphenidate has a statistically significant clinical effect in the short-term treatment of individuals with a diagnosis of ADD aged 18 years and less. However, the extension of this placebo-controlled effect beyond 4 weeks of treatment has not been demonstrated. Exact knowledge of the extent and definition of the short-term behavioural usefulness of methylphenidate is questioned.
AD  - Schachter,H M. Thomas C. Chalmers Centre for Systematic Reviews, Children&#039;s Hospital of Eastern Ontario Research Institute, Ottawa. hschacht@uottawa.ca
AN  - 11762571
AU  - Schachter,
AU  - H.
AU  - M.
AU  - Pham,
AU  - B.
AU  - King,
AU  - J.
AU  - Langford,
AU  - S.
AU  - Moher,
AU  - D.
DA  - Nov 27
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pubmed/11762571
DP  - Ovid Technologies
J2  - Cmaj
KW  - Adolescent Adult Age Factors Anorexia/ci [Chemically Induced] Attention Deficit Disorder with Hyperactivity/cl [Classification] *Attention Deficit Disorder with Hyperactivity/dt [Drug Therapy] Attention Deficit Disorder with Hyperactivity/px [Psychology
L1  - internal-pdf://4198516322/Schachter-2001-How efficacious and safe is sho.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Schachter, H M Pham, B King, J Langford, S Moher, D Comment in: CMAJ. 2001 Nov 27;165(11):1505-6; PMID: 11762576 Comment in: CMAJ. 2002 May 14;166(10):1251-2; PMID: 12041836 Comment in: Evid Based Ment Health. 2002 May;5(2):50; PMID: 12026899
PY  - 2001
SP  - 1475-88
T2  - CMAJ Canadian Medical Association Journal
TI  - How efficacious and safe is short-acting methylphenidate for the treatment of attention-deficit disorder in children and adolescents? A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=11762571 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:11762571&amp;id=doi:&amp;issn=0820-3946&amp;isbn=&amp;volume=165&amp;issue=11&amp;spage=1475&amp;pages=1475-88&amp;date=2001&amp;title=CMAJ+Canadian+Medical+Association+Journal&amp;atitle=How+efficacious+and+safe+is+short-acting+methylphenidate+for+the+treatment+of+attention-deficit+disorder+in+children+and+adolescents%3F+A+meta-analysis.&amp;aulast=Schachter&amp;pid=%3Cauthor%3ESchachter+HM%3C%2Fauthor%3E%3CAN%3E11762571%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC81663/pdf/20011127s00013p1475.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC81663/pdf/20011127s00013p1475.pdf
VL  - 165
ER  -
TY  - JOUR
AB  - A meta-analysis of play therapy outcomes with children aged 0-12 yrs was conducted to determine the overall effectiveness of play therapy and the variables related to effectiveness. Hierarchical linear modelling was used to analyze the data. The analysis showed an average treatment effect of 0.66 standard deviations. A strong relationship between treatment effectiveness and the inclusion of parents in the therapeutic process was reported. The duration of therapy also appeared to be related to treatment outcomes, with maximum effect sizes occurring after approximately 30 treatment sessions. Play therapy appeared to be as effective as non-play therapies in treating children experiencing emotional difficulties. Recommendations for future researchers focus on explaining therapeutic or participant characteristics that are related to treatment effectiveness. (PsycINFO Database Record (c) 2012 APA, all rights reserved).
AD  - Leblanc, Michael: SUNY Oswego, Counseling &amp; Psychological Services, Oswego, NY, US, 13126 Leblanc, Michael: State U New York, Coll at Oswego, Oswego, NY, US
AN  - 2001-11782-007
AU  - Leblanc,
AU  - M.
AU  - Ritchie,
AU  - M.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1080/09515070110059142
DP  - Ovid Technologies
KW  - play therapy outcomes, effectiveness *Play Therapy *Treatment Outcomes Psychotherapy &amp; Psychotherapeutic Counseling [3310] Human Childhood (birth-12 yrs) Neonatal (birth-1 mo) Infancy (2-23 mo) Preschool Age (2-5 yrs) School Age (6-12 yrs)
LA  - English
M3  - Meta Analysis
PY  - 2001
SP  - 149-163
T2  - Counselling Psychology Quarterly
TI  - A meta-analysis of play therapy outcomes
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc3&amp;AN=2001-11782-007
UR  - http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1080%2F09515070110059142&amp;issn=0951-5070&amp;isbn=&amp;volume=14&amp;issue=2&amp;spage=149&amp;pages=149-163&amp;date=2001&amp;title=Counselling+Psychology+Quarterly&amp;atitle=A+meta-analysis+of+play+therapy+outcomes.&amp;aulast=Leblanc&amp;pid=%3Cauthor%3ELeblanc%2C+Michael%3C%2Fauthor%3E%3CAN%3E2001-11782-007%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1080/09515070110059142
VL  - 14
ER  -
TY  - JOUR
AB  - **Background:** 
Conduct disorder and delinquency are significant problems for children and adolescents and their families, with the potential to consume much of the resources of the health, social care and juvenile justice systems. A number of family and parenting interventions have been recommended and are used for these conditions. The aim of this review was to determine if these interventions are effective in the management of conduct disorder and delinquency in children and adolescents, aged 10-17.

**Objectives:** 
To determine if family and parenting interventions improve the child/adolescent&#039;s behaviour; parenting and parental mental health; family functioning and relations; and have an effect on the long term psychosocial outcomes for the child/adolescent.

**Search methods:** 
Randomised controlled trials were identified in September 1999 through searching the Cochrane Controlled Trial Register (CCTR), databases (MEDLINE, EMBASE, PsycINFO, CINAHL, Sociofile, ERIC, Healthstar), reference lists of articles and contact with authors.

**Selection criteria:** 
Randomised controlled trials with a major focus on parenting and/or family functioning were eligible for inclusion in the review. Trials needed to include at least one objective outcome measure (e.g. arrest rates) or have used a measure that had been published in peer review publications and validated for the relevant purpose. Studies were required to have a control group, which could be a no intervention group, a wait list group or a usual intervention group (e.g. probation).Trials in children and adolescents aged 10 to 17 years with conduct disorder and/or delinquency and their families were considered. Conduct disorder was defined by a standardised psychological assessment (for example, using a child behaviour checklist), or a psychiatric diagnosis. Delinquency was defined by a referral from a juvenile justice or another legal system for a child/adolescent who has committed a serious crime e.g assault and/or offended on at least two occasions.

**Data collection and analysis:** 
Two reviewers independently reviewed all eligible studies for inclusion, assessed study quality (allocation concealment, blinding, follow up, clinically important outcomes) and extracted data. Heterogeneity was assessed using the Chi squared test of heterogeneity along with visual inspection of the data. A significance level less than 0.1 was interpreted as evidence of statistically significant heterogeneity. For data where heterogeneity was found the reviewers looked for an explanation. If studies with heterogeneous results were thought to be comparable the statistical synthesis of the results was done using a random effects model. This model takes into account within-study sampling error and between-studies variation in the assessment of uncertainty and will give wider confidence intervals to the effect size and hence a more conservative result.Sensitivity analysis was performed to explore the effects of the varying quality of the studies included on the results.

**Main results:** 
Of the nine hundred and seventy titles initially identified through the search strategy, eight trials met the inclusion criteria. A total of 749 children and their families were randomised to receive a family and parenting intervention or to be in a control group. In seven of these studies the participants were juvenile delinquents and their families and in only one the participants were children/adolescents with conduct disorder who had not yet had contact with the juvenile justice system.At follow up, family and parenting interventions significantly reduced the time spent by juvenile delinquents in institutions (WMD 51.34 days, 95%CI 72.52 to 30.16). There was also a significant reduction in the risk of a juvenile delinquent being re arrested (RR 0.66, 95%CI 0.44 to 0.98) and in their rate of subsequent arrests at 1-3 years (SMD -0.56, 95% CI -1.100 to - 0.03). For both of these outcomes there was substantial heterogeneity in the results suggesting a need for caution in interpretation. At present there is insufficient evidence that f m ly and parenting interventions reduce the risk of being incarcerated (RR=0.50, 95% CI 0.20 to 1.21). No significant difference was found for psychosocial outcomes such as family functioning, and child/adolescent behaviour.

**Authors&#039; conclusions:** 
The evidence suggests that family and parenting interventions for juvenile delinquents and their families have beneficial effects on reducing time spent in institutions. This has an obvious benefit to the participant and their family and may result in a cost saving for society. These interventions may also reduce rates of subsequent arrest but at present these results need to be interpreted with caution due to the heterogeneity of the results.
AN  - CD003015
AU  - Woolfenden,
AU  - S.
AU  - Williams,
AU  - K.
AU  - J.
AU  - Peat,
AU  - J.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1002/14651858.cd003015
KW  - Family Therapy
KW  - Parenting
KW  - Adolescent Behavior
KW  - Child Behavior Disorders [therapy]
KW  - Juvenile Delinquency [prevention &amp; control]
KW  - Randomized Controlled Trials as Topic
KW  - Social Behavior Disorders [therapy]
KW  - Adolescent[checkword]
KW  - Child[checkword]
KW  - Humans[checkword]
KW  - Behav
PY  - 2001
T2  - Cochrane Database of Systematic Reviews
TI  - Family and parenting interventions in children and adolescents with conduct disorder and delinquency aged 10-17
UR  - http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003015/abstracthttp://onlinelibrary.wiley.com/store/10.1002/14651858.CD003015/asset/CD003015.pdf?v=1&amp;t=iw7jfm9q&amp;s=b405622861aa86456e08e70aa8ba190701cef659
ER  -
TY  - JOUR
AB  - **OBJECTIVES: **
To assess the efficacy of treatments for settling problems and night waking in young children. 

**DESIGN: **
A systematic review of randomised controlled trials of interventions for settling problems and night waking in young children. 

**SETTING: **
Electronic bibliographic databases and references on identified papers, hand searches, and personal contact with specialists. 

**SUBJECTS: **
Children aged 5 years or less who had established settling problems or night waking. 

**INTERVENTIONS: **
Interventions had to be described and a placebo, waiting list, or another intervention needed to have been used as a comparison. Interventions comprised drug trials or non-drug trials. 

**MAIN OUTCOME MEASURES: **
Number of wakes at night, time to settle, or number of nights in which these problems occurred. 

**RESULTS: **
Drugs seemed to be effective in treating night waking in the short term, but long term efficacy was questionable. In contrast, specific behavioural interventions showed both short term efficacy and possible longer term effects for dealing with settling problems and night waking. 

**CONCLUSIONS: **
Given the prevalence and persistence of childhood sleep problems and the effects they can have on children and families, treatments that offer long lasting benefits are appealing and these are likely to be behavioural interventions.
AD  - Ramchandani,P. University of Oxford Section of Child and Adolescent Psychiatry, Park Hospital for Children, Headington, Oxford OX3 7LQ. paulgulab@aol.com
AN  - 10642226
AU  - Ramchandani,
AU  - P.
AU  - Wiggs,
AU  - L.
AU  - Webb,
AU  - V.
AU  - Stores,
AU  - G.
DA  - Jan 22
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1136/bmj.320.7229.209
DP  - Ovid Technologies
J2  - Bmj
KW  - Behavior Therapy/mt [Methods] Child, Preschool Follow-Up Studies Humans Infant Infant, Newborn Randomized Controlled Trials as Topic/st [Standards] Sleep Disorders/dt [Drug Therapy] *Sleep Disorders/th [Therapy] *Wakefulness/ph [Physiology]
L1  - internal-pdf://2107137709/Ramchandani-2000-A systematic review of treatm.pdf
LA  - English
M3  - Meta-Analysis Research Support, Non-U.S. Gov&#039;t
N1  - Ramchandani, P Wiggs, L Webb, V Stores, G Comment in: BMJ. 2000 Jun 17;320(7250):1668; PMID: 10905836 Comment in: BMJ. 2000 Jun 17;320(7250):1667-8; author reply 1668; PMID: 10905835 Comment in: BMJ. 2000 Jun 17;320(7250):1667; author reply 1668; PMID: 10905834 Comment in: BMJ. 2000 Jun 17;320(7250):1667; author reply 1668; PMID: 10905833 Comment in: ACP J Club. 2000 Sep-Oct;133(2):61
PY  - 2000
SP  - 209-13
T2  - BMJ
TI  - A systematic review of treatments for settling problems and night waking in young children
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=med4&amp;AN=10642226 http://openurl.bibsys.no/openurl?sid=OVID:medline&amp;id=pmid:10642226&amp;id=doi:&amp;issn=0959-8138&amp;isbn=&amp;volume=320&amp;issue=7229&amp;spage=209&amp;pages=209-13&amp;date=2000&amp;title=BMJ&amp;atitle=A+systematic+review+of+treatments+for+settling+problems+and+night+waking+in+young+children.&amp;aulast=Ramchandani&amp;pid=%3Cauthor%3ERamchandani+P%3C%2Fauthor%3E%3CAN%3E10642226%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC27265/pdf/209.pdf
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC27265/pdf/209.pdf
VL  - 320
ER  -
TY  - JOUR
AB  - Studies examining interventions for adolescents diagnosed with attention-deficit/hyperactivity disorder (ADHD) were reviewed to evaluate their efficacy. 

These efficacy findings were supplemented with a preliminary system for judging safety and practicality. 

Results suggest that the stimulant drug methylphenidate (MPH) is safe and well-established empirically, but has some problems with inconvenience and noncompliance. 

Preliminary research supports the efficacy, safety, and practicality of some psychotherapeutic interventions, including behavioral classroom interventions, note-taking training, and family therapy. 

Treatment with tricyclic antidepressants was judged to have minimal empirical support and debatable safety. 

Very little is known about long-term effectiveness of treatments, long-term compliance, or multimodal treatments for adolescents such as stimulants plus behavior therapy.
AD  - (Smith, Waschbusch, Willoughby, Evans) Department of Psychology, University of South Carolina 29206, USA. B.H. Smith, Department of Psychology, University of South Carolina 29206, USA.
AN  - 11225739
AU  - Smith,
AU  - B.
AU  - H.
AU  - Waschbusch,
AU  - D.
AU  - A.
AU  - Willoughby,
AU  - M.
AU  - T.
AU  - Evans,
AU  - S.
DA  - Dec
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - https://www.ncbi.nlm.nih.gov/pubmed/11225739
DP  - Ovid Technologies
KW  - adolescent attention deficit disorder/di [Diagnosis] attention deficit disorder/th [Therapy] human psychotherapy review treatment outcome central stimulant agent/ae [Adverse Drug Reaction] central stimulant agent/dt [Drug Therapy] tricyclic antidepressa
LA  - English
M3  - Review
PY  - 2000
SP  - 243-267
T2  - Clinical child and family psychology review
TI  - The efficacy, safety, and practicality of treatments for adolescents with attention-deficit/hyperactivity disorder (ADHD)
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=emed5&amp;AN=11225739 http://openurl.bibsys.no/openurl?sid=OVID:embase&amp;id=pmid:11225739&amp;id=doi:&amp;issn=1096-4037&amp;isbn=&amp;volume=3&amp;issue=4&amp;spage=243&amp;pages=243-267&amp;date=2000&amp;title=Clinical+child+and+family+psychology+review&amp;atitle=The+efficacy%2C+safety%2C+and+practicality+of+treatments+for+adolescents+with+attention-deficit%2Fhyperactivity+disorder+%28ADHD%29&amp;aulast=Smith&amp;pid=%3Cauthor%3ESmith+B.H.%3C%2Fauthor%3E%3CAN%3E11225739%3C%2FAN%3E%3CDT%3EJournal%3A+Review%3C%2FDT%3E
VL  - 3
ER  -
TY  - JOUR
AB  - Conducted a meta-analytic evaluation of the effectiveness of school-based child abuse prevention programs. 

Literature searches identified 27 studies meeting inclusion criteria for use in this meta-analysis. 

The average effect size for all programs studied was 1.07, indicating that children who participated in prevention programs perform 1.07 SD higher than control group children on the outcome measures used in the studies. 

Analysis of moderator variables revealed significant effects for age, number of sessions, participant involvement, type of outcome measure, and use of behavioral skills training. 

Most important, programs presented over 4 or more sessions that allowed children to become physically involved produced the highest effect sizes. 

Although most often used only with younger children, findings suggest that active, long-term programs may be more effective for children of all ages. 

(PsycINFO Database Record (c) 2012 APA, all rights reserved) (journal abstract).
AD  - Katherine Davis, M. Katherine: Ohio U, Dept of Psychology, Athens, OH, US
AN  - 2000-07691-010
AU  - Davis,
AU  - M.
AU  - Gidycz,
AU  - C.
AU  - A.
DA  - Jun
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - /10.1207/S15374424jccp2902_11
DP  - Ovid Technologies
KW  - methodological issues &amp; program &amp; participant related characteristics as variables influencing effect sizes in meta-analysis of school-based child abuse prevention programs for 3-13 yr olds *Child Abuse *Educational Programs *Prevention *Schools Client
LA  - English
M3  - Meta Analysis
PY  - 2000
SP  - 257-265
T2  - Journal of Clinical Child Psychology
TI  - Child sexual abuse prevention programs: A meta-analysis
UR  - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;CSC=Y&amp;NEWS=N&amp;PAGE=fulltext&amp;D=psyc3&amp;AN=2000-07691-010 http://openurl.bibsys.no/openurl?sid=OVID:psycdb&amp;id=pmid:&amp;id=doi:10.1207%2FS15374424jccp2902_11&amp;issn=0047-228X&amp;isbn=&amp;volume=29&amp;issue=2&amp;spage=257&amp;pages=257-265&amp;date=2000&amp;title=Journal+of+Clinical+Child+Psychology&amp;atitle=Child+sexual+abuse+prevention+programs%3A+A+meta-analysis.&amp;aulast=Davis&amp;pid=%3Cauthor%3EDavis%2C+M.+Katherine%3C%2Fauthor%3E%3CAN%3E2000-07691-010%3C%2FAN%3E%3CDT%3EJournal+Article%3C%2FDT%3Ehttp://www.tandfonline.com/doi/pdf/10.1207/S15374424jccp2902_11
VL  - 29
ER  -
TY  - JOUR
AB  - The present meta-analysis reviewed 30 studies comparing child-based cognitive-behavioral therapy (CBT) for antisocial behavior with no-treatment, attention or wait-list control groups. 

The mean effect size d of CBT interventions was 0.48 (median 0.26) unweighted and 0.23 weighted at post-treatment. The mean effect size at follow-up was 0.66 (median = 0.32) unweighted and 0.51 weighted. 

Hence, child-based CBT interventions have a small to moderate effect in decreasing antisocial behavior. Study quality was negatively correlated with post-treatment effect size. 

A trend was found for child age to correlate positively with post-treatment effect size, suggesting that current child-based CBT interventions for antisocial behavior are more effective for adolescents and older elementary-school aged children than fur younger elementary-school aged children. 

Treatment components, number of treatment sessions, session length, sessions per week, use of a clinical vs. nonclinical sample, type of control group, source of outcome ratings and publication year were unrelated to treatment efficacy. 

Future research directions, including the integration of individual training into group therapy and the examination of antisocial behavior subtypes (i.e., reactive vs. proactive), are discussed.
AD  - Med Coll Penn &amp; Hahnemann Univ, Philadelphia, PA USA. Wordsworth Acad, Ft Washington, PA 19034 USA. Bennett, DS (reprint author), Eastern Penn Psychiat Inst, Div Child &amp; Adolescent Psychiat, 3200 Henry Ave, Philadelphia, PA 19129 USA.
AN  - WOS:000086528300001
AU  - Bennett,
AU  - D.
AU  - S.
AU  - Gibbons,
AU  - T.
AU  - A.
DB  - Inkluderte IN SUM gigasok_cochrane_campbell.enl
DO  - 10.1300/J019v22n01_01
J2  - Child Fam. Behav. Ther.
KW  - antisocial behavior conduct problems cognitive-behavioral therapy treatment children adolescents CONDUCT-DISORDERED CHILDREN AGGRESSIVE-CHILDREN HIGH-RISK ADOLESCENTS METAANALYSIS PROGRAM BOYS PSYCHOTHERAPY COMPETENCE STUDENTS Psychology, Clinical Famil
LA  - English
M3  - Article; Proceedings Paper
N1  - ISI Document Delivery No.: 305FG Times Cited: 44 Cited Reference Count: 64 Bennett, DS Gibbons, TA Annual Meeting of the Association-for-Advancement-of-Behavior-Therapy NOV 05-08, 1998 WASHINGTON, D.C. Assoc Advancement Behav Therapy 44 HAWORTH PRESS INC BINGHAMTON CHILD FAM BEHAV THER
PY  - 2000
SP  - 1-15
T2  - Child and Family Behavior Therapy
TI  - Efficacy of child cognitive-behavioral interventions for antisocial behavior: A meta-analysis
UR  - &lt;Go to ISI&gt;://WOS:000086528300001http://www.tandfonline.com/doi/pdf/10.1300/J019v22n01_01
VL  - 22
ER  -